# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Cation_efflux PF01545.21 OWF34059.1 - 1.9e-44 151.8 7.1 3.6e-44 150.9 7.1 1.5 1 0 0 1 1 1 1 Cation efflux family DUF1282 PF06930.12 OWF34059.1 - 0.023 14.5 6.2 0.7 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Colicin_V PF02674.16 OWF34059.1 - 1.5 8.8 7.9 3.7 7.5 3.6 2.7 2 1 1 3 3 3 0 Colicin V production protein BTB PF00651.31 OWF34060.1 - 3.8e-41 139.8 4.3 4.8e-21 75.1 0.1 4.2 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.22 OWF34060.1 - 1.6e-39 135.1 0.0 3e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF34060.1 - 3.7e-10 40.1 0.0 1.1e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase BACK PF07707.15 OWF34060.1 - 0.0022 18.0 0.1 0.45 10.6 0.0 3.2 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 OWF34061.1 - 5.7e-28 97.4 0.9 5e-17 62.1 0.1 3.2 3 1 0 3 3 3 2 BTB/POZ domain Ras PF00071.22 OWF34061.1 - 9.1e-13 48.1 0.0 8.8e-12 44.9 0.0 2.3 1 1 1 2 2 2 1 Ras family Ntox10 PF15520.6 OWF34061.1 - 0.0065 16.4 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Novel toxin 10 Roc PF08477.13 OWF34061.1 - 0.11 12.7 0.0 0.48 10.7 0.0 2.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase BTB PF00651.31 OWF34062.1 - 6.7e-39 132.6 6.0 8.1e-23 80.8 0.1 3.8 3 1 0 3 3 3 2 BTB/POZ domain BACK PF07707.15 OWF34062.1 - 8.8e-05 22.6 0.5 0.087 12.9 0.1 3.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch Ras PF00071.22 OWF34062.1 - 0.005 16.4 0.0 0.015 14.9 0.0 1.9 1 0 0 1 1 1 1 Ras family DisA_N PF02457.16 OWF34062.1 - 0.035 13.7 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Ras PF00071.22 OWF34063.1 - 3.4e-28 98.3 0.0 4e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF34063.1 - 2.3e-11 44.0 0.0 2.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF34064.1 - 8.2e-53 178.3 0.0 1.6e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 Ras family BTB PF00651.31 OWF34064.1 - 2e-36 124.6 4.0 1.5e-19 70.3 0.0 3.6 4 0 0 4 4 4 3 BTB/POZ domain Roc PF08477.13 OWF34064.1 - 2.1e-21 76.4 0.0 5.5e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF34064.1 - 7.7e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2850 PF11012.8 OWF34064.1 - 0.0019 18.5 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2850) BACK PF07707.15 OWF34064.1 - 0.038 14.1 0.2 1.4 9.0 0.1 2.9 3 0 0 3 3 3 0 BTB And C-terminal Kelch NAD_binding_2 PF03446.15 OWF34065.1 - 3.3e-27 95.6 0.3 3.9e-27 95.4 0.3 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Homeodomain PF00046.29 OWF34066.1 - 2.8e-23 81.5 4.2 4.5e-23 80.9 4.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF34066.1 - 0.026 14.4 1.3 0.069 13.1 0.3 2.1 2 0 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 OWF34067.1 - 6.7e-22 77.1 4.8 6.7e-22 77.1 4.8 2.0 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 OWF34068.1 - 1.9e-22 78.8 8.9 3.1e-22 78.1 8.9 1.3 1 0 0 1 1 1 1 Homeodomain RAM PF15320.6 OWF34068.1 - 0.029 14.9 0.2 0.078 13.6 0.2 1.7 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Homeobox_KN PF05920.11 OWF34068.1 - 0.066 13.1 2.0 0.17 11.8 0.9 2.1 2 0 0 2 2 2 0 Homeobox KN domain DUF2209 PF09974.9 OWF34068.1 - 0.088 13.1 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Med15 PF09606.10 OWF34068.1 - 0.38 9.4 10.8 0.52 8.9 10.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Homeodomain PF00046.29 OWF34069.1 - 1.5e-22 79.2 11.6 1.7e-22 79.0 9.3 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF34069.1 - 0.0027 17.5 5.6 0.027 14.4 0.8 2.6 2 0 0 2 2 2 2 Homeobox KN domain DUF2209 PF09974.9 OWF34069.1 - 0.031 14.6 0.4 0.077 13.3 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Hamartin PF04388.12 OWF34069.1 - 0.07 11.8 7.7 0.088 11.5 7.7 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2076 PF09849.9 OWF34069.1 - 6.6 6.7 9.0 9.4 6.2 9.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Homeodomain PF00046.29 OWF34070.1 - 5.6e-22 77.4 9.0 9.1e-22 76.7 9.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF34070.1 - 0.034 14.1 0.4 0.088 12.7 0.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 OWF34070.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 OWF34071.1 - 3e-21 75.0 9.6 3.8e-21 74.7 8.1 1.9 2 0 0 2 2 2 1 Homeodomain DUF2209 PF09974.9 OWF34071.1 - 0.072 13.4 0.2 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 OWF34072.1 - 3.1e-20 71.8 6.9 4.9e-20 71.1 6.9 1.3 1 0 0 1 1 1 1 Homeodomain DUF4266 PF14086.6 OWF34072.1 - 2.1 9.4 9.1 1.8 9.5 5.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Homeodomain PF00046.29 OWF34073.1 - 3.3e-20 71.7 9.4 6.6e-20 70.7 9.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 OWF34074.1 - 2.1e-19 69.1 9.1 3.9e-19 68.2 9.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 OWF34075.1 - 9.7e-19 67.0 7.2 4e-18 65.0 7.9 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF34075.1 - 0.051 13.5 1.0 0.12 12.3 1.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Clat_adaptor_s PF01217.20 OWF34076.1 - 9.2e-34 116.4 0.8 1.3e-33 116.0 0.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SWIRM-assoc_2 PF16496.5 OWF34077.1 - 8.7e-180 598.0 22.1 8.7e-180 598.0 22.1 2.4 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 OWF34077.1 - 6.2e-31 106.6 0.1 1.5e-30 105.4 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 OWF34077.1 - 5.2e-29 100.1 14.9 1.6e-28 98.4 14.9 1.9 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM-assoc_3 PF16498.5 OWF34077.1 - 2.8e-28 98.0 3.0 2.8e-28 98.0 3.0 3.0 2 1 0 2 2 2 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 OWF34077.1 - 5.8e-12 45.6 0.1 1.3e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF34077.1 - 2e-07 31.1 0.0 6.4e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain BAR PF03114.18 OWF34078.1 - 9.1e-28 97.5 11.7 1.5e-27 96.8 11.7 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 OWF34078.1 - 5.7e-12 45.3 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF34078.1 - 2.7e-09 36.5 0.2 6.2e-09 35.3 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF34078.1 - 3.2e-09 36.3 0.0 6.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 OWF34078.1 - 0.1 12.3 7.2 0.23 11.1 7.2 1.6 1 0 0 1 1 1 0 BAR domain of APPL family FAM91_C PF14648.6 OWF34078.1 - 0.18 10.6 3.8 0.11 11.3 0.1 2.2 2 1 0 2 2 2 0 FAM91 C-terminus Synaptobrevin PF00957.21 OWF34078.1 - 0.69 9.8 4.3 0.19 11.5 0.8 1.9 2 0 0 2 2 2 0 Synaptobrevin DUF1664 PF07889.12 OWF34078.1 - 2.6 8.1 9.5 0.54 10.3 1.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Rpn3_C PF08375.11 OWF34079.1 - 3.2e-28 97.9 1.4 7.1e-28 96.8 1.4 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OWF34079.1 - 2e-22 79.7 2.2 2.7e-22 79.3 0.1 2.3 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OWF34079.1 - 0.00025 21.0 0.1 0.00057 19.9 0.1 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 OWF34079.1 - 0.017 15.2 1.7 0.017 15.2 1.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OWF34079.1 - 0.047 13.6 0.5 0.14 12.0 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF34079.1 - 0.38 11.1 8.4 2.1 8.7 0.7 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat NCD2 PF04905.13 OWF34080.1 - 4.7e-51 172.0 0.6 8.6e-51 171.1 0.6 1.5 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 OWF34080.1 - 2.3e-43 146.1 0.0 4.5e-43 145.1 0.0 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Nab1 PF04902.12 OWF34080.1 - 0.00063 20.2 10.9 0.0028 18.1 10.9 2.0 1 1 0 1 1 1 1 Conserved region in Nab1 ORF6C PF10552.9 OWF34080.1 - 2.3 8.3 5.9 2.4 8.3 0.1 2.4 2 0 0 2 2 2 0 ORF6C domain PTN_MK_N PF05196.13 OWF34081.1 - 0.16 12.2 19.4 2.8 8.2 2.4 3.7 1 1 2 3 3 3 0 PTN/MK heparin-binding protein family, N-terminal domain DUF5615 PF18480.1 OWF34081.1 - 0.36 10.6 1.3 23 4.8 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5615) KH_1 PF00013.29 OWF34082.1 - 7.2e-54 179.5 16.9 1.2e-18 66.7 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OWF34082.1 - 9.8e-16 57.4 5.4 2.7e-05 23.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OWF34082.1 - 1.2e-07 31.5 1.3 0.23 11.3 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OWF34082.1 - 6.1e-06 26.2 6.5 0.68 10.1 0.3 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 OWF34082.1 - 3.7e-05 23.6 0.0 0.0035 17.3 0.0 2.9 3 0 0 3 3 3 1 KH-like RNA-binding domain Peptidase_M24 PF00557.24 OWF34083.1 - 1.8e-32 112.7 0.0 2.7e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 OWF34083.1 - 4.2e-30 105.0 0.0 9.4e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 OWF34083.1 - 2.6e-18 65.8 0.2 7.9e-18 64.3 0.2 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N_2 PF16189.5 OWF34084.1 - 2.4e-30 105.8 0.0 7.3e-30 104.2 0.0 1.9 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OWF34084.1 - 2.4e-27 96.0 0.0 5.6e-27 94.8 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 OWF34084.1 - 8.4e-16 57.8 0.3 1.8e-15 56.7 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OWF34084.1 - 2.5e-06 28.2 0.0 1.7e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain EF-hand_7 PF13499.6 OWF34085.1 - 3.3e-13 49.9 7.0 3.3e-06 27.4 1.8 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF34085.1 - 7e-10 38.0 7.1 0.0027 17.5 0.0 4.0 4 1 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OWF34085.1 - 2e-07 30.1 5.2 0.0018 17.7 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OWF34085.1 - 0.00049 19.9 9.8 0.01 15.7 0.6 3.4 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF34085.1 - 0.0018 17.7 0.0 0.0018 17.7 0.0 3.1 4 0 0 4 4 4 1 EF hand HALZ PF02183.18 OWF34086.1 - 2.9e-06 27.4 0.1 9.4 6.5 0.0 5.4 4 1 1 5 5 5 1 Homeobox associated leucine zipper Scaffolding_pro PF11418.8 OWF34086.1 - 0.03 14.9 8.2 4.4 7.9 1.0 4.0 2 1 2 4 4 4 0 Phi29 scaffolding protein GP52 PF17468.2 OWF34086.1 - 0.4 10.8 3.7 52 4.1 0.1 4.7 3 0 0 3 3 3 0 Phage gene product 52 TarH PF02203.15 OWF34086.1 - 0.72 9.8 18.9 8.3 6.3 3.5 3.8 2 1 2 4 4 4 0 Tar ligand binding domain homologue SHE3 PF17078.5 OWF34086.1 - 6.9 6.3 10.4 0.7 9.6 2.2 2.9 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 LRAT PF04970.13 OWF34464.1 - 1.9e-13 50.8 2.1 3.9e-12 46.6 2.1 2.3 1 1 0 1 1 1 1 Lecithin retinol acyltransferase DUF1287 PF06940.11 OWF34464.1 - 0.052 13.2 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Herpes_UL49_1 PF03117.14 OWF34464.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 UL49 family Gly-zipper_Omp PF13488.6 OWF34464.1 - 0.1 12.6 6.9 0.24 11.5 6.9 1.6 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 OWF34464.1 - 0.41 10.8 8.8 0.89 9.7 8.8 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF5043 PF16446.5 OWF34467.1 - 0.089 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) Chalcone_3 PF16036.5 OWF34468.1 - 0.011 15.8 0.4 0.98 9.5 0.1 2.4 1 1 0 2 2 2 0 Chalcone isomerase-like E7 PF00527.18 OWF34468.1 - 6 7.1 12.1 2.8 8.2 6.3 3.2 3 1 0 3 3 3 0 E7 protein, Early protein Mfp-3 PF04202.13 OWF34469.1 - 0.029 14.8 0.1 0.03 14.7 0.1 1.1 1 0 0 1 1 1 0 Foot protein 3 TA_inhibitor PF17574.2 OWF34469.1 - 0.066 13.2 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) TFR_dimer PF04253.15 OWF34470.1 - 1.2e-23 83.5 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Zona_pellucida PF00100.23 OWF34471.1 - 0.021 14.6 0.6 0.029 14.2 0.3 1.3 1 1 0 1 1 1 0 Zona pellucida-like domain TSP_1 PF00090.19 OWF34471.1 - 0.11 12.7 0.5 0.11 12.7 0.5 1.7 2 0 0 2 2 2 0 Thrombospondin type 1 domain FeThRed_B PF02943.15 OWF34473.1 - 0.077 13.0 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain C1q PF00386.21 OWF34475.1 - 6.6e-22 78.1 0.1 1.1e-21 77.4 0.1 1.4 1 0 0 1 1 1 1 C1q domain TLD PF07534.16 OWF34476.1 - 6.6e-14 52.3 0.7 8.8e-14 51.9 0.7 1.2 1 0 0 1 1 1 1 TLD CHCH PF06747.13 OWF34477.1 - 0.00011 22.3 3.6 0.00011 22.3 3.6 1.9 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 OWF34477.1 - 0.0003 20.7 1.4 0.00064 19.7 1.4 1.6 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GCK PF07802.11 OWF34477.1 - 0.0012 19.2 4.4 0.0018 18.6 4.4 1.4 1 0 0 1 1 1 1 GCK domain NLRC4_HD2 PF17776.1 OWF34477.1 - 0.0071 16.9 0.3 0.0092 16.5 0.3 1.2 1 0 0 1 1 1 1 NLRC4 helical domain HD2 BORCS6 PF10157.9 OWF34478.1 - 3e-23 82.7 0.3 3.5e-23 82.5 0.3 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 PLDc_2 PF13091.6 OWF34479.1 - 0.00018 21.4 0.2 0.00024 21.0 0.2 1.3 1 1 0 1 1 1 1 PLD-like domain DUF2286 PF10051.9 OWF34479.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) MtaB PF12176.8 OWF34479.1 - 0.096 11.5 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit BTB PF00651.31 OWF34481.1 - 3.4e-18 65.9 0.0 3.8e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain HEPN_DZIP3 PF18738.1 OWF34482.1 - 2.7e-31 108.3 0.0 3.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN Cornifin PF02389.15 OWF34483.1 - 0.039 14.1 0.1 0.14 12.3 0.1 1.9 1 1 0 1 1 1 0 Cornifin (SPRR) family DUF1989 PF09347.10 OWF34483.1 - 0.26 10.9 2.5 0.29 10.8 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1989) zf-RING_13 PF17977.1 OWF34483.1 - 0.37 10.9 3.9 42 4.4 0.0 3.6 1 1 3 4 4 4 0 RING/Ubox like zinc-binding domain SipA_VBS PF17985.1 OWF34484.1 - 0.028 14.3 4.9 72 3.6 0.0 5.9 7 0 0 7 7 7 0 SipA vinculin binding site Fibrinogen_C PF00147.18 OWF34486.1 - 6.1e-23 81.8 3.1 6.7e-23 81.6 3.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain C1q PF00386.21 OWF34487.1 - 7.9e-21 74.6 0.1 8.8e-21 74.4 0.1 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF34487.1 - 0.00013 21.9 0.1 0.00014 21.7 0.1 1.2 1 0 0 1 1 1 1 BclA C-terminal domain PPC PF04151.15 OWF34487.1 - 0.01 16.9 0.4 3.5 8.8 0.1 2.3 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain PA14 PF07691.12 OWF34487.1 - 0.058 13.2 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 PA14 domain DUF5122 PF17164.4 OWF34487.1 - 0.13 12.5 0.9 0.87 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller DUF5397 PF17375.2 OWF34488.1 - 0.035 13.8 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5397) Nbl1_Borealin_N PF10444.9 OWF34488.1 - 0.035 13.7 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal BIR PF00653.21 OWF34489.1 - 7.6e-13 48.9 0.7 3.1e-08 34.2 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.15 OWF34489.1 - 0.055 13.5 3.1 1.8 8.7 0.3 2.4 2 0 0 2 2 2 0 BED zinc finger BIR PF00653.21 OWF34490.1 - 7.6e-07 29.7 5.0 0.00022 21.8 0.3 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain DUF4304 PF14137.6 OWF34490.1 - 0.072 13.3 0.3 12 6.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) zf-C3HC4_3 PF13920.6 OWF34491.1 - 4.8e-10 39.1 8.0 6.3e-10 38.8 8.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF34491.1 - 0.0014 18.5 6.9 0.0022 17.8 6.9 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF34491.1 - 0.016 15.2 9.6 0.031 14.2 9.5 1.5 1 1 0 1 1 1 0 zinc-RING finger domain HALZ PF02183.18 OWF34491.1 - 0.074 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper TACC_C PF05010.14 OWF34492.1 - 0.0031 17.3 22.7 0.0031 17.3 22.7 2.3 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 OWF34492.1 - 0.0049 16.2 2.8 0.0049 16.2 2.8 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Yuri_gagarin PF15934.5 OWF34492.1 - 0.008 16.0 8.2 0.008 16.0 8.2 2.5 1 1 1 2 2 2 1 Yuri gagarin TolA_bind_tri PF16331.5 OWF34492.1 - 0.019 15.1 4.6 0.019 15.1 4.6 3.6 3 2 1 4 4 4 0 TolA binding protein trimerisation CALCOCO1 PF07888.11 OWF34492.1 - 0.091 11.6 33.7 0.94 8.3 30.4 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like PG_binding_4 PF12229.8 OWF34492.1 - 0.15 12.3 4.7 0.077 13.3 1.7 2.0 2 1 0 2 2 2 0 Putative peptidoglycan binding domain H-kinase_dim PF02895.14 OWF34492.1 - 0.16 12.4 10.4 1.9 8.9 0.1 3.3 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Tropomyosin_1 PF12718.7 OWF34492.1 - 0.16 12.1 40.8 0.3 11.2 9.9 3.5 1 1 2 3 3 3 0 Tropomyosin like Mod_r PF07200.13 OWF34492.1 - 0.18 11.9 33.8 0.081 13.0 7.2 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 OWF34492.1 - 0.52 10.7 34.1 0.39 11.2 10.0 2.1 1 1 1 2 2 2 0 Fez1 Baculo_PEP_C PF04513.12 OWF34492.1 - 1.4 9.0 11.4 0.84 9.7 1.0 3.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-H PF05837.12 OWF34492.1 - 1.4 9.4 32.5 0.24 11.8 8.2 3.3 1 1 2 3 3 3 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 OWF34492.1 - 1.8 8.7 34.4 0.093 12.8 2.2 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OWF34492.1 - 2.9 6.7 35.2 0.63 8.9 18.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein PhoU PF01895.19 OWF34492.1 - 3 8.4 10.3 10 6.6 0.1 4.3 1 1 3 4 4 4 0 PhoU domain Fib_alpha PF08702.10 OWF34492.1 - 3.2 7.9 29.8 0.092 12.9 12.3 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OWF34492.1 - 3.5 8.3 17.8 11 6.7 2.8 5.0 1 1 3 4 4 4 0 SlyX ATG16 PF08614.11 OWF34492.1 - 3.5 7.8 34.2 0.042 14.1 17.4 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Hrs_helical PF12210.8 OWF34492.1 - 5.9 7.5 16.9 0.19 12.3 6.5 3.3 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate HMMR_N PF15905.5 OWF34492.1 - 6.5 6.1 42.7 11 5.4 15.2 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 OWF34492.1 - 7.6 5.3 37.6 0.35 9.7 27.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TSC22 PF01166.18 OWF34492.1 - 8.1 6.9 18.4 4.5 7.7 0.0 5.1 3 2 0 4 4 4 0 TSC-22/dip/bun family AAA_13 PF13166.6 OWF34492.1 - 9.7 4.7 32.6 0.094 11.3 2.0 2.9 1 1 2 3 3 3 0 AAA domain TORC_N PF12884.7 OWF34493.1 - 0.0077 17.0 0.4 0.01 16.6 0.4 1.3 1 0 0 1 1 1 1 Transducer of regulated CREB activity, N terminus Peptidase_S64 PF08192.11 OWF34494.1 - 0.069 11.6 0.4 0.63 8.5 0.2 2.3 2 1 0 2 2 2 0 Peptidase family S64 Ank_2 PF12796.7 OWF34495.1 - 1.5e-18 67.2 0.3 1.1e-09 38.8 0.2 3.3 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF34495.1 - 2.1e-16 60.0 1.3 2.6e-07 31.0 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF34495.1 - 3.4e-14 51.5 1.3 0.01 16.3 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OWF34495.1 - 3.6e-11 43.1 0.3 0.0016 18.7 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF34495.1 - 1.1e-06 28.8 0.1 7.3 7.2 0.0 5.2 4 1 0 4 4 4 2 Ankyrin repeat PPR_2 PF13041.6 OWF34495.1 - 0.0097 16.1 0.1 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family DOT1 PF08123.13 OWF34496.1 - 0.15 11.6 0.9 0.15 11.5 0.1 1.4 2 0 0 2 2 2 0 Histone methylation protein DOT1 UCH PF00443.29 OWF34497.1 - 4.4e-32 111.6 0.8 6.5e-32 111.0 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF34497.1 - 1.8e-13 50.8 1.4 3.8e-12 46.4 1.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF473 PF04322.12 OWF34499.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF473) zf-C2H2_4 PF13894.6 OWF34501.1 - 0.028 15.2 7.8 4.6 8.3 4.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OWF34501.1 - 0.19 11.4 1.4 0.55 9.9 0.4 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 OWF34501.1 - 0.63 9.9 3.7 1.3 8.9 3.7 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF34501.1 - 0.85 10.2 8.9 6.4 7.4 5.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Trypsin_2 PF13365.6 OWF34502.1 - 0.068 14.1 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 Trypsin-like peptidase domain C1q PF00386.21 OWF34503.1 - 9e-15 55.0 0.2 9.9e-15 54.9 0.2 1.0 1 0 0 1 1 1 1 C1q domain Proteasome PF00227.26 OWF34503.1 - 0.076 12.5 0.1 0.61 9.5 0.1 1.9 1 1 1 2 2 2 0 Proteasome subunit PHR PF08005.12 OWF34504.1 - 1.4e-23 84.3 0.2 2.2e-23 83.6 0.2 1.3 1 0 0 1 1 1 1 PHR domain PHR PF08005.12 OWF34505.1 - 2.8e-31 109.3 2.8 2.8e-31 109.3 2.8 1.9 1 1 1 2 2 2 1 PHR domain DUF4082 PF13313.6 OWF34505.1 - 5.2e-06 26.6 0.1 8.4e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4082) C1q PF00386.21 OWF34510.1 - 1.3e-23 83.6 0.1 1.5e-23 83.4 0.1 1.0 1 0 0 1 1 1 1 C1q domain OCRE PF17780.1 OWF34510.1 - 0.053 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 OCRE domain zf-CCHC_2 PF13696.6 OWF34512.1 - 6.8e-05 22.6 2.1 0.00012 21.8 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OWF34512.1 - 0.027 14.6 3.7 0.041 14.0 3.7 1.3 1 0 0 1 1 1 0 Zinc knuckle ATP-synt_B PF00430.18 OWF34513.1 - 0.052 13.6 1.0 0.083 13.0 1.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RNA_helicase PF00910.22 OWF34515.1 - 0.0032 17.8 1.0 0.015 15.7 0.1 2.4 2 0 0 2 2 2 1 RNA helicase DUF5035 PF16438.5 OWF34515.1 - 0.02 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) DUF3047 PF11249.8 OWF34515.1 - 0.056 12.9 0.0 0.63 9.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3047) RuBisCO_small PF00101.20 OWF34515.1 - 0.071 13.1 0.8 0.24 11.4 0.8 1.9 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Uteroglobin PF01099.17 OWF34515.1 - 0.1 13.0 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 Uteroglobin family MFS_1 PF07690.16 OWF34516.1 - 5e-06 25.7 36.5 5e-06 25.7 36.5 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily LRR_8 PF13855.6 OWF34517.1 - 6.1e-37 125.2 56.4 4.3e-10 39.2 3.5 7.0 4 2 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OWF34517.1 - 8.9e-32 108.6 59.8 5.9e-08 32.9 2.6 8.8 4 2 7 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF34517.1 - 5.1e-10 38.5 54.2 2.8 8.8 0.1 13.4 12 2 1 13 13 13 7 Leucine Rich Repeat LRR_6 PF13516.6 OWF34517.1 - 0.0002 21.1 44.2 1.7 8.9 0.2 12.1 12 1 1 13 13 13 3 Leucine Rich repeat RsmF_methylt_CI PF17126.5 OWF34517.1 - 0.00033 20.6 2.5 15 5.8 0.0 5.4 5 1 0 5 5 5 2 RsmF rRNA methyltransferase first C-terminal domain SDP_N PF12278.8 OWF34517.1 - 3.9 7.6 9.1 6.6 6.9 0.6 2.3 2 0 0 2 2 2 0 Sex determination protein N terminal DED PF01335.21 OWF34519.1 - 6.1e-15 55.3 0.2 9.1e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 Death effector domain Ank_2 PF12796.7 OWF34520.1 - 4.4e-36 123.3 29.3 1.3e-07 32.1 1.7 6.9 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF34520.1 - 4.7e-23 81.3 15.5 7.5e-06 26.4 0.1 7.3 6 1 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF34520.1 - 5.3e-21 72.5 22.0 0.0031 17.9 0.0 11.5 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.6 OWF34520.1 - 1.2e-15 57.4 16.1 0.0014 18.8 0.1 8.0 7 2 2 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF34520.1 - 5e-12 45.7 18.0 0.072 13.6 0.0 10.2 12 0 0 12 12 12 3 Ankyrin repeat DUF3445 PF11927.8 OWF34520.1 - 5.6e-07 29.4 12.6 1.8 8.1 0.1 5.7 1 1 5 6 6 6 4 Protein of unknown function (DUF3445) GST_N_3 PF13417.6 OWF34520.1 - 0.00057 20.2 0.2 6 7.3 0.0 4.5 4 1 1 5 5 5 1 Glutathione S-transferase, N-terminal domain CgtA PF06306.11 OWF34520.1 - 0.0008 18.9 4.7 5 6.5 0.0 5.0 5 1 1 6 6 6 2 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) DUF468 PF04318.12 OWF34520.1 - 0.0026 18.4 9.4 1.2 9.9 0.0 4.7 3 2 1 4 4 4 1 Protein of unknown function (DUF468) TGT_C1 PF14809.6 OWF34520.1 - 0.0027 18.0 0.0 17 5.8 0.0 4.2 4 0 0 4 4 4 0 C1 domain of tRNA-guanine transglycosylase dimerisation FtsJ PF01728.19 OWF34520.1 - 0.0059 16.7 3.1 0.027 14.6 0.1 3.0 3 1 0 3 3 3 1 FtsJ-like methyltransferase VWA_3_C PF18571.1 OWF34520.1 - 0.0064 16.3 0.0 4.7 7.2 0.0 4.2 5 0 0 5 5 5 1 von Willebrand factor type A C-terminal domain His_Me_b4a2 PF18275.1 OWF34520.1 - 0.039 14.0 2.6 12 6.1 0.1 3.9 4 0 0 4 4 4 0 His-Me finger endonuclease beta4-alpha2 domain DUF3019 PF11456.8 OWF34520.1 - 0.33 11.5 22.9 4.3 7.9 0.7 5.7 2 1 3 6 6 6 0 Protein of unknown function (DUF3019) UL40 PF10682.9 OWF34521.1 - 0.093 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Nas2_N PF18265.1 OWF34523.1 - 0.18 11.8 1.5 5.2 7.1 0.1 2.7 1 1 1 2 2 2 0 Nas2 N_terminal domain Kazal_2 PF07648.15 OWF34524.1 - 3.1e-16 59.2 14.2 1e-11 44.7 5.0 2.1 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF34524.1 - 1.6e-13 50.5 12.1 1e-10 41.5 5.2 2.4 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Ephrin_rec_like PF07699.13 OWF34525.1 - 1.5e-18 66.3 23.9 4.2e-10 39.2 2.7 4.3 2 1 1 3 3 3 3 Putative ephrin-receptor like DUF2318 PF10080.9 OWF34525.1 - 0.048 13.8 9.3 0.13 12.4 1.9 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) FhuF_C PF11575.8 OWF34525.1 - 0.39 10.7 7.3 4.2 7.4 0.3 3.8 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Spp-24 PF07448.11 OWF34526.1 - 0.1 12.8 1.0 0.2 11.9 1.0 1.5 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Ac81 PF05820.11 OWF34526.1 - 0.25 10.9 0.6 0.47 10.0 0.6 1.3 1 0 0 1 1 1 0 Baculoviridae AC81 TMEM154 PF15102.6 OWF34526.1 - 1 9.2 7.9 2.2 8.2 7.9 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF2574 PF10836.8 OWF34528.1 - 0.067 13.1 2.6 0.077 12.9 1.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) HYR PF02494.16 OWF34529.1 - 1.1e-06 28.8 1.6 2.4e-06 27.8 1.6 1.6 1 0 0 1 1 1 1 HYR domain EGF_CA PF07645.15 OWF34529.1 - 0.0047 17.1 1.1 0.0047 17.1 1.1 2.4 2 1 0 2 2 2 1 Calcium-binding EGF domain 7tm_1 PF00001.21 OWF34531.1 - 1.5e-18 67.1 18.9 1.9e-18 66.8 18.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF34531.1 - 0.0022 17.7 12.7 0.0022 17.7 12.7 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx FAM195 PF14799.6 OWF34532.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 FAM195 family Microtub_bind PF13931.6 OWF34533.1 - 0.004 17.5 0.9 0.0046 17.3 0.9 1.1 1 0 0 1 1 1 1 Kinesin-associated microtubule-binding FAM124 PF15067.6 OWF34534.1 - 1.8e-87 292.9 0.3 2.2e-87 292.6 0.3 1.1 1 0 0 1 1 1 1 FAM124 family BAAT_C PF08840.11 OWF34535.1 - 1.3e-38 133.1 0.0 1.1e-37 130.0 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 OWF34535.1 - 7.1e-33 113.4 0.0 1e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 OWF34535.1 - 8.6e-07 28.7 0.0 0.075 12.6 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OWF34535.1 - 0.011 15.2 0.0 0.029 13.9 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family QVR PF17064.5 OWF34536.1 - 0.011 16.0 0.3 0.012 15.8 0.3 1.1 1 0 0 1 1 1 0 Sleepless protein TROVE PF05731.11 OWF34537.1 - 1e-21 77.5 1.2 9.1e-21 74.4 1.2 1.9 1 1 0 1 1 1 1 TROVE domain Fibrinogen_C PF00147.18 OWF34537.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain AMP-binding_C PF13193.6 OWF34538.1 - 2.9e-19 69.8 0.2 4.2e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF34538.1 - 6.3e-12 44.8 0.4 7.9e-12 44.5 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cupin_8 PF13621.6 OWF34539.1 - 1.1e-09 38.4 1.1 2.9e-08 33.7 0.3 2.3 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 OWF34539.1 - 6.9e-07 29.0 0.7 0.00078 19.0 0.1 2.1 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 OWF34539.1 - 0.0035 17.7 0.1 0.018 15.5 0.0 2.2 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OWF34539.1 - 0.055 13.2 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Sushi PF00084.20 OWF34540.1 - 1.9e-124 406.2 80.6 1.7e-11 44.5 0.3 13.4 14 0 0 14 14 14 13 Sushi repeat (SCR repeat) HRM PF02793.22 OWF34540.1 - 2.8e-09 37.1 60.5 0.2 12.0 0.5 12.6 12 1 1 13 13 13 10 Hormone receptor domain ATG2_CAD PF13329.6 OWF34540.1 - 0.08 12.7 0.0 60 3.3 0.0 3.5 3 0 0 3 3 3 0 Autophagy-related protein 2 CAD motif SSF PF00474.17 OWF34541.1 - 5.4e-17 61.8 5.9 7.1e-17 61.4 5.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Fam20C PF06702.12 OWF34542.1 - 7.1e-39 133.9 0.8 7.8e-39 133.8 0.8 1.0 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 EF-hand_7 PF13499.6 OWF34543.1 - 7e-25 87.3 4.7 9.9e-14 51.6 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF34543.1 - 2.6e-23 79.8 11.7 1.1e-09 37.1 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF34543.1 - 2.4e-20 70.7 8.3 1.6e-09 36.9 0.1 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF34543.1 - 8.2e-16 57.6 10.0 1.4e-07 31.2 1.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF34543.1 - 3e-14 51.8 1.1 1e-06 27.9 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 OWF34543.1 - 5.2e-09 36.3 0.4 2.4e-07 31.0 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.13 OWF34543.1 - 0.0016 18.4 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 OWF34543.1 - 0.0017 18.3 2.4 2.3 8.2 0.1 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF34543.1 - 0.011 15.6 0.1 2.9 7.8 0.0 2.5 2 1 0 2 2 2 0 Caleosin related protein EFhand_Ca_insen PF08726.10 OWF34543.1 - 0.013 15.6 0.4 2.4 8.3 0.1 2.5 2 1 0 2 2 2 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 OWF34543.1 - 0.035 14.4 1.6 3.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 OWF34543.1 - 0.08 13.3 0.2 0.32 11.4 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain JmjC PF02373.22 OWF34544.1 - 3e-43 146.9 1.3 5.1e-43 146.1 1.3 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 OWF34544.1 - 2.7e-18 66.1 13.1 2.7e-18 66.1 13.1 2.9 2 1 0 2 2 2 1 C5HC2 zinc finger 7tm_1 PF00001.21 OWF34545.1 - 2.3e-32 112.4 17.5 3.3e-32 111.9 17.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-C4 PF00105.18 OWF34547.1 - 1.5e-07 31.8 0.2 1.7e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SerH PF06873.11 OWF34547.1 - 0.03 13.1 0.3 0.035 12.9 0.3 1.0 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH Peptidase_M1_N PF17900.1 OWF34548.1 - 9.7e-16 58.5 0.1 1.3e-15 58.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain EF-hand_7 PF13499.6 OWF34549.1 - 2.7e-20 72.6 5.3 2.1e-13 50.5 1.8 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF34549.1 - 1.1e-19 68.4 14.7 7.6e-08 31.4 1.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF34549.1 - 6.6e-17 59.9 9.4 3.2e-05 23.5 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF34549.1 - 1.3e-15 56.1 10.2 1.4e-05 24.3 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF34549.1 - 4.7e-15 55.2 8.2 8.1e-06 25.6 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF34549.1 - 2.3e-06 27.9 1.0 0.00028 21.2 1.0 3.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF34549.1 - 0.026 14.5 0.9 0.66 10.0 0.0 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF34549.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 OWF34549.1 - 0.055 13.7 0.6 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_2 PF09068.11 OWF34549.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 EF hand Fringe PF02434.16 OWF34550.1 - 6.4e-15 55.3 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Fringe-like CHGN PF05679.16 OWF34550.1 - 1.4e-11 43.9 0.4 2.1e-11 43.4 0.4 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Galactosyl_T PF01762.21 OWF34550.1 - 0.011 15.6 0.1 0.025 14.4 0.1 1.7 1 1 0 1 1 1 0 Galactosyltransferase DUF4830 PF16112.5 OWF34550.1 - 0.066 13.7 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4830) Neur_chan_LBD PF02931.23 OWF34551.1 - 2e-38 132.0 0.9 2e-38 132.0 0.9 1.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF34551.1 - 9.8e-14 52.0 14.8 5e-13 49.7 9.1 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Fibrinogen_C PF00147.18 OWF34553.1 - 5.1e-60 203.0 10.8 6.1e-60 202.8 10.8 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Sugar_tr PF00083.24 OWF34554.1 - 4e-21 75.4 3.7 4.9e-21 75.1 3.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF34554.1 - 3.2e-14 52.6 16.0 1.2e-08 34.3 9.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SNAP PF14938.6 OWF34555.1 - 3.5e-53 180.9 5.5 4e-53 180.7 5.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF2150 PF09920.9 OWF34555.1 - 0.016 15.2 0.1 0.035 14.1 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_8 PF13181.6 OWF34555.1 - 0.028 14.6 0.5 0.11 12.8 0.5 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF34555.1 - 0.05 13.6 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF410 PF04190.13 OWF34555.1 - 0.081 12.7 1.9 0.23 11.2 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF410) TPR_2 PF07719.17 OWF34555.1 - 0.16 12.1 1.1 0.47 10.7 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 OWF34556.1 - 6.6e-14 52.1 3.9 1.5e-06 28.8 0.1 4.3 3 1 1 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF34556.1 - 2.7e-05 24.4 0.0 0.11 12.8 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 OWF34558.1 - 4e-29 100.4 0.1 4.1e-20 71.5 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein KdpA PF03814.15 OWF34558.1 - 0.14 10.3 0.0 0.17 10.0 0.0 1.0 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit MFS_1 PF07690.16 OWF34559.1 - 1.3e-06 27.6 13.7 6.1e-06 25.4 14.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UDPGP PF01704.18 OWF34560.1 - 2.5e-60 204.3 0.1 2.9e-60 204.1 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DSPc PF00782.20 OWF34561.1 - 2.1e-29 102.0 0.1 2.5e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF34561.1 - 0.028 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF34561.1 - 0.084 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate ELO PF01151.18 OWF34562.1 - 1.6e-40 139.2 22.6 3.7e-40 138.0 22.6 1.5 1 1 0 1 1 1 1 GNS1/SUR4 family AP-5_subunit_s1 PF15001.6 OWF34563.1 - 1.7e-58 197.8 0.9 1.9e-58 197.7 0.9 1.0 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 VWA PF00092.28 OWF34564.1 - 2.1e-18 67.2 1.8 2.2e-17 63.8 0.6 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF34564.1 - 1.7e-15 57.3 0.0 2.9e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF34564.1 - 3.5e-10 40.5 0.3 4e-09 37.1 0.1 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain 7tm_1 PF00001.21 OWF34565.1 - 6.3e-49 166.7 10.6 8.6e-49 166.2 10.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF34565.1 - 6e-10 38.9 11.7 8.6e-10 38.4 11.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF34565.1 - 1.4e-06 28.3 13.2 2.4e-06 27.5 13.2 1.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF34565.1 - 3.2e-06 27.0 16.6 4.5e-06 26.5 16.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF34565.1 - 0.01 15.2 17.4 0.015 14.6 17.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw TMEM189_B_dmain PF10520.9 OWF34565.1 - 2.6 8.1 4.7 4.9 7.3 0.6 2.2 1 1 1 2 2 2 0 B domain of TMEM189, localisation domain Pkinase PF00069.25 OWF34567.1 - 2.3e-40 138.6 0.3 2.9e-40 138.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34567.1 - 1.6e-25 89.9 0.6 2.2e-25 89.4 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OWF34567.1 - 0.0077 15.8 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OWF34567.1 - 0.018 14.4 0.1 0.024 14.0 0.1 1.3 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OWF34567.1 - 0.033 13.0 0.1 0.085 11.6 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OWF34567.1 - 0.048 13.0 0.5 0.11 11.8 0.5 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF34567.1 - 0.074 13.0 0.1 1.1 9.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rhomboid PF01694.22 OWF34568.1 - 1.9e-29 102.6 11.4 1.9e-29 102.6 11.4 1.3 2 0 0 2 2 2 1 Rhomboid family DUF4203 PF13886.6 OWF34568.1 - 0.037 13.7 15.6 0.46 10.1 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) SNF2_N PF00176.23 OWF34569.1 - 1.5e-68 231.1 0.0 2e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 OWF34569.1 - 0.0002 21.4 0.0 0.00058 19.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OWF34569.1 - 0.0014 18.3 0.0 0.0041 16.8 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase VWA PF00092.28 OWF34570.1 - 4.9e-33 114.8 0.5 5.7e-33 114.6 0.5 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF34570.1 - 2.5e-11 44.2 0.0 4.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 OWF34570.1 - 0.00023 20.7 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Copine VWA_3 PF13768.6 OWF34570.1 - 0.0086 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain SIS_2 PF13580.6 OWF34570.1 - 0.092 12.8 0.1 0.22 11.6 0.1 1.6 1 1 0 1 1 1 0 SIS domain vWA-TerF-like PF10138.9 OWF34570.1 - 0.18 11.9 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus adh_short PF00106.25 OWF34571.1 - 6.7e-41 139.9 0.1 8.3e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF34571.1 - 4.6e-39 134.4 0.0 5.7e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF34571.1 - 4.1e-11 43.1 0.0 5.2e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 KR domain IGFL PF14653.6 OWF34573.1 - 0.16 12.0 0.2 0.16 12.0 0.2 4.9 2 1 3 5 5 5 0 Insulin growth factor-like family IPP-2 PF04979.14 OWF34574.1 - 2.6e-22 80.0 6.5 2.9e-22 79.8 6.5 1.0 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) EF-hand_6 PF13405.6 OWF34575.1 - 8.6e-10 37.8 3.5 1e-05 25.1 0.3 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OWF34575.1 - 1.2e-09 38.4 0.7 8.1e-05 23.0 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF34575.1 - 9e-08 31.3 3.6 5.3e-07 28.9 0.5 2.7 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 OWF34575.1 - 1.1e-07 30.8 8.5 3.7e-06 26.1 1.1 3.5 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OWF34575.1 - 8e-07 28.8 1.7 0.00096 19.0 0.8 3.4 2 1 0 2 2 2 2 EF-hand domain pair YafQ_toxin PF15738.5 OWF34575.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ QueF PF14489.6 OWF34575.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein Dockerin_1 PF00404.18 OWF34575.1 - 0.14 12.4 0.0 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 Dockerin type I domain Ras PF00071.22 OWF34576.1 - 1.3e-18 67.1 0.0 1.8e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Lipin_mid PF16876.5 OWF34576.1 - 0.11 12.7 0.2 0.31 11.2 0.1 1.8 1 1 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Ank_4 PF13637.6 OWF34577.1 - 6.8e-15 55.2 0.1 8.6e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF34577.1 - 1.1e-11 44.8 0.7 8.3e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF34577.1 - 2.3e-10 39.8 0.3 1.6e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OWF34577.1 - 2.5e-10 40.8 0.0 3.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF34577.1 - 1.3e-09 38.0 0.4 1.9e-05 24.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat GILT PF03227.16 OWF34577.1 - 0.082 13.2 0.0 0.099 12.9 0.0 1.1 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Arf PF00025.21 OWF34578.1 - 1.1e-14 54.2 0.0 1.3e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Arrestin_C PF02752.22 OWF34579.1 - 1.6e-17 64.2 0.0 1.1e-16 61.5 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF34579.1 - 6.5e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OWF34579.1 - 0.003 16.8 0.0 0.049 12.8 0.0 2.1 2 0 0 2 2 2 1 Rgp1 YicC_N PF03755.13 OWF34579.1 - 0.072 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 YicC-like family, N-terminal region Hormone_recep PF00104.30 OWF34580.1 - 8.6e-17 61.4 0.2 1.3e-16 60.8 0.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor His_Phos_2 PF00328.22 OWF34581.1 - 3.3e-09 36.6 0.0 5.8e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ABC_membrane PF00664.23 OWF34582.1 - 1.3e-30 107.0 8.6 2.6e-30 106.0 8.6 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region Skp1 PF01466.19 OWF34583.1 - 7.7e-30 102.8 0.6 1e-29 102.4 0.6 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain 2-oxoacid_dh PF00198.23 OWF34584.1 - 3e-24 85.8 0.0 3.2e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Kelch_4 PF13418.6 OWF34586.1 - 2.4e-27 94.7 4.1 3.9e-08 33.2 0.0 4.4 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF34586.1 - 7.4e-22 76.9 2.4 1.9e-05 24.5 0.1 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 OWF34586.1 - 9.6e-22 76.8 9.5 3.8e-06 27.1 0.0 5.0 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OWF34586.1 - 1.5e-18 66.1 3.9 0.0013 18.3 0.0 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 OWF34586.1 - 4.7e-17 61.6 7.8 0.00013 22.1 0.1 4.3 3 1 1 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OWF34586.1 - 2.6e-16 58.9 9.1 0.00016 21.5 0.9 4.2 4 0 0 4 4 4 4 Kelch motif DUF4605 PF15378.6 OWF34587.1 - 1.9e-21 75.7 2.7 2.5e-21 75.3 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) MFS_1 PF07690.16 OWF34588.1 - 4.1e-18 65.4 17.7 4.2e-12 45.7 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 OWF34588.1 - 0.021 13.9 6.2 0.028 13.4 6.2 1.2 1 0 0 1 1 1 0 PUCC protein Forkhead PF00250.18 OWF34589.1 - 2.4e-20 72.6 0.7 3.9e-20 71.9 0.7 1.3 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 OWF34589.1 - 0.015 15.6 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family EF-hand_1 PF00036.32 OWF34590.1 - 4.2e-22 76.0 3.2 2e-07 30.0 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OWF34590.1 - 4.2e-20 72.0 0.1 8.8e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF34590.1 - 1.4e-16 60.0 4.0 3.7e-07 29.9 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF34590.1 - 3.5e-15 54.6 5.0 4.7e-08 32.3 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OWF34590.1 - 2.6e-14 52.0 3.9 7e-06 25.3 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OWF34590.1 - 2.4e-05 24.5 0.0 0.0091 16.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF34590.1 - 0.00021 21.2 1.3 0.25 11.3 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OWF34590.1 - 0.0043 17.9 0.0 0.0086 16.9 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF34590.1 - 0.035 14.4 0.0 0.21 11.9 0.0 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF34590.1 - 0.043 14.0 4.0 0.084 13.1 0.1 2.6 2 1 1 3 3 3 0 Dockerin type I domain DUF5580 PF17743.1 OWF34590.1 - 0.16 10.5 0.0 0.16 10.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SNF PF00209.18 OWF34591.1 - 2.1e-39 135.6 6.0 2.3e-39 135.5 6.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ras PF00071.22 OWF34592.1 - 0.022 14.3 0.0 0.042 13.5 0.0 1.4 1 1 0 1 1 1 0 Ras family EF-hand_6 PF13405.6 OWF34593.1 - 3.6e-09 35.8 2.2 8.5e-06 25.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF34593.1 - 1.1e-08 35.4 0.8 1.1e-08 35.4 0.8 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF34593.1 - 7.1e-05 22.1 0.0 7.1e-05 22.1 0.0 3.7 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 OWF34593.1 - 0.00011 22.0 2.9 0.00011 21.9 0.3 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_11 PF08976.11 OWF34593.1 - 0.0063 17.4 0.0 0.0096 16.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 OWF34593.1 - 0.029 14.3 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OWF34593.1 - 0.31 10.6 2.5 2 8.0 0.0 2.9 3 0 0 3 3 3 0 EF hand MIG-14_Wnt-bd PF06664.12 OWF34594.1 - 5.1e-70 236.0 21.8 5.7e-70 235.8 21.8 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion 7tm_3 PF00003.22 OWF34594.1 - 0.021 14.6 12.6 0.031 14.0 12.6 1.4 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR MnhB PF04039.13 OWF34594.1 - 0.25 11.7 6.9 0.39 11.0 0.5 2.3 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Use1 PF09753.9 OWF34595.1 - 1e-27 97.4 6.5 1.2e-27 97.3 6.5 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Rhabdo_glycop PF00974.18 OWF34595.1 - 0.015 13.8 0.1 0.016 13.7 0.1 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein MRAP PF15183.6 OWF34595.1 - 0.033 14.1 0.2 0.045 13.7 0.2 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF2207 PF09972.9 OWF34595.1 - 1.7 7.3 4.6 2.3 6.9 4.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) WD40 PF00400.32 OWF34596.1 - 0.00018 22.2 0.5 0.32 12.0 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF34596.1 - 0.0043 17.3 0.0 3.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OWF34596.1 - 0.14 10.2 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 IKI3 family MOSC_N PF03476.16 OWF34597.1 - 1e-24 86.7 0.0 1.3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Sulfotransfer_2 PF03567.14 OWF34598.1 - 3e-31 109.3 4.8 3.9e-29 102.3 0.4 2.2 1 1 0 2 2 2 2 Sulfotransferase family SBF PF01758.16 OWF34599.1 - 4.6e-36 124.3 11.5 5.9e-36 124.0 11.5 1.1 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 OWF34599.1 - 7.1e-08 32.1 8.2 8.9e-08 31.8 8.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) zf-C3HC4_4 PF15227.6 OWF34600.1 - 0.0015 18.6 36.9 0.1 12.8 6.7 6.0 1 1 4 5 5 5 4 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF34600.1 - 1.4 8.8 35.0 5.2 7.0 6.5 4.4 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) AIG1 PF04548.16 OWF34601.1 - 2.9e-62 209.8 0.8 3.7e-62 209.4 0.2 1.4 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF34601.1 - 9.2e-08 32.2 0.0 2.8e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF34601.1 - 0.00011 22.2 3.0 0.00017 21.5 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 OWF34601.1 - 0.00042 19.9 0.0 0.00083 18.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 OWF34601.1 - 0.013 16.0 6.4 0.017 15.6 0.4 2.4 2 1 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 OWF34601.1 - 0.022 14.5 0.2 0.69 9.7 0.1 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FTA4 PF13093.6 OWF34601.1 - 0.027 14.4 1.3 0.04 13.8 1.3 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Polysacc_deac_1 PF01522.21 OWF34601.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide deacetylase Borrelia_P83 PF05262.11 OWF34601.1 - 0.44 9.0 6.8 0.57 8.6 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_22 PF13401.6 OWF34601.1 - 0.79 10.0 3.4 0.79 10.0 0.2 2.5 2 2 0 2 2 2 0 AAA domain ArAE_2_N PF10337.9 OWF34601.1 - 0.97 8.4 3.4 1.5 7.8 3.4 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal AAA_24 PF13479.6 OWF34601.1 - 1.2 8.8 4.4 0.86 9.3 0.3 2.4 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OWF34601.1 - 2.8 7.9 14.0 2.4 8.2 0.6 3.8 1 1 2 4 4 4 0 Dynamin family CCDC-167 PF15188.6 OWF34601.1 - 3.1 8.2 17.2 10 6.6 0.2 3.5 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 WD40 PF00400.32 OWF34602.1 - 1.4e-13 51.0 3.0 0.0001 23.0 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF34602.1 - 3.9e-06 27.1 0.0 0.029 14.7 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF34603.1 - 5.1e-13 49.3 0.0 1.1e-05 26.1 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF34603.1 - 0.00055 20.2 0.0 0.026 14.8 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain UbiA PF01040.18 OWF34604.1 - 6.4e-37 127.2 11.9 1.1e-36 126.5 11.9 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family TMEM208_SND2 PF05620.11 OWF34604.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 HEAT_EZ PF13513.6 OWF34605.1 - 0.0068 16.9 0.2 0.075 13.6 0.0 2.0 1 1 1 2 2 2 1 HEAT-like repeat 7tm_1 PF00001.21 OWF34606.1 - 4.1e-31 108.3 10.1 5.6e-31 107.8 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF34606.1 - 1.2e-09 38.2 12.1 1.5e-09 37.9 12.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF34606.1 - 8.2e-08 31.9 4.1 1.1e-07 31.5 4.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Tetraspanin PF00335.20 OWF34606.1 - 0.013 15.2 2.4 0.016 14.9 2.4 1.3 1 1 0 1 1 1 0 Tetraspanin family 7tm_4 PF13853.6 OWF34606.1 - 0.092 12.5 6.2 0.12 12.1 6.2 1.1 1 0 0 1 1 1 0 Olfactory receptor Ctr PF04145.15 OWF34607.1 - 1.7e-13 51.5 6.5 2.3e-13 51.0 6.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Ca_hom_mod PF14798.6 OWF34607.1 - 0.021 14.0 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator 7tm_1 PF00001.21 OWF34608.1 - 9.1e-06 25.2 2.1 1.1e-05 24.9 1.8 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 OWF34608.1 - 0.019 14.3 5.1 0.017 14.5 3.7 1.6 1 1 1 2 2 2 0 7 transmembrane receptor (Secretin family) STE3 PF02076.15 OWF34608.1 - 0.024 13.8 7.0 0.062 12.5 5.9 1.8 1 1 0 1 1 1 0 Pheromone A receptor SID-1_RNA_chan PF13965.6 OWF34608.1 - 0.79 8.1 6.2 1.9 6.8 0.3 2.1 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 WD40 PF00400.32 OWF34610.1 - 0.047 14.6 1.8 0.24 12.4 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat NHL PF01436.21 OWF34611.1 - 1e-08 34.8 1.4 0.27 11.3 0.0 4.7 4 0 0 4 4 4 2 NHL repeat zf-C3HC4 PF00097.25 OWF34611.1 - 3.4e-08 33.2 15.4 3.4e-08 33.2 15.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF34611.1 - 5.8e-08 32.9 15.5 5.8e-08 32.9 15.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF34611.1 - 3.3e-07 30.2 13.3 3.3e-07 30.2 13.3 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF34611.1 - 8.4e-07 29.1 13.9 8.4e-07 29.1 13.9 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF34611.1 - 2.5e-05 24.0 12.6 2.5e-05 24.0 12.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF34611.1 - 5.8e-05 23.0 14.9 5.8e-05 23.0 14.9 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF34611.1 - 8.8e-05 22.3 14.8 8.8e-05 22.3 14.8 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OWF34611.1 - 0.0043 17.1 0.0 0.44 10.9 0.0 3.3 3 0 0 3 3 3 1 Two component regulator propeller SNF PF00209.18 OWF34612.1 - 5.4e-18 65.0 0.3 7.2e-18 64.6 0.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family NUDIX PF00293.28 OWF34613.1 - 5.3e-14 52.4 0.1 6.3e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain ANF_receptor PF01094.28 OWF34614.1 - 1e-30 107.1 0.0 2.5e-30 105.8 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF34614.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein POPLD PF08170.12 OWF34615.1 - 6.2e-29 100.2 1.4 1e-28 99.5 0.1 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain AAA_21 PF13304.6 OWF34616.1 - 0.051 13.4 0.5 0.061 13.1 0.5 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SYCP2_SLD PF18584.1 OWF34616.1 - 0.13 12.5 2.3 0.37 11.0 0.6 2.1 2 0 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain DUF3629 PF12302.8 OWF34616.1 - 7.8 5.9 14.2 37 3.6 13.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3629) Fibrinogen_C PF00147.18 OWF34617.1 - 4.5e-10 39.7 1.5 4.5e-10 39.7 1.5 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DpaA_N PF16924.5 OWF34618.1 - 0.25 11.5 0.3 1.6 8.8 0.0 2.3 3 0 0 3 3 3 0 Dipicolinate synthase subunit A N-terminal domain Transmemb_17 PF09799.9 OWF34619.1 - 2.7e-06 27.9 1.8 4.6e-06 27.2 1.8 1.4 1 0 0 1 1 1 1 Predicted membrane protein VWA PF00092.28 OWF34620.1 - 1.8e-40 139.0 0.0 2.1e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF34620.1 - 1.2e-13 51.6 0.0 1.9e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF34620.1 - 3.9e-07 30.2 0.0 5.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain NSs PF11073.8 OWF34620.1 - 0.094 12.1 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Rift valley fever virus non structural protein (NSs) like DGCR6 PF07324.11 OWF34621.1 - 2.2e-36 125.3 2.0 2.3e-36 125.2 2.0 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein WD40 PF00400.32 OWF34622.1 - 0.0002 22.1 7.9 0.047 14.6 0.1 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF34622.1 - 0.076 13.3 0.0 0.32 11.3 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Galactosyl_T PF01762.21 OWF34623.1 - 1.1e-53 182.0 0.2 1.5e-53 181.5 0.2 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF34623.1 - 4.7e-05 22.9 0.5 0.00011 21.7 0.5 1.6 1 1 0 1 1 1 1 Fringe-like Calponin PF00402.18 OWF34624.1 - 1.1e-09 37.7 0.3 1.8e-09 37.1 0.3 1.4 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 OWF34624.1 - 8.1e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain SASRP1 PF15160.6 OWF34625.1 - 3.4e-10 40.0 0.0 3.6e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated serine-rich protein 1 C1q PF00386.21 OWF34626.1 - 1.5e-19 70.4 0.1 1.8e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 C1q domain CECR6_TMEM121 PF14997.6 OWF34627.1 - 2.3e-42 145.1 2.8 2.3e-42 145.1 2.8 1.4 2 0 0 2 2 2 1 CECR6/TMEM121 family Cyt_c_ox_IV PF12270.8 OWF34627.1 - 2.3e-05 24.5 0.5 0.00023 21.3 0.3 2.2 1 1 1 2 2 2 1 Cytochrome c oxidase subunit IV DUF2339 PF10101.9 OWF34627.1 - 0.0006 18.5 0.4 0.00077 18.2 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) FeoB_associated PF12669.7 OWF34627.1 - 0.0021 18.4 3.3 0.14 12.6 0.0 4.0 4 0 0 4 4 4 1 FeoB-associated Cys-rich membrane protein ECH_1 PF00378.20 OWF34628.1 - 2.5e-14 53.2 0.8 3e-14 52.9 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Death PF00531.22 OWF34629.1 - 1.8e-06 28.0 0.1 1.2e-05 25.4 0.1 1.9 1 1 0 1 1 1 1 Death domain Arf PF00025.21 OWF34630.1 - 1.3e-62 210.3 0.1 1.5e-62 210.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF34630.1 - 4.5e-13 49.5 0.0 6.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF34630.1 - 1e-12 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF34630.1 - 1.3e-10 41.0 0.2 2.5e-10 40.1 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF34630.1 - 1.9e-06 27.4 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF34630.1 - 5.4e-06 25.8 0.1 0.0047 16.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF34630.1 - 0.00053 20.1 0.1 0.00092 19.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 OWF34630.1 - 0.045 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SpoOE-like PF09388.10 OWF34630.1 - 0.053 13.4 0.3 0.053 13.4 0.3 1.7 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein zf-B_box PF00643.24 OWF34631.1 - 4.9e-13 49.0 25.3 3.6e-08 33.4 6.9 2.7 3 0 0 3 3 3 2 B-box zinc finger CEBP_ZZ PF16366.5 OWF34631.1 - 0.0011 19.1 11.4 0.059 13.6 1.4 2.7 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1664 PF07889.12 OWF34631.1 - 5.6 7.0 8.0 3.9 7.5 1.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FYVE PF01363.21 OWF34631.1 - 8.9 6.5 16.7 14 6.0 2.9 2.7 1 1 0 2 2 2 0 FYVE zinc finger AAA_5 PF07728.14 OWF34632.1 - 0.005 16.9 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2315 PF10231.9 OWF34633.1 - 1.4e-22 80.1 0.9 1.7e-22 79.8 0.9 1.1 1 0 0 1 1 1 1 Apoptogenic protein 1 DUF223 PF02721.14 OWF34634.1 - 4.8 7.6 8.8 10 6.5 3.6 3.6 2 1 1 3 3 3 0 Domain of unknown function DUF223 Folate_rec PF03024.14 OWF34636.1 - 3.9e-16 59.4 12.9 7.2e-16 58.5 13.0 1.4 1 1 0 1 1 1 1 Folate receptor family PRA-PH PF01503.17 OWF34636.1 - 0.00044 20.6 0.0 0.00068 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase DUF3445 PF11927.8 OWF34636.1 - 0.17 11.5 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) 7tm_3 PF00003.22 OWF34637.1 - 1.7e-19 70.5 8.9 1.8e-19 70.4 8.9 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF5391 PF17369.2 OWF34637.1 - 0.019 15.0 4.7 0.024 14.7 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5391) NPR3 PF03666.13 OWF34638.1 - 2.8 6.6 8.5 3.2 6.4 8.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AMP-binding_C PF13193.6 OWF34639.1 - 0.061 14.3 0.0 0.087 13.8 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain BIR PF00653.21 OWF34641.1 - 1.3e-29 102.6 6.7 3.4e-21 75.7 0.6 3.5 3 0 0 3 3 3 3 Inhibitor of Apoptosis domain UCH PF00443.29 OWF34642.1 - 3.5e-29 102.1 0.0 7.8e-29 100.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF34642.1 - 2.9e-10 40.2 3.1 8.1e-09 35.5 3.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Macro PF01661.21 OWF34643.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Macro domain DUF3487 PF11990.8 OWF34643.1 - 0.15 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Sulfotransfer_1 PF00685.27 OWF34644.1 - 1.7e-41 142.5 3.0 2e-41 142.3 3.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF34644.1 - 4.2e-05 24.0 0.0 6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_C10 PF01640.17 OWF34644.1 - 0.083 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase C10 family RRM_1 PF00076.22 OWF34645.1 - 8.4e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF34645.1 - 0.019 14.6 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OWF34645.1 - 0.093 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 MOSP_N PF02707.16 OWF34646.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein N-terminal region AAA_7 PF12775.7 OWF34647.1 - 0.046 13.2 0.1 0.5 9.9 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TACI-CRD2 PF09305.10 OWF34647.1 - 0.18 11.8 5.3 5.7 7.0 0.2 2.5 2 0 0 2 2 2 0 TACI, cysteine-rich domain Imm58 PF15581.6 OWF34648.1 - 0.27 11.3 2.4 26 5.0 0.1 3.2 3 0 0 3 3 3 0 Immunity protein 58 DUF1772 PF08592.11 OWF34648.1 - 6 7.2 12.9 81 3.5 6.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) TTL PF03133.15 OWF34649.1 - 1.2e-74 251.1 4.8 3e-74 249.8 4.4 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF34649.1 - 4.7e-05 22.8 0.4 0.01 15.1 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp NOA36 PF06524.12 OWF34649.1 - 0.002 17.5 5.9 0.002 17.5 5.9 1.8 2 0 0 2 2 2 1 NOA36 protein ATPgrasp_ST PF14397.6 OWF34649.1 - 0.029 13.6 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp zf-C2H2 PF00096.26 OWF34650.1 - 1.1e-46 154.8 116.4 3e-05 24.2 0.8 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF34650.1 - 2.2e-42 141.6 92.3 1.1e-07 31.9 0.0 14.6 14 1 0 14 14 14 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF34650.1 - 1.5e-40 134.3 106.8 0.0011 19.6 2.2 13.5 13 0 0 13 13 13 13 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF34650.1 - 5.2e-20 71.2 77.5 0.005 17.1 0.2 13.3 13 0 0 13 13 13 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF34650.1 - 2.5e-15 56.3 87.5 0.00057 20.2 0.7 12.9 13 0 0 13 13 12 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF34650.1 - 0.00035 20.5 87.3 0.038 14.0 0.3 12.4 13 0 0 13 13 13 5 C2H2-type zinc finger zf-Di19 PF05605.12 OWF34650.1 - 0.00068 19.9 5.5 0.00068 19.9 5.5 9.0 4 3 2 9 9 9 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 OWF34650.1 - 0.00077 20.1 50.6 0.16 12.7 4.2 7.6 4 2 4 8 8 8 5 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OWF34650.1 - 0.0049 17.2 8.9 0.0049 17.2 8.9 9.6 1 1 5 8 8 8 3 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OWF34650.1 - 0.0059 16.3 10.2 0.011 15.5 2.4 8.6 9 0 0 9 9 9 4 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 OWF34650.1 - 0.027 14.2 0.2 0.027 14.2 0.2 11.4 12 1 0 12 12 10 0 C2H2-type zinc-finger domain XPA_N PF01286.18 OWF34650.1 - 0.065 13.3 0.1 0.065 13.3 0.1 7.6 9 1 0 9 9 9 0 XPA protein N-terminal PyrI_C PF02748.15 OWF34650.1 - 0.13 12.1 0.2 0.13 12.1 0.2 8.0 9 3 3 12 12 10 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain BolA PF01722.18 OWF34650.1 - 1.5 9.1 7.4 6.3 7.2 0.1 4.8 3 2 1 4 4 4 0 BolA-like protein zinc_ribbon_15 PF17032.5 OWF34650.1 - 4.5 8.1 53.8 2.3 9.1 2.5 7.6 5 3 3 8 8 7 0 zinc-ribbon family NNMT_PNMT_TEMT PF01234.17 OWF34651.1 - 1e-52 178.9 0.0 1.1e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 OWF34651.1 - 2.5e-05 24.2 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF34651.1 - 3.8e-05 24.3 0.0 0.27 12.0 0.0 2.7 2 1 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 OWF34651.1 - 0.0049 16.7 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain N2227 PF07942.12 OWF34651.1 - 0.0065 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 OWF34651.1 - 0.0066 17.2 0.0 0.031 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF34651.1 - 0.021 15.5 0.0 0.41 11.3 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OWF34651.1 - 0.15 11.4 0.0 4.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) HAUS5 PF14817.6 OWF34653.1 - 1.9e-100 337.6 38.2 2.2e-100 337.4 38.2 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 FRP PF18032.1 OWF34653.1 - 0.013 16.1 5.0 0.58 10.8 0.5 3.7 3 0 0 3 3 3 0 Photoprotection regulator fluorescence recovery protein Mce4_CUP1 PF11887.8 OWF34653.1 - 0.1 12.1 0.4 3.4 7.0 0.3 2.8 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3800 PF12686.7 OWF34653.1 - 4.2 8.0 6.0 51 4.5 5.1 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Methyltransf_31 PF13847.6 OWF34654.1 - 9e-11 41.8 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF34654.1 - 2e-10 41.2 0.0 5.4e-10 39.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF34654.1 - 6e-09 36.5 0.0 2e-08 34.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF34654.1 - 1.4e-08 34.7 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF34654.1 - 3.2e-08 34.1 0.0 1.2e-07 32.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OWF34654.1 - 7e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OWF34654.1 - 0.0005 19.7 0.0 0.00099 18.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OWF34654.1 - 0.00059 19.8 0.1 0.0013 18.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF34654.1 - 0.0032 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 OWF34654.1 - 0.0037 16.9 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 OWF34654.1 - 0.012 14.2 0.0 0.021 13.4 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 OWF34654.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 OWF34654.1 - 0.031 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 OWF34654.1 - 0.043 13.1 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 OWF34654.1 - 0.048 13.5 0.0 0.62 9.9 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase DREV PF05219.12 OWF34654.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.13 OWF34654.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 OWF34654.1 - 0.17 10.9 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_9 PF08003.11 OWF34654.1 - 0.2 10.5 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) 7tm_1 PF00001.21 OWF34656.1 - 9.2e-21 74.3 2.7 2.7e-20 72.8 2.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gemini_AL3 PF01407.17 OWF34656.1 - 0.0022 17.8 0.2 0.0044 16.9 0.2 1.5 1 0 0 1 1 1 1 Geminivirus AL3 protein DAGK_acc PF00609.19 OWF34656.1 - 0.015 15.6 0.1 0.02 15.2 0.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain DUF2975 PF11188.8 OWF34656.1 - 2.2 8.2 8.2 0.14 12.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) SNF PF00209.18 OWF34657.1 - 2.3e-220 732.7 45.5 1.2e-219 730.4 45.5 1.8 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF34658.1 - 1.9e-19 69.8 0.6 2.2e-19 69.5 0.6 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family cNMP_binding PF00027.29 OWF34659.1 - 8.1e-18 64.3 0.1 6.6e-14 51.8 0.1 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Exostosin PF03016.15 OWF34660.1 - 8.2e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Exostosin family SnAC PF14619.6 OWF34660.1 - 0.03 14.9 0.0 0.063 13.9 0.0 1.4 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex P-mevalo_kinase PF04275.14 OWF34660.1 - 0.1 12.5 0.8 0.25 11.3 0.8 1.6 1 0 0 1 1 1 0 Phosphomevalonate kinase UPF0020 PF01170.18 OWF34661.1 - 1.4e-32 113.0 0.1 7.8e-32 110.6 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 OWF34661.1 - 4.2e-07 30.2 0.3 1.2e-06 28.7 0.0 2.0 2 1 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.6 OWF34661.1 - 4.8e-07 30.4 0.1 2.9e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF34661.1 - 3.1e-06 27.1 0.0 7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF34661.1 - 5.1e-05 22.7 0.4 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OWF34661.1 - 0.00015 22.3 0.4 0.0028 18.2 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain AviRa PF11599.8 OWF34661.1 - 0.00056 19.4 0.0 0.0038 16.7 0.0 2.1 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_18 PF12847.7 OWF34661.1 - 0.00068 19.6 0.0 0.002 18.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 OWF34661.1 - 0.0058 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 OWF34661.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain BHD_3 PF10405.9 OWF34662.1 - 2.4e-25 88.7 0.0 8.7e-25 86.9 0.0 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 OWF34662.1 - 1.4e-21 76.8 1.3 1.4e-21 76.8 1.3 5.8 3 2 2 5 5 5 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 OWF34662.1 - 1.8e-18 66.1 0.0 4.7e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OWF34662.1 - 1.4e-12 48.4 0.4 1.4e-12 48.4 0.4 6.9 4 3 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OWF34662.1 - 0.03 14.8 0.0 1.6 9.2 0.0 3.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily MNHE PF01899.16 OWF34663.1 - 0.064 13.0 0.1 0.068 12.9 0.1 1.1 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit WBP-1 PF11669.8 OWF34663.1 - 1.8 9.3 5.3 3.6 8.3 5.3 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 ACOX PF01756.19 OWF34664.1 - 1.4e-51 174.6 0.5 2.3e-50 170.6 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OWF34664.1 - 1.1e-28 100.3 0.3 3.4e-28 98.7 0.1 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OWF34664.1 - 3.2e-09 36.9 0.0 6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OWF34664.1 - 0.067 13.9 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OWF34664.1 - 0.097 12.9 2.8 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Laminin_G_3 PF13385.6 OWF34665.1 - 9.6e-06 25.8 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CBM_14 PF01607.24 OWF34665.1 - 0.16 12.1 3.8 0.12 12.5 0.7 2.3 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain VIT PF08487.10 OWF34666.1 - 6e-28 97.3 0.4 1.4e-27 96.1 0.4 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain ITI_HC_C PF06668.12 OWF34666.1 - 9e-18 64.6 2.0 9.7e-18 64.5 0.4 2.0 2 1 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VWA PF00092.28 OWF34666.1 - 1.8e-16 60.9 1.6 4.8e-16 59.5 0.4 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF34666.1 - 1.9e-14 53.9 0.0 3.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF34666.1 - 5.2e-10 39.9 0.1 1.4e-09 38.5 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 OWF34666.1 - 6.8e-05 23.1 0.1 0.00014 22.1 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2201 PF09967.9 OWF34666.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 VWA-like domain (DUF2201) ABC2_membrane_3 PF12698.7 OWF34667.1 - 3.1e-69 233.7 43.6 2.8e-46 158.2 18.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 OWF34667.1 - 8.4e-53 178.6 0.0 2.2e-26 93.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OWF34667.1 - 1.2e-23 84.4 0.1 1.4e-08 34.9 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF34667.1 - 7.3e-06 25.6 0.0 2.2 7.6 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OWF34667.1 - 4.7e-05 24.0 2.6 0.16 12.5 0.2 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 OWF34667.1 - 0.0022 17.3 0.0 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 OWF34667.1 - 0.0028 17.4 0.1 3.7 7.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 OWF34667.1 - 0.0067 16.1 1.8 0.49 10.0 0.3 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 OWF34667.1 - 0.011 15.4 2.8 0.52 10.1 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 OWF34667.1 - 0.012 15.9 0.0 5 7.4 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 OWF34667.1 - 0.021 14.6 2.0 0.25 11.1 0.4 2.6 2 0 0 2 2 2 0 MukB N-terminal RsgA_GTPase PF03193.16 OWF34667.1 - 0.024 14.5 0.6 0.93 9.4 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 OWF34667.1 - 0.026 14.2 0.0 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 OWF34667.1 - 0.06 13.0 1.3 1.6 8.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 OWF34667.1 - 0.096 13.4 0.0 16 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_22 PF13401.6 OWF34667.1 - 0.11 12.8 1.3 4.5 7.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 OWF34668.1 - 2.4e-71 240.6 40.8 2.9e-46 158.2 17.0 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 OWF34668.1 - 1.1e-53 181.4 0.1 2.4e-27 96.1 0.1 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OWF34668.1 - 2.2e-23 83.6 0.1 1.5e-08 34.9 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF34668.1 - 1.3e-05 24.7 0.0 4.3 6.7 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OWF34668.1 - 3.1e-05 24.6 2.0 0.16 12.5 0.3 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 OWF34668.1 - 0.0015 17.9 0.0 1 8.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 OWF34668.1 - 0.0047 17.1 0.0 2.4 8.5 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 OWF34668.1 - 0.0054 16.4 1.9 0.49 10.0 0.3 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OWF34668.1 - 0.0059 16.4 0.1 4 7.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OWF34668.1 - 0.0092 15.7 2.6 0.51 10.1 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OWF34668.1 - 0.016 15.0 0.0 1.2 8.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 OWF34668.1 - 0.019 14.7 0.4 0.83 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF34668.1 - 0.023 14.6 0.8 0.91 9.4 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase MukB PF04310.12 OWF34668.1 - 0.058 13.2 3.8 0.25 11.1 0.4 2.8 3 0 0 3 3 3 0 MukB N-terminal DUF4162 PF13732.6 OWF34668.1 - 0.07 13.9 0.0 12 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_22 PF13401.6 OWF34668.1 - 0.12 12.6 1.5 4.9 7.4 0.2 2.6 2 0 0 2 2 2 0 AAA domain DUF3533 PF12051.8 OWF34668.1 - 2.5 7.0 23.1 1.4 7.8 8.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) Death PF00531.22 OWF34669.1 - 6.9e-07 29.3 0.3 0.00017 21.7 0.1 2.3 2 0 0 2 2 2 2 Death domain CARD_2 PF16739.5 OWF34669.1 - 9.4e-06 25.5 0.1 4.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Caspase recruitment domain CARD PF00619.21 OWF34669.1 - 0.0016 18.4 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain SKI PF01202.22 OWF34670.1 - 9.1e-29 100.6 0.0 1.7e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Thr_synth_N PF14821.6 OWF34670.1 - 5.6e-17 61.7 0.0 1.7e-15 57.0 0.0 3.4 5 0 0 5 5 5 1 Threonine synthase N terminus PALP PF00291.25 OWF34670.1 - 4.3e-08 32.9 0.0 2.1e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_18 PF13238.6 OWF34670.1 - 1.1e-05 25.9 0.0 3.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF34670.1 - 0.0037 17.4 0.0 0.017 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OWF34670.1 - 0.0051 17.2 0.0 0.02 15.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OWF34670.1 - 0.038 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 OWF34670.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 OWF34670.1 - 0.066 13.2 1.0 1.4 8.9 0.3 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Acid_PPase PF12689.7 OWF34670.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase Zeta_toxin PF06414.12 OWF34670.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 OWF34670.1 - 0.16 12.4 0.3 12 6.3 0.0 3.3 4 0 0 4 4 4 0 AAA domain Laps PF10169.9 OWF34672.1 - 2.3e-22 79.9 15.1 4.9e-22 78.9 15.1 1.5 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 OWF34672.1 - 0.0016 18.6 5.1 0.0016 18.6 5.1 2.6 3 1 1 4 4 4 1 Protein of unknown function (DUF2423) Synaphin PF05835.12 OWF34672.1 - 0.065 13.5 10.9 0.031 14.5 8.9 1.5 1 1 0 1 1 1 0 Synaphin protein ATP-synt_E PF05680.12 OWF34672.1 - 2.6 8.4 8.0 0.43 11.0 3.7 1.8 1 1 1 2 2 2 0 ATP synthase E chain Actin PF00022.19 OWF34673.1 - 7.4e-34 117.0 0.0 1.7e-18 66.5 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 OWF34673.1 - 1.6e-09 37.4 0.7 0.00017 20.9 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family DUF4200 PF13863.6 OWF34674.1 - 7.7e-36 123.1 21.8 7.7e-36 123.1 21.8 5.4 5 1 1 6 6 6 1 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 OWF34674.1 - 4.2 7.4 10.5 14 5.7 6.2 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 OWF34674.1 - 5 7.7 8.8 18 5.9 2.4 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Amidohydro_3 PF07969.11 OWF34675.1 - 2.7e-21 76.6 0.3 3.5e-12 46.6 0.0 2.6 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 OWF34675.1 - 1.9e-17 63.6 0.7 5.7e-12 45.6 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family WBP-1 PF11669.8 OWF34676.1 - 9.9e-05 22.9 0.0 0.00031 21.3 0.0 2.0 1 0 0 1 1 1 1 WW domain-binding protein 1 Ldl_recept_a PF00057.18 OWF34676.1 - 0.0034 17.6 10.9 0.0034 17.6 10.9 2.2 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A MLANA PF14991.6 OWF34676.1 - 0.037 14.3 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A FAM163 PF15069.6 OWF34676.1 - 0.041 14.3 0.4 0.041 14.3 0.4 2.2 2 0 0 2 2 2 0 FAM163 family DUF1634 PF07843.11 OWF34676.1 - 0.056 13.5 0.4 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) SKG6 PF08693.10 OWF34676.1 - 0.082 12.3 1.5 0.24 10.8 1.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD45 PF12567.8 OWF34676.1 - 0.26 11.3 6.0 0.14 12.1 2.7 2.2 2 0 0 2 2 2 0 Leukocyte receptor CD45 EphA2_TM PF14575.6 OWF34676.1 - 0.27 12.2 2.6 0.32 11.9 0.1 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Conotoxin PF02950.17 OWF34678.1 - 0.53 11.3 0.0 0.53 11.3 0.0 3.6 2 2 2 4 4 4 0 Conotoxin MttA_Hcf106 PF02416.16 OWF34678.1 - 1.1 8.7 2.6 5 6.5 2.6 2.2 1 0 0 1 1 1 0 mttA/Hcf106 family STAT_bind PF02864.15 OWF34678.1 - 9.6 6.8 9.7 0.78 10.3 4.4 1.8 2 0 0 2 2 2 0 STAT protein, DNA binding domain TMEM154 PF15102.6 OWF34679.1 - 0.036 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.18 OWF34679.1 - 0.064 13.5 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A DUF2207 PF09972.9 OWF34679.1 - 0.069 11.9 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pox_A14 PF05767.12 OWF34680.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Collectrin PF16959.5 OWF34680.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Renal amino acid transporter FAM183 PF14886.6 OWF34682.1 - 0.0043 17.7 1.0 0.0097 16.6 1.0 1.9 1 1 0 1 1 1 1 FAM183A and FAM183B related DUF4541 PF15074.6 OWF34682.1 - 0.021 15.4 0.0 0.063 13.9 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4541) F-box-like PF12937.7 OWF34683.1 - 6.1e-15 54.8 0.1 2e-14 53.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF34683.1 - 1e-09 38.0 0.0 1.3e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 OWF34683.1 - 1.6e-09 37.8 3.6 0.0016 18.8 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF34683.1 - 7.6e-09 34.9 3.3 0.059 13.4 0.1 5.1 4 0 0 4 4 4 3 Leucine Rich repeat Hemerythrin PF01814.23 OWF34683.1 - 0.00019 22.1 0.0 0.00065 20.3 0.0 2.0 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain LRR_1 PF00560.33 OWF34683.1 - 0.00028 21.0 4.3 2.1 9.2 0.3 5.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 OWF34683.1 - 0.0052 16.5 0.7 3.8 7.3 0.0 3.7 4 1 0 4 4 4 1 Leucine rich repeat Csm1_B PF18211.1 OWF34683.1 - 0.14 12.0 0.4 0.4 10.5 0.4 1.8 1 0 0 1 1 1 0 Csm1 subunit domain B MnmE_helical PF12631.7 OWF34683.1 - 1.5 8.9 6.7 1.1 9.3 0.7 3.0 3 1 0 3 3 3 0 MnmE helical domain Pkinase PF00069.25 OWF34685.1 - 1.1e-57 195.4 0.0 1.4e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34685.1 - 2.1e-22 79.7 0.4 4.3e-22 78.6 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OWF34685.1 - 2.5e-06 27.6 0.3 0.00027 21.0 0.0 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OWF34685.1 - 0.0031 17.1 3.5 0.0051 16.4 3.5 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OWF34685.1 - 0.0088 15.7 3.4 0.0089 15.6 1.8 1.8 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 OWF34685.1 - 0.02 14.4 2.7 0.087 12.3 0.1 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 OWF34685.1 - 0.032 13.6 1.7 0.051 12.9 1.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-actin_cap_A PF01267.17 OWF34687.1 - 3e-78 262.9 0.5 3.8e-78 262.6 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF2135 PF09906.9 OWF34687.1 - 0.1 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) DUF3504 PF12012.8 OWF34689.1 - 2.7e-31 108.7 0.0 3.1e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Phage_integrase PF00589.22 OWF34689.1 - 0.00042 20.2 0.0 0.00069 19.4 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family DUF3435 PF11917.8 OWF34689.1 - 0.0053 15.7 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) SAP30_Sin3_bdg PF13867.6 OWF34692.1 - 1.8 9.0 4.5 2.3 8.6 0.0 2.7 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Sulfotransfer_2 PF03567.14 OWF34693.1 - 8.5e-44 150.4 7.2 1e-43 150.1 7.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF4355 PF14265.6 OWF34693.1 - 0.15 12.3 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) SWIRM PF04433.17 OWF34693.1 - 0.26 11.6 3.3 0.99 9.8 2.7 2.3 1 1 0 1 1 1 0 SWIRM domain Sulfotransfer_2 PF03567.14 OWF34694.1 - 2.7e-22 79.9 0.6 3.5e-22 79.5 0.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family OppC_N PF12911.7 OWF34694.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Sulfotransfer_2 PF03567.14 OWF34695.1 - 5.7e-45 154.2 3.9 8.2e-45 153.7 3.9 1.2 1 0 0 1 1 1 1 Sulfotransferase family rve_2 PF13333.6 OWF34695.1 - 0.14 12.4 2.9 6.9 6.9 0.2 2.6 2 0 0 2 2 2 0 Integrase core domain DUF3504 PF12012.8 OWF34696.1 - 8.8e-19 68.0 0.2 1e-18 67.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Peptidase_M1_N PF17900.1 OWF34697.1 - 2e-05 24.8 19.6 1.4 9.1 0.7 6.3 1 1 6 7 7 7 7 Peptidase M1 N-terminal domain DUF5514 PF17633.2 OWF34697.1 - 0.0043 17.3 25.7 12 6.1 0.2 7.9 1 1 7 8 8 8 2 Family of unknown function (DUF5514) AntA PF08346.12 OWF34697.1 - 0.14 12.8 9.7 9.8 6.8 0.0 6.5 5 2 1 6 6 6 0 AntA/AntB antirepressor DUF3394 PF11874.8 OWF34697.1 - 0.23 11.1 1.8 1.3e+02 2.2 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF3394) PARG_cat PF05028.14 OWF34697.1 - 0.74 9.0 11.1 7.5 5.7 0.2 5.0 1 1 4 6 6 6 0 Poly (ADP-ribose) glycohydrolase (PARG) CagY_M PF07337.11 OWF34697.1 - 0.93 9.2 2.8 13 5.5 0.8 4.2 2 0 0 2 2 2 0 DC-EC Repeat Pih1_fungal_CS PF18482.1 OWF34697.1 - 1.3 9.6 24.8 12 6.5 0.4 6.9 1 1 4 6 6 6 0 Fungal Pih1 CS domain Pkinase PF00069.25 OWF34698.1 - 5.5e-64 216.1 0.0 6.9e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34698.1 - 7.4e-27 94.3 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF34698.1 - 4.6e-11 42.6 0.0 1.1e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OWF34698.1 - 1.4e-08 34.3 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OWF34698.1 - 0.014 15.0 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OWF34698.1 - 0.015 14.9 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OWF34698.1 - 0.051 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OWF34698.1 - 0.076 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MSC PF09402.10 OWF34699.1 - 3e-18 66.4 8.1 3.6e-18 66.1 0.6 2.5 3 0 0 3 3 3 2 Man1-Src1p-C-terminal domain DUF2207 PF09972.9 OWF34699.1 - 0.00012 21.0 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RBM39linker PF15519.6 OWF34699.1 - 0.00027 21.9 4.0 0.00083 20.4 0.0 3.3 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RIFIN PF02009.16 OWF34699.1 - 0.036 14.0 7.6 3.2 7.6 3.8 2.9 2 1 0 3 3 3 0 Rifin LEM PF03020.15 OWF34699.1 - 0.064 12.8 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 LEM domain DUF1279 PF06916.13 OWF34699.1 - 0.2 12.2 0.3 0.79 10.3 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Transket_pyr PF02779.24 OWF34700.1 - 1e-46 158.8 0.0 1.5e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OWF34700.1 - 3e-39 133.7 0.0 8.1e-39 132.3 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Mito_carr PF00153.27 OWF34701.1 - 5.3e-47 157.7 6.6 9.2e-17 60.8 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein 7tm_2 PF00002.24 OWF34702.1 - 1.5e-42 145.6 21.1 2.1e-42 145.1 21.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 OWF34702.1 - 3.2e-13 50.0 1.5 1.1e-12 48.3 1.5 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Frizzled PF01534.17 OWF34702.1 - 0.00017 20.8 13.4 0.00032 19.9 13.4 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region PHO4 PF01384.20 OWF34702.1 - 0.07 12.2 0.5 0.12 11.4 0.5 1.3 1 0 0 1 1 1 0 Phosphate transporter family zf-C2H2_4 PF13894.6 OWF34703.1 - 5.6e-122 387.7 295.6 0.00042 20.9 1.1 43.1 44 0 0 44 44 44 38 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF34703.1 - 3.4e-121 389.4 312.4 3.7e-05 23.9 1.9 41.6 44 0 0 44 44 40 37 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF34703.1 - 9.6e-53 174.4 314.1 0.0011 19.3 0.2 44.4 42 3 0 42 42 41 26 Zinc-finger double domain zf-met PF12874.7 OWF34703.1 - 7.5e-35 118.3 210.0 0.0039 17.5 0.1 40.2 41 0 0 41 41 41 19 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF34703.1 - 6.6e-30 102.5 284.4 0.00041 20.3 1.8 39.5 44 1 0 44 44 41 23 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF34703.1 - 5.9e-24 83.8 227.0 0.00013 22.2 0.4 35.3 40 0 0 40 40 36 16 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OWF34703.1 - 9.6e-08 32.2 162.3 0.031 14.6 0.8 17.7 11 5 7 19 19 19 8 C2H2-type zinc ribbon Elf4 PF07011.11 OWF34703.1 - 4.9e-05 23.2 0.1 1.1 9.2 0.0 3.5 3 0 0 3 3 3 2 Early Flowering 4 domain zf-H2C2_5 PF13909.6 OWF34703.1 - 7.4e-05 22.4 21.4 0.001 18.8 0.8 21.1 25 0 0 25 25 23 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 OWF34703.1 - 0.0072 16.1 5.2 0.0072 16.1 5.2 27.4 31 0 0 31 31 29 7 zinc-finger C2H2-type RhoGEF67_u1 PF16615.5 OWF34703.1 - 0.084 13.4 5.9 87 3.7 0.2 5.3 5 0 0 5 5 5 0 Unstructured region one on RhoGEF 6 and 7 DUF5316 PF17247.2 OWF34703.1 - 0.096 12.7 0.0 67 3.6 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5316) TDH PF03347.13 OWF34703.1 - 0.14 11.7 0.0 26 4.3 0.0 3.7 4 0 0 4 4 4 0 Vibrio thermostable direct hemolysin zf-C2HC_2 PF13913.6 OWF34703.1 - 1.1 9.3 0.0 0.62 10.0 0.0 31.8 38 1 1 39 39 36 0 zinc-finger of a C2HC-type DNA_pol_D_N PF18018.1 OWF34703.1 - 1.4 9.1 5.9 26 4.9 0.1 3.5 3 0 0 3 3 3 0 DNA polymerase delta subunit OB-fold domain Amidase PF01425.21 OWF34704.1 - 8.2e-98 328.3 0.0 1e-97 327.9 0.0 1.0 1 0 0 1 1 1 1 Amidase AbiEii PF08843.11 OWF34704.1 - 0.15 11.9 0.0 0.36 10.8 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system TEX13 PF15186.6 OWF34705.1 - 0.02 14.6 13.0 0.02 14.6 13.0 2.8 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family Stimulus_sens_1 PF13756.6 OWF34705.1 - 0.43 11.2 5.6 0.26 11.9 2.3 2.1 1 1 1 2 2 2 0 Stimulus-sensing domain V_ATPase_I PF01496.19 OWF34705.1 - 1.4 6.7 24.6 1.7 6.4 24.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLZ PF16526.5 OWF34705.1 - 3.8 7.9 28.6 0.1 13.0 4.3 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Anti-adapt_IraP PF10796.9 OWF34705.1 - 6.3 7.4 16.7 0.18 12.4 8.3 2.4 2 1 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein FUSC PF04632.12 OWF34705.1 - 8.8 4.7 4.9 9.9 4.6 4.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mito_carr PF00153.27 OWF34706.1 - 1.1e-66 220.8 1.2 6.7e-23 80.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF34706.1 - 0.0032 16.7 1.4 5.5 6.1 0.1 3.4 2 1 2 4 4 4 2 Gammaproteobacterial serine protease Cadherin PF00028.17 OWF34707.1 - 9.6e-160 519.6 33.4 9.2e-22 77.3 0.2 10.3 10 0 0 10 10 10 9 Cadherin domain Laminin_G_2 PF02210.24 OWF34707.1 - 1.5e-44 151.6 5.0 1.8e-26 93.2 0.1 3.9 4 0 0 4 4 3 2 Laminin G domain 7tm_2 PF00002.24 OWF34707.1 - 5.2e-36 124.2 19.3 7.9e-36 123.6 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_1 PF00054.23 OWF34707.1 - 1.1e-31 109.8 0.4 3.4e-20 72.6 0.0 3.5 4 0 0 4 4 3 2 Laminin G domain GAIN PF16489.5 OWF34707.1 - 7e-31 107.3 0.6 1.7e-30 106.1 0.6 1.7 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.21 OWF34707.1 - 1.3e-11 44.8 0.4 6.2e-11 42.6 0.4 2.4 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Cadherin_2 PF08266.12 OWF34707.1 - 4.7e-10 39.2 0.2 0.59 10.0 0.0 8.0 8 0 0 8 8 8 1 Cadherin-like EGF PF00008.27 OWF34707.1 - 1.4e-08 34.9 39.1 4.1e-06 27.0 10.7 8.0 9 0 0 9 9 5 4 EGF-like domain Laminin_EGF PF00053.24 OWF34707.1 - 3.9e-07 30.1 12.6 3.9e-07 30.1 12.6 7.7 5 2 2 7 7 5 2 Laminin EGF domain Cadherin_3 PF16184.5 OWF34707.1 - 1.5e-06 28.2 27.4 2 8.5 0.1 9.0 9 0 0 9 9 9 3 Cadherin-like RET_CLD1 PF17756.1 OWF34707.1 - 5e-05 23.6 0.4 16 5.8 0.0 6.3 7 0 0 7 7 7 0 RET Cadherin like domain 1 SusE PF14292.6 OWF34707.1 - 0.61 10.3 9.0 1.2 9.5 0.0 4.8 5 0 0 5 5 4 0 SusE outer membrane protein SR-25 PF10500.9 OWF34707.1 - 4.9 6.7 14.6 6.3 6.3 13.4 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_M16 PF00675.20 OWF34708.1 - 4.9e-53 179.1 0.2 9.7e-53 178.2 0.1 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OWF34708.1 - 9.6e-39 133.3 0.0 8.4e-38 130.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Lactamase_B_2 PF12706.7 OWF34709.1 - 1.9e-38 132.0 0.0 2.9e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OWF34709.1 - 5.6e-09 36.1 0.0 1.6e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF34709.1 - 0.26 11.3 4.8 0.98 9.4 3.2 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OWF34710.1 - 1.4e-35 122.7 0.1 2e-35 122.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OWF34710.1 - 3.8e-12 46.4 0.2 8.1e-12 45.3 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF34710.1 - 0.44 10.5 4.1 3.3 7.6 3.7 2.3 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OWF34711.1 - 2.6e-38 131.6 0.0 8.2e-38 129.9 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OWF34711.1 - 9.5e-13 48.4 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF34711.1 - 0.00023 21.3 0.5 0.0005 20.1 0.5 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3091 PF11291.8 OWF34711.1 - 0.0037 17.4 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3091) Ras PF00071.22 OWF34712.1 - 1.3e-56 190.7 0.0 1.5e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF34712.1 - 6e-23 81.3 0.0 8.5e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF34712.1 - 1.4e-09 37.6 0.0 2.6e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF34712.1 - 0.0019 17.8 0.0 0.0035 16.9 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OWF34712.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF34712.1 - 0.042 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Mon2_C PF16206.5 OWF34713.1 - 6.8e-283 940.6 1.2 1.5e-282 939.4 1.2 1.5 1 1 0 1 1 1 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 OWF34713.1 - 5.6e-18 64.6 0.2 3.4e-17 62.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DUF1770 PF08589.10 OWF34714.1 - 0.011 16.7 12.0 1.6e+02 3.3 0.1 7.6 1 1 8 9 9 9 0 Fungal protein of unknown function (DUF1770) Pentapeptide_4 PF13599.6 OWF34714.1 - 0.027 14.6 31.1 0.83 9.9 10.8 3.3 1 1 2 3 3 3 0 Pentapeptide repeats (9 copies) EHD_N PF16880.5 OWF34714.1 - 0.96 9.4 14.6 61 3.6 0.1 8.6 10 1 1 11 11 11 0 N-terminal EH-domain containing protein zf-primase PF09329.11 OWF34714.1 - 2.9 7.8 33.9 40 4.1 0.5 9.4 1 1 11 13 13 13 0 Primase zinc finger ELK PF03789.13 OWF34714.1 - 7.8 6.7 39.7 1.3e+02 2.8 0.1 11.8 13 0 0 13 13 13 0 ELK domain 7TM_GPCR_Srw PF10324.9 OWF34716.1 - 1.6e-38 132.8 32.9 2.1e-38 132.4 32.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF34716.1 - 1e-14 54.5 25.0 1.6e-14 53.9 25.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF34716.1 - 0.00012 21.8 33.4 0.00012 21.8 33.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF34716.1 - 0.056 12.8 31.0 0.11 11.9 31.0 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Abhydrolase_9_N PF15420.6 OWF34716.1 - 0.19 11.7 2.1 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Spore_YhaL PF14147.6 OWF34716.1 - 0.31 10.8 3.1 7.6 6.3 0.0 2.9 2 0 0 2 2 2 0 Sporulation protein YhaL LRR19-TM PF15176.6 OWF34716.1 - 2.4 8.2 9.8 3.1 7.9 0.1 3.3 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DCB PF16213.5 OWF34717.1 - 1.5e-65 220.2 11.9 3.3e-65 219.1 9.2 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 OWF34717.1 - 3.6e-52 176.4 0.5 3.6e-52 176.4 0.5 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cep3 PF16846.5 OWF34717.1 - 0.015 13.8 1.0 0.034 12.6 1.0 1.5 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B IBR PF01485.21 OWF34718.1 - 5.3e-13 49.0 32.9 7.4e-10 38.9 9.2 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OWF34718.1 - 0.00042 20.1 4.4 0.00042 20.1 4.4 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF34718.1 - 0.0012 18.7 7.9 0.0012 18.7 7.9 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF34718.1 - 0.0015 18.3 4.6 0.0015 18.3 4.6 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF34718.1 - 0.002 18.1 5.2 0.002 18.1 5.2 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF34718.1 - 0.002 18.4 8.9 0.002 18.4 8.9 4.6 4 0 0 4 4 4 1 Ring finger domain IBR PF01485.21 OWF34719.1 - 5.3e-10 39.4 9.2 5.3e-10 39.4 9.2 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OWF34719.1 - 0.0003 20.6 4.4 0.0003 20.6 4.4 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF34719.1 - 0.00089 19.2 7.9 0.00089 19.2 7.9 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF34719.1 - 0.0011 18.8 4.6 0.0011 18.8 4.6 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF34719.1 - 0.0015 18.5 5.2 0.0015 18.5 5.2 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF34719.1 - 0.0015 18.8 8.9 0.0015 18.8 8.9 4.5 4 0 0 4 4 4 1 Ring finger domain IBR PF01485.21 OWF34720.1 - 4.9e-13 49.1 32.9 7.3e-10 38.9 9.2 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OWF34720.1 - 0.00041 20.2 4.4 0.00041 20.2 4.4 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF34720.1 - 0.0012 18.8 7.9 0.0012 18.8 7.9 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF34720.1 - 0.0015 18.4 4.6 0.0015 18.4 4.6 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF34720.1 - 0.002 18.1 5.2 0.002 18.1 5.2 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF34720.1 - 0.002 18.4 8.9 0.002 18.4 8.9 4.6 4 0 0 4 4 4 1 Ring finger domain IBR PF01485.21 OWF34721.1 - 6.6e-15 55.1 21.2 4.6e-12 46.0 6.5 4.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OWF34721.1 - 0.00029 20.7 9.6 0.00029 20.7 9.6 4.2 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF34721.1 - 0.0005 20.0 7.5 0.0005 20.0 7.5 4.2 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF34721.1 - 0.00095 19.5 8.3 0.00095 19.5 8.3 4.4 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 OWF34721.1 - 0.0012 18.6 4.8 0.0012 18.6 4.8 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF34721.1 - 0.011 15.5 4.7 0.059 13.1 4.7 2.4 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_2 PF14445.6 OWF34721.1 - 0.012 15.8 3.1 0.012 15.8 3.1 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 zf-C3HC4 PF00097.25 OWF34721.1 - 1.5 8.7 32.4 0.044 13.6 7.0 4.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF34721.1 - 7.2 6.9 36.8 2.2 8.5 2.9 4.5 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING RPE65 PF03055.15 OWF34722.1 - 5.6e-63 213.7 0.6 6.1e-63 213.6 0.6 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 OWF34723.1 - 4.5e-83 280.0 0.9 5.1e-83 279.8 0.9 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 OWF34724.1 - 4.5e-83 280.0 0.9 5.1e-83 279.8 0.9 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein UNC-93 PF05978.16 OWF34726.1 - 0.00013 21.8 5.0 0.00013 21.8 5.0 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Ank_4 PF13637.6 OWF34727.1 - 8.1e-16 58.2 1.0 2.6e-08 34.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF34727.1 - 4.5e-15 55.5 2.9 4.6e-09 36.4 0.2 2.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF34727.1 - 3.3e-14 53.2 0.1 6e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF34727.1 - 2.5e-13 48.9 0.6 1.6e-05 24.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OWF34727.1 - 9.3e-12 44.8 0.3 0.00018 21.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ubiquitin_2 PF14560.6 OWF34727.1 - 0.0007 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF4207 PF13904.6 OWF34727.1 - 0.0014 18.4 18.7 0.0042 16.8 18.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4207) ubiquitin PF00240.23 OWF34727.1 - 0.0042 16.8 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF1506 PF07405.11 OWF34727.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) CPSF100_C PF13299.6 OWF34727.1 - 0.14 12.3 2.3 3.2 7.9 2.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal 2Fe-2S_thioredx PF01257.19 OWF34728.1 - 1.7e-58 196.6 0.0 2.1e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Tom37 PF10568.9 OWF34729.1 - 4.2e-23 82.0 0.0 8.9e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 OWF34729.1 - 8.4e-23 81.0 0.0 1.8e-22 79.9 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF34729.1 - 7.5e-22 76.9 0.0 1.8e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF34729.1 - 1.9e-05 24.6 0.0 4.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N_2 PF13602.6 OWF34730.1 - 3e-17 63.9 0.0 6.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF34730.1 - 1.7e-11 44.0 0.0 3.7e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OWF34730.1 - 1.5e-09 37.9 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Phage_TAC_14 PF16462.5 OWF34730.1 - 0.061 13.6 0.1 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Abhydrolase_8 PF06259.12 OWF34730.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase dsDNA_bind PF01984.20 OWF34730.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Double-stranded DNA-binding domain PRMT5_TIM PF17285.2 OWF34731.1 - 1.1e-75 254.2 0.0 1.5e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 OWF34731.1 - 8.3e-72 240.6 0.0 1.2e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OWF34731.1 - 1.5e-54 184.5 0.9 3e-54 183.6 0.9 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 OWF34731.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Sel_put PF04328.13 OWF34731.1 - 0.7 10.0 2.4 0.76 9.8 0.8 2.0 2 0 0 2 2 2 0 Selenoprotein, putative UPF0489 PF12640.7 OWF34732.1 - 4.6e-48 163.8 0.6 2.6e-47 161.3 0.6 2.0 1 1 0 1 1 1 1 UPF0489 domain PUF PF00806.19 OWF34733.1 - 2.5e-13 48.9 2.5 0.41 10.5 0.1 7.9 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat Arrestin_N PF00339.29 OWF34734.1 - 6.2e-35 120.4 0.0 4e-34 117.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF34734.1 - 4.2e-14 53.2 0.1 5e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF4638 PF15472.6 OWF34735.1 - 2e-05 24.5 1.4 2e-05 24.5 1.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4638) LAMTOR PF15454.6 OWF34735.1 - 0.7 10.5 6.9 2.4 8.9 3.4 2.8 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator zf-C2H2 PF00096.26 OWF34736.1 - 2e-24 84.6 34.5 2.6e-06 27.6 1.1 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF34736.1 - 6.8e-19 67.4 35.0 1.9e-07 31.2 0.3 5.6 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF34736.1 - 1.4e-18 66.0 35.7 0.00011 22.7 0.8 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF34736.1 - 3.5e-12 46.3 16.8 0.013 15.8 0.0 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF34736.1 - 2.8e-09 36.7 31.0 0.0044 17.0 1.0 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 OWF34736.1 - 3.5e-08 33.6 19.8 0.086 13.3 0.2 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OWF34736.1 - 0.019 14.9 17.6 3 7.9 0.8 5.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 OWF34736.1 - 0.032 15.0 0.7 0.032 15.0 0.7 3.0 2 1 0 2 2 1 0 zinc-ribbon family zf-BED PF02892.15 OWF34736.1 - 0.043 13.8 0.2 0.043 13.8 0.2 5.2 2 2 3 5 5 5 0 BED zinc finger PyrI_C PF02748.15 OWF34736.1 - 0.064 13.2 21.9 0.64 10.0 4.7 5.2 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 OWF34736.1 - 0.086 13.3 27.6 0.092 13.2 0.3 4.9 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_7 PF02591.15 OWF34736.1 - 0.12 12.6 2.8 1.1 9.5 0.3 3.3 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-AN1 PF01428.16 OWF34736.1 - 0.34 11.1 25.9 7.5 6.8 0.1 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 OWF34736.1 - 0.85 10.0 20.5 0.74 10.2 1.5 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 OWF34736.1 - 1.3 9.2 24.7 0.54 10.4 3.2 4.5 3 2 2 5 5 4 0 Zinc ribbon domain zf_UBZ PF18439.1 OWF34736.1 - 1.4 8.6 16.7 1.2 8.8 0.1 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 OWF34736.1 - 3 7.7 24.9 0.32 10.8 0.2 4.8 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_ZIC PF18366.1 OWF34736.1 - 5 7.3 12.3 7.6 6.7 0.6 4.6 2 1 3 5 5 5 0 Zic proteins zinc finger domain DUF4764 PF15961.5 OWF34736.1 - 5.3 5.6 13.2 3 6.4 0.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4764) Sprouty PF05210.13 OWF34736.1 - 8.8 6.8 21.0 0.28 11.6 3.6 2.7 2 1 0 2 2 2 0 Sprouty protein (Spry) ADK_lid PF05191.14 OWF34736.1 - 9.1 6.4 17.1 8.4 6.5 1.7 4.0 2 1 1 3 3 3 0 Adenylate kinase, active site lid tRNA-synt_1 PF00133.22 OWF34737.1 - 9.4e-50 169.5 0.1 1.9e-19 69.4 0.4 6.0 2 2 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OWF34737.1 - 4.2e-31 108.1 0.0 4.3e-22 78.4 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OWF34737.1 - 4.1e-15 55.8 0.0 2.8e-07 30.3 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.13 OWF34737.1 - 7.2e-05 22.8 0.1 0.00014 21.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OWF34737.1 - 0.0064 15.9 0.1 2 7.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 OWF34737.1 - 0.026 13.9 2.8 3.5 7.2 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain tRNA-synt_1f PF01921.18 OWF34737.1 - 0.029 13.3 0.0 5.9 5.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) TF_Zn_Ribbon PF08271.12 OWF34737.1 - 0.41 10.2 3.4 1.9 8.1 0.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 OWF34737.1 - 1.8 8.7 6.8 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zf-TFIIB PF13453.6 OWF34737.1 - 4.5 6.7 5.7 16 4.9 0.4 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger ARL2_Bind_BART PF11527.8 OWF34738.1 - 1.3e-29 102.7 13.2 1.6e-29 102.4 13.2 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART UNC-93 PF05978.16 OWF34739.1 - 2.7e-11 43.4 12.8 2.7e-11 43.4 12.8 3.3 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 Nic96 PF04097.14 OWF34740.1 - 9e-180 599.2 0.4 5.2e-179 596.7 0.4 1.9 1 1 0 1 1 1 1 Nup93/Nic96 Dus PF01207.17 OWF34741.1 - 3.8e-49 167.5 0.2 2.1e-48 165.0 0.2 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 OWF34741.1 - 6.1e-05 23.7 0.1 0.00019 22.1 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Pkinase PF00069.25 OWF34742.1 - 3.5e-27 95.4 0.0 4.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34742.1 - 9.3e-15 54.6 0.0 1.1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF34742.1 - 1.7e-10 40.2 0.0 1.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OWF34742.1 - 0.039 12.9 0.1 0.065 12.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EF-hand_1 PF00036.32 OWF34743.1 - 9.3e-17 59.3 3.3 0.00035 19.9 0.9 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF34743.1 - 1.6e-14 52.5 4.0 0.0022 17.8 0.3 4.5 4 0 0 4 4 4 3 EF-hand domain Acyltransferase PF01553.21 OWF34743.1 - 2.1e-14 53.3 0.0 4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_7 PF13499.6 OWF34743.1 - 4.4e-14 52.7 6.2 4.7e-09 36.6 4.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF34743.1 - 7e-12 45.0 3.0 7.2e-09 35.4 1.7 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF34743.1 - 3.7e-07 29.3 3.7 0.18 11.4 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 OWF34743.1 - 0.00011 22.1 2.6 0.025 14.5 0.0 2.7 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF34743.1 - 0.0051 17.1 0.2 0.012 15.9 0.2 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 OWF34743.1 - 0.01 16.0 0.1 0.033 14.4 0.1 1.8 2 0 0 2 2 2 0 p25-alpha Form-deh_trans PF09163.11 OWF34743.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane HMG_box PF00505.19 OWF34744.1 - 2.9e-07 30.8 0.7 1.1e-06 29.0 0.7 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF34744.1 - 0.041 14.5 0.5 0.041 14.5 0.5 2.3 2 0 0 2 2 2 0 HMG-box domain CUB PF00431.20 OWF34746.1 - 1.8e-21 76.5 0.9 1.5e-10 41.4 0.0 3.8 3 0 0 3 3 3 3 CUB domain EGF PF00008.27 OWF34746.1 - 0.0077 16.5 35.9 0.013 15.8 5.6 4.7 4 0 0 4 4 4 3 EGF-like domain ZapB PF06005.12 OWF34747.1 - 0.056 13.9 2.6 0.36 11.3 0.1 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Neur_chan_memb PF02932.16 OWF34747.1 - 3 7.8 10.5 0.27 11.3 3.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.32 OWF34748.1 - 3.9e-28 94.9 7.5 5e-07 28.8 0.0 5.4 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 OWF34748.1 - 1.7e-26 89.8 3.7 3.6e-06 26.5 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 OWF34748.1 - 3.4e-26 91.5 2.6 7.2e-10 39.2 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 OWF34748.1 - 5.9e-22 77.3 2.8 1.1e-08 34.8 0.0 4.5 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 OWF34748.1 - 5e-19 66.9 2.9 0.00014 21.2 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF34748.1 - 0.0088 16.4 0.1 2.4 8.5 0.0 3.0 3 2 0 3 3 3 1 EF-hand domain EF-hand_2 PF09068.11 OWF34748.1 - 0.013 15.6 0.0 5.7 7.1 0.0 3.3 3 1 0 3 3 3 0 EF hand EF-hand_10 PF14788.6 OWF34748.1 - 0.026 14.4 0.3 12 5.8 0.0 3.1 4 0 0 4 4 4 0 EF hand WWE PF02825.20 OWF34748.1 - 0.058 14.0 0.0 0.82 10.3 0.0 2.4 2 0 0 2 2 2 0 WWE domain SPARC_Ca_bdg PF10591.9 OWF34748.1 - 0.11 12.8 1.4 2.8 8.3 0.2 2.8 1 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Alpha_adaptin_C PF02296.16 OWF34748.1 - 0.11 12.6 0.1 0.87 9.8 0.0 2.1 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain DAGK_cat PF00781.24 OWF34749.1 - 5.4e-24 84.2 0.0 8.4e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PFK PF00365.20 OWF34749.1 - 0.079 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase DAGK_cat PF00781.24 OWF34750.1 - 1.2e-24 86.3 0.0 2e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PFK PF00365.20 OWF34750.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase HisKA_7TM PF16927.5 OWF34750.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase DAGK_cat PF00781.24 OWF34751.1 - 1.1e-27 96.2 0.0 2.4e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PFK PF00365.20 OWF34751.1 - 0.068 12.5 0.1 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphofructokinase Glyco_transf_11 PF01531.16 OWF34752.1 - 3.5e-45 154.5 0.1 4.9e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 DUF4665 PF15679.5 OWF34753.1 - 8.6e-12 45.5 10.6 8.6e-12 45.5 10.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4665) Phasin PF05597.11 OWF34753.1 - 0.042 13.8 5.5 0.048 13.7 5.1 1.3 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF884 PF05959.11 OWF34753.1 - 0.051 13.2 0.2 0.053 13.1 0.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) MMPL PF03176.15 OWF34753.1 - 0.22 10.4 2.0 0.23 10.3 2.0 1.0 1 0 0 1 1 1 0 MMPL family Beta-lactamase PF00144.24 OWF34754.1 - 3.6e-33 115.2 0.0 5.3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase BTRD1 PF17660.1 OWF34754.1 - 0.00019 21.2 0.6 1.4 8.8 0.1 4.5 5 0 0 5 5 5 2 Bacterial tandem repeat domain 1 Beta-lactamase2 PF13354.6 OWF34754.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family zf-B_box PF00643.24 OWF34755.1 - 1e-06 28.8 10.5 1.8e-06 28.0 10.5 1.4 1 0 0 1 1 1 1 B-box zinc finger SGL PF08450.12 OWF34755.1 - 0.016 14.8 0.1 6.9 6.2 0.0 3.1 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region dUTPase_2 PF08761.11 OWF34755.1 - 0.054 13.7 1.3 0.14 12.4 1.3 1.7 1 1 0 1 1 1 0 dUTPase NHL PF01436.21 OWF34755.1 - 0.086 12.9 0.3 13 6.0 0.0 3.5 4 0 0 4 4 4 0 NHL repeat ATP-grasp_6 PF18419.1 OWF34755.1 - 0.09 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp-like domain zf-piccolo PF05715.13 OWF34755.1 - 0.11 12.6 4.4 0.29 11.3 4.4 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger DUF1664 PF07889.12 OWF34755.1 - 2.3 8.3 5.2 2 8.4 3.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Reg_prop PF07494.11 OWF34756.1 - 0.00089 19.2 0.1 2.1 8.9 0.0 4.4 4 0 0 4 4 4 1 Two component regulator propeller Phytase-like PF13449.6 OWF34756.1 - 0.053 13.5 0.0 4.8 7.0 0.0 2.2 1 1 1 2 2 2 0 Esterase-like activity of phytase PIP49_C PF12260.8 OWF34756.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 NHL PF01436.21 OWF34756.1 - 0.11 12.6 1.9 35 4.7 0.0 4.3 4 0 0 4 4 4 0 NHL repeat DUF3797 PF12677.7 OWF34756.1 - 0.12 12.2 0.1 0.43 10.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) HPS3_N PF14761.6 OWF34756.1 - 0.2 11.2 1.6 11 5.4 0.1 2.7 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 UQ_con PF00179.26 OWF34757.1 - 1.6e-40 138.0 0.0 2.6e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.7 OWF34757.1 - 4.4e-09 36.1 0.1 1.5e-08 34.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF34757.1 - 5.9e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OWF34757.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 F-box DUF2555 PF10742.9 OWF34758.1 - 0.072 12.9 0.3 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Ribonuc_L-PSP PF01042.21 OWF34758.1 - 0.15 12.1 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Endoribonuclease L-PSP EF-hand_1 PF00036.32 OWF34759.1 - 5.3e-33 110.1 15.4 3.3e-09 35.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF34759.1 - 6.4e-32 109.8 6.8 5.4e-16 58.8 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF34759.1 - 6.3e-28 94.3 8.3 1.7e-09 36.9 0.3 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF34759.1 - 2.7e-24 84.8 14.6 2.2e-11 43.4 1.6 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF34759.1 - 1.1e-21 75.3 10.0 6.3e-07 28.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 OWF34759.1 - 4e-12 46.0 3.6 3.3e-05 23.8 0.1 2.9 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF34759.1 - 1.2e-11 44.7 4.4 5.2e-05 23.5 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF34759.1 - 1.2e-06 28.8 1.0 0.06 13.7 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF34759.1 - 6.2e-06 26.3 1.7 0.017 15.3 0.0 3.1 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_11 PF08976.11 OWF34759.1 - 2.8e-05 24.9 0.0 0.0046 17.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain DUF2267 PF10025.9 OWF34759.1 - 0.01 16.1 0.0 0.75 10.1 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) UBA_6 PF18039.1 OWF34759.1 - 0.023 14.6 0.1 12 5.9 0.0 3.1 4 0 0 4 4 4 0 UBA-like domain ExbD PF02472.16 OWF34759.1 - 0.048 13.8 0.0 0.53 10.4 0.0 2.2 1 1 1 2 2 2 0 Biopolymer transport protein ExbD/TolR UPF0154 PF03672.13 OWF34759.1 - 0.067 13.2 0.0 4 7.5 0.0 2.6 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0154) DUF853 PF05872.12 OWF34759.1 - 0.086 11.4 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF5580 PF17743.1 OWF34759.1 - 0.089 11.3 0.0 0.22 10.0 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF3349 PF11829.8 OWF34759.1 - 0.16 12.7 0.0 2.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) VCBS PF13517.6 OWF34759.1 - 8.6 7.0 8.9 13 6.4 1.0 2.7 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Abhydrolase_9_N PF15420.6 OWF34760.1 - 0.0051 16.8 0.0 0.0069 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus SIT PF15330.6 OWF34760.1 - 0.025 15.0 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Glycophorin_A PF01102.18 OWF34760.1 - 0.035 14.3 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A DUF4083 PF13314.6 OWF34760.1 - 0.13 12.2 1.1 0.18 11.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) RCR PF12273.8 OWF34760.1 - 2.7 8.7 8.5 0.13 12.9 0.7 2.2 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red UPF0086 PF01868.16 OWF34763.1 - 1.6e-28 98.5 0.0 3e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 AP-5_subunit_s1 PF15001.6 OWF34763.1 - 0.045 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 adh_short PF00106.25 OWF34764.1 - 7.3e-49 165.9 0.1 1e-48 165.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF34764.1 - 3.7e-29 101.9 0.0 5.1e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF34764.1 - 4.2e-19 69.2 0.1 5.8e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OWF34764.1 - 0.00048 19.3 0.4 0.00075 18.7 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OWF34764.1 - 0.00078 19.4 1.1 0.0056 16.6 1.1 2.3 1 1 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 OWF34764.1 - 0.00099 19.0 0.4 0.0051 16.7 0.3 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OWF34764.1 - 0.0011 18.4 0.2 0.0017 17.7 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 OWF34764.1 - 0.0054 17.2 0.7 0.0092 16.4 0.7 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 3Beta_HSD PF01073.19 OWF34764.1 - 0.0061 15.6 0.2 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_2 PF07992.14 OWF34764.1 - 0.011 15.0 0.3 0.017 14.4 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 OWF34764.1 - 0.016 14.6 0.2 0.039 13.4 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OWF34764.1 - 0.069 12.7 0.4 0.12 11.9 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.20 OWF34764.1 - 0.079 13.0 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 OWF34764.1 - 0.13 11.4 0.3 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OWF34764.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase WD40 PF00400.32 OWF34765.1 - 2.7e-19 69.1 21.7 1.4e-05 25.7 0.5 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 OWF34765.1 - 1.4e-06 28.2 9.0 1.4e-06 28.2 9.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF34765.1 - 1.9e-06 27.6 9.3 1.9e-06 27.6 9.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PQQ_3 PF13570.6 OWF34765.1 - 7.3e-06 26.3 0.0 0.15 12.6 0.0 3.4 3 0 0 3 3 3 2 PQQ-like domain zf-C3HC4_4 PF15227.6 OWF34765.1 - 0.00019 21.5 7.4 0.00019 21.5 7.4 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF34765.1 - 0.00038 20.2 7.7 0.00038 20.2 7.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 OWF34765.1 - 0.0006 20.4 8.0 0.0006 20.4 8.0 2.3 2 0 0 2 2 1 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 OWF34765.1 - 0.0015 18.4 9.6 0.0015 18.4 9.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 OWF34765.1 - 0.003 17.6 16.7 0.01 15.8 1.1 3.7 2 1 1 3 3 3 1 Seven in absentia protein family zf-RING_5 PF14634.6 OWF34765.1 - 0.005 16.8 10.6 0.005 16.8 10.6 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 OWF34765.1 - 0.013 15.3 3.6 0.035 13.9 3.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.9 OWF34765.1 - 0.018 15.6 0.4 0.06 13.9 0.4 1.9 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DivIC PF04977.15 OWF34765.1 - 0.023 14.5 1.7 0.038 13.8 0.9 1.8 1 1 0 1 1 1 0 Septum formation initiator BBS2_Mid PF14783.6 OWF34765.1 - 0.033 14.2 0.0 15 5.7 0.0 3.5 4 0 0 4 4 3 0 Ciliary BBSome complex subunit 2, middle region CCDC106 PF15794.5 OWF34765.1 - 0.081 12.6 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GAS PF13851.6 OWF34765.1 - 0.15 11.4 1.1 0.26 10.6 1.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-RING_6 PF14835.6 OWF34765.1 - 0.26 11.2 3.7 0.85 9.5 3.7 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3450 PF11932.8 OWF34765.1 - 0.31 10.3 2.2 0.5 9.6 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-RING_2 PF13639.6 OWF34765.1 - 1.1 9.6 19.9 0.047 14.0 9.9 2.9 2 0 0 2 2 2 0 Ring finger domain ECH_1 PF00378.20 OWF34766.1 - 1.1e-35 123.2 0.0 2.9e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF34766.1 - 2.6e-16 60.1 0.0 2.6e-16 60.1 0.0 2.3 2 1 1 3 3 3 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 OWF34766.1 - 2.1e-12 46.7 1.1 7.1e-12 45.1 1.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 OWF34766.1 - 0.03 14.2 0.5 0.1 12.5 0.5 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain ECH_1 PF00378.20 OWF34767.1 - 1.8e-40 138.8 0.0 3.1e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 OWF34767.1 - 2.3e-27 95.0 0.5 5.1e-27 93.9 0.5 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.5 OWF34767.1 - 4.5e-20 72.4 0.0 7.1e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF659 PF04937.15 OWF34767.1 - 0.051 13.4 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) Actin PF00022.19 OWF34768.1 - 2e-102 342.9 0.0 1.1e-101 340.4 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OWF34768.1 - 0.00091 18.1 0.0 0.0037 16.1 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 OWF34768.1 - 0.0059 15.7 0.0 0.0087 15.1 0.0 1.1 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; SK_channel PF03530.14 OWF34769.1 - 8e-27 93.5 2.4 8e-27 93.5 2.4 1.9 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 OWF34769.1 - 6.4e-14 51.7 0.2 6.4e-14 51.7 0.2 2.5 2 1 0 2 2 2 1 Ion channel CaMBD PF02888.16 OWF34769.1 - 1e-10 41.7 2.6 2e-10 40.7 2.6 1.5 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans PF00520.31 OWF34769.1 - 0.0032 16.7 9.5 0.014 14.6 9.5 2.1 1 1 0 1 1 1 1 Ion transport protein DUF21 PF01595.20 OWF34769.1 - 0.065 12.9 0.4 0.065 12.9 0.4 2.3 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain SK_channel PF03530.14 OWF34770.1 - 3.5e-32 110.8 5.1 3.5e-32 110.8 5.1 2.1 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 OWF34770.1 - 3.1e-12 46.3 4.8 3.1e-12 46.3 4.8 2.9 2 1 2 4 4 4 1 Ion channel CaMBD PF02888.16 OWF34770.1 - 3.8e-06 27.0 0.3 9.2e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Lig_chan PF00060.26 OWF34770.1 - 0.005 16.7 0.5 0.005 16.7 0.5 2.2 2 0 0 2 2 2 1 Ligand-gated ion channel DHR10 PF18595.1 OWF34770.1 - 0.041 13.9 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 OWF34770.1 - 0.13 12.7 1.5 0.33 11.4 0.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 OWF34770.1 - 0.16 11.9 0.8 0.53 10.3 0.8 1.9 1 1 0 1 1 1 0 Prefoldin subunit SK_channel PF03530.14 OWF34771.1 - 3.9e-37 126.8 3.6 3.9e-37 126.8 3.6 2.4 3 0 0 3 3 3 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 OWF34771.1 - 3.4e-15 55.7 3.4 3.4e-15 55.7 3.4 2.9 2 1 0 2 2 2 1 Ion channel CaMBD PF02888.16 OWF34771.1 - 4.1e-09 36.5 0.9 1.6e-08 34.6 0.9 1.9 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans PF00520.31 OWF34771.1 - 3.2e-05 23.3 14.2 0.00018 20.9 14.2 1.9 1 1 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 OWF34771.1 - 0.00029 20.7 0.2 0.00029 20.7 0.2 1.9 2 1 0 2 2 2 1 Ligand-gated ion channel DUF872 PF05915.12 OWF34771.1 - 0.0011 19.1 3.6 0.0098 16.1 0.2 2.9 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) MpPF26 PF07666.11 OWF34771.1 - 2.2 8.4 15.8 3.1 7.9 1.0 3.8 3 1 1 4 4 4 0 M penetrans paralogue family 26 Nucleotid_trans PF03407.16 OWF34772.1 - 1.8e-06 28.1 0.4 3.5e-06 27.1 0.1 1.7 2 1 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Adaptin_N PF01602.20 OWF34773.1 - 4.2e-145 484.3 10.8 5.1e-145 484.0 10.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OWF34773.1 - 1.4e-30 105.9 2.1 3.4e-30 104.6 2.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OWF34773.1 - 1.2e-09 38.4 9.3 3.6e-07 30.4 0.7 3.3 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Kinetochor_Ybp2 PF08568.10 OWF34773.1 - 0.0065 15.0 1.6 0.016 13.8 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF5578 PF17741.1 OWF34773.1 - 0.13 11.7 2.1 0.28 10.6 0.2 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5578) DUF1731 PF08338.11 OWF34774.1 - 1.8e-12 46.9 0.0 3.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 OWF34774.1 - 9.4e-09 35.1 0.1 7.6e-08 32.1 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OWF34774.1 - 1.9e-05 24.6 0.1 0.058 13.3 0.2 2.8 2 1 1 3 3 3 2 KR domain GDP_Man_Dehyd PF16363.5 OWF34774.1 - 0.0013 18.2 0.0 0.0039 16.6 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OWF34774.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 OWF34774.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 OWF34774.1 - 0.042 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.17 OWF34774.1 - 0.045 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 OWF34774.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 OWF34774.1 - 0.14 12.6 0.1 0.3 11.5 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-RING_2 PF13639.6 OWF34775.1 - 1.9e-11 44.1 7.0 4.9e-11 42.8 7.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF34775.1 - 5.7e-08 32.5 6.9 1.1e-07 31.6 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF34775.1 - 1.3e-07 31.4 5.4 2.5e-07 30.5 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) G2BR PF18442.1 OWF34775.1 - 4.1e-07 29.5 3.1 8.8e-07 28.5 3.1 1.6 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) CUE PF02845.16 OWF34775.1 - 6.8e-07 28.9 0.1 1.6e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.6 OWF34775.1 - 2.7e-06 27.1 2.3 5e-06 26.3 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF34775.1 - 8.4e-06 25.4 4.8 2.1e-05 24.1 1.4 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OWF34775.1 - 1.3e-05 25.1 2.9 2.9e-05 24.0 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OWF34775.1 - 1.6e-05 25.1 10.9 2.7e-05 24.3 8.5 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OWF34775.1 - 4.2e-05 23.3 3.9 7.8e-05 22.5 3.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF34775.1 - 5.9e-05 22.9 3.5 0.00012 22.0 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF34775.1 - 0.00032 20.7 2.8 0.00094 19.2 2.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OWF34775.1 - 0.0035 16.9 3.8 0.0035 16.9 3.8 1.7 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type Endonuclease_7 PF02945.15 OWF34775.1 - 0.12 12.3 0.8 0.31 11.0 0.8 1.6 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C3HC4_4 PF15227.6 OWF34775.1 - 0.72 10.1 5.2 1.5 9.1 5.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OWF34775.1 - 1.5 9.0 5.4 3.8 7.7 5.3 1.7 1 1 0 1 1 1 0 RING-variant domain Mab-21 PF03281.14 OWF34776.1 - 2.3e-26 92.8 0.9 4.1e-26 92.0 0.9 1.4 1 0 0 1 1 1 1 Mab-21 protein Mannosyl_trans PF05007.13 OWF34777.1 - 3e-87 292.7 24.7 4.3e-87 292.3 24.7 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 OWF34777.1 - 1.6e-15 57.0 27.5 2.2e-15 56.6 27.5 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U XPG_I_2 PF12813.7 OWF34778.1 - 9.9e-14 51.4 0.0 2.8e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 OWF34778.1 - 2.8e-06 27.7 0.0 1.5e-05 25.4 0.0 2.3 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 OWF34778.1 - 0.0098 15.8 0.1 0.072 13.0 0.1 2.3 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DAD PF02109.16 OWF34780.1 - 2.1e-47 159.9 2.8 2.4e-47 159.8 2.8 1.0 1 0 0 1 1 1 1 DAD family zf-C2H2 PF00096.26 OWF34781.1 - 5e-23 80.2 138.5 0.00059 20.2 0.8 18.2 18 0 0 18 18 18 13 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF34781.1 - 7.5e-21 73.6 109.5 1e-05 25.2 0.4 15.4 15 0 0 15 15 15 10 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OWF34781.1 - 1.5e-19 69.4 124.4 9.1e-05 22.7 1.2 18.5 20 1 0 20 20 20 9 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF34781.1 - 2.2e-16 59.1 137.2 0.0043 17.8 0.6 17.5 18 0 0 18 18 18 14 C2H2-type zinc finger DUF2719 PF10891.8 OWF34781.1 - 0.74 9.8 20.1 0.18 11.7 1.3 6.1 4 3 1 5 5 5 0 Protein of unknown function (DUF2719) Vps36-NZF-N PF16988.5 OWF34781.1 - 0.75 9.2 18.7 6.4 6.3 1.0 6.3 5 0 0 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain HH_signal PF01085.18 OWF34782.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.11 OWF34782.1 - 0.059 13.5 0.5 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Peptidase M15 ADH_N PF08240.12 OWF34783.1 - 0.097 12.6 1.0 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.25 OWF34785.1 - 6.7e-48 163.3 0.0 4.7e-32 111.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34785.1 - 1.1e-27 96.9 0.0 1.3e-18 67.3 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase DUF641 PF04859.12 OWF34785.1 - 0.0037 17.6 1.1 0.0093 16.3 1.1 1.7 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) FTA2 PF13095.6 OWF34785.1 - 0.0039 16.8 0.2 0.44 10.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OWF34785.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 OWF34786.1 - 2.4e-47 161.3 0.1 1.1e-46 159.2 0.1 2.2 1 1 0 1 1 1 1 Kinase non-catalytic C-lobe domain FYVE PF01363.21 OWF34786.1 - 0.00097 19.2 6.6 0.0045 17.1 1.3 2.9 2 0 0 2 2 2 1 FYVE zinc finger Zf_RING PF16744.5 OWF34786.1 - 0.19 11.9 2.7 0.61 10.2 2.7 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 OWF34786.1 - 0.54 10.2 13.0 0.084 12.8 5.9 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) eIF-6 PF01912.18 OWF34787.1 - 1.6e-81 272.4 0.5 2.2e-81 272.0 0.5 1.2 1 0 0 1 1 1 1 eIF-6 family CARD PF00619.21 OWF34789.1 - 3.3e-09 36.7 3.3 5.1e-09 36.0 1.2 2.1 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 OWF34789.1 - 8.5e-06 25.7 0.5 1.9e-05 24.6 0.5 1.6 1 0 0 1 1 1 1 Caspase recruitment domain NPHI_C PF08469.10 OWF34789.1 - 0.28 11.2 2.9 0.43 10.5 2.9 1.3 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal CARD PF00619.21 OWF34790.1 - 1.1e-07 31.8 5.6 1.2e-07 31.7 0.5 3.5 3 0 0 3 3 3 1 Caspase recruitment domain CARD_2 PF16739.5 OWF34791.1 - 2e-08 34.1 0.4 1e-07 31.8 0.1 2.5 2 0 0 2 2 2 1 Caspase recruitment domain CARD PF00619.21 OWF34791.1 - 3.1e-08 33.5 4.4 3.4e-08 33.4 0.8 3.1 2 1 0 2 2 2 1 Caspase recruitment domain Cucumopine_C PF18631.1 OWF34791.1 - 0.099 12.6 0.0 10 6.1 0.0 2.8 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain TPR_19 PF14559.6 OWF34791.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 OWF34792.1 - 8.6e-12 44.9 6.4 8.6e-12 44.9 6.4 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF34792.1 - 8.8e-09 35.1 4.3 8.8e-09 35.1 4.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF34792.1 - 9.1e-08 31.8 3.4 9.1e-08 31.8 3.4 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF34792.1 - 1.2e-07 31.4 2.6 1.2e-07 31.4 2.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF34792.1 - 2.3e-07 31.0 4.6 2.3e-07 31.0 4.6 2.9 3 0 0 3 3 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF34792.1 - 1.8e-06 27.8 4.0 1.8e-06 27.8 4.0 2.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF34792.1 - 4.1e-06 26.9 4.1 4.1e-06 26.9 4.1 2.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF34792.1 - 4.9e-05 23.1 3.7 4.9e-05 23.1 3.7 2.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 OWF34792.1 - 0.00015 21.8 7.4 0.00015 21.8 7.4 2.6 2 0 0 2 2 2 1 B-box zinc finger zf-RING_11 PF17123.5 OWF34792.1 - 0.0014 18.3 5.7 0.0073 16.0 2.7 3.0 2 0 0 2 2 2 1 RING-like zinc finger NHL PF01436.21 OWF34792.1 - 0.0026 17.7 4.3 0.92 9.7 0.9 4.2 3 0 0 3 3 3 1 NHL repeat U-box PF04564.15 OWF34792.1 - 0.005 17.0 0.1 0.015 15.5 0.1 1.8 1 0 0 1 1 1 1 U-box domain PQQ_3 PF13570.6 OWF34792.1 - 0.031 14.8 0.7 0.096 13.2 0.5 1.9 2 0 0 2 2 1 0 PQQ-like domain FliT PF05400.13 OWF34792.1 - 0.072 13.9 3.6 0.24 12.2 3.6 1.9 1 0 0 1 1 1 0 Flagellar protein FliT SGL PF08450.12 OWF34792.1 - 0.08 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Zn_Tnp_IS91 PF14319.6 OWF34792.1 - 3.8 7.6 8.1 3.8 7.6 1.1 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.6 OWF34793.1 - 7.3e-12 45.1 6.9 7.3e-12 45.1 6.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF34793.1 - 2.8e-09 36.7 4.0 2.8e-09 36.7 4.0 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF34793.1 - 1.8e-07 31.4 5.0 1.8e-07 31.4 5.0 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF34793.1 - 1.8e-07 30.8 4.4 1.8e-07 30.8 4.4 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF34793.1 - 4.4e-07 29.7 2.8 4.4e-07 29.7 2.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF34793.1 - 4.9e-07 29.6 4.0 4.9e-07 29.6 4.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF34793.1 - 6.2e-06 26.3 3.7 6.2e-06 26.3 3.7 2.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 OWF34793.1 - 1.1e-05 25.5 5.1 1.1e-05 25.5 5.1 2.7 3 0 0 3 3 2 1 B-box zinc finger Prok-RING_4 PF14447.6 OWF34793.1 - 2.1e-05 24.3 3.9 2.1e-05 24.3 3.9 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF34793.1 - 0.0027 17.4 4.4 0.003 17.2 2.0 2.4 2 0 0 2 2 2 1 RING-like zinc finger U-box PF04564.15 OWF34793.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 U-box domain DUF2913 PF11140.8 OWF34793.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Apolipoprotein PF01442.18 OWF34793.1 - 0.44 10.4 4.3 1.7 8.5 4.3 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lon_C PF05362.13 OWF34794.1 - 1.8e-81 272.6 0.2 3.6e-81 271.6 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OWF34794.1 - 6.7e-26 91.4 0.2 1.3e-25 90.5 0.2 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OWF34794.1 - 2.4e-22 79.8 0.0 6.3e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF34794.1 - 6.6e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OWF34794.1 - 3.8e-05 23.5 0.0 7.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 OWF34794.1 - 0.00044 20.7 0.2 0.002 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 OWF34794.1 - 0.00097 18.1 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 OWF34794.1 - 0.0021 18.3 0.0 0.016 15.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OWF34794.1 - 0.0036 17.4 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 OWF34794.1 - 0.0076 16.2 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase RuvB_N PF05496.12 OWF34794.1 - 0.015 15.1 0.0 0.048 13.4 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 OWF34794.1 - 0.02 14.7 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OWF34794.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Imm70 PF15601.6 OWF34794.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 70 SKI PF01202.22 OWF34794.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.6 OWF34794.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Phage_TTP_12 PF16461.5 OWF34794.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP HEAT_EZ PF13513.6 OWF34795.1 - 4.3e-21 75.0 3.8 2.7e-08 34.1 0.1 8.9 10 1 1 11 11 9 3 HEAT-like repeat HEAT PF02985.22 OWF34795.1 - 4.3e-16 57.6 8.4 5.6e-05 23.1 0.0 8.0 7 0 0 7 7 6 2 HEAT repeat HEAT_2 PF13646.6 OWF34795.1 - 3.7e-13 49.7 0.5 0.044 14.2 0.0 6.7 5 3 1 6 6 6 3 HEAT repeats IBN_N PF03810.19 OWF34795.1 - 8.8e-13 48.0 2.2 2.9e-11 43.1 0.2 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 OWF34795.1 - 1.5e-11 44.7 3.2 0.082 13.5 0.0 7.8 7 3 1 8 8 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OWF34795.1 - 3e-09 36.8 0.1 0.058 12.9 0.0 4.9 3 3 0 4 4 4 2 CLASP N terminal Xpo1 PF08389.12 OWF34795.1 - 7.7e-07 29.3 1.1 0.27 11.3 0.0 6.0 6 0 0 6 6 6 1 Exportin 1-like protein BP28CT PF08146.12 OWF34795.1 - 1.9e-06 27.8 0.7 5.2 6.9 0.0 6.3 4 2 1 5 5 5 1 BP28CT (NUC211) domain Cnd1 PF12717.7 OWF34795.1 - 1.8e-05 24.8 4.8 0.33 11.0 0.0 4.8 5 2 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 OWF34795.1 - 2.4e-05 24.2 3.9 23 5.0 0.1 6.8 5 2 1 6 6 6 0 UME (NUC010) domain DUF3385 PF11865.8 OWF34795.1 - 6.1e-05 23.0 7.2 0.046 13.6 0.0 5.6 6 2 1 8 8 7 3 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 OWF34795.1 - 0.00037 19.2 4.3 0.22 10.1 0.0 4.5 5 2 0 5 5 5 1 Adaptin N terminal region RIX1 PF08167.12 OWF34795.1 - 0.00045 20.0 0.8 21 4.8 0.0 5.6 5 1 1 6 6 6 0 rRNA processing/ribosome biogenesis V-ATPase_H_N PF03224.14 OWF34795.1 - 0.00047 19.5 6.7 0.15 11.3 0.0 4.6 4 1 1 5 5 5 2 V-ATPase subunit H MMS19_C PF12460.8 OWF34795.1 - 0.0015 17.7 2.3 1 8.4 0.0 4.3 2 2 2 5 5 5 2 RNAPII transcription regulator C-terminal Cse1 PF08506.10 OWF34795.1 - 0.037 12.9 1.9 0.89 8.3 0.5 2.7 2 0 0 2 2 2 0 Cse1 TAN PF11640.8 OWF34795.1 - 0.056 13.6 1.0 17 5.5 0.0 4.1 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair Gcn1_N PF12074.8 OWF34795.1 - 0.077 12.3 0.2 0.33 10.2 0.0 2.2 3 0 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RTP1_C1 PF10363.9 OWF34795.1 - 0.22 11.7 4.2 28 4.9 0.0 4.9 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Importin_rep_4 PF18808.1 OWF34795.1 - 0.86 9.9 8.8 1.8 8.9 0.0 4.2 3 0 0 3 3 3 0 Importin repeat DUF4455 PF14643.6 OWF34795.1 - 1.2 7.7 4.0 1.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) SNAP PF14938.6 OWF34796.1 - 2.3e-26 92.9 7.3 3.2e-26 92.4 7.3 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OWF34796.1 - 6.5e-05 23.1 4.8 1.6 9.1 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 OWF34796.1 - 0.0019 17.4 4.7 0.0033 16.6 3.6 2.0 2 1 0 2 2 2 1 Spatacsin C-terminus AAA_lid_9 PF17871.1 OWF34796.1 - 0.0042 17.0 0.3 0.012 15.5 0.3 1.9 1 0 0 1 1 1 1 AAA lid domain DUF5481 PF17578.2 OWF34796.1 - 0.039 14.4 1.7 0.49 10.8 0.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5481) TPR_2 PF07719.17 OWF34796.1 - 0.04 14.0 14.2 8.6 6.7 1.5 6.0 5 1 0 6 6 6 0 Tetratricopeptide repeat DUF4200 PF13863.6 OWF34796.1 - 1.7 9.1 6.0 3.9 7.9 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ANAPC3 PF12895.7 OWF34796.1 - 5.4 7.3 9.1 5.6 7.3 0.3 3.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 4HBT_3 PF13622.6 OWF34797.1 - 4.7e-54 184.3 0.0 5.5e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OWF34797.1 - 6.2e-35 119.9 0.0 4.2e-26 91.4 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF3672 PF12421.8 OWF34797.1 - 0.064 13.2 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Fibronectin type III protein VWA PF00092.28 OWF34798.1 - 2.8e-81 272.0 11.5 7.7e-42 143.5 2.3 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF34798.1 - 1.1e-29 103.2 1.0 2.2e-15 57.2 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWC PF00093.18 OWF34798.1 - 1.1e-23 83.2 745.5 0.00058 20.1 7.3 34.7 34 1 0 34 34 34 28 von Willebrand factor type C domain VWA_3 PF13768.6 OWF34798.1 - 3.7e-06 26.9 0.0 0.00068 19.6 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain ShK PF01549.24 OWF34798.1 - 0.0021 18.6 9.7 0.0021 18.6 9.7 12.2 10 0 0 10 10 10 6 ShK domain-like Cytomega_UL20A PF05984.12 OWF34798.1 - 3.9 7.8 5.0 16 5.8 0.0 4.5 4 0 0 4 4 4 0 Cytomegalovirus UL20A protein CpeT PF06206.11 OWF34799.1 - 1.3e-19 70.9 0.2 2.6e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) VirK PF06903.12 OWF34799.1 - 1.2e-06 28.5 0.2 0.085 12.9 0.0 3.2 2 1 0 2 2 2 2 VirK protein TPR_12 PF13424.6 OWF34800.1 - 8.7e-22 77.2 2.7 6.5e-12 45.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF34800.1 - 7.6e-14 50.9 8.5 0.00014 21.5 0.1 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF4062 PF13271.6 OWF34800.1 - 8.8e-14 51.6 0.0 3.7e-13 49.6 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) TPR_10 PF13374.6 OWF34800.1 - 6.5e-13 48.1 8.4 6.3e-05 22.7 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF34800.1 - 5.7e-11 41.7 13.0 0.007 16.5 1.3 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OWF34800.1 - 1.2e-10 40.6 4.4 0.0028 17.6 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ATPase_2 PF01637.18 OWF34800.1 - 1.3e-09 38.3 0.3 4.7e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea TPR_2 PF07719.17 OWF34800.1 - 1.1e-08 34.5 8.0 0.17 12.1 0.4 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat AAA_22 PF13401.6 OWF34800.1 - 5.8e-08 33.1 0.0 8.1e-07 29.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF34800.1 - 2e-07 31.5 0.0 5.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OWF34800.1 - 3.7e-07 30.2 0.1 7.7e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain TPR_MalT PF17874.1 OWF34800.1 - 7.2e-05 22.3 0.1 0.00042 19.8 0.1 2.0 2 0 0 2 2 2 1 MalT-like TPR region KAP_NTPase PF07693.14 OWF34800.1 - 0.0016 17.8 0.0 0.13 11.4 0.0 2.6 1 1 1 2 2 2 1 KAP family P-loop domain ATPase PF06745.13 OWF34800.1 - 0.0019 17.6 0.0 0.04 13.3 0.0 2.8 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.22 OWF34800.1 - 0.0048 16.1 0.0 0.0098 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 OWF34800.1 - 0.04 13.5 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OWF34800.1 - 0.04 13.7 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OWF34800.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 OWF34800.1 - 0.089 12.1 0.0 0.29 10.4 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 OWF34800.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OWF34800.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 OWF34800.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 OWF34800.1 - 0.32 11.0 1.5 40 4.3 0.0 3.5 3 1 0 4 4 4 0 AAA domain ASC PF00858.24 OWF34801.1 - 7.5e-97 325.1 2.0 2.2e-96 323.5 2.0 1.7 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 OWF34802.1 - 2.1e-92 310.4 3.3 2.6e-92 310.1 3.3 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 OWF34803.1 - 3.2e-91 306.5 3.4 3.9e-91 306.2 3.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel 7tm_1 PF00001.21 OWF34803.1 - 0.01 15.2 0.8 0.017 14.5 0.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PBP1_TM PF14812.6 OWF34803.1 - 1.1 9.7 9.5 1.3 9.4 2.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRCT PF00533.26 OWF34804.1 - 9.2e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OWF34804.1 - 0.00037 20.9 0.0 0.00039 20.8 0.0 1.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RcsD_ABL PF16359.5 OWF34804.1 - 0.00069 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 RcsD-ABL domain TatD_DNase PF01026.21 OWF34805.1 - 1.9e-54 184.8 0.0 2.2e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase DDE_Tnp_IS66_C PF13817.6 OWF34805.1 - 0.16 12.3 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 IS66 C-terminal element Pkinase_Tyr PF07714.17 OWF34806.1 - 7.8e-89 297.4 0.0 9.9e-89 297.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF34806.1 - 1.4e-43 149.2 0.0 2e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF34806.1 - 1.1e-17 63.8 0.0 2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 OWF34806.1 - 2.5e-15 55.8 0.5 3.5e-14 52.1 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OWF34806.1 - 5.2e-11 42.2 0.4 1.2e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OWF34806.1 - 1.4e-05 24.7 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 OWF34806.1 - 0.0017 17.4 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF34806.1 - 0.0019 18.2 0.1 0.018 15.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF34806.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.16 OWF34806.1 - 0.06 13.5 0.0 0.72 10.0 0.0 2.3 2 1 1 3 3 3 0 ABC1 family SH3_10 PF17902.1 OWF34806.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Kdo PF06293.14 OWF34806.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4600 PF15372.6 OWF34807.1 - 0.00058 20.3 0.7 0.00058 20.3 0.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) GTP-bdg_M PF16360.5 OWF34807.1 - 0.067 13.8 3.0 0.077 13.6 0.5 2.3 1 1 0 2 2 2 0 GTP-binding GTPase Middle Region TRAF_BIRC3_bd PF16673.5 OWF34807.1 - 0.23 11.3 4.1 2 8.3 0.3 2.6 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain bZIP_1 PF00170.21 OWF34807.1 - 0.58 10.3 6.1 10 6.3 0.5 3.0 3 0 0 3 3 3 0 bZIP transcription factor FlxA PF14282.6 OWF34807.1 - 5.8 7.0 9.2 1.9 8.5 1.8 2.5 2 1 0 2 2 2 0 FlxA-like protein Pkinase PF00069.25 OWF34808.1 - 4.6e-17 62.2 0.0 7.4e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34808.1 - 1.2e-10 41.1 0.0 2.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF34808.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tcp10_C PF07202.13 OWF34809.1 - 7.6e-07 29.3 3.6 0.001 19.0 1.0 2.2 1 1 1 2 2 2 2 T-complex protein 10 C-terminus Rubi_NSP_C PF12601.8 OWF34809.1 - 4.7e-06 26.6 1.1 2.5 8.2 0.1 5.5 2 2 3 7 7 7 1 Rubivirus non-structural protein MTA_R1 PF17226.2 OWF34809.1 - 0.00012 22.1 11.9 7.8 6.7 0.0 6.3 3 3 5 8 8 8 2 MTA R1 domain DAG1 PF05454.11 OWF34809.1 - 0.00038 19.9 6.8 1.6 8.1 0.3 3.5 1 1 2 3 3 3 3 Dystroglycan (Dystrophin-associated glycoprotein 1) Plasmid_parti PF01672.16 OWF34809.1 - 0.043 14.5 13.3 47 4.7 0.0 5.5 4 2 1 6 6 6 0 Putative plasmid partition protein ApoC-I PF04691.12 OWF34809.1 - 0.17 11.8 1.1 26 4.9 0.1 3.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF2262 PF10020.9 OWF34809.1 - 1.8 9.0 5.5 7.1 7.0 1.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) Baculo_Y142 PF04913.12 OWF34809.1 - 3.2 6.3 8.8 3.2 6.3 1.9 2.6 1 1 2 3 3 3 0 Baculovirus Y142 protein T2SSB PF16537.5 OWF34809.1 - 4.6 6.9 17.5 14 5.4 0.2 5.7 2 1 5 8 8 8 0 Type II secretion system protein B DUF4916 PF16262.5 OWF34809.1 - 8.3 5.9 10.8 9.1 5.8 0.5 3.9 1 1 5 6 6 6 0 Domain of unknown function (DUF4916) DUF4614 PF15391.6 OWF34810.1 - 2.6e-46 158.0 9.7 2.6e-46 158.0 9.7 5.4 4 3 3 7 7 7 1 Domain of unknown function (DUF4614) DSPc PF00782.20 OWF34811.1 - 2.4e-12 46.8 0.0 3.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF34811.1 - 2.1e-05 24.7 0.3 5.6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OWF34811.1 - 0.00013 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 OWF34811.1 - 0.0071 15.9 0.3 0.037 13.6 0.3 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OWF34811.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF3950 PF13132.6 OWF34811.1 - 0.32 10.8 1.9 2.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) F5_F8_type_C PF00754.25 OWF34812.1 - 0.00012 22.2 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain DUF3377 PF11857.8 OWF34812.1 - 0.12 12.3 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) 7tm_1 PF00001.21 OWF34813.1 - 7.2e-31 107.5 16.6 1e-30 107.0 16.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF34813.1 - 1.9e-10 40.8 15.7 3.1e-10 40.1 15.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pkinase PF00069.25 OWF34814.1 - 4.1e-09 36.2 0.0 0.00029 20.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DUF4011 PF13195.6 OWF34814.1 - 0.037 13.9 0.0 0.08 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) Pkinase PF00069.25 OWF34815.1 - 1.4e-29 103.3 0.0 1.9e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34815.1 - 4.2e-17 62.3 0.0 5.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF34815.1 - 2.8e-08 33.0 0.1 4.1e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OWF34815.1 - 0.00064 19.7 0.0 0.022 14.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OWF34816.1 - 2.4e-19 69.7 0.1 3.2e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34816.1 - 8.8e-09 35.0 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF34816.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 OWF34817.1 - 1.8e-14 53.7 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34817.1 - 6.2e-08 32.2 0.0 1.7e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF34817.1 - 0.038 13.3 0.1 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OWF34817.1 - 0.046 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OWF34818.1 - 3.5e-23 82.3 0.0 4.6e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34818.1 - 6e-10 38.8 0.0 7.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF34818.1 - 0.0058 15.5 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OWF34818.1 - 0.012 15.0 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 OWF34818.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Galactosyl_T PF01762.21 OWF34819.1 - 2.8e-38 131.7 0.4 5.9e-38 130.7 0.4 1.6 1 0 0 1 1 1 1 Galactosyltransferase DUF4912 PF16258.5 OWF34819.1 - 0.57 10.4 4.6 16 5.7 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4912) Galactosyl_T PF01762.21 OWF34820.1 - 2.4e-39 135.2 0.4 4e-39 134.5 0.4 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF34820.1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Fringe-like DUF4795 PF16043.5 OWF34820.1 - 0.87 9.1 7.1 3.3 7.3 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Galactosyl_T PF01762.21 OWF34821.1 - 1.5e-36 126.0 2.7 2.3e-36 125.4 2.7 1.3 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 OWF34822.1 - 3.7e-38 131.3 2.2 6.3e-38 130.6 2.2 1.4 1 0 0 1 1 1 1 Galactosyltransferase PALP PF00291.25 OWF34823.1 - 2.7e-76 256.8 3.1 3.5e-76 256.4 3.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 OWF34823.1 - 0.00082 19.1 0.0 0.0027 17.4 0.0 1.9 1 0 0 1 1 1 1 ACT domain ADH_zinc_N PF00107.26 OWF34823.1 - 0.029 14.3 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ferritin_2 PF13668.6 OWF34823.1 - 0.03 14.5 0.1 0.34 11.1 0.1 2.4 2 1 1 3 3 3 0 Ferritin-like domain ACT_4 PF13291.6 OWF34823.1 - 0.066 13.8 0.2 0.18 12.4 0.0 1.8 2 0 0 2 2 2 0 ACT domain Melittin PF01372.17 OWF34824.1 - 0.11 12.5 9.5 30 4.8 0.1 4.9 2 2 3 5 5 5 0 Melittin AWPM-19 PF05512.11 OWF34824.1 - 0.12 12.6 0.5 8.8 6.5 0.0 2.5 1 1 1 2 2 2 0 AWPM-19-like family Retinin_C PF04527.12 OWF34825.1 - 1.8e-07 31.3 65.5 1.9 8.8 0.5 12.2 2 2 6 8 8 8 5 Drosophila Retinin like protein Plasmodium_HRP PF05403.11 OWF34825.1 - 0.075 12.8 0.0 4.4 7.0 0.0 2.7 3 1 0 3 3 3 0 Plasmodium histidine-rich protein (HRPII/III) Retinin_C PF04527.12 OWF34826.1 - 3.6e-14 52.8 81.9 0.16 12.2 0.7 17.3 2 2 8 10 10 10 6 Drosophila Retinin like protein DUF4573 PF15140.6 OWF34826.1 - 0.0074 16.1 0.0 2.3 8.0 0.0 3.8 2 2 2 4 4 4 2 Domain of unknown function (DUF4573) Rieske_2 PF13806.6 OWF34826.1 - 0.3 11.0 21.8 27 4.8 0.1 8.8 2 2 6 11 11 11 0 Rieske-like [2Fe-2S] domain RhoGAP PF00620.27 OWF34827.1 - 3.8e-46 156.7 0.1 1e-45 155.2 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 OWF34827.1 - 1.2e-05 25.5 0.3 4.9e-05 23.5 0.3 2.2 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 OWF34827.1 - 3 8.2 11.9 12 6.2 11.9 2.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EF-hand_2 PF09068.11 OWF34829.1 - 2.7e-29 101.8 1.3 6.2e-29 100.6 1.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 OWF34829.1 - 2.3e-20 72.8 0.0 7e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 OWF34829.1 - 1.3e-16 60.2 10.2 2.2e-16 59.4 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type WW PF00397.26 OWF34829.1 - 2.5e-06 27.5 1.2 5.1e-06 26.5 1.2 1.5 1 0 0 1 1 1 1 WW domain JAKMIP_CC3 PF16034.5 OWF34829.1 - 0.004 17.1 4.7 0.023 14.6 2.7 2.6 2 0 0 2 2 2 1 JAKMIP CC3 domain Med4 PF10018.9 OWF34829.1 - 0.0078 15.9 2.0 0.015 14.9 2.0 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Nnf1 PF03980.14 OWF34829.1 - 0.013 15.9 1.1 0.031 14.7 1.1 1.7 1 0 0 1 1 1 0 Nnf1 TSC22 PF01166.18 OWF34829.1 - 0.026 14.8 3.6 0.097 13.0 3.6 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 OWF34829.1 - 0.14 11.9 5.6 0.32 10.8 5.6 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 OWF34829.1 - 0.38 11.3 8.5 1.1 9.8 8.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 OWF34829.1 - 2.3 8.9 8.6 0.32 11.6 3.3 2.4 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 OWF34829.1 - 3.8 8.0 8.9 0.32 11.4 3.6 2.0 2 0 0 2 2 1 0 Cell division protein ZapB bZIP_2 PF07716.15 OWF34829.1 - 3.8 7.7 14.0 5.2 7.2 6.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Kelch_1 PF01344.25 OWF34830.1 - 1.3e-76 251.9 23.0 1.8e-17 62.6 0.0 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 OWF34830.1 - 1.9e-43 145.4 6.1 2.2e-09 37.2 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OWF34830.1 - 3.4e-32 110.1 9.8 4.6e-08 33.2 0.2 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.15 OWF34830.1 - 6.5e-32 109.7 0.8 1.5e-31 108.6 0.8 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 OWF34830.1 - 1.9e-31 108.6 0.1 3.7e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 OWF34830.1 - 5.9e-31 105.3 6.4 7.5e-10 38.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OWF34830.1 - 8.1e-19 67.4 3.2 0.00011 22.2 0.1 6.3 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF34830.1 - 0.00013 21.9 9.6 1.2 9.2 0.0 5.1 5 0 0 5 5 5 2 Kelch motif DUF3342 PF11822.8 OWF34830.1 - 0.0021 18.2 0.4 1 9.6 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3342) MFS_2 PF13347.6 OWF34831.1 - 8.3e-106 354.1 26.5 9.5e-106 353.9 26.5 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein CCDC24 PF15669.5 OWF34832.1 - 3.3e-56 190.4 0.2 3.3e-56 190.4 0.2 2.2 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 24 family Pkinase PF00069.25 OWF34833.1 - 2.6e-67 227.0 0.0 4.7e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34833.1 - 1.7e-43 148.8 0.0 2.8e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 OWF34833.1 - 1.5e-06 28.5 11.1 1.5e-06 28.5 11.1 2.5 2 0 0 2 2 2 1 Ring finger domain Kinase-like PF14531.6 OWF34833.1 - 5.1e-05 22.7 0.0 0.05 12.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OWF34833.1 - 0.00025 19.9 0.0 0.0009 18.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase SWIM PF04434.17 OWF34833.1 - 0.0012 18.4 0.1 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger zf-ANAPC11 PF12861.7 OWF34833.1 - 0.002 18.1 3.4 0.0055 16.7 3.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Kdo PF06293.14 OWF34833.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYDLN_acid PF09538.10 OWF34833.1 - 3 8.6 8.3 1.5 9.6 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-rbx1 PF12678.7 OWF34833.1 - 3.1 8.1 10.1 13 6.2 10.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain SSB PF00436.25 OWF34834.1 - 0.12 12.4 0.1 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Single-strand binding protein family Fe-S_biosyn PF01521.20 OWF34835.1 - 2.4e-20 72.8 0.1 3e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 OWF34835.1 - 0.013 15.7 0.1 0.018 15.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3853) KH_6 PF15985.5 OWF34836.1 - 3.4e-13 49.7 0.5 7e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 OWF34836.1 - 9.8e-08 31.8 0.2 2e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Methyltransf_25 PF13649.6 OWF34837.1 - 1.2e-07 32.3 0.0 4.2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 OWF34837.1 - 3.8e-07 29.8 0.0 7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 OWF34837.1 - 2.7e-06 26.5 0.0 4.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 OWF34837.1 - 5.4e-06 26.1 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 OWF34837.1 - 1e-05 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.12 OWF34837.1 - 4e-05 24.2 0.0 9.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 OWF34837.1 - 0.00026 20.9 1.3 0.00084 19.3 0.1 2.1 2 0 0 2 2 2 1 PRMT5 oligomerisation domain Methyltransf_18 PF12847.7 OWF34837.1 - 0.00032 20.7 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OWF34837.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 OWF34837.1 - 0.0026 17.6 0.0 0.0051 16.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF34837.1 - 0.0034 17.0 0.1 0.0083 15.8 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 GidB PF02527.15 OWF34837.1 - 0.062 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 OWF34837.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CARM1 PF11531.8 OWF34837.1 - 0.12 12.6 1.2 0.26 11.5 1.2 1.5 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal SPICE PF15678.5 OWF34838.1 - 2.1e-67 228.3 20.6 2.1e-67 228.3 20.6 2.5 2 1 0 2 2 2 1 Centriole duplication and mitotic chromosome congression Pox_H7 PF04787.12 OWF34838.1 - 0.099 13.2 0.8 0.31 11.6 0.2 2.0 2 0 0 2 2 2 0 Late protein H7 LPP PF04728.13 OWF34838.1 - 4.3 7.8 7.7 0.4 11.1 1.1 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SNF2_N PF00176.23 OWF34839.1 - 1.7e-72 244.1 2.2 1.7e-72 244.1 2.2 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF34839.1 - 3.9e-19 69.0 0.0 4.7e-18 65.5 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 OWF34839.1 - 3.9e-19 68.7 18.6 3.9e-19 68.7 18.6 3.8 4 0 0 4 4 4 1 HSA BRK PF07533.16 OWF34839.1 - 6.4e-19 67.3 0.0 1.6e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 BRK domain SnAC PF14619.6 OWF34839.1 - 2.6e-18 66.4 9.6 2.6e-18 66.4 9.6 5.4 5 1 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.25 OWF34839.1 - 7.5e-18 64.4 2.4 2.9e-17 62.5 0.3 2.9 3 0 0 3 3 3 1 Bromodomain QLQ PF08880.11 OWF34839.1 - 2.1e-11 43.3 0.0 5.4e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 OWF34839.1 - 4.2e-09 36.6 0.2 4.2e-09 36.6 0.2 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF34839.1 - 0.0018 18.1 1.0 0.0036 17.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Brix PF04427.18 OWF34840.1 - 6.2e-39 134.1 0.0 8.4e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain MIF4G PF02854.19 OWF34841.1 - 6.3e-13 48.8 2.3 1.2e-12 48.0 2.3 1.4 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 OWF34841.1 - 1.4e-07 30.7 3.4 0.00031 20.2 0.5 3.0 3 0 0 3 3 3 2 Ataxin-2 C-terminal region CSN8_PSD8_EIF3K PF10075.9 OWF34841.1 - 0.045 13.7 0.2 0.097 12.6 0.2 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family PAS_5 PF07310.13 OWF34841.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 PAS domain MMACHC PF16690.5 OWF34842.1 - 1.5e-98 328.8 0.1 1.7e-98 328.6 0.1 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family ICMT PF04140.14 OWF34842.1 - 0.15 12.5 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2475 PF10629.9 OWF34843.1 - 1.3e-30 105.4 3.4 2.1e-30 104.7 3.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) EF-hand_7 PF13499.6 OWF34844.1 - 7.3e-13 48.8 11.8 1.1e-10 41.8 4.7 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF34844.1 - 3.2e-09 35.7 12.2 0.001 18.5 0.9 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF34844.1 - 8.3e-09 34.7 9.7 0.003 17.3 0.2 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF34844.1 - 0.0007 19.4 11.9 0.037 13.9 1.2 3.0 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF34844.1 - 0.0042 17.4 1.3 0.011 16.0 1.3 2.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region U3_assoc_6 PF08640.11 OWF34844.1 - 0.041 13.9 0.4 0.1 12.7 0.4 1.7 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 SMP_2 PF10144.9 OWF34844.1 - 0.042 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin EF-hand_4 PF12763.7 OWF34844.1 - 0.091 12.7 9.5 0.12 12.3 1.0 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand VPS28 PF03997.12 OWF34845.1 - 1.7e-67 226.8 1.4 2e-67 226.6 1.4 1.0 1 0 0 1 1 1 1 VPS28 protein DUF1128 PF06569.11 OWF34845.1 - 0.067 13.2 0.8 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) DDRGK PF09756.9 OWF34846.1 - 0.78 9.3 23.0 1.6 8.3 23.0 1.4 1 0 0 1 1 1 0 DDRGK domain Lipase PF00151.19 OWF34849.1 - 1.2e-91 307.5 0.0 1.4e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 OWF34849.1 - 5e-05 23.8 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain PAN_1 PF00024.26 OWF34850.1 - 3.1e-10 39.9 2.9 4.5e-10 39.4 2.9 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF34850.1 - 0.032 14.1 1.1 0.064 13.2 1.1 1.6 1 1 0 1 1 1 0 PAN domain TSP_1 PF00090.19 OWF34851.1 - 4.1e-209 676.8 270.4 6e-14 52.0 5.7 18.7 19 0 0 19 19 19 18 Thrombospondin type 1 domain Hepsin-SRCR PF09272.10 OWF34851.1 - 0.014 15.9 0.1 0.038 14.5 0.1 1.7 1 0 0 1 1 1 0 Hepsin, SRCR domain Lipase PF00151.19 OWF34852.1 - 7.8e-107 357.5 0.0 9.4e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 OWF34852.1 - 1.4e-06 28.8 0.0 2.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain Lipase_3 PF01764.25 OWF34852.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 OWF34852.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 OWF34852.1 - 0.19 12.3 3.8 0.64 10.6 3.7 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family F5_F8_type_C PF00754.25 OWF34853.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain DUF872 PF05915.12 OWF34853.1 - 0.12 12.5 0.1 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) MPM1 PF17234.2 OWF34853.1 - 0.17 12.1 0.1 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Profilin PF00235.19 OWF34854.1 - 3e-32 111.6 0.0 3.4e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Profilin Glyco_transf_21 PF13506.6 OWF34856.1 - 2.6e-50 170.3 0.0 3.4e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OWF34856.1 - 4.8e-20 72.4 0.0 6.1e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OWF34856.1 - 1.2e-12 48.2 3.4 2e-12 47.4 3.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OWF34856.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 ATP13 PF12921.7 OWF34856.1 - 0.022 14.6 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase expression TauD PF02668.16 OWF34857.1 - 8.5e-30 104.4 0.0 1.1e-29 104.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GKAP PF03359.13 OWF34858.1 - 3.4e-34 119.0 7.2 3.4e-34 119.0 7.2 4.2 4 1 2 6 6 6 1 Guanylate-kinase-associated protein (GKAP) protein F-box PF00646.33 OWF34859.1 - 2e-07 30.7 0.0 4.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OWF34859.1 - 3.8e-07 29.9 0.4 6.9e-07 29.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 OWF34859.1 - 0.00028 20.4 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box LRR_4 PF12799.7 OWF34859.1 - 0.067 13.6 0.8 5.7 7.5 0.3 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) ARD PF03079.14 OWF34859.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Nucleoporin_N PF08801.11 OWF34860.1 - 3.1e-98 329.3 0.0 4.7e-98 328.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OWF34860.1 - 1.7e-30 106.3 1.4 2.3e-30 105.9 1.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nup160 PF11715.8 OWF34860.1 - 0.086 11.5 0.0 0.18 10.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 IF-2B PF01008.17 OWF34861.1 - 4e-82 275.6 0.1 4.6e-82 275.4 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fanconi_C PF02106.15 OWF34862.1 - 6.7e-28 97.7 4.8 4.4e-16 58.7 1.4 2.2 2 0 0 2 2 2 2 Fanconi anaemia group C protein CHASE6_C PF17150.4 OWF34862.1 - 0.0018 18.9 0.2 2.9 8.6 0.1 3.2 3 0 0 3 3 3 2 C-terminal domain of two-partite extracellular sensor domain CREPT PF16566.5 OWF34862.1 - 0.015 15.5 1.1 0.064 13.4 0.2 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4744 PF15918.5 OWF34863.1 - 0.041 14.7 3.5 1.2 10.0 0.5 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4744) Nod1 PF17114.5 OWF34863.1 - 0.16 12.1 5.8 0.36 11.0 1.0 2.0 1 1 1 2 2 2 0 Gef2-related medial cortical node protein Nod1 Snf7 PF03357.21 OWF34863.1 - 0.38 10.3 1.1 0.56 9.8 0.6 1.5 1 1 0 1 1 1 0 Snf7 SatRNA_48 PF17485.2 OWF34863.1 - 2.7 7.0 9.5 1.6 7.8 2.3 2.0 1 1 1 2 2 2 0 Satellite RNA 48 kDa protein DUF1011 PF06237.12 OWF34864.1 - 5 7.5 22.7 2.8 8.3 8.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1011) I-set PF07679.16 OWF34865.1 - 2.9e-15 56.1 0.0 1.1e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF34865.1 - 5.3e-15 55.8 0.1 1.2e-06 29.0 0.0 3.0 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 OWF34865.1 - 2.6e-10 40.3 0.0 2.6e-06 27.5 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF34865.1 - 1.5e-08 34.8 0.0 0.0017 18.7 0.0 3.0 2 2 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF34865.1 - 2.3e-08 34.1 0.2 9.6e-07 29.0 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain ObR_Ig PF18589.1 OWF34865.1 - 0.026 14.9 0.0 0.065 13.6 0.0 1.7 1 1 0 1 1 1 0 Obesity receptor immunoglobulin like domain Ank_2 PF12796.7 OWF34866.1 - 1e-14 54.9 0.0 1.4e-07 32.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) LEM PF03020.15 OWF34866.1 - 3e-09 36.3 0.1 5.7e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 LEM domain Ank_5 PF13857.6 OWF34866.1 - 2e-06 28.0 0.1 9.4e-06 25.8 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF34866.1 - 2.8e-06 27.7 0.0 0.048 14.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF34866.1 - 8.1e-06 26.1 2.1 0.18 12.3 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat GAS PF13851.6 OWF34867.1 - 0.0004 19.8 3.9 0.0004 19.8 3.9 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding ArAE_2_N PF10337.9 OWF34867.1 - 0.008 15.3 4.0 0.0091 15.1 4.0 1.1 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal Fez1 PF06818.15 OWF34867.1 - 0.0082 16.6 8.0 0.0082 16.6 8.0 2.3 1 1 1 2 2 2 1 Fez1 Med14 PF08638.11 OWF34867.1 - 0.01 15.3 2.8 0.065 12.6 2.8 1.9 1 1 0 1 1 1 0 Mediator complex subunit MED14 DUF4201 PF13870.6 OWF34867.1 - 0.032 14.0 17.6 0.028 14.1 4.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) IBV_3A PF03617.13 OWF34867.1 - 0.075 13.0 0.7 0.15 12.0 0.4 1.7 2 0 0 2 2 1 0 IBV 3A protein GAT PF03127.14 OWF34867.1 - 0.081 13.2 6.8 2.5 8.4 0.2 2.4 2 1 0 2 2 2 0 GAT domain FUSC PF04632.12 OWF34867.1 - 0.12 10.9 0.2 0.14 10.7 0.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.6 OWF34867.1 - 0.27 11.4 15.2 0.38 10.9 13.5 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YtxH PF12732.7 OWF34867.1 - 0.39 11.3 3.6 7.4 7.2 3.6 2.6 1 1 0 1 1 1 0 YtxH-like protein DivIC PF04977.15 OWF34867.1 - 0.44 10.4 8.0 3.3 7.5 0.6 3.4 3 1 1 4 4 4 0 Septum formation initiator T2SSM PF04612.12 OWF34867.1 - 0.49 10.4 3.4 3.1 7.8 0.4 2.7 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M WXG100 PF06013.12 OWF34867.1 - 0.83 9.9 5.2 1.1 9.5 0.5 3.0 3 1 1 4 4 3 0 Proteins of 100 residues with WXG AKNA PF12443.8 OWF34867.1 - 0.94 10.2 11.3 0.13 13.0 2.5 3.2 1 1 3 4 4 4 0 AT-hook-containing transcription factor Spc42p PF11544.8 OWF34867.1 - 1.5 8.9 11.9 1.1 9.3 0.6 2.9 2 2 0 2 2 2 0 Spindle pole body component Spc42p APG6_N PF17675.1 OWF34867.1 - 2.4 8.7 19.8 1.6 9.3 8.2 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region RhoGEF67_u1 PF16615.5 OWF34867.1 - 3 8.4 5.0 0.86 10.2 1.3 2.0 2 1 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 DUF724 PF05266.14 OWF34867.1 - 3.4 7.5 14.8 2.1 8.1 8.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2203 PF09969.9 OWF34867.1 - 3.7 8.3 7.1 7 7.4 3.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec20 PF03908.13 OWF34867.1 - 4 7.4 8.0 1.5 8.8 0.6 2.6 2 1 0 2 2 2 0 Sec20 Seryl_tRNA_N PF02403.22 OWF34867.1 - 4.3 7.6 13.7 25 5.1 2.9 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain OrfB_IS605 PF01385.19 OWF34867.1 - 4.4 7.6 8.4 3.2 8.0 2.5 2.4 1 1 1 2 2 2 0 Probable transposase MPS2 PF17060.5 OWF34867.1 - 7.5 5.7 13.8 2.2 7.5 10.1 1.7 1 1 1 2 2 2 0 Monopolar spindle protein 2 DHR10 PF18595.1 OWF34867.1 - 9.3 6.3 20.7 1 9.5 2.1 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Stathmin PF00836.19 OWF34868.1 - 0.054 13.5 0.6 0.25 11.3 0.3 2.0 2 0 0 2 2 2 0 Stathmin family Ion_trans PF00520.31 OWF34869.1 - 3.6e-35 121.4 17.4 4.8e-35 121.0 17.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF34869.1 - 8.9e-08 32.0 11.9 8.9e-08 32.0 11.9 2.4 2 0 0 2 2 2 1 Ion channel DUF3460 PF11943.8 OWF34869.1 - 0.0052 17.0 2.9 0.013 15.8 2.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3460) UCMA PF17085.5 OWF34869.1 - 0.065 13.3 0.1 0.065 13.3 0.1 1.8 2 1 0 2 2 2 0 Unique cartilage matrix associated protein BTB_2 PF02214.22 OWF34870.1 - 1.8e-18 66.6 0.0 2.4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain DUF1974 PF09317.11 OWF34873.1 - 5.8e-05 22.8 0.0 7.9 6.0 0.0 7.8 2 2 0 2 2 2 1 Domain of unknown function (DUF1974) T2SSF PF00482.23 OWF34873.1 - 6.1e-05 23.0 2.3 89 3.1 0.0 10.4 4 1 1 7 7 7 1 Type II secretion system (T2SS), protein F PhoLip_ATPase_C PF16212.5 OWF34874.1 - 5.4e-81 272.0 34.5 5.4e-81 272.0 34.5 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OWF34874.1 - 1.1e-25 89.0 6.7 1.1e-25 89.0 6.7 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OWF34874.1 - 2.7e-11 43.4 0.1 3.5e-10 39.8 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OWF34874.1 - 1.4e-10 41.8 0.5 0.00013 22.3 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OWF34874.1 - 0.00013 21.6 0.1 0.00013 21.6 0.1 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OWF34874.1 - 0.00035 20.4 0.0 0.004 16.9 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 OWF34874.1 - 0.026 14.0 1.1 0.036 13.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) TPH PF13868.6 OWF34875.1 - 6.5e-27 94.0 127.4 6.5e-27 94.0 127.4 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain SKA1 PF07160.12 OWF34876.1 - 1.2e-52 179.2 10.2 1.4e-52 178.9 10.2 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF3161 PF11362.8 OWF34876.1 - 0.0073 16.3 1.3 0.041 13.9 0.3 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3161) CLZ PF16526.5 OWF34876.1 - 0.016 15.5 2.4 0.069 13.5 1.8 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 OWF34876.1 - 0.022 14.9 3.6 0.022 14.9 3.6 2.2 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding MtaB PF12176.8 OWF34876.1 - 0.079 11.7 3.5 0.051 12.4 1.6 1.7 1 1 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit BRE1 PF08647.11 OWF34876.1 - 0.64 10.1 9.4 0.54 10.4 2.8 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Cyclin_N PF00134.23 OWF34880.1 - 1e-45 154.6 1.1 1e-45 154.6 1.1 2.0 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF34880.1 - 1.9e-36 124.7 1.1 1.9e-36 124.7 1.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Focadhesin PF11229.8 OWF34881.1 - 1.7e-111 373.3 0.1 3.2e-111 372.4 0.1 1.5 1 0 0 1 1 1 1 Focadhesin DUF3730 PF12530.8 OWF34881.1 - 3.4e-50 170.7 1.6 3.9e-47 160.8 0.1 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF3730) Pico_P2B PF01552.17 OWF34881.1 - 9.7 6.4 7.5 0.95 9.7 0.0 3.0 4 0 0 4 4 4 0 Picornavirus 2B protein IBR PF01485.21 OWF34882.1 - 5.9e-20 71.3 44.5 1.2e-13 51.0 9.7 4.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OWF34882.1 - 0.0011 18.7 1.9 0.0011 18.7 1.9 5.2 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF34882.1 - 0.0012 18.7 2.0 0.0012 18.7 2.0 5.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF34882.1 - 0.0029 17.9 3.2 0.0029 17.9 3.2 5.1 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF34882.1 - 0.11 12.7 0.5 0.086 13.0 2.8 5.2 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING DUF5102 PF17104.5 OWF34882.1 - 0.59 10.1 2.8 1.2 9.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Glyco_hydro_30 PF02055.16 OWF34883.1 - 6.6e-154 512.1 0.6 7.9e-154 511.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OWF34883.1 - 2e-11 43.9 0.0 3.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 OWF34883.1 - 2.2e-10 40.2 0.1 3.4e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_cc PF11790.8 OWF34883.1 - 0.15 11.6 1.4 0.27 10.7 0.1 1.9 2 1 0 2 2 2 0 Glycosyl hydrolase catalytic core Linker_histone PF00538.19 OWF34884.1 - 5.4e-28 97.2 0.2 5.4e-28 97.2 0.2 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family Myotub-related PF06602.14 OWF34885.1 - 2.2e-46 158.4 1.4 2.2e-46 158.4 1.4 2.5 2 1 0 3 3 3 1 Myotubularin-like phosphatase domain 3-PAP PF12578.8 OWF34885.1 - 3.1e-10 39.9 0.7 7.6e-10 38.6 0.7 1.6 1 0 0 1 1 1 1 Myotubularin-associated protein Forkhead PF00250.18 OWF34887.1 - 7.3e-32 109.5 0.1 1.6e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Forkhead domain DUF2976 PF11190.8 OWF34888.1 - 0.029 14.2 0.0 0.076 12.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) DUF1422 PF07226.11 OWF34888.1 - 0.072 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) PMP1_2 PF08114.11 OWF34888.1 - 0.088 12.6 0.6 0.32 10.8 0.6 2.0 1 0 0 1 1 1 0 ATPase proteolipid family Lectin_C PF00059.21 OWF34890.1 - 4.3e-10 40.3 0.0 5.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain TPR_8 PF13181.6 OWF34891.1 - 5.5e-09 35.6 15.8 0.0052 16.9 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OWF34891.1 - 2.3e-08 33.9 3.2 0.047 14.1 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF34891.1 - 5.7e-08 32.9 3.0 2.6 9.1 0.0 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF34891.1 - 7.3e-08 32.0 14.5 0.011 15.8 0.0 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF34891.1 - 2.8e-07 30.1 13.7 0.024 14.5 0.0 6.8 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF34891.1 - 4e-06 26.9 0.5 4.5e-05 23.5 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF34891.1 - 5.1e-06 26.9 2.4 0.38 11.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF34891.1 - 1.2e-05 24.9 3.4 0.97 9.2 0.0 5.3 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.6 OWF34891.1 - 3.6e-05 24.0 9.0 0.0022 18.3 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF34891.1 - 4.2e-05 24.1 0.4 0.0034 18.0 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF34891.1 - 0.0011 19.0 0.3 0.29 11.3 0.1 3.7 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OWF34891.1 - 0.0084 16.7 6.2 4.5 8.1 0.5 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OWF34891.1 - 0.0098 16.4 2.4 0.026 15.0 0.1 2.6 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation TPR_7 PF13176.6 OWF34891.1 - 0.036 14.1 6.3 31 4.9 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.10 OWF34891.1 - 0.073 12.1 1.2 18 4.2 0.1 3.1 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) PspA_IM30 PF04012.12 OWF34891.1 - 1.1 8.8 6.4 8.2 5.9 0.4 3.1 3 1 0 3 3 3 0 PspA/IM30 family PAS_10 PF13596.6 OWF34892.1 - 0.16 12.6 0.1 0.5 11.0 0.1 1.8 1 1 0 1 1 1 0 PAS domain Ank_2 PF12796.7 OWF34893.1 - 6.4e-17 61.9 0.2 1.7e-13 51.0 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF34893.1 - 4.5e-13 49.0 2.1 7.8e-05 22.9 0.3 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OWF34893.1 - 4.8e-12 46.1 0.3 7.8e-05 23.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF34893.1 - 2.3e-09 36.7 1.1 0.0052 17.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OWF34893.1 - 4.1e-08 33.3 1.8 0.0022 18.3 0.0 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Death PF00531.22 OWF34893.1 - 7.4e-06 26.0 1.9 1.8e-05 24.8 0.3 2.5 3 0 0 3 3 3 1 Death domain Ank_2 PF12796.7 OWF34894.1 - 1e-66 221.5 18.8 1.3e-13 51.3 0.2 14.9 12 2 3 15 15 15 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF34894.1 - 6.9e-46 154.1 13.3 5e-06 27.0 0.0 13.9 12 1 2 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF34894.1 - 2.1e-33 110.6 21.0 0.022 15.2 0.0 19.7 24 0 0 24 24 24 8 Ankyrin repeat Ank_5 PF13857.6 OWF34894.1 - 1.3e-23 82.8 11.6 0.0012 19.1 0.0 15.0 13 3 5 18 18 18 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF34894.1 - 1.4e-23 82.2 18.0 0.023 15.1 0.0 16.6 19 1 1 20 20 20 6 Ankyrin repeat Pox_LP_H2 PF03356.15 OWF34894.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Viral late protein H2 SGL PF08450.12 OWF34895.1 - 9.2e-33 113.8 0.0 1.1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF34895.1 - 0.13 12.3 0.0 40 4.5 0.0 4.1 5 0 0 5 5 5 0 NHL repeat Reg_prop PF07494.11 OWF34895.1 - 3 8.4 4.7 32 5.2 0.1 4.0 3 1 1 4 4 4 0 Two component regulator propeller RICTOR_N PF14664.6 OWF34896.1 - 2.6e-104 349.2 0.2 5.6e-104 348.1 0.1 1.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 OWF34896.1 - 1.8e-33 115.2 1.5 1.2e-31 109.3 0.0 3.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 OWF34896.1 - 1.4e-29 102.1 1.7 2.4e-27 95.0 0.7 3.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 OWF34896.1 - 7.8e-29 99.5 2.0 1.4e-26 92.3 0.2 3.9 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain TMEM132D_N PF15705.5 OWF34896.1 - 0.11 12.4 0.1 19 5.1 0.0 3.0 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term ATP-synt_DE_N PF02823.16 OWF34897.1 - 8.1e-16 57.7 0.1 2.2e-15 56.3 0.0 1.7 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PAN_1 PF00024.26 OWF34898.1 - 2.4e-36 123.6 45.0 1.5e-07 31.2 3.4 5.7 5 0 0 5 5 5 5 PAN domain Ependymin PF00811.18 OWF34898.1 - 0.0015 18.8 0.0 0.18 12.1 0.0 4.2 3 1 0 3 3 3 1 Ependymin PAN_4 PF14295.6 OWF34898.1 - 0.0015 18.4 35.0 0.48 10.4 0.2 5.8 5 0 0 5 5 5 4 PAN domain PAN_2 PF08276.11 OWF34898.1 - 5.4 7.2 33.8 2.7 8.2 2.4 5.5 5 0 0 5 5 5 0 PAN-like domain Methyltransf_21 PF05050.12 OWF34899.1 - 3.4e-05 23.9 0.0 6.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain MTS PF05175.14 OWF34899.1 - 0.00027 20.5 0.1 0.00048 19.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OWF34899.1 - 0.0014 18.4 0.1 0.0056 16.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF34899.1 - 0.0032 18.1 0.0 0.0078 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OWF34899.1 - 0.0047 16.4 0.1 0.0076 15.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OWF34899.1 - 0.013 16.1 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OWF34899.1 - 0.025 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.11 OWF34899.1 - 0.046 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 OWF34899.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) TehB PF03848.14 OWF34899.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB rRNA_methylase PF06962.12 OWF34899.1 - 0.17 11.8 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Putative rRNA methylase zf-B_box PF00643.24 OWF34900.1 - 0.59 10.3 16.8 0.038 14.1 11.0 2.1 2 0 0 2 2 2 0 B-box zinc finger NHL PF01436.21 OWF34900.1 - 2.2 8.5 6.5 26 5.1 0.1 4.1 5 0 0 5 5 5 0 NHL repeat Minor_capsid_2 PF11114.8 OWF34903.1 - 0.045 13.8 0.3 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Minor capsid protein GIT_SHD PF08518.11 OWF34903.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Pkinase PF00069.25 OWF34904.1 - 7.9e-51 172.9 0.0 1e-50 172.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34904.1 - 5.5e-46 156.9 0.0 6.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF34904.1 - 0.00014 21.3 0.0 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF34904.1 - 0.0044 15.9 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OWF34904.1 - 0.0092 15.6 0.0 0.033 13.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family FRG2 PF15315.6 OWF34905.1 - 0.0073 16.5 6.3 0.015 15.5 6.3 1.5 1 0 0 1 1 1 1 Facioscapulohumeral muscular dystrophy candidate 2 DUF45 PF01863.17 OWF34905.1 - 0.71 9.9 9.5 0.27 11.2 6.9 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 AMP-binding PF00501.28 OWF34906.1 - 5.2e-97 325.1 0.0 6.3e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OWF34906.1 - 3.2e-21 75.0 1.4 3.2e-21 75.0 1.4 2.7 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OWF34906.1 - 3.7e-21 75.9 0.5 1.2e-20 74.2 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zinc_ribbon_6 PF14599.6 OWF34907.1 - 6.9e-26 90.0 2.0 6.9e-26 90.0 2.0 3.8 2 1 1 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 OWF34907.1 - 4.1e-17 62.4 24.6 4.1e-17 62.4 24.6 4.6 3 2 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.6 OWF34907.1 - 3.7e-09 36.8 5.5 3.7e-09 36.8 5.5 5.5 5 1 0 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF34907.1 - 9.8e-06 25.3 4.9 9.8e-06 25.3 4.9 5.7 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF34907.1 - 5.1e-05 22.9 5.6 5.1e-05 22.9 5.6 4.1 6 0 0 6 6 6 1 RING-like zinc finger zf-RING_4 PF14570.6 OWF34907.1 - 0.00073 19.3 3.5 0.00073 19.3 3.5 4.9 5 2 1 6 6 6 1 RING/Ubox like zinc-binding domain Hpr_kinase_N PF02603.16 OWF34907.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase N terminus Amnionless PF14828.6 OWF34908.1 - 0.00095 18.1 1.4 0.0096 14.8 0.2 2.2 1 1 1 2 2 2 2 Amnionless Flu_M2 PF00599.17 OWF34908.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) DUF1180 PF06679.12 OWF34908.1 - 0.018 15.5 1.0 0.036 14.5 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) zf-C2H2_8 PF15909.5 OWF34908.1 - 0.036 14.3 0.4 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon Ly49 PF08391.10 OWF34908.1 - 0.14 12.5 0.5 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region SKG6 PF08693.10 OWF34908.1 - 0.84 9.1 7.6 2 7.9 7.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4834 PF16118.5 OWF34908.1 - 2.3 9.2 4.6 25 5.9 4.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF397 PF04149.12 OWF34909.1 - 0.016 15.3 1.9 13 5.9 0.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF397) UvsY PF11056.8 OWF34910.1 - 4.9 7.5 7.8 15 6.0 0.2 3.1 1 1 1 3 3 3 0 Recombination, repair and ssDNA binding protein UvsY DUF3522 PF12036.8 OWF34911.1 - 4.9e-65 219.4 19.0 9.3e-65 218.4 19.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Pox_A14 PF05767.12 OWF34911.1 - 5.1 7.3 6.6 2.9 8.1 0.1 3.5 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Choline_transpo PF04515.12 OWF34912.1 - 6.3e-98 328.0 29.0 6.3e-98 328.0 29.0 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF295 PF03478.18 OWF34912.1 - 0.0063 16.1 0.1 0.026 14.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF295) DUF2573 PF10835.8 OWF34912.1 - 0.033 14.5 0.1 0.077 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) PsbN PF02468.15 OWF34912.1 - 2.2 8.2 4.0 9.3 6.2 2.9 2.8 1 1 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Diphthamide_syn PF01866.17 OWF34913.1 - 1.7e-100 336.4 0.1 2.1e-100 336.1 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HTH_28 PF13518.6 OWF34914.1 - 0.013 15.6 2.6 74 3.6 0.0 6.2 3 2 8 11 11 11 0 Helix-turn-helix domain TRAM1 PF08390.11 OWF34914.1 - 0.031 13.9 48.2 3.2 7.5 0.9 8.4 1 1 12 13 13 13 0 TRAM1-like protein OLF PF02191.16 OWF34914.1 - 4.1 6.9 13.9 30 4.0 0.3 4.0 1 1 3 5 5 5 0 Olfactomedin-like domain Plectin PF00681.20 OWF34915.1 - 3.3e-195 631.7 30.1 0.00017 21.4 0.0 66.5 55 15 15 70 70 70 43 Plectin repeat Spectrin PF00435.21 OWF34915.1 - 4.9e-192 624.8 267.4 1.1e-15 58.0 0.3 32.0 31 0 0 31 31 31 28 Spectrin repeat GAS2 PF02187.17 OWF34915.1 - 9.9e-32 108.9 0.4 2.6e-31 107.5 0.4 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_7 PF13499.6 OWF34915.1 - 9.9e-09 35.5 0.1 9.7e-08 32.4 0.1 3.0 1 0 0 1 1 1 1 EF-hand domain pair OCRE PF17780.1 OWF34915.1 - 9.2e-08 32.0 0.5 10 6.3 0.0 9.2 10 0 0 10 10 10 1 OCRE domain EF-hand_6 PF13405.6 OWF34915.1 - 9.1e-06 25.2 0.0 0.011 15.6 0.0 3.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OWF34915.1 - 1.2e-05 24.5 0.0 0.0016 17.9 0.0 3.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF34915.1 - 0.00011 22.0 0.6 0.00068 19.4 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF34915.1 - 0.0023 17.4 0.0 0.0085 15.5 0.0 2.1 1 0 0 1 1 1 1 EF hand Zmiz1_N PF18028.1 OWF34915.1 - 0.17 12.2 8.4 8.7 6.7 0.2 6.3 5 0 0 5 5 5 0 Zmiz1 N-terminal tetratricopeptide repeat domain Fic PF02661.18 OWF34915.1 - 1.9 9.5 14.9 34 5.4 0.0 8.1 8 0 0 8 8 6 0 Fic/DOC family DUF3741 PF12552.8 OWF34915.1 - 2.5 8.1 5.8 2.6 8.1 0.6 4.2 4 0 0 4 4 3 0 Protein of unknown function (DUF3741) NfI_DNAbd_pre-N PF10524.9 OWF34916.1 - 8.7e-26 89.5 3.1 1.6e-25 88.7 3.1 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 OWF34916.1 - 9.4e-12 45.1 0.3 1.9e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 MH1 domain CTF_NFI PF00859.18 OWF34916.1 - 2.2e-08 34.4 39.4 2.3e-05 24.5 39.0 3.7 1 1 0 1 1 1 1 CTF/NF-I family transcription modulation region MULE PF10551.9 OWF34916.1 - 0.2 12.1 0.0 0.41 11.1 0.0 1.4 1 0 0 1 1 1 0 MULE transposase domain zinc_ribbon_9 PF14369.6 OWF34917.1 - 0.0086 16.3 31.1 0.042 14.1 1.2 5.6 5 1 1 6 6 6 4 zinc-ribbon Cript PF10235.9 OWF34917.1 - 4.9 7.8 15.0 6.8 7.3 0.5 3.8 1 1 3 4 4 4 0 Microtubule-associated protein CRIPT DHHC PF01529.20 OWF34918.1 - 3.9e-31 107.9 10.9 3.9e-31 107.9 10.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase FGGY_C PF02782.16 OWF34919.1 - 4e-43 147.5 0.0 6.5e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OWF34919.1 - 4.8e-24 85.3 0.9 2.3e-23 83.0 0.9 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OWF34919.1 - 0.00076 19.1 1.9 0.0036 16.8 1.0 2.4 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DNA_pol_A_exo1 PF01612.20 OWF34919.1 - 0.029 14.1 0.1 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 3'-5' exonuclease DUF4258 PF14076.6 OWF34919.1 - 0.13 12.7 2.2 3.5 8.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4258) Herpes_TK_C PF08465.10 OWF34919.1 - 0.29 10.9 1.2 0.59 9.9 0.3 2.0 1 1 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Ran_BP1 PF00638.18 OWF34920.1 - 2.1e-15 57.0 0.0 4.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain RMI2 PF16100.5 OWF34921.1 - 1.8e-28 98.9 0.2 2e-28 98.8 0.2 1.0 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 OWF34921.1 - 0.006 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_fac-A_3 PF08661.11 OWF34921.1 - 0.024 15.0 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Replication factor A protein 3 MacB_PCD PF12704.7 OWF34921.1 - 0.046 14.1 0.0 0.05 14.0 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain COesterase PF00135.28 OWF34922.1 - 4.2e-132 441.6 0.0 4.8e-132 441.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF34922.1 - 0.00021 21.2 0.4 0.00082 19.3 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold 7tm_1 PF00001.21 OWF34923.1 - 9.6e-30 103.8 19.6 1.2e-29 103.5 19.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF34923.1 - 4.7e-12 46.1 21.6 7.6e-12 45.4 21.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF34923.1 - 9.9e-06 25.1 19.2 1.7e-05 24.3 19.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF34923.1 - 0.0029 17.4 12.9 0.0045 16.8 12.8 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srd PF10317.9 OWF34923.1 - 0.0071 15.6 16.8 0.01 15.0 16.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd 7TM_GPCR_Srb PF02175.16 OWF34923.1 - 0.23 11.2 11.8 0.066 13.0 7.7 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srb Amj PF10997.8 OWF34923.1 - 1 8.6 8.1 0.067 12.5 2.8 1.6 2 0 0 2 2 2 0 Alternate to MurJ DUF4430 PF14478.6 OWF34924.1 - 0.12 13.0 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Cobalamin_bind PF01122.19 OWF34925.1 - 6.9e-06 25.2 0.4 1.7e-05 23.9 0.4 1.6 1 1 0 1 1 1 1 Eukaryotic cobalamin-binding protein DSL PF01414.19 OWF34927.1 - 1.2e-16 60.8 11.7 1.2e-16 60.8 11.7 2.3 2 0 0 2 2 2 1 Delta serrate ligand MNNL PF07657.13 OWF34927.1 - 1.1e-07 31.8 1.3 1.1e-07 31.8 1.3 2.5 2 1 1 3 3 3 1 N terminus of Notch ligand Toxin_20 PF08089.11 OWF34927.1 - 0.38 10.9 2.9 1.1 9.5 2.9 1.8 1 0 0 1 1 1 0 Huwentoxin-II family DNAP_B_exo_N PF08452.10 OWF34928.1 - 0.25 10.8 4.9 6.2 6.3 2.4 2.5 2 0 0 2 2 2 0 DNA polymerase family B exonuclease domain, N-terminal Choline_transpo PF04515.12 OWF34929.1 - 2.1e-104 349.3 35.3 2.1e-104 349.3 35.3 2.9 3 0 0 3 3 3 2 Plasma-membrane choline transporter PNK3P PF08645.11 OWF34930.1 - 7.5e-50 168.8 0.0 1.3e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OWF34930.1 - 2.7e-14 53.5 0.0 6.5e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OWF34930.1 - 0.00094 18.7 0.2 0.56 9.6 0.1 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 OWF34930.1 - 0.0094 15.2 0.0 0.11 11.7 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_22 PF13401.6 OWF34930.1 - 0.063 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nucleic_acid_bd PF13820.6 OWF34931.1 - 1.9e-31 108.8 0.0 8.6e-31 106.7 0.0 2.2 1 0 0 1 1 1 1 Putative nucleic acid-binding region Annexin PF00191.20 OWF34932.1 - 5.5e-77 253.8 8.1 3.1e-23 81.6 0.2 4.3 4 1 0 4 4 4 4 Annexin HNH_4 PF13395.6 OWF34932.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease Myb_DNA-bind_7 PF15963.5 OWF34932.1 - 0.05 13.5 0.5 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Myb DNA-binding like BTB PF00651.31 OWF34933.1 - 8.4e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF34934.1 - 0.00023 21.4 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF34936.1 - 1.5e-05 25.2 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PBP1_TM PF14812.6 OWF34936.1 - 0.089 13.2 1.8 0.1 13.0 0.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRM_1 PF00076.22 OWF34937.1 - 9.3e-07 28.6 0.0 2.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF34937.1 - 9.3e-05 22.2 0.0 0.0009 19.1 0.0 2.2 1 1 0 1 1 1 1 Occluded RNA-recognition motif Ndr PF03096.14 OWF34937.1 - 0.17 10.6 0.2 0.23 10.1 0.2 1.1 1 0 0 1 1 1 0 Ndr family Mito_carr PF00153.27 OWF34938.1 - 8.7e-31 105.7 2.9 7.8e-10 38.6 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Cadherin PF00028.17 OWF34939.1 - 9.7e-13 48.4 17.9 0.0079 16.6 0.4 7.0 6 2 0 6 6 6 5 Cadherin domain Herpes_UL73 PF03554.13 OWF34939.1 - 0.62 10.1 3.5 15 5.6 0.1 2.7 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein HYR PF02494.16 OWF34939.1 - 4.6 7.6 9.5 0.73 10.2 1.2 3.4 3 0 0 3 3 3 0 HYR domain DUF5011 PF16403.5 OWF34939.1 - 6.3 7.0 10.2 1.9 8.7 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) Cadherin PF00028.17 OWF34940.1 - 1.2e-15 57.8 12.7 1.5e-05 25.3 0.0 6.1 5 2 0 5 5 5 5 Cadherin domain Sen15 PF09631.10 OWF34940.1 - 0.11 12.9 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Sen15 protein DDE_Tnp_4 PF13359.6 OWF34941.1 - 3.8e-31 107.9 0.0 6e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OWF34941.1 - 1e-05 25.2 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein MADF_DNA_bdg PF10545.9 OWF34943.1 - 1.2e-08 35.2 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like V-ATPase_H_N PF03224.14 OWF34945.1 - 5.8e-108 360.9 10.6 1.3e-107 359.8 10.1 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OWF34945.1 - 2.5e-48 163.0 1.0 1.8e-45 153.8 0.0 3.3 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 OWF34945.1 - 9.2e-08 31.8 0.2 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Armadillo-like Arm PF00514.23 OWF34945.1 - 0.00057 19.8 1.0 8.2 6.6 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DRIM PF07539.12 OWF34945.1 - 0.00075 17.9 1.8 0.0036 15.7 0.8 2.1 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT_2 PF13646.6 OWF34945.1 - 0.0032 17.8 0.6 0.32 11.4 0.0 4.2 4 3 1 5 5 5 1 HEAT repeats DUF2326 PF10088.9 OWF34945.1 - 0.0045 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2326) L51_S25_CI-B8 PF05047.16 OWF34945.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Telomere_reg-2 PF10193.9 OWF34945.1 - 0.28 11.7 3.4 0.46 11.0 0.1 2.7 3 0 0 3 3 3 0 Telomere length regulation protein HEAT PF02985.22 OWF34945.1 - 0.36 11.2 3.0 2 8.9 0.0 3.6 4 0 0 4 4 3 0 HEAT repeat IZUMO PF15005.6 OWF34945.1 - 0.69 10.4 5.9 0.2 12.1 1.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Mito_carr PF00153.27 OWF34946.1 - 9.8e-70 230.6 0.5 1.1e-22 79.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF34946.1 - 1.4e-05 24.4 0.0 0.024 13.8 0.0 3.2 2 1 0 2 2 2 2 Gammaproteobacterial serine protease DUF3300 PF11737.8 OWF34946.1 - 0.095 12.2 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) FMN_red PF03358.15 OWF34947.1 - 8.5e-25 87.3 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OWF34947.1 - 0.00092 19.0 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold mTERF PF02536.14 OWF34948.1 - 3.3e-16 59.1 0.4 5e-16 58.5 0.4 1.2 1 0 0 1 1 1 1 mTERF Peptidase_Prp PF04327.12 OWF34948.1 - 0.16 12.2 0.9 14 6.0 0.2 2.6 2 0 0 2 2 2 0 Cysteine protease Prp UNC45-central PF11701.8 OWF34949.1 - 5.5e-26 91.4 0.5 5.5e-26 91.4 0.5 4.3 4 2 0 5 5 5 1 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 OWF34949.1 - 2.4e-13 49.3 14.5 2.8e-05 23.7 1.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF34949.1 - 6.4e-12 44.6 13.0 0.00075 19.4 0.2 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF34949.1 - 3.2e-07 30.5 3.5 6.8e-07 29.5 1.6 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF34949.1 - 4e-06 26.4 6.0 0.017 14.8 0.2 3.1 1 1 2 3 3 3 2 TPR repeat TPR_19 PF14559.6 OWF34949.1 - 3.8e-05 24.1 8.8 0.00052 20.5 1.1 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF34949.1 - 0.00037 20.6 5.3 0.0013 18.9 5.3 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OWF34949.1 - 0.0005 19.9 1.5 0.44 10.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Arm PF00514.23 OWF34949.1 - 0.0007 19.5 9.7 19 5.5 0.1 7.9 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat TPR_9 PF13371.6 OWF34949.1 - 0.0055 16.8 0.2 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF34949.1 - 0.012 15.8 10.7 1.1 9.7 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF34949.1 - 0.013 16.1 1.7 0.079 13.6 0.2 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat DUF3361 PF11841.8 OWF34949.1 - 0.014 15.4 0.2 0.014 15.4 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) Herpes_capsid PF06112.11 OWF34949.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TPR_14 PF13428.6 OWF34949.1 - 0.042 14.7 1.1 1.8 9.6 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OWF34949.1 - 0.11 12.0 1.0 0.18 11.3 0.1 1.9 2 0 0 2 2 2 0 SHNi-TPR Drf_GBD PF06371.13 OWF34949.1 - 0.33 10.5 4.9 1.2 8.7 0.0 3.1 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain TPR_6 PF13174.6 OWF34949.1 - 0.47 11.2 2.1 40 5.2 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat HTH_28 PF13518.6 OWF34949.1 - 0.53 10.5 1.7 25 5.1 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain TPR_17 PF13431.6 OWF34949.1 - 1.1 9.8 2.9 4.9 7.7 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0122 PF04297.14 OWF34949.1 - 3.9 7.8 8.5 2.1 8.6 0.4 3.3 3 0 0 3 3 2 0 Putative helix-turn-helix protein, YlxM / p13 like APG6_N PF17675.1 OWF34950.1 - 0.22 12.0 45.7 0.099 13.2 17.5 3.8 2 1 2 4 4 4 0 Apg6 coiled-coil region Atg14 PF10186.9 OWF34950.1 - 0.7 8.9 33.8 18 4.3 33.0 2.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 OWF34950.1 - 1.1 8.6 22.1 0.27 10.5 4.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 OWF34950.1 - 4.6 7.6 32.9 0.17 12.2 3.2 3.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Rad21_Rec8_N PF04825.13 OWF34951.1 - 1.1e-40 138.2 0.0 2.4e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OWF34951.1 - 1.1e-14 53.4 0.2 7.3e-14 50.8 0.1 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 OWF34951.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Segregation and condensation protein ScpA P5CR_dimer PF14748.6 OWF34952.1 - 2.9e-41 139.9 1.1 2.9e-41 139.9 1.1 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OWF34952.1 - 2.9e-19 69.4 0.2 5.9e-19 68.5 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 OWF34952.1 - 9.5e-05 22.4 0.6 0.00016 21.7 0.6 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 OWF34952.1 - 0.0047 17.1 0.1 0.0078 16.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.15 OWF34952.1 - 0.053 12.4 0.2 0.17 10.7 0.0 1.9 2 1 1 3 3 3 0 Ornithine cyclodeaminase/mu-crystallin family PDH PF02153.17 OWF34952.1 - 0.066 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Peptidase_C2 PF00648.21 OWF34953.1 - 4e-40 137.7 0.0 5.9e-37 127.3 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 OWF34953.1 - 1.1e-19 71.1 0.0 3.8e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 Calpain large subunit, domain III Tis11B_N PF04553.12 OWF34953.1 - 0.16 12.5 3.8 3.1 8.4 0.1 2.5 1 1 0 2 2 2 0 Tis11B like protein, N terminus Tetraspanin PF00335.20 OWF34954.1 - 6.1e-33 114.4 9.5 7e-33 114.2 9.5 1.0 1 0 0 1 1 1 1 Tetraspanin family EF-hand_1 PF00036.32 OWF34955.1 - 5.1e-36 119.5 13.5 3e-09 35.8 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF34955.1 - 2.7e-34 117.4 5.8 1.3e-16 60.8 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF34955.1 - 4.1e-29 98.0 8.1 7.8e-08 31.7 0.1 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OWF34955.1 - 2.9e-25 86.6 12.4 9.6e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF34955.1 - 3.1e-24 84.6 9.6 1.3e-10 41.0 0.6 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 OWF34955.1 - 1.3e-17 63.8 0.1 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF34955.1 - 1.4e-11 44.7 1.0 5.4e-06 26.7 0.3 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF34955.1 - 6e-10 39.0 1.3 2.3e-05 24.3 0.3 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF34955.1 - 6.9e-05 22.8 0.3 0.25 11.3 0.0 3.6 2 2 2 4 4 4 1 Caleosin related protein EF-hand_11 PF08976.11 OWF34955.1 - 0.00015 22.6 0.2 0.19 12.6 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain TerB PF05099.13 OWF34955.1 - 0.00094 19.2 0.4 0.25 11.3 0.2 2.4 2 1 0 2 2 2 1 Tellurite resistance protein TerB RabGAP-TBC PF00566.18 OWF34955.1 - 0.0015 18.3 1.6 0.0037 16.9 1.6 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF2666 PF10869.8 OWF34955.1 - 0.0032 17.7 2.1 0.013 15.7 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2666) Alpha_adaptin_C PF02296.16 OWF34955.1 - 0.0043 17.2 0.3 0.089 13.0 0.0 2.2 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain DUF2267 PF10025.9 OWF34955.1 - 0.0076 16.5 0.3 0.62 10.4 0.1 2.3 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) SCO1-SenC PF02630.14 OWF34955.1 - 0.0081 16.1 0.2 0.019 14.9 0.1 1.5 1 1 0 1 1 1 1 SCO1/SenC Dockerin_1 PF00404.18 OWF34955.1 - 0.011 15.9 2.7 4.4 7.6 0.1 3.4 1 1 1 2 2 2 0 Dockerin type I domain UPF0154 PF03672.13 OWF34955.1 - 0.015 15.3 0.0 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF853 PF05872.12 OWF34955.1 - 0.035 12.7 1.5 0.42 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF3549 PF12069.8 OWF34955.1 - 0.057 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Styelin PF17562.2 OWF34955.1 - 0.083 13.3 0.2 0.083 13.3 0.2 2.9 3 0 0 3 3 3 0 Styelin HMG_box_2 PF09011.10 OWF34955.1 - 0.73 10.5 5.5 0.29 11.7 0.4 2.7 2 2 0 2 2 2 0 HMG-box domain VWC PF00093.18 OWF34957.1 - 4.6e-11 42.9 161.8 0.016 15.5 12.1 9.4 9 0 0 9 9 9 8 von Willebrand factor type C domain ZU5 PF00791.20 OWF34958.1 - 9.2e-19 67.6 0.0 2.2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 OWF34958.1 - 4.7e-11 42.7 0.3 1.1e-10 41.5 0.1 1.8 2 0 0 2 2 2 1 Death domain UPA PF17217.3 OWF34958.1 - 2.6e-09 37.1 0.1 5e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 UPA domain Cadherin PF00028.17 OWF34959.1 - 7.4e-11 42.3 1.7 2.9e-05 24.4 0.0 3.6 4 0 0 4 4 4 2 Cadherin domain He_PIG PF05345.12 OWF34959.1 - 0.051 13.8 2.3 3.8 7.8 0.5 3.3 3 0 0 3 3 3 0 Putative Ig domain TMEM154 PF15102.6 OWF34959.1 - 0.078 12.9 0.1 0.21 11.5 0.1 1.8 1 1 0 1 1 1 0 TMEM154 protein family Glyco_transf_10 PF00852.19 OWF34960.1 - 9.6e-49 165.5 2.3 1.9e-48 164.5 2.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF34960.1 - 1.1e-14 54.8 0.0 3.5e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal p450 PF00067.22 OWF34961.1 - 2.2e-78 264.1 0.0 2.5e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gly_transf_sug PF04488.15 OWF34962.1 - 1.2e-12 48.3 0.3 1e-11 45.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OWF34962.1 - 0.00011 21.7 0.2 0.00074 18.9 0.2 1.9 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 OWF34962.1 - 0.00042 19.8 1.8 0.0011 18.5 1.2 2.1 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein PlyB_C PF18684.1 OWF34962.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Pleurotolysin B C-terminal domain EGF PF00008.27 OWF34963.1 - 4.8e-11 42.7 40.1 1.4e-05 25.3 8.7 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 OWF34963.1 - 0.0015 18.8 44.0 0.0097 16.3 12.0 3.5 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 OWF34963.1 - 0.021 15.4 30.7 0.16 12.6 4.7 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF ArAE_2_N PF10337.9 OWF34965.1 - 6.4e-05 22.2 0.5 9.3e-05 21.6 0.5 1.2 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal Phage_int_SAM_5 PF13102.6 OWF34965.1 - 0.013 15.9 0.6 0.039 14.3 0.5 1.9 2 0 0 2 2 2 0 Phage integrase SAM-like domain RB_A PF01858.17 OWF34965.1 - 0.027 14.3 0.5 0.027 14.3 0.5 2.1 2 1 0 2 2 2 0 Retinoblastoma-associated protein A domain Chalcone_2 PF16035.5 OWF34965.1 - 0.031 14.0 1.7 0.058 13.2 1.0 1.8 1 1 1 2 2 2 0 Chalcone isomerase like Pkinase PF00069.25 OWF34966.1 - 1.8e-68 230.7 0.0 2.4e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34966.1 - 4.9e-49 166.9 0.0 7e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 OWF34966.1 - 1.9e-23 82.2 4.5 4.1e-23 81.2 4.5 1.6 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 OWF34966.1 - 2.2e-08 33.3 0.0 4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OWF34966.1 - 0.0066 15.4 0.3 0.042 12.8 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Abi_2 PF07751.11 OWF34966.1 - 0.026 14.8 0.1 0.078 13.2 0.0 1.8 2 0 0 2 2 2 0 Abi-like protein Lactamase_B PF00753.27 OWF34967.1 - 3.1e-18 66.5 1.2 7.3e-18 65.3 1.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 OWF34967.1 - 1.1e-10 41.3 0.0 2.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 OWF34967.1 - 0.00087 18.9 0.1 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RIFIN PF02009.16 OWF34967.1 - 0.0057 16.6 5.0 0.011 15.7 5.0 1.3 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 OWF34967.1 - 0.038 14.3 1.4 0.13 12.6 0.5 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Lactamase_B_3 PF13483.6 OWF34967.1 - 0.043 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain TMEM154 PF15102.6 OWF34967.1 - 0.12 12.3 11.0 0.095 12.6 6.9 2.5 1 1 1 2 2 2 0 TMEM154 protein family Glyco_transf_10 PF00852.19 OWF34969.1 - 3.1e-47 160.5 1.6 3.1e-47 160.5 1.6 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF34969.1 - 1e-20 74.2 0.3 2.6e-20 72.9 0.3 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Dna2 PF08696.11 OWF34970.1 - 4e-59 199.8 0.9 1.1e-58 198.4 0.9 1.8 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 OWF34970.1 - 2e-47 161.4 0.0 5.8e-47 159.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OWF34970.1 - 1.2e-30 107.2 0.5 5.6e-19 69.0 0.1 4.9 3 3 1 4 4 4 2 AAA domain AAA_19 PF13245.6 OWF34970.1 - 8e-14 52.2 0.5 8.3e-12 45.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OWF34970.1 - 3.1e-13 49.9 0.0 8e-12 45.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OWF34970.1 - 2.2e-05 24.3 2.9 0.16 11.7 0.1 4.0 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OWF34970.1 - 0.0053 16.1 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 OWF34970.1 - 0.03 14.9 0.1 1.3 9.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain PKI PF02827.16 OWF34971.1 - 8.2e-15 54.8 0.2 1e-14 54.5 0.2 1.1 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor EF-hand_1 PF00036.32 OWF34972.1 - 2.3e-29 98.7 15.7 2.3e-07 29.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF34972.1 - 1.1e-28 99.4 11.5 1.4e-14 54.3 2.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF34972.1 - 6.7e-24 81.7 11.4 5.2e-07 29.1 1.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF34972.1 - 1.6e-22 77.9 15.1 7.9e-07 28.3 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF34972.1 - 3.7e-17 61.9 21.4 1.2e-08 34.7 2.8 3.9 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF34972.1 - 2e-10 41.0 1.8 0.00016 21.9 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OWF34972.1 - 6.7e-10 39.2 1.3 1.1e-05 25.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OWF34972.1 - 9.7e-05 22.5 4.4 0.038 14.2 0.4 3.7 2 2 2 4 4 4 1 Dockerin type I domain EF-hand_10 PF14788.6 OWF34972.1 - 0.002 17.9 0.3 0.036 13.9 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_14 PF17959.1 OWF34972.1 - 0.0032 17.8 0.9 0.028 14.8 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OWF34972.1 - 0.0047 16.9 4.7 0.28 11.2 0.6 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 OWF34972.1 - 0.0097 16.0 0.4 0.048 13.7 0.1 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SurA_N_3 PF13624.6 OWF34972.1 - 0.03 14.1 0.2 0.65 9.8 0.0 2.2 1 1 0 2 2 2 0 SurA N-terminal domain EcoR124_C PF12008.8 OWF34972.1 - 0.033 13.8 2.6 0.12 12.0 2.6 1.9 1 1 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal AAA_17 PF13207.6 OWF34972.1 - 0.036 14.5 0.6 0.065 13.7 0.3 1.6 1 1 0 1 1 1 0 AAA domain EF-hand_11 PF08976.11 OWF34972.1 - 0.076 13.9 0.4 7.3 7.5 0.0 2.3 1 1 0 2 2 2 0 EF-hand domain Glyco_transf_10 PF00852.19 OWF34973.1 - 1.4e-45 155.2 6.3 2.8e-45 154.2 6.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF34973.1 - 3.3e-25 88.7 0.2 3.3e-25 88.7 0.2 2.0 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal LRR_6 PF13516.6 OWF34975.1 - 2.8e-06 26.9 9.8 2 8.7 0.1 6.0 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 OWF34975.1 - 0.13 12.8 15.1 11 7.0 0.1 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat Pkinase PF00069.25 OWF34976.1 - 1.5e-55 188.4 0.0 2.1e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF34976.1 - 4.5e-22 78.6 0.0 9.3e-22 77.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OWF34976.1 - 0.00012 22.1 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OWF34976.1 - 0.016 14.8 0.5 0.029 14.0 0.5 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OWF34976.1 - 0.035 13.7 0.2 0.29 10.7 0.0 2.6 3 1 0 3 3 3 0 RIO1 family YrbL-PhoP_reg PF10707.9 OWF34976.1 - 0.041 13.4 3.8 3.4 7.1 0.0 2.6 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Kdo PF06293.14 OWF34976.1 - 0.079 12.3 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5334 PF17268.2 OWF34976.1 - 0.14 12.4 0.3 0.89 9.9 0.3 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5334) SAE2 PF08573.10 OWF34977.1 - 4.2e-06 27.8 0.4 4.2e-06 27.8 0.4 5.5 4 2 1 5 5 5 2 DNA repair protein endonuclease SAE2/CtIP C-terminus UIM PF02809.20 OWF34977.1 - 0.0017 18.2 2.6 0.0082 16.0 2.6 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4407 PF14362.6 OWF34977.1 - 0.014 14.8 1.1 0.014 14.8 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NYD-SP28 PF14772.6 OWF34977.1 - 0.017 15.2 4.7 0.13 12.3 0.1 3.3 2 0 0 2 2 2 0 Sperm tail SKA2 PF16740.5 OWF34977.1 - 0.052 13.3 2.6 0.077 12.8 1.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4047 PF13256.6 OWF34977.1 - 0.15 12.2 0.6 0.48 10.6 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) PolC_DP2 PF03833.13 OWF34978.1 - 1.5 6.6 4.2 1.7 6.4 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Syndecan PF01034.20 OWF34979.1 - 4.8e-28 96.9 0.5 8.2e-28 96.1 0.5 1.4 1 0 0 1 1 1 1 Syndecan domain Thyroglobulin_1 PF00086.18 OWF34979.1 - 5.6e-23 80.4 6.9 1.5e-12 46.9 1.4 2.4 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Glycophorin_A PF01102.18 OWF34979.1 - 0.0011 19.2 0.4 0.0053 17.0 0.0 2.0 2 0 0 2 2 2 1 Glycophorin A DUF4366 PF14283.6 OWF34979.1 - 0.033 14.3 0.8 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) EphA2_TM PF14575.6 OWF34979.1 - 0.041 14.8 0.3 4.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2062 PF09835.9 OWF34979.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) BORCS6 PF10157.9 OWF34980.1 - 0.0078 16.5 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 SlyX PF04102.12 OWF34980.1 - 0.043 14.4 0.6 0.068 13.8 0.6 1.2 1 0 0 1 1 1 0 SlyX ZapB PF06005.12 OWF34980.1 - 0.05 14.1 0.0 0.071 13.6 0.0 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Lipase_GDSL_2 PF13472.6 OWF34982.1 - 3e-06 27.8 0.0 6.1e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2635 PF10948.8 OWF34983.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Glyco_hydro_42 PF02449.15 OWF34983.1 - 0.095 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Beta-galactosidase NTP_transferase PF00483.23 OWF34984.1 - 6.7e-31 107.7 0.0 9.7e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OWF34984.1 - 6.2e-09 35.2 5.7 1e-06 28.2 0.1 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OWF34984.1 - 0.00044 20.6 0.0 0.00071 20.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 OWF34984.1 - 0.12 10.5 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Glyco_transf_64 PF09258.10 OWF34985.1 - 2.7e-91 305.2 0.3 4.4e-91 304.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 OWF34985.1 - 1.5e-49 168.9 0.0 2.3e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Cation_efflux PF01545.21 OWF34987.1 - 2.4e-51 174.3 9.8 2.9e-51 174.0 9.8 1.1 1 0 0 1 1 1 1 Cation efflux family TIP120 PF08623.10 OWF34988.1 - 3e-65 219.1 1.4 3e-65 219.1 1.4 5.0 6 1 1 7 7 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OWF34988.1 - 9e-23 80.5 1.4 0.0028 18.0 0.0 8.8 6 2 1 8 8 8 6 HEAT repeats HEAT PF02985.22 OWF34988.1 - 4.6e-20 70.0 15.3 0.093 13.0 0.1 13.2 13 0 0 13 13 12 3 HEAT repeat HEAT_EZ PF13513.6 OWF34988.1 - 1.1e-17 64.1 6.8 0.002 18.6 0.0 10.8 10 1 1 11 11 10 3 HEAT-like repeat Adaptin_N PF01602.20 OWF34988.1 - 9.5e-10 37.6 20.5 0.095 11.2 0.3 7.1 3 3 1 6 6 6 4 Adaptin N terminal region Cnd1 PF12717.7 OWF34988.1 - 1.4e-08 34.9 20.9 0.011 15.8 1.8 8.3 6 3 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OWF34988.1 - 2.3e-07 30.6 5.6 0.11 12.1 0.0 6.2 5 1 2 7 7 6 2 CLASP N terminal DUF3385 PF11865.8 OWF34988.1 - 2.1e-06 27.7 10.8 0.0063 16.4 0.0 7.4 8 2 1 9 9 8 1 Domain of unknown function (DUF3385) UME PF08064.13 OWF34988.1 - 3.5e-06 26.9 6.8 0.55 10.2 0.0 7.5 6 1 3 9 9 8 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 OWF34988.1 - 3.4e-05 24.4 8.9 0.14 12.8 0.0 7.9 6 2 3 10 10 9 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 OWF34988.1 - 8.2e-05 22.5 2.2 28 4.9 0.0 7.0 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat Telomere_reg-2 PF10193.9 OWF34988.1 - 0.00019 21.8 9.5 3.9 8.0 0.2 6.6 6 0 0 6 6 6 2 Telomere length regulation protein NUC173 PF08161.12 OWF34988.1 - 0.00028 20.6 0.9 18 4.9 0.2 5.5 3 2 1 4 4 4 0 NUC173 domain TAF6_C PF07571.13 OWF34988.1 - 0.00042 20.6 1.4 3.9 7.9 0.0 5.3 2 1 2 5 5 4 1 TAF6 C-terminal HEAT repeat domain Tti2 PF10521.9 OWF34988.1 - 0.00091 18.9 1.9 1.5 8.3 0.0 4.9 5 1 0 5 5 5 1 Tti2 family RTP1_C1 PF10363.9 OWF34988.1 - 0.0025 18.0 8.7 3.9 7.7 0.2 6.8 7 1 1 8 8 8 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 OWF34988.1 - 0.012 15.4 6.0 0.57 9.9 0.8 5.1 2 2 2 4 4 4 0 rRNA processing/ribosome biogenesis VHS PF00790.19 OWF34988.1 - 0.015 15.1 6.1 0.25 11.2 0.6 4.3 4 0 0 4 4 4 0 VHS domain DNA_pol_phi PF04931.13 OWF34988.1 - 0.39 8.8 0.0 0.39 8.8 0.0 3.8 2 1 1 4 4 3 0 DNA polymerase phi RasGEF_N_2 PF14663.6 OWF34988.1 - 0.49 10.8 2.6 20 5.7 0.1 4.5 5 0 0 5 5 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sigma70_ner PF04546.13 OWF34988.1 - 1.1 9.1 5.7 1.5 8.6 1.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region V-ATPase_H_C PF11698.8 OWF34988.1 - 1.2 9.3 11.9 5 7.3 0.7 6.3 6 1 1 7 7 7 0 V-ATPase subunit H NOA36 PF06524.12 OWF34988.1 - 1.8 7.8 7.1 3.3 7.0 7.1 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1981 PF09324.10 OWF34988.1 - 4.7 7.1 5.3 19 5.2 0.0 4.7 8 0 0 8 8 5 0 Domain of unknown function (DUF1981) GCP_C_terminal PF04130.13 OWF34989.1 - 2.3e-41 142.2 8.4 2.3e-41 142.2 8.4 2.1 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OWF34989.1 - 9.4e-28 97.7 1.3 1.6e-27 97.0 0.2 2.0 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal zf-C2H2 PF00096.26 OWF34991.1 - 7.1e-31 104.9 63.2 5.5e-07 29.7 2.3 8.5 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF34991.1 - 9.4e-28 95.4 53.0 8.6e-08 32.3 3.4 8.3 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF34991.1 - 2.5e-27 93.2 55.6 0.00017 22.1 1.2 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger BTB PF00651.31 OWF34991.1 - 5.2e-25 87.8 0.1 1.1e-24 86.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.8 OWF34991.1 - 1.1e-17 63.8 37.2 0.0062 16.8 0.9 7.7 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF34991.1 - 6.8e-17 61.0 48.8 9.8e-05 22.3 1.3 8.2 8 1 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 OWF34991.1 - 8.7e-11 41.8 40.5 0.0035 17.7 1.3 7.7 7 0 0 7 7 7 4 Zinc-finger of C2H2 type BACK PF07707.15 OWF34991.1 - 1.4e-08 34.7 0.7 1.4e-08 34.7 0.7 1.8 2 0 0 2 2 1 1 BTB And C-terminal Kelch zf-Di19 PF05605.12 OWF34991.1 - 3.7e-05 23.9 36.0 0.026 14.8 2.1 4.9 3 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 OWF34991.1 - 3.8e-05 24.1 19.9 0.041 14.3 0.0 6.4 6 0 0 6 6 6 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_3rep PF18868.1 OWF34991.1 - 0.0001 22.9 18.5 0.86 10.3 0.0 6.1 3 1 1 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OWF34991.1 - 0.00014 22.2 37.2 0.51 10.7 1.0 7.7 3 1 5 8 8 8 3 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OWF34991.1 - 0.00014 21.5 31.6 0.034 13.9 0.6 6.5 6 0 0 6 6 6 2 zinc-finger C2H2-type GAGA PF09237.11 OWF34991.1 - 0.0062 16.3 3.9 0.28 11.0 0.2 3.5 2 1 1 3 3 3 1 GAGA factor zf-H2C2_5 PF13909.6 OWF34991.1 - 0.017 14.8 1.0 0.017 14.8 1.0 8.3 7 1 0 7 7 7 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 OWF34991.1 - 0.042 14.3 34.2 0.45 11.0 0.1 6.6 3 2 2 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger ADK_lid PF05191.14 OWF34991.1 - 0.049 13.6 18.3 6.9 6.7 0.7 5.1 4 1 0 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_9 PF16293.5 OWF34991.1 - 0.38 10.6 14.1 2.4 8.1 0.0 5.3 5 1 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Elf1 PF05129.13 OWF34991.1 - 1.4 9.0 18.2 1.3 9.2 1.5 3.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_9 PF14369.6 OWF34991.1 - 1.4 9.2 14.9 6.7 7.1 0.0 5.2 6 0 0 6 6 6 0 zinc-ribbon zf-BED PF02892.15 OWF34991.1 - 2.8 8.0 37.1 0.38 10.8 2.5 6.4 3 2 3 6 6 5 0 BED zinc finger zf-C2HC_2 PF13913.6 OWF34991.1 - 4.7 7.2 18.7 9.4 6.3 0.0 5.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type FYVE PF01363.21 OWF34991.1 - 9.9 6.4 25.7 0.3 11.3 3.1 4.1 2 1 1 4 4 4 0 FYVE zinc finger PsbN PF02468.15 OWF34992.1 - 0.99 9.3 3.2 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Fe-ADH PF00465.19 OWF34993.1 - 7.6e-103 344.1 0.0 8.9e-103 343.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OWF34993.1 - 3.2e-10 40.1 0.0 3.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Pyridoxal_deC PF00282.19 OWF34994.1 - 4.7e-16 58.5 0.0 1.2e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OWF34994.1 - 2.6e-10 39.8 0.0 5.1e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OWF34994.1 - 1.5e-05 24.4 0.0 0.00035 19.8 0.0 2.6 2 1 1 3 3 3 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OWF34994.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OWF34994.1 - 0.032 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OWF34994.1 - 0.16 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SOGA PF11365.8 OWF34995.1 - 1.3e-08 35.8 28.1 2.8e-08 34.8 14.5 13.6 7 2 5 13 13 13 3 Protein SOGA TSC22 PF01166.18 OWF34996.1 - 3.6e-05 24.0 23.4 0.0015 18.8 0.6 5.8 4 1 1 5 5 5 3 TSC-22/dip/bun family GAS PF13851.6 OWF34996.1 - 0.0018 17.7 14.2 0.0018 17.7 14.2 4.4 2 2 2 4 4 4 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 OWF34996.1 - 0.0026 18.0 11.1 0.0026 18.0 11.1 6.3 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 OWF34996.1 - 0.0092 16.2 13.5 0.0092 16.2 13.5 4.9 4 1 1 5 5 5 1 Fibrinogen alpha/beta chain family Shugoshin_N PF07558.11 OWF34996.1 - 0.017 15.0 5.2 1.1 9.2 0.0 4.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Pox_A_type_inc PF04508.12 OWF34996.1 - 0.028 14.3 0.1 0.028 14.3 0.1 5.7 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat WXG100 PF06013.12 OWF34996.1 - 0.084 13.1 0.3 0.084 13.1 0.3 4.3 4 1 1 5 5 5 0 Proteins of 100 residues with WXG YabA PF06156.13 OWF34996.1 - 0.55 10.9 50.3 0.088 13.5 3.6 6.0 2 1 4 6 6 6 0 Initiation control protein YabA SlyX PF04102.12 OWF34996.1 - 0.96 10.1 42.5 0.3 11.7 0.4 6.0 3 1 3 6 6 6 0 SlyX APG6_N PF17675.1 OWF34996.1 - 1.8 9.1 70.2 0.74 10.3 9.0 5.0 2 1 3 5 5 5 0 Apg6 coiled-coil region FXa_inhibition PF14670.6 OWF34997.1 - 8.8 6.7 19.1 8.9 6.7 5.5 3.7 3 1 0 3 3 3 0 Coagulation Factor Xa inhibitory site zf-C2H2 PF00096.26 OWF34998.1 - 1.6e-15 56.6 19.5 1.6e-05 25.1 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF34998.1 - 2.5e-11 43.4 17.1 0.00058 20.5 0.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF34998.1 - 5.2e-10 39.3 22.3 2.4e-05 24.6 0.2 3.9 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF34998.1 - 0.00012 22.3 10.2 0.085 13.2 0.9 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF34998.1 - 0.00024 21.0 6.2 0.003 17.5 1.0 3.8 5 0 0 5 5 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OWF34998.1 - 0.0029 17.7 6.5 0.038 14.1 1.2 2.5 2 0 0 2 2 2 1 Zinc ribbon domain C1_4 PF07975.12 OWF34998.1 - 0.0057 16.9 7.0 0.31 11.3 3.7 2.7 1 1 0 2 2 2 1 TFIIH C1-like domain XPA_N PF01286.18 OWF34998.1 - 0.012 15.6 7.3 0.85 9.7 0.7 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-AN1 PF01428.16 OWF34998.1 - 0.02 15.0 14.8 0.34 11.1 3.1 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger zf-C2HE PF16278.5 OWF34998.1 - 0.049 14.1 10.8 2.4 8.7 0.3 3.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 OWF34998.1 - 0.13 12.2 11.3 0.33 10.9 0.2 3.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FYVE PF01363.21 OWF34998.1 - 0.18 12.0 10.9 8.4 6.6 10.9 2.4 1 1 0 1 1 1 0 FYVE zinc finger zf-met PF12874.7 OWF34998.1 - 0.18 12.2 0.1 0.18 12.2 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF34998.1 - 0.2 12.0 6.8 0.51 10.7 1.9 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon CpXC PF14353.6 OWF34998.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.8 1 1 0 2 2 2 0 CpXC protein zf-UBR PF02207.20 OWF34998.1 - 0.26 11.5 5.6 0.59 10.3 5.6 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF3268 PF11672.8 OWF34998.1 - 0.29 11.5 4.2 0.098 13.0 1.0 1.8 1 1 1 2 2 2 0 zinc-finger-containing domain PyrI_C PF02748.15 OWF34998.1 - 0.38 10.7 5.8 0.95 9.4 0.0 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain LIM PF00412.22 OWF34998.1 - 0.54 10.5 9.1 10 6.4 4.2 2.5 1 1 0 2 2 2 0 LIM domain zf-Di19 PF05605.12 OWF34998.1 - 0.63 10.4 6.8 0.14 12.4 1.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 OWF34998.1 - 1.3 9.0 6.1 16 5.5 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 HNH PF01844.23 OWF34998.1 - 1.4 9.2 10.4 4.2 7.6 0.2 3.4 3 0 0 3 3 3 0 HNH endonuclease zf_UBZ PF18439.1 OWF34998.1 - 2.8 7.6 6.8 30 4.3 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 OWF34998.1 - 3.2 7.6 9.3 12 5.7 0.2 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-RING_5 PF14634.6 OWF34998.1 - 3.8 7.6 7.6 2.4 8.2 3.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-trcl PF13451.6 OWF34998.1 - 6.3 6.8 10.9 7.8 6.5 0.2 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain IBR PF01485.21 OWF34998.1 - 7.8 6.8 9.8 1e+02 3.3 9.9 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain ADH_N_2 PF16884.5 OWF34999.1 - 5.6e-25 87.3 0.0 9.2e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OWF34999.1 - 1.7e-14 53.9 0.0 2.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF34999.1 - 1.1e-06 29.8 0.0 2.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PAN_1 PF00024.26 OWF35000.1 - 3.7e-09 36.4 5.0 5.3e-09 35.9 5.0 1.2 1 0 0 1 1 1 1 PAN domain HycI PF01750.18 OWF35000.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase maturation protease Fibrinogen_C PF00147.18 OWF35001.1 - 1.1e-35 123.5 8.1 1.4e-35 123.1 8.1 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Sushi PF00084.20 OWF35001.1 - 1.3e-05 25.7 1.9 4.4e-05 24.0 1.9 2.0 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) EB PF01683.18 OWF35001.1 - 5e-05 23.5 6.9 0.00013 22.2 6.9 1.7 1 1 0 1 1 1 1 EB module cEGF PF12662.7 OWF35001.1 - 0.18 11.7 4.8 1 9.3 1.2 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like Thaumatin PF00314.17 OWF35002.1 - 1.6e-71 240.4 14.4 1.8e-71 240.2 14.4 1.0 1 0 0 1 1 1 1 Thaumatin family DUF3420 PF11900.8 OWF35003.1 - 0.021 15.0 4.8 35 4.7 0.0 6.6 9 0 0 9 9 9 0 Domain of unknown function (DUF3420) DUF5613 PF18467.1 OWF35003.1 - 0.24 11.8 37.5 0.99 9.9 5.8 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF5613) rpo132 PF12415.8 OWF35003.1 - 0.38 10.1 20.8 2.9 7.2 1.0 7.8 6 3 2 8 8 8 0 Poxvirus DNA dependent RNA polymerase Fer4_13 PF13370.6 OWF35003.1 - 8.3 7.0 10.9 1.2e+02 3.3 0.1 5.1 3 2 2 5 5 5 0 4Fe-4S single cluster domain of Ferredoxin I Tetraspanin PF00335.20 OWF35004.1 - 5e-18 65.6 21.6 6.6e-15 55.4 14.4 2.1 1 1 1 2 2 2 2 Tetraspanin family Yip1 PF04893.17 OWF35004.1 - 0.0091 15.7 7.7 0.016 14.9 7.7 1.4 1 0 0 1 1 1 1 Yip1 domain Tetraspanin PF00335.20 OWF35005.1 - 1.5e-14 54.3 5.4 2.1e-14 53.8 5.4 1.2 1 0 0 1 1 1 1 Tetraspanin family PQ-loop PF04193.14 OWF35005.1 - 1.1 9.1 7.1 0.8 9.5 0.2 3.6 3 1 1 4 4 4 0 PQ loop repeat Claudin_2 PF13903.6 OWF35005.1 - 1.4 8.7 11.6 39 3.9 0.0 3.3 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction RhoGAP PF00620.27 OWF35006.1 - 1.4e-15 57.4 0.0 4.2e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain EF-hand_9 PF14658.6 OWF35006.1 - 0.06 13.7 0.8 1.9 8.9 0.5 3.0 2 0 0 2 2 2 0 EF-hand domain ddrB-ParB PF18763.1 OWF35006.1 - 0.066 13.3 0.5 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 ddrB-like ParB superfamily domain fn3 PF00041.21 OWF35007.1 - 2.8e-09 37.2 0.4 2.8e-09 37.2 0.4 2.6 3 0 0 3 3 3 1 Fibronectin type III domain Ig_3 PF13927.6 OWF35007.1 - 6.2e-09 36.3 2.5 6.2e-09 36.3 2.5 2.4 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 OWF35007.1 - 2.8e-08 34.0 2.4 2.8e-08 34.0 2.4 2.2 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF35007.1 - 7.1e-08 32.4 2.5 9.1e-07 28.9 0.4 3.1 2 1 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 OWF35007.1 - 0.0023 18.1 2.0 0.23 11.6 0.1 2.9 2 1 1 3 3 3 1 Immunoglobulin V-set domain ig PF00047.25 OWF35007.1 - 0.0081 16.3 2.8 0.27 11.4 2.8 2.6 1 1 0 1 1 1 1 Immunoglobulin domain GPI-anchored PF10342.9 OWF35007.1 - 0.0082 16.9 1.9 0.0082 16.9 1.9 2.9 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pur_ac_phosph_N PF16656.5 OWF35007.1 - 0.011 16.3 1.5 0.011 16.3 1.5 2.9 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.5 OWF35007.1 - 0.046 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain DUF3796 PF12676.7 OWF35007.1 - 0.05 14.1 0.5 0.099 13.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF2369 PF10179.9 OWF35007.1 - 0.059 13.8 0.5 0.27 11.7 0.1 2.3 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2369) Ig_C17orf99 PF17736.1 OWF35007.1 - 0.095 12.8 1.5 0.79 9.8 0.4 2.7 2 1 0 2 2 2 0 C17orf99 Ig domain Claudin_3 PF06653.11 OWF35008.1 - 0.58 10.1 10.9 1.2 9.0 10.8 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Glyco_transf_54 PF04666.13 OWF35009.1 - 2e-70 237.0 1.6 3e-70 236.4 1.6 1.3 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Apc13p PF05839.11 OWF35010.1 - 1.6e-12 47.5 2.6 4.3e-12 46.1 2.6 1.6 1 1 0 1 1 1 1 Apc13p protein Lactamase_B PF00753.27 OWF35011.1 - 3.3e-16 59.9 1.2 1.2e-14 54.7 1.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OWF35011.1 - 0.0002 21.0 0.2 0.00046 19.8 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ADH_N PF08240.12 OWF35012.1 - 7.8e-28 96.5 1.7 1.6e-27 95.6 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OWF35012.1 - 2.6e-20 72.7 0.1 3.9e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OWF35012.1 - 6.1e-05 22.6 0.7 0.00027 20.5 0.7 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OWF35012.1 - 0.00054 19.3 0.1 0.00087 18.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 OWF35012.1 - 0.031 14.3 0.3 0.06 13.4 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OWF35012.1 - 0.05 13.2 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GvpK PF05121.12 OWF35013.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle protein K 7tm_1 PF00001.21 OWF35014.1 - 1e-20 74.2 20.7 1.3e-20 73.9 20.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CD20 PF04103.15 OWF35015.1 - 5.3e-09 36.4 10.1 1.1e-08 35.3 10.0 1.7 1 1 0 1 1 1 1 CD20-like family ApeC PF16977.5 OWF35016.1 - 7.8e-60 202.3 6.9 7.8e-60 202.3 6.9 1.5 2 0 0 2 2 2 1 C-terminal domain of apextrin MACPF PF01823.19 OWF35016.1 - 4.2e-11 43.3 0.4 7.9e-11 42.4 0.4 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Prominin PF05478.11 OWF35016.1 - 0.13 10.2 0.2 0.17 9.8 0.2 1.1 1 0 0 1 1 1 0 Prominin zf-B_box PF00643.24 OWF35017.1 - 0.0046 17.1 11.5 0.012 15.7 11.5 1.8 1 0 0 1 1 1 1 B-box zinc finger OTU PF02338.19 OWF35017.1 - 0.034 14.7 0.2 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 OTU-like cysteine protease zf-UBR PF02207.20 OWF35017.1 - 0.078 13.2 7.2 0.25 11.5 7.2 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) v110 PF01639.17 OWF35017.1 - 2 8.4 7.2 5.8 6.8 7.2 1.8 1 0 0 1 1 1 0 Viral family 110 zf-C2H2 PF00096.26 OWF35018.1 - 5.3e-28 95.9 54.3 2.8e-06 27.5 2.2 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF35018.1 - 5.8e-24 83.4 48.7 0.00038 20.8 3.7 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF35018.1 - 1.7e-19 68.8 47.5 0.0028 18.3 1.5 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF35018.1 - 7.4e-09 35.4 44.2 0.0072 16.3 4.3 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF35018.1 - 2.7e-07 30.7 35.4 0.26 11.6 1.7 6.7 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 OWF35018.1 - 0.011 16.5 19.6 0.49 11.2 1.4 3.6 2 1 1 3 3 3 0 zinc-ribbon family zf-met PF12874.7 OWF35018.1 - 0.021 15.2 32.5 0.29 11.6 1.0 6.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Rep_fac-A_C PF08646.10 OWF35018.1 - 0.028 14.2 11.0 2.9 7.6 1.2 3.6 2 1 0 3 3 3 0 Replication factor-A C terminal domain CpXC PF14353.6 OWF35018.1 - 0.039 14.0 0.3 0.039 14.0 0.3 4.5 1 1 3 5 5 5 0 CpXC protein zf-C2H2_11 PF16622.5 OWF35018.1 - 0.097 12.4 0.2 0.097 12.4 0.2 5.1 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_UBZ PF18439.1 OWF35018.1 - 0.1 12.2 20.1 0.25 10.9 0.1 6.0 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger RAG1_imp_bd PF12560.8 OWF35018.1 - 0.11 12.0 17.6 1.1 8.7 3.1 3.5 1 1 2 3 3 3 0 RAG1 importin binding OrfB_Zn_ribbon PF07282.11 OWF35018.1 - 0.12 12.3 0.1 0.12 12.3 0.1 4.8 2 1 3 5 5 5 0 Putative transposase DNA-binding domain FYVE PF01363.21 OWF35018.1 - 0.13 12.4 30.9 0.14 12.3 8.1 3.8 1 1 1 2 2 1 0 FYVE zinc finger GAGA PF09237.11 OWF35018.1 - 0.14 12.0 12.1 5.9 6.8 0.1 4.6 2 2 3 5 5 5 0 GAGA factor Zn-ribbon_8 PF09723.10 OWF35018.1 - 0.15 12.2 23.1 0.42 10.8 0.8 4.6 2 1 3 5 5 5 0 Zinc ribbon domain zf-Di19 PF05605.12 OWF35018.1 - 0.19 12.0 30.5 0.052 13.9 6.3 4.1 2 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 OWF35018.1 - 0.42 10.8 31.9 0.56 10.4 1.9 6.2 5 1 1 6 6 6 0 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 OWF35018.1 - 0.57 10.9 25.7 0.69 10.6 0.8 5.0 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-Sec23_Sec24 PF04810.15 OWF35018.1 - 1.3 9.1 24.4 0.86 9.7 1.4 4.9 3 2 1 4 4 4 0 Sec23/Sec24 zinc finger zf-CCHC_2 PF13696.6 OWF35018.1 - 2 8.3 19.4 6.2 6.7 0.3 4.6 4 0 0 4 4 4 0 Zinc knuckle zf-C2H2_9 PF16293.5 OWF35018.1 - 2.8 7.8 11.0 39 4.2 0.5 4.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) TF_Zn_Ribbon PF08271.12 OWF35018.1 - 6.1 6.5 11.6 7.8 6.1 0.0 4.9 4 1 1 5 5 5 0 TFIIB zinc-binding Zf_RING PF16744.5 OWF35018.1 - 7.7 6.7 23.8 0.43 10.7 0.6 5.5 1 1 5 6 6 6 0 KIAA1045 RING finger DUF2197 PF09963.9 OWF35018.1 - 9.3 6.6 13.6 0.27 11.5 0.2 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2197) Usp PF00582.26 OWF35019.1 - 7.8e-25 88.0 0.1 9.3e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 OWF35020.1 - 2.7e-30 105.7 0.0 3.4e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family TfuA PF07812.12 OWF35020.1 - 0.017 14.9 0.2 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 TfuA-like protein Usp PF00582.26 OWF35021.1 - 9.9e-29 100.7 0.1 1.5e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family EF-hand_1 PF00036.32 OWF35022.1 - 2.5e-09 36.0 0.0 1.6e-05 24.1 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OWF35022.1 - 2e-08 33.4 0.1 5.2e-05 22.6 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF35022.1 - 8.3e-07 28.4 0.1 0.0005 19.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF35022.1 - 2.4e-06 27.9 0.1 1.6e-05 25.2 0.1 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF35022.1 - 0.00012 21.9 0.0 0.026 14.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair FG-GAP PF01839.23 OWF35022.1 - 0.55 10.4 4.1 6.8 6.9 0.3 2.5 2 0 0 2 2 2 0 FG-GAP repeat F-box-like PF12937.7 OWF35023.1 - 3.8e-09 36.3 1.0 3.8e-09 36.3 1.0 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 OWF35023.1 - 0.052 13.5 2.1 0.07 13.0 0.3 2.3 2 0 0 2 2 2 0 F-box domain SPOC PF07744.13 OWF35024.1 - 2.4e-33 115.2 0.0 5e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 OWF35024.1 - 6e-32 109.3 0.0 4.5e-14 52.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF35024.1 - 5e-06 26.5 0.0 0.11 12.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OWF35024.1 - 2.8e-05 24.0 0.3 1.6 8.8 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OWF35024.1 - 0.013 15.5 0.0 3.6 7.7 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif Pkinase PF00069.25 OWF35025.1 - 9.6e-66 221.8 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35025.1 - 1.3e-30 106.5 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF35025.1 - 1.1e-06 28.2 0.1 2.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF35025.1 - 6.6e-05 22.4 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OWF35025.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase VF530 PF09905.9 OWF35025.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA-binding protein VF530 tRNA-synt_1 PF00133.22 OWF35026.1 - 7e-234 777.6 0.7 7e-234 777.6 0.7 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OWF35026.1 - 2.2e-24 86.1 0.0 7.7e-24 84.4 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OWF35026.1 - 5.4e-16 58.3 1.9 1.1e-05 24.4 0.3 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OWF35026.1 - 0.002 17.5 0.0 0.042 13.2 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Isochorismatase PF00857.20 OWF35027.1 - 5.8e-09 36.4 0.1 9.9e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Isochorismatase family EMC3_TMCO1 PF01956.16 OWF35028.1 - 1e-37 129.5 0.5 1e-37 129.5 0.5 1.7 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Prefoldin PF02996.17 OWF35029.1 - 2.3e-19 69.5 1.6 3e-19 69.1 1.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OWF35029.1 - 0.013 15.4 3.4 0.35 10.8 0.0 2.6 2 1 0 2 2 2 0 Prefoldin subunit YtzH PF14165.6 OWF35029.1 - 0.074 13.5 0.5 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 YtzH-like protein LamB_YcsF PF03746.16 OWF35029.1 - 0.1 12.3 0.9 1.8 8.2 0.1 2.0 2 0 0 2 2 2 0 LamB/YcsF family NPV_P10 PF05531.12 OWF35029.1 - 2.6 8.6 6.2 10 6.6 0.2 2.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 OWF35029.1 - 3.3 6.7 4.8 15 4.6 4.8 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4097 PF13349.6 OWF35030.1 - 4.5e-09 36.0 15.1 6.6e-09 35.5 15.1 1.2 1 0 0 1 1 1 1 Putative adhesin Caveolin PF01146.17 OWF35031.1 - 2.9e-40 137.3 0.0 3.2e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF35032.1 - 1.1e-36 125.8 0.1 1.2e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF35033.1 - 6.3e-38 129.7 0.2 6.8e-38 129.6 0.2 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF35034.1 - 1.2e-40 138.5 0.1 1.3e-40 138.4 0.1 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF35035.1 - 3.3e-40 137.1 0.3 3.9e-40 136.9 0.3 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF35036.1 - 6.9e-50 168.4 0.4 4.4e-38 130.2 0.1 2.1 2 0 0 2 2 2 2 Caveolin FUSC_2 PF13515.6 OWF35036.1 - 0.06 13.5 1.7 0.096 12.8 1.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Caveolin PF01146.17 OWF35037.1 - 4.5e-40 136.7 0.3 4.8e-40 136.6 0.3 1.0 1 0 0 1 1 1 1 Caveolin FUSC_2 PF13515.6 OWF35037.1 - 0.023 14.8 0.8 0.034 14.3 0.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like SpoVAB PF13782.6 OWF35037.1 - 0.16 12.3 3.1 0.57 10.5 2.6 1.8 1 1 1 2 2 2 0 Stage V sporulation protein AB Caveolin PF01146.17 OWF35038.1 - 8.7e-39 132.5 0.3 9.5e-39 132.4 0.3 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF35039.1 - 1.2e-37 128.8 0.2 1.3e-37 128.7 0.2 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF35040.1 - 2.6e-37 127.8 1.6 2.9e-37 127.6 1.6 1.0 1 0 0 1 1 1 1 Caveolin ApeC PF16977.5 OWF35041.1 - 1.7e-50 171.9 0.3 4e-50 170.6 0.3 1.7 1 0 0 1 1 1 1 C-terminal domain of apextrin Ldl_recept_a PF00057.18 OWF35041.1 - 3.7e-39 132.6 99.7 3.4e-10 40.0 7.1 7.6 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 OWF35041.1 - 2.3e-30 104.2 19.3 5.9e-13 48.4 8.2 4.6 2 1 2 4 4 4 3 Leucine rich repeat 7tm_1 PF00001.21 OWF35041.1 - 8.8e-28 97.3 11.1 1.4e-27 96.7 11.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CUB PF00431.20 OWF35041.1 - 1.3e-13 51.3 0.0 1.7e-06 28.3 0.0 2.8 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.25 OWF35041.1 - 3.1e-12 46.7 0.0 5.6e-09 36.2 0.0 2.7 2 0 0 2 2 2 2 F5/8 type C domain LRR_4 PF12799.7 OWF35041.1 - 1.6e-10 41.0 15.3 7.5e-05 23.0 0.8 5.0 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF35041.1 - 0.00017 21.1 5.5 0.042 13.4 0.5 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OWF35041.1 - 0.0018 18.5 8.2 5.9 7.8 0.3 6.3 4 1 0 4 4 4 1 Leucine Rich Repeat Serpentine_r_xa PF03383.15 OWF35041.1 - 0.006 16.6 4.4 0.012 15.6 4.4 1.5 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa GN3L_Grn1 PF08701.11 OWF35042.1 - 7.2e-20 70.9 28.0 7.2e-20 70.9 28.0 3.6 2 1 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OWF35042.1 - 1.2e-15 57.5 0.1 4e-12 46.2 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF35042.1 - 9e-10 38.3 0.2 3.2e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF35042.1 - 3.3e-05 23.8 0.1 0.03 14.2 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase YL1 PF05764.13 OWF35042.1 - 2.6 8.1 56.2 0.26 11.4 21.2 2.3 2 0 0 2 2 2 0 YL1 nuclear protein TRAP-delta PF05404.12 OWF35043.1 - 1.4e-63 213.3 0.0 1.7e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) LRR_6 PF13516.6 OWF35044.1 - 4.5e-22 76.2 30.0 0.00016 21.5 0.0 9.3 9 0 0 9 9 9 7 Leucine Rich repeat CARD PF00619.21 OWF35044.1 - 0.004 17.1 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Caspase recruitment domain LRR_4 PF12799.7 OWF35044.1 - 0.46 11.0 22.7 11 6.5 0.3 6.5 3 2 4 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF35044.1 - 5.4 8.0 13.4 27 5.8 0.0 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat GSAP-16 PF14959.6 OWF35045.1 - 2.8e-25 88.3 0.0 7.2e-25 87.0 0.0 1.8 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term DUF2857 PF11198.8 OWF35045.1 - 0.002 17.9 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2857) RNase_P_Rpp14 PF01900.19 OWF35046.1 - 4.5e-11 42.9 0.0 5.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family AIG1 PF04548.16 OWF35048.1 - 7.2e-66 221.5 0.0 7.2e-66 221.5 0.0 1.8 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF35048.1 - 5.3e-07 29.7 0.0 1.6e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-RanBP PF00641.18 OWF35048.1 - 9.3e-05 21.7 4.4 9.3e-05 21.7 4.4 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others FeoB_N PF02421.18 OWF35048.1 - 0.00014 21.4 0.0 0.00035 20.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF3584 PF12128.8 OWF35048.1 - 0.017 12.7 24.8 0.023 12.3 24.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 OWF35048.1 - 0.71 9.9 14.5 1.6 8.7 10.9 2.7 2 1 1 3 3 3 0 Laminin Domain II ABC_tran PF00005.27 OWF35048.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.0 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 OWF35048.1 - 6.7 7.1 6.1 0.59 10.5 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain DZR PF12773.7 OWF35048.1 - 7.8 6.6 13.3 27 4.9 11.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon ERM PF00769.19 OWF35048.1 - 8.2 6.2 42.5 0.25 11.2 20.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Usp PF00582.26 OWF35049.1 - 2e-25 90.0 0.0 5.1e-25 88.6 0.0 1.6 1 1 0 1 1 1 1 Universal stress protein family ThiF PF00899.21 OWF35050.1 - 6.7e-111 369.5 0.2 1.4e-72 244.0 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OWF35050.1 - 2.5e-91 306.1 0.2 4.4e-91 305.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 OWF35050.1 - 5.1e-38 129.7 0.1 1.4e-37 128.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 OWF35050.1 - 2.2e-33 114.3 0.1 5.7e-33 112.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 OWF35050.1 - 1e-25 89.7 0.1 3.1e-25 88.1 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 OWF35050.1 - 0.0038 17.7 0.1 0.15 12.5 0.0 3.0 3 0 0 3 3 3 1 Putative NAD(P)-binding Glyco_transf_11 PF01531.16 OWF35051.1 - 7.8e-14 51.6 0.1 8.4e-14 51.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Ank_2 PF12796.7 OWF35053.1 - 3.6e-48 162.1 0.2 4.8e-12 46.3 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF35053.1 - 1.5e-28 98.4 2.9 8.9e-08 32.3 0.1 6.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF35053.1 - 5.4e-27 93.8 1.8 3.2e-10 40.3 0.0 5.1 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF35053.1 - 1.4e-24 85.4 7.3 1.1e-05 25.7 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OWF35053.1 - 1.4e-24 83.4 5.8 0.00017 21.7 0.0 7.6 8 0 0 8 8 7 5 Ankyrin repeat Death PF00531.22 OWF35053.1 - 0.0017 18.5 0.6 0.0065 16.6 0.1 2.2 1 1 1 2 2 2 1 Death domain IstB_IS21 PF01695.17 OWF35053.1 - 0.0066 16.2 0.0 0.13 12.0 0.0 2.4 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.6 OWF35053.1 - 0.011 16.0 0.0 0.058 13.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OWF35053.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PBP_GOBP PF01395.22 OWF35053.1 - 0.031 14.4 3.0 5.8 7.1 0.0 3.6 3 0 0 3 3 3 0 PBP/GOBP family AAA_11 PF13086.6 OWF35053.1 - 0.081 12.7 0.1 0.25 11.1 0.1 1.7 1 1 1 2 2 2 0 AAA domain Neur_chan_memb PF02932.16 OWF35054.1 - 3.6e-14 53.4 7.0 4.8e-14 53.0 7.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF35054.1 - 0.0025 17.3 0.1 0.0033 16.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2070 PF09843.9 OWF35054.1 - 0.02 13.2 2.6 0.023 13.0 2.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Herpes_LMP1 PF05297.11 OWF35054.1 - 0.97 8.6 2.7 1.1 8.3 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PKD_channel PF08016.12 OWF35055.1 - 1.2e-07 30.8 15.6 1.7e-07 30.3 15.6 1.4 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 OWF35055.1 - 4.1e-06 26.2 25.7 1.1e-05 24.8 25.7 1.7 1 1 0 1 1 1 1 Ion transport protein TMEM52 PF14979.6 OWF35056.1 - 0.12 12.3 0.4 0.28 11.1 0.4 1.6 1 0 0 1 1 1 0 Transmembrane 52 PX PF00787.24 OWF35057.1 - 7.8e-18 64.5 0.3 2.7e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 PX domain WH2 PF02205.20 OWF35057.1 - 1.2e-05 24.9 0.9 1.2e-05 24.9 0.9 2.4 2 0 0 2 2 2 1 WH2 motif MNR PF15718.5 OWF35057.1 - 0.0002 19.7 1.7 0.00027 19.3 1.7 1.1 1 0 0 1 1 1 1 Protein moonraker Pkinase PF00069.25 OWF35057.1 - 0.0037 16.7 0.0 0.068 12.5 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35057.1 - 0.0047 16.3 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RGCC PF15151.6 OWF35057.1 - 0.0074 16.5 1.1 0.012 15.8 1.1 1.3 1 0 0 1 1 1 1 Response gene to complement 32 protein family DPM2 PF07297.12 OWF35057.1 - 0.09 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PHC2_SAM_assoc PF16616.5 OWF35057.1 - 0.22 12.3 7.1 0.44 11.4 7.1 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF755 PF05501.11 OWF35057.1 - 0.75 10.1 17.3 1.3 9.3 17.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FAP PF07174.11 OWF35057.1 - 6.6 6.1 26.6 10 5.4 26.6 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Totivirus_coat PF05518.11 OWF35057.1 - 7.2 4.5 14.7 10 4.0 14.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein DSPc PF00782.20 OWF35058.1 - 5e-43 146.1 0.0 8.3e-43 145.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 OWF35058.1 - 2.7e-11 43.9 0.0 6.7e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 OWF35058.1 - 0.00031 20.4 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 OWF35058.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 OWF35058.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Pentapeptide_2 PF01469.18 OWF35060.1 - 0.011 15.5 5.6 0.011 15.5 5.6 4.1 2 2 2 4 4 4 0 Pentapeptide repeats (8 copies) V-set PF07686.17 OWF35063.1 - 0.025 14.7 0.1 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain EphA2_TM PF14575.6 OWF35063.1 - 0.033 15.1 0.0 0.28 12.1 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.6 OWF35063.1 - 0.042 14.4 0.1 0.42 11.2 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain TFIIIC_sub6 PF10419.9 OWF35064.1 - 6.6e-18 64.4 0.1 1.6e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Kelch_1 PF01344.25 OWF35065.1 - 4.2e-33 112.7 18.3 4.4e-11 42.2 0.5 7.3 7 1 0 7 7 7 5 Kelch motif BTB PF00651.31 OWF35065.1 - 4e-29 101.1 0.0 6.8e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 OWF35065.1 - 3.3e-26 90.7 5.4 2.6e-06 27.5 0.0 6.6 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 OWF35065.1 - 1e-22 80.2 2.6 1e-22 80.1 1.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 OWF35065.1 - 5.2e-16 58.5 7.5 0.012 15.9 0.1 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF35065.1 - 2.5e-15 56.2 3.3 0.0035 17.3 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF35065.1 - 1.9e-14 53.0 2.9 0.023 14.7 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 OWF35065.1 - 1.9e-12 46.9 5.4 0.02 14.9 0.1 5.2 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 OWF35065.1 - 0.0071 16.5 0.1 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) 4HPAD_g_N PF18671.1 OWF35066.1 - 1.5e-05 24.6 23.6 1.5e+02 2.2 0.0 13.1 17 0 0 17 17 17 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal zf_C2H2_6 PF18450.1 OWF35066.1 - 0.0012 18.6 44.4 1.3e+02 2.4 0.1 15.9 17 0 0 17 17 17 0 Zinc Finger domain DUF2670 PF10875.8 OWF35066.1 - 5 7.2 33.7 57 3.8 0.6 8.4 1 1 10 12 12 12 0 Protein of unknown function (DUF2670) Cadherin-like PF12733.7 OWF35067.1 - 5.4e-08 33.2 0.1 1.2e-07 32.2 0.1 1.6 1 0 0 1 1 1 1 Cadherin-like beta sandwich domain Terminase_GpA PF05876.12 OWF35067.1 - 0.039 12.5 1.5 0.062 11.9 1.5 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Pkinase_Tyr PF07714.17 OWF35068.1 - 6.5e-61 205.9 0.0 1.2e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF35068.1 - 1.5e-57 195.0 0.0 2.7e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 OWF35068.1 - 2.4e-16 59.6 0.0 4.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 OWF35068.1 - 2.1e-09 37.1 6.3 4.2e-09 36.1 6.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 OWF35068.1 - 2.2e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF35068.1 - 0.00076 18.4 0.0 0.0022 16.9 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase C1_2 PF03107.16 OWF35068.1 - 0.0034 17.7 3.7 0.0076 16.5 3.7 1.6 1 0 0 1 1 1 1 C1 domain zf-RING-like PF08746.11 OWF35068.1 - 0.0065 16.8 4.5 0.014 15.7 4.5 1.5 1 0 0 1 1 1 1 RING-like domain TUG-UBL1 PF11470.8 OWF35068.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain Fmp27_WPPW PF10359.9 OWF35068.1 - 0.061 12.2 1.8 0.067 12.0 0.6 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain GCIP PF13324.6 OWF35068.1 - 0.065 12.8 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting APH PF01636.23 OWF35068.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PHD PF00628.29 OWF35068.1 - 0.13 12.2 5.1 0.5 10.3 5.2 2.0 1 1 0 1 1 1 0 PHD-finger DUF1258 PF06869.12 OWF35068.1 - 0.19 11.2 1.8 0.3 10.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) PHD_2 PF13831.6 OWF35068.1 - 1.2 8.7 4.6 0.32 10.6 1.2 1.8 2 0 0 2 2 2 0 PHD-finger P4Ha_N PF08336.11 OWF35069.1 - 8.4e-18 64.7 0.3 3e-17 62.9 0.0 2.1 3 0 0 3 3 3 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 OWF35069.1 - 2.5e-06 28.3 0.2 7.7e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PhaP_Bmeg PF09602.10 OWF35069.1 - 0.0021 18.0 0.7 1.4 8.8 0.0 3.4 3 1 1 4 4 4 2 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SRP14 PF02290.15 OWF35069.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle 14kD protein DUF4607 PF15380.6 OWF35070.1 - 0.0038 16.8 2.3 14 5.1 0.1 3.8 1 1 7 8 8 8 1 Domain of unknown function (DUF4607) Keratin_B2 PF01500.17 OWF35070.1 - 0.092 12.7 7.9 14 5.6 1.0 2.8 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein LamB PF02264.15 OWF35070.1 - 0.65 9.8 9.3 1.1e+02 2.5 0.1 5.7 1 1 3 4 4 4 0 LamB porin UPF0697 PF15117.6 OWF35070.1 - 0.77 9.9 6.8 8.2 6.6 1.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0697 Fer2_4 PF13510.6 OWF35070.1 - 2.7 8.1 7.6 58 3.8 0.8 3.2 1 1 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain NS3_envE PF02723.14 OWF35070.1 - 3.4 7.8 19.1 19 5.4 1.3 4.6 1 1 5 6 6 6 0 Non-structural protein NS3/Small envelope protein E Homeobox_KN PF05920.11 OWF35071.1 - 2.3e-16 59.4 0.3 5.9e-16 58.1 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF35071.1 - 1.3e-07 31.3 1.2 2.7e-07 30.3 1.2 1.6 1 0 0 1 1 1 1 Homeodomain Carb_anhydrase PF00194.21 OWF35072.1 - 4.4e-70 236.1 0.0 5.9e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF4091 PF13320.6 OWF35072.1 - 0.12 12.6 0.1 0.39 10.9 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4091) Homeobox_KN PF05920.11 OWF35073.1 - 2.6e-16 59.2 0.3 6.4e-16 58.0 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF35073.1 - 2.2e-07 30.6 1.8 3.5e-07 30.0 1.8 1.3 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 OWF35073.1 - 0.13 12.8 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 SQHop_cyclase_C PF13243.6 OWF35074.1 - 1.7 7.7 4.3 7.4 5.6 0.1 3.1 1 1 3 4 4 4 0 Squalene-hopene cyclase C-terminal domain Phage_pRha PF09669.10 OWF35075.1 - 0.028 15.0 0.4 3.9 8.1 0.4 2.9 1 1 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) LBR_tudor PF09465.10 OWF35075.1 - 0.028 14.2 1.8 16 5.4 0.1 3.1 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain DUF1073 PF06381.11 OWF35075.1 - 0.41 9.4 1.1 1.7 7.3 0.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1073) LBR_tudor PF09465.10 OWF35076.1 - 0.0088 15.8 7.0 16 5.4 0.1 4.1 4 0 0 4 4 4 3 Lamin-B receptor of TUDOR domain Phage_pRha PF09669.10 OWF35076.1 - 0.18 12.4 0.2 3 8.5 0.0 2.5 1 1 2 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) Metallophos PF00149.28 OWF35077.1 - 6.1e-12 46.5 1.6 1.2e-11 45.5 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF35077.1 - 3.8e-05 23.9 0.3 6.3e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SfLAP PF11139.8 OWF35077.1 - 0.0025 17.3 0.2 0.1 12.0 0.1 2.1 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein Metallophos_3 PF14582.6 OWF35077.1 - 0.061 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Wzy_C PF04932.15 OWF35077.1 - 0.14 11.8 7.2 1.2 8.7 4.6 2.3 1 1 1 2 2 2 0 O-Antigen ligase DUF420 PF04238.12 OWF35077.1 - 2.6 8.3 16.1 0.71 10.2 10.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) COX15-CtaA PF02628.15 OWF35077.1 - 4.1 6.4 9.2 0.3 10.1 0.6 2.2 2 1 0 2 2 2 0 Cytochrome oxidase assembly protein WD40 PF00400.32 OWF35078.1 - 6.4e-21 74.3 16.9 0.00016 22.4 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35078.1 - 4.4e-08 33.3 0.0 0.0043 17.3 0.0 5.2 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF35078.1 - 0.0046 16.0 1.0 1.3 7.9 0.0 3.3 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF917 PF06032.12 OWF35079.1 - 4.1e-96 321.9 0.0 2.9e-95 319.1 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 OWF35079.1 - 2.2e-30 105.9 7.4 7.2e-28 97.7 0.6 3.4 2 1 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OWF35079.1 - 1.5e-27 96.5 8.7 1.9e-26 92.9 0.5 3.2 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 OWF35079.1 - 4.5e-05 22.2 5.8 0.02 13.5 0.5 3.0 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 OWF35079.1 - 0.00023 20.7 2.7 0.22 11.0 0.2 3.3 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family PCP PF02429.15 OWF35079.1 - 0.0012 19.2 0.1 0.0039 17.5 0.1 1.8 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein FtsA PF14450.6 OWF35079.1 - 0.0064 16.9 9.4 0.19 12.2 2.2 3.7 2 2 0 3 3 3 2 Cell division protein FtsA Aldolase PF01081.19 OWF35079.1 - 0.0086 15.5 0.5 3.7 6.9 0.0 2.7 2 0 0 2 2 2 2 KDPG and KHG aldolase StbA PF06406.11 OWF35079.1 - 2.6 7.2 4.8 3.9 6.6 0.0 2.8 3 1 0 4 4 4 0 StbA protein EF-hand_1 PF00036.32 OWF35080.1 - 6.7e-25 84.7 9.0 3.9e-06 26.0 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF35080.1 - 2.9e-22 77.1 3.8 3.9e-06 26.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF35080.1 - 1.6e-21 76.5 2.9 6.7e-10 39.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF35080.1 - 5.5e-19 66.4 9.4 3.7e-06 26.4 0.2 4.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 OWF35080.1 - 4.6e-13 48.8 12.2 4e-05 23.4 0.4 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF35080.1 - 1.1e-06 28.8 0.1 0.0037 17.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF35080.1 - 3.3e-05 23.8 0.2 0.015 15.2 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF35080.1 - 0.0002 21.4 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 2 Caleosin related protein SPARC_Ca_bdg PF10591.9 OWF35080.1 - 0.00027 21.2 0.0 0.034 14.5 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF3741 PF12552.8 OWF35080.1 - 0.86 9.6 2.9 3.3 7.7 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3741) Beta-lactamase PF00144.24 OWF35081.1 - 5.7e-54 183.6 0.0 7.2e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase AA_permease_2 PF13520.6 OWF35082.1 - 8.6e-65 219.2 39.9 1.1e-64 218.9 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF35082.1 - 1e-27 96.9 36.6 1.5e-27 96.4 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0220 PF05255.11 OWF35082.1 - 0.036 13.6 0.1 0.036 13.6 0.1 3.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0220) DUF2207 PF09972.9 OWF35082.1 - 0.87 8.3 0.0 0.87 8.3 0.0 3.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.6 OWF35083.1 - 3.7e-66 223.7 38.7 4.5e-66 223.4 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF35083.1 - 1.2e-29 103.2 37.6 3.2e-29 101.9 37.6 1.6 1 1 0 1 1 1 1 Amino acid permease TORC_N PF12884.7 OWF35084.1 - 0.049 14.4 14.5 0.052 14.3 1.6 3.4 2 1 0 2 2 2 0 Transducer of regulated CREB activity, N terminus TSC22 PF01166.18 OWF35084.1 - 0.051 13.9 3.9 4.5 7.7 0.1 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family CLZ PF16526.5 OWF35084.1 - 0.88 10.0 13.8 0.87 10.0 1.6 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HisKA PF00512.25 OWF35084.1 - 2.2 8.4 6.0 18 5.5 0.3 2.7 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain FUSC PF04632.12 OWF35084.1 - 7.1 5.0 8.8 13 4.1 8.5 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF745 PF05335.13 OWF35085.1 - 1.2e-14 54.4 0.0 0.072 12.8 0.0 4.9 1 1 2 4 4 4 4 Protein of unknown function (DUF745) DUF357 PF04010.13 OWF35085.1 - 6.6e-14 51.7 61.8 6.1 7.0 0.1 16.8 1 1 14 15 15 15 15 Protein of unknown function (DUF357) Bromodomain PF00439.25 OWF35085.1 - 0.00039 20.4 109.3 8.7 6.5 3.0 12.8 1 1 15 17 17 17 17 Bromodomain QRPTase_N PF02749.16 OWF35086.1 - 0.009 16.0 0.3 24 5.1 0.0 3.8 2 1 2 4 4 4 2 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2937 PF11157.8 OWF35086.1 - 0.57 9.9 6.8 1.1 9.0 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2937) 7tm_1 PF00001.21 OWF35087.1 - 1.1e-29 103.5 3.9 1.5e-29 103.1 3.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF35087.1 - 0.00023 21.0 8.8 0.00035 20.4 4.1 2.2 2 0 0 2 2 2 1 Olfactory receptor Otopetrin PF03189.13 OWF35087.1 - 0.037 12.8 6.9 1.8 7.3 4.1 2.1 2 0 0 2 2 2 0 Otopetrin DUF4834 PF16118.5 OWF35087.1 - 0.13 13.3 0.0 0.13 13.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Ctr PF04145.15 OWF35087.1 - 0.14 12.8 3.2 0.99 10.0 3.2 2.3 1 1 0 1 1 1 0 Ctr copper transporter family Pepsin-I3 PF06394.13 OWF35088.1 - 0.033 14.4 2.1 39 4.5 0.1 3.7 1 1 3 4 4 4 0 Pepsin inhibitor-3-like repeated domain zf-ACC PF17848.1 OWF35089.1 - 0.00053 20.0 0.5 4.1 7.5 0.0 3.7 4 0 0 4 4 4 2 Acetyl-coA carboxylase zinc finger domain SEEK1 PF15357.6 OWF35089.1 - 0.0078 16.4 6.5 0.21 11.8 1.3 2.4 1 1 1 2 2 2 2 Psoriasis susceptibility 1 candidate 1 Apidaecin PF00807.17 OWF35089.1 - 0.35 11.0 5.4 5 7.3 0.1 2.9 3 0 0 3 3 3 0 Apidaecin zf-C2HC PF01530.18 OWF35089.1 - 1.1 9.5 15.3 4.9 7.4 0.2 4.2 3 2 2 5 5 5 0 Zinc finger, C2HC type zf-ACC PF17848.1 OWF35090.1 - 0.12 12.5 10.1 63 3.8 0.0 7.3 9 0 0 9 9 9 0 Acetyl-coA carboxylase zinc finger domain Apidaecin PF00807.17 OWF35090.1 - 0.51 10.5 32.6 14 5.9 0.1 7.6 8 0 0 8 8 8 0 Apidaecin YycC PF14174.6 OWF35091.1 - 0.095 12.5 3.0 1.9e+02 2.0 0.0 5.6 6 1 1 7 7 7 0 YycC-like protein CheC PF04509.12 OWF35091.1 - 0.22 11.4 17.5 20 5.2 0.0 7.9 8 0 0 8 8 8 0 CheC-like family SEEK1 PF15357.6 OWF35091.1 - 0.42 10.7 41.5 0.98 9.6 2.1 6.4 1 1 6 7 7 7 0 Psoriasis susceptibility 1 candidate 1 Complex1_30kDa PF00329.19 OWF35092.1 - 1.1e-38 132.6 0.0 1.6e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Pkinase PF00069.25 OWF35093.1 - 4.2e-64 216.4 0.0 5.1e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35093.1 - 3.6e-31 108.4 0.0 4.9e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF35093.1 - 8.8e-05 21.6 0.0 0.0007 18.6 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OWF35093.1 - 0.00064 19.1 0.0 0.0017 17.8 0.0 1.6 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 OWF35093.1 - 0.0013 18.4 0.1 0.0022 17.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OWF35093.1 - 0.022 13.6 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OWF35093.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OWF35093.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OWF35094.1 - 2e-49 168.4 0.0 3.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 OWF35094.1 - 1.2e-29 102.0 26.4 4.6e-15 55.2 7.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 OWF35094.1 - 2.1e-29 102.6 0.0 4.6e-29 101.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 OWF35094.1 - 0.038 14.3 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 C2 domain C1_2 PF03107.16 OWF35094.1 - 0.062 13.6 20.5 0.3 11.4 7.1 2.5 2 0 0 2 2 2 0 C1 domain Haspin_kinase PF12330.8 OWF35094.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Zf_RING PF16744.5 OWF35094.1 - 0.11 12.6 12.2 0.61 10.2 3.5 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger ATG7_N PF16420.5 OWF35095.1 - 2.3e-101 339.4 0.0 3e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OWF35095.1 - 3.1e-48 164.3 0.0 5.8e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OWF35095.1 - 0.024 14.7 0.0 0.062 13.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MeaB PF03308.16 OWF35095.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ISG65-75 PF11727.8 OWF35096.1 - 1.1 8.4 3.9 12 5.1 0.1 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein DivIC PF04977.15 OWF35097.1 - 0.053 13.3 0.5 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator S6PP_C PF08472.10 OWF35097.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal DUF948 PF06103.11 OWF35097.1 - 0.96 9.8 5.9 1.4 9.3 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMEM187 PF15100.6 OWF35098.1 - 2.6e-77 259.7 11.3 3.1e-77 259.5 11.3 1.0 1 0 0 1 1 1 1 TMEM187 protein family Kelch_3 PF13415.6 OWF35099.1 - 3.8e-29 100.4 6.0 2.2e-05 24.6 0.0 7.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF35099.1 - 1.5e-28 98.3 1.5 0.00062 19.7 0.0 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OWF35099.1 - 3.7e-26 90.9 0.6 0.00021 21.2 0.0 6.8 4 2 2 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 OWF35099.1 - 6.5e-19 67.2 1.8 3.5e-05 23.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OWF35099.1 - 1.8e-16 59.7 4.9 0.14 12.5 0.0 6.7 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OWF35099.1 - 3.3e-14 52.2 1.0 0.013 15.5 0.0 6.5 6 0 0 6 6 6 5 Kelch motif fn3 PF00041.21 OWF35099.1 - 1.6e-07 31.6 0.4 0.053 13.9 0.0 4.2 5 0 0 5 5 5 2 Fibronectin type III domain CARD PF00619.21 OWF35100.1 - 5.5e-08 32.7 0.2 1.9e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Caspase recruitment domain DASH_Dam1 PF08653.10 OWF35100.1 - 0.3 10.9 1.8 1.1 9.2 0.3 2.9 2 1 0 2 2 2 0 DASH complex subunit Dam1 Gp-FAR-1 PF05823.12 OWF35100.1 - 1.3 9.4 14.0 0.32 11.4 3.1 3.2 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) COX4 PF02936.14 OWF35100.1 - 2.9 7.9 7.0 0.79 9.7 2.0 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV EF-G-binding_N PF07299.11 OWF35100.1 - 9.2 6.9 9.1 1.5e+02 3.0 6.0 3.8 3 1 0 3 3 3 0 Elongation factor G-binding protein, N-terminal APG6_N PF17675.1 OWF35100.1 - 9.6 6.7 44.0 6.7 7.3 21.3 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region FancD2 PF14631.6 OWF35101.1 - 0 1651.3 5.7 0 1650.9 5.7 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 OWF35101.1 - 0.0002 21.7 2.2 0.00086 19.6 0.0 3.0 3 0 0 3 3 3 1 FANCI solenoid 2 RNase_H2_suC PF08615.11 OWF35101.1 - 0.0084 16.3 1.0 0.2 11.8 0.0 3.0 3 0 0 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) 7tm_1 PF00001.21 OWF35102.1 - 5.6e-12 45.5 21.6 9.3e-12 44.8 21.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) O-FucT PF10250.9 OWF35103.1 - 0.00016 21.5 0.1 0.00024 20.9 0.1 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NodZ PF05830.11 OWF35103.1 - 0.0017 17.2 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) Glyco_transf_11 PF01531.16 OWF35103.1 - 0.0056 15.9 0.7 0.014 14.6 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 11 Ank_2 PF12796.7 OWF35105.1 - 2.5e-24 85.7 0.2 2.8e-10 40.6 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF35105.1 - 5.5e-21 74.4 0.1 2.5e-07 30.9 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF35105.1 - 6.5e-16 58.0 0.3 2.1e-05 24.8 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OWF35105.1 - 1.2e-15 57.6 0.1 1.9e-05 25.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF35105.1 - 5.7e-12 44.7 0.1 0.00011 22.3 0.1 4.5 5 1 0 5 5 5 2 Ankyrin repeat zf-MYND PF01753.18 OWF35105.1 - 3.6e-08 33.4 13.4 7.8e-08 32.3 13.4 1.6 1 0 0 1 1 1 1 MYND finger Ins_P5_2-kin PF06090.12 OWF35106.1 - 4.1e-62 210.5 0.0 1.5e-36 126.5 0.0 2.0 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase wnt PF00110.19 OWF35107.1 - 1e-117 393.2 25.2 1.1e-117 393.0 25.2 1.0 1 0 0 1 1 1 1 wnt family PH PF00169.29 OWF35108.1 - 1.1e-15 58.0 0.0 2.6e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 PH domain DEP PF00610.21 OWF35108.1 - 8.8e-11 41.7 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_9 PF15410.6 OWF35108.1 - 0.008 16.5 0.0 2.4 8.6 0.0 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 OWF35108.1 - 0.024 15.0 3.8 0.62 10.5 0.1 3.1 2 2 0 2 2 2 0 Pleckstrin homology domain HMG_box_2 PF09011.10 OWF35109.1 - 3.1e-33 114.2 12.2 4.3e-20 72.1 3.1 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 OWF35109.1 - 4.5e-29 100.7 11.0 5.5e-15 55.5 1.9 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box Protamine_like PF06382.11 OWF35109.1 - 0.02 15.1 0.1 0.02 15.1 0.1 2.2 1 1 0 2 2 2 0 Protamine and protamine like HMG_box_5 PF14887.6 OWF35109.1 - 0.041 13.9 8.2 0.4 10.7 0.8 2.3 1 1 1 2 2 2 0 HMG (high mobility group) box 5 YABBY PF04690.13 OWF35109.1 - 0.54 10.8 2.9 0.29 11.7 0.4 1.7 1 1 1 2 2 2 0 YABBY protein NOA36 PF06524.12 OWF35109.1 - 0.59 9.4 17.9 0.087 12.1 14.4 1.5 2 0 0 2 2 2 0 NOA36 protein Telethonin PF09470.10 OWF35110.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Telethonin protein ComS PF17584.2 OWF35110.1 - 0.075 12.6 0.2 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacillus competence protein S Cadherin PF00028.17 OWF35111.1 - 3.7e-225 729.3 85.2 5.2e-19 68.5 0.1 17.5 17 0 0 17 17 17 17 Cadherin domain Cadherin_2 PF08266.12 OWF35111.1 - 4.1e-16 58.6 0.0 0.19 11.6 0.0 9.2 9 0 0 9 9 9 6 Cadherin-like Cadherin_3 PF16184.5 OWF35111.1 - 1.2e-15 57.4 45.5 0.03 14.3 0.1 12.9 14 0 0 14 14 14 8 Cadherin-like Cadherin_4 PF17803.1 OWF35111.1 - 0.0039 17.8 5.2 0.0039 17.8 5.2 18.6 18 1 0 18 18 18 11 Bacterial cadherin-like domain Cation_ATPase_C PF00689.21 OWF35112.1 - 1.2e-40 139.1 2.2 1.2e-40 139.1 2.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OWF35112.1 - 4.6e-35 120.8 3.2 1e-26 93.6 0.8 3.7 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 OWF35112.1 - 1.1e-18 67.1 0.0 2.5e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) ATP_Ca_trans_C PF12424.8 OWF35112.1 - 4.1e-14 52.8 1.1 4.1e-14 52.8 1.1 2.3 2 0 0 2 2 2 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase_N PF00690.26 OWF35112.1 - 3.2e-11 42.8 0.0 7.7e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 OWF35112.1 - 4.7e-11 43.4 0.2 6.5e-10 39.7 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OWF35112.1 - 1e-05 25.4 5.8 6e-05 22.9 0.4 3.1 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase LRRC37AB_C PF14914.6 OWF35112.1 - 0.0081 16.1 1.0 0.88 9.5 0.4 2.6 2 0 0 2 2 2 1 LRRC37A/B like protein 1 C-terminal domain RIFIN PF02009.16 OWF35112.1 - 0.016 15.2 0.2 0.032 14.1 0.2 1.5 1 0 0 1 1 1 0 Rifin Ferlin_C PF16165.5 OWF35112.1 - 4.6 7.2 7.5 1.5 8.8 0.0 2.9 2 1 0 2 2 2 0 Ferlin C-terminus NnrS PF05940.12 OWF35112.1 - 4.8 6.4 7.2 1.7 8.0 0.8 2.8 3 0 0 3 3 3 0 NnrS protein Peptidase_M20 PF01546.28 OWF35113.1 - 3.5e-37 128.1 0.0 5.1e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OWF35113.1 - 5.2e-13 48.9 0.0 9.6e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OWF35113.1 - 9.8e-07 28.6 0.0 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 DUF3402 PF11882.8 OWF35114.1 - 4.3e-103 345.9 14.1 3.1e-65 221.1 4.2 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF3402) N1221 PF07923.13 OWF35114.1 - 1.2e-43 149.4 0.0 2.1e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Linker_histone PF00538.19 OWF35115.1 - 3.2e-25 88.3 4.0 3.2e-25 88.3 4.0 2.2 2 1 1 3 3 3 1 linker histone H1 and H5 family Forkhead PF00250.18 OWF35115.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Forkhead domain Sugar_tr PF00083.24 OWF35116.1 - 2.6e-116 389.2 31.6 2e-88 297.2 19.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF35116.1 - 1.2e-34 119.8 32.0 3.2e-30 105.2 22.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OWF35116.1 - 0.00019 20.0 4.1 0.00033 19.2 4.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AIG1 PF04548.16 OWF35116.1 - 0.0049 16.2 0.2 0.01 15.2 0.2 1.5 1 0 0 1 1 1 1 AIG1 family PSI PF01437.25 OWF35116.1 - 0.33 11.5 7.5 0.85 10.2 7.5 1.8 1 1 0 1 1 1 0 Plexin repeat PSI_integrin PF17205.3 OWF35116.1 - 0.44 10.3 8.5 1 9.1 8.5 1.7 1 1 0 1 1 1 0 Integrin plexin domain DUF3165 PF11364.8 OWF35116.1 - 0.56 10.6 16.9 0.11 12.9 1.8 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3165) Peptidase_M24 PF00557.24 OWF35117.1 - 9.1e-40 136.6 0.3 1.3e-39 136.0 0.3 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 LZ_Tnp_IS66 PF13007.7 OWF35117.1 - 6 7.7 8.2 14 6.5 0.4 2.4 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain POT1 PF02765.17 OWF35118.1 - 7.7e-31 106.8 0.0 3e-30 104.9 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 OWF35118.1 - 1.9e-25 89.5 0.0 1.3e-24 86.9 0.0 2.3 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein tRNA_anti-codon PF01336.25 OWF35118.1 - 9.3e-06 25.5 0.3 0.28 11.2 0.1 4.0 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain Pkinase PF00069.25 OWF35119.1 - 3.3e-44 151.2 1.5 7.4e-44 150.1 0.0 2.3 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35119.1 - 5.7e-27 94.6 0.0 1.7e-26 93.1 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_ULD PF18396.1 OWF35119.1 - 1.7e-12 47.1 0.0 5.1e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain TBK1_CCD1 PF18394.1 OWF35119.1 - 4.6e-08 32.9 19.5 8.4e-08 32.1 19.5 1.4 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Kinase-like PF14531.6 OWF35119.1 - 1.1e-05 24.9 0.0 4.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Calx-beta PF03160.14 OWF35120.1 - 2.8e-52 175.0 11.6 7.3e-18 64.6 0.9 3.5 3 0 0 3 3 3 3 Calx-beta domain Calx-beta PF03160.14 OWF35121.1 - 1.5e-88 291.4 24.5 6.1e-19 68.0 0.3 5.8 6 0 0 6 6 6 5 Calx-beta domain DUF3524 PF12038.8 OWF35122.1 - 5.9e-71 237.7 0.3 9e-71 237.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 OWF35122.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OWF35122.1 - 0.11 12.9 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Pkinase PF00069.25 OWF35123.1 - 2e-52 178.1 0.0 2.3e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35123.1 - 1.7e-21 76.7 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF35123.1 - 0.0011 18.0 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OWF35123.1 - 0.0038 16.3 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 OWF35123.1 - 0.0093 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OWF35123.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OWF35123.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Globin PF00042.22 OWF35123.1 - 0.15 12.6 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Globin Man-6-P_recep PF02157.15 OWF35124.1 - 2.3e-16 59.7 0.0 6.7e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OWF35124.1 - 2.4e-11 44.0 0.0 3.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OWF35124.1 - 0.0002 21.4 1.4 0.0011 19.1 0.9 1.9 1 1 1 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 OWF35125.1 - 2.6e-16 60.3 0.0 4.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF35125.1 - 1.8e-14 53.4 0.1 6.1e-12 45.2 0.1 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate receptor CIMR PF00878.18 OWF35125.1 - 1.2e-07 31.9 3.7 0.00028 21.0 2.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Glycos_transf_2 PF00535.26 OWF35126.1 - 3.7e-28 98.5 0.0 7.6e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF35126.1 - 2.4e-14 53.7 0.1 4.1e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 OWF35126.1 - 1.1e-05 25.0 0.1 2.8e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF35126.1 - 1.9e-05 24.3 0.0 9.3e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 OWF35126.1 - 4.8e-05 23.4 0.0 8.8e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 OWF35126.1 - 0.04 14.6 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OWF35126.1 - 0.059 13.0 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Peptidase_C69 PF03577.15 OWF35127.1 - 1.1e-11 44.3 0.0 2.1e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 OWF35127.1 - 0.00019 21.2 0.0 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MFS_1 PF07690.16 OWF35130.1 - 2e-16 59.8 35.1 2e-16 59.8 35.1 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM174 PF15029.6 OWF35130.1 - 0.063 13.0 0.8 0.12 12.0 0.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 Syndecan PF01034.20 OWF35130.1 - 1.3 8.9 4.8 0.91 9.5 0.1 2.9 2 1 0 2 2 2 0 Syndecan domain DUF92 PF01940.16 OWF35130.1 - 4.1 6.8 13.9 0.53 9.7 0.6 3.3 2 1 1 3 3 3 0 Integral membrane protein DUF92 MFS_1 PF07690.16 OWF35131.1 - 3.6e-14 52.4 47.7 7.6e-08 31.7 17.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Pam17 PF08566.10 OWF35131.1 - 0.54 10.1 2.7 16 5.3 0.3 2.7 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 MFS_3 PF05977.13 OWF35131.1 - 1.7 6.9 14.2 0.6 8.4 4.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector CoA_binding_3 PF13727.6 OWF35131.1 - 6.5 6.7 10.4 0.13 12.3 1.0 2.6 2 0 0 2 2 2 0 CoA-binding domain Abhydrolase_3 PF07859.13 OWF35132.1 - 1.9e-53 181.5 0.0 3.6e-41 141.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OWF35132.1 - 3.1e-10 39.6 0.1 9.7e-10 37.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OWF35132.1 - 1.8e-05 23.8 0.0 2.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OWF35132.1 - 0.00012 21.7 0.0 0.00034 20.2 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 OWF35132.1 - 0.01 14.6 0.0 0.024 13.3 0.0 1.6 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 OWF35132.1 - 0.018 15.2 0.0 0.078 13.1 0.0 1.9 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OWF35132.1 - 0.018 14.7 0.4 0.21 11.2 0.4 2.2 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 OWF35132.1 - 0.071 12.6 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF3987 PF13148.6 OWF35133.1 - 0.17 10.8 2.1 0.32 10.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TPR_6 PF13174.6 OWF35133.1 - 0.33 11.7 1.6 46 4.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OWF35133.1 - 0.33 11.0 0.0 0.33 11.0 0.0 3.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain CarD_CdnL_TRCF PF02559.16 OWF35133.1 - 0.34 11.6 3.5 0.73 10.6 0.3 2.5 2 0 0 2 2 2 0 CarD-like/TRCF domain TPR_8 PF13181.6 OWF35133.1 - 0.44 10.9 7.9 91 3.7 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF35133.1 - 0.44 10.5 7.0 12 5.9 0.2 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF1104 PF06518.11 OWF35133.1 - 0.93 9.9 9.5 0.12 12.8 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DnaJ PF00226.31 OWF35133.1 - 3.4 7.9 8.8 0.16 12.1 0.6 2.9 2 2 1 3 3 3 0 DnaJ domain Pkinase_Tyr PF07714.17 OWF35134.1 - 7.5e-62 208.9 0.0 1.1e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF35134.1 - 2.1e-27 96.2 0.0 3.4e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Stevor PF17410.2 OWF35134.1 - 0.24 10.9 1.4 0.43 10.1 1.4 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EGF PF00008.27 OWF35134.1 - 3.1 8.2 26.2 1.1 9.7 13.6 2.9 2 0 0 2 2 2 0 EGF-like domain Fasciclin PF02469.22 OWF35135.1 - 9.2e-55 184.3 0.1 9.6e-28 97.0 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain Pkinase_Tyr PF07714.17 OWF35137.1 - 4e-58 196.7 0.0 5.9e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF35137.1 - 1.7e-21 76.8 0.0 2.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35138.1 - 2.8e-59 200.5 0.0 4.1e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF35138.1 - 1.6e-23 83.4 0.0 2.6e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ACBP PF00887.19 OWF35139.1 - 3.2e-31 107.4 0.2 3.7e-31 107.2 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Par3_HAL_N_term PF12053.8 OWF35140.1 - 6.5e-38 128.8 0.4 1.4e-37 127.8 0.4 1.6 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins PDZ PF00595.24 OWF35140.1 - 2e-37 127.4 6.7 1.5e-14 54.1 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 OWF35140.1 - 2.5e-17 62.5 0.5 3.4e-05 23.6 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OWF35140.1 - 5.6e-15 55.4 3.0 3.1e-06 27.4 0.0 4.0 4 0 0 4 4 4 3 PDZ domain Arrestin_N PF00339.29 OWF35141.1 - 2.2e-10 40.8 0.4 2.2e-06 27.8 0.0 2.9 2 2 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF35141.1 - 1.6e-09 38.3 1.2 8e-09 36.1 0.9 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF5432 PF17497.2 OWF35142.1 - 0.86 9.7 6.7 14 5.8 0.3 4.1 1 1 3 4 4 4 0 Family of unknown function (DUF5432) Nuc_recep-AF1 PF11825.8 OWF35142.1 - 2.7 8.1 7.6 1.6 8.8 3.6 2.2 1 1 1 2 2 2 0 Nuclear/hormone receptor activator site AF-1 DUF2756 PF10956.8 OWF35142.1 - 3.4 8.2 11.0 16 6.1 0.2 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2756) 7tm_1 PF00001.21 OWF35143.1 - 6.4e-55 186.3 12.5 8.7e-55 185.9 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF35143.1 - 9.1e-14 51.4 13.4 1.2e-13 51.0 13.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF35143.1 - 0.0007 19.3 16.1 0.0019 17.9 16.0 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4064 PF13273.6 OWF35143.1 - 2.3 8.5 11.4 0.086 13.1 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Symplekin_C PF12295.8 OWF35144.1 - 0.0041 17.2 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal LSDAT_euk PF18139.1 OWF35146.1 - 6.8e-10 38.8 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM Ion_trans PF00520.31 OWF35146.1 - 1.8e-08 34.0 15.5 3.8e-08 32.9 15.5 1.6 1 0 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 OWF35146.1 - 5.3e-07 29.1 0.0 9.6e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote OATP PF03137.20 OWF35146.1 - 0.16 10.2 2.5 0.14 10.4 0.2 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Apis_Csd PF11671.8 OWF35146.1 - 7.3 6.6 8.2 0.45 10.5 1.6 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein LSDAT_euk PF18139.1 OWF35149.1 - 6.2e-09 35.6 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF35149.1 - 7.7e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 OWF35149.1 - 1.8 7.7 12.4 10 5.2 12.4 2.1 1 1 0 1 1 1 0 Ion transport protein PMP22_Claudin PF00822.20 OWF35151.1 - 0.042 13.7 1.1 0.061 13.2 1.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 OWF35151.1 - 0.1 12.1 1.2 0.15 11.5 0.6 1.5 1 1 0 1 1 1 0 Clc-like Claudin_2 PF13903.6 OWF35153.1 - 0.00011 22.0 1.0 0.00028 20.7 1.1 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction FAM176 PF14851.6 OWF35153.1 - 0.087 12.5 0.2 0.087 12.5 0.2 1.7 2 0 0 2 2 2 0 FAM176 family Zip PF02535.22 OWF35153.1 - 0.13 11.4 2.9 0.83 8.8 0.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 OWF35153.1 - 7.1 6.4 8.7 20 4.9 8.7 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Jun PF03957.13 OWF35155.1 - 5.9e-09 36.1 16.6 3.4 7.5 0.1 8.0 1 1 7 8 8 8 8 Jun-like transcription factor GST_N_5 PF18485.1 OWF35155.1 - 2.9e-07 30.7 0.1 31 5.0 0.0 6.6 1 1 8 9 9 9 5 Glutathione S-transferase, N-terminal domain Calcipressin PF04847.12 OWF35155.1 - 1.9 8.2 3.5 1.1e+02 2.4 0.0 4.4 2 2 5 7 7 7 0 Calcipressin Sulfotransfer_1 PF00685.27 OWF35156.1 - 5.6e-39 134.2 0.0 8.6e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF35156.1 - 7.2e-17 62.5 0.0 3.1e-10 40.8 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family eIF_4EBP PF05456.11 OWF35157.1 - 2.8e-41 140.1 0.8 3.3e-41 139.8 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Ank_2 PF12796.7 OWF35158.1 - 1.3e-151 493.5 23.5 1.5e-20 73.6 0.3 11.8 4 2 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35158.1 - 1e-125 408.6 5.3 1.8e-10 41.1 0.0 15.4 9 4 7 16 16 16 16 Ankyrin repeats (many copies) Ank PF00023.30 OWF35158.1 - 3.4e-119 384.6 46.0 2.5e-08 34.0 0.0 23.8 24 0 0 24 24 24 21 Ankyrin repeat Ank_3 PF13606.6 OWF35158.1 - 8.3e-108 339.2 24.5 1.1e-05 25.4 0.0 24.8 25 0 0 25 25 25 22 Ankyrin repeat Ank_5 PF13857.6 OWF35158.1 - 8.5e-98 319.1 30.9 5.3e-09 36.2 0.0 19.8 6 4 11 19 19 19 19 Ankyrin repeats (many copies) KH_1 PF00013.29 OWF35158.1 - 1.3e-14 53.8 1.8 4.2e-14 52.1 1.8 2.0 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 OWF35158.1 - 0.012 15.4 0.0 0.056 13.3 0.0 2.2 1 0 0 1 1 1 0 KH domain PAM2 PF07145.15 OWF35158.1 - 0.088 12.5 0.3 0.22 11.3 0.3 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TMF_TATA_bd PF12325.8 OWF35159.1 - 4.4e-32 110.7 15.5 4.4e-32 110.7 15.5 8.3 2 1 5 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OWF35159.1 - 1.7e-16 60.0 18.7 1.7e-16 60.0 18.7 10.1 6 2 4 10 10 10 3 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 OWF35159.1 - 0.0051 16.9 9.1 0.0051 16.9 9.1 6.8 6 1 2 8 8 8 2 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 OWF35159.1 - 0.0061 17.1 1.7 0.0061 17.1 1.7 10.4 4 3 7 12 12 12 2 SlyX DUF4464 PF14713.6 OWF35160.1 - 1.2e-99 332.4 0.4 1.3e-99 332.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) TGF_beta PF00019.20 OWF35162.1 - 7.5e-24 84.7 0.0 1.9e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 OWF35162.1 - 3e-09 37.0 0.2 3e-09 37.0 0.2 2.3 2 1 0 2 2 2 1 TGF-beta propeptide zf-C3HC4_2 PF13923.6 OWF35163.1 - 6e-13 48.4 6.8 6e-13 48.4 6.8 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF35163.1 - 1.6e-11 43.9 6.5 5.3e-11 42.2 6.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF35163.1 - 1.2e-10 41.2 10.6 1.9e-10 40.6 8.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF35163.1 - 1.9e-10 40.9 6.0 1.9e-10 40.9 6.0 2.0 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF35163.1 - 7.2e-07 29.3 6.6 7.2e-07 29.3 6.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF35163.1 - 9.7e-07 28.6 6.0 1.4e-06 28.1 4.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF35163.1 - 3.8e-06 27.1 6.8 3.2e-05 24.1 6.8 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF35163.1 - 3.5e-05 23.7 5.3 0.0001 22.2 5.3 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF35163.1 - 0.00028 20.7 7.6 0.00052 19.8 6.5 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 OWF35163.1 - 0.00045 20.3 0.2 0.0012 19.0 0.0 1.7 2 0 0 2 2 2 1 U-box domain Sina PF03145.16 OWF35163.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-RING_11 PF17123.5 OWF35163.1 - 0.017 14.9 5.8 0.055 13.2 5.8 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 OWF35163.1 - 0.028 14.2 6.7 0.063 13.1 3.3 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 OWF35163.1 - 0.058 13.5 3.8 0.15 12.2 3.8 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OWF35163.1 - 0.06 13.4 3.3 0.1 12.7 2.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OWF35163.1 - 0.24 11.3 4.8 0.15 12.0 2.2 2.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein IBR PF01485.21 OWF35163.1 - 1.3 9.3 9.5 8.3 6.7 7.8 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain C2 PF00168.30 OWF35164.1 - 6.5e-32 109.9 0.2 1.2e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 OWF35164.1 - 0.00021 20.9 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 CEP76 C2 domain DUF4229 PF14012.6 OWF35165.1 - 0.023 14.8 1.9 0.023 14.8 1.9 6.7 5 2 1 6 6 6 0 Protein of unknown function (DUF4229) zf-C2H2 PF00096.26 OWF35166.1 - 4.2e-19 67.9 36.2 0.00015 22.1 1.7 7.5 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF35166.1 - 3.2e-18 64.8 32.9 0.0061 17.3 0.7 7.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF35166.1 - 5e-14 51.9 28.8 3.8e-05 23.6 1.5 7.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 OWF35166.1 - 2.9e-06 27.5 20.2 0.35 11.3 0.6 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type ELM2 PF01448.24 OWF35166.1 - 3.8e-05 24.3 0.0 0.00016 22.3 0.0 2.2 1 0 0 1 1 1 1 ELM2 domain zf-H2C2_2 PF13465.6 OWF35166.1 - 7.9e-05 22.9 41.3 0.0029 18.0 0.8 8.2 9 0 0 9 9 8 3 Zinc-finger double domain zf-Di19 PF05605.12 OWF35166.1 - 0.00019 21.7 21.2 0.0014 18.9 3.1 5.1 4 1 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 OWF35166.1 - 0.001 18.9 0.1 0.001 18.9 0.1 3.8 4 0 0 4 4 3 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 OWF35166.1 - 0.0037 17.5 27.1 0.04 14.2 0.6 6.7 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding Myb_DNA-binding PF00249.31 OWF35166.1 - 0.0051 17.0 0.2 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_8 PF15909.5 OWF35166.1 - 0.12 12.7 13.0 3.7 7.9 0.1 4.6 3 1 1 4 4 4 0 C2H2-type zinc ribbon PASTA PF03793.19 OWF35166.1 - 0.13 12.1 3.6 0.084 12.7 0.4 2.4 2 0 0 2 2 2 0 PASTA domain FYVE PF01363.21 OWF35166.1 - 0.14 12.3 8.4 8.5 6.6 4.9 3.8 3 0 0 3 3 3 0 FYVE zinc finger zf-C2H2_9 PF16293.5 OWF35166.1 - 0.29 11.0 5.3 2.2 8.2 0.2 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) GBP PF02263.19 OWF35167.1 - 5.4e-93 311.0 0.0 7.3e-93 310.6 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OWF35167.1 - 0.00012 21.6 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 OWF35167.1 - 0.0077 16.6 0.2 0.026 14.9 0.0 1.9 2 0 0 2 2 2 1 T-lymphoma invasion and metastasis CC-Ex domain DUF2207 PF09972.9 OWF35167.1 - 0.056 12.2 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) B56 PF01603.20 OWF35168.1 - 2.7e-197 655.8 8.5 3.5e-197 655.4 8.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PCNP PF15473.6 OWF35168.1 - 5.5 7.7 12.1 1.1 10.0 8.5 1.6 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family DAP3 PF10236.9 OWF35169.1 - 0.034 13.3 0.2 0.056 12.6 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 cwf21 PF08312.12 OWF35170.1 - 0.76 10.0 4.8 4.4 7.5 0.2 3.3 3 0 0 3 3 3 0 cwf21 domain FHA PF00498.26 OWF35171.1 - 2.3e-17 63.1 0.0 5.2e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 OWF35171.1 - 3.7e-09 36.3 7.6 7.5e-09 35.3 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF35171.1 - 1e-08 34.9 11.5 3.5e-08 33.2 11.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF35171.1 - 3e-08 33.4 10.0 7.2e-08 32.1 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF35171.1 - 3.7e-08 33.6 9.7 9.9e-08 32.2 9.7 1.8 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 OWF35171.1 - 1.1e-07 32.0 0.5 5.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_UBOX PF13445.6 OWF35171.1 - 9.6e-06 25.5 4.9 2.9e-05 24.0 4.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OWF35171.1 - 2.8e-05 24.3 9.1 0.00011 22.4 9.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OWF35171.1 - 2.9e-05 24.1 10.2 7.2e-05 22.9 10.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OWF35171.1 - 0.00033 20.7 5.7 0.00098 19.2 5.7 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 OWF35171.1 - 0.0012 18.7 9.9 0.0033 17.4 9.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 OWF35171.1 - 0.0065 16.3 2.7 0.0065 16.3 2.7 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OWF35171.1 - 0.013 15.6 1.4 0.034 14.2 1.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FHA_2 PF17913.1 OWF35171.1 - 0.013 15.7 0.2 0.062 13.5 0.1 2.2 1 1 1 2 2 2 0 FHA domain Prok-RING_4 PF14447.6 OWF35171.1 - 0.13 12.1 7.5 0.3 11.0 7.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF35171.1 - 0.19 11.5 8.6 0.74 9.7 8.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-LITAF-like PF10601.9 OWF35171.1 - 1.1 9.6 7.5 5.3 7.4 7.6 1.9 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain DZR PF12773.7 OWF35171.1 - 1.6 8.8 6.8 7.5 6.7 6.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF3584 PF12128.8 OWF35171.1 - 3.5 5.0 43.2 6 4.2 43.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-ribbon_3 PF13248.6 OWF35171.1 - 4.7 6.8 10.3 4.2 6.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_11 PF17123.5 OWF35171.1 - 5 6.9 6.3 14 5.5 6.3 1.9 1 0 0 1 1 1 0 RING-like zinc finger Ribosomal_S30 PF04758.14 OWF35172.1 - 2.4e-28 98.1 10.5 3.3e-28 97.7 10.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 OWF35172.1 - 6.5e-09 35.4 0.0 9.6e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L36e PF01158.18 OWF35173.1 - 0.0078 16.4 0.3 0.018 15.3 0.3 1.6 1 1 0 1 1 1 1 Ribosomal protein L36e DUF948 PF06103.11 OWF35173.1 - 0.03 14.6 0.8 1.9 8.8 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Globin PF00042.22 OWF35175.1 - 7.1e-20 71.6 0.8 9.6e-20 71.2 0.8 1.2 1 0 0 1 1 1 1 Globin IFN-gamma PF00714.17 OWF35175.1 - 0.037 13.9 0.7 0.09 12.6 0.7 1.7 1 0 0 1 1 1 0 Interferon gamma Fibrinogen_BP PF08017.11 OWF35177.1 - 1.1e-05 24.1 241.6 0.00096 17.7 129.1 2.0 1 1 1 2 2 2 2 Fibrinogen binding protein Globin PF00042.22 OWF35178.1 - 2.6e-19 69.8 0.0 4.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Globin SGL PF08450.12 OWF35179.1 - 5.2e-58 196.5 0.5 5.8e-58 196.4 0.5 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF839 PF05787.13 OWF35179.1 - 0.00032 20.0 0.0 0.00042 19.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) NHL PF01436.21 OWF35179.1 - 0.0031 17.5 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 NHL repeat Reg_prop PF07494.11 OWF35179.1 - 0.0078 16.3 2.2 0.88 10.0 0.3 3.3 3 0 0 3 3 3 1 Two component regulator propeller PQQ_3 PF13570.6 OWF35179.1 - 0.01 16.3 0.2 3.1 8.4 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Str_synth PF03088.16 OWF35179.1 - 0.18 11.9 0.0 0.63 10.2 0.0 1.9 2 1 1 3 3 3 0 Strictosidine synthase Neurexophilin PF06312.12 OWF35180.1 - 0.00033 20.2 0.5 0.001 18.5 0.5 1.8 1 1 0 1 1 1 1 Neurexophilin RsgI_N PF12791.7 OWF35180.1 - 0.031 14.2 0.1 0.099 12.6 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Filamin PF00630.19 OWF35180.1 - 0.057 14.3 0.7 0.47 11.3 0.0 2.5 3 0 0 3 3 3 0 Filamin/ABP280 repeat SPDY PF03771.16 OWF35181.1 - 0.11 12.4 0.1 3 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Fae PF08714.11 OWF35181.1 - 0.19 11.6 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) Neurexophilin PF06312.12 OWF35182.1 - 5.2e-05 22.8 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Neurexophilin RsgI_N PF12791.7 OWF35182.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Anti-sigma factor N-terminus Filamin PF00630.19 OWF35182.1 - 0.012 16.4 0.0 0.018 15.8 0.0 1.3 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF5348 PF17295.2 OWF35182.1 - 0.073 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Sulfotransfer_1 PF00685.27 OWF35183.1 - 8.9e-56 189.3 2.5 3.1e-55 187.5 2.5 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF35183.1 - 2.8e-06 27.9 0.6 1e-05 26.0 0.1 2.0 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF35184.1 - 3.4e-47 161.2 0.1 6.3e-47 160.3 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF35184.1 - 0.0011 19.4 0.0 0.0059 17.0 0.0 2.0 1 1 0 2 2 2 1 Sulfotransferase family DUF3470 PF11953.8 OWF35184.1 - 0.081 12.9 0.6 0.17 11.9 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) GLTT PF01744.20 OWF35186.1 - 5.5e-14 51.5 8.2 2.7e-06 27.0 0.2 3.3 2 1 1 3 3 3 3 GLTT repeat (6 copies) EGF PF00008.27 OWF35189.1 - 0.0015 18.8 0.2 0.0034 17.6 0.2 1.7 1 1 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 OWF35189.1 - 0.11 12.9 0.1 0.22 11.9 0.1 1.6 1 1 0 1 1 1 0 EGF-like domain Galactosyl_T PF01762.21 OWF35190.1 - 1.6e-41 142.3 0.9 2.3e-41 141.8 0.9 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF35190.1 - 0.045 13.2 1.1 0.079 12.4 1.1 1.4 1 1 0 1 1 1 0 Fringe-like MT-A70 PF05063.14 OWF35191.1 - 1.4e-59 200.9 0.1 3.2e-59 199.7 0.0 1.7 2 0 0 2 2 2 1 MT-A70 Ras PF00071.22 OWF35192.1 - 9.3e-39 132.6 0.0 1.2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF35192.1 - 3.9e-26 91.6 0.0 5.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF35192.1 - 6.1e-13 48.6 0.0 8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF35192.1 - 3.8e-07 29.7 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF35192.1 - 8.8e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF35192.1 - 0.00013 21.6 0.0 0.0038 16.8 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OWF35192.1 - 0.0011 18.4 0.0 0.0047 16.4 0.0 1.8 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF35192.1 - 0.036 14.0 0.1 0.5 10.2 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 OWF35192.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Metallophos PF00149.28 OWF35193.1 - 3.4e-17 63.6 4.6 4.4e-17 63.3 3.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OWF35193.1 - 9e-15 55.3 0.1 2.2e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OWF35193.1 - 6.6e-08 33.0 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain XPG_N PF00752.17 OWF35194.1 - 5.4e-34 116.7 0.0 1.2e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OWF35194.1 - 1.5e-29 102.2 0.0 3.7e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 OWF35194.1 - 9.1e-07 29.4 0.0 4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 OWF35194.1 - 0.00047 20.1 0.0 0.0021 18.0 0.0 2.0 2 1 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 OWF35194.1 - 0.0047 17.5 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DEAD PF00270.29 OWF35195.1 - 8.5e-47 159.2 0.2 2.5e-46 157.6 0.2 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF35195.1 - 1.6e-31 108.9 1.7 2.5e-30 105.1 0.3 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OWF35195.1 - 0.036 14.4 1.2 0.14 12.4 0.4 2.5 2 1 0 2 2 2 0 AAA domain Phage_integrase PF00589.22 OWF35195.1 - 0.49 10.2 0.0 0.49 10.2 0.0 3.7 4 2 0 4 4 4 0 Phage integrase family Mem_trans PF03547.18 OWF35195.1 - 0.73 8.2 1.9 0.83 8.0 0.1 1.9 2 0 0 2 2 2 0 Membrane transport protein Pkinase PF00069.25 OWF35196.1 - 1e-73 247.9 0.1 1.5e-73 247.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35196.1 - 6.5e-34 117.4 0.0 9.4e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF35196.1 - 4e-07 29.6 0.2 7.2e-06 25.5 0.0 2.5 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 OWF35196.1 - 0.008 15.6 0.1 0.018 14.4 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF35196.1 - 0.036 14.0 0.4 5.5 6.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OWF35196.1 - 0.058 13.0 2.3 5.6 6.5 0.1 3.1 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 OWF35197.1 - 1.9e-12 47.4 14.3 0.02 15.8 0.4 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OWF35197.1 - 0.0001 21.2 2.8 0.045 12.5 0.5 4.1 2 1 3 5 5 5 3 Nup133 N terminal like Nup160 PF11715.8 OWF35197.1 - 0.034 12.8 3.1 0.072 11.7 0.4 2.6 2 2 1 3 3 3 0 Nucleoporin Nup120/160 SUKH_6 PF14568.6 OWF35197.1 - 0.1 13.0 0.8 20 5.6 0.2 3.3 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall RSB_motif PF16294.5 OWF35198.1 - 2.8e-26 91.7 10.1 2.8e-26 91.7 10.1 12.6 5 2 4 10 10 10 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 OWF35198.1 - 1.1e-10 41.0 3.3 1.3e-09 37.5 1.4 2.6 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 OWF35198.1 - 3.6e-06 26.7 0.0 9.3e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VPS9 PF02204.18 OWF35199.1 - 6.5e-26 90.6 0.4 2e-25 89.0 0.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain EF-hand_7 PF13499.6 OWF35200.1 - 3e-05 24.4 0.4 0.00019 21.8 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF35200.1 - 0.00059 19.2 0.2 0.0041 16.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OWF35200.1 - 0.00069 19.3 0.1 0.0022 17.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain DUF963 PF06131.11 OWF35200.1 - 0.00079 18.8 5.7 0.0022 17.4 5.7 1.7 1 0 0 1 1 1 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) Pro_isomerase PF00160.21 OWF35201.1 - 1.1e-45 155.7 0.2 1.4e-45 155.4 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_14 PF18343.1 OWF35201.1 - 0.053 13.6 0.1 5.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Dda helicase SH3 domain Pro_isomerase PF00160.21 OWF35202.1 - 1.4e-47 161.9 0.1 2e-47 161.4 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3271 PF11675.8 OWF35202.1 - 0.034 13.4 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3271) Pro_isomerase PF00160.21 OWF35203.1 - 4.5e-47 160.2 0.1 6.3e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3271 PF11675.8 OWF35203.1 - 0.032 13.5 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3271) DUF563 PF04577.14 OWF35204.1 - 1.9e-20 73.9 0.0 1.1e-19 71.4 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF563) RCR PF12273.8 OWF35205.1 - 0.00063 20.4 0.6 0.0013 19.3 0.6 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CYYR1 PF10873.8 OWF35205.1 - 0.016 15.6 0.9 0.016 15.6 0.9 2.3 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 Mid2 PF04478.12 OWF35205.1 - 0.13 12.1 3.0 0.27 11.0 3.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Cadherin_C_2 PF16492.5 OWF35205.1 - 0.18 12.6 0.2 0.18 12.6 0.2 2.9 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal Gpi16 PF04113.14 OWF35206.1 - 2.1e-151 505.2 0.1 3e-150 501.4 0.1 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Pam17 PF08566.10 OWF35206.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 NFACT-C PF11923.8 OWF35206.1 - 1.7 8.6 4.9 3.6 7.5 4.9 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain JmjC PF02373.22 OWF35207.1 - 3.4e-25 88.7 1.4 6.2e-25 87.9 0.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 OWF35207.1 - 1.8e-13 50.2 2.1 3.8e-13 49.1 2.1 1.6 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 OWF35207.1 - 8.7e-08 32.7 0.0 2.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 OWF35207.1 - 0.023 15.1 0.5 0.023 15.1 0.5 2.0 2 0 0 2 2 2 0 C5HC2 zinc finger FokI_N PF02981.15 OWF35207.1 - 6.9 6.8 6.3 38 4.4 1.3 2.9 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain Ras PF00071.22 OWF35208.1 - 7.3e-63 211.0 0.1 8.7e-63 210.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF35208.1 - 1.8e-33 115.3 0.1 4.3e-33 114.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF35208.1 - 6.3e-13 48.6 0.1 7.7e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF35208.1 - 4.7e-05 23.4 0.0 7.3e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF35208.1 - 0.00027 20.3 0.0 0.00041 19.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF35208.1 - 0.00056 19.5 0.1 0.0034 16.9 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF35208.1 - 0.0012 18.8 0.2 0.27 11.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OWF35208.1 - 0.04 14.2 0.1 0.21 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 OWF35208.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 OWF35208.1 - 0.11 12.1 0.1 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain Snf7 PF03357.21 OWF35209.1 - 1.1e-49 168.3 9.3 1.7e-49 167.7 9.3 1.3 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 OWF35209.1 - 0.0069 16.8 2.6 0.0097 16.3 2.6 1.2 1 0 0 1 1 1 1 SYF2 splicing factor eIF-5_eIF-2B PF01873.17 OWF35209.1 - 0.017 15.0 1.0 0.031 14.2 1.0 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Snf7 PF03357.21 OWF35210.1 - 1.7e-42 145.0 7.6 2.2e-42 144.6 7.6 1.1 1 0 0 1 1 1 1 Snf7 Tropomodulin PF03250.14 OWF35210.1 - 0.01 15.9 3.3 0.01 15.9 3.3 1.9 2 1 0 2 2 2 0 Tropomodulin UvrC_HhH_N PF08459.11 OWF35210.1 - 0.028 14.4 0.3 0.042 13.7 0.3 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal SYF2 PF08231.12 OWF35210.1 - 0.25 11.7 1.8 0.3 11.5 1.8 1.3 1 1 0 1 1 1 0 SYF2 splicing factor Ribosomal_L13e PF01294.18 OWF35211.1 - 6.2e-82 273.8 8.1 6.2e-82 273.8 8.1 1.6 3 0 0 3 3 3 1 Ribosomal protein L13e 5_nucleotid_C PF02872.18 OWF35212.1 - 1.4e-41 142.3 0.0 2.4e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OWF35212.1 - 1.4e-07 32.3 0.4 2.2e-07 31.6 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAM131 PF15010.6 OWF35212.1 - 0.021 14.8 2.0 0.19 11.6 0.0 2.7 3 0 0 3 3 3 0 Putative cell signalling PCIF1_WW PF12237.8 OWF35213.1 - 1.5e-71 239.6 0.2 2.4e-71 238.8 0.2 1.4 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.26 OWF35213.1 - 3.5e-09 36.6 0.2 5.7e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 WW domain Katanin_con80 PF13925.6 OWF35214.1 - 7e-56 188.7 0.2 9.8e-56 188.2 0.2 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 OWF35214.1 - 1.7e-49 164.7 6.5 5.7e-13 49.1 0.7 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35214.1 - 3.5e-14 52.9 0.1 0.00038 20.7 0.0 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF35214.1 - 4.2e-09 36.6 0.0 0.034 14.0 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF35214.1 - 0.00012 21.2 0.0 0.0014 17.6 0.0 2.4 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OWF35214.1 - 0.001 17.8 0.1 2.7 6.5 0.0 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF35214.1 - 0.002 17.5 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain PD40 PF07676.12 OWF35214.1 - 0.065 13.2 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat CBF_beta PF02312.17 OWF35215.1 - 4.5e-78 260.7 4.2 6.2e-78 260.2 4.2 1.2 1 0 0 1 1 1 1 Core binding factor beta subunit Miff PF05644.11 OWF35215.1 - 0.0053 16.4 3.5 0.0077 15.9 3.5 1.2 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff DUF883 PF05957.13 OWF35215.1 - 1.7 9.3 5.3 1.2 9.7 3.6 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CAP PF00188.26 OWF35216.1 - 1.4e-20 74.4 6.8 6.7e-13 49.6 0.4 2.8 2 1 0 2 2 2 2 Cysteine-rich secretory protein family TMEM154 PF15102.6 OWF35217.1 - 9.5e-06 25.6 0.1 2.9e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 TMEM154 protein family WSC PF01822.19 OWF35217.1 - 0.00029 21.0 9.2 0.00029 21.0 9.2 2.6 2 0 0 2 2 2 1 WSC domain Adeno_E3_CR2 PF02439.15 OWF35217.1 - 0.00049 19.8 6.3 0.00092 18.9 6.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF3827 PF12877.7 OWF35217.1 - 0.0018 16.8 0.1 0.0027 16.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 OWF35217.1 - 0.013 16.4 0.0 0.051 14.5 0.0 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OWF35217.1 - 0.015 14.7 1.8 0.03 13.7 1.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Orf78 PF06024.12 OWF35217.1 - 0.016 15.5 0.3 0.051 13.9 0.0 2.1 2 0 0 2 2 1 0 Orf78 (ac78) ECSCR PF15820.5 OWF35217.1 - 0.016 15.0 0.1 0.045 13.6 0.1 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SCIMP PF15050.6 OWF35217.1 - 0.13 12.7 0.0 0.58 10.6 0.0 2.1 1 0 0 1 1 1 0 SCIMP protein UL42 PF17638.2 OWF35217.1 - 0.31 11.0 2.2 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 HCMV UL42 DUF4834 PF16118.5 OWF35217.1 - 0.33 11.9 0.0 0.33 11.9 0.0 2.2 3 0 0 3 3 1 0 Domain of unknown function (DUF4834) HALZ PF02183.18 OWF35217.1 - 1.5 9.1 4.7 4.9 7.5 0.8 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper LRAT PF04970.13 OWF35218.1 - 2.5e-08 34.3 7.2 2.5e-06 27.8 7.2 2.4 1 1 0 1 1 1 1 Lecithin retinol acyltransferase zf-HC5HC2H PF13771.6 OWF35219.1 - 1.8e-08 34.5 16.9 1.8e-08 34.5 16.9 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OWF35219.1 - 0.21 11.7 13.6 0.62 10.3 13.6 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain PepSY_TM_like_2 PF16357.5 OWF35220.1 - 0.06 13.3 0.6 0.11 12.5 0.6 1.4 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF5353 PF17304.2 OWF35220.1 - 0.11 12.2 0.6 0.68 9.7 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5353) Claudin_3 PF06653.11 OWF35220.1 - 3.9 7.4 11.6 2.1e+02 1.7 9.0 2.7 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Mito_carr PF00153.27 OWF35221.1 - 5.7e-61 202.5 5.3 3.7e-21 74.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAP PF03866.13 OWF35221.1 - 0.03 14.4 0.2 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) HMD PF03201.16 OWF35221.1 - 0.14 12.4 0.6 0.71 10.1 0.2 2.5 4 0 0 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase adh_short PF00106.25 OWF35222.1 - 2.1e-43 148.0 0.0 3.8e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF35222.1 - 8.5e-29 100.8 0.0 1.4e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF35222.1 - 1.8e-07 31.2 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 KR domain TGBp3 PF02495.17 OWF35222.1 - 0.0082 15.8 0.2 0.0082 15.8 0.2 1.8 2 0 0 2 2 2 1 Triple gene block 3 DUF2842 PF11003.8 OWF35222.1 - 0.13 12.5 2.3 0.25 11.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) SNAP PF14938.6 OWF35223.1 - 9.6e-10 38.3 5.2 1.7e-09 37.6 5.2 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OWF35223.1 - 0.00016 21.8 0.6 0.052 13.8 0.2 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF35223.1 - 0.00033 20.5 1.2 0.012 15.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF35223.1 - 0.0018 18.0 0.3 0.034 14.0 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF35223.1 - 0.017 15.3 0.5 0.29 11.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF35223.1 - 0.13 13.1 1.1 2 9.4 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF35223.1 - 0.14 12.8 0.0 0.14 12.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat G_glu_transpept PF01019.21 OWF35224.1 - 1.9e-166 554.9 0.0 2.3e-166 554.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3439 PF11921.8 OWF35224.1 - 2 8.4 5.9 1.1 9.3 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Fibrinogen_C PF00147.18 OWF35225.1 - 1.3e-33 116.7 5.3 1.8e-33 116.2 5.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CX9C PF16860.5 OWF35225.1 - 0.33 11.0 1.9 0.38 10.8 0.2 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sulfotransfer_1 PF00685.27 OWF35226.1 - 2.7e-40 138.5 0.1 4.4e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF35226.1 - 4.3e-16 60.0 0.0 2.4e-10 41.2 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family RasGEF PF00617.19 OWF35227.1 - 1.1e-52 178.8 2.2 1.1e-52 178.8 2.2 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OWF35227.1 - 1.4e-14 54.2 0.0 5.1e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Poty_PP PF08440.10 OWF35227.1 - 0.0062 15.7 1.1 0.013 14.6 1.1 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein ParB PF08775.10 OWF35227.1 - 0.18 12.3 3.0 0.31 11.5 1.1 2.4 2 1 1 3 3 3 0 ParB family Peptidase_S49_N PF08496.10 OWF35227.1 - 0.26 11.4 2.5 0.64 10.1 2.5 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1091 PF06477.13 OWF35227.1 - 0.32 11.5 1.3 2.2 8.8 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1091) bZIP_2 PF07716.15 OWF35227.1 - 5 7.3 7.7 2.9 8.0 2.8 2.7 2 0 0 2 2 2 0 Basic region leucine zipper 7tm_1 PF00001.21 OWF35228.1 - 1.8e-51 175.0 16.7 2.2e-51 174.7 16.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF35228.1 - 1.4e-11 44.2 15.7 3.3e-11 43.1 15.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF35228.1 - 1.7e-09 37.5 12.3 3.2e-09 36.5 12.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF35228.1 - 7.9e-05 22.4 21.5 0.0008 19.1 21.5 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF35228.1 - 0.018 14.8 12.5 0.051 13.3 12.5 1.8 1 1 0 1 1 1 0 Olfactory receptor DUF3593 PF12159.8 OWF35228.1 - 2.2 8.4 6.2 1.2 9.2 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3593) wnt PF00110.19 OWF35229.1 - 5.1e-78 262.8 33.1 6.3e-78 262.5 33.1 1.0 1 0 0 1 1 1 1 wnt family Sulfotransfer_2 PF03567.14 OWF35230.1 - 6.5e-31 108.1 4.9 6.3e-29 101.6 0.5 2.2 1 1 0 2 2 2 2 Sulfotransferase family Herpes_US9 PF06072.11 OWF35230.1 - 1.8 8.5 3.6 4.7 7.2 3.6 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DNA_ligase_A_M PF01068.21 OWF35231.1 - 1.2e-65 221.0 0.6 2.9e-65 219.8 0.6 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OWF35231.1 - 7.5e-47 159.9 0.1 1.9e-46 158.6 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OWF35231.1 - 1.1e-24 86.9 0.0 1.1e-24 86.9 0.0 2.9 2 1 1 3 3 3 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 OWF35231.1 - 3.4 7.7 6.8 17 5.5 0.0 3.3 3 0 0 3 3 3 0 DNA ligase OB-like domain Solute_trans_a PF03619.16 OWF35232.1 - 7.3e-53 179.8 8.1 8.4e-53 179.6 8.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha UNC-93 PF05978.16 OWF35234.1 - 2.1e-45 154.2 6.4 2.1e-45 154.2 6.4 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OWF35234.1 - 5.6e-16 58.4 33.9 7.3e-13 48.2 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 OWF35235.1 - 6.6e-22 77.1 0.0 9.6e-22 76.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OWF35235.1 - 0.027 14.4 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Apt1 PF10351.9 OWF35235.1 - 8.1 5.2 17.1 9.6 4.9 17.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PDT PF00800.18 OWF35236.1 - 1.1e-06 28.6 0.6 1.6e-06 28.1 0.6 1.2 1 0 0 1 1 1 1 Prephenate dehydratase Longin PF13774.6 OWF35236.1 - 0.00097 19.1 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OWF35236.1 - 0.018 14.8 3.8 0.029 14.1 3.8 1.3 1 0 0 1 1 1 0 Synaptobrevin ETRAMP PF09716.10 OWF35236.1 - 0.064 13.3 0.3 0.085 12.9 0.3 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ferlin_C PF16165.5 OWF35236.1 - 0.068 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Ferlin C-terminus WRW PF10206.9 OWF35237.1 - 6.3e-29 100.4 0.2 7.2e-29 100.2 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Aa_trans PF01490.18 OWF35239.1 - 2e-55 188.2 26.9 2.6e-55 187.8 26.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_85 PF03644.13 OWF35240.1 - 6.6e-96 321.3 1.5 1.1e-95 320.5 1.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 85 ArfGap PF01412.18 OWF35241.1 - 1.3e-36 125.2 0.2 2.7e-36 124.2 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OWF35241.1 - 2.2e-24 85.9 0.1 4.7e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 OWF35241.1 - 2.4e-06 27.8 1.2 0.067 13.5 0.2 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 OWF35241.1 - 4.8e-06 26.9 6.8 0.0019 18.6 1.5 3.9 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 OWF35241.1 - 3.3e-05 23.9 0.6 0.012 15.7 0.0 3.1 2 1 0 2 2 2 2 PH domain LRR_6 PF13516.6 OWF35242.1 - 4.9e-09 35.5 1.0 0.7 10.1 0.0 5.9 6 0 0 6 6 6 3 Leucine Rich repeat F-box PF00646.33 OWF35242.1 - 3.9e-08 33.0 3.1 2.1e-05 24.3 0.1 3.7 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.7 OWF35242.1 - 9.4e-05 22.7 4.7 0.0025 18.2 0.1 4.0 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF35242.1 - 0.00077 19.7 4.4 22 6.1 0.0 5.5 6 1 0 6 6 6 2 Leucine Rich Repeat Phage_T4_Gp30_7 PF06919.11 OWF35242.1 - 0.077 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Phage Gp30.7 protein F-box-like PF12937.7 OWF35242.1 - 0.13 12.2 3.3 0.34 10.8 0.1 2.7 2 1 0 2 2 2 0 F-box-like Lipase_GDSL_2 PF13472.6 OWF35243.1 - 1.3e-06 28.9 0.0 1.6e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF35243.1 - 0.00059 19.9 0.0 0.0011 19.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase A_deamin PF02137.18 OWF35244.1 - 1.3e-80 271.4 0.8 1.7e-80 270.9 0.8 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 OWF35244.1 - 0.059 14.1 0.1 0.16 12.7 0.1 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif A_deamin PF02137.18 OWF35245.1 - 6.5e-87 292.0 0.1 9.6e-87 291.5 0.1 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 OWF35245.1 - 1.1e-34 119.0 0.1 8.6e-11 42.4 0.0 3.6 3 0 0 3 3 3 3 Double-stranded RNA binding motif A_deamin PF02137.18 OWF35246.1 - 4.7e-88 295.8 0.1 7.4e-88 295.1 0.1 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 OWF35246.1 - 5.7e-30 103.8 0.8 4.2e-12 46.6 0.1 4.5 4 0 0 4 4 4 4 Double-stranded RNA binding motif PWWP PF00855.17 OWF35247.1 - 5.6e-13 49.1 16.7 9.1e-12 45.2 0.2 3.8 4 0 0 4 4 4 2 PWWP domain zf-C2HC_2 PF13913.6 OWF35248.1 - 7.5e-95 309.5 57.9 1.6e-10 40.6 0.9 10.4 10 0 0 10 10 10 10 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 OWF35248.1 - 8e-12 44.9 30.9 0.62 10.6 0.1 10.3 10 0 0 10 10 10 3 Zinc finger, C2H2 type c-SKI_SMAD_bind PF08782.10 OWF35248.1 - 1.3e-11 44.5 2.1 1 9.6 0.0 6.4 6 0 0 6 6 6 3 c-SKI Smad4 binding domain DUF2318 PF10080.9 OWF35248.1 - 2e-11 43.9 25.4 0.22 11.7 0.1 9.5 9 1 1 10 10 10 4 Predicted membrane protein (DUF2318) Rad50_zn_hook PF04423.14 OWF35248.1 - 5.1e-10 39.0 13.2 0.2 11.5 0.0 6.7 8 0 0 8 8 7 5 Rad50 zinc hook motif zf-RING_7 PF02591.15 OWF35248.1 - 3.9e-08 33.3 10.7 0.82 9.9 0.0 6.3 6 0 0 6 6 6 3 C4-type zinc ribbon domain zf-C2H2_4 PF13894.6 OWF35248.1 - 6.2e-08 32.8 41.0 7.9 7.6 0.2 10.7 11 0 0 11 11 10 2 C2H2-type zinc finger DUF1178 PF06676.11 OWF35248.1 - 6.3e-05 23.4 10.8 3.5 8.0 0.1 5.4 6 0 0 6 6 6 1 Protein of unknown function (DUF1178) zf_UBZ PF18439.1 OWF35248.1 - 0.0002 20.9 18.8 1.6 8.4 0.0 7.7 9 0 0 9 9 9 3 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 OWF35248.1 - 0.00023 20.6 35.3 2.1 8.0 0.1 9.7 10 0 0 10 10 10 3 Sgf11 (transcriptional regulation protein) Ribosomal_L32p PF01783.23 OWF35248.1 - 0.00042 20.5 7.5 4.2 7.7 0.1 5.8 5 0 0 5 5 5 1 Ribosomal L32p protein family zf-FPG_IleRS PF06827.14 OWF35248.1 - 0.00057 19.7 16.8 1.1 9.2 0.1 5.9 5 0 0 5 5 5 1 Zinc finger found in FPG and IleRS zf-dskA_traR PF01258.17 OWF35248.1 - 0.039 13.9 10.4 26 4.9 0.0 5.5 6 0 0 6 6 5 0 Prokaryotic dksA/traR C4-type zinc finger zf-BED PF02892.15 OWF35248.1 - 0.041 13.9 13.0 24 5.1 0.1 6.6 8 0 0 8 8 7 0 BED zinc finger zinc_ribbon_4 PF13717.6 OWF35248.1 - 0.064 13.2 27.3 42 4.2 0.1 10.2 12 0 0 12 12 12 0 zinc-ribbon domain DUF4428 PF14471.6 OWF35248.1 - 2 8.4 9.5 70 3.5 0.1 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4428) Pkinase PF00069.25 OWF35249.1 - 2.4e-71 240.2 2.1 1.1e-70 238.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35249.1 - 8.1e-47 159.7 0.3 4.1e-46 157.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase MIT PF04212.18 OWF35249.1 - 8.6e-30 102.6 7.4 1.8e-20 72.8 1.7 2.9 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Tma16 PF11176.8 OWF35249.1 - 0.0046 16.8 1.3 0.011 15.7 1.3 1.6 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Kdo PF06293.14 OWF35249.1 - 0.01 15.2 0.1 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF35249.1 - 0.039 13.3 0.1 0.18 11.1 0.0 2.1 2 1 0 2 2 2 0 Kinase-like ABC1 PF03109.16 OWF35249.1 - 0.042 14.0 1.0 0.11 12.6 0.1 2.2 2 1 1 3 3 3 0 ABC1 family SMBP PF16785.5 OWF35249.1 - 0.073 13.3 4.2 0.08 13.2 0.6 2.3 2 0 0 2 2 2 0 Small metal-binding protein Choline_kinase PF01633.20 OWF35249.1 - 0.087 12.4 5.1 0.16 11.5 0.0 3.0 3 1 1 4 4 4 0 Choline/ethanolamine kinase Uteroglobin PF01099.17 OWF35249.1 - 0.12 12.7 1.8 5 7.5 0.2 2.8 1 1 1 2 2 2 0 Uteroglobin family TSC22 PF01166.18 OWF35249.1 - 0.14 12.5 4.3 0.073 13.4 1.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family AAA_assoc_C PF09821.9 OWF35249.1 - 0.93 10.0 6.0 0.54 10.8 1.3 2.7 3 0 0 3 3 3 0 C-terminal AAA-associated domain DCP2 PF05026.13 OWF35250.1 - 2.7e-32 110.9 0.6 6.6e-32 109.7 0.6 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OWF35250.1 - 2.3e-18 66.5 0.0 4.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Orthopox_F6 PF06601.12 OWF35250.1 - 0.078 13.1 0.4 0.21 11.8 0.4 1.6 1 0 0 1 1 1 0 Orthopoxvirus F6 protein Neugrin PF06413.11 OWF35251.1 - 1.4e-14 54.7 0.7 1.4e-14 54.7 0.7 2.2 2 2 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 OWF35251.1 - 0.032 14.4 0.7 0.032 14.4 0.7 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Type2_restr_D3 PF16902.5 OWF35253.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Pkinase_Tyr PF07714.17 OWF35254.1 - 8.9e-92 307.0 0.0 1.3e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF35254.1 - 2.6e-44 151.6 0.0 4.7e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 OWF35254.1 - 9.2e-15 54.5 0.0 6.8e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF35254.1 - 2.4e-12 47.3 2.9 2.4e-06 28.1 0.3 2.8 2 0 0 2 2 2 2 Immunoglobulin domain LRR_8 PF13855.6 OWF35254.1 - 6.9e-09 35.3 1.3 3.2e-08 33.2 0.3 2.8 2 0 0 2 2 2 1 Leucine rich repeat Ig_2 PF13895.6 OWF35254.1 - 1.3e-05 25.5 1.3 0.073 13.4 0.1 3.1 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 OWF35254.1 - 0.002 18.1 0.1 0.26 11.4 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Shisa PF13908.6 OWF35254.1 - 0.089 13.0 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HSP70 PF00012.20 OWF35255.1 - 0.00013 20.3 0.1 0.00018 19.9 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 OWF35255.1 - 0.055 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HSP70 PF00012.20 OWF35256.1 - 2.4e-16 59.1 0.1 3.3e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF35256.1 - 0.0002 20.3 1.8 0.00046 19.1 0.4 2.1 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OWF35256.1 - 0.0004 20.7 0.0 0.00086 19.7 0.0 1.7 1 0 0 1 1 1 1 Cell division protein FtsA StbA PF06406.11 OWF35256.1 - 0.035 13.3 0.9 13 4.9 0.0 3.3 3 0 0 3 3 3 0 StbA protein DDR PF08841.10 OWF35256.1 - 0.1 11.6 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 OWF35257.1 - 8.3e-15 54.0 0.0 1.4e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein DDR PF08841.10 OWF35257.1 - 0.015 14.3 0.8 2.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 OWF35257.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MukB PF04310.12 OWF35257.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal FGGY_C PF02782.16 OWF35257.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain VWA_2 PF13519.6 OWF35258.1 - 1.5e-11 44.9 0.1 5.7e-11 43.0 0.1 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain MIB_HERC2 PF06701.13 OWF35258.1 - 5.2e-10 39.4 2.7 5.2e-10 39.4 2.7 2.0 2 0 0 2 2 2 1 Mib_herc2 WWE PF02825.20 OWF35258.1 - 1.1e-07 32.4 3.6 2.4e-07 31.2 3.6 1.6 1 0 0 1 1 1 1 WWE domain VWA PF00092.28 OWF35258.1 - 6.9e-06 26.4 0.1 1.5e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Lipase_chap PF03280.14 OWF35258.1 - 1.6 8.7 4.8 0.86 9.5 1.0 2.3 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein Mucin PF01456.17 OWF35258.1 - 2 8.4 19.3 4.5 7.3 19.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 OWF35258.1 - 4.8 5.3 10.8 7.1 4.7 10.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA PF00004.29 OWF35260.1 - 3.9e-36 124.4 0.0 1e-35 123.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF35260.1 - 1.7e-10 40.5 0.2 7.2e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 OWF35260.1 - 6.6e-05 22.7 0.0 0.00042 20.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain LisH PF08513.11 OWF35260.1 - 0.00021 21.1 0.3 0.00042 20.2 0.3 1.5 1 0 0 1 1 1 1 LisH TIP49 PF06068.13 OWF35260.1 - 0.00044 19.6 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 OWF35260.1 - 0.002 18.4 0.1 0.014 15.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OWF35260.1 - 0.002 18.1 0.0 0.0065 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OWF35260.1 - 0.0028 17.4 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 OWF35260.1 - 0.004 17.6 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 OWF35260.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OWF35260.1 - 0.0088 16.4 0.0 0.048 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 OWF35260.1 - 0.015 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 OWF35260.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OWF35260.1 - 0.024 15.2 0.1 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OWF35260.1 - 0.027 14.2 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF35260.1 - 0.038 14.1 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OWF35260.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 OWF35260.1 - 0.067 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 OWF35260.1 - 0.076 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 OWF35260.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OWF35260.1 - 0.086 12.5 0.0 1.1 8.9 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain TsaE PF02367.17 OWF35260.1 - 0.087 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OWF35260.1 - 0.091 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 OWF35260.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Spaetzle PF16077.5 OWF35261.1 - 0.039 14.5 0.6 0.086 13.4 0.6 1.6 1 0 0 1 1 1 0 Spaetzle Arrestin_N PF00339.29 OWF35262.1 - 3.9e-23 82.1 0.0 3.3e-22 79.1 0.0 2.2 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF35262.1 - 3.9e-13 50.0 0.0 1.3e-12 48.3 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 OWF35262.1 - 0.13 11.4 0.0 3.9 6.5 0.0 2.4 3 0 0 3 3 3 0 Rgp1 Bcl-2 PF00452.19 OWF35263.1 - 3.3e-25 88.6 0.0 4.9e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Cu2_monoox_C PF03712.15 OWF35265.1 - 2.8e-38 130.9 0.0 5.8e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain NHL PF01436.21 OWF35265.1 - 5.7e-26 89.2 8.1 9e-07 28.6 0.0 5.6 5 0 0 5 5 5 4 NHL repeat Cu2_monooxygen PF01082.20 OWF35265.1 - 4.1e-24 85.3 0.1 8.2e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Lactonase PF10282.9 OWF35265.1 - 0.0049 16.2 0.1 2.4 7.3 0.0 3.1 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller TMEM154 PF15102.6 OWF35265.1 - 0.0055 16.6 2.3 0.019 14.9 0.2 2.2 2 0 0 2 2 2 1 TMEM154 protein family SGL PF08450.12 OWF35265.1 - 0.011 15.4 0.2 10 5.6 0.0 3.4 1 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Podoplanin PF05808.11 OWF35265.1 - 0.069 13.3 2.7 0.15 12.2 2.7 1.5 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.20 OWF35265.1 - 0.15 12.0 0.8 0.3 11.0 0.8 1.5 1 0 0 1 1 1 0 Syndecan domain ECSCR PF15820.5 OWF35265.1 - 0.43 10.4 1.7 1.4 8.8 0.4 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4519 PF15012.6 OWF35265.1 - 7 6.9 7.6 18 5.6 7.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Asparaginase_2 PF01112.18 OWF35266.1 - 1.1e-57 195.5 4.0 3.9e-31 108.2 0.2 2.0 1 1 1 2 2 2 2 Asparaginase CheC PF04509.12 OWF35266.1 - 0.033 14.1 1.4 0.042 13.7 0.1 1.8 2 0 0 2 2 2 0 CheC-like family Mab-21 PF03281.14 OWF35267.1 - 2.5e-30 105.8 1.0 4.5e-30 104.9 1.0 1.4 1 0 0 1 1 1 1 Mab-21 protein Zip PF02535.22 OWF35268.1 - 1.8e-58 198.4 8.2 2.4e-58 197.9 8.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1194 PF06707.11 OWF35268.1 - 0.12 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Zip PF02535.22 OWF35269.1 - 1.8e-50 172.1 13.8 3.3e-50 171.2 13.8 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1194 PF06707.11 OWF35269.1 - 0.074 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) GvpH PF05455.11 OWF35269.1 - 0.24 11.5 3.6 0.06 13.4 0.6 1.5 2 0 0 2 2 2 0 GvpH Flp1_like PF16982.5 OWF35270.1 - 9.9 5.6 7.8 19 4.7 7.8 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Peptidase_A22B PF04258.13 OWF35271.1 - 5.5e-73 245.9 11.9 8.4e-73 245.4 11.9 1.2 1 0 0 1 1 1 1 Signal peptide peptidase Connexin PF00029.19 OWF35271.1 - 1.3e-05 25.1 0.5 4.7e-05 23.3 0.4 1.7 1 1 0 1 1 1 1 Connexin PA PF02225.22 OWF35271.1 - 0.0033 17.4 0.0 0.01 15.8 0.0 1.9 1 0 0 1 1 1 1 PA domain FAM176 PF14851.6 OWF35271.1 - 0.023 14.4 1.7 0.089 12.5 0.0 2.4 2 1 0 2 2 2 0 FAM176 family Orf78 PF06024.12 OWF35271.1 - 0.032 14.5 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Orf78 (ac78) PRC2_HTH_1 PF18118.1 OWF35271.1 - 0.037 14.8 1.1 0.075 13.8 1.1 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain AP3D1 PF06375.11 OWF35271.1 - 0.38 11.0 7.8 0.72 10.1 7.8 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Adeno_PV PF03910.13 OWF35271.1 - 4.5 5.9 7.9 0.27 9.9 2.5 1.6 2 0 0 2 2 2 0 Adenovirus minor core protein PV LRR_6 PF13516.6 OWF35272.1 - 0.00011 22.0 20.7 38 4.7 0.1 10.7 11 0 0 11 11 11 3 Leucine Rich repeat Mei5_like PF17021.5 OWF35272.1 - 0.021 14.9 0.8 0.062 13.3 0.8 1.8 1 0 0 1 1 1 0 Putative double-strand recombination repair-like LRR_4 PF12799.7 OWF35272.1 - 0.057 13.9 26.9 3 8.4 0.0 7.5 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) COX4_pro_2 PF07835.12 OWF35273.1 - 0.0035 17.4 0.0 0.0074 16.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial aa3 type cytochrome c oxidase subunit IV DPPIV_N PF00930.21 OWF35274.1 - 8.4e-73 245.1 0.7 1.3e-72 244.5 0.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OWF35274.1 - 2.6e-57 193.7 0.1 4.7e-57 192.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OWF35274.1 - 2.5e-13 50.3 0.1 1.3e-12 47.9 0.1 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OWF35274.1 - 7.9e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 OWF35274.1 - 1.6e-05 25.6 0.1 3.6e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF35274.1 - 2.4e-05 23.7 0.7 0.00042 19.6 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 OWF35274.1 - 0.00074 19.1 0.1 0.0087 15.6 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OWF35274.1 - 0.008 15.8 0.4 0.016 14.8 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 OWF35274.1 - 0.015 14.0 0.1 0.36 9.5 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 OWF35274.1 - 0.038 13.8 0.1 3.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OWF35274.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_32 PF13679.6 OWF35275.1 - 1.3e-22 80.5 11.3 8.3e-11 42.1 5.3 2.3 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 OWF35275.1 - 0.0066 16.2 0.1 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 OWF35275.1 - 0.042 14.5 0.0 0.2 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 OWF35275.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Helicase_C PF00271.31 OWF35276.1 - 6.2e-17 61.9 0.0 1.5e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF35276.1 - 1.1e-05 25.2 0.0 5.6e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.6 OWF35276.1 - 0.072 13.3 0.1 1.4 9.1 0.0 2.2 1 1 1 2 2 2 0 Helicase C-terminal domain Ribosomal_L19 PF01245.20 OWF35278.1 - 0.0016 18.3 0.1 0.0039 17.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 Mrpl_C PF18502.1 OWF35279.1 - 0.43 10.9 4.7 4.8 7.5 0.1 2.5 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain RRF PF01765.19 OWF35279.1 - 0.67 9.9 6.9 0.47 10.4 0.2 2.5 2 1 0 2 2 2 0 Ribosome recycling factor Neur_chan_LBD PF02931.23 OWF35281.1 - 3.9e-33 114.7 0.4 6.4e-33 114.0 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF35281.1 - 8.1e-19 68.6 10.8 1.8e-18 67.5 10.8 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Tmpp129 PF10272.9 OWF35281.1 - 0.095 12.0 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF21 PF01595.20 OWF35281.1 - 0.17 11.6 3.3 0.15 11.7 1.1 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Neur_chan_LBD PF02931.23 OWF35282.1 - 2.3e-24 86.1 0.9 2.8e-24 85.8 0.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Glyco_transf_29 PF00777.18 OWF35282.1 - 0.021 14.2 0.1 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) Neur_chan_LBD PF02931.23 OWF35284.1 - 1.6e-09 37.5 1.4 2.8e-09 36.8 1.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF35284.1 - 5.2e-07 30.0 4.8 5.2e-07 30.0 4.8 2.3 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF5367 PF17329.2 OWF35284.1 - 0.6 10.3 7.1 0.037 14.2 1.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF4834 PF16118.5 OWF35284.1 - 1.1 10.3 5.1 1.4 9.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) JTB PF05439.12 OWF35284.1 - 2.7 8.1 5.7 5.2 7.2 0.2 3.0 3 0 0 3 3 3 0 Jumping translocation breakpoint protein (JTB) DHHC PF01529.20 OWF35284.1 - 3 8.0 13.3 1.9 8.6 0.8 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Hydrolase_4 PF12146.8 OWF35285.1 - 0.096 11.9 0.1 7.2 5.8 0.0 2.6 1 1 2 3 3 3 0 Serine aminopeptidase, S33 ShlB PF03865.13 OWF35285.1 - 0.37 10.2 0.6 15 4.9 0.3 2.2 1 1 1 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB CnrY PF17524.2 OWF35285.1 - 1.1 9.5 7.3 24 5.2 0.1 3.9 3 2 2 5 5 5 0 Anti-sigma factor CnrY Alpha_E3_glycop PF01563.16 OWF35285.1 - 2.3 8.4 12.2 17 5.6 0.1 4.8 1 1 5 6 6 6 0 Alphavirus E3 glycoprotein Neur_chan_LBD PF02931.23 OWF35286.1 - 6.7e-09 35.5 1.9 1.4e-08 34.4 1.9 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF35286.1 - 4.2e-06 27.0 4.0 4.2e-06 27.0 4.0 2.4 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region TMEM154 PF15102.6 OWF35287.1 - 0.0047 16.8 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 OWF35287.1 - 0.0071 16.6 0.0 0.011 16.0 0.0 1.3 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DcuC PF03606.15 OWF35287.1 - 0.016 13.7 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Vpu PF00558.19 OWF35287.1 - 0.019 14.8 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Vpu protein TMEM252 PF15664.5 OWF35287.1 - 0.022 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF1673 PF07895.11 OWF35287.1 - 0.048 13.4 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) TMEM51 PF15345.6 OWF35287.1 - 0.071 13.0 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Plasmodium_Vir PF05795.11 OWF35287.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EphA2_TM PF14575.6 OWF35287.1 - 0.16 12.8 0.1 0.33 11.9 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain C1q PF00386.21 OWF35288.1 - 5.3e-18 65.4 0.1 8.5e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 C1q domain ATG16 PF08614.11 OWF35288.1 - 0.0042 17.3 3.1 0.0074 16.5 3.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) MAD PF05557.13 OWF35288.1 - 0.011 14.2 0.4 0.013 13.9 0.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Xan_ur_permease PF00860.20 OWF35290.1 - 3.2e-53 180.8 8.0 3.2e-53 180.8 8.0 1.4 2 0 0 2 2 2 1 Permease family AAA_25 PF13481.6 OWF35290.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1943 PF09172.11 OWF35291.1 - 1.1 8.4 3.4 2 7.6 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) SspN PF08177.11 OWF35292.1 - 0.3 11.1 5.6 7.9 6.5 0.5 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein N family Alpha_L_fucos PF01120.17 OWF35293.1 - 1.7e-121 406.0 9.1 2.2e-121 405.6 9.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF35293.1 - 7.2e-26 90.6 0.0 1.4e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 OWF35293.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Pkinase PF00069.25 OWF35294.1 - 1.7e-74 250.6 0.0 6.3e-74 248.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35294.1 - 7.5e-39 133.6 0.0 9.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF35294.1 - 2.7e-06 26.9 0.0 8.3e-06 25.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OWF35294.1 - 4.5e-05 22.6 0.1 7.7e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OWF35294.1 - 5.3e-05 22.9 0.2 8.4e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OWF35294.1 - 0.00012 21.5 0.2 0.0002 20.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF35294.1 - 0.049 13.6 0.1 0.076 12.9 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OWF35294.1 - 0.073 12.7 0.4 0.62 9.6 0.2 2.5 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SUZ PF12752.7 OWF35294.1 - 0.56 11.0 4.4 4.8 8.0 0.1 3.1 3 0 0 3 3 3 0 SUZ domain WH1 PF00568.23 OWF35295.1 - 6.4e-35 119.5 0.1 8.9e-35 119.0 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 OWF35295.1 - 1.4e-15 57.4 0.3 3.3e-15 56.2 0.3 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 OWF35295.1 - 9.3e-12 44.4 0.9 3.9e-06 26.5 0.1 2.6 2 0 0 2 2 2 2 WH2 motif NOA36 PF06524.12 OWF35295.1 - 0.52 9.6 6.6 0.93 8.8 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein Beta_helix_2 PF18835.1 OWF35296.1 - 0.12 12.1 25.7 9.3 6.1 0.6 5.3 1 1 6 7 7 7 0 Beta helix repeat of Inulin fructotransferase MutS_V PF00488.21 OWF35296.1 - 0.22 11.5 10.5 0.85 9.6 0.6 3.0 1 1 3 4 4 4 0 MutS domain V HERV-K_env_2 PF13804.6 OWF35296.1 - 0.23 11.2 8.5 10 5.9 1.0 3.8 1 1 3 4 4 4 0 Retro-transcribing viruses envelope glycoprotein Sacchrp_dh_C PF16653.5 OWF35297.1 - 8.6e-86 288.3 0.0 1.4e-85 287.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 OWF35297.1 - 5.2e-24 85.0 0.1 2.6e-23 82.7 0.2 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 OWF35297.1 - 1.2e-18 67.8 1.2 8.9e-16 58.4 0.2 3.1 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 OWF35297.1 - 8.1e-13 48.2 0.1 2.6e-06 26.9 0.0 3.2 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 OWF35297.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OWF35297.1 - 0.019 14.9 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Kelch_1 PF01344.25 OWF35298.1 - 8.8e-57 188.5 0.9 1.6e-10 40.4 0.0 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 OWF35298.1 - 1.1e-44 149.3 1.5 3.3e-08 33.5 0.0 7.5 3 3 5 8 8 8 6 Kelch motif Kelch_4 PF13418.6 OWF35298.1 - 1.3e-40 137.1 0.1 6e-08 32.6 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF35298.1 - 4.1e-25 86.7 1.3 0.00028 20.7 0.0 7.3 6 1 1 7 7 7 6 Kelch motif Kelch_3 PF13415.6 OWF35298.1 - 2.7e-22 78.5 0.0 0.00093 19.4 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF35298.1 - 1.4e-14 53.7 3.3 0.013 15.5 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 OWF35299.1 - 7e-27 92.8 3.7 6e-08 32.2 0.0 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OWF35299.1 - 2.9e-24 84.5 1.3 3.6e-07 30.2 0.0 5.5 4 1 1 5 5 5 4 Kelch motif BTB PF00651.31 OWF35299.1 - 1e-22 80.5 0.2 2.7e-22 79.1 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 OWF35299.1 - 1.3e-17 63.0 1.2 9.3e-06 25.4 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OWF35299.1 - 4.8e-13 48.9 2.3 0.0002 21.3 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain BACK PF07707.15 OWF35299.1 - 9.4e-11 41.7 0.1 1.8e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 OWF35299.1 - 1.7e-10 40.9 5.4 0.011 16.0 0.0 4.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF35299.1 - 0.00052 19.9 4.2 3.8 7.6 0.0 4.5 4 0 0 4 4 4 2 Kelch motif BTB_3 PF16017.5 OWF35299.1 - 0.0041 17.2 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF4598 PF15370.6 OWF35300.1 - 2.2e-10 41.0 0.9 2.2e-10 41.0 0.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Vps53_N PF04100.12 OWF35300.1 - 0.23 10.4 1.3 1.7 7.5 0.1 2.0 2 0 0 2 2 2 0 Vps53-like, N-terminal MgtE PF01769.16 OWF35301.1 - 7.2e-51 171.8 27.9 8.8e-27 93.9 5.1 3.2 3 0 0 3 3 3 2 Divalent cation transporter Mon1 PF03164.14 OWF35302.1 - 6.2e-147 489.9 4.8 7.2e-147 489.7 4.8 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Metallophos PF00149.28 OWF35303.1 - 1.2e-21 78.2 1.2 2e-21 77.4 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OWF35303.1 - 8.2e-15 55.2 0.0 1.2e-13 51.5 0.0 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OWF35303.1 - 4.2e-10 40.3 0.1 1.2e-09 38.9 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 OWF35303.1 - 3.1e-05 24.2 0.1 0.00015 22.0 0.1 2.0 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PUB PF09409.10 OWF35304.1 - 2.7e-21 75.3 0.1 5.2e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 OWF35304.1 - 6.2e-08 32.7 0.3 5e-07 29.8 0.0 2.6 3 0 0 3 3 3 1 UBX domain RNase_E_G PF10150.9 OWF35304.1 - 0.032 13.7 1.1 0.049 13.0 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease E/G family UPF0242 PF06785.11 OWF35304.1 - 1.3 9.1 6.6 0.35 10.9 1.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4_2 PF13923.6 OWF35305.1 - 1.9e-11 43.6 10.8 1.9e-11 43.6 10.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OWF35305.1 - 9.5e-10 38.2 2.7 9.5e-10 38.2 2.7 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 OWF35305.1 - 5.5e-08 32.6 11.6 5.5e-08 32.6 11.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF35305.1 - 5.3e-07 29.4 8.0 5.3e-07 29.4 8.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF35305.1 - 8e-07 28.9 10.3 8e-07 28.9 10.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF35305.1 - 2.6e-06 27.7 10.0 2.6e-06 27.7 10.0 2.4 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.27 OWF35305.1 - 3.7e-06 26.5 0.1 7.6e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-rbx1 PF12678.7 OWF35305.1 - 5.6e-05 23.3 5.9 5.6e-05 23.3 5.9 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF35305.1 - 8.2e-05 22.6 10.4 8.2e-05 22.6 10.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-CpG_bind_C PF12269.8 OWF35305.1 - 0.00023 21.0 0.1 0.00023 21.0 0.1 2.6 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain zf-RING_10 PF16685.5 OWF35305.1 - 0.0062 16.6 6.3 0.016 15.3 6.3 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Di19 PF05605.12 OWF35305.1 - 0.032 14.5 11.7 0.97 9.8 6.4 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 OWF35305.1 - 0.064 13.1 11.1 0.32 10.9 8.7 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OWF35305.1 - 0.091 12.8 3.0 0.33 11.0 3.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OWF35305.1 - 0.2 11.8 16.3 0.044 13.9 11.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OWF35305.1 - 0.85 9.5 10.2 0.17 11.7 5.8 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 OWF35305.1 - 4 7.5 9.7 3.9 7.6 5.5 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 OWF35305.1 - 5.9 6.8 11.8 1.3 8.8 7.7 2.1 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OWF35305.1 - 7.3 6.4 8.8 19 5.1 8.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger AKNA PF12443.8 OWF35306.1 - 6.1e-07 30.0 25.0 4.9 7.9 0.2 8.0 1 1 9 10 10 10 8 AT-hook-containing transcription factor IF2_N PF04760.15 OWF35306.1 - 9e-05 22.2 17.7 39 4.2 0.1 8.9 1 1 9 10 10 10 0 Translation initiation factor IF-2, N-terminal region HTH_Tnp_Mu_2 PF09039.11 OWF35306.1 - 0.084 13.0 3.5 46 4.1 0.2 4.2 1 1 5 6 6 6 0 Mu DNA binding, I gamma subdomain HBD PF18534.1 OWF35306.1 - 0.56 10.4 15.9 27 5.0 0.2 5.0 1 1 7 8 8 8 0 Helical bundle domain Mt_ATP_synt PF15704.5 OWF35306.1 - 4.7 7.1 27.3 8.1 6.3 2.1 4.1 1 1 2 4 4 4 0 Mitochondrial ATP synthase subunit UvrD-helicase PF00580.21 OWF35307.1 - 1.5e-12 47.6 0.4 2.6e-09 37.1 0.2 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OWF35307.1 - 8e-12 45.2 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OWF35307.1 - 4.6e-11 43.3 0.0 9.5e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OWF35307.1 - 1.4e-09 37.7 0.2 4.1e-09 36.1 0.2 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain F-box PF00646.33 OWF35307.1 - 8.3e-09 35.1 1.1 2.3e-08 33.7 1.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OWF35307.1 - 1.2e-08 34.7 0.2 3.9e-08 33.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like Viral_helicase1 PF01443.18 OWF35307.1 - 3.3e-06 27.0 2.5 0.37 10.5 0.0 3.7 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OWF35307.1 - 1.7e-05 24.6 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 OWF35307.1 - 0.0012 18.8 0.1 0.0041 17.1 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF35307.1 - 0.0055 17.0 0.1 0.6 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OWF35307.1 - 0.056 12.9 0.1 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 OWF35307.1 - 0.15 11.9 0.5 13 5.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Ras PF00071.22 OWF35308.1 - 6.1e-49 165.7 0.8 7.7e-49 165.4 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF35308.1 - 8.6e-14 51.8 0.1 1.6e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF35308.1 - 3.4e-05 23.4 0.2 4e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF35308.1 - 7.3e-05 22.4 0.2 0.00011 21.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF35308.1 - 0.0041 17.0 0.0 0.0074 16.2 0.0 1.4 1 1 0 1 1 1 1 RsgA GTPase zf-PARP PF00645.18 OWF35309.1 - 2.5e-08 34.6 1.6 7.4e-08 33.2 1.6 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PC4 PF02229.16 OWF35309.1 - 3.4e-05 23.4 2.6 0.00059 19.4 0.4 2.4 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) Tho1_MOS11_C PF18592.1 OWF35310.1 - 0.00014 21.6 7.3 0.75 9.6 0.1 4.2 1 1 5 6 6 6 5 Tho1/MOS11 C-terminal domain PG_binding_1 PF01471.18 OWF35310.1 - 0.0044 17.2 7.2 27 5.1 0.0 5.4 3 1 1 4 4 4 0 Putative peptidoglycan binding domain Pentapeptide_4 PF13599.6 OWF35310.1 - 0.0098 16.0 0.3 0.32 11.2 0.1 2.0 1 1 0 2 2 2 1 Pentapeptide repeats (9 copies) NPV_P10 PF05531.12 OWF35310.1 - 0.14 12.6 10.6 85 3.7 10.6 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein REV1_C PF16727.5 OWF35310.1 - 0.27 11.7 3.7 30 5.1 3.7 2.7 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain DUF5581 PF17744.1 OWF35310.1 - 0.59 9.4 15.1 4.2 6.6 0.6 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5581) DUF724 PF05266.14 OWF35310.1 - 0.61 9.9 6.5 1.6 8.5 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 OWF35310.1 - 1 8.8 7.4 1.2 8.7 7.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HTH_51 PF18558.1 OWF35310.1 - 2 8.4 7.2 16 5.5 0.6 2.7 1 1 2 3 3 3 0 Helix-turn-helix domain Peptidase_S37 PF05576.11 OWF35310.1 - 2.5 6.7 5.0 26 3.3 0.2 3.0 1 1 2 3 3 3 0 PS-10 peptidase S37 Shikimate_DH PF01488.20 OWF35310.1 - 7 6.7 8.7 11 6.1 2.5 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Axin_b-cat_bind PF08833.10 OWF35311.1 - 3.5 7.8 19.5 1.6e+02 2.5 0.1 9.2 7 3 3 10 10 10 0 Axin beta-catenin binding domain PDZ PF00595.24 OWF35312.1 - 2.6e-26 91.8 1.9 3.3e-15 56.2 0.5 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OWF35312.1 - 5.9e-19 67.7 0.3 1.6e-09 37.5 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OWF35312.1 - 2.3e-15 56.6 0.6 1.1e-08 35.2 0.8 2.6 2 0 0 2 2 2 2 PDZ domain zf-C3HC4_2 PF13923.6 OWF35312.1 - 1e-08 34.9 9.3 1e-08 34.9 9.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF35312.1 - 8e-06 25.6 7.9 8e-06 25.6 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF35312.1 - 3.6e-05 23.7 8.5 3.6e-05 23.7 8.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF35312.1 - 4.5e-05 23.7 9.5 4.5e-05 23.7 9.5 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF35312.1 - 5e-05 23.1 6.4 0.00013 21.8 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 OWF35312.1 - 5e-05 23.3 2.9 5e-05 23.3 2.9 2.0 1 1 1 2 2 2 1 Seven in absentia protein family zf-C3HC4_4 PF15227.6 OWF35312.1 - 0.00026 21.1 7.8 0.00026 21.1 7.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OWF35312.1 - 0.0012 19.1 5.6 0.0052 17.0 5.6 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-TRAF PF02176.18 OWF35312.1 - 0.0088 16.7 11.7 0.2 12.4 6.3 2.7 1 1 1 2 2 2 2 TRAF-type zinc finger Tricorn_PDZ PF14685.6 OWF35312.1 - 0.014 15.4 0.3 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain Prok-RING_4 PF14447.6 OWF35312.1 - 0.31 10.9 8.1 0.73 9.7 8.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF16 PF01519.16 OWF35312.1 - 6.9 7.2 9.1 60 4.2 2.7 3.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 L51_S25_CI-B8 PF05047.16 OWF35313.1 - 0.0012 18.8 10.0 70 3.5 0.1 8.7 4 3 2 6 6 6 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SLD5_C PF16922.5 OWF35313.1 - 0.0045 17.1 5.5 16 5.7 0.1 7.7 3 3 2 5 5 5 1 DNA replication complex GINS protein SLD5 C-terminus DUF1505 PF07403.11 OWF35313.1 - 5.3 7.2 36.7 24 5.1 3.8 7.4 1 1 6 7 7 7 0 Protein of unknown function (DUF1505) Apo-CII PF05355.11 OWF35314.1 - 2.2e-13 50.2 6.3 2.7 8.2 0.0 7.3 7 0 0 7 7 7 7 Apolipoprotein C-II DUF4685 PF15737.5 OWF35314.1 - 0.011 16.1 0.0 1.8e+02 2.5 0.0 5.5 7 0 0 7 7 7 0 Domain of unknown function (DUF4685) Sod_Fe_C PF02777.18 OWF35314.1 - 0.057 13.6 10.1 45 4.3 0.1 6.6 1 1 7 8 8 8 0 Iron/manganese superoxide dismutases, C-terminal domain DUF5362 PF17319.2 OWF35314.1 - 0.066 13.0 0.0 1.2e+02 2.6 0.0 5.2 8 0 0 8 8 8 0 Family of unknown function (DUF5362) DUF2804 PF10974.8 OWF35314.1 - 2 7.9 4.7 1.6e+02 1.6 0.0 4.6 1 1 5 6 6 6 0 Protein of unknown function (DUF2804) Toxin_7 PF05980.12 OWF35314.1 - 2.1 8.6 28.2 74 3.7 0.2 7.0 7 0 0 7 7 7 0 Toxin 7 Actin PF00022.19 OWF35315.1 - 3.3e-59 200.5 1.5 1.5e-58 198.4 0.0 2.7 2 1 0 2 2 2 1 Actin PH PF00169.29 OWF35315.1 - 0.00086 19.8 0.0 0.0047 17.4 0.0 2.3 1 0 0 1 1 1 1 PH domain CENP-Q PF13094.6 OWF35315.1 - 0.0014 18.9 0.7 0.0049 17.1 0.7 1.9 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit ZapB PF06005.12 OWF35315.1 - 0.12 12.8 5.1 0.3 11.6 5.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB PPP4R2 PF09184.11 OWF35316.1 - 1.1e-52 179.4 57.6 3.9e-52 177.6 29.1 2.9 1 1 1 2 2 2 1 PPP4R2 SPRY PF00622.28 OWF35317.1 - 3.4e-24 85.3 0.1 6.6e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 SPRY domain HAD PF12710.7 OWF35317.1 - 2.5e-10 41.1 0.0 5.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OWF35317.1 - 1.2e-08 35.5 0.0 3.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 OWF35317.1 - 3e-08 33.4 6.4 3e-08 33.4 6.4 2.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF35317.1 - 0.0013 18.5 9.7 0.0057 16.5 9.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF35317.1 - 0.014 15.4 9.7 0.039 14.0 9.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger UMPH-1 PF05822.12 OWF35317.1 - 0.026 14.1 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) AATF-Che1 PF13339.6 OWF35317.1 - 0.052 14.2 0.8 5.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor zf-RING_5 PF14634.6 OWF35317.1 - 0.12 12.4 16.2 0.012 15.5 9.7 2.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF35317.1 - 0.55 10.1 16.7 0.026 14.4 10.2 2.4 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF35317.1 - 1.1 9.2 16.9 0.18 11.7 10.0 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OWF35317.1 - 2 8.6 11.1 1.1 9.5 7.2 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 OWF35317.1 - 3 8.3 17.0 0.057 13.8 8.9 2.5 2 0 0 2 2 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 OWF35317.1 - 3.2 8.0 9.6 9.5 6.5 9.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING XLF PF09302.11 OWF35318.1 - 5.4e-36 124.4 0.3 9.5e-36 123.6 0.3 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component GGACT PF06094.12 OWF35319.1 - 2e-26 93.0 0.0 3e-15 56.9 0.0 2.1 1 1 1 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 OWF35319.1 - 3e-09 37.1 0.0 6.9e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 AIG2-like family Atypical_Card PF18461.1 OWF35319.1 - 0.0056 16.9 0.0 0.017 15.3 0.1 1.7 2 0 0 2 2 2 1 Atypical caspase recruitment domain hnRNP_Q_AcD PF18360.1 OWF35319.1 - 0.053 13.5 0.1 8 6.5 0.0 2.3 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Vac_Fusion PF02346.16 OWF35319.1 - 0.099 12.3 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 ZinT PF09223.11 OWF35319.1 - 0.13 12.1 0.0 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment GGACT PF06094.12 OWF35320.1 - 1.4e-22 80.6 0.0 1.7e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 OWF35320.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 AIG2-like family SOCS_box PF07525.16 OWF35321.1 - 7.9e-05 22.9 5.6 0.00035 20.9 3.0 3.0 2 1 1 3 3 3 1 SOCS box Glyco_transf_92 PF01697.27 OWF35322.1 - 1.1e-12 48.2 0.9 5e-12 46.0 0.9 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OWF35322.1 - 0.00051 20.5 0.1 0.0017 18.8 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF5314 PF17241.2 OWF35322.1 - 0.014 15.1 0.4 0.059 13.0 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5314) DUF1897 PF09005.10 OWF35322.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) Exo_endo_phos PF03372.23 OWF35323.1 - 2.6e-05 23.9 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MVP_shoulder PF11978.8 OWF35323.1 - 0.019 14.9 0.1 0.35 10.9 0.1 2.4 1 1 1 2 2 2 0 Shoulder domain Ank_2 PF12796.7 OWF35324.1 - 1.9e-33 114.9 2.1 9.4e-12 45.4 0.1 4.9 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35324.1 - 5.7e-32 109.7 0.4 2.5e-10 40.7 0.0 6.1 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF35324.1 - 6e-28 96.0 3.4 0.00043 20.6 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OWF35324.1 - 1e-27 93.1 0.5 0.0004 20.6 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OWF35324.1 - 7.6e-26 89.8 3.5 1.1e-09 38.3 0.1 6.1 5 1 1 6 6 6 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF35324.1 - 1.3e-07 31.8 1.9 3.8e-07 30.4 1.9 1.8 1 0 0 1 1 1 1 SOCS box RRM_1 PF00076.22 OWF35326.1 - 4.5e-33 112.9 1.2 8.8e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF35326.1 - 5.6e-11 42.4 0.8 4.4e-05 23.5 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OWF35326.1 - 0.00036 20.1 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF35326.1 - 0.0011 19.0 0.6 0.018 15.1 0.3 2.3 2 0 0 2 2 2 1 RNA binding motif Chromo_shadow PF01393.19 OWF35327.1 - 9.1e-30 102.5 0.0 1.7e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.24 OWF35327.1 - 2.4e-08 33.7 0.1 5.4e-05 23.0 0.2 2.7 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S49_N PF08496.10 OWF35327.1 - 0.064 13.3 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Chromo_shadow PF01393.19 OWF35328.1 - 8.8e-30 102.6 0.0 1.7e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.24 OWF35328.1 - 2.3e-08 33.8 0.1 5.2e-05 23.1 0.2 2.7 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S49_N PF08496.10 OWF35328.1 - 0.035 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nebulin PF00880.18 OWF35329.1 - 1.5e-14 53.5 0.3 4.2e-09 36.1 0.1 2.5 2 0 0 2 2 2 2 Nebulin repeat LIM PF00412.22 OWF35329.1 - 4.5e-12 46.0 8.2 8.7e-12 45.1 8.2 1.5 1 0 0 1 1 1 1 LIM domain Epimerase PF01370.21 OWF35330.1 - 7e-16 58.4 0.0 2.1e-14 53.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF35330.1 - 2.4e-05 23.9 0.1 0.033 13.6 0.0 2.8 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OWF35330.1 - 0.0003 20.0 0.0 0.0014 17.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 OWF35330.1 - 0.01 14.9 0.0 0.09 11.9 0.0 2.3 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 OWF35330.1 - 0.085 12.3 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Ig_3 PF13927.6 OWF35331.1 - 1.9e-35 121.3 1.4 4.5e-13 49.6 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF35331.1 - 1.1e-29 102.3 0.5 9e-09 35.3 0.0 4.1 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF35331.1 - 1.7e-25 89.1 3.5 1.4e-11 44.5 0.0 4.3 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 OWF35331.1 - 7.8e-22 77.3 1.4 3.3e-07 30.4 0.2 3.8 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF35331.1 - 1.2e-18 67.2 4.0 4.5e-07 30.0 0.1 4.5 3 2 1 4 4 4 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF35331.1 - 1.2e-05 25.2 0.1 0.44 10.6 0.0 4.1 3 1 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 OWF35331.1 - 6.3e-05 23.0 0.1 0.021 14.9 0.0 3.3 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 OWF35331.1 - 6.7e-05 23.1 0.1 0.11 12.8 0.0 4.0 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 OWF35331.1 - 8.3e-05 22.9 0.0 0.016 15.6 0.0 3.5 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain NEMP PF10225.9 OWF35332.1 - 3.2e-51 174.4 3.2 3.6e-51 174.2 3.2 1.0 1 0 0 1 1 1 1 NEMP family Peptidase_M18 PF02127.15 OWF35333.1 - 1.7e-176 587.3 0.0 2e-176 587.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OWF35333.1 - 1.1e-07 31.3 0.1 1.2e-06 27.8 0.1 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase NEMP PF10225.9 OWF35334.1 - 1.4e-74 250.9 12.1 1.9e-74 250.5 12.1 1.2 1 0 0 1 1 1 1 NEMP family Rnf-Nqr PF02508.14 OWF35334.1 - 0.081 12.9 4.1 0.11 12.5 3.4 1.5 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein DUF998 PF06197.13 OWF35334.1 - 0.21 11.2 5.3 0.76 9.3 5.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF998) RNase_H PF00075.24 OWF35334.1 - 1.9 8.6 4.7 2.1 8.5 0.6 2.4 2 1 1 3 3 3 0 RNase H Lactamase_B_2 PF12706.7 OWF35335.1 - 9.7e-15 54.6 0.0 6.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF35335.1 - 5.9e-09 36.2 0.0 3e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 OWF35335.1 - 9.1e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease zf-C3Hc3H PF13891.6 OWF35336.1 - 1.3e-30 105.5 20.1 2.1e-16 60.0 6.9 2.6 3 0 0 3 3 3 2 Potential DNA-binding domain WRC PF08879.10 OWF35336.1 - 0.81 9.4 8.3 4.1 7.2 0.3 3.7 3 0 0 3 3 3 0 WRC Cyclin_N PF00134.23 OWF35337.1 - 9.2e-23 80.4 2.0 4.2e-17 62.1 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain RUN PF02759.19 OWF35338.1 - 1.4e-23 83.4 0.3 3.2e-23 82.2 0.3 1.7 1 0 0 1 1 1 1 RUN domain BTB PF00651.31 OWF35339.1 - 2.2e-32 111.6 1.4 5.7e-32 110.3 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 OWF35339.1 - 3.6e-08 33.5 0.1 1.4e-07 31.6 0.2 1.9 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 OWF35339.1 - 0.00046 20.3 0.7 0.037 14.1 0.0 3.5 4 0 0 4 4 4 1 BTB And C-terminal Kelch PLAT PF01477.23 OWF35340.1 - 0.0033 18.0 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 PLAT/LH2 domain Homeodomain PF00046.29 OWF35342.1 - 3.4e-22 78.0 7.8 5.6e-22 77.4 7.8 1.4 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 OWF35342.1 - 0.00065 19.4 0.4 0.0016 18.2 0.4 1.6 1 0 0 1 1 1 1 QLQ EBV-NA3 PF05009.12 OWF35342.1 - 0.16 11.5 1.6 0.25 10.8 1.6 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NOA36 PF06524.12 OWF35342.1 - 0.27 10.5 5.9 0.36 10.1 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Collagen PF01391.18 OWF35343.1 - 2.3e-163 530.1 648.2 5.2e-09 35.7 31.7 21.3 2 1 15 17 17 17 14 Collagen triple helix repeat (20 copies) COLFI PF01410.18 OWF35343.1 - 2.3e-45 154.7 0.3 3.4e-45 154.1 0.3 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 OWF35343.1 - 0.063 13.6 3.4 0.11 12.9 3.4 1.3 1 0 0 1 1 1 0 von Willebrand factor type C domain Pyridoxal_deC PF00282.19 OWF35344.1 - 2.6e-103 345.7 0.0 3.1e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OWF35344.1 - 1e-08 34.8 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OWF35344.1 - 0.00036 19.6 0.1 0.0016 17.5 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 OWF35344.1 - 0.0021 16.8 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain SepSecS PF05889.13 OWF35344.1 - 0.0023 16.7 0.0 0.0041 15.9 0.0 1.4 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 OWF35344.1 - 0.16 11.1 0.0 0.43 9.7 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II Collagen PF01391.18 OWF35345.1 - 6.7e-145 471.0 652.5 1.4e-08 34.3 35.1 20.2 2 2 10 12 12 12 7 Collagen triple helix repeat (20 copies) COLFI PF01410.18 OWF35345.1 - 1.4e-30 106.4 0.2 2.9e-30 105.3 0.2 1.4 1 1 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 OWF35345.1 - 0.059 13.7 11.0 0.091 13.1 11.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type C domain TCR PF03638.15 OWF35345.1 - 0.89 9.9 6.3 1.6 9.1 6.3 1.4 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Nas2_N PF18265.1 OWF35346.1 - 2.1e-33 114.1 0.6 3.3e-33 113.4 0.6 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 OWF35346.1 - 1.4e-07 31.2 0.0 3.6e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 OWF35346.1 - 0.00011 22.5 0.1 0.00021 21.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF35346.1 - 0.0013 19.0 0.1 0.0023 18.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Sushi PF00084.20 OWF35347.1 - 2.3e-15 56.9 14.1 8e-09 36.0 3.4 3.6 3 1 0 3 3 3 3 Sushi repeat (SCR repeat) PAN_1 PF00024.26 OWF35347.1 - 3e-06 27.1 0.2 9.6e-06 25.5 0.2 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 OWF35347.1 - 1.7e-05 24.8 0.7 5.4e-05 23.2 0.7 1.8 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 OWF35347.1 - 5.1e-05 23.1 1.7 5.1e-05 23.1 1.7 2.3 2 0 0 2 2 2 1 PAN domain F5_F8_type_C PF00754.25 OWF35348.1 - 3.1e-15 56.4 0.0 8.3e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Sushi PF00084.20 OWF35348.1 - 1.4e-05 25.5 0.3 6.1e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 Sushi repeat (SCR repeat) Ras PF00071.22 OWF35349.1 - 2.9e-44 150.5 0.0 5e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Ras family BTB PF00651.31 OWF35349.1 - 3.8e-38 130.1 0.7 4.1e-21 75.3 0.1 4.0 4 0 0 4 4 4 3 BTB/POZ domain Roc PF08477.13 OWF35349.1 - 2.7e-18 66.3 0.0 5.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF35349.1 - 2.3e-06 27.2 0.0 5.4e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family BACK PF07707.15 OWF35349.1 - 0.0034 17.4 0.1 0.3 11.2 0.0 3.0 3 0 0 3 3 3 1 BTB And C-terminal Kelch G-alpha PF00503.20 OWF35350.1 - 1.7e-34 119.5 3.9 1.9e-34 119.4 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit LPMO_10 PF03067.15 OWF35351.1 - 8.5e-17 62.4 0.7 1.1e-16 62.1 0.7 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 OWF35352.1 - 1.8e-38 133.2 0.6 2.4e-38 132.7 0.6 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Lectin_C PF00059.21 OWF35353.1 - 2.8e-11 44.1 2.8 3.8e-11 43.7 2.8 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF35353.1 - 0.01 15.5 0.3 0.01 15.5 0.3 2.5 3 0 0 3 3 3 1 UL45 protein, carbohydrate-binding C-type lectin-like AHSA1 PF08327.11 OWF35353.1 - 0.048 13.9 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein LPMO_10 PF03067.15 OWF35354.1 - 5.1e-23 82.7 1.7 1.1e-11 45.8 0.0 2.2 1 1 1 2 2 2 2 Lytic polysaccharide mono-oxygenase, cellulose-degrading Lectin_C PF00059.21 OWF35355.1 - 1.1e-15 58.3 1.4 1.4e-15 57.9 1.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF35355.1 - 0.0003 20.5 0.1 0.00083 19.0 0.0 1.7 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like C1q PF00386.21 OWF35356.1 - 1.8e-16 60.5 0.4 6.2e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF35356.1 - 1.5e-06 28.1 1.4 2.6e-06 27.4 1.4 1.3 1 0 0 1 1 1 1 BclA C-terminal domain HlyD_2 PF12700.7 OWF35356.1 - 0.004 15.9 4.0 0.0073 15.1 4.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein DUF641 PF04859.12 OWF35356.1 - 0.073 13.4 2.4 0.19 12.0 0.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 OWF35356.1 - 1.1 9.1 6.1 1.4 8.8 1.1 1.9 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GST_N_3 PF13417.6 OWF35357.1 - 4e-22 78.4 0.1 1.1e-21 77.0 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF35357.1 - 2.7e-17 62.9 0.0 6.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF35357.1 - 1.1e-14 54.4 0.0 2.3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF35357.1 - 3e-11 43.2 0.0 5.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF35357.1 - 8.9e-09 35.5 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF35357.1 - 2.1e-05 24.6 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OWF35357.1 - 0.00027 21.1 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Abhydrolase_3 PF07859.13 OWF35358.1 - 2.1e-53 181.3 0.0 8.2e-40 136.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OWF35358.1 - 1.7e-11 43.7 0.2 4.3e-10 39.1 0.0 2.6 2 1 0 2 2 2 1 Carboxylesterase family Say1_Mug180 PF10340.9 OWF35358.1 - 3.6e-05 22.8 0.0 4.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OWF35358.1 - 0.00091 18.8 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 OWF35358.1 - 0.012 14.3 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 OWF35358.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 OWF35358.1 - 0.19 11.8 0.0 0.63 10.1 0.0 1.9 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 OWF35358.1 - 0.19 10.6 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 OWF35358.1 - 0.2 11.2 0.2 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Putative esterase HipN PF18253.1 OWF35359.1 - 5.7e-12 45.1 3.9 5.8 6.7 0.0 15.1 13 8 9 22 22 22 1 Hsp70-interacting protein N N-terminal domain DUF956 PF06115.11 OWF35359.1 - 4.4e-11 42.5 5.8 4.5 7.0 0.1 8.7 2 2 7 11 11 11 3 Domain of unknown function (DUF956) DUF3106 PF11304.8 OWF35359.1 - 0.0015 19.0 0.0 27 5.3 0.0 3.3 1 1 0 2 2 2 1 Protein of unknown function (DUF3106) RbsD_FucU PF05025.13 OWF35359.1 - 0.013 15.9 4.9 45 4.5 0.1 5.6 2 2 4 7 7 7 0 RbsD / FucU transport protein family YorP PF09629.10 OWF35359.1 - 0.038 14.2 30.2 50 4.2 0.1 10.3 1 1 9 13 13 13 0 YorP protein OB_NTP_bind PF07717.16 OWF35359.1 - 8.9 6.7 20.1 1.4e+02 2.9 0.0 7.4 1 1 0 3 3 3 0 Oligonucleotide/oligosaccharide-binding (OB)-fold zf-CCCH PF00642.24 OWF35361.1 - 1.4e-06 28.0 24.7 0.00044 20.1 2.2 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OWF35361.1 - 8e-06 25.5 23.3 0.0035 17.1 4.2 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OWF35361.1 - 1.1e-05 25.3 25.9 0.00053 19.9 5.9 3.8 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_3 PF15663.5 OWF35361.1 - 0.00016 21.8 11.3 0.011 16.0 6.8 2.5 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 OWF35361.1 - 0.00042 20.7 27.8 0.0023 18.3 1.7 3.5 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger TSC22 PF01166.18 OWF35361.1 - 0.0056 17.0 0.8 0.021 15.1 0.5 2.1 1 1 1 2 2 2 1 TSC-22/dip/bun family Torus PF16131.5 OWF35361.1 - 0.042 14.5 16.8 0.14 12.8 1.6 3.3 1 1 2 3 3 3 0 Torus domain ZapB PF06005.12 OWF35361.1 - 0.14 12.6 3.4 0.41 11.1 3.4 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 OWF35361.1 - 0.84 9.4 6.6 0.42 10.4 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator TGT_C1 PF14809.6 OWF35362.1 - 8.7e-14 51.6 72.6 50 4.3 0.0 29.3 4 4 39 46 46 46 11 C1 domain of tRNA-guanine transglycosylase dimerisation Tyosinase_C PF18132.1 OWF35363.1 - 0.00019 22.1 0.3 26 5.5 0.0 5.0 1 1 3 6 6 6 1 Tyosinase C-terminal domain TIG PF01833.24 OWF35363.1 - 0.00033 20.7 4.1 1.8 8.7 0.2 4.1 1 1 4 5 5 5 4 IPT/TIG domain DUF1663 PF07909.11 OWF35363.1 - 0.00049 19.0 7.7 6.1 5.5 0.0 5.7 2 2 6 8 8 8 3 Protein of unknown function (DUF1663) RBD PF02196.15 OWF35363.1 - 0.0024 17.9 0.1 80 3.4 0.0 5.1 2 2 3 6 6 6 0 Raf-like Ras-binding domain YniB PF14002.6 OWF35363.1 - 0.33 10.7 2.8 64 3.3 0.1 3.9 2 2 4 6 6 6 0 YniB-like protein Corona_NS4 PF03905.13 OWF35363.1 - 0.45 10.6 24.4 20 5.3 0.1 7.6 8 0 0 8 8 8 0 Coronavirus non-structural protein NS4 CoaE PF01121.20 OWF35365.1 - 1.7e-61 207.0 0.0 2.1e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 OWF35365.1 - 3.5e-06 27.6 0.2 1.2e-05 25.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 OWF35365.1 - 0.0042 17.2 0.2 0.095 12.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Cytidylate_kin PF02224.18 OWF35365.1 - 0.0066 16.2 1.0 0.08 12.7 1.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 OWF35365.1 - 0.0077 16.4 0.7 0.18 12.0 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OWF35365.1 - 0.035 14.5 0.6 1 9.7 0.4 2.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OWF35365.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 OWF35365.1 - 0.085 13.0 0.1 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family Fringe PF02434.16 OWF35366.1 - 1.1e-07 31.6 0.5 1.1e-07 31.6 0.5 2.4 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OWF35366.1 - 1.2e-06 28.5 0.4 0.00049 20.0 0.4 2.8 1 1 0 1 1 1 1 Galactosyltransferase Hid1 PF12722.7 OWF35366.1 - 2.2 6.3 20.2 3.1 5.8 20.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 OWF35366.1 - 4.6 5.9 22.0 7.2 5.3 22.0 1.3 1 0 0 1 1 1 0 Presenilin 7tm_2 PF00002.24 OWF35367.1 - 2.6e-51 174.3 12.6 2.6e-51 174.3 12.6 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF35367.1 - 2.2e-09 37.4 7.8 7.2e-09 35.8 5.5 2.8 3 0 0 3 3 3 1 Hormone receptor domain GAGA_bind PF06217.12 OWF35369.1 - 0.65 10.2 19.8 0.13 12.5 10.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DHHC PF01529.20 OWF35370.1 - 1.1e-25 90.3 14.4 1.1e-25 90.3 14.4 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Innexin PF00876.18 OWF35371.1 - 5.6e-105 351.5 19.1 6.5e-105 351.3 19.1 1.0 1 0 0 1 1 1 1 Innexin Gemini_AC4_5 PF04807.12 OWF35373.1 - 0.55 10.0 9.0 1.4e+02 2.2 0.3 8.5 3 0 0 3 3 3 0 Geminivirus AC4/5 conserved region 7tm_1 PF00001.21 OWF35374.1 - 9e-18 64.5 19.7 9.2e-18 64.5 19.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PDR_CDR PF06422.12 OWF35374.1 - 0.23 11.4 2.4 0.31 10.9 0.5 2.2 2 1 1 3 3 3 0 CDR ABC transporter 7tm_1 PF00001.21 OWF35375.1 - 0.041 13.2 12.7 1.9 7.8 10.4 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DNA_pol_B PF00136.21 OWF35376.1 - 4.5e-149 497.1 0.9 7.1e-149 496.4 0.9 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OWF35376.1 - 2.8e-82 276.6 0.0 5e-82 275.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OWF35376.1 - 1.1e-18 67.5 6.6 2.5e-18 66.3 6.6 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 OWF35376.1 - 0.0098 14.8 3.2 0.033 13.0 0.0 2.7 2 1 0 3 3 3 1 DNA polymerase type B, organellar and viral DZR PF12773.7 OWF35376.1 - 0.94 9.6 5.3 0.47 10.5 0.9 1.9 1 1 1 2 2 2 0 Double zinc ribbon BPL_N PF09825.9 OWF35377.1 - 6.9e-07 28.7 0.1 0.0047 16.1 0.0 2.5 3 0 0 3 3 3 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OWF35377.1 - 0.00025 21.0 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Glyco_hydro_42M PF08532.10 OWF35377.1 - 0.025 14.1 0.5 0.064 12.7 0.1 1.8 2 1 0 2 2 2 0 Beta-galactosidase trimerisation domain Arf PF00025.21 OWF35378.1 - 8.2e-36 123.1 0.0 1e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF35378.1 - 0.00049 19.6 0.0 0.00059 19.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OWF35378.1 - 0.00094 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 OWF35378.1 - 0.037 13.9 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 OWF35378.1 - 0.049 12.8 0.5 0.12 11.6 0.5 1.5 1 1 0 1 1 1 0 G-protein alpha subunit MAR_sialic_bdg PF10564.9 OWF35378.1 - 0.049 13.7 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat GTP_EFTU PF00009.27 OWF35378.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 OWF35379.1 - 3.1e-13 49.3 0.0 4.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 OWF35379.1 - 2.8e-05 24.0 4.1 5.9e-05 23.0 4.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OWF35379.1 - 0.0072 16.1 4.7 0.014 15.2 4.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OWF35379.1 - 0.022 14.5 5.5 0.051 13.3 5.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Aldedh PF00171.22 OWF35380.1 - 3.9e-87 292.7 0.0 4.9e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OWF35380.1 - 0.00011 21.4 0.0 0.00034 19.8 0.0 1.7 1 1 1 2 2 2 1 Acyl-CoA reductase (LuxC) A_deaminase PF00962.22 OWF35381.1 - 1.1e-19 71.0 0.0 1.5e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 OWF35381.1 - 1.8e-19 69.8 0.0 3.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Dimer_Tnp_hAT PF05699.14 OWF35382.1 - 7.2e-21 73.8 4.7 0.69 9.7 3.0 10.6 1 1 1 2 2 2 2 hAT family C-terminal dimerisation region Ribosomal_L32e PF01655.18 OWF35383.1 - 2.4e-53 179.1 5.0 2.8e-53 178.9 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 LRR_8 PF13855.6 OWF35384.1 - 1.3e-50 168.9 100.9 2.2e-09 36.9 7.7 9.4 2 2 8 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 OWF35384.1 - 1.1e-38 130.6 68.6 7.5e-07 29.4 4.1 11.2 4 3 4 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF35384.1 - 2.5e-07 30.3 54.4 7.7 7.5 1.0 16.7 17 3 1 18 18 18 4 Leucine Rich Repeat LRR_9 PF14580.6 OWF35384.1 - 1.4e-06 27.9 27.1 0.0098 15.4 2.9 4.9 2 2 1 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 OWF35384.1 - 0.0015 18.5 5.7 0.035 14.1 1.1 3.7 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 OWF35384.1 - 0.015 15.4 2.3 79 3.4 0.1 5.6 4 2 1 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain FNIP PF05725.12 OWF35384.1 - 2.7 8.2 14.2 14 5.9 0.3 6.2 5 2 0 5 5 5 0 FNIP Repeat Ribosomal_L11_N PF03946.14 OWF35385.1 - 6.8e-19 67.5 0.5 1.1e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OWF35385.1 - 5.2e-18 65.3 0.6 8.6e-18 64.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain CorC_HlyC PF03471.17 OWF35385.1 - 0.027 14.5 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Transporter associated domain Topoisom_bac PF01131.20 OWF35386.1 - 1.7e-118 396.2 0.0 2.1e-118 395.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OWF35386.1 - 3.3e-19 69.0 0.0 6.9e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Fer4_11 PF13247.6 OWF35386.1 - 0.32 11.1 5.3 0.82 9.8 5.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain FoP_duplication PF13865.6 OWF35386.1 - 1.6 9.3 9.8 3.6 8.2 9.8 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ADK_lid PF05191.14 OWF35386.1 - 9.3 6.3 12.1 0.61 10.1 0.8 3.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid MCM PF00493.23 OWF35387.1 - 2e-77 259.3 0.0 4.3e-77 258.2 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OWF35387.1 - 3.2e-21 75.5 1.2 3.2e-21 75.5 1.2 2.6 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 OWF35387.1 - 6.9e-16 58.4 2.0 1.9e-15 57.1 2.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OWF35387.1 - 2.8e-08 33.4 6.8 1.2e-05 24.8 0.0 3.3 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF35387.1 - 3.4e-08 33.6 0.0 7.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OWF35387.1 - 0.00067 19.5 0.0 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OWF35387.1 - 0.011 15.4 0.1 0.23 11.1 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2039 PF10217.9 OWF35387.1 - 0.062 13.6 0.3 0.062 13.6 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) AAA_7 PF12775.7 OWF35387.1 - 0.88 9.1 4.9 0.19 11.2 0.1 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region Laminin_EGF PF00053.24 OWF35390.1 - 8.9e-05 22.6 18.3 8.9e-05 22.6 18.3 4.4 3 1 2 5 5 5 2 Laminin EGF domain TMEM154 PF15102.6 OWF35390.1 - 0.0012 18.8 0.1 0.0038 17.1 0.0 1.8 1 1 0 1 1 1 1 TMEM154 protein family Orthoreo_P10 PF07204.11 OWF35390.1 - 0.022 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MLANA PF14991.6 OWF35390.1 - 0.027 14.7 0.1 0.087 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein melan-A CTV_P6 PF06706.11 OWF35390.1 - 0.051 13.3 0.4 0.099 12.4 0.4 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein SIT PF15330.6 OWF35390.1 - 0.21 12.0 0.7 4.6 7.7 0.0 2.5 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT ABC2_membrane_3 PF12698.7 OWF35390.1 - 1 8.4 2.3 7.7 5.5 0.0 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein Neur_chan_LBD PF02931.23 OWF35391.1 - 1.1e-45 155.8 1.3 1.4e-45 155.4 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF35391.1 - 1.9e-26 93.6 11.8 6.7e-24 85.3 8.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region TPR_2 PF07719.17 OWF35392.1 - 2.6e-15 55.2 0.1 0.023 14.8 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF35392.1 - 7e-14 51.9 3.1 0.031 14.5 0.0 6.8 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF35392.1 - 9e-14 50.6 0.3 0.051 13.4 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF35392.1 - 2.6e-09 36.6 0.0 0.37 11.1 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF35392.1 - 1e-08 35.2 0.0 0.089 13.7 0.0 6.5 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF35392.1 - 5.6e-08 32.3 0.5 6.1 7.1 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF35392.1 - 4.2e-05 24.1 0.0 0.00036 21.1 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF35392.1 - 0.00012 21.7 2.5 0.0054 16.4 0.0 4.0 4 1 1 5 5 5 1 TPR repeat TPR_10 PF13374.6 OWF35392.1 - 0.00013 21.7 4.4 0.048 13.5 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF35392.1 - 0.00072 19.8 3.3 9 6.9 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF35392.1 - 0.0079 16.4 1.8 0.084 13.1 0.0 3.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OWF35392.1 - 0.019 15.0 0.0 25 5.0 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 OWF35392.1 - 0.02 15.4 0.0 8.3 7.0 0.0 3.8 3 1 0 4 4 4 0 Tetratricopeptide repeat Uds1 PF15456.6 OWF35392.1 - 0.69 10.1 4.9 0.83 9.8 3.1 2.0 2 0 0 2 2 2 0 Up-regulated During Septation zf-C4 PF00105.18 OWF35393.1 - 3.1e-32 110.8 14.6 3.1e-32 110.8 14.6 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF35393.1 - 5.1e-23 81.7 1.0 1e-22 80.7 0.1 1.9 1 1 1 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-PARP PF00645.18 OWF35393.1 - 0.065 14.1 5.0 0.43 11.5 0.0 3.1 1 1 2 3 3 3 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RFX_DNA_binding PF02257.15 OWF35394.1 - 1.1e-30 106.0 0.1 2.4e-30 105.0 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 OWF35394.1 - 0.13 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like Inhibitor_I42 PF09394.10 OWF35395.1 - 8.7e-06 26.1 0.0 34 4.9 0.0 8.0 3 3 5 8 8 8 1 Chagasin family peptidase inhibitor I42 Haemocyan_bet_s PF14830.6 OWF35395.1 - 0.0047 16.9 0.0 54 3.8 0.0 5.2 2 2 2 5 5 5 1 Haemocyanin beta-sandwich Ras PF00071.22 OWF35396.1 - 6.7e-49 165.6 1.7 7.3e-49 165.5 0.0 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OWF35396.1 - 1.7e-28 99.3 0.0 3.8e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF35396.1 - 6.4e-15 55.0 0.0 6.4e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_1 PF00036.32 OWF35396.1 - 5.9e-11 41.1 0.5 2.6e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OWF35396.1 - 1.9e-10 39.7 0.8 1e-05 24.8 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF35396.1 - 7e-10 38.0 0.7 0.00027 20.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF35396.1 - 3.7e-08 33.7 0.2 3.7e-08 33.7 0.2 3.0 3 0 0 3 3 3 1 EF-hand domain pair MMR_HSR1 PF01926.23 OWF35396.1 - 4.5e-08 33.2 1.1 2.5e-07 30.8 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 OWF35396.1 - 5.1e-06 26.2 0.9 0.0032 17.3 0.0 2.7 1 1 1 2 2 2 2 EF-hand domain pair GTP_EFTU PF00009.27 OWF35396.1 - 0.00048 19.7 0.0 0.00048 19.7 0.0 2.7 2 2 0 2 2 1 1 Elongation factor Tu GTP binding domain DUF4407 PF14362.6 OWF35396.1 - 1.7 7.9 13.1 3.8 6.8 13.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 OWF35396.1 - 4.7 6.4 15.1 5.4 6.2 9.7 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Trypsin PF00089.26 OWF35397.1 - 4e-49 167.4 2.6 4.6e-49 167.2 2.6 1.0 1 0 0 1 1 1 1 Trypsin SpoIIID PF12116.8 OWF35397.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D PP2C PF00481.21 OWF35398.1 - 1.8e-45 155.6 0.0 2.6e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OWF35398.1 - 0.0016 18.1 0.0 0.0061 16.2 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Transposase_21 PF02992.14 OWF35398.1 - 0.27 10.4 1.3 0.46 9.7 1.3 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Toxin_ToxA PF11584.8 OWF35399.1 - 0.0015 18.5 6.2 3.6 7.6 0.1 5.5 1 1 3 5 5 5 1 Proteinaceous host-selective toxin ToxA PPARgamma_N PF12577.8 OWF35399.1 - 0.043 14.5 5.8 6.3 7.5 0.7 3.8 1 1 1 2 2 2 0 PPAR gamma N-terminal region E7R PF17467.2 OWF35399.1 - 0.051 13.7 14.8 3.5 7.8 0.1 5.1 1 1 4 5 5 5 0 Viral Protein E7 Pkinase_Tyr PF07714.17 OWF35400.1 - 1.2e-88 296.8 0.0 1.7e-88 296.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 OWF35400.1 - 7e-51 171.1 5.3 1e-24 86.8 0.8 2.4 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 OWF35400.1 - 1.2e-39 136.3 0.0 1.8e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GF_recep_IV PF14843.6 OWF35400.1 - 4.1e-35 120.5 122.1 8.7e-19 67.6 33.4 5.9 3 1 2 5 5 5 5 Growth factor receptor domain IV Furin-like PF00757.20 OWF35400.1 - 1.7e-27 96.1 132.0 8.4e-22 77.7 40.2 6.1 2 1 3 6 6 6 4 Furin-like cysteine rich region Kinase-like PF14531.6 OWF35400.1 - 0.007 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF35400.1 - 0.0085 15.5 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF35400.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ETRAMP PF09716.10 OWF35400.1 - 0.081 13.0 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) APH PF01636.23 OWF35400.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DPPIV_N PF00930.21 OWF35401.1 - 1.5e-95 319.9 0.7 2.1e-95 319.5 0.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OWF35401.1 - 1.5e-54 184.7 1.5 2.7e-54 183.9 1.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OWF35401.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF872 PF05915.12 OWF35401.1 - 0.0097 16.1 0.0 0.047 13.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) Peptidase_S15 PF02129.18 OWF35401.1 - 0.017 14.8 2.4 0.22 11.1 0.6 2.3 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 OWF35401.1 - 0.023 14.0 0.0 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIP PF03583.14 OWF35401.1 - 0.042 13.2 1.3 0.53 9.6 0.2 2.2 2 0 0 2 2 2 0 Secretory lipase Glycoprotein_G PF00802.19 OWF35401.1 - 0.048 13.0 0.1 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G Malt_amylase_C PF16657.5 OWF35401.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Str_synth PF03088.16 OWF35401.1 - 0.08 13.1 0.1 6.5 6.9 0.0 3.3 3 0 0 3 3 3 0 Strictosidine synthase Pentapeptide_3 PF13576.6 OWF35402.1 - 9.6e-08 32.1 2.7 1.3 9.3 0.0 5.3 3 3 0 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 OWF35402.1 - 0.018 15.2 9.5 8.1 6.7 1.3 4.1 2 1 2 4 4 4 0 Pentapeptide repeats (9 copies) GLTT PF01744.20 OWF35402.1 - 0.15 11.9 9.4 0.8 9.5 0.2 4.5 5 0 0 5 5 5 0 GLTT repeat (6 copies) SurA_N PF09312.11 OWF35402.1 - 1.3 9.2 7.8 4.7 7.3 0.8 2.4 1 1 2 3 3 3 0 SurA N-terminal domain Pentapeptide PF00805.22 OWF35402.1 - 6.3 6.5 8.7 23 4.8 0.4 4.1 3 2 1 4 4 4 0 Pentapeptide repeats (8 copies) Pyrid_ox_like PF16242.5 OWF35404.1 - 3.5e-08 33.2 0.0 3 7.4 0.0 5.6 1 1 6 7 7 7 3 Pyridoxamine 5'-phosphate oxidase like FtsK_SpoIIIE_N PF12538.8 OWF35404.1 - 4.5e-06 26.9 9.6 28 5.0 0.1 8.6 3 3 6 9 9 9 0 DNA transporter DUF4176 PF13780.6 OWF35404.1 - 0.0019 18.2 7.8 32 4.7 0.1 6.0 1 1 4 7 7 7 0 Domain of unknown function (DUF4176) DUF5070 PF16802.5 OWF35404.1 - 0.0035 17.3 0.4 62 3.6 0.0 4.0 1 1 4 5 5 5 0 Domain of unknown function (DUF5070) SUKH_6 PF14568.6 OWF35404.1 - 0.016 15.6 19.8 2.3 8.6 1.0 5.6 1 1 2 3 3 3 0 SMI1-KNR4 cell-wall DUF4994 PF16385.5 OWF35404.1 - 0.048 13.6 2.8 77 3.3 0.0 6.0 1 1 4 7 7 7 0 Domain of unknown function Arm-DNA-bind_1 PF09003.10 OWF35404.1 - 0.24 11.6 18.8 33 4.7 0.3 6.9 1 1 7 8 8 8 0 Bacteriophage lambda integrase, Arm DNA-binding domain YL1_C PF08265.11 OWF35404.1 - 0.56 10.0 6.4 96 2.9 0.2 5.7 6 0 0 6 6 6 0 YL1 nuclear protein C-terminal domain Mucin-like PF16058.5 OWF35404.1 - 1.3 9.2 4.3 7.8 6.7 0.1 3.3 3 1 0 3 3 3 0 Mucin-like DUF5077 PF16871.5 OWF35404.1 - 2.8 7.8 7.7 50 3.7 0.0 4.2 1 1 4 6 6 6 0 Domain of unknown function (DUF5077) DUF4348 PF14254.6 OWF35404.1 - 5.1 6.4 9.8 15 4.9 0.1 4.6 1 1 3 5 5 5 0 Domain of unknown function (DUF4348) DUF5118 PF17162.4 OWF35404.1 - 6.9 6.6 6.3 80 3.2 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5118) GcrA PF07750.11 OWF35404.1 - 8 6.9 5.1 25 5.2 0.3 3.6 3 2 2 5 5 5 0 GcrA cell cycle regulator Pyrid_ox_like PF16242.5 OWF35405.1 - 5.7e-05 22.7 0.0 1.5 8.4 0.0 2.9 1 1 2 3 3 3 2 Pyridoxamine 5'-phosphate oxidase like DUF5050 PF16472.5 OWF35405.1 - 0.007 15.6 4.6 0.078 12.2 4.6 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) Mucin-like PF16058.5 OWF35405.1 - 0.008 16.2 1.0 0.044 13.9 0.9 2.0 1 1 0 1 1 1 1 Mucin-like B2-adapt-app_C PF09066.10 OWF35405.1 - 0.014 15.5 0.0 4.7 7.4 0.0 3.3 1 1 4 5 5 5 0 Beta2-adaptin appendage, C-terminal sub-domain DUF4994 PF16385.5 OWF35405.1 - 0.017 15.0 0.7 21 5.1 0.0 4.0 1 1 3 4 4 4 0 Domain of unknown function Reg_prop PF07494.11 OWF35405.1 - 0.04 14.1 0.2 1.7e+02 3.0 0.0 4.8 2 2 4 6 6 6 0 Two component regulator propeller DUF4176 PF13780.6 OWF35405.1 - 0.1 12.6 0.4 47 4.1 0.0 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4176) SUKH_6 PF14568.6 OWF35405.1 - 0.16 12.4 5.2 3.4 8.1 0.3 3.1 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall Arm-DNA-bind_1 PF09003.10 OWF35405.1 - 0.18 12.0 5.6 8.6 6.6 0.2 3.3 1 1 2 3 3 3 0 Bacteriophage lambda integrase, Arm DNA-binding domain GST_C_6 PF17171.4 OWF35405.1 - 2.9 7.7 10.2 1.1e+02 2.7 0.1 6.0 3 1 3 6 6 6 0 Glutathione S-transferase, C-terminal domain DUF4950 PF16308.5 OWF35405.1 - 8 6.4 5.8 50 3.8 0.1 3.3 1 1 4 5 5 5 0 Domain of unknown function (DUF4950) YL1_C PF08265.11 OWF35405.1 - 8.2 6.3 11.2 1e+02 2.8 0.1 5.2 7 0 0 7 7 7 0 YL1 nuclear protein C-terminal domain Branch PF02485.21 OWF35406.1 - 1.3e-41 142.7 0.0 1.7e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme TPR_2 PF07719.17 OWF35408.1 - 1.8e-38 127.5 30.7 3.3e-06 26.8 0.0 10.1 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 OWF35408.1 - 3.5e-37 124.7 31.8 6e-07 29.0 0.6 9.8 8 1 2 10 10 10 7 Tetratricopeptide repeat DnaJ PF00226.31 OWF35408.1 - 1.8e-23 82.4 3.5 1.8e-23 82.4 3.5 2.8 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 OWF35408.1 - 1.2e-21 76.0 17.9 1.2e-09 37.7 1.0 7.1 5 2 2 7 7 7 4 TPR repeat TPR_8 PF13181.6 OWF35408.1 - 1.4e-21 74.8 25.6 0.00019 21.4 1.0 9.9 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 OWF35408.1 - 2.8e-15 56.4 26.0 0.00096 19.4 0.4 8.3 3 1 6 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 OWF35408.1 - 4.5e-15 55.1 10.7 0.31 12.0 0.1 8.3 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 OWF35408.1 - 8.4e-15 54.0 10.9 0.00014 22.0 0.9 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF35408.1 - 5.7e-11 42.8 24.1 0.0015 19.0 0.5 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF35408.1 - 4.7e-10 40.0 12.0 0.0058 17.3 0.0 6.4 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF35408.1 - 1.2e-08 34.9 10.1 0.031 14.4 0.2 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 OWF35408.1 - 3.6e-08 33.5 15.5 0.023 15.3 0.6 7.0 6 1 2 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF35408.1 - 5e-07 29.3 12.7 0.0071 16.3 0.4 7.2 7 1 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF35408.1 - 0.0005 20.3 26.4 0.16 12.2 0.2 5.3 2 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 OWF35408.1 - 0.0014 18.1 4.3 0.048 13.0 0.6 3.2 1 1 2 3 3 3 1 MalT-like TPR region SHNi-TPR PF10516.9 OWF35408.1 - 0.0018 17.7 1.7 0.2 11.1 0.0 4.1 4 0 0 4 4 4 1 SHNi-TPR DUF627 PF04781.12 OWF35408.1 - 0.0034 17.4 2.1 0.014 15.4 0.1 3.0 3 1 0 3 3 2 1 Protein of unknown function (DUF627) BTAD PF03704.17 OWF35408.1 - 0.0049 17.3 10.5 0.96 9.9 0.3 4.5 2 2 2 5 5 5 2 Bacterial transcriptional activator domain Rapsyn_N PF10579.9 OWF35408.1 - 0.05 13.7 5.6 15 5.7 0.4 4.3 4 2 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TAF8_C PF10406.9 OWF35408.1 - 0.092 13.3 0.2 0.4 11.3 0.2 2.0 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Alkyl_sulf_dimr PF14863.6 OWF35408.1 - 0.29 11.6 0.1 0.29 11.6 0.1 4.0 4 1 1 5 5 4 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 OWF35408.1 - 0.3 11.5 9.8 3.3 8.1 0.6 4.7 3 1 0 4 4 4 0 Tetratricopeptide repeat Fer4_13 PF13370.6 OWF35408.1 - 0.52 10.9 3.8 1 10.0 0.1 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I TPR_10 PF13374.6 OWF35408.1 - 0.65 9.9 23.2 2.4 8.2 1.3 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF357 PF04010.13 OWF35408.1 - 0.74 9.9 5.7 6.9 6.8 0.2 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.6 OWF35408.1 - 8.4 6.5 18.9 15 5.7 0.0 6.1 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Vps51 PF08700.11 OWF35409.1 - 0.0035 17.4 0.1 0.011 15.8 0.1 1.8 1 0 0 1 1 1 1 Vps51/Vps67 DUF759 PF05537.11 OWF35409.1 - 0.014 14.3 1.2 0.022 13.7 1.2 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) p450 PF00067.22 OWF35410.1 - 1.2e-95 320.9 0.0 1.4e-95 320.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Filo_VP35 PF02097.15 OWF35410.1 - 0.0092 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Filoviridae VP35 Exo_endo_phos PF03372.23 OWF35411.1 - 8.1e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5496 PF17600.2 OWF35411.1 - 0.25 11.4 1.2 0.86 9.7 0.0 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5496) AAA_33 PF13671.6 OWF35412.1 - 3.4e-12 46.7 0.0 8.7e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF35412.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OWF35412.1 - 0.0018 18.8 0.1 0.0052 17.3 0.0 1.9 2 1 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 OWF35412.1 - 0.0021 17.4 0.1 0.011 15.0 0.0 2.2 2 1 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 OWF35412.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase PRK PF00485.18 OWF35412.1 - 0.0054 16.5 0.2 0.015 15.0 0.0 1.7 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 OWF35412.1 - 0.0089 16.4 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 OWF35412.1 - 0.012 15.3 0.0 0.038 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 OWF35412.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NACHT PF05729.12 OWF35412.1 - 0.023 14.6 0.0 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_5 PF07728.14 OWF35412.1 - 0.048 13.7 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OWF35412.1 - 0.053 13.4 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Peptidase_C97 PF05903.14 OWF35412.1 - 0.055 13.3 0.1 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain AAA_22 PF13401.6 OWF35412.1 - 0.087 13.1 0.1 0.26 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OWF35412.1 - 0.1 11.9 0.3 0.88 8.8 0.1 2.1 1 1 1 2 2 2 0 6-phosphofructo-2-kinase AAA_23 PF13476.6 OWF35412.1 - 0.11 12.9 0.1 0.55 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OWF35412.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PB1 PF00564.24 OWF35413.1 - 5.4e-08 32.7 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain tRNA_U5-meth_tr PF05958.11 OWF35413.1 - 0.047 12.7 0.4 0.062 12.3 0.4 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase KinB_sensor PF16767.5 OWF35413.1 - 0.057 13.9 0.1 0.083 13.4 0.1 1.3 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB RXT2_N PF08595.11 OWF35413.1 - 0.085 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pkinase PF00069.25 OWF35414.1 - 1.6e-69 234.2 0.0 1.8e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35414.1 - 1.3e-43 149.2 0.0 1.6e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF35414.1 - 6.3e-06 25.7 0.0 0.00087 18.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OWF35414.1 - 0.0024 17.8 0.1 1.4 8.8 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF35414.1 - 0.0045 15.8 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OWF35414.1 - 0.0081 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF4573 PF15140.6 OWF35416.1 - 8.3e-50 169.0 40.3 2.4e-06 27.4 1.0 8.4 1 1 1 4 4 4 4 Domain of unknown function (DUF4573) DUF3106 PF11304.8 OWF35416.1 - 8.6e-11 42.2 40.8 30 5.2 0.2 12.0 1 1 2 6 6 6 6 Protein of unknown function (DUF3106) Arm PF00514.23 OWF35417.1 - 5.1e-64 210.5 20.0 4.4e-07 29.7 0.0 13.3 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF35417.1 - 4.4e-20 71.9 8.0 5.9e-05 23.4 0.0 6.8 3 2 4 7 7 7 5 HEAT repeats Adaptin_N PF01602.20 OWF35417.1 - 1e-09 37.5 2.8 3.9e-05 22.4 0.0 4.1 1 1 2 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 OWF35417.1 - 3.4e-09 37.0 8.2 0.043 14.3 0.1 7.0 8 0 0 8 8 6 3 HEAT-like repeat Arm_2 PF04826.13 OWF35417.1 - 1.7e-08 34.3 3.3 0.08 12.4 0.1 6.2 4 2 3 7 7 7 2 Armadillo-like V-ATPase_H_C PF11698.8 OWF35417.1 - 1.8e-08 34.5 8.7 3.7 7.7 0.0 7.0 3 3 3 7 7 7 4 V-ATPase subunit H HEAT PF02985.22 OWF35417.1 - 5.3e-07 29.4 14.2 12 6.5 0.1 8.3 9 0 0 9 9 8 2 HEAT repeat KAP PF05804.12 OWF35417.1 - 8.8e-07 27.5 1.3 0.68 8.0 0.0 4.1 2 1 2 4 4 4 4 Kinesin-associated protein (KAP) Cnd1 PF12717.7 OWF35417.1 - 1.5e-06 28.4 2.3 2.1 8.4 0.0 5.0 2 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OWF35417.1 - 4.5e-05 24.0 0.0 12 6.6 0.0 4.0 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 OWF35417.1 - 0.00023 21.2 7.6 0.75 9.7 0.1 4.4 3 1 1 4 4 4 2 Myosin-binding striated muscle assembly central Spo0A_C PF08769.11 OWF35417.1 - 0.064 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal RasGEF_N_2 PF14663.6 OWF35417.1 - 3.5 8.1 8.2 31 5.0 0.0 5.6 7 0 0 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Tetraspanin PF00335.20 OWF35418.1 - 1.4e-55 188.5 13.6 1.6e-55 188.4 13.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF1218 PF06749.12 OWF35418.1 - 0.024 15.2 6.8 0.55 10.8 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) YfhO PF09586.10 OWF35418.1 - 0.41 8.8 2.4 0.49 8.6 2.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Frizzled PF01534.17 OWF35419.1 - 1.6e-137 457.9 23.5 2.7e-137 457.2 23.5 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 OWF35419.1 - 2.2e-34 118.4 3.3 5.1e-34 117.2 3.3 1.6 1 0 0 1 1 1 1 Fz domain MBT PF02820.18 OWF35421.1 - 0.43 11.0 15.6 1.2e+02 3.2 0.0 8.7 11 1 1 12 12 12 0 mbt repeat NCOA_u2 PF16665.5 OWF35421.1 - 1.3 9.3 31.0 25 5.2 0.2 6.1 1 1 6 7 7 7 0 Unstructured region on nuclear receptor coactivator protein Nop PF01798.18 OWF35422.1 - 9.8e-85 283.7 0.1 9.8e-85 283.7 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OWF35422.1 - 1.9e-20 73.0 5.7 1.9e-20 73.0 5.7 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain C9orf72-like PF15019.6 OWF35422.1 - 0.02 14.5 0.4 0.036 13.6 0.4 1.4 1 0 0 1 1 1 0 C9orf72-like protein family tRNA-synt_His PF13393.6 OWF35422.1 - 0.28 10.4 2.0 3.2 6.9 1.7 2.3 2 0 0 2 2 2 0 Histidyl-tRNA synthetase p450 PF00067.22 OWF35423.1 - 3.4e-100 336.0 0.1 4.1e-100 335.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Syndecan PF01034.20 OWF35424.1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain LDB19 PF13002.7 OWF35424.1 - 0.0078 15.9 2.5 0.0078 15.9 2.5 2.2 2 1 0 2 2 2 1 Arrestin_N terminal like EphA2_TM PF14575.6 OWF35424.1 - 0.015 16.1 0.0 0.05 14.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 OWF35424.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Toxin_7 PF05980.12 OWF35424.1 - 2.4 8.5 6.7 5.8 7.3 6.7 1.7 1 0 0 1 1 1 0 Toxin 7 Guanylate_cyc PF00211.20 OWF35426.1 - 1.1e-52 178.3 0.0 1.9e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 OWF35426.1 - 1.6e-27 97.5 0.7 3e-27 96.6 0.2 1.6 2 0 0 2 2 2 1 Nitrate and nitrite sensing HNOBA PF07701.14 OWF35426.1 - 5.5e-08 32.5 0.2 1.1e-07 31.6 0.2 1.4 1 0 0 1 1 1 1 Heme NO binding associated Siva PF05458.12 OWF35428.1 - 0.021 14.5 13.4 16 5.1 0.0 8.4 1 1 9 12 12 12 0 Cd27 binding protein (Siva) Hairy_orange PF07527.13 OWF35429.1 - 5.7e-16 58.4 0.0 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 OWF35429.1 - 1.7e-14 53.5 5.8 3.3e-14 52.6 5.6 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4505 PF14956.6 OWF35431.1 - 0.0016 18.2 18.6 3.5 7.3 4.4 5.7 1 1 3 4 4 4 2 Domain of unknown function (DUF4505) Frag1 PF10277.9 OWF35431.1 - 0.0097 15.5 5.4 0.83 9.1 3.8 3.4 1 1 1 2 2 2 1 Frag1/DRAM/Sfk1 family PEPCK_ATP PF01293.20 OWF35431.1 - 0.059 12.0 0.0 20 3.7 0.0 3.3 2 1 2 4 4 4 0 Phosphoenolpyruvate carboxykinase DUF4999 PF16390.5 OWF35431.1 - 0.19 12.0 1.2 86 3.5 0.0 4.1 1 1 3 5 5 5 0 Domain of unknown function LRR_1 PF00560.33 OWF35431.1 - 0.45 11.2 6.3 1.4e+02 3.7 0.6 5.4 1 1 1 2 2 2 0 Leucine Rich Repeat ACI44 PF15270.6 OWF35431.1 - 2.5 8.4 10.6 40 4.5 0.6 4.9 1 1 5 6 6 6 0 Metallo-carboxypeptidase inhibitor Cornifin PF02389.15 OWF35433.1 - 0.0031 17.7 0.4 0.0042 17.3 0.4 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family ECR1_N PF14382.6 OWF35434.1 - 0.064 13.1 5.2 1.6e+02 2.2 0.0 5.4 7 0 0 7 7 7 0 Exosome complex exonuclease RRP4 N-terminal region MAPEG PF01124.18 OWF35434.1 - 5.2 7.0 10.6 7.5 6.5 2.1 3.0 1 1 1 2 2 2 0 MAPEG family XRN_N PF03159.18 OWF35435.1 - 4.9e-93 311.0 0.0 4.9e-93 311.0 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OWF35435.1 - 1.4e-90 304.4 1.7 1.4e-90 304.4 1.7 2.6 3 0 0 3 3 3 1 Xrn1 helical domain XRN1_D1 PF18332.1 OWF35435.1 - 9.7e-30 103.8 0.1 2.5e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 OWF35435.1 - 2.6e-18 65.9 0.0 4.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 OWF35435.1 - 1.1e-06 28.7 0.0 5.1e-06 26.6 0.0 2.2 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain dsrm PF00035.26 OWF35435.1 - 0.053 14.2 0.2 0.37 11.5 0.0 2.6 3 0 0 3 3 3 0 Double-stranded RNA binding motif SPC12 PF06645.13 OWF35436.1 - 9.4e-31 105.7 2.8 1.3e-30 105.3 2.8 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) CrgA PF06781.12 OWF35436.1 - 0.012 15.6 0.3 0.023 14.7 0.0 1.7 2 1 0 2 2 2 0 Cell division protein CrgA DUF3040 PF11239.8 OWF35436.1 - 0.03 14.6 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1449 PF07290.11 OWF35436.1 - 0.072 12.7 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF3341 PF11821.8 OWF35436.1 - 0.11 12.1 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) TPR_1 PF00515.28 OWF35438.1 - 2.5e-11 42.9 0.7 0.00064 19.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF35438.1 - 5e-10 38.7 0.3 0.0027 17.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF35438.1 - 4.8e-05 23.6 2.8 0.00012 22.3 1.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF35438.1 - 4.9e-05 22.9 0.1 0.94 9.2 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 OWF35438.1 - 0.00065 19.8 1.3 0.019 15.1 0.6 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF35438.1 - 0.0016 18.5 0.1 3.2 8.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF357 PF04010.13 OWF35438.1 - 0.0057 16.7 0.1 0.046 13.8 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF357) TPR_17 PF13431.6 OWF35438.1 - 0.0063 16.8 0.1 0.052 13.9 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF35438.1 - 0.031 14.1 0.2 0.031 14.1 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF29 PF01724.16 OWF35439.1 - 0.032 14.5 0.1 0.068 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF674 PF05056.12 OWF35439.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF674) DUF29 PF01724.16 OWF35440.1 - 0.0046 17.2 0.1 0.013 15.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF29 DUF674 PF05056.12 OWF35440.1 - 0.055 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Ank_4 PF13637.6 OWF35441.1 - 1.3e-11 44.8 0.0 0.00073 20.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF35441.1 - 1.7e-09 37.6 0.0 0.019 15.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OWF35441.1 - 4.9e-09 36.7 0.0 7.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF35441.1 - 1.4e-08 34.8 0.4 1.7e-06 28.2 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF35441.1 - 0.00033 20.9 0.1 9.9 7.1 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat HAP1_N PF04849.13 OWF35442.1 - 0.0039 16.4 2.4 0.0039 16.4 2.4 4.7 1 1 3 4 4 4 1 HAP1 N-terminal conserved region DUF3698 PF12479.8 OWF35442.1 - 0.0073 16.8 0.1 0.0073 16.8 0.1 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3698) Leu_zip PF15294.6 OWF35442.1 - 0.043 13.3 66.4 0.25 10.8 16.7 4.0 2 1 2 4 4 4 0 Leucine zipper SlyX PF04102.12 OWF35442.1 - 0.09 13.4 0.5 0.09 13.4 0.5 6.4 6 3 3 9 9 9 0 SlyX MscS_porin PF12795.7 OWF35442.1 - 1.6 8.3 45.5 0.8 9.2 2.3 4.3 2 1 1 4 4 4 0 Mechanosensitive ion channel porin domain FUSC PF04632.12 OWF35442.1 - 5.4 5.4 9.9 0.2 10.2 1.9 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Cnd1 PF12717.7 OWF35443.1 - 1.1e-58 197.8 5.3 2.6e-52 177.1 0.1 4.5 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 OWF35443.1 - 2.3e-34 118.7 1.0 5.6e-34 117.4 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 OWF35443.1 - 1.1e-08 34.1 4.8 0.00011 20.9 0.2 4.0 3 2 1 4 4 4 3 Adaptin N terminal region HEAT PF02985.22 OWF35443.1 - 6.3e-07 29.1 3.1 1.1 9.7 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 OWF35443.1 - 3.5e-05 24.1 0.9 0.01 16.2 0.0 4.9 6 1 1 7 7 7 1 HEAT repeats Cnd3 PF12719.7 OWF35443.1 - 0.009 15.2 0.6 0.009 15.2 0.6 2.8 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 OWF35443.1 - 0.064 12.8 4.4 1.3 8.5 0.1 3.0 3 0 0 3 3 3 0 CLASP N terminal Reticulon PF02453.17 OWF35444.1 - 0.043 13.8 0.3 0.12 12.4 0.3 1.7 1 0 0 1 1 1 0 Reticulon DUF4834 PF16118.5 OWF35444.1 - 0.28 12.2 0.1 0.28 12.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Proteasome PF00227.26 OWF35445.1 - 1.9e-35 122.1 0.0 2.2e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Man-6-P_recep PF02157.15 OWF35446.1 - 1.1e-78 263.8 0.1 1.3e-78 263.6 0.1 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OWF35446.1 - 9.5e-14 51.9 0.0 1.3e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OWF35446.1 - 0.011 15.8 0.3 1.2 9.2 0.1 2.4 2 1 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat DUF3149 PF11346.8 OWF35446.1 - 3.4 7.4 5.9 7.2 6.3 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) LRR_8 PF13855.6 OWF35447.1 - 6.5e-09 35.4 1.8 1.4e-06 27.9 0.0 3.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 OWF35447.1 - 4e-08 33.3 0.5 0.00033 20.6 0.3 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF35447.1 - 4.2 7.9 8.2 4.1 8.0 0.1 3.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF35448.1 - 3.4e-08 33.5 1.5 0.0012 18.8 0.1 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OWF35448.1 - 9.4e-08 31.7 2.6 7.5e-05 22.4 0.9 2.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF35448.1 - 0.0018 18.6 6.1 0.18 12.3 2.4 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Folate_carrier PF01770.18 OWF35448.1 - 0.0058 15.4 0.0 0.0091 14.8 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier DUF4957 PF16318.5 OWF35448.1 - 0.071 13.0 8.6 0.07 13.1 1.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4957) LRR_9 PF14580.6 OWF35448.1 - 0.098 12.2 0.2 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Beta_helix PF13229.6 OWF35448.1 - 0.16 11.8 4.4 0.51 10.2 4.6 1.6 1 1 0 1 1 1 0 Right handed beta helix region HRG PF16954.5 OWF35448.1 - 2.1 8.8 5.6 4.5 7.8 0.6 2.8 1 1 1 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene LRR_8 PF13855.6 OWF35449.1 - 8.5e-07 28.6 0.4 0.00073 19.2 0.0 2.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_5 PF13306.6 OWF35449.1 - 9.5e-07 28.8 0.0 0.05 13.6 0.0 3.3 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF4576 PF15144.6 OWF35449.1 - 0.16 11.9 0.0 1 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) LRR_8 PF13855.6 OWF35450.1 - 4.8e-10 39.1 0.0 2.7e-05 23.9 0.1 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_8 PF13855.6 OWF35451.1 - 3.1e-09 36.5 14.0 5.3e-07 29.3 4.7 3.7 2 2 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 OWF35451.1 - 0.3 11.8 5.7 25 5.9 0.8 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 OWF35451.1 - 8.6 6.9 8.6 0.43 11.1 1.6 2.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Troponin PF00992.20 OWF35453.1 - 2.9e-34 118.3 16.2 2.9e-34 118.3 16.2 4.7 3 1 0 3 3 3 1 Troponin Fez1 PF06818.15 OWF35453.1 - 0.022 15.2 3.4 0.022 15.2 3.4 4.3 1 1 1 3 3 3 0 Fez1 Syja_N PF02383.18 OWF35454.1 - 6.4e-68 229.4 0.1 9.7e-68 228.8 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.11 OWF35454.1 - 1.2e-36 125.8 1.3 1.3e-36 125.7 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 OWF35454.1 - 1.4e-11 44.4 0.1 2.4e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family G-patch PF01585.23 OWF35455.1 - 1.3e-12 47.4 0.3 3.6e-12 46.0 0.3 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OWF35455.1 - 0.00075 19.5 0.2 0.00075 19.5 0.2 3.4 4 0 0 4 4 4 1 G-patch domain Pkinase PF00069.25 OWF35456.1 - 5.2e-69 232.5 0.1 7.6e-69 232.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 OWF35456.1 - 2.5e-43 146.1 0.7 2.3e-21 75.7 0.2 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 OWF35456.1 - 4.2e-37 127.9 0.0 6.3e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF35456.1 - 2.4e-10 40.2 0.0 7.6e-08 32.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OWF35456.1 - 2e-07 30.2 0.0 3.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Mannosyl_trans2 PF04188.13 OWF35457.1 - 2.3e-92 310.7 28.1 3e-92 310.3 28.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Ada3 PF10198.9 OWF35458.1 - 2.8e-24 85.8 14.3 2.2e-23 82.8 13.6 2.4 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Microtub_bind PF13931.6 OWF35458.1 - 0.03 14.7 4.7 0.12 12.8 4.7 2.0 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding BTB PF00651.31 OWF35459.1 - 9.7e-30 103.1 0.3 1.1e-13 51.4 0.0 3.7 3 1 1 4 4 4 2 BTB/POZ domain Ank_5 PF13857.6 OWF35459.1 - 1.4e-06 28.5 0.0 4.6e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF35459.1 - 2.1e-06 27.6 0.0 0.00041 20.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OWF35459.1 - 2.6e-05 24.7 0.0 8.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35459.1 - 0.00047 20.7 0.0 0.0015 19.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF35459.1 - 0.012 16.1 0.0 0.044 14.2 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 OWF35460.1 - 6.4e-33 113.2 0.2 2.7e-12 47.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35460.1 - 2.1e-32 111.1 0.2 4.2e-10 40.0 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) DHHC PF01529.20 OWF35460.1 - 5.3e-32 110.7 17.3 5.3e-32 110.7 17.3 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.30 OWF35460.1 - 7.7e-25 86.2 2.2 4.3e-06 26.9 0.3 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OWF35460.1 - 8.9e-25 84.1 0.4 0.0017 18.6 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OWF35460.1 - 2.1e-22 78.9 2.5 3.2e-06 27.3 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (many copies) LRR_9 PF14580.6 OWF35460.1 - 1.8e-15 56.9 7.1 1.6e-13 50.6 3.6 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 OWF35460.1 - 1.3e-05 25.4 9.3 0.00081 19.7 1.8 3.4 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF35460.1 - 0.00024 20.8 9.6 0.006 16.3 3.7 2.5 1 1 2 3 3 3 3 Leucine rich repeat Pkinase PF00069.25 OWF35461.1 - 3.8e-67 226.4 0.1 5.1e-67 226.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35461.1 - 3.1e-44 151.2 0.0 4.8e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF35461.1 - 2.9e-09 36.7 0.0 5.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF35461.1 - 0.02 13.7 0.0 0.044 12.6 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OWF35461.1 - 0.053 13.4 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S13_N PF08069.12 OWF35462.1 - 4.9e-32 109.8 0.1 9.4e-32 108.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OWF35462.1 - 8.2e-15 54.8 2.7 1.3e-14 54.2 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OWF35462.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain KH_8 PF17903.1 OWF35463.1 - 4.4e-29 100.4 0.0 4.4e-29 100.4 0.0 2.1 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 OWF35463.1 - 0.0011 18.8 0.2 0.0072 16.1 0.0 2.3 2 0 0 2 2 2 1 KH domain Pfg27 PF09216.10 OWF35463.1 - 0.005 16.7 1.2 0.0089 15.9 0.0 2.0 2 0 0 2 2 2 1 Pfg27 Afi1 PF07792.12 OWF35463.1 - 0.095 13.2 4.0 0.16 12.5 4.0 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking GREB1 PF15782.5 OWF35463.1 - 0.68 7.0 6.6 0.77 6.8 6.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 OWF35463.1 - 4.3 6.0 4.8 5.2 5.7 4.8 1.1 1 0 0 1 1 1 0 Presenilin Thymidylat_synt PF00303.19 OWF35464.1 - 0.042 13.0 0.1 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 Thymidylate synthase Ig_3 PF13927.6 OWF35465.1 - 3.5e-178 578.7 149.7 1.2e-11 45.1 5.1 18.2 18 0 0 18 18 18 18 Immunoglobulin domain I-set PF07679.16 OWF35465.1 - 2.4e-163 530.7 58.2 1.1e-11 44.6 0.2 18.5 18 0 0 18 18 18 18 Immunoglobulin I-set domain ig PF00047.25 OWF35465.1 - 1.2e-108 355.5 113.8 1e-07 32.0 0.2 18.6 18 1 0 18 18 18 18 Immunoglobulin domain Ig_2 PF13895.6 OWF35465.1 - 1.9e-102 335.7 128.7 3.6e-08 33.6 0.9 18.3 18 0 0 18 18 18 18 Immunoglobulin domain V-set PF07686.17 OWF35465.1 - 2.2e-86 285.3 91.1 1.8e-08 34.5 1.5 25.7 18 11 0 18 18 18 17 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF35465.1 - 1.6e-26 92.2 8.0 0.17 12.0 0.0 15.5 15 1 2 17 17 17 6 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 OWF35465.1 - 9.2e-17 61.2 2.2 2.7 8.4 0.0 14.1 16 0 0 16 16 16 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 OWF35465.1 - 1.4e-16 60.3 41.1 0.42 10.7 0.0 16.7 18 0 0 18 18 18 5 C17orf99 Ig domain Ig_6 PF18452.1 OWF35465.1 - 8.3e-16 57.3 10.1 4.4 6.9 0.0 13.7 16 0 0 16 16 15 3 Immunoglobulin domain Receptor_2B4 PF11465.8 OWF35465.1 - 6.7e-14 52.0 26.6 1.7 8.9 0.0 14.6 15 2 2 17 17 17 3 Natural killer cell receptor 2B4 Ig_4 PF16680.5 OWF35465.1 - 1.2e-11 44.7 9.0 3.6 7.9 0.1 14.0 16 1 0 16 16 16 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 OWF35465.1 - 0.00016 22.0 41.5 0.55 10.6 0.2 12.2 14 0 0 14 14 14 1 Immunoglobulin C1-set domain PRIMA1 PF16101.5 OWF35465.1 - 0.015 15.4 2.5 0.027 14.5 0.8 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF3789 PF12664.7 OWF35465.1 - 0.1 12.3 0.1 0.37 10.6 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) TMIE PF16038.5 OWF35465.1 - 1.5 8.8 4.3 3 7.8 4.3 1.4 1 0 0 1 1 1 0 TMIE protein Pentapeptide_4 PF13599.6 OWF35466.1 - 2.1e-06 27.8 16.4 0.00094 19.3 4.1 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) HC2 PF07382.11 OWF35467.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 ASFV_J13L PF05568.11 OWF35467.1 - 0.17 11.6 2.0 13 5.5 0.2 3.1 1 1 1 2 2 2 0 African swine fever virus J13L protein Luteo_PO PF04662.13 OWF35467.1 - 2.1 8.0 4.9 4.5 6.9 0.2 2.7 1 1 2 3 3 3 0 Luteovirus P0 protein Neur_chan_LBD PF02931.23 OWF35468.1 - 2.1e-18 66.6 1.5 3.8e-18 65.7 1.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF35468.1 - 1.1e-12 48.6 5.0 2.5e-12 47.4 0.7 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4860 PF16152.5 OWF35468.1 - 0.17 11.8 0.3 12 5.9 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4860) TC1 PF15063.6 OWF35469.1 - 0.058 13.3 0.0 28 4.7 0.0 3.4 4 0 0 4 4 4 0 Thyroid cancer protein 1 IQ PF00612.27 OWF35469.1 - 0.1 12.5 0.6 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4031 PF13223.6 OWF35469.1 - 0.26 11.5 2.6 11 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4031) NAD_binding_10 PF13460.6 OWF35470.1 - 1.3e-06 28.4 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OWF35470.1 - 0.02 15.3 0.0 0.034 14.6 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.10 OWF35470.1 - 0.043 13.3 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 HIM1 SOCS_box PF07525.16 OWF35471.1 - 1.4e-05 25.3 2.0 2.9e-05 24.3 0.1 2.5 3 0 0 3 3 3 1 SOCS box Aminotran_1_2 PF00155.21 OWF35472.1 - 2.2e-72 244.3 0.0 2.5e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OWF35472.1 - 7.2e-06 25.2 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OWF35472.1 - 4.3e-05 22.2 0.0 6.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OWF35472.1 - 0.038 13.3 0.0 0.14 11.4 0.0 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cnd1 PF12717.7 OWF35473.1 - 7.3e-28 97.6 17.6 5.4e-22 78.5 0.1 7.7 7 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OWF35473.1 - 1.3e-08 35.1 4.9 0.41 11.1 0.4 5.2 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 OWF35473.1 - 3.1e-07 30.1 12.8 0.16 12.3 0.1 6.7 6 0 0 6 6 6 3 HEAT repeat CLASP_N PF12348.8 OWF35473.1 - 5.6e-05 22.8 4.3 0.12 12.0 0.0 5.1 5 1 0 5 5 5 2 CLASP N terminal Cohesin_HEAT PF12765.7 OWF35473.1 - 9.4e-05 22.6 1.8 0.59 10.5 0.1 3.9 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 OWF35473.1 - 0.00012 20.8 0.9 0.00012 20.8 0.9 4.2 4 2 0 4 4 4 1 Adaptin N terminal region Cnd3 PF12719.7 OWF35473.1 - 0.00091 18.5 0.9 0.005 16.1 0.2 2.6 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 OWF35473.1 - 0.0033 17.9 8.9 11 6.7 0.0 6.1 6 0 0 6 6 6 2 HEAT-like repeat Nipped-B_C PF12830.7 OWF35473.1 - 0.0072 16.3 1.3 0.033 14.1 0.4 2.8 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus DUF4744 PF15918.5 OWF35474.1 - 0.0017 19.2 6.0 0.46 11.3 1.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4744) SMN PF06003.12 OWF35474.1 - 8 5.6 37.9 1.8e+04 -16.6 37.9 3.5 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Lectin_C PF00059.21 OWF35475.1 - 2.1e-13 51.0 1.3 2.1e-13 51.0 1.3 2.0 2 0 0 2 2 2 1 Lectin C-type domain Chordopox_A33R PF05966.12 OWF35475.1 - 0.025 13.9 0.1 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Endonuclease_NS PF01223.23 OWF35477.1 - 0.017 14.9 0.1 0.038 13.8 0.1 1.6 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease Guanylate_kin PF00625.21 OWF35478.1 - 1.1e-37 129.5 2.3 4.9e-28 98.0 0.1 2.5 3 0 0 3 3 3 2 Guanylate kinase VGCC_beta4Aa_N PF12052.8 OWF35478.1 - 9.5e-19 67.2 3.5 9.5e-19 67.2 3.5 2.2 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 OWF35478.1 - 0.032 13.9 0.1 0.088 12.4 0.1 1.8 2 0 0 2 2 2 0 SH3 domain WD40 PF00400.32 OWF35479.1 - 1.3e-29 101.8 29.7 0.00029 21.6 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35479.1 - 1.7e-15 57.1 6.4 0.0004 20.6 0.1 5.7 2 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF35479.1 - 2.5e-06 27.5 6.1 0.095 12.6 0.1 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OWF35479.1 - 0.00011 21.0 10.9 0.035 12.7 0.1 4.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF35479.1 - 0.00034 20.0 0.1 0.28 10.5 0.0 3.3 2 2 2 4 4 4 2 WD40-like domain ELYS-bb PF16687.5 OWF35479.1 - 0.046 12.3 0.1 0.54 8.8 0.0 2.0 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Cytochrom_C552 PF02335.15 OWF35479.1 - 0.059 12.3 1.0 0.09 11.7 1.0 1.2 1 0 0 1 1 1 0 Cytochrome c552 Nucleoporin_N PF08801.11 OWF35479.1 - 0.11 11.2 0.1 11 4.7 0.0 2.7 2 1 0 2 2 2 0 Nup133 N terminal like EF_TS PF00889.19 OWF35480.1 - 3.9e-28 98.5 0.1 7e-28 97.7 0.1 1.4 1 1 0 1 1 1 1 Elongation factor TS SAPS PF04499.15 OWF35480.1 - 0.063 12.1 1.7 0.072 11.9 1.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Guanylate_kin PF00625.21 OWF35481.1 - 2.5e-67 226.1 0.0 2.9e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 OWF35481.1 - 1.4e-06 28.8 0.0 3.2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 OWF35481.1 - 4.1e-05 23.3 0.0 0.0073 16.0 0.0 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 OWF35481.1 - 8.4e-05 22.8 0.0 0.0051 17.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OWF35481.1 - 0.00012 22.1 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OWF35481.1 - 0.00015 21.5 0.1 0.24 11.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 OWF35481.1 - 0.00018 21.2 0.0 0.044 13.4 0.0 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OWF35481.1 - 0.00051 20.6 1.1 0.0037 17.8 0.4 2.4 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 OWF35481.1 - 0.00056 19.0 0.0 0.00084 18.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 OWF35481.1 - 0.00091 19.5 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OWF35481.1 - 0.002 18.0 0.1 0.0071 16.3 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OWF35481.1 - 0.0033 17.2 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF35481.1 - 0.0035 17.9 0.1 0.006 17.1 0.1 1.8 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 OWF35481.1 - 0.0049 17.2 0.1 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 OWF35481.1 - 0.0087 15.6 0.0 0.066 12.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 OWF35481.1 - 0.0097 15.8 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OWF35481.1 - 0.012 15.7 0.0 0.024 14.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF35481.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 OWF35481.1 - 0.022 14.0 0.0 0.079 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) HTH_56 PF18662.1 OWF35481.1 - 0.033 14.2 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Cch helix turn helix domain dNK PF01712.19 OWF35481.1 - 0.062 13.1 0.1 0.68 9.8 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_17 PF13207.6 OWF35481.1 - 0.063 13.7 0.1 0.94 9.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OWF35481.1 - 0.074 12.6 0.2 6.1 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OWF35481.1 - 0.077 13.2 0.1 0.34 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OWF35481.1 - 0.095 12.0 0.3 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Apolipoprotein PF01442.18 OWF35481.1 - 0.12 12.3 1.8 0.17 11.7 1.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Gemini_AL1_M PF08283.11 OWF35481.1 - 0.16 12.1 0.2 2.4 8.3 0.0 2.6 2 1 1 3 3 3 0 Geminivirus rep protein central domain AAA_23 PF13476.6 OWF35481.1 - 0.26 11.8 2.4 0.61 10.6 2.4 1.8 1 1 0 1 1 1 0 AAA domain DUF2870 PF11069.8 OWF35482.1 - 0.37 11.2 8.8 15 6.0 1.7 4.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) NPV_P10 PF05531.12 OWF35483.1 - 1.8 9.1 4.6 21 5.7 0.1 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.12 OWF35483.1 - 2 8.4 7.2 13 5.9 1.5 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat FAP206 PF12018.8 OWF35483.1 - 5.5 6.4 18.2 0.18 11.3 9.1 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF4573 PF15140.6 OWF35484.1 - 6.2e-06 26.1 0.1 7.5e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) DUF3060 PF11259.8 OWF35484.1 - 0.37 10.5 3.3 5.4 6.8 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3060) MFS_1 PF07690.16 OWF35485.1 - 5.9e-38 130.7 35.8 2.7e-30 105.5 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF35485.1 - 9.1e-10 38.4 21.4 4.3e-09 36.1 21.3 1.9 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 OWF35485.1 - 0.0041 16.0 32.2 0.022 13.6 32.2 2.7 1 1 0 1 1 1 1 LacY proton/sugar symporter AAA PF00004.29 OWF35486.1 - 1.2e-56 190.8 0.1 1e-38 132.8 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF35486.1 - 3.4e-10 39.6 0.2 8.4e-10 38.3 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OWF35486.1 - 1.2e-09 38.6 0.3 0.031 14.5 0.0 4.5 3 2 0 3 3 2 2 AAA domain RuvB_N PF05496.12 OWF35486.1 - 1.4e-09 37.9 0.0 0.00033 20.5 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OWF35486.1 - 1.2e-08 35.5 0.0 3.1e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 OWF35486.1 - 7.5e-08 32.7 0.5 0.0002 21.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) CDC48_N PF02359.18 OWF35486.1 - 1.2e-07 31.8 0.0 2.2e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_5 PF07728.14 OWF35486.1 - 1.6e-07 31.4 0.1 0.036 14.0 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OWF35486.1 - 2.3e-06 27.1 0.5 0.026 13.9 0.1 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OWF35486.1 - 3e-06 26.7 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 OWF35486.1 - 3.9e-06 27.2 0.0 0.15 12.5 0.0 3.1 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 OWF35486.1 - 8.3e-06 25.8 0.0 0.077 13.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OWF35486.1 - 1.8e-05 25.3 0.1 0.073 13.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 OWF35486.1 - 3.4e-05 24.0 0.0 0.15 12.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 OWF35486.1 - 5.2e-05 23.1 0.0 0.44 10.3 0.0 3.0 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 OWF35486.1 - 5.8e-05 23.1 0.1 0.024 14.5 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_24 PF13479.6 OWF35486.1 - 0.00011 22.0 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 OWF35486.1 - 0.00014 21.8 0.0 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 OWF35486.1 - 0.00023 20.9 0.9 0.003 17.3 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ABC_tran PF00005.27 OWF35486.1 - 0.00029 21.4 0.2 0.93 10.0 0.1 2.9 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 OWF35486.1 - 0.00039 20.2 0.0 0.33 10.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 OWF35486.1 - 0.0004 19.9 0.0 0.29 10.6 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 OWF35486.1 - 0.00081 19.2 0.5 0.68 9.6 0.1 3.1 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 OWF35486.1 - 0.0014 18.0 0.2 0.15 11.4 0.0 2.7 2 0 0 2 2 2 1 KaiC AAA_17 PF13207.6 OWF35486.1 - 0.0019 18.6 0.3 0.092 13.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 OWF35486.1 - 0.002 17.4 0.0 1.7 7.8 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.6 OWF35486.1 - 0.0026 17.6 0.1 1.4 8.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 OWF35486.1 - 0.0055 16.6 0.0 0.042 13.7 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 OWF35486.1 - 0.0056 15.8 0.0 0.48 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OWF35486.1 - 0.012 15.9 0.0 0.88 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 OWF35486.1 - 0.02 14.4 0.1 7.9 5.8 0.0 2.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 OWF35486.1 - 0.022 14.5 0.0 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase Zeta_toxin PF06414.12 OWF35486.1 - 0.032 13.5 1.0 0.47 9.7 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin Sigma54_activ_2 PF14532.6 OWF35486.1 - 0.041 14.0 0.1 12 6.1 0.0 3.6 4 0 0 4 4 3 0 Sigma-54 interaction domain PhoH PF02562.16 OWF35486.1 - 0.042 13.3 0.2 8 5.8 0.2 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 OWF35486.1 - 0.064 13.6 6.7 2.5 8.4 0.6 3.7 4 1 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 OWF35486.1 - 0.088 12.7 0.0 16 5.3 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 OWF35486.1 - 0.11 12.2 0.2 10 6.0 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 OWF35486.1 - 0.11 12.0 2.5 9.9 5.7 0.4 3.2 4 0 0 4 4 3 0 AAA domain wnt PF00110.19 OWF35487.1 - 7.4e-119 396.9 32.0 9.6e-119 396.5 32.0 1.1 1 0 0 1 1 1 1 wnt family Pentapeptide PF00805.22 OWF35489.1 - 0.018 14.7 0.0 44 3.8 0.0 4.5 5 0 0 5 5 5 0 Pentapeptide repeats (8 copies) z-alpha PF02295.17 OWF35490.1 - 1.2e-09 38.1 0.3 3e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Adenosine deaminase z-alpha domain HTH_11 PF08279.12 OWF35490.1 - 0.0062 16.5 0.1 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 HTH domain HTH_9 PF08221.11 OWF35490.1 - 0.011 15.8 0.1 0.057 13.5 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_IclR PF09339.10 OWF35490.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain TFIIE_beta PF02186.15 OWF35490.1 - 0.13 12.6 0.4 0.85 10.0 0.0 2.3 2 0 0 2 2 2 0 TFIIE beta subunit core domain DEADboxA PF12343.8 OWF35490.1 - 3.8 8.1 40.6 0.34 11.5 9.2 4.3 2 1 1 3 3 3 0 Cold shock protein DEAD box A Pkinase PF00069.25 OWF35491.1 - 2.6e-75 253.2 0.1 2.7e-74 249.9 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35491.1 - 7.5e-42 143.4 0.0 2.4e-41 141.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 OWF35491.1 - 7.2e-10 38.3 0.5 0.44 11.0 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 OWF35491.1 - 5.1e-08 33.2 2.2 5.7e-05 23.4 0.0 4.3 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 OWF35491.1 - 7e-07 29.6 1.0 0.00033 21.1 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat Arm PF00514.23 OWF35491.1 - 3e-06 27.1 0.8 0.085 12.9 0.0 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 OWF35491.1 - 6e-05 23.1 0.0 8.4e-05 22.7 0.2 3.9 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Haspin_kinase PF12330.8 OWF35491.1 - 0.00094 18.2 1.1 0.024 13.6 0.0 3.4 3 1 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 OWF35491.1 - 0.0023 17.3 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF35491.1 - 0.02 13.7 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OWF35491.1 - 0.027 14.4 0.0 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family M11L PF11099.8 OWF35491.1 - 1.3 9.2 4.9 1.3 9.3 0.2 3.0 3 0 0 3 3 3 0 Apoptosis regulator M11L like ATP_bind_1 PF03029.17 OWF35492.1 - 2.7e-82 276.2 0.2 4.8e-82 275.4 0.2 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OWF35492.1 - 2.8e-07 30.3 2.7 9.5e-07 28.5 0.5 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OWF35492.1 - 7.1e-06 25.6 0.3 8.9e-05 22.1 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OWF35492.1 - 1.3e-05 25.2 0.0 0.0011 19.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF35492.1 - 0.00016 22.0 0.0 0.0006 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF35492.1 - 0.00019 21.9 0.2 0.00068 20.1 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 OWF35492.1 - 0.00019 21.1 0.2 0.001 18.7 0.2 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 OWF35492.1 - 0.00038 20.4 0.1 0.0043 17.0 0.1 2.2 1 1 0 1 1 1 1 NTPase NACHT PF05729.12 OWF35492.1 - 0.00043 20.2 0.0 0.001 19.0 0.0 1.6 2 0 0 2 2 1 1 NACHT domain CLP1_P PF16575.5 OWF35492.1 - 0.00063 19.6 0.0 0.02 14.7 0.0 2.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 OWF35492.1 - 0.0013 18.9 0.0 0.0045 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 OWF35492.1 - 0.0014 18.3 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRPRB PF09439.10 OWF35492.1 - 0.0015 18.0 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 OWF35492.1 - 0.0024 17.4 0.0 0.3 10.5 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_24 PF13479.6 OWF35492.1 - 0.0025 17.6 0.1 0.0071 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF87 PF01935.17 OWF35492.1 - 0.003 17.7 1.9 0.085 12.9 0.0 2.5 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_19 PF13245.6 OWF35492.1 - 0.003 17.9 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OWF35492.1 - 0.0042 16.1 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 OWF35492.1 - 0.0044 16.2 0.0 0.01 15.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 OWF35492.1 - 0.0049 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 OWF35492.1 - 0.0058 15.9 0.1 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin Viral_helicase1 PF01443.18 OWF35492.1 - 0.0077 16.0 0.1 0.027 14.2 0.0 2.0 3 0 0 3 3 1 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 OWF35492.1 - 0.0081 16.1 0.0 5.9 6.8 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 OWF35492.1 - 0.011 16.2 3.6 0.022 15.3 0.0 3.1 3 2 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 OWF35492.1 - 0.012 15.4 0.0 0.51 10.1 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 OWF35492.1 - 0.022 14.8 0.4 0.23 11.5 0.1 2.7 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.6 OWF35492.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 OWF35492.1 - 0.032 14.0 0.2 0.13 12.0 0.0 2.1 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 OWF35492.1 - 0.036 14.1 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 OWF35492.1 - 0.037 14.0 0.4 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 OWF35492.1 - 0.043 14.0 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 OWF35492.1 - 0.057 12.7 0.0 0.15 11.2 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_32 PF13654.6 OWF35492.1 - 0.065 12.0 9.5 3.4 6.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Peptidase_M9_N PF08453.10 OWF35492.1 - 0.067 12.9 0.5 0.11 12.2 0.0 1.5 2 0 0 2 2 1 0 Peptidase family M9 N-terminal G-alpha PF00503.20 OWF35492.1 - 0.07 12.3 3.4 0.12 11.5 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit MobB PF03205.14 OWF35492.1 - 0.092 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 OWF35492.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 OWF35492.1 - 0.14 12.2 6.1 9.5 6.2 0.0 4.0 2 1 1 4 4 4 0 Dynamin family Thymidylate_kin PF02223.17 OWF35492.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.6 3 1 0 3 3 2 0 Thymidylate kinase ABC_tran PF00005.27 OWF35492.1 - 0.53 10.8 1.9 2 8.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter CARD PF00619.21 OWF35493.1 - 2.1e-06 27.7 0.3 7e-06 26.0 0.3 2.0 1 0 0 1 1 1 1 Caspase recruitment domain DUF641 PF04859.12 OWF35493.1 - 0.028 14.8 0.1 0.028 14.8 0.1 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.6 OWF35493.1 - 0.18 12.2 23.4 0.16 12.4 0.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) 7tm_1 PF00001.21 OWF35494.1 - 5.7e-13 48.8 28.7 8.1e-13 48.3 28.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF35494.1 - 5.7e-06 26.1 34.1 5.7e-06 26.1 34.1 1.9 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF35494.1 - 0.0002 20.9 36.4 0.00036 20.0 36.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx L_HMGIC_fpl PF10242.9 OWF35495.1 - 3.4e-24 86.1 14.1 4.1e-24 85.8 14.1 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 OWF35495.1 - 0.29 10.9 16.9 1.6 8.4 16.9 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SUI1 PF01253.22 OWF35496.1 - 6.9e-17 61.8 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TatD_DNase PF01026.21 OWF35498.1 - 4.8e-15 55.6 0.1 5.4e-15 55.5 0.1 1.0 1 0 0 1 1 1 1 TatD related DNase Cornifin PF02389.15 OWF35499.1 - 2.1e-06 28.0 4.0 0.00016 21.9 0.0 2.9 1 1 1 2 2 2 1 Cornifin (SPRR) family DUF3432 PF11914.8 OWF35499.1 - 0.4 10.9 33.6 0.93 9.8 0.9 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF3432) DEAD PF00270.29 OWF35500.1 - 6.4e-06 26.0 0.0 8.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OWF35500.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PELOTA_1 PF15608.6 OWF35500.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 2 0 0 2 2 2 0 PELOTA RNA binding domain Lipase_GDSL_2 PF13472.6 OWF35501.1 - 1.3e-05 25.7 0.0 1.8e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DltD PF04914.12 OWF35501.1 - 0.00052 19.5 0.0 0.00066 19.2 0.0 1.1 1 0 0 1 1 1 1 DltD protein Lipase_GDSL PF00657.22 OWF35501.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Muskelin_N PF06588.11 OWF35502.1 - 2.3e-85 285.5 1.1 4.1e-85 284.7 1.1 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 OWF35502.1 - 1.3e-23 82.7 8.7 5.3e-08 33.0 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF35502.1 - 8.6e-20 70.5 3.3 0.00038 20.4 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF35502.1 - 2.6e-19 68.8 5.2 0.0018 18.5 0.1 6.5 8 0 0 8 8 8 5 Kelch motif Kelch_1 PF01344.25 OWF35502.1 - 5.7e-15 54.6 10.0 4.4e-05 23.0 0.1 6.0 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OWF35502.1 - 1.2e-10 41.1 6.9 0.00082 19.3 0.0 6.4 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 OWF35502.1 - 3.8e-08 33.0 6.0 0.016 15.2 0.2 5.2 4 0 0 4 4 4 2 Kelch motif F5_F8_type_C PF00754.25 OWF35502.1 - 0.00014 21.9 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain HigB_toxin PF09907.9 OWF35502.1 - 0.072 13.3 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DNAP_B_exo_N PF08452.10 OWF35502.1 - 0.082 12.3 0.2 0.21 11.0 0.2 1.7 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal dCache_1 PF02743.18 OWF35503.1 - 1.4e-12 48.0 0.3 2.9e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 Cache domain VWA_N PF08399.11 OWF35503.1 - 4.4e-06 27.2 4.7 0.00091 19.7 0.3 3.0 3 0 0 3 3 3 2 VWA N-terminal VWA_2 PF13519.6 OWF35503.1 - 0.00045 20.8 0.0 0.0012 19.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain TMEM154 PF15102.6 OWF35503.1 - 0.0014 18.6 2.7 0.003 17.5 2.7 1.5 1 0 0 1 1 1 1 TMEM154 protein family EVI2A PF05399.11 OWF35503.1 - 0.0098 15.5 3.0 0.02 14.5 3.0 1.4 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Prominin PF05478.11 OWF35503.1 - 0.031 12.3 0.9 0.39 8.6 0.0 2.2 2 0 0 2 2 2 0 Prominin TraL PF07178.11 OWF35503.1 - 0.2 12.2 0.2 0.84 10.1 0.1 2.1 2 0 0 2 2 2 0 TraL protein Podoplanin PF05808.11 OWF35503.1 - 0.84 9.7 5.6 2.2 8.4 5.6 1.7 1 0 0 1 1 1 0 Podoplanin DUF5582 PF17819.1 OWF35504.1 - 1.6e-07 31.9 0.2 2.9e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 OWF35504.1 - 0.0049 16.0 0.0 0.0068 15.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5586) EF-hand_7 PF13499.6 OWF35504.1 - 0.01 16.3 0.1 0.064 13.7 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain pair DUF2151 PF10221.9 OWF35505.1 - 5.5e-67 226.9 0.1 6.5e-67 226.7 0.1 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF2151 PF10221.9 OWF35506.1 - 3.9e-182 607.4 0.0 4.5e-182 607.2 0.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator Fasciclin PF02469.22 OWF35507.1 - 3.3e-50 169.6 0.1 2.1e-27 95.9 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 OWF35508.1 - 2.5e-71 237.9 0.9 2e-34 118.6 0.2 2.0 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 OWF35509.1 - 1.1e-46 158.2 0.6 2.9e-25 88.9 0.1 2.0 2 0 0 2 2 2 2 Fasciclin domain SHD1 PF03983.12 OWF35510.1 - 0.00048 19.9 0.4 14 5.6 0.0 4.1 1 1 4 5 5 5 3 SLA1 homology domain 1, SHD1 Herpes_UL47 PF03362.13 OWF35510.1 - 0.042 12.6 0.0 0.15 10.8 0.0 1.7 1 1 0 1 1 1 0 Herpesvirus UL47 protein PilI PF10623.9 OWF35510.1 - 0.046 13.9 1.2 3.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Plasmid conjugative transfer protein PilI PBSX_XtrA PF17356.2 OWF35510.1 - 0.16 11.9 0.0 45 4.1 0.0 2.9 3 0 0 3 3 3 0 Phage-like element PBSX protein XtrA Clathrin-link PF09268.10 OWF35510.1 - 0.17 11.3 0.0 23 4.5 0.0 2.4 2 0 0 2 2 2 0 Clathrin, heavy-chain linker GTP_EFTU PF00009.27 OWF35511.1 - 4.9e-57 192.6 1.1 6.6e-57 192.2 0.5 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OWF35511.1 - 3.5e-14 53.0 0.0 8.5e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OWF35511.1 - 6.9e-12 45.6 0.9 1.3e-11 44.7 0.9 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF35511.1 - 5.2e-05 23.3 0.4 0.00011 22.3 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OWF35511.1 - 0.082 12.6 0.4 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.23 OWF35511.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Guanylate_kin PF00625.21 OWF35512.1 - 8.7e-36 123.3 0.0 1.9e-35 122.2 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.7 OWF35512.1 - 3.1e-18 65.5 25.5 5.8e-05 23.4 0.8 5.6 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF35512.1 - 2.4e-16 59.7 13.9 6.6e-12 45.3 5.6 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 OWF35512.1 - 5.8e-12 45.2 23.8 1.3e-05 24.8 4.1 4.9 1 1 5 6 6 6 6 Leucine rich repeat LRR_6 PF13516.6 OWF35512.1 - 3.4e-05 23.5 17.0 3.5 7.9 0.0 8.0 9 0 0 9 9 9 2 Leucine Rich repeat Ectoine_synth PF06339.12 OWF35512.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Ectoine synthase Smoothelin PF12510.8 OWF35512.1 - 0.22 11.6 1.7 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein MRP-S33 PF08293.11 OWF35513.1 - 6.2e-14 52.0 0.2 7.3e-14 51.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 TAT_ubiq PF07706.12 OWF35513.1 - 1.4 9.2 3.9 7.1 6.9 1.5 2.6 2 1 0 2 2 2 0 Aminotransferase ubiquitination site DRMBL PF07522.14 OWF35514.1 - 7.6e-12 45.4 0.4 3.9e-11 43.1 0.4 2.2 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OWF35514.1 - 1.7e-07 31.0 0.5 6e-07 29.2 0.1 2.1 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.12 OWF35514.1 - 2.3e-05 24.2 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DUF4735 PF15882.5 OWF35514.1 - 1.4 8.3 6.2 1.7 8.0 5.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) Herpes_gE PF02480.16 OWF35515.1 - 4.6e-05 22.3 0.2 9.5e-05 21.3 0.2 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 OWF35515.1 - 0.00026 20.9 1.8 0.00026 20.9 1.8 3.9 2 1 2 4 4 4 1 TMEM154 protein family EphA2_TM PF14575.6 OWF35515.1 - 0.0031 18.3 0.1 0.021 15.7 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 OWF35516.1 - 0.00024 21.8 2.0 0.0022 18.6 0.0 2.6 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 OWF35516.1 - 0.0038 17.1 1.6 0.012 15.5 1.6 1.9 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 OWF35516.1 - 0.014 16.3 0.7 0.17 12.8 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 OWF35516.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein FAM176 PF14851.6 OWF35516.1 - 0.088 12.5 3.8 1 9.0 0.0 2.5 2 0 0 2 2 2 0 FAM176 family Coq4 PF05019.13 OWF35517.1 - 5.6 6.2 50.4 71 2.6 0.0 17.5 5 3 19 25 25 25 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Cu-oxidase_3 PF07732.15 OWF35518.1 - 4.4e-39 133.2 1.6 8.8e-37 125.7 0.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF35518.1 - 1.8e-36 124.9 2.2 5e-32 110.5 0.2 4.1 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF35518.1 - 1.3e-27 96.9 0.0 5.2e-24 85.2 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OWF35519.1 - 2.9e-41 140.2 0.1 1.4e-40 138.0 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF35519.1 - 1.7e-35 121.7 2.9 8.4e-29 100.1 0.3 4.5 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF35519.1 - 2.3e-30 105.8 0.8 2.3e-29 102.5 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase DUF202 PF02656.15 OWF35520.1 - 0.011 16.1 0.3 0.022 15.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PepSY_TM PF03929.16 OWF35520.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF3377 PF11857.8 OWF35520.1 - 0.041 13.8 0.2 0.088 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM214 PF10151.9 OWF35521.1 - 2.5e-157 525.2 11.2 2.9e-157 525.0 11.2 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator TAF6_C PF07571.13 OWF35521.1 - 0.017 15.4 0.3 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain STAR_dimer PF16544.5 OWF35521.1 - 0.03 13.9 0.0 0.092 12.3 0.0 1.8 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein DUF4405 PF14358.6 OWF35521.1 - 0.16 12.5 2.4 0.45 11.1 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) PDZ PF00595.24 OWF35522.1 - 4.6e-07 30.1 0.0 8.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain tRNA-synt_2d PF01409.20 OWF35523.1 - 3.8e-89 298.4 0.0 5.4e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OWF35523.1 - 7.2e-21 74.2 1.0 7.2e-21 74.2 1.0 3.4 4 0 0 4 4 4 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 OWF35523.1 - 1e-20 73.2 0.2 3.5e-20 71.5 0.3 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 OWF35523.1 - 2.9e-08 33.4 0.0 0.0001 21.8 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 OWF35523.1 - 6.8e-08 32.4 0.6 1.8e-07 31.0 0.6 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 OWF35523.1 - 0.00042 20.3 0.0 0.00075 19.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 OWF35523.1 - 0.0013 17.9 0.0 0.0033 16.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RPA_C PF08784.11 OWF35523.1 - 0.079 13.6 0.1 0.19 12.4 0.1 1.6 1 0 0 1 1 1 0 Replication protein A C terminal B-block_TFIIIC PF04182.12 OWF35523.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Acyl-CoA_dh_N PF02771.16 OWF35524.1 - 4.7e-23 82.0 0.0 1e-22 80.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OWF35524.1 - 5.1e-21 75.5 0.0 8e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OWF35524.1 - 2.6e-19 69.2 0.0 4.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF35524.1 - 9.5e-07 29.2 0.0 2.9e-05 24.3 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M1 PF01433.20 OWF35525.1 - 9e-10 38.5 0.8 2.3e-09 37.2 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain HEAT_2 PF13646.6 OWF35525.1 - 3.4e-05 24.1 0.0 0.028 14.8 0.0 3.1 2 1 0 3 3 3 1 HEAT repeats Peptidase_M1_N PF17900.1 OWF35525.1 - 6.8e-05 23.1 0.1 0.00019 21.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain TSGP1 PF07771.11 OWF35525.1 - 0.28 11.4 5.3 0.77 9.9 5.3 1.8 1 0 0 1 1 1 0 Tick salivary peptide group 1 ArfGap PF01412.18 OWF35526.1 - 4.3e-32 110.6 0.3 4.3e-32 110.6 0.3 2.4 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf HLH PF00010.26 OWF35527.1 - 7.3e-14 51.5 1.0 1.1e-13 50.9 0.5 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain YL1 PF05764.13 OWF35527.1 - 0.0057 16.8 4.4 0.0087 16.2 4.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein DUF5123 PF17161.4 OWF35527.1 - 0.11 13.6 3.3 0.21 12.7 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5123) TPMT PF05724.11 OWF35528.1 - 1.1e-52 178.9 0.1 1.2e-52 178.7 0.1 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OWF35528.1 - 0.0051 17.5 0.0 0.038 14.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF35528.1 - 0.0059 17.2 0.0 0.016 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain 7tm_1 PF00001.21 OWF35529.1 - 3.2e-32 111.9 13.9 4.1e-32 111.6 13.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF35529.1 - 4.5e-10 39.6 18.2 6.4e-10 39.1 18.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF35529.1 - 0.0016 17.9 14.9 0.0043 16.5 14.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 OWF35529.1 - 0.036 13.9 11.2 0.044 13.6 10.5 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Pkinase PF00069.25 OWF35530.1 - 2e-23 83.1 0.0 4.7e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35530.1 - 3.8e-18 65.7 0.0 8.9e-18 64.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.23 OWF35530.1 - 3.7e-07 30.4 2.0 8.9e-07 29.1 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF35530.1 - 0.00038 20.5 0.0 0.0029 17.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase CNOT1_HEAT PF16418.5 OWF35530.1 - 0.035 14.2 0.2 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Kdo PF06293.14 OWF35530.1 - 0.044 13.1 0.0 0.15 11.4 0.0 1.9 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RecQ5 PF06959.11 OWF35530.1 - 0.06 13.3 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) Dynactin_p22 PF07426.11 OWF35530.1 - 0.15 11.9 8.5 0.18 11.6 6.9 1.9 2 0 0 2 2 2 0 Dynactin subunit p22 Fib_alpha PF08702.10 OWF35530.1 - 6.8 6.9 12.1 26 5.0 5.3 3.2 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 OWF35531.1 - 2.2e-23 83.0 0.0 2.1e-22 79.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35531.1 - 2.4e-21 76.2 0.7 2.9e-20 72.6 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Dynamin_N PF00350.23 OWF35531.1 - 1.4e-10 41.5 0.0 4.6e-09 36.6 0.0 3.2 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF35531.1 - 3.4e-07 30.3 0.0 1.3e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4238 PF14022.6 OWF35531.1 - 0.18 11.3 4.0 0.36 10.3 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) HEPN_Apea PF18739.1 OWF35531.1 - 7.2 7.1 7.9 12 6.4 1.4 3.2 2 1 1 3 3 3 0 Apea-like HEPN Kinesin PF00225.23 OWF35532.1 - 1.2e-95 320.3 0.4 2.1e-95 319.5 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF35532.1 - 4.4e-14 52.7 1.9 6.3e-14 52.2 0.2 2.2 2 0 0 2 2 2 1 Microtubule binding Type2_restr_D3 PF16902.5 OWF35532.1 - 0.072 13.0 4.1 0.21 11.5 0.0 2.9 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Herpes_DNAp_acc PF04929.12 OWF35532.1 - 0.93 8.4 7.0 1.9 7.4 7.0 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Fib_alpha PF08702.10 OWF35532.1 - 1.1 9.5 7.0 3.2 7.9 7.0 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cys_Met_Meta_PP PF01053.20 OWF35533.1 - 9.3e-154 511.6 0.0 1e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 OWF35533.1 - 1.4e-07 30.4 0.1 9.9e-07 27.6 0.1 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 OWF35533.1 - 0.0003 20.1 0.1 0.00042 19.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OWF35533.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ASXH PF13919.6 OWF35534.1 - 2.8e-41 140.8 1.0 8.8e-41 139.2 1.0 2.0 1 0 0 1 1 1 1 Asx homology domain PHD_3 PF13922.6 OWF35534.1 - 1.2e-19 70.4 14.1 1.2e-19 70.4 14.1 4.3 3 1 2 5 5 5 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.13 OWF35534.1 - 1.3e-14 54.3 0.0 7.2e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain DUF2052 PF09747.9 OWF35534.1 - 2.5 8.2 7.3 0.36 10.9 1.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4523 PF15023.6 OWF35536.1 - 3.9e-12 46.3 0.6 7.3e-12 45.4 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_1 PF00076.22 OWF35536.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase PF00102.27 OWF35537.1 - 1.8e-138 459.8 6.4 1.3e-75 254.0 0.2 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 OWF35537.1 - 6.3e-39 132.2 7.1 3.6e-15 56.1 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Kringle PF00051.18 OWF35537.1 - 4.3e-18 65.4 8.2 1.1e-17 64.1 8.2 1.7 1 0 0 1 1 1 1 Kringle domain Pur_ac_phosph_N PF16656.5 OWF35537.1 - 5.2e-12 46.2 0.6 0.024 15.2 0.1 4.8 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF35537.1 - 1.2e-08 35.2 0.1 4.1e-05 23.8 0.2 3.7 4 0 0 4 4 3 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 OWF35537.1 - 1.5e-05 24.8 0.0 0.086 12.7 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF35537.1 - 0.00036 20.6 0.0 0.069 13.1 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Ig_3 PF13927.6 OWF35537.1 - 0.0012 19.4 0.3 0.0061 17.1 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain PTP_tm PF18861.1 OWF35537.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J ASFV_J13L PF05568.11 OWF35537.1 - 0.066 13.0 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 African swine fever virus J13L protein SusE PF14292.6 OWF35537.1 - 0.09 13.0 0.2 0.44 10.8 0.1 2.2 2 0 0 2 2 2 0 SusE outer membrane protein DUF4381 PF14316.6 OWF35537.1 - 0.12 12.6 0.4 1.6 9.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 OWF35537.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family AAA_12 PF13087.6 OWF35538.1 - 1.2e-28 100.1 0.1 1.5e-28 99.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OWF35538.1 - 0.00033 20.4 0.1 0.07 13.0 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OWF35538.1 - 0.00076 19.3 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 OWF35538.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain MT PF12777.7 OWF35539.1 - 0.0033 16.5 0.1 0.0061 15.6 0.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF2457 PF10446.9 OWF35539.1 - 4.6 6.3 10.3 7.3 5.6 8.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2457) Transglut_core PF01841.19 OWF35540.1 - 2.8e-06 27.7 0.1 4.9e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 Transglutaminase-like superfamily Ank_2 PF12796.7 OWF35541.1 - 5.9e-50 167.8 2.7 9.9e-13 48.5 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF35541.1 - 1.2e-47 159.3 12.6 1e-10 41.6 0.1 6.5 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF35541.1 - 5.8e-46 154.3 4.5 2.1e-09 37.7 0.0 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF35541.1 - 1.7e-37 126.2 9.3 2.9e-08 33.8 0.1 8.1 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 OWF35541.1 - 3e-37 122.4 2.9 0.00014 22.0 0.0 8.6 9 0 0 9 9 9 7 Ankyrin repeat SOCS_box PF07525.16 OWF35541.1 - 3.7e-07 30.4 0.6 3.7e-07 30.4 0.6 1.9 2 0 0 2 2 2 1 SOCS box Nucleotid_trans PF03407.16 OWF35541.1 - 0.13 12.2 0.1 10 6.0 0.0 3.0 3 1 1 4 4 4 0 Nucleotide-diphospho-sugar transferase Synaptonemal_3 PF15191.6 OWF35542.1 - 4.1e-05 23.3 0.8 6.3e-05 22.7 0.8 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 SIP1 PF04938.12 OWF35542.1 - 0.0091 15.7 0.7 0.012 15.4 0.7 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) WD-3 PF09765.9 OWF35542.1 - 0.019 14.3 0.6 0.021 14.1 0.6 1.1 1 0 0 1 1 1 0 WD-repeat region ADK PF00406.22 OWF35543.1 - 1e-39 136.1 0.0 1.2e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 OWF35543.1 - 6.7e-16 58.0 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 OWF35543.1 - 7.2e-11 42.7 0.0 3.6e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain CPL PF08144.11 OWF35544.1 - 3.5e-42 144.2 0.1 3.5e-42 144.2 0.1 4.5 4 2 0 4 4 4 1 CPL (NUC119) domain IFRD PF05004.13 OWF35544.1 - 0.01 15.0 2.1 0.28 10.2 0.2 2.6 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) CRISPR_Cas2 PF09827.9 OWF35544.1 - 0.23 11.7 3.1 0.3 11.3 0.2 2.8 3 0 0 3 3 3 0 CRISPR associated protein Cas2 ABC_tran PF00005.27 OWF35545.1 - 1.1e-23 84.2 0.0 2.8e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF35545.1 - 3.8e-11 43.3 0.0 1.3e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 OWF35545.1 - 0.00073 20.2 0.0 0.0016 19.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) Rad17 PF03215.15 OWF35545.1 - 0.1 12.5 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Dus PF01207.17 OWF35545.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Mpv17_PMP22 PF04117.12 OWF35546.1 - 7.9e-26 90.1 1.4 1.3e-25 89.4 1.4 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family ABC2_membrane_3 PF12698.7 OWF35548.1 - 8.4e-58 196.1 35.6 4e-38 131.4 12.5 3.5 3 0 0 3 3 3 3 ABC-2 family transporter protein ABC_tran PF00005.27 OWF35548.1 - 5e-55 185.8 0.0 1e-30 107.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OWF35548.1 - 1.6e-21 77.5 0.1 7.6e-07 29.2 0.0 4.6 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 OWF35548.1 - 3e-05 24.6 0.5 0.067 13.9 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) AAA_15 PF13175.6 OWF35548.1 - 0.0005 19.9 3.3 1.9 8.1 0.0 4.6 7 0 0 7 7 7 2 AAA ATPase domain ABC2_membrane_2 PF12679.7 OWF35548.1 - 0.0017 17.7 9.1 0.0017 17.7 9.1 2.8 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.6 OWF35548.1 - 0.046 13.5 1.9 0.43 10.4 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 OWF35548.1 - 0.063 12.9 2.8 6.7 6.3 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 OWF35548.1 - 0.42 11.1 12.7 0.13 12.8 0.4 3.4 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 OWF35548.1 - 0.64 9.9 2.2 5 7.0 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase PAC3 PF10178.9 OWF35550.1 - 0.14 12.3 0.0 8.7 6.6 0.0 2.9 2 1 2 4 4 4 0 Proteasome assembly chaperone 3 zf-H2C2_5 PF13909.6 OWF35551.1 - 0.018 14.8 0.4 0.018 14.8 0.4 10.5 10 1 0 10 10 10 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 OWF35551.1 - 0.15 11.8 0.0 0.15 11.8 0.0 9.8 9 2 2 11 11 11 0 Zinc-fingers and homeoboxes C2H2 finger domain DNA_primase_lrg PF04104.14 OWF35552.1 - 2e-88 296.3 0.6 3.5e-88 295.5 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit LMBR1 PF04791.16 OWF35553.1 - 2.7e-26 92.6 20.7 5.3e-24 85.0 5.5 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF4307 PF14155.6 OWF35553.1 - 0.026 14.4 0.7 17 5.3 0.0 4.6 5 1 0 5 5 5 0 Domain of unknown function (DUF4307) DUF2207 PF09972.9 OWF35553.1 - 0.22 10.2 16.9 0.15 10.8 1.1 3.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 OWF35553.1 - 2 8.5 0.0 2 8.5 0.0 5.0 6 1 0 6 6 6 0 Putative Actinobacterial Holin-X, holin superfamily III I-set PF07679.16 OWF35554.1 - 6.8e-17 61.3 0.4 2.7e-08 33.8 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF35554.1 - 1.7e-16 60.6 3.7 6.2e-08 33.1 0.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 OWF35554.1 - 3.3e-10 40.0 1.7 0.0006 19.9 0.8 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF35554.1 - 1.9e-09 37.7 6.3 1e-06 28.9 0.5 2.6 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF35554.1 - 3.1e-09 37.0 5.6 3.6e-05 23.9 0.9 3.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF35554.1 - 1.4e-06 28.3 0.1 4.5e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 OWF35554.1 - 2.3e-06 27.9 0.8 0.033 14.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_4 PF16680.5 OWF35554.1 - 0.016 15.5 0.8 5.4 7.3 0.1 3.6 2 2 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Tim17 PF02466.19 OWF35555.1 - 0.016 15.6 6.8 0.046 14.1 6.8 1.8 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family SARAF PF06682.12 OWF35556.1 - 1.2e-88 298.0 8.8 1.4e-88 297.7 8.8 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RNase_T PF00929.24 OWF35558.1 - 3.6e-33 115.5 0.1 4.1e-33 115.3 0.1 1.0 1 0 0 1 1 1 1 Exonuclease Herpes_UL14 PF03580.14 OWF35558.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF3480 PF11979.8 OWF35559.1 - 8e-167 554.6 0.0 1.4e-166 553.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.21 OWF35559.1 - 1.3e-19 70.1 12.1 2.7e-19 69.1 12.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger SARA PF11409.8 OWF35559.1 - 8e-16 58.0 15.1 2.5e-15 56.4 15.1 2.0 1 0 0 1 1 1 1 Smad anchor for receptor activation (SARA) DUF5403 PF17395.2 OWF35559.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5403) zf_C2HC_14 PF18574.1 OWF35559.1 - 0.12 12.2 7.4 0.05 13.4 2.6 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain PPTA PF01239.22 OWF35560.1 - 2.7e-40 135.0 11.5 2.5e-09 36.5 0.2 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat RabGGT_insert PF07711.11 OWF35560.1 - 4.4e-15 56.0 0.2 1.2e-14 54.6 0.2 1.8 1 0 0 1 1 1 1 Rab geranylgeranyl transferase alpha-subunit, insert domain LRR_4 PF12799.7 OWF35560.1 - 1.1e-06 28.8 6.5 4.1e-05 23.8 2.9 3.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF35560.1 - 2.4e-05 24.0 5.2 0.00014 21.6 3.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 OWF35560.1 - 0.00021 20.8 2.8 0.0005 19.6 1.4 2.2 2 0 0 2 2 2 1 Leucine-rich repeat DUF1505 PF07403.11 OWF35560.1 - 0.09 13.0 0.7 0.21 11.8 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) LRR_6 PF13516.6 OWF35560.1 - 5.3 7.4 7.2 37 4.7 1.2 3.8 4 0 0 4 4 4 0 Leucine Rich repeat AP_endonuc_2 PF01261.24 OWF35561.1 - 1.7e-30 106.0 0.0 2.1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Rad33 PF08730.10 OWF35561.1 - 0.024 14.6 0.2 0.038 14.0 0.2 1.3 1 0 0 1 1 1 0 Rad33 XPC-binding PF09280.11 OWF35562.1 - 9.2e-25 86.2 14.6 1.5e-24 85.5 14.6 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 OWF35562.1 - 4.1e-24 84.1 6.0 9.7e-13 47.7 0.2 2.6 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 OWF35562.1 - 7.2e-22 76.9 1.1 1.2e-21 76.2 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OWF35562.1 - 6.1e-06 26.0 1.5 1.1e-05 25.1 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OWF35562.1 - 0.00013 22.0 0.1 0.00026 21.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 OWF35562.1 - 0.0011 18.8 0.1 0.051 13.4 0.0 2.9 3 0 0 3 3 3 1 Fungal ubiquitin-associated domain CUE PF02845.16 OWF35562.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 CUE domain DUF2870 PF11069.8 OWF35562.1 - 0.11 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2407 PF10302.9 OWF35562.1 - 0.18 12.4 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OWF35562.1 - 0.63 10.1 2.6 6.2 6.9 2.6 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain TRM13 PF05206.14 OWF35563.1 - 3.6e-80 269.2 0.6 2.4e-78 263.3 0.6 2.1 1 1 0 1 1 1 1 Methyltransferase TRM13 POX PF07526.11 OWF35563.1 - 0.03 14.9 2.4 2.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Associated with HOX DnaJ PF00226.31 OWF35564.1 - 2.7e-08 33.8 0.2 8.3e-08 32.3 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain LRR_9 PF14580.6 OWF35565.1 - 5.4e-07 29.3 0.0 2.3e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OWF35565.1 - 6.5e-07 29.0 2.9 0.0073 16.0 0.9 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF35565.1 - 3.2e-06 27.4 10.6 0.00021 21.6 0.7 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) RPAP1_C PF08620.10 OWF35565.1 - 0.017 15.2 0.3 0.054 13.6 0.3 1.8 1 0 0 1 1 1 0 RPAP1-like, C-terminal HLH PF00010.26 OWF35566.1 - 4.5e-16 58.6 1.7 7.4e-16 57.9 1.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC106 PF15794.5 OWF35566.1 - 0.077 12.7 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3094 PF11293.8 OWF35567.1 - 0.21 11.3 0.6 0.51 10.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Xan_ur_permease PF00860.20 OWF35568.1 - 2.1e-78 263.7 28.7 3.3e-78 263.1 28.7 1.3 1 1 0 1 1 1 1 Permease family LapA_dom PF06305.11 OWF35568.1 - 0.46 10.3 3.3 0.4 10.5 0.2 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Cucumo_2B PF03263.13 OWF35569.1 - 9.4e-05 22.8 0.2 50 4.4 0.0 5.4 2 2 4 6 6 6 2 Cucumovirus protein 2B DUF282 PF03380.14 OWF35569.1 - 6.5 6.8 16.5 69 3.5 0.3 5.6 5 0 0 5 5 5 0 Caenorhabditis protein of unknown function, DUF282 FPN1 PF06963.12 OWF35570.1 - 3.1e-140 467.6 8.2 4.2e-140 467.2 8.2 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) OAD_gamma PF04277.13 OWF35570.1 - 0.18 12.4 3.3 1.5 9.5 0.1 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain I-set PF07679.16 OWF35571.1 - 2.8e-32 110.6 0.2 1.5e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF35571.1 - 1.5e-27 96.0 8.4 1.1e-14 54.8 0.0 3.3 3 0 0 3 3 2 2 Immunoglobulin domain ig PF00047.25 OWF35571.1 - 1.3e-21 76.6 0.9 1.1e-11 44.7 0.0 3.6 4 0 0 4 4 3 2 Immunoglobulin domain Ig_2 PF13895.6 OWF35571.1 - 1.6e-20 73.2 0.1 1.3e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF35571.1 - 1.7e-10 41.0 9.8 0.00025 21.2 0.1 4.7 3 2 1 4 4 3 2 Immunoglobulin V-set domain SR-25 PF10500.9 OWF35571.1 - 8.5e-05 22.3 11.9 8.5e-05 22.3 11.9 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Ig_5 PF16681.5 OWF35571.1 - 0.00058 20.2 7.2 0.0048 17.3 0.0 3.4 3 0 0 3 3 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 OWF35571.1 - 0.0006 19.8 10.7 0.0048 16.9 0.0 3.4 3 0 0 3 3 2 2 CD80-like C2-set immunoglobulin domain AP3D1 PF06375.11 OWF35571.1 - 0.0012 19.1 10.1 0.0012 19.1 10.1 2.1 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 Ig_6 PF18452.1 OWF35571.1 - 0.0015 18.0 0.1 0.54 9.9 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain eIF3_subunit PF08597.10 OWF35571.1 - 0.0034 17.3 12.7 0.0034 17.3 12.7 1.5 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit Hamartin PF04388.12 OWF35571.1 - 0.012 14.4 14.0 0.016 13.9 14.0 1.1 1 0 0 1 1 1 0 Hamartin protein SprA-related PF12118.8 OWF35571.1 - 0.014 14.6 7.0 0.024 13.8 7.0 1.4 1 0 0 1 1 1 0 SprA-related family Med13_C PF06333.12 OWF35571.1 - 0.12 11.6 11.0 0.27 10.5 11.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain CDC45 PF02724.14 OWF35571.1 - 0.17 10.2 9.3 0.25 9.6 9.3 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 OWF35571.1 - 0.23 11.5 18.4 0.04 14.0 14.0 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 TCP PF03634.13 OWF35571.1 - 0.9 10.1 15.9 0.13 12.8 11.5 1.8 2 0 0 2 2 1 0 TCP family transcription factor TMEM214 PF10151.9 OWF35571.1 - 0.99 7.8 12.6 1.5 7.2 12.6 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator NUDE_C PF04880.13 OWF35571.1 - 1.3 9.5 14.6 2.7 8.4 14.6 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Apis_Csd PF11671.8 OWF35571.1 - 2.3 8.2 15.5 11 6.0 13.6 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein RR_TM4-6 PF06459.12 OWF35571.1 - 3.7 7.3 13.4 8.5 6.1 13.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 OWF35571.1 - 4.8 6.0 15.1 7.3 5.4 15.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3464 PF11947.8 OWF35571.1 - 5.1 6.8 13.7 15 5.3 13.7 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF1445 PF07286.12 OWF35572.1 - 1.3e-08 34.8 11.9 3.7 7.5 0.0 8.7 2 2 7 9 9 9 6 Protein of unknown function (DUF1445) ATP-synt_Z PF16594.5 OWF35572.1 - 0.00014 21.2 46.5 8 6.0 0.1 12.7 3 3 8 15 15 15 10 Putative AtpZ or ATP-synthase-associated RnlA_toxin PF15935.5 OWF35572.1 - 0.0039 17.0 10.5 7.3 6.3 0.2 7.2 2 2 7 9 9 9 1 RNase LS, bacterial toxin PMEI PF04043.15 OWF35573.1 - 0.039 14.3 0.1 0.046 14.1 0.1 1.3 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Vinculin PF01044.19 OWF35574.1 - 0.13 10.5 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Vinculin family Helicase_C PF00271.31 OWF35575.1 - 3e-18 66.2 0.2 8.7e-18 64.7 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF35575.1 - 4.3e-14 52.7 0.0 1.3e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OWF35575.1 - 1e-05 25.6 0.0 4.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ApoL PF05461.11 OWF35576.1 - 4.2e-10 39.4 7.1 1e-08 34.9 7.1 2.1 1 1 0 1 1 1 1 Apolipoprotein L Borrelia_P13 PF05628.12 OWF35576.1 - 0.13 12.2 2.7 0.26 11.2 2.7 1.4 1 0 0 1 1 1 0 Borrelia membrane protein P13 zf-C2H2_4 PF13894.6 OWF35577.1 - 0.022 15.6 28.3 0.47 11.4 0.3 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF35577.1 - 0.024 14.9 0.7 0.11 12.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OWF35577.1 - 0.058 13.2 24.5 0.13 12.1 3.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OWF35577.1 - 0.068 13.6 21.0 3.1 8.4 0.2 5.9 6 0 0 6 6 6 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 OWF35577.1 - 0.15 11.7 10.5 0.63 9.7 0.3 3.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 OWF35577.1 - 2 9.1 10.9 2.2 9.0 0.8 3.2 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats FAM196 PF15265.6 OWF35577.1 - 2.9 7.3 12.5 0.071 12.6 4.7 1.9 2 0 0 2 2 2 0 FAM196 family CpXC PF14353.6 OWF35577.1 - 4.3 7.4 8.6 1.8 8.6 0.4 3.1 2 1 1 3 3 3 0 CpXC protein zf-C2H2_2 PF12756.7 OWF35577.1 - 8.5 6.8 12.7 16 5.9 0.2 3.7 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) HAUS-augmin3 PF14932.6 OWF35578.1 - 0.0055 16.3 1.6 0.0055 16.3 1.6 3.0 1 1 2 3 3 3 1 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 OWF35578.1 - 0.18 11.6 17.2 0.72 9.6 4.8 2.8 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 OWF35578.1 - 0.6 10.2 17.4 0.69 10.0 0.3 3.8 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 OWF35578.1 - 1.9 8.5 10.7 6 6.9 1.2 3.2 2 1 1 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 OWF35578.1 - 3.7 7.9 11.8 1.5 9.1 1.8 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fungal_TACC PF12709.7 OWF35578.1 - 6.5 7.3 7.3 4.8 7.7 0.1 3.5 3 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF724 PF05266.14 OWF35578.1 - 6.9 6.4 15.8 3.5 7.4 4.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Cadherin PF00028.17 OWF35580.1 - 5.5e-97 318.4 15.7 7.8e-20 71.1 0.1 7.5 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF35580.1 - 1.1e-10 41.2 0.0 1.2e-08 34.7 0.0 3.4 2 0 0 2 2 2 1 Cadherin-like Cadherin_3 PF16184.5 OWF35580.1 - 3e-05 24.0 15.2 0.095 12.7 0.1 6.6 7 0 0 7 7 7 2 Cadherin-like Cadherin_4 PF17803.1 OWF35580.1 - 0.0017 19.0 30.3 0.094 13.3 1.0 6.6 6 0 0 6 6 6 3 Bacterial cadherin-like domain Staphylokinase PF02821.16 OWF35580.1 - 0.067 13.6 1.9 0.22 12.0 1.9 1.9 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family Cadherin_C_2 PF16492.5 OWF35580.1 - 0.11 13.2 0.0 0.44 11.3 0.0 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 OWF35580.1 - 0.19 12.0 2.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MIT_C PF16565.5 OWF35581.1 - 1.6e-57 193.4 0.2 1.6e-57 193.4 0.2 1.6 2 0 0 2 2 2 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 OWF35581.1 - 1.2e-16 60.5 0.2 2.4e-16 59.5 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF5327 PF17261.2 OWF35581.1 - 0.11 13.2 0.5 12 6.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) CMD PF02627.20 OWF35581.1 - 0.12 12.4 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family MGS PF02142.22 OWF35581.1 - 0.13 12.4 0.6 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 MGS-like domain F-box-like PF12937.7 OWF35582.1 - 1e-07 31.7 0.3 2.5e-07 30.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF35582.1 - 0.00016 21.4 0.2 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain GDA1_CD39 PF01150.17 OWF35583.1 - 1.3e-71 241.5 0.0 1.8e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Hydantoinase_A PF01968.18 OWF35583.1 - 0.14 11.4 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Ppx-GppA PF02541.16 OWF35583.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family ATG101 PF07855.12 OWF35584.1 - 4.7e-40 137.1 0.0 6.6e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 RhoGAP PF00620.27 OWF35585.1 - 5.1e-39 133.5 0.0 1.1e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OWF35585.1 - 3.6e-36 123.8 5.4 1.1e-12 48.4 0.1 5.8 5 0 0 5 5 5 5 PH domain ArfGap PF01412.18 OWF35585.1 - 3.9e-35 120.4 2.8 8.8e-35 119.3 2.8 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAM_1 PF00536.30 OWF35585.1 - 1.5e-12 47.8 0.1 4.7e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF35585.1 - 5.9e-11 42.3 0.1 1.3e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OWF35585.1 - 2.1e-09 37.9 0.0 7.4e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_11 PF15413.6 OWF35585.1 - 1.6e-08 34.9 15.0 0.0016 18.8 3.1 5.5 6 1 0 6 6 6 2 Pleckstrin homology domain PH_8 PF15409.6 OWF35585.1 - 1.3e-05 25.4 6.5 0.0062 16.8 0.2 4.2 5 0 0 5 5 5 2 Pleckstrin homology domain PH_3 PF14593.6 OWF35585.1 - 0.00035 20.6 0.2 0.0045 17.1 0.1 2.8 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 OWF35585.1 - 0.028 14.3 0.1 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 OWF35585.1 - 0.13 12.7 0.2 3.3 8.1 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain PH_16 PF17838.1 OWF35585.1 - 0.19 11.6 0.3 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 PH domain BPL_N PF09825.9 OWF35586.1 - 8.4e-61 206.1 0.0 1e-60 205.8 0.0 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_N PF09825.9 OWF35587.1 - 1.2e-49 169.3 0.0 1.5e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal PTP_tm PF18861.1 OWF35588.1 - 0.0033 17.4 0.1 0.0047 16.9 0.1 1.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Shisa PF13908.6 OWF35588.1 - 0.0065 16.7 0.0 0.0081 16.4 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF35588.1 - 0.025 15.4 0.0 0.031 15.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Romo1 PF10247.9 OWF35588.1 - 0.033 14.6 0.1 0.054 13.9 0.1 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 PAP2_3 PF14378.6 OWF35588.1 - 0.041 13.6 0.5 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 PAP2 superfamily Amnionless PF14828.6 OWF35588.1 - 0.052 12.4 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF3611 PF12263.8 OWF35588.1 - 0.08 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF4381 PF14316.6 OWF35588.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Vpu PF00558.19 OWF35588.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Vpu protein LapA_dom PF06305.11 OWF35588.1 - 0.25 11.2 0.2 0.43 10.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RR_TM4-6 PF06459.12 OWF35589.1 - 0.61 9.9 18.5 0.64 9.8 18.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OWF35589.1 - 1 8.0 14.8 1.1 7.9 14.8 1.0 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 OWF35589.1 - 2.1 7.0 12.4 2.2 6.9 12.4 1.0 1 0 0 1 1 1 0 Raftlin DUF4603 PF15376.6 OWF35589.1 - 5.6 4.2 17.4 6.1 4.1 17.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) KAP_NTPase PF07693.14 OWF35590.1 - 3.7e-76 256.5 0.0 5.5e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.7 OWF35590.1 - 1e-66 221.5 7.1 4.3e-19 68.9 0.0 6.8 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35590.1 - 6e-48 160.6 2.0 8.2e-11 42.2 0.0 8.8 4 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF35590.1 - 1.8e-47 157.7 0.4 1.5e-05 25.2 0.0 11.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 OWF35590.1 - 4e-46 154.5 6.8 7.8e-10 38.8 0.0 8.8 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF35590.1 - 2.1e-41 135.1 1.7 0.00019 21.6 0.0 11.9 11 0 0 11 11 11 9 Ankyrin repeat NACHT PF05729.12 OWF35590.1 - 0.0099 15.8 0.8 0.46 10.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OWF35590.1 - 0.092 13.1 0.0 36 4.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain DUF4956 PF16316.5 OWF35590.1 - 0.82 9.3 4.0 12 5.5 2.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4956) zf-CSL PF05207.13 OWF35591.1 - 1.3e-25 88.9 2.1 1.7e-25 88.5 2.1 1.2 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 OWF35591.1 - 0.026 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 C4-type zinc ribbon domain Terminase_GpA PF05876.12 OWF35591.1 - 0.16 10.5 0.3 0.17 10.4 0.3 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) RFXA_RFXANK_bdg PF15289.6 OWF35592.1 - 1.6e-12 47.8 0.1 2.2e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Regulatory factor X-associated C-terminal binding domain NHL PF01436.21 OWF35593.1 - 7.9e-27 91.9 9.4 7.4e-08 32.1 0.2 6.3 6 0 0 6 6 6 4 NHL repeat zf-RING_UBOX PF13445.6 OWF35593.1 - 2.2e-09 37.2 3.2 2.2e-09 37.2 3.2 3.2 3 0 0 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 OWF35593.1 - 3.6e-09 36.6 23.6 7.2e-07 29.3 7.7 4.4 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.6 OWF35593.1 - 2.2e-07 30.6 2.7 2.2e-07 30.6 2.7 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF35593.1 - 2.6e-07 30.4 5.9 2.6e-07 30.4 5.9 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF35593.1 - 3.7e-06 27.0 5.3 3.7e-06 27.0 5.3 5.1 4 2 1 5 5 4 1 zinc finger of C3HC4-type, RING DUF5128 PF17170.4 OWF35593.1 - 9.7e-06 24.9 5.9 0.052 12.7 0.3 3.5 3 1 0 3 3 3 2 6-bladed beta-propeller zf-RING_5 PF14634.6 OWF35593.1 - 1.3e-05 25.0 5.5 1.3e-05 25.0 5.5 3.9 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF35593.1 - 0.00025 20.9 5.3 0.00025 20.9 5.3 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF35593.1 - 0.00027 21.2 5.6 0.00027 21.2 5.6 3.7 3 0 0 3 3 3 1 Ring finger domain DUF3583 PF12126.8 OWF35593.1 - 0.00088 18.8 0.2 0.0013 18.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) SGL PF08450.12 OWF35593.1 - 0.0017 18.0 0.4 7.4 6.1 0.1 3.5 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Gp-FAR-1 PF05823.12 OWF35593.1 - 0.011 16.1 3.4 0.22 11.9 0.8 2.3 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SF-assemblin PF06705.11 OWF35593.1 - 0.073 12.4 3.1 0.13 11.6 3.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin KIP1 PF07765.12 OWF35593.1 - 0.32 11.1 1.7 0.69 10.1 1.3 1.8 1 1 0 1 1 1 0 KIP1-like protein Sarcoglycan_1 PF04790.13 OWF35594.1 - 1.9e-31 109.4 0.3 2.1e-31 109.2 0.3 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein vMSA PF00695.19 OWF35594.1 - 0.055 12.6 0.1 0.066 12.3 0.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Peptidase_S7 PF00949.21 OWF35595.1 - 1e-07 31.9 8.0 0.087 12.6 0.1 5.2 1 1 3 4 4 4 3 Peptidase S7, Flavivirus NS3 serine protease FAF PF11250.8 OWF35595.1 - 8.9e-06 25.9 16.4 20 5.5 0.0 9.7 1 1 11 12 12 12 3 Fantastic Four meristem regulator DUF2723 PF11028.8 OWF35596.1 - 0.14 12.0 6.5 0.027 14.4 2.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2723) DUF4079 PF13301.6 OWF35596.1 - 6.7 6.9 13.2 0.45 10.7 2.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) WD40 PF00400.32 OWF35598.1 - 5e-11 43.0 15.9 0.00045 21.0 0.0 6.1 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35598.1 - 6.1e-10 39.3 0.0 0.00019 21.6 0.0 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF35598.1 - 0.0058 15.6 0.1 0.015 14.3 0.1 1.6 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 OWF35598.1 - 0.041 13.1 0.0 0.067 12.4 0.0 1.3 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SET PF00856.28 OWF35599.1 - 5e-13 49.8 0.0 2.9e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 OWF35599.1 - 2.2e-11 44.6 0.8 4.1e-11 43.7 0.8 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding DUF2452 PF10504.9 OWF35600.1 - 4.4e-68 227.7 0.1 5.3e-68 227.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Lectin_C PF00059.21 OWF35601.1 - 1.6e-05 25.6 0.0 4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF35601.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF35601.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF2240 PF09999.9 OWF35602.1 - 0.0067 16.1 0.3 0.33 10.6 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2240) Syntaxin-5_N PF11416.8 OWF35602.1 - 1.8 7.9 14.3 33 3.9 0.1 5.4 2 2 4 6 6 6 0 Syntaxin-5 N-terminal, Sly1p-binding domain ABC_tran PF00005.27 OWF35603.1 - 1.1e-25 90.7 0.0 1.8e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OWF35603.1 - 1.3e-17 64.0 2.6 2.2e-17 63.2 2.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 OWF35603.1 - 4.1e-05 23.5 0.5 0.024 14.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 OWF35603.1 - 0.0031 18.0 0.0 0.0056 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OWF35603.1 - 0.0035 17.0 0.0 0.023 14.3 0.0 2.4 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.19 OWF35603.1 - 0.0035 16.8 0.3 0.93 8.9 0.1 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 OWF35603.1 - 0.0055 16.9 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF35603.1 - 0.011 15.5 1.0 0.14 11.9 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OWF35603.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF35603.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OWF35603.1 - 0.025 14.3 0.1 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF35603.1 - 0.025 14.5 0.2 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 OWF35603.1 - 0.029 14.8 0.2 0.088 13.2 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OWF35603.1 - 0.038 13.9 0.5 0.076 12.9 0.5 1.5 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 OWF35603.1 - 0.056 13.3 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 OWF35603.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Lon_2 PF13337.6 OWF35603.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Dynamin_N PF00350.23 OWF35603.1 - 0.12 12.5 0.3 0.31 11.1 0.3 1.7 1 1 0 1 1 1 0 Dynamin family RNA_helicase PF00910.22 OWF35603.1 - 0.13 12.7 0.1 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 OWF35603.1 - 0.15 11.6 0.3 0.29 10.7 0.3 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OWF35603.1 - 0.19 10.8 0.3 0.32 10.0 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OWF35604.1 - 1.4e-22 80.7 0.0 1.4e-22 80.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 OWF35604.1 - 5.7e-10 39.0 5.6 1.6e-06 27.7 1.2 2.2 1 1 1 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 OWF35604.1 - 0.0038 17.1 0.5 0.025 14.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AIF_C PF14721.6 OWF35604.1 - 0.012 16.0 0.4 0.2 12.0 1.4 2.5 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MAP17 PF15807.5 OWF35604.1 - 0.013 15.7 0.6 0.025 14.8 0.6 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Presenilin PF01080.17 OWF35604.1 - 0.018 13.8 2.9 0.032 13.0 2.9 1.5 1 0 0 1 1 1 0 Presenilin Rota_NSP4 PF01452.16 OWF35604.1 - 0.14 11.9 2.3 0.3 10.8 2.3 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein CCDC71L PF15374.6 OWF35604.1 - 0.37 10.0 8.8 0.56 9.4 8.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Sulfotransfer_1 PF00685.27 OWF35605.1 - 2.4e-09 37.1 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF35605.1 - 1.8e-06 28.5 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family DUF974 PF06159.13 OWF35605.1 - 0.057 13.2 0.4 0.097 12.5 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF974) zf-RING_UBOX PF13445.6 OWF35606.1 - 3.9e-11 42.8 8.8 3.9e-11 42.8 8.8 2.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF35606.1 - 6.7e-09 35.5 7.0 6.7e-09 35.5 7.0 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF35606.1 - 6.7e-09 35.8 5.4 6.7e-09 35.8 5.4 2.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF35606.1 - 6.4e-08 32.8 5.7 6.4e-08 32.8 5.7 2.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF35606.1 - 9.8e-07 28.5 5.9 9.8e-07 28.5 5.9 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF35606.1 - 1.3e-06 28.1 5.0 1.3e-06 28.1 5.0 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF35606.1 - 0.0002 21.2 5.4 0.0002 21.2 5.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 OWF35606.1 - 0.0015 18.3 4.3 0.0039 17.0 4.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 OWF35606.1 - 0.024 14.4 4.0 0.063 13.0 4.0 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 OWF35606.1 - 0.1 12.4 4.7 0.32 10.8 4.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger CNDH2_N PF06278.11 OWF35606.1 - 0.11 12.7 1.6 0.45 10.7 0.3 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Occludin_ELL PF07303.13 OWF35606.1 - 1.3 9.8 5.3 1.2 9.9 3.2 2.0 2 0 0 2 2 1 0 Occludin homology domain DUF1664 PF07889.12 OWF35606.1 - 3.7 7.6 7.2 24 5.0 7.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 OWF35607.1 - 7.8e-85 278.7 9.7 9.2e-20 70.2 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF35607.1 - 6.5e-06 26.2 0.0 3.7 7.7 0.0 5.2 5 0 0 5 5 5 3 RNA recognition motif RRM_occluded PF16842.5 OWF35607.1 - 0.0076 16.1 0.0 11 6.0 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_8 PF11835.8 OWF35607.1 - 0.1 12.8 0.0 11 6.3 0.0 3.2 3 0 0 3 3 3 0 RRM-like domain RRM_2 PF04059.12 OWF35607.1 - 0.13 12.4 0.3 49 4.2 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif 2 BUD22 PF09073.10 OWF35607.1 - 0.17 11.2 77.1 0.036 13.4 52.8 2.9 3 0 0 3 3 3 0 BUD22 PI3K_1B_p101 PF10486.9 OWF35607.1 - 2.4 5.9 38.2 0.0036 15.2 25.7 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SH3_15 PF18346.1 OWF35608.1 - 0.057 13.7 20.0 1.9e+02 2.5 0.0 10.5 12 2 0 12 12 12 0 Mind bomb SH3 repeat domain XRCC1_N PF01834.16 OWF35609.1 - 1.3e-54 184.2 0.1 2.6e-54 183.3 0.1 1.5 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT_2 PF16589.5 OWF35609.1 - 3.1e-21 75.6 0.9 6.2e-12 45.8 0.1 3.2 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OWF35609.1 - 3.8e-20 72.0 0.1 2.7e-09 37.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OWF35609.1 - 7.1e-11 41.9 0.0 7.7e-10 38.6 0.0 2.6 3 0 0 3 3 3 1 twin BRCT domain LIG3_BRCT PF16759.5 OWF35609.1 - 1.5e-09 38.0 1.2 1.8e-06 28.1 0.0 3.0 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OWF35609.1 - 0.088 12.7 0.0 4.8 7.1 0.0 2.8 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DNTTIP1_dimer PF18192.1 OWF35610.1 - 3.9e-27 94.4 0.4 7.5e-27 93.5 0.4 1.5 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain Prp19 PF08606.11 OWF35611.1 - 3e-33 113.6 2.6 7.5e-33 112.3 2.6 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 OWF35611.1 - 3.2e-33 113.2 5.0 3.7e-07 30.7 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35611.1 - 4.5e-14 52.5 0.0 0.032 14.5 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 OWF35611.1 - 7.3e-08 32.5 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 OWF35611.1 - 3.9e-07 29.3 1.7 1.1 8.2 0.0 4.5 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 OWF35611.1 - 1.8e-05 24.5 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit eIF2A PF08662.11 OWF35611.1 - 7.9e-05 22.6 0.3 0.035 14.0 0.1 2.8 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A HPS3_N PF14761.6 OWF35611.1 - 0.00037 20.1 0.0 0.96 8.9 0.0 2.9 1 1 1 3 3 3 2 Hermansky-Pudlak syndrome 3 Nup160 PF11715.8 OWF35611.1 - 0.00057 18.7 0.2 0.063 11.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OWF35611.1 - 0.014 14.2 0.0 0.52 9.0 0.0 2.3 1 1 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 OWF35611.1 - 0.054 12.8 0.0 2.3 7.5 0.1 2.1 1 1 0 2 2 2 0 WD40-like domain T3SSipB PF16535.5 OWF35611.1 - 0.087 13.3 4.2 0.16 12.5 4.2 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB GDPD PF03009.17 OWF35612.1 - 7.5e-27 94.7 0.0 7.5e-26 91.4 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Transglut_core PF01841.19 OWF35613.1 - 0.017 15.6 0.1 0.077 13.4 0.1 2.0 1 1 0 1 1 1 0 Transglutaminase-like superfamily MlaA PF04333.13 OWF35613.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 MlaA lipoprotein LIM PF00412.22 OWF35614.1 - 8.4e-07 29.1 3.7 8.4e-07 29.1 3.7 2.2 2 0 0 2 2 2 1 LIM domain ARGLU PF15346.6 OWF35614.1 - 0.34 10.8 21.0 0.57 10.0 21.0 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Abhydrolase_3 PF07859.13 OWF35615.1 - 6.1e-50 170.0 0.0 1.7e-35 122.8 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OWF35615.1 - 1.9e-11 43.5 0.1 4.6e-11 42.3 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OWF35615.1 - 1.6e-07 30.5 0.5 2.3e-07 30.0 0.5 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase PF07224.11 OWF35615.1 - 0.00025 20.2 0.1 0.00039 19.5 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 OWF35615.1 - 0.00031 19.8 0.0 0.00053 19.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 OWF35615.1 - 0.0027 17.2 0.3 0.012 15.1 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Imm43 PF15570.6 OWF35615.1 - 0.019 15.0 1.5 0.033 14.2 1.5 1.4 1 0 0 1 1 1 0 Immunity protein 43 Thioesterase PF00975.20 OWF35615.1 - 0.043 13.9 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 OWF35615.1 - 0.14 12.0 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OWF35616.1 - 2.7e-39 135.2 0.0 1.2e-24 87.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF35616.1 - 4.3e-06 26.4 0.0 8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OWF35616.1 - 4.1e-05 22.6 0.1 5.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 OWF35616.1 - 0.0089 15.8 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OWF35616.1 - 0.043 13.1 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 OWF35616.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.12 OWF35616.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.28 OWF35616.1 - 0.16 10.8 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF35617.1 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OWF35617.1 - 0.0035 16.3 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family TUDOR PF00567.24 OWF35619.1 - 3.3e-53 178.9 0.1 5.9e-24 84.4 0.0 3.8 3 0 0 3 3 3 3 Tudor domain DEAD PF00270.29 OWF35619.1 - 4.7e-21 75.3 0.0 1.3e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF35619.1 - 0.00049 20.4 0.0 0.0063 16.8 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CS PF04969.16 OWF35619.1 - 0.0015 19.5 0.3 0.0048 17.9 0.3 2.0 1 0 0 1 1 1 1 CS domain MPP6 PF10175.9 OWF35620.1 - 2.9e-30 105.5 4.3 4.7e-30 104.8 4.3 1.3 1 0 0 1 1 1 1 M-phase phosphoprotein 6 GCD14 PF08704.10 OWF35620.1 - 0.13 11.9 0.6 0.18 11.5 0.4 1.3 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF3883 PF13020.6 OWF35622.1 - 9.4e-20 70.5 0.7 2.2e-19 69.3 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) OST-HTH PF12872.7 OWF35622.1 - 3.1e-05 23.7 0.1 0.34 10.8 0.1 3.9 3 0 0 3 3 3 2 OST-HTH/LOTUS domain eIF3_N PF09440.10 OWF35622.1 - 2.4 8.6 5.6 5.4 7.5 2.5 3.3 1 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain DUF3432 PF11914.8 OWF35623.1 - 0.00028 21.1 0.0 0.11 12.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) PT PF04886.12 OWF35623.1 - 0.02 14.4 0.1 34 4.1 0.0 3.8 2 2 3 5 5 5 0 PT repeat Stealth_CR3 PF17102.5 OWF35623.1 - 0.041 13.8 0.4 36 4.3 0.0 4.1 1 1 3 4 4 4 0 Stealth protein CR3, conserved region 3 2H-phosphodiest PF08975.10 OWF35623.1 - 2.7 8.0 6.6 44 4.1 0.9 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1868) zf-B_box PF00643.24 OWF35624.1 - 0.0011 19.1 4.9 0.0021 18.2 4.9 1.5 1 0 0 1 1 1 1 B-box zinc finger LppA PF16708.5 OWF35624.1 - 0.0024 17.8 0.1 0.0038 17.2 0.1 1.2 1 0 0 1 1 1 1 Lipoprotein confined to pathogenic Mycobacterium RE_NgoFVII PF09565.10 OWF35624.1 - 0.043 13.1 1.3 0.054 12.8 0.7 1.5 1 1 0 1 1 1 0 NgoFVII restriction endonuclease RMP PF14996.6 OWF35625.1 - 7.3e-43 146.5 15.1 6.7e-42 143.3 15.1 1.9 1 1 0 1 1 1 1 Retinal Maintenance CD99L2 PF12301.8 OWF35625.1 - 0.014 15.7 0.9 0.017 15.4 0.9 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 Motile_Sperm PF00635.26 OWF35626.1 - 4.2e-32 110.2 0.0 8.4e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 OWF35626.1 - 0.0011 19.1 0.2 0.0028 17.8 0.1 1.7 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GREB1 PF15782.5 OWF35626.1 - 0.085 10.0 3.4 0.1 9.7 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rrp15p PF07890.12 OWF35626.1 - 1.6 9.1 10.9 0.35 11.2 7.7 1.5 2 0 0 2 2 2 0 Rrp15p CUB PF00431.20 OWF35627.1 - 2.4e-38 130.9 1.1 7.4e-22 77.8 0.1 2.9 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 OWF35627.1 - 9.8e-27 92.9 84.5 7.3e-12 45.3 13.0 6.2 6 0 0 6 6 6 5 Low-density lipoprotein receptor domain class A DUF4407 PF14362.6 OWF35627.1 - 0.75 9.1 2.2 1.2 8.4 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSF_DNA-bind PF00447.17 OWF35628.1 - 1.5e-32 112.1 0.4 3.2e-32 111.0 0.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Vert_HS_TF PF06546.11 OWF35628.1 - 1.8e-07 31.1 5.3 4e-07 30.0 5.2 1.6 1 1 0 1 1 1 1 Vertebrate heat shock transcription factor HALZ PF02183.18 OWF35628.1 - 0.0097 16.1 1.5 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper Fez1 PF06818.15 OWF35628.1 - 0.053 14.0 0.5 0.11 12.9 0.5 1.5 1 0 0 1 1 1 0 Fez1 AATF-Che1 PF13339.6 OWF35628.1 - 0.19 12.4 1.1 2.1 9.0 0.1 2.5 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor Lectin_C PF00059.21 OWF35629.1 - 1.7e-06 28.7 0.2 2.6e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain Shisa PF13908.6 OWF35629.1 - 0.09 13.0 0.1 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator CENP-T_C PF15511.6 OWF35630.1 - 9.7e-27 93.2 0.0 2.3e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OWF35630.1 - 1.2e-06 28.8 0.5 4.6e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OWF35630.1 - 0.0011 19.1 0.0 0.0042 17.4 0.0 2.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OWF35630.1 - 0.032 14.6 0.1 0.032 14.6 0.1 4.9 6 1 0 6 6 6 0 Core histone H2A/H2B/H3/H4 RBFA PF02033.18 OWF35631.1 - 1.5e-08 35.0 0.2 5.2e-08 33.3 0.2 1.9 1 0 0 1 1 1 1 Ribosome-binding factor A SID PF11778.8 OWF35631.1 - 0.061 13.4 1.1 0.25 11.5 0.4 2.1 2 0 0 2 2 2 0 Septation initiation Tcf25 PF04910.14 OWF35632.1 - 1.3e-114 382.9 1.3 2e-114 382.3 1.3 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Fis1_TPR_C PF14853.6 OWF35632.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF4710 PF15828.5 OWF35632.1 - 0.49 10.5 17.6 2.8 8.1 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) COPR5 PF15340.6 OWF35632.1 - 3.2 8.4 6.6 6.9 7.3 6.3 1.6 1 1 0 1 1 1 0 Cooperator of PRMT5 family LYRIC PF15686.5 OWF35632.1 - 6.2 6.3 21.6 9.5 5.7 21.6 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF3381 PF11861.8 OWF35632.1 - 6.3 6.6 20.8 13 5.5 20.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FAM60A PF15396.6 OWF35632.1 - 6.6 6.7 9.0 11 6.0 9.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A SRP72 PF08492.12 OWF35632.1 - 10 6.7 17.1 12 6.4 1.2 2.7 2 0 0 2 2 2 0 SRP72 RNA-binding domain RasGAP_C PF03836.15 OWF35633.1 - 0.019 15.1 12.4 0.039 14.1 0.2 2.7 2 1 1 3 3 3 0 RasGAP C-terminus FapA PF03961.13 OWF35633.1 - 0.15 10.7 8.0 0.089 11.4 5.7 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 OWF35633.1 - 0.15 10.0 3.4 0.2 9.6 3.4 1.1 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 OWF35633.1 - 0.17 9.8 3.9 0.22 9.4 1.4 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 OWF35633.1 - 0.22 11.6 4.9 0.46 10.6 4.9 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ribonuc_2-5A PF06479.12 OWF35633.1 - 0.27 11.4 3.5 0.12 12.6 0.9 1.8 2 0 0 2 2 2 0 Ribonuclease 2-5A SlyX PF04102.12 OWF35633.1 - 1.1 9.9 3.9 6.6 7.4 0.2 2.7 2 0 0 2 2 2 0 SlyX Laminin_II PF06009.12 OWF35633.1 - 1.6 8.7 5.9 8.2 6.4 0.7 2.5 1 1 1 2 2 2 0 Laminin Domain II Metallophos PF00149.28 OWF35634.1 - 5.4e-18 66.2 2.6 5.4e-18 66.2 2.6 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OWF35634.1 - 1.5e-16 60.7 0.1 1.5e-16 60.7 0.1 2.2 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OWF35634.1 - 2.9e-16 60.1 0.0 8.5e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C DUF1180 PF06679.12 OWF35634.1 - 0.0021 18.5 0.1 0.0043 17.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) FDF PF09532.10 OWF35634.1 - 0.0029 18.4 0.3 0.0053 17.6 0.3 1.4 1 0 0 1 1 1 1 FDF domain PhoD_N PF16655.5 OWF35634.1 - 0.0057 17.2 0.1 0.02 15.4 0.1 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Orthoreo_P10 PF07204.11 OWF35634.1 - 0.03 14.3 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 OWF35634.1 - 0.083 13.8 0.0 0.72 10.8 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HRG PF16954.5 OWF35634.1 - 0.19 12.1 2.3 11 6.5 0.0 3.1 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene CBP4 PF07960.11 OWF35634.1 - 0.23 11.3 0.7 0.59 10.0 0.7 1.6 1 0 0 1 1 1 0 CBP4 Ank_2 PF12796.7 OWF35635.1 - 3.8e-15 56.2 1.1 4.8e-12 46.3 0.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35635.1 - 9.6e-12 45.2 0.1 1.5e-09 38.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF35635.1 - 8.9e-09 35.4 5.6 7.7e-05 22.9 0.6 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF35635.1 - 9.1e-09 35.4 0.2 0.00023 21.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OWF35635.1 - 7e-08 32.2 0.1 0.038 14.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Death PF00531.22 OWF35635.1 - 0.0014 18.7 0.4 0.0027 17.9 0.4 1.4 1 0 0 1 1 1 1 Death domain DUF3221 PF11518.8 OWF35635.1 - 0.065 13.6 0.2 0.44 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) C1q PF00386.21 OWF35635.1 - 0.18 12.0 0.0 0.53 10.5 0.0 1.8 1 0 0 1 1 1 0 C1q domain Ank_2 PF12796.7 OWF35636.1 - 4.9e-22 78.3 0.6 6e-14 52.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35636.1 - 8e-17 61.4 0.7 4.2e-10 40.0 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF35636.1 - 2.5e-12 46.7 0.4 1.7e-06 28.2 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF35636.1 - 4.4e-12 45.1 0.1 0.0071 16.8 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OWF35636.1 - 1.1e-10 41.4 0.4 0.00094 19.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Death PF00531.22 OWF35636.1 - 0.02 15.1 0.6 0.043 14.0 0.6 1.5 1 0 0 1 1 1 0 Death domain Glycos_transf_2 PF00535.26 OWF35637.1 - 9.1e-37 126.5 0.0 1.5e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF35637.1 - 1.2e-29 103.1 0.9 2e-29 102.4 0.9 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 OWF35637.1 - 2e-07 31.2 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OWF35637.1 - 1.9e-06 27.6 0.0 8.8e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF35637.1 - 5.6e-06 25.9 0.3 1.4e-05 24.7 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 OWF35637.1 - 4.3e-05 24.1 0.1 0.018 15.8 0.1 3.3 3 1 1 4 4 4 1 Ricin-type beta-trefoil lectin domain-like Glyco_trans_2_3 PF13632.6 OWF35637.1 - 0.011 15.6 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 HPIP_like PF18524.1 OWF35637.1 - 0.16 11.7 1.2 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 High potential iron-sulfur protein like Laminin_G_2 PF02210.24 OWF35638.1 - 9.6e-08 32.7 0.3 1.8e-07 31.8 0.3 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 OWF35638.1 - 2.1e-06 28.0 0.0 3.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Per1 PF04080.13 OWF35639.1 - 1.9e-88 296.5 16.1 1.9e-88 296.5 16.1 2.0 2 0 0 2 2 2 1 Per1-like family Nucleos_tra2_N PF01773.20 OWF35639.1 - 0.047 14.3 0.4 0.22 12.2 0.1 2.1 1 1 1 2 2 2 0 Na+ dependent nucleoside transporter N-terminus TPH PF13868.6 OWF35640.1 - 1.8e-15 56.4 103.6 1.8e-15 56.4 103.6 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain CheX PF13690.6 OWF35640.1 - 0.17 12.1 0.7 1.4 9.1 0.1 2.8 3 0 0 3 3 3 0 Chemotaxis phosphatase CheX Put_Phosphatase PF06888.12 OWF35641.1 - 1.4e-73 247.2 0.0 1.7e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 OWF35641.1 - 2.2e-11 44.5 0.0 5.7e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OWF35641.1 - 1.8e-05 24.9 0.9 0.0019 18.3 0.8 3.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OWF35641.1 - 0.0049 17.2 0.0 0.043 14.1 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 OWF35641.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Connexin40_C PF16791.5 OWF35641.1 - 0.13 13.6 0.1 0.42 11.9 0.1 1.9 1 1 0 1 1 1 0 Connexin 40 C-terminal domain RicinB_lectin_2 PF14200.6 OWF35642.1 - 0.041 14.6 0.4 0.26 12.0 0.6 1.9 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like OAF PF14941.6 OWF35643.1 - 2e-94 315.6 1.0 2.3e-94 315.4 1.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first BRICHOS PF04089.14 OWF35643.1 - 0.054 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 BRICHOS domain FlgD_ig PF13860.6 OWF35643.1 - 0.27 11.1 1.2 0.68 9.8 1.2 1.6 1 1 1 2 2 2 0 FlgD Ig-like domain DUF1682 PF07946.14 OWF35644.1 - 1.2e-90 304.1 10.6 1.4e-90 303.8 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Neur_chan_LBD PF02931.23 OWF35647.1 - 1.5e-64 217.4 5.3 2.7e-64 216.6 5.3 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF35647.1 - 7.7e-38 130.9 4.3 6.8e-37 127.8 4.3 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 OWF35647.1 - 2.1 7.7 7.1 1.5 8.1 2.6 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) MG2 PF01835.19 OWF35648.1 - 5e-06 26.9 10.4 0.33 11.4 0.4 5.2 1 1 4 5 5 5 3 MG2 domain UPF0300 PF08594.10 OWF35648.1 - 0.062 12.6 2.1 11 5.3 0.0 3.8 1 1 4 5 5 5 0 Uncharacterised protein family (UPF0300) LysR_substrate PF03466.20 OWF35648.1 - 0.22 10.9 0.5 3.8 6.8 0.0 2.6 1 1 1 2 2 2 0 LysR substrate binding domain Hum_adeno_E3A PF05393.11 OWF35648.1 - 0.71 9.9 7.5 73 3.4 0.3 4.5 1 1 4 5 5 5 0 Human adenovirus early E3A glycoprotein DR2241 PF18069.1 OWF35648.1 - 3.4 7.6 10.6 3.8 7.4 0.4 3.6 1 1 4 5 5 5 0 DR2241 stabilising domain PHD PF00628.29 OWF35649.1 - 0.00071 19.4 5.7 0.0015 18.4 5.7 1.5 1 0 0 1 1 1 1 PHD-finger Exo_endo_phos PF03372.23 OWF35649.1 - 0.074 12.6 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family C1_1 PF00130.22 OWF35649.1 - 0.3 11.0 3.1 0.79 9.7 3.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CNRIP1 PF15043.6 OWF35650.1 - 5.4e-44 149.5 0.9 6e-44 149.4 0.9 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 Peptidase_M4 PF01447.18 OWF35651.1 - 3.1e-26 92.6 0.0 6e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.15 OWF35651.1 - 2.1e-22 79.7 0.0 4.6e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain FTP PF07504.13 OWF35651.1 - 1.4e-07 31.3 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF2018 PF09442.10 OWF35651.1 - 0.18 12.8 0.0 0.46 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) PLAT PF01477.23 OWF35652.1 - 5.5e-49 165.6 13.0 3.3e-20 72.8 0.2 4.4 4 0 0 4 4 4 3 PLAT/LH2 domain ATS3 PF06232.11 OWF35652.1 - 6e-08 32.7 0.0 0.012 15.5 0.0 3.3 3 0 0 3 3 3 3 Embryo-specific protein 3, (ATS3) SRP-alpha_N PF04086.13 OWF35652.1 - 0.13 12.2 20.9 0.23 11.4 20.9 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TMF_TATA_bd PF12325.8 OWF35653.1 - 0.0065 16.7 12.3 0.13 12.5 4.9 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF4259 PF14078.6 OWF35653.1 - 0.0068 17.1 0.2 0.013 16.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4259) DUF1811 PF08838.10 OWF35653.1 - 0.0078 16.4 2.5 0.85 9.9 0.6 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1811) Jnk-SapK_ap_N PF09744.9 OWF35653.1 - 0.0085 16.3 6.0 0.0085 16.3 6.0 2.2 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 Fez1 PF06818.15 OWF35653.1 - 0.016 15.7 6.0 0.023 15.1 6.0 1.3 1 0 0 1 1 1 0 Fez1 ABC_tran_CTD PF16326.5 OWF35653.1 - 0.017 15.4 4.2 0.017 15.4 4.2 1.9 2 1 0 2 2 1 0 ABC transporter C-terminal domain SKA2 PF16740.5 OWF35653.1 - 0.022 14.5 6.2 0.035 13.9 4.5 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 OWF35653.1 - 0.023 14.5 9.3 0.51 10.2 0.6 3.3 2 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.11 OWF35653.1 - 0.023 13.6 10.8 0.2 10.5 2.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin_3 PF13758.6 OWF35653.1 - 0.061 13.4 4.4 0.98 9.5 0.2 3.3 2 1 1 3 3 3 0 Prefoldin subunit ZapB PF06005.12 OWF35653.1 - 0.1 13.0 13.8 0.41 11.1 2.3 3.3 1 1 1 2 2 2 0 Cell division protein ZapB HMMR_C PF15908.5 OWF35653.1 - 0.22 11.8 8.2 0.83 9.9 3.7 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal YabA PF06156.13 OWF35653.1 - 0.37 11.5 13.2 15 6.3 10.5 3.2 1 1 2 3 3 3 0 Initiation control protein YabA BRE1 PF08647.11 OWF35653.1 - 1.2 9.3 9.9 2.9 8.0 1.2 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 OWF35653.1 - 1.3 8.8 10.0 0.8 9.5 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 OWF35653.1 - 1.6 8.8 9.9 8.8 6.4 8.7 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Bap31_Bap29_C PF18035.1 OWF35653.1 - 2.3 8.3 7.1 12 6.0 7.1 2.4 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain CENP-F_leu_zip PF10473.9 OWF35653.1 - 3.1 7.8 14.5 28 4.7 14.5 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 OWF35653.1 - 3.5 7.9 12.1 9.6 6.5 0.2 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Uso1_p115_C PF04871.13 OWF35653.1 - 3.8 7.9 9.5 1.8 8.9 2.7 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 OWF35653.1 - 3.8 7.7 10.2 35 4.5 10.3 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OWF35653.1 - 3.9 7.5 6.0 7.2 6.7 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 OWF35653.1 - 6.3 6.9 11.2 22 5.1 10.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc24 PF08286.11 OWF35653.1 - 7.2 6.9 12.2 36 4.7 5.1 3.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 OWF35653.1 - 7.8 4.3 8.0 13 3.6 7.6 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CEP209_CC5 PF16574.5 OWF35653.1 - 7.8 6.7 12.0 1.4 9.1 2.5 2.7 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 WD40 PF00400.32 OWF35654.1 - 4.7e-36 122.2 26.1 1.2e-06 29.1 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box PF00646.33 OWF35654.1 - 1.7e-08 34.1 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 OWF35654.1 - 1.7e-07 31.4 7.9 0.37 11.1 0.1 5.8 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 OWF35654.1 - 4.3e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 OWF35654.1 - 1.6e-05 24.4 4.1 0.00031 20.2 0.8 2.6 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 OWF35654.1 - 0.01 14.5 4.3 1 7.9 0.1 3.6 2 2 1 4 4 4 0 Nucleoporin Nup120/160 Hira PF07569.11 OWF35654.1 - 0.22 11.2 2.4 47 3.6 0.1 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split Fis1_TPR_N PF14852.6 OWF35655.1 - 3.3e-09 36.3 0.0 64 3.4 0.0 11.6 14 1 1 15 15 15 0 Fis1 N-terminal tetratricopeptide repeat DUF1641 PF07849.11 OWF35655.1 - 0.00053 19.8 35.6 58 3.7 0.0 17.8 24 0 0 24 24 24 0 Protein of unknown function (DUF1641) TIG_plexin PF17960.1 OWF35655.1 - 0.0094 15.9 38.5 3.9 7.5 3.1 10.2 1 1 6 7 7 7 3 TIG domain Gp138_N PF18352.1 OWF35655.1 - 0.013 15.5 8.5 6.7 6.9 0.0 5.5 2 2 2 5 5 5 0 Phage protein Gp138 N-terminal domain LRRCT PF01463.24 OWF35655.1 - 0.28 11.8 19.0 87 4.0 0.0 9.7 7 4 5 12 12 12 0 Leucine rich repeat C-terminal domain UDPG_MGDP_dh PF00984.19 OWF35655.1 - 0.4 10.9 1.9 1e+02 3.2 0.1 3.9 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain 17kDa_Anti_2 PF16998.5 OWF35655.1 - 5.5 6.9 21.4 1.2 9.1 0.3 5.2 3 2 1 4 4 4 0 17 kDa outer membrane surface antigen PIP49_C PF12260.8 OWF35656.1 - 3.2e-06 26.9 0.0 7.3e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 OWF35656.1 - 1.4e-05 24.5 0.1 2.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF35656.1 - 0.00063 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 OWF35659.1 - 3.6e-23 81.7 28.6 8.6e-14 51.6 10.8 3.5 3 1 0 3 3 3 2 Kringle domain SNF PF00209.18 OWF35660.1 - 3.4e-09 35.9 0.3 4e-09 35.7 0.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family HbrB PF08539.11 OWF35661.1 - 0.089 12.8 0.4 0.18 11.8 0.4 1.5 1 0 0 1 1 1 0 HbrB-like Keratin_2_head PF16208.5 OWF35664.1 - 0.039 14.1 18.0 0.045 13.9 18.0 1.1 1 0 0 1 1 1 0 Keratin type II head DUF3318 PF11780.8 OWF35664.1 - 0.25 11.3 0.5 0.33 10.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Synaptobrevin PF00957.21 OWF35665.1 - 6.5e-14 51.5 0.3 1e-13 50.9 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OWF35665.1 - 6.7e-08 32.5 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SecM PF06558.12 OWF35665.1 - 0.22 11.6 0.3 0.32 11.1 0.3 1.2 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) RRN3 PF05327.11 OWF35666.1 - 0.015 13.8 1.5 0.02 13.5 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.12 OWF35666.1 - 0.14 11.9 11.3 0.21 11.3 11.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 OWF35666.1 - 0.23 11.3 5.3 0.37 10.6 5.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SAM_2 PF07647.17 OWF35667.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH2 PF00017.24 OWF35667.1 - 6.9e-07 29.3 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SAM_1 PF00536.30 OWF35667.1 - 6.8e-05 23.2 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) S1 PF00575.23 OWF35668.1 - 9.5e-66 218.1 12.4 1.9e-08 34.5 0.0 14.1 14 0 0 14 14 14 13 S1 RNA binding domain Suf PF05843.14 OWF35668.1 - 3.3e-13 50.3 10.9 5.6e-13 49.5 2.5 4.9 2 1 1 4 4 3 2 Suppressor of forked protein (Suf) PPR PF01535.20 OWF35668.1 - 1.2e-10 40.8 0.2 0.00017 21.6 0.0 3.9 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.6 OWF35668.1 - 1.3e-10 41.6 0.0 0.0067 16.9 0.0 4.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF35668.1 - 9.1e-08 32.3 0.2 1.2 10.2 0.7 5.7 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF35668.1 - 2.7e-06 27.9 0.0 0.087 13.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 OWF35668.1 - 6.4e-06 25.6 4.0 0.33 10.1 0.1 3.0 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OWF35668.1 - 0.00014 21.6 1.0 0.95 9.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF35668.1 - 0.00019 21.6 0.6 0.2 12.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF35668.1 - 0.0003 21.2 3.1 7.4 7.4 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR_2 PF13041.6 OWF35668.1 - 0.00052 20.2 0.2 0.064 13.5 0.0 3.4 3 0 0 3 3 3 1 PPR repeat family TPR_2 PF07719.17 OWF35668.1 - 0.0039 17.2 2.1 0.74 10.1 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2110 PF09883.9 OWF35668.1 - 0.0045 16.6 0.1 0.19 11.3 0.0 2.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2110) PPR_1 PF12854.7 OWF35668.1 - 0.0069 16.1 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 1 PPR repeat Clathrin PF00637.20 OWF35668.1 - 0.0079 16.1 1.8 0.0079 16.1 1.8 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.28 OWF35668.1 - 0.018 14.8 1.4 5.9 6.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RAMPs PF03787.15 OWF35668.1 - 0.023 14.7 0.6 0.068 13.2 0.6 1.8 1 0 0 1 1 1 0 RAMP superfamily Acyl-CoA_dh_1 PF00441.24 OWF35669.1 - 1.8e-48 164.6 0.4 5.1e-48 163.1 0.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OWF35669.1 - 2.3e-27 95.9 0.0 4.8e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OWF35669.1 - 5.3e-25 87.4 0.0 9.8e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF35669.1 - 9.1e-25 87.5 0.0 1.1e-23 84.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4500 PF14937.6 OWF35670.1 - 1.4e-25 89.1 0.1 1.8e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) Ank_2 PF12796.7 OWF35671.1 - 1.1e-20 74.0 3.0 2.7e-06 27.9 0.1 5.0 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF35671.1 - 9.2e-17 61.2 1.2 0.0022 18.5 0.0 6.7 4 3 4 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF35671.1 - 4e-15 55.7 0.9 0.00026 21.2 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF35671.1 - 3.7e-13 48.4 1.2 0.00049 20.3 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 OWF35671.1 - 4.4e-10 39.6 3.4 0.002 18.5 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat zf-B_box PF00643.24 OWF35672.1 - 1.1e-11 44.7 22.6 6e-06 26.3 4.2 2.5 2 0 0 2 2 2 2 B-box zinc finger ATP-cone PF03477.16 OWF35672.1 - 0.029 14.9 2.4 0.42 11.2 2.3 2.3 1 1 0 1 1 1 0 ATP cone domain Exonuc_VII_L PF02601.15 OWF35672.1 - 0.11 12.1 3.3 0.16 11.5 3.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mt_ATP-synt_D PF05873.12 OWF35672.1 - 0.24 11.3 10.6 0.16 11.8 4.3 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) PhnG PF06754.12 OWF35672.1 - 0.5 10.3 3.8 10 6.1 0.0 3.0 2 1 1 3 3 3 0 Phosphonate metabolism protein PhnG DUF4407 PF14362.6 OWF35672.1 - 0.82 9.0 5.2 1.2 8.5 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_topoisoIV PF00521.20 OWF35672.1 - 1 8.2 8.4 1.4 7.8 8.4 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF1664 PF07889.12 OWF35672.1 - 1.5 8.9 5.7 2.9 7.9 5.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2524 PF10732.9 OWF35672.1 - 6 7.2 10.1 0.38 11.1 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Ank_4 PF13637.6 OWF35673.1 - 4.5e-12 46.2 0.1 7.9e-05 23.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF35673.1 - 2.5e-08 34.4 0.2 2.4e-05 24.8 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF35673.1 - 2.7e-08 33.9 0.2 0.0044 17.3 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF35673.1 - 8.7e-08 32.3 1.5 0.12 12.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OWF35673.1 - 2.6e-07 30.4 0.3 1.6 9.5 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeat RNA_replicase_B PF03431.13 OWF35673.1 - 0.048 12.1 0.0 0.057 11.9 0.0 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain Acyl_transf_3 PF01757.22 OWF35674.1 - 4.3e-26 91.8 44.4 6.7e-26 91.2 44.4 1.3 1 0 0 1 1 1 1 Acyltransferase family BRICHOS PF04089.14 OWF35675.1 - 0.071 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 BRICHOS domain BRICHOS PF04089.14 OWF35676.1 - 0.026 14.8 0.0 0.047 13.9 0.0 1.4 1 1 0 1 1 1 0 BRICHOS domain BRICHOS PF04089.14 OWF35678.1 - 0.0064 16.7 0.1 0.0098 16.1 0.1 1.3 1 0 0 1 1 1 1 BRICHOS domain BRICHOS PF04089.14 OWF35679.1 - 0.00018 21.6 0.1 0.00027 21.1 0.1 1.3 1 0 0 1 1 1 1 BRICHOS domain Acyl-ACP_TE PF01643.17 OWF35680.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Elongin_A PF06881.11 OWF35680.1 - 0.0034 17.9 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A 4HBT_2 PF13279.6 OWF35680.1 - 0.022 15.2 0.3 0.44 11.0 0.2 2.2 2 0 0 2 2 2 0 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF35681.1 - 1e-06 28.2 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Elongin_A PF06881.11 OWF35681.1 - 0.0035 17.8 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A 4HBT_2 PF13279.6 OWF35681.1 - 0.012 16.1 0.2 0.79 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF35682.1 - 2.5e-08 33.5 0.0 3.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase Acyl-ACP_TE PF01643.17 OWF35683.1 - 6.7e-09 35.4 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF35683.1 - 0.022 15.2 0.2 4 8.0 0.1 2.3 2 0 0 2 2 2 0 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF35684.1 - 1.4e-06 27.8 0.0 3.1e-06 26.7 0.0 1.6 1 1 1 2 2 2 1 Acyl-ACP thioesterase WSC PF01822.19 OWF35685.1 - 2.4e-18 66.1 12.6 2.4e-18 66.1 12.6 2.3 2 0 0 2 2 2 1 WSC domain Lipase_GDSL_2 PF13472.6 OWF35686.1 - 1.5e-08 35.2 0.0 1.8e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF35686.1 - 0.094 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase NAC PF01849.18 OWF35687.1 - 1.2e-24 86.0 1.3 5.1e-24 84.0 0.3 2.1 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 OWF35687.1 - 0.15 11.9 0.8 0.5 10.2 0.1 2.2 3 0 0 3 3 3 0 UBA-like domain Annexin PF00191.20 OWF35688.1 - 1.2e-182 592.3 24.8 7.1e-27 93.3 0.8 8.5 8 0 0 8 8 8 8 Annexin CHB_HEX_C_1 PF13290.6 OWF35688.1 - 4.3e-08 33.1 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 OWF35688.1 - 1.2e-07 31.7 0.0 3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Fn3 associated Myb_DNA-bind_7 PF15963.5 OWF35688.1 - 0.012 15.5 9.0 38 4.3 0.0 6.1 5 1 1 6 6 6 0 Myb DNA-binding like DUF905 PF06006.12 OWF35688.1 - 0.18 11.8 0.0 0.51 10.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) zf-RING_2 PF13639.6 OWF35689.1 - 7.3e-11 42.2 9.0 7.3e-11 42.2 9.0 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 OWF35689.1 - 1.1e-06 28.8 9.1 3.5e-06 27.2 9.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OWF35689.1 - 1.8e-06 27.6 7.3 1.8e-06 27.6 7.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF35689.1 - 5.9e-06 26.2 1.7 5.9e-06 26.2 1.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF35689.1 - 1.7e-05 24.8 5.2 8.6e-05 22.5 5.2 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OWF35689.1 - 2.3e-05 24.1 8.4 2.3e-05 24.1 8.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF35689.1 - 3.8e-05 23.3 6.8 3.8e-05 23.3 6.8 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 OWF35689.1 - 3.8e-05 23.6 7.5 0.00014 21.7 7.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF35689.1 - 6.8e-05 22.6 5.4 6.8e-05 22.6 5.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF35689.1 - 0.00068 19.5 7.2 0.0016 18.3 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OWF35689.1 - 0.0015 18.1 6.5 0.0052 16.4 6.5 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OWF35689.1 - 0.0022 18.1 8.8 0.0043 17.1 8.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.8 OWF35689.1 - 0.013 15.3 4.5 0.03 14.2 4.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.11 OWF35689.1 - 0.015 15.2 0.4 0.028 14.3 0.4 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING-like PF08746.11 OWF35689.1 - 0.061 13.7 5.4 0.19 12.0 5.4 1.9 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 OWF35689.1 - 0.4 10.9 5.6 1.9 8.7 5.7 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OWF35689.1 - 0.89 9.8 10.6 2 8.6 7.6 2.8 2 1 1 3 3 3 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 OWF35689.1 - 0.98 9.5 10.4 1.6 8.9 7.4 2.7 2 1 0 2 2 2 0 Zinc-finger RecR PF02132.15 OWF35689.1 - 2.9 7.6 6.3 17 5.1 0.1 2.9 3 0 0 3 3 3 0 RecR protein zf-B_box PF00643.24 OWF35690.1 - 6.7e-14 51.8 17.8 2e-07 31.0 4.9 2.6 2 0 0 2 2 2 2 B-box zinc finger AAA_13 PF13166.6 OWF35690.1 - 0.0026 16.5 2.9 0.0035 16.0 2.9 1.1 1 0 0 1 1 1 1 AAA domain Clathrin PF00637.20 OWF35690.1 - 0.048 13.5 0.3 0.5 10.2 0.2 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS TcpQ PF10671.9 OWF35690.1 - 0.16 12.1 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q zf-H2C2_2 PF13465.6 OWF35690.1 - 0.45 11.0 3.1 26 5.4 0.1 3.2 2 0 0 2 2 2 0 Zinc-finger double domain FA_hydroxylase PF04116.13 OWF35691.1 - 8.4e-27 94.1 10.3 8.4e-27 94.1 10.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Laminin_G_2 PF02210.24 OWF35692.1 - 1.5e-73 245.3 14.5 4.4e-25 88.7 0.2 4.3 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 OWF35692.1 - 1.4e-55 187.1 7.6 1.9e-23 83.1 0.1 4.6 4 0 0 4 4 4 4 Laminin G domain F5_F8_type_C PF00754.25 OWF35692.1 - 7.5e-23 81.0 1.4 2.3e-21 76.2 0.1 3.1 3 0 0 3 3 3 1 F5/8 type C domain EGF PF00008.27 OWF35692.1 - 1.5e-10 41.2 39.1 1.5e-06 28.4 9.8 3.7 3 0 0 3 3 3 2 EGF-like domain PTP_tm PF18861.1 OWF35692.1 - 0.00085 19.4 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J hEGF PF12661.7 OWF35692.1 - 0.0025 18.4 7.5 0.0025 18.4 7.5 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF Lectin_C PF00059.21 OWF35693.1 - 0.0016 19.2 0.2 0.0018 19.0 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain tRNA-synt_2 PF00152.20 OWF35694.1 - 9.6e-80 268.0 0.2 1.6e-79 267.3 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OWF35694.1 - 6.5e-06 26.0 2.1 1.4e-05 25.0 2.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OWF35694.1 - 9e-05 22.1 2.0 0.42 10.1 0.9 2.8 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-H2C2_2 PF13465.6 OWF35695.1 - 1.3e-22 79.2 84.1 6.5e-08 32.7 1.1 13.1 14 0 0 14 14 14 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF35695.1 - 1.8e-22 78.0 101.7 0.0036 18.0 0.8 12.6 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF35695.1 - 1.6e-21 75.5 106.1 0.0085 16.5 0.2 12.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF35695.1 - 2.1e-05 24.7 71.4 0.05 13.9 0.3 12.4 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OWF35695.1 - 0.00017 21.3 5.6 0.00062 19.5 2.2 9.4 11 1 0 11 11 11 4 C2H2-type zinc-finger domain BolA PF01722.18 OWF35695.1 - 0.0023 18.2 0.8 0.16 12.2 0.2 4.0 4 0 0 4 4 4 1 BolA-like protein zf-C2H2_6 PF13912.6 OWF35695.1 - 0.0032 17.4 63.8 0.14 12.2 0.6 10.2 10 0 0 10 10 10 5 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 OWF35695.1 - 0.14 12.4 12.1 1.6 9.1 0.0 5.1 4 1 0 4 4 4 0 zinc-ribbon zf-C2H2_2 PF12756.7 OWF35695.1 - 9.7 6.6 73.1 0.73 10.2 11.1 11.7 5 5 6 11 11 11 0 C2H2 type zinc-finger (2 copies) PHD PF00628.29 OWF35696.1 - 2.8e-30 104.0 57.1 5.2e-10 39.1 10.6 5.1 5 0 0 5 5 5 4 PHD-finger zf-HC5HC2H_2 PF13832.6 OWF35696.1 - 7.2e-26 90.5 1.4 7.2e-26 90.5 1.4 4.5 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OWF35696.1 - 7.5e-18 64.6 37.9 4e-17 62.2 1.3 4.8 4 0 0 4 4 4 3 PHD-like zinc-binding domain PHD_2 PF13831.6 OWF35696.1 - 9.4e-07 28.3 42.9 2.5e-06 26.9 7.7 6.2 5 2 0 5 5 5 2 PHD-finger Prok-RING_1 PF14446.6 OWF35696.1 - 4e-06 26.7 38.7 9.7e-05 22.2 3.6 5.0 4 0 0 4 4 4 3 Prokaryotic RING finger family 1 C1_1 PF00130.22 OWF35696.1 - 0.00078 19.3 1.9 0.00078 19.3 1.9 6.9 5 2 2 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) HALZ PF02183.18 OWF35696.1 - 0.001 19.3 0.5 0.001 19.3 0.5 2.0 2 0 0 2 2 1 1 Homeobox associated leucine zipper Laminin_I PF06008.14 OWF35696.1 - 0.016 14.9 3.1 0.03 14.0 3.1 1.5 1 0 0 1 1 1 0 Laminin Domain I JIP_LZII PF16471.5 OWF35696.1 - 0.17 12.1 5.3 0.1 12.8 1.8 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4746 PF15928.5 OWF35696.1 - 0.19 11.1 0.1 0.19 11.1 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4746) Sporozoite_P67 PF05642.11 OWF35696.1 - 1 7.3 9.7 2.4 6.1 9.7 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Claudin_2 PF13903.6 OWF35697.1 - 3.4e-09 36.7 10.4 5.4e-09 36.1 10.4 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF35697.1 - 1.1e-08 35.2 6.8 1.7e-08 34.5 6.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 OWF35697.1 - 1.8e-05 24.7 4.4 2.8e-05 24.1 4.4 1.3 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DuoxA PF10204.9 OWF35697.1 - 0.0014 17.7 6.7 0.0014 17.7 6.7 1.6 2 0 0 2 2 2 1 Dual oxidase maturation factor Amastin PF07344.11 OWF35697.1 - 0.4 10.5 14.5 0.57 10.0 11.7 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF1772 PF08592.11 OWF35697.1 - 1.1 9.6 4.9 3.1 8.1 5.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF998 PF06197.13 OWF35697.1 - 1.2 8.7 11.2 0.43 10.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF998) DUF2070 PF09843.9 OWF35697.1 - 2.1 6.5 7.1 3.3 5.9 7.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WBP-1 PF11669.8 OWF35699.1 - 5.5e-06 27.0 0.0 1.3e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 WW domain-binding protein 1 RCR PF12273.8 OWF35699.1 - 0.15 12.7 1.7 0.36 11.5 1.7 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MLANA PF14991.6 OWF35699.1 - 0.38 11.0 4.4 0.097 13.0 0.4 2.0 2 1 0 2 2 2 0 Protein melan-A Rick_17kDa_Anti PF05433.15 OWF35699.1 - 1 9.2 6.2 1.9 8.4 0.7 2.4 3 0 0 3 3 3 0 Glycine zipper 2TM domain Peptidase_G2 PF11962.8 OWF35700.1 - 0.094 12.1 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase_G2, IMC autoproteolytic cleavage domain DUF393 PF04134.12 OWF35702.1 - 0.005 18.2 0.1 0.0076 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF393 UBX PF00789.20 OWF35703.1 - 1.8e-14 53.7 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 OWF35703.1 - 1.9e-13 50.4 0.0 3.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OWF35703.1 - 0.004 17.6 0.1 0.0097 16.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain PRCC PF10253.9 OWF35703.1 - 2.4 8.9 15.2 0.64 10.8 12.2 1.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting EGF PF00008.27 OWF35704.1 - 1.4e-40 137.2 171.8 6.8e-06 26.3 6.3 13.2 12 1 0 12 12 12 12 EGF-like domain 7tm_2 PF00002.24 OWF35704.1 - 3.5e-20 72.4 9.9 5.7e-20 71.6 9.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cadherin PF00028.17 OWF35704.1 - 5.4e-14 52.4 1.2 5.1e-11 42.9 0.2 3.5 4 0 0 4 4 4 2 Cadherin domain hEGF PF12661.7 OWF35704.1 - 2.1e-10 40.8 145.3 0.0013 19.3 6.0 14.7 12 1 0 12 12 12 7 Human growth factor-like EGF GAIN PF16489.5 OWF35704.1 - 2.9e-10 39.9 4.5 4.5e-10 39.3 4.5 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain EGF_2 PF07974.13 OWF35704.1 - 1.9e-06 28.1 194.4 0.31 11.5 8.4 12.8 12 0 0 12 12 12 10 EGF-like domain fn3 PF00041.21 OWF35704.1 - 0.00029 21.1 0.8 0.0023 18.2 0.1 2.8 3 0 0 3 3 3 1 Fibronectin type III domain Gal-3-0_sulfotr PF06990.11 OWF35705.1 - 2.6e-44 151.7 2.5 3.2e-44 151.4 2.5 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Ion_trans PF00520.31 OWF35706.1 - 7.9e-43 146.4 7.3 1e-42 146.0 7.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF35706.1 - 2.9e-22 78.8 0.1 4.8e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF35706.1 - 4.6e-13 48.9 0.4 4.6e-13 48.9 0.4 2.3 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 OWF35707.1 - 4.8e-41 140.6 8.0 6.5e-41 140.2 8.0 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF35707.1 - 3.4e-27 94.6 0.0 6.7e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF35707.1 - 1.5e-11 44.1 3.4 1.5e-11 44.1 3.4 2.2 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 OWF35707.1 - 0.028 13.1 4.0 0.07 11.8 0.3 2.3 1 1 1 2 2 2 0 Polycystin cation channel HlyIII PF03006.20 OWF35708.1 - 0.051 13.3 1.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Haemolysin-III related Baculo_PEP_C PF04513.12 OWF35710.1 - 3.8e-08 33.5 29.0 0.025 14.6 1.7 5.2 1 1 4 5 5 5 5 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OWF35710.1 - 0.014 15.2 0.0 30 4.4 0.0 3.8 2 2 2 4 4 4 0 Apolipoprotein A1/A4/E domain 7tm_1 PF00001.21 OWF35711.1 - 5.6e-29 101.3 6.0 7.7e-29 100.8 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COX7C PF02935.16 OWF35711.1 - 1.6 9.1 7.1 0.43 10.9 1.7 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc 7tm_1 PF00001.21 OWF35712.1 - 4.1e-31 108.3 10.0 5.3e-31 107.9 10.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NHL PF01436.21 OWF35714.1 - 3.4e-15 55.2 7.6 5.2e-06 26.2 0.2 6.1 6 1 0 6 6 6 3 NHL repeat DUF5128 PF17170.4 OWF35714.1 - 1.1e-07 31.4 3.4 2.9e-05 23.4 1.4 3.5 2 1 1 3 3 3 2 6-bladed beta-propeller SGL PF08450.12 OWF35714.1 - 0.0004 20.0 0.2 0.016 14.8 0.2 3.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region HepII_C PF18675.1 OWF35714.1 - 0.042 13.9 1.0 0.36 11.0 0.0 2.8 3 0 0 3 3 3 0 Heparinase II C-terminal domain DUF4934 PF16288.5 OWF35714.1 - 0.052 13.5 1.7 1.3 9.0 0.0 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4934) Neuroparsin PF07327.11 OWF35714.1 - 0.084 13.3 0.0 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Neuroparsin SdiA-regulated PF06977.11 OWF35714.1 - 0.12 11.6 0.0 0.71 9.0 0.0 2.2 1 1 1 2 2 2 0 SdiA-regulated Hormone_6 PF00236.18 OWF35715.1 - 2.1e-06 27.6 4.7 7.8 6.6 0.0 6.1 1 1 4 5 5 5 5 Glycoprotein hormone Hormone_6 PF00236.18 OWF35716.1 - 3.7e-09 36.4 0.8 8.4 6.5 0.0 6.9 1 1 7 8 8 8 7 Glycoprotein hormone Kunitz_BPTI PF00014.23 OWF35717.1 - 4.6e-13 49.2 14.8 1.3e-08 35.0 5.5 2.8 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Antistasin PF02822.14 OWF35717.1 - 2.9e-05 24.6 3.1 2.9e-05 24.6 3.1 3.5 5 0 0 5 5 5 1 Antistasin family Toxin_28 PF08115.11 OWF35717.1 - 0.41 10.6 14.4 4 7.4 2.9 4.1 4 0 0 4 4 4 0 SFI toxin family Plasmodium_HRP PF05403.11 OWF35719.1 - 9.6e-11 41.9 8.7 0.0032 17.3 4.9 3.8 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) Lipin_mid PF16876.5 OWF35719.1 - 0.076 13.2 27.8 24 5.1 0.1 9.6 1 1 11 12 12 12 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Baculo_PEP_C PF04513.12 OWF35720.1 - 0.01 15.9 0.0 5.7 7.0 0.0 3.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus BCS1_N PF08740.11 OWF35721.1 - 1.1e-41 142.8 1.2 1.6e-41 142.4 1.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OWF35721.1 - 2.5e-20 73.2 0.0 4.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OWF35721.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OWF35721.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OWF35721.1 - 0.006 16.6 0.0 0.016 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OWF35721.1 - 0.0083 16.5 0.0 0.019 15.3 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 OWF35721.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OWF35721.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 OWF35721.1 - 0.021 14.7 0.0 0.07 13.0 0.0 1.8 1 1 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 OWF35721.1 - 0.028 14.6 0.0 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OWF35721.1 - 0.046 14.2 0.0 0.08 13.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OWF35721.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 OWF35721.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OWF35721.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 OWF35722.1 - 4.1e-16 59.1 0.0 6.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35722.1 - 8.6e-09 35.0 0.0 2.2e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF35722.1 - 0.0002 20.3 0.5 0.00034 19.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OWF35722.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Actin PF00022.19 OWF35723.1 - 8.6e-44 149.7 0.0 2.6e-42 144.9 0.0 2.3 1 1 0 1 1 1 1 Actin LRR_6 PF13516.6 OWF35723.1 - 1.1e-07 31.3 14.7 0.088 12.9 0.0 6.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 OWF35723.1 - 0.022 14.5 7.1 16 5.3 0.1 4.5 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 OWF35723.1 - 0.091 13.2 11.2 2.8 8.5 1.5 4.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Helicase_C PF00271.31 OWF35726.1 - 2.3e-16 60.1 0.1 8.9e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TUDOR PF00567.24 OWF35726.1 - 5.1e-16 58.8 0.3 3.1e-15 56.3 0.0 2.4 3 0 0 3 3 3 1 Tudor domain HA2 PF04408.23 OWF35726.1 - 1.5e-12 47.7 0.0 4.1e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 OWF35726.1 - 1.2e-09 38.2 1.5 3.1e-09 36.8 1.5 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OWF35726.1 - 0.0047 17.3 0.2 0.011 16.0 0.2 1.5 1 0 0 1 1 1 1 AAA domain zf-met PF12874.7 OWF35726.1 - 0.0059 17.0 0.1 0.017 15.5 0.1 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PhoH PF02562.16 OWF35726.1 - 0.015 14.7 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 OWF35726.1 - 0.06 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain OPA3 PF07047.12 OWF35727.1 - 3.4e-24 85.0 0.0 6.4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SKA1 PF07160.12 OWF35727.1 - 0.064 13.1 5.4 0.084 12.7 5.4 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Ribosomal_60s PF00428.19 OWF35727.1 - 0.21 12.2 4.1 0.29 11.7 3.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein C2 PF00168.30 OWF35728.1 - 2.2e-27 95.3 0.0 1.5e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain Corona_3 PF04694.12 OWF35730.1 - 0.17 12.3 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Coronavirus ORF3 protein LRR_6 PF13516.6 OWF35731.1 - 8.8e-32 106.5 33.7 3.6e-05 23.5 0.1 8.4 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 OWF35731.1 - 1.3e-08 34.3 10.1 5 8.1 0.0 7.9 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_4 PF12799.7 OWF35731.1 - 0.0007 19.9 32.6 0.73 10.3 2.2 5.8 1 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF35731.1 - 0.0019 17.9 32.5 0.37 10.6 8.4 6.0 4 3 2 6 6 6 4 Leucine rich repeat Peptidase_C14 PF00656.22 OWF35732.1 - 3.4e-22 79.6 0.0 4.9e-22 79.1 0.0 1.3 1 1 0 1 1 1 1 Caspase domain CLU PF13236.6 OWF35732.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Clustered mitochondria Rsm1 PF08600.10 OWF35733.1 - 0.044 14.0 0.4 0.11 12.7 0.4 1.7 1 0 0 1 1 1 0 Rsm1-like IFT43 PF15305.6 OWF35735.1 - 9.1e-39 132.7 4.6 9.1e-39 132.7 4.6 1.5 2 0 0 2 2 2 1 Intraflagellar transport protein 43 IQ PF00612.27 OWF35736.1 - 4.2e-10 38.5 22.1 2.1e-05 23.9 0.5 4.7 5 0 0 5 5 5 3 IQ calmodulin-binding motif PHINT_rpt PF14882.6 OWF35736.1 - 0.02 15.2 0.2 0.45 10.8 0.1 2.7 2 0 0 2 2 2 0 Phage-integrase repeat unit IQCJ-SCHIP1 PF15157.6 OWF35736.1 - 0.14 12.0 3.0 1.5 8.7 0.0 2.9 1 1 2 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF4574 PF15141.6 OWF35736.1 - 1.1 9.2 3.2 0.47 10.4 0.3 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 GDWWSH PF15667.5 OWF35737.1 - 1.4e-34 119.7 11.2 4.6e-34 118.0 11.2 1.7 1 1 0 1 1 1 1 Protein of unknown function with motif GDWWSH UL21a PF17636.2 OWF35737.1 - 0.031 14.3 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Viral Unique Long protein 21a TSP_1 PF00090.19 OWF35738.1 - 3.9e-14 52.6 65.6 1.3e-07 31.7 3.1 4.5 4 0 0 4 4 4 3 Thrombospondin type 1 domain Cadherin PF00028.17 OWF35739.1 - 3.8e-176 572.1 72.5 2.5e-13 50.3 0.0 28.6 27 3 1 28 28 28 25 Cadherin domain EGF PF00008.27 OWF35739.1 - 2.7e-09 37.2 68.3 1.4e-05 25.3 5.3 6.9 6 0 0 6 6 5 4 EGF-like domain TSP_1 PF00090.19 OWF35739.1 - 3.4e-06 27.2 22.8 1.2e-05 25.5 3.2 4.9 4 0 0 4 4 3 2 Thrombospondin type 1 domain EGF_3 PF12947.7 OWF35739.1 - 3.6e-05 23.9 15.2 3.6e-05 23.9 15.2 6.9 7 0 0 7 7 6 1 EGF domain Cadherin_3 PF16184.5 OWF35739.1 - 4.3e-05 23.5 59.2 0.046 13.7 0.5 16.6 17 2 1 18 18 18 3 Cadherin-like EGF_MSP1_1 PF12946.7 OWF35739.1 - 0.00018 21.5 4.8 0.00018 21.5 4.8 4.8 4 0 0 4 4 3 1 MSP1 EGF domain 1 DP-EP PF08985.11 OWF35739.1 - 0.018 15.2 0.0 0.018 15.2 0.0 6.7 5 0 0 5 5 5 0 DP-EP family hEGF PF12661.7 OWF35739.1 - 0.033 14.8 53.8 0.027 15.1 3.3 6.5 6 0 0 6 6 5 0 Human growth factor-like EGF Syndecan PF01034.20 OWF35739.1 - 0.09 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Syndecan domain B_lectin PF01453.24 OWF35739.1 - 0.17 12.4 0.5 26 5.4 0.1 4.2 4 0 0 4 4 4 0 D-mannose binding lectin EphA2_TM PF14575.6 OWF35739.1 - 0.82 10.6 2.6 0.64 10.9 0.3 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Striatin PF08232.12 OWF35740.1 - 1.1e-48 165.8 4.3 1.1e-48 165.8 4.3 2.8 2 2 0 2 2 2 1 Striatin family WD40 PF00400.32 OWF35740.1 - 3.2e-38 129.0 6.9 5.5e-08 33.3 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35740.1 - 4.4e-09 36.5 0.1 0.14 12.5 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF35740.1 - 0.01 14.5 1.8 1.5 7.3 0.1 3.0 1 1 0 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OWF35740.1 - 0.056 12.2 0.0 12 4.5 0.0 3.3 1 1 2 3 3 3 0 Nup133 N terminal like IalB PF06776.12 OWF35740.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein ATP-synt_E PF05680.12 OWF35740.1 - 0.2 12.0 3.0 2.8 8.4 0.2 2.7 2 0 0 2 2 2 0 ATP synthase E chain BUD22 PF09073.10 OWF35740.1 - 0.7 9.2 10.9 0.98 8.7 10.9 1.2 1 0 0 1 1 1 0 BUD22 DUF4482 PF14818.6 OWF35740.1 - 1.7 9.5 10.7 0.27 12.1 3.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) Clat_adaptor_s PF01217.20 OWF35741.1 - 1.7e-27 96.1 3.1 1.8e-27 96.0 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF273 PF03314.14 OWF35741.1 - 0.046 13.3 0.4 0.058 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF273 DUF3403 PF11883.8 OWF35745.1 - 0.00026 21.1 2.3 0.48 10.6 0.0 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF3403) Toluene_X PF03349.16 OWF35745.1 - 0.014 14.0 1.3 3.1 6.3 0.5 2.6 2 1 1 3 3 3 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) EF-hand_1 PF00036.32 OWF35746.1 - 1.2e-34 115.3 8.0 8.3e-08 31.2 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF35746.1 - 3.5e-30 104.2 1.4 5.7e-16 58.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF35746.1 - 8e-28 94.0 7.7 5.5e-08 32.1 0.2 4.3 3 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF35746.1 - 2.4e-22 77.3 9.1 1.2e-05 24.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF35746.1 - 2.5e-21 75.3 10.1 6e-10 38.8 0.4 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF35746.1 - 8.2e-12 45.3 0.2 4.5e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF35746.1 - 2.7e-08 33.7 1.0 0.0032 17.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF35746.1 - 1e-05 25.8 0.1 0.0093 16.3 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF35746.1 - 6e-05 23.9 0.0 0.00068 20.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 OWF35746.1 - 0.00057 18.6 0.0 0.00062 18.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Toprim_2 PF13155.6 OWF35746.1 - 0.0068 16.8 0.1 5.7 7.4 0.0 2.5 1 1 0 2 2 2 2 Toprim-like Dockerin_1 PF00404.18 OWF35746.1 - 0.016 15.4 8.3 9 6.6 8.4 3.1 1 1 1 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 OWF35746.1 - 0.019 14.9 0.5 0.67 9.9 0.5 3.0 1 1 0 1 1 1 0 Caleosin related protein DUF3349 PF11829.8 OWF35746.1 - 0.033 15.0 0.0 1.9 9.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Toprim PF01751.22 OWF35746.1 - 0.068 13.4 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Toprim domain Toprim_4 PF13662.6 OWF35746.1 - 0.11 13.0 0.4 5.5 7.5 0.0 2.8 1 1 3 4 4 4 0 Toprim domain PWI PF01480.17 OWF35748.1 - 1.3e-12 47.9 0.4 2.7e-12 46.8 0.4 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 OWF35748.1 - 7.5e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 OWF35749.1 - 6.7e-64 211.9 0.3 3.1e-25 87.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CLAMP PF14769.6 OWF35749.1 - 0.065 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 PHAT PF09246.10 OWF35750.1 - 1.7e-06 27.8 0.0 1.3e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 PHAT SAM_1 PF00536.30 OWF35750.1 - 0.0002 21.7 0.2 0.00049 20.5 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF35750.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GTP_cyclohydroI PF01227.22 OWF35751.1 - 1.2e-75 252.9 0.1 1.6e-75 252.4 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 OWF35751.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein WD-3 PF09765.9 OWF35752.1 - 9.9e-91 304.0 2.6 1.5e-90 303.4 2.6 1.3 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 OWF35752.1 - 1.3e-12 47.7 1.4 3.8e-12 46.2 1.4 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 OWF35752.1 - 0.027 14.7 0.2 0.027 14.7 0.2 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 OWF35752.1 - 0.099 13.0 4.8 0.32 11.4 4.8 1.9 1 0 0 1 1 1 0 Ring finger domain Peptidase_S28 PF05577.12 OWF35753.1 - 1.1e-124 416.6 0.0 1.2e-124 416.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OWF35753.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 Peptidase_S9 PF00326.21 OWF35753.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OWF35753.1 - 0.036 13.7 0.1 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-CCCH_2 PF14608.6 OWF35753.1 - 1.7 9.2 3.6 0.79 10.3 0.7 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger adh_short PF00106.25 OWF35754.1 - 1.9e-48 164.5 0.0 2.5e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF35754.1 - 4.7e-31 108.2 0.0 5.9e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF35754.1 - 4.3e-11 43.1 0.0 6.5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1499 PF07386.11 OWF35755.1 - 0.16 12.5 0.0 0.21 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) DUF1499 PF07386.11 OWF35757.1 - 6.9e-05 23.4 0.0 9.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Neur_chan_memb PF02932.16 OWF35758.1 - 0.023 14.8 2.9 0.041 13.9 2.9 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2207 PF09972.9 OWF35758.1 - 0.26 10.0 0.1 0.36 9.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CcmD PF04995.14 OWF35758.1 - 0.79 9.9 8.5 0.078 13.1 2.2 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) TMEM52 PF14979.6 OWF35758.1 - 0.97 9.3 7.5 4.3 7.3 0.2 3.6 1 1 1 3 3 3 0 Transmembrane 52 Xan_ur_permease PF00860.20 OWF35759.1 - 2.2e-72 243.9 33.2 4.3e-72 243.0 33.2 1.4 1 1 0 1 1 1 1 Permease family MFS_1 PF07690.16 OWF35760.1 - 1.5e-09 37.3 43.4 1.9e-07 30.3 16.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily UCR_UQCRX_QCR9 PF05365.12 OWF35760.1 - 8.8 6.4 6.2 13 5.8 0.6 3.1 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Abhydrolase_1 PF00561.20 OWF35761.1 - 2.6e-10 40.4 0.0 2.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF35761.1 - 0.00024 20.4 0.0 0.00024 20.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 OWF35761.1 - 0.0086 14.9 0.1 0.01 14.7 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OWF35761.1 - 0.059 12.8 0.1 0.066 12.7 0.1 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase family MtrB PF05440.12 OWF35761.1 - 0.15 12.5 0.1 0.21 12.0 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B TRAM_LAG1_CLN8 PF03798.16 OWF35762.1 - 6.7e-33 114.1 21.1 8.4e-33 113.8 21.1 1.1 1 0 0 1 1 1 1 TLC domain Peptidase_U4 PF03419.13 OWF35762.1 - 6.3 6.0 9.5 20 4.4 9.5 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA 7tm_2 PF00002.24 OWF35763.1 - 5.1e-51 173.3 12.1 7.8e-51 172.7 12.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF35763.1 - 3.8e-07 30.3 5.9 9.4e-07 29.0 5.9 1.7 1 0 0 1 1 1 1 Hormone receptor domain Fringe PF02434.16 OWF35764.1 - 4.5e-13 49.2 0.7 2e-12 47.1 0.2 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF35764.1 - 2.5e-07 30.7 0.0 0.0011 18.9 0.0 2.5 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 OWF35765.1 - 5.4e-13 49.0 0.3 3.1e-12 46.5 0.1 2.2 1 1 1 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OWF35765.1 - 1.3e-06 28.4 0.0 0.00026 20.9 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 OWF35766.1 - 2.9e-10 40.0 0.6 1.1e-09 38.1 0.6 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF35766.1 - 2.4e-09 37.3 0.0 2.9e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase WD40 PF00400.32 OWF35767.1 - 5.3e-10 39.7 12.2 0.0011 19.8 0.2 7.8 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35767.1 - 0.0033 17.7 0.0 10 6.5 0.0 4.7 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CBF PF03914.17 OWF35767.1 - 0.039 14.0 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 CBF/Mak21 family CUB PF00431.20 OWF35768.1 - 3.5e-11 43.4 0.0 7.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 OWF35768.1 - 7.5e-08 32.5 9.8 2.4e-07 30.9 9.8 1.9 1 1 0 1 1 1 1 Low-density lipoprotein receptor domain class A Shisa PF13908.6 OWF35768.1 - 0.0071 16.6 0.5 0.0071 16.6 0.5 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF3951 PF13131.6 OWF35768.1 - 0.055 13.7 3.5 0.39 11.0 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF4834 PF16118.5 OWF35768.1 - 0.17 12.8 0.6 0.52 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ATP_synt_H PF05493.13 OWF35768.1 - 0.79 10.2 3.6 1.1 9.8 0.7 2.2 2 0 0 2 2 2 0 ATP synthase subunit H SR-25 PF10500.9 OWF35768.1 - 0.95 9.0 13.0 1.3 8.6 13.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3509 PF12021.8 OWF35769.1 - 0.058 13.1 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) DUF898 PF05987.13 OWF35769.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Alpha_L_fucos PF01120.17 OWF35770.1 - 5.8e-114 381.2 5.3 7e-114 380.9 5.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF35770.1 - 2.9e-21 75.8 0.4 5.3e-21 75.0 0.4 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 OWF35770.1 - 0.095 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator VirE PF05272.11 OWF35771.1 - 0.00039 20.2 0.0 1.3e+02 2.2 0.0 7.0 6 1 3 9 9 9 0 Virulence-associated protein E AMP_N PF05195.16 OWF35771.1 - 0.0013 18.4 0.0 53 3.6 0.0 5.2 1 1 6 7 7 7 1 Aminopeptidase P, N-terminal domain Kelch_5 PF13854.6 OWF35771.1 - 1.4 9.0 5.1 2.1e+02 2.0 0.0 5.1 5 0 0 5 5 5 0 Kelch motif Defb50 PF17546.2 OWF35772.1 - 0.12 12.3 34.7 0.56 10.2 0.5 7.2 7 0 0 7 7 7 0 Beta defensin 50 VirE PF05272.11 OWF35772.1 - 0.26 11.0 0.0 79 2.9 0.0 4.0 5 1 0 5 5 5 0 Virulence-associated protein E DUF563 PF04577.14 OWF35772.1 - 1.1 9.3 2.8 70 3.4 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF563) RNA_pol_Rpc4 PF05132.14 OWF35773.1 - 7.3e-28 97.9 4.0 3.3e-27 95.8 0.6 3.2 3 1 0 3 3 3 1 RNA polymerase III RPC4 Alpha_L_fucos PF01120.17 OWF35774.1 - 2.2e-114 382.6 9.2 2.7e-114 382.3 9.2 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 OWF35774.1 - 0.081 13.1 0.3 0.34 11.1 0.0 2.2 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 6 Alpha_L_fucos PF01120.17 OWF35775.1 - 4e-115 385.0 9.4 5e-115 384.7 9.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF35775.1 - 3.1e-21 75.7 0.2 5.9e-21 74.8 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 OWF35775.1 - 0.0081 16.2 0.2 0.02 15.0 0.2 1.6 1 0 0 1 1 1 1 Lactococcus bacteriophage putative transcription regulator Methyltransf_16 PF10294.9 OWF35776.1 - 1.9e-23 83.1 1.2 5.7e-23 81.5 1.2 1.7 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OWF35776.1 - 1.2e-06 28.2 0.2 1.9e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OWF35776.1 - 0.0002 20.9 0.1 0.00041 19.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OWF35776.1 - 0.00036 21.2 0.2 0.00085 20.0 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF35776.1 - 0.00092 19.0 0.4 0.012 15.4 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF35776.1 - 0.0018 19.0 0.1 0.0071 17.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF35776.1 - 0.0067 17.1 0.1 0.017 15.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OWF35776.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 OWF35776.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 OWF35776.1 - 0.038 13.1 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.19 OWF35776.1 - 0.054 13.6 0.1 0.091 12.9 0.1 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Met_10 PF02475.16 OWF35776.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 OWF35776.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) VEFS-Box PF09733.9 OWF35777.1 - 6.6e-49 165.2 0.5 6.6e-49 165.2 0.5 2.3 2 0 0 2 2 2 1 VEFS-Box of polycomb protein Dimer_Tnp_hAT PF05699.14 OWF35777.1 - 0.00067 19.4 0.1 0.0018 18.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2 PF00096.26 OWF35777.1 - 2 9.0 6.1 13 6.5 6.1 2.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Phospholip_B PF04916.13 OWF35778.1 - 4.4e-174 579.9 7.3 5.3e-174 579.7 7.3 1.0 1 0 0 1 1 1 1 Phospholipase B Scm3 PF10384.9 OWF35778.1 - 0.023 14.4 0.2 0.46 10.3 0.1 3.0 3 0 0 3 3 3 0 Centromere protein Scm3 Trypsin PF00089.26 OWF35779.1 - 3.2e-57 193.9 0.0 4.5e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin F5_F8_type_C PF00754.25 OWF35779.1 - 4e-12 46.3 0.0 4.7e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain Trypsin_2 PF13365.6 OWF35779.1 - 1.4e-05 26.0 0.0 4.1e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Astacin PF01400.24 OWF35780.1 - 2.2e-57 193.8 2.0 3.1e-57 193.3 2.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 OWF35780.1 - 7.9e-35 120.1 0.8 1.4e-34 119.3 0.8 1.4 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF963 PF06131.11 OWF35780.1 - 0.17 11.3 7.0 0.52 9.8 7.0 1.8 1 1 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Ribosomal_S5 PF00333.20 OWF35782.1 - 7.5e-30 102.7 0.7 1.5e-29 101.7 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OWF35782.1 - 5.4e-25 86.6 0.1 1.1e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ATP_synth_reg PF14960.6 OWF35782.1 - 0.071 12.6 0.8 0.16 11.5 0.8 1.5 1 0 0 1 1 1 0 ATP synthase regulation FoP_duplication PF13865.6 OWF35782.1 - 1.9 9.1 16.6 4.4 7.9 16.6 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Actin PF00022.19 OWF35783.1 - 3.3e-146 487.0 0.0 1.1e-145 485.4 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 OWF35783.1 - 0.11 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain Glyco_tran_WecB PF03808.13 OWF35784.1 - 0.17 11.8 0.2 0.38 10.7 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Kinesin PF00225.23 OWF35786.1 - 1.8e-111 372.3 1.1 3.9e-111 371.2 1.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF35786.1 - 5.6e-26 91.3 0.6 1.2e-25 90.2 0.1 1.8 2 0 0 2 2 2 1 Microtubule binding WD40 PF00400.32 OWF35787.1 - 0.027 15.3 5.3 8.3 7.5 0.0 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat SPG48 PF14764.6 OWF35788.1 - 2.2e-38 131.4 3.4 2.2e-38 131.4 3.4 3.1 3 0 0 3 3 3 1 AP-5 complex subunit, vesicle trafficking U3snoRNP10 PF12397.8 OWF35788.1 - 0.93 9.9 9.6 1 9.7 0.3 4.1 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 10 CD225 PF04505.12 OWF35789.1 - 0.017 15.2 2.1 0.041 14.0 2.1 1.7 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF4199 PF13858.6 OWF35789.1 - 0.053 13.9 2.1 0.089 13.2 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PurK_C PF17769.1 OWF35790.1 - 0.076 12.7 0.0 3.4 7.4 0.0 2.5 1 1 1 2 2 2 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain Lactamase_B_2 PF12706.7 OWF35791.1 - 1.4e-35 122.7 0.0 1.9e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OWF35791.1 - 2.7e-13 50.1 0.0 3.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF35791.1 - 0.0004 20.5 0.2 0.013 15.5 0.6 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily tRNA_m1G_MT PF01746.21 OWF35792.1 - 2.1e-10 40.6 0.3 2.9e-09 36.9 0.0 2.7 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase WW PF00397.26 OWF35793.1 - 1.5e-09 37.8 1.2 3e-09 36.8 1.2 1.6 1 0 0 1 1 1 1 WW domain YL1 PF05764.13 OWF35793.1 - 0.03 14.4 1.6 0.041 14.0 1.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Adeno_E3_CR2 PF02439.15 OWF35795.1 - 1.3e-05 24.8 4.4 1.3e-05 24.8 4.4 1.8 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OWF35795.1 - 0.026 15.4 0.1 0.09 13.7 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OWF35795.1 - 0.089 13.6 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Orthoreo_P10 PF07204.11 OWF35795.1 - 0.1 12.6 2.8 0.052 13.5 1.2 1.4 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TMIE PF16038.5 OWF35795.1 - 0.32 10.9 3.7 0.67 9.8 3.7 1.5 1 0 0 1 1 1 0 TMIE protein DAP10 PF07213.11 OWF35795.1 - 6.6 6.8 10.0 1.3e+02 2.6 10.0 2.2 1 1 0 1 1 1 0 DAP10 membrane protein Pkinase PF00069.25 OWF35797.1 - 3.3e-75 252.9 0.0 4.4e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35797.1 - 2.2e-36 125.5 0.0 3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF35797.1 - 2.5e-06 27.0 0.0 6.7e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OWF35797.1 - 4.6e-06 26.1 0.0 2.1e-05 24.0 0.0 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OWF35797.1 - 0.0001 21.9 0.1 0.0001 21.9 0.1 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OWF35797.1 - 0.01 14.7 0.0 0.043 12.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OWF35797.1 - 0.042 13.8 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family AAA_6 PF12774.7 OWF35798.1 - 2.1e-156 519.9 0.0 1.7e-155 516.9 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF35798.1 - 1.2e-139 465.8 5.8 1.2e-139 465.8 5.8 3.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF35798.1 - 2.6e-112 375.0 0.0 6e-112 373.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF35798.1 - 3.6e-107 357.5 0.1 2.6e-106 354.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF35798.1 - 2.4e-92 308.1 8.8 2.8e-92 307.8 0.7 3.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF35798.1 - 5.4e-82 273.7 0.3 3.4e-79 264.6 0.0 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF35798.1 - 3.2e-65 218.9 0.1 1.3e-64 216.9 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF35798.1 - 2e-48 165.2 8.5 2e-48 165.2 8.5 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF35798.1 - 3.2e-47 159.5 0.0 1.2e-44 151.2 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF35798.1 - 8e-30 103.6 1.0 1.6e-28 99.4 0.1 3.5 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF35798.1 - 1.7e-18 67.0 0.0 2.9e-06 27.3 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OWF35798.1 - 1.2e-15 57.5 1.3 6.4e-15 55.2 0.7 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 OWF35798.1 - 1.4e-05 25.5 0.1 0.4 11.1 0.1 3.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF35798.1 - 8.1e-05 22.9 0.1 0.14 12.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 OWF35798.1 - 0.0014 19.0 0.0 0.71 10.2 0.0 3.6 3 0 0 3 3 2 1 AAA ATPase domain DUF4349 PF14257.6 OWF35798.1 - 0.0038 16.7 4.1 0.006 16.0 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) RNA_helicase PF00910.22 OWF35798.1 - 0.0048 17.3 0.0 6.2 7.3 0.0 3.3 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 OWF35798.1 - 0.015 15.8 0.0 0.69 10.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OWF35798.1 - 0.044 13.9 0.0 5.4 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 OWF35798.1 - 0.1 11.4 24.2 0.0061 15.5 2.5 3.7 3 0 0 3 3 3 0 Spc7 kinetochore protein ubiquitin PF00240.23 OWF35799.1 - 2.8e-09 36.6 0.2 8.5e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OWF35799.1 - 8e-05 22.4 0.0 0.0011 18.7 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IQ PF00612.27 OWF35799.1 - 0.012 15.3 3.1 0.036 13.8 3.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF4041 PF13250.6 OWF35799.1 - 0.026 14.4 0.1 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Hexokinase_2 PF03727.16 OWF35799.1 - 0.11 11.9 1.1 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 Hexokinase RNA_POL_M_15KD PF02150.16 OWF35799.1 - 0.3 11.0 1.0 0.74 9.7 1.0 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Ribosomal_L27e PF01777.18 OWF35799.1 - 6.5 7.2 9.1 1.9 8.9 4.5 2.6 2 1 0 2 2 2 0 Ribosomal L27e protein family SMC_N PF02463.19 OWF35800.1 - 6.5e-48 163.1 70.3 4e-46 157.2 70.3 4.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OWF35800.1 - 1.5e-23 83.3 0.3 8e-23 81.0 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OWF35800.1 - 9.1e-16 59.0 10.0 9.1e-16 59.0 10.0 7.7 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 OWF35800.1 - 4.7e-10 39.8 0.2 2.9e-07 30.6 0.1 5.1 4 3 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OWF35800.1 - 7.7e-10 39.0 32.8 7.7e-10 39.0 32.8 4.9 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 OWF35800.1 - 2.6e-07 30.3 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF35800.1 - 0.004 17.7 0.2 0.004 17.7 0.2 7.0 4 4 0 4 4 4 1 ABC transporter MCPsignal PF00015.21 OWF35800.1 - 0.013 15.4 1.2 0.013 15.4 1.2 6.4 4 1 1 6 6 6 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.9 OWF35800.1 - 0.022 15.0 0.2 0.022 15.0 0.2 9.9 7 3 3 10 10 10 0 Haemolysin XhlA SbcCD_C PF13558.6 OWF35800.1 - 0.033 14.4 0.2 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RIB43A PF05914.12 OWF35801.1 - 1e-148 495.2 54.1 1.1e-148 495.0 54.1 1.0 1 0 0 1 1 1 1 RIB43A PET PF06297.14 OWF35802.1 - 2.1e-38 130.5 0.5 5e-38 129.3 0.5 1.7 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 OWF35802.1 - 2.7e-23 81.9 56.2 4.2e-11 42.9 12.5 4.9 5 0 0 5 5 5 3 LIM domain Vasculin PF15337.6 OWF35802.1 - 0.38 11.6 3.2 0.75 10.7 0.0 2.8 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 zf-RING_UBOX PF13445.6 OWF35803.1 - 1.2e-07 31.6 7.3 1.2e-07 31.6 7.3 3.4 4 1 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF35803.1 - 2.2e-07 30.7 8.7 2.2e-07 30.7 8.7 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF35803.1 - 7.2e-07 29.3 17.9 2.2e-05 24.5 8.6 4.7 5 1 1 6 6 5 2 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF35803.1 - 4.1e-06 26.5 5.7 4.1e-06 26.5 5.7 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF35803.1 - 1.1e-05 25.4 9.8 1.1e-05 25.4 9.8 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF35803.1 - 1.7e-05 25.0 8.0 1.7e-05 25.0 8.0 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OWF35803.1 - 5.7e-05 23.0 7.8 5.7e-05 23.0 7.8 3.8 3 0 0 3 3 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF35803.1 - 0.00021 21.1 2.7 0.00021 21.1 2.7 3.9 3 2 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OWF35803.1 - 0.0018 18.1 10.8 0.0018 18.1 10.8 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 OWF35803.1 - 0.021 14.4 4.5 0.03 13.9 4.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sigma70_r3 PF04539.16 OWF35803.1 - 0.022 14.8 0.2 0.056 13.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-70 region 3 TA0956 PF11513.8 OWF35803.1 - 0.15 12.3 1.5 0.36 11.1 0.8 1.9 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 TetR_C_15 PF17918.1 OWF35803.1 - 0.23 12.2 0.4 23 5.8 0.1 2.6 3 0 0 3 3 2 0 Tetracyclin repressor-like, C-terminal domain zf-RING_11 PF17123.5 OWF35803.1 - 5.4 6.9 15.3 0.036 13.8 4.2 3.0 2 1 0 2 2 2 0 RING-like zinc finger SNF PF00209.18 OWF35804.1 - 4.3e-150 500.9 32.7 2.9e-119 399.1 17.9 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family Peptidase_M14 PF00246.24 OWF35805.1 - 1.8e-88 297.1 0.1 2.2e-88 296.8 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OWF35805.1 - 5.5e-11 42.7 0.1 1.1e-10 41.7 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Peptidase_M14 PF00246.24 OWF35806.1 - 2.3e-85 286.9 0.0 2.7e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OWF35806.1 - 9.6e-12 45.1 0.1 1.9e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide COQ9 PF08511.11 OWF35807.1 - 3e-33 113.4 0.4 7.7e-33 112.1 0.4 1.7 1 0 0 1 1 1 1 COQ9 DUF874 PF05917.11 OWF35808.1 - 0.0049 16.0 0.7 1.7 7.6 0.1 2.0 1 1 1 2 2 2 2 Helicobacter pylori protein of unknown function (DUF874) PPARgamma_N PF12577.8 OWF35808.1 - 0.0094 16.6 13.1 0.58 10.8 1.2 2.7 1 1 1 2 2 2 2 PPAR gamma N-terminal region DotU PF09850.9 OWF35808.1 - 0.08 12.7 1.9 3 7.5 0.1 2.1 2 0 0 2 2 2 0 Type VI secretion system protein DotU DUF1155 PF06633.11 OWF35808.1 - 0.19 11.3 8.0 36 4.0 0.0 6.7 2 2 4 7 7 7 0 Protein of unknown function (DUF1155) Prolactin_RP PF15172.6 OWF35809.1 - 0.038 13.6 2.1 6.9 6.4 0.0 3.3 1 1 2 4 4 4 0 Prolactin-releasing peptide DUF3849 PF12960.7 OWF35809.1 - 0.038 14.0 3.3 2.7 8.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3849) PPARgamma_N PF12577.8 OWF35809.1 - 0.2 12.3 9.3 2.8 8.6 2.7 2.1 1 1 1 2 2 2 0 PPAR gamma N-terminal region SRCR PF00530.18 OWF35810.1 - 2.7e-69 230.0 15.5 2.4e-23 82.5 1.4 3.2 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF35810.1 - 1.3e-16 60.9 5.3 0.00016 22.1 0.3 3.5 3 1 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF35810.1 - 1.3e-09 38.5 0.0 0.00073 20.0 0.0 3.3 3 0 0 3 3 3 3 Hepsin, SRCR domain ThiF PF00899.21 OWF35811.1 - 2.2e-75 253.2 0.0 3.7e-75 252.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 OWF35811.1 - 9e-23 80.7 0.1 9e-23 80.7 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 OWF35811.1 - 3.2e-08 33.8 4.6 0.0043 17.0 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OWF35811.1 - 4.8e-05 23.7 0.0 0.00017 21.9 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OWF35811.1 - 0.0081 16.2 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Phage_Gp23 PF10669.9 OWF35811.1 - 9.9 6.5 9.4 21 5.5 9.4 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MBOAT PF03062.19 OWF35812.1 - 3.7e-44 151.5 17.9 5.2e-44 151.0 17.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OWF35812.1 - 0.00017 21.8 5.2 0.00045 20.4 5.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RabGAP-TBC PF00566.18 OWF35813.1 - 3.3e-24 85.8 0.0 4.5e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ins145_P3_rec PF08709.11 OWF35814.1 - 2.2e-25 89.1 0.2 6.1e-24 84.4 0.3 2.6 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 OWF35814.1 - 1.6e-21 76.0 12.2 2.7e-19 68.9 1.9 5.0 5 0 0 5 5 5 2 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 OWF35814.1 - 2.1e-21 76.3 14.1 3.2e-19 69.2 1.8 3.4 3 0 0 3 3 3 2 RIH domain MIR PF02815.19 OWF35814.1 - 4.2e-15 56.1 0.6 4.3e-10 39.7 0.1 3.6 2 1 0 2 2 2 2 MIR domain Ion_trans PF00520.31 OWF35814.1 - 9.9e-07 28.2 12.0 2.3e-06 27.0 12.0 1.6 1 0 0 1 1 1 1 Ion transport protein AbiJ_NTD5 PF18865.1 OWF35814.1 - 0.0048 16.7 0.1 1 9.2 0.0 3.3 2 0 0 2 2 2 1 AbiJ N-terminal domain 5 DUF3899 PF13038.6 OWF35814.1 - 0.74 10.3 6.4 0.075 13.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Myb_DNA-bind_5 PF13873.6 OWF35815.1 - 2.8e-17 62.6 3.4 4.3e-17 62.0 3.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OWF35815.1 - 5.4e-07 29.9 0.4 9.4e-07 29.1 0.4 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF35815.1 - 0.00023 21.3 1.5 0.0005 20.3 0.8 2.0 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OWF35815.1 - 0.00079 19.6 0.8 0.0014 18.7 0.8 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OWF35815.1 - 0.0012 19.2 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like SNF PF00209.18 OWF35816.1 - 3.7e-187 623.2 37.2 4.3e-187 623.0 37.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family zf-C2H2_4 PF13894.6 OWF35817.1 - 1.2e-74 240.5 244.0 0.002 18.8 1.0 34.5 34 0 0 34 34 34 29 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF35817.1 - 2.3e-61 201.0 257.3 0.00019 21.7 1.4 34.3 34 1 0 34 34 34 26 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF35817.1 - 3.1e-19 68.4 237.3 7e-06 26.2 0.6 34.0 37 1 0 37 37 35 15 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF35817.1 - 6.2e-16 58.2 193.1 0.0062 16.8 1.7 30.2 31 0 0 31 31 31 13 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF35817.1 - 1.8e-14 53.3 239.5 0.00011 22.1 0.2 31.3 31 1 1 32 32 32 16 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF35817.1 - 0.0035 17.6 135.4 0.067 13.5 6.7 15.3 5 4 12 17 17 17 7 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 OWF35817.1 - 0.0068 16.7 2.6 0.0068 16.7 2.6 26.9 6 3 19 26 26 25 6 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 OWF35817.1 - 0.0096 16.2 8.3 0.0096 16.2 8.3 20.3 11 7 7 21 21 21 10 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OWF35817.1 - 0.05 13.4 0.1 0.05 13.4 0.1 23.0 25 1 1 26 26 26 0 zinc-finger C2H2-type zf_UBZ PF18439.1 OWF35817.1 - 0.08 12.6 0.1 0.08 12.6 0.1 23.5 26 1 1 27 27 27 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 OWF35817.1 - 2.6 8.6 206.8 0.28 11.6 1.0 28.8 32 0 0 32 32 31 0 Zinc-finger of C2H2 type PX PF00787.24 OWF35818.1 - 3.7e-11 43.0 0.1 5.1e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 PX domain IGF2_C PF08365.11 OWF35818.1 - 0.15 12.1 0.6 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide DUF4051 PF13260.6 OWF35818.1 - 0.21 11.3 2.0 1 9.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DIOX_N PF14226.6 OWF35819.1 - 4.2e-13 50.1 0.0 6.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OWF35819.1 - 1.9e-12 47.5 0.0 3.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RPE65 PF03055.15 OWF35820.1 - 3.9e-76 257.1 2.4 4.6e-76 256.9 2.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fam20C PF06702.12 OWF35821.1 - 6.5e-79 264.8 0.0 1e-78 264.1 0.0 1.3 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 Abhydrolase_1 PF00561.20 OWF35821.1 - 1.2e-07 31.7 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF35821.1 - 0.0051 17.5 0.0 0.013 16.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF35821.1 - 0.0067 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MFS_1 PF07690.16 OWF35822.1 - 2.3e-39 135.3 21.0 4e-39 134.5 21.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF35822.1 - 5.2e-17 61.8 25.4 2.7e-16 59.5 25.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 OWF35822.1 - 9.3e-05 21.9 2.6 0.00024 20.5 2.6 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF3611 PF12263.8 OWF35822.1 - 0.028 14.3 1.4 0.12 12.2 1.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF3792 PF12670.7 OWF35822.1 - 0.22 11.7 25.8 0.059 13.5 4.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3792) OATP PF03137.20 OWF35822.1 - 1 7.6 12.2 0.57 8.4 1.6 3.1 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family PBC PF03792.13 OWF35823.1 - 1.2e-93 312.1 0.6 1.8e-93 311.6 0.6 1.2 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 OWF35823.1 - 2e-19 69.1 2.4 2.6e-19 68.8 0.8 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF35823.1 - 4.3e-16 58.5 0.1 2.7e-15 56.0 0.0 2.4 3 0 0 3 3 3 1 Homeobox KN domain YdaS_antitoxin PF15943.5 OWF35823.1 - 0.002 17.9 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 OWF35823.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sec15 PF04091.12 OWF35823.1 - 0.04 13.3 0.2 0.065 12.6 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like CENP-B_N PF04218.13 OWF35823.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_26 PF13443.6 OWF35823.1 - 0.15 12.5 0.0 0.61 10.6 0.0 2.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DUF3391 PF11871.8 OWF35823.1 - 0.52 10.8 3.5 4.3 7.9 1.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Ribosomal_60s PF00428.19 OWF35823.1 - 2.8 8.6 7.3 20 5.9 1.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dynamin_M PF01031.20 OWF35824.1 - 1.8e-103 345.7 4.2 1.8e-103 345.7 4.2 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OWF35824.1 - 6.1e-53 179.3 0.0 1.6e-52 178.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OWF35824.1 - 1.1e-24 86.4 1.9 1.1e-24 86.4 1.9 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.29 OWF35824.1 - 8e-10 39.2 0.5 1.5e-09 38.3 0.5 1.4 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 OWF35824.1 - 0.00034 20.7 0.0 0.0011 19.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TetR_C_24 PF17932.1 OWF35824.1 - 0.00094 19.4 0.3 3.9 7.8 0.0 3.4 3 0 0 3 3 3 2 Tetracyclin repressor-like, C-terminal domain Aim21 PF11489.8 OWF35824.1 - 0.11 11.4 6.4 0.16 10.8 6.4 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 V-ATPase_G PF03179.15 OWF35825.1 - 3.3e-35 120.8 17.5 3.8e-35 120.6 17.5 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit BBS2_C PF14782.6 OWF35825.1 - 0.024 13.4 7.2 0.029 13.1 7.2 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal SHE3 PF17078.5 OWF35825.1 - 0.035 13.8 10.4 0.058 13.1 10.4 1.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 AC_N PF16214.5 OWF35825.1 - 0.036 13.2 0.8 0.056 12.6 0.7 1.4 1 1 1 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF3348 PF11828.8 OWF35825.1 - 0.037 13.7 3.0 0.04 13.6 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Orbi_NS3 PF01616.16 OWF35825.1 - 0.058 13.1 1.3 0.088 12.5 1.3 1.3 1 0 0 1 1 1 0 Orbivirus NS3 V-ATPase_G_2 PF16999.5 OWF35825.1 - 0.097 13.1 14.2 0.13 12.7 14.2 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF2827 PF10933.8 OWF35825.1 - 0.16 10.6 2.4 0.25 10.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) DUF883 PF05957.13 OWF35825.1 - 0.32 11.6 8.0 0.38 11.4 6.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 OWF35825.1 - 1.5 8.1 8.8 2 7.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 OWF35825.1 - 2 7.2 5.6 2.2 7.1 5.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Muted PF14942.6 OWF35825.1 - 3.9 7.8 14.4 0.99 9.7 8.1 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ATP-synt_B PF00430.18 OWF35825.1 - 9.9 6.3 21.0 56 3.8 20.6 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) TROVE PF05731.11 OWF35826.1 - 1.9e-29 103.0 2.5 3.6e-28 98.8 2.5 2.5 1 1 0 1 1 1 1 TROVE domain U3snoRNP10 PF12397.8 OWF35826.1 - 0.08 13.3 1.3 0.45 10.9 0.4 2.6 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Mab-21 PF03281.14 OWF35827.1 - 4.8e-17 62.2 0.0 9.8e-17 61.2 0.0 1.6 1 1 0 1 1 1 1 Mab-21 protein E1-E2_ATPase PF00122.20 OWF35828.1 - 4.8e-19 68.6 0.1 1.4e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OWF35828.1 - 3.2e-16 60.3 0.0 1.5e-09 38.4 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OWF35828.1 - 1.7e-05 24.8 0.0 4.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) FRG2 PF15315.6 OWF35828.1 - 0.0019 18.4 0.2 0.0033 17.7 0.2 1.3 1 0 0 1 1 1 1 Facioscapulohumeral muscular dystrophy candidate 2 Hydrolase_3 PF08282.12 OWF35828.1 - 0.022 14.5 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-C3HC4 PF00097.25 OWF35830.1 - 2.2e-06 27.4 6.9 2.2e-06 27.4 6.9 3.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF35830.1 - 3.2e-05 23.7 5.0 1.5 9.0 0.0 5.9 7 0 0 7 7 7 1 NHL repeat zf-RING_5 PF14634.6 OWF35830.1 - 4e-05 23.5 5.5 4e-05 23.5 5.5 3.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF35830.1 - 0.00013 21.9 5.9 0.00062 19.7 5.9 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF35830.1 - 0.00015 21.9 5.3 0.00015 21.9 5.3 3.5 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 OWF35830.1 - 0.00035 20.7 17.7 0.002 18.2 3.4 4.7 5 1 0 5 5 4 2 B-box zinc finger SGL PF08450.12 OWF35830.1 - 0.0011 18.6 0.0 0.0057 16.3 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4_2 PF13923.6 OWF35830.1 - 0.0017 18.1 3.0 0.0017 18.1 3.0 4.2 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) Lactonase PF10282.9 OWF35830.1 - 0.0055 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dynactin_p22 PF07426.11 OWF35830.1 - 0.032 14.1 4.3 0.073 12.9 4.3 1.6 1 0 0 1 1 1 0 Dynactin subunit p22 SBBP PF06739.11 OWF35830.1 - 0.077 13.0 1.2 0.35 10.9 0.0 2.5 3 0 0 3 3 2 0 Beta-propeller repeat DUF1664 PF07889.12 OWF35830.1 - 0.48 10.5 8.3 1.4 9.0 5.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 OWF35830.1 - 0.8 9.7 8.1 0.2 11.6 0.4 2.8 2 1 1 3 3 3 0 Prefoldin subunit zf-H2C2_2 PF13465.6 OWF35830.1 - 1.7 9.2 0.0 1.7 9.2 0.0 5.0 4 1 0 4 4 4 0 Zinc-finger double domain LIM PF00412.22 OWF35831.1 - 3.2e-31 107.4 19.8 1.3e-16 60.5 2.5 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 OWF35831.1 - 7.9e-19 67.3 2.0 1.6e-18 66.3 2.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF35831.1 - 1.7e-05 24.6 0.1 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OWF35831.1 - 0.023 14.1 0.1 0.047 13.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Furin-like_2 PF15913.5 OWF35831.1 - 1 9.6 12.6 0.11 12.7 7.9 1.9 1 1 0 1 1 1 0 Furin-like repeat, cysteine-rich Pkinase PF00069.25 OWF35832.1 - 1.1e-48 166.0 0.0 1.3e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF35832.1 - 3.6e-34 118.2 0.0 6.1e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF35832.1 - 3.5e-10 39.7 0.0 5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF35832.1 - 0.0044 16.4 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF35832.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF35832.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CAP_GLY PF01302.25 OWF35833.1 - 1.1e-16 60.6 0.1 2.5e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain DUF4378 PF14309.6 OWF35833.1 - 1.2e-05 25.8 1.2 4.3e-05 24.0 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4378) IQ PF00612.27 OWF35833.1 - 0.00092 18.8 0.4 0.0029 17.3 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF4711 PF15829.5 OWF35833.1 - 8.1 6.3 11.7 6.6 6.6 7.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) Gln-synt_C PF00120.24 OWF35834.1 - 8.7e-36 123.6 0.0 9.9e-15 54.4 0.0 4.1 4 0 0 4 4 4 4 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OWF35834.1 - 1e-28 98.9 0.0 8.2e-14 51.1 0.0 2.4 2 0 0 2 2 2 2 Glutamine synthetase, beta-Grasp domain Aminotran_4 PF01063.19 OWF35834.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Amino-transferase class IV Abhydrolase_1 PF00561.20 OWF35835.1 - 7e-48 163.5 0.0 9.9e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OWF35835.1 - 0.002 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 OWF35835.1 - 0.049 12.8 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PC4 PF02229.16 OWF35836.1 - 3.8e-13 48.8 0.7 2.4e-08 33.5 0.1 2.7 2 1 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) Phage_integrase PF00589.22 OWF35839.1 - 0.00041 20.2 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Ald_deCOase PF11266.8 OWF35840.1 - 0.081 12.6 0.1 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase Fer2_4 PF13510.6 OWF35841.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Sugar_tr PF00083.24 OWF35842.1 - 4.7e-28 98.3 17.4 1.3e-27 96.8 17.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF35842.1 - 9.3e-25 87.3 12.3 9.3e-25 87.3 12.3 2.0 3 0 0 3 3 3 1 Major Facilitator Superfamily Fzo_mitofusin PF04799.13 OWF35842.1 - 0.046 13.3 0.6 0.19 11.2 0.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region AOC_like PF18678.1 OWF35843.1 - 2.4 7.8 4.9 13 5.4 0.2 3.1 2 1 1 3 3 3 0 Allene oxide cyclase barrel like domain APG6 PF04111.12 OWF35847.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 1 0 1 1 1 0 Apg6 BARA domain Arfaptin PF06456.13 OWF35849.1 - 9.5e-83 277.3 10.2 1.7e-82 276.4 10.2 1.4 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.14 OWF35849.1 - 8e-45 154.1 25.8 1.9e-44 152.9 15.0 2.8 2 1 0 3 3 3 2 Islet cell autoantigen ICA69, C-terminal domain KxDL PF10241.9 OWF35849.1 - 0.058 13.7 2.9 13 6.1 0.0 3.6 2 1 1 3 3 3 0 Uncharacterized conserved protein ADAM_CR_2 PF17771.1 OWF35852.1 - 5.8e-14 52.4 8.3 1e-13 51.6 8.3 1.4 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin PF01421.19 OWF35852.1 - 1.2e-13 51.5 4.3 6e-13 49.1 0.2 3.0 1 1 1 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 OWF35852.1 - 7.7e-13 49.0 1.1 1.6e-12 48.0 1.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF35852.1 - 2.4e-10 41.0 0.3 6.9e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF35852.1 - 3.4e-08 33.6 0.6 8.4e-08 32.3 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF35852.1 - 1.1e-07 31.7 1.3 2.4e-07 30.6 1.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OWF35852.1 - 0.043 12.8 0.1 0.066 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Pep_M12B_propep PF01562.19 OWF35852.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide Peptidase_M10 PF00413.24 OWF35852.1 - 0.11 12.3 1.0 0.2 11.5 0.5 1.5 1 1 0 1 1 1 0 Matrixin SEA PF01390.20 OWF35854.1 - 5.8e-07 29.6 0.1 1.1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 SEA domain PDZ PF00595.24 OWF35855.1 - 2e-11 44.0 0.0 4.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF35855.1 - 4.6e-10 39.2 0.0 9.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF35855.1 - 0.00078 19.7 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain RE_NgoPII PF09521.10 OWF35855.1 - 0.042 13.0 0.1 0.072 12.2 0.1 1.3 1 0 0 1 1 1 0 NgoPII restriction endonuclease Defensin_big PF14862.6 OWF35856.1 - 1.1 9.7 9.3 9.1 6.7 9.3 2.2 1 1 0 1 1 1 0 Big defensin Cupin_8 PF13621.6 OWF35857.1 - 1.3e-22 80.7 2.2 1.8e-22 80.3 2.2 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OWF35857.1 - 6.1e-19 68.5 0.5 1.5e-18 67.3 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 OWF35857.1 - 0.0034 16.9 0.1 0.0085 15.6 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 OWF35857.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain 7tm_1 PF00001.21 OWF35858.1 - 2e-42 145.3 7.8 2.5e-42 145.0 7.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF35858.1 - 0.0013 18.5 13.3 0.002 17.9 13.2 1.3 1 1 0 1 1 1 1 Olfactory receptor GPHH PF16905.5 OWF35858.1 - 3.3 7.5 4.9 5.4 6.9 0.7 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Git3 PF11710.8 OWF35858.1 - 5.3 6.8 20.4 15 5.2 20.4 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 AAA_6 PF12774.7 OWF35859.1 - 1.4e-159 530.3 0.0 1.1e-157 524.1 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF35859.1 - 5.9e-149 496.5 7.4 5.9e-149 496.5 7.4 3.9 5 0 0 5 5 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF35859.1 - 2.4e-115 385.0 0.0 6.1e-114 380.4 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF35859.1 - 5e-104 347.2 0.2 2.3e-103 345.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF35859.1 - 4.1e-96 320.4 0.2 2.8e-94 314.3 1.2 3.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF35859.1 - 7.8e-83 276.4 0.0 5.9e-81 270.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF35859.1 - 3.4e-61 205.8 2.2 3.4e-59 199.3 0.2 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF35859.1 - 1.3e-50 172.4 9.0 1.3e-50 172.4 9.0 2.2 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF35859.1 - 2e-48 163.4 0.0 2.9e-45 153.2 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF35859.1 - 7e-36 123.2 0.3 6.9e-35 119.9 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OWF35859.1 - 2.5e-20 72.5 0.3 4.2e-19 68.6 0.1 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 OWF35859.1 - 2.1e-15 56.9 0.0 0.003 17.6 0.0 5.6 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF35859.1 - 8e-06 26.2 0.1 1.7 8.9 0.0 4.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 OWF35859.1 - 1.7e-05 25.2 1.4 3.9 7.9 0.1 5.1 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OWF35859.1 - 0.0037 17.6 0.7 8.7 6.8 0.0 4.5 4 0 0 4 4 3 0 RNA helicase AAA_18 PF13238.6 OWF35859.1 - 0.0088 16.6 0.1 0.31 11.6 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 OWF35859.1 - 0.0089 16.4 0.0 11 6.4 0.0 3.6 3 0 0 3 3 3 0 AAA ATPase domain EF-hand_6 PF13405.6 OWF35859.1 - 0.013 15.4 1.8 0.075 13.0 1.8 2.4 1 0 0 1 1 1 0 EF-hand domain RHSP PF07999.11 OWF35859.1 - 0.018 13.9 0.0 0.061 12.1 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon hot spot protein EF-hand_7 PF13499.6 OWF35859.1 - 0.041 14.3 2.1 0.2 12.2 0.9 3.0 2 0 0 2 2 1 0 EF-hand domain pair FliG_C PF01706.16 OWF35859.1 - 0.11 12.7 2.2 3.1 8.0 0.0 3.1 2 0 0 2 2 2 0 FliG C-terminal domain Bromo_coat PF01318.18 OWF35859.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Bromovirus coat protein EF-hand_1 PF00036.32 OWF35859.1 - 0.21 11.2 8.6 0.014 14.9 0.8 3.3 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 OWF35859.1 - 0.71 9.8 4.2 1.5 8.7 0.8 3.4 2 0 0 2 2 2 0 EF-hand domain pair T2SSE PF00437.20 OWF35859.1 - 0.82 8.7 4.8 1.6 7.8 0.0 3.4 5 0 0 5 5 5 0 Type II/IV secretion system protein TolA_bind_tri PF16331.5 OWF35859.1 - 1.4 9.0 4.6 16 5.6 1.3 3.8 3 0 0 3 3 3 0 TolA binding protein trimerisation ATG16 PF08614.11 OWF35859.1 - 1.6 8.9 17.5 0.1 12.8 1.1 3.7 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 OWF35860.1 - 0.00013 22.3 1.2 0.00044 20.5 0.6 2.0 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Blt1 PF12754.7 OWF35860.1 - 0.0049 17.2 1.1 0.007 16.7 1.1 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain ZapB PF06005.12 OWF35860.1 - 0.1 13.0 1.4 0.44 11.0 1.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 OWF35860.1 - 0.67 10.6 4.1 16 6.2 1.1 2.7 2 1 0 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 OWF35860.1 - 2 9.1 4.7 12 6.6 1.4 2.9 1 1 1 2 2 2 0 SlyX Lipase_GDSL_2 PF13472.6 OWF35861.1 - 0.002 18.5 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cathelicidins PF00666.17 OWF35861.1 - 0.17 12.2 0.4 17 5.8 0.3 2.3 1 1 1 2 2 2 0 Cathelicidin Metallophos PF00149.28 OWF35862.1 - 1.1e-12 48.9 3.5 1.9e-12 48.1 3.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF35862.1 - 1.7e-10 41.3 0.3 2.2e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain PapD-like PF14874.6 OWF35862.1 - 0.12 12.6 0.3 1.8 8.7 0.1 2.2 1 1 1 2 2 2 0 Flagellar-associated PapD-like PWWP PF00855.17 OWF35863.1 - 3.4e-17 62.6 0.1 3.4e-17 62.6 0.1 2.4 2 0 0 2 2 2 1 PWWP domain MBD PF01429.19 OWF35863.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain tRNA-synt_2c PF01411.19 OWF35864.1 - 8e-06 24.6 0.0 1.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OWF35864.1 - 8.7e-06 25.7 0.2 2.1e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF4364 PF14277.6 OWF35864.1 - 0.022 14.5 0.1 0.07 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) BST2 PF16716.5 OWF35864.1 - 0.1 13.2 0.1 0.4 11.3 0.1 2.0 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 CD225 PF04505.12 OWF35865.1 - 0.00011 22.2 1.1 0.00019 21.5 1.1 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Shisa PF13908.6 OWF35866.1 - 0.00073 19.8 0.2 0.0012 19.1 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Myc_target_1 PF15179.6 OWF35866.1 - 0.00078 19.4 0.9 0.00078 19.4 0.9 1.5 2 0 0 2 2 2 1 Myc target protein 1 MpPF26 PF07666.11 OWF35866.1 - 0.02 15.0 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 M penetrans paralogue family 26 EphA2_TM PF14575.6 OWF35866.1 - 0.031 15.2 0.0 0.095 13.6 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain V-set PF07686.17 OWF35866.1 - 0.066 13.4 0.1 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 OWF35867.1 - 6.1e-27 94.5 0.0 3.3e-26 92.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF35867.1 - 2.1e-23 83.0 0.0 4.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Activin_recp PF01064.23 OWF35867.1 - 1.6e-07 32.3 37.4 0.00023 22.2 11.2 4.3 4 0 0 4 4 4 2 Activin types I and II receptor domain Tachystatin_A PF11406.8 OWF35867.1 - 1.5 9.0 6.3 0.79 9.8 0.2 2.6 2 0 0 2 2 2 0 Antimicrobial peptide tachystatin A Toxin_TOLIP PF00087.21 OWF35867.1 - 4.6 7.6 32.5 0.19 12.0 13.2 3.0 2 0 0 2 2 2 0 Snake toxin and toxin-like protein Aminotran_1_2 PF00155.21 OWF35868.1 - 1e-44 153.2 0.0 1.3e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Arf PF00025.21 OWF35868.1 - 0.0029 17.1 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Hat1_N PF10394.9 OWF35869.1 - 4.8e-46 156.9 1.5 4.8e-46 156.9 1.5 2.0 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 OWF35869.1 - 3e-05 23.7 0.2 5.8e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 MOZ/SAS family Importin_rep PF18773.1 OWF35869.1 - 0.028 14.1 1.8 0.68 9.7 0.1 2.9 2 1 0 2 2 2 0 Importin 13 repeat NCD2 PF04905.13 OWF35869.1 - 0.039 13.9 1.7 0.072 13.1 1.7 1.4 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Acetyltransf_1 PF00583.25 OWF35869.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Mito_carr PF00153.27 OWF35870.1 - 8.3e-69 227.6 0.3 5.9e-24 83.8 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 OWF35870.1 - 1.1e-13 51.5 8.7 4.5e-05 23.8 0.3 5.0 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF35870.1 - 3e-13 48.3 5.7 6e-05 22.3 0.0 6.2 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 OWF35870.1 - 3.1e-09 36.0 6.5 0.0012 18.6 0.0 6.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 OWF35870.1 - 8.6e-05 22.3 1.0 0.12 12.3 0.1 4.4 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF35870.1 - 0.00034 20.0 3.2 0.0092 15.4 0.0 3.9 4 0 0 4 4 4 1 EF hand EF-hand_10 PF14788.6 OWF35870.1 - 0.07 13.0 2.8 8.1 6.4 0.0 3.2 3 0 0 3 3 3 0 EF hand SR-25 PF10500.9 OWF35871.1 - 0.46 10.1 4.2 0.67 9.5 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phage_coat PF09063.10 OWF35872.1 - 0.0063 16.5 7.8 38 4.3 0.0 5.2 1 1 5 6 6 6 0 Phage PP7 coat protein DUF2158 PF09926.9 OWF35872.1 - 0.031 14.0 7.5 32 4.3 0.0 4.9 3 1 2 5 5 5 0 Uncharacterized small protein (DUF2158) BofA PF07441.11 OWF35872.1 - 0.056 13.6 7.2 41 4.5 0.1 4.7 4 2 1 5 5 5 0 SigmaK-factor processing regulatory protein BofA Spo7_2_N PF15407.6 OWF35872.1 - 0.19 11.4 7.7 89 2.8 0.0 5.6 6 0 0 6 6 6 0 Sporulation protein family 7 DUF2550 PF10739.9 OWF35872.1 - 0.49 10.4 3.4 7.2 6.6 0.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2550) DUF4830 PF16112.5 OWF35873.1 - 0.011 16.1 5.6 1.8 9.1 0.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4830) DUF2335 PF10097.9 OWF35873.1 - 0.019 14.9 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) LLC1 PF14945.6 OWF35873.1 - 5.7 7.6 7.0 2.2 8.9 1.2 2.6 1 1 3 4 4 4 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RAP-1 PF03085.15 OWF35873.1 - 6.4 6.4 11.7 13 5.3 0.2 4.7 1 1 5 6 6 6 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_1N PF02870.15 OWF35873.1 - 6.8 7.6 6.1 67 4.4 0.1 3.5 2 1 3 5 5 5 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Tim44 PF04280.15 OWF35874.1 - 1.3e-19 70.8 0.1 2.5e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 OWF35874.1 - 0.01 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 MBA1-like protein W2 PF02020.18 OWF35875.1 - 1.9e-23 82.4 7.4 3.2e-22 78.4 4.4 3.4 2 1 0 2 2 2 2 eIF4-gamma/eIF5/eIF2-epsilon zf-C2HC_2 PF13913.6 OWF35876.1 - 3.6e-11 42.7 0.0 16 5.5 0.0 9.7 7 6 0 7 7 7 2 zinc-finger of a C2HC-type Thiolase_C PF02803.18 OWF35876.1 - 8.6e-05 22.2 0.1 2.5 7.7 0.0 3.9 1 1 3 4 4 4 3 Thiolase, C-terminal domain CdiI PF07262.11 OWF35876.1 - 0.00024 20.9 1.3 1.4 8.7 0.0 3.2 2 1 2 4 4 4 2 CDI immunity protein PcfJ PF14284.6 OWF35876.1 - 0.053 13.4 0.4 17 5.3 0.0 3.2 1 1 2 3 3 3 0 PcfJ-like protein zf-C2HC_2 PF13913.6 OWF35877.1 - 1.5e-06 28.0 0.1 8.3 6.4 0.0 8.4 10 4 0 10 10 10 1 zinc-finger of a C2HC-type Thiolase_C PF02803.18 OWF35877.1 - 0.0001 21.9 0.2 11 5.7 0.0 4.3 1 1 3 5 5 5 3 Thiolase, C-terminal domain CdiI PF07262.11 OWF35877.1 - 0.0024 17.6 2.2 6.4 6.5 0.1 3.5 2 1 3 5 5 5 3 CDI immunity protein DUF3225 PF11533.8 OWF35877.1 - 0.013 15.2 4.6 53 3.5 0.0 5.6 1 1 5 7 7 7 0 Protein of unknown function (DUF3225) PDZ_5 PF17817.1 OWF35877.1 - 0.079 13.2 9.1 31 5.0 0.1 5.1 2 2 2 5 5 5 0 PDZ domain DUF4840 PF16128.5 OWF35877.1 - 1.1 9.2 5.2 13 5.8 0.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4840) Peptidase_M2 PF01401.18 OWF35878.1 - 1.2e-203 677.9 5.9 1.5e-203 677.5 5.9 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF4108 PF13390.6 OWF35878.1 - 0.5 10.3 5.8 39 4.2 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4108) VWD PF00094.25 OWF35879.1 - 8.8e-68 227.5 15.6 8.4e-30 104.1 0.5 4.1 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 OWF35879.1 - 5e-26 90.9 38.0 6.2e-14 52.2 10.8 6.9 7 0 0 7 7 7 3 C8 domain Ldl_recept_a PF00057.18 OWF35879.1 - 4.7e-25 87.5 64.7 1.3e-09 38.1 12.6 12.4 12 1 1 13 13 13 4 Low-density lipoprotein receptor domain class A TIL PF01826.17 OWF35879.1 - 1.5e-18 66.8 87.2 9e-08 32.3 19.4 14.0 13 2 2 15 15 15 4 Trypsin Inhibitor like cysteine rich domain Autophagy_act_C PF03987.15 OWF35879.1 - 4.1e-06 27.3 4.5 2 9.1 0.2 4.1 3 0 0 3 3 3 3 Autophagocytosis associated protein, active-site domain VWC PF00093.18 OWF35879.1 - 0.0018 18.6 5.1 0.0018 18.6 5.1 15.8 10 6 3 13 13 13 3 von Willebrand factor type C domain T2SS-T3SS_pil_N PF13629.6 OWF35879.1 - 0.038 13.7 0.2 86 3.0 0.0 3.5 3 0 0 3 3 3 0 Pilus formation protein N terminal region PepSY PF03413.19 OWF35879.1 - 0.08 13.5 0.3 1.4e+02 3.1 0.0 3.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain MlaD PF02470.20 OWF35879.1 - 0.095 13.0 0.3 1.1e+02 3.2 0.0 3.6 3 0 0 3 3 3 0 MlaD protein HMG_box PF00505.19 OWF35880.1 - 1.2e-14 54.4 3.5 1.2e-14 54.4 3.5 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF35880.1 - 1.5e-08 35.1 2.2 1.5e-08 35.1 2.2 2.5 2 0 0 2 2 2 1 HMG-box domain DivIC PF04977.15 OWF35880.1 - 0.0025 17.5 1.5 0.0025 17.5 1.5 3.2 3 1 1 4 4 4 1 Septum formation initiator HAUS2 PF15003.6 OWF35880.1 - 0.012 15.4 1.1 0.073 12.8 0.5 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 CENP-H PF05837.12 OWF35880.1 - 3.2 8.2 8.1 0.76 10.2 0.2 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF2205 PF10224.9 OWF35880.1 - 7.6 6.6 8.9 1.6 8.8 1.0 3.0 2 1 1 3 3 3 0 Short coiled-coil protein DUF1308 PF07000.11 OWF35881.1 - 3.9e-43 147.2 0.0 6e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 OWF35881.1 - 2.1e-24 86.1 0.6 3.2e-24 85.5 0.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5614) DUF3856 PF12968.7 OWF35881.1 - 0.099 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) BTB PF00651.31 OWF35883.1 - 1.6e-20 73.4 0.0 3.1e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain VWA PF00092.28 OWF35884.1 - 4.1e-20 72.7 0.3 6e-20 72.2 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain PAN_1 PF00024.26 OWF35884.1 - 0.004 17.1 2.6 0.004 17.1 2.6 2.0 1 1 1 2 2 2 1 PAN domain DUF5475 PF17569.2 OWF35884.1 - 0.079 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5475) VWA PF00092.28 OWF35885.1 - 9.9e-23 81.3 0.2 1.2e-22 81.0 0.2 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF35885.1 - 0.0089 16.7 0.0 0.016 15.8 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain CWC25 PF12542.8 OWF35887.1 - 4.1e-15 56.5 1.0 4.1e-15 56.5 1.0 5.8 2 2 0 2 2 2 1 Pre-mRNA splicing factor Neur_chan_memb PF02932.16 OWF35888.1 - 1.5e-09 38.3 2.3 2.5e-07 31.0 1.7 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 OWF35889.1 - 7.1e-24 85.2 9.1 1.3e-20 74.5 8.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF35889.1 - 4.4e-21 75.3 0.0 7.3e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DAP PF15228.6 OWF35890.1 - 2.4e-28 99.2 5.6 2.7e-28 99.0 5.6 1.0 1 0 0 1 1 1 1 Death-associated protein PRC2_HTH_1 PF18118.1 OWF35891.1 - 1e-21 77.6 0.8 1e-21 77.6 0.8 2.7 3 1 0 3 3 3 1 Polycomb repressive complex 2 tri-helical domain SET PF00856.28 OWF35891.1 - 1.6e-18 67.7 0.6 1.1e-17 64.9 0.4 2.6 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 OWF35891.1 - 1.2e-11 44.8 16.5 1.2e-11 44.8 16.5 3.5 2 1 0 2 2 2 1 CXC domain TCR PF03638.15 OWF35891.1 - 2.7 8.4 35.9 5.6 7.4 14.2 3.3 1 1 1 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain UQ_con PF00179.26 OWF35892.1 - 1.2e-47 161.1 0.0 1.5e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF35892.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 OWF35892.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 UEV domain BPL_N PF09825.9 OWF35893.1 - 1.4e-53 182.3 0.0 2.1e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal SLX9 PF15341.6 OWF35894.1 - 5e-22 78.7 9.0 5e-22 78.7 9.0 2.5 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 TNFR_c6 PF00020.18 OWF35895.1 - 3.3e-26 91.4 60.7 1.1e-07 32.1 9.7 4.6 5 0 0 5 5 5 4 TNFR/NGFR cysteine-rich region Death PF00531.22 OWF35895.1 - 1.6e-13 50.6 0.1 2.8e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Death domain TNFR_16_TM PF18422.1 OWF35895.1 - 3.3e-12 46.2 0.2 8.4e-12 44.8 0.2 1.7 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain DUF3723 PF12520.8 OWF35895.1 - 0.014 14.1 0.1 0.021 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) p450 PF00067.22 OWF35896.1 - 1.7e-93 313.9 0.8 2e-93 313.6 0.8 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 OWF35897.1 - 1.5e-48 165.8 0.0 5.6e-45 154.0 0.0 2.2 2 0 0 2 2 2 2 Lipoxygenase Vps54 PF07928.12 OWF35898.1 - 7.4e-52 175.3 1.3 3.3e-51 173.2 0.2 2.7 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 OWF35898.1 - 9.1e-12 44.9 10.9 9.1e-12 44.9 10.9 2.7 2 1 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex STAT_alpha PF01017.20 OWF35898.1 - 0.027 14.4 0.1 0.027 14.4 0.1 3.3 4 0 0 4 4 4 0 STAT protein, all-alpha domain OMS28_porin PF03532.13 OWF35898.1 - 0.046 13.0 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 OMS28 porin DUF3023 PF11224.8 OWF35898.1 - 0.073 12.9 0.4 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) zf-C2H2_4 PF13894.6 OWF35898.1 - 5 8.2 7.3 0.86 10.6 0.3 3.6 2 1 1 3 3 3 0 C2H2-type zinc finger Claudin_3 PF06653.11 OWF35899.1 - 0.0012 18.8 16.6 0.0094 15.9 16.6 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Neur_chan_LBD PF02931.23 OWF35900.1 - 1.5e-26 93.2 0.4 1.9e-26 92.8 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF35900.1 - 2e-11 44.4 13.4 5.5e-11 43.0 7.5 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 OWF35901.1 - 3.1e-06 27.4 6.2 3.4e-06 27.3 6.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DuoxA PF10204.9 OWF35902.1 - 0.49 9.4 4.2 0.92 8.5 4.2 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF3450 PF11932.8 OWF35903.1 - 0.015 14.6 1.8 0.33 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cation_ATPase PF13246.6 OWF35903.1 - 0.08 13.0 1.1 0.27 11.3 1.1 2.0 1 1 0 1 1 1 0 Cation transport ATPase (P-type) Baculo_p74 PF04583.12 OWF35903.1 - 2.2 7.7 4.4 14 5.1 3.2 2.6 2 1 0 2 2 2 0 Baculoviridae p74 conserved region Spc7 PF08317.11 OWF35903.1 - 8.7 5.1 13.4 3.9 6.3 7.7 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein 7tm_1 PF00001.21 OWF35904.1 - 1.1e-34 119.9 17.6 1.7e-34 119.3 17.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 OWF35904.1 - 2.6e-18 65.5 0.1 2.1e-07 30.6 0.2 5.5 2 2 4 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 OWF35904.1 - 9e-12 45.1 0.2 3e-07 30.5 1.8 2.5 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF35904.1 - 2.1e-06 28.0 0.1 0.81 10.2 0.2 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) 7TM_GPCR_Srv PF10323.9 OWF35904.1 - 6.9e-05 22.3 12.4 7.9e-05 22.1 11.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv LRR_9 PF14580.6 OWF35904.1 - 0.0026 17.3 0.3 0.0061 16.1 0.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat Myb_DNA-bind_3 PF12776.7 OWF35905.1 - 0.073 14.1 0.1 0.073 14.1 0.1 3.4 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain EcsC PF12787.7 OWF35905.1 - 0.42 10.2 6.7 0.55 9.9 3.5 2.5 2 1 0 2 2 2 0 EcsC protein family TMF_TATA_bd PF12325.8 OWF35905.1 - 0.55 10.5 13.0 2 8.7 0.4 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spore_III_AE PF09546.10 OWF35905.1 - 4.3 6.5 9.7 4.9 6.3 1.6 2.4 1 1 1 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) TatD_DNase PF01026.21 OWF35906.1 - 2.3e-18 66.5 0.0 2.8e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase TBP PF00352.21 OWF35909.1 - 3.4e-45 151.9 0.2 6.7e-22 77.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) SF3b10 PF07189.11 OWF35910.1 - 2.5e-41 139.7 0.1 2.8e-41 139.5 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) RCC1 PF00415.18 OWF35911.1 - 9.2e-78 256.7 19.3 2e-12 47.5 0.3 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF35911.1 - 5.3e-33 112.1 23.7 5.2e-09 35.7 0.4 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 OWF35911.1 - 0.00049 19.9 0.0 2 8.1 0.0 3.5 4 0 0 4 4 4 2 TUP1-like enhancer of split Peptidase_C25_C PF03785.14 OWF35911.1 - 0.0013 18.5 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Peptidase family C25, C terminal ig-like domain SUKH-3 PF14433.6 OWF35911.1 - 0.033 14.7 2.5 0.96 9.9 0.0 3.4 5 0 0 5 5 5 0 SUKH-3 immunity protein HlyIII PF03006.20 OWF35912.1 - 8.7e-31 107.4 29.9 8.7e-31 107.4 29.9 1.5 2 0 0 2 2 2 1 Haemolysin-III related DUF1397 PF07165.11 OWF35914.1 - 6.3e-06 25.8 9.1 0.085 12.3 4.0 3.2 2 1 0 3 3 3 3 Protein of unknown function (DUF1397) zf-RING_2 PF13639.6 OWF35915.1 - 2.4e-12 47.0 6.2 3.5e-12 46.4 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF35915.1 - 1.5e-11 43.9 3.8 1.5e-11 43.9 3.8 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OWF35915.1 - 6.2e-08 32.5 2.7 1.2e-07 31.6 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF35915.1 - 6.4e-08 32.3 5.7 1.1e-07 31.6 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF35915.1 - 2.1e-07 30.7 4.4 3.8e-07 29.9 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF35915.1 - 5.1e-07 29.5 2.0 7.5e-07 28.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF35915.1 - 1.4e-05 25.2 9.4 0.00016 21.9 9.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF35915.1 - 4.7e-05 23.3 4.0 7.3e-05 22.6 3.1 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF35915.1 - 0.00018 21.3 2.5 0.00031 20.6 2.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OWF35915.1 - 0.0017 17.9 2.9 0.0028 17.2 2.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OWF35915.1 - 0.035 14.3 7.9 0.65 10.2 7.9 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 OWF35915.1 - 0.091 13.1 1.6 0.17 12.2 1.6 1.5 1 1 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 OWF35915.1 - 0.17 11.9 4.2 0.38 10.8 4.2 1.7 1 1 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 OWF35915.1 - 0.26 11.1 4.2 0.42 10.4 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 OWF35915.1 - 0.35 10.8 4.9 0.33 10.9 1.3 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 OWF35915.1 - 0.47 10.6 5.7 1.1 9.3 3.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OWF35915.1 - 0.53 10.5 4.5 2 8.6 4.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OWF35915.1 - 0.63 10.2 4.1 2.3 8.4 4.1 1.9 1 1 0 1 1 1 0 RING-variant domain F-box-like PF12937.7 OWF35916.1 - 5.3e-10 39.0 0.4 1.9e-09 37.3 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF35916.1 - 6.1e-05 22.8 0.4 6.1e-05 22.8 0.4 2.9 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 OWF35916.1 - 0.00014 21.8 1.5 0.00059 19.7 0.1 2.7 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 OWF35916.1 - 0.013 15.9 52.0 14 6.2 0.1 14.6 10 6 4 15 15 15 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF35916.1 - 0.74 10.0 0.0 0.74 10.0 0.0 9.9 15 0 0 15 15 15 0 Leucine Rich repeat Phosphodiest PF01663.22 OWF35917.1 - 1.5e-264 876.7 10.6 2.2e-91 307.1 0.6 3.2 3 0 0 3 3 3 3 Type I phosphodiesterase / nucleotide pyrophosphatase Endonuclease_NS PF01223.23 OWF35917.1 - 6.9e-21 75.1 0.0 1.5e-07 31.5 0.0 4.6 3 1 1 4 4 4 2 DNA/RNA non-specific endonuclease Metalloenzyme PF01676.18 OWF35917.1 - 1.5e-13 50.7 0.4 0.0011 18.4 0.0 3.3 3 0 0 3 3 3 3 Metalloenzyme superfamily Sulfatase PF00884.23 OWF35917.1 - 1.8e-11 44.0 8.5 0.0093 15.4 0.1 5.7 3 3 0 3 3 3 3 Sulfatase PglZ PF08665.12 OWF35917.1 - 2.9e-06 27.5 0.2 0.49 10.5 0.0 3.6 3 0 0 3 3 3 3 PglZ domain DnaJ PF00226.31 OWF35918.1 - 4.6e-24 84.3 0.2 3.1e-23 81.7 0.2 2.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 OWF35918.1 - 1.6e-09 37.8 6.0 1.6e-09 37.8 6.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF35918.1 - 1.2e-06 28.7 8.6 2.1e-06 27.9 2.9 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OWF35918.1 - 1.5e-05 25.4 5.2 0.027 15.3 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF35918.1 - 0.0054 17.1 8.1 0.11 13.0 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OWF35918.1 - 0.025 14.9 19.5 0.046 14.1 2.1 4.3 4 1 0 4 4 4 0 C2H2 type zinc-finger (2 copies) PriX PF18689.1 OWF35918.1 - 4.2 7.8 15.2 1.9 8.9 7.5 2.8 2 0 0 2 2 2 0 Primase X zf-C2H2_6 PF13912.6 OWF35918.1 - 5.5 7.1 8.7 1 9.5 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger BRCT_2 PF16589.5 OWF35919.1 - 4.9e-22 78.1 0.5 3e-09 37.2 0.0 3.6 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OWF35919.1 - 3.8e-14 52.8 3.2 2.1e-05 24.8 0.0 4.1 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OWF35919.1 - 5.3e-14 51.9 6.6 2.1e-09 37.2 1.0 3.5 3 0 0 3 3 3 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 OWF35919.1 - 4.5e-07 29.7 0.0 7.9e-05 22.5 0.0 3.3 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 OWF35919.1 - 0.00057 20.1 0.6 0.039 14.2 0.3 3.2 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OWF35919.1 - 0.11 12.5 2.6 16 5.6 0.0 3.5 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.16 OWF35920.1 - 0.00088 18.3 16.7 0.0038 16.2 10.0 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily VIT1 PF01988.19 OWF35920.1 - 0.016 15.0 0.3 0.071 13.0 0.3 2.1 1 0 0 1 1 1 0 VIT family VWA PF00092.28 OWF35921.1 - 2.4e-37 128.9 14.6 5.1e-24 85.5 2.8 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF35921.1 - 4.7e-23 81.9 3.2 2e-11 44.5 0.1 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OWF35921.1 - 5.2e-10 39.5 1.0 6e-08 32.8 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain EGF PF00008.27 OWF35921.1 - 1.3e-08 35.0 36.1 5.3e-05 23.4 7.7 3.8 3 0 0 3 3 3 3 EGF-like domain Sec23_trunk PF04811.15 OWF35921.1 - 9.8e-07 28.6 0.8 0.00028 20.5 0.1 2.5 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Ssl1 PF04056.14 OWF35921.1 - 0.0022 17.8 1.0 0.051 13.4 0.3 2.2 2 0 0 2 2 2 1 Ssl1-like hEGF PF12661.7 OWF35921.1 - 0.02 15.5 3.8 0.02 15.5 3.8 4.2 4 1 1 5 5 5 0 Human growth factor-like EGF EGF_3 PF12947.7 OWF35921.1 - 0.02 15.1 6.6 0.02 15.1 6.6 3.7 3 1 0 3 3 3 0 EGF domain EGF PF00008.27 OWF35922.1 - 1.6e-38 130.6 139.1 1.8e-05 24.9 10.0 9.1 8 2 0 8 8 8 8 EGF-like domain VWA PF00092.28 OWF35922.1 - 6.6e-38 130.7 9.5 8.5e-26 91.3 1.5 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF35922.1 - 2.4e-21 76.4 5.2 4.9e-13 49.7 0.5 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OWF35922.1 - 1.1e-09 38.4 1.2 2.1e-07 31.0 0.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain hEGF PF12661.7 OWF35922.1 - 8.6e-07 29.4 113.0 0.0086 16.7 5.3 10.0 8 2 1 9 9 9 7 Human growth factor-like EGF CODH_A_N PF18537.1 OWF35922.1 - 9.8 6.3 7.2 35 4.5 0.1 3.8 4 0 0 4 4 4 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Transglut_core2 PF13369.6 OWF35923.1 - 1.3e-35 122.2 0.0 2.1e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 OWF35923.1 - 4.2e-28 97.7 0.1 8.2e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Glyco_transf_7N PF13733.6 OWF35923.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DUF1899 PF08953.11 OWF35924.1 - 5.3e-30 103.1 0.1 1.8e-29 101.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OWF35924.1 - 1.2e-21 76.3 0.2 2.4e-21 75.4 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OWF35924.1 - 1.1e-10 41.9 4.8 7.9e-06 26.5 0.6 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF35924.1 - 0.00058 20.1 0.2 1.8 8.9 0.1 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Trimer_CC PF08954.11 OWF35924.1 - 0.15 11.6 0.5 0.41 10.2 0.5 1.7 1 0 0 1 1 1 0 Trimerisation motif FAST_2 PF08368.12 OWF35925.1 - 5.2e-08 33.6 0.0 2.4e-07 31.5 0.0 2.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 OWF35925.1 - 0.28 11.2 4.3 1.8 8.6 0.0 3.7 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Cupin_2 PF07883.11 OWF35926.1 - 2.1e-09 37.0 0.0 2.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 OWF35926.1 - 0.0099 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 OWF35926.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Na_Ca_ex PF01699.24 OWF35927.1 - 3.1e-24 85.7 13.6 3.1e-24 85.7 13.6 2.0 3 0 0 3 3 3 1 Sodium/calcium exchanger protein Ytca PF17090.5 OWF35927.1 - 0.097 13.2 0.0 0.097 13.2 0.0 3.2 3 1 1 4 4 4 0 Uncharacterised protein family DUF3169 PF11368.8 OWF35927.1 - 0.33 10.4 0.0 0.33 10.4 0.0 3.2 4 1 1 5 5 5 0 Protein of unknown function (DUF3169) Il2rg PF15874.5 OWF35928.1 - 6.7e-28 96.8 0.1 1.1e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain Ribosomal_L29 PF00831.23 OWF35929.1 - 5.1 7.1 5.9 1.1 9.3 0.6 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein zf-MYND PF01753.18 OWF35930.1 - 1.3e-05 25.1 8.1 1.3e-05 25.1 8.1 2.4 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 OWF35930.1 - 0.44 10.5 7.5 1.1 9.2 7.5 1.7 1 0 0 1 1 1 0 HIT zinc finger C1_2 PF03107.16 OWF35930.1 - 3.2 8.1 5.5 4.2 7.8 2.1 2.8 2 0 0 2 2 2 0 C1 domain MIF PF01187.18 OWF35931.1 - 8.9e-14 51.8 0.1 1e-13 51.6 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) SpoIIID PF12116.8 OWF35931.1 - 0.012 15.7 0.1 0.08 13.0 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein D Ribosomal_S4Pg PF11993.8 OWF35931.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) Efg1 PF10153.9 OWF35932.1 - 0.096 13.0 1.3 0.23 11.8 1.3 1.6 1 0 0 1 1 1 0 rRNA-processing protein Efg1 SNARE PF05739.19 OWF35932.1 - 0.15 12.1 2.9 6.9 6.7 0.0 3.4 3 0 0 3 3 3 0 SNARE domain TPR_2 PF07719.17 OWF35932.1 - 0.24 11.6 2.1 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4537 PF15057.6 OWF35933.1 - 2e-84 279.6 1.3 2.2e-30 105.2 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 OWF35933.1 - 9.1e-08 31.8 0.1 0.24 11.3 0.0 4.7 5 0 0 5 5 5 2 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 OWF35933.1 - 0.00036 20.1 1.2 0.2 11.3 0.1 3.6 3 0 0 3 3 3 1 Jumonji domain-containing protein 2A Tudor domain 53-BP1_Tudor PF09038.10 OWF35933.1 - 0.00073 19.5 0.6 0.67 9.9 0.1 3.7 2 1 2 4 4 4 1 Tumour suppressor p53-binding protein-1 Tudor Prot_ATP_ID_OB PF16450.5 OWF35933.1 - 0.011 15.7 0.0 0.28 11.2 0.0 2.7 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Agenet PF05641.12 OWF35933.1 - 0.03 14.8 0.1 2.3 8.7 0.0 3.6 3 0 0 3 3 3 0 Agenet domain TUDOR_5 PF18359.1 OWF35933.1 - 0.047 13.4 0.1 7.1 6.4 0.0 4.1 5 0 0 5 5 5 0 Histone methyltransferase Tudor domain 1 HupF_HypC PF01455.18 OWF35933.1 - 0.098 12.8 0.0 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 HupF/HypC family OmpH PF03938.14 OWF35933.1 - 0.28 11.5 17.0 0.73 10.2 17.0 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 OWF35933.1 - 0.74 9.0 15.0 1.2 8.3 15.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Hamartin PF04388.12 OWF35933.1 - 3.8 6.1 35.4 5.2 5.6 35.4 1.1 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 OWF35933.1 - 4.6 6.3 39.9 7.3 5.7 39.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4407 PF14362.6 OWF35933.1 - 6.3 6.1 7.9 11 5.3 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VWA_3 PF13768.6 OWF35934.1 - 5.5e-24 84.9 0.0 8.4e-18 64.8 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 OWF35934.1 - 4.4e-11 43.3 0.0 1.4e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF35934.1 - 2.8e-06 27.9 0.0 1.7e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF655 PF04919.12 OWF35934.1 - 0.078 12.9 0.1 0.3 11.0 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF655) DHHC PF01529.20 OWF35935.1 - 1.2e-36 125.8 13.4 1.2e-36 125.8 13.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Reticulon PF02453.17 OWF35935.1 - 0.0036 17.3 1.4 0.049 13.6 0.2 2.5 2 0 0 2 2 2 1 Reticulon Endonuclease_5 PF04493.14 OWF35936.1 - 3.2e-65 219.5 0.0 4e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 OWF35936.1 - 0.0041 17.0 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal DUF99 PF01949.16 OWF35936.1 - 0.063 12.7 0.0 0.63 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF99 Nup54_C PF18437.1 OWF35936.1 - 0.14 12.1 1.0 0.34 10.9 1.0 1.7 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain TSP_1 PF00090.19 OWF35937.1 - 2.7e-13 49.9 5.2 9.3e-13 48.2 5.2 2.0 1 0 0 1 1 1 1 Thrombospondin type 1 domain CUB PF00431.20 OWF35937.1 - 2.1e-07 31.3 0.0 6.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 CUB domain PRIMA1 PF16101.5 OWF35937.1 - 0.018 15.1 0.2 0.018 15.1 0.2 2.5 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Rax2 PF12768.7 OWF35937.1 - 4.5 6.7 6.0 1.2 8.6 1.1 2.4 2 1 0 2 2 2 0 Cortical protein marker for cell polarity ydhR PF08803.11 OWF35938.1 - 1 9.3 9.7 24 4.9 0.1 5.5 5 3 3 8 8 8 0 Putative mono-oxygenase ydhR DUF4773 PF15998.5 OWF35938.1 - 6.3 7.4 11.3 2.6 8.6 0.4 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4773) DUF4773 PF15998.5 OWF35939.1 - 1.2 9.7 14.8 18 5.9 0.4 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4773) Bactofilin PF04519.13 OWF35940.1 - 4.4e-10 39.7 49.0 0.00053 20.2 6.2 6.0 1 1 5 6 6 6 6 Polymer-forming cytoskeletal 2OG-FeII_Oxy PF03171.20 OWF35940.1 - 0.15 12.6 1.5 1.7e+02 2.8 0.0 4.5 3 3 2 5 5 5 0 2OG-Fe(II) oxygenase superfamily DUF2807 PF10988.8 OWF35941.1 - 0.0012 18.6 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain Ion_trans PF00520.31 OWF35942.1 - 4.7e-244 805.4 97.3 6.8e-72 241.6 11.7 4.1 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.13 OWF35942.1 - 3.8e-15 56.7 2.7 3.8e-15 56.7 2.7 3.3 3 1 0 3 3 3 1 Sodium ion transport-associated PKD_channel PF08016.12 OWF35942.1 - 2.2e-08 33.2 90.5 0.0033 16.2 5.6 10.1 6 3 2 8 8 8 7 Polycystin cation channel GPHH PF16905.5 OWF35942.1 - 0.0018 18.0 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Na_trans_cytopl PF11933.8 OWF35942.1 - 0.0067 16.3 10.4 0.0079 16.0 4.5 2.7 2 1 0 2 2 2 1 Cytoplasmic domain of voltage-gated Na+ ion channel COX16 PF14138.6 OWF35942.1 - 0.11 13.0 0.2 2.1 8.9 0.0 3.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 IQ PF00612.27 OWF35942.1 - 1 9.3 3.6 2.6 8.1 3.6 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Glyco_hydro_38N PF01074.22 OWF35943.1 - 7.4e-78 261.8 2.2 1e-77 261.4 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF35943.1 - 1.3e-33 116.9 0.0 3.2e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF35943.1 - 2.2e-19 69.4 0.1 4.9e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Spec3 PF15795.5 OWF35944.1 - 4.1e-31 107.4 10.0 6e-31 106.8 10.0 1.2 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein HemY_N PF07219.13 OWF35944.1 - 0.068 13.4 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 HemY protein N-terminus DUF1218 PF06749.12 OWF35944.1 - 0.12 12.9 1.5 0.23 12.0 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) BSP_II PF05432.11 OWF35944.1 - 9.5 5.8 13.2 15 5.1 13.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TTL PF03133.15 OWF35945.1 - 2.7e-89 299.2 0.6 6.5e-89 297.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF35945.1 - 6.3e-06 25.6 2.0 0.0086 15.4 0.0 2.9 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF35945.1 - 0.0021 17.3 0.0 0.19 10.9 0.0 2.6 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp Homeodomain PF00046.29 OWF35946.1 - 1.5e-18 66.3 5.7 2.5e-18 65.6 5.7 1.3 1 0 0 1 1 1 1 Homeodomain DUF1325 PF07039.11 OWF35947.1 - 0.00019 21.5 12.5 0.24 11.5 0.4 3.9 1 1 2 4 4 4 3 SGF29 tudor-like domain SIT PF15330.6 OWF35947.1 - 0.02 15.3 9.4 2.1 8.8 0.6 3.2 1 1 2 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Alg14 PF08660.11 OWF35947.1 - 0.041 13.8 1.9 9.2 6.2 0.1 3.7 1 1 1 4 4 4 0 Oligosaccharide biosynthesis protein Alg14 like PHD_2 PF13831.6 OWF35947.1 - 0.071 12.7 17.0 12 5.5 0.1 6.0 6 0 0 6 6 6 0 PHD-finger Alpha_E1_glycop PF01589.16 OWF35947.1 - 0.13 10.9 7.9 7.5 5.1 0.2 3.3 1 1 2 4 4 4 0 Alphavirus E1 glycoprotein IL17R_fnIII_D2 PF16578.5 OWF35947.1 - 2.4 8.7 12.4 16 6.1 0.6 3.6 1 1 2 3 3 3 0 Interleukin 17 receptor D DUF4573 PF15140.6 OWF35948.1 - 0.0022 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) PMP22_Claudin PF00822.20 OWF35948.1 - 0.08 12.8 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Heliorhodopsin PF18761.1 OWF35948.1 - 0.24 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 Heliorhodopsin Trypsin PF00089.26 OWF35949.1 - 6.9e-10 39.1 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin CCD48 PF15799.5 OWF35950.1 - 1.8 6.7 4.3 0.86 7.8 0.5 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 48 MLD PF11647.8 OWF35950.1 - 2.4 8.5 9.0 16 5.8 0.1 3.6 2 2 1 3 3 3 0 Membrane Localization Domain Glyco_transf_10 PF00852.19 OWF35951.1 - 1.1e-43 149.0 1.7 1.1e-43 149.0 1.7 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF35951.1 - 2.9e-20 72.8 0.1 5.7e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal zf-RING_2 PF13639.6 OWF35952.1 - 4.7e-16 58.9 22.5 6.9e-09 35.9 5.6 3.4 3 0 0 3 3 3 3 Ring finger domain zf-RING_5 PF14634.6 OWF35952.1 - 4.1e-13 49.0 21.0 6.9e-07 29.1 6.4 3.5 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_11 PF17123.5 OWF35952.1 - 1.4e-12 47.1 15.4 2.1e-05 24.1 3.8 3.8 3 0 0 3 3 3 3 RING-like zinc finger Prok-RING_4 PF14447.6 OWF35952.1 - 2.4e-12 46.5 13.3 2.3e-05 24.2 3.3 3.6 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OWF35952.1 - 4.8e-11 42.3 16.3 9.2e-06 25.4 4.2 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF35952.1 - 5.5e-11 42.6 17.5 3.5e-06 27.2 3.9 3.4 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF35952.1 - 2.6e-08 33.8 23.9 1.2e-05 25.3 3.2 4.2 3 1 1 4 4 4 2 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF35952.1 - 5.9e-08 32.7 14.6 0.00067 19.7 3.3 3.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OWF35952.1 - 6.5e-08 32.3 20.2 5.4e-05 23.0 5.2 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF35952.1 - 3.7e-07 29.9 26.1 0.0017 18.2 6.5 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.27 OWF35952.1 - 1.9e-05 24.0 2.0 5.3e-05 22.6 2.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zn_ribbon_17 PF17120.5 OWF35952.1 - 0.00021 20.9 17.0 0.022 14.3 3.1 3.3 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 OWF35952.1 - 0.00037 20.6 11.3 0.13 12.4 2.9 3.3 3 0 0 3 3 3 2 Zinc-binding RING-finger zf-RING_4 PF14570.6 OWF35952.1 - 0.0024 17.6 12.4 0.3 10.9 3.7 3.6 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 OWF35952.1 - 0.0035 17.3 3.4 0.51 10.4 0.1 3.1 3 0 0 3 3 3 1 Transposase zinc-ribbon domain PHD PF00628.29 OWF35952.1 - 0.0039 17.0 15.2 0.2 11.6 4.1 3.2 3 0 0 3 3 3 2 PHD-finger Zf_RING PF16744.5 OWF35952.1 - 0.028 14.5 15.4 0.13 12.4 3.1 3.5 3 1 0 3 3 3 0 KIAA1045 RING finger Pellino PF04710.14 OWF35952.1 - 0.03 13.0 5.0 2.1 6.9 0.6 3.0 3 0 0 3 3 3 0 Pellino ALMT PF11744.8 OWF35952.1 - 0.17 10.7 1.5 0.43 9.3 1.5 1.7 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-C3HC4_4 PF15227.6 OWF35952.1 - 0.73 10.1 21.1 0.12 12.6 1.9 3.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zinc_ribbon_11 PF11682.8 OWF35952.1 - 1 9.4 6.8 0.74 9.8 1.2 3.3 3 1 0 3 3 3 0 Probable zinc-ribbon zf-RING-like PF08746.11 OWF35952.1 - 3.6 8.0 23.0 0.31 11.4 5.3 3.6 3 1 0 3 3 3 0 RING-like domain zf-Nse PF11789.8 OWF35952.1 - 3.8 7.4 13.5 7.8 6.4 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Sof1 PF04158.14 OWF35953.1 - 9.7e-32 109.1 10.8 1.8e-31 108.2 10.8 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 OWF35953.1 - 1.1e-22 79.8 7.6 1.6e-05 25.6 0.4 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 OWF35953.1 - 5.7e-07 29.6 0.0 0.02 14.8 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OWF35953.1 - 5.8e-06 26.5 0.1 0.17 12.2 0.0 4.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4129 PF13559.6 OWF35953.1 - 0.17 12.1 0.2 23 5.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) TFIIS_M PF07500.14 OWF35955.1 - 6.2e-34 116.8 0.9 6.2e-34 116.8 0.9 3.3 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 OWF35955.1 - 2.5e-26 92.4 0.0 1e-25 90.4 0.0 2.1 2 0 0 2 2 2 1 SPOC domain BRK PF07533.16 OWF35955.1 - 2.8e-10 39.6 0.0 7.6e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 BRK domain PHD PF00628.29 OWF35955.1 - 6.8e-10 38.7 12.9 6.8e-10 38.7 12.9 2.6 2 0 0 2 2 2 1 PHD-finger DEAD PF00270.29 OWF35956.1 - 5.6e-51 172.8 0.0 1.3e-50 171.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF35956.1 - 8e-25 87.3 0.2 2.3e-23 82.6 0.2 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OWF35956.1 - 2.1e-19 69.5 12.0 2.1e-19 69.5 12.0 4.8 6 0 0 6 6 6 1 DBP10CT (NUC160) domain mRNA_cap_enzyme PF01331.19 OWF35957.1 - 2.4e-68 229.8 0.0 3.7e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OWF35957.1 - 6.6e-20 71.8 0.2 1.6e-19 70.5 0.1 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 OWF35957.1 - 1.4e-11 44.3 0.0 4e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 OWF35957.1 - 0.0002 21.0 0.0 0.026 14.2 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Y_phosphatase2 PF03162.13 OWF35957.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Shugoshin_C PF07557.11 OWF35958.1 - 3.6e-05 23.5 0.9 3.6e-05 23.5 0.9 4.9 4 0 0 4 4 4 1 Shugoshin C terminus TIR_2 PF13676.6 OWF35959.1 - 1e-19 71.3 0.4 3e-19 69.8 0.1 2.0 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 OWF35959.1 - 0.0011 18.8 0.0 0.0067 16.2 0.0 2.2 2 0 0 2 2 2 1 TIR domain Arm PF00514.23 OWF35959.1 - 0.0016 18.4 0.1 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat IRF-2BP1_2 PF11261.8 OWF35959.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Myb_DNA-bind_7 PF15963.5 OWF35959.1 - 0.031 14.2 0.1 0.078 12.9 0.1 1.6 1 0 0 1 1 1 0 Myb DNA-binding like DUF3791 PF12668.7 OWF35960.1 - 0.0057 16.7 0.6 96 3.1 0.0 4.9 1 1 7 8 8 8 0 Protein of unknown function (DUF3791) Herpes_UL42 PF02282.16 OWF35960.1 - 0.12 12.2 5.2 35 4.2 0.1 4.0 1 1 3 4 4 4 0 DNA polymerase processivity factor (UL42) Lir1 PF07207.11 OWF35960.1 - 0.31 11.3 0.8 1.4e+02 2.7 0.0 4.9 1 1 5 7 7 7 0 Light regulated protein Lir1 RNA_pol_L_2 PF13656.6 OWF35960.1 - 0.57 10.0 27.7 8.7 6.2 0.2 6.1 1 1 8 9 9 9 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Tubulin PF00091.25 OWF35961.1 - 2.4e-62 210.7 0.0 3.4e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF35961.1 - 3.7e-29 101.4 0.0 6.2e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 OWF35961.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Bombesin PF02044.17 OWF35961.1 - 0.081 13.0 1.2 0.23 11.6 1.2 1.7 1 0 0 1 1 1 0 Bombesin-like peptide AAA_11 PF13086.6 OWF35963.1 - 3.5e-15 56.5 0.9 6.8e-15 55.6 0.6 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF35963.1 - 6.8e-06 26.5 0.0 2.2e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OWF35963.1 - 0.00053 19.3 0.5 0.0014 17.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OWF35963.1 - 0.0007 19.6 0.7 0.0032 17.5 0.7 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OWF35963.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OWF35963.1 - 0.0052 16.4 2.1 0.014 14.9 2.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 OWF35963.1 - 0.0085 16.4 0.6 0.072 13.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 OWF35963.1 - 0.014 14.8 0.0 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 OWF35963.1 - 0.017 15.6 0.2 0.37 11.2 0.2 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF35963.1 - 0.035 14.5 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 OWF35963.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 OWF35963.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OWF35963.1 - 0.098 12.4 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OWF35965.1 - 4.9e-17 62.6 7.9 4.1e-15 56.3 7.9 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF35965.1 - 1.8e-05 25.1 0.1 0.0001 22.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OWF35965.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OWF35965.1 - 0.0011 18.7 0.1 0.0027 17.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OWF35965.1 - 0.0052 16.8 0.2 0.0052 16.8 0.2 3.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF35965.1 - 0.014 15.7 0.6 0.13 12.6 0.2 2.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 OWF35965.1 - 0.016 15.6 0.9 0.74 10.2 0.3 3.1 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OWF35965.1 - 0.016 14.6 0.1 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 OWF35965.1 - 0.028 14.2 0.0 0.1 12.4 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OWF35965.1 - 0.093 13.1 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 OWF35965.1 - 0.14 11.8 0.3 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Trypsin_2 PF13365.6 OWF35967.1 - 2.2e-12 48.1 0.0 4.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF35967.1 - 0.00016 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin Presenilin PF01080.17 OWF35967.1 - 0.42 9.3 2.0 0.62 8.8 2.0 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OWF35967.1 - 0.7 9.1 2.0 1 8.5 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SMN PF06003.12 OWF35967.1 - 4.2 6.5 13.2 1.8 7.7 4.7 2.6 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) DUF4518 PF15008.6 OWF35967.1 - 4.6 6.3 6.5 11 5.1 6.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DUF445 PF04286.12 OWF35968.1 - 8.8e-05 22.5 6.1 0.00016 21.7 6.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF4795 PF16043.5 OWF35968.1 - 2.3 7.8 5.9 0.69 9.5 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) SAC3 PF12209.8 OWF35968.1 - 2.6 8.3 6.8 17 5.7 0.1 3.4 2 1 1 3 3 3 0 Leucine permease transcriptional regulator helical domain 7tm_1 PF00001.21 OWF35969.1 - 3.1e-15 56.2 17.6 3.5e-15 56.0 17.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF35969.1 - 5.1e-06 26.3 22.5 7.6e-06 25.7 22.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF35969.1 - 0.00012 22.0 7.0 0.00012 22.0 7.0 1.6 1 1 1 2 2 2 1 Olfactory receptor Pex24p PF06398.11 OWF35969.1 - 0.15 11.0 2.3 0.3 10.0 2.3 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ABC_membrane PF00664.23 OWF35970.1 - 1.2e-80 271.1 26.8 4.7e-47 160.9 14.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF35970.1 - 7.3e-52 175.5 2.9 1.1e-29 103.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OWF35970.1 - 1.2e-11 44.5 1.7 0.00026 20.5 0.0 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OWF35970.1 - 2.5e-06 28.0 0.3 0.031 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OWF35970.1 - 3.7e-06 27.0 0.8 0.074 13.1 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF35970.1 - 0.00031 20.7 1.3 0.088 12.7 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OWF35970.1 - 0.00082 19.1 2.9 0.56 10.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OWF35970.1 - 0.0015 17.8 1.6 0.27 10.5 0.2 2.4 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.17 OWF35970.1 - 0.0021 18.2 11.2 0.095 12.8 0.3 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain NB-ARC PF00931.22 OWF35970.1 - 0.012 14.8 2.1 0.19 10.9 0.3 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 OWF35970.1 - 0.036 13.6 1.0 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 OWF35970.1 - 0.051 13.1 0.1 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TMEM18 PF14770.6 OWF35970.1 - 0.054 13.5 0.9 0.25 11.3 0.9 2.2 1 0 0 1 1 1 0 Transmembrane protein 18 AAA_24 PF13479.6 OWF35970.1 - 0.056 13.2 0.0 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OWF35970.1 - 0.067 13.4 0.8 12 6.2 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OWF35970.1 - 0.088 13.1 2.8 9.6 6.5 0.2 3.3 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 OWF35970.1 - 0.11 11.6 1.1 14 4.8 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OWF35970.1 - 0.14 12.5 0.2 10 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF3323 PF11796.8 OWF35970.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) AAA_23 PF13476.6 OWF35970.1 - 0.19 12.2 5.9 11 6.5 0.1 3.9 3 1 1 4 4 3 0 AAA domain AAA_30 PF13604.6 OWF35970.1 - 0.24 11.1 2.2 9.7 5.9 0.4 2.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF35970.1 - 0.34 10.8 1.8 1.7 8.6 0.1 2.7 3 0 0 3 3 3 0 NACHT domain AAA_21 PF13304.6 OWF35970.1 - 0.35 10.6 2.9 8.9 6.0 0.0 3.2 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AIG1 PF04548.16 OWF35970.1 - 0.66 9.3 3.9 1.8 7.9 0.1 2.6 3 0 0 3 3 3 0 AIG1 family Dynamin_N PF00350.23 OWF35970.1 - 1.8 8.6 11.4 0.11 12.6 1.0 2.9 3 0 0 3 3 3 0 Dynamin family TPH PF13868.6 OWF35971.1 - 2.1e-85 286.3 124.9 2.1e-85 286.3 124.9 2.9 2 1 1 3 3 3 1 Trichohyalin-plectin-homology domain TGS PF02824.21 OWF35972.1 - 3.2e-07 30.3 0.0 6.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 OWF35972.1 - 0.0024 17.9 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SUIM_assoc PF16619.5 OWF35972.1 - 0.15 12.2 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_7 PF03492.15 OWF35973.1 - 1.4e-30 106.7 0.1 1.7e-30 106.4 0.1 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase LpxK PF02606.14 OWF35973.1 - 0.0051 16.0 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Galactosyl_T PF01762.21 OWF35974.1 - 7e-36 123.9 0.1 9.3e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase zf-B_box PF00643.24 OWF35975.1 - 3e-05 24.1 2.8 5.6e-05 23.2 2.8 1.4 1 0 0 1 1 1 1 B-box zinc finger NigD_N PF12667.7 OWF35975.1 - 0.0073 16.4 0.1 0.018 15.2 0.1 1.6 1 0 0 1 1 1 1 NigD-like N-terminal OB domain zf-UBR PF02207.20 OWF35975.1 - 0.017 15.3 1.6 0.053 13.7 1.6 1.9 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Cu-oxidase_4 PF02578.15 OWF35976.1 - 1.1e-05 25.2 4.5 2.7 7.5 0.0 4.9 4 2 2 6 6 6 3 Multi-copper polyphenol oxidoreductase laccase LPD28 PF18843.1 OWF35976.1 - 0.00094 18.8 0.5 26 4.5 0.0 4.3 2 1 1 4 4 4 2 Large polyvalent protein associated domain 28 Prot_inhib_II PF02428.15 OWF35976.1 - 0.06 13.8 1.8 15 6.1 0.0 3.9 4 1 2 6 6 6 0 Potato type II proteinase inhibitor family DUF2475 PF10629.9 OWF35976.1 - 0.078 13.2 0.1 38 4.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2475) Ig_3 PF13927.6 OWF35977.1 - 1.6e-43 147.1 1.7 1.3e-11 44.9 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 OWF35977.1 - 1.1e-38 131.2 0.1 4.7e-12 45.8 0.0 5.5 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF35977.1 - 2.8e-36 123.7 2.2 1.3e-08 35.1 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 OWF35977.1 - 7.5e-30 102.9 1.5 1.1e-07 31.9 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 OWF35977.1 - 4.3e-20 71.8 1.7 6.2e-09 36.1 0.1 3.0 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 OWF35977.1 - 3.9e-13 49.5 13.8 0.0088 16.2 0.0 8.8 6 4 3 9 9 8 3 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF35977.1 - 4.2e-06 26.9 0.0 1.1 9.6 0.0 4.5 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 OWF35977.1 - 9.2e-06 25.6 0.1 0.34 11.0 0.0 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 OWF35977.1 - 2.6e-05 23.7 0.7 0.7 9.5 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin domain Y_Y_Y PF07495.13 OWF35977.1 - 0.00016 21.6 0.5 0.00046 20.1 0.5 1.8 1 0 0 1 1 1 1 Y_Y_Y domain Herpes_gE PF02480.16 OWF35977.1 - 0.0066 15.3 0.0 4.4 5.9 0.0 3.1 3 1 1 4 4 4 2 Alphaherpesvirus glycoprotein E Interfer-bind PF09294.10 OWF35977.1 - 0.011 16.0 0.5 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III EphA2_TM PF14575.6 OWF35977.1 - 0.051 14.4 5.8 0.16 12.8 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Izumo-Ig PF16706.5 OWF35977.1 - 0.055 13.5 0.0 17 5.5 0.0 3.6 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain 7tm_7 PF08395.12 OWF35977.1 - 0.066 12.4 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor SIT PF15330.6 OWF35977.1 - 0.076 13.5 0.8 0.21 12.1 0.1 2.2 2 0 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT MLANA PF14991.6 OWF35977.1 - 0.14 12.5 0.6 0.4 11.0 0.0 2.0 2 0 0 2 2 1 0 Protein melan-A TNFR_16_TM PF18422.1 OWF35977.1 - 0.72 9.9 2.0 1.6 8.8 2.0 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain YL1 PF05764.13 OWF35977.1 - 2.8 8.0 13.9 0.25 11.4 6.6 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Rrn6 PF10214.9 OWF35977.1 - 3.5 6.0 11.8 0.71 8.3 3.2 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor HEAT_2 PF13646.6 OWF35979.1 - 4.2e-39 132.8 6.4 7.6e-13 48.7 0.0 7.9 2 2 8 10 10 10 8 HEAT repeats HEAT PF02985.22 OWF35979.1 - 1.9e-38 127.2 25.3 0.0022 18.1 0.1 13.7 14 0 0 14 14 14 11 HEAT repeat Vac14_Fab1_bd PF12755.7 OWF35979.1 - 3e-11 43.8 2.2 0.14 12.7 0.0 7.3 3 2 4 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OWF35979.1 - 2.4e-08 34.3 6.9 0.49 11.0 0.0 7.9 6 1 4 10 10 9 2 HEAT-like repeat CLASP_N PF12348.8 OWF35979.1 - 4e-08 33.1 1.5 0.35 10.4 0.0 4.7 3 2 2 5 5 5 3 CLASP N terminal Cnd1 PF12717.7 OWF35979.1 - 8.2e-08 32.5 7.9 0.2 11.7 0.4 5.1 3 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OWF35979.1 - 2.7e-06 26.2 5.7 0.00028 19.6 2.5 3.5 1 1 1 2 2 2 1 Adaptin N terminal region TAF6_C PF07571.13 OWF35979.1 - 0.00068 19.9 0.1 4.9 7.6 0.0 4.7 4 1 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain M11L PF11099.8 OWF35979.1 - 0.027 14.8 2.1 0.13 12.5 0.0 2.8 2 1 2 4 4 4 0 Apoptosis regulator M11L like mRNA_stabil PF13929.6 OWF35979.1 - 0.12 11.3 1.5 0.96 8.4 0.0 3.0 3 1 1 4 4 4 0 mRNA stabilisation Imm30 PF15565.6 OWF35979.1 - 0.17 12.0 0.2 8.4 6.5 0.1 3.3 2 2 0 2 2 2 0 Immunity protein 30 RNA_pol_L_2 PF13656.6 OWF35981.1 - 5.3e-31 106.2 0.0 7.8e-31 105.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OWF35981.1 - 2.4e-15 55.7 0.0 3.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-B_box PF00643.24 OWF35983.1 - 2.3e-10 40.5 6.0 2.3e-10 40.5 6.0 2.7 4 0 0 4 4 3 1 B-box zinc finger zf-RING_UBOX PF13445.6 OWF35983.1 - 1.3e-07 31.5 5.1 1.3e-07 31.5 5.1 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF35983.1 - 9e-06 25.9 7.6 9e-06 25.9 7.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OWF35983.1 - 1.5e-05 24.7 8.2 1.5e-05 24.7 8.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF35983.1 - 6.8e-05 22.7 7.1 6.8e-05 22.7 7.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF35983.1 - 0.00036 20.3 4.6 0.00036 20.3 4.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF35983.1 - 0.006 16.7 6.7 0.006 16.7 6.7 3.3 3 2 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OWF35983.1 - 0.019 14.7 6.6 0.019 14.7 6.6 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OWF35983.1 - 0.022 14.5 5.3 0.058 13.1 5.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 OWF35983.1 - 0.035 14.2 6.6 1.5 9.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger Glyco_hydro_77 PF02446.17 OWF35983.1 - 0.2 10.5 3.8 0.27 10.0 3.2 1.5 1 1 1 2 2 2 0 4-alpha-glucanotransferase CEBP_ZZ PF16366.5 OWF35983.1 - 0.57 10.5 10.8 1.7 9.0 0.9 2.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-4CXXC_R1 PF10497.9 OWF35983.1 - 1.2 9.4 14.2 0.061 13.5 5.1 2.6 1 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 NHL PF01436.21 OWF35984.1 - 1.2e-34 116.6 16.0 7.4e-10 38.4 0.1 6.4 6 0 0 6 6 6 5 NHL repeat zf-B_box PF00643.24 OWF35984.1 - 7.8e-09 35.5 7.6 7.8e-09 35.5 7.6 4.0 3 1 0 3 3 2 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF35984.1 - 7.9e-08 32.2 9.1 7.9e-08 32.2 9.1 3.2 4 0 0 4 4 2 1 RING-type zinc-finger DUF5128 PF17170.4 OWF35984.1 - 7.7e-06 25.3 12.2 7.1e-05 22.1 0.3 3.7 4 1 0 4 4 4 2 6-bladed beta-propeller zf-C3HC4 PF00097.25 OWF35984.1 - 1.8e-05 24.5 12.4 1.8e-05 24.5 12.4 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF35984.1 - 4.3e-05 23.2 0.2 0.33 10.5 0.0 3.5 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-RING_5 PF14634.6 OWF35984.1 - 9.2e-05 22.3 12.9 9.2e-05 22.3 12.9 3.8 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF35984.1 - 0.0019 18.3 11.7 0.0019 18.3 11.7 3.2 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING Fib_alpha PF08702.10 OWF35984.1 - 0.0051 17.0 3.2 0.0051 17.0 3.2 1.9 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family zf-C3HC4_2 PF13923.6 OWF35984.1 - 0.014 15.3 10.9 0.014 15.3 10.9 3.6 3 1 0 3 3 1 0 Zinc finger, C3HC4 type (RING finger) RRP7 PF12923.7 OWF35984.1 - 0.047 13.8 2.0 0.098 12.8 2.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RuvB_C PF05491.13 OWF35984.1 - 0.13 12.2 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain DUF5082 PF16888.5 OWF35984.1 - 0.23 11.7 3.5 0.48 10.7 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 OWF35984.1 - 0.42 9.9 2.6 0.65 9.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MbeD_MobD PF04899.12 OWF35984.1 - 0.7 10.1 3.9 0.81 9.8 1.9 2.0 2 0 0 2 2 2 0 MbeD/MobD like CHU_C PF13585.6 OWF35984.1 - 4.3 7.5 13.2 7 6.8 0.0 5.0 6 0 0 6 6 5 0 C-terminal domain of CHU protein family Maf PF02545.14 OWF35985.1 - 3.3e-52 176.7 0.0 4e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein UPF0231 PF06062.11 OWF35985.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) SSF PF00474.17 OWF35986.1 - 3e-09 36.3 30.7 1.5e-08 34.0 19.1 2.8 3 0 0 3 3 3 2 Sodium:solute symporter family DUF4574 PF15141.6 OWF35986.1 - 0.095 12.6 0.1 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Band_7_1 PF13421.6 OWF35987.1 - 0.063 13.0 3.8 4.7 6.9 0.1 3.7 1 1 3 4 4 4 0 SPFH domain-Band 7 family ELFV_dehydrog PF00208.21 OWF35987.1 - 0.15 11.8 0.1 9.3 5.9 0.0 2.8 1 1 2 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PHR PF08005.12 OWF35988.1 - 1.3e-88 295.4 0.4 3.7e-43 147.8 0.0 3.2 3 0 0 3 3 3 2 PHR domain RCC1 PF00415.18 OWF35988.1 - 4.7e-23 81.5 14.2 1.2e-11 45.1 0.5 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF35988.1 - 6.3e-18 64.1 16.2 1.8e-08 33.9 0.8 5.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat SH3_3 PF08239.11 OWF35988.1 - 8.4e-13 48.4 0.0 7.4e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 Bacterial SH3 domain Filamin PF00630.19 OWF35988.1 - 0.0003 21.6 0.0 0.0014 19.4 0.0 2.2 1 0 0 1 1 1 1 Filamin/ABP280 repeat DUF3391 PF11871.8 OWF35988.1 - 1.1 9.8 6.1 11 6.6 0.3 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) MFS_1_like PF12832.7 OWF35989.1 - 9.4e-86 288.1 20.7 1.2e-85 287.7 20.7 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OWF35989.1 - 2e-17 63.2 53.1 5.5e-09 35.4 5.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OWF35989.1 - 6.8e-16 58.2 29.0 4.9e-13 48.8 22.1 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 OWF35989.1 - 7.9e-09 34.8 35.3 0.00016 20.6 21.9 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter UPF0220 PF05255.11 OWF35989.1 - 0.04 13.5 4.6 0.081 12.5 4.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) P5-ATPase PF12409.8 OWF35989.1 - 1.1 9.4 4.1 0.3 11.2 0.3 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter Otopetrin PF03189.13 OWF35990.1 - 4.5e-24 85.1 5.9 4.5e-24 85.1 5.9 2.6 2 1 1 3 3 3 2 Otopetrin SLD5_C PF16922.5 OWF35991.1 - 1.3e-14 54.1 0.0 3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OWF35991.1 - 5.7e-05 23.5 2.4 0.00013 22.4 1.9 1.9 1 1 0 1 1 1 1 GINS complex protein DUF61 PF01886.16 OWF35991.1 - 0.031 14.3 0.2 0.97 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF61 CBM_21 PF03370.13 OWF35992.1 - 6.7e-29 100.3 1.2 1.1e-28 99.7 1.2 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OWF35992.1 - 2.2e-13 50.6 1.0 4e-13 49.8 1.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) PocR PF10114.9 OWF35992.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR CCDC106 PF15794.5 OWF35992.1 - 0.29 10.8 0.8 0.47 10.1 0.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PIG-S PF10510.9 OWF35994.1 - 5.5e-129 431.3 0.2 6.6e-129 431.0 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein NUC173 PF08161.12 OWF35995.1 - 4.9e-68 228.8 1.0 5.7e-63 212.3 0.0 4.1 6 0 0 6 6 6 2 NUC173 domain FemAB PF02388.16 OWF35995.1 - 0.23 10.3 6.2 0.29 10.0 4.6 1.8 2 0 0 2 2 2 0 FemAB family p450 PF00067.22 OWF35997.1 - 1.3e-92 311.0 0.0 6.6e-92 308.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Ephrin PF00812.17 OWF35998.1 - 9.5e-35 119.6 0.1 1.4e-34 119.1 0.1 1.2 1 0 0 1 1 1 1 Ephrin Mucin PF01456.17 OWF35998.1 - 0.8 9.7 21.5 1.4 9.0 21.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 OWF35998.1 - 1.9 6.3 5.6 2.5 6.0 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MGC-24 PF05283.11 OWF35998.1 - 5.7 7.4 11.8 11 6.5 11.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Peptidase_C1 PF00112.23 OWF35999.1 - 8.7e-82 274.4 3.0 1.3e-81 273.9 3.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF35999.1 - 5.9e-15 55.4 3.5 1.1e-14 54.6 3.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF35999.1 - 2.3e-05 23.4 0.6 0.036 12.8 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family F-box PF00646.33 OWF36000.1 - 1.6e-06 27.9 2.4 4.7e-06 26.3 0.3 2.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OWF36000.1 - 4.8e-05 23.2 0.7 0.00019 21.3 0.2 2.3 3 0 0 3 3 3 1 F-box-like TPR_2 PF07719.17 OWF36001.1 - 2.7e-35 117.6 8.1 4.7e-05 23.2 0.0 12.5 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF36001.1 - 1.2e-33 113.5 21.6 1.5e-06 27.8 0.0 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_12 PF13424.6 OWF36001.1 - 2.7e-29 101.3 7.2 6.6e-08 32.7 0.0 9.2 6 2 4 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.6 OWF36001.1 - 7.6e-24 82.7 8.4 0.031 14.9 0.0 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF36001.1 - 3.8e-22 76.6 3.3 0.00086 19.2 0.0 10.6 13 0 0 13 13 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF36001.1 - 6.6e-22 77.9 0.0 2.7e-08 34.3 0.0 6.2 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF36001.1 - 1.6e-21 74.7 24.6 0.16 12.2 0.0 12.4 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 OWF36001.1 - 8.6e-19 67.8 0.1 0.00033 21.1 0.0 6.6 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF36001.1 - 2.9e-15 55.7 0.9 4.3e-06 26.3 0.0 6.2 6 1 0 6 6 6 2 TPR repeat ANAPC3 PF12895.7 OWF36001.1 - 1.5e-14 54.0 9.9 4.3e-07 30.1 0.3 5.7 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OWF36001.1 - 2.2e-14 52.9 0.0 0.15 12.9 0.0 8.0 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_21 PF09976.9 OWF36001.1 - 7.1e-09 35.7 5.1 3.1e-05 23.8 1.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 OWF36001.1 - 9.4e-09 35.3 0.0 0.018 15.2 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF36001.1 - 5e-08 32.6 5.8 0.31 11.0 0.0 7.3 9 0 0 9 9 9 2 Tetratricopeptide repeat DUF2225 PF09986.9 OWF36001.1 - 1.6e-06 28.0 5.7 0.0015 18.3 0.3 4.4 2 2 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 OWF36001.1 - 1.8e-06 27.9 5.0 0.67 10.5 0.1 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF36001.1 - 3.4e-06 26.7 0.1 0.18 11.1 0.0 4.1 3 1 3 6 6 6 2 MalT-like TPR region Coatomer_E PF04733.14 OWF36001.1 - 2e-05 24.2 1.8 0.0012 18.4 0.0 3.7 3 2 1 4 4 4 1 Coatomer epsilon subunit DUF3808 PF10300.9 OWF36001.1 - 9.9e-05 21.2 1.9 0.00085 18.2 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) TPR_15 PF13429.6 OWF36001.1 - 0.00012 21.4 0.9 0.3 10.3 0.0 4.2 2 2 3 5 5 5 1 Tetratricopeptide repeat Sel1 PF08238.12 OWF36001.1 - 0.00099 19.7 2.6 86 4.0 0.0 5.7 5 0 0 5 5 5 0 Sel1 repeat MIT PF04212.18 OWF36001.1 - 0.0018 18.3 9.8 1 9.5 0.1 6.4 7 0 0 7 7 6 1 MIT (microtubule interacting and transport) domain DUF4810 PF16068.5 OWF36001.1 - 0.0058 17.1 0.1 85 3.8 0.0 5.5 5 1 1 6 6 5 0 Domain of unknown function (DUF4810) TPR_20 PF14561.6 OWF36001.1 - 0.0082 16.4 1.8 19 5.7 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 OWF36001.1 - 0.011 15.9 5.0 3.3 8.2 0.0 5.9 8 0 0 8 8 5 0 PPR repeat HrpB1_HrpK PF09613.10 OWF36001.1 - 0.054 13.1 0.0 11 5.7 0.0 3.4 3 1 1 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF5568 PF17724.1 OWF36001.1 - 5.2 6.8 11.3 1 9.1 1.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5568) RA PF00788.23 OWF36002.1 - 8.5e-35 119.3 0.0 3e-16 59.8 0.0 2.9 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 OWF36002.1 - 1.9e-34 118.1 0.5 4.8e-34 116.8 0.5 1.8 1 0 0 1 1 1 1 DIL domain PDZ PF00595.24 OWF36002.1 - 8.5e-16 58.1 0.6 2.1e-15 56.8 0.6 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF36002.1 - 8.9e-08 31.9 0.1 2.1e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF36002.1 - 1.3e-06 28.6 0.1 6.2e-06 26.4 0.1 2.2 1 0 0 1 1 1 1 PDZ domain FHA PF00498.26 OWF36002.1 - 4.5e-06 26.9 0.0 1.4e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain Ank_2 PF12796.7 OWF36003.1 - 0.00059 20.4 4.6 2.1 9.0 1.4 4.0 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF36003.1 - 0.17 12.6 0.9 36 5.4 0.0 4.1 5 0 0 5 5 5 0 Ankyrin repeat CAP_GLY PF01302.25 OWF36004.1 - 1.8e-18 66.3 1.0 6.1e-18 64.6 1.0 1.9 1 0 0 1 1 1 1 CAP-Gly domain ZapB PF06005.12 OWF36004.1 - 0.0077 16.7 0.4 0.0077 16.7 0.4 5.5 5 1 0 5 5 5 1 Cell division protein ZapB GUB_WAK_bind PF13947.6 OWF36004.1 - 0.018 15.8 0.0 0.077 13.7 0.0 2.1 1 0 0 1 1 1 0 Wall-associated receptor kinase galacturonan-binding WD40_alt PF14077.6 OWF36004.1 - 0.11 12.4 1.9 0.73 9.7 0.0 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif YabA PF06156.13 OWF36004.1 - 0.13 12.9 22.3 1.4 9.6 1.0 4.8 3 1 0 3 3 3 0 Initiation control protein YabA GIT_CC PF16559.5 OWF36004.1 - 2.9 7.8 11.5 0.71 9.8 0.8 4.0 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_TATA_bd PF12325.8 OWF36004.1 - 3.3 8.0 23.5 3.2 8.0 0.6 4.7 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 OWF36004.1 - 7.2 6.7 26.6 0.01 15.9 6.7 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 OWF36004.1 - 8.5 6.6 26.3 0.51 10.5 3.4 5.1 4 1 0 5 5 5 0 bZIP transcription factor RMI1_C PF16099.5 OWF36005.1 - 4e-06 26.7 5.6 0.13 12.1 0.1 5.1 1 1 5 6 6 6 2 Recq-mediated genome instability protein 1, C-terminal OB-fold ABM PF03992.16 OWF36005.1 - 1.7e-05 24.8 11.1 7.4 6.8 0.3 6.6 1 1 4 5 5 5 2 Antibiotic biosynthesis monooxygenase DDE_Tnp_IS240 PF13610.6 OWF36005.1 - 0.0018 18.5 1.6 2.3 8.5 0.1 3.5 1 1 2 3 3 3 1 DDE domain HypF_C PF17788.1 OWF36005.1 - 0.008 16.8 3.1 1e+02 3.7 0.1 5.0 1 1 3 5 5 5 0 HypF Kae1-like domain Com_YlbF PF06133.11 OWF36005.1 - 0.0081 16.7 18.7 0.29 11.7 8.0 2.9 1 1 1 2 2 2 2 Control of competence regulator ComK, YlbF/YmcA 17kDa_Anti_2 PF16998.5 OWF36005.1 - 0.1 12.6 0.8 6.1 6.8 0.0 3.2 1 1 1 4 4 4 0 17 kDa outer membrane surface antigen Strumpellin PF10266.9 OWF36005.1 - 0.24 9.0 4.5 1.4 6.5 0.1 2.1 1 1 1 2 2 2 0 Hereditary spastic paraplegia protein strumpellin OmpH PF03938.14 OWF36005.1 - 1.8 8.9 11.6 4.3e+02 1.2 11.6 3.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SCVP PF17619.2 OWF36005.1 - 2 9.3 4.4 14 6.6 3.1 2.9 1 1 1 2 2 2 0 Secreted clade V proteins Ldl_recept_a PF00057.18 OWF36006.1 - 9.5e-63 208.1 117.9 8.4e-14 51.5 11.4 7.3 6 0 0 6 6 6 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 OWF36006.1 - 1.3e-27 96.0 6.7 2.5e-07 31.0 0.1 8.9 9 0 0 9 9 9 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 OWF36006.1 - 2.3e-11 43.7 49.9 7.8e-06 26.1 5.3 7.6 8 3 0 8 8 8 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF36006.1 - 1.2e-06 28.3 30.7 0.00036 20.4 1.6 5.5 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF36006.1 - 3.2e-05 24.0 10.2 3.2e-05 24.0 10.2 10.5 5 2 3 8 8 8 1 Calcium-binding EGF domain SGL PF08450.12 OWF36006.1 - 0.0091 15.6 1.2 0.37 10.3 0.2 4.0 3 1 0 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region SPATA3 PF15662.5 OWF36009.1 - 0.58 10.8 5.1 0.57 10.8 5.1 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Hyccin PF09790.9 OWF36010.1 - 1.2e-102 343.3 0.5 3.2e-102 341.9 0.0 1.8 2 0 0 2 2 2 1 Hyccin Rpr2 PF04032.16 OWF36010.1 - 0.1 12.9 0.5 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PAS_6 PF08348.11 OWF36010.1 - 0.2 11.5 1.2 0.66 9.9 1.2 1.8 1 0 0 1 1 1 0 YheO-like PAS domain EF-hand_7 PF13499.6 OWF36011.1 - 6e-30 103.5 0.2 1.2e-14 54.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF36011.1 - 3.4e-29 98.2 11.0 1.2e-07 30.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF36011.1 - 4.4e-22 76.1 5.2 1.7e-07 30.6 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF36011.1 - 1e-19 70.1 8.1 1.8e-09 37.3 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF36011.1 - 1.8e-19 68.2 8.7 1e-05 24.8 0.1 4.3 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 OWF36011.1 - 4.2e-06 27.0 0.1 0.1 12.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF36011.1 - 1.3e-05 25.1 2.5 0.23 11.4 0.2 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF36011.1 - 1.4e-05 25.0 0.0 0.028 14.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 OWF36011.1 - 7.7e-05 22.7 0.5 0.0083 16.1 0.2 2.4 1 1 1 2 2 2 1 Caleosin related protein EF-hand_9 PF14658.6 OWF36011.1 - 0.0017 18.6 0.1 0.029 14.7 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 OWF36011.1 - 0.0053 16.9 3.9 4.3 7.6 0.2 3.3 2 2 1 3 3 3 2 Dockerin type I domain CUB PF00431.20 OWF36013.1 - 2.5e-14 53.5 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.20 OWF36013.1 - 0.0018 18.0 0.4 0.0024 17.6 0.4 1.2 1 0 0 1 1 1 1 CUB-like domain DUF4358 PF14270.6 OWF36014.1 - 2.2 8.6 4.2 7.9 6.8 0.6 2.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4358) WD40 PF00400.32 OWF36015.1 - 5.1e-51 169.5 18.7 1.7e-10 41.3 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OWF36015.1 - 1.4e-41 141.8 5.8 2.7e-41 140.8 5.8 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 OWF36015.1 - 4.6e-12 46.1 0.0 6e-05 23.3 0.0 5.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF36015.1 - 7.1e-05 21.9 0.0 1.9 7.3 0.0 4.2 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OWF36015.1 - 7.7e-05 21.5 0.2 0.093 11.4 0.0 2.6 2 0 0 2 2 2 2 Nucleoporin Nup120/160 LisH PF08513.11 OWF36015.1 - 0.0021 18.0 0.0 0.075 13.0 0.0 2.5 2 0 0 2 2 2 1 LisH LisH_TPL PF17814.1 OWF36015.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain HEAT PF02985.22 OWF36016.1 - 3.8e-17 60.9 10.5 0.002 18.2 0.0 7.4 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 OWF36016.1 - 4.1e-09 36.7 0.0 0.00034 20.9 0.0 4.7 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 OWF36016.1 - 6.3e-08 33.0 2.1 0.00072 20.0 0.3 4.1 4 1 1 5 5 5 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OWF36016.1 - 9.3e-08 32.6 0.7 0.028 15.0 0.0 4.6 4 1 2 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OWF36016.1 - 1e-05 25.6 0.1 0.6 10.1 0.0 4.9 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OWF36016.1 - 7.1e-05 22.5 0.0 5.1 6.6 0.1 3.8 3 2 0 3 3 3 3 CLASP N terminal IFRD PF05004.13 OWF36016.1 - 0.00049 19.3 0.1 0.15 11.2 0.1 3.6 2 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) FAD_binding_4 PF01565.23 OWF36016.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain XRN_M PF17846.1 OWF36017.1 - 6e-160 533.0 0.0 8.7e-160 532.5 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 OWF36017.1 - 6.5e-101 336.8 0.0 9.1e-101 336.3 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_4 PF14392.6 OWF36017.1 - 0.072 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Homeodomain PF00046.29 OWF36018.1 - 2.6e-20 72.0 4.5 5.7e-20 70.9 4.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF36018.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain SPX PF03105.19 OWF36018.1 - 4.5 7.1 16.1 7 6.4 16.1 1.4 1 0 0 1 1 1 0 SPX domain 7tm_1 PF00001.21 OWF36019.1 - 8.7e-09 35.1 9.7 8.7e-09 35.1 9.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 OWF36019.1 - 2.2e-06 27.6 13.3 3.6e-06 26.9 13.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3 PF11710.8 OWF36020.1 - 2.1e-06 27.7 8.9 2.1e-06 27.7 8.9 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 PHD PF00628.29 OWF36022.1 - 0.00028 20.7 7.6 0.00028 20.7 7.6 1.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 OWF36022.1 - 0.0012 19.0 0.9 0.0026 17.9 0.9 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OWF36022.1 - 0.0016 18.7 1.0 0.0034 17.6 1.0 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain HECA PF15353.6 OWF36022.1 - 0.003 17.8 0.9 0.0063 16.7 0.9 1.6 1 0 0 1 1 1 1 Headcase protein family homologue Galactosyl_T PF01762.21 OWF36023.1 - 6.1e-47 160.0 0.9 7.2e-47 159.7 0.9 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF36023.1 - 0.00012 21.7 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Fringe-like Focal_AT PF03623.13 OWF36023.1 - 0.037 14.0 0.2 7.1 6.6 0.1 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region MIOX PF05153.15 OWF36024.1 - 6.7e-111 369.8 6.9 7.9e-111 369.6 6.9 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 OWF36024.1 - 0.09 13.0 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 HD domain Bax1-I PF01027.20 OWF36025.1 - 2e-44 151.9 20.1 2.3e-44 151.7 20.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Tubulin PF00091.25 OWF36026.1 - 1.7e-44 152.4 0.0 2.8e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 OWF36026.1 - 0.038 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Sulfotransfer_1 PF00685.27 OWF36027.1 - 3.3e-46 157.9 4.2 3.7e-46 157.8 4.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36027.1 - 7e-08 33.1 0.0 1.1e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family AAA_25 PF13481.6 OWF36027.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_2 PF13472.6 OWF36028.1 - 0.00038 20.9 0.0 0.00045 20.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sulfotransfer_1 PF00685.27 OWF36029.1 - 1.3e-51 175.7 3.4 4.3e-50 170.7 3.4 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36029.1 - 2.3e-07 31.4 0.0 1.1e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Methyltransf_15 PF09445.10 OWF36029.1 - 0.063 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AAA_25 PF13481.6 OWF36029.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sulfotransfer_1 PF00685.27 OWF36030.1 - 1.1e-51 175.8 2.8 6.6e-50 170.1 2.8 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36030.1 - 6.8e-07 29.9 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family MREG PF15812.5 OWF36030.1 - 0.054 13.8 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 Melanoregulin Sulfotransfer_1 PF00685.27 OWF36031.1 - 5.3e-97 324.5 16.9 7.7e-48 163.3 4.2 3.8 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36031.1 - 3.6e-15 56.9 0.0 3.4e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 Sulfotransferase family MREG PF15812.5 OWF36031.1 - 0.0014 18.9 0.0 0.36 11.1 0.0 2.3 2 0 0 2 2 2 1 Melanoregulin DUF1609 PF07753.11 OWF36031.1 - 0.0074 15.9 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1609) Nup54 PF13874.6 OWF36031.1 - 0.056 13.5 0.2 0.87 9.7 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IFT81_CH PF18383.1 OWF36031.1 - 0.11 12.7 0.4 15 5.9 0.0 3.0 4 0 0 4 4 4 0 Intraflagellar transport 81 calponin homology domain PBP_GOBP PF01395.22 OWF36031.1 - 0.14 12.3 7.2 1.5 9.0 1.1 2.4 2 0 0 2 2 2 0 PBP/GOBP family AAA_25 PF13481.6 OWF36031.1 - 0.18 11.3 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3899 PF13038.6 OWF36031.1 - 0.35 11.4 2.9 0.54 10.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Sulfotransfer_1 PF00685.27 OWF36032.1 - 6.6e-46 156.9 2.5 1.5e-44 152.5 2.5 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36032.1 - 0.00057 20.3 0.0 0.02 15.3 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family SAP PF02037.27 OWF36033.1 - 2.3e-10 40.0 0.1 2.8e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 SAP domain FMO-like PF00743.19 OWF36034.1 - 4.4e-44 150.8 0.0 1.3e-27 96.5 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF36034.1 - 2e-14 53.6 0.0 7.1e-11 41.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF36034.1 - 3.7e-11 42.8 0.0 2.6e-09 36.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OWF36034.1 - 2e-08 33.8 0.0 1.9e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF36034.1 - 8.3e-06 25.9 0.0 0.22 11.5 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF36034.1 - 0.0008 19.6 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-C4 PF00105.18 OWF36036.1 - 1.6e-31 108.5 16.3 3.7e-31 107.4 16.3 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF36036.1 - 2.5e-24 86.0 0.4 5e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor MinE PF03776.14 OWF36036.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE zf-C4 PF00105.18 OWF36037.1 - 2.5e-32 111.1 15.8 4.3e-32 110.4 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF36037.1 - 5e-29 101.4 0.6 1e-28 100.4 0.6 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MinE PF03776.14 OWF36037.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE SIT PF15330.6 OWF36038.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Spaetzle PF16077.5 OWF36038.1 - 9 6.9 10.9 1.2 9.7 5.2 2.4 3 1 0 3 3 3 0 Spaetzle DUF5587 PF17825.1 OWF36039.1 - 3e-34 117.7 2.1 3e-34 117.7 2.1 2.4 3 0 0 3 3 3 2 Family of unknown function (DUF5587) CLP_protease PF00574.23 OWF36040.1 - 2.4e-64 216.6 0.3 3.2e-64 216.2 0.3 1.1 1 0 0 1 1 1 1 Clp protease TPR_12 PF13424.6 OWF36041.1 - 1.9e-10 40.9 0.5 0.0001 22.5 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat CARD PF00619.21 OWF36041.1 - 4.4e-10 39.5 0.2 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Caspase recruitment domain TPR_10 PF13374.6 OWF36041.1 - 8.1e-05 22.4 0.1 2 8.4 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat C1q PF00386.21 OWF36042.1 - 1.4e-17 64.1 0.0 1.9e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 OWF36043.1 - 2e-18 66.8 0.4 3e-18 66.3 0.4 1.3 1 0 0 1 1 1 1 C1q domain OPT PF03169.15 OWF36043.1 - 0.047 12.3 0.1 0.055 12.1 0.1 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein C1q PF00386.21 OWF36044.1 - 6.2e-23 81.4 0.0 9.4e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 C1q domain ATG16 PF08614.11 OWF36044.1 - 0.00053 20.3 2.5 0.0008 19.7 2.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 OWF36044.1 - 0.0036 17.9 0.8 0.014 16.0 1.5 1.6 2 0 0 2 2 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4795 PF16043.5 OWF36044.1 - 0.011 15.3 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 OWF36044.1 - 0.017 15.2 0.9 0.024 14.6 0.9 1.3 1 0 0 1 1 1 0 Laminin Domain II Tropomyosin_1 PF12718.7 OWF36044.1 - 0.021 15.0 1.0 0.031 14.4 1.0 1.2 1 0 0 1 1 1 0 Tropomyosin like ADIP PF11559.8 OWF36044.1 - 0.024 14.7 2.7 0.12 12.4 3.7 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MetOD2 PF18548.1 OWF36044.1 - 0.048 13.8 0.3 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 Metanogen output domain 2 Atg14 PF10186.9 OWF36044.1 - 0.058 12.5 1.6 0.083 12.0 1.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FTO_CTD PF12934.7 OWF36044.1 - 0.059 13.1 0.6 0.087 12.6 0.6 1.2 1 0 0 1 1 1 0 FTO C-terminal domain DUF641 PF04859.12 OWF36044.1 - 0.06 13.7 1.3 0.1 12.9 1.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) AKNA PF12443.8 OWF36044.1 - 0.065 13.9 0.3 7.2 7.3 0.4 2.4 2 1 0 2 2 2 0 AT-hook-containing transcription factor Snf7 PF03357.21 OWF36044.1 - 0.074 12.7 3.1 0.11 12.1 3.1 1.1 1 0 0 1 1 1 0 Snf7 Med9 PF07544.13 OWF36044.1 - 0.074 13.1 1.5 0.2 11.8 1.5 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Troponin PF00992.20 OWF36044.1 - 0.088 13.1 1.6 0.17 12.2 1.6 1.4 1 1 0 1 1 1 0 Troponin DUF1664 PF07889.12 OWF36044.1 - 0.16 12.0 1.5 0.28 11.2 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OWF36044.1 - 0.18 11.0 1.3 0.23 10.6 1.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein ELO PF01151.18 OWF36045.1 - 1.6e-66 224.4 21.1 2e-66 224.1 21.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CedA PF10729.9 OWF36045.1 - 0.031 14.1 0.8 0.064 13.1 0.1 1.9 2 0 0 2 2 2 0 Cell division activator CedA TraB PF01963.17 OWF36046.1 - 3.5e-63 214.0 0.0 4.5e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 TraB family LSM PF01423.22 OWF36047.1 - 1.9e-16 59.5 0.0 3.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OWF36047.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Ofd1_CTDD PF10637.9 OWF36048.1 - 5.1e-39 134.2 0.0 3.8e-34 118.2 0.0 2.4 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OWF36048.1 - 1.1e-35 122.2 0.0 2.4e-27 95.5 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OWF36048.1 - 7e-18 65.3 0.0 8e-14 52.3 0.0 2.6 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily BRD4_CDT PF17105.5 OWF36048.1 - 0.85 9.3 4.6 0.32 10.6 1.6 1.9 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 FANCI_S1-cap PF14674.6 OWF36048.1 - 1.3 9.1 4.1 0.34 11.0 0.4 1.9 2 0 0 2 2 2 0 FANCI solenoid 1 cap 2OG-FeII_Oxy_3 PF13640.6 OWF36049.1 - 3.4e-15 56.7 0.1 6.2e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_1 PF00036.32 OWF36049.1 - 5.5e-06 25.6 4.2 0.033 13.7 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF36049.1 - 2.2e-05 24.0 4.5 0.027 14.4 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OWF36049.1 - 0.00066 20.1 4.0 0.00099 19.5 2.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF36049.1 - 0.053 13.0 5.1 1.4 8.5 0.7 2.6 2 0 0 2 2 2 0 EF hand Epimerase PF01370.21 OWF36050.1 - 2.7e-22 79.4 0.0 3.6e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF36050.1 - 3.2e-15 56.4 0.0 3.7e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OWF36050.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OWF36050.1 - 6.4e-08 31.9 0.0 9.6e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OWF36050.1 - 1.2e-06 27.9 0.0 6.2e-06 25.6 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 OWF36050.1 - 2.3e-05 23.7 0.0 0.00011 21.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OWF36050.1 - 0.024 14.6 0.1 0.13 12.2 0.1 2.1 1 1 0 1 1 1 0 KR domain Corona_RPol_N PF06478.13 OWF36050.1 - 0.039 13.0 0.1 0.058 12.4 0.1 1.2 1 0 0 1 1 1 0 Coronavirus RPol N-terminus HSP70 PF00012.20 OWF36052.1 - 0.0017 16.6 0.0 0.033 12.4 0.0 2.3 1 1 0 1 1 1 1 Hsp70 protein StbA PF06406.11 OWF36052.1 - 0.15 11.3 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 StbA protein Cytochrom_B561 PF03188.16 OWF36053.1 - 0.036 14.2 0.6 0.036 14.2 0.6 2.3 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 UPF0182 PF03699.13 OWF36053.1 - 0.047 11.8 0.5 0.053 11.6 0.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) CPBP PF02517.16 OWF36053.1 - 7.7 7.0 9.1 73 3.8 9.1 2.1 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease CTD PF12815.7 OWF36054.1 - 7.9e-17 61.6 23.1 0.49 11.0 0.5 11.7 5 4 1 6 6 6 5 Spt5 C-terminal nonapeptide repeat binding Spt4 IL4Ra_N PF09238.10 OWF36054.1 - 0.23 11.8 63.9 3.2 8.1 1.6 9.7 2 2 9 11 11 11 0 Interleukin-4 receptor alpha chain, N-terminal DUF2371 PF10177.9 OWF36055.1 - 1.2e-07 32.0 0.0 3.4e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) DUF3185 PF11381.8 OWF36055.1 - 0.21 11.6 0.8 0.36 10.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Trypsin PF00089.26 OWF36056.1 - 1e-47 162.8 0.4 1.2e-47 162.6 0.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF36056.1 - 2.4e-05 25.3 0.8 4e-05 24.6 0.5 1.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain Prominin PF05478.11 OWF36058.1 - 5.6e-114 381.8 14.0 1.4e-98 331.0 2.5 2.0 1 1 1 2 2 2 2 Prominin DUF2207 PF09972.9 OWF36058.1 - 1.3e-07 30.8 0.3 7.9e-05 21.6 0.0 3.0 3 0 0 3 3 3 1 Predicted membrane protein (DUF2207) Apolipoprotein PF01442.18 OWF36058.1 - 6.9e-05 22.8 9.1 0.0011 18.9 0.6 3.0 3 0 0 3 3 3 2 Apolipoprotein A1/A4/E domain AI-2E_transport PF01594.16 OWF36058.1 - 0.0023 17.2 9.6 0.9 8.6 0.0 4.2 4 0 0 4 4 4 2 AI-2E family transporter Shisa PF13908.6 OWF36058.1 - 0.003 17.8 0.4 0.041 14.1 1.5 2.3 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF1640 PF07798.11 OWF36058.1 - 0.014 15.4 7.0 0.39 10.7 1.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) DUF5082 PF16888.5 OWF36058.1 - 0.024 14.9 11.1 0.069 13.4 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) CCDC154 PF15450.6 OWF36058.1 - 0.027 13.0 3.7 0.2 10.2 0.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 Exonuc_VII_L PF02601.15 OWF36058.1 - 0.028 14.0 1.5 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit RasGAP_C PF03836.15 OWF36058.1 - 0.035 14.2 2.5 2.4 8.3 0.7 2.8 1 1 0 2 2 2 0 RasGAP C-terminus PhaP_Bmeg PF09602.10 OWF36058.1 - 0.041 13.8 10.0 0.78 9.6 1.1 3.5 3 1 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phage_holin_3_6 PF07332.11 OWF36058.1 - 0.15 12.1 0.0 0.15 12.1 0.0 4.6 3 2 1 4 4 3 0 Putative Actinobacterial Holin-X, holin superfamily III Zw10 PF06248.13 OWF36058.1 - 0.56 8.7 4.7 0.18 10.3 0.6 2.1 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF4795 PF16043.5 OWF36058.1 - 0.69 9.5 6.8 1 8.9 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) BshC PF10079.9 OWF36058.1 - 0.73 8.5 4.1 2.4 6.8 0.8 2.2 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC BLOC1_2 PF10046.9 OWF36058.1 - 2 8.8 12.5 6.5 7.1 1.4 3.9 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0139 PF03669.13 OWF36058.1 - 2.3 8.2 6.9 0.13 12.1 0.8 2.1 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0139) GerPC PF10737.9 OWF36058.1 - 2.4 8.2 8.9 1.3 9.1 1.1 2.8 3 0 0 3 3 2 0 Spore germination protein GerPC DUF1218 PF06749.12 OWF36058.1 - 2.8 8.5 15.4 0.38 11.3 2.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DUF948 PF06103.11 OWF36058.1 - 2.9 8.2 22.6 0.27 11.5 1.0 5.0 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 OWF36058.1 - 3.4 8.1 6.7 21 5.6 0.1 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) SNARE PF05739.19 OWF36058.1 - 4 7.5 0.0 4 7.5 0.0 5.1 7 0 0 7 7 3 0 SNARE domain Phasin PF05597.11 OWF36058.1 - 6.5 6.8 6.5 14 5.7 0.3 3.5 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AIP3 PF03915.13 OWF36058.1 - 6.5 5.7 8.2 4 6.4 0.3 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 Pkinase PF00069.25 OWF36059.1 - 6.3e-56 189.7 0.0 7.7e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF36059.1 - 9.3e-38 130.0 0.0 1.3e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF36059.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OWF36059.1 - 7.2e-05 22.0 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OWF36059.1 - 0.025 13.6 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OWF36059.1 - 0.03 13.1 0.0 0.068 11.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase MFS_1 PF07690.16 OWF36060.1 - 6.8e-31 107.5 42.8 3.6e-24 85.4 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF36060.1 - 4.2e-05 23.0 20.2 0.0092 15.3 9.9 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Prp18 PF02840.15 OWF36060.1 - 0.017 15.2 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Prp18 domain AAA PF00004.29 OWF36061.1 - 8.6e-41 139.5 0.0 1.8e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OWF36061.1 - 2.1e-19 69.2 0.0 4.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OWF36061.1 - 3.1e-09 36.5 0.3 9.1e-09 35.0 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OWF36061.1 - 3.7e-06 27.4 1.0 0.0013 19.1 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OWF36061.1 - 1.2e-05 25.3 0.2 6.2e-05 23.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OWF36061.1 - 0.00015 21.6 0.2 0.00053 19.8 0.0 2.0 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OWF36061.1 - 0.00015 21.0 0.0 0.0003 20.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 OWF36061.1 - 0.00049 20.3 0.0 0.0022 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OWF36061.1 - 0.002 18.4 0.6 0.097 12.9 0.1 2.5 1 1 0 2 2 2 1 AAA domain DUF3713 PF12506.8 OWF36061.1 - 0.031 14.6 1.8 0.15 12.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) ATPase PF06745.13 OWF36061.1 - 0.036 13.4 0.9 0.22 10.8 0.0 2.5 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.21 OWF36061.1 - 0.036 13.4 0.1 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 OWF36061.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 OWF36061.1 - 0.047 13.4 0.1 0.35 10.5 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.16 OWF36061.1 - 0.048 13.1 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 OWF36061.1 - 0.049 13.8 0.2 0.11 12.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OWF36061.1 - 0.078 12.6 1.7 0.37 10.3 0.4 2.2 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF36061.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 OWF36061.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OWF36061.1 - 0.11 12.4 0.7 2.2 8.2 0.1 2.3 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 OWF36061.1 - 0.11 12.1 0.2 0.32 10.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OWF36061.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1192 PF06698.11 OWF36061.1 - 0.12 12.4 1.7 0.43 10.7 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Ras PF00071.22 OWF36062.1 - 8e-38 129.6 0.0 1e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF36062.1 - 1.1e-19 70.8 0.0 1.7e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 OWF36062.1 - 7.6e-08 32.6 0.4 1.8e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 SOCS box Arf PF00025.21 OWF36062.1 - 0.00099 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Pribosyl_synth PF14572.6 OWF36064.1 - 5.7e-96 319.8 0.8 8.5e-96 319.3 0.8 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OWF36064.1 - 4.2e-38 129.9 1.0 5.4e-38 129.5 0.2 1.6 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OWF36064.1 - 6.3e-06 25.8 0.1 2.8e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain HhH-GPD PF00730.25 OWF36065.1 - 1.5e-18 67.2 0.0 2.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OWF36065.1 - 6.5e-08 32.1 0.0 1.9e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif NRIP1_repr_3 PF15689.5 OWF36065.1 - 0.3 11.4 1.7 7.9 6.9 0.4 2.8 2 1 1 3 3 3 0 Nuclear receptor-interacting protein 1 repression 3 EndIII_4Fe-2S PF10576.9 OWF36065.1 - 0.5 10.8 2.9 1.3 9.5 2.9 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III ABC_tran PF00005.27 OWF36066.1 - 2.1e-55 187.0 0.1 1.2e-29 103.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OWF36066.1 - 3.3e-50 171.1 67.1 2.4e-26 92.7 28.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OWF36066.1 - 4.2e-21 76.0 1.6 1.1e-07 32.0 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OWF36066.1 - 1.4e-06 28.3 0.6 0.0046 16.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OWF36066.1 - 1.5e-06 27.8 4.9 0.0057 16.4 0.2 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 OWF36066.1 - 6.8e-06 25.7 0.1 0.24 10.8 0.0 3.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OWF36066.1 - 9.9e-06 26.0 0.0 0.087 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OWF36066.1 - 1.6e-05 25.5 4.6 0.0068 16.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 OWF36066.1 - 0.0001 22.4 0.0 1 9.7 0.0 4.6 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 OWF36066.1 - 0.00015 21.6 1.1 0.44 10.2 0.0 4.4 4 1 0 5 5 4 1 AAA ATPase domain AAA_30 PF13604.6 OWF36066.1 - 0.00061 19.6 0.3 1.3 8.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 OWF36066.1 - 0.0023 17.5 0.8 0.49 10.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 OWF36066.1 - 0.0026 17.2 0.6 0.7 9.2 0.1 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OWF36066.1 - 0.0028 17.0 0.3 0.46 9.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 OWF36066.1 - 0.0031 17.6 0.7 1.7 8.8 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MukB PF04310.12 OWF36066.1 - 0.0036 17.1 2.6 1.9 8.2 0.2 2.6 2 0 0 2 2 2 2 MukB N-terminal AAA_22 PF13401.6 OWF36066.1 - 0.0045 17.3 0.6 4.2 7.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane PF01061.24 OWF36066.1 - 0.0052 16.2 51.3 0.024 14.1 20.8 3.5 3 0 0 3 3 3 1 ABC-2 type transporter SRP54 PF00448.22 OWF36066.1 - 0.012 15.2 1.5 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 OWF36066.1 - 0.023 14.3 0.4 11 5.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OWF36066.1 - 0.024 15.0 0.1 5.2 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 OWF36066.1 - 0.026 14.6 0.1 16 5.5 0.0 3.9 4 1 1 5 5 4 0 AAA domain AAA_24 PF13479.6 OWF36066.1 - 0.029 14.1 0.4 3.7 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OWF36066.1 - 0.037 14.0 0.4 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OWF36066.1 - 0.039 14.1 0.0 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OWF36066.1 - 0.06 13.3 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 OWF36066.1 - 0.083 12.0 0.1 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 OWF36066.1 - 0.12 12.7 0.7 9.2 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF3153 PF11353.8 OWF36066.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) MeaB PF03308.16 OWF36066.1 - 0.12 11.3 1.0 0.83 8.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 OWF36066.1 - 0.15 11.1 1.0 0.93 8.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 OWF36066.1 - 0.15 11.9 1.2 4.5 7.2 0.2 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 OWF36066.1 - 0.16 11.5 0.4 8.9 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 OWF36066.1 - 0.17 12.1 0.1 7.3 6.8 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OWF36066.1 - 0.17 11.6 0.5 4.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 OWF36066.1 - 0.19 11.2 1.0 11 5.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 OWF36066.1 - 0.2 10.9 0.9 0.75 9.1 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 OWF36066.1 - 0.23 11.5 0.3 6.1 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 OWF36066.1 - 0.83 9.7 3.7 1.4 9.0 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain AAA PF00004.29 OWF36066.1 - 1.6 9.1 4.4 25 5.3 0.6 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IP_trans PF02121.18 OWF36067.1 - 1.4e-25 90.3 0.1 1.6e-25 90.2 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF5052 PF16475.5 OWF36068.1 - 0.0003 20.5 1.2 0.97 9.0 0.0 4.9 2 2 4 6 6 6 1 Domain of unknown function (DUF5052) KTSC PF13619.6 OWF36068.1 - 0.0012 18.6 16.8 3.3 7.6 0.1 10.1 6 3 7 14 14 14 1 KTSC domain DUF2442 PF10387.9 OWF36068.1 - 0.0033 17.7 14.4 1.1e+02 3.2 0.0 11.0 7 4 3 12 12 12 0 Protein of unknown function (DUF2442) KTSC PF13619.6 OWF36069.1 - 0.00019 21.2 3.8 11 5.9 0.0 5.8 2 2 5 7 7 7 1 KTSC domain Rib PF08428.10 OWF36069.1 - 0.0015 18.5 0.3 68 3.6 0.1 4.9 5 1 1 6 6 6 0 Rib/alpha-like repeat Spo0A_C PF08769.11 OWF36069.1 - 0.024 14.7 0.1 23 5.1 0.0 3.7 3 2 2 5 5 5 0 Sporulation initiation factor Spo0A C terminal CBM_26 PF16824.5 OWF36069.1 - 0.18 11.9 0.8 50 4.1 0.0 4.0 1 1 4 5 5 5 0 C-terminal carbohydrate-binding module DUF3634 PF12321.8 OWF36069.1 - 0.39 11.1 3.5 63 4.0 0.1 4.0 2 1 1 4 4 4 0 Protein of unknown function (DUF3634) GhoS PF11080.8 OWF36069.1 - 0.49 10.4 4.7 1.7 8.7 0.2 3.3 2 2 1 3 3 3 0 Endoribonuclease GhoS Glyco_hydro_32C PF08244.12 OWF36070.1 - 4.9e-05 23.4 3.3 3.3 7.7 0.4 5.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 C terminal Beta_helix_2 PF18835.1 OWF36070.1 - 0.0013 18.5 2.0 8.2 6.3 0.1 4.2 1 1 3 5 5 5 1 Beta helix repeat of Inulin fructotransferase Centro_C10orf90 PF17730.1 OWF36070.1 - 0.051 12.4 0.1 6.8 5.3 0.0 3.2 4 0 0 4 4 4 0 Centrosomal C10orf90 DUF1175 PF06672.11 OWF36070.1 - 0.073 12.8 17.2 1.7 8.3 0.6 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1175) LBP_C PF17386.2 OWF36070.1 - 0.15 11.9 35.5 18 5.3 0.1 10.5 5 4 6 11 11 11 0 Lacto-N-biose phosphorylase C-terminal domain Gal-bind_lectin PF00337.22 OWF36070.1 - 0.19 11.2 7.2 26 4.3 0.2 4.8 1 1 3 4 4 4 0 Galactoside-binding lectin DUF951 PF06107.11 OWF36070.1 - 0.34 10.8 11.0 28 4.7 0.1 5.9 1 1 6 9 9 9 0 Bacterial protein of unknown function (DUF951) Flu_C_NS1 PF03506.13 OWF36070.1 - 1.9 8.5 16.4 17 5.4 1.6 4.3 1 1 3 4 4 4 0 Influenza C non-structural protein (NS1) Fibrinogen_C PF00147.18 OWF36071.1 - 3.2e-45 154.7 0.3 4.6e-45 154.1 0.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF36071.1 - 0.0003 20.7 1.6 0.00079 19.3 1.6 1.7 1 0 0 1 1 1 1 PAN domain SOBP PF15279.6 OWF36072.1 - 2.5e-48 166.4 43.1 2.5e-48 166.4 43.1 3.4 3 1 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.14 OWF36072.1 - 0.0057 16.6 15.0 0.022 14.7 3.2 2.6 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif CUE PF02845.16 OWF36076.1 - 4e-16 58.4 0.1 8.5e-16 57.3 0.1 1.6 1 0 0 1 1 1 1 CUE domain C2 PF00168.30 OWF36076.1 - 5.6e-15 55.5 0.0 8.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain BIR PF00653.21 OWF36077.1 - 7.6e-54 180.3 23.4 2.6e-22 79.2 1.3 4.4 4 1 0 4 4 4 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF36077.1 - 7.2e-11 41.8 14.6 7.2e-11 41.8 14.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF36077.1 - 0.074 12.9 19.1 0.019 14.8 15.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 TssO PF17561.2 OWF36078.1 - 0.011 15.9 0.3 0.049 13.8 0.0 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO MLANA PF14991.6 OWF36078.1 - 2.6 8.3 5.1 6.9 7.0 0.4 2.2 1 1 1 2 2 2 0 Protein melan-A Hairy_orange PF07527.13 OWF36079.1 - 1.1e-05 25.5 0.0 3.8e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Hairy Orange CENP-O PF09496.10 OWF36079.1 - 0.054 13.5 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component RINGv PF12906.7 OWF36080.1 - 5.4e-10 39.2 12.4 9.8e-10 38.4 12.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OWF36080.1 - 0.00016 21.9 9.5 0.00034 20.9 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OWF36080.1 - 0.026 14.7 6.4 0.069 13.3 6.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Abhydrolase_9_N PF15420.6 OWF36080.1 - 0.047 13.7 1.8 0.076 13.0 1.8 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Cyt_bd_oxida_I PF01654.17 OWF36080.1 - 0.053 12.1 0.3 0.18 10.4 0.1 1.7 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit I STE2 PF02116.15 OWF36080.1 - 0.08 12.2 1.1 0.11 11.8 1.1 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR zf-RING-like PF08746.11 OWF36080.1 - 0.1 12.9 9.4 0.32 11.4 9.4 1.9 1 1 0 1 1 1 0 RING-like domain DUF3357 PF11837.8 OWF36080.1 - 0.32 11.5 1.9 4.5 7.8 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) zf-C3HC4 PF00097.25 OWF36080.1 - 0.99 9.3 6.4 4.2 7.3 6.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trypsin PF00089.26 OWF36081.1 - 9.1e-11 42.0 0.0 5.5e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF36081.1 - 8.8e-09 36.4 0.0 3.4e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain GlgX_C PF18390.1 OWF36081.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain CcmD PF04995.14 OWF36081.1 - 0.29 11.3 2.1 0.56 10.3 2.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Mcm10 PF09332.11 OWF36082.1 - 1.7e-72 244.8 23.3 6.8e-72 242.8 18.8 5.3 3 2 2 5 5 5 2 Mcm10 replication factor zf-primase PF09329.11 OWF36082.1 - 5e-16 58.2 3.5 5e-16 58.2 3.5 2.1 2 0 0 2 2 2 1 Primase zinc finger SRP_SPB PF02978.19 OWF36082.1 - 0.047 14.3 3.4 0.11 13.1 0.0 3.2 3 0 0 3 3 3 0 Signal peptide binding domain HypA PF01155.19 OWF36082.1 - 0.4 10.7 11.5 57 3.8 11.5 2.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MIF4G PF02854.19 OWF36083.1 - 5.7e-70 235.2 13.3 1.1e-35 123.2 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 OWF36083.1 - 1e-30 107.2 3.8 1e-30 107.2 3.8 4.8 5 1 1 6 6 6 1 Up-frameshift suppressor 2 TIMP PF00965.17 OWF36084.1 - 2.9e-15 56.5 11.0 4.8e-15 55.8 11.0 1.4 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF36084.1 - 8.2e-05 22.4 0.7 0.00013 21.7 0.7 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.17 OWF36085.1 - 6e-15 55.5 6.0 8.1e-15 55.1 6.0 1.2 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Tenui_PVC2 PF06656.11 OWF36085.1 - 0.0012 16.8 1.4 0.0015 16.6 1.4 1.1 1 0 0 1 1 1 1 Tenuivirus PVC2 protein NtA PF03146.15 OWF36085.1 - 0.048 13.5 0.1 0.082 12.8 0.1 1.4 1 1 0 1 1 1 0 Agrin NtA domain TIMP PF00965.17 OWF36086.1 - 2.4e-08 34.0 6.1 5.7e-08 32.8 6.1 1.6 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF36086.1 - 0.0012 18.6 0.4 0.0026 17.5 0.3 1.8 1 1 0 1 1 1 1 UNC-6/NTR/C345C module Nodulin-like PF06813.13 OWF36087.1 - 0.0045 16.5 0.2 0.005 16.4 0.2 1.1 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 OWF36088.1 - 7.9e-08 31.6 11.0 9.3e-08 31.4 11.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OWF36088.1 - 0.01 15.5 1.8 0.01 15.5 1.8 1.7 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OWF36089.1 - 6e-29 101.1 42.2 1.7e-24 86.4 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OWF36089.1 - 4.4e-17 62.4 5.3 4.4e-17 62.4 5.3 2.4 2 1 0 2 2 2 1 Nodulin-like Phage_holin_5_2 PF16079.5 OWF36089.1 - 2.2 8.7 7.9 2.8 8.3 1.6 3.7 2 2 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V IBN_N PF03810.19 OWF36090.1 - 9.3e-14 51.1 0.1 2.1e-12 46.8 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OWF36090.1 - 1.9e-06 28.0 4.7 4.3e-05 23.6 0.0 4.9 6 0 0 6 6 6 1 Exportin 1-like protein DNA_pol_phi PF04931.13 OWF36090.1 - 9.2 4.2 9.7 23 2.9 9.7 1.7 1 0 0 1 1 1 0 DNA polymerase phi Ribophorin_I PF04597.14 OWF36091.1 - 1.3e-140 469.6 5.9 1.8e-140 469.0 5.9 1.2 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.6 OWF36091.1 - 2.3e-05 25.0 2.3 5.8e-05 23.7 2.3 1.7 1 0 0 1 1 1 1 DNA repair REX1-B DUF4407 PF14362.6 OWF36091.1 - 0.00031 20.2 2.3 0.00051 19.5 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) UPF0449 PF15136.6 OWF36091.1 - 0.0022 18.4 4.0 0.0022 18.4 4.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 AAA_13 PF13166.6 OWF36091.1 - 0.016 13.9 9.6 0.023 13.4 9.6 1.1 1 0 0 1 1 1 0 AAA domain DUF5082 PF16888.5 OWF36091.1 - 0.034 14.4 4.1 0.1 12.9 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 OWF36091.1 - 0.058 14.0 4.5 0.43 11.2 0.3 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2203 PF09969.9 OWF36091.1 - 1.4 9.6 7.0 0.27 12.0 1.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TPR_MLP1_2 PF07926.12 OWF36091.1 - 1.7 8.7 13.8 2.2 8.3 13.0 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 OWF36091.1 - 1.9 9.0 9.8 3.2 8.3 9.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FlxA PF14282.6 OWF36091.1 - 4.6 7.3 18.5 0.88 9.6 12.5 2.3 1 1 1 2 2 2 0 FlxA-like protein Csm1_N PF18504.1 OWF36091.1 - 6.1 7.3 10.7 1.6 9.1 1.8 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain zf-C2H2_4 PF13894.6 OWF36092.1 - 9.4e-05 22.9 31.5 0.072 14.0 0.7 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF36092.1 - 0.014 15.8 23.7 2.1 8.9 0.4 6.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type 7tm_3 PF00003.22 OWF36093.1 - 1.4e-39 136.3 23.8 1.9e-39 135.8 23.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Phage_holin_2_3 PF16080.5 OWF36093.1 - 0.0064 16.2 0.3 0.023 14.4 0.3 2.0 1 0 0 1 1 1 1 Bacteriophage holin family HP1 FPP PF05911.11 OWF36093.1 - 0.056 11.6 1.1 0.086 11.0 1.1 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4618 PF15397.6 OWF36093.1 - 0.1 12.0 1.3 0.18 11.2 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Sec2p PF06428.11 OWF36093.1 - 0.29 11.2 1.4 0.53 10.3 1.4 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Ig_3 PF13927.6 OWF36094.1 - 4.4e-50 168.2 4.6 2.7e-14 53.5 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 OWF36094.1 - 3.9e-47 158.2 0.8 1.2e-10 41.3 0.0 6.5 5 1 1 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF36094.1 - 1.2e-34 118.4 5.6 1.3e-08 35.1 0.0 6.6 5 1 1 6 6 6 6 Immunoglobulin domain ig PF00047.25 OWF36094.1 - 2e-31 108.0 12.7 6.8e-06 26.2 0.0 6.8 6 1 0 6 6 6 6 Immunoglobulin domain F5_F8_type_C PF00754.25 OWF36094.1 - 2.8e-22 79.2 1.6 3e-22 79.1 0.4 1.7 2 0 0 2 2 2 1 F5/8 type C domain V-set PF07686.17 OWF36094.1 - 8.5e-14 51.6 12.0 0.01 16.0 0.0 9.0 6 5 0 6 6 6 4 Immunoglobulin V-set domain C1-set PF07654.15 OWF36094.1 - 5.4e-08 33.1 5.7 0.0036 17.7 0.2 6.3 6 0 0 6 6 6 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 OWF36094.1 - 1.4e-07 31.0 0.0 1.4 8.5 0.0 5.6 5 0 0 5 5 5 2 Immunoglobulin domain C2-set_2 PF08205.12 OWF36094.1 - 2e-06 27.8 0.2 0.093 12.8 0.0 5.0 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF36094.1 - 3e-06 27.2 0.6 0.84 9.7 0.0 5.0 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain DUF4381 PF14316.6 OWF36094.1 - 0.086 13.1 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PMP22_Claudin PF00822.20 OWF36095.1 - 2.2e-07 30.9 13.9 3e-07 30.4 13.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF36095.1 - 5.7e-07 29.5 15.5 1.1e-06 28.5 15.4 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF36095.1 - 0.05 13.6 15.4 0.88 9.5 15.4 2.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Clc-like PF07062.12 OWF36095.1 - 0.56 9.6 17.4 32 3.9 17.4 2.3 1 1 0 1 1 1 0 Clc-like 5TM-5TMR_LYT PF07694.12 OWF36095.1 - 2.2 7.8 8.9 0.19 11.2 2.5 2.2 2 1 0 2 2 2 0 5TMR of 5TMR-LYT DUF4199 PF13858.6 OWF36095.1 - 3.5 8.0 9.7 1.2 9.6 3.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) MFS_1 PF07690.16 OWF36096.1 - 1.3e-40 139.4 49.5 6.9e-27 94.3 27.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF36096.1 - 3.1e-12 46.5 19.7 6.4e-10 38.9 8.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4278 PF14105.6 OWF36098.1 - 9e-12 45.2 0.5 0.03 14.7 0.2 6.6 1 1 3 4 4 4 4 Domain of unknown function (DUF4278) LSM14 PF12701.7 OWF36098.1 - 6.9e-07 29.3 0.1 22 5.2 0.0 8.5 1 1 11 12 12 12 0 Scd6-like Sm domain DUF1270 PF06900.11 OWF36098.1 - 8.2e-05 22.9 0.2 1.4e+02 2.9 0.0 6.1 2 2 4 6 6 6 0 Protein of unknown function (DUF1270) Ins145_P3_rec PF08709.11 OWF36098.1 - 0.00018 20.8 0.0 28 3.8 0.0 5.3 2 1 6 8 8 8 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Metallothio_Pro PF02069.16 OWF36098.1 - 0.00074 19.7 13.3 33 4.8 0.0 7.0 3 1 4 7 7 7 0 Prokaryotic metallothionein UPF0147 PF03685.13 OWF36098.1 - 0.0009 19.3 0.0 80 3.4 0.0 5.7 2 2 3 7 7 7 0 Uncharacterised protein family (UPF0147) Adenine_deam_C PF13382.6 OWF36098.1 - 0.0024 17.2 0.0 20 4.5 0.0 4.3 3 1 4 7 7 7 1 Adenine deaminase C-terminal domain DUF269 PF03270.13 OWF36098.1 - 0.25 11.5 0.0 34 4.5 0.0 3.7 3 2 1 4 4 4 0 Protein of unknown function, DUF269 Put_DNA-bind_N PF06971.13 OWF36098.1 - 0.73 9.9 8.0 23 5.1 0.3 4.3 4 1 1 5 5 5 0 Putative DNA-binding protein N-terminus Xin PF08043.12 OWF36099.1 - 0.00044 19.7 7.0 7e+02 0.1 0.0 11.2 13 0 0 13 13 13 0 Xin repeat zf-RING_UBOX PF13445.6 OWF36100.1 - 5.4e-11 42.3 2.5 5.4e-11 42.3 2.5 4.7 4 1 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF36100.1 - 4e-08 33.0 6.1 4e-08 33.0 6.1 4.7 3 3 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF36100.1 - 1.5e-06 27.9 4.0 1.5e-06 27.9 4.0 4.9 6 0 0 6 6 4 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF36100.1 - 1.6e-06 27.9 0.2 0.054 13.6 0.1 4.5 4 0 0 4 4 4 1 NHL repeat zf-RING_5 PF14634.6 OWF36100.1 - 1.9e-06 27.7 5.3 1.9e-06 27.7 5.3 4.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF36100.1 - 5.6e-06 26.4 3.0 5.6e-06 26.4 3.0 4.8 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF36100.1 - 2.3e-05 24.2 1.5 2.3e-05 24.2 1.5 4.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF36100.1 - 3.5e-05 23.9 9.6 3.5e-05 23.9 9.6 4.2 5 1 0 5 5 3 2 B-box zinc finger zf-RING_2 PF13639.6 OWF36100.1 - 0.00016 21.9 9.7 0.00016 21.9 9.7 5.1 4 1 0 4 4 3 1 Ring finger domain APG17 PF04108.12 OWF36100.1 - 0.0019 17.4 4.7 0.0028 16.8 4.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Prok-RING_4 PF14447.6 OWF36100.1 - 0.0085 15.9 3.2 0.0085 15.9 3.2 4.9 5 0 0 5 5 3 1 Prokaryotic RING finger family 4 UPF0242 PF06785.11 OWF36100.1 - 0.015 15.4 4.2 0.025 14.7 4.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Clathrin_lg_ch PF01086.17 OWF36100.1 - 0.023 14.7 1.1 0.023 14.7 1.1 1.8 2 0 0 2 2 1 0 Clathrin light chain Cor1 PF04803.12 OWF36100.1 - 0.052 13.8 5.7 0.15 12.3 3.0 2.5 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region SGL PF08450.12 OWF36100.1 - 0.11 12.0 1.2 2.5 7.6 0.0 2.9 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Peptidase_M15_2 PF05951.13 OWF36100.1 - 0.14 11.8 0.2 0.33 10.6 0.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DUF1640 PF07798.11 OWF36100.1 - 0.15 12.1 7.6 0.31 11.1 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Pkinase_Tyr PF07714.17 OWF36101.1 - 6.3e-19 68.3 0.0 7.6e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF36101.1 - 2.2e-17 63.3 0.0 2.8e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain BTG PF07742.12 OWF36102.1 - 2.6e-37 127.2 0.0 4.7e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 BTG family DUF913 PF06025.12 OWF36103.1 - 1.8e-115 385.9 0.2 1.8e-115 385.9 0.2 7.4 10 1 0 10 10 10 2 Domain of Unknown Function (DUF913) HECT PF00632.25 OWF36103.1 - 6.2e-88 295.2 1.0 1.1e-87 294.4 1.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 OWF36103.1 - 9.5e-27 91.6 29.3 6.5e-10 38.1 1.2 5.3 5 0 0 5 5 5 3 Ubiquitin binding region DUF908 PF06012.12 OWF36103.1 - 8.4e-26 91.2 10.7 8e-16 58.4 2.0 6.6 6 1 1 7 7 7 2 Domain of Unknown Function (DUF908) WWE PF02825.20 OWF36103.1 - 9.2e-15 55.0 0.8 3.6e-14 53.1 0.8 2.2 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 OWF36103.1 - 3.9e-07 29.8 0.0 2.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2 PF00096.26 OWF36104.1 - 9.4e-14 51.0 36.5 0.00048 20.4 0.3 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF36104.1 - 1.1e-12 47.6 36.4 0.0029 18.3 0.2 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-Di19 PF05605.12 OWF36104.1 - 9.7e-08 32.2 26.2 0.0041 17.4 2.8 4.4 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 OWF36104.1 - 3.7e-07 30.3 37.5 0.0081 16.5 0.4 7.4 8 0 0 8 8 8 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF36104.1 - 4.9e-07 29.4 27.2 0.00037 20.2 4.9 5.2 5 0 0 5 5 5 3 C2H2-type zinc-finger domain FOXP-CC PF16159.5 OWF36104.1 - 0.0055 17.3 16.7 0.01 16.5 0.1 4.7 3 2 1 4 4 4 1 FOXP coiled-coil domain zf-met PF12874.7 OWF36104.1 - 0.0078 16.6 0.3 0.0078 16.6 0.3 5.3 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF36104.1 - 0.011 16.0 0.4 0.011 16.0 0.4 5.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 OWF36104.1 - 0.029 14.0 21.1 0.057 13.1 0.4 4.6 2 2 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-MYST PF17772.1 OWF36104.1 - 3 7.5 16.1 2.6 7.7 1.3 4.6 4 1 1 5 5 5 0 MYST family zinc finger domain Lipase_GDSL_2 PF13472.6 OWF36106.1 - 7.8e-06 26.4 0.0 9e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF36106.1 - 0.0024 17.9 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF36107.1 - 8.4e-09 36.1 0.0 1.1e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF36107.1 - 0.0032 17.5 0.1 0.0097 15.9 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Retrotrans_gag PF03732.17 OWF36108.1 - 0.0029 17.8 1.9 0.0029 17.8 1.9 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein PFEMP PF03011.15 OWF36108.1 - 0.084 13.5 2.1 0.12 13.0 2.1 1.2 1 0 0 1 1 1 0 PFEMP DBL domain LMBR1 PF04791.16 OWF36108.1 - 0.2 10.5 1.2 0.27 10.1 1.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Erv26 PF04148.13 OWF36109.1 - 3.9e-52 177.1 19.3 1.9e-51 174.8 19.3 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Mg_trans_NIPA PF05653.14 OWF36109.1 - 0.11 11.6 13.4 0.02 14.0 9.5 1.6 1 1 1 2 2 2 0 Magnesium transporter NIPA HSP70 PF00012.20 OWF36110.1 - 3.7e-262 870.9 15.2 4.4e-262 870.6 15.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF36110.1 - 2.5e-17 62.7 0.7 9.9e-14 50.9 0.1 2.6 1 1 1 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OWF36110.1 - 0.0002 21.8 3.7 0.045 14.2 0.0 3.8 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 OWF36110.1 - 0.0013 18.6 0.1 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain MukF_M PF17192.4 OWF36110.1 - 0.0036 17.1 1.5 0.0074 16.0 1.5 1.5 1 0 0 1 1 1 1 MukF middle domain FIVAR PF07554.13 OWF36110.1 - 7.4 7.4 10.2 1.2e+02 3.6 10.2 2.8 1 1 0 1 1 1 0 FIVAR domain Pkinase PF00069.25 OWF36111.1 - 7.6e-64 215.6 0.5 1e-63 215.2 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF36111.1 - 1.5e-37 129.3 0.2 2.1e-37 128.9 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF36111.1 - 1.3e-12 47.6 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF36111.1 - 0.00062 18.7 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OWF36111.1 - 0.0019 17.2 0.2 0.0032 16.4 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF36111.1 - 0.007 16.3 0.2 0.012 15.6 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cdd1 PF11731.8 OWF36111.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Pathogenicity locus Kdo PF06293.14 OWF36111.1 - 0.13 11.6 0.4 0.25 10.7 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TACC_C PF05010.14 OWF36112.1 - 6.9e-19 68.4 33.0 1.1e-18 67.7 33.0 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Formin_GBD_N PF18382.1 OWF36112.1 - 0.035 14.6 30.0 4.2 7.9 0.1 9.9 8 2 2 10 10 10 0 Formin N-terminal GTPase-binding domain Mto2_bdg PF12808.7 OWF36112.1 - 0.09 13.1 3.5 0.18 12.1 1.5 2.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FAA_hydrolase PF01557.18 OWF36112.1 - 1.1 8.9 5.9 23 4.6 0.1 4.3 3 1 1 4 4 4 0 Fumarylacetoacetate (FAA) hydrolase family Nup88 PF10168.9 OWF36112.1 - 2.8 5.7 21.8 1.7 6.3 19.9 1.4 1 1 0 1 1 1 0 Nuclear pore component bZIP_2 PF07716.15 OWF36112.1 - 5.7 7.1 11.9 11 6.2 1.5 2.9 2 0 0 2 2 2 0 Basic region leucine zipper zf-C4 PF00105.18 OWF36114.1 - 2.1e-32 111.4 11.4 3.7e-32 110.6 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF36114.1 - 4.8e-18 65.5 1.3 8.9e-18 64.6 1.3 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Vps16_N PF04841.13 OWF36114.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region C1q PF00386.21 OWF36116.1 - 3.7e-21 75.7 0.0 5.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 C1q domain tRNA_Me_trans PF03054.16 OWF36117.1 - 9.1e-118 393.1 0.0 1e-117 392.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 OWF36117.1 - 2.7e-06 26.7 0.0 1.5e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 OWF36117.1 - 6.3e-05 22.6 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 OWF36117.1 - 0.00039 20.0 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 OWF36117.1 - 0.0049 16.6 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 OWF36117.1 - 0.0062 16.2 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Myotub-related PF06602.14 OWF36118.1 - 0.00054 19.0 0.0 0.0022 17.0 0.0 1.9 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 OWF36118.1 - 0.00078 19.5 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Bim_N PF06773.11 OWF36118.1 - 0.04 13.6 1.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Bim protein N-terminus p450 PF00067.22 OWF36119.1 - 1.2e-109 367.2 0.0 1.5e-109 366.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 OWF36120.1 - 1.3e-23 83.4 0.0 2e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OWF36120.1 - 1e-22 80.1 0.0 2.1e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OWF36120.1 - 2.3e-10 41.6 0.0 4.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OWF36121.1 - 1e-18 67.5 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF36121.1 - 8.1e-10 39.9 0.0 1.8e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OWF36121.1 - 0.0014 18.5 0.1 0.0032 17.3 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase zf-C2H2_4 PF13894.6 OWF36124.1 - 1e-119 380.7 381.0 0.0026 18.5 0.3 53.7 54 0 0 54 54 54 46 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF36124.1 - 1e-104 337.5 396.2 4.4e-05 23.7 4.3 53.6 54 0 0 54 54 54 39 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF36124.1 - 8.2e-49 163.0 278.9 2.4e-05 24.5 0.8 42.9 44 2 2 46 46 45 26 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF36124.1 - 8.3e-38 127.2 394.6 0.0075 16.7 0.4 51.6 53 0 0 53 53 52 28 Zinc-finger double domain zf-met PF12874.7 OWF36124.1 - 2.6e-36 122.9 281.3 0.0026 18.1 0.5 44.5 47 0 0 47 47 47 25 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OWF36124.1 - 1.5e-08 34.3 222.3 0.00012 21.8 6.5 36.9 34 7 7 41 41 41 11 zinc-finger C2H2-type zf-Di19 PF05605.12 OWF36124.1 - 4e-08 33.4 3.2 0.00014 22.1 0.2 30.3 11 10 22 34 34 33 10 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OWF36124.1 - 1.9e-05 24.5 2.8 0.00035 20.5 0.4 49.6 51 4 2 53 53 51 19 C2H2-type zinc finger zf_Hakai PF18408.1 OWF36124.1 - 0.00032 20.3 36.2 10 5.9 0.0 12.3 9 0 0 9 9 9 2 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 OWF36124.1 - 0.00032 20.9 193.3 0.031 14.6 7.0 20.2 5 3 16 22 22 22 11 C2H2-type zinc ribbon ADK_lid PF05191.14 OWF36124.1 - 0.0013 18.6 1.2 0.0013 18.6 1.2 26.9 22 7 8 30 30 29 5 Adenylate kinase, active site lid zf_UBZ PF18439.1 OWF36124.1 - 0.0075 15.8 1.8 0.0075 15.8 1.8 38.9 49 0 0 49 49 45 4 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 OWF36124.1 - 0.015 15.2 0.1 0.015 15.2 0.1 39.4 46 0 0 46 46 43 0 zinc-finger of a C2HC-type MG3 PF17791.1 OWF36124.1 - 0.017 15.4 1.7 33 4.8 0.1 5.3 3 0 0 3 3 3 0 Macroglobulin domain MG3 AAA_lid_10 PF17872.1 OWF36124.1 - 0.062 13.4 5.8 6.5 7.0 0.2 3.7 4 0 0 4 4 4 0 AAA lid domain Amidase PF01425.21 OWF36125.1 - 1.1e-100 337.7 0.0 1.4e-100 337.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Meiosis_expr PF15163.6 OWF36126.1 - 4.4e-36 123.4 4.6 5.2e-36 123.2 4.6 1.1 1 0 0 1 1 1 1 Meiosis-expressed MADF_DNA_bdg PF10545.9 OWF36127.1 - 4e-05 23.8 0.1 8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like GlyL_C PF12524.8 OWF36127.1 - 0.00078 19.5 2.4 0.08 13.1 0.4 2.9 2 1 1 3 3 3 2 dsDNA virus glycoprotein L C terminal Fibrinogen_C PF00147.18 OWF36129.1 - 1.5e-54 185.2 2.6 1.8e-54 184.9 2.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain His_Phos_2 PF00328.22 OWF36130.1 - 2.4e-19 69.9 0.1 3.3e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DapH_N PF08503.10 OWF36130.1 - 0.012 15.8 0.0 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal TssD PF17642.1 OWF36132.1 - 0.00018 21.3 1.0 0.64 9.9 0.1 3.1 1 1 2 3 3 3 3 Hemolysin coregulated protein Hcp (TssD) VWA_3 PF13768.6 OWF36132.1 - 0.0035 17.3 2.3 6.5 6.7 0.1 3.0 1 1 2 3 3 3 2 von Willebrand factor type A domain MHCassoc_trimer PF08831.10 OWF36132.1 - 0.13 12.3 3.5 76 3.4 0.1 3.8 2 1 3 5 5 5 0 Class II MHC-associated invariant chain trimerisation domain CheY-binding PF09078.11 OWF36132.1 - 0.14 12.3 0.9 3.9 7.7 0.0 2.7 3 0 0 3 3 3 0 CheY binding Pox_VP8_L4R PF04498.12 OWF36132.1 - 0.35 10.4 4.9 4.2 6.9 0.8 2.8 1 1 2 3 3 3 0 Poxvirus nucleic acid binding protein VP8/L4R Peptidase_C26 PF07722.13 OWF36133.1 - 1.7e-20 73.7 0.0 3.9e-20 72.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 OWF36133.1 - 6.1e-11 42.4 0.0 9.3e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OWF36133.1 - 0.0012 18.8 0.0 0.0031 17.4 0.0 1.7 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 OWF36133.1 - 0.05 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Kinesin PF00225.23 OWF36134.1 - 2.6e-102 342.2 0.0 2.6e-102 342.2 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 OWF36134.1 - 3.3e-42 142.9 0.1 1.1e-41 141.2 0.1 2.0 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 OWF36134.1 - 4.7e-17 62.3 10.1 6.5e-17 61.9 0.0 3.8 4 0 0 4 4 4 1 Microtubule binding Crystall_4 PF17945.1 OWF36134.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 Beta/Gamma crystallin V_ATPase_I PF01496.19 OWF36134.1 - 2 6.3 8.6 2.9 5.7 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.8 OWF36134.1 - 3.2 6.9 16.9 0.23 10.7 11.6 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 BTB_2 PF02214.22 OWF36135.1 - 5.4e-25 87.6 0.0 1.2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 OWF36135.1 - 6.4e-18 64.9 20.6 9.2e-18 64.3 20.6 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF36135.1 - 2.6e-14 52.9 3.8 2.6e-14 52.9 3.8 2.1 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 OWF36135.1 - 6.4e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Serinc PF03348.15 OWF36136.1 - 9.8e-168 558.5 18.6 1.1e-167 558.3 18.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Oxidored_q3 PF00499.20 OWF36136.1 - 0.0044 16.7 4.9 0.0044 16.7 4.9 3.8 3 2 0 3 3 3 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 OATP PF03137.20 OWF36137.1 - 2e-55 188.1 5.2 2.4e-55 187.9 5.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF36137.1 - 2.6e-10 39.8 14.0 3.3e-09 36.1 14.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF36137.1 - 0.00059 18.8 1.5 0.00059 18.8 1.5 2.2 2 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 OWF36138.1 - 1.2e-85 287.9 7.6 1.4e-85 287.6 7.6 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF36138.1 - 1.1e-06 27.8 0.7 1.1e-06 27.8 0.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF36138.1 - 0.009 16.1 14.9 0.009 16.1 14.9 1.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Extensin_1 PF02095.15 OWF36138.1 - 0.38 11.1 1.8 0.71 10.2 1.8 1.5 1 0 0 1 1 1 0 Extensin-like protein repeat TIR PF01582.20 OWF36139.1 - 1.3e-22 80.4 0.2 2.1e-22 79.8 0.2 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF36139.1 - 1.6e-16 61.0 0.0 2.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 TIR domain EGF_2 PF07974.13 OWF36139.1 - 1e-06 29.0 94.2 0.081 13.3 12.7 7.4 5 2 1 6 6 6 6 EGF-like domain Stevor PF17410.2 OWF36139.1 - 0.021 14.4 0.1 0.021 14.4 0.1 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF3235 PF11574.8 OWF36139.1 - 0.21 12.5 0.1 0.67 10.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) DUF4381 PF14316.6 OWF36139.1 - 0.25 11.6 2.1 0.49 10.6 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-C2H2 PF00096.26 OWF36140.1 - 1.1e-11 44.5 21.5 1.3e-05 25.4 1.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF36140.1 - 2.7e-10 40.2 20.1 0.0013 19.4 0.7 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF36140.1 - 7.6e-10 38.8 18.4 1.4e-05 25.3 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF36140.1 - 0.00011 22.1 18.3 0.00011 22.1 0.2 4.0 3 1 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 OWF36140.1 - 0.0037 17.6 4.6 2 8.9 0.0 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.12 OWF36140.1 - 0.021 15.1 5.9 3 8.2 3.1 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 OWF36140.1 - 0.23 11.8 12.6 2.5 8.5 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 OWF36140.1 - 0.45 10.7 9.8 1.4 9.1 3.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 OWF36140.1 - 4.2 7.6 18.0 0.55 10.4 3.3 3.3 2 1 0 3 3 3 0 AN1-like Zinc finger p450 PF00067.22 OWF36141.1 - 1e-118 397.1 0.0 1.2e-118 396.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tma16 PF11176.8 OWF36141.1 - 0.016 15.1 0.8 0.025 14.4 0.8 1.3 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Peptidase_S78_2 PF14550.6 OWF36141.1 - 0.12 12.4 0.2 0.34 11.0 0.2 1.6 2 0 0 2 2 2 0 Putative phage serine protease XkdF Sulfotransfer_3 PF13469.6 OWF36142.1 - 1.8e-06 28.5 0.0 1.3 9.4 0.0 3.2 2 1 1 3 3 3 3 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF36142.1 - 0.00029 20.4 0.1 0.018 14.5 0.1 2.5 1 1 0 1 1 1 1 Sulfotransferase domain Trans_reg_C PF00486.28 OWF36143.1 - 0.014 15.4 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Presenilin PF01080.17 OWF36143.1 - 4.2 6.0 5.7 5.2 5.7 5.7 1.1 1 0 0 1 1 1 0 Presenilin 7tm_2 PF00002.24 OWF36145.1 - 1.5e-58 198.0 12.0 2e-58 197.6 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF36145.1 - 4.8e-12 46.0 6.1 9.3e-12 45.1 6.1 1.5 1 0 0 1 1 1 1 Hormone receptor domain DUF4079 PF13301.6 OWF36145.1 - 0.39 10.9 3.8 0.13 12.4 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2345 PF10106.9 OWF36146.1 - 0.032 14.1 0.5 0.038 13.9 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Adeno_shaft PF00608.17 OWF36146.1 - 0.73 9.7 3.4 5.9 6.8 1.4 2.3 1 1 1 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) VWA PF00092.28 OWF36148.1 - 4.6e-120 398.2 18.1 1.9e-40 139.0 0.4 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF36148.1 - 2.2e-48 163.3 3.4 8e-16 58.6 0.0 3.6 4 0 0 4 4 4 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF36148.1 - 1.1e-22 80.7 0.2 5.7e-08 32.9 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain NOG1 PF06858.14 OWF36148.1 - 0.0083 15.9 0.5 4.4 7.2 0.0 3.6 3 0 0 3 3 3 1 Nucleolar GTP-binding protein 1 (NOG1) Mucin PF01456.17 OWF36148.1 - 0.17 11.9 14.9 0.48 10.4 14.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein VWA PF00092.28 OWF36149.1 - 3.4e-118 392.2 16.9 1.5e-39 136.1 1.8 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF36149.1 - 9e-47 158.2 2.4 2.5e-14 53.8 0.0 3.5 4 0 0 4 4 4 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF36149.1 - 2.4e-23 82.8 0.2 8.6e-07 29.0 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF36149.1 - 0.0014 18.0 1.5 5.4 6.3 0.0 4.0 3 1 0 3 3 3 1 VWA domain containing CoxE-like protein Copine PF07002.16 OWF36149.1 - 0.011 15.2 1.2 5.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Copine LYTB PF02401.18 OWF36149.1 - 0.064 12.5 0.1 0.61 9.3 0.0 2.3 2 0 0 2 2 2 0 LytB protein Peripla_BP_6 PF13458.6 OWF36149.1 - 0.1 12.2 0.2 1.5 8.4 0.0 2.6 3 0 0 3 3 3 0 Periplasmic binding protein ETF PF01012.21 OWF36149.1 - 0.11 12.4 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Electron transfer flavoprotein domain DUF1194 PF06707.11 OWF36149.1 - 0.14 11.3 0.8 1.3 8.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) Laminin_G_2 PF02210.24 OWF36150.1 - 2.6e-145 477.2 20.5 3.3e-27 95.5 0.1 6.3 6 0 0 6 6 6 6 Laminin G domain Laminin_G_1 PF00054.23 OWF36150.1 - 5.2e-118 389.0 9.4 7.2e-23 81.2 0.0 6.3 6 0 0 6 6 6 6 Laminin G domain Laminin_G_3 PF13385.6 OWF36150.1 - 5.4e-14 52.6 6.2 0.002 18.3 0.2 6.0 6 0 0 6 6 6 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 OWF36150.1 - 3.6e-10 40.0 36.6 0.00036 20.8 6.3 4.3 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 OWF36150.1 - 1.4e-06 28.7 28.4 0.0016 19.0 2.2 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 OWF36150.1 - 0.25 11.7 12.9 3.2 8.1 2.2 2.7 2 0 0 2 2 2 0 Pvs28 EGF domain Cdd1 PF11731.8 OWF36151.1 - 1.1e-07 32.0 2.3 1.4 9.2 0.0 4.8 1 1 4 5 5 5 3 Pathogenicity locus RNA_pol_A_CTD PF03118.15 OWF36151.1 - 2.4e-06 27.2 7.0 0.46 10.3 0.1 5.9 1 1 5 6 6 6 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH_5 PF14520.6 OWF36151.1 - 1.1e-05 25.9 8.5 0.032 14.8 0.4 5.1 1 1 4 5 5 5 1 Helix-hairpin-helix domain Senescence PF06911.12 OWF36151.1 - 9.7e-05 22.8 0.5 3.1 8.1 0.0 4.1 1 1 4 5 5 5 1 Senescence-associated protein TfoX_C PF04994.13 OWF36151.1 - 0.00045 20.3 0.2 8.1 6.6 0.0 3.8 1 1 3 5 5 5 1 TfoX C-terminal domain Phasin_2 PF09361.10 OWF36151.1 - 0.00067 19.9 0.3 1.8 8.9 0.1 2.9 1 1 2 3 3 3 2 Phasin protein DNA_pol_lambd_f PF10391.9 OWF36151.1 - 0.0076 16.0 0.0 6.3 6.7 0.0 4.4 1 1 2 4 4 4 1 Fingers domain of DNA polymerase lambda KRAB PF01352.27 OWF36151.1 - 0.036 13.7 0.5 4e+02 0.8 0.0 6.2 8 0 0 8 8 8 0 KRAB box Endonuc-dimeris PF09124.10 OWF36151.1 - 0.18 12.0 0.1 1.9e+02 2.3 0.0 4.3 3 2 0 5 5 5 0 T4 recombination endonuclease VII, dimerisation DUF3701 PF12482.8 OWF36151.1 - 0.5 10.5 5.5 80 3.4 0.0 4.8 2 2 4 6 6 6 0 Phage integrase protein V-SNARE_C PF12352.8 OWF36151.1 - 4.3 7.7 6.1 31 4.9 0.1 4.1 5 0 0 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus TMEM72 PF16054.5 OWF36151.1 - 5 6.8 5.5 55 3.4 0.1 3.3 2 2 0 3 3 3 0 Transmembrane protein family 72 RFX5_N PF18326.1 OWF36152.1 - 0.00011 21.8 0.0 23 4.8 0.0 5.5 1 1 2 5 5 5 3 RFX5 N-terminal domain CPT PF07931.12 OWF36152.1 - 0.0038 17.1 0.8 3.2 7.6 0.1 2.7 1 1 2 3 3 3 2 Chloramphenicol phosphotransferase-like protein 17kDa_Anti_2 PF16998.5 OWF36152.1 - 0.1 12.5 9.2 35 4.4 0.1 4.8 1 1 5 6 6 6 0 17 kDa outer membrane surface antigen PDZ PF00595.24 OWF36153.1 - 3.2e-28 97.9 1.6 6.3e-14 52.1 0.2 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OWF36153.1 - 1.1e-18 66.7 1.7 2e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OWF36153.1 - 1.6e-09 38.0 0.1 5.7e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 OWF36153.1 - 0.0013 18.6 1.5 1.3 9.1 0.1 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 OWF36153.1 - 0.0024 18.3 0.3 1.3 9.4 0.0 2.8 2 1 0 2 2 2 2 PDZ domain Peptidase_M28 PF04389.17 OWF36154.1 - 1e-16 61.3 0.0 9.9e-11 41.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M28 PA PF02225.22 OWF36154.1 - 7.5e-13 48.3 0.0 2.3e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 PA domain zf-H2C2_2 PF13465.6 OWF36155.1 - 1.5e-84 274.9 53.9 2.2e-10 40.5 0.7 11.3 11 0 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.26 OWF36155.1 - 2.9e-57 188.1 59.2 2.5e-06 27.6 0.2 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF36155.1 - 4.2e-40 132.9 57.4 0.0022 18.7 0.3 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF36155.1 - 3.7e-26 90.6 56.9 0.0031 17.5 0.2 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF36155.1 - 4e-21 74.8 31.6 0.023 15.0 0.4 11.2 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF36155.1 - 9.6e-21 73.5 43.7 0.016 15.6 0.1 11.1 11 0 0 11 11 11 7 Zinc-finger of C2H2 type GAGA PF09237.11 OWF36155.1 - 7.1e-15 54.6 6.2 0.0066 16.2 0.0 7.4 5 2 3 8 8 8 4 GAGA factor zf-Di19 PF05605.12 OWF36155.1 - 1.7e-12 47.4 36.0 0.00041 20.6 0.3 6.3 4 1 2 7 7 7 5 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 OWF36155.1 - 7.3e-12 45.2 34.3 0.033 14.3 0.2 8.3 6 4 2 8 8 8 5 Zinc ribbon domain BolA PF01722.18 OWF36155.1 - 4e-10 39.8 6.0 0.078 13.3 0.0 6.6 3 2 0 5 5 5 1 BolA-like protein Zf_RING PF16744.5 OWF36155.1 - 1.2e-07 31.7 33.6 0.084 13.0 1.1 10.3 1 1 10 11 11 11 1 KIAA1045 RING finger zf-C2H2_11 PF16622.5 OWF36155.1 - 6.4e-07 29.0 37.3 0.54 10.1 0.1 10.2 11 0 0 11 11 11 3 zinc-finger C2H2-type zf-C2HE PF16278.5 OWF36155.1 - 1.6e-06 28.4 47.5 0.28 11.6 0.3 9.7 3 3 7 10 10 10 4 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 OWF36155.1 - 1e-05 25.6 42.0 0.012 15.7 7.2 6.7 1 1 3 6 6 6 3 FYVE zinc finger zf_UBZ PF18439.1 OWF36155.1 - 0.00014 21.4 33.3 8.9 6.0 0.1 10.5 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 OWF36155.1 - 0.00023 21.9 29.6 0.68 10.7 0.2 5.8 1 1 2 5 5 5 2 zinc-ribbon family DUF3268 PF11672.8 OWF36155.1 - 0.00026 21.3 26.5 2.7 8.4 0.5 5.8 5 1 1 6 6 6 3 zinc-finger-containing domain zf-C2HC_2 PF13913.6 OWF36155.1 - 0.00043 20.1 45.4 0.067 13.1 0.2 11.0 11 0 0 11 11 11 1 zinc-finger of a C2HC-type zf-BED PF02892.15 OWF36155.1 - 0.00063 19.7 48.3 0.38 10.8 0.4 8.8 3 2 7 10 10 9 3 BED zinc finger C1_2 PF03107.16 OWF36155.1 - 0.00069 19.9 53.5 0.22 11.8 3.0 10.4 4 4 3 7 7 7 1 C1 domain zf-C2H2_8 PF15909.5 OWF36155.1 - 0.0011 19.2 25.0 0.18 12.1 0.3 5.5 1 1 5 6 6 6 1 C2H2-type zinc ribbon zf-MYST PF17772.1 OWF36155.1 - 0.002 17.7 18.2 32 4.2 0.1 9.3 6 3 5 11 11 11 0 MYST family zinc finger domain ADK_lid PF05191.14 OWF36155.1 - 0.0041 17.1 41.0 2.1 8.4 0.0 8.9 6 4 3 9 9 9 3 Adenylate kinase, active site lid ZZ PF00569.17 OWF36155.1 - 0.0058 16.4 45.2 2.7 7.9 0.1 10.2 10 1 0 10 10 10 2 Zinc finger, ZZ type zf-H2C2_5 PF13909.6 OWF36155.1 - 0.028 14.2 1.8 0.18 11.6 0.5 10.1 9 2 0 9 9 9 0 C2H2-type zinc-finger domain XPA_N PF01286.18 OWF36155.1 - 0.031 14.3 41.8 9.4 6.4 0.1 10.6 11 0 0 11 11 11 0 XPA protein N-terminal C1_4 PF07975.12 OWF36155.1 - 0.049 13.9 39.2 0.57 10.5 2.5 6.8 4 2 4 8 8 8 0 TFIIH C1-like domain zf-AN1 PF01428.16 OWF36155.1 - 0.27 11.4 49.1 2.7 8.3 1.5 10.7 10 1 1 11 11 11 0 AN1-like Zinc finger Arc_trans_TRASH PF08394.10 OWF36155.1 - 0.28 11.5 28.7 16 5.9 0.2 8.9 9 2 0 9 9 9 0 Archaeal TRASH domain zf-C2H2_2 PF12756.7 OWF36155.1 - 0.37 11.2 44.9 6.1 7.2 0.6 9.0 1 1 8 9 9 8 0 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 OWF36155.1 - 0.45 10.6 29.7 15 5.7 0.2 8.7 9 2 1 10 10 9 0 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 OWF36155.1 - 0.63 9.9 18.4 2.9 7.8 0.8 7.1 6 2 3 9 9 8 0 C2H2 type zinc-finger (1 copy) Desulfoferrod_N PF06397.12 OWF36155.1 - 0.7 9.6 50.0 1.2 8.8 0.3 10.7 11 0 0 11 11 11 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_3rep PF18868.1 OWF36155.1 - 0.88 10.3 37.5 40 4.9 7.7 8.0 1 1 4 6 6 6 0 Zinc finger C2H2-type, 3 repeats zinc-ribbons_6 PF07191.12 OWF36155.1 - 2.7 8.0 37.7 1.5e+02 2.4 0.1 7.9 1 1 2 3 3 2 0 zinc-ribbons PHF5 PF03660.14 OWF36155.1 - 3 8.1 26.1 6.5 7.0 1.0 5.2 1 1 6 7 7 7 0 PHF5-like protein IBD PF10416.9 OWF36155.1 - 6.2 6.8 9.1 44 4.1 1.0 4.7 4 1 1 5 5 5 0 Transcription-initiator DNA-binding domain IBD DUF2180 PF09947.9 OWF36155.1 - 7.2 6.7 32.0 1.3 9.1 0.5 6.8 1 1 5 6 6 6 0 Uncharacterized protein conserved in archaea (DUF2180) Sec61_beta PF03911.16 OWF36156.1 - 2.7e-20 72.1 0.1 3.8e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Sec61beta family Med9 PF07544.13 OWF36158.1 - 0.14 12.3 0.8 0.23 11.6 0.8 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 OWF36158.1 - 0.16 11.8 0.6 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Septum formation initiator zf-H2C2_2 PF13465.6 OWF36159.1 - 2.1e-14 53.2 7.7 6.9e-09 35.7 1.1 4.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF36159.1 - 3.1e-13 49.4 28.9 5.3e-06 26.6 1.0 4.2 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF36159.1 - 1.9e-08 34.4 24.3 0.00038 21.0 1.0 4.2 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 OWF36159.1 - 0.0011 19.2 4.8 0.16 12.4 0.4 3.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF36159.1 - 0.002 18.4 1.7 0.002 18.4 1.7 2.8 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OWF36159.1 - 0.0026 18.0 2.3 6.9 7.1 0.3 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF36159.1 - 0.033 14.2 14.4 0.041 13.9 0.5 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OWF36159.1 - 0.41 10.8 3.4 0.84 9.7 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 OWF36159.1 - 0.68 10.6 13.9 4.5 8.0 0.3 4.1 3 1 1 4 4 4 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 OWF36159.1 - 0.82 9.4 4.7 2 8.1 0.4 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC_2 PF13913.6 OWF36159.1 - 4.8 7.2 13.7 0.5 10.3 0.7 3.1 3 0 0 3 3 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 OWF36159.1 - 5 7.5 9.7 3.2 8.1 0.9 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 OWF36159.1 - 5.2 7.6 6.8 4.7 7.8 0.1 3.1 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 OWF36160.1 - 3.7e-14 52.4 7.4 1.5e-08 34.7 0.9 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF36160.1 - 1.3e-12 47.4 31.1 5e-06 26.7 1.0 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF36160.1 - 3.5e-08 33.6 26.3 0.00028 21.5 2.4 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 OWF36160.1 - 0.003 17.9 5.8 0.12 12.8 0.8 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF36160.1 - 0.0055 17.0 4.1 1.2 9.5 0.8 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OWF36160.1 - 0.006 16.8 2.5 0.006 16.8 2.5 2.9 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OWF36160.1 - 0.011 15.7 1.2 0.011 15.7 1.2 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OWF36160.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 OWF36160.1 - 1.8 9.2 15.4 4.2 8.1 0.3 4.1 3 1 1 4 4 4 0 FOXP coiled-coil domain YchF-GTPase_C PF06071.13 OWF36161.1 - 1.8e-39 133.8 1.0 3.8e-39 132.7 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OWF36161.1 - 2.3e-22 79.2 0.0 1.4e-21 76.7 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF36161.1 - 1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 OWF36161.1 - 0.0026 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 OWF36161.1 - 0.0031 17.6 0.1 3.3 7.7 0.0 2.9 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 OWF36161.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GFRP PF06399.13 OWF36161.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Roc PF08477.13 OWF36161.1 - 0.062 13.5 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 OWF36161.1 - 0.15 12.6 0.0 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter zf-H2C2_2 PF13465.6 OWF36162.1 - 1.9e-12 47.0 27.0 3.4e-07 30.4 4.9 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF36162.1 - 1.5e-08 34.6 36.0 4.9e-05 23.6 1.6 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF36162.1 - 0.005 17.6 33.6 0.016 16.0 1.2 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF36162.1 - 0.014 15.3 20.4 0.068 13.2 5.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF36162.1 - 0.081 13.2 5.7 0.3 11.4 5.7 2.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 OWF36162.1 - 0.7 10.7 6.6 43 4.9 6.6 2.4 1 1 0 1 1 1 0 zinc-ribbon family Zn_Tnp_IS1 PF03811.13 OWF36162.1 - 2.5 7.9 7.9 0.67 9.7 1.8 2.5 2 0 0 2 2 2 0 InsA N-terminal domain MFS_1 PF07690.16 OWF36163.1 - 8.6e-22 77.5 37.6 8.2e-16 57.9 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_1 PF00018.28 OWF36164.1 - 1.9e-12 46.6 0.3 4.3e-12 45.4 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF36164.1 - 1.4e-11 44.0 0.1 3.3e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF36164.1 - 5.5e-09 35.6 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OWF36164.1 - 0.017 15.1 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 SH3 domain Sigma70_ner PF04546.13 OWF36164.1 - 0.034 14.0 0.0 0.034 14.0 0.0 5.9 2 1 2 4 4 4 0 Sigma-70, non-essential region HEAT_2 PF13646.6 OWF36165.1 - 3.1e-13 49.9 5.5 0.006 16.9 0.4 8.1 6 1 2 8 8 8 3 HEAT repeats HEAT PF02985.22 OWF36165.1 - 4e-12 45.3 27.9 0.067 13.5 0.0 10.8 11 0 0 11 11 11 4 HEAT repeat Adaptin_N PF01602.20 OWF36165.1 - 5.7e-05 21.9 7.3 1.9 6.9 0.4 4.9 4 1 0 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.7 OWF36165.1 - 0.001 19.1 4.1 3.8 7.5 0.0 5.4 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OWF36165.1 - 0.0018 18.7 20.1 4.1 8.0 0.2 9.1 10 0 0 10 10 10 2 HEAT-like repeat DUF3453 PF11935.8 OWF36165.1 - 0.0055 16.4 2.1 0.051 13.2 0.6 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Vac14_Fab1_bd PF12755.7 OWF36165.1 - 0.011 16.3 0.0 0.14 12.8 0.0 3.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region NopRA1 PF16201.5 OWF36165.1 - 0.015 14.9 2.5 11 5.5 0.0 4.7 5 0 0 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 DCB PF16213.5 OWF36165.1 - 0.3 10.7 3.7 1.6 8.3 0.1 3.7 2 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 TatD_DNase PF01026.21 OWF36167.1 - 5.8e-54 183.2 0.0 6.5e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 OWF36167.1 - 0.00071 19.4 0.1 0.47 10.2 0.0 3.2 1 1 1 2 2 2 2 Amidohydrolase Flexi_CP_N PF08358.10 OWF36167.1 - 0.0014 18.6 0.1 0.004 17.1 0.1 1.8 1 0 0 1 1 1 1 Carlavirus coat DUF4619 PF15398.6 OWF36168.1 - 1.1e-07 31.7 19.4 1.8e-07 31.0 19.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4619) ARGLU PF15346.6 OWF36168.1 - 0.22 11.4 26.7 1 9.3 27.2 1.8 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 p450 PF00067.22 OWF36169.1 - 4.6e-78 263.0 0.6 5.7e-78 262.7 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 SGP PF17228.2 OWF36170.1 - 1 10.3 37.8 0.17 12.8 18.5 2.1 1 1 1 2 2 2 0 Sulphur globule protein zf-RanBP PF00641.18 OWF36172.1 - 5.9e-54 179.0 71.4 4.4e-10 38.7 5.2 6.5 6 0 0 6 6 6 6 Zn-finger in Ran binding protein and others Nup153 PF08604.10 OWF36172.1 - 1e-32 113.6 29.7 2.9e-31 108.9 27.1 7.5 3 2 4 7 7 7 3 Nucleoporin Nup153-like DUF5537 PF17690.1 OWF36174.1 - 1.1e-07 31.7 0.1 1.8e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5537) NFACT-R_1 PF05670.13 OWF36175.1 - 1.7e-41 141.3 0.2 2.6e-41 140.7 0.2 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain TFX_C PF14601.6 OWF36175.1 - 0.0023 17.8 0.6 2 8.5 0.0 2.3 2 0 0 2 2 2 2 DNA_binding protein, TFX, C-term PVL_ORF50 PF07768.11 OWF36175.1 - 0.19 12.0 13.3 0.33 11.3 13.3 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family CAF-1_p150 PF11600.8 OWF36175.1 - 0.29 10.8 24.2 0.44 10.2 24.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMEM51 PF15345.6 OWF36175.1 - 1 9.2 6.8 1.6 8.5 6.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CABIT PF12736.7 OWF36176.1 - 6.4e-13 48.6 0.1 3.4e-11 43.0 0.1 2.4 1 1 0 1 1 1 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.30 OWF36176.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HSP20 PF00011.21 OWF36177.1 - 3.5e-09 36.7 0.1 6.9e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OWF36177.1 - 0.00094 18.7 0.0 0.0072 15.9 0.0 2.1 2 0 0 2 2 2 1 HSP20-like domain found in ArsA HSP20 PF00011.21 OWF36178.1 - 3.3e-09 36.8 0.1 6.9e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OWF36178.1 - 0.00094 18.7 0.0 0.0072 15.9 0.0 2.1 2 0 0 2 2 2 1 HSP20-like domain found in ArsA CABIT PF12736.7 OWF36179.1 - 1.2e-12 47.7 1.0 2e-10 40.5 1.0 3.0 1 1 0 1 1 1 1 Cell-cycle sustaining, positive selection, CABIT PF12736.7 OWF36180.1 - 1.8e-10 40.6 6.4 7e-09 35.4 2.5 3.3 2 1 0 2 2 2 1 Cell-cycle sustaining, positive selection, FRD2 PF03197.13 OWF36180.1 - 1.8 8.9 10.3 0.75 10.1 4.3 3.0 2 1 1 3 3 3 0 Bacteriophage FRD2 protein HLH PF00010.26 OWF36181.1 - 1.5e-18 66.5 0.1 1.5e-18 66.5 0.1 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain G5 PF07501.12 OWF36182.1 - 0.067 13.6 4.6 11 6.5 1.1 3.4 1 1 3 4 4 4 0 G5 domain Drf_FH1 PF06346.12 OWF36182.1 - 0.092 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 Pik1 PF11522.8 OWF36183.1 - 9.4e-20 70.3 29.6 45 4.1 0.2 26.4 1 1 19 20 20 20 6 Yeast phosphatidylinositol-4-OH kinase Pik1 Pik1 PF11522.8 OWF36184.1 - 9.4e-20 70.3 40.4 60 3.7 0.2 31.2 1 1 21 22 22 22 3 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF948 PF06103.11 OWF36184.1 - 0.00065 19.9 14.1 52 4.2 0.0 10.1 1 1 11 13 13 13 1 Bacterial protein of unknown function (DUF948) BTG PF07742.12 OWF36185.1 - 2.7e-38 130.4 0.0 8.1e-38 128.8 0.0 1.8 2 0 0 2 2 2 1 BTG family DUF812 PF05667.11 OWF36185.1 - 0.99 8.2 14.0 1.3 7.9 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GREB1 PF15782.5 OWF36185.1 - 8.9 3.3 20.8 11 3.0 20.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4819 PF16090.5 OWF36187.1 - 7.7e-22 77.2 0.1 2.8e-21 75.4 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4819) HMG_box PF00505.19 OWF36187.1 - 1.9e-16 60.2 2.9 5.2e-16 58.8 2.9 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF36187.1 - 9.1e-07 29.4 3.2 2.9e-06 27.8 3.2 2.0 1 0 0 1 1 1 1 HMG-box domain DUF4537 PF15057.6 OWF36187.1 - 0.00022 21.2 0.1 0.00065 19.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1143 PF06608.11 OWF36188.1 - 2.1e-40 138.2 3.3 2.5e-40 138.0 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) RabGAP-TBC PF00566.18 OWF36189.1 - 2.6e-26 92.6 0.5 3.9e-26 92.0 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 OWF36189.1 - 6.6e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain LPD5 PF18799.1 OWF36189.1 - 0.044 14.2 0.2 0.09 13.2 0.2 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 Sacchrp_dh_NADP PF03435.18 OWF36190.1 - 0.00046 20.4 0.4 26 5.1 0.0 4.2 2 2 1 4 4 4 1 Saccharopine dehydrogenase NADP binding domain DB PF01682.19 OWF36190.1 - 0.00053 20.2 19.6 1.3 9.3 0.8 4.6 1 1 4 5 5 5 4 DB module HemN_C PF06969.16 OWF36190.1 - 0.0031 17.6 0.0 33 4.6 0.0 5.1 2 1 5 7 7 7 1 HemN C-terminal domain EB PF01683.18 OWF36190.1 - 0.07 13.4 12.0 1.8e+04 -4.3 12.0 5.8 1 1 0 1 1 1 0 EB module DGCR6 PF07324.11 OWF36190.1 - 2.5 7.7 6.1 41 3.7 0.3 3.3 1 1 2 3 3 3 0 DiGeorge syndrome critical region 6 (DGCR6) protein PDEase_I PF00233.19 OWF36192.1 - 1.7e-65 221.1 0.1 3.8e-65 219.9 0.1 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OWF36192.1 - 2.7e-25 89.6 0.0 1.2e-18 68.0 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 OWF36192.1 - 4.5e-16 59.4 0.0 1.2e-09 38.5 0.0 3.1 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 OWF36192.1 - 2.8e-09 37.4 0.0 3e-07 30.8 0.0 3.2 2 1 0 2 2 2 1 GAF domain PDEase_I PF00233.19 OWF36193.1 - 2.5e-69 233.6 0.6 1.6e-68 231.0 0.2 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OWF36193.1 - 3.7e-25 89.1 0.0 1.2e-16 61.5 0.0 2.8 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 OWF36193.1 - 9.5e-17 61.6 0.0 3.6e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 OWF36193.1 - 8.7e-15 55.2 0.0 1.2e-10 41.8 0.0 2.7 2 0 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 OWF36193.1 - 0.0015 18.5 1.0 0.17 11.9 0.0 3.1 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor DUF5321 PF17254.2 OWF36193.1 - 4.8 6.6 11.4 8.8 5.7 11.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5321) Ribosomal_L2_C PF03947.18 OWF36194.1 - 8.3e-47 158.5 3.4 1.4e-46 157.8 3.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OWF36194.1 - 4.9e-16 58.5 0.5 4e-15 55.5 0.1 2.5 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain DEAD PF00270.29 OWF36195.1 - 3.4e-52 176.7 0.0 5.2e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF36195.1 - 3.3e-30 104.7 0.0 6.5e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF36195.1 - 0.0021 18.1 0.0 0.0046 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 OWF36196.1 - 9.6e-70 235.0 0.0 1.4e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF36196.1 - 4.9e-52 176.8 0.0 7.3e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF36196.1 - 4.5e-05 22.4 0.0 4.5e-05 22.4 0.0 2.4 2 1 0 3 3 3 1 Fungal protein kinase DUF1241 PF06840.11 OWF36196.1 - 6.5e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 OWF36196.1 - 0.0095 14.9 0.0 0.081 11.9 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Fis1_TPR_C PF14853.6 OWF36196.1 - 0.023 14.8 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Kinase-like PF14531.6 OWF36196.1 - 0.073 12.4 0.0 0.22 10.8 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Cyclin_N PF00134.23 OWF36197.1 - 4.1e-44 149.4 5.0 7.7e-41 138.8 0.5 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF36197.1 - 5.4e-31 107.1 1.6 5.4e-31 107.1 1.6 3.0 3 0 0 3 3 3 1 Cyclin, C-terminal domain Gtr1_RagA PF04670.12 OWF36198.1 - 1.7e-106 354.8 1.2 2.1e-106 354.5 1.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OWF36198.1 - 1e-09 38.6 0.0 5.1e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF36198.1 - 1e-08 35.0 0.3 2.1e-08 33.9 0.0 1.7 2 1 0 2 2 2 1 Ras family Arf PF00025.21 OWF36198.1 - 4.8e-08 32.7 0.1 1e-07 31.6 0.0 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF36198.1 - 8.5e-07 29.0 0.0 2.4e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OWF36198.1 - 0.023 14.4 0.1 0.09 12.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SecA_DEAD PF07517.14 OWF36198.1 - 0.028 13.7 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain ABC_tran PF00005.27 OWF36198.1 - 0.037 14.6 0.1 0.096 13.2 0.0 1.7 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.13 OWF36198.1 - 0.044 12.9 1.7 0.29 10.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AIG1 PF04548.16 OWF36198.1 - 0.046 13.1 2.3 0.4 10.0 2.3 2.1 1 1 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 OWF36198.1 - 0.055 13.2 0.2 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF36198.1 - 0.12 12.3 0.2 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DASH_Dam1 PF08653.10 OWF36198.1 - 4.3 7.2 5.9 0.76 9.6 0.3 2.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 Lipase_GDSL_2 PF13472.6 OWF36199.1 - 0.0019 18.7 0.0 0.0019 18.6 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Metallophos_3 PF14582.6 OWF36199.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily TrkA_N PF02254.18 OWF36201.1 - 0.00081 19.6 0.0 35 4.7 0.0 4.9 3 2 3 6 6 6 2 TrkA-N domain Collagen_bind_2 PF12904.7 OWF36201.1 - 0.021 14.8 0.1 81 3.3 0.0 4.5 2 2 1 4 4 4 0 Putative collagen-binding domain of a collagenase CSS-motif PF12792.7 OWF36201.1 - 0.044 13.3 5.1 4 6.8 0.3 3.3 1 1 2 3 3 3 0 CSS motif domain associated with EAL Kunitz_BPTI PF00014.23 OWF36203.1 - 1.5e-214 694.4 225.4 1.4e-18 66.8 8.9 14.2 14 0 0 14 14 13 13 Kunitz/Bovine pancreatic trypsin inhibitor domain Ig_3 PF13927.6 OWF36203.1 - 6.1e-38 129.3 0.4 8.1e-13 48.8 0.0 5.0 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 OWF36203.1 - 3.6e-34 116.7 0.0 2.9e-13 49.7 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF36203.1 - 8.1e-29 99.8 0.6 3e-08 33.9 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain WAP PF00095.21 OWF36203.1 - 2.3e-25 88.7 64.3 4.6e-11 42.9 13.8 13.0 16 1 0 16 16 8 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' ig PF00047.25 OWF36203.1 - 1.7e-19 69.7 0.0 3.8e-07 30.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain fn3 PF00041.21 OWF36203.1 - 1.2e-13 51.2 0.4 3.6e-13 49.7 0.2 2.0 2 0 0 2 2 1 1 Fibronectin type III domain V-set PF07686.17 OWF36203.1 - 3.7e-13 49.6 12.5 0.001 19.2 0.1 6.8 6 2 0 7 7 6 3 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF36203.1 - 5e-09 35.6 0.0 0.06 12.9 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain PLAC PF08686.11 OWF36203.1 - 1.1e-06 29.2 6.9 1.1e-06 29.2 6.9 4.3 3 0 0 3 3 1 1 PLAC (protease and lacunin) domain Pur_ac_phosph_N PF16656.5 OWF36203.1 - 6.4e-05 23.5 0.4 0.00031 21.2 0.4 2.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Receptor_2B4 PF11465.8 OWF36203.1 - 0.0054 16.9 0.1 0.079 13.2 0.0 2.8 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 zf-C2H2_4 PF13894.6 OWF36204.1 - 6e-20 70.2 35.5 6.6e-05 23.4 1.1 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF36204.1 - 4e-16 58.6 34.9 3.1e-06 27.4 2.4 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 OWF36204.1 - 9.2e-14 51.0 36.8 4.4e-05 23.7 1.4 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF36204.1 - 2.3e-07 30.9 27.2 6.7e-05 23.1 1.9 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF36204.1 - 1.2e-05 25.1 37.7 0.00063 19.7 1.8 5.2 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OWF36204.1 - 0.00011 22.4 25.4 0.0015 18.8 1.0 5.7 2 1 3 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OWF36204.1 - 0.00058 20.2 0.5 0.00058 20.2 0.5 5.3 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF36204.1 - 0.00062 20.0 8.3 0.011 16.0 1.5 2.8 2 1 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 OWF36204.1 - 0.0038 17.0 20.0 0.11 12.3 0.0 4.9 4 1 1 5 5 5 2 zinc-finger C2H2-type zf-Di19 PF05605.12 OWF36204.1 - 0.0075 16.5 26.6 0.094 13.0 6.5 4.2 2 2 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 OWF36204.1 - 0.013 16.2 12.0 0.11 13.1 4.3 3.9 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 OWF36204.1 - 0.055 13.2 0.5 0.055 13.2 0.5 5.6 7 0 0 7 7 7 0 C2H2-type zinc-finger domain Amelogenin PF02948.15 OWF36204.1 - 0.065 13.9 14.0 0.11 13.2 14.0 1.3 1 0 0 1 1 1 0 Amelogenin zf_ZIC PF18366.1 OWF36204.1 - 0.14 12.2 13.1 18 5.5 0.0 4.4 3 1 1 4 4 4 0 Zic proteins zinc finger domain Anti-TRAP PF15777.5 OWF36204.1 - 0.17 11.9 2.0 4.2 7.4 0.1 3.1 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Actin_micro PF17003.5 OWF36204.1 - 0.21 10.7 11.8 2.4 7.2 0.2 3.1 2 1 1 3 3 3 0 Putative actin-like family zf-C2H2_9 PF16293.5 OWF36204.1 - 0.36 10.7 6.0 15 5.5 0.0 3.9 3 2 1 4 4 4 0 C2H2 type zinc-finger (1 copy) HMG_box PF00505.19 OWF36205.1 - 6.5e-19 68.1 0.2 1.5e-18 67.0 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF36205.1 - 9.3e-07 29.4 0.2 2.2e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 OWF36205.1 - 0.0011 18.3 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box SmAKAP PF15127.6 OWF36205.1 - 0.16 13.2 1.2 1.2 10.4 0.7 2.5 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein zf-C2H2 PF00096.26 OWF36206.1 - 1.6e-07 31.4 41.8 0.00067 20.0 2.1 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF36206.1 - 2.4e-07 30.4 5.9 1.9e-05 24.3 0.6 5.2 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OWF36206.1 - 4.9e-06 26.7 2.0 0.0013 19.1 0.3 5.6 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF36206.1 - 0.0022 18.7 33.9 0.25 12.3 0.7 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.7 OWF36206.1 - 0.42 11.1 0.1 0.42 11.1 0.1 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type TFIIA PF03153.13 OWF36206.1 - 2.5 8.0 21.2 0.18 11.8 15.9 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Aminotran_3 PF00202.21 OWF36207.1 - 1.2e-115 386.4 0.0 1.4e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Mfp-3 PF04202.13 OWF36210.1 - 0.02 15.3 6.1 0.027 14.9 6.1 1.2 1 0 0 1 1 1 0 Foot protein 3 Mfp-3 PF04202.13 OWF36211.1 - 0.019 15.3 5.3 0.026 14.9 5.3 1.2 1 0 0 1 1 1 0 Foot protein 3 Mfp-3 PF04202.13 OWF36212.1 - 0.02 15.3 6.1 0.027 14.9 6.1 1.2 1 0 0 1 1 1 0 Foot protein 3 Mfp-3 PF04202.13 OWF36213.1 - 0.014 15.8 6.1 0.018 15.4 6.1 1.2 1 0 0 1 1 1 0 Foot protein 3 JAB PF01398.21 OWF36214.1 - 0.0018 18.2 1.8 0.0041 17.1 0.1 2.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rhamno_transf PF11316.8 OWF36214.1 - 0.012 15.0 0.1 0.012 15.0 0.1 2.7 3 0 0 3 3 3 0 Putative rhamnosyl transferase APC_rep PF18797.1 OWF36214.1 - 0.3 12.1 4.2 1.7 9.6 0.7 3.3 3 0 0 3 3 3 0 Adenomatous polyposis coli (APC) repeat Hexokinase_2 PF03727.16 OWF36215.1 - 3.3e-86 288.6 0.0 5.5e-86 287.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OWF36215.1 - 8.1e-69 231.5 0.0 1.4e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 OWF36215.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Mlp PF03304.13 OWF36215.1 - 0.13 12.5 1.0 9.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Mlp lipoprotein family APG6_N PF17675.1 OWF36216.1 - 1.5e-07 32.0 79.2 0.022 15.3 28.2 5.3 1 1 4 5 5 5 5 Apg6 coiled-coil region KASH_CCD PF14662.6 OWF36216.1 - 1e-06 28.7 79.5 0.029 14.2 15.4 5.1 1 1 3 4 4 4 3 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OWF36216.1 - 3.4e-06 27.1 84.0 0.00062 19.8 35.3 4.5 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OWF36216.1 - 4.6e-06 26.1 81.8 0.00016 21.1 20.3 4.4 1 1 3 4 4 4 4 Growth-arrest specific micro-tubule binding ADIP PF11559.8 OWF36216.1 - 0.00019 21.5 82.6 0.0022 18.1 22.6 5.4 1 1 5 6 6 6 3 Afadin- and alpha -actinin-Binding CASP_C PF08172.12 OWF36216.1 - 0.0029 17.0 6.8 0.0029 17.0 6.8 3.9 2 1 2 4 4 4 1 CASP C terminal ERM PF00769.19 OWF36216.1 - 0.0029 17.5 76.3 0.024 14.4 36.2 3.8 1 1 2 3 3 3 2 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 OWF36216.1 - 0.0029 17.8 72.8 0.17 12.1 8.6 6.1 1 1 5 6 6 6 4 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 OWF36216.1 - 0.0039 16.1 20.6 0.0039 16.1 20.6 3.8 1 1 3 4 4 4 3 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 OWF36216.1 - 0.0058 17.2 12.0 0.0058 17.2 12.0 5.6 1 1 4 6 6 6 4 Clathrin-binding domain of Huntingtin-interacting protein 1 Csm1_N PF18504.1 OWF36216.1 - 0.0069 16.7 5.1 0.0069 16.7 5.1 7.2 4 2 3 7 7 7 1 Csm1 N-terminal domain PI3K_P85_iSH2 PF16454.5 OWF36216.1 - 0.037 13.6 71.8 0.35 10.4 13.0 5.2 1 1 3 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4472 PF14739.6 OWF36216.1 - 0.049 14.4 63.3 0.075 13.8 11.4 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) YcgR PF07317.12 OWF36216.1 - 0.079 12.8 4.4 0.32 10.9 0.4 3.2 1 1 0 3 3 3 0 Flagellar regulator YcgR ATG16 PF08614.11 OWF36216.1 - 0.21 11.8 81.6 0.15 12.3 22.6 5.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OWF36216.1 - 0.38 10.8 72.8 0.22 11.6 7.4 5.4 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein SOGA PF11365.8 OWF36216.1 - 1.1 10.5 65.0 5.5 8.2 0.8 6.6 2 2 5 7 7 7 0 Protein SOGA TACC_C PF05010.14 OWF36216.1 - 1.1 9.0 63.7 0.44 10.3 20.2 4.1 1 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GOLGA2L5 PF15070.6 OWF36216.1 - 1.1 7.8 58.5 0.013 14.3 20.0 3.7 1 1 3 4 4 4 0 Putative golgin subfamily A member 2-like protein 5 SHE3 PF17078.5 OWF36216.1 - 1.4 8.5 67.0 1.1 9.0 24.4 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Lebercilin PF15619.6 OWF36216.1 - 2.4 7.8 84.3 1.7 8.3 18.3 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 OWF36216.1 - 4.1 7.6 79.6 0.15 12.2 10.3 5.5 1 1 5 6 6 6 0 BRE1 E3 ubiquitin ligase Laminin_II PF06009.12 OWF36216.1 - 5.7 6.9 53.8 0.43 10.6 12.3 4.2 1 1 3 4 4 4 0 Laminin Domain II DUF724 PF05266.14 OWF36216.1 - 8.3 6.2 65.9 0.71 9.7 10.8 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF724) DUF4028 PF13220.6 OWF36216.1 - 8.7 6.2 8.5 0.93 9.3 1.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4028) ERM PF00769.19 OWF36217.1 - 6.7e-09 35.9 75.9 7.3e-05 22.7 25.2 3.4 1 1 2 3 3 3 3 Ezrin/radixin/moesin family ADIP PF11559.8 OWF36217.1 - 0.00027 21.0 67.3 0.11 12.5 14.2 4.7 1 1 4 5 5 5 4 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 OWF36217.1 - 0.0023 18.4 81.6 0.52 10.8 21.6 4.8 1 1 3 4 4 4 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 OWF36217.1 - 0.0026 17.8 83.9 0.071 13.1 30.1 4.2 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 OWF36217.1 - 0.0076 16.1 76.9 0.23 11.3 14.7 5.0 1 1 4 5 5 5 2 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 OWF36217.1 - 0.029 14.6 68.5 1.9 8.8 15.2 5.5 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 OWF36217.1 - 0.05 13.0 78.9 1 8.7 25.3 4.7 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 OWF36217.1 - 1.3 9.8 60.7 0.34 11.7 5.1 5.4 2 1 4 6 6 6 0 Domain of unknown function (DUF4472) PI_PP_I PF18363.1 OWF36217.1 - 1.5 9.0 19.3 0.74 10.0 2.6 4.3 1 1 3 4 4 4 0 Phosphoinositide phosphatase insertion domain HIP1_clath_bdg PF16515.5 OWF36217.1 - 8.5 7.1 73.9 0.065 13.8 10.7 5.1 1 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BAAT_C PF08840.11 OWF36218.1 - 2.6e-41 141.9 0.2 8.1e-41 140.3 0.2 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 OWF36218.1 - 1.3e-32 112.5 0.0 1.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 OWF36218.1 - 0.0025 17.4 0.0 0.095 12.2 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OWF36218.1 - 0.067 12.7 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 OWF36219.1 - 7.8e-40 137.1 0.0 6.8e-39 134.0 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 OWF36219.1 - 7.1e-33 113.4 0.0 1e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 OWF36219.1 - 7.6e-07 28.9 0.0 0.083 12.4 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OWF36219.1 - 0.0016 17.9 0.0 0.0043 16.6 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lectin_C PF00059.21 OWF36220.1 - 6.5e-20 71.9 2.5 1.8e-19 70.5 2.5 1.8 1 0 0 1 1 1 1 Lectin C-type domain Cellulase PF00150.18 OWF36220.1 - 2.8e-08 33.5 3.4 5.5e-08 32.6 3.4 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_C39_2 PF13529.6 OWF36220.1 - 0.026 15.1 1.6 0.056 14.0 0.2 2.3 2 0 0 2 2 2 0 Peptidase_C39 like family Hyaluronidase_1 PF07212.11 OWF36220.1 - 0.073 12.3 0.1 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Hyaluronidase protein (HylP) BAAT_C PF08840.11 OWF36221.1 - 7.5e-43 146.9 0.0 1e-42 146.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 OWF36221.1 - 1.2e-32 112.6 0.0 1.8e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 OWF36221.1 - 1.2e-08 34.8 0.2 0.0051 16.4 0.0 3.3 2 2 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OWF36221.1 - 0.002 17.4 0.0 0.046 13.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OWF36221.1 - 0.015 14.0 0.0 0.066 11.9 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF4505 PF14956.6 OWF36221.1 - 0.053 13.3 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) Esterase_phd PF10503.9 OWF36221.1 - 0.076 12.5 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase LRR_6 PF13516.6 OWF36222.1 - 1.1e-26 90.6 19.3 0.00064 19.6 0.2 9.4 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.7 OWF36222.1 - 3.7e-12 46.3 13.8 7.6e-05 23.0 0.6 5.6 2 2 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF36222.1 - 2.8e-09 36.2 0.8 8.4 7.4 0.0 7.6 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 OWF36222.1 - 3.8e-07 29.8 14.0 0.053 13.3 1.0 5.9 2 2 3 5 5 5 5 Leucine rich repeat Glyco_hydro_18 PF00704.28 OWF36223.1 - 4.7e-98 328.8 0.2 4e-54 184.5 0.0 10.5 3 2 1 4 4 4 2 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 OWF36224.1 - 7e-32 111.4 0.1 7.6e-32 111.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GST_C_6 PF17171.4 OWF36224.1 - 0.028 14.2 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amino_oxidase PF01593.24 OWF36225.1 - 8.2e-11 41.8 0.2 1.4e-09 37.8 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Lectin_C PF00059.21 OWF36226.1 - 2.4e-15 57.2 0.2 2.9e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain Amino_oxidase PF01593.24 OWF36227.1 - 2.8e-51 175.2 0.0 3.2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF5388 PF17363.2 OWF36227.1 - 0.054 13.7 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5388) Lectin_C PF00059.21 OWF36228.1 - 2.3e-15 57.3 0.2 2.7e-15 57.0 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain zf-C2H2 PF00096.26 OWF36229.1 - 2.7e-46 153.5 96.7 4.3e-07 30.0 2.2 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF36229.1 - 4.2e-46 153.4 79.8 4.4e-08 33.2 0.2 12.6 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF36229.1 - 9.6e-41 134.9 88.0 0.00097 19.8 0.2 11.3 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF36229.1 - 8.1e-20 70.6 64.4 0.018 15.3 0.6 11.2 11 0 0 11 11 11 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF36229.1 - 6e-18 64.6 68.1 0.026 14.9 0.2 11.2 11 0 0 11 11 11 9 Zinc-finger of C2H2 type BolA PF01722.18 OWF36229.1 - 9.5e-09 35.4 13.9 0.012 15.9 0.0 7.0 3 2 1 6 6 6 3 BolA-like protein zf-C2H2_6 PF13912.6 OWF36229.1 - 1.6e-05 24.8 81.0 0.2 11.7 0.1 11.4 11 1 0 11 11 10 7 C2H2-type zinc finger zf-Di19 PF05605.12 OWF36229.1 - 1.7e-05 25.0 5.0 1.7e-05 25.0 5.0 7.1 3 1 3 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OWF36229.1 - 0.00014 21.6 58.0 0.0022 17.7 1.0 9.8 10 0 0 10 10 10 5 zinc-finger C2H2-type GAGA PF09237.11 OWF36229.1 - 0.052 13.4 13.1 2.2 8.2 0.3 5.6 5 1 2 7 7 7 0 GAGA factor zf-C2H2_8 PF15909.5 OWF36229.1 - 0.29 11.5 43.7 0.33 11.3 3.9 5.2 2 1 4 6 6 6 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 OWF36229.1 - 3.2 8.6 38.9 0.77 10.6 1.0 5.9 3 2 3 6 6 6 0 zinc-ribbon family zf-C2H2_2 PF12756.7 OWF36229.1 - 3.4 8.1 63.0 0.6 10.5 2.2 8.6 1 1 6 8 8 8 0 C2H2 type zinc-finger (2 copies) RGS PF00615.19 OWF36231.1 - 4.9e-35 120.3 1.5 9.9e-35 119.4 1.5 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain FAD_SOX PF18371.1 OWF36232.1 - 3.1e-25 88.5 1.7 4.3e-25 88.1 0.0 2.1 3 0 0 3 3 3 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Evr1_Alr PF04777.13 OWF36232.1 - 5.2e-24 84.6 1.7 3.1e-23 82.1 0.5 2.5 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 OWF36232.1 - 1e-21 76.8 0.0 7e-20 71.0 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin QSOX_Trx1 PF18108.1 OWF36232.1 - 2e-20 73.0 0.0 4.6e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 QSOX Trx-like domain Thioredoxin_2 PF13098.6 OWF36232.1 - 0.011 16.2 2.0 2 8.9 0.0 3.9 3 1 1 4 4 4 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OWF36232.1 - 0.022 15.1 7.6 0.98 9.8 0.0 4.5 3 2 1 4 4 4 0 Thioredoxin-like CheR_N PF03705.15 OWF36232.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain DUF5113 PF17140.4 OWF36232.1 - 0.1 12.4 0.8 0.32 10.8 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) eIF-5_eIF-2B PF01873.17 OWF36232.1 - 0.17 11.8 1.7 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Orf78 PF06024.12 OWF36232.1 - 3.3 8.1 5.5 13 6.2 5.5 2.0 1 1 0 1 1 1 0 Orf78 (ac78) Hormone_recep PF00104.30 OWF36233.1 - 9.9e-33 113.5 0.2 1.4e-32 113.0 0.2 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF36234.1 - 9.4e-31 106.1 15.6 1.7e-30 105.3 15.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) wnt PF00110.19 OWF36235.1 - 5.1e-120 400.7 28.3 5.9e-120 400.5 28.3 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 OWF36236.1 - 5.8e-121 403.8 24.3 6.6e-121 403.6 24.3 1.0 1 0 0 1 1 1 1 wnt family WD40 PF00400.32 OWF36237.1 - 1.2e-42 143.1 42.3 2.5e-06 28.1 0.1 12.7 12 0 0 12 12 12 8 WD domain, G-beta repeat WD40_like PF17005.5 OWF36237.1 - 3.6e-12 46.2 2.4 8.7e-05 22.0 0.7 3.5 2 1 1 3 3 3 3 WD40-like domain ANAPC4_WD40 PF12894.7 OWF36237.1 - 1.2e-09 38.3 8.6 0.00064 20.0 0.1 7.6 2 1 7 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 OWF36237.1 - 2.4e-05 24.3 0.0 7.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OWF36237.1 - 0.00059 20.1 0.0 0.0057 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Nup160 PF11715.8 OWF36237.1 - 0.002 16.9 4.0 0.026 13.2 0.2 3.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 AAA_35 PF14516.6 OWF36237.1 - 0.0047 15.8 0.1 0.0086 14.9 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain ATPase_2 PF01637.18 OWF36237.1 - 0.017 15.0 0.1 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_transf_10 PF00852.19 OWF36238.1 - 1.8e-41 141.8 0.1 2.7e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF36238.1 - 1.8e-06 28.3 0.2 3.8e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 OWF36238.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_10 PF00852.19 OWF36239.1 - 9.6e-36 123.1 0.4 1.9e-35 122.1 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF36239.1 - 5.6e-08 33.2 0.4 4.2e-07 30.4 0.0 2.5 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal Autophagy_N PF03986.13 OWF36239.1 - 0.086 12.8 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF1977 PF09320.11 OWF36240.1 - 8.5e-30 103.1 2.5 2.7e-29 101.5 2.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 OWF36240.1 - 1.5e-25 89.1 0.6 3.8e-25 87.8 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain FA_desaturase PF00487.24 OWF36240.1 - 0.0084 16.0 2.2 0.013 15.4 2.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase TPR_1 PF00515.28 OWF36240.1 - 0.011 15.6 0.1 0.25 11.2 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF36240.1 - 0.015 15.4 2.8 0.053 13.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat bVLRF1 PF18826.1 OWF36240.1 - 0.058 13.3 1.0 0.11 12.3 1.0 1.6 1 1 0 1 1 1 0 bacteroidetes VLRF1 release factor TMEM154 PF15102.6 OWF36240.1 - 0.075 12.9 0.4 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family WD40 PF00400.32 OWF36241.1 - 7.2e-09 36.2 6.7 0.0045 17.8 0.0 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF36241.1 - 0.0001 22.5 0.0 1 9.7 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 OWF36241.1 - 0.013 14.0 0.3 0.55 8.7 0.3 2.1 1 1 0 1 1 1 0 Utp8 family Ge1_WD40 PF16529.5 OWF36241.1 - 0.034 13.1 0.3 2.8 6.8 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2673 PF10880.8 OWF36241.1 - 0.071 13.2 0.1 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) RRM_1 PF00076.22 OWF36242.1 - 6.9e-12 45.0 0.1 1.3e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 OWF36242.1 - 2.4e-06 28.2 0.5 8.3e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 OWF36242.1 - 3.1e-06 27.1 1.8 3.1e-06 27.1 1.8 2.1 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 OWF36242.1 - 2.4e-05 24.2 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 OWF36242.1 - 0.0002 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 OWF36242.1 - 0.001 18.9 1.8 0.001 18.9 1.8 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OWF36242.1 - 0.0026 17.5 2.3 0.0059 16.4 2.3 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger RRM_3 PF08777.11 OWF36242.1 - 0.0049 16.9 0.3 0.01 15.9 0.1 1.7 2 0 0 2 2 2 1 RNA binding motif FYVE PF01363.21 OWF36242.1 - 0.0058 16.7 0.6 0.0058 16.7 0.6 1.8 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.6 OWF36242.1 - 0.013 16.0 0.5 0.013 16.0 0.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OWF36242.1 - 0.022 15.0 1.0 0.044 14.0 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger containing family zinc-ribbons_6 PF07191.12 OWF36242.1 - 0.52 10.3 7.9 1.2 9.2 7.9 1.6 1 0 0 1 1 1 0 zinc-ribbons HLH PF00010.26 OWF36243.1 - 2.8e-18 65.6 0.2 5.2e-18 64.8 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF36243.1 - 1.5e-08 34.7 0.3 5.1e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Hairy Orange Amnionless PF14828.6 OWF36244.1 - 0.0019 17.1 0.0 0.0019 17.1 0.0 1.8 2 1 0 2 2 2 1 Amnionless Oxidored_q2 PF00420.24 OWF36244.1 - 0.097 12.3 3.9 0.64 9.7 0.3 2.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Adeno_E3_CR2 PF02439.15 OWF36244.1 - 6.7 6.6 13.6 17 5.2 13.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EGF PF00008.27 OWF36245.1 - 4e-34 116.5 147.0 2.4e-06 27.7 8.8 10.5 10 1 0 10 10 10 8 EGF-like domain hEGF PF12661.7 OWF36245.1 - 2.3e-20 72.4 122.0 0.00073 20.1 3.6 11.6 10 1 1 11 11 11 8 Human growth factor-like EGF EGF_2 PF07974.13 OWF36245.1 - 3.4e-12 46.5 160.4 0.0058 17.0 7.8 11.0 10 0 0 10 10 10 7 EGF-like domain DSL PF01414.19 OWF36245.1 - 4.3e-12 46.1 2.1 4.3e-12 46.1 2.1 7.6 6 1 1 7 7 7 3 Delta serrate ligand cEGF PF12662.7 OWF36245.1 - 0.034 14.1 2.6 0.034 14.1 2.6 11.1 9 3 0 9 9 9 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF36245.1 - 0.086 13.1 134.7 0.15 12.4 7.5 10.1 4 3 6 10 10 10 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 OWF36246.1 - 2.9e-85 280.0 325.5 1.6e-07 31.5 9.6 19.5 19 0 0 19 19 19 18 EGF-like domain hEGF PF12661.7 OWF36246.1 - 1.3e-47 158.8 270.2 0.00011 22.7 6.8 22.1 21 0 0 21 21 21 18 Human growth factor-like EGF EGF_2 PF07974.13 OWF36246.1 - 8e-16 58.1 358.9 0.042 14.2 8.4 19.5 19 0 0 19 19 19 16 EGF-like domain FXa_inhibition PF14670.6 OWF36246.1 - 9.4e-09 35.4 278.7 0.047 14.0 13.3 19.7 4 3 15 19 19 19 11 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 OWF36246.1 - 0.013 15.7 9.4 0.013 15.7 9.4 19.4 4 4 15 19 19 19 0 Calcium-binding EGF domain Stevor PF17410.2 OWF36246.1 - 0.11 12.0 3.5 0.24 10.9 3.5 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 OWF36246.1 - 0.47 10.4 2.7 1.2 9.0 2.7 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF1180 PF06679.12 OWF36246.1 - 1.7 9.0 6.7 0.08 13.4 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) MCM PF00493.23 OWF36247.1 - 3.4e-99 330.5 0.0 4.9e-99 330.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OWF36247.1 - 2.8e-40 137.1 0.1 4.9e-40 136.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OWF36247.1 - 2.2e-25 88.9 0.1 6.6e-25 87.4 0.1 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OWF36247.1 - 6.8e-17 62.0 0.2 2.7e-16 60.0 0.2 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OWF36247.1 - 1e-08 35.3 0.0 3.9e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OWF36247.1 - 2.4e-08 33.6 0.1 1.9e-05 24.2 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OWF36247.1 - 4.8e-05 23.2 0.0 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OWF36247.1 - 0.0025 17.5 0.1 2.2 8.0 0.0 2.7 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 OWF36247.1 - 0.095 13.1 0.1 1.8 8.9 0.0 2.6 1 1 1 2 2 2 0 AAA ATPase domain Elf1 PF05129.13 OWF36247.1 - 0.16 12.0 0.6 0.58 10.2 0.6 2.0 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TPR_2 PF07719.17 OWF36247.1 - 0.74 10.1 2.6 9.2 6.7 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.21 OWF36248.1 - 1e-18 67.9 0.1 1.9e-18 67.0 0.1 1.4 1 1 0 1 1 1 1 Acyl transferase domain PH_17 PF18012.1 OWF36249.1 - 1.8e-28 98.0 0.4 3.5e-28 97.1 0.4 1.5 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 OWF36249.1 - 7.4e-19 67.9 1.6 1.3e-18 67.2 1.6 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 OWF36249.1 - 9e-11 42.2 0.1 7e-06 26.5 0.0 2.8 3 0 0 3 3 3 2 PH domain PDZ_2 PF13180.6 OWF36249.1 - 0.00017 21.8 0.1 0.00037 20.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF36249.1 - 0.0002 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 OWF36249.1 - 0.097 13.0 0.1 4.9 7.6 0.0 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain CUB PF00431.20 OWF36250.1 - 1.3e-08 35.1 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 OWF36250.1 - 7.2e-05 22.9 5.1 7.2e-05 22.9 5.1 1.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A EphA2_TM PF14575.6 OWF36250.1 - 0.024 15.5 0.3 0.024 15.5 0.3 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 OWF36250.1 - 0.027 14.4 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MLANA PF14991.6 OWF36250.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A DUF4330 PF14221.6 OWF36250.1 - 0.088 13.0 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Cadherin_C_2 PF16492.5 OWF36250.1 - 0.1 13.4 0.1 0.27 12.0 0.1 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Chordopox_A13L PF05961.11 OWF36250.1 - 0.11 12.8 0.4 0.22 11.8 0.4 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TMEMspv1-c74-12 PF11044.8 OWF36250.1 - 0.23 11.5 0.9 0.48 10.4 0.9 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PNP_phzG_C PF10590.9 OWF36252.1 - 2.2e-10 40.4 12.9 14 5.8 0.0 14.5 18 0 0 18 18 18 2 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region FtsH_ext PF06480.15 OWF36252.1 - 0.025 14.9 24.2 16 5.9 0.2 8.1 2 2 4 6 6 6 0 FtsH Extracellular SNF PF00209.18 OWF36253.1 - 2.5e-214 712.8 42.2 3.3e-214 712.4 42.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Lectin_C PF00059.21 OWF36253.1 - 5.2e-23 81.8 6.3 1.9e-11 44.7 0.4 2.7 2 0 0 2 2 2 2 Lectin C-type domain Astacin PF01400.24 OWF36254.1 - 6e-34 117.3 0.0 8.4e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 OWF36254.1 - 1.6e-24 86.6 0.0 3.3e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu EF-hand_1 PF00036.32 OWF36255.1 - 2.3e-31 105.0 11.8 3.4e-08 32.5 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF36255.1 - 1.4e-29 102.3 2.0 8.4e-15 55.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF36255.1 - 6e-27 91.2 6.0 2.2e-08 33.3 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF36255.1 - 3e-22 78.2 6.9 3.3e-08 33.2 0.2 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF36255.1 - 3.2e-20 70.7 8.2 0.00059 19.2 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF36255.1 - 3.4e-05 24.1 0.0 0.054 13.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 OWF36255.1 - 0.00047 20.4 0.3 0.027 14.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 OWF36255.1 - 0.0061 16.7 1.5 0.53 10.5 0.3 2.7 2 1 0 2 2 2 1 Dockerin type I domain EF-hand_4 PF12763.7 OWF36255.1 - 0.028 14.3 0.5 0.14 12.2 0.1 2.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OWF36255.1 - 0.1 13.5 1.8 17 6.4 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Zip PF02535.22 OWF36255.1 - 0.32 10.1 1.1 0.44 9.7 1.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AcetylCoA_hyd_C PF13336.6 OWF36256.1 - 0.0053 16.7 2.7 1 9.3 0.2 2.6 2 1 1 3 3 3 2 Acetyl-CoA hydrolase/transferase C-terminal domain CTD PF12815.7 OWF36256.1 - 0.06 13.9 0.1 5.6 7.6 0.1 2.2 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Phage-tail_2 PF09096.10 OWF36256.1 - 0.62 10.0 3.5 10 6.1 0.7 2.8 1 1 1 2 2 2 0 Baseplate structural protein, domain 2 Phage-tail_2 PF09096.10 OWF36257.1 - 0.071 13.1 23.1 3.2 7.7 0.8 5.9 1 1 5 6 6 6 0 Baseplate structural protein, domain 2 CTD PF12815.7 OWF36257.1 - 0.13 12.9 0.6 23 5.7 0.2 3.1 3 1 0 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 AcetylCoA_hyd_C PF13336.6 OWF36257.1 - 0.73 9.8 17.8 7.6 6.4 0.5 4.8 1 1 3 5 5 5 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF4383 PF14325.6 OWF36258.1 - 0.00015 22.0 65.4 0.42 10.9 2.4 7.4 1 1 5 6 6 6 6 Domain of unknown function (DUF4383) Phage-tail_2 PF09096.10 OWF36258.1 - 0.0037 17.3 48.7 0.34 10.9 1.3 9.7 1 1 8 10 10 10 5 Baseplate structural protein, domain 2 Tox-SGS PF15651.6 OWF36258.1 - 0.23 11.7 26.0 26 5.2 0.1 9.4 2 2 11 14 14 14 0 Salivary glad secreted protein domain toxin PKD_channel PF08016.12 OWF36259.1 - 2e-66 224.4 13.9 4.2e-66 223.4 13.9 1.5 1 0 0 1 1 1 1 Polycystin cation channel PLAT PF01477.23 OWF36259.1 - 2.6e-11 44.1 0.4 1.6e-10 41.5 0.3 2.3 2 0 0 2 2 2 1 PLAT/LH2 domain Lectin_C PF00059.21 OWF36259.1 - 7.6e-09 36.3 0.2 2.4e-08 34.7 0.2 1.9 1 0 0 1 1 1 1 Lectin C-type domain Death PF00531.22 OWF36259.1 - 0.006 16.7 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 Death domain DUF4229 PF14012.6 OWF36259.1 - 3 8.0 5.8 4.6 7.4 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Imm45 PF15572.6 OWF36260.1 - 0.0024 18.2 0.6 12 6.3 0.0 3.4 1 1 1 3 3 3 1 Immunity protein 45 DUF2048 PF09752.9 OWF36260.1 - 0.0075 15.4 4.0 1.6 7.7 0.3 3.4 1 1 2 3 3 3 2 Abhydrolase domain containing 18 DUF5349 PF17298.2 OWF36260.1 - 0.047 13.5 0.6 0.48 10.1 0.2 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5349) DUF4620 PF15399.6 OWF36260.1 - 0.12 12.8 12.5 4.9 7.6 0.5 4.3 1 1 5 6 6 6 0 Domain of unknown function (DUF4620) RTBV_P12 PF06361.11 OWF36260.1 - 0.14 12.6 5.8 28 5.2 0.1 4.6 1 1 5 6 6 6 0 Rice tungro bacilliform virus P12 protein Na_trans_cytopl PF11933.8 OWF36260.1 - 0.15 11.9 30.2 0.32 10.8 5.9 5.8 1 1 7 8 8 8 0 Cytoplasmic domain of voltage-gated Na+ ion channel Glucosamine_iso PF01182.20 OWF36260.1 - 0.17 11.8 1.9 2.5 7.9 0.2 3.0 1 1 2 3 3 3 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pro_racemase PF05544.11 OWF36260.1 - 0.2 10.7 6.9 0.3 10.1 0.5 2.9 1 1 2 3 3 3 0 Proline racemase Rhabdo_NV PF02484.15 OWF36260.1 - 0.52 10.5 9.8 13 6.0 0.1 4.5 1 1 5 6 6 6 0 Rhabdovirus Non-virion protein 7tm_1 PF00001.21 OWF36261.1 - 4.7e-48 163.8 14.9 6.9e-48 163.3 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF36261.1 - 1.9e-05 24.5 20.5 1.9e-05 24.5 20.5 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HLH PF00010.26 OWF36262.1 - 5.1e-17 61.6 0.7 1.1e-16 60.5 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PMBR PF09373.10 OWF36262.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein-binding repeat bZIP_2 PF07716.15 OWF36262.1 - 0.028 14.5 1.4 0.079 13.1 0.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper CREPT PF16566.5 OWF36262.1 - 0.034 14.3 1.8 0.047 13.9 1.8 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Cortex-I_coil PF09304.10 OWF36262.1 - 0.082 13.1 3.2 0.6 10.4 3.1 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DivIC PF04977.15 OWF36262.1 - 0.29 10.9 2.1 0.43 10.4 1.1 1.8 1 1 1 2 2 2 0 Septum formation initiator SH3_9 PF14604.6 OWF36263.1 - 2.2e-05 24.2 0.0 7e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain O-FucT PF10250.9 OWF36263.1 - 0.0017 18.1 0.0 0.0062 16.3 0.0 2.0 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase ATPase PF06745.13 OWF36263.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 KaiC DUF4446 PF14584.6 OWF36263.1 - 0.019 14.9 0.3 0.83 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) SH3_1 PF00018.28 OWF36263.1 - 0.028 14.0 2.8 0.075 12.7 0.1 2.5 3 0 0 3 3 3 0 SH3 domain SH3_2 PF07653.17 OWF36263.1 - 0.1 12.3 0.1 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain DivIC PF04977.15 OWF36263.1 - 0.14 12.0 0.2 0.7 9.7 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator ApoLp-III PF07464.11 OWF36263.1 - 0.46 10.6 4.1 0.95 9.5 1.9 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PDDEXK_1 PF12705.7 OWF36264.1 - 5.6e-07 29.7 0.0 8e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 OWF36264.1 - 0.083 12.1 0.2 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) zf-met PF12874.7 OWF36265.1 - 0.00031 21.0 0.8 0.00079 19.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF36265.1 - 0.00031 21.0 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF36265.1 - 0.069 13.5 0.2 0.069 13.5 0.2 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DIRP PF06584.13 OWF36265.1 - 0.27 11.4 2.6 0.3 11.3 0.6 2.1 2 1 0 2 2 2 0 DIRP HMG_box PF00505.19 OWF36266.1 - 4.7e-14 52.6 0.2 1.4e-13 51.0 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF36266.1 - 8.3e-07 29.5 0.4 3.4e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 HMG-box domain HLH PF00010.26 OWF36266.1 - 0.057 13.4 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain WD40 PF00400.32 OWF36267.1 - 8.9e-32 108.6 29.1 0.00095 19.9 0.0 10.9 10 1 0 10 10 10 7 WD domain, G-beta repeat HELP PF03451.14 OWF36267.1 - 3.4e-30 103.7 0.1 6.9e-30 102.7 0.1 1.6 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 OWF36267.1 - 4.3e-10 39.7 0.1 3.1e-05 24.2 0.0 5.3 3 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2594 PF10769.9 OWF36267.1 - 0.0026 17.8 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2594) PKcGMP_CC PF16808.5 OWF36267.1 - 0.15 11.9 0.3 0.3 11.0 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4594 PF15266.6 OWF36268.1 - 9.9e-19 68.4 27.0 9.9e-19 68.4 27.0 6.0 2 2 5 7 7 7 1 Domain of unknown function (DUF4594) PAM2 PF07145.15 OWF36268.1 - 0.007 16.0 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region SNO PF01174.19 OWF36269.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 SNO glutamine amidotransferase family InaF-motif PF15018.6 OWF36270.1 - 6e-15 54.8 3.0 7.9e-15 54.4 3.0 1.1 1 0 0 1 1 1 1 TRP-interacting helix DUF2207 PF09972.9 OWF36270.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) InaF-motif PF15018.6 OWF36271.1 - 1.3e-12 47.3 4.4 1.7e-12 47.0 4.4 1.1 1 0 0 1 1 1 1 TRP-interacting helix Uteroglobin PF01099.17 OWF36272.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Uteroglobin family Glyco_hydro_18 PF00704.28 OWF36273.1 - 4.7e-95 318.9 0.6 6.1e-95 318.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF36273.1 - 2.7e-21 75.4 11.6 1.1e-10 41.5 3.3 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 OWF36274.1 - 7.4e-184 610.6 2.8 2.2e-91 306.9 0.4 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF36274.1 - 4.7e-48 161.1 40.7 9.3e-14 51.3 5.2 4.4 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 OWF36275.1 - 1.2e-71 242.1 0.0 1.5e-71 241.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ntox27 PF15531.6 OWF36275.1 - 0.018 14.9 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 27 RNB PF00773.19 OWF36276.1 - 2.5e-99 332.7 0.0 4.1e-99 332.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OWF36276.1 - 9.7e-23 80.0 0.0 2.3e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 OWF36276.1 - 6.3e-16 58.5 0.1 1.7e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 OWF36276.1 - 0.0047 16.6 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 OWF36276.1 - 0.0088 16.2 0.0 0.64 10.2 0.0 3.2 3 0 0 3 3 3 1 Cold shock domain L_protein_N PF15518.6 OWF36276.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 L protein N-terminus Peptidase_M13_N PF05649.13 OWF36277.1 - 6.9e-124 414.4 0.0 9.5e-124 413.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF36277.1 - 7e-73 244.6 0.0 1.9e-72 243.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 HATPase_c_3 PF13589.6 OWF36279.1 - 9.2e-11 41.7 0.3 0.068 13.0 0.0 4.4 3 1 0 3 3 3 3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BRCT PF00533.26 OWF36279.1 - 0.04 14.3 1.0 0.41 11.1 0.1 3.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain YgaB PF14182.6 OWF36279.1 - 0.26 11.7 2.0 12 6.4 0.0 3.3 2 0 0 2 2 2 0 YgaB-like protein Homeodomain PF00046.29 OWF36280.1 - 9.5e-25 86.2 3.5 1.6e-24 85.5 3.5 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 OWF36280.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF36280.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain Cornifin PF02389.15 OWF36281.1 - 0.00027 21.1 21.5 0.0008 19.6 15.9 2.0 1 1 1 2 2 2 2 Cornifin (SPRR) family DUF3432 PF11914.8 OWF36281.1 - 0.0044 17.2 33.9 0.035 14.3 19.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) GED PF02212.18 OWF36281.1 - 0.021 14.9 1.9 8 6.7 0.0 3.5 1 1 2 3 3 3 0 Dynamin GTPase effector domain TGT_C1 PF14809.6 OWF36281.1 - 0.089 13.1 11.7 13 6.2 0.1 4.6 1 1 3 5 5 5 0 C1 domain of tRNA-guanine transglycosylase dimerisation DUF1411 PF07199.11 OWF36281.1 - 0.86 9.2 6.5 1.7 8.2 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) MBD_C PF14048.6 OWF36281.1 - 8.5 7.2 7.8 28 5.5 0.9 2.9 1 1 2 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 GED PF02212.18 OWF36282.1 - 0.039 14.1 0.6 4.1 7.6 0.0 2.8 2 1 1 3 3 3 0 Dynamin GTPase effector domain CEL_III_C PF18054.1 OWF36282.1 - 0.081 13.0 7.0 0.41 10.7 0.5 2.4 2 1 0 2 2 2 0 CEL-III C-terminal TGT_C1 PF14809.6 OWF36282.1 - 4 7.8 9.5 10 6.5 0.2 4.4 1 1 3 4 4 4 0 C1 domain of tRNA-guanine transglycosylase dimerisation SRP1_TIP1 PF00660.17 OWF36282.1 - 5.5 7.1 6.4 1.5 8.9 0.8 2.3 2 1 0 2 2 2 0 Seripauperin and TIP1 family Mab-21 PF03281.14 OWF36283.1 - 2e-18 66.8 0.0 3.3e-18 66.0 0.0 1.4 1 1 0 1 1 1 1 Mab-21 protein VHL PF01847.16 OWF36284.1 - 1.3e-23 82.7 0.1 2.1e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 VHL beta domain VHL_C PF17211.3 OWF36284.1 - 3.9e-12 46.0 0.1 6.6e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 VHL box domain SOCS_box PF07525.16 OWF36284.1 - 0.033 14.6 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 SOCS box IER PF05760.12 OWF36285.1 - 1.5e-22 81.3 26.3 2.4e-18 67.5 20.4 3.0 2 1 0 2 2 2 2 Immediate early response protein (IER) SPICE PF15678.5 OWF36285.1 - 0.18 11.1 16.1 0.29 10.4 16.1 1.3 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression SSF PF00474.17 OWF36286.1 - 8.9e-143 476.0 13.6 1.3e-142 475.5 13.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3290 PF11694.8 OWF36286.1 - 0.22 11.5 1.7 2.5 8.1 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4231 PF14015.6 OWF36286.1 - 8.1 7.0 10.4 11 6.6 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) zf-C4 PF00105.18 OWF36287.1 - 5e-19 68.5 15.4 5e-19 68.5 15.4 2.5 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF36287.1 - 5.6e-05 22.8 1.1 0.00033 20.3 1.1 2.2 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ank_2 PF12796.7 OWF36288.1 - 1.8e-14 54.1 1.0 1.6e-05 25.4 0.0 4.4 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF36288.1 - 3.9e-07 29.9 1.2 4 8.3 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OWF36288.1 - 5.3e-07 29.8 0.1 1 9.7 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF36288.1 - 8.2e-07 29.2 4.4 0.64 10.6 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OWF36288.1 - 0.0014 19.2 0.3 2.1 9.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OWF36289.1 - 1.2e-47 162.4 0.5 8e-46 156.4 0.5 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF36289.1 - 9.9e-45 152.9 0.0 2.1e-44 151.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 OWF36289.1 - 3.1e-24 85.0 21.8 5.7e-15 55.3 9.4 3.8 4 0 0 4 4 4 2 LIM domain PDZ_6 PF17820.1 OWF36289.1 - 2.9e-07 30.2 0.7 1.3e-06 28.2 0.2 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OWF36289.1 - 1.9e-06 28.1 0.3 5.6e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 PDZ domain Kdo PF06293.14 OWF36289.1 - 9.7e-06 25.1 0.2 1.7e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF36289.1 - 0.038 13.3 0.2 0.87 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 OWF36289.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family PDZ_2 PF13180.6 OWF36289.1 - 0.16 12.3 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain SecD_SecF PF02355.16 OWF36290.1 - 1.8e-13 50.3 43.5 0.99 8.8 0.2 12.1 1 1 17 18 18 18 18 Protein export membrane protein HNOBA PF07701.14 OWF36290.1 - 0.00018 21.0 59.0 4.5 6.6 0.2 14.5 1 1 23 24 24 24 7 Heme NO binding associated FAM101 PF15068.6 OWF36291.1 - 5.7e-18 65.6 5.1 7.9e-18 65.2 5.1 1.2 1 0 0 1 1 1 1 FAM101 family Mlo PF03094.15 OWF36292.1 - 0.0096 14.3 3.1 0.015 13.7 3.1 1.2 1 0 0 1 1 1 1 Mlo family COX14 PF14880.6 OWF36292.1 - 0.15 11.9 3.2 0.23 11.3 0.1 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c assembly BBL5 PF07289.11 OWF36293.1 - 2.1e-157 523.4 0.0 2.3e-157 523.2 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 OWF36293.1 - 5.8e-06 26.4 0.0 0.0037 17.4 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 OWF36293.1 - 7.4e-05 22.6 0.1 0.33 10.9 0.0 2.4 2 1 0 2 2 2 2 GRAM domain bPH_3 PF14470.6 OWF36293.1 - 0.00076 19.8 0.0 0.056 13.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial PH domain Voldacs PF03517.13 OWF36293.1 - 0.074 13.2 1.1 2.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling PH_TFIIH PF08567.11 OWF36293.1 - 0.084 13.2 0.1 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain DEAD PF00270.29 OWF36294.1 - 7.2e-53 178.9 0.0 6.4e-52 175.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF36294.1 - 8.3e-31 106.6 0.1 2e-29 102.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 OWF36294.1 - 0.0032 17.8 0.9 1.3 9.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain Thymidylate_kin PF02223.17 OWF36295.1 - 4.2e-17 62.4 0.0 1.2e-16 60.9 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 OWF36295.1 - 0.00032 21.2 0.2 0.016 15.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 OWF36295.1 - 0.0027 17.6 0.0 0.0096 15.8 0.0 1.8 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 OWF36295.1 - 0.0069 16.6 0.1 0.24 11.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OWF36295.1 - 0.045 14.0 0.4 0.22 11.7 0.4 2.2 1 1 0 1 1 1 0 AAA domain PAP2 PF01569.21 OWF36296.1 - 7.1e-16 58.2 5.4 1.6e-15 57.1 5.4 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OWF36296.1 - 7e-07 29.1 7.3 1.9e-06 27.7 7.3 1.7 1 0 0 1 1 1 1 PAP2 superfamily zf-C3HC4 PF00097.25 OWF36297.1 - 3.5e-09 36.4 2.3 3.5e-09 36.4 2.3 3.4 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF36297.1 - 2.5e-07 30.6 2.9 2.5e-07 30.6 2.9 2.4 2 1 0 2 2 1 1 RING-type zinc-finger zf-B_box PF00643.24 OWF36297.1 - 6.8e-06 26.1 32.0 0.0002 21.4 6.1 4.0 4 0 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 OWF36297.1 - 1.1e-05 25.3 3.5 1.1e-05 25.3 3.5 3.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF36297.1 - 4.8e-05 23.6 3.8 4.8e-05 23.6 3.8 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF36297.1 - 0.0001 22.4 7.1 0.0001 22.4 7.1 3.6 3 1 1 4 4 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF36297.1 - 0.0001 22.1 2.0 0.0001 22.1 2.0 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF36297.1 - 0.00013 21.7 5.6 0.00013 21.7 5.6 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF36297.1 - 0.0044 16.8 4.6 0.0044 16.8 4.6 3.3 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 SGL PF08450.12 OWF36297.1 - 0.016 14.8 0.0 0.25 10.9 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region C1_2 PF03107.16 OWF36297.1 - 0.028 14.7 3.1 0.028 14.7 3.1 4.2 4 1 0 4 4 4 0 C1 domain Apolipoprotein PF01442.18 OWF36297.1 - 0.89 9.4 4.3 25 4.7 4.4 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AAA_9 PF12781.7 OWF36298.1 - 0.00062 18.9 0.1 0.00091 18.4 0.1 1.4 1 1 0 1 1 1 1 ATP-binding dynein motor region AAA_9 PF12781.7 OWF36299.1 - 3e-06 26.5 0.2 6.2e-06 25.5 0.2 1.5 1 1 0 1 1 1 1 ATP-binding dynein motor region p450 PF00067.22 OWF36302.1 - 9.3e-99 331.2 0.0 1e-98 331.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MIEAP PF16026.5 OWF36303.1 - 1.8e-27 96.9 0.1 1.8e-27 96.9 0.1 2.4 3 0 0 3 3 3 1 Mitochondria-eating protein ADIP PF11559.8 OWF36303.1 - 0.0089 16.1 0.4 0.0089 16.1 0.4 3.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF4974 PF16344.5 OWF36303.1 - 0.021 14.8 0.1 0.054 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) RNA_pol_Rpb1_1 PF04997.12 OWF36304.1 - 1.3e-34 119.9 0.2 1.5e-34 119.8 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DUF4769 PF15992.5 OWF36304.1 - 0.19 11.5 0.1 0.22 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) PGDH_C PF16896.5 OWF36305.1 - 4.1e-10 39.8 0.0 1.4 8.9 0.0 5.6 1 1 5 6 6 6 6 Phosphogluconate dehydrogenase (decarboxylating) C-term Cas_VVA1548 PF09652.10 OWF36305.1 - 0.087 13.1 0.4 22 5.4 0.0 4.3 1 1 4 6 6 6 0 Putative CRISPR-associated protein (Cas_VVA1548) LacI PF00356.21 OWF36305.1 - 0.17 11.7 6.6 3 7.7 0.5 5.3 4 3 0 4 4 4 0 Bacterial regulatory proteins, lacI family M20_dimer PF07687.14 OWF36305.1 - 0.17 11.8 2.6 67 3.5 0.0 4.6 3 2 3 6 6 6 0 Peptidase dimerisation domain HTH_Tnp_4 PF13613.6 OWF36305.1 - 2.3 8.0 10.0 48 3.8 0.1 6.0 5 2 3 8 8 8 0 Helix-turn-helix of DDE superfamily endonuclease THAP PF05485.12 OWF36306.1 - 8.5e-15 55.5 0.1 1.7e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 THAP domain Amb_V_allergen PF03913.13 OWF36306.1 - 0.00066 19.6 2.1 0.0014 18.5 2.1 1.6 1 0 0 1 1 1 1 Amb V Allergen fn3 PF00041.21 OWF36307.1 - 6.7e-09 36.0 0.0 2.4e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain MMR_HSR1 PF01926.23 OWF36307.1 - 0.00029 20.9 1.3 0.012 15.6 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase Septin PF00735.18 OWF36307.1 - 0.00056 19.3 0.3 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_14 PF13173.6 OWF36307.1 - 0.0019 18.2 0.0 0.0053 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OWF36307.1 - 0.025 14.8 0.1 0.064 13.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF36307.1 - 0.086 13.4 0.1 23 5.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter FeoB_N PF02421.18 OWF36307.1 - 0.098 12.2 0.7 4.1 6.9 0.7 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 OWF36307.1 - 0.099 12.1 0.4 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NMD3 PF04981.13 OWF36308.1 - 8.7e-79 264.4 4.2 1.4e-78 263.8 4.2 1.3 1 0 0 1 1 1 1 NMD3 family DUF1221 PF06760.11 OWF36308.1 - 0.038 13.5 0.3 0.069 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) DYW_deaminase PF14432.6 OWF36308.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases LON_substr_bdg PF02190.16 OWF36308.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain NinF PF05810.12 OWF36308.1 - 0.2 11.6 3.8 0.51 10.2 0.2 3.2 4 0 0 4 4 4 0 NinF protein DZR PF12773.7 OWF36308.1 - 0.59 10.2 10.3 1.6 8.9 6.7 2.7 1 1 1 2 2 2 0 Double zinc ribbon DLH PF01738.18 OWF36309.1 - 5.9e-46 156.7 0.0 7.2e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OWF36309.1 - 0.00044 20.0 0.3 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 Putative esterase BAAT_C PF08840.11 OWF36309.1 - 0.0049 16.8 0.3 0.09 12.7 0.1 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OWF36309.1 - 0.022 14.0 0.0 0.14 11.4 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF36309.1 - 0.035 14.7 0.0 0.04 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3663 PF12404.8 OWF36309.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase Abhydrolase_1 PF00561.20 OWF36309.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 OWF36309.1 - 0.12 11.0 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 OWF36309.1 - 0.14 12.0 0.0 0.35 10.6 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OWF36309.1 - 0.2 11.1 0.8 1.5 8.2 0.2 2.0 1 1 1 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OWF36310.1 - 2e-15 56.7 0.2 2.1e-08 33.7 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OWF36310.1 - 1.3e-12 48.0 0.3 3.7e-08 33.3 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OWF36310.1 - 4.4e-07 28.9 0.3 0.016 13.9 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OWF36310.1 - 9e-07 29.7 0.0 2.4e-06 28.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OWF36310.1 - 2.2e-05 24.5 0.0 0.0048 16.8 0.0 2.4 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OWF36310.1 - 2.8e-05 23.8 0.0 0.0003 20.4 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OWF36310.1 - 3.5e-05 23.4 0.0 6.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OWF36310.1 - 9e-05 22.2 0.0 0.0047 16.5 0.0 2.4 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 OWF36310.1 - 0.00074 19.3 0.0 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein DUF818 PF05677.12 OWF36310.1 - 0.00086 18.4 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.7 OWF36310.1 - 0.0049 16.7 0.0 2 8.2 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OWF36310.1 - 0.0071 16.2 0.5 0.015 15.2 0.5 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 OWF36310.1 - 0.0076 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.13 OWF36310.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S28 PF05577.12 OWF36310.1 - 0.034 12.9 0.1 0.063 12.1 0.1 1.3 1 1 0 1 1 1 0 Serine carboxypeptidase S28 Esterase PF00756.20 OWF36310.1 - 0.096 12.3 0.0 0.39 10.3 0.0 1.9 3 0 0 3 3 3 0 Putative esterase Abhydrolase_2 PF02230.16 OWF36310.1 - 0.45 10.3 1.9 13 5.5 0.0 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Cmc1 PF08583.10 OWF36311.1 - 1.2e-11 44.5 10.7 1.6e-11 44.0 10.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 OWF36311.1 - 0.12 12.4 2.3 0.26 11.3 2.3 1.6 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Fasciclin PF02469.22 OWF36314.1 - 1e-65 219.7 0.2 1.8e-32 112.3 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain Urease_alpha PF00449.20 OWF36314.1 - 0.11 12.8 1.1 0.22 11.8 1.1 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain WBP-1 PF11669.8 OWF36315.1 - 0.0064 17.1 0.2 0.0086 16.7 0.2 1.2 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF4381 PF14316.6 OWF36315.1 - 0.0069 16.6 0.0 0.0076 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) OATP PF03137.20 OWF36315.1 - 0.061 11.6 0.0 0.072 11.4 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HemY_N PF07219.13 OWF36315.1 - 0.22 11.8 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus TNFR_16_TM PF18422.1 OWF36315.1 - 0.31 11.0 2.2 0.48 10.4 2.2 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Connexin40_C PF16791.5 OWF36315.1 - 0.42 11.9 3.2 2.3 9.5 0.1 2.1 2 0 0 2 2 2 0 Connexin 40 C-terminal domain PSP PF04046.16 OWF36315.1 - 0.89 9.5 2.7 7.4 6.5 0.1 2.3 1 1 1 2 2 2 0 PSP 7tm_2 PF00002.24 OWF36316.1 - 1.1e-56 191.9 18.3 1.6e-56 191.3 18.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 OWF36316.1 - 7.8e-21 74.5 8.8 3e-20 72.6 5.9 2.3 2 0 0 2 2 2 1 GPCR-Autoproteolysis INducing (GAIN) domain Lectin_C PF00059.21 OWF36316.1 - 2.7e-17 63.5 1.2 7.6e-17 62.0 0.4 2.2 2 0 0 2 2 2 1 Lectin C-type domain GPS PF01825.21 OWF36316.1 - 2.2e-15 56.9 3.4 5.7e-15 55.6 3.4 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Dicty_CAR PF05462.11 OWF36316.1 - 0.0087 15.2 11.8 0.014 14.5 11.8 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor HRM PF02793.22 OWF36316.1 - 0.18 12.1 10.2 0.022 15.0 4.8 2.4 2 0 0 2 2 2 0 Hormone receptor domain Chordopox_A33R PF05966.12 OWF36316.1 - 0.21 10.8 1.7 0.23 10.7 0.1 1.9 2 0 0 2 2 2 0 Chordopoxvirus A33R protein EMP70 PF02990.16 OWF36318.1 - 2.2e-216 719.6 14.9 3e-216 719.1 14.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Ribosomal_S10 PF00338.22 OWF36319.1 - 2.4e-27 95.0 0.8 2.8e-27 94.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MADF_DNA_bdg PF10545.9 OWF36320.1 - 5.1e-06 26.7 0.1 9e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like YL1 PF05764.13 OWF36321.1 - 4.6e-40 138.3 33.9 6.4e-40 137.8 33.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 OWF36321.1 - 1.1e-10 41.1 1.7 2e-10 40.3 1.7 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-RING_5 PF14634.6 OWF36323.1 - 9.5 6.3 10.7 46 4.1 0.2 3.9 1 1 1 2 2 2 0 zinc-RING finger domain SNF2_N PF00176.23 OWF36325.1 - 2.9e-100 335.4 0.2 4.2e-100 334.9 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF36325.1 - 3.8e-07 30.4 0.0 1.1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 OWF36325.1 - 0.00011 22.2 6.0 0.00011 22.2 6.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger PHD PF00628.29 OWF36325.1 - 0.00013 21.7 6.9 0.00013 21.7 6.9 3.0 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 OWF36325.1 - 0.0013 19.0 9.6 0.0013 19.0 9.6 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 OWF36325.1 - 0.0059 16.5 8.7 0.0059 16.5 8.7 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF36325.1 - 1.4 8.8 16.6 0.026 14.4 5.0 3.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF36325.1 - 5.3 7.1 23.6 0.012 15.6 9.5 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Myosin_head PF00063.21 OWF36327.1 - 2.8e-226 752.9 2.6 2.8e-226 752.9 2.6 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.5 OWF36327.1 - 6.8e-42 141.4 3.3 5.5e-41 138.5 0.1 3.2 3 0 0 3 3 3 1 Myosin VI cargo binding domain Myosin_N PF02736.19 OWF36327.1 - 7.1e-05 22.6 0.4 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 OWF36327.1 - 0.065 13.6 2.1 0.44 10.9 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OWF36327.1 - 0.086 13.1 0.1 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 OWF36327.1 - 0.17 11.9 3.1 0.39 10.8 3.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SGT1 PF07093.11 OWF36327.1 - 1.4 7.3 21.6 2.2 6.6 21.6 1.2 1 0 0 1 1 1 0 SGT1 protein MMR1 PF08505.10 OWF36327.1 - 2.4 8.4 14.9 4.8 7.4 14.9 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GST_N_4 PF17172.4 OWF36328.1 - 1.6e-30 105.8 0.0 2.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF36328.1 - 5.3e-12 45.3 0.0 8.9e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF36328.1 - 2.6e-07 31.0 0.0 4.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 OWF36328.1 - 1.1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF36328.1 - 0.045 14.0 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TarH PF02203.15 OWF36328.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue GST_C_3 PF14497.6 OWF36328.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PhyH PF05721.13 OWF36329.1 - 2e-28 100.1 0.0 3.5e-28 99.3 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OWF36329.1 - 0.061 13.7 0.1 0.2 12.1 0.0 1.9 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase DBR1 PF05011.13 OWF36329.1 - 0.098 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Peptidase_M90 PF06167.12 OWF36331.1 - 0.058 13.0 0.2 0.74 9.4 0.4 2.4 2 1 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 PRK PF00485.18 OWF36332.1 - 2.6e-47 161.1 0.2 3.7e-47 160.6 0.2 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 OWF36332.1 - 3.4e-07 30.1 0.1 7.8e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 OWF36332.1 - 7.4e-05 23.3 0.2 0.00031 21.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OWF36332.1 - 0.0032 16.8 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin PF02224.18 OWF36332.1 - 0.0036 17.1 0.6 0.036 13.8 0.7 2.2 1 1 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.6 OWF36332.1 - 0.0084 16.5 5.6 1.2 9.5 5.6 2.6 1 1 0 1 1 1 1 AAA domain Tubulin PF00091.25 OWF36332.1 - 0.085 13.0 0.2 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain AAA_33 PF13671.6 OWF36332.1 - 0.098 12.8 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Kelch_1 PF01344.25 OWF36333.1 - 1.3e-43 146.3 2.0 2.2e-11 43.2 0.0 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OWF36333.1 - 6.7e-31 105.5 0.9 4.3e-09 36.3 0.0 5.7 3 1 3 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OWF36333.1 - 1e-19 70.3 6.0 2.2e-05 24.6 0.0 6.1 6 2 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF36333.1 - 3.1e-19 68.5 4.4 0.0014 18.6 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OWF36333.1 - 1.6e-18 65.8 0.8 0.00047 20.0 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 OWF36333.1 - 4.1e-18 65.1 1.6 1.2e-05 25.2 0.0 5.5 5 1 0 5 5 5 4 Galactose oxidase, central domain RHD_dimer PF16179.5 OWF36333.1 - 0.038 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Rel homology dimerisation domain Palm_thioest PF02089.15 OWF36334.1 - 2.9e-52 177.9 0.0 2.3e-31 109.5 0.0 2.1 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OWF36334.1 - 3.6e-05 23.5 0.0 7.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 OWF36334.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 OWF36334.1 - 0.027 14.0 0.0 0.85 9.1 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 2) ASC PF00858.24 OWF36335.1 - 6.5e-49 167.1 3.9 1e-48 166.5 3.9 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Methyltr_RsmB-F PF01189.17 OWF36336.1 - 2.6e-41 141.5 0.0 4.5e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OWF36336.1 - 7.8e-07 29.4 0.0 2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 OWF36336.1 - 1.3e-05 25.0 0.0 7.7e-05 22.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OWF36336.1 - 5.2e-05 22.9 0.0 0.29 10.7 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase small domain Methyltransf_25 PF13649.6 OWF36336.1 - 5.7e-05 23.7 0.6 0.0014 19.3 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF36336.1 - 0.016 14.6 0.1 0.06 12.7 0.0 1.9 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 OWF36336.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PUA PF01472.20 OWF36336.1 - 0.034 14.1 0.5 0.13 12.3 0.3 2.1 2 1 0 2 2 2 0 PUA domain HSP70 PF00012.20 OWF36337.1 - 3.8e-11 41.9 0.0 9e-11 40.7 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein Sushi_2 PF09014.10 OWF36337.1 - 0.11 12.4 2.6 3.3 7.7 0.0 4.0 4 1 0 4 4 4 0 Beta-2-glycoprotein-1 fifth domain DUF5048 PF16467.5 OWF36338.1 - 0.072 13.4 4.6 3.4 8.0 1.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5048) Lipoprotein_16 PF03923.13 OWF36338.1 - 5.8 6.5 13.7 7.1 6.2 0.3 3.0 1 1 1 3 3 3 0 Uncharacterized lipoprotein Carb_anhydrase PF00194.21 OWF36341.1 - 3e-185 613.5 0.3 4.1e-93 311.6 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase GILT PF03227.16 OWF36343.1 - 0.028 14.6 0.2 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) XK-related PF09815.9 OWF36344.1 - 3.7e-28 98.6 32.2 8.5e-28 97.4 32.2 1.5 1 1 0 1 1 1 1 XK-related protein Motilin_ghrelin PF04644.12 OWF36345.1 - 0.16 11.8 8.1 82 3.1 0.0 4.9 6 0 0 6 6 6 0 Motilin/ghrelin BEN PF10523.9 OWF36345.1 - 0.76 10.1 10.2 18 5.6 0.7 4.3 1 1 4 5 5 5 0 BEN domain DUF5582 PF17819.1 OWF36345.1 - 1.9 9.0 6.0 1.7 9.1 1.5 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5582) Tox-GHH PF15636.6 OWF36345.1 - 3.4 7.7 23.7 2.7 8.0 1.5 4.4 1 1 3 5 5 5 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin RGS PF00615.19 OWF36346.1 - 3.4e-29 101.5 2.9 3.1e-08 33.9 0.1 4.7 4 1 0 4 4 4 4 Regulator of G protein signaling domain AA_permease_2 PF13520.6 OWF36347.1 - 3.7e-47 161.1 41.1 4.6e-47 160.8 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF36347.1 - 7.2e-30 104.0 38.9 9.8e-30 103.6 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease SR-25 PF10500.9 OWF36347.1 - 0.019 14.6 2.9 0.027 14.1 2.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPR3 PF03666.13 OWF36347.1 - 0.023 13.5 1.4 0.033 13.0 1.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF829 PF05705.14 OWF36347.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) VBS PF08913.10 OWF36348.1 - 0.028 14.9 0.3 2e+02 2.4 0.0 4.5 1 1 7 8 8 8 0 Vinculin Binding Site Phytase PF02333.15 OWF36348.1 - 0.031 13.3 1.4 16 4.4 0.1 3.1 1 1 3 4 4 4 0 Phytase RepB-RCR_reg PF10723.9 OWF36348.1 - 0.36 10.8 4.5 37 4.4 0.1 4.2 1 1 3 5 5 5 0 Replication regulatory protein RepB RepB-RCR_reg PF10723.9 OWF36349.1 - 0.14 12.2 0.6 30 4.6 0.0 3.2 1 1 2 4 4 4 0 Replication regulatory protein RepB MIP PF00230.20 OWF36350.1 - 4.1e-72 242.6 5.8 4.9e-72 242.3 5.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Gaa1 PF04114.14 OWF36351.1 - 1.5e-133 446.5 0.8 3.5e-125 418.9 0.0 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component Peptidase_M28 PF04389.17 OWF36351.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Guanylate_cyc PF00211.20 OWF36352.1 - 4.2e-63 212.3 0.1 7e-63 211.6 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 OWF36352.1 - 1e-49 169.5 0.0 1.5e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 OWF36352.1 - 1.3e-37 129.6 0.0 2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF36352.1 - 3.6e-26 92.1 0.0 6.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF36352.1 - 0.00012 21.6 0.6 0.00018 21.0 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated DUF4801 PF16059.5 OWF36352.1 - 0.078 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) zf-C2H2_4 PF13894.6 OWF36353.1 - 1.1e-24 84.9 123.2 0.0038 17.9 1.1 15.9 15 1 1 16 16 16 12 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF36353.1 - 5.8e-23 80.0 130.3 1.8e-05 24.9 0.8 15.6 15 0 0 15 15 15 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF36353.1 - 9.3e-18 63.8 104.8 0.00011 22.4 0.6 15.0 15 0 0 15 15 15 8 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF36353.1 - 0.00069 19.6 1.4 0.00069 19.6 1.4 15.1 15 1 0 15 15 15 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF36353.1 - 0.0049 17.1 3.3 0.031 14.6 0.9 11.7 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OWF36353.1 - 0.017 14.9 0.2 0.017 14.9 0.2 10.0 11 1 0 11 11 11 0 C2H2-type zinc-finger domain zf-met PF12874.7 OWF36353.1 - 0.058 13.8 0.3 0.052 13.9 3.0 12.3 13 0 0 13 13 13 0 Zinc-finger of C2H2 type 7tm_1 PF00001.21 OWF36356.1 - 1.5e-22 80.2 16.1 1.9e-22 79.8 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5134 PF17197.4 OWF36356.1 - 0.071 13.0 1.8 0.22 11.4 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) DUF679 PF05078.12 OWF36356.1 - 0.38 10.7 8.6 0.29 11.1 6.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF679) Orf78 PF06024.12 OWF36356.1 - 4.3 7.7 6.0 3 8.2 0.3 3.1 2 1 1 3 3 3 0 Orf78 (ac78) FBA PF04300.13 OWF36357.1 - 5.8e-27 94.5 0.0 1.6e-26 93.1 0.0 1.8 1 0 0 1 1 1 1 F-box associated region TPR_12 PF13424.6 OWF36357.1 - 6.5e-18 64.8 4.5 3.1e-08 33.8 0.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF4062 PF13271.6 OWF36357.1 - 5.4e-16 58.7 0.1 1.7e-15 57.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) NACHT PF05729.12 OWF36357.1 - 4.7e-10 39.6 0.0 9.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 OWF36357.1 - 5.2e-10 38.9 0.2 0.059 13.3 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 OWF36357.1 - 3.8e-05 24.1 0.0 9.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OWF36357.1 - 4.8e-05 23.4 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OWF36357.1 - 0.00072 19.8 0.0 0.0075 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.17 OWF36357.1 - 0.0019 18.1 7.2 1.1 9.6 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF36357.1 - 0.004 16.9 8.6 0.23 11.3 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF36357.1 - 0.0066 15.9 1.7 0.009 15.4 0.1 2.0 3 0 0 3 3 3 1 MalT-like TPR region RsgA_GTPase PF03193.16 OWF36357.1 - 0.029 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 OWF36357.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 OWF36357.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein TPR_8 PF13181.6 OWF36357.1 - 0.079 13.2 15.5 1.1 9.6 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat KAP_NTPase PF07693.14 OWF36357.1 - 0.087 12.0 0.1 0.54 9.4 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain TPR_7 PF13176.6 OWF36357.1 - 2 8.6 8.9 4.3 7.6 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Dpy-30 PF05186.13 OWF36358.1 - 3.6e-08 33.0 0.0 5.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 OWF36358.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Sulfotransfer_1 PF00685.27 OWF36359.1 - 2.1e-45 155.3 0.2 6e-45 153.8 0.2 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36359.1 - 6.4e-06 26.7 0.0 1.4e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF36360.1 - 5.8e-44 150.6 0.1 8.3e-43 146.8 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36360.1 - 4.6e-05 23.9 0.0 7.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family SNF2_N PF00176.23 OWF36362.1 - 2.4e-61 207.4 0.0 4.4e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF36362.1 - 4e-17 62.6 0.1 1.5e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OWF36362.1 - 7.9e-10 38.4 0.3 4.5e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 OWF36362.1 - 1.7e-09 37.9 0.2 1.8e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF36362.1 - 1e-06 28.6 0.0 3.5e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OWF36362.1 - 0.00024 20.9 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 OWF36362.1 - 0.00072 18.8 0.0 0.00072 18.8 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase LIG3_BRCT PF16759.5 OWF36362.1 - 0.00074 19.8 0.7 0.0036 17.6 0.7 2.2 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain DUF2075 PF09848.9 OWF36362.1 - 0.017 14.4 0.0 0.039 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BRCT_2 PF16589.5 OWF36362.1 - 0.035 14.5 1.4 0.077 13.4 0.1 2.3 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OWF36362.1 - 0.093 13.1 0.1 0.35 11.3 0.1 2.0 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PBP1_TM PF14812.6 OWF36362.1 - 3.7 8.0 8.3 15 6.0 8.3 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vps54_N PF10475.9 OWF36363.1 - 5.3e-100 334.4 14.6 1.1e-99 333.4 14.6 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 OWF36363.1 - 7.9e-89 297.4 2.1 7.9e-89 297.4 2.1 2.4 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Utp13 PF08625.11 OWF36363.1 - 0.11 12.4 3.4 0.54 10.2 0.0 3.3 2 1 1 3 3 3 0 Utp13 specific WD40 associated domain Sec8_exocyst PF04048.14 OWF36363.1 - 0.17 11.8 4.8 0.2 11.5 1.1 3.1 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF2730 PF10805.8 OWF36363.1 - 0.81 9.8 4.8 3.2 7.9 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) SPRY PF00622.28 OWF36364.1 - 3e-28 98.4 0.0 1.1e-14 54.5 0.0 3.2 3 0 0 3 3 3 3 SPRY domain Iso_dh PF00180.20 OWF36365.1 - 1.2e-78 264.7 0.0 1.5e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PARP PF00644.20 OWF36366.1 - 3.3e-26 92.1 0.7 5.4e-19 68.6 0.1 2.8 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain BEN PF10523.9 OWF36367.1 - 3e-05 24.2 0.0 4.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 BEN domain BEN PF10523.9 OWF36369.1 - 0.0051 17.0 0.0 0.007 16.6 0.0 1.2 1 0 0 1 1 1 1 BEN domain XPG_I PF00867.18 OWF36371.1 - 4.3e-16 59.1 0.0 4.3e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 XPG I-region DHFR_1 PF00186.19 OWF36371.1 - 0.022 14.5 0.0 0.022 14.4 0.0 1.0 1 0 0 1 1 1 0 Dihydrofolate reductase KH_1 PF00013.29 OWF36372.1 - 1e-29 102.1 8.6 3.8e-15 55.5 0.2 2.5 2 0 0 2 2 2 2 KH domain TUDOR PF00567.24 OWF36372.1 - 1.9e-27 95.7 0.0 3.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain KH_4 PF13083.6 OWF36372.1 - 3.8e-06 26.7 0.2 0.0068 16.3 0.1 2.9 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 OWF36372.1 - 2.9e-05 23.8 1.5 0.059 13.2 0.0 2.7 2 1 0 2 2 2 2 KH domain KH_5 PF13184.6 OWF36372.1 - 0.00063 19.8 3.5 0.52 10.4 1.0 2.7 2 1 0 2 2 2 2 NusA-like KH domain DUF1325 PF07039.11 OWF36372.1 - 0.0017 18.5 0.2 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 SGF29 tudor-like domain Aconitase PF00330.20 OWF36373.1 - 7.3e-180 598.9 0.0 9.2e-180 598.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OWF36373.1 - 1.1e-42 145.4 0.0 9e-42 142.5 0.0 2.3 2 0 0 2 2 2 1 Aconitase C-terminal domain Mito_carr PF00153.27 OWF36374.1 - 3.7e-43 145.4 3.1 1.4e-14 53.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Kazal_2 PF07648.15 OWF36377.1 - 4e-11 42.9 23.8 9.5e-07 28.9 5.0 2.6 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF36377.1 - 3e-09 36.7 18.7 7.9e-05 22.6 5.5 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain L71 PF02448.15 OWF36377.1 - 7.4 7.1 9.2 1.1 9.7 0.1 2.9 3 0 0 3 3 3 0 L71 family Ank_2 PF12796.7 OWF36378.1 - 8.9e-29 99.9 1.0 1.4e-11 44.8 0.0 6.0 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF36378.1 - 1.8e-28 98.5 1.1 1.5e-06 28.6 0.0 8.1 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF36378.1 - 3.7e-19 66.8 4.4 0.0037 17.6 0.0 8.8 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 OWF36378.1 - 2.5e-18 65.6 5.1 0.00026 21.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OWF36378.1 - 1.1e-16 60.7 4.6 1.9e-05 24.8 0.0 6.6 5 1 1 7 7 7 4 Ankyrin repeats (many copies) DUF3447 PF11929.8 OWF36378.1 - 0.044 13.7 0.1 2.5 8.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) RVT_1 PF00078.27 OWF36379.1 - 2.8e-07 30.3 0.0 2.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_lid_8 PF17868.1 OWF36379.1 - 0.04 13.8 0.0 0.056 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA lid domain E1_DerP2_DerF2 PF02221.15 OWF36380.1 - 1.5e-20 74.0 2.6 1.7e-20 73.8 2.6 1.0 1 0 0 1 1 1 1 ML domain Gp138_N PF18352.1 OWF36380.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain E1_DerP2_DerF2 PF02221.15 OWF36381.1 - 3.1e-18 66.5 3.4 3.5e-18 66.3 3.4 1.0 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 OWF36382.1 - 6.2e-20 72.0 3.4 1.1e-19 71.2 3.4 1.4 1 0 0 1 1 1 1 ML domain TRAUB PF08164.12 OWF36382.1 - 0.098 13.2 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Gp138_N PF18352.1 OWF36382.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain Ribosomal_L15e PF00827.17 OWF36383.1 - 3.1e-95 317.3 5.3 3.5e-95 317.2 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Amidohydro_1 PF01979.20 OWF36385.1 - 6.3e-33 114.5 0.4 8.5e-33 114.1 0.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OWF36385.1 - 2.1e-12 47.3 0.9 2.8e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family MFS_5 PF05631.14 OWF36386.1 - 7.6e-78 261.9 13.9 9.9e-78 261.5 13.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OWF36386.1 - 8.9e-15 54.5 49.4 5.1e-12 45.4 29.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1218 PF06749.12 OWF36386.1 - 8.1 7.0 8.3 1.3 9.5 0.5 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1218) Methyltransf_4 PF02390.17 OWF36387.1 - 2.9e-59 199.4 0.0 3.9e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OWF36387.1 - 0.023 15.4 0.0 0.039 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OWF36387.1 - 0.089 12.3 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 OWF36387.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.7 1 1 1 2 2 2 0 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 OWF36387.1 - 0.15 12.7 0.0 0.34 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.27 OWF36388.1 - 1.2e-10 42.0 0.0 2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF36388.1 - 3.9e-05 23.6 0.0 5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Bile_Hydr_Trans PF04775.14 OWF36389.1 - 6e-26 91.0 0.0 9.5e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAAT_C PF08840.11 OWF36389.1 - 8.2e-18 65.1 0.0 1.9e-17 63.9 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OWF36389.1 - 0.052 13.1 0.0 0.19 11.2 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OWF36389.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fibrinogen_C PF00147.18 OWF36391.1 - 2.8e-81 272.5 5.9 3.3e-81 272.3 5.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4352 PF11611.8 OWF36393.1 - 0.019 15.3 0.8 0.043 14.1 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) Bromodomain PF00439.25 OWF36395.1 - 3.1e-16 59.2 0.1 7.2e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Bromodomain zf-RING_5 PF14634.6 OWF36395.1 - 0.17 11.8 11.3 0.71 9.9 11.3 2.1 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF36395.1 - 0.49 10.3 11.7 2.4 8.1 11.7 2.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF36395.1 - 1 9.3 7.0 3.5 7.6 7.0 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF36395.1 - 1.1 9.6 11.8 5.2 7.5 11.8 2.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 OWF36395.1 - 1.1 9.1 8.5 3.7 7.5 8.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF36395.1 - 1.7 8.9 11.3 0.085 13.0 4.6 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF36395.1 - 6.2 6.8 11.3 0.75 9.7 5.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF36395.1 - 6.9 6.8 10.4 28 4.8 10.4 2.2 1 0 0 1 1 1 0 RING-type zinc-finger D123 PF07065.14 OWF36397.1 - 2.6e-106 355.2 0.1 3.1e-106 355.0 0.1 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 OWF36397.1 - 0.00022 21.3 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 OWF36397.1 - 0.00092 19.1 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 Spot_14 PF07084.12 OWF36398.1 - 1.1e-31 110.0 0.1 1.5e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 CAP PF00188.26 OWF36400.1 - 8.8e-21 75.1 2.0 8.8e-21 75.1 2.0 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family BAT2_N PF07001.11 OWF36400.1 - 4.7 7.6 17.8 0.29 11.5 10.7 2.1 2 0 0 2 2 2 0 BAT2 N-terminus Gal-3-0_sulfotr PF06990.11 OWF36401.1 - 1.4e-49 169.1 3.0 1.8e-49 168.7 3.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF36401.1 - 4.4e-06 26.8 0.6 7.6e-06 26.0 0.6 1.6 1 1 0 1 1 1 1 Sulfotransferase family HtrL_YibB PF09612.10 OWF36402.1 - 2e-15 57.1 0.3 2.9e-15 56.5 0.3 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Ank_2 PF12796.7 OWF36403.1 - 3.7e-43 146.0 1.8 5.4e-16 59.0 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF36403.1 - 8.3e-30 102.8 2.5 6.9e-11 42.5 0.0 5.7 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF36403.1 - 1.9e-26 89.2 9.4 0.00027 21.2 0.0 8.1 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OWF36403.1 - 2.7e-26 91.3 5.3 8.5e-06 26.0 0.1 5.7 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF36403.1 - 3.5e-22 77.8 5.3 0.00049 20.4 0.0 6.7 6 1 0 6 6 6 5 Ankyrin repeat Radial_spoke PF04712.12 OWF36403.1 - 2.6 6.9 10.0 3.6 6.4 10.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 OWF36403.1 - 2.9 5.9 11.8 4 5.4 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OWF36403.1 - 3.7 5.6 8.5 5 5.2 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family SOCS_box PF07525.16 OWF36404.1 - 0.064 13.6 0.2 0.41 11.1 0.0 2.3 2 1 1 3 3 3 0 SOCS box Glyco_transf_11 PF01531.16 OWF36405.1 - 1.5e-38 132.7 0.4 2.6e-38 131.9 0.4 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 11 DUF4325 PF14213.6 OWF36406.1 - 0.013 15.1 1.4 3.3 7.5 0.4 2.8 1 1 1 2 2 2 0 STAS-like domain of unknown function (DUF4325) CtsR_C PF17727.1 OWF36406.1 - 0.08 13.1 1.6 3.7 7.8 0.1 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Pribosyl_synth PF14572.6 OWF36406.1 - 0.083 12.9 1.0 8.6 6.3 0.2 2.7 1 1 1 2 2 2 0 Phosphoribosyl synthetase-associated domain DUF826 PF05696.11 OWF36406.1 - 0.18 11.9 0.0 12 6.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF826) NDK PF00334.19 OWF36406.1 - 0.61 10.1 5.7 4.1 7.4 0.9 2.2 1 1 1 2 2 2 0 Nucleoside diphosphate kinase 7tm_1 PF00001.21 OWF36407.1 - 2.7e-18 66.2 26.6 3.4e-18 65.9 26.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF36407.1 - 9.7e-18 64.5 25.8 1.3e-17 64.1 25.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF36407.1 - 9.7e-05 22.1 22.3 9.7e-05 22.1 22.3 2.9 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx MBOAT PF03062.19 OWF36408.1 - 0.053 12.9 0.4 0.065 12.6 0.4 1.3 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family ToxS PF17323.2 OWF36409.1 - 0.01 15.5 2.6 7.9 6.1 0.1 3.3 1 1 3 4 4 4 0 Trans-membrane regulatory protein ToxS ClpS PF02617.17 OWF36409.1 - 0.024 14.4 24.3 4.1 7.3 0.6 5.8 1 1 4 6 6 6 0 ATP-dependent Clp protease adaptor protein ClpS HdeA PF06411.11 OWF36409.1 - 0.057 13.6 10.5 5.5 7.3 0.2 3.8 2 1 2 4 4 4 0 HdeA/HdeB family CoA_binding_2 PF13380.6 OWF36409.1 - 0.089 13.3 0.5 0.97 9.9 0.1 2.4 1 1 1 2 2 2 0 CoA binding domain FAM198 PF15051.6 OWF36409.1 - 0.12 11.3 6.0 2 7.2 0.4 3.3 1 1 3 4 4 4 0 FAM198 protein DUF1510 PF07423.11 OWF36409.1 - 0.3 11.3 4.5 28 4.9 0.1 4.2 1 1 5 6 6 6 0 Domain of unknown function (DUF1510) YfkD PF14167.6 OWF36409.1 - 0.36 10.0 3.9 0.22 10.7 1.0 1.9 1 1 1 2 2 2 0 YfkD-like protein Sema PF01403.19 OWF36409.1 - 1.8 7.3 16.2 1.9 7.2 1.7 3.2 1 1 2 3 3 3 0 Sema domain NLPC_P60 PF00877.19 OWF36409.1 - 6.1 6.9 10.3 7.9e+03 -3.1 10.3 4.3 1 1 0 1 1 1 0 NlpC/P60 family ZZ PF00569.17 OWF36410.1 - 4e-17 61.8 21.1 9.2e-10 38.2 6.3 3.2 3 0 0 3 3 3 2 Zinc finger, ZZ type ANAPC10 PF03256.16 OWF36410.1 - 2.7e-11 43.4 0.0 5.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) EF-hand_6 PF13405.6 OWF36410.1 - 0.00062 19.5 0.1 0.49 10.5 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain CUB PF00431.20 OWF36410.1 - 0.02 15.2 0.2 0.42 11.0 0.0 3.4 3 0 0 3 3 3 0 CUB domain EF-hand_1 PF00036.32 OWF36410.1 - 0.022 14.3 1.9 0.19 11.4 0.0 3.2 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.6 OWF36410.1 - 0.024 14.1 0.2 0.075 12.6 0.2 1.9 1 0 0 1 1 1 0 EF hand DUF1408 PF07193.11 OWF36410.1 - 0.033 14.3 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) EF-hand_7 PF13499.6 OWF36410.1 - 0.059 13.8 0.1 2.6 8.6 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair SapB_1 PF05184.15 OWF36411.1 - 1.4e-67 223.1 87.8 1.4e-10 40.9 0.3 14.1 13 0 0 13 13 13 10 Saposin-like type B, region 1 SapB_2 PF03489.17 OWF36411.1 - 3.1e-46 155.1 25.4 1.5e-06 28.2 0.0 11.8 11 0 0 11 11 11 10 Saposin-like type B, region 2 RPAP3_C PF13877.6 OWF36411.1 - 0.008 16.7 0.0 15 6.2 0.0 3.7 4 0 0 4 4 4 2 Potential Monad-binding region of RPAP3 Ldl_recept_a PF00057.18 OWF36412.1 - 2.2e-148 482.2 369.5 1.6e-11 44.2 9.2 20.5 21 0 0 21 21 21 18 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 OWF36412.1 - 7.6e-136 442.4 49.7 1.8e-10 41.1 0.1 25.7 25 0 0 25 25 25 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 OWF36412.1 - 1.6e-22 79.5 207.6 5.7e-09 36.1 6.6 14.7 14 0 0 14 14 14 9 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 OWF36412.1 - 2.2e-21 76.4 0.1 8.4e-05 22.0 0.0 8.6 6 4 0 6 6 6 4 Domain of unknown function (DUF5050) SGL PF08450.12 OWF36412.1 - 3.9e-13 49.6 20.7 0.16 11.5 0.2 11.6 8 4 2 11 11 11 5 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OWF36412.1 - 5.3e-09 36.2 1.1 1.5 9.0 0.0 8.9 10 0 0 10 10 10 2 Arylesterase EGF_CA PF07645.15 OWF36412.1 - 2.9e-08 33.8 24.5 2.8e-06 27.4 7.7 22.2 13 5 7 21 21 21 3 Calcium-binding EGF domain cEGF PF12662.7 OWF36412.1 - 7.3e-06 25.8 2.9 7.3e-06 25.8 2.9 11.8 11 0 0 11 11 11 3 Complement Clr-like EGF-like EGF PF00008.27 OWF36412.1 - 5.8e-05 23.3 5.4 5.8e-05 23.3 5.4 17.7 18 0 0 18 18 18 6 EGF-like domain POTRA PF07244.15 OWF36412.1 - 0.19 12.3 0.0 0.53 10.9 0.0 1.7 1 0 0 1 1 1 0 Surface antigen variable number repeat Guanylate_kin PF00625.21 OWF36413.1 - 5.7e-51 172.8 0.0 9.5e-51 172.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.16 OWF36413.1 - 1.6e-13 50.2 1.4 6.7e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 L27 domain SH3_2 PF07653.17 OWF36413.1 - 1e-09 37.9 0.0 3.4e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.24 OWF36413.1 - 1.8e-09 37.8 0.9 4.2e-09 36.6 0.9 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 OWF36413.1 - 9.7e-08 31.5 0.0 2.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF36413.1 - 6.7e-05 22.7 0.2 0.00031 20.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PDZ_2 PF13180.6 OWF36413.1 - 0.002 18.4 0.1 0.0049 17.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF36413.1 - 0.0042 16.9 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain INSC_LBD PF16748.5 OWF36413.1 - 0.057 12.9 0.1 20 4.7 0.0 3.2 3 0 0 3 3 3 0 Inscuteable LGN-binding domain AraC_binding_2 PF14525.6 OWF36414.1 - 0.00012 21.8 5.8 0.00049 19.8 5.5 1.8 1 1 0 1 1 1 1 AraC-binding-like domain DCX PF03607.17 OWF36414.1 - 0.0079 16.3 6.8 14 5.9 0.1 4.9 1 1 3 4 4 4 1 Doublecortin Ribosomal_S22 PF08136.11 OWF36414.1 - 0.7 10.3 4.2 12 6.4 0.4 3.7 1 1 2 3 3 3 0 30S ribosomal protein subunit S22 family FbpC_C_terminal PF17845.1 OWF36414.1 - 1.5 9.0 13.1 3.6 7.8 2.0 3.4 1 1 1 3 3 3 0 FbpC C-terminal regulatory nucleotide binding domain RNA_pol_3_Rpc31 PF11705.8 OWF36416.1 - 2.1e-05 24.9 7.9 2.1e-05 24.9 7.9 4.4 3 2 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 OWF36416.1 - 0.00044 19.7 18.0 0.00044 19.7 18.0 3.1 3 0 0 3 3 3 2 BUD22 Nop14 PF04147.12 OWF36416.1 - 0.00056 18.3 15.3 0.00056 18.3 15.3 3.1 3 0 0 3 3 3 2 Nop14-like family CDC45 PF02724.14 OWF36416.1 - 0.0012 17.3 12.2 0.0012 17.3 12.2 4.0 3 1 1 4 4 4 1 CDC45-like protein SDA1 PF05285.12 OWF36416.1 - 0.0059 16.1 18.2 0.0059 16.1 18.2 3.8 3 1 1 4 4 4 1 SDA1 zf-HIT PF04438.16 OWF36417.1 - 9.4e-08 31.8 8.9 1.4e-07 31.3 8.9 1.3 1 0 0 1 1 1 1 HIT zinc finger PAPA-1 PF04795.12 OWF36417.1 - 8.3e-05 23.3 18.1 8.3e-05 23.3 18.1 3.3 2 2 0 2 2 2 1 PAPA-1-like conserved region Ion_trans PF00520.31 OWF36419.1 - 7.9e-29 100.6 13.7 1.2e-28 100.0 13.7 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF36419.1 - 8.3e-22 77.4 0.1 1.8e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF36419.1 - 3.9e-12 46.0 9.4 3.9e-12 46.0 9.4 1.9 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 OWF36419.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 OWF36419.1 - 0.0058 15.4 4.2 0.0058 15.4 4.2 1.5 2 0 0 2 2 2 1 Polycystin cation channel CoatB PF10389.9 OWF36420.1 - 0.041 13.7 1.0 0.06 13.2 1.0 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF2040 PF09745.9 OWF36421.1 - 3.4e-35 120.7 24.4 3.4e-35 120.7 24.4 4.3 2 1 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Ribosomal_L16 PF00252.18 OWF36423.1 - 2.6e-22 79.3 0.0 4.3e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e TIR_2 PF13676.6 OWF36425.1 - 3.4e-18 66.3 0.0 1e-17 64.8 0.0 1.8 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 OWF36425.1 - 3.5e-08 33.5 0.1 9.1e-08 32.1 0.1 1.7 2 0 0 2 2 2 1 TIR domain DUF1863 PF08937.11 OWF36425.1 - 0.0016 18.8 1.3 0.14 12.5 0.4 3.3 2 1 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) TIR-like PF10137.9 OWF36425.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF4481 PF14800.6 OWF36425.1 - 0.042 13.3 4.0 0.34 10.4 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4481) Ephrin_rec_like PF07699.13 OWF36426.1 - 0.077 12.8 2.8 0.1 12.4 2.8 1.2 1 0 0 1 1 1 0 Putative ephrin-receptor like Furin-like PF00757.20 OWF36427.1 - 2.8e-29 101.9 203.4 0.00063 19.6 10.0 15.3 1 1 13 14 14 14 13 Furin-like cysteine rich region TIR_2 PF13676.6 OWF36428.1 - 2.2e-18 67.0 0.0 6.2e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF36428.1 - 2e-07 31.0 0.0 4.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 OWF36428.1 - 0.0022 18.3 0.8 0.25 11.6 0.3 3.3 2 1 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) TIR-like PF10137.9 OWF36428.1 - 0.0061 16.5 0.2 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Predicted nucleotide-binding protein containing TIR-like domain DUF4481 PF14800.6 OWF36428.1 - 0.068 12.6 0.1 0.17 11.3 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4481) DUF3724 PF12521.8 OWF36429.1 - 0.0059 16.4 19.4 4.2 7.5 0.0 8.5 10 0 0 10 10 10 2 Protein of unknown function (DUF3724) CSF-1 PF05337.11 OWF36429.1 - 0.018 15.1 3.0 46 4.1 0.0 5.1 1 1 4 5 5 5 0 Macrophage colony stimulating factor-1 (CSF-1) PBP_dimer PF03717.15 OWF36429.1 - 0.095 13.0 0.6 15 5.9 0.0 3.2 2 1 1 3 3 3 0 Penicillin-binding Protein dimerisation domain Aconitase_C PF00694.19 OWF36429.1 - 0.78 10.1 4.2 37 4.7 0.1 3.8 1 1 2 4 4 4 0 Aconitase C-terminal domain eIF_4EBP PF05456.11 OWF36431.1 - 0.91 9.5 5.9 18 5.3 0.9 3.7 1 1 3 4 4 4 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Keratin_B2_2 PF13885.6 OWF36431.1 - 9.6 6.3 11.3 29 4.7 11.3 1.8 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein DUF4611 PF15387.6 OWF36432.1 - 0.02 15.1 1.3 0.032 14.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GCIP PF13324.6 OWF36432.1 - 0.27 10.8 5.4 0.35 10.4 5.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 OWF36432.1 - 0.36 11.3 8.5 0.62 10.5 8.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NUT PF12881.7 OWF36432.1 - 0.4 9.0 1.8 0.54 8.6 1.8 1.1 1 0 0 1 1 1 0 NUT protein DNA_pol_phi PF04931.13 OWF36432.1 - 2.7 6.0 6.8 3 5.8 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OWF36432.1 - 3.9 6.7 10.5 4.7 6.4 10.5 1.1 1 0 0 1 1 1 0 NOA36 protein TMV_coat PF00721.21 OWF36436.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Virus coat protein (TMV like) VWA PF00092.28 OWF36438.1 - 2e-41 142.1 5.3 1.7e-35 122.8 0.5 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF36438.1 - 2.3e-11 44.3 0.1 9.9e-11 42.3 0.0 2.0 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF36438.1 - 0.00015 21.2 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 OWF36438.1 - 0.007 16.3 0.0 0.028 14.3 0.0 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain 7tm_1 PF00001.21 OWF36439.1 - 1e-18 67.7 9.1 1.2e-18 67.4 9.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.8 OWF36439.1 - 0.14 12.3 0.2 0.14 12.3 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function EVC2_like PF12297.8 OWF36439.1 - 0.18 10.4 1.0 3.9 6.1 0.0 2.7 3 0 0 3 3 3 0 Ellis van Creveld protein 2 like protein OAD_gamma PF04277.13 OWF36439.1 - 0.62 10.7 0.0 0.62 10.7 0.0 3.4 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Apt1 PF10351.9 OWF36440.1 - 0.28 10.0 3.8 0.36 9.6 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C3HC4_3 PF13920.6 OWF36440.1 - 7.3 6.5 12.1 15 5.5 12.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CCDC32 PF14989.6 OWF36441.1 - 0.097 12.7 0.2 0.097 12.7 0.2 2.3 1 1 0 2 2 2 0 Coiled-coil domain containing 32 HTH_35 PF13693.6 OWF36442.1 - 2.1e-06 27.7 0.0 14 5.8 0.0 5.7 2 2 2 5 5 5 2 Winged helix-turn-helix DNA-binding Cuticle_3 PF11018.8 OWF36442.1 - 7.4e-05 23.0 0.0 1.8 8.7 0.0 3.8 2 1 2 4 4 4 2 Pupal cuticle protein C1 DUF5377 PF17347.2 OWF36442.1 - 0.0021 18.4 8.9 1.1e+02 3.2 0.0 7.1 7 1 0 7 7 7 0 Family of unknown function (DUF5377) CooT PF10133.9 OWF36442.1 - 0.027 14.8 11.7 70 3.8 0.1 6.6 6 2 1 7 7 7 0 CO dehydrogenase accessory protein CooT Nuclease_act PF08133.11 OWF36442.1 - 0.92 9.8 36.8 1.1e+02 3.2 0.1 13.9 7 7 11 19 19 19 0 Anticodon nuclease activator family Cuticle_3 PF11018.8 OWF36443.1 - 9.6e-05 22.7 0.0 1.1 9.5 0.0 2.9 1 1 2 3 3 3 2 Pupal cuticle protein C1 UMP1 PF05348.11 OWF36443.1 - 0.0069 16.6 2.0 0.49 10.6 0.2 3.2 3 0 0 3 3 3 1 Proteasome maturation factor UMP1 DUF5377 PF17347.2 OWF36443.1 - 0.01 16.2 7.7 54 4.2 0.0 5.6 4 1 1 6 6 6 0 Family of unknown function (DUF5377) FemAB_like PF04339.12 OWF36444.1 - 0.3 10.2 3.4 1.8 7.6 0.4 2.0 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition PI-PLC-C1 PF16670.5 OWF36444.1 - 0.45 9.5 10.1 0.18 10.9 5.8 2.2 1 1 1 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent Tubulin_C PF03953.17 OWF36444.1 - 3.4 7.8 8.9 29 4.8 0.9 3.9 1 1 2 4 4 4 0 Tubulin C-terminal domain PI-PLC-C1 PF16670.5 OWF36446.1 - 0.31 10.1 10.6 0.19 10.8 4.1 2.4 1 1 1 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent FemAB_like PF04339.12 OWF36446.1 - 0.66 9.0 2.2 3.8 6.5 0.3 2.0 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition Tubulin_C PF03953.17 OWF36446.1 - 1.9 8.6 8.0 28 4.9 1.1 3.9 1 1 3 4 4 4 0 Tubulin C-terminal domain GxGYxYP_C PF14323.6 OWF36446.1 - 2.4 8.0 9.9 14 5.5 1.1 3.0 1 1 2 3 3 3 0 GxGYxYP putative glycoside hydrolase C-terminal domain LpxI_N PF17930.1 OWF36446.1 - 8.3 6.3 7.0 5.8 6.8 1.2 3.0 1 1 2 4 4 4 0 LpxI N-terminal domain PI-PLC-C1 PF16670.5 OWF36447.1 - 0.31 10.1 10.6 0.19 10.8 4.1 2.4 1 1 1 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent FemAB_like PF04339.12 OWF36447.1 - 0.66 9.0 2.2 3.8 6.5 0.3 2.0 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition Tubulin_C PF03953.17 OWF36447.1 - 1.9 8.6 8.0 28 4.9 1.1 3.9 1 1 3 4 4 4 0 Tubulin C-terminal domain GxGYxYP_C PF14323.6 OWF36447.1 - 2.4 8.0 9.9 14 5.5 1.1 3.0 1 1 2 3 3 3 0 GxGYxYP putative glycoside hydrolase C-terminal domain LpxI_N PF17930.1 OWF36447.1 - 8.3 6.3 7.0 5.8 6.8 1.2 3.0 1 1 2 4 4 4 0 LpxI N-terminal domain Eryth_link_C PF16915.5 OWF36448.1 - 0.2 11.7 2.1 1.9 8.5 0.2 2.0 1 1 1 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus Homeobox_KN PF05920.11 OWF36448.1 - 1 9.3 4.1 14 5.6 0.5 2.4 2 1 0 2 2 2 0 Homeobox KN domain Ion_trans PF00520.31 OWF36450.1 - 3.1e-36 124.9 18.7 4.5e-36 124.3 18.7 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 OWF36450.1 - 3.1e-22 78.8 0.0 6.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 OWF36450.1 - 4.6e-12 45.8 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS PF00989.25 OWF36450.1 - 2.4e-09 37.2 0.0 5.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold Ion_trans_2 PF07885.16 OWF36450.1 - 6.7e-07 29.2 9.4 6.7e-07 29.2 9.4 2.4 2 1 0 2 2 2 1 Ion channel PAS_3 PF08447.12 OWF36450.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OWF36450.1 - 0.0032 17.7 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold Cupin_2 PF07883.11 OWF36450.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Astacin PF01400.24 OWF36451.1 - 2e-35 122.2 0.0 5.3e-35 120.8 0.0 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) R3H PF01424.22 OWF36451.1 - 0.0017 18.3 0.4 0.0037 17.2 0.4 1.6 1 0 0 1 1 1 1 R3H domain DUF4573 PF15140.6 OWF36453.1 - 0.0054 16.6 0.3 0.01 15.6 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) 2OG-FeII_Oxy PF03171.20 OWF36454.1 - 0.14 12.6 1.1 5.4 7.6 0.6 2.5 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Astacin PF01400.24 OWF36455.1 - 3.2e-31 108.4 0.3 3.6e-31 108.3 0.3 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) HcyBio PF01837.16 OWF36455.1 - 0.072 11.9 0.1 0.085 11.7 0.1 1.0 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation Lipase_GDSL_2 PF13472.6 OWF36456.1 - 1.4e-08 35.3 0.0 1.7e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF36456.1 - 0.041 13.9 0.0 0.062 13.3 0.0 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Astacin PF01400.24 OWF36457.1 - 6.2e-51 172.7 0.0 8.2e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OWF36457.1 - 0.00026 20.9 0.2 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 Matrixin XPC-binding PF09280.11 OWF36457.1 - 0.014 15.1 7.7 0.027 14.2 7.7 1.4 1 0 0 1 1 1 0 XPC-binding domain DUF4953 PF16313.5 OWF36457.1 - 0.015 14.6 1.6 0.032 13.4 0.0 2.2 3 0 0 3 3 3 0 Met-zincin Reprolysin_3 PF13582.6 OWF36457.1 - 0.039 14.5 0.0 0.099 13.2 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF36457.1 - 0.047 13.8 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OWF36457.1 - 0.062 12.9 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OWF36457.1 - 0.085 11.8 0.1 0.16 10.9 0.1 1.4 1 1 0 1 1 1 0 Peptidase M66 DUF4573 PF15140.6 OWF36460.1 - 4.9e-15 55.8 5.5 5.6e-15 55.6 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Quaking_NLS PF16551.5 OWF36460.1 - 1.8 8.3 19.1 1.7e+02 2.0 0.0 8.8 10 0 0 10 10 10 0 Putative nuclear localisation signal of quaking C1q PF00386.21 OWF36461.1 - 6.6e-20 71.6 0.0 1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF36461.1 - 0.00011 22.2 0.5 0.00018 21.4 0.5 1.4 1 0 0 1 1 1 1 BclA C-terminal domain bZIP_1 PF00170.21 OWF36461.1 - 0.023 14.8 0.2 0.035 14.2 0.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor Filament PF00038.21 OWF36461.1 - 0.035 13.7 0.1 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF5082 PF16888.5 OWF36461.1 - 0.049 13.9 0.7 0.083 13.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) CREPT PF16566.5 OWF36461.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour BLOC1_2 PF10046.9 OWF36461.1 - 0.065 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 OWF36461.1 - 0.11 11.8 0.3 0.14 11.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pou PF00157.17 OWF36463.1 - 6.3e-31 106.2 0.0 1.4e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 OWF36463.1 - 6.8e-18 64.3 1.6 1.8e-17 62.9 1.6 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 OWF36463.1 - 0.00074 19.8 0.0 0.049 14.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4770 PF15994.5 OWF36463.1 - 0.025 14.8 1.4 0.043 14.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Homeobox_KN PF05920.11 OWF36463.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Tyosinase_C PF18132.1 OWF36465.1 - 0.019 15.6 1.5 0.029 15.0 0.6 1.7 2 0 0 2 2 2 0 Tyosinase C-terminal domain FAD_binding_4 PF01565.23 OWF36465.1 - 0.03 14.1 0.3 0.053 13.3 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Sulfotransfer_1 PF00685.27 OWF36467.1 - 2.6e-46 158.3 2.2 5e-45 154.1 2.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF36467.1 - 0.00045 20.7 0.0 0.013 15.9 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family Ala_racemase_N PF01168.20 OWF36468.1 - 7.1e-22 78.1 0.0 9.2e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 OWF36468.1 - 3.1e-13 50.2 0.0 5.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Collagen PF01391.18 OWF36469.1 - 0.24 11.2 35.3 0.82 9.5 35.3 1.9 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) CDC27 PF09507.10 OWF36469.1 - 1.2 8.4 16.9 1.4 8.2 16.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BolA PF01722.18 OWF36470.1 - 4.1e-12 46.2 0.0 7.1e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein adh_short_C2 PF13561.6 OWF36471.1 - 9.4e-51 172.6 0.6 1.3e-50 172.1 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF36471.1 - 4.3e-36 124.2 1.1 6e-36 123.7 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF36471.1 - 1.9e-09 37.7 0.3 2.7e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OWF36471.1 - 0.013 15.4 0.6 0.022 14.6 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OWF36471.1 - 0.015 15.6 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OWF36471.1 - 0.024 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OWF36471.1 - 0.032 14.8 0.2 0.087 13.4 0.2 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 OWF36471.1 - 0.042 13.2 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 OWF36471.1 - 0.071 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.21 OWF36471.1 - 0.13 12.3 0.3 0.29 11.2 0.3 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain T4SS-DNA_transf PF02534.14 OWF36471.1 - 0.14 10.9 0.2 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF4573 PF15140.6 OWF36472.1 - 4.4e-05 23.4 4.3 5.8e-05 22.9 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) 7TM_GPCR_Srw PF10324.9 OWF36473.1 - 3.6e-25 88.9 20.4 4.4e-25 88.6 20.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF36473.1 - 3.7e-11 42.8 18.4 5e-11 42.4 18.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF36473.1 - 0.00011 21.7 10.3 0.00011 21.7 10.3 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Kelch_1 PF01344.25 OWF36475.1 - 9.9e-78 255.5 16.3 6.3e-16 57.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF36475.1 - 1.2e-39 133.3 7.0 1.2e-08 35.0 0.0 7.0 4 2 3 7 7 7 6 Kelch motif BACK PF07707.15 OWF36475.1 - 1.7e-34 118.0 1.7 3.4e-34 117.0 0.2 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF36475.1 - 1e-29 103.0 0.3 2e-29 102.1 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 OWF36475.1 - 6.1e-29 98.9 12.2 5.2e-08 32.5 0.0 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OWF36475.1 - 2.1e-22 78.9 8.1 4.6e-05 23.3 0.0 6.7 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF36475.1 - 4.8e-19 68.2 6.9 0.0004 20.6 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Glu_cyclase_2 PF05096.12 OWF36475.1 - 0.00084 18.8 0.0 0.45 9.9 0.0 2.4 2 0 0 2 2 2 2 Glutamine cyclotransferase Kelch_5 PF13854.6 OWF36475.1 - 0.0038 17.2 11.9 0.64 10.1 0.0 5.0 6 0 0 6 6 6 2 Kelch motif TPR_1 PF00515.28 OWF36476.1 - 1.8e-65 214.3 30.6 5.1e-09 35.6 0.0 15.2 15 1 0 15 15 15 12 Tetratricopeptide repeat TPR_2 PF07719.17 OWF36476.1 - 2.2e-47 155.3 30.0 1.8e-05 24.5 0.0 14.8 15 1 0 15 15 14 10 Tetratricopeptide repeat TPR_11 PF13414.6 OWF36476.1 - 1.3e-40 136.8 19.3 1.4e-05 24.6 0.5 13.0 9 4 4 13 13 13 9 TPR repeat TPR_8 PF13181.6 OWF36476.1 - 9.2e-34 112.8 23.8 1.8e-07 30.8 0.1 12.9 14 1 0 14 14 14 7 Tetratricopeptide repeat TPR_17 PF13431.6 OWF36476.1 - 5.4e-31 104.7 24.9 0.0029 17.9 0.2 12.1 13 1 1 14 14 14 8 Tetratricopeptide repeat TPR_9 PF13371.6 OWF36476.1 - 1.4e-26 92.4 4.3 0.0006 19.9 0.0 9.3 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 OWF36476.1 - 4.6e-23 81.3 24.1 2.6e-06 27.6 0.3 9.4 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 OWF36476.1 - 1.1e-20 74.0 18.4 2.1e-05 25.1 0.1 8.7 4 3 4 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 OWF36476.1 - 9.7e-15 54.8 12.7 0.00069 20.1 0.3 7.4 6 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF36476.1 - 1.1e-11 44.6 6.1 0.012 16.4 0.0 8.6 3 3 9 12 12 12 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF36476.1 - 6.8e-10 38.3 16.0 0.0097 15.9 0.1 8.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 OWF36476.1 - 2.7e-09 37.1 21.2 0.33 11.7 0.0 9.7 12 0 0 12 12 10 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 OWF36476.1 - 1.1e-08 34.4 3.7 5.3 6.6 0.0 8.8 10 0 0 10 10 10 1 SHNi-TPR NARP1 PF12569.8 OWF36476.1 - 2e-05 23.7 8.5 0.28 10.0 0.2 4.3 3 1 0 4 4 4 2 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 OWF36476.1 - 2.9e-05 24.2 24.7 0.019 15.2 0.4 5.7 5 2 2 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OWF36476.1 - 0.00015 21.1 3.2 1.2 8.3 0.0 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF36476.1 - 0.00069 19.4 32.3 0.35 10.8 0.0 9.8 13 0 0 13 13 13 3 Tetratricopeptide repeat DUF3856 PF12968.7 OWF36476.1 - 0.00086 19.4 4.9 0.03 14.4 1.0 4.3 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 OWF36476.1 - 0.021 14.5 7.0 0.027 14.2 1.1 3.5 2 2 3 5 5 5 0 Tetratricopeptide repeat-like domain DUF627 PF04781.12 OWF36476.1 - 0.038 14.0 8.3 0.6 10.1 0.0 4.8 5 1 1 6 6 5 0 Protein of unknown function (DUF627) LAM_C PF12544.8 OWF36476.1 - 0.13 12.4 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Glypican PF01153.19 OWF36477.1 - 3.1e-171 571.0 13.7 2.2e-129 432.8 0.8 2.4 2 1 0 2 2 2 2 Glypican TetR_C_37 PF18665.1 OWF36477.1 - 0.0097 16.5 2.0 0.024 15.3 2.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain RecR PF02132.15 OWF36477.1 - 0.21 11.2 2.1 0.62 9.7 2.1 1.9 1 0 0 1 1 1 0 RecR protein MIEAP PF16026.5 OWF36478.1 - 3.7e-40 138.3 0.7 5.1e-40 137.8 0.0 1.5 2 0 0 2 2 2 1 Mitochondria-eating protein DUF3450 PF11932.8 OWF36478.1 - 0.013 14.8 1.1 0.022 14.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TRAF_BIRC3_bd PF16673.5 OWF36478.1 - 0.22 11.3 4.6 0.12 12.2 2.2 1.8 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Cut12 PF11500.8 OWF36478.1 - 5.3 7.0 8.1 0.36 10.8 2.8 1.8 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Chordopox_A15 PF05846.12 OWF36479.1 - 1.3 9.2 13.3 51 4.2 0.3 6.1 4 1 2 6 6 6 0 Chordopoxvirus A15 protein LamB_YcsF PF03746.16 OWF36479.1 - 8 6.1 10.4 20 4.8 0.3 4.0 4 0 0 4 4 4 0 LamB/YcsF family PAS_3 PF08447.12 OWF36480.1 - 7.1e-24 83.9 0.2 2.9e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 OWF36480.1 - 1.6e-18 66.8 0.1 3.3e-13 49.7 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 OWF36480.1 - 7.4e-18 64.6 0.0 2.1e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OWF36480.1 - 1.6e-05 25.1 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OWF36480.1 - 0.00031 21.0 0.0 0.033 14.5 0.0 2.5 2 0 0 2 2 2 1 PAS fold HLH PF00010.26 OWF36480.1 - 0.00075 19.4 0.6 0.0015 18.4 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NAD_synthase PF02540.17 OWF36480.1 - 0.14 11.3 0.0 6.7 5.7 0.0 2.3 2 0 0 2 2 2 0 NAD synthase ENTH PF01417.20 OWF36481.1 - 0.00016 21.7 7.6 0.52 10.4 0.4 3.3 2 1 1 3 3 3 2 ENTH domain Ribosomal_L27_C PF18471.1 OWF36481.1 - 0.012 15.1 5.2 0.18 11.2 0.3 2.3 1 1 1 2 2 2 0 Ribosomal L27 protein C-terminal domain AvrM_N PF18247.1 OWF36481.1 - 0.05 13.5 0.3 21 5.2 0.0 3.1 2 2 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain DUF3668 PF12416.8 OWF36481.1 - 0.11 12.3 3.8 5 6.9 0.4 2.3 1 1 1 2 2 2 0 Cep120 protein UspB PF10625.9 OWF36481.1 - 0.2 11.7 1.8 17 5.4 0.1 2.5 1 1 1 2 2 2 0 Universal stress protein B (UspB) RACo_linker PF17650.1 OWF36481.1 - 0.31 10.9 2.6 40 4.1 0.1 3.4 1 1 1 3 3 3 0 RACo linker region FMN_bind_2 PF04299.12 OWF36481.1 - 1.2 8.9 25.7 8.2 6.1 1.5 4.9 1 1 2 3 3 3 0 Putative FMN-binding domain DUF2441 PF10386.9 OWF36481.1 - 9.9 6.2 21.1 2.5 8.1 1.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2441) SRR PF07709.11 OWF36482.1 - 3.9e-17 59.4 12.1 93 4.1 0.0 15.5 3 2 22 25 25 25 0 Seven Residue Repeat DUF4744 PF15918.5 OWF36482.1 - 0.039 14.8 0.0 12 6.9 0.0 3.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) S1FA PF04689.13 OWF36483.1 - 0.025 14.7 0.8 0.073 13.2 0.8 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA Presenilin PF01080.17 OWF36483.1 - 6.2 5.5 5.5 0.57 8.9 0.7 1.7 2 0 0 2 2 2 0 Presenilin DUF229 PF02995.17 OWF36484.1 - 1.4e-11 43.7 0.0 1.8e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF229 PF02995.17 OWF36485.1 - 3.7e-52 177.5 3.2 4.1e-52 177.4 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF36485.1 - 0.0033 16.9 0.1 0.0075 15.7 0.0 1.6 1 1 0 1 1 1 1 Sulfatase ShK PF01549.24 OWF36486.1 - 3.8e-20 72.1 140.3 6.7e-06 26.5 5.8 10.3 10 0 0 10 10 10 8 ShK domain-like 7tm_1 PF00001.21 OWF36487.1 - 5.6e-80 268.4 8.0 5.6e-80 268.4 8.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF36487.1 - 1e-10 41.5 13.9 1.1e-07 31.5 9.6 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF36487.1 - 1.4e-05 24.9 13.3 3.3e-05 23.7 13.3 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF36487.1 - 0.0022 17.8 8.2 0.006 16.4 5.2 2.4 2 1 0 2 2 2 1 Olfactory receptor YajC PF02699.15 OWF36487.1 - 0.12 12.2 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit LytB_WW PF18342.1 OWF36488.1 - 1.4e-06 28.3 47.0 3.6 7.8 0.4 12.3 1 1 18 19 19 19 10 Endo-beta-N-acetylglucosaminidase LytB WW domain OapA PF04225.12 OWF36488.1 - 3.9e-06 26.9 23.1 0.69 10.1 0.4 6.4 1 1 4 5 5 5 4 Opacity-associated protein A LysM-like domain zinc_ribbon_11 PF11682.8 OWF36488.1 - 0.05 13.6 0.5 1.5e+02 2.3 0.0 4.2 1 1 5 6 6 6 0 Probable zinc-ribbon Peptidase_M23 PF01551.22 OWF36488.1 - 0.21 11.8 11.1 8.8 6.6 0.3 4.0 1 1 2 3 3 3 0 Peptidase family M23 CHS5_N PF16892.5 OWF36488.1 - 2 8.5 43.9 88 3.2 0.2 12.6 1 1 16 17 17 17 0 Chitin biosynthesis protein CHS5 N-terminus FERM_M PF00373.18 OWF36489.1 - 6.2e-12 46.0 0.7 1.1e-10 41.9 0.2 2.4 2 0 0 2 2 2 1 FERM central domain DUF3546 PF12066.8 OWF36489.1 - 0.033 14.4 0.3 0.12 12.6 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) Lipocalin_2 PF08212.12 OWF36489.1 - 0.063 13.2 0.1 0.51 10.3 0.0 2.4 3 0 0 3 3 3 0 Lipocalin-like domain PP2C PF00481.21 OWF36490.1 - 7.5e-81 271.5 0.0 9.5e-81 271.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 OWF36490.1 - 3.6e-19 69.0 0.1 1.7e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 OWF36490.1 - 2.7e-05 23.9 0.0 8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Fmp27_SW PF10305.9 OWF36490.1 - 0.21 12.3 0.0 0.4 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Sprouty PF05210.13 OWF36491.1 - 9.5e-31 106.3 23.7 1.6e-30 105.5 23.7 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) WH1 PF00568.23 OWF36491.1 - 1.1e-12 47.8 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 WH1 domain 7tm_1 PF00001.21 OWF36492.1 - 8e-19 68.0 19.7 9.3e-19 67.8 19.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Lung_7-TM_R PF06814.13 OWF36493.1 - 2.4e-85 286.4 14.3 3.2e-85 286.0 14.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 OWF36493.1 - 0.015 14.7 11.6 0.017 14.5 10.6 1.6 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain LptF_LptG PF03739.14 OWF36493.1 - 0.025 13.4 0.2 0.025 13.4 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Podoplanin PF05808.11 OWF36493.1 - 1.3 9.1 5.4 2.7 8.1 5.4 1.4 1 0 0 1 1 1 0 Podoplanin ADH_N_2 PF16884.5 OWF36494.1 - 2.8e-22 78.7 0.0 4.6e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OWF36494.1 - 2.3e-14 53.5 0.0 3.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF36494.1 - 1.2e-10 42.6 0.0 1.8e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Nop53 PF07767.11 OWF36495.1 - 1.9e-81 274.5 47.0 2.7e-81 274.0 47.0 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) 60KD_IMP PF02096.20 OWF36495.1 - 6.8 6.6 8.8 1.4 8.8 1.6 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein pKID PF02173.17 OWF36496.1 - 1.1e-05 24.8 205.1 42 3.7 0.2 41.0 42 0 0 42 42 42 41 pKID domain Integrase_H2C2 PF17921.1 OWF36498.1 - 2.3e-14 53.3 0.0 3.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS66_C PF13817.6 OWF36498.1 - 0.021 15.0 0.1 0.19 11.9 0.0 2.5 2 0 0 2 2 2 0 IS66 C-terminal element zf-H2C2 PF09337.10 OWF36498.1 - 0.2 11.9 0.3 4.3 7.6 0.0 2.5 2 1 0 2 2 2 0 H2C2 zinc finger EGF PF00008.27 OWF36500.1 - 2.8e-43 145.8 159.0 4.3e-06 26.9 7.7 12.8 12 0 0 12 12 12 11 EGF-like domain hEGF PF12661.7 OWF36500.1 - 1.2e-18 66.9 136.9 5e-05 23.8 1.0 13.6 13 1 0 13 13 13 10 Human growth factor-like EGF EGF_2 PF07974.13 OWF36500.1 - 2.8e-05 24.4 185.9 0.016 15.6 9.1 12.2 12 1 0 12 12 12 9 EGF-like domain EGF_3 PF12947.7 OWF36500.1 - 0.0026 17.9 21.1 0.0045 17.2 4.8 12.5 10 2 1 11 11 11 4 EGF domain EB PF01683.18 OWF36501.1 - 8.4e-10 38.8 69.6 0.015 15.5 5.3 6.5 2 2 4 6 6 6 6 EB module cEGF PF12662.7 OWF36501.1 - 0.0082 16.0 1.7 0.0082 16.0 1.7 4.4 5 0 0 5 5 5 2 Complement Clr-like EGF-like Herpes_capsid PF06112.11 OWF36501.1 - 0.029 14.4 0.4 0.029 14.4 0.4 6.8 6 1 2 8 8 8 0 Gammaherpesvirus capsid protein EphA2_TM PF14575.6 OWF36501.1 - 0.057 14.3 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 OWF36501.1 - 0.098 12.5 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM154 PF15102.6 OWF36501.1 - 0.3 11.0 0.0 0.3 11.0 0.0 3.0 3 0 0 3 3 3 0 TMEM154 protein family WD40 PF00400.32 OWF36502.1 - 3.4e-14 53.0 11.2 0.0052 17.6 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF36502.1 - 0.0004 20.6 0.0 0.3 11.4 0.0 4.1 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF36502.1 - 0.031 13.3 0.0 6.5 5.6 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_N PF14781.6 OWF36502.1 - 0.041 13.8 0.0 23 4.9 0.0 3.6 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal PD40 PF07676.12 OWF36502.1 - 0.075 13.0 0.4 6.2 6.9 0.1 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PWWP PF00855.17 OWF36503.1 - 8.8e-35 119.0 2.4 1.8e-18 66.7 0.0 4.3 4 0 0 4 4 4 2 PWWP domain SET PF00856.28 OWF36503.1 - 2.7e-16 60.4 0.1 2.7e-16 60.4 0.1 5.0 5 4 0 5 5 5 1 SET domain AWS PF17907.1 OWF36503.1 - 5.3e-16 58.4 6.4 5.3e-16 58.4 6.4 4.0 5 0 0 5 5 5 1 AWS domain PHD PF00628.29 OWF36503.1 - 1.6e-12 47.1 79.2 9.5e-06 25.4 12.7 6.5 4 2 2 6 6 6 4 PHD-finger C5HCH PF17982.1 OWF36503.1 - 2.9e-10 40.2 5.9 2.9e-10 40.2 5.9 4.8 4 0 0 4 4 4 1 NSD Cys-His rich domain HMG_box PF00505.19 OWF36503.1 - 3.5e-05 24.1 0.8 0.00023 21.5 0.0 2.8 2 0 0 2 2 2 1 HMG (high mobility group) box W2 PF02020.18 OWF36503.1 - 0.055 13.6 0.2 0.18 11.9 0.2 1.9 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon zf-HC5HC2H PF13771.6 OWF36503.1 - 2.3 8.5 75.8 0.081 13.2 1.3 7.4 3 2 3 7 7 7 0 PHD-like zinc-binding domain PP1_bind PF15276.6 OWF36505.1 - 3.8e-16 59.1 6.3 3.8e-16 59.1 6.3 13.2 5 3 7 14 14 14 1 Protein phosphatase 1 binding FHA PF00498.26 OWF36505.1 - 2.9e-11 43.6 0.7 4.9e-11 42.8 0.7 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OWF36505.1 - 1.3e-08 35.1 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain AbrB_C PF18277.1 OWF36507.1 - 0.0061 16.2 8.5 2.1 8.1 0.1 5.7 6 0 0 6 6 6 1 AbrB C-terminal domain Haemocyan_bet_s PF14830.6 OWF36507.1 - 0.0081 16.1 0.1 4.4 7.3 0.0 2.4 1 1 1 2 2 2 2 Haemocyanin beta-sandwich CYLD_phos_site PF16607.5 OWF36507.1 - 0.84 9.5 13.9 7.3 6.4 1.6 4.1 1 1 5 6 6 6 0 Phosphorylation region of CYLD, unstructured Adeno_E3A PF05248.12 OWF36507.1 - 1.4 9.0 7.6 53 3.9 0.0 4.3 1 1 3 5 5 5 0 Adenovirus E3A Ski_Sno PF02437.17 OWF36508.1 - 3.2e-36 123.3 0.1 5.8e-36 122.5 0.1 1.4 1 0 0 1 1 1 1 SKI/SNO/DAC family ABC_tran PF00005.27 OWF36509.1 - 3.7e-27 95.5 0.1 1.3e-26 93.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 OWF36509.1 - 1.3e-18 67.2 5.0 2.1e-18 66.5 5.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 OWF36509.1 - 4.2e-05 23.5 0.2 0.021 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OWF36509.1 - 6.1e-05 23.0 0.7 0.00016 21.6 0.3 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OWF36509.1 - 0.00052 20.4 0.0 0.0009 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF36509.1 - 0.00053 20.3 0.1 0.0016 18.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF36509.1 - 0.0008 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF36509.1 - 0.0011 18.7 2.1 0.024 14.4 0.5 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 OWF36509.1 - 0.0021 17.2 0.1 0.0032 16.6 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 OWF36509.1 - 0.0021 18.0 0.1 0.0039 17.1 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 OWF36509.1 - 0.0031 17.0 1.6 1.9 7.9 0.0 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 OWF36509.1 - 0.0033 17.2 0.1 0.009 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OWF36509.1 - 0.0067 17.0 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Lon_2 PF13337.6 OWF36509.1 - 0.012 14.2 0.1 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_25 PF13481.6 OWF36509.1 - 0.021 14.4 0.0 0.081 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF36509.1 - 0.024 14.6 0.2 0.048 13.6 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 OWF36509.1 - 0.036 14.5 0.1 0.087 13.2 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OWF36509.1 - 0.056 12.6 0.6 0.1 11.8 0.6 1.5 1 1 0 1 1 1 0 NB-ARC domain ANF_receptor PF01094.28 OWF36509.1 - 0.061 12.4 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Receptor family ligand binding region cobW PF02492.19 OWF36509.1 - 0.064 12.8 0.9 0.18 11.3 0.3 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OWF36509.1 - 0.066 12.9 0.4 0.17 11.6 0.2 1.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OWF36509.1 - 0.11 12.7 0.1 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 OWF36509.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OWF36509.1 - 0.17 11.8 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 OWF36509.1 - 0.2 11.4 0.7 0.54 10.0 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation I-set PF07679.16 OWF36510.1 - 9.7e-61 201.9 4.1 3.6e-17 62.2 0.0 6.3 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF36510.1 - 8.2e-54 180.2 10.0 9.9e-15 54.9 0.1 6.2 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 OWF36510.1 - 7e-41 138.3 4.1 2e-11 43.9 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 OWF36510.1 - 1.4e-33 115.1 6.1 4.8e-11 42.8 0.0 6.4 6 0 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 OWF36510.1 - 1.8e-23 82.7 16.0 5.3e-07 29.9 0.0 6.5 5 2 0 5 5 5 4 Fibronectin type III domain V-set PF07686.17 OWF36510.1 - 3.5e-16 59.3 14.7 9.1e-06 25.8 0.2 9.0 7 3 0 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF36510.1 - 1.3e-10 41.2 0.7 0.17 12.0 0.0 5.6 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 OWF36510.1 - 8.5e-09 34.8 0.0 0.00039 19.9 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 OWF36510.1 - 2.2e-08 34.2 0.8 0.046 14.0 0.0 5.1 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 OWF36510.1 - 1.5e-05 25.3 5.1 0.65 10.4 0.0 6.1 6 0 0 6 6 6 1 Immunoglobulin C1-set domain fn3_2 PF16893.5 OWF36510.1 - 4.4e-05 23.6 0.8 0.044 13.9 0.0 3.2 3 0 0 3 3 3 2 Fibronectin type III domain Receptor_2B4 PF11465.8 OWF36510.1 - 0.023 14.9 0.1 6.5 7.0 0.0 3.6 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Pollen_allerg_1 PF01357.21 OWF36510.1 - 0.032 14.3 0.3 0.1 12.6 0.3 1.9 1 0 0 1 1 1 0 Pollen allergen Cadherin-like PF12733.7 OWF36510.1 - 0.044 14.3 0.8 0.36 11.4 0.1 3.1 2 0 0 2 2 1 0 Cadherin-like beta sandwich domain DUF4576 PF15144.6 OWF36510.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Izumo-Ig PF16706.5 OWF36510.1 - 0.082 13.0 0.1 18 5.5 0.0 2.9 3 0 0 3 3 2 0 Izumo-like Immunoglobulin domain CARD PF00619.21 OWF36511.1 - 9.5e-13 48.0 0.0 2.6e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.22 OWF36511.1 - 2.9e-05 24.2 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Death domain CARD_2 PF16739.5 OWF36511.1 - 0.00097 19.1 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Caspase recruitment domain Tim44 PF04280.15 OWF36512.1 - 3.3e-05 24.0 0.0 5.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain EFP PF01132.20 OWF36512.1 - 0.021 14.8 2.4 0.035 14.1 2.4 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain Glyco_transf_10 PF00852.19 OWF36513.1 - 1.1e-44 152.3 1.0 1.7e-44 151.7 1.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF36513.1 - 1.5e-12 47.9 0.2 4.4e-12 46.4 0.2 1.9 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal RPE65 PF03055.15 OWF36515.1 - 1.1e-74 252.3 1.0 1.4e-74 252.0 1.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CUB PF00431.20 OWF36516.1 - 1.6e-27 96.0 0.7 1.9e-14 53.9 0.5 2.3 2 0 0 2 2 2 2 CUB domain KdpA PF03814.15 OWF36516.1 - 0.017 13.3 3.5 0.027 12.7 3.5 1.2 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit Pkinase PF00069.25 OWF36517.1 - 6.6e-46 156.8 0.5 3.4e-40 138.1 0.2 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF36517.1 - 2.4e-16 59.8 0.1 3.4e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF36517.1 - 0.00076 18.9 0.2 0.0015 17.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF36517.1 - 0.011 15.7 0.1 0.099 12.5 0.1 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OWF36517.1 - 0.012 15.2 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OWF36517.1 - 0.019 14.6 0.3 0.03 13.9 0.3 1.3 1 0 0 1 1 1 0 RIO1 family YcxB PF14317.6 OWF36517.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein WD40 PF00400.32 OWF36518.1 - 0.00015 22.5 0.2 0.13 13.2 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Ribosomal_S11 PF00411.19 OWF36519.1 - 1.8e-28 99.2 1.8 2.6e-28 98.6 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Edc3_linker PF16598.5 OWF36519.1 - 0.021 15.4 0.3 0.054 14.2 0.1 1.7 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 UBZ_FAAP20 PF15750.5 OWF36521.1 - 0.17 11.9 10.8 71 3.5 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-binding zinc-finger Corona_NS4 PF03905.13 OWF36521.1 - 0.28 11.3 8.5 0.44 10.6 0.7 3.7 2 1 3 5 5 5 0 Coronavirus non-structural protein NS4 HTH_Tnp_4 PF13613.6 OWF36521.1 - 10 6.0 16.6 5.6 6.8 0.2 6.0 3 2 3 7 7 7 0 Helix-turn-helix of DDE superfamily endonuclease DUF5438 PF17506.2 OWF36522.1 - 0.00074 19.8 0.2 35 4.8 0.2 9.9 1 0 0 1 1 1 1 Family of unknown function (DUF5438) DUF2963 PF11178.8 OWF36523.1 - 0.022 14.5 34.4 1.5e+02 2.2 0.0 14.2 3 2 13 17 17 17 0 Protein of unknown function (DUF2963) HA1 PF18239.1 OWF36523.1 - 4.1 7.3 41.6 28 4.7 0.2 10.2 1 1 14 15 15 15 0 Hemagglutinin I Sec1 PF00995.23 OWF36524.1 - 4.1e-13 49.4 0.0 4.6e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RhoGAP PF00620.27 OWF36525.1 - 1.4e-41 141.9 0.1 2.6e-41 140.9 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 OWF36525.1 - 1.2e-39 135.6 4.3 2e-39 134.9 4.3 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 OWF36525.1 - 6e-09 35.8 1.2 6e-09 35.8 1.2 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain COesterase PF00135.28 OWF36526.1 - 1.4e-130 436.6 0.0 1.6e-130 436.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF36526.1 - 8.5e-06 25.8 0.0 3.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold TNF PF00229.18 OWF36527.1 - 9.2e-27 93.5 0.2 1.4e-26 92.9 0.2 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family CD225 PF04505.12 OWF36528.1 - 3.8e-21 75.0 0.4 3.8e-21 75.0 0.4 1.4 2 0 0 2 2 2 1 Interferon-induced transmembrane protein VMA21 PF09446.10 OWF36528.1 - 0.025 14.7 1.9 0.04 14.0 1.9 1.3 1 0 0 1 1 1 0 VMA21-like domain DUF485 PF04341.12 OWF36528.1 - 0.16 12.0 4.8 0.9 9.5 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF485 CD225 PF04505.12 OWF36529.1 - 1.8e-21 76.0 0.5 3.5e-21 75.1 0.5 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF485 PF04341.12 OWF36529.1 - 0.0014 18.6 1.1 0.33 10.9 0.8 2.1 2 0 0 2 2 2 2 Protein of unknown function, DUF485 VMA21 PF09446.10 OWF36529.1 - 0.013 15.6 1.6 0.022 14.8 1.6 1.3 1 0 0 1 1 1 0 VMA21-like domain DUF1467 PF07330.12 OWF36529.1 - 0.065 13.2 0.6 0.18 11.8 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1467) DUF1771 PF08590.10 OWF36529.1 - 0.15 12.5 1.4 0.22 11.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DUF3270 PF11674.8 OWF36529.1 - 0.18 12.0 0.0 0.4 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) NAD_binding_10 PF13460.6 OWF36530.1 - 8.2e-40 136.7 0.0 9.3e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OWF36530.1 - 1e-06 28.5 0.0 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 OWF36530.1 - 1.8e-05 24.3 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OWF36530.1 - 0.0013 19.0 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OWF36530.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OWF36530.1 - 0.15 12.5 0.0 0.45 11.0 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OWF36530.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pep_M12B_propep PF01562.19 OWF36531.1 - 3.5e-14 53.2 0.2 7.1e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 OWF36531.1 - 1.4e-13 51.2 0.0 1.4e-13 51.2 0.0 2.3 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 OWF36531.1 - 5.5e-12 46.2 2.1 5.5e-12 46.2 2.1 4.6 3 2 0 3 3 3 1 Metallo-peptidase family M12 TSP_1 PF00090.19 OWF36531.1 - 1.9e-11 44.0 7.2 1.9e-11 44.0 7.2 5.8 6 0 0 6 6 6 1 Thrombospondin type 1 domain Reprolysin_3 PF13582.6 OWF36531.1 - 3.5e-10 40.5 0.6 1.7e-09 38.2 0.3 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Ldl_recept_a PF00057.18 OWF36531.1 - 5.7e-09 36.0 13.7 5.7e-09 36.0 13.7 3.1 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Reprolysin_4 PF13583.6 OWF36531.1 - 9.1e-09 35.2 1.0 2.6e-08 33.7 1.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF36531.1 - 7.7e-06 25.9 0.2 7.7e-06 25.9 0.2 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.14 OWF36531.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Peptidase_M10 PF00413.24 OWF36531.1 - 0.049 13.5 0.2 0.084 12.7 0.2 1.5 1 1 0 1 1 1 0 Matrixin Arfaptin PF06456.13 OWF36532.1 - 1.8e-18 67.0 9.9 2.1e-05 24.2 1.7 4.1 1 1 2 3 3 3 3 Arfaptin-like domain DUF948 PF06103.11 OWF36532.1 - 7.6e-15 54.9 3.7 0.00014 22.1 0.0 3.7 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) HTH_48 PF17906.1 OWF36532.1 - 5.9e-13 48.7 22.1 3.4 7.8 0.3 9.7 1 1 4 5 5 5 0 HTH domain in Mos1 transposase DnaJ-X PF14308.6 OWF36532.1 - 1.1e-12 47.8 13.2 0.016 14.6 0.5 4.6 1 1 4 5 5 5 5 X-domain of DnaJ-containing BAG6 PF12057.8 OWF36532.1 - 2.4e-12 46.6 1.2 0.13 12.0 0.2 6.9 1 1 2 3 3 3 3 BCL2-associated athanogene 6 Sec34 PF04136.15 OWF36532.1 - 6.4e-10 39.1 11.4 0.022 14.6 1.8 4.1 1 1 2 3 3 3 3 Sec34-like family MCPsignal PF00015.21 OWF36532.1 - 6.8e-10 39.0 12.8 0.0057 16.5 1.4 3.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain IFT57 PF10498.9 OWF36532.1 - 3.1e-09 36.3 37.0 0.03 13.3 3.4 4.4 1 1 3 4 4 4 4 Intra-flagellar transport protein 57 DUF1664 PF07889.12 OWF36532.1 - 2.3e-08 34.1 5.5 0.066 13.3 5.5 3.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) GAS PF13851.6 OWF36532.1 - 4.9e-08 32.6 9.9 0.028 13.8 1.0 3.7 1 1 3 4 4 4 4 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 OWF36532.1 - 8.1e-08 32.4 11.6 5.3 7.1 11.6 3.7 1 1 0 1 1 1 0 Laminin Domain II SNAP PF14938.6 OWF36532.1 - 8.9e-08 31.9 21.0 2.7e-05 23.8 6.7 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OWF36532.1 - 9.5e-08 32.2 3.1 16 5.8 0.0 6.3 1 1 8 9 9 9 0 Tetratricopeptide repeat Senescence PF06911.12 OWF36532.1 - 1.1e-07 32.4 21.6 8.2 6.7 0.9 7.8 1 1 8 9 9 9 0 Senescence-associated protein PI3K_P85_iSH2 PF16454.5 OWF36532.1 - 2.9e-07 30.2 25.6 1.5 8.4 0.5 5.8 1 1 2 3 3 3 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMP_2 PF06791.13 OWF36532.1 - 3.2e-07 30.2 0.0 0.058 13.1 0.0 3.1 1 1 2 3 3 3 3 Prophage tail length tape measure protein DUF4795 PF16043.5 OWF36532.1 - 4.3e-07 29.7 2.4 3.9 7.0 0.1 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4795) T2SSF PF00482.23 OWF36532.1 - 4.9e-07 29.8 0.9 0.77 9.7 0.1 4.8 1 1 2 3 3 3 3 Type II secretion system (T2SS), protein F DUF4872 PF16169.5 OWF36532.1 - 5.4e-07 29.5 0.0 0.93 9.2 0.0 4.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4872) RmuC PF02646.16 OWF36532.1 - 8.6e-07 28.4 13.1 0.083 12.0 0.9 3.7 1 1 2 3 3 3 3 RmuC family DUF812 PF05667.11 OWF36532.1 - 7.8e-06 25.1 16.3 0.00011 21.3 2.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF812) DUF148 PF02520.17 OWF36532.1 - 8.6e-06 25.8 18.8 0.094 12.8 2.4 3.6 1 1 3 4 4 4 4 Domain of unknown function DUF148 Lebercilin PF15619.6 OWF36532.1 - 8.9e-06 25.5 11.2 1.6 8.3 0.6 4.7 1 1 5 6 6 6 3 Ciliary protein causing Leber congenital amaurosis disease Med30 PF11315.8 OWF36532.1 - 1.1e-05 25.6 11.9 0.12 12.6 2.9 3.7 1 1 1 2 2 2 2 Mediator complex subunit 30 FH2 PF02181.23 OWF36532.1 - 5.5e-05 22.5 11.9 0.081 12.0 0.8 3.2 1 1 1 2 2 2 2 Formin Homology 2 Domain LXG PF04740.12 OWF36532.1 - 7e-05 22.6 10.7 0.05 13.3 5.8 2.8 1 1 1 2 2 2 2 LXG domain of WXG superfamily TMPIT PF07851.13 OWF36532.1 - 0.00024 20.5 16.0 0.037 13.3 5.9 2.3 1 1 1 2 2 2 2 TMPIT-like protein Laminin_I PF06008.14 OWF36532.1 - 0.00045 20.0 7.1 0.87 9.2 1.1 3.5 1 1 2 3 3 3 2 Laminin Domain I Jnk-SapK_ap_N PF09744.9 OWF36532.1 - 0.00048 20.4 17.3 2.7e+02 1.7 17.3 3.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Gp-FAR-1 PF05823.12 OWF36532.1 - 0.00071 19.9 8.4 0.62 10.4 1.5 3.3 1 1 2 3 3 3 2 Nematode fatty acid retinoid binding protein (Gp-FAR-1) EzrA PF06160.12 OWF36532.1 - 0.0012 17.2 30.6 0.096 10.8 15.5 2.9 1 1 2 3 3 3 3 Septation ring formation regulator, EzrA DUF745 PF05335.13 OWF36532.1 - 0.0035 17.1 4.3 7.3 6.3 4.3 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF745) NOG1_N PF17835.1 OWF36532.1 - 0.0061 16.5 17.0 1 9.3 6.6 3.7 1 1 2 3 3 3 2 NOG1 N-terminal helical domain BLOC1S3 PF15753.5 OWF36532.1 - 0.0098 16.0 12.5 7.7 6.6 0.5 4.1 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Mce4_CUP1 PF11887.8 OWF36532.1 - 0.012 15.1 6.0 1.1 8.6 1.7 2.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative SLATT_5 PF18160.1 OWF36532.1 - 0.012 15.0 32.6 0.52 9.6 7.0 3.9 1 1 1 2 2 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF1054 PF06335.12 OWF36532.1 - 0.013 15.4 6.0 1.1 9.1 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) Syntaxin PF00804.25 OWF36532.1 - 0.016 14.9 15.5 0.41 10.3 5.9 2.2 1 1 1 2 2 2 0 Syntaxin BLOC1_2 PF10046.9 OWF36532.1 - 0.02 15.2 23.5 1.7 9.0 2.9 4.0 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 OWF36532.1 - 0.024 15.0 9.3 2.4 8.6 2.6 3.3 1 1 2 3 3 3 0 Centromere protein H (CENP-H) PhoU PF01895.19 OWF36532.1 - 0.052 14.0 8.1 2.9e+02 2.0 8.1 3.4 1 1 0 1 1 1 0 PhoU domain Rab5-bind PF09311.11 OWF36532.1 - 0.13 11.6 10.3 2.5 7.4 3.6 2.5 1 1 1 2 2 2 0 Rabaptin-like protein Fib_alpha PF08702.10 OWF36532.1 - 0.14 12.3 30.4 3.4 7.8 5.7 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HemX PF04375.14 OWF36532.1 - 0.15 11.3 1.8 8.1 5.6 0.5 2.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase SOR_SNZ PF01680.17 OWF36532.1 - 0.22 11.3 2.7 27 4.5 0.9 3.1 1 1 1 2 2 2 0 SOR/SNZ family Occludin_ELL PF07303.13 OWF36532.1 - 0.27 12.0 31.5 1.8e+04 -14.5 31.5 3.8 1 1 0 1 1 0 0 Occludin homology domain Myosin_tail_1 PF01576.19 OWF36532.1 - 0.36 8.6 4.8 0.44 8.3 4.8 1.0 1 0 0 1 1 1 0 Myosin tail DUF3450 PF11932.8 OWF36532.1 - 0.39 10.0 15.3 11 5.2 8.7 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FPP PF05911.11 OWF36532.1 - 0.42 8.7 7.7 0.52 8.4 7.7 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DASH_Duo1 PF08651.10 OWF36532.1 - 0.47 10.3 14.1 32 4.4 0.1 5.4 1 1 4 5 5 5 0 DASH complex subunit Duo1 AATF-Che1 PF13339.6 OWF36532.1 - 0.79 10.4 12.7 6e+02 1.1 12.7 2.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor AsnA PF03590.15 OWF36532.1 - 1.4 8.6 23.1 9.4 5.9 0.7 4.8 1 1 3 4 4 4 0 Aspartate-ammonia ligase YabA PF06156.13 OWF36532.1 - 1.7 9.3 15.5 1.6e+04 -3.4 15.5 3.5 1 1 0 1 1 0 0 Initiation control protein YabA RuvC PF02075.17 OWF36532.1 - 4.3 7.2 4.2 5.9 6.8 0.4 2.9 1 1 2 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC Peptidase_S64 PF08192.11 OWF36532.1 - 4.7 5.6 23.7 6.6 5.1 23.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 zf-RING_UBOX PF13445.6 OWF36533.1 - 4.6e-12 45.8 3.6 4.6e-12 45.8 3.6 2.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF36533.1 - 3e-10 39.8 6.1 3e-10 39.8 6.1 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF36533.1 - 1.6e-09 37.4 2.3 1.6e-09 37.4 2.3 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF36533.1 - 3.4e-09 36.7 6.4 3.4e-09 36.7 6.4 3.0 2 2 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF36533.1 - 1.1e-08 35.2 5.7 1.1e-08 35.2 5.7 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF36533.1 - 9.5e-08 31.9 5.5 9.5e-08 31.9 5.5 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF36533.1 - 4.4e-07 29.6 6.1 4.4e-07 29.6 6.1 3.0 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OWF36533.1 - 0.0043 16.8 3.7 0.0094 15.7 3.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OWF36533.1 - 0.044 13.5 4.5 0.044 13.5 4.5 2.4 3 0 0 3 3 2 0 RING-like zinc finger zf-WRNIP1_ubi PF18279.1 OWF36533.1 - 0.11 13.2 5.5 0.74 10.6 0.7 3.1 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn-C2H2_12 PF18112.1 OWF36533.1 - 0.69 10.4 5.3 23 5.5 0.2 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_4 PF14447.6 OWF36533.1 - 5.9 6.8 23.4 0.72 9.8 13.0 3.9 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 zf-B_box PF00643.24 OWF36534.1 - 6e-05 23.1 31.2 0.00021 21.4 11.4 3.3 3 1 0 3 3 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF36535.1 - 1.4e-10 41.0 11.6 2.3e-10 40.3 11.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF36535.1 - 3.3e-09 36.8 10.0 7.5e-09 35.6 10.0 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF36535.1 - 5.8e-09 35.7 11.6 8.9e-09 35.1 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF36535.1 - 6.9e-08 32.7 10.8 1e-07 32.2 10.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF36535.1 - 2e-07 30.7 14.4 4.6e-06 26.4 14.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF36535.1 - 2.3e-07 30.7 9.9 3.4e-07 30.1 9.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF36535.1 - 1.6e-05 24.7 11.1 3.4e-05 23.6 11.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OWF36535.1 - 0.012 15.4 5.3 0.017 14.9 5.3 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OWF36535.1 - 0.02 14.8 15.0 0.72 9.8 15.9 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Anti-TRAP PF15777.5 OWF36535.1 - 0.057 13.4 4.3 0.12 12.3 1.3 2.4 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-MIZ PF02891.20 OWF36535.1 - 0.21 11.4 11.1 0.51 10.1 11.1 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.6 OWF36535.1 - 0.33 10.8 7.9 1.7 8.5 7.9 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD_4 PF16866.5 OWF36535.1 - 0.48 10.6 7.1 7.9 6.6 7.1 2.1 1 1 0 1 1 1 0 PHD-finger zf-RING_6 PF14835.6 OWF36535.1 - 0.58 10.1 9.6 2.3 8.2 9.5 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-B_box PF00643.24 OWF36536.1 - 0.00064 19.8 26.0 0.028 14.6 10.3 2.9 2 1 0 2 2 2 2 B-box zinc finger Baculo_PEP_C PF04513.12 OWF36536.1 - 0.0015 18.6 2.0 0.003 17.6 2.0 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 OWF36536.1 - 0.053 13.6 7.8 0.086 12.9 7.8 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Lipoprotein_3 PF00938.17 OWF36536.1 - 0.076 13.2 2.6 0.14 12.3 1.9 1.8 1 1 1 2 2 2 0 Lipoprotein Exonuc_VII_L PF02601.15 OWF36536.1 - 0.14 11.7 3.9 0.16 11.5 3.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 OWF36536.1 - 0.15 12.2 5.0 0.74 9.9 3.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_C50 PF03568.17 OWF36536.1 - 0.18 10.9 9.6 0.1 11.7 6.4 2.0 1 1 1 2 2 2 0 Peptidase family C50 KxDL PF10241.9 OWF36536.1 - 0.19 12.0 8.5 1.1 9.6 4.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein WXG100 PF06013.12 OWF36536.1 - 0.2 11.9 5.4 0.92 9.8 0.9 2.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Cortex-I_coil PF09304.10 OWF36536.1 - 0.6 10.3 11.3 1.7 8.9 3.9 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil APC1_C PF18122.1 OWF36536.1 - 0.97 9.4 6.7 2.1 8.3 6.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain PHD_2 PF13831.6 OWF36536.1 - 1.6 8.4 16.5 2.3 7.9 3.4 3.6 3 0 0 3 3 3 0 PHD-finger DUF948 PF06103.11 OWF36536.1 - 1.6 9.0 4.0 4.1 7.7 1.6 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 OWF36536.1 - 2.1 8.8 13.5 0.42 11.0 8.8 2.2 2 1 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.12 OWF36536.1 - 2.1 8.4 6.6 13 5.9 6.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YtxH PF12732.7 OWF36536.1 - 5.3 7.6 5.2 59 4.3 5.2 2.4 1 1 0 1 1 1 0 YtxH-like protein DUF4446 PF14584.6 OWF36536.1 - 6.6 6.7 8.4 3.7 7.5 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) zf-RING_UBOX PF13445.6 OWF36537.1 - 8.4e-12 44.9 2.9 9.6e-12 44.7 2.9 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF36537.1 - 3.9e-10 39.4 2.0 4.6e-10 39.2 2.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF36537.1 - 7.1e-10 38.6 2.4 8.9e-10 38.2 2.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF36537.1 - 3.7e-09 36.6 3.2 4.4e-09 36.4 3.2 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF36537.1 - 3.6e-07 30.4 1.9 4.4e-07 30.1 1.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF36537.1 - 2.1e-06 27.6 1.5 2.5e-06 27.3 1.5 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF36537.1 - 1.1e-05 25.2 1.4 1.1e-05 25.1 1.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF36537.1 - 0.0052 16.6 6.1 0.62 10.0 0.1 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OWF36537.1 - 0.02 14.7 0.1 0.025 14.4 0.1 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OWF36537.1 - 0.023 14.4 3.8 0.043 13.6 3.8 1.5 1 1 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 OWF36537.1 - 0.036 13.8 1.7 0.045 13.5 1.7 1.1 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger 2OG-FeII_Oxy PF03171.20 OWF36538.1 - 2.7e-15 56.7 0.0 4.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OWF36538.1 - 1.4e-14 54.9 0.1 2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PI3_PI4_kinase PF00454.27 OWF36539.1 - 1.3e-54 185.7 1.4 1.3e-54 185.7 1.4 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OWF36539.1 - 7.5e-42 142.8 1.1 1.8e-41 141.6 1.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) C2 PF00168.30 OWF36539.1 - 2.6e-17 63.0 0.2 6.4e-17 61.7 0.2 1.7 1 0 0 1 1 1 1 C2 domain PI3K_rbd PF00794.18 OWF36539.1 - 3e-15 56.3 0.7 8.6e-15 54.8 0.7 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 OWF36539.1 - 3.8e-14 52.8 0.6 3.2e-10 40.1 0.0 2.6 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 PX PF00787.24 OWF36539.1 - 4.5e-13 49.2 5.5 6.1e-13 48.7 2.8 2.7 3 0 0 3 3 3 1 PX domain DUF4135 PF13575.6 OWF36539.1 - 0.0054 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Lac_bphage_repr PF06543.12 OWF36539.1 - 0.079 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor PRORP PF16953.5 OWF36541.1 - 1.2e-29 103.5 0.0 1.8e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein-only RNase P PPR PF01535.20 OWF36541.1 - 0.019 15.2 3.0 4.4 7.8 0.1 4.0 5 0 0 5 5 5 0 PPR repeat UAA PF08449.11 OWF36542.1 - 2e-68 230.8 20.3 2.7e-68 230.4 20.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OWF36542.1 - 4.7e-05 23.6 23.5 0.0057 16.8 15.0 2.7 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OWF36542.1 - 0.0043 16.4 12.2 0.0073 15.7 11.0 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF5090 PF17009.5 OWF36542.1 - 6 6.8 9.5 7.7 6.4 7.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Proteasome PF00227.26 OWF36543.1 - 9.4e-53 178.5 0.6 1.4e-52 178.0 0.6 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OWF36543.1 - 1.8e-14 53.1 0.1 3.4e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 OWF36543.1 - 0.021 13.5 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) TPR_1 PF00515.28 OWF36544.1 - 2e-12 46.4 9.0 0.0025 17.5 0.7 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF36544.1 - 3.9e-09 35.9 23.7 0.00024 21.0 0.6 7.3 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF36544.1 - 3.1e-08 33.2 20.6 0.0049 17.0 0.6 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF36544.1 - 1.1e-06 29.0 7.7 0.00054 20.4 0.1 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF36544.1 - 1.3e-05 24.8 5.5 0.056 13.1 0.2 5.3 5 1 1 6 6 6 1 TPR repeat TPR_12 PF13424.6 OWF36544.1 - 1.5e-05 25.2 17.5 0.057 13.7 0.1 7.5 5 1 4 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF36544.1 - 3.5e-05 24.4 2.1 0.17 12.6 0.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF36544.1 - 8.5e-05 22.3 14.2 0.74 10.0 0.5 6.8 5 2 2 7 7 7 2 Tetratricopeptide repeat PPR PF01535.20 OWF36544.1 - 0.00019 21.4 2.6 0.54 10.6 0.0 4.2 3 0 0 3 3 3 2 PPR repeat TPR_10 PF13374.6 OWF36544.1 - 0.01 15.7 4.9 8.8 6.3 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat SPOB_a PF14689.6 OWF36544.1 - 0.012 15.3 0.6 0.44 10.3 0.0 3.3 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_17 PF13431.6 OWF36544.1 - 0.019 15.3 2.6 3.7 8.1 0.2 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF36544.1 - 0.025 15.4 6.7 68 4.7 0.0 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.17 OWF36544.1 - 0.27 11.7 3.0 8.5 6.8 0.0 3.7 4 0 0 4 4 4 0 Bacterial transcriptional activator domain KapB PF08810.10 OWF36545.1 - 0.00028 21.0 10.3 5.6 7.2 0.5 4.9 1 1 3 4 4 4 4 Kinase associated protein B Octopine_DH PF02317.17 OWF36547.1 - 7e-34 117.1 0.0 1.1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Staph_opine_DH PF10100.9 OWF36547.1 - 0.00045 19.0 0.0 0.021 13.4 0.0 2.1 2 0 0 2 2 2 2 Staphylopine dehydrogenase Pkinase_Tyr PF07714.17 OWF36548.1 - 5.7e-87 291.3 0.0 8.1e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF36548.1 - 1.3e-44 152.5 0.0 2.1e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF36548.1 - 5.1e-29 100.2 0.0 2.8e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 SH2 domain Haspin_kinase PF12330.8 OWF36548.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain NAGLU PF05089.12 OWF36549.1 - 5.1e-137 456.3 6.3 7.1e-137 455.8 6.3 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OWF36549.1 - 5.1e-76 255.7 0.6 7.4e-76 255.2 0.6 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OWF36549.1 - 3.4e-22 78.0 0.0 6.8e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF5617 PF18493.1 OWF36551.1 - 0.08 13.1 0.3 3.6 7.7 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5617) DUF2452 PF10504.9 OWF36551.1 - 0.46 9.9 2.5 1.6 8.2 0.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2452) FAM47 PF14642.6 OWF36552.1 - 1.2e-19 70.9 0.1 0.0061 16.2 0.0 5.0 1 1 4 5 5 5 5 FAM47 family Cuticle_3 PF11018.8 OWF36552.1 - 3e-18 66.7 51.2 0.00054 20.2 6.2 4.9 1 1 4 5 5 5 5 Pupal cuticle protein C1 DmpG_comm PF07836.11 OWF36552.1 - 3.1 7.4 15.3 1.3e+02 2.2 0.0 6.9 6 6 0 6 6 6 0 DmpG-like communication domain AA_permease_2 PF13520.6 OWF36555.1 - 8.7e-54 183.0 38.6 1.1e-53 182.7 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF36555.1 - 1.3e-31 109.8 36.3 1.6e-31 109.5 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 OWF36556.1 - 5.9e-78 262.3 0.0 7.1e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF36556.1 - 2.9e-21 76.2 0.5 5.6e-21 75.3 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC2_membrane PF01061.24 OWF36557.1 - 1.8e-41 141.9 23.8 3.1e-41 141.1 23.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OWF36557.1 - 6.7e-23 81.7 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF36557.1 - 6.8e-07 29.4 1.2 0.007 16.2 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OWF36557.1 - 1.5e-05 24.3 27.3 0.0001 21.6 27.3 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 OWF36557.1 - 1.7e-05 24.4 0.1 0.0012 18.3 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OWF36557.1 - 8.5e-05 23.1 0.3 0.00017 22.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF36557.1 - 0.0028 17.3 0.3 0.007 16.1 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OWF36557.1 - 0.003 17.5 0.1 0.0082 16.1 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 OWF36557.1 - 0.14 12.2 0.3 0.37 10.9 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain PMP22_Claudin PF00822.20 OWF36558.1 - 6.8e-07 29.3 4.6 6.5e-06 26.1 0.7 1.7 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF36558.1 - 0.00065 19.5 0.8 0.00075 19.3 0.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction BatA PF07584.11 OWF36558.1 - 0.071 13.5 0.0 6.1 7.3 0.0 2.2 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal Tegument_dsDNA PF12818.7 OWF36558.1 - 0.095 11.8 0.0 0.15 11.2 0.0 1.3 1 1 0 1 1 1 0 dsDNA viral tegument protein Peptidase_C48 PF02902.19 OWF36560.1 - 1.3e-08 34.9 2.8 2e-08 34.4 2.8 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PLAC8 PF04749.17 OWF36561.1 - 1.7e-20 73.8 6.5 2e-20 73.6 6.5 1.0 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 OWF36562.1 - 7.9e-11 42.8 0.5 9.2e-11 42.6 0.5 1.0 1 0 0 1 1 1 1 PLAC8 family Zip PF02535.22 OWF36564.1 - 9.8e-76 255.1 20.2 1e-75 255.1 10.7 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter TMEM132D_C PF15706.5 OWF36564.1 - 0.0085 15.8 0.0 0.58 10.0 0.0 2.7 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF3325 PF11804.8 OWF36564.1 - 0.019 15.1 0.1 0.44 10.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF2514 PF10721.9 OWF36564.1 - 0.034 14.2 0.2 3.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) ABC_cobalt PF09819.9 OWF36564.1 - 0.062 13.4 3.4 0.31 11.2 0.0 3.0 2 1 1 3 3 3 0 ABC-type cobalt transport system, permease component DUF4834 PF16118.5 OWF36564.1 - 0.074 14.0 0.0 0.58 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Myco_haema PF05692.12 OWF36564.1 - 0.094 11.7 0.3 0.14 11.1 0.3 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin Trp_oprn_chp PF09534.10 OWF36564.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_hydro_31 PF01055.26 OWF36565.1 - 4.1e-57 194.3 0.4 6.5e-57 193.7 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 OWF36565.1 - 3.3e-06 26.3 0.4 1.5e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Melibiase Glyco_hydro_31 PF01055.26 OWF36566.1 - 1.4e-47 162.9 1.1 4.2e-47 161.3 1.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 zf-RING_5 PF14634.6 OWF36567.1 - 1.5e-10 40.9 10.0 2.8e-10 40.0 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain RepL PF05732.11 OWF36567.1 - 0.00021 20.8 0.1 0.00032 20.2 0.1 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) Prok-RING_4 PF14447.6 OWF36567.1 - 0.00023 20.9 7.5 0.00057 19.7 7.5 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OWF36567.1 - 0.00025 20.9 7.2 0.00058 19.7 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF36567.1 - 0.0035 17.6 8.0 0.0095 16.2 8.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF36567.1 - 0.014 15.4 8.3 0.035 14.1 8.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DHR10 PF18595.1 OWF36567.1 - 0.027 14.5 0.9 0.027 14.5 0.9 1.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain FNIP_M PF14637.6 OWF36567.1 - 0.041 13.9 0.9 0.06 13.3 0.9 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain TSC22 PF01166.18 OWF36567.1 - 0.061 13.6 0.2 0.061 13.6 0.2 1.8 2 0 0 2 2 1 0 TSC-22/dip/bun family HeLo PF14479.6 OWF36567.1 - 0.09 12.6 2.8 0.09 12.6 2.0 1.3 1 1 0 1 1 1 0 Prion-inhibition and propagation zf-C3HC4_2 PF13923.6 OWF36567.1 - 0.094 12.6 11.3 0.56 10.1 11.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OWF36567.1 - 0.84 9.6 6.7 1.7 8.6 6.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OWF36567.1 - 3.9 7.6 8.0 8.5 6.5 8.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Activin_recp PF01064.23 OWF36568.1 - 2.5 9.3 15.6 4.1 8.6 15.6 1.4 1 0 0 1 1 1 0 Activin types I and II receptor domain Cyclin_N PF00134.23 OWF36570.1 - 1.7e-19 69.8 1.2 1.7e-19 69.8 1.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain PIH1 PF08190.12 OWF36570.1 - 0.09 12.2 0.2 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 PIH1 N-terminal domain Cyclin_N PF00134.23 OWF36571.1 - 5.6e-23 81.1 3.1 7.5e-23 80.7 0.8 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OWF36571.1 - 0.1 13.0 0.1 3.6 8.0 0.0 2.6 2 1 0 2 2 2 0 Cyclin C-terminal domain Neur_chan_LBD PF02931.23 OWF36572.1 - 8.1e-19 67.9 1.9 1.1e-18 67.5 1.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF36572.1 - 5e-12 46.4 3.9 5e-12 46.4 3.9 2.0 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.16 OWF36573.1 - 1.8e-53 181.8 28.3 1.5e-52 178.7 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 OWF36573.1 - 0.0054 15.0 0.5 0.013 13.7 0.0 1.8 2 0 0 2 2 2 1 BT1 family Pheromone PF08015.11 OWF36574.1 - 2 9.5 20.0 1.7 9.7 4.0 2.7 2 1 0 2 2 2 0 Fungal mating-type pheromone Carn_acyltransf PF00755.20 OWF36575.1 - 3.8e-189 630.1 0.0 4.5e-189 629.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ependymin PF00811.18 OWF36576.1 - 1.7e-09 38.0 0.1 2.6e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF36577.1 - 9.3e-14 51.8 0.7 2e-13 50.7 0.2 1.6 2 0 0 2 2 2 1 Ependymin RIFIN PF02009.16 OWF36579.1 - 0.00033 20.6 0.4 0.00033 20.6 0.4 1.7 2 0 0 2 2 2 1 Rifin DUF1180 PF06679.12 OWF36579.1 - 0.0092 16.4 4.6 0.033 14.6 4.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 OWF36579.1 - 0.043 14.7 0.0 0.21 12.5 0.0 2.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OWF36579.1 - 0.11 12.8 0.6 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) ECSCR PF15820.5 OWF36579.1 - 0.22 11.4 3.5 1.4 8.7 0.8 2.6 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF5383 PF17355.2 OWF36579.1 - 0.97 9.8 4.5 0.72 10.2 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) G_glu_transpept PF01019.21 OWF36580.1 - 6.8e-167 556.3 0.0 8e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase bMG5 PF17972.1 OWF36580.1 - 0.18 12.2 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain EF-hand_7 PF13499.6 OWF36581.1 - 2e-23 82.6 19.6 6.6e-09 36.1 0.1 7.4 7 1 0 7 7 7 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF36581.1 - 1.5e-16 58.8 17.7 0.00062 19.5 0.0 10.8 11 0 0 11 11 11 3 EF-hand domain EF-hand_11 PF08976.11 OWF36581.1 - 2e-16 60.8 12.3 0.0011 19.8 0.3 6.8 7 0 0 7 7 7 4 EF-hand domain EF-hand_8 PF13833.6 OWF36581.1 - 4.2e-15 55.3 7.0 8.2e-06 25.6 0.1 6.7 6 1 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF36581.1 - 2.7e-10 39.0 18.6 0.0022 17.4 0.0 10.3 11 0 0 11 11 11 2 EF hand KilA-N PF04383.13 OWF36581.1 - 0.016 15.0 0.3 0.058 13.2 0.3 1.9 1 0 0 1 1 1 0 KilA-N domain EF-hand_5 PF13202.6 OWF36581.1 - 0.025 14.1 1.1 11 5.7 0.0 4.4 4 0 0 4 4 4 0 EF hand DUF1806 PF08830.10 OWF36582.1 - 0.001 18.9 2.1 0.11 12.4 0.1 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF1806) TOBE_2 PF08402.10 OWF36582.1 - 1.1 9.5 3.8 31 4.8 0.2 3.6 2 2 1 3 3 3 0 TOBE domain Dimer_Tnp_hAT PF05699.14 OWF36583.1 - 7.1e-05 22.5 7.6 23 4.8 0.1 7.5 1 1 9 10 10 10 3 hAT family C-terminal dimerisation region Mg_trans_NIPA PF05653.14 OWF36583.1 - 0.0012 18.0 2.2 6.5 5.8 0.1 3.6 1 1 2 4 4 4 4 Magnesium transporter NIPA DUF3368 PF11848.8 OWF36583.1 - 0.14 12.0 0.3 92 2.9 0.0 4.8 8 0 0 8 8 8 0 Domain of unknown function (DUF3368) Lipase_GDSL_2 PF13472.6 OWF36584.1 - 1.9e-09 38.2 0.0 4.6e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF36584.1 - 0.0013 18.8 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amino_oxidase PF01593.24 OWF36585.1 - 3.4e-57 194.7 0.0 4e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF36585.1 - 6.3e-13 48.7 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF36585.1 - 1e-08 34.8 0.8 2.3e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OWF36585.1 - 2.5e-08 33.9 0.2 4.8e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OWF36585.1 - 7.3e-06 25.3 0.1 1.2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OWF36585.1 - 9e-06 25.0 0.8 0.00037 19.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OWF36585.1 - 9.3e-05 21.8 0.1 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF36585.1 - 0.00013 20.8 2.3 0.0086 14.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OWF36585.1 - 0.0017 17.8 0.2 0.0039 16.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OWF36585.1 - 0.0069 16.4 1.5 0.021 14.8 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OWF36585.1 - 0.012 16.1 0.4 0.08 13.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF36585.1 - 0.039 13.0 0.9 0.26 10.3 0.2 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A MCRA PF06100.11 OWF36585.1 - 0.044 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 OWF36585.1 - 0.068 12.4 0.4 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF36585.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OWF36585.1 - 0.17 11.1 0.4 0.34 10.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain DUF4573 PF15140.6 OWF36586.1 - 3.9e-36 124.5 64.7 9e-11 41.9 11.2 4.4 1 1 3 4 4 4 4 Domain of unknown function (DUF4573) Kin17_mid PF10357.9 OWF36588.1 - 9.6e-51 171.0 2.6 3.3e-50 169.2 2.6 2.0 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 OWF36588.1 - 4.5e-20 71.5 9.9 4.5e-20 71.5 9.9 1.9 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-C2H2_2 PF12756.7 OWF36588.1 - 0.003 17.8 0.6 0.003 17.8 0.6 2.7 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) KOW PF00467.29 OWF36588.1 - 0.0035 17.3 3.1 0.017 15.0 0.0 3.3 2 1 1 3 3 3 1 KOW motif zf-met PF12874.7 OWF36588.1 - 0.0041 17.5 6.1 0.0094 16.3 6.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF36588.1 - 0.006 16.8 5.6 0.018 15.3 5.6 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding NABP PF07990.12 OWF36588.1 - 0.18 11.3 2.5 0.27 10.7 2.5 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Peptidase_M1 PF01433.20 OWF36589.1 - 1.1e-42 146.0 0.0 6.6e-42 143.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OWF36589.1 - 2.7e-34 117.7 0.1 4.4e-34 117.0 0.1 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OWF36589.1 - 1.7e-26 93.6 0.0 2.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 OWF36589.1 - 0.025 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 VP_N-CPKC PF11475.8 OWF36589.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Virion protein N terminal domain Ion_trans PF00520.31 OWF36590.1 - 3.2e-19 69.1 16.4 4.9e-19 68.5 16.4 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OWF36590.1 - 0.01 14.5 15.4 0.28 9.8 15.4 2.3 1 1 0 1 1 1 0 Polycystin cation channel Epimerase PF01370.21 OWF36591.1 - 1.5e-12 47.5 0.0 2.9e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OWF36591.1 - 0.011 14.9 0.0 0.09 11.9 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 OWF36591.1 - 0.1 12.0 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Lectin_C PF00059.21 OWF36592.1 - 2.1e-14 54.1 1.2 3e-14 53.6 1.2 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF36592.1 - 1.4e-06 28.1 0.7 7.5e-06 25.7 0.2 2.0 2 1 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF1057 PF06342.12 OWF36594.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) UCH PF00443.29 OWF36594.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CD36 PF01130.21 OWF36595.1 - 4.6e-142 473.8 4.9 5.5e-142 473.6 4.9 1.0 1 0 0 1 1 1 1 CD36 family PIRT PF15099.6 OWF36595.1 - 0.053 13.1 1.1 0.55 9.8 0.3 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family PorA PF11271.8 OWF36595.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Porin PorA FAM124 PF15067.6 OWF36597.1 - 3e-56 190.7 0.5 3.9e-56 190.3 0.5 1.1 1 0 0 1 1 1 1 FAM124 family Chromadorea_ALT PF05535.12 OWF36599.1 - 0.001 19.2 17.6 3.2 8.0 0.1 6.6 1 1 3 4 4 4 2 Chromadorea ALT protein CYTL1 PF15153.6 OWF36599.1 - 0.017 15.1 15.8 95 3.0 0.1 9.0 1 1 8 9 9 9 0 Cytokine-like protein 1 DUF2534 PF10749.9 OWF36599.1 - 0.26 11.5 17.8 9 6.5 0.2 5.9 1 1 5 6 6 6 0 Protein of unknown function (DUF2534) DUF2207 PF09972.9 OWF36601.1 - 9.9 4.8 5.6 22 3.6 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Oxidored_q6 PF01058.22 OWF36602.1 - 3.1e-22 78.8 0.1 4.9e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PINIT PF14324.6 OWF36603.1 - 2e-36 125.5 0.1 3.6e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OWF36603.1 - 8.3e-20 70.3 1.0 1.7e-19 69.3 1.0 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OWF36603.1 - 8.2e-06 25.5 0.4 2.4e-05 24.0 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 OWF36603.1 - 0.025 14.3 0.8 0.043 13.6 0.1 1.7 2 0 0 2 2 2 0 SAP domain Imm71 PF15602.6 OWF36603.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 71 Spp-24 PF07448.11 OWF36603.1 - 0.11 12.7 0.3 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain PepSY_like PF11396.8 OWF36603.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like DUF2733 PF10813.8 OWF36604.1 - 0.0056 16.4 6.3 37 4.2 0.0 4.9 2 1 3 5 5 5 1 Protein of unknown function (DUF2733) BACON PF13004.7 OWF36604.1 - 0.069 13.1 1.6 3.8 7.6 0.5 3.1 2 1 0 2 2 2 0 Putative binding domain, N-terminal DUF5026 PF16429.5 OWF36604.1 - 0.097 12.8 0.1 5.6 7.1 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5026) YjhX_toxin PF09857.9 OWF36604.1 - 0.099 12.6 1.7 2.4 8.2 0.4 2.3 1 1 1 2 2 2 0 Putative toxin of bacterial toxin-antitoxin pair YjhX_toxin PF09857.9 OWF36605.1 - 0.0023 17.9 1.3 3.5 7.6 0.1 3.1 1 1 3 4 4 4 4 Putative toxin of bacterial toxin-antitoxin pair DUF5487 PF17589.2 OWF36605.1 - 0.015 15.5 0.6 7.9 6.8 0.2 3.4 1 1 2 3 3 3 0 Family of unknown function (DUF5487) SAND PF01342.21 OWF36605.1 - 0.019 14.7 0.4 35 4.2 0.0 3.8 1 1 2 5 5 5 0 SAND domain BACON PF13004.7 OWF36605.1 - 0.1 12.6 0.9 29 4.8 0.3 3.6 1 1 1 3 3 3 0 Putative binding domain, N-terminal Proteasom_Rpn13 PF04683.13 OWF36605.1 - 0.18 12.4 0.0 21 5.7 0.0 2.1 1 1 1 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor SDH_alpha PF03313.15 OWF36605.1 - 0.57 9.8 4.9 3.9 7.1 0.4 2.1 1 1 1 2 2 2 0 Serine dehydratase alpha chain Ig_3 PF13927.6 OWF36606.1 - 6.6e-13 49.1 0.0 1.6e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF36606.1 - 2.4e-10 40.4 0.0 4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF36606.1 - 4.1e-09 36.7 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 OWF36606.1 - 2.2e-06 27.7 0.0 8.9e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF36606.1 - 0.049 13.7 0.2 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 C17orf99 Ig domain KAR9 PF08580.10 OWF36606.1 - 0.064 11.8 5.7 0.078 11.5 5.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF908 PF06012.12 OWF36606.1 - 1.2 8.5 4.3 1.5 8.1 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) EF-hand_1 PF00036.32 OWF36607.1 - 1.2e-28 96.5 16.0 2.5e-08 32.9 1.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF36607.1 - 5.9e-26 90.7 12.3 2.4e-14 53.5 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF36607.1 - 5e-23 79.0 12.7 2.4e-07 30.1 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF36607.1 - 4.8e-19 68.0 19.0 5.6e-12 45.3 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF36607.1 - 3.1e-11 42.2 13.4 0.00073 18.9 1.6 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF36607.1 - 1.6e-08 34.7 1.1 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF36607.1 - 0.00012 21.9 6.0 0.011 15.7 0.3 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF36607.1 - 0.002 18.1 1.9 1.1 9.2 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 OWF36607.1 - 0.0051 17.1 2.9 0.15 12.4 0.5 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region SUB1_ProdP9 PF18213.1 OWF36607.1 - 0.011 15.6 0.2 0.018 14.9 0.2 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 OWF36607.1 - 0.012 15.9 2.1 0.87 10.0 0.2 2.7 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 OWF36607.1 - 0.019 14.8 1.3 0.26 11.1 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain MgtE_N PF03448.17 OWF36607.1 - 0.043 14.4 0.4 0.043 14.4 0.4 2.3 2 1 1 3 3 3 0 MgtE intracellular N domain DUF455 PF04305.14 OWF36608.1 - 7e-96 320.5 0.0 8.5e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 OWF36608.1 - 1.2e-09 37.9 0.1 4.8e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OWF36608.1 - 5.6e-09 35.9 0.0 1.6e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain eIF-1a PF01176.19 OWF36609.1 - 1.7e-20 72.6 0.3 2.4e-20 72.1 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 LLC1 PF14945.6 OWF36610.1 - 2.1e-22 79.9 0.0 2.7e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.6 OWF36610.1 - 0.005 17.6 0.7 0.05 14.3 0.1 2.1 2 0 0 2 2 2 1 FAM183A and FAM183B related Glyco_transf_92 PF01697.27 OWF36611.1 - 7.2e-43 147.1 1.9 7.2e-43 147.1 1.9 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 OWF36611.1 - 0.0062 17.0 0.0 0.025 15.1 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 DiS_P_DiS PF06750.13 OWF36612.1 - 6.7 6.9 10.2 64 3.8 10.2 2.1 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Bromodomain PF00439.25 OWF36613.1 - 3.8e-09 36.5 0.2 1e-08 35.1 0.2 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 OWF36613.1 - 5.5e-05 23.5 0.0 5.5e-05 23.5 0.0 3.7 2 2 0 2 2 2 1 PWWP domain zf-MYND PF01753.18 OWF36613.1 - 0.0073 16.4 22.6 0.0073 16.4 22.6 4.3 4 1 0 4 4 4 2 MYND finger Amino_oxidase PF01593.24 OWF36613.1 - 0.15 11.3 1.1 1.3 8.2 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase TM_helix PF05552.12 OWF36614.1 - 0.00047 20.1 0.1 23 5.1 0.0 5.9 4 2 4 8 8 8 1 Conserved TM helix DUF4253 PF14062.6 OWF36614.1 - 0.14 12.3 13.1 29 4.9 1.3 6.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4253) DUF3652 PF12372.8 OWF36614.1 - 0.17 11.8 2.4 87 3.1 0.1 4.2 4 1 1 5 5 5 0 Huntingtin protein region FGE-sulfatase PF03781.16 OWF36615.1 - 1.2e-67 228.3 3.9 1.5e-67 227.9 3.9 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 FGE-sulfatase PF03781.16 OWF36616.1 - 4e-39 134.8 2.6 2e-37 129.2 2.0 2.1 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 DUF4921 PF16268.5 OWF36616.1 - 0.12 11.2 0.2 0.28 9.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) IL17 PF06083.11 OWF36617.1 - 1.5e-13 51.0 0.5 1.9e-13 50.7 0.5 1.2 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 OWF36618.1 - 1.9e-12 47.4 0.4 3e-12 46.9 0.4 1.3 1 0 0 1 1 1 1 Interleukin-17 zf-RING_UBOX PF13445.6 OWF36619.1 - 5.8e-09 35.8 11.2 5.8e-09 35.8 11.2 2.9 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF36619.1 - 5.4e-07 29.4 10.0 5.4e-07 29.4 10.0 4.1 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF36619.1 - 6e-07 29.7 9.6 6e-07 29.7 9.6 4.1 3 1 1 4 4 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF36619.1 - 7.8e-07 28.8 5.5 7.8e-07 28.8 5.5 4.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF36619.1 - 4.8e-06 26.6 11.4 4.8e-06 26.6 11.4 3.8 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF36619.1 - 1.1e-05 25.2 8.7 1.1e-05 25.2 8.7 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF36619.1 - 2.6e-05 24.1 8.4 2.6e-05 24.1 8.4 4.2 4 1 1 5 5 3 1 zinc-RING finger domain zf-B_box PF00643.24 OWF36619.1 - 0.0011 19.1 7.8 0.0011 19.1 7.8 4.5 3 2 0 3 3 3 1 B-box zinc finger HrcA_DNA-bdg PF03444.15 OWF36619.1 - 0.12 12.1 0.3 7.4 6.3 0.1 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding KxDL PF10241.9 OWF36619.1 - 0.12 12.7 6.1 0.55 10.5 3.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Mit_KHE1 PF10173.9 OWF36619.1 - 0.12 12.4 0.5 0.19 11.8 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Baculo_PEP_C PF04513.12 OWF36619.1 - 0.15 12.1 2.5 0.46 10.5 2.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 OWF36619.1 - 0.67 10.4 6.9 1.4 9.4 6.9 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Snapin_Pallidin PF14712.6 OWF36619.1 - 1.9 9.0 7.0 3.1 8.3 4.9 2.2 1 1 1 2 2 2 0 Snapin/Pallidin zf-RING_UBOX PF13445.6 OWF36620.1 - 9.8e-10 38.3 9.3 4.5e-09 36.2 9.3 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF36620.1 - 3.8e-07 29.9 10.0 3.8e-07 29.9 10.0 3.5 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF36620.1 - 5.1e-07 29.9 9.5 5.1e-07 29.9 9.5 3.3 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF36620.1 - 5.6e-06 26.4 11.4 5.6e-06 26.4 11.4 2.8 4 0 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF36620.1 - 9.1e-06 25.4 7.5 9.1e-06 25.4 7.5 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF36620.1 - 2.4e-05 24.2 8.4 2.4e-05 24.2 8.4 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF36620.1 - 0.00012 21.8 12.7 0.00012 21.8 12.7 3.7 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF36620.1 - 0.00097 19.2 5.2 0.00097 19.2 5.2 4.3 3 1 0 3 3 3 2 B-box zinc finger DUF2387 PF09526.10 OWF36620.1 - 0.0047 17.1 0.9 0.0047 17.1 0.9 2.4 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) NHL PF01436.21 OWF36620.1 - 0.099 12.7 0.1 8.1 6.7 0.0 3.2 2 0 0 2 2 2 0 NHL repeat DUF3549 PF12069.8 OWF36620.1 - 0.36 9.8 3.6 0.59 9.1 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) CHASE3 PF05227.13 OWF36620.1 - 0.58 10.1 2.9 2.5 8.0 2.1 2.1 1 1 1 2 2 2 0 CHASE3 domain KxDL PF10241.9 OWF36620.1 - 1.2 9.4 7.0 7 7.0 3.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 OWF36620.1 - 1.8 8.6 6.7 3.7 7.6 5.4 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myb_DNA-bind_4 PF13837.6 OWF36621.1 - 2.6e-10 40.6 2.2 2.6e-10 40.6 2.2 1.7 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OWF36621.1 - 0.18 12.8 0.4 0.18 12.8 0.4 1.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 OWF36621.1 - 0.67 10.7 3.9 0.35 11.6 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF573 MFS_1 PF07690.16 OWF36623.1 - 1.9e-12 46.8 17.0 5.2e-12 45.4 17.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1003 PF06210.11 OWF36623.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) FKBP_C PF00254.28 OWF36624.1 - 3.9e-13 49.5 0.0 6.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 OWF36625.1 - 2.6e-11 43.8 1.7 2e-06 28.2 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF36625.1 - 2.2e-09 36.2 0.1 9.2e-06 24.9 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF36625.1 - 9.9e-09 34.4 0.1 0.00081 19.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain FKBP_C PF00254.28 OWF36625.1 - 4.7e-07 30.0 0.1 9e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_5 PF13202.6 OWF36625.1 - 4.1e-06 26.0 0.5 2.5e-05 23.5 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF36625.1 - 0.00014 21.6 0.3 0.0017 18.2 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF36625.1 - 0.19 12.1 1.8 0.44 10.9 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FKBP_C PF00254.28 OWF36626.1 - 2.7e-27 94.9 0.0 7.3e-27 93.5 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 OWF36626.1 - 9.3e-10 37.4 1.2 0.00083 18.7 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF36626.1 - 2.1e-09 36.5 0.8 0.00085 19.1 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF36626.1 - 4e-09 35.6 3.2 0.0016 17.8 1.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF36626.1 - 3.6e-05 24.1 3.4 0.00036 20.9 1.6 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF36626.1 - 0.024 14.5 1.5 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF36626.1 - 0.12 12.7 0.1 4.5 7.6 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_M1 PF01433.20 OWF36627.1 - 9.7e-91 303.2 0.6 1.7e-90 302.4 0.6 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OWF36627.1 - 2e-89 300.2 0.0 5.9e-88 295.4 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OWF36627.1 - 7.8e-39 133.8 0.0 2.2e-38 132.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain YajC PF02699.15 OWF36627.1 - 0.1 12.5 0.1 9.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit DUF5011 PF16403.5 OWF36627.1 - 0.13 12.4 0.1 9.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Peptidase_M1_N PF17900.1 OWF36629.1 - 3e-07 30.8 0.0 3.5e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain p450 PF00067.22 OWF36630.1 - 3e-121 405.4 0.0 3.6e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ORF6N PF10543.9 OWF36631.1 - 4.4e-06 26.8 7.3 46 4.3 0.0 7.6 1 1 7 8 8 8 0 ORF6N domain HTH_9 PF08221.11 OWF36631.1 - 2.1e-05 24.5 3.3 84 3.4 0.0 7.3 1 1 11 12 12 12 0 RNA polymerase III subunit RPC82 helix-turn-helix domain V-SNARE_C PF12352.8 OWF36631.1 - 0.0002 21.6 1.7 16 5.9 0.0 5.9 1 1 6 8 8 8 1 Snare region anchored in the vesicle membrane C-terminus Joubert PF15392.6 OWF36631.1 - 0.00047 20.0 13.8 1.1 9.0 0.4 5.9 1 1 6 7 7 7 2 Joubert syndrome-associated FRG PF08867.11 OWF36631.1 - 0.00074 20.4 15.7 17 6.4 1.8 9.1 1 1 2 3 3 3 1 FRG domain Suv3_N PF18114.1 OWF36631.1 - 0.0044 17.1 0.0 19 5.4 0.0 4.5 1 1 4 6 6 6 1 Suv3 helical N-terminal domain E3_UFM1_ligase PF09743.9 OWF36631.1 - 0.012 15.2 7.6 6.2 6.4 0.3 4.3 1 1 2 3 3 3 0 E3 UFM1-protein ligase 1 Mucin-like PF16058.5 OWF36631.1 - 0.027 14.5 0.0 0.4 10.8 0.0 2.2 1 1 1 2 2 2 0 Mucin-like Herpes_teg_N PF04843.12 OWF36631.1 - 0.27 10.9 3.8 5.8 6.6 1.1 3.2 1 1 2 3 3 3 0 Herpesvirus tegument protein, N-terminal conserved region Lectin_C PF00059.21 OWF36632.1 - 2.6e-18 66.7 3.7 4.2e-18 66.1 3.7 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF36632.1 - 0.011 15.4 0.7 0.029 14.0 0.7 1.7 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF36633.1 - 1.6e-16 61.0 0.5 2.1e-16 60.6 0.5 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 OWF36634.1 - 0.0006 20.5 0.0 0.0008 20.1 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain DUF3283 PF11686.8 OWF36634.1 - 0.11 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) UL45 PF05473.12 OWF36634.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF36635.1 - 1.6e-17 64.2 2.0 2.1e-17 63.8 2.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Sec3-PIP2_bind PF15277.6 OWF36635.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.6 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Ribul_P_3_epim PF00834.19 OWF36636.1 - 8.5e-69 230.9 0.3 1e-68 230.7 0.3 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OWF36636.1 - 0.0034 17.2 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain JmjN PF02375.17 OWF36636.1 - 0.028 14.4 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 jmjN domain OMPdecase PF00215.24 OWF36636.1 - 0.031 13.9 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 OWF36636.1 - 0.045 13.1 0.3 0.063 12.6 0.3 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 OWF36636.1 - 0.06 12.8 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein TPR_12 PF13424.6 OWF36637.1 - 2.9e-11 43.5 6.7 2.3e-06 27.8 0.1 5.1 3 2 3 6 6 5 4 Tetratricopeptide repeat NACHT PF05729.12 OWF36637.1 - 2e-08 34.3 0.0 4.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 OWF36637.1 - 4.7e-07 29.5 0.3 0.0075 16.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 OWF36637.1 - 7e-05 23.3 0.0 0.00039 20.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.6 OWF36637.1 - 0.00055 19.8 2.5 0.048 13.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF36637.1 - 0.00069 20.2 0.3 11 7.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF36637.1 - 0.0026 17.5 0.4 0.0026 17.5 0.4 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF36637.1 - 0.0042 17.1 11.8 0.071 13.3 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF36637.1 - 0.034 14.3 0.2 0.034 14.3 0.2 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF36637.1 - 0.12 12.9 1.5 1.8 9.1 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF36637.1 - 0.16 11.3 1.1 5 6.4 0.2 2.2 2 0 0 2 2 2 0 MalT-like TPR region ANAPC3 PF12895.7 OWF36637.1 - 1.1 9.5 7.4 3.4 8.0 0.1 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DAGK_cat PF00781.24 OWF36638.1 - 3e-22 78.6 0.1 4.5e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 OWF36638.1 - 9.6e-09 34.5 0.2 3.2e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 NAD_kinase PF01513.21 OWF36638.1 - 0.0091 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase 2-Hacid_dh_C PF02826.19 OWF36639.1 - 4.6e-51 172.7 0.0 7.2e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF36639.1 - 9.3e-30 103.0 0.0 1.1e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OWF36639.1 - 0.0038 17.4 0.0 0.0082 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 OWF36639.1 - 0.044 14.2 0.2 0.29 11.6 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 OWF36639.1 - 0.051 12.9 1.0 5.2 6.3 0.5 2.2 1 1 1 2 2 2 0 ThiF family FR47 PF08445.10 OWF36640.1 - 6.2e-16 58.1 0.0 1.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 OWF36640.1 - 3.5e-06 27.2 0.0 9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Gly_acyl_tr_N PF06021.11 OWF36640.1 - 0.0019 18.3 0.0 0.0027 17.9 0.0 1.2 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Gly_acyl_tr_C PF08444.10 OWF36640.1 - 0.0026 17.9 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_7 PF13508.7 OWF36640.1 - 0.0054 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF36640.1 - 0.0055 16.7 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OxoGdeHyase_C PF16870.5 OWF36640.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal Acetyltransf_3 PF13302.7 OWF36640.1 - 0.13 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cullin PF00888.22 OWF36641.1 - 2.3e-223 743.3 16.6 2.7e-223 743.1 16.6 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OWF36641.1 - 1.3e-27 95.7 2.8 4.1e-27 94.0 0.7 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3892 PF13031.6 OWF36642.1 - 0.008 16.8 0.6 2.4 8.8 0.2 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3892) GvpG PF05120.12 OWF36642.1 - 0.033 14.2 2.4 16 5.6 0.0 3.7 1 1 2 3 3 3 0 Gas vesicle protein G DCAF17 PF15802.5 OWF36642.1 - 0.069 11.8 0.3 0.071 11.8 0.3 1.0 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 17 Reductase_C PF14759.6 OWF36642.1 - 0.23 12.0 0.7 15 6.3 0.1 2.3 2 1 0 2 2 2 0 Reductase C-terminal Glyco_hydr_30_2 PF14587.6 OWF36643.1 - 0.00039 20.1 0.2 0.59 9.7 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 DUF1533 PF07550.11 OWF36643.1 - 0.0014 18.5 0.4 9.4 6.2 0.1 4.2 3 2 0 3 3 3 2 Protein of unknown function (DUF1533) DCAF17 PF15802.5 OWF36643.1 - 0.57 8.8 1.9 5.5 5.6 0.2 2.1 1 1 1 2 2 2 0 DDB1- and CUL4-associated factor 17 Stealth_CR4 PF17103.5 OWF36643.1 - 1.1 9.1 7.8 30 4.6 0.1 5.0 4 3 1 5 5 5 0 Stealth protein CR4, conserved region 4 Cation_efflux PF01545.21 OWF36644.1 - 5.7e-31 107.8 8.3 7.6e-31 107.4 8.3 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OWF36644.1 - 3.2e-11 43.2 0.3 5.5e-11 42.5 0.3 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Clc-like PF07062.12 OWF36644.1 - 0.13 11.7 1.1 11 5.4 0.2 2.5 2 0 0 2 2 2 0 Clc-like Transp_Tc5_C PF04236.15 OWF36644.1 - 0.16 12.3 0.9 0.41 11.0 0.9 1.6 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain 7tm_1 PF00001.21 OWF36645.1 - 9.5e-15 54.6 28.6 1.4e-14 54.0 28.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Inhibitor_I29 PF08246.12 OWF36646.1 - 3.6e-12 46.5 0.0 4.6e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) EF-hand_1 PF00036.32 OWF36647.1 - 1.1e-20 71.6 6.4 0.00022 20.6 0.3 5.7 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 OWF36647.1 - 2.4e-17 61.3 6.9 0.0027 17.5 0.2 5.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 OWF36647.1 - 2.9e-16 59.7 12.7 9.6e-09 35.6 1.2 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF36647.1 - 1.2e-13 49.9 20.1 5e-06 25.8 0.1 5.8 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 OWF36647.1 - 1.8e-10 40.5 7.1 0.0046 16.8 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF36647.1 - 0.00023 21.5 7.7 0.037 14.3 1.7 3.6 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF36647.1 - 0.00063 19.9 0.2 8.2 6.7 0.0 4.0 4 0 0 4 4 4 2 Dockerin type I domain EF-hand_4 PF12763.7 OWF36647.1 - 0.074 13.0 6.4 20 5.2 0.0 3.8 5 0 0 5 5 5 0 Cytoskeletal-regulatory complex EF hand DSL PF01414.19 OWF36648.1 - 1.5e-12 47.6 1.6 1.5e-12 47.6 1.6 2.7 2 0 0 2 2 2 1 Delta serrate ligand MNNL PF07657.13 OWF36648.1 - 1.8e-08 34.3 2.9 1.8e-08 34.3 2.9 2.5 2 0 0 2 2 2 1 N terminus of Notch ligand EGF PF00008.27 OWF36648.1 - 3.3e-06 27.3 8.6 3.3e-06 27.3 8.6 2.8 2 1 0 2 2 2 1 EGF-like domain hEGF PF12661.7 OWF36648.1 - 0.00083 19.9 6.5 0.00083 19.9 6.5 3.2 2 0 0 2 2 2 1 Human growth factor-like EGF Cys_rich_CPXG PF14255.6 OWF36648.1 - 0.011 15.6 0.8 0.03 14.2 0.8 1.7 1 0 0 1 1 1 0 Cysteine-rich CPXCG EGF_2 PF07974.13 OWF36648.1 - 0.027 14.8 9.7 0.027 14.8 9.7 3.4 2 1 0 2 2 2 0 EGF-like domain DUF4366 PF14283.6 OWF36648.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) DSL PF01414.19 OWF36649.1 - 8.9e-11 41.9 7.3 8.9e-11 41.9 7.3 2.5 1 1 1 2 2 2 1 Delta serrate ligand EGF PF00008.27 OWF36649.1 - 0.0012 19.0 11.8 0.0012 19.0 11.8 3.0 3 1 0 3 3 3 1 EGF-like domain TerD PF02342.18 OWF36649.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 TerD domain zf-C3HC4_2 PF13923.6 OWF36650.1 - 2.6e-07 30.4 10.8 2.6e-07 30.4 10.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF36650.1 - 1e-06 29.0 11.9 1e-06 29.0 11.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF36650.1 - 2.6e-06 27.2 8.7 2.6e-06 27.2 8.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF36650.1 - 8.9e-06 25.5 11.1 8.9e-06 25.5 11.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF36650.1 - 1.5e-05 24.8 10.7 1.5e-05 24.8 10.7 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF36650.1 - 3.9e-05 23.7 9.6 3.9e-05 23.7 9.6 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF36650.1 - 0.00018 21.5 11.9 0.00053 20.0 11.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-B_box PF00643.24 OWF36650.1 - 0.00042 20.4 8.5 0.00042 20.4 8.5 2.8 2 1 0 2 2 2 1 B-box zinc finger Prok-RING_4 PF14447.6 OWF36650.1 - 0.0023 17.8 10.6 0.0023 17.8 10.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF36650.1 - 0.0036 17.5 7.9 0.0036 17.5 7.9 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF36650.1 - 0.0068 16.5 7.0 0.0068 16.5 7.0 2.6 2 1 0 2 2 2 1 zinc RING finger of MSL2 NHL PF01436.21 OWF36650.1 - 0.049 13.7 0.3 3.9 7.7 0.0 3.6 4 0 0 4 4 4 0 NHL repeat Apolipoprotein PF01442.18 OWF36650.1 - 0.077 12.9 10.8 0.13 12.2 10.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PIN_2 PF10130.9 OWF36650.1 - 0.69 10.2 4.5 1.5 9.1 4.5 1.6 1 0 0 1 1 1 0 PIN domain zf-RING_4 PF14570.6 OWF36650.1 - 1.3 8.9 12.3 0.041 13.7 5.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OWF36650.1 - 2.2 8.4 8.8 5 7.2 3.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.15 OWF36650.1 - 6.2 6.3 9.0 9.4 5.7 7.2 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit GFA PF04828.14 OWF36651.1 - 0.0078 16.5 0.1 0.11 12.8 0.0 2.3 1 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 OWF36652.1 - 1.9e-70 237.3 0.0 2.3e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF36652.1 - 4.9e-31 108.0 0.0 6.6e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF36652.1 - 3.3e-08 32.9 0.1 4.8e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OWF36652.1 - 0.00045 19.6 0.3 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OWF36652.1 - 0.0093 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase HemeBinding_Shp PF11545.8 OWF36653.1 - 1.6 8.7 8.5 28 4.7 0.8 3.9 1 1 4 5 5 5 0 Cell surface heme-binding protein Shp Sulfatase PF00884.23 OWF36654.1 - 3.7e-67 226.9 0.4 4.8e-67 226.5 0.4 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF36654.1 - 0.012 15.2 0.3 0.12 11.9 0.3 2.0 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OWF36654.1 - 0.014 16.1 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Phosphoesterase PF04185.14 OWF36654.1 - 0.052 12.7 0.1 0.34 10.1 0.1 2.0 2 0 0 2 2 2 0 Phosphoesterase family His_Phos_2 PF00328.22 OWF36655.1 - 2.3e-13 50.2 1.7 3.8e-12 46.2 1.7 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BOP1NT PF08145.12 OWF36655.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain His_Phos_2 PF00328.22 OWF36656.1 - 2.4e-11 43.6 2.3 3.2e-10 39.9 2.3 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BOP1NT PF08145.12 OWF36656.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain DHO_dh PF01180.21 OWF36657.1 - 1.8e-105 352.4 0.0 2.2e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 OWF36657.1 - 0.00089 18.4 0.2 0.38 9.7 0.1 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 OWF36657.1 - 0.11 11.9 0.2 0.21 11.0 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Palm_thioest PF02089.15 OWF36658.1 - 1.2e-79 267.6 0.1 1.3e-79 267.4 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 OWF36658.1 - 0.023 14.2 0.0 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) Abhydrolase_1 PF00561.20 OWF36658.1 - 0.04 13.5 0.0 0.32 10.6 0.1 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold F-box-like PF12937.7 OWF36659.1 - 1.7e-13 50.2 0.5 5.9e-13 48.5 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF36659.1 - 5.3e-06 26.2 0.4 5.3e-06 26.2 0.4 3.5 3 0 0 3 3 3 1 F-box domain Patched PF02460.18 OWF36660.1 - 2.9e-26 91.8 41.3 5.3e-20 71.1 15.0 2.5 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 OWF36660.1 - 2.7e-13 50.0 34.7 5.4e-13 49.1 12.2 2.7 2 1 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OWF36660.1 - 4.8e-07 29.0 23.7 0.0016 17.4 15.3 2.2 2 0 0 2 2 2 2 MMPL family DUF3405 PF11885.8 OWF36660.1 - 0.092 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Lectin_C PF00059.21 OWF36661.1 - 5.8e-13 49.5 7.6 7e-13 49.2 5.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain DUF4006 PF13179.6 OWF36661.1 - 0.065 13.2 0.7 0.19 11.7 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) KAR9 PF08580.10 OWF36661.1 - 0.99 7.9 10.6 1.4 7.4 10.6 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 zf-MYND PF01753.18 OWF36663.1 - 3.8e-21 74.9 37.9 1.3e-10 41.1 11.9 2.3 2 0 0 2 2 2 2 MYND finger Meleagrin PF08189.11 OWF36663.1 - 0.061 13.0 15.6 0.33 10.7 2.2 2.6 2 0 0 2 2 2 0 Meleagrin/Cygnin family Ecl1 PF12855.7 OWF36663.1 - 4.1 8.5 14.8 7.9 7.6 1.4 2.2 1 1 1 2 2 2 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 OWF36663.1 - 4.4 7.7 29.2 14 6.1 12.9 3.1 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Mab-21 PF03281.14 OWF36664.1 - 1.4e-23 83.6 0.2 2.7e-23 82.7 0.2 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_2 PF07719.17 OWF36664.1 - 0.0024 17.9 0.0 4 7.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF36664.1 - 0.018 15.3 0.0 3.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF36664.1 - 0.036 13.9 0.0 4.2 7.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3361 PF11841.8 OWF36664.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) TPR_7 PF13176.6 OWF36664.1 - 0.084 12.9 0.0 3 8.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PIF3 PF05006.12 OWF36664.1 - 0.085 12.9 0.1 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Per os infectivity factor 3 Muraidase PF11860.8 OWF36664.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 N-acetylmuramidase Nup88 PF10168.9 OWF36665.1 - 0.1 10.4 8.3 0.3 8.8 0.5 2.3 1 1 1 2 2 2 0 Nuclear pore component WAP PF00095.21 OWF36668.1 - 0.00014 22.2 13.7 0.00034 20.9 13.7 1.7 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' PAN_4 PF14295.6 OWF36668.1 - 1.6 8.7 9.6 3.1 7.8 9.6 1.5 1 0 0 1 1 1 0 PAN domain DUF3546 PF12066.8 OWF36671.1 - 0.065 13.4 1.6 0.16 12.2 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) DED PF01335.21 OWF36673.1 - 0.0016 18.7 0.2 2.1 8.7 0.0 2.5 2 0 0 2 2 2 2 Death effector domain Ribosomal_S6e PF01092.19 OWF36674.1 - 5.9e-05 23.0 0.6 0.002 18.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S6e KMP11 PF03037.16 OWF36675.1 - 0.014 16.1 6.1 0.019 15.7 6.1 1.2 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 VWD PF00094.25 OWF36676.1 - 2.3e-05 24.7 0.1 6.4e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_Tenascin PF18720.1 OWF36676.1 - 0.0015 18.5 8.4 0.0015 18.5 8.4 3.6 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 OWF36676.1 - 0.0048 17.2 16.2 0.0048 17.2 16.2 5.0 5 1 0 5 5 5 1 EGF-like domain SSURE PF11966.8 OWF36676.1 - 0.26 11.1 0.7 5.2 6.9 0.2 2.9 3 0 0 3 3 3 0 Fibronectin-binding repeat 7tm_1 PF00001.21 OWF36677.1 - 9e-32 110.4 6.1 1.6e-31 109.6 6.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF36677.1 - 2.3e-06 27.5 7.8 7e-06 25.9 7.8 1.8 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF36677.1 - 2.5e-05 23.8 7.0 4.6e-05 22.9 7.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF36679.1 - 8.4e-07 28.6 14.7 1.1e-06 28.2 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TNF PF00229.18 OWF36680.1 - 1.1e-05 25.4 0.2 0.00012 22.0 0.1 2.4 2 1 0 2 2 2 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF36680.1 - 0.0053 17.0 0.2 0.012 15.8 0.2 1.6 1 0 0 1 1 1 1 C1q domain Cadherin_C_2 PF16492.5 OWF36680.1 - 0.054 14.2 0.0 0.43 11.4 0.0 2.4 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF3328 PF11807.8 OWF36680.1 - 0.062 13.1 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) TNF PF00229.18 OWF36683.1 - 9.1e-06 25.6 0.1 3.4e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF36683.1 - 0.0012 19.0 0.0 0.0044 17.2 0.0 1.9 1 0 0 1 1 1 1 C1q domain Toxin_7 PF05980.12 OWF36683.1 - 0.023 14.9 1.4 0.061 13.6 1.4 1.7 1 0 0 1 1 1 0 Toxin 7 Conotoxin PF02950.17 OWF36683.1 - 0.52 11.4 5.3 0.13 13.3 1.4 2.1 2 0 0 2 2 2 0 Conotoxin TDP43_N PF18694.1 OWF36684.1 - 9.9e-34 115.0 0.0 1.8e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 OWF36684.1 - 4e-26 90.6 0.1 5.8e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF36684.1 - 5.4e-05 23.2 0.1 0.12 12.6 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif RL PF17797.1 OWF36684.1 - 0.0069 16.3 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 RL domain Nup35_RRM_2 PF14605.6 OWF36684.1 - 0.04 13.9 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1242 PF06842.12 OWF36685.1 - 0.0023 17.7 10.9 63 3.5 0.1 7.5 1 1 7 8 8 8 0 Protein of unknown function (DUF1242) Antimicrobial_1 PF08018.11 OWF36685.1 - 0.0046 17.1 12.6 2.7e+02 1.8 0.0 8.3 9 0 0 9 9 9 0 Frog antimicrobial peptide Wyosine_form PF08608.12 OWF36685.1 - 0.0093 16.3 15.7 1.4e+02 2.9 0.0 8.2 1 1 8 9 9 9 0 Wyosine base formation PNRC PF15365.6 OWF36685.1 - 7.3 6.5 15.0 4.7e+02 0.8 0.0 7.7 9 0 0 9 9 9 0 Proline-rich nuclear receptor coactivator motif Antimicrobial_1 PF08018.11 OWF36686.1 - 0.0088 16.2 21.9 4.6e+02 1.1 0.0 12.1 14 0 0 14 14 14 0 Frog antimicrobial peptide Wyosine_form PF08608.12 OWF36686.1 - 0.062 13.7 28.5 1.6e+02 2.8 0.2 12.0 1 1 12 13 13 13 0 Wyosine base formation DUF1242 PF06842.12 OWF36686.1 - 0.098 12.5 24.6 77 3.2 0.4 10.5 3 1 4 7 7 7 0 Protein of unknown function (DUF1242) ETC_C1_NDUFA5 PF04716.14 OWF36687.1 - 2.5e-24 84.8 0.2 3.7e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Crystall PF00030.19 OWF36688.1 - 1.9e-29 101.7 1.6 5.3e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.10 OWF36688.1 - 0.0025 17.9 0.2 0.54 10.5 0.0 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin SDF PF00375.18 OWF36689.1 - 2.2e-84 283.7 34.8 2.5e-84 283.6 34.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family YfkB PF08756.10 OWF36690.1 - 8.6e-06 25.6 0.4 0.97 9.2 0.0 4.4 1 1 3 5 5 5 2 YfkB-like domain DNA_ligase_IV PF11411.8 OWF36690.1 - 0.0028 17.8 2.9 44 4.3 0.0 6.6 3 3 5 8 8 8 0 DNA ligase IV RRM_1 PF00076.22 OWF36690.1 - 0.0033 17.2 1.4 12 5.8 0.0 5.4 3 3 2 7 7 7 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3158 PF11358.8 OWF36690.1 - 0.0059 16.3 0.7 16 5.2 0.0 3.9 1 1 1 3 3 3 1 Protein of unknown function (DUF3158) Knl1_RWD_C PF18210.1 OWF36690.1 - 0.0092 16.4 5.9 0.73 10.3 0.4 4.3 1 1 5 6 6 6 2 Knl1 RWD C-terminal domain HEPN_RiboL-PSP PF18735.1 OWF36690.1 - 0.024 14.6 16.0 1.9 8.3 5.6 2.7 1 1 1 2 2 2 0 RiboL-PSP-HEPN Sulfotransfer_2 PF03567.14 OWF36691.1 - 1.9e-24 87.0 5.8 3.5e-21 76.3 0.8 2.4 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF36692.1 - 3.6e-10 40.2 0.2 5.8e-07 29.7 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF36693.1 - 5.5e-22 78.9 0.1 1.5e-17 64.4 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Cadherin_C_2 PF16492.5 OWF36693.1 - 0.11 13.2 0.0 0.3 11.9 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF5461 PF17545.2 OWF36694.1 - 0.093 13.0 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5461) Glyco_transf_11 PF01531.16 OWF36695.1 - 4.2e-08 32.8 0.1 4.9e-08 32.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Scramblase PF03803.15 OWF36696.1 - 6.9e-47 159.6 0.0 2.2e-46 157.9 0.1 1.6 1 1 1 2 2 2 2 Scramblase NHL PF01436.21 OWF36697.1 - 4.9e-05 23.1 1.0 0.12 12.4 0.1 4.4 4 0 0 4 4 4 2 NHL repeat NHL PF01436.21 OWF36698.1 - 0.00036 20.4 3.7 1.4 9.1 0.0 5.0 5 0 0 5 5 5 2 NHL repeat DUF3659 PF12396.8 OWF36698.1 - 0.0099 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) SGL PF08450.12 OWF36698.1 - 0.037 13.6 0.0 1.3 8.5 0.0 2.4 1 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region zf_Hakai PF18408.1 OWF36698.1 - 1.5 8.5 4.9 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain C1q PF00386.21 OWF36699.1 - 6.6e-21 74.8 1.2 9.7e-21 74.3 1.2 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF36699.1 - 0.083 12.8 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 BclA C-terminal domain NHL PF01436.21 OWF36700.1 - 0.0024 17.8 0.6 0.083 13.0 0.1 3.7 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.11 OWF36700.1 - 0.027 14.6 0.0 49 4.6 0.0 4.0 3 0 0 3 3 3 0 Two component regulator propeller Methyltransf_FA PF12248.8 OWF36700.1 - 0.094 13.0 0.1 1.7 9.0 0.0 2.7 3 0 0 3 3 3 0 Farnesoic acid 0-methyl transferase NHL PF01436.21 OWF36701.1 - 7.9e-05 22.5 1.5 0.18 11.9 0.0 3.6 4 0 0 4 4 4 2 NHL repeat DUF3659 PF12396.8 OWF36701.1 - 0.16 11.9 0.0 26 4.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) TFA2_Winged_2 PF18121.1 OWF36703.1 - 0.00021 20.9 0.2 0.37 10.5 0.1 2.9 2 0 0 2 2 2 2 TFA2 Winged helix domain 2 DUF3510 PF12022.8 OWF36703.1 - 0.11 12.9 1.5 1.7 9.0 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Sec8_exocyst PF04048.14 OWF36703.1 - 0.23 11.3 4.0 0.35 10.7 0.1 2.8 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain Prefoldin PF02996.17 OWF36703.1 - 0.26 11.2 7.4 1 9.3 0.1 3.6 4 1 0 4 4 4 0 Prefoldin subunit DNA_repr_REX1B PF14966.6 OWF36703.1 - 0.31 11.7 5.4 0.28 11.9 1.0 3.0 3 1 0 3 3 3 0 DNA repair REX1-B GARP PF16731.5 OWF36703.1 - 4 7.1 7.1 0.69 9.6 0.3 2.7 3 0 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma PMG PF05287.12 OWF36704.1 - 0.86 9.6 36.2 0.1 12.6 29.5 2.1 1 1 1 2 2 2 0 PMG protein Keratin_B2 PF01500.17 OWF36704.1 - 0.96 9.4 20.5 2e+02 1.9 20.5 2.3 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein 7TM_GPCR_Srw PF10324.9 OWF36705.1 - 4.5e-09 36.0 17.4 6.3e-06 25.7 5.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF36705.1 - 8.2e-09 35.2 18.3 1.4e-08 34.4 18.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Saf_2TM PF18303.1 OWF36705.1 - 0.17 11.5 2.5 1.9 8.1 0.1 2.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Gemini_mov PF01708.16 OWF36705.1 - 0.34 10.7 5.1 3.4 7.5 0.2 3.1 3 1 0 3 3 3 0 Geminivirus putative movement protein DUF4389 PF14333.6 OWF36705.1 - 0.41 10.6 0.1 0.41 10.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) SOR_SNZ PF01680.17 OWF36707.1 - 1.8e-106 354.5 5.7 1.8e-106 354.5 5.7 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 OWF36707.1 - 1.5e-09 37.6 1.8 6.8e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 OWF36707.1 - 0.013 15.0 0.1 0.098 12.1 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 OWF36707.1 - 0.018 14.2 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 OWF36707.1 - 0.024 14.1 4.0 0.16 11.3 0.0 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase NanE PF04131.14 OWF36707.1 - 0.028 13.6 1.3 0.96 8.6 0.0 2.6 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 OWF36707.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SNO PF01174.19 OWF36708.1 - 3.3e-46 157.5 0.0 1.5e-45 155.4 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 OWF36708.1 - 1.5e-10 41.0 0.0 1.2e-09 38.0 0.0 2.3 1 1 1 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 OWF36708.1 - 8.6e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family S51 BPL_N PF09825.9 OWF36708.1 - 0.039 13.0 0.0 0.12 11.4 0.0 1.7 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal ThiJ_like PF17124.5 OWF36708.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 OWF36708.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family TSP_1 PF00090.19 OWF36709.1 - 1.8e-12 47.2 10.2 2.1e-12 47.0 8.3 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF36709.1 - 7.9e-12 45.6 0.4 2.6e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 OWF36709.1 - 2.4e-08 34.2 0.1 7.5e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF36709.1 - 5.6e-07 29.6 0.0 1.9e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain CarboxypepD_reg PF13620.6 OWF36709.1 - 0.00012 22.2 0.5 0.0028 17.9 0.0 3.3 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain V-set PF07686.17 OWF36709.1 - 0.00038 20.6 1.2 0.0054 16.9 0.2 3.0 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF36709.1 - 0.0022 18.2 0.1 0.0051 17.0 0.1 1.5 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain CarbopepD_reg_2 PF13715.6 OWF36709.1 - 0.0055 16.7 0.6 0.024 14.6 0.1 2.4 3 0 0 3 3 3 1 CarboxypepD_reg-like domain ig PF00047.25 OWF36709.1 - 0.064 13.4 1.3 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain Podoplanin PF05808.11 OWF36709.1 - 0.82 9.8 3.9 1.6 8.8 3.9 1.4 1 0 0 1 1 1 0 Podoplanin Adeno_E3_CR1 PF02440.15 OWF36709.1 - 2.4 8.0 6.5 0.51 10.1 0.1 2.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Ub-RnfH PF03658.14 OWF36710.1 - 0.01 16.2 22.6 2.8 8.4 0.7 7.9 3 2 5 8 8 8 0 RnfH family Ubiquitin Bactofilin PF04519.13 OWF36710.1 - 0.093 13.0 32.4 0.43 10.9 4.1 5.1 2 2 1 4 4 4 0 Polymer-forming cytoskeletal Kelch_6 PF13964.6 OWF36710.1 - 0.1 12.9 30.9 14 6.1 0.2 10.7 4 2 5 9 9 9 0 Kelch motif DUF4264 PF14084.6 OWF36710.1 - 1.3 8.7 14.8 8.5 6.1 0.1 7.4 7 0 0 7 7 7 0 Protein of unknown function (DUF4264) Glyoxalase_2 PF12681.7 OWF36711.1 - 0.0022 17.9 5.4 0.6 10.1 0.5 3.0 1 1 1 2 2 2 2 Glyoxalase-like domain GIT1_C PF12205.8 OWF36711.1 - 0.0082 16.3 3.0 5.7 7.1 0.1 3.9 1 1 5 6 6 6 1 G protein-coupled receptor kinase-interacting protein 1 C term P4Ha_N PF08336.11 OWF36711.1 - 0.011 15.8 0.2 2 8.4 0.1 2.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NAD_binding_10 PF13460.6 OWF36711.1 - 0.035 14.0 4.2 2.3 8.0 0.3 3.1 1 1 1 2 2 2 0 NAD(P)H-binding T4SS PF07996.11 OWF36711.1 - 0.11 12.8 0.7 0.2 12.1 0.7 1.5 1 1 0 1 1 1 0 Type IV secretion system proteins WSD PF15613.6 OWF36711.1 - 0.13 12.8 0.2 12 6.5 0.0 2.7 1 1 1 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Syntaxin-6_N PF09177.11 OWF36711.1 - 0.17 12.4 10.4 5 7.7 0.5 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal FPP PF05911.11 OWF36711.1 - 0.23 9.6 7.9 0.26 9.4 7.9 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Kelch_1 PF01344.25 OWF36711.1 - 0.23 11.1 37.8 3.1 7.5 0.5 9.1 6 4 2 8 8 8 0 Kelch motif Lipoprotein_2 PF00921.17 OWF36711.1 - 0.84 9.1 9.8 2.9 7.4 4.0 2.2 1 1 1 2 2 2 0 Borrelia lipoprotein NolX PF05819.11 OWF36711.1 - 1.3 8.3 3.3 35 3.6 0.1 2.9 1 1 1 3 3 3 0 NolX protein GIT1_C PF12205.8 OWF36712.1 - 2.8e-05 24.2 1.5 0.77 9.9 0.0 4.5 1 1 4 5 5 5 2 G protein-coupled receptor kinase-interacting protein 1 C term SAM_LFY PF01698.16 OWF36712.1 - 0.0033 17.3 6.3 1.6 8.7 0.1 4.8 1 1 3 4 4 4 2 Floricaula / Leafy protein SAM domain Rad60-SLD PF11976.8 OWF36712.1 - 0.0052 16.6 1.5 4.6 7.2 0.0 4.9 3 2 2 5 5 5 1 Ubiquitin-2 like Rad60 SUMO-like DUF4807 PF16065.5 OWF36712.1 - 0.0057 16.3 0.0 18 5.0 0.0 4.1 2 2 3 5 5 5 0 Domain of unknown function (DUF4807) Kelch_1 PF01344.25 OWF36712.1 - 0.0065 16.0 50.3 3.5 7.3 0.7 12.5 6 5 4 10 10 10 1 Kelch motif Glyoxalase_2 PF12681.7 OWF36712.1 - 0.0069 16.3 6.7 5.1 7.1 0.3 4.0 1 1 4 5 5 5 1 Glyoxalase-like domain T4SS PF07996.11 OWF36712.1 - 0.015 15.7 0.4 1.4 9.3 0.1 2.3 1 1 1 2 2 2 0 Type IV secretion system proteins DUF713 PF05218.14 OWF36712.1 - 0.079 12.7 5.1 0.19 11.5 1.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF713) STN1_2 PF09170.10 OWF36712.1 - 0.15 12.3 6.5 5.9 7.1 0.2 3.6 1 1 2 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 TAtT PF16811.5 OWF36712.1 - 0.18 11.1 0.1 20 4.4 0.0 2.6 1 1 1 3 3 3 0 TRAP transporter T-component ATP13 PF12921.7 OWF36712.1 - 0.22 11.4 9.2 4.5 7.2 1.0 3.9 1 1 0 3 3 3 0 Mitochondrial ATPase expression RPA_C PF08784.11 OWF36712.1 - 0.28 11.8 17.5 4.8 7.9 0.4 6.3 3 2 1 5 5 5 0 Replication protein A C terminal DUF948 PF06103.11 OWF36712.1 - 1.2 9.5 13.6 2.9e+02 1.8 0.3 4.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ATP-synt_D PF01813.17 OWF36712.1 - 5 6.9 11.3 5.4 6.8 1.1 2.9 1 1 2 3 3 3 0 ATP synthase subunit D Melibiase_2 PF16499.5 OWF36712.1 - 8 5.5 14.3 17 4.4 1.1 3.3 1 1 2 3 3 3 0 Alpha galactosidase A DUF4402 PF14352.6 OWF36713.1 - 0.0057 17.3 8.9 14 6.4 0.1 4.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4402) DUF4744 PF15918.5 OWF36713.1 - 0.0062 17.4 14.4 3.7 8.4 1.0 3.8 1 1 6 7 7 7 6 Domain of unknown function (DUF4744) eIF-4B PF06273.11 OWF36713.1 - 0.013 14.6 11.1 6.5 5.7 0.9 5.1 1 1 5 6 6 6 0 Plant specific eukaryotic initiation factor 4B DUF1213 PF06740.12 OWF36713.1 - 0.072 13.7 15.9 5.2e+02 1.3 0.0 7.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1213) Flg_new PF09479.10 OWF36713.1 - 0.21 11.8 3.4 4.2e+02 1.2 0.0 4.9 1 1 8 10 10 10 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) HCMVantigenic_N PF12154.8 OWF36713.1 - 2.3 8.4 40.8 1.7e+02 2.4 0.2 12.1 12 1 1 13 13 13 0 Glycoprotein B N-terminal antigenic domain of HCMV DUF1664 PF07889.12 OWF36714.1 - 2.6e-11 43.6 4.0 0.011 15.8 0.4 4.5 2 2 1 3 3 3 3 Protein of unknown function (DUF1664) HsbA PF12296.8 OWF36714.1 - 2.7e-10 40.7 0.3 0.0094 16.4 0.0 3.9 2 1 1 3 3 3 2 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 OWF36714.1 - 4.8e-09 36.4 13.0 0.00016 21.7 4.8 3.0 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 OWF36714.1 - 1.1e-08 35.0 6.5 0.0017 18.3 0.4 3.1 2 1 1 3 3 3 3 Sec34-like family KxDL PF10241.9 OWF36714.1 - 1.7e-08 34.6 15.4 0.06 13.6 0.6 5.6 2 2 3 5 5 5 2 Uncharacterized conserved protein PI_PP_I PF18363.1 OWF36714.1 - 3.8e-08 33.4 9.3 0.052 13.7 0.5 4.8 2 2 1 3 3 3 2 Phosphoinositide phosphatase insertion domain EzrA PF06160.12 OWF36714.1 - 4.3e-08 31.8 5.6 5.7e-05 21.5 1.9 2.4 2 1 0 2 2 2 2 Septation ring formation regulator, EzrA Occludin_ELL PF07303.13 OWF36714.1 - 1.6e-07 32.0 3.9 0.32 11.8 0.0 4.2 2 2 2 4 4 4 2 Occludin homology domain Laminin_II PF06009.12 OWF36714.1 - 2.2e-07 31.0 2.4 0.13 12.3 0.2 3.7 2 2 1 3 3 3 3 Laminin Domain II RmuC PF02646.16 OWF36714.1 - 3.3e-07 29.7 0.3 0.21 10.7 0.1 3.3 2 1 1 3 3 3 2 RmuC family APG17 PF04108.12 OWF36714.1 - 8.3e-07 28.5 2.8 0.022 13.9 0.1 2.9 2 1 1 3 3 3 2 Autophagy protein Apg17 DUF2408 PF10303.9 OWF36714.1 - 1.1e-06 29.2 8.4 0.019 15.5 0.8 4.4 1 1 2 3 3 3 2 Protein of unknown function (DUF2408) Tweety PF04906.13 OWF36714.1 - 2.6e-06 26.4 2.9 0.066 11.9 0.2 3.0 2 1 1 3 3 3 2 Tweety Syntaxin PF00804.25 OWF36714.1 - 4.6e-06 26.4 2.1 0.014 15.1 0.3 2.7 2 1 0 2 2 2 2 Syntaxin PI3K_P85_iSH2 PF16454.5 OWF36714.1 - 7.7e-06 25.6 5.1 0.038 13.6 0.2 3.2 2 1 0 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF948 PF06103.11 OWF36714.1 - 1.8e-05 24.9 4.6 1.1 9.5 0.1 3.6 2 2 1 3 3 3 2 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 OWF36714.1 - 3.2e-05 23.7 0.7 0.91 9.3 0.3 3.5 2 1 1 3 3 3 2 Spindle and kinetochore-associated protein 2 YabA PF06156.13 OWF36714.1 - 4.4e-05 24.0 1.6 2.3 8.9 0.1 3.3 2 1 1 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OWF36714.1 - 5.4e-05 23.2 0.0 0.93 9.5 0.0 2.9 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF713 PF05218.14 OWF36714.1 - 8.3e-05 22.4 1.1 0.95 9.2 0.1 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF713) IFT57 PF10498.9 OWF36714.1 - 0.00011 21.3 5.0 0.013 14.5 1.1 2.2 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 Bep_C_terminal PF17841.1 OWF36714.1 - 0.00013 22.1 0.0 10 6.4 0.0 4.0 2 1 3 5 5 5 0 BID domain of Bartonella effector protein (Bep) COG6 PF06419.11 OWF36714.1 - 0.00015 20.1 2.5 0.2 9.8 0.1 3.1 2 1 1 3 3 3 1 Conserved oligomeric complex COG6 FlaC_arch PF05377.11 OWF36714.1 - 0.00016 22.0 0.0 13 6.2 0.0 4.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 OWF36714.1 - 0.00019 20.4 0.1 0.18 10.7 0.0 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein TACC_C PF05010.14 OWF36714.1 - 0.00024 21.0 0.0 0.84 9.4 0.0 3.1 2 1 1 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SesA PF17107.5 OWF36714.1 - 0.00039 20.6 3.3 1.6 8.9 0.3 4.3 2 2 2 4 4 4 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 OWF36714.1 - 0.00039 20.8 8.8 1 9.9 0.6 3.7 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Plasmid_RAQPRD PF09686.10 OWF36714.1 - 0.00041 20.5 17.1 0.19 11.9 1.8 6.1 2 2 1 3 3 3 1 Plasmid protein of unknown function (Plasmid_RAQPRD) MscS_porin PF12795.7 OWF36714.1 - 0.00043 19.9 0.2 0.046 13.3 0.1 2.5 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain DHR10 PF18595.1 OWF36714.1 - 0.00077 19.5 0.1 4.6 7.3 0.0 3.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Med16 PF11635.8 OWF36714.1 - 0.00096 17.2 3.0 1.1 7.0 0.0 3.2 2 1 1 3 3 3 1 Mediator complex subunit 16 Laminin_I PF06008.14 OWF36714.1 - 0.0011 18.7 1.5 0.79 9.4 0.3 2.1 2 0 0 2 2 2 2 Laminin Domain I COG2 PF06148.11 OWF36714.1 - 0.0012 18.9 1.7 1.4 9.0 0.3 3.1 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 EMP24_GP25L PF01105.24 OWF36714.1 - 0.0013 18.7 10.0 2.9 7.8 1.0 4.9 2 2 2 4 4 4 0 emp24/gp25L/p24 family/GOLD DLP_helical PF18709.1 OWF36714.1 - 0.0016 17.7 1.8 1 8.5 0.1 2.8 2 1 1 3 3 3 1 Dynamin-like helical domain GCN5L1 PF06320.13 OWF36714.1 - 0.0019 18.3 4.6 4.4 7.5 0.2 4.6 2 2 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF5089 PF17002.5 OWF36714.1 - 0.0021 18.0 0.7 4.2 7.2 0.1 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5089) DegS PF05384.11 OWF36714.1 - 0.0039 16.7 2.6 6.5 6.2 0.1 3.1 2 1 1 3 3 3 0 Sensor protein DegS ERF PF04404.12 OWF36714.1 - 0.0065 16.3 0.2 6.5 6.6 0.0 3.4 2 1 1 3 3 3 0 ERF superfamily Tup_N PF08581.10 OWF36714.1 - 0.007 16.6 9.1 1.1 9.6 0.5 3.8 2 1 1 3 3 3 1 Tup N-terminal Nsp1_C PF05064.13 OWF36714.1 - 0.0072 16.1 0.2 31 4.4 0.0 3.5 2 1 0 3 3 3 0 Nsp1-like C-terminal region TMPIT PF07851.13 OWF36714.1 - 0.0075 15.6 0.3 3.6 6.8 0.1 2.4 2 1 0 2 2 2 0 TMPIT-like protein Prominin PF05478.11 OWF36714.1 - 0.0087 14.1 6.6 0.093 10.7 1.3 2.1 2 0 0 2 2 2 2 Prominin IFN-gamma PF00714.17 OWF36714.1 - 0.011 15.6 6.1 19 5.1 0.1 4.7 2 2 3 5 5 5 0 Interferon gamma DUF16 PF01519.16 OWF36714.1 - 0.011 16.2 3.4 3.4 8.2 0.1 3.4 2 2 1 3 3 3 0 Protein of unknown function DUF16 MIP-T3_C PF17749.1 OWF36714.1 - 0.012 15.6 0.2 4.2 7.3 0.0 3.1 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region CK2S PF15011.6 OWF36714.1 - 0.014 15.3 0.1 13 5.6 0.0 3.4 2 1 2 4 4 4 0 Casein Kinase 2 substrate Leu_zip PF15294.6 OWF36714.1 - 0.015 14.9 0.6 3.3 7.2 0.1 2.4 2 1 1 3 3 3 0 Leucine zipper APG6_N PF17675.1 OWF36714.1 - 0.016 15.8 0.0 3.6 8.1 0.0 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region WEMBL PF05701.11 OWF36714.1 - 0.016 13.9 0.0 0.51 9.0 0.0 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light V-ATPase_C PF03223.15 OWF36714.1 - 0.017 14.6 4.0 3.5 6.9 0.1 3.1 2 1 1 3 3 3 0 V-ATPase subunit C DUF148 PF02520.17 OWF36714.1 - 0.017 15.2 6.7 9.3 6.4 0.1 4.1 2 2 1 3 3 3 0 Domain of unknown function DUF148 DUF4709 PF15821.5 OWF36714.1 - 0.023 15.0 4.8 0.72 10.2 0.5 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4709) WXG100 PF06013.12 OWF36714.1 - 0.035 14.3 0.0 46 4.4 0.0 4.3 2 2 1 4 4 4 0 Proteins of 100 residues with WXG Sec3_C PF09763.9 OWF36714.1 - 0.035 12.5 3.2 0.22 9.9 0.2 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 Ly49 PF08391.10 OWF36714.1 - 0.042 14.2 3.9 0.29 11.5 0.2 2.7 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Flagellin_N PF00669.20 OWF36714.1 - 0.051 13.7 1.1 4.4 7.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region SLATT_1 PF18181.1 OWF36714.1 - 0.052 13.5 2.4 5.1 7.1 0.0 4.1 2 2 3 5 5 5 0 SMODS and SLOG-associating 2TM effector domain 1 DUF1515 PF07439.11 OWF36714.1 - 0.058 13.4 5.5 21 5.2 0.5 4.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1515) DUF489 PF04356.12 OWF36714.1 - 0.083 12.9 5.8 9.9 6.1 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF489) Fzo_mitofusin PF04799.13 OWF36714.1 - 0.097 12.2 0.7 3.3 7.2 0.1 2.5 2 1 1 3 3 3 0 fzo-like conserved region Fib_alpha PF08702.10 OWF36714.1 - 0.11 12.6 9.5 4.1 7.6 0.4 3.8 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 OWF36714.1 - 0.14 12.3 0.1 4.7 7.3 0.0 2.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase ArAE_2 PF10334.9 OWF36714.1 - 0.15 11.9 1.3 0.56 10.0 0.3 2.2 2 1 0 2 2 2 0 Aromatic acid exporter family member 2 Snapin_Pallidin PF14712.6 OWF36714.1 - 0.22 11.9 6.3 8.8 6.8 0.4 3.1 2 1 1 3 3 3 0 Snapin/Pallidin DUF4201 PF13870.6 OWF36714.1 - 0.23 11.2 12.0 1.8 8.2 2.1 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) zf-C4H2 PF10146.9 OWF36714.1 - 0.24 11.7 17.7 0.28 11.5 3.4 3.0 1 1 2 3 3 3 0 Zinc finger-containing protein DUF3209 PF11483.8 OWF36714.1 - 0.28 11.7 18.7 15 6.0 0.1 5.4 2 2 4 6 6 6 0 Protein of unknown function (DUF3209) Herpes_U30 PF04523.13 OWF36714.1 - 0.32 8.8 6.4 3.8 5.3 0.3 2.8 2 1 0 2 2 2 0 Herpes virus tegument protein U30 XhlA PF10779.9 OWF36714.1 - 0.38 11.0 25.5 7.3 6.9 1.8 4.9 2 2 2 4 4 4 0 Haemolysin XhlA PA28_alpha PF02251.18 OWF36714.1 - 0.52 10.4 13.4 98 3.1 0.1 7.4 2 2 6 9 9 9 0 Proteasome activator pa28 alpha subunit HTH_11 PF08279.12 OWF36714.1 - 0.56 10.2 23.4 34 4.5 0.4 8.4 2 2 6 8 8 7 0 HTH domain Dynamitin PF04912.14 OWF36714.1 - 1.1 8.5 3.9 14 4.9 0.2 2.3 2 1 0 2 2 2 0 Dynamitin Syntaxin_2 PF14523.6 OWF36714.1 - 1.3 9.4 12.3 5.2 7.5 2.5 2.9 2 1 0 2 2 2 0 Syntaxin-like protein Col_cuticle_N PF01484.17 OWF36714.1 - 2 8.6 17.1 61 3.8 0.1 7.8 4 3 2 7 7 7 0 Nematode cuticle collagen N-terminal domain TssO PF17561.2 OWF36714.1 - 2 8.5 8.4 14 5.8 1.8 3.3 2 1 1 3 3 3 0 Type VI secretion system, TssO DUF1601 PF07671.11 OWF36714.1 - 2.6 8.0 29.5 28 4.7 0.1 10.2 6 3 0 6 6 6 0 Protein of unknown function (DUF1601) Med30 PF11315.8 OWF36714.1 - 2.6 8.2 9.4 13 6.0 1.5 3.4 2 2 1 3 3 3 0 Mediator complex subunit 30 LXG PF04740.12 OWF36714.1 - 3.9 7.1 9.1 7 6.3 0.9 2.9 2 2 1 3 3 3 0 LXG domain of WXG superfamily B2 PF11473.8 OWF36714.1 - 6.1 6.7 12.9 16 5.4 0.1 5.2 2 2 2 4 4 4 0 RNA binding protein B2 DUF2951 PF11166.8 OWF36714.1 - 7.6 6.8 8.3 13 6.0 0.4 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) VWC PF00093.18 OWF36716.1 - 2.6e-14 53.3 41.6 1.9e-07 31.3 12.2 4.1 3 1 1 4 4 4 3 von Willebrand factor type C domain Pacifastin_I PF05375.13 OWF36716.1 - 7.3e-06 25.6 28.6 0.00047 19.8 1.8 3.9 3 1 1 4 4 4 3 Pacifastin inhibitor (LCMII) TILa PF12714.7 OWF36716.1 - 0.042 13.8 7.6 0.042 13.8 7.6 4.7 2 1 1 4 4 4 0 TILa domain VWC PF00093.18 OWF36717.1 - 3.3e-08 33.7 12.0 4e-08 33.5 12.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type C domain Pacifastin_I PF05375.13 OWF36717.1 - 0.0037 17.0 8.2 0.0038 16.9 7.0 1.6 2 0 0 2 2 2 1 Pacifastin inhibitor (LCMII) Amnionless PF14828.6 OWF36717.1 - 0.78 8.5 13.2 0.85 8.4 13.2 1.0 1 0 0 1 1 1 0 Amnionless V-ATPase_C PF03223.15 OWF36718.1 - 5.4e-140 467.0 3.2 6e-140 466.8 3.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C IL5 PF02025.15 OWF36718.1 - 0.057 13.7 0.3 0.17 12.2 0.3 1.8 1 0 0 1 1 1 0 Interleukin 5 FliD_N PF02465.18 OWF36718.1 - 0.087 13.5 0.4 0.36 11.5 0.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus GAT PF03127.14 OWF36718.1 - 0.11 12.8 0.6 0.86 9.9 0.0 2.7 3 0 0 3 3 3 0 GAT domain MFS_1 PF07690.16 OWF36719.1 - 9.5e-26 90.5 40.7 1.8e-21 76.5 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Baculo_PEP_C PF04513.12 OWF36720.1 - 9e-11 42.0 8.3 7e-06 26.1 3.7 2.9 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus SCAPER_N PF16501.5 OWF36720.1 - 1.6e-09 37.6 15.2 0.054 13.5 0.8 7.5 1 1 4 5 5 5 2 S phase cyclin A-associated protein in the endoplasmic reticulum Syntaxin-6_N PF09177.11 OWF36720.1 - 1.9e-08 34.7 11.4 0.31 11.6 0.2 4.7 1 1 2 3 3 3 2 Syntaxin 6, N-terminal DUF948 PF06103.11 OWF36720.1 - 3.6e-08 33.6 0.3 0.033 14.4 0.1 3.5 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 OWF36720.1 - 2e-07 31.0 0.0 0.0072 16.1 0.0 2.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain GCN5L1 PF06320.13 OWF36720.1 - 9.8e-07 28.9 4.2 0.099 12.8 0.1 3.1 1 1 1 3 3 3 2 GCN5-like protein 1 (GCN5L1) RmuC PF02646.16 OWF36720.1 - 1.6e-06 27.5 6.8 0.058 12.5 1.6 3.2 1 1 2 3 3 3 3 RmuC family DASH_Dad1 PF08649.10 OWF36720.1 - 1.8e-06 28.0 6.5 6.1 7.1 0.1 5.7 1 1 3 6 6 6 0 DASH complex subunit Dad1 FlaC_arch PF05377.11 OWF36720.1 - 1.9e-06 28.1 19.6 0.14 12.5 1.4 4.5 1 1 5 6 6 6 4 Flagella accessory protein C (FlaC) Syntaxin PF00804.25 OWF36720.1 - 2e-06 27.6 8.9 0.013 15.2 0.6 2.9 1 1 0 2 2 2 1 Syntaxin WXG100 PF06013.12 OWF36720.1 - 2.9e-06 27.4 3.7 1.8 8.8 0.1 5.1 1 1 3 4 4 4 0 Proteins of 100 residues with WXG DegS PF05384.11 OWF36720.1 - 3.9e-06 26.4 6.7 0.33 10.4 0.3 3.1 1 1 2 3 3 3 3 Sensor protein DegS SesA PF17107.5 OWF36720.1 - 5.4e-06 26.6 5.9 0.0027 17.9 1.3 2.5 1 1 1 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases SKA2 PF16740.5 OWF36720.1 - 1.2e-05 25.0 8.7 0.036 13.9 2.7 3.6 1 1 2 3 3 3 2 Spindle and kinetochore-associated protein 2 DUF3963 PF13124.6 OWF36720.1 - 1.4e-05 24.9 18.5 8.7 6.4 0.1 9.1 1 1 4 9 9 9 0 Protein of unknown function (DUF3963) YkyA PF10368.9 OWF36720.1 - 1.6e-05 24.6 20.6 0.013 15.2 9.3 2.2 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein FH2 PF02181.23 OWF36720.1 - 2e-05 23.9 9.0 0.00016 21.0 5.2 2.2 1 1 1 2 2 2 2 Formin Homology 2 Domain DASH_Duo1 PF08651.10 OWF36720.1 - 2.3e-05 24.0 9.9 0.47 10.3 0.3 4.4 1 1 5 6 6 6 2 DASH complex subunit Duo1 DUF812 PF05667.11 OWF36720.1 - 2.5e-05 23.4 5.2 3.9e-05 22.7 5.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Laminin_II PF06009.12 OWF36720.1 - 3.6e-05 23.8 9.8 0.22 11.6 9.8 2.8 1 1 0 1 1 1 1 Laminin Domain II COG5 PF10392.9 OWF36720.1 - 4.5e-05 23.6 15.7 0.044 14.0 3.7 2.8 1 1 1 2 2 2 2 Golgi transport complex subunit 5 DUF1664 PF07889.12 OWF36720.1 - 4.8e-05 23.4 9.5 0.053 13.6 1.3 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) EzrA PF06160.12 OWF36720.1 - 5.6e-05 21.5 21.8 0.00015 20.1 21.8 1.6 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA TMPIT PF07851.13 OWF36720.1 - 5.8e-05 22.5 8.2 0.017 14.4 2.8 2.1 1 1 1 2 2 2 2 TMPIT-like protein Spc7 PF08317.11 OWF36720.1 - 6.4e-05 22.0 19.2 0.00061 18.8 5.2 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein YabA PF06156.13 OWF36720.1 - 9.1e-05 23.0 9.1 0.12 13.0 1.4 3.8 1 1 3 4 4 4 2 Initiation control protein YabA AAA_13 PF13166.6 OWF36720.1 - 0.00013 20.8 8.1 0.00016 20.5 8.1 1.1 1 0 0 1 1 1 1 AAA domain DUF745 PF05335.13 OWF36720.1 - 0.00014 21.6 0.0 0.054 13.2 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF745) AsnA PF03590.15 OWF36720.1 - 0.00015 21.6 9.3 0.22 11.2 0.4 3.7 1 1 3 4 4 4 2 Aspartate-ammonia ligase HSBP1 PF06825.12 OWF36720.1 - 0.00016 21.5 35.9 4.4 7.2 0.9 10.4 4 3 3 8 8 8 0 Heat shock factor binding protein 1 LTXXQ PF07813.12 OWF36720.1 - 0.00017 22.3 1.1 44 4.9 0.0 5.2 1 1 4 6 6 6 0 LTXXQ motif family protein NPV_P10 PF05531.12 OWF36720.1 - 0.00018 21.9 17.7 1.1e+03 0.2 17.7 3.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Med29 PF11568.8 OWF36720.1 - 0.00018 21.7 12.0 3.5 7.8 0.1 4.5 1 1 4 5 5 5 0 Mediator complex subunit 29 Dor1 PF04124.12 OWF36720.1 - 0.00019 20.3 12.6 0.14 10.8 2.0 3.1 1 1 0 2 2 2 2 Dor1-like family Perilipin PF03036.16 OWF36720.1 - 0.00019 20.6 2.1 0.33 9.9 0.1 3.0 1 1 3 4 4 4 2 Perilipin family DUF4795 PF16043.5 OWF36720.1 - 0.0002 21.1 18.0 0.2 11.2 2.6 3.3 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) ATPase_2 PF01637.18 OWF36720.1 - 0.00021 21.3 22.4 0.28 11.1 2.3 4.4 1 1 2 3 3 3 1 ATPase domain predominantly from Archaea DUF3921 PF13060.6 OWF36720.1 - 0.00027 20.9 10.7 3.8 7.6 0.3 4.8 1 1 5 6 6 6 0 Protein of unknown function (DUF3921) TelA PF05816.11 OWF36720.1 - 0.00031 19.9 25.5 0.0042 16.2 10.1 2.7 1 1 2 3 3 3 2 Toxic anion resistance protein (TelA) CLZ PF16526.5 OWF36720.1 - 0.00032 21.0 12.6 3.3 8.2 0.5 4.9 1 1 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BORCS8 PF10167.9 OWF36720.1 - 0.00054 19.9 7.9 0.34 10.9 1.7 3.1 1 1 2 3 3 3 2 BLOC-1-related complex sub-unit 8 PHA_synth_III_E PF09712.10 OWF36720.1 - 0.00064 18.9 0.3 0.56 9.2 0.0 2.0 1 1 1 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DCX PF03607.17 OWF36720.1 - 0.00066 19.7 5.3 7.1 6.8 1.2 5.4 1 1 1 2 2 2 0 Doublecortin PhaP_Bmeg PF09602.10 OWF36720.1 - 0.0007 19.6 14.2 0.0063 16.5 9.1 2.9 1 1 1 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Fib_alpha PF08702.10 OWF36720.1 - 0.00075 19.7 20.3 1 9.5 14.5 3.1 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Sec34 PF04136.15 OWF36720.1 - 0.00076 19.4 16.4 0.65 9.9 4.1 3.3 1 1 2 3 3 3 1 Sec34-like family Prominin PF05478.11 OWF36720.1 - 0.00091 17.3 12.8 0.0019 16.3 12.8 1.5 1 1 0 1 1 1 1 Prominin APG17 PF04108.12 OWF36720.1 - 0.00098 18.3 15.9 0.037 13.1 15.8 2.5 1 1 0 1 1 1 1 Autophagy protein Apg17 IFT20 PF14931.6 OWF36720.1 - 0.001 19.2 4.2 11 6.3 0.1 4.1 1 1 2 4 4 4 0 Intraflagellar transport complex B, subunit 20 DUF3450 PF11932.8 OWF36720.1 - 0.0011 18.3 11.2 0.053 12.8 1.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DHR10 PF18595.1 OWF36720.1 - 0.0011 19.0 7.0 4.6 7.3 0.3 4.2 1 1 4 5 5 5 0 Designed helical repeat protein 10 domain DUF3958 PF13125.6 OWF36720.1 - 0.0012 19.0 5.4 9 6.6 0.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3958) FAP206 PF12018.8 OWF36720.1 - 0.0014 18.3 7.2 0.021 14.4 1.7 2.9 1 1 1 2 2 2 1 Domain of unknown function ATG16 PF08614.11 OWF36720.1 - 0.0016 18.7 3.6 0.034 14.4 0.8 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) FliD_C PF07195.12 OWF36720.1 - 0.0016 17.9 18.8 0.27 10.6 8.8 3.0 1 1 1 2 2 2 2 Flagellar hook-associated protein 2 C-terminus DUF3683 PF12447.8 OWF36720.1 - 0.0017 18.4 10.6 0.79 9.9 0.4 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF3683) H-kinase_dim PF02895.14 OWF36720.1 - 0.0017 18.7 11.6 14 6.2 0.4 5.7 1 1 2 4 4 4 0 Signal transducing histidine kinase, homodimeric domain Prefoldin_2 PF01920.20 OWF36720.1 - 0.0028 17.6 17.5 2.1 8.4 8.4 4.3 1 1 1 2 2 2 0 Prefoldin subunit Serine_rich PF08824.10 OWF36720.1 - 0.0029 17.6 7.0 0.18 11.8 7.0 2.8 1 1 0 1 1 1 1 Serine rich protein interaction domain Prefoldin PF02996.17 OWF36720.1 - 0.0032 17.4 15.5 3.9 7.4 0.8 4.6 1 1 2 4 4 4 0 Prefoldin subunit CREPT PF16566.5 OWF36720.1 - 0.0038 17.4 9.9 0.17 12.0 3.5 2.9 1 1 1 2 2 2 2 Cell-cycle alteration and expression-elevated protein in tumour DUF2535 PF10751.9 OWF36720.1 - 0.0045 17.5 13.6 7.5 7.1 0.4 5.5 1 1 5 6 6 6 0 Protein of unknown function (DUF2535) DUF2203 PF09969.9 OWF36720.1 - 0.0051 17.5 0.9 1.1 10.0 0.9 2.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) SKA1 PF07160.12 OWF36720.1 - 0.0056 16.6 11.7 1.3 8.9 0.8 3.2 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 IKBKB_SDD PF18397.1 OWF36720.1 - 0.0073 15.6 11.1 0.016 14.5 5.6 2.1 1 1 1 2 2 2 2 IQBAL scaffold dimerization domain KAR9 PF08580.10 OWF36720.1 - 0.0084 14.7 14.0 0.11 11.0 6.8 2.1 1 1 1 2 2 2 2 Yeast cortical protein KAR9 KxDL PF10241.9 OWF36720.1 - 0.0086 16.3 18.8 0.41 10.9 2.9 3.8 1 1 2 3 3 3 1 Uncharacterized conserved protein DUF489 PF04356.12 OWF36720.1 - 0.0096 15.9 11.6 0.5 10.3 3.5 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF489) HBM PF16591.5 OWF36720.1 - 0.01 15.3 6.2 0.051 13.0 5.7 2.2 1 1 0 1 1 1 0 Helical bimodular sensor domain IL11 PF07400.11 OWF36720.1 - 0.01 15.5 12.4 1.9 8.1 1.6 4.3 1 1 2 4 4 4 0 Interleukin 11 MscS_porin PF12795.7 OWF36720.1 - 0.01 15.4 10.2 0.06 12.9 6.6 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain ApoO PF09769.9 OWF36720.1 - 0.011 15.7 0.3 28 4.7 0.0 3.6 1 1 3 4 4 4 0 Apolipoprotein O DUF1351 PF07083.11 OWF36720.1 - 0.012 15.4 12.4 0.03 14.1 5.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1351) Rx_N PF18052.1 OWF36720.1 - 0.012 15.8 10.3 4 7.8 0.2 4.2 1 1 2 3 3 3 0 Rx N-terminal domain Cytochrom_B562 PF07361.11 OWF36720.1 - 0.015 15.9 8.6 0.17 12.5 1.5 2.9 1 1 2 3 3 3 0 Cytochrome b562 Fmp27_WPPW PF10359.9 OWF36720.1 - 0.016 14.1 12.3 0.2 10.5 4.0 2.8 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain Ribonuc_red_lgC PF02867.15 OWF36720.1 - 0.018 13.6 1.9 0.52 8.8 0.2 2.0 1 1 1 2 2 2 0 Ribonucleotide reductase, barrel domain SpecificRecomb PF10136.9 OWF36720.1 - 0.02 13.2 1.0 1.1 7.4 0.2 1.8 1 1 1 2 2 2 0 Site-specific recombinase DUF4446 PF14584.6 OWF36720.1 - 0.021 14.8 10.8 2.1 8.3 0.7 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Ribonuc_2-5A PF06479.12 OWF36720.1 - 0.022 14.9 14.2 3 8.1 2.7 3.7 1 1 2 3 3 3 0 Ribonuclease 2-5A Rab5-bind PF09311.11 OWF36720.1 - 0.025 14.0 12.1 0.42 9.9 6.1 2.5 1 1 1 2 2 2 0 Rabaptin-like protein CK2S PF15011.6 OWF36720.1 - 0.026 14.4 10.1 7.8 6.4 2.1 3.8 1 1 2 3 3 3 0 Casein Kinase 2 substrate Spectrin PF00435.21 OWF36720.1 - 0.026 15.0 3.3 0.48 10.9 0.9 2.8 1 1 1 2 2 2 0 Spectrin repeat Exonuc_VII_L PF02601.15 OWF36720.1 - 0.03 13.9 5.7 0.05 13.2 5.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit PhageMin_Tail PF10145.9 OWF36720.1 - 0.03 14.2 17.0 0.74 9.6 2.1 3.7 1 1 1 2 2 2 0 Phage-related minor tail protein P4Ha_N PF08336.11 OWF36720.1 - 0.034 14.2 16.3 2.7 8.0 12.9 3.6 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4298 PF14131.6 OWF36720.1 - 0.036 14.0 16.7 11 6.1 0.7 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4298) AAA_27 PF13514.6 OWF36720.1 - 0.042 13.4 0.1 16 5.0 0.0 3.0 1 1 2 3 3 3 0 AAA domain DUF4881 PF16222.5 OWF36720.1 - 0.047 13.5 0.9 3.5 7.4 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4881) SlyX PF04102.12 OWF36720.1 - 0.047 14.3 12.5 7.4 7.3 0.9 4.0 1 1 4 5 5 5 0 SlyX ATG11 PF10377.9 OWF36720.1 - 0.047 13.8 4.2 45 4.1 0.2 4.0 1 1 5 6 6 6 0 Autophagy-related protein 11 KASH_CCD PF14662.6 OWF36720.1 - 0.05 13.4 12.3 0.19 11.5 7.5 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Talin_middle PF09141.10 OWF36720.1 - 0.079 13.0 3.9 0.67 10.0 1.8 2.9 1 1 1 2 2 2 0 Talin, middle domain Tektin PF03148.14 OWF36720.1 - 0.081 11.7 12.0 1.7 7.3 3.5 2.9 1 1 1 2 2 2 0 Tektin family LXG PF04740.12 OWF36720.1 - 0.094 12.4 20.1 0.24 11.1 20.1 2.0 1 1 0 1 1 1 0 LXG domain of WXG superfamily FPP PF05911.11 OWF36720.1 - 0.098 10.8 13.1 0.76 7.9 3.2 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Occludin_ELL PF07303.13 OWF36720.1 - 0.1 13.4 11.0 13 6.5 0.5 3.4 1 1 2 3 3 3 0 Occludin homology domain CpxA_peri PF16527.5 OWF36720.1 - 0.11 12.9 9.5 1.5 9.2 2.1 3.6 1 1 3 4 4 4 0 Two-component sensor protein CpxA, periplasmic domain DUF2779 PF11074.8 OWF36720.1 - 0.12 12.9 23.3 1.9 9.0 0.9 4.8 1 1 4 5 5 5 0 Domain of unknown function(DUF2779) Toprim PF01751.22 OWF36720.1 - 0.13 12.5 8.9 1.5e+02 2.7 8.9 3.7 1 1 0 1 1 1 0 Toprim domain BLOC1_2 PF10046.9 OWF36720.1 - 0.13 12.6 20.4 1.5 9.2 3.9 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 OWF36720.1 - 0.13 12.7 5.5 8.4 6.8 5.5 2.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Mer2 PF09074.10 OWF36720.1 - 0.15 11.9 18.7 0.35 10.7 18.8 1.7 1 1 0 1 1 1 0 Mer2 Polysacc_deac_1 PF01522.21 OWF36720.1 - 0.16 11.9 1.1 2.1 8.2 0.0 3.0 1 1 1 2 2 2 0 Polysaccharide deacetylase CENP-F_leu_zip PF10473.9 OWF36720.1 - 0.16 12.0 8.9 0.4 10.7 4.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sigma70_ner PF04546.13 OWF36720.1 - 0.16 11.8 4.3 2.5 8.0 0.6 2.3 1 1 1 2 2 2 0 Sigma-70, non-essential region Myosin_tail_1 PF01576.19 OWF36720.1 - 0.17 9.7 7.4 1.8 6.3 2.4 1.7 1 1 0 1 1 1 0 Myosin tail Translin PF01997.16 OWF36720.1 - 0.17 11.9 8.2 72 3.3 8.2 2.6 1 1 0 1 1 1 0 Translin family IDO PF01231.18 OWF36720.1 - 0.18 10.6 7.5 5.1 5.8 0.8 3.4 1 1 2 3 3 3 0 Indoleamine 2,3-dioxygenase zf-CCCH_6 PF18585.1 OWF36720.1 - 0.19 11.6 13.3 1e+02 2.9 0.2 6.6 2 2 6 9 9 9 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF2748 PF10871.8 OWF36720.1 - 0.19 10.3 18.7 1.4 7.5 2.5 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2748) DUF1043 PF06295.12 OWF36720.1 - 0.21 11.6 16.1 4.2 7.4 1.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) Sec8_exocyst PF04048.14 OWF36720.1 - 0.21 11.4 18.9 4.6 7.1 3.8 3.4 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Mce4_CUP1 PF11887.8 OWF36720.1 - 0.24 10.8 6.0 4.3 6.7 0.7 2.2 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative FapA PF03961.13 OWF36720.1 - 0.25 9.9 16.9 0.86 8.1 6.9 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Mod_r PF07200.13 OWF36720.1 - 0.26 11.4 18.2 1.5e+02 2.4 18.2 2.2 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein IFT57 PF10498.9 OWF36720.1 - 0.26 10.2 10.1 0.44 9.5 5.0 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ArsR PF09824.9 OWF36720.1 - 0.27 10.8 13.0 1.3 8.6 1.2 3.2 1 1 2 3 3 3 0 ArsR transcriptional regulator AIP3 PF03915.13 OWF36720.1 - 0.28 10.2 16.0 0.43 9.6 7.2 2.3 1 1 1 2 2 2 0 Actin interacting protein 3 APG6_N PF17675.1 OWF36720.1 - 0.3 11.6 9.5 30 5.1 9.5 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region ArsA_ATPase PF02374.15 OWF36720.1 - 0.34 10.0 5.8 4.4 6.4 2.9 2.3 1 1 2 3 3 3 0 Anion-transporting ATPase Med9 PF07544.13 OWF36720.1 - 0.35 11.0 18.7 8.3 6.6 6.2 3.6 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PI3K_P85_iSH2 PF16454.5 OWF36720.1 - 0.42 10.2 14.5 2.3 7.8 2.7 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_16 PF13191.6 OWF36720.1 - 0.44 10.9 9.8 8.9e+02 0.1 9.8 3.5 1 1 0 1 1 1 0 AAA ATPase domain AI-2E_transport PF01594.16 OWF36720.1 - 0.44 9.7 14.5 1.3e+03 -1.7 14.2 3.0 1 1 0 1 1 0 0 AI-2E family transporter Fes1 PF08609.10 OWF36720.1 - 0.51 11.2 9.6 14 6.6 0.6 4.0 1 1 3 4 4 4 0 Nucleotide exchange factor Fes1 HEPN PF05168.14 OWF36720.1 - 0.61 10.2 7.0 16 5.7 0.5 3.2 1 1 2 3 3 2 0 HEPN domain WEMBL PF05701.11 OWF36720.1 - 0.63 8.7 3.2 0.8 8.3 3.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Seryl_tRNA_N PF02403.22 OWF36720.1 - 0.63 10.3 12.9 5.9 7.2 2.8 3.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain UPF0184 PF03670.13 OWF36720.1 - 0.69 10.3 20.6 1.7 9.1 1.2 4.4 1 1 4 5 5 5 0 Uncharacterised protein family (UPF0184) Coprogen_oxidas PF01218.18 OWF36720.1 - 0.7 8.6 3.5 20 3.7 0.1 3.4 1 1 3 4 4 4 0 Coproporphyrinogen III oxidase DUF643 PF04867.12 OWF36720.1 - 0.81 10.3 22.8 17 6.1 0.6 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF643) FmiP_Thoc5 PF09766.9 OWF36720.1 - 0.99 8.6 17.3 2.3 7.4 3.8 3.3 1 1 2 3 3 3 0 Fms-interacting protein/Thoc5 Cas_Csa4 PF09703.10 OWF36720.1 - 1 8.6 10.4 2.3 7.4 4.8 2.9 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa4) SseC PF04888.12 OWF36720.1 - 1.2 8.6 15.9 7.7 6.0 1.7 3.5 1 1 3 4 4 4 0 Secretion system effector C (SseC) like family DUF5082 PF16888.5 OWF36720.1 - 1.3 9.3 22.6 72 3.7 0.3 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) MtrB PF05440.12 OWF36720.1 - 1.7 9.1 12.6 61 4.1 0.2 4.5 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B EMP24_GP25L PF01105.24 OWF36720.1 - 1.7 8.6 13.5 13 5.7 0.3 4.4 1 1 3 4 4 4 0 emp24/gp25L/p24 family/GOLD EspB PF05802.11 OWF36720.1 - 2 8.4 7.2 31 4.5 1.8 3.1 1 1 2 3 3 3 0 Enterobacterial EspB protein Med2 PF11214.8 OWF36720.1 - 2.1 8.6 23.8 15 5.8 3.0 4.7 1 1 3 4 4 4 0 Mediator complex subunit 2 DUF3247 PF11607.8 OWF36720.1 - 2.3 8.6 5.1 58 4.0 0.1 3.7 1 1 5 6 6 4 0 Protein of unknown function (DUF3247) Pox_Ag35 PF03286.14 OWF36720.1 - 2.3 8.0 7.8 15 5.4 1.2 3.1 1 1 3 4 4 4 0 Pox virus Ag35 surface protein Spc29 PF17082.5 OWF36720.1 - 2.4 7.9 18.9 31 4.3 8.2 2.8 1 1 1 2 2 2 0 Spindle Pole Component 29 Dynein_C PF18199.1 OWF36720.1 - 2.6 7.2 5.2 6.5 5.9 1.8 2.6 1 1 1 2 2 2 0 Dynein heavy chain C-terminal domain Scaffolding_pro PF11418.8 OWF36720.1 - 2.8 8.6 10.1 27 5.4 0.8 3.8 1 1 3 4 4 4 0 Phi29 scaffolding protein CAP_N PF01213.19 OWF36720.1 - 3.4 7.1 5.9 12 5.3 1.5 3.1 1 1 1 3 3 2 0 Adenylate cyclase associated (CAP) N terminal HMMR_N PF15905.5 OWF36720.1 - 4 6.8 15.4 5.2 6.4 3.8 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF16 PF01519.16 OWF36720.1 - 4.7 7.8 11.0 11 6.6 1.3 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 AAA_19 PF13245.6 OWF36720.1 - 5.1 7.4 9.5 2.8e+02 1.8 8.9 2.5 1 1 0 1 1 1 0 AAA domain CENP-Q PF13094.6 OWF36720.1 - 5.5 7.2 14.4 3.1e+03 -1.8 14.5 3.8 1 1 0 1 1 0 0 CENP-Q, a CENPA-CAD centromere complex subunit Hormone_1 PF00103.20 OWF36720.1 - 5.6 6.6 17.3 19 4.9 7.5 2.6 1 1 1 2 2 2 0 Somatotropin hormone family LOH1CR12 PF10158.9 OWF36720.1 - 6.9 6.7 12.9 47 4.0 2.1 3.6 1 1 2 3 3 3 0 Tumour suppressor protein XhlA PF10779.9 OWF36720.1 - 7.2 6.9 19.3 11 6.3 0.5 4.5 1 1 5 6 6 6 0 Haemolysin XhlA L27_N PF09060.10 OWF36720.1 - 8.3 6.6 21.9 41 4.4 0.3 6.4 1 1 7 9 9 9 0 L27_N DUF4988 PF16378.5 OWF36720.1 - 9.5 5.8 12.6 9.7 5.8 0.7 3.6 1 1 3 4 4 4 0 Domain of unknown function Aldo_ket_red PF00248.21 OWF36722.1 - 2.1e-79 266.8 0.0 2.4e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FKBP_C PF00254.28 OWF36723.1 - 2.2e-35 120.8 0.0 2.9e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_5 PF13202.6 OWF36723.1 - 0.0081 15.6 0.3 0.016 14.7 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OWF36723.1 - 0.012 15.5 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 OWF36723.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 OWF36723.1 - 0.059 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 OWF36723.1 - 0.098 13.1 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF3045 PF11243.8 OWF36724.1 - 0.00074 19.6 17.6 9.2 6.5 0.8 6.5 1 1 5 6 6 6 6 Protein of unknown function (DUF3045) ABC_export PF16962.5 OWF36724.1 - 0.0046 15.5 24.2 3.4 6.0 0.3 6.4 2 1 7 9 9 9 8 Putative ABC exporter DUF1836 PF08876.11 OWF36724.1 - 0.0066 16.5 2.7 16 5.6 0.1 3.9 1 1 3 4 4 4 2 Domain of unknown function (DUF1836) Plasmodium_HRP PF05403.11 OWF36724.1 - 0.014 15.2 9.4 0.19 11.5 9.4 2.1 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) YonK PF09642.10 OWF36724.1 - 3.5 7.9 10.2 86 3.4 0.3 5.3 1 1 5 6 6 6 0 YonK protein TonB_N PF16031.5 OWF36725.1 - 0.038 14.5 0.2 0.038 14.5 0.2 1.7 2 0 0 2 2 2 0 TonB polyproline region FtsK_SpoIIIE PF01580.18 OWF36725.1 - 0.17 11.3 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Flavokinase PF01687.17 OWF36726.1 - 3.7e-34 117.4 0.0 4.4e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase DUF1258 PF06869.12 OWF36726.1 - 0.0018 17.8 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) COR PF16095.5 OWF36727.1 - 7.7e-11 42.2 0.3 1.9e-10 40.9 0.3 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF36727.1 - 4.8e-08 33.2 0.3 0.00034 20.8 0.0 3.2 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF36727.1 - 5e-06 26.6 0.0 0.0003 20.9 0.0 2.7 2 0 0 2 2 2 1 Death domain Arf PF00025.21 OWF36727.1 - 0.001 18.5 0.1 0.005 16.3 0.0 2.2 3 0 0 3 3 3 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OWF36727.1 - 0.034 13.9 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OWF36727.1 - 0.14 12.4 0.0 0.71 10.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain AWS PF17907.1 OWF36728.1 - 0.13 12.3 0.2 0.13 12.3 0.2 6.2 2 1 3 5 5 5 0 AWS domain Keratin_B2_2 PF13885.6 OWF36729.1 - 0.026 14.5 26.9 0.46 10.5 5.1 3.2 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 OWF36729.1 - 1.1 9.2 33.5 11 6.0 33.5 2.0 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Keratin_B2_2 PF13885.6 OWF36730.1 - 0.029 14.3 10.1 0.066 13.2 7.3 2.1 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein Keratin_B2_2 PF13885.6 OWF36731.1 - 9.7 6.2 12.0 63 3.6 12.0 2.1 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Keratin_B2_2 PF13885.6 OWF36732.1 - 0.041 13.8 60.5 1.9 8.5 2.4 6.7 3 1 1 4 4 4 0 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 OWF36732.1 - 0.26 11.3 74.4 0.78 9.7 15.2 3.7 1 1 3 4 4 4 0 Keratin, high sulfur B2 protein PAC4 PF16093.5 OWF36736.1 - 0.0048 17.1 1.4 4.5 7.5 0.0 3.0 3 0 0 3 3 3 2 Proteasome assembly chaperone 4 DUF5114 PF17141.4 OWF36736.1 - 2.9 8.5 6.9 18 6.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5114) Alpha-amylase_C PF02806.18 OWF36738.1 - 0.049 14.1 0.3 3 8.4 0.0 2.7 1 1 1 2 2 2 0 Alpha amylase, C-terminal all-beta domain Vert_IL3-reg_TF PF06529.11 OWF36738.1 - 0.13 11.4 0.4 15 4.6 0.2 2.2 2 0 0 2 2 2 0 Vertebrate interleukin-3 regulated transcription factor DUF4642 PF15484.6 OWF36738.1 - 0.35 11.1 2.4 0.36 11.1 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) Mab-21 PF03281.14 OWF36739.1 - 2.5e-26 92.7 3.6 3.8e-26 92.1 3.6 1.2 1 0 0 1 1 1 1 Mab-21 protein Transposase_22 PF02994.14 OWF36741.1 - 0.037 14.2 1.6 0.13 12.4 0.5 2.4 2 1 0 2 2 2 0 L1 transposable element RBD-like domain DUF5316 PF17247.2 OWF36742.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Pentapeptide_3 PF13576.6 OWF36743.1 - 1.4e-20 73.2 1.7 0.12 12.6 0.2 10.9 2 2 7 9 9 9 5 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 OWF36743.1 - 7.5e-08 32.4 32.4 0.099 12.8 2.7 6.5 1 1 7 9 9 9 8 Pentapeptide repeats (9 copies) Osw5 PF17062.5 OWF36743.1 - 1.4e-06 28.3 38.7 10 6.3 0.2 13.9 1 1 15 17 17 17 3 Outer spore wall 5 Pentapeptide PF00805.22 OWF36743.1 - 1.2 8.8 85.0 3.1 7.6 1.5 12.2 3 1 12 17 17 17 0 Pentapeptide repeats (8 copies) DUF2345 PF10106.9 OWF36744.1 - 0.0055 16.6 0.0 8.2 6.3 0.0 4.6 3 1 3 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF4573 PF15140.6 OWF36744.1 - 0.054 13.3 0.0 5.6 6.7 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4573) TAP35_44 PF07265.11 OWF36744.1 - 0.083 12.9 3.3 27 4.8 0.0 4.1 3 1 1 4 4 4 0 Tapetum specific protein TAP35/TAP44 CUB_2 PF02408.20 OWF36744.1 - 0.29 10.9 12.5 6.7 6.5 0.0 5.4 3 3 4 8 8 8 0 CUB-like domain Rotavirus_VP7 PF05868.11 OWF36744.1 - 4.7 6.5 56.4 1.9 7.8 1.2 8.0 1 1 7 8 8 8 0 Rotavirus major outer capsid protein VP7 DUF4786 PF16027.5 OWF36744.1 - 5.4 7.6 6.7 25 5.4 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4786) DUF3600 PF12207.8 OWF36745.1 - 0.00046 20.1 18.1 4.3 7.3 0.1 8.2 1 1 6 7 7 7 2 Domain of unknown function (DUF3600) DUF2028 PF09667.10 OWF36745.1 - 0.065 13.2 26.0 5.7 6.8 2.6 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF2028) DctA-YdbH PF11739.8 OWF36745.1 - 1.9 8.2 46.8 20 4.8 1.7 11.5 1 1 11 14 14 14 0 Dicarboxylate transport LRR_8 PF13855.6 OWF36746.1 - 0.00077 19.2 5.9 0.0013 18.5 3.5 2.4 1 1 1 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OWF36746.1 - 0.0045 17.4 0.8 0.0045 17.4 0.8 3.0 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF36746.1 - 0.045 14.3 5.5 1.1 10.1 0.0 3.6 3 1 0 3 3 3 0 Leucine Rich Repeat DUF724 PF05266.14 OWF36748.1 - 0.17 11.7 3.3 0.11 12.2 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 OWF36748.1 - 0.34 11.3 2.9 0.54 10.7 1.4 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DED PF01335.21 OWF36749.1 - 1.6e-10 41.1 0.2 1.6e-10 41.1 0.2 2.9 2 1 0 2 2 2 1 Death effector domain Nucleic_acid_bd PF13820.6 OWF36749.1 - 7.3e-05 22.6 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Putative nucleic acid-binding region IDO PF01231.18 OWF36750.1 - 2.6e-77 260.4 0.0 1.2e-76 258.3 0.0 1.8 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cauli_AT PF03233.13 OWF36750.1 - 0.0048 16.8 0.1 0.016 15.2 0.1 1.8 2 0 0 2 2 2 1 Aphid transmission protein TMEM40 PF15817.5 OWF36751.1 - 0.013 15.3 6.6 0.052 13.3 0.3 2.6 2 0 0 2 2 2 0 Transmembrane protein 40 family IFN-gamma PF00714.17 OWF36751.1 - 0.019 14.8 0.0 0.073 12.9 0.0 2.0 1 0 0 1 1 1 0 Interferon gamma VWD PF00094.25 OWF36752.1 - 3.8e-05 24.0 4.3 0.0012 19.1 0.1 4.2 4 1 0 4 4 4 1 von Willebrand factor type D domain C8 PF08742.11 OWF36752.1 - 0.41 11.1 7.7 0.99 9.9 7.7 1.7 1 0 0 1 1 1 0 C8 domain DUF3528 PF12045.8 OWF36753.1 - 1.8 9.2 6.8 9.1 6.9 0.2 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3528) UPF0552 PF10574.9 OWF36753.1 - 7.2 5.9 7.8 2.2 7.5 0.5 2.7 1 1 2 3 3 3 0 Arp2/3-interacting proteins Arpin PBP_dimer PF03717.15 OWF36754.1 - 0.048 14.0 1.2 49 4.2 0.0 3.7 3 1 1 4 4 4 0 Penicillin-binding Protein dimerisation domain DUF3432 PF11914.8 OWF36755.1 - 1.9e-05 24.8 0.0 0.82 9.9 0.0 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF3432) CgtA PF06306.11 OWF36755.1 - 0.57 9.6 10.0 19 4.5 0.4 4.1 1 1 1 3 3 3 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) FMO-like PF00743.19 OWF36756.1 - 3.1e-68 230.5 0.3 6.8e-52 176.6 0.1 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF36756.1 - 1.3e-17 64.0 0.1 1.7e-14 53.8 0.1 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF36756.1 - 1e-14 54.5 0.0 2.8e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF36756.1 - 1.5e-08 34.2 0.1 3.4e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OWF36756.1 - 1.7e-07 31.7 0.2 0.00021 21.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF36756.1 - 7.7e-07 29.0 0.0 0.024 14.2 0.1 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OWF36756.1 - 3.2e-06 27.2 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF36756.1 - 0.00027 21.1 0.1 0.0014 18.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DUF2375 PF09558.10 OWF36756.1 - 0.031 14.3 0.0 5.3 7.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2375) DUF1188 PF06690.11 OWF36756.1 - 0.13 11.8 0.1 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 OWF36756.1 - 0.16 11.2 0.0 0.95 8.7 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SAM_PNT PF02198.16 OWF36756.1 - 0.18 11.8 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain zf-RING_UBOX PF13445.6 OWF36757.1 - 2.7e-11 43.3 6.8 4.8e-11 42.5 4.4 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF36757.1 - 4.3e-09 36.1 8.2 4.3e-09 36.1 8.2 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF36757.1 - 4.4e-08 33.1 4.8 4.4e-08 33.1 4.8 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF36757.1 - 3.1e-07 30.6 7.8 3.1e-07 30.6 7.8 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF36757.1 - 1.5e-06 28.0 8.1 1.5e-06 28.0 8.1 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF36757.1 - 1.6e-06 27.8 9.3 1.6e-06 27.8 9.3 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF36757.1 - 2.4e-06 27.3 7.0 2.4e-06 27.3 7.0 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF36757.1 - 3.4e-05 23.9 5.1 3.4e-05 23.9 5.1 3.2 3 0 0 3 3 3 1 B-box zinc finger EzrA PF06160.12 OWF36757.1 - 0.00096 17.4 17.5 0.00096 17.4 17.5 1.6 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Prok-RING_4 PF14447.6 OWF36757.1 - 0.0048 16.7 6.5 0.0048 16.7 6.5 2.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 U-box PF04564.15 OWF36757.1 - 0.034 14.3 1.2 0.33 11.2 0.0 3.3 4 0 0 4 4 4 0 U-box domain zf-Nse PF11789.8 OWF36757.1 - 0.036 13.9 6.2 0.12 12.2 6.2 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit A_thal_3526 PF09713.10 OWF36757.1 - 0.065 13.5 0.2 0.25 11.6 0.2 2.1 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) zf-rbx1 PF12678.7 OWF36757.1 - 0.14 12.4 4.8 1.1 9.6 4.8 2.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain FapA PF03961.13 OWF36757.1 - 0.32 9.5 13.9 0.7 8.4 13.9 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A ArfGap PF01412.18 OWF36757.1 - 0.82 9.8 9.8 0.6 10.2 5.5 2.8 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Ig_3 PF13927.6 OWF36758.1 - 1e-07 32.5 0.0 9.5e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF36758.1 - 7.3e-06 26.0 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF36758.1 - 1.9e-05 24.9 0.1 0.00012 22.3 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 OWF36758.1 - 0.00021 21.4 0.3 0.013 15.7 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 OWF36758.1 - 0.0029 17.7 0.0 0.0074 16.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Trypsin_2 PF13365.6 OWF36758.1 - 0.01 16.7 0.1 0.034 15.1 0.1 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Ank_2 PF12796.7 OWF36758.1 - 0.064 13.9 0.0 0.41 11.3 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Glyco_transf_10 PF00852.19 OWF36759.1 - 6.4e-44 149.8 1.4 9.9e-44 149.1 1.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF36759.1 - 4.3e-21 75.5 1.3 9.3e-21 74.4 0.2 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Peptidase_M13_N PF05649.13 OWF36762.1 - 3.6e-09 36.8 0.2 4.1e-09 36.6 0.2 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF36763.1 - 1.1e-43 149.2 0.1 1.6e-43 148.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Myb_DNA-bind_4 PF13837.6 OWF36764.1 - 1.3e-07 31.9 2.4 2.1e-07 31.2 2.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OWF36764.1 - 8.7e-06 26.6 0.9 1.6e-05 25.8 0.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Acetyltransf_1 PF00583.25 OWF36765.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Anemone_cytotox PF06369.12 OWF36767.1 - 1.5e-07 31.2 0.1 1.9e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Sea anemone cytotoxic protein Aegerolysin PF06355.13 OWF36767.1 - 0.14 12.2 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Aegerolysin 7TM_GPCR_Srh PF10318.9 OWF36768.1 - 0.18 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh SNF PF00209.18 OWF36769.1 - 2.7e-197 656.6 39.5 3.4e-197 656.3 39.5 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family VWD PF00094.25 OWF36770.1 - 2.7e-19 70.0 1.5 2.7e-19 70.0 1.5 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain CHASE5 PF17149.4 OWF36770.1 - 0.019 14.9 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins BHD_2 PF10404.9 OWF36771.1 - 0.31 12.0 20.1 77 4.4 0.1 6.0 6 0 0 6 6 6 0 Rad4 beta-hairpin domain 2 Cuticle_3 PF11018.8 OWF36771.1 - 0.38 10.9 17.1 0.59 10.3 5.0 2.0 1 1 1 2 2 2 0 Pupal cuticle protein C1 Drf_FH1 PF06346.12 OWF36771.1 - 2.2 8.0 12.0 4.7 6.9 12.0 1.5 1 1 0 1 1 1 0 Formin Homology Region 1 Ion_trans PF00520.31 OWF36772.1 - 3.7e-05 23.1 1.3 0.00013 21.3 1.0 1.8 2 0 0 2 2 2 1 Ion transport protein VAPB_antitox PF02697.14 OWF36772.1 - 0.017 15.9 1.5 0.076 13.8 1.1 2.2 2 1 0 2 2 2 0 Putative antitoxin Uds1 PF15456.6 OWF36772.1 - 0.068 13.3 1.2 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Up-regulated During Septation Type2_restr_D3 PF16902.5 OWF36772.1 - 0.33 10.9 3.3 0.3 11.0 0.9 2.1 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Ski_Sno PF02437.17 OWF36773.1 - 3.7e-06 26.6 1.9 0.91 9.3 0.1 4.3 1 1 3 4 4 4 3 SKI/SNO/DAC family Herpes_UL49_2 PF04823.12 OWF36773.1 - 0.066 13.3 12.7 5.7 7.1 0.1 5.5 2 2 4 6 6 6 0 Herpesvirus UL49 tegument protein Collagen_mid PF15984.5 OWF36774.1 - 0.015 15.1 0.3 0.066 13.0 0.2 1.9 1 1 1 2 2 2 0 Bacterial collagen, middle region Vma12 PF11712.8 OWF36777.1 - 0.2 11.7 4.0 0.8 9.8 4.0 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase OCD_Mu_crystall PF02423.15 OWF36778.1 - 0.1 11.5 0.2 0.12 11.3 0.2 1.0 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Mur_ligase PF01225.25 OWF36779.1 - 0.13 12.6 0.0 65 3.9 0.0 4.1 4 1 1 5 5 5 0 Mur ligase family, catalytic domain Neur_chan_LBD PF02931.23 OWF36780.1 - 0.00039 19.9 0.2 0.00048 19.6 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain SGL PF08450.12 OWF36781.1 - 0.00023 20.8 0.1 0.00026 20.7 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OWF36781.1 - 0.00026 20.9 0.2 0.00064 19.7 0.0 1.8 2 0 0 2 2 2 1 Beta-propeller repeat NHL PF01436.21 OWF36781.1 - 0.0011 18.9 0.3 2 8.6 0.1 2.5 2 1 0 2 2 2 2 NHL repeat SdiA-regulated PF06977.11 OWF36781.1 - 0.018 14.3 0.0 0.65 9.2 0.0 2.0 1 1 1 2 2 2 0 SdiA-regulated zf-RING_UBOX PF13445.6 OWF36782.1 - 3.6e-11 42.9 4.3 3.6e-11 42.9 4.3 2.7 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF36782.1 - 3.7e-08 33.1 8.0 3.7e-08 33.1 8.0 3.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF36782.1 - 6.8e-08 32.5 10.0 6.8e-08 32.5 10.0 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF36782.1 - 1.1e-07 32.1 7.4 1.1e-07 32.1 7.4 3.6 3 1 0 3 3 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF36782.1 - 8.9e-07 28.8 6.1 8.9e-07 28.8 6.1 3.4 3 1 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF36782.1 - 1.8e-06 27.7 10.1 1.8e-06 27.7 10.1 4.3 4 2 2 6 6 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF36782.1 - 6e-05 22.8 7.3 6e-05 22.8 7.3 3.9 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SbsC_C PF18058.1 OWF36782.1 - 0.0013 19.0 1.8 0.68 10.2 0.1 2.2 1 1 1 2 2 2 2 SbsC C-terminal domain zf-B_box PF00643.24 OWF36782.1 - 0.0033 17.5 9.8 0.0033 17.5 9.8 4.3 4 1 0 4 4 3 2 B-box zinc finger Baculo_PEP_C PF04513.12 OWF36782.1 - 0.018 15.1 5.6 0.019 15.0 2.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NHL PF01436.21 OWF36782.1 - 0.027 14.5 0.1 6.3 7.0 0.1 3.1 2 0 0 2 2 2 0 NHL repeat Apolipoprotein PF01442.18 OWF36782.1 - 0.032 14.1 4.8 0.097 12.5 4.5 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 OWF36782.1 - 0.086 12.6 6.2 0.16 11.7 6.2 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Mit_KHE1 PF10173.9 OWF36782.1 - 0.12 12.4 1.1 0.21 11.7 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related AAA_15 PF13175.6 OWF36782.1 - 0.18 11.5 5.8 0.26 10.9 5.8 1.2 1 0 0 1 1 1 0 AAA ATPase domain ApoLp-III PF07464.11 OWF36782.1 - 0.22 11.6 6.0 0.41 10.7 6.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF945 PF06097.11 OWF36782.1 - 2.4 7.2 6.8 3.5 6.6 6.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) DUF4359 PF14271.6 OWF36782.1 - 3.5 8.4 7.8 5.6 7.8 0.3 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) Bacteriocin_IIc PF10439.9 OWF36783.1 - 0.009 16.1 157.6 1.4 9.1 19.0 7.5 1 1 4 5 5 5 4 Bacteriocin class II with double-glycine leader peptide Bacteriocin_IIc PF10439.9 OWF36784.1 - 2.1 8.5 147.1 1.8e+04 -109.6 147.1 7.1 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Bacteriocin_IIc PF10439.9 OWF36785.1 - 2.2 8.5 189.9 9.1 6.5 19.1 8.3 1 1 3 4 4 4 0 Bacteriocin class II with double-glycine leader peptide SHIPPO-rpt PF07004.12 OWF36786.1 - 1.5e-09 38.3 37.3 0.00012 22.9 2.1 6.3 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat TMEM154 PF15102.6 OWF36788.1 - 0.0022 17.9 8.5 0.0022 17.9 8.5 2.5 2 1 0 2 2 2 1 TMEM154 protein family Trehalase PF01204.18 OWF36789.1 - 5e-68 230.2 5.3 2.3e-60 204.9 2.5 2.0 2 0 0 2 2 2 2 Trehalase Bac_rhamnosid6H PF17389.2 OWF36789.1 - 0.00093 18.5 0.4 0.1 11.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_63 PF03200.16 OWF36789.1 - 0.0012 17.7 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Izumo-Ig PF16706.5 OWF36790.1 - 0.00032 20.7 0.5 0.6 10.2 0.0 2.7 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain ig PF00047.25 OWF36790.1 - 0.0011 19.0 24.3 0.043 14.0 1.1 5.3 3 2 0 3 3 3 1 Immunoglobulin domain PG_binding_1 PF01471.18 OWF36790.1 - 0.0042 17.3 0.1 3.5 7.9 0.0 2.8 3 0 0 3 3 3 2 Putative peptidoglycan binding domain Ig_3 PF13927.6 OWF36790.1 - 0.026 15.1 28.4 4.7 7.9 4.0 5.5 4 2 0 4 4 4 0 Immunoglobulin domain YbbR PF07949.12 OWF36790.1 - 0.036 14.4 6.0 2.2 8.7 1.1 2.7 2 0 0 2 2 2 0 YbbR-like protein Sushi PF00084.20 OWF36790.1 - 0.13 12.9 3.7 13 6.5 0.1 3.9 5 0 0 5 5 5 0 Sushi repeat (SCR repeat) DMP12 PF16779.5 OWF36790.1 - 0.3 11.1 1.2 16 5.5 0.0 2.8 2 0 0 2 2 2 0 DNA-mimic protein DUF4189 PF13827.6 OWF36790.1 - 1.3 9.6 9.3 7.8 7.1 0.4 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4189) DUF4983 PF16356.5 OWF36790.1 - 2 9.3 5.1 1.5 9.6 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4983) C2-set_2 PF08205.12 OWF36790.1 - 5.8 7.1 7.5 13 6.0 0.3 4.1 3 2 0 3 3 3 0 CD80-like C2-set immunoglobulin domain rve PF00665.26 OWF36791.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 OWF36791.1 - 0.14 12.5 0.1 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Transposase Galactosyl_T PF01762.21 OWF36794.1 - 9.4e-43 146.3 0.1 1.2e-42 146.0 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF36794.1 - 0.00035 20.1 0.0 0.00051 19.6 0.0 1.3 1 1 0 1 1 1 1 Fringe-like NB-LRR PF12061.8 OWF36796.1 - 0.09 12.1 3.1 6.5 6.0 0.2 2.9 1 1 2 3 3 3 0 Late blight resistance protein R1 dCache_1 PF02743.18 OWF36797.1 - 0.0024 17.7 0.4 0.0036 17.1 0.4 1.3 1 0 0 1 1 1 1 Cache domain HTH_10 PF04967.12 OWF36797.1 - 0.089 12.6 0.2 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain GspH PF12019.8 OWF36798.1 - 5.2e-07 30.1 28.3 31 5.0 10.4 6.1 1 1 1 2 2 2 0 Type II transport protein GspH MliC PF09864.9 OWF36798.1 - 5.1e-06 26.3 11.9 1.6 8.7 0.3 6.4 1 1 4 5 5 5 3 Membrane-bound lysozyme-inhibitor of c-type lysozyme CBM39 PF15886.5 OWF36798.1 - 8.4e-06 25.6 0.3 13 5.8 0.0 6.6 1 1 4 7 7 7 1 Carbohydrate binding domain (family 32) PCC_BT PF18140.1 OWF36798.1 - 9.7e-06 25.9 0.3 1.3 9.4 0.0 3.3 1 1 3 4 4 4 4 Propionyl-coenzyme A carboxylase BT domain DUF4999 PF16390.5 OWF36798.1 - 1.2e-05 25.4 0.1 30 4.9 0.0 7.5 1 1 8 9 9 9 0 Domain of unknown function Pab87_oct PF13969.6 OWF36798.1 - 6.5e-05 22.9 0.0 53 4.0 0.0 5.9 1 1 4 7 7 7 0 Pab87 octamerisation domain Plk4_PB1 PF18190.1 OWF36798.1 - 0.00031 20.9 3.2 21 5.3 0.0 5.6 1 1 3 6 6 6 0 Polo-like Kinase 4 Polo Box 1 DUF2240 PF09999.9 OWF36798.1 - 0.00057 19.6 0.7 11 5.7 0.0 5.6 1 1 5 6 6 6 1 Uncharacterized protein conserved in archaea (DUF2240) SRP9-21 PF05486.12 OWF36798.1 - 0.0037 17.6 60.0 7.7 7.0 0.1 12.8 1 1 5 6 6 4 1 Signal recognition particle 9 kDa protein (SRP9) HPTransfase PF10090.9 OWF36798.1 - 0.027 14.3 0.1 38 4.1 0.0 4.4 1 1 4 5 5 5 0 Histidine phosphotransferase C-terminal domain DotD PF16816.5 OWF36798.1 - 0.13 12.2 0.2 2e+02 2.0 0.0 5.1 7 0 0 7 7 7 0 DotD protein CsgF PF10614.9 OWF36798.1 - 0.25 11.6 14.0 27 5.0 0.2 5.3 1 1 4 6 6 6 0 Type VIII secretion system (T8SS), CsgF protein SFTA2 PF15210.6 OWF36798.1 - 1.5 8.8 37.8 5.6 7.0 0.5 10.5 4 4 7 11 11 11 0 Surfactant-associated protein 2 Cadherin-like PF12733.7 OWF36798.1 - 1.9 9.0 35.6 4.2e+02 1.6 9.5 6.3 1 1 1 2 2 1 0 Cadherin-like beta sandwich domain TFR_dimer PF04253.15 OWF36799.1 - 3.9e-29 101.2 0.1 8.6e-29 100.1 0.0 1.5 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain 7tm_1 PF00001.21 OWF36800.1 - 1.5e-22 80.2 4.4 2.3e-22 79.6 4.4 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF36800.1 - 0.0001 21.8 6.4 0.0001 21.8 6.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF36801.1 - 3e-47 161.2 20.2 4.1e-47 160.7 20.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF36801.1 - 7.1e-17 61.6 24.9 9.3e-17 61.3 24.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF36801.1 - 3.1e-05 23.8 21.1 5.3e-05 23.1 21.1 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF36801.1 - 0.00015 21.5 24.6 0.00015 21.5 24.6 2.3 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4064 PF13273.6 OWF36801.1 - 0.41 11.0 6.2 0.51 10.6 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) His_Phos_2 PF00328.22 OWF36802.1 - 1.5e-05 24.6 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Xan_ur_permease PF00860.20 OWF36803.1 - 5.5e-18 64.8 7.8 5.5e-18 64.8 7.8 1.3 2 0 0 2 2 2 1 Permease family DUF1700 PF08006.11 OWF36803.1 - 1.3 8.5 3.7 1.8 8.1 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) RasGEF_N PF00618.20 OWF36805.1 - 7.2 6.9 10.0 3.1 8.1 2.4 2.6 1 1 1 2 2 2 0 RasGEF N-terminal motif Shisa PF13908.6 OWF36806.1 - 0.0001 22.6 0.9 0.00021 21.6 0.4 1.7 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 OWF36806.1 - 0.00026 20.9 0.2 0.0009 19.2 0.0 2.0 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 TMEM154 PF15102.6 OWF36806.1 - 0.0018 18.2 1.4 0.0043 17.0 1.4 1.7 1 0 0 1 1 1 1 TMEM154 protein family Cytomega_TRL10 PF06084.11 OWF36806.1 - 0.0078 16.2 1.6 0.026 14.5 1.6 1.9 1 1 0 1 1 1 1 Cytomegalovirus TRL10 protein DUF5305 PF17231.2 OWF36806.1 - 0.0093 15.4 0.4 0.013 14.9 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) RIFIN PF02009.16 OWF36806.1 - 0.019 14.9 1.5 0.019 14.9 1.5 1.6 2 0 0 2 2 2 0 Rifin SRTM1 PF15872.5 OWF36806.1 - 0.038 14.2 1.4 0.2 11.9 0.3 2.4 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 ECSCR PF15820.5 OWF36806.1 - 0.063 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 OWF36806.1 - 0.077 13.9 0.2 0.26 12.2 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 OWF36806.1 - 0.15 11.6 0.6 0.38 10.4 0.6 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Orf78 PF06024.12 OWF36806.1 - 0.57 10.5 2.9 1.2 9.5 1.2 2.3 1 1 1 2 2 2 0 Orf78 (ac78) DUF4834 PF16118.5 OWF36806.1 - 9.1 7.3 9.8 2 9.4 4.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) zf-B_box PF00643.24 OWF36807.1 - 3e-05 24.1 2.5 5.6e-05 23.2 2.5 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 OWF36807.1 - 0.016 15.4 2.3 0.035 14.3 2.3 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) BBS2_Mid PF14783.6 OWF36807.1 - 0.04 13.9 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Cornifin PF02389.15 OWF36808.1 - 2.3e-07 31.1 6.7 1.2e-05 25.6 4.8 2.1 1 1 1 2 2 2 2 Cornifin (SPRR) family Fibrinogen_BP PF08017.11 OWF36808.1 - 0.00013 20.5 0.0 0.00015 20.3 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein CHU_C PF13585.6 OWF36808.1 - 0.046 13.8 1.3 16 5.7 0.4 3.6 1 1 1 2 2 2 0 C-terminal domain of CHU protein family TaqI_C PF12950.7 OWF36808.1 - 0.096 12.8 2.5 17 5.5 2.5 3.1 1 1 0 1 1 1 0 TaqI-like C-terminal specificity domain Cu-oxidase_3 PF07732.15 OWF36810.1 - 7.6e-40 135.6 3.2 1.3e-35 122.0 0.6 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF36810.1 - 7.8e-35 119.6 8.4 3e-31 108.0 0.4 3.4 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF36810.1 - 2.6e-25 89.4 0.8 8.3e-23 81.3 0.8 2.9 2 1 0 2 2 2 2 Multicopper oxidase SKG6 PF08693.10 OWF36810.1 - 6 6.4 7.1 13 5.3 7.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain N6-adenineMlase PF10237.9 OWF36813.1 - 0.051 13.4 9.8 10 5.9 0.1 4.1 1 1 2 4 4 4 0 Probable N6-adenine methyltransferase RRM PF10378.9 OWF36813.1 - 0.59 9.9 6.4 20 5.0 0.0 4.1 4 0 0 4 4 4 0 Putative RRM domain Cornifin PF02389.15 OWF36814.1 - 0.012 15.8 0.3 0.027 14.7 0.3 1.6 1 1 0 1 1 1 0 Cornifin (SPRR) family Forkhead_N PF08430.12 OWF36814.1 - 7 7.3 25.0 12 6.5 11.8 2.6 1 1 1 2 2 2 0 Forkhead N-terminal region Cornifin PF02389.15 OWF36815.1 - 2.7e-09 37.3 2.8 2.1e-05 24.7 0.1 2.4 1 1 0 2 2 2 2 Cornifin (SPRR) family Forkhead_N PF08430.12 OWF36816.1 - 0.15 12.7 15.2 0.23 12.1 15.2 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region DUF3432 PF11914.8 OWF36816.1 - 6.5 7.1 17.9 1.9e+02 2.4 17.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) NUDE_C PF04880.13 OWF36816.1 - 8 6.9 7.7 12 6.3 7.7 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Tox-ART-HYD1 PF15633.6 OWF36817.1 - 0.037 14.7 0.0 0.053 14.2 0.0 1.3 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase DUF2341 PF10102.9 OWF36817.1 - 0.088 13.4 0.0 0.14 12.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2341) Tox-ART-HYD1 PF15633.6 OWF36818.1 - 9.5e-07 29.4 0.2 2e-06 28.4 0.2 1.7 1 1 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase PARP PF00644.20 OWF36818.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Sec62 PF03839.16 OWF36818.1 - 2.4 7.6 5.5 2.9 7.4 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 rve PF00665.26 OWF36819.1 - 0.0006 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 OWF36819.1 - 0.081 13.1 1.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 HTH-like domain HELP PF03451.14 OWF36821.1 - 7.1e-06 25.8 50.9 50 3.8 0.2 19.1 3 2 20 23 23 23 19 HELP motif DUF4755 PF15947.5 OWF36822.1 - 0.0035 17.3 3.7 0.13 12.3 0.0 4.2 3 1 3 6 6 6 1 Domain of unknown function (DUF4755) DUF2929 PF11151.8 OWF36822.1 - 0.14 12.4 9.0 21 5.5 0.1 5.7 1 1 6 7 7 7 0 Protein of unknown function (DUF2929) Baculo_8kDa PF06096.11 OWF36822.1 - 0.23 11.6 33.5 0.39 10.8 1.4 9.6 4 4 6 11 11 11 0 Baculoviridae 8.2 KDa protein PAP2_C PF14360.6 OWF36822.1 - 2.6 8.7 5.5 37 5.0 1.4 2.8 2 0 0 2 2 2 0 PAP2 superfamily C-terminal VARLMGL PF14383.6 OWF36823.1 - 0.12 11.9 6.4 1.9e+02 1.7 0.1 6.1 7 0 0 7 7 7 0 DUF761-associated sequence motif F-actin_cap_A PF01267.17 OWF36823.1 - 0.14 11.5 0.2 4.8 6.5 0.0 2.2 1 1 1 2 2 2 0 F-actin capping protein alpha subunit GST_N_3 PF13417.6 OWF36830.1 - 3.4e-12 46.6 0.0 8.1e-12 45.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF36830.1 - 4e-11 43.1 0.0 7.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF36830.1 - 7.3e-05 22.7 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF36830.1 - 0.00022 21.5 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF36830.1 - 0.00023 21.3 0.0 0.00052 20.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF36830.1 - 0.0033 17.6 0.0 0.0073 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF36830.1 - 0.011 16.4 0.0 0.025 15.3 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 OWF36830.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Big_1 PF02369.16 OWF36832.1 - 0.12 12.4 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Big_1 PF02369.16 OWF36835.1 - 0.12 12.4 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) COR PF16095.5 OWF36836.1 - 7.5e-11 42.2 0.2 2.5e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Death PF00531.22 OWF36836.1 - 7.5e-06 26.0 0.0 0.059 13.5 0.0 2.7 2 0 0 2 2 2 2 Death domain Pentapeptide_4 PF13599.6 OWF36837.1 - 8.2e-10 38.7 0.0 0.0052 16.9 0.0 2.5 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) VHP PF02209.19 OWF36837.1 - 0.0011 19.0 16.8 57 3.9 0.1 9.7 2 2 6 10 10 10 1 Villin headpiece domain RE_HindIII PF09518.10 OWF36837.1 - 8 5.6 5.4 1.4e+02 1.5 0.0 3.7 1 1 4 5 5 5 0 HindIII restriction endonuclease zf-C2H2 PF00096.26 OWF36838.1 - 4.9e-23 80.2 31.5 9.6e-07 28.9 1.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF36838.1 - 7.7e-19 67.2 32.8 1.7e-08 34.5 2.0 5.0 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF36838.1 - 2e-14 53.0 37.7 0.00022 21.8 0.8 5.4 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF36838.1 - 2.1e-11 43.5 25.5 0.00081 19.3 2.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF36838.1 - 2.2e-08 34.2 15.2 0.0034 17.6 0.0 4.9 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 OWF36838.1 - 3.2e-06 26.6 10.1 0.38 10.4 0.1 4.4 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 OWF36838.1 - 0.00015 21.7 20.0 0.15 12.1 2.7 4.4 3 1 1 4 4 4 3 BED zinc finger zinc_ribbon_15 PF17032.5 OWF36838.1 - 0.00037 21.2 7.5 0.12 13.1 0.8 2.5 2 0 0 2 2 2 2 zinc-ribbon family zf-C2H2_3rep PF18868.1 OWF36838.1 - 0.0007 20.3 12.4 2 9.1 2.6 3.7 1 1 2 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 OWF36838.1 - 0.00084 19.6 13.1 0.0054 17.0 4.6 3.2 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OWF36838.1 - 0.00085 19.6 0.8 0.083 13.3 0.0 4.8 5 0 0 5 5 4 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 OWF36838.1 - 0.0014 18.7 15.3 0.74 10.0 4.8 3.7 2 1 1 3 3 3 3 Zinc ribbon domain XPA_N PF01286.18 OWF36838.1 - 0.0023 17.9 10.5 1.2 9.2 0.2 4.4 4 0 0 4 4 4 1 XPA protein N-terminal Prok-RING_1 PF14446.6 OWF36838.1 - 0.0043 17.0 7.7 5.2 7.1 0.1 4.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-C2HE PF16278.5 OWF36838.1 - 0.0063 16.9 19.2 0.19 12.2 0.5 4.4 1 1 3 4 4 4 1 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 OWF36838.1 - 0.0073 16.1 2.4 2.1 8.2 0.1 2.5 1 1 1 2 2 2 2 GAGA factor HypA PF01155.19 OWF36838.1 - 0.013 15.5 6.7 1.2 9.2 0.7 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.5 OWF36838.1 - 0.015 15.0 20.4 0.39 10.5 2.2 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type HNH PF01844.23 OWF36838.1 - 0.022 14.9 15.5 1.1 9.5 0.7 5.0 5 0 0 5 5 5 0 HNH endonuclease zf-C2H2_2 PF12756.7 OWF36838.1 - 0.024 15.0 17.9 0.98 9.8 0.2 4.3 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 OWF36838.1 - 0.042 13.7 7.1 0.82 9.6 0.1 4.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CpXC PF14353.6 OWF36838.1 - 0.044 13.8 9.2 10 6.2 0.7 4.0 1 1 1 3 3 3 0 CpXC protein zf-LYAR PF08790.11 OWF36838.1 - 0.1 12.5 14.7 3.6 7.6 1.4 4.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger HNH_5 PF14279.6 OWF36838.1 - 0.1 12.5 12.2 2.3 8.1 0.9 4.4 4 1 0 4 4 3 0 HNH endonuclease zf-CHCC PF10276.9 OWF36838.1 - 0.11 12.6 13.3 0.23 11.5 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger domain YhfH PF14149.6 OWF36838.1 - 0.12 12.4 10.1 18 5.4 0.3 4.5 3 1 1 4 4 4 0 YhfH-like protein LIM PF00412.22 OWF36838.1 - 0.34 11.2 13.3 11 6.3 2.1 4.0 1 1 3 4 4 4 0 LIM domain zf-trcl PF13451.6 OWF36838.1 - 0.49 10.3 12.8 8.1 6.4 0.2 4.0 3 1 0 3 3 3 0 Probable zinc-ribbon domain DUF3268 PF11672.8 OWF36838.1 - 0.56 10.6 7.1 1.7 9.0 0.3 2.9 1 1 2 3 3 3 0 zinc-finger-containing domain OrfB_Zn_ribbon PF07282.11 OWF36838.1 - 1.6 8.8 15.1 3.2 7.7 0.7 3.8 1 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-AN1 PF01428.16 OWF36838.1 - 1.8 8.8 26.9 1.1 9.4 0.3 5.1 5 0 0 5 5 4 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 OWF36838.1 - 2.2 8.3 23.3 0.97 9.4 1.0 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 OWF36838.1 - 3.2 6.9 14.6 7.5 5.6 4.9 3.4 1 1 2 3 3 3 0 Putative actin-like family DNA_RNApol_7kD PF03604.13 OWF36838.1 - 4.1 7.2 10.7 3.5 7.4 0.2 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Zf_RING PF16744.5 OWF36838.1 - 4.4 7.5 10.2 7 6.8 0.7 3.8 1 1 2 3 3 3 0 KIAA1045 RING finger ADK_lid PF05191.14 OWF36838.1 - 4.4 7.4 16.4 6.1 6.9 0.0 3.9 3 1 1 4 4 4 0 Adenylate kinase, active site lid Zn_ribbon_recom PF13408.6 OWF36838.1 - 4.7 7.8 18.8 71 4.0 7.1 4.0 1 1 3 4 4 4 0 Recombinase zinc beta ribbon domain TFIIS_C PF01096.18 OWF36838.1 - 4.8 7.1 14.1 9.4 6.2 0.4 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 OWF36838.1 - 7 6.7 17.8 3.7 7.6 0.3 3.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Utp12 PF04003.12 OWF36839.1 - 0.0034 17.7 0.1 0.0063 16.8 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Glyco_transf_10 PF00852.19 OWF36840.1 - 2.5e-46 157.6 0.7 2.5e-46 157.6 0.7 1.7 2 1 1 3 3 3 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF36840.1 - 2.8e-18 66.4 0.3 6.5e-18 65.2 0.3 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Methyltransf_7 PF03492.15 OWF36841.1 - 2.8e-23 82.7 0.1 6.1e-21 75.0 0.0 2.0 1 1 1 2 2 2 2 SAM dependent carboxyl methyltransferase T4_deiodinase PF00837.17 OWF36843.1 - 1.5e-33 116.0 0.0 1.7e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase FokI_C PF02980.16 OWF36844.1 - 0.0024 17.9 1.4 0.24 11.4 0.2 2.1 1 1 1 2 2 2 2 Restriction endonuclease FokI, catalytic domain DUF1986 PF09342.11 OWF36844.1 - 0.041 14.3 0.7 2.5 8.5 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1986) Cu_amine_oxidN1 PF07833.11 OWF36844.1 - 0.067 13.7 1.7 0.89 10.1 1.8 2.3 1 1 0 1 1 1 0 Copper amine oxidase N-terminal domain DUF5335 PF17269.2 OWF36844.1 - 0.21 11.4 1.0 11 5.9 0.1 2.4 1 1 2 3 3 3 0 Family of unknown function (DUF5335) Inhibitor_I78 PF11720.8 OWF36844.1 - 1.6 8.9 4.9 14 5.8 1.2 2.6 1 1 1 2 2 2 0 Peptidase inhibitor I78 family DUF4717 PF15838.5 OWF36844.1 - 1.7 8.7 3.5 33 4.6 0.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4717) FokI_C PF02980.16 OWF36845.1 - 0.0011 19.0 1.5 1.3 9.0 0.1 2.9 1 1 3 4 4 4 4 Restriction endonuclease FokI, catalytic domain Cu_amine_oxidN1 PF07833.11 OWF36845.1 - 0.016 15.7 0.2 1.1 9.7 0.2 2.9 1 1 0 1 1 1 0 Copper amine oxidase N-terminal domain DUF4352 PF11611.8 OWF36845.1 - 0.045 14.0 1.3 4 7.7 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4352) TAA-Trp-ring PF15401.6 OWF36845.1 - 0.059 13.8 0.2 29 5.2 0.1 4.2 2 2 2 4 4 4 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin LLGL PF08366.13 OWF36845.1 - 0.39 11.1 10.3 11 6.4 0.4 3.2 1 1 2 3 3 3 0 LLGL2 FtsA PF14450.6 OWF36845.1 - 0.51 10.8 6.6 6.3 7.3 0.6 3.1 1 1 1 2 2 2 0 Cell division protein FtsA FokI_C PF02980.16 OWF36846.1 - 3.2e-05 24.0 1.7 0.22 11.6 0.1 3.0 1 1 2 3 3 3 3 Restriction endonuclease FokI, catalytic domain Cu_amine_oxidN1 PF07833.11 OWF36846.1 - 0.001 19.5 0.7 0.45 11.0 0.7 2.9 1 1 0 1 1 1 1 Copper amine oxidase N-terminal domain DUF4352 PF11611.8 OWF36846.1 - 0.0059 16.9 2.1 5.4 7.3 0.1 3.1 2 1 0 3 3 3 2 Domain of unknown function (DUF4352) DUF5335 PF17269.2 OWF36846.1 - 0.017 15.0 1.0 2.8 7.8 0.1 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5335) FtsA PF14450.6 OWF36846.1 - 0.19 12.2 8.3 1.8e+02 2.6 8.3 3.7 1 1 0 1 1 1 0 Cell division protein FtsA Ntox15 PF15604.6 OWF36846.1 - 0.33 11.1 2.7 55 3.9 2.7 3.5 1 1 0 1 1 1 0 Novel toxin 15 AIDA PF16168.5 OWF36846.1 - 0.41 10.8 6.8 1.4 9.1 0.6 3.1 1 1 1 3 3 3 0 Adhesin of bacterial autotransporter system, probable stalk LLGL PF08366.13 OWF36846.1 - 1.2 9.5 5.7 2.1e+02 2.3 5.7 3.3 1 1 0 1 1 1 0 LLGL2 gpW PF02831.15 OWF36846.1 - 3.9 7.5 10.4 3.8 7.5 0.2 4.3 1 1 3 4 4 4 0 gpW RNA_pol_Rpc4 PF05132.14 OWF36846.1 - 6.3 7.2 5.7 77 3.7 0.2 3.8 1 1 1 3 3 3 0 RNA polymerase III RPC4 BNIP3 PF06553.12 OWF36847.1 - 0.019 14.7 0.4 0.019 14.7 0.4 1.4 2 0 0 2 2 2 0 BNIP3 COesterase PF00135.28 OWF36849.1 - 1.3e-125 420.2 0.0 1.5e-125 420.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF36849.1 - 2.3e-07 30.9 0.1 1.1e-06 28.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold YbbR PF07949.12 OWF36850.1 - 0.036 14.4 36.5 0.21 12.0 1.1 6.7 2 2 2 5 5 5 0 YbbR-like protein Bactofilin PF04519.13 OWF36851.1 - 4e-14 52.7 65.8 1.2e-05 25.5 3.4 7.9 3 3 6 9 9 9 8 Polymer-forming cytoskeletal DUF5437 PF17505.2 OWF36852.1 - 0.58 10.2 3.1 0.63 10.1 0.1 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5437) DUF4983 PF16356.5 OWF36854.1 - 0.15 12.9 1.7 7.1 7.5 0.0 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4983) FAP PF07174.11 OWF36854.1 - 1.8 8.0 4.9 1.9 7.8 4.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Colipase-like PF15083.6 OWF36857.1 - 0.71 10.0 4.8 6.5 6.9 0.3 2.3 2 0 0 2 2 2 0 Colipase-like Colipase-like PF15083.6 OWF36858.1 - 0.23 11.6 2.0 0.46 10.6 1.0 1.8 1 1 0 1 1 1 0 Colipase-like DUF4983 PF16356.5 OWF36858.1 - 1.6 9.6 5.1 17 6.3 0.8 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4983) Colipase-like PF15083.6 OWF36859.1 - 0.15 12.2 2.5 0.13 12.4 1.3 1.6 1 1 0 1 1 1 0 Colipase-like DUF4983 PF16356.5 OWF36859.1 - 0.39 11.6 4.8 2.4 9.0 0.4 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4983) Cornifin PF02389.15 OWF36860.1 - 6.6e-09 36.1 0.9 0.0054 16.9 0.0 3.4 1 1 1 3 3 3 3 Cornifin (SPRR) family SNF PF00209.18 OWF36864.1 - 1e-48 166.3 11.0 6.6e-43 147.2 6.0 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DctQ PF04290.12 OWF36864.1 - 0.14 12.1 8.2 0.3 11.0 8.2 1.6 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component PIRT PF15099.6 OWF36864.1 - 1.5 8.4 6.3 1.1 8.8 0.8 2.5 1 1 2 3 3 3 0 Phosphoinositide-interacting protein family 7TM_GPCR_Srw PF10324.9 OWF36865.1 - 5.7e-11 42.3 4.5 6.6e-11 42.1 4.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF36865.1 - 0.0029 17.0 3.3 0.0037 16.6 3.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AKAP7_RIRII_bdg PF10470.9 OWF36866.1 - 0.0037 17.3 0.0 2.5 8.3 0.0 2.7 2 0 0 2 2 2 2 PKA-RI-RII subunit binding domain of A-kinase anchor protein Bacillus_HBL PF05791.11 OWF36866.1 - 0.0084 16.0 7.3 0.0097 15.7 0.7 3.0 3 1 0 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) SLATT_fungal PF18142.1 OWF36866.1 - 0.012 15.6 0.3 4.1 7.4 0.0 3.4 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain HBD PF18534.1 OWF36866.1 - 0.016 15.3 1.1 0.68 10.1 0.1 2.7 2 0 0 2 2 2 0 Helical bundle domain HTH_50 PF18024.1 OWF36866.1 - 0.049 13.2 0.2 0.17 11.6 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RHH_6 PF16762.5 OWF36867.1 - 0.11 13.1 1.1 0.11 13.1 1.1 2.8 1 1 2 3 3 3 0 Ribbon-helix-helix domain DUF3528 PF12045.8 OWF36872.1 - 0.5 11.0 1.7 3.2 8.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3528) Ribosomal_L9_C PF03948.14 OWF36873.1 - 4.9e-09 36.5 21.4 1.2 9.6 1.0 7.4 1 1 6 7 7 7 5 Ribosomal protein L9, C-terminal domain Glyco_hydro_2 PF00703.21 OWF36873.1 - 1.1e-07 32.5 33.8 0.1 13.3 3.7 5.9 1 1 5 6 6 6 6 Glycosyl hydrolases family 2 bMG5 PF17972.1 OWF36873.1 - 6.6e-06 26.5 1.8 4.7 7.6 0.0 5.0 1 1 6 7 7 7 2 Bacterial Alpha-2-macroglobulin MG5 domain AbiEii PF08843.11 OWF36873.1 - 0.0023 17.9 4.6 1.2 9.0 0.1 3.5 1 1 1 2 2 2 2 Nucleotidyl transferase AbiEii toxin, Type IV TA system SVA PF05326.11 OWF36873.1 - 0.0074 16.3 16.3 2.1 8.3 0.8 5.0 1 1 4 5 5 5 2 Seminal vesicle autoantigen (SVA) Arm-DNA-bind_5 PF17293.2 OWF36873.1 - 0.055 13.9 16.9 0.21 12.0 2.2 4.3 1 1 2 3 3 3 0 Arm DNA-binding domain DUF4360 PF14273.6 OWF36873.1 - 0.19 11.6 0.8 6.4 6.6 0.1 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4360) DUF2483 PF10656.9 OWF36873.1 - 0.33 11.2 29.7 7.6 6.8 0.4 8.1 1 1 6 8 8 8 0 Hypothetical protein of unknown function (DUF2483) DUF3656 PF12392.8 OWF36873.1 - 9.3 6.9 10.3 1.7e+02 2.9 0.6 4.0 1 1 1 2 2 2 0 Collagenase DUF1664 PF07889.12 OWF36874.1 - 0.00055 20.0 9.0 0.0015 18.6 2.4 3.0 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 OWF36874.1 - 0.0015 18.5 1.7 0.0015 18.5 1.7 3.8 4 1 1 5 5 4 1 bZIP transcription factor Tropomyosin_1 PF12718.7 OWF36874.1 - 0.0023 18.1 8.7 0.0037 17.4 6.7 2.2 1 1 1 2 2 2 1 Tropomyosin like LXG PF04740.12 OWF36874.1 - 0.0031 17.3 3.3 0.0031 17.3 3.3 1.8 2 0 0 2 2 2 1 LXG domain of WXG superfamily Spc7 PF08317.11 OWF36874.1 - 0.0041 16.1 8.0 0.009 14.9 7.5 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein Fez1 PF06818.15 OWF36874.1 - 0.0055 17.2 8.7 0.0055 17.2 8.7 1.9 1 1 1 2 2 2 1 Fez1 LPP PF04728.13 OWF36874.1 - 0.01 16.2 2.9 2.2 8.8 0.1 3.9 1 1 2 3 3 3 0 Lipoprotein leucine-zipper DHR10 PF18595.1 OWF36874.1 - 0.011 15.8 4.9 0.018 15.1 3.5 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain SlyX PF04102.12 OWF36874.1 - 0.023 15.3 0.2 0.14 12.8 0.1 2.4 2 1 0 2 2 2 0 SlyX XhlA PF10779.9 OWF36874.1 - 0.024 14.8 5.2 0.024 14.8 5.2 3.2 3 0 0 3 3 3 0 Haemolysin XhlA DUF4988 PF16378.5 OWF36874.1 - 0.032 13.9 1.9 0.051 13.3 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function GARP PF16731.5 OWF36874.1 - 0.04 13.6 3.7 1.1 8.9 0.2 2.4 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF4164 PF13747.6 OWF36874.1 - 0.47 10.8 6.4 0.9 9.9 2.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DASH_Spc19 PF08287.11 OWF36874.1 - 0.68 9.8 8.1 0.092 12.6 3.9 1.8 2 0 0 2 2 2 0 Spc19 CLZ PF16526.5 OWF36874.1 - 0.71 10.3 12.7 0.15 12.5 2.1 4.1 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 OWF36874.1 - 1.1 9.7 7.5 0.42 11.1 0.6 3.2 2 1 1 3 3 3 0 Snapin/Pallidin ZapB PF06005.12 OWF36874.1 - 1.1 9.7 7.4 0.88 10.1 4.0 2.7 2 1 0 2 2 1 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 OWF36874.1 - 1.2 9.7 7.0 2.5 8.7 3.6 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 OWF36874.1 - 1.3 9.4 10.1 0.29 11.4 3.4 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 OWF36874.1 - 1.4 8.7 15.5 0.16 11.8 8.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) NPV_P10 PF05531.12 OWF36874.1 - 1.8 9.1 12.3 0.2 12.2 1.3 3.3 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 OWF36874.1 - 2.5 8.6 14.7 0.069 13.6 5.2 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 OWF36874.1 - 5 6.6 8.8 0.66 9.5 3.0 2.4 2 1 1 3 3 2 0 fzo-like conserved region FlaC_arch PF05377.11 OWF36874.1 - 5.9 7.4 13.8 0.44 11.0 4.1 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 OWF36874.1 - 6.2 7.0 12.7 0.51 10.5 5.8 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family UPF0449 PF15136.6 OWF36874.1 - 8.7 6.9 9.0 26 5.3 6.1 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Arf PF00025.21 OWF36876.1 - 4.3e-12 45.8 0.0 4.6e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF36876.1 - 0.033 13.6 0.0 0.033 13.6 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF36876.1 - 0.055 13.6 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 OWF36876.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.9 OWF36876.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Y_phosphatase PF00102.27 OWF36877.1 - 1.5e-30 106.5 0.0 1.6e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF36877.1 - 3.4e-06 27.2 0.0 3.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OWF36877.1 - 5.6e-05 23.0 0.1 7.9e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF36877.1 - 0.0013 18.9 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 OWF36877.1 - 0.077 12.6 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family 7tm_1 PF00001.21 OWF36878.1 - 2e-42 145.3 7.8 2.5e-42 145.0 7.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF36878.1 - 0.0013 18.5 13.3 0.002 17.9 13.2 1.3 1 1 0 1 1 1 1 Olfactory receptor GPHH PF16905.5 OWF36878.1 - 3.3 7.5 4.9 5.4 6.9 0.7 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Git3 PF11710.8 OWF36878.1 - 5.3 6.8 20.4 15 5.2 20.4 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 BEN PF10523.9 OWF36879.1 - 0.064 13.5 0.0 0.088 13.1 0.0 1.4 1 1 0 1 1 1 0 BEN domain Mab-21 PF03281.14 OWF36880.1 - 0.0021 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_1 PF00515.28 OWF36881.1 - 0.011 15.5 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF36881.1 - 0.016 15.5 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NTNH_C PF08470.10 OWF36884.1 - 0.015 15.2 6.0 3 7.7 0.3 4.1 1 1 4 5 5 5 0 Nontoxic nonhaemagglutinin C-terminal 7tm_2 PF00002.24 OWF36885.1 - 2e-08 33.8 17.9 2.9e-08 33.3 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) IRK PF01007.20 OWF36885.1 - 7.4 6.4 10.4 18 5.1 10.0 2.0 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain 7tm_1 PF00001.21 OWF36886.1 - 3.4e-28 98.7 13.4 4.3e-28 98.4 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF36886.1 - 1.1e-10 41.6 17.7 1.6e-10 41.1 17.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF36886.1 - 0.00068 19.1 13.8 0.0018 17.7 13.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 OWF36886.1 - 0.011 15.5 10.8 0.016 15.0 10.3 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 SBP_bac_3 PF00497.20 OWF36887.1 - 0.00017 21.1 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Hpre_diP_synt_I PF07456.11 OWF36888.1 - 0.025 14.6 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I Cofilin_ADF PF00241.20 OWF36889.1 - 1.4e-06 28.1 0.1 1.5e-06 28.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CTP_transf_3 PF02348.19 OWF36889.1 - 0.051 13.5 0.0 0.061 13.2 0.0 1.0 1 0 0 1 1 1 0 Cytidylyltransferase IBR PF01485.21 OWF36890.1 - 2.8e-06 27.5 8.0 2.8e-06 27.5 8.0 2.4 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 OWF36890.1 - 2.7 8.2 18.8 5 7.4 11.4 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Beta_helix_2 PF18835.1 OWF36891.1 - 8.8e-06 25.4 4.5 25 4.7 0.1 5.9 4 2 2 6 6 6 1 Beta helix repeat of Inulin fructotransferase Centro_C10orf90 PF17730.1 OWF36891.1 - 0.00049 19.0 0.1 28 3.3 0.0 5.2 6 0 0 6 6 6 2 Centrosomal C10orf90 UPF0051 PF01458.17 OWF36891.1 - 0.00067 19.4 0.0 7 6.3 0.0 3.9 1 1 2 3 3 3 2 Uncharacterized protein family (UPF0051) LBP_C PF17386.2 OWF36891.1 - 0.00081 19.2 48.9 23 5.0 0.1 14.1 8 3 7 15 15 15 5 Lacto-N-biose phosphorylase C-terminal domain DUF951 PF06107.11 OWF36891.1 - 0.053 13.4 13.3 45 4.1 0.1 6.7 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF951) DUF4722 PF15849.5 OWF36891.1 - 0.06 13.1 2.4 27 4.4 0.0 4.0 2 2 4 6 6 6 0 Domain of unknown function (DUF4722) Beta_helix_2 PF18835.1 OWF36892.1 - 8.1e-08 31.9 5.1 45 3.9 0.0 8.2 7 1 1 8 8 8 0 Beta helix repeat of Inulin fructotransferase Centro_C10orf90 PF17730.1 OWF36892.1 - 1.1e-07 31.1 1.7 24 3.5 0.0 8.5 9 0 0 9 9 9 1 Centrosomal C10orf90 Glyco_hydro_32C PF08244.12 OWF36892.1 - 1.9e-07 31.2 9.0 19 5.2 0.3 10.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 32 C terminal DUF951 PF06107.11 OWF36892.1 - 0.04 13.8 29.1 74 3.4 0.0 11.1 8 2 0 11 11 11 0 Bacterial protein of unknown function (DUF951) DUF1314 PF07013.11 OWF36892.1 - 0.45 10.4 14.5 9.3 6.1 0.1 5.7 1 1 5 6 6 6 0 Protein of unknown function (DUF1314) LBP_C PF17386.2 OWF36892.1 - 2.4 8.1 110.2 48 3.9 0.1 28.3 22 9 10 32 32 32 0 Lacto-N-biose phosphorylase C-terminal domain DAGK_prokar PF01219.19 OWF36894.1 - 0.0014 18.4 3.5 0.19 11.5 0.2 3.7 1 1 4 5 5 5 1 Prokaryotic diacylglycerol kinase HCV_NS4b PF01001.19 OWF36894.1 - 0.0044 16.7 1.1 0.17 11.5 0.2 2.0 1 1 1 2 2 2 1 Hepatitis C virus non-structural protein NS4b SAM_adeno_trans PF01887.16 OWF36894.1 - 0.015 14.7 1.4 1.2 8.5 0.1 2.1 1 1 1 2 2 2 0 S-adenosyl-l-methionine hydroxide adenosyltransferase MatK_N PF01824.18 OWF36894.1 - 0.022 14.4 2.5 2.9 7.5 0.4 2.8 1 1 2 3 3 3 0 MatK/TrnK amino terminal region YbgT_YccB PF08173.11 OWF36894.1 - 0.072 13.2 0.1 82 3.5 0.0 3.4 3 0 0 3 3 3 0 Membrane bound YbgT-like protein Phage_holin_2_3 PF16080.5 OWF36894.1 - 0.27 11.0 3.2 2.6 7.9 0.6 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 TetR_C_10 PF16295.5 OWF36894.1 - 0.34 11.2 3.5 18 5.6 0.1 3.0 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF2953 PF11167.8 OWF36894.1 - 1.1 9.4 4.6 56 3.9 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2953) Pro_sub2 PF18513.1 OWF36894.1 - 1.5 9.0 4.7 6.6 7.0 0.6 2.8 1 1 1 2 2 2 0 Prodomain subtilisin 2 Galactosyl_T PF01762.21 OWF36895.1 - 1.6e-39 135.7 0.0 2.5e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Borrelia_rep PF03183.13 OWF36897.1 - 0.037 14.0 31.0 87 3.4 0.0 11.5 12 0 0 12 12 12 0 Borrelia repeat protein TMEM135_C_rich PF15982.5 OWF36898.1 - 1.4e-28 100.1 0.2 1.6e-28 100.0 0.2 1.0 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF4983 PF16356.5 OWF36900.1 - 1.4 9.8 4.8 21 6.0 0.2 3.6 1 1 2 4 4 4 0 Domain of unknown function (DUF4983) FAP PF07174.11 OWF36900.1 - 8.7 5.7 8.7 12 5.2 8.7 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Neur_chan_LBD PF02931.23 OWF36901.1 - 5.4e-38 130.6 0.1 7.2e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF36901.1 - 5.8e-12 46.2 9.5 5.8e-12 46.2 9.5 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Arrestin_C PF02752.22 OWF36902.1 - 1.6e-17 64.2 0.0 1.1e-16 61.5 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF36902.1 - 6.5e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OWF36902.1 - 0.0031 16.8 0.0 0.049 12.8 0.0 2.1 2 0 0 2 2 2 1 Rgp1 YicC_N PF03755.13 OWF36902.1 - 0.072 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 YicC-like family, N-terminal region RPN5_C PF18098.1 OWF36903.1 - 1.1e-18 67.1 6.7 2.7e-18 65.8 6.7 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 OWF36903.1 - 2.5e-18 66.5 0.2 4.8e-18 65.6 0.1 1.5 2 0 0 2 2 2 1 PCI domain Birna_RdRp PF04197.12 OWF36903.1 - 0.0011 17.4 0.5 0.0013 17.1 0.5 1.0 1 0 0 1 1 1 1 Birnavirus RNA dependent RNA polymerase (VP1) PMT2_N PF17987.1 OWF36904.1 - 4.2e-05 23.7 2.5 6.9 6.9 0.1 4.6 1 1 3 4 4 4 3 Phosphoethanolamine N-methyltransferase 2 N-terminal DUF150 PF02576.17 OWF36904.1 - 0.012 16.0 0.1 6.3 7.3 0.0 3.5 3 1 0 3 3 3 0 RimP N-terminal domain Pribosyltran_N PF13793.6 OWF36904.1 - 0.032 14.2 0.0 7.6 6.5 0.0 2.6 1 1 2 3 3 3 0 N-terminal domain of ribose phosphate pyrophosphokinase Shigella_OspC PF06128.11 OWF36904.1 - 0.1 12.3 0.2 78 2.8 0.0 3.8 1 1 3 4 4 4 0 Shigella flexneri OspC protein Borrelia_rep PF03183.13 OWF36905.1 - 0.92 9.6 13.7 66 3.8 0.0 7.1 9 0 0 9 9 9 0 Borrelia repeat protein Neisseria_TspB PF05616.13 OWF36905.1 - 3.1 6.2 5.3 8.4 4.7 0.1 2.0 1 1 1 2 2 2 0 Neisseria meningitidis TspB protein YojJ PF10372.9 OWF36906.1 - 0.0015 18.6 0.9 0.002 18.2 0.9 1.2 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Laminin_II PF06009.12 OWF36906.1 - 0.0022 18.0 4.3 0.0024 17.9 4.3 1.0 1 0 0 1 1 1 1 Laminin Domain II TolA_bind_tri PF16331.5 OWF36906.1 - 0.01 15.9 3.8 0.014 15.5 3.6 1.3 1 1 0 1 1 1 0 TolA binding protein trimerisation Trimer_CC PF08954.11 OWF36906.1 - 0.026 14.1 0.6 1.3 8.6 0.0 2.3 1 1 1 2 2 2 0 Trimerisation motif Dynamin_M PF01031.20 OWF36906.1 - 0.026 13.7 2.8 0.03 13.6 2.8 1.0 1 0 0 1 1 1 0 Dynamin central region DUF5344 PF17279.2 OWF36906.1 - 0.027 15.0 3.5 0.034 14.7 3.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5344) ZapD PF07072.11 OWF36906.1 - 0.034 13.9 2.8 0.035 13.8 2.8 1.0 1 0 0 1 1 1 0 Cell division protein DUF1664 PF07889.12 OWF36906.1 - 0.047 13.7 0.7 0.058 13.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.9 OWF36906.1 - 0.047 13.9 5.2 0.064 13.5 5.2 1.2 1 0 0 1 1 1 0 Haemolysin XhlA Snapin_Pallidin PF14712.6 OWF36906.1 - 0.05 14.0 4.2 0.077 13.4 4.2 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Occludin_ELL PF07303.13 OWF36906.1 - 0.06 14.1 1.8 0.076 13.7 1.8 1.2 1 0 0 1 1 1 0 Occludin homology domain OmpH PF03938.14 OWF36906.1 - 0.065 13.6 2.6 0.075 13.4 2.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF745 PF05335.13 OWF36906.1 - 0.072 12.8 2.0 0.071 12.8 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) HIP1_clath_bdg PF16515.5 OWF36906.1 - 0.084 13.5 5.7 0.11 13.1 5.7 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COG5 PF10392.9 OWF36906.1 - 0.22 11.7 5.5 0.24 11.6 5.5 1.0 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 OWF36906.1 - 0.66 10.4 6.1 2.6 8.5 0.2 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 OWF36906.1 - 0.8 9.2 4.0 0.83 9.2 4.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit EMP24_GP25L PF01105.24 OWF36906.1 - 0.97 9.4 6.1 4.3 7.2 6.1 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Acyl-CoA_dh_1 PF00441.24 OWF36907.1 - 7.9e-09 35.9 1.6 5.7e-08 33.1 0.2 2.0 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OWF36907.1 - 3.2e-07 30.5 0.0 6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Jnk-SapK_ap_N PF09744.9 OWF36909.1 - 7.1e-22 78.3 4.3 7.9e-22 78.2 4.3 1.0 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DHR10 PF18595.1 OWF36909.1 - 0.016 15.2 3.5 0.023 14.7 3.5 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF4337 PF14235.6 OWF36909.1 - 0.039 14.1 0.3 0.039 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2115 PF09888.9 OWF36909.1 - 0.049 14.2 0.6 0.055 14.0 0.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DPRP PF04244.13 OWF36909.1 - 0.051 13.4 0.1 0.058 13.3 0.1 1.0 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein ZapB PF06005.12 OWF36909.1 - 0.093 13.2 8.2 0.14 12.6 8.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB 4HBT PF03061.22 OWF36911.1 - 4.7e-14 52.5 0.2 6.4e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OWF36911.1 - 5.3e-05 23.6 0.0 5.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 OWF36911.1 - 0.00013 22.1 0.2 0.00015 21.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) SPDY PF03771.16 OWF36913.1 - 1.4 8.9 4.4 17 5.5 4.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF317) NCD1 PF04904.13 OWF36914.1 - 0.18 11.8 0.1 12 6.0 0.1 2.9 1 1 1 3 3 3 0 NAB conserved region 1 (NCD1) Toast_rack_N PF17115.5 OWF36914.1 - 9.3 6.6 10.7 11 6.4 3.0 2.9 1 1 2 3 3 3 0 N-terminal domain of toast_rack, DUF2154 Phage_T4_Ndd PF06591.11 OWF36915.1 - 0.17 11.7 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Lectin_C PF00059.21 OWF36916.1 - 4e-12 46.8 0.1 2.9e-11 44.0 0.0 2.1 2 1 0 2 2 2 1 Lectin C-type domain Sushi PF00084.20 OWF36916.1 - 1.8e-09 38.0 0.2 7.8e-09 36.0 0.1 2.0 1 1 1 2 2 2 1 Sushi repeat (SCR repeat) IgGFc_binding PF17517.2 OWF36917.1 - 1.3e-36 126.4 0.2 3.1e-36 125.1 0.1 1.6 2 0 0 2 2 2 1 IgGFc binding protein Mito_carr PF00153.27 OWF36918.1 - 1e-21 76.7 0.1 3.3e-20 71.8 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein GAPT PF11770.8 OWF36920.1 - 0.01 15.7 1.3 20 5.0 0.1 4.0 1 1 2 4 4 4 0 GRB2-binding adapter (GAPT) ocr PF08684.10 OWF36920.1 - 0.13 12.7 0.1 16 6.1 0.0 3.0 2 1 1 3 3 3 0 DNA mimic ocr DUF2779 PF11074.8 OWF36920.1 - 0.34 11.4 5.4 14 6.2 0.2 4.0 1 1 3 4 4 4 0 Domain of unknown function(DUF2779) Pih1_fungal_CS PF18482.1 OWF36920.1 - 4.3 7.9 5.9 44 4.7 1.9 3.8 1 1 2 3 3 3 0 Fungal Pih1 CS domain 7tm_1 PF00001.21 OWF36921.1 - 1.6e-10 40.8 27.2 2.8e-10 40.0 27.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF36921.1 - 0.00016 21.2 26.3 0.00021 20.7 25.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF36921.1 - 0.019 14.6 28.3 0.015 14.9 25.1 2.4 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF5570 PF17731.1 OWF36923.1 - 0.0088 16.1 0.0 0.93 9.6 0.0 2.3 2 1 0 2 2 2 2 Family of unknown function (DUF5570) SPDY PF03771.16 OWF36923.1 - 0.055 13.4 0.4 5.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF317) NolB PF17398.2 OWF36925.1 - 9.5e-06 26.1 0.1 69 3.8 0.0 6.6 1 1 6 7 7 7 2 Nodulation protein NolB QSregVF_b PF12843.7 OWF36925.1 - 0.017 15.0 0.7 45 4.0 0.1 3.8 3 0 0 3 3 3 0 Putative quorum-sensing-regulated virulence factor NAP PF00956.18 OWF36926.1 - 4.5e-06 26.0 3.0 5.4e-05 22.5 0.6 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 OWF36926.1 - 0.0025 17.8 0.7 0.0032 17.4 0.7 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Hemagglutinin PF00509.18 OWF36926.1 - 0.064 11.6 0.3 0.07 11.5 0.3 1.0 1 0 0 1 1 1 0 Haemagglutinin Acetyltransf_18 PF18014.1 OWF36927.1 - 9.1e-21 74.0 0.0 1.2e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF36927.1 - 0.0036 17.2 0.0 0.034 14.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FAD_syn PF06574.12 OWF36927.1 - 0.049 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase BIR PF00653.21 OWF36928.1 - 1.2e-17 64.3 0.1 1.5e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Fic PF02661.18 OWF36929.1 - 8.5e-25 87.5 0.1 2.3e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 Fic/DOC family TPR_1 PF00515.28 OWF36929.1 - 4.3e-08 32.7 0.3 0.0035 17.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF36929.1 - 5.2e-08 32.4 0.3 8.4e-05 22.4 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF36929.1 - 3.5e-06 27.2 1.2 1.2e-05 25.5 0.7 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF36929.1 - 1.3e-05 25.6 0.1 0.012 16.4 0.0 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF36929.1 - 0.00018 21.1 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.6 OWF36929.1 - 0.00022 21.0 0.5 0.051 13.5 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF36929.1 - 0.00022 21.4 0.1 0.0019 18.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 OWF36929.1 - 0.00084 19.4 1.2 0.0063 16.6 0.3 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 OWF36929.1 - 0.00092 19.8 0.0 0.0021 18.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF36929.1 - 0.0042 17.2 0.3 0.19 12.0 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF36929.1 - 0.0097 16.4 0.1 0.024 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF36929.1 - 0.037 14.1 0.1 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ERG4_ERG24 PF01222.17 OWF36930.1 - 3.6e-66 223.7 18.8 4.3e-66 223.5 18.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OWF36930.1 - 7.1e-05 22.4 0.4 0.00015 21.4 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Homeobox_KN PF05920.11 OWF36931.1 - 1.6e-11 43.9 0.0 2.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF36931.1 - 7.7e-05 22.5 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF36931.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Phi-29_GP4 PF05464.11 OWF36931.1 - 0.022 15.1 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Ribosomal_L2 PF00181.23 OWF36932.1 - 0.00025 20.9 0.5 4.5 7.3 0.0 5.0 2 1 4 7 7 7 1 Ribosomal Proteins L2, RNA binding domain Phage_sheath_1N PF17481.2 OWF36932.1 - 0.00092 19.7 14.6 3.7e+03 -1.6 14.6 4.3 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain PT-HINT PF07591.11 OWF36932.1 - 0.0012 19.1 5.8 1.9 8.7 0.0 4.0 1 1 4 5 5 5 1 Pretoxin HINT domain HPIP_like PF18524.1 OWF36932.1 - 0.24 11.2 11.6 33 4.3 0.0 5.5 5 2 3 8 8 8 0 High potential iron-sulfur protein like Flagellar_put PF12611.8 OWF36932.1 - 0.52 10.1 3.5 37 4.2 0.0 5.2 7 1 0 7 7 7 0 Putative flagellar GrpE PF01025.19 OWF36932.1 - 0.81 9.3 8.1 2.2 7.9 0.5 4.5 3 2 4 7 7 7 0 GrpE Rsm22 PF09243.10 OWF36932.1 - 0.99 8.6 3.8 91 2.2 0.1 3.8 1 1 3 4 4 4 0 Mitochondrial small ribosomal subunit Rsm22 C6 PF01681.17 OWF36932.1 - 2.6 8.7 12.2 7.7 7.1 0.4 4.0 1 1 3 4 4 4 0 C6 domain SymE_toxin PF08845.10 OWF36932.1 - 3.6 7.7 10.6 70 3.6 0.0 6.6 3 3 5 10 10 10 0 Toxin SymE, type I toxin-antitoxin system Galactosyl_T PF01762.21 OWF36933.1 - 1.5e-39 135.8 0.0 2.3e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_hydro_1 PF00232.18 OWF36934.1 - 2.2e-19 69.3 0.0 2.4e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 OWF36935.1 - 3.8e-89 299.2 6.5 4.9e-39 134.0 0.4 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 1 EGF PF00008.27 OWF36936.1 - 0.00021 21.5 0.8 0.00038 20.7 0.8 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_3 PF12947.7 OWF36936.1 - 0.13 12.5 2.6 0.26 11.5 2.6 1.5 1 0 0 1 1 1 0 EGF domain IgGFc_binding PF17517.2 OWF36937.1 - 2.7e-10 40.0 6.9 3e-10 39.9 6.9 1.0 1 0 0 1 1 1 1 IgGFc binding protein DUF4871 PF16167.5 OWF36937.1 - 0.036 14.1 1.8 0.053 13.5 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4871) SHIPPO-rpt PF07004.12 OWF36938.1 - 1.4e-10 41.5 9.3 4.5e-05 24.2 0.2 3.2 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat Trypan_PARP PF05887.11 OWF36939.1 - 0.00068 19.6 51.5 1.8e+04 -7.6 51.5 2.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CIDR1_gamma PF18562.1 OWF36940.1 - 0.043 13.9 19.9 21 5.3 1.2 6.1 2 1 4 6 6 6 0 Cysteine-Rich Interdomain Region 1 gamma DUF333 PF03891.15 OWF36940.1 - 0.11 12.7 11.4 2.2 8.5 0.1 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF333) Laminin_EGF PF00053.24 OWF36940.1 - 9.3 6.5 12.8 44 4.3 3.8 3.3 1 1 1 2 2 2 0 Laminin EGF domain C1q PF00386.21 OWF36941.1 - 3.9e-15 56.2 0.0 4.4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF36941.1 - 0.042 13.8 1.1 0.05 13.5 1.1 1.1 1 0 0 1 1 1 0 BclA C-terminal domain CBM_14 PF01607.24 OWF36942.1 - 6.6e-10 39.0 4.5 8.4e-10 38.7 4.5 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Ribosomal_L3 PF00297.22 OWF36944.1 - 1.7e-184 613.0 10.1 1.9e-184 612.9 10.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Big_3_3 PF13750.6 OWF36944.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Tho1_MOS11_C PF18592.1 OWF36944.1 - 0.71 9.7 3.9 0.54 10.1 0.7 2.4 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain HECT PF00632.25 OWF36945.1 - 3e-09 36.8 0.0 3.6e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Spermine_synt_N PF17284.2 OWF36946.1 - 2.9e-13 49.5 0.5 34 4.4 0.0 11.6 4 2 10 15 15 15 1 Spermidine synthase tetramerisation domain DUF2415 PF10313.9 OWF36946.1 - 4.2e-10 39.4 10.8 32 4.6 0.0 12.6 4 4 8 12 12 12 1 Uncharacterised protein domain (DUF2415) DNA_pol_B_N PF18094.1 OWF36946.1 - 9.9e-05 22.8 17.8 42 4.7 0.1 10.1 1 1 10 13 13 13 0 DNA polymerase beta N-terminal domain Gelsolin PF00626.22 OWF36946.1 - 0.00013 21.7 2.1 51 3.9 0.0 6.8 3 2 4 7 7 7 0 Gelsolin repeat Phage_fiber_C PF06820.12 OWF36946.1 - 2.6 8.5 11.3 17 5.9 0.0 5.3 1 1 3 6 6 6 0 Putative prophage tail fibre C-terminus Ribosomal_L4 PF00573.22 OWF36947.1 - 1.1e-41 142.7 0.2 1.1e-41 142.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OWF36947.1 - 1e-29 102.4 2.0 6.2e-29 99.9 1.1 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain BIR PF00653.21 OWF36948.1 - 9.2e-13 48.6 0.1 1.4e-12 48.1 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain DDE_Tnp_4 PF13359.6 OWF36949.1 - 0.00065 19.4 0.1 0.0012 18.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Thx PF17070.5 OWF36949.1 - 3.9 7.7 5.6 1.5 9.1 1.2 2.2 2 0 0 2 2 2 0 30S ribosomal protein Thx AzlC PF03591.14 OWF36950.1 - 0.019 15.4 9.9 1.1 9.7 0.1 3.0 2 1 0 2 2 2 0 AzlC protein OATP PF03137.20 OWF36951.1 - 0.00019 19.9 1.3 0.00019 19.9 1.3 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family 7tm_1 PF00001.21 OWF36951.1 - 0.037 13.4 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3504 PF12012.8 OWF36952.1 - 1.9e-07 31.2 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) GSH_synth_ATP PF03917.17 OWF36952.1 - 0.036 12.8 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain THAP PF05485.12 OWF36954.1 - 3.4e-11 43.9 1.4 3.9e-11 43.7 1.4 1.0 1 0 0 1 1 1 1 THAP domain WD40 PF00400.32 OWF36956.1 - 8.7e-07 29.5 0.8 0.00063 20.5 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat bPH_3 PF14470.6 OWF36957.1 - 0.23 11.8 2.2 1.3 9.4 1.3 2.5 1 1 1 2 2 2 0 Bacterial PH domain Cas_APE2256 PF09651.10 OWF36960.1 - 0.00017 21.5 0.0 27 4.6 0.0 5.9 1 1 5 7 7 7 1 CRISPR-associated protein (Cas_APE2256) Alpha-amyl_C PF09071.10 OWF36960.1 - 0.0006 19.6 12.5 3.1 7.7 0.0 6.2 1 1 8 9 9 9 3 Alpha-amylase, C terminal Cyclophil_like PF04126.13 OWF36960.1 - 0.016 15.0 0.0 4.4 7.2 0.0 2.8 3 0 0 3 3 3 0 Cyclophilin-like Gal-3-0_sulfotr PF06990.11 OWF36961.1 - 4.5e-09 35.7 0.1 5.8e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase DsbC_N PF10411.9 OWF36962.1 - 4.1 6.9 9.2 3.9 7.0 0.4 3.4 2 1 2 4 4 4 0 Disulfide bond isomerase protein N-terminus DUF948 PF06103.11 OWF36964.1 - 0.023 14.9 17.1 0.44 10.8 2.2 3.7 1 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OWF36965.1 - 3.5e-10 40.0 4.9 0.32 11.0 0.2 5.1 1 1 7 8 8 8 7 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 OWF36965.1 - 2.6e-07 30.9 4.3 0.13 12.6 0.2 4.6 2 2 1 3 3 3 2 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 OWF36965.1 - 9.1e-07 27.9 3.0 0.0033 16.1 0.9 2.8 1 1 1 2 2 2 2 AAA domain Baculo_PEP_C PF04513.12 OWF36965.1 - 3.1e-06 27.3 0.0 0.025 14.6 0.0 3.0 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 OWF36965.1 - 0.00048 20.5 5.4 3.5 8.2 0.2 4.1 2 2 1 3 3 3 3 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 OWF36965.1 - 0.0015 18.6 0.0 26 5.0 0.0 4.4 1 1 4 6 6 6 0 Protein of unknown function (DUF2730) DUF724 PF05266.14 OWF36965.1 - 0.061 13.1 0.0 12 5.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 OWF36965.1 - 0.065 13.3 0.0 18 5.3 0.0 2.5 1 1 1 3 3 3 0 Laminin Domain II CENP-F_leu_zip PF10473.9 OWF36965.1 - 0.14 12.2 0.0 4.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCPsignal PF00015.21 OWF36965.1 - 0.3 10.9 4.8 20 4.9 0.2 3.0 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ABC_tran_CTD PF16326.5 OWF36965.1 - 7.9 6.8 7.1 17 5.8 0.4 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain GP41 PF00517.17 OWF36965.1 - 8.9 6.2 6.9 6.3e+02 0.1 6.1 3.6 1 1 1 2 2 2 0 Retroviral envelope protein Microvir_H PF04687.12 OWF36965.1 - 9.2 5.5 7.4 6.9 6.0 0.3 2.9 1 1 3 4 4 4 0 Microvirus H protein (pilot protein) LRR_8 PF13855.6 OWF36966.1 - 3.5e-22 77.9 12.0 4.8e-10 39.1 0.4 4.4 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OWF36966.1 - 2.9e-19 68.8 14.4 3.3e-06 27.3 0.1 4.6 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF36966.1 - 6.7e-09 35.1 19.0 0.069 13.2 0.0 7.2 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 OWF36966.1 - 1.3e-06 28.1 12.9 2 9.3 0.1 6.8 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 OWF36966.1 - 0.013 15.0 0.5 6.4 6.2 0.0 2.7 2 1 1 3 3 3 0 Leucine-rich repeat Ribosomal_L7Ae PF01248.26 OWF36967.1 - 1.5e-23 82.3 1.5 2.8e-23 81.5 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 OWF36967.1 - 0.0039 17.1 0.5 0.0061 16.5 0.5 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Ribonuc_red_2_N PF08471.10 OWF36968.1 - 0.016 15.4 0.0 5.4 7.3 0.0 2.1 1 1 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Bgal_small_N PF02929.17 OWF36968.1 - 0.069 12.8 1.7 0.098 12.3 1.7 1.3 1 1 0 1 1 1 0 Beta galactosidase small chain BslA PF17735.1 OWF36968.1 - 0.11 12.5 5.6 1.1 9.2 0.8 3.0 1 1 3 4 4 4 0 Biofilm surface layer A Knl1_RWD_C PF18210.1 OWF36968.1 - 0.14 12.7 6.0 0.43 11.1 3.7 2.2 1 1 1 2 2 2 0 Knl1 RWD C-terminal domain Glyco_hydro_38C PF07748.13 OWF36968.1 - 4.9 7.1 9.6 9.5 6.2 7.5 1.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain Glyco_transf_11 PF01531.16 OWF36969.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Ribosomal_S2 PF00318.20 OWF36970.1 - 3.2e-30 105.0 2.7 4.2e-15 55.6 0.3 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OWF36970.1 - 5.8e-05 24.4 8.9 0.00011 23.4 8.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus TraF PF13728.6 OWF36970.1 - 0.17 11.7 1.9 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Tfb5 PF06331.12 OWF36971.1 - 7.8e-28 96.3 0.4 8.5e-28 96.1 0.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 SERTA PF06031.13 OWF36972.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 SERTA motif Ribosomal_S3Ae PF01015.18 OWF36973.1 - 1.7e-84 282.4 4.7 2e-84 282.2 4.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Exo_endo_phos_2 PF14529.6 OWF36974.1 - 1.4e-05 25.0 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OWF36974.1 - 0.026 14.0 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF370 PF04025.12 OWF36975.1 - 0.0072 16.4 8.7 23 5.2 0.1 5.2 1 1 5 6 6 6 2 Domain of unknown function (DUF370) F-box-like PF12937.7 OWF36975.1 - 0.045 13.6 20.0 19 5.2 0.3 6.6 6 1 0 7 7 7 0 F-box-like BatA PF07584.11 OWF36975.1 - 1.2 9.5 6.3 44 4.5 0.3 4.0 1 1 2 3 3 3 0 Aerotolerance regulator N-terminal DUF4632 PF15451.6 OWF36975.1 - 9.4 6.4 29.8 15 5.8 1.0 5.2 1 1 5 6 6 6 0 Domain of unknown function (DUF4632) Ribosomal_L2_C PF03947.18 OWF36976.1 - 3.5e-47 159.7 2.7 6.2e-47 158.9 2.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OWF36976.1 - 1.2e-16 60.5 0.0 2.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Lipase_GDSL_2 PF13472.6 OWF36980.1 - 0.033 14.6 0.0 0.036 14.4 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ribosomal_L16 PF00252.18 OWF36981.1 - 2.3e-16 60.0 1.2 2.9e-16 59.7 0.1 1.6 2 1 0 2 2 2 1 Ribosomal protein L16p/L10e PGP_phosphatase PF09419.10 OWF36981.1 - 0.0062 16.2 0.1 0.0081 15.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Neur_chan_memb PF02932.16 OWF36983.1 - 4.2e-11 43.4 8.3 5.1e-11 43.1 8.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L13 PF00572.18 OWF36984.1 - 1.8e-09 37.9 0.1 3.3e-07 30.6 0.0 2.8 2 1 0 2 2 2 1 Ribosomal protein L13 Ank_5 PF13857.6 OWF36985.1 - 2.3e-05 24.5 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF36985.1 - 3.8e-05 24.2 0.0 3.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF36985.1 - 0.00015 21.9 0.0 0.0051 17.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OWF36985.1 - 0.00054 20.3 0.0 0.0025 18.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OWF36985.1 - 0.06 14.0 0.0 0.4 11.3 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF3334 PF11813.8 OWF36986.1 - 0.0039 16.9 5.8 2.9 7.6 0.2 4.0 1 1 3 4 4 4 4 Protein of unknown function (DUF3334) Ribosomal_S7 PF00177.21 OWF36987.1 - 1.1e-38 132.2 0.6 1.4e-38 131.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Colipase-like PF15083.6 OWF36988.1 - 0.11 12.6 1.0 0.35 11.0 0.6 1.6 1 1 1 2 2 2 0 Colipase-like Neur_chan_memb PF02932.16 OWF36989.1 - 2.2e-10 41.0 5.9 2.6e-10 40.8 5.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region BRI3BP PF14965.6 OWF36989.1 - 0.0067 16.0 0.9 0.0076 15.8 0.9 1.1 1 0 0 1 1 1 1 Negative regulator of p53/TP53 Bacteriocin_II PF01721.18 OWF36989.1 - 0.031 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Class II bacteriocin Botulinum_HA-17 PF05588.11 OWF36990.1 - 0.067 13.3 5.6 0.19 11.8 2.5 2.7 1 1 3 4 4 4 0 Clostridium botulinum HA-17 domain Pkinase PF00069.25 OWF36991.1 - 1.9e-12 47.1 0.0 2.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF36991.1 - 3.1e-06 26.7 0.0 3.5e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase PF01425.21 OWF36992.1 - 0.0011 18.0 0.0 0.0012 17.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Ribosomal_L13e PF01294.18 OWF36993.1 - 1.5e-64 217.2 8.5 9.3e-64 214.6 8.5 1.9 1 1 0 1 1 1 1 Ribosomal protein L13e EF-1_beta_acid PF10587.9 OWF36993.1 - 0.92 10.0 8.7 1.2 9.6 0.1 3.0 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF4097 PF13349.6 OWF36996.1 - 0.0093 15.3 3.7 0.011 15.1 3.7 1.1 1 0 0 1 1 1 1 Putative adhesin YrhK PF14145.6 OWF36996.1 - 0.23 11.4 3.1 14 5.6 3.1 2.7 1 1 0 1 1 1 0 YrhK-like protein MSG PF02349.15 OWF36996.1 - 3.4 7.9 15.0 17 5.7 6.7 2.7 1 1 1 2 2 2 0 Major surface glycoprotein Ribosomal_L18 PF17135.4 OWF36998.1 - 5.6e-95 316.1 3.7 6.2e-95 315.9 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OWF36998.1 - 0.00034 21.3 0.0 0.00034 21.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Dimerisation PF08100.11 OWF36998.1 - 0.06 13.4 0.0 17 5.6 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain zf-C2H2_4 PF13894.6 OWF36999.1 - 0.15 13.0 1.0 8.7 7.5 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF36999.1 - 0.43 11.1 3.0 2 9.1 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glyco_hydro_18 PF00704.28 OWF37000.1 - 5.4e-08 32.9 0.0 5.8e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BppL_N PF18338.1 OWF37001.1 - 0.012 15.3 0.5 1.2e+02 2.6 0.0 5.4 6 2 2 8 8 8 0 Lower baseplate protein N-terminal domain Soc PF16855.5 OWF37001.1 - 0.03 14.8 3.1 33 5.0 0.1 4.8 2 1 1 4 4 4 0 Small outer capsid protein PilX_N PF14341.6 OWF37001.1 - 0.066 13.2 15.1 0.63 10.0 0.4 5.6 3 1 1 5 5 5 0 PilX N-terminal Leptin PF02024.15 OWF37001.1 - 0.26 11.0 3.5 14 5.5 0.7 3.8 2 1 1 3 3 3 0 Leptin Thioredoxin_6 PF13848.6 OWF37002.1 - 0.11 12.4 0.9 6 6.7 0.2 2.7 1 1 2 3 3 3 0 Thioredoxin-like domain DUF4767 PF15983.5 OWF37002.1 - 0.14 12.4 1.3 4.4 7.6 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4767) UbiD PF01977.16 OWF37002.1 - 0.29 10.0 3.3 3.3 6.5 0.1 2.1 1 1 1 2 2 2 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase O_Spanin_T7 PF17531.2 OWF37002.1 - 1.3 9.1 12.0 2e+02 2.2 0.1 6.8 2 2 5 8 8 8 0 outer-membrane spanin sub-unit Pox_C7_F8A PF03287.14 OWF37002.1 - 1.4 8.9 13.7 12 5.9 1.7 4.4 1 1 3 4 4 4 0 Poxvirus C7/F8A protein DUF1919 PF08942.10 OWF37002.1 - 1.5 8.3 4.8 3.2 7.2 0.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1919) VirArc_Nuclease PF12187.8 OWF37002.1 - 3 7.4 14.5 4.2 6.9 1.5 3.7 1 1 3 4 4 4 0 Viral/Archaeal nuclease Ribosomal_L21e PF01157.18 OWF37003.1 - 1.7e-47 159.4 2.6 2.7e-47 158.8 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e PNMA PF14893.6 OWF37004.1 - 0.00067 19.2 0.0 0.0014 18.1 0.0 1.5 1 1 0 2 2 2 1 PNMA TetR_C_13 PF16925.5 OWF37004.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FAM47 PF14642.6 OWF37005.1 - 3.2e-05 23.6 0.1 0.084 12.4 0.0 2.3 1 1 1 2 2 2 2 FAM47 family Mg-por_mtran_C PF07109.11 OWF37005.1 - 7e-05 23.1 2.7 4.7 7.6 0.0 3.5 1 1 0 3 3 3 3 Magnesium-protoporphyrin IX methyltransferase C-terminus DUF1730 PF08331.10 OWF37005.1 - 0.00012 21.9 5.5 11 6.0 0.1 6.0 1 1 2 3 3 3 2 Domain of unknown function (DUF1730) A2M_BRD PF07703.14 OWF37005.1 - 0.00027 21.3 0.1 1.2 9.5 0.1 3.2 1 1 0 1 1 1 1 Alpha-2-macroglobulin bait region domain DUF4793 PF16041.5 OWF37005.1 - 0.00037 20.6 7.1 1.1 9.4 0.2 4.5 1 1 4 5 5 5 2 Domain of unknown function (DUF4793) DUF2816 PF10992.8 OWF37005.1 - 0.0018 18.1 10.3 3.4 7.6 0.6 4.2 1 1 1 3 3 3 3 Protein of unknown function (DUF2816) DUF4998 PF16389.5 OWF37005.1 - 0.0049 16.5 5.4 0.32 10.6 0.7 3.0 1 1 1 2 2 2 2 Domain of unknown function DUF3325 PF11804.8 OWF37005.1 - 0.015 15.4 0.2 1.1e+02 3.1 0.0 4.9 1 1 5 6 6 6 0 Protein of unknown function (DUF3325) RalF_SCD PF18248.1 OWF37005.1 - 0.039 13.9 0.2 4.4 7.3 0.0 2.5 1 1 1 2 2 2 0 RalF C-terminal Sec-7 capping domain PorP_SprF PF11751.8 OWF37005.1 - 0.13 11.8 2.6 1 8.8 2.5 2.0 1 1 0 1 1 1 0 Type IX secretion system membrane protein PorP/SprF RPGR1_C PF18111.1 OWF37005.1 - 0.36 10.7 2.1 11 5.9 0.4 2.8 1 1 0 2 2 2 0 Retinitis pigmentosa G-protein regulator interacting C-terminal fn3 PF00041.21 OWF37006.1 - 2.5e-12 47.0 0.0 3.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF37006.1 - 0.046 14.3 0.2 0.22 12.1 0.2 2.0 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 OWF37006.1 - 0.053 13.4 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Fibronectin-III type domain Pro_isomerase PF00160.21 OWF37007.1 - 3.8e-27 95.5 0.1 4.2e-27 95.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sec34 PF04136.15 OWF37008.1 - 0.0031 17.4 12.2 0.033 14.1 3.9 2.0 1 1 1 2 2 2 2 Sec34-like family IFT57 PF10498.9 OWF37008.1 - 0.0098 14.9 15.0 0.013 14.5 15.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Jnk-SapK_ap_N PF09744.9 OWF37008.1 - 0.011 16.0 15.6 0.033 14.4 5.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4201 PF13870.6 OWF37008.1 - 0.017 14.9 11.0 0.12 12.1 7.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 OWF37008.1 - 0.025 15.1 2.1 0.033 14.7 2.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region WXG100 PF06013.12 OWF37008.1 - 0.025 14.8 8.2 2.1 8.6 4.1 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF3552 PF12072.8 OWF37008.1 - 0.026 13.9 2.4 0.076 12.4 0.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) KELK PF15796.5 OWF37008.1 - 0.028 14.9 3.6 0.14 12.7 0.7 2.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc24 PF08286.11 OWF37008.1 - 0.055 13.7 11.1 17 5.7 11.1 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Yuri_gagarin PF15934.5 OWF37008.1 - 0.058 13.2 8.1 0.099 12.5 8.1 1.4 1 1 0 1 1 1 0 Yuri gagarin OmpH PF03938.14 OWF37008.1 - 0.059 13.7 1.4 0.087 13.2 1.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SHE3 PF17078.5 OWF37008.1 - 0.11 12.2 19.6 0.25 11.0 8.0 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.8 OWF37008.1 - 0.11 11.7 6.9 0.14 11.4 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CALCOCO1 PF07888.11 OWF37008.1 - 0.13 11.1 6.6 0.24 10.2 4.3 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Ax_dynein_light PF10211.9 OWF37008.1 - 0.18 11.7 8.2 0.95 9.4 1.8 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain BLOC1_2 PF10046.9 OWF37008.1 - 0.19 12.1 15.2 2.8 8.3 2.0 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin PF00804.25 OWF37008.1 - 0.3 10.8 11.5 0.39 10.4 11.5 1.3 1 0 0 1 1 1 0 Syntaxin EzrA PF06160.12 OWF37008.1 - 0.4 8.8 12.4 0.68 8.0 12.4 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Nup54 PF13874.6 OWF37008.1 - 0.43 10.7 9.8 2.9 8.0 9.7 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Tup_N PF08581.10 OWF37008.1 - 0.43 10.9 14.7 39 4.7 14.2 2.7 1 1 0 1 1 1 0 Tup N-terminal LPP PF04728.13 OWF37008.1 - 1.5 9.3 8.4 22 5.5 0.5 3.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper TMPIT PF07851.13 OWF37008.1 - 1.6 7.9 11.8 1.7 7.8 11.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein PTP_tm PF18861.1 OWF37008.1 - 1.6 8.7 4.8 2.1 8.3 4.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Alpha-2-MRAP_C PF06401.11 OWF37008.1 - 2.3 8.1 16.0 5.2 7.0 16.0 1.6 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF948 PF06103.11 OWF37008.1 - 2.3 8.5 10.7 6.5 7.1 1.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4472 PF14739.6 OWF37008.1 - 2.3 9.0 8.9 11 6.8 8.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Dynactin_p22 PF07426.11 OWF37008.1 - 3 7.7 14.8 2.4 8.0 3.6 2.8 1 1 2 3 3 3 0 Dynactin subunit p22 VEG PF06257.11 OWF37008.1 - 5.2 7.2 7.0 45 4.2 0.3 3.4 1 1 2 4 4 4 0 Biofilm formation stimulator VEG Malic_M PF03949.15 OWF37009.1 - 2.7e-46 158.0 0.0 3e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain BslA PF17735.1 OWF37010.1 - 0.0009 19.2 8.7 0.18 11.8 0.8 3.6 1 1 2 3 3 3 2 Biofilm surface layer A Knl1_RWD_C PF18210.1 OWF37010.1 - 0.043 14.3 7.2 0.46 11.0 3.1 2.3 1 1 1 2 2 2 0 Knl1 RWD C-terminal domain Bgal_small_N PF02929.17 OWF37010.1 - 0.51 9.9 2.2 2 8.0 2.2 1.8 1 1 0 1 1 1 0 Beta galactosidase small chain CBM_4_9 PF02018.17 OWF37010.1 - 1 9.6 10.6 0.55 10.5 1.2 2.5 1 1 1 2 2 2 0 Carbohydrate binding domain Glyco_hydro_38C PF07748.13 OWF37010.1 - 3.9 7.5 10.1 17 5.4 10.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain BslA PF17735.1 OWF37011.1 - 0.0054 16.7 4.1 1.8 8.6 0.3 3.0 1 1 3 4 4 4 3 Biofilm surface layer A Knl1_RWD_C PF18210.1 OWF37011.1 - 0.007 16.8 8.9 0.12 12.9 2.3 2.2 1 1 1 2 2 2 2 Knl1 RWD C-terminal domain Spore_YunB PF09560.10 OWF37011.1 - 0.021 14.9 3.5 0.2 11.7 0.9 2.2 1 1 2 3 3 3 0 Sporulation protein YunB (Spo_YunB) Glyco_hydro_38C PF07748.13 OWF37011.1 - 0.066 13.3 5.2 0.13 12.3 5.2 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain VIT PF08487.10 OWF37011.1 - 0.075 13.3 7.0 2.6 8.3 0.3 2.7 1 1 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Cadherin-like PF12733.7 OWF37011.1 - 0.077 13.5 0.1 1.5 9.4 0.1 2.4 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain GCV_T_C PF08669.11 OWF37011.1 - 0.12 12.3 0.0 2.4 8.1 0.0 2.0 1 1 2 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain Bgal_small_N PF02929.17 OWF37011.1 - 0.24 11.0 0.6 0.35 10.4 0.6 1.4 1 1 0 1 1 1 0 Beta galactosidase small chain AXH PF08517.12 OWF37011.1 - 0.96 10.0 5.8 2.4 8.7 1.7 2.6 1 1 1 2 2 2 0 Ataxin-1 and HBP1 module (AXH) Eaf7 PF07904.13 OWF37011.1 - 3.8 7.9 9.0 8.5e+02 0.4 9.0 3.2 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 Glyco_transf_20 PF00982.21 OWF37011.1 - 7.6 5.1 10.8 0.81 8.3 1.0 2.5 1 1 3 4 4 4 0 Glycosyltransferase family 20 Pkinase_Tyr PF07714.17 OWF37012.1 - 2e-08 33.8 0.0 2.2e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF37012.1 - 4.2e-06 26.3 0.0 4.5e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain YoeB_toxin PF06769.14 OWF37012.1 - 0.083 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Kinase-like PF14531.6 OWF37012.1 - 0.17 11.1 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF3875 PF12991.7 OWF37013.1 - 2.7e-09 36.8 1.6 7.7 6.6 0.0 6.6 1 1 7 8 8 8 6 Domain of unknown function, B. Theta Gene description (DUF3875) DUF1108 PF06531.11 OWF37013.1 - 0.81 10.0 4.2 18 5.8 0.3 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1108) GTPase_binding PF09027.10 OWF37013.1 - 6 6.9 24.0 81 3.3 1.0 6.1 1 1 2 3 3 3 0 GTPase binding Rho_N PF07498.12 OWF37014.1 - 0.012 15.5 0.6 0.019 14.9 0.6 1.3 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain SAP130_C PF16014.5 OWF37014.1 - 0.12 11.4 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Paramecium_SA PF01508.16 OWF37016.1 - 0.0061 17.0 6.7 0.046 14.2 3.0 2.5 1 1 1 2 2 2 2 Paramecium surface antigen domain zf-primase PF09329.11 OWF37016.1 - 0.22 11.3 0.0 0.22 11.3 0.0 3.9 3 1 0 3 3 3 0 Primase zinc finger RE_LlaJI PF09563.10 OWF37016.1 - 0.23 10.6 1.7 0.57 9.3 1.5 1.8 1 1 1 2 2 2 0 LlaJI restriction endonuclease TatD_DNase PF01026.21 OWF37017.1 - 3.9e-23 82.2 0.0 3.3e-18 66.0 0.1 2.0 1 1 1 2 2 2 2 TatD related DNase PTE PF02126.18 OWF37017.1 - 0.084 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family GETHR PF05671.11 OWF37018.1 - 0.0022 17.3 0.5 22 4.5 0.0 3.4 3 0 0 3 3 3 3 GETHR pentapeptide repeat (5 copies) GvpH PF05455.11 OWF37018.1 - 0.024 14.7 4.2 2.7 8.0 0.3 3.0 1 1 2 3 3 3 0 GvpH Baculo_E25 PF05274.11 OWF37018.1 - 0.16 11.8 1.1 6.7 6.5 0.2 2.7 2 1 1 3 3 3 0 Occlusion-derived virus envelope protein E25 DUF3672 PF12421.8 OWF37019.1 - 0.18 11.7 1.8 0.37 10.7 0.6 1.9 1 1 1 2 2 2 0 Fibronectin type III protein KID PF02524.14 OWF37020.1 - 2.1e-12 44.9 4.8 7.6 7.1 0.0 8.7 9 0 0 9 9 9 3 KID repeat DUF725 PF05267.12 OWF37020.1 - 0.0035 17.3 4.0 1.3 9.0 0.3 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF725) DUF1664 PF07889.12 OWF37020.1 - 0.013 15.5 0.0 0.53 10.3 0.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2630 PF10944.8 OWF37020.1 - 0.58 10.6 10.4 15 6.2 0.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2630) ESF1 PF18209.1 OWF37020.1 - 2.9 7.9 16.3 16 5.5 0.2 4.8 2 1 2 4 4 4 0 Embryo surrounding factor 1 DUF4215 PF13948.6 OWF37020.1 - 5.9 7.4 11.8 58 4.2 7.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4215) DUF5039 PF16442.5 OWF37020.1 - 8.2 5.9 6.6 49 3.4 4.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5039) Ribosomal_S8 PF00410.19 OWF37021.1 - 3.2e-23 82.1 0.1 5.3e-23 81.4 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Fz PF01392.22 OWF37022.1 - 2.7e-21 76.3 2.0 3.3e-21 76.0 2.0 1.1 1 0 0 1 1 1 1 Fz domain Ribosomal_L24e PF01246.20 OWF37023.1 - 1.1e-29 102.5 0.3 1.1e-29 102.5 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DDHD PF02862.17 OWF37023.1 - 0.35 11.0 3.3 0.4 10.8 3.3 1.1 1 0 0 1 1 1 0 DDHD domain DUF2992 PF11208.8 OWF37023.1 - 0.38 11.0 17.1 0.019 15.2 12.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) CDPS PF16715.5 OWF37023.1 - 4.5 6.9 8.5 7.1 6.2 8.5 1.4 1 1 0 1 1 1 0 Cyclodipeptide synthase Ribosomal_L23eN PF03939.13 OWF37024.1 - 5.5e-21 74.5 9.8 5.5e-21 74.5 9.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OWF37024.1 - 1.1e-13 51.3 1.1 1.1e-13 51.3 1.1 2.4 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L14 PF00238.19 OWF37025.1 - 1.1e-36 125.6 0.1 1.3e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L27A PF00828.19 OWF37026.1 - 4.9e-20 72.5 0.8 6.4e-20 72.1 0.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 OWF37026.1 - 0.19 11.8 0.3 0.3 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) DUF2627 PF11118.8 OWF37027.1 - 0.64 10.6 2.5 11 6.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Ribosomal_L28e PF01778.17 OWF37028.1 - 1.5e-29 103.0 1.9 1.5e-29 103.0 1.9 1.3 2 0 0 2 2 2 1 Ribosomal L28e protein family TTSSLRR PF12468.8 OWF37029.1 - 0.094 13.0 1.5 11 6.4 0.4 2.9 1 1 1 2 2 2 0 Type III secretion system leucine rich repeat protein Ribosomal_S10 PF00338.22 OWF37030.1 - 8.5e-29 99.7 0.5 1e-28 99.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e T3SS_needle_F PF09392.10 OWF37031.1 - 1.4 9.2 23.6 10 6.4 0.3 5.3 1 1 5 6 6 6 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF TIL PF01826.17 OWF37032.1 - 4.7e-05 23.5 2.7 7.1e-05 23.0 2.7 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain Ribosomal_L7Ae PF01248.26 OWF37033.1 - 4.1e-25 87.3 0.0 4.9e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S24e PF01282.19 OWF37034.1 - 1.7e-37 127.2 0.4 3.2e-37 126.3 0.1 1.6 1 1 1 2 2 2 1 Ribosomal protein S24e potato_inhibit PF00280.18 OWF37035.1 - 4.2e-23 81.8 1.0 4.6e-23 81.7 1.0 1.0 1 0 0 1 1 1 1 Potato inhibitor I family SSF PF00474.17 OWF37036.1 - 1.3e-05 24.3 0.3 1.6e-05 24.0 0.3 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family PHD PF00628.29 OWF37037.1 - 0.093 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 PHD-finger PIF1 PF05970.14 OWF37038.1 - 7e-07 28.7 0.1 7.5e-07 28.6 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 OWF37038.1 - 0.00036 20.9 0.1 0.00039 20.8 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OWF37038.1 - 0.0055 16.4 0.0 0.006 16.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OWF37038.1 - 0.072 13.0 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 NTPase Ribosomal_L29 PF00831.23 OWF37039.1 - 8.6e-17 60.9 1.8 8.6e-17 60.9 1.8 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein Transcrip_act PF04949.13 OWF37039.1 - 0.0087 16.0 1.4 0.0087 16.0 1.4 2.2 1 1 1 2 2 2 1 Transcriptional activator FlxA PF14282.6 OWF37039.1 - 0.03 14.3 2.7 0.056 13.4 2.7 1.4 1 0 0 1 1 1 0 FlxA-like protein Methyltransf_32 PF13679.6 OWF37039.1 - 0.14 12.1 1.4 0.12 12.4 0.3 1.4 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_S25 PF03297.15 OWF37040.1 - 1.7e-44 150.2 4.7 1.9e-44 150.0 4.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 OWF37040.1 - 0.0002 20.9 0.2 0.00031 20.3 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 OWF37040.1 - 0.00037 20.3 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 MarR family MarR PF01047.22 OWF37040.1 - 0.00082 19.2 0.1 0.0012 18.7 0.1 1.2 1 0 0 1 1 1 1 MarR family DUF3516 PF12029.8 OWF37040.1 - 0.003 16.7 0.6 0.003 16.7 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) EAP30 PF04157.16 OWF37040.1 - 0.0069 15.7 0.0 0.0074 15.6 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family GntR PF00392.21 OWF37040.1 - 0.0075 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family RNA_pol_Rpc34 PF05158.12 OWF37040.1 - 0.016 14.6 0.4 0.017 14.5 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit TrmB PF01978.19 OWF37040.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 OWF37040.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein Ribosomal_L31e PF01198.19 OWF37041.1 - 1.6e-40 137.2 1.9 2e-40 136.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 OWF37041.1 - 0.0029 17.6 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Ribosomal_L44 PF00935.19 OWF37044.1 - 1.5e-36 124.7 11.2 2.8e-36 123.8 11.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 OWF37044.1 - 0.057 13.7 1.0 0.11 12.9 1.0 1.4 1 0 0 1 1 1 0 Cathelicidin Ribosomal_L22e PF01776.17 OWF37045.1 - 3.5e-43 146.4 0.6 3.9e-43 146.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Ribosomal_L28 PF00830.19 OWF37045.1 - 0.095 12.9 1.6 0.14 12.4 1.6 1.3 1 0 0 1 1 1 0 Ribosomal L28 family Ribosomal_L37e PF01907.19 OWF37046.1 - 2e-25 88.7 12.2 3.8e-25 87.8 12.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 OWF37046.1 - 0.0015 18.5 1.4 0.0024 17.9 1.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 OWF37046.1 - 0.017 15.2 0.4 0.019 15.0 0.4 1.2 1 0 0 1 1 1 0 SelR domain zf-NADH-PPase PF09297.11 OWF37046.1 - 0.12 12.1 8.6 1.7 8.4 7.9 2.2 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_S27 PF01599.19 OWF37046.1 - 0.13 12.4 6.6 0.28 11.4 6.6 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a HypA PF01155.19 OWF37046.1 - 0.13 12.3 1.4 0.18 11.8 1.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 OWF37046.1 - 0.32 10.8 7.0 2.3 8.1 0.3 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OWF37046.1 - 0.53 9.8 5.6 1.5 8.4 5.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OWF37046.1 - 0.77 9.9 4.7 2.9 8.1 0.3 2.2 1 1 1 2 2 2 0 Zinc ribbon domain DUF2256 PF10013.9 OWF37046.1 - 1.2 9.3 6.2 3.3 7.9 0.4 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TF_Zn_Ribbon PF08271.12 OWF37046.1 - 3.3 7.3 5.4 2.5 7.7 0.4 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding Ribosomal_S27e PF01667.17 OWF37047.1 - 5.4e-28 96.5 1.6 6.5e-28 96.2 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_6 PF14599.6 OWF37047.1 - 0.01 15.8 0.9 0.015 15.3 0.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon ArfGap PF01412.18 OWF37047.1 - 0.022 14.8 0.2 0.027 14.5 0.2 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Hormone_6 PF00236.18 OWF37047.1 - 0.044 13.8 0.5 0.059 13.4 0.5 1.3 1 0 0 1 1 1 0 Glycoprotein hormone TF_Zn_Ribbon PF08271.12 OWF37047.1 - 0.071 12.6 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Ribosomal_L37ae PF01780.19 OWF37048.1 - 6.7e-42 141.5 8.9 7.5e-42 141.3 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 OWF37048.1 - 6.7e-05 22.8 3.3 0.00013 21.9 3.3 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.13 OWF37048.1 - 0.02 15.0 0.7 0.03 14.4 0.7 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 OWF37048.1 - 0.028 14.8 0.2 0.047 14.1 0.2 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.10 OWF37048.1 - 0.034 13.9 2.5 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Di19 PF05605.12 OWF37048.1 - 0.066 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 OWF37048.1 - 0.23 11.9 8.0 0.33 11.4 1.1 2.6 2 1 1 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 OWF37048.1 - 0.56 10.3 6.2 1.1 9.3 0.3 2.5 2 1 1 3 3 3 0 BED zinc finger potato_inhibit PF00280.18 OWF37050.1 - 1.2e-19 70.7 1.5 1.3e-19 70.6 1.5 1.0 1 0 0 1 1 1 1 Potato inhibitor I family potato_inhibit PF00280.18 OWF37051.1 - 1.6e-21 76.7 0.1 1.9e-21 76.5 0.1 1.0 1 0 0 1 1 1 1 Potato inhibitor I family C1q PF00386.21 OWF37052.1 - 1.5e-05 25.2 0.0 1.5e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 C1q domain SH3_9 PF14604.6 OWF37052.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain potato_inhibit PF00280.18 OWF37053.1 - 7.1e-23 81.1 1.5 7.8e-23 80.9 1.5 1.0 1 0 0 1 1 1 1 Potato inhibitor I family Ribosomal_L38e PF01781.18 OWF37054.1 - 2.9e-34 117.0 7.6 3.2e-34 116.9 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Pox_A3L PF05288.11 OWF37054.1 - 0.023 14.7 1.1 2.2 8.4 0.1 2.1 1 1 1 2 2 2 0 Poxvirus A3L Protein TFIID_NTD2 PF04494.15 OWF37054.1 - 0.041 14.1 0.5 0.049 13.9 0.5 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain PUF PF00806.19 OWF37055.1 - 0.069 12.9 3.9 15 5.5 0.2 3.8 1 1 5 6 6 6 0 Pumilio-family RNA binding repeat Ribosomal_S30 PF04758.14 OWF37056.1 - 2.3e-27 95.0 9.4 2.5e-27 94.8 9.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 EF-hand_1 PF00036.32 OWF37057.1 - 3.8e-26 88.7 7.9 1.8e-08 33.3 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37057.1 - 1.3e-24 86.4 4.6 2.7e-14 53.4 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37057.1 - 7.5e-24 83.3 8.4 5.2e-09 35.8 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37057.1 - 2.1e-21 74.0 5.3 3.8e-08 32.6 0.2 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF37057.1 - 5.2e-13 47.8 5.6 6.2e-05 22.3 0.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OWF37057.1 - 3.1e-10 40.2 0.2 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37057.1 - 7.6e-05 23.0 0.3 0.03 14.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 OWF37057.1 - 0.00033 20.7 1.2 0.001 19.1 0.3 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF4497 PF14924.6 OWF37057.1 - 0.0011 19.5 0.1 0.49 10.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4497) EF-hand_4 PF12763.7 OWF37057.1 - 0.01 15.8 3.2 3.3 7.7 0.7 2.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF37057.1 - 0.014 15.5 0.1 0.15 12.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF4304 PF14137.6 OWF37057.1 - 0.019 15.1 0.1 0.3 11.3 0.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) FGAR-AT_linker PF18072.1 OWF37057.1 - 0.026 15.1 0.2 3.1 8.4 0.1 2.8 3 1 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain RNA_pol_Rpb4 PF03874.16 OWF37057.1 - 0.029 14.7 4.5 1.5 9.1 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 EF-hand_11 PF08976.11 OWF37057.1 - 0.041 14.8 0.1 3.3 8.6 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain SapB_1 PF05184.15 OWF37057.1 - 0.052 13.6 5.8 6.2 6.9 0.0 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 Acetyltransf_11 PF13720.6 OWF37057.1 - 0.06 13.8 0.1 1 9.9 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Caleosin PF05042.13 OWF37057.1 - 0.19 11.7 1.7 22 4.9 0.1 3.0 1 1 2 3 3 3 0 Caleosin related protein DUF2757 PF10955.8 OWF37057.1 - 0.28 11.5 1.8 1.2 9.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) Glycos_trans_3N PF02885.17 OWF37057.1 - 7.2 6.5 6.1 15 5.5 0.2 3.4 2 1 0 3 3 3 0 Glycosyl transferase family, helical bundle domain EF-hand_1 PF00036.32 OWF37058.1 - 2.6e-41 136.1 14.0 1.1e-09 37.2 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37058.1 - 9.4e-37 125.3 3.3 9.1e-19 67.7 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37058.1 - 3.8e-32 109.9 14.5 1.7e-11 43.8 1.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37058.1 - 1.2e-30 102.8 7.4 1.1e-08 34.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37058.1 - 1.9e-25 87.2 11.6 7.9e-07 28.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37058.1 - 6.4e-17 61.6 0.1 3.2e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37058.1 - 1.3e-08 34.8 1.2 0.00031 20.7 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37058.1 - 1.4e-07 31.8 0.1 0.016 15.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF37058.1 - 2.4e-05 25.1 0.0 0.013 16.4 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 OWF37058.1 - 3.1e-05 23.9 0.6 0.13 12.3 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF37058.1 - 0.00013 22.1 1.5 0.29 11.3 1.5 2.8 1 1 0 1 1 1 1 Dockerin type I domain DUF4497 PF14924.6 OWF37058.1 - 0.00028 21.3 0.0 0.043 14.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) YqeY PF09424.10 OWF37058.1 - 0.00035 20.7 1.2 0.007 16.5 0.3 2.2 1 1 1 2 2 2 1 Yqey-like protein DUF1103 PF06513.11 OWF37058.1 - 0.00042 20.0 2.4 0.00052 19.7 2.4 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 OWF37058.1 - 0.0031 18.3 0.3 4 8.3 0.0 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF5580 PF17743.1 OWF37058.1 - 0.0034 16.0 0.0 0.0037 15.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 OWF37058.1 - 0.0058 17.0 0.1 0.073 13.4 0.1 2.4 1 1 0 1 1 1 1 EF-hand domain EFhand_Ca_insen PF08726.10 OWF37058.1 - 0.0062 16.6 0.1 0.017 15.2 0.0 1.9 2 0 0 2 2 1 1 Ca2+ insensitive EF hand Pyr_redox_2 PF07992.14 OWF37058.1 - 0.0074 15.5 0.5 0.45 9.7 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TerB PF05099.13 OWF37058.1 - 0.0091 16.0 0.6 0.14 12.2 0.1 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.13 OWF37058.1 - 0.015 15.3 2.1 3.4 7.6 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 OWF37058.1 - 0.016 15.5 2.8 2.6 8.4 0.3 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 dCache_2 PF08269.11 OWF37058.1 - 0.024 13.8 0.1 7.1 5.7 0.0 2.5 1 1 1 2 2 2 0 Cache domain FlgD PF03963.14 OWF37058.1 - 0.042 14.1 0.2 0.47 10.8 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF5547 PF17701.1 OWF37058.1 - 0.054 13.4 0.1 6.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5547) Phage_TAC_12 PF12363.8 OWF37058.1 - 0.081 13.3 1.1 4.1 7.8 0.2 2.4 2 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC FGAR-AT_linker PF18072.1 OWF37058.1 - 0.091 13.3 0.0 0.89 10.1 0.0 2.4 2 2 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF1296 PF06972.11 OWF37058.1 - 0.094 12.9 3.6 5.3 7.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1296) PMBR PF09373.10 OWF37058.1 - 0.11 12.7 0.0 58 4.1 0.0 3.4 3 0 0 3 3 3 0 Pseudomurein-binding repeat PB1 PF00564.24 OWF37058.1 - 0.16 11.9 6.0 16 5.5 0.3 3.7 2 2 1 3 3 3 0 PB1 domain EF-hand_1 PF00036.32 OWF37059.1 - 2.2e-32 108.2 10.0 3.7e-08 32.4 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37059.1 - 3.2e-26 91.6 2.1 2.6e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37059.1 - 1.1e-22 77.9 5.6 2.5e-07 30.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37059.1 - 1.3e-20 73.0 9.8 2.3e-09 36.9 0.1 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF37059.1 - 3.1e-15 54.9 7.1 1.4e-06 27.6 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OWF37059.1 - 9.2e-14 51.5 0.4 5.8e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37059.1 - 1.1e-06 28.5 3.9 0.0029 17.5 0.7 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37059.1 - 2.9e-06 27.6 0.4 0.0032 17.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OWF37059.1 - 0.0052 16.7 0.9 1.2 9.0 0.0 3.2 1 1 3 4 4 4 1 Caleosin related protein GPHH PF16905.5 OWF37059.1 - 0.015 15.1 0.0 0.75 9.6 0.0 2.9 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated dCache_2 PF08269.11 OWF37059.1 - 0.033 13.4 0.0 3.1 6.9 0.0 2.1 1 1 1 2 2 2 0 Cache domain TerB PF05099.13 OWF37059.1 - 0.034 14.1 1.0 1.6 8.7 0.0 2.6 1 1 2 3 3 3 0 Tellurite resistance protein TerB DUF5644 PF18712.1 OWF37059.1 - 0.094 12.7 0.3 1.2 9.2 0.1 2.3 1 1 2 3 3 3 0 Family of unknown function (DUF5644) FGAR-AT_linker PF18072.1 OWF37059.1 - 0.095 13.3 0.0 0.8 10.3 0.0 2.4 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain LTD PF00932.19 OWF37059.1 - 0.17 12.3 0.6 0.43 10.9 0.1 1.9 3 0 0 3 3 2 0 Lamin Tail Domain RloB PF13707.6 OWF37059.1 - 0.18 12.0 0.8 0.26 11.4 0.4 1.6 1 1 1 2 2 2 0 RloB-like protein Tsc35 PF15079.6 OWF37059.1 - 4.2 6.9 9.6 6.6 6.3 1.8 3.1 1 1 3 4 4 4 0 Testis-specific protein 35 EF-hand_1 PF00036.32 OWF37060.1 - 9e-35 115.6 15.0 1.1e-08 34.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37060.1 - 2.5e-32 111.1 5.6 1.3e-15 57.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37060.1 - 2.3e-29 101.0 12.0 1.6e-13 50.3 1.0 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37060.1 - 1.3e-28 96.4 8.0 9e-08 31.5 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37060.1 - 2.2e-18 64.8 16.9 3.4e-07 29.4 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 OWF37060.1 - 7.4e-15 55.0 0.5 5.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37060.1 - 4.2e-11 42.7 0.3 2.8e-05 24.0 0.1 2.1 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37060.1 - 1.5e-06 28.5 0.1 0.02 15.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 OWF37060.1 - 8e-05 22.6 0.1 0.37 10.8 0.2 2.3 2 0 0 2 2 2 2 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.10 OWF37060.1 - 0.00012 22.1 0.2 0.0005 20.1 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 OWF37060.1 - 0.00014 22.7 0.0 0.065 14.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 OWF37060.1 - 0.0026 16.4 0.0 0.35 9.3 0.0 1.9 1 1 1 2 2 2 2 Family of unknown function (DUF5580) Sen15 PF09631.10 OWF37060.1 - 0.056 13.7 0.0 0.45 10.8 0.0 2.0 1 1 1 2 2 2 0 Sen15 protein RNA_pol_Rpb4 PF03874.16 OWF37060.1 - 0.06 13.7 3.9 5.6 7.3 0.2 2.7 3 1 0 3 3 2 0 RNA polymerase Rpb4 PMBR PF09373.10 OWF37060.1 - 0.065 13.4 0.0 6.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat Beta-lactamase2 PF13354.6 OWF37060.1 - 0.093 12.3 0.0 3.1 7.3 0.0 2.1 1 1 0 2 2 2 0 Beta-lactamase enzyme family Caleosin PF05042.13 OWF37060.1 - 0.097 12.6 1.1 13 5.7 0.0 3.2 1 1 1 2 2 2 0 Caleosin related protein EF-hand_1 PF00036.32 OWF37061.1 - 8.6e-27 90.7 14.2 2.5e-08 32.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37061.1 - 4.1e-26 91.2 5.8 1.6e-12 47.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37061.1 - 2e-20 70.9 9.9 5.5e-07 29.0 0.0 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OWF37061.1 - 3.3e-20 71.7 12.8 9e-09 35.1 0.7 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF37061.1 - 1.5e-18 65.4 9.7 1.3e-05 24.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37061.1 - 1.4e-12 47.8 0.7 2.2e-08 34.3 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37061.1 - 5e-06 26.4 6.9 0.035 14.1 1.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OWF37061.1 - 0.00014 21.9 5.5 2.4 8.4 0.0 3.1 2 1 0 3 3 3 3 Dockerin type I domain OsmC PF02566.19 OWF37061.1 - 0.0034 17.8 0.1 0.017 15.6 0.1 1.9 2 0 0 2 2 2 1 OsmC-like protein ASL_C PF08328.11 OWF37061.1 - 0.096 12.8 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminal EF-hand_11 PF08976.11 OWF37061.1 - 0.099 13.5 0.1 0.97 10.3 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 OWF37062.1 - 8.6e-17 59.4 6.2 2.8e-07 29.6 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF37062.1 - 1.2e-16 60.9 4.5 3.8e-14 52.9 1.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37062.1 - 1.4e-16 60.1 2.7 7.7e-10 38.5 0.4 3.8 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37062.1 - 8.6e-15 53.3 5.4 2.7e-07 30.0 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OWF37062.1 - 2.7e-13 48.7 8.2 1.5e-06 27.4 0.1 3.6 3 1 1 4 4 4 2 EF hand EF-hand_4 PF12763.7 OWF37062.1 - 2.8e-07 30.4 1.0 6.7e-06 26.0 0.2 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF37062.1 - 7.4e-05 23.0 0.2 0.06 13.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37062.1 - 0.00015 22.1 0.6 0.00051 20.3 0.6 1.9 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF3944 PF13099.6 OWF37062.1 - 0.11 12.4 1.3 6.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) EF-hand_1 PF00036.32 OWF37063.1 - 8.4e-30 100.1 16.4 1.4e-08 33.7 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37063.1 - 3.4e-28 97.9 5.8 1.2e-16 60.9 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37063.1 - 1.3e-23 82.6 15.7 8.9e-15 54.3 2.9 3.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37063.1 - 4.3e-22 76.1 9.2 1.1e-06 28.1 0.3 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37063.1 - 9.4e-20 69.2 10.5 2.1e-06 27.0 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37063.1 - 1.5e-16 60.4 0.1 1.7e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37063.1 - 7.4e-06 26.3 0.7 0.017 15.5 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OWF37063.1 - 9.1e-06 25.7 0.4 0.11 12.4 0.0 2.9 2 2 0 2 2 2 2 Caleosin related protein UPF0154 PF03672.13 OWF37063.1 - 5.8e-05 23.0 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 OWF37063.1 - 0.00021 21.2 3.3 0.23 11.5 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 OWF37063.1 - 0.001 19.3 0.5 0.011 16.0 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain DUF1296 PF06972.11 OWF37063.1 - 0.0043 17.2 0.7 4.1 7.6 0.1 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1296) GPHH PF16905.5 OWF37063.1 - 0.075 12.8 0.0 3.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated DUF1456 PF07308.13 OWF37063.1 - 0.19 12.1 1.1 14 6.1 0.0 2.6 3 1 0 3 3 2 0 Protein of unknown function (DUF1456) Dockerin_1 PF00404.18 OWF37063.1 - 0.23 11.7 2.8 2.6 8.3 0.2 2.9 1 1 3 4 4 4 0 Dockerin type I domain EF-hand_1 PF00036.32 OWF37064.1 - 3.7e-31 104.3 15.7 2.9e-08 32.7 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37064.1 - 4.2e-29 100.8 2.9 7.3e-14 52.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37064.1 - 1.4e-26 90.1 5.8 1.4e-07 30.9 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37064.1 - 1.9e-23 82.1 9.2 5.6e-12 45.3 0.4 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF37064.1 - 2e-20 71.3 6.9 1.2e-05 24.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37064.1 - 1.4e-15 57.4 0.0 4.9e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37064.1 - 3.2e-07 30.6 0.0 0.0022 18.3 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF37064.1 - 8.6e-05 22.4 0.2 0.26 11.2 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF37064.1 - 0.0031 17.5 2.1 0.46 10.5 0.0 2.5 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 OWF37064.1 - 0.014 15.4 1.7 8.3 6.3 0.0 3.7 1 1 3 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 OWF37064.1 - 0.022 15.0 0.3 1.2 9.4 0.1 3.1 3 1 1 4 4 4 0 Dockerin type I domain DUF3349 PF11829.8 OWF37064.1 - 0.091 13.6 0.0 1.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_7 PF13499.6 OWF37065.1 - 1.3e-13 51.2 0.2 5.5e-09 36.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37065.1 - 9.3e-12 43.9 0.3 0.00014 21.5 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OWF37065.1 - 9.6e-11 40.4 1.8 0.0023 17.4 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF37065.1 - 0.00012 21.9 0.0 0.28 11.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF37065.1 - 0.0024 17.3 1.2 0.039 13.5 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 OWF37066.1 - 7.9e-33 109.6 12.7 9.9e-09 34.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37066.1 - 8.7e-27 93.4 4.2 1.4e-13 51.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37066.1 - 9e-25 84.5 6.2 3.6e-08 32.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF37066.1 - 1.8e-21 74.6 6.9 2.1e-06 27.0 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF37066.1 - 4e-19 68.2 12.1 9.9e-10 38.1 0.3 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF37066.1 - 6.3e-10 39.2 0.3 1.2e-05 25.5 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37066.1 - 8.9e-09 35.2 0.6 0.001 19.0 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OWF37066.1 - 4.4e-05 23.6 8.6 0.088 13.0 0.6 3.1 2 2 1 3 3 3 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OWF37066.1 - 9.8e-05 22.6 0.2 0.3 11.4 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF37066.1 - 0.0049 16.9 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 2 1 Uncharacterised protein family (UPF0154) Nse4-Nse3_bdg PF15412.6 OWF37066.1 - 0.042 14.0 1.1 0.09 12.9 1.1 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE RNA_pol_Rpb4 PF03874.16 OWF37066.1 - 0.048 14.0 0.3 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF4497 PF14924.6 OWF37066.1 - 0.05 14.1 0.0 0.21 12.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) EF-hand_7 PF13499.6 OWF37067.1 - 1.9e-27 95.5 7.6 6.2e-17 61.8 2.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF37067.1 - 1.5e-26 89.9 13.9 1.2e-09 37.0 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF37067.1 - 2e-22 77.1 8.7 1.8e-09 36.8 0.1 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OWF37067.1 - 1.9e-17 62.8 13.2 1.9e-09 37.3 2.4 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF37067.1 - 1.4e-15 55.9 3.0 1.1e-06 27.8 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OWF37067.1 - 3.9e-10 39.9 1.3 2.6e-07 30.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37067.1 - 1.6e-06 28.0 5.0 0.051 13.5 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF37067.1 - 0.0018 18.2 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 OWF37067.1 - 0.0022 18.3 3.5 0.48 10.8 0.7 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 OWF37067.1 - 0.0075 16.3 1.0 1.2 9.3 0.2 2.6 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 OWF37067.1 - 0.013 15.4 0.1 4.1 7.3 0.0 2.6 2 1 0 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 OWF37067.1 - 0.015 16.2 0.2 0.057 14.3 0.1 1.8 1 1 1 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 OWF37067.1 - 0.063 13.6 0.3 0.35 11.3 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain Toprim_2 PF13155.6 OWF37067.1 - 0.069 13.6 0.5 2.1 8.8 0.0 2.6 2 1 0 2 2 2 0 Toprim-like SurA_N_3 PF13624.6 OWF37067.1 - 0.14 12.0 0.2 0.85 9.4 0.1 2.0 2 0 0 2 2 2 0 SurA N-terminal domain Dockerin_1 PF00404.18 OWF37067.1 - 0.15 12.3 0.8 1.2 9.4 0.2 2.6 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_1 PF00036.32 OWF37068.1 - 1.1e-36 121.6 20.3 5e-10 38.2 1.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37068.1 - 4.7e-31 107.1 12.7 1.7e-15 57.2 4.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37068.1 - 1.3e-28 96.5 12.4 6.9e-10 38.1 0.4 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37068.1 - 2.9e-26 89.7 17.4 1.1e-08 34.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF37068.1 - 1.8e-25 88.6 15.2 1.7e-14 53.4 2.1 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF37068.1 - 1.2e-10 41.6 2.2 6.9e-06 26.3 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37068.1 - 2.8e-10 40.5 3.6 9.6e-05 22.7 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF37068.1 - 6.8e-08 33.3 1.5 0.001 19.9 0.3 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OWF37068.1 - 1.2e-06 28.6 7.2 0.087 13.0 1.3 3.8 1 1 2 3 3 3 3 Dockerin type I domain EF-hand_4 PF12763.7 OWF37068.1 - 6.6e-06 26.0 7.0 0.026 14.5 1.7 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 OWF37068.1 - 0.00014 21.6 2.1 0.021 14.6 0.3 2.1 1 1 1 2 2 2 2 SurA N-terminal domain UPF0154 PF03672.13 OWF37068.1 - 0.00019 21.4 0.2 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF2666 PF10869.8 OWF37068.1 - 0.00038 20.7 2.1 0.033 14.4 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2666) SurA_N_2 PF13623.6 OWF37068.1 - 0.00047 20.0 3.0 0.046 13.6 0.7 2.2 1 1 1 2 2 2 2 SurA N-terminal domain LXG PF04740.12 OWF37068.1 - 0.00072 19.3 2.2 0.29 10.8 0.1 2.4 1 1 0 2 2 2 2 LXG domain of WXG superfamily Caleosin PF05042.13 OWF37068.1 - 0.0072 16.3 0.4 0.82 9.6 0.0 2.7 1 1 2 3 3 3 1 Caleosin related protein DUF533 PF04391.12 OWF37068.1 - 0.03 13.9 3.0 1.8 8.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF533) GlutR_dimer PF00745.20 OWF37068.1 - 0.058 13.9 0.5 11 6.6 0.0 2.1 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF1811 PF08838.10 OWF37068.1 - 0.059 13.6 0.2 6.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) DUF3349 PF11829.8 OWF37068.1 - 0.065 14.0 1.7 11 6.9 0.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Adenine_glyco PF03352.13 OWF37068.1 - 0.079 12.7 1.3 3.4 7.4 0.1 2.1 1 1 0 2 2 2 0 Methyladenine glycosylase DUF2267 PF10025.9 OWF37068.1 - 0.084 13.1 0.2 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DnaG_DnaB_bind PF08278.11 OWF37068.1 - 0.2 12.3 2.4 5 7.8 0.7 2.8 1 1 0 2 2 2 0 DNA primase DnaG DnaB-binding RNA_pol_Rpb4 PF03874.16 OWF37068.1 - 0.21 11.9 5.1 5.2 7.4 0.3 2.7 1 1 1 2 2 2 0 RNA polymerase Rpb4 EF-hand_14 PF17959.1 OWF37068.1 - 0.51 10.7 3.6 13 6.2 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 OWF37069.1 - 7e-37 122.2 7.6 2.1e-09 36.3 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37069.1 - 2.5e-31 107.9 0.9 9.1e-16 58.1 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37069.1 - 1.8e-30 102.2 5.8 7.3e-10 38.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37069.1 - 1.8e-27 93.6 7.2 2.8e-07 29.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF37069.1 - 2.6e-25 88.0 8.8 2.5e-12 46.5 0.5 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF37069.1 - 1.4e-09 38.2 0.1 3.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37069.1 - 7.2e-09 36.0 0.0 9.2e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF37069.1 - 3.8e-08 33.2 0.1 0.0014 18.5 0.0 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OWF37069.1 - 4.3e-05 23.6 3.5 0.22 11.8 0.4 3.2 1 1 2 3 3 3 3 Dockerin type I domain SurA_N_3 PF13624.6 OWF37069.1 - 0.00032 20.5 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 2 SurA N-terminal domain EFhand_Ca_insen PF08726.10 OWF37069.1 - 0.0025 17.9 0.1 0.0071 16.4 0.1 1.8 1 1 0 1 1 1 1 Ca2+ insensitive EF hand MotA_activ PF09114.10 OWF37069.1 - 0.0031 17.6 0.6 0.065 13.4 0.1 2.2 1 1 0 2 2 2 1 Transcription factor MotA, activation domain EF-hand_11 PF08976.11 OWF37069.1 - 0.0034 18.2 0.0 0.05 14.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain DUF3349 PF11829.8 OWF37069.1 - 0.004 17.9 0.0 2 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) TerB PF05099.13 OWF37069.1 - 0.0064 16.5 0.0 0.53 10.2 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.13 OWF37069.1 - 0.0077 16.2 0.3 0.74 9.7 0.0 3.0 2 2 2 4 4 4 1 Caleosin related protein UPF0154 PF03672.13 OWF37069.1 - 0.01 15.8 0.0 6.5 6.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) SurA_N_2 PF13623.6 OWF37069.1 - 0.013 15.4 0.5 0.095 12.6 0.3 2.0 1 1 1 2 2 2 0 SurA N-terminal domain DUF5547 PF17701.1 OWF37069.1 - 0.057 13.3 0.2 4.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5547) RloB PF13707.6 OWF37069.1 - 0.16 12.2 0.1 0.48 10.6 0.1 1.8 1 1 0 1 1 1 0 RloB-like protein EF-hand_1 PF00036.32 OWF37070.1 - 4.6e-62 201.0 28.5 2.1e-09 36.2 0.0 8.1 8 0 0 8 8 8 8 EF hand EF-hand_7 PF13499.6 OWF37070.1 - 2.1e-59 197.9 12.6 6.6e-15 55.3 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 OWF37070.1 - 2e-49 165.2 29.1 1.1e-12 47.5 0.1 7.9 3 3 5 8 8 8 8 EF-hand domain pair EF-hand_6 PF13405.6 OWF37070.1 - 4.4e-45 147.8 20.8 3.6e-09 35.8 0.1 8.2 8 0 0 8 8 8 6 EF-hand domain EF-hand_5 PF13202.6 OWF37070.1 - 7.1e-38 126.5 23.9 2e-06 27.0 0.0 8.1 8 0 0 8 8 8 7 EF hand EF-hand_9 PF14658.6 OWF37070.1 - 4.1e-27 94.3 2.8 1e-08 35.4 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37070.1 - 4.1e-12 46.4 0.1 0.11 12.8 0.0 4.1 1 1 3 4 4 4 4 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF37070.1 - 1e-11 45.6 0.0 0.11 13.3 0.0 4.0 1 1 3 4 4 4 3 EF-hand domain UPF0154 PF03672.13 OWF37070.1 - 1.4e-09 37.9 0.0 0.12 12.4 0.0 5.1 4 1 1 5 5 5 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF37070.1 - 7.2e-09 35.7 16.0 0.0081 16.3 0.1 5.2 3 1 2 5 5 5 3 Dockerin type I domain EF-hand_4 PF12763.7 OWF37070.1 - 8.8e-09 35.3 5.2 0.15 12.0 0.1 4.6 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF37070.1 - 1.1e-07 32.0 3.6 0.8 9.6 0.0 5.7 2 2 4 6 6 6 2 Caleosin related protein EF-hand_14 PF17959.1 OWF37070.1 - 6.5e-05 23.2 2.3 5.4 7.4 0.0 4.3 3 1 1 4 4 4 0 EF-hand domain Amdo_NSP PF12475.8 OWF37070.1 - 0.00063 19.8 0.0 3.9 7.6 0.0 3.2 3 0 0 3 3 3 1 Amdovirus non-structural protein EFhand_Ca_insen PF08726.10 OWF37070.1 - 0.00071 19.6 0.5 0.0098 16.0 0.0 2.9 3 1 0 3 3 2 1 Ca2+ insensitive EF hand MotA_activ PF09114.10 OWF37070.1 - 0.0009 19.3 0.1 1.3 9.2 0.0 3.4 3 0 0 3 3 3 1 Transcription factor MotA, activation domain SurA_N_2 PF13623.6 OWF37070.1 - 0.0035 17.2 2.6 6.1 6.7 0.1 4.0 1 1 3 4 4 4 0 SurA N-terminal domain DUF4497 PF14924.6 OWF37070.1 - 0.0055 17.2 0.0 2.1 8.9 0.0 3.3 4 0 0 4 4 3 1 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 OWF37070.1 - 0.0066 16.8 5.7 3.8 7.9 0.1 4.2 5 0 0 5 5 4 1 RNA polymerase Rpb4 dCache_2 PF08269.11 OWF37070.1 - 0.0099 15.1 0.3 0.51 9.5 0.1 3.0 2 1 1 3 3 3 1 Cache domain DUF1103 PF06513.11 OWF37070.1 - 0.013 15.1 2.1 0.013 15.1 2.1 2.2 2 1 0 2 2 2 0 Repeat of unknown function (DUF1103) FGAR-AT_linker PF18072.1 OWF37070.1 - 0.014 16.0 0.7 42 4.8 0.0 4.0 4 0 0 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain DED PF01335.21 OWF37070.1 - 0.016 15.5 1.4 6.4 7.2 0.1 2.9 3 0 0 3 3 2 0 Death effector domain Poly_export PF02563.16 OWF37070.1 - 0.02 15.1 0.1 0.7 10.2 0.0 3.3 3 1 0 3 3 3 0 Polysaccharide biosynthesis/export protein ICAT PF06384.11 OWF37070.1 - 0.023 15.0 0.1 0.2 11.9 0.0 2.3 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT GPHH PF16905.5 OWF37070.1 - 0.05 13.4 0.0 30 4.5 0.0 4.2 5 0 0 5 5 5 0 Voltage-dependent L-type calcium channel, IQ-associated UBA_6 PF18039.1 OWF37070.1 - 0.055 13.4 0.2 59 3.7 0.0 3.5 4 0 0 4 4 3 0 UBA-like domain TerB PF05099.13 OWF37070.1 - 0.062 13.3 0.4 1.6 8.7 0.0 3.0 2 2 3 5 5 5 0 Tellurite resistance protein TerB PHY PF00360.20 OWF37070.1 - 0.12 11.7 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Phytochrome region Cas_Csa5 PF09702.10 OWF37070.1 - 0.15 12.3 0.1 7.6 6.8 0.0 2.9 3 1 0 3 3 3 0 CRISPR-associated protein (Cas_Csa5) SapB_1 PF05184.15 OWF37070.1 - 0.2 11.7 3.0 8.8 6.5 0.1 3.5 5 0 0 5 5 4 0 Saposin-like type B, region 1 L27_N PF09060.10 OWF37070.1 - 0.23 11.6 0.8 6.9 6.8 0.0 2.9 3 0 0 3 3 3 0 L27_N Spore_III_AB PF09548.10 OWF37070.1 - 0.38 10.8 1.4 1.2 9.2 0.1 2.1 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RloB PF13707.6 OWF37070.1 - 0.85 9.8 3.8 1.6 8.9 0.3 2.9 2 1 1 3 3 3 0 RloB-like protein DUF5132 PF17195.4 OWF37070.1 - 1.1 9.5 3.6 59 3.9 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF5132) EF-hand_1 PF00036.32 OWF37071.1 - 3.4e-31 104.5 8.9 4.2e-07 29.1 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37071.1 - 2.1e-30 105.0 3.3 1.7e-14 54.0 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37071.1 - 1.1e-24 86.0 9.7 1.8e-11 43.7 1.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37071.1 - 1.7e-24 83.6 4.0 7.5e-07 28.6 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37071.1 - 1.2e-19 68.8 8.5 2.9e-06 26.5 0.0 4.5 4 1 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 OWF37071.1 - 1.6e-08 34.8 4.2 0.00024 21.4 2.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OWF37071.1 - 1.6e-08 34.7 0.0 0.0003 21.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37071.1 - 2.8e-07 30.4 1.1 7.1e-05 22.7 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF37071.1 - 2e-05 24.5 0.0 0.053 13.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) SurA_N_2 PF13623.6 OWF37071.1 - 0.00033 20.5 1.1 0.00094 19.1 0.4 1.8 1 1 1 2 2 2 1 SurA N-terminal domain DUF5580 PF17743.1 OWF37071.1 - 0.0011 17.6 0.0 0.49 8.9 0.0 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5580) Syntaxin PF00804.25 OWF37071.1 - 0.0021 17.8 2.5 0.5 10.0 0.2 2.3 1 1 0 2 2 2 2 Syntaxin Adenine_glyco PF03352.13 OWF37071.1 - 0.0065 16.3 0.1 0.0075 16.1 0.1 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase Caleosin PF05042.13 OWF37071.1 - 0.019 14.9 3.1 2.5 8.0 0.2 2.7 2 1 1 3 3 3 0 Caleosin related protein EF-hand_11 PF08976.11 OWF37071.1 - 0.032 15.1 0.3 1.9 9.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain DUF2312 PF10073.9 OWF37071.1 - 0.044 13.4 1.8 0.092 12.4 1.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) TerB PF05099.13 OWF37071.1 - 0.058 13.3 0.1 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TerB EF-hand_14 PF17959.1 OWF37071.1 - 0.074 13.4 0.3 5.6 7.4 0.0 2.7 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 OWF37071.1 - 0.18 12.0 2.6 9.3 6.5 0.1 3.1 1 1 2 3 3 3 0 Dockerin type I domain RRP7 PF12923.7 OWF37071.1 - 0.19 11.9 3.9 0.086 13.0 1.6 1.5 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain EF-hand_1 PF00036.32 OWF37072.1 - 1.8e-42 139.7 11.7 5.4e-10 38.1 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37072.1 - 5.6e-37 126.0 2.8 1.8e-18 66.8 1.4 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37072.1 - 4e-33 113.0 11.4 7.4e-16 57.8 0.7 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37072.1 - 4.6e-31 104.1 6.5 1.7e-09 36.8 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37072.1 - 1.3e-27 94.0 9.4 3.3e-07 29.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37072.1 - 1.4e-15 57.3 0.2 2.5e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37072.1 - 2.3e-09 37.1 0.6 0.00015 21.6 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37072.1 - 2.5e-08 34.2 0.0 0.004 17.4 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF37072.1 - 1.5e-06 29.0 0.0 0.0015 19.4 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 OWF37072.1 - 3.4e-05 23.8 0.0 0.041 13.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 OWF37072.1 - 0.00027 21.0 0.3 0.0024 17.9 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OWF37072.1 - 0.00038 20.6 4.5 0.056 13.6 0.4 2.9 2 2 1 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 OWF37072.1 - 0.00063 19.7 0.5 0.35 10.8 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 OWF37072.1 - 0.0012 17.5 0.0 0.0012 17.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF4497 PF14924.6 OWF37072.1 - 0.0024 18.3 0.0 1.4 9.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 OWF37072.1 - 0.0027 18.0 0.6 1.3 9.3 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF1103 PF06513.11 OWF37072.1 - 0.0033 17.1 3.4 0.004 16.8 3.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.13 OWF37072.1 - 0.0037 17.2 0.5 0.85 9.6 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF3349 PF11829.8 OWF37072.1 - 0.0099 16.6 0.6 3.7 8.4 0.0 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) SurA_N_2 PF13623.6 OWF37072.1 - 0.011 15.7 0.8 0.46 10.3 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 OWF37072.1 - 0.015 15.4 0.3 0.31 11.2 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Acetyltransf_11 PF13720.6 OWF37072.1 - 0.022 15.2 0.0 3.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 dCache_2 PF08269.11 OWF37072.1 - 0.035 13.3 0.1 2.5 7.2 0.0 2.1 1 1 1 2 2 2 0 Cache domain EF-hand_14 PF17959.1 OWF37072.1 - 0.038 14.3 0.1 8.2 6.9 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 OWF37072.1 - 0.059 13.0 0.5 0.25 11.0 0.5 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Poly_export PF02563.16 OWF37072.1 - 0.12 12.7 0.0 5.9 7.2 0.0 3.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein PY_rept_46 PF09689.10 OWF37072.1 - 0.19 12.3 2.5 37 5.0 0.0 3.0 2 1 1 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) EF-hand_1 PF00036.32 OWF37073.1 - 1.3e-30 102.6 14.6 2.9e-09 35.8 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37073.1 - 4e-30 104.1 11.7 6.9e-15 55.3 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37073.1 - 7.9e-28 94.0 13.5 2.9e-08 33.0 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37073.1 - 4.2e-23 81.0 14.7 4.5e-11 42.4 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF37073.1 - 4.1e-21 73.5 9.7 9.6e-06 24.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37073.1 - 5.5e-13 49.0 2.8 2.1e-05 24.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37073.1 - 8.1e-07 29.0 6.8 0.014 15.3 0.6 3.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37073.1 - 8.4e-05 22.9 4.8 0.015 15.6 0.8 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region CNOT1_TTP_bind PF16417.5 OWF37073.1 - 0.00061 19.0 0.8 0.59 9.3 0.1 2.2 1 1 1 2 2 2 2 CCR4-NOT transcription complex subunit 1 TTP binding domain EFhand_Ca_insen PF08726.10 OWF37073.1 - 0.00081 19.4 1.8 0.0025 17.8 0.1 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OWF37073.1 - 0.002 18.3 1.1 0.56 10.4 0.1 2.5 2 1 0 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 OWF37073.1 - 0.0022 17.9 3.3 2.1 8.3 0.0 3.2 1 1 2 4 4 4 2 Caleosin related protein Toprim_2 PF13155.6 OWF37073.1 - 0.0034 17.8 0.9 0.59 10.6 0.2 2.4 1 1 2 3 3 3 1 Toprim-like EF-hand_11 PF08976.11 OWF37073.1 - 0.005 17.7 0.6 1.2 10.1 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 OWF37073.1 - 0.018 15.0 1.2 1.1 9.2 0.2 2.5 2 1 1 3 3 3 0 Tellurite resistance protein TerB UBA_6 PF18039.1 OWF37073.1 - 0.029 14.3 0.2 0.08 12.9 0.2 1.8 1 0 0 1 1 1 0 UBA-like domain DUF4258 PF14076.6 OWF37073.1 - 0.047 14.1 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) PIN_8 PF18476.1 OWF37073.1 - 0.065 13.1 1.6 0.075 12.9 1.6 1.2 1 0 0 1 1 1 0 PIN like domain DUF5394 PF17372.2 OWF37073.1 - 0.066 12.8 6.2 1.9 8.0 1.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5394) PHB_acc_N PF07879.11 OWF37073.1 - 0.066 13.3 0.1 1.6 8.8 0.0 2.7 2 1 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain DUF3837 PF12939.7 OWF37073.1 - 0.13 12.7 2.2 0.61 10.5 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) EF-hand_10 PF14788.6 OWF37073.1 - 0.99 9.3 6.4 0.29 11.0 0.9 2.9 3 1 1 4 4 4 0 EF hand EF-hand_1 PF00036.32 OWF37074.1 - 1.3e-37 124.5 11.8 2.5e-09 36.0 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF37074.1 - 4.6e-32 109.7 10.3 3.7e-14 52.3 0.6 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 OWF37074.1 - 5e-32 110.2 3.0 1.3e-16 60.8 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37074.1 - 1.3e-26 90.2 4.4 2.3e-08 33.3 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37074.1 - 5e-20 70.0 8.1 9.9e-05 21.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37074.1 - 3.8e-14 52.8 0.8 3e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37074.1 - 1.1e-08 35.0 2.4 0.00095 19.1 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37074.1 - 2.4e-08 34.3 0.3 0.0029 17.9 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF37074.1 - 1.9e-05 24.6 0.0 0.018 15.0 0.0 3.0 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) DUF4497 PF14924.6 OWF37074.1 - 5.3e-05 23.6 0.1 0.0067 16.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) EF-hand_11 PF08976.11 OWF37074.1 - 0.00035 21.4 0.1 0.0062 17.4 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 OWF37074.1 - 0.00059 20.2 1.3 0.28 11.5 0.0 2.7 3 1 0 3 3 2 2 RNA polymerase Rpb4 Caleosin PF05042.13 OWF37074.1 - 0.00063 19.7 0.2 0.13 12.2 0.0 3.1 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 OWF37074.1 - 0.0019 16.8 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Flagellar_rod PF05149.12 OWF37074.1 - 0.0039 16.7 0.1 1.3 8.4 0.0 2.1 1 1 1 2 2 2 2 Paraflagellar rod protein EFhand_Ca_insen PF08726.10 OWF37074.1 - 0.0067 16.5 0.4 0.038 14.1 0.0 2.2 2 2 0 2 2 2 1 Ca2+ insensitive EF hand PheRS_DBD2 PF18554.1 OWF37074.1 - 0.012 15.6 0.1 0.041 13.9 0.0 1.9 2 0 0 2 2 1 0 PheRS DNA binding domain 2 DUF3349 PF11829.8 OWF37074.1 - 0.022 15.5 0.6 6 7.7 0.1 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) Fe_hyd_lg_C PF02906.14 OWF37074.1 - 0.025 14.3 1.6 0.07 12.8 1.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain SurA_N_2 PF13623.6 OWF37074.1 - 0.026 14.4 1.1 4.4 7.2 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain TerB PF05099.13 OWF37074.1 - 0.029 14.3 0.4 2.3 8.1 0.0 2.5 1 1 2 3 3 3 0 Tellurite resistance protein TerB Poly_export PF02563.16 OWF37074.1 - 0.043 14.1 0.0 0.52 10.6 0.0 2.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein Acetyltransf_11 PF13720.6 OWF37074.1 - 0.044 14.3 0.1 9.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Dockerin_1 PF00404.18 OWF37074.1 - 0.06 13.6 3.8 2 8.7 3.8 2.9 1 1 0 1 1 1 0 Dockerin type I domain CMD PF02627.20 OWF37074.1 - 0.11 12.5 0.1 8.3 6.5 0.0 2.7 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family Gly_acyl_tr_N PF06021.11 OWF37074.1 - 0.12 12.5 0.0 0.38 10.8 0.0 1.8 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase TFIIA_gamma_N PF02268.16 OWF37074.1 - 0.12 12.4 0.2 0.32 11.1 0.2 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Cas_Csa5 PF09702.10 OWF37074.1 - 0.15 12.3 0.8 0.98 9.7 0.1 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Kelch_4 PF13418.6 OWF37075.1 - 2.9e-42 142.4 11.1 4.1e-12 45.9 0.1 5.6 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 OWF37075.1 - 6.4e-41 137.7 12.8 2.2e-10 40.0 0.3 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OWF37075.1 - 1.4e-35 120.9 9.8 1.7e-11 44.1 0.3 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF37075.1 - 2e-31 107.2 8.3 1.3e-07 31.6 0.0 5.6 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OWF37075.1 - 3.4e-21 74.3 10.9 8.2e-06 25.6 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 OWF37075.1 - 2.4e-18 65.7 11.6 1.8e-06 27.8 0.1 6.0 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 OWF37076.1 - 1.9e-23 82.8 0.1 2.6e-13 50.2 0.0 3.4 2 1 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 OWF37076.1 - 1.6e-08 34.6 0.2 5.6e-08 32.8 0.2 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF2052 PF09747.9 OWF37077.1 - 1.3e-38 133.1 31.8 8.8e-37 127.2 28.6 2.7 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) MRP-S34 PF16053.5 OWF37077.1 - 0.034 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 PhyH PF05721.13 OWF37078.1 - 1.3e-20 74.5 0.0 2.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DinB_2 PF12867.7 OWF37078.1 - 0.055 14.0 0.0 0.49 10.9 0.0 2.2 2 0 0 2 2 2 0 DinB superfamily PhyH PF05721.13 OWF37079.1 - 2.2e-20 73.8 0.0 3.4e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMOP PF03782.17 OWF37079.1 - 0.033 14.3 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 AMOP domain PhyH PF05721.13 OWF37081.1 - 7e-24 85.3 0.0 1.1e-23 84.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2905 PF11146.8 OWF37081.1 - 0.22 11.7 0.1 0.4 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Ras PF00071.22 OWF37082.1 - 5.9e-43 146.3 0.0 6.9e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF37082.1 - 1.9e-15 57.2 0.0 2.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF37082.1 - 2.3e-05 24.0 0.0 3.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Flavodoxin_2 PF02525.17 OWF37083.1 - 5.2e-36 124.2 0.0 6.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OWF37083.1 - 4.9e-06 26.4 0.0 7.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase TMEM251 PF15190.6 OWF37084.1 - 1.7e-26 92.7 1.3 3e-26 91.9 1.3 1.4 1 1 0 1 1 1 1 Transmembrane protein 251 Ins134_P3_kin PF05770.11 OWF37085.1 - 6.8e-54 182.4 0.5 1.1e-53 181.8 0.1 1.5 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 OWF37085.1 - 1e-18 67.5 0.0 2.3e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ALS2CR8 PF15299.6 OWF37086.1 - 3.9e-10 40.0 7.3 8.1e-10 39.0 7.3 1.6 1 1 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 PHD PF00628.29 OWF37086.1 - 3.4e-05 23.7 15.1 3.4e-05 23.7 15.1 2.5 1 1 1 2 2 2 2 PHD-finger zf-H2C2_2 PF13465.6 OWF37086.1 - 0.15 12.5 3.4 9.2 6.9 0.1 3.1 2 0 0 2 2 2 0 Zinc-finger double domain dCMP_cyt_deam_1 PF00383.23 OWF37087.1 - 4.3e-15 55.4 0.2 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OWF37087.1 - 1.9e-12 47.1 0.1 5.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 OWF37087.1 - 0.00066 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Bd3614-like deaminase GoLoco PF02188.17 OWF37087.1 - 2.1 8.0 3.7 6.9 6.3 0.0 3.0 3 0 0 3 3 3 0 GoLoco motif CcdB PF01845.17 OWF37089.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 CcdB protein Viral_env_E26 PF11050.8 OWF37089.1 - 0.18 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 PIH1 PF08190.12 OWF37090.1 - 1.9e-58 196.6 1.4 7.8e-58 194.6 1.4 2.1 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 OWF37090.1 - 1.2e-30 105.8 0.2 3.5e-30 104.3 0.2 1.9 1 0 0 1 1 1 1 PIH1 CS-like domain Tropomyosin PF00261.20 OWF37091.1 - 0.00013 21.5 20.0 0.00017 21.0 20.0 1.1 1 0 0 1 1 1 1 Tropomyosin HAUS6_N PF14661.6 OWF37091.1 - 0.004 16.8 16.4 0.35 10.4 9.8 2.1 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 6 N-terminus ZapB PF06005.12 OWF37091.1 - 0.028 14.8 21.6 0.37 11.3 1.5 3.5 1 1 3 4 4 4 0 Cell division protein ZapB DLP_helical PF18709.1 OWF37091.1 - 0.082 12.1 13.3 0.72 9.0 4.2 2.7 1 1 1 2 2 2 0 Dynamin-like helical domain NUDE_C PF04880.13 OWF37091.1 - 0.26 11.8 13.6 0.064 13.7 4.2 2.4 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Spc7 PF08317.11 OWF37091.1 - 0.26 10.1 22.5 0.87 8.4 14.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein YojJ PF10372.9 OWF37091.1 - 0.33 11.1 3.9 0.26 11.4 1.1 2.2 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Exonuc_VII_L PF02601.15 OWF37091.1 - 0.35 10.4 10.8 0.47 10.0 10.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit T3SSipB PF16535.5 OWF37091.1 - 0.37 11.3 9.6 1 9.8 4.9 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF1664 PF07889.12 OWF37091.1 - 0.53 10.3 8.7 3.5 7.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OWF37091.1 - 0.54 10.3 23.8 5.5 7.0 15.4 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 OWF37091.1 - 0.91 9.8 12.8 0.54 10.5 0.4 3.4 2 2 2 4 4 4 0 Haemolysin XhlA Sec8_exocyst PF04048.14 OWF37091.1 - 0.91 9.4 7.0 3.1 7.7 2.0 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Herpes_UL6 PF01763.16 OWF37091.1 - 0.96 7.9 8.9 0.49 8.9 6.4 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF4164 PF13747.6 OWF37091.1 - 1 9.7 15.2 5.1 7.4 7.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) CLZ PF16526.5 OWF37091.1 - 1.1 9.6 17.1 0.48 10.8 4.8 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 OWF37091.1 - 1.4 9.0 22.9 0.95 9.5 13.7 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 OWF37091.1 - 2.7 8.5 13.1 3.2 8.3 0.2 2.5 2 1 1 3 3 3 0 Spectrin repeat DUF2968 PF11180.8 OWF37091.1 - 2.7 7.6 15.0 0.81 9.3 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) GCN5L1 PF06320.13 OWF37091.1 - 3.5 7.8 13.4 0.25 11.5 0.7 2.9 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) TACC_C PF05010.14 OWF37091.1 - 4.4 7.0 22.1 4.7 6.9 14.3 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4407 PF14362.6 OWF37091.1 - 6.6 6.0 14.9 14 5.0 14.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LPP PF04728.13 OWF37091.1 - 7.5 7.0 9.3 5.6 7.4 0.2 3.9 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Rootletin PF15035.6 OWF37091.1 - 7.5 6.5 21.4 23 5.0 12.0 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF724 PF05266.14 OWF37091.1 - 7.7 6.3 18.2 9.5 6.0 8.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3552 PF12072.8 OWF37091.1 - 9.8 5.5 23.7 28 4.0 23.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Bactofilin PF04519.13 OWF37093.1 - 6.3e-09 36.0 1.6 1.4e-08 34.9 0.5 1.8 2 0 0 2 2 2 1 Polymer-forming cytoskeletal DUF748 PF05359.11 OWF37093.1 - 0.0051 17.0 0.2 0.92 9.7 0.2 2.8 1 1 0 1 1 1 1 Domain of Unknown Function (DUF748) gp12-short_mid PF09089.10 OWF37093.1 - 0.0063 16.6 8.2 4.7 7.4 0.7 3.5 1 1 3 4 4 4 4 Phage short tail fibre protein gp12, middle domain Chorion_1 PF01723.16 OWF37093.1 - 0.011 15.7 5.2 0.13 12.2 1.4 2.1 1 1 1 2 2 2 0 Chorion protein AsmA_2 PF13502.6 OWF37093.1 - 0.18 11.3 4.2 1.1 8.7 4.2 2.2 1 1 0 1 1 1 0 AsmA-like C-terminal region SSF PF00474.17 OWF37094.1 - 9e-35 120.3 30.3 1.3e-34 119.7 30.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4805 PF16063.5 OWF37094.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) SSF PF00474.17 OWF37095.1 - 9.3e-36 123.6 28.4 1.2e-35 123.2 28.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Y_phosphatase PF00102.27 OWF37096.1 - 5.7e-108 359.9 2.9 5.8e-65 219.1 0.1 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 OWF37096.1 - 1.9e-05 24.8 1.1 4.8e-05 23.5 1.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain DSPc PF00782.20 OWF37096.1 - 0.00027 20.7 0.7 0.26 11.1 0.1 2.9 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF37096.1 - 0.006 16.6 0.2 0.072 13.0 0.0 2.7 3 0 0 3 3 3 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OWF37096.1 - 0.023 14.8 0.1 0.36 10.9 0.0 2.7 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 OWF37097.1 - 6.7e-112 372.8 0.2 1.3e-72 244.2 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 OWF37097.1 - 4e-06 27.0 1.2 1.1e-05 25.6 1.2 1.8 1 0 0 1 1 1 1 F5/8 type C domain DSPc PF00782.20 OWF37097.1 - 0.00036 20.4 0.4 0.035 13.9 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF37097.1 - 0.017 15.2 0.1 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate Mid2 PF04478.12 OWF37097.1 - 0.053 13.4 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 OWF37097.1 - 0.084 13.8 0.0 0.43 11.5 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Y_phosphatase3 PF13350.6 OWF37097.1 - 0.11 12.4 0.5 0.43 10.5 0.3 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family LCAT PF02450.15 OWF37098.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OWF37098.1 - 0.12 11.6 0.1 7.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 OWF37099.1 - 4.8e-05 22.7 0.0 8.6e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF3839 PF12943.7 OWF37099.1 - 0.042 13.3 0.1 6.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3839) DNA_pol_B_exo1 PF03104.19 OWF37100.1 - 0.00071 18.8 0.1 0.0017 17.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain LCAT PF02450.15 OWF37101.1 - 0.00039 19.7 0.0 0.0019 17.4 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase TMEM238 PF15125.6 OWF37101.1 - 0.056 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 TMEM238 protein family DUF3371 PF11851.8 OWF37102.1 - 6.3 7.9 7.1 1.6 9.8 0.4 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3371) LPD13 PF18825.1 OWF37103.1 - 0.0053 16.5 0.9 0.01 15.6 0.9 1.4 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 13 Transposase_22 PF02994.14 OWF37103.1 - 0.53 10.5 4.7 0.15 12.2 1.0 2.0 2 1 0 2 2 2 0 L1 transposable element RBD-like domain EGF PF00008.27 OWF37105.1 - 2e-171 555.5 340.8 3.4e-09 36.8 3.8 23.4 23 0 0 23 23 23 22 EGF-like domain hEGF PF12661.7 OWF37105.1 - 2e-140 453.3 313.0 7.3e-08 32.8 7.8 24.2 23 0 0 23 23 23 22 Human growth factor-like EGF EGF_CA PF07645.15 OWF37105.1 - 2.4e-78 258.1 341.2 2e-05 24.7 7.3 22.4 18 3 4 22 22 22 22 Calcium-binding EGF domain EGF_2 PF07974.13 OWF37105.1 - 3.6e-29 100.8 375.1 0.00018 21.8 7.6 23.5 22 2 2 24 24 24 21 EGF-like domain cEGF PF12662.7 OWF37105.1 - 3.2e-20 71.7 306.6 0.00014 21.7 2.7 28.5 30 5 0 30 30 30 20 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF37105.1 - 6.9e-19 67.8 313.3 0.083 13.2 9.1 23.3 7 5 16 23 23 23 15 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 OWF37105.1 - 0.0092 16.3 3.7 0.0092 16.3 3.7 23.4 22 1 1 23 23 23 15 Pvs28 EGF domain EGF_3 PF12947.7 OWF37105.1 - 0.018 15.2 5.9 0.018 15.2 5.9 24.0 20 4 3 23 23 23 0 EGF domain Actin PF00022.19 OWF37106.1 - 5.2e-150 499.6 0.0 1.7e-149 497.9 0.0 1.6 1 1 0 1 1 1 1 Actin 7tm_1 PF00001.21 OWF37107.1 - 0.0056 16.0 16.3 0.0082 15.5 16.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 OWF37107.1 - 0.36 10.6 13.5 0.023 14.5 8.6 1.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OWF37108.1 - 6.9e-07 28.9 8.6 6.9e-07 28.9 8.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 OWF37108.1 - 7.6e-07 29.1 7.6 1.3e-06 28.4 7.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 STE3 PF02076.15 OWF37108.1 - 1.2e-05 24.7 4.1 0.00077 18.8 1.0 2.3 2 0 0 2 2 2 2 Pheromone A receptor DUF5090 PF17009.5 OWF37108.1 - 0.36 10.8 15.7 0.6 10.0 3.3 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF5090) Methyltransf_3 PF01596.17 OWF37109.1 - 4.2e-46 156.8 0.0 6.2e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OWF37109.1 - 1.8e-08 35.4 0.0 4.7e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OWF37109.1 - 0.00052 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 OWF37109.1 - 0.043 13.4 0.0 0.093 12.4 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 OWF37110.1 - 3.5e-45 153.8 0.0 4.7e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OWF37110.1 - 1.7e-08 35.5 0.0 3.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF37110.1 - 3.7e-06 26.7 0.0 5.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OWF37110.1 - 0.0019 18.8 0.0 0.0044 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF37110.1 - 0.003 17.3 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 OWF37110.1 - 0.0066 17.1 0.0 0.018 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0146 PF03686.13 OWF37110.1 - 0.013 15.4 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) DUF2913 PF11140.8 OWF37110.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Methyltransf_22 PF13383.6 OWF37111.1 - 3.2e-15 56.4 3.0 3.2e-15 56.4 3.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF37111.1 - 6.8e-08 32.7 0.1 1.1e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain PAS_11 PF14598.6 OWF37112.1 - 1.3e-19 70.4 0.9 6e-13 48.9 0.0 3.8 4 0 0 4 4 4 2 PAS domain PAS_3 PF08447.12 OWF37112.1 - 3.8e-18 65.6 0.1 5.9e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OWF37112.1 - 3.3e-17 62.5 0.0 3.9e-09 36.5 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 OWF37112.1 - 1.5e-08 34.8 0.0 9.9e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 PAS domain HLH PF00010.26 OWF37112.1 - 0.0045 16.9 0.6 0.0045 16.9 0.6 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 OWF37112.1 - 0.052 13.8 0.0 5.2 7.4 0.0 2.5 2 0 0 2 2 2 0 PAS fold EC042_2821 PF18740.1 OWF37113.1 - 0.006 16.5 0.8 0.006 16.5 0.8 3.0 3 0 0 3 3 3 1 EC042_2821-lke REase CC2-LZ PF16516.5 OWF37113.1 - 2.8 8.3 52.7 0.62 10.5 0.1 8.1 5 3 1 7 7 7 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 OWF37113.1 - 7.8 5.3 79.2 0.12 11.2 5.1 6.2 1 1 5 6 6 6 0 Spc7 kinetochore protein EMC3_TMCO1 PF01956.16 OWF37114.1 - 0.04 13.6 0.3 0.094 12.4 0.1 1.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF4710 PF15828.5 OWF37115.1 - 0.005 16.9 0.6 0.079 13.1 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4710) Ependymin PF00811.18 OWF37116.1 - 1.9e-34 118.6 0.6 2.6e-34 118.2 0.6 1.2 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF37117.1 - 5.9e-33 113.8 0.3 8.3e-33 113.3 0.3 1.2 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF37118.1 - 4.3e-30 104.6 0.1 5.7e-30 104.2 0.1 1.2 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF37119.1 - 1e-38 132.5 0.0 1.3e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF37120.1 - 1.1e-34 119.4 0.0 1.9e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Ependymin Glyco_hydro_65m PF03632.15 OWF37121.1 - 3e-48 164.6 0.0 3.9e-42 144.5 0.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65m PF03632.15 OWF37122.1 - 1.6e-49 168.8 0.0 2.6e-42 145.1 0.3 2.6 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.9 OWF37122.1 - 6.1e-05 21.6 0.0 0.016 13.6 0.0 3.1 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65m PF03632.15 OWF37123.1 - 1.6e-43 149.0 0.0 1e-37 129.9 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.9 OWF37123.1 - 1.4e-07 30.3 0.2 0.00057 18.3 0.3 3.0 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Ank_2 PF12796.7 OWF37124.1 - 1.8e-65 217.5 25.7 5.9e-18 65.2 0.2 6.1 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF37124.1 - 6.6e-48 160.5 7.4 3.3e-10 40.3 0.1 10.0 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37124.1 - 6.8e-42 141.0 12.2 2.2e-07 31.0 0.1 8.3 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37124.1 - 8.6e-34 111.8 10.0 0.0033 17.8 0.0 12.5 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 OWF37124.1 - 1.2e-26 92.0 12.2 0.0001 22.6 0.2 11.6 12 0 0 12 12 12 5 Ankyrin repeat SOCS_box PF07525.16 OWF37124.1 - 1.1 9.7 3.5 2.4 8.6 3.5 1.6 1 0 0 1 1 1 0 SOCS box Ank_2 PF12796.7 OWF37125.1 - 1.1e-65 218.3 11.1 1.1e-15 58.0 0.3 5.9 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF37125.1 - 6.4e-45 151.0 4.8 1.6e-08 34.9 0.0 9.4 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37125.1 - 2.6e-37 126.4 12.4 8.5e-07 29.1 0.2 8.7 6 1 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37125.1 - 6.2e-34 112.2 5.8 0.039 14.5 0.0 12.5 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 OWF37125.1 - 6.5e-30 102.2 8.9 0.0012 19.2 0.1 11.8 11 1 1 12 12 12 8 Ankyrin repeat SOCS_box PF07525.16 OWF37125.1 - 0.057 13.8 2.6 0.11 12.8 2.6 1.5 1 0 0 1 1 1 0 SOCS box CNH PF00780.22 OWF37127.1 - 3.1e-62 210.7 0.4 6.4e-62 209.7 0.4 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 OWF37127.1 - 2.4e-52 177.9 0.0 7.4e-51 173.0 0.0 2.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37127.1 - 1.5e-26 93.2 0.0 4e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase KELK PF15796.5 OWF37127.1 - 6.4e-18 65.0 17.0 6.4e-18 65.0 17.0 7.8 4 2 2 7 7 5 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase C1_1 PF00130.22 OWF37127.1 - 3.1e-10 39.8 8.5 7e-10 38.6 8.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DMPK_coil PF08826.10 OWF37127.1 - 1.5e-08 34.6 8.8 1.5e-08 34.6 8.8 8.9 6 3 3 9 9 8 2 DMPK coiled coil domain like PBD PF00786.28 OWF37127.1 - 1.4e-06 28.5 5.6 0.0017 18.6 0.1 3.9 3 0 0 3 3 3 2 P21-Rho-binding domain PH PF00169.29 OWF37127.1 - 5.6e-06 26.8 0.0 4e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OWF37127.1 - 5.7e-06 25.8 0.0 2.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.11 OWF37127.1 - 0.00019 21.7 16.7 0.00019 21.7 16.7 5.2 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) Pkinase_C PF00433.24 OWF37127.1 - 0.00078 20.1 2.6 0.0035 18.0 2.6 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 OWF37127.1 - 0.054 13.4 0.8 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3138 PF11336.8 OWF37127.1 - 0.26 9.9 3.0 0.53 8.8 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Lectin_C PF00059.21 OWF37128.1 - 1.7e-08 35.1 0.5 7.7e-08 33.0 0.5 2.3 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF37128.1 - 3.6e-08 33.3 0.2 1.1e-07 31.7 0.2 1.9 1 0 0 1 1 1 1 PAN domain DUF3761 PF12587.8 OWF37128.1 - 0.0014 19.0 10.1 51 4.4 0.1 6.3 5 1 1 6 6 6 0 Protein of unknown function (DUF3761) PilJ_C PF18223.1 OWF37128.1 - 0.0075 16.7 0.0 0.036 14.5 0.0 2.2 1 0 0 1 1 1 1 Pili PilJ C-terminal domain Scaffolding_pro PF11418.8 OWF37128.1 - 0.011 16.2 0.5 0.011 16.2 0.5 2.6 3 0 0 3 3 3 0 Phi29 scaffolding protein ATG16 PF08614.11 OWF37128.1 - 0.073 13.3 34.6 0.04 14.1 2.0 5.0 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OWF37128.1 - 0.47 10.5 33.2 0.1 12.7 8.8 4.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein HsbA PF12296.8 OWF37128.1 - 2.2 8.7 9.6 0.35 11.3 0.5 3.7 3 2 0 3 3 3 0 Hydrophobic surface binding protein A Serine_rich PF08824.10 OWF37128.1 - 7.4 6.5 25.1 1.9 8.5 4.9 4.7 3 1 1 4 4 4 0 Serine rich protein interaction domain Filament PF00038.21 OWF37128.1 - 8.5 5.9 39.6 0.34 10.5 1.5 5.0 1 1 4 5 5 5 0 Intermediate filament protein Kinesin PF00225.23 OWF37129.1 - 2.2e-54 184.6 0.0 5e-54 183.5 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF37129.1 - 1.6e-13 50.9 0.0 3.3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding MIF4G PF02854.19 OWF37130.1 - 1.5e-19 70.5 3.0 7.3e-19 68.2 1.3 2.5 2 0 0 2 2 2 1 MIF4G domain RRM_1 PF00076.22 OWF37130.1 - 0.0021 17.9 0.8 2.1 8.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COR PF16095.5 OWF37131.1 - 9.1e-48 162.6 0.0 1.7e-46 158.5 0.1 2.9 3 0 0 3 3 3 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF37131.1 - 5.1e-24 84.8 0.4 1.5e-23 83.3 0.1 2.1 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase MBT PF02820.18 OWF37131.1 - 1.1e-18 67.3 0.0 3.7e-18 65.6 0.0 2.0 1 0 0 1 1 1 1 mbt repeat LRR_4 PF12799.7 OWF37131.1 - 1.3e-18 66.7 23.9 0.00029 21.2 3.3 7.1 3 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF37131.1 - 1.7e-18 66.1 15.7 1.2e-06 28.2 3.3 5.4 3 1 2 5 5 5 4 Leucine rich repeat TIR_2 PF13676.6 OWF37131.1 - 8.8e-15 55.4 0.0 5.6e-10 39.9 0.0 2.8 2 0 0 2 2 2 2 TIR domain Ras PF00071.22 OWF37131.1 - 7.1e-14 51.7 0.0 2e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 OWF37131.1 - 0.00034 20.5 0.0 3.7 7.4 0.0 3.8 3 0 0 3 3 3 1 RsgA GTPase Arf PF00025.21 OWF37131.1 - 0.00062 19.3 0.1 0.0022 17.5 0.1 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF37131.1 - 0.0065 15.8 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_1 PF00036.32 OWF37131.1 - 0.0075 15.8 0.1 0.035 13.7 0.1 2.2 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OWF37131.1 - 0.016 14.7 0.2 0.068 12.7 0.2 2.1 1 0 0 1 1 1 0 EF hand PduV-EutP PF10662.9 OWF37131.1 - 0.019 14.7 0.1 0.93 9.2 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OWF37131.1 - 0.023 14.7 0.0 0.12 12.5 0.0 2.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase EF-hand_6 PF13405.6 OWF37131.1 - 0.041 13.8 0.0 0.36 10.9 0.0 2.7 1 0 0 1 1 1 0 EF-hand domain LRR_5 PF13306.6 OWF37131.1 - 0.098 12.6 0.2 0.76 9.7 0.1 2.4 1 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF37131.1 - 0.1 13.2 14.4 19 6.3 0.1 7.8 8 0 0 8 8 6 0 Leucine Rich Repeat AAA_23 PF13476.6 OWF37131.1 - 0.13 12.8 15.8 1.2 9.7 12.7 3.4 3 0 0 3 3 3 0 AAA domain LRR_9 PF14580.6 OWF37131.1 - 0.37 10.3 3.4 5.1 6.6 1.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeat MecA PF05389.12 OWF37131.1 - 0.45 10.1 10.0 1.4 8.5 10.0 1.8 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) RNA_pol_3_Rpc31 PF11705.8 OWF37131.1 - 2.5 8.3 18.3 6.9 6.9 18.3 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PIEZO PF15917.5 OWF37131.1 - 3.7 7.0 9.8 8.5 5.8 9.8 1.6 1 0 0 1 1 1 0 Piezo Sulfotransfer_2 PF03567.14 OWF37132.1 - 3.7e-22 79.4 0.5 3.9e-18 66.3 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family LZ_Tnp_IS481 PF13011.6 OWF37132.1 - 0.0032 18.0 0.0 3 8.5 0.0 2.6 2 0 0 2 2 2 2 leucine-zipper of insertion element IS481 Sulfotransfer_2 PF03567.14 OWF37133.1 - 1.1e-22 81.1 0.4 1.3e-18 67.8 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF37134.1 - 3.8e-23 82.7 0.2 1.7e-19 70.7 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family SCO1-SenC PF02630.14 OWF37136.1 - 8.9e-46 155.1 0.1 1.4e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 OWF37136.1 - 4.1e-06 27.0 0.1 9.4e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OWF37136.1 - 8.3e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Exo_endo_phos_2 PF14529.6 OWF37137.1 - 2.4e-08 33.8 0.9 5.8e-08 32.6 0.3 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OWF37137.1 - 1.5e-05 24.7 0.0 4.3e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_1 PF00001.21 OWF37138.1 - 5.7e-08 32.4 10.3 8e-08 31.9 10.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF37138.1 - 0.00011 22.0 7.4 0.00011 22.0 7.4 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4059 PF13268.6 OWF37138.1 - 0.0083 16.5 0.6 0.042 14.3 0.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4059) LMF1 PF06762.14 OWF37138.1 - 0.028 13.6 2.1 0.034 13.3 2.1 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF4293 PF14126.6 OWF37138.1 - 0.16 12.2 4.8 0.51 10.6 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Saf_2TM PF18303.1 OWF37138.1 - 0.38 10.3 4.0 0.2 11.3 0.7 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain TMC PF07810.13 OWF37139.1 - 3.8e-30 104.7 1.6 1.3e-29 103.0 1.6 2.0 1 0 0 1 1 1 1 TMC domain TIM21 PF08294.11 OWF37139.1 - 0.11 12.3 0.6 8.2 6.3 0.1 2.5 2 0 0 2 2 2 0 TIM21 CENP-B_N PF04218.13 OWF37139.1 - 0.13 11.9 0.1 0.32 10.7 0.1 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Anoctamin PF04547.12 OWF37139.1 - 1.2 7.8 13.2 0.032 13.1 3.5 2.7 1 1 1 3 3 3 0 Calcium-activated chloride channel Ig_2 PF13895.6 OWF37142.1 - 4.3e-06 27.0 0.9 5.6e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 OWF37142.1 - 1.3e-05 25.7 0.0 2.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF37142.1 - 0.00049 20.1 0.0 0.00097 19.2 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF37142.1 - 0.0013 18.9 0.0 0.0033 17.6 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 OWF37142.1 - 0.0015 18.7 0.2 0.26 11.5 0.2 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF37142.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Homeodomain PF00046.29 OWF37143.1 - 3.7e-24 84.3 5.1 8.7e-24 83.1 5.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF37143.1 - 0.0071 16.2 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain SART-1 PF03343.13 OWF37143.1 - 0.6 8.6 12.1 0.012 14.2 5.9 1.3 2 0 0 2 2 2 0 SART-1 family Sfi1 PF08457.10 OWF37145.1 - 2.2e-15 56.2 235.6 3e-05 22.8 26.1 10.8 2 2 8 10 10 10 9 Sfi1 spindle body protein TRAP-gamma PF07074.12 OWF37147.1 - 4.5e-86 286.7 4.5 5.1e-86 286.5 4.5 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Renin_r PF07850.14 OWF37147.1 - 0.071 13.7 0.9 0.11 13.1 0.2 1.7 1 1 0 2 2 2 0 Renin receptor-like protein ATP_synt_H PF05493.13 OWF37147.1 - 0.31 11.5 2.4 4.6 7.8 0.0 2.9 3 0 0 3 3 3 0 ATP synthase subunit H DUF5391 PF17369.2 OWF37147.1 - 0.44 10.6 5.0 0.85 9.7 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5391) YoaP PF14268.6 OWF37147.1 - 2.7 7.6 4.9 1.9 8.0 2.5 1.9 2 0 0 2 2 2 0 YoaP-like DUF2970 PF11174.8 OWF37148.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2970) OAD_gamma PF04277.13 OWF37148.1 - 4.9 7.8 9.1 46 4.7 0.4 3.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Fumerase_C PF05683.12 OWF37149.1 - 2.2e-90 301.5 0.1 6.9e-90 299.9 0.0 1.8 2 0 0 2 2 2 1 Fumarase C-terminus Fumerase PF05681.14 OWF37149.1 - 8.9e-87 290.9 0.0 1.3e-86 290.4 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Colipase_C PF02740.14 OWF37149.1 - 0.028 14.6 1.5 0.036 14.2 0.1 1.9 2 0 0 2 2 2 0 Colipase, C-terminal domain IBN_N PF03810.19 OWF37149.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain BTB PF00651.31 OWF37150.1 - 6.2e-15 55.4 0.1 7.7e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF727 PF05303.12 OWF37150.1 - 0.084 12.9 0.1 0.95 9.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF727) MIB_HERC2 PF06701.13 OWF37152.1 - 1.1e-55 185.7 31.4 4.9e-23 81.2 4.6 5.6 5 0 0 5 5 5 4 Mib_herc2 SH3_15 PF18346.1 OWF37152.1 - 7e-40 135.2 29.4 3.3e-13 49.8 0.3 6.4 7 0 0 7 7 7 4 Mind bomb SH3 repeat domain Ank_2 PF12796.7 OWF37152.1 - 3.1e-29 101.4 0.1 1.2e-07 32.3 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF37152.1 - 1.1e-25 89.4 0.4 2.7e-07 30.7 0.0 7.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF37152.1 - 3.5e-21 75.3 2.9 0.0012 19.3 0.1 6.7 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF37152.1 - 1.7e-15 56.6 0.4 0.00073 19.9 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 OWF37152.1 - 1.2e-14 52.9 0.1 0.81 10.4 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat ZZ PF00569.17 OWF37152.1 - 8.4e-06 25.5 28.3 1.2e-05 25.0 6.1 3.8 4 0 0 4 4 4 2 Zinc finger, ZZ type R3H-assoc PF13902.6 OWF37152.1 - 0.48 10.8 4.0 1.2 9.6 4.0 1.6 1 0 0 1 1 1 0 R3H-associated N-terminal domain PLAC8 PF04749.17 OWF37153.1 - 9.4e-13 49.0 12.5 1.5e-12 48.4 12.5 1.3 1 0 0 1 1 1 1 PLAC8 family STE3 PF02076.15 OWF37154.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Pheromone A receptor Globin PF00042.22 OWF37155.1 - 1.8e-11 44.6 0.0 2.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Globin FdsD PF11390.8 OWF37155.1 - 0.087 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Ssu72 PF04722.13 OWF37156.1 - 2.7e-85 284.8 0.0 3.1e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein EAL PF00563.20 OWF37156.1 - 0.069 12.6 0.1 0.15 11.6 0.1 1.5 2 0 0 2 2 2 0 EAL domain WD40 PF00400.32 OWF37157.1 - 2.3e-38 129.5 17.3 2.1e-08 34.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF37157.1 - 4.3e-17 62.2 3.2 0.00018 21.8 0.1 6.2 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF37157.1 - 4.2e-07 30.0 2.9 0.017 15.0 0.2 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OWF37157.1 - 0.0033 15.5 0.2 0.18 9.8 0.2 2.3 2 1 0 2 2 2 2 IKI3 family Acyl_transf_3 PF01757.22 OWF37158.1 - 6e-19 68.3 33.8 8.9e-19 67.7 33.8 1.2 1 0 0 1 1 1 1 Acyltransferase family YqzL PF14006.6 OWF37158.1 - 3.1 8.2 6.1 0.22 11.9 0.3 2.0 2 0 0 2 2 2 0 YqzL-like protein F5_F8_type_C PF00754.25 OWF37161.1 - 6.1e-19 68.4 0.1 7.9e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 F5/8 type C domain PAN_1 PF00024.26 OWF37161.1 - 1e-05 25.4 0.6 2.6e-05 24.1 0.6 1.6 1 0 0 1 1 1 1 PAN domain NAD_binding_10 PF13460.6 OWF37162.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding PAC2 PF09754.9 OWF37162.1 - 0.079 13.0 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 PAC2 family Aldedh PF00171.22 OWF37163.1 - 1.1e-102 344.0 0.0 1.4e-102 343.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 7TM_GPCR_Srw PF10324.9 OWF37164.1 - 6.6e-17 61.8 26.0 8.5e-17 61.4 26.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF37164.1 - 2.3e-13 50.1 21.0 2.8e-12 46.5 20.8 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF37164.1 - 4.1e-07 29.9 11.4 4.1e-07 29.9 11.4 2.6 2 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 OWF37164.1 - 0.0032 17.4 1.6 0.0032 17.4 1.6 3.5 3 1 1 4 4 4 1 Caenorhabditis serpentine receptor-like protein, class xa Acetyltransf_1 PF00583.25 OWF37165.1 - 3.9e-11 43.2 0.0 5.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF37165.1 - 5.3e-07 30.0 0.0 9.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OWF37165.1 - 3.1e-05 24.2 0.0 4.5e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF37165.1 - 3.6e-05 23.7 0.0 5.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OWF37165.1 - 0.00035 21.2 0.0 0.0005 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF37165.1 - 0.0011 18.9 0.0 0.0079 16.1 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 OWF37165.1 - 0.065 13.4 0.2 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 OWF37166.1 - 3.5e-10 40.1 0.0 4.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OWF37166.1 - 2.9e-07 30.8 0.0 3.6e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF37166.1 - 6.7e-07 29.6 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF37166.1 - 7.3e-05 22.7 0.0 0.0001 22.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OWF37166.1 - 0.0022 18.7 0.0 0.0028 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1282 PF06930.12 OWF37167.1 - 0.17 11.6 2.8 0.18 11.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF4570 PF15134.6 OWF37169.1 - 1.6e-20 73.2 3.8 2.2e-20 72.7 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) zf-C2H2_4 PF13894.6 OWF37170.1 - 1.1e-27 94.3 192.4 0.0057 17.4 1.4 25.6 26 0 0 26 26 25 16 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF37170.1 - 1.6e-26 91.3 188.4 0.002 18.5 3.3 24.4 25 0 0 25 25 24 14 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF37170.1 - 1.6e-08 34.6 101.3 0.056 13.7 4.4 18.1 19 1 1 20 20 20 8 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF37170.1 - 3.9e-07 30.2 1.1 3.9e-07 30.2 1.1 21.7 24 1 0 24 24 22 8 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF37170.1 - 3.8e-06 26.8 2.8 0.00092 19.1 0.4 17.4 18 0 0 18 18 18 5 C2H2-type zinc finger GAGA PF09237.11 OWF37170.1 - 0.0045 16.8 1.4 0.0045 16.8 1.4 6.8 7 1 0 7 7 7 1 GAGA factor ROS_MUCR PF05443.11 OWF37170.1 - 0.0069 16.4 3.9 1.9 8.6 0.3 4.4 3 0 0 3 3 3 1 ROS/MUCR transcriptional regulator protein zf-met PF12874.7 OWF37170.1 - 0.0085 16.5 2.7 0.0085 16.5 2.7 18.7 24 0 0 24 24 23 8 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OWF37170.1 - 0.028 14.8 0.3 0.028 14.8 0.3 15.5 7 3 7 15 15 15 0 C2H2 type zinc-finger (2 copies) zf-TFIIB PF13453.6 OWF37170.1 - 0.64 9.4 3.6 5.7 6.4 0.0 4.6 4 0 0 4 4 4 0 Transcription factor zinc-finger DUF2423 PF10338.9 OWF37170.1 - 4.7 7.5 7.3 19 5.6 7.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) zf-Di19 PF05605.12 OWF37170.1 - 5.2 7.4 120.6 0.16 12.3 1.9 18.0 16 3 2 19 19 19 0 Drought induced 19 protein (Di19), zinc-binding Mito_carr PF00153.27 OWF37171.1 - 2e-43 146.2 6.3 1.5e-18 66.5 0.9 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SNF PF00209.18 OWF37172.1 - 1.9e-130 436.0 28.0 5e-129 431.3 28.0 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family RhoGEF PF00621.20 OWF37173.1 - 4.5e-34 118.3 4.0 1.6e-33 116.5 4.0 2.0 1 0 0 1 1 1 1 RhoGEF domain UNC-79 PF14776.6 OWF37173.1 - 2.8e-05 23.1 0.2 5.1e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 RBD PF02196.15 OWF37173.1 - 0.0014 18.7 0.0 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 Raf-like Ras-binding domain PPP1R35_C PF15503.6 OWF37175.1 - 5.8e-31 107.2 4.7 1.5e-30 105.9 4.7 1.8 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Fer2_3 PF13085.6 OWF37176.1 - 2.4e-32 111.2 0.1 5e-32 110.2 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OWF37176.1 - 2.4e-09 37.6 7.2 2.4e-09 37.6 7.2 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OWF37176.1 - 9.5e-08 32.4 7.8 9.5e-08 32.4 7.8 3.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OWF37176.1 - 2e-07 31.0 3.3 2e-07 31.0 3.3 2.7 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 OWF37176.1 - 0.0099 16.5 7.9 0.0099 16.5 7.9 3.1 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 OWF37176.1 - 0.025 14.7 8.2 0.025 14.7 8.2 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer2 PF00111.27 OWF37176.1 - 0.2 11.6 6.3 0.077 13.0 1.4 2.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain PDEase_I PF00233.19 OWF37177.1 - 9.6e-84 280.8 1.3 1.7e-83 280.0 0.4 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase LRR_4 PF12799.7 OWF37178.1 - 4.7e-09 36.4 4.4 0.017 15.5 0.9 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF37178.1 - 1e-06 28.4 4.5 0.014 15.2 0.3 3.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 OWF37178.1 - 2.3e-06 27.2 0.5 3.5e-06 26.6 0.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 OWF37178.1 - 0.1 13.2 2.3 47 5.1 0.0 4.0 2 2 1 3 3 3 0 Leucine Rich Repeat Acyl_transf_3 PF01757.22 OWF37179.1 - 3.1e-19 69.2 37.1 4.9e-19 68.6 37.1 1.3 1 0 0 1 1 1 1 Acyltransferase family DSBA PF01323.20 OWF37180.1 - 1.3e-39 136.0 0.0 1.5e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain COR PF16095.5 OWF37181.1 - 2.5e-11 43.8 0.1 5.2e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF37181.1 - 3e-08 33.9 0.0 0.00011 22.4 0.0 2.8 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF37181.1 - 0.0069 16.0 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_18 PF13238.6 OWF37181.1 - 0.017 15.7 0.0 0.068 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OWF37181.1 - 0.017 15.5 0.0 0.048 14.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank PF00023.30 OWF37181.1 - 0.021 15.3 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat RNA_helicase PF00910.22 OWF37181.1 - 0.033 14.6 0.1 0.43 11.0 0.0 2.8 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 OWF37181.1 - 0.094 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OWF37181.1 - 0.098 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OWF37181.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 OWF37181.1 - 0.14 12.8 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) AAA_24 PF13479.6 OWF37181.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank_3 PF13606.6 OWF37181.1 - 0.14 12.8 0.0 1.3 9.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Death PF00531.22 OWF37182.1 - 7.3e-12 45.3 0.3 0.0001 22.4 0.0 2.3 2 0 0 2 2 2 2 Death domain KRTDAP PF15200.6 OWF37182.1 - 0.059 13.2 0.1 0.32 10.8 0.0 2.1 2 1 0 2 2 2 0 Keratinocyte differentiation-associated Ski_Sno PF02437.17 OWF37183.1 - 4.3e-43 145.5 2.4 1.2e-42 144.0 2.4 1.8 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 OWF37183.1 - 2.1e-38 130.4 3.3 4.9e-38 129.3 3.3 1.7 1 0 0 1 1 1 1 c-SKI Smad4 binding domain UBZ_FAAP20 PF15750.5 OWF37184.1 - 8.3e-14 51.3 1.8 2.2e-13 49.9 1.8 1.8 1 0 0 1 1 1 1 Ubiquitin-binding zinc-finger Rad50_zn_hook PF04423.14 OWF37184.1 - 0.011 15.5 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Acatn PF13000.7 OWF37185.1 - 2.8e-120 402.4 19.9 2.4e-70 237.6 11.5 3.0 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DUF2614 PF11023.8 OWF37185.1 - 0.36 10.9 1.6 3.3 7.8 0.4 2.7 1 1 1 2 2 2 0 Zinc-ribbon containing domain 7tm_2 PF00002.24 OWF37186.1 - 0.015 14.6 8.8 0.019 14.3 8.8 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF2567 PF10821.8 OWF37187.1 - 0.064 13.3 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) SPC25 PF06703.11 OWF37187.1 - 0.21 11.3 3.3 0.47 10.2 3.3 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Death PF00531.22 OWF37188.1 - 4.1e-12 46.1 0.2 9.7e-12 44.9 0.2 1.6 1 0 0 1 1 1 1 Death domain RHIM PF12721.7 OWF37188.1 - 0.015 15.8 2.3 0.035 14.6 2.3 1.6 1 0 0 1 1 1 0 RIP homotypic interaction motif DUF148 PF02520.17 OWF37188.1 - 1.8 8.7 6.0 1.3 9.2 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 Lipase_GDSL_2 PF13472.6 OWF37189.1 - 7.6e-12 46.0 0.0 9.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF37189.1 - 3.6e-07 30.4 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NUDIX PF00293.28 OWF37190.1 - 1.5e-08 34.7 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Elong_Iki1 PF10483.9 OWF37191.1 - 1e-21 77.7 3.2 2.7e-11 43.5 0.3 2.1 1 1 1 2 2 2 2 Elongator subunit Iki1 DUF4923 PF16270.5 OWF37191.1 - 0.077 12.8 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Lipocalin-like domain (DUF4923) UBX PF00789.20 OWF37192.1 - 2e-07 31.1 0.1 2.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 UBX domain DEAD PF00270.29 OWF37193.1 - 7.6e-28 97.5 0.8 1.7e-27 96.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF37193.1 - 4.4e-24 85.0 0.0 1.1e-23 83.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF37193.1 - 4e-06 26.9 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OWF37193.1 - 0.0028 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaJ PF00226.31 OWF37194.1 - 1.8e-12 47.2 0.6 1.8e-12 47.2 0.6 2.3 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 OWF37194.1 - 0.0083 16.1 0.0 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin DUF1198 PF06711.11 OWF37194.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) OAD_gamma PF04277.13 OWF37194.1 - 0.17 12.5 0.0 0.36 11.5 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain EF-hand_7 PF13499.6 OWF37196.1 - 4.5e-28 97.5 1.6 2.4e-15 56.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF37196.1 - 2.8e-26 89.0 7.9 3.9e-08 32.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF37196.1 - 2.5e-22 76.9 3.7 5.8e-08 32.0 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF37196.1 - 1.7e-17 63.0 10.0 1.1e-08 34.8 0.3 4.1 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF37196.1 - 2.6e-12 45.7 10.2 6.7e-05 22.2 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.6 OWF37196.1 - 4e-10 39.9 0.0 0.001 19.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37196.1 - 2.1e-05 24.4 1.7 0.051 13.5 0.3 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF3349 PF11829.8 OWF37196.1 - 0.00077 20.2 0.7 0.75 10.6 0.0 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) Caleosin PF05042.13 OWF37196.1 - 0.0023 17.9 0.0 1.7 8.5 0.0 2.6 2 1 1 3 3 3 2 Caleosin related protein EFhand_Ca_insen PF08726.10 OWF37196.1 - 0.0023 18.0 0.1 0.0083 16.2 0.0 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 OWF37196.1 - 0.023 14.7 0.3 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0154) Phage_TAC_12 PF12363.8 OWF37196.1 - 0.095 13.1 1.3 2.5 8.6 0.2 2.4 1 1 2 3 3 3 0 Phage tail assembly chaperone protein, TAC SUB1_ProdP9 PF18213.1 OWF37196.1 - 0.73 9.7 4.4 1.5 8.7 0.3 2.8 1 1 2 3 3 3 0 SUB1 protease Prodomain ProdP9 DED PF01335.21 OWF37196.1 - 2.2 8.6 5.6 8.3 6.8 0.1 2.7 2 1 0 2 2 2 0 Death effector domain EF-hand_1 PF00036.32 OWF37197.1 - 2.2e-38 127.0 18.7 1.4e-09 36.8 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37197.1 - 2.9e-33 114.1 8.2 5.6e-17 62.0 2.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37197.1 - 3.9e-29 98.1 12.8 4.2e-09 35.6 0.3 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37197.1 - 9.6e-28 95.8 18.1 4.9e-15 55.1 3.4 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF37197.1 - 1.6e-27 93.7 17.6 8.9e-08 31.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37197.1 - 4.7e-15 55.7 0.5 2e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37197.1 - 1.4e-10 41.1 4.7 8.4e-05 22.5 0.5 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37197.1 - 5.1e-09 36.4 1.5 0.00028 21.2 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF37197.1 - 2.9e-07 31.3 0.0 2.2e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 OWF37197.1 - 7.2e-05 22.8 0.6 0.33 10.8 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein UPF0154 PF03672.13 OWF37197.1 - 0.00015 21.7 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF37197.1 - 0.00034 20.7 5.7 0.57 10.4 0.7 3.4 1 1 3 4 4 4 3 Dockerin type I domain EF-hand_14 PF17959.1 OWF37197.1 - 0.0025 18.1 0.2 0.76 10.2 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 OWF37197.1 - 0.026 13.1 0.0 0.029 12.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF4497 PF14924.6 OWF37197.1 - 0.037 14.5 0.0 7.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) FGAR-AT_linker PF18072.1 OWF37197.1 - 0.069 13.7 0.1 7.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Staphylokinase PF02821.16 OWF37197.1 - 0.083 13.3 0.2 0.52 10.8 0.1 2.2 1 1 2 3 3 3 0 Staphylokinase/Streptokinase family Fe_hyd_lg_C PF02906.14 OWF37197.1 - 0.091 12.4 0.5 0.35 10.5 0.1 1.9 1 1 1 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain VCBS PF13517.6 OWF37197.1 - 2.7 8.7 9.6 0.67 10.6 2.6 2.8 1 1 2 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_7 PF13499.6 OWF37198.1 - 9.4e-24 83.7 4.2 8.9e-12 45.3 2.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF37198.1 - 2.3e-23 80.0 10.1 7.5e-07 28.3 1.0 4.7 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 OWF37198.1 - 2.9e-18 64.2 8.9 7.4e-06 25.5 0.1 4.5 3 1 2 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OWF37198.1 - 7.8e-15 54.5 7.8 3.2e-09 36.5 0.6 4.5 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF37198.1 - 5.4e-10 38.3 8.9 9.5e-05 21.7 0.7 4.0 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OWF37198.1 - 4.5e-09 36.5 0.2 0.00015 22.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37198.1 - 1e-05 25.4 1.4 0.00012 21.9 0.3 2.3 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OWF37198.1 - 0.014 16.3 0.1 0.047 14.6 0.1 1.7 1 1 1 2 2 2 0 EF-hand domain Sec34 PF04136.15 OWF37198.1 - 0.017 15.0 0.7 0.022 14.6 0.1 1.6 2 0 0 2 2 2 0 Sec34-like family EF-hand_14 PF17959.1 OWF37198.1 - 0.037 14.4 0.1 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 OWF37199.1 - 2.1e-30 102.0 11.9 2.5e-07 29.7 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37199.1 - 2.2e-29 101.7 4.9 6e-16 58.7 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37199.1 - 6.2e-23 78.7 10.3 2.7e-07 30.0 1.3 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37199.1 - 7.7e-21 73.7 10.2 1.7e-12 47.0 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF37199.1 - 3.1e-15 56.2 0.4 2.1e-09 37.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF37199.1 - 1.8e-13 49.3 11.6 0.00015 21.1 3.5 4.1 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 OWF37199.1 - 1e-06 29.1 1.0 0.0088 16.4 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF37199.1 - 3.5e-05 23.9 2.0 0.00037 20.6 0.0 2.6 1 1 1 2 2 2 1 Dockerin type I domain EF-hand_11 PF08976.11 OWF37199.1 - 3.8e-05 24.5 0.1 0.00067 20.5 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OWF37199.1 - 0.00017 21.5 6.8 0.088 12.8 0.2 3.0 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF37199.1 - 0.0023 17.9 0.0 0.0078 16.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 OWF37199.1 - 0.0033 18.2 0.3 2.7 8.8 0.0 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RuvA_C PF07499.13 OWF37199.1 - 0.012 16.1 0.3 0.026 15.0 0.3 1.6 1 0 0 1 1 1 0 RuvA, C-terminal domain Caleosin PF05042.13 OWF37199.1 - 0.015 15.2 0.4 3.4 7.6 0.0 2.8 2 1 1 3 3 3 0 Caleosin related protein DUF1840 PF08895.11 OWF37199.1 - 0.03 14.7 0.5 0.27 11.6 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) GPHH PF16905.5 OWF37199.1 - 0.047 13.5 0.0 70 3.3 0.0 3.8 4 0 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated Mu-like_Pro PF10123.9 OWF37199.1 - 0.057 13.0 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein EFhand_Ca_insen PF08726.10 OWF37199.1 - 0.059 13.5 0.2 0.46 10.6 0.1 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand DUF853 PF05872.12 OWF37199.1 - 0.21 10.1 0.6 1.5 7.3 0.1 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_10 PF14788.6 OWF37199.1 - 0.41 10.5 3.4 2.6 8.0 0.2 3.0 2 1 1 3 3 3 0 EF hand EF-hand_7 PF13499.6 OWF37200.1 - 1.4e-34 118.3 1.4 3.4e-18 65.8 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF37200.1 - 9.3e-32 106.2 2.3 5.5e-08 31.8 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF37200.1 - 2.7e-25 88.0 7.1 8.2e-14 51.2 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37200.1 - 6.7e-25 84.9 1.8 5.6e-06 25.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37200.1 - 9.7e-21 72.3 2.8 3.4e-05 23.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37200.1 - 7.9e-14 51.7 0.1 1.4e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37200.1 - 4.4e-08 33.4 0.8 0.002 18.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF37200.1 - 4.7e-07 29.7 1.4 0.0068 16.3 0.1 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 OWF37200.1 - 0.00027 20.9 0.0 0.044 13.7 0.0 2.2 1 1 0 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.13 OWF37200.1 - 0.00096 19.1 0.4 14 5.5 0.0 3.6 1 1 3 4 4 4 0 Caleosin related protein EF-hand_11 PF08976.11 OWF37200.1 - 0.0033 18.3 0.1 0.0077 17.1 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 OWF37200.1 - 0.004 17.3 0.9 0.36 11.0 0.0 2.7 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_10 PF14788.6 OWF37200.1 - 0.014 15.3 2.5 9 6.2 0.0 3.6 2 2 2 4 4 4 0 EF hand EF-hand_14 PF17959.1 OWF37200.1 - 0.022 15.1 0.1 0.06 13.7 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain LXG PF04740.12 OWF37200.1 - 0.054 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF3349 PF11829.8 OWF37200.1 - 0.12 13.1 0.1 2.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) UPF0154 PF03672.13 OWF37200.1 - 0.23 11.5 0.6 2 8.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) EF-hand_1 PF00036.32 OWF37201.1 - 4.9e-34 113.3 22.4 9e-09 34.3 2.2 4.6 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.6 OWF37201.1 - 2.2e-33 114.5 10.2 9.4e-17 61.2 3.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37201.1 - 7e-27 91.0 11.4 3.9e-09 35.7 0.8 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37201.1 - 3.3e-25 87.7 17.0 2.7e-12 46.3 2.2 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF37201.1 - 1.4e-21 75.0 17.7 2e-06 27.0 1.0 5.1 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 OWF37201.1 - 5.4e-11 42.7 0.1 0.00034 20.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37201.1 - 9.7e-09 35.6 2.2 9.3e-05 22.7 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF37201.1 - 9.2e-05 22.3 6.1 0.097 12.6 1.7 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OWF37201.1 - 0.00037 20.6 3.7 0.67 10.2 3.3 3.0 1 1 1 2 2 2 2 Dockerin type I domain UPF0154 PF03672.13 OWF37201.1 - 0.0046 16.9 1.2 0.038 14.0 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OWF37201.1 - 0.064 14.1 0.1 0.86 10.5 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 OWF37201.1 - 0.078 13.3 0.6 15 6.1 0.2 2.6 1 1 2 3 3 3 0 EF-hand domain DUF1296 PF06972.11 OWF37201.1 - 0.089 12.9 0.7 20 5.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) EF-hand_10 PF14788.6 OWF37201.1 - 0.14 12.0 0.5 0.14 12.0 0.5 3.1 1 1 1 3 3 3 0 EF hand EF-hand_1 PF00036.32 OWF37202.1 - 1.1e-21 74.7 5.8 5.8e-08 31.7 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF37202.1 - 2.6e-19 69.4 0.9 2.8e-14 53.3 1.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37202.1 - 3.8e-18 65.1 5.8 5e-11 42.3 1.3 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF37202.1 - 3.9e-15 54.4 1.1 2.7e-06 26.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.6 OWF37202.1 - 2.1e-08 34.3 0.1 0.0054 17.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37202.1 - 2.4e-07 30.7 0.0 0.0086 16.0 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OWF37202.1 - 0.00011 21.5 3.9 0.34 10.5 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_11 PF08976.11 OWF37202.1 - 0.00055 20.8 0.1 0.0011 19.9 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain UPF0154 PF03672.13 OWF37202.1 - 0.00067 19.6 0.2 1.5 8.9 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) Acyl-ACP_TE PF01643.17 OWF37202.1 - 0.017 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase DED PF01335.21 OWF37202.1 - 0.1 12.9 0.0 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 Death effector domain EF-hand_1 PF00036.32 OWF37203.1 - 9.7e-30 99.9 8.9 1.2e-09 37.0 0.1 4.7 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF37203.1 - 9.4e-29 99.7 0.5 1.4e-16 60.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37203.1 - 6.5e-27 91.1 2.1 6.6e-09 35.0 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF37203.1 - 3.6e-20 71.6 7.1 5.2e-12 45.4 0.4 4.0 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF37203.1 - 1.6e-17 62.2 5.8 2.8e-06 26.6 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OWF37203.1 - 8.5e-17 61.2 0.0 3e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37203.1 - 3.8e-07 30.0 0.4 0.00013 21.8 0.0 2.6 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 OWF37203.1 - 1.4e-05 25.1 0.1 5.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OWF37203.1 - 0.0053 16.9 0.6 0.042 14.1 0.1 2.5 2 1 1 3 3 3 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OWF37203.1 - 0.0072 16.6 0.0 0.031 14.6 0.0 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF37203.1 - 0.0093 16.0 0.0 5.7 7.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 OWF37203.1 - 0.014 15.3 0.1 8.2 6.3 0.0 2.6 2 1 0 2 2 2 0 Caleosin related protein DUF3349 PF11829.8 OWF37203.1 - 0.015 16.1 0.0 0.83 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_11 PF08976.11 OWF37203.1 - 0.049 14.5 0.0 0.12 13.2 0.0 1.6 1 1 1 2 2 2 0 EF-hand domain DUF853 PF05872.12 OWF37203.1 - 0.083 11.5 0.0 5.4 5.5 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) FGAR-AT_linker PF18072.1 OWF37203.1 - 0.088 13.4 0.2 3.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Phage_tail_S PF05069.13 OWF37203.1 - 0.18 11.6 0.0 12 5.7 0.0 2.1 1 1 1 2 2 2 0 Phage virion morphogenesis family PPR_1 PF12854.7 OWF37203.1 - 0.39 10.5 1.5 8 6.3 0.4 2.4 2 0 0 2 2 2 0 PPR repeat EF-hand_1 PF00036.32 OWF37204.1 - 1.6e-37 124.2 13.3 1e-09 37.2 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37204.1 - 1.2e-33 115.4 4.0 7.7e-18 64.7 2.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37204.1 - 6.7e-26 88.0 7.5 2.5e-08 33.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37204.1 - 1.3e-25 89.0 11.6 8.4e-16 57.6 1.9 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF37204.1 - 1.1e-24 84.8 11.2 1.6e-06 27.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37204.1 - 1.9e-13 50.6 0.1 3.3e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37204.1 - 9.7e-11 41.5 2.0 0.00015 21.7 1.2 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37204.1 - 1.2e-06 28.8 0.0 0.0073 16.6 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF37204.1 - 1.1e-05 25.3 0.4 0.0061 16.5 0.0 2.6 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF37204.1 - 1.4e-05 25.2 7.4 0.0076 16.4 1.5 3.3 1 1 3 4 4 4 4 Dockerin type I domain EF-hand_11 PF08976.11 OWF37204.1 - 4.2e-05 24.4 0.0 0.0012 19.7 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain DUF1103 PF06513.11 OWF37204.1 - 0.0015 18.2 2.1 0.0023 17.6 2.1 1.4 1 1 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF853 PF05872.12 OWF37204.1 - 0.016 13.9 0.1 0.068 11.7 0.1 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) SurA_N_2 PF13623.6 OWF37204.1 - 0.017 15.0 0.4 0.031 14.1 0.3 1.6 1 1 0 1 1 1 0 SurA N-terminal domain Caleosin PF05042.13 OWF37204.1 - 0.041 13.8 0.1 5.9 6.8 0.0 3.0 1 1 3 4 4 4 0 Caleosin related protein SurA_N_3 PF13624.6 OWF37204.1 - 0.043 13.6 0.4 0.071 12.9 0.3 1.5 1 1 0 1 1 1 0 SurA N-terminal domain VCBS PF13517.6 OWF37204.1 - 1 10.0 7.7 19 5.9 0.6 3.5 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.32 OWF37205.1 - 4.8e-41 135.3 10.3 1.3e-09 37.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37205.1 - 7.8e-36 122.4 3.1 9e-18 64.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37205.1 - 3.2e-30 101.4 6.1 4.4e-09 35.5 0.2 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37205.1 - 8.8e-30 102.3 9.7 1.1e-13 50.8 0.6 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF37205.1 - 7.8e-27 91.6 7.5 1.7e-06 27.2 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37205.1 - 8.3e-15 54.9 0.0 5.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37205.1 - 2.8e-10 40.1 0.4 0.00011 22.1 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF37205.1 - 1.2e-08 35.2 0.2 0.0056 17.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF37205.1 - 1.3e-06 29.2 0.0 0.0021 18.9 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OWF37205.1 - 1.8e-06 28.0 3.4 0.0018 18.5 0.2 2.9 1 1 2 3 3 3 3 Dockerin type I domain UPF0154 PF03672.13 OWF37205.1 - 0.00016 21.7 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.11 OWF37205.1 - 0.00028 20.6 1.1 0.00031 20.4 1.1 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.16 OWF37205.1 - 0.00083 19.7 0.5 0.34 11.2 0.3 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 OWF37205.1 - 0.004 15.8 0.0 0.0056 15.3 0.0 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5580) Caleosin PF05042.13 OWF37205.1 - 0.015 15.2 0.5 0.83 9.6 0.2 3.3 1 1 1 2 2 2 0 Caleosin related protein dCache_2 PF08269.11 OWF37205.1 - 0.027 13.7 0.1 1.6 7.8 0.1 2.2 1 1 0 1 1 1 0 Cache domain SapB_1 PF05184.15 OWF37205.1 - 0.42 10.7 1.9 27 4.9 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 SUB1_ProdP9 PF18213.1 OWF37205.1 - 0.62 9.9 2.9 2.1 8.3 0.3 2.6 1 1 2 3 3 3 0 SUB1 protease Prodomain ProdP9 HSP70 PF00012.20 OWF37207.1 - 2.2e-10 39.4 0.1 2.6e-06 25.9 0.0 2.7 2 2 0 2 2 2 2 Hsp70 protein HSP70 PF00012.20 OWF37208.1 - 1.6e-09 36.5 0.3 4.2e-06 25.2 0.0 2.5 2 1 0 2 2 2 2 Hsp70 protein Hydantoinase_A PF01968.18 OWF37208.1 - 0.052 12.8 0.3 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 OWF37209.1 - 0.031 12.5 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein HSP70 PF00012.20 OWF37210.1 - 0.027 12.6 0.0 0.069 11.3 0.0 1.5 2 0 0 2 2 2 0 Hsp70 protein NPCBM PF08305.11 OWF37210.1 - 0.048 13.8 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 NPCBM/NEW2 domain DMT_YdcZ PF04657.13 OWF37211.1 - 0.014 15.6 0.4 0.036 14.3 0.4 1.6 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ ECSCR PF15820.5 OWF37211.1 - 0.062 13.1 1.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator 7tm_1 PF00001.21 OWF37211.1 - 0.59 9.4 5.4 2.8 7.2 0.6 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) CTD PF12815.7 OWF37212.1 - 2.4e-10 40.8 0.0 0.0028 18.2 0.0 4.4 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 PMG PF05287.12 OWF37212.1 - 8.4e-05 22.7 0.0 0.77 9.8 0.0 3.6 1 1 2 3 3 3 2 PMG protein HET-s_218-289 PF11558.8 OWF37212.1 - 0.0085 16.1 1.9 31 4.7 0.1 5.8 5 3 0 6 6 6 0 Het-s 218-289 BfiI_DBD PF18243.1 OWF37212.1 - 0.17 11.5 3.9 12 5.5 0.0 4.8 3 1 1 6 6 6 0 Metal-independent restriction enzyme BfiI DNA binding domain Hexapep_2 PF14602.6 OWF37212.1 - 0.23 11.2 8.1 44 3.9 0.0 5.9 5 2 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase NADHdeh_related PF10125.9 OWF37212.1 - 0.26 10.6 11.7 30 3.9 0.1 6.2 2 2 6 8 8 8 0 NADH dehydrogenase I, subunit N related protein Glycos_trans_3N PF02885.17 OWF37212.1 - 0.26 11.1 0.1 56 3.7 0.0 3.1 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Suv3_C_1 PF18147.1 OWF37212.1 - 0.32 10.9 4.0 18 5.3 0.1 5.0 6 0 0 6 6 6 0 Suv3 C-terminal domain 1 CTD PF12815.7 OWF37213.1 - 5.8e-05 23.6 0.0 0.0059 17.2 0.0 2.5 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 WD40_3 PF15911.5 OWF37213.1 - 0.0017 18.3 0.1 17 5.5 0.0 3.1 2 1 1 3 3 3 2 WD domain, G-beta repeat NADHdeh_related PF10125.9 OWF37213.1 - 0.34 10.2 7.8 27 4.0 0.1 4.8 1 1 4 5 5 5 0 NADH dehydrogenase I, subunit N related protein BfiI_DBD PF18243.1 OWF37213.1 - 0.59 9.7 2.4 11 5.6 0.1 3.2 1 1 3 4 4 4 0 Metal-independent restriction enzyme BfiI DNA binding domain DUF4605 PF15378.6 OWF37213.1 - 0.66 9.9 4.8 40 4.2 0.0 4.1 1 1 3 5 5 5 0 Domain of unknown function (DUF4605) Erythrovirus_X PF06795.11 OWF37215.1 - 9.4e-11 41.9 9.6 14 6.1 0.0 11.4 2 2 12 14 14 14 1 Erythrovirus X protein DUF3198 PF11433.8 OWF37215.1 - 5.9e-07 29.3 17.2 1.3e+02 2.6 0.0 14.7 3 3 17 24 24 24 0 Protein of unknown function (DUF3198) AAA_19 PF13245.6 OWF37215.1 - 9.6e-06 26.0 16.8 15 5.9 0.1 8.4 1 1 6 8 8 8 1 AAA domain Gemini_C4 PF01492.17 OWF37215.1 - 0.00019 21.3 10.6 1.4e+02 2.4 0.0 10.1 10 2 2 12 12 12 0 Geminivirus C4 protein APG17 PF04108.12 OWF37215.1 - 0.068 12.3 0.3 26 3.8 0.1 3.6 1 1 3 4 4 4 0 Autophagy protein Apg17 HTH_26 PF13443.6 OWF37215.1 - 0.074 13.5 75.7 56 4.3 0.0 23.4 12 7 15 28 28 28 0 Cro/C1-type HTH DNA-binding domain Dynein_C PF18199.1 OWF37215.1 - 0.23 10.6 0.1 53 2.9 0.0 3.7 3 1 1 4 4 4 0 Dynein heavy chain C-terminal domain Mito_carr PF00153.27 OWF37216.1 - 2.7e-62 206.7 2.2 4e-23 81.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane_3 PF12698.7 OWF37217.1 - 0.22 10.6 0.1 0.28 10.2 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Presenilin PF01080.17 OWF37217.1 - 0.76 8.5 2.3 0.91 8.2 2.3 1.2 1 0 0 1 1 1 0 Presenilin TMF_DNA_bd PF12329.8 OWF37217.1 - 7.9 6.6 12.0 0.11 12.5 2.6 2.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SNF2_N PF00176.23 OWF37219.1 - 5.5e-77 258.9 0.1 1e-76 257.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OWF37219.1 - 4e-42 142.8 2.6 4e-42 142.8 2.6 2.8 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 OWF37219.1 - 2.7e-29 102.1 0.9 2.7e-29 102.1 0.9 3.0 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 OWF37219.1 - 4.9e-15 55.8 0.0 2.6e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF37219.1 - 4e-10 40.0 0.0 2.2e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF37219.1 - 1.6e-06 28.0 0.0 7.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 OWF37219.1 - 7.1e-06 26.1 1.8 0.06 13.5 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain DBINO PF13892.6 OWF37219.1 - 2.3e-05 24.8 0.1 2.3e-05 24.8 0.1 4.0 4 0 0 4 4 4 1 DNA-binding domain HDA2-3 PF11496.8 OWF37219.1 - 0.00028 20.1 0.0 0.00061 19.1 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CDH1_2_SANT_HL1 PF18375.1 OWF37219.1 - 0.19 12.4 3.8 13 6.5 0.1 3.0 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 LrgB PF04172.16 OWF37220.1 - 0.13 11.8 3.1 0.2 11.1 3.1 1.2 1 0 0 1 1 1 0 LrgB-like family Pkinase_Tyr PF07714.17 OWF37221.1 - 5.8e-36 124.1 0.0 8.6e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF37221.1 - 2.4e-19 69.7 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OWF37221.1 - 2.5e-17 62.7 15.8 1.1e-08 35.1 2.3 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF37221.1 - 2.5e-17 63.0 4.6 1.2e-10 41.6 0.5 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF37221.1 - 1.1e-16 61.2 2.3 2.2e-09 37.8 0.9 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF37221.1 - 2.1e-16 59.5 4.8 0.00028 21.2 2.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OWF37221.1 - 2.2e-14 52.1 5.6 0.00026 21.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat COR PF16095.5 OWF37223.1 - 2e-17 63.7 0.4 1.3e-16 61.0 0.2 2.4 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF37223.1 - 2.4e-14 53.6 0.3 5.9e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF37223.1 - 1.5e-06 28.0 0.6 0.018 14.6 0.2 2.7 2 0 0 2 2 2 2 Ras family RsgA_GTPase PF03193.16 OWF37223.1 - 6.2e-05 23.0 2.3 0.00046 20.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Death PF00531.22 OWF37223.1 - 0.00032 20.8 0.0 0.00098 19.2 0.0 1.8 1 0 0 1 1 1 1 Death domain MMR_HSR1 PF01926.23 OWF37223.1 - 0.0013 18.8 0.1 0.0038 17.3 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OWF37223.1 - 0.0041 17.5 0.0 0.0081 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF37223.1 - 0.0053 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 OWF37223.1 - 0.0091 15.2 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 OWF37223.1 - 0.011 16.3 0.1 0.031 14.8 0.1 1.8 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 OWF37223.1 - 0.015 14.7 0.3 0.11 12.0 0.0 2.4 2 1 1 3 3 3 0 ADP-ribosylation factor family AAA_18 PF13238.6 OWF37223.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase-cat_bd PF12156.8 OWF37223.1 - 0.086 13.6 0.6 0.23 12.2 0.6 1.7 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase FeoB_Cyto PF17910.1 OWF37223.1 - 0.13 12.8 0.2 12 6.5 0.0 3.2 2 1 0 2 2 2 0 FeoB cytosolic helical domain AMP-binding PF00501.28 OWF37224.1 - 4e-47 160.8 0.0 5.9e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 OWF37224.1 - 2e-37 126.7 7.2 5.2e-08 33.2 0.0 9.4 9 0 0 9 9 9 8 PQQ-like domain PQQ PF01011.21 OWF37224.1 - 5.9e-33 111.2 7.7 0.0002 21.1 0.2 8.6 8 0 0 8 8 8 7 PQQ enzyme repeat PQQ_2 PF13360.6 OWF37224.1 - 3.4e-24 85.7 0.0 1.9e-12 47.3 0.0 3.9 2 1 1 3 3 3 3 PQQ-like domain AMP-binding_C PF13193.6 OWF37224.1 - 2.9e-06 28.2 0.0 7.7e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 OWF37224.1 - 0.0002 21.6 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site ANAPC10 PF03256.16 OWF37225.1 - 9.8e-75 250.3 0.0 1.1e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 OWF37225.1 - 0.00014 22.1 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 PITH domain F5_F8_type_C PF00754.25 OWF37225.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain RmlD_sub_bind PF04321.17 OWF37226.1 - 4.8e-61 206.4 0.0 5.5e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OWF37226.1 - 1.7e-24 86.6 0.0 2.1e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OWF37226.1 - 3.3e-13 49.4 0.4 1.3e-10 40.9 0.4 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OWF37226.1 - 9.1e-13 48.3 0.0 4.2e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OWF37226.1 - 1.4e-08 34.2 0.0 3.2e-06 26.5 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 OWF37226.1 - 2.6e-06 26.6 0.1 1.1e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 OWF37226.1 - 0.047 13.8 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GTP_EFTU_D3 PF03143.17 OWF37226.1 - 0.086 13.2 0.0 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain AP_endonuc_2 PF01261.24 OWF37226.1 - 0.1 12.0 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Ank_2 PF12796.7 OWF37227.1 - 5.5e-27 94.2 0.0 9.1e-12 45.4 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 OWF37227.1 - 4.3e-18 64.9 0.0 0.0018 18.6 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OWF37227.1 - 3.8e-17 60.6 0.4 0.0038 17.6 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 OWF37227.1 - 1.9e-15 57.0 0.4 2.4e-05 24.8 0.0 6.3 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37227.1 - 2e-15 56.6 1.7 2.4e-06 27.7 0.0 6.6 4 2 3 7 7 7 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF37227.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 SOCS box Trp_dioxygenase PF03301.13 OWF37228.1 - 3.1e-138 460.8 1.9 4e-138 460.5 1.9 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase HSP70 PF00012.20 OWF37229.1 - 1.7e-12 46.4 0.9 1.8e-11 43.0 0.9 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF37229.1 - 0.0039 16.1 1.2 0.98 8.2 0.1 2.5 3 0 0 3 3 3 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 OWF37229.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.25 OWF37229.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Sulfate_transp PF00916.20 OWF37231.1 - 5.2e-117 390.8 22.5 6.7e-117 390.4 22.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OWF37231.1 - 2.7e-22 78.6 0.1 5.3e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 STAS domain Herpes_LMP1 PF05297.11 OWF37231.1 - 0.22 10.7 8.2 0.49 9.5 8.2 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ank_2 PF12796.7 OWF37232.1 - 5.8e-49 164.6 6.1 1.4e-12 48.0 0.2 6.6 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF37232.1 - 1.9e-41 135.3 13.9 2.6e-06 27.3 0.0 10.6 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 OWF37232.1 - 1.6e-39 132.6 14.1 2.4e-05 24.5 0.1 9.8 9 1 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 OWF37232.1 - 8.2e-38 128.3 8.6 1.3e-08 35.2 0.1 9.0 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37232.1 - 1e-32 111.7 13.8 1.3e-06 28.6 0.1 8.4 2 1 7 9 9 9 8 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF37232.1 - 3.8e-08 33.6 2.6 1.1e-07 32.0 2.6 1.9 1 0 0 1 1 1 1 SOCS box DUF2520 PF10728.9 OWF37232.1 - 0.026 14.3 0.2 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) LRR_8 PF13855.6 OWF37233.1 - 4.8e-25 87.1 12.0 3.4e-12 45.9 0.3 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF37233.1 - 8.4e-13 48.3 14.2 4.4e-05 23.7 0.9 4.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 OWF37233.1 - 1.1e-09 38.7 2.7 3.6e-09 37.1 0.4 2.7 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 OWF37233.1 - 8.6e-08 32.1 0.1 2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.6 OWF37233.1 - 1.6e-05 24.5 0.6 0.0059 16.1 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat ig PF00047.25 OWF37233.1 - 2e-05 24.7 0.5 5.1e-05 23.4 0.5 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 OWF37233.1 - 2e-05 24.6 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF37233.1 - 2.9e-05 24.0 13.3 0.17 12.5 0.6 6.0 3 2 2 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 OWF37233.1 - 0.00016 21.4 12.1 4.7 7.5 0.3 6.4 6 0 0 6 6 6 2 Leucine Rich repeat Ig_2 PF13895.6 OWF37233.1 - 0.0023 18.2 2.0 0.0039 17.5 0.5 2.1 3 0 0 3 3 3 1 Immunoglobulin domain Orthoreo_P10 PF07204.11 OWF37233.1 - 0.0028 17.6 1.2 0.0075 16.2 0.8 1.9 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 LRR_8 PF13855.6 OWF37234.1 - 8.8e-20 70.2 9.2 2.1e-09 37.0 0.0 3.4 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OWF37234.1 - 4.7e-14 52.3 11.0 5.7e-05 23.4 0.4 4.2 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF37234.1 - 1.8e-07 30.7 12.1 0.018 15.5 0.3 5.2 4 2 2 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.6 OWF37234.1 - 9.6e-05 22.3 0.0 0.00019 21.4 0.0 1.5 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 OWF37234.1 - 0.0014 18.6 16.0 0.25 11.5 0.2 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 OWF37234.1 - 0.0044 16.5 0.8 0.9 9.0 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat DUF3884 PF13024.6 OWF37234.1 - 0.13 11.8 0.3 0.56 9.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3884) LRR_8 PF13855.6 OWF37235.1 - 9.1e-24 83.0 11.8 1.2e-12 47.4 0.3 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF37235.1 - 2.2e-13 50.2 12.9 0.00015 22.0 1.6 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 OWF37235.1 - 1.2e-08 35.4 1.2 1.8e-08 34.9 0.4 1.8 2 0 0 2 2 1 1 Immunoglobulin domain I-set PF07679.16 OWF37235.1 - 1.7e-08 34.4 0.1 3.2e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.33 OWF37235.1 - 1.1e-06 28.4 8.4 0.14 12.8 0.5 5.7 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 OWF37235.1 - 1.1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 OWF37235.1 - 2.2e-06 27.8 0.7 4.7e-06 26.7 0.7 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 OWF37235.1 - 8.1e-06 25.4 0.8 0.0032 17.0 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Ig_2 PF13895.6 OWF37235.1 - 9.7e-05 22.6 0.4 0.0003 21.1 0.3 1.9 2 0 0 2 2 2 1 Immunoglobulin domain LRR_6 PF13516.6 OWF37235.1 - 0.0005 19.9 13.7 3.9 7.8 0.3 6.5 6 0 0 6 6 6 2 Leucine Rich repeat V-set PF07686.17 OWF37235.1 - 0.077 13.2 0.6 0.2 11.8 0.6 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain NUT PF12881.7 OWF37235.1 - 0.14 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 NUT protein Peptidase_C14 PF00656.22 OWF37236.1 - 8.6e-19 68.5 0.0 2.9e-17 63.4 0.0 2.4 2 1 0 2 2 2 1 Caspase domain SOG2 PF10428.9 OWF37236.1 - 1.4 8.0 8.0 2.1 7.4 3.8 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Ribosomal_L30 PF00327.20 OWF37238.1 - 2.7e-06 27.2 1.2 7.1e-06 25.8 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e zf-RING_2 PF13639.6 OWF37239.1 - 6.1e-06 26.5 8.3 1.1e-05 25.6 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OWF37239.1 - 0.00022 21.4 7.3 0.00041 20.6 7.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 OWF37239.1 - 0.0021 18.2 9.3 0.036 14.3 9.3 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain DZR PF12773.7 OWF37239.1 - 0.014 15.4 0.3 0.032 14.3 0.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 OWF37239.1 - 0.016 15.3 6.0 0.03 14.4 5.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OWF37239.1 - 0.043 13.8 8.6 0.073 13.0 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF37239.1 - 0.046 13.6 8.3 0.1 12.5 8.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF37239.1 - 0.08 12.8 6.3 0.17 11.8 6.3 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 OWF37239.1 - 0.1 12.7 2.2 0.21 11.7 2.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Di19 PF05605.12 OWF37239.1 - 0.1 12.9 1.2 0.62 10.4 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 OWF37239.1 - 0.19 11.5 4.1 0.49 10.2 4.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger RINGv PF12906.7 OWF37239.1 - 2.1 8.6 8.0 3.8 7.7 8.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 OWF37239.1 - 2.8 7.8 9.8 7.3 6.5 9.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OWF37239.1 - 3.8 7.2 10.3 0.14 11.8 4.4 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OWF37239.1 - 4.7 7.2 8.1 10 6.0 8.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_C PF00137.21 OWF37240.1 - 1.9e-25 89.0 33.3 2.3e-14 53.5 13.8 2.5 3 0 0 3 3 3 2 ATP synthase subunit C DUF5453 PF17534.2 OWF37240.1 - 0.077 13.0 0.2 0.077 13.0 0.2 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5453) Ig_3 PF13927.6 OWF37241.1 - 6e-07 30.0 0.1 1.9e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF37241.1 - 0.0003 20.8 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF37241.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Orthoreo_P10 PF07204.11 OWF37241.1 - 0.0032 17.4 0.5 0.0055 16.6 0.1 1.6 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 Ig_2 PF13895.6 OWF37241.1 - 0.0061 16.9 0.1 0.013 15.9 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Syndecan PF01034.20 OWF37241.1 - 0.081 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain LRR_8 PF13855.6 OWF37242.1 - 1.4e-47 159.3 35.9 3e-15 55.7 0.6 4.4 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OWF37242.1 - 3.2e-16 59.2 12.8 5.3e-06 26.7 0.6 5.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF37242.1 - 5.1e-12 45.9 0.0 2.6e-09 37.1 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 OWF37242.1 - 4e-07 30.0 0.0 8.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF37242.1 - 6.1e-07 29.9 3.0 1.1e-06 29.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.6 OWF37242.1 - 9.1e-07 28.5 2.4 0.055 13.0 0.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 OWF37242.1 - 5.4e-06 26.2 14.2 6.7 7.7 0.0 7.5 7 0 0 7 7 7 2 Leucine Rich Repeat V-set PF07686.17 OWF37242.1 - 0.096 12.9 1.4 6.4 7.0 0.0 3.1 2 1 0 2 2 2 0 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 OWF37242.1 - 0.12 12.6 0.1 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 LRR_6 PF13516.6 OWF37242.1 - 0.44 10.7 12.9 18 5.7 0.0 6.4 7 0 0 7 7 7 0 Leucine Rich repeat LRRNT PF01462.18 OWF37242.1 - 1.1 9.0 8.3 0.16 11.7 1.2 3.0 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain EF-hand_1 PF00036.32 OWF37243.1 - 2.5e-31 104.9 18.8 3.6e-09 35.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37243.1 - 5.3e-28 97.3 10.3 1.7e-13 50.8 3.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37243.1 - 1.6e-25 86.8 12.8 1.9e-09 36.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF37243.1 - 4.4e-24 84.1 15.5 2.7e-12 46.3 1.4 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF37243.1 - 1.6e-13 50.8 0.4 6.4e-06 26.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF37243.1 - 1.6e-11 43.1 18.7 6.5e-06 25.4 0.2 4.6 4 1 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 OWF37243.1 - 6.1e-06 26.1 7.0 0.35 10.8 0.9 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 OWF37243.1 - 0.00089 19.1 2.0 0.083 12.7 0.3 2.2 2 0 0 2 2 2 1 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 OWF37243.1 - 0.00098 19.4 0.8 1.5 9.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Sigma54_CBD PF04963.13 OWF37243.1 - 0.0014 18.5 0.3 0.002 18.0 0.3 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain EF-hand_14 PF17959.1 OWF37243.1 - 0.0021 18.4 1.7 0.67 10.3 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OWF37243.1 - 0.0054 16.9 0.7 0.35 11.1 0.1 2.7 2 1 1 3 3 3 1 Dockerin type I domain DUF3349 PF11829.8 OWF37243.1 - 0.0083 16.9 2.6 9.4 7.1 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) SurA_N_2 PF13623.6 OWF37243.1 - 0.013 15.3 1.5 1.9 8.3 0.1 2.5 1 1 1 2 2 2 0 SurA N-terminal domain TerB PF05099.13 OWF37243.1 - 0.036 14.0 1.1 0.3 11.0 0.1 2.4 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF853 PF05872.12 OWF37243.1 - 0.047 12.3 0.5 2.7 6.5 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_11 PF08976.11 OWF37243.1 - 0.054 14.4 0.3 11 7.0 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain SRI PF08236.11 OWF37243.1 - 0.06 13.5 3.3 1.3 9.3 0.9 3.1 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain SUB1_ProdP9 PF18213.1 OWF37243.1 - 0.062 13.2 1.1 0.094 12.6 0.4 1.7 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 DUF3008 PF11450.8 OWF37243.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) CLN5 PF15014.6 OWF37244.1 - 9.8e-139 462.2 4.0 1.2e-138 461.9 4.0 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 COMM_domain PF07258.14 OWF37245.1 - 1.1e-18 67.1 0.1 1.3e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 COMM domain Cadherin PF00028.17 OWF37246.1 - 2.5e-94 309.9 19.3 1.3e-17 64.0 0.1 8.3 8 0 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 OWF37246.1 - 4e-08 33.0 0.0 1.9e-05 24.4 0.0 3.9 3 0 0 3 3 3 1 Cadherin-like Consortin_C PF15281.6 OWF37246.1 - 0.084 12.9 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Consortin C-terminus EphA2_TM PF14575.6 OWF37246.1 - 0.089 13.7 0.0 0.35 11.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OWF37246.1 - 0.19 12.0 2.3 0.16 12.3 0.2 2.0 2 0 0 2 2 2 0 Orf78 (ac78) PIRT PF15099.6 OWF37246.1 - 0.31 10.6 1.2 6.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family TMEM154 PF15102.6 OWF37246.1 - 2.5 8.0 6.4 0.17 11.8 0.5 2.1 2 0 0 2 2 2 0 TMEM154 protein family SNF PF00209.18 OWF37247.1 - 8.5e-115 384.4 35.6 1.1e-114 384.0 35.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3935 PF13071.6 OWF37247.1 - 0.18 12.4 4.3 0.079 13.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) SNF PF00209.18 OWF37248.1 - 4.6e-184 612.9 42.8 6.9e-127 424.3 22.6 2.2 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Adeno_E3_CR2 PF02439.15 OWF37249.1 - 0.0025 17.5 0.4 0.0066 16.2 0.4 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Cytomega_TRL10 PF06084.11 OWF37249.1 - 0.017 15.2 0.4 0.017 15.2 0.4 2.6 3 1 0 3 3 3 0 Cytomegalovirus TRL10 protein DP-EP PF08985.11 OWF37249.1 - 0.08 13.1 1.5 0.15 12.2 0.6 2.0 2 1 0 2 2 2 0 DP-EP family Syndecan PF01034.20 OWF37249.1 - 0.082 12.8 1.2 0.25 11.3 1.2 1.8 1 0 0 1 1 1 0 Syndecan domain MeaB PF03308.16 OWF37250.1 - 1.1e-91 306.5 0.1 1.4e-91 306.2 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OWF37250.1 - 3.3e-08 33.3 0.0 3.4e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OWF37250.1 - 0.00029 20.7 0.0 0.00084 19.2 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OWF37250.1 - 0.00037 20.3 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OWF37250.1 - 0.0048 16.6 0.1 0.015 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 OWF37250.1 - 0.0085 15.4 0.0 0.012 14.9 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain MMR_HSR1 PF01926.23 OWF37250.1 - 0.013 15.6 0.2 2.2 8.4 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-LRR PF12061.8 OWF37250.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 ABC_tran PF00005.27 OWF37250.1 - 0.023 15.2 0.3 0.075 13.5 0.0 1.9 1 1 1 2 2 2 0 ABC transporter CbiA PF01656.23 OWF37250.1 - 0.023 14.7 0.0 0.062 13.4 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 OWF37250.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 NTPase CLP1_P PF16575.5 OWF37250.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF305 PF03713.13 OWF37250.1 - 0.037 14.2 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF305) AAA_18 PF13238.6 OWF37250.1 - 0.041 14.4 0.3 0.42 11.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 OWF37250.1 - 0.044 12.7 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Thymidylate_kin PF02223.17 OWF37250.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase SRP54 PF00448.22 OWF37250.1 - 0.051 13.2 0.0 0.57 9.8 0.0 2.3 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OWF37250.1 - 0.06 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CitG PF01874.16 OWF37250.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase AAA_29 PF13555.6 OWF37250.1 - 0.15 11.8 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lipase_GDSL_2 PF13472.6 OWF37251.1 - 1.9e-07 31.7 0.0 2.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lig_chan PF00060.26 OWF37252.1 - 1.6e-54 183.8 0.5 2.6e-54 183.1 0.5 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 OWF37252.1 - 7.2e-43 147.0 0.1 1.1e-42 146.5 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 OWF37252.1 - 5.4e-38 129.7 0.1 1.1e-37 128.7 0.1 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF37252.1 - 4.3e-24 85.2 0.0 7.2e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TPR_12 PF13424.6 OWF37253.1 - 9.7e-23 80.3 4.7 6.8e-08 32.7 0.0 4.5 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 OWF37253.1 - 8.5e-20 69.2 4.4 0.0011 18.9 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF37253.1 - 1.4e-18 65.5 8.0 8.4e-06 25.6 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 OWF37253.1 - 6.2e-17 60.6 10.6 5.1e-06 26.1 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF37253.1 - 2.1e-11 43.0 5.6 0.0079 16.2 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OWF37253.1 - 6.3e-11 41.8 2.2 2.9e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF37253.1 - 9.1e-09 35.4 0.1 4.3 8.4 0.1 5.9 5 1 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF37253.1 - 4.8e-06 27.1 0.9 1.8 9.3 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF37253.1 - 5.3e-06 26.0 1.1 8.7e-05 22.0 0.0 2.7 2 1 1 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 OWF37253.1 - 0.0001 22.7 0.4 7.9 7.4 0.0 6.0 6 1 0 6 6 6 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OWF37253.1 - 0.0014 18.6 6.4 0.019 15.0 0.2 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_11 PF13414.6 OWF37253.1 - 0.0018 17.9 7.1 1.9 8.3 0.0 5.1 5 1 1 6 6 6 2 TPR repeat RPN7 PF10602.9 OWF37253.1 - 0.0028 17.4 5.6 0.69 9.6 0.2 3.2 2 1 1 3 3 3 2 26S proteasome subunit RPN7 DUF3856 PF12968.7 OWF37253.1 - 0.0049 16.9 2.7 3 7.9 0.0 3.5 2 2 0 3 3 3 1 Domain of Unknown Function (DUF3856) SPO22 PF08631.10 OWF37253.1 - 0.0049 16.4 1.4 5.6 6.4 0.0 3.8 2 2 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_9 PF13371.6 OWF37253.1 - 0.019 15.1 0.0 75 3.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 OWF37253.1 - 0.057 13.7 0.0 10 6.6 0.0 3.6 3 0 0 3 3 3 0 PPR repeat DUF2225 PF09986.9 OWF37253.1 - 0.059 13.1 2.3 1.2 8.8 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 OWF37253.1 - 0.61 10.4 4.8 12 6.3 0.1 3.3 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OWF37253.1 - 5.2 7.7 5.0 36 5.1 0.1 4.4 5 1 1 6 6 5 0 Tetratricopeptide repeat Bromo_TP PF07524.13 OWF37254.1 - 3.9e-15 55.6 0.0 6.3e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 OWF37254.1 - 4.6e-05 23.6 0.0 9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Histone-fold protein NikR_C PF08753.11 OWF37254.1 - 0.048 13.8 1.0 0.048 13.8 1.0 2.0 2 0 0 2 2 2 0 NikR C terminal nickel binding domain AAA_6 PF12774.7 OWF37256.1 - 3.6e-127 423.8 0.0 1.4e-126 421.9 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF37256.1 - 3.1e-113 378.9 8.3 3.1e-113 378.9 8.3 4.6 4 2 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OWF37256.1 - 1.2e-71 240.4 2.4 1.2e-71 240.4 2.4 2.9 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 OWF37256.1 - 2.2e-53 181.2 0.0 1.6e-52 178.5 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 OWF37256.1 - 9.8e-39 132.1 0.1 7.6e-36 122.8 0.1 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain DHC_N1 PF08385.12 OWF37256.1 - 2.1e-38 132.3 0.2 2.1e-38 132.3 0.2 3.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 Dynein_C PF18199.1 OWF37256.1 - 6.4e-37 127.4 0.0 6.4e-37 127.4 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OWF37256.1 - 1.6e-35 122.4 0.0 4.1e-35 121.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF37256.1 - 2.6e-34 118.2 0.0 1.8e-22 79.8 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) MT PF12777.7 OWF37256.1 - 6e-30 104.4 13.9 1.5e-29 103.1 13.9 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 OWF37256.1 - 3.1e-28 98.5 1.4 5.6e-25 87.9 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_22 PF13401.6 OWF37256.1 - 1.2e-08 35.3 6.9 0.0017 18.7 0.0 5.8 5 1 1 6 6 5 2 AAA domain AAA PF00004.29 OWF37256.1 - 1.8e-07 31.6 0.2 1 9.8 0.0 5.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF37256.1 - 8.1e-06 26.3 20.4 0.025 15.0 0.0 7.4 8 1 1 9 9 5 2 AAA ATPase domain ABC_tran PF00005.27 OWF37256.1 - 1.8e-05 25.3 6.2 0.0032 18.0 0.0 5.3 5 0 0 5 5 3 1 ABC transporter RsgA_GTPase PF03193.16 OWF37256.1 - 1.8e-05 24.7 1.2 0.0038 17.2 0.0 4.0 4 0 0 4 4 3 1 RsgA GTPase AAA_30 PF13604.6 OWF37256.1 - 3.5e-05 23.6 0.6 0.027 14.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 OWF37256.1 - 0.00015 21.6 0.2 0.078 12.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 OWF37256.1 - 0.0025 17.8 4.2 0.15 12.0 0.0 3.5 4 0 0 4 4 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OWF37256.1 - 0.0028 18.0 0.1 0.36 11.3 0.1 3.6 3 0 0 3 3 3 1 RNA helicase AAA_29 PF13555.6 OWF37256.1 - 0.0064 16.2 0.1 0.22 11.3 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_28 PF13521.6 OWF37256.1 - 0.0072 16.6 0.1 0.12 12.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 OWF37256.1 - 0.0077 16.0 0.6 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OWF37256.1 - 0.017 15.6 0.9 0.49 11.0 0.0 4.0 3 0 0 3 3 2 0 AAA domain Dynein_AAA_lid PF17852.1 OWF37256.1 - 0.019 15.0 0.0 0.1 12.7 0.0 2.3 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain T2SSE PF00437.20 OWF37256.1 - 0.034 13.2 0.0 0.25 10.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 OWF37256.1 - 0.044 13.9 0.6 0.85 9.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 OWF37256.1 - 0.056 13.3 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_lid_7 PF17867.1 OWF37256.1 - 0.059 13.6 0.0 0.32 11.2 0.0 2.3 1 0 0 1 1 1 0 Midasin AAA lid domain AAA_lid_1 PF17857.1 OWF37256.1 - 0.062 13.5 0.5 0.24 11.6 0.1 2.3 2 0 0 2 2 1 0 AAA+ lid domain NACHT PF05729.12 OWF37256.1 - 0.068 13.1 2.8 17 5.3 0.1 4.1 4 0 0 4 4 3 0 NACHT domain TsaE PF02367.17 OWF37256.1 - 0.074 13.0 0.1 1.7 8.6 0.0 3.1 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_L11_N PF03946.14 OWF37256.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 1 0 Ribosomal protein L11, N-terminal domain AAA_14 PF13173.6 OWF37256.1 - 0.14 12.2 0.0 16 5.6 0.0 3.7 2 0 0 2 2 2 0 AAA domain DUF1192 PF06698.11 OWF37256.1 - 0.36 10.9 4.0 66 3.7 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Guanylate_kin PF00625.21 OWF37256.1 - 0.52 10.0 3.3 14 5.3 0.0 3.3 3 0 0 3 3 3 0 Guanylate kinase DUF3546 PF12066.8 OWF37256.1 - 1.1 9.5 3.9 0.95 9.7 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) WXG100 PF06013.12 OWF37256.1 - 1.2 9.4 4.8 38 4.6 0.2 4.8 2 1 0 2 2 2 0 Proteins of 100 residues with WXG AAA_19 PF13245.6 OWF37256.1 - 2.2 8.6 5.5 52 4.2 0.0 4.6 5 0 0 5 5 3 0 AAA domain MbeB_N PF04837.12 OWF37256.1 - 4 7.8 9.5 0.71 10.2 1.8 3.7 3 0 0 3 3 2 0 MbeB-like, N-term conserved region Sec34 PF04136.15 OWF37256.1 - 7 6.5 24.5 1.6 8.6 3.4 6.1 4 1 0 4 4 4 0 Sec34-like family KxDL PF10241.9 OWF37256.1 - 8 6.8 15.8 0.21 11.9 4.2 4.6 4 0 0 4 4 2 0 Uncharacterized conserved protein Cullin_binding PF03556.15 OWF37257.1 - 1.7e-31 109.2 1.9 2.5e-31 108.6 1.9 1.3 1 0 0 1 1 1 1 Cullin binding B3 PF02362.21 OWF37257.1 - 0.086 12.7 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 B3 DNA binding domain TraI_2 PF07514.11 OWF37257.1 - 0.094 11.6 0.0 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Putative helicase ADAM_CR_2 PF17771.1 OWF37258.1 - 3.4e-10 40.3 8.1 3.4e-10 40.3 8.1 2.2 3 0 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin PF01421.19 OWF37258.1 - 3.3e-08 33.7 0.2 8.1e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 OWF37258.1 - 6.2e-07 29.8 0.9 6.2e-07 29.8 0.9 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF37258.1 - 7.1e-06 26.6 0.1 2.4e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF37258.1 - 0.0025 17.7 2.6 0.0077 16.1 1.5 2.2 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF37258.1 - 0.0038 16.9 0.3 0.0076 15.9 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 OWF37258.1 - 0.0091 16.2 0.2 0.018 15.3 0.2 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Runt PF00853.19 OWF37258.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Runt domain SKG6 PF08693.10 OWF37259.1 - 0.0066 15.8 5.2 0.0066 15.8 5.2 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 OWF37259.1 - 0.012 15.4 1.5 0.018 14.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TadE PF07811.12 OWF37259.1 - 0.043 14.1 0.1 0.081 13.2 0.1 1.4 1 0 0 1 1 1 0 TadE-like protein XRN_N PF03159.18 OWF37259.1 - 1.1 8.6 7.2 1.9 7.8 4.9 2.1 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Sec_GG PF07549.14 OWF37260.1 - 0.012 15.1 0.6 2.1e+02 1.6 0.0 5.1 5 0 0 5 5 5 0 SecD/SecF GG Motif F-box_5 PF18511.1 OWF37260.1 - 1.6 8.4 4.6 2.3e+02 1.4 0.0 5.0 7 0 0 7 7 7 0 F-box ATP-synt_E PF05680.12 OWF37260.1 - 8.3 6.8 7.1 1.1e+02 3.3 0.1 3.8 2 1 3 5 5 5 0 ATP synthase E chain LapA_dom PF06305.11 OWF37261.1 - 0.00085 19.1 0.8 0.00085 19.1 0.8 2.8 3 0 0 3 3 1 1 Lipopolysaccharide assembly protein A domain DUF5385 PF17359.2 OWF37261.1 - 0.002 17.7 0.1 0.002 17.7 0.1 3.5 3 1 0 3 3 2 1 Family of unknown function (DUF5385) DUF5305 PF17231.2 OWF37261.1 - 0.0044 16.4 0.1 0.0044 16.4 0.1 2.3 3 0 0 3 3 3 1 Family of unknown function (DUF5305) Methuselah_N PF06652.12 OWF37261.1 - 0.0056 16.6 3.1 0.014 15.4 3.1 1.8 1 0 0 1 1 1 1 Methuselah N-terminus TMEM154 PF15102.6 OWF37261.1 - 0.0075 16.2 0.0 0.0075 16.2 0.0 3.3 4 0 0 4 4 2 1 TMEM154 protein family MGC-24 PF05283.11 OWF37261.1 - 0.0077 16.7 7.9 0.042 14.3 7.8 2.4 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin ECSCR PF15820.5 OWF37261.1 - 0.021 14.6 0.1 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator SIT PF15330.6 OWF37261.1 - 0.023 15.2 1.7 0.066 13.7 0.0 2.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Syndecan PF01034.20 OWF37261.1 - 0.028 14.3 0.2 0.092 12.7 0.2 1.8 1 0 0 1 1 1 0 Syndecan domain DUF4010 PF13194.6 OWF37261.1 - 0.034 13.8 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF4381 PF14316.6 OWF37261.1 - 0.036 14.3 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 OWF37261.1 - 0.046 14.6 4.2 0.21 12.5 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain HemY_N PF07219.13 OWF37261.1 - 0.051 13.8 0.2 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Saf_2TM PF18303.1 OWF37261.1 - 0.051 13.2 0.0 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain SKG6 PF08693.10 OWF37261.1 - 0.054 12.9 0.8 0.13 11.6 0.8 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DcuC PF03606.15 OWF37261.1 - 0.055 11.9 0.0 0.13 10.7 0.0 1.5 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Stevor PF17410.2 OWF37261.1 - 0.06 12.9 0.1 0.06 12.9 0.1 2.5 2 1 0 2 2 1 0 Subtelomeric Variable Open Reading frame MAP17 PF15807.5 OWF37261.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.3 2 1 1 3 3 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Adeno_E3_CR2 PF02439.15 OWF37261.1 - 0.13 12.0 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM100 PF16311.5 OWF37261.1 - 0.2 11.2 0.0 0.2 11.2 0.0 3.5 4 0 0 4 4 3 0 Transmembrane protein 100 LRR19-TM PF15176.6 OWF37261.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 1 0 Leucine-rich repeat family 19 TM domain Otopetrin PF03189.13 OWF37261.1 - 0.25 10.1 0.0 0.25 10.1 0.0 2.2 2 1 0 2 2 2 0 Otopetrin OAD_gamma PF04277.13 OWF37261.1 - 0.38 11.4 0.0 0.38 11.4 0.0 4.3 4 1 0 4 4 3 0 Oxaloacetate decarboxylase, gamma chain Orf78 PF06024.12 OWF37261.1 - 2.4 8.5 0.0 2.4 8.5 0.0 3.3 2 1 0 2 2 1 0 Orf78 (ac78) Hid1 PF12722.7 OWF37261.1 - 5.6 5.0 10.4 8.6 4.3 10.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.10 OWF37261.1 - 7.3 5.9 43.5 0.44 9.9 33.3 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Cadherin_C_2 PF16492.5 OWF37262.1 - 0.08 13.7 0.1 0.08 13.7 0.1 2.4 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF4271 PF14093.6 OWF37262.1 - 0.42 10.5 2.0 0.81 9.6 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Pam17 PF08566.10 OWF37263.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF16 PF01519.16 OWF37264.1 - 0.00052 20.5 1.8 0.042 14.3 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function DUF16 DUF4201 PF13870.6 OWF37264.1 - 0.019 14.7 0.2 7.6 6.2 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 OWF37264.1 - 0.033 14.4 1.5 0.095 12.9 0.0 2.2 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Tup_N PF08581.10 OWF37264.1 - 0.034 14.4 0.8 11 6.4 0.1 2.5 2 0 0 2 2 2 0 Tup N-terminal Spc42p PF11544.8 OWF37264.1 - 0.18 11.8 2.9 0.19 11.7 0.5 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p ATP_bind_2 PF03668.15 OWF37265.1 - 0.03 13.6 0.3 0.076 12.3 0.3 1.6 1 0 0 1 1 1 0 P-loop ATPase protein family Phage_Mu_Gam PF07352.12 OWF37265.1 - 0.062 13.2 0.1 0.062 13.2 0.1 3.3 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Tau95 PF09734.9 OWF37265.1 - 0.12 13.2 3.1 0.34 11.7 0.5 2.7 2 2 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF1664 PF07889.12 OWF37265.1 - 0.39 10.7 9.6 4.3 7.4 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ELMO_CED12 PF04727.13 OWF37266.1 - 1e-45 156.1 0.4 1.7e-45 155.3 0.2 1.4 2 0 0 2 2 2 1 ELMO/CED-12 family DUF1799 PF08809.11 OWF37266.1 - 0.013 15.6 0.0 0.093 12.9 0.0 2.1 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) TMEM131_like PF12371.8 OWF37267.1 - 2.9e-25 88.3 5.9 2.3e-24 85.5 0.1 4.5 6 0 0 6 6 6 1 Transmembrane protein 131-like ASH PF15780.5 OWF37267.1 - 5.9e-13 48.9 0.2 0.00052 20.2 0.0 6.8 6 0 0 6 6 6 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 OWF37267.1 - 1.5e-09 37.8 4.7 0.17 11.9 0.0 7.0 7 1 0 7 7 7 4 Protein of unknown function (DUF1573) DUF5001 PF16392.5 OWF37267.1 - 0.024 14.5 0.3 22 5.0 0.0 3.7 3 0 0 3 3 3 0 Ig-like domain zf-C2H2 PF00096.26 OWF37268.1 - 3e-16 58.9 21.1 4.5e-06 26.8 2.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF37268.1 - 4.5e-10 39.5 8.5 1.5e-07 31.5 1.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF37268.1 - 2.6e-07 30.9 18.8 0.0044 17.8 1.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 OWF37268.1 - 0.031 14.7 4.5 1.4 9.4 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF37268.1 - 0.066 13.5 4.7 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF37268.1 - 0.13 12.3 10.0 0.075 13.1 0.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 OWF37268.1 - 0.67 10.6 4.9 3.9 8.2 0.6 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-HC5HC2H_2 PF13832.6 OWF37269.1 - 8.1e-30 103.2 9.8 8.1e-30 103.2 9.8 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OWF37269.1 - 3e-24 85.1 8.3 3e-24 85.1 8.3 3.2 2 1 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OWF37269.1 - 2.2e-12 46.3 6.8 2.2e-12 46.3 6.8 3.1 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 OWF37269.1 - 3.6e-11 42.8 28.0 2.3e-10 40.2 9.8 3.2 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 OWF37269.1 - 2.1e-07 31.5 5.2 2.1e-07 31.5 5.2 3.1 2 1 0 2 2 2 1 Enhancer of polycomb-like LZ3wCH PF18517.1 OWF37269.1 - 0.0023 18.0 6.7 0.0084 16.2 2.5 3.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Peptidase_M9_N PF08453.10 OWF37269.1 - 0.037 13.7 0.1 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Peptidase family M9 N-terminal SH3_1 PF00018.28 OWF37271.1 - 2.4e-26 91.1 0.7 4.1e-14 51.9 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OWF37271.1 - 2.9e-25 87.9 0.2 5e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OWF37271.1 - 2.9e-20 71.7 0.0 2.6e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 OWF37271.1 - 2.8e-18 66.0 0.4 2.8e-18 66.0 0.4 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain hSH3 PF14603.6 OWF37271.1 - 0.0008 19.8 0.1 0.0076 16.7 0.0 2.6 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 OWF37271.1 - 0.0024 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain HUN PF08729.10 OWF37271.1 - 0.013 15.5 6.1 0.038 14.0 6.1 1.8 1 0 0 1 1 1 0 HPC2 and ubinuclein domain Vac14_Fab1_bd PF12755.7 OWF37271.1 - 0.018 15.7 0.5 0.044 14.4 0.1 1.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region MinE PF03776.14 OWF37271.1 - 0.073 13.1 0.2 8.2 6.5 0.0 3.0 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE Fasciclin PF02469.22 OWF37272.1 - 3.5e-102 337.6 0.2 2.3e-28 99.0 0.1 4.1 4 0 0 4 4 4 4 Fasciclin domain CAT PF00302.18 OWF37272.1 - 0.011 15.7 0.0 0.11 12.4 0.0 2.6 2 1 1 3 3 3 0 Chloramphenicol acetyltransferase Nro1 PF12753.7 OWF37272.1 - 0.039 12.9 0.1 5.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 DUF5645 PF18713.1 OWF37273.1 - 7e-05 23.1 0.0 40 4.5 0.0 6.1 1 1 9 10 10 10 2 Domain of unknown function (DUF5645) Yip1 PF04893.17 OWF37274.1 - 7.4e-10 38.8 14.8 1e-09 38.3 14.8 1.2 1 0 0 1 1 1 1 Yip1 domain Ribosomal_L6 PF00347.23 OWF37275.1 - 4.5e-24 84.9 0.5 4.7e-13 49.6 0.3 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Phytoreo_P8 PF07124.11 OWF37275.1 - 0.064 12.2 0.1 0.093 11.7 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Yip1 PF04893.17 OWF37276.1 - 3.9e-18 65.8 12.0 6.2e-18 65.1 11.7 1.4 1 1 0 1 1 1 1 Yip1 domain ERK-JNK_inhib PF15002.6 OWF37277.1 - 1.3e-61 207.7 0.2 1.6e-61 207.4 0.2 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Serglycin PF04360.12 OWF37277.1 - 0.029 14.3 1.0 0.49 10.3 0.2 2.1 2 0 0 2 2 2 0 Serglycin Otopetrin PF03189.13 OWF37278.1 - 2.4e-97 326.6 31.4 1.1e-69 235.3 13.0 3.0 2 1 1 3 3 3 3 Otopetrin Phage_holin_2_3 PF16080.5 OWF37278.1 - 0.45 10.3 0.0 0.45 10.3 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage holin family HP1 MIEAP PF16026.5 OWF37279.1 - 2.3e-29 103.0 0.2 2.3e-29 103.0 0.2 2.2 2 0 0 2 2 2 1 Mitochondria-eating protein DUF2046 PF09755.9 OWF37279.1 - 0.00013 21.3 4.5 0.00013 21.3 4.5 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Rho_Binding PF08912.11 OWF37279.1 - 0.014 16.2 7.3 2.9 8.8 0.9 3.9 3 1 1 4 4 4 0 Rho Binding GAS PF13851.6 OWF37279.1 - 0.014 14.7 9.9 0.27 10.6 0.6 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding FlxA PF14282.6 OWF37279.1 - 0.034 14.1 2.6 0.074 13.1 2.6 1.5 1 0 0 1 1 1 0 FlxA-like protein Sulfotransfer_4 PF17784.1 OWF37279.1 - 0.075 12.9 1.2 0.18 11.6 0.2 2.0 2 0 0 2 2 2 0 Sulfotransferase domain Prp19 PF08606.11 OWF37279.1 - 0.08 12.9 0.5 16 5.6 0.1 2.7 2 0 0 2 2 2 0 Prp19/Pso4-like DUF3584 PF12128.8 OWF37279.1 - 0.13 9.8 5.3 0.21 9.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 OWF37279.1 - 0.17 12.1 13.5 0.28 11.4 1.4 3.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 OWF37279.1 - 0.18 11.8 11.3 15 5.6 0.1 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 OWF37279.1 - 0.19 12.0 6.1 6.1 7.2 0.5 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2200 PF09966.9 OWF37279.1 - 0.22 11.7 1.2 0.47 10.6 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Herpes_BLRF2 PF05812.12 OWF37279.1 - 0.23 11.6 3.9 1.5 9.0 3.8 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein TolA_bind_tri PF16331.5 OWF37279.1 - 0.28 11.3 9.9 7.8 6.6 0.1 3.2 2 1 0 2 2 2 0 TolA binding protein trimerisation ZapB PF06005.12 OWF37279.1 - 0.28 11.6 7.6 1.7 9.2 0.4 3.1 3 0 0 3 3 3 0 Cell division protein ZapB FapA PF03961.13 OWF37279.1 - 0.3 9.6 4.4 0.13 10.9 1.9 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A UPF0242 PF06785.11 OWF37279.1 - 0.49 10.5 11.1 2.1 8.4 8.3 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Takusan PF04822.13 OWF37279.1 - 0.54 10.2 8.3 1.9 8.5 0.1 3.3 2 1 1 3 3 3 0 Takusan SlyX PF04102.12 OWF37279.1 - 0.61 10.7 7.7 5 7.8 1.0 2.7 1 1 1 2 2 2 0 SlyX SKA2 PF16740.5 OWF37279.1 - 0.61 9.9 6.5 3.7 7.4 3.2 3.2 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 DUF3958 PF13125.6 OWF37279.1 - 0.62 10.3 4.8 4.1 7.7 3.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) DUF4140 PF13600.6 OWF37279.1 - 0.68 10.4 4.4 1.5 9.3 0.2 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HalX PF08663.10 OWF37279.1 - 0.78 10.1 6.2 5.6 7.4 0.3 3.1 3 0 0 3 3 3 0 HalX domain Apolipoprotein PF01442.18 OWF37279.1 - 0.79 9.6 9.3 0.49 10.2 6.4 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Cep57_MT_bd PF06657.13 OWF37279.1 - 0.85 10.1 4.6 8.4 6.9 0.3 3.0 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 OWF37279.1 - 0.94 8.3 7.7 1 8.2 5.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Speriolin_N PF15058.6 OWF37279.1 - 1 9.4 3.6 15 5.6 0.1 2.5 3 0 0 3 3 2 0 Speriolin N terminus DUF4407 PF14362.6 OWF37279.1 - 1 8.6 6.3 1.9 7.7 6.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 OWF37279.1 - 1.5 9.0 7.0 0.31 11.2 1.6 2.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 OWF37279.1 - 1.6 9.2 17.8 9.7 6.7 0.6 4.0 2 1 2 4 4 4 0 Apg6 coiled-coil region BST2 PF16716.5 OWF37279.1 - 2.5 8.7 11.4 0.69 10.5 1.0 3.1 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Mto2_bdg PF12808.7 OWF37279.1 - 4 7.8 6.6 0.67 10.3 0.5 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMF_DNA_bd PF12329.8 OWF37279.1 - 4.5 7.4 6.8 7.3 6.7 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 OWF37279.1 - 5.2 7.4 12.7 4.2 7.7 1.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 OWF37279.1 - 7.6 6.7 12.2 2.7 8.1 6.2 2.6 2 1 1 3 3 2 0 Tropomyosin like Spc24 PF08286.11 OWF37279.1 - 7.8 6.8 9.3 4.4 7.6 1.5 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Saf_2TM PF18303.1 OWF37281.1 - 0.13 11.9 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Sulfate_transp PF00916.20 OWF37284.1 - 1.2e-103 346.9 24.7 1.5e-103 346.5 24.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OWF37284.1 - 5.4e-20 71.2 0.1 9.5e-20 70.4 0.1 1.4 1 0 0 1 1 1 1 STAS domain zf-RNPHF PF08080.12 OWF37284.1 - 0.029 14.3 0.1 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 RNPHF zinc finger Cdh1_DBD_1 PF18196.1 OWF37284.1 - 0.076 13.3 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 MAM PF00629.23 OWF37285.1 - 9.6e-13 48.4 0.0 4e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Chordopox_A33R PF05966.12 OWF37285.1 - 0.018 14.3 0.3 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Lectin_C PF00059.21 OWF37286.1 - 1e-08 35.8 1.7 1.3e-08 35.5 1.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain MAM PF00629.23 OWF37287.1 - 7.9e-32 110.4 1.6 2.7e-29 102.2 0.7 2.4 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Lectin_C PF00059.21 OWF37287.1 - 8.2e-17 61.9 0.8 2.6e-16 60.3 0.2 2.3 2 0 0 2 2 1 1 Lectin C-type domain TPR_MLP1_2 PF07926.12 OWF37287.1 - 0.00023 21.2 6.7 0.00041 20.4 6.7 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 OWF37287.1 - 0.00057 19.5 4.0 0.0011 18.5 4.0 1.4 1 0 0 1 1 1 1 fzo-like conserved region ERM PF00769.19 OWF37287.1 - 0.0023 17.8 0.2 0.0033 17.3 0.2 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family UPF0242 PF06785.11 OWF37287.1 - 0.0033 17.5 3.4 0.0051 16.9 3.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 OWF37287.1 - 0.0052 16.4 1.8 0.0081 15.8 1.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HAUS-augmin3 PF14932.6 OWF37287.1 - 0.0066 16.1 5.3 0.0098 15.5 5.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 OWF37287.1 - 0.012 14.5 6.0 0.018 14.0 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4763 PF15960.5 OWF37287.1 - 0.018 14.3 5.6 0.028 13.7 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) COG2 PF06148.11 OWF37287.1 - 0.031 14.4 1.4 0.061 13.4 1.4 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 OWF37287.1 - 0.039 14.0 5.8 0.07 13.1 5.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 OWF37287.1 - 0.071 13.5 0.8 0.11 12.9 0.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 OWF37287.1 - 0.093 13.3 4.7 0.047 14.2 1.8 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 OWF37287.1 - 0.15 12.2 0.6 0.31 11.3 0.6 1.5 1 0 0 1 1 1 0 Haemolysin XhlA NPV_P10 PF05531.12 OWF37287.1 - 0.55 10.7 9.0 0.41 11.1 5.4 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 OWF37287.1 - 0.55 10.0 5.6 0.91 9.3 5.6 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CCDC-167 PF15188.6 OWF37287.1 - 0.61 10.5 4.1 2.7 8.4 4.8 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TMPIT PF07851.13 OWF37287.1 - 1.2 8.3 4.9 1.6 7.9 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 OWF37287.1 - 1.6 9.2 6.0 0.41 11.1 0.6 2.5 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 OWF37287.1 - 1.8 8.8 6.9 15 5.9 3.5 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Lectin_C PF00059.21 OWF37288.1 - 1.1e-12 48.6 0.5 1.3e-12 48.4 0.5 1.0 1 0 0 1 1 1 1 Lectin C-type domain MAM PF00629.23 OWF37289.1 - 3.6e-28 98.5 0.1 4.2e-27 95.0 0.1 2.5 2 1 0 2 2 2 1 MAM domain, meprin/A5/mu DUF4407 PF14362.6 OWF37289.1 - 0.00073 19.0 4.8 0.0011 18.5 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CENP-H PF05837.12 OWF37289.1 - 0.035 14.5 4.1 0.058 13.8 4.1 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4763 PF15960.5 OWF37289.1 - 0.062 12.6 2.8 0.11 11.8 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF4140 PF13600.6 OWF37289.1 - 0.073 13.5 2.4 0.96 9.9 0.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 OWF37289.1 - 0.097 11.5 3.2 0.17 10.7 3.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cluap1 PF10234.9 OWF37289.1 - 0.12 11.8 2.0 0.18 11.2 2.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Filament PF00038.21 OWF37289.1 - 0.22 11.1 4.6 0.34 10.5 4.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein TolA_bind_tri PF16331.5 OWF37289.1 - 0.22 11.6 6.1 1.5 9.0 1.3 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Prominin PF05478.11 OWF37289.1 - 0.3 9.0 4.1 0.45 8.4 4.1 1.3 1 0 0 1 1 1 0 Prominin DUF812 PF05667.11 OWF37289.1 - 0.3 9.9 4.4 0.73 8.6 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Bacillus_HBL PF05791.11 OWF37289.1 - 0.53 10.1 9.8 1.2 9.0 9.8 1.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 OWF37289.1 - 0.57 10.3 7.5 0.94 9.6 7.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 OWF37289.1 - 0.58 10.2 4.2 5.6 7.0 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2703 PF10865.8 OWF37289.1 - 0.81 9.9 3.0 5 7.3 1.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2703) SlyX PF04102.12 OWF37289.1 - 1.3 9.7 8.8 3 8.5 3.2 2.3 1 1 1 2 2 2 0 SlyX DUF4097 PF13349.6 OWF37289.1 - 2.3 7.5 8.0 0.57 9.5 1.1 2.2 2 0 0 2 2 2 0 Putative adhesin KxDL PF10241.9 OWF37289.1 - 2.6 8.4 6.1 9.5 6.6 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein zf-CCHC_3 PF13917.6 OWF37290.1 - 1.1e-15 57.3 5.9 2.1e-15 56.4 5.9 1.5 1 0 0 1 1 1 1 Zinc knuckle BUD22 PF09073.10 OWF37290.1 - 0.19 11.0 42.4 0.21 10.9 42.4 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 OWF37290.1 - 0.27 9.7 42.5 0.28 9.7 42.5 1.0 1 0 0 1 1 1 0 Macoilin family UPF0524 PF15823.5 OWF37290.1 - 0.55 9.6 20.1 0.68 9.3 20.1 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 Peroxin-3 PF04882.12 OWF37290.1 - 0.6 9.0 32.0 0.83 8.6 32.0 1.1 1 0 0 1 1 1 0 Peroxin-3 CDC45 PF02724.14 OWF37290.1 - 0.93 7.7 29.5 1.3 7.2 29.5 1.2 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 OWF37290.1 - 0.97 8.5 29.1 1 8.4 29.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nucleo_P87 PF07267.11 OWF37290.1 - 2.2 7.0 20.8 2.7 6.7 20.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 OWF37290.1 - 2.2 6.4 29.7 2.5 6.2 29.7 1.0 1 0 0 1 1 1 0 Nop14-like family Menin PF05053.13 OWF37290.1 - 4.8 5.4 17.4 6.7 4.9 17.4 1.3 1 0 0 1 1 1 0 Menin Rrn6 PF10214.9 OWF37290.1 - 4.9 5.5 38.8 5.3 5.4 38.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 OWF37290.1 - 9.6 4.8 28.2 14 4.3 28.2 1.4 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 OWF37291.1 - 6.5e-19 68.3 0.0 2.3e-11 44.1 0.0 4.3 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF37291.1 - 2.9e-11 43.3 5.3 0.049 14.1 0.0 6.0 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OWF37291.1 - 3.6e-11 43.1 0.5 0.027 14.8 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37291.1 - 4.4e-11 42.0 3.9 0.19 12.4 0.0 6.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 OWF37291.1 - 7e-10 39.2 0.1 0.001 19.6 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF37291.1 - 0.001 19.4 1.9 0.0024 18.2 1.9 1.6 1 0 0 1 1 1 1 SOCS box RanGAP1_C PF07834.11 OWF37292.1 - 1.9e-54 184.0 0.0 2.9e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.6 OWF37292.1 - 5.8e-21 72.7 15.6 0.0047 16.9 0.0 9.4 9 0 0 9 9 9 7 Leucine Rich repeat LRR_1 PF00560.33 OWF37292.1 - 5.4e-05 23.2 2.0 63 4.7 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 OWF37292.1 - 0.0001 22.6 7.7 1.3 9.6 0.2 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF37292.1 - 0.00055 19.6 5.2 1.6 8.6 0.0 4.8 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 OWF37293.1 - 3.6e-26 88.9 23.1 6.5e-05 22.7 0.0 8.3 8 0 0 8 8 8 7 Leucine Rich repeat EF-hand_1 PF00036.32 OWF37293.1 - 1.7e-10 39.7 1.9 2.4e-05 23.6 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF37293.1 - 1.4e-09 38.2 2.8 7.1e-08 32.8 0.6 2.2 1 1 1 2 2 2 2 EF-hand domain pair LRR_1 PF00560.33 OWF37293.1 - 2.1e-08 33.6 13.9 14 6.7 0.0 8.8 9 1 0 9 9 9 1 Leucine Rich Repeat EF-hand_8 PF13833.6 OWF37293.1 - 5.2e-07 29.4 0.9 0.0013 18.5 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37293.1 - 5.4e-06 25.9 0.8 0.15 12.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain LRR_4 PF12799.7 OWF37293.1 - 9.7e-06 25.9 23.3 0.015 15.7 2.5 6.3 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) EF-hand_5 PF13202.6 OWF37293.1 - 0.0001 21.6 1.1 0.0052 16.2 0.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 OWF37293.1 - 0.049 13.6 0.5 0.16 12.0 0.4 1.8 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand LRR_8 PF13855.6 OWF37293.1 - 0.47 10.2 26.0 12 5.7 8.3 6.0 2 1 3 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 OWF37294.1 - 1.4e-23 80.9 4.6 0.018 15.1 0.0 8.2 8 0 0 8 8 8 6 Leucine Rich repeat EF-hand_7 PF13499.6 OWF37294.1 - 1.9e-10 41.0 0.9 1.9e-10 41.0 0.9 3.2 3 0 0 3 3 3 1 EF-hand domain pair LRR_1 PF00560.33 OWF37294.1 - 2.3e-08 33.5 0.1 8 7.4 0.0 6.8 6 0 0 6 6 6 1 Leucine Rich Repeat EF-hand_1 PF00036.32 OWF37294.1 - 3.5e-08 32.4 3.7 3.2e-05 23.2 1.2 4.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 OWF37294.1 - 6.9e-08 32.2 1.5 0.0082 16.0 0.1 3.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37294.1 - 1.6e-06 27.6 1.9 0.0023 17.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OWF37294.1 - 5.3e-06 25.7 5.9 0.00074 18.9 1.9 3.9 4 0 0 4 4 4 2 EF hand LRR_8 PF13855.6 OWF37294.1 - 0.00024 20.8 6.3 0.25 11.2 0.6 4.9 2 1 2 4 4 4 3 Leucine rich repeat EF-hand_4 PF12763.7 OWF37294.1 - 0.19 11.7 4.3 1.8 8.5 0.3 3.4 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand zf-U1 PF06220.12 OWF37296.1 - 1.6e-06 27.7 6.4 4.1e-06 26.4 6.4 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-CCCH PF00642.24 OWF37296.1 - 0.00057 19.7 4.5 0.0012 18.7 4.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.8 OWF37296.1 - 0.0043 17.3 5.5 0.023 15.0 5.5 2.3 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF37296.1 - 0.069 13.6 2.8 0.43 11.0 2.8 2.3 1 1 0 1 1 1 0 Zinc-finger of C2H2 type GA PF01468.17 OWF37296.1 - 0.11 12.8 0.4 0.11 12.8 0.4 1.8 2 0 0 2 2 2 0 GA module zf-C2H2_4 PF13894.6 OWF37296.1 - 0.25 12.3 0.2 0.25 12.3 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger TPR_16 PF13432.6 OWF37297.1 - 1.8 9.3 4.5 1.9 9.2 2.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat CARD PF00619.21 OWF37298.1 - 0.00041 20.3 0.1 0.0031 17.5 0.0 2.5 1 1 1 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 OWF37298.1 - 0.00073 19.5 0.1 0.011 15.7 0.0 2.8 2 0 0 2 2 2 1 Caspase recruitment domain Death PF00531.22 OWF37298.1 - 0.011 15.9 0.6 0.19 11.9 0.0 3.1 4 0 0 4 4 4 0 Death domain Spc7 PF08317.11 OWF37298.1 - 0.066 12.1 14.0 0.37 9.6 14.0 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1902 PF08972.11 OWF37298.1 - 0.087 12.8 0.2 2 8.5 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1902) Golgin_A5 PF09787.9 OWF37298.1 - 0.69 9.3 16.0 0.19 11.2 12.8 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4404 PF14357.6 OWF37298.1 - 2.7 8.7 12.7 0.3 11.8 1.5 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) Death PF00531.22 OWF37299.1 - 0.0021 18.2 0.5 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 Death domain KxDL PF10241.9 OWF37299.1 - 0.0075 16.5 11.5 0.39 11.0 0.7 3.3 3 0 0 3 3 3 2 Uncharacterized conserved protein Leu_zip PF15294.6 OWF37299.1 - 0.026 14.1 6.6 0.081 12.4 2.0 2.2 2 0 0 2 2 2 0 Leucine zipper Lebercilin PF15619.6 OWF37299.1 - 0.032 13.9 7.3 0.033 13.9 0.1 2.9 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease IL2 PF00715.17 OWF37299.1 - 0.05 13.5 0.4 0.05 13.5 0.4 2.3 2 1 1 3 3 3 0 Interleukin 2 SesA PF17107.5 OWF37299.1 - 0.061 13.5 7.1 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TMF_DNA_bd PF12329.8 OWF37299.1 - 0.097 12.7 0.6 0.097 12.7 0.6 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding GLE1 PF07817.13 OWF37299.1 - 0.11 11.7 3.2 0.077 12.2 0.5 1.9 2 0 0 2 2 2 0 GLE1-like protein DUF4303 PF14136.6 OWF37299.1 - 0.11 12.2 0.0 2.5 7.8 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4303) BAR_3 PF16746.5 OWF37299.1 - 0.14 11.9 3.6 1.8 8.2 2.0 2.3 2 0 0 2 2 2 0 BAR domain of APPL family LXG PF04740.12 OWF37299.1 - 0.19 11.5 5.7 2.9 7.6 1.2 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily Acetyltransf_11 PF13720.6 OWF37299.1 - 0.24 11.9 1.8 20 5.7 0.1 3.3 3 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF948 PF06103.11 OWF37299.1 - 0.29 11.4 7.3 3.9 7.8 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 OWF37299.1 - 0.41 10.7 10.6 0.35 11.0 0.8 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RRF_GI PF12614.8 OWF37299.1 - 0.75 10.0 4.4 0.27 11.4 0.5 2.2 2 1 1 3 3 2 0 Ribosome recycling factor DUF5082 PF16888.5 OWF37299.1 - 0.89 9.8 8.2 0.18 12.0 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) GPS2_interact PF15784.5 OWF37299.1 - 1.2 9.7 4.0 0.76 10.3 0.3 2.5 2 1 0 3 3 2 0 G-protein pathway suppressor 2-interacting domain Snapin_Pallidin PF14712.6 OWF37299.1 - 1.5 9.3 12.2 4.7 7.7 0.2 3.5 3 1 0 3 3 3 0 Snapin/Pallidin DUF2408 PF10303.9 OWF37299.1 - 1.9 9.0 7.5 20 5.7 5.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Prefoldin PF02996.17 OWF37299.1 - 7.1 6.6 8.2 4.9 7.1 0.6 2.9 3 0 0 3 3 3 0 Prefoldin subunit FA_hydroxylase PF04116.13 OWF37300.1 - 6.9e-22 78.2 14.0 1.9e-21 76.8 14.0 1.8 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Nup54 PF13874.6 OWF37301.1 - 1.1e-41 142.2 5.7 1.1e-41 142.2 5.7 2.5 3 0 0 3 3 3 2 Nucleoporin complex subunit 54 Nup54_C PF18437.1 OWF37301.1 - 4.1e-16 58.6 10.2 4.1e-16 58.6 10.2 3.0 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain Peptidase_M1 PF01433.20 OWF37302.1 - 5.9e-49 166.6 0.0 9.6e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OWF37302.1 - 6.2e-29 100.4 0.4 1.3e-28 99.4 0.4 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OWF37302.1 - 6.2e-19 68.9 0.0 1.1e-18 68.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 OWF37302.1 - 0.052 13.2 0.4 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Cadherin PF00028.17 OWF37303.1 - 3.7e-102 335.0 6.9 1.5e-20 73.4 0.1 7.3 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF37303.1 - 6.8e-19 67.5 0.6 4.3e-14 52.1 0.0 5.2 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 OWF37303.1 - 3.8e-06 26.9 8.0 0.11 12.5 0.1 4.9 5 0 0 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 OWF37303.1 - 0.0019 18.5 0.0 3.9 7.8 0.0 4.6 5 0 0 5 5 5 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 OWF37303.1 - 1.2 9.8 19.5 1.8 9.2 0.1 5.7 6 0 0 6 6 6 0 Bacterial cadherin-like domain Cadherin PF00028.17 OWF37304.1 - 6.8e-89 292.5 14.6 5.6e-18 65.2 0.0 7.4 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF37304.1 - 4.9e-14 51.9 1.6 1.6e-07 31.1 0.0 6.1 7 0 0 7 7 7 2 Cadherin-like RET_CLD1 PF17756.1 OWF37304.1 - 5.9e-05 23.3 0.1 25 5.2 0.0 5.0 4 1 0 4 4 4 1 RET Cadherin like domain 1 Cadherin_3 PF16184.5 OWF37304.1 - 0.004 17.1 13.2 0.0055 16.7 0.1 5.5 6 0 0 6 6 6 1 Cadherin-like TMEM154 PF15102.6 OWF37304.1 - 0.037 13.9 0.3 0.12 12.3 0.3 1.8 1 0 0 1 1 1 0 TMEM154 protein family Cadherin_4 PF17803.1 OWF37304.1 - 0.068 13.8 0.2 0.068 13.8 0.2 5.0 6 0 0 6 6 6 0 Bacterial cadherin-like domain Cadherin PF00028.17 OWF37305.1 - 2.2e-99 326.1 16.3 1.6e-17 63.7 0.1 7.5 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF37305.1 - 2.3e-08 33.8 0.2 8.2e-06 25.6 0.0 4.6 6 0 0 6 6 6 1 Cadherin-like DUF3377 PF11857.8 OWF37305.1 - 0.092 12.7 0.4 0.35 10.8 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 OWF37305.1 - 1.4 8.8 7.4 0.091 12.7 1.5 2.0 2 0 0 2 2 2 0 TMEM154 protein family APC_u13 PF16634.5 OWF37307.1 - 0.057 13.3 0.0 19 5.3 0.0 3.8 2 1 3 5 5 5 0 Unstructured region on APC between APC_crr and SAMP SF3b10 PF07189.11 OWF37307.1 - 0.16 12.1 0.0 30 4.8 0.0 2.8 1 1 2 4 4 4 0 Splicing factor 3B subunit 10 (SF3b10) Peptidase_M41 PF01434.18 OWF37307.1 - 0.17 11.7 0.0 1.6 8.6 0.0 1.8 1 1 1 2 2 2 0 Peptidase family M41 Fer4_11 PF13247.6 OWF37308.1 - 0.11 12.6 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Cadherin PF00028.17 OWF37310.1 - 4.1e-91 299.6 17.9 2.5e-17 63.1 0.1 7.3 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF37310.1 - 5.2e-13 48.6 3.1 1.2e-09 37.8 0.2 3.7 4 0 0 4 4 4 2 Cadherin-like Cadherin_4 PF17803.1 OWF37310.1 - 0.00091 19.8 28.0 0.0084 16.7 0.2 6.0 6 0 0 6 6 6 3 Bacterial cadherin-like domain RET_CLD1 PF17756.1 OWF37310.1 - 0.011 16.0 0.1 2.6 8.4 0.0 3.4 3 1 0 3 3 3 0 RET Cadherin like domain 1 Cadherin PF00028.17 OWF37311.1 - 1.1e-96 317.5 18.8 7e-18 64.9 0.1 7.9 8 0 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 OWF37311.1 - 1.3e-11 44.1 0.0 4.6e-07 29.6 0.0 4.0 3 0 0 3 3 3 2 Cadherin-like RET_CLD1 PF17756.1 OWF37311.1 - 1.6e-06 28.4 0.1 8.1 6.7 0.0 4.5 4 0 0 4 4 4 3 RET Cadherin like domain 1 TMEM154 PF15102.6 OWF37311.1 - 0.00048 20.1 0.3 0.0017 18.3 0.3 1.9 1 0 0 1 1 1 1 TMEM154 protein family Cadherin_3 PF16184.5 OWF37311.1 - 0.00091 19.2 10.2 0.27 11.3 0.1 5.5 7 0 0 7 7 7 2 Cadherin-like Herpes_gE PF02480.16 OWF37311.1 - 0.056 12.2 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Cadherin PF00028.17 OWF37313.1 - 1.2e-93 307.7 17.3 2.6e-16 59.8 0.0 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF37313.1 - 4e-11 42.6 4.1 4.6e-09 36.0 0.1 4.8 6 0 0 6 6 6 1 Cadherin-like Cadherin_3 PF16184.5 OWF37313.1 - 0.00029 20.8 15.2 1.1 9.3 0.1 6.4 6 0 0 6 6 6 2 Cadherin-like RET_CLD1 PF17756.1 OWF37313.1 - 0.0096 16.2 0.0 12 6.3 0.0 3.9 4 0 0 4 4 4 1 RET Cadherin like domain 1 Rax2 PF12768.7 OWF37313.1 - 0.052 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3313 PF11769.8 OWF37313.1 - 0.14 12.0 0.1 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3313) BACON PF13004.7 OWF37313.1 - 6 6.9 7.7 3.6 7.7 1.0 4.0 3 0 0 3 3 3 0 Putative binding domain, N-terminal Cadherin PF00028.17 OWF37314.1 - 2.5e-99 325.9 7.7 2.3e-22 79.2 0.4 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF37314.1 - 1.3e-11 44.2 0.1 4.9e-08 32.7 0.0 4.5 5 0 0 5 5 5 2 Cadherin-like Ig_3 PF13927.6 OWF37314.1 - 0.27 11.9 1.1 27 5.4 0.0 3.9 4 0 0 4 4 4 0 Immunoglobulin domain Cadherin_4 PF17803.1 OWF37314.1 - 5.2 7.8 32.4 0.68 10.6 0.8 5.9 6 0 0 6 6 6 0 Bacterial cadherin-like domain GP11 PF08677.10 OWF37315.1 - 0.054 13.0 0.0 0.077 12.4 0.0 1.3 1 1 0 1 1 1 0 GP11 baseplate wedge protein EGF PF00008.27 OWF37316.1 - 1.8e-05 25.0 9.9 6.1e-05 23.2 9.9 2.0 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 OWF37316.1 - 0.0079 16.8 6.6 0.0079 16.8 6.6 2.6 3 0 0 3 3 3 1 Human growth factor-like EGF Fibrinogen_C PF00147.18 OWF37316.1 - 0.021 14.6 0.1 0.05 13.4 0.0 1.5 1 1 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.13 OWF37316.1 - 0.44 11.0 13.7 0.24 11.8 10.6 2.1 2 0 0 2 2 2 0 EGF-like domain NIL PF09383.10 OWF37317.1 - 0.02 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 NIL domain Sulfotransfer_1 PF00685.27 OWF37318.1 - 1.5e-15 57.4 0.3 4.1e-15 56.0 0.3 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF37318.1 - 4.5e-15 56.6 0.0 1.2e-14 55.2 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family LRR_8 PF13855.6 OWF37319.1 - 1e-64 214.2 35.1 1.2e-12 47.4 3.3 8.7 3 2 5 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 OWF37319.1 - 4.2e-36 123.7 0.1 5.5e-12 45.8 0.0 4.8 2 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) 7tm_1 PF00001.21 OWF37319.1 - 4.4e-31 108.2 13.4 7.4e-31 107.4 13.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 OWF37319.1 - 4.3e-23 81.0 39.9 0.00064 20.1 0.0 10.5 6 3 5 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF37319.1 - 2e-13 50.2 21.3 4.1e-06 26.4 2.6 4.6 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OWF37319.1 - 7.4e-07 28.9 22.1 17 6.4 0.0 12.3 13 2 0 13 13 13 2 Leucine Rich Repeat LRRNT PF01462.18 OWF37319.1 - 0.14 11.8 1.7 0.28 10.9 0.3 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Bromodomain PF00439.25 OWF37320.1 - 2.4e-19 69.2 1.2 7.1e-19 67.7 0.4 2.3 2 0 0 2 2 2 1 Bromodomain zf-B_box PF00643.24 OWF37320.1 - 9.6e-12 44.9 23.5 1.3e-08 34.8 8.6 5.2 5 1 0 5 5 5 2 B-box zinc finger PHD PF00628.29 OWF37320.1 - 3e-08 33.4 10.2 3e-08 33.4 10.2 5.2 5 0 0 5 5 5 1 PHD-finger zf-C3HC4 PF00097.25 OWF37320.1 - 0.00016 21.5 2.2 0.00016 21.5 2.2 4.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF37320.1 - 0.00037 20.4 0.8 0.00037 20.4 0.8 4.7 5 1 1 6 6 6 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF37320.1 - 0.0056 16.5 2.7 0.0056 16.5 2.7 4.9 5 1 0 5 5 5 1 Prokaryotic RING finger family 4 XhlA PF10779.9 OWF37320.1 - 0.097 12.9 2.7 0.24 11.6 2.7 1.7 1 0 0 1 1 1 0 Haemolysin XhlA baeRF_family3 PF18845.1 OWF37320.1 - 0.14 12.4 0.6 0.34 11.1 0.6 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 OmpH PF03938.14 OWF37320.1 - 3.2 8.1 20.4 3.2 8.1 9.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RasGAP_C PF03836.15 OWF37320.1 - 3.4 7.8 14.7 0.064 13.4 6.2 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DEAD PF00270.29 OWF37321.1 - 1.1e-19 70.8 0.0 3.5e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF37321.1 - 4.2e-16 59.3 0.0 1.6e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OWF37321.1 - 3.3e-11 43.8 2.2 3.3e-11 43.8 2.2 2.8 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 OWF37321.1 - 1.2e-06 28.7 0.7 3.1e-06 27.3 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RQC PF09382.10 OWF37321.1 - 0.0032 17.2 0.0 2 8.2 0.0 2.8 2 0 0 2 2 2 2 RQC domain Alpha_Helical PF18489.1 OWF37321.1 - 0.013 15.7 0.2 0.04 14.1 0.2 1.8 1 0 0 1 1 1 0 Alpha helical domain CH PF00307.31 OWF37322.1 - 1.9e-82 272.6 3.3 1.4e-19 70.3 0.2 5.0 5 0 0 5 5 5 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 OWF37322.1 - 4.7e-11 43.0 0.8 1.7e-10 41.2 0.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF37322.1 - 1.8e-10 39.9 2.0 1.2e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF37322.1 - 1.3e-09 36.9 0.7 4.3e-05 22.7 0.0 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 OWF37322.1 - 1.3e-08 34.6 0.0 0.51 10.2 0.0 4.3 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_8 PF13833.6 OWF37322.1 - 5.6e-06 26.1 2.1 0.028 14.3 0.5 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF37322.1 - 3.8e-05 23.0 0.6 0.034 13.7 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 OWF37322.1 - 0.022 15.1 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain CH_2 PF06294.11 OWF37322.1 - 0.16 12.1 1.0 8.3 6.6 0.1 3.5 4 0 0 4 4 4 0 CH-like domain in sperm protein SAM_3 PF18016.1 OWF37323.1 - 1.7e-16 59.8 0.2 4.1e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PTB PF08416.13 OWF37323.1 - 5.4e-12 46.0 0.0 9.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.28 OWF37323.1 - 2.7e-07 30.1 0.1 7.5e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF37323.1 - 3.1e-07 30.0 0.2 8.3e-07 28.6 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 OWF37323.1 - 0.00039 20.6 0.8 0.00082 19.6 0.8 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_9 PF14604.6 OWF37323.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_4 PF06347.13 OWF37323.1 - 0.018 14.8 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Adaptin_binding PF10199.9 OWF37323.1 - 0.043 14.4 0.0 0.043 14.4 0.0 3.3 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Use1 PF09753.9 OWF37324.1 - 3.9e-06 26.8 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Pox_EPC_I2-L1 PF12575.8 OWF37324.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 Poxvirus entry protein complex L1 and I2 APG17 PF04108.12 OWF37324.1 - 0.004 16.3 0.2 0.005 16.0 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 RSN1_TM PF13967.6 OWF37324.1 - 0.0049 16.6 0.0 0.0054 16.5 0.0 1.3 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4407 PF14362.6 OWF37324.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.13 OWF37324.1 - 0.035 14.0 1.4 0.076 12.9 1.4 1.5 1 1 0 1 1 1 0 Sec20 Trypsin PF00089.26 OWF37325.1 - 2.2e-61 207.5 0.7 2.6e-61 207.3 0.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF37325.1 - 1.6e-08 35.6 0.0 2.4e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF37325.1 - 0.00016 22.0 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ammonium_transp PF00909.21 OWF37328.1 - 2.9e-108 362.1 27.5 3.3e-108 361.9 27.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.25 OWF37329.1 - 1.2e-50 172.4 0.0 2.3e-50 171.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37329.1 - 6.9e-24 84.5 0.0 1.1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SSP160 PF06933.11 OWF37329.1 - 0.012 13.9 3.7 0.021 13.0 3.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 APH PF01636.23 OWF37329.1 - 0.042 13.8 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OWF37329.1 - 0.099 12.0 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 7tm_1 PF00001.21 OWF37331.1 - 1.1e-19 70.8 19.0 1.1e-19 70.8 19.0 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 OWF37331.1 - 0.00027 20.6 12.6 0.00027 20.6 12.6 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc PSII_Ycf12 PF05969.11 OWF37331.1 - 0.12 12.4 3.8 0.31 11.1 3.8 1.8 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 DUF2530 PF10745.9 OWF37331.1 - 0.77 10.0 5.1 4.6 7.6 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Baculo_11_kDa PF06143.11 OWF37331.1 - 2.7 7.6 9.2 0.41 10.3 2.6 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family 7tm_1 PF00001.21 OWF37332.1 - 2.8e-20 72.8 21.2 3.8e-20 72.3 21.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sulfatase PF00884.23 OWF37333.1 - 1.6e-64 218.3 3.3 1.6e-64 218.3 3.3 1.6 2 0 0 2 2 2 1 Sulfatase Sulfatase_C PF14707.6 OWF37333.1 - 2.4e-07 31.5 0.1 5.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 OWF37333.1 - 4.3e-06 26.5 0.0 9.8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 OWF37333.1 - 0.029 14.6 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Pkinase PF00069.25 OWF37334.1 - 2e-19 70.0 0.0 4.3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37334.1 - 3.3e-14 52.8 0.0 7.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Band_7 PF01145.25 OWF37335.1 - 1.3e-26 93.7 0.0 1.7e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OWF37335.1 - 0.0011 18.7 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 OWF37335.1 - 0.029 14.8 0.3 0.076 13.4 0.3 1.7 1 0 0 1 1 1 0 Phage protein Gp68 ADAM_CR_2 PF17771.1 OWF37336.1 - 3.4e-14 53.1 4.2 3.4e-14 53.1 4.2 4.7 3 2 1 4 4 4 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF37336.1 - 4.7e-11 43.2 0.0 2.2e-10 41.0 0.0 2.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF37336.1 - 1.1e-09 38.9 1.2 9.8e-09 35.8 0.0 2.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF37336.1 - 3.5e-06 27.1 1.2 3.5e-06 27.1 1.2 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF37336.1 - 1e-05 25.3 0.1 2.4e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF37336.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Matrixin SecB PF02556.14 OWF37336.1 - 0.14 12.1 3.2 0.07 13.0 0.3 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit SecB Reprolysin PF01421.19 OWF37337.1 - 2e-12 47.4 0.0 4.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 OWF37337.1 - 1.2e-11 45.0 1.5 1.2e-11 45.0 1.5 4.2 4 2 0 4 4 4 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF37337.1 - 5.3e-07 30.0 0.0 1.3e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF37337.1 - 2.3e-06 28.1 0.0 5.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF37337.1 - 3.5e-05 23.8 0.5 6.9e-05 22.8 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF37337.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 OWF37337.1 - 0.085 12.5 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Agarase_CBM PF17992.1 OWF37337.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Agarase CBM like domain LAT PF15234.6 OWF37337.1 - 2.4 7.8 7.7 0.25 11.1 3.1 1.6 2 0 0 2 2 2 0 Linker for activation of T-cells VWA PF00092.28 OWF37338.1 - 7.7e-33 114.2 0.1 1.3e-32 113.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF37338.1 - 5.5e-14 52.7 0.3 5.5e-13 49.5 0.0 2.8 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF37338.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain CBM_14 PF01607.24 OWF37338.1 - 0.073 13.2 30.7 0.043 14.0 9.1 4.3 3 1 1 4 4 4 0 Chitin binding Peritrophin-A domain VWA PF00092.28 OWF37339.1 - 1.3e-26 93.9 0.4 2.4e-26 93.0 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF37339.1 - 5.9e-13 49.4 0.0 1.4e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF37339.1 - 1.9e-05 24.7 3.4 1.9e-05 24.7 3.4 4.0 3 1 0 3 3 3 1 Chitin binding Peritrophin-A domain Mucin PF01456.17 OWF37339.1 - 0.013 15.5 40.4 0.026 14.5 40.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein VWA_3 PF13768.6 OWF37339.1 - 0.092 12.7 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain MSA-2c PF12238.8 OWF37339.1 - 0.14 12.2 3.0 0.24 11.4 3.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c MGC-24 PF05283.11 OWF37339.1 - 0.72 10.3 13.0 1.7 9.1 13.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Dicty_REP PF05086.12 OWF37339.1 - 5 5.0 10.0 8 4.3 10.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 OWF37339.1 - 6.9 4.7 10.9 9.7 4.2 10.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus 7tm_3 PF00003.22 OWF37340.1 - 6.7e-60 202.8 28.5 1e-59 202.2 28.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OWF37340.1 - 4.6e-52 177.3 0.1 8.6e-52 176.4 0.1 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF37340.1 - 3e-09 37.0 0.0 6.3e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein Spore_III_AB PF09548.10 OWF37340.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Pil1 PF13805.6 OWF37341.1 - 1.3e-09 37.9 9.2 1.9e-09 37.4 9.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF1460 PF07313.12 OWF37341.1 - 0.02 14.3 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF3920 PF13058.6 OWF37341.1 - 0.061 13.5 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) zf-C4H2 PF10146.9 OWF37341.1 - 1.4 9.2 6.4 2.6 8.3 6.2 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1090 PF06476.12 OWF37341.1 - 5.9 7.0 11.2 0.1 12.7 3.6 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) AMP-binding PF00501.28 OWF37342.1 - 1.4e-94 317.1 0.0 1.6e-94 316.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF37342.1 - 2.1e-15 57.4 0.3 6.8e-15 55.8 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Complex1_LYR PF05347.15 OWF37343.1 - 1.1e-14 54.2 0.1 2.1e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OWF37343.1 - 1.3e-07 32.2 2.1 1.6e-07 32.0 2.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like SAS4 PF15460.6 OWF37343.1 - 0.02 15.0 0.2 0.023 14.8 0.2 1.3 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Complex1_LYR_1 PF13232.6 OWF37343.1 - 0.034 14.7 0.4 0.043 14.4 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like NAD_binding_1 PF00175.21 OWF37344.1 - 1.3e-35 122.3 0.0 2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OWF37344.1 - 3.3e-35 120.4 0.0 5e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OWF37344.1 - 1.5e-05 25.2 0.0 9e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OWF37344.1 - 0.18 12.1 0.0 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain SIR2 PF02146.17 OWF37345.1 - 5.3e-07 29.7 0.1 7.3e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Sir2 family SIR2 PF02146.17 OWF37346.1 - 2.9e-12 46.9 0.0 3.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family PNTB PF02233.16 OWF37346.1 - 0.0002 20.4 0.1 0.00027 20.0 0.1 1.1 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 OWF37346.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.5 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, central domain SH2 PF00017.24 OWF37348.1 - 1.2e-05 25.3 0.1 3.5e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 SH2 domain Neur_chan_LBD PF02931.23 OWF37349.1 - 1.6e-28 99.6 0.1 2.4e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF37349.1 - 2.9e-18 66.8 9.9 1.4e-17 64.5 1.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 OWF37349.1 - 0.35 10.3 9.5 1.2 8.5 2.5 2.7 3 0 0 3 3 3 0 Region of unknown function (DUF2417) p450 PF00067.22 OWF37350.1 - 7.1e-85 285.5 0.1 8.6e-85 285.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Raco_middle PF17651.1 OWF37350.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 RACo middle region MFS_1 PF07690.16 OWF37351.1 - 2.6e-32 112.1 25.9 5.3e-23 81.5 8.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF37351.1 - 1.4e-09 37.7 12.9 1.8e-06 27.5 5.4 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OWF37351.1 - 5.1 5.8 23.0 0.43 9.4 2.2 3.6 2 2 1 3 3 3 0 Sugar (and other) transporter Sulfotransfer_1 PF00685.27 OWF37352.1 - 6.1e-41 140.7 2.3 7.4e-40 137.1 2.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF37352.1 - 5.8e-08 33.4 0.1 3.8e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 Sulfotransferase family DUF2112 PF09885.9 OWF37352.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) VID27_PH PF17747.1 OWF37354.1 - 1.1 9.6 36.6 4.7 7.5 1.3 7.9 1 1 7 8 8 8 0 VID27 PH-like domain CDH PF02611.15 OWF37354.1 - 9.6 5.7 6.8 44 3.6 0.1 3.9 3 2 0 4 4 4 0 CDP-diacylglycerol pyrophosphatase Sulfotransfer_1 PF00685.27 OWF37355.1 - 1.2e-41 143.0 2.0 3.5e-41 141.5 2.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF37355.1 - 3.7e-06 27.5 0.0 1.4e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family Methyltransf_25 PF13649.6 OWF37356.1 - 5.2e-24 84.8 0.0 2.4e-20 73.0 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 OWF37356.1 - 5.6e-23 81.6 0.0 1.9e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF37356.1 - 4.8e-22 78.4 0.0 1.7e-18 67.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 OWF37356.1 - 4.5e-19 68.7 0.2 1.2e-18 67.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 OWF37356.1 - 4.6e-19 68.8 0.1 1.7e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OWF37356.1 - 2.3e-13 50.7 0.0 1.2e-12 48.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF37356.1 - 2.7e-13 49.8 0.1 1e-12 47.9 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OWF37356.1 - 4.4e-08 33.1 0.0 7.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OWF37356.1 - 1.4e-07 31.3 0.0 6.3e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.11 OWF37356.1 - 4e-06 26.0 0.0 8.4e-06 24.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) CheR PF01739.18 OWF37356.1 - 1.8e-05 24.3 0.2 0.0082 15.6 0.0 2.8 2 1 1 3 3 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 OWF37356.1 - 2.7e-05 23.5 0.0 0.00013 21.3 0.0 2.2 3 0 0 3 3 2 1 O-methyltransferase domain PrmA PF06325.13 OWF37356.1 - 8.1e-05 22.1 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 OWF37356.1 - 0.00017 21.1 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 OWF37356.1 - 0.00022 20.9 0.0 0.00048 19.7 0.0 1.6 2 0 0 2 2 1 1 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 OWF37356.1 - 0.00026 21.1 0.0 0.013 15.6 0.0 2.3 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OWF37356.1 - 0.00047 20.2 0.0 0.00099 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OWF37356.1 - 0.00081 19.0 0.0 0.0028 17.2 0.0 2.0 2 0 0 2 2 2 1 Histone methylation protein DOT1 MetW PF07021.12 OWF37356.1 - 0.0029 17.2 0.0 0.01 15.5 0.0 1.8 1 1 1 2 2 2 1 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 OWF37356.1 - 0.0033 17.4 0.0 0.062 13.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF938 PF06080.12 OWF37356.1 - 0.0045 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) TPMT PF05724.11 OWF37356.1 - 0.0057 16.3 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 OWF37356.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 OWF37356.1 - 0.016 14.7 0.2 0.24 10.8 0.0 2.5 2 0 0 2 2 2 0 Putative methyltransferase UPF0020 PF01170.18 OWF37356.1 - 0.031 13.9 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 OWF37356.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF1011 PF06237.12 OWF37357.1 - 1.7e-33 114.9 8.0 1.7e-33 114.9 8.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1011) Methyltransf_25 PF13649.6 OWF37358.1 - 1.9e-27 95.8 0.2 1.8e-13 51.0 0.0 3.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 OWF37358.1 - 1.6e-25 89.9 0.1 3.8e-16 59.4 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 OWF37358.1 - 1.1e-22 80.5 0.0 1.5e-12 48.0 0.0 3.0 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 OWF37358.1 - 7.9e-21 74.4 0.1 2e-09 37.4 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OWF37358.1 - 8.5e-18 64.9 0.2 2.2e-07 31.5 0.0 2.8 3 0 0 3 3 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 OWF37358.1 - 1.4e-13 50.7 1.2 3.2e-08 33.2 0.1 2.8 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 OWF37358.1 - 2.7e-11 43.4 0.0 6.7e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 OWF37358.1 - 4.8e-11 42.5 0.0 3.6e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase NodS PF05401.11 OWF37358.1 - 5e-11 42.6 0.0 5.2e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 OWF37358.1 - 6.8e-08 32.2 0.0 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase small domain TehB PF03848.14 OWF37358.1 - 9.7e-08 31.6 0.5 2.4e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 OWF37358.1 - 1.2e-07 31.0 0.1 1.4e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 OWF37358.1 - 7.5e-07 29.3 0.1 0.034 14.1 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain CheR PF01739.18 OWF37358.1 - 1.9e-06 27.5 0.2 0.036 13.5 0.0 2.7 2 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 OWF37358.1 - 2.2e-05 24.7 0.0 0.029 14.5 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase RrnaAD PF00398.20 OWF37358.1 - 0.00024 20.3 0.0 0.00064 18.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 OWF37358.1 - 0.00029 20.6 2.3 0.2 11.3 0.1 3.2 2 1 1 3 3 3 2 Lysine methyltransferase Met_10 PF02475.16 OWF37358.1 - 0.0006 19.6 0.0 0.06 13.1 0.0 2.5 2 0 0 2 2 2 1 Met-10+ like-protein PCMT PF01135.19 OWF37358.1 - 0.00084 19.1 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 OWF37358.1 - 0.005 16.2 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase domain PrmA PF06325.13 OWF37358.1 - 0.015 14.7 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MethyltransfD12 PF02086.15 OWF37358.1 - 0.02 14.6 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PMT2_N PF17987.1 OWF37358.1 - 0.031 14.4 1.9 0.073 13.3 0.4 2.5 2 1 0 2 2 2 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Methyltransf_4 PF02390.17 OWF37358.1 - 0.046 13.2 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 OWF37358.1 - 0.13 12.0 0.3 0.87 9.2 0.0 2.2 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF1295 PF06966.12 OWF37359.1 - 2.4e-72 243.3 0.9 2.9e-72 243.0 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OWF37359.1 - 6.3e-07 29.5 0.5 6.3e-07 29.5 0.5 2.1 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OWF37359.1 - 0.013 15.9 0.0 0.013 15.9 0.0 2.2 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OWF37359.1 - 0.018 15.4 0.1 0.018 15.4 0.1 2.5 4 0 0 4 4 4 0 Phospholipid methyltransferase Spore_YhaL PF14147.6 OWF37359.1 - 0.34 10.6 1.8 5.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Sporulation protein YhaL Carb_anhydrase PF00194.21 OWF37360.1 - 1.5e-47 162.3 0.0 1.8e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase C1q PF00386.21 OWF37361.1 - 4.7e-22 78.5 0.0 8.1e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF37361.1 - 0.003 17.5 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 BclA C-terminal domain TNF PF00229.18 OWF37361.1 - 0.021 14.7 0.1 0.26 11.2 0.1 2.3 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family LRR_8 PF13855.6 OWF37362.1 - 6.5e-16 57.9 25.0 5.7e-09 35.6 5.6 4.0 3 1 1 4 4 4 3 Leucine rich repeat TIR_2 PF13676.6 OWF37362.1 - 3.5e-09 37.3 0.2 7.7e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF37362.1 - 7.7e-09 35.6 0.8 1.5e-08 34.6 0.8 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF37362.1 - 5.6e-07 29.8 16.9 0.045 14.2 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF37362.1 - 0.00051 19.6 4.7 0.011 15.2 1.3 2.6 2 0 0 2 2 2 2 Leucine-rich repeat LRRNT PF01462.18 OWF37362.1 - 0.00076 19.1 2.9 0.00076 19.1 2.9 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 OWF37362.1 - 0.016 15.2 0.8 0.061 13.3 0.6 2.2 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) C1q PF00386.21 OWF37363.1 - 1.3e-24 86.8 0.1 2.3e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF37363.1 - 0.0013 18.7 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 BclA C-terminal domain TNF PF00229.18 OWF37363.1 - 0.026 14.4 0.1 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family LRR_8 PF13855.6 OWF37364.1 - 1.9e-13 50.0 18.8 8.4e-08 31.9 6.2 4.4 3 2 1 4 4 4 3 Leucine rich repeat TIR_2 PF13676.6 OWF37364.1 - 7.6e-08 33.0 0.1 1.9e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF37364.1 - 8.7e-07 29.2 17.2 0.054 13.9 0.3 5.5 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF37364.1 - 1.1e-06 28.6 0.4 2.4e-06 27.5 0.4 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF37364.1 - 7.2e-05 22.3 7.0 0.007 15.9 3.2 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRRNT PF01462.18 OWF37364.1 - 0.00079 19.0 2.7 0.00079 19.0 2.7 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 OWF37364.1 - 0.43 10.6 5.6 0.22 11.5 0.2 2.9 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) TIM21 PF08294.11 OWF37366.1 - 1e-42 145.4 0.1 1.3e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 OWF37366.1 - 3e-06 27.0 0.0 8.9e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Transglut_N PF00868.20 OWF37367.1 - 4.6e-26 91.5 0.0 1.5e-25 89.8 0.0 2.0 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 OWF37367.1 - 7.1e-15 55.4 0.1 2.5e-14 53.6 0.2 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Transglut_C PF00927.22 OWF37367.1 - 5.8e-09 36.0 0.1 0.00091 19.3 0.1 2.7 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Pup PF05639.11 OWF37367.1 - 0.95 10.4 3.0 0.54 11.2 0.1 2.1 2 0 0 2 2 2 0 Pup-like protein SRCR PF00530.18 OWF37368.1 - 1.1e-28 99.7 1.3 1.1e-28 99.7 1.3 2.4 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain Sushi PF00084.20 OWF37368.1 - 2.3e-10 40.9 1.9 2.3e-10 40.9 1.9 1.9 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) SRCR_2 PF15494.6 OWF37368.1 - 7e-05 23.3 0.1 7e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain PAN_1 PF00024.26 OWF37368.1 - 0.012 15.5 1.1 0.02 14.8 0.1 2.0 2 0 0 2 2 2 0 PAN domain 7TM_GPCR_Srw PF10324.9 OWF37369.1 - 6.8e-27 94.6 22.1 9.9e-27 94.1 22.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF37369.1 - 5.1e-20 71.9 17.2 6.7e-20 71.5 17.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF37369.1 - 0.00012 21.8 22.0 0.00012 21.8 22.0 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5305 PF17231.2 OWF37369.1 - 0.063 12.7 0.6 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4044 PF13253.6 OWF37369.1 - 8.5 6.0 9.8 0.31 10.6 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Amidohydro_2 PF04909.14 OWF37370.1 - 6.3e-40 137.8 0.2 8e-40 137.4 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.21 OWF37370.1 - 0.0052 16.0 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) LEDGF PF11467.8 OWF37370.1 - 0.0084 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Galactosyl_T PF01762.21 OWF37371.1 - 1.7e-41 142.2 0.6 2.5e-41 141.6 0.6 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF37371.1 - 0.023 14.2 0.0 0.041 13.3 0.0 1.5 1 1 0 1 1 1 0 Fringe-like HTH_25 PF13413.6 OWF37371.1 - 0.078 12.8 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Exo_endo_phos PF03372.23 OWF37372.1 - 6e-10 39.0 0.0 1.4e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GP11 PF08677.10 OWF37372.1 - 0.12 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 GP11 baseplate wedge protein Exo_endo_phos PF03372.23 OWF37375.1 - 0.00012 21.7 0.0 0.00069 19.2 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPATA48 PF15073.6 OWF37376.1 - 0.00035 20.9 0.2 0.00087 19.6 0.2 1.7 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 L_HMGIC_fpl PF10242.9 OWF37377.1 - 9.1e-05 22.7 4.4 9.1e-05 22.7 4.4 1.5 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 OWF37377.1 - 0.021 14.7 5.0 0.035 14.0 5.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 OWF37377.1 - 0.11 12.4 8.5 0.043 13.7 3.6 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein CoA_binding_3 PF13727.6 OWF37377.1 - 0.38 10.7 2.0 0.49 10.4 1.1 1.6 1 1 0 1 1 1 0 CoA-binding domain Claudin_3 PF06653.11 OWF37377.1 - 0.41 10.6 14.3 4.7 7.1 14.3 2.2 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Claudin_2 PF13903.6 OWF37377.1 - 2.7 7.7 11.8 54 3.5 9.6 2.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TctB PF07331.11 OWF37377.1 - 9.1 6.6 14.1 1.9 8.7 0.7 2.8 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family PEPCK_GTP PF00821.18 OWF37378.1 - 3.8e-160 532.6 0.4 4.6e-160 532.3 0.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 OWF37378.1 - 2.3e-93 311.8 0.0 3.1e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain DUF3512 PF12024.8 OWF37379.1 - 7.8e-82 274.3 2.0 7.8e-82 274.3 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 OWF37379.1 - 1.3e-17 63.6 1.3 2.4e-17 62.8 1.3 1.5 1 0 0 1 1 1 1 Bromodomain Prok-E2_C PF14459.6 OWF37379.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C DNA_pol_A_exo1 PF01612.20 OWF37380.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease P4Ha_N PF08336.11 OWF37380.1 - 0.095 12.7 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DNA_pol_A_exo1 PF01612.20 OWF37381.1 - 2.2e-05 24.2 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF4710 PF15828.5 OWF37381.1 - 0.012 15.7 0.6 0.024 14.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Glyco_transf_11 PF01531.16 OWF37382.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 11 CAS_C PF12026.8 OWF37383.1 - 3.2e-63 213.6 3.2 3.2e-63 213.6 3.2 1.8 2 0 0 2 2 2 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 OWF37383.1 - 3.8e-45 153.7 3.3 1.1e-44 152.2 3.3 1.9 1 0 0 1 1 1 1 Serine rich protein interaction domain SH3_1 PF00018.28 OWF37383.1 - 3.6e-09 36.1 0.0 7.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF37383.1 - 2.4e-08 33.7 0.1 4.6e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF37383.1 - 7.4e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DNA_gyraseA_C PF03989.13 OWF37384.1 - 0.0018 17.7 22.8 7.2 6.2 0.1 7.4 2 2 9 11 11 11 7 DNA gyrase C-terminal domain, beta-propeller UCH_N PF16674.5 OWF37384.1 - 1.7 8.6 19.8 6.5 6.7 0.7 4.7 1 1 3 4 4 4 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 LRR_6 PF13516.6 OWF37384.1 - 5.6 7.3 5.5 1e+02 3.3 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich repeat CPSF_A PF03178.15 OWF37386.1 - 6.4e-84 282.0 0.3 9.6e-82 274.9 0.0 3.6 4 0 0 4 4 4 1 CPSF A subunit region MMS1_N PF10433.9 OWF37386.1 - 3.3e-43 148.1 0.0 2.5e-42 145.2 0.0 2.2 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Tyrosinase PF00264.20 OWF37387.1 - 1.7e-26 93.9 11.1 1.2e-25 91.1 0.1 3.7 4 1 0 4 4 4 1 Common central domain of tyrosinase CBM_14 PF01607.24 OWF37387.1 - 0.024 14.8 13.3 0.021 15.0 9.3 2.8 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Sporozoite_P67 PF05642.11 OWF37387.1 - 0.17 9.9 6.3 0.26 9.3 6.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 OWF37387.1 - 2.1 8.3 40.3 4.5 7.3 40.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein BTK PF00779.19 OWF37388.1 - 0.007 16.2 0.4 0.016 15.0 0.4 1.6 1 0 0 1 1 1 1 BTK motif HH_signal PF01085.18 OWF37388.1 - 0.041 13.5 0.3 0.074 12.7 0.3 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain DUF5449 PF17528.2 OWF37388.1 - 0.058 13.2 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5449) Sas10_Utp3 PF04000.15 OWF37389.1 - 3.9e-15 56.2 0.7 3.9e-15 56.2 0.7 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family THOC7 PF05615.13 OWF37389.1 - 0.21 11.9 9.3 0.59 10.4 9.3 1.8 1 0 0 1 1 1 0 Tho complex subunit 7 Peptidase_C14 PF00656.22 OWF37390.1 - 1.8e-20 73.9 0.0 2.8e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Caspase domain LCIB_C_CA PF18599.1 OWF37390.1 - 0.056 12.7 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF1011 PF06237.12 OWF37391.1 - 5.4e-37 126.1 10.6 5.4e-37 126.1 10.6 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1011) Methyltransf_11 PF08241.12 OWF37392.1 - 1.8e-11 44.5 0.0 2.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF37392.1 - 5.8e-11 43.0 0.0 9.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 OWF37392.1 - 3.2e-10 39.9 0.0 4.3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 OWF37392.1 - 1.4e-06 28.0 0.0 7.7e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.20 OWF37392.1 - 0.00017 20.7 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 OWF37392.1 - 0.00037 20.0 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.6 OWF37392.1 - 0.00046 20.0 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF37392.1 - 0.00088 19.1 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OWF37392.1 - 0.0014 18.1 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 OWF37392.1 - 0.0022 18.7 0.0 0.0035 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF37392.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ldl_recept_a PF00057.18 OWF37393.1 - 3.3e-11 43.2 33.3 2.5e-06 27.6 8.6 3.6 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Frizzled PF01534.17 OWF37393.1 - 0.053 12.6 0.0 0.65 9.0 0.0 2.1 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region zf-C4 PF00105.18 OWF37394.1 - 5.7e-31 106.8 12.1 1.1e-30 105.9 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF37394.1 - 1.1e-26 93.8 6.6 3.3e-26 92.2 6.6 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PhyH PF05721.13 OWF37395.1 - 5.1e-33 115.1 0.0 6.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OWF37395.1 - 0.016 14.0 0.0 1 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) DBR1 PF05011.13 OWF37395.1 - 0.16 12.4 0.0 0.47 10.9 0.0 1.9 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain PhyH PF05721.13 OWF37396.1 - 7e-30 104.9 0.0 1e-29 104.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OWF37396.1 - 0.0079 16.6 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.12 OWF37396.1 - 0.059 12.1 0.0 0.52 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Coatomer_g_Cpla PF16381.5 OWF37397.1 - 0.11 12.6 0.2 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform PhyH PF05721.13 OWF37398.1 - 1.5e-58 198.5 0.0 1.8e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cag12 PF13117.6 OWF37398.1 - 0.1 13.1 0.4 1.4 9.5 0.1 2.2 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 DHHC PF01529.20 OWF37399.1 - 6.3e-37 126.7 5.8 6.3e-37 126.7 5.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase EcsB PF05975.12 OWF37399.1 - 0.11 11.3 4.5 0.029 13.2 1.2 1.6 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB DUF4022 PF13214.6 OWF37399.1 - 0.21 11.9 3.6 0.71 10.2 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) Yip1 PF04893.17 OWF37399.1 - 0.37 10.5 6.4 0.037 13.8 1.2 1.8 2 0 0 2 2 2 0 Yip1 domain Acyl-CoA_dh_1 PF00441.24 OWF37400.1 - 1.3e-46 158.6 0.9 2e-46 157.9 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OWF37400.1 - 5.9e-30 104.2 0.1 1.2e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OWF37400.1 - 1.6e-27 95.5 0.3 3.2e-27 94.6 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF37400.1 - 2.1e-17 63.7 1.2 3.1e-17 63.1 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OWF37400.1 - 3.5e-05 23.6 0.2 0.00014 21.6 0.2 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MACPF PF01823.19 OWF37401.1 - 6.1e-22 78.8 0.7 1.1e-21 78.0 0.7 1.4 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 OWF37402.1 - 7.4e-21 75.2 0.4 1.4e-20 74.3 0.4 1.5 1 0 0 1 1 1 1 MAC/Perforin domain SUR7 PF06687.12 OWF37402.1 - 0.054 13.1 0.1 2.6 7.6 0.3 2.4 2 0 0 2 2 2 0 SUR7/PalI family cEGF PF12662.7 OWF37402.1 - 2 8.4 6.0 59 3.7 2.8 3.9 2 1 0 2 2 2 0 Complement Clr-like EGF-like TMEM154 PF15102.6 OWF37402.1 - 2 8.3 7.6 0.25 11.2 0.4 2.4 2 0 0 2 2 2 0 TMEM154 protein family Syntaxin-6_N PF09177.11 OWF37403.1 - 4e-39 133.2 9.1 3.1e-38 130.3 2.2 2.4 2 1 0 2 2 2 2 Syntaxin 6, N-terminal SNARE PF05739.19 OWF37403.1 - 1.1e-10 41.3 1.3 1.1e-10 41.3 1.3 3.2 4 0 0 4 4 4 1 SNARE domain KH_5 PF13184.6 OWF37403.1 - 0.006 16.6 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 NusA-like KH domain DUF1359 PF07097.11 OWF37403.1 - 0.022 15.0 0.5 0.057 13.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) Muted PF14942.6 OWF37403.1 - 0.43 10.9 10.2 0.42 10.9 4.2 2.6 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein UPF0184 PF03670.13 OWF37403.1 - 0.52 10.7 3.9 0.35 11.3 0.6 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF2203 PF09969.9 OWF37403.1 - 0.76 10.5 3.5 25 5.6 0.6 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec34 PF04136.15 OWF37403.1 - 2.5 8.0 6.7 0.75 9.7 0.3 2.5 2 1 1 3 3 3 0 Sec34-like family DUF16 PF01519.16 OWF37403.1 - 6.7 7.3 9.0 2.4 8.7 3.8 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 Occludin_ELL PF07303.13 OWF37403.1 - 6.8 7.5 9.1 24 5.7 3.6 3.3 2 2 1 3 3 3 0 Occludin homology domain UNC80 PF15778.5 OWF37404.1 - 4.7e-78 261.1 0.1 1e-77 260.0 0.1 1.6 1 0 0 1 1 1 1 Cation channel complex component UNC80 ADK PF00406.22 OWF37406.1 - 5.4e-48 162.9 0.0 9.7e-31 106.9 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 OWF37406.1 - 2e-25 89.8 0.0 8.6e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Hydin_ADK PF17213.3 OWF37406.1 - 5.8e-11 43.0 2.0 0.036 14.3 0.0 4.1 4 0 0 4 4 4 3 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 OWF37406.1 - 3.1e-08 34.2 0.0 0.00036 21.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OWF37406.1 - 1e-06 28.9 0.0 0.00042 20.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OWF37406.1 - 0.00012 21.8 0.2 0.0042 16.9 0.1 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF5582 PF17819.1 OWF37406.1 - 0.00096 19.6 0.3 0.0022 18.4 0.1 1.7 2 0 0 2 2 1 1 Family of unknown function (DUF5582) AAA PF00004.29 OWF37406.1 - 0.0025 18.2 0.6 2.7 8.4 0.1 2.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF37406.1 - 0.0067 16.8 0.0 4.7 7.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.27 OWF37406.1 - 0.0068 16.9 0.0 1.4 9.4 0.0 2.4 2 1 0 2 2 2 1 ABC transporter DUF5586 PF17824.1 OWF37406.1 - 0.0089 15.2 0.1 0.018 14.2 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5586) Cytidylate_kin PF02224.18 OWF37406.1 - 0.011 15.4 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase SRPRB PF09439.10 OWF37406.1 - 0.068 12.6 0.2 3.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SKI PF01202.22 OWF37406.1 - 0.072 13.2 2.9 0.81 9.8 0.1 3.4 3 2 0 3 3 3 0 Shikimate kinase AAA_28 PF13521.6 OWF37406.1 - 0.1 12.8 0.0 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF37406.1 - 0.11 12.0 0.1 3 7.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OWF37406.1 - 0.12 12.0 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Innexin PF00876.18 OWF37407.1 - 3e-58 197.8 4.3 3.5e-58 197.6 4.3 1.0 1 0 0 1 1 1 1 Innexin Tudor_FRX1 PF18336.1 OWF37407.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain Innexin PF00876.18 OWF37408.1 - 1.9e-58 198.4 7.6 2.2e-58 198.3 7.6 1.0 1 0 0 1 1 1 1 Innexin ADH_zinc_N PF00107.26 OWF37409.1 - 8.6e-23 80.7 1.5 1.5e-22 79.9 1.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF37409.1 - 2.6e-14 54.4 0.0 4.5e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF37409.1 - 9e-12 44.8 0.0 2.7e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PHP_C PF13263.6 OWF37409.1 - 0.0018 18.0 0.4 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 PHP-associated Aminotran_5 PF00266.19 OWF37410.1 - 4.3e-24 85.1 0.0 7.2e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OWF37410.1 - 0.0016 17.0 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OWF37410.1 - 0.0036 16.5 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 OWF37410.1 - 0.0038 16.0 0.0 0.0059 15.4 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 OWF37410.1 - 0.029 13.7 0.1 0.057 12.7 0.1 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SH3_2 PF07653.17 OWF37410.1 - 0.06 13.0 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain Tubulin PF00091.25 OWF37411.1 - 2.2e-68 230.3 0.0 3e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF37411.1 - 1.9e-52 176.7 0.0 2.9e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OWF37411.1 - 0.00036 20.3 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RabGAP-TBC PF00566.18 OWF37412.1 - 1.7e-52 178.2 1.4 1.7e-52 178.2 1.4 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 OWF37412.1 - 8.7e-32 110.9 0.0 5.2e-31 108.4 0.0 2.4 1 1 0 1 1 1 1 Kinesin protein PID PF00640.23 OWF37412.1 - 2.2e-06 27.7 0.1 2.2e-06 27.7 0.1 3.0 3 0 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 OWF37412.1 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 1 0 0 1 1 1 0 Phosphotyrosine-binding domain PID_2 PF14719.6 OWF37412.1 - 0.02 14.8 0.0 0.076 12.9 0.0 2.0 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) ERM PF00769.19 OWF37412.1 - 0.053 13.3 29.7 0.1 12.4 29.7 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family YabA PF06156.13 OWF37412.1 - 1.9 9.1 22.5 1.3 9.7 5.6 3.9 2 1 1 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 OWF37412.1 - 3.6 6.4 32.5 5.2 5.9 5.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein SIKE PF05769.11 OWF37412.1 - 8.2 6.3 28.0 0.53 10.2 20.3 2.3 1 1 1 2 2 2 0 SIKE family Ldl_recept_b PF00058.17 OWF37416.1 - 2.2e-20 72.8 13.1 5.7e-05 23.5 0.2 6.3 6 0 0 6 6 6 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 OWF37416.1 - 6.3e-18 64.8 47.9 8.3e-08 32.4 8.1 4.4 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site Sushi PF00084.20 OWF37416.1 - 1.9e-05 25.1 20.7 0.0038 17.8 4.6 4.0 3 1 1 4 4 4 2 Sushi repeat (SCR repeat) SGL PF08450.12 OWF37416.1 - 0.00095 18.8 7.1 5.6 6.5 0.0 5.9 4 2 0 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 OWF37416.1 - 0.0021 17.9 0.8 0.0021 17.9 0.8 5.6 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF PF00008.27 OWF37416.1 - 0.014 15.6 6.4 0.014 15.6 6.4 3.9 3 0 0 3 3 3 0 EGF-like domain PQQ_2 PF13360.6 OWF37416.1 - 0.16 11.6 0.2 11 5.5 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Ldl_recept_b PF00058.17 OWF37417.1 - 2.3e-21 76.0 11.4 9.9e-05 22.7 0.1 6.6 6 0 0 6 6 6 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 OWF37417.1 - 1.4e-12 47.6 29.7 1.3e-07 31.7 8.1 2.9 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF37417.1 - 4.7e-05 23.2 9.5 0.00024 21.0 1.4 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like SGL PF08450.12 OWF37417.1 - 7.6e-05 22.4 8.3 4.4 6.8 0.3 6.5 3 3 2 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region EGF PF00008.27 OWF37417.1 - 0.0014 18.9 4.4 0.0014 18.9 4.4 2.6 2 0 0 2 2 2 1 EGF-like domain 4HBT_2 PF13279.6 OWF37418.1 - 4.8e-05 23.8 0.0 0.036 14.6 0.0 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF37418.1 - 0.00019 20.8 0.0 0.00032 20.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-ACP thioesterase O-FucT PF10250.9 OWF37422.1 - 1e-75 255.6 0.2 1.2e-75 255.3 0.2 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Neur_chan_LBD PF02931.23 OWF37423.1 - 1.4e-62 211.0 1.2 1.4e-62 211.0 1.2 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF37423.1 - 4.2e-43 148.1 0.4 6.1e-43 147.6 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TraL PF07178.11 OWF37423.1 - 0.016 15.6 0.1 0.063 13.8 0.1 2.0 1 0 0 1 1 1 0 TraL protein DUF2417 PF10329.9 OWF37423.1 - 1.4 8.3 9.6 0.11 11.9 4.4 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) tRNA_m1G_MT PF01746.21 OWF37424.1 - 2.4e-09 37.2 21.6 1.2 8.8 2.0 7.6 1 1 2 3 3 3 2 tRNA (Guanine-1)-methyltransferase DUF2345 PF10106.9 OWF37424.1 - 4.2e-09 36.5 37.8 0.0041 17.0 13.4 3.4 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2345) Fibrinogen_BP PF08017.11 OWF37424.1 - 4.4e-07 28.7 0.0 5.8e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein GSH-S_N PF02951.14 OWF37424.1 - 0.031 14.4 20.0 84 3.3 6.0 4.7 1 1 1 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain Rsc14 PF08586.10 OWF37424.1 - 4.5 8.1 24.4 49 4.8 0.3 6.2 1 1 2 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit Pyridoxal_deC PF00282.19 OWF37425.1 - 2.4e-13 49.6 0.0 1.3e-07 30.7 0.0 2.6 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Flavi_glycoprot PF00869.20 OWF37426.1 - 0.051 12.8 0.1 0.094 11.9 0.1 1.3 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains EGF_CA PF07645.15 OWF37427.1 - 8.4e-31 105.9 123.2 2.7e-10 40.3 12.5 17.9 15 2 1 16 16 16 9 Calcium-binding EGF domain VWD PF00094.25 OWF37427.1 - 1.2e-24 87.4 0.1 3.9e-24 85.7 0.1 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_3 PF12947.7 OWF37427.1 - 6.1e-23 80.7 108.4 1.8e-08 34.4 13.1 19.5 20 2 0 20 20 20 9 EGF domain cEGF PF12662.7 OWF37427.1 - 5.1e-19 67.9 125.2 1.4e-05 24.9 0.5 14.3 13 0 0 13 13 13 8 Complement Clr-like EGF-like RAP PF08373.10 OWF37428.1 - 0.00012 22.1 0.1 0.00034 20.6 0.1 1.8 1 0 0 1 1 1 1 RAP domain FAST_2 PF08368.12 OWF37428.1 - 0.0031 18.3 1.1 0.06 14.1 0.0 3.5 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 OWF37428.1 - 0.84 9.6 4.4 24 4.9 0.8 4.2 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 XhlA PF10779.9 OWF37428.1 - 7.3 6.9 6.4 1.9 8.7 2.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Lipase_GDSL_2 PF13472.6 OWF37429.1 - 0.00011 22.6 0.0 0.00012 22.5 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF37429.1 - 0.016 15.2 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Oxidored_nitro PF00148.19 OWF37429.1 - 0.022 13.5 0.0 0.24 10.1 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DUF3269 PF11673.8 OWF37429.1 - 0.16 12.3 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) MORN PF02493.20 OWF37430.1 - 1.3e-13 49.9 12.7 5.6e-07 29.1 0.2 4.5 4 0 0 4 4 4 3 MORN repeat RYDR_ITPR PF01365.21 OWF37431.1 - 2.3e-29 102.3 14.0 1.7e-21 76.6 2.9 5.0 4 0 0 4 4 4 2 RIH domain Ins145_P3_rec PF08709.11 OWF37431.1 - 2.3e-22 79.2 0.5 6.5e-20 71.2 1.1 3.0 3 0 0 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 OWF37431.1 - 1.1e-21 76.5 0.4 1.1e-21 76.5 0.4 5.2 6 0 0 6 6 6 1 RyR and IP3R Homology associated MIR PF02815.19 OWF37431.1 - 8e-18 64.9 2.2 2e-13 50.6 0.3 3.5 2 1 0 2 2 2 2 MIR domain Ion_trans PF00520.31 OWF37431.1 - 1e-07 31.4 9.6 1e-07 31.4 9.6 2.1 1 1 1 2 2 2 1 Ion transport protein 5_nucleotid_C PF02872.18 OWF37431.1 - 0.058 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Arm_3 PF16186.5 OWF37431.1 - 0.065 12.8 0.6 3.7 7.2 0.0 3.2 2 0 0 2 2 2 0 Atypical Arm repeat SRCR PF00530.18 OWF37434.1 - 3e-86 284.4 18.2 4e-30 104.3 5.1 3.1 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF37434.1 - 1.3e-19 70.5 7.2 1e-05 25.9 0.2 3.3 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF37434.1 - 5.5e-08 33.3 0.0 0.58 10.7 0.0 3.3 3 0 0 3 3 3 3 Hepsin, SRCR domain FXa_inhibition PF14670.6 OWF37435.1 - 1.7e-31 108.2 125.9 4.1e-08 33.4 8.9 9.5 8 0 0 8 8 8 7 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 OWF37435.1 - 2.2e-27 95.2 14.9 2.2e-06 28.0 0.0 10.2 11 0 0 11 11 11 5 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 OWF37435.1 - 3.3e-17 62.4 100.3 1.9e-08 34.3 8.5 6.4 6 1 1 7 7 7 4 Low-density lipoprotein receptor domain class A cEGF PF12662.7 OWF37435.1 - 8.7e-12 44.7 66.9 1.3e-05 25.0 3.8 10.4 9 0 0 9 9 9 5 Complement Clr-like EGF-like DUF5050 PF16472.5 OWF37435.1 - 1.9e-09 37.2 0.0 0.00032 20.0 0.0 3.5 4 1 0 4 4 4 2 Domain of unknown function (DUF5050) EGF_CA PF07645.15 OWF37435.1 - 1.3e-08 34.9 29.7 4.3e-07 30.0 8.6 12.2 10 1 0 10 10 10 2 Calcium-binding EGF domain SGL PF08450.12 OWF37435.1 - 1e-06 28.5 7.6 8.8 5.8 0.0 7.6 5 2 4 9 9 9 1 SMP-30/Gluconolactonase/LRE-like region EGF PF00008.27 OWF37435.1 - 0.68 10.3 136.4 0.046 14.0 7.9 12.0 11 0 0 11 11 11 0 EGF-like domain FAD_binding_1 PF00667.20 OWF37436.1 - 3.2e-52 177.3 0.1 4.4e-52 176.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OWF37436.1 - 7.9e-34 116.9 0.0 2.3e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 OWF37436.1 - 2.9e-14 53.6 0.0 5.8e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 OWF37436.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain RelE PF06296.12 OWF37436.1 - 0.17 12.0 0.3 0.44 10.7 0.1 1.7 2 0 0 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system Flavodoxin_5 PF12724.7 OWF37436.1 - 0.19 11.9 0.1 1.5 9.0 0.1 2.3 1 1 1 2 2 2 0 Flavodoxin domain PAX PF00292.18 OWF37438.1 - 2e-27 95.6 0.0 3.2e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 OWF37438.1 - 2.2e-24 85.1 2.8 5.4e-24 83.8 2.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF37438.1 - 5.7e-05 22.9 0.0 0.00022 21.1 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 OWF37438.1 - 0.064 13.3 0.8 0.3 11.2 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix Pkinase PF00069.25 OWF37439.1 - 8.6e-46 156.4 0.0 5.1e-26 91.6 0.1 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37439.1 - 5.8e-15 55.3 0.0 3.2e-12 46.3 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OWF37439.1 - 1.6e-05 25.0 0.0 0.0044 17.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OWF37439.1 - 0.069 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CCDC24 PF15669.5 OWF37439.1 - 0.35 10.7 2.0 0.44 10.4 0.6 1.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family BING4CT PF08149.11 OWF37440.1 - 1.2e-37 127.5 0.0 1.3e-35 121.1 0.0 3.3 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 OWF37440.1 - 5.3e-07 30.2 0.5 9.5e-05 23.1 0.0 3.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF37440.1 - 5.3e-06 26.7 0.1 0.62 10.4 0.0 4.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OWF37440.1 - 0.022 13.3 0.0 0.41 9.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain zf-RING_UBOX PF13445.6 OWF37441.1 - 6.3e-11 42.1 2.4 6.3e-11 42.1 2.4 3.1 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF37441.1 - 2.5e-09 36.9 7.5 2.5e-09 36.9 7.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF37441.1 - 3.7e-09 36.3 8.6 3.7e-09 36.3 8.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF37441.1 - 6.9e-09 35.9 7.0 6.9e-09 35.9 7.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF37441.1 - 1.1e-07 31.6 8.2 1.1e-07 31.6 8.2 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF37441.1 - 2.9e-07 30.3 6.0 2.9e-07 30.3 6.0 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF37441.1 - 4e-06 26.9 9.6 4e-06 26.9 9.6 3.3 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF37441.1 - 4.4e-06 26.5 6.7 4.4e-06 26.5 6.7 3.0 2 2 2 4 4 3 1 Prokaryotic RING finger family 4 NHL PF01436.21 OWF37441.1 - 2.9e-05 23.9 0.2 0.091 12.8 0.0 3.2 3 0 0 3 3 3 2 NHL repeat zf-RING_4 PF14570.6 OWF37441.1 - 0.072 12.9 23.1 0.03 14.1 6.2 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 OWF37441.1 - 0.14 12.3 15.8 0.081 13.1 4.2 2.7 2 1 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 OWF37441.1 - 0.57 10.4 12.8 0.87 9.8 0.6 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger LRAT PF04970.13 OWF37442.1 - 4.9e-19 68.9 0.1 8.7e-19 68.1 0.1 1.4 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Z1 PF10593.9 OWF37442.1 - 0.036 13.6 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Z1 domain LRAT PF04970.13 OWF37443.1 - 2.7e-30 105.3 0.0 3.5e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF37443.1 - 8.3e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family LRAT PF04970.13 OWF37444.1 - 1.2e-30 106.4 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF37444.1 - 0.00077 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family LRAT PF04970.13 OWF37445.1 - 1.4e-28 99.8 0.0 1.7e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF37445.1 - 0.0081 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C97 PF05903.14 OWF37445.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain ComS PF17584.2 OWF37445.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacillus competence protein S Y_phosphatase PF00102.27 OWF37446.1 - 1.2e-132 440.7 3.7 2e-72 243.6 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 OWF37446.1 - 4.1e-47 158.4 14.8 3e-12 46.7 0.0 6.2 6 0 0 6 6 6 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF37446.1 - 5.3e-11 42.9 11.0 0.0012 19.4 0.6 5.5 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 OWF37446.1 - 2.8e-06 27.2 0.1 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Interfer-bind PF09294.10 OWF37446.1 - 8.3e-05 22.9 0.6 0.16 12.3 0.0 4.3 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III SKG6 PF08693.10 OWF37446.1 - 0.0032 16.8 5.1 0.0065 15.9 5.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2369 PF10179.9 OWF37446.1 - 0.0036 17.7 0.1 0.22 11.9 0.0 3.8 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 OWF37446.1 - 0.0079 16.7 0.4 0.59 10.7 0.2 3.1 3 0 0 3 3 2 1 PhoD-like phosphatase, N-terminal domain Stevor PF17410.2 OWF37446.1 - 0.0079 15.8 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 OWF37446.1 - 0.0094 15.9 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Rifin Y_Y_Y PF07495.13 OWF37446.1 - 0.0094 15.9 4.5 1 9.3 0.8 2.8 2 0 0 2 2 2 2 Y_Y_Y domain Y_phosphatase3 PF13350.6 OWF37446.1 - 0.0096 15.9 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family CD34_antigen PF06365.12 OWF37446.1 - 0.063 12.9 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Myotub-related PF06602.14 OWF37446.1 - 0.073 12.0 0.0 6.5 5.6 0.0 2.5 2 1 0 2 2 2 0 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.13 OWF37446.1 - 0.08 12.5 0.0 8.6 5.9 0.0 2.7 2 0 0 2 2 2 0 Tyrosine phosphatase family EphA2_TM PF14575.6 OWF37446.1 - 0.093 13.6 0.0 0.25 12.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 OWF37446.1 - 0.12 12.3 0.4 0.42 10.6 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) OppC_N PF12911.7 OWF37446.1 - 1.6 8.7 3.3 8.5 6.4 0.2 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C SRCR PF00530.18 OWF37447.1 - 5.1e-46 155.3 11.5 2.7e-23 82.3 2.3 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 OWF37447.1 - 2e-41 142.5 9.8 3.4e-41 141.8 9.8 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR_2 PF15494.6 OWF37447.1 - 2.9e-08 34.1 2.5 0.00081 19.9 1.2 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF37447.1 - 0.0039 17.7 2.2 0.18 12.3 0.7 2.6 2 0 0 2 2 2 1 Hepsin, SRCR domain SRCR PF00530.18 OWF37448.1 - 1.2e-49 166.9 11.8 1.3e-27 96.2 2.5 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 OWF37448.1 - 4.7e-37 128.2 10.4 7.4e-37 127.5 10.4 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR_2 PF15494.6 OWF37448.1 - 1.9e-09 37.9 1.0 0.00077 19.9 0.4 3.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF37448.1 - 0.021 15.3 1.4 1.3 9.6 0.3 2.8 2 0 0 2 2 2 0 Hepsin, SRCR domain FXR_C1 PF16096.5 OWF37448.1 - 0.27 11.5 8.2 3.1 8.0 4.8 2.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Notch PF00066.17 OWF37448.1 - 1.7 9.1 5.8 1.1 9.7 2.4 2.6 2 0 0 2 2 2 0 LNR domain Vert_HS_TF PF06546.11 OWF37448.1 - 6.2 6.4 11.3 5.4 6.6 9.3 1.8 2 0 0 2 2 2 0 Vertebrate heat shock transcription factor WD40 PF00400.32 OWF37449.1 - 1.9e-58 193.1 24.1 7.5e-11 42.4 0.7 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF37449.1 - 2.5e-18 66.1 3.3 0.00094 19.4 0.0 5.6 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF37449.1 - 4.7e-08 32.4 2.3 0.057 12.4 0.0 4.7 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OWF37449.1 - 1.7e-05 24.3 0.0 3.6 6.8 0.0 4.5 1 1 5 6 6 6 2 WD40-like domain PD40 PF07676.12 OWF37449.1 - 0.0004 20.2 2.0 45 4.1 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OWF37449.1 - 0.0015 17.2 3.0 0.023 13.3 0.1 3.1 3 2 0 3 3 3 1 Nucleoporin Nup120/160 zf-C2H2 PF00096.26 OWF37450.1 - 4.3e-14 52.1 18.4 5.7e-05 23.3 1.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF37450.1 - 6.8e-14 51.6 14.4 2.8e-07 30.6 1.3 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF37450.1 - 1.9e-12 46.9 13.4 0.00038 21.1 2.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger SET PF00856.28 OWF37450.1 - 6.6e-08 33.1 0.0 2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-C2H2_jaz PF12171.8 OWF37450.1 - 1.2e-07 31.9 7.1 0.0016 18.7 0.0 3.7 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF37450.1 - 2.8e-07 30.7 13.1 0.0002 21.7 0.1 3.6 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OWF37450.1 - 1.3e-06 28.7 5.9 0.07 13.5 0.1 3.3 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OWF37450.1 - 0.00095 19.1 9.4 0.05 13.6 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 OWF37450.1 - 0.0016 18.7 3.2 0.0054 17.0 0.5 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 OWF37450.1 - 0.01 15.9 11.9 0.43 10.6 0.5 3.3 1 1 2 3 3 3 0 BED zinc finger Elf1 PF05129.13 OWF37450.1 - 0.045 13.8 1.0 0.045 13.8 1.0 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DDE_Tnp_IS240 PF13610.6 OWF37450.1 - 0.062 13.5 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 DDE domain zf-C2HE PF16278.5 OWF37450.1 - 0.11 13.0 5.7 23 5.5 0.7 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zf_RING PF16744.5 OWF37450.1 - 0.14 12.3 8.6 12 6.1 0.2 3.2 1 1 2 3 3 3 0 KIAA1045 RING finger zf-H2C2_5 PF13909.6 OWF37450.1 - 0.14 11.9 14.4 0.16 11.8 0.8 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HypA PF01155.19 OWF37450.1 - 0.63 10.1 3.2 2.5 8.2 3.2 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 OWF37450.1 - 2.4 8.2 5.2 13 5.8 1.6 2.8 1 1 1 2 2 2 0 zinc-ribbons zf-Sec23_Sec24 PF04810.15 OWF37450.1 - 2.7 8.1 7.4 54 4.0 4.8 3.0 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zf-AN1 PF01428.16 OWF37450.1 - 2.9 8.1 7.4 1.3 9.3 0.3 2.9 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2H2_11 PF16622.5 OWF37450.1 - 5 7.0 18.2 0.15 11.9 2.5 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type CUB PF00431.20 OWF37451.1 - 2.7e-13 50.2 0.5 5.2e-10 39.6 0.0 2.5 2 1 0 2 2 2 2 CUB domain PSP94 PF05825.11 OWF37451.1 - 5.1 7.7 11.3 7.5 7.2 0.2 3.2 3 1 0 3 3 3 0 Beta-microseminoprotein (PSP-94) YbfN PF13982.6 OWF37452.1 - 0.035 14.4 0.9 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 YbfN-like lipoprotein DUF5043 PF16446.5 OWF37452.1 - 0.042 13.8 0.4 0.046 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) T2SSF PF00482.23 OWF37452.1 - 0.048 13.6 0.9 0.069 13.1 0.9 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF3972 PF13118.6 OWF37452.1 - 0.054 13.9 5.5 0.079 13.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) APG6_N PF17675.1 OWF37452.1 - 0.085 13.4 10.5 0.078 13.5 8.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CREPT PF16566.5 OWF37452.1 - 0.096 12.9 8.5 0.12 12.5 7.7 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Spc7 PF08317.11 OWF37452.1 - 0.14 11.0 12.3 0.25 10.2 12.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Ca_chan_IQ PF08763.11 OWF37452.1 - 0.17 12.1 2.5 0.47 10.7 0.2 2.0 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain DUF4200 PF13863.6 OWF37452.1 - 0.18 12.2 12.4 0.073 13.5 9.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.8 OWF37452.1 - 0.21 11.7 11.4 0.34 11.0 11.4 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 OWF37452.1 - 0.22 11.4 8.4 0.35 10.7 8.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FapA PF03961.13 OWF37452.1 - 0.25 9.9 6.3 0.27 9.8 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3450 PF11932.8 OWF37452.1 - 0.28 10.4 8.6 0.45 9.8 8.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CorA PF01544.18 OWF37452.1 - 0.41 9.9 3.9 0.47 9.7 3.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF5320 PF17253.2 OWF37452.1 - 0.54 11.4 4.0 0.18 12.9 0.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) KxDL PF10241.9 OWF37452.1 - 0.73 10.2 8.9 0.25 11.6 3.8 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein TMPIT PF07851.13 OWF37452.1 - 2.6 7.2 7.0 2.8 7.1 7.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein CARD PF00619.21 OWF37453.1 - 1.9e-19 69.5 0.7 3.6e-19 68.6 0.7 1.5 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF37453.1 - 0.00026 20.9 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Bac_RepA_C PF18008.1 OWF37454.1 - 0.13 12.6 0.0 8.2 6.9 0.0 2.5 3 0 0 3 3 3 0 Replication initiator protein A C-terminal domain CDP-OH_P_transf PF01066.21 OWF37455.1 - 1.5e-14 54.5 1.9 1.5e-14 54.5 1.9 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3099 PF11298.8 OWF37455.1 - 1.6 8.9 4.6 0.56 10.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Cu2_monoox_C PF03712.15 OWF37456.1 - 4.3e-27 94.6 0.3 7.4e-27 93.8 0.3 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF37456.1 - 2.2e-23 82.9 0.0 4.4e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Hep_59 PF07052.11 OWF37457.1 - 9.9e-30 103.4 5.4 9.9e-30 103.4 5.4 2.5 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Ribosom_S12_S23 PF00164.25 OWF37457.1 - 0.029 14.0 0.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S12/S23 SIR4_SID PF16991.5 OWF37457.1 - 2.3 8.2 10.9 1.7 8.6 3.7 3.1 1 1 1 2 2 2 0 Sir4 SID domain DNA_gyraseA_C PF03989.13 OWF37458.1 - 0.017 14.6 1.4 7.8 6.1 0.1 3.2 1 1 2 3 3 3 0 DNA gyrase C-terminal domain, beta-propeller PH_8 PF15409.6 OWF37458.1 - 0.023 15.0 2.2 1.9 8.8 0.5 2.5 1 1 2 3 3 3 0 Pleckstrin homology domain Cadherin_3 PF16184.5 OWF37458.1 - 0.045 13.8 1.0 0.55 10.3 0.6 2.1 1 1 1 2 2 2 0 Cadherin-like Tcp10_C PF07202.13 OWF37458.1 - 0.056 13.4 2.3 0.78 9.7 2.3 2.2 1 1 0 1 1 1 0 T-complex protein 10 C-terminus M157 PF11624.8 OWF37458.1 - 0.15 11.3 2.2 2.9 7.1 1.8 2.5 1 1 0 1 1 1 0 MHC class I-like protein M157 Cu_amine_oxidN1 PF07833.11 OWF37458.1 - 0.2 12.1 1.9 0.61 10.6 1.9 1.8 1 1 0 1 1 1 0 Copper amine oxidase N-terminal domain dUTPase PF00692.19 OWF37458.1 - 0.52 10.0 6.0 7.1 6.3 0.5 2.8 1 1 2 3 3 3 0 dUTPase MCPVI PF02993.14 OWF37458.1 - 6.5 6.5 7.5 8 6.2 0.9 2.1 1 1 1 2 2 2 0 Minor capsid protein VI Ion_trans PF00520.31 OWF37459.1 - 6e-102 340.0 26.4 4.2e-64 216.1 20.0 2.1 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 OWF37459.1 - 2.2e-29 101.0 0.1 4.6e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 OWF37459.1 - 8e-28 96.5 0.1 1.6e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 OWF37459.1 - 1.3e-10 40.6 14.4 1.3e-10 40.6 14.4 3.7 3 1 0 3 3 3 1 Polycystin cation channel Ion_trans PF00520.31 OWF37460.1 - 4.8e-131 435.3 47.3 2.6e-65 220.1 10.0 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 OWF37460.1 - 2.5e-07 29.7 41.7 7.4e-07 28.2 5.2 5.0 3 2 2 5 5 5 3 Polycystin cation channel RNase_P_p30 PF01876.16 OWF37463.1 - 0.00019 21.0 0.5 36 3.7 0.0 5.0 2 2 3 5 5 5 1 RNase P subunit p30 RICTOR_V PF14668.6 OWF37463.1 - 0.00024 21.3 1.5 33 4.8 0.0 5.2 1 1 3 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Tet_res_leader PF08050.12 OWF37463.1 - 0.0019 18.0 4.3 3.6e+02 1.1 0.0 8.9 12 0 0 12 12 12 0 Tetracycline resistance leader peptide DUF4573 PF15140.6 OWF37463.1 - 0.0062 16.4 5.6 0.014 15.2 1.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4573) DUF3372 PF11852.8 OWF37463.1 - 0.13 11.7 3.5 22 4.5 0.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3372) Ank_2 PF12796.7 OWF37464.1 - 3.1e-42 143.1 0.2 6.7e-15 55.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF37464.1 - 6.7e-36 122.2 5.5 1.7e-13 50.8 0.0 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37464.1 - 9.2e-35 118.3 7.9 7.8e-09 35.6 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF37464.1 - 1.4e-29 101.2 2.8 1.6e-05 25.2 0.1 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 OWF37464.1 - 4.8e-29 97.2 2.5 0.00023 21.4 0.0 7.3 6 0 0 6 6 6 6 Ankyrin repeat SET PF00856.28 OWF37464.1 - 3.2e-21 76.5 0.7 1.9e-20 74.0 0.1 2.7 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 OWF37464.1 - 2.3e-15 57.2 7.4 2.3e-15 57.2 7.4 3.4 3 1 0 3 3 3 1 Pre-SET motif Kinesin PF00225.23 OWF37465.1 - 1.2e-95 320.3 0.0 1.2e-95 320.3 0.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OWF37465.1 - 7.6e-18 64.9 1.0 4.8e-17 62.3 0.0 2.8 3 0 0 3 3 3 1 Microtubule binding Yop-YscD_cpl PF16697.5 OWF37465.1 - 4.4e-05 23.7 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 OWF37465.1 - 4.7e-05 23.7 1.7 4.7e-05 23.7 1.7 3.9 4 0 0 4 4 4 1 Kinesin protein 1B FHA PF00498.26 OWF37465.1 - 0.00091 19.5 0.0 0.0026 18.1 0.0 1.8 1 0 0 1 1 1 1 FHA domain Kinesin_assoc PF16183.5 OWF37465.1 - 0.015 15.5 19.8 0.035 14.3 2.8 4.4 3 2 1 4 4 4 0 Kinesin-associated DUF5118 PF17162.4 OWF37465.1 - 0.091 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) DUF1318 PF07027.12 OWF37465.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1318) Sema PF01403.19 OWF37466.1 - 8.1e-110 367.5 0.1 8.1e-110 367.5 0.1 1.9 2 0 0 2 2 2 1 Sema domain TSP_1 PF00090.19 OWF37466.1 - 1.3e-41 140.6 95.0 1.2e-10 41.4 6.0 7.7 7 1 0 7 7 7 6 Thrombospondin type 1 domain DUF5410 PF17422.2 OWF37467.1 - 1.3e-06 28.0 4.5 2.2 7.5 0.1 5.1 1 1 4 5 5 5 5 Family of unknown function (DUF5410) WD40 PF00400.32 OWF37468.1 - 6.2e-09 36.4 0.3 1.6e-05 25.6 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF37468.1 - 4.1e-05 23.8 0.0 0.043 14.1 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3196 PF11428.8 OWF37468.1 - 0.00052 19.6 0.2 0.00093 18.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3196) LisH_TPL PF17814.1 OWF37468.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Suppressor_APC PF11414.8 OWF37468.1 - 0.093 12.8 6.1 0.23 11.5 6.1 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein WD40 PF00400.32 OWF37469.1 - 1.6e-14 54.0 6.3 0.0018 19.0 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF37469.1 - 4.4e-05 23.7 0.0 0.0057 16.9 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OWF37469.1 - 0.029 12.7 0.0 0.41 8.9 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz NHL PF01436.21 OWF37469.1 - 0.14 12.2 0.7 16 5.7 0.1 3.1 3 0 0 3 3 3 0 NHL repeat RRM_1 PF00076.22 OWF37470.1 - 1.2e-11 44.2 1.2 2.4e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF37470.1 - 0.00087 19.3 0.0 0.00087 19.3 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 OWF37470.1 - 0.0028 17.6 0.0 0.006 16.6 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PGM_PMM_II PF02879.16 OWF37470.1 - 0.011 16.4 0.3 0.096 13.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II RRM_occluded PF16842.5 OWF37470.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif TGT PF01702.18 OWF37471.1 - 1.1e-84 284.6 0.0 1.3e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF1722 PF08349.11 OWF37471.1 - 0.021 15.1 0.9 0.2 11.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF5362 PF17319.2 OWF37471.1 - 0.068 13.0 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5362) Pkinase PF00069.25 OWF37474.1 - 2e-62 210.9 0.0 4.6e-62 209.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37474.1 - 1.4e-40 139.3 0.0 5.5e-40 137.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.16 OWF37474.1 - 9.3e-39 131.4 37.4 4.2e-16 58.8 2.0 4.4 3 1 1 4 4 4 3 Hr1 repeat Kinase-like PF14531.6 OWF37474.1 - 1.2e-08 34.6 0.0 1.5e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OWF37474.1 - 2.1e-08 34.8 1.3 5e-08 33.5 0.1 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Uds1 PF15456.6 OWF37474.1 - 1.8e-05 24.9 20.1 0.035 14.3 0.2 3.5 2 1 1 3 3 3 3 Up-regulated During Septation PTPlike_phytase PF14566.6 OWF37474.1 - 0.067 13.3 0.6 0.32 11.1 0.6 2.1 1 0 0 1 1 1 0 Inositol hexakisphosphate cwf21 PF08312.12 OWF37474.1 - 0.094 12.9 2.6 0.34 11.1 0.1 3.2 3 0 0 3 3 3 0 cwf21 domain DUF1658 PF07871.11 OWF37475.1 - 0.046 13.7 3.8 0.046 13.7 3.8 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1658) TruB_N PF01509.18 OWF37477.1 - 8.3e-13 48.9 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) HAD_2 PF13419.6 OWF37479.1 - 4.4e-18 66.0 0.0 6.1e-18 65.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OWF37479.1 - 3.3e-11 43.9 0.0 4.4e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OWF37479.1 - 5.8e-06 26.3 0.0 9.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OWF37479.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DrrA_P4M PF14860.6 OWF37479.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain LRR_9 PF14580.6 OWF37480.1 - 1.8e-18 66.6 4.8 1.8e-18 66.6 4.8 3.6 3 1 1 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 OWF37480.1 - 1.5e-11 44.3 15.3 3.9e-06 27.1 1.4 4.0 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF37480.1 - 6.1e-09 35.5 13.3 1.3e-06 28.0 5.6 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OWF37480.1 - 1.5 9.0 9.9 2.5 8.4 0.1 4.7 3 1 1 4 4 4 0 Leucine Rich repeat FMO-like PF00743.19 OWF37481.1 - 3.5e-27 95.0 0.0 3.7e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FMO-like PF00743.19 OWF37482.1 - 1.2e-108 363.9 0.0 1.3e-108 363.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF37482.1 - 0.084 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 OWF37483.1 - 2.2e-08 34.2 0.2 2.9e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Glutaredoxin EGF_CA PF07645.15 OWF37484.1 - 1.3e-07 31.7 9.4 1.3e-07 31.7 9.4 3.8 4 1 0 4 4 4 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF37484.1 - 0.00025 21.3 10.9 0.00025 21.3 10.9 3.5 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF37484.1 - 0.0023 17.8 1.4 0.0023 17.8 1.4 3.7 4 1 0 4 4 4 1 Complement Clr-like EGF-like DUF4988 PF16378.5 OWF37484.1 - 0.1 12.2 0.3 0.29 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF2057 PF09829.9 OWF37484.1 - 0.2 11.8 2.3 0.3 11.3 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SSP160 PF06933.11 OWF37484.1 - 2.7 6.1 20.9 4.2 5.4 20.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 OWF37484.1 - 6 6.9 34.4 7 6.6 34.4 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein RICH PF05062.12 OWF37486.1 - 0.077 13.4 0.0 0.083 13.2 0.0 1.1 1 0 0 1 1 1 0 RICH domain Pkinase PF00069.25 OWF37487.1 - 2.3e-25 89.4 0.0 6.6e-25 88.0 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37487.1 - 1.2e-15 57.5 0.0 6.1e-15 55.2 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OWF37489.1 - 7.8e-73 245.1 0.0 1e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37489.1 - 1.1e-38 133.0 0.0 1.5e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OWF37489.1 - 4.3e-13 48.8 0.0 8.1e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OWF37489.1 - 5.5e-08 32.5 0.0 9.6e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF37489.1 - 0.00016 21.1 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF37489.1 - 0.0024 16.9 0.1 0.0037 16.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF37489.1 - 0.005 16.8 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OWF37489.1 - 0.0093 15.6 0.0 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 OWF37490.1 - 2.5e-49 168.0 0.0 3.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37490.1 - 1e-33 116.7 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF37490.1 - 1.2e-08 34.6 0.0 2.4e-08 33.6 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OWF37490.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OWF37490.1 - 0.013 14.5 0.3 0.035 13.1 0.3 1.7 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase Nucleoplasmin PF03066.15 OWF37491.1 - 0.0012 19.3 2.7 63 4.1 0.0 5.3 1 1 5 6 6 6 0 Nucleoplasmin/nucleophosmin domain Agglutinin PF07468.11 OWF37491.1 - 0.0086 16.3 0.0 17 5.6 0.0 3.1 1 1 2 3 3 3 2 Agglutinin domain DUF2993 PF11209.8 OWF37491.1 - 0.032 14.5 1.9 22 5.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2993) LBP_BPI_CETP_C PF02886.17 OWF37491.1 - 0.054 12.9 0.0 2.1 7.7 0.0 2.0 1 1 1 2 2 2 0 LBP / BPI / CETP family, C-terminal domain BpuSI_N PF15516.6 OWF37491.1 - 0.09 12.7 0.0 32 4.4 0.0 3.2 1 1 3 4 4 4 0 BpuSI N-terminal domain bPH_5 PF10882.8 OWF37492.1 - 0.00021 21.3 3.6 8.2 6.6 0.1 6.1 2 2 5 8 8 8 2 Bacterial PH domain DUF3152 PF11350.8 OWF37492.1 - 2.3 7.9 14.1 28 4.3 0.2 5.1 1 1 2 5 5 5 0 Protein of unknown function (DUF3152) Pentapeptide PF00805.22 OWF37493.1 - 0.02 14.5 0.0 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) FLgD_tudor PF13861.6 OWF37493.1 - 0.034 14.4 2.7 7.2 6.9 2.7 3.6 1 1 0 1 1 1 0 FlgD Tudor-like domain Zfx_Zfy_act PF04704.13 OWF37493.1 - 0.12 11.4 3.9 0.56 9.3 3.9 1.9 1 1 0 1 1 1 0 Zfx / Zfy transcription activation region ATP-synt_ab_Xtn PF16886.5 OWF37493.1 - 0.38 10.6 3.7 13 5.7 0.1 2.8 1 1 2 3 3 3 0 ATPsynthase alpha/beta subunit N-term extension Acetyltransf_3 PF13302.7 OWF37494.1 - 2.1e-27 96.5 0.0 2.5e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF37494.1 - 2.9e-07 30.7 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OWF37494.1 - 5.9e-07 29.4 0.0 9.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 OWF37494.1 - 7.5e-07 28.9 0.6 1.4e-05 24.8 0.6 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OWF37494.1 - 4.4e-05 23.7 0.2 7.6e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF37494.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF37494.1 - 0.0038 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TSP_1 PF00090.19 OWF37495.1 - 3.8e-26 91.1 112.6 8.9e-10 38.6 7.3 12.3 10 1 1 11 11 10 8 Thrombospondin type 1 domain Reprolysin PF01421.19 OWF37495.1 - 6.9e-19 68.5 0.6 2e-18 67.0 0.6 1.9 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_spacer1 PF05986.14 OWF37495.1 - 2.5e-18 66.2 0.0 4.1e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 OWF37495.1 - 7e-14 52.1 10.4 7e-14 52.1 10.4 6.6 6 1 0 6 6 3 2 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 OWF37495.1 - 1e-13 51.7 0.5 6.6e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_3 PF13582.6 OWF37495.1 - 2.2e-12 47.6 0.1 7.7e-12 45.8 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF37495.1 - 9.3e-12 45.5 0.9 3.6e-11 43.6 0.9 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OWF37495.1 - 4.8e-08 33.1 0.7 4.8e-08 33.1 0.7 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF37495.1 - 1.9e-06 27.7 0.9 5.1e-06 26.3 0.9 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF37495.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin PLAC PF08686.11 OWF37495.1 - 0.25 12.1 10.5 4 8.3 10.5 3.4 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain Claudin_2 PF13903.6 OWF37496.1 - 2.4e-15 56.8 3.8 3.2e-15 56.4 3.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF37496.1 - 0.0032 17.3 6.5 0.015 15.2 6.5 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Neur_chan_LBD PF02931.23 OWF37498.1 - 1e-64 218.0 1.3 1.3e-64 217.6 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF37498.1 - 9.2e-34 117.5 1.2 1.3e-33 117.0 0.3 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF1706 PF08020.11 OWF37498.1 - 0.011 15.6 1.8 0.33 10.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1706) PuR_N PF09182.10 OWF37498.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Spc7 PF08317.11 OWF37499.1 - 1.7e-13 50.2 37.1 6.8e-05 21.9 8.9 4.3 1 1 3 4 4 4 4 Spc7 kinetochore protein GCN5L1 PF06320.13 OWF37499.1 - 5.4e-11 42.6 18.6 0.088 13.0 2.8 5.1 1 1 4 5 5 5 5 GCN5-like protein 1 (GCN5L1) Laminin_II PF06009.12 OWF37499.1 - 1.8e-10 41.0 9.2 0.047 13.7 0.2 5.0 1 1 4 5 5 5 4 Laminin Domain II V-SNARE PF05008.15 OWF37499.1 - 3.8e-10 40.0 4.3 0.62 10.5 0.2 6.3 1 1 4 5 5 5 3 Vesicle transport v-SNARE protein N-terminus EzrA PF06160.12 OWF37499.1 - 7e-10 37.7 19.1 2.9e-09 35.7 17.8 2.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 OWF37499.1 - 7.5e-10 39.1 7.3 0.00092 19.6 0.2 4.2 1 1 3 5 5 5 3 Snapin/Pallidin Seryl_tRNA_N PF02403.22 OWF37499.1 - 1.2e-09 38.4 14.7 0.0089 16.2 0.3 4.6 1 1 2 3 3 3 2 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 OWF37499.1 - 2.5e-09 37.6 10.1 0.0062 16.8 0.8 3.2 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OWF37499.1 - 1.6e-08 35.2 46.0 0.0062 17.0 12.8 4.2 1 1 2 3 3 3 2 Fez1 KELK PF15796.5 OWF37499.1 - 2.3e-07 31.1 36.4 0.046 14.2 3.4 5.6 1 1 5 6 6 6 5 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 OWF37499.1 - 1.4e-06 28.3 28.5 0.34 11.0 2.3 6.0 1 1 5 6 6 6 4 Protein of unknown function (DUF1664) IFT57 PF10498.9 OWF37499.1 - 1.5e-06 27.5 35.7 0.0031 16.5 12.1 2.3 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Occludin_ELL PF07303.13 OWF37499.1 - 3.3e-06 27.7 28.3 0.67 10.7 6.5 6.0 1 1 4 5 5 5 2 Occludin homology domain TMPIT PF07851.13 OWF37499.1 - 9.5e-06 25.1 49.8 0.036 13.3 9.7 4.4 1 1 3 4 4 4 2 TMPIT-like protein MCPsignal PF00015.21 OWF37499.1 - 1.1e-05 25.4 12.3 0.093 12.5 1.3 3.8 1 1 3 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_13 PF13166.6 OWF37499.1 - 1.1e-05 24.4 30.4 0.0032 16.2 8.2 3.2 1 1 2 3 3 3 3 AAA domain CALCOCO1 PF07888.11 OWF37499.1 - 1.4e-05 24.2 34.8 7.8e-05 21.7 13.6 2.1 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like DLP_helical PF18709.1 OWF37499.1 - 3.2e-05 23.3 13.7 1.3 8.1 0.7 4.8 1 1 3 4 4 4 3 Dynamin-like helical domain DUF641 PF04859.12 OWF37499.1 - 3.5e-05 24.1 34.0 0.49 10.7 1.3 5.3 1 1 4 5 5 5 4 Plant protein of unknown function (DUF641) HrpB7 PF09486.10 OWF37499.1 - 4.4e-05 23.9 25.9 3.5 8.0 0.4 7.0 1 1 5 6 6 6 0 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 OWF37499.1 - 5.7e-05 22.8 29.1 0.56 9.7 16.2 4.2 1 1 1 2 2 2 2 Intermediate filament protein DUF745 PF05335.13 OWF37499.1 - 8.3e-05 22.4 16.9 0.14 11.8 2.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF745) MobC PF05713.11 OWF37499.1 - 0.00011 22.6 6.6 8.1 7.0 0.1 8.2 1 1 9 10 10 10 0 Bacterial mobilisation protein (MobC) BRE1 PF08647.11 OWF37499.1 - 0.00022 21.2 12.6 0.11 12.5 1.2 3.9 1 1 3 4 4 4 2 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 OWF37499.1 - 0.00029 20.9 19.2 0.0093 16.0 5.3 3.2 1 1 4 5 5 5 4 TPR/MLP1/MLP2-like protein KxDL PF10241.9 OWF37499.1 - 0.00031 21.0 8.3 4.8 7.5 0.1 5.1 1 1 4 5 5 5 0 Uncharacterized conserved protein THOC7 PF05615.13 OWF37499.1 - 0.00079 19.7 20.7 0.024 14.9 2.0 4.0 1 1 3 4 4 4 3 Tho complex subunit 7 GAS PF13851.6 OWF37499.1 - 0.00079 18.8 26.8 0.012 15.0 5.3 3.4 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding T3SSipB PF16535.5 OWF37499.1 - 0.0014 19.1 1.1 20 5.6 0.1 4.1 1 1 2 3 3 3 0 Type III cell invasion protein SipB FliJ PF02050.16 OWF37499.1 - 0.0015 18.8 4.2 4.3 7.6 0.0 4.7 1 1 3 4 4 4 0 Flagellar FliJ protein DUF4200 PF13863.6 OWF37499.1 - 0.0028 18.1 30.5 1.9 8.9 4.6 4.6 1 1 3 4 4 4 2 Domain of unknown function (DUF4200) HsbA PF12296.8 OWF37499.1 - 0.0037 17.7 0.0 13 6.3 0.0 3.4 2 1 2 4 4 3 0 Hydrophobic surface binding protein A APG17 PF04108.12 OWF37499.1 - 0.0043 16.2 39.1 0.18 10.9 7.8 3.8 1 1 2 3 3 3 2 Autophagy protein Apg17 PspA_IM30 PF04012.12 OWF37499.1 - 0.0094 15.6 1.8 2.9 7.4 0.1 3.5 1 1 3 4 4 4 1 PspA/IM30 family LPP PF04728.13 OWF37499.1 - 0.019 15.3 0.0 1.4e+02 2.9 0.0 4.8 1 1 5 6 6 5 0 Lipoprotein leucine-zipper Phage_HK97_TLTM PF06120.11 OWF37499.1 - 0.03 13.5 14.4 2.7 7.1 1.9 3.9 1 1 3 4 4 4 0 Tail length tape measure protein Golgin_A5 PF09787.9 OWF37499.1 - 0.038 13.5 37.4 1.5 8.2 13.2 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF3450 PF11932.8 OWF37499.1 - 0.042 13.2 0.1 10 5.3 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 OWF37499.1 - 0.043 14.1 9.5 5.4 7.3 0.2 4.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.9 OWF37499.1 - 0.05 13.8 10.9 2.5 8.3 0.6 3.8 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Cnn_1N PF07989.11 OWF37499.1 - 0.051 13.7 37.4 3.2 8.0 1.1 7.4 1 1 5 6 6 5 0 Centrosomin N-terminal motif 1 YscO PF07321.12 OWF37499.1 - 0.14 12.1 36.2 2.8 7.9 2.6 5.6 1 1 5 6 6 6 0 Type III secretion protein YscO Img2 PF05046.14 OWF37499.1 - 0.25 11.6 17.0 5.4 7.4 0.4 5.0 1 1 3 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) PI3K_P85_iSH2 PF16454.5 OWF37499.1 - 0.26 10.8 28.0 4.4 6.9 6.2 4.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain WEMBL PF05701.11 OWF37499.1 - 0.37 9.4 32.9 0.77 8.4 31.9 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Laminin_I PF06008.14 OWF37499.1 - 0.44 10.2 5.5 2.8 7.6 3.8 2.5 1 1 1 2 2 2 0 Laminin Domain I DUF4201 PF13870.6 OWF37499.1 - 0.45 10.2 39.8 0.59 9.8 13.6 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) ERM PF00769.19 OWF37499.1 - 0.53 10.0 28.9 0.091 12.6 7.8 2.7 1 1 2 3 3 3 0 Ezrin/radixin/moesin family CENP-H PF05837.12 OWF37499.1 - 0.56 10.6 21.8 11 6.4 0.8 4.7 1 1 2 3 3 3 0 Centromere protein H (CENP-H) ZapB PF06005.12 OWF37499.1 - 0.76 10.3 14.9 10 6.7 0.9 4.8 2 1 1 3 3 3 0 Cell division protein ZapB ADIP PF11559.8 OWF37499.1 - 0.84 9.7 25.5 2 8.5 5.8 3.8 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Med4 PF10018.9 OWF37499.1 - 0.85 9.3 40.4 21 4.7 2.2 6.1 1 1 3 4 4 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1515 PF07439.11 OWF37499.1 - 1.2 9.1 11.7 14 5.8 1.0 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1515) DegS PF05384.11 OWF37499.1 - 1.3 8.5 27.0 28 4.2 14.8 4.1 1 1 2 3 3 3 0 Sensor protein DegS DUF812 PF05667.11 OWF37499.1 - 1.3 7.8 34.6 28 3.4 16.9 4.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Syntaxin-6_N PF09177.11 OWF37499.1 - 1.4 9.5 16.5 69 4.1 7.2 4.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HemX PF04375.14 OWF37499.1 - 1.5 8.0 3.0 52 3.0 3.0 2.7 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase YkyA PF10368.9 OWF37499.1 - 2.5 7.7 15.9 4.9 6.8 8.9 2.4 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein AcylCoA_dehyd_C PF12186.8 OWF37499.1 - 3 8.0 31.1 4 7.6 1.2 6.7 1 1 6 7 7 7 0 Acyl-CoA dehydrogenase C terminal HAP1_N PF04849.13 OWF37499.1 - 3.6 6.7 50.9 0.32 10.2 17.6 3.0 1 1 3 4 4 4 0 HAP1 N-terminal conserved region PLA2G12 PF06951.11 OWF37500.1 - 1.2e-38 132.8 13.1 1.4e-38 132.6 13.1 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Noggin PF05806.12 OWF37501.1 - 5.6e-70 235.6 6.3 7e-70 235.3 6.3 1.0 1 0 0 1 1 1 1 Noggin Noggin PF05806.12 OWF37502.1 - 3.7e-44 151.2 6.1 4.9e-44 150.8 6.1 1.1 1 0 0 1 1 1 1 Noggin Perilipin PF03036.16 OWF37503.1 - 0.73 8.8 1.5 7.3 5.5 0.0 2.3 1 1 0 2 2 2 0 Perilipin family Tetraspanin PF00335.20 OWF37504.1 - 1.1e-55 188.8 9.6 1.4e-55 188.5 9.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2754 PF10953.8 OWF37504.1 - 0.058 13.6 1.3 0.058 13.6 1.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2754) Neurensin PF14927.6 OWF37504.1 - 0.44 10.2 7.9 0.69 9.6 0.0 2.9 2 1 1 3 3 3 0 Neurensin Colicin_K PF17500.2 OWF37505.1 - 0.045 14.3 0.5 0.13 12.8 0.5 1.8 1 0 0 1 1 1 0 Colicin-K DUF2046 PF09755.9 OWF37506.1 - 2.3e-152 506.5 54.7 2.9e-152 506.2 54.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 OWF37506.1 - 0.22 11.8 58.3 1.3 9.2 24.4 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 OWF37506.1 - 2.3 7.2 49.5 0.33 10.0 8.6 3.1 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 U-box PF04564.15 OWF37507.1 - 4.4e-27 94.0 0.0 9.1e-27 93.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 OWF37507.1 - 3.6e-19 69.3 12.9 6.4e-19 68.5 12.9 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 OWF37507.1 - 5.3e-16 57.4 0.6 0.00012 21.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF37507.1 - 7.5e-15 54.0 1.9 6.4e-06 25.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OWF37507.1 - 2.7e-10 40.7 0.0 1.3e-07 32.2 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF37507.1 - 9.2e-10 38.1 0.2 0.00055 19.6 0.0 3.3 1 1 2 3 3 3 3 TPR repeat ANAPC3 PF12895.7 OWF37507.1 - 5.2e-08 33.0 0.5 1e-07 32.1 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OWF37507.1 - 6.7e-08 32.2 1.6 0.03 14.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF37507.1 - 1.1e-06 28.3 0.2 0.24 11.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF37507.1 - 3.4e-06 27.2 1.9 0.00019 21.6 0.6 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF37507.1 - 5.8e-06 26.7 0.0 0.0091 16.5 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF37507.1 - 0.00015 22.3 0.1 2.8 9.0 0.0 3.8 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF37507.1 - 0.00023 21.3 0.0 0.0069 16.5 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF37507.1 - 0.00075 19.7 0.1 0.0083 16.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 OWF37507.1 - 0.00088 19.4 0.1 0.0035 17.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_6 PF13174.6 OWF37507.1 - 0.026 15.2 1.3 24 5.9 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DNA_meth_N PF18284.1 OWF37507.1 - 0.24 11.3 3.7 1.5 8.8 0.0 3.6 4 1 1 5 5 5 0 DNA methylase N-terminal domain DHDPS PF00701.22 OWF37508.1 - 6.1e-39 133.5 0.0 6.9e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DNA_ligase_A_M PF01068.21 OWF37508.1 - 0.0088 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Bac_luciferase PF00296.20 OWF37508.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Luciferase-like monooxygenase PGP_phosphatase PF09419.10 OWF37508.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DHDPS PF00701.22 OWF37509.1 - 2e-41 141.6 0.0 2.3e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SfLAP PF11139.8 OWF37510.1 - 0.0011 18.5 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein PIRT PF15099.6 OWF37510.1 - 0.0011 18.5 0.2 0.0025 17.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM171 PF15471.6 OWF37510.1 - 0.003 16.6 6.3 0.2 10.6 0.0 2.5 2 1 1 3 3 3 3 Transmembrane protein family 171 DUF202 PF02656.15 OWF37510.1 - 0.0072 16.7 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TMEM174 PF15029.6 OWF37510.1 - 0.012 15.3 6.7 0.077 12.7 0.2 2.2 1 1 1 2 2 2 0 Transmembrane protein 174 Tetraspanin PF00335.20 OWF37510.1 - 0.014 15.1 0.7 0.025 14.3 0.7 1.3 1 0 0 1 1 1 0 Tetraspanin family SdpI PF13630.6 OWF37510.1 - 0.019 15.1 0.3 8.3 6.6 0.2 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF973 PF06157.11 OWF37510.1 - 0.026 13.6 0.6 0.033 13.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) TMEM100 PF16311.5 OWF37510.1 - 0.032 13.8 0.3 0.032 13.8 0.3 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 DUF3185 PF11381.8 OWF37510.1 - 0.063 13.3 1.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) TCR_zetazeta PF11628.8 OWF37510.1 - 0.076 12.7 1.4 0.14 11.9 1.4 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain DUF3040 PF11239.8 OWF37510.1 - 0.1 12.9 1.0 0.3 11.4 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) TMEM252 PF15664.5 OWF37510.1 - 0.15 11.8 2.9 0.42 10.3 1.0 2.2 1 1 1 2 2 2 0 Transmembrane protein 252 family Tmemb_55A PF09788.9 OWF37510.1 - 0.6 9.2 7.8 0.52 9.3 0.2 2.7 2 1 0 2 2 2 0 Transmembrane protein 55A TMEM52 PF14979.6 OWF37510.1 - 1.1 9.2 5.0 0.7 9.8 0.7 2.5 2 1 1 3 3 3 0 Transmembrane 52 UPF0728 PF15092.6 OWF37511.1 - 4.4e-08 32.8 0.0 4.8e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 UPF0728 PF15092.6 OWF37512.1 - 1.6e-09 37.4 0.1 1.8e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 DUF3238 PF11579.8 OWF37512.1 - 0.14 12.0 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) UPF0728 PF15092.6 OWF37513.1 - 7.1e-09 35.4 0.0 8.3e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 HORMA PF02301.18 OWF37514.1 - 3.5e-21 75.8 0.1 6e-21 75.0 0.1 1.3 1 1 0 1 1 1 1 HORMA domain ATG13 PF10033.9 OWF37514.1 - 0.014 15.1 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 bacHORMA_2 PF18173.1 OWF37514.1 - 0.026 14.4 0.3 0.049 13.5 0.3 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 Ala_racemase_N PF01168.20 OWF37514.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain FA_desaturase PF00487.24 OWF37515.1 - 2.2e-15 57.2 20.9 3.3e-15 56.6 20.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cu-oxidase_3 PF07732.15 OWF37516.1 - 2.8e-36 124.1 0.8 5.9e-35 119.9 0.4 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OWF37516.1 - 8e-29 100.8 0.2 4.2e-26 92.0 0.0 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF37516.1 - 0.00063 19.5 0.6 0.18 11.5 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase S4 PF01479.25 OWF37517.1 - 1.5e-11 43.8 1.8 4.2e-11 42.4 1.8 1.8 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OWF37517.1 - 7.7e-06 26.7 2.3 1.4e-05 25.9 2.3 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 OWF37517.1 - 0.075 13.2 0.4 4.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Flavin_Reduct PF01613.18 OWF37518.1 - 1.9e-35 122.2 0.2 2.6e-35 121.7 0.2 1.2 1 0 0 1 1 1 1 Flavin reductase like domain FtsJ PF01728.19 OWF37519.1 - 1.3e-53 181.7 0.0 1.6e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 OWF37519.1 - 0.0015 16.6 0.0 0.0022 16.1 0.0 1.1 1 0 0 1 1 1 1 Virus-capping methyltransferase Ribosomal_S10 PF00338.22 OWF37519.1 - 0.096 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e BK_channel_a PF03493.18 OWF37520.1 - 1.1e-37 128.2 0.0 2.8e-37 126.8 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 OWF37520.1 - 8.9e-21 74.2 13.7 2.1e-20 73.0 13.7 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF37520.1 - 8.3e-16 57.7 3.6 8.3e-16 57.7 3.6 2.7 4 0 0 4 4 4 1 Ion channel TrkA_N PF02254.18 OWF37520.1 - 0.0018 18.5 0.1 0.036 14.3 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.26 OWF37520.1 - 0.005 16.7 1.2 0.0082 16.0 0.1 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel DUF5413 PF17434.2 OWF37520.1 - 0.29 11.5 1.8 26 5.2 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5413) DUF2345 PF10106.9 OWF37521.1 - 1.2e-06 28.4 0.1 0.023 14.6 0.0 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) Sarcoglycan_1 PF04790.13 OWF37521.1 - 3.3e-05 23.4 0.0 0.012 14.9 0.0 2.7 1 1 2 3 3 3 3 Sarcoglycan complex subunit protein DUF1082 PF06449.11 OWF37521.1 - 0.00014 21.6 11.9 20 5.1 0.1 6.7 1 1 6 7 7 7 1 Mitochondrial domain of unknown function (DUF1082) Membrane_bind PF14564.6 OWF37521.1 - 0.00055 20.3 3.6 0.36 11.3 1.2 3.7 1 1 3 4 4 4 2 Membrane binding DUF2944 PF11161.8 OWF37521.1 - 0.014 15.2 0.5 2.1 8.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) DUF4720 PF15846.5 OWF37521.1 - 0.09 12.6 0.7 1.2 9.0 0.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4720) Trypsin PF00089.26 OWF37522.1 - 7.2e-68 228.7 0.9 1.1e-67 228.1 0.9 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF37522.1 - 1.6e-08 35.6 0.0 3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF37522.1 - 0.029 14.7 0.1 0.059 13.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) 7tm_1 PF00001.21 OWF37523.1 - 5e-15 55.5 12.6 6.6e-15 55.1 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF37523.1 - 6.7e-07 28.9 16.4 4.3e-06 26.2 16.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF37523.1 - 1.7e-06 27.6 14.1 1.7e-05 24.3 14.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF37523.1 - 0.048 13.3 15.2 0.17 11.5 15.2 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx RhoGAP PF00620.27 OWF37524.1 - 1e-33 116.3 0.0 2.4e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RA PF00788.23 OWF37524.1 - 4.3e-07 30.5 0.2 1e-06 29.3 0.2 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Fer2 PF00111.27 OWF37525.1 - 1.3e-07 31.4 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cu_amine_oxid PF01179.20 OWF37526.1 - 2.1e-100 336.6 0.7 2.6e-100 336.2 0.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OWF37526.1 - 4.6e-06 26.8 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain YyzF PF14116.6 OWF37526.1 - 0.055 13.5 0.6 0.13 12.4 0.6 1.5 1 0 0 1 1 1 0 YyzF-like protein Radial_spoke_3 PF06098.11 OWF37527.1 - 1.6e-132 441.1 14.2 2.2e-132 440.6 14.2 1.2 1 0 0 1 1 1 1 Radial spoke protein 3 DUF2009 PF09418.10 OWF37527.1 - 0.091 11.8 0.8 0.13 11.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) LprI PF07007.12 OWF37527.1 - 0.14 12.8 4.3 0.7 10.6 4.3 2.2 1 1 0 1 1 1 0 Lysozyme inhibitor LprI Stm1_N PF09598.10 OWF37527.1 - 4.4 8.2 12.7 0.15 12.9 4.6 2.6 2 0 0 2 2 2 0 Stm1 CD24 PF14984.6 OWF37527.1 - 4.4 7.6 4.2 5.4 7.3 3.4 1.5 1 1 0 1 1 1 0 CD24 protein 5_nucleotid PF05761.14 OWF37527.1 - 6.1 5.6 6.7 20 3.9 3.7 2.1 2 0 0 2 2 2 0 5' nucleotidase family zf-C2H2 PF00096.26 OWF37528.1 - 1.5e-17 63.0 21.4 3.6e-05 24.0 0.9 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF37528.1 - 2.6e-13 49.8 15.4 1.1e-05 25.6 0.2 5.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF37528.1 - 1.2e-10 41.3 29.0 0.0027 18.4 0.5 5.8 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF37528.1 - 1.1e-07 31.9 3.2 0.24 11.7 0.4 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 OWF37528.1 - 1.2e-06 28.4 16.0 0.0023 17.9 0.4 3.7 3 0 0 3 3 3 2 BED zinc finger GAGA PF09237.11 OWF37528.1 - 0.0055 16.5 0.6 0.013 15.2 0.6 1.7 1 0 0 1 1 1 1 GAGA factor zf-C2H2_6 PF13912.6 OWF37528.1 - 0.018 15.0 15.0 0.25 11.4 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 OWF37528.1 - 0.05 14.0 9.3 2.9 8.4 0.0 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 OWF37528.1 - 0.1 12.2 3.9 46 3.7 0.0 4.1 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2HE PF16278.5 OWF37528.1 - 0.24 11.9 9.8 8.6 6.9 0.2 4.3 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 OWF37528.1 - 0.25 11.3 10.2 0.44 10.5 0.1 3.9 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-ribbon_3 PF13248.6 OWF37528.1 - 1 8.9 4.6 2.5 7.6 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_5 PF13909.6 OWF37528.1 - 3.1 7.6 17.0 9.3 6.1 3.7 4.6 4 1 0 4 4 3 0 C2H2-type zinc-finger domain TF_Zn_Ribbon PF08271.12 OWF37528.1 - 3.4 7.3 5.8 5.9 6.5 0.3 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_15 PF17032.5 OWF37528.1 - 3.9 8.3 7.7 17 6.2 2.1 3.6 3 1 0 3 3 2 0 zinc-ribbon family ADK_lid PF05191.14 OWF37528.1 - 4 7.5 16.4 23 5.1 0.4 3.9 3 1 1 4 4 4 0 Adenylate kinase, active site lid Arc_trans_TRASH PF08394.10 OWF37528.1 - 4.5 7.7 9.5 0.65 10.4 0.1 3.6 3 1 0 3 3 3 0 Archaeal TRASH domain Sec2p PF06428.11 OWF37529.1 - 8e-07 28.9 10.8 8e-07 28.9 10.8 2.8 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Csm2_III-A PF03750.13 OWF37529.1 - 0.28 12.0 6.5 10 7.0 1.2 3.2 2 1 1 3 3 3 0 Csm2 Type III-A FapA PF03961.13 OWF37529.1 - 4.8 5.7 6.9 6.9 5.2 6.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A GMC_oxred_N PF00732.19 OWF37530.1 - 1.7e-70 237.8 0.0 2.2e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF37530.1 - 5.1e-35 121.1 0.0 8.6e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OWF37530.1 - 4.4e-05 23.2 0.1 0.00017 21.3 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF37530.1 - 0.00014 22.1 0.3 0.00038 20.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OWF37530.1 - 0.00033 19.8 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OWF37530.1 - 0.0074 15.5 0.0 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TPPK_C PF12555.8 OWF37530.1 - 0.0077 16.3 0.7 0.028 14.5 0.7 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal FAD_binding_2 PF00890.24 OWF37530.1 - 0.012 14.7 0.2 0.32 10.0 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 OWF37530.1 - 0.016 14.4 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Voltage_CLC PF00654.20 OWF37530.1 - 0.076 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel Tail_VII PF17091.5 OWF37530.1 - 1.3 9.0 3.1 3.3 7.7 3.1 1.7 1 0 0 1 1 1 0 Inovirus G7P protein Ion_trans PF00520.31 OWF37531.1 - 3.3e-29 101.8 20.0 3.3e-29 101.8 20.0 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 OWF37531.1 - 7.5e-12 45.0 8.2 7.5e-12 45.0 8.2 2.5 2 0 0 2 2 2 1 Ion channel BTB_2 PF02214.22 OWF37531.1 - 9.5e-07 29.1 0.1 3.4e-06 27.3 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain CytadhesinP1 PF12378.8 OWF37531.1 - 0.081 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein TauD PF02668.16 OWF37532.1 - 2.3e-29 103.0 0.0 3.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OWF37532.1 - 1.2e-13 51.4 0.2 6.9e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 OWF37532.1 - 0.0032 16.6 0.0 0.0051 16.0 0.0 1.4 1 0 0 1 1 1 1 CsiD PLAC8 PF04749.17 OWF37533.1 - 3.2e-13 50.5 16.4 4e-13 50.2 16.4 1.1 1 0 0 1 1 1 1 PLAC8 family M20_dimer PF07687.14 OWF37534.1 - 2.3e-10 40.3 0.0 4.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OWF37534.1 - 7.7e-10 38.8 0.1 1e-09 38.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 S-methyl_trans PF02574.16 OWF37535.1 - 3.7e-39 135.1 0.0 4.6e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase eIF-1a PF01176.19 OWF37536.1 - 3.4e-21 74.8 0.0 4.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-C4H2 PF10146.9 OWF37537.1 - 6.1e-78 262.0 16.7 7e-78 261.8 16.7 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein ETC_C1_NDUFA5 PF04716.14 OWF37537.1 - 0.0074 16.1 0.8 0.019 14.8 0.8 1.7 1 0 0 1 1 1 1 ETC complex I subunit conserved region DZR PF12773.7 OWF37537.1 - 0.0091 16.0 1.0 0.015 15.3 1.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_3 PF13920.6 OWF37537.1 - 0.075 12.9 4.2 0.12 12.3 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 OWF37537.1 - 0.1 12.3 2.2 0.17 11.5 2.2 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 OWF37537.1 - 0.11 12.4 2.7 0.24 11.2 2.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EspB_PE PF18625.1 OWF37537.1 - 0.25 11.8 6.0 1.4 9.4 0.5 3.2 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain DUF3365 PF11845.8 OWF37537.1 - 0.35 11.2 5.1 0.33 11.2 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) LTXXQ PF07813.12 OWF37537.1 - 0.45 11.3 11.8 0.12 13.1 3.0 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein DUF4404 PF14357.6 OWF37537.1 - 1 10.1 9.3 4.2 8.1 7.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Exonuc_VII_L PF02601.15 OWF37537.1 - 1.6 8.2 5.9 2 7.9 5.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 OWF37537.1 - 1.9 8.7 17.0 0.98 9.7 13.5 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 OWF37537.1 - 6.6 7.4 8.7 3.4 8.4 0.4 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CAP PF00188.26 OWF37538.1 - 3.2e-21 76.5 3.7 3.2e-21 76.5 3.7 2.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family PDR_CDR PF06422.12 OWF37538.1 - 0.042 13.7 0.9 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 CDR ABC transporter Peptidase_M24_C PF16188.5 OWF37538.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 Glyco_hydro_99 PF16317.5 OWF37539.1 - 4e-146 486.5 10.8 4.9e-146 486.3 10.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 OWF37539.1 - 0.0022 17.5 0.5 0.0022 17.5 0.5 1.9 2 1 0 2 2 2 1 Glycosyltransferase WbsX SKA1 PF07160.12 OWF37539.1 - 0.29 11.0 3.5 0.45 10.3 3.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CTD_bind PF04818.13 OWF37540.1 - 1.3e-16 61.2 1.0 2.6e-16 60.2 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 OWF37540.1 - 2e-10 40.3 0.0 3.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF37540.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sod_Cu PF00080.20 OWF37541.1 - 2e-46 157.7 5.6 2.5e-46 157.4 5.6 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) UBA_6 PF18039.1 OWF37542.1 - 2.2e-17 62.7 0.2 4.1e-17 61.8 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain RNase_Zc3h12a PF11977.8 OWF37542.1 - 0.073 12.9 0.2 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain RNase_Zc3h12a PF11977.8 OWF37543.1 - 4e-56 189.1 0.0 8.3e-56 188.1 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Regnase_1_C PF18561.1 OWF37543.1 - 6e-12 45.1 0.0 1.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain zf-CCCH_4 PF18044.1 OWF37543.1 - 0.00032 20.4 4.7 0.00072 19.3 4.7 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OWF37543.1 - 0.016 15.1 4.4 0.028 14.3 3.1 2.0 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OWF37543.1 - 2.5 8.7 6.9 4.8 7.8 6.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 OWF37543.1 - 2.8 8.1 5.9 10 6.3 5.9 2.0 1 1 0 1 1 1 0 Zinc finger domain Las1 PF04031.13 OWF37544.1 - 1.9e-43 148.3 0.4 3.1e-43 147.5 0.4 1.4 1 0 0 1 1 1 1 Las1-like CSN5_C PF18323.1 OWF37544.1 - 0.34 11.8 2.7 0.49 11.3 1.0 2.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain LPMO_10 PF03067.15 OWF37545.1 - 0.00045 20.9 0.1 0.00067 20.4 0.1 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading NPV_P10 PF05531.12 OWF37546.1 - 0.0029 18.0 2.4 3.9 8.0 0.0 2.9 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein PriC PF07445.12 OWF37546.1 - 0.0051 16.7 0.1 0.0051 16.7 0.1 1.6 2 0 0 2 2 2 1 Primosomal replication protein priC Phage_holin_3_6 PF07332.11 OWF37546.1 - 0.048 13.7 3.0 0.47 10.5 0.1 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HalX PF08663.10 OWF37546.1 - 0.64 10.4 0.1 0.64 10.4 0.1 2.2 3 0 0 3 3 3 0 HalX domain DUF716 PF04819.12 OWF37547.1 - 1.7e-25 89.2 5.0 3.9e-25 88.1 5.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF716) Amidase PF01425.21 OWF37548.1 - 7.3e-125 417.4 0.0 1.1e-87 294.9 0.0 2.0 2 0 0 2 2 2 2 Amidase TAL_FSA PF00923.19 OWF37549.1 - 1.8e-98 329.5 2.7 2e-98 329.3 2.7 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FAD_binding_7 PF03441.14 OWF37550.1 - 1.6e-68 230.2 1.1 2.5e-68 229.6 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OWF37550.1 - 1.3e-42 145.5 0.0 2.1e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase SDA1 PF05285.12 OWF37551.1 - 7.9 5.8 26.4 8.9 5.6 26.4 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OWF37551.1 - 8.9 4.4 27.1 9.9 4.2 27.1 1.1 1 0 0 1 1 1 0 Nop14-like family ADH_N_2 PF16884.5 OWF37552.1 - 2.3e-26 91.8 0.0 3.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OWF37552.1 - 6.4e-23 81.2 0.1 9.7e-23 80.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF37552.1 - 7.1e-11 43.3 0.0 1.6e-10 42.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase EIIA-man PF03610.16 OWF37552.1 - 0.028 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component NifU_N PF01592.16 OWF37552.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 NifU-like N terminal domain NDUF_B8 PF05821.11 OWF37553.1 - 4.8e-15 55.9 3.2 6e-15 55.5 3.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Folliculin PF11704.8 OWF37554.1 - 2.6e-06 27.4 0.3 8.1e-06 25.8 0.3 1.8 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport IFT57 PF10498.9 OWF37554.1 - 0.057 12.4 2.3 0.12 11.4 2.3 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Phage_Nu1 PF07471.12 OWF37554.1 - 0.17 11.6 0.2 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 DUF4471 PF14740.6 OWF37555.1 - 0.027 13.7 1.3 0.06 12.6 1.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) zf-trcl PF13451.6 OWF37555.1 - 0.48 10.4 7.8 0.16 11.9 2.6 2.6 2 0 0 2 2 2 0 Probable zinc-ribbon domain Sugar_tr PF00083.24 OWF37556.1 - 1.6e-32 113.0 18.3 2.3e-32 112.5 18.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37556.1 - 7.5e-23 81.0 24.0 2.6e-11 43.1 6.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37557.1 - 4.9e-34 118.0 16.0 6.8e-34 117.5 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37557.1 - 8.3e-29 100.6 26.4 5.5e-20 71.6 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37558.1 - 3.7e-37 128.3 21.6 1.1e-36 126.8 21.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37558.1 - 3.2e-22 78.9 38.8 1e-15 57.5 18.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily LPAM_1 PF08139.12 OWF37558.1 - 0.25 11.9 2.8 5.3 7.7 0.4 3.5 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Sugar_tr PF00083.24 OWF37559.1 - 1.8e-35 122.7 14.7 2.4e-35 122.3 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37559.1 - 1e-28 100.3 33.5 6.5e-16 58.2 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF37559.1 - 0.0014 18.0 3.4 0.0014 18.0 3.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OWF37560.1 - 8.6e-39 133.6 13.7 1.4e-38 132.9 13.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37560.1 - 3.2e-30 105.2 34.9 3e-22 79.0 13.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF37560.1 - 3.5e-05 23.3 2.9 3.5e-05 23.3 2.9 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pkr1 PF08636.10 OWF37560.1 - 0.04 14.1 0.5 14 5.9 0.0 3.1 2 0 0 2 2 2 0 ER protein Pkr1 Sugar_tr PF00083.24 OWF37561.1 - 2.2e-32 112.5 12.4 2.2e-32 112.5 12.4 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37561.1 - 6.9e-24 84.4 33.2 2.1e-15 56.5 15.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37562.1 - 2.6e-38 132.1 14.8 3.4e-38 131.7 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37562.1 - 1.2e-22 80.3 32.4 2.9e-15 56.1 9.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM47 PF14642.6 OWF37563.1 - 3.2e-05 23.6 12.4 0.98 8.9 0.5 5.7 1 1 5 7 7 7 4 FAM47 family GDC-P PF02347.16 OWF37563.1 - 0.15 10.8 1.8 7.7 5.2 0.1 3.0 2 2 1 3 3 3 0 Glycine cleavage system P-protein CARD PF00619.21 OWF37564.1 - 8.7e-09 35.3 0.1 2.3e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 Caspase recruitment domain TPR_2 PF07719.17 OWF37564.1 - 2.5 8.4 4.9 2.4 8.5 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ALS2CR8 PF15299.6 OWF37566.1 - 9e-46 156.5 0.1 1.5e-45 155.8 0.1 1.3 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Sushi PF00084.20 OWF37567.1 - 4.4e-09 36.8 2.0 9.4e-09 35.7 2.0 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) TMEM52 PF14979.6 OWF37567.1 - 0.0031 17.4 0.3 0.0031 17.4 0.3 1.6 2 0 0 2 2 2 1 Transmembrane 52 Prominin PF05478.11 OWF37567.1 - 0.0049 14.9 2.6 0.0064 14.5 2.6 1.1 1 0 0 1 1 1 1 Prominin ECSCR PF15820.5 OWF37567.1 - 0.059 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Corona_S2 PF01601.16 OWF37567.1 - 1.3 7.4 3.4 2 6.8 3.4 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CRIC_ras_sig PF10534.9 OWF37568.1 - 4.6e-19 68.4 0.2 2.1e-18 66.2 0.2 2.3 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras PH PF00169.29 OWF37568.1 - 3.4e-13 50.0 0.5 1.2e-12 48.3 0.5 1.9 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 OWF37568.1 - 8.6e-12 45.3 0.3 2.2e-11 44.0 0.1 1.9 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 OWF37568.1 - 1.7e-10 40.5 0.1 6.1e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OWF37568.1 - 3.6e-09 36.9 0.3 2.4e-08 34.2 0.2 2.5 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 OWF37568.1 - 2.5e-07 30.7 0.3 8.3e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 OWF37568.1 - 9.7e-05 22.7 3.1 0.00059 20.2 3.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PDZ_2 PF13180.6 OWF37568.1 - 0.023 15.0 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PH_3 PF14593.6 OWF37568.1 - 0.053 13.6 0.1 0.21 11.7 0.1 2.0 1 0 0 1 1 1 0 PH domain SAM_PNT PF02198.16 OWF37568.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fn_bind PF02986.14 OWF37568.1 - 0.8 9.5 11.1 1.5 8.6 5.6 2.8 2 0 0 2 2 2 0 Fibronectin binding repeat Sulfatase PF00884.23 OWF37569.1 - 4.6e-80 269.3 0.0 6.6e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OWF37569.1 - 2.2e-30 105.9 0.0 1.1e-29 103.7 0.1 1.9 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OWF37569.1 - 5e-08 32.9 0.0 0.0027 17.4 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Bys1 PF04681.12 OWF37569.1 - 0.0028 17.6 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein DUF1722 PF08349.11 OWF37570.1 - 4.8e-07 30.1 36.7 2.6 8.3 1.1 6.7 1 1 7 8 8 8 8 Protein of unknown function (DUF1722) PMBR PF09373.10 OWF37570.1 - 2e-05 24.5 23.5 3.6e+02 1.6 0.0 14.0 1 1 20 21 21 21 0 Pseudomurein-binding repeat Dak2 PF02734.17 OWF37570.1 - 3.7e-05 23.7 20.5 4.8 7.1 0.7 5.9 1 1 9 10 10 10 9 DAK2 domain Leg1 PF05612.12 OWF37570.1 - 0.2 10.8 42.0 7.4 5.6 3.6 5.5 1 1 5 6 6 6 0 Leg1 MIEAP PF16026.5 OWF37570.1 - 1.3 9.2 44.7 23 5.1 3.1 5.6 1 1 3 4 4 4 0 Mitochondria-eating protein ACC_central PF08326.12 OWF37571.1 - 1.9e-248 826.5 9.4 2.7e-248 826.0 9.4 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OWF37571.1 - 6.1e-176 585.9 0.0 8.2e-176 585.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OWF37571.1 - 1.6e-53 181.3 0.8 4.6e-53 179.9 0.1 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OWF37571.1 - 2.9e-33 114.7 0.0 5.9e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OWF37571.1 - 9.2e-21 74.0 0.0 4.2e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OWF37571.1 - 3.1e-14 52.6 0.1 1.1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 OWF37571.1 - 0.0058 16.2 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OWF37571.1 - 0.024 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OWF37571.1 - 0.047 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain TIG PF01833.24 OWF37571.1 - 0.095 12.8 0.1 10 6.3 0.0 3.4 3 0 0 3 3 3 0 IPT/TIG domain DHC_N1 PF08385.12 OWF37572.1 - 4.2e-118 395.4 3.7 1.9e-78 264.5 3.8 6.2 7 1 0 7 7 7 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OWF37572.1 - 3.9e-92 309.4 5.6 7.9e-92 308.4 3.9 6.6 8 0 0 8 8 7 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OWF37572.1 - 7.5e-66 222.3 0.0 8.7e-53 179.4 0.0 3.1 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OWF37572.1 - 9.1e-55 186.0 0.6 3.4e-54 184.2 0.0 2.4 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 OWF37572.1 - 1.5e-44 151.7 1.4 4.8e-39 133.7 0.0 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_8 PF12780.7 OWF37572.1 - 4.5e-42 144.2 0.6 2e-39 135.5 0.0 3.3 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF37572.1 - 1.3e-31 109.5 3.2 3.4e-31 108.1 1.6 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OWF37572.1 - 9.2e-25 87.4 0.0 5.6e-24 84.8 0.0 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OWF37572.1 - 1.6e-21 76.6 1.6 1.2e-19 70.6 0.4 4.0 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF37572.1 - 4.5e-17 62.3 0.3 1.2e-14 54.5 0.0 3.8 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF37572.1 - 6.9e-12 45.5 0.0 0.0017 18.3 0.0 4.8 4 0 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA PF00004.29 OWF37572.1 - 2.3e-11 44.3 0.2 0.034 14.6 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF37572.1 - 6.7e-09 36.1 2.4 0.2 11.9 0.0 5.5 6 0 0 6 6 4 2 AAA domain AAA_16 PF13191.6 OWF37572.1 - 1.1e-07 32.5 7.6 0.0066 16.9 0.0 5.4 6 0 0 6 6 3 2 AAA ATPase domain AAA_lid_1 PF17857.1 OWF37572.1 - 9.8e-07 28.9 0.0 5.6e-06 26.5 0.0 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 OWF37572.1 - 1.6e-06 28.7 0.6 0.16 12.5 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 OWF37572.1 - 4.3e-06 26.4 1.4 0.15 11.8 0.0 4.1 4 0 0 4 4 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OWF37572.1 - 6e-06 25.8 0.1 0.0056 16.1 0.0 2.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Mg_chelatase PF01078.21 OWF37572.1 - 6e-05 22.5 0.0 0.025 13.9 0.0 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OWF37572.1 - 8e-05 23.0 0.6 0.58 10.6 0.0 4.6 4 0 0 4 4 3 1 RNA helicase AAA_33 PF13671.6 OWF37572.1 - 0.00046 20.4 1.4 1.4 9.1 0.1 3.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OWF37572.1 - 0.00046 20.0 3.6 5.7 6.6 0.0 4.6 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 OWF37572.1 - 0.00051 20.1 0.2 3.8 7.5 0.0 4.1 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OWF37572.1 - 0.00092 19.2 1.1 0.66 9.9 0.0 3.7 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 OWF37572.1 - 0.0013 18.7 4.6 1 9.3 0.0 4.2 4 0 0 4 4 4 1 NACHT domain ABC_tran PF00005.27 OWF37572.1 - 0.002 18.6 6.7 0.12 12.8 0.0 4.1 4 0 0 4 4 2 1 ABC transporter AAA_30 PF13604.6 OWF37572.1 - 0.0023 17.7 0.1 3.1 7.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 OWF37572.1 - 0.0023 17.7 2.1 0.072 12.8 0.1 3.4 4 0 0 4 4 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 OWF37572.1 - 0.0036 17.2 1.2 0.49 10.3 0.1 3.6 3 0 0 3 3 3 1 NTPase Septin PF00735.18 OWF37572.1 - 0.0036 16.6 0.1 1.6 7.9 0.0 3.2 3 0 0 3 3 3 1 Septin AAA_28 PF13521.6 OWF37572.1 - 0.0039 17.4 1.0 15 5.8 0.0 4.2 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 OWF37572.1 - 0.01 16.0 0.2 6.8 6.8 0.0 3.4 3 0 0 3 3 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 OWF37572.1 - 0.011 15.0 0.1 3.2 7.0 0.0 3.1 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 OWF37572.1 - 0.012 15.7 0.8 3.1 7.9 0.1 3.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Rad17 PF03215.15 OWF37572.1 - 0.012 15.5 0.4 1.6 8.6 0.0 3.2 2 0 0 2 2 2 0 Rad17 P-loop domain Roc PF08477.13 OWF37572.1 - 0.014 15.6 0.1 0.21 11.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 OWF37572.1 - 0.016 14.3 0.0 0.81 8.7 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 OWF37572.1 - 0.02 14.7 1.6 1.8 8.3 0.2 3.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 OWF37572.1 - 0.02 15.2 6.2 1.4 9.3 0.0 4.5 5 0 0 5 5 3 0 AAA domain cobW PF02492.19 OWF37572.1 - 0.021 14.4 1.0 16 5.1 0.0 3.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 OWF37572.1 - 0.049 13.4 0.3 0.35 10.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF37572.1 - 0.21 11.0 1.6 3.3 7.1 0.0 2.9 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain dNK PF01712.19 OWF37572.1 - 1.7 8.5 7.6 4 7.2 0.0 4.7 4 0 0 4 4 3 0 Deoxynucleoside kinase NPV_P10 PF05531.12 OWF37572.1 - 2.1 8.8 15.7 28 5.3 0.3 6.3 5 0 0 5 5 4 0 Nucleopolyhedrovirus P10 protein PB1 PF00564.24 OWF37574.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Translin PF01997.16 OWF37574.1 - 0.0074 16.3 1.5 0.02 14.9 0.8 1.8 1 1 1 2 2 2 1 Translin family Focal_AT PF03623.13 OWF37574.1 - 0.012 15.7 3.4 0.021 14.8 1.4 2.0 1 1 1 2 2 2 0 Focal adhesion targeting region DUF1730 PF08331.10 OWF37574.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Fzo_mitofusin PF04799.13 OWF37574.1 - 0.078 12.5 0.9 0.12 11.9 0.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF4446 PF14584.6 OWF37574.1 - 0.14 12.2 1.6 0.24 11.4 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Uds1 PF15456.6 OWF37574.1 - 0.17 12.0 2.9 0.87 9.7 0.8 2.3 1 1 1 2 2 2 0 Up-regulated During Septation DASH_Dad3 PF08656.10 OWF37574.1 - 0.48 10.5 3.6 1.4 9.1 3.6 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 TSC22 PF01166.18 OWF37574.1 - 0.55 10.6 5.0 0.51 10.7 2.7 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Ribosom_S12_S23 PF00164.25 OWF37575.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S12/S23 SHIPPO-rpt PF07004.12 OWF37576.1 - 3.1e-11 43.6 45.7 0.00022 22.0 5.4 6.1 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat SHIPPO-rpt PF07004.12 OWF37577.1 - 1.3e-15 57.5 33.0 8.6e-06 26.4 0.5 6.7 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat ATP-gua_Ptrans PF00217.19 OWF37578.1 - 4.8e-77 258.2 0.0 7.1e-77 257.6 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 OWF37578.1 - 6.6e-23 80.9 0.0 1.2e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.19 OWF37579.1 - 1.4e-158 524.7 0.0 1.4e-78 263.2 0.0 2.2 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 OWF37579.1 - 3.6e-52 174.6 0.1 1.7e-25 89.2 0.0 2.6 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain Sulf_transp PF04143.14 OWF37580.1 - 4.6e-20 72.4 6.6 7e-20 71.8 6.6 1.2 1 0 0 1 1 1 1 Sulphur transport Rick_17kDa_Anti PF05433.15 OWF37580.1 - 0.38 10.6 6.1 1.2 9.0 6.1 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain Phage_HK97_TLTM PF06120.11 OWF37580.1 - 0.59 9.3 4.6 1.1 8.4 4.6 1.3 1 0 0 1 1 1 0 Tail length tape measure protein Asparaginase_2 PF01112.18 OWF37581.1 - 3.2e-60 203.8 3.9 5.4e-60 203.0 3.9 1.4 1 1 0 1 1 1 1 Asparaginase Sec23_trunk PF04811.15 OWF37582.1 - 1.5e-76 257.1 0.0 2.4e-76 256.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OWF37582.1 - 2.9e-33 114.5 0.0 7.1e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OWF37582.1 - 1.4e-27 95.5 0.1 3.9e-27 94.1 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OWF37582.1 - 8.4e-16 57.7 9.2 1.7e-15 56.7 9.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OWF37582.1 - 2.3e-13 49.8 0.1 6.6e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Gelsolin repeat Mannosyl_trans3 PF11051.8 OWF37582.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative EF-hand_7 PF13499.6 OWF37583.1 - 1.1e-17 64.2 5.7 1.1e-13 51.4 1.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF37583.1 - 4.8e-17 60.2 7.7 2.8e-06 26.5 0.6 4.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OWF37583.1 - 5.2e-15 54.0 3.3 1.7e-06 27.5 0.3 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 OWF37583.1 - 3.1e-09 35.9 7.3 0.00073 18.9 0.2 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OWF37583.1 - 4.9e-06 26.3 6.0 0.00014 21.6 0.9 3.9 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF37583.1 - 1.4e-05 25.3 0.3 0.0011 19.3 0.4 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF37583.1 - 0.017 15.1 1.5 0.41 10.6 0.5 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OWF37583.1 - 0.043 14.0 5.6 3.8 7.8 2.6 3.6 3 1 1 4 4 4 0 Dockerin type I domain DIMCO_N PF16844.5 OWF37583.1 - 0.057 13.7 0.1 0.26 11.6 0.0 1.9 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal RST PF12174.8 OWF37583.1 - 0.068 13.1 0.3 0.38 10.7 0.0 2.4 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain CIA30 PF08547.12 OWF37584.1 - 4.5e-22 78.8 0.1 1.2e-21 77.4 0.1 1.8 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Fascin PF06268.13 OWF37584.1 - 0.084 13.1 0.2 0.92 9.8 0.2 2.6 1 1 1 2 2 2 0 Fascin domain YTV PF07639.11 OWF37584.1 - 0.12 12.5 1.7 0.76 9.9 0.1 2.8 3 0 0 3 3 3 0 YTV Acetyltransf_1 PF00583.25 OWF37585.1 - 7.9e-09 35.8 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF37585.1 - 5e-07 30.1 0.0 7.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF37585.1 - 9.2e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDP-OH_P_transf PF01066.21 OWF37586.1 - 1.1e-10 42.1 0.3 1.1e-10 42.1 0.3 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DDHD PF02862.17 OWF37587.1 - 1.7e-46 159.2 0.1 3.3e-46 158.2 0.1 1.5 1 0 0 1 1 1 1 DDHD domain DUF3911 PF13050.6 OWF37587.1 - 0.14 12.2 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) DUF4391 PF14335.6 OWF37587.1 - 0.29 10.8 1.7 9.7 5.8 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4391) UPF0767 PF15990.5 OWF37588.1 - 6.4e-23 80.7 0.0 7.4e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 UPF0767 family Secretogranin_V PF05281.11 OWF37589.1 - 8.5e-38 130.2 0.8 1e-37 130.0 0.8 1.2 1 0 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) AMPK1_CBM PF16561.5 OWF37590.1 - 3.6e-15 56.0 0.1 7e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 OWF37590.1 - 0.01 16.4 0.1 0.025 15.2 0.1 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) TcpA PF05946.12 OWF37591.1 - 0.13 12.4 11.1 0.89 9.7 0.8 3.8 1 1 3 4 4 4 0 Toxin-coregulated pilus subunit TcpA GPI PF06560.11 OWF37591.1 - 0.16 11.2 1.7 3.7 6.8 0.1 2.7 1 1 3 4 4 4 0 Glucose-6-phosphate isomerase (GPI) DNA_alkylation PF08713.11 OWF37592.1 - 8.3e-61 205.4 1.9 1e-60 205.1 1.9 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme Ccdc124 PF06244.12 OWF37592.1 - 0.1 13.1 0.1 0.23 12.0 0.1 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Clathrin_bdg PF15045.6 OWF37593.1 - 5.4e-08 32.7 0.2 2.6e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Hormone_recep PF00104.30 OWF37594.1 - 8.4e-32 110.4 1.4 1.4e-31 109.7 1.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF37594.1 - 3.1e-31 107.6 12.4 3.1e-31 107.6 12.4 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Rdx PF10262.9 OWF37595.1 - 7e-07 29.4 0.0 8.4e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Rdx family DsbC_N PF10411.9 OWF37595.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.6 1 1 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Kelch_4 PF13418.6 OWF37596.1 - 2.6e-39 133.0 2.5 2e-07 30.9 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF37596.1 - 5.3e-37 125.4 3.8 7.5e-08 32.5 0.0 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF37596.1 - 8.4e-31 105.5 2.2 2.2e-05 24.3 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 OWF37596.1 - 1.2e-22 79.3 7.2 0.001 18.6 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OWF37596.1 - 3.8e-21 74.6 11.7 0.00074 19.7 0.1 6.7 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OWF37596.1 - 6.9e-18 63.9 12.7 0.00035 20.4 0.3 6.4 6 0 0 6 6 6 5 Kelch motif FCP1_C PF09309.10 OWF37596.1 - 1.4 8.8 16.5 2.1 8.1 16.5 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Ion_trans_2 PF07885.16 OWF37598.1 - 5e-32 109.7 24.6 3.6e-16 58.9 8.1 3.2 3 0 0 3 3 3 2 Ion channel Phasin PF05597.11 OWF37598.1 - 0.007 16.4 0.5 0.014 15.4 0.5 1.4 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3810 PF12725.7 OWF37598.1 - 0.015 14.7 0.6 0.015 14.7 0.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3810) IRK PF01007.20 OWF37598.1 - 0.082 12.7 0.3 0.082 12.7 0.3 2.5 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain DUF2670 PF10875.8 OWF37598.1 - 0.19 11.8 1.5 0.78 9.8 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2670) MpPF26 PF07666.11 OWF37598.1 - 0.25 11.5 0.2 0.25 11.5 0.2 3.2 4 0 0 4 4 4 0 M penetrans paralogue family 26 Na_Ca_ex PF01699.24 OWF37598.1 - 1.2 9.1 11.9 0.21 11.6 6.1 2.4 2 1 0 3 3 3 0 Sodium/calcium exchanger protein Gal-bind_lectin PF00337.22 OWF37599.1 - 1.6e-122 403.2 0.0 1.2e-32 112.2 0.0 4.0 4 0 0 4 4 4 4 Galactoside-binding lectin Phage_tube PF04985.14 OWF37599.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage tail tube protein FII Gal-bind_lectin PF00337.22 OWF37600.1 - 6e-118 388.4 0.5 4.4e-30 103.9 0.1 4.0 4 0 0 4 4 4 4 Galactoside-binding lectin Galactosyl_T PF01762.21 OWF37601.1 - 6e-45 153.5 0.0 9.4e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Cornichon PF03311.14 OWF37602.1 - 2.1e-49 166.9 9.5 2.5e-49 166.6 9.5 1.0 1 0 0 1 1 1 1 Cornichon protein PSII PF00421.19 OWF37602.1 - 0.15 10.7 1.4 0.24 10.1 1.0 1.4 1 1 0 1 1 1 0 Photosystem II protein WD40 PF00400.32 OWF37603.1 - 3.1e-11 43.6 2.9 0.026 15.4 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF37603.1 - 0.00051 20.3 0.0 3.2 8.1 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OWF37603.1 - 0.11 10.5 0.0 0.9 7.5 0.0 1.9 1 1 0 2 2 2 0 IKI3 family RRP36 PF06102.12 OWF37604.1 - 5.2e-49 166.4 33.5 5.2e-49 166.4 33.5 3.3 2 1 1 3 3 3 1 rRNA biogenesis protein RRP36 Ribosomal_L11 PF00298.19 OWF37605.1 - 3.6e-24 85.1 0.1 7.1e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 OWF37605.1 - 2.4e-20 72.1 0.1 4.5e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Styelin PF17562.2 OWF37605.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Styelin DUF382 PF04037.13 OWF37606.1 - 2.1e-59 199.2 1.7 2.1e-59 199.2 1.7 5.0 5 1 0 5 5 5 1 Domain of unknown function (DUF382) PSP PF04046.16 OWF37606.1 - 1.7e-20 72.6 3.8 1.7e-20 72.6 3.8 4.2 4 0 0 4 4 4 1 PSP SAP PF02037.27 OWF37606.1 - 1.4e-08 34.2 3.6 3.3e-08 33.1 0.8 2.6 2 0 0 2 2 2 1 SAP domain TFIIA PF03153.13 OWF37606.1 - 0.0011 19.1 19.3 0.0011 19.1 19.3 4.2 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit MOSC PF03473.17 OWF37607.1 - 3.6e-27 95.0 0.0 5.5e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OWF37607.1 - 1.9e-26 92.3 0.0 2.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OWF37608.1 - 2.2e-26 92.4 0.0 3.3e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OWF37608.1 - 0.00021 21.1 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain zf-C2H2_2 PF12756.7 OWF37609.1 - 0.013 15.8 1.3 0.013 15.8 1.3 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 OWF37609.1 - 8.8 6.8 12.7 1.9 9.0 1.2 3.7 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Xpo1 PF08389.12 OWF37610.1 - 2.6e-26 92.5 2.1 2.6e-26 92.5 2.1 3.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OWF37610.1 - 4.5e-07 29.7 0.3 2.5e-06 27.3 0.3 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain MMS19_N PF14500.6 OWF37610.1 - 0.017 14.7 0.2 0.085 12.4 0.0 2.3 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 OWF37610.1 - 0.043 14.4 0.2 0.29 11.8 0.1 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Reg_prop PF07494.11 OWF37611.1 - 7.2e-06 25.6 0.8 2 8.9 0.1 5.4 5 0 0 5 5 5 2 Two component regulator propeller WD40 PF00400.32 OWF37611.1 - 1.1e-05 26.1 2.6 0.26 12.2 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat NHL PF01436.21 OWF37611.1 - 0.0071 16.3 0.0 7.1 6.9 0.0 4.3 4 0 0 4 4 4 1 NHL repeat SGL PF08450.12 OWF37611.1 - 0.085 12.4 0.0 8.8 5.8 0.0 2.4 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Beach PF02138.18 OWF37612.1 - 4.6e-43 147.6 0.1 1.1e-42 146.3 0.1 1.6 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 OWF37612.1 - 2.6e-16 59.7 10.6 7.5e-05 23.4 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.25 OWF37612.1 - 1.5e-05 24.5 0.1 0.00011 21.7 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain ANAPC4_WD40 PF12894.7 OWF37612.1 - 0.0015 18.8 0.4 1.2 9.5 0.0 4.1 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OWF37612.1 - 0.027 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain PolyA_pol PF01743.20 OWF37613.1 - 7.9e-32 110.3 1.6 1.4e-31 109.5 1.6 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OWF37613.1 - 3.5e-11 42.7 0.0 1.6e-10 40.6 0.0 2.1 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Lipase_GDSL_2 PF13472.6 OWF37614.1 - 0.00037 20.9 0.0 0.0005 20.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DltD PF04914.12 OWF37614.1 - 0.0016 17.9 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 DltD protein PTS_2-RNA PF01885.16 OWF37615.1 - 1.5e-64 217.3 0.0 2.8e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF4374 PF14298.6 OWF37615.1 - 0.061 12.1 1.0 0.1 11.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4374) DUF4706 PF15797.5 OWF37616.1 - 1.6e-26 92.9 0.7 1.6e-26 92.9 0.7 2.9 2 1 2 4 4 4 1 Domain of unknown function (DUF4706) Beach PF02138.18 OWF37617.1 - 2.3e-108 361.8 1.5 4.5e-108 360.8 1.5 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OWF37617.1 - 2.2e-15 56.5 0.0 7.3e-15 54.9 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OWF37617.1 - 2.3e-05 25.0 14.8 0.015 16.1 1.7 6.1 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF4800 PF16057.5 OWF37617.1 - 0.0036 16.6 4.9 0.0082 15.4 4.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF1296 PF06972.11 OWF37617.1 - 8 6.7 7.4 5.1 7.3 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) adh_short PF00106.25 OWF37618.1 - 5e-47 159.9 0.0 6.5e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF37618.1 - 1e-29 103.8 0.0 1.3e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF37618.1 - 6.6e-11 42.4 0.1 9.1e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF37618.1 - 0.026 14.0 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 OWF37618.1 - 0.034 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 OWF37618.1 - 0.042 13.2 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1757 PF08560.10 OWF37618.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1757) adh_short PF00106.25 OWF37619.1 - 8e-49 165.8 0.0 1e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF37619.1 - 3.6e-31 108.5 0.0 4.6e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF37619.1 - 2e-11 44.1 0.1 3e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF37619.1 - 0.0064 16.0 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OWF37619.1 - 0.0079 15.5 0.0 0.18 11.1 0.0 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 OWF37619.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.16 OWF37619.1 - 0.14 12.8 0.4 0.41 11.3 0.4 1.8 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Hyd_WA PF06462.12 OWF37620.1 - 1.3e-35 121.0 39.4 6e-09 35.8 1.5 10.4 10 1 0 10 10 10 7 Propeller WD40_like PF17005.5 OWF37620.1 - 0.028 13.7 0.6 0.21 10.9 0.6 2.2 1 1 0 1 1 1 0 WD40-like domain ANAPC4_WD40 PF12894.7 OWF37620.1 - 0.14 12.5 0.1 2.1 8.7 0.0 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Meleagrin PF08189.11 OWF37620.1 - 0.79 9.5 6.6 17 5.2 0.0 4.3 5 0 0 5 5 5 0 Meleagrin/Cygnin family Mito_carr PF00153.27 OWF37621.1 - 3.3e-54 180.8 2.0 8.9e-20 70.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CTD PF12815.7 OWF37623.1 - 2e-20 73.1 68.2 1.8e+04 -46.9 68.2 10.9 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF1772 PF08592.11 OWF37627.1 - 8e-13 48.9 0.0 1.1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1772 PF08592.11 OWF37628.1 - 3.6e-15 56.5 0.0 4.1e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) polyprenyl_synt PF00348.17 OWF37629.1 - 9.2e-23 80.6 0.0 1.4e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase MCD PF05292.11 OWF37630.1 - 8.7e-98 327.0 0.0 1.3e-97 326.4 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 OWF37630.1 - 6.3e-16 58.3 0.2 2.3e-15 56.5 0.1 2.1 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain Aa_trans PF01490.18 OWF37631.1 - 4.8e-57 193.5 24.4 4.8e-57 193.5 24.4 1.5 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein Ni_hydr_CYTB PF01292.20 OWF37631.1 - 0.26 10.9 9.3 1.6 8.3 4.8 2.6 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF373 PF04123.13 OWF37631.1 - 0.67 9.3 11.9 0.024 14.1 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Aa_trans PF01490.18 OWF37632.1 - 2.7e-55 187.7 23.4 2.7e-55 187.7 23.4 1.5 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein dCache_3 PF14827.6 OWF37632.1 - 0.15 11.7 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase NrsF PF06532.11 OWF37632.1 - 5.5 6.7 14.1 3.1 7.5 1.0 3.3 2 1 1 3 3 3 0 Negative regulator of sigma F Aa_trans PF01490.18 OWF37634.1 - 4.8e-11 42.0 0.4 5.3e-11 41.9 0.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OWF37634.1 - 0.00064 18.9 1.1 0.0008 18.6 1.1 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family GMC_oxred_N PF00732.19 OWF37635.1 - 1.9e-82 277.0 0.1 2.6e-82 276.6 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF37635.1 - 4.6e-40 137.5 0.0 8.1e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF37635.1 - 1.1e-07 31.3 0.0 0.0019 17.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OWF37635.1 - 0.00024 21.3 0.3 0.00082 19.5 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OWF37635.1 - 0.00082 18.7 0.0 0.0047 16.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF37635.1 - 0.0024 17.2 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF37635.1 - 0.0052 15.9 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OWF37635.1 - 0.0065 16.1 2.8 0.03 13.9 2.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OWF37635.1 - 0.11 11.2 0.3 0.2 10.3 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 OWF37635.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SPATA3 PF15662.5 OWF37636.1 - 0.66 10.6 12.3 0.97 10.0 12.3 1.3 1 1 0 1 1 1 0 Spermatogenesis-associated protein 3 family Pro-rich PF15240.6 OWF37636.1 - 0.73 10.1 29.0 1.2 9.4 29.0 1.4 1 0 0 1 1 1 0 Proline-rich 7tm_1 PF00001.21 OWF37637.1 - 3.4e-49 167.5 17.5 4.3e-49 167.2 17.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF37637.1 - 9.1e-11 42.0 11.1 6.1e-09 36.0 5.6 2.2 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF37637.1 - 1.1e-10 41.3 18.0 1.7e-10 40.7 18.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF37637.1 - 2.8e-06 26.8 22.5 1.5e-05 24.4 22.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF37637.1 - 1.2e-05 25.1 16.9 1.2e-05 25.1 16.9 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MgtE_N PF03448.17 OWF37638.1 - 0.001 19.6 18.3 0.12 13.0 1.1 4.1 1 1 3 4 4 4 3 MgtE intracellular N domain DUF3194 PF11419.8 OWF37638.1 - 0.0014 18.9 13.6 4.1 7.8 1.2 5.8 1 1 3 4 4 4 2 Protein of unknown function (DUF3194) TMEM65 PF10507.9 OWF37638.1 - 0.0087 16.0 35.7 6.8 6.7 1.6 6.0 1 1 4 5 5 5 3 Transmembrane protein 65 DUF2345 PF10106.9 OWF37638.1 - 0.052 13.4 28.1 0.71 9.7 16.2 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) PIF1 PF05970.14 OWF37638.1 - 0.055 12.6 11.2 0.39 9.8 1.4 2.9 1 1 2 3 3 3 0 PIF1-like helicase Arm PF00514.23 OWF37638.1 - 0.1 12.7 24.4 70 3.7 0.1 10.2 3 2 9 13 13 13 0 Armadillo/beta-catenin-like repeat DELLA PF12041.8 OWF37638.1 - 0.13 12.1 24.2 20 5.2 0.4 7.3 1 1 5 6 6 6 0 Transcriptional regulator DELLA protein N terminal GtrA PF04138.14 OWF37638.1 - 0.2 11.9 14.7 0.83 9.9 0.5 4.0 1 1 1 3 3 3 0 GtrA-like protein CBFD_NFYB_HMF PF00808.23 OWF37638.1 - 0.31 11.4 20.9 14 6.1 0.3 5.5 2 1 3 5 5 5 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ATP12 PF07542.11 OWF37638.1 - 2.3 8.3 17.7 1.5e+02 2.4 5.4 4.6 1 1 1 2 2 2 0 ATP12 chaperone protein PMBR PF09373.10 OWF37638.1 - 2.4 8.5 20.6 85 3.6 0.1 8.3 4 4 10 14 14 14 0 Pseudomurein-binding repeat RBFA PF02033.18 OWF37639.1 - 5e-05 23.7 6.3 0.17 12.4 2.3 3.0 1 1 1 2 2 2 2 Ribosome-binding factor A Beta_helix PF13229.6 OWF37639.1 - 2.4 8.0 22.8 4.3 7.2 22.8 1.4 1 1 0 1 1 1 0 Right handed beta helix region BH3 PF15285.6 OWF37640.1 - 0.25 11.1 12.2 16 5.4 0.0 5.6 6 1 0 6 6 6 0 Beclin-1 BH3 domain, Bcl-2-interacting CNOT1_HEAT_N PF16419.5 OWF37640.1 - 1.6 8.4 3.5 19 4.8 0.4 2.7 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF1664 PF07889.12 OWF37641.1 - 3e-17 62.8 2.3 2.8e-05 24.2 0.6 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF1664) DUF948 PF06103.11 OWF37641.1 - 2.2e-10 40.7 14.2 0.011 16.0 2.1 5.4 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF948) SMBP PF16785.5 OWF37641.1 - 4.2e-10 39.8 0.0 0.094 12.9 0.0 5.1 1 1 3 4 4 4 3 Small metal-binding protein TBCC_N PF16752.5 OWF37641.1 - 1e-08 35.6 9.9 0.19 12.2 0.6 6.2 1 1 4 5 5 5 2 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 OWF37641.1 - 1.6e-08 34.7 52.9 0.0049 16.9 18.6 4.4 1 1 3 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus P4Ha_N PF08336.11 OWF37641.1 - 6.1e-08 32.8 35.4 0.18 11.8 1.9 6.3 1 1 4 5 5 5 4 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF5082 PF16888.5 OWF37641.1 - 3.2e-07 30.7 41.9 0.037 14.3 2.3 4.8 1 1 3 4 4 4 3 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 OWF37641.1 - 3.8e-07 30.4 41.3 0.033 14.4 9.5 4.8 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family MCPsignal PF00015.21 OWF37641.1 - 1.5e-06 28.1 0.1 0.66 9.8 0.0 3.8 1 1 3 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain LXG PF04740.12 OWF37641.1 - 8.4e-06 25.6 32.6 0.026 14.3 6.3 4.0 1 1 3 4 4 4 3 LXG domain of WXG superfamily Vps5 PF09325.10 OWF37641.1 - 8.7e-06 25.4 0.6 0.17 11.4 0.2 3.6 1 1 3 4 4 4 2 Vps5 C terminal like NPV_P10 PF05531.12 OWF37641.1 - 8.8e-06 26.1 5.1 8.4 6.9 0.1 5.8 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 OWF37641.1 - 1.1e-05 25.8 0.1 2.7 8.5 0.1 3.9 1 1 2 3 3 3 2 Protein of unknown function DUF16 BLOC1_2 PF10046.9 OWF37641.1 - 7e-05 23.1 40.6 0.0086 16.4 8.3 4.6 1 1 3 5 5 5 4 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.6 OWF37641.1 - 9.1e-05 22.0 16.3 0.074 12.5 7.2 3.6 1 1 2 3 3 3 3 Domain of unknown function (DUF4618) Exonuc_VII_L PF02601.15 OWF37641.1 - 0.00013 21.7 11.7 1.4 8.4 11.7 2.6 1 1 0 1 1 1 1 Exonuclease VII, large subunit DUF3450 PF11932.8 OWF37641.1 - 0.00033 20.0 8.2 0.22 10.8 0.5 4.2 1 1 3 5 5 5 2 Protein of unknown function (DUF3450) Dynactin PF12455.8 OWF37641.1 - 0.001 18.4 24.6 2.7 7.2 11.2 3.8 1 1 0 2 2 2 1 Dynein associated protein Hormone_1 PF00103.20 OWF37641.1 - 0.0013 18.6 25.7 0.34 10.6 1.8 4.0 1 1 4 5 5 5 4 Somatotropin hormone family IF-2B PF01008.17 OWF37641.1 - 0.0017 17.6 16.0 2.2 7.4 1.3 4.4 1 1 3 4 4 4 2 Initiation factor 2 subunit family YlbD_coat PF14071.6 OWF37641.1 - 0.0019 18.5 36.0 0.24 11.7 1.4 6.8 1 1 3 4 4 3 1 Putative coat protein DUF745 PF05335.13 OWF37641.1 - 0.0028 17.4 7.6 1.4 8.6 1.5 4.2 1 1 4 5 5 5 1 Protein of unknown function (DUF745) Serine_rich PF08824.10 OWF37641.1 - 0.003 17.6 0.9 1.5 8.8 0.2 3.2 1 1 2 3 3 3 1 Serine rich protein interaction domain BAR PF03114.18 OWF37641.1 - 0.0055 16.4 25.2 0.026 14.2 7.0 3.2 1 1 3 4 4 4 3 BAR domain ArsA_ATPase PF02374.15 OWF37641.1 - 0.0078 15.4 27.4 0.39 9.8 1.0 4.7 1 1 1 2 2 1 1 Anion-transporting ATPase FPP PF05911.11 OWF37641.1 - 0.01 14.1 17.4 0.13 10.4 16.2 2.1 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil ApoO PF09769.9 OWF37641.1 - 0.012 15.5 16.2 11 6.0 0.3 5.7 1 1 4 5 5 5 0 Apolipoprotein O Lipoprotein_7 PF01540.16 OWF37641.1 - 0.016 14.5 1.9 0.2 10.9 0.9 2.1 1 1 1 2 2 2 0 Adhesin lipoprotein AIP3 PF03915.13 OWF37641.1 - 0.019 14.1 0.4 0.12 11.5 0.4 2.3 1 1 0 1 1 1 0 Actin interacting protein 3 Laminin_II PF06009.12 OWF37641.1 - 0.025 14.6 2.5 1.9 8.5 0.8 3.4 1 1 1 3 3 3 0 Laminin Domain II BAR_3 PF16746.5 OWF37641.1 - 0.028 14.1 36.0 2.8 7.6 24.9 4.4 1 1 1 2 2 2 0 BAR domain of APPL family Perilipin PF03036.16 OWF37641.1 - 0.052 12.6 1.4 0.45 9.5 0.4 2.7 1 1 2 3 3 3 0 Perilipin family YvrJ PF12841.7 OWF37641.1 - 0.055 13.0 0.1 33 4.1 0.0 4.5 3 0 0 3 3 3 0 YvrJ protein family DASH_Dad2 PF08654.10 OWF37641.1 - 0.058 13.8 10.7 5.8 7.4 0.4 4.3 1 1 3 4 4 4 0 DASH complex subunit Dad2 DUF2203 PF09969.9 OWF37641.1 - 0.073 13.8 0.0 9 7.0 0.0 3.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Rogdi_lz PF10259.9 OWF37641.1 - 0.073 12.5 3.9 42 3.5 3.9 3.5 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein HSBP1 PF06825.12 OWF37641.1 - 0.077 12.9 23.1 34 4.4 1.4 7.5 2 2 1 3 3 3 0 Heat shock factor binding protein 1 Noelin-1 PF12308.8 OWF37641.1 - 0.1 12.6 26.9 2 8.4 2.4 5.2 1 1 5 6 6 6 0 Neurogenesis glycoprotein CENP-F_leu_zip PF10473.9 OWF37641.1 - 0.15 12.1 0.0 1.3e+02 2.6 0.0 3.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF842 PF05811.13 OWF37641.1 - 0.16 11.6 8.5 8.2 6.1 7.4 3.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) IZUMO PF15005.6 OWF37641.1 - 0.16 12.4 15.1 1.8 9.0 2.7 3.5 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated GCN5L1 PF06320.13 OWF37641.1 - 0.18 12.0 13.9 6 7.0 1.1 3.6 1 1 3 4 4 4 0 GCN5-like protein 1 (GCN5L1) DUF2990 PF11693.8 OWF37641.1 - 0.24 11.6 27.7 3 8.1 0.4 6.8 1 1 4 5 5 5 0 Protein of unknown function (DUF2990) SseC PF04888.12 OWF37641.1 - 0.32 10.6 17.5 10 5.6 0.1 6.0 1 1 7 8 8 8 0 Secretion system effector C (SseC) like family zf-C4H2 PF10146.9 OWF37641.1 - 0.34 11.2 23.4 0.17 12.2 5.9 3.2 1 1 3 4 4 4 0 Zinc finger-containing protein FliJ PF02050.16 OWF37641.1 - 0.39 10.9 12.2 13 6.0 0.3 4.5 1 1 5 6 6 6 0 Flagellar FliJ protein APG17 PF04108.12 OWF37641.1 - 0.4 9.7 33.9 2.2 7.3 10.6 3.4 1 1 0 2 2 2 0 Autophagy protein Apg17 DegS PF05384.11 OWF37641.1 - 0.47 9.9 14.5 42 3.6 0.3 5.5 1 1 5 6 6 6 0 Sensor protein DegS Flagellar_rod PF05149.12 OWF37641.1 - 0.88 9.0 24.7 8.1 5.8 3.3 4.9 1 1 2 4 4 4 0 Paraflagellar rod protein DUF4795 PF16043.5 OWF37641.1 - 0.98 9.0 10.8 6.5e+02 -0.2 10.8 3.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Tape_meas_lam_C PF09718.10 OWF37641.1 - 1.1 9.4 29.8 72 3.6 0.4 8.2 1 1 4 5 5 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CheZ PF04344.13 OWF37641.1 - 1.2 9.0 16.0 7.4 6.4 4.5 3.2 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ IL7 PF01415.16 OWF37641.1 - 1.3 9.0 39.6 0.3 11.1 10.0 5.1 1 1 3 5 5 5 0 Interleukin 7/9 family PhoU_div PF01865.16 OWF37641.1 - 1.7 7.9 17.8 0.85 8.9 7.0 3.4 1 1 2 3 3 3 0 Protein of unknown function DUF47 Nudc_N PF14050.6 OWF37641.1 - 2.2 8.3 19.0 13 5.8 0.5 5.9 2 2 3 6 6 6 0 N-terminal conserved domain of Nudc. MIP-T3_C PF17749.1 OWF37641.1 - 3 7.8 13.0 11 5.9 6.4 3.2 2 2 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region FAM220 PF15487.6 OWF37641.1 - 3 7.4 15.7 14 5.2 0.2 5.2 1 1 1 4 4 4 0 FAM220 family KNOX2 PF03791.13 OWF37641.1 - 4.7 6.8 18.7 23 4.6 0.1 6.3 4 2 3 8 8 8 0 KNOX2 domain IFT57 PF10498.9 OWF37641.1 - 7.3 5.5 29.3 1.5 7.8 14.2 2.9 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 DUF166 PF02593.14 OWF37641.1 - 8.1 5.9 9.0 8.6 5.8 0.1 4.0 1 1 2 3 3 3 0 Domain of unknown function DUF1664 PF07889.12 OWF37642.1 - 5.3e-05 23.2 0.0 0.0059 16.6 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OWF37642.1 - 0.00026 21.2 11.7 0.069 13.3 1.2 2.2 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OWF37642.1 - 0.00032 20.7 12.5 0.0029 17.7 12.7 2.2 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 OWF37642.1 - 0.0014 18.8 1.7 0.19 12.0 0.2 2.8 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) P4Ha_N PF08336.11 OWF37642.1 - 0.0057 16.7 10.1 0.49 10.4 3.0 3.2 1 1 1 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TBCC_N PF16752.5 OWF37642.1 - 0.0096 16.4 0.7 1.9 8.9 0.1 3.2 1 1 2 3 3 3 1 Tubulin-specific chaperone C N-terminal domain DUF5082 PF16888.5 OWF37642.1 - 0.015 15.6 15.1 0.15 12.3 1.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) IL7 PF01415.16 OWF37642.1 - 0.021 14.8 9.9 1.7 8.7 3.0 2.8 1 1 2 3 3 3 0 Interleukin 7/9 family SMBP PF16785.5 OWF37642.1 - 0.026 14.7 0.0 8.8 6.6 0.0 3.1 1 1 0 2 2 2 0 Small metal-binding protein GCN5L1 PF06320.13 OWF37642.1 - 0.094 12.9 0.7 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FPP PF05911.11 OWF37642.1 - 0.12 10.6 0.9 0.13 10.4 0.9 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Noelin-1 PF12308.8 OWF37642.1 - 0.13 12.3 5.9 2.8 8.0 0.7 3.0 1 1 3 4 4 4 0 Neurogenesis glycoprotein BORCS7 PF16088.5 OWF37642.1 - 0.16 12.2 5.5 0.43 10.9 1.2 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Dynactin PF12455.8 OWF37642.1 - 0.17 11.1 5.1 2.3 7.4 5.0 2.0 1 1 0 1 1 1 0 Dynein associated protein Spore_III_AB PF09548.10 OWF37642.1 - 0.23 11.6 0.8 3 7.9 0.2 2.4 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) ArsA_ATPase PF02374.15 OWF37642.1 - 0.55 9.4 4.6 2.1 7.5 0.8 2.1 1 1 1 2 2 2 0 Anion-transporting ATPase BAR_3 PF16746.5 OWF37642.1 - 0.65 9.7 8.1 0.52 10.0 2.6 2.3 1 1 1 2 2 2 0 BAR domain of APPL family Ins_allergen_rp PF06757.13 OWF37642.1 - 2 8.3 12.4 9.4e+02 -0.4 12.4 3.3 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification DUF2990 PF11693.8 OWF37642.1 - 4.9 7.4 9.9 2.9 8.1 0.7 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2990) BLOC1_2 PF10046.9 OWF37642.1 - 5.6 7.3 10.5 9.1 6.7 3.6 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Helicase_C_4 PF13871.6 OWF37642.1 - 6.1 6.4 5.1 15 5.2 5.1 1.7 1 1 0 1 1 1 0 C-terminal domain on Strawberry notch homologue APG17 PF04108.12 OWF37642.1 - 6.5 5.8 10.0 18 4.3 10.0 1.8 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF948 PF06103.11 OWF37643.1 - 3.2e-05 24.1 4.0 0.0083 16.4 2.7 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OWF37643.1 - 3.8e-05 23.7 0.2 5.7e-05 23.1 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) TBCC_N PF16752.5 OWF37643.1 - 7.3e-05 23.2 2.6 0.97 9.9 0.2 3.0 1 1 2 3 3 3 2 Tubulin-specific chaperone C N-terminal domain KNOX2 PF03791.13 OWF37643.1 - 9e-05 21.9 0.9 0.1 12.1 0.1 3.0 1 1 2 3 3 3 2 KNOX2 domain P4Ha_N PF08336.11 OWF37643.1 - 0.00011 22.2 5.1 0.084 12.9 1.6 2.6 1 1 0 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fib_alpha PF08702.10 OWF37643.1 - 0.0002 21.6 7.1 0.00051 20.2 7.1 1.7 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 OWF37643.1 - 0.00047 20.6 0.6 0.49 10.9 0.1 2.3 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein SMBP PF16785.5 OWF37643.1 - 0.0015 18.7 0.2 0.015 15.5 0.2 2.3 1 1 0 1 1 1 1 Small metal-binding protein Tektin PF03148.14 OWF37643.1 - 0.0021 16.9 3.0 0.0024 16.7 3.0 1.0 1 0 0 1 1 1 1 Tektin family IDO PF01231.18 OWF37643.1 - 0.0022 16.8 6.0 0.2 10.4 1.2 2.0 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase Biopterin_H PF00351.21 OWF37643.1 - 0.0033 16.5 0.5 0.0036 16.4 0.5 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase BLOC1_2 PF10046.9 OWF37643.1 - 0.0051 17.1 9.6 0.0087 16.3 9.4 1.5 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.21 OWF37643.1 - 0.0053 16.6 0.0 0.006 16.4 0.0 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 OWF37643.1 - 0.01 15.9 17.1 0.024 14.7 17.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.13 OWF37643.1 - 0.012 15.3 0.9 0.03 14.0 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 OWF37643.1 - 0.014 15.0 1.1 0.015 14.9 1.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG17 PF04108.12 OWF37643.1 - 0.017 14.2 3.8 0.022 13.9 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Matrilin_ccoil PF10393.9 OWF37643.1 - 0.019 14.8 0.0 8.2 6.4 0.0 3.1 2 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Glutaredoxin2_C PF04399.13 OWF37643.1 - 0.019 14.8 2.7 0.35 10.7 0.5 2.2 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Tape_meas_lam_C PF09718.10 OWF37643.1 - 0.021 14.9 4.7 4.7 7.4 0.3 3.2 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RecG_N PF17190.4 OWF37643.1 - 0.025 15.3 2.3 0.43 11.3 0.6 2.5 1 1 1 2 2 2 0 RecG N-terminal helical domain DegS PF05384.11 OWF37643.1 - 0.026 14.0 1.6 1.6 8.2 1.2 2.4 1 1 1 2 2 2 0 Sensor protein DegS PHA_synth_III_E PF09712.10 OWF37643.1 - 0.033 13.3 1.2 0.042 12.9 1.2 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) SKA1 PF07160.12 OWF37643.1 - 0.033 14.0 4.8 0.16 11.8 4.3 1.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF773 PF05600.12 OWF37643.1 - 0.034 12.9 0.9 0.039 12.7 0.9 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Transpos_assoc PF13963.6 OWF37643.1 - 0.038 14.3 5.3 0.32 11.3 1.7 2.3 1 1 1 2 2 2 0 Transposase-associated domain DUF5082 PF16888.5 OWF37643.1 - 0.042 14.1 6.8 0.38 11.0 6.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4939 PF16297.5 OWF37643.1 - 0.048 13.5 6.2 1.5 8.7 0.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4939) IFT57 PF10498.9 OWF37643.1 - 0.061 12.3 5.4 0.084 11.8 5.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF640 PF04852.12 OWF37643.1 - 0.064 13.4 1.4 7.8 6.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF640) Fzo_mitofusin PF04799.13 OWF37643.1 - 0.072 12.6 2.0 0.1 12.1 2.0 1.4 1 0 0 1 1 1 0 fzo-like conserved region Vps5 PF09325.10 OWF37643.1 - 0.073 12.6 0.1 0.14 11.6 0.1 1.4 1 1 0 1 1 1 0 Vps5 C terminal like IL7 PF01415.16 OWF37643.1 - 0.096 12.7 12.0 0.51 10.4 9.9 2.0 1 1 1 2 2 2 0 Interleukin 7/9 family DUF913 PF06025.12 OWF37643.1 - 0.11 11.4 15.2 0.2 10.6 1.9 2.9 1 1 2 3 3 3 0 Domain of Unknown Function (DUF913) LXG PF04740.12 OWF37643.1 - 0.13 12.0 8.0 0.47 10.1 1.7 2.1 1 1 2 3 3 3 0 LXG domain of WXG superfamily BAR_3 PF16746.5 OWF37643.1 - 0.15 11.7 8.9 0.65 9.7 8.9 1.9 1 1 0 1 1 1 0 BAR domain of APPL family FPP PF05911.11 OWF37643.1 - 0.16 10.2 3.4 0.16 10.1 3.4 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil IF-2B PF01008.17 OWF37643.1 - 0.16 11.1 2.1 0.35 10.0 2.1 1.6 1 1 0 1 1 1 0 Initiation factor 2 subunit family Dynactin PF12455.8 OWF37643.1 - 0.21 10.8 5.7 0.4 9.9 5.7 1.6 1 1 0 1 1 1 0 Dynein associated protein Not3 PF04065.15 OWF37643.1 - 0.22 10.9 2.2 0.3 10.5 2.2 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Sec20 PF03908.13 OWF37643.1 - 0.22 11.4 2.7 0.29 11.1 1.6 1.7 1 1 0 1 1 1 0 Sec20 mCpol PF18182.1 OWF37643.1 - 0.23 11.8 1.2 19 5.6 0.1 2.6 1 1 1 2 2 2 0 minimal CRISPR polymerase domain ArsA_ATPase PF02374.15 OWF37643.1 - 0.24 10.5 4.3 0.75 8.9 4.3 1.8 1 1 0 1 1 1 0 Anion-transporting ATPase ApoO PF09769.9 OWF37643.1 - 0.25 11.3 2.8 11 5.9 0.3 2.7 1 1 2 3 3 3 0 Apolipoprotein O Flagellar_rod PF05149.12 OWF37643.1 - 0.25 10.8 4.1 0.85 9.0 1.1 2.0 1 1 1 2 2 2 0 Paraflagellar rod protein Med16 PF11635.8 OWF37643.1 - 0.31 8.9 11.5 4.4 5.1 11.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 16 DUF2990 PF11693.8 OWF37643.1 - 0.46 10.7 4.8 14 6.0 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2990) BRCA-2_OB3 PF09104.10 OWF37643.1 - 0.58 9.8 5.7 14 5.3 0.5 2.6 1 1 2 3 3 3 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 ANAPC4 PF12896.7 OWF37643.1 - 0.62 9.5 13.7 0.75 9.2 6.9 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 AI-2E_transport PF01594.16 OWF37643.1 - 0.64 9.1 9.8 2.3 7.3 9.8 1.8 1 1 0 1 1 1 0 AI-2E family transporter aGPT-Pplase3 PF18746.1 OWF37643.1 - 0.87 8.9 8.3 2.8 7.2 8.3 1.8 1 1 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Cut8 PF08559.10 OWF37643.1 - 1.2 8.7 18.9 4.8e+02 0.2 18.7 2.7 1 1 0 1 1 1 0 Cut8, nuclear proteasome tether protein Noelin-1 PF12308.8 OWF37643.1 - 1.5 8.8 5.4 2.7 8.0 2.1 2.4 1 1 2 3 3 3 0 Neurogenesis glycoprotein Col_cuticle_N PF01484.17 OWF37643.1 - 1.6 8.8 20.2 0.99 9.5 2.4 3.5 2 1 0 3 3 3 0 Nematode cuticle collagen N-terminal domain RecQ_Zn_bind PF16124.5 OWF37643.1 - 1.8 9.4 11.1 1.4e+02 3.3 8.1 3.8 1 1 1 2 2 2 0 RecQ zinc-binding DUF3754 PF12576.8 OWF37643.1 - 2.1 8.3 8.8 5.1 7.1 1.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3754) MSA-2c PF12238.8 OWF37643.1 - 2.6 8.0 8.3 7.9 6.4 4.4 2.1 1 1 1 2 2 2 0 Merozoite surface antigen 2c zf-TAZ PF02135.16 OWF37643.1 - 8.2 7.0 10.5 3.3e+02 1.8 10.5 3.0 1 1 0 1 1 1 0 TAZ zinc finger DUF1043 PF06295.12 OWF37643.1 - 10 6.2 12.5 10 6.2 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 OWF37644.1 - 1.1e-12 48.0 0.0 0.0016 18.5 0.0 3.6 1 1 1 3 3 3 3 Protein of unknown function (DUF1664) DUF948 PF06103.11 OWF37644.1 - 4.6e-12 46.0 4.1 0.0093 16.2 1.0 4.8 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 OWF37644.1 - 8.8e-09 35.7 28.1 0.0033 17.6 8.6 4.6 1 1 4 5 5 5 5 Fibrinogen alpha/beta chain family TBCC_N PF16752.5 OWF37644.1 - 1.3e-08 35.3 4.0 0.29 11.6 0.0 5.6 1 1 5 6 6 6 2 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 OWF37644.1 - 4.7e-08 33.2 31.5 0.055 13.5 20.7 3.8 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus P4Ha_N PF08336.11 OWF37644.1 - 1.1e-06 28.6 25.0 0.15 12.1 2.7 5.6 1 1 3 4 4 4 3 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NPV_P10 PF05531.12 OWF37644.1 - 2.1e-06 28.1 1.0 6.9 7.2 0.1 5.2 1 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 OWF37644.1 - 1.4e-05 25.4 29.5 0.091 13.0 4.6 4.2 1 1 3 4 4 4 4 Domain of unknown function (DUF5082) SMBP PF16785.5 OWF37644.1 - 1.5e-05 25.2 0.1 0.29 11.4 0.0 4.2 2 2 3 5 5 5 1 Small metal-binding protein Tektin PF03148.14 OWF37644.1 - 4.9e-05 22.3 3.2 0.035 12.9 0.4 3.1 1 1 2 3 3 3 1 Tektin family MtrB PF05440.12 OWF37644.1 - 8.2e-05 22.9 7.2 0.97 9.9 0.1 4.4 2 2 2 4 4 4 1 Tetrahydromethanopterin S-methyltransferase subunit B MCPsignal PF00015.21 OWF37644.1 - 0.00016 21.5 0.0 5 6.9 0.0 3.2 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4618 PF15397.6 OWF37644.1 - 0.00021 20.8 6.5 0.24 10.8 2.1 3.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) DUF745 PF05335.13 OWF37644.1 - 0.00022 21.0 0.1 5.4 6.7 0.1 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 OWF37644.1 - 0.00034 20.3 3.2 0.058 13.0 0.6 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit DUF16 PF01519.16 OWF37644.1 - 0.00069 20.1 0.0 1.2 9.7 0.0 3.2 1 1 1 2 2 2 1 Protein of unknown function DUF16 Noelin-1 PF12308.8 OWF37644.1 - 0.0017 18.3 16.8 2.5 8.1 0.4 4.8 1 1 3 4 4 4 1 Neurogenesis glycoprotein IF-2B PF01008.17 OWF37644.1 - 0.0018 17.6 6.2 0.4 9.9 0.4 3.4 1 1 2 3 3 3 1 Initiation factor 2 subunit family DUF3450 PF11932.8 OWF37644.1 - 0.0019 17.5 0.7 1.8 7.8 0.1 3.3 1 1 4 5 5 5 1 Protein of unknown function (DUF3450) Med11 PF10280.9 OWF37644.1 - 0.0037 17.7 1.0 6.8 7.2 0.3 4.0 2 2 0 2 2 2 0 Mediator complex protein FPP PF05911.11 OWF37644.1 - 0.0048 15.2 7.5 0.047 11.9 2.1 2.0 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil Dynactin PF12455.8 OWF37644.1 - 0.0049 16.1 13.1 0.12 11.6 1.5 3.2 1 1 2 3 3 3 2 Dynein associated protein APG17 PF04108.12 OWF37644.1 - 0.016 14.4 27.4 0.15 11.2 3.7 3.1 1 1 2 3 3 3 0 Autophagy protein Apg17 PHA_synth_III_E PF09712.10 OWF37644.1 - 0.017 14.3 15.1 0.055 12.6 4.8 2.5 1 1 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Vps5 PF09325.10 OWF37644.1 - 0.017 14.7 0.0 3.5 7.1 0.0 3.0 1 1 2 3 3 3 0 Vps5 C terminal like Laminin_II PF06009.12 OWF37644.1 - 0.02 14.9 0.0 5.3 7.0 0.0 2.7 1 1 3 4 4 4 0 Laminin Domain II SseC PF04888.12 OWF37644.1 - 0.021 14.5 4.2 34 3.9 0.1 4.7 2 2 5 7 7 7 0 Secretion system effector C (SseC) like family Collagen_mid PF15984.5 OWF37644.1 - 0.021 14.6 0.0 6.1 6.5 0.0 2.5 1 1 0 2 2 2 0 Bacterial collagen, middle region IL7 PF01415.16 OWF37644.1 - 0.021 14.8 22.3 0.33 11.0 6.6 4.0 1 1 4 5 5 5 0 Interleukin 7/9 family GCN5L1 PF06320.13 OWF37644.1 - 0.033 14.3 4.4 0.75 10.0 0.5 3.0 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) ArsA_ATPase PF02374.15 OWF37644.1 - 0.068 12.3 17.2 1 8.4 1.4 4.1 1 1 3 4 4 4 0 Anion-transporting ATPase LXG PF04740.12 OWF37644.1 - 0.097 12.4 24.6 2.9 7.6 5.9 3.7 1 1 2 3 3 3 0 LXG domain of WXG superfamily ApoO PF09769.9 OWF37644.1 - 0.11 12.4 13.3 18 5.3 0.1 4.8 1 1 1 3 3 3 0 Apolipoprotein O zf-C4H2 PF10146.9 OWF37644.1 - 0.27 11.5 12.4 2.1 8.6 0.8 2.9 1 1 3 4 4 4 0 Zinc finger-containing protein BLOC1_2 PF10046.9 OWF37644.1 - 0.42 11.0 27.6 9.3 6.6 11.0 4.1 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.16 OWF37644.1 - 0.42 10.8 4.1 9.8 6.4 0.1 3.6 1 1 3 4 4 4 0 Flagellar FliJ protein Flagellar_rod PF05149.12 OWF37644.1 - 0.56 9.6 16.3 5.4 6.4 1.8 4.2 1 1 2 4 4 4 0 Paraflagellar rod protein DASH_Dad2 PF08654.10 OWF37644.1 - 0.58 10.6 2.1 15 6.1 0.3 3.6 1 1 2 3 3 3 0 DASH complex subunit Dad2 SPICE PF15678.5 OWF37644.1 - 0.61 9.4 2.0 2.6 7.3 0.1 2.1 2 0 0 2 2 2 0 Centriole duplication and mitotic chromosome congression CDC24 PF06395.11 OWF37644.1 - 0.81 10.0 10.7 16 5.9 0.2 3.8 2 2 1 4 4 4 0 CDC24 Calponin DUF2990 PF11693.8 OWF37644.1 - 1.1 9.5 26.8 8.1 6.7 0.3 6.7 2 2 4 6 6 6 0 Protein of unknown function (DUF2990) IFT57 PF10498.9 OWF37644.1 - 1.5 7.7 19.5 0.33 9.9 3.7 2.7 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 BAR_3 PF16746.5 OWF37644.1 - 2.3 7.8 26.1 47 3.6 19.9 3.9 1 1 0 1 1 1 0 BAR domain of APPL family CheZ PF04344.13 OWF37644.1 - 2.9 7.8 6.6 8.1 6.3 1.5 2.7 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ BAR PF03114.18 OWF37644.1 - 4.8 6.7 19.3 5.4 6.6 5.3 4.1 1 1 1 2 2 1 0 BAR domain KNOX2 PF03791.13 OWF37644.1 - 5.3 6.6 12.6 41 3.8 0.1 5.4 2 2 2 6 6 6 0 KNOX2 domain DUF1664 PF07889.12 OWF37646.1 - 6.8e-21 74.6 5.9 0.0013 18.8 0.1 5.5 1 1 4 5 5 5 5 Protein of unknown function (DUF1664) TBCC_N PF16752.5 OWF37646.1 - 1.8e-14 54.2 16.4 0.33 11.4 0.1 8.1 1 1 6 7 7 7 5 Tubulin-specific chaperone C N-terminal domain SMBP PF16785.5 OWF37646.1 - 1.9e-12 47.4 4.8 0.01 16.0 0.2 7.1 1 1 7 8 8 8 4 Small metal-binding protein DUF948 PF06103.11 OWF37646.1 - 1.3e-10 41.4 31.6 0.12 12.6 1.0 7.4 1 1 3 5 5 5 4 Bacterial protein of unknown function (DUF948) P4Ha_N PF08336.11 OWF37646.1 - 4.5e-10 39.7 52.5 0.059 13.4 0.8 8.2 2 2 6 8 8 8 7 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fib_alpha PF08702.10 OWF37646.1 - 2.7e-09 37.4 59.0 0.21 11.8 8.2 6.5 1 1 4 6 6 6 5 Fibrinogen alpha/beta chain family MCPsignal PF00015.21 OWF37646.1 - 2.7e-09 37.1 0.0 0.88 9.4 0.0 4.7 1 1 5 6 6 6 3 Methyl-accepting chemotaxis protein (MCP) signalling domain Matrilin_ccoil PF10393.9 OWF37646.1 - 2.7e-09 36.7 0.0 11 6.0 0.0 9.7 6 4 4 11 11 10 0 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 OWF37646.1 - 5.2e-09 36.3 77.2 0.05 13.6 9.3 5.9 1 1 4 5 5 5 5 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 OWF37646.1 - 2.3e-07 31.2 3.0 1.3 9.5 0.2 5.0 1 1 3 4 4 4 2 Protein of unknown function DUF16 IL7 PF01415.16 OWF37646.1 - 1.7e-06 28.1 60.5 0.013 15.5 5.3 6.3 1 1 5 6 6 6 4 Interleukin 7/9 family DUF745 PF05335.13 OWF37646.1 - 1.9e-06 27.7 17.8 0.041 13.6 0.7 5.8 1 1 5 7 7 7 2 Protein of unknown function (DUF745) DUF3450 PF11932.8 OWF37646.1 - 1.3e-05 24.7 8.6 4.2 6.6 0.2 5.3 1 1 4 6 6 6 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 OWF37646.1 - 2.5e-05 24.5 54.3 0.1 12.9 6.6 5.5 1 1 5 7 7 7 5 Domain of unknown function (DUF5082) PSII_Pbs27 PF13326.6 OWF37646.1 - 3.6e-05 24.1 0.0 10 6.4 0.0 5.8 1 1 1 3 3 3 0 Photosystem II Pbs27 Exonuc_VII_L PF02601.15 OWF37646.1 - 5.1e-05 23.0 26.4 0.068 12.7 1.2 3.8 1 1 1 2 2 1 1 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 OWF37646.1 - 8.1e-05 22.7 0.0 4.6 7.3 0.0 4.8 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hormone_1 PF00103.20 OWF37646.1 - 9.7e-05 22.2 38.5 0.043 13.6 4.2 5.1 1 1 4 5 5 5 4 Somatotropin hormone family Collagen_mid PF15984.5 OWF37646.1 - 0.00011 22.1 0.0 2.5 7.8 0.0 3.6 1 1 3 4 4 4 1 Bacterial collagen, middle region DUF4618 PF15397.6 OWF37646.1 - 0.00011 21.8 25.9 0.52 9.7 8.4 5.1 1 1 2 4 4 4 2 Domain of unknown function (DUF4618) SKA1 PF07160.12 OWF37646.1 - 0.00012 22.0 37.4 0.38 10.6 0.8 5.5 1 1 4 5 5 5 3 Spindle and kinetochore-associated protein 1 BAR_3 PF16746.5 OWF37646.1 - 0.00099 18.9 50.4 0.23 11.1 6.5 5.3 1 1 4 5 5 5 2 BAR domain of APPL family FPP PF05911.11 OWF37646.1 - 0.0018 16.6 30.1 0.13 10.4 25.3 3.0 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil DegS PF05384.11 OWF37646.1 - 0.0021 17.6 16.5 1.1 8.8 0.2 6.4 1 1 6 7 7 7 1 Sensor protein DegS Serine_rich PF08824.10 OWF37646.1 - 0.0053 16.8 6.3 4.4 7.3 0.6 4.1 1 1 3 4 4 4 0 Serine rich protein interaction domain Goodbye PF17109.5 OWF37646.1 - 0.007 16.8 0.3 4.7 7.7 0.0 4.5 2 2 3 5 5 5 0 fungal STAND N-terminal Goodbye domain Glutaredoxin2_C PF04399.13 OWF37646.1 - 0.011 15.6 26.8 1.1 9.2 3.5 6.8 1 1 6 7 7 7 0 Glutaredoxin 2, C terminal domain Laminin_II PF06009.12 OWF37646.1 - 0.013 15.5 7.5 8.2 6.4 0.3 4.3 1 1 4 5 5 5 0 Laminin Domain II DHR10 PF18595.1 OWF37646.1 - 0.021 14.9 0.0 50 4.0 0.0 4.0 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain SseC PF04888.12 OWF37646.1 - 0.021 14.4 16.6 1.2 8.7 0.3 6.7 1 1 5 8 8 8 0 Secretion system effector C (SseC) like family AIP3 PF03915.13 OWF37646.1 - 0.035 13.2 8.9 0.38 9.8 2.4 3.3 1 1 0 2 2 2 0 Actin interacting protein 3 YscO-like PF16789.5 OWF37646.1 - 0.083 12.9 8.5 0.82 9.7 0.1 4.6 1 1 3 6 6 6 0 YscO-like protein mCpol PF18182.1 OWF37646.1 - 0.097 13.0 19.7 6.7 7.1 0.4 7.3 1 1 4 6 6 6 0 minimal CRISPR polymerase domain ApoLp-III PF07464.11 OWF37646.1 - 0.1 12.7 9.0 5.1 7.2 0.3 4.6 2 1 2 5 5 5 0 Apolipophorin-III precursor (apoLp-III) HemX PF04375.14 OWF37646.1 - 0.12 11.6 0.3 13 4.9 0.3 3.3 2 1 1 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase GCN5L1 PF06320.13 OWF37646.1 - 0.16 12.1 21.6 1.5 9.0 1.2 4.8 1 1 6 7 7 7 0 GCN5-like protein 1 (GCN5L1) FapA PF03961.13 OWF37646.1 - 0.19 10.3 16.4 1.7 7.2 1.0 4.1 1 1 4 5 5 5 0 Flagellar Assembly Protein A DUF2408 PF10303.9 OWF37646.1 - 0.24 11.9 9.8 23 5.5 3.2 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Lebercilin PF15619.6 OWF37646.1 - 0.52 9.9 7.9 8.7 5.9 0.2 3.8 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 OWF37646.1 - 0.65 9.4 3.9 2.8 7.4 0.7 2.6 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal ArsA_ATPase PF02374.15 OWF37646.1 - 0.66 9.1 35.2 3.8 6.6 1.6 6.0 1 1 5 6 6 6 0 Anion-transporting ATPase LXG PF04740.12 OWF37646.1 - 0.83 9.3 49.1 0.4 10.4 4.5 5.6 1 1 5 6 6 6 0 LXG domain of WXG superfamily APG17 PF04108.12 OWF37646.1 - 1 8.4 51.6 1.8 7.6 29.2 4.3 1 1 1 3 3 3 0 Autophagy protein Apg17 YlbD_coat PF14071.6 OWF37646.1 - 1.2 9.4 45.9 8.7 6.6 0.5 8.4 1 1 5 6 6 5 0 Putative coat protein CortBP2 PF09727.9 OWF37646.1 - 1.3 8.9 21.4 1.6 8.6 0.6 5.0 1 1 4 6 6 6 0 Cortactin-binding protein-2 PHA_synth_III_E PF09712.10 OWF37646.1 - 2 7.4 34.3 5.8 5.9 5.3 4.2 1 1 4 5 5 5 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Noelin-1 PF12308.8 OWF37646.1 - 2.9 7.9 38.1 3.1 7.8 1.9 6.7 1 1 7 8 8 8 0 Neurogenesis glycoprotein DUF2990 PF11693.8 OWF37646.1 - 3.1 8.0 39.2 11 6.3 0.8 9.5 1 1 7 10 10 10 0 Protein of unknown function (DUF2990) DASH_Dad2 PF08654.10 OWF37646.1 - 3.2 8.2 18.2 4.6 7.7 0.7 5.6 1 1 4 5 5 5 0 DASH complex subunit Dad2 Lipoprotein_20 PF13942.6 OWF37646.1 - 3.6 7.5 9.2 20 5.0 0.0 4.6 3 2 3 6 6 5 0 YfhG lipoprotein Tape_meas_lam_C PF09718.10 OWF37646.1 - 7.2 6.8 35.2 10 6.3 1.0 9.9 2 2 6 9 9 9 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) KNOX2 PF03791.13 OWF37646.1 - 9.8 5.8 26.1 2.3 7.8 0.1 7.6 7 1 2 9 9 9 0 KNOX2 domain DUF1664 PF07889.12 OWF37647.1 - 9.5e-16 58.0 0.0 0.00092 19.3 0.1 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OWF37647.1 - 4.9e-11 42.8 36.3 0.00041 20.4 14.2 4.4 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus TBCC_N PF16752.5 OWF37647.1 - 1.7e-10 41.3 3.3 0.0033 17.9 0.2 5.4 1 1 7 8 8 8 3 Tubulin-specific chaperone C N-terminal domain SMBP PF16785.5 OWF37647.1 - 2.4e-10 40.6 0.2 0.029 14.6 0.0 5.7 1 1 3 4 4 4 3 Small metal-binding protein Fib_alpha PF08702.10 OWF37647.1 - 1.5e-07 31.7 32.6 0.0046 17.1 4.8 4.7 1 1 4 5 5 5 4 Fibrinogen alpha/beta chain family DUF948 PF06103.11 OWF37647.1 - 4.2e-07 30.1 7.2 0.28 11.5 0.7 4.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) P4Ha_N PF08336.11 OWF37647.1 - 8.5e-07 29.1 32.0 0.19 11.8 1.0 6.2 1 1 3 4 4 4 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NPV_P10 PF05531.12 OWF37647.1 - 2.6e-06 27.8 2.3 1.4 9.4 0.1 6.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 OWF37647.1 - 6.9e-06 26.0 0.0 1.8 8.4 0.0 3.9 1 1 3 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA1 PF07160.12 OWF37647.1 - 8.5e-06 25.8 12.7 0.22 11.3 0.4 4.3 1 1 4 5 5 5 2 Spindle and kinetochore-associated protein 1 DUF745 PF05335.13 OWF37647.1 - 1.9e-05 24.4 0.9 0.11 12.3 0.1 3.2 1 1 1 3 3 3 2 Protein of unknown function (DUF745) DUF16 PF01519.16 OWF37647.1 - 5.8e-05 23.5 0.1 0.72 10.4 0.0 3.3 1 1 1 3 3 3 2 Protein of unknown function DUF16 DUF3450 PF11932.8 OWF37647.1 - 5.9e-05 22.5 0.3 1.1 8.6 0.0 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) Hormone_1 PF00103.20 OWF37647.1 - 7.8e-05 22.5 15.9 0.33 10.7 0.8 4.5 1 1 3 4 4 4 2 Somatotropin hormone family Exonuc_VII_L PF02601.15 OWF37647.1 - 0.00012 21.8 6.0 0.55 9.8 6.1 2.2 1 1 0 1 1 1 1 Exonuclease VII, large subunit Tektin PF03148.14 OWF37647.1 - 0.00023 20.1 7.9 0.049 12.4 1.9 2.9 2 1 1 3 3 3 2 Tektin family Matrilin_ccoil PF10393.9 OWF37647.1 - 0.00024 20.9 0.0 14 5.6 0.0 5.9 4 2 3 7 7 6 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF5082 PF16888.5 OWF37647.1 - 0.00094 19.5 39.6 1.3 9.3 5.8 5.3 1 1 4 5 5 5 3 Domain of unknown function (DUF5082) IL7 PF01415.16 OWF37647.1 - 0.00095 19.2 28.6 0.0048 16.9 4.4 4.5 1 1 3 4 4 4 1 Interleukin 7/9 family Med11 PF10280.9 OWF37647.1 - 0.00098 19.6 3.6 10 6.6 0.1 5.1 2 2 2 4 4 4 0 Mediator complex protein IF-2B PF01008.17 OWF37647.1 - 0.003 16.8 8.4 0.89 8.7 2.3 3.7 1 1 1 2 2 2 2 Initiation factor 2 subunit family mCpol PF18182.1 OWF37647.1 - 0.0054 17.0 10.5 4.8 7.6 0.1 6.1 1 1 3 4 4 4 0 minimal CRISPR polymerase domain Vps5 PF09325.10 OWF37647.1 - 0.0068 16.0 0.0 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Vps5 C terminal like ArsA_ATPase PF02374.15 OWF37647.1 - 0.018 14.2 14.3 3.8 6.6 0.7 4.2 1 1 1 2 2 2 0 Anion-transporting ATPase DegS PF05384.11 OWF37647.1 - 0.022 14.2 5.6 9.9 5.6 0.2 4.4 1 1 2 4 4 4 0 Sensor protein DegS FPP PF05911.11 OWF37647.1 - 0.023 12.9 11.6 0.13 10.4 8.8 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil SseC PF04888.12 OWF37647.1 - 0.023 14.3 2.0 8.2 5.9 0.0 3.6 2 2 2 4 4 4 0 Secretion system effector C (SseC) like family FapA PF03961.13 OWF37647.1 - 0.025 13.2 6.5 0.22 10.1 0.8 2.1 1 1 0 2 2 2 0 Flagellar Assembly Protein A Perilipin PF03036.16 OWF37647.1 - 0.038 13.0 0.3 12 4.8 0.0 3.0 2 2 1 3 3 3 0 Perilipin family APG17 PF04108.12 OWF37647.1 - 0.039 13.1 33.2 0.079 12.1 5.3 3.3 1 1 2 3 3 3 0 Autophagy protein Apg17 YlbD_coat PF14071.6 OWF37647.1 - 0.054 13.7 20.2 11 6.2 2.3 5.8 1 1 3 4 4 4 0 Putative coat protein Laminin_II PF06009.12 OWF37647.1 - 0.075 13.0 0.1 17 5.5 0.1 2.7 1 1 2 3 3 3 0 Laminin Domain II DASH_Dad2 PF08654.10 OWF37647.1 - 0.095 13.1 2.7 15 6.0 0.1 3.5 1 1 0 2 2 2 0 DASH complex subunit Dad2 GCN5L1 PF06320.13 OWF37647.1 - 0.12 12.5 7.6 2.9 8.1 1.3 2.8 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Snapin_Pallidin PF14712.6 OWF37647.1 - 0.15 12.5 11.5 0.31 11.5 0.3 4.1 1 1 3 5 5 4 0 Snapin/Pallidin DUF725 PF05267.12 OWF37647.1 - 0.3 11.1 19.4 1.1 9.2 3.3 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF725) BAR PF03114.18 OWF37647.1 - 0.35 10.5 22.2 1.5 8.4 3.7 4.0 1 1 1 2 2 2 0 BAR domain ADIP PF11559.8 OWF37647.1 - 0.39 10.8 7.4 1.1 9.3 0.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CortBP2 PF09727.9 OWF37647.1 - 0.45 10.4 6.7 2.3 8.1 0.5 2.9 2 2 1 3 3 3 0 Cortactin-binding protein-2 LXG PF04740.12 OWF37647.1 - 0.47 10.1 28.4 4.8 6.8 7.6 4.6 1 1 3 4 4 4 0 LXG domain of WXG superfamily FH2 PF02181.23 OWF37647.1 - 0.51 9.4 7.8 2.5 7.1 0.3 2.7 1 1 1 2 2 2 0 Formin Homology 2 Domain Rogdi_lz PF10259.9 OWF37647.1 - 0.73 9.2 5.5 5.4 6.4 0.3 3.1 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein Noelin-1 PF12308.8 OWF37647.1 - 0.89 9.6 17.9 2.2 8.3 1.6 5.0 1 1 6 7 7 7 0 Neurogenesis glycoprotein ApoO PF09769.9 OWF37647.1 - 1.1 9.3 17.5 7 6.6 0.2 5.5 1 1 2 4 4 4 0 Apolipoprotein O BAR_3 PF16746.5 OWF37647.1 - 1.1 8.9 31.5 21 4.7 1.9 4.3 1 1 2 3 3 3 0 BAR domain of APPL family Nudc_N PF14050.6 OWF37647.1 - 1.2 9.2 26.7 1.7 8.7 0.7 5.9 1 1 6 7 7 7 0 N-terminal conserved domain of Nudc. IFT57 PF10498.9 OWF37647.1 - 1.3 7.9 21.6 0.68 8.8 6.2 2.8 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 OWF37647.1 - 3.2 8.1 32.7 2.7 8.4 7.3 4.5 1 1 5 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 OWF37647.1 - 3.8 7.8 16.6 4.8 7.4 4.1 3.0 1 1 0 2 2 2 0 Zinc finger-containing protein KNOX2 PF03791.13 OWF37647.1 - 4.5 6.9 10.1 31 4.2 0.1 4.9 2 2 2 5 5 5 0 KNOX2 domain BAF250_C PF12031.8 OWF37648.1 - 1.2e-109 365.6 0.9 1.9e-109 364.9 0.9 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 OWF37648.1 - 8.3e-17 61.6 0.0 1.8e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF228 PF02989.14 OWF37648.1 - 0.19 11.5 1.7 0.4 10.5 1.7 1.5 1 0 0 1 1 1 0 Lyme disease proteins of unknown function MCLC PF05934.11 OWF37648.1 - 3.5 6.2 5.7 7.6 5.1 5.7 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) AAA_30 PF13604.6 OWF37649.1 - 5.5e-28 98.0 0.0 9.9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF37649.1 - 7.8e-16 58.7 0.0 2.9e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OWF37649.1 - 4.9e-14 52.6 1.6 1.4e-06 28.2 0.2 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 OWF37649.1 - 1.8e-08 34.0 0.0 3.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 OWF37649.1 - 1.1e-06 28.4 0.2 3.1e-06 26.9 0.2 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 OWF37649.1 - 2.1e-05 24.4 8.2 0.018 14.9 0.0 2.9 4 0 0 4 4 2 2 AAA domain AAA_14 PF13173.6 OWF37649.1 - 0.0051 16.9 0.0 0.035 14.1 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF37649.1 - 0.0076 16.5 0.1 0.038 14.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain PhoH PF02562.16 OWF37649.1 - 0.011 15.2 0.3 0.049 13.1 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 OWF37649.1 - 0.012 14.9 0.4 0.029 13.6 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 OWF37649.1 - 0.012 16.0 0.0 0.065 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Helicase_RecD PF05127.14 OWF37649.1 - 0.028 14.3 0.3 0.2 11.5 0.3 2.2 1 1 0 1 1 1 0 Helicase Rad17 PF03215.15 OWF37649.1 - 0.072 13.0 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain Herpes_Helicase PF02689.14 OWF37649.1 - 0.09 10.7 0.0 2.6 5.9 0.0 2.6 3 0 0 3 3 3 0 Helicase NACHT PF05729.12 OWF37649.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ras PF00071.22 OWF37649.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Ras family AAA PF00004.29 OWF37649.1 - 0.15 12.5 0.3 0.55 10.7 0.0 2.2 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ParA PF10609.9 OWF37649.1 - 0.16 11.4 1.2 0.3 10.5 1.2 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Roc PF08477.13 OWF37649.1 - 0.16 12.2 0.5 0.56 10.4 0.2 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 OWF37649.1 - 0.21 11.7 4.6 0.12 12.4 2.1 2.0 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OWF37649.1 - 0.92 8.6 4.7 11 5.1 4.5 2.4 1 1 0 1 1 1 0 Anion-transporting ATPase DUF2870 PF11069.8 OWF37650.1 - 4e-40 136.1 4.6 8.9e-40 135.0 4.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Gal_Lectin PF02140.18 OWF37651.1 - 6.4e-37 125.9 16.3 2e-18 66.6 5.2 3.1 2 1 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.6 OWF37651.1 - 8.1e-07 28.8 0.0 8.1e-07 28.8 0.0 2.1 2 1 1 3 3 3 1 FAM176 family DUF2407_C PF13373.6 OWF37651.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF3395 PF11875.8 OWF37651.1 - 1.2 9.0 3.2 10 6.0 0.2 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF3395) Rep_fac-A_C PF08646.10 OWF37652.1 - 3.1e-54 182.7 6.2 9.3e-53 177.9 3.0 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OWF37652.1 - 2.9e-33 113.7 0.5 6e-33 112.7 0.5 1.6 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 OWF37652.1 - 1.1e-25 89.5 0.1 2.3e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OWF37652.1 - 1.6e-10 40.8 1.2 3e-10 40.0 0.1 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 OWF37652.1 - 0.0011 19.2 0.1 0.0036 17.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF223 CompInhib_SCIN PF11546.8 OWF37652.1 - 0.031 14.3 0.7 0.064 13.3 0.0 1.9 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN IBR PF01485.21 OWF37652.1 - 0.099 12.9 2.7 0.27 11.5 2.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain GSH-S_ATP PF02955.16 OWF37652.1 - 0.14 11.6 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain zf-AN1 PF01428.16 OWF37652.1 - 0.72 10.1 2.9 1.4 9.2 2.9 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger DUSP PF06337.12 OWF37653.1 - 5.8e-14 52.5 0.7 1.5e-13 51.2 0.1 2.1 2 0 0 2 2 2 1 DUSP domain zf-RING_UBOX PF13445.6 OWF37653.1 - 6.8e-12 45.2 9.3 6.8e-12 45.2 9.3 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF37653.1 - 4.1e-10 39.6 10.0 4.1e-10 39.6 10.0 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 OWF37653.1 - 6.8e-08 32.5 7.9 6.8e-08 32.5 7.9 3.7 3 1 1 4 4 4 1 B-box zinc finger zf-C3HC4 PF00097.25 OWF37653.1 - 8.4e-08 32.0 10.9 8.4e-08 32.0 10.9 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF37653.1 - 6.3e-07 29.6 10.4 6.3e-07 29.6 10.4 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF37653.1 - 8.9e-06 25.4 11.4 8.9e-06 25.4 11.4 3.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF37653.1 - 4.9e-05 23.1 10.5 4.9e-05 23.1 10.5 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF37653.1 - 0.0012 18.8 13.3 0.0012 18.8 13.3 3.2 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 OWF37653.1 - 0.0017 18.5 0.0 0.0081 16.3 0.0 2.2 1 0 0 1 1 1 1 U-box domain ABC_tran_CTD PF16326.5 OWF37653.1 - 0.0024 18.1 0.8 0.0074 16.5 0.8 1.8 1 0 0 1 1 1 1 ABC transporter C-terminal domain ApoLp-III PF07464.11 OWF37653.1 - 0.072 13.2 4.1 0.16 12.1 4.1 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) zf-Nse PF11789.8 OWF37653.1 - 0.095 12.5 5.9 0.35 10.7 5.9 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2408 PF10303.9 OWF37653.1 - 0.17 12.4 3.2 0.15 12.6 0.8 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) DASH_Dad2 PF08654.10 OWF37653.1 - 0.54 10.7 3.3 0.55 10.7 1.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 Exonuc_VII_L PF02601.15 OWF37653.1 - 3.2 7.3 5.2 5.8 6.4 5.2 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_UBOX PF13445.6 OWF37654.1 - 7.4e-13 48.3 9.6 7.4e-13 48.3 9.6 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF37654.1 - 2.6e-11 43.5 8.4 2.6e-11 43.5 8.4 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF37654.1 - 8.8e-09 35.1 11.4 8.8e-09 35.1 11.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF37654.1 - 5.3e-08 33.1 10.4 5.3e-08 33.1 10.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF37654.1 - 5.4e-07 29.4 15.8 1.6e-06 27.8 12.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF37654.1 - 1.1e-05 25.2 11.2 1.1e-05 25.2 11.2 2.5 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF37654.1 - 5.3e-05 23.1 12.6 5.3e-05 23.1 12.6 2.5 2 2 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 OWF37654.1 - 0.00051 20.2 0.1 0.00068 19.8 0.1 1.3 1 1 0 1 1 1 1 U-box domain zf-B_box PF00643.24 OWF37654.1 - 0.002 18.2 0.2 0.002 18.2 0.2 3.7 3 1 1 4 4 4 1 B-box zinc finger zf-4CXXC_R1 PF10497.9 OWF37654.1 - 0.006 16.8 5.4 0.006 16.8 5.4 2.5 1 1 2 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_4 PF14570.6 OWF37654.1 - 0.014 15.2 4.7 0.014 15.2 4.7 2.6 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OWF37654.1 - 0.024 14.8 15.5 0.087 13.0 10.4 2.6 2 1 0 2 2 2 0 zinc RING finger of MSL2 DpnI PF06044.12 OWF37654.1 - 0.033 13.8 1.1 0.033 13.8 1.1 1.9 3 0 0 3 3 3 0 Dam-replacing family zf-Nse PF11789.8 OWF37654.1 - 0.036 13.9 7.4 0.07 13.0 7.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Trm112p PF03966.16 OWF37654.1 - 1.6 9.4 5.5 8.4 7.1 2.6 2.8 2 1 0 2 2 2 0 Trm112p-like protein zf-RING_6 PF14835.6 OWF37654.1 - 2.8 7.9 11.1 0.25 11.2 5.6 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OWF37654.1 - 3.4 7.8 12.8 1.4 9.1 8.8 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUSP PF06337.12 OWF37655.1 - 1.1e-14 54.8 0.2 1.1e-14 54.8 0.2 2.1 2 1 0 2 2 2 1 DUSP domain DUF2408 PF10303.9 OWF37655.1 - 0.041 14.4 1.4 0.1 13.2 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ASD2 PF08687.11 OWF37655.1 - 0.21 11.1 8.5 0.35 10.4 1.3 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Occludin_ELL PF07303.13 OWF37655.1 - 0.63 10.8 0.1 0.63 10.8 0.1 2.8 2 1 0 3 3 3 0 Occludin homology domain zf-RING_UBOX PF13445.6 OWF37657.1 - 6.1e-11 42.2 9.3 2.2e-10 40.4 9.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF37657.1 - 5.7e-09 35.7 11.0 5.7e-09 35.7 11.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF37657.1 - 7.5e-09 35.6 8.0 7.5e-09 35.6 8.0 3.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF37657.1 - 1.7e-08 34.1 6.3 1.7e-08 34.1 6.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF37657.1 - 3.9e-07 30.1 7.4 3.9e-07 30.1 7.4 3.1 4 0 0 4 4 3 1 B-box zinc finger zf-RING_2 PF13639.6 OWF37657.1 - 2.3e-06 27.8 10.9 2.3e-06 27.8 10.9 2.5 2 0 0 2 2 2 1 Ring finger domain Apolipoprotein PF01442.18 OWF37657.1 - 0.0001 22.2 5.5 0.00018 21.5 5.5 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain zf-C3HC4_3 PF13920.6 OWF37657.1 - 0.00017 21.4 10.0 0.00017 21.4 10.0 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF37657.1 - 0.00021 21.2 10.1 0.00021 21.2 10.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 OWF37657.1 - 0.00091 19.4 0.1 0.0024 18.0 0.0 1.7 2 0 0 2 2 1 1 U-box domain zf-UBR PF02207.20 OWF37657.1 - 0.0028 17.8 5.3 0.0028 17.8 5.3 2.6 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Muted PF14942.6 OWF37657.1 - 0.003 17.9 10.4 0.003 17.9 10.4 1.7 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein zf-RING_6 PF14835.6 OWF37657.1 - 0.0038 17.1 1.9 0.0038 17.1 1.9 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OWF37657.1 - 0.008 16.3 5.4 0.008 16.3 5.4 3.2 3 0 0 3 3 3 1 zinc RING finger of MSL2 DUF948 PF06103.11 OWF37657.1 - 0.027 14.7 2.6 0.16 12.3 2.5 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SF-assemblin PF06705.11 OWF37657.1 - 0.04 13.3 9.9 0.053 12.9 9.7 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin Jnk-SapK_ap_N PF09744.9 OWF37657.1 - 0.083 13.1 13.6 0.035 14.3 11.3 1.5 2 0 0 2 2 1 0 JNK_SAPK-associated protein-1 YtxH PF12732.7 OWF37657.1 - 0.16 12.5 1.3 6 7.5 1.0 2.4 1 1 1 2 2 2 0 YtxH-like protein Exonuc_VII_L PF02601.15 OWF37657.1 - 0.22 11.1 6.5 0.32 10.5 6.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-Nse PF11789.8 OWF37657.1 - 0.22 11.4 5.8 0.28 11.0 4.6 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Snapin_Pallidin PF14712.6 OWF37657.1 - 0.22 12.0 10.4 2.3 8.7 0.6 2.7 1 1 1 2 2 2 0 Snapin/Pallidin HTH_Tnp_Tc3_1 PF11427.8 OWF37657.1 - 0.89 9.4 3.6 5.1 7.0 0.1 3.0 3 0 0 3 3 3 0 Tc3 transposase NPV_P10 PF05531.12 OWF37657.1 - 0.94 10.0 10.0 2.9 8.4 0.4 3.1 2 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 OWF37657.1 - 1.3 9.5 7.7 3.6 8.0 7.6 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) IBR PF01485.21 OWF37657.1 - 2 8.7 17.9 0.16 12.2 2.8 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DUF2203 PF09969.9 OWF37657.1 - 2.1 9.1 5.6 6.7 7.5 3.7 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Baculo_PEP_C PF04513.12 OWF37657.1 - 2.8 8.0 7.1 4.2 7.4 4.9 2.2 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 OWF37657.1 - 4.4 8.0 13.7 0.77 10.4 7.1 2.6 2 2 0 2 2 2 0 Initiation control protein YabA DUF2205 PF10224.9 OWF37657.1 - 7.3 6.7 12.1 0.16 12.0 1.2 3.2 2 1 2 4 4 4 0 Short coiled-coil protein DUF1664 PF07889.12 OWF37657.1 - 9.4 6.3 8.2 9.7 6.3 4.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L19 PF01245.20 OWF37658.1 - 6.5e-16 58.2 0.1 1.7e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L19 Pkinase PF00069.25 OWF37659.1 - 1.1e-35 123.3 0.1 1.7e-35 122.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37659.1 - 3.6e-18 65.8 0.0 6.8e-18 64.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF37659.1 - 0.00019 20.4 0.4 0.00019 20.4 0.4 2.2 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OWF37659.1 - 0.00025 20.5 1.0 0.0024 17.2 0.2 2.5 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OWF37659.1 - 0.084 11.8 1.1 0.18 10.7 1.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L1 PF00687.21 OWF37660.1 - 5.5e-43 147.1 2.5 6.5e-43 146.9 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 OWF37660.1 - 0.039 14.0 1.3 0.07 13.2 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function UCH PF00443.29 OWF37661.1 - 3.4e-48 164.4 4.1 3.8e-48 164.2 2.5 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF37661.1 - 2.5e-38 132.5 1.8 6.6e-38 131.1 1.8 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 OWF37661.1 - 0.00039 20.8 2.0 0.49 10.9 0.0 3.8 4 0 0 4 4 4 2 Ubiquitin-like domain Dynamin_M PF01031.20 OWF37661.1 - 0.028 13.6 0.1 0.067 12.4 0.1 1.6 1 0 0 1 1 1 0 Dynamin central region SMYLE_N PF18615.1 OWF37661.1 - 6.6 6.2 10.1 9.1 5.7 5.0 2.7 2 1 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PBP1_TM PF14812.6 OWF37662.1 - 0.044 14.2 0.2 0.044 14.2 0.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3290 PF11694.8 OWF37662.1 - 1.9 8.5 5.1 1.7 8.6 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) zf-H2C2_2 PF13465.6 OWF37663.1 - 0.00072 19.9 1.6 0.0072 16.7 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain Zn-C2H2_12 PF18112.1 OWF37663.1 - 0.0039 17.6 0.7 1.2 9.7 0.1 2.8 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain SAP PF02037.27 OWF37663.1 - 0.16 11.7 0.7 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 SAP domain zf-C2H2_4 PF13894.6 OWF37663.1 - 0.23 12.4 0.3 0.23 12.4 0.3 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF37663.1 - 0.47 11.0 17.5 0.52 10.9 0.2 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type CDC13_N PF16853.5 OWF37664.1 - 0.82 9.2 9.6 2.2 7.8 9.6 1.7 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus Exonuc_VII_L PF02601.15 OWF37664.1 - 4.9 6.6 16.7 0.24 10.9 6.7 2.7 3 0 0 3 3 3 0 Exonuclease VII, large subunit Snf7 PF03357.21 OWF37665.1 - 6e-45 152.9 31.8 6e-45 152.9 31.8 1.4 2 0 0 2 2 2 1 Snf7 CSD PF00313.22 OWF37666.1 - 4.8e-71 234.5 20.6 2.4e-16 59.3 0.3 9.3 9 0 0 9 9 9 5 'Cold-shock' DNA-binding domain S1-like PF14444.6 OWF37666.1 - 7.1e-12 45.1 7.7 0.015 15.2 0.2 6.5 6 0 0 6 6 6 4 S1-like SUZ-C PF12901.7 OWF37666.1 - 2.5e-06 27.4 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 SUZ-C motif DUF11 PF01345.18 OWF37666.1 - 0.069 13.4 1.0 17 5.8 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function DUF11 HHA PF05321.11 OWF37666.1 - 0.26 11.6 0.5 4.6 7.6 0.0 3.2 4 0 0 4 4 4 0 Haemolysin expression modulating protein Methyltransf_25 PF13649.6 OWF37667.1 - 2.6e-11 44.1 0.1 9.6e-11 42.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF37667.1 - 8.1e-10 38.7 0.1 1.8e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF37667.1 - 6.4e-09 36.3 0.0 2.3e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OWF37667.1 - 1.5e-08 34.4 0.4 1.5e-08 34.4 0.4 1.9 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 OWF37667.1 - 2.9e-07 29.7 0.1 4.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 OWF37667.1 - 4.6e-07 29.5 0.1 8.4e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OWF37667.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF37667.1 - 1.9e-05 24.1 0.1 3.2e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OWF37667.1 - 0.00024 21.8 0.0 0.00052 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CC2-LZ PF16516.5 OWF37667.1 - 0.00064 20.0 1.3 0.0018 18.6 1.3 1.7 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PRMT5 PF05185.16 OWF37667.1 - 0.00068 19.5 0.5 0.0018 18.1 0.3 1.8 1 1 1 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 OWF37667.1 - 0.0013 18.7 0.0 0.004 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OWF37667.1 - 0.0013 18.1 0.1 0.0069 15.7 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain TehB PF03848.14 OWF37667.1 - 0.0021 17.5 2.4 0.0071 15.8 0.1 2.5 2 1 1 3 3 3 1 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 OWF37667.1 - 0.005 16.5 0.2 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 OWF37667.1 - 0.0063 17.5 0.0 0.018 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain WEMBL PF05701.11 OWF37667.1 - 0.0064 15.3 0.3 0.0097 14.6 0.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light zf-C2H2_2 PF12756.7 OWF37667.1 - 0.0075 16.6 2.5 0.013 15.8 0.2 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PIN_9 PF18477.1 OWF37667.1 - 0.0085 16.4 0.3 0.039 14.3 0.0 2.1 2 0 0 2 2 2 1 PIN like domain PCMT PF01135.19 OWF37667.1 - 0.0091 15.8 0.1 0.0091 15.8 0.1 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OWF37667.1 - 0.042 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 OWF37667.1 - 0.099 12.1 0.3 8.1 5.9 0.0 2.6 2 0 0 2 2 2 0 Putative methyltransferase XhlA PF10779.9 OWF37667.1 - 0.67 10.2 3.3 0.54 10.5 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA LPP PF04728.13 OWF37668.1 - 4.8e-06 26.9 1.8 4.9 7.6 0.0 4.5 2 1 4 6 6 6 1 Lipoprotein leucine-zipper CLZ PF16526.5 OWF37668.1 - 0.0004 20.7 7.5 9.7 6.6 0.9 4.1 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 OWF37668.1 - 0.00057 20.1 16.9 0.034 14.4 4.9 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 OWF37668.1 - 0.00076 19.6 0.3 0.028 14.5 0.1 2.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 OWF37668.1 - 0.0009 19.5 3.3 0.033 14.5 0.2 3.1 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 phiKZ_IP PF12699.7 OWF37668.1 - 0.0034 16.6 0.6 1.5 7.9 0.1 2.3 1 1 1 2 2 2 2 phiKZ-like phage internal head proteins FlaC_arch PF05377.11 OWF37668.1 - 0.0036 17.7 11.8 1.4 9.4 0.6 3.3 1 1 2 3 3 3 2 Flagella accessory protein C (FlaC) Ran-binding PF05508.11 OWF37668.1 - 0.0042 16.1 4.1 0.0052 15.8 4.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein DUF16 PF01519.16 OWF37668.1 - 0.011 16.2 0.0 0.45 11.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 COG5 PF10392.9 OWF37668.1 - 0.013 15.7 10.7 0.36 11.0 4.9 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF4618 PF15397.6 OWF37668.1 - 0.013 14.9 5.1 0.5 9.8 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) MbeD_MobD PF04899.12 OWF37668.1 - 0.019 15.1 7.5 9 6.5 0.1 4.0 1 1 3 4 4 4 0 MbeD/MobD like DUF1664 PF07889.12 OWF37668.1 - 0.021 14.9 3.8 1.5 8.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YhfT PF10797.9 OWF37668.1 - 0.028 13.5 7.5 0.039 13.0 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function JIP_LZII PF16471.5 OWF37668.1 - 0.046 13.9 5.2 1.5 9.0 0.6 2.8 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DASH_Dad4 PF08650.10 OWF37668.1 - 0.057 13.4 12.1 0.94 9.5 0.5 3.7 1 1 3 4 4 4 0 DASH complex subunit Dad4 ATG16 PF08614.11 OWF37668.1 - 0.063 13.5 0.2 0.089 13.0 0.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 OWF37668.1 - 0.11 12.7 5.4 0.16 12.2 1.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CREPT PF16566.5 OWF37668.1 - 0.12 12.6 0.9 0.34 11.1 0.5 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CENP-F_leu_zip PF10473.9 OWF37668.1 - 0.16 12.0 1.3 0.95 9.5 0.8 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2730 PF10805.8 OWF37668.1 - 0.16 12.0 5.4 0.34 11.0 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) PspA_IM30 PF04012.12 OWF37668.1 - 0.25 10.9 0.0 3.8 7.0 0.0 2.1 1 1 1 2 2 2 0 PspA/IM30 family Laminin_II PF06009.12 OWF37668.1 - 0.41 10.7 5.2 3.6 7.6 5.2 2.0 1 1 0 1 1 1 0 Laminin Domain II YlbE PF14003.6 OWF37668.1 - 1.6 9.2 10.5 3.9 8.0 0.4 3.6 2 2 2 4 4 4 0 YlbE-like protein DASH_Spc19 PF08287.11 OWF37668.1 - 2.2 8.2 20.4 9.2 6.1 12.5 3.1 1 1 1 2 2 2 0 Spc19 Phage_tail_T PF06223.12 OWF37668.1 - 3.4 8.2 5.6 39 4.8 0.2 2.9 1 1 1 2 2 2 0 Minor tail protein T C2 PF00168.30 OWF37669.1 - 3.2e-43 146.2 0.1 4.5e-20 71.9 0.0 3.7 3 0 0 3 3 3 2 C2 domain FYVE_2 PF02318.16 OWF37669.1 - 7.6e-19 68.1 6.3 1.5e-18 67.1 6.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Dehyd-heme_bind PF09098.10 OWF37669.1 - 0.044 13.4 0.3 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding zf-piccolo PF05715.13 OWF37669.1 - 0.41 10.8 9.5 0.87 9.8 9.5 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4_3 PF13920.6 OWF37669.1 - 1.1 9.1 8.9 2 8.3 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_LYR PF05347.15 OWF37670.1 - 1.8e-14 53.5 0.1 3e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OWF37670.1 - 5.9e-05 23.7 0.0 8.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF2004 PF09406.10 OWF37670.1 - 0.049 14.0 0.2 0.064 13.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2004) Complex1_LYR_1 PF13232.6 OWF37670.1 - 0.076 13.6 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Astacin PF01400.24 OWF37671.1 - 2e-60 203.7 0.0 3e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kringle PF00051.18 OWF37671.1 - 6.1e-19 68.1 6.4 6.9e-19 67.9 4.1 2.4 2 0 0 2 2 2 1 Kringle domain Lectin_C PF00059.21 OWF37671.1 - 2.4e-07 31.4 0.1 7.9e-07 29.8 0.1 2.0 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF37671.1 - 0.0005 19.8 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like MALT1_Ig PF18703.1 OWF37674.1 - 2.9e-05 24.1 0.2 3.4e-05 23.9 0.2 1.1 1 0 0 1 1 1 1 MALT1 Ig-like domain MAM1 PF10434.9 OWF37674.1 - 0.027 14.1 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 Monopolin complex protein MAM1 Peptidase_M15_3 PF08291.11 OWF37674.1 - 0.17 12.0 0.1 0.25 11.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M15 dCache_1 PF02743.18 OWF37676.1 - 8e-18 65.1 1.0 2.7e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 Cache domain VWA_N PF08399.11 OWF37676.1 - 2.7e-07 31.1 1.3 8.6e-07 29.5 0.3 2.3 2 0 0 2 2 2 1 VWA N-terminal VWA_2 PF13519.6 OWF37676.1 - 6.8e-05 23.5 0.2 0.00022 21.8 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OWF37676.1 - 0.0036 17.6 0.5 0.0078 16.5 0.5 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Fer2 PF00111.27 OWF37677.1 - 1.7e-08 34.3 0.1 2.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ISP3_C PF18045.1 OWF37677.1 - 0.099 12.5 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 ISP3 C-terminal GATA PF00320.27 OWF37678.1 - 2e-14 52.9 1.9 2e-14 52.9 1.9 3.4 4 0 0 4 4 4 1 GATA zinc finger NOB1_Zn_bind PF08772.11 OWF37678.1 - 0.017 15.3 2.6 0.017 15.3 2.6 3.9 3 1 2 5 5 5 0 Nin one binding (NOB1) Zn-ribbon like Auto_anti-p27 PF06677.12 OWF37678.1 - 0.17 12.0 0.3 0.17 12.0 0.3 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 OWF37678.1 - 0.61 10.3 12.1 1.8 8.7 1.0 3.6 3 1 1 4 4 4 0 Zinc ribbon domain DUF3039 PF11238.8 OWF37678.1 - 0.89 9.4 7.6 0.98 9.2 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zinc-ribbons_6 PF07191.12 OWF37678.1 - 1.3 9.1 10.0 3.1 7.8 7.7 2.8 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 OWF37678.1 - 2.1 8.5 18.5 16 5.6 14.9 3.5 2 1 0 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 OWF37678.1 - 2.7 7.5 8.6 2.2 7.7 0.8 2.7 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C3H2C3 PF17122.5 OWF37678.1 - 9.2 6.4 12.9 4.2 7.5 2.6 4.0 3 2 1 4 4 4 0 Zinc-finger Adap_comp_sub PF00928.21 OWF37679.1 - 1.5e-91 306.4 0.4 2.3e-91 305.8 0.1 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OWF37679.1 - 1.2e-09 38.2 2.7 2.2e-09 37.4 2.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 OWF37679.1 - 0.0012 18.8 0.1 0.0036 17.3 0.1 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain UQ_con PF00179.26 OWF37680.1 - 1.4e-33 115.5 0.1 2.3e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase_Tyr PF07714.17 OWF37682.1 - 1.2e-98 329.5 0.0 1.6e-98 329.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF37682.1 - 2e-45 155.2 0.0 3.2e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 OWF37682.1 - 5e-18 65.2 7.7 2e-17 63.2 7.7 2.2 1 0 0 1 1 1 1 Kringle domain I-set PF07679.16 OWF37682.1 - 3.2e-13 49.5 0.0 6.3e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF37682.1 - 5.2e-12 46.2 0.0 1.7e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 OWF37682.1 - 1.3e-09 38.6 5.3 4.6e-09 36.9 5.3 1.9 1 0 0 1 1 1 1 Fz domain Ig_2 PF13895.6 OWF37682.1 - 3.6e-08 33.6 0.0 8.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 OWF37682.1 - 6.5e-05 23.0 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Haspin_kinase PF12330.8 OWF37682.1 - 0.0022 17.0 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain V-set PF07686.17 OWF37682.1 - 0.011 16.0 0.0 0.22 11.7 0.0 2.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF37682.1 - 0.026 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Mucin2_WxxW PF13330.6 OWF37682.1 - 0.11 13.4 0.7 0.47 11.3 0.7 2.2 1 0 0 1 1 1 0 Mucin-2 protein WxxW repeating region RRP7 PF12923.7 OWF37682.1 - 0.15 12.2 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Spiralin PF05215.13 OWF37683.1 - 0.02 14.3 0.1 0.065 12.6 0.0 1.8 2 0 0 2 2 2 0 Spiralin An_peroxidase PF03098.15 OWF37684.1 - 7.5e-194 645.2 0.0 1.1e-193 644.7 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 OWF37684.1 - 1e-26 92.8 0.0 4.1e-17 62.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF37684.1 - 1.4e-20 73.6 0.0 2.8e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain LRR_8 PF13855.6 OWF37684.1 - 4.4e-16 58.4 6.7 5.5e-12 45.3 6.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat Ig_2 PF13895.6 OWF37684.1 - 1.7e-14 53.9 0.0 1.5e-07 31.6 0.0 2.6 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 OWF37684.1 - 1.2e-09 38.2 0.0 3.8e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain LRR_4 PF12799.7 OWF37684.1 - 4e-08 33.4 7.0 0.0018 18.6 0.3 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) VWC PF00093.18 OWF37684.1 - 1.5e-06 28.4 17.6 1.5e-06 28.4 17.6 3.9 4 0 0 4 4 4 1 von Willebrand factor type C domain LRR_9 PF14580.6 OWF37684.1 - 9.9e-06 25.2 0.5 2e-05 24.2 0.5 1.4 1 0 0 1 1 1 1 Leucine-rich repeat V-set PF07686.17 OWF37684.1 - 0.00018 21.6 0.1 0.15 12.3 0.1 3.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_5 PF13306.6 OWF37684.1 - 0.00063 19.7 1.3 0.0036 17.2 0.0 2.6 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) Ig_6 PF18452.1 OWF37684.1 - 0.012 15.2 0.0 0.6 9.7 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin domain IL10 PF00726.17 OWF37684.1 - 0.13 11.7 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Interleukin 10 TILa PF12714.7 OWF37684.1 - 1.7 8.7 22.1 0.22 11.5 12.9 2.8 2 0 0 2 2 2 0 TILa domain Amnionless PF14828.6 OWF37684.1 - 2.4 6.9 11.1 3.9 6.2 11.1 1.3 1 0 0 1 1 1 0 Amnionless Mis14 PF08641.12 OWF37685.1 - 0.0044 17.3 0.0 0.0067 16.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Laminin_G_2 PF02210.24 OWF37686.1 - 4.3e-74 247.1 14.1 5.2e-16 59.4 0.4 6.5 6 0 0 6 6 6 6 Laminin G domain Laminin_G_1 PF00054.23 OWF37686.1 - 2.1e-49 167.1 2.9 8.4e-13 48.7 0.0 7.0 6 1 0 6 6 6 6 Laminin G domain EGF PF00008.27 OWF37686.1 - 1.7e-07 31.4 58.2 2.4e-05 24.5 4.2 5.4 5 0 0 5 5 5 3 EGF-like domain Laminin_G_3 PF13385.6 OWF37686.1 - 4.2e-06 27.0 9.9 0.75 9.9 0.1 6.2 7 0 0 7 7 7 2 Concanavalin A-like lectin/glucanases superfamily Glycophorin_A PF01102.18 OWF37686.1 - 0.0029 17.8 0.1 0.0077 16.5 0.1 1.7 1 0 0 1 1 1 1 Glycophorin A hEGF PF12661.7 OWF37686.1 - 0.009 16.6 4.4 0.009 16.6 4.4 5.5 4 0 0 4 4 4 1 Human growth factor-like EGF RIFIN PF02009.16 OWF37686.1 - 0.031 14.2 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 OWF37686.1 - 0.073 13.0 0.1 0.073 13.0 0.1 1.8 2 0 0 2 2 2 0 TMEM154 protein family DUF2207 PF09972.9 OWF37686.1 - 0.1 11.3 0.4 0.67 8.6 0.0 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 OWF37686.1 - 0.41 10.6 1.3 0.86 9.6 1.3 1.4 1 0 0 1 1 1 0 Syndecan domain CBM_5_12 PF02839.14 OWF37687.1 - 0.015 15.8 0.0 4.8e+03 -1.5 0.0 8.6 16 0 0 16 16 16 0 Carbohydrate binding domain GH-E PF14410.6 OWF37688.1 - 1.2e-07 32.0 14.4 20 5.7 0.1 7.0 2 1 5 7 7 7 7 HNH/ENDO VII superfamily nuclease with conserved GHE residues GFA PF04828.14 OWF37688.1 - 0.00077 19.7 4.2 15 6.0 0.2 5.7 1 1 4 5 5 5 1 Glutathione-dependent formaldehyde-activating enzyme C2 PF00168.30 OWF37689.1 - 3.7e-78 258.4 0.9 8.6e-19 67.7 0.1 8.1 7 1 0 7 7 7 7 C2 domain FerB PF08150.12 OWF37689.1 - 2.1e-31 108.3 0.1 2.1e-31 108.3 0.1 2.8 3 0 0 3 3 3 1 FerB (NUC096) domain Ferlin_C PF16165.5 OWF37689.1 - 4.1e-31 108.0 15.9 4.1e-28 98.3 0.0 4.2 3 1 1 4 4 4 2 Ferlin C-terminus FerI PF08151.12 OWF37689.1 - 3.1e-19 68.8 2.7 1.1e-18 67.0 2.7 2.1 1 0 0 1 1 1 1 FerI (NUC094) domain MDFI PF15316.6 OWF37689.1 - 0.86 9.7 4.5 3 7.9 4.5 2.0 1 0 0 1 1 1 0 MyoD family inhibitor Hydrolase PF00702.26 OWF37690.1 - 7.5e-06 26.4 0.0 1.1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Herpes_TK_C PF08465.10 OWF37691.1 - 2.7e-05 23.8 19.6 72 3.2 0.0 8.9 1 1 15 16 16 16 0 Thymidine kinase from Herpesvirus C-terminal DUF3215 PF11503.8 OWF37691.1 - 0.00014 21.6 20.1 22 5.0 0.1 6.7 1 1 14 15 15 15 13 Protein of unknown function (DUF3215) PrgU PF09627.10 OWF37691.1 - 0.24 11.4 17.3 4.6 7.3 2.2 3.3 1 1 2 3 3 3 0 PrgU-like protein Tox-HDC PF15656.6 OWF37691.1 - 2.8 8.2 32.5 28 4.9 2.6 5.1 1 1 3 4 4 4 0 Toxin with a H, D/N and C signature MRP-S32 PF10210.9 OWF37692.1 - 0.0014 19.1 1.9 0.87 10.2 0.3 3.0 1 1 1 3 3 3 2 Mitochondrial 28S ribosomal protein S32 RHH_3 PF12651.7 OWF37692.1 - 0.2 11.7 1.1 35 4.5 0.0 3.9 5 1 0 5 5 5 0 Ribbon-helix-helix domain MFS_1 PF07690.16 OWF37693.1 - 3.9e-40 137.8 33.2 3.5e-37 128.2 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37693.1 - 7e-07 28.5 13.1 7e-07 28.5 13.1 3.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF37694.1 - 6.3e-40 137.2 33.9 2.6e-37 128.6 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37694.1 - 2.8e-10 39.7 32.5 1.2e-09 37.6 11.1 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 OWF37695.1 - 7.9e-39 133.6 44.6 5.3e-36 124.3 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37695.1 - 1.9e-08 33.6 21.3 1.5e-07 30.7 15.3 3.5 2 2 1 3 3 3 2 Sugar (and other) transporter DUF4231 PF14015.6 OWF37695.1 - 6.6 7.3 7.3 56 4.3 0.5 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 OWF37696.1 - 4.6e-48 163.9 32.0 2.3e-45 155.1 27.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37696.1 - 6.6e-07 28.5 27.7 8.6e-05 21.6 26.2 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3926 PF13080.6 OWF37696.1 - 0.17 11.8 1.3 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) DUF4781 PF16013.5 OWF37696.1 - 5.5 5.7 7.5 0.21 10.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) MFS_1 PF07690.16 OWF37697.1 - 4.8e-50 170.5 30.1 1.9e-47 161.9 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37697.1 - 4.4e-07 29.1 26.1 2.4e-06 26.7 8.0 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter zf-B_box PF00643.24 OWF37700.1 - 3.2e-05 24.0 2.8 0.00011 22.2 2.8 2.0 1 0 0 1 1 1 1 B-box zinc finger NHL PF01436.21 OWF37700.1 - 0.00013 21.8 6.3 0.035 14.2 0.1 3.9 4 0 0 4 4 4 2 NHL repeat zf-UBR PF02207.20 OWF37700.1 - 0.016 15.3 1.1 0.016 15.3 1.1 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF4127 PF13552.6 OWF37700.1 - 0.17 10.5 0.3 0.24 10.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) AA_permease PF00324.21 OWF37701.1 - 7.8e-30 103.9 26.5 7.8e-30 103.9 26.5 2.3 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 OWF37701.1 - 1.3e-28 100.0 25.4 1.3e-28 100.0 25.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 OWF37701.1 - 1.6e-15 56.9 7.8 1.6e-15 56.9 7.8 2.7 2 0 0 2 2 2 1 C-terminus of AA_permease ASH PF15780.5 OWF37702.1 - 0.041 14.1 0.0 0.56 10.5 0.0 2.8 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PIG-P PF08510.12 OWF37703.1 - 1e-32 112.6 2.1 1.2e-32 112.4 2.1 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 OWF37703.1 - 0.0014 18.9 8.5 0.0025 18.1 8.5 1.4 1 1 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Phage_holin_3_6 PF07332.11 OWF37703.1 - 0.16 12.0 0.7 0.21 11.6 0.7 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Adeno_52K PF03052.15 OWF37704.1 - 0.079 12.4 0.4 0.16 11.4 0.4 1.4 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa Collectrin PF16959.5 OWF37704.1 - 0.15 11.8 1.6 2 8.2 0.1 2.7 3 0 0 3 3 3 0 Renal amino acid transporter zf-B_box PF00643.24 OWF37705.1 - 7.2e-08 32.5 26.2 1.3e-07 31.7 6.8 4.0 4 1 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 OWF37705.1 - 5.7e-07 29.8 10.4 5.7e-07 29.8 10.4 3.6 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF37705.1 - 1.1e-06 28.5 7.5 1.1e-06 28.5 7.5 4.1 3 3 1 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OWF37705.1 - 0.00022 21.0 2.4 0.00022 21.0 2.4 4.7 3 2 1 4 4 4 2 Prokaryotic RING finger family 4 Trm112p PF03966.16 OWF37705.1 - 0.072 13.7 5.3 1.1 9.9 5.3 2.4 1 1 0 1 1 1 0 Trm112p-like protein IBR PF01485.21 OWF37705.1 - 2.4 8.4 36.3 6.2 7.1 9.0 4.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain FYVE PF01363.21 OWF37705.1 - 7.9 6.7 37.6 0.35 11.0 4.2 3.4 2 1 1 3 3 3 0 FYVE zinc finger zf-B_box PF00643.24 OWF37706.1 - 3.4e-10 39.9 23.7 9.7e-08 32.1 7.5 4.3 5 0 0 5 5 5 2 B-box zinc finger zf-RING_2 PF13639.6 OWF37706.1 - 1.9e-07 31.3 10.6 1.9e-07 31.3 10.6 3.7 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF37706.1 - 6.3e-07 29.3 9.3 6.3e-07 29.3 9.3 3.9 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF37706.1 - 1.5e-05 24.8 11.3 1.5e-05 24.8 11.3 4.2 3 2 0 3 3 3 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF37706.1 - 0.0004 20.2 8.0 0.0004 20.2 8.0 4.0 3 2 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OWF37706.1 - 0.01 15.6 12.3 0.01 15.6 12.3 4.3 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Ku_PK_bind PF08785.11 OWF37706.1 - 0.026 14.7 0.1 0.041 14.0 0.1 1.2 1 0 0 1 1 1 0 Ku C terminal domain like FYVE PF01363.21 OWF37706.1 - 0.25 11.5 34.1 0.58 10.3 9.7 3.4 2 1 1 3 3 3 0 FYVE zinc finger 7tm_1 PF00001.21 OWF37707.1 - 5.4e-28 98.0 15.1 1.2e-25 90.3 15.1 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 OWF37707.1 - 0.011 15.5 9.3 0.011 15.5 9.3 2.8 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 Plasmodium_Vir PF05795.11 OWF37707.1 - 0.057 12.8 0.0 0.91 8.9 0.0 2.1 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 OWF37707.1 - 0.8 10.7 4.1 6.6 7.8 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) Scramblase PF03803.15 OWF37708.1 - 5.9e-48 163.1 0.0 7e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Scramblase Podoplanin PF05808.11 OWF37710.1 - 1e-12 48.5 72.3 9.4 6.3 0.5 16.3 1 1 13 14 14 14 13 Podoplanin Lipocalin_7 PF14651.6 OWF37710.1 - 0.0013 18.6 116.9 2.8 7.9 3.2 16.4 1 1 8 9 9 9 4 Lipocalin / cytosolic fatty-acid binding protein family fn3 PF00041.21 OWF37711.1 - 1e-06 29.0 0.1 2e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain GPR15L PF15854.5 OWF37711.1 - 0.004 17.3 0.3 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 G-protein coupled receptor ligand 15 C1q PF00386.21 OWF37712.1 - 1.8e-21 76.7 0.0 3.9e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF37712.1 - 5.3e-05 23.1 0.1 9.7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 BclA C-terminal domain Anti-adapt_IraP PF10796.9 OWF37712.1 - 0.035 14.7 0.6 0.55 10.8 0.0 2.7 2 1 1 3 3 3 0 Sigma-S stabilisation anti-adaptor protein SF-assemblin PF06705.11 OWF37712.1 - 0.076 12.4 6.5 0.11 11.9 6.5 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin PdaC PF13739.6 OWF37712.1 - 0.12 13.3 1.8 1.1 10.3 0.3 2.4 2 0 0 2 2 2 0 Deacetylase PdaC Peptidase_M3_N PF08439.10 OWF37712.1 - 0.14 12.5 0.1 0.63 10.4 0.0 2.0 2 0 0 2 2 2 0 Oligopeptidase F Fib_alpha PF08702.10 OWF37712.1 - 0.46 10.7 8.1 0.44 10.7 3.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 OWF37712.1 - 1.3 9.5 3.7 4.7 7.8 0.7 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein C1q PF00386.21 OWF37713.1 - 8.4e-21 74.5 0.0 9.2e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF37713.1 - 4.3e-05 23.4 0.1 5.5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 BclA C-terminal domain C1q PF00386.21 OWF37714.1 - 2e-19 70.1 0.0 3.7e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF37714.1 - 0.0011 18.9 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 BclA C-terminal domain Anti-adapt_IraP PF10796.9 OWF37714.1 - 0.077 13.6 3.9 1.9 9.1 0.1 3.8 3 2 1 4 4 4 0 Sigma-S stabilisation anti-adaptor protein APC_u9 PF16633.5 OWF37714.1 - 0.12 13.5 0.5 50 5.1 0.0 3.1 2 2 2 4 4 4 0 Unstructured region on APC between 1st two creatine-rich regions NusB PF01029.18 OWF37714.1 - 0.52 10.6 4.6 0.57 10.4 1.8 2.1 1 1 1 2 2 2 0 NusB family DUF4559 PF15112.6 OWF37714.1 - 1.9 8.1 10.5 0.9 9.2 6.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) FXa_inhibition PF14670.6 OWF37715.1 - 1.3e-45 153.4 147.1 6e-11 42.4 7.4 37.5 14 4 13 27 27 27 9 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 OWF37715.1 - 6.2e-34 115.9 637.1 3.1e-05 24.0 10.0 34.2 13 8 20 33 33 33 22 Laminin EGF domain cEGF PF12662.7 OWF37715.1 - 8.1e-19 67.2 50.8 2.2e-08 33.8 1.4 37.8 38 6 3 41 41 41 9 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF37715.1 - 4.1e-18 65.3 84.6 5.6e-07 29.7 6.5 34.4 23 9 8 32 32 32 6 Calcium-binding EGF domain EGF_3 PF12947.7 OWF37715.1 - 0.00046 20.3 12.3 0.00046 20.3 12.3 33.3 32 2 3 35 35 35 5 EGF domain hEGF PF12661.7 OWF37715.1 - 0.003 18.1 37.8 0.0066 17.0 5.8 38.6 34 3 2 36 36 36 22 Human growth factor-like EGF EGF_2 PF07974.13 OWF37715.1 - 0.0057 17.0 13.1 0.0057 17.0 13.1 47.2 35 15 7 42 42 42 11 EGF-like domain BH4 PF02180.17 OWF37715.1 - 0.0069 16.2 0.0 0.028 14.2 0.0 2.2 1 0 0 1 1 1 1 Bcl-2 homology region 4 Aldo_ket_red PF00248.21 OWF37716.1 - 1.1e-64 218.4 0.0 1.6e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HPS3_Mid PF14762.6 OWF37717.1 - 9.9e-69 231.9 0.1 3.2e-68 230.3 0.1 1.7 1 1 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.6 OWF37717.1 - 4.2e-52 176.8 2.1 4.8e-52 176.6 1.1 1.6 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 HPS3_C PF14763.6 OWF37717.1 - 5e-22 78.7 2.5 8.6e-17 61.5 0.4 2.2 2 0 0 2 2 2 2 Hermansky-Pudlak syndrome 3, C-terminal RasGEF_N_2 PF14663.6 OWF37717.1 - 0.077 13.4 0.0 0.27 11.7 0.0 2.0 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain 7tm_1 PF00001.21 OWF37718.1 - 1.4e-23 83.6 3.1 1.9e-23 83.1 3.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4075 PF13294.6 OWF37718.1 - 0.26 11.5 2.4 0.61 10.3 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) HemY_N PF07219.13 OWF37718.1 - 0.31 11.2 1.2 1.1 9.5 1.2 1.9 1 0 0 1 1 1 0 HemY protein N-terminus PEHE PF15275.6 OWF37718.1 - 4.4 7.9 8.1 9.7 6.8 7.8 1.8 1 1 0 1 1 1 0 PEHE domain DUF3421 PF11901.8 OWF37721.1 - 2.3e-15 56.6 0.0 0.22 11.5 0.0 8.1 1 1 4 7 7 7 4 Protein of unknown function (DUF3421) Herpes_U15 PF05613.11 OWF37721.1 - 0.012 16.4 19.0 58 4.4 0.0 8.8 3 2 6 11 11 11 0 Human herpesvirus U15 protein zf-CCCH_7 PF18586.1 OWF37721.1 - 0.012 15.9 12.2 56 4.2 0.0 8.0 2 2 8 10 10 10 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PTSIIB_sorb PF03830.15 OWF37721.1 - 0.26 11.5 3.7 28 4.9 0.0 4.5 1 1 3 5 5 5 0 PTS system sorbose subfamily IIB component Csm1_N PF18504.1 OWF37721.1 - 0.71 10.3 23.9 8.2 6.8 0.0 9.5 6 3 4 11 11 11 0 Csm1 N-terminal domain HSBP1 PF06825.12 OWF37721.1 - 0.97 9.3 12.2 15 5.5 0.1 5.6 7 0 0 7 7 7 0 Heat shock factor binding protein 1 NEMO PF11577.8 OWF37721.1 - 3.3 7.8 52.0 0.64 10.1 2.0 9.9 4 4 5 10 10 10 0 NF-kappa-B essential modulator NEMO TED_complement PF07678.14 OWF37722.1 - 1.7e-90 303.3 0.0 2.4e-90 302.8 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 OWF37722.1 - 6.7e-27 94.0 1.1 2.4e-26 92.3 0.2 2.5 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain A2M PF00207.22 OWF37722.1 - 7.5e-23 80.2 0.0 2.6e-22 78.5 0.0 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 OWF37722.1 - 3.5e-22 79.3 0.1 1e-19 71.3 0.0 3.5 2 2 1 3 3 3 1 Alpha-2-macroglobulin bait region domain MG1 PF17790.1 OWF37722.1 - 2.2e-13 50.5 0.0 8.5e-13 48.6 0.0 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG1 MG3 PF17791.1 OWF37722.1 - 2.1e-12 47.2 0.8 2.4e-11 43.7 0.0 3.3 4 0 0 4 4 4 1 Macroglobulin domain MG3 MG2 PF01835.19 OWF37722.1 - 3.4e-12 46.7 0.2 1.1e-11 45.0 0.2 2.0 1 0 0 1 1 1 1 MG2 domain NTR PF01759.21 OWF37722.1 - 3.7e-09 36.3 0.0 1.1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 UNC-6/NTR/C345C module MG4 PF17789.1 OWF37722.1 - 4.8e-08 33.0 0.1 2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Macroglobulin domain MG4 CxC2 PF18803.1 OWF37722.1 - 0.0079 16.3 0.1 0.024 14.8 0.1 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases SQHop_cyclase_C PF13243.6 OWF37722.1 - 0.017 14.3 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain MBOAT PF03062.19 OWF37723.1 - 1.5e-32 113.4 4.7 1.5e-32 113.4 4.7 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Alk_phosphatase PF00245.20 OWF37724.1 - 9.3e-41 140.1 0.7 1.1e-40 139.8 0.7 1.1 1 0 0 1 1 1 1 Alkaline phosphatase KH_4 PF13083.6 OWF37724.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 KH domain Metalloenzyme PF01676.18 OWF37724.1 - 0.2 11.0 0.9 0.33 10.3 0.5 1.5 2 0 0 2 2 2 0 Metalloenzyme superfamily Sulfotransfer_1 PF00685.27 OWF37727.1 - 2.5e-08 33.8 0.1 3.1e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF37727.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family EF-hand_1 PF00036.32 OWF37728.1 - 8.2e-40 131.4 13.6 1.2e-09 37.0 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37728.1 - 9.7e-34 115.7 4.1 1.5e-17 63.8 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF37728.1 - 1.1e-31 108.5 12.9 8.7e-15 54.3 1.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF37728.1 - 2.7e-30 101.7 9.1 1.8e-09 36.8 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37728.1 - 3.2e-27 92.8 9.2 1.2e-06 27.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF37728.1 - 1.5e-14 54.1 0.2 2.6e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF37728.1 - 1.3e-08 35.1 0.1 0.0016 18.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF37728.1 - 3.2e-08 33.4 1.3 0.0046 16.9 0.2 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF37728.1 - 8.5e-06 25.7 0.0 0.078 13.0 0.0 2.7 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OWF37728.1 - 4.7e-05 24.2 0.0 0.026 15.4 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain DUF5580 PF17743.1 OWF37728.1 - 0.00011 20.9 0.0 0.00012 20.7 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 OWF37728.1 - 0.00024 21.2 6.0 0.53 10.5 3.2 3.3 1 1 1 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 OWF37728.1 - 0.0026 17.7 0.2 1.3 9.0 0.0 3.2 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 OWF37728.1 - 0.0035 18.1 0.1 1.6 9.5 0.0 2.4 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) EFhand_Ca_insen PF08726.10 OWF37728.1 - 0.0052 16.8 0.1 0.021 14.9 0.0 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SurA_N_2 PF13623.6 OWF37728.1 - 0.017 15.0 0.5 0.067 13.1 0.2 1.8 1 1 1 2 2 2 0 SurA N-terminal domain RNA_pol_Rpb4 PF03874.16 OWF37728.1 - 0.018 15.4 1.5 1.8 8.9 0.4 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 TerB PF05099.13 OWF37728.1 - 0.031 14.2 0.0 2.6 8.0 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB SurA_N_3 PF13624.6 OWF37728.1 - 0.084 12.7 0.3 0.15 11.9 0.2 1.4 1 1 0 1 1 1 0 SurA N-terminal domain EF-hand_7 PF13499.6 OWF37729.1 - 9.2e-18 64.5 0.6 1.1e-11 45.0 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37729.1 - 4.1e-17 60.6 2.4 7.3e-05 22.4 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OWF37729.1 - 5.3e-17 60.0 2.9 8e-06 25.0 0.5 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF37729.1 - 1.6e-14 53.4 6.6 1.4e-12 47.3 0.8 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 OWF37729.1 - 2e-09 37.6 0.4 2.2e-05 24.7 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OWF37729.1 - 5.1e-05 22.6 0.3 0.0055 16.2 0.0 3.2 3 0 0 3 3 3 1 EF hand DUF5580 PF17743.1 OWF37729.1 - 0.013 14.1 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_4 PF12763.7 OWF37729.1 - 0.069 13.1 0.5 0.12 12.3 0.2 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3552 PF12072.8 OWF37730.1 - 1.2e-06 28.1 0.0 2.4 7.5 0.0 3.6 2 2 1 4 4 4 4 Domain of unknown function (DUF3552) Nup54 PF13874.6 OWF37730.1 - 0.053 13.6 15.9 2 8.5 1.0 4.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 MscS_porin PF12795.7 OWF37730.1 - 9.2 5.7 25.7 1.3 8.5 3.1 4.3 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain EF-hand_1 PF00036.32 OWF37731.1 - 4e-29 98.0 10.3 9.3e-09 34.2 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF37731.1 - 1.9e-28 98.7 11.5 7e-13 48.8 1.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF37731.1 - 4.7e-24 82.2 5.4 1.8e-07 30.5 0.6 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF37731.1 - 4e-23 79.8 8.3 1.6e-06 27.3 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF37731.1 - 3.6e-19 68.3 7.6 3.7e-10 39.5 0.5 4.0 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF37731.1 - 1.2e-07 32.0 0.3 0.00034 20.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF37731.1 - 1.1e-06 29.4 0.5 8e-05 23.5 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 OWF37731.1 - 6.2e-06 26.4 0.1 0.039 14.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF37731.1 - 4.4e-05 23.4 2.4 0.053 13.5 0.2 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF37731.1 - 0.0004 20.4 1.7 4 7.3 0.0 3.6 1 1 3 4 4 4 2 Caleosin related protein NADPH_Ox PF08414.10 OWF37731.1 - 0.00068 19.9 1.2 0.0038 17.5 0.2 2.1 1 1 1 2 2 2 1 Respiratory burst NADPH oxidase EF-hand_10 PF14788.6 OWF37731.1 - 0.0032 17.3 5.5 2.1 8.3 0.2 4.2 4 0 0 4 4 4 1 EF hand Adenine_glyco PF03352.13 OWF37731.1 - 0.0056 16.5 1.2 0.23 11.2 0.2 2.1 1 1 1 2 2 2 1 Methyladenine glycosylase Toprim_2 PF13155.6 OWF37731.1 - 0.019 15.4 0.4 1.1 9.7 0.1 2.6 1 1 2 3 3 3 0 Toprim-like PMBR PF09373.10 OWF37731.1 - 0.029 14.5 0.0 32 4.9 0.0 3.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat SBDS PF01172.18 OWF37731.1 - 0.052 13.6 0.4 1.9 8.6 0.0 2.3 1 1 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Rep_2 PF01719.17 OWF37731.1 - 0.053 13.3 0.1 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Plasmid replication protein SHOCT PF09851.9 OWF37731.1 - 0.06 13.1 0.0 4.2 7.2 0.0 3.2 2 0 0 2 2 2 0 Short C-terminal domain DUF5109 PF17134.4 OWF37731.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5109) SWIRM PF04433.17 OWF37731.1 - 0.12 12.7 0.6 0.39 11.1 0.2 2.0 1 1 1 2 2 2 0 SWIRM domain EF-hand_14 PF17959.1 OWF37731.1 - 0.12 12.7 0.9 5.1 7.5 0.4 2.6 1 1 1 2 2 2 0 EF-hand domain STAT1_TAZ2bind PF12162.8 OWF37731.1 - 0.22 11.2 1.1 46 3.7 0.0 3.7 4 0 0 4 4 4 0 STAT1 TAZ2 binding domain Com_YlbF PF06133.11 OWF37731.1 - 3.3 8.4 7.3 2.4 8.8 4.5 2.2 2 1 0 2 2 1 0 Control of competence regulator ComK, YlbF/YmcA MaoC_dehydratas PF01575.19 OWF37733.1 - 2.4e-18 65.9 0.0 3e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OWF37733.1 - 5.8e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 OWF37733.1 - 0.0003 21.1 0.0 0.00047 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily AMOP PF03782.17 OWF37734.1 - 1.3e-19 70.7 3.0 3.2e-19 69.4 3.0 1.7 1 0 0 1 1 1 1 AMOP domain TSP_1 PF00090.19 OWF37734.1 - 9.6e-07 28.9 10.7 6.9e-06 26.2 10.7 2.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain UCH PF00443.29 OWF37735.1 - 8.2e-42 143.5 4.3 8.2e-42 143.5 4.3 2.6 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF37735.1 - 1.3e-25 90.7 7.3 9.2e-25 87.9 7.3 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Aha1_N PF09229.11 OWF37736.1 - 8.2e-39 133.0 6.5 8.2e-39 133.0 6.5 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OWF37736.1 - 4.8e-06 26.8 0.7 3.4e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein HGTP_anticodon2 PF12745.7 OWF37736.1 - 0.0018 17.8 5.3 0.0072 15.9 5.7 1.7 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Phage_sheath_1C PF17482.2 OWF37736.1 - 0.0063 16.5 2.1 0.034 14.1 0.6 2.5 2 1 0 2 2 2 1 Phage tail sheath C-terminal domain Meth_synt_2 PF01717.18 OWF37736.1 - 0.056 12.7 1.3 0.063 12.5 0.1 1.6 2 0 0 2 2 2 0 Cobalamin-independent synthase, Catalytic domain SRI PF08236.11 OWF37736.1 - 0.06 13.5 7.6 0.37 11.0 1.9 2.6 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Spindle_Spc25 PF08234.12 OWF37736.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 UPF0154 PF03672.13 OWF37736.1 - 5 7.2 8.1 0.35 10.9 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DEAD PF00270.29 OWF37737.1 - 5.3e-41 140.3 0.0 1.3e-40 139.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF37737.1 - 5.7e-29 100.7 0.1 5.7e-29 100.7 0.1 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF37737.1 - 7.4e-10 39.1 0.0 7.4e-10 39.1 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OWF37737.1 - 0.001 19.4 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OWF37737.1 - 0.0021 17.8 0.0 0.036 13.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OWF37737.1 - 0.021 15.1 0.1 0.22 11.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 OWF37737.1 - 0.049 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain Spectrin PF00435.21 OWF37738.1 - 0.0022 18.5 27.2 0.011 16.2 1.8 5.5 6 0 0 6 6 6 2 Spectrin repeat KASH PF10541.9 OWF37738.1 - 0.0027 17.9 0.0 0.0073 16.6 0.0 1.7 1 0 0 1 1 1 1 Nuclear envelope localisation domain SesA PF17107.5 OWF37738.1 - 0.19 11.9 5.9 0.11 12.7 0.2 3.3 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Syncollin PF15138.6 OWF37739.1 - 0.089 13.0 2.7 0.24 11.6 0.2 2.2 1 1 1 2 2 2 0 Syncollin SMK-1 PF04802.15 OWF37740.1 - 3.4e-80 268.4 7.8 7e-80 267.4 7.8 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.18 OWF37740.1 - 0.00028 21.1 0.0 0.00075 19.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OWF37740.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 WH1 domain MOSC PF03473.17 OWF37741.1 - 2.7e-26 92.1 0.0 4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OWF37741.1 - 2.7e-24 85.3 0.0 4.6e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain bZIP_2 PF07716.15 OWF37742.1 - 5.2e-16 58.5 12.2 5.2e-16 58.5 12.2 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF37742.1 - 8.4e-05 22.6 7.9 8.4e-05 22.6 7.9 2.4 3 0 0 3 3 3 1 bZIP transcription factor AAA_11 PF13086.6 OWF37742.1 - 1.8 8.3 5.8 2.3 7.9 5.8 1.3 1 1 0 1 1 1 0 AAA domain bZIP_Maf PF03131.17 OWF37742.1 - 2.6 8.6 15.5 0.21 12.1 8.2 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor FAM27 PF15832.5 OWF37743.1 - 0.025 15.1 52.6 20 5.8 2.0 8.6 1 1 6 7 7 7 0 FAM27 D and E protein family APC_15aa PF05972.11 OWF37743.1 - 0.088 13.1 33.7 3.6e+02 1.7 0.0 18.6 26 0 0 26 26 26 0 APC 15 residue motif SepZ PF06066.11 OWF37743.1 - 0.56 10.5 8.8 41 4.5 0.1 5.3 3 2 4 7 7 7 0 SepZ FAM27 PF15832.5 OWF37744.1 - 0.0077 16.7 34.6 5.2 7.7 4.6 6.2 1 1 4 5 5 5 5 FAM27 D and E protein family ARD PF03079.14 OWF37745.1 - 0.45 10.7 9.1 0.28 11.3 7.5 1.5 1 1 0 1 1 1 0 ARD/ARD' family MOSC PF03473.17 OWF37746.1 - 2.2e-29 102.1 0.0 3.2e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OWF37746.1 - 1.9e-27 95.5 0.0 3.1e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Peptidase_M13 PF01431.21 OWF37746.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M13 TPR_MLP1_2 PF07926.12 OWF37747.1 - 0.0063 16.6 5.2 0.0063 16.6 5.2 8.3 1 1 7 8 8 8 4 TPR/MLP1/MLP2-like protein CC2-LZ PF16516.5 OWF37747.1 - 0.013 15.8 17.7 0.013 15.8 17.7 9.5 2 2 5 8 8 8 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Methyltr_RsmF_N PF17125.5 OWF37747.1 - 7.7 7.1 8.1 6.1 7.4 0.3 3.5 3 0 0 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF GSCFA PF08885.11 OWF37747.1 - 8.2 6.0 7.5 0.9 9.1 1.1 2.7 2 0 0 2 2 2 0 GSCFA family E1_DerP2_DerF2 PF02221.15 OWF37748.1 - 6.8e-21 75.1 2.4 6.8e-21 75.1 2.4 1.8 2 0 0 2 2 2 1 ML domain PX PF00787.24 OWF37748.1 - 3.1e-17 62.6 1.3 4.8e-17 62.0 0.3 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 OWF37748.1 - 3.1e-16 59.6 14.9 9.4e-14 51.5 14.9 2.4 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.18 OWF37748.1 - 2.8e-05 23.9 15.7 0.00038 20.2 11.2 2.7 2 1 0 2 2 2 2 BAR domain SHOCT PF09851.9 OWF37748.1 - 0.11 12.3 0.8 0.32 10.8 0.8 1.9 1 0 0 1 1 1 0 Short C-terminal domain BLYB PF05289.11 OWF37748.1 - 0.26 11.5 6.3 0.063 13.5 1.9 2.3 2 1 1 3 3 3 0 Borrelia hemolysin accessory protein E1_DerP2_DerF2 PF02221.15 OWF37749.1 - 3.2e-21 76.1 0.6 4e-21 75.8 0.6 1.1 1 0 0 1 1 1 1 ML domain DUF4504 PF14953.6 OWF37749.1 - 0.012 15.1 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Glyco_hydro_31 PF01055.26 OWF37751.1 - 4e-144 481.1 7.9 4e-144 481.1 7.9 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OWF37751.1 - 1.5e-26 92.5 1.4 1e-24 86.6 0.1 3.6 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 OWF37751.1 - 0.041 14.1 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Med8 PF10232.9 OWF37751.1 - 0.99 8.9 3.9 0.55 9.8 1.7 1.6 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PP1_inhibitor PF05361.12 OWF37752.1 - 1.7e-07 31.3 2.7 2.1e-07 31.0 2.7 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor MANEC PF07502.14 OWF37753.1 - 4.2e-16 59.0 8.1 8.7e-16 58.0 8.1 1.5 1 0 0 1 1 1 1 MANEC domain EB PF01683.18 OWF37753.1 - 0.003 17.8 14.0 0.0074 16.6 13.9 1.8 1 1 0 1 1 1 1 EB module PAN_3 PF08277.12 OWF37753.1 - 0.31 10.9 5.6 0.94 9.3 5.6 1.8 1 0 0 1 1 1 0 PAN-like domain FlgH PF02107.16 OWF37755.1 - 0.008 15.8 0.2 14 5.3 0.0 3.2 1 1 3 4 4 4 3 Flagellar L-ring protein LRR_adjacent PF08191.11 OWF37755.1 - 0.014 15.6 3.0 6.7 7.0 0.0 3.8 1 1 3 4 4 4 0 LRR adjacent DUF296 PF03479.15 OWF37755.1 - 0.047 14.1 6.7 2.7 8.4 6.7 3.0 1 1 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain PCMT PF01135.19 OWF37756.1 - 4.7e-78 261.8 0.4 5.8e-78 261.4 0.4 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OWF37756.1 - 6.3e-05 22.8 0.1 0.00041 20.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OWF37756.1 - 0.00014 21.3 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OWF37756.1 - 0.00077 19.0 0.2 0.002 17.7 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OWF37756.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OWF37756.1 - 0.0019 18.8 0.0 0.0045 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF37756.1 - 0.0025 17.7 0.0 0.0082 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF37756.1 - 0.0026 18.4 0.1 0.0098 16.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OWF37756.1 - 0.0096 15.9 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OWF37756.1 - 0.025 14.1 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 GCD14 PF08704.10 OWF37756.1 - 0.04 13.6 0.0 0.081 12.6 0.0 1.4 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 OWF37756.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CD36 PF01130.21 OWF37757.1 - 6.2e-33 114.0 5.5 4.4e-26 91.4 1.2 3.0 2 1 0 2 2 2 2 CD36 family Hol_Tox PF16935.5 OWF37757.1 - 1.5 8.9 3.6 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Putative Holin-like Toxin (Hol-Tox) DUF4236 PF14020.6 OWF37758.1 - 0.0017 18.9 0.3 0.25 11.9 0.2 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF4236) IF4E PF01652.18 OWF37759.1 - 2.6e-40 137.8 0.2 3.3e-40 137.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E LRAT PF04970.13 OWF37760.1 - 1.5e-18 67.4 10.0 1.1e-09 38.7 0.7 3.9 2 2 1 3 3 3 2 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 OWF37760.1 - 0.0066 16.3 0.2 2.3 8.0 0.1 2.5 2 0 0 2 2 2 2 PPPDE putative peptidase domain V-set_CD47 PF08204.11 OWF37760.1 - 0.012 15.5 1.6 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain TROVE PF05731.11 OWF37761.1 - 1.1e-57 196.1 0.3 5.1e-55 187.3 0.3 2.3 1 1 0 1 1 1 1 TROVE domain Biopterin_H PF00351.21 OWF37761.1 - 0.031 13.3 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Roc PF08477.13 OWF37762.1 - 2.4e-10 40.7 0.0 4.5e-06 26.9 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF37762.1 - 8.9e-09 35.4 0.6 2.3e-08 34.1 0.6 1.7 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 OWF37762.1 - 3.1e-08 34.1 0.0 1.7e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Death PF00531.22 OWF37762.1 - 3.1e-08 33.6 0.0 3.3e-06 27.2 0.1 2.6 2 0 0 2 2 2 1 Death domain Ank_4 PF13637.6 OWF37762.1 - 3.3e-06 27.5 0.0 3.7e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37762.1 - 0.00016 21.9 0.0 0.0024 18.1 0.0 2.8 2 1 1 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37762.1 - 0.0007 19.9 0.0 0.76 10.5 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ras PF00071.22 OWF37762.1 - 0.0022 17.6 0.1 0.28 10.7 0.1 2.6 2 0 0 2 2 2 1 Ras family Ank PF00023.30 OWF37762.1 - 0.036 14.5 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat RsgA_GTPase PF03193.16 OWF37762.1 - 0.052 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 OWF37762.1 - 0.083 13.4 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OWF37762.1 - 0.089 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ZZ PF00569.17 OWF37762.1 - 0.11 12.3 38.2 0.54 10.1 16.7 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type Fibrinogen_C PF00147.18 OWF37763.1 - 4.3e-74 249.0 9.2 6e-74 248.6 9.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF1664 PF07889.12 OWF37763.1 - 0.0065 16.5 0.7 0.0099 15.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ZapB PF06005.12 OWF37763.1 - 0.054 13.9 2.3 0.087 13.3 2.3 1.2 1 0 0 1 1 1 0 Cell division protein ZapB V_ATPase_I PF01496.19 OWF37763.1 - 0.069 11.1 0.3 0.09 10.7 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TolA_bind_tri PF16331.5 OWF37763.1 - 0.084 13.0 5.4 0.099 12.7 3.1 2.2 1 1 2 3 3 3 0 TolA binding protein trimerisation ATG16 PF08614.11 OWF37763.1 - 0.091 13.0 2.5 0.12 12.5 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GIT_CC PF16559.5 OWF37763.1 - 0.36 10.7 3.5 0.7 9.8 3.5 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4551 PF15087.6 OWF37764.1 - 1.7e-149 499.6 6.5 1.7e-102 344.3 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4551) DUF2181 PF10223.9 OWF37764.1 - 0.05 13.1 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) Synapsin_N PF10581.9 OWF37764.1 - 0.084 12.8 4.4 3.5 7.7 0.2 3.5 3 0 0 3 3 3 0 Synapsin N-terminal Kelch_1 PF01344.25 OWF37765.1 - 3.8e-33 112.8 13.0 3.3e-13 49.0 0.1 6.1 6 0 0 6 6 6 4 Kelch motif BTB PF00651.31 OWF37765.1 - 1.2e-26 93.1 0.3 2.9e-26 91.9 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 OWF37765.1 - 7e-23 80.1 2.2 8.3e-06 25.9 0.0 5.2 3 1 2 5 5 5 4 Kelch motif BACK PF07707.15 OWF37765.1 - 9.4e-19 67.4 0.7 9.4e-19 67.4 0.7 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 OWF37765.1 - 4.5e-17 61.9 0.7 0.0012 19.0 0.0 5.2 4 0 0 4 4 4 4 Galactose oxidase, central domain PI31_Prot_N PF11566.8 OWF37765.1 - 6.9e-12 45.5 0.0 2.6e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 PI31 proteasome regulator N-terminal Kelch_2 PF07646.15 OWF37765.1 - 2.4e-11 43.1 1.3 8.1e-05 22.4 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 OWF37765.1 - 2e-08 34.1 0.1 0.16 12.0 0.0 4.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF37765.1 - 2.9e-07 30.3 5.8 0.094 12.7 0.2 4.6 4 0 0 4 4 4 3 Kelch motif F-box-like PF12937.7 OWF37765.1 - 1.1e-06 28.4 0.1 3.4e-06 26.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF37765.1 - 1.1e-05 25.2 0.2 3.3e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OWF37765.1 - 0.0091 15.9 1.0 0.022 14.6 0.1 2.1 2 0 0 2 2 1 1 F-box Elongin_A PF06881.11 OWF37765.1 - 0.019 15.5 0.7 0.045 14.3 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C2H2_2 PF12756.7 OWF37765.1 - 0.13 12.6 1.5 0.29 11.5 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) TIP49 PF06068.13 OWF37766.1 - 3.4e-172 572.5 1.1 4.2e-172 572.2 1.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OWF37766.1 - 1.2e-21 76.6 0.0 4.2e-21 74.9 0.0 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OWF37766.1 - 6.6e-13 49.2 0.6 2.3e-08 34.5 0.1 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OWF37766.1 - 3.5e-11 43.1 0.4 3.7e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OWF37766.1 - 3.1e-07 30.8 0.4 0.0077 16.5 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 OWF37766.1 - 3.8e-05 23.7 0.1 0.0089 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF37766.1 - 4.5e-05 23.9 0.0 0.00028 21.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OWF37766.1 - 9.9e-05 22.0 0.0 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OWF37766.1 - 0.00013 21.7 0.1 0.26 11.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 OWF37766.1 - 0.0013 18.7 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OWF37766.1 - 0.0015 17.9 0.1 0.11 11.9 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OWF37766.1 - 0.002 18.6 0.0 0.027 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OWF37766.1 - 0.0027 18.1 3.2 0.075 13.4 3.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF37766.1 - 0.0044 17.2 0.0 0.05 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OWF37766.1 - 0.0066 16.0 0.1 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 OWF37766.1 - 0.0074 16.5 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 OWF37766.1 - 0.0084 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ResIII PF04851.15 OWF37766.1 - 0.0096 15.9 0.1 0.46 10.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OWF37766.1 - 0.0098 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 OWF37766.1 - 0.0099 15.6 0.4 0.3 10.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OWF37766.1 - 0.013 14.8 0.1 0.031 13.5 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 OWF37766.1 - 0.018 14.9 0.2 0.042 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OWF37766.1 - 0.019 14.4 0.8 0.047 13.1 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 OWF37766.1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 OWF37766.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Inositol_P PF00459.25 OWF37766.1 - 0.1 12.1 0.1 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Inositol monophosphatase family Parvo_NS1 PF01057.17 OWF37766.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cu2_monoox_C PF03712.15 OWF37770.1 - 1.7e-27 95.9 0.0 3.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF37770.1 - 9.1e-25 87.4 0.7 1.6e-24 86.6 0.7 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain adh_short PF00106.25 OWF37771.1 - 3.2e-46 157.3 0.4 4.3e-46 156.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF37771.1 - 3.7e-35 121.6 0.3 5.1e-35 121.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF37771.1 - 6.2e-10 39.3 0.1 9.1e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 OWF37771.1 - 5.3e-06 26.6 0.6 8.8e-06 25.9 0.6 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 OWF37771.1 - 0.009 16.0 0.2 0.014 15.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LT-IIB PF06453.11 OWF37771.1 - 0.064 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DUF1660 PF07874.11 OWF37772.1 - 0.23 12.0 0.3 0.23 12.0 0.3 2.4 2 1 0 2 2 2 0 Prophage protein (DUF1660) MafB19-deam PF14437.6 OWF37772.1 - 0.29 10.9 3.4 0.41 10.4 0.6 2.2 2 0 0 2 2 2 0 MafB19-like deaminase FAM76 PF16046.5 OWF37772.1 - 0.52 9.6 12.0 2.7 7.3 7.6 2.0 2 0 0 2 2 2 0 FAM76 protein ComS PF17584.2 OWF37773.1 - 8.2e-08 31.6 16.6 1.3e+02 2.2 0.0 12.9 13 0 0 13 13 13 0 Bacillus competence protein S Drf_FH1 PF06346.12 OWF37773.1 - 6.1e-06 26.0 0.0 0.019 14.7 0.0 2.4 1 1 1 2 2 2 2 Formin Homology Region 1 DUF4915 PF16261.5 OWF37773.1 - 1.4e-05 24.5 9.4 1.2 8.3 0.0 4.7 1 1 4 5 5 5 5 Domain of unknown function (DUF4915) DUF5486 PF17588.2 OWF37773.1 - 0.00028 20.7 23.5 66 3.5 0.0 11.1 1 1 12 13 13 13 0 Family of unknown function (DUF5486) PROL5-SMR PF15621.6 OWF37773.1 - 0.0013 19.2 2.9 11 6.6 0.3 3.9 1 1 2 3 3 3 2 Proline-rich submaxillary gland androgen-regulated family TrbH PF07283.11 OWF37773.1 - 0.0071 16.5 0.5 22 5.2 0.0 3.7 1 1 2 3 3 3 1 Conjugal transfer protein TrbH HLH PF00010.26 OWF37774.1 - 3.2e-16 59.0 0.1 6.1e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 OWF37774.1 - 0.52 9.9 7.3 0.3 10.7 5.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein MRI PF15325.6 OWF37774.1 - 0.56 11.3 4.1 0.23 12.6 1.5 1.8 2 0 0 2 2 2 0 Modulator of retrovirus infection GCOM2 PF15328.6 OWF37775.1 - 1.2e-11 45.4 14.3 3e-11 44.1 14.1 1.9 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 MFS_2 PF13347.6 OWF37776.1 - 1.5e-38 132.5 18.1 6.1e-26 91.0 2.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 OWF37776.1 - 2.3e-17 62.9 18.4 1.4e-12 47.2 8.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.8 OWF37776.1 - 0.00013 22.2 1.4 6.7 7.1 0.0 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF3382) zf-LITAF-like PF10601.9 OWF37776.1 - 0.076 13.3 17.1 0.28 11.5 3.7 4.0 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Linker_histone PF00538.19 OWF37777.1 - 1.1e-20 73.8 0.1 1.1e-20 73.8 0.1 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family SbcCD_C PF13558.6 OWF37777.1 - 0.037 14.3 0.9 0.093 13.0 0.1 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Sugar_tr PF00083.24 OWF37778.1 - 1.1e-33 116.8 19.1 1.6e-33 116.3 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37778.1 - 1.7e-25 89.7 50.9 3.1e-19 69.1 31.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OWF37778.1 - 2.7e-05 22.8 7.8 0.0017 16.9 0.5 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Pentapeptide_4 PF13599.6 OWF37779.1 - 2.2e-75 248.8 200.8 7.5e-08 32.4 16.7 11.3 1 1 12 13 13 13 13 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 OWF37779.1 - 4.3e-26 90.8 397.0 42 4.4 20.4 21.7 1 1 2 3 3 3 1 Pentapeptide repeats (9 copies) PMG PF05287.12 OWF37779.1 - 1.6e-08 34.8 3.6 6.7 6.7 1.6 8.5 1 1 2 3 3 3 2 PMG protein MFS_1 PF07690.16 OWF37780.1 - 2.3e-15 56.4 16.9 3.7e-15 55.7 16.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37780.1 - 7.5e-11 41.5 14.3 7.5e-11 41.5 14.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter S-l_SbsC_C PF18316.1 OWF37780.1 - 0.11 13.0 0.4 0.19 12.3 0.4 1.3 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain Sugar_tr PF00083.24 OWF37781.1 - 2e-20 73.1 0.6 2.6e-20 72.7 0.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF37781.1 - 2.8e-13 49.5 28.9 3.2e-08 32.9 7.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Av_adeno_fibre PF06536.11 OWF37782.1 - 0.086 12.7 8.3 60 3.6 0.0 7.1 3 2 5 8 8 8 0 Avian adenovirus fibre, N-terminal CBM-like PF14683.6 OWF37782.1 - 2 8.3 10.3 2.2e+03 -1.6 10.3 4.1 1 1 0 1 1 1 0 Polysaccharide lyase family 4, domain III Ints3 PF10189.9 OWF37783.1 - 1.4e-102 341.7 1.2 3.4e-102 340.5 1.2 1.7 1 0 0 1 1 1 1 Integrator complex subunit 3 zf-trcl PF13451.6 OWF37783.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain Muted PF14942.6 OWF37783.1 - 0.12 12.7 1.7 0.37 11.1 1.7 1.8 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein tRNA-synt_2 PF00152.20 OWF37784.1 - 5.8e-105 350.8 0.0 7.7e-105 350.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OWF37784.1 - 9.6e-10 38.3 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mito_fiss_reg PF05308.11 OWF37784.1 - 0.0082 16.2 0.5 0.12 12.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial fission regulator RQC PF09382.10 OWF37785.1 - 5.1e-27 93.9 0.1 1.1e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 OWF37785.1 - 6.9e-19 68.3 0.0 1.4e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF37785.1 - 2e-16 60.3 0.0 1.1e-15 57.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OWF37785.1 - 7.4e-16 58.6 3.4 2.2e-15 57.1 3.4 1.9 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 OWF37785.1 - 2.5e-07 30.6 0.0 5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 OWF37785.1 - 0.0023 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L36e PF01158.18 OWF37786.1 - 2.9e-39 133.2 10.7 3.3e-39 133.0 10.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e CdhC PF03598.15 OWF37786.1 - 0.074 12.9 0.8 0.11 12.4 0.8 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit C2 PF00168.30 OWF37787.1 - 8.4e-69 228.4 2.0 4.9e-23 81.4 0.1 3.5 3 0 0 3 3 3 3 C2 domain PRT_C PF08372.10 OWF37787.1 - 6.3e-09 35.8 0.2 2e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 OWF37787.1 - 1.2e-05 24.5 0.2 2e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin 2OG-FeII_Oxy_4 PF13661.6 OWF37787.1 - 0.0027 18.3 0.1 0.046 14.4 0.0 2.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PI3K_C2 PF00792.24 OWF37787.1 - 0.038 13.9 0.8 0.5 10.3 0.0 3.0 3 0 0 3 3 3 0 Phosphoinositide 3-kinase C2 Gelsolin PF00626.22 OWF37790.1 - 4.5e-27 93.8 0.0 3.8e-05 23.5 0.0 6.5 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 OWF37790.1 - 5.7e-08 32.7 0.4 1.2e-07 31.6 0.4 1.6 1 0 0 1 1 1 1 Villin headpiece domain HGTP_anticodon PF03129.20 OWF37790.1 - 0.0023 18.1 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain TPR_2 PF07719.17 OWF37791.1 - 3.4e-33 111.1 38.3 0.00073 19.5 0.0 20.5 24 0 0 24 24 21 5 Tetratricopeptide repeat TPR_19 PF14559.6 OWF37791.1 - 1.3e-30 105.7 29.2 0.00081 19.9 0.1 14.8 13 3 2 15 15 14 7 Tetratricopeptide repeat TPR_17 PF13431.6 OWF37791.1 - 3.5e-29 99.0 22.4 1.7e-05 24.8 0.0 15.0 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 OWF37791.1 - 1.7e-24 84.4 22.9 0.038 14.8 0.2 16.7 13 3 5 18 18 18 5 Tetratricopeptide repeat TPR_16 PF13432.6 OWF37791.1 - 2.5e-23 82.4 21.3 0.00029 21.4 0.0 12.8 15 2 2 17 17 15 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF37791.1 - 2.8e-20 71.2 40.4 1.1e-05 25.0 0.0 16.0 20 0 0 20 20 16 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF37791.1 - 4.1e-19 68.6 28.3 0.0019 18.4 0.6 11.6 9 3 2 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 OWF37791.1 - 7.5e-19 67.1 34.0 0.033 13.9 0.2 15.3 16 1 1 17 17 15 5 TPR repeat TPR_9 PF13371.6 OWF37791.1 - 1.6e-14 53.8 3.3 0.034 14.3 0.0 10.5 11 2 1 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF37791.1 - 2.7e-14 52.1 30.3 0.071 13.3 0.0 13.6 16 0 0 16 16 15 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF37791.1 - 2.7e-08 33.9 30.5 0.0016 18.6 0.9 8.8 10 0 0 10 10 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OWF37791.1 - 7.7e-06 26.1 0.1 26 5.8 0.0 7.1 7 0 0 7 7 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OWF37791.1 - 2.6e-05 23.9 3.5 0.21 11.2 0.1 6.0 7 0 0 7 7 7 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 OWF37791.1 - 2.9e-05 24.4 19.2 6.1 7.7 0.1 12.1 14 0 0 14 14 10 1 Tetratricopeptide repeat TPR_20 PF14561.6 OWF37791.1 - 5.9e-05 23.3 2.1 6.5 7.2 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 OWF37791.1 - 0.00025 20.2 0.4 0.42 9.6 0.0 2.7 2 0 0 2 2 2 2 Coatomer WD associated region ChAPs PF09295.10 OWF37791.1 - 0.00052 19.1 12.6 1.1 8.2 0.1 6.5 7 1 0 8 8 8 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 OWF37791.1 - 0.0016 17.7 8.8 0.074 12.2 0.3 6.0 5 2 1 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 OWF37791.1 - 0.0029 17.4 4.1 2.9 7.6 0.1 5.5 6 0 0 6 6 6 1 26S proteasome subunit RPN7 PPR PF01535.20 OWF37791.1 - 0.0052 16.9 5.4 6.6 7.2 0.0 5.9 6 0 0 6 6 5 1 PPR repeat TPR_7 PF13176.6 OWF37791.1 - 0.034 14.2 19.8 7.1 6.9 0.1 10.0 11 0 0 11 11 9 0 Tetratricopeptide repeat PPR_1 PF12854.7 OWF37791.1 - 0.037 13.7 0.2 5.7 6.7 0.0 3.0 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 OWF37791.1 - 0.13 12.5 0.7 13 6.1 0.0 4.3 5 0 0 5 5 5 0 PPR repeat family TPR_10 PF13374.6 OWF37791.1 - 0.26 11.2 17.7 25 4.9 0.0 8.8 10 0 0 10 10 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF37791.1 - 1.6 8.8 10.2 13 6.0 0.1 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 OWF37791.1 - 2.3 7.4 14.6 8.8 5.4 0.4 5.8 5 2 1 7 7 7 0 FAT domain Maf PF02545.14 OWF37792.1 - 0.0007 19.5 16.6 27 4.6 0.0 7.6 7 1 0 8 8 8 1 Maf-like protein B_solenoid_ydck PF18836.1 OWF37792.1 - 0.0066 16.2 0.1 57 3.8 0.0 4.6 5 0 0 5 5 5 0 Beta solenoid repeat from YDCK FeoB_C PF07664.12 OWF37792.1 - 0.0094 15.6 0.0 81 3.0 0.0 5.0 2 1 6 8 8 8 0 Ferrous iron transport protein B C terminus Erythro-docking PF09277.11 OWF37792.1 - 0.034 14.0 4.6 97 3.0 0.0 5.8 7 0 0 7 7 7 0 Erythronolide synthase, docking DBI_PRT PF02277.17 OWF37792.1 - 0.49 9.6 20.7 3.6 6.7 0.1 5.8 1 1 6 7 7 7 0 Phosphoribosyltransferase DUF2273 PF10031.9 OWF37792.1 - 2.6 8.1 30.8 7.2 6.7 0.3 7.5 6 2 2 8 8 8 0 Small integral membrane protein (DUF2273) Neur_chan_LBD PF02931.23 OWF37793.1 - 3e-35 121.6 0.0 4.4e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF37793.1 - 3.3e-13 50.3 2.9 3.3e-13 50.3 2.9 2.1 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF37794.1 - 9e-40 136.4 1.2 1.7e-39 135.5 1.2 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF37794.1 - 5.6e-15 56.1 2.7 5.6e-15 56.1 2.7 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 OWF37794.1 - 4.9 7.5 6.5 28 5.1 2.1 3.1 2 1 0 2 2 2 0 Orf78 (ac78) CUB PF00431.20 OWF37795.1 - 8.7e-29 100.1 1.8 5.5e-14 52.4 0.1 2.3 2 0 0 2 2 2 2 CUB domain VHS PF00790.19 OWF37796.1 - 2.4e-40 137.6 3.4 1e-39 135.6 0.0 2.9 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 OWF37796.1 - 3.4e-24 85.3 0.1 3.4e-24 85.3 0.1 2.5 3 0 0 3 3 3 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 OWF37796.1 - 1.1e-20 73.0 5.9 2.4e-20 71.8 5.9 1.7 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 OWF37796.1 - 2.7e-16 59.6 6.3 8.3e-16 58.1 0.4 3.4 3 0 0 3 3 3 1 GAT domain NUP PF06516.11 OWF37796.1 - 0.034 13.4 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) DUF4523 PF15023.6 OWF37796.1 - 0.12 12.2 0.5 2.6 7.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) DUF4375 PF14300.6 OWF37796.1 - 0.14 12.4 4.0 9.4 6.5 0.0 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4375) PCRF PF03462.18 OWF37796.1 - 1.7 8.5 7.1 0.61 9.9 3.0 2.4 2 1 1 3 3 3 0 PCRF domain WD40 PF00400.32 OWF37797.1 - 1.6e-17 63.5 19.5 0.02 15.8 0.2 9.5 10 0 0 10 10 10 6 WD domain, G-beta repeat EF-hand_7 PF13499.6 OWF37797.1 - 4.1e-10 40.0 0.0 1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF37797.1 - 4.6e-10 39.2 0.1 1.5e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF37797.1 - 4.5e-05 22.7 0.0 0.026 14.1 0.0 2.9 2 0 0 2 2 2 2 EF hand ANAPC4_WD40 PF12894.7 OWF37797.1 - 0.00014 22.1 1.5 2.3 8.6 0.0 5.7 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OWF37797.1 - 0.0022 16.8 1.8 0.99 8.1 0.0 3.8 4 1 1 5 5 5 2 Nup133 N terminal like EF-hand_6 PF13405.6 OWF37797.1 - 0.0037 17.1 0.0 4 7.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF37797.1 - 0.0094 15.4 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 EF hand Nup160 PF11715.8 OWF37797.1 - 0.014 14.1 1.1 5.4 5.5 0.0 3.9 3 1 1 5 5 5 0 Nucleoporin Nup120/160 OST-HTH PF12872.7 OWF37797.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 OST-HTH/LOTUS domain LSDAT_euk PF18139.1 OWF37798.1 - 3.9e-69 233.0 0.0 8.4e-69 231.9 0.0 1.6 2 0 0 2 2 2 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF37798.1 - 3.6e-25 88.4 0.1 1.1e-24 86.9 0.1 1.7 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 OWF37798.1 - 1.4e-14 53.9 20.2 2.3e-14 53.2 20.2 1.3 1 0 0 1 1 1 1 Ion transport protein LDcluster4 PF18306.1 OWF37798.1 - 0.00044 19.9 0.7 0.24 11.0 0.2 2.3 2 0 0 2 2 2 2 SLOG cluster4 family Plasmid_RAQPRD PF09686.10 OWF37798.1 - 0.025 14.8 0.7 6.4 7.1 0.1 2.9 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF3461 PF11944.8 OWF37798.1 - 0.082 13.0 0.7 0.37 10.9 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) T3SchapCesA PF11439.8 OWF37798.1 - 0.085 13.0 0.4 0.21 11.8 0.4 1.6 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA TCR PF03638.15 OWF37800.1 - 1.2e-23 83.2 58.3 3.5e-12 46.4 25.5 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 OWF37800.1 - 0.024 14.8 45.8 0.21 11.7 19.0 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 CSN4_RPN5_eIF3a PF18420.1 OWF37801.1 - 9.1e-23 80.2 5.1 2.2e-22 78.9 5.1 1.7 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain PCI PF01399.27 OWF37801.1 - 1.5e-17 64.0 0.3 1.5e-17 64.0 0.3 2.4 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.9 OWF37801.1 - 0.00034 20.4 2.5 0.0005 19.8 1.7 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 Mo25 PF08569.11 OWF37801.1 - 0.00099 18.6 0.1 0.0036 16.7 0.1 1.9 1 1 0 1 1 1 1 Mo25-like TPR_14 PF13428.6 OWF37801.1 - 0.11 13.4 2.2 0.34 11.8 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF37801.1 - 0.17 12.4 1.9 22 5.6 0.0 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF2678 PF10856.8 OWF37802.1 - 0.00019 21.3 3.9 0.00029 20.7 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF4267 PF14087.6 OWF37802.1 - 0.035 14.2 2.6 0.097 12.8 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) Phage_holin_2_4 PF16082.5 OWF37802.1 - 0.18 11.5 0.5 0.32 10.7 0.5 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SPC12 PF06645.13 OWF37802.1 - 2.3 8.4 8.7 0.31 11.1 3.2 2.0 1 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF5528 PF17666.1 OWF37804.1 - 3.3e-05 23.9 0.9 8.5e-05 22.6 0.9 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5528) Utp12 PF04003.12 OWF37805.1 - 0.0007 19.9 0.0 0.0034 17.7 0.0 2.2 1 1 0 1 1 1 1 Dip2/Utp12 Family zf-C4pol PF14260.6 OWF37805.1 - 1.1 9.8 9.8 0.92 10.0 6.3 2.6 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta SMG1 PF15785.5 OWF37806.1 - 6.6e-206 685.5 8.6 1.6e-205 684.2 8.6 1.7 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 OWF37806.1 - 4.9e-52 177.2 0.0 1.4e-51 175.7 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OWF37806.1 - 1.5e-11 43.9 0.0 5.3e-11 42.1 0.0 2.1 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OWF37806.1 - 0.0022 18.4 0.2 0.0022 18.4 0.2 5.9 6 1 1 7 7 7 2 FKBP12-rapamycin binding domain HEAT PF02985.22 OWF37806.1 - 0.021 15.1 0.3 4.9 7.7 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat RhoGEF PF00621.20 OWF37806.1 - 0.43 10.8 8.2 0.07 13.4 0.5 3.7 3 0 0 3 3 3 0 RhoGEF domain FYVE PF01363.21 OWF37808.1 - 2.2e-17 62.9 11.9 6.3e-17 61.5 11.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 OWF37808.1 - 0.005 16.8 12.7 4.1 7.6 0.1 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 OWF37808.1 - 0.029 14.3 0.3 0.08 12.8 0.3 1.7 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AAA_12 PF13087.6 OWF37809.1 - 4.5e-38 130.9 0.0 1.2e-37 129.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OWF37809.1 - 1.1e-24 87.6 12.4 9.3e-13 48.6 0.4 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 OWF37809.1 - 2.1e-09 37.9 1.2 3.7e-05 24.1 0.1 4.2 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 OWF37809.1 - 2.9e-06 27.2 0.8 0.0032 17.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 OWF37809.1 - 7.7e-05 22.8 2.1 0.025 14.6 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OWF37809.1 - 0.0025 17.4 3.0 0.18 11.3 3.0 3.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain eIF_4EBP PF05456.11 OWF37809.1 - 0.003 17.5 1.4 0.099 12.6 0.1 2.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PhoH PF02562.16 OWF37809.1 - 0.0043 16.5 3.7 0.2 11.1 0.0 3.0 3 0 0 3 3 3 2 PhoH-like protein DUF2075 PF09848.9 OWF37809.1 - 0.0055 16.0 0.6 0.021 14.1 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OWF37809.1 - 0.03 14.6 0.5 0.55 10.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 OWF37809.1 - 0.038 13.7 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OWF37809.1 - 0.1 13.0 0.0 0.39 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Histone PF00125.24 OWF37809.1 - 7.5 6.9 7.1 8.4 6.8 0.2 3.7 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 eIF_4EBP PF05456.11 OWF37810.1 - 0.003 17.5 0.3 0.026 14.5 0.1 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ECSIT PF06239.11 OWF37811.1 - 1.6e-64 217.1 4.1 1.6e-64 217.1 4.1 1.7 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.6 OWF37811.1 - 4.2e-35 120.9 2.4 5.9e-35 120.5 0.0 2.2 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein Homeodomain PF00046.29 OWF37814.1 - 4.3e-23 80.9 3.4 8.1e-23 80.0 3.4 1.5 1 0 0 1 1 1 1 Homeodomain DUF410 PF04190.13 OWF37815.1 - 9.8e-82 274.6 0.1 1.2e-81 274.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_6 PF13174.6 OWF37815.1 - 0.012 16.2 0.6 0.26 12.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 OWF37815.1 - 0.07 13.1 0.2 0.24 11.3 0.0 1.9 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_2 PF07719.17 OWF37815.1 - 1.8 8.8 5.1 14 6.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CDK2AP PF09806.9 OWF37816.1 - 6.8e-25 88.5 0.5 7.8e-25 88.3 0.5 1.3 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein TraK PF06586.11 OWF37816.1 - 0.12 12.1 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 TraK protein WD40 PF00400.32 OWF37817.1 - 1.6e-06 28.7 1.8 0.69 10.9 0.4 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat UL41A PF17591.2 OWF37817.1 - 0.0049 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Herpesvirus UL41A DUF4746 PF15928.5 OWF37819.1 - 0.01 15.3 3.5 0.012 15.0 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 OWF37819.1 - 0.028 14.2 3.7 0.033 14.0 3.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 OWF37819.1 - 0.042 13.3 10.0 0.044 13.2 10.0 1.0 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 OWF37819.1 - 0.68 9.1 4.6 0.8 8.9 4.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 OWF37819.1 - 4.6 5.9 4.7 5.2 5.7 4.7 1.0 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 OWF37819.1 - 9.6 4.2 7.7 11 4.1 7.7 1.0 1 0 0 1 1 1 0 Hsp70 protein PSK PF06404.12 OWF37819.1 - 9.7 7.3 11.0 14 6.8 11.0 1.2 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) Cue1_U7BR PF18499.1 OWF37820.1 - 0.00016 21.6 2.4 6.4 6.9 0.0 4.4 4 0 0 4 4 4 3 Ubc7p-binding region of Cue1 Lipase_GDSL_2 PF13472.6 OWF37822.1 - 1.4e-08 35.3 0.0 1.7e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF37822.1 - 0.041 13.9 0.0 0.062 13.3 0.0 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Aminotran_5 PF00266.19 OWF37823.1 - 1.5e-06 27.4 0.0 4.2e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OWF37823.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family VKG_Carbox PF05090.14 OWF37824.1 - 5.3e-159 529.7 16.3 6.7e-159 529.3 16.3 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Cupin_2 PF07883.11 OWF37824.1 - 0.00069 19.3 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 Cupin domain DoxX PF07681.12 OWF37824.1 - 0.0015 19.1 6.5 0.0024 18.4 2.2 2.6 2 0 0 2 2 2 1 DoxX Na_H_Exchanger PF00999.21 OWF37825.1 - 8.7e-29 100.5 38.3 1.2e-28 100.0 38.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ubiquitin PF00240.23 OWF37826.1 - 1.8e-17 62.8 0.1 8e-17 60.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family zf-AN1 PF01428.16 OWF37826.1 - 2.4e-09 37.2 8.2 4.4e-09 36.3 8.2 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 OWF37826.1 - 0.00041 20.7 0.1 0.00041 20.7 0.1 3.0 3 1 0 3 3 3 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OWF37826.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Helicase_C PF00271.31 OWF37827.1 - 1.7e-26 92.7 0.1 2.4e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF37828.1 - 5.4e-36 124.0 0.2 6.9e-36 123.6 0.2 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OWF37828.1 - 0.00015 21.6 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF37828.1 - 0.00023 21.5 0.2 0.00034 21.0 0.2 1.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OWF37828.1 - 0.00044 20.3 0.1 0.00066 19.7 0.1 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OWF37828.1 - 0.033 13.7 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 OWF37828.1 - 0.062 13.3 0.1 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 OWF37828.1 - 0.072 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Helicase TniB PF05621.11 OWF37828.1 - 0.081 12.3 0.2 0.33 10.3 0.1 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 OWF37828.1 - 0.098 12.9 1.4 0.8 10.0 1.4 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OWF37828.1 - 0.14 11.3 0.1 0.44 9.7 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UTP25 PF06862.12 OWF37828.1 - 0.21 10.3 0.4 0.47 9.2 0.0 1.6 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PfkB PF00294.24 OWF37829.1 - 3.4e-70 236.7 0.1 4.1e-70 236.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase AhpC-TSA_2 PF13911.6 OWF37831.1 - 4.1e-12 46.2 0.0 7.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme MerT PF02411.15 OWF37831.1 - 0.053 13.5 1.1 0.1 12.7 1.1 1.4 1 0 0 1 1 1 0 MerT mercuric transport protein adh_short_C2 PF13561.6 OWF37832.1 - 2.2e-54 184.5 0.1 2.6e-54 184.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF37832.1 - 5e-49 166.4 0.6 6e-49 166.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF37832.1 - 1.1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF37832.1 - 8.4e-08 32.0 0.0 4e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OWF37832.1 - 0.0071 16.4 0.2 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OWF37832.1 - 0.013 15.8 0.0 0.046 14.0 0.0 1.8 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 OWF37832.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 OWF37832.1 - 0.093 12.1 0.2 0.52 9.6 0.2 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ank_2 PF12796.7 OWF37833.1 - 2.5e-22 79.3 0.2 8.6e-09 35.9 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF37833.1 - 2e-21 75.7 0.4 0.0014 18.9 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF37833.1 - 8.1e-16 58.2 0.3 0.0017 18.8 0.0 6.0 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37833.1 - 2.1e-11 43.0 2.2 0.036 14.6 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OWF37833.1 - 4.5e-09 36.3 4.1 0.15 12.6 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Trypsin_2 PF13365.6 OWF37833.1 - 0.0003 21.7 0.0 0.00074 20.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ank_2 PF12796.7 OWF37834.1 - 1.3e-06 28.9 0.5 0.0002 21.8 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF37834.1 - 9.8e-05 22.6 0.0 1.8 8.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37834.1 - 0.034 14.7 0.8 40 5.3 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat TSP_1 PF00090.19 OWF37838.1 - 1.1e-15 57.5 38.4 4.3e-08 33.3 10.7 3.9 2 1 1 3 3 3 2 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF37838.1 - 1.2e-13 51.4 0.1 4.5e-13 49.6 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF37838.1 - 2e-10 40.9 0.1 2e-10 40.9 0.1 2.9 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 OWF37838.1 - 1.6e-09 37.7 0.0 3.9e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain CarbopepD_reg_2 PF13715.6 OWF37838.1 - 0.00032 20.7 7.4 0.13 12.3 0.5 2.6 2 0 0 2 2 2 2 CarboxypepD_reg-like domain Ig_C17orf99 PF17736.1 OWF37838.1 - 0.096 12.7 1.2 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 C17orf99 Ig domain SOG2 PF10428.9 OWF37838.1 - 2.3 7.3 12.4 3.6 6.7 12.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SpoIIIAH PF12685.7 OWF37838.1 - 9.7 5.9 7.2 11 5.8 0.2 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein VWA_2 PF13519.6 OWF37839.1 - 1.8e-05 25.3 0.1 8.2e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain ASH PF15780.5 OWF37839.1 - 0.012 15.8 0.2 0.091 13.0 0.2 2.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF5643 PF18705.1 OWF37839.1 - 0.099 12.6 1.5 0.3 11.1 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5643) TSP_1 PF00090.19 OWF37842.1 - 1.2e-12 47.8 34.7 4.3e-07 30.1 13.4 3.4 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF37842.1 - 1.5e-05 25.5 0.9 1.5e-05 25.5 0.9 3.2 3 1 0 3 3 3 1 Immunoglobulin domain VWA_2 PF13519.6 OWF37843.1 - 4.7e-07 30.4 0.1 2.6e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OWF37843.1 - 0.00013 22.2 0.4 0.00035 20.9 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Adeno_E3_CR2 PF02439.15 OWF37843.1 - 2 8.2 5.7 4.9 7.0 5.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TSP_1 PF00090.19 OWF37844.1 - 5.7e-15 55.3 36.8 3.1e-08 33.7 7.0 3.4 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF37844.1 - 6e-13 49.2 0.1 1.7e-12 47.7 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF37844.1 - 6.4e-11 42.4 0.1 6.4e-11 42.4 0.1 2.8 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 OWF37844.1 - 1.5e-09 37.8 0.0 3.3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 OWF37844.1 - 0.00013 22.1 0.3 0.033 14.4 0.0 2.6 1 1 1 2 2 2 2 Immunoglobulin V-set domain B277 PF17623.2 OWF37844.1 - 1.8 7.5 6.6 0.11 11.6 1.2 1.6 2 0 0 2 2 2 0 Domain of unknown function MH2 PF03166.14 OWF37845.1 - 1e-75 254.1 0.0 1.5e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 OWF37845.1 - 1.2e-39 134.7 0.1 2.2e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 MH1 domain Glyco_transf_11 PF01531.16 OWF37846.1 - 1.6e-28 99.8 0.9 2.5e-28 99.1 0.9 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 11 Reprolysin_2 PF13574.6 OWF37847.1 - 8.8e-29 100.8 0.3 1.7e-28 99.9 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF37847.1 - 8e-25 88.1 0.6 8e-25 88.1 0.6 2.7 2 2 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF37847.1 - 6.8e-19 68.6 0.0 1.6e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OWF37847.1 - 3.2e-10 40.7 25.7 3.2e-10 40.7 25.7 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.6 OWF37847.1 - 6.6e-07 29.2 0.9 2.5e-06 27.3 0.9 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 OWF37847.1 - 0.00034 20.8 0.0 0.00086 19.6 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 OWF37847.1 - 0.00043 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.6 OWF37847.1 - 0.019 15.0 1.3 0.082 13.0 1.3 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Peptidase_M66 PF10462.9 OWF37847.1 - 0.046 12.7 0.3 0.086 11.8 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 MCC-bdg_PDZ PF10506.9 OWF37848.1 - 4.4e-37 125.9 12.0 5.4e-23 80.8 1.3 5.8 8 0 0 8 8 8 2 PDZ domain of MCC-2 bdg protein for Usher syndrome FAM76 PF16046.5 OWF37848.1 - 1.2e-05 24.9 0.9 1.2e-05 24.9 0.9 5.1 3 3 2 5 5 5 1 FAM76 protein EF-hand_7 PF13499.6 OWF37848.1 - 0.00018 21.9 0.6 0.0017 18.8 0.6 2.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF37848.1 - 0.00037 20.2 0.5 0.0013 18.5 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OWF37848.1 - 0.0034 16.8 1.6 0.0056 16.2 0.3 2.2 2 0 0 2 2 2 1 EF hand CENP-F_leu_zip PF10473.9 OWF37848.1 - 0.012 15.7 0.7 0.012 15.7 0.7 7.3 6 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3813 PF12758.7 OWF37848.1 - 0.12 12.7 4.8 0.36 11.2 2.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) EF-hand_5 PF13202.6 OWF37848.1 - 0.14 11.7 0.2 0.46 10.1 0.2 1.9 1 0 0 1 1 1 0 EF hand DNA_photolyase PF00875.18 OWF37848.1 - 0.31 11.0 3.6 0.72 9.8 0.5 3.1 2 1 1 3 3 3 0 DNA photolyase Mesd PF10185.9 OWF37849.1 - 2.5e-70 235.4 7.8 3.4e-70 235.0 7.8 1.2 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor TMEM132D_C PF15706.5 OWF37849.1 - 0.062 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Inhibitor_I53 PF11714.8 OWF37849.1 - 0.066 13.4 4.1 0.22 11.7 0.1 2.3 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Afi1 PF07792.12 OWF37849.1 - 1.4 9.4 10.2 6.6 7.2 3.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking UPF0239 PF06783.11 OWF37849.1 - 2.6 8.3 6.9 47 4.2 5.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) CRA PF06589.11 OWF37849.1 - 3.2 7.9 11.2 0.23 11.6 0.2 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) UCH PF00443.29 OWF37850.1 - 3.9e-51 174.0 0.0 3.9e-51 174.0 0.0 2.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 OWF37850.1 - 9.6e-27 93.5 1.8 9.6e-27 93.5 1.8 3.7 2 1 0 3 3 3 1 USP8 dimerisation domain WW PF00397.26 OWF37850.1 - 1.5e-10 41.0 2.8 2.3e-10 40.4 1.5 2.0 2 0 0 2 2 2 1 WW domain UCH_1 PF13423.6 OWF37850.1 - 2.5e-10 40.5 2.4 2.5e-10 40.5 2.4 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 OWF37850.1 - 2.8e-09 37.4 0.0 2e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain zf-MIZ PF02891.20 OWF37850.1 - 0.05 13.3 0.4 0.18 11.6 0.4 2.0 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF5401 PF17380.2 OWF37850.1 - 0.79 7.7 92.8 1.2 7.1 92.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Sin3a_C PF16879.5 OWF37851.1 - 5.5e-83 279.0 14.9 5.5e-83 279.0 14.9 2.3 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 OWF37851.1 - 3.9e-47 158.1 9.9 1.3e-19 70.0 0.8 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OWF37851.1 - 2.9e-42 142.7 0.6 9.8e-42 141.0 0.6 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor YcaO_C PF18381.1 OWF37851.1 - 0.04 13.8 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain tRNA-synt_2 PF00152.20 OWF37851.1 - 0.33 10.0 4.7 0.77 8.8 3.5 2.0 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) MH2 PF03166.14 OWF37852.1 - 3e-80 268.8 0.3 4e-80 268.4 0.3 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 OWF37852.1 - 7.9e-43 144.9 0.9 1.6e-42 143.9 0.9 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 OWF37852.1 - 0.00046 20.0 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Leo1 PF04004.13 OWF37853.1 - 6.6e-49 165.9 1.4 7.9e-49 165.7 0.0 1.8 2 0 0 2 2 2 1 Leo1-like protein Peptidase_S49_N PF08496.10 OWF37853.1 - 1.2 9.2 3.1 2.7 8.0 3.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HSDR_N_2 PF13588.6 OWF37855.1 - 0.059 13.4 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) VRR_NUC PF08774.11 OWF37855.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 VRR-NUC domain DUF4200 PF13863.6 OWF37857.1 - 0.088 13.2 2.6 0.12 12.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-CCHC PF00098.23 OWF37858.1 - 1.9e-05 24.5 2.2 1.9e-05 24.5 2.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 OWF37858.1 - 1.4 8.7 6.6 8.3 6.2 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 OWF37858.1 - 1.7 8.7 11.6 0.45 10.5 4.3 2.3 2 0 0 2 2 2 0 Zinc knuckle PTS_2-RNA PF01885.16 OWF37859.1 - 2e-12 47.5 0.0 2.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF374 PF04028.13 OWF37859.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF374) PHD PF00628.29 OWF37860.1 - 0.00015 21.5 11.9 0.00063 19.6 5.6 2.8 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 OWF37860.1 - 0.0012 18.3 11.6 0.0016 17.9 5.8 2.5 2 1 0 2 2 2 1 PHD-finger zf-CHY PF05495.12 OWF37860.1 - 0.024 15.1 4.8 0.047 14.2 4.8 1.5 1 1 0 1 1 1 0 CHY zinc finger PHD_4 PF16866.5 OWF37860.1 - 0.045 13.9 7.9 0.33 11.1 7.9 2.2 1 1 0 1 1 1 0 PHD-finger C1_1 PF00130.22 OWF37860.1 - 0.054 13.4 8.3 0.08 12.8 0.7 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 OWF37860.1 - 0.17 12.2 6.3 0.65 10.3 6.3 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-BED PF02892.15 OWF37860.1 - 0.22 11.6 4.1 5 7.2 0.0 2.7 3 0 0 3 3 3 0 BED zinc finger MFS_1 PF07690.16 OWF37861.1 - 3.4e-37 128.2 23.3 1.8e-22 79.8 6.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OWF37861.1 - 0.00071 18.3 22.0 0.0037 15.9 4.9 4.0 2 2 2 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.24 OWF37861.1 - 0.00078 18.4 4.7 0.00078 18.4 4.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4996 PF16387.5 OWF37861.1 - 0.023 15.2 0.1 0.045 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function LacY_symp PF01306.19 OWF37861.1 - 0.029 13.2 20.3 0.036 12.8 8.2 2.3 2 1 0 2 2 2 0 LacY proton/sugar symporter VPS13_C PF16909.5 OWF37861.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal CoxIIa PF08113.11 OWF37861.1 - 5 7.0 7.4 6.7 6.6 5.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family MFS_1 PF07690.16 OWF37862.1 - 9e-42 143.2 22.0 1e-24 87.1 12.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF37862.1 - 0.0001 21.3 23.7 0.0035 16.3 3.4 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter CoxIIa PF08113.11 OWF37862.1 - 4.5 7.2 7.4 0.98 9.3 2.8 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Paramecium_SA PF01508.16 OWF37863.1 - 2e-10 40.9 118.6 2.5 8.6 9.7 11.0 1 1 3 4 4 4 3 Paramecium surface antigen domain FbpC_C_terminal PF17845.1 OWF37863.1 - 3.2e-06 27.2 21.8 71 3.6 0.0 13.4 4 3 12 18 18 18 0 FbpC C-terminal regulatory nucleotide binding domain DUF3396 PF11876.8 OWF37863.1 - 0.00015 21.3 7.0 22 4.4 0.0 6.8 2 1 3 7 7 7 2 Protein of unknown function (DUF3396) Paramecium_SA PF01508.16 OWF37864.1 - 0.00028 21.2 39.7 0.61 10.5 11.2 4.1 1 1 2 3 3 3 2 Paramecium surface antigen domain FbpC_C_terminal PF17845.1 OWF37864.1 - 0.0048 17.0 2.0 17 5.6 0.0 4.6 2 1 3 5 5 5 1 FbpC C-terminal regulatory nucleotide binding domain DUF3396 PF11876.8 OWF37864.1 - 0.14 11.6 0.3 16 4.8 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3396) Rap1_C PF11626.8 OWF37864.1 - 0.96 9.6 19.7 20 5.4 1.3 5.2 1 1 3 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SAMP PF05924.11 OWF37864.1 - 1.2 8.5 82.3 6.2 6.3 0.2 15.7 18 0 0 18 18 18 0 SAMP Motif Neur_chan_LBD PF02931.23 OWF37865.1 - 3.1e-24 85.6 0.0 4.2e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF37865.1 - 3.4e-17 63.3 11.4 1.8e-14 54.4 9.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2689 PF10894.8 OWF37865.1 - 0.04 13.7 0.1 1.2 9.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) BACK PF07707.15 OWF37866.1 - 9e-25 86.8 4.2 1.5e-24 86.1 2.1 2.4 2 1 1 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 OWF37866.1 - 3.2e-24 85.3 0.4 3.2e-24 85.3 0.4 2.3 2 1 1 3 3 3 1 BTB/POZ domain Kelch_1 PF01344.25 OWF37866.1 - 7.7e-21 73.4 3.8 1.3e-08 34.3 0.6 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 OWF37866.1 - 1.2e-13 50.8 1.8 0.00013 22.1 0.0 4.3 2 1 2 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OWF37866.1 - 1.1e-07 31.7 2.3 0.0016 18.4 0.1 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 OWF37866.1 - 2.7e-07 30.5 0.5 0.00033 20.6 0.0 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF37866.1 - 1.4e-05 24.9 1.2 0.13 12.3 0.1 3.6 3 0 0 3 3 3 2 Kelch motif DUF3342 PF11822.8 OWF37866.1 - 0.018 15.2 0.1 0.052 13.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Kelch_3 PF13415.6 OWF37866.1 - 0.087 13.1 3.2 82 3.7 0.2 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Neur_chan_LBD PF02931.23 OWF37867.1 - 1.7e-31 109.3 0.2 2.5e-31 108.8 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF37867.1 - 1.6e-17 64.4 14.0 1.4e-15 58.1 8.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Curto_V3 PF07436.11 OWF37867.1 - 0.088 13.2 0.2 0.24 11.8 0.2 1.7 1 0 0 1 1 1 0 Curtovirus V3 protein DpnI_C PF17726.1 OWF37868.1 - 0.045 13.9 2.9 4.9 7.3 0.3 3.0 1 1 2 3 3 3 0 Dam-replacing HTH domain Arf PF00025.21 OWF37870.1 - 1.3e-62 210.3 0.1 1.5e-62 210.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF37870.1 - 4.4e-13 49.5 0.0 6.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF37870.1 - 1e-12 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF37870.1 - 5.5e-11 42.2 0.2 1.3e-10 41.0 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF37870.1 - 1.8e-06 27.5 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF37870.1 - 5.3e-06 25.8 0.1 0.0046 16.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF37870.1 - 0.00053 20.1 0.1 0.00092 19.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 OWF37870.1 - 0.045 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SpoOE-like PF09388.10 OWF37870.1 - 0.053 13.4 0.3 0.053 13.4 0.3 1.7 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein RNase_T PF00929.24 OWF37871.1 - 2.9e-23 83.2 0.0 5e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease zf-GRF PF06839.12 OWF37871.1 - 3.7e-10 39.7 3.4 1.3e-09 38.0 3.4 2.0 1 0 0 1 1 1 1 GRF zinc finger RNase_T PF00929.24 OWF37872.1 - 8.6e-08 32.9 0.3 1.2e-06 29.2 0.0 2.5 2 0 0 2 2 2 1 Exonuclease DUF3541 PF12060.8 OWF37872.1 - 0.031 14.0 0.6 0.07 12.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) DUF4355 PF14265.6 OWF37872.1 - 3.2 8.0 14.7 0.89 9.8 9.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Acetyltransf_1 PF00583.25 OWF37873.1 - 1.2e-13 51.4 0.0 1.8e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF37873.1 - 7e-05 22.8 0.0 0.00032 20.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF37873.1 - 0.00016 22.0 0.0 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF37873.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OWF37873.1 - 0.023 14.7 0.0 0.15 12.2 0.0 2.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4507 PF14964.6 OWF37874.1 - 8.9e-74 248.5 3.0 1e-73 248.4 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) APG9 PF04109.16 OWF37874.1 - 0.05 12.6 0.3 0.071 12.1 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg9 PAS PF00989.25 OWF37876.1 - 5.7e-05 23.1 14.7 5.7 7.0 0.0 8.8 2 2 6 9 9 9 3 PAS fold fn3_PAP PF17808.1 OWF37876.1 - 0.0042 17.2 38.9 9.9 6.3 0.1 11.5 1 1 8 12 12 12 3 Fn3-like domain from Purple Acid Phosphatase His_Phos_1 PF00300.22 OWF37876.1 - 0.022 14.5 35.7 1.4e+02 2.0 0.2 18.8 7 5 10 20 20 20 0 Histidine phosphatase superfamily (branch 1) Defensin_2 PF01097.18 OWF37876.1 - 0.14 12.1 16.5 59 3.7 0.1 8.8 6 0 0 6 6 6 0 Arthropod defensin Lig_chan-Glu_bd PF10613.9 OWF37877.1 - 1e-15 57.9 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF37877.1 - 1.1e-15 57.7 0.0 6.5e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 OWF37877.1 - 2.1e-15 56.8 1.8 5.5e-15 55.5 1.5 1.8 1 1 1 2 2 2 1 Ligand-gated ion channel Ras PF00071.22 OWF37878.1 - 6.9e-39 133.0 0.0 7.9e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF37878.1 - 1e-19 70.9 0.2 1.7e-19 70.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF37878.1 - 2e-07 30.6 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF37878.1 - 0.0024 18.0 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 OWF37878.1 - 0.0079 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 OWF37878.1 - 0.015 15.2 0.0 6.2 6.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Ank_2 PF12796.7 OWF37879.1 - 3.5e-20 72.4 0.1 2.3e-08 34.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF37879.1 - 5.6e-12 45.9 2.3 0.00033 21.2 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37879.1 - 5.4e-11 41.7 2.4 0.0015 18.9 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat SOCS_box PF07525.16 OWF37879.1 - 2.5e-09 37.4 1.1 6.5e-09 36.0 1.1 1.7 1 0 0 1 1 1 1 SOCS box Ank_5 PF13857.6 OWF37879.1 - 4.3e-09 36.5 2.2 0.00033 20.9 0.2 4.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF37879.1 - 4.6e-07 30.0 5.5 0.017 15.6 0.0 5.1 4 1 0 4 4 4 2 Ankyrin repeat Ribonuc_2-5A PF06479.12 OWF37880.1 - 4.5e-43 146.5 1.9 7.8e-43 145.7 1.9 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 OWF37880.1 - 4.3e-39 134.5 0.0 2e-38 132.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37880.1 - 3.5e-24 85.5 0.0 7.3e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 OWF37880.1 - 6.3e-11 42.3 0.0 5.1e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OWF37880.1 - 2.5e-09 36.6 1.8 0.33 10.9 0.0 5.1 5 0 0 5 5 5 3 PQQ enzyme repeat Pkinase_fungal PF17667.1 OWF37880.1 - 1.5e-06 27.3 0.0 7e-06 25.1 0.0 1.9 1 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OWF37880.1 - 0.0014 18.6 0.2 0.58 10.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OWF37880.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.6 OWF37880.1 - 0.0084 16.6 0.0 1.5 9.4 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain DUF1738 PF08401.11 OWF37880.1 - 0.099 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) MMM1 PF10296.9 OWF37881.1 - 2.1e-07 30.3 0.1 2.1e-07 30.3 0.1 3.1 3 1 1 4 4 4 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 OWF37881.1 - 0.0015 19.0 0.0 0.0054 17.2 0.0 2.0 1 0 0 1 1 1 1 PH domain DUF3456 PF11938.8 OWF37882.1 - 9e-45 153.0 6.3 1.4e-44 152.4 6.3 1.3 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP WD40 PF00400.32 OWF37883.1 - 8.5e-15 54.9 12.3 0.0012 19.6 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF37883.1 - 2.5e-07 30.9 2.3 0.33 11.3 0.0 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OWF37883.1 - 0.018 13.1 0.8 0.055 11.5 0.0 2.0 2 1 1 3 3 3 0 IKI3 family Syncollin PF15138.6 OWF37883.1 - 0.096 12.9 0.8 0.7 10.1 0.0 2.5 2 1 0 2 2 2 0 Syncollin PD40 PF07676.12 OWF37883.1 - 0.15 12.0 0.2 11 6.0 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Alpha_kinase PF02816.18 OWF37884.1 - 3.6e-61 206.5 0.1 8.9e-61 205.2 0.1 1.7 1 0 0 1 1 1 1 Alpha-kinase family RRM_1 PF00076.22 OWF37885.1 - 0.0012 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 OWF37886.1 - 0.011 14.0 11.6 0.013 13.8 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Fmp27_SW PF10305.9 OWF37886.1 - 0.1 13.3 2.8 0.57 10.9 0.7 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TALPID3 PF15324.6 OWF37886.1 - 0.41 8.3 10.9 0.51 7.9 10.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target ALMT PF11744.8 OWF37886.1 - 1.2 7.9 11.7 1.5 7.6 11.7 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter RRN3 PF05327.11 OWF37886.1 - 2.7 6.4 12.9 3.1 6.2 12.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CPSF100_C PF13299.6 OWF37886.1 - 2.8 8.1 12.6 1.3 9.2 10.4 1.6 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 OWF37886.1 - 3.5 5.6 16.2 4 5.4 16.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi zf-CHCC PF10276.9 OWF37890.1 - 3e-10 40.0 0.0 5.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger domain Cadherin PF00028.17 OWF37891.1 - 8.5e-07 29.3 0.4 0.0013 19.1 0.0 2.6 2 1 0 2 2 2 2 Cadherin domain CRIM PF16978.5 OWF37891.1 - 0.061 13.5 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain Spem1 PF15670.5 OWF37891.1 - 0.51 9.9 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 Cadherin PF00028.17 OWF37892.1 - 8.1e-07 29.4 2.5 0.0081 16.6 0.1 3.6 2 1 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.5 OWF37892.1 - 0.033 14.2 1.0 0.46 10.5 0.1 2.7 3 0 0 3 3 3 0 Cadherin-like Cadherin PF00028.17 OWF37893.1 - 0.00018 21.8 3.2 0.72 10.3 0.1 3.6 3 1 0 3 3 3 2 Cadherin domain FAM27 PF15832.5 OWF37893.1 - 0.0062 17.1 0.7 0.017 15.7 0.7 1.7 1 0 0 1 1 1 1 FAM27 D and E protein family Glycophorin_A PF01102.18 OWF37893.1 - 0.0074 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A DUF4051 PF13260.6 OWF37893.1 - 0.026 14.2 0.1 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) TMEM154 PF15102.6 OWF37893.1 - 0.038 13.9 0.3 0.038 13.9 0.3 2.7 2 1 1 3 3 3 0 TMEM154 protein family Cadherin_3 PF16184.5 OWF37893.1 - 0.062 13.3 0.5 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 Cadherin-like LapA_dom PF06305.11 OWF37893.1 - 0.35 10.7 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Baculo_11_kDa PF06143.11 OWF37893.1 - 1.3 8.6 3.6 12 5.6 0.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family FXR_C1 PF16096.5 OWF37893.1 - 7 6.9 7.2 0.92 9.8 2.1 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Roc PF08477.13 OWF37895.1 - 8.2e-13 48.6 0.0 6.6e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF37895.1 - 1.5e-10 41.2 0.3 8.1e-10 38.8 0.2 2.3 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Death PF00531.22 OWF37895.1 - 7.4e-08 32.5 0.0 0.00024 21.2 0.0 2.8 2 0 0 2 2 2 2 Death domain Arf PF00025.21 OWF37895.1 - 6.9e-05 22.4 0.1 0.022 14.2 0.0 3.2 3 0 0 3 3 3 1 ADP-ribosylation factor family Ras PF00071.22 OWF37895.1 - 0.00054 19.6 0.0 0.035 13.7 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_18 PF13238.6 OWF37895.1 - 0.0074 16.8 0.0 0.025 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF37895.1 - 0.017 15.4 0.0 0.067 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF37895.1 - 0.061 13.5 0.2 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OWF37895.1 - 0.084 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OWF37895.1 - 0.09 12.1 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 OWF37895.1 - 0.091 13.0 0.2 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OWF37895.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 NTPase Death PF00531.22 OWF37896.1 - 4.5e-08 33.1 0.0 4.6e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Death domain Arg_repressor PF01316.21 OWF37896.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Fibrinogen_C PF00147.18 OWF37897.1 - 3.6e-61 206.8 4.8 4.2e-61 206.6 4.8 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain I-set PF07679.16 OWF37898.1 - 1.1e-51 172.8 0.2 6.7e-12 45.3 0.0 4.7 5 0 0 5 5 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF37898.1 - 3.7e-49 165.2 7.4 1.5e-12 47.9 0.0 4.8 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 OWF37898.1 - 4.5e-37 126.2 0.7 7.9e-09 35.7 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 OWF37898.1 - 7.1e-33 112.6 2.4 4.6e-09 36.3 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain Collagen PF01391.18 OWF37898.1 - 3e-20 71.7 64.8 5.7e-08 32.4 23.5 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) LCCL PF03815.19 OWF37898.1 - 1.7e-15 56.9 2.1 7.5e-15 54.8 2.1 2.2 1 0 0 1 1 1 1 LCCL domain V-set PF07686.17 OWF37898.1 - 3.2e-14 53.0 7.0 0.012 15.7 0.1 6.5 4 3 1 5 5 5 3 Immunoglobulin V-set domain Ig_5 PF16681.5 OWF37898.1 - 1.8e-08 34.7 0.0 0.86 10.1 0.0 4.6 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 OWF37898.1 - 6.3e-08 32.8 0.0 0.41 10.9 0.0 5.0 5 1 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 OWF37898.1 - 1.7e-07 30.7 0.0 0.14 11.7 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin domain Izumo-Ig PF16706.5 OWF37898.1 - 9.8e-05 22.3 0.1 2.3 8.3 0.0 4.3 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF37898.1 - 0.00063 19.7 0.1 10 6.2 0.0 3.9 3 1 0 3 3 3 1 C17orf99 Ig domain C2-set PF05790.15 OWF37898.1 - 0.011 15.8 0.0 3.8 7.8 0.0 3.8 5 0 0 5 5 4 0 Immunoglobulin C2-set domain Receptor_2B4 PF11465.8 OWF37898.1 - 0.047 13.9 0.1 16 5.7 0.0 4.2 4 1 1 5 5 5 0 Natural killer cell receptor 2B4 C1-set PF07654.15 OWF37898.1 - 0.13 12.7 0.8 0.8 10.1 0.0 2.7 3 0 0 3 3 2 0 Immunoglobulin C1-set domain DUF3540 PF12059.8 OWF37899.1 - 7.2e-05 22.7 7.5 0.0037 17.1 1.7 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3540) DUF3552 PF12072.8 OWF37899.1 - 0.0057 16.1 2.6 0.024 14.1 2.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) Cas6 PF09559.10 OWF37899.1 - 0.031 14.2 0.5 1.8 8.5 0.2 2.1 1 1 1 2 2 2 0 Cas6 Crispr T7SS_ESX_EspC PF10824.8 OWF37899.1 - 0.76 10.3 5.4 2.9 8.4 2.4 2.4 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Metal_resist PF13801.6 OWF37899.1 - 0.97 9.6 14.1 0.43 10.8 8.3 2.1 1 1 1 2 2 2 0 Heavy-metal resistance Nup54 PF13874.6 OWF37899.1 - 1.6 8.8 11.6 2.4 8.2 3.4 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 EF-hand_7 PF13499.6 OWF37900.1 - 4.5e-10 39.8 0.4 0.00023 21.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37900.1 - 8.3e-10 37.8 1.0 0.00033 20.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF37900.1 - 1.4e-07 30.7 1.0 0.0026 17.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF37900.1 - 2.7e-07 30.3 0.2 0.026 14.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF37900.1 - 2.7e-07 29.6 3.8 0.0035 16.8 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 OWF37900.1 - 0.0067 16.3 0.1 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_3 PF09069.11 OWF37900.1 - 0.044 14.2 0.1 6.3 7.3 0.0 2.4 1 1 1 2 2 2 0 EF-hand EF-hand_7 PF13499.6 OWF37901.1 - 2.5e-09 37.5 1.6 0.00012 22.4 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37901.1 - 6.3e-09 35.1 2.8 0.0023 17.7 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF37901.1 - 3.1e-07 29.6 1.2 0.0034 16.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OWF37901.1 - 7.6e-07 28.2 3.3 0.018 14.5 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF37901.1 - 5.4e-06 26.1 0.2 0.093 12.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 OWF37901.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.9 OWF37901.1 - 0.0062 16.9 0.0 4.5 7.6 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 OWF37901.1 - 0.16 12.4 0.3 11 6.5 0.0 2.4 1 1 1 2 2 2 0 EF-hand Snapin_Pallidin PF14712.6 OWF37902.1 - 9e-22 77.3 5.7 9e-22 77.3 5.7 1.8 2 0 0 2 2 2 1 Snapin/Pallidin TCP PF03634.13 OWF37902.1 - 0.88 10.1 13.7 0.42 11.2 11.3 1.5 2 0 0 2 2 2 0 TCP family transcription factor Proteasome PF00227.26 OWF37903.1 - 3.2e-33 114.8 0.0 3.8e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit CH PF00307.31 OWF37904.1 - 3.1e-13 49.9 0.1 4.5e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Filamin PF00630.19 OWF37904.1 - 5.9e-11 43.1 0.0 1e-10 42.4 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat CAMSAP_CH PF11971.8 OWF37904.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain PBD PF00786.28 OWF37905.1 - 0.0001 22.6 0.1 0.00017 21.9 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain Thioredoxin PF00085.20 OWF37906.1 - 1.6e-10 40.8 0.0 4e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin DUF836 PF05768.14 OWF37906.1 - 1e-05 25.9 0.0 0.16 12.4 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OWF37906.1 - 0.00041 20.8 0.5 0.0022 18.4 0.3 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 OWF37906.1 - 0.0011 18.9 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 OWF37906.1 - 0.0061 16.5 0.0 0.66 9.9 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.6 OWF37906.1 - 0.011 15.7 0.1 0.036 14.1 0.1 1.8 2 0 0 2 2 2 0 Thioredoxin domain DUF832 PF05734.11 OWF37906.1 - 0.042 13.3 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) TraF PF13728.6 OWF37906.1 - 0.05 13.4 0.0 2.3 8.0 0.1 2.5 2 1 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OWF37906.1 - 0.46 10.8 5.6 1.7 8.9 1.8 3.4 3 1 0 3 3 3 0 Glutaredoxin 7tm_1 PF00001.21 OWF37907.1 - 3.2e-11 43.1 13.4 3.6e-11 42.9 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF37907.1 - 1.2e-08 35.1 4.5 1.5e-08 34.7 4.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF37907.1 - 0.0087 15.5 10.4 0.01 15.2 10.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PNTB_4TM PF12769.7 OWF37907.1 - 0.19 12.2 3.5 0.1 13.1 1.0 1.8 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch 7tm_1 PF00001.21 OWF37908.1 - 4.4e-15 55.7 12.3 5.4e-15 55.4 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF37908.1 - 1.8e-07 31.2 8.4 2.6e-07 30.6 8.4 1.2 1 0 0 1 1 1 1 Olfactory receptor PNTB_4TM PF12769.7 OWF37908.1 - 0.31 11.5 3.3 0.17 12.3 0.8 1.9 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch SNF PF00209.18 OWF37909.1 - 5.7e-23 81.4 28.3 3.9e-16 58.8 6.5 2.2 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family DUF1482 PF07358.11 OWF37910.1 - 0.00011 22.0 0.9 4 7.4 0.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF1482) Nitroreductase PF00881.24 OWF37910.1 - 0.16 12.0 0.6 32 4.5 0.0 2.7 1 1 2 3 3 3 0 Nitroreductase family DHFR_1 PF00186.19 OWF37912.1 - 4.6e-52 175.9 0.0 2.2e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Dihydrofolate reductase CARD PF00619.21 OWF37913.1 - 1.9e-06 27.8 0.6 4.4e-06 26.6 0.6 1.6 1 0 0 1 1 1 1 Caspase recruitment domain Neuralized PF07177.12 OWF37913.1 - 4.6e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Neuralized CARD_2 PF16739.5 OWF37913.1 - 5.9e-05 23.0 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain FtsK_gamma PF09397.10 OWF37914.1 - 0.074 12.9 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Ftsk gamma domain RNA_pol_Rpb2_6 PF00562.28 OWF37914.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 zf-C2H2 PF00096.26 OWF37915.1 - 2e-30 103.5 73.1 2e-06 27.9 0.4 9.6 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF37915.1 - 9.3e-29 97.6 67.0 0.00053 20.6 0.4 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 OWF37915.1 - 1.1e-20 73.4 50.0 0.0051 17.2 1.1 8.8 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OWF37915.1 - 2.7e-19 68.6 64.8 4e-08 33.3 0.2 9.9 12 0 0 12 12 11 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF37915.1 - 2.8e-12 46.6 38.1 0.001 19.3 1.0 8.7 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF37915.1 - 9.1e-06 25.5 62.7 0.14 12.2 1.0 8.8 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OWF37915.1 - 1.1e-05 25.7 49.5 0.18 12.1 1.6 9.5 6 3 4 10 10 10 4 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 OWF37915.1 - 0.00024 20.8 25.4 0.0026 17.5 3.2 7.3 7 0 0 7 7 7 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 OWF37915.1 - 0.047 14.4 19.1 1.7 9.4 1.2 6.0 4 2 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 OWF37915.1 - 0.071 13.6 39.8 0.21 12.0 0.0 7.7 4 2 1 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 OWF37915.1 - 0.15 11.9 0.1 0.15 11.9 0.1 7.5 7 0 0 7 7 7 0 zinc-finger C2H2-type zf_C2H2_10 PF18414.1 OWF37915.1 - 1.9 8.1 9.8 0.52 9.9 0.2 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger BolA PF01722.18 OWF37915.1 - 2.1 8.7 4.0 30 5.0 0.1 3.8 4 0 0 4 4 3 0 BolA-like protein Desulfoferrod_N PF06397.12 OWF37915.1 - 3.1 7.5 14.7 4.1 7.1 0.3 4.3 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain APOBEC1 PF18769.1 OWF37917.1 - 0.023 14.9 0.5 0.072 13.3 0.5 1.8 1 0 0 1 1 1 0 APOBEC1 Peptidase_M41 PF01434.18 OWF37918.1 - 2.8e-50 170.8 1.7 4.8e-50 170.1 1.7 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OWF37918.1 - 8.4e-44 149.2 0.0 2.9e-43 147.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF37918.1 - 6.2e-13 48.3 0.1 1.6e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OWF37918.1 - 8e-09 35.8 0.0 2.4e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 OWF37918.1 - 0.00093 19.5 1.4 0.14 12.4 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.14 OWF37918.1 - 0.0018 18.3 0.0 0.011 15.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF1514 PF07438.11 OWF37918.1 - 0.0024 17.7 0.3 0.0073 16.2 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1514) TIP49 PF06068.13 OWF37918.1 - 0.0034 16.7 0.1 0.0077 15.5 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OWF37918.1 - 0.0036 17.4 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OWF37918.1 - 0.0041 16.9 0.0 0.023 14.5 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OWF37918.1 - 0.015 15.7 0.6 0.29 11.5 0.1 2.9 2 1 1 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 OWF37918.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 OWF37918.1 - 0.03 14.8 0.1 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OWF37918.1 - 0.04 13.3 0.2 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OWF37918.1 - 0.066 13.3 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF37918.1 - 0.1 12.8 0.0 0.56 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OWF37918.1 - 0.13 12.8 0.1 0.81 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OWF37918.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain EF-hand_8 PF13833.6 OWF37919.1 - 0.00034 20.4 2.6 0.019 14.8 0.6 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF37919.1 - 0.0012 18.7 3.6 0.16 12.0 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OWF37919.1 - 0.0039 17.6 2.0 0.0077 16.7 1.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF37919.1 - 0.018 14.6 5.4 0.12 12.0 0.4 2.8 3 0 0 3 3 3 0 EF hand EF-hand_10 PF14788.6 OWF37919.1 - 0.08 12.8 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 EF hand Zona_pellucida PF00100.23 OWF37920.1 - 1.5e-24 87.2 3.7 1.8e-24 86.9 3.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain GCIP PF13324.6 OWF37921.1 - 2.6e-60 204.3 0.3 3.8e-60 203.7 0.3 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting dsDNA_bind PF01984.20 OWF37922.1 - 4.6e-38 129.9 6.3 5.2e-38 129.7 6.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain FeoC PF09012.10 OWF37922.1 - 0.07 13.2 0.3 0.19 11.8 0.3 1.8 1 1 0 1 1 1 0 FeoC like transcriptional regulator SieB PF14163.6 OWF37922.1 - 0.2 11.1 0.9 0.27 10.7 0.9 1.3 1 1 0 1 1 1 0 Super-infection exclusion protein B TRAM_LAG1_CLN8 PF03798.16 OWF37923.1 - 0.0064 16.2 12.9 0.011 15.4 12.9 1.4 1 0 0 1 1 1 1 TLC domain PHO4 PF01384.20 OWF37923.1 - 0.33 9.9 3.0 2.2 7.2 1.1 2.2 2 0 0 2 2 2 0 Phosphate transporter family GST_C PF00043.25 OWF37924.1 - 2.5e-09 37.2 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF37924.1 - 1.3e-08 35.0 0.0 5.9e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF37924.1 - 2.5e-08 34.2 0.1 1e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF37924.1 - 1.9e-07 31.2 0.1 3.7e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF37924.1 - 0.00019 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF37924.1 - 0.00027 21.2 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF37924.1 - 0.028 15.1 0.0 0.29 11.9 0.0 2.5 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain adh_short PF00106.25 OWF37925.1 - 1.9e-31 109.0 0.0 3.3e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF37925.1 - 3.1e-27 95.6 0.0 4.3e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF37925.1 - 2.5e-05 24.3 0.1 5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OWF37925.1 - 0.043 13.1 0.1 0.08 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CobN-Mg_chel PF02514.16 OWF37925.1 - 0.064 11.0 0.0 0.085 10.6 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase AdoHcyase_NAD PF00670.21 OWF37925.1 - 0.28 11.2 2.5 0.5 10.4 2.5 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 7tm_2 PF00002.24 OWF37926.1 - 6.4e-32 110.8 18.3 8e-32 110.5 18.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF5378 PF17349.2 OWF37926.1 - 1.1 8.5 10.2 0.11 11.8 4.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5378) potato_inhibit PF00280.18 OWF37927.1 - 5.4e-07 30.2 70.4 78 4.1 0.2 18.8 1 1 23 24 24 24 4 Potato inhibitor I family Disaggr_assoc PF08480.10 OWF37927.1 - 0.0043 17.0 47.7 37 4.1 0.2 11.0 1 1 15 18 18 18 18 Disaggregatase related DUF823 PF05689.11 OWF37928.1 - 0.00086 19.1 2.6 0.34 10.6 0.2 2.3 1 1 1 2 2 2 2 Salmonella repeat of unknown function (DUF823) Rimk_N PF18030.1 OWF37928.1 - 0.0061 16.9 0.4 3 8.3 0.1 2.7 1 1 1 2 2 2 2 RimK PreATP-grasp domain B12D PF06522.11 OWF37928.1 - 0.13 12.0 9.5 61 3.5 0.1 5.9 1 1 6 7 7 7 0 NADH-ubiquinone reductase complex 1 MLRQ subunit potato_inhibit PF00280.18 OWF37928.1 - 0.47 11.2 3.5 11 6.7 0.2 3.2 2 1 0 3 3 3 0 Potato inhibitor I family B12D PF06522.11 OWF37930.1 - 0.0055 16.5 6.1 6.4 6.7 0.0 5.2 2 1 2 5 5 5 2 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF5104 PF17117.5 OWF37930.1 - 0.26 11.7 2.0 22 5.6 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5104) potato_inhibit PF00280.18 OWF37930.1 - 0.4 11.4 3.8 26 5.6 0.1 3.7 1 1 1 4 4 4 0 Potato inhibitor I family SBF PF01758.16 OWF37931.1 - 1.4e-26 93.4 20.1 1.4e-26 93.4 20.1 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4234 PF14018.6 OWF37931.1 - 0.077 13.1 5.3 0.62 10.2 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) SBF PF01758.16 OWF37932.1 - 3.2e-38 131.4 11.1 3.2e-38 131.4 11.1 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF PF01758.16 OWF37933.1 - 1.8e-37 128.9 10.6 1.8e-37 128.9 10.6 2.3 1 1 1 2 2 2 1 Sodium Bile acid symporter family CUB PF00431.20 OWF37934.1 - 2.3e-15 56.9 0.0 5.3e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 OWF37934.1 - 3.5e-08 33.5 11.0 7e-08 32.6 11.0 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Amnionless PF14828.6 OWF37934.1 - 0.0012 17.7 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Amnionless FixQ PF05545.11 OWF37934.1 - 0.72 9.9 4.2 2 8.4 4.2 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Syndecan PF01034.20 OWF37934.1 - 0.73 9.8 4.0 1.8 8.5 4.0 1.6 1 0 0 1 1 1 0 Syndecan domain CUB PF00431.20 OWF37936.1 - 1.4e-12 47.9 0.0 2.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 OWF37936.1 - 8.9e-09 35.4 5.7 8.9e-09 35.4 5.7 2.0 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A RhoGEF PF00621.20 OWF37937.1 - 1.6e-31 110.0 4.7 1.6e-31 110.0 4.7 2.7 2 1 1 3 3 3 1 RhoGEF domain PH PF00169.29 OWF37937.1 - 6.1e-06 26.7 0.3 3.4e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 OWF37937.1 - 0.00047 20.2 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 OWF37937.1 - 0.0021 18.3 0.2 0.025 14.8 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain zf-H2C2_2 PF13465.6 OWF37938.1 - 1.1e-18 66.7 67.6 1.6e-05 25.1 2.5 10.3 10 0 0 10 10 10 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF37938.1 - 5.2e-16 58.1 67.8 1e-06 28.4 0.3 9.3 9 0 0 9 9 9 7 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF37938.1 - 1.5e-15 56.6 73.9 0.0042 17.5 1.4 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF37938.1 - 1.4e-14 53.5 67.4 0.0019 18.9 1.2 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger BTB PF00651.31 OWF37938.1 - 4.9e-14 52.5 2.4 1e-13 51.5 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain zf_C2H2_ZHX PF18387.1 OWF37938.1 - 0.074 12.7 0.0 0.074 12.7 0.0 6.3 3 2 4 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain AT_hook PF02178.19 OWF37938.1 - 0.31 11.1 7.5 0.98 9.5 7.5 1.9 1 0 0 1 1 1 0 AT hook motif YyzF PF14116.6 OWF37938.1 - 8.6 6.5 18.1 6.9 6.8 0.1 6.3 6 1 1 7 7 7 0 YyzF-like protein PX PF00787.24 OWF37939.1 - 2.5e-14 53.2 0.8 3.7e-14 52.7 0.8 1.3 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 OWF37939.1 - 3.1e-07 30.6 0.0 5.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Ank_2 PF12796.7 OWF37940.1 - 2.5e-29 101.7 1.6 2.1e-14 53.8 0.5 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF37940.1 - 1.2e-27 95.9 2.7 9.1e-12 45.3 0.1 6.1 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37940.1 - 1.4e-25 89.0 5.2 7.6e-08 32.5 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF37940.1 - 8.4e-21 73.4 8.0 8.1e-05 22.9 0.4 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OWF37940.1 - 1.1e-19 68.4 5.2 0.002 18.4 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Peptidase_M22 PF00814.25 OWF37941.1 - 1.2e-87 294.1 0.0 1.4e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OWF37941.1 - 0.00026 20.8 0.0 0.0087 15.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus Na_Pi_cotrans PF02690.15 OWF37943.1 - 1e-34 119.7 23.8 1.2e-22 80.5 6.7 3.2 3 1 0 3 3 3 2 Na+/Pi-cotransporter DUF4407 PF14362.6 OWF37943.1 - 1 8.6 4.2 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Na_Pi_cotrans PF02690.15 OWF37944.1 - 6.6e-16 58.7 26.2 3.7e-09 36.8 17.8 3.3 2 1 0 2 2 2 2 Na+/Pi-cotransporter Cadherin_C_2 PF16492.5 OWF37944.1 - 0.23 12.2 1.6 0.97 10.2 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Phospholip_A2_3 PF09056.11 OWF37945.1 - 4.4e-06 27.3 6.0 7.7e-06 26.5 6.0 1.4 1 1 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 OWF37945.1 - 0.00013 22.0 2.7 0.00017 21.6 2.7 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) MDD_C PF18376.1 OWF37946.1 - 3.7e-75 251.8 0.0 5.4e-75 251.2 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OWF37946.1 - 1.5e-06 28.4 3.3 3.4e-06 27.2 3.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Rsm22 PF09243.10 OWF37947.1 - 2.2e-54 184.6 0.1 3.3e-54 184.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ank_2 PF12796.7 OWF37948.1 - 6.5e-52 174.1 1.3 3e-16 59.8 0.1 5.2 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF37948.1 - 2.7e-49 164.9 5.9 8.2e-08 32.7 0.1 8.5 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF37948.1 - 2.3e-39 132.9 9.0 7.1e-08 32.6 0.2 7.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF37948.1 - 1.1e-36 120.6 3.7 0.0012 19.2 0.0 10.7 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 OWF37948.1 - 4.2e-34 115.5 11.5 0.0014 19.0 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat SAM_1 PF00536.30 OWF37948.1 - 1.7e-09 38.0 0.1 2.9e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF37948.1 - 4.7e-08 33.0 0.3 9.4e-08 32.1 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 OWF37948.1 - 0.07 13.2 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 IGR protein motif AIG2_2 PF13772.6 OWF37949.1 - 2.1e-19 69.7 0.0 2.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 OWF37949.1 - 8.2e-08 32.9 0.0 1.1e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like A_amylase_inhib PF01356.19 OWF37949.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase inhibitor AIG2_2 PF13772.6 OWF37950.1 - 1.2e-14 54.5 0.0 1.9e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 OWF37950.1 - 0.00026 21.6 0.1 0.00046 20.8 0.0 1.5 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like HSBP1 PF06825.12 OWF37951.1 - 8.5e-21 73.6 9.7 6.4e-20 70.7 9.7 1.9 1 1 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 OWF37951.1 - 0.0029 17.6 0.8 0.0034 17.4 0.8 1.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 OWF37951.1 - 0.013 15.8 0.7 0.016 15.5 0.7 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_min_cap2 PF06152.11 OWF37951.1 - 0.014 14.3 0.4 0.015 14.3 0.4 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF1664 PF07889.12 OWF37951.1 - 0.03 14.4 0.3 0.032 14.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 OWF37951.1 - 0.032 13.6 0.1 0.034 13.5 0.1 1.0 1 0 0 1 1 1 0 FAM76 protein CorA PF01544.18 OWF37951.1 - 0.034 13.4 0.2 0.037 13.3 0.2 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SseC PF04888.12 OWF37951.1 - 0.041 13.5 1.5 0.046 13.3 1.5 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF5446 PF17522.2 OWF37951.1 - 0.042 14.0 0.1 0.051 13.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5446) CLZ PF16526.5 OWF37951.1 - 0.046 14.1 0.3 0.084 13.2 0.3 1.5 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SCF PF02404.15 OWF37951.1 - 0.05 12.9 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor Pept_S41_N PF18294.1 OWF37951.1 - 0.052 13.5 0.2 0.097 12.7 0.2 1.4 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain ANAPC4 PF12896.7 OWF37951.1 - 0.057 12.9 0.1 0.06 12.8 0.1 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF4332 PF14229.6 OWF37951.1 - 0.07 13.4 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Hemagglutinin PF00509.18 OWF37951.1 - 0.1 11.0 0.6 0.12 10.8 0.6 1.0 1 0 0 1 1 1 0 Haemagglutinin DUF5601 PF18151.1 OWF37951.1 - 0.13 12.6 1.0 0.24 11.7 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1604 PF07713.13 OWF37952.1 - 4e-31 106.7 1.0 4e-31 106.7 1.0 3.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OWF37952.1 - 8.2e-07 28.8 0.4 2.4e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OWF37952.1 - 0.085 13.0 0.1 0.085 13.0 0.1 2.8 2 0 0 2 2 2 0 G-patch domain CSRNP_N PF16019.5 OWF37952.1 - 0.97 9.3 19.0 0.094 12.6 14.0 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus SH2 PF00017.24 OWF37953.1 - 8.3e-14 51.5 0.1 3.1e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 SH2 domain SOCS_box PF07525.16 OWF37953.1 - 2.7e-08 34.0 0.1 6.2e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 SOCS box LCAT PF02450.15 OWF37954.1 - 1.1e-72 245.3 3.8 2.2e-71 241.1 3.8 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 OWF37954.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 OWF37954.1 - 0.0029 17.0 0.1 0.81 9.0 0.1 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 OWF37954.1 - 0.004 17.0 0.0 0.0059 16.5 0.0 1.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF900 PF05990.12 OWF37954.1 - 0.0048 16.4 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 OWF37954.1 - 0.0059 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OWF37954.1 - 0.013 15.2 0.1 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_1 PF00561.20 OWF37954.1 - 0.1 12.3 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold CAP PF00188.26 OWF37955.1 - 1.6e-24 87.1 5.4 2.3e-24 86.6 5.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family AOC_like PF18678.1 OWF37955.1 - 0.026 14.1 0.5 0.29 10.8 0.1 2.1 2 0 0 2 2 2 0 Allene oxide cyclase barrel like domain Lipocalin_2 PF08212.12 OWF37956.1 - 9.6e-09 35.3 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF37956.1 - 0.058 13.6 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Sec5 PF15469.6 OWF37957.1 - 3.9e-45 154.0 1.0 1.1e-44 152.5 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.24 OWF37957.1 - 2.2e-08 34.1 0.4 5.2e-08 32.9 0.4 1.7 1 0 0 1 1 1 1 IPT/TIG domain DUF761 PF05553.11 OWF37957.1 - 0.12 12.0 0.3 0.34 10.5 0.3 1.8 1 0 0 1 1 1 0 Cotton fibre expressed protein Ldl_recept_a PF00057.18 OWF37958.1 - 4.7e-11 42.7 6.9 8.5e-11 41.9 6.9 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A stn_TNFRSF12A PF12191.8 OWF37958.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Stevor PF17410.2 OWF37958.1 - 0.045 13.3 0.1 0.096 12.2 0.0 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF4342 PF14242.6 OWF37958.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Adeno_E3_CR2 PF02439.15 OWF37958.1 - 0.067 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OWF37958.1 - 0.085 13.8 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.7 OWF37959.1 - 1.6e-10 40.7 0.0 3.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF37959.1 - 6.1e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain DUF3506 PF12014.8 OWF37959.1 - 2.5e-06 27.6 0.0 0.00075 19.5 0.0 3.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3506) Sulfotransfer_2 PF03567.14 OWF37961.1 - 1.5e-23 84.0 0.5 9.6e-20 71.6 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF37962.1 - 2.8e-24 86.4 1.5 1.2e-20 74.6 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family OrgA_MxiK PF09482.10 OWF37962.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Mab-21 PF03281.14 OWF37963.1 - 4.4e-33 114.8 0.0 7.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_17 PF13431.6 OWF37963.1 - 0.45 11.0 1.7 18 6.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat WBP-1 PF11669.8 OWF37964.1 - 2.8e-06 27.9 8.0 2.8e-06 27.9 8.0 1.7 1 1 1 2 2 2 1 WW domain-binding protein 1 Shisa PF13908.6 OWF37964.1 - 0.017 15.4 3.9 0.017 15.4 3.9 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.11 OWF37964.1 - 0.27 11.2 4.2 0.49 10.4 4.2 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein TPT PF03151.16 OWF37965.1 - 8.7e-18 64.7 14.8 1e-17 64.4 14.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OWF37965.1 - 0.5 10.5 28.4 0.34 11.1 13.7 2.9 2 1 1 3 3 3 0 EamA-like transporter family C2-C2_1 PF11618.8 OWF37966.1 - 3.2e-72 241.2 0.2 2.5e-53 179.9 0.0 4.7 4 0 0 4 4 4 4 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 OWF37966.1 - 4.3e-57 192.6 0.0 1.7e-56 190.6 0.0 2.1 1 0 0 1 1 1 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 OWF37966.1 - 1.5e-07 31.6 0.2 1.7e-06 28.3 0.0 2.8 3 0 0 3 3 3 1 C2 domain HTH_19 PF12844.7 OWF37966.1 - 0.059 13.4 2.9 0.071 13.1 0.5 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain kleA_kleC PF17383.2 OWF37966.1 - 0.38 11.1 3.5 2.8 8.4 3.5 2.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Mab-21 PF03281.14 OWF37967.1 - 2.9e-18 66.2 0.1 5.5e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 Mab-21 protein TPR_8 PF13181.6 OWF37967.1 - 0.0017 18.5 3.1 0.12 12.7 0.6 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF37967.1 - 0.0042 17.1 0.5 0.021 14.9 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF37967.1 - 0.0071 16.1 2.5 0.015 15.1 0.4 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Longin PF13774.6 OWF37967.1 - 0.054 13.5 0.5 0.12 12.5 0.5 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain TPR_12 PF13424.6 OWF37967.1 - 0.076 13.3 0.2 6.6 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DERM PF14704.6 OWF37968.1 - 6.4e-38 130.6 12.1 7.7e-38 130.3 12.1 1.0 1 0 0 1 1 1 1 Dermatopontin Cofilin_ADF PF00241.20 OWF37969.1 - 8.7e-22 77.2 0.4 9.7e-22 77.0 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CTP_transf_3 PF02348.19 OWF37969.1 - 0.12 12.3 0.2 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Cytidylyltransferase TDP43_N PF18694.1 OWF37970.1 - 2e-31 107.7 0.0 3.4e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 OWF37970.1 - 1.1e-20 73.2 0.1 3.2e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OWF37970.1 - 8.5e-06 25.7 0.0 0.14 12.2 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 OWF37970.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 RL domain Myosin_N PF02736.19 OWF37971.1 - 0.00026 20.7 43.1 0.061 13.2 1.2 7.4 3 2 6 9 9 9 5 Myosin N-terminal SH3-like domain Paramecium_SA PF01508.16 OWF37971.1 - 0.0011 19.3 28.3 0.16 12.4 16.7 3.0 1 1 1 2 2 2 2 Paramecium surface antigen domain NfeD PF01957.18 OWF37971.1 - 0.028 14.8 7.2 1.2 9.5 0.5 2.9 1 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding ADAM17_MPD PF16698.5 OWF37971.1 - 0.38 11.2 23.9 32 5.0 2.5 4.2 1 1 1 2 2 2 0 Membrane-proximal domain, switch, for ADAM17 Profilin PF00235.19 OWF37971.1 - 0.54 10.5 12.5 1.4e+02 2.7 12.4 3.0 1 1 0 1 1 1 0 Profilin ID PF18543.1 OWF37971.1 - 0.67 10.0 25.1 1.8 8.6 0.7 5.6 1 1 6 7 7 7 0 Intracellular delivery domain RsgI_N PF12791.7 OWF37971.1 - 1.6 8.7 19.0 39 4.3 0.2 6.6 2 2 6 9 9 9 0 Anti-sigma factor N-terminus OGG_N PF07934.12 OWF37971.1 - 1.8 8.7 4.5 22 5.2 4.5 2.1 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain DUF4768 PF15989.5 OWF37971.1 - 3.2 7.8 9.9 26 4.9 0.4 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4768) adh_short PF00106.25 OWF37972.1 - 5.2e-31 107.6 0.5 9.3e-31 106.8 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF37972.1 - 3.6e-28 98.7 0.1 5.8e-28 98.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF37972.1 - 3.4e-09 36.9 0.1 7.1e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 OWF37972.1 - 0.0073 16.4 0.3 0.013 15.5 0.3 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 OWF37972.1 - 0.028 13.8 0.2 0.062 12.6 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CobN-Mg_chel PF02514.16 OWF37972.1 - 0.21 9.3 0.0 0.25 9.0 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Kelch_1 PF01344.25 OWF37973.1 - 1.6e-27 94.8 0.2 8.2e-09 34.9 0.0 6.3 5 1 0 5 5 5 5 Kelch motif BTB PF00651.31 OWF37973.1 - 1.9e-26 92.5 0.4 4e-26 91.4 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF37973.1 - 8.2e-26 90.1 0.4 7.4e-25 87.0 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 OWF37973.1 - 3.5e-22 77.9 0.1 0.00015 21.9 0.0 5.7 3 1 2 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OWF37973.1 - 5e-17 61.1 2.5 4.7e-05 23.2 0.0 5.8 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OWF37973.1 - 1.5e-13 50.5 0.0 0.00056 19.9 0.0 5.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF37973.1 - 2.6e-13 49.9 0.0 0.0055 17.0 0.0 6.3 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF37973.1 - 4.1e-09 36.2 2.1 0.15 12.0 0.0 6.0 7 0 0 7 7 7 2 Kelch motif DUF3342 PF11822.8 OWF37973.1 - 0.01 16.0 0.1 0.038 14.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) RAG2 PF03089.14 OWF37973.1 - 0.032 13.2 0.0 5.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Recombination activating protein 2 MARVEL PF01284.23 OWF37974.1 - 1.1e-10 41.7 13.9 1.6e-10 41.2 13.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF5336 PF17270.2 OWF37974.1 - 0.12 12.0 4.1 0.17 11.5 0.0 2.2 1 1 2 3 3 3 0 Family of unknown function (DUF5336) Na_K-ATPase PF00287.18 OWF37974.1 - 0.15 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain DUF2177 PF09945.9 OWF37974.1 - 0.83 9.7 10.5 0.18 11.9 3.9 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2177) DUF4231 PF14015.6 OWF37974.1 - 1.3 9.5 6.0 1 9.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TIR_2 PF13676.6 OWF37976.1 - 2.2e-14 54.1 0.0 9.2e-12 45.6 0.0 2.6 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 OWF37976.1 - 9.5e-13 48.3 0.7 1.9e-12 47.3 0.7 1.5 1 0 0 1 1 1 1 TIR domain TIR-like PF10137.9 OWF37976.1 - 0.033 14.1 0.1 0.092 12.7 0.1 1.7 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain NHL PF01436.21 OWF37976.1 - 0.071 13.2 0.0 3.7 7.8 0.0 2.6 2 0 0 2 2 2 0 NHL repeat DUF5605 PF18310.1 OWF37976.1 - 0.14 12.1 0.2 0.76 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) Peptidase_M17 PF00883.21 OWF37977.1 - 1.8e-95 319.9 0.5 2.2e-95 319.5 0.5 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 OWF37977.1 - 1.3e-24 86.7 0.3 3.5e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 TLD PF07534.16 OWF37979.1 - 1.9e-36 125.4 1.4 3e-36 124.7 1.4 1.3 1 0 0 1 1 1 1 TLD CEP76-C2 PF15627.6 OWF37980.1 - 5.9e-54 181.9 0.0 1.3e-53 180.8 0.0 1.6 1 0 0 1 1 1 1 CEP76 C2 domain Methyltransf_21 PF05050.12 OWF37981.1 - 2.8e-11 43.7 0.1 5.1e-11 42.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 OWF37981.1 - 0.13 11.5 0.6 1.7 7.9 0.6 2.2 1 1 0 1 1 1 0 Vibrio cholerae RfbT protein Syja_N PF02383.18 OWF37982.1 - 1.1e-90 304.2 1.1 1.4e-90 303.8 1.1 1.1 1 0 0 1 1 1 1 SacI homology domain PBECR3 PF18812.1 OWF37982.1 - 0.56 10.2 2.3 2.5 8.1 0.3 2.5 2 1 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 DIX PF00778.17 OWF37983.1 - 0.0048 16.7 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 DIX domain Pkinase PF00069.25 OWF37984.1 - 6.8e-60 202.7 0.0 1.1e-59 202.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF37984.1 - 7.2e-46 156.6 0.0 1.3e-45 155.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF37984.1 - 0.017 14.5 0.1 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF37984.1 - 0.08 11.7 0.3 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase HECT PF00632.25 OWF37985.1 - 1.1e-97 327.2 0.2 1.5e-97 326.9 0.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OWF37985.1 - 7.7e-48 160.2 25.2 2.3e-13 50.0 3.0 4.8 4 0 0 4 4 4 4 WW domain C2 PF00168.30 OWF37985.1 - 7.4e-13 48.7 0.0 2.1e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain PIN_6 PF17146.4 OWF37986.1 - 1.2e-35 121.9 0.2 9.5e-35 119.0 0.0 2.5 3 0 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 OWF37986.1 - 5.5e-28 96.9 0.3 1.2e-27 95.8 0.3 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like WRNPLPNID PF15017.6 OWF37986.1 - 0.23 12.4 26.6 11 7.0 26.6 2.6 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box PX PF00787.24 OWF37987.1 - 1.8e-06 27.9 0.5 5.1e-06 26.5 0.5 1.8 1 0 0 1 1 1 1 PX domain MAPKK1_Int PF08923.10 OWF37987.1 - 0.21 11.4 0.4 12 5.8 0.1 2.3 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting Kelch_4 PF13418.6 OWF37988.1 - 7.6e-35 118.7 0.2 1.1e-08 35.0 0.0 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF37988.1 - 6.8e-30 102.8 1.9 9e-07 29.0 0.0 7.6 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF37988.1 - 1.1e-28 98.5 1.7 1.4e-06 28.4 0.0 6.2 3 1 3 6 6 6 4 Kelch motif Kelch_5 PF13854.6 OWF37988.1 - 2.6e-24 84.7 0.4 8.2e-08 32.1 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OWF37988.1 - 3.4e-16 58.5 10.7 0.00081 19.3 0.0 7.1 6 2 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OWF37988.1 - 1.1e-12 47.3 6.1 6.1e-07 28.9 0.1 6.5 6 1 0 6 6 6 2 Kelch motif BNR_2 PF13088.6 OWF37988.1 - 0.082 12.2 0.0 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 BNR repeat-like domain ADAM_spacer1 PF05986.14 OWF37988.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Adeno_terminal PF02459.15 OWF37988.1 - 4 5.7 9.4 6.8 5.0 9.4 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Brr6_like_C_C PF10104.9 OWF37989.1 - 1.3 8.8 5.0 22 4.8 3.9 2.3 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain SAM_1 PF00536.30 OWF37989.1 - 2.1 8.9 5.5 28 5.2 0.1 3.4 1 1 3 4 4 4 0 SAM domain (Sterile alpha motif) Colicin_M PF14859.6 OWF37989.1 - 7.6 5.6 18.7 14 4.7 2.8 3.1 1 1 2 3 3 3 0 Colicin M Alpha_kinase PF02816.18 OWF37990.1 - 8.4e-29 101.0 0.1 1.1e-28 100.7 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 OWF37991.1 - 7.3e-23 81.6 2.3 1.1e-22 81.0 2.3 1.3 1 0 0 1 1 1 1 Alpha-kinase family Pecanex_C PF05041.15 OWF37991.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Alpha_kinase PF02816.18 OWF37992.1 - 7.9e-23 81.5 0.2 1.1e-22 81.0 0.2 1.3 1 0 0 1 1 1 1 Alpha-kinase family DUF1011 PF06237.12 OWF37993.1 - 2.7e-36 123.8 8.5 2.7e-36 123.8 8.5 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1011) Alpha_kinase PF02816.18 OWF37994.1 - 1.2e-21 77.7 4.0 1.7e-21 77.1 2.1 1.9 1 1 1 2 2 2 1 Alpha-kinase family UPF0113_N PF17833.1 OWF37994.1 - 4.9 7.8 6.3 82 3.9 6.3 2.3 1 1 0 1 1 1 0 UPF0113 Pre-PUA domain Alpha_kinase PF02816.18 OWF37995.1 - 1.9e-28 99.8 0.1 2.6e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF5389 PF17364.2 OWF37996.1 - 0.78 9.8 4.9 1.9 8.6 5.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5389) Stevor PF17410.2 OWF37996.1 - 1 8.9 6.6 1.4 8.4 6.6 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3792 PF12670.7 OWF37996.1 - 4.3 7.5 13.9 0.84 9.8 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) CD225 PF04505.12 OWF37997.1 - 9.9e-17 60.8 2.7 1.3e-16 60.4 2.7 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Stevor PF17410.2 OWF37998.1 - 1.2 8.6 7.1 1.5 8.3 7.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3671 PF12420.8 OWF37998.1 - 8.4 6.5 7.9 35 4.5 7.9 1.9 1 1 0 1 1 1 0 Protein of unknown function CD225 PF04505.12 OWF37999.1 - 5.8e-17 61.6 3.4 7.2e-17 61.3 3.4 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein CD225 PF04505.12 OWF38000.1 - 8.9e-11 41.8 1.0 1.3e-10 41.3 1.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein CD225 PF04505.12 OWF38001.1 - 8.8e-20 70.6 2.5 1.2e-19 70.1 2.5 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein FtsX PF02687.21 OWF38001.1 - 0.64 10.5 5.2 0.93 10.0 5.2 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF4190 PF13828.6 OWF38001.1 - 1.6 8.5 5.3 3.7 7.4 5.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) Rubis-subs-bind PF09273.11 OWF38002.1 - 0.19 12.4 2.1 0.14 12.8 0.6 1.5 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding DUF4124 PF13511.6 OWF38003.1 - 0.031 14.6 3.3 5.2 7.5 0.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) zf-C2H2_jaz PF12171.8 OWF38003.1 - 3.5 8.0 24.9 0.061 13.6 3.8 4.3 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NIPSNAP PF07978.13 OWF38004.1 - 2.2e-07 31.0 0.0 0.00015 21.9 0.0 2.9 3 0 0 3 3 3 2 NIPSNAP BROMI PF14961.6 OWF38005.1 - 0 1477.0 10.2 0 1476.8 10.2 1.0 1 0 0 1 1 1 1 Broad-minded protein mRNA_decap_C PF16741.5 OWF38005.1 - 0.055 12.8 0.0 3 7.2 0.0 2.8 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus SKA2 PF16740.5 OWF38005.1 - 0.12 12.2 0.0 2.2 8.1 0.0 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 PBP PF01161.20 OWF38006.1 - 9.3e-12 45.4 0.0 1.8e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein bZIP_2 PF07716.15 OWF38007.1 - 3.1e-15 56.0 12.1 4.7e-15 55.4 12.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF38007.1 - 2.5e-06 27.5 10.7 4.6e-06 26.6 10.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor GAS PF13851.6 OWF38007.1 - 0.00064 19.1 4.6 0.00081 18.8 4.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Paramyxo_NS_C PF02725.14 OWF38007.1 - 0.09 12.9 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 Non-structural protein C Tho2 PF11262.8 OWF38007.1 - 0.11 11.6 5.7 0.14 11.3 5.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF5320 PF17253.2 OWF38007.1 - 0.15 13.2 0.8 0.24 12.5 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) TMF_DNA_bd PF12329.8 OWF38007.1 - 0.2 11.7 10.9 0.58 10.2 7.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 OWF38008.1 - 3.1e-15 56.0 10.3 3.1e-15 56.0 10.3 1.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF38008.1 - 2.1e-05 24.5 8.3 2.1e-05 24.5 8.3 1.6 1 1 0 1 1 1 1 bZIP transcription factor ORC6 PF05460.13 OWF38008.1 - 0.0056 16.0 8.6 0.0084 15.4 8.6 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Hema_stalk PF08720.10 OWF38008.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk TMF_DNA_bd PF12329.8 OWF38008.1 - 3.2 7.8 11.0 5.9 7.0 11.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MAP1B_neuraxin PF00414.17 OWF38009.1 - 1.2e-32 110.1 319.3 4.3 7.0 0.6 47.6 47 0 0 47 47 47 47 Neuraxin and MAP1B repeat UCH PF00443.29 OWF38010.1 - 2.2e-45 155.2 0.0 3.9e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF38010.1 - 3.1e-09 36.9 0.0 1.1e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Lebercilin PF15619.6 OWF38010.1 - 0.091 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease adh_short PF00106.25 OWF38011.1 - 2.3e-24 85.9 0.0 8.6e-22 77.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase WW PF00397.26 OWF38011.1 - 2.1e-18 66.1 1.6 5.6e-10 39.1 0.3 2.4 2 0 0 2 2 2 2 WW domain adh_short_C2 PF13561.6 OWF38011.1 - 7.1e-14 51.9 0.0 3e-13 49.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38011.1 - 7.5e-09 35.7 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 KR domain UK PF02512.14 OWF38012.1 - 0.00045 20.7 9.7 1.9e+02 2.6 0.0 8.5 1 1 11 12 12 12 0 Virulence determinant Glyco_hydro_39 PF01229.17 OWF38012.1 - 0.012 14.2 51.4 0.33 9.5 4.0 5.8 1 1 8 9 9 9 0 Glycosyl hydrolases family 39 SH2 PF00017.24 OWF38014.1 - 1.4e-12 47.5 13.5 3 8.0 0.1 10.2 1 1 6 7 7 7 4 SH2 domain Phage_T4_Ndd PF06591.11 OWF38014.1 - 7.4e-06 25.8 6.3 3.8 7.3 0.8 7.1 1 1 6 7 7 7 2 T4-like phage nuclear disruption protein (Ndd) AARP2CN PF08142.12 OWF38014.1 - 8.1e-05 22.6 0.6 61 3.8 0.0 6.8 2 1 3 5 5 5 0 AARP2CN (NUC121) domain DUF4315 PF14193.6 OWF38014.1 - 0.00091 19.2 15.3 38 4.4 0.1 7.9 8 0 0 8 8 8 0 Domain of unknown function (DUF4315) UPRTase PF14681.6 OWF38014.1 - 0.032 13.7 12.3 0.82 9.1 1.1 4.0 1 1 5 6 6 6 0 Uracil phosphoribosyltransferase LexA_DNA_bind PF01726.16 OWF38014.1 - 0.049 13.4 0.3 17 5.3 0.0 4.3 3 2 1 4 4 4 0 LexA DNA binding domain DUF2072 PF09845.9 OWF38014.1 - 0.18 12.1 14.7 4.1 7.7 2.3 3.8 1 1 2 3 3 3 0 Zn-ribbon containing protein DUF5110 PF17137.4 OWF38014.1 - 1.5 9.2 11.7 12 6.3 0.1 4.8 1 1 3 5 5 5 0 Domain of unknown function (DUF5110) Phage_rep_O PF04492.13 OWF38014.1 - 2.6 8.7 4.8 44 4.7 0.2 3.5 1 1 1 2 2 2 0 Bacteriophage replication protein O bZIP_Maf PF03131.17 OWF38015.1 - 3.9e-29 101.0 13.8 6e-29 100.4 13.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF737 PF05300.11 OWF38015.1 - 8.5e-07 29.5 0.6 1.2e-06 29.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) bZIP_2 PF07716.15 OWF38015.1 - 0.0015 18.5 13.5 0.0015 18.5 13.5 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF38015.1 - 0.0057 16.7 15.5 0.0057 16.7 15.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor Tup_N PF08581.10 OWF38015.1 - 0.04 14.2 2.3 0.04 14.2 2.3 1.7 2 0 0 2 2 1 0 Tup N-terminal APG6_N PF17675.1 OWF38015.1 - 0.049 14.1 9.2 0.084 13.4 9.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 OWF38015.1 - 0.071 13.5 3.5 0.15 12.5 3.5 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region GIT_CC PF16559.5 OWF38015.1 - 0.11 12.4 5.9 0.76 9.7 5.8 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 OWF38015.1 - 0.28 10.5 2.3 0.37 10.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 OWF38015.1 - 0.32 8.8 1.0 0.42 8.5 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5320 PF17253.2 OWF38015.1 - 0.46 11.6 1.8 0.95 10.6 1.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) FapA PF03961.13 OWF38015.1 - 0.67 8.5 5.1 0.85 8.2 5.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 OWF38015.1 - 0.89 10.0 5.4 3.2 8.2 5.3 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 OWF38015.1 - 1 9.6 3.7 4.7 7.5 1.3 2.5 3 0 0 3 3 2 0 Haemolysin XhlA MPS2 PF17060.5 OWF38015.1 - 6.7 5.9 10.2 11 5.1 10.2 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 zf-CCCH PF00642.24 OWF38016.1 - 8.6e-13 47.8 30.1 1.2e-05 25.1 3.7 5.4 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OWF38016.1 - 9.4e-07 29.5 25.1 0.02 15.6 1.1 5.7 1 1 4 5 5 5 3 Torus domain zf_CCCH_4 PF18345.1 OWF38016.1 - 4.8e-06 26.4 38.3 0.00024 21.1 5.2 5.9 6 1 0 6 6 6 3 Zinc finger domain zf-CCCH_3 PF15663.5 OWF38016.1 - 8.2e-06 26.0 14.7 0.00043 20.5 3.7 3.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-C3H1 PF10650.9 OWF38016.1 - 0.073 12.8 0.1 0.073 12.8 0.1 3.1 5 0 0 5 5 5 0 Putative zinc-finger domain Glyco_hydro_79C PF16862.5 OWF38016.1 - 0.21 12.5 6.9 0.4 11.6 0.6 3.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain SlyX PF04102.12 OWF38016.1 - 0.9 10.2 3.4 12 6.6 0.3 3.4 3 0 0 3 3 3 0 SlyX zf-CCCH_4 PF18044.1 OWF38016.1 - 6.9 6.6 29.9 0.61 10.0 4.8 4.7 4 0 0 4 4 4 0 CCCH-type zinc finger UQ_con PF00179.26 OWF38017.1 - 1.9e-12 47.0 0.0 1.4e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DUF4581 PF15167.6 OWF38017.1 - 3e-08 33.9 1.8 5.3e-08 33.1 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) RWD PF05773.22 OWF38017.1 - 0.0017 18.7 0.0 0.0048 17.2 0.0 1.9 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 OWF38017.1 - 0.047 13.4 0.0 0.68 9.6 0.0 2.2 2 1 0 2 2 2 0 Prokaryotic E2 family B zf-RanBP PF00641.18 OWF38019.1 - 1.7e-07 30.4 2.1 3.1e-07 29.6 2.1 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others ubiquitin PF00240.23 OWF38019.1 - 1.1e-05 25.1 0.1 3.1e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Vps36-NZF-N PF16988.5 OWF38019.1 - 0.0019 17.5 0.4 0.0043 16.4 0.4 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain W2 PF02020.18 OWF38019.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon YukD PF08817.10 OWF38019.1 - 0.06 14.1 0.0 0.23 12.2 0.0 2.1 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Maf1 PF09174.10 OWF38020.1 - 1.9e-61 207.2 0.0 2.8e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator CAP_GLY PF01302.25 OWF38021.1 - 6.2e-35 119.0 0.6 2.7e-11 43.3 0.1 3.4 3 0 0 3 3 3 3 CAP-Gly domain UCH PF00443.29 OWF38021.1 - 2.2e-07 30.6 0.0 5e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rdx PF10262.9 OWF38021.1 - 0.022 14.9 0.1 7.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Rdx family KASH PF10541.9 OWF38022.1 - 3.5e-05 24.0 4.0 14 6.1 0.0 6.2 3 2 2 7 7 7 2 Nuclear envelope localisation domain CxC4 PF18717.1 OWF38022.1 - 0.00019 21.2 5.8 0.91 9.4 0.1 3.5 1 1 3 4 4 4 3 CxC4 like cysteine cluster associated with KDZ transposases Ribosomal_S13_N PF08069.12 OWF38022.1 - 0.096 12.7 19.8 8.2 6.6 0.1 7.1 1 1 8 10 10 10 0 Ribosomal S13/S15 N-terminal domain bacHORMA_2 PF18173.1 OWF38022.1 - 0.18 11.6 11.7 7.7 6.3 0.3 4.6 1 1 3 5 5 5 0 Bacterial HORMA domain 2 DUF4744 PF15918.5 OWF38022.1 - 9.4 7.2 26.3 23 5.9 0.8 5.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) Y_phosphatase PF00102.27 OWF38023.1 - 2.2e-70 236.9 0.0 2.8e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OWF38023.1 - 0.0048 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF38023.1 - 0.04 13.9 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family OpcA PF07239.11 OWF38024.1 - 0.0016 18.2 0.1 1.8 8.2 0.0 2.1 1 1 0 2 2 2 2 Outer membrane protein OpcA Spc29 PF17082.5 OWF38024.1 - 0.0036 17.2 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF2673 PF10880.8 OWF38025.1 - 3e-08 33.7 91.4 1.8e+02 2.3 0.1 29.5 1 1 34 35 35 35 0 Protein of unknown function (DUF2673) DUF2673 PF10880.8 OWF38026.1 - 0.00058 19.9 5.8 3.3 7.9 0.1 4.5 1 1 4 5 5 5 2 Protein of unknown function (DUF2673) VBS PF08913.10 OWF38026.1 - 0.046 14.2 0.2 15 6.0 0.0 2.8 1 1 3 4 4 4 0 Vinculin Binding Site DUF4105 PF13387.6 OWF38027.1 - 0.065 12.9 0.1 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) SBF2 PF12335.8 OWF38028.1 - 4.3e-09 36.3 4.7 9.8e-09 35.2 4.7 1.6 1 0 0 1 1 1 1 Myotubularin protein DUF3754 PF12576.8 OWF38029.1 - 4.4e-15 55.8 0.2 8.2e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) Sld5 PF05916.11 OWF38030.1 - 5.9e-20 71.8 0.6 7.9e-20 71.4 0.6 1.2 1 0 0 1 1 1 1 GINS complex protein DUF3736 PF12540.8 OWF38031.1 - 2.3e-23 82.8 5.9 2.3e-23 82.8 5.9 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3736) Ank_2 PF12796.7 OWF38032.1 - 8e-19 68.0 1.2 5e-06 27.0 0.1 5.6 3 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38032.1 - 1.5e-13 51.0 0.2 0.00045 20.7 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF38032.1 - 7e-11 42.1 2.3 2.1e-05 24.7 0.1 5.8 4 2 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF38032.1 - 4.1e-10 39.7 0.5 0.0033 17.8 0.1 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OWF38032.1 - 1.8e-09 37.0 0.7 0.0094 16.4 0.0 6.7 7 0 0 7 7 7 2 Ankyrin repeat tRNA_bind PF01588.20 OWF38032.1 - 0.065 13.3 0.3 0.3 11.2 0.0 2.2 3 0 0 3 3 3 0 Putative tRNA binding domain Proteasome PF00227.26 OWF38033.1 - 1e-49 168.6 0.5 1.3e-49 168.3 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_114 PF03537.13 OWF38034.1 - 1.4e-80 270.0 1.4 1.6e-80 269.8 1.4 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF4750 PF15938.5 OWF38035.1 - 2.6e-20 71.8 4.3 2.9e-20 71.7 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) GAPT PF11770.8 OWF38035.1 - 0.043 13.7 0.2 0.044 13.6 0.2 1.2 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) DC_STAMP PF07782.13 OWF38035.1 - 0.045 13.6 0.1 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein DUF3139 PF11337.8 OWF38035.1 - 0.058 14.0 0.1 0.061 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) TMEM208_SND2 PF05620.11 OWF38035.1 - 0.064 13.0 0.0 0.071 12.9 0.0 1.0 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF4148 PF13663.6 OWF38035.1 - 0.21 11.8 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CDT1 PF08839.11 OWF38036.1 - 6.5e-55 186.1 0.5 6.5e-55 186.1 0.5 2.4 2 1 1 3 3 3 1 DNA replication factor CDT1 like CDT1_C PF16679.5 OWF38036.1 - 1.1e-25 89.9 2.0 1.1e-25 89.9 2.0 2.2 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain Ribosomal_S13_N PF08069.12 OWF38037.1 - 0.02 14.9 3.5 0.9 9.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain AP-5_subunit_s1 PF15001.6 OWF38037.1 - 5.6 6.9 8.2 0.45 10.5 2.4 2.1 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 CopC PF04234.12 OWF38037.1 - 6.8 7.8 8.7 0.47 11.5 2.2 2.4 2 1 0 2 2 2 0 CopC domain HEAT PF02985.22 OWF38039.1 - 1.9e-18 65.0 1.0 0.0018 18.3 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 OWF38039.1 - 2.9e-11 43.6 0.1 0.00034 20.9 0.0 5.4 4 2 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 OWF38039.1 - 1.4e-06 28.6 4.7 0.018 15.5 0.2 4.5 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 OWF38039.1 - 0.0045 17.1 3.3 0.33 11.0 0.4 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OWF38039.1 - 0.0055 15.9 4.2 0.4 9.7 0.1 4.0 2 2 2 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 OWF38039.1 - 0.022 14.7 1.2 6.3 6.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) SWI-SNF_Ssr4 PF08549.10 OWF38039.1 - 0.026 13.2 4.6 0.038 12.6 4.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3323 PF11796.8 OWF38039.1 - 0.089 12.7 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) LisH PF08513.11 OWF38039.1 - 0.14 12.2 1.2 0.3 11.1 1.2 1.6 1 0 0 1 1 1 0 LisH UPF0004 PF00919.20 OWF38039.1 - 0.2 11.8 1.0 11 6.1 0.3 3.0 2 1 1 3 3 3 0 Uncharacterized protein family UPF0004 7tm_1 PF00001.21 OWF38040.1 - 0.012 14.9 13.9 0.013 14.8 12.5 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3653 PF12375.8 OWF38040.1 - 0.053 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Phage protein Glyco_transf_10 PF00852.19 OWF38041.1 - 6.5e-48 162.8 1.6 1.1e-47 162.0 1.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF38041.1 - 4.6e-15 56.0 2.7 5.7e-15 55.7 0.2 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal DUF2787 PF10980.8 OWF38041.1 - 0.0024 18.0 0.1 0.0093 16.2 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2787) EF-hand_8 PF13833.6 OWF38042.1 - 4.5e-14 52.0 6.5 4e-07 29.8 0.0 6.1 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_7 PF13499.6 OWF38042.1 - 7.3e-14 52.0 5.6 0.00021 21.7 0.0 5.5 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF38042.1 - 8.6e-12 44.0 5.5 3.5e-05 23.4 0.1 4.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 OWF38042.1 - 1.8e-10 39.6 17.0 2.1e-06 26.9 0.1 5.6 7 1 0 7 7 7 2 EF hand EF-hand_5 PF13202.6 OWF38042.1 - 8.2e-09 34.6 3.5 9.2e-06 24.9 0.1 3.7 3 0 0 3 3 3 2 EF hand DUF4734 PF15881.5 OWF38042.1 - 0.011 15.9 1.2 4.3 7.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) EF-hand_4 PF12763.7 OWF38042.1 - 0.1 12.6 0.1 0.44 10.5 0.0 2.1 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand FGF PF00167.18 OWF38043.1 - 5.8e-17 62.0 0.2 1.2e-16 61.0 0.2 1.4 1 0 0 1 1 1 1 Fibroblast growth factor Nudix_hydro PF18290.1 OWF38044.1 - 1.7e-25 88.8 0.3 3.7e-25 87.7 0.3 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 OWF38044.1 - 2.2e-18 66.6 0.0 3.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MIEAP PF16026.5 OWF38046.1 - 4e-05 23.9 0.8 0.0001 22.6 0.8 1.8 1 1 0 1 1 1 1 Mitochondria-eating protein MIEAP PF16026.5 OWF38047.1 - 7.2e-05 23.1 0.9 0.00015 22.0 0.1 1.8 1 1 1 2 2 2 1 Mitochondria-eating protein Phage_holin_3_6 PF07332.11 OWF38048.1 - 0.0046 17.0 1.3 0.0079 16.2 1.3 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SP_C-Propep PF08999.10 OWF38048.1 - 0.33 10.8 2.6 0.63 9.9 2.6 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ECSCR PF15820.5 OWF38048.1 - 8 6.4 6.6 6.6 6.6 4.0 2.2 2 1 1 3 3 3 0 Endothelial cell-specific chemotaxis regulator 7tm_1 PF00001.21 OWF38050.1 - 5.6e-48 163.6 22.9 7e-48 163.2 22.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF38050.1 - 1.1e-06 28.5 15.9 1.1e-06 28.5 15.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Steroid_dh PF02544.16 OWF38055.1 - 4e-20 72.3 5.3 4e-20 72.3 5.3 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Phage_C PF12025.8 OWF38055.1 - 0.004 17.0 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Phage protein C PhoR PF11808.8 OWF38055.1 - 2.1 8.8 7.1 2.2 8.8 0.1 3.4 4 0 0 4 4 4 0 Phosphate regulon sensor protein PhoR PDZ PF00595.24 OWF38056.1 - 0.039 14.3 0.2 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 PDZ domain DUF4528 PF15031.6 OWF38056.1 - 0.084 12.9 1.4 4.6 7.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4528) R-HINP1I PF11463.8 OWF38057.1 - 0.039 13.4 0.2 0.33 10.4 0.2 1.9 1 1 1 2 2 2 0 R.HinP1I restriction endonuclease RED_N PF07808.13 OWF38058.1 - 1.3e-98 329.2 9.5 1.3e-98 329.2 9.5 3.6 2 1 2 4 4 4 1 RED-like protein N-terminal region RED_C PF07807.11 OWF38058.1 - 2.6e-54 182.5 6.4 2.6e-54 182.5 6.4 4.1 5 0 0 5 5 5 1 RED-like protein C-terminal region Lsm_interact PF05391.11 OWF38058.1 - 0.0055 16.2 1.7 0.017 14.6 1.7 1.9 1 0 0 1 1 1 1 Lsm interaction motif DUF2924 PF11149.8 OWF38058.1 - 0.091 13.2 4.0 6.1 7.2 0.5 3.6 2 2 0 3 3 3 0 Protein of unknown function (DUF2924) DUF2011 PF09428.10 OWF38058.1 - 0.41 10.9 6.2 0.94 9.8 0.9 2.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) LRR_8 PF13855.6 OWF38059.1 - 2.8e-18 65.4 12.3 2e-10 40.3 1.0 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF38059.1 - 1.3e-10 41.3 11.3 5.5e-05 23.5 2.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF38059.1 - 0.00017 21.3 12.5 4.2 7.7 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 OWF38059.1 - 0.0002 21.5 12.0 3.8 8.4 1.1 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat AFT PF08731.11 OWF38059.1 - 1.1 9.7 6.2 1.7 9.0 6.2 1.3 1 0 0 1 1 1 0 Transcription factor AFT DDHD PF02862.17 OWF38059.1 - 1.3 9.1 4.6 1.7 8.8 4.6 1.2 1 0 0 1 1 1 0 DDHD domain CobT PF06213.12 OWF38059.1 - 1.9 7.8 18.6 2.6 7.4 18.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 OWF38059.1 - 8.7 5.7 11.9 11 5.4 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop25 PF09805.9 OWF38059.1 - 8.8 6.8 24.8 15 6.1 24.8 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FAM163 PF15069.6 OWF38060.1 - 0.12 12.9 0.8 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 FAM163 family Lig_chan PF00060.26 OWF38062.1 - 2.2e-45 154.2 0.8 3.4e-45 153.5 0.8 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 OWF38062.1 - 6.8e-39 134.0 0.1 9.9e-39 133.4 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 OWF38062.1 - 2.7e-37 127.5 0.1 6.1e-37 126.3 0.1 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF38062.1 - 2.1e-16 60.1 0.0 4.9e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF5589 PF17672.1 OWF38062.1 - 0.17 11.8 1.5 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5589) LapA_dom PF06305.11 OWF38062.1 - 1.2 9.1 4.1 0.76 9.6 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Lig_chan PF00060.26 OWF38063.1 - 3.1e-58 195.8 0.4 4.8e-58 195.2 0.4 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF38063.1 - 2.2e-38 131.0 0.0 5.8e-38 129.6 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 OWF38063.1 - 3.7e-32 111.8 0.3 7.1e-32 110.9 0.0 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 OWF38063.1 - 4.3e-22 78.7 0.0 9.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 OWF38063.1 - 0.016 14.9 0.0 8.6 5.9 0.0 2.6 3 0 0 3 3 3 0 Periplasmic binding protein Lig_chan PF00060.26 OWF38064.1 - 1.1e-53 181.0 0.2 1.9e-53 180.3 0.2 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF38064.1 - 8.4e-34 116.2 0.0 1.7e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 OWF38064.1 - 1.4e-24 86.9 0.0 2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 OWF38064.1 - 3.1e-21 75.9 0.0 8.5e-21 74.4 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Cation_ATPase_C PF00689.21 OWF38064.1 - 0.043 13.5 4.7 0.039 13.7 3.0 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus LapA_dom PF06305.11 OWF38064.1 - 2 8.3 3.8 2.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Lig_chan PF00060.26 OWF38065.1 - 2.3e-46 157.3 0.5 3.8e-46 156.6 0.5 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF38065.1 - 6.8e-40 135.8 0.0 1.6e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 OWF38065.1 - 5e-34 118.0 0.0 7.2e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 OWF38065.1 - 1.6e-26 93.1 0.0 3.1e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 RXT2_N PF08595.11 OWF38065.1 - 0.015 15.3 0.1 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal TED_complement PF07678.14 OWF38066.1 - 1.9e-90 303.1 0.0 2.7e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 OWF38066.1 - 2.5e-28 99.2 1.5 2.4e-26 92.8 0.1 4.0 4 0 0 4 4 4 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 OWF38066.1 - 2e-21 75.6 0.3 6.7e-21 74.0 0.3 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG2 PF01835.19 OWF38066.1 - 4.1e-15 56.0 0.1 3.1e-13 50.0 0.0 3.8 4 0 0 4 4 4 1 MG2 domain A2M_recep PF07677.14 OWF38066.1 - 3.4e-14 53.3 0.9 1.5e-13 51.3 0.1 2.4 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG3 PF17791.1 OWF38066.1 - 9.9e-14 51.4 0.0 2.9e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 OWF38066.1 - 0.0054 16.8 4.2 0.65 10.2 0.1 3.9 4 0 0 4 4 4 1 Macroglobulin domain MG4 MG1 PF17790.1 OWF38066.1 - 0.022 15.2 0.9 0.12 12.8 0.0 2.8 3 0 0 3 3 3 0 Macroglobulin domain MG1 SQHop_cyclase_C PF13243.6 OWF38066.1 - 0.18 10.9 0.0 0.64 9.1 0.0 1.8 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 OWF38066.1 - 2.8 7.8 4.7 25 4.7 0.0 3.2 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat FRG1 PF06229.12 OWF38067.1 - 3.7e-66 222.5 0.0 5.9e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 OWF38067.1 - 5.6e-12 45.9 0.0 4e-11 43.1 0.0 2.0 1 1 1 2 2 2 1 Fascin domain DUF1754 PF08555.10 OWF38067.1 - 4.2e-06 27.5 2.7 4.2e-06 27.5 2.7 2.0 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF569 PF04601.13 OWF38067.1 - 0.026 14.2 0.2 0.13 12.0 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF569) Cadherin PF00028.17 OWF38069.1 - 0 1385.2 93.1 1.6e-22 79.8 0.1 27.4 27 0 0 27 27 27 27 Cadherin domain Cadherin_2 PF08266.12 OWF38069.1 - 1.4e-24 85.7 0.0 0.38 10.6 0.0 18.1 21 0 0 21 21 21 3 Cadherin-like Cadherin_3 PF16184.5 OWF38069.1 - 1e-16 60.9 72.3 0.058 13.4 0.0 21.2 20 1 1 21 21 21 5 Cadherin-like RET_CLD1 PF17756.1 OWF38069.1 - 1.3e-13 51.3 1.4 0.033 14.5 0.0 10.5 12 1 1 13 13 11 2 RET Cadherin like domain 1 Cadherin_pro PF08758.11 OWF38069.1 - 1.7e-11 44.2 10.5 0.58 10.4 0.2 9.8 9 0 0 9 9 9 3 Cadherin prodomain like He_PIG PF05345.12 OWF38069.1 - 0.00043 20.4 21.8 4.1 7.7 0.1 11.1 10 0 0 10 10 10 1 Putative Ig domain TMEM154 PF15102.6 OWF38069.1 - 0.0075 16.2 0.4 0.0075 16.2 0.4 2.3 2 0 0 2 2 1 1 TMEM154 protein family Cadherin_C PF01049.17 OWF38069.1 - 0.011 16.1 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic region ResB PF05140.14 OWF38069.1 - 0.027 13.2 0.3 0.066 11.9 0.3 1.6 1 0 0 1 1 1 0 ResB-like family EphA2_TM PF14575.6 OWF38069.1 - 0.041 14.8 0.1 0.1 13.5 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OWF38069.1 - 0.048 13.6 0.6 0.11 12.4 0.6 1.5 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 OWF38069.1 - 0.089 11.6 0.5 6.6 5.4 0.0 2.7 3 0 0 3 3 3 0 Amnionless SIT PF15330.6 OWF38069.1 - 0.099 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Y_Y_Y PF07495.13 OWF38069.1 - 0.16 11.9 8.2 22 5.1 0.0 7.1 8 0 0 8 8 7 0 Y_Y_Y domain Pilin_N PF07790.11 OWF38069.1 - 0.81 10.7 4.4 14 6.7 0.5 4.5 3 0 0 3 3 2 0 Archaeal Type IV pilin, N-terminal TMEM52 PF14979.6 OWF38069.1 - 0.81 9.6 4.0 6.9 6.6 0.4 4.0 3 0 0 3 3 3 0 Transmembrane 52 ASFV_J13L PF05568.11 OWF38069.1 - 3.5 7.4 8.4 0.17 11.6 1.0 2.5 2 0 0 2 2 2 0 African swine fever virus J13L protein Prefoldin_2 PF01920.20 OWF38070.1 - 0.00011 22.1 0.4 0.0014 18.5 0.2 2.5 2 1 0 2 2 2 1 Prefoldin subunit Bac_rhamnosid PF05592.11 OWF38070.1 - 0.0093 15.9 0.1 6 6.9 0.0 3.4 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain MMR_HSR1_Xtn PF16897.5 OWF38070.1 - 0.4 10.7 5.3 3.8 7.6 0.5 3.1 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain Acetyltransf_1 PF00583.25 OWF38074.1 - 5.7e-14 52.4 0.0 7.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF38074.1 - 2.7e-08 33.8 0.0 1.3e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OWF38074.1 - 3.8e-07 30.2 0.0 2.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF38074.1 - 2.7e-06 27.7 0.0 3.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OWF38074.1 - 0.0043 17.0 0.1 0.0069 16.3 0.1 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase PanZ PF12568.8 OWF38074.1 - 0.026 14.3 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Choline_kinase PF01633.20 OWF38074.1 - 0.057 13.0 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase FR47 PF08445.10 OWF38074.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein GST_C PF00043.25 OWF38075.1 - 2.6e-07 30.8 0.0 4.5e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF38075.1 - 3.5e-07 30.3 0.0 8.6e-07 29.1 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF38075.1 - 4.5e-05 23.4 0.0 8.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OWF38075.1 - 0.045 13.5 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF38075.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Methyltransf_22 PF13383.6 OWF38076.1 - 1.9e-22 80.1 1.2 2.3e-22 79.8 1.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF38076.1 - 0.0004 20.5 0.3 0.0074 16.3 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase FkbM domain YdiH PF15930.5 OWF38076.1 - 0.12 12.5 0.1 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Pkinase PF00069.25 OWF38077.1 - 3.4e-69 233.1 0.0 4.8e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38077.1 - 4.6e-35 121.2 0.0 9.7e-35 120.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF38077.1 - 0.00048 19.5 0.0 0.003 16.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OWF38077.1 - 0.0066 15.4 0.2 0.011 14.6 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Ig_3 PF13927.6 OWF38078.1 - 4.2e-40 136.2 11.8 5.2e-14 52.6 0.1 5.9 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 OWF38078.1 - 2e-27 95.0 1.9 2.6e-10 40.2 0.0 5.8 6 0 0 6 6 6 5 Immunoglobulin I-set domain ig PF00047.25 OWF38078.1 - 7.7e-27 93.3 8.9 3.4e-08 33.5 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 OWF38078.1 - 3.2e-24 85.0 5.7 1.3e-06 28.7 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain C2-set_2 PF08205.12 OWF38078.1 - 5.3e-23 80.9 2.3 9.9e-09 35.2 0.0 4.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF38078.1 - 1e-17 64.2 4.2 1.1e-07 32.0 0.0 6.4 5 2 0 5 5 5 3 Immunoglobulin V-set domain C1-set PF07654.15 OWF38078.1 - 6.2e-09 36.1 0.4 0.034 14.5 0.0 5.2 4 1 0 4 4 4 2 Immunoglobulin C1-set domain fn3 PF00041.21 OWF38078.1 - 3.1e-05 24.2 0.0 0.00011 22.5 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain Izumo-Ig PF16706.5 OWF38078.1 - 0.037 14.1 0.1 13 5.9 0.1 3.0 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 OWF38078.1 - 0.15 12.3 0.0 8.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 EphA2_TM PF14575.6 OWF38078.1 - 0.16 12.9 0.0 0.39 11.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Aa_trans PF01490.18 OWF38079.1 - 1.1e-83 281.2 33.2 1.4e-83 280.9 33.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RPA_C PF08784.11 OWF38080.1 - 4.2e-18 65.9 2.2 4.2e-18 65.9 2.2 2.1 2 1 1 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OWF38080.1 - 3.3e-06 27.0 0.0 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain STN1_2 PF09170.10 OWF38080.1 - 0.00044 20.5 0.4 0.17 12.1 0.0 2.4 3 0 0 3 3 3 2 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 RMI2 PF16100.5 OWF38080.1 - 0.0025 17.6 0.1 0.0059 16.4 0.0 1.6 2 0 0 2 2 2 1 RecQ-mediated genome instability protein 2 GAPT PF11770.8 OWF38080.1 - 0.018 14.9 0.3 0.073 12.9 0.0 1.8 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) IFS PF16718.5 OWF38081.1 - 0.64 10.1 11.2 99 3.0 0.1 7.5 6 3 5 11 11 11 0 Immunity factor for SPN Glyco_hydro_31 PF01055.26 OWF38082.1 - 0 1429.2 21.1 2.8e-149 498.0 1.1 3.2 3 0 0 3 3 3 3 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OWF38082.1 - 5.2e-74 245.9 3.2 4.6e-28 97.7 0.0 3.6 3 0 0 3 3 3 3 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OWF38082.1 - 1.8e-20 73.0 10.8 2.3e-07 31.1 0.3 3.8 3 0 0 3 3 3 3 Galactose mutarotase-like DUF5110 PF17137.4 OWF38082.1 - 1.8e-14 53.7 1.9 0.00015 22.0 0.0 4.3 3 0 0 3 3 3 3 Domain of unknown function (DUF5110) Trefoil PF00088.18 OWF38082.1 - 5.4e-13 48.6 18.9 8.4e-06 25.6 1.0 3.9 4 0 0 4 4 4 3 Trefoil (P-type) domain EAV_GP5 PF15981.5 OWF38082.1 - 0.0016 18.8 0.1 7.8 7.0 0.0 3.7 3 0 0 3 3 3 2 Envelope glycoprotein GP 5 of equine arteritis virus Pik1 PF11522.8 OWF38082.1 - 0.036 14.0 0.7 10 6.2 0.0 3.7 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Rad17 PF03215.15 OWF38083.1 - 5.7e-45 153.5 0.0 1e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OWF38083.1 - 0.00063 20.2 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OWF38083.1 - 0.00084 19.9 0.2 0.0036 17.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain Herpes_Helicase PF02689.14 OWF38083.1 - 0.0057 14.7 0.0 0.0088 14.0 0.0 1.1 1 0 0 1 1 1 1 Helicase Zeta_toxin PF06414.12 OWF38083.1 - 0.0068 15.7 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_assoc_2 PF16193.5 OWF38083.1 - 0.022 15.1 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA C-terminal domain AAA PF00004.29 OWF38083.1 - 0.049 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF38083.1 - 0.051 13.8 0.3 0.18 12.0 0.1 2.1 2 1 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 OWF38083.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 OWF38083.1 - 0.079 13.0 0.1 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 OWF38083.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 OWF38083.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 OWF38083.1 - 0.13 12.1 0.2 0.81 9.5 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 OWF38083.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3429 PF11911.8 OWF38084.1 - 4.3e-36 124.4 12.3 5.8e-36 123.9 12.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Thiolase_C PF02803.18 OWF38085.1 - 1.8e-12 47.0 0.2 3.5e-10 39.6 0.0 2.7 2 1 1 3 3 3 2 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 OWF38085.1 - 0.015 15.4 0.2 0.63 10.1 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 OWF38086.1 - 3.7e-08 33.1 0.0 4e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain DSBA PF01323.20 OWF38086.1 - 0.031 14.0 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain adh_short PF00106.25 OWF38087.1 - 1e-34 119.7 0.1 1.6e-34 119.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38087.1 - 9.1e-30 103.9 0.1 1.4e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 OWF38087.1 - 1.1e-24 86.8 0.1 2.7e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 OWF38087.1 - 0.00013 21.9 0.2 0.00024 21.1 0.2 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 OWF38087.1 - 0.00037 20.7 0.0 0.00073 19.8 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal THF_DHG_CYH_C PF02882.19 OWF38087.1 - 0.11 11.8 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GWT1 PF06423.12 OWF38088.1 - 7.3e-33 113.8 8.7 7.3e-33 113.8 8.7 3.2 3 0 0 3 3 3 1 GWT1 DUF3852 PF12963.7 OWF38088.1 - 3.3 8.1 7.9 1.1 9.7 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) adh_short PF00106.25 OWF38089.1 - 6.9e-37 126.8 0.3 8.9e-37 126.4 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38089.1 - 2.3e-33 115.7 0.7 3.1e-33 115.3 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38089.1 - 4.2e-06 26.8 0.1 6.2e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OWF38089.1 - 0.039 13.3 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 OWF38089.1 - 0.077 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eaf7 PF07904.13 OWF38090.1 - 2.9e-13 50.1 4.0 1.1e-12 48.2 3.9 2.3 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 CDC45 PF02724.14 OWF38090.1 - 0.077 11.3 1.8 0.07 11.4 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.29 OWF38091.1 - 8.7e-47 159.1 0.0 1.4e-45 155.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.29 OWF38091.1 - 7e-31 105.9 16.1 7.5e-16 57.7 0.9 3.2 3 0 0 3 3 3 2 KH domain Helicase_C PF00271.31 OWF38091.1 - 2.7e-30 105.0 0.1 2.4e-28 98.7 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 OWF38091.1 - 2.6e-14 52.5 14.2 3.3e-07 30.1 3.4 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_2 PF07650.17 OWF38091.1 - 2.1e-09 37.1 2.6 0.00022 21.0 0.2 2.7 2 0 0 2 2 2 2 KH domain ResIII PF04851.15 OWF38091.1 - 7.9e-06 26.0 0.5 4.5e-05 23.5 0.0 2.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit zf-CCHC_3 PF13917.6 OWF38091.1 - 1.7e-05 24.6 7.1 0.011 15.7 0.4 3.1 3 0 0 3 3 3 2 Zinc knuckle KH_4 PF13083.6 OWF38091.1 - 2.5e-05 24.1 3.2 0.14 12.1 0.1 3.2 2 1 0 2 2 2 2 KH domain MOEP19 PF16005.5 OWF38091.1 - 5.1e-05 23.2 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 2 KH-like RNA-binding domain CMS1 PF14617.6 OWF38091.1 - 5.5e-05 22.6 0.0 0.00015 21.2 0.0 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit KH_5 PF13184.6 OWF38091.1 - 0.00055 20.0 1.6 0.077 13.1 0.3 2.6 2 0 0 2 2 2 1 NusA-like KH domain GRP PF07172.11 OWF38091.1 - 0.019 15.6 13.9 0.019 15.6 13.9 4.8 4 1 0 4 4 2 0 Glycine rich protein family Z1 PF10593.9 OWF38091.1 - 0.11 12.0 0.1 0.94 8.9 0.1 2.2 2 0 0 2 2 2 0 Z1 domain zf-CCHC_5 PF14787.6 OWF38091.1 - 0.14 11.9 7.1 2 8.2 0.7 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 OWF38091.1 - 1.1 9.1 6.2 4.4 7.1 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle Acetyltransf_13 PF13880.6 OWF38092.1 - 4.1e-29 100.4 0.0 8.9e-29 99.3 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OWF38092.1 - 1.6e-16 59.8 0.4 3.2e-16 58.9 0.4 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 OWF38092.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF38092.1 - 0.085 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Rhodanese PF00581.20 OWF38093.1 - 5e-09 36.6 0.0 9.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 OWF38094.1 - 1.3e-11 44.9 0.0 3.8e-11 43.4 0.0 1.7 1 1 1 2 2 2 1 Rhodanese-like domain Rhodanese PF00581.20 OWF38095.1 - 3.8e-12 46.7 0.0 6.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain T4_gp9_10 PF07880.11 OWF38096.1 - 2.2 7.8 4.4 76 2.7 0.0 4.2 1 1 4 5 5 5 0 Bacteriophage T4 gp9/10-like protein DUF2247 PF10004.9 OWF38096.1 - 7.1 6.4 28.1 63 3.3 0.4 7.5 1 1 13 14 14 14 0 Uncharacterized protein conserved in bacteria (DUF2247) Rhodanese PF00581.20 OWF38097.1 - 1.6e-11 44.7 0.1 3.2e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Rhodanese-like domain SH3_2 PF07653.17 OWF38098.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Profilin PF00235.19 OWF38099.1 - 3.7e-10 40.2 0.0 4.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Profilin SSDP PF04503.13 OWF38100.1 - 3.5e-45 155.5 94.7 1e-22 81.7 58.0 3.1 1 1 2 3 3 3 3 Single-stranded DNA binding protein, SSDP Autophagy_act_C PF03987.15 OWF38101.1 - 5.8e-19 68.4 1.5 1.2e-18 67.4 0.9 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Arf PF00025.21 OWF38102.1 - 7.4e-66 220.9 0.1 1.9e-65 219.6 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF38102.1 - 2.3e-15 56.9 0.1 4.9e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF38102.1 - 4.9e-15 55.5 0.3 1.1e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 Ras family G-alpha PF00503.20 OWF38102.1 - 8.8e-10 38.3 3.3 3.5e-09 36.3 3.3 2.1 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 OWF38102.1 - 1.1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF38102.1 - 1.7e-07 30.9 2.1 6.2e-07 29.0 0.0 2.6 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region zf-B_box PF00643.24 OWF38102.1 - 9.8e-07 28.8 6.8 9.8e-07 28.8 6.8 4.7 5 0 0 5 5 4 2 B-box zinc finger zf-RING_5 PF14634.6 OWF38102.1 - 3.2e-05 23.8 3.6 3.2e-05 23.8 3.6 3.9 3 1 0 3 3 2 1 zinc-RING finger domain MMR_HSR1 PF01926.23 OWF38102.1 - 0.0001 22.4 0.2 0.00033 20.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-RING_UBOX PF13445.6 OWF38102.1 - 0.00017 21.5 6.4 0.00017 21.5 6.4 3.0 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF38102.1 - 0.00069 19.9 4.1 0.00069 19.9 4.1 4.7 4 1 0 4 4 4 1 Ring finger domain NACHT PF05729.12 OWF38102.1 - 0.011 15.7 1.6 2.6 7.9 0.0 3.1 3 0 0 3 3 3 0 NACHT domain Prok-RING_4 PF14447.6 OWF38102.1 - 0.016 15.0 4.1 0.016 15.0 4.1 3.2 4 0 0 4 4 2 0 Prokaryotic RING finger family 4 cobW PF02492.19 OWF38102.1 - 0.016 14.8 0.0 9.1 5.8 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain zf-C3HC4 PF00097.25 OWF38102.1 - 0.017 15.0 3.2 0.017 15.0 3.2 3.4 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF1387 PF07139.11 OWF38102.1 - 0.026 14.3 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) FYVE PF01363.21 OWF38102.1 - 0.039 14.1 0.2 0.039 14.1 0.2 3.7 2 1 0 2 2 1 0 FYVE zinc finger AAA_14 PF13173.6 OWF38102.1 - 0.056 13.5 0.6 0.99 9.4 0.1 2.7 2 1 0 2 2 1 0 AAA domain Ribosomal_L40e PF01020.17 OWF38102.1 - 0.065 13.1 1.7 1.9 8.4 0.6 3.1 2 0 0 2 2 2 0 Ribosomal L40e family FemAB PF02388.16 OWF38102.1 - 0.21 10.4 0.7 0.36 9.6 0.7 1.3 1 0 0 1 1 1 0 FemAB family ATG16 PF08614.11 OWF38102.1 - 2.9 8.1 11.8 0.24 11.6 6.8 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 OWF38102.1 - 4.5 7.8 5.3 1.9 9.0 0.2 2.7 2 2 0 2 2 2 0 ABC transporter SBF PF01758.16 OWF38103.1 - 6.2e-16 58.6 13.3 8.8e-16 58.1 12.2 1.8 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF974 PF06159.13 OWF38105.1 - 1.8e-82 276.9 0.1 2.3e-82 276.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 OWF38105.1 - 0.0026 17.3 0.0 1.3 8.3 0.0 3.0 3 0 0 3 3 3 2 TRAPP trafficking subunit Trs65 Reeler PF02014.16 OWF38106.1 - 2.6e-27 96.1 0.1 3.6e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 Reeler domain Y_phosphatase PF00102.27 OWF38107.1 - 5e-109 363.4 0.2 1.3e-72 244.1 0.5 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF38107.1 - 1.2e-05 25.1 0.0 3.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain F5_F8_type_C PF00754.25 OWF38107.1 - 0.0039 17.3 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Y_phosphatase3 PF13350.6 OWF38107.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OWF38107.1 - 0.022 14.9 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate EphA2_TM PF14575.6 OWF38107.1 - 0.08 13.8 0.0 0.25 12.3 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myc_target_1 PF15179.6 OWF38107.1 - 0.17 11.8 0.3 2.1 8.2 0.4 2.2 2 0 0 2 2 2 0 Myc target protein 1 Lipocalin_2 PF08212.12 OWF38108.1 - 2.7e-12 46.8 0.0 3.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF38108.1 - 2.5e-11 44.0 0.0 3.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF38108.1 - 0.0027 17.6 0.1 0.0072 16.2 0.0 1.7 2 0 0 2 2 2 1 Triabin Coat_F PF07875.12 OWF38109.1 - 4.8e-13 49.1 17.0 0.026 14.7 0.0 9.9 10 0 0 10 10 10 5 Coat F domain HALZ PF02183.18 OWF38109.1 - 0.0012 19.0 5.7 0.0059 16.8 0.6 33.4 39 0 0 39 39 39 13 Homeobox associated leucine zipper 7tm_2 PF00002.24 OWF38110.1 - 2.3e-65 220.3 15.7 3.7e-65 219.6 15.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 OWF38110.1 - 3.5e-29 101.8 4.9 5.3e-29 101.2 4.9 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 OWF38110.1 - 1.7e-18 66.8 2.6 1.7e-18 66.8 2.6 2.4 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.21 OWF38110.1 - 1.1e-16 61.1 5.7 3.6e-16 59.4 5.7 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 OWF38110.1 - 0.011 16.0 3.3 0.036 14.4 3.3 1.9 1 0 0 1 1 1 0 Hormone receptor domain CrgA PF06781.12 OWF38110.1 - 0.016 15.2 0.1 0.016 15.2 0.1 3.2 3 0 0 3 3 3 0 Cell division protein CrgA DUF4834 PF16118.5 OWF38110.1 - 2.6 9.1 4.2 20 6.2 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) SWIRM PF04433.17 OWF38111.1 - 2.3e-21 75.9 0.0 5.5e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 OWF38111.1 - 8.1e-11 42.0 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain JAB PF01398.21 OWF38111.1 - 1.9e-09 37.5 0.1 5.5e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OWF38111.1 - 9.6e-07 28.6 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_7 PF15963.5 OWF38111.1 - 3e-06 27.0 0.1 7.3e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OWF38111.1 - 0.00028 21.1 0.1 0.00068 19.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0172 PF03665.13 OWF38111.1 - 0.0065 16.5 1.0 0.013 15.5 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) BP28CT PF08146.12 OWF38112.1 - 2.1e-40 138.2 0.2 2.1e-40 138.2 0.2 5.6 6 0 0 6 6 6 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OWF38112.1 - 1.1e-20 74.1 10.1 1.1e-20 74.1 10.1 6.8 6 1 1 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 OWF38112.1 - 3.7e-05 24.0 3.6 0.24 11.8 0.0 6.3 7 0 0 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 OWF38112.1 - 0.0049 17.4 1.5 13 6.4 0.0 5.6 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OWF38112.1 - 0.045 14.3 7.0 0.99 10.0 0.0 6.3 7 0 0 7 7 7 0 HEAT-like repeat DUF3201 PF11447.8 OWF38112.1 - 0.11 12.0 0.0 0.7 9.4 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) DEP PF00610.21 OWF38113.1 - 7.5e-39 131.6 2.8 6.6e-19 67.7 0.5 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 OWF38113.1 - 1.6e-08 34.2 0.1 2.6e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF38113.1 - 0.0008 19.7 0.1 0.0018 18.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF38113.1 - 0.002 18.5 0.1 0.0033 17.7 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Y_phosphatase PF00102.27 OWF38114.1 - 5.7e-108 359.9 3.4 6.1e-73 245.3 0.2 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF38114.1 - 1.1e-07 31.7 0.1 0.00032 20.5 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF38114.1 - 0.00018 21.7 0.0 0.0012 19.0 0.0 2.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF38114.1 - 0.00036 20.6 0.4 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family EphA2_TM PF14575.6 OWF38114.1 - 0.0058 17.5 0.0 0.02 15.8 0.0 1.9 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3700 PF12481.8 OWF38114.1 - 0.085 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein TMEM154 PF15102.6 OWF38114.1 - 0.098 12.6 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family RTP1_C1 PF10363.9 OWF38114.1 - 0.14 12.4 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 PTP_tm PF18861.1 OWF38114.1 - 0.14 12.2 0.4 0.34 10.9 0.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TnpW PF14202.6 OWF38115.1 - 0.017 15.0 0.1 0.055 13.3 0.1 1.9 1 0 0 1 1 1 0 Transposon-encoded protein TnpW IgGFc_binding PF17517.2 OWF38116.1 - 9.9e-28 97.2 6.3 9.9e-28 97.2 6.3 2.2 1 1 1 2 2 2 1 IgGFc binding protein Cu-binding_MopE PF11617.8 OWF38116.1 - 0.035 14.3 1.2 0.1 12.8 1.2 1.8 1 0 0 1 1 1 0 Putative metal-binding motif Dcc1 PF09724.9 OWF38117.1 - 3.8e-97 325.6 2.1 4.5e-97 325.3 2.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 C1q PF00386.21 OWF38118.1 - 2.6e-21 76.1 0.1 3.5e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 C1q domain Lebercilin PF15619.6 OWF38118.1 - 0.029 14.0 0.5 0.036 13.7 0.5 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease RmuC PF02646.16 OWF38118.1 - 0.034 13.3 0.4 0.043 12.9 0.4 1.1 1 0 0 1 1 1 0 RmuC family CtIP_N PF10482.9 OWF38118.1 - 0.036 14.1 0.3 0.047 13.7 0.3 1.2 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain HALZ PF02183.18 OWF38118.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Phage_lysis PF03245.13 OWF38118.1 - 0.098 12.8 1.4 0.16 12.1 1.4 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein TolA_bind_tri PF16331.5 OWF38118.1 - 0.16 12.1 2.4 0.84 9.8 2.4 2.0 1 1 0 1 1 1 0 TolA binding protein trimerisation bZIP_2 PF07716.15 OWF38118.1 - 0.16 12.1 0.9 0.83 9.8 0.3 2.0 1 1 1 2 2 2 0 Basic region leucine zipper TRAF_BIRC3_bd PF16673.5 OWF38118.1 - 0.46 10.3 4.8 0.75 9.6 0.2 2.6 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain C1q PF00386.21 OWF38119.1 - 1.1e-19 70.9 0.0 2.2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 C1q domain Spc7 PF08317.11 OWF38119.1 - 0.027 13.3 1.1 0.037 12.9 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 OWF38119.1 - 0.09 13.1 2.5 7.5 7.0 0.3 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSBP1 PF06825.12 OWF38119.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.2 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Insulin PF00049.18 OWF38120.1 - 1.8e-07 32.0 1.0 3.8e-07 31.0 1.0 1.5 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family SWIM PF04434.17 OWF38121.1 - 0.0019 17.8 0.2 0.0044 16.7 0.2 1.7 1 0 0 1 1 1 1 SWIM zinc finger ADIP PF11559.8 OWF38122.1 - 1.5e-25 90.1 14.4 1.5e-25 90.1 14.4 3.1 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding DUF2334 PF10096.9 OWF38122.1 - 0.025 14.3 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Exonuc_VII_L PF02601.15 OWF38122.1 - 0.025 14.2 21.8 0.028 14.0 5.6 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit ERM PF00769.19 OWF38122.1 - 0.05 13.4 38.7 0.043 13.6 19.3 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF963 PF06131.11 OWF38124.1 - 3.2e-09 36.1 103.9 0.02 14.3 2.2 16.9 13 4 2 17 17 17 12 Schizosaccharomyces pombe repeat of unknown function (DUF963) zf-B_box PF00643.24 OWF38124.1 - 5.1e-08 32.9 19.0 9e-07 29.0 0.4 2.5 1 1 1 2 2 2 2 B-box zinc finger UPF0542 PF15086.6 OWF38125.1 - 1.6e-26 92.0 5.7 1.8e-26 91.8 5.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 OAD_gamma PF04277.13 OWF38125.1 - 0.0069 17.0 2.4 0.0095 16.5 2.4 1.2 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Ctr PF04145.15 OWF38125.1 - 0.011 16.4 0.4 0.011 16.3 0.4 1.0 1 0 0 1 1 1 0 Ctr copper transporter family TMEM100 PF16311.5 OWF38125.1 - 0.035 13.7 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 DUF3767 PF12597.8 OWF38125.1 - 0.05 13.4 0.5 0.063 13.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) TMEMspv1-c74-12 PF11044.8 OWF38125.1 - 0.056 13.4 2.4 0.12 12.4 2.4 1.5 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Connexin PF00029.19 OWF38125.1 - 0.083 12.6 0.1 0.089 12.5 0.1 1.0 1 0 0 1 1 1 0 Connexin BatD PF13584.6 OWF38125.1 - 0.095 11.5 1.3 0.095 11.5 1.3 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF2206 PF09971.9 OWF38125.1 - 0.16 10.7 0.1 0.18 10.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) NDUFA12 PF05071.16 OWF38126.1 - 8.1e-11 42.6 1.4 1.5e-10 41.7 0.8 1.7 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 RNase_J_C PF17770.1 OWF38127.1 - 0.13 13.3 0.1 0.8 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain IMP2_N PF18590.1 OWF38127.1 - 0.26 11.9 1.4 1.4 9.6 0.1 2.1 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) N-terminal domain TGF_beta PF00019.20 OWF38128.1 - 4e-21 75.9 1.0 8.1e-21 75.0 1.0 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 OWF38128.1 - 0.017 14.8 1.1 0.049 13.4 0.9 2.0 1 1 0 1 1 1 0 TGF-beta propeptide F5_F8_type_C PF00754.25 OWF38129.1 - 6.2e-06 26.3 0.0 8.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain LURAP PF14854.6 OWF38130.1 - 0.0017 18.3 3.1 0.0066 16.4 3.1 2.0 1 1 0 1 1 1 1 Leucine rich adaptor protein LURAP PF14854.6 OWF38131.1 - 0.00018 21.4 3.5 0.00018 21.4 3.5 2.0 2 0 0 2 2 2 1 Leucine rich adaptor protein FAM167 PF11652.8 OWF38131.1 - 0.012 16.1 1.3 0.027 14.9 1.3 1.7 1 0 0 1 1 1 0 FAM167 LURAP PF14854.6 OWF38132.1 - 0.00048 20.1 8.2 0.0024 17.8 8.0 2.1 1 1 0 1 1 1 1 Leucine rich adaptor protein FAM167 PF11652.8 OWF38132.1 - 0.0083 16.6 3.7 0.014 15.8 1.5 2.3 1 1 1 2 2 2 1 FAM167 LURAP PF14854.6 OWF38133.1 - 3.2e-09 36.8 0.8 3.2e-09 36.8 0.8 1.9 2 0 0 2 2 2 1 Leucine rich adaptor protein LURAP PF14854.6 OWF38135.1 - 1.4e-07 31.5 1.3 3.1e-07 30.4 1.4 1.6 1 1 1 2 2 2 1 Leucine rich adaptor protein LURAP PF14854.6 OWF38136.1 - 4.8e-07 29.7 2.1 4.8e-07 29.7 2.1 2.2 2 1 0 2 2 2 1 Leucine rich adaptor protein RhoGAP PF00620.27 OWF38137.1 - 4.5e-41 140.2 0.1 8.7e-41 139.3 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PDZ PF00595.24 OWF38137.1 - 3.3e-12 46.6 0.5 7.6e-12 45.4 0.5 1.6 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 OWF38137.1 - 8.4e-07 29.2 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 OWF38137.1 - 0.00079 19.2 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF38137.1 - 0.066 13.5 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 PDZ domain Tcp10_C PF07202.13 OWF38138.1 - 2.4e-13 50.4 0.0 0.16 11.9 0.0 5.3 1 1 2 4 4 4 4 T-complex protein 10 C-terminus BTB PF00651.31 OWF38139.1 - 1.3e-20 73.7 0.0 9.8e-20 70.9 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF38139.1 - 3.3e-14 52.8 1.6 2.5e-13 50.0 1.5 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch RRM_1 PF00076.22 OWF38140.1 - 2.7e-19 68.7 0.0 3.7e-13 49.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OWF38140.1 - 0.0046 16.9 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 RL domain DUF1866 PF08952.11 OWF38140.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Kelch_1 PF01344.25 OWF38141.1 - 3.4e-12 45.7 0.6 3.4e-12 45.7 0.6 2.8 3 1 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 OWF38141.1 - 4.4e-08 33.1 2.8 1.1e-06 28.7 1.4 2.9 1 1 1 2 2 2 1 Kelch motif Kelch_2 PF07646.15 OWF38141.1 - 0.021 14.8 2.3 0.067 13.2 1.8 2.2 2 1 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 OWF38141.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF38141.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Aquarius_N PF16399.5 OWF38142.1 - 0 1050.2 7.0 0 1049.9 7.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 OWF38142.1 - 1.2e-27 96.8 0.1 8.6e-27 94.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OWF38142.1 - 2e-26 93.4 0.0 4e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF38142.1 - 1.3e-08 35.3 0.0 2.9e-07 30.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF38142.1 - 6.3e-06 26.0 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 OWF38142.1 - 0.00043 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF38142.1 - 0.0045 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 OWF38142.1 - 0.0068 16.2 0.4 0.015 15.1 0.4 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Parvo_NS1 PF01057.17 OWF38142.1 - 0.0089 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 OWF38142.1 - 0.0096 16.3 0.1 0.034 14.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain DUF2075 PF09848.9 OWF38142.1 - 0.02 14.1 0.2 0.078 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CM_2 PF01817.21 OWF38142.1 - 0.031 14.6 0.2 2.5 8.5 0.0 3.9 4 0 0 4 4 4 0 Chorismate mutase type II UvrD-helicase PF00580.21 OWF38142.1 - 0.034 13.7 0.1 0.21 11.1 0.0 2.4 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 OWF38142.1 - 0.036 14.5 0.0 0.12 12.8 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF38142.1 - 0.043 14.1 0.4 0.5 10.6 0.1 2.6 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 OWF38142.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DnaB_C PF03796.15 OWF38142.1 - 0.11 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 OWF38142.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RecA PF00154.21 OWF38142.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_23 PF13476.6 OWF38142.1 - 1.5 9.3 0.0 1.5 9.3 0.0 2.6 3 1 0 3 3 2 0 AAA domain COR PF16095.5 OWF38143.1 - 9.6e-12 45.1 1.0 2.3e-11 43.9 1.0 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF38143.1 - 1.8e-11 44.3 0.1 3.5e-05 24.0 0.0 3.0 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase PH PF00169.29 OWF38143.1 - 0.00014 22.3 0.3 0.0004 20.9 0.3 1.9 1 0 0 1 1 1 1 PH domain Ras PF00071.22 OWF38143.1 - 0.00015 21.4 0.1 0.11 12.1 0.0 2.9 3 0 0 3 3 3 2 Ras family Trypsin_2 PF13365.6 OWF38143.1 - 0.01 16.7 0.0 0.067 14.1 0.0 2.2 2 0 0 2 2 2 0 Trypsin-like peptidase domain AAA_18 PF13238.6 OWF38143.1 - 0.024 15.2 0.3 1.9 9.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OWF38143.1 - 0.026 14.6 0.0 0.13 12.3 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 OWF38143.1 - 0.05 12.8 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 OWF38143.1 - 0.072 13.6 0.1 0.25 11.9 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Arf PF00025.21 OWF38143.1 - 0.079 12.4 0.1 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 OWF38143.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OWF38143.1 - 0.1 13.0 0.7 0.51 10.7 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OWF38143.1 - 0.1 12.9 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mito_carr PF00153.27 OWF38144.1 - 1.8e-33 114.3 9.0 4.4e-16 58.6 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein RTT107_BRCT_5 PF16770.5 OWF38145.1 - 5.7e-10 39.0 0.3 2.7e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain FHA PF00498.26 OWF38145.1 - 1.4e-08 35.0 0.0 3.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 OWF38145.1 - 4.5e-08 33.4 0.0 4.1e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OWF38145.1 - 4.1e-05 23.5 0.1 0.23 11.4 0.0 2.7 2 0 0 2 2 2 2 twin BRCT domain Yop-YscD_cpl PF16697.5 OWF38145.1 - 0.00015 22.0 0.0 0.00058 20.1 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4423 PF14394.6 OWF38145.1 - 1.3 8.7 5.9 1.2 8.8 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Tim29 PF10171.9 OWF38146.1 - 1.5e-46 158.0 0.1 1.7e-46 157.8 0.1 1.0 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 PA-IIL PF07472.11 OWF38146.1 - 0.18 12.1 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) fn3 PF00041.21 OWF38147.1 - 5.8e-16 58.6 2.7 9e-06 25.9 0.7 4.9 5 0 0 5 5 5 3 Fibronectin type III domain fn3_4 PF16794.5 OWF38147.1 - 3.3e-06 27.0 0.0 0.18 11.7 0.0 3.0 2 0 0 2 2 2 2 Fibronectin-III type domain ig PF00047.25 OWF38147.1 - 0.0009 19.4 0.0 0.0031 17.7 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain IL6Ra-bind PF09240.10 OWF38147.1 - 0.0081 16.6 2.8 0.12 12.8 1.5 3.3 2 1 1 3 3 3 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 OWF38147.1 - 0.13 12.4 1.1 0.69 10.2 0.3 2.7 3 0 0 3 3 3 0 Erythropoietin receptor, ligand binding Ribosomal_L41 PF05162.13 OWF38148.1 - 0.0028 17.7 7.3 11 6.2 0.1 4.9 5 1 1 6 6 6 3 Ribosomal protein L41 ASH PF15780.5 OWF38148.1 - 0.059 13.6 5.5 3.6 7.9 1.0 3.6 1 1 1 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Sushi PF00084.20 OWF38148.1 - 0.48 11.1 12.3 16 6.2 0.1 4.8 3 2 2 5 5 5 0 Sushi repeat (SCR repeat) NB-ARC PF00931.22 OWF38148.1 - 8.4 5.5 6.3 40 3.3 0.3 2.9 1 1 2 3 3 3 0 NB-ARC domain CI-B14_5a PF07347.12 OWF38151.1 - 3.9e-22 78.0 0.1 4.9e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) 7tm_1 PF00001.21 OWF38152.1 - 6.6e-52 176.4 19.5 8.2e-52 176.1 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF38152.1 - 3.3e-10 40.1 13.0 6.5e-10 39.1 13.0 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4156 PF13698.6 OWF38154.1 - 0.007 16.7 5.0 0.011 16.0 1.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4156) DUF2935 PF11155.8 OWF38154.1 - 1.4 9.3 6.7 0.37 11.1 2.7 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF2616 PF11077.8 OWF38155.1 - 3.6e-10 39.8 32.7 0.056 13.2 0.4 6.8 1 1 5 6 6 6 6 Protein of unknown function (DUF2616) DUF2591 PF10765.9 OWF38155.1 - 4.6e-05 23.7 2.7 4.6 7.6 0.1 4.4 1 1 3 5 5 5 3 Protein of unknown function (DUF2591) Reductase_C PF14759.6 OWF38155.1 - 0.0017 18.9 2.0 33 5.1 0.0 4.7 3 1 2 5 5 5 0 Reductase C-terminal DUF4573 PF15140.6 OWF38155.1 - 0.0031 17.3 0.2 8.4 6.2 0.0 3.2 1 1 1 3 3 3 2 Domain of unknown function (DUF4573) HTH_Tnp_Tc3_2 PF01498.18 OWF38155.1 - 0.014 15.6 0.3 0.88 9.9 0.0 3.5 2 0 0 2 2 2 0 Transposase PrkA PF06798.12 OWF38155.1 - 0.13 11.8 4.1 40 3.7 0.0 4.1 1 1 2 4 4 4 0 PrkA serine protein kinase C-terminal domain DUF1280 PF06918.14 OWF38155.1 - 0.18 11.3 14.2 7.2 6.1 0.3 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1280) DUF2616 PF11077.8 OWF38156.1 - 6.2e-13 48.8 90.7 0.019 14.6 2.9 14.7 1 1 14 15 15 15 12 Protein of unknown function (DUF2616) DUF4573 PF15140.6 OWF38156.1 - 1.3e-11 44.6 0.2 0.081 12.7 0.1 5.8 1 1 6 7 7 7 7 Domain of unknown function (DUF4573) DUF2591 PF10765.9 OWF38156.1 - 7.5e-07 29.4 20.2 8.6 6.7 0.3 9.9 1 1 6 8 8 8 4 Protein of unknown function (DUF2591) PrmC_N PF17827.1 OWF38156.1 - 0.00032 21.2 3.7 47 4.7 0.0 7.6 4 2 5 9 9 9 0 PrmC N-terminal domain DUF866 PF05907.13 OWF38157.1 - 3.5e-55 186.2 0.2 3.9e-55 186.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4566 PF15130.6 OWF38158.1 - 3.6e-127 422.3 1.1 4.1e-127 422.2 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) HPS6 PF15702.5 OWF38159.1 - 1.2e-42 145.9 9.6 1.4e-41 142.4 9.6 1.9 1 1 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein DPPIV_N PF00930.21 OWF38159.1 - 0.092 11.5 0.0 0.26 10.0 0.0 1.7 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region UPF0004 PF00919.20 OWF38160.1 - 5.2e-23 81.0 0.0 1.6e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 OWF38160.1 - 9.4e-16 58.6 0.0 1.7e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 OWF38160.1 - 6e-06 26.2 0.1 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 TRAM domain TraT PF05818.12 OWF38160.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein TRAM_2 PF18693.1 OWF38160.1 - 0.018 15.2 0.2 0.064 13.4 0.2 2.0 1 1 0 1 1 1 0 TRAM domain ICL PF00463.21 OWF38160.1 - 0.073 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Isocitrate lyase family Ank_2 PF12796.7 OWF38161.1 - 8.8e-12 45.5 0.1 3.8e-06 27.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38161.1 - 2.9e-11 43.6 0.1 5.7e-05 23.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF38161.1 - 3e-10 40.2 0.3 1.4e-06 28.4 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF38161.1 - 2.3e-08 34.1 0.2 0.53 10.8 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OWF38161.1 - 8.5e-07 28.8 0.4 0.32 11.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Jak1_Phl PF17887.1 OWF38161.1 - 0.5 10.3 3.5 0.95 9.4 0.0 2.8 3 0 0 3 3 3 0 Jak1 pleckstrin homology-like domain Forkhead PF00250.18 OWF38162.1 - 1e-32 112.2 0.0 1.8e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain RRM_5 PF13893.6 OWF38163.1 - 2.2e-45 153.3 4.1 5.5e-33 113.2 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OWF38163.1 - 8.8e-33 112.0 1.0 8.5e-08 31.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OWF38163.1 - 6.6e-12 45.5 0.0 2e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 OWF38163.1 - 2.7e-07 30.4 0.2 0.0016 18.3 0.0 3.8 4 0 0 4 4 4 2 Occluded RNA-recognition motif PcrB PF01884.17 OWF38164.1 - 0.18 11.2 1.0 0.21 11.0 0.1 1.5 2 0 0 2 2 2 0 PcrB family Cyto_heme_lyase PF01265.17 OWF38165.1 - 9.1e-67 225.7 17.6 4.9e-66 223.3 17.6 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Kazal_2 PF07648.15 OWF38165.1 - 0.15 12.3 0.4 2.2 8.5 0.1 2.4 1 1 1 2 2 2 0 Kazal-type serine protease inhibitor domain zf_PR_Knuckle PF18445.1 OWF38165.1 - 7.6 6.4 8.9 2.6 7.9 0.4 3.0 3 0 0 3 3 3 0 PR zinc knuckle motif F-box-like PF12937.7 OWF38166.1 - 2.5e-11 43.3 2.6 2.5e-11 43.3 2.6 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 OWF38166.1 - 1.6e-10 40.6 5.7 3.9e-09 36.2 1.1 3.5 2 1 1 3 3 3 1 F-box domain LRR_4 PF12799.7 OWF38166.1 - 9.4e-08 32.2 6.9 0.0014 19.0 0.5 4.9 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF38166.1 - 4.5e-07 29.4 10.6 1.3 9.2 0.0 6.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 OWF38166.1 - 0.03 14.8 10.6 12 7.0 0.4 6.6 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 OWF38166.1 - 0.66 9.8 7.8 6.5 6.6 0.1 4.5 4 2 1 5 5 5 0 Leucine rich repeat hEGF PF12661.7 OWF38167.1 - 0.51 11.1 7.7 11 6.8 0.4 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 OWF38167.1 - 5.9 7.3 8.4 9.2 6.7 4.9 2.6 1 1 1 2 2 2 0 EGF-like domain TIR PF01582.20 OWF38168.1 - 1.9e-21 76.6 0.1 3.1e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF38168.1 - 4.7e-17 62.7 0.0 8.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 TIR domain EutA PF06277.11 OWF38168.1 - 0.0063 15.4 0.2 0.0088 14.9 0.2 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA EGF PF00008.27 OWF38169.1 - 2.4e-06 27.7 37.1 0.0044 17.3 4.4 3.8 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 OWF38169.1 - 0.00046 20.7 12.5 0.25 12.0 0.1 4.2 3 1 0 3 3 3 3 Human growth factor-like EGF EGF_3 PF12947.7 OWF38169.1 - 0.0073 16.5 20.8 0.0083 16.3 0.5 3.7 3 1 0 3 3 3 2 EGF domain EGF_2 PF07974.13 OWF38169.1 - 0.022 15.1 39.8 0.031 14.7 7.6 4.0 4 1 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 OWF38169.1 - 0.48 10.6 30.7 3.2 8.0 11.5 3.4 2 1 1 3 3 3 0 Laminin EGF domain DSL PF01414.19 OWF38169.1 - 7.5 6.9 27.7 1.9 8.8 9.4 2.8 2 1 0 2 2 2 0 Delta serrate ligand cobW PF02492.19 OWF38170.1 - 6.9e-51 172.3 0.4 1e-50 171.7 0.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OWF38170.1 - 1.5e-17 63.2 0.0 2.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OWF38170.1 - 2.3e-06 27.6 0.4 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 OWF38170.1 - 0.01 15.8 0.4 0.024 14.6 0.0 1.8 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OWF38170.1 - 0.011 16.1 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF38170.1 - 0.013 16.1 1.6 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 OWF38170.1 - 0.014 14.3 0.8 0.93 8.4 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OWF38170.1 - 0.023 15.3 0.0 0.057 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OWF38170.1 - 0.034 14.2 0.1 0.22 11.6 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF38170.1 - 0.037 13.8 1.6 3.9 7.2 0.2 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 OWF38170.1 - 0.048 13.7 0.2 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OWF38170.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 OWF38170.1 - 5.6 7.4 9.7 59 4.1 9.7 2.2 1 1 0 1 1 1 0 AAA domain rve PF00665.26 OWF38171.1 - 5.4e-19 68.5 0.0 9.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OWF38171.1 - 5.8e-15 55.1 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OWF38171.1 - 0.00021 21.0 0.0 0.00051 19.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 OWF38171.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 DDE domain Peptidase_M3 PF01432.20 OWF38172.1 - 2.1e-151 505.3 0.8 2.1e-151 505.3 0.8 1.8 2 0 0 2 2 2 1 Peptidase family M3 Patched PF02460.18 OWF38173.1 - 1.8e-67 228.1 12.4 3.9e-38 131.1 0.0 2.0 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 OWF38173.1 - 1e-37 129.4 0.4 1e-37 129.4 0.4 4.1 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation AAA PF00004.29 OWF38174.1 - 7.9e-96 317.5 0.0 1.3e-46 158.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF38174.1 - 1.2e-26 92.2 6.2 7.8e-13 48.0 0.4 3.0 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 OWF38174.1 - 9e-22 77.1 0.4 1.2e-20 73.5 0.7 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 OWF38174.1 - 8.4e-14 51.6 0.0 2e-05 24.4 0.0 3.4 2 2 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OWF38174.1 - 1.2e-11 45.3 4.1 0.00022 21.7 0.1 4.4 4 2 0 4 4 2 2 AAA ATPase domain AAA_33 PF13671.6 OWF38174.1 - 1.1e-10 41.8 0.0 4.4e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 OWF38174.1 - 3.7e-10 39.4 0.0 7.7e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 OWF38174.1 - 6.3e-10 39.4 0.0 4.6e-05 23.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OWF38174.1 - 1.1e-09 38.5 0.1 0.00024 21.1 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF38174.1 - 2.1e-09 37.8 0.2 0.018 15.3 0.1 3.7 2 2 0 2 2 2 2 AAA domain Vps4_C PF09336.10 OWF38174.1 - 2.6e-08 33.7 0.6 0.00018 21.4 0.1 2.8 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 OWF38174.1 - 3.5e-08 33.0 0.3 0.0039 16.4 0.0 2.7 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_18 PF13238.6 OWF38174.1 - 6.6e-08 33.2 0.0 0.018 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OWF38174.1 - 9e-08 32.5 0.0 0.0065 16.9 0.0 3.3 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.21 OWF38174.1 - 5.4e-07 29.2 0.2 0.02 14.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OWF38174.1 - 6.4e-07 29.3 0.1 0.059 13.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 OWF38174.1 - 1.8e-06 28.0 0.0 0.061 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OWF38174.1 - 4.1e-06 27.1 0.1 0.17 12.1 0.0 3.1 4 0 0 4 4 2 2 AAA domain Parvo_NS1 PF01057.17 OWF38174.1 - 4.8e-06 25.9 0.1 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 OWF38174.1 - 5.3e-06 26.1 0.0 0.052 13.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 OWF38174.1 - 5.5e-06 26.9 0.0 0.014 15.9 0.0 3.5 2 1 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 OWF38174.1 - 8.9e-06 25.8 0.5 0.27 11.1 0.0 3.9 4 1 1 5 5 3 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 OWF38174.1 - 1.1e-05 25.4 0.0 0.064 13.1 0.0 2.7 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_25 PF13481.6 OWF38174.1 - 1.5e-05 24.7 0.4 1.3 8.6 0.0 3.5 2 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OWF38174.1 - 2.8e-05 24.0 0.2 0.097 12.4 0.0 3.0 3 1 0 3 3 3 2 AAA domain TsaE PF02367.17 OWF38174.1 - 5.6e-05 23.1 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OWF38174.1 - 0.0001 22.7 0.0 1 9.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 OWF38174.1 - 0.00011 21.4 0.0 0.053 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase PF06745.13 OWF38174.1 - 0.00014 21.3 0.3 2.1 7.6 0.0 3.3 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 OWF38174.1 - 0.00015 21.5 0.0 0.67 9.6 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OWF38174.1 - 0.0002 21.2 0.0 0.0023 17.7 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OWF38174.1 - 0.00023 20.5 0.0 0.23 10.6 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 OWF38174.1 - 0.00033 20.6 0.1 0.27 11.1 0.0 3.2 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 OWF38174.1 - 0.00046 20.2 0.0 0.076 13.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OWF38174.1 - 0.00059 19.3 0.0 0.92 8.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.12 OWF38174.1 - 0.0013 18.0 0.0 0.57 9.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.11 OWF38174.1 - 0.0015 18.4 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OWF38174.1 - 0.0019 17.5 0.0 0.72 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 OWF38174.1 - 0.0036 17.1 0.1 3.5 7.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 OWF38174.1 - 0.0048 17.0 0.0 3.2 7.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 OWF38174.1 - 0.011 15.6 0.0 0.7 9.8 0.0 2.5 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 OWF38174.1 - 0.018 15.4 2.6 4.2 7.7 0.3 3.2 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 OWF38174.1 - 0.024 14.3 0.2 3.3 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OWF38174.1 - 0.029 14.3 0.2 5.7 6.8 0.0 3.2 3 0 0 3 3 3 0 NTPase Cytidylate_kin PF02224.18 OWF38174.1 - 0.043 13.6 0.0 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 OWF38174.1 - 0.047 13.8 0.0 8.6 6.5 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.9 OWF38174.1 - 0.059 13.1 0.0 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 OWF38174.1 - 0.1 12.2 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 OWF38174.1 - 0.13 11.5 0.1 4.6 6.4 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain Zot PF05707.12 OWF38174.1 - 0.13 11.9 0.0 1.9 8.1 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Vps55 PF04133.14 OWF38175.1 - 1.9e-40 137.5 11.2 2.1e-40 137.3 11.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Bax1-I PF01027.20 OWF38175.1 - 0.032 14.1 10.9 0.036 13.9 10.9 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 OWF38175.1 - 0.67 8.2 9.5 0.79 7.9 9.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CCB1 PF12046.8 OWF38175.1 - 0.7 9.2 8.2 2.3 7.5 1.1 2.1 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Peptidase_U4 PF03419.13 OWF38175.1 - 8.9 5.5 9.5 11 5.2 9.5 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA VWA_2 PF13519.6 OWF38176.1 - 0.00038 21.1 0.0 0.00073 20.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Membralin PF09746.9 OWF38177.1 - 4.4e-166 552.6 3.7 4.4e-166 552.6 3.7 2.1 2 1 0 2 2 2 1 Tumour-associated protein Mt_ATP-synt_D PF05873.12 OWF38177.1 - 0.23 11.3 2.5 0.19 11.6 0.6 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) LIM PF00412.22 OWF38178.1 - 2.5e-08 34.0 4.6 5.2e-08 33.0 4.6 1.6 1 0 0 1 1 1 1 LIM domain DUF2034 PF10356.9 OWF38178.1 - 4.5 6.7 9.0 2.2 7.7 6.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) Dicty_CAR PF05462.11 OWF38179.1 - 2.2e-07 30.3 9.7 2.8e-07 30.0 9.7 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Prominin PF05478.11 OWF38179.1 - 3.3 5.5 8.4 6.1 4.7 8.4 1.3 1 0 0 1 1 1 0 Prominin zf-B_box PF00643.24 OWF38180.1 - 2e-06 27.9 2.5 4.4e-06 26.8 2.5 1.6 1 0 0 1 1 1 1 B-box zinc finger SGL PF08450.12 OWF38180.1 - 0.0013 18.4 2.1 0.3 10.6 0.1 3.0 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF38180.1 - 0.0016 18.3 1.1 6 7.1 0.0 4.2 4 0 0 4 4 4 2 NHL repeat zf-UBR PF02207.20 OWF38180.1 - 0.0023 18.1 2.6 0.0074 16.4 2.6 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) P35 PF02331.15 OWF38180.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Apoptosis preventing protein Reg_prop PF07494.11 OWF38180.1 - 0.054 13.7 0.6 8.8 6.9 0.1 4.0 3 0 0 3 3 3 0 Two component regulator propeller DLP_helical PF18709.1 OWF38180.1 - 0.077 12.2 1.3 0.11 11.7 1.3 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Endotoxin_N PF03945.14 OWF38180.1 - 0.08 12.7 0.3 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain ZZ PF00569.17 OWF38180.1 - 0.11 12.4 4.5 0.07 13.0 2.1 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type Phage_sheath_1N PF17481.2 OWF38181.1 - 8.3 7.0 8.8 3.9e+02 1.6 8.2 2.9 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Ub-Mut7C PF14451.6 OWF38182.1 - 0.023 14.5 6.8 38 4.2 0.0 6.0 1 1 6 9 9 9 0 Mut7-C ubiquitin Ag332 PF04671.12 OWF38182.1 - 0.03 14.2 1.1 13 5.9 0.1 3.0 2 0 0 2 2 2 0 Erythrocyte membrane-associated giant protein antigen 332 DUF4491 PF14898.6 OWF38182.1 - 0.16 12.4 11.9 2 8.9 0.4 4.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4491) PSI_integrin PF17205.3 OWF38182.1 - 0.58 10.0 21.6 40 4.0 0.5 8.2 3 3 4 7 7 7 0 Integrin plexin domain Nucleoporin_FG PF13634.6 OWF38182.1 - 0.87 10.5 9.3 1.5 9.7 9.3 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region SWM_repeat PF13753.6 OWF38182.1 - 2.6 8.2 21.0 1.2e+02 2.9 0.1 7.8 1 1 6 9 9 9 0 Putative flagellar system-associated repeat Sulfotransfer_1 PF00685.27 OWF38183.1 - 2.8e-26 92.6 0.1 3.9e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF38183.1 - 6.1e-11 43.1 0.0 1.1e-05 25.9 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF38183.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Methyltransf_11 PF08241.12 OWF38184.1 - 1.1e-05 25.9 0.0 1.7e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF38184.1 - 1.2e-05 24.7 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OWF38184.1 - 0.00059 20.5 0.0 0.0012 19.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF38185.1 - 2.1e-11 44.4 0.0 3.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF38185.1 - 4.7e-11 43.2 0.0 7.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF38185.1 - 1.4e-09 38.0 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF38185.1 - 4.7e-07 29.4 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OWF38185.1 - 4.1e-06 27.5 0.0 6.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 OWF38185.1 - 0.00064 19.3 0.0 0.00086 18.9 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_31 PF13847.6 OWF38185.1 - 0.00078 19.3 0.0 0.0015 18.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 OWF38185.1 - 0.012 14.2 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 OWF38185.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 OWF38185.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LPMO_10 PF03067.15 OWF38186.1 - 6.9e-31 108.4 0.6 6.9e-31 108.4 0.6 2.1 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Mitofilin PF09731.9 OWF38186.1 - 2 7.1 4.5 2.6 6.8 4.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Telomerase_RBD PF12009.8 OWF38187.1 - 8.5e-25 87.4 4.1 8.5e-25 87.4 4.1 2.4 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OWF38187.1 - 4.8e-10 39.3 0.4 2.2e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) VWD PF00094.25 OWF38189.1 - 8.9e-13 48.8 0.3 3.1e-12 47.0 0.3 2.0 1 1 0 1 1 1 1 von Willebrand factor type D domain VWD PF00094.25 OWF38190.1 - 3.5e-13 50.1 0.6 1.5e-12 48.0 0.6 2.1 1 1 0 1 1 1 1 von Willebrand factor type D domain DUF2944 PF11161.8 OWF38190.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) VWD PF00094.25 OWF38191.1 - 6.7e-13 49.2 1.3 6.7e-13 49.2 1.3 2.6 2 1 0 2 2 2 1 von Willebrand factor type D domain EGF_2 PF07974.13 OWF38191.1 - 0.014 15.8 13.4 0.014 15.8 13.4 6.7 5 1 1 6 6 6 0 EGF-like domain ThaI PF15514.6 OWF38191.1 - 0.21 11.2 0.1 0.41 10.3 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease ThaI Lectin_C PF00059.21 OWF38192.1 - 4e-16 59.7 0.4 1e-15 58.4 0.4 1.7 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF38192.1 - 0.0097 15.9 3.8 0.0097 15.9 3.8 1.7 1 1 0 1 1 1 1 PAN domain TIL PF01826.17 OWF38192.1 - 0.019 15.2 1.0 0.059 13.6 1.0 1.8 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF3510 PF12022.8 OWF38193.1 - 0.081 13.3 0.0 0.089 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) MscS_porin PF12795.7 OWF38194.1 - 4.1e-15 56.0 16.6 2.4e-06 27.3 1.9 3.0 1 1 2 3 3 3 3 Mechanosensitive ion channel porin domain Spc7 PF08317.11 OWF38194.1 - 1.7e-13 50.2 31.8 3.8e-08 32.6 11.2 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OWF38194.1 - 8.4e-13 48.6 3.7 1.6e-06 28.2 0.5 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 OWF38194.1 - 8.6e-12 45.2 22.3 6.7e-05 22.9 8.4 3.1 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 OWF38194.1 - 1.4e-11 44.6 40.7 1e-07 32.1 17.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 OWF38194.1 - 2.3e-11 43.9 18.7 4.1e-06 27.1 3.3 3.4 1 1 1 2 2 2 2 Snapin/Pallidin Erp_C PF06780.11 OWF38194.1 - 2.4e-10 40.6 25.9 0.0078 16.2 1.9 5.7 1 1 4 5 5 5 4 Erp protein C-terminus KxDL PF10241.9 OWF38194.1 - 4.1e-10 39.8 18.3 0.0048 17.1 0.4 3.9 1 1 3 4 4 4 4 Uncharacterized conserved protein IFT57 PF10498.9 OWF38194.1 - 6.2e-10 38.6 14.4 5.6e-06 25.6 2.3 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.20 OWF38194.1 - 1.1e-09 38.2 21.0 0.0059 16.5 0.7 3.8 1 1 4 5 5 5 5 Prefoldin subunit Nup54 PF13874.6 OWF38194.1 - 1.3e-09 38.3 24.0 6.9e-07 29.5 10.5 2.4 1 1 1 2 2 2 2 Nucleoporin complex subunit 54 NPV_P10 PF05531.12 OWF38194.1 - 1.4e-09 38.3 9.9 0.012 16.1 0.4 3.7 1 1 2 3 3 3 3 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OWF38194.1 - 2e-09 37.5 9.8 7.6e-06 26.0 5.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Sec2p PF06428.11 OWF38194.1 - 2.7e-09 36.9 25.3 0.0087 16.0 0.9 4.2 1 1 3 4 4 4 4 GDP/GTP exchange factor Sec2p PspA_IM30 PF04012.12 OWF38194.1 - 2.9e-09 36.9 10.4 0.0012 18.4 0.6 3.0 1 1 2 3 3 3 3 PspA/IM30 family Atg14 PF10186.9 OWF38194.1 - 3.5e-09 36.2 24.8 4.2e-06 26.1 14.1 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 OWF38194.1 - 3.5e-09 36.6 17.2 0.0019 18.0 0.9 3.5 1 1 2 3 3 3 3 Phage minor structural protein GP20 FlaC_arch PF05377.11 OWF38194.1 - 4.1e-09 36.7 20.1 0.02 15.3 1.7 4.2 1 1 3 4 4 4 3 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 OWF38194.1 - 4.2e-09 36.4 14.6 2.7e-07 30.5 14.6 2.0 1 1 0 1 1 1 1 Exonuclease VII, large subunit TACC_C PF05010.14 OWF38194.1 - 5e-09 36.2 14.4 0.0036 17.1 0.7 2.9 1 1 2 3 3 3 3 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 OWF38194.1 - 1.1e-08 34.7 31.7 2.5e-05 23.7 12.4 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 OWF38194.1 - 2e-08 34.4 14.4 9.3e-05 22.5 7.0 2.4 1 1 1 2 2 2 2 Laminin Domain II Matrilin_ccoil PF10393.9 OWF38194.1 - 2.6e-08 33.6 28.6 0.14 12.1 0.6 6.4 1 1 4 6 6 6 2 Trimeric coiled-coil oligomerisation domain of matrilin TolA_bind_tri PF16331.5 OWF38194.1 - 3.7e-08 33.3 21.5 0.049 13.7 3.4 3.8 1 1 3 4 4 4 4 TolA binding protein trimerisation HOOK PF05622.12 OWF38194.1 - 4.3e-08 31.8 24.7 1.3e-05 23.6 13.3 2.0 1 1 1 2 2 2 2 HOOK protein DUF4795 PF16043.5 OWF38194.1 - 4.4e-08 33.0 17.9 1.9e-07 30.9 17.9 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) XhlA PF10779.9 OWF38194.1 - 5.5e-08 32.9 27.1 0.02 15.1 2.6 4.1 1 1 3 4 4 4 4 Haemolysin XhlA FPP PF05911.11 OWF38194.1 - 9.9e-08 30.7 19.2 1.2e-06 27.1 19.0 1.9 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil TMPIT PF07851.13 OWF38194.1 - 1.1e-07 31.5 8.0 0.00028 20.3 3.4 2.0 1 1 1 2 2 2 2 TMPIT-like protein EzrA PF06160.12 OWF38194.1 - 1.2e-07 30.3 14.6 2.7e-05 22.6 4.4 1.9 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DHR10 PF18595.1 OWF38194.1 - 1.7e-07 31.3 27.5 0.013 15.5 6.2 3.0 1 1 2 3 3 3 3 Designed helical repeat protein 10 domain AAA_13 PF13166.6 OWF38194.1 - 1.8e-07 30.2 4.1 2.2e-07 30.0 4.1 1.0 1 0 0 1 1 1 1 AAA domain MCC-bdg_PDZ PF10506.9 OWF38194.1 - 1.9e-07 31.0 28.2 0.21 11.6 2.1 6.1 1 1 5 6 6 6 2 PDZ domain of MCC-2 bdg protein for Usher syndrome HemX PF04375.14 OWF38194.1 - 2.4e-07 30.4 6.0 0.0032 16.8 2.1 2.6 1 1 1 2 2 2 2 HemX, putative uroporphyrinogen-III C-methyltransferase Spectrin PF00435.21 OWF38194.1 - 3.1e-07 30.8 25.0 6.5e-05 23.4 8.3 3.3 1 1 2 3 3 2 2 Spectrin repeat UPF0184 PF03670.13 OWF38194.1 - 3.4e-07 30.5 28.8 0.17 12.3 5.0 4.9 1 1 4 5 5 5 3 Uncharacterised protein family (UPF0184) HR1 PF02185.16 OWF38194.1 - 3.8e-07 30.1 35.6 0.047 13.8 4.1 5.3 1 1 4 5 5 5 2 Hr1 repeat DASH_Hsk3 PF08227.11 OWF38194.1 - 3.8e-07 30.3 13.1 0.36 11.2 0.2 6.0 3 3 3 7 7 6 1 DASH complex subunit Hsk3 like FliJ PF02050.16 OWF38194.1 - 4e-07 30.3 6.8 0.00038 20.7 2.3 2.4 1 1 1 2 2 2 2 Flagellar FliJ protein HalX PF08663.10 OWF38194.1 - 4.1e-07 30.2 36.7 0.31 11.4 3.2 6.2 1 1 4 5 5 5 1 HalX domain Occludin_ELL PF07303.13 OWF38194.1 - 4.3e-07 30.6 16.4 0.00081 20.1 5.1 3.5 1 1 2 3 3 3 2 Occludin homology domain ABC_tran_CTD PF16326.5 OWF38194.1 - 5.4e-07 29.8 17.6 0.0092 16.2 3.1 3.7 1 1 3 4 4 4 4 ABC transporter C-terminal domain DUF745 PF05335.13 OWF38194.1 - 6.1e-07 29.3 4.4 0.0026 17.5 0.4 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF745) DUF4201 PF13870.6 OWF38194.1 - 6.3e-07 29.3 24.2 0.00061 19.6 11.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) BST2 PF16716.5 OWF38194.1 - 6.7e-07 29.8 18.3 0.002 18.7 2.8 3.3 1 1 2 3 3 3 3 Bone marrow stromal antigen 2 CREPT PF16566.5 OWF38194.1 - 1.3e-06 28.7 16.7 0.021 15.0 5.5 3.0 1 1 2 3 3 3 2 Cell-cycle alteration and expression-elevated protein in tumour Filament PF00038.21 OWF38194.1 - 1.3e-06 28.2 16.6 7.9e-06 25.7 16.6 1.9 1 1 0 1 1 1 1 Intermediate filament protein RmuC PF02646.16 OWF38194.1 - 1.6e-06 27.5 6.0 0.088 11.9 0.2 3.0 1 1 2 3 3 3 3 RmuC family TMF_TATA_bd PF12325.8 OWF38194.1 - 1.9e-06 28.1 28.4 0.0085 16.3 12.1 3.4 1 1 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Mod_r PF07200.13 OWF38194.1 - 2.1e-06 27.9 19.0 0.0037 17.4 10.4 2.6 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Fmp27_WPPW PF10359.9 OWF38194.1 - 2.2e-06 26.8 17.2 0.0034 16.3 4.8 2.1 1 1 1 2 2 2 2 RNA pol II promoter Fmp27 protein domain LXG PF04740.12 OWF38194.1 - 2.6e-06 27.3 8.9 0.034 13.9 4.1 4.1 1 1 1 2 2 2 1 LXG domain of WXG superfamily DUF2203 PF09969.9 OWF38194.1 - 3.3e-06 27.8 7.8 0.002 18.9 3.5 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 OWF38194.1 - 3.7e-06 27.1 21.5 0.44 10.8 2.5 4.0 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 ADIP PF11559.8 OWF38194.1 - 3.7e-06 27.1 18.0 0.0038 17.3 5.6 2.7 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 OWF38194.1 - 3.9e-06 27.2 29.8 0.0037 17.5 6.3 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 OWF38194.1 - 4.3e-06 27.0 14.6 0.011 16.1 7.4 3.9 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) CLZ PF16526.5 OWF38194.1 - 4.9e-06 26.8 27.9 0.038 14.4 5.6 4.2 1 1 2 3 3 3 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 OWF38194.1 - 5.4e-06 25.9 12.2 0.0012 18.2 5.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) FliD_N PF02465.18 OWF38194.1 - 6e-06 26.9 7.5 0.57 10.9 0.5 3.8 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF3584 PF12128.8 OWF38194.1 - 8.1e-06 23.7 16.0 0.0006 17.5 8.5 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) FapA PF03961.13 OWF38194.1 - 8.2e-06 24.7 16.8 0.00072 18.3 4.2 2.0 1 1 1 2 2 2 2 Flagellar Assembly Protein A YtxH PF12732.7 OWF38194.1 - 9.3e-06 26.1 9.6 23 5.6 9.6 4.0 1 1 0 1 1 1 0 YtxH-like protein Fib_alpha PF08702.10 OWF38194.1 - 1.1e-05 25.7 11.3 0.00045 20.4 5.0 2.4 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family FH2 PF02181.23 OWF38194.1 - 1.1e-05 24.7 15.6 0.00048 19.4 2.9 2.2 1 1 1 2 2 2 2 Formin Homology 2 Domain SKA2 PF16740.5 OWF38194.1 - 1.2e-05 25.0 15.3 0.023 14.5 4.9 3.9 1 1 2 3 3 3 2 Spindle and kinetochore-associated protein 2 Cast PF10174.9 OWF38194.1 - 1.3e-05 23.7 22.9 1.6e-05 23.4 22.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone FliD_C PF07195.12 OWF38194.1 - 1.4e-05 24.6 9.2 0.098 12.1 0.2 3.2 1 1 2 3 3 3 2 Flagellar hook-associated protein 2 C-terminus DUF2730 PF10805.8 OWF38194.1 - 1.6e-05 24.9 16.4 0.059 13.5 2.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF2730) PRKG1_interact PF15898.5 OWF38194.1 - 1.8e-05 25.6 24.3 0.039 14.9 5.7 3.9 1 1 1 3 3 3 1 cGMP-dependent protein kinase interacting domain DUF812 PF05667.11 OWF38194.1 - 1.8e-05 23.9 14.0 5.6e-05 22.2 14.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF1970 PF09301.10 OWF38194.1 - 2.2e-05 24.7 5.9 8.9 6.6 0.1 5.4 1 1 3 4 4 4 0 Domain of unknown function (DUF1970) DASH_Duo1 PF08651.10 OWF38194.1 - 2.5e-05 24.0 3.1 1.9 8.3 0.1 3.8 1 1 3 4 4 4 0 DASH complex subunit Duo1 DivIVA PF05103.13 OWF38194.1 - 3.4e-05 23.9 15.4 0.066 13.3 1.1 3.5 1 1 2 3 3 3 1 DivIVA protein BLOC1_2 PF10046.9 OWF38194.1 - 3.4e-05 24.0 12.4 0.21 11.9 0.8 3.5 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.14 OWF38194.1 - 3.5e-05 23.7 17.3 0.35 10.8 1.3 3.8 1 1 3 4 4 4 3 Sec8 exocyst complex component specific domain Nup88 PF10168.9 OWF38194.1 - 3.7e-05 21.8 10.4 5.2e-05 21.3 10.4 1.2 1 0 0 1 1 1 1 Nuclear pore component Prefoldin PF02996.17 OWF38194.1 - 4.1e-05 23.5 19.1 0.52 10.2 0.2 4.8 1 1 4 5 5 5 1 Prefoldin subunit SesA PF17107.5 OWF38194.1 - 4.1e-05 23.7 9.6 0.046 13.9 1.7 2.7 1 1 1 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases Tropomyosin_1 PF12718.7 OWF38194.1 - 4.2e-05 23.7 23.6 0.00023 21.3 23.5 2.2 1 1 0 1 1 1 1 Tropomyosin like DUF948 PF06103.11 OWF38194.1 - 4.3e-05 23.7 1.0 0.095 13.0 1.0 3.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Myosin_tail_1 PF01576.19 OWF38194.1 - 5.5e-05 21.2 23.1 8e-05 20.7 23.1 1.2 1 0 0 1 1 1 1 Myosin tail Wtap PF17098.5 OWF38194.1 - 5.5e-05 23.1 18.7 0.061 13.2 1.2 3.3 1 1 2 3 3 3 2 WTAP/Mum2p family MAD PF05557.13 OWF38194.1 - 5.6e-05 21.7 17.2 7.2e-05 21.4 17.2 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Bacillus_HBL PF05791.11 OWF38194.1 - 5.8e-05 23.0 7.2 0.036 13.9 2.1 2.3 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) EMP24_GP25L PF01105.24 OWF38194.1 - 6.6e-05 22.9 14.6 0.17 11.8 0.7 3.1 1 1 2 3 3 3 2 emp24/gp25L/p24 family/GOLD Mce4_CUP1 PF11887.8 OWF38194.1 - 7.2e-05 22.4 1.5 0.021 14.3 0.2 2.1 1 1 1 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative GrpE PF01025.19 OWF38194.1 - 7.5e-05 22.4 15.6 0.13 11.9 0.8 3.1 1 1 2 3 3 3 2 GrpE TBCA PF02970.16 OWF38194.1 - 8e-05 22.9 16.8 0.077 13.3 3.6 3.5 1 1 2 3 3 3 2 Tubulin binding cofactor A Rx_N PF18052.1 OWF38194.1 - 8.5e-05 22.8 22.7 0.66 10.3 3.4 4.3 1 1 2 4 4 4 0 Rx N-terminal domain Flagellin_C PF00700.21 OWF38194.1 - 8.7e-05 22.8 3.3 5 7.6 0.1 3.6 1 1 3 4 4 4 0 Bacterial flagellin C-terminal helical region RPW8 PF05659.11 OWF38194.1 - 0.00011 22.0 16.2 0.28 10.9 1.9 3.2 1 1 1 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Muted PF14942.6 OWF38194.1 - 0.00011 22.6 12.2 0.022 15.1 5.9 2.8 1 1 2 3 3 3 2 Organelle biogenesis, Muted-like protein Uso1_p115_C PF04871.13 OWF38194.1 - 0.00011 22.5 25.2 1 9.7 25.2 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 OWF38194.1 - 0.00011 22.3 22.2 0.0042 17.2 22.2 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus SKA1 PF07160.12 OWF38194.1 - 0.00013 21.9 10.1 0.31 10.9 0.7 3.0 1 1 2 3 3 3 1 Spindle and kinetochore-associated protein 1 DUF4200 PF13863.6 OWF38194.1 - 0.00014 22.3 24.8 0.0013 19.1 6.5 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) YabA PF06156.13 OWF38194.1 - 0.00014 22.4 13.2 0.23 12.1 2.1 3.1 1 1 2 3 3 3 1 Initiation control protein YabA Vps52 PF04129.12 OWF38194.1 - 0.00017 20.5 12.9 0.00078 18.3 1.2 2.9 1 1 2 3 3 3 1 Vps52 / Sac2 family Med14 PF08638.11 OWF38194.1 - 0.00017 21.1 0.3 1.1 8.6 0.0 3.0 1 1 2 3 3 3 0 Mediator complex subunit MED14 Fez1 PF06818.15 OWF38194.1 - 0.00018 22.0 20.8 0.0048 17.4 20.7 2.0 1 1 0 1 1 1 1 Fez1 Seryl_tRNA_N PF02403.22 OWF38194.1 - 0.00021 21.5 15.0 0.93 9.8 1.1 3.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 OWF38194.1 - 0.00022 21.7 28.1 0.03 14.9 15.5 2.4 1 1 1 2 2 2 2 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 OWF38194.1 - 0.00024 21.6 20.7 0.22 12.2 8.2 3.0 1 1 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 WXG100 PF06013.12 OWF38194.1 - 0.00026 21.2 1.0 6.1 7.1 0.3 4.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Tropomyosin PF00261.20 OWF38194.1 - 0.00026 20.4 24.9 0.00045 19.7 24.9 1.4 1 1 0 1 1 1 1 Tropomyosin Baculo_p24 PF05073.12 OWF38194.1 - 0.00027 20.8 4.0 0.075 12.8 1.3 2.2 1 1 1 2 2 2 2 Baculovirus P24 capsid protein DUF3829 PF12889.7 OWF38194.1 - 0.00027 20.5 1.0 0.0055 16.2 1.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) ZapB PF06005.12 OWF38194.1 - 0.00028 21.3 24.4 0.2 12.1 3.3 3.1 1 1 2 3 3 3 2 Cell division protein ZapB YscO PF07321.12 OWF38194.1 - 0.00029 20.8 19.1 0.26 11.3 1.7 3.1 1 1 2 3 3 3 2 Type III secretion protein YscO Laminin_I PF06008.14 OWF38194.1 - 0.00032 20.5 22.2 0.015 15.0 5.8 3.3 1 1 3 4 4 4 2 Laminin Domain I P4Ha_N PF08336.11 OWF38194.1 - 0.00033 20.7 14.5 1.7e+03 -1.1 14.5 4.1 1 1 0 1 1 0 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4349 PF14257.6 OWF38194.1 - 0.00037 20.0 25.4 1.1 8.6 8.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Cluap1 PF10234.9 OWF38194.1 - 0.0004 19.9 23.1 0.0078 15.6 5.4 3.0 1 1 2 3 3 3 2 Clusterin-associated protein-1 Syntaxin PF00804.25 OWF38194.1 - 0.00043 20.0 12.7 0.023 14.4 7.1 2.6 1 1 1 2 2 2 2 Syntaxin COG2 PF06148.11 OWF38194.1 - 0.00045 20.3 13.6 0.67 10.0 7.3 3.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 T3SSipB PF16535.5 OWF38194.1 - 0.00045 20.7 3.3 0.18 12.3 0.7 2.2 1 1 1 2 2 2 2 Type III cell invasion protein SipB Rho_Binding PF08912.11 OWF38194.1 - 0.00047 20.9 19.7 4.1 8.3 1.7 4.2 1 1 1 2 2 2 0 Rho Binding HMMR_N PF15905.5 OWF38194.1 - 0.00049 19.7 17.4 0.0036 16.8 17.1 1.9 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Ax_dynein_light PF10211.9 OWF38194.1 - 0.0005 20.1 16.7 0.26 11.2 2.2 3.1 1 1 2 3 3 3 2 Axonemal dynein light chain V-SNARE PF05008.15 OWF38194.1 - 0.0005 20.4 23.3 0.17 12.3 8.7 4.6 1 1 2 3 3 3 2 Vesicle transport v-SNARE protein N-terminus HSBP1 PF06825.12 OWF38194.1 - 0.0005 19.9 39.6 0.22 11.4 1.6 7.2 1 1 3 4 4 3 1 Heat shock factor binding protein 1 SOAR PF16533.5 OWF38194.1 - 0.00055 19.9 10.5 1.7 8.7 0.3 3.9 1 1 3 4 4 4 0 STIM1 Orai1-activating region Med9 PF07544.13 OWF38194.1 - 0.00057 19.9 25.0 0.49 10.5 3.2 3.6 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 FemAB PF02388.16 OWF38194.1 - 0.00062 18.8 7.6 0.13 11.1 0.4 2.2 1 1 1 2 2 2 2 FemAB family COG6 PF06419.11 OWF38194.1 - 0.00069 18.0 11.9 0.13 10.4 0.6 2.8 1 1 2 3 3 3 2 Conserved oligomeric complex COG6 CdvA PF18822.1 OWF38194.1 - 0.00071 19.4 22.7 0.22 11.3 8.9 3.4 1 1 1 2 2 2 1 CdvA-like coiled-coil domain EspB PF05802.11 OWF38194.1 - 0.00072 19.6 7.6 0.86 9.6 0.5 3.4 1 1 2 3 3 3 0 Enterobacterial EspB protein DUF4988 PF16378.5 OWF38194.1 - 0.00074 19.2 15.3 0.72 9.5 2.6 4.3 1 1 2 3 3 3 0 Domain of unknown function DMPK_coil PF08826.10 OWF38194.1 - 0.00077 19.5 29.6 0.34 11.0 4.7 4.0 1 1 3 4 4 4 1 DMPK coiled coil domain like AKNA PF12443.8 OWF38194.1 - 0.00078 20.0 15.4 3 8.6 1.6 4.6 1 1 2 3 3 3 0 AT-hook-containing transcription factor Cob_adeno_trans PF01923.18 OWF38194.1 - 0.00079 19.6 2.4 0.014 15.6 0.6 2.3 1 1 1 2 2 2 1 Cobalamin adenosyltransferase WASH_WAHD PF11945.8 OWF38194.1 - 0.00082 19.0 5.9 2.1 7.8 3.0 3.5 1 1 1 2 2 2 0 WAHD domain of WASH complex STAT_alpha PF01017.20 OWF38194.1 - 0.00085 19.3 8.4 0.056 13.3 3.5 2.6 1 1 0 2 2 2 1 STAT protein, all-alpha domain COG5 PF10392.9 OWF38194.1 - 0.00094 19.4 16.6 0.29 11.3 1.5 3.3 1 1 2 3 3 3 2 Golgi transport complex subunit 5 HAP1_N PF04849.13 OWF38194.1 - 0.0011 18.3 20.4 0.098 11.8 8.8 2.1 1 1 1 2 2 2 2 HAP1 N-terminal conserved region DUF773 PF05600.12 OWF38194.1 - 0.0011 17.8 16.5 0.02 13.6 8.0 2.1 1 1 1 2 2 2 2 CDK5 regulatory subunit-associated protein 3 HAUS-augmin3 PF14932.6 OWF38194.1 - 0.0012 18.5 18.0 0.11 12.1 9.0 2.7 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 3 DUF4446 PF14584.6 OWF38194.1 - 0.0012 18.9 9.3 1.3 9.0 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF5344 PF17279.2 OWF38194.1 - 0.0012 19.4 4.4 6 7.5 0.2 4.5 1 1 2 3 3 3 0 Family of unknown function (DUF5344) YkyA PF10368.9 OWF38194.1 - 0.0012 18.5 12.8 0.018 14.7 5.2 2.2 1 1 1 2 2 2 1 Putative cell-wall binding lipoprotein DUF2333 PF10095.9 OWF38194.1 - 0.0012 17.9 9.9 0.44 9.5 0.8 3.1 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2333) SlyX PF04102.12 OWF38194.1 - 0.0014 19.2 18.9 11 6.7 9.9 3.9 1 1 1 2 2 2 0 SlyX WEMBL PF05701.11 OWF38194.1 - 0.0014 17.4 17.1 0.002 16.9 17.1 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DASH_Dam1 PF08653.10 OWF38194.1 - 0.0014 18.3 19.8 15 5.4 4.6 5.7 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF724 PF05266.14 OWF38194.1 - 0.0016 18.3 15.2 0.016 15.0 6.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF724) Swi5 PF07061.11 OWF38194.1 - 0.0016 18.5 13.2 1.2e+03 -0.3 13.2 3.8 1 1 0 1 1 0 0 Swi5 DivIC PF04977.15 OWF38194.1 - 0.0017 18.1 21.8 0.46 10.3 2.1 3.8 1 1 3 4 4 4 1 Septum formation initiator Prominin PF05478.11 OWF38194.1 - 0.0018 16.4 17.8 0.13 10.2 1.8 2.9 1 1 2 3 3 3 2 Prominin ApoC-I PF04691.12 OWF38194.1 - 0.0018 18.1 8.2 5.9 6.9 0.1 4.9 1 1 6 7 7 7 0 Apolipoprotein C-I (ApoC-1) V-SNARE_C PF12352.8 OWF38194.1 - 0.002 18.4 16.5 2.2 8.7 0.4 5.3 1 1 4 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus Med8 PF10232.9 OWF38194.1 - 0.0021 17.7 18.4 0.8 9.2 2.2 4.1 1 1 2 4 4 4 0 Mediator of RNA polymerase II transcription complex subunit 8 Phage_GPO PF05929.11 OWF38194.1 - 0.0021 17.7 8.6 0.88 9.1 3.7 3.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MitMem_reg PF13012.6 OWF38194.1 - 0.0021 18.4 5.1 7.1 7.1 5.1 3.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Sas10_Utp3 PF04000.15 OWF38194.1 - 0.0022 18.6 21.5 1.8e+04 -6.5 21.5 4.7 1 1 0 1 1 0 0 Sas10/Utp3/C1D family bZIP_1 PF00170.21 OWF38194.1 - 0.0023 18.0 29.9 0.61 10.2 4.2 4.3 1 1 2 3 3 3 0 bZIP transcription factor Tup_N PF08581.10 OWF38194.1 - 0.0023 18.2 12.9 0.44 10.9 2.9 3.0 1 1 2 3 3 3 2 Tup N-terminal Tektin PF03148.14 OWF38194.1 - 0.0023 16.7 23.1 0.051 12.3 12.7 2.5 1 1 1 2 2 2 2 Tektin family ISG65-75 PF11727.8 OWF38194.1 - 0.0025 17.1 3.8 0.16 11.2 0.8 2.2 1 1 1 2 2 2 1 Invariant surface glycoprotein DUF5320 PF17253.2 OWF38194.1 - 0.0025 18.8 22.4 6.5 7.9 0.6 5.5 1 1 4 5 5 5 0 Family of unknown function (DUF5320) Vps51 PF08700.11 OWF38194.1 - 0.0025 17.9 8.1 11 6.2 0.2 4.5 1 1 4 5 5 5 0 Vps51/Vps67 AIP3 PF03915.13 OWF38194.1 - 0.0026 16.9 11.1 0.0034 16.5 11.1 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Golgin_A5 PF09787.9 OWF38194.1 - 0.0027 17.2 18.2 0.0058 16.1 18.2 1.5 1 1 0 1 1 1 1 Golgin subfamily A member 5 Csm1_N PF18504.1 OWF38194.1 - 0.0028 17.9 21.8 2.5 8.5 1.5 4.9 1 1 3 4 4 4 0 Csm1 N-terminal domain FUSC PF04632.12 OWF38194.1 - 0.003 16.2 6.8 0.0037 15.9 6.8 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 OWF38194.1 - 0.003 17.1 13.1 0.11 12.0 4.3 3.0 1 1 2 3 3 3 1 fzo-like conserved region DUF4140 PF13600.6 OWF38194.1 - 0.003 18.0 19.5 1.8e+04 -5.6 19.5 4.1 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) DUF1978 PF09321.10 OWF38194.1 - 0.0032 16.8 17.9 0.012 15.0 17.9 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1978) HrpB7 PF09486.10 OWF38194.1 - 0.0034 17.8 8.3 0.044 14.2 7.9 2.5 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Helo_like_N PF17111.5 OWF38194.1 - 0.0034 16.8 22.9 0.56 9.5 2.5 4.6 1 1 2 3 3 3 1 Fungal N-terminal domain of STAND proteins DUF4407 PF14362.6 OWF38194.1 - 0.0035 16.8 9.9 0.022 14.1 9.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) DLP_helical PF18709.1 OWF38194.1 - 0.0036 16.6 10.4 0.67 9.1 0.3 3.0 1 1 2 3 3 3 0 Dynamin-like helical domain V_ATPase_I PF01496.19 OWF38194.1 - 0.0036 15.3 9.1 0.82 7.5 9.1 2.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Spc19 PF08287.11 OWF38194.1 - 0.0039 17.1 29.7 0.46 10.4 17.1 3.4 1 1 1 2 2 2 1 Spc19 DUF2408 PF10303.9 OWF38194.1 - 0.0044 17.6 19.6 0.73 10.4 19.6 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) APG17 PF04108.12 OWF38194.1 - 0.0045 16.2 10.5 0.11 11.6 10.5 2.3 1 1 0 1 1 1 1 Autophagy protein Apg17 Syntaxin-6_N PF09177.11 OWF38194.1 - 0.0046 17.5 22.9 1e+04 -2.9 22.9 3.7 1 1 0 1 1 0 0 Syntaxin 6, N-terminal FTA4 PF13093.6 OWF38194.1 - 0.0048 16.8 23.0 2.7 7.9 3.4 3.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Allexi_40kDa PF05549.11 OWF38194.1 - 0.0052 16.3 10.4 0.053 13.0 4.2 2.3 1 1 1 2 2 2 2 Allexivirus 40kDa protein Sec34 PF04136.15 OWF38194.1 - 0.0062 16.4 11.7 0.7 9.8 4.3 2.9 1 1 1 2 2 2 0 Sec34-like family Lip_prot_lig_C PF10437.9 OWF38194.1 - 0.0075 16.2 8.5 30 4.7 0.1 4.2 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus ExsD PF16806.5 OWF38194.1 - 0.0079 16.1 6.6 2.9 7.7 0.6 3.5 1 1 2 3 3 3 0 Antiactivator protein ExsD Pox_RNA_Pol_19 PF05320.12 OWF38194.1 - 0.0081 16.1 4.6 4 7.4 1.0 3.2 1 1 2 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4472 PF14739.6 OWF38194.1 - 0.0088 16.8 13.2 0.12 13.1 5.8 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4472) Cortex-I_coil PF09304.10 OWF38194.1 - 0.0092 16.2 31.8 0.48 10.6 13.8 2.8 1 1 1 2 2 2 1 Cortexillin I, coiled coil Rootletin PF15035.6 OWF38194.1 - 0.0096 16.0 20.5 0.015 15.4 20.5 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CCDC144C PF14915.6 OWF38194.1 - 0.012 14.8 21.0 0.71 8.9 21.0 2.4 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Leu_zip PF15294.6 OWF38194.1 - 0.012 15.2 17.2 0.025 14.1 17.2 1.5 1 1 0 1 1 1 0 Leucine zipper Zw10 PF06248.13 OWF38194.1 - 0.013 14.1 10.6 0.19 10.2 6.7 2.1 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 Sipho_Gp157 PF05565.11 OWF38194.1 - 0.017 15.1 14.1 0.43 10.6 8.0 2.5 1 1 2 3 3 3 0 Siphovirus Gp157 Phage_HK97_TLTM PF06120.11 OWF38194.1 - 0.018 14.3 7.6 0.38 9.9 7.1 2.1 1 1 1 2 2 2 0 Tail length tape measure protein CALCOCO1 PF07888.11 OWF38194.1 - 0.019 13.8 20.7 0.026 13.4 20.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2802 PF10975.8 OWF38194.1 - 0.02 15.0 16.2 7.2 6.8 0.7 5.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2802) KfrA_N PF11740.8 OWF38194.1 - 0.02 15.5 6.7 8.5 7.1 0.2 3.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term KASH_CCD PF14662.6 OWF38194.1 - 0.021 14.7 18.1 0.066 13.0 18.1 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 OWF38194.1 - 0.021 15.1 25.1 0.12 12.6 15.9 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2959 PF11172.8 OWF38194.1 - 0.021 15.0 7.0 0.45 10.6 7.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) TelA PF05816.11 OWF38194.1 - 0.022 13.8 12.7 0.27 10.3 9.8 2.4 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) RP-C_C PF11800.8 OWF38194.1 - 0.023 14.8 10.6 1.6 8.7 0.5 3.2 1 1 3 4 4 4 0 Replication protein C C-terminal region HCMV_UL139 PF12507.8 OWF38194.1 - 0.024 15.0 15.9 0.31 11.4 0.9 3.3 1 1 2 3 3 3 0 Human Cytomegalovirus UL139 protein Cnn_1N PF07989.11 OWF38194.1 - 0.027 14.6 24.2 1.4 9.1 4.3 3.3 1 1 1 2 2 1 0 Centrosomin N-terminal motif 1 CheZ PF04344.13 OWF38194.1 - 0.028 14.4 4.0 0.3 11.0 3.7 2.2 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ Taxilin PF09728.9 OWF38194.1 - 0.028 13.6 20.8 0.036 13.3 20.8 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein TRPM_tetra PF16519.5 OWF38194.1 - 0.029 14.5 25.2 1 9.5 3.3 3.9 1 1 2 3 3 3 0 Tetramerisation domain of TRPM Phlebovirus_NSM PF07246.11 OWF38194.1 - 0.031 13.7 16.1 0.9 8.9 2.3 3.0 1 1 2 3 3 3 0 Phlebovirus nonstructural protein NS-M DUF489 PF04356.12 OWF38194.1 - 0.033 14.2 6.0 0.43 10.6 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF1298 PF06974.13 OWF38194.1 - 0.033 14.1 8.6 11 6.0 0.1 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1298) BRCA-2_OB3 PF09104.10 OWF38194.1 - 0.037 13.7 0.8 25 4.5 0.0 3.4 1 1 3 4 4 4 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF641 PF04859.12 OWF38194.1 - 0.037 14.3 16.4 1.5 9.2 4.4 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Nairo_nucleo PF02477.15 OWF38194.1 - 0.038 12.8 10.2 4.6 6.0 0.7 3.6 1 1 3 4 4 4 0 Nucleocapsid N protein DASH_Spc34 PF08657.10 OWF38194.1 - 0.042 13.6 7.2 2 8.1 2.8 2.7 1 1 1 2 2 2 0 DASH complex subunit Spc34 CAP_N PF01213.19 OWF38194.1 - 0.043 13.3 25.3 1.8e+04 -14.5 25.3 6.7 1 1 0 1 1 0 0 Adenylate cyclase associated (CAP) N terminal OmpH PF03938.14 OWF38194.1 - 0.044 14.1 4.4 1.6 9.1 4.4 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Val_tRNA-synt_C PF10458.9 OWF38194.1 - 0.045 14.0 21.8 11 6.3 0.3 5.7 1 1 5 6 6 5 0 Valyl tRNA synthetase tRNA binding arm DUF883 PF05957.13 OWF38194.1 - 0.047 14.3 17.2 16 6.2 1.4 4.1 1 1 1 2 2 1 0 Bacterial protein of unknown function (DUF883) USP8_interact PF08941.10 OWF38194.1 - 0.049 13.5 6.1 3.4 7.4 2.7 2.9 1 1 1 2 2 2 0 USP8 interacting CEP63 PF17045.5 OWF38194.1 - 0.053 13.4 20.7 0.25 11.2 20.7 1.9 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Tweety PF04906.13 OWF38194.1 - 0.059 12.0 1.0 0.65 8.6 0.2 2.0 1 1 1 2 2 2 0 Tweety PhageMin_Tail PF10145.9 OWF38194.1 - 0.059 13.2 2.6 3.5 7.4 0.5 3.1 1 1 1 2 2 2 0 Phage-related minor tail protein TMF_DNA_bd PF12329.8 OWF38194.1 - 0.061 13.3 34.1 0.17 11.9 5.2 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 OWF38194.1 - 0.066 12.9 33.2 0.82 9.3 33.2 2.2 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Filo_VP35 PF02097.15 OWF38194.1 - 0.068 12.2 1.5 16 4.4 0.1 2.9 1 1 2 3 3 3 0 Filoviridae VP35 SHE3 PF17078.5 OWF38194.1 - 0.074 12.8 28.2 0.41 10.3 18.8 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 MetOD2 PF18548.1 OWF38194.1 - 0.081 13.0 17.5 8.6 6.6 0.2 4.6 1 1 3 4 4 4 0 Metanogen output domain 2 FAP206 PF12018.8 OWF38194.1 - 0.082 12.4 7.3 0.47 9.9 2.2 2.7 1 1 0 2 2 2 0 Domain of unknown function DUF16 PF01519.16 OWF38194.1 - 0.083 13.4 11.9 0.54 10.8 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Tmemb_cc2 PF10267.9 OWF38194.1 - 0.091 11.9 18.1 1.4 8.0 6.2 2.5 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein LUC7 PF03194.15 OWF38194.1 - 0.092 12.4 9.5 2.1 8.0 4.9 2.7 1 1 1 2 2 2 0 LUC7 N_terminus GldM_N PF12081.8 OWF38194.1 - 0.099 12.7 0.4 13 5.8 0.1 2.3 1 1 1 2 2 2 0 GldM N-terminal domain Uds1 PF15456.6 OWF38194.1 - 0.1 12.8 23.1 1.9 8.7 13.6 2.7 1 1 1 2 2 2 0 Up-regulated During Septation FmiP_Thoc5 PF09766.9 OWF38194.1 - 0.12 11.6 21.3 3.3 6.9 2.3 2.9 1 1 2 3 3 3 0 Fms-interacting protein/Thoc5 YojJ PF10372.9 OWF38194.1 - 0.12 12.4 12.6 13 6.0 0.6 4.6 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF4559 PF15112.6 OWF38194.1 - 0.13 11.9 15.8 15 5.1 15.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) IDO PF01231.18 OWF38194.1 - 0.13 11.0 7.4 4.1 6.1 0.3 3.2 1 1 2 3 3 3 0 Indoleamine 2,3-dioxygenase DUF1759 PF03564.15 OWF38194.1 - 0.13 12.2 4.0 0.14 12.1 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) NPA PF16469.5 OWF38194.1 - 0.13 12.8 8.2 24 5.5 0.4 3.9 1 1 2 3 3 3 0 Nematode polyprotein allergen ABA-1 DUF4763 PF15960.5 OWF38194.1 - 0.13 11.5 21.1 0.77 9.0 2.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) MT PF12777.7 OWF38194.1 - 0.13 11.2 3.5 11 5.0 0.2 2.9 1 1 2 3 3 3 0 Microtubule-binding stalk of dynein motor PCRF PF03462.18 OWF38194.1 - 0.14 12.0 11.4 0.65 9.8 4.0 2.2 1 1 1 2 2 2 0 PCRF domain PI_PP_I PF18363.1 OWF38194.1 - 0.15 12.3 2.3 39 4.5 0.0 3.0 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain FIN1 PF17300.2 OWF38194.1 - 0.15 11.6 19.6 1.7 8.0 3.9 3.0 1 1 2 3 3 3 0 Filaments in between nuclei protein-1 PI3K_P85_iSH2 PF16454.5 OWF38194.1 - 0.15 11.6 23.5 2.7 7.6 3.9 3.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Hemagglutinin PF00509.18 OWF38194.1 - 0.15 10.4 10.5 2.3 6.5 0.5 2.9 1 1 2 3 3 3 0 Haemagglutinin Yuri_gagarin PF15934.5 OWF38194.1 - 0.16 11.8 17.9 0.81 9.5 17.9 1.9 1 1 0 1 1 1 0 Yuri gagarin DUF2779 PF11074.8 OWF38194.1 - 0.17 12.4 9.4 22 5.5 0.7 4.0 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) Phasin PF05597.11 OWF38194.1 - 0.18 11.8 15.1 95 3.0 0.2 3.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BRCC36_C PF18110.1 OWF38194.1 - 0.24 11.6 13.0 36 4.6 0.9 5.1 1 1 4 5 5 4 0 BRCC36 C-terminal helical domain DUF2205 PF10224.9 OWF38194.1 - 0.24 11.4 23.3 1.3 9.1 3.5 4.2 1 1 3 4 4 4 0 Short coiled-coil protein YPEB PF14620.6 OWF38194.1 - 0.25 10.7 10.4 2.8 7.2 0.7 2.7 1 1 1 2 2 2 0 YpeB sporulation Csm2_III-A PF03750.13 OWF38194.1 - 0.25 12.2 4.5 1.9 9.4 0.3 2.2 1 1 1 2 2 2 0 Csm2 Type III-A Baculo_F PF12259.8 OWF38194.1 - 0.25 9.8 4.5 0.63 8.5 0.6 2.1 1 1 1 2 2 2 0 Baculovirus F protein DASH_Dad2 PF08654.10 OWF38194.1 - 0.28 11.6 11.7 12 6.4 1.2 3.8 1 1 2 3 3 3 0 DASH complex subunit Dad2 PEARLI-4 PF05278.12 OWF38194.1 - 0.28 10.7 15.5 1.6 8.2 0.3 2.8 1 1 2 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) LOH1CR12 PF10158.9 OWF38194.1 - 0.3 11.1 8.7 2.9 7.9 0.4 2.9 1 1 2 3 3 3 0 Tumour suppressor protein DUF3847 PF12958.7 OWF38194.1 - 0.3 11.2 19.7 4.2 7.5 1.4 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3847) DUF2913 PF11140.8 OWF38194.1 - 0.31 10.8 8.3 5.5 6.7 0.3 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2913) MCU PF04678.13 OWF38194.1 - 0.32 11.1 8.6 1.6e+02 2.3 8.6 3.0 1 1 0 1 1 1 0 Mitochondrial calcium uniporter CorA PF01544.18 OWF38194.1 - 0.36 10.1 19.9 8.7 5.6 19.9 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PIEZO PF15917.5 OWF38194.1 - 0.36 10.3 7.8 14 5.1 4.4 3.2 1 1 1 2 2 2 0 Piezo Dzip-like_N PF13815.6 OWF38194.1 - 0.36 10.8 12.8 5.9 6.9 0.5 3.3 1 1 2 3 3 3 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Arm-DNA-bind_5 PF17293.2 OWF38194.1 - 0.39 11.2 12.2 1.3 9.5 0.7 3.4 1 1 1 2 2 2 0 Arm DNA-binding domain MtrG PF04210.13 OWF38194.1 - 0.39 10.6 10.6 57 3.7 0.0 5.2 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G RasGAP_C PF03836.15 OWF38194.1 - 0.41 10.8 13.4 22 5.2 1.6 3.0 1 1 1 2 2 2 0 RasGAP C-terminus zf-ZPR1 PF03367.13 OWF38194.1 - 0.44 10.4 7.2 15 5.4 7.2 2.5 1 1 0 1 1 1 0 ZPR1 zinc-finger domain DUF4404 PF14357.6 OWF38194.1 - 0.44 11.2 33.7 5.7 7.7 5.0 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) INCA1 PF15142.6 OWF38194.1 - 0.48 10.4 3.2 5.5 7.0 0.2 2.8 1 1 2 3 3 2 0 INCA1 TSNAXIP1_N PF15739.5 OWF38194.1 - 0.52 10.7 11.8 3.4 8.1 9.2 2.2 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus LPP PF04728.13 OWF38194.1 - 0.52 10.7 10.9 11 6.5 0.9 3.9 1 1 1 3 3 3 0 Lipoprotein leucine-zipper Tho2 PF11262.8 OWF38194.1 - 0.57 9.3 11.5 0.55 9.4 4.5 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 NEMO PF11577.8 OWF38194.1 - 0.57 10.2 25.0 1.7 8.7 5.9 4.3 1 1 3 4 4 4 0 NF-kappa-B essential modulator NEMO FlxA PF14282.6 OWF38194.1 - 0.58 10.2 8.1 2.9 7.9 1.0 3.0 1 1 1 3 3 3 0 FlxA-like protein Syntaphilin PF15290.6 OWF38194.1 - 0.59 9.7 29.3 6.7 6.3 10.2 4.2 1 1 3 4 4 4 0 Golgi-localised syntaxin-1-binding clamp KAR9 PF08580.10 OWF38194.1 - 0.65 8.5 12.2 0.4 9.2 4.5 1.9 1 1 1 2 2 2 0 Yeast cortical protein KAR9 zf-CpG_bind_C PF12269.8 OWF38194.1 - 0.65 9.7 11.6 13 5.5 1.0 3.2 1 1 3 4 4 4 0 CpG binding protein zinc finger C terminal domain Hormone_1 PF00103.20 OWF38194.1 - 0.68 9.6 8.6 4.1 7.1 0.9 2.8 1 1 2 3 3 3 0 Somatotropin hormone family DUF5101 PF17031.5 OWF38194.1 - 0.68 10.1 14.2 5.3 7.2 0.6 3.3 1 1 0 3 3 3 0 Domain of unknown function (DUF5101) DUF4527 PF15030.6 OWF38194.1 - 0.71 9.3 19.1 0.68 9.3 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) Lectin_N PF03954.14 OWF38194.1 - 0.75 9.6 12.6 8.6 6.1 0.8 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain SH3BP5 PF05276.14 OWF38194.1 - 0.89 9.3 11.0 23 4.7 1.6 3.3 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Noelin-1 PF12308.8 OWF38194.1 - 0.93 9.5 12.5 1.2e+03 -0.4 12.5 3.0 1 1 0 1 1 0 0 Neurogenesis glycoprotein UPF0449 PF15136.6 OWF38194.1 - 1.1 9.8 22.8 1.2e+03 0.0 11.7 4.8 1 1 1 2 2 0 0 Uncharacterised protein family UPF0449 Synaptonemal_3 PF15191.6 OWF38194.1 - 1.1 9.1 15.4 3.7 7.4 1.0 4.0 1 1 3 4 4 4 0 Synaptonemal complex central element protein 3 Med30 PF11315.8 OWF38194.1 - 1.1 9.5 9.9 6.6 6.9 5.7 2.3 1 1 1 2 2 2 0 Mediator complex subunit 30 DegS PF05384.11 OWF38194.1 - 1.1 8.7 18.8 9 5.8 10.9 2.8 1 1 0 1 1 1 0 Sensor protein DegS AAA_23 PF13476.6 OWF38194.1 - 1.2 9.6 27.4 1.8e+04 -4.5 27.4 2.9 1 1 0 1 1 0 0 AAA domain CCDC-167 PF15188.6 OWF38194.1 - 1.2 9.6 29.7 2.6 8.5 7.3 3.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 CAMSAP_CC1 PF17095.5 OWF38194.1 - 1.3 8.9 30.5 9.4 6.2 2.5 4.7 1 1 4 5 5 5 0 Spectrin-binding region of Ca2+-Calmodulin DUF1043 PF06295.12 OWF38194.1 - 1.4 9.0 11.0 5.7e+02 0.5 11.0 3.1 1 1 0 1 1 0 0 Protein of unknown function (DUF1043) Zwint PF15556.6 OWF38194.1 - 1.5 8.3 13.5 4.5 6.7 5.5 2.4 1 1 1 2 2 2 0 ZW10 interactor MtrB PF05440.12 OWF38194.1 - 1.5 9.3 4.2 35 4.9 0.1 3.2 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B LMBR1 PF04791.16 OWF38194.1 - 1.6 7.6 13.0 12 4.7 13.0 2.3 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF3782 PF12644.7 OWF38194.1 - 1.6 9.0 8.9 3e+03 -1.5 8.9 3.6 1 1 0 1 1 0 0 Protein of unknown function (DUF3782) Baculo_gp64 PF03273.13 OWF38194.1 - 1.9 7.2 10.6 3.6 6.3 0.5 2.9 1 1 2 3 3 3 0 Baculovirus gp64 envelope glycoprotein family MutS_IV PF05190.18 OWF38194.1 - 2 8.8 26.7 8 6.9 3.2 4.7 1 1 4 5 5 5 0 MutS family domain IV Peptidase_S66 PF02016.15 OWF38194.1 - 2.2 8.4 4.4 1.4e+02 2.6 4.4 2.8 1 1 0 1 1 1 0 LD-carboxypeptidase N-terminal domain Goodbye PF17109.5 OWF38194.1 - 2.3 8.7 7.8 15 6.1 0.2 3.3 1 1 3 4 4 4 0 fungal STAND N-terminal Goodbye domain DUF1241 PF06840.11 OWF38194.1 - 2.4 7.8 10.1 1 9.0 4.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) AATF-Che1 PF13339.6 OWF38194.1 - 2.7 8.7 13.8 1.1e+03 0.2 13.8 2.8 1 1 0 1 1 0 0 Apoptosis antagonizing transcription factor DASH_Dad1 PF08649.10 OWF38194.1 - 3 8.1 8.5 14 6.0 0.5 3.8 1 1 2 4 4 3 0 DASH complex subunit Dad1 DUF2968 PF11180.8 OWF38194.1 - 3 7.4 9.6 3.1 7.4 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF5623 PF18536.1 OWF38194.1 - 3.1 8.1 17.8 1.8e+04 -9.5 17.8 5.9 1 1 0 1 1 0 0 Domain of unknown function (DUF5623) DUF4600 PF15372.6 OWF38194.1 - 3.2 8.2 19.5 12 6.4 10.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Casc1_N PF15927.5 OWF38194.1 - 3.3 7.4 16.1 14 5.3 0.8 3.2 1 1 2 3 3 3 0 Cancer susceptibility candidate 1 N-terminus JIP_LZII PF16471.5 OWF38194.1 - 3.9 7.7 28.9 2.7 8.2 4.5 3.6 1 1 1 2 2 1 0 JNK-interacting protein leucine zipper II Sugarporin_N PF11471.8 OWF38194.1 - 4 7.5 25.4 5.4 7.1 1.1 5.4 1 1 5 7 7 6 0 Maltoporin periplasmic N-terminal extension IL2 PF00715.17 OWF38194.1 - 4.1 7.3 11.0 1.6e+02 2.1 10.7 2.4 1 1 0 1 1 1 0 Interleukin 2 DUF848 PF05852.11 OWF38194.1 - 4.7 7.3 17.6 3.8 7.6 5.3 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) MPS2 PF17060.5 OWF38194.1 - 5.5 6.1 27.1 3.3 6.9 6.3 2.9 1 1 2 3 3 3 0 Monopolar spindle protein 2 MIF4G_like_2 PF09090.11 OWF38194.1 - 5.6 6.3 11.6 1.5e+02 1.7 11.6 2.2 1 1 0 1 1 1 0 MIF4G like zf-C4H2 PF10146.9 OWF38194.1 - 6.1 7.1 13.6 51 4.1 13.2 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein CHDCT2 PF08074.11 OWF38194.1 - 6.1 7.0 15.7 45 4.2 0.8 3.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF2381 PF09544.10 OWF38194.1 - 6.6 6.2 10.7 22 4.5 0.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2381) DUF2721 PF11026.8 OWF38194.1 - 6.7 6.6 16.7 8.8 6.2 1.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) Fungal_trans_2 PF11951.8 OWF38194.1 - 7.2 5.3 14.2 4.2 6.1 2.0 2.9 1 1 2 3 3 3 0 Fungal specific transcription factor domain DUF87 PF01935.17 OWF38194.1 - 7.3 6.6 12.3 3.2e+02 1.2 12.3 2.3 1 1 0 1 1 1 0 Helicase HerA, central domain 5_nucleotid PF05761.14 OWF38194.1 - 7.4 5.4 9.3 9 5.1 3.1 2.2 1 1 1 2 2 2 0 5' nucleotidase family ZapA PF05164.13 OWF38194.1 - 9.9 6.7 21.1 1.8e+04 -10.7 21.1 4.2 1 1 0 1 1 0 0 Cell division protein ZapA bVLRF1 PF18826.1 OWF38196.1 - 2.7e-56 189.6 0.0 6.1e-56 188.4 0.0 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 OWF38196.1 - 5.7e-13 48.5 2.0 5.7e-13 48.5 2.0 1.9 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank PF00023.30 OWF38196.1 - 6.8e-06 26.3 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 OWF38196.1 - 1.9e-05 25.1 0.0 6.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF38196.1 - 2.7e-05 24.7 0.0 0.0012 19.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF38196.1 - 0.00018 21.8 0.0 0.0041 17.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF38196.1 - 0.0014 18.9 0.0 0.039 14.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Aldo_ket_red PF00248.21 OWF38197.1 - 1.8e-63 214.5 0.0 2.1e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATG27 PF09451.10 OWF38198.1 - 8.5e-14 52.0 0.0 1.2e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF38198.1 - 1.4e-11 44.0 0.0 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 OWF38198.1 - 1.1e-07 32.0 0.2 0.00051 20.1 0.1 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Actin PF00022.19 OWF38199.1 - 2.3e-67 227.4 0.0 3.7e-63 213.5 0.0 2.8 1 1 0 1 1 1 1 Actin ATG27 PF09451.10 OWF38200.1 - 8.7e-17 61.8 0.2 1.1e-16 61.5 0.2 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF38200.1 - 5.7e-14 51.8 0.0 6.5e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 OWF38200.1 - 0.0001 22.4 0.8 0.02 15.0 0.5 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat FANCA_interact PF15751.5 OWF38200.1 - 0.032 14.7 0.0 0.058 13.9 0.0 1.3 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain DUF1408 PF07193.11 OWF38200.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) ATG27 PF09451.10 OWF38201.1 - 8.8e-12 45.4 0.7 2.7e-11 43.8 0.7 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF38201.1 - 1.8e-06 27.2 1.2 2.1e-06 27.0 0.7 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 OWF38201.1 - 0.00048 20.2 1.0 0.018 15.1 0.8 2.3 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Spore_YhaL PF14147.6 OWF38201.1 - 1.2 8.9 6.3 1.7 8.4 2.8 2.4 2 1 0 2 2 2 0 Sporulation protein YhaL ATG27 PF09451.10 OWF38202.1 - 2.8e-05 24.1 0.0 3.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OWF38202.1 - 4.5e-05 23.5 0.1 0.066 13.3 0.0 2.1 1 1 1 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRIMA1 PF16101.5 OWF38202.1 - 0.62 10.1 3.3 1.1 9.3 3.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CIMR PF00878.18 OWF38203.1 - 0.00026 21.1 1.8 0.023 14.8 0.8 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Smim3 PF17307.2 OWF38203.1 - 0.027 14.0 1.2 0.055 13.0 1.2 1.6 1 0 0 1 1 1 0 Small integral membrane protein 3 cNMP_binding PF00027.29 OWF38204.1 - 1.3e-15 57.2 0.2 0.00071 19.6 0.0 5.1 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain UBX PF00789.20 OWF38206.1 - 1.7e-15 57.0 0.0 3.2e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain LRR_4 PF12799.7 OWF38206.1 - 2.3e-14 53.3 38.2 0.00052 20.3 0.5 8.6 6 2 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF38206.1 - 1.4e-11 44.0 22.3 6.4e-06 25.8 0.3 6.0 6 1 1 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 OWF38206.1 - 4.3e-06 26.4 39.3 0.0079 16.2 0.0 12.9 13 1 0 13 13 13 2 Leucine Rich repeat UBA PF00627.31 OWF38206.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Arc_trans_TRASH PF08394.10 OWF38206.1 - 0.12 12.7 0.8 25 5.3 0.1 2.5 2 0 0 2 2 2 0 Archaeal TRASH domain UBZ_FAAP20 PF15750.5 OWF38206.1 - 0.25 11.3 7.3 5.6 7.0 0.3 3.3 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger RRM_1 PF00076.22 OWF38207.1 - 3.9e-17 61.8 0.0 5.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 OWF38207.1 - 2 7.2 13.3 3.4 6.4 13.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain MFS_1 PF07690.16 OWF38208.1 - 1e-14 54.3 41.9 9.4e-10 37.9 19.4 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 OWF38209.1 - 5.1e-11 42.1 51.9 2.2e-08 33.4 43.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OWF38210.1 - 0.00083 18.4 24.4 0.013 14.4 24.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF38211.1 - 0.0017 17.3 15.6 0.0022 17.0 15.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF38212.1 - 3.1e-12 46.1 52.1 3.5e-12 45.9 48.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Xan_ur_permease PF00860.20 OWF38213.1 - 5.9e-62 209.6 21.1 7.7e-62 209.2 21.1 1.1 1 0 0 1 1 1 1 Permease family Death PF00531.22 OWF38214.1 - 0.00028 21.0 0.0 0.0005 20.2 0.0 1.4 1 0 0 1 1 1 1 Death domain Fibrinogen_C PF00147.18 OWF38216.1 - 2.7e-20 73.1 2.1 3e-20 73.0 2.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF38217.1 - 2.7e-62 210.5 1.6 3.7e-62 210.0 1.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Peptidase_M49 PF03571.15 OWF38218.1 - 2.4e-230 765.6 0.0 3.3e-230 765.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 Homeodomain PF00046.29 OWF38219.1 - 2.7e-17 62.4 0.6 4.3e-17 61.7 0.6 1.3 1 0 0 1 1 1 1 Homeodomain zf-C2H2_6 PF13912.6 OWF38220.1 - 2.4e-06 27.4 10.9 18 5.5 0.1 9.2 9 0 0 9 9 9 2 C2H2-type zinc finger DUF5525 PF17663.1 OWF38220.1 - 0.074 11.1 19.0 2.6 6.0 1.9 5.0 1 1 4 5 5 5 0 Family of unknown function (DUF5525) F-box-like PF12937.7 OWF38221.1 - 2.4e-15 56.1 0.8 6.4e-15 54.8 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF38221.1 - 4.7e-09 35.9 0.8 4.7e-09 35.9 0.8 1.8 2 0 0 2 2 2 1 F-box domain VCBS PF13517.6 OWF38222.1 - 1e-12 48.4 7.7 0.002 18.7 0.2 6.0 4 3 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 OWF38222.1 - 2e-06 27.5 1.8 0.0078 16.1 0.5 4.6 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_2 PF13360.6 OWF38222.1 - 2.3e-06 27.4 0.1 6.6e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 OWF38222.1 - 2.9e-05 24.4 4.1 0.12 12.9 0.1 4.6 4 0 0 4 4 4 2 PQQ-like domain FG-GAP PF01839.23 OWF38222.1 - 0.0067 16.5 12.1 21 5.3 0.5 5.5 5 0 0 5 5 5 2 FG-GAP repeat PALP PF00291.25 OWF38223.1 - 2e-71 240.8 0.2 2.3e-71 240.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CbbQ_C PF08406.10 OWF38223.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal Aminotran_1_2 PF00155.21 OWF38223.1 - 0.17 11.0 0.0 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II LPMO_10 PF03067.15 OWF38224.1 - 1.8e-21 77.7 0.1 2.4e-21 77.3 0.1 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading RAB3GAP2_C PF14656.6 OWF38225.1 - 3.4e-158 527.6 8.1 5.3e-158 527.0 8.1 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 OWF38225.1 - 1.4e-144 482.4 0.0 2.9e-144 481.4 0.0 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ArAE_1_C PF11728.8 OWF38225.1 - 0.26 11.3 5.3 0.14 12.1 2.7 1.9 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain Rad51 PF08423.11 OWF38226.1 - 1.5e-50 171.9 0.0 2e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OWF38226.1 - 1.5e-06 27.9 0.1 0.0016 18.0 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 OWF38226.1 - 6.6e-06 25.6 0.1 0.0002 20.8 0.1 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 OWF38226.1 - 7.2e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OWF38226.1 - 1.7e-05 24.3 0.8 0.00012 21.6 0.8 2.1 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 OWF38226.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tex_N PF09371.10 OWF38227.1 - 1.4e-45 155.2 0.3 3.8e-45 153.8 0.0 1.9 2 0 0 2 2 2 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 OWF38227.1 - 1.4e-43 148.4 0.1 4.1e-43 146.8 0.1 1.9 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 OWF38227.1 - 5.4e-23 81.0 0.0 1.5e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 OWF38227.1 - 3e-14 53.6 0.1 2.8e-13 50.6 0.0 2.7 2 0 0 2 2 2 1 HHH domain S1 PF00575.23 OWF38227.1 - 1.9e-10 40.9 0.4 4.9e-10 39.6 0.4 1.8 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 OWF38227.1 - 2.2e-07 30.8 0.1 1.1e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 OWF38227.1 - 7e-05 23.1 0.0 0.00028 21.2 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1_2 PF13509.6 OWF38227.1 - 0.00067 19.7 0.4 0.0016 18.5 0.4 1.6 1 0 0 1 1 1 1 S1 domain KdgM PF06178.13 OWF38227.1 - 0.06 13.0 0.1 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) HTH_6 PF01418.17 OWF38227.1 - 0.09 12.8 0.5 8.4 6.5 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain, rpiR family DUF922 PF06037.11 OWF38227.1 - 0.86 9.4 3.4 0.42 10.4 0.2 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF922) 7tm_1 PF00001.21 OWF38228.1 - 3e-17 62.8 24.0 5e-17 62.1 24.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF38228.1 - 0.00013 21.4 26.5 0.00029 20.3 26.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF38228.1 - 0.0018 17.9 24.7 0.016 14.8 24.7 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CENP-F_leu_zip PF10473.9 OWF38229.1 - 0.0095 16.0 32.8 0.0095 16.0 32.8 7.4 2 2 5 7 7 7 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 OWF38229.1 - 0.083 10.4 85.4 0.019 12.5 55.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 OWF38229.1 - 0.69 10.1 118.4 0.025 14.8 13.5 6.2 3 2 3 6 6 6 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OWF38229.1 - 1.4 9.4 108.9 0.084 13.3 31.9 5.2 1 1 4 5 5 5 0 Fez1 Spc7 PF08317.11 OWF38229.1 - 3.2 6.5 105.9 0.053 12.4 33.9 4.4 2 1 2 4 4 4 0 Spc7 kinetochore protein WXG100 PF06013.12 OWF38229.1 - 5.6 7.3 28.9 0.95 9.7 1.2 6.0 6 1 0 6 6 6 0 Proteins of 100 residues with WXG Isochorismatase PF00857.20 OWF38230.1 - 0.055 13.7 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Isochorismatase family Mce4_CUP1 PF11887.8 OWF38230.1 - 0.22 11.0 1.7 0.46 9.9 1.7 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative CALCOCO1 PF07888.11 OWF38230.1 - 0.27 10.1 45.8 1.1 8.0 26.0 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc29 PF17082.5 OWF38230.1 - 1.6 8.6 39.2 0.064 13.1 3.7 4.1 1 1 1 3 3 3 0 Spindle Pole Component 29 DASH_Dam1 PF08653.10 OWF38230.1 - 4.1 7.3 5.5 14 5.5 0.0 4.4 4 1 2 6 6 6 0 DASH complex subunit Dam1 ATG16 PF08614.11 OWF38230.1 - 4.1 7.6 54.7 5.4 7.2 11.6 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF4618 PF15397.6 OWF38230.1 - 6.4 6.1 49.6 2 7.8 9.5 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 OWF38230.1 - 7.1 7.0 38.6 4.3 7.7 2.2 5.8 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TLD PF07534.16 OWF38231.1 - 4.3e-11 43.2 0.0 6.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 TLD MMR_HSR1 PF01926.23 OWF38231.1 - 3e-05 24.0 0.0 9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF38231.1 - 0.00015 21.7 0.1 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 OWF38231.1 - 0.00058 19.5 0.7 0.07 12.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OWF38231.1 - 0.0006 19.2 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 OWF38231.1 - 0.001 18.7 0.1 0.095 12.2 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF38231.1 - 0.0031 16.9 0.1 0.64 9.3 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MCM PF00493.23 OWF38231.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 OWF38231.1 - 0.011 15.4 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OWF38231.1 - 0.024 14.4 0.7 7.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.21 OWF38231.1 - 0.03 13.8 0.1 0.54 9.7 0.2 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 OWF38231.1 - 0.039 14.3 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 OWF38231.1 - 0.12 12.4 0.4 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 OWF38231.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 OWF38231.1 - 0.14 11.2 0.0 0.3 10.2 0.0 1.6 1 1 0 1 1 1 0 G-protein alpha subunit AIG1 PF04548.16 OWF38231.1 - 0.16 11.3 0.3 0.5 9.7 0.1 1.9 2 0 0 2 2 2 0 AIG1 family APG6_N PF17675.1 OWF38232.1 - 2.8e-06 27.9 66.9 0.0011 19.5 7.3 6.0 2 1 4 7 7 6 4 Apg6 coiled-coil region Spc7 PF08317.11 OWF38232.1 - 3.4e-06 26.2 63.1 0.00024 20.1 12.6 3.7 1 1 2 3 3 3 2 Spc7 kinetochore protein DUF3450 PF11932.8 OWF38232.1 - 3.3e-05 23.3 58.4 8.2e-05 22.0 6.7 5.5 2 1 4 6 6 6 3 Protein of unknown function (DUF3450) ATG16 PF08614.11 OWF38232.1 - 9.6e-05 22.7 60.2 0.0017 18.6 9.5 3.8 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) HsbA PF12296.8 OWF38232.1 - 0.00025 21.4 16.8 0.022 15.2 0.9 5.1 3 1 1 5 5 4 1 Hydrophobic surface binding protein A BRE1 PF08647.11 OWF38232.1 - 0.0011 18.9 4.7 0.0011 18.9 4.7 5.9 1 1 5 6 6 6 2 BRE1 E3 ubiquitin ligase WEMBL PF05701.11 OWF38232.1 - 0.0012 17.7 47.9 0.0042 15.8 42.5 2.4 1 1 2 3 3 3 1 Weak chloroplast movement under blue light TMF_TATA_bd PF12325.8 OWF38232.1 - 0.0017 18.6 62.9 0.0081 16.4 17.2 5.6 2 1 5 7 7 6 2 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 OWF38232.1 - 0.0018 18.3 69.8 0.047 13.7 10.8 5.2 2 1 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 OWF38232.1 - 0.0018 18.9 62.3 0.46 11.1 3.7 5.5 1 1 4 5 5 5 3 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 OWF38232.1 - 0.0033 17.6 70.5 0.076 13.1 10.4 4.6 2 1 3 5 5 4 3 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 OWF38232.1 - 0.0039 17.4 62.2 0.02 15.1 19.6 4.1 1 1 2 4 4 4 2 JNK_SAPK-associated protein-1 HMMR_N PF15905.5 OWF38232.1 - 0.0042 16.6 12.0 0.0042 16.6 12.0 3.3 1 1 2 3 3 3 1 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 OWF38232.1 - 0.0055 16.6 8.0 0.0055 16.6 8.0 3.8 1 1 3 4 4 3 2 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 OWF38232.1 - 0.0068 16.5 57.1 0.72 9.9 19.7 4.7 2 1 2 5 5 4 3 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 OWF38232.1 - 0.0074 16.3 1.8 0.0074 16.3 1.8 5.8 2 1 3 5 5 5 2 Protein of unknown function (DUF1664) DUF641 PF04859.12 OWF38232.1 - 0.0089 16.4 4.3 0.0089 16.4 4.3 5.0 2 1 3 5 5 5 1 Plant protein of unknown function (DUF641) SSI PF00720.17 OWF38232.1 - 0.012 15.5 0.1 0.82 9.7 0.0 2.9 2 1 0 2 2 2 0 Subtilisin inhibitor-like TMF_DNA_bd PF12329.8 OWF38232.1 - 0.012 15.5 3.7 0.012 15.5 3.7 6.5 5 2 1 7 7 6 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 OWF38232.1 - 0.014 14.7 68.9 0.047 13.0 3.1 5.4 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding Cep57_MT_bd PF06657.13 OWF38232.1 - 0.017 15.6 41.5 0.12 12.9 1.3 6.7 3 2 2 6 6 5 0 Centrosome microtubule-binding domain of Cep57 Fez1 PF06818.15 OWF38232.1 - 0.023 15.1 59.4 0.061 13.8 8.9 3.6 1 1 3 4 4 4 0 Fez1 AAA_13 PF13166.6 OWF38232.1 - 0.032 12.9 48.1 0.52 8.9 23.0 2.6 1 1 1 2 2 2 0 AAA domain HOOK PF05622.12 OWF38232.1 - 0.037 12.2 61.8 0.039 12.1 34.6 2.3 1 1 1 2 2 2 0 HOOK protein bZIP_1 PF00170.21 OWF38232.1 - 0.052 13.6 0.2 0.052 13.6 0.2 7.2 7 1 1 8 8 7 0 bZIP transcription factor KASH_CCD PF14662.6 OWF38232.1 - 0.083 12.7 64.4 0.0094 15.8 31.8 4.0 1 1 2 3 3 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 OWF38232.1 - 0.091 12.8 62.9 0.69 10.0 9.9 6.3 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 OWF38232.1 - 0.12 10.7 62.2 3.7 5.8 62.2 2.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Rootletin PF15035.6 OWF38232.1 - 0.13 12.3 53.5 4.1 7.4 23.1 4.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.6 OWF38232.1 - 0.13 11.5 42.8 0.079 12.3 15.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 OWF38232.1 - 0.16 12.1 46.2 0.085 13.0 2.2 6.3 1 1 6 7 7 7 0 Centrosome localisation domain of PPC89 DUF3800 PF12686.7 OWF38232.1 - 0.26 11.9 2.7 36 5.0 2.6 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF3584 PF12128.8 OWF38232.1 - 0.4 8.1 54.3 0.12 9.9 42.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TACC_C PF05010.14 OWF38232.1 - 0.69 9.7 55.1 0.54 10.0 15.4 3.8 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TolA_bind_tri PF16331.5 OWF38232.1 - 0.9 9.7 59.9 0.17 12.0 4.6 7.1 1 1 4 6 6 6 0 TolA binding protein trimerisation OmpH PF03938.14 OWF38232.1 - 1.1 9.5 62.5 1.1 9.5 5.0 4.6 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 OWF38232.1 - 1.2 9.5 49.0 0.45 10.9 6.8 6.4 2 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 OWF38232.1 - 1.4 9.2 51.8 3.9 7.8 13.4 5.1 2 1 2 4 4 3 0 Domain of unknown function (DUF5082) DUF2353 PF09789.9 OWF38232.1 - 1.9 7.8 56.3 1.1 8.5 19.4 2.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF4201 PF13870.6 OWF38232.1 - 2 8.1 57.8 5.6 6.7 7.5 4.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) Lebercilin PF15619.6 OWF38232.1 - 2 8.0 65.8 0.72 9.5 20.2 4.5 1 1 3 4 4 3 0 Ciliary protein causing Leber congenital amaurosis disease Bacillus_HBL PF05791.11 OWF38232.1 - 3.2 7.5 44.8 0.99 9.2 3.6 4.7 2 1 2 5 5 4 0 Bacillus haemolytic enterotoxin (HBL) COG5 PF10392.9 OWF38232.1 - 3.8 7.7 35.8 0.27 11.4 1.0 5.5 2 1 4 6 6 5 0 Golgi transport complex subunit 5 Atg14 PF10186.9 OWF38232.1 - 3.9 6.5 53.6 1.6 7.7 9.4 3.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPK_catalytic PF04263.16 OWF38232.1 - 4.3 7.4 20.5 12 6.0 0.9 4.4 1 1 1 4 4 4 0 Thiamin pyrophosphokinase, catalytic domain zf-C4H2 PF10146.9 OWF38232.1 - 4.5 7.5 47.1 1.5 9.1 8.6 3.7 1 1 2 3 3 3 0 Zinc finger-containing protein DUF4200 PF13863.6 OWF38232.1 - 5.1 7.5 64.9 0.55 10.6 7.0 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4200) DUF812 PF05667.11 OWF38232.1 - 5.1 5.8 62.1 14 4.4 17.3 3.6 1 1 1 2 2 1 0 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 OWF38232.1 - 8.2 5.9 53.8 1.7 8.2 16.1 3.9 1 1 3 4 4 4 0 HAUS augmin-like complex subunit 3 DUF3584 PF12128.8 OWF38233.1 - 0.0013 16.4 35.0 0.0019 15.9 35.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PRKG1_interact PF15898.5 OWF38233.1 - 0.024 15.5 11.0 0.024 15.5 11.0 5.2 1 1 6 7 7 7 0 cGMP-dependent protein kinase interacting domain NHase_beta PF02211.15 OWF38233.1 - 0.024 14.7 1.5 0.052 13.6 1.5 1.5 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Golgin_A5 PF09787.9 OWF38233.1 - 2.4 7.5 56.4 0.39 10.1 18.8 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 Sec34 PF04136.15 OWF38233.1 - 7.9 6.3 25.1 0.059 13.3 7.1 3.6 3 1 0 3 3 3 0 Sec34-like family Cep57_CLD_2 PF14197.6 OWF38234.1 - 3.1e-05 24.0 2.5 3.1e-05 24.0 2.5 5.9 5 2 1 6 6 6 1 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 OWF38234.1 - 0.0024 17.7 6.1 0.0024 17.7 6.1 5.4 3 1 1 5 5 5 3 Coiled-coil region of CCDC155 or KASH Yippee-Mis18 PF03226.14 OWF38234.1 - 0.13 12.5 1.0 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly APG6_N PF17675.1 OWF38234.1 - 0.22 12.0 68.9 0.028 14.9 8.8 5.7 3 2 2 5 5 5 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 OWF38234.1 - 0.88 9.8 56.3 1.4 9.1 3.2 6.1 2 2 4 6 6 6 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.6 OWF38234.1 - 2.6 8.0 61.6 0.062 13.3 1.7 4.4 2 1 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.8 OWF38235.1 - 3.8e-05 23.6 2.8 3.8e-05 23.6 2.8 5.5 3 2 2 5 5 5 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 OWF38235.1 - 0.0045 15.9 6.8 0.0045 15.9 6.8 3.1 2 1 0 3 3 3 1 Spc7 kinetochore protein Leu_zip PF15294.6 OWF38235.1 - 0.0053 16.3 14.1 0.0053 16.3 14.1 2.3 1 1 1 2 2 2 1 Leucine zipper ADIP PF11559.8 OWF38235.1 - 0.006 16.7 36.8 0.12 12.5 0.8 4.5 2 1 3 5 5 5 3 Afadin- and alpha -actinin-Binding Mto2_bdg PF12808.7 OWF38235.1 - 0.0062 16.8 1.7 0.0062 16.8 1.7 2.7 3 0 0 3 3 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region FlaC_arch PF05377.11 OWF38235.1 - 0.012 16.0 18.0 0.18 12.2 0.2 4.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Glu-tRNAGln PF02686.15 OWF38235.1 - 0.014 15.6 1.5 0.48 10.8 0.1 2.9 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Mating_N PF12731.7 OWF38235.1 - 0.026 14.6 0.8 27 5.0 0.1 3.8 3 0 0 3 3 3 0 Mating-type protein beta 1 BLOC1_2 PF10046.9 OWF38235.1 - 0.14 12.4 25.6 1 9.7 3.9 4.4 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2576 PF10845.8 OWF38235.1 - 0.18 11.4 1.1 1.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) bZIP_1 PF00170.21 OWF38235.1 - 0.18 11.9 25.9 0.68 10.1 0.1 4.8 4 1 0 4 4 4 0 bZIP transcription factor DUF4201 PF13870.6 OWF38235.1 - 0.36 10.6 29.3 0.081 12.7 8.1 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) DivIC PF04977.15 OWF38235.1 - 0.4 10.5 23.6 1.5 8.7 0.2 4.3 3 1 1 4 4 4 0 Septum formation initiator DUF1664 PF07889.12 OWF38235.1 - 0.47 10.5 24.3 0.34 10.9 4.4 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 OWF38235.1 - 0.62 10.7 14.1 0.31 11.7 0.3 4.7 4 1 1 5 5 5 0 SlyX Jnk-SapK_ap_N PF09744.9 OWF38235.1 - 0.68 10.1 38.7 0.39 10.9 6.2 3.8 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 OWF38235.1 - 0.88 9.7 26.1 0.037 14.2 3.2 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 OWF38235.1 - 1.1 9.7 26.3 4.6 7.7 0.1 4.9 3 2 2 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 OWF38235.1 - 1.2 7.6 7.5 1.3 7.5 1.4 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family ZapB PF06005.12 OWF38235.1 - 1.3 9.5 29.2 2.5 8.6 5.9 5.2 3 2 2 5 5 5 0 Cell division protein ZapB GIT_CC PF16559.5 OWF38235.1 - 1.3 8.9 16.3 2.1 8.3 1.0 4.1 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 OWF38235.1 - 2.9 7.2 35.9 0.013 14.8 10.1 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 OWF38235.1 - 3.6 8.0 42.3 1.2 9.5 11.6 4.3 1 1 4 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 OWF38235.1 - 4.3 6.6 29.5 7.6 5.8 1.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Rbsn PF11464.8 OWF38235.1 - 4.4 7.1 11.1 3.4 7.5 0.4 4.3 4 0 0 4 4 4 0 Rabenosyn Rab binding domain YabA PF06156.13 OWF38235.1 - 4.4 8.0 28.6 0.15 12.7 6.8 4.9 1 1 3 4 4 4 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OWF38235.1 - 4.7 7.2 35.9 0.3 11.1 13.9 3.6 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 OWF38235.1 - 6.4 6.7 28.9 1.8e+04 -5.3 27.9 2.7 1 1 0 1 1 0 0 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.7 OWF38235.1 - 7.7 6.7 38.4 0.62 10.2 2.6 4.0 2 2 1 3 3 3 0 Tropomyosin like COG5 PF10392.9 OWF38235.1 - 7.9 6.7 16.4 2.7 8.2 2.7 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TolA_bind_tri PF16331.5 OWF38235.1 - 9.9 6.3 17.1 5.9 7.0 4.4 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation bZIP_1 PF00170.21 OWF38236.1 - 1.1e-05 25.4 9.9 0.00054 20.0 0.4 3.6 3 0 0 3 3 3 1 bZIP transcription factor CENP-F_leu_zip PF10473.9 OWF38236.1 - 3.9e-05 23.7 28.9 0.0059 16.6 13.9 3.7 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.12 OWF38236.1 - 0.0012 19.4 9.5 0.065 13.8 0.9 3.2 1 1 2 3 3 3 1 Striatin family MMR_HSR1 PF01926.23 OWF38236.1 - 0.0015 18.6 0.0 0.0061 16.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 OWF38236.1 - 0.002 17.5 0.0 0.0053 16.1 0.0 1.7 1 0 0 1 1 1 1 Septin Cep57_CLD_2 PF14197.6 OWF38236.1 - 0.0023 18.0 3.9 0.0023 18.0 3.9 4.4 2 1 2 4 4 4 1 Centrosome localisation domain of PPC89 CASP_C PF08172.12 OWF38236.1 - 0.0036 16.7 12.3 0.048 13.0 0.2 3.3 3 0 0 3 3 3 1 CASP C terminal GTP_EFTU PF00009.27 OWF38236.1 - 0.0043 16.6 0.1 3.2 7.2 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain CCDC144C PF14915.6 OWF38236.1 - 0.0089 15.2 22.4 0.3 10.1 8.3 2.4 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region cobW PF02492.19 OWF38236.1 - 0.0095 15.5 0.8 1.3 8.6 0.0 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 OWF38236.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADIP PF11559.8 OWF38236.1 - 0.027 14.5 18.5 1.7 8.7 2.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding MCM PF00493.23 OWF38236.1 - 0.032 13.3 0.0 0.085 11.9 0.0 1.7 1 0 0 1 1 1 0 MCM P-loop domain RsgA_GTPase PF03193.16 OWF38236.1 - 0.032 14.1 10.5 0.067 13.1 0.0 3.4 3 1 0 3 3 3 0 RsgA GTPase CALCOCO1 PF07888.11 OWF38236.1 - 0.045 12.6 21.8 0.081 11.8 21.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 OWF38236.1 - 0.056 13.7 24.0 0.73 10.0 5.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_16 PF13191.6 OWF38236.1 - 0.078 13.3 0.3 0.3 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain TMF_DNA_bd PF12329.8 OWF38236.1 - 0.095 12.7 18.3 0.62 10.1 0.2 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Roc PF08477.13 OWF38236.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Jnk-SapK_ap_N PF09744.9 OWF38236.1 - 0.14 12.4 25.2 1.2 9.3 6.3 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 OWF38236.1 - 0.22 11.3 11.3 0.47 10.2 0.6 4.0 2 1 1 4 4 4 0 Septum formation initiator Phage_GP20 PF06810.11 OWF38236.1 - 0.28 11.0 15.5 0.71 9.7 2.9 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF1284 PF06935.11 OWF38236.1 - 0.32 11.5 1.7 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) DUF4472 PF14739.6 OWF38236.1 - 0.48 11.2 20.7 3.4 8.4 1.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) ATP_bind_1 PF03029.17 OWF38236.1 - 0.5 10.1 5.0 6.5 6.5 0.0 3.2 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein FPP PF05911.11 OWF38236.1 - 0.5 8.5 20.8 0.77 7.9 3.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil AAA_33 PF13671.6 OWF38236.1 - 0.76 9.9 4.5 4.8 7.3 0.0 3.3 3 1 0 3 3 2 0 AAA domain TMCO5 PF14992.6 OWF38236.1 - 0.76 9.3 20.5 0.52 9.9 4.5 2.2 1 1 1 2 2 2 0 TMCO5 family DUF1664 PF07889.12 OWF38236.1 - 0.81 9.7 20.2 0.74 9.9 2.9 3.7 2 1 1 4 4 3 0 Protein of unknown function (DUF1664) AAA_23 PF13476.6 OWF38236.1 - 0.95 9.9 0.0 0.95 9.9 0.0 2.7 2 1 0 2 2 1 0 AAA domain LPP PF04728.13 OWF38236.1 - 1 9.8 6.6 21 5.6 0.2 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SHE3 PF17078.5 OWF38236.1 - 1.3 8.7 17.2 0.21 11.3 3.3 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 YjbH PF06082.11 OWF38236.1 - 1.4 7.6 10.4 0.64 8.8 3.1 2.0 1 1 1 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Tropomyosin_1 PF12718.7 OWF38236.1 - 1.6 8.8 21.3 1.9 8.6 0.7 3.2 1 1 1 3 3 3 0 Tropomyosin like APG6_N PF17675.1 OWF38236.1 - 1.9 9.0 22.9 9.6 6.7 10.9 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region ABC_tran PF00005.27 OWF38236.1 - 1.9 9.0 0.0 1.9 9.0 0.0 2.8 2 1 0 2 2 1 0 ABC transporter DUF724 PF05266.14 OWF38236.1 - 2.6 7.9 14.5 12 5.7 4.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 OWF38236.1 - 5.9 6.3 24.4 23 4.3 17.3 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 BRE1 PF08647.11 OWF38236.1 - 6.3 6.9 11.9 14 5.9 1.6 3.0 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SOGA PF11365.8 OWF38236.1 - 7 7.8 14.1 24 6.1 7.4 3.5 2 2 0 2 2 2 0 Protein SOGA CENP-H PF05837.12 OWF38236.1 - 7.4 7.0 21.1 2.5 8.6 3.1 3.5 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF4446 PF14584.6 OWF38236.1 - 9.3 6.2 8.2 24 4.9 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DivIC PF04977.15 OWF38237.1 - 0.00014 21.6 3.3 0.00014 21.6 3.3 14.6 5 4 10 16 16 16 1 Septum formation initiator Spc7 PF08317.11 OWF38237.1 - 0.00078 18.4 21.7 0.00078 18.4 21.7 6.7 2 1 4 7 7 7 4 Spc7 kinetochore protein KASH_CCD PF14662.6 OWF38237.1 - 0.0032 17.3 35.5 0.0032 17.3 35.5 7.7 3 2 4 8 8 8 1 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 OWF38237.1 - 0.01 15.8 8.2 0.01 15.8 8.2 13.3 5 5 8 13 13 13 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 OWF38237.1 - 0.013 15.6 13.4 0.013 15.6 13.4 8.6 2 1 3 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBCC PF07986.12 OWF38238.1 - 7.3e-44 148.4 2.9 1.1e-43 147.8 2.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 OWF38238.1 - 3.8e-33 114.4 7.6 6.4e-33 113.7 7.6 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain NinF PF05810.12 OWF38238.1 - 0.16 11.8 1.4 0.54 10.2 0.0 2.5 3 0 0 3 3 3 0 NinF protein Tetraspanin PF00335.20 OWF38240.1 - 5.1e-22 78.7 9.3 7.2e-22 78.2 9.3 1.2 1 0 0 1 1 1 1 Tetraspanin family Prominin PF05478.11 OWF38240.1 - 0.028 12.4 2.6 0.042 11.8 2.6 1.2 1 0 0 1 1 1 0 Prominin Tetraspanin PF00335.20 OWF38242.1 - 8.4e-22 78.0 9.4 1.2e-21 77.5 9.4 1.3 1 0 0 1 1 1 1 Tetraspanin family Prominin PF05478.11 OWF38242.1 - 0.034 12.1 1.7 0.054 11.5 1.7 1.2 1 0 0 1 1 1 0 Prominin Keratin_assoc PF09775.9 OWF38242.1 - 0.073 12.7 3.2 0.13 11.9 0.6 2.4 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Patched PF02460.18 OWF38243.1 - 6.2e-16 57.7 5.6 1.5e-15 56.5 5.6 1.5 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF38243.1 - 1.3e-13 51.1 6.9 3.4e-13 49.7 6.9 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Pox_I5 PF04713.12 OWF38243.1 - 4.4 7.4 5.7 0.68 10.0 0.6 2.3 2 0 0 2 2 2 0 Poxvirus protein I5 NBP1 PF08537.10 OWF38244.1 - 0.0064 15.9 4.6 1.5 8.1 1.0 2.9 1 1 1 2 2 2 2 Fungal Nap binding protein NBP1 TraI_2B PF18340.1 OWF38244.1 - 0.025 14.6 2.1 16 5.6 0.2 4.1 1 1 4 5 5 5 0 DNA relaxase TraI 2B/2B-like domain DUF2016 PF09436.10 OWF38244.1 - 0.058 13.2 0.2 30 4.5 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF2016) Atg31 PF09795.9 OWF38244.1 - 0.075 13.0 4.3 6.5 6.7 4.3 2.5 1 1 0 1 1 1 0 Autophagy-related protein 31 DUF4573 PF15140.6 OWF38244.1 - 1.2 8.9 11.4 0.78 9.5 7.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4573) Patched PF02460.18 OWF38245.1 - 1.2e-07 30.3 14.4 1.6e-07 29.9 14.4 1.1 1 0 0 1 1 1 1 Patched family MMPL PF03176.15 OWF38245.1 - 4.9e-06 25.7 7.4 7.2e-06 25.1 7.4 1.2 1 0 0 1 1 1 1 MMPL family Sterol-sensing PF12349.8 OWF38245.1 - 0.00061 19.7 10.7 0.0009 19.1 10.7 1.2 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation TMEM18 PF14770.6 OWF38245.1 - 2.4 8.2 8.0 10 6.1 2.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 18 zf-C4 PF00105.18 OWF38246.1 - 5e-45 151.8 40.1 4e-27 94.5 13.8 2.7 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) GLTT PF01744.20 OWF38248.1 - 1.3 8.9 24.0 25 4.8 0.1 7.3 8 0 0 8 8 8 0 GLTT repeat (6 copies) GLTT PF01744.20 OWF38249.1 - 0.29 10.9 5.4 9.2 6.1 0.1 3.3 3 1 0 3 3 3 0 GLTT repeat (6 copies) GLTT PF01744.20 OWF38250.1 - 0.22 11.3 8.7 10 6.0 0.2 3.9 4 0 0 4 4 4 0 GLTT repeat (6 copies) PseudoU_synth_2 PF00849.22 OWF38250.1 - 0.45 10.6 3.9 18 5.4 0.2 3.0 2 1 2 4 4 4 0 RNA pseudouridylate synthase Bclx_interact PF08945.10 OWF38251.1 - 0.00021 21.0 0.2 0.00054 19.7 0.2 1.8 1 0 0 1 1 1 1 Bcl-x interacting, BH3 domain Bcl-2_BAD PF10514.9 OWF38251.1 - 0.0027 18.2 0.2 0.0027 18.2 0.2 2.0 2 2 0 2 2 2 1 Pro-apoptotic Bcl-2 protein, BAD Pkinase PF00069.25 OWF38252.1 - 3.5e-17 62.6 0.0 9.3e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38252.1 - 0.002 17.5 0.4 0.0076 15.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase LIN52 PF10044.9 OWF38253.1 - 5.4e-37 126.4 0.1 6.2e-37 126.2 0.1 1.0 1 0 0 1 1 1 1 Retinal tissue protein HEPN_Cthe2314 PF18730.1 OWF38253.1 - 0.16 12.0 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Cthe_2314-like HEPN Aldedh PF00171.22 OWF38254.1 - 1.4e-134 449.1 0.1 1.6e-134 448.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OWF38254.1 - 0.037 13.1 0.1 0.074 12.1 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) RRF PF01765.19 OWF38254.1 - 0.069 13.1 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Glyco_transf_43 PF03360.16 OWF38255.1 - 8.9e-75 251.0 0.2 8.9e-75 251.0 0.2 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 43 Fib_alpha PF08702.10 OWF38255.1 - 0.015 15.4 3.5 0.029 14.6 3.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1090 PF06476.12 OWF38255.1 - 0.019 15.1 0.8 0.055 13.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Spc7 PF08317.11 OWF38255.1 - 0.032 13.1 2.7 0.056 12.3 2.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CHASE3 PF05227.13 OWF38255.1 - 0.092 12.7 1.7 0.16 11.9 1.7 1.3 1 0 0 1 1 1 0 CHASE3 domain Macro PF01661.21 OWF38256.1 - 1.9e-27 95.7 1.7 2.6e-27 95.2 0.2 2.0 2 0 0 2 2 2 1 Macro domain WD40 PF00400.32 OWF38257.1 - 9.9e-27 92.7 25.6 2e-05 25.3 6.4 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF38257.1 - 2.2e-07 31.0 5.0 1 9.7 0.0 6.0 7 0 0 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF38257.1 - 0.0012 18.3 0.2 0.96 8.7 0.0 3.7 3 1 1 4 4 4 1 WD40-like domain PQQ PF01011.21 OWF38257.1 - 0.011 15.6 0.3 0.84 9.7 0.0 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat Nup160 PF11715.8 OWF38257.1 - 0.02 13.6 0.1 2.1 6.9 0.0 3.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 MoaC PF01967.21 OWF38258.1 - 2.7e-54 182.9 4.6 4.3e-54 182.3 4.6 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 OWF38258.1 - 1.5e-41 141.3 0.0 2.9e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OWF38258.1 - 1e-29 104.0 0.1 2e-29 103.1 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OWF38258.1 - 4.2e-10 40.0 0.0 1.2e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OWF38258.1 - 5.3e-05 23.3 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain G-patch PF01585.23 OWF38259.1 - 4.5e-13 48.9 1.4 9e-13 47.9 1.4 1.5 1 0 0 1 1 1 1 G-patch domain DUF4187 PF13821.6 OWF38259.1 - 1.8e-12 46.9 2.5 6.2e-12 45.1 2.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch_2 PF12656.7 OWF38259.1 - 1e-05 25.5 2.9 1e-05 25.5 2.9 2.2 1 1 1 2 2 2 1 G-patch domain Myc_N PF01056.18 OWF38259.1 - 0.77 9.6 13.4 0.021 14.7 6.7 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Imm74 PF15603.6 OWF38260.1 - 3.4e-06 27.1 72.4 19 5.5 0.1 18.3 2 2 21 23 23 23 13 Immunity protein 74 DUF2685 PF10886.8 OWF38260.1 - 0.013 15.7 114.9 74 3.6 0.1 37.4 4 3 39 44 44 44 0 Protein of unknown function (DUF2685) DUF2277 PF10041.9 OWF38260.1 - 0.013 15.8 0.5 1.6e+02 2.7 0.0 8.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) Cast PF10174.9 OWF38260.1 - 3.4 5.8 10.8 1.3e+02 0.5 0.1 6.4 1 1 15 17 17 17 0 RIM-binding protein of the cytomatrix active zone ABC_tran PF00005.27 OWF38261.1 - 2.6e-62 209.4 0.0 1e-23 84.4 0.0 3.8 3 1 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 OWF38261.1 - 3.2e-57 194.3 30.4 2.5e-30 106.1 9.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 OWF38261.1 - 2.1e-11 43.9 0.6 0.014 15.5 0.0 3.5 3 0 0 3 3 3 3 50S ribosome-binding GTPase AAA_21 PF13304.6 OWF38261.1 - 6.3e-07 29.5 1.0 0.57 9.9 0.1 4.0 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OWF38261.1 - 7e-07 28.9 3.7 0.47 10.2 0.1 3.5 3 0 0 3 3 3 3 P-loop containing region of AAA domain DUF87 PF01935.17 OWF38261.1 - 3e-06 27.5 7.6 0.31 11.1 0.1 3.9 4 0 0 4 4 3 3 Helicase HerA, central domain AAA_23 PF13476.6 OWF38261.1 - 3.1e-06 27.8 0.7 1.1 9.7 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 OWF38261.1 - 5.4e-06 26.7 0.1 2.3 8.5 0.1 3.9 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 OWF38261.1 - 1.2e-05 24.8 4.1 1.1 8.5 0.1 3.4 3 0 0 3 3 3 3 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 OWF38261.1 - 2e-05 24.6 4.2 0.093 12.6 0.2 3.5 3 0 0 3 3 3 1 RsgA GTPase SMC_N PF02463.19 OWF38261.1 - 2.9e-05 23.6 9.2 3.2 7.1 0.0 5.2 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 OWF38261.1 - 0.00023 20.3 5.9 0.26 10.2 0.1 3.2 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OWF38261.1 - 0.0004 20.8 0.1 16 5.8 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 OWF38261.1 - 0.0004 19.9 4.6 1.8 8.1 0.1 3.7 4 0 0 4 4 3 1 P-loop containing dynein motor region Septin PF00735.18 OWF38261.1 - 0.00067 19.0 0.1 10 5.3 0.0 3.3 3 0 0 3 3 3 0 Septin DUF815 PF05673.13 OWF38261.1 - 0.00071 18.8 0.1 5.6 6.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OWF38261.1 - 0.0017 18.7 0.2 30 5.1 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 OWF38261.1 - 0.0019 18.0 0.0 3 7.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 OWF38261.1 - 0.0022 17.0 6.3 3 6.7 0.1 3.8 4 0 0 4 4 4 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 OWF38261.1 - 0.0024 18.4 0.0 15 6.1 0.0 3.8 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 OWF38261.1 - 0.0028 17.4 1.0 11 5.6 0.0 3.8 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 OWF38261.1 - 0.0043 17.3 1.3 11 6.3 0.1 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 OWF38261.1 - 0.0048 16.4 1.3 6.5 6.1 0.0 3.4 3 0 0 3 3 3 0 Poxvirus A32 protein Zeta_toxin PF06414.12 OWF38261.1 - 0.0057 16.0 1.0 3.2 7.0 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin NB-ARC PF00931.22 OWF38261.1 - 0.011 15.0 3.6 2.5 7.2 0.1 3.3 3 0 0 3 3 3 0 NB-ARC domain Dynamin_N PF00350.23 OWF38261.1 - 0.018 15.1 7.3 0.034 14.2 0.1 3.3 3 0 0 3 3 3 0 Dynamin family AAA_15 PF13175.6 OWF38261.1 - 0.018 14.7 0.5 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 OWF38261.1 - 0.019 14.7 0.1 20 4.9 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OWF38261.1 - 0.024 14.6 3.9 6.3 6.7 0.2 3.4 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 OWF38261.1 - 0.043 13.5 1.0 16 5.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 OWF38261.1 - 0.065 13.0 1.6 3 7.6 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 OWF38261.1 - 0.082 12.1 0.0 1.7 7.8 0.0 2.8 3 0 0 3 3 3 0 KAP family P-loop domain T2SSE PF00437.20 OWF38261.1 - 0.21 10.6 3.3 18 4.3 0.1 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_10 PF12846.7 OWF38261.1 - 0.25 10.2 1.4 11 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain DUF2075 PF09848.9 OWF38261.1 - 0.32 10.2 1.7 35 3.5 0.0 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 OWF38261.1 - 0.73 9.8 4.7 7.1 6.7 0.1 3.5 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 OWF38261.1 - 1.2 8.9 2.8 34 4.2 0.1 3.2 4 0 0 4 4 3 0 DEAD/DEAH box helicase p450 PF00067.22 OWF38262.1 - 1.8e-60 205.0 0.0 2.6e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4517 PF15006.6 OWF38263.1 - 6.7e-42 143.3 0.9 7.9e-42 143.1 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) NHL PF01436.21 OWF38264.1 - 3e-22 77.4 9.0 1.9e-05 24.4 0.0 7.0 7 0 0 7 7 7 4 NHL repeat DUF5128 PF17170.4 OWF38264.1 - 8.5e-05 21.9 0.1 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 6-bladed beta-propeller SGL PF08450.12 OWF38264.1 - 0.00012 21.7 0.0 0.02 14.5 0.0 2.9 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region DUF4934 PF16288.5 OWF38264.1 - 0.00042 20.2 0.2 0.028 14.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4934) SBBP PF06739.11 OWF38264.1 - 0.0049 16.8 0.9 1.1 9.3 0.1 2.6 2 0 0 2 2 2 2 Beta-propeller repeat MukE PF04288.13 OWF38264.1 - 0.071 12.0 0.2 0.071 12.0 0.2 1.8 2 0 0 2 2 2 0 MukE-like family HEAT_2 PF13646.6 OWF38265.1 - 2.7e-22 78.9 0.7 1.5e-08 34.9 0.3 5.2 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 OWF38265.1 - 2.9e-08 33.3 3.6 1.4 9.4 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat DUF1543 PF07566.12 OWF38265.1 - 0.0063 16.2 0.1 5.2 6.9 0.0 2.7 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1543) HEAT_EZ PF13513.6 OWF38265.1 - 0.015 15.8 2.2 19 5.9 0.0 5.2 6 0 0 6 6 6 0 HEAT-like repeat Methyltransf_23 PF13489.6 OWF38266.1 - 1.1e-10 41.5 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF38266.1 - 2e-10 41.2 0.0 3.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF38266.1 - 2.2e-10 41.1 0.0 3.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF38266.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OWF38266.1 - 8.8e-07 28.8 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF38266.1 - 0.0026 18.5 0.0 0.0041 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OWF38266.1 - 0.0027 16.8 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.20 OWF38266.1 - 0.016 14.3 0.1 1.3 8.1 0.0 2.2 1 1 1 2 2 2 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OWF38266.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 OWF38266.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_PK PF05891.12 OWF38266.1 - 0.098 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Aldo_ket_red PF00248.21 OWF38267.1 - 7.6e-59 199.3 0.0 1e-58 198.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 OWF38268.1 - 4.8e-109 364.1 0.0 1.3e-53 182.2 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family NRN1 PF15056.6 OWF38268.1 - 0.0012 18.9 0.1 2.9 8.1 0.0 2.6 2 0 0 2 2 2 2 Neuritin protein family Prenyltransf PF01255.19 OWF38268.1 - 0.068 12.7 0.0 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Gag_p19 PF02228.16 OWF38268.1 - 0.13 12.8 0.0 20 5.7 0.0 2.5 2 0 0 2 2 2 0 Major core protein p19 Aldo_ket_red PF00248.21 OWF38269.1 - 8.3e-55 186.0 0.0 1.1e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 OWF38270.1 - 2.5e-51 174.6 0.0 3.5e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 OWF38271.1 - 6.7e-44 150.3 0.0 8.9e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_11 PF01531.16 OWF38272.1 - 7.9e-43 146.8 5.8 7.2e-42 143.6 5.7 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 11 SNARE PF05739.19 OWF38272.1 - 0.13 12.2 2.6 0.23 11.5 2.6 1.3 1 0 0 1 1 1 0 SNARE domain CybS PF05328.12 OWF38273.1 - 3.9e-22 78.4 0.5 6e-22 77.8 0.5 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Hydrolase_like PF13242.6 OWF38274.1 - 5e-21 74.6 0.4 1.1e-19 70.3 0.1 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OWF38274.1 - 5.7e-15 55.3 0.0 1.3e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OWF38274.1 - 2.6e-07 31.1 0.4 0.0029 17.9 0.0 3.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OWF38274.1 - 1.5e-06 28.4 0.0 0.00012 22.2 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 OWF38274.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SPATA24 PF15175.6 OWF38275.1 - 1.5e-44 152.0 33.2 8.2e-42 143.1 27.4 2.0 1 1 1 2 2 2 2 Spermatogenesis-associated protein 24 Methyltransf_15 PF09445.10 OWF38275.1 - 0.00071 19.2 0.2 0.015 14.9 0.0 2.4 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase DUF4407 PF14362.6 OWF38275.1 - 0.0068 15.8 15.3 0.01 15.2 15.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 OWF38275.1 - 0.028 14.0 20.3 0.038 13.6 20.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MMTV_SAg PF01054.17 OWF38275.1 - 0.049 13.2 3.3 0.078 12.5 3.3 1.5 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Lebercilin PF15619.6 OWF38275.1 - 0.17 11.6 29.9 0.025 14.2 15.4 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Ly49 PF08391.10 OWF38275.1 - 1.4 9.3 18.4 1.1 9.7 10.0 2.5 1 1 2 3 3 3 0 Ly49-like protein, N-terminal region DUF948 PF06103.11 OWF38275.1 - 1.5 9.2 6.8 0.36 11.1 2.6 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 OWF38275.1 - 1.7 8.7 26.9 4.7 7.3 8.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3811 PF11656.8 OWF38275.1 - 3 8.3 12.6 0.14 12.6 3.3 2.8 1 1 0 2 2 2 0 YjbD family (DUF3811) DUF1664 PF07889.12 OWF38275.1 - 3 7.9 13.0 0.9 9.6 6.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nas2_N PF18265.1 OWF38275.1 - 4 7.4 8.7 2.1 8.3 1.9 3.3 2 2 0 3 3 3 0 Nas2 N_terminal domain FAM76 PF16046.5 OWF38275.1 - 6.1 6.1 20.2 5.1 6.4 18.7 1.4 1 1 0 1 1 1 0 FAM76 protein Sushi PF00084.20 OWF38277.1 - 2.4e-36 124.1 41.1 1.2e-06 29.0 1.9 6.7 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) HRM PF02793.22 OWF38277.1 - 0.017 15.4 19.7 0.16 12.3 0.1 5.5 5 1 1 6 6 6 0 Hormone receptor domain zf-RING_2 PF13639.6 OWF38279.1 - 2.2e-10 40.7 10.6 5.2e-10 39.5 10.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF38279.1 - 2.6e-05 23.9 10.7 6.3e-05 22.6 10.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OWF38279.1 - 8.1e-05 22.6 7.9 0.00018 21.4 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF38279.1 - 0.0006 19.6 10.6 0.0014 18.5 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF38279.1 - 0.00078 19.7 11.8 0.0041 17.4 11.8 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF38279.1 - 0.0009 19.1 9.1 0.0021 17.9 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF38279.1 - 0.0046 16.9 8.5 0.0091 15.9 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain SOG2 PF10428.9 OWF38279.1 - 0.011 14.9 3.0 0.018 14.3 3.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-ANAPC11 PF12861.7 OWF38279.1 - 0.038 14.0 10.1 0.036 14.1 7.7 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OWF38279.1 - 1.1 9.5 10.2 1.3 9.3 8.0 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OWF38279.1 - 2.6 8.3 10.0 6.8 6.9 10.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 OWF38279.1 - 4 7.1 11.1 11 5.7 9.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MNNL PF07657.13 OWF38279.1 - 8.6 6.5 8.5 5.7 7.0 0.5 2.6 2 0 0 2 2 2 0 N terminus of Notch ligand NRBF2_MIT PF17169.4 OWF38280.1 - 2.6e-19 69.2 6.5 5.5e-19 68.2 6.5 1.5 1 0 0 1 1 1 1 MIT domain of nuclear receptor-binding factor 2 NRBF2 PF08961.10 OWF38280.1 - 0.00029 20.5 4.6 0.00029 20.5 4.6 2.1 2 1 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator MIT PF04212.18 OWF38280.1 - 0.0051 16.9 0.3 0.011 15.8 0.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF1978 PF09321.10 OWF38280.1 - 0.021 14.1 3.6 0.03 13.6 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Sec20 PF03908.13 OWF38281.1 - 5.1e-23 80.8 0.8 5.1e-23 80.8 0.8 1.9 2 1 0 2 2 2 1 Sec20 LMBR1 PF04791.16 OWF38281.1 - 0.038 12.9 3.4 0.044 12.7 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GWT1 PF06423.12 OWF38282.1 - 0.007 16.5 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 GWT1 Polysacc_synt_C PF14667.6 OWF38282.1 - 0.65 10.0 13.3 1.2 9.2 11.6 1.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF2207 PF09972.9 OWF38282.1 - 2.5 6.7 14.4 0.031 13.0 0.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 OWF38282.1 - 5.7 6.7 12.5 0.13 12.0 0.4 2.0 1 1 1 2 2 2 0 Fatty acid desaturase RRM_7 PF16367.5 OWF38283.1 - 1.5e-36 124.4 0.0 9e-35 118.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 OWF38283.1 - 1.6e-20 73.0 6.4 3.4e-20 72.0 6.4 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 OWF38283.1 - 2.3e-11 43.3 0.0 3.3e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.21 OWF38283.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family zf-B_box PF00643.24 OWF38283.1 - 1.7 8.9 7.7 3.4 7.9 7.7 1.4 1 0 0 1 1 1 0 B-box zinc finger RINGv PF12906.7 OWF38284.1 - 5.3e-15 55.3 11.6 9.1e-15 54.5 11.6 1.4 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.9 OWF38284.1 - 0.0082 15.9 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.6 OWF38284.1 - 0.021 15.1 9.1 0.021 15.1 9.1 2.0 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.8 OWF38284.1 - 0.19 12.0 13.1 0.038 14.2 9.5 1.7 2 0 0 2 2 2 0 FANCL C-terminal domain Claudin_2 PF13903.6 OWF38285.1 - 1.8e-08 34.4 2.5 2.5e-08 33.9 2.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction ERGIC_N PF13850.6 OWF38285.1 - 0.63 10.4 5.3 0.26 11.7 0.7 2.4 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF5412 PF17428.2 OWF38285.1 - 0.68 9.8 2.2 0.43 10.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5412) Glyco_transf_11 PF01531.16 OWF38286.1 - 3.2e-34 118.5 2.4 5.8e-34 117.7 2.4 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 OWF38286.1 - 5e-05 23.2 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ost5 PF05251.12 OWF38286.1 - 0.06 13.6 0.5 0.14 12.4 0.5 1.6 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 HDNR PF15115.6 OWF38287.1 - 6.5e-31 107.9 4.2 7.7e-31 107.7 3.5 1.4 1 1 1 2 2 2 1 Domain of unknown function with conserved HDNR motif CLTH PF10607.9 OWF38288.1 - 1.4e-31 109.4 1.4 2.4e-31 108.6 1.4 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OWF38288.1 - 0.0089 16.0 1.0 0.077 13.0 0.1 2.8 2 1 0 2 2 2 1 RING-type zinc-finger LisH PF08513.11 OWF38288.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 LisH 2-Hacid_dh_C PF02826.19 OWF38289.1 - 8.7e-57 191.3 0.0 1.3e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF38289.1 - 2.6e-28 98.3 0.0 3.2e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OWF38289.1 - 0.00046 20.4 0.0 0.00078 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PseudoU_synth_1 PF01416.20 OWF38290.1 - 2.2e-11 44.2 0.0 2.8e-09 37.4 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase Macro PF01661.21 OWF38291.1 - 1.7e-84 279.7 0.9 1.5e-33 115.3 0.1 4.8 4 0 0 4 4 4 4 Macro domain PARP PF00644.20 OWF38291.1 - 1.7e-26 93.1 1.4 6.5e-26 91.1 1.4 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 OWF38291.1 - 1e-08 35.6 0.7 4.2e-08 33.7 0.7 2.2 1 0 0 1 1 1 1 WWE domain RRM_1 PF00076.22 OWF38291.1 - 0.00071 19.4 0.8 3 7.7 0.0 5.2 5 0 0 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CobT PF06213.12 OWF38291.1 - 0.0087 15.5 0.0 0.0087 15.5 0.0 2.8 3 0 0 3 3 3 1 Cobalamin biosynthesis protein CobT RRM_occluded PF16842.5 OWF38291.1 - 0.039 13.8 0.0 0.35 10.7 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif PDZ PF00595.24 OWF38292.1 - 1.5e-12 47.7 0.0 5.4e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 OWF38292.1 - 4.1e-08 32.9 0.0 8.6e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF38292.1 - 0.1 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 PDZ domain RBD PF02196.15 OWF38293.1 - 9.6e-37 124.9 0.0 2.4e-22 78.8 0.0 2.6 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.19 OWF38293.1 - 2.1e-29 102.2 0.8 2.1e-29 102.2 0.8 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain GoLoco PF02188.17 OWF38293.1 - 1.8e-07 30.5 1.1 4.2e-07 29.3 1.1 1.7 1 0 0 1 1 1 1 GoLoco motif TUG-UBL1 PF11470.8 OWF38293.1 - 0.003 17.7 0.2 0.72 10.1 0.0 2.9 3 0 0 3 3 3 2 TUG ubiquitin-like domain Macro PF01661.21 OWF38294.1 - 1.6e-50 170.1 6.6 1.6e-16 60.4 0.0 4.9 5 0 0 5 5 5 4 Macro domain PARP PF00644.20 OWF38294.1 - 7.8e-21 74.6 0.9 9.2e-20 71.1 0.9 2.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 OWF38294.1 - 0.0002 21.9 0.5 0.0013 19.3 0.1 2.7 2 0 0 2 2 2 1 WWE domain PepSY_2 PF13670.6 OWF38294.1 - 0.0081 16.1 0.0 0.033 14.2 0.0 2.1 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain NUMOD4 PF07463.11 OWF38294.1 - 0.012 15.8 0.1 0.052 13.8 0.1 2.1 1 0 0 1 1 1 0 NUMOD4 motif MycE_N PF17843.1 OWF38294.1 - 0.012 16.1 0.3 0.045 14.2 0.1 2.1 2 0 0 2 2 2 0 MycE methyltransferase N-terminal DUF681 PF05080.12 OWF38294.1 - 0.16 12.6 0.2 0.4 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF681) WD40 PF00400.32 OWF38295.1 - 1.3e-18 67.0 10.2 2.9e-05 24.7 0.9 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF38295.1 - 2.3e-05 24.6 0.0 1.3 9.3 0.0 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF38296.1 - 2.3e-18 66.2 40.4 6.6e-05 23.6 0.2 12.2 12 0 0 12 12 12 8 WD domain, G-beta repeat CPSF_A PF03178.15 OWF38296.1 - 1.5e-06 27.8 0.0 0.00022 20.6 0.0 2.8 2 0 0 2 2 2 2 CPSF A subunit region Nucleoporin_N PF08801.11 OWF38296.1 - 0.0094 14.7 1.9 0.083 11.6 0.3 3.0 3 1 1 4 4 4 1 Nup133 N terminal like SRCR PF00530.18 OWF38297.1 - 3.4e-148 483.2 49.2 1.2e-26 93.1 0.4 8.5 8 0 0 8 8 8 8 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 OWF38297.1 - 1.4e-36 126.6 11.1 1.4e-36 126.6 11.1 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain SRCR_2 PF15494.6 OWF38297.1 - 1.5e-28 99.2 40.2 0.00011 22.6 2.4 8.3 8 0 0 8 8 8 7 Scavenger receptor cysteine-rich domain CUB PF00431.20 OWF38297.1 - 9.4e-11 42.0 0.0 2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 CUB domain Hepsin-SRCR PF09272.10 OWF38297.1 - 8.5e-08 32.7 15.0 0.19 12.3 1.7 7.6 7 1 0 7 7 7 1 Hepsin, SRCR domain 7tm_1 PF00001.21 OWF38298.1 - 5.4e-77 258.7 7.6 8.3e-77 258.1 7.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF38298.1 - 2.5e-14 53.3 7.3 5.3e-09 35.8 2.9 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF38298.1 - 1.7e-07 31.1 5.3 1.7e-07 31.1 5.3 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF38298.1 - 0.00019 21.3 2.4 0.00019 21.3 2.4 2.1 2 0 0 2 2 2 1 Olfactory receptor tify PF06200.14 OWF38299.1 - 2.7e-07 29.8 0.1 1.1e+02 2.3 0.0 12.6 19 0 0 19 19 19 0 tify domain YscW PF09619.10 OWF38299.1 - 0.00033 21.0 0.2 29 5.1 0.0 6.0 4 2 2 7 7 7 1 Type III secretion system lipoprotein chaperone (YscW) Tudor_FRX1 PF18336.1 OWF38299.1 - 0.075 13.0 7.5 1.2e+02 2.7 0.0 7.3 6 0 0 6 6 6 0 Fragile X mental retardation Tudor domain FAM184 PF15665.5 OWF38300.1 - 3.6e-63 213.1 41.3 3.6e-63 213.1 41.3 7.4 2 1 4 6 6 6 2 Family with sequence similarity 184, A and B DUF2746 PF10874.8 OWF38300.1 - 0.063 13.7 3.9 0.18 12.3 1.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) 7tm_1 PF00001.21 OWF38301.1 - 1.9e-36 125.8 6.4 2.3e-36 125.5 6.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF38301.1 - 0.002 17.9 5.0 0.0044 16.8 5.0 1.5 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF38301.1 - 0.005 16.3 18.0 0.0087 15.5 7.7 2.6 2 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF38301.1 - 0.41 9.9 16.2 0.19 11.0 3.5 2.7 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srw Myosin_N PF02736.19 OWF38302.1 - 3.4e-05 23.6 0.0 49 3.9 0.0 7.0 8 0 0 8 8 8 0 Myosin N-terminal SH3-like domain SpmSyn_N PF17950.1 OWF38302.1 - 0.02 15.0 5.6 36 4.6 0.0 5.6 2 2 4 7 7 7 0 S-adenosylmethionine decarboxylase N -terminal BiPBP_C PF06832.12 OWF38302.1 - 4.1 7.5 11.1 30 4.8 0.3 4.8 3 2 4 7 7 7 0 Penicillin-Binding Protein C-terminus Family NHL PF01436.21 OWF38302.1 - 5.5 7.2 13.1 19 5.5 0.0 6.9 10 0 0 10 10 10 0 NHL repeat HSP70 PF00012.20 OWF38303.1 - 3.3e-121 405.4 0.8 4e-121 405.1 0.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF38303.1 - 9.9e-18 64.0 0.7 7.9e-17 61.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 OWF38303.1 - 0.00012 21.2 0.2 0.0002 20.5 0.2 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Raco_middle PF17651.1 OWF38303.1 - 0.00017 21.3 3.0 0.009 15.7 0.0 3.1 2 1 0 3 3 3 1 RACo middle region FtsA PF14450.6 OWF38303.1 - 0.0002 21.7 0.1 0.085 13.3 0.0 2.8 2 2 0 2 2 2 2 Cell division protein FtsA StbA PF06406.11 OWF38303.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.6 1 0 0 1 1 1 0 StbA protein DUF1439 PF07273.12 OWF38303.1 - 0.065 13.1 1.2 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1439) RbsD_FucU PF05025.13 OWF38304.1 - 2.4e-41 141.3 0.0 2.7e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family Arena_ncap_C PF17290.2 OWF38304.1 - 0.18 11.1 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain Creatinase_N_2 PF16189.5 OWF38305.1 - 3e-47 160.7 0.0 4.8e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OWF38305.1 - 4.5e-46 157.2 0.0 6.3e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 OWF38305.1 - 1.5e-16 61.2 0.0 8.3e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 OWF38305.1 - 2.2e-07 30.8 0.0 1.6e-06 28.1 0.1 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Homeodomain PF00046.29 OWF38306.1 - 1.7e-05 24.6 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Homeodomain Complex1_LYR PF05347.15 OWF38306.1 - 0.098 12.7 0.0 0.098 12.7 0.0 1.1 1 0 0 1 1 1 0 Complex 1 protein (LYR family) GMAP PF06540.11 OWF38307.1 - 8.5e-17 61.0 0.0 1.7e+02 2.3 0.0 19.3 25 0 0 25 25 25 0 Galanin message associated peptide (GMAP) EURL PF06937.11 OWF38307.1 - 5.6e-09 35.8 0.0 61 2.9 0.0 10.4 1 1 11 13 13 13 0 EURL protein DUF5549 PF17703.1 OWF38307.1 - 2.6e-08 33.7 22.7 38 3.9 0.0 13.0 7 2 9 17 17 17 6 Family of unknown function (DUF5549) Ank_2 PF12796.7 OWF38308.1 - 6.2e-42 142.1 0.0 2.5e-11 44.0 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38308.1 - 4.1e-33 113.3 1.2 1.2e-07 32.1 0.1 6.6 4 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF38308.1 - 2.8e-27 93.9 5.5 0.0024 18.2 0.0 8.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 OWF38308.1 - 3.6e-27 91.4 0.1 0.003 17.9 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 OWF38308.1 - 1.1e-25 89.4 0.1 3.4e-07 30.4 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) F-box-like PF12937.7 OWF38310.1 - 1.2e-08 34.7 1.4 8.7e-08 31.9 0.6 2.3 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 OWF38310.1 - 1.2e-06 29.1 16.3 0.13 13.2 0.0 6.3 8 0 0 8 8 8 4 WD domain, G-beta repeat F-box PF00646.33 OWF38310.1 - 0.0001 22.1 0.4 0.00023 20.9 0.4 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 OWF38310.1 - 0.0014 18.1 0.0 0.049 13.0 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain SBP PF03110.14 OWF38310.1 - 0.12 12.7 0.4 0.45 10.8 0.1 2.1 2 0 0 2 2 2 0 SBP domain Suv3_N PF18114.1 OWF38311.1 - 3.4e-23 82.0 0.0 8.5e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Suv3 helical N-terminal domain SUV3_C PF12513.8 OWF38311.1 - 5.1e-13 48.7 0.3 1.6e-12 47.1 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 OWF38311.1 - 1.3e-09 38.4 0.0 3.9e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 OWF38311.1 - 2.7e-06 27.2 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 AAA_7 PF12775.7 OWF38311.1 - 0.024 14.1 0.1 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MFS_1 PF07690.16 OWF38312.1 - 3.2e-05 23.0 38.9 0.00031 19.8 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 OWF38314.1 - 7.8e-20 70.2 36.4 4.1e-05 23.8 1.6 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF38314.1 - 8.4e-16 57.6 30.8 0.00012 22.3 2.7 6.0 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF38314.1 - 2.4e-15 55.9 31.6 0.0044 17.7 0.9 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF38314.1 - 3.6e-06 27.1 14.2 0.057 13.7 0.1 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF38314.1 - 0.00033 20.6 21.8 0.23 11.5 0.1 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 OWF38314.1 - 0.014 15.7 14.3 0.035 14.4 0.4 3.8 2 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 OWF38314.1 - 0.015 15.5 4.3 10 6.5 0.0 4.7 3 1 1 4 4 4 0 zinc-ribbon C1_1 PF00130.22 OWF38314.1 - 0.019 14.8 10.5 0.15 11.9 0.1 3.5 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.18 OWF38314.1 - 0.02 15.2 2.8 0.6 10.4 0.0 3.1 3 0 0 3 3 3 0 BolA-like protein zinc_ribbon_13 PF09855.9 OWF38314.1 - 0.02 15.0 7.0 48 4.2 0.0 5.7 2 1 4 7 7 7 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C2H2_11 PF16622.5 OWF38314.1 - 0.023 14.5 28.5 0.042 13.6 0.2 5.3 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 OWF38314.1 - 0.03 14.4 15.3 0.2 11.8 4.6 4.2 2 1 2 4 4 4 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 OWF38314.1 - 0.11 13.3 12.7 2.4 9.0 0.7 3.0 2 1 0 2 2 2 0 zinc-ribbon family C1_4 PF07975.12 OWF38314.1 - 0.28 11.5 17.4 5 7.5 5.0 4.3 2 1 2 4 4 4 0 TFIIH C1-like domain Pox_A9 PF04835.12 OWF38314.1 - 0.34 11.1 1.0 0.77 9.9 1.0 1.6 1 0 0 1 1 1 0 A9 protein conserved region FYVE PF01363.21 OWF38314.1 - 2.4 8.4 16.9 3.4 7.9 8.4 3.0 2 0 0 2 2 2 0 FYVE zinc finger zf-C2H2_3rep PF18868.1 OWF38314.1 - 2.4 8.8 15.5 2.5 8.8 1.5 4.6 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-RING_7 PF02591.15 OWF38314.1 - 3.5 7.9 8.4 14 5.9 0.2 4.6 5 0 0 5 5 5 0 C4-type zinc ribbon domain zf-C2H2_2 PF12756.7 OWF38314.1 - 6.3 7.2 20.2 11 6.5 1.1 3.8 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Glyco_trans_2_3 PF13632.6 OWF38315.1 - 2.7 7.9 11.1 20 5.0 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferase family group 2 RAI16-like PF10257.9 OWF38317.1 - 7.2e-110 367.2 3.2 7.2e-110 367.2 3.2 1.5 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein Ank_4 PF13637.6 OWF38318.1 - 1.3e-33 114.9 7.0 1.9e-09 37.9 0.0 7.9 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF38318.1 - 3.2e-29 101.3 6.2 2.5e-13 50.4 0.5 4.8 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF38318.1 - 8.9e-21 71.8 7.0 0.0021 18.4 0.0 9.0 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OWF38318.1 - 5.7e-18 64.7 3.8 7.3e-08 32.5 0.2 6.3 5 3 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF38318.1 - 1e-17 63.7 10.7 0.00016 21.9 0.0 7.0 5 1 1 6 6 6 5 Ankyrin repeat Di19_C PF14571.6 OWF38319.1 - 0.0016 19.0 2.5 0.0022 18.5 0.4 2.3 2 0 0 2 2 2 1 Stress-induced protein Di19, C-terminal PilO PF04350.13 OWF38319.1 - 0.17 12.0 2.0 0.18 11.9 0.8 1.7 2 0 0 2 2 2 0 Pilus assembly protein, PilO ZZ PF00569.17 OWF38320.1 - 2.9e-11 43.0 7.0 2.9e-11 43.0 7.0 2.4 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-Di19 PF05605.12 OWF38320.1 - 1.6e-10 41.1 0.1 1.6e-10 41.1 0.1 2.3 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OWF38320.1 - 0.0028 18.0 0.2 0.0028 18.0 0.2 2.8 2 1 0 2 2 1 1 Zinc finger, C2H2 type CpXC PF14353.6 OWF38320.1 - 0.015 15.3 0.6 0.027 14.5 0.6 1.7 1 1 0 1 1 1 0 CpXC protein zf-C2H2_jaz PF12171.8 OWF38320.1 - 0.051 13.9 2.3 0.07 13.4 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MqsA_antitoxin PF15731.5 OWF38320.1 - 0.15 12.2 0.1 0.15 12.2 0.1 1.8 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-H2C2_2 PF13465.6 OWF38320.1 - 0.18 12.3 8.4 1.1 9.8 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 OWF38320.1 - 0.33 11.3 6.0 1.5 9.2 5.5 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OWF38320.1 - 0.35 11.8 0.1 0.35 11.8 0.1 3.4 3 1 0 3 3 2 0 C2H2-type zinc finger zf-RING_5 PF14634.6 OWF38320.1 - 0.42 10.6 11.2 0.33 11.0 0.9 2.9 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF38320.1 - 2 8.3 10.6 5.1 7.0 1.7 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) adh_short_C2 PF13561.6 OWF38321.1 - 1.4e-06 28.0 0.0 1.8e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF38321.1 - 2e-05 24.2 0.3 4.2e-05 23.1 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OWF38321.1 - 0.00032 20.2 0.0 0.0028 17.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UCR_TM PF02921.14 OWF38321.1 - 0.02 15.4 0.3 12 6.5 0.1 2.5 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region DNA_pol_A_exo1 PF01612.20 OWF38322.1 - 2.9e-19 69.4 0.0 7.7e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Sod_Cu PF00080.20 OWF38323.1 - 2.7e-67 225.3 5.9 2.2e-14 53.8 0.0 7.1 6 1 0 6 6 6 6 Copper/zinc superoxide dismutase (SODC) Copper-bind PF00127.20 OWF38323.1 - 0.13 12.7 0.9 6.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family DUF2373 PF10180.9 OWF38324.1 - 0.044 13.6 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) SMC_N PF02463.19 OWF38325.1 - 7.6e-57 192.3 51.1 2.1e-56 190.8 51.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OWF38325.1 - 2.6e-21 76.1 0.0 1e-20 74.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 OWF38325.1 - 3.8e-13 49.9 15.6 3.8e-13 49.9 15.6 5.3 2 2 1 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 OWF38325.1 - 2e-11 44.3 0.1 2.7e-06 27.4 0.0 4.6 4 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system TMF_DNA_bd PF12329.8 OWF38325.1 - 0.0011 18.9 6.7 0.0011 18.9 6.7 10.9 8 4 4 12 12 12 1 TATA element modulatory factor 1 DNA binding AAA_29 PF13555.6 OWF38325.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4227 PF14004.6 OWF38325.1 - 0.025 14.6 0.0 5.3 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) ABC_tran PF00005.27 OWF38325.1 - 0.86 10.1 0.0 0.86 10.1 0.0 7.3 4 2 0 4 4 4 0 ABC transporter DUF2019 PF09450.10 OWF38325.1 - 1.9 8.5 9.2 2.5 8.1 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) FUSC PF04632.12 OWF38325.1 - 6.3 5.2 19.5 0.055 12.0 5.6 3.2 2 1 1 3 3 3 0 Fusaric acid resistance protein family DUF2442 PF10387.9 OWF38327.1 - 1.1e-05 25.6 18.8 9.9 6.6 0.1 7.5 1 1 7 9 9 9 4 Protein of unknown function (DUF2442) DUF2715 PF10895.8 OWF38327.1 - 0.00019 21.1 6.9 4.5 6.9 0.4 5.1 1 1 3 4 4 4 3 Domain of unknown function (DUF2715) EFG_II PF14492.6 OWF38327.1 - 0.0024 17.9 3.5 46 4.2 0.0 6.2 1 1 5 8 8 8 0 Elongation Factor G, domain II Tcp10_C PF07202.13 OWF38327.1 - 0.043 13.8 5.0 17 5.3 0.1 3.5 1 1 3 4 4 4 0 T-complex protein 10 C-terminus Neil1-DNA_bind PF09292.10 OWF38327.1 - 0.5 10.4 37.0 14 5.8 0.6 11.4 2 1 10 14 14 14 0 Endonuclease VIII-like 1, DNA bind LRR_2 PF07723.13 OWF38327.1 - 0.56 11.0 29.4 2.6e+02 2.5 0.0 12.5 3 3 12 16 16 16 0 Leucine Rich Repeat PorA PF11271.8 OWF38327.1 - 3.4 6.9 9.7 24 4.1 0.3 3.7 1 1 2 3 3 3 0 Porin PorA Actino_peptide PF14408.6 OWF38327.1 - 3.9 7.7 7.4 33 4.7 0.1 5.0 4 2 3 7 7 7 0 Ribosomally synthesised peptide in actinomycetes BAR PF03114.18 OWF38328.1 - 1.3e-24 87.2 9.7 2e-24 86.6 9.7 1.2 1 0 0 1 1 1 1 BAR domain Vps5 PF09325.10 OWF38328.1 - 0.0023 17.5 10.4 0.0048 16.5 9.0 2.1 1 1 0 1 1 1 1 Vps5 C terminal like DUF1664 PF07889.12 OWF38328.1 - 0.025 14.6 0.2 0.025 14.6 0.2 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3293 PF11697.8 OWF38328.1 - 0.068 13.7 1.1 0.24 11.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Snapin_Pallidin PF14712.6 OWF38328.1 - 0.16 12.4 0.2 0.16 12.4 0.2 3.9 3 1 1 4 4 4 0 Snapin/Pallidin Arfaptin PF06456.13 OWF38328.1 - 0.43 10.1 9.8 0.45 10.0 8.9 1.5 1 1 0 1 1 1 0 Arfaptin-like domain DUF3340 PF11818.8 OWF38328.1 - 6 7.0 11.5 0.34 11.1 3.8 2.2 2 1 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Cas_Csn2 PF09711.10 OWF38328.1 - 7.9 6.1 10.2 1.9 8.1 0.7 3.1 1 1 1 3 3 3 0 CRISPR-associated protein (Cas_Csn2) eRF1_2 PF03464.15 OWF38329.1 - 1.2e-47 161.6 0.0 1.8e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OWF38329.1 - 7.8e-39 132.7 0.1 1.5e-38 131.8 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OWF38329.1 - 4.5e-20 72.0 0.0 7.4e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 OWF38329.1 - 4.4e-10 40.0 0.0 6.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 OWF38329.1 - 2.2e-08 34.5 0.0 3.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 KTI12 PF08433.10 OWF38330.1 - 6.3e-17 61.9 1.9 3.4e-13 49.7 0.6 2.2 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_18 PF13238.6 OWF38330.1 - 1.5e-06 28.8 2.6 0.00023 21.7 2.6 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF38330.1 - 3.6e-06 27.2 4.6 4e-05 23.8 2.6 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF38330.1 - 0.00098 19.5 0.2 0.0058 17.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OWF38330.1 - 0.0065 16.7 0.1 0.059 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 OWF38330.1 - 0.0094 15.8 0.8 3 7.7 0.1 2.9 2 1 1 3 3 3 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 OWF38330.1 - 0.012 15.6 0.3 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_tran PF00005.27 OWF38330.1 - 0.053 14.0 0.5 0.17 12.4 0.0 2.0 2 1 0 2 2 2 0 ABC transporter GAGBD PF16828.5 OWF38330.1 - 0.065 13.3 1.1 0.18 11.9 1.0 1.8 1 1 1 2 2 2 0 GAG-binding domain on surface antigen Zeta_toxin PF06414.12 OWF38330.1 - 0.098 11.9 0.2 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 OWF38330.1 - 0.11 12.5 0.3 0.39 10.8 0.3 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Acyltransferase PF01553.21 OWF38331.1 - 2.1e-05 24.2 0.2 6.6e-05 22.5 0.2 1.8 1 1 0 1 1 1 1 Acyltransferase CUE PF02845.16 OWF38331.1 - 0.00034 20.2 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 CUE domain Lipoprotein_2 PF00921.17 OWF38331.1 - 0.83 9.2 5.3 0.22 11.1 2.5 1.4 2 0 0 2 2 2 0 Borrelia lipoprotein zf-RRN7 PF11781.8 OWF38332.1 - 4.1e-05 23.2 0.4 8.2e-05 22.2 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 I-set PF07679.16 OWF38333.1 - 2.9e-45 152.3 0.1 5.5e-16 58.4 0.1 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF38333.1 - 1.3e-39 134.6 0.3 1.1e-14 54.8 0.2 4.0 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 OWF38333.1 - 7.1e-29 99.8 0.2 1.1e-10 41.6 0.2 3.7 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF38333.1 - 4.2e-23 81.5 1.4 8e-11 42.1 0.2 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF38333.1 - 1.8e-18 66.7 2.7 1.9e-06 28.0 0.0 4.6 3 2 1 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF38333.1 - 1.6e-09 37.2 2.4 0.1 12.2 0.1 4.3 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 OWF38333.1 - 3.5e-07 30.2 0.3 0.088 12.9 0.0 3.5 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 OWF38333.1 - 3.8e-07 30.3 0.3 0.14 12.4 0.0 4.3 3 1 1 4 4 4 2 T-cell surface glycoprotein CD3 delta chain TMEM154 PF15102.6 OWF38333.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OWF38333.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ODV-E18 PF10717.9 OWF38333.1 - 0.0052 16.6 1.0 0.013 15.3 1.0 1.7 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 OWF38333.1 - 0.14 13.0 0.0 0.34 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Beta-TrCP_D PF12125.8 OWF38334.1 - 0.93 9.4 50.1 0.73 9.8 1.1 9.5 4 3 6 10 10 10 0 D domain of beta-TrCP HTH_OrfB_IS605 PF12323.8 OWF38336.1 - 2e-08 33.6 6.4 4 7.0 0.2 8.4 5 1 5 11 11 11 3 Helix-turn-helix domain SH3_13 PF18335.1 OWF38336.1 - 6.6e-08 32.3 24.1 1.7 8.5 0.2 9.5 1 1 5 6 6 6 4 ATP-dependent RecD-like DNA helicase SH3 domain DUF4314 PF14192.6 OWF38336.1 - 3.9e-05 23.5 24.9 7.9 6.5 0.2 9.2 3 2 5 9 9 9 4 Domain of unknown function (DUF4314) GFO_IDH_MocA_C PF02894.17 OWF38336.1 - 0.19 11.7 5.4 22 5.1 0.0 5.3 3 2 2 6 6 6 0 Oxidoreductase family, C-terminal alpha/beta domain Synuclein PF01387.17 OWF38336.1 - 2 8.7 8.8 6.6 7.0 0.2 3.5 1 1 3 4 4 4 0 Synuclein EndIII_4Fe-2S PF10576.9 OWF38337.1 - 0.19 12.1 37.4 3.4 8.1 1.1 6.3 7 0 0 7 7 7 0 Iron-sulfur binding domain of endonuclease III CIAPIN1 PF05093.13 OWF38337.1 - 2.3 8.8 13.1 7.4 7.1 1.0 3.3 1 1 3 4 4 4 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF902 PF06001.13 OWF38338.1 - 0.0052 17.2 0.0 2.6 8.6 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF902) Sigma70_r4_2 PF08281.12 OWF38338.1 - 0.12 12.0 0.1 19 5.0 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 TTSSLRR PF12468.8 OWF38339.1 - 0.43 10.9 2.0 5.2 7.4 0.1 2.7 2 1 1 3 3 3 0 Type III secretion system leucine rich repeat protein Tcp10_C PF07202.13 OWF38340.1 - 0.00021 21.3 10.0 0.1 12.5 1.2 3.8 1 1 3 4 4 4 4 T-complex protein 10 C-terminus 7tm_1 PF00001.21 OWF38341.1 - 1.4e-60 204.8 12.7 1.9e-60 204.5 12.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF38341.1 - 2.3e-09 37.0 10.6 1.3e-08 34.5 10.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF38341.1 - 8.6e-08 32.2 7.1 5.7e-07 29.6 3.3 2.8 2 1 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF38341.1 - 2.2e-06 27.5 1.9 2.2e-06 27.5 1.9 2.1 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.9 OWF38341.1 - 0.52 9.0 4.8 6.8 5.3 0.3 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 OWF38342.1 - 1.9e-37 129.2 5.4 2.2e-37 129.0 5.4 1.0 1 0 0 1 1 1 1 Tetraspanin family Lectin_C PF00059.21 OWF38343.1 - 7.2e-13 49.2 0.0 7.2e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Lectin C-type domain Peptidase_S64 PF08192.11 OWF38343.1 - 0.18 10.3 6.1 0.25 9.8 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 zf-RING_UBOX PF13445.6 OWF38345.1 - 5e-10 39.2 6.7 5e-10 39.2 6.7 3.6 3 2 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF38345.1 - 4.6e-08 33.1 9.4 4.6e-08 33.1 9.4 4.0 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF38345.1 - 4.9e-08 32.7 8.2 4.9e-08 32.7 8.2 4.3 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF38345.1 - 4.2e-07 30.2 7.1 4.2e-07 30.2 7.1 4.2 4 0 0 4 4 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF38345.1 - 1.1e-06 28.3 5.0 1.1e-06 28.3 5.0 4.8 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF38345.1 - 1.9e-06 27.7 6.6 1.9e-06 27.7 6.6 3.8 4 1 0 4 4 1 1 zinc-RING finger domain zf-B_box PF00643.24 OWF38345.1 - 5.6e-06 26.4 19.4 0.00013 22.0 6.1 4.7 5 1 0 5 5 3 2 B-box zinc finger NHL PF01436.21 OWF38345.1 - 1.6e-05 24.7 5.7 0.005 16.8 0.1 3.6 3 0 0 3 3 3 1 NHL repeat zf-C3HC4_3 PF13920.6 OWF38345.1 - 0.0003 20.6 7.1 0.0003 20.6 7.1 3.8 4 2 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) FlgN PF05130.12 OWF38345.1 - 0.0041 17.6 6.8 0.0073 16.8 6.8 1.4 1 0 0 1 1 1 1 FlgN protein phiKZ_IP PF12699.7 OWF38345.1 - 0.01 15.0 0.8 0.016 14.3 0.8 1.3 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Prok-RING_4 PF14447.6 OWF38345.1 - 0.013 15.4 7.0 0.013 15.4 7.0 3.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Baculo_PEP_C PF04513.12 OWF38345.1 - 0.018 15.1 3.4 0.018 15.1 3.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 OWF38345.1 - 0.18 10.4 3.8 0.28 9.8 3.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A WXG100 PF06013.12 OWF38345.1 - 0.19 12.0 1.2 0.52 10.6 1.2 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Exonuc_VII_L PF02601.15 OWF38345.1 - 0.32 10.5 2.2 0.47 10.0 2.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 OWF38345.1 - 0.52 10.8 7.5 0.94 10.0 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 OWF38345.1 - 3.9 7.9 6.9 25 5.4 0.3 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Halogen_Hydrol PF10112.9 OWF38345.1 - 6.3 6.8 9.0 2.9 7.9 2.5 2.2 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HTH_21 PF13276.6 OWF38346.1 - 0.0018 18.4 0.3 1.9 8.7 0.0 3.3 3 0 0 3 3 3 2 HTH-like domain Terpene_synth_C PF03936.16 OWF38346.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain HTH_Tnp_Tc3_2 PF01498.18 OWF38346.1 - 0.12 12.6 1.4 17 5.8 0.1 2.4 2 0 0 2 2 2 0 Transposase CIDE-N PF02017.15 OWF38347.1 - 4e-19 68.4 0.0 6.8e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 CIDE-N domain zf-C3HC4_3 PF13920.6 OWF38347.1 - 7.4e-05 22.5 0.4 0.00022 21.0 0.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF38347.1 - 0.00011 22.0 0.9 0.0003 20.6 0.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF38347.1 - 0.0033 17.4 4.8 0.0035 17.3 2.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF38347.1 - 0.0055 16.5 0.6 0.0055 16.5 0.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF38347.1 - 0.0071 16.5 1.5 0.02 15.0 1.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF38347.1 - 0.018 15.0 2.3 0.018 15.0 2.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 OWF38347.1 - 0.022 15.1 2.1 0.022 15.1 2.1 2.2 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 OWF38347.1 - 0.033 14.0 0.8 0.078 12.8 0.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF38347.1 - 0.075 12.8 4.5 0.11 12.3 1.4 2.6 2 0 0 2 2 2 0 RING-like zinc finger Fer4_13 PF13370.6 OWF38347.1 - 0.1 13.2 0.2 0.44 11.1 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I C2 PF00168.30 OWF38348.1 - 7.8e-99 324.9 0.0 3.4e-22 78.7 0.0 8.3 7 1 0 7 7 7 7 C2 domain FerB PF08150.12 OWF38348.1 - 8.3e-30 103.2 0.0 1.8e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 OWF38348.1 - 1.3e-25 90.1 0.1 1.3e-25 90.1 0.1 3.4 3 1 1 4 4 4 2 Ferlin C-terminus FerI PF08151.12 OWF38348.1 - 4.3e-18 65.1 0.0 1.1e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain FerA PF08165.11 OWF38348.1 - 8.2e-17 60.9 0.1 2e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 FerA (NUC095) domain PI3K_C2 PF00792.24 OWF38348.1 - 0.013 15.4 1.4 0.17 11.8 0.0 3.2 4 0 0 4 4 4 0 Phosphoinositide 3-kinase C2 dsRBD2 PF17842.1 OWF38348.1 - 0.036 14.3 0.2 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Pex24p PF06398.11 OWF38348.1 - 0.89 8.5 33.9 0.021 13.8 3.1 4.2 5 0 0 5 5 5 0 Integral peroxisomal membrane peroxin Dynactin PF12455.8 OWF38350.1 - 2.1e-78 263.5 15.8 2.1e-78 263.5 15.8 4.1 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 OWF38350.1 - 8.9e-20 70.5 1.1 1.6e-19 69.7 1.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain ATG16 PF08614.11 OWF38350.1 - 0.0092 16.2 22.7 0.0092 16.2 22.7 6.5 4 2 2 6 6 6 4 Autophagy protein 16 (ATG16) Vps51 PF08700.11 OWF38351.1 - 1.6e-24 85.8 3.7 6.3e-24 83.9 3.7 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 OWF38351.1 - 1.6e-21 77.0 4.4 1.6e-21 77.0 4.4 2.6 4 0 0 4 4 4 1 Exocyst complex component Sec5 Dor1 PF04124.12 OWF38351.1 - 6.9e-13 48.0 9.9 6.9e-13 48.0 9.9 2.6 3 0 0 3 3 3 1 Dor1-like family Vps54_N PF10475.9 OWF38351.1 - 4.1e-09 36.1 10.2 1.5e-08 34.3 10.2 1.9 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 OWF38351.1 - 3.2e-05 24.0 0.7 3.2e-05 24.0 0.7 3.1 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 OWF38351.1 - 0.00038 19.5 7.3 0.0011 18.1 7.3 1.7 1 0 0 1 1 1 1 Vps53-like, N-terminal IFT57 PF10498.9 OWF38351.1 - 0.0014 17.7 3.5 0.0045 16.0 3.5 1.8 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 LIF_OSM PF01291.17 OWF38351.1 - 0.0033 17.6 0.3 0.94 9.6 0.2 3.1 2 1 0 2 2 2 1 LIF / OSM family Occludin_ELL PF07303.13 OWF38351.1 - 0.038 14.7 0.5 0.038 14.7 0.5 3.2 2 1 1 3 3 2 0 Occludin homology domain DUF1804 PF08822.11 OWF38351.1 - 0.11 12.5 4.9 5.7 6.9 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) UPF0449 PF15136.6 OWF38351.1 - 0.26 11.8 2.7 1.9 9.0 0.5 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 DASH_Dam1 PF08653.10 OWF38351.1 - 0.56 10.1 2.8 1 9.2 0.2 3.0 3 0 0 3 3 2 0 DASH complex subunit Dam1 Baculo_PEP_C PF04513.12 OWF38351.1 - 0.79 9.8 10.2 0.64 10.1 1.0 3.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hpt PF01627.23 OWF38351.1 - 2.9 8.2 5.6 8.1 6.8 0.1 3.7 3 1 1 4 4 3 0 Hpt domain Sec8_exocyst PF04048.14 OWF38351.1 - 3.2 7.6 9.5 0.11 12.4 1.8 2.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF3385 PF11865.8 OWF38351.1 - 3.3 7.6 5.6 17 5.3 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) COG5 PF10392.9 OWF38351.1 - 3.5 7.8 12.4 0.12 12.5 2.5 3.5 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Snf7 PF03357.21 OWF38352.1 - 1.7e-20 73.4 7.4 2.7e-20 72.6 7.4 1.2 1 0 0 1 1 1 1 Snf7 FYVE PF01363.21 OWF38353.1 - 6.3e-20 71.1 8.8 6.3e-20 71.1 8.8 3.1 2 0 0 2 2 2 1 FYVE zinc finger DUF4698 PF15769.5 OWF38353.1 - 7 5.6 6.9 5.3 6.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) RRM_1 PF00076.22 OWF38355.1 - 1.3e-08 34.5 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tissue_fac PF01108.17 OWF38355.1 - 0.0044 16.9 0.1 0.0075 16.1 0.1 1.5 1 1 0 1 1 1 1 Tissue factor MFS_1 PF07690.16 OWF38356.1 - 3.7e-44 151.1 30.9 5.2e-44 150.6 30.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF38356.1 - 2.9e-12 46.2 5.9 2.9e-12 46.2 5.9 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter DUF1741 PF08427.10 OWF38357.1 - 1.4e-84 283.4 7.0 1.5e-84 283.3 3.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) DALR_1 PF05746.15 OWF38357.1 - 0.016 15.3 1.2 1.7 8.9 0.1 3.4 3 1 0 3 3 3 0 DALR anticodon binding domain CRM1_repeat_2 PF18784.1 OWF38357.1 - 0.083 12.5 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Sel1 PF08238.12 OWF38358.1 - 1.2e-19 70.3 24.9 0.0011 19.6 1.0 7.4 6 2 0 6 6 6 5 Sel1 repeat TPR_6 PF13174.6 OWF38358.1 - 2.1e-07 31.1 9.1 0.51 11.1 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF38358.1 - 0.00013 21.9 14.2 0.027 14.7 0.4 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF38358.1 - 0.0076 16.0 9.2 1.9 8.4 1.7 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF38358.1 - 0.086 12.9 1.8 32 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF38358.1 - 0.096 12.9 17.3 0.35 11.1 2.5 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF38358.1 - 1.8 8.9 8.8 2.2 8.6 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 OWF38358.1 - 7.6 6.3 6.9 38 4.1 0.1 4.1 5 0 0 5 5 5 0 TPR repeat Amino_oxidase PF01593.24 OWF38359.1 - 1.8e-76 258.3 0.0 5.5e-76 256.7 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF38359.1 - 2.4e-11 43.7 0.0 5.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OWF38359.1 - 0.013 14.8 0.1 0.013 14.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF38359.1 - 0.056 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 OWF38359.1 - 0.085 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF3999 PF13163.6 OWF38359.1 - 0.58 9.3 14.4 15 4.7 0.5 4.1 1 1 7 8 8 8 0 Protein of unknown function (DUF3999) Pyr_redox_2 PF07992.14 OWF38359.1 - 0.66 9.2 3.4 0.73 9.0 0.0 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MRP-L27 PF09809.9 OWF38359.1 - 1.1 9.2 40.2 34 4.3 0.5 9.2 9 0 0 9 9 9 0 Mitochondrial ribosomal protein L27 Meckelin PF09773.9 OWF38360.1 - 0.014 13.5 0.2 0.02 13.0 0.2 1.3 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) TROVE PF05731.11 OWF38361.1 - 3.4e-100 336.2 7.7 3.4e-100 336.2 7.7 2.7 2 1 0 2 2 2 1 TROVE domain WD40 PF00400.32 OWF38361.1 - 1.1e-81 266.6 55.2 2.2e-06 28.3 0.2 18.9 18 0 0 18 18 18 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF38361.1 - 3.3e-24 85.0 2.5 6.6e-07 29.5 0.0 10.1 3 3 6 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain DUF4062 PF13271.6 OWF38361.1 - 6.4e-20 71.3 0.0 2.3e-19 69.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) APAF1_C PF17908.1 OWF38361.1 - 5.9e-09 36.0 0.2 2.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 APAF-1 helical domain Ge1_WD40 PF16529.5 OWF38361.1 - 6.7e-09 35.1 0.7 1.2 8.0 0.0 6.8 3 2 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5320 PF17253.2 OWF38361.1 - 4.5e-06 27.7 3.8 0.011 16.8 0.1 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5320) NACHT PF05729.12 OWF38361.1 - 2.5e-05 24.3 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OWF38361.1 - 6e-05 23.3 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain WD40_like PF17005.5 OWF38361.1 - 0.00011 21.6 0.1 3 7.1 0.0 5.4 7 0 0 7 7 7 1 WD40-like domain Ploopntkinase3 PF18751.1 OWF38361.1 - 0.002 18.1 0.2 0.0068 16.3 0.1 2.0 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 OWF38361.1 - 0.0068 16.8 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OWF38361.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OWF38361.1 - 0.15 11.8 0.9 1.2 8.9 0.1 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain FXMRP1_C_core PF12235.8 OWF38361.1 - 0.98 10.1 19.1 1.9 9.2 9.8 2.7 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Cwf_Cwc_15 PF04889.12 OWF38361.1 - 1.6 8.4 9.5 0.029 14.1 2.2 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein API5 PF05918.11 OWF38361.1 - 2.7 6.7 7.2 0.58 8.9 0.3 2.4 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) ALMS_motif PF15309.6 OWF38362.1 - 2.8e-27 95.8 20.0 2.8e-27 95.8 20.0 5.5 6 0 0 6 6 6 1 ALMS motif TPR_1 PF00515.28 OWF38363.1 - 1.4e-30 103.8 29.3 1.7e-06 27.6 0.1 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 OWF38363.1 - 5.1e-29 98.0 24.3 0.0004 20.4 0.0 10.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 OWF38363.1 - 8.4e-26 88.0 30.7 0.00012 21.9 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC8 PF04049.13 OWF38363.1 - 1.1e-25 90.3 12.9 2.5e-24 85.9 8.2 3.1 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 OWF38363.1 - 9.3e-18 63.4 17.7 0.0048 17.6 0.0 9.2 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF38363.1 - 1.4e-11 44.7 20.9 0.12 12.9 0.1 8.0 6 3 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF38363.1 - 1.7e-10 41.3 21.4 0.0002 21.9 0.2 7.3 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF38363.1 - 4.6e-10 39.0 14.6 3e-06 26.8 0.2 5.4 5 1 1 6 6 6 2 TPR repeat TPR_17 PF13431.6 OWF38363.1 - 2.7e-09 36.7 14.1 0.33 11.4 0.1 7.6 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OWF38363.1 - 6e-09 35.3 16.6 0.89 9.7 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF38363.1 - 7.9e-07 29.3 30.5 2.7 8.8 0.1 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF38363.1 - 5.3e-06 26.1 15.7 1.2 9.2 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF38363.1 - 7e-06 26.2 37.1 0.014 15.6 2.2 6.5 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OWF38363.1 - 4e-05 23.7 2.8 0.019 15.1 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF38363.1 - 4.7e-05 23.6 29.6 0.083 13.2 1.2 7.7 4 2 2 8 8 8 5 Tetratricopeptide repeat ChAPs PF09295.10 OWF38363.1 - 0.00092 18.3 2.5 0.11 11.5 0.5 3.1 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) GT-D PF08759.11 OWF38363.1 - 0.083 12.5 3.0 1.1 8.8 0.1 2.9 3 0 0 3 3 3 0 Glycosyltransferase GT-D fold DUF2524 PF10732.9 OWF38363.1 - 0.66 10.3 5.2 0.69 10.3 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) RPN7 PF10602.9 OWF38363.1 - 9 6.0 10.3 1 9.1 0.3 3.9 4 1 0 4 4 4 0 26S proteasome subunit RPN7 Ank_2 PF12796.7 OWF38364.1 - 2.9e-26 91.9 0.5 5.7e-15 55.7 0.0 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38364.1 - 8.2e-24 83.7 1.2 4.3e-08 33.5 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF38364.1 - 7.8e-19 65.8 5.8 7e-05 22.9 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OWF38364.1 - 1.4e-18 66.5 8.0 0.0042 17.5 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OWF38364.1 - 2.6e-18 65.8 2.2 4.6e-06 26.8 0.1 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF38364.1 - 4.8e-09 36.4 0.4 1.8e-08 34.6 0.7 1.9 2 0 0 2 2 2 1 SOCS box BCL9 PF11502.8 OWF38364.1 - 0.066 13.0 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein CH_2 PF06294.11 OWF38365.1 - 1.2e-30 105.5 0.4 2.2e-30 104.6 0.0 1.6 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OWF38365.1 - 1.6e-12 47.1 0.0 3.5e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 OWF38365.1 - 0.0054 16.9 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain SPATA24 PF15175.6 OWF38365.1 - 0.068 13.1 4.7 0.34 10.8 2.1 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Pox_vIL-18BP PF05566.12 OWF38365.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 2 0 0 2 2 2 0 Orthopoxvirus interleukin 18 binding protein Trimer_CC PF08954.11 OWF38365.1 - 1.3 8.6 3.9 20 4.8 0.8 2.6 2 1 0 2 2 2 0 Trimerisation motif PKcGMP_CC PF16808.5 OWF38365.1 - 3.3 7.6 8.4 4.8 7.1 3.2 2.9 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MMR_HSR1 PF01926.23 OWF38366.1 - 9.1e-10 38.6 0.0 9.6e-09 35.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF38366.1 - 0.00093 18.8 0.1 0.0038 16.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OWF38366.1 - 0.00095 19.3 0.1 0.019 15.1 0.0 2.7 3 0 0 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 OWF38366.1 - 0.016 15.1 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 OWF38366.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OWF38366.1 - 0.68 10.4 3.5 5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Slu7 PF11708.8 OWF38367.1 - 2.1e-104 349.1 16.1 2.1e-104 349.1 16.1 2.1 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 OWF38367.1 - 0.027 14.2 0.4 0.056 13.2 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Pro_isomerase PF00160.21 OWF38368.1 - 3.3e-46 157.4 0.1 3.7e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RhoGEF PF00621.20 OWF38369.1 - 5.2e-30 105.0 2.1 7.3e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain TIP_N PF12457.8 OWF38369.1 - 0.0085 16.4 0.4 0.043 14.2 0.4 2.2 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal CheY-binding PF09078.11 OWF38369.1 - 0.062 13.4 0.6 0.38 10.9 0.1 2.5 1 1 1 2 2 2 0 CheY binding SKA2 PF16740.5 OWF38369.1 - 0.068 13.0 5.2 0.28 11.0 5.2 2.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 OWF38369.1 - 0.12 11.2 12.3 0.025 13.5 7.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 OWF38369.1 - 0.18 12.5 9.4 0.31 11.7 3.8 2.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 OWF38369.1 - 6.1 6.9 9.5 12 5.9 7.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) 7tm_1 PF00001.21 OWF38370.1 - 4.2e-19 68.9 19.3 5.7e-19 68.5 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Fuseless PF15993.5 OWF38371.1 - 8.2e-79 264.9 26.8 9.9e-79 264.6 26.8 1.1 1 0 0 1 1 1 1 Fuseless zf-C3HC4 PF00097.25 OWF38372.1 - 3.8e-10 39.5 5.1 3.8e-10 39.5 5.1 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF38372.1 - 1.1e-09 38.2 6.2 3e-09 36.8 6.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF38372.1 - 1.2e-09 37.8 6.9 1.2e-09 37.8 6.9 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF38372.1 - 1.3e-08 34.6 4.0 1.3e-08 34.6 4.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF38372.1 - 2.2e-08 34.1 7.6 2.2e-08 34.1 7.6 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF38372.1 - 3.5e-08 33.2 6.0 3.5e-08 33.2 6.0 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF38372.1 - 5.5e-07 29.8 7.5 5.5e-07 29.8 7.5 2.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF38372.1 - 1.4e-06 28.1 4.3 1.4e-06 28.1 4.3 2.5 3 0 0 3 3 2 1 zinc-RING finger domain U-box PF04564.15 OWF38372.1 - 1.6e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain Sina PF03145.16 OWF38372.1 - 0.00053 20.0 2.1 0.0012 18.8 1.5 1.9 1 1 0 1 1 1 1 Seven in absentia protein family N2227 PF07942.12 OWF38372.1 - 0.0025 17.1 0.4 0.2 10.8 0.1 2.3 2 0 0 2 2 2 1 N2227-like protein zf-rbx1 PF12678.7 OWF38372.1 - 0.003 17.8 6.8 0.003 17.8 6.8 2.7 2 2 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF38372.1 - 0.0034 17.5 4.3 0.0034 17.5 4.3 2.2 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-ACC PF17848.1 OWF38372.1 - 0.0073 16.4 3.4 0.048 13.7 0.2 3.1 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf-ANAPC11 PF12861.7 OWF38372.1 - 0.0085 16.1 3.1 0.042 13.9 3.1 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OWF38372.1 - 0.0099 15.7 4.5 0.0099 15.7 4.5 2.3 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain ADIP PF11559.8 OWF38372.1 - 0.017 15.2 4.4 0.033 14.3 4.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-TRAF PF02176.18 OWF38372.1 - 0.033 14.9 6.8 0.078 13.7 0.8 2.6 1 1 1 2 2 2 0 TRAF-type zinc finger CENP-F_leu_zip PF10473.9 OWF38372.1 - 0.033 14.2 3.2 0.056 13.5 3.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 OWF38372.1 - 0.067 13.8 0.5 0.14 12.8 0.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA zf_UBZ PF18439.1 OWF38372.1 - 0.095 12.3 3.8 6.6 6.4 0.3 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TPR_MLP1_2 PF07926.12 OWF38372.1 - 0.098 12.7 4.8 0.22 11.6 4.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TF_Zn_Ribbon PF08271.12 OWF38372.1 - 0.14 11.6 0.1 0.14 11.6 0.1 3.4 4 0 0 4 4 3 0 TFIIB zinc-binding zf-ZPR1 PF03367.13 OWF38372.1 - 0.15 11.9 5.0 0.083 12.7 1.5 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain zf-Nse PF11789.8 OWF38372.1 - 0.27 11.1 2.7 0.72 9.7 2.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 OWF38372.1 - 0.54 10.2 16.6 2.3 8.2 0.7 4.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 DZR PF12773.7 OWF38372.1 - 0.56 10.3 11.8 36 4.5 11.1 3.2 1 1 0 1 1 1 0 Double zinc ribbon Cnn_1N PF07989.11 OWF38372.1 - 0.72 10.1 5.8 1.3 9.3 5.3 1.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Cep57_CLD_2 PF14197.6 OWF38372.1 - 1.1 9.4 10.0 9.4 6.4 0.1 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 zf_C2HC_14 PF18574.1 OWF38372.1 - 1.8 8.4 10.5 9.3 6.1 0.3 3.6 3 0 0 3 3 3 0 C2HC Zing finger domain zf-ribbon_3 PF13248.6 OWF38372.1 - 3 7.4 7.4 14 5.2 0.1 3.9 3 0 0 3 3 3 0 zinc-ribbon domain RNase_H2_suC PF08615.11 OWF38373.1 - 2e-19 70.2 0.3 3.5e-17 62.9 0.3 2.1 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LURAP PF14854.6 OWF38374.1 - 4.8e-07 29.7 2.8 4.8e-07 29.7 2.8 2.9 1 1 1 2 2 2 1 Leucine rich adaptor protein DUF4530 PF15039.6 OWF38374.1 - 0.05 13.8 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) PA28_beta PF02252.18 OWF38375.1 - 0.073 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit SANTA PF09133.10 OWF38376.1 - 3e-23 82.1 0.3 9.6e-23 80.5 0.3 2.0 1 0 0 1 1 1 1 SANTA (SANT Associated) Glyoxalase PF00903.25 OWF38376.1 - 1.3e-20 73.9 0.0 3.2e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OWF38376.1 - 1.7e-07 31.5 0.0 9.5e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OWF38376.1 - 0.0011 19.7 0.0 0.0033 18.2 0.0 1.9 1 0 0 1 1 1 1 Glyoxalase-like domain Myb_DNA-binding PF00249.31 OWF38376.1 - 0.014 15.6 0.9 0.042 14.1 0.5 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Glyoxalase_2 PF12681.7 OWF38376.1 - 0.088 12.7 0.1 2.5 8.0 0.0 3.0 2 0 0 2 2 2 0 Glyoxalase-like domain Methyltransf_11 PF08241.12 OWF38377.1 - 5.9e-17 62.1 0.0 1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF38377.1 - 1.5e-14 54.2 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF38377.1 - 2.3e-13 50.6 0.0 4.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF38377.1 - 4.7e-09 36.9 0.0 9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF38377.1 - 1.3e-07 31.5 0.0 3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF38377.1 - 2.1e-05 24.0 0.0 4.4e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 OWF38377.1 - 9.8e-05 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_29 PF03141.16 OWF38377.1 - 0.00057 18.6 0.0 0.00083 18.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 OWF38377.1 - 0.00075 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 OWF38377.1 - 0.0056 16.6 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_7 PF03492.15 OWF38377.1 - 0.053 12.7 0.0 0.78 8.9 0.0 2.2 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase Methyltransf_32 PF13679.6 OWF38377.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 OWF38378.1 - 1.2e-11 44.1 32.2 8.4e-11 41.4 13.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF38378.1 - 0.0025 16.7 5.5 0.0025 16.7 5.5 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Med9 PF07544.13 OWF38379.1 - 0.78 9.9 6.3 0.19 11.8 2.4 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Kelch_1 PF01344.25 OWF38380.1 - 1.7e-44 149.1 9.1 7.6e-10 38.2 0.0 5.8 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 OWF38380.1 - 3.6e-35 119.1 4.9 1.6e-06 28.2 0.0 5.5 4 1 1 5 5 5 5 Kelch motif BTB PF00651.31 OWF38380.1 - 5.5e-27 94.2 0.1 4e-26 91.4 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 OWF38380.1 - 4.7e-26 90.5 4.0 7.3e-08 32.5 0.2 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF38380.1 - 5.4e-25 87.1 0.5 5.2e-06 26.4 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF38380.1 - 8e-18 63.7 2.9 4.9e-05 23.1 0.0 6.8 6 1 0 6 6 6 4 Kelch motif BACK PF07707.15 OWF38380.1 - 2.6e-14 53.2 0.6 5.1e-14 52.2 0.6 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 OWF38380.1 - 2.3e-11 43.4 11.5 0.039 13.9 0.4 5.2 5 0 0 5 5 5 4 Kelch motif ABC_membrane PF00664.23 OWF38381.1 - 2.2e-64 217.8 8.4 2.9e-64 217.4 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OWF38381.1 - 4.5e-32 111.4 0.0 9.3e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF38381.1 - 1.5e-05 24.5 2.3 0.0015 18.0 2.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OWF38381.1 - 0.00055 18.9 0.1 0.031 13.1 0.1 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class PYC_OADA PF02436.18 OWF38381.1 - 0.0031 17.3 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 Conserved carboxylase domain Zeta_toxin PF06414.12 OWF38381.1 - 0.0038 16.5 0.0 0.0085 15.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 OWF38381.1 - 0.0062 16.3 0.3 0.015 15.0 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OWF38381.1 - 0.0062 16.1 0.3 0.019 14.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF38381.1 - 0.015 15.6 0.6 0.13 12.6 0.5 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OWF38381.1 - 0.022 15.1 0.3 0.057 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 OWF38381.1 - 0.037 14.2 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OWF38381.1 - 0.13 12.1 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2294 PF10057.9 OWF38381.1 - 0.21 11.7 1.2 0.83 9.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) ADD_DNMT3 PF17980.1 OWF38382.1 - 2e-14 53.3 2.8 2e-14 53.3 2.8 2.8 3 0 0 3 3 3 1 Cysteine rich ADD domain in DNMT3 PWWP PF00855.17 OWF38382.1 - 4.9e-09 36.5 0.3 4.9e-09 36.5 0.3 2.8 3 0 0 3 3 3 1 PWWP domain Pecanex_C PF05041.15 OWF38383.1 - 5.7e-116 385.9 0.0 9.1e-116 385.3 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) SNN_transmemb PF09049.10 OWF38383.1 - 0.061 13.3 2.2 0.17 11.9 2.2 1.8 1 0 0 1 1 1 0 Stannin transmembrane HAD_2 PF13419.6 OWF38384.1 - 4.9e-07 30.0 0.1 6.9e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OWF38384.1 - 8.9e-06 26.1 0.0 1.2e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 OWF38384.1 - 0.5 10.3 8.9 0.52 10.3 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.11 OWF38385.1 - 0.0075 16.5 25.7 0.0075 16.5 25.7 10.3 2 2 7 9 9 9 3 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OWF38385.1 - 0.014 15.5 3.8 0.014 15.5 3.8 12.8 3 3 10 13 13 13 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 OWF38385.1 - 0.025 14.7 1.2 0.025 14.7 1.2 16.4 9 4 9 18 18 18 0 bZIP transcription factor bZIP_2 PF07716.15 OWF38385.1 - 0.057 13.5 0.2 0.057 13.5 0.2 17.0 15 3 3 19 19 19 0 Basic region leucine zipper DUF2232 PF09991.9 OWF38385.1 - 0.43 9.7 1.9 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Big_3_2 PF12245.8 OWF38385.1 - 0.92 9.8 7.1 0.85 9.9 0.4 3.6 1 1 1 2 2 2 0 Bacterial Ig-like domain RNA_POL_M_15KD PF02150.16 OWF38386.1 - 8e-15 54.4 3.9 8e-15 54.4 3.9 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 OWF38386.1 - 4.5e-11 42.4 2.8 4.5e-11 42.4 2.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 OWF38386.1 - 4.1e-05 24.0 8.0 0.0054 17.2 0.5 2.1 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain CpXC PF14353.6 OWF38386.1 - 0.0042 17.1 6.6 0.44 10.6 0.3 2.3 2 1 0 2 2 2 2 CpXC protein DZR PF12773.7 OWF38386.1 - 0.0076 16.3 1.7 0.0076 16.3 1.7 2.4 2 1 1 3 3 3 1 Double zinc ribbon C1_1 PF00130.22 OWF38386.1 - 0.013 15.4 1.0 0.013 15.4 1.0 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ogr_Delta PF04606.12 OWF38386.1 - 0.045 13.7 4.7 0.045 13.7 4.7 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF3716 PF12511.8 OWF38386.1 - 0.046 13.8 5.1 1.1 9.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Elf1 PF05129.13 OWF38386.1 - 0.23 11.5 8.5 2.5 8.2 0.5 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf_C2H2_10 PF18414.1 OWF38386.1 - 0.32 10.6 4.5 0.43 10.2 1.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger zinc_ribbon_9 PF14369.6 OWF38386.1 - 0.49 10.7 6.8 7.9 6.8 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 OWF38386.1 - 0.9 9.1 7.3 0.84 9.2 0.3 3.4 3 1 0 3 3 3 0 TFIIB zinc-binding zf-C4_Topoisom PF01396.19 OWF38386.1 - 3.6 7.5 10.4 1.4 8.8 1.1 2.6 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_10 PF10058.9 OWF38386.1 - 4.1 7.2 13.0 1.5 8.6 2.8 2.7 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ACC PF17848.1 OWF38386.1 - 4.7 7.4 16.2 7.2 6.8 3.8 3.7 3 1 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Zn_Tnp_IS1595 PF12760.7 OWF38386.1 - 5.1 7.2 13.2 0.26 11.3 1.7 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Sacchrp_dh_NADP PF03435.18 OWF38387.1 - 5.6e-20 71.9 0.0 8.1e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 OWF38387.1 - 0.0099 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OWF38387.1 - 0.024 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GSDH PF07995.11 OWF38388.1 - 6.8e-24 84.8 0.0 1e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Fibrinogen_C PF00147.18 OWF38388.1 - 0.011 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain FHA PF00498.26 OWF38390.1 - 8.4e-06 26.1 0.1 1.9e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 OWF38390.1 - 0.0026 18.1 0.2 0.0076 16.7 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B UBZ_FAAP20 PF15750.5 OWF38390.1 - 0.016 15.1 0.9 0.034 14.1 0.2 1.8 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger C2-C2_1 PF11618.8 OWF38390.1 - 0.018 15.1 0.3 0.52 10.4 0.0 2.7 3 0 0 3 3 3 0 First C2 domain of RPGR-interacting protein 1 NPV_P10 PF05531.12 OWF38390.1 - 0.12 12.8 1.9 0.27 11.7 1.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prp19 PF08606.11 OWF38390.1 - 0.13 12.3 0.8 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like Leu_zip PF15294.6 OWF38390.1 - 0.16 11.5 4.7 0.35 10.3 4.7 1.5 1 1 0 1 1 1 0 Leucine zipper SIKE PF05769.11 OWF38390.1 - 0.22 11.4 3.0 0.54 10.2 1.5 2.2 1 1 1 2 2 2 0 SIKE family Cnn_1N PF07989.11 OWF38390.1 - 0.59 10.3 5.5 5.8 7.2 5.5 2.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 OWF38390.1 - 0.99 9.6 3.6 1.1 9.4 1.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor Kinesin PF00225.23 OWF38391.1 - 1.6e-79 267.2 0.8 2.1e-79 266.9 0.8 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF38391.1 - 4.3e-23 81.9 0.1 7.2e-22 77.9 0.1 2.2 1 1 0 1 1 1 1 Microtubule binding Dmrt1 PF12374.8 OWF38391.1 - 0.2 12.1 1.2 1.8 9.1 0.0 2.6 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 AAA PF00004.29 OWF38392.1 - 2.7e-42 144.3 0.0 6.3e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OWF38392.1 - 1.7e-10 40.7 0.2 3.2e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OWF38392.1 - 2e-09 37.1 0.2 3.8e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OWF38392.1 - 9.6e-07 29.1 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OWF38392.1 - 3.9e-06 27.2 0.1 0.0019 18.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OWF38392.1 - 3.3e-05 23.2 0.0 5.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OWF38392.1 - 7.3e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OWF38392.1 - 9e-05 22.9 0.1 0.0033 17.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OWF38392.1 - 0.00014 21.8 0.2 0.00069 19.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OWF38392.1 - 0.0013 19.2 0.1 0.0056 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OWF38392.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 OWF38392.1 - 0.0032 17.6 0.0 0.0084 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OWF38392.1 - 0.0034 17.0 0.5 0.36 10.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 OWF38392.1 - 0.0044 16.6 0.2 0.014 15.0 0.1 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 OWF38392.1 - 0.0056 16.9 0.3 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OWF38392.1 - 0.0058 16.7 0.0 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OWF38392.1 - 0.0063 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ATPase PF06745.13 OWF38392.1 - 0.0078 15.6 0.2 0.25 10.7 0.0 2.5 2 1 1 3 3 3 1 KaiC AAA_11 PF13086.6 OWF38392.1 - 0.013 15.4 0.6 1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OWF38392.1 - 0.016 14.7 0.0 0.083 12.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 OWF38392.1 - 0.016 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OWF38392.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OWF38392.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 OWF38392.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OWF38392.1 - 0.036 13.8 0.8 0.1 12.3 0.2 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OWF38392.1 - 0.058 13.9 0.1 0.33 11.5 0.1 2.4 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 OWF38392.1 - 0.059 13.1 0.2 0.15 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OWF38392.1 - 0.087 12.7 0.0 0.61 10.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.22 OWF38392.1 - 0.1 11.7 0.1 0.53 9.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 OWF38392.1 - 0.1 11.6 0.1 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 OWF38392.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 OWF38392.1 - 0.14 12.1 0.9 1.5 8.7 0.0 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea MEA1 PF06910.11 OWF38393.1 - 3.2e-14 53.7 10.7 3.2e-14 53.7 10.7 2.6 2 1 0 2 2 2 1 Male enhanced antigen 1 (MEA1) 2OG-FeII_Oxy_3 PF13640.6 OWF38394.1 - 4.8e-22 78.7 0.0 1.7e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OWF38394.1 - 5.1e-14 52.7 0.2 1.4e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 OWF38394.1 - 2.1e-10 40.5 17.0 5.3e-10 39.2 17.0 1.7 1 0 0 1 1 1 1 MYND finger Stealth_CR1 PF17101.5 OWF38394.1 - 0.044 13.5 0.2 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 zf-Mss51 PF13824.6 OWF38394.1 - 7 6.8 10.8 18 5.5 10.8 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Mab-21 PF03281.14 OWF38395.1 - 2.1e-51 175.0 0.0 3.3e-51 174.3 0.0 1.3 1 1 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.14 OWF38396.1 - 4.8e-35 121.3 1.0 5.8e-35 121.0 1.0 1.0 1 0 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.14 OWF38397.1 - 1.5e-49 168.9 0.0 2e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.14 OWF38398.1 - 2.3e-33 115.8 3.1 2.3e-19 69.8 0.6 2.0 1 1 1 2 2 2 2 Mab-21 protein Mab-21 PF03281.14 OWF38399.1 - 1.5e-27 96.7 0.0 2.6e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Mab-21 protein DHHC PF01529.20 OWF38400.1 - 1.6e-26 93.0 24.6 2.4e-26 92.4 14.1 2.4 2 0 0 2 2 2 2 DHHC palmitoyltransferase Zip PF02535.22 OWF38400.1 - 0.0045 16.2 0.1 0.0096 15.2 0.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter ChaC PF04752.12 OWF38401.1 - 5.1e-59 199.3 0.0 5.8e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 OWF38401.1 - 0.006 17.2 0.1 0.0085 16.7 0.1 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF1246 PF06849.12 OWF38402.1 - 0.25 11.3 0.8 7.5 6.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1246) DUF89 PF01937.19 OWF38403.1 - 3.8e-114 381.3 0.0 4.3e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 MOZ_SAS PF01853.18 OWF38405.1 - 1.7e-85 285.2 0.6 2.8e-85 284.5 0.6 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OWF38405.1 - 2.4e-23 81.5 1.3 2.4e-23 81.5 1.3 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 OWF38405.1 - 6.6e-17 61.1 0.1 1.7e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OWF38405.1 - 0.00029 21.2 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF38405.1 - 0.0019 18.5 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ORC6 PF05460.13 OWF38405.1 - 0.047 13.0 0.4 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RNA_pol_Rpc34 PF05158.12 OWF38406.1 - 6.6e-94 315.0 1.3 1e-93 314.4 1.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 OWF38406.1 - 0.0011 19.6 0.1 0.3 11.7 0.0 3.0 3 0 0 3 3 3 1 Replication protein A C terminal CDC24_OB1 PF17246.2 OWF38406.1 - 0.004 17.3 0.1 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 1 Pullulanase_Ins PF18494.1 OWF38406.1 - 0.022 15.2 0.1 0.09 13.3 0.0 2.1 2 0 0 2 2 2 0 Pullulanase Ins domain TrmB PF01978.19 OWF38406.1 - 0.03 14.2 2.7 0.5 10.3 0.2 3.2 3 1 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.6 OWF38406.1 - 0.19 11.7 2.5 0.45 10.5 2.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix Mito_carr PF00153.27 OWF38407.1 - 2.8e-55 184.2 0.5 5.5e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RBB1NT PF08169.11 OWF38408.1 - 4.7e-26 90.8 0.2 7.6e-25 86.9 0.2 3.3 1 0 0 1 1 1 1 RBB1NT (NUC162) domain ARID PF01388.21 OWF38408.1 - 2.8e-23 82.4 0.8 7.6e-23 81.0 0.1 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 OWF38408.1 - 1.2e-11 44.3 0.5 1.2e-11 44.3 0.5 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 OWF38408.1 - 0.013 15.2 0.3 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 OWF38408.1 - 0.07 13.0 0.2 2.5 8.0 0.0 2.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain RRM_1 PF00076.22 OWF38409.1 - 1.1e-30 105.2 0.0 6.1e-16 58.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF38409.1 - 3.4e-06 27.1 0.1 0.086 13.0 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OWF38409.1 - 2.7e-05 24.1 0.0 0.061 13.3 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 OWF38409.1 - 0.00093 19.1 1.0 2 8.4 0.4 3.5 2 2 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 OWF38409.1 - 0.0037 17.1 0.0 0.14 12.0 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 OWF38409.1 - 0.02 14.7 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif Pkinase PF00069.25 OWF38410.1 - 3.2e-68 230.0 0.0 4e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38410.1 - 1.3e-44 152.4 0.0 1.9e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OWF38410.1 - 1.8e-12 47.4 0.1 4.1e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 OWF38410.1 - 1.3e-05 24.7 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF38410.1 - 0.00011 21.1 0.0 0.00019 20.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF38410.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 OWF38411.1 - 1.8e-05 24.5 0.0 0.00056 19.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF38411.1 - 0.0023 17.5 0.0 0.0059 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.19 OWF38411.1 - 0.3 8.9 10.1 0.43 8.4 10.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 OWF38411.1 - 1 8.1 15.7 0.032 13.1 9.7 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain SIR2 PF02146.17 OWF38412.1 - 7.6e-56 188.8 0.0 1.1e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family SIR2 PF02146.17 OWF38413.1 - 1.3e-54 184.8 0.0 1.8e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family AAA PF00004.29 OWF38414.1 - 1.6e-68 229.2 0.0 9.7e-46 155.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF38414.1 - 1.6e-11 44.9 2.1 0.00021 21.7 0.0 3.9 3 1 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 OWF38414.1 - 3.9e-10 39.9 0.0 0.00014 21.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF38414.1 - 6.9e-10 39.3 0.2 0.0013 19.0 0.0 3.6 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.12 OWF38414.1 - 8.3e-10 38.6 0.0 0.00048 19.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OWF38414.1 - 4.2e-08 33.8 0.0 0.0054 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OWF38414.1 - 6.1e-08 33.0 0.0 0.024 15.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 OWF38414.1 - 9.4e-08 32.3 0.0 0.017 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OWF38414.1 - 4.6e-07 29.7 0.0 0.033 13.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 OWF38414.1 - 1e-06 28.2 0.0 0.022 14.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_28 PF13521.6 OWF38414.1 - 1.1e-06 29.1 0.4 0.087 13.1 0.1 3.4 2 1 1 3 3 3 2 AAA domain TsaE PF02367.17 OWF38414.1 - 1.2e-06 28.5 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 OWF38414.1 - 1.8e-06 27.7 0.3 0.0011 18.7 0.1 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_25 PF13481.6 OWF38414.1 - 2.3e-06 27.4 0.1 0.036 13.6 0.1 2.8 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OWF38414.1 - 9.2e-06 25.2 0.3 0.025 13.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OWF38414.1 - 1.2e-05 24.9 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OWF38414.1 - 3.3e-05 23.7 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OWF38414.1 - 4.1e-05 23.8 0.0 0.26 11.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OWF38414.1 - 4.9e-05 23.4 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OWF38414.1 - 0.0001 22.3 0.0 0.75 9.7 0.0 3.1 3 0 0 3 3 3 2 NACHT domain PhoH PF02562.16 OWF38414.1 - 0.0001 21.8 0.1 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Rad17 PF03215.15 OWF38414.1 - 0.00013 21.9 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 OWF38414.1 - 0.0002 21.9 0.0 0.085 13.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 OWF38414.1 - 0.00025 21.4 0.0 0.72 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 OWF38414.1 - 0.00034 20.4 0.0 0.98 9.1 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin PF02224.18 OWF38414.1 - 0.00044 20.0 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase NB-ARC PF00931.22 OWF38414.1 - 0.00077 18.7 0.0 1.2 8.2 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_17 PF13207.6 OWF38414.1 - 0.00096 19.6 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OWF38414.1 - 0.0012 18.6 0.1 0.049 13.4 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 OWF38414.1 - 0.0017 18.3 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OWF38414.1 - 0.002 18.1 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 OWF38414.1 - 0.0024 17.6 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OWF38414.1 - 0.0026 17.6 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OWF38414.1 - 0.0027 16.9 0.0 0.098 11.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Vps4_C PF09336.10 OWF38414.1 - 0.0029 17.6 0.0 0.0068 16.4 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain ATPase PF06745.13 OWF38414.1 - 0.0042 16.5 0.1 0.42 9.9 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_29 PF13555.6 OWF38414.1 - 0.0052 16.5 0.1 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_3 PF07726.11 OWF38414.1 - 0.0057 16.5 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 OWF38414.1 - 0.0059 16.7 0.0 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OWF38414.1 - 0.0072 15.4 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 RsgA_GTPase PF03193.16 OWF38414.1 - 0.0074 16.2 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Cytidylate_kin2 PF13189.6 OWF38414.1 - 0.0079 16.3 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family TniB PF05621.11 OWF38414.1 - 0.014 14.8 0.0 3.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein APS_kinase PF01583.20 OWF38414.1 - 0.015 15.2 0.4 0.14 12.0 0.0 2.5 3 0 0 3 3 2 0 Adenylylsulphate kinase SRP54 PF00448.22 OWF38414.1 - 0.029 14.0 0.2 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OWF38414.1 - 0.032 13.5 0.0 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SKI PF01202.22 OWF38414.1 - 0.035 14.2 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase T2SSE PF00437.20 OWF38414.1 - 0.052 12.6 0.0 6.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 OWF38414.1 - 0.075 13.0 0.0 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.25 OWF38414.1 - 0.083 12.5 0.0 6.8 6.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.21 OWF38414.1 - 0.088 12.5 0.1 27 4.4 0.0 3.5 4 0 0 4 4 3 0 Guanylate kinase DUF2075 PF09848.9 OWF38414.1 - 0.2 10.8 0.0 0.45 9.7 0.0 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) Gcd10p PF04189.13 OWF38416.1 - 2.1e-66 224.1 0.2 2.1e-66 224.1 0.2 2.1 2 0 0 2 2 2 1 Gcd10p family START PF01852.19 OWF38417.1 - 1.3e-10 41.0 0.0 4e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.9 OWF38417.1 - 0.00042 20.6 0.0 0.032 14.5 0.0 2.4 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OWF38417.1 - 0.0005 20.3 0.3 0.0053 17.0 0.1 2.4 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Put_DNA-bind_N PF06971.13 OWF38418.1 - 0.0029 17.6 2.4 27 4.9 0.0 5.3 1 1 4 7 7 7 1 Putative DNA-binding protein N-terminus UPF0227 PF05728.12 OWF38418.1 - 0.31 11.0 3.5 12 5.7 0.1 3.2 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0227) PetL PF05115.14 OWF38418.1 - 4.3 7.4 25.4 10 6.2 0.1 7.4 3 2 7 10 10 10 0 Cytochrome B6-F complex subunit VI (PetL) YSIRK_signal PF04650.17 OWF38418.1 - 5.9 6.8 52.6 32 4.5 0.1 12.2 14 0 0 14 14 14 0 YSIRK type signal peptide zf-RING_2 PF13639.6 OWF38419.1 - 1.1e-07 32.0 10.8 2.1e-07 31.2 10.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OWF38419.1 - 5e-07 29.5 11.0 8.2e-07 28.8 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF38419.1 - 1e-06 28.7 1.9 1e-06 28.7 1.9 2.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF38419.1 - 1.1e-06 28.3 11.2 3.8e-06 26.6 11.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF38419.1 - 2e-06 27.7 12.7 6.5e-06 26.0 12.9 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF38419.1 - 2.8e-05 23.9 12.1 6.4e-05 22.7 12.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF38419.1 - 0.0004 20.2 13.8 0.025 14.5 14.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF38419.1 - 0.0014 18.3 8.0 0.0014 18.3 8.0 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OWF38419.1 - 0.0024 18.1 11.1 0.0095 16.2 11.1 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-UDP PF14569.6 OWF38419.1 - 0.029 14.5 4.2 0.059 13.5 4.2 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger T3SS_NleG PF06416.12 OWF38419.1 - 0.053 13.4 1.1 0.31 10.9 0.6 2.0 2 0 0 2 2 2 0 Effector protein NleG zinc-ribbons_6 PF07191.12 OWF38419.1 - 0.11 12.5 8.4 0.2 11.6 8.4 1.4 1 1 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 OWF38419.1 - 0.32 11.2 7.3 1.4 9.1 4.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4_4 PF15227.6 OWF38419.1 - 0.77 10.0 14.0 1 9.6 8.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OWF38419.1 - 0.91 9.6 5.8 1.7 8.7 5.8 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pentapeptide_4 PF13599.6 OWF38420.1 - 3.4e-11 43.1 11.4 0.32 11.2 0.1 5.9 1 1 4 6 6 6 6 Pentapeptide repeats (9 copies) MbtH PF03621.13 OWF38420.1 - 1.9e-08 33.6 12.8 30 4.1 0.0 12.4 1 1 22 23 23 23 2 MbtH-like protein NAD_binding_7 PF13241.6 OWF38420.1 - 0.88 10.0 16.0 1.8e+04 -7.9 16.0 5.4 1 1 0 1 1 1 0 Putative NAD(P)-binding FAM193_C PF15914.5 OWF38422.1 - 1.2e-17 63.3 1.9 1.2e-17 63.3 1.9 2.9 2 1 0 2 2 2 1 FAM193 family C-terminal RAWUL PF16207.5 OWF38424.1 - 9e-12 45.5 0.0 2.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 OWF38424.1 - 2e-10 40.3 11.2 4.5e-10 39.2 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF38424.1 - 6.1e-09 35.6 11.7 6.1e-09 35.6 11.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF38424.1 - 1.1e-05 25.3 7.3 3.4e-05 23.8 7.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF38424.1 - 1.2e-05 25.5 9.2 1.2e-05 25.5 9.2 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF38424.1 - 3.8e-05 23.5 8.7 8.2e-05 22.4 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF38424.1 - 0.00019 21.3 12.9 0.00058 19.8 12.0 2.2 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF38424.1 - 0.00047 19.9 8.1 0.0038 17.1 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OWF38424.1 - 0.0016 18.2 4.7 0.0034 17.1 4.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 OWF38424.1 - 0.0062 16.6 8.9 0.0062 16.6 8.9 2.0 2 1 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OWF38424.1 - 0.0064 16.6 10.0 0.016 15.4 10.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OWF38424.1 - 0.01 16.1 7.0 0.024 14.9 7.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain TackOD1 PF18551.1 OWF38424.1 - 0.012 15.3 10.2 0.015 15.0 4.6 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF3337 PF11816.8 OWF38424.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF1272 PF06906.11 OWF38424.1 - 0.12 12.5 6.1 0.32 11.1 6.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) YhfH PF14149.6 OWF38424.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.6 OWF38424.1 - 0.18 11.3 0.3 0.18 11.3 0.3 2.5 3 0 0 3 3 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 OWF38424.1 - 0.49 10.4 8.1 1.4 9.0 8.1 1.8 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 OWF38424.1 - 1.3 9.1 7.9 0.31 11.1 2.6 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.6 OWF38424.1 - 4.8 7.1 7.5 0.99 9.3 4.0 1.6 2 0 0 2 2 1 0 zf-RING of BARD1-type protein RAWUL PF16207.5 OWF38425.1 - 3.5e-14 53.2 0.8 8.1e-14 52.1 0.3 1.9 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 OWF38425.1 - 1e-10 41.2 9.5 1e-10 41.2 9.5 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF38425.1 - 1.6e-08 34.2 10.4 1.6e-08 34.2 10.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF38425.1 - 5.6e-05 23.4 12.3 5.6e-05 23.4 12.3 2.0 2 1 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF38425.1 - 0.00022 21.1 6.3 0.00022 21.1 6.3 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF38425.1 - 0.00036 20.3 11.3 0.00036 20.3 11.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3337 PF11816.8 OWF38425.1 - 0.0017 18.2 1.0 0.0054 16.6 0.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) zf-RING_5 PF14634.6 OWF38425.1 - 0.0029 17.5 13.4 0.0029 17.5 13.4 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF38425.1 - 0.0072 16.5 8.1 0.0072 16.5 8.1 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OWF38425.1 - 0.0072 16.4 10.8 0.046 13.9 6.1 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OWF38425.1 - 0.0098 15.7 9.9 0.0098 15.7 9.9 2.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF38425.1 - 0.029 14.7 9.2 0.029 14.7 9.2 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain UvrD-helicase PF00580.21 OWF38425.1 - 0.036 13.6 3.4 0.045 13.3 3.4 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PPV_E1_N PF00524.18 OWF38425.1 - 0.15 12.5 1.1 0.27 11.7 1.1 1.5 1 1 0 1 1 1 0 E1 Protein, N terminal domain zf-C3HC4_5 PF17121.5 OWF38425.1 - 0.17 11.8 5.7 0.56 10.1 5.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OWF38425.1 - 0.24 11.5 9.6 1.6 8.8 7.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 OWF38425.1 - 0.33 10.8 11.2 0.36 10.6 7.5 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 OWF38425.1 - 0.45 10.4 6.7 0.8 9.6 6.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 OWF38425.1 - 0.55 10.4 4.8 0.61 10.2 1.8 2.6 3 0 0 3 3 3 0 Zinc-binding RING-finger DUF1272 PF06906.11 OWF38425.1 - 3.5 7.8 10.9 2.7 8.1 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) IBR PF01485.21 OWF38425.1 - 5.2 7.4 13.8 33 4.8 0.2 3.2 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Homeodomain PF00046.29 OWF38426.1 - 4e-21 74.6 4.2 7.9e-21 73.7 4.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF38426.1 - 0.069 13.1 0.2 0.24 11.3 0.2 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF1720 PF08226.11 OWF38427.1 - 0.87 10.0 20.3 1.1e+02 3.3 20.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Vault PF01505.18 OWF38427.1 - 1 9.6 3.7 5.6 7.2 0.6 3.1 2 1 0 3 3 3 0 Major Vault Protein repeat domain fn1 PF00039.18 OWF38427.1 - 1.4 9.2 11.6 0.12 12.5 2.0 3.1 1 1 2 3 3 3 0 Fibronectin type I domain DUF1336 PF07059.12 OWF38427.1 - 5.4 7.0 6.0 52 3.8 0.1 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1336) ETF_QO PF05187.13 OWF38428.1 - 0.011 15.8 23.6 3.3 7.9 0.8 6.1 1 1 5 6 6 6 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S ATS3 PF06232.11 OWF38428.1 - 0.11 12.4 2.2 29 4.6 0.1 3.8 1 1 4 5 5 5 0 Embryo-specific protein 3, (ATS3) SEP PF08059.13 OWF38428.1 - 0.14 12.7 7.6 84 3.8 0.5 4.8 1 1 2 3 3 3 0 SEP domain RGM_C PF06534.13 OWF38428.1 - 1.4 8.4 6.7 14 5.2 0.5 3.6 1 1 2 3 3 3 0 Repulsive guidance molecule (RGM) C-terminus RelB PF04221.12 OWF38428.1 - 2.4 8.2 16.6 13 5.8 0.2 4.7 1 1 2 3 3 3 0 RelB antitoxin ubiquitin PF00240.23 OWF38428.1 - 5.3 6.9 6.0 1e+02 2.7 0.0 4.7 3 1 0 5 5 5 0 Ubiquitin family LETM1 PF07766.13 OWF38429.1 - 1.7e-96 322.7 13.0 1.7e-96 322.7 13.0 2.9 3 1 1 4 4 4 1 LETM1-like protein EF-hand_7 PF13499.6 OWF38429.1 - 1.6 9.2 7.3 1.2 9.7 0.1 3.9 2 2 1 3 3 3 0 EF-hand domain pair LSDAT_euk PF18139.1 OWF38430.1 - 6.3e-73 245.4 0.0 9.8e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF38430.1 - 2.6e-23 82.3 0.0 4.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 OWF38430.1 - 1.3e-06 27.8 25.2 2.8e-06 26.8 25.2 1.5 1 0 0 1 1 1 1 Ion transport protein AAA_23 PF13476.6 OWF38430.1 - 0.038 14.5 19.5 2.4 8.6 14.3 3.4 3 0 0 3 3 3 0 AAA domain BUD22 PF09073.10 OWF38430.1 - 1.6 8.0 27.2 0.11 11.8 21.3 1.9 2 0 0 2 2 2 0 BUD22 Endomucin PF07010.12 OWF38431.1 - 0.0068 16.4 19.2 0.058 13.4 7.6 2.2 2 0 0 2 2 2 2 Endomucin Lectin_C PF00059.21 OWF38431.1 - 0.05 14.3 0.2 0.05 14.3 0.2 2.4 2 0 0 2 2 2 0 Lectin C-type domain Ribosomal_L28e PF01778.17 OWF38432.1 - 1.3e-37 129.0 1.1 1.3e-37 129.0 1.1 2.1 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 OWF38432.1 - 4.1e-31 107.5 23.5 4.1e-31 107.5 23.5 2.2 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OWF38432.1 - 0.0023 17.4 22.1 0.0027 17.1 22.1 1.1 1 0 0 1 1 1 1 BUD22 CDC27 PF09507.10 OWF38432.1 - 0.15 11.4 21.9 0.19 11.1 21.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SKA1 PF07160.12 OWF38432.1 - 1.3 8.8 15.4 0.025 14.4 8.1 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Asp-B-Hydro_N PF05279.11 OWF38432.1 - 8.5 6.4 28.6 12 5.9 28.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ephrin_rec_like PF07699.13 OWF38433.1 - 1.2e-44 149.9 152.8 9.7e-08 31.7 11.8 13.8 2 1 15 17 17 17 15 Putative ephrin-receptor like NCD3G PF07562.14 OWF38433.1 - 6.3e-12 45.3 114.6 0.00019 21.3 1.2 11.9 6 2 3 11 11 11 10 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 OWF38433.1 - 0.063 13.7 118.8 0.48 10.9 2.5 15.4 3 3 11 15 15 15 0 TNFR/NGFR cysteine-rich region YaiA PF16362.5 OWF38434.1 - 0.048 13.8 1.2 4.4 7.5 0.1 3.4 1 1 4 5 5 5 0 YaiA protein C1q PF00386.21 OWF38435.1 - 3e-23 82.4 0.2 6.1e-23 81.4 0.1 1.6 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF38435.1 - 0.0011 18.9 1.5 0.0018 18.2 1.5 1.4 1 0 0 1 1 1 1 BclA C-terminal domain PA14 PF07691.12 OWF38435.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 PA14 domain DUF4349 PF14257.6 OWF38435.1 - 0.038 13.4 0.7 0.1 12.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) ZapB PF06005.12 OWF38435.1 - 0.063 13.7 0.3 0.11 13.0 0.3 1.3 1 0 0 1 1 1 0 Cell division protein ZapB MKLP1_Arf_bdg PF16540.5 OWF38435.1 - 0.068 13.2 0.2 0.41 10.7 0.2 2.0 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 GIT_CC PF16559.5 OWF38435.1 - 0.079 12.8 0.8 0.2 11.6 0.8 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor BTRD1 PF17660.1 OWF38435.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Cep57_CLD_2 PF14197.6 OWF38435.1 - 0.2 11.8 1.5 0.23 11.5 0.4 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 7tm_1 PF00001.21 OWF38436.1 - 6.8e-74 248.5 14.3 9e-74 248.1 14.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF38436.1 - 6.6e-11 42.1 16.2 9.3e-11 41.6 16.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF38436.1 - 4.3e-08 33.1 17.3 4.3e-08 33.1 17.3 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF38436.1 - 7.9e-06 25.8 16.2 0.00035 20.4 13.3 3.0 2 1 1 3 3 3 2 Olfactory receptor 7TM_GPCR_Srb PF02175.16 OWF38436.1 - 0.37 10.5 13.1 1.3 8.7 13.1 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb YkuD_2 PF13645.6 OWF38437.1 - 0.0084 15.6 1.0 46 3.4 0.0 5.2 4 1 1 6 6 6 1 L,D-transpeptidase catalytic domain SLY PF12485.8 OWF38437.1 - 1.2 9.8 22.2 3 8.6 0.8 4.7 1 1 3 4 4 4 0 Lymphocyte signaling adaptor protein DUF1961 PF09224.11 OWF38438.1 - 0.47 9.8 1.9 69 2.7 0.0 3.5 2 2 0 3 3 3 0 Domain of unknown function (DUF1961) DUF21 PF01595.20 OWF38439.1 - 3.8e-38 130.9 0.0 6.6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OWF38439.1 - 3.6e-08 33.7 0.8 0.002 18.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain Ras PF00071.22 OWF38440.1 - 2.2e-43 147.7 0.4 2.8e-43 147.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF38440.1 - 8.6e-30 103.4 0.1 1.3e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF38440.1 - 1.9e-14 53.5 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF38440.1 - 0.00011 21.6 0.1 0.00017 21.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OWF38440.1 - 0.0043 16.8 0.1 0.89 9.3 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OWF38440.1 - 0.092 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF38440.1 - 0.11 12.5 0.1 5.4 6.9 0.0 2.6 1 1 2 3 3 3 0 RsgA GTPase Lectin_leg-like PF03388.13 OWF38441.1 - 6.2e-95 316.9 0.4 7.4e-95 316.7 0.4 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 OWF38441.1 - 1.2e-07 31.9 1.6 1.7e-07 31.4 1.6 1.1 1 0 0 1 1 1 1 Bacterial lectin DUF5491 PF17595.2 OWF38441.1 - 0.0097 16.2 0.1 0.029 14.7 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5491) Laminin_G_2 PF02210.24 OWF38441.1 - 0.07 13.7 0.3 0.72 10.4 0.0 2.0 1 1 1 2 2 2 0 Laminin G domain PriA_C PF18074.1 OWF38442.1 - 0.0011 19.8 0.0 1.2e+02 3.6 0.0 6.4 4 2 3 7 7 7 0 Primosomal protein N C-terminal domain DUF3277 PF11681.8 OWF38442.1 - 0.12 12.3 16.8 55 3.6 0.1 8.2 5 3 6 11 11 11 0 Protein of unknown function (DUF3277) TamB PF04357.13 OWF38442.1 - 1.2 8.3 19.0 1.6 7.8 1.3 5.7 3 2 4 7 7 7 0 TamB, inner membrane protein subunit of TAM complex DUF3429 PF11911.8 OWF38442.1 - 2.6 8.3 16.3 1.2e+02 2.9 0.2 8.1 8 2 1 9 9 9 0 Protein of unknown function (DUF3429) Nup84_Nup100 PF04121.13 OWF38444.1 - 2.8e-195 650.6 15.1 3.3e-195 650.4 15.1 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TetR_C_28 PF17937.1 OWF38444.1 - 0.011 16.2 0.0 0.05 14.0 0.0 2.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RPAP3_C PF13877.6 OWF38444.1 - 0.037 14.6 1.2 0.13 12.8 1.2 2.0 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Imm-NTF2 PF15655.6 OWF38444.1 - 0.04 14.2 0.1 0.14 12.4 0.1 2.0 1 0 0 1 1 1 0 NTF2 fold immunity protein UPF0203 PF05254.12 OWF38444.1 - 0.082 13.2 0.3 0.49 10.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) CHCH PF06747.13 OWF38444.1 - 0.1 12.8 0.1 0.31 11.2 0.1 1.9 1 0 0 1 1 1 0 CHCH domain RIH_assoc PF08454.11 OWF38444.1 - 0.21 11.5 1.5 0.33 10.8 0.2 2.1 2 0 0 2 2 2 0 RyR and IP3R Homology associated BCIP PF13862.6 OWF38445.1 - 2.3e-53 181.1 4.0 3.3e-53 180.6 4.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PilW PF16074.5 OWF38445.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W Reprolysin PF01421.19 OWF38446.1 - 1.2e-52 178.7 0.0 2.3e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 OWF38446.1 - 3.4e-28 98.4 3.1 3.4e-28 98.4 3.1 3.5 3 0 0 3 3 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 OWF38446.1 - 7.1e-22 78.2 0.1 1.8e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 OWF38446.1 - 6.9e-20 72.0 0.1 6.9e-20 72.0 0.1 2.2 2 0 0 2 2 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 OWF38446.1 - 1.2e-18 67.6 32.0 1.2e-18 67.6 32.0 3.9 4 0 0 4 4 3 1 Disintegrin Reprolysin_3 PF13582.6 OWF38446.1 - 2.3e-12 47.5 0.2 6.9e-12 46.0 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF38446.1 - 5.3e-11 42.8 0.1 1.2e-10 41.6 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF38446.1 - 1.3e-07 31.5 0.1 2.6e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 OWF38446.1 - 0.011 16.1 11.8 0.011 16.1 11.8 4.7 5 1 0 5 5 2 0 EGF-like domain Zincin_1 PF06262.11 OWF38446.1 - 0.069 13.3 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M54 PF07998.11 OWF38446.1 - 0.15 12.0 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M54 CCDC142 PF14923.6 OWF38447.1 - 3.5e-92 309.5 1.5 5.7e-92 308.8 1.5 1.3 1 0 0 1 1 1 1 Coiled-coil protein 142 RINT1_TIP1 PF04437.13 OWF38447.1 - 0.0047 15.9 0.6 0.01 14.8 0.6 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family FANCI_S4 PF14678.6 OWF38448.1 - 2.5e-85 285.6 6.0 7.8e-85 284.0 6.0 2.0 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_HD2 PF14680.6 OWF38448.1 - 1.3e-84 283.2 2.0 1.3e-84 283.2 2.0 2.7 3 0 0 3 3 3 1 FANCI helical domain 2 FANCI_S1 PF14675.6 OWF38448.1 - 3.1e-68 229.7 1.2 3.1e-68 229.7 1.2 2.3 2 0 0 2 2 2 1 FANCI solenoid 1 FANCI_S2 PF14676.6 OWF38448.1 - 1.3e-55 188.2 0.2 1.3e-55 188.2 0.2 3.9 3 2 0 3 3 3 1 FANCI solenoid 2 FANCI_S3 PF14677.6 OWF38448.1 - 3.6e-41 141.2 3.2 3.6e-41 141.2 3.2 4.0 4 0 0 4 4 4 1 FANCI solenoid 3 FANCI_HD1 PF14679.6 OWF38448.1 - 9.5e-31 105.6 0.7 3.2e-30 103.9 0.7 2.0 1 0 0 1 1 1 1 FANCI helical domain 1 FANCI_S1-cap PF14674.6 OWF38448.1 - 5.3e-07 29.6 0.4 2e-06 27.8 0.4 2.2 1 0 0 1 1 1 1 FANCI solenoid 1 cap Bcl-2 PF00452.19 OWF38448.1 - 4.8e-05 24.0 0.6 0.046 14.4 0.1 3.6 3 0 0 3 3 3 1 Apoptosis regulator proteins, Bcl-2 family HSP70 PF00012.20 OWF38450.1 - 2.4e-95 320.0 0.3 2.7e-95 319.8 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF38450.1 - 5e-11 42.0 0.6 1.7e-10 40.2 0.3 1.8 2 0 0 2 2 2 1 MreB/Mbl protein DUF1918 PF08940.11 OWF38450.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) FGGY_C PF02782.16 OWF38450.1 - 0.039 13.7 0.4 0.31 10.7 0.2 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain PilM_2 PF11104.8 OWF38450.1 - 0.12 11.4 0.1 4.1 6.3 0.0 2.4 2 1 0 2 2 2 0 Type IV pilus assembly protein PilM; Armet PF10208.9 OWF38451.1 - 3.3e-51 173.0 10.6 5.4e-51 172.3 10.6 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Epsilon_antitox PF08998.11 OWF38451.1 - 0.059 13.6 0.4 0.14 12.4 0.1 1.8 2 1 0 2 2 2 0 Bacterial epsilon antitoxin HeH PF12949.7 OWF38451.1 - 0.075 12.8 0.2 0.26 11.0 0.2 1.9 2 0 0 2 2 2 0 HeH/LEM domain Peptidase_M20 PF01546.28 OWF38452.1 - 3.7e-35 121.5 0.0 7.1e-35 120.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OWF38452.1 - 8.8e-14 51.4 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OWF38452.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 7tm_1 PF00001.21 OWF38453.1 - 1.5e-27 96.6 27.0 2.2e-27 96.0 27.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF38453.1 - 1.9e-17 63.6 35.1 2.6e-17 63.1 35.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF38453.1 - 1.3e-05 25.0 23.9 1.3e-05 25.0 23.9 2.7 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Ank_2 PF12796.7 OWF38454.1 - 2.7e-28 98.4 7.7 8.4e-13 48.7 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF38454.1 - 3.4e-22 78.2 0.9 7.1e-10 39.0 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF38454.1 - 1e-17 64.2 2.3 6.4e-10 39.4 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF38454.1 - 2.2e-16 59.4 3.8 0.0005 20.4 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 OWF38454.1 - 1.5e-13 49.6 0.8 0.012 16.1 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat P2_N PF18628.1 OWF38454.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain LSM PF01423.22 OWF38455.1 - 6.3e-21 73.8 0.0 7.6e-21 73.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OWF38455.1 - 0.046 13.9 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Med20 PF08612.11 OWF38456.1 - 1e-38 132.9 0.0 1.3e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Cytochrom_NNT PF03264.14 OWF38456.1 - 0.018 14.7 0.5 0.034 13.8 0.5 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Urocanase_C PF17392.2 OWF38457.1 - 8.2e-89 296.2 1.6 1.4e-88 295.5 1.6 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 OWF38457.1 - 3.5e-87 291.5 0.0 5.6e-87 290.8 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 OWF38457.1 - 1.1e-55 186.7 0.0 2.8e-55 185.4 0.0 1.7 1 0 0 1 1 1 1 Urocanase N-terminal domain Nuc_sug_transp PF04142.15 OWF38458.1 - 2.4e-126 421.2 26.5 2.9e-126 420.9 26.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OWF38458.1 - 6.2e-08 32.9 28.6 2.6e-05 24.4 4.6 3.1 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 OWF38458.1 - 1.6e-05 24.3 17.9 1.6e-05 24.3 17.9 3.3 1 1 1 2 2 2 2 UAA transporter family PUNUT PF16913.5 OWF38458.1 - 0.018 14.3 26.4 0.026 13.8 26.4 1.2 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport DUF202 PF02656.15 OWF38458.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF3377 PF11857.8 OWF38458.1 - 5.1 7.1 7.7 20 5.2 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3377) PHR PF08005.12 OWF38459.1 - 1.9e-32 113.0 0.2 3.3e-32 112.2 0.2 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 OWF38459.1 - 1.2e-27 96.3 2.2 1.5e-23 83.1 0.1 2.5 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 OWF38459.1 - 2.3e-17 63.0 1.1 1.4e-16 60.5 0.4 2.6 3 1 0 3 3 3 1 BTB And C-terminal Kelch Aminotran_1_2 PF00155.21 OWF38460.1 - 1.1e-36 126.8 0.0 1.5e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CBM_14 PF01607.24 OWF38461.1 - 1.1e-19 70.3 37.4 6.4e-08 32.7 2.9 5.5 5 1 0 5 5 5 4 Chitin binding Peritrophin-A domain Tyrosinase PF00264.20 OWF38462.1 - 9.5e-32 111.1 5.6 5.7e-30 105.3 1.7 3.1 2 1 0 2 2 2 1 Common central domain of tyrosinase UPAR_LY6 PF00021.21 OWF38462.1 - 0.19 12.4 3.9 0.42 11.3 3.9 1.5 1 0 0 1 1 1 0 u-PAR/Ly-6 domain GST_C_3 PF14497.6 OWF38463.1 - 8.2e-20 70.9 1.2 1.2e-19 70.4 1.2 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF38463.1 - 1.9e-08 34.4 0.1 3.4e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF38464.1 - 3.3e-20 72.1 0.2 4.6e-20 71.7 0.2 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF38464.1 - 1.5e-12 47.7 0.0 3.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF38464.1 - 2e-07 31.1 0.1 3.5e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF38464.1 - 8.8e-07 29.2 0.0 3.8e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF38464.1 - 0.00049 20.8 0.0 0.0044 17.7 0.0 2.4 2 1 1 3 3 3 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OWF38464.1 - 0.0014 19.0 0.0 0.003 17.8 0.0 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.6 OWF38464.1 - 0.0026 18.0 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF5636 PF18686.1 OWF38464.1 - 0.026 14.7 0.2 0.033 14.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5636) GST_C_2 PF13410.6 OWF38464.1 - 0.082 12.9 0.0 0.3 11.1 0.1 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF38465.1 - 1.1e-17 64.0 0.1 1.9e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF38465.1 - 2.2e-11 43.9 0.2 1.7e-10 41.1 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF38465.1 - 1.1e-07 32.1 0.0 6.8e-07 29.6 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF38465.1 - 1.5e-07 31.5 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF38465.1 - 0.00084 20.0 0.0 0.0031 18.2 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OWF38465.1 - 0.00093 19.5 0.0 0.0026 18.1 0.0 1.7 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.6 OWF38465.1 - 0.0032 17.7 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Globin PF00042.22 OWF38465.1 - 0.05 14.2 0.0 1.8 9.1 0.1 2.6 2 1 1 3 3 3 0 Globin GST_C_3 PF14497.6 OWF38466.1 - 5.6e-20 71.4 2.0 8.3e-20 70.8 2.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF38466.1 - 1.1e-09 38.5 0.3 1.4e-08 34.9 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF38466.1 - 1.5e-07 31.6 0.5 2.6e-07 30.8 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF38466.1 - 0.00034 21.3 0.0 0.00056 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 OWF38466.1 - 0.0008 19.4 0.1 0.0022 18.0 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF38466.1 - 0.001 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 OWF38466.1 - 0.0018 18.6 0.0 0.0028 17.9 0.0 1.5 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.6 OWF38466.1 - 0.029 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF38467.1 - 1.9e-20 72.9 0.6 2.5e-20 72.5 0.6 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF38467.1 - 9.4e-09 35.4 0.1 1.5e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF38467.1 - 0.0009 19.9 0.0 0.004 17.9 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 OWF38467.1 - 0.0013 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF38467.1 - 0.0025 18.1 0.0 0.0066 16.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF38467.1 - 0.0096 16.3 0.0 0.025 15.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF38468.1 - 6.1e-17 61.6 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF38468.1 - 4e-10 39.9 0.0 9.5e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF38468.1 - 1.4e-05 25.4 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF38468.1 - 0.00034 20.8 0.0 0.00059 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF38468.1 - 0.043 14.6 0.0 0.081 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 OWF38468.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF38469.1 - 3.7e-19 68.7 0.6 6.2e-19 68.0 0.6 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF38469.1 - 1.6e-12 47.6 0.0 1.3e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF38469.1 - 5.7e-07 29.7 0.2 1.1e-06 28.8 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF38469.1 - 0.0001 22.6 0.0 0.00023 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF38469.1 - 0.00027 20.9 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF38469.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain L51_S25_CI-B8 PF05047.16 OWF38471.1 - 1.1e-12 47.7 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sec3_C PF09763.9 OWF38472.1 - 4.6e-28 98.1 0.4 5.5e-28 97.8 0.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3_C PF09763.9 OWF38473.1 - 1.1e-112 377.8 11.7 1.6e-112 377.2 11.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OWF38473.1 - 6.3e-23 80.7 3.7 2e-22 79.1 3.7 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF4525 PF15027.6 OWF38473.1 - 0.016 14.9 0.8 2.6 7.8 0.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4525) EMP24_GP25L PF01105.24 OWF38473.1 - 0.038 13.9 2.9 0.38 10.7 1.7 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Ubiq_cyt_C_chap PF03981.12 OWF38473.1 - 1.1 9.3 3.7 2.1 8.4 1.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone Fes1 PF08609.10 OWF38473.1 - 5.5 7.9 9.2 7.6 7.5 0.3 3.3 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 APG6_N PF17675.1 OWF38473.1 - 6.2 7.4 12.7 23 5.5 3.4 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region Neurexophilin PF06312.12 OWF38474.1 - 1.6e-08 34.3 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF38474.1 - 0.06 14.2 0.0 0.16 12.8 0.0 1.7 1 0 0 1 1 1 0 Filamin/ABP280 repeat START PF01852.19 OWF38475.1 - 3.5e-30 105.0 0.1 4.5e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 OWF38475.1 - 0.0079 16.2 0.0 0.028 14.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Voltage_CLC PF00654.20 OWF38476.1 - 8.6e-101 337.7 21.2 5.5e-99 331.8 19.4 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel ThrE PF06738.12 OWF38476.1 - 0.36 10.2 0.0 0.36 10.2 0.0 3.9 4 1 0 4 4 4 0 Putative threonine/serine exporter adh_short PF00106.25 OWF38477.1 - 7.6e-38 129.9 0.0 9.4e-29 100.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38477.1 - 3e-26 92.4 0.0 4.5e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38477.1 - 1.8e-08 34.5 0.0 3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF38477.1 - 6.9e-06 25.7 0.0 3.9e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OWF38478.1 - 2e-36 125.3 0.0 6.6e-28 97.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38478.1 - 2.4e-25 89.5 0.0 1.2e-20 74.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38478.1 - 5.7e-08 32.9 0.0 8.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF38478.1 - 4.9e-06 26.2 0.0 1.3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Noelin-1 PF12308.8 OWF38478.1 - 0.086 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein adh_short PF00106.25 OWF38479.1 - 5.1e-29 101.1 0.0 1.1e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38479.1 - 1.7e-18 67.0 0.0 2.4e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38479.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF38479.1 - 4.9e-05 22.9 0.0 0.00031 20.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 OWF38479.1 - 0.11 13.1 0.1 0.62 10.6 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAST_1 PF06743.15 OWF38480.1 - 0.00033 20.5 0.5 0.012 15.6 0.1 3.3 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 DUF1722 PF08349.11 OWF38480.1 - 0.014 15.6 1.5 2 8.7 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) MOR2-PAG1_N PF14222.6 OWF38481.1 - 4.3e-159 531.0 7.3 7.5e-159 530.2 7.3 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OWF38481.1 - 5e-71 239.5 8.6 5.5e-71 239.4 0.2 4.1 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OWF38481.1 - 1.7e-35 122.1 12.5 1.5e-09 36.1 0.1 5.6 4 1 0 5 5 5 5 Cell morphogenesis central region HEAT_2 PF13646.6 OWF38481.1 - 0.015 15.6 0.0 0.23 11.9 0.0 3.1 2 0 0 2 2 2 0 HEAT repeats AAA_11 PF13086.6 OWF38482.1 - 2.2e-57 194.8 0.4 2.2e-57 194.8 0.4 3.7 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 OWF38482.1 - 1.6e-52 178.0 0.2 4.4e-52 176.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain R3H PF01424.22 OWF38482.1 - 1.8e-12 47.0 0.0 4.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain AAA_30 PF13604.6 OWF38482.1 - 2.1e-12 47.2 0.0 4.4e-11 42.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF38482.1 - 1.1e-09 38.8 0.1 2.8e-09 37.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain zf-AN1 PF01428.16 OWF38482.1 - 5.2e-08 32.9 7.9 5.2e-08 32.9 7.9 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger Viral_helicase1 PF01443.18 OWF38482.1 - 8.9e-06 25.6 2.5 0.6 9.8 0.1 4.1 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OWF38482.1 - 4.1e-05 23.7 1.0 0.00043 20.3 0.1 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 OWF38482.1 - 0.00026 20.9 0.3 0.0034 17.3 0.3 2.6 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 OWF38482.1 - 0.00036 20.9 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 OWF38482.1 - 0.00059 19.6 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Glyco_tranf_2_3 PF13641.6 OWF38482.1 - 0.0017 18.3 0.1 0.0075 16.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 AAA_22 PF13401.6 OWF38482.1 - 0.0029 17.9 0.0 0.033 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OWF38482.1 - 0.0051 17.2 0.0 0.016 15.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Glycos_transf_2 PF00535.26 OWF38482.1 - 0.0056 16.5 0.0 0.63 9.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DEAD PF00270.29 OWF38482.1 - 0.0076 16.0 2.6 0.063 13.0 0.4 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Lipase_GDSL_3 PF14606.6 OWF38482.1 - 0.028 14.6 0.2 12 6.0 0.0 2.7 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2075 PF09848.9 OWF38482.1 - 0.032 13.5 3.3 0.16 11.2 0.7 3.1 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 OWF38482.1 - 0.041 12.9 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OWF38482.1 - 0.043 14.3 0.3 0.15 12.6 0.0 2.1 2 0 0 2 2 1 0 ABC transporter UvrD-helicase PF00580.21 OWF38482.1 - 0.057 12.9 0.1 0.057 12.9 0.1 2.4 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain ATPase_2 PF01637.18 OWF38482.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Flavi_DEAD PF07652.14 OWF38482.1 - 0.19 11.7 1.9 0.39 10.7 0.2 2.3 3 0 0 3 3 3 0 Flavivirus DEAD domain AAA_33 PF13671.6 OWF38482.1 - 0.25 11.5 1.3 0.68 10.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OWF38482.1 - 0.6 10.6 8.6 0.11 12.9 0.2 3.2 2 2 0 2 2 2 0 AAA domain DUF2370 PF10176.9 OWF38483.1 - 4.3e-08 33.1 4.7 1.2e-06 28.4 0.6 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) DUF4719 PF15843.5 OWF38483.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) DUF5310 PF17237.2 OWF38483.1 - 0.2 11.6 3.6 0.45 10.4 3.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Ank_2 PF12796.7 OWF38484.1 - 4.9e-48 161.6 1.0 4.1e-15 56.1 0.0 4.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF38484.1 - 1.1e-27 93.0 2.3 3.8e-05 23.7 0.0 8.0 7 2 1 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OWF38484.1 - 1.1e-24 86.4 0.1 1.7e-05 25.3 0.0 6.1 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF38484.1 - 4.6e-24 84.2 0.9 6.1e-08 32.8 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF38484.1 - 6.9e-24 83.2 0.8 0.00013 22.3 0.0 6.9 6 1 1 7 7 7 4 Ankyrin repeat SOCS_box PF07525.16 OWF38484.1 - 9.4e-09 35.5 0.1 1.8e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 SOCS box FAD_binding_2 PF00890.24 OWF38484.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TED_complement PF07678.14 OWF38485.1 - 4e-97 325.0 0.0 6e-97 324.4 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 OWF38485.1 - 3.6e-33 114.9 0.4 1e-30 107.0 0.1 3.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 OWF38485.1 - 1.9e-27 95.0 1.8 6.3e-27 93.3 0.3 2.9 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 OWF38485.1 - 1.1e-22 80.5 0.0 6e-22 78.1 0.0 2.4 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 OWF38485.1 - 6.1e-19 68.1 0.2 2.9e-18 65.9 0.2 2.3 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 OWF38485.1 - 3.9e-15 56.1 0.1 2.6e-13 50.2 0.0 3.6 3 0 0 3 3 2 1 MG2 domain SQHop_cyclase_C PF13243.6 OWF38485.1 - 0.0034 16.5 0.0 0.014 14.5 0.0 1.9 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain MG4 PF17789.1 OWF38485.1 - 0.0081 16.3 9.5 0.072 13.2 0.1 4.9 5 1 0 5 5 5 1 Macroglobulin domain MG4 MG1 PF17790.1 OWF38485.1 - 0.028 14.8 7.5 0.037 14.5 0.1 4.5 5 0 0 5 5 5 0 Macroglobulin domain MG1 DUF4469 PF14734.6 OWF38485.1 - 0.059 13.5 0.0 0.23 11.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold NPCBM_assoc PF10633.9 OWF38485.1 - 0.065 13.5 0.3 1.8 8.8 0.0 3.2 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Globin PF00042.22 OWF38486.1 - 6.9e-20 71.7 0.0 1.2e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Globin Globin PF00042.22 OWF38487.1 - 8.4e-18 64.9 0.0 1.4e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Globin Globin PF00042.22 OWF38488.1 - 7.6e-05 23.2 0.1 0.00018 22.0 0.0 1.6 2 0 0 2 2 2 1 Globin TED_complement PF07678.14 OWF38489.1 - 1.1e-95 320.3 0.0 1.7e-95 319.7 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 OWF38489.1 - 2.2e-33 115.6 0.7 5.5e-31 107.8 0.4 3.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 OWF38489.1 - 2e-27 94.9 2.3 4.2e-27 93.8 0.4 2.7 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 OWF38489.1 - 2e-25 89.3 0.1 1.1e-24 86.9 0.1 2.4 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 OWF38489.1 - 2.3e-16 59.8 0.0 1e-15 57.7 0.0 2.3 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 OWF38489.1 - 4.6e-15 55.8 0.2 2.8e-13 50.1 0.0 3.9 4 0 0 4 4 3 1 MG2 domain MG4 PF17789.1 OWF38489.1 - 0.00043 20.4 6.9 0.026 14.7 0.1 4.5 4 0 0 4 4 4 1 Macroglobulin domain MG4 MG1 PF17790.1 OWF38489.1 - 0.0032 17.8 5.0 0.041 14.3 0.2 4.0 4 0 0 4 4 4 1 Macroglobulin domain MG1 SQHop_cyclase_C PF13243.6 OWF38489.1 - 0.0053 15.9 0.0 0.024 13.7 0.0 1.8 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain NPCBM_assoc PF10633.9 OWF38489.1 - 0.093 13.0 0.2 1.9 8.8 0.0 3.2 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Omp28 PF11551.8 OWF38489.1 - 2.4 8.0 5.1 0.65 9.8 0.1 2.6 3 0 0 3 3 3 0 Outer membrane protein Omp28 SH3_9 PF14604.6 OWF38490.1 - 1.3e-53 178.6 4.9 1e-11 44.5 0.0 5.3 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 OWF38490.1 - 6.9e-52 172.8 8.2 1.2e-12 47.2 0.0 6.1 6 0 0 6 6 6 5 SH3 domain SH3_2 PF07653.17 OWF38490.1 - 1.9e-37 126.7 1.8 1.7e-08 34.0 0.2 5.4 5 0 0 5 5 5 5 Variant SH3 domain RCC1 PF00415.18 OWF38491.1 - 1.1e-227 736.7 90.5 1.5e-14 54.3 0.0 20.8 20 0 0 20 20 20 19 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF38491.1 - 9.2e-87 283.5 124.4 1.2e-09 37.7 0.2 22.3 23 0 0 23 23 22 15 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 OWF38491.1 - 9.6e-56 189.5 0.0 3.3e-55 187.8 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Cul7 PF11515.8 OWF38491.1 - 2.8e-33 114.0 0.6 7.9e-33 112.6 0.6 1.8 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 MIB_HERC2 PF06701.13 OWF38491.1 - 2.1e-22 79.2 4.6 2.1e-22 79.2 4.6 4.6 6 0 0 6 6 5 1 Mib_herc2 Cyt-b5 PF00173.28 OWF38491.1 - 1.1e-19 70.3 0.5 4.5e-18 65.2 0.1 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.17 OWF38491.1 - 1.8e-09 37.3 6.0 4.2e-09 36.1 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type SH3_15 PF18346.1 OWF38491.1 - 1.5e-07 31.6 2.5 8e-06 26.1 0.2 3.7 3 0 0 3 3 3 1 Mind bomb SH3 repeat domain ANAPC10 PF03256.16 OWF38491.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) UBA PF00627.31 OWF38491.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Ubie_methyltran PF01209.18 OWF38491.1 - 0.28 10.5 1.3 14 4.9 0.0 3.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MCLC PF05934.11 OWF38492.1 - 2.6e-16 59.5 4.6 3.7e-16 59.0 4.6 1.1 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) SNARE_assoc PF09335.11 OWF38492.1 - 0.003 18.1 0.8 0.1 13.1 0.0 2.7 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF3328 PF11807.8 OWF38492.1 - 0.0098 15.7 0.3 0.21 11.3 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3328) Pex24p PF06398.11 OWF38492.1 - 0.016 14.2 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin EphA2_TM PF14575.6 OWF38492.1 - 0.044 14.6 5.2 0.14 13.1 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain F_actin_bund_C PF18060.1 OWF38492.1 - 0.059 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 F actin bundling C terminal Haemocyan_bet_s PF14830.6 OWF38492.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich CD34_antigen PF06365.12 OWF38492.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.8 3 0 0 3 3 3 0 CD34/Podocalyxin family DENN PF02141.21 OWF38493.1 - 2.9e-36 125.2 2.3 7e-36 123.9 2.3 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OWF38493.1 - 7.3e-07 29.8 0.3 2.3e-06 28.2 0.3 1.9 1 0 0 1 1 1 1 uDENN domain ANAPC4_WD40 PF12894.7 OWF38493.1 - 0.0065 16.7 0.3 1.2 9.5 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain bPH_3 PF14470.6 OWF38493.1 - 0.0095 16.3 0.1 0.059 13.7 0.1 2.4 2 0 0 2 2 2 1 Bacterial PH domain dDENN PF03455.19 OWF38493.1 - 0.0096 15.9 2.7 0.0096 15.9 2.7 2.2 2 0 0 2 2 2 1 dDENN domain Vps36_ESCRT-II PF11605.8 OWF38493.1 - 0.014 15.6 0.1 0.047 13.9 0.1 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 WD40 PF00400.32 OWF38493.1 - 0.036 15.0 0.5 0.37 11.7 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat WD40_like PF17005.5 OWF38493.1 - 0.085 12.2 0.8 0.29 10.4 0.2 1.9 1 1 1 2 2 2 0 WD40-like domain 7tm_1 PF00001.21 OWF38494.1 - 1.7e-12 47.2 8.5 1.7e-12 47.2 8.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RGM_C PF06534.13 OWF38494.1 - 0.0079 15.7 0.8 0.016 14.7 0.8 1.5 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus BNR_assoc_N PF14873.6 OWF38494.1 - 0.024 14.3 0.2 0.044 13.5 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase FANCF PF11107.8 OWF38495.1 - 8.2e-22 77.9 1.1 9.4e-22 77.7 1.1 1.1 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) NUC202 PF08166.12 OWF38495.1 - 0.88 9.7 7.6 63 3.7 4.0 3.8 1 1 1 3 3 3 0 NUC202 domain LicD PF04991.13 OWF38496.1 - 0.0028 17.8 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 LicD family Peptidase_C14 PF00656.22 OWF38497.1 - 9.3e-44 150.2 0.4 1.4e-43 149.7 0.4 1.2 1 0 0 1 1 1 1 Caspase domain CARD_2 PF16739.5 OWF38497.1 - 0.0033 17.4 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain Peptidase_C14 PF00656.22 OWF38498.1 - 7e-38 131.0 0.3 1.1e-37 130.3 0.3 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 OWF38498.1 - 0.0079 16.2 0.0 0.037 14.0 0.0 2.1 2 0 0 2 2 2 1 Caspase recruitment domain PBECR2 PF18810.1 OWF38498.1 - 0.13 12.6 0.3 0.29 11.4 0.1 1.7 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Alpha-amylase PF00128.24 OWF38499.1 - 1.6e-93 314.0 1.7 2.5e-93 313.3 1.7 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OWF38499.1 - 2.5e-05 23.6 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 OWF38499.1 - 0.024 14.8 0.0 0.07 13.3 0.0 1.8 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 OWF38499.1 - 0.03 14.6 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) MFS_1 PF07690.16 OWF38500.1 - 2.4e-41 141.8 28.7 2.8e-35 121.9 21.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.11 OWF38500.1 - 0.00053 20.0 5.8 0.00053 20.0 5.8 3.6 4 0 0 4 4 4 1 7TM diverse intracellular signalling MFS_1_like PF12832.7 OWF38500.1 - 0.017 14.0 19.0 0.019 13.9 5.7 3.1 3 0 0 3 3 3 0 MFS_1 like family MFS_4 PF06779.14 OWF38500.1 - 0.027 13.8 0.0 0.027 13.8 0.0 3.3 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB DUF5527 PF17665.1 OWF38500.1 - 0.028 13.9 0.1 0.075 12.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Abhydrolase_9_N PF15420.6 OWF38500.1 - 0.14 12.2 8.4 0.025 14.6 1.7 2.6 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Protocadherin PF08374.11 OWF38500.1 - 0.15 12.1 0.3 3.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Protocadherin Viral_Beta_CD PF04530.12 OWF38500.1 - 0.36 11.1 6.4 20 5.5 0.1 4.0 3 1 1 4 4 4 0 Viral Beta C/D like family DUF4131 PF13567.6 OWF38500.1 - 0.58 9.8 13.3 5 6.7 0.1 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) PAS_11 PF14598.6 OWF38501.1 - 7.1e-11 42.2 1.2 5.7e-09 36.1 0.1 3.0 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.12 OWF38501.1 - 1.8e-10 40.9 0.0 1.2e-06 28.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 OWF38501.1 - 5.2e-07 29.5 0.3 1.1e-06 28.5 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 OWF38501.1 - 0.00026 20.9 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OWF38501.1 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain Na_sulph_symp PF00939.19 OWF38502.1 - 4.7e-46 157.8 23.6 6.4e-41 140.9 16.7 2.0 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF38502.1 - 3.5e-20 72.4 39.1 6.4e-12 45.3 19.7 1.9 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 OWF38503.1 - 4.2e-85 286.6 28.3 1.5e-57 195.7 19.1 2.0 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF38503.1 - 2.5e-28 99.2 62.8 3.8e-13 49.3 11.5 2.9 2 1 1 3 3 3 3 Citrate transporter Na_sulph_symp PF00939.19 OWF38504.1 - 7.8e-40 137.3 0.2 1e-39 136.9 0.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF38504.1 - 1.4e-14 54.0 17.0 4.1e-12 45.9 12.5 2.2 2 0 0 2 2 2 2 Citrate transporter SspP PF08179.12 OWF38504.1 - 4.7 7.8 4.8 0.69 10.4 0.6 1.8 2 0 0 2 2 2 0 Small acid-soluble spore protein P family zf-C2H2_3rep PF18868.1 OWF38505.1 - 0.0012 19.5 4.6 0.015 15.9 2.7 2.8 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 OWF38505.1 - 0.99 9.1 8.4 3.9 7.2 8.0 2.2 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 OWF38505.1 - 1.7 9.7 16.1 0.62 11.0 4.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger HSP70 PF00012.20 OWF38506.1 - 3.9e-15 55.1 0.2 9.7e-08 30.7 0.1 2.1 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OWF38506.1 - 0.00027 19.9 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 OWF38506.1 - 0.006 15.6 0.3 0.23 10.4 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 OWF38506.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Pga1 PF10333.9 OWF38506.1 - 0.19 11.6 0.7 14 5.5 0.0 2.3 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator HSP70 PF00012.20 OWF38507.1 - 4.9e-16 58.1 0.1 1.3e-08 33.6 0.0 2.2 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OWF38507.1 - 1.3e-05 24.2 0.0 0.0056 15.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 OWF38507.1 - 0.03 13.3 0.2 0.39 9.6 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 OWF38507.1 - 0.095 12.2 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HSP70 PF00012.20 OWF38508.1 - 2.2e-11 42.7 0.2 2.6e-09 35.8 0.2 2.2 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF38508.1 - 0.0014 17.5 0.2 0.052 12.4 0.0 2.4 1 1 1 2 2 2 2 MreB/Mbl protein DDR PF08841.10 OWF38508.1 - 0.22 10.5 0.2 8 5.3 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF4218 PF13960.6 OWF38509.1 - 1e-09 38.0 0.1 1.1e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Kelch_1 PF01344.25 OWF38510.1 - 7.6e-72 236.7 15.3 2.5e-13 49.4 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 OWF38510.1 - 1.8e-43 145.4 0.4 2.2e-09 37.2 0.0 6.5 2 1 4 6 6 6 6 Kelch motif BACK PF07707.15 OWF38510.1 - 3.6e-30 104.1 1.8 2.1e-29 101.6 0.9 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF38510.1 - 4.8e-29 100.8 2.0 1.2e-28 99.5 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 OWF38510.1 - 4.1e-24 83.6 1.8 1.4e-05 24.9 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OWF38510.1 - 1.2e-17 63.6 7.4 0.00019 21.4 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF38510.1 - 8.3e-12 45.1 7.1 0.00076 19.7 0.1 5.7 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF38510.1 - 2.1e-10 40.4 7.3 0.017 15.1 0.1 5.7 6 0 0 6 6 6 3 Kelch motif PQQ_3 PF13570.6 OWF38510.1 - 0.0051 17.3 3.0 3.5 8.3 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain DUF5122 PF17164.4 OWF38510.1 - 0.32 11.3 1.0 18 5.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller BaffR-Tall_bind PF09256.10 OWF38510.1 - 0.63 9.8 5.7 42 4.0 0.2 4.3 4 0 0 4 4 4 0 BAFF-R, TALL-1 binding DUF4698 PF15769.5 OWF38511.1 - 5e-68 230.4 24.1 8.5e-60 203.2 16.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4698) CD20 PF04103.15 OWF38512.1 - 4.3e-06 26.9 2.7 4.3e-06 26.9 2.7 2.3 1 1 1 2 2 2 1 CD20-like family DUF373 PF04123.13 OWF38512.1 - 0.0049 16.4 1.7 0.0062 16.0 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF373) SUR7 PF06687.12 OWF38512.1 - 0.062 12.9 3.3 0.31 10.6 3.0 2.0 1 1 0 1 1 1 0 SUR7/PalI family DUF3810 PF12725.7 OWF38512.1 - 0.084 12.2 3.8 0.11 11.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DHHC PF01529.20 OWF38512.1 - 0.14 12.3 7.4 0.32 11.1 7.4 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase TauE PF01925.19 OWF38512.1 - 0.25 10.9 6.0 55 3.3 0.0 2.8 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE Tetraspanin PF00335.20 OWF38512.1 - 1.3 8.7 10.6 2.7 7.6 9.3 2.0 1 1 1 2 2 2 0 Tetraspanin family DUF308 PF03729.13 OWF38512.1 - 2 8.8 14.0 0.55 10.6 0.4 2.9 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Cadherin PF00028.17 OWF38513.1 - 1.3e-22 80.0 12.3 1.1e-06 29.0 0.5 6.1 5 1 1 6 6 6 4 Cadherin domain DUF4690 PF15756.5 OWF38513.1 - 0.0043 17.6 2.1 0.0043 17.6 2.1 3.5 3 0 0 3 3 3 1 Small Novel Rich in Cartilage MGC-24 PF05283.11 OWF38513.1 - 0.013 16.0 8.4 0.013 16.0 8.4 2.9 3 1 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3948 PF13134.6 OWF38513.1 - 0.066 12.9 1.1 0.31 10.8 1.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) RET_CLD4 PF17813.1 OWF38513.1 - 0.15 12.3 1.4 0.42 10.9 1.4 1.8 1 0 0 1 1 1 0 RET Cadherin like domain 4 Yip1 PF04893.17 OWF38513.1 - 0.32 10.7 4.6 0.37 10.5 2.8 1.9 2 0 0 2 2 2 0 Yip1 domain Oxidored_q2 PF00420.24 OWF38513.1 - 1.5 8.5 6.1 4 7.1 6.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF3439 PF11921.8 OWF38513.1 - 5.4 7.0 20.7 1.4 8.9 15.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Cadherin PF00028.17 OWF38514.1 - 5.5e-25 87.6 13.4 3.2e-05 24.3 0.2 5.4 5 0 0 5 5 5 5 Cadherin domain PepSY PF03413.19 OWF38514.1 - 1.3e-05 25.6 0.3 0.97 10.0 0.1 3.8 3 0 0 3 3 3 3 Peptidase propeptide and YPEB domain DUF4690 PF15756.5 OWF38514.1 - 0.031 14.9 0.7 0.031 14.9 0.7 3.5 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF4713 PF15831.5 OWF38514.1 - 0.052 14.0 1.5 0.11 12.9 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) TNFR_16_TM PF18422.1 OWF38514.1 - 0.55 10.2 3.5 1.4 8.9 3.5 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Cadherin PF00028.17 OWF38515.1 - 5.8e-47 158.1 39.5 1.5e-10 41.4 1.3 12.1 11 1 0 11 11 11 7 Cadherin domain Cadherin_3 PF16184.5 OWF38515.1 - 0.0099 15.9 8.8 0.4 10.7 0.0 5.8 5 1 1 6 6 6 1 Cadherin-like DUF4625 PF15418.6 OWF38515.1 - 0.027 14.7 0.1 22 5.3 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4625) DUF678 PF05077.12 OWF38515.1 - 0.067 13.3 0.3 29 4.9 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DUF2057 PF09829.9 OWF38515.1 - 0.12 12.5 0.6 0.4 10.8 0.6 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) FlgD_ig PF13860.6 OWF38515.1 - 0.19 11.6 4.3 1.3 8.9 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain ig PF00047.25 OWF38515.1 - 0.54 10.5 9.3 3.2 8.0 0.1 4.6 5 0 0 5 5 5 0 Immunoglobulin domain Big_3_3 PF13750.6 OWF38515.1 - 0.58 9.8 14.7 0.33 10.6 0.2 5.1 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) YniB PF14002.6 OWF38516.1 - 0.047 13.5 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 YniB-like protein BIV_Env PF05858.12 OWF38516.1 - 0.053 11.7 0.0 0.077 11.2 0.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) SLC3A2_N PF16028.5 OWF38516.1 - 0.053 13.1 0.7 0.096 12.3 0.7 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus I-set PF07679.16 OWF38517.1 - 6.1e-17 61.5 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF38517.1 - 1.6e-14 54.2 0.2 1e-13 51.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 OWF38517.1 - 5.6e-10 39.4 1.1 1.1e-09 38.4 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 OWF38517.1 - 3.1e-09 36.9 0.1 3.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 OWF38517.1 - 1.8e-05 24.9 0.2 0.00064 19.9 0.2 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 OWF38517.1 - 0.00086 19.3 0.0 0.0032 17.5 0.0 2.0 1 0 0 1 1 1 1 C17orf99 Ig domain Ig_4 PF16680.5 OWF38517.1 - 0.17 12.2 2.3 1.6 9.0 0.1 3.2 2 2 1 3 3 3 0 T-cell surface glycoprotein CD3 delta chain adh_short PF00106.25 OWF38518.1 - 1.6e-36 125.6 0.0 2.8e-36 124.8 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38518.1 - 6.2e-23 81.6 0.0 9.3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38518.1 - 8.6e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 KR domain TGF_beta PF00019.20 OWF38518.1 - 0.2 12.6 0.0 0.38 11.8 0.0 1.4 1 0 0 1 1 1 0 Transforming growth factor beta like domain adh_short PF00106.25 OWF38519.1 - 4.5e-39 133.9 0.0 5.7e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38519.1 - 5.9e-28 98.0 0.0 8.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38519.1 - 0.00025 21.0 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain EF-hand_1 PF00036.32 OWF38520.1 - 1.9e-27 92.7 17.7 1.4e-07 30.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF38520.1 - 1.1e-25 89.8 4.0 2.3e-12 47.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF38520.1 - 1.3e-23 80.9 6.7 2.1e-07 30.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF38520.1 - 5.5e-22 76.2 13.4 1.3e-06 27.6 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF38520.1 - 7.6e-12 44.9 13.5 9.7e-07 28.5 0.1 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF38520.1 - 1.4e-07 31.7 0.2 8.3e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF38520.1 - 1.3e-05 25.5 0.7 0.13 12.5 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF38520.1 - 0.00013 21.9 2.1 0.23 11.4 0.3 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF38520.1 - 0.0058 16.6 1.0 0.14 12.0 1.0 2.9 1 1 0 1 1 1 1 Caleosin related protein Dockerin_1 PF00404.18 OWF38520.1 - 0.018 15.2 2.4 3.5 7.9 0.4 3.3 3 1 0 3 3 3 0 Dockerin type I domain DUF5067 PF16729.5 OWF38520.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) DUF3741 PF12552.8 OWF38520.1 - 1.3 9.1 4.4 4.8 7.2 0.7 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3741) EF-hand_7 PF13499.6 OWF38522.1 - 2.4e-09 37.5 4.9 2.4e-09 37.5 4.9 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF38522.1 - 2.1e-08 33.1 5.4 0.00068 19.0 0.6 3.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF38522.1 - 1.9e-07 30.8 5.2 2.6e-07 30.4 1.9 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF38522.1 - 7.6e-07 28.3 3.4 0.016 14.7 0.9 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF38522.1 - 2e-05 24.1 17.7 9.1e-05 22.1 0.3 4.3 4 1 1 5 5 5 2 EF-hand domain Ion_trans_2 PF07885.16 OWF38523.1 - 3.3e-35 119.9 16.9 3.9e-18 65.2 0.5 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF38523.1 - 3.5e-09 36.3 3.3 0.00032 20.0 0.0 2.3 1 1 1 2 2 2 2 Ion transport protein LPD15 PF18828.1 OWF38523.1 - 0.079 12.8 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 IRK PF01007.20 OWF38523.1 - 0.21 11.4 4.2 0.23 11.3 0.1 2.5 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF4271 PF14093.6 OWF38523.1 - 0.48 10.3 11.8 1.5 8.7 2.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) Oxidored_q2 PF00420.24 OWF38523.1 - 0.79 9.4 7.7 5.2 6.8 0.1 2.7 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2178 PF09946.9 OWF38523.1 - 2.8 8.1 5.5 13 6.0 0.2 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2178) Cornifin PF02389.15 OWF38525.1 - 4.1e-12 46.4 139.7 1.2e-06 28.7 22.2 5.2 1 1 4 5 5 5 4 Cornifin (SPRR) family Ion_trans_2 PF07885.16 OWF38527.1 - 2.4e-31 107.5 14.3 1.8e-15 56.7 7.1 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF38527.1 - 1.8e-08 34.0 4.4 0.0029 16.9 4.0 2.2 1 1 1 2 2 2 2 Ion transport protein YniB PF14002.6 OWF38527.1 - 0.026 14.3 0.7 0.24 11.2 0.0 2.5 3 0 0 3 3 3 0 YniB-like protein FAM70 PF14967.6 OWF38527.1 - 0.053 13.0 1.5 0.1 12.1 1.5 1.4 1 0 0 1 1 1 0 FAM70 protein DUF2178 PF09946.9 OWF38527.1 - 0.95 9.7 5.4 5.4 7.2 0.1 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2178) Ion_trans_2 PF07885.16 OWF38528.1 - 1.7e-31 108.0 17.7 1.5e-15 56.9 0.2 2.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF38528.1 - 2.6e-07 30.2 5.4 0.0032 16.8 4.2 2.3 1 1 1 2 2 2 2 Ion transport protein FAM70 PF14967.6 OWF38528.1 - 2.8 7.3 5.4 1 8.8 0.7 2.0 2 0 0 2 2 2 0 FAM70 protein BK_channel_a PF03493.18 OWF38529.1 - 2.4e-24 85.4 0.1 8.2e-24 83.6 0.1 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 OWF38529.1 - 3.8e-13 49.2 4.3 9.8e-13 47.9 4.3 1.7 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 OWF38529.1 - 1.6e-06 28.3 0.2 0.0044 17.3 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.31 OWF38529.1 - 0.067 12.4 11.3 0.14 11.4 11.3 1.5 1 1 0 1 1 1 0 Ion transport protein Indigoidine_A PF04227.12 OWF38530.1 - 7.9e-130 432.4 1.6 1.2e-129 431.8 1.6 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OWF38530.1 - 1.4e-33 116.5 0.0 4.6e-33 114.8 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase MFS_1 PF07690.16 OWF38531.1 - 1.3e-33 116.4 58.8 1.3e-20 73.7 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OWF38531.1 - 0.001 17.7 11.3 0.001 17.7 11.3 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein ComK PF06338.11 OWF38531.1 - 0.083 12.5 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 ComK protein SOG2 PF10428.9 OWF38534.1 - 2.1 7.4 15.6 2.6 7.2 15.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Amino_oxidase PF01593.24 OWF38535.1 - 4.5e-80 270.2 0.0 6.1e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF38535.1 - 2.7e-11 43.5 1.0 6e-11 42.4 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CW PF07496.15 OWF38535.1 - 3.9e-10 39.6 0.6 1.2e-09 38.0 0.6 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger SWIRM PF04433.17 OWF38535.1 - 1.9e-09 37.7 0.3 8e-09 35.7 0.1 2.1 2 0 0 2 2 2 1 SWIRM domain Pyr_redox PF00070.27 OWF38535.1 - 1.6e-08 35.0 0.5 9.5e-07 29.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF38535.1 - 5.1e-08 32.5 0.3 1.1e-06 28.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OWF38535.1 - 8.4e-07 28.5 0.4 1.7e-06 27.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF38535.1 - 1.6e-06 27.1 1.3 5.1e-06 25.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OWF38535.1 - 1.9e-06 27.7 3.1 6.9e-06 25.9 3.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OWF38535.1 - 1.1e-05 24.7 0.4 1.9e-05 24.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OWF38535.1 - 1.5e-05 24.3 0.1 3.4e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OWF38535.1 - 0.00015 20.9 2.4 0.00025 20.3 2.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF38535.1 - 0.00023 20.6 0.0 0.00047 19.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OWF38535.1 - 0.00026 20.3 0.6 0.0015 17.9 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF38535.1 - 0.00057 19.0 0.3 0.0014 17.7 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OWF38535.1 - 0.0018 17.7 3.5 0.0039 16.6 3.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OWF38535.1 - 0.024 14.7 0.3 0.89 9.5 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OWF38535.1 - 0.062 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 OWF38535.1 - 0.085 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain YjeF_N PF03853.15 OWF38535.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_7 PF13241.6 OWF38535.1 - 0.18 12.3 0.1 0.43 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Aldedh PF00171.22 OWF38536.1 - 4.6e-148 493.6 0.0 5.8e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glutenin_hmw PF03157.13 OWF38536.1 - 2.7e-09 36.1 11.9 4.7e-06 25.3 3.6 1.8 1 1 1 2 2 2 2 High molecular weight glutenin subunit DDE_Tnp_IS1 PF03400.13 OWF38536.1 - 9.7e-07 29.2 1.2 13 6.2 0.0 5.3 1 1 5 6 6 6 4 IS1 transposase FYVE PF01363.21 OWF38537.1 - 0.025 14.7 9.3 0.057 13.6 9.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.7 OWF38537.1 - 0.07 13.2 9.1 2.4 8.2 3.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.16 OWF38537.1 - 0.09 13.0 11.2 0.9 9.8 6.9 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger PHD PF00628.29 OWF38537.1 - 0.15 12.0 12.0 1.1 9.2 11.2 2.3 1 1 1 2 2 2 0 PHD-finger DUF4637 PF15470.6 OWF38537.1 - 0.74 9.5 9.9 2.3 7.9 3.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) IBR PF01485.21 OWF38537.1 - 4.5 7.6 12.1 0.47 10.7 6.3 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain C1_1 PF00130.22 OWF38537.1 - 7 6.6 12.3 5.5 6.9 6.9 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FAM167 PF11652.8 OWF38539.1 - 3.4e-29 101.2 1.7 3.4e-29 101.2 1.7 1.7 2 0 0 2 2 2 1 FAM167 DUF4530 PF15039.6 OWF38539.1 - 0.025 14.7 0.5 0.053 13.7 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4530) Macoilin PF09726.9 OWF38539.1 - 0.064 11.8 3.9 0.077 11.6 3.9 1.0 1 0 0 1 1 1 0 Macoilin family FAM167 PF11652.8 OWF38540.1 - 6.8e-28 97.0 2.3 6.8e-28 97.0 2.3 2.1 3 0 0 3 3 3 1 FAM167 DUF4404 PF14357.6 OWF38540.1 - 0.32 11.6 3.8 0.61 10.8 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) ACOX PF01756.19 OWF38541.1 - 9.7e-103 341.3 10.7 7.1e-56 188.6 2.7 2.9 2 1 1 3 3 3 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OWF38541.1 - 4.3e-30 104.8 0.2 1.1e-29 103.6 0.2 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OWF38541.1 - 1.7e-08 34.6 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain TAFII28 PF04719.14 OWF38541.1 - 0.0012 18.9 0.5 2.1 8.5 0.0 2.8 2 1 0 2 2 2 2 hTAFII28-like protein conserved region Peptidase_S41_N PF11918.8 OWF38541.1 - 0.0019 18.4 0.9 3 8.1 0.0 2.7 3 0 0 3 3 3 2 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Acyl-CoA_dh_1 PF00441.24 OWF38541.1 - 0.016 15.4 2.5 0.041 14.1 0.1 2.8 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DASH_Spc34 PF08657.10 OWF38541.1 - 0.063 13.1 0.1 5 6.8 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Spc34 Acyl-CoA_dh_N PF02771.16 OWF38541.1 - 0.068 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain DCB PF16213.5 OWF38541.1 - 0.11 12.1 2.8 0.39 10.3 0.4 2.8 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 FIST_C PF10442.9 OWF38541.1 - 0.17 11.9 0.0 31 4.6 0.0 2.8 2 0 0 2 2 2 0 FIST C domain CBM_5_12 PF02839.14 OWF38541.1 - 3 8.6 5.8 39 5.1 0.6 2.8 2 0 0 2 2 2 0 Carbohydrate binding domain Ku PF02735.16 OWF38542.1 - 1.5e-46 158.7 0.0 2.5e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 OWF38542.1 - 3.9e-37 127.1 2.5 3.9e-37 127.1 2.5 1.9 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 OWF38542.1 - 1.4e-25 90.4 0.0 4.3e-25 88.8 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 OWF38542.1 - 1.7e-15 57.5 1.8 1.7e-15 57.5 1.8 3.9 2 2 0 2 2 2 1 Ku70/Ku80 C-terminal arm HCMV_UL139 PF12507.8 OWF38542.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.4 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Cytomega_UL84 PF06284.11 OWF38542.1 - 2.3 6.6 4.7 12 4.2 4.6 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein Glyco_hydro_16 PF00722.21 OWF38543.1 - 4.9e-18 65.2 2.7 5e-18 65.2 0.6 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 OWF38544.1 - 2.4e-19 69.5 3.0 2.4e-19 69.5 3.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ank_2 PF12796.7 OWF38545.1 - 1.1e-14 54.8 0.0 2.1e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF38545.1 - 5e-10 38.8 0.0 0.0023 18.3 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OWF38545.1 - 6.4e-09 36.2 0.1 0.00026 21.5 0.1 2.8 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF38545.1 - 5.6e-08 32.9 0.3 1.8e-05 25.0 0.3 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OWF38545.1 - 2.2e-05 24.6 0.0 0.00058 20.1 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Mucin PF01456.17 OWF38548.1 - 0.21 11.6 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS18 PF17352.2 OWF38550.1 - 2.5 8.5 9.4 3 8.3 9.4 1.1 1 0 0 1 1 1 0 Male Flower Specific protein 18 CCSAP PF15748.5 OWF38554.1 - 3.1e-16 60.3 20.4 1e-15 58.7 20.4 1.7 1 1 0 1 1 1 1 Centriole, cilia and spindle-associated Ras PF00071.22 OWF38555.1 - 2e-58 196.5 0.1 2.4e-58 196.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF38555.1 - 3.4e-33 114.4 0.1 5.3e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF38555.1 - 3.6e-16 59.1 0.0 9.5e-16 57.7 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF38555.1 - 1e-05 25.2 0.0 0.00018 21.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF38555.1 - 1.6e-05 24.4 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF38555.1 - 0.00026 21.1 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF38555.1 - 0.0051 16.7 0.2 2.5 8.0 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OWF38555.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OWF38555.1 - 0.023 14.5 0.0 3.5 7.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 OWF38555.1 - 0.024 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Homeodomain PF00046.29 OWF38556.1 - 1.6e-22 79.1 3.4 2.9e-22 78.3 3.4 1.4 1 0 0 1 1 1 1 Homeodomain Xylo_C PF12529.8 OWF38556.1 - 0.0064 16.1 0.1 0.0091 15.6 0.1 1.2 1 0 0 1 1 1 1 Xylosyltransferase C terminal Homeobox_KN PF05920.11 OWF38556.1 - 0.36 10.8 0.0 0.36 10.8 0.0 2.6 3 1 0 3 3 3 0 Homeobox KN domain MBOAT_2 PF13813.6 OWF38557.1 - 0.027 14.7 2.0 7.8 6.8 1.2 3.2 1 1 1 2 2 2 0 Membrane bound O-acyl transferase family Mab-21 PF03281.14 OWF38558.1 - 1.3e-33 116.6 0.0 2.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Mab-21 protein TPR_7 PF13176.6 OWF38558.1 - 0.001 19.0 0.1 0.17 12.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF38558.1 - 0.001 19.7 0.1 6.3 7.9 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 OWF38558.1 - 0.078 13.3 0.0 0.59 10.5 0.0 2.5 2 0 0 2 2 2 0 PPR repeat TPR_2 PF07719.17 OWF38558.1 - 0.11 12.7 1.0 4.1 7.8 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OWF38558.1 - 0.2 12.0 6.9 5 7.6 0.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF38558.1 - 1.1 9.2 6.5 7.7 6.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Rap_GAP PF02145.15 OWF38559.1 - 3.2e-66 222.4 0.2 5.9e-66 221.6 0.2 1.5 1 0 0 1 1 1 1 Rap/ran-GAP SPAR_C PF11881.8 OWF38559.1 - 9.7e-24 84.6 3.1 9.7e-24 84.6 3.1 2.9 3 1 0 3 3 1 1 C-terminal domain of SPAR protein PDZ PF00595.24 OWF38559.1 - 9.1e-06 25.9 0.1 0.00085 19.6 0.0 2.7 2 0 0 2 2 2 1 PDZ domain DivIC PF04977.15 OWF38559.1 - 0.00042 20.0 4.7 0.00042 20.0 4.7 2.1 2 0 0 2 2 2 1 Septum formation initiator Rootletin PF15035.6 OWF38559.1 - 0.0039 17.2 3.9 0.0039 17.2 3.9 2.2 2 0 0 2 2 1 1 Ciliary rootlet component, centrosome cohesion PI3K_P85_iSH2 PF16454.5 OWF38559.1 - 0.0069 16.0 2.7 0.022 14.4 2.7 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BRE1 PF08647.11 OWF38559.1 - 0.0093 16.0 1.8 0.0093 16.0 1.8 2.4 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 OWF38559.1 - 0.01 16.3 4.0 0.037 14.6 4.0 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region PDZ_6 PF17820.1 OWF38559.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain NRBF2 PF08961.10 OWF38559.1 - 0.029 14.0 1.9 0.11 12.1 1.9 2.0 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Leu_zip PF15294.6 OWF38559.1 - 0.03 13.9 1.0 0.082 12.4 1.0 1.7 1 0 0 1 1 1 0 Leucine zipper DUF4164 PF13747.6 OWF38559.1 - 0.068 13.5 2.6 0.27 11.5 2.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 OWF38559.1 - 0.073 13.5 2.1 0.24 11.8 2.1 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 OWF38559.1 - 0.078 13.1 3.4 0.27 11.3 3.4 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 OWF38559.1 - 0.081 13.6 2.7 0.5 11.0 2.7 2.4 1 0 0 1 1 1 0 Initiation control protein YabA Troponin PF00992.20 OWF38559.1 - 0.088 13.1 2.7 0.27 11.5 2.7 1.8 1 0 0 1 1 1 0 Troponin Spc7 PF08317.11 OWF38559.1 - 0.1 11.4 4.8 0.19 10.6 4.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.8 OWF38559.1 - 0.13 11.9 6.4 0.42 10.2 6.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TMF_TATA_bd PF12325.8 OWF38559.1 - 0.14 12.4 4.2 0.46 10.7 4.2 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4518 PF15008.6 OWF38559.1 - 0.15 11.2 1.2 0.46 9.6 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Lzipper-MIP1 PF14389.6 OWF38559.1 - 0.27 11.5 5.1 1.3 9.4 5.1 2.2 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Rab5-bind PF09311.11 OWF38559.1 - 0.33 10.3 6.8 0.072 12.5 3.1 1.7 2 0 0 2 2 2 0 Rabaptin-like protein DUF724 PF05266.14 OWF38559.1 - 0.39 10.5 5.6 1.7 8.4 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) bZIP_2 PF07716.15 OWF38559.1 - 0.54 10.4 10.2 0.72 10.0 6.0 3.0 1 1 1 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 OWF38559.1 - 0.68 10.4 11.2 2.3 8.7 11.2 1.9 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 OWF38559.1 - 0.73 10.0 6.0 1.1 9.4 4.4 2.1 1 1 1 2 2 2 0 bZIP transcription factor kleA_kleC PF17383.2 OWF38559.1 - 0.92 9.9 2.6 3.4 8.1 2.6 2.0 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Taxilin PF09728.9 OWF38559.1 - 1.2 8.2 8.9 0.089 12.0 3.8 1.6 2 0 0 2 2 1 0 Myosin-like coiled-coil protein Cnn_1N PF07989.11 OWF38559.1 - 1.9 8.7 5.8 6 7.1 5.8 1.9 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 OWF38559.1 - 2.9 8.6 8.7 11 6.7 8.7 2.1 1 0 0 1 1 1 0 SlyX FPP PF05911.11 OWF38559.1 - 8.3 4.4 14.8 3.7 5.6 3.6 3.2 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil KBP_C PF12309.8 OWF38560.1 - 4.5e-116 388.3 7.7 4.5e-116 388.3 7.7 1.8 2 0 0 2 2 2 1 KIF-1 binding protein C terminal TPR_7 PF13176.6 OWF38560.1 - 2.7e-05 23.9 2.3 0.065 13.3 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF38560.1 - 7.9e-05 22.3 0.1 0.91 9.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF38560.1 - 0.00011 22.1 2.6 1.8 8.9 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF38560.1 - 0.0029 17.9 4.5 1.3 9.4 0.6 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF38560.1 - 0.0069 16.4 0.2 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OWF38560.1 - 0.046 13.6 0.8 0.98 9.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF38560.1 - 0.28 11.7 1.7 43 4.7 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF38560.1 - 0.88 10.6 3.3 29 5.9 0.0 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat NumbF PF06311.12 OWF38561.1 - 3.6e-34 117.2 1.4 2.3e-33 114.6 1.4 2.5 1 0 0 1 1 1 1 NUMB domain PID PF00640.23 OWF38561.1 - 2.4e-20 73.0 1.4 2.1e-19 69.9 1.4 2.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DLIC PF05783.11 OWF38561.1 - 2.5e-07 29.9 6.2 5.5e-06 25.5 0.1 2.6 2 1 1 3 3 3 2 Dynein light intermediate chain (DLIC) PID_2 PF14719.6 OWF38561.1 - 0.00023 21.1 0.5 0.00048 20.0 0.5 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Roc PF08477.13 OWF38561.1 - 0.00036 20.7 0.0 0.00087 19.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PTB PF08416.13 OWF38561.1 - 0.0095 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Ras PF00071.22 OWF38561.1 - 0.029 14.0 0.0 0.65 9.6 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.6 OWF38561.1 - 0.035 14.4 0.0 0.14 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OWF38561.1 - 0.093 13.1 0.1 0.3 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Transformer PF06495.11 OWF38561.1 - 9.5 6.3 11.9 0.23 11.6 4.5 2.0 2 0 0 2 2 2 0 Fruit fly transformer protein TMEM154 PF15102.6 OWF38562.1 - 0.13 12.1 0.1 0.13 12.1 0.1 7.6 2 1 0 2 2 2 0 TMEM154 protein family DUF3377 PF11857.8 OWF38562.1 - 4.9 7.2 4.9 2.1 8.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DNA_pol_E_B PF04042.16 OWF38563.1 - 2.9e-52 177.1 0.7 4.1e-52 176.6 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 OWF38563.1 - 1.4e-28 99.0 0.3 3.4e-28 97.8 0.3 1.7 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Symplekin_C PF12295.8 OWF38563.1 - 0.052 13.6 0.2 4 7.5 0.0 2.8 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal Peptidase_M16 PF00675.20 OWF38563.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) KRE9 PF05390.11 OWF38564.1 - 4.6 8.0 214.9 44 4.9 1.1 29.5 1 1 56 57 57 57 0 Yeast cell wall synthesis protein KRE9/KNH1 L_HMGIC_fpl PF10242.9 OWF38565.1 - 0.0031 17.7 5.0 0.0031 17.7 5.0 1.9 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein TatC PF00902.18 OWF38565.1 - 0.0093 15.8 9.2 0.025 14.4 9.3 1.6 1 1 1 2 2 2 1 Sec-independent protein translocase protein (TatC) SecD_SecF PF02355.16 OWF38565.1 - 0.031 13.7 4.8 0.049 13.0 4.8 1.3 1 0 0 1 1 1 0 Protein export membrane protein DUF2070 PF09843.9 OWF38565.1 - 0.33 9.2 4.3 0.31 9.3 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Claudin_3 PF06653.11 OWF38565.1 - 0.58 10.1 18.2 22 4.9 18.2 2.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Adap_comp_sub PF00928.21 OWF38566.1 - 1.1e-18 67.5 0.0 1.3e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family KH_1 PF00013.29 OWF38567.1 - 4.6e-07 29.6 0.0 9.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 OWF38567.1 - 0.00033 20.4 2.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 Qua1 domain Orn_Arg_deC_N PF02784.16 OWF38568.1 - 1e-81 274.0 0.0 1.3e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF38568.1 - 1.6e-18 66.7 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OWF38568.1 - 3.6e-05 23.3 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Plant_tran PF04827.14 OWF38568.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein zf-C2H2 PF00096.26 OWF38569.1 - 3e-13 49.4 23.2 5.1e-05 23.5 3.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF38569.1 - 5.3e-12 45.6 7.5 1.1e-06 28.7 0.9 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF38569.1 - 4e-08 33.4 18.8 0.00077 20.1 2.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 OWF38569.1 - 0.0044 17.4 12.3 0.1 13.1 1.9 4.0 3 1 0 3 3 3 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OWF38569.1 - 0.17 12.5 6.7 2.7 8.7 0.3 3.0 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 OWF38569.1 - 0.88 9.6 5.7 0.34 11.0 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF38569.1 - 1.4 9.3 13.0 2.6 8.4 0.8 3.6 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LRR_8 PF13855.6 OWF38570.1 - 1.3e-19 69.7 15.5 9.1e-09 35.0 3.5 4.4 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OWF38570.1 - 1.4e-14 53.9 19.8 0.00018 21.8 0.6 5.4 2 1 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF38570.1 - 0.00031 20.9 20.0 7.7 7.5 0.1 8.1 7 2 1 8 8 8 1 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 OWF38570.1 - 0.014 15.4 0.3 6.8 6.8 0.0 3.7 4 1 1 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain LRR_9 PF14580.6 OWF38570.1 - 0.046 13.2 5.1 1.3 8.5 0.6 2.6 1 1 2 3 3 3 0 Leucine-rich repeat MFMR_assoc PF16596.5 OWF38570.1 - 3.5 8.1 10.0 4.9 7.6 10.0 1.1 1 0 0 1 1 1 0 Disordered region downstream of MFMR OCC1 PF15506.6 OWF38571.1 - 6.9 6.9 10.8 0.51 10.5 0.3 2.7 2 1 1 3 3 3 0 OCC1 family Aminotran_MocR PF12897.7 OWF38572.1 - 0.018 13.9 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 OWF38572.1 - 0.018 14.2 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_1_2 PF00155.21 OWF38573.1 - 4.3e-19 68.9 0.0 5.2e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OWF38573.1 - 2.1e-12 46.6 0.0 2.6e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase RNB PF00773.19 OWF38574.1 - 3.2e-58 197.6 0.1 6e-58 196.7 0.1 1.5 1 0 0 1 1 1 1 RNB domain AAA_12 PF13087.6 OWF38574.1 - 3.3e-47 160.7 0.2 7.2e-47 159.6 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OWF38574.1 - 6.6e-42 144.1 0.3 8.3e-40 137.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF38574.1 - 4.9e-11 42.7 0.0 5.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OWF38574.1 - 1.2e-07 32.2 0.0 7.5e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF38574.1 - 5.5e-05 23.5 0.0 0.0038 17.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OWF38574.1 - 8.5e-05 22.4 0.6 0.17 11.6 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 OWF38574.1 - 9e-05 22.0 1.6 0.001 18.5 0.1 2.3 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 OWF38574.1 - 0.0011 18.8 0.1 0.0081 16.0 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 OWF38574.1 - 0.0012 18.8 0.3 0.013 15.5 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OWF38574.1 - 0.0038 16.5 0.1 0.47 9.6 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) OB_Dis3 PF17849.1 OWF38574.1 - 0.011 15.7 0.2 0.23 11.5 0.2 2.6 1 1 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) DUF4346 PF14251.6 OWF38574.1 - 0.085 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) PhoH PF02562.16 OWF38574.1 - 0.087 12.3 0.1 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF3501 PF12007.8 OWF38574.1 - 0.19 11.7 3.4 0.56 10.2 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3501) Clathrin PF00637.20 OWF38575.1 - 4.2e-13 49.4 33.3 0.086 12.7 0.1 10.7 7 2 3 11 11 11 5 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 OWF38575.1 - 1.2e-07 31.9 0.7 0.18 12.1 0.2 5.4 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF38575.1 - 8.1e-05 23.3 6.4 39 5.3 0.1 6.9 7 0 0 7 7 6 0 WD domain, G-beta repeat TPR_7 PF13176.6 OWF38575.1 - 0.004 17.1 24.9 2.3 8.4 0.0 10.2 11 2 1 12 12 11 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 OWF38575.1 - 0.0043 16.2 0.0 0.0043 16.2 0.0 3.8 4 1 1 5 5 5 1 Coatomer WD associated region HHH_4 PF14490.6 OWF38575.1 - 0.03 14.3 0.3 0.52 10.3 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain ERCC4 PF02732.15 OWF38575.1 - 0.091 13.0 0.1 7.7 6.7 0.1 2.6 2 0 0 2 2 2 0 ERCC4 domain Sec16_C PF12931.7 OWF38575.1 - 0.14 11.8 5.7 0.26 10.9 0.3 3.2 2 2 1 3 3 3 0 Sec23-binding domain of Sec16 TPR_11 PF13414.6 OWF38575.1 - 0.18 11.5 1.3 38 4.1 0.0 4.4 3 0 0 3 3 3 0 TPR repeat CdiI_2 PF18593.1 OWF38575.1 - 0.63 10.7 3.0 21 5.9 0.1 4.4 4 0 0 4 4 3 0 CdiI immunity protein TPR_2 PF07719.17 OWF38575.1 - 3.3 8.1 42.3 5.2 7.4 0.0 12.5 13 1 0 14 14 12 0 Tetratricopeptide repeat MatP PF06303.12 OWF38575.1 - 4.2 8.0 5.5 3.3 8.3 0.3 3.6 3 0 0 3 3 3 0 MatP N-terminal domain TPR_16 PF13432.6 OWF38575.1 - 7.3 7.3 26.7 1.5 9.5 0.5 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF38575.1 - 8.5 6.7 17.5 12 6.2 0.4 7.7 7 2 2 9 9 9 0 Anaphase-promoting complex, cyclosome, subunit 3 ASFV_J13L PF05568.11 OWF38576.1 - 4e-21 75.6 41.9 0.032 14.0 1.4 8.8 1 1 8 9 9 9 9 African swine fever virus J13L protein Innate_immun PF12782.7 OWF38576.1 - 8.5e-06 25.5 44.2 0.09 12.3 2.7 5.2 1 1 3 4 4 4 3 Invertebrate innate immunity transcript family AhpC-TSA_2 PF13911.6 OWF38577.1 - 2e-18 66.5 0.0 3.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OWF38577.1 - 5.2e-10 39.3 0.1 7.8e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OWF38577.1 - 5.1e-07 29.5 0.0 7.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 OWF38577.1 - 0.00039 20.0 0.0 0.00066 19.3 0.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Glycos_transf_1 PF00534.20 OWF38577.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF1473 PF07341.11 OWF38577.1 - 0.042 13.6 1.0 0.091 12.5 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1473) AhpC-TSA_2 PF13911.6 OWF38578.1 - 3e-17 62.8 0.0 4.4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 OWF38578.1 - 6.2e-10 39.1 0.0 8.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OWF38578.1 - 7.4e-06 25.7 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 OWF38578.1 - 0.0056 16.2 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Ldl_recept_a PF00057.18 OWF38579.1 - 1.2e-73 243.0 177.0 9.7e-12 44.9 16.2 9.6 10 0 0 10 10 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 OWF38579.1 - 1.8e-41 140.4 7.1 2.4e-11 43.9 0.0 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 OWF38579.1 - 3.9e-11 43.0 39.5 5.8e-08 32.9 11.0 8.8 5 3 3 8 8 5 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF38579.1 - 2e-05 24.4 30.8 0.00091 19.1 2.1 5.6 4 0 0 4 4 3 3 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF38579.1 - 4.9e-05 23.5 9.0 4.9e-05 23.5 9.0 12.7 4 3 5 9 9 5 1 Calcium-binding EGF domain DUF5050 PF16472.5 OWF38579.1 - 0.004 16.5 0.1 0.024 13.9 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF5050) Arylesterase PF01731.20 OWF38579.1 - 0.0048 17.1 0.0 2.7 8.2 0.0 3.8 3 1 1 4 4 4 1 Arylesterase PTP_tm PF18861.1 OWF38579.1 - 0.022 14.8 3.6 0.047 13.7 3.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 OWF38579.1 - 0.16 12.9 0.0 0.44 11.5 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 OWF38579.1 - 0.23 11.5 5.7 0.55 10.3 5.7 1.6 1 0 0 1 1 1 0 Podoplanin IgaA PF07095.11 OWF38579.1 - 0.24 9.4 0.0 0.34 8.8 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF1035 PF06281.12 OWF38579.1 - 0.62 10.1 4.1 1.3 9.1 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) TMEM154 PF15102.6 OWF38579.1 - 2.9 7.8 8.2 29 4.6 8.2 2.3 1 1 0 1 1 1 0 TMEM154 protein family Amdo_NSP PF12475.8 OWF38580.1 - 0.00089 19.3 5.9 3e+02 1.6 0.1 12.0 4 0 0 4 4 4 0 Amdovirus non-structural protein MOZART1 PF12554.8 OWF38580.1 - 0.0056 16.4 62.2 36 4.2 0.1 24.2 2 1 64 66 66 66 2 Mitotic-spindle organizing gamma-tubulin ring associated MFS_1 PF07690.16 OWF38582.1 - 3.7e-48 164.3 45.8 3.3e-46 157.8 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 OWF38582.1 - 4.3 7.7 6.8 4.4 7.6 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Sod_Cu PF00080.20 OWF38583.1 - 1.1e-28 100.2 3.2 2.1e-28 99.3 0.0 2.4 2 1 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.25 OWF38584.1 - 1.5e-60 204.8 0.0 1.5e-60 204.8 0.0 3.9 5 2 1 6 6 6 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38584.1 - 5.1e-30 104.6 1.2 7e-29 100.9 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.11 OWF38584.1 - 9.2e-13 48.8 15.7 9.2e-13 48.8 15.7 11.6 9 4 4 13 13 13 1 Rho Binding PH PF00169.29 OWF38584.1 - 4.2e-06 27.2 0.7 0.0029 18.1 0.0 3.5 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 OWF38584.1 - 1.2e-05 25.1 5.9 2.4e-05 24.1 5.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_11 PF15413.6 OWF38584.1 - 0.014 15.8 0.1 0.014 15.8 0.1 4.2 4 0 0 4 4 4 0 Pleckstrin homology domain APH PF01636.23 OWF38584.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 OWF38584.1 - 0.19 12.4 1.1 0.65 10.7 1.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain AKAP7_NLS PF10469.9 OWF38585.1 - 5.1e-32 111.5 1.4 1.3e-31 110.1 1.4 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 OWF38585.1 - 5.8e-10 39.3 0.0 7.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.9 OWF38586.1 - 2.2e-40 138.7 0.1 3.4e-40 138.2 0.1 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 OWF38586.1 - 4.6e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DUF5523 PF17661.1 OWF38587.1 - 2.5e-54 184.6 27.3 2.5e-54 184.6 27.3 5.7 3 1 1 5 5 5 1 Family of unknown function (DUF5523) CC2D2AN-C2 PF15625.6 OWF38587.1 - 3.9e-53 179.7 0.2 1e-52 178.3 0.2 1.8 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain Tcp10_C PF07202.13 OWF38589.1 - 0.08 12.9 29.8 8.7 6.3 0.7 6.7 1 1 10 11 11 11 0 T-complex protein 10 C-terminus HAT_KAT11 PF08214.11 OWF38589.1 - 2.3 7.4 97.3 3.3 6.9 0.9 19.0 1 1 12 13 13 13 0 Histone acetylation protein TGF_beta PF00019.20 OWF38590.1 - 7.3e-25 87.9 0.8 2.4e-24 86.3 0.8 1.9 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 OWF38590.1 - 6.5e-13 49.0 4.7 1e-12 48.4 4.7 1.3 1 0 0 1 1 1 1 TGF-beta propeptide Tlr3_TMD PF17968.1 OWF38590.1 - 2.7 8.2 4.2 5.3 7.3 4.2 1.4 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain DcpS_C PF11969.8 OWF38591.1 - 1.6e-33 115.6 0.2 1.9e-33 115.3 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OWF38591.1 - 3.7e-09 37.2 5.4 1.6e-08 35.2 5.4 1.8 1 1 0 1 1 1 1 HIT domain PAP2 PF01569.21 OWF38592.1 - 1.1e-26 93.2 5.0 1.1e-26 93.2 5.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OWF38592.1 - 1.8e-05 24.5 5.3 3.9e-05 23.4 5.2 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OWF38592.1 - 0.0046 17.5 7.3 0.0046 17.5 7.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily C-terminal Colicin_V PF02674.16 OWF38592.1 - 0.13 12.2 5.6 0.14 12.1 0.9 2.5 2 1 0 2 2 2 0 Colicin V production protein Pet100 PF09803.9 OWF38593.1 - 7.7e-05 23.1 0.3 9e-05 22.9 0.3 1.3 1 1 0 1 1 1 1 Pet100 Fer4_20 PF14691.6 OWF38594.1 - 0.081 12.7 0.6 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster HMG_box PF00505.19 OWF38595.1 - 8.8e-25 86.9 1.0 1.8e-24 85.9 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF38595.1 - 3e-11 43.7 0.6 7.7e-11 42.4 0.6 1.7 1 0 0 1 1 1 1 HMG-box domain DUF3802 PF12290.8 OWF38595.1 - 0.098 13.2 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) SVWC PF15430.6 OWF38596.1 - 4.6e-05 23.6 5.7 4.6e-05 23.6 5.7 2.1 2 1 0 2 2 2 1 Single domain von Willebrand factor type C ShK PF01549.24 OWF38596.1 - 0.0093 16.5 7.1 0.0093 16.5 7.1 3.2 4 2 0 4 4 4 1 ShK domain-like Solute_trans_a PF03619.16 OWF38597.1 - 4.2e-42 144.5 15.3 5.3e-42 144.2 15.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Gal-3-0_sulfotr PF06990.11 OWF38598.1 - 6.3e-51 173.5 2.9 8.2e-51 173.1 2.9 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF38598.1 - 0.00091 19.2 0.1 0.0054 16.7 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 OWF38599.1 - 1.4e-52 178.9 2.3 1.7e-52 178.7 2.3 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF38599.1 - 0.0003 20.8 1.0 0.0007 19.6 0.2 1.9 2 0 0 2 2 2 1 Sulfotransferase family DUF3797 PF12677.7 OWF38600.1 - 0.029 14.3 0.1 11 5.9 0.0 3.6 1 1 4 5 5 5 0 Domain of unknown function (DUF3797) NAPRTase_N PF17767.1 OWF38600.1 - 0.031 14.7 0.0 0.053 13.9 0.0 1.5 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain p47_phox_C PF08944.11 OWF38600.1 - 0.93 9.0 6.4 17 4.9 0.1 3.9 4 2 0 5 5 5 0 NADPH oxidase subunit p47Phox, C terminal domain PPI_Ypi1 PF07491.11 OWF38600.1 - 5.5 6.9 34.8 16 5.4 0.7 7.1 1 1 5 6 6 6 0 Protein phosphatase inhibitor Kelch_2 PF07646.15 OWF38600.1 - 7.8 6.6 25.8 9.2 6.4 0.6 4.3 1 1 3 4 4 4 0 Kelch motif HTH_31 PF13560.6 OWF38600.1 - 7.9 6.9 16.7 22 5.5 1.2 4.3 1 1 3 4 4 4 0 Helix-turn-helix domain Pkinase PF00069.25 OWF38601.1 - 3.2e-72 243.1 0.1 6.8e-72 242.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38601.1 - 3.7e-40 137.8 0.0 1.6e-39 135.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 OWF38601.1 - 3.3e-38 129.7 0.4 3.1e-20 72.1 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 OWF38601.1 - 1.2e-06 27.6 0.2 4.9e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OWF38601.1 - 7.9e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like LETM1 PF07766.13 OWF38601.1 - 0.028 13.8 0.8 0.043 13.2 0.8 1.2 1 0 0 1 1 1 0 LETM1-like protein DUF4524 PF15025.6 OWF38601.1 - 0.072 12.8 0.0 0.86 9.3 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4524) APH PF01636.23 OWF38601.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family cNMP_binding PF00027.29 OWF38602.1 - 8.5e-20 70.6 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OWF38602.1 - 1.2e-13 50.8 9.2 1.8e-13 50.3 9.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF38602.1 - 0.0059 16.5 4.7 0.023 14.6 4.7 2.1 1 1 0 1 1 1 1 Ion channel Pepsin-I3 PF06394.13 OWF38602.1 - 0.14 12.4 1.3 5.3 7.3 0.4 2.5 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain FAP206 PF12018.8 OWF38602.1 - 0.26 10.8 3.4 2.1 7.8 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function Glutaredoxin PF00462.24 OWF38603.1 - 5.3e-20 71.4 0.0 9.7e-20 70.6 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin Ank_5 PF13857.6 OWF38604.1 - 3.2e-26 91.0 1.3 2.7e-07 30.7 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF38604.1 - 3.5e-23 82.0 0.2 2.4e-14 53.7 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF38604.1 - 6.8e-20 70.6 8.6 1.3e-05 25.4 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 OWF38604.1 - 3.5e-17 60.7 0.0 0.00021 21.5 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OWF38604.1 - 2.8e-16 59.6 0.1 0.00025 21.5 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Glyco_hydro_20 PF00728.22 OWF38604.1 - 0.079 12.3 0.0 0.26 10.6 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain EAP30 PF04157.16 OWF38604.1 - 0.17 11.1 0.1 0.48 9.7 0.1 1.8 1 0 0 1 1 1 0 EAP30/Vps36 family UPF0020 PF01170.18 OWF38605.1 - 4.2e-19 69.0 0.0 2.4e-18 66.6 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 OWF38605.1 - 1.9e-13 50.5 0.0 4.4e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF38605.1 - 2.9e-10 40.7 0.0 7.8e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF38605.1 - 1.5e-08 35.2 0.0 3.5e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain THUMP PF02926.17 OWF38605.1 - 9.8e-06 25.7 0.0 2.9e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 THUMP domain Ubie_methyltran PF01209.18 OWF38605.1 - 1.1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 OWF38605.1 - 1.7e-05 24.3 0.0 0.0015 18.0 0.0 2.6 2 1 1 3 3 3 1 Putative methyltransferase N6_N4_Mtase PF01555.18 OWF38605.1 - 0.00069 19.4 0.0 0.67 9.6 0.0 2.4 2 0 0 2 2 2 2 DNA methylase Methyltransf_12 PF08242.12 OWF38605.1 - 0.0015 19.2 0.0 0.24 12.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OWF38605.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 OWF38605.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_33 PF10017.9 OWF38605.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Pellino PF04710.14 OWF38607.1 - 1.4e-200 666.3 0.0 1.6e-200 666.1 0.0 1.0 1 0 0 1 1 1 1 Pellino zf-RING_5 PF14634.6 OWF38607.1 - 0.026 14.5 7.0 0.089 12.8 0.1 2.8 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF38607.1 - 0.039 13.8 11.0 0.11 12.4 0.2 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 OWF38607.1 - 0.069 13.4 4.3 3.3 8.1 0.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.6 OWF38607.1 - 1 9.8 11.6 0.53 10.7 0.3 2.7 3 0 0 3 3 3 0 Ring finger domain PKcGMP_CC PF16808.5 OWF38608.1 - 0.00029 20.6 0.3 0.00029 20.6 0.3 17.3 21 0 0 21 21 21 5 Coiled-coil N-terminus of cGMP-dependent protein kinase CENP-F_leu_zip PF10473.9 OWF38608.1 - 0.0019 18.2 12.4 0.0019 18.2 12.4 20.4 4 3 17 22 22 22 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 OWF38608.1 - 0.0031 17.7 15.0 0.0031 17.7 15.0 19.7 2 2 15 20 20 20 1 Tropomyosin like GRIP PF01465.20 OWF38608.1 - 0.0094 15.8 0.0 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 GRIP domain DUF2477 PF10631.9 OWF38608.1 - 4 8.1 5.0 36 5.0 0.1 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) LRR_8 PF13855.6 OWF38609.1 - 1.2e-07 31.4 7.6 9.6e-05 22.1 0.1 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF38609.1 - 2.3e-05 24.7 3.0 0.0038 17.6 0.3 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) V-SNARE PF05008.15 OWF38610.1 - 8.3e-15 54.9 1.0 8.3e-15 54.9 1.0 2.0 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OWF38610.1 - 3.6e-13 49.6 2.5 3.6e-13 49.6 2.5 2.4 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OWF38610.1 - 8.5e-05 22.4 1.1 0.00034 20.5 1.1 2.0 1 1 0 1 1 1 1 Sec20 Fusion_gly PF00523.18 OWF38610.1 - 0.041 12.1 0.1 0.06 11.6 0.1 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF3958 PF13125.6 OWF38610.1 - 2.3 8.5 5.4 3.1 8.0 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3958) Plasmid_RAQPRD PF09686.10 OWF38610.1 - 3.6 7.9 6.1 18 5.6 0.2 3.8 4 1 1 5 5 5 0 Plasmid protein of unknown function (Plasmid_RAQPRD) FYVE PF01363.21 OWF38611.1 - 3.7e-26 91.1 26.2 1.7e-14 53.7 7.4 5.7 4 1 1 5 5 5 2 FYVE zinc finger GBP PF02263.19 OWF38611.1 - 0.00039 19.8 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Plus-3 PF03126.18 OWF38612.1 - 1.8e-33 115.3 0.1 1.8e-33 115.3 0.1 2.4 3 0 0 3 3 3 1 Plus-3 domain BAF PF02961.14 OWF38613.1 - 2.7e-44 149.5 0.2 3e-44 149.4 0.2 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor PH PF00169.29 OWF38614.1 - 5.2e-12 46.2 1.7 1.2e-11 45.1 0.2 2.5 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 OWF38614.1 - 0.0023 18.3 0.1 0.0023 18.3 0.1 3.2 2 2 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 OWF38614.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 2.9 2 1 1 3 3 3 1 Pleckstrin homology domain ERM PF00769.19 OWF38614.1 - 1.9 8.3 58.0 4.6 7.0 31.9 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nuc_sug_transp PF04142.15 OWF38615.1 - 1.1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OWF38615.1 - 4.2e-07 30.2 11.8 1.9e-06 28.1 0.2 3.0 2 2 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 OWF38615.1 - 5.8e-06 25.9 2.1 9.4e-06 25.2 2.1 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 OWF38615.1 - 1e-05 24.9 1.1 2.4e-05 23.7 0.3 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 OWF38615.1 - 4.9e-05 23.0 6.6 0.0015 18.1 8.5 2.4 2 1 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 OWF38615.1 - 0.0012 17.9 12.7 0.0012 17.9 12.7 2.2 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like CCSMST1 PF15013.6 OWF38615.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 CCSMST1 family p53-inducible11 PF14936.6 OWF38615.1 - 0.76 9.8 4.5 0.6 10.1 0.9 2.4 2 1 1 3 3 3 0 Tumour protein p53-inducible protein 11 MIase PF02426.16 OWF38616.1 - 3e-06 27.3 0.0 0.083 13.1 0.0 2.1 2 0 0 2 2 2 2 Muconolactone delta-isomerase MIase PF02426.16 OWF38617.1 - 1.7e-06 28.1 0.0 0.017 15.3 0.0 2.2 2 0 0 2 2 2 2 Muconolactone delta-isomerase UTP25 PF06862.12 OWF38618.1 - 2.9e-180 600.1 6.9 4.4e-180 599.5 6.9 1.3 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 OWF38618.1 - 0.0037 17.1 0.0 0.93 9.2 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase CDC27 PF09507.10 OWF38618.1 - 0.062 12.7 34.6 0.096 12.1 34.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRM_1 PF00076.22 OWF38619.1 - 3.5e-12 45.9 0.0 5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF38619.1 - 0.0027 17.3 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OWF38619.1 - 8.5 7.0 16.1 20 5.8 16.1 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 APG6_N PF17675.1 OWF38620.1 - 0.0013 19.3 26.0 0.13 12.8 12.2 2.7 1 1 1 2 2 2 2 Apg6 coiled-coil region Atg14 PF10186.9 OWF38620.1 - 0.0031 16.7 8.1 0.0031 16.7 8.1 2.1 1 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 OWF38620.1 - 0.012 16.3 19.3 0.022 15.4 3.8 3.4 1 1 2 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OWF38620.1 - 0.02 14.9 32.5 0.13 12.3 24.0 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-18_N PF10496.9 OWF38620.1 - 0.026 14.8 0.3 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4686 PF15742.5 OWF38620.1 - 0.039 13.1 21.7 0.086 12.0 21.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) HALZ PF02183.18 OWF38620.1 - 0.049 13.9 1.1 0.049 13.9 1.1 5.2 6 0 0 6 6 6 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 OWF38620.1 - 0.12 12.8 6.3 0.84 10.1 0.2 3.5 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KASH_CCD PF14662.6 OWF38620.1 - 0.15 11.8 28.2 0.15 11.9 2.3 2.8 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Late_protein_L2 PF00513.18 OWF38620.1 - 0.17 10.9 1.4 0.26 10.3 1.4 1.2 1 0 0 1 1 1 0 Late Protein L2 HMMR_N PF15905.5 OWF38620.1 - 0.24 10.8 19.9 0.055 12.9 16.3 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FapA PF03961.13 OWF38620.1 - 0.92 8.0 11.4 4.5 5.8 0.0 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 OWF38620.1 - 0.93 9.5 14.1 0.95 9.5 0.7 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 OWF38620.1 - 1.2 9.3 25.0 0.99 9.6 11.4 3.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 OWF38620.1 - 2.4 7.5 24.3 0.5 9.7 6.7 2.7 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 OWF38620.1 - 3.2 7.9 23.0 0.55 10.4 4.4 5.1 2 1 3 5 5 5 0 bZIP transcription factor ADIP PF11559.8 OWF38620.1 - 3.7 7.6 21.5 0.15 12.2 1.9 3.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 OWF38620.1 - 5.7 6.6 24.2 0.56 9.9 8.1 2.6 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 OWF38620.1 - 7.6 6.6 23.6 2.2 8.3 2.8 2.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OWF38620.1 - 8.5 6.8 22.2 8.1 6.9 19.7 2.0 1 1 1 2 2 2 0 Fez1 Rootletin PF15035.6 OWF38620.1 - 9 6.3 27.7 2.8 7.9 22.2 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion PAXX PF15384.6 OWF38621.1 - 1.7e-19 70.3 0.1 2e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 TPD52 PF04201.15 OWF38621.1 - 0.0036 16.9 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Tumour protein D52 family DUF1818 PF08848.11 OWF38621.1 - 0.086 12.9 0.2 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) EF-hand_7 PF13499.6 OWF38622.1 - 2.7e-14 53.3 0.8 1.2e-07 32.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF38622.1 - 9.9e-12 43.8 0.6 0.00029 20.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OWF38622.1 - 1.5e-08 33.6 1.1 0.0027 17.1 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OWF38622.1 - 4.6e-06 26.8 0.2 0.045 14.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OWF38622.1 - 4.1e-05 23.3 2.1 0.00026 20.8 0.0 3.0 3 1 1 4 4 4 1 EF-hand domain pair EFhand_Ca_insen PF08726.10 OWF38622.1 - 0.00032 20.7 0.5 0.00071 19.6 0.5 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 OWF38622.1 - 0.13 11.8 0.7 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 EF hand IMUP PF15761.5 OWF38623.1 - 0.47 11.2 6.2 0.59 10.8 6.2 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein 7TM_GPCR_Srw PF10324.9 OWF38625.1 - 2.3e-20 73.1 23.4 3e-20 72.8 23.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF38625.1 - 1e-12 48.0 23.1 1e-12 48.0 23.1 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Phage_Coat_B PF05356.11 OWF38625.1 - 0.043 13.7 0.1 0.095 12.6 0.1 1.5 1 0 0 1 1 1 0 Phage Coat protein B TMEM154 PF15102.6 OWF38625.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.3 3 1 1 4 4 4 0 TMEM154 protein family TPR_2 PF07719.17 OWF38627.1 - 2.4e-28 95.9 0.7 0.00035 20.5 0.0 8.4 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF38627.1 - 7.1e-27 92.1 1.3 0.00057 19.6 0.0 7.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 OWF38627.1 - 3.6e-22 77.8 0.0 3.4e-07 29.8 0.0 5.1 4 1 1 5 5 5 4 TPR repeat TPR_17 PF13431.6 OWF38627.1 - 6e-18 63.9 1.4 0.1 13.1 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF38627.1 - 6.8e-18 63.3 0.8 0.003 17.7 0.0 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF38627.1 - 1.4e-17 63.9 0.1 0.00039 20.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF38627.1 - 6.6e-16 57.7 0.0 0.0034 18.1 0.0 5.7 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF38627.1 - 8.3e-16 58.4 0.0 0.0021 18.7 0.0 4.4 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF38627.1 - 1.5e-13 50.8 0.6 0.039 14.2 0.0 5.7 1 1 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF38627.1 - 2.1e-11 43.9 1.4 0.0033 17.6 0.1 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OWF38627.1 - 9.9e-10 38.4 0.4 0.29 11.8 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF38627.1 - 1.8e-07 31.2 0.0 0.07 13.3 0.0 4.9 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 OWF38627.1 - 3.4e-06 27.3 0.3 0.52 10.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF38627.1 - 7.5e-05 22.5 2.0 16 5.5 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF38627.1 - 0.0029 17.5 0.3 51 4.2 0.0 6.0 7 1 0 7 7 7 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 OWF38627.1 - 0.0089 16.1 0.1 15 5.8 0.0 3.3 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region NARP1 PF12569.8 OWF38627.1 - 0.0092 14.9 0.7 2 7.2 0.0 3.1 1 1 3 4 4 4 2 NMDA receptor-regulated protein 1 PC_rep PF01851.22 OWF38627.1 - 0.013 15.9 0.0 0.08 13.4 0.1 2.2 2 0 0 2 2 2 0 Proteasome/cyclosome repeat TPR_21 PF09976.9 OWF38627.1 - 0.03 14.0 0.1 0.96 9.1 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 OWF38627.1 - 0.11 12.2 0.0 6.1 6.5 0.0 3.1 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF220 PF02713.14 OWF38627.1 - 0.14 12.2 0.1 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF220 Tetraspanin PF00335.20 OWF38628.1 - 2.4e-21 76.5 9.0 3.7e-21 75.9 9.0 1.1 1 0 0 1 1 1 1 Tetraspanin family YndJ PF14158.6 OWF38628.1 - 0.051 12.9 0.4 0.093 12.0 0.4 1.3 1 0 0 1 1 1 0 YndJ-like protein Sushi PF00084.20 OWF38629.1 - 8.1e-20 71.2 28.3 7.1e-05 23.3 0.1 5.7 5 0 0 5 5 5 5 Sushi repeat (SCR repeat) SKG6 PF08693.10 OWF38629.1 - 0.013 14.9 0.1 0.031 13.7 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ald_Xan_dh_C2 PF02738.18 OWF38629.1 - 0.059 11.8 0.2 0.098 11.1 0.2 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Plasmod_Pvs28 PF06247.11 OWF38629.1 - 0.08 13.3 0.4 5.3 7.4 0.0 3.2 3 0 0 3 3 3 0 Pvs28 EGF domain cEGF PF12662.7 OWF38629.1 - 0.2 11.6 7.1 0.5 10.3 0.5 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like DUF3377 PF11857.8 OWF38629.1 - 0.65 10.0 0.0 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) FXa_inhibition PF14670.6 OWF38629.1 - 4.7 7.6 12.1 1.3 9.3 5.1 3.3 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Glyco_transf_49 PF13896.6 OWF38630.1 - 4.3e-101 338.6 1.1 6.1e-101 338.1 1.1 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 OWF38630.1 - 0.0094 15.8 0.0 0.075 12.8 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 RA PF00788.23 OWF38630.1 - 0.037 14.7 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain SHR3_chaperone PF08229.11 OWF38630.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 SANTA PF09133.10 OWF38630.1 - 0.082 13.4 1.1 0.23 11.9 0.1 2.2 2 0 0 2 2 2 0 SANTA (SANT Associated) Ac76 PF05814.11 OWF38630.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) HEAT PF02985.22 OWF38631.1 - 1e-10 40.9 0.1 0.015 15.5 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.25 OWF38631.1 - 1.7e-09 37.5 0.0 3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38631.1 - 7.7e-09 35.2 0.0 1.9e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT_EZ PF13513.6 OWF38631.1 - 2.7e-07 30.9 0.1 0.00026 21.4 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 OWF38631.1 - 5.1e-05 23.4 0.0 0.014 15.5 0.0 2.8 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OWF38631.1 - 0.00052 20.3 0.0 0.009 16.4 0.0 2.6 1 1 2 3 3 3 1 HEAT repeats Vac14_Fab1_bd PF12755.7 OWF38631.1 - 0.018 15.6 0.1 11 6.7 0.0 3.0 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Kinase-like PF14531.6 OWF38631.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Trypan_PARP PF05887.11 OWF38631.1 - 9.3 6.2 13.0 5.8 6.9 7.4 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Inositol_P PF00459.25 OWF38632.1 - 4.5e-55 187.1 0.0 6.3e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family zf-C3HC4_3 PF13920.6 OWF38633.1 - 7.3e-05 22.5 7.5 7.3e-05 22.5 7.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF38633.1 - 0.00065 19.5 5.9 0.00065 19.5 5.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF38633.1 - 0.0017 18.3 6.3 0.0065 16.4 6.3 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF38633.1 - 0.007 16.2 7.7 0.019 14.8 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF38633.1 - 0.012 16.0 7.1 0.012 16.0 7.1 2.2 2 1 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 OWF38633.1 - 0.015 15.3 2.4 0.015 15.3 2.4 2.3 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF38633.1 - 0.024 14.5 4.8 0.024 14.5 4.8 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OWF38633.1 - 1.1 9.4 6.4 0.56 10.3 1.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger GAS PF13851.6 OWF38634.1 - 0.012 15.0 5.1 0.02 14.2 5.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 OWF38634.1 - 0.017 13.8 2.3 0.024 13.3 2.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A KxDL PF10241.9 OWF38634.1 - 0.069 13.4 0.2 0.069 13.4 0.2 3.3 1 1 1 3 3 3 0 Uncharacterized conserved protein Uds1 PF15456.6 OWF38634.1 - 0.08 13.1 1.2 0.17 12.1 1.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Leu_zip PF15294.6 OWF38634.1 - 0.11 11.9 6.0 0.19 11.2 6.0 1.3 1 0 0 1 1 1 0 Leucine zipper Spc7 PF08317.11 OWF38634.1 - 0.13 11.1 4.2 0.2 10.5 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF848 PF05852.11 OWF38634.1 - 0.16 12.1 1.2 0.31 11.1 1.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4709 PF15821.5 OWF38634.1 - 0.62 10.4 6.0 1.4 9.2 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) BLOC1S3 PF15753.5 OWF38634.1 - 0.65 10.1 5.3 1.4 9.0 5.3 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF1700 PF08006.11 OWF38634.1 - 0.75 9.3 4.4 0.3 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF1664 PF07889.12 OWF38634.1 - 0.94 9.5 3.9 6.3 6.9 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ly49 PF08391.10 OWF38634.1 - 1.5 9.2 9.5 2.2 8.7 5.9 2.5 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Sigma_reg_N PF13800.6 OWF38634.1 - 1.7 9.0 5.9 4 7.8 2.5 2.4 1 1 1 2 2 2 0 Sigma factor regulator N-terminal Fib_alpha PF08702.10 OWF38634.1 - 2.2 8.5 7.9 5.3 7.2 7.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 OWF38634.1 - 2.3 8.4 8.2 4.4 7.5 8.2 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 LRR_8 PF13855.6 OWF38635.1 - 6.8e-30 102.6 20.0 3.5e-13 49.1 4.8 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OWF38635.1 - 1.5e-19 69.8 33.0 5.1e-07 29.9 2.1 6.1 2 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF38635.1 - 8.5e-09 34.8 29.5 0.44 11.3 0.3 9.9 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 OWF38635.1 - 4e-06 26.5 5.7 0.0062 16.1 0.1 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 OWF38635.1 - 5.4e-06 26.0 31.6 0.39 10.9 0.1 8.7 8 0 0 8 8 8 5 Leucine Rich repeat LRR_5 PF13306.6 OWF38635.1 - 0.0092 15.9 0.2 0.099 12.6 0.1 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) GCD14 PF08704.10 OWF38636.1 - 3.1e-103 344.7 0.0 4.6e-103 344.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 OWF38636.1 - 1.9e-07 31.0 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 OWF38636.1 - 1.5e-06 28.0 0.2 4.2e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.6 OWF38636.1 - 0.006 17.6 0.0 0.022 15.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF38636.1 - 0.025 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Vault_4 PF17796.1 OWF38636.1 - 0.03 14.4 0.1 3 8.0 0.0 2.9 3 0 0 3 3 3 0 Major Vault Protein repeat domain Galactosyl_T PF01762.21 OWF38637.1 - 1.3e-35 123.0 0.1 1.9e-35 122.5 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Pex24p PF06398.11 OWF38637.1 - 0.16 10.9 1.2 0.31 10.0 1.2 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin VWA PF00092.28 OWF38639.1 - 3.9e-160 528.7 29.8 2.1e-44 151.9 4.3 4.0 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_2 PF13519.6 OWF38639.1 - 8.9e-59 196.8 3.4 4.7e-16 59.4 0.1 4.7 5 0 0 5 5 5 4 von Willebrand factor type A domain VWA_3 PF13768.6 OWF38639.1 - 3.6e-20 72.5 0.0 5.7e-05 23.1 0.0 4.7 4 1 0 4 4 4 4 von Willebrand factor type A domain Copine PF07002.16 OWF38639.1 - 9.6e-05 21.9 5.9 0.027 13.9 0.3 3.5 3 0 0 3 3 3 1 Copine AhpC-TSA_2 PF13911.6 OWF38639.1 - 0.0018 18.4 1.0 18 5.5 0.0 4.4 4 0 0 4 4 4 1 AhpC/TSA antioxidant enzyme RTT107_BRCT_5 PF16770.5 OWF38639.1 - 0.0028 17.5 0.5 3.8 7.5 0.0 3.2 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain NOG1 PF06858.14 OWF38639.1 - 0.0066 16.2 3.2 19 5.1 0.0 4.8 5 0 0 5 5 5 1 Nucleolar GTP-binding protein 1 (NOG1) DUF3726 PF12525.8 OWF38639.1 - 0.071 13.2 0.1 94 3.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3726) SIS PF01380.22 OWF38639.1 - 0.61 9.9 3.3 4.2 7.2 0.0 3.7 5 0 0 5 5 5 0 SIS domain VWA PF00092.28 OWF38640.1 - 7.6e-253 830.6 56.4 6.4e-45 153.5 5.4 6.1 6 0 0 6 6 6 6 von Willebrand factor type A domain VWA_2 PF13519.6 OWF38640.1 - 2.1e-96 317.8 16.7 1.4e-15 57.9 0.1 6.6 6 0 0 6 6 6 6 von Willebrand factor type A domain VWA_3 PF13768.6 OWF38640.1 - 7.8e-49 165.6 5.4 4.8e-08 33.1 0.0 6.2 6 0 0 6 6 6 6 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF38640.1 - 2.2e-18 66.5 5.8 0.0033 16.9 0.0 6.3 6 1 0 6 6 6 5 VWA domain containing CoxE-like protein NOG1 PF06858.14 OWF38640.1 - 1.6e-06 27.8 6.7 8.3 6.3 0.0 6.9 7 0 0 7 7 7 1 Nucleolar GTP-binding protein 1 (NOG1) Copine PF07002.16 OWF38640.1 - 0.0013 18.3 19.7 2.8 7.3 0.7 6.4 6 1 0 6 6 6 3 Copine Tex_YqgF PF16921.5 OWF38640.1 - 0.0014 19.0 9.8 3.6 8.1 0.0 5.8 6 0 0 6 6 6 2 Tex protein YqgF-like domain DUF3726 PF12525.8 OWF38640.1 - 0.0019 18.2 0.2 22 5.2 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3726) ACP_PD PF04336.12 OWF38640.1 - 0.0078 16.6 0.2 11 6.5 0.1 3.6 3 0 0 3 3 3 1 Acyl carrier protein phosphodiesterase DUF4625 PF15418.6 OWF38640.1 - 0.049 13.9 0.2 0.61 10.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) FAM35_C PF15793.5 OWF38640.1 - 0.14 11.5 2.8 50 3.2 0.0 4.4 5 0 0 5 5 5 0 Protein family FAM35, C-terminal Eisosome1 PF12757.7 OWF38640.1 - 2.7 8.3 10.7 10 6.4 0.0 4.9 6 0 0 6 6 5 0 Eisosome protein 1 CutC PF03932.14 OWF38640.1 - 5.8 6.3 13.5 12 5.3 0.1 5.1 5 1 1 6 6 6 0 CutC family Sulfotransfer_1 PF00685.27 OWF38641.1 - 7.9e-05 22.3 0.0 0.0001 21.9 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 OWF38642.1 - 8.1e-29 100.9 3.5 9.1e-29 100.8 3.5 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Met_10 PF02475.16 OWF38643.1 - 6.9e-63 212.0 0.0 1.4e-62 211.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 OWF38643.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase YedD PF13987.6 OWF38643.1 - 0.18 11.6 0.4 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 YedD-like protein MAT1 PF06391.13 OWF38644.1 - 4.2e-57 193.3 19.4 5e-57 193.0 19.4 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OWF38644.1 - 1.4e-13 50.5 2.8 3.3e-13 49.3 2.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF38644.1 - 0.00022 21.1 4.8 0.00078 19.4 4.8 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF38644.1 - 0.00075 19.5 4.8 0.0021 18.1 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF38644.1 - 0.0032 17.3 6.6 0.012 15.5 6.6 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OWF38644.1 - 0.0033 17.5 5.3 0.011 15.9 0.2 2.9 1 1 1 2 2 2 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 OWF38644.1 - 0.0081 16.0 5.1 0.025 14.4 5.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF38644.1 - 0.02 15.2 4.5 0.02 15.2 4.5 2.9 2 1 0 2 2 1 0 Ring finger domain AAA_23 PF13476.6 OWF38644.1 - 0.14 12.6 9.2 0.19 12.2 9.2 1.1 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 OWF38644.1 - 0.94 8.3 2.5 1.1 8.0 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF16 PF01519.16 OWF38644.1 - 6.8 7.2 13.5 3.2 8.3 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ion_trans_2 PF07885.16 OWF38645.1 - 3.2e-34 116.7 19.8 2.3e-18 65.9 1.7 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF38645.1 - 5.1e-06 25.9 9.7 0.045 13.0 7.6 2.2 1 1 1 2 2 2 2 Ion transport protein PIRT PF15099.6 OWF38645.1 - 0.37 10.4 1.4 4.1 7.0 0.2 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family p47_phox_C PF08944.11 OWF38645.1 - 1.5 8.3 6.5 2.7 7.5 6.5 1.3 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain LRR_8 PF13855.6 OWF38646.1 - 6.6e-16 57.8 28.3 3.5e-08 33.1 4.6 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OWF38646.1 - 3.8e-12 46.2 23.3 0.0012 19.2 0.6 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF38646.1 - 0.0026 18.0 16.9 7.3 7.6 0.4 6.7 5 1 0 5 5 5 1 Leucine Rich Repeat YHS PF04945.13 OWF38646.1 - 0.049 13.7 0.4 0.11 12.6 0.4 1.6 1 0 0 1 1 1 0 YHS domain LRR_5 PF13306.6 OWF38646.1 - 0.16 11.9 1.0 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Gal-bind_lectin PF00337.22 OWF38647.1 - 6.6e-113 372.0 2.3 8.5e-40 135.4 0.3 3.1 3 0 0 3 3 3 3 Galactoside-binding lectin WIF PF02019.18 OWF38647.1 - 6.6e-06 25.9 0.1 0.18 11.5 0.0 3.3 3 0 0 3 3 3 2 WIF domain Sulfatase PF00884.23 OWF38648.1 - 9.8e-70 235.4 0.0 1.4e-69 234.9 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OWF38648.1 - 2.2e-26 93.0 0.4 3.6e-26 92.3 0.4 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OWF38648.1 - 2.9e-05 23.8 0.5 0.001 18.8 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase TatD_DNase PF01026.21 OWF38649.1 - 0.053 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase Myb_DNA-bind_4 PF13837.6 OWF38650.1 - 2.5e-14 53.4 0.6 5.7e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain zf-C2H2_jaz PF12171.8 OWF38650.1 - 0.0018 18.5 0.9 0.0042 17.3 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Myb_DNA-bind_6 PF13921.6 OWF38650.1 - 0.0026 18.0 0.1 0.0051 17.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 OWF38650.1 - 0.1 13.5 0.3 0.32 11.9 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger MADF_DNA_bdg PF10545.9 OWF38650.1 - 0.14 12.5 0.5 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 7tm_1 PF00001.21 OWF38651.1 - 1.9e-14 53.7 17.6 2.7e-14 53.1 17.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF38651.1 - 6.7e-05 22.3 22.5 0.0013 18.1 22.5 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Mucin PF01456.17 OWF38652.1 - 5.9 6.9 27.6 8.2 6.4 26.4 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein TatD_DNase PF01026.21 OWF38653.1 - 3e-08 33.3 0.0 3.6e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 OWF38653.1 - 0.016 15.0 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase MH2 PF03166.14 OWF38654.1 - 2.8e-45 154.8 0.0 3.9e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 OWF38654.1 - 2.3e-25 88.8 2.2 4e-25 88.0 1.4 1.8 1 1 1 2 2 2 1 MH1 domain Dymeclin PF09742.9 OWF38655.1 - 1.1e-169 565.9 9.4 1.2e-169 565.7 9.4 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 OWF38655.1 - 2.3e-07 29.4 18.7 0.0001 20.6 6.9 3.5 3 1 1 4 4 4 2 High-temperature-induced dauer-formation protein zf-H2C2_2 PF13465.6 OWF38656.1 - 1.9e-61 201.9 124.4 9.2e-07 29.0 0.3 18.7 18 0 0 18 18 18 16 Zinc-finger double domain zf-C2H2 PF00096.26 OWF38656.1 - 1.1e-45 151.6 151.3 0.00034 20.9 0.3 17.4 17 0 0 17 17 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF38656.1 - 1.6e-41 137.4 145.3 0.0014 19.3 0.5 17.3 17 0 0 17 17 17 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF38656.1 - 3.7e-14 52.6 107.0 0.0039 17.4 2.4 17.1 17 0 0 17 17 17 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF38656.1 - 7.7e-09 35.7 81.9 0.0069 16.7 1.0 13.9 15 0 0 15 15 15 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF38656.1 - 8e-07 28.9 130.6 0.0019 18.1 0.7 17.5 18 0 0 18 18 18 11 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF38656.1 - 0.035 14.4 67.1 0.56 10.5 5.1 8.7 4 2 6 10 10 10 0 C2H2-type zinc ribbon AT_hook PF02178.19 OWF38656.1 - 0.93 9.6 86.1 1.3 9.1 3.0 9.0 8 0 0 8 8 8 0 AT hook motif BolA PF01722.18 OWF38656.1 - 4.2 7.7 14.4 1.6 9.1 0.1 6.0 4 3 1 5 5 5 0 BolA-like protein Spike_NTD PF16451.5 OWF38657.1 - 0.0022 17.4 0.9 6.9 5.9 0.1 3.3 1 1 2 3 3 3 3 Spike glycoprotein N-terminal domain DUF5493 PF17597.2 OWF38657.1 - 0.04 14.2 15.8 0.31 11.3 0.2 5.2 1 1 2 3 3 3 0 Family of unknown function (DUF5493) Inositol_P PF00459.25 OWF38657.1 - 0.52 9.8 7.3 29 4.1 0.3 5.1 1 1 3 4 4 4 0 Inositol monophosphatase family DUF5603 PF18231.1 OWF38658.1 - 0.00034 20.9 1.8 17 5.8 0.1 4.5 1 1 3 4 4 4 3 Domain of unknown function (DUF5603) Inositol_P PF00459.25 OWF38658.1 - 0.03 13.8 1.9 12 5.3 0.2 4.2 2 1 1 3 3 3 0 Inositol monophosphatase family DUF3791 PF12668.7 OWF38658.1 - 0.058 13.4 1.8 36 4.5 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3791) DUF5493 PF17597.2 OWF38658.1 - 0.086 13.1 12.2 1.2 9.5 1.1 4.7 1 1 2 3 3 3 0 Family of unknown function (DUF5493) LexA_DNA_bind PF01726.16 OWF38658.1 - 0.32 10.8 6.4 39 4.1 0.1 5.3 3 2 4 7 7 7 0 LexA DNA binding domain DUF1686 PF07937.11 OWF38658.1 - 0.69 9.8 7.3 12 5.7 0.2 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1686) Ferlin_C PF16165.5 OWF38659.1 - 0.069 13.1 0.4 5 7.0 0.0 3.1 2 2 1 3 3 3 0 Ferlin C-terminus PUA_3 PF17785.1 OWF38660.1 - 0.077 12.8 2.1 32 4.4 0.1 4.9 4 1 1 5 5 5 0 PUA-like domain zf-B_box PF00643.24 OWF38661.1 - 1.2e-13 51.0 21.4 4.6e-07 29.9 9.6 2.4 2 0 0 2 2 2 2 B-box zinc finger Fez1 PF06818.15 OWF38661.1 - 0.002 18.6 7.9 0.002 18.6 7.9 1.5 2 0 0 2 2 2 1 Fez1 ECM11 PF15463.6 OWF38661.1 - 0.0026 18.3 0.1 0.055 14.0 0.0 2.5 1 1 0 2 2 2 1 Extracellular mutant protein 11 DREPP PF05558.12 OWF38661.1 - 0.0087 16.0 2.6 0.014 15.3 2.6 1.3 1 0 0 1 1 1 1 DREPP plasma membrane polypeptide ZZ PF00569.17 OWF38661.1 - 0.024 14.5 8.3 0.024 14.5 8.3 2.7 2 0 0 2 2 2 0 Zinc finger, ZZ type Cluap1 PF10234.9 OWF38661.1 - 0.027 13.9 4.1 0.039 13.3 4.1 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 YtxH PF12732.7 OWF38661.1 - 0.035 14.6 1.9 3.2 8.4 1.3 2.6 2 1 0 2 2 2 0 YtxH-like protein CdvA PF18822.1 OWF38661.1 - 0.047 13.5 5.7 1.3 8.9 1.8 2.5 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF5082 PF16888.5 OWF38661.1 - 0.088 13.1 4.3 0.29 11.4 4.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) IBR PF01485.21 OWF38661.1 - 0.32 11.2 16.4 0.51 10.6 4.4 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain OmpH PF03938.14 OWF38661.1 - 0.51 10.7 4.8 0.81 10.0 1.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SAS4 PF15460.6 OWF38661.1 - 0.64 10.1 12.6 2.8 8.1 0.6 3.7 4 1 1 5 5 5 0 Something about silencing, SAS, complex subunit 4 DUF1664 PF07889.12 OWF38661.1 - 0.72 9.9 2.9 1.3 9.0 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2716 PF10898.8 OWF38661.1 - 1.2 9.5 3.9 5.1 7.5 3.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2716) TMPIT PF07851.13 OWF38661.1 - 2.8 7.1 7.7 15 4.7 7.7 2.0 1 1 0 1 1 1 0 TMPIT-like protein Siva PF05458.12 OWF38661.1 - 6.4 6.4 14.7 7.1 6.3 3.2 2.4 1 1 1 2 2 2 0 Cd27 binding protein (Siva) MIF4G PF02854.19 OWF38663.1 - 6.3e-13 48.9 7.9 8e-13 48.5 7.9 1.1 1 0 0 1 1 1 1 MIF4G domain DRIM PF07539.12 OWF38663.1 - 0.0029 16.0 0.0 0.0038 15.6 0.0 1.1 1 0 0 1 1 1 1 Down-regulated in metastasis Sulfotransfer_1 PF00685.27 OWF38664.1 - 1.2e-17 64.3 0.5 1.4e-17 64.1 0.5 1.0 1 0 0 1 1 1 1 Sulfotransferase domain SpoVIF PF14069.6 OWF38664.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F Sulfotransfer_1 PF00685.27 OWF38665.1 - 2.1e-22 79.9 0.0 1.7e-21 76.9 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF38665.1 - 0.038 14.4 0.0 7 7.0 0.0 2.2 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF38666.1 - 3.3e-54 184.2 0.2 3.3e-53 180.9 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF38666.1 - 8.9e-07 29.5 0.0 7.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family TFIIA_gamma_N PF02268.16 OWF38667.1 - 1.8e-23 82.3 0.3 2.6e-23 81.7 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 OWF38667.1 - 5.6e-22 77.6 3.7 1e-21 76.8 3.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit LysM PF01476.20 OWF38668.1 - 5.4e-05 23.2 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain ERAP1_C PF11838.8 OWF38669.1 - 0 1376.8 23.8 6.5e-87 292.0 0.2 5.6 5 0 0 5 5 5 5 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OWF38669.1 - 0 1305.9 37.4 2.4e-81 272.4 2.7 5.7 5 0 0 5 5 5 5 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OWF38669.1 - 1.2e-246 811.3 19.6 5.2e-50 170.2 0.1 5.8 5 0 0 5 5 5 5 Peptidase M1 N-terminal domain Aminopep PF10023.9 OWF38669.1 - 1.3e-13 51.1 4.1 0.29 10.4 0.0 5.5 5 0 0 5 5 5 5 Putative aminopeptidase Peptidase_MA_2 PF13485.6 OWF38669.1 - 5.8e-12 45.8 4.8 0.00013 21.7 0.0 5.5 5 0 0 5 5 5 2 Peptidase MA superfamily BSP PF04450.12 OWF38669.1 - 5.5e-06 26.3 6.6 13 5.5 0.0 6.1 5 0 0 5 5 5 2 Peptidase of plants and bacteria SprT-like PF10263.9 OWF38669.1 - 0.00015 21.6 0.0 44 4.0 0.0 5.6 5 0 0 5 5 5 0 SprT-like family Peptidase_M91 PF14891.6 OWF38669.1 - 0.0027 18.1 0.7 1.3e+02 2.8 0.0 4.8 5 0 0 5 5 5 0 Effector protein WLM PF08325.10 OWF38669.1 - 0.0049 17.0 1.5 1.2e+02 2.6 0.0 5.2 5 0 0 5 5 5 0 WLM domain DUF3612 PF12268.8 OWF38669.1 - 0.012 15.7 0.2 26 4.9 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3612) RHD_DNA_bind PF00554.22 OWF38669.1 - 0.031 14.2 2.3 1.1 9.2 0.0 3.8 4 0 0 4 4 4 0 Rel homology DNA-binding domain CDH PF02611.15 OWF38669.1 - 0.058 13.0 0.6 1.5 8.4 0.0 3.3 4 0 0 4 4 4 0 CDP-diacylglycerol pyrophosphatase zf-B_box PF00643.24 OWF38670.1 - 1.5e-10 41.0 25.5 1.5e-08 34.7 7.1 4.6 5 0 0 5 5 5 2 B-box zinc finger zf-C3HC4_4 PF15227.6 OWF38670.1 - 8e-09 35.5 6.8 8e-09 35.5 6.8 3.7 3 1 1 4 4 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF38670.1 - 1.3e-08 34.5 4.4 1.3e-08 34.5 4.4 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF38670.1 - 6.1e-08 32.4 5.8 6.1e-08 32.4 5.8 4.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF38670.1 - 1.1e-07 31.8 2.2 1.1e-07 31.8 2.2 3.6 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF38670.1 - 7.4e-06 25.7 7.6 7.4e-06 25.7 7.6 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF38670.1 - 2e-05 24.3 3.8 2e-05 24.3 3.8 3.5 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF38670.1 - 6.1e-05 22.9 7.8 6.1e-05 22.9 7.8 3.7 2 1 1 3 3 3 1 zinc-RING finger domain Prominin PF05478.11 OWF38670.1 - 0.00093 17.3 1.9 0.0015 16.6 1.9 1.3 1 0 0 1 1 1 1 Prominin zf-RING_2 PF13639.6 OWF38670.1 - 0.0019 18.5 10.5 0.0019 18.5 10.5 4.0 3 1 0 3 3 3 1 Ring finger domain COG5 PF10392.9 OWF38670.1 - 0.0047 17.1 0.7 0.36 11.0 0.0 2.5 1 1 0 2 2 2 1 Golgi transport complex subunit 5 YlqD PF11068.8 OWF38670.1 - 0.0063 16.9 1.5 0.0063 16.9 1.5 2.1 1 1 1 2 2 2 1 YlqD protein Lant_dehydr_C PF14028.6 OWF38670.1 - 0.019 14.5 1.5 0.12 11.9 1.5 2.0 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Trm112p PF03966.16 OWF38670.1 - 0.055 14.0 0.6 0.76 10.4 0.1 2.9 2 1 0 2 2 2 0 Trm112p-like protein RNase_E_G PF10150.9 OWF38670.1 - 0.098 12.1 2.9 0.16 11.4 2.9 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family DUF948 PF06103.11 OWF38670.1 - 0.19 12.0 2.5 0.92 9.8 0.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 OWF38670.1 - 0.25 11.2 7.5 0.78 9.6 7.5 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 OWF38670.1 - 0.31 10.6 3.4 0.5 9.9 3.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ApoLp-III PF07464.11 OWF38670.1 - 0.52 10.4 3.8 0.66 10.1 2.7 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.6 OWF38670.1 - 0.56 9.5 3.2 0.81 9.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4349 PF14257.6 OWF38670.1 - 0.81 9.1 6.8 2.7 7.4 4.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF745 PF05335.13 OWF38670.1 - 1 9.0 6.7 0.54 10.0 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TMPIT PF07851.13 OWF38670.1 - 1.8 7.7 6.3 0.63 9.2 2.9 1.9 1 1 1 2 2 2 0 TMPIT-like protein TraC PF07820.12 OWF38671.1 - 0.0058 16.9 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 TraC-like protein PK PF00224.21 OWF38672.1 - 1.1e-160 534.2 1.8 1.7e-160 533.6 1.8 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OWF38672.1 - 9e-35 119.4 0.2 2.6e-34 117.9 0.1 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OWF38672.1 - 0.019 14.1 2.0 0.027 13.6 0.0 2.3 3 0 0 3 3 3 0 HpcH/HpaI aldolase/citrate lyase family Amnionless PF14828.6 OWF38673.1 - 1.9e-98 330.2 0.0 2.2e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 Amnionless PetG PF02529.15 OWF38673.1 - 0.37 10.7 1.4 0.69 9.8 1.4 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 zf-RING_6 PF14835.6 OWF38674.1 - 0.0003 20.6 2.8 0.00069 19.4 2.8 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 OWF38674.1 - 0.00031 20.5 1.7 0.00066 19.5 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF38674.1 - 0.0019 18.1 4.6 0.0041 17.0 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF38674.1 - 0.0043 17.1 5.1 0.0094 16.0 5.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF38674.1 - 0.0046 17.1 4.8 0.012 15.8 4.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF38674.1 - 0.02 14.8 4.6 0.036 13.9 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MATH PF00917.26 OWF38674.1 - 0.026 14.7 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 MATH domain Prok-RING_4 PF14447.6 OWF38674.1 - 0.052 13.4 5.5 0.11 12.4 5.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OWF38674.1 - 0.46 10.4 3.0 1 9.3 3.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF38674.1 - 1.1 9.6 6.6 1.3 9.4 4.1 2.3 1 1 1 2 2 2 0 Ring finger domain Zn_ribbon_17 PF17120.5 OWF38674.1 - 2 8.1 9.2 3.8 7.2 7.7 2.2 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OWF38675.1 - 0.006 16.4 9.4 0.006 16.4 9.4 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FlgN PF05130.12 OWF38675.1 - 0.0082 16.7 1.1 0.015 15.8 1.1 1.4 1 0 0 1 1 1 1 FlgN protein ADK_lid PF05191.14 OWF38675.1 - 0.015 15.3 6.6 1.8 8.6 0.4 3.6 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-TRAF PF02176.18 OWF38676.1 - 1.2e-15 57.9 33.6 1.5e-12 48.0 4.8 4.2 2 2 1 3 3 3 3 TRAF-type zinc finger Sina PF03145.16 OWF38676.1 - 0.00058 19.9 22.2 0.051 13.5 1.7 3.4 1 1 2 3 3 3 2 Seven in absentia protein family T2SSM PF04612.12 OWF38676.1 - 0.0063 16.6 3.3 0.53 10.3 0.0 2.2 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M DASH_Spc19 PF08287.11 OWF38676.1 - 0.0066 16.4 8.2 0.013 15.5 8.2 1.4 1 0 0 1 1 1 1 Spc19 GvpL_GvpF PF06386.11 OWF38676.1 - 0.0077 16.2 2.5 0.012 15.6 2.5 1.2 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF zf-C3HC4_3 PF13920.6 OWF38676.1 - 0.018 14.9 7.9 0.018 14.9 7.9 3.5 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) DUF3584 PF12128.8 OWF38676.1 - 0.021 12.4 8.9 0.029 11.9 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TSC22 PF01166.18 OWF38676.1 - 0.04 14.2 2.0 0.14 12.5 2.0 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family His_Phos_2 PF00328.22 OWF38676.1 - 0.31 10.3 2.8 0.59 9.4 1.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) FlaC_arch PF05377.11 OWF38676.1 - 0.39 11.2 9.4 4.3 7.8 4.6 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HemX PF04375.14 OWF38676.1 - 0.4 9.9 7.9 0.61 9.3 7.9 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Snapin_Pallidin PF14712.6 OWF38676.1 - 0.48 10.9 7.6 1.4e+02 3.0 7.4 2.7 2 1 0 2 2 1 0 Snapin/Pallidin SpoIISA_toxin PF14171.6 OWF38676.1 - 0.52 10.0 3.1 0.89 9.2 3.1 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF724 PF05266.14 OWF38676.1 - 0.73 9.6 10.0 1.7 8.5 10.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 OWF38676.1 - 0.89 9.7 8.9 5.6 7.2 7.2 2.7 1 1 1 2 2 2 0 bZIP transcription factor Cnn_1N PF07989.11 OWF38676.1 - 0.93 9.7 8.6 2.2 8.5 5.1 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 AAA_17 PF13207.6 OWF38676.1 - 1.5 9.2 6.7 3.9 7.9 4.0 2.3 2 0 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.22 OWF38676.1 - 2.1 8.6 10.4 6.2 7.1 10.3 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 OWF38676.1 - 2.4 7.4 5.3 3.8 6.8 5.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 OWF38676.1 - 3.1 8.5 11.6 9.2 6.9 9.4 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 OWF38676.1 - 5.5 6.3 7.5 8.2 5.7 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 OWF38676.1 - 6.3 5.9 9.2 4.1 6.6 6.6 1.4 1 1 1 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 OWF38676.1 - 8.7 6.9 15.1 93 3.6 14.9 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 zf-TRAF PF02176.18 OWF38678.1 - 1.5e-18 67.2 21.8 5.7e-14 52.5 6.4 2.4 1 1 1 2 2 2 2 TRAF-type zinc finger zf-ACC PF17848.1 OWF38678.1 - 0.021 14.9 0.2 0.021 14.9 0.2 2.1 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain MIF4G_like_2 PF09090.11 OWF38678.1 - 0.024 14.1 1.6 0.035 13.6 1.6 1.2 1 0 0 1 1 1 0 MIF4G like Sina PF03145.16 OWF38678.1 - 0.026 14.5 3.2 0.026 14.5 3.2 3.4 1 1 2 3 3 3 0 Seven in absentia protein family zf_C2H2_13 PF18508.1 OWF38678.1 - 0.055 13.1 6.9 1.5 8.5 0.4 2.9 1 1 1 2 2 2 0 Zinc finger domain zf_UBZ PF18439.1 OWF38678.1 - 0.091 12.4 0.2 0.091 12.4 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TMF_DNA_bd PF12329.8 OWF38678.1 - 0.092 12.8 11.4 0.034 14.1 5.8 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF745 PF05335.13 OWF38678.1 - 0.62 9.8 3.1 0.53 10.0 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) zf-TRAF_2 PF15965.5 OWF38678.1 - 0.75 10.3 18.1 0.055 13.9 10.0 2.1 1 1 2 3 3 3 0 TRAF-like zinc-finger JIP_LZII PF16471.5 OWF38678.1 - 2.7 8.3 12.9 5.7 7.2 4.8 3.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Csm1_N PF18504.1 OWF38678.1 - 3 8.2 19.5 0.27 11.6 3.0 3.8 2 1 2 4 4 4 0 Csm1 N-terminal domain Synaptobrevin PF00957.21 OWF38678.1 - 3.1 7.7 5.0 18 5.2 0.4 2.5 1 1 1 2 2 2 0 Synaptobrevin DUF4477 PF14780.6 OWF38679.1 - 7.6e-35 120.3 4.4 7.6e-35 120.3 4.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4477) zf-RING_2 PF13639.6 OWF38680.1 - 0.00029 21.1 6.8 0.00029 21.1 6.8 2.4 1 1 1 2 2 2 1 Ring finger domain zf-4CXXC_R1 PF10497.9 OWF38680.1 - 0.007 16.6 1.5 0.007 16.6 1.5 2.3 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_5 PF14634.6 OWF38680.1 - 0.017 15.1 5.9 0.017 15.1 5.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 OWF38680.1 - 0.026 14.7 1.9 0.026 14.7 1.9 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain PHD PF00628.29 OWF38680.1 - 0.029 14.3 5.0 0.029 14.3 5.0 2.4 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 OWF38680.1 - 0.35 11.2 16.2 0.045 14.1 5.2 2.8 2 1 0 2 2 2 0 RING-like domain zf-rbx1 PF12678.7 OWF38680.1 - 1.7 9.0 17.5 0.18 12.1 6.3 2.7 1 1 1 2 2 2 0 RING-H2 zinc finger domain Lyase_1 PF00206.20 OWF38681.1 - 3.4e-112 374.9 0.0 5.1e-112 374.3 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OWF38681.1 - 6.4e-25 87.3 0.0 1.9e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus HTH_Tnp_Tc5 PF03221.16 OWF38681.1 - 3.8e-13 49.2 0.2 2e-12 46.9 0.1 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 OWF38681.1 - 2.6e-10 39.8 1.4 7e-10 38.4 1.4 1.8 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 OWF38681.1 - 3.7e-05 23.7 0.0 0.0017 18.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.6 OWF38681.1 - 0.0015 18.3 0.4 0.019 14.8 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_37 PF13744.6 OWF38681.1 - 0.019 14.9 1.8 0.26 11.3 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 OWF38681.1 - 0.037 14.2 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.16 OWF38681.1 - 0.13 12.0 0.0 0.41 10.4 0.0 1.9 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_38 PF13936.6 OWF38681.1 - 0.87 9.4 3.1 12 5.8 0.1 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain Pkinase_Tyr PF07714.17 OWF38682.1 - 7e-93 310.6 0.0 1.1e-92 310.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF38682.1 - 2.8e-43 148.2 0.0 1.1e-42 146.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OWF38682.1 - 0.0013 17.7 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain MrpF_PhaF PF04066.13 OWF38682.1 - 0.0079 16.6 1.5 0.017 15.5 1.5 1.5 1 0 0 1 1 1 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) APH PF01636.23 OWF38682.1 - 0.17 11.7 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF38682.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 OWF38686.1 - 6.7e-25 85.0 2.1 0.0051 16.8 0.1 9.0 9 0 0 9 9 9 4 Leucine Rich repeat EF-hand_1 PF00036.32 OWF38686.1 - 1.9e-08 33.3 6.8 0.00041 19.7 1.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF38686.1 - 2.9e-08 33.0 4.2 0.00016 21.3 0.6 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF38686.1 - 3.1e-07 30.7 1.5 3.1e-07 30.7 1.5 2.3 2 0 0 2 2 2 1 EF-hand domain pair LRR_1 PF00560.33 OWF38686.1 - 9.4e-07 28.5 0.1 40 5.3 0.0 6.6 6 0 0 6 6 6 0 Leucine Rich Repeat EF-hand_5 PF13202.6 OWF38686.1 - 4.3e-06 26.0 9.5 0.0034 16.8 2.1 2.8 2 0 0 2 2 2 2 EF hand LRR_4 PF12799.7 OWF38686.1 - 6.4e-06 26.4 3.6 0.24 11.9 0.4 5.3 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 OWF38686.1 - 0.00016 21.4 4.4 0.12 12.3 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair LRR_8 PF13855.6 OWF38686.1 - 0.0044 16.8 6.7 1.1 9.0 1.4 4.9 4 1 1 5 5 5 2 Leucine rich repeat EF-hand_11 PF08976.11 OWF38686.1 - 0.012 16.5 0.2 0.029 15.2 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain LRR_6 PF13516.6 OWF38687.1 - 7.7e-25 84.8 16.1 0.00092 19.1 0.0 9.1 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 OWF38687.1 - 2.4e-06 27.8 10.2 0.15 12.5 1.7 5.7 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF38687.1 - 0.00032 20.8 7.1 2.4 9.1 0.1 6.2 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 OWF38687.1 - 0.0011 18.6 7.7 0.0088 15.8 1.2 4.8 5 1 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.6 OWF38688.1 - 5.1e-25 85.4 0.9 0.0028 17.6 0.0 8.2 9 0 0 9 9 9 5 Leucine Rich repeat EF-hand_7 PF13499.6 OWF38688.1 - 2.1e-09 37.7 0.6 2.1e-09 37.7 0.6 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF38688.1 - 4.1e-09 35.3 2.0 2.5e-05 23.5 0.8 2.9 2 0 0 2 2 2 2 EF hand LRR_1 PF00560.33 OWF38688.1 - 1e-08 34.5 0.0 3.6 8.5 0.0 6.8 7 0 0 7 7 7 1 Leucine Rich Repeat EF-hand_6 PF13405.6 OWF38688.1 - 3.1e-08 32.9 0.9 0.0034 17.2 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF38688.1 - 3.9e-07 29.3 3.4 0.0065 15.9 0.7 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF38688.1 - 2.7e-05 23.9 1.0 0.00013 21.8 0.2 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_14 PF17959.1 OWF38688.1 - 0.0063 16.8 1.1 0.02 15.2 0.3 2.4 2 0 0 2 2 2 1 EF-hand domain LRR_4 PF12799.7 OWF38688.1 - 0.07 13.6 7.7 7.6 7.1 0.1 5.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) She9_MDM33 PF05546.11 OWF38688.1 - 0.15 11.9 1.1 0.31 10.8 1.1 1.5 1 1 0 1 1 1 0 She9 / Mdm33 family LRR_8 PF13855.6 OWF38688.1 - 1.6 8.6 7.7 2 8.2 0.5 4.7 4 1 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 OWF38689.1 - 3.2e-29 98.5 22.8 0.0028 17.6 0.1 10.5 10 0 0 10 10 10 8 Leucine Rich repeat LRR_1 PF00560.33 OWF38689.1 - 1.7e-07 30.8 0.1 7.9 7.5 0.1 7.8 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 OWF38689.1 - 1.3e-06 28.6 5.8 0.022 15.2 0.1 5.2 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF38689.1 - 0.015 15.0 0.7 0.015 15.0 0.7 4.6 3 2 1 4 4 4 0 Leucine rich repeat Rad51 PF08423.11 OWF38690.1 - 3.5e-26 92.0 0.0 4.8e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OWF38690.1 - 2.1e-09 37.2 0.0 2.7e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OWF38690.1 - 5.2e-08 32.5 0.1 1.1e-07 31.5 0.1 1.7 2 1 0 2 2 2 1 KaiC RecA PF00154.21 OWF38690.1 - 0.0004 19.9 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein RNA_pol_A_CTD PF03118.15 OWF38690.1 - 0.0018 18.0 0.4 0.0034 17.1 0.4 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA_24 PF13479.6 OWF38690.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 OWF38690.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein ABC_tran PF00005.27 OWF38690.1 - 0.12 12.8 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Rad51 PF08423.11 OWF38691.1 - 0.00014 21.2 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 DUF4538 PF15061.6 OWF38692.1 - 5.7 6.7 50.7 28 4.6 0.1 13.4 6 4 8 16 16 16 0 Domain of unknown function (DUF4538) Sugar_tr PF00083.24 OWF38693.1 - 1.4e-29 103.3 6.3 5.3e-17 61.8 2.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF38693.1 - 1.5e-26 93.2 34.0 1e-23 83.8 18.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2105 PF09878.9 OWF38693.1 - 1.5 8.5 9.2 0.52 10.0 5.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2105) Zona_pellucida PF00100.23 OWF38694.1 - 9.9e-10 38.6 2.5 1.3e-09 38.2 2.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Abhydrolase_1 PF00561.20 OWF38696.1 - 1.2e-11 44.7 0.0 1.1e-07 31.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF38696.1 - 4e-11 42.6 0.0 2.3e-10 40.2 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 OWF38696.1 - 0.0019 18.2 0.1 0.0034 17.4 0.1 1.4 1 0 0 1 1 1 1 Cutinase Casein PF00363.18 OWF38699.1 - 6.4 7.2 23.8 2.3e+02 2.2 5.8 4.5 1 1 2 3 3 3 0 Casein TC1 PF15063.6 OWF38699.1 - 8.4 6.3 5.2 38 4.2 0.4 3.3 1 1 2 3 3 3 0 Thyroid cancer protein 1 fn3 PF00041.21 OWF38700.1 - 7.4e-60 199.3 15.7 3e-14 53.1 0.1 5.5 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 OWF38700.1 - 1.5e-56 188.4 0.2 3.1e-14 52.8 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF38700.1 - 1.1e-51 173.3 6.8 2.4e-13 50.5 0.1 5.8 5 0 0 5 5 4 4 Immunoglobulin domain Ig_2 PF13895.6 OWF38700.1 - 2.2e-33 114.4 1.7 6.7e-08 32.8 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 OWF38700.1 - 2e-30 104.8 1.8 3.6e-09 36.7 0.0 5.2 5 0 0 5 5 4 4 Immunoglobulin domain C2-set_2 PF08205.12 OWF38700.1 - 3.5e-16 59.0 1.1 0.0053 16.8 0.0 5.3 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 OWF38700.1 - 2.5e-14 53.6 13.1 0.00068 20.2 0.0 6.0 6 0 0 6 6 5 3 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 OWF38700.1 - 9.8e-14 51.5 9.8 0.15 12.2 0.0 8.5 4 4 3 7 7 7 3 Immunoglobulin V-set domain Interfer-bind PF09294.10 OWF38700.1 - 3.4e-09 37.0 4.4 0.026 14.8 0.0 4.8 5 0 0 5 5 5 3 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 OWF38700.1 - 2.2e-07 30.3 0.1 0.004 16.7 0.0 3.9 4 0 0 4 4 3 1 Immunoglobulin domain Ig_4 PF16680.5 OWF38700.1 - 6.9e-07 29.4 0.0 0.43 10.9 0.0 4.9 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain fn3_2 PF16893.5 OWF38700.1 - 0.00018 21.6 1.2 0.0022 18.1 0.0 2.8 3 0 0 3 3 3 1 Fibronectin type III domain Tissue_fac PF01108.17 OWF38700.1 - 0.00089 19.1 3.4 3.1 7.7 0.0 4.4 4 0 0 4 4 4 1 Tissue factor DUF2369 PF10179.9 OWF38700.1 - 0.0037 17.6 0.5 12 6.4 0.0 4.5 5 0 0 5 5 4 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 OWF38700.1 - 0.0079 16.1 1.7 5.2 7.1 0.0 3.6 4 0 0 4 4 4 1 Fibronectin-III type domain Y_Y_Y PF07495.13 OWF38700.1 - 0.074 13.0 0.0 0.93 9.5 0.0 2.7 2 0 0 2 2 2 0 Y_Y_Y domain Adeno_E3_CR1 PF02440.15 OWF38700.1 - 0.095 12.5 1.2 1.2 8.9 0.0 3.2 3 1 0 3 3 3 0 Adenovirus E3 region protein CR1 Glyco_hydro_36C PF16874.5 OWF38700.1 - 0.096 13.2 0.0 2 9.0 0.0 2.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 36 C-terminal domain DUF1410 PF07198.11 OWF38700.1 - 0.53 10.8 0.0 0.53 10.8 0.0 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF1410) Adeno_E3_CR2 PF02439.15 OWF38700.1 - 2.9 7.7 8.2 7.7 6.4 8.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Arylsulfotran_N PF17425.2 OWF38700.1 - 4.6 7.4 9.5 64 3.7 0.1 4.6 5 0 0 5 5 5 0 Arylsulfotransferase Ig-like domain Reprolysin_2 PF13574.6 OWF38701.1 - 3.1e-32 112.1 1.4 6.6e-32 111.0 1.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF38701.1 - 6.1e-26 91.8 0.8 2.1e-25 90.1 0.8 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF38701.1 - 2.6e-18 66.7 0.2 7.2e-18 65.3 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF38701.1 - 6.9e-11 42.2 2.2 2.7e-10 40.2 0.9 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 OWF38701.1 - 1.1e-10 41.8 0.1 2.5e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.23 OWF38701.1 - 1.4e-08 35.4 29.2 1.4e-08 35.4 29.2 4.1 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.19 OWF38701.1 - 0.0006 19.8 0.0 0.0045 16.9 0.0 2.5 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.9 OWF38701.1 - 0.003 16.6 0.2 0.0056 15.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 DUF2207 PF09972.9 OWF38702.1 - 0.063 12.0 0.6 0.44 9.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OWF38702.1 - 0.1 12.9 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) IBV_3A PF03617.13 OWF38702.1 - 0.12 12.4 0.6 0.27 11.2 0.6 1.5 1 0 0 1 1 1 0 IBV 3A protein TcdB_N PF12918.7 OWF38702.1 - 0.38 11.1 6.0 0.67 10.3 1.2 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain LINES_C PF14695.6 OWF38704.1 - 0.11 12.0 0.1 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Lines C-terminus DUF2207 PF09972.9 OWF38705.1 - 0.056 12.2 0.1 0.21 10.3 0.0 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OWF38705.1 - 0.086 13.1 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) IBV_3A PF03617.13 OWF38705.1 - 0.094 12.7 0.3 0.22 11.6 0.3 1.6 1 0 0 1 1 1 0 IBV 3A protein zf-RING_UBOX PF13445.6 OWF38707.1 - 9.4e-10 38.4 7.5 9.4e-10 38.4 7.5 2.8 3 1 1 4 4 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF38707.1 - 1.3e-07 31.8 9.6 1.3e-07 31.8 9.6 3.3 2 1 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 OWF38707.1 - 1.8e-07 30.9 10.1 1.8e-07 30.9 10.1 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF38707.1 - 4.7e-07 29.5 5.5 4.7e-07 29.5 5.5 4.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF38707.1 - 1.6e-06 28.2 11.9 1.6e-06 28.2 11.9 2.8 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF38707.1 - 1.9e-06 27.6 8.6 1.9e-06 27.6 8.6 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF38707.1 - 3.3e-06 27.1 5.1 3.3e-06 27.1 5.1 4.3 4 2 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 OWF38707.1 - 4.3e-06 26.6 8.9 4.3e-06 26.6 8.9 3.2 3 1 0 3 3 2 1 zinc-RING finger domain Baculo_PEP_C PF04513.12 OWF38707.1 - 0.012 15.6 4.6 0.018 15.1 4.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LepA_C PF06421.12 OWF38707.1 - 0.038 14.1 1.1 0.038 14.1 1.1 1.9 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Hex_IIIa PF02455.16 OWF38707.1 - 0.11 11.2 1.0 0.15 10.8 1.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF948 PF06103.11 OWF38707.1 - 0.14 12.5 2.3 0.25 11.6 2.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spermine_synt_N PF17284.2 OWF38708.1 - 8e-66 217.8 60.1 19 5.2 0.0 56.3 8 3 99 107 107 107 5 Spermidine synthase tetramerisation domain DNA_pol_B_N PF18094.1 OWF38708.1 - 1.8e-06 28.4 125.0 94 3.6 0.1 48.0 2 2 88 91 91 91 0 DNA polymerase beta N-terminal domain PBP5_C PF07943.13 OWF38709.1 - 8.6e-13 48.3 9.6 2.9 8.2 0.0 10.4 4 2 3 9 9 9 4 Penicillin-binding protein 5, C-terminal domain Spermine_synt_N PF17284.2 OWF38709.1 - 7.7e-10 38.5 3.9 15 5.6 0.0 12.3 13 3 3 16 16 16 1 Spermidine synthase tetramerisation domain DNA_pol_B_N PF18094.1 OWF38709.1 - 1.9e-07 31.5 36.8 50 4.5 0.1 17.9 2 1 19 23 23 23 0 DNA polymerase beta N-terminal domain PilJ_C PF18223.1 OWF38709.1 - 1.1e-06 29.1 0.7 5.6 7.5 0.0 6.6 2 2 7 10 10 10 1 Pili PilJ C-terminal domain DUF2415 PF10313.9 OWF38709.1 - 0.00015 21.6 22.3 85 3.2 0.1 14.0 8 4 10 18 18 18 0 Uncharacterised protein domain (DUF2415) Gelsolin PF00626.22 OWF38709.1 - 0.0016 18.3 12.5 53 3.8 0.2 10.8 2 2 6 9 9 9 0 Gelsolin repeat HNH_repeat PF18780.1 OWF38709.1 - 0.062 13.1 0.0 24 4.8 0.0 5.0 4 0 0 4 4 4 0 Homing endonuclease repeat PPIP5K2_N PF18086.1 OWF38709.1 - 0.38 10.9 3.5 83 3.4 0.0 4.3 4 0 0 4 4 4 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Membrane_bind PF14564.6 OWF38709.1 - 5.2 7.5 8.0 1.2e+02 3.1 0.1 5.9 2 1 6 9 9 9 0 Membrane binding Anophelin PF10731.9 OWF38709.1 - 9.3 6.2 10.3 40 4.1 0.1 6.6 5 3 2 7 7 7 0 Thrombin inhibitor from mosquito Spermine_synt_N PF17284.2 OWF38710.1 - 4.4e-08 32.9 0.1 2.6 8.0 0.0 6.1 2 1 7 9 9 9 3 Spermidine synthase tetramerisation domain PBP5_C PF07943.13 OWF38710.1 - 1e-05 25.7 1.3 0.75 10.1 0.1 3.7 1 1 2 3 3 3 2 Penicillin-binding protein 5, C-terminal domain DNA_pol_B_N PF18094.1 OWF38710.1 - 7.3e-05 23.3 7.3 14 6.3 0.0 5.8 1 1 5 6 6 6 1 DNA polymerase beta N-terminal domain DUF2415 PF10313.9 OWF38710.1 - 0.00012 22.0 4.7 21 5.1 0.2 7.3 2 2 4 6 6 6 0 Uncharacterised protein domain (DUF2415) CBS PF00571.28 OWF38710.1 - 0.017 15.6 13.7 32 5.1 0.5 5.8 2 1 1 3 3 3 0 CBS domain Phage_fiber_C PF06820.12 OWF38710.1 - 0.036 14.4 2.2 4.7 7.6 0.1 3.2 1 1 3 4 4 4 0 Putative prophage tail fibre C-terminus Gelsolin PF00626.22 OWF38710.1 - 0.17 11.8 0.1 41 4.2 0.1 3.5 2 2 1 3 3 3 0 Gelsolin repeat GNVR PF13807.6 OWF38710.1 - 0.28 11.2 10.2 9.4 6.2 0.1 4.7 1 1 4 5 5 5 0 G-rich domain on putative tyrosine kinase 30K_MP_C_Ter PF11330.8 OWF38710.1 - 1.4 8.2 6.9 9.1 5.5 0.2 3.9 1 1 3 4 4 4 0 C-Terminal of 30K viral movement proteins Spermine_synt_N PF17284.2 OWF38711.1 - 1.2e-10 41.0 1.5 10 6.1 0.0 9.2 7 5 4 11 11 11 5 Spermidine synthase tetramerisation domain DUF2415 PF10313.9 OWF38711.1 - 2.6e-05 24.0 4.7 6.3 6.8 0.1 7.9 6 2 3 9 9 9 1 Uncharacterised protein domain (DUF2415) Gelsolin PF00626.22 OWF38711.1 - 0.0057 16.5 2.3 66 3.5 0.0 6.0 2 1 3 5 5 5 0 Gelsolin repeat SWC7 PF17330.2 OWF38711.1 - 0.038 14.1 8.0 24 5.1 0.1 6.1 2 2 4 9 9 9 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 DUF2415 PF10313.9 OWF38712.1 - 2.1e-05 24.3 1.4 0.36 10.8 0.1 4.2 1 1 3 4 4 4 3 Uncharacterised protein domain (DUF2415) Spermine_synt_N PF17284.2 OWF38713.1 - 4.4e-07 29.7 0.4 8.5 6.4 0.0 6.2 3 3 7 10 10 10 2 Spermidine synthase tetramerisation domain DUF2415 PF10313.9 OWF38713.1 - 1e-05 25.4 11.1 23 5.0 0.1 8.8 4 3 6 10 10 10 2 Uncharacterised protein domain (DUF2415) PBP5_C PF07943.13 OWF38713.1 - 0.0012 19.0 2.1 3.2 8.1 0.1 3.8 1 1 2 3 3 3 2 Penicillin-binding protein 5, C-terminal domain DUF4980 PF16352.5 OWF38713.1 - 0.0054 16.7 1.9 2.6 8.1 0.0 3.9 1 1 3 4 4 4 1 Domain of unknown function (DUF4980) Phage_fiber_C PF06820.12 OWF38713.1 - 0.0084 16.4 6.4 0.71 10.3 0.1 3.8 1 1 4 5 5 5 1 Putative prophage tail fibre C-terminus DNA_pol_B_N PF18094.1 OWF38713.1 - 0.019 15.5 8.8 28 5.3 0.1 5.7 2 2 5 7 7 7 0 DNA polymerase beta N-terminal domain Mucin-like PF16058.5 OWF38714.1 - 0.033 14.3 0.2 5.2 7.2 0.1 3.2 1 1 2 3 3 3 0 Mucin-like Sushi PF00084.20 OWF38715.1 - 0.0032 18.0 0.1 0.0056 17.3 0.1 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) MARVEL PF01284.23 OWF38715.1 - 0.05 13.6 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2970 PF11174.8 OWF38715.1 - 0.14 12.0 0.6 0.21 11.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Caveolin PF01146.17 OWF38716.1 - 4.3e-24 85.0 0.4 5.2e-24 84.7 0.4 1.1 1 0 0 1 1 1 1 Caveolin Ras PF00071.22 OWF38717.1 - 7.9e-64 214.1 0.3 9.4e-64 213.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF38717.1 - 1.2e-35 122.3 0.1 2e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF38717.1 - 7e-13 48.4 0.2 9.4e-13 48.0 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF38717.1 - 1.7e-07 31.3 0.1 2.7e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF38717.1 - 3.5e-05 23.8 0.3 0.017 15.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OWF38717.1 - 4.2e-05 23.2 0.2 0.00025 20.6 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OWF38717.1 - 4.3e-05 23.8 0.2 0.00049 20.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 OWF38717.1 - 0.002 17.5 0.1 0.0035 16.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OWF38717.1 - 0.0099 16.3 0.1 0.016 15.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OWF38717.1 - 0.01 15.3 0.1 0.021 14.2 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 OWF38717.1 - 0.014 15.9 0.4 0.023 15.2 0.4 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 OWF38717.1 - 0.019 15.0 0.2 0.065 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OWF38717.1 - 0.02 14.4 0.2 0.061 12.9 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OWF38717.1 - 0.021 14.6 0.0 0.054 13.2 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OWF38717.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OWF38717.1 - 0.06 12.8 0.0 0.25 10.7 0.0 1.9 1 1 0 2 2 2 0 Bacterial TniB protein FAD-SLDH PF12318.8 OWF38717.1 - 0.1 12.7 0.3 0.23 11.5 0.1 1.7 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_21 PF13304.6 OWF38717.1 - 0.14 11.9 1.0 0.3 10.8 0.5 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Ras PF00071.22 OWF38718.1 - 7.4e-61 204.5 0.3 9e-61 204.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF38718.1 - 3.8e-34 117.5 0.1 6.4e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF38718.1 - 9.6e-14 51.2 0.2 1.3e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF38718.1 - 1.6e-07 31.4 0.1 2.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF38718.1 - 2.3e-07 30.4 0.1 3.4e-07 29.9 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OWF38718.1 - 5e-06 26.5 0.3 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OWF38718.1 - 2.5e-05 23.9 0.5 0.00023 20.8 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OWF38718.1 - 0.00046 20.5 0.3 0.005 17.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 OWF38718.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OWF38718.1 - 0.0033 17.0 0.8 0.013 15.0 0.8 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OWF38718.1 - 0.0037 17.7 0.0 0.0058 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OWF38718.1 - 0.0065 17.0 0.4 0.011 16.3 0.4 1.6 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 OWF38718.1 - 0.0092 16.4 0.2 0.032 14.6 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 OWF38718.1 - 0.024 14.4 0.0 0.069 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OWF38718.1 - 0.052 14.1 0.2 0.18 12.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OWF38718.1 - 0.062 13.2 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 OWF38718.1 - 0.098 12.7 0.1 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-C3HC4 PF00097.25 OWF38719.1 - 9.2e-08 31.8 9.8 9.2e-08 31.8 9.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF38719.1 - 5.8e-07 29.2 12.5 5.8e-07 29.2 12.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF38719.1 - 7.3e-06 25.7 13.4 7.3e-06 25.7 13.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF38719.1 - 1.1e-05 25.3 13.0 2.2e-05 24.4 11.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF38719.1 - 1.1e-05 25.6 12.8 1.1e-05 25.6 12.8 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OWF38719.1 - 0.00034 20.5 8.4 0.00034 20.5 8.4 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF38719.1 - 0.0044 17.1 13.1 0.0044 17.1 13.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OWF38719.1 - 0.89 9.7 5.4 2.7 8.1 5.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ank_2 PF12796.7 OWF38720.1 - 6.8e-31 106.7 0.0 1e-15 58.1 0.0 2.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38720.1 - 7.6e-23 80.6 0.0 5e-09 36.5 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF38720.1 - 1.7e-19 69.3 0.1 4.2e-07 30.1 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OWF38720.1 - 8.7e-18 62.6 0.0 2.9e-05 24.1 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OWF38720.1 - 7e-17 61.3 0.0 1.7e-06 28.2 0.0 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) CesT PF05932.13 OWF38720.1 - 0.12 12.5 1.0 2.8 8.1 0.1 2.8 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family Selenoprotein_S PF06936.11 OWF38720.1 - 0.21 11.4 7.5 0.45 10.3 7.5 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Cluap1 PF10234.9 OWF38720.1 - 0.28 10.5 11.2 0.61 9.4 11.2 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 GrpE PF01025.19 OWF38720.1 - 0.3 10.7 10.2 0.88 9.2 9.8 1.9 2 0 0 2 2 2 0 GrpE Ribosomal_L12 PF00542.19 OWF38720.1 - 0.64 10.4 6.7 1.1 9.7 4.0 2.9 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain YnfE PF17452.2 OWF38720.1 - 0.83 10.0 5.9 2.3 8.6 5.9 1.7 1 0 0 1 1 1 0 Uncharacterized YnfE-like Dzip-like_N PF13815.6 OWF38720.1 - 1.9 8.5 9.1 4.4 7.3 9.1 1.6 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Sigma70_ner PF04546.13 OWF38720.1 - 7.2 6.4 15.8 0.89 9.4 11.5 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region ALMT PF11744.8 OWF38721.1 - 0.18 10.6 3.5 0.29 9.9 3.5 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-C2H2 PF00096.26 OWF38722.1 - 2.1e-40 135.0 134.9 7.9e-05 22.9 2.8 17.7 17 0 0 17 17 17 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF38722.1 - 2.7e-35 118.0 127.5 0.00097 19.8 1.5 17.6 17 0 0 17 17 17 16 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF38722.1 - 3.4e-23 81.0 123.3 3.6e-05 24.0 2.8 17.3 18 0 0 18 18 18 11 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF38722.1 - 4.5e-06 26.5 0.1 4.5e-06 26.5 0.1 16.8 17 0 0 17 17 17 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF38722.1 - 0.00011 22.4 97.8 0.012 15.9 0.2 15.0 15 0 0 15 15 15 7 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OWF38722.1 - 0.0008 19.6 74.3 0.022 15.1 3.1 11.0 9 2 1 10 10 10 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 OWF38722.1 - 0.0057 17.3 7.3 0.0057 17.3 7.3 10.6 6 3 3 9 9 9 3 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 OWF38722.1 - 0.31 11.5 91.1 0.21 12.1 1.2 14.6 15 0 0 15 15 15 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 OWF38722.1 - 0.63 10.2 69.8 0.2 11.8 0.5 11.6 9 3 2 11 11 11 0 Zinc ribbon domain GAGA PF09237.11 OWF38722.1 - 2 8.3 20.1 8.2 6.3 0.0 7.1 8 0 0 8 8 8 0 GAGA factor HMG_box PF00505.19 OWF38724.1 - 1e-19 70.7 0.4 2.6e-19 69.4 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF38724.1 - 4.2e-12 46.5 0.5 1.3e-11 44.9 0.2 2.0 1 1 0 1 1 1 1 HMG-box domain DUF812 PF05667.11 OWF38724.1 - 0.00092 18.2 6.0 0.0012 17.8 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMCO5 PF14992.6 OWF38724.1 - 0.0037 16.9 3.7 0.0037 16.9 3.7 2.0 2 0 0 2 2 2 1 TMCO5 family CHDNT PF08073.12 OWF38724.1 - 0.0068 16.3 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 CHDNT (NUC034) domain DUF3450 PF11932.8 OWF38724.1 - 0.012 14.9 0.7 0.012 14.9 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 OWF38724.1 - 0.023 14.1 0.2 0.039 13.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RasGAP_C PF03836.15 OWF38724.1 - 0.046 13.9 1.1 0.046 13.9 1.1 2.2 2 0 0 2 2 2 0 RasGAP C-terminus DUF4763 PF15960.5 OWF38724.1 - 0.66 9.2 9.7 1.1 8.6 9.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) CEP209_CC5 PF16574.5 OWF38724.1 - 1.1 9.4 14.2 0.04 14.1 4.7 2.2 1 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 ATG16 PF08614.11 OWF38724.1 - 1.2 9.3 12.7 0.86 9.8 10.3 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1043 PF06295.12 OWF38724.1 - 1.8 8.6 7.1 0.23 11.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) YabA PF06156.13 OWF38724.1 - 2.2 9.0 7.2 0.43 11.3 2.5 2.1 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 OWF38724.1 - 8.2 6.6 12.3 0.22 11.6 3.3 2.8 3 1 0 3 3 3 0 bZIP transcription factor PC_rep PF01851.22 OWF38725.1 - 0.00011 22.5 2.0 93 3.7 0.0 6.1 3 2 5 8 8 8 0 Proteasome/cyclosome repeat MCR PF18509.1 OWF38725.1 - 1.2 8.8 41.1 22 4.7 0.1 10.0 11 0 0 11 11 11 0 Magnetochrome domain NUC202 PF08166.12 OWF38725.1 - 8.7 6.5 10.3 45 4.2 0.5 4.2 1 1 1 2 2 2 0 NUC202 domain G-alpha PF00503.20 OWF38726.1 - 9.2e-114 380.3 3.5 1e-113 380.1 3.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OWF38726.1 - 1.1e-13 51.1 2.2 2.4e-10 40.1 0.2 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF38726.1 - 0.0016 17.9 2.7 0.049 13.0 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OWF38726.1 - 0.0064 16.7 2.7 4.2 7.6 0.1 3.3 1 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Chitin_synth_2 PF03142.15 OWF38727.1 - 1.1e-27 96.9 2.5 1.1e-27 96.9 2.5 3.5 3 1 1 4 4 4 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF38727.1 - 9.8e-17 61.5 1.3 5.2e-16 59.2 1.3 2.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 SAM_1 PF00536.30 OWF38727.1 - 7.7e-15 55.1 0.6 3.4e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF38727.1 - 1.4e-14 53.9 0.2 1.5e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Glyco_tranf_2_3 PF13641.6 OWF38727.1 - 1.7e-08 34.7 0.0 3.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OWF38727.1 - 5.9e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OWF38727.1 - 0.00012 22.0 0.0 0.00044 20.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 LAP1C PF05609.12 OWF38727.1 - 0.0012 18.1 9.9 0.12 11.4 0.0 2.4 2 0 0 2 2 2 2 Lamina-associated polypeptide 1C (LAP1C) Phage_holin_3_5 PF16085.5 OWF38727.1 - 7.6 6.7 8.1 4.5 7.4 0.7 2.8 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III VWA PF00092.28 OWF38728.1 - 6.9e-32 111.1 0.9 1e-31 110.5 0.9 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF38728.1 - 2.9e-11 44.0 0.0 6.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF38728.1 - 0.00015 21.9 27.3 0.0013 18.8 0.7 4.5 3 2 2 5 5 5 2 Chitin binding Peritrophin-A domain VWA_3 PF13768.6 OWF38728.1 - 0.0007 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain SWI-SNF_Ssr4 PF08549.10 OWF38728.1 - 2.6 6.6 4.4 3.6 6.1 4.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-C2H2 PF00096.26 OWF38729.1 - 3e-44 147.1 109.6 7.6e-06 26.1 0.4 14.1 14 0 0 14 14 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF38729.1 - 1.6e-38 128.0 103.4 0.00056 20.5 0.2 14.7 14 0 0 14 14 14 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF38729.1 - 3.7e-23 80.9 104.5 1.7e-05 25.0 1.5 15.2 15 1 0 15 15 15 10 Zinc-finger double domain zf-met PF12874.7 OWF38729.1 - 4.5e-20 71.3 89.5 0.011 16.1 1.4 13.2 14 0 0 14 14 14 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF38729.1 - 1.5e-19 69.7 79.6 3.3e-05 24.0 2.8 12.7 12 0 0 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF38729.1 - 8.6e-09 35.2 92.6 0.0024 17.8 0.2 12.4 12 1 1 13 13 13 8 C2H2-type zinc finger ASL_C PF08328.11 OWF38729.1 - 4.7e-07 29.9 8.3 51 4.0 0.0 8.4 1 1 7 8 8 8 0 Adenylosuccinate lyase C-terminal GAGA PF09237.11 OWF38729.1 - 0.016 15.0 10.6 0.43 10.4 0.0 4.4 4 0 0 4 4 4 0 GAGA factor DUF4337 PF14235.6 OWF38729.1 - 0.49 10.5 4.1 1.3 9.1 4.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) zf-C2H2_2 PF12756.7 OWF38729.1 - 0.93 9.9 92.7 1.5 9.2 0.5 11.9 1 1 7 9 9 9 0 C2H2 type zinc-finger (2 copies) LRR_6 PF13516.6 OWF38731.1 - 2.4e-16 58.3 12.6 0.00024 20.9 0.1 5.4 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 OWF38731.1 - 0.0018 18.5 2.1 70 4.6 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 OWF38731.1 - 0.027 14.9 9.2 2.7 8.6 0.1 5.2 3 2 4 7 7 7 0 Leucine Rich repeats (2 copies) Sushi PF00084.20 OWF38734.1 - 1.8e-06 28.4 0.1 3.7e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Shisa PF13908.6 OWF38734.1 - 0.015 15.6 0.3 0.025 14.8 0.2 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF38734.1 - 0.029 15.3 0.1 0.049 14.5 0.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 OWF38734.1 - 0.048 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis LapA_dom PF06305.11 OWF38734.1 - 0.16 11.8 0.6 0.25 11.2 0.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Mid2 PF04478.12 OWF38734.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM132D_C PF15706.5 OWF38734.1 - 0.2 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Ion_trans PF00520.31 OWF38737.1 - 1.2e-34 119.7 15.6 1.5e-34 119.3 15.6 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF38737.1 - 3.2e-24 85.1 0.0 6.5e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF38737.1 - 1.3e-11 44.3 9.1 3.9e-11 42.8 9.1 1.8 1 0 0 1 1 1 1 Ion channel BTB_3 PF16017.5 OWF38737.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Claudin_2 PF13903.6 OWF38737.1 - 4 7.2 7.5 0.28 10.9 0.2 2.5 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Aminopep PF10023.9 OWF38738.1 - 0.003 17.0 1.0 3.3 7.0 0.1 3.3 1 1 3 4 4 4 3 Putative aminopeptidase DUF1178 PF06676.11 OWF38739.1 - 0.65 10.4 3.8 13 6.1 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1178) HATPase_c_3 PF13589.6 OWF38740.1 - 2.9e-12 46.6 1.0 4.3e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OWF38740.1 - 6.8e-07 29.8 0.2 1.3e-06 28.9 0.1 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PapD-like PF14874.6 OWF38741.1 - 2.4e-08 34.1 0.0 6.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASH PF15780.5 OWF38741.1 - 1.5e-06 28.3 0.0 0.0029 17.8 0.1 2.8 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 OWF38741.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Transmembrane protein 131-like EF1_GNE PF00736.19 OWF38742.1 - 2.4e-30 104.6 4.1 4.3e-30 103.7 4.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OWF38742.1 - 1.3e-10 41.5 9.1 1.3e-10 41.5 9.1 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_6 PF17171.4 OWF38742.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain YL1 PF05764.13 OWF38742.1 - 0.33 11.0 5.2 0.41 10.7 5.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Molybdopterin PF00384.22 OWF38743.1 - 2.7e-73 247.4 0.0 1.6e-72 244.8 0.0 2.1 2 1 0 2 2 2 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 OWF38743.1 - 6.7e-21 74.1 0.2 1.5e-20 73.0 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 OWF38743.1 - 3.4e-17 62.9 0.1 7.6e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 OWF38743.1 - 2e-16 59.2 0.2 5.5e-16 57.8 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 OWF38743.1 - 7.9e-10 38.6 1.8 1.1e-09 38.2 0.3 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 OWF38743.1 - 0.0049 16.6 0.1 4.1 7.1 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Pkinase PF00069.25 OWF38744.1 - 2e-41 142.1 0.0 5.3e-41 140.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38744.1 - 4.4e-40 137.6 0.0 8e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.23 OWF38744.1 - 5.5e-18 65.6 0.0 5.5e-18 65.6 0.0 3.5 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OWF38744.1 - 3.6e-08 33.5 0.1 8.6e-07 29.0 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 OWF38744.1 - 2.9e-05 23.5 0.3 0.0061 15.9 0.0 3.1 3 0 0 3 3 3 1 AIG1 family T2SSE PF00437.20 OWF38744.1 - 0.036 13.1 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OWF38744.1 - 0.093 12.6 2.4 0.32 10.9 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 OWF38744.1 - 0.15 12.6 1.1 0.75 10.3 0.0 2.7 3 0 0 3 3 3 0 ABC transporter LXG PF04740.12 OWF38744.1 - 0.19 11.4 17.4 0.018 14.7 2.4 3.9 4 0 0 4 4 4 0 LXG domain of WXG superfamily Dynamin_N PF00350.23 OWF38745.1 - 8.7e-18 64.9 10.0 1.3e-17 64.4 0.0 3.9 3 2 1 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 OWF38745.1 - 5.8e-09 36.0 1.9 2.1e-07 31.0 0.0 3.8 3 2 0 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 OWF38745.1 - 6e-06 25.7 1.0 0.0021 17.4 0.0 3.5 4 0 0 4 4 4 1 AIG1 family cobW PF02492.19 OWF38745.1 - 0.0079 15.8 0.0 0.041 13.5 0.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OWF38745.1 - 0.0087 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OWF38745.1 - 0.024 14.5 3.0 0.16 11.8 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase DUF659 PF04937.15 OWF38745.1 - 0.024 14.5 0.1 0.084 12.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) MHC_I_3 PF16497.5 OWF38745.1 - 0.036 13.6 0.0 0.09 12.2 0.0 1.7 1 0 0 1 1 1 0 MHC-I family domain ArdA PF07275.11 OWF38745.1 - 0.042 14.5 3.7 2.8 8.5 3.2 2.8 2 0 0 2 2 2 0 Antirestriction protein (ArdA) ABC_tran PF00005.27 OWF38745.1 - 0.082 13.4 1.0 0.44 11.1 0.0 2.6 3 0 0 3 3 3 0 ABC transporter SRPRB PF09439.10 OWF38745.1 - 0.084 12.3 0.7 0.59 9.5 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Roc PF08477.13 OWF38745.1 - 0.099 12.9 0.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OWF38745.1 - 0.13 12.6 1.4 0.71 10.2 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain DUF4337 PF14235.6 OWF38745.1 - 2.3 8.3 5.4 4.9 7.2 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1514 PF07438.11 OWF38745.1 - 2.3 8.1 4.4 25 4.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) Pkinase PF00069.25 OWF38746.1 - 7.9e-43 146.7 0.0 2.1e-42 145.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38746.1 - 1.1e-42 146.2 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OWF38746.1 - 0.03 13.3 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 OWF38746.1 - 0.065 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PIP5K PF01504.18 OWF38747.1 - 1.3e-75 254.2 0.2 1.7e-75 253.8 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Neur_chan_LBD PF02931.23 OWF38748.1 - 4.2e-51 173.5 3.8 6.8e-51 172.8 3.8 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF38748.1 - 8.8e-43 147.1 0.0 3.3e-42 145.2 0.0 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4680 PF15730.5 OWF38748.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) FAM220 PF15487.6 OWF38748.1 - 0.16 11.6 0.1 0.33 10.5 0.1 1.4 1 1 0 1 1 1 0 FAM220 family Thiamine_BP PF01910.17 OWF38748.1 - 0.17 11.8 0.2 0.36 10.8 0.2 1.5 1 0 0 1 1 1 0 Thiamine-binding protein A_amylase_inhib PF01356.19 OWF38749.1 - 0.0028 17.6 3.8 3.9 7.5 0.0 4.2 4 0 0 4 4 4 2 Alpha amylase inhibitor MBD PF01429.19 OWF38749.1 - 0.021 14.5 3.0 20 5.0 0.6 3.8 3 1 0 3 3 3 0 Methyl-CpG binding domain LCAT PF02450.15 OWF38750.1 - 0.0049 16.1 0.1 1.3 8.2 0.0 2.0 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase GAPES3 PF17154.4 OWF38751.1 - 0.15 12.1 4.1 2.5 8.1 0.2 2.8 1 1 3 4 4 4 0 Gammaproteobacterial periplasmic sensor domain Acetyltransf_13 PF13880.6 OWF38751.1 - 0.39 10.7 4.8 21 5.2 0.1 4.7 3 2 3 6 6 6 0 ESCO1/2 acetyl-transferase DUF3692 PF12469.8 OWF38752.1 - 2.6e-05 24.4 0.9 7.1 6.9 0.1 4.6 1 1 2 3 3 3 3 CRISPR-associated protein DUF5591 PF17884.1 OWF38752.1 - 8.2e-05 22.5 12.7 12 5.8 0.1 6.3 1 1 9 10 10 10 7 Domain of unknown function (DUF5591) Sec16_C PF12931.7 OWF38753.1 - 0.13 11.9 0.6 0.19 11.4 0.6 1.2 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Iron_permease PF04120.12 OWF38753.1 - 1.9 8.2 4.6 3.7 7.3 4.6 1.5 1 0 0 1 1 1 0 Low affinity iron permease Xan_ur_permease PF00860.20 OWF38754.1 - 4.9e-21 74.9 0.0 5.5e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 OWF38755.1 - 1.8e-65 221.2 19.6 2.3e-65 220.8 19.6 1.1 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 OWF38756.1 - 2.6e-17 62.6 9.9 3.1e-17 62.4 9.9 1.1 1 0 0 1 1 1 1 Permease family DHR-2 PF06920.13 OWF38757.1 - 8.9e-199 661.5 7.3 1.6e-198 660.7 7.3 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OWF38757.1 - 4.6e-48 163.6 0.0 1.1e-47 162.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 OWF38757.1 - 7.4e-34 116.5 0.8 2.7e-33 114.8 0.8 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 OWF38757.1 - 4e-14 53.0 0.7 2e-13 50.8 0.3 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 OWF38757.1 - 9.7e-05 22.7 0.2 0.00045 20.6 0.2 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain DOCK_N PF16172.5 OWF38757.1 - 0.031 13.2 0.0 0.091 11.7 0.0 1.8 1 0 0 1 1 1 0 DOCK N-terminus PH_8 PF15409.6 OWF38757.1 - 0.091 13.1 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_10 PF15411.6 OWF38757.1 - 0.1 12.9 0.3 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DAGK_acc PF00609.19 OWF38758.1 - 6.1e-52 176.2 0.0 1.4e-51 175.0 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OWF38758.1 - 3.5e-27 94.5 0.1 9.8e-27 93.1 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 OWF38758.1 - 3.6e-17 62.0 28.2 1.2e-08 34.7 8.6 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.17 OWF38758.1 - 5.3e-17 61.7 0.2 1.4e-16 60.4 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF38758.1 - 4.7e-16 59.0 0.3 9.6e-16 58.0 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 OWF38758.1 - 1.5e-14 54.4 0.6 1.5e-14 54.4 0.6 2.1 3 0 0 3 3 3 1 PH domain PH_3 PF14593.6 OWF38758.1 - 7.6e-05 22.8 0.8 0.00022 21.3 0.6 1.9 2 0 0 2 2 2 1 PH domain C1_2 PF03107.16 OWF38758.1 - 0.0015 18.8 16.4 0.017 15.4 5.9 2.8 2 0 0 2 2 2 2 C1 domain PH_11 PF15413.6 OWF38758.1 - 0.0017 18.7 7.3 0.0036 17.7 3.4 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain Dak2 PF02734.17 OWF38758.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 DAK2 domain DEAD PF00270.29 OWF38759.1 - 1.8e-43 148.3 0.4 3e-43 147.6 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF38759.1 - 3e-33 114.5 0.4 3.9e-31 107.7 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF38759.1 - 6.5e-08 32.8 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OWF38759.1 - 0.00044 20.6 0.2 0.004 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF38759.1 - 0.00079 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF38759.1 - 0.0048 17.2 0.3 0.018 15.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 OWF38759.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 OWF38759.1 - 0.056 13.4 0.0 0.25 11.3 0.0 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain Qn_am_d_aIV PF09100.10 OWF38759.1 - 0.088 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV NACHT PF05729.12 OWF38759.1 - 0.12 12.2 0.0 1.2 9.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Na_K-ATPase PF00287.18 OWF38760.1 - 4.6e-77 259.0 0.1 5.3e-77 258.8 0.1 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain KcnmB2_inactiv PF09303.10 OWF38760.1 - 0.12 12.2 0.1 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 KCNMB2, ball and chain domain zf-RING_2 PF13639.6 OWF38761.1 - 1.2e-12 48.0 7.9 1.2e-12 48.0 7.9 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF38761.1 - 8.5e-11 41.4 3.9 2.2e-10 40.1 3.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OWF38761.1 - 5.2e-08 32.6 7.8 5.2e-08 32.6 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF38761.1 - 5.9e-08 32.4 8.4 1.3e-07 31.3 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF38761.1 - 9.4e-06 25.8 11.5 2.5e-05 24.5 9.9 2.5 3 1 0 3 3 2 1 RING-H2 zinc finger domain PA PF02225.22 OWF38761.1 - 2.3e-05 24.4 0.0 8.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 PA domain zf-RING_5 PF14634.6 OWF38761.1 - 2.3e-05 24.2 5.9 2.3e-05 24.2 5.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF38761.1 - 3.8e-05 23.4 5.9 3.8e-05 23.4 5.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF38761.1 - 0.00032 20.5 6.5 0.00074 19.3 6.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OWF38761.1 - 0.00053 19.9 4.9 0.0044 17.0 5.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger RTA1 PF04479.13 OWF38761.1 - 0.052 13.1 0.5 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 RTA1 like protein zf-ANAPC11 PF12861.7 OWF38761.1 - 0.064 13.3 9.2 0.29 11.2 7.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OWF38761.1 - 0.46 10.1 4.6 1.2 8.8 4.6 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DNA_pol_phi PF04931.13 OWF38761.1 - 0.99 7.4 12.4 1.4 6.9 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_4 PF14570.6 OWF38761.1 - 1.6 8.6 10.5 0.73 9.7 7.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 OWF38761.1 - 2.6 8.2 6.9 6.9 6.9 6.9 1.8 1 0 0 1 1 1 0 RING-variant domain DUF4197 PF13852.6 OWF38762.1 - 5.3e-12 45.9 63.7 35 4.0 0.1 20.7 2 2 28 37 37 37 36 Protein of unknown function (DUF4197) zf-RING_5 PF14634.6 OWF38763.1 - 3.7e-07 30.0 10.7 3.7e-07 30.0 10.7 2.8 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF38763.1 - 0.00012 21.8 11.8 0.00012 21.8 11.8 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF38763.1 - 0.00025 21.1 4.0 0.00025 21.1 4.0 4.2 5 0 0 5 5 5 2 B-box zinc finger DUF3583 PF12126.8 OWF38763.1 - 0.00032 20.3 2.7 0.00049 19.7 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-RING_2 PF13639.6 OWF38763.1 - 0.00034 20.9 11.4 0.00034 20.9 11.4 3.2 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF38763.1 - 0.0046 16.9 7.8 0.0046 16.9 7.8 2.7 2 0 0 2 2 2 1 RING-type zinc-finger Ecm29 PF13001.7 OWF38763.1 - 0.023 13.4 0.4 0.035 12.8 0.4 1.2 1 0 0 1 1 1 0 Proteasome stabiliser Baculo_PEP_C PF04513.12 OWF38763.1 - 0.15 12.1 2.4 0.27 11.3 2.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 OWF38763.1 - 1.9 8.0 4.0 2.2 7.8 1.8 2.0 1 1 1 2 2 2 0 fzo-like conserved region WD40 PF00400.32 OWF38764.1 - 2e-25 88.6 16.5 1.7e-07 31.8 0.4 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF38764.1 - 2.8e-20 72.4 5.0 8.3e-07 29.2 0.4 4.6 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF38764.1 - 3.3e-06 27.1 0.2 0.17 11.8 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF38764.1 - 3.8e-06 26.1 0.5 0.0014 17.7 0.3 2.8 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OWF38764.1 - 0.015 15.3 0.0 0.69 9.9 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 OWF38764.1 - 0.029 13.4 0.3 0.13 11.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) WI12 PF07107.11 OWF38764.1 - 0.11 12.6 0.3 0.29 11.3 0.3 1.6 1 0 0 1 1 1 0 Wound-induced protein WI12 DUF4652 PF15525.6 OWF38764.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) PDR_CDR PF06422.12 OWF38764.1 - 0.15 11.9 0.2 0.37 10.7 0.1 1.7 2 0 0 2 2 2 0 CDR ABC transporter Nup160 PF11715.8 OWF38764.1 - 0.92 8.1 5.6 0.18 10.4 0.3 2.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF1794 PF08768.11 OWF38765.1 - 9.7e-30 103.5 0.0 1.1e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) MTCP1 PF08991.10 OWF38766.1 - 4.9e-17 61.9 11.8 5.5e-17 61.7 11.8 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 OWF38766.1 - 0.00039 20.5 7.7 0.00063 19.8 7.7 1.4 1 1 0 1 1 1 1 CHCH domain DUF1160 PF06648.11 OWF38766.1 - 0.17 11.9 0.0 0.19 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Cmc1 PF08583.10 OWF38766.1 - 1.3 9.1 12.9 0.26 11.4 5.6 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Thymidylate_kin PF02223.17 OWF38767.1 - 1.1e-42 145.8 0.0 1.4e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase PPK2 PF03976.14 OWF38767.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) MobB PF03205.14 OWF38767.1 - 0.069 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 OWF38767.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 OWF38767.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OWF38767.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SAD_SRA PF02182.17 OWF38768.1 - 4.2e-50 169.5 0.0 8.1e-50 168.6 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain Peptidase_S28 PF05577.12 OWF38769.1 - 1.3e-143 478.9 1.0 1.5e-143 478.7 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 OWF38769.1 - 9.6e-05 22.1 0.1 0.00064 19.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF38769.1 - 0.0084 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OWF38769.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SH3_1 PF00018.28 OWF38770.1 - 2.5e-44 148.7 5.1 3.1e-15 55.5 0.1 3.9 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OWF38770.1 - 1.1e-41 140.5 2.3 1.1e-14 54.0 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 OWF38770.1 - 2.3e-34 116.9 0.3 3.2e-11 42.7 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 OWF38770.1 - 1.7e-21 76.1 0.1 4.5e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 OWF38770.1 - 2.6e-10 40.4 6.8 0.0007 19.8 0.2 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_10 PF17902.1 OWF38770.1 - 1.4e-09 37.8 1.1 0.0043 17.1 0.1 3.6 3 0 0 3 3 3 3 SH3 domain SH2_2 PF14633.6 OWF38770.1 - 0.00082 18.8 0.1 0.0024 17.3 0.1 1.6 1 1 0 1 1 1 1 SH2 domain SH3_16 PF18348.1 OWF38770.1 - 0.0092 15.8 0.0 1.6 8.6 0.0 3.0 3 0 0 3 3 3 1 Bacterial dipeptidyl-peptidase Sh3 domain NAD_binding_9 PF13454.6 OWF38770.1 - 0.072 13.1 0.0 15 5.5 0.0 2.4 1 1 1 2 2 2 0 FAD-NAD(P)-binding LPMO_10 PF03067.15 OWF38771.1 - 6.8e-32 111.7 0.4 9.4e-32 111.2 0.4 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading MCPVI PF02993.14 OWF38771.1 - 0.12 12.1 3.6 0.17 11.7 3.6 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Myosin_head PF00063.21 OWF38772.1 - 2.1e-192 641.0 6.2 3.8e-192 640.1 6.2 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 OWF38772.1 - 1.4e-29 102.5 2.1 4.1e-15 56.1 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF38772.1 - 5.6e-23 80.7 5.5 1.8e-06 28.1 0.3 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF38772.1 - 1.5e-22 79.7 3.4 9.3e-08 32.5 0.2 5.9 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF38772.1 - 1e-21 74.6 4.9 2e-05 24.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OWF38772.1 - 7.1e-21 73.7 7.6 7.9e-06 26.1 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat AAA_22 PF13401.6 OWF38772.1 - 0.0024 18.2 0.5 0.0064 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain IQ PF00612.27 OWF38772.1 - 0.01 15.6 0.2 0.027 14.3 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif ABC_tran PF00005.27 OWF38772.1 - 0.059 13.9 0.2 0.66 10.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 OWF38772.1 - 0.18 12.1 0.4 0.74 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ntox35 PF15534.6 OWF38773.1 - 1.9e-13 50.6 8.3 1.7e+02 2.8 0.0 16.7 2 2 29 32 32 32 0 Bacterial toxin 35 DDE_3 PF13358.6 OWF38773.1 - 0.038 13.8 1.8 6.4 6.5 0.0 4.7 1 1 0 3 3 3 0 DDE superfamily endonuclease Urocanase_C PF17392.2 OWF38773.1 - 0.057 12.9 19.6 4.8 6.6 0.1 8.2 1 1 8 10 10 10 0 Urocanase C-terminal domain PRE_C2HC PF07530.11 OWF38773.1 - 0.53 10.4 2.4 86 3.4 0.0 5.3 1 1 1 2 2 2 0 Associated with zinc fingers Caudal_act PF04731.12 OWF38773.1 - 4.5 7.6 25.7 50 4.2 0.1 9.7 2 1 1 3 3 3 0 Caudal like protein activation region DUF4637 PF15470.6 OWF38773.1 - 8.3 6.1 15.6 60 3.3 0.1 6.7 1 1 7 9 9 9 0 Domain of unknown function (DUF4637) COesterase PF00135.28 OWF38774.1 - 1.8e-132 442.8 0.0 2.4e-132 442.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF38774.1 - 1.1e-05 25.4 0.2 3.8e-05 23.6 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF38774.1 - 0.0068 17.0 0.1 0.014 16.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF3432 PF11914.8 OWF38775.1 - 0.065 13.5 0.0 6.8 7.0 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Fibrinogen_BP PF08017.11 OWF38775.1 - 0.77 8.1 17.4 0.87 7.9 17.4 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein DUF2345 PF10106.9 OWF38776.1 - 0.00038 20.4 5.3 1.1 9.2 0.7 3.0 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2345) HU-CCDC81_bac_2 PF18175.1 OWF38776.1 - 0.0028 17.5 1.4 16 5.4 0.0 3.4 1 1 2 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Grp7_allergen PF16984.5 OWF38776.1 - 0.0065 16.5 9.6 0.83 9.7 1.3 3.7 1 1 2 3 3 3 2 Group 7 allergen DUF1997 PF09366.10 OWF38776.1 - 0.01 16.0 0.1 5.1 7.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1997) Attacin_C PF03769.15 OWF38776.1 - 0.021 15.1 1.1 7.3 6.9 0.1 3.1 1 1 1 2 2 2 0 Attacin, C-terminal region Porin_10 PF14121.6 OWF38776.1 - 0.022 13.4 0.7 2 6.9 0.1 2.0 1 1 1 2 2 2 0 Putative porin OMP_b-brl_3 PF14905.6 OWF38776.1 - 0.07 12.1 7.0 0.091 11.7 7.0 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family Adhesin_Dr PF04619.12 OWF38776.1 - 0.23 11.4 18.5 13 5.7 0.5 4.6 1 1 3 4 4 4 0 Dr-family adhesin Arteri_nucleo PF01481.16 OWF38776.1 - 0.32 11.3 6.2 58 4.0 0.0 4.3 1 1 4 5 5 5 0 Arterivirus nucleocapsid protein Big_3_5 PF16640.5 OWF38776.1 - 0.63 10.3 27.9 1.8e+04 -7.6 28.0 3.1 1 1 0 1 1 0 0 Bacterial Ig-like domain (group 3) Epiglycanin_TR PF05647.11 OWF38776.1 - 2.4 8.2 31.8 3.1 7.8 9.7 3.1 1 1 2 3 3 3 0 Tandem-repeating region of mucin, epiglycanin-like Gp5_C PF06715.12 OWF38776.1 - 5.8 7.3 52.4 1.4 9.2 0.3 8.2 5 1 3 8 8 8 0 Gp5 C-terminal repeat (3 copies) COesterase PF00135.28 OWF38777.1 - 1e-14 54.3 0.0 1.2e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF4029 PF13221.6 OWF38778.1 - 0.6 10.8 6.4 8.2 7.2 0.7 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF4029) COesterase PF00135.28 OWF38779.1 - 1.1e-13 50.9 0.0 1.2e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF5359 PF17313.2 OWF38780.1 - 0.043 13.8 3.0 14 5.7 0.1 3.9 1 1 3 4 4 4 0 Family of unknown function (DUF5359) Phage-tail_2 PF09096.10 OWF38780.1 - 0.089 12.7 0.0 9.3 6.2 0.0 2.4 1 1 2 3 3 3 0 Baseplate structural protein, domain 2 DUF4655 PF15548.6 OWF38780.1 - 0.24 10.3 0.1 0.3 10.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) SKICH PF17751.1 OWF38782.1 - 9.9e-21 74.2 0.8 1.8e-20 73.4 0.8 1.5 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 OWF38782.1 - 4.8e-07 29.5 0.1 8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HECW_N PF16562.5 OWF38782.1 - 0.015 15.1 0.3 0.035 13.9 0.1 1.7 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Ribosomal_L6e PF01159.19 OWF38783.1 - 2.9e-37 127.6 0.2 4.4e-37 127.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Cas_GSU0053 PF09617.10 OWF38783.1 - 0.013 15.4 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Metallophos PF00149.28 OWF38784.1 - 6.6e-41 141.0 0.1 8.8e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OWF38784.1 - 1.3e-23 83.2 1.6 2.6e-23 82.2 1.0 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Ank_2 PF12796.7 OWF38785.1 - 3.5e-38 130.1 0.7 6.1e-11 42.8 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38785.1 - 2.5e-28 98.1 13.5 2.2e-08 34.5 0.1 6.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF38785.1 - 1.4e-24 83.5 2.6 0.0031 17.9 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OWF38785.1 - 1.3e-22 79.6 1.8 9.1e-06 25.9 0.1 5.8 3 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF38785.1 - 1.8e-21 75.6 5.5 3e-05 24.3 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat P2X_receptor PF00864.19 OWF38786.1 - 1.3e-140 468.7 1.9 1.5e-140 468.5 1.9 1.0 1 0 0 1 1 1 1 ATP P2X receptor zf-C3HC4_3 PF13920.6 OWF38788.1 - 2.5e-07 30.5 8.5 4.5e-07 29.6 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF38788.1 - 9.2e-06 25.5 10.9 2.7e-05 24.0 11.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF38788.1 - 1.3e-05 24.9 10.9 2.8e-05 23.9 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF38788.1 - 8.1e-05 22.4 5.5 0.00015 21.5 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF38788.1 - 8.9e-05 22.7 5.4 0.00026 21.2 5.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OWF38788.1 - 0.0001 22.1 10.5 0.00021 21.1 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF38788.1 - 0.00056 19.9 7.2 0.0014 18.6 7.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF38788.1 - 0.0013 18.7 1.0 0.0026 17.8 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OWF38788.1 - 0.0015 18.8 9.0 0.0032 17.8 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain HAMP PF00672.25 OWF38788.1 - 0.052 13.9 0.8 3.9 7.9 0.1 3.5 3 0 0 3 3 3 0 HAMP domain PKcGMP_CC PF16808.5 OWF38788.1 - 0.077 12.9 0.3 0.077 12.9 0.3 9.3 10 0 0 10 10 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C3HC4_4 PF15227.6 OWF38788.1 - 0.2 11.9 7.2 0.52 10.5 7.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc_ribbon_15 PF17032.5 OWF38788.1 - 0.21 12.4 4.8 0.77 10.5 4.8 2.0 1 0 0 1 1 1 0 zinc-ribbon family TFA2_Winged_2 PF18121.1 OWF38788.1 - 0.24 11.1 3.1 2.5 7.9 0.2 3.9 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Zn_ribbon_17 PF17120.5 OWF38788.1 - 0.32 10.7 3.9 0.55 9.9 3.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OWF38788.1 - 3.6 7.5 11.6 48 3.9 11.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain VPS9 PF02204.18 OWF38789.1 - 2.4e-20 72.7 0.3 6e-20 71.4 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain UxaE PF16257.5 OWF38789.1 - 0.043 12.5 2.5 0.022 13.5 0.5 1.4 2 0 0 2 2 2 0 tagaturonate epimerase Trypsin_2 PF13365.6 OWF38790.1 - 3.6e-08 34.5 0.0 7.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain CadC_C1 PF18500.1 OWF38790.1 - 0.027 14.6 0.2 0.051 13.7 0.2 1.4 1 0 0 1 1 1 0 CadC C-terminal domain 1 Trypsin_2 PF13365.6 OWF38791.1 - 5.6e-06 27.3 0.6 2.8e-05 25.1 0.0 2.5 2 1 0 2 2 2 1 Trypsin-like peptidase domain MOLO1 PF17175.4 OWF38792.1 - 2.6e-14 53.4 0.1 6.1e-09 36.0 0.1 2.3 1 1 1 2 2 2 2 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 OWF38792.1 - 6.3e-05 23.1 0.2 0.00037 20.7 0.0 2.0 2 0 0 2 2 2 1 TPM domain Abhydrolase_1 PF00561.20 OWF38793.1 - 2.2e-11 43.9 0.1 3.6e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF38793.1 - 1.3e-08 34.4 0.1 6.7e-08 32.1 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PID_2 PF14719.6 OWF38796.1 - 0.047 13.5 0.0 0.76 9.6 0.0 2.2 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Nab6_mRNP_bdg PF10567.9 OWF38797.1 - 0.14 11.6 2.4 0.14 11.6 0.3 2.0 1 1 1 2 2 2 0 RNA-recognition motif Profilin PF00235.19 OWF38798.1 - 2.4e-31 108.6 0.3 2.7e-31 108.5 0.3 1.0 1 0 0 1 1 1 1 Profilin Profilin PF00235.19 OWF38799.1 - 5.9e-35 120.3 0.2 6.5e-35 120.2 0.2 1.0 1 0 0 1 1 1 1 Profilin DEK_C PF08766.11 OWF38802.1 - 0.00081 19.3 1.7 0.011 15.7 0.5 2.8 2 0 0 2 2 2 1 DEK C terminal domain Mab-21 PF03281.14 OWF38803.1 - 5.9e-27 94.7 0.1 1e-26 93.9 0.1 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF38803.1 - 0.0018 18.5 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat NTP_transf_2 PF01909.23 OWF38803.1 - 0.0026 18.0 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain TPR_2 PF07719.17 OWF38803.1 - 0.01 15.9 0.0 1.3 9.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF38803.1 - 0.048 13.5 0.0 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NPV_P10 PF05531.12 OWF38804.1 - 0.058 13.9 0.2 0.058 13.9 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Na_sulph_symp PF00939.19 OWF38805.1 - 1.8e-96 324.1 20.3 2.3e-96 323.7 20.3 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF38805.1 - 6.2e-34 117.6 35.2 3.5e-21 75.7 0.4 3.4 3 1 1 4 4 4 3 Citrate transporter DUF4179 PF13786.6 OWF38805.1 - 0.89 10.1 2.5 74 3.9 2.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) GLE1 PF07817.13 OWF38806.1 - 5.6e-79 264.9 0.0 5.6e-79 264.9 0.0 2.8 2 1 0 2 2 2 1 GLE1-like protein DUF3287 PF11690.8 OWF38806.1 - 1.4 8.7 11.1 6.6 6.5 9.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) PTH2 PF01981.16 OWF38807.1 - 1.2e-43 148.2 0.1 1.4e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PTS_2-RNA PF01885.16 OWF38808.1 - 1.9e-10 41.1 0.0 4.7e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 RNA 2'-phosphotransferase, Tpt1 / KptA family LRR_6 PF13516.6 OWF38808.1 - 0.0025 17.7 11.0 7.9 6.8 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 OWF38808.1 - 0.01 16.2 14.1 0.56 10.7 0.5 4.6 1 1 5 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF38808.1 - 0.019 14.7 8.4 1.8 8.4 0.6 4.1 3 1 0 3 3 3 0 Leucine rich repeat PUFD PF16553.5 OWF38808.1 - 0.037 14.2 0.1 0.51 10.5 0.0 2.6 1 1 2 3 3 3 0 BCORL-PCGF1-binding domain DUF2095 PF09868.9 OWF38808.1 - 0.086 12.8 0.3 0.53 10.3 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2095) Otopetrin PF03189.13 OWF38809.1 - 1.5e-16 60.3 1.6 1.5e-16 60.3 1.6 2.9 1 1 2 3 3 3 2 Otopetrin Serglycin PF04360.12 OWF38809.1 - 0.13 12.2 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Serglycin Otopetrin PF03189.13 OWF38810.1 - 8.5e-21 74.3 6.5 8.5e-21 74.3 6.5 3.0 1 1 1 3 3 3 2 Otopetrin Serglycin PF04360.12 OWF38810.1 - 0.0094 15.9 0.3 0.068 13.1 0.0 2.1 2 0 0 2 2 2 1 Serglycin DUF2339 PF10101.9 OWF38810.1 - 0.019 13.6 13.6 0.99 7.9 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) Otopetrin PF03189.13 OWF38811.1 - 1.5e-19 70.2 7.0 1.5e-19 70.2 7.0 2.4 1 1 0 2 2 2 2 Otopetrin Serglycin PF04360.12 OWF38811.1 - 0.06 13.3 0.1 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Serglycin MCC-bdg_PDZ PF10506.9 OWF38812.1 - 1.2e-07 31.6 1.3 11 6.1 0.0 7.0 1 1 6 7 7 7 4 PDZ domain of MCC-2 bdg protein for Usher syndrome PKHD_C PF18331.1 OWF38812.1 - 9e-07 28.9 1.3 14 5.8 0.0 5.9 1 1 6 9 9 9 3 PKHD-type hydroxylase C-terminal domain Bd3614_N PF14442.6 OWF38812.1 - 0.052 13.9 10.7 41 4.6 0.1 4.2 1 1 1 2 2 2 0 Bd3614-like deaminase N-terminal NucS PF01939.16 OWF38812.1 - 0.13 11.6 2.2 7.9 5.8 0.1 3.4 1 1 3 4 4 4 0 Endonuclease NucS Cu2_monoox_C PF03712.15 OWF38813.1 - 1.7e-24 86.1 0.0 2.6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF38813.1 - 1.3e-08 35.1 0.0 2.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain bZIP_1 PF00170.21 OWF38816.1 - 0.0096 16.0 6.6 0.0096 16.0 6.6 6.5 4 2 3 7 7 7 3 bZIP transcription factor FtsL PF04999.13 OWF38816.1 - 0.93 9.5 12.3 0.26 11.3 4.2 3.2 2 1 0 2 2 2 0 Cell division protein FtsL CENP-F_leu_zip PF10473.9 OWF38816.1 - 3.7 7.6 49.4 0.98 9.4 20.4 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 OWF38816.1 - 4.8 5.7 24.6 1.2 7.6 1.6 2.4 2 1 0 2 2 2 0 Flagellar Assembly Protein A FliD_N PF02465.18 OWF38816.1 - 9.9 6.9 19.6 0.75 10.5 2.7 3.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SH3_2 PF07653.17 OWF38817.1 - 2.4e-31 107.2 0.0 3.2e-11 42.7 0.0 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 OWF38817.1 - 6e-27 93.3 0.8 2.6e-09 36.8 0.1 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 OWF38817.1 - 1.6e-16 59.6 0.1 4.6e-05 22.9 0.1 4.0 3 1 0 3 3 3 3 SH3 domain fn3 PF00041.21 OWF38817.1 - 2.2e-06 27.9 5.9 0.0098 16.2 2.0 4.2 3 1 0 3 3 3 2 Fibronectin type III domain MAD PF05557.13 OWF38817.1 - 0.026 12.9 16.5 0.051 11.9 16.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 OWF38817.1 - 0.063 12.2 15.5 0.13 11.1 15.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 OWF38817.1 - 0.14 12.4 19.1 0.026 14.8 8.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4091 PF13320.6 OWF38817.1 - 0.18 12.0 0.2 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) OmpH PF03938.14 OWF38817.1 - 0.25 11.7 11.7 0.74 10.2 11.7 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF812 PF05667.11 OWF38817.1 - 0.5 9.2 18.9 1.1 8.0 18.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 OWF38817.1 - 0.68 9.2 22.6 2.4 7.5 22.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 OWF38817.1 - 0.9 8.8 11.5 1.8 7.8 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OWF38817.1 - 1.9 8.0 10.9 4.8 6.7 10.9 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLZ PF16526.5 OWF38817.1 - 2.3 8.7 15.1 1.2 9.6 2.8 2.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 OWF38817.1 - 2.7 8.4 18.4 0.17 12.3 11.8 2.2 2 0 0 2 2 2 0 Fez1 Prefoldin PF02996.17 OWF38817.1 - 3.3 7.6 13.4 3.9 7.4 5.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.9 OWF38817.1 - 5.3 7.4 16.3 4.3 7.7 4.7 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uds1 PF15456.6 OWF38817.1 - 5.4 7.2 16.0 22 5.2 16.0 2.1 1 0 0 1 1 1 0 Up-regulated During Septation DUF724 PF05266.14 OWF38817.1 - 7.5 6.3 13.6 19 5.0 12.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) 7tm_1 PF00001.21 OWF38818.1 - 7e-30 104.2 17.8 8.6e-30 103.9 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BID PF06393.11 OWF38819.1 - 0.013 15.0 0.4 0.031 13.8 0.1 1.7 2 1 0 2 2 2 0 BH3 interacting domain (BID) C2 PF00168.30 OWF38820.1 - 1.4e-37 128.1 0.0 1.8e-20 73.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 OWF38820.1 - 1.1e-12 48.3 2.0 2.3e-12 47.1 2.0 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger PDZ_6 PF17820.1 OWF38820.1 - 7e-10 38.6 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF38820.1 - 3.7e-09 36.8 0.5 8.7e-09 35.6 0.5 1.6 1 0 0 1 1 1 1 PDZ domain Cytochrome_C7 PF14522.6 OWF38820.1 - 0.17 11.9 5.4 0.17 11.9 2.7 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Basic PF01586.16 OWF38820.1 - 0.37 12.0 5.5 4.1 8.6 5.5 2.9 1 0 0 1 1 1 0 Myogenic Basic domain KID PF02524.14 OWF38821.1 - 2.2e-06 26.8 1.2 78 4.1 0.0 6.9 8 0 0 8 8 8 0 KID repeat UVR PF02151.19 OWF38821.1 - 0.0015 18.2 3.1 64 3.5 0.0 5.9 7 0 0 7 7 7 0 UvrB/uvrC motif Colipase-like PF15083.6 OWF38821.1 - 0.014 15.5 0.6 0.022 14.9 0.6 1.4 1 0 0 1 1 1 0 Colipase-like MP PF01107.18 OWF38821.1 - 0.1 12.1 0.5 9.4 5.7 0.1 2.0 1 1 1 2 2 2 0 Viral movement protein (MP) DUF1682 PF07946.14 OWF38822.1 - 0.033 13.4 14.4 0.051 12.8 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) YjbH PF06082.11 OWF38822.1 - 0.38 9.5 5.4 0.51 9.1 5.4 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF3340 PF11818.8 OWF38822.1 - 5.9 7.0 18.0 12 6.0 18.0 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Elongin_A PF06881.11 OWF38823.1 - 5.8e-21 75.0 0.4 5.8e-21 75.0 0.4 6.5 7 3 1 8 8 8 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 OWF38823.1 - 5.3e-12 45.6 0.7 2.3e-11 43.5 0.1 2.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain IBR PF01485.21 OWF38824.1 - 2.5e-08 34.0 39.1 3.3e-08 33.6 11.1 3.8 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OWF38824.1 - 0.042 14.2 36.7 2.3 8.6 11.5 4.6 3 2 2 5 5 5 0 Ring finger domain IBR PF01485.21 OWF38825.1 - 2.5e-10 40.4 35.3 1.4e-07 31.7 13.9 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 OWF38825.1 - 0.057 13.2 1.0 0.057 13.2 1.0 5.2 5 0 0 5 5 5 0 zinc-ribbon domain SAM_2 PF07647.17 OWF38826.1 - 1.4e-06 28.3 0.1 3.9e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CABIT PF12736.7 OWF38826.1 - 2.5e-06 27.0 0.0 6.2e-05 22.4 0.0 2.2 1 1 0 2 2 2 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.30 OWF38826.1 - 9.2e-06 26.0 0.4 1.7e-05 25.1 0.4 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1659 PF07872.11 OWF38826.1 - 2 8.2 5.8 4.3 7.1 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1659) PRP3 PF08572.10 OWF38827.1 - 9.5e-78 261.0 11.4 9.5e-78 261.0 11.4 2.6 3 1 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OWF38827.1 - 1.2e-44 151.9 2.6 1.2e-44 151.9 2.6 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) PWI PF01480.17 OWF38827.1 - 0.00045 20.5 0.9 0.0015 18.8 0.1 2.3 2 0 0 2 2 2 1 PWI domain TGFb_propeptide PF00688.18 OWF38828.1 - 1e-56 192.4 0.0 1.3e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 OWF38828.1 - 1.4e-31 109.5 0.0 3.1e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain SNF PF00209.18 OWF38829.1 - 2.1e-48 165.3 38.4 2.6e-28 99.0 19.5 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family 7tm_1 PF00001.21 OWF38830.1 - 2.1e-27 96.1 13.7 3.6e-27 95.4 13.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF38830.1 - 1.1e-06 28.1 5.9 1.1e-06 28.1 5.9 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF38831.1 - 1.3e-24 87.0 10.4 1.6e-24 86.6 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LysE PF01810.18 OWF38831.1 - 7.1e-05 22.3 1.2 0.05 13.1 0.1 2.7 3 0 0 3 3 3 2 LysE type translocator 7tm_4 PF13853.6 OWF38831.1 - 9.3e-05 22.3 6.6 9.3e-05 22.3 6.6 2.5 2 1 0 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 OWF38832.1 - 3e-29 102.1 14.5 3.9e-29 101.8 14.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF38832.1 - 0.0015 17.9 24.1 0.29 10.4 24.1 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw COX2_TM PF02790.15 OWF38832.1 - 0.0044 17.1 3.7 0.84 9.8 0.1 3.4 3 0 0 3 3 3 2 Cytochrome C oxidase subunit II, transmembrane domain Glutaminase PF04960.15 OWF38833.1 - 6.7e-21 74.7 0.1 1.1e-20 74.0 0.1 1.3 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 OWF38833.1 - 1.1e-11 45.1 0.0 2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38833.1 - 6.9e-09 36.1 0.0 1.6e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF38833.1 - 9.6e-09 35.3 0.2 1.2e-06 28.7 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF38833.1 - 7.3e-06 25.9 0.0 0.00029 21.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OWF38833.1 - 2e-05 24.8 0.0 0.013 15.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat NAD_binding_5 PF07994.12 OWF38834.1 - 5.1e-141 469.7 0.0 6.2e-141 469.4 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OWF38834.1 - 1.4e-47 160.4 0.1 2.8e-47 159.5 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Sigma_reg_N PF13800.6 OWF38834.1 - 0.22 11.8 3.5 0.38 11.1 0.6 2.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Peptidase_M90 PF06167.12 OWF38835.1 - 0.55 9.8 3.9 19 4.7 3.9 2.3 1 1 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 adh_short PF00106.25 OWF38836.1 - 1.9e-40 138.4 0.0 2.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38836.1 - 1.2e-24 87.2 0.0 1.7e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OWF38836.1 - 0.00022 20.7 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OWF38836.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain BTB PF00651.31 OWF38837.1 - 1e-20 74.0 0.0 1.6e-19 70.2 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF38837.1 - 7e-11 42.2 2.8 2.1e-10 40.6 0.8 2.6 2 1 0 2 2 2 1 BTB And C-terminal Kelch Na_sulph_symp PF00939.19 OWF38838.1 - 5.2e-89 299.4 30.7 6.2e-89 299.2 30.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF38838.1 - 1.3e-40 139.5 45.8 1.8e-38 132.5 19.5 2.3 1 1 1 2 2 2 2 Citrate transporter PheRS_DBD2 PF18554.1 OWF38838.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Na_sulph_symp PF00939.19 OWF38839.1 - 1.3e-88 298.2 24.7 1.5e-88 297.9 24.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF38839.1 - 3.1e-32 112.0 23.9 1.2e-20 74.0 5.4 3.3 2 1 1 3 3 3 3 Citrate transporter Cu2_monoox_C PF03712.15 OWF38842.1 - 7.4e-45 152.3 0.0 1.4e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF38842.1 - 3.5e-38 130.8 0.3 6.6e-38 129.9 0.3 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 OWF38842.1 - 2.1e-27 95.8 1.0 4.8e-27 94.6 0.4 2.0 2 0 0 2 2 2 1 DOMON domain Alpha_GJ PF03229.13 OWF38842.1 - 0.021 15.4 4.5 0.049 14.2 4.5 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Na_sulph_symp PF00939.19 OWF38843.1 - 4e-18 65.7 8.9 4.7e-18 65.5 8.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF38843.1 - 5.3e-05 22.6 12.7 5.9e-05 22.4 12.7 1.1 1 0 0 1 1 1 1 Citrate transporter Glutaminase PF04960.15 OWF38844.1 - 5e-121 403.3 0.0 7.8e-121 402.6 0.0 1.3 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 OWF38844.1 - 3.6e-26 91.3 0.7 8e-26 90.2 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain Ank_2 PF12796.7 OWF38844.1 - 4.5e-11 43.2 0.0 1.1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF38844.1 - 9.6e-09 35.6 0.1 5.2e-05 23.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF38844.1 - 2.5e-07 30.9 0.1 3.8e-06 27.1 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF38844.1 - 3.3e-07 30.5 0.1 0.0005 20.4 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 OWF38844.1 - 0.00012 22.2 0.0 0.0047 17.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat 7tm_1 PF00001.21 OWF38845.1 - 5.7e-30 104.5 12.1 7.7e-30 104.1 12.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3285 PF11688.8 OWF38845.1 - 0.0041 17.0 0.4 0.023 14.6 0.4 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3285) Glyco_hydro_63 PF03200.16 OWF38845.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Cadherin_C_2 PF16492.5 OWF38845.1 - 0.14 12.9 8.0 4 8.2 0.1 3.4 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF4834 PF16118.5 OWF38845.1 - 0.62 11.1 0.0 0.62 11.1 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3810 PF12725.7 OWF38845.1 - 3.1 7.1 9.6 0.15 11.4 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Acetyltransf_10 PF13673.7 OWF38846.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF38846.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Galactosyl_T PF01762.21 OWF38847.1 - 1.6e-39 135.7 0.0 2.5e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Med30 PF11315.8 OWF38849.1 - 1.3e-44 151.9 1.9 1.6e-44 151.6 1.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 APG17 PF04108.12 OWF38849.1 - 0.01 15.0 0.2 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 KxDL PF10241.9 OWF38849.1 - 0.024 14.9 0.2 2.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF4810 PF16068.5 OWF38849.1 - 0.025 15.1 0.3 0.15 12.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) Gp-FAR-1 PF05823.12 OWF38849.1 - 0.028 14.8 0.4 0.089 13.2 0.2 1.8 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2533 PF10752.9 OWF38849.1 - 0.048 14.1 0.1 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Prefoldin PF02996.17 OWF38849.1 - 0.14 12.1 1.6 6.6 6.7 0.1 2.9 3 0 0 3 3 3 0 Prefoldin subunit Elf4 PF07011.11 OWF38849.1 - 0.26 11.2 1.2 0.71 9.8 0.3 2.1 2 0 0 2 2 2 0 Early Flowering 4 domain WD40 PF00400.32 OWF38850.1 - 1.8e-07 31.7 5.9 0.012 16.4 0.2 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-C2H2 PF00096.26 OWF38850.1 - 0.051 14.1 3.4 2.4 8.8 0.1 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF38850.1 - 0.24 12.3 8.9 0.82 10.7 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 OWF38850.1 - 0.81 9.3 3.3 11 5.8 0.6 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Desulfoferrod_N PF06397.12 OWF38850.1 - 0.94 9.2 3.1 0.59 9.8 0.5 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF4428 PF14471.6 OWF38850.1 - 7.6 6.5 7.8 1.8 8.6 0.3 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) Pepdidase_M14_N PF18027.1 OWF38851.1 - 1.7e-15 57.3 0.1 1.1e-14 54.7 0.1 2.4 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 OWF38851.1 - 2.2e-14 54.0 0.0 5.8e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase PHO4 PF01384.20 OWF38853.1 - 6.4e-117 390.4 8.5 8.7e-117 389.9 8.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family HHA PF05321.11 OWF38854.1 - 0.37 11.1 10.6 8.1 6.8 0.4 5.1 3 3 2 5 5 5 0 Haemolysin expression modulating protein Astacin PF01400.24 OWF38855.1 - 4.1e-50 170.1 0.0 5.6e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OWF38855.1 - 0.00093 19.1 0.0 0.0025 17.7 0.0 1.6 1 1 0 1 1 1 1 Matrixin LDB19 PF13002.7 OWF38855.1 - 0.065 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like MFS_1 PF07690.16 OWF38856.1 - 4e-28 98.3 31.7 4.8e-28 98.1 31.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Plasmod_dom_1 PF09715.10 OWF38856.1 - 0.058 13.5 0.5 1 9.5 0.0 2.9 2 1 1 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF4796 PF16044.5 OWF38857.1 - 4.7e-60 202.4 0.7 5.4e-60 202.2 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) Frizzled PF01534.17 OWF38858.1 - 4.3e-87 292.2 18.1 6.1e-87 291.7 18.1 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 OWF38858.1 - 2.1e-11 44.4 4.6 4.7e-11 43.3 4.6 1.6 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.24 OWF38858.1 - 3.6e-06 26.4 8.4 9.6e-06 25.1 8.4 1.7 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 OWF38858.1 - 0.00069 18.8 6.9 0.00069 18.8 6.9 2.4 1 1 0 2 2 2 1 Slime mold cyclic AMP receptor STE3 PF02076.15 OWF38858.1 - 0.0019 17.5 10.0 0.0043 16.3 10.0 1.5 1 0 0 1 1 1 1 Pheromone A receptor Viral_Beta_CD PF04530.12 OWF38858.1 - 0.9 9.8 4.4 0.82 10.0 0.1 2.8 3 0 0 3 3 3 0 Viral Beta C/D like family RRT14 PF17075.5 OWF38858.1 - 1.9 8.6 10.8 0.1 12.7 1.3 2.7 3 0 0 3 3 3 0 Regular of rDNA transcription protein 14 tRNA_int_endo PF01974.17 OWF38859.1 - 6.9e-20 70.9 0.0 1.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OWF38859.1 - 4e-10 39.2 0.6 1.8e-06 27.5 0.1 2.8 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF968 PF06147.11 OWF38860.1 - 0.045 14.0 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF968) MRP-S23 PF10484.9 OWF38860.1 - 0.65 10.3 4.2 0.52 10.6 1.9 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 Reprolysin PF01421.19 OWF38861.1 - 2.2e-18 66.9 3.3 1.3e-17 64.4 3.3 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 OWF38861.1 - 4.6e-14 53.0 0.5 4.6e-14 53.0 0.5 2.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 ADAM_CR_2 PF17771.1 OWF38861.1 - 1e-12 48.4 6.0 1e-12 48.4 6.0 2.6 3 0 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin_2 PF13574.6 OWF38861.1 - 4.6e-12 46.2 0.2 4.6e-12 46.2 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF38861.1 - 5.1e-09 36.7 0.6 5.1e-09 36.7 0.6 3.1 3 1 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF38861.1 - 8.7e-06 25.5 0.0 8.7e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Amnionless PF14828.6 OWF38861.1 - 0.017 13.9 3.2 0.029 13.2 3.2 1.3 1 0 0 1 1 1 0 Amnionless Bystin PF05291.11 OWF38862.1 - 1.5e-139 464.2 4.0 1.5e-139 464.2 4.0 1.4 2 0 0 2 2 2 1 Bystin NHS PF15273.6 OWF38862.1 - 0.15 11.2 2.1 0.2 10.7 2.1 1.1 1 0 0 1 1 1 0 NHS-like DUF789 PF05623.12 OWF38862.1 - 1.1 8.9 5.4 2.3 7.8 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF789) adh_short PF00106.25 OWF38863.1 - 3.6e-51 173.4 0.2 4.4e-51 173.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF38863.1 - 1.3e-33 116.5 0.4 1.7e-33 116.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF38863.1 - 1.9e-10 40.9 0.1 2.7e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OWF38863.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EF-hand_1 PF00036.32 OWF38864.1 - 4.4e-11 41.5 3.6 3.4e-08 32.5 1.6 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 OWF38864.1 - 1.6e-10 41.3 2.1 6.1e-07 29.8 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF38864.1 - 4e-10 38.8 9.2 2.9e-08 33.0 1.1 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OWF38864.1 - 3.6e-05 23.5 7.6 0.0015 18.3 0.5 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF38864.1 - 5.4e-05 22.5 1.6 5.4e-05 22.5 1.6 2.6 3 0 0 3 3 3 1 EF hand DDE_Tnp_IS66_C PF13817.6 OWF38864.1 - 0.0052 17.0 0.1 0.15 12.3 0.1 2.4 2 0 0 2 2 2 1 IS66 C-terminal element SPARC_Ca_bdg PF10591.9 OWF38864.1 - 0.072 13.4 0.4 0.13 12.6 0.4 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Bac_RepA_C PF18008.1 OWF38865.1 - 0.046 14.1 0.1 0.098 13.0 0.1 1.5 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain LKAAEAR PF15478.6 OWF38866.1 - 4.9e-44 149.9 10.7 6.2e-44 149.6 10.7 1.0 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif AMP_N PF05195.16 OWF38867.1 - 0.022 14.5 0.0 0.063 13.0 0.0 1.8 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF641 PF04859.12 OWF38867.1 - 0.023 15.0 3.8 0.023 15.0 3.8 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Octopine_DH PF02317.17 OWF38867.1 - 0.043 13.9 4.1 0.26 11.3 4.1 2.1 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF4407 PF14362.6 OWF38867.1 - 0.15 11.4 8.5 0.3 10.4 8.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 OWF38867.1 - 0.29 11.2 21.4 0.21 11.7 14.7 3.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Cep57_MT_bd PF06657.13 OWF38867.1 - 2.1 8.8 13.6 0.88 10.1 1.6 3.0 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PhoU PF01895.19 OWF38867.1 - 2.8 8.4 10.1 0.52 10.8 4.1 2.5 1 1 0 2 2 2 0 PhoU domain zf-C2H2_4 PF13894.6 OWF38868.1 - 3e-14 52.5 48.8 0.0013 19.4 2.1 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF38868.1 - 1.7e-12 47.1 45.0 0.00012 22.4 2.3 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF38868.1 - 4.8e-10 39.4 37.6 1.7e-06 28.2 0.3 6.7 7 0 0 7 7 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF38868.1 - 3.2e-06 27.3 20.1 0.0082 16.4 0.2 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF38868.1 - 0.0015 18.8 24.9 0.086 13.3 0.4 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF38868.1 - 0.0053 17.0 3.3 0.0053 17.0 3.3 4.3 2 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding DUF459 PF04311.13 OWF38868.1 - 0.024 13.6 0.1 0.051 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF459) zf-H2C2_5 PF13909.6 OWF38868.1 - 0.065 13.0 0.1 0.065 13.0 0.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 OWF38868.1 - 0.095 13.4 0.1 0.095 13.4 0.1 5.8 3 1 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 OWF38868.1 - 0.1 13.1 25.8 2.2 8.8 3.2 5.9 3 2 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger ADK_lid PF05191.14 OWF38868.1 - 0.15 12.0 6.0 5 7.2 3.0 3.7 2 1 0 2 2 2 0 Adenylate kinase, active site lid HNH_5 PF14279.6 OWF38868.1 - 0.35 10.7 11.2 2.6 8.0 0.3 4.9 3 2 1 4 4 4 0 HNH endonuclease PHD_Oberon PF07227.11 OWF38868.1 - 0.76 9.7 16.3 0.39 10.6 5.5 3.0 2 1 1 3 3 3 0 PHD - plant homeodomain finger protein zinc_ribbon_15 PF17032.5 OWF38868.1 - 1.3 9.8 17.9 14 6.5 0.6 4.4 2 1 1 3 3 3 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 OWF38868.1 - 2.9 8.1 19.6 8.4 6.6 0.1 4.9 4 1 0 4 4 4 0 Zinc ribbon domain CAC1F_C PF16885.5 OWF38868.1 - 5.4 6.6 11.6 1 9.0 3.3 2.3 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Nop14 PF04147.12 OWF38868.1 - 5.4 5.1 16.5 8.8 4.4 16.5 1.2 1 0 0 1 1 1 0 Nop14-like family Glycos_transf_2 PF00535.26 OWF38869.1 - 3.2e-24 85.6 0.0 6.2e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 OWF38869.1 - 1.2e-09 37.7 0.0 2.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF38869.1 - 4.7e-06 26.7 0.0 1.2e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OWF38869.1 - 1.1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OWF38869.1 - 0.02 14.8 0.2 0.053 13.4 0.2 1.6 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OWF38869.1 - 0.14 11.6 0.0 0.7 9.4 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 Ricin_B_lectin PF00652.22 OWF38869.1 - 0.2 11.9 0.1 0.36 11.1 0.1 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 OWF38870.1 - 1.7e-24 86.5 0.0 3.2e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 OWF38870.1 - 3e-10 39.6 0.0 6.7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF38870.1 - 5.9e-08 32.9 0.0 9.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OWF38870.1 - 2.6e-06 27.1 0.0 5.9e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OWF38870.1 - 0.00017 21.5 0.4 0.00044 20.2 0.4 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OWF38870.1 - 0.11 12.0 0.0 0.56 9.7 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 EF-hand_6 PF13405.6 OWF38872.1 - 1.5e-14 52.6 5.1 0.00065 19.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OWF38872.1 - 2e-11 44.2 5.7 8.3e-07 29.4 0.3 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF38872.1 - 1.4e-10 39.9 7.1 0.0039 16.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF38872.1 - 1.4e-07 31.2 6.3 0.032 14.1 0.0 4.0 3 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF38872.1 - 4.5e-07 29.1 8.6 0.0012 18.3 0.0 3.6 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 OWF38872.1 - 0.00041 20.6 0.2 0.48 10.8 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 OWF38872.1 - 0.04 13.9 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TerB Excalibur PF05901.11 OWF38872.1 - 2.8 8.7 5.0 7.6 7.2 0.1 2.8 2 1 0 3 3 3 0 Excalibur calcium-binding domain MCPsignal PF00015.21 OWF38873.1 - 0.00035 20.4 7.7 0.0055 16.5 1.1 2.1 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Sigma_1s PF02454.16 OWF38873.1 - 0.0032 17.4 0.3 0.42 10.6 0.0 2.3 1 1 1 2 2 2 1 Sigma 1s protein PI3K_P85_iSH2 PF16454.5 OWF38873.1 - 0.0073 15.9 3.0 1.9 8.0 0.1 3.5 1 1 3 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Collagen_mid PF15984.5 OWF38873.1 - 0.012 15.4 2.8 0.012 15.3 2.1 1.3 1 1 0 1 1 1 0 Bacterial collagen, middle region DUF4872 PF16169.5 OWF38873.1 - 0.029 14.1 0.0 3.5 7.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4872) EzrA PF06160.12 OWF38873.1 - 0.037 12.2 3.3 0.043 12.0 1.6 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 OWF38873.1 - 0.044 12.7 7.9 0.095 11.7 3.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 WXG100 PF06013.12 OWF38873.1 - 0.059 13.6 0.1 15 5.9 0.0 3.4 2 2 2 4 4 4 0 Proteins of 100 residues with WXG V-SNARE_C PF12352.8 OWF38873.1 - 0.077 13.3 3.8 1.3 9.4 0.2 3.2 2 2 2 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus Exonuc_VII_L PF02601.15 OWF38873.1 - 0.079 12.5 6.2 0.13 11.8 6.2 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit FtsL PF04999.13 OWF38873.1 - 0.14 12.2 5.3 0.59 10.2 0.2 2.9 1 1 2 3 3 3 0 Cell division protein FtsL Bacillus_HBL PF05791.11 OWF38873.1 - 0.16 11.8 7.6 0.1 12.4 0.7 2.7 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Mce4_CUP1 PF11887.8 OWF38873.1 - 0.16 11.4 5.1 1.2 8.5 0.4 2.0 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative IFT20 PF14931.6 OWF38873.1 - 0.22 11.7 18.0 0.9 9.7 0.4 4.2 1 1 3 4 4 4 0 Intraflagellar transport complex B, subunit 20 DUF2884 PF11101.8 OWF38873.1 - 0.4 10.2 5.7 0.29 10.6 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF1664 PF07889.12 OWF38873.1 - 0.41 10.7 6.1 0.95 9.5 1.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TfuA PF07812.12 OWF38873.1 - 0.45 10.3 2.7 1.9 8.2 0.3 2.5 2 1 1 3 3 3 0 TfuA-like protein CortBP2 PF09727.9 OWF38873.1 - 0.45 10.4 2.8 4.1 7.3 1.0 2.1 1 1 1 2 2 2 0 Cortactin-binding protein-2 Nre_C PF04895.12 OWF38873.1 - 0.78 9.7 8.0 17 5.3 0.5 3.0 1 1 2 3 3 3 0 Archaeal Nre, C-terminal DUF3347 PF11827.8 OWF38873.1 - 2 8.6 12.8 26 4.9 12.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) DUF948 PF06103.11 OWF38873.1 - 2.7 8.3 11.0 4.3e+02 1.2 11.0 3.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PTH2 PF01981.16 OWF38875.1 - 8.1e-36 122.9 0.1 1.7e-35 121.8 0.0 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 UBA PF00627.31 OWF38875.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain eIF-5a PF01287.20 OWF38875.1 - 0.31 11.2 0.2 0.31 11.2 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold HECT PF00632.25 OWF38876.1 - 8e-62 209.5 0.0 1.3e-61 208.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.8 OWF38876.1 - 1.1e-30 105.0 3.3 1.1e-30 105.0 3.3 3.0 3 0 0 3 3 3 1 E3 ubiquitin ligase EDD PABP PF00658.18 OWF38876.1 - 2.1e-19 69.5 0.0 4.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Translin PF01997.16 OWF38877.1 - 1.4e-53 181.9 1.1 1.7e-53 181.7 1.1 1.0 1 0 0 1 1 1 1 Translin family ATP-synt_D PF01813.17 OWF38877.1 - 0.021 14.6 1.8 0.65 9.8 0.1 2.3 2 1 0 2 2 2 0 ATP synthase subunit D DDRGK PF09756.9 OWF38877.1 - 0.029 14.0 0.4 0.055 13.1 0.4 1.5 1 1 0 1 1 1 0 DDRGK domain Med30 PF11315.8 OWF38877.1 - 0.03 14.5 1.9 0.05 13.8 1.1 1.8 2 0 0 2 2 2 0 Mediator complex subunit 30 GTP-bdg_M PF16360.5 OWF38877.1 - 1.3 9.6 4.5 49 4.6 2.2 2.8 3 1 0 3 3 3 0 GTP-binding GTPase Middle Region Plasmodium_HRP PF05403.11 OWF38878.1 - 0.02 14.7 1.6 0.27 11.0 0.2 2.8 2 1 0 3 3 3 0 Plasmodium histidine-rich protein (HRPII/III) bZIP_2 PF07716.15 OWF38879.1 - 6.5e-07 29.3 4.6 1.2e-06 28.5 4.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF38879.1 - 0.00025 21.1 4.9 0.00025 21.1 4.9 1.8 2 0 0 2 2 2 1 bZIP transcription factor Ribosomal_L19e PF01280.20 OWF38879.1 - 0.21 11.6 5.8 1.4 9.0 6.6 1.8 1 1 1 2 2 2 0 Ribosomal protein L19e Peptidase_C1 PF00112.23 OWF38880.1 - 1.3e-67 228.1 6.4 1.6e-67 227.8 6.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 OWF38880.1 - 4.8e-10 39.2 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 OWF38880.1 - 0.0046 15.8 1.4 0.25 10.1 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 OWF38881.1 - 5.1e-66 222.9 6.0 6.4e-66 222.6 6.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 OWF38881.1 - 1.6e-12 47.1 0.0 3.8e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 OWF38881.1 - 0.0027 16.6 0.3 0.41 9.3 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family PMP22_Claudin PF00822.20 OWF38882.1 - 0.00039 20.3 13.4 0.00097 19.1 13.5 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2070 PF09843.9 OWF38882.1 - 0.061 11.6 2.7 0.071 11.4 2.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_2_1 PF04971.12 OWF38882.1 - 0.33 11.0 8.3 0.056 13.5 1.6 2.8 3 0 0 3 3 3 0 Bacteriophage P21 holin S ACR_tran PF00873.19 OWF38882.1 - 0.35 8.5 3.0 0.4 8.3 3.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TMEM208_SND2 PF05620.11 OWF38882.1 - 1.2 8.9 4.6 0.53 10.0 1.5 1.8 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Claudin_2 PF13903.6 OWF38882.1 - 3.1 7.5 23.7 62 3.3 0.2 3.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.9 OWF38882.1 - 3.4 6.3 9.4 6.8 5.3 8.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5090 PF17009.5 OWF38882.1 - 6.7 6.6 8.8 7.1 6.5 6.9 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5090) ShK PF01549.24 OWF38884.1 - 0.042 14.4 6.6 0.042 14.4 6.6 7.2 7 1 0 7 7 7 0 ShK domain-like Claudin_2 PF13903.6 OWF38885.1 - 1.4e-14 54.3 11.1 2e-14 53.8 11.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF38885.1 - 2.1e-05 24.5 12.1 0.00014 21.9 12.1 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Clc-like PF07062.12 OWF38885.1 - 0.00033 20.2 12.1 0.014 14.8 12.1 2.2 1 1 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 OWF38886.1 - 8.2e-14 51.8 10.1 1e-13 51.5 10.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 OWF38886.1 - 0.00036 20.1 16.1 0.03 13.8 13.4 2.5 1 1 1 2 2 2 1 Clc-like Claudin_3 PF06653.11 OWF38886.1 - 0.002 18.1 11.6 0.0086 16.0 11.6 1.9 1 1 0 1 1 1 1 Tight junction protein, Claudin-like GSG-1 PF07803.11 OWF38886.1 - 0.0057 16.6 0.2 0.018 15.0 0.2 1.8 1 1 0 1 1 1 1 GSG1-like protein L_HMGIC_fpl PF10242.9 OWF38886.1 - 0.065 13.4 12.8 0.028 14.6 9.9 1.8 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein SUR7 PF06687.12 OWF38886.1 - 0.24 11.0 14.2 2.7 7.6 8.6 2.7 2 2 0 2 2 2 0 SUR7/PalI family COX7a PF02238.15 OWF38886.1 - 0.7 10.3 0.0 0.7 10.3 0.0 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII DUF2070 PF09843.9 OWF38886.1 - 0.97 7.6 8.3 0.11 10.8 4.3 1.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 OWF38887.1 - 2.1e-64 217.7 24.1 2.9e-61 207.4 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF38887.1 - 2.2e-10 40.0 21.3 1.9e-09 36.9 6.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter BT1 PF03092.16 OWF38887.1 - 0.023 13.0 6.6 0.14 10.3 0.0 3.0 3 0 0 3 3 3 0 BT1 family HRG PF16954.5 OWF38887.1 - 0.046 14.1 2.2 0.26 11.7 0.2 3.4 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene MFS_1 PF07690.16 OWF38888.1 - 9.2e-53 179.4 23.6 1.2e-52 179.0 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF38888.1 - 1.5e-07 30.7 7.3 1.5e-07 30.7 7.3 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter CENP-O PF09496.10 OWF38889.1 - 3.3e-08 33.8 0.3 3.3e-08 33.8 0.3 2.3 1 1 0 2 2 2 1 Cenp-O kinetochore centromere component E2F_CC-MB PF16421.5 OWF38889.1 - 6.3 7.2 10.6 0.24 11.8 3.7 2.3 3 1 1 4 4 4 0 E2F transcription factor CC-MB domain AdoMet_MTase PF07757.13 OWF38890.1 - 3.8e-42 143.1 0.1 6.8e-42 142.3 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 OWF38890.1 - 0.0034 17.4 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF38890.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 OWF38890.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Claudin_2 PF13903.6 OWF38891.1 - 3.9e-11 43.1 20.6 6.4e-05 22.8 0.0 3.0 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF38891.1 - 6.2e-07 29.4 10.8 7.2e-06 26.0 10.8 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2518 PF10726.9 OWF38891.1 - 0.68 9.6 8.3 0.32 10.6 4.1 2.1 2 0 0 2 2 2 0 Protein of function (DUF2518) Claudin_3 PF06653.11 OWF38891.1 - 8.7 6.3 15.9 70 3.3 15.8 2.2 1 1 0 1 1 1 0 Tight junction protein, Claudin-like GATA PF00320.27 OWF38892.1 - 4.8e-30 102.9 16.8 2.1e-15 56.0 6.4 2.4 2 0 0 2 2 2 2 GATA zinc finger GATA-N PF05349.12 OWF38892.1 - 5e-10 40.0 21.4 5e-10 40.0 21.4 2.3 2 1 0 2 2 2 1 GATA-type transcription activator, N-terminal TF_Zn_Ribbon PF08271.12 OWF38892.1 - 3.2e-05 23.4 7.1 0.051 13.1 1.8 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 OWF38892.1 - 0.0027 17.8 1.0 1.1 9.4 0.1 2.3 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 OWF38892.1 - 0.025 14.7 2.3 1.9 8.7 0.2 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 OWF38892.1 - 0.11 12.7 4.4 0.97 9.6 0.2 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 OWF38892.1 - 0.12 12.4 3.0 12 6.0 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon Cytochrome_C7 PF14522.6 OWF38892.1 - 0.17 11.9 1.0 0.35 10.9 0.2 1.9 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c eIF-5_eIF-2B PF01873.17 OWF38892.1 - 0.73 9.7 5.1 7.3 6.5 1.1 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 OWF38892.1 - 0.74 9.8 6.5 3.2 7.7 0.6 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.12 OWF38892.1 - 1.3 9.4 8.9 0.78 10.1 1.5 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2387 PF09526.10 OWF38892.1 - 1.7 8.8 3.8 65 3.8 0.1 3.1 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.13 OWF38892.1 - 3.8 7.6 6.2 12 6.0 0.1 2.7 3 0 0 3 3 2 0 Transcription elongation factor Elf1 like Cytochrom_c3_2 PF14537.6 OWF38892.1 - 7.5 7.1 5.8 0.68 10.4 0.3 2.0 2 1 0 2 2 2 0 Cytochrome c3 CoiA PF06054.11 OWF38893.1 - 0.052 12.7 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Competence protein CoiA-like family Med31 PF05669.12 OWF38893.1 - 0.28 11.2 6.0 12 6.0 6.0 2.9 1 1 0 1 1 1 0 SOH1 RST PF12174.8 OWF38893.1 - 0.65 10.0 5.0 46 4.0 0.1 4.9 2 2 2 6 6 6 0 RCD1-SRO-TAF4 (RST) plant domain DUF1852 PF08908.11 OWF38893.1 - 3.7 6.4 5.0 12 4.8 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1852) PKcGMP_CC PF16808.5 OWF38894.1 - 0.034 14.0 0.3 0.034 14.0 0.3 7.0 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 OWF38894.1 - 0.042 14.2 2.9 0.042 14.2 2.9 7.1 1 1 5 7 7 7 0 Csm1 N-terminal domain Bap31_Bap29_C PF18035.1 OWF38894.1 - 0.062 13.3 0.0 0.062 13.3 0.0 4.4 5 0 0 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain Sas6_CC PF18594.1 OWF38894.1 - 0.9 9.4 9.7 8 6.3 1.5 3.5 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Inhibitor_Mig-6 PF11555.8 OWF38895.1 - 0.14 12.3 6.2 0.54 10.4 6.2 2.0 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 E2F_CC-MB PF16421.5 OWF38896.1 - 8.8e-26 90.1 0.6 5.6e-25 87.5 0.2 2.2 2 1 0 2 2 2 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 OWF38897.1 - 1.9e-25 88.7 0.3 4.2e-25 87.6 0.3 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OWF38897.1 - 2.1e-06 28.0 0.7 4.8e-06 26.8 0.3 1.8 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain TrmB PF01978.19 OWF38897.1 - 0.058 13.3 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Big_3_2 PF12245.8 OWF38898.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain CARD PF00619.21 OWF38899.1 - 5.1e-22 77.7 3.1 4.2e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 Caspase recruitment domain CARD_2 PF16739.5 OWF38899.1 - 2.6e-11 43.4 0.2 6e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 Caspase recruitment domain TPR_12 PF13424.6 OWF38899.1 - 0.00068 19.9 3.1 0.12 12.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF38899.1 - 0.012 15.7 2.6 28 5.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sulfotransfer_1 PF00685.27 OWF38900.1 - 1.1e-40 139.8 0.1 7.5e-39 133.8 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF38900.1 - 7.6e-06 26.5 0.0 1.2e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF38901.1 - 1.3e-45 156.0 0.8 6.4e-44 150.4 0.8 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF38901.1 - 1.4e-07 32.2 0.0 2.7e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family RPE65 PF03055.15 OWF38902.1 - 3.4e-79 267.2 2.0 4e-79 267.0 2.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FAM221 PF14753.6 OWF38903.1 - 3.2e-90 301.0 5.3 4.1e-90 300.6 5.3 1.1 1 0 0 1 1 1 1 Protein FAM221A/B DUF674 PF05056.12 OWF38903.1 - 0.97 8.2 3.6 1.4 7.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) 7tm_1 PF00001.21 OWF38904.1 - 2.6e-20 72.8 22.9 4.4e-20 72.1 22.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STI1 PF17830.1 OWF38905.1 - 3.8e-13 49.2 14.0 1.7e-09 37.4 0.1 3.1 4 0 0 4 4 4 2 STI1 domain DEAD PF00270.29 OWF38906.1 - 6.2e-47 159.6 3.7 8.2e-47 159.2 0.0 2.7 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF38906.1 - 3.7e-25 88.4 0.2 9.7e-24 83.9 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OWF38906.1 - 1.3e-15 57.4 0.2 2.4e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 OWF38906.1 - 0.36 11.1 1.9 0.83 9.9 0.7 2.3 2 1 0 2 2 2 0 AAA domain BUD22 PF09073.10 OWF38906.1 - 1.4 8.2 27.5 2.1 7.6 27.5 1.2 1 0 0 1 1 1 0 BUD22 B-block_TFIIIC PF04182.12 OWF38907.1 - 0.33 11.1 2.4 0.78 9.9 0.3 2.0 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC STAR_dimer PF16544.5 OWF38908.1 - 6.9e-26 89.6 1.0 1.7e-25 88.4 1.0 1.7 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 OWF38908.1 - 5.5e-06 26.1 0.2 1.5e-05 24.7 0.2 1.9 1 1 0 1 1 1 1 KH domain HLH PF00010.26 OWF38909.1 - 1.3e-12 47.4 0.1 3.1e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Foie-gras_1 PF11817.8 OWF38909.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 Exo_endo_phos PF03372.23 OWF38910.1 - 2.9e-10 40.1 0.0 1.1e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C2 PF00648.21 OWF38911.1 - 3.5e-13 49.2 0.4 6.6e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Calpain family cysteine protease Globin PF00042.22 OWF38911.1 - 5.6e-07 30.1 0.1 0.01 16.4 0.0 2.5 2 0 0 2 2 2 2 Globin IQ PF00612.27 OWF38911.1 - 0.021 14.6 0.1 0.059 13.2 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif MORN_2 PF07661.13 OWF38912.1 - 3.3e-06 26.7 5.0 37 5.0 0.0 6.7 4 2 5 9 9 9 1 MORN repeat variant SSXT PF05030.12 OWF38912.1 - 0.0011 18.6 2.5 9.3 6.0 0.0 4.4 1 1 1 2 2 2 2 SSXT protein (N-terminal region) SAM_DrpA PF18255.1 OWF38912.1 - 0.078 13.2 6.6 76 3.7 0.0 6.0 2 1 7 10 10 10 0 DNA processing protein A sterile alpha motif domain MmlI PF09448.10 OWF38912.1 - 7.4 7.1 18.3 1.4e+02 2.9 3.9 4.3 1 1 1 2 2 2 0 Methylmuconolactone methyl-isomerase MORN_2 PF07661.13 OWF38913.1 - 8.4e-05 22.4 6.3 48 4.7 0.1 6.6 4 3 6 10 10 10 0 MORN repeat variant SSXT PF05030.12 OWF38913.1 - 0.0014 18.2 2.4 2.8 7.7 0.2 4.0 1 1 2 3 3 3 2 SSXT protein (N-terminal region) SAM_DrpA PF18255.1 OWF38913.1 - 0.0033 17.6 3.8 1e+02 3.2 0.0 6.1 1 1 10 11 11 11 0 DNA processing protein A sterile alpha motif domain DUF370 PF04025.12 OWF38913.1 - 0.02 15.0 1.8 4.2 7.5 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF370) PLA1 PF02253.15 OWF38913.1 - 0.62 9.6 16.3 13 5.2 1.9 4.9 1 1 4 5 5 5 0 Phospholipase A1 CUE PF02845.16 OWF38913.1 - 2.5 7.9 7.3 20 5.0 0.2 4.7 3 2 2 6 6 6 0 CUE domain MukF_M PF17192.4 OWF38913.1 - 8.5 6.1 7.8 21 4.8 1.2 3.2 1 1 3 4 4 4 0 MukF middle domain CholecysA-Rec_N PF09193.10 OWF38914.1 - 4.3 7.4 26.6 51 4.0 1.3 7.4 1 1 7 8 8 8 0 Cholecystokinin A receptor, N-terminal RRM_1 PF00076.22 OWF38915.1 - 4.6e-46 154.5 1.9 1e-16 60.5 0.2 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 OWF38915.1 - 3.6e-24 84.5 0.4 1.5e-23 82.5 0.1 2.1 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 OWF38915.1 - 1.8e-06 27.9 0.1 0.36 11.0 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 OWF38915.1 - 0.0029 17.2 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 OWF38915.1 - 0.15 11.7 0.0 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 TAF8_C PF10406.9 OWF38915.1 - 0.46 11.1 0.1 0.46 11.1 0.1 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term RRM_1 PF00076.22 OWF38916.1 - 1.3e-41 140.3 2.8 1.6e-15 56.6 0.2 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 OWF38916.1 - 3.1e-23 81.5 0.1 6.1e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 OWF38916.1 - 4.3e-07 30.0 0.3 0.44 10.7 0.0 3.7 2 1 1 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 OWF38916.1 - 0.0085 15.7 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4473 PF14747.6 OWF38916.1 - 0.069 13.7 0.1 0.76 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) PHM7_cyt PF14703.6 OWF38916.1 - 1.5 9.1 4.4 2.2 8.5 0.3 2.8 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Cupin_8 PF13621.6 OWF38917.1 - 4.1e-33 115.2 2.2 9e-33 114.0 2.2 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OWF38917.1 - 0.00067 19.2 0.3 0.0012 18.4 0.3 1.8 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OWF38917.1 - 0.02 15.3 0.4 0.046 14.1 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase CUB PF00431.20 OWF38919.1 - 4e-84 278.2 1.6 1.8e-19 70.1 0.0 5.4 5 0 0 5 5 5 5 CUB domain Ldl_recept_a PF00057.18 OWF38919.1 - 0.0019 18.4 5.3 0.0055 16.9 5.3 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Pyocin_S PF06958.12 OWF38919.1 - 1.2 9.7 4.0 2.2 8.8 4.0 1.4 1 0 0 1 1 1 0 S-type Pyocin 5HT_transport_N PF03491.13 OWF38920.1 - 2.6 8.3 13.4 17 5.7 0.4 4.3 1 1 3 4 4 4 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus PH_18 PF18469.1 OWF38920.1 - 2.6 8.0 5.9 1.1e+02 2.8 0.1 5.1 1 1 2 5 5 5 0 Pleckstrin homology domain SPATA3 PF15662.5 OWF38921.1 - 0.0004 21.1 33.0 0.2 12.3 7.2 3.2 1 1 2 3 3 3 3 Spermatogenesis-associated protein 3 family CCDC117 PF15810.5 OWF38921.1 - 0.77 10.1 20.6 1.5 9.1 6.0 3.2 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 117 DUF1236 PF06823.12 OWF38921.1 - 6.7 6.7 40.3 8.5 6.3 1.4 7.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1236) Beta-lactamase PF00144.24 OWF38923.1 - 6.1e-45 153.9 0.0 1e-44 153.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase BTRD1 PF17660.1 OWF38923.1 - 0.027 14.3 0.3 25 4.8 0.0 3.4 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 DUF1891 PF09004.10 OWF38924.1 - 0.03 13.9 1.3 0.078 12.6 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) SPO22 PF08631.10 OWF38925.1 - 2e-60 204.6 13.6 9.4e-53 179.5 0.5 3.5 2 1 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 OWF38925.1 - 8.5e-12 45.2 18.8 1.7e-05 25.0 4.1 7.7 8 2 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF38925.1 - 0.00037 20.5 5.5 0.45 10.9 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF38925.1 - 0.00078 19.2 10.2 0.47 10.4 0.6 6.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF38925.1 - 0.0027 17.7 25.4 0.12 12.6 0.6 8.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF38925.1 - 1.8 9.3 6.4 15 6.3 2.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Ric8 PF10165.9 OWF38925.1 - 2.3 7.2 22.3 0.78 8.7 10.4 3.7 3 2 0 4 4 4 0 Guanine nucleotide exchange factor synembryn Forkhead PF00250.18 OWF38927.1 - 2.5e-25 88.5 0.2 5.9e-25 87.3 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain FOXO-TAD PF16676.5 OWF38927.1 - 2.5e-07 31.0 4.6 2.5e-07 31.0 4.6 1.8 2 0 0 2 2 2 1 Transactivation domain of FOXO protein family MFS_1 PF07690.16 OWF38928.1 - 1.2e-36 126.4 34.1 1.2e-36 126.4 34.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF38928.1 - 5.9e-06 25.4 21.5 4.3e-05 22.5 21.5 1.9 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 OWF38928.1 - 0.003 16.9 3.6 0.003 16.9 3.6 2.1 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Vma12 PF11712.8 OWF38928.1 - 0.065 13.3 1.2 0.13 12.3 1.2 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.16 OWF38929.1 - 3.1e-41 141.5 24.1 3.1e-41 141.5 24.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF38929.1 - 1e-06 28.3 2.8 1e-06 28.3 2.8 2.9 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OWF38929.1 - 1.1e-06 27.8 4.9 1.1e-06 27.8 4.9 2.5 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 OWF38929.1 - 8.8e-06 24.8 15.9 2.3e-05 23.5 15.9 1.6 1 1 0 1 1 1 1 MFS_1 like family WD40 PF00400.32 OWF38930.1 - 2.2e-20 72.6 15.9 0.0013 19.5 0.1 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 OWF38930.1 - 0.0013 18.7 0.1 0.0045 16.9 0.1 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OWF38930.1 - 0.019 13.6 3.2 0.88 8.1 0.0 3.3 1 1 2 4 4 4 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OWF38930.1 - 0.024 14.9 3.4 8.1 6.8 0.6 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HYR PF02494.16 OWF38931.1 - 2e-08 34.4 2.2 4.8e-07 30.0 0.1 2.9 2 1 0 2 2 2 1 HYR domain WAP PF00095.21 OWF38931.1 - 4.4e-07 30.2 6.1 4.4e-07 30.2 6.1 6.2 4 2 0 4 4 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' FAM176 PF14851.6 OWF38931.1 - 2.2e-06 27.4 3.0 0.00016 21.3 2.8 2.3 2 0 0 2 2 2 1 FAM176 family VWC PF00093.18 OWF38931.1 - 5.7e-06 26.6 14.0 5.7e-06 26.6 14.0 5.1 2 1 2 4 4 2 1 von Willebrand factor type C domain EGF PF00008.27 OWF38931.1 - 0.0086 16.4 8.3 0.0086 16.4 8.3 6.0 5 2 0 5 5 4 2 EGF-like domain EGF_2 PF07974.13 OWF38931.1 - 0.022 15.1 11.8 0.022 15.1 11.8 5.5 4 1 0 4 4 3 0 EGF-like domain hEGF PF12661.7 OWF38931.1 - 0.035 14.7 43.5 0.049 14.3 10.9 5.7 4 0 0 4 4 4 0 Human growth factor-like EGF TRAP_alpha PF03896.16 OWF38931.1 - 0.036 13.3 5.3 0.064 12.5 5.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 OWF38931.1 - 0.64 8.0 24.8 0.92 7.5 24.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OWF38931.1 - 1.5 6.9 16.7 2.2 6.4 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OWF38931.1 - 3 6.3 12.7 4.3 5.8 12.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 OWF38931.1 - 5.4 6.3 12.0 8.2 5.7 12.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Roughex PF06020.11 OWF38931.1 - 8.5 5.4 9.7 15 4.5 9.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Comm PF15957.5 OWF38932.1 - 0.0078 16.5 1.2 0.013 15.8 1.2 1.3 1 1 0 1 1 1 1 Commissureless MLANA PF14991.6 OWF38932.1 - 1.2 9.5 5.1 10 6.4 0.2 2.1 1 1 1 2 2 2 0 Protein melan-A HYR PF02494.16 OWF38933.1 - 3.2e-06 27.4 5.5 1.9e-05 24.9 0.0 3.2 3 1 0 3 3 3 2 HYR domain HlyD_D4 PF16572.5 OWF38935.1 - 0.045 13.6 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB BIV_Env PF05858.12 OWF38935.1 - 0.1 10.7 0.1 0.12 10.5 0.1 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) DUF2709 PF10915.8 OWF38936.1 - 0.098 11.9 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) Crystall_3 PF08964.10 OWF38937.1 - 0.00024 21.2 15.3 9.8 6.4 0.1 5.9 1 1 4 6 6 6 4 Beta/Gamma crystallin HCV_env PF01539.17 OWF38937.1 - 0.26 11.0 4.4 10 5.8 0.1 3.9 1 1 3 5 5 5 0 Hepatitis C virus envelope glycoprotein E1 Nsp2a_N PF17896.1 OWF38937.1 - 5.5 6.1 6.6 19 4.3 0.2 3.0 1 1 1 3 3 3 0 Replicase polyprotein 1a N-terminal domain I-set PF07679.16 OWF38939.1 - 4.9e-114 372.7 0.1 3.2e-14 52.8 0.0 11.4 11 0 0 11 11 10 10 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF38939.1 - 1.2e-113 371.8 13.6 2.1e-13 50.6 0.1 11.5 11 0 0 11 11 10 10 Immunoglobulin domain Ig_2 PF13895.6 OWF38939.1 - 1.3e-78 259.4 5.5 6.2e-10 39.3 0.1 10.6 10 0 0 10 10 10 10 Immunoglobulin domain fn3 PF00041.21 OWF38939.1 - 3.3e-69 229.3 16.6 2.9e-14 53.2 0.1 6.7 6 0 0 6 6 6 6 Fibronectin type III domain ig PF00047.25 OWF38939.1 - 8.8e-69 227.7 7.5 2.6e-08 33.9 0.0 11.1 10 1 0 10 10 10 9 Immunoglobulin domain V-set PF07686.17 OWF38939.1 - 2.9e-27 95.0 31.1 0.00019 21.6 0.0 15.7 12 6 1 13 13 12 7 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF38939.1 - 7.1e-22 77.3 0.1 0.004 17.2 0.0 9.2 9 0 0 9 9 9 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF38939.1 - 7.7e-14 51.9 0.0 0.66 10.4 0.0 8.1 8 0 0 8 8 8 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF38939.1 - 2.2e-12 46.3 0.2 0.17 11.5 0.0 7.5 8 0 0 8 8 8 3 Immunoglobulin domain C1-set PF07654.15 OWF38939.1 - 6.3e-10 39.3 1.4 0.86 10.0 0.0 7.5 7 0 0 7 7 7 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 OWF38939.1 - 4.4e-09 36.5 0.4 1.8 8.9 0.0 7.2 7 1 0 7 7 7 2 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 OWF38939.1 - 1.6e-06 28.6 11.0 0.16 12.6 0.1 6.0 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain V-set_CD47 PF08204.11 OWF38939.1 - 0.00043 20.3 0.0 3 7.8 0.0 5.4 6 1 0 6 6 6 1 CD47 immunoglobulin-like domain Interfer-bind PF09294.10 OWF38939.1 - 0.0012 19.1 1.0 0.86 9.9 0.0 4.0 4 0 0 4 4 3 1 Interferon-alpha/beta receptor, fibronectin type III Receptor_2B4 PF11465.8 OWF38939.1 - 0.014 15.6 0.1 5.1 7.3 0.0 4.2 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 Adeno_E3_CR1 PF02440.15 OWF38939.1 - 3.2 7.6 5.5 8.5 6.2 0.1 4.5 5 0 0 5 5 4 0 Adenovirus E3 region protein CR1 Mucin-like PF16058.5 OWF38940.1 - 0.014 15.4 5.7 0.058 13.5 0.2 2.4 1 1 1 2 2 2 0 Mucin-like Rhodopsin_N PF10413.9 OWF38940.1 - 0.046 13.5 2.3 27 4.7 0.0 4.7 3 2 2 5 5 5 0 Amino terminal of the G-protein receptor rhodopsin Cornifin PF02389.15 OWF38941.1 - 0.00059 20.0 137.7 0.24 11.6 15.6 8.7 1 1 5 7 7 7 5 Cornifin (SPRR) family NDK PF00334.19 OWF38942.1 - 4.1e-34 117.5 0.0 5.4e-19 68.5 0.0 5.3 5 0 0 5 5 5 3 Nucleoside diphosphate kinase Ank_2 PF12796.7 OWF38943.1 - 3.4e-29 101.2 0.5 7.3e-16 58.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF38943.1 - 1.2e-26 91.9 0.5 3.8e-06 27.1 0.1 6.2 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OWF38943.1 - 3.4e-24 84.9 0.2 2.4e-09 37.5 0.1 4.0 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF38943.1 - 2.5e-22 76.5 0.6 0.0007 19.9 0.1 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OWF38943.1 - 5.6e-17 61.6 0.7 1.1e-08 35.1 0.1 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 OWF38943.1 - 3.7e-12 46.5 0.4 8.8e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF38943.1 - 5.2e-09 36.1 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SF-assemblin PF06705.11 OWF38943.1 - 0.41 10.0 6.2 0.22 10.8 0.2 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin LMBR1 PF04791.16 OWF38943.1 - 5.5 5.8 4.3 7.9 5.3 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein G8 PF10162.9 OWF38944.1 - 9.2e-19 67.7 0.0 2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 OWF38944.1 - 0.00043 20.2 4.3 0.00044 20.1 0.8 2.8 2 1 1 3 3 3 1 Right handed beta helix region ILEI PF15711.5 OWF38944.1 - 0.024 15.1 0.2 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 Interleukin-like EMT inducer zf-C2H2_2 PF12756.7 OWF38945.1 - 0.15 12.4 0.0 0.15 12.4 0.0 8.3 5 3 3 8 8 8 0 C2H2 type zinc-finger (2 copies) Collagen PF01391.18 OWF38946.1 - 1.1e-21 76.3 87.8 5.9e-08 32.3 29.4 3.7 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) C1q PF00386.21 OWF38946.1 - 8.1e-18 64.9 0.1 1.2e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF38946.1 - 0.03 14.2 0.7 0.049 13.6 0.7 1.2 1 0 0 1 1 1 0 BclA C-terminal domain Tup_N PF08581.10 OWF38946.1 - 0.038 14.3 0.3 0.063 13.6 0.3 1.3 1 0 0 1 1 1 0 Tup N-terminal UPF0184 PF03670.13 OWF38946.1 - 0.18 12.2 0.2 0.41 11.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DEAD PF00270.29 OWF38947.1 - 1.3e-07 31.6 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OWF38947.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SNF PF00209.18 OWF38948.1 - 3.3e-193 643.1 36.1 2.2e-190 633.8 36.1 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Ig_2 PF13895.6 OWF38949.1 - 5e-16 58.8 20.6 4.3e-09 36.6 0.2 5.5 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.6 OWF38949.1 - 2.8e-14 53.5 25.8 8.8e-08 32.6 0.7 6.7 6 1 0 6 6 6 3 Immunoglobulin domain I-set PF07679.16 OWF38949.1 - 4.1e-10 39.6 8.8 0.019 15.0 0.6 6.5 6 1 0 6 6 6 3 Immunoglobulin I-set domain V-set PF07686.17 OWF38949.1 - 1.4e-06 28.5 10.2 0.58 10.4 0.0 6.3 5 1 1 6 6 6 2 Immunoglobulin V-set domain C1-set PF07654.15 OWF38949.1 - 0.024 15.0 5.3 0.19 12.1 0.6 3.7 3 1 0 3 3 3 0 Immunoglobulin C1-set domain C2-set_2 PF08205.12 OWF38949.1 - 0.31 11.1 8.4 0.29 11.2 1.0 3.8 3 1 0 3 3 3 0 CD80-like C2-set immunoglobulin domain ig PF00047.25 OWF38949.1 - 3.8 7.7 18.9 4 7.7 0.3 5.8 6 2 1 7 7 7 0 Immunoglobulin domain PARP PF00644.20 OWF38950.1 - 2.4e-51 174.1 0.0 4e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OWF38950.1 - 1.1e-43 148.6 0.5 1.8e-43 147.9 0.5 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OWF38950.1 - 1.7e-25 88.8 1.4 5.3e-25 87.3 1.4 1.9 1 0 0 1 1 1 1 WGR domain Fer2_4 PF13510.6 OWF38950.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SNF PF00209.18 OWF38951.1 - 2.6e-202 673.2 34.7 4.1e-202 672.5 34.7 1.3 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family OstA PF03968.14 OWF38951.1 - 0.0019 18.4 1.2 0.0033 17.6 1.2 1.3 1 0 0 1 1 1 1 OstA-like protein Glycos_transf_4 PF00953.21 OWF38952.1 - 6.2e-37 127.0 15.9 6.2e-37 127.0 15.9 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 Histone_H2A_C PF16211.5 OWF38953.1 - 1.3e-20 72.8 1.4 1.3e-20 72.8 1.4 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 OWF38953.1 - 4.3e-16 59.5 0.0 5.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OWF38953.1 - 1.2e-05 25.5 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 OWF38954.1 - 1.5e-68 231.1 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38954.1 - 9.8e-34 116.8 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF38954.1 - 0.0074 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OWF38954.1 - 0.016 15.1 0.1 0.04 13.8 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OWF38954.1 - 0.028 13.8 0.0 0.091 12.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sortilin-Vps10 PF15902.5 OWF38955.1 - 1.8e-104 350.0 1.0 2.7e-104 349.5 1.0 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Ldl_recept_a PF00057.18 OWF38955.1 - 2.2e-84 277.4 185.7 7.2e-11 42.1 9.8 11.4 11 0 0 11 11 11 10 Low-density lipoprotein receptor domain class A fn3 PF00041.21 OWF38955.1 - 5.9e-42 141.9 14.1 1.1e-09 38.4 0.2 6.7 6 0 0 6 6 6 6 Fibronectin type III domain Sortilin_C PF15901.5 OWF38955.1 - 2.3e-35 122.4 0.2 2.3e-35 122.4 0.2 5.4 4 1 2 6 6 6 1 Sortilin, neurotensin receptor 3, C-terminal Ldl_recept_b PF00058.17 OWF38955.1 - 2.6e-29 101.4 11.3 4.5e-07 30.2 1.7 5.9 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B Pur_ac_phosph_N PF16656.5 OWF38955.1 - 9.4e-06 26.1 14.2 0.071 13.7 1.3 5.9 4 1 1 5 5 5 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF38955.1 - 0.00046 20.5 0.5 0.16 12.3 0.0 3.7 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III SGL PF08450.12 OWF38955.1 - 0.0034 17.0 0.9 0.58 9.7 0.1 3.7 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region BNR PF02012.20 OWF38955.1 - 0.047 13.7 14.0 6.7 7.1 0.0 6.5 6 0 0 6 6 6 0 BNR/Asp-box repeat YDG PF18657.1 OWF38955.1 - 0.088 13.0 0.2 6.7 7.0 0.0 3.4 3 0 0 3 3 3 0 YDG domain Baculo_PEP_C PF04513.12 OWF38956.1 - 3.5e-05 23.9 7.0 0.00012 22.1 7.0 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 OWF38956.1 - 0.23 11.9 22.6 5.6 7.4 11.5 3.0 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Col_cuticle_N PF01484.17 OWF38956.1 - 0.47 10.5 12.7 8.1 6.6 0.5 4.2 1 1 3 4 4 4 0 Nematode cuticle collagen N-terminal domain Holin_SPP1 PF04688.13 OWF38956.1 - 3.4 7.9 28.8 1.6 9.0 4.1 3.7 1 1 2 3 3 3 0 SPP1 phage holin RGS-like PF09128.11 OWF38957.1 - 1.3e-39 135.8 1.1 3.8e-39 134.4 0.0 2.5 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain PH_16 PF17838.1 OWF38957.1 - 4.1e-34 117.1 1.2 9e-34 116.0 1.2 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 OWF38957.1 - 1.5e-30 106.8 10.8 2.9e-30 105.8 8.1 2.7 2 0 0 2 2 2 1 RhoGEF domain PDZ PF00595.24 OWF38957.1 - 1.6e-11 44.3 0.2 4.2e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF38957.1 - 3.4e-10 39.6 0.1 9.9e-10 38.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.22 OWF38957.1 - 6.1e-10 38.8 6.8 1.2e-09 37.9 6.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_13 PF16652.5 OWF38957.1 - 1.3e-07 31.6 1.4 3.6e-07 30.1 1.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ_2 PF13180.6 OWF38957.1 - 2e-06 28.1 2.2 2.5e-06 27.7 0.1 2.4 2 0 0 2 2 1 1 PDZ domain RGS PF00615.19 OWF38957.1 - 8.6e-06 26.0 0.0 8.6e-06 26.0 0.0 3.4 4 0 0 4 4 4 1 Regulator of G protein signaling domain Tricorn_PDZ PF14685.6 OWF38957.1 - 0.099 12.6 0.2 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain PH PF00169.29 OWF38957.1 - 0.12 12.8 1.8 0.33 11.5 0.1 2.8 3 0 0 3 3 2 0 PH domain DUF2318 PF10080.9 OWF38957.1 - 0.23 11.6 2.6 0.56 10.4 2.6 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_2 PF03107.16 OWF38957.1 - 0.24 11.7 3.1 0.58 10.5 3.1 1.7 1 0 0 1 1 1 0 C1 domain Zn_Tnp_IS91 PF14319.6 OWF38957.1 - 0.24 11.4 4.9 0.78 9.8 4.9 1.9 1 0 0 1 1 1 0 Transposase zinc-binding domain Zf_RING PF16744.5 OWF38957.1 - 0.9 9.7 4.1 2.4 8.3 4.1 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 OWF38957.1 - 1.4 9.3 5.7 2.9 8.3 5.7 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OWF38957.1 - 1.9 8.2 4.1 3.8 7.2 4.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SET PF00856.28 OWF38958.1 - 1.8e-05 25.2 0.4 2.5e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 SET domain zf_PR_Knuckle PF18445.1 OWF38958.1 - 6.4e-05 22.7 0.2 0.00013 21.6 0.2 1.5 1 0 0 1 1 1 1 PR zinc knuckle motif PIG-X PF08320.12 OWF38958.1 - 0.13 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 PIG-X / PBN1 BLOC1_2 PF10046.9 OWF38959.1 - 3.8e-19 68.8 28.3 0.001 19.3 0.2 8.3 1 1 7 8 8 8 6 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 OWF38959.1 - 2.9e-15 56.4 18.6 0.00057 19.9 0.3 5.2 1 1 3 4 4 4 4 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OWF38959.1 - 3.6e-12 46.5 21.1 0.00014 21.9 0.9 3.5 1 1 2 3 3 3 3 Laminin Domain II Nsp1_C PF05064.13 OWF38959.1 - 1.3e-11 44.3 8.0 0.00012 21.8 0.2 4.0 1 1 2 3 3 3 2 Nsp1-like C-terminal region DUF16 PF01519.16 OWF38959.1 - 1.6e-11 44.6 28.9 0.14 12.6 8.9 6.2 1 1 2 3 3 3 2 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 OWF38959.1 - 2.3e-11 43.5 20.3 0.025 14.6 0.1 6.7 1 1 7 8 8 8 5 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 OWF38959.1 - 6.6e-11 42.7 5.5 0.46 11.1 0.0 7.6 2 1 4 7 7 6 1 SlyX Baculo_PEP_C PF04513.12 OWF38959.1 - 7.7e-11 42.2 5.1 0.014 15.4 0.2 4.1 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 OWF38959.1 - 2.3e-10 40.8 20.4 0.001 19.2 1.2 3.9 1 1 2 3 3 3 3 Tropomyosin like AAA_13 PF13166.6 OWF38959.1 - 3.8e-09 35.8 13.6 1.5e-06 27.2 2.4 2.6 1 1 1 2 2 2 2 AAA domain XhlA PF10779.9 OWF38959.1 - 3.9e-09 36.6 24.9 0.051 13.8 0.3 7.4 3 2 2 7 7 7 3 Haemolysin XhlA Spc7 PF08317.11 OWF38959.1 - 5.1e-09 35.4 14.7 3.8e-05 22.7 0.9 3.4 1 1 2 3 3 3 2 Spc7 kinetochore protein FlaC_arch PF05377.11 OWF38959.1 - 1.3e-08 35.1 41.8 0.14 12.5 0.6 8.2 2 2 7 9 9 9 5 Flagella accessory protein C (FlaC) CLZ PF16526.5 OWF38959.1 - 2.2e-08 34.3 23.1 0.17 12.3 2.5 8.1 1 1 8 9 9 8 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 OWF38959.1 - 4.6e-08 33.3 1.4 0.16 12.1 0.0 3.9 1 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 OWF38959.1 - 1.4e-07 31.8 17.8 0.02 15.1 1.4 4.2 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family RPW8 PF05659.11 OWF38959.1 - 2.2e-07 30.6 25.2 0.012 15.3 3.2 6.0 1 1 5 6 6 6 3 Arabidopsis broad-spectrum mildew resistance protein RPW8 DASH_Dam1 PF08653.10 OWF38959.1 - 6.7e-07 29.0 5.3 32 4.4 0.0 8.5 5 3 5 11 11 9 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 OWF38959.1 - 2.1e-06 28.1 32.6 0.31 11.5 4.5 6.2 1 1 3 5 5 5 3 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 OWF38959.1 - 2.4e-06 26.1 20.3 6e-06 24.7 10.8 2.3 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA KASH_CCD PF14662.6 OWF38959.1 - 4.1e-06 26.8 21.3 0.0065 16.3 6.4 3.8 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 or KASH TelA PF05816.11 OWF38959.1 - 4.2e-06 26.1 9.5 0.003 16.7 1.5 2.9 1 1 2 3 3 3 2 Toxic anion resistance protein (TelA) Apolipoprotein PF01442.18 OWF38959.1 - 4.4e-06 26.7 6.7 6.6e-06 26.1 0.9 3.0 1 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Snapin_Pallidin PF14712.6 OWF38959.1 - 4.5e-06 27.0 22.5 0.065 13.7 3.2 6.2 1 1 6 7 7 7 2 Snapin/Pallidin bZIP_1 PF00170.21 OWF38959.1 - 5.8e-06 26.3 24.1 0.22 11.6 0.2 7.8 3 2 5 9 9 9 1 bZIP transcription factor HemX PF04375.14 OWF38959.1 - 7.6e-06 25.4 0.7 0.032 13.5 0.0 3.6 2 1 2 4 4 3 1 HemX, putative uroporphyrinogen-III C-methyltransferase Vps51 PF08700.11 OWF38959.1 - 8.3e-06 25.8 12.6 15 5.8 0.2 7.9 3 2 3 7 7 7 0 Vps51/Vps67 ZapB PF06005.12 OWF38959.1 - 8.7e-06 26.1 19.5 0.14 12.6 0.5 6.4 1 1 5 6 6 6 2 Cell division protein ZapB DUF4795 PF16043.5 OWF38959.1 - 1.2e-05 25.1 22.1 0.00079 19.1 10.7 4.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4795) CENP-F_leu_zip PF10473.9 OWF38959.1 - 1.6e-05 25.0 24.6 0.028 14.4 4.0 4.7 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2959 PF11172.8 OWF38959.1 - 1.9e-05 24.9 7.0 0.002 18.3 0.1 3.1 1 1 0 2 2 2 1 Protein of unknown function (DUF2959) ERM PF00769.19 OWF38959.1 - 2.3e-05 24.3 2.0 0.00031 20.7 0.4 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family HrpB7 PF09486.10 OWF38959.1 - 2.6e-05 24.6 0.0 2.2 8.7 0.0 4.3 2 1 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) PspA_IM30 PF04012.12 OWF38959.1 - 2.9e-05 23.8 11.7 0.46 10.0 1.8 4.9 1 1 3 4 4 4 2 PspA/IM30 family CEP209_CC5 PF16574.5 OWF38959.1 - 2.9e-05 24.2 14.8 0.0003 21.0 2.9 3.3 1 1 2 3 3 3 1 Coiled-coil region of centrosome protein CE290 ATG16 PF08614.11 OWF38959.1 - 4.8e-05 23.7 6.8 0.21 11.8 0.3 3.7 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 OWF38959.1 - 5e-05 22.8 16.0 0.00018 21.0 13.5 2.4 1 1 2 3 3 3 2 Tropomyosin TolA_bind_tri PF16331.5 OWF38959.1 - 5.2e-05 23.2 0.2 0.61 10.2 0.0 4.4 3 2 1 4 4 4 1 TolA binding protein trimerisation QWRF PF04484.12 OWF38959.1 - 5.4e-05 23.1 4.5 6.4 6.4 0.0 5.2 2 1 3 5 5 5 0 QWRF family BRCA-2_OB3 PF09104.10 OWF38959.1 - 7.2e-05 22.5 0.5 1.2 8.8 0.1 4.6 3 2 2 5 5 5 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 TRAF_BIRC3_bd PF16673.5 OWF38959.1 - 8.3e-05 22.3 13.6 0.017 14.9 0.2 6.3 2 2 4 6 6 5 2 TNF receptor-associated factor BIRC3 binding domain APG17 PF04108.12 OWF38959.1 - 0.00011 21.5 12.3 0.0015 17.7 0.6 3.6 1 1 2 3 3 3 1 Autophagy protein Apg17 COG5 PF10392.9 OWF38959.1 - 0.00018 21.7 11.5 0.12 12.6 0.3 5.2 1 1 3 5 5 5 1 Golgi transport complex subunit 5 DUF4200 PF13863.6 OWF38959.1 - 0.00024 21.5 9.8 0.79 10.1 1.4 4.8 1 1 3 4 4 4 1 Domain of unknown function (DUF4200) Vps53_N PF04100.12 OWF38959.1 - 0.00026 20.1 17.3 0.025 13.5 0.8 3.8 1 1 1 3 3 3 2 Vps53-like, N-terminal YscO PF07321.12 OWF38959.1 - 0.00036 20.5 6.9 0.024 14.6 0.3 4.1 2 2 3 5 5 5 1 Type III secretion protein YscO Fez1 PF06818.15 OWF38959.1 - 0.00036 21.1 12.9 0.95 9.9 0.2 3.3 1 1 2 3 3 3 1 Fez1 BRE1 PF08647.11 OWF38959.1 - 0.00044 20.3 15.7 1.3 9.2 0.5 4.6 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 OWF38959.1 - 0.00044 20.1 14.4 0.066 13.0 1.8 3.8 1 1 3 4 4 4 2 Protein of unknown function (DUF724) Laminin_I PF06008.14 OWF38959.1 - 0.00049 19.9 11.9 0.093 12.4 0.5 3.6 1 1 1 3 3 3 1 Laminin Domain I Serine_rich PF08824.10 OWF38959.1 - 0.00051 20.1 1.5 1.5 8.8 0.0 3.7 1 1 2 3 3 3 0 Serine rich protein interaction domain Lebercilin PF15619.6 OWF38959.1 - 0.00056 19.6 14.2 0.13 11.9 1.6 3.8 1 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 OWF38959.1 - 0.00059 18.9 19.6 0.029 13.3 4.0 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF812) Dynactin_p22 PF07426.11 OWF38959.1 - 0.00061 19.7 21.8 0.011 15.6 7.6 5.0 1 1 2 3 3 3 1 Dynactin subunit p22 HOOK PF05622.12 OWF38959.1 - 0.00078 17.7 22.0 0.0028 15.9 8.2 2.6 1 1 1 2 2 2 1 HOOK protein TMPIT PF07851.13 OWF38959.1 - 0.0008 18.8 7.7 0.77 8.9 1.0 3.4 1 1 2 3 3 3 1 TMPIT-like protein DUF3450 PF11932.8 OWF38959.1 - 0.00081 18.8 6.6 0.18 11.1 0.2 3.6 1 1 3 4 4 4 2 Protein of unknown function (DUF3450) FPP PF05911.11 OWF38959.1 - 0.00085 17.7 12.2 0.057 11.6 3.7 2.6 1 1 2 3 3 3 2 Filament-like plant protein, long coiled-coil Jnk-SapK_ap_N PF09744.9 OWF38959.1 - 0.0011 19.3 12.3 0.047 13.9 2.2 4.2 1 1 2 3 3 3 1 JNK_SAPK-associated protein-1 TACC_C PF05010.14 OWF38959.1 - 0.0012 18.7 18.5 0.16 11.7 1.8 4.4 1 1 3 4 4 4 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LPP PF04728.13 OWF38959.1 - 0.0017 18.7 19.8 9.9 6.6 0.1 7.7 5 4 4 10 10 9 0 Lipoprotein leucine-zipper DUF4686 PF15742.5 OWF38959.1 - 0.0017 17.5 12.4 0.0091 15.2 2.9 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4686) ISG65-75 PF11727.8 OWF38959.1 - 0.0019 17.5 9.8 0.35 10.1 0.8 3.2 2 1 0 3 3 3 1 Invariant surface glycoprotein DUF713 PF05218.14 OWF38959.1 - 0.0019 17.9 5.8 0.57 9.9 0.4 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF713) FH2 PF02181.23 OWF38959.1 - 0.002 17.4 13.6 0.21 10.7 0.8 3.5 2 1 2 4 4 4 2 Formin Homology 2 Domain KxDL PF10241.9 OWF38959.1 - 0.002 18.4 5.1 1.5 9.2 0.7 3.7 3 1 1 4 4 2 0 Uncharacterized conserved protein Myosin_tail_1 PF01576.19 OWF38959.1 - 0.0024 15.8 26.1 0.013 13.4 12.4 2.1 1 1 1 2 2 2 1 Myosin tail PTRF_SDPR PF15237.6 OWF38959.1 - 0.0025 17.5 23.1 0.11 12.0 4.2 3.6 1 1 1 3 3 3 1 PTRF/SDPR family DUF4407 PF14362.6 OWF38959.1 - 0.0026 17.2 0.8 0.72 9.2 0.1 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Prominin PF05478.11 OWF38959.1 - 0.0027 15.7 15.0 1.6 6.6 0.2 4.2 1 1 2 3 3 3 0 Prominin DUF2730 PF10805.8 OWF38959.1 - 0.003 17.6 27.2 0.77 9.9 1.8 5.4 1 1 3 5 5 4 1 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.8 OWF38959.1 - 0.0031 17.7 14.4 0.83 9.9 0.3 4.1 1 1 4 5 5 5 1 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 OWF38959.1 - 0.0037 17.5 27.8 0.64 10.3 2.3 5.8 1 1 5 6 6 6 1 Bacterial protein of unknown function (DUF948) DUF4988 PF16378.5 OWF38959.1 - 0.004 16.8 20.3 1.6 8.3 0.1 6.7 2 2 2 5 5 5 0 Domain of unknown function PI3K_P85_iSH2 PF16454.5 OWF38959.1 - 0.0047 16.5 11.9 0.91 9.1 0.5 4.9 1 1 2 3 3 3 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Trimer_CC PF08954.11 OWF38959.1 - 0.0049 16.4 17.5 12 5.5 0.1 7.8 5 3 3 8 8 6 0 Trimerisation motif Uso1_p115_C PF04871.13 OWF38959.1 - 0.0052 17.1 11.6 0.32 11.4 3.5 3.8 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 OWF38959.1 - 0.0053 16.9 14.4 0.044 13.9 2.5 3.4 1 1 3 4 4 3 2 Uncharacterised protein family (UPF0242) N-terminus DUF3829 PF12889.7 OWF38959.1 - 0.0055 16.2 18.2 2.6 7.4 0.2 5.1 1 1 2 4 4 4 0 Protein of unknown function (DUF3829) HAUS-augmin3 PF14932.6 OWF38959.1 - 0.0062 16.1 6.1 2.6 7.5 0.4 3.9 1 1 3 4 4 4 0 HAUS augmin-like complex subunit 3 SHE3 PF17078.5 OWF38959.1 - 0.0063 16.3 2.4 0.0063 16.3 2.4 3.4 1 1 2 3 3 3 1 SWI5-dependent HO expression protein 3 DUF489 PF04356.12 OWF38959.1 - 0.0065 16.5 2.9 9 6.3 0.1 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF489) Uds1 PF15456.6 OWF38959.1 - 0.008 16.3 6.1 1.1 9.4 1.2 4.0 2 1 1 3 3 3 1 Up-regulated During Septation Tektin PF03148.14 OWF38959.1 - 0.0081 15.0 12.4 0.22 10.2 1.4 4.6 1 1 5 7 7 7 1 Tektin family Vps5 PF09325.10 OWF38959.1 - 0.0083 15.7 7.2 2.2 7.7 0.2 3.9 2 1 0 3 3 3 0 Vps5 C terminal like Lectin_N PF03954.14 OWF38959.1 - 0.0095 15.7 10.1 0.11 12.3 3.2 4.6 1 1 0 2 2 2 1 Hepatic lectin, N-terminal domain CEP63 PF17045.5 OWF38959.1 - 0.01 15.7 11.3 0.68 9.8 7.8 3.5 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF4763 PF15960.5 OWF38959.1 - 0.011 15.1 8.1 2.1 7.6 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) DUF4446 PF14584.6 OWF38959.1 - 0.011 15.7 14.7 0.54 10.2 0.9 4.9 1 1 3 5 5 5 0 Protein of unknown function (DUF4446) TssO PF17561.2 OWF38959.1 - 0.011 15.8 20.7 0.85 9.7 0.2 6.8 3 2 4 7 7 7 0 Type VI secretion system, TssO DivIC PF04977.15 OWF38959.1 - 0.011 15.5 20.1 6.2 6.7 0.1 7.6 2 2 5 8 8 8 0 Septum formation initiator Syntaxin-6_N PF09177.11 OWF38959.1 - 0.012 16.2 17.3 1.5e+02 3.0 8.4 5.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal MAD PF05557.13 OWF38959.1 - 0.012 14.1 13.7 0.11 10.8 12.7 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein Spectrin PF00435.21 OWF38959.1 - 0.017 15.6 10.8 2.3 8.8 1.7 4.9 1 1 4 5 5 4 0 Spectrin repeat DUF5082 PF16888.5 OWF38959.1 - 0.018 15.3 13.1 13 6.1 0.9 6.0 1 1 4 5 5 5 0 Domain of unknown function (DUF5082) CALCOCO1 PF07888.11 OWF38959.1 - 0.02 13.7 12.4 0.23 10.3 4.4 2.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mod_r PF07200.13 OWF38959.1 - 0.021 14.9 11.2 0.74 9.9 0.6 4.3 1 1 4 5 5 5 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad4 PF08650.10 OWF38959.1 - 0.022 14.7 12.6 64 3.6 0.3 7.3 3 3 2 6 6 6 0 DASH complex subunit Dad4 SKA1 PF07160.12 OWF38959.1 - 0.023 14.5 18.6 0.57 10.0 3.1 4.9 1 1 3 4 4 4 0 Spindle and kinetochore-associated protein 1 Surfac_D-trimer PF09006.11 OWF38959.1 - 0.025 14.5 0.0 3 7.8 0.0 4.1 4 0 0 4 4 2 0 Lung surfactant protein D coiled-coil trimerisation MCPsignal PF00015.21 OWF38959.1 - 0.027 14.3 5.0 1.6 8.5 0.4 3.6 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FemAB PF02388.16 OWF38959.1 - 0.032 13.1 5.9 3.3 6.5 0.3 3.1 1 1 1 3 3 3 0 FemAB family CK2S PF15011.6 OWF38959.1 - 0.035 14.0 7.2 11 5.9 0.1 5.3 1 1 5 6 6 6 0 Casein Kinase 2 substrate Fzo_mitofusin PF04799.13 OWF38959.1 - 0.035 13.6 14.0 5.1 6.6 1.5 5.0 2 2 2 4 4 4 0 fzo-like conserved region Filament PF00038.21 OWF38959.1 - 0.042 13.4 15.7 1.8 8.1 15.8 2.9 1 1 0 1 1 1 0 Intermediate filament protein HSBP1 PF06825.12 OWF38959.1 - 0.046 13.6 7.8 2.3 8.1 0.1 5.6 5 2 0 5 5 4 0 Heat shock factor binding protein 1 CorA PF01544.18 OWF38959.1 - 0.049 13.0 13.9 1.4 8.2 0.0 4.5 1 1 4 5 5 4 0 CorA-like Mg2+ transporter protein Sec34 PF04136.15 OWF38959.1 - 0.06 13.2 2.9 1.4 8.8 0.1 3.4 1 1 2 4 4 4 0 Sec34-like family BST2 PF16716.5 OWF38959.1 - 0.063 13.9 11.9 3 8.5 0.1 5.3 1 1 4 6 6 6 0 Bone marrow stromal antigen 2 Taxilin PF09728.9 OWF38959.1 - 0.079 12.1 15.7 4.7 6.3 11.3 4.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein BAG PF02179.16 OWF38959.1 - 0.084 13.3 21.7 6.3 7.3 2.5 5.4 1 1 2 3 3 3 0 BAG domain Prefoldin PF02996.17 OWF38959.1 - 0.087 12.7 17.3 2 8.4 0.4 6.1 2 1 1 5 5 5 0 Prefoldin subunit Atg14 PF10186.9 OWF38959.1 - 0.088 11.9 4.1 0.77 8.8 0.1 2.7 1 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 YkyA PF10368.9 OWF38959.1 - 0.092 12.4 17.9 0.73 9.5 4.4 3.7 1 1 2 3 3 3 0 Putative cell-wall binding lipoprotein DUF211 PF02680.14 OWF38959.1 - 0.1 12.8 19.4 2.1 8.6 0.4 4.6 1 1 4 5 5 5 0 Uncharacterized ArCR, COG1888 APG6_N PF17675.1 OWF38959.1 - 0.11 13.0 11.0 2 8.9 2.6 3.9 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF745 PF05335.13 OWF38959.1 - 0.16 11.7 0.2 0.89 9.2 0.0 2.3 2 1 0 2 2 1 0 Protein of unknown function (DUF745) HsbA PF12296.8 OWF38959.1 - 0.17 12.3 4.7 18 5.8 0.0 4.5 1 1 2 4 4 4 0 Hydrophobic surface binding protein A DUF3782 PF12644.7 OWF38959.1 - 0.17 12.0 4.5 48 4.2 0.0 5.1 4 2 2 6 6 3 0 Protein of unknown function (DUF3782) DUF2203 PF09969.9 OWF38959.1 - 0.18 12.6 11.9 5.2 7.8 2.5 4.2 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF4472 PF14739.6 OWF38959.1 - 0.22 12.3 13.9 3.4 8.4 1.1 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) UPF0449 PF15136.6 OWF38959.1 - 0.23 11.9 9.0 3.7 8.1 0.9 4.3 1 1 2 4 4 2 0 Uncharacterised protein family UPF0449 ABC_tran_CTD PF16326.5 OWF38959.1 - 0.24 11.7 17.0 13 6.2 2.4 6.2 2 2 5 7 7 7 0 ABC transporter C-terminal domain FliD_C PF07195.12 OWF38959.1 - 0.32 10.4 7.1 3.6 6.9 0.0 4.0 2 2 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF641 PF04859.12 OWF38959.1 - 0.34 11.2 14.8 7.6 6.9 0.5 4.5 1 1 3 5 5 5 0 Plant protein of unknown function (DUF641) GCN5L1 PF06320.13 OWF38959.1 - 0.38 10.9 6.0 14 5.9 0.1 4.3 1 1 3 5 5 4 0 GCN5-like protein 1 (GCN5L1) Ax_dynein_light PF10211.9 OWF38959.1 - 0.42 10.5 16.0 4 7.4 0.5 5.3 1 1 4 5 5 5 0 Axonemal dynein light chain Spc29 PF17082.5 OWF38959.1 - 0.42 10.4 12.2 2.4 7.9 0.1 4.6 1 1 3 5 5 5 0 Spindle Pole Component 29 YabA PF06156.13 OWF38959.1 - 0.47 11.1 17.0 17 6.1 1.2 5.0 1 1 2 3 3 2 0 Initiation control protein YabA DUF4201 PF13870.6 OWF38959.1 - 0.53 10.0 17.4 3.3 7.4 4.2 4.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) Desmo_N PF06771.11 OWF38959.1 - 0.58 10.5 7.3 6.1 7.3 0.2 4.3 1 1 3 5 5 3 0 Viral Desmoplakin N-terminus Noelin-1 PF12308.8 OWF38959.1 - 0.81 9.7 11.4 2.8 8.0 0.1 4.4 1 1 2 5 5 4 0 Neurogenesis glycoprotein EMP24_GP25L PF01105.24 OWF38959.1 - 0.88 9.5 13.6 3.2 7.7 0.6 5.2 2 1 3 5 5 5 0 emp24/gp25L/p24 family/GOLD TRPM_tetra PF16519.5 OWF38959.1 - 0.96 9.6 10.5 7.2 6.8 0.3 5.3 4 2 1 5 5 3 0 Tetramerisation domain of TRPM COG2 PF06148.11 OWF38959.1 - 1 9.4 18.4 3.3 7.8 1.2 4.5 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LidA_Long_CC PF18641.1 OWF38959.1 - 1.1 9.3 6.7 0.34 11.0 0.5 3.0 2 1 1 3 3 2 0 LidA long coiled-coil domain Wtap PF17098.5 OWF38959.1 - 1.3 8.9 14.7 14 5.5 0.2 5.3 2 2 3 6 6 6 0 WTAP/Mum2p family Rootletin PF15035.6 OWF38959.1 - 1.5 8.8 8.5 1.2e+03 -0.6 8.5 3.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4298 PF14131.6 OWF38959.1 - 2.2 8.3 9.2 52 3.9 0.2 5.5 2 2 4 7 7 4 0 Domain of unknown function (DUF4298) DUF2205 PF10224.9 OWF38959.1 - 2.3 8.3 16.4 3.1 7.8 0.3 5.3 2 2 5 7 7 4 0 Short coiled-coil protein Spindle_Spc25 PF08234.12 OWF38959.1 - 2.6 8.3 14.8 3.6 7.9 0.4 5.4 1 1 3 5 5 4 0 Chromosome segregation protein Spc25 Csm1_N PF18504.1 OWF38959.1 - 3 8.2 26.5 5.5 7.4 1.0 6.9 2 2 5 8 8 7 0 Csm1 N-terminal domain CHDCT2 PF08074.11 OWF38959.1 - 3.7 7.7 8.2 3.4 7.8 0.8 3.5 1 1 1 3 3 3 0 CHDCT2 (NUC038) domain Bacillus_HBL PF05791.11 OWF38959.1 - 4.3 7.1 12.2 31 4.3 0.1 3.9 2 2 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) P4Ha_N PF08336.11 OWF38959.1 - 5 7.1 10.5 13 5.8 0.2 4.7 1 1 3 6 6 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HCR PF07111.12 OWF38959.1 - 5.1 5.0 9.9 2 6.4 3.4 2.8 1 1 1 2 2 2 0 Alpha helical coiled-coil rod protein (HCR) DUF4094 PF13334.6 OWF38959.1 - 6.8 7.2 14.9 2.3e+02 2.3 1.6 6.4 1 1 1 2 2 1 0 Domain of unknown function (DUF4094) Prefoldin_2 PF01920.20 OWF38959.1 - 7.3 6.6 27.5 0.15 12.0 1.9 6.2 1 1 4 5 5 5 0 Prefoldin subunit Osmo_CC PF08946.10 OWF38959.1 - 7.3 6.9 21.4 5.9 7.2 0.8 7.5 4 2 2 7 7 5 0 Osmosensory transporter coiled coil KLRAQ PF10205.9 OWF38959.1 - 8 6.8 17.7 27 5.1 1.8 4.2 2 1 3 5 5 5 0 Predicted coiled-coil domain-containing protein SPOUT_MTase_2 PF14419.6 OWF38959.1 - 8.7 5.7 10.8 5.6 6.3 0.5 3.4 1 1 1 3 3 3 0 AF2226-like SPOUT RNA Methylase fused to THUMP EF-hand_7 PF13499.6 OWF38960.1 - 3.1e-14 53.2 7.6 5.2e-08 33.2 0.4 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF38960.1 - 2.3e-12 45.8 9.8 7.2e-08 31.8 0.9 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OWF38960.1 - 4.6e-12 44.6 12.1 1.2e-07 30.8 1.6 4.6 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 OWF38960.1 - 4e-07 29.8 10.2 0.0062 16.4 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF38960.1 - 2.1e-06 26.9 3.7 1.6e-05 24.1 1.5 2.7 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 OWF38960.1 - 0.00011 22.1 0.0 0.63 10.1 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Syntaxin PF00804.25 OWF38960.1 - 0.0031 17.2 0.4 0.35 10.5 0.1 2.1 2 0 0 2 2 2 1 Syntaxin EF-hand_9 PF14658.6 OWF38960.1 - 0.0038 17.5 0.0 3.9 7.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 OWF38960.1 - 0.014 15.2 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain GPHH PF16905.5 OWF38960.1 - 0.025 14.3 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SPARC_Ca_bdg PF10591.9 OWF38960.1 - 0.037 14.3 0.6 0.09 13.1 0.2 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF38960.1 - 0.12 13.3 0.3 0.75 10.7 0.1 2.0 1 1 1 2 2 2 0 EF-hand domain Med23 PF11573.8 OWF38961.1 - 0 1843.1 18.0 0 1842.9 18.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Pkinase PF00069.25 OWF38962.1 - 4.3e-69 232.8 0.2 6.1e-69 232.3 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38962.1 - 1.5e-47 162.1 0.5 2.7e-47 161.2 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1 PF00415.18 OWF38962.1 - 2.5e-44 149.7 22.5 4.8e-10 39.9 0.1 8.4 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF38962.1 - 1.6e-19 69.2 31.9 2.6e-06 27.1 0.7 7.9 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 OWF38962.1 - 1.9e-07 30.7 0.1 2.8e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF38962.1 - 0.00034 19.7 0.8 0.00067 18.7 0.8 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF38962.1 - 0.001 19.1 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF38962.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OWF38962.1 - 0.032 13.6 0.2 0.051 12.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-oxoacid_dh PF00198.23 OWF38963.1 - 2.6e-78 262.7 0.1 4.2e-78 262.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OWF38963.1 - 3.2e-20 71.7 0.1 6.3e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OWF38963.1 - 2.4e-15 56.6 0.1 5.5e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OWF38963.1 - 0.0014 18.4 0.4 0.73 9.7 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like SspB PF04386.13 OWF38963.1 - 0.033 14.1 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Stringent starvation protein B BUD22 PF09073.10 OWF38963.1 - 0.069 12.5 2.4 0.099 12.0 2.4 1.1 1 0 0 1 1 1 0 BUD22 Dehydrin PF00257.19 OWF38963.1 - 0.55 10.8 3.3 1 9.9 3.3 1.4 1 0 0 1 1 1 0 Dehydrin CAF1 PF04857.20 OWF38964.1 - 1.7e-76 257.5 0.0 9.6e-41 140.0 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease zf-CCCH PF00642.24 OWF38964.1 - 0.029 14.3 0.9 0.072 13.0 0.9 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ubiquitin PF00240.23 OWF38965.1 - 2.8e-05 23.8 0.2 7.3e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OWF38965.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ndc1_Nup PF09531.10 OWF38965.1 - 0.54 8.9 0.0 0.54 8.9 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup HLH PF00010.26 OWF38967.1 - 1.9e-10 40.5 0.1 3.4e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CENP-C_C PF11699.8 OWF38968.1 - 3.2 8.0 66.9 0.71 10.1 4.4 7.2 1 1 9 10 10 10 0 Mif2/CENP-C like AraC_binding PF02311.19 OWF38968.1 - 7.7 6.4 15.8 16 5.4 0.4 4.4 2 1 0 4 4 4 0 AraC-like ligand binding domain EF-hand_6 PF13405.6 OWF38969.1 - 1.4e-18 65.2 10.9 2.4e-05 23.9 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OWF38969.1 - 5.3e-18 63.2 16.0 9.5e-07 27.9 1.0 4.6 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF38969.1 - 1.4e-16 60.7 7.9 2.2e-07 31.2 3.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF38969.1 - 7.9e-13 47.3 10.0 7.5e-05 22.0 0.3 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF38969.1 - 9.4e-09 35.0 11.0 2.5e-06 27.3 3.8 3.7 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF38969.1 - 0.0049 17.2 0.4 2.4 8.5 0.0 2.8 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF38969.1 - 0.079 12.9 5.0 0.13 12.2 0.3 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand GH-E PF14410.6 OWF38969.1 - 0.12 12.8 0.2 6 7.3 0.1 2.5 1 1 1 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues EF-hand_9 PF14658.6 OWF38969.1 - 0.14 12.5 2.9 5.1 7.5 0.0 3.7 4 1 1 5 5 5 0 EF-hand domain Roc PF08477.13 OWF38970.1 - 7.1e-11 42.4 0.0 6.1e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF38970.1 - 8.2e-11 42.1 0.0 2.8e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 OWF38970.1 - 8.7e-08 31.9 0.1 0.0017 18.0 0.0 2.4 2 0 0 2 2 2 2 Ras family AAA_22 PF13401.6 OWF38970.1 - 0.00027 21.2 0.2 0.43 10.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain Arf PF00025.21 OWF38970.1 - 0.00043 19.8 0.2 0.007 15.8 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Death PF00531.22 OWF38970.1 - 0.003 17.7 0.0 0.0097 16.1 0.0 1.8 1 0 0 1 1 1 1 Death domain CENP-C_C PF11699.8 OWF38971.1 - 2.7e-17 62.7 0.0 1.3e-16 60.6 0.0 2.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 OWF38971.1 - 0.00021 21.0 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain HAUS-augmin3 PF14932.6 OWF38972.1 - 5.1e-49 167.2 12.9 5.1e-49 167.2 12.9 2.9 2 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.12 OWF38972.1 - 2.5 8.2 11.3 1.6 8.8 0.5 3.8 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 OWF38973.1 - 3.5e-46 157.7 0.0 6.6e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38973.1 - 1.9e-30 106.1 0.0 3.2e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PTEN_C2 PF10409.9 OWF38973.1 - 5.2e-18 65.1 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.31 OWF38973.1 - 1.1e-06 28.7 0.1 1.2e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Kinase-like PF14531.6 OWF38973.1 - 0.00019 20.9 0.0 0.076 12.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DSPc PF00782.20 OWF38973.1 - 0.0017 18.2 0.1 0.0044 16.8 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Haspin_kinase PF12330.8 OWF38973.1 - 0.025 13.5 0.0 0.025 13.5 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 OWF38973.1 - 0.15 12.0 0.0 0.86 9.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family GRP PF07172.11 OWF38973.1 - 2.6 8.8 9.9 4.8 7.9 7.2 2.6 2 0 0 2 2 2 0 Glycine rich protein family PRKCSH-like PF12999.7 OWF38974.1 - 1.7e-38 132.1 11.0 1.7e-38 132.1 11.0 2.4 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OWF38974.1 - 2.9e-26 92.0 0.1 7.7e-26 90.6 0.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OWF38974.1 - 1.9e-08 35.2 2.1 1.9e-08 35.2 2.1 2.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein EF-hand_1 PF00036.32 OWF38974.1 - 6.2e-06 25.4 1.7 0.049 13.2 0.1 3.0 1 1 1 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF38974.1 - 5.6e-05 22.7 0.4 0.28 11.2 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF38974.1 - 0.0002 21.8 3.4 0.00032 21.1 0.9 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF38974.1 - 0.00047 19.5 0.4 0.36 10.4 0.1 3.3 3 0 0 3 3 3 2 EF hand Ldl_recept_a PF00057.18 OWF38974.1 - 0.00063 19.9 9.9 0.044 14.0 0.5 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF2015 PF09435.10 OWF38974.1 - 0.59 10.0 3.8 0.56 10.1 0.4 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2015) DM PF00751.18 OWF38975.1 - 7.5e-22 77.0 13.7 1.2e-21 76.3 13.7 1.4 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 OWF38975.1 - 8.2e-17 60.5 0.1 1.6e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 DMRTA motif MiAMP1 PF09117.10 OWF38976.1 - 0.19 12.0 33.7 11 6.3 0.8 7.8 1 1 7 8 8 8 0 MiAMP1 DUF2288 PF10052.9 OWF38976.1 - 3.1 7.9 11.3 19 5.4 0.1 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF2288) AROS PF15684.5 OWF38976.1 - 6.3 7.4 57.3 37 4.9 5.4 6.0 1 1 3 4 4 4 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 AROS PF15684.5 OWF38977.1 - 0.49 11.0 9.3 4.6 7.8 9.3 2.2 1 1 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 MiAMP1 PF09117.10 OWF38977.1 - 1.5 9.1 8.1 7.3 6.9 1.7 2.5 1 1 1 2 2 2 0 MiAMP1 DUF5617 PF18493.1 OWF38977.1 - 1.6 8.9 13.8 53 4.0 0.5 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5617) SRI PF08236.11 OWF38977.1 - 2.4 8.4 18.7 4.4 7.6 18.7 1.5 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain DUF3562 PF12085.8 OWF38977.1 - 4 7.1 6.0 8.7 6.0 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3562) DUF4025 PF13217.6 OWF38977.1 - 9 6.2 17.4 32 4.5 1.3 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4025) DM PF00751.18 OWF38979.1 - 4.1e-23 81.0 10.7 6.4e-23 80.4 10.7 1.3 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 OWF38979.1 - 1.9e-19 68.9 0.3 3.8e-19 68.0 0.3 1.5 1 0 0 1 1 1 1 DMRTA motif CUE PF02845.16 OWF38979.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 CUE domain Anp1 PF03452.14 OWF38979.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Anp1 zf-H2C2_5 PF13909.6 OWF38980.1 - 1.5e-06 27.8 9.2 2.6e-06 27.1 1.7 2.8 2 1 1 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF38980.1 - 0.00037 20.8 7.7 0.0027 18.1 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Osteoregulin PF07175.11 OWF38980.1 - 0.0034 17.6 0.7 0.0034 17.6 0.7 1.7 1 1 1 2 2 2 1 Osteoregulin Pes-10 PF07149.11 OWF38980.1 - 0.62 9.1 2.1 0.84 8.6 2.1 1.1 1 0 0 1 1 1 0 Pes-10 UBX PF00789.20 OWF38983.1 - 7.6e-21 74.1 0.2 2e-20 72.8 0.2 1.8 1 0 0 1 1 1 1 UBX domain ubiquitin PF00240.23 OWF38983.1 - 3.4e-10 39.5 0.5 0.00063 19.4 0.1 3.5 3 0 0 3 3 3 2 Ubiquitin family UBA_4 PF14555.6 OWF38983.1 - 8.8e-05 22.2 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Ubiquitin_2 PF14560.6 OWF38983.1 - 0.13 12.7 0.5 37 4.9 0.0 3.5 3 0 0 3 3 3 0 Ubiquitin-like domain DUF1682 PF07946.14 OWF38983.1 - 0.28 10.3 11.3 0.45 9.7 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3523 PF12037.8 OWF38983.1 - 0.48 9.7 17.4 0.77 9.1 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DEAD PF00270.29 OWF38984.1 - 1.2e-48 165.2 0.1 1.8e-48 164.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF38984.1 - 1e-30 106.3 0.1 4e-29 101.2 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OWF38984.1 - 7.8e-07 28.5 0.1 1.2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OWF38984.1 - 4.2e-05 23.6 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OWF38984.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_19 PF13245.6 OWF38984.1 - 0.028 14.7 0.0 0.087 13.2 0.0 1.8 2 1 0 2 2 2 0 AAA domain PHF5 PF03660.14 OWF38985.1 - 2e-50 169.3 13.0 2.3e-50 169.2 13.0 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OWF38985.1 - 0.35 8.7 9.1 0.35 8.7 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 bZIP_1 PF00170.21 OWF38986.1 - 4.9e-09 36.2 5.6 8.1e-09 35.4 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF38986.1 - 2e-05 24.6 6.6 4.3e-05 23.5 6.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF38986.1 - 0.014 15.9 3.6 0.027 15.0 3.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor EOS1 PF12326.8 OWF38986.1 - 0.11 12.4 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein ADH_N PF08240.12 OWF38987.1 - 2.5e-22 78.8 3.0 7.1e-22 77.3 3.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OWF38987.1 - 1.1e-21 77.1 0.2 1.9e-21 76.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OWF38987.1 - 0.17 11.2 0.2 0.35 10.2 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EF-hand_7 PF13499.6 OWF38988.1 - 4.9e-17 62.1 11.1 3e-08 34.0 0.7 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF38988.1 - 1.2e-10 40.4 6.9 0.088 12.8 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF38988.1 - 2e-09 37.1 14.0 1.5e-05 24.7 2.9 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 OWF38988.1 - 1.1e-07 30.9 9.1 0.011 15.2 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF38988.1 - 5.8e-06 25.6 1.0 0.039 13.5 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 OWF38988.1 - 0.072 13.0 5.4 13 5.8 0.0 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand GH-E PF14410.6 OWF38988.1 - 0.094 13.1 0.0 14 6.2 0.0 2.4 1 1 1 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues EF-hand_6 PF13405.6 OWF38989.1 - 1.1e-13 49.9 1.9 1.3e-06 27.9 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 OWF38989.1 - 2.4e-12 45.4 1.5 2.3e-06 26.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OWF38989.1 - 6.9e-11 42.4 3.1 4.8e-07 30.1 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF38989.1 - 1.3e-07 31.4 3.4 1.5e-05 24.8 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF38989.1 - 9.3e-07 28.1 5.5 0.0009 18.6 0.1 2.9 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 OWF38989.1 - 0.0065 16.8 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OWF38989.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_4 PF12763.7 OWF38989.1 - 0.026 14.5 1.5 1.7 8.6 0.0 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 OWF38989.1 - 0.19 10.2 0.0 0.22 10.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) U-box PF04564.15 OWF38990.1 - 0.0004 20.5 8.5 0.94 9.7 0.7 3.4 1 1 2 3 3 3 3 U-box domain SICA_C PF12879.7 OWF38990.1 - 0.0008 19.4 5.0 0.78 9.8 0.2 3.1 1 1 2 3 3 3 3 SICA C-terminal inner membrane domain DOR PF14839.6 OWF38990.1 - 0.0081 16.2 25.1 1.3 9.0 3.2 3.9 1 1 2 3 3 3 3 DOR family La PF05383.17 OWF38990.1 - 0.12 12.5 0.4 30 4.8 0.0 3.1 3 1 0 4 4 4 0 La domain DUF956 PF06115.11 OWF38990.1 - 0.48 10.2 4.9 10 5.9 0.7 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF956) zf-CRD PF17979.1 OWF38990.1 - 0.93 9.6 11.2 5.8 7.0 2.9 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Ly49 PF08391.10 OWF38990.1 - 8.5 6.8 15.8 8 6.8 4.7 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region SICA_C PF12879.7 OWF38991.1 - 0.0015 18.5 9.2 1.6 8.7 2.0 4.5 1 1 1 2 2 2 2 SICA C-terminal inner membrane domain U-box PF04564.15 OWF38991.1 - 0.22 11.7 20.4 0.55 10.4 1.8 4.5 1 1 2 3 3 3 0 U-box domain DOR PF14839.6 OWF38991.1 - 0.33 10.9 40.0 3.9 7.4 7.3 5.0 1 1 2 3 3 3 0 DOR family DUF956 PF06115.11 OWF38991.1 - 1.2 8.9 10.8 11 5.8 1.3 4.2 1 1 2 3 3 3 0 Domain of unknown function (DUF956) Neur_chan_memb PF02932.16 OWF38993.1 - 3.1e-06 27.4 14.1 9.9e-06 25.8 13.2 1.9 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF4870 PF09685.10 OWF38993.1 - 0.067 13.3 5.5 0.026 14.6 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Neur_chan_LBD PF02931.23 OWF38994.1 - 2.2e-12 46.9 0.0 3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF38994.1 - 0.00082 19.5 3.9 0.0011 19.1 3.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF38995.1 - 1.4e-39 135.8 0.0 1.9e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF38995.1 - 1.1e-12 48.6 2.4 1.1e-12 48.6 2.4 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DSL PF01414.19 OWF38996.1 - 1.4e-16 60.5 78.8 6.7e-07 29.5 5.3 16.4 7 3 7 15 15 15 9 Delta serrate ligand EGF PF00008.27 OWF38996.1 - 1.6e-16 60.3 92.2 6e-07 29.7 9.0 19.9 18 3 1 19 19 19 8 EGF-like domain EGF_CA PF07645.15 OWF38996.1 - 2.8e-07 30.6 41.2 4.2e-05 23.7 9.9 15.1 4 2 11 15 15 15 4 Calcium-binding EGF domain hEGF PF12661.7 OWF38996.1 - 0.00041 20.9 15.7 0.0011 19.5 4.6 18.4 20 0 0 20 20 20 8 Human growth factor-like EGF cEGF PF12662.7 OWF38996.1 - 0.00047 20.0 1.5 0.00047 20.0 1.5 11.2 11 0 0 11 11 11 3 Complement Clr-like EGF-like EGF_2 PF07974.13 OWF38996.1 - 0.002 18.5 7.4 0.002 18.5 7.4 20.8 19 3 1 20 20 20 11 EGF-like domain 7tm_1 PF00001.21 OWF38997.1 - 5.6e-43 147.2 15.4 6.5e-43 147.0 15.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF38997.1 - 2.9e-06 26.9 14.2 3.9e-06 26.4 14.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF38997.1 - 0.0053 16.5 7.5 0.1 12.3 6.6 2.4 1 1 0 1 1 1 1 Olfactory receptor Pkinase PF00069.25 OWF38998.1 - 1.7e-67 227.6 0.0 2.8e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF38998.1 - 6.9e-42 143.5 0.0 1.9e-41 142.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF38998.1 - 6.9e-11 42.0 0.0 2.3e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OWF38998.1 - 0.00031 20.2 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF38998.1 - 0.0019 17.2 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 OWF38998.1 - 0.063 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 OWF38998.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Act-Frag_cataly PF09192.10 OWF38998.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Aconitase PF00330.20 OWF38999.1 - 1.6e-150 502.2 0.0 2e-150 501.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OWF38999.1 - 8.9e-46 155.5 0.0 2.5e-45 154.0 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain Glycos_transf_2 PF00535.26 OWF39000.1 - 1.1e-27 96.9 0.0 2.3e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OWF39000.1 - 4.2e-06 26.4 0.1 2.3e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF39000.1 - 0.0032 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CorA PF01544.18 OWF39000.1 - 0.026 13.8 1.7 0.051 12.9 1.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FAM184 PF15665.5 OWF39000.1 - 0.11 12.3 1.8 0.17 11.6 1.8 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Het-C PF07217.11 OWF39000.1 - 0.63 8.5 4.4 5.6 5.4 0.2 2.0 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C MMR_HSR1 PF01926.23 OWF39001.1 - 2.5e-05 24.3 0.0 8.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OWF39001.1 - 0.0023 17.2 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit PRK PF00485.18 OWF39001.1 - 0.0057 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 OWF39001.1 - 0.0072 16.0 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OWF39001.1 - 0.008 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 OWF39001.1 - 0.011 15.1 0.0 0.028 13.7 0.0 1.7 1 1 0 1 1 1 0 Septin AIG1 PF04548.16 OWF39001.1 - 0.024 14.0 0.2 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 AIG1 family IIGP PF05049.13 OWF39001.1 - 0.029 13.4 0.2 0.053 12.6 0.0 1.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 OWF39001.1 - 0.088 13.3 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter DUF3535 PF12054.8 OWF39002.1 - 4e-112 375.6 1.4 6.7e-110 368.3 0.2 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OWF39002.1 - 2.2e-62 210.8 0.3 6.9e-62 209.2 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF39002.1 - 6.8e-17 61.8 0.0 1.9e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 OWF39002.1 - 3.6e-16 57.9 11.1 0.062 13.6 0.2 9.4 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 OWF39002.1 - 3.4e-08 33.8 5.9 0.25 11.8 0.1 5.6 4 1 1 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 OWF39002.1 - 1e-05 25.9 12.6 0.26 11.8 0.2 7.5 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OWF39002.1 - 0.00039 21.0 0.0 3.3 8.4 0.0 4.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Neurochondrin PF05536.11 OWF39002.1 - 0.028 12.8 0.7 0.061 11.7 0.7 1.5 1 0 0 1 1 1 0 Neurochondrin Adaptin_N PF01602.20 OWF39002.1 - 0.077 11.5 10.3 3.7 6.0 0.1 3.7 2 1 0 2 2 2 0 Adaptin N terminal region Arm PF00514.23 OWF39002.1 - 0.92 9.6 6.4 6.7 6.9 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat SIR2 PF02146.17 OWF39003.1 - 2e-26 93.0 1.1 5.5e-26 91.6 1.1 1.8 1 1 0 1 1 1 1 Sir2 family MTHFR_C PF12225.8 OWF39003.1 - 0.49 10.1 4.7 0.26 10.9 0.8 2.4 1 1 1 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Trypsin PF00089.26 OWF39004.1 - 1.2e-63 214.9 3.7 1.3e-63 214.8 3.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF39004.1 - 4.8e-07 30.8 0.1 1.1e-06 29.7 0.1 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF39004.1 - 0.0064 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 OWF39004.1 - 0.009 15.6 0.0 0.088 12.4 0.0 2.0 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 7tm_1 PF00001.21 OWF39005.1 - 3.5e-51 174.0 10.4 4.4e-51 173.7 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF39005.1 - 1e-15 57.8 10.7 1.4e-15 57.3 10.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF39005.1 - 7e-05 22.6 10.7 7e-05 22.6 10.7 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Na_H_antiport_1 PF06965.12 OWF39005.1 - 0.0002 20.4 2.2 0.0002 20.4 2.2 1.8 2 0 0 2 2 2 1 Na+/H+ antiporter 1 Git3 PF11710.8 OWF39005.1 - 0.066 13.0 8.7 0.15 11.8 8.7 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF2116 PF09889.9 OWF39005.1 - 0.074 13.0 2.5 0.59 10.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DHHC PF01529.20 OWF39005.1 - 5.2 7.2 12.5 14 5.8 3.6 3.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase 7TM_GPCR_Srbc PF10316.9 OWF39005.1 - 8.8 5.7 18.7 0.12 11.9 11.1 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc NES_C_h PF18208.1 OWF39007.1 - 0.094 13.0 0.7 0.2 12.0 0.7 1.5 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain DBD_Tnp_Hermes PF10683.9 OWF39007.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain LSM_int_assoc PF16605.5 OWF39008.1 - 0.039 14.1 0.2 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 LSM-interacting associated unstructured Fucosidase_C PF16757.5 OWF39009.1 - 5.4e-07 30.1 10.5 72 4.1 0.3 11.0 1 1 16 17 17 17 1 Alpha-L-fucosidase C-terminal domain CH PF00307.31 OWF39011.1 - 5e-12 46.0 0.1 9.1e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.17 OWF39011.1 - 1.7e-09 37.7 0.0 8.6e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 EB1-like C-terminal motif CAMSAP_CH PF11971.8 OWF39011.1 - 0.0021 17.9 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain Tropomyosin PF00261.20 OWF39012.1 - 2.5e-86 288.9 70.4 6.7e-82 274.4 48.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 OWF39012.1 - 1.2e-36 126.0 59.5 6e-30 104.3 33.0 2.3 2 0 0 2 2 2 2 Tropomyosin like MscS_porin PF12795.7 OWF39012.1 - 2.7e-06 27.1 48.1 0.011 15.3 20.6 3.1 1 1 2 3 3 3 3 Mechanosensitive ion channel porin domain DUF724 PF05266.14 OWF39012.1 - 8e-06 25.8 42.9 0.00057 19.8 14.9 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF724) EzrA PF06160.12 OWF39012.1 - 1.5e-05 23.4 44.7 0.013 13.7 8.3 2.6 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Laminin_II PF06009.12 OWF39012.1 - 1.6e-05 25.0 41.3 0.00096 19.2 9.0 4.2 1 1 4 5 5 5 3 Laminin Domain II DUF1664 PF07889.12 OWF39012.1 - 3.3e-05 23.9 29.7 0.0069 16.4 8.2 3.5 1 1 1 3 3 3 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 OWF39012.1 - 0.00025 21.4 55.5 0.0022 18.3 16.5 3.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) FPP PF05911.11 OWF39012.1 - 0.00046 18.5 48.8 0.13 10.5 24.0 2.5 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 OWF39012.1 - 0.00073 18.3 44.7 0.001 17.9 25.6 2.1 1 1 1 2 2 2 1 AAA domain Cep57_CLD PF14073.6 OWF39012.1 - 0.0021 18.1 15.7 0.0021 18.1 15.7 3.6 1 1 2 3 3 3 1 Centrosome localisation domain of Cep57 Spc7 PF08317.11 OWF39012.1 - 0.0027 16.7 55.2 0.027 13.3 29.3 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 OWF39012.1 - 0.0036 15.2 54.8 0.027 12.3 14.5 2.1 1 1 1 2 2 2 2 Myosin tail Cep57_CLD_2 PF14197.6 OWF39012.1 - 0.0038 17.3 11.5 0.0038 17.3 11.5 5.4 2 2 2 4 4 2 1 Centrosome localisation domain of PPC89 Gp58 PF07902.11 OWF39012.1 - 0.0047 15.3 2.9 0.0047 15.3 2.9 2.5 1 1 2 3 3 3 1 gp58-like protein DUF16 PF01519.16 OWF39012.1 - 0.0057 17.1 5.9 0.0057 17.1 5.9 4.5 1 1 2 3 3 3 1 Protein of unknown function DUF16 Filament PF00038.21 OWF39012.1 - 0.0057 16.3 49.0 0.0079 15.8 11.7 3.7 1 1 1 3 3 3 2 Intermediate filament protein DUF4200 PF13863.6 OWF39012.1 - 0.0061 17.0 20.6 0.0061 17.0 20.6 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4200) XhlA PF10779.9 OWF39012.1 - 0.008 16.4 44.6 0.45 10.8 0.9 6.3 2 2 5 7 7 7 1 Haemolysin XhlA CCDC144C PF14915.6 OWF39012.1 - 0.0095 15.1 50.0 0.029 13.5 50.0 1.6 1 1 0 1 1 1 1 CCDC144C protein coiled-coil region Fib_alpha PF08702.10 OWF39012.1 - 0.0098 16.1 35.1 0.03 14.5 4.6 3.5 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 OWF39012.1 - 0.01 16.1 5.5 0.01 16.1 5.5 4.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 OWF39012.1 - 0.011 15.8 8.5 0.011 15.8 8.5 4.1 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase CLZ PF16526.5 OWF39012.1 - 0.012 15.9 8.5 0.012 15.9 8.5 5.6 2 2 4 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 OWF39012.1 - 0.016 15.7 46.7 0.053 14.0 15.8 2.7 1 1 1 2 2 2 0 Fez1 DUF3450 PF11932.8 OWF39012.1 - 0.016 14.5 46.5 0.22 10.8 8.6 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) OmpH PF03938.14 OWF39012.1 - 0.018 15.4 20.7 0.018 15.4 20.7 4.0 1 1 2 3 3 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 OWF39012.1 - 0.018 15.4 0.9 0.018 15.4 0.9 6.6 3 3 6 9 9 8 0 Flagella accessory protein C (FlaC) HOOK PF05622.12 OWF39012.1 - 0.019 13.1 52.7 0.017 13.3 10.2 3.0 1 1 0 1 1 1 0 HOOK protein DUF3584 PF12128.8 OWF39012.1 - 0.024 12.2 50.4 1.2 6.5 50.4 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.16 OWF39012.1 - 0.028 14.6 43.4 0.19 12.0 14.9 3.7 2 2 2 4 4 4 0 Flagellar FliJ protein DUF4472 PF14739.6 OWF39012.1 - 0.037 14.7 43.2 2.1 9.1 7.7 4.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4472) Baculo_PEP_C PF04513.12 OWF39012.1 - 0.04 13.9 28.0 0.047 13.7 9.5 3.5 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.10 OWF39012.1 - 0.045 14.1 42.5 0.18 12.2 4.6 4.4 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) FH2 PF02181.23 OWF39012.1 - 0.048 12.8 34.2 0.15 11.2 7.3 3.1 1 1 2 3 3 3 0 Formin Homology 2 Domain Lebercilin PF15619.6 OWF39012.1 - 0.061 13.0 54.8 0.36 10.5 15.2 3.5 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ABC_tran_CTD PF16326.5 OWF39012.1 - 0.068 13.4 52.1 0.51 10.6 8.2 5.4 1 1 4 5 5 5 0 ABC transporter C-terminal domain CC2-LZ PF16516.5 OWF39012.1 - 0.076 13.4 44.8 0.97 9.8 14.6 5.1 1 1 4 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ERM PF00769.19 OWF39012.1 - 0.084 12.7 60.8 0.45 10.3 20.3 2.7 1 1 0 2 2 2 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 OWF39012.1 - 0.11 12.7 42.5 0.33 11.2 1.9 4.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 OWF39012.1 - 0.11 12.5 51.6 0.26 11.4 13.0 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.13 OWF39012.1 - 0.13 11.9 41.1 0.34 10.6 11.9 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF745) IFT57 PF10498.9 OWF39012.1 - 0.14 11.1 39.2 0.14 11.1 16.2 3.1 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 SH3BP5 PF05276.14 OWF39012.1 - 0.14 11.9 36.8 2.6 7.8 8.6 3.6 1 1 2 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) DMPK_coil PF08826.10 OWF39012.1 - 0.15 12.2 35.8 1 9.5 1.6 5.4 4 2 1 5 5 5 0 DMPK coiled coil domain like DUF3142 PF11340.8 OWF39012.1 - 0.16 11.7 3.1 0.41 10.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) DUF812 PF05667.11 OWF39012.1 - 0.18 10.7 49.6 0.12 11.2 23.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) OEP PF02321.18 OWF39012.1 - 0.22 11.3 44.8 0.3 10.9 7.3 4.2 2 2 2 4 4 4 0 Outer membrane efflux protein HemX PF04375.14 OWF39012.1 - 0.26 10.5 45.8 0.42 9.8 16.5 3.1 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase GAS PF13851.6 OWF39012.1 - 0.4 10.0 55.3 1.5 8.2 31.7 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OWF39012.1 - 0.4 10.7 59.3 3.6 7.7 12.8 4.2 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 OWF39012.1 - 0.4 10.1 51.1 0.6 9.5 16.1 2.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 BORCS7 PF16088.5 OWF39012.1 - 0.48 10.7 22.2 0.35 11.1 0.5 4.1 1 1 2 4 4 4 0 BLOC-1-related complex sub-unit 7 Laminin_I PF06008.14 OWF39012.1 - 0.56 9.9 46.2 2.2 7.9 9.1 3.9 1 1 1 2 2 2 0 Laminin Domain I Exonuc_VII_L PF02601.15 OWF39012.1 - 0.58 9.7 36.3 1.8 8.0 16.9 2.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit HiaBD2 PF15403.6 OWF39012.1 - 0.66 10.4 12.0 3 8.3 0.1 4.3 4 1 1 5 5 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) SlyX PF04102.12 OWF39012.1 - 0.69 10.6 40.7 5.2 7.8 5.6 5.5 3 2 3 6 6 6 0 SlyX Sugarporin_N PF11471.8 OWF39012.1 - 0.79 9.7 33.1 0.12 12.4 2.6 6.3 4 1 1 6 6 6 0 Maltoporin periplasmic N-terminal extension CALCOCO1 PF07888.11 OWF39012.1 - 0.87 8.4 52.9 0.32 9.8 33.1 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Rab5-bind PF09311.11 OWF39012.1 - 0.88 8.9 46.3 0.15 11.4 13.6 3.3 1 1 2 3 3 2 0 Rabaptin-like protein CENP-F_leu_zip PF10473.9 OWF39012.1 - 1.2 9.2 56.3 6.2 6.8 26.4 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ISG65-75 PF11727.8 OWF39012.1 - 1.5 8.0 38.3 0.49 9.6 8.5 3.1 1 1 2 3 3 3 0 Invariant surface glycoprotein Prefoldin PF02996.17 OWF39012.1 - 1.6 8.7 46.3 0.75 9.7 3.5 6.2 1 1 5 6 6 6 0 Prefoldin subunit DASH_Hsk3 PF08227.11 OWF39012.1 - 1.8 9.0 12.6 3.4 8.1 0.4 4.2 5 0 0 5 5 3 0 DASH complex subunit Hsk3 like TMF_DNA_bd PF12329.8 OWF39012.1 - 2.1 8.4 56.6 0.072 13.1 8.4 5.9 1 1 3 5 5 4 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 OWF39012.1 - 2.3 8.2 49.5 0.73 9.8 4.9 6.5 2 2 3 5 5 4 0 Prefoldin subunit DHR10 PF18595.1 OWF39012.1 - 3.2 7.8 60.6 3.1 7.9 10.3 5.0 1 1 4 5 5 5 0 Designed helical repeat protein 10 domain APG17 PF04108.12 OWF39012.1 - 3.2 6.8 34.2 7.8 5.5 7.8 3.2 1 1 2 3 3 3 0 Autophagy protein Apg17 DUF2968 PF11180.8 OWF39012.1 - 3.3 7.3 41.8 0.024 14.3 12.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) DUF4763 PF15960.5 OWF39012.1 - 3.7 6.8 34.5 0.57 9.4 13.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Vps5 PF09325.10 OWF39012.1 - 3.8 7.0 39.1 0.58 9.7 4.3 4.8 1 1 4 5 5 5 0 Vps5 C terminal like T3SSipB PF16535.5 OWF39012.1 - 4 7.9 41.8 14 6.1 18.2 3.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB FOXP-CC PF16159.5 OWF39012.1 - 4.7 7.9 16.0 0.74 10.5 0.6 3.9 3 2 1 5 5 2 0 FOXP coiled-coil domain RasGAP_C PF03836.15 OWF39012.1 - 5.1 7.2 26.7 0.31 11.2 3.9 3.0 1 1 2 3 3 3 0 RasGAP C-terminus MAD PF05557.13 OWF39012.1 - 5.6 5.2 52.5 0.71 8.2 19.4 2.3 1 1 2 3 3 3 0 Mitotic checkpoint protein PI3K_P85_iSH2 PF16454.5 OWF39012.1 - 6.1 6.4 38.9 7.8 6.1 12.0 4.1 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HMMR_N PF15905.5 OWF39012.1 - 6.3 6.2 53.0 30 4.0 28.6 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Uso1_p115_C PF04871.13 OWF39012.1 - 6.4 7.2 57.1 0.21 11.9 11.0 4.0 1 1 2 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMPIT PF07851.13 OWF39012.1 - 9 5.4 39.3 0.61 9.3 7.8 3.1 1 1 2 3 3 3 0 TMPIT-like protein DUF5082 PF16888.5 OWF39012.1 - 9.7 6.5 34.4 0.078 13.2 3.3 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Dioxygenase_C PF00775.21 OWF39013.1 - 2.7e-05 23.7 0.0 8.9 5.7 0.0 4.9 2 1 2 4 4 4 3 Dioxygenase LisH_2 PF16045.5 OWF39013.1 - 0.09 11.8 48.5 11 5.1 0.0 14.5 17 0 0 17 17 17 0 LisH I-set PF07679.16 OWF39014.1 - 1.2e-11 44.5 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF39014.1 - 7.2e-10 39.3 0.1 1.4e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 OWF39014.1 - 2.5e-08 34.0 0.2 4.6e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF39014.1 - 2.7e-05 24.4 0.2 4.7e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 OWF39014.1 - 0.00076 19.6 0.2 0.05 13.8 0.2 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain C1-set PF07654.15 OWF39014.1 - 0.0016 18.8 1.1 0.0024 18.2 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 OWF39014.1 - 0.29 11.1 1.9 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Phosphodiest PF01663.22 OWF39015.1 - 7.1e-12 45.6 0.5 2e-11 44.1 0.1 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF39015.1 - 3.5e-07 29.9 0.1 5.9e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 OWF39015.1 - 0.00037 19.9 0.1 0.00065 19.1 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1634 PF07843.11 OWF39015.1 - 0.011 15.8 2.6 0.011 15.8 2.6 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1634) zf-MYND PF01753.18 OWF39016.1 - 1.1e-06 28.7 11.6 2.7e-06 27.3 11.6 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OWF39016.1 - 0.42 10.8 6.5 1.5 9.0 6.5 2.0 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ammonium_transp PF00909.21 OWF39017.1 - 4.2e-113 378.1 27.2 5.2e-113 377.8 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family 7tm_6 PF02949.20 OWF39017.1 - 0.34 9.9 2.5 0.65 9.0 2.5 1.4 1 0 0 1 1 1 0 7tm Odorant receptor LRR_8 PF13855.6 OWF39019.1 - 3.9e-11 42.5 10.5 8.1e-07 28.7 2.8 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF39019.1 - 8.2e-06 26.1 10.0 0.23 11.9 0.2 3.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT PF01462.18 OWF39019.1 - 0.00012 21.7 3.8 0.00012 21.7 3.8 3.3 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 OWF39019.1 - 0.0059 16.1 2.5 0.36 10.3 1.1 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OWF39019.1 - 0.087 13.4 4.8 11 7.1 0.0 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF39019.1 - 0.95 9.7 5.2 4.1 7.7 0.9 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Ribosomal_L10 PF00466.20 OWF39020.1 - 0.046 13.9 3.0 0.1 12.8 3.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L10 ADAM_spacer1 PF05986.14 OWF39022.1 - 4.4e-27 94.4 0.0 7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 OWF39022.1 - 1.3e-23 82.9 88.6 2.7e-06 27.5 6.5 7.8 6 2 0 6 6 6 6 Thrombospondin type 1 domain Myosin_head PF00063.21 OWF39023.1 - 2.6e-252 838.9 2.3 3.4e-252 838.6 2.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OWF39023.1 - 1.2e-51 175.0 0.2 2.4e-51 174.1 0.2 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 OWF39023.1 - 4.2e-15 55.3 0.1 2.2e-14 53.1 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OWF39023.1 - 5.4e-15 54.7 0.1 1.3e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF39023.1 - 2.1e-09 36.9 0.0 6.5e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 OWF39023.1 - 0.045 13.6 2.7 0.14 12.0 2.7 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF3729 PF12526.8 OWF39023.1 - 5.3 8.6 11.8 13 7.4 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) LRR_8 PF13855.6 OWF39024.1 - 2.6e-24 84.8 42.7 2.6e-09 36.7 6.8 4.5 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OWF39024.1 - 2e-12 47.1 34.7 0.00022 21.6 2.2 5.4 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF39024.1 - 0.039 13.9 0.2 5.6 6.9 0.0 2.7 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF39024.1 - 0.053 13.0 11.1 1.2 8.6 2.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 OWF39024.1 - 1.1 10.1 32.1 0.8 10.5 0.4 7.9 8 1 0 8 8 8 0 Leucine Rich Repeat UPF1_Zn_bind PF09416.10 OWF39025.1 - 6.4e-75 250.3 3.1 1.2e-74 249.4 1.9 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 OWF39025.1 - 7.6e-60 201.9 0.0 1.5e-59 200.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OWF39025.1 - 2.6e-49 168.4 4.2 4.4e-28 98.8 0.4 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 OWF39025.1 - 5.2e-35 119.6 0.0 1e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OWF39025.1 - 5.1e-14 52.4 0.0 7.3e-12 45.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OWF39025.1 - 1.5e-09 38.3 0.0 7.2e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OWF39025.1 - 1.1e-05 25.6 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OWF39025.1 - 7.8e-05 22.5 0.1 0.41 10.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OWF39025.1 - 0.0001 21.7 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 OWF39025.1 - 0.00017 21.5 0.0 0.00044 20.1 0.0 1.8 1 0 0 1 1 1 1 Helicase ATPase PF06745.13 OWF39025.1 - 0.0081 15.5 0.0 0.072 12.4 0.0 2.0 2 0 0 2 2 2 1 KaiC SRP54 PF00448.22 OWF39025.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.29 OWF39025.1 - 0.015 15.1 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 OWF39025.1 - 0.015 14.8 1.1 0.074 12.6 0.0 2.4 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 OWF39025.1 - 0.023 15.0 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF39025.1 - 0.035 14.5 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 OWF39025.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.7 OWF39025.1 - 0.09 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 OWF39025.1 - 0.18 12.3 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T4_deiodinase PF00837.17 OWF39026.1 - 7.7e-37 126.8 0.1 8.9e-37 126.6 0.1 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Zip PF02535.22 OWF39027.1 - 1.4e-52 179.0 9.7 1.6e-52 178.8 9.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2202 PF09968.9 OWF39027.1 - 0.037 13.9 0.3 0.18 11.7 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) TraG_N PF07916.11 OWF39027.1 - 0.1 11.4 4.2 0.23 10.3 3.5 1.8 2 0 0 2 2 2 0 TraG-like protein, N-terminal region CNOT1_TTP_bind PF16417.5 OWF39027.1 - 0.12 11.5 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF202 PF02656.15 OWF39027.1 - 0.9 10.0 7.0 25 5.4 1.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF202) PALP PF00291.25 OWF39028.1 - 2e-73 247.4 0.2 2.2e-73 247.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.22 OWF39029.1 - 4.4e-20 70.7 6.9 7.7e-07 28.6 0.4 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat NinF PF05810.12 OWF39029.1 - 0.046 13.6 0.4 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 NinF protein PDCD7 PF16021.5 OWF39030.1 - 3.4e-77 259.6 29.6 3.4e-77 259.6 29.6 1.7 2 0 0 2 2 2 1 Programmed cell death protein 7 MOSC PF03473.17 OWF39030.1 - 1.4 8.9 4.6 1.3 9.0 2.2 2.3 2 1 0 2 2 2 0 MOSC domain N6-adenineMlase PF10237.9 OWF39031.1 - 8.1e-22 77.7 0.7 1.5e-21 76.9 0.7 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase SET PF00856.28 OWF39033.1 - 5.1e-17 62.8 0.4 5.1e-17 62.8 0.4 3.8 2 2 0 2 2 2 1 SET domain BAH PF01426.18 OWF39033.1 - 6.1e-16 58.4 0.1 4.1e-15 55.7 0.1 2.3 2 0 0 2 2 2 1 BAH domain Bromodomain PF00439.25 OWF39033.1 - 7.4e-15 54.8 0.2 2.8e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Bromodomain AWS PF17907.1 OWF39033.1 - 1.7e-14 53.5 6.9 1.7e-14 53.5 6.9 2.7 3 0 0 3 3 3 1 AWS domain PHD PF00628.29 OWF39033.1 - 0.00022 21.1 11.3 0.00022 21.1 11.3 2.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 OWF39033.1 - 0.94 9.1 6.8 2.1 8.0 6.8 1.7 1 0 0 1 1 1 0 PHD-finger DAP3 PF10236.9 OWF39034.1 - 1.3e-55 188.8 0.0 1.7e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OWF39034.1 - 0.0029 18.0 0.0 0.0069 16.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OWF39034.1 - 0.02 14.8 0.2 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 NACHT domain DUF4692 PF15763.5 OWF39034.1 - 0.1 13.0 2.6 0.22 12.0 2.6 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) MRI PF15325.6 OWF39034.1 - 0.45 11.6 5.1 0.92 10.6 5.1 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Herpes_pp85 PF04637.12 OWF39034.1 - 0.72 8.2 4.2 13 4.0 4.1 2.1 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) INCA1 PF15142.6 OWF39035.1 - 0.00028 21.0 1.6 0.0003 20.9 0.7 1.6 1 1 0 1 1 1 1 INCA1 Antiterm PF03589.13 OWF39035.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 Antitermination protein Kinesin PF00225.23 OWF39036.1 - 1.4e-101 339.8 0.5 1.4e-101 339.8 0.5 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF39036.1 - 7.2e-44 149.3 0.5 9.2e-43 145.7 0.2 3.2 2 0 0 2 2 2 1 Microtubule binding FBPase PF00316.20 OWF39037.1 - 5.3e-74 247.8 0.3 7e-74 247.4 0.3 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OWF39037.1 - 0.0099 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family DCX PF03607.17 OWF39037.1 - 0.03 14.4 0.0 11 6.2 0.0 2.7 2 1 0 2 2 2 0 Doublecortin WD40 PF00400.32 OWF39038.1 - 2.8e-21 75.4 14.7 6.3e-07 30.0 0.2 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OWF39038.1 - 8.8e-06 24.9 0.7 0.1 11.5 0.1 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OWF39038.1 - 0.00045 19.0 0.1 0.0022 16.7 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OWF39038.1 - 0.0085 16.4 0.0 7.4 6.9 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TENA_THI-4 PF03070.16 OWF39039.1 - 2.8e-10 40.4 0.2 4.6e-10 39.7 0.2 1.4 1 1 0 1 1 1 1 TENA/THI-4/PQQC family TRIQK PF15168.6 OWF39039.1 - 0.11 12.5 0.6 6.6 6.7 0.0 3.0 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF5612 PF18462.1 OWF39040.1 - 1.5 8.6 35.2 0.66 9.8 1.1 5.4 1 1 4 6 6 6 0 Domain of unknown function (DUF5612) Spc7 PF08317.11 OWF39040.1 - 3.2 6.6 5.6 7.1 5.4 0.2 3.3 1 1 3 4 4 4 0 Spc7 kinetochore protein TENA_THI-4 PF03070.16 OWF39041.1 - 1.3e-08 34.9 1.0 2.4e-08 34.0 1.0 1.4 1 1 0 1 1 1 1 TENA/THI-4/PQQC family TENA_THI-4 PF03070.16 OWF39042.1 - 4.9e-06 26.5 0.3 7e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PAH PF02671.21 OWF39043.1 - 3.8e-06 26.9 4.5 4.4e-05 23.5 0.6 2.9 2 0 0 2 2 2 1 Paired amphipathic helix repeat Myb_DNA-binding PF00249.31 OWF39043.1 - 7.8e-06 26.0 0.1 3.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF39043.1 - 1.3e-05 25.4 0.0 0.012 15.8 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain IFT20 PF14931.6 OWF39043.1 - 0.95 9.6 7.7 1.4 9.2 5.9 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 CoA_transf_3 PF02515.17 OWF39044.1 - 1.5e-74 251.4 0.0 3.6e-74 250.1 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III BTB PF00651.31 OWF39046.1 - 1.6e-21 76.6 1.6 6.2e-21 74.7 1.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF39046.1 - 2.3e-06 27.6 0.5 3.1e-05 24.0 0.0 2.7 4 0 0 4 4 4 1 BTB And C-terminal Kelch LRRC37AB_C PF14914.6 OWF39047.1 - 0.016 15.1 0.1 0.021 14.7 0.1 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain EssA PF10661.9 OWF39047.1 - 0.045 13.6 0.1 0.061 13.2 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Reo_sigma1 PF01664.16 OWF39048.1 - 0.00095 18.5 0.7 54 3.0 0.0 6.7 2 1 0 6 6 6 1 Reovirus viral attachment protein sigma 1 Glyco_hydro_42C PF08533.10 OWF39048.1 - 0.0014 18.3 3.9 38 4.1 0.0 7.5 4 0 0 4 4 4 2 Beta-galactosidase C-terminal domain Mito_fiss_reg PF05308.11 OWF39050.1 - 4.5 7.3 13.2 0.49 10.4 6.8 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 OWF39050.1 - 9.5 5.6 11.2 16 4.8 11.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Herpes_UL37_2 PF07413.11 OWF39053.1 - 0.1 11.8 1.1 0.13 11.4 1.1 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 BES1_N PF05687.13 OWF39053.1 - 0.29 11.5 3.9 0.5 10.8 3.9 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal SDF PF00375.18 OWF39054.1 - 8.9e-124 413.4 31.1 1e-123 413.2 31.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Rad60-SLD PF11976.8 OWF39055.1 - 1e-20 73.3 0.3 1.3e-20 73.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OWF39055.1 - 8.9e-15 54.2 0.2 1.1e-14 53.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Citrate_bind PF16114.5 OWF39056.1 - 8.6e-93 308.8 0.1 1.4e-92 308.1 0.1 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 OWF39056.1 - 4e-22 78.8 0.0 3.6e-19 69.1 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 OWF39056.1 - 9e-18 64.6 0.1 2e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 OWF39056.1 - 1.6e-12 47.9 0.0 4e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 OWF39056.1 - 1.7e-09 37.5 0.0 3.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 OWF39056.1 - 5.9e-06 26.1 0.0 2.3e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L27e PF01777.18 OWF39057.1 - 2.1e-36 124.1 10.0 2.9e-36 123.7 10.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OWF39057.1 - 1.2e-05 25.1 0.4 2.4e-05 24.1 0.4 1.6 1 0 0 1 1 1 1 KOW motif Amidohydro_2 PF04909.14 OWF39058.1 - 9.9e-67 225.7 0.0 1.1e-66 225.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase SNF2_N PF00176.23 OWF39059.1 - 3.5e-27 95.0 0.0 6.6e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HARP PF07443.13 OWF39059.1 - 2.8e-21 74.9 0.1 7.2e-21 73.6 0.1 1.8 1 0 0 1 1 1 1 HepA-related protein (HARP) Helicase_C PF00271.31 OWF39059.1 - 2.8e-13 50.2 0.1 8.2e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF39059.1 - 9.7e-07 28.9 0.7 0.00021 21.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OWF39059.1 - 0.0082 15.4 0.0 0.021 14.1 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1128 PF06569.11 OWF39059.1 - 0.022 14.7 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Flavi_DEAD PF07652.14 OWF39059.1 - 0.025 14.6 0.1 0.067 13.2 0.0 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF2924 PF11149.8 OWF39059.1 - 1.5 9.2 3.6 7.1 7.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) zf-C2H2_2 PF12756.7 OWF39060.1 - 1.1e-31 109.1 25.4 6.7e-27 93.8 6.1 3.6 3 1 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OWF39060.1 - 7.1e-09 35.7 11.5 1.3e-07 31.7 8.9 4.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF39060.1 - 7.7e-06 26.1 6.0 7.7e-06 26.1 6.0 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OWF39060.1 - 0.07 14.0 1.1 0.07 14.0 1.1 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger DUF1460 PF07313.12 OWF39060.1 - 0.097 12.1 3.2 0.16 11.3 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1460) THAP PF05485.12 OWF39060.1 - 0.45 11.5 6.3 1.1 10.3 5.3 2.3 1 1 0 1 1 1 0 THAP domain Connexin40_C PF16791.5 OWF39060.1 - 0.68 11.2 6.5 2.3 9.5 6.5 1.9 1 0 0 1 1 1 0 Connexin 40 C-terminal domain zf-LYAR PF08790.11 OWF39060.1 - 0.75 9.7 8.7 3.3 7.7 0.4 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Ribosomal_L37ae PF01780.19 OWF39061.1 - 2.7e-40 136.3 13.9 3.1e-40 136.2 13.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.10 OWF39061.1 - 0.025 14.3 1.6 0.031 14.0 1.6 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain Rsm1 PF08600.10 OWF39061.1 - 0.026 14.7 1.1 0.033 14.3 0.6 1.4 1 1 0 1 1 1 0 Rsm1-like MRNIP PF15749.5 OWF39061.1 - 0.12 13.1 6.8 2.8 8.7 3.8 2.5 1 1 1 2 2 2 0 MRN-interacting protein Zn_Tnp_IS1595 PF12760.7 OWF39061.1 - 0.33 11.0 6.7 0.61 10.1 6.7 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NCD3G PF07562.14 OWF39061.1 - 0.4 10.7 6.3 0.9 9.6 6.3 1.6 1 1 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR CarbpepA_inh PF02977.15 OWF39061.1 - 0.4 10.5 7.5 0.55 10.1 0.6 2.9 2 1 1 3 3 3 0 Carboxypeptidase A inhibitor MTABC_N PF16185.5 OWF39062.1 - 4.1e-80 268.8 7.7 4.1e-80 268.8 7.7 2.0 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_membrane PF00664.23 OWF39062.1 - 6.6e-38 130.9 6.8 6.6e-38 130.9 6.8 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 OWF39062.1 - 2.2e-35 122.2 0.0 4.3e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF39062.1 - 5.2e-08 32.6 0.3 1.4e-07 31.2 0.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OWF39062.1 - 0.00036 20.2 0.0 0.0021 17.8 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OWF39062.1 - 0.001 19.5 0.1 0.0022 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF39062.1 - 0.0051 17.1 0.0 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OWF39062.1 - 0.0058 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 OWF39062.1 - 0.009 16.5 0.4 0.02 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OWF39062.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TPR_11 PF13414.6 OWF39062.1 - 0.034 13.8 1.2 0.042 13.5 0.3 1.7 2 0 0 2 2 2 0 TPR repeat AAA_21 PF13304.6 OWF39062.1 - 0.05 13.4 0.2 0.19 11.5 0.1 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OWF39062.1 - 0.054 13.1 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Neur_chan_memb PF02932.16 OWF39062.1 - 0.084 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MMR_HSR1 PF01926.23 OWF39062.1 - 0.12 12.4 0.0 0.49 10.5 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cu2_monoox_C PF03712.15 OWF39062.1 - 0.18 11.3 0.1 0.46 10.0 0.1 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain SbcCD_C PF13558.6 OWF39062.1 - 0.2 11.9 0.2 2.3 8.5 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DSS1_SEM1 PF05160.13 OWF39064.1 - 4.2e-21 74.8 20.6 5.7e-21 74.3 20.6 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 OWF39064.1 - 0.03 14.2 3.9 0.031 14.1 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Thioredoxin PF00085.20 OWF39065.1 - 3.3e-76 251.9 7.5 7e-28 96.6 0.2 4.6 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_2 PF13098.6 OWF39065.1 - 3.3e-16 59.7 1.2 0.00011 22.6 0.0 3.9 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OWF39065.1 - 4.4e-16 58.8 0.3 0.00027 21.1 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.21 OWF39065.1 - 2e-14 53.6 1.3 0.00028 20.8 0.0 4.2 4 0 0 4 4 4 3 AhpC/TSA family Thioredoxin_8 PF13905.6 OWF39065.1 - 1.6e-12 47.6 0.3 0.0077 16.5 0.0 4.7 4 0 0 4 4 4 3 Thioredoxin-like Redoxin PF08534.10 OWF39065.1 - 8.1e-08 32.1 2.8 0.019 14.7 0.0 3.8 4 0 0 4 4 4 2 Redoxin OST3_OST6 PF04756.13 OWF39065.1 - 3.9e-07 29.7 0.0 0.0096 15.3 0.1 2.8 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family TraF PF13728.6 OWF39065.1 - 7.1e-05 22.7 6.3 0.46 10.3 0.1 4.3 3 1 1 4 4 4 2 F plasmid transfer operon protein Glutaredoxin PF00462.24 OWF39065.1 - 0.00012 22.2 4.3 1.7 8.9 0.0 4.0 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin_9 PF14595.6 OWF39065.1 - 0.00021 21.0 0.4 3.4 7.5 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_4 PF13462.6 OWF39065.1 - 0.027 14.6 3.0 5.7 7.1 0.0 3.4 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_6 PF13848.6 OWF39065.1 - 0.035 14.0 2.5 0.87 9.5 0.2 3.5 3 0 0 3 3 3 0 Thioredoxin-like domain DSBA PF01323.20 OWF39065.1 - 0.072 12.9 0.3 28 4.4 0.0 3.3 3 0 0 3 3 3 0 DSBA-like thioredoxin domain Ribosomal_L32p PF01783.23 OWF39066.1 - 4e-05 23.8 2.8 7e-05 23.0 2.8 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Proteasome PF00227.26 OWF39067.1 - 1.8e-60 203.7 0.1 2.8e-60 203.1 0.1 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 OWF39067.1 - 2.8e-10 39.7 0.1 4.9e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.15 OWF39067.1 - 0.04 14.3 0.0 0.63 10.4 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain RRM_1 PF00076.22 OWF39068.1 - 4.8e-17 61.6 0.0 1.1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF39068.1 - 0.0074 16.4 0.1 0.022 14.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Ald_Xan_dh_C2 PF02738.18 OWF39069.1 - 9.1e-179 595.4 0.1 1.3e-178 594.9 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OWF39069.1 - 2e-32 112.3 0.0 3.8e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OWF39069.1 - 6.8e-31 106.1 0.1 4.3e-30 103.5 0.1 2.4 2 0 0 2 2 2 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 OWF39069.1 - 1.4e-30 105.9 0.3 2.6e-30 105.0 0.3 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OWF39069.1 - 5.9e-17 61.7 0.3 2.1e-16 59.9 0.0 2.2 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OWF39069.1 - 1.3e-09 37.8 3.1 1.6e-09 37.6 0.9 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain HTH_24 PF13412.6 OWF39069.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DHODB_Fe-S_bind PF10418.9 OWF39069.1 - 1.7 8.5 12.1 0.2 11.5 4.4 2.8 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B PP2C_2 PF13672.6 OWF39070.1 - 6.3e-08 32.5 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OWF39070.1 - 0.015 15.2 0.1 0.13 12.2 0.0 2.3 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) UBX PF00789.20 OWF39071.1 - 6.8e-16 58.2 0.0 1.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain BTP PF05232.12 OWF39071.1 - 0.065 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Chlorhexidine efflux transporter DUF3584 PF12128.8 OWF39071.1 - 0.07 10.7 26.4 0.091 10.3 26.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMEM52 PF14979.6 OWF39071.1 - 0.14 12.0 0.5 0.37 10.7 0.5 1.7 1 0 0 1 1 1 0 Transmembrane 52 DUF3675 PF12428.8 OWF39073.1 - 0.018 15.6 0.9 0.02 15.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) EF-hand_13 PF17958.1 OWF39073.1 - 0.02 14.7 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain Anoctamin PF04547.12 OWF39073.1 - 0.03 13.2 1.1 0.032 13.1 1.1 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel Ank_2 PF12796.7 OWF39074.1 - 2.2e-16 60.2 0.0 1.1e-10 41.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39074.1 - 3.2e-14 53.1 0.3 9.5e-05 22.9 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39074.1 - 3.9e-11 42.2 0.1 0.056 14.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OWF39074.1 - 1.2e-10 41.3 0.1 0.019 15.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OWF39074.1 - 6.4e-08 32.7 0.3 0.0022 18.3 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF39074.1 - 0.00018 21.8 1.4 0.00018 21.8 1.4 2.3 2 0 0 2 2 2 1 SOCS box Prefoldin PF02996.17 OWF39077.1 - 2.1e-24 85.8 2.7 3e-24 85.2 2.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit ING PF12998.7 OWF39077.1 - 0.0064 17.1 3.2 0.019 15.5 0.9 2.1 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Mst1_SARAH PF11629.8 OWF39077.1 - 0.18 11.9 3.5 6.9 6.8 0.0 2.8 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Sec20 PF03908.13 OWF39077.1 - 0.32 10.9 5.2 4.3 7.3 0.4 2.4 2 0 0 2 2 2 0 Sec20 IFT20 PF14931.6 OWF39077.1 - 0.44 10.7 7.2 2.2 8.4 0.2 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Dynein_IC2 PF11540.8 OWF39078.1 - 7.3e-13 48.2 0.4 1.6e-12 47.2 0.4 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 OWF39078.1 - 7.5e-09 36.1 13.1 0.086 13.8 0.1 7.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF39078.1 - 0.0038 17.5 0.5 23 5.3 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SUKH-4 PF14435.6 OWF39078.1 - 0.16 12.0 3.3 1.5 8.8 0.2 2.8 3 0 0 3 3 3 0 SUKH-4 immunity protein DUF4355 PF14265.6 OWF39078.1 - 6.1 7.1 14.9 1.9 8.7 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Myosin_head PF00063.21 OWF39079.1 - 8.6e-250 830.6 1.6 1.1e-249 830.2 1.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OWF39079.1 - 2.3e-40 138.3 2.7 5e-40 137.2 2.7 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 OWF39079.1 - 0.0025 17.4 33.4 0.078 12.8 0.1 5.3 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_16 PF13191.6 OWF39079.1 - 0.026 14.9 0.0 0.093 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 OWF39079.1 - 0.16 11.5 1.1 23 4.5 0.0 2.8 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain Sgf11 PF08209.11 OWF39080.1 - 1.6e-16 59.5 3.0 2.9e-16 58.7 3.0 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) SCA7 PF08313.12 OWF39080.1 - 9.6e-05 22.2 3.0 0.0003 20.6 3.0 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Ephrin_rec_like PF07699.13 OWF39081.1 - 1.5e-27 95.1 46.5 6.1e-11 41.9 5.3 7.1 4 2 1 5 5 5 3 Putative ephrin-receptor like HYR PF02494.16 OWF39081.1 - 7.5e-22 77.5 4.2 2.9e-15 56.4 0.2 4.8 5 1 0 5 5 5 2 HYR domain TSP_1 PF00090.19 OWF39081.1 - 3.3e-08 33.6 11.2 3.3e-08 33.6 11.2 4.7 4 0 0 4 4 4 1 Thrombospondin type 1 domain Sushi PF00084.20 OWF39081.1 - 1.8e-07 31.7 41.0 1.5e-06 28.7 1.7 6.4 5 0 0 5 5 5 3 Sushi repeat (SCR repeat) DUF2318 PF10080.9 OWF39081.1 - 0.078 13.1 24.1 0.26 11.4 4.2 5.0 2 2 1 3 3 3 0 Predicted membrane protein (DUF2318) Pentaxin PF00354.17 OWF39081.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Pentaxin family EGF PF00008.27 OWF39081.1 - 4.9 7.5 25.8 1.6 9.1 4.2 5.3 4 0 0 4 4 4 0 EGF-like domain SOG2 PF10428.9 OWF39081.1 - 7.5 5.6 25.4 5.4 6.1 23.1 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein DED PF01335.21 OWF39082.1 - 3.8e-14 52.7 0.3 1.1e-13 51.3 0.1 1.7 2 0 0 2 2 2 1 Death effector domain DED PF01335.21 OWF39083.1 - 4.7e-14 52.4 2.2 4.7e-14 52.4 2.2 3.4 3 0 0 3 3 3 1 Death effector domain AAA_14 PF13173.6 OWF39083.1 - 0.00065 19.7 0.4 0.00065 19.7 0.4 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OWF39083.1 - 0.0025 18.1 2.6 0.015 15.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain DED PF01335.21 OWF39084.1 - 5e-16 58.8 1.0 1.7e-15 57.1 1.0 2.0 1 0 0 1 1 1 1 Death effector domain CLLAC PF15675.5 OWF39084.1 - 0.018 14.6 0.6 0.039 13.5 0.6 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain AAA_14 PF13173.6 OWF39084.1 - 0.03 14.4 0.6 0.16 12.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain Solute_trans_a PF03619.16 OWF39085.1 - 8.7e-41 140.2 17.0 1.1e-40 139.9 17.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha EBP PF05241.12 OWF39085.1 - 0.0032 16.9 0.4 0.013 15.0 0.4 2.1 1 1 0 1 1 1 1 Emopamil binding protein DUF572 PF04502.13 OWF39086.1 - 6.9e-76 256.0 13.3 1.3e-75 255.1 13.3 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) hDGE_amylase PF14701.6 OWF39087.1 - 2e-146 488.6 1.8 2.6e-146 488.2 1.8 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OWF39087.1 - 1.4e-124 415.9 0.0 2.2e-124 415.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OWF39087.1 - 1.7e-78 263.8 0.0 3.1e-78 263.0 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OWF39087.1 - 5.8e-22 77.6 0.0 1.3e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OWF39087.1 - 0.049 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Apolipoprotein PF01442.18 OWF39088.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain LMBR1 PF04791.16 OWF39089.1 - 4.5e-177 590.0 14.6 5.2e-177 589.8 14.6 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF948 PF06103.11 OWF39089.1 - 0.13 12.5 0.2 3.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RNA_pol_Rpb4 PF03874.16 OWF39090.1 - 2.7e-25 89.0 2.5 4.1e-25 88.5 2.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 FANC_SAP PF18081.1 OWF39090.1 - 0.066 13.4 0.0 2.8 8.2 0.0 2.3 2 1 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain NDUF_B6 PF09782.9 OWF39091.1 - 4.5e-12 46.4 3.9 1.6e-11 44.6 3.9 1.8 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit XK-related PF09815.9 OWF39092.1 - 1.6e-56 191.9 44.6 2.2e-56 191.4 44.6 1.1 1 0 0 1 1 1 1 XK-related protein Ribosomal_L7Ae PF01248.26 OWF39093.1 - 5.9e-29 99.7 3.3 7.2e-29 99.4 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF333 PF03891.15 OWF39093.1 - 0.054 13.7 0.4 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF333) Sulfotransfer_1 PF00685.27 OWF39095.1 - 4.2e-32 111.7 0.1 5.7e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF39095.1 - 3.8e-12 47.1 0.0 4.4e-08 33.8 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF39095.1 - 0.048 13.6 0.1 0.08 12.8 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF39096.1 - 1e-27 97.3 0.5 1.5e-27 96.8 0.5 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF39096.1 - 1.7e-15 58.0 0.1 3.1e-11 44.1 0.2 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF39096.1 - 0.0011 18.9 0.2 0.0031 17.5 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family FANCI_HD2 PF14680.6 OWF39096.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 FANCI helical domain 2 TPT PF03151.16 OWF39097.1 - 1.4e-15 57.4 15.9 1.7e-15 57.1 15.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OWF39097.1 - 0.00053 20.2 29.6 0.0072 16.5 8.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family Joubert PF15392.6 OWF39098.1 - 3.9e-12 46.6 18.9 3.9e-12 46.6 18.9 8.2 6 3 0 7 7 7 2 Joubert syndrome-associated DUF4936 PF16290.5 OWF39098.1 - 0.059 14.1 0.0 19 6.0 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) CFC PF09443.10 OWF39099.1 - 2e-07 30.7 4.4 2e-07 30.7 4.4 2.1 2 0 0 2 2 2 1 Cripto_Frl-1_Cryptic (CFC) EGF_2 PF07974.13 OWF39099.1 - 0.023 15.1 12.5 0.023 15.1 12.5 2.5 2 0 0 2 2 2 0 EGF-like domain zf-3CxxC PF13695.6 OWF39100.1 - 2e-07 31.4 18.5 4.3e-07 30.3 18.5 1.7 1 1 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 OWF39100.1 - 2.7e-07 31.2 24.1 2.1e-06 28.4 24.1 2.4 1 1 0 1 1 1 1 Zinc-binding domain Neur_chan_LBD PF02931.23 OWF39101.1 - 6e-44 150.1 2.9 8.4e-44 149.6 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF39101.1 - 4.8e-12 46.4 0.8 4.8e-12 46.4 0.8 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Cation_ATPase_C PF00689.21 OWF39101.1 - 0.7 9.6 7.2 0.33 10.7 3.5 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Pigment_DH PF06324.11 OWF39102.1 - 0.057 13.5 0.1 0.057 13.5 0.1 2.4 3 0 0 3 3 3 0 Pigment-dispersing hormone (PDH) Neur_chan_LBD PF02931.23 OWF39103.1 - 6.4e-46 156.5 1.9 8.6e-46 156.1 1.9 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Prion_bPrPp PF11587.8 OWF39103.1 - 0.17 11.8 0.4 25 4.8 0.0 2.5 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal Neur_chan_LBD PF02931.23 OWF39104.1 - 5.4e-46 156.7 1.2 7.8e-46 156.2 1.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF39104.1 - 1.1e-17 65.0 0.6 1.1e-17 65.0 0.6 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF39105.1 - 8.5e-46 156.1 1.1 1.2e-45 155.6 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF39105.1 - 1.1e-17 65.0 0.6 1.1e-17 65.0 0.6 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2 PF00096.26 OWF39106.1 - 0.0035 17.7 1.8 0.55 10.8 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OWF39106.1 - 0.071 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OWF39106.1 - 0.08 13.8 6.7 0.29 12.1 0.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF39106.1 - 0.082 13.4 1.6 0.5 10.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 OWF39106.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type SPX PF03105.19 OWF39106.1 - 0.51 10.2 7.4 0.59 10.0 7.4 1.1 1 0 0 1 1 1 0 SPX domain BTB_2 PF02214.22 OWF39107.1 - 5.7e-16 58.6 0.0 7.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OWF39107.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Neur_chan_LBD PF02931.23 OWF39108.1 - 3.1e-76 255.6 10.5 1e-41 142.8 2.9 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF39108.1 - 3.2e-22 79.8 13.8 1.2e-11 45.1 0.3 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region He_PIG_assoc PF10632.9 OWF39108.1 - 0.17 11.6 0.1 32 4.3 0.0 2.7 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase MnhB PF04039.13 OWF39108.1 - 0.5 10.7 4.3 1.4 9.3 0.3 2.6 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF5419 PF17441.2 OWF39108.1 - 6.5 6.9 6.0 13 6.0 0.2 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5419) Neur_chan_LBD PF02931.23 OWF39109.1 - 6.1e-46 156.6 2.1 1e-45 155.9 2.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF39109.1 - 9.5e-12 45.5 11.6 9.5e-12 45.5 11.6 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Lectin_C PF00059.21 OWF39110.1 - 9.9e-06 26.3 0.0 1.6e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain F5_F8_type_C PF00754.25 OWF39110.1 - 0.00037 20.6 0.2 0.0011 19.1 0.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain F5_F8_type_C PF00754.25 OWF39111.1 - 8e-24 84.2 2.5 1.3e-23 83.5 2.5 1.3 1 0 0 1 1 1 1 F5/8 type C domain Lectin_C PF00059.21 OWF39111.1 - 7.3e-05 23.5 1.9 0.00014 22.5 0.0 2.3 2 1 1 3 3 3 1 Lectin C-type domain Muskelin_N PF06588.11 OWF39111.1 - 0.055 13.4 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Muskelin N-terminus COG5 PF10392.9 OWF39111.1 - 0.093 12.9 2.4 0.84 9.8 0.2 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3787 PF12655.7 OWF39111.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) Neur_chan_LBD PF02931.23 OWF39112.1 - 4.7e-44 150.4 0.7 6.5e-44 149.9 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF39112.1 - 6e-13 49.4 3.3 6e-13 49.4 3.3 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Fringe PF02434.16 OWF39113.1 - 1.5e-11 44.2 2.4 4.8e-11 42.6 2.4 1.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF39113.1 - 1.3e-09 38.2 0.5 2.6e-06 27.4 0.6 2.4 1 1 1 2 2 2 2 Galactosyltransferase Glyco_hydro_38N PF01074.22 OWF39114.1 - 1.5e-101 339.6 1.0 2.3e-101 339.0 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF39114.1 - 2.4e-32 112.8 0.1 8.5e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF39114.1 - 2.8e-16 59.4 0.0 9.4e-16 57.8 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 OWF39114.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 OWF39114.1 - 0.11 12.4 0.3 0.62 10.0 0.1 2.3 2 1 0 2 2 2 0 Polysaccharide deacetylase DivIC PF04977.15 OWF39114.1 - 0.2 11.4 2.3 0.49 10.2 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator SH3_6 PF12913.7 OWF39114.1 - 0.23 11.0 1.2 1.1e+02 2.4 0.0 3.7 3 0 0 3 3 3 0 SH3 domain (SH3b1 type) zf-H2C2_2 PF13465.6 OWF39115.1 - 7.8e-30 102.0 50.6 3.2e-07 30.5 0.4 9.0 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 OWF39115.1 - 4.1e-27 93.1 87.1 9e-05 22.7 1.7 10.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF39115.1 - 6.1e-23 79.5 81.9 0.00055 20.5 1.0 10.0 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF39115.1 - 3.4e-06 27.2 51.5 0.69 10.3 2.1 9.5 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF39115.1 - 4.9e-06 26.7 52.3 0.11 12.9 1.5 9.4 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 OWF39115.1 - 2.6e-05 23.9 0.8 2.6e-05 23.9 0.8 7.9 8 1 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OWF39115.1 - 0.0067 16.4 0.9 0.0067 16.4 0.9 8.8 9 0 0 9 9 9 6 C2H2-type zinc finger BolA PF01722.18 OWF39115.1 - 0.07 13.4 4.9 9.2 6.6 0.1 4.1 2 1 0 3 3 3 0 BolA-like protein zf-C2HC_2 PF13913.6 OWF39115.1 - 0.18 11.7 27.9 0.24 11.4 0.3 6.1 6 0 0 6 6 6 0 zinc-finger of a C2HC-type BACK PF07707.15 OWF39116.1 - 6.1e-09 35.9 0.0 2.7e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 BTB And C-terminal Kelch PHR PF08005.12 OWF39116.1 - 8.4e-05 23.3 0.0 0.0078 16.9 0.0 2.3 2 0 0 2 2 2 1 PHR domain DUF3755 PF12579.8 OWF39116.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) SMC_N PF02463.19 OWF39118.1 - 4.8e-55 186.4 50.7 1.4e-53 181.6 50.7 3.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OWF39118.1 - 7e-19 68.3 0.4 2.5e-18 66.5 0.4 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OWF39118.1 - 1.3e-11 44.9 0.7 0.00016 21.6 0.5 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OWF39118.1 - 1.6e-05 24.8 7.3 1.6e-05 24.8 7.3 5.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 OWF39118.1 - 0.00081 19.1 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4200 PF13863.6 OWF39118.1 - 0.00084 19.7 33.3 0.00084 19.7 33.3 8.1 4 2 3 7 7 7 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 OWF39118.1 - 0.0042 16.0 21.6 0.0042 16.0 21.6 7.0 3 2 4 7 7 7 4 Spc7 kinetochore protein DUF3755 PF12579.8 OWF39119.1 - 1.7e-10 40.3 4.1 1.5 8.5 0.0 6.1 1 1 7 8 8 8 0 Protein of unknown function (DUF3755) Synaptobrevin PF00957.21 OWF39119.1 - 2.8e-06 27.0 18.0 0.072 12.9 3.3 4.0 1 1 4 5 5 5 4 Synaptobrevin Phasin_2 PF09361.10 OWF39119.1 - 2.9e-06 27.5 4.8 6e-06 26.5 4.8 1.5 1 1 0 1 1 1 1 Phasin protein DUF148 PF02520.17 OWF39119.1 - 4.5e-06 26.7 13.3 0.0052 16.9 6.1 2.2 1 1 1 2 2 2 2 Domain of unknown function DUF148 Apolipoprotein PF01442.18 OWF39119.1 - 5e-06 26.5 1.9 5.9e-06 26.3 1.9 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OWF39119.1 - 6.5e-06 26.3 13.5 7.7e-06 26.1 13.5 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 OWF39119.1 - 9e-06 25.8 7.1 5.2e-05 23.3 7.1 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Exo70 PF03081.15 OWF39119.1 - 2.5e-05 23.5 4.8 0.01 14.9 1.1 2.0 1 1 1 2 2 2 2 Exo70 exocyst complex subunit YtxH PF12732.7 OWF39119.1 - 0.00017 22.1 9.9 0.95 10.0 9.9 2.2 1 1 0 1 1 1 1 YtxH-like protein MT0933_antitox PF14013.6 OWF39119.1 - 0.00019 21.7 2.4 0.31 11.4 0.3 2.7 1 1 1 2 2 2 2 MT0933-like antitoxin protein Tape_meas_lam_C PF09718.10 OWF39119.1 - 0.00022 21.3 2.5 0.32 11.2 0.3 2.4 1 1 1 2 2 2 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RmuC PF02646.16 OWF39119.1 - 0.00058 19.1 15.7 0.0078 15.4 3.7 2.0 1 1 1 2 2 2 2 RmuC family Senescence PF06911.12 OWF39119.1 - 0.00061 20.2 3.8 0.0012 19.2 3.7 1.6 1 1 0 1 1 1 1 Senescence-associated protein Phasin PF05597.11 OWF39119.1 - 0.00068 19.6 8.6 0.039 13.9 2.2 2.0 1 1 1 2 2 2 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.10 OWF39119.1 - 0.00074 19.7 13.0 0.0019 18.4 13.0 1.5 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1631 PF07793.11 OWF39119.1 - 0.00081 17.9 0.3 0.47 8.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1631) Nod1 PF17114.5 OWF39119.1 - 0.00092 19.4 9.9 0.095 12.8 3.5 2.1 1 1 1 2 2 2 2 Gef2-related medial cortical node protein Nod1 YojJ PF10372.9 OWF39119.1 - 0.00097 19.2 6.3 0.31 11.2 0.6 2.3 1 1 1 2 2 2 2 Bacterial membrane-spanning protein N-terminus Beta-TrCP_D PF12125.8 OWF39119.1 - 0.0011 18.8 15.0 70 3.4 0.0 7.4 1 1 7 8 8 8 0 D domain of beta-TrCP POTRA_TamA_1 PF17243.2 OWF39119.1 - 0.0011 19.0 1.2 0.57 10.3 1.2 3.2 1 1 0 1 1 1 1 POTRA domain TamA domain 1 Octopine_DH PF02317.17 OWF39119.1 - 0.0011 19.1 0.1 0.056 13.5 0.1 2.3 1 1 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF883 PF05957.13 OWF39119.1 - 0.0012 19.4 1.9 0.0041 17.7 1.9 1.8 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) DUF4795 PF16043.5 OWF39119.1 - 0.0012 18.5 9.7 0.0017 18.0 9.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Prominin PF05478.11 OWF39119.1 - 0.0013 16.8 11.8 0.0014 16.7 11.8 1.0 1 0 0 1 1 1 1 Prominin Cor1 PF04803.12 OWF39119.1 - 0.0013 18.9 11.8 0.046 13.9 3.6 2.0 1 1 1 2 2 2 2 Cor1/Xlr/Xmr conserved region DUF4202 PF13875.6 OWF39119.1 - 0.0018 18.2 4.5 2.4 8.0 4.5 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4202) AAA_lid_10 PF17872.1 OWF39119.1 - 0.0018 18.4 9.8 0.52 10.5 2.1 2.9 1 1 1 2 2 2 2 AAA lid domain DUF2884 PF11101.8 OWF39119.1 - 0.0019 17.7 7.5 0.0026 17.3 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Collagen_mid PF15984.5 OWF39119.1 - 0.0028 17.5 1.6 0.0038 17.0 1.6 1.2 1 0 0 1 1 1 1 Bacterial collagen, middle region CorA PF01544.18 OWF39119.1 - 0.0029 17.0 8.4 0.037 13.4 3.7 2.0 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein DUF1043 PF06295.12 OWF39119.1 - 0.0032 17.4 6.3 0.39 10.7 2.8 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1043) RXLR_WY PF18634.1 OWF39119.1 - 0.0033 17.3 14.3 20 5.2 0.1 6.0 1 1 6 7 7 7 0 RXLR phytopathogen effector protein WY-domain DUF445 PF04286.12 OWF39119.1 - 0.0047 16.8 5.2 0.0056 16.5 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Dpoe2NT PF12213.8 OWF39119.1 - 0.0054 17.0 7.2 20 5.6 0.3 4.1 1 1 4 5 5 5 0 DNA polymerases epsilon N terminal GlutR_dimer PF00745.20 OWF39119.1 - 0.006 17.0 1.5 0.48 10.9 0.2 2.0 1 1 1 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain CDC37_C PF08564.10 OWF39119.1 - 0.0061 16.7 20.2 5 7.3 2.7 5.9 1 1 4 5 5 5 0 Cdc37 C terminal domain IFT57 PF10498.9 OWF39119.1 - 0.0063 15.5 8.9 0.0078 15.2 8.9 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 SieB PF14163.6 OWF39119.1 - 0.0066 15.9 3.8 0.56 9.7 3.8 2.3 1 1 0 1 1 1 1 Super-infection exclusion protein B DUF4473 PF14747.6 OWF39119.1 - 0.0077 16.8 3.6 1.1 9.9 1.3 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4473) PhageMin_Tail PF10145.9 OWF39119.1 - 0.0079 16.1 9.7 0.076 12.9 9.7 2.0 1 1 0 1 1 1 1 Phage-related minor tail protein DUF948 PF06103.11 OWF39119.1 - 0.0085 16.3 10.3 0.73 10.1 10.3 2.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Carbpep_Y_N PF05388.11 OWF39119.1 - 0.0085 16.6 9.4 0.032 14.8 9.4 1.8 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide ApoO PF09769.9 OWF39119.1 - 0.0091 16.0 2.2 0.61 10.1 2.2 2.2 1 1 0 1 1 1 1 Apolipoprotein O BshC PF10079.9 OWF39119.1 - 0.0093 14.8 6.7 0.01 14.6 6.7 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Sec3_C PF09763.9 OWF39119.1 - 0.01 14.3 10.7 0.063 11.7 10.7 1.9 1 1 0 1 1 1 0 Exocyst complex component Sec3 ACP_PD PF04336.12 OWF39119.1 - 0.01 16.2 0.4 0.065 13.7 0.4 2.2 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase EntA_Immun PF08951.10 OWF39119.1 - 0.011 16.1 9.5 8.8 6.8 0.4 4.1 1 1 3 4 4 4 0 Enterocin A Immunity IL32 PF15225.6 OWF39119.1 - 0.011 16.0 0.4 1.7 9.0 0.1 2.0 1 1 1 2 2 2 0 Interleukin 32 DUF5327 PF17261.2 OWF39119.1 - 0.011 16.4 14.7 7.5 7.4 1.9 4.3 1 1 2 3 3 3 0 Family of unknown function (DUF5327) DHC_N2 PF08393.13 OWF39119.1 - 0.012 14.8 5.9 0.024 13.8 6.0 1.5 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF4946 PF16304.5 OWF39119.1 - 0.016 14.9 16.3 4.9 6.8 0.9 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4946) FliG_N PF14842.6 OWF39119.1 - 0.016 15.7 3.5 0.033 14.7 3.5 1.6 1 1 0 1 1 1 0 FliG N-terminal domain UBA_6 PF18039.1 OWF39119.1 - 0.017 15.1 13.7 30 4.6 0.9 6.2 1 1 3 4 4 4 0 UBA-like domain RHD3 PF05879.12 OWF39119.1 - 0.017 13.3 7.2 0.019 13.1 7.2 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Cucumopine_C PF18631.1 OWF39119.1 - 0.018 15.0 0.4 43 4.0 0.0 3.0 1 1 2 4 4 4 0 Cucumopine synthase C-terminal helical bundle domain DUF1451 PF07295.11 OWF39119.1 - 0.018 15.1 4.0 0.022 14.8 4.0 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Sec5 PF15469.6 OWF39119.1 - 0.019 14.8 9.6 0.2 11.4 9.6 2.0 1 1 0 1 1 1 0 Exocyst complex component Sec5 DUF1804 PF08822.11 OWF39119.1 - 0.019 14.9 5.6 0.033 14.2 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1804) Tektin PF03148.14 OWF39119.1 - 0.019 13.7 4.9 0.055 12.2 4.9 1.6 1 1 0 1 1 1 0 Tektin family AbiJ_NTD5 PF18865.1 OWF39119.1 - 0.02 14.7 5.2 3.6 7.4 2.0 2.8 1 1 1 2 2 2 0 AbiJ N-terminal domain 5 PIN_8 PF18476.1 OWF39119.1 - 0.021 14.7 5.4 0.024 14.5 5.4 1.1 1 0 0 1 1 1 0 PIN like domain DUF4456 PF14644.6 OWF39119.1 - 0.022 14.5 4.7 0.025 14.2 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Pneumo_M2 PF07380.11 OWF39119.1 - 0.024 14.9 0.2 3.9 7.8 0.1 2.3 1 1 1 2 2 2 0 Pneumovirus M2 protein DUF1664 PF07889.12 OWF39119.1 - 0.024 14.7 14.2 0.051 13.6 14.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GIT1_C PF12205.8 OWF39119.1 - 0.024 14.7 5.3 0.07 13.2 5.3 1.7 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4413 PF14372.6 OWF39119.1 - 0.025 14.9 10.7 23 5.4 10.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) DUF1708 PF08101.11 OWF39119.1 - 0.027 13.6 8.1 0.31 10.1 8.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1708) DUF3677 PF12432.8 OWF39119.1 - 0.028 14.7 7.7 0.78 10.1 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3677) CHDCT2 PF08074.11 OWF39119.1 - 0.029 14.6 10.2 2.8 8.1 10.2 2.3 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain SKA2 PF16740.5 OWF39119.1 - 0.031 14.1 7.7 0.043 13.6 7.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 GT-D PF08759.11 OWF39119.1 - 0.035 13.8 3.2 0.043 13.5 3.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Gp_UL130 PF11668.8 OWF39119.1 - 0.037 14.0 2.0 2.8 7.8 0.3 2.1 1 1 1 2 2 2 0 HCMV glycoprotein pUL130 Herpes_BBRF1 PF04793.12 OWF39119.1 - 0.037 13.1 3.1 0.14 11.1 3.1 1.8 1 1 0 1 1 1 0 BRRF1-like protein Vps51 PF08700.11 OWF39119.1 - 0.037 14.1 13.1 4.2 7.5 1.0 3.5 1 1 1 2 2 2 0 Vps51/Vps67 Tweety PF04906.13 OWF39119.1 - 0.038 12.7 6.9 0.057 12.1 6.9 1.3 1 0 0 1 1 1 0 Tweety FANCI_S2 PF14676.6 OWF39119.1 - 0.039 14.3 4.0 0.058 13.7 4.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 2 Gp-FAR-1 PF05823.12 OWF39119.1 - 0.039 14.3 7.9 0.042 14.2 7.9 1.1 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) AI-2E_transport PF01594.16 OWF39119.1 - 0.043 13.0 2.4 0.094 11.9 2.4 1.6 1 1 0 1 1 1 0 AI-2E family transporter HU-HIG PF18291.1 OWF39119.1 - 0.043 13.9 5.0 4.1 7.5 0.5 2.2 1 1 1 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif REF PF05755.12 OWF39119.1 - 0.046 13.5 6.5 0.075 12.8 6.5 1.4 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) CdvA PF18822.1 OWF39119.1 - 0.049 13.5 6.6 1.1 9.0 1.2 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Dynamin_M PF01031.20 OWF39119.1 - 0.051 12.8 6.2 0.13 11.5 6.2 1.6 1 1 0 1 1 1 0 Dynamin central region SseC PF04888.12 OWF39119.1 - 0.051 13.2 16.3 2.8 7.5 7.2 2.4 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Vac14_Fab1_bd PF12755.7 OWF39119.1 - 0.054 14.1 3.6 0.24 12.0 3.6 1.9 1 1 0 1 1 1 0 Vacuolar 14 Fab1-binding region DUF4618 PF15397.6 OWF39119.1 - 0.055 12.9 11.0 0.083 12.3 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Agglutinin PF07468.11 OWF39119.1 - 0.056 13.6 7.2 11 6.3 0.3 3.2 1 1 3 4 4 4 0 Agglutinin domain DUF2205 PF10224.9 OWF39119.1 - 0.059 13.4 7.3 2.1 8.4 1.3 2.5 1 1 1 2 2 2 0 Short coiled-coil protein DUF3445 PF11927.8 OWF39119.1 - 0.059 13.0 2.4 5.7 6.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3445) Exonuc_VII_L PF02601.15 OWF39119.1 - 0.061 12.9 5.6 0.069 12.7 5.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit LXG PF04740.12 OWF39119.1 - 0.062 13.0 12.3 0.44 10.2 6.1 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF4735 PF15882.5 OWF39119.1 - 0.062 12.7 3.7 0.077 12.4 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) DXP_synthase_N PF13292.6 OWF39119.1 - 0.062 12.5 6.5 0.7 9.0 6.5 1.9 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase FlaC_arch PF05377.11 OWF39119.1 - 0.064 13.7 21.6 9.4 6.7 5.4 4.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) ERp29 PF07749.12 OWF39119.1 - 0.066 14.1 4.4 0.19 12.6 4.4 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain p450 PF00067.22 OWF39119.1 - 0.07 11.9 4.2 0.076 11.7 4.2 1.0 1 0 0 1 1 1 0 Cytochrome P450 3H PF02829.14 OWF39119.1 - 0.073 13.4 5.0 9.2 6.6 0.5 2.8 1 1 2 3 3 3 0 3H domain Cupin_4 PF08007.12 OWF39119.1 - 0.077 12.4 2.6 0.092 12.2 2.6 1.2 1 0 0 1 1 1 0 Cupin superfamily protein DUF2130 PF09903.9 OWF39119.1 - 0.078 12.2 7.3 0.38 10.0 7.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) KxDL PF10241.9 OWF39119.1 - 0.079 13.2 9.1 2 8.8 9.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein RGP PF03214.13 OWF39119.1 - 0.082 12.0 3.0 4.2 6.4 0.2 1.9 1 1 1 2 2 2 0 Reversibly glycosylated polypeptide AAA_32 PF13654.6 OWF39119.1 - 0.086 11.6 4.3 0.098 11.4 4.3 1.1 1 0 0 1 1 1 0 AAA domain zf-DNA_Pol PF08996.10 OWF39119.1 - 0.087 12.6 8.0 1.6 8.5 1.8 2.0 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger FliG_M PF14841.6 OWF39119.1 - 0.098 12.9 4.1 3.1 8.1 0.8 2.6 1 1 1 2 2 2 0 FliG middle domain DUF2523 PF10734.9 OWF39119.1 - 0.1 13.2 3.8 30 5.3 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2523) Asp23 PF03780.13 OWF39119.1 - 0.11 13.0 9.4 18 5.8 0.4 3.5 1 1 2 3 3 3 0 Asp23 family, cell envelope-related function Borealin PF10512.9 OWF39119.1 - 0.11 12.5 11.8 2.3 8.2 2.6 2.6 1 1 3 4 4 4 0 Cell division cycle-associated protein 8 ArsA_ATPase PF02374.15 OWF39119.1 - 0.12 11.5 8.3 0.67 9.1 8.3 1.9 1 1 0 1 1 1 0 Anion-transporting ATPase EspB PF05802.11 OWF39119.1 - 0.12 12.3 8.1 0.29 11.1 8.1 1.7 1 1 0 1 1 1 0 Enterobacterial EspB protein CPG4 PF15481.6 OWF39119.1 - 0.13 12.9 2.0 0.19 12.4 2.0 1.3 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 Peptidase_M41 PF01434.18 OWF39119.1 - 0.14 12.0 6.3 0.3 10.9 6.3 1.6 1 1 0 1 1 1 0 Peptidase family M41 DLP_helical PF18709.1 OWF39119.1 - 0.14 11.3 7.7 1.4 8.1 2.2 1.7 1 1 1 2 2 2 0 Dynamin-like helical domain HSBP1 PF06825.12 OWF39119.1 - 0.15 12.0 19.9 1.8e+04 -6.4 19.9 4.7 1 1 0 1 1 0 0 Heat shock factor binding protein 1 DUF842 PF05811.13 OWF39119.1 - 0.15 11.8 7.9 0.23 11.1 7.9 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) EcsC PF12787.7 OWF39119.1 - 0.15 11.7 3.1 0.33 10.6 3.1 1.6 1 1 0 1 1 1 0 EcsC protein family DUF1759 PF03564.15 OWF39119.1 - 0.17 11.8 4.8 0.48 10.3 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) Allexi_40kDa PF05549.11 OWF39119.1 - 0.17 11.3 7.3 0.19 11.2 7.3 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein TIP120 PF08623.10 OWF39119.1 - 0.18 11.6 7.7 0.39 10.5 7.7 1.6 1 1 0 1 1 1 0 TATA-binding protein interacting (TIP20) Corona_S2 PF01601.16 OWF39119.1 - 0.18 10.2 8.7 0.24 9.8 8.7 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BMFP PF04380.13 OWF39119.1 - 0.2 12.2 5.1 10 6.7 5.1 2.5 1 1 0 1 1 1 0 Membrane fusogenic activity Latarcin PF10279.9 OWF39119.1 - 0.26 11.7 8.5 2.3e+02 2.3 8.5 3.2 1 1 0 1 1 1 0 Latarcin precursor ALMT PF11744.8 OWF39119.1 - 0.27 10.0 10.6 0.6 8.9 10.6 1.6 1 1 0 1 1 1 0 Aluminium activated malate transporter Muted PF14942.6 OWF39119.1 - 0.27 11.6 9.8 0.56 10.5 9.8 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein STI1 PF17830.1 OWF39119.1 - 0.28 11.1 17.8 5.5 7.0 1.9 3.4 1 1 4 5 5 5 0 STI1 domain Cnd1_N PF12922.7 OWF39119.1 - 0.28 11.0 10.1 3.9 7.3 1.5 2.5 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF2408 PF10303.9 OWF39119.1 - 0.29 11.7 6.0 0.39 11.3 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) RNase_J_C PF17770.1 OWF39119.1 - 0.29 12.2 4.7 6.4 7.9 1.2 2.2 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain PBECR1 PF18809.1 OWF39119.1 - 0.34 11.6 4.0 3.3 8.4 4.0 2.0 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Sun2_CC2 PF18580.1 OWF39119.1 - 0.35 11.1 3.8 25 5.2 0.4 3.0 1 1 3 4 4 4 0 SUN2 coiled coil domain 2 ZYG-11_interact PF05884.12 OWF39119.1 - 0.37 10.2 5.9 0.44 9.9 5.9 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 TMPIT PF07851.13 OWF39119.1 - 0.45 9.7 7.8 0.56 9.4 7.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Pik1 PF11522.8 OWF39119.1 - 0.45 10.5 9.2 12 5.9 1.7 3.1 1 1 1 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 RIG-I_C PF18119.1 OWF39119.1 - 0.48 10.4 8.4 1.9 8.5 1.4 2.0 1 1 1 2 2 2 0 RIG-I receptor C-terminal domain Radial_spoke PF04712.12 OWF39119.1 - 0.51 9.2 9.4 4.7 6.0 9.4 1.9 1 1 0 1 1 1 0 Radial spokehead-like protein His_kinase PF06580.13 OWF39119.1 - 0.65 10.4 3.5 26 5.2 3.5 2.4 1 1 0 1 1 1 0 Histidine kinase DBINO PF13892.6 OWF39119.1 - 0.66 10.3 6.0 2.8 8.3 6.0 1.8 1 1 0 1 1 1 0 DNA-binding domain DUF2228 PF10228.9 OWF39119.1 - 0.7 9.6 6.5 1 9.0 6.5 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Oleosin PF01277.17 OWF39119.1 - 0.77 9.5 2.7 15 5.3 0.4 2.1 1 1 1 2 2 2 0 Oleosin DUF520 PF04461.13 OWF39119.1 - 0.93 9.6 14.1 2.9 8.0 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF520) Fzo_mitofusin PF04799.13 OWF39119.1 - 1.2 8.7 9.9 2.9 7.4 9.9 1.6 1 1 0 1 1 1 0 fzo-like conserved region CENP-Q PF13094.6 OWF39119.1 - 1.3 9.2 9.7 2.9 8.1 9.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NCD2 PF04905.13 OWF39119.1 - 1.9 8.5 9.8 5.2 7.0 2.1 2.0 1 1 1 2 2 2 0 NAB conserved region 2 (NCD2) DUF4535 PF15054.6 OWF39119.1 - 2.4 8.0 8.4 2.7e+03 -1.8 8.4 3.8 1 1 0 1 1 0 0 Domain of unknown function (DUF4535) V-ATPase_G PF03179.15 OWF39119.1 - 2.7 8.6 8.2 50 4.5 8.2 2.1 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Anthrax_toxA PF03497.16 OWF39119.1 - 3.4 7.7 13.1 14 5.7 2.6 2.8 1 1 2 3 3 3 0 Anthrax toxin LF subunit Tugs PF17840.1 OWF39119.1 - 3.5 7.9 7.8 76 3.6 0.4 3.5 1 1 3 4 4 4 0 Tethering Ubl4a to BAGS domain DUF5301 PF17225.3 OWF39119.1 - 5.1 7.6 8.1 17 5.9 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) DUF4787 PF16029.5 OWF39120.1 - 5.9e-23 80.7 6.5 8.4e-23 80.2 6.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) Pkinase_Tyr PF07714.17 OWF39121.1 - 5.4e-41 140.6 0.7 1.7e-35 122.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OWF39121.1 - 5.7e-25 88.2 0.0 1.2e-24 87.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF39121.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Adeno_E3_CR2 PF02439.15 OWF39121.1 - 0.26 11.1 2.7 0.59 9.9 2.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EB1 PF03271.17 OWF39122.1 - 1.9e-16 60.0 1.4 3.4e-16 59.2 0.7 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 OWF39122.1 - 2.9e-13 49.9 1.2 4.4e-13 49.4 0.2 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Proteasome PF00227.26 OWF39123.1 - 8.3e-44 149.3 0.0 1.1e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RTC PF01137.21 OWF39124.1 - 3.1e-59 199.9 0.0 3.6e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 OWF39124.1 - 3.6e-34 117.4 0.0 5.6e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Metallophos PF00149.28 OWF39125.1 - 9.5e-13 49.1 7.6 9.5e-13 49.1 7.6 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Peptidase_M16_M PF16187.5 OWF39127.1 - 4e-79 265.8 0.0 7.4e-79 264.9 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OWF39127.1 - 1.5e-37 128.9 0.0 3.1e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OWF39127.1 - 1e-30 107.1 0.8 4.4e-18 66.0 0.1 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Cwf_Cwc_15 PF04889.12 OWF39127.1 - 0.5 10.1 2.9 0.91 9.2 2.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Alg14 PF08660.11 OWF39128.1 - 7.8e-64 214.8 0.0 9.9e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like 7tm_1 PF00001.21 OWF39129.1 - 9.6e-60 202.1 8.2 1.3e-59 201.7 8.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF39129.1 - 8.6e-12 45.0 4.5 1.8e-11 43.9 4.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF39129.1 - 4.8e-05 23.1 9.2 4.8e-05 23.1 9.2 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF39129.1 - 7.5e-05 22.6 3.0 7.5e-05 22.6 3.0 1.6 2 0 0 2 2 2 1 Olfactory receptor Fibrinogen_C PF00147.18 OWF39130.1 - 1.3e-68 231.1 10.0 1.7e-68 230.7 10.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain BLOC1_2 PF10046.9 OWF39130.1 - 0.0027 18.0 2.0 0.0027 18.0 2.0 2.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF148 PF02520.17 OWF39130.1 - 0.0089 16.1 0.6 0.021 14.9 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF148 DASH_Dad2 PF08654.10 OWF39130.1 - 0.021 15.2 3.2 0.046 14.1 0.9 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 NPR3 PF03666.13 OWF39130.1 - 0.039 12.8 0.1 0.059 12.2 0.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GPR15L PF15854.5 OWF39130.1 - 0.051 13.8 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Spc7 PF08317.11 OWF39130.1 - 0.1 11.5 1.7 0.14 11.0 1.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 OWF39130.1 - 0.16 11.4 1.8 0.25 10.8 1.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein ATF7IP_BD PF16788.5 OWF39130.1 - 0.17 12.0 4.4 0.25 11.4 4.4 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain HypD PF01924.16 OWF39131.1 - 0.033 13.3 1.5 0.057 12.5 1.5 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family Asp_protease_2 PF13650.6 OWF39131.1 - 0.035 14.7 0.0 0.088 13.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 OWF39131.1 - 0.055 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Steroid_dh PF02544.16 OWF39131.1 - 0.055 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase SpoIISA_toxin PF14171.6 OWF39131.1 - 0.079 12.7 2.1 0.12 12.0 2.1 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Retrotrans_gag PF03732.17 OWF39131.1 - 0.15 12.3 4.6 5.1 7.4 1.3 2.7 1 1 1 2 2 2 0 Retrotransposon gag protein 7tm_1 PF00001.21 OWF39133.1 - 1.7e-12 47.2 21.2 2.2e-12 46.9 21.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF39133.1 - 0.0052 16.5 14.5 0.0052 16.5 14.5 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Glyoxalase PF00903.25 OWF39134.1 - 1.5e-24 86.6 2.3 6.7e-17 61.9 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OWF39134.1 - 8.1e-16 58.3 0.3 3.8e-09 36.8 0.2 2.6 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OWF39134.1 - 3.8e-10 40.2 0.1 7.1e-05 23.0 0.1 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 OWF39134.1 - 4.3e-07 30.2 0.1 1.1e-06 28.9 0.1 1.6 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_6 PF18029.1 OWF39134.1 - 0.0072 17.1 0.2 0.046 14.5 0.1 2.2 2 1 0 2 2 2 1 Glyoxalase-like domain FliG_C PF01706.16 OWF39134.1 - 0.11 12.7 0.1 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 FliG C-terminal domain Adeno_E3B PF03376.14 OWF39135.1 - 0.093 13.0 0.6 0.11 12.8 0.6 1.2 1 0 0 1 1 1 0 Adenovirus E3B protein 7tm_1 PF00001.21 OWF39136.1 - 1e-44 152.9 21.5 1.3e-44 152.5 21.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF39136.1 - 4.5e-10 39.6 20.4 6.4e-10 39.1 20.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF39136.1 - 6.7e-10 38.8 17.8 1.1e-09 38.0 17.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RRM_1 PF00076.22 OWF39137.1 - 1.4e-31 108.1 0.1 1e-14 54.1 0.2 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 OWF39137.1 - 4.5e-08 32.3 1.9 1.3e-07 30.9 1.9 1.9 1 0 0 1 1 1 1 Lsm interaction motif LSM_int_assoc PF16605.5 OWF39137.1 - 0.00015 21.8 1.2 0.00042 20.4 1.2 1.8 1 0 0 1 1 1 1 LSM-interacting associated unstructured RRM_occluded PF16842.5 OWF39137.1 - 0.0045 16.8 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OWF39137.1 - 0.075 13.0 0.3 4.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OWF39137.1 - 0.14 12.3 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Herpes_UL17 PF04559.12 OWF39137.1 - 0.63 8.8 5.3 1 8.0 5.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein TPR_14 PF13428.6 OWF39137.1 - 1.3 10.0 7.9 56 5.0 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat ACOX PF01756.19 OWF39138.1 - 7.9e-51 172.2 0.0 1.2e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OWF39138.1 - 2.4e-16 59.7 0.0 4.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OWF39138.1 - 0.0044 17.2 0.0 4.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain CUE PF02845.16 OWF39139.1 - 3.9e-11 42.4 0.1 7.3e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 OWF39139.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif MRP-S23 PF10484.9 OWF39140.1 - 1.8e-38 131.7 0.1 2.7e-38 131.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 OWF39140.1 - 0.0018 17.9 0.6 0.054 13.1 0.1 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 Sugar_tr PF00083.24 OWF39141.1 - 1.1e-35 123.4 28.6 4e-27 95.2 9.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF39141.1 - 9.5e-32 110.3 31.6 1.1e-20 73.9 16.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF39141.1 - 0.005 15.7 10.9 0.026 13.4 0.1 2.6 2 1 0 2 2 2 2 MFS_1 like family UQ_con PF00179.26 OWF39142.1 - 1.1e-49 167.6 0.0 1.3e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF39142.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Leu_zip PF15294.6 OWF39143.1 - 8.6 5.8 62.5 7.5 6.0 21.3 4.2 2 2 1 3 3 3 0 Leucine zipper COR PF16095.5 OWF39144.1 - 1.6e-10 41.1 0.7 5.8e-10 39.3 0.2 2.0 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF39144.1 - 4.3e-08 33.4 0.0 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF39144.1 - 4.8e-08 33.1 0.0 5.1e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Death domain Ras PF00071.22 OWF39144.1 - 0.007 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_12 PF13087.6 OWF39144.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Syndecan PF01034.20 OWF39145.1 - 0.0056 16.6 1.9 0.012 15.6 1.9 1.5 1 0 0 1 1 1 1 Syndecan domain RhoGEF PF00621.20 OWF39149.1 - 2.3e-34 119.2 2.3 1e-33 117.1 1.4 2.5 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 OWF39149.1 - 9.1e-21 73.8 6.1 1.9e-20 72.8 6.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 OWF39149.1 - 2.3e-13 50.5 1.8 9e-08 32.6 0.0 3.1 3 0 0 3 3 3 2 PH domain IQ_SEC7_PH PF16453.5 OWF39149.1 - 1.4e-05 25.0 0.2 4.5e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF39149.1 - 0.00035 20.9 6.4 0.018 15.5 0.3 3.9 3 0 0 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 OWF39149.1 - 0.0016 18.2 2.3 0.52 10.1 2.3 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain FYVE_2 PF02318.16 OWF39149.1 - 0.09 13.0 8.1 0.023 14.9 4.0 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_2 PF13639.6 OWF39149.1 - 0.99 9.8 8.4 2.4 8.5 8.4 1.7 1 0 0 1 1 1 0 Ring finger domain SID-1_RNA_chan PF13965.6 OWF39150.1 - 0.21 10.0 0.8 0.32 9.4 0.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Colicin_Ia PF11504.8 OWF39151.1 - 0.021 15.0 22.4 15 5.8 0.1 9.6 1 1 11 13 13 13 0 Colicin Ia DDR PF08841.10 OWF39151.1 - 0.022 13.7 6.6 2.1 7.2 0.1 4.0 3 1 1 5 5 5 0 Diol dehydratase reactivase ATPase-like domain Corona_NSP4_C PF16348.5 OWF39151.1 - 0.11 13.3 0.0 2.3e+02 2.7 0.0 4.7 3 3 4 7 7 7 0 Coronavirus nonstructural protein 4 C-terminus DUF5472 PF17566.2 OWF39151.1 - 0.58 10.2 47.6 28 4.8 0.3 12.0 1 1 14 15 15 15 0 Family of unknown function (DUF5472) ICMT PF04140.14 OWF39151.1 - 1.8 9.0 6.3 1.4 9.4 1.4 2.4 1 1 1 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4264 PF14084.6 OWF39151.1 - 5.7 6.7 11.4 41 3.9 0.1 5.5 4 2 3 7 7 7 0 Protein of unknown function (DUF4264) TMEM51 PF15345.6 OWF39152.1 - 0.0035 17.2 1.3 0.056 13.3 1.3 2.3 1 1 0 1 1 1 1 Transmembrane protein 51 zf-TAZ PF02135.16 OWF39152.1 - 0.14 12.6 4.2 0.35 11.4 4.2 1.6 1 0 0 1 1 1 0 TAZ zinc finger Adeno_E3_CR2 PF02439.15 OWF39152.1 - 0.14 11.9 3.5 0.49 10.2 3.5 1.9 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HLH PF00010.26 OWF39153.1 - 3.7e-13 49.2 0.6 8e-13 48.1 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UvrB PF12344.8 OWF39153.1 - 0.5 10.2 10.1 0.61 10.0 0.1 2.8 3 0 0 3 3 3 0 Ultra-violet resistance protein B PX PF00787.24 OWF39154.1 - 2.9e-28 98.1 0.0 3.7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 PX domain AFG1_ATPase PF03969.16 OWF39155.1 - 1.9e-109 365.9 0.0 1.5e-105 353.0 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OWF39155.1 - 8.7e-05 23.0 0.2 0.0053 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OWF39155.1 - 0.0022 18.3 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OWF39155.1 - 0.011 16.2 0.0 0.054 13.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 OWF39155.1 - 0.02 14.7 2.8 1.8 8.4 0.1 3.4 4 0 0 4 4 4 0 Bacterial dnaA protein Mrx7 PF10906.8 OWF39155.1 - 0.038 14.2 0.5 0.17 12.1 0.5 2.1 1 0 0 1 1 1 0 MIOREX complex component 7 NACHT PF05729.12 OWF39155.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 OWF39155.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 OWF39155.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CSTF2_hinge PF14327.6 OWF39156.1 - 8.1e-30 103.1 5.1 8.1e-30 103.1 5.1 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OWF39156.1 - 5.1e-25 87.1 0.0 8.1e-25 86.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OWF39156.1 - 3.3e-19 68.2 13.7 8.5e-19 66.9 10.9 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 OWF39156.1 - 0.0043 16.9 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OWF39156.1 - 0.034 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif PHM7_cyt PF14703.6 OWF39156.1 - 0.15 12.3 0.1 3.9 7.7 0.0 2.5 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter C1q PF00386.21 OWF39157.1 - 1e-24 87.1 0.3 2.2e-24 86.1 0.3 1.6 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF39157.1 - 0.00018 21.4 1.3 0.00038 20.4 1.3 1.5 1 0 0 1 1 1 1 BclA C-terminal domain WEMBL PF05701.11 OWF39157.1 - 0.0015 17.4 3.8 0.0021 16.9 3.8 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light MscS_porin PF12795.7 OWF39157.1 - 0.0059 16.2 6.3 0.0059 16.2 6.3 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain FPP PF05911.11 OWF39157.1 - 0.046 11.9 6.0 0.066 11.4 6.0 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CCDC144C PF14915.6 OWF39157.1 - 0.078 12.1 7.4 0.13 11.3 7.4 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Glyco_hydro_32C PF08244.12 OWF39157.1 - 0.093 12.7 2.6 0.12 12.4 1.5 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal OEP PF02321.18 OWF39157.1 - 0.3 10.9 5.1 0.49 10.2 5.1 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein Atg14 PF10186.9 OWF39157.1 - 1.1 8.3 7.1 0.48 9.5 4.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 OWF39157.1 - 3.4 8.3 14.9 0.25 12.0 2.4 2.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 OWF39157.1 - 8 6.6 14.3 0.73 10.0 8.9 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TSNAXIP1_N PF15739.5 OWF39158.1 - 1.8e-23 83.0 2.8 1.8e-23 83.0 2.8 2.6 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Tropomyosin PF00261.20 OWF39158.1 - 0.4 10.0 26.1 19 4.5 0.4 3.2 2 1 0 2 2 2 0 Tropomyosin FAM184 PF15665.5 OWF39158.1 - 5.4 6.7 23.2 1.4 8.7 4.0 2.8 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Vir_act_alpha_C PF10400.9 OWF39158.1 - 5.6 7.7 7.4 4.7 8.0 0.9 3.4 3 1 0 3 3 3 0 Virulence activator alpha C-term Ras PF00071.22 OWF39159.1 - 8.9e-26 90.4 0.0 1.1e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF39159.1 - 1.2e-07 31.9 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OWF39159.1 - 0.00067 19.6 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OWF39159.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF39159.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 OWF39159.1 - 0.035 13.6 0.0 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family ATPase_2 PF01637.18 OWF39159.1 - 0.069 13.0 0.1 0.1 12.5 0.1 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 OWF39159.1 - 0.1 13.1 0.0 0.17 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF39159.1 - 0.12 12.7 0.0 0.37 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain p450 PF00067.22 OWF39163.1 - 5.2e-44 150.8 0.3 7.1e-44 150.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 UPF0061 PF02696.14 OWF39163.1 - 0.094 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Oscp1 PF10188.9 OWF39164.1 - 1.3e-75 253.3 7.1 2e-75 252.7 7.1 1.3 1 0 0 1 1 1 1 Organic solute transport protein 1 ADH_zinc_N PF00107.26 OWF39165.1 - 1.6e-14 54.0 0.0 2.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF39165.1 - 7.7e-11 41.8 0.1 2.1e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OWF39165.1 - 7.9e-06 27.0 0.0 1.5e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PapD-like PF14874.6 OWF39166.1 - 3.5e-11 43.1 0.0 7.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like Usp PF00582.26 OWF39166.1 - 0.61 10.6 3.6 0.9 10.0 0.1 3.1 2 0 0 2 2 2 0 Universal stress protein family Tim17 PF02466.19 OWF39167.1 - 1.8e-09 38.0 0.1 6.7e-07 29.7 0.2 2.4 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 OWF39167.1 - 7.5e-07 29.8 1.1 0.00086 19.9 0.2 2.7 3 0 0 3 3 3 2 N-terminal cysteine-rich region of Transmembrane protein 135 DUF4236 PF14020.6 OWF39167.1 - 0.0084 16.7 0.4 0.5 11.0 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4236) NHL PF01436.21 OWF39168.1 - 2.4e-06 27.3 5.3 0.0039 17.2 0.1 4.5 5 0 0 5 5 5 2 NHL repeat zf-B_box PF00643.24 OWF39168.1 - 0.00015 21.8 8.3 0.00035 20.6 8.3 1.7 1 0 0 1 1 1 1 B-box zinc finger Phytase-like PF13449.6 OWF39168.1 - 0.026 14.5 0.0 1.5 8.7 0.0 3.0 4 0 0 4 4 4 0 Esterase-like activity of phytase Exonuc_VII_L PF02601.15 OWF39168.1 - 0.05 13.2 2.0 0.1 12.2 2.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5616 PF18481.1 OWF39168.1 - 0.059 13.7 0.4 0.16 12.3 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5616) MSA-2c PF12238.8 OWF39168.1 - 0.088 12.8 5.2 0.023 14.7 2.2 1.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Reg_prop PF07494.11 OWF39168.1 - 0.14 12.5 4.0 1.5e+02 3.1 0.0 5.4 6 1 0 6 6 6 0 Two component regulator propeller MukF_M PF17192.4 OWF39168.1 - 0.14 11.9 6.0 0.26 11.0 6.0 1.4 1 0 0 1 1 1 0 MukF middle domain ZYG-11_interact PF05884.12 OWF39168.1 - 0.28 10.5 1.0 0.5 9.7 1.0 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 PBP_dimer PF03717.15 OWF39168.1 - 0.35 11.2 5.5 0.34 11.2 4.0 1.7 2 0 0 2 2 1 0 Penicillin-binding Protein dimerisation domain Spore_Cse60 PF10957.8 OWF39168.1 - 2.8 8.0 5.8 5.4 7.1 0.6 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 Golgin_A5 PF09787.9 OWF39168.1 - 6 6.2 14.7 1.3 8.4 11.2 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 OWF39168.1 - 7.6 6.6 14.5 0.53 10.4 1.6 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein PID PF00640.23 OWF39169.1 - 9.3e-17 61.4 0.2 9.3e-17 61.4 0.2 1.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 OWF39169.1 - 9.1e-13 48.5 0.1 1.5e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 OWF39169.1 - 6.9e-05 23.0 0.1 0.00011 22.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain TFIIE_alpha PF02002.17 OWF39170.1 - 1.1e-25 89.5 2.4 2e-25 88.7 2.4 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 OWF39170.1 - 3e-22 78.7 8.1 3e-22 78.7 8.1 2.5 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 OWF39170.1 - 3.4e-08 32.8 4.4 7.7e-08 31.7 4.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding LssY_C PF14067.6 OWF39170.1 - 0.0054 16.3 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 LssY C-terminus Rrf2 PF02082.20 OWF39170.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Acetyltransf_1 PF00583.25 OWF39171.1 - 8.4e-16 58.3 0.1 1.9e-15 57.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF39171.1 - 1.4e-13 51.1 0.2 8.7e-13 48.5 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF39171.1 - 4.8e-12 45.9 0.0 4.1e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF39171.1 - 1.5e-06 28.1 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OWF39171.1 - 0.00035 20.6 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OWF39171.1 - 0.0073 16.4 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OWF39171.1 - 0.035 13.8 0.1 0.2 11.4 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SPT16 PF08644.11 OWF39171.1 - 0.051 13.8 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Acetyltransf_6 PF13480.7 OWF39171.1 - 0.14 12.3 0.0 3.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CUB PF00431.20 OWF39172.1 - 1.6e-06 28.4 0.1 1.6e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 CUB domain Kazal_1 PF00050.21 OWF39173.1 - 1.4e-17 63.4 21.5 1.6e-08 34.4 7.6 2.5 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF39173.1 - 4.8e-13 49.0 17.8 6e-07 29.5 4.5 2.3 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Toxin_2 PF00451.19 OWF39173.1 - 0.0015 18.8 3.9 0.0015 18.8 3.9 2.8 3 0 0 3 3 3 1 Scorpion short toxin, BmKK2 Metallothio_Pro PF02069.16 OWF39173.1 - 0.46 10.8 15.6 0.38 11.0 5.6 2.3 1 1 1 2 2 2 0 Prokaryotic metallothionein Kazal_1 PF00050.21 OWF39174.1 - 2.6e-17 62.5 22.9 2e-08 34.1 7.8 2.7 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF39174.1 - 1.3e-12 47.7 21.7 2e-06 27.8 7.7 2.3 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Toxin_2 PF00451.19 OWF39174.1 - 0.0015 18.8 3.9 0.0015 18.8 3.9 2.9 3 0 0 3 3 3 1 Scorpion short toxin, BmKK2 Metallothio_Pro PF02069.16 OWF39174.1 - 0.42 10.9 18.4 0.55 10.5 8.2 2.3 1 1 1 2 2 2 0 Prokaryotic metallothionein DUF1096 PF06493.11 OWF39174.1 - 3.4 8.2 11.7 11 6.6 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) Kazal_1 PF00050.21 OWF39175.1 - 8.3e-17 60.9 22.2 3.5e-09 36.5 7.1 2.5 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF39175.1 - 1e-12 48.0 24.0 8.5e-08 32.2 5.6 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain DUF1096 PF06493.11 OWF39175.1 - 8.6 6.9 11.6 8.8 6.9 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) Kazal_1 PF00050.21 OWF39176.1 - 8.8e-22 76.9 31.2 8.9e-08 32.0 8.8 3.9 1 1 2 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF39176.1 - 7.5e-21 74.0 25.5 3.3e-08 33.5 5.4 3.6 2 2 1 3 3 3 3 Kazal-type serine protease inhibitor domain IFR3_antag PF14754.6 OWF39176.1 - 0.28 10.4 15.1 2.3 7.3 1.9 3.0 1 1 2 3 3 3 0 Papain-like auto-proteinase Kazal_1 PF00050.21 OWF39177.1 - 4.2e-16 58.7 17.6 4.7e-08 32.9 6.9 2.4 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF39177.1 - 7.6e-13 48.4 17.7 2.9e-06 27.3 5.1 2.3 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain NDUF_B4 PF07225.12 OWF39178.1 - 1.5e-05 24.9 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) MBT PF02820.18 OWF39179.1 - 1.4e-49 166.2 0.0 2.6e-26 91.7 0.0 2.9 3 0 0 3 3 3 2 mbt repeat SLED PF12140.8 OWF39179.1 - 4.4e-36 123.8 1.2 7.8e-36 123.0 1.2 1.4 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 OWF39179.1 - 1.9e-12 47.4 0.1 3.7e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF39179.1 - 8.5e-06 25.8 0.2 0.00016 21.8 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF39179.1 - 0.0028 17.6 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain CytochromB561_N PF09786.9 OWF39179.1 - 0.44 9.5 5.7 0.71 8.8 5.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal MFS_1 PF07690.16 OWF39180.1 - 1e-22 80.5 37.7 5.6e-13 48.5 19.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily GWT1 PF06423.12 OWF39180.1 - 0.062 13.4 0.7 0.18 11.9 0.7 1.9 1 0 0 1 1 1 0 GWT1 Glyco_hydro_3 PF00933.21 OWF39181.1 - 3.1e-48 164.8 0.0 1.1e-47 163.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OWF39181.1 - 1.3e-45 155.9 0.0 1.8e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OWF39181.1 - 2.6e-12 46.7 0.0 9.4e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 OWF39182.1 - 1.2e-45 156.0 0.0 1.7e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OWF39182.1 - 1.4e-45 156.1 0.0 4.2e-45 154.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OWF39182.1 - 3.8e-12 46.1 0.0 2e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain SASRP1 PF15160.6 OWF39183.1 - 2.9e-14 53.3 0.2 3.6e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated serine-rich protein 1 Pkinase PF00069.25 OWF39184.1 - 4.9e-40 137.6 0.0 7.5e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF39184.1 - 6.2e-19 68.3 0.0 1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF39184.1 - 2.2e-06 27.2 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF39184.1 - 0.00045 19.3 0.1 0.0012 17.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OWF39184.1 - 0.1 12.5 0.7 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OWF39184.1 - 0.11 11.8 2.8 0.15 11.4 0.4 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEPN_DZIP3 PF18738.1 OWF39185.1 - 9.2e-27 93.6 0.9 1.7e-26 92.7 0.9 1.5 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN WXG100 PF06013.12 OWF39185.1 - 0.0048 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Proteins of 100 residues with WXG HEPN_Cthe2314 PF18730.1 OWF39185.1 - 0.029 14.4 0.1 0.085 12.9 0.1 1.9 1 1 0 1 1 1 0 Cthe_2314-like HEPN EAP30 PF04157.16 OWF39185.1 - 0.056 12.7 0.5 0.088 12.1 0.1 1.6 2 0 0 2 2 2 0 EAP30/Vps36 family Peripla_BP_4 PF13407.6 OWF39185.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF4196 PF13846.6 OWF39185.1 - 0.24 11.6 2.9 0.51 10.6 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) LXG PF04740.12 OWF39185.1 - 0.6 9.8 4.3 2.9 7.5 2.4 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4355 PF14265.6 OWF39185.1 - 1.9 8.7 5.7 2.4 8.4 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) BIR PF00653.21 OWF39186.1 - 1.5e-32 112.1 8.2 1.8e-15 57.3 1.5 3.7 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain HMG14_17 PF01101.18 OWF39189.1 - 0.37 11.8 0.1 0.37 11.8 0.1 2.6 2 0 0 2 2 2 0 HMG14 and HMG17 F-box-like PF12937.7 OWF39190.1 - 2.3e-14 53.0 1.4 3.4e-14 52.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OWF39190.1 - 1.2e-09 37.8 0.1 2.9e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_9 PF14580.6 OWF39191.1 - 1.1e-10 41.4 0.6 2.3e-10 40.2 0.6 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF39191.1 - 1.7e-06 28.3 5.8 0.00064 20.1 0.7 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Macoilin PF09726.9 OWF39191.1 - 0.00012 20.9 9.2 0.00012 20.9 9.2 2.0 1 1 1 2 2 2 1 Macoilin family LRR_6 PF13516.6 OWF39191.1 - 0.00021 21.1 2.6 0.89 9.8 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 OWF39191.1 - 0.00036 20.2 6.0 0.00073 19.3 1.2 3.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 OWF39191.1 - 0.092 13.4 3.8 9.2 7.3 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat YabA PF06156.13 OWF39191.1 - 0.92 10.2 22.8 2.8 8.6 6.8 4.0 1 1 2 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OWF39191.1 - 1.1 9.3 22.6 0.61 10.1 8.6 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.13 OWF39191.1 - 3.5 7.7 16.1 1.4 9.0 11.5 2.7 1 1 1 2 2 2 0 DivIVA protein UPF0242 PF06785.11 OWF39191.1 - 6.5 6.8 27.7 0.41 10.7 9.3 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 OWF39192.1 - 1.7e-35 121.4 6.4 1.7e-14 54.1 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39192.1 - 6.9e-19 68.0 2.1 7.7e-08 32.7 0.1 4.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF39192.1 - 1.3e-18 66.5 2.5 0.0034 17.8 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OWF39192.1 - 7.9e-18 62.7 1.5 0.00047 20.4 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OWF39192.1 - 4.4e-15 55.6 4.5 5.3e-05 23.4 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) DUF1843 PF08898.10 OWF39192.1 - 0.051 14.1 0.8 11 6.6 0.1 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) zf-H2C2_2 PF13465.6 OWF39193.1 - 5.3e-37 124.6 69.1 8.4e-09 35.5 1.4 10.8 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2 PF00096.26 OWF39193.1 - 1.7e-31 106.9 83.4 2.8e-05 24.3 0.5 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF39193.1 - 1e-26 91.3 73.7 0.00052 20.6 0.2 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger GAGA PF09237.11 OWF39193.1 - 0.0014 18.3 0.7 0.016 15.0 0.0 3.0 3 0 0 3 3 3 1 GAGA factor zf-C2H2_jaz PF12171.8 OWF39193.1 - 0.0039 17.4 60.1 0.13 12.6 0.5 9.1 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF39193.1 - 0.0047 17.3 64.1 0.078 13.4 1.6 8.2 8 0 0 8 8 8 4 Zinc-finger of C2H2 type BolA PF01722.18 OWF39193.1 - 0.0054 17.0 4.6 0.32 11.3 0.3 3.7 2 1 1 3 3 3 1 BolA-like protein zf-Di19 PF05605.12 OWF39193.1 - 0.008 16.5 5.1 0.043 14.1 1.2 6.5 4 1 3 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 OWF39193.1 - 0.014 16.1 30.8 0.43 11.4 6.7 4.9 3 1 1 5 5 5 0 zinc-ribbon family zf-C2H2_6 PF13912.6 OWF39193.1 - 0.016 15.2 67.1 0.25 11.4 0.1 9.5 9 1 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF39193.1 - 0.13 12.0 0.1 0.13 12.0 0.1 7.3 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 OWF39193.1 - 0.17 11.6 0.2 0.068 12.9 7.3 9.5 8 2 0 8 8 7 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 OWF39193.1 - 2.1 8.7 32.0 0.44 10.9 2.5 4.9 2 1 3 5 5 5 0 C2H2-type zinc ribbon FYDLN_acid PF09538.10 OWF39193.1 - 9 7.0 28.1 0.069 13.8 2.5 5.0 5 2 1 6 6 6 0 Protein of unknown function (FYDLN_acid) EMP70 PF02990.16 OWF39194.1 - 3.5e-213 709.0 11.4 4.5e-213 708.6 11.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sulfotransfer_1 PF00685.27 OWF39195.1 - 5.4e-52 176.9 0.3 1.4e-49 169.0 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF39195.1 - 2.2e-06 28.2 0.0 3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family DNA_photolyase PF00875.18 OWF39196.1 - 9.9e-26 90.7 0.0 1.6e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase BRICHOS PF04089.14 OWF39197.1 - 5.3e-13 49.0 0.1 1.7e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 BRICHOS domain DUF2393 PF09624.10 OWF39197.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) SelP_N PF04592.14 OWF39197.1 - 0.3 10.5 2.9 0.49 9.8 2.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAIM1 PF06905.13 OWF39200.1 - 0.064 13.0 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) PHD PF00628.29 OWF39201.1 - 3.1e-09 36.6 8.8 8.7e-09 35.2 8.8 1.9 1 0 0 1 1 1 1 PHD-finger PMI_typeI PF01238.21 OWF39202.1 - 2.1e-110 369.4 0.0 3e-110 368.9 0.0 1.2 1 1 0 1 1 1 1 Phosphomannose isomerase type I EB1 PF03271.17 OWF39202.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 EB1-like C-terminal motif AraC_binding PF02311.19 OWF39202.1 - 0.07 13.0 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain RRM_1 PF00076.22 OWF39203.1 - 5.1e-09 35.8 0.1 1.5e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF39203.1 - 0.0011 19.1 0.0 0.0036 17.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OWF39203.1 - 0.0099 15.9 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TMEM126 PF07114.11 OWF39204.1 - 1e-10 41.3 0.3 1.3e-10 40.9 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 126 Ank_2 PF12796.7 OWF39205.1 - 7.3e-207 670.6 49.5 2.6e-12 47.1 0.1 24.8 1 1 26 27 27 27 26 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39205.1 - 4.1e-173 559.7 43.5 9.4e-10 38.8 0.0 31.5 19 6 16 35 35 35 31 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF39205.1 - 3.6e-140 454.2 59.8 1.6e-08 34.6 0.0 36.4 11 9 27 40 40 40 32 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39205.1 - 4.5e-118 370.7 43.8 0.015 15.8 0.0 46.1 47 1 0 47 47 47 28 Ankyrin repeat Ank PF00023.30 OWF39205.1 - 5.2e-93 301.8 86.4 0.058 13.9 0.1 46.2 46 2 2 48 48 48 32 Ankyrin repeat DUF4473 PF14747.6 OWF39205.1 - 0.018 15.6 0.0 52 4.5 0.0 6.3 8 0 0 8 8 8 0 Domain of unknown function (DUF4473) Med26 PF08711.11 OWF39206.1 - 5.7e-13 48.7 0.6 7.4e-12 45.1 0.0 2.6 3 0 0 3 3 3 1 TFIIS helical bundle-like domain SIKE PF05769.11 OWF39206.1 - 0.33 10.9 6.1 0.62 10.0 6.1 1.4 1 0 0 1 1 1 0 SIKE family SPATIAL PF15256.6 OWF39206.1 - 0.51 10.7 2.9 13 6.1 0.0 2.8 2 1 0 2 2 2 0 SPATIAL Lectin_C PF00059.21 OWF39207.1 - 0.0014 19.3 1.6 0.0014 19.3 1.6 3.1 2 2 0 2 2 2 1 Lectin C-type domain PAN_3 PF08277.12 OWF39207.1 - 0.0022 17.8 2.0 0.0071 16.1 2.0 1.9 1 0 0 1 1 1 1 PAN-like domain Reprolysin PF01421.19 OWF39208.1 - 6e-11 42.6 0.1 2.1e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 OWF39208.1 - 1.2e-08 35.1 10.8 1.2e-08 35.1 10.8 4.3 4 1 1 5 5 5 1 Thrombospondin type 1 domain Pep_M12B_propep PF01562.19 OWF39208.1 - 3.5e-08 33.8 0.0 8.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 OWF39208.1 - 5.7e-08 33.1 0.4 5.7e-08 33.1 0.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 ADAM_spacer1 PF05986.14 OWF39208.1 - 0.0028 17.7 0.0 0.0071 16.4 0.0 1.7 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin_4 PF13583.6 OWF39208.1 - 0.0048 16.6 1.9 0.0095 15.6 1.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF39208.1 - 0.0059 17.1 1.8 0.015 15.8 1.8 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF39208.1 - 0.039 13.8 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 Matrixin DUF2207 PF09972.9 OWF39209.1 - 0.00013 20.9 5.3 0.00073 18.4 0.0 2.2 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) DUF2157 PF09925.9 OWF39209.1 - 0.0037 17.1 4.9 0.55 10.0 1.4 2.7 1 1 1 2 2 2 2 Predicted membrane protein (DUF2157) Phage_holin_3_6 PF07332.11 OWF39209.1 - 0.0048 16.9 0.1 0.0048 16.9 0.1 2.8 2 1 1 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4079 PF13301.6 OWF39209.1 - 0.0062 16.7 0.6 0.013 15.7 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF4079) COX15-CtaA PF02628.15 OWF39209.1 - 0.013 14.6 1.4 0.019 14.0 1.4 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein CD20 PF04103.15 OWF39209.1 - 0.027 14.6 20.1 0.057 13.5 20.1 1.7 1 1 0 1 1 1 0 CD20-like family DUF4064 PF13273.6 OWF39209.1 - 0.044 14.1 0.1 0.044 14.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) DUF3185 PF11381.8 OWF39209.1 - 0.11 12.5 3.9 12 6.0 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) DUF5383 PF17355.2 OWF39209.1 - 0.2 12.0 0.3 89 3.5 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Bax1-I PF01027.20 OWF39209.1 - 0.21 11.4 10.9 0.043 13.6 6.2 1.9 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF2065 PF09838.9 OWF39209.1 - 0.69 10.0 6.5 3.9 7.6 0.8 3.4 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) TctB PF07331.11 OWF39209.1 - 0.83 9.9 9.9 1.9 8.7 9.9 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family AC_N PF16214.5 OWF39209.1 - 2.3 7.3 8.3 0.044 12.9 1.8 1.4 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region THAP PF05485.12 OWF39210.1 - 5.1e-14 53.0 1.8 7.9e-14 52.4 1.8 1.4 1 1 0 1 1 1 1 THAP domain SAP PF02037.27 OWF39211.1 - 0.013 15.2 0.7 0.018 14.8 0.7 1.2 1 0 0 1 1 1 0 SAP domain Fibrinogen_C PF00147.18 OWF39212.1 - 1.6e-56 191.5 4.2 2.1e-56 191.2 4.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain YpzG PF14139.6 OWF39212.1 - 0.12 12.5 0.1 0.69 10.1 0.0 2.1 1 1 1 2 2 2 0 YpzG-like protein TAS2R PF05296.13 OWF39213.1 - 0.25 10.4 0.5 0.42 9.7 0.0 1.5 2 0 0 2 2 2 0 Taste receptor protein (TAS2R) Podoplanin PF05808.11 OWF39214.1 - 0.13 12.3 4.4 0.18 11.9 3.7 1.4 1 1 0 1 1 1 0 Podoplanin CARD PF00619.21 OWF39215.1 - 0.027 14.5 0.9 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 Caspase recruitment domain Phytoreo_S7 PF07236.11 OWF39215.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein Dicty_CAR PF05462.11 OWF39216.1 - 1e-16 61.0 14.8 1.4e-16 60.5 14.8 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 OWF39216.1 - 2.3e-08 34.0 0.7 1.5e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Git3 PF11710.8 OWF39216.1 - 0.0019 18.0 19.2 0.0033 17.2 17.5 2.1 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 PIP49_C PF12260.8 OWF39218.1 - 7.2e-06 25.8 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 OWF39218.1 - 0.0078 15.5 1.1 0.098 11.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase UL2 PF08196.11 OWF39218.1 - 0.071 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 UL2 protein HC2 PF07382.11 OWF39219.1 - 0.0012 18.9 14.3 0.0017 18.5 14.3 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Spore_coat_CotO PF14153.6 OWF39219.1 - 0.094 12.6 13.4 0.12 12.3 13.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SID-1_RNA_chan PF13965.6 OWF39219.1 - 0.19 10.1 6.2 0.19 10.1 6.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF908 PF06012.12 OWF39219.1 - 0.28 10.5 24.4 0.43 10.0 24.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Spt20 PF12090.8 OWF39219.1 - 0.66 9.5 23.1 0.65 9.6 22.2 1.3 1 1 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.12 OWF39219.1 - 1.1 9.1 12.5 1.2 8.9 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 OWF39219.1 - 1.4 8.9 19.4 1.7 8.5 19.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3408 PF11888.8 OWF39219.1 - 1.7 8.8 15.0 3.1 7.9 15.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Sec3_C PF09763.9 OWF39219.1 - 1.7 6.9 16.1 2.3 6.5 16.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Zip PF02535.22 OWF39219.1 - 9.6 5.3 16.0 13 4.9 16.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Methyltransf_22 PF13383.6 OWF39220.1 - 7.4e-22 78.1 1.3 9.1e-22 77.8 1.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF39220.1 - 0.00042 20.4 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Autophagy_N PF03986.13 OWF39220.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain GDPD PF03009.17 OWF39221.1 - 1.1e-15 58.1 0.0 2.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Lig_chan-Glu_bd PF10613.9 OWF39222.1 - 1.2e-26 93.1 0.0 2.1e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 OWF39222.1 - 3.3e-18 66.0 0.0 3.5e-17 62.6 0.0 2.2 1 1 1 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OWF39222.1 - 3.8e-16 59.2 0.0 7e-16 58.3 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phage_holin_5_2 PF16079.5 OWF39222.1 - 0.038 14.3 0.2 0.038 14.3 0.2 3.5 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V FtsH_ext PF06480.15 OWF39222.1 - 0.07 13.5 0.6 0.07 13.5 0.6 3.2 4 0 0 4 4 4 0 FtsH Extracellular Sigma_reg_N PF13800.6 OWF39222.1 - 1 9.7 3.0 62 4.0 0.1 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal CBM_14 PF01607.24 OWF39223.1 - 0.00015 21.8 6.8 0.0003 20.9 6.8 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Branch PF02485.21 OWF39224.1 - 2.7e-43 148.3 0.1 3.5e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Zmiz1_N PF18028.1 OWF39224.1 - 0.023 15.0 0.3 3.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Zmiz1 N-terminal tetratricopeptide repeat domain AAA_5 PF07728.14 OWF39225.1 - 3.6e-102 338.0 0.0 3.3e-40 137.3 0.0 3.8 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF39225.1 - 1.6e-07 31.9 0.7 0.35 11.2 0.2 4.5 3 2 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 OWF39225.1 - 2.5e-05 23.9 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain CbbQ_C PF08406.10 OWF39225.1 - 7.2e-05 23.0 0.0 0.28 11.4 0.0 2.7 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_22 PF13401.6 OWF39225.1 - 0.00012 22.4 0.0 0.71 10.1 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OWF39225.1 - 0.00038 20.5 0.0 2.9 8.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 OWF39225.1 - 0.0028 17.2 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 OWF39225.1 - 0.0033 17.9 0.0 4.2 7.9 0.0 2.9 2 0 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.21 OWF39225.1 - 0.018 14.4 0.2 7.9 5.8 0.0 3.4 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OWF39225.1 - 0.041 13.8 0.1 2 8.3 0.1 3.5 4 0 0 4 4 4 0 NACHT domain Roc PF08477.13 OWF39225.1 - 0.042 14.1 0.1 2 8.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OWF39225.1 - 0.046 13.1 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 OWF39225.1 - 0.048 14.1 0.0 12 6.3 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 OWF39225.1 - 0.089 12.2 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OWF39225.1 - 0.13 12.8 0.0 0.92 10.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain Med29 PF11568.8 OWF39226.1 - 0.019 15.2 0.1 0.035 14.3 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 VWA_2 PF13519.6 OWF39226.1 - 0.085 13.5 0.2 0.43 11.2 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain EF-hand_1 PF00036.32 OWF39227.1 - 1.5e-13 49.2 2.8 0.00039 19.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF39227.1 - 6.5e-13 48.9 1.7 2.1e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF39227.1 - 2.6e-10 39.4 5.8 0.00068 19.4 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OWF39227.1 - 1.1e-08 34.2 4.6 0.0079 15.7 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF39227.1 - 1.6e-06 27.8 1.7 0.09 12.6 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF39227.1 - 0.00047 20.4 0.1 0.032 14.6 0.0 2.4 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF39227.1 - 0.0055 16.9 6.5 0.75 10.0 0.1 3.2 2 1 1 3 3 3 1 Dockerin type I domain Ish1 PF10281.9 OWF39227.1 - 0.018 15.4 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SinI PF08671.10 OWF39227.1 - 0.23 11.3 3.4 10 6.0 0.0 3.5 4 0 0 4 4 4 0 Anti-repressor SinI VCBS PF13517.6 OWF39227.1 - 2.3 8.9 7.9 77 4.0 0.0 3.7 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella VWD PF00094.25 OWF39228.1 - 7.4e-13 49.1 0.8 7.4e-13 49.1 0.8 2.5 2 0 0 2 2 2 1 von Willebrand factor type D domain Epiglycanin_C PF14654.6 OWF39228.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region EGF_Tenascin PF18720.1 OWF39228.1 - 0.13 12.3 10.0 0.65 10.1 10.0 2.4 1 0 0 1 1 1 0 Tenascin EGF domain Claudin_2 PF13903.6 OWF39228.1 - 0.53 10.0 1.5 0.93 9.2 0.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction EGF_2 PF07974.13 OWF39228.1 - 6.2 7.3 25.8 0.03 14.7 13.8 3.6 3 0 0 3 3 3 0 EGF-like domain TMEM154 PF15102.6 OWF39229.1 - 0.0048 16.8 0.0 0.0048 16.8 0.0 2.7 4 0 0 4 4 4 1 TMEM154 protein family EphA2_TM PF14575.6 OWF39229.1 - 0.22 12.4 2.8 1.4 9.8 0.0 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 OWF39229.1 - 1.1 9.3 5.5 7.5 6.7 0.0 3.1 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) VWD PF00094.25 OWF39231.1 - 8.6e-05 22.9 3.2 0.00065 20.0 0.2 2.7 1 1 1 2 2 2 1 von Willebrand factor type D domain EGF_2 PF07974.13 OWF39231.1 - 0.0084 16.5 12.4 0.0084 16.5 12.4 3.3 3 0 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 OWF39231.1 - 0.032 14.3 5.3 0.1 12.7 5.3 2.0 1 0 0 1 1 1 0 Tenascin EGF domain RGM_C PF06534.13 OWF39231.1 - 0.039 13.5 6.3 0.34 10.4 6.3 2.2 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Pkinase_Tyr PF07714.17 OWF39232.1 - 3.8e-74 249.2 0.0 5e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WIF PF02019.18 OWF39232.1 - 3.6e-40 136.7 0.3 6.6e-40 135.8 0.3 1.5 1 0 0 1 1 1 1 WIF domain Pkinase PF00069.25 OWF39232.1 - 2.8e-27 95.7 0.0 5e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF39232.1 - 0.0012 18.2 0.2 0.0033 16.8 0.2 1.6 1 1 0 1 1 1 1 Kinase-like Cwf_Cwc_15 PF04889.12 OWF39233.1 - 2e-73 247.2 25.4 6.8e-73 245.4 25.4 1.7 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Thiolase_N PF00108.23 OWF39233.1 - 0.11 11.8 0.6 0.16 11.3 0.6 1.1 1 0 0 1 1 1 0 Thiolase, N-terminal domain Acetyltransf_1 PF00583.25 OWF39234.1 - 2e-13 50.6 0.0 2.4e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF39234.1 - 6e-07 29.4 0.0 8.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF39234.1 - 2e-06 28.1 0.0 3.5e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF39234.1 - 4.2e-05 23.4 0.0 7.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_16 PF05301.11 OWF39234.1 - 0.0061 16.3 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 PanZ PF12568.8 OWF39234.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 OWF39234.1 - 0.039 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OWF39234.1 - 0.046 13.8 0.1 0.31 11.1 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OWF39234.1 - 0.085 13.0 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TSP_1 PF00090.19 OWF39236.1 - 3.1e-41 139.3 67.0 9e-13 48.2 7.1 5.5 6 0 0 6 6 6 4 Thrombospondin type 1 domain EGF PF00008.27 OWF39236.1 - 0.0022 18.3 9.1 0.0022 18.3 9.1 3.7 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 OWF39236.1 - 1 10.1 11.1 0.7 10.6 5.7 3.8 2 0 0 2 2 2 0 Human growth factor-like EGF DASH_Spc34 PF08657.10 OWF39242.1 - 0.02 14.7 3.4 0.027 14.3 3.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF2959 PF11172.8 OWF39242.1 - 0.061 13.5 1.3 0.082 13.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) UBA PF00627.31 OWF39243.1 - 1.3e-10 40.9 0.2 1.3e-10 40.9 0.2 1.9 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.16 OWF39243.1 - 0.00057 19.5 0.2 0.0025 17.5 0.1 2.2 2 0 0 2 2 2 1 CUE domain DER1 PF04511.15 OWF39243.1 - 0.0087 16.0 4.8 0.014 15.3 4.8 1.4 1 1 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 OWF39243.1 - 0.016 15.2 5.2 0.058 13.4 5.2 2.0 1 1 0 1 1 1 0 Rhomboid family WD40 PF00400.32 OWF39244.1 - 3e-69 227.2 18.4 1.6e-09 38.2 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF39244.1 - 6.6e-22 77.6 0.4 0.017 15.4 0.0 7.6 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF39244.1 - 1.7e-11 44.0 2.3 0.026 13.9 0.0 5.7 2 2 2 5 5 5 4 WD40-like domain eIF2A PF08662.11 OWF39244.1 - 9.5e-09 35.4 0.7 0.00093 19.1 0.0 3.6 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OWF39244.1 - 2.4e-07 29.8 3.6 2.7 6.6 0.0 6.2 1 1 5 7 7 7 4 Nucleoporin Nup120/160 CEP19 PF14933.6 OWF39244.1 - 0.00029 21.2 0.0 0.00043 20.6 0.0 1.3 1 0 0 1 1 1 1 CEP19-like protein Ge1_WD40 PF16529.5 OWF39244.1 - 0.00042 19.4 5.8 4.9 6.0 3.7 5.1 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MWFE PF15879.5 OWF39245.1 - 0.05 13.8 0.7 0.086 13.0 0.7 1.4 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit HtrL_YibB PF09612.10 OWF39246.1 - 4.6e-13 49.3 0.5 7e-13 48.7 0.5 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) SNARE PF05739.19 OWF39246.1 - 2.5 8.2 3.7 4.3 7.4 3.7 1.4 1 0 0 1 1 1 0 SNARE domain HPD PF05044.12 OWF39247.1 - 2.1e-05 24.5 6.2 17 5.2 0.0 6.6 1 1 5 7 7 7 3 Homeo-prospero domain UFD1 PF03152.14 OWF39247.1 - 0.00013 21.5 0.1 13 5.2 0.0 4.7 1 1 4 6 6 6 3 Ubiquitin fusion degradation protein UFD1 Nucleolin_bd PF16725.5 OWF39247.1 - 0.00042 19.9 0.0 5.9 6.6 0.0 5.1 2 2 3 6 6 6 1 Nucleolin binding domain TEP1_N PF05386.11 OWF39247.1 - 0.38 10.4 19.6 30 4.3 0.0 9.0 12 0 0 12 12 12 0 TEP1 N-terminal domain NAD_binding_10 PF13460.6 OWF39248.1 - 2.1e-35 122.3 0.0 2.4e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OWF39248.1 - 2.6e-06 27.1 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OWF39248.1 - 4.2e-05 23.2 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OWF39248.1 - 0.027 14.0 0.1 0.057 12.9 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 OWF39248.1 - 0.057 12.5 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.18 OWF39248.1 - 0.1 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF5563 PF17718.1 OWF39250.1 - 0.00072 19.2 1.0 0.015 14.9 0.5 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5563) Sugar_tr PF00083.24 OWF39251.1 - 1.2e-29 103.5 12.7 1.8e-29 102.9 12.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39251.1 - 1.2e-27 96.7 27.8 7.5e-23 81.0 17.5 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF39252.1 - 1.5e-30 106.5 17.2 2.4e-30 105.8 17.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39252.1 - 6e-29 101.1 52.3 1.3e-23 83.5 30.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4131 PF13567.6 OWF39252.1 - 0.025 14.3 0.1 0.025 14.3 0.1 3.8 3 1 2 5 5 5 0 Domain of unknown function (DUF4131) DUF3290 PF11694.8 OWF39252.1 - 0.15 12.0 0.4 0.32 11.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) PNMA PF14893.6 OWF39253.1 - 5.4e-06 26.0 0.1 1.6e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 PNMA zf-CCHC_3 PF13917.6 OWF39253.1 - 0.0098 15.8 0.8 0.019 14.9 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OWF39253.1 - 0.044 13.9 2.4 0.1 12.7 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1659 PF07872.11 OWF39253.1 - 0.077 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) Sugar_tr PF00083.24 OWF39254.1 - 3.3e-30 105.3 20.7 4.7e-30 104.8 20.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39254.1 - 4.6e-24 85.0 53.4 3.6e-20 72.2 30.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF39255.1 - 1.4e-23 83.5 17.4 1.4e-23 83.5 17.4 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39255.1 - 2e-21 76.3 22.4 2e-21 76.3 22.4 2.6 3 0 0 3 3 3 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF39256.1 - 1.1e-23 83.7 20.8 1.6e-23 83.3 20.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF39256.1 - 4.1e-21 75.4 16.0 2e-20 73.1 16.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 OWF39257.1 - 3.6e-30 105.2 16.3 3.6e-30 105.2 16.3 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39257.1 - 3.2e-22 78.9 42.5 1.4e-20 73.6 27.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OWF39257.1 - 0.074 12.9 3.8 0.062 13.1 1.5 1.9 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Corona_M PF01635.18 OWF39257.1 - 9.9 5.4 10.3 6.8 5.9 7.2 2.4 2 1 0 2 2 2 0 Coronavirus M matrix/glycoprotein LIM PF00412.22 OWF39258.1 - 2.2e-55 184.7 58.7 5.8e-15 55.3 4.6 5.3 5 0 0 5 5 5 5 LIM domain IgGFc_binding PF17517.2 OWF39259.1 - 4.5e-62 210.0 9.2 4.5e-62 210.0 9.2 2.1 2 0 0 2 2 2 1 IgGFc binding protein TSP_1 PF00090.19 OWF39259.1 - 6.6e-22 77.5 74.4 1e-07 32.0 12.2 5.5 5 0 0 5 5 5 4 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF39259.1 - 1.7e-06 28.1 9.9 1.7e-06 28.1 9.9 3.7 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A PPC PF04151.15 OWF39259.1 - 6.5 7.9 7.5 1.4 10.0 0.9 3.4 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Lectin_C PF00059.21 OWF39260.1 - 1.2e-09 38.9 0.0 1.5e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF39260.1 - 0.0002 21.1 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Tme5_EGF_like PF09064.10 OWF39260.1 - 0.0089 15.9 0.8 0.041 13.8 0.1 2.2 2 0 0 2 2 2 1 Thrombomodulin like fifth domain, EGF-like Lectin_C PF00059.21 OWF39261.1 - 7.3e-07 29.9 0.0 9.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF39261.1 - 0.0079 15.8 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF39262.1 - 1.7e-09 38.4 0.0 2.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF39262.1 - 0.00027 20.6 0.0 0.00031 20.5 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF229 PF02995.17 OWF39263.1 - 3.7e-121 405.2 2.3 9.6e-120 400.5 2.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF39263.1 - 8.5e-10 38.5 0.5 1.3e-09 37.9 0.5 1.2 1 0 0 1 1 1 1 Sulfatase DASH_Duo1 PF08651.10 OWF39264.1 - 0.014 15.1 1.8 0.43 10.4 0.1 2.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 SKA2 PF16740.5 OWF39264.1 - 0.018 14.8 6.1 0.093 12.5 4.2 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 KxDL PF10241.9 OWF39264.1 - 0.038 14.3 1.0 0.038 14.3 1.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein Vir_act_alpha_C PF10400.9 OWF39264.1 - 0.11 13.2 1.7 1.3 9.7 1.7 2.5 1 1 0 1 1 1 0 Virulence activator alpha C-term Rx_N PF18052.1 OWF39264.1 - 0.22 11.8 2.6 0.42 10.9 1.8 2.0 1 1 0 1 1 1 0 Rx N-terminal domain FliT PF05400.13 OWF39264.1 - 0.41 11.5 5.2 0.84 10.5 0.8 2.7 2 0 0 2 2 2 0 Flagellar protein FliT Sec20 PF03908.13 OWF39264.1 - 0.79 9.7 6.5 5.6 6.9 0.1 3.5 2 1 2 4 4 4 0 Sec20 Ninjurin PF04923.12 OWF39265.1 - 2.9e-30 104.2 0.1 3.4e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 Ninjurin TctB PF07331.11 OWF39265.1 - 0.0038 17.5 0.1 0.0046 17.2 0.1 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Prominin PF05478.11 OWF39265.1 - 0.0053 14.8 0.5 0.0062 14.6 0.5 1.0 1 0 0 1 1 1 1 Prominin Neuralized PF07177.12 OWF39266.1 - 0.089 12.8 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Neuralized YojJ PF10372.9 OWF39266.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus HALZ PF02183.18 OWF39266.1 - 0.15 12.3 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 OWF39266.1 - 0.35 11.0 1.8 0.29 11.3 0.3 1.6 2 0 0 2 2 2 0 bZIP transcription factor DUF5446 PF17522.2 OWF39267.1 - 0.067 13.4 0.8 0.088 13.0 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Ldl_recept_a PF00057.18 OWF39268.1 - 5.9e-11 42.4 13.7 8.4e-11 41.9 13.7 1.2 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF5446 PF17522.2 OWF39268.1 - 0.007 16.5 3.9 1.3 9.3 0.4 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5446) Mt_ATP-synt_D PF05873.12 OWF39268.1 - 0.01 15.7 0.4 0.99 9.2 0.1 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Sugarporin_N PF11471.8 OWF39268.1 - 0.049 13.6 5.0 0.19 11.7 1.1 2.2 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF3782 PF12644.7 OWF39268.1 - 0.1 12.7 0.9 0.17 12.0 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Cadherin PF00028.17 OWF39269.1 - 3.1e-32 110.9 10.5 6.8e-11 42.5 0.0 5.8 5 1 0 5 5 5 5 Cadherin domain TMEM126 PF07114.11 OWF39270.1 - 0.055 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 126 HSP70 PF00012.20 OWF39271.1 - 7.5e-11 40.9 0.2 1.4e-08 33.4 0.2 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF39271.1 - 0.00094 18.1 0.1 0.029 13.2 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 OWF39271.1 - 0.085 11.8 1.0 0.16 10.9 1.0 1.4 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain KGG PF10685.9 OWF39271.1 - 0.15 12.4 0.1 0.42 10.9 0.1 1.8 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif HSP70 PF00012.20 OWF39272.1 - 5e-12 44.8 0.2 4.6e-05 21.8 0.1 2.2 1 1 1 2 2 2 2 Hsp70 protein StbA PF06406.11 OWF39272.1 - 0.026 13.8 0.1 6.2 6.0 0.0 2.3 2 0 0 2 2 2 0 StbA protein DUF1018 PF06252.12 OWF39272.1 - 0.03 15.3 0.1 0.057 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) HSP70 PF00012.20 OWF39273.1 - 0.028 12.6 0.0 0.028 12.6 0.0 1.2 1 1 0 1 1 1 0 Hsp70 protein DUF2154 PF09922.9 OWF39273.1 - 0.12 12.3 0.0 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF BcrAD_BadFG PF01869.20 OWF39273.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF935 PF06074.12 OWF39274.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) MIEAP PF16026.5 OWF39275.1 - 7.9e-28 98.0 0.0 7.9e-28 98.0 0.0 3.8 3 1 0 3 3 3 1 Mitochondria-eating protein CENP-F_leu_zip PF10473.9 OWF39275.1 - 0.11 12.5 46.9 0.035 14.1 10.4 4.8 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC92 PF14916.6 OWF39275.1 - 0.35 10.7 8.5 0.65 9.8 0.1 3.8 3 0 0 3 3 3 0 Coiled-coil domain of unknown function RuvX PF03652.15 OWF39275.1 - 0.59 10.5 9.1 0.099 13.0 1.3 2.8 1 1 1 2 2 2 0 Holliday junction resolvase HSP70 PF00012.20 OWF39276.1 - 4.4e-10 38.4 0.0 3.2e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF39276.1 - 0.018 13.8 0.1 0.39 9.5 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein Gly_transf_sug PF04488.15 OWF39277.1 - 6.1e-11 42.8 0.1 1.7e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OWF39277.1 - 0.0019 17.6 0.8 0.0056 16.1 0.8 1.8 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 OWF39277.1 - 0.0027 17.1 1.2 0.0052 16.1 0.2 1.8 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain 7tm_1 PF00001.21 OWF39279.1 - 1e-53 182.3 11.3 2e-53 181.4 11.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF39279.1 - 4.1e-13 49.3 16.7 2.2e-12 46.9 16.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF39279.1 - 0.0029 17.3 14.7 0.0029 17.3 14.7 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Thymosin PF01290.20 OWF39280.1 - 6.8e-05 22.5 0.2 0.00022 20.9 0.0 2.1 1 1 1 2 2 2 1 Thymosin beta-4 family UPF0258 PF06789.12 OWF39280.1 - 0.056 13.6 1.1 0.091 12.9 1.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) Trypsin PF00089.26 OWF39281.1 - 9.3e-65 218.5 1.6 9.3e-65 218.5 1.6 1.7 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 OWF39281.1 - 2e-05 25.5 0.6 8.4e-05 23.5 0.2 2.2 2 1 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF39281.1 - 8e-05 23.0 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 OWF39281.1 - 0.015 14.9 0.0 2.7 7.5 0.0 2.4 3 0 0 3 3 3 0 Chymotrypsin family Peptidase-S1 zf-A20 PF01754.16 OWF39282.1 - 1.2e-12 47.5 7.4 1.2e-12 47.5 7.4 2.3 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 OWF39282.1 - 1.2e-08 34.9 10.5 1.2e-08 34.9 10.5 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger FSA_C PF10479.9 OWF39282.1 - 3.8 5.5 9.1 4.7 5.2 9.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fasciclin PF02469.22 OWF39283.1 - 1.1e-66 222.9 0.0 7.2e-21 74.7 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain DUF211 PF02680.14 OWF39283.1 - 0.092 12.9 1.8 5.8 7.1 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized ArCR, COG1888 UPF0728 PF15092.6 OWF39283.1 - 0.13 12.2 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 DUF3006 PF11213.8 OWF39284.1 - 0.058 13.6 1.2 0.2 11.9 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) TED PF08341.11 OWF39286.1 - 0.0075 16.6 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 Thioester domain PBP1_TM PF14812.6 OWF39287.1 - 1.5 9.2 10.8 0.072 13.5 4.1 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Di19 PF05605.12 OWF39288.1 - 0.0039 17.4 0.4 2.3 8.6 0.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF1059 PF06348.11 OWF39288.1 - 0.17 12.2 2.9 2.3 8.5 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) DTHCT PF08070.11 OWF39289.1 - 0.054 14.2 1.1 0.054 14.2 1.1 2.9 5 0 0 5 5 5 0 DTHCT (NUC029) region zf-Di19 PF05605.12 OWF39289.1 - 0.19 12.1 0.9 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RNase_H PF00075.24 OWF39290.1 - 0.031 14.5 0.3 0.045 13.9 0.3 1.2 1 0 0 1 1 1 0 RNase H RbsD_FucU PF05025.13 OWF39290.1 - 0.094 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family Lipase_GDSL PF00657.22 OWF39291.1 - 5.1e-09 36.4 0.0 6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF39291.1 - 3.1e-08 34.2 0.0 3.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF725 PF05267.12 OWF39291.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) HTH_38 PF13936.6 OWF39291.1 - 0.14 11.9 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4448 PF14610.6 OWF39292.1 - 0.054 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SEFIR PF08357.11 OWF39294.1 - 3.2e-12 47.0 0.1 5e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 SEFIR domain Syndecan PF01034.20 OWF39294.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 OWF39294.1 - 1.4 8.4 8.0 2.5 7.6 8.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Neurexophilin PF06312.12 OWF39295.1 - 2.6e-08 33.6 1.4 7.1e-08 32.2 0.5 2.0 1 1 1 2 2 2 1 Neurexophilin Filamin PF00630.19 OWF39295.1 - 0.057 14.2 0.0 0.28 12.0 0.0 2.1 2 0 0 2 2 2 0 Filamin/ABP280 repeat IL10 PF00726.17 OWF39296.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Interleukin 10 SET PF00856.28 OWF39297.1 - 3e-19 70.0 0.1 1e-17 65.1 0.1 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 OWF39297.1 - 5.7e-10 39.8 7.7 5.7e-10 39.8 7.7 2.3 2 0 0 2 2 2 1 Pre-SET motif Cyclotide PF03784.13 OWF39297.1 - 0.081 13.0 1.3 0.081 13.0 1.3 3.6 3 1 0 3 3 3 0 Cyclotide family DUF5374 PF17344.2 OWF39297.1 - 0.19 11.7 0.3 0.19 11.7 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5374) Ank_2 PF12796.7 OWF39298.1 - 2.1e-65 217.3 9.4 2.1e-16 60.3 0.1 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39298.1 - 1.4e-40 137.2 3.2 4.5e-06 27.1 0.0 7.1 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39298.1 - 1.7e-33 110.9 0.8 0.00019 21.6 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 OWF39298.1 - 4.2e-32 109.2 9.2 0.00035 20.9 0.0 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 OWF39298.1 - 1.5e-31 108.0 5.6 6.7e-06 26.3 0.0 7.6 2 2 6 8 8 8 8 Ankyrin repeats (many copies) DnaJ PF00226.31 OWF39300.1 - 1.8e-26 92.0 0.9 2.5e-26 91.6 0.9 1.2 1 0 0 1 1 1 1 DnaJ domain SCO1-SenC PF02630.14 OWF39300.1 - 0.042 13.8 0.2 0.059 13.3 0.2 1.2 1 0 0 1 1 1 0 SCO1/SenC PRAI PF00697.22 OWF39300.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase COG6 PF06419.11 OWF39301.1 - 1.4e-210 700.7 5.0 1.7e-210 700.5 5.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 OWF39301.1 - 0.01 15.7 4.9 0.01 15.7 4.9 2.9 3 1 1 4 4 4 0 Sec34-like family YabA PF06156.13 OWF39301.1 - 0.018 15.7 2.3 0.031 14.9 0.6 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CHASE3 PF05227.13 OWF39301.1 - 0.11 12.4 2.1 0.57 10.1 0.9 2.8 2 1 0 2 2 2 0 CHASE3 domain GyrB_insert PF18053.1 OWF39301.1 - 0.13 12.1 1.8 0.53 10.2 1.8 2.0 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain GAT PF03127.14 OWF39301.1 - 0.16 12.3 14.9 0.64 10.4 0.0 4.4 5 1 0 5 5 5 0 GAT domain BLOC1_2 PF10046.9 OWF39301.1 - 0.31 11.4 6.6 0.6 10.5 3.1 3.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynactin_p22 PF07426.11 OWF39301.1 - 1.4 8.7 9.2 1.7 8.5 5.3 2.6 2 1 0 2 2 2 0 Dynactin subunit p22 DUF1664 PF07889.12 OWF39301.1 - 1.7 8.7 5.8 13 5.9 4.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Troponin PF00992.20 OWF39301.1 - 2.6 8.4 6.8 0.54 10.5 2.6 2.1 2 0 0 2 2 2 0 Troponin SesA PF17107.5 OWF39301.1 - 3.1 8.0 9.3 2.2 8.5 0.0 3.6 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YtxH PF12732.7 OWF39301.1 - 5.9 7.5 5.6 18 6.0 1.0 3.5 4 1 0 4 4 3 0 YtxH-like protein TIMP PF00965.17 OWF39302.1 - 3.5e-18 66.0 2.8 5.6e-18 65.4 2.8 1.3 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF39302.1 - 0.00016 21.4 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module DUF1433 PF07252.11 OWF39302.1 - 0.13 12.6 0.6 5.8 7.2 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1433) TIMP PF00965.17 OWF39303.1 - 2.9e-07 30.5 0.0 3.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase TIMP PF00965.17 OWF39304.1 - 2.8e-05 24.0 0.0 3.6e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase Glycos_transf_4 PF00953.21 OWF39304.1 - 0.094 12.7 0.5 0.11 12.5 0.5 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 4 Neur_chan_memb PF02932.16 OWF39305.1 - 4.9e-17 62.8 1.2 6.6e-17 62.4 1.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region VWD PF00094.25 OWF39306.1 - 3.6e-19 69.6 33.0 1.3e-07 32.0 2.1 6.6 5 0 0 5 5 5 5 von Willebrand factor type D domain F5_F8_type_C PF00754.25 OWF39306.1 - 5.6e-14 52.4 4.3 5.6e-14 52.4 4.3 3.5 3 0 0 3 3 3 1 F5/8 type C domain EGF_2 PF07974.13 OWF39306.1 - 0.00051 20.3 33.8 0.00058 20.2 14.2 65.1 59 10 6 65 65 65 40 EGF-like domain B_lectin PF01453.24 OWF39306.1 - 0.87 10.2 2.5 15 6.2 0.3 3.6 3 0 0 3 3 3 0 D-mannose binding lectin MutS_III PF05192.18 OWF39307.1 - 2.2 8.5 4.6 9.3 6.4 4.6 2.2 1 1 0 1 1 1 0 MutS domain III Transp_inhibit PF18791.1 OWF39308.1 - 9.3e-08 31.5 10.5 15 5.2 0.0 7.0 7 0 0 7 7 7 2 Transport inhibitor response 1 protein domain McyA_C PF12593.8 OWF39308.1 - 1.5e-05 24.6 0.0 1.8e+02 2.0 0.0 6.6 7 0 0 7 7 7 0 Microcystin synthetase C terminal cEGF PF12662.7 OWF39308.1 - 1.9e-05 24.5 13.7 41 4.2 0.1 7.0 7 0 0 7 7 7 0 Complement Clr-like EGF-like UPF0547 PF10571.9 OWF39308.1 - 0.00014 21.9 9.0 34 4.7 0.2 6.5 1 1 4 5 5 5 0 Uncharacterised protein family UPF0547 Sushi PF00084.20 OWF39308.1 - 0.00073 20.1 6.4 1.2e+02 3.3 0.0 6.2 7 0 0 7 7 7 0 Sushi repeat (SCR repeat) Toxin_26 PF08097.11 OWF39308.1 - 0.23 12.2 22.9 30 5.6 0.3 6.8 7 0 0 7 7 7 0 Conotoxin T-superfamily Sp38 PF07354.12 OWF39308.1 - 0.93 8.9 10.5 51 3.2 0.3 5.1 1 1 6 7 7 7 0 Zona-pellucida-binding protein (Sp38) LRR_8 PF13855.6 OWF39309.1 - 5.3e-39 131.8 36.8 6e-13 48.3 3.3 8.7 5 2 3 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 OWF39309.1 - 2.1e-23 82.0 43.6 2.4e-07 31.0 1.0 8.7 7 1 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF39309.1 - 9.8e-18 64.4 0.0 1.6e-06 28.1 0.1 4.0 2 2 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF39309.1 - 5.7e-08 32.2 36.6 2 9.3 0.2 12.2 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_9 PF14580.6 OWF39309.1 - 0.00052 19.6 15.1 0.032 13.7 1.5 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 OWF39309.1 - 1 9.1 4.8 1.2 8.9 2.2 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain G-alpha PF00503.20 OWF39310.1 - 2.9e-122 408.3 9.0 3.3e-122 408.0 9.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OWF39310.1 - 1.1e-17 64.0 1.5 7.6e-13 48.3 0.8 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF39310.1 - 1.3e-05 24.7 5.8 0.0012 18.3 2.4 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OWF39310.1 - 0.0013 19.0 3.4 0.67 10.2 0.3 2.9 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OWF39310.1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 OWF39310.1 - 0.024 15.0 0.1 0.041 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OWF39310.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.22 OWF39310.1 - 0.085 12.4 3.6 1.8 8.1 1.5 2.3 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 OWF39310.1 - 0.097 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RabGAP-TBC PF00566.18 OWF39311.1 - 4.9e-50 170.2 1.7 7e-50 169.7 1.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Bromodomain PF00439.25 OWF39312.1 - 2.3e-89 293.6 24.7 8.7e-20 70.6 0.5 5.6 5 0 0 5 5 5 5 Bromodomain BAH PF01426.18 OWF39312.1 - 4e-38 130.0 5.6 1.3e-22 80.0 0.7 3.1 2 1 1 3 3 3 2 BAH domain HMG_box PF00505.19 OWF39312.1 - 1.1e-15 57.8 1.0 1.1e-15 57.8 1.0 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF39312.1 - 7.5e-10 39.3 2.7 7.5e-10 39.3 2.7 3.1 3 0 0 3 3 3 1 HMG-box domain CHDNT PF08073.12 OWF39312.1 - 0.013 15.5 0.2 0.099 12.6 0.0 2.6 3 0 0 3 3 3 0 CHDNT (NUC034) domain GTP_EFTU_D2 PF03144.25 OWF39312.1 - 0.18 12.2 0.1 5.1 7.6 0.0 3.1 4 0 0 4 4 4 0 Elongation factor Tu domain 2 ABC_membrane_2 PF06472.15 OWF39313.1 - 6.6e-93 311.0 8.6 8.6e-93 310.6 8.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OWF39313.1 - 1.7e-18 67.5 0.0 3.9e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF39313.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF39313.1 - 0.00052 19.5 0.0 0.28 10.6 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 OWF39313.1 - 0.0021 16.9 0.1 0.0036 16.1 0.1 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_23 PF13476.6 OWF39313.1 - 0.0034 17.9 1.0 0.0093 16.5 0.2 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OWF39313.1 - 0.0046 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 OWF39313.1 - 0.01 15.6 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OWF39313.1 - 0.072 13.4 0.0 0.35 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OWF39313.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 OWF39313.1 - 0.096 13.1 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Sugar_tr PF00083.24 OWF39315.1 - 7.6e-105 351.4 26.5 1.2e-80 271.6 16.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF39315.1 - 4.4e-34 118.0 15.6 4.4e-34 118.0 15.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OWF39315.1 - 2.3e-05 23.1 1.7 2.3e-05 23.1 1.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 OWF39315.1 - 0.0015 17.5 2.2 0.0015 17.5 2.2 2.1 2 0 0 2 2 2 1 MFS_1 like family DUF2530 PF10745.9 OWF39315.1 - 0.086 13.1 0.5 0.086 13.1 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) PSI_integrin PF17205.3 OWF39315.1 - 0.34 10.7 7.5 0.78 9.5 7.5 1.6 1 0 0 1 1 1 0 Integrin plexin domain VIT1 PF01988.19 OWF39315.1 - 0.86 9.4 8.3 1.3 8.8 4.7 2.6 2 0 0 2 2 2 0 VIT family UNC-93 PF05978.16 OWF39315.1 - 2.2 8.0 12.7 0.06 13.1 1.2 3.2 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 WIF PF02019.18 OWF39316.1 - 1.6e-27 95.8 0.0 2.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 WIF domain EGF PF00008.27 OWF39316.1 - 2e-13 50.4 54.9 0.00027 21.2 8.5 4.4 4 0 0 4 4 4 4 EGF-like domain EGF_2 PF07974.13 OWF39316.1 - 1.5e-06 28.4 72.5 0.0098 16.2 12.5 4.3 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 OWF39316.1 - 3.6e-06 27.4 53.6 0.0056 17.3 6.0 5.2 5 0 0 5 5 5 4 Human growth factor-like EGF DUF4407 PF14362.6 OWF39316.1 - 0.052 12.9 2.4 0.076 12.4 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Invasin_D3 PF09134.10 OWF39316.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Invasin, domain 3 Cadherin PF00028.17 OWF39317.1 - 3.5e-164 533.8 32.3 3e-21 75.7 0.0 11.4 11 0 0 11 11 11 11 Cadherin domain Cadherin_3 PF16184.5 OWF39317.1 - 1.1e-12 47.9 16.0 0.23 11.4 0.0 9.8 10 0 0 10 10 10 5 Cadherin-like Cadherin_2 PF08266.12 OWF39317.1 - 6.5e-08 32.3 0.0 0.084 12.7 0.0 5.6 5 0 0 5 5 5 2 Cadherin-like FctA PF12892.7 OWF39317.1 - 0.016 16.0 0.9 0.016 16.0 0.9 6.4 5 3 1 6 6 6 0 Spy0128-like isopeptide containing domain AIG1 PF04548.16 OWF39318.1 - 3.3e-68 229.2 0.4 3.3e-68 229.2 0.4 1.5 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF39318.1 - 1.6e-08 34.6 0.1 4e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF39318.1 - 0.0012 18.8 0.4 0.0037 17.2 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OWF39318.1 - 0.0019 17.8 0.1 0.0053 16.3 0.0 1.8 1 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OWF39318.1 - 0.002 18.2 10.1 0.052 13.6 0.4 3.4 2 2 1 3 3 3 2 Dynamin family zf-RanBP PF00641.18 OWF39318.1 - 0.0071 15.6 22.9 0.043 13.1 4.8 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Gtr1_RagA PF04670.12 OWF39318.1 - 0.039 13.3 2.5 0.062 12.6 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF39318.1 - 0.094 11.9 1.8 0.58 9.3 1.8 2.2 1 1 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 OWF39318.1 - 0.095 12.1 0.0 0.095 12.1 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OWF39318.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DZR PF12773.7 OWF39318.1 - 0.15 12.1 14.6 0.095 12.7 12.5 1.8 2 0 0 2 2 1 0 Double zinc ribbon FlxA PF14282.6 OWF39318.1 - 0.15 12.0 0.8 0.36 10.8 0.8 1.6 1 0 0 1 1 1 0 FlxA-like protein ABC_tran PF00005.27 OWF39318.1 - 0.77 10.3 11.3 0.64 10.5 4.0 2.8 1 1 1 2 2 2 0 ABC transporter DUF1690 PF07956.11 OWF39318.1 - 6.2 7.2 10.4 21 5.5 10.4 1.9 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Sulfotransfer_2 PF03567.14 OWF39319.1 - 9.3e-29 101.1 2.9 3.9e-27 95.8 0.5 2.5 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF39320.1 - 2.9e-28 99.5 2.0 4.2e-27 95.7 0.6 2.3 1 1 0 2 2 2 2 Sulfotransferase family PagL PF09411.10 OWF39321.1 - 0.0064 16.6 2.7 3.2 7.9 1.0 3.9 2 1 1 3 3 3 1 Lipid A 3-O-deacylase (PagL) HNOB PF07700.15 OWF39321.1 - 0.96 9.4 6.2 18 5.2 0.0 4.7 2 1 4 6 6 6 0 Haem-NO-binding Arena_nucleocap PF00843.17 OWF39321.1 - 2.2 7.1 11.8 5.4 5.8 1.0 4.5 1 1 2 4 4 4 0 Arenavirus nucleocapsid N-terminal domain Harakiri PF15196.6 OWF39322.1 - 0.00078 19.9 3.5 1.1e+02 3.4 0.0 6.6 1 1 7 8 8 8 0 Activator of apoptosis harakiri PagL PF09411.10 OWF39322.1 - 0.0035 17.5 5.9 5.8 7.1 1.1 4.9 2 1 2 4 4 4 2 Lipid A 3-O-deacylase (PagL) PagL PF09411.10 OWF39323.1 - 0.06 13.5 0.3 3.4 7.8 0.1 2.2 1 1 1 2 2 2 0 Lipid A 3-O-deacylase (PagL) Arena_nucleocap PF00843.17 OWF39323.1 - 0.25 10.2 4.0 6.9 5.5 0.1 3.1 1 1 3 4 4 4 0 Arenavirus nucleocapsid N-terminal domain Viral_DNA_bi PF02236.17 OWF39323.1 - 0.39 10.9 3.5 17 5.7 0.2 2.7 1 1 0 2 2 2 0 Viral DNA-binding protein, all alpha domain DUF1548 PF07579.11 OWF39323.1 - 2.6 8.4 9.4 11 6.3 1.6 2.5 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1548) LRR_6 PF13516.6 OWF39323.1 - 3.7 7.8 14.7 14 6.0 0.1 5.2 5 1 1 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.7 OWF39323.1 - 5.3 7.6 7.5 37 4.9 5.2 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF1397 PF07165.11 OWF39324.1 - 2.2e-07 30.5 10.5 6e-07 29.1 10.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1397) DUF19 PF01579.18 OWF39324.1 - 0.00013 21.8 7.3 0.0013 18.6 7.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF19) NRN1 PF15056.6 OWF39324.1 - 0.00056 20.0 2.2 0.34 11.0 0.1 2.4 1 1 1 2 2 2 2 Neuritin protein family CPG4 PF15481.6 OWF39324.1 - 0.012 16.3 9.1 1.3 9.7 1.9 3.0 1 1 2 3 3 3 0 Chondroitin proteoglycan 4 DUF1397 PF07165.11 OWF39325.1 - 3.4e-06 26.6 8.8 4.5e-06 26.2 8.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) CPG4 PF15481.6 OWF39325.1 - 8.6e-06 26.3 8.8 0.016 15.9 1.0 2.5 1 1 1 2 2 2 2 Chondroitin proteoglycan 4 DUF19 PF01579.18 OWF39325.1 - 0.003 17.4 6.4 0.11 12.2 6.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF19) Lipase PF00151.19 OWF39326.1 - 2.8e-81 273.5 0.0 3.8e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 OWF39326.1 - 4.1e-05 24.3 0.3 6.8e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF39326.1 - 0.0009 19.0 0.6 0.0022 17.7 0.6 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 OWF39326.1 - 0.0044 16.6 0.1 0.0087 15.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 OWF39326.1 - 0.047 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OWF39326.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 3) PT PF04886.12 OWF39327.1 - 0.87 9.2 155.9 0.059 12.9 6.1 16.3 10 5 1 11 11 11 0 PT repeat tRNA-synt_1c PF00749.21 OWF39328.1 - 3.3e-106 354.7 0.0 5.6e-106 354.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 OWF39328.1 - 2.2e-50 170.8 0.7 4.5e-50 169.8 0.7 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 OWF39328.1 - 4.1e-47 160.3 0.0 1e-46 159.0 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 OWF39328.1 - 3.4e-27 95.2 3.5 8e-27 94.0 3.5 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 eRF1_2 PF03464.15 OWF39328.1 - 0.12 12.7 0.2 0.47 10.8 0.1 2.0 2 0 0 2 2 2 0 eRF1 domain 2 Neurexophilin PF06312.12 OWF39330.1 - 6.1e-06 25.8 0.1 1e-05 25.1 0.1 1.4 1 1 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF39330.1 - 0.055 14.3 0.0 0.094 13.5 0.0 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat TIMP PF00965.17 OWF39331.1 - 1.9e-17 63.6 0.0 2.4e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF39331.1 - 1.5e-05 24.7 0.1 3.9e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 UNC-6/NTR/C345C module TIMP PF00965.17 OWF39332.1 - 4.6e-17 62.4 0.1 5.8e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF39332.1 - 5.3e-07 29.4 0.1 8.9e-07 28.7 0.1 1.4 1 1 0 1 1 1 1 UNC-6/NTR/C345C module 7tm_1 PF00001.21 OWF39333.1 - 4.2e-38 131.2 9.0 5.7e-38 130.7 9.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF39333.1 - 1.1e-09 38.0 10.3 2.8e-09 36.7 10.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF39333.1 - 1.6e-07 31.2 8.6 1.6e-07 31.2 8.6 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF39333.1 - 1e-06 28.3 11.8 3.5e-06 26.6 11.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 OWF39333.1 - 1.7e-06 28.0 4.9 3.1e-06 27.1 4.9 1.5 1 0 0 1 1 1 1 Olfactory receptor DUF2484 PF10658.9 OWF39333.1 - 0.019 15.2 2.1 0.13 12.6 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) Tmemb_9 PF05434.11 OWF39333.1 - 0.023 14.6 0.7 2 8.3 0.2 2.6 2 0 0 2 2 2 0 TMEM9 MHC2-interact PF09307.10 OWF39333.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting Sigma_reg_N PF13800.6 OWF39333.1 - 3.4 8.0 10.6 0.95 9.8 1.4 3.6 4 1 1 5 5 5 0 Sigma factor regulator N-terminal AbiEi_3_N PF17194.4 OWF39334.1 - 0.18 11.8 2.1 4 7.5 0.1 2.4 1 1 1 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain RP854 PF17460.2 OWF39334.1 - 0.2 11.4 6.1 1.9 8.2 1.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein RP854 DUF755 PF05501.11 OWF39334.1 - 2.9 8.2 7.0 1 9.6 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF755) DUF3715 PF12509.8 OWF39335.1 - 2.6e-35 121.6 0.0 2.6e-35 121.6 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF3715) SPOC PF07744.13 OWF39335.1 - 1.3e-05 25.2 0.0 4.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 SPOC domain TSP_1 PF00090.19 OWF39337.1 - 5.1e-48 161.1 107.6 5.7e-11 42.5 7.8 7.0 7 1 1 8 8 8 6 Thrombospondin type 1 domain CCDC66 PF15236.6 OWF39338.1 - 7.1e-21 74.6 26.4 7.1e-21 74.6 26.4 7.2 6 2 0 6 6 6 1 Coiled-coil domain-containing protein 66 Melibiase_2 PF16499.5 OWF39339.1 - 7.5e-143 474.8 0.8 8.9e-143 474.6 0.8 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 OWF39339.1 - 7.5e-11 42.1 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 OWF39339.1 - 9.3e-06 25.6 0.1 2.5e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OWF39339.1 - 1.5e-05 24.2 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase IBR PF01485.21 OWF39340.1 - 5.6e-12 45.7 41.1 4.1e-07 30.1 9.0 4.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OWF39340.1 - 0.014 15.4 11.1 0.014 15.4 11.1 3.6 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF39340.1 - 0.15 12.1 32.5 0.57 10.3 11.8 3.4 3 0 0 3 3 3 0 RING-type zinc-finger Sulfotransfer_3 PF13469.6 OWF39341.1 - 2.6e-09 37.8 0.0 5.1e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF39341.1 - 5.1e-09 36.0 0.7 4e-08 33.1 0.5 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Kunitz_BPTI PF00014.23 OWF39342.1 - 2e-16 59.9 7.5 3e-16 59.4 7.5 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain FeoB_associated PF12669.7 OWF39342.1 - 0.52 10.7 0.0 0.52 10.7 0.0 2.4 2 1 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Kunitz_BPTI PF00014.23 OWF39343.1 - 3.7e-19 68.7 3.9 4.2e-19 68.5 3.9 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain 7tm_2 PF00002.24 OWF39345.1 - 4.9e-67 225.8 18.1 6.5e-67 225.4 18.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF39345.1 - 2.1e-16 60.0 4.8 2.1e-16 60.0 4.8 2.3 3 0 0 3 3 3 1 Hormone receptor domain ANAPC4_WD40 PF12894.7 OWF39346.1 - 1e-09 38.6 1.1 0.012 15.9 0.0 6.0 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF39346.1 - 1.7e-08 34.6 0.1 0.01 15.7 0.0 3.7 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OWF39346.1 - 0.00024 21.8 13.6 0.024 15.5 0.2 5.9 6 1 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.12 OWF39346.1 - 0.00077 19.3 0.2 0.62 10.1 0.0 3.0 2 1 0 2 2 2 2 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 OWF39346.1 - 0.0026 16.9 0.0 0.41 9.6 0.0 2.5 1 1 0 1 1 1 1 Coatomer WD associated region IKI3 PF04762.12 OWF39346.1 - 0.021 12.9 0.6 1.1 7.1 0.0 2.5 2 1 0 2 2 2 0 IKI3 family WDCP PF15390.6 OWF39346.1 - 0.48 8.8 13.4 0.98 7.7 5.1 3.1 3 1 1 4 4 4 0 WD repeat and coiled-coil-containing protein family FLYWCH PF04500.16 OWF39346.1 - 0.75 9.9 3.0 1.5 9.0 3.0 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Nucleos_tra2_C PF07662.13 OWF39347.1 - 4.9e-78 261.7 4.1 4.9e-78 261.7 4.1 2.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF39347.1 - 6.3e-24 84.4 4.8 6.3e-24 84.4 4.8 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OWF39347.1 - 3.6e-08 33.7 7.1 3.6e-08 33.7 7.1 3.8 3 1 0 3 3 3 1 Nucleoside recognition Ectatomin PF06457.11 OWF39347.1 - 0.16 11.9 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Ectatomin LANC_like PF05147.13 OWF39348.1 - 7.8e-83 278.0 1.9 9e-83 277.8 1.9 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.13 OWF39348.1 - 0.00085 18.5 0.3 0.018 14.1 0.1 2.5 3 0 0 3 3 3 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 OWF39348.1 - 0.0089 15.5 6.2 0.015 14.8 0.1 2.7 2 1 1 3 3 3 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 OWF39348.1 - 0.015 13.8 0.3 0.032 12.7 0.1 1.6 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 CitF PF04223.12 OWF39348.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Glyco_hydro_76 PF03663.14 OWF39348.1 - 0.36 10.3 3.5 5 6.5 0.8 2.6 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 DUF1356 PF07092.12 OWF39349.1 - 2.9e-53 180.5 2.1 3.7e-53 180.2 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 OWF39349.1 - 0.00078 19.9 0.2 0.0015 19.0 0.2 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein Anti-TRAP PF15777.5 OWF39349.1 - 0.00084 19.3 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3267 PF11667.8 OWF39349.1 - 0.058 13.7 0.9 0.082 13.2 0.1 1.6 2 0 0 2 2 2 0 Putative zincin peptidase ZU5 PF00791.20 OWF39350.1 - 1.6e-06 28.4 0.0 4.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 ZU5 domain TNFR_c6 PF00020.18 OWF39350.1 - 0.00064 20.1 1.3 0.00064 20.1 1.3 5.4 6 0 0 6 6 6 3 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 OWF39350.1 - 0.001 18.8 17.6 0.017 14.8 3.8 4.3 3 0 0 3 3 3 3 Putative ephrin-receptor like MFS_1 PF07690.16 OWF39351.1 - 3.2e-14 52.6 53.0 1.4e-11 43.9 45.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OWF39352.1 - 2.6e-18 66.1 43.2 2.6e-18 66.1 43.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Inositol_P PF00459.25 OWF39353.1 - 5.4e-24 85.1 3.1 1.3e-22 80.6 3.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 OWF39354.1 - 8.2e-73 245.0 0.7 1.2e-72 244.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF39354.1 - 9.6e-35 120.1 0.0 2.4e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF39354.1 - 1.3e-05 24.3 0.2 1.3e-05 24.3 0.2 2.7 3 0 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 OWF39354.1 - 0.0001 21.8 0.0 0.00038 19.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like MPLKIP PF15502.6 OWF39355.1 - 4.2e-11 42.9 3.1 5.4e-11 42.5 0.3 2.4 2 0 0 2 2 2 1 M-phase-specific PLK1-interacting protein DUF5423 PF17461.2 OWF39355.1 - 0.65 8.8 3.4 1 8.2 3.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) WD40 PF00400.32 OWF39356.1 - 9.7e-13 48.4 20.0 0.0025 18.6 0.6 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 OWF39356.1 - 4.5e-07 29.4 13.6 4.5e-07 29.4 13.6 2.6 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 OWF39356.1 - 3e-06 27.4 3.4 0.099 13.0 0.2 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Csa1 PF06023.12 OWF39356.1 - 0.025 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Choline_sulf_C PF12411.8 OWF39356.1 - 0.077 12.8 0.5 0.67 9.8 0.1 2.6 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal zinc_ribbon_16 PF17034.5 OWF39356.1 - 0.51 10.5 17.0 1.6 9.0 15.1 2.8 3 1 0 3 3 3 0 Zinc-ribbon like family DZR PF12773.7 OWF39356.1 - 7.3 6.7 12.1 0.8 9.8 6.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon PA28_beta PF02252.18 OWF39357.1 - 1.1e-61 206.8 0.1 1.6e-61 206.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 OWF39357.1 - 5.3e-18 64.8 0.4 1e-17 63.9 0.4 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Nramp PF01566.18 OWF39358.1 - 2.9e-120 401.5 13.6 2.9e-120 401.5 13.6 2.0 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein Nramp PF01566.18 OWF39359.1 - 1e-118 396.5 11.6 1e-118 396.5 11.6 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein MtN3_slv PF03083.16 OWF39360.1 - 3.5e-39 132.7 22.1 9.5e-23 80.1 1.7 2.4 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange MPC PF03650.13 OWF39360.1 - 0.094 12.9 0.1 0.094 12.9 0.1 2.4 2 1 1 3 3 3 0 Mitochondrial pyruvate carriers PQ-loop PF04193.14 OWF39360.1 - 0.28 11.0 0.0 0.28 11.0 0.0 4.8 5 2 1 6 6 6 0 PQ loop repeat Ipi1_N PF12333.8 OWF39361.1 - 1.1e-23 83.8 1.6 2.1e-19 70.0 0.1 4.2 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation SesA PF17107.5 OWF39361.1 - 0.094 12.9 0.8 2.8 8.1 0.1 3.2 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Pkinase PF00069.25 OWF39362.1 - 5.5e-43 147.2 0.0 1.4e-42 145.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF39362.1 - 5.9e-28 97.9 0.0 2.3e-27 95.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF39362.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-4CXXC_R1 PF10497.9 OWF39363.1 - 4e-36 123.2 13.0 6e-36 122.6 13.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 SR-25 PF10500.9 OWF39363.1 - 0.078 12.6 5.8 0.12 12.0 5.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Putative_PNPOx PF01243.20 OWF39364.1 - 3.5e-22 78.4 0.0 7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 OWF39364.1 - 5e-19 68.1 0.4 1.1e-18 67.0 0.4 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 OWF39364.1 - 1.5e-06 28.8 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 OWF39364.1 - 0.0022 17.6 0.1 0.0078 15.8 0.0 1.8 1 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase like Mt_ATP-synt_D PF05873.12 OWF39364.1 - 0.093 12.6 0.3 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Amidase_2 PF01510.25 OWF39365.1 - 1.4e-18 67.5 0.4 2.7e-18 66.6 0.4 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Guanylate_cyc PF00211.20 OWF39366.1 - 3.1e-115 382.2 0.1 7.9e-58 195.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 OWF39366.1 - 3.2e-44 151.7 2.9 3.2e-44 151.7 2.9 2.5 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 OWF39366.1 - 5.4e-08 33.3 0.4 1.6e-07 31.8 0.4 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) PRIMA1 PF16101.5 OWF39366.1 - 0.0017 18.4 6.0 0.0017 18.4 6.0 3.2 3 0 0 3 3 3 1 Proline-rich membrane anchor 1 Colicin_K PF17500.2 OWF39366.1 - 0.56 10.8 9.2 0.21 12.2 3.7 2.6 2 0 0 2 2 2 0 Colicin-K PKD_channel PF08016.12 OWF39367.1 - 5.4e-86 288.9 13.6 1.1e-85 287.9 13.6 1.6 1 0 0 1 1 1 1 Polycystin cation channel REJ PF02010.15 OWF39367.1 - 4.1e-50 170.9 0.4 1.6e-49 169.0 0.4 2.0 1 0 0 1 1 1 1 REJ domain PKD PF00801.20 OWF39367.1 - 7.8e-17 60.9 37.5 4.5e-07 29.6 0.2 7.4 7 1 0 7 7 7 4 PKD domain PLAT PF01477.23 OWF39367.1 - 7.6e-15 55.5 0.0 4.3e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 PLAT/LH2 domain Ion_trans PF00520.31 OWF39367.1 - 1.9e-10 40.4 29.9 1.9e-10 40.4 29.9 2.8 3 0 0 3 3 3 1 Ion transport protein GPS PF01825.21 OWF39367.1 - 0.0029 18.1 3.5 0.0029 18.1 3.5 2.6 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DUF2981 PF11200.8 OWF39367.1 - 0.029 14.1 0.8 0.099 12.4 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PKD_channel PF08016.12 OWF39368.1 - 1e-75 255.1 20.6 1e-75 255.1 20.6 2.2 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.15 OWF39368.1 - 1.9e-50 172.0 5.3 1.9e-50 172.0 3.5 1.9 2 0 0 2 2 2 1 REJ domain PLAT PF01477.23 OWF39368.1 - 2.6e-13 50.5 1.2 1.2e-12 48.4 0.1 2.8 2 0 0 2 2 2 1 PLAT/LH2 domain PKD PF00801.20 OWF39368.1 - 5.6e-11 42.1 5.7 0.061 13.2 0.1 6.4 7 0 0 7 7 7 4 PKD domain Ion_trans PF00520.31 OWF39368.1 - 2.9e-07 30.0 26.6 2.9e-07 30.0 26.6 2.6 3 0 0 3 3 3 1 Ion transport protein DUF3937 PF13073.6 OWF39368.1 - 0.44 10.7 2.4 1.4 9.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) GPS PF01825.21 OWF39368.1 - 0.62 10.6 8.7 0.093 13.3 2.7 2.7 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif PKD PF00801.20 OWF39369.1 - 9.1e-23 79.9 2.0 2e-05 24.3 0.0 6.3 6 1 0 6 6 6 5 PKD domain PKD_channel PF08016.12 OWF39370.1 - 2.3e-82 276.9 12.8 5.1e-82 275.8 12.8 1.6 1 0 0 1 1 1 1 Polycystin cation channel REJ PF02010.15 OWF39370.1 - 5e-36 124.5 0.3 1.1e-35 123.4 0.3 1.4 1 0 0 1 1 1 1 REJ domain PLAT PF01477.23 OWF39370.1 - 2e-15 57.4 0.1 4.9e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 OWF39370.1 - 4.8e-12 45.6 28.2 4.8e-12 45.6 28.2 3.6 3 1 1 4 4 4 1 Ion transport protein GPS PF01825.21 OWF39370.1 - 0.0034 17.9 5.4 0.0034 17.9 5.4 3.0 4 0 0 4 4 4 1 GPCR proteolysis site, GPS, motif AP1AR PF15745.5 OWF39371.1 - 1.5e-21 77.2 12.4 2.1e-21 76.8 12.4 1.2 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein G-alpha PF00503.20 OWF39372.1 - 8.2e-105 350.8 4.6 9.4e-105 350.6 4.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OWF39372.1 - 2.1e-15 56.6 1.6 3.4e-10 39.6 0.1 3.4 2 1 1 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF39372.1 - 0.0063 16.6 0.0 0.96 9.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF39372.1 - 0.0097 15.3 2.3 0.18 11.1 0.2 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF39372.1 - 0.031 13.8 0.1 1 8.9 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 OWF39372.1 - 0.059 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pro_3_hydrox_C PF05373.11 OWF39372.1 - 0.062 13.4 0.2 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal FtsK_SpoIIIE PF01580.18 OWF39372.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 OWF39372.1 - 0.084 13.1 0.2 2.1 8.6 0.0 3.1 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OWF39372.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M3 PF01432.20 OWF39373.1 - 3.2e-58 198.1 0.1 4.8e-58 197.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 Perilipin PF03036.16 OWF39373.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Perilipin family UQ_con PF00179.26 OWF39374.1 - 4.9e-22 78.1 0.0 1.1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4314 PF14192.6 OWF39374.1 - 0.1 12.5 0.0 0.4 10.6 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) CDC45 PF02724.14 OWF39374.1 - 0.61 8.3 15.0 0.11 10.7 2.4 2.3 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.13 OWF39374.1 - 1.1 9.3 24.3 0.12 12.5 4.0 3.1 3 0 0 3 3 3 0 YL1 nuclear protein DDDD PF10161.9 OWF39375.1 - 2.2e-24 85.0 0.1 2.5e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Putative mitochondrial precursor protein Pkinase_Tyr PF07714.17 OWF39376.1 - 1e-30 106.9 0.0 2.6e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF39376.1 - 1e-21 77.5 0.0 3.1e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 OWF39376.1 - 5.8e-13 49.1 0.0 1e-06 29.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF39376.1 - 2.1e-09 37.8 0.0 5.6e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF39376.1 - 4.2e-05 23.6 0.0 0.015 15.8 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OWF39376.1 - 0.00013 22.2 0.1 0.062 13.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OWF39376.1 - 0.0058 16.9 0.0 0.02 15.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Mito_carr PF00153.27 OWF39377.1 - 3e-66 219.4 3.6 9.8e-25 86.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 OWF39377.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Fuseless NPR3 PF03666.13 OWF39378.1 - 6e-30 104.5 2.6 6e-30 104.5 2.6 1.6 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 MMR_HSR1_Xtn PF16897.5 OWF39379.1 - 7.4e-41 138.5 0.2 1.6e-40 137.4 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OWF39379.1 - 1.8e-22 79.6 0.1 3.3e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 OWF39379.1 - 2.7e-22 78.6 0.1 4.6e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OWF39379.1 - 6e-14 51.8 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OWF39379.1 - 0.00054 20.1 0.1 1.3 9.0 0.1 2.4 1 1 1 2 2 2 2 Dynamin family AAA_28 PF13521.6 OWF39379.1 - 0.019 15.2 0.1 0.042 14.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OWF39379.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 OWF39379.1 - 0.054 12.5 0.2 0.18 10.8 0.1 1.9 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OWF39379.1 - 0.08 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OWF39379.1 - 0.094 12.6 0.8 0.23 11.3 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 OWF39379.1 - 0.14 12.7 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter IF4E PF01652.18 OWF39380.1 - 5.6e-56 188.7 0.8 6.6e-56 188.5 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 OWF39381.1 - 1.4e-21 77.1 0.0 2.6e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF39381.1 - 1.2e-14 54.3 0.0 2.6e-14 53.1 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase PND PF17949.1 OWF39382.1 - 3.3e-12 46.7 0.0 6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 FANCM pseudonuclease domain HHH_2 PF12826.7 OWF39382.1 - 1.9e-09 37.5 0.1 2.8e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OWF39382.1 - 0.00017 22.1 0.1 0.00024 21.6 0.1 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain Pkinase PF00069.25 OWF39383.1 - 7e-55 186.2 0.0 8.4e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF39383.1 - 2.2e-39 135.3 0.0 2.8e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF39383.1 - 4.5e-05 22.9 0.0 7.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF39383.1 - 0.00013 21.0 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OWF39383.1 - 0.0077 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OWF39383.1 - 0.0078 15.0 0.0 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 OWF39383.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OWF39383.1 - 0.037 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tweety PF04906.13 OWF39384.1 - 2.4e-73 247.1 3.7 2.8e-73 246.9 3.7 1.0 1 0 0 1 1 1 1 Tweety SUR7 PF06687.12 OWF39384.1 - 0.0017 18.0 1.9 0.0017 18.0 1.9 2.8 3 0 0 3 3 3 1 SUR7/PalI family Bac_rhodopsin PF01036.18 OWF39384.1 - 0.012 15.2 5.0 2.4 7.7 0.0 2.3 1 1 0 2 2 2 0 Bacteriorhodopsin-like protein ETRAMP PF09716.10 OWF39384.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.3 2 2 2 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) YfhO PF09586.10 OWF39384.1 - 2.2 6.4 8.0 0.24 9.6 1.8 2.0 2 1 0 2 2 2 0 Bacterial membrane protein YfhO PARG_cat PF05028.14 OWF39385.1 - 1.3e-136 455.3 0.0 1.9e-136 454.8 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Ribosomal_S24e PF01282.19 OWF39386.1 - 5.1e-41 138.5 0.5 7.9e-41 137.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e 7tm_1 PF00001.21 OWF39387.1 - 3.7e-77 259.2 2.4 5.7e-77 258.6 2.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF39387.1 - 3.6e-10 39.6 6.5 1.7e-05 24.3 8.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 OWF39387.1 - 1.3e-06 28.0 7.0 0.00019 20.9 5.6 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 OWF39387.1 - 0.0011 18.8 10.0 1.7 8.3 10.6 2.9 2 1 0 2 2 2 2 Olfactory receptor DUF4079 PF13301.6 OWF39387.1 - 0.018 15.2 0.6 5.8 7.1 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) ALMT PF11744.8 OWF39387.1 - 0.066 12.0 6.8 0.11 11.3 6.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Phage_holin_3_6 PF07332.11 OWF39387.1 - 0.19 11.8 8.3 3.3 7.8 0.0 3.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Glycophorin_A PF01102.18 OWF39387.1 - 0.44 10.8 2.6 1.1 9.5 0.1 2.6 3 0 0 3 3 3 0 Glycophorin A 7TM_GPCR_Str PF10326.9 OWF39387.1 - 0.61 9.4 12.1 1.6 8.0 12.1 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Spore_III_AB PF09548.10 OWF39387.1 - 1.7 8.7 4.3 0.51 10.4 0.2 2.2 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF3659 PF12396.8 OWF39388.1 - 0.023 14.6 0.2 0.047 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) 7tm_1 PF00001.21 OWF39389.1 - 1.6e-31 109.6 7.6 1.9e-31 109.3 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF39389.1 - 0.00075 18.9 11.8 0.098 11.9 4.8 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Stevor PF17410.2 OWF39389.1 - 0.0087 15.6 0.4 0.016 14.8 0.4 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 OWF39389.1 - 0.028 14.3 0.5 0.34 10.8 0.2 2.3 2 0 0 2 2 2 0 TMEM154 protein family S1FA PF04689.13 OWF39389.1 - 1.9 8.7 9.0 5.4 7.2 0.2 3.1 3 0 0 3 3 3 0 DNA binding protein S1FA Pox_EPC_I2-L1 PF12575.8 OWF39389.1 - 4.5 7.6 11.3 13 6.1 0.2 3.3 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 DUF2700 PF10912.8 OWF39389.1 - 5 7.1 11.5 0.68 9.9 0.8 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2700) ANAPC4_WD40 PF12894.7 OWF39391.1 - 4.7e-08 33.2 0.2 0.048 14.0 0.1 4.0 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF39391.1 - 0.00042 21.1 0.0 10 7.1 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40_like PF17005.5 OWF39391.1 - 0.13 11.6 0.1 14 4.9 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain zf-DBF PF07535.12 OWF39392.1 - 3.3e-17 62.3 3.8 1.3e-16 60.4 3.8 2.2 1 0 0 1 1 1 1 DBF zinc finger Med1 PF10744.9 OWF39396.1 - 4.3e-53 180.9 0.5 4.3e-53 180.9 0.5 2.0 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Ras PF00071.22 OWF39397.1 - 7.9e-57 191.4 0.3 9.8e-57 191.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF39397.1 - 7.9e-21 74.5 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF39397.1 - 3.3e-10 39.7 0.0 4.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF39397.1 - 1.5e-07 31.5 0.1 0.0004 20.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OWF39397.1 - 3.9e-06 26.5 0.2 1.4e-05 24.7 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF39397.1 - 0.00074 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF39397.1 - 0.013 15.1 0.1 0.06 12.9 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OWF39397.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GW PF13457.6 OWF39397.1 - 0.079 13.6 0.3 7.7 7.2 0.0 2.5 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain AAA_25 PF13481.6 OWF39397.1 - 0.095 12.3 0.1 0.16 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF1353 PF07087.11 OWF39397.1 - 0.095 12.4 0.1 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Aldedh PF00171.22 OWF39397.1 - 0.73 8.3 3.0 0.33 9.4 0.8 1.4 2 0 0 2 2 2 0 Aldehyde dehydrogenase family Sterol-sensing PF12349.8 OWF39399.1 - 1e-49 168.3 7.0 1.8e-49 167.5 7.0 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OWF39399.1 - 2.2e-19 69.1 4.8 3.3e-19 68.5 4.8 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 OWF39399.1 - 8.3e-12 45.4 12.1 0.054 14.4 0.1 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF39399.1 - 2.7e-06 27.6 0.5 0.86 9.9 0.0 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 OWF39399.1 - 0.18 10.9 0.0 8.6 5.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) DUF1689 PF07954.11 OWF39399.1 - 0.22 11.9 1.7 2.8 8.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1689) zf-CW PF07496.15 OWF39400.1 - 8.6e-13 48.1 8.0 2.4e-12 46.7 8.0 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger ARID PF01388.21 OWF39400.1 - 1.6e-12 47.9 0.0 3.6e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PWWP PF00855.17 OWF39400.1 - 1e-11 45.1 2.1 2.3e-11 43.9 0.1 2.6 2 0 0 2 2 2 1 PWWP domain GCIP PF13324.6 OWF39401.1 - 1.4e-09 38.0 0.1 3.7e-09 36.6 0.1 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting BAAT_C PF08840.11 OWF39403.1 - 3.1e-30 105.7 0.0 1.8e-29 103.2 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 OWF39403.1 - 2.7e-28 98.6 0.0 4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 OWF39403.1 - 1.2e-06 28.2 0.1 9.6e-05 22.0 0.1 3.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 OWF39404.1 - 0.0024 17.7 0.0 0.0071 16.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ets PF00178.22 OWF39405.1 - 1.9e-30 105.1 1.4 4.2e-30 104.0 1.4 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 OWF39405.1 - 2.1e-07 30.8 0.1 4.7e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain YqaJ PF09588.10 OWF39408.1 - 1.1e-09 38.6 0.2 2.2e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain SAP PF02037.27 OWF39408.1 - 0.00052 19.7 0.0 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF2390 PF09523.10 OWF39408.1 - 0.092 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) THAP PF05485.12 OWF39411.1 - 3.3e-05 24.7 0.2 0.00021 22.2 0.0 2.2 2 0 0 2 2 2 1 THAP domain EGF_MSP1_1 PF12946.7 OWF39414.1 - 0.6 10.2 3.6 19 5.4 0.3 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 U71 PF17474.2 OWF39416.1 - 0.018 15.0 0.5 54 3.8 0.0 5.1 5 2 2 7 7 7 0 Tegument protein UL11 homolog PTR PF12789.7 OWF39416.1 - 0.044 13.8 0.1 8.3 6.6 0.0 2.5 1 1 3 4 4 4 0 Phage tail repeat like Neugrin PF06413.11 OWF39416.1 - 0.05 13.6 1.0 53 3.7 0.0 5.0 2 2 6 8 8 8 0 Neugrin CCD PF07860.11 OWF39416.1 - 0.24 11.5 0.3 9.2 6.3 0.0 2.7 2 1 1 3 3 3 0 WisP family C-Terminal Region zf-C2H2 PF00096.26 OWF39417.1 - 9.7e-34 114.0 83.6 0.00018 21.8 1.7 12.8 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF39417.1 - 1.4e-32 109.5 78.6 0.0002 22.0 1.4 12.8 13 0 0 13 13 12 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF39417.1 - 5e-23 80.5 74.6 3.3e-05 24.1 0.2 12.4 12 0 0 12 12 12 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF39417.1 - 8e-20 70.6 34.8 0.013 15.7 0.2 10.9 10 0 0 10 10 10 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF39417.1 - 5.6e-12 45.4 67.0 3.2e-05 23.8 0.3 12.7 13 0 0 13 13 13 7 C2H2-type zinc finger zf-met PF12874.7 OWF39417.1 - 4.5e-07 30.1 56.7 0.026 14.9 0.1 11.7 12 1 0 12 12 12 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OWF39417.1 - 0.0003 20.5 43.9 0.25 11.1 0.1 10.4 10 0 0 10 10 10 3 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 OWF39417.1 - 0.00048 20.4 41.6 0.026 14.8 4.2 6.4 2 1 3 6 6 5 3 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 OWF39417.1 - 0.0092 16.3 57.8 0.15 12.4 0.4 7.4 1 1 6 7 7 7 3 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 OWF39417.1 - 0.041 14.0 42.7 1.4 9.1 2.0 8.4 6 3 3 9 9 9 0 Zinc ribbon domain BolA PF01722.18 OWF39417.1 - 1.1 9.6 5.7 1.4 9.3 0.6 3.5 4 1 0 4 4 4 0 BolA-like protein AT_hook PF02178.19 OWF39417.1 - 2.2 8.4 6.7 6.1 7.1 6.7 1.8 1 0 0 1 1 1 0 AT hook motif zf_UBZ PF18439.1 OWF39417.1 - 2.7 7.6 28.5 1 9.0 0.4 8.6 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 OWF39417.1 - 9.7 7.0 40.6 2.1 9.1 1.2 6.6 3 1 3 6 6 6 0 zinc-ribbon family zf-C2H2 PF00096.26 OWF39418.1 - 1.6e-26 91.2 150.0 0.00031 21.0 0.7 17.8 17 0 0 17 17 17 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF39418.1 - 1.2e-25 88.0 151.6 0.0026 18.5 2.0 18.4 19 0 0 19 19 19 13 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF39418.1 - 4.3e-11 42.7 128.2 6.9e-05 23.1 3.8 18.6 20 0 0 20 20 20 7 Zinc-finger double domain zf-C2H2_11 PF16622.5 OWF39418.1 - 3.6e-05 23.4 12.0 0.0017 18.0 0.3 13.0 14 0 0 14 14 14 7 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OWF39418.1 - 9.1e-05 22.6 84.5 0.0081 16.4 1.1 13.2 15 0 0 15 15 15 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF39418.1 - 0.00022 21.1 0.4 0.00022 21.1 0.4 15.0 16 0 0 16 16 16 4 C2H2-type zinc finger zf-met PF12874.7 OWF39418.1 - 0.0052 17.1 0.7 0.0052 17.1 0.7 15.2 16 0 0 16 16 16 6 Zinc-finger of C2H2 type zf-C2HE PF16278.5 OWF39418.1 - 0.074 13.5 0.1 0.074 13.5 0.1 11.8 9 3 1 10 10 10 0 C2HE / C2H2 / C2HC zinc-binding finger DUF1661 PF07877.11 OWF39419.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) Antistasin PF02822.14 OWF39420.1 - 0.0014 19.2 6.9 0.0014 19.2 6.9 3.0 3 0 0 3 3 3 2 Antistasin family LRR_9 PF14580.6 OWF39422.1 - 7.7e-12 45.1 3.5 1.4e-11 44.2 3.5 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF39422.1 - 4.5e-10 39.6 11.3 1.4e-06 28.5 0.6 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF39422.1 - 1.7e-07 30.9 11.7 3.5e-06 26.7 5.7 3.5 3 0 0 3 3 3 1 Leucine rich repeat SpoVT_C PF15714.5 OWF39422.1 - 0.0049 16.9 0.6 0.008 16.2 0.1 1.6 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor MHCassoc_trimer PF08831.10 OWF39422.1 - 0.017 15.1 0.4 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain ROS_MUCR PF05443.11 OWF39422.1 - 0.025 14.6 0.9 0.044 13.8 0.1 1.8 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein SPT6_acidic PF14632.6 OWF39422.1 - 0.43 11.2 8.2 0.095 13.3 4.5 1.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 LRR_6 PF13516.6 OWF39422.1 - 1.9 8.7 11.3 2 8.7 2.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat PIN_11 PF18479.1 OWF39423.1 - 6.2e-37 126.4 0.0 1.3e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 PIN like domain PIN7 PF18475.1 OWF39423.1 - 0.0088 16.7 0.0 0.023 15.3 0.0 1.8 1 0 0 1 1 1 1 PIN domain zf-C2H2_4 PF13894.6 OWF39423.1 - 1.1 10.2 23.9 1 10.4 0.6 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger AAA PF00004.29 OWF39425.1 - 3.5e-43 147.2 0.0 9.5e-43 145.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF39425.1 - 1.7e-12 47.0 0.0 4.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OWF39425.1 - 1.3e-07 31.5 0.2 3.1e-07 30.2 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OWF39425.1 - 3.9e-07 30.3 0.2 1.3e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OWF39425.1 - 2e-06 27.9 0.0 1e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF39425.1 - 2.6e-06 27.9 0.1 6.8e-05 23.3 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OWF39425.1 - 6.3e-05 23.3 0.3 0.0071 16.6 0.3 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OWF39425.1 - 9.3e-05 22.2 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OWF39425.1 - 0.0013 19.2 0.3 0.013 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 OWF39425.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OWF39425.1 - 0.0019 17.4 0.0 0.0046 16.2 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OWF39425.1 - 0.0022 17.7 0.2 0.0049 16.6 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein RILP PF11461.8 OWF39425.1 - 0.0049 17.1 2.5 0.014 15.6 2.5 1.8 1 0 0 1 1 1 1 Rab interacting lysosomal protein Mg_chelatase PF01078.21 OWF39425.1 - 0.0064 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OWF39425.1 - 0.0071 15.8 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 OWF39425.1 - 0.0088 15.9 0.0 0.025 14.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OWF39425.1 - 0.015 14.6 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 OWF39425.1 - 0.015 15.5 0.2 0.033 14.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 OWF39425.1 - 0.019 14.7 0.1 0.11 12.2 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 OWF39425.1 - 0.026 14.9 0.1 0.54 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OWF39425.1 - 0.027 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OWF39425.1 - 0.03 14.0 0.0 0.077 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OWF39425.1 - 0.039 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FapA PF03961.13 OWF39425.1 - 0.044 12.4 1.6 0.071 11.7 1.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF815 PF05673.13 OWF39425.1 - 0.046 12.9 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 OWF39425.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OWF39425.1 - 0.054 13.3 0.9 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OWF39425.1 - 0.058 12.5 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 OWF39425.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 OWF39425.1 - 0.061 12.9 0.3 0.16 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 OWF39425.1 - 0.066 12.4 1.2 0.58 9.3 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 OWF39425.1 - 0.091 12.0 0.2 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 OWF39425.1 - 0.093 12.4 0.4 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OWF39425.1 - 0.098 13.0 0.1 0.36 11.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF39425.1 - 0.11 13.1 0.2 0.99 9.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter DUF2075 PF09848.9 OWF39425.1 - 0.13 11.5 1.8 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MscS_porin PF12795.7 OWF39425.1 - 0.14 11.6 6.0 0.23 11.0 6.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CHGN PF05679.16 OWF39426.1 - 3.6e-127 425.3 2.6 4.5e-127 425.0 2.6 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 OWF39426.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 Fringe-like Cystatin PF00031.21 OWF39426.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Cystatin domain Adeno_E3 PF06040.11 OWF39426.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Adenovirus E3 protein RhoGAP PF00620.27 OWF39427.1 - 2.5e-43 147.5 0.0 4.3e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 OWF39427.1 - 1.4e-13 50.6 8.8 3e-06 27.2 0.1 3.6 2 1 1 3 3 3 3 WW domain PH PF00169.29 OWF39427.1 - 4.8e-08 33.5 0.1 1.5e-07 31.9 0.1 1.9 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 OWF39427.1 - 1.9e-05 24.2 1.3 3.2e-05 23.4 0.4 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OWF39427.1 - 7e-05 22.6 0.2 0.00018 21.3 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH_9 PF15410.6 OWF39427.1 - 0.089 13.2 0.9 0.42 11.0 0.3 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain FH2 PF02181.23 OWF39429.1 - 2.4e-100 336.3 11.5 2.4e-100 336.3 11.5 2.4 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 OWF39429.1 - 7.2e-39 133.4 19.1 7.2e-39 133.4 19.1 3.0 2 1 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OWF39429.1 - 1.6e-29 102.8 5.0 1.6e-29 102.8 5.0 4.0 4 2 1 5 5 5 1 Diaphanous GTPase-binding Domain DUF572 PF04502.13 OWF39429.1 - 0.0042 16.8 0.6 0.0042 16.8 0.6 2.7 3 1 0 3 3 3 1 Family of unknown function (DUF572) DEC-1_N PF04625.13 OWF39429.1 - 0.17 10.8 7.0 0.41 9.6 7.0 1.6 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region COMP PF11598.8 OWF39429.1 - 0.21 12.1 5.8 0.064 13.7 1.3 2.6 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DUF2682 PF10909.8 OWF39429.1 - 1.2 9.7 6.7 5.7 7.5 1.0 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) DUF4201 PF13870.6 OWF39429.1 - 1.5 8.5 32.2 0.095 12.4 15.3 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) VIT1 PF01988.19 OWF39429.1 - 4.5 7.1 8.0 0.9 9.4 3.5 2.2 2 0 0 2 2 2 0 VIT family IPPT PF01715.17 OWF39429.1 - 6.7 6.5 8.6 4.8 6.9 0.1 3.1 2 1 1 3 3 3 0 IPP transferase Aldo_ket_red PF00248.21 OWF39430.1 - 6.5e-47 160.1 0.0 5.3e-46 157.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family 2-Hacid_dh_C PF02826.19 OWF39431.1 - 1.5e-55 187.4 0.0 2.5e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF39431.1 - 7.5e-40 135.7 0.1 1.1e-39 135.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 OWF39431.1 - 0.0077 15.8 0.1 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 OWF39431.1 - 0.11 13.1 0.6 8.2 7.1 0.1 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WBP-1 PF11669.8 OWF39432.1 - 6.7e-10 39.5 3.8 1.2e-09 38.8 3.8 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 Acyl_transf_3 PF01757.22 OWF39432.1 - 0.0096 15.0 3.0 0.011 14.8 3.0 1.1 1 0 0 1 1 1 1 Acyltransferase family RCR PF12273.8 OWF39432.1 - 0.021 15.5 0.5 0.037 14.7 0.1 1.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Comm PF15957.5 OWF39432.1 - 0.027 14.8 0.2 0.046 14.1 0.2 1.4 1 0 0 1 1 1 0 Commissureless DUF4636 PF15468.6 OWF39432.1 - 0.17 11.6 2.7 0.2 11.3 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) TMEM52 PF14979.6 OWF39432.1 - 0.6 10.0 8.5 1.7 8.6 5.7 2.2 2 0 0 2 2 2 0 Transmembrane 52 DUF3522 PF12036.8 OWF39432.1 - 1.9 8.7 11.8 1.1 9.6 5.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3522) DUF1971 PF09313.11 OWF39433.1 - 0.00033 20.6 8.9 32 4.7 0.0 6.7 4 1 4 8 8 8 1 Domain of unknown function (DUF1971) DUF4744 PF15918.5 OWF39433.1 - 0.0089 16.8 0.0 0.27 12.1 0.0 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4744) Heliorhodopsin PF18761.1 OWF39433.1 - 0.15 11.3 12.6 0.13 11.6 1.3 3.0 1 1 2 3 3 3 0 Heliorhodopsin Pox_T4_C PF04490.12 OWF39433.1 - 7.2 6.8 8.8 12 6.1 0.1 3.3 1 1 3 4 4 4 0 Poxvirus T4 protein, C terminus UvrD_C_2 PF13538.6 OWF39433.1 - 8.7 6.3 15.4 14 5.6 0.2 5.0 5 0 0 5 5 5 0 UvrD-like helicase C-terminal domain DUF2816 PF10992.8 OWF39434.1 - 9.9e-07 28.6 40.2 0.049 13.5 1.4 7.8 2 2 5 7 7 7 6 Protein of unknown function (DUF2816) PLDc_3 PF13918.6 OWF39434.1 - 4.4 6.9 6.9 1.4 8.6 0.7 2.9 2 2 1 3 3 3 0 PLD-like domain zf-C4 PF00105.18 OWF39435.1 - 8.2e-27 93.5 13.4 8.2e-27 93.5 13.4 2.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF39435.1 - 1.8e-23 83.2 0.0 3.2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ATP-synt_F6 PF05511.11 OWF39435.1 - 0.031 14.7 0.4 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Nucleos_tra2_C PF07662.13 OWF39436.1 - 1e-73 247.6 7.2 1e-73 247.6 7.2 3.8 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF39436.1 - 5e-25 87.9 5.1 3.1e-24 85.4 5.1 2.4 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OWF39436.1 - 8.5e-10 38.9 6.9 8.5e-10 38.9 6.9 3.5 4 0 0 4 4 4 1 Nucleoside recognition Vma12 PF11712.8 OWF39436.1 - 0.073 13.1 0.7 0.71 9.9 0.0 2.9 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Orf78 PF06024.12 OWF39436.1 - 1.5 9.2 20.3 3.9 7.8 0.1 4.3 4 1 1 5 5 5 0 Orf78 (ac78) DUF3671 PF12420.8 OWF39436.1 - 4.4 7.4 14.6 0.038 14.1 3.4 3.0 3 0 0 3 3 3 0 Protein of unknown function Fibrinogen_C PF00147.18 OWF39437.1 - 3.7e-44 151.2 6.4 5.5e-44 150.6 6.4 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain TSP_1 PF00090.19 OWF39437.1 - 1.9e-07 31.2 9.3 1.9e-07 31.2 9.3 3.1 2 1 1 3 3 3 1 Thrombospondin type 1 domain Neur_chan_LBD PF02931.23 OWF39438.1 - 9.9e-45 152.6 0.7 1.4e-44 152.2 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF39438.1 - 5e-18 66.0 11.0 2.8e-16 60.3 5.3 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF3043 PF11241.8 OWF39438.1 - 3.2 7.8 4.5 0.88 9.6 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) HLH PF00010.26 OWF39439.1 - 5.3e-16 58.3 0.1 9.8e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF773 PF05600.12 OWF39439.1 - 0.00081 18.2 0.2 0.0015 17.3 0.2 1.3 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 HTH_51 PF18558.1 OWF39439.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HLH PF00010.26 OWF39440.1 - 1.9e-17 63.0 0.2 4e-17 61.9 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 OWF39440.1 - 0.0014 18.4 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 OWF39440.1 - 0.011 14.6 0.5 0.015 14.1 0.5 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Nucleoporin_C PF03177.14 OWF39440.1 - 0.016 14.0 0.4 0.019 13.7 0.4 1.0 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal CCDC106 PF15794.5 OWF39440.1 - 0.13 11.9 5.2 0.17 11.5 5.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 zf-C3HC4 PF00097.25 OWF39441.1 - 3.9e-07 29.8 8.4 3.9e-07 29.8 8.4 3.6 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF39441.1 - 2.8e-06 27.4 8.2 2.8e-06 27.4 8.2 3.2 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF39441.1 - 1.1e-05 25.3 8.9 1.1e-05 25.3 8.9 3.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF39441.1 - 0.00011 21.9 5.1 0.00011 21.9 5.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF39441.1 - 0.00029 20.9 7.8 0.00029 20.9 7.8 4.0 4 1 0 4 4 3 2 B-box zinc finger Prok-RING_4 PF14447.6 OWF39441.1 - 0.0007 19.4 6.0 0.0007 19.4 6.0 3.2 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OWF39441.1 - 0.0011 18.8 9.2 0.0011 18.8 9.2 3.8 4 1 0 4 4 1 1 Zinc finger, C3HC4 type (RING finger) Apolipoprotein PF01442.18 OWF39441.1 - 0.0067 16.3 6.1 0.012 15.4 6.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain zf-RING_5 PF14634.6 OWF39441.1 - 0.0085 16.0 8.6 0.0085 16.0 8.6 3.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OWF39441.1 - 0.047 13.6 3.9 0.11 12.4 2.5 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF3829 PF12889.7 OWF39441.1 - 0.055 12.9 1.0 0.09 12.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) OmpH PF03938.14 OWF39441.1 - 0.14 12.5 4.1 0.26 11.6 4.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 OWF39441.1 - 0.14 12.4 1.8 0.43 10.9 1.2 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SGL PF08450.12 OWF39441.1 - 0.16 11.5 0.3 0.57 9.7 0.0 2.0 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF3919 PF13057.6 OWF39441.1 - 0.28 10.7 2.1 1.1 8.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) Baculo_PEP_C PF04513.12 OWF39441.1 - 0.41 10.7 3.9 2.1 8.4 1.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 OWF39441.1 - 0.55 10.3 2.8 2.1 8.4 2.8 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Trm112p PF03966.16 OWF39441.1 - 0.83 10.3 3.8 18 6.0 3.8 2.7 1 1 0 1 1 1 0 Trm112p-like protein Exonuc_VII_L PF02601.15 OWF39441.1 - 4.1 6.9 8.1 10 5.6 8.0 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit 3HCDH_N PF02737.18 OWF39442.1 - 3.2e-57 193.3 0.0 4.9e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 OWF39442.1 - 6.1e-35 120.7 0.2 2.1e-34 119.0 0.1 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 OWF39442.1 - 7.8e-32 109.8 0.0 1.6e-22 79.9 0.1 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 OWF39442.1 - 1.1e-20 74.4 0.3 3.8e-20 72.7 0.2 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OWF39442.1 - 0.026 14.5 0.0 5.1 7.0 0.0 2.7 3 0 0 3 3 3 0 Peptidase family S49 NAD_binding_2 PF03446.15 OWF39442.1 - 0.074 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OWF39442.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ATP-grasp_2 PF08442.10 OWF39442.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain LRR_4 PF12799.7 OWF39443.1 - 4.3e-07 30.2 16.0 0.38 11.2 1.4 7.7 6 1 2 9 9 9 3 Leucine Rich repeats (2 copies) F-box PF00646.33 OWF39443.1 - 5.2e-06 26.2 0.8 5.2e-06 26.2 0.8 3.0 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 OWF39443.1 - 1.5e-05 24.8 3.3 1.9e-05 24.4 1.6 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 OWF39443.1 - 0.00032 20.6 0.1 0.00032 20.6 0.1 2.7 4 0 0 4 4 4 1 F-box LRR_6 PF13516.6 OWF39443.1 - 0.085 12.9 16.9 20 5.6 0.3 7.3 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 OWF39443.1 - 0.2 12.4 24.5 1.7 9.5 0.0 7.7 8 1 0 8 8 8 0 Leucine Rich Repeat C1q PF00386.21 OWF39444.1 - 3.7e-20 72.4 0.0 4.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 OWF39445.1 - 6e-18 65.3 0.1 7.7e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF39445.1 - 3.6e-05 23.7 1.1 5.5e-05 23.1 0.5 1.5 1 1 0 1 1 1 1 BclA C-terminal domain Big_3_5 PF16640.5 OWF39445.1 - 0.069 13.3 1.9 0.11 12.7 1.5 1.5 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) KorB_C PF06613.11 OWF39446.1 - 0.02 14.9 0.0 0.084 12.9 0.0 2.1 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain FXa_inhibition PF14670.6 OWF39446.1 - 0.021 15.1 4.2 0.021 15.1 4.2 2.6 1 1 2 3 3 3 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 OWF39446.1 - 1 9.8 10.2 4.4 7.7 10.2 2.1 1 0 0 1 1 1 0 EGF-like domain Pkinase_Tyr PF07714.17 OWF39447.1 - 6.3e-46 156.8 0.0 1.4e-45 155.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF39447.1 - 1.4e-23 83.6 0.0 2.2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 OWF39447.1 - 0.0033 17.1 0.1 0.014 15.0 0.0 2.0 3 0 0 3 3 3 1 RIO1 family SRTM1 PF15872.5 OWF39447.1 - 0.025 14.7 0.1 0.054 13.6 0.1 1.6 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF4690 PF15756.5 OWF39447.1 - 0.1 13.2 1.6 8.4 7.1 0.1 2.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Ldh_2 PF02615.14 OWF39448.1 - 1.6e-103 346.4 0.0 1.8e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 OWF39449.1 - 1.8e-104 349.5 0.3 2e-104 349.3 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 OWF39450.1 - 2.4e-107 358.9 0.1 2.8e-107 358.7 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 OWF39451.1 - 1.1e-114 383.1 0.1 1.3e-114 382.8 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase An_peroxidase PF03098.15 OWF39452.1 - 4.1e-181 603.2 0.0 4.8e-181 602.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase SGL PF08450.12 OWF39453.1 - 0.0003 20.5 0.0 0.006 16.2 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF39453.1 - 0.011 15.8 0.0 12 6.1 0.0 3.1 3 0 0 3 3 3 0 NHL repeat CUB PF00431.20 OWF39454.1 - 1.9e-05 25.0 0.0 0.0075 16.6 0.0 2.3 2 0 0 2 2 2 2 CUB domain TMEM154 PF15102.6 OWF39455.1 - 0.0013 18.6 10.2 0.0027 17.6 10.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family Stevor PF17410.2 OWF39455.1 - 0.038 13.6 0.2 0.046 13.3 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame cNMP_binding PF00027.29 OWF39456.1 - 2.9e-13 49.7 0.0 1.7e-11 44.0 0.0 3.0 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain 7tm_2 PF00002.24 OWF39458.1 - 2.2e-56 190.9 22.5 4.1e-56 190.0 22.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF39458.1 - 5.8e-13 48.9 8.5 1.1e-12 48.0 8.0 1.8 2 0 0 2 2 2 1 Hormone receptor domain Gate PF07670.14 OWF39458.1 - 0.04 14.2 0.8 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Nucleoside recognition DUF4079 PF13301.6 OWF39458.1 - 0.041 14.0 3.0 0.049 13.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2721 PF11026.8 OWF39458.1 - 6.7 6.6 8.6 79 3.1 8.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) UCH_1 PF13423.6 OWF39459.1 - 2.5e-100 336.2 3.7 3.5e-100 335.7 3.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OWF39459.1 - 7.7e-23 81.8 0.0 2e-22 80.5 0.0 1.8 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 OWF39459.1 - 3.9e-09 36.4 0.7 1.2e-08 34.8 0.7 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40_like PF17005.5 OWF39459.1 - 0.046 13.0 0.1 0.26 10.6 0.1 1.9 1 1 1 2 2 2 0 WD40-like domain Spo0M PF07070.11 OWF39459.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein eIF2A PF08662.11 OWF39459.1 - 0.14 12.0 0.0 1.2 8.9 0.0 2.0 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-CCCH_2 PF14608.6 OWF39459.1 - 0.17 12.4 5.3 0.52 10.9 5.3 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger UPF0239 PF06783.11 OWF39459.1 - 5.6 7.2 6.2 15 5.8 6.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF4659 PF15558.6 OWF39462.1 - 1.5e-39 136.0 87.6 1.5e-39 136.0 87.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4659) LRR_8 PF13855.6 OWF39462.1 - 7.4e-09 35.2 0.0 0.0076 16.0 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 OWF39462.1 - 9.5e-07 28.8 0.0 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Complex1_LYR PF05347.15 OWF39465.1 - 2.9e-15 56.0 2.2 3.2e-15 55.9 2.2 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OWF39465.1 - 5.6e-06 27.0 0.7 6.5e-06 26.8 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OWF39465.1 - 0.055 14.1 0.2 0.061 13.9 0.2 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Ank_2 PF12796.7 OWF39466.1 - 5.3e-21 75.0 0.0 1.3e-11 44.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF39466.1 - 5.1e-17 61.5 1.5 0.0048 17.3 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OWF39466.1 - 8.8e-17 61.2 0.4 6e-06 26.7 0.0 4.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39466.1 - 8.8e-15 53.4 2.0 0.048 14.2 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OWF39466.1 - 5.5e-11 42.5 1.0 0.02 15.2 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF39466.1 - 5.1e-05 23.5 7.2 0.0001 22.6 7.2 1.5 1 0 0 1 1 1 1 SOCS box zf-RING_2 PF13639.6 OWF39467.1 - 1.6e-12 47.6 19.7 2.5e-09 37.3 3.9 3.6 3 0 0 3 3 2 2 Ring finger domain zf-RING_11 PF17123.5 OWF39467.1 - 5.9e-08 32.3 1.3 5.9e-08 32.3 1.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger SWIM PF04434.17 OWF39467.1 - 5e-07 29.2 1.0 1.3e-06 27.9 1.0 1.7 1 0 0 1 1 1 1 SWIM zinc finger zf-C3HC4_2 PF13923.6 OWF39467.1 - 3.4e-06 26.8 4.0 3.4e-06 26.8 4.0 4.2 3 2 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 OWF39467.1 - 3e-05 23.7 11.5 9.8e-05 22.1 11.5 2.0 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-C3HC4 PF00097.25 OWF39467.1 - 6.4e-05 22.7 2.2 6.4e-05 22.7 2.2 4.2 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF39467.1 - 6.7e-05 23.1 4.3 6.7e-05 23.1 4.3 3.7 3 0 0 3 3 2 2 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 OWF39467.1 - 0.0024 17.5 1.7 0.0024 17.5 1.7 3.7 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OWF39467.1 - 0.014 15.6 4.5 0.014 15.6 4.5 2.9 3 0 0 3 3 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OWF39467.1 - 0.014 15.4 23.6 0.039 14.0 5.2 3.1 3 0 0 3 3 3 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF39467.1 - 0.015 15.3 1.9 0.015 15.3 1.9 4.0 4 1 0 4 4 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger MgtE_N PF03448.17 OWF39468.1 - 2e-09 38.0 0.0 0.077 13.6 0.0 3.6 1 1 1 3 3 3 3 MgtE intracellular N domain DUF2007 PF09413.10 OWF39468.1 - 2.4e-09 37.2 3.1 17 5.7 0.1 8.4 2 1 6 9 9 9 1 Putative prokaryotic signal transducing protein Utp12 PF04003.12 OWF39468.1 - 9.2e-06 25.9 1.4 25 5.2 0.0 5.9 2 2 5 7 7 7 0 Dip2/Utp12 Family FmrO PF07091.11 OWF39468.1 - 4.6e-05 23.1 7.1 2.5 7.6 0.1 4.4 1 1 4 5 5 5 4 Ribosomal RNA methyltransferase (FmrO) DUF2660 PF10859.8 OWF39468.1 - 0.00014 22.3 7.3 44 4.6 0.0 8.3 1 1 11 13 13 13 0 Protein of unknown function (DUF2660) DUF4077 PF13295.6 OWF39468.1 - 0.0009 19.2 9.6 2.6 7.9 0.3 4.9 1 1 5 7 7 7 3 Domain of unknown function (DUF4077) Ca_bind_SSO6904 PF18249.1 OWF39468.1 - 0.0029 17.9 11.7 13 6.2 0.2 5.6 1 1 4 6 6 6 1 Calcium binding protein SSO6904 QSOX_Trx1 PF18108.1 OWF39468.1 - 0.0074 16.5 1.6 24 5.2 0.1 4.4 1 1 3 5 5 5 0 QSOX Trx-like domain CdhC PF03598.15 OWF39468.1 - 0.009 15.9 3.8 43 3.9 0.0 5.4 1 1 4 7 7 7 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit VIGSSK PF14773.6 OWF39468.1 - 2.1 8.5 28.9 88 3.3 0.1 11.4 3 3 10 13 13 13 0 Helicase-associated putative binding domain, C-terminal KH_1 PF00013.29 OWF39469.1 - 2.4e-66 219.4 14.3 1.2e-16 60.2 0.2 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 OWF39469.1 - 3.3e-18 65.3 5.2 0.0015 18.3 0.0 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 OWF39469.1 - 3.3e-15 55.3 8.7 3.3e-15 55.3 8.7 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1897) KH_4 PF13083.6 OWF39469.1 - 3e-09 36.6 10.7 0.019 14.9 0.3 4.9 5 0 0 5 5 5 4 KH domain KH_5 PF13184.6 OWF39469.1 - 0.0002 21.4 6.8 12 6.1 0.0 4.5 4 1 0 4 4 4 3 NusA-like KH domain TRAF_BIRC3_bd PF16673.5 OWF39470.1 - 1.1e-18 66.8 3.3 1.1e-18 66.8 3.3 2.5 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain zf-TRAF PF02176.18 OWF39470.1 - 2.3e-10 41.0 35.3 5.7e-07 30.1 8.6 3.8 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4 PF00097.25 OWF39470.1 - 7e-06 25.8 9.8 7e-06 25.8 9.8 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF39470.1 - 7.3e-06 26.0 5.9 7.3e-06 26.0 5.9 3.9 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OWF39470.1 - 3e-05 23.8 4.9 0.00012 21.9 4.5 2.4 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 OWF39470.1 - 0.00027 20.9 4.7 0.00027 20.9 4.7 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF39470.1 - 0.00046 20.0 7.8 0.00046 20.0 7.8 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF39470.1 - 0.0023 17.8 10.4 0.0023 17.8 10.4 4.8 3 1 1 4 4 2 1 zinc-RING finger domain DUF3837 PF12939.7 OWF39470.1 - 0.042 14.2 0.7 1 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Not3 PF04065.15 OWF39470.1 - 0.76 9.2 8.1 0.56 9.6 1.9 2.4 1 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DHR10 PF18595.1 OWF39470.1 - 0.82 9.7 10.6 0.18 11.9 4.8 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CC2-LZ PF16516.5 OWF39470.1 - 1.3 9.4 6.2 1.5 9.2 0.6 2.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CENP-Q PF13094.6 OWF39470.1 - 4 7.6 7.4 0.42 10.8 2.6 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMCO5 PF14992.6 OWF39470.1 - 4.2 6.8 10.0 3.1 7.3 8.1 1.6 1 1 1 2 2 2 0 TMCO5 family Tropomyosin_1 PF12718.7 OWF39470.1 - 8.6 6.5 10.2 37 4.5 9.3 2.2 1 1 1 2 2 2 0 Tropomyosin like VPS9 PF02204.18 OWF39471.1 - 2e-26 92.2 0.3 8.7e-26 90.2 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 OWF39471.1 - 9.9e-19 67.9 0.0 4.2e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF5601 PF18151.1 OWF39471.1 - 1.3e-11 44.6 2.1 1.3e-11 44.6 2.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5601) Ribosomal_S6 PF01250.17 OWF39471.1 - 0.059 13.6 0.6 1.8 8.9 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein S6 Activin_recp PF01064.23 OWF39472.1 - 0.013 16.6 12.2 0.013 16.6 12.2 3.7 2 1 0 2 2 2 0 Activin types I and II receptor domain TFIIA PF03153.13 OWF39472.1 - 2.6 8.0 10.0 3.2 7.6 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ShK PF01549.24 OWF39473.1 - 1.2e-06 29.0 25.6 2.3e-05 24.8 9.7 5.5 5 0 0 5 5 5 3 ShK domain-like Fascin PF06268.13 OWF39474.1 - 0.0016 18.6 0.4 0.0039 17.4 0.4 1.6 1 0 0 1 1 1 1 Fascin domain VKOR PF07884.14 OWF39475.1 - 0.014 15.6 0.4 0.014 15.6 0.4 1.7 2 0 0 2 2 2 0 Vitamin K epoxide reductase family ShK PF01549.24 OWF39477.1 - 0.0072 16.8 6.5 0.0072 16.8 6.5 5.5 5 1 0 5 5 5 2 ShK domain-like ShK PF01549.24 OWF39478.1 - 4e-09 36.9 54.5 2e-05 25.1 9.0 9.5 8 2 1 9 9 9 4 ShK domain-like Acyl_transf_3 PF01757.22 OWF39479.1 - 3.4e-12 46.1 17.6 6.7e-12 45.1 17.6 1.5 1 0 0 1 1 1 1 Acyltransferase family EGF PF00008.27 OWF39480.1 - 3.2e-195 631.6 633.6 8.8e-09 35.5 7.8 42.6 42 0 0 42 42 42 40 EGF-like domain hEGF PF12661.7 OWF39480.1 - 4.5e-113 366.5 544.0 4.1e-06 27.2 7.0 44.6 42 0 0 42 42 42 39 Human growth factor-like EGF Laminin_G_2 PF02210.24 OWF39480.1 - 5e-31 107.9 0.9 2.6e-09 37.7 0.1 3.4 3 0 0 3 3 3 3 Laminin G domain EGF_CA PF07645.15 OWF39480.1 - 2.1e-28 98.3 629.2 1.2e-05 25.5 8.4 42.0 23 11 19 42 42 42 21 Calcium-binding EGF domain Laminin_G_1 PF00054.23 OWF39480.1 - 2.4e-25 89.2 0.0 2.5e-08 34.2 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain EGF_2 PF07974.13 OWF39480.1 - 4.5e-06 26.9 709.5 0.0045 17.3 6.5 42.5 41 1 1 42 42 42 27 EGF-like domain EGF_MSP1_1 PF12946.7 OWF39480.1 - 0.00021 21.2 5.3 0.00021 21.2 5.3 33.2 36 0 0 36 36 36 7 MSP1 EGF domain 1 cEGF PF12662.7 OWF39480.1 - 0.00045 20.1 2.3 0.00045 20.1 2.3 37.5 36 0 0 36 36 36 11 Complement Clr-like EGF-like EGF_3 PF12947.7 OWF39480.1 - 0.00045 20.3 20.6 0.001 19.2 4.8 42.7 42 1 1 43 43 43 17 EGF domain Cg6151-P PF10233.9 OWF39481.1 - 8.7e-21 74.4 1.6 1.1e-20 74.0 1.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Herpes_LMP2 PF07415.11 OWF39481.1 - 0.081 11.7 1.5 0.1 11.3 1.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein HRG PF16954.5 OWF39481.1 - 5.1 7.6 6.9 61 4.1 6.9 2.2 1 1 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Hexapep PF00132.24 OWF39482.1 - 1.7e-05 24.3 22.8 0.047 13.4 1.8 4.9 3 2 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OWF39482.1 - 0.042 13.6 0.8 0.042 13.6 0.8 3.6 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Acetyltransf_16 PF05301.11 OWF39483.1 - 4.6e-68 228.4 0.1 6.1e-68 228.0 0.1 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 OWF39483.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MMR_HSR1 PF01926.23 OWF39484.1 - 1e-14 54.6 0.0 6.6e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF39484.1 - 2.1e-06 27.3 0.1 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF39484.1 - 5.7e-05 23.1 0.1 0.0044 17.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OWF39484.1 - 0.05 13.7 2.7 0.06 13.4 0.4 2.4 2 1 1 3 3 3 0 Dynamin family DUF4602 PF15375.6 OWF39485.1 - 2.1e-13 50.7 39.0 2.1e-13 50.7 39.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4602) VWA PF00092.28 OWF39486.1 - 9.4e-35 120.4 0.1 1.7e-34 119.6 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF39486.1 - 2.7e-14 53.7 0.0 1.3e-13 51.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF39486.1 - 1.1e-06 28.7 0.0 3.7e-06 27.0 0.0 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain IQ PF00612.27 OWF39486.1 - 0.0002 20.9 1.5 0.0014 18.2 0.2 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif OLF PF02191.16 OWF39486.1 - 0.061 12.9 0.2 0.061 12.9 0.2 1.7 2 0 0 2 2 2 0 Olfactomedin-like domain BAR PF03114.18 OWF39487.1 - 9e-71 238.3 10.5 1e-70 238.1 10.5 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 OWF39487.1 - 9.8e-08 31.5 3.8 1.1e-07 31.3 2.1 1.8 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 OWF39487.1 - 0.00011 22.1 7.1 0.0023 17.7 6.2 2.4 1 1 0 1 1 1 1 BAR domain of APPL family IMD PF08397.11 OWF39487.1 - 0.0014 18.0 0.7 0.0014 18.0 0.7 2.0 1 1 1 2 2 2 1 IRSp53/MIM homology domain RNA_pol_Rpc4 PF05132.14 OWF39487.1 - 0.042 14.3 1.2 0.086 13.3 0.1 1.9 1 1 1 2 2 2 0 RNA polymerase III RPC4 DUF2783 PF10932.8 OWF39487.1 - 0.086 12.5 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) ORF45 PF17620.2 OWF39489.1 - 0.064 13.4 0.0 72 3.4 0.0 4.1 1 1 0 3 3 3 0 Family of unknown function Glycogen_syn PF05693.13 OWF39489.1 - 2.3 6.7 5.3 17 3.8 0.0 4.0 1 1 1 4 4 4 0 Glycogen synthase RNA_pol_Rpb1_R PF05001.13 OWF39489.1 - 5.3 7.6 0.0 5.3 7.6 0.0 10.4 12 4 0 12 12 12 0 RNA polymerase Rpb1 C-terminal repeat Hexapep_2 PF14602.6 OWF39489.1 - 7.6 6.4 8.7 5.8 6.8 0.0 5.3 7 0 0 7 7 7 0 Hexapeptide repeat of succinyl-transferase GlcNAc PF11397.8 OWF39490.1 - 0.00012 21.7 10.6 4.1 6.8 0.0 5.9 2 2 6 8 8 8 6 Glycosyltransferase (GlcNAc) WW PF00397.26 OWF39492.1 - 0.22 11.7 3.0 0.67 10.1 3.0 1.8 1 0 0 1 1 1 0 WW domain NPDC1 PF06809.11 OWF39493.1 - 4.8e-40 137.6 0.1 5.9e-40 137.4 0.1 1.2 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) EBV-NA3 PF05009.12 OWF39493.1 - 0.13 11.8 0.6 0.29 10.6 0.6 1.6 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nup188 PF10487.9 OWF39494.1 - 2.4e-175 585.1 1.3 2.4e-175 585.1 1.3 1.6 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Sep15_SelM PF08806.11 OWF39495.1 - 9.7e-17 60.9 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Sep15/SelM redox domain DUF2738 PF10927.8 OWF39495.1 - 0.11 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) fn3 PF00041.21 OWF39496.1 - 2.3e-25 88.8 0.5 5.9e-08 32.9 0.0 4.7 3 2 0 3 3 3 3 Fibronectin type III domain fn3_2 PF16893.5 OWF39496.1 - 1e-07 32.0 0.0 0.0066 16.6 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF39496.1 - 5.3e-05 23.7 1.0 0.45 11.1 0.0 4.3 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain HEAT_EZ PF13513.6 OWF39496.1 - 0.00024 21.6 1.5 0.02 15.4 0.1 4.1 3 1 1 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 OWF39496.1 - 0.00031 21.1 4.6 0.22 11.9 0.1 4.5 3 2 2 5 5 5 2 HEAT repeats AKAP7_RIRII_bdg PF10470.9 OWF39496.1 - 0.046 13.8 0.1 13 5.9 0.0 3.1 3 0 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Proteasom_PSMB PF10508.9 OWF39496.1 - 0.16 10.5 0.1 2.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit VWD PF00094.25 OWF39497.1 - 0.00012 22.4 0.2 0.0004 20.7 0.2 2.1 1 1 0 1 1 1 1 von Willebrand factor type D domain EGF_Tenascin PF18720.1 OWF39497.1 - 0.00014 21.8 7.5 0.00014 21.8 7.5 3.1 3 0 0 3 3 3 1 Tenascin EGF domain EGF_Tenascin PF18720.1 OWF39498.1 - 5.3e-06 26.3 7.7 5.3e-06 26.3 7.7 3.1 2 0 0 2 2 2 1 Tenascin EGF domain VWD PF00094.25 OWF39498.1 - 1.4e-05 25.4 1.4 2.6e-05 24.5 0.2 2.2 2 1 0 2 2 2 1 von Willebrand factor type D domain EGF_2 PF07974.13 OWF39498.1 - 0.0026 18.1 15.2 0.0026 18.1 15.2 4.9 5 0 0 5 5 5 1 EGF-like domain Pkinase PF00069.25 OWF39499.1 - 2e-60 204.4 0.0 2.4e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF39499.1 - 6.2e-44 150.2 0.0 7.5e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF39499.1 - 9e-09 35.0 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OWF39499.1 - 0.00031 19.9 0.2 0.00082 18.5 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OWF39499.1 - 0.0098 14.7 0.0 0.02 13.7 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OWF39499.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF39499.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Trypsin_2 PF13365.6 OWF39500.1 - 0.0043 18.0 0.0 0.0099 16.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 OWF39500.1 - 0.031 12.8 0.5 0.14 10.6 0.0 2.1 2 1 0 2 2 2 0 Peptidase family S64 7tm_1 PF00001.21 OWF39501.1 - 3.2e-22 79.1 23.7 4.5e-22 78.6 23.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF39501.1 - 5.9e-11 42.2 25.3 7.3e-11 41.9 25.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF39501.1 - 0.058 13.0 27.0 0.18 11.4 25.2 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF39501.1 - 0.97 9.1 26.6 1.3 8.7 26.6 1.1 1 0 0 1 1 1 0 Olfactory receptor Pyr_redox_2 PF07992.14 OWF39502.1 - 8.4e-55 186.1 0.3 1.3e-54 185.4 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OWF39502.1 - 1.1e-27 96.5 0.0 2.4e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glutaredoxin PF00462.24 OWF39502.1 - 1.8e-15 56.9 1.0 3.2e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 Glutaredoxin Pyr_redox PF00070.27 OWF39502.1 - 1.8e-15 57.2 6.7 3.3e-13 50.0 0.0 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF39502.1 - 2.6e-11 43.3 0.4 7e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF39502.1 - 6.5e-08 32.1 1.9 1.5e-06 27.5 0.9 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OWF39502.1 - 0.0011 18.2 0.1 0.0019 17.4 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thioredoxin_3 PF13192.6 OWF39502.1 - 0.0017 18.4 0.1 0.0056 16.7 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin domain HI0933_like PF03486.14 OWF39502.1 - 0.0019 17.0 0.2 0.0042 15.8 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OWF39502.1 - 0.0025 17.2 0.2 0.011 15.1 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OWF39502.1 - 0.006 15.9 0.3 0.015 14.6 0.3 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OWF39502.1 - 0.0068 15.8 2.7 0.0093 15.4 1.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF836 PF05768.14 OWF39502.1 - 0.019 15.3 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) NAD_binding_8 PF13450.6 OWF39502.1 - 0.058 13.6 0.7 0.15 12.3 0.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DSBA PF01323.20 OWF39502.1 - 0.11 12.3 0.2 0.33 10.7 0.1 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 OWF39502.1 - 0.12 12.9 0.1 0.32 11.5 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.16 OWF39503.1 - 2.6e-50 171.3 38.9 1.1e-43 149.5 30.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 OWF39503.1 - 0.00041 19.3 3.4 0.00041 19.3 3.4 2.1 2 0 0 2 2 2 1 POT family OATP PF03137.20 OWF39503.1 - 5.6 5.1 12.4 0.27 9.5 0.1 2.8 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ank_2 PF12796.7 OWF39504.1 - 6.3e-22 78.0 0.0 2.2e-10 41.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF39504.1 - 7.1e-20 70.5 0.2 0.0004 20.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OWF39504.1 - 1.3e-19 70.3 1.0 1.9e-08 34.7 0.0 3.6 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF39504.1 - 3.2e-19 68.8 0.3 6.7e-08 32.7 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39504.1 - 3.1e-16 57.8 0.1 0.0032 17.8 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat SOCS_box PF07525.16 OWF39504.1 - 3e-09 37.1 0.2 7.1e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 SOCS box EGF_CA PF07645.15 OWF39505.1 - 7.3e-80 262.9 286.7 1.1e-07 31.9 13.0 18.5 13 4 5 18 18 18 15 Calcium-binding EGF domain EGF PF00008.27 OWF39505.1 - 5.1e-79 260.1 266.5 2.4e-08 34.1 4.5 19.1 18 1 0 18 18 18 17 EGF-like domain hEGF PF12661.7 OWF39505.1 - 4.8e-41 138.0 255.4 5e-05 23.8 6.6 21.3 22 0 0 22 22 22 17 Human growth factor-like EGF EGF_2 PF07974.13 OWF39505.1 - 5.5e-30 103.4 312.1 0.00013 22.2 14.1 19.5 19 0 0 19 19 19 15 EGF-like domain DSL PF01414.19 OWF39505.1 - 5.7e-19 68.2 6.9 5.7e-19 68.2 6.9 13.1 7 5 6 13 13 13 2 Delta serrate ligand EGF_3 PF12947.7 OWF39505.1 - 1.3e-12 47.7 248.7 0.0034 17.5 7.3 18.2 18 0 0 18 18 18 12 EGF domain cEGF PF12662.7 OWF39505.1 - 0.037 14.0 0.3 0.037 14.0 0.3 19.1 19 3 0 19 19 19 0 Complement Clr-like EGF-like DSL PF01414.19 OWF39506.1 - 1.7e-17 63.4 7.9 1.7e-17 63.4 7.9 3.9 3 0 0 3 3 3 2 Delta serrate ligand EGF PF00008.27 OWF39506.1 - 2.1e-12 47.1 52.7 2.8e-05 24.3 6.4 5.3 4 1 0 4 4 4 3 EGF-like domain MNNL PF07657.13 OWF39506.1 - 1e-08 35.1 1.7 1e-08 35.1 1.7 3.0 3 2 1 4 4 4 1 N terminus of Notch ligand hEGF PF12661.7 OWF39506.1 - 0.022 15.4 7.3 0.022 15.4 7.3 7.2 7 1 0 7 7 7 0 Human growth factor-like EGF cEGF PF12662.7 OWF39506.1 - 0.039 13.9 0.8 0.039 13.9 0.8 5.2 5 0 0 5 5 5 0 Complement Clr-like EGF-like SCIMP PF15050.6 OWF39506.1 - 0.051 14.0 1.5 0.071 13.6 0.1 1.9 2 0 0 2 2 2 0 SCIMP protein EGF_CA PF07645.15 OWF39506.1 - 0.19 12.0 56.8 0.082 13.1 8.0 4.9 2 1 3 5 5 5 0 Calcium-binding EGF domain EGF_3 PF12947.7 OWF39506.1 - 0.23 11.7 45.0 1.1 9.5 6.5 4.8 4 0 0 4 4 4 0 EGF domain EphA2_TM PF14575.6 OWF39506.1 - 0.33 11.9 2.1 0.7 10.8 0.1 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UPF0370 PF13980.6 OWF39506.1 - 1.6 8.8 4.3 0.75 9.9 1.7 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) S-methyl_trans PF02574.16 OWF39507.1 - 2.8e-20 73.2 0.1 3.7e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase S-methyl_trans PF02574.16 OWF39508.1 - 1.6e-36 126.5 0.0 2e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase KH_9 PF17904.1 OWF39508.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 FMRP KH0 domain AP_endonuc_2 PF01261.24 OWF39508.1 - 0.11 12.0 0.0 13 5.2 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel PhyH PF05721.13 OWF39509.1 - 3e-47 161.6 0.0 4.1e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OWF39509.1 - 0.00015 20.7 0.1 0.039 12.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Zn_ribbon_2 PF12674.7 OWF39509.1 - 0.075 13.7 0.1 0.2 12.4 0.1 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain BTB PF00651.31 OWF39510.1 - 3.1e-11 43.5 0.6 3.1e-11 43.5 0.6 1.6 2 0 0 2 2 2 1 BTB/POZ domain Complex1_49kDa PF00346.19 OWF39510.1 - 0.087 11.9 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Glyco_hydro_20 PF00728.22 OWF39511.1 - 1.1e-100 337.4 0.5 1.5e-100 337.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 OWF39511.1 - 1.6e-31 109.1 0.0 3.3e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 OWF39511.1 - 8.6e-22 76.9 0.0 6.3e-21 74.1 0.0 2.3 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 OWF39511.1 - 6.1e-11 43.2 0.0 1.9e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 BNR PF02012.20 OWF39511.1 - 0.16 12.0 1.9 0.71 10.1 1.9 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat DSPc PF00782.20 OWF39512.1 - 6.5e-14 51.9 1.1 4.4e-12 46.0 0.1 3.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF39512.1 - 1.9e-09 37.5 0.3 4.3e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF39512.1 - 0.0028 17.7 0.1 0.0095 15.9 0.0 1.9 2 1 0 2 2 2 1 Tyrosine phosphatase family CDKN3 PF05706.12 OWF39512.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 OWF39512.1 - 0.099 12.8 0.1 0.76 9.9 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate ADH_N_2 PF16884.5 OWF39513.1 - 2.8e-28 98.0 0.2 6.6e-28 96.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OWF39513.1 - 1.6e-18 67.0 0.0 2.5e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF39513.1 - 4.1e-05 24.6 0.0 0.00017 22.6 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1772 PF08592.11 OWF39514.1 - 3.1e-13 50.2 0.1 4.4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ATP-synt_I PF03899.15 OWF39514.1 - 0.03 14.7 0.6 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 ATP synthase I chain DUF1772 PF08592.11 OWF39515.1 - 2.1e-19 70.2 0.1 2.6e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1772 PF08592.11 OWF39516.1 - 9.4e-17 61.6 0.1 1.1e-16 61.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ADP_ribosyl_GH PF03747.14 OWF39517.1 - 1.9e-58 198.5 0.1 2.7e-58 198.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase ADP_ribosyl_GH PF03747.14 OWF39518.1 - 2.8e-59 201.2 0.1 3.6e-59 200.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase GAPT PF11770.8 OWF39519.1 - 0.0025 17.7 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) WBP-1 PF11669.8 OWF39519.1 - 0.29 11.8 7.1 3.6 8.3 7.1 2.2 1 1 0 1 1 1 0 WW domain-binding protein 1 Cyclin_N PF00134.23 OWF39520.1 - 2.9e-12 46.4 0.2 4.7e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF39520.1 - 0.0048 17.0 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 OWF39520.1 - 0.0052 16.8 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat SEFIR PF08357.11 OWF39523.1 - 3e-26 92.5 0.1 5.5e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 SEFIR domain Imm42 PF15593.6 OWF39523.1 - 0.054 14.0 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 42 Cellulose_synt PF03552.14 OWF39524.1 - 0.19 10.2 0.9 0.29 9.6 0.9 1.2 1 0 0 1 1 1 0 Cellulose synthase FtsK_SpoIIIE_N PF12538.8 OWF39524.1 - 0.22 11.8 4.0 0.12 12.6 0.8 2.2 2 0 0 2 2 2 0 DNA transporter RPN13_C PF16550.5 OWF39525.1 - 2.9e-34 117.6 2.4 5.2e-34 116.8 2.4 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 OWF39525.1 - 3.4e-33 114.0 0.7 5.4e-33 113.4 0.7 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ASXH PF13919.6 OWF39525.1 - 0.033 14.2 0.1 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 Asx homology domain SOG2 PF10428.9 OWF39525.1 - 1.9 7.6 7.6 2.7 7.1 7.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein dsrm PF00035.26 OWF39526.1 - 3.9e-40 136.4 6.9 3.8e-11 43.5 0.6 5.2 5 0 0 5 5 5 4 Double-stranded RNA binding motif Staufen_C PF16482.5 OWF39526.1 - 1.2e-10 41.5 0.1 1.1e-07 32.0 0.0 4.3 5 0 0 5 5 5 1 Staufen C-terminal domain DND1_DSRM PF14709.7 OWF39526.1 - 0.059 13.6 11.3 1.2 9.4 0.1 5.2 5 2 0 5 5 5 0 double strand RNA binding domain from DEAD END PROTEIN 1 F-box PF00646.33 OWF39527.1 - 3.3e-08 33.2 4.6 7.1e-08 32.1 4.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OWF39527.1 - 3.7e-08 33.1 5.5 6.9e-08 32.3 5.5 1.5 1 0 0 1 1 1 1 F-box-like DUF4508 PF14969.6 OWF39527.1 - 0.0047 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Glyco_hydro_30 PF02055.16 OWF39527.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain EF-hand_7 PF13499.6 OWF39528.1 - 8.5e-34 115.8 6.2 8.3e-17 61.4 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF39528.1 - 1.2e-29 99.6 16.0 6.6e-08 31.6 0.3 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 OWF39528.1 - 8.2e-27 90.8 6.7 2e-08 33.5 0.3 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OWF39528.1 - 3.9e-22 77.9 5.8 1.2e-11 44.3 0.3 3.5 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF39528.1 - 8.8e-22 75.6 14.0 1.2e-07 30.9 0.7 5.0 4 2 2 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.9 OWF39528.1 - 3.6e-10 40.2 0.5 4.5e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF39528.1 - 1.3e-07 31.7 0.0 0.029 14.5 0.0 3.3 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_9 PF14658.6 OWF39528.1 - 2.3e-06 27.8 0.1 0.086 13.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF39528.1 - 4.7e-05 23.3 1.8 0.072 13.1 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 OWF39528.1 - 0.00058 19.8 0.8 0.79 9.7 0.0 2.5 1 1 2 3 3 3 2 Tellurite resistance protein TerB EF-hand_11 PF08976.11 OWF39528.1 - 0.0084 17.0 0.2 1.8 9.5 0.0 2.5 1 1 2 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 OWF39528.1 - 0.044 13.6 0.2 0.044 13.6 0.2 2.1 2 1 1 3 3 3 0 EF hand RST PF12174.8 OWF39528.1 - 0.053 13.4 0.8 0.41 10.6 0.1 2.6 3 1 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain PMBR PF09373.10 OWF39528.1 - 0.1 12.8 0.4 6.2 7.2 0.0 3.6 5 0 0 5 5 5 0 Pseudomurein-binding repeat EF-hand_7 PF13499.6 OWF39529.1 - 6.7e-29 100.2 0.8 1.1e-15 57.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF39529.1 - 1.1e-28 96.5 6.5 8.2e-08 31.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF39529.1 - 3.1e-25 85.9 0.9 2e-08 33.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF39529.1 - 1.1e-21 75.3 3.2 5.2e-07 28.9 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF39529.1 - 4.5e-17 61.6 3.2 5.9e-09 35.7 0.3 3.5 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF39529.1 - 3.2e-11 43.5 0.2 3e-05 24.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF39529.1 - 3.8e-07 30.0 0.3 0.023 14.6 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OWF39529.1 - 6.6e-07 29.4 4.5 0.005 17.0 0.2 3.6 1 1 3 4 4 4 3 Dockerin type I domain EF-hand_9 PF14658.6 OWF39529.1 - 5e-06 26.8 0.1 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 OWF39529.1 - 0.0019 19.1 0.0 0.012 16.5 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 OWF39529.1 - 0.0036 17.2 0.1 1.5 8.7 0.0 2.5 2 1 1 3 3 3 2 Tellurite resistance protein TerB EF-hand_13 PF17958.1 OWF39529.1 - 0.01 15.6 0.0 3.1 7.7 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain EFhand_Ca_insen PF08726.10 OWF39529.1 - 0.034 14.2 0.5 0.08 13.0 0.1 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand VCBS PF13517.6 OWF39529.1 - 1.2 9.8 6.7 3.9 8.1 1.0 3.1 2 2 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-BED PF02892.15 OWF39530.1 - 0.21 11.7 1.2 0.38 10.8 0.3 1.9 2 0 0 2 2 2 0 BED zinc finger Ank_4 PF13637.6 OWF39531.1 - 1.9e-19 69.8 0.8 1.2e-07 32.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39531.1 - 2.6e-15 55.0 0.0 8.4e-05 22.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OWF39531.1 - 5.2e-15 55.1 0.0 2.4e-06 27.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OWF39531.1 - 5.5e-15 55.7 0.0 6.7e-11 42.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF39531.1 - 2.2e-09 37.4 0.0 3.2e-06 27.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39532.1 - 5e-10 38.8 0.0 0.0004 20.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OWF39532.1 - 1.3e-09 38.5 0.0 1.5e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF39532.1 - 2.4e-09 37.3 0.0 2.8e-06 27.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF39532.1 - 7.9e-09 35.6 0.1 0.00027 21.2 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OWF39532.1 - 4.3e-08 33.5 0.0 3.1e-07 30.8 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) GATase_7 PF13537.6 OWF39532.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase domain FAM47 PF14642.6 OWF39534.1 - 0.0023 17.6 33.0 0.015 14.9 6.9 4.1 1 1 3 4 4 4 3 FAM47 family DUF756 PF05506.12 OWF39534.1 - 0.01 16.8 0.2 4.9 8.1 0.2 3.9 1 1 0 1 1 1 0 Domain of unknown function (DUF756) TOBE PF03459.17 OWF39534.1 - 0.38 11.1 11.1 39 4.6 0.1 6.8 3 2 4 9 9 9 0 TOBE domain Glyco_transf_10 PF00852.19 OWF39536.1 - 8.8e-44 149.3 2.1 1.3e-43 148.7 2.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF39536.1 - 1.4e-22 80.2 0.2 1.4e-22 80.2 0.2 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Cupin_8 PF13621.6 OWF39537.1 - 1.2e-26 94.0 1.5 1.3e-25 90.5 1.5 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OWF39537.1 - 4.6e-05 23.0 0.1 9.4e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OWF39537.1 - 0.019 15.4 0.5 0.046 14.2 0.0 1.9 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 OWF39537.1 - 0.028 14.1 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Cupin domain Atypical_Card PF18461.1 OWF39538.1 - 0.019 15.2 0.1 0.043 14.0 0.1 1.6 1 0 0 1 1 1 0 Atypical caspase recruitment domain CRAL_TRIO PF00650.20 OWF39539.1 - 9.3e-34 116.4 0.0 1.5e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OWF39539.1 - 3.9e-07 30.3 0.0 1.9e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OWF39539.1 - 5.1e-07 29.8 1.6 1.4e-06 28.4 1.6 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Trm5_N PF18093.1 OWF39539.1 - 0.11 12.4 0.3 0.25 11.3 0.3 1.6 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain CRAL_TRIO PF00650.20 OWF39540.1 - 5.9e-34 117.1 0.0 8.5e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OWF39540.1 - 3.8e-08 33.6 0.0 5.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OWF39540.1 - 0.00017 21.7 0.2 0.00051 20.2 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Filament PF00038.21 OWF39541.1 - 0.39 10.2 9.6 1.3 8.5 2.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein Sec8_exocyst PF04048.14 OWF39541.1 - 0.94 9.4 10.3 5.5 6.9 2.6 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain LXG PF04740.12 OWF39541.1 - 3 7.5 17.1 4.8 6.8 7.6 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily SnoaL_3 PF13474.6 OWF39542.1 - 0.0058 16.9 6.3 15 5.9 0.7 4.6 1 1 3 4 4 4 3 SnoaL-like domain DUF2689 PF10894.8 OWF39542.1 - 0.0067 16.2 10.0 32 4.4 0.1 6.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2689) zf-C2H2_2 PF12756.7 OWF39542.1 - 0.015 15.6 5.1 0.1 12.9 1.9 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF745 PF05335.13 OWF39542.1 - 0.15 11.8 4.5 0.35 10.6 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Psu PF07455.11 OWF39542.1 - 0.42 10.2 8.5 22 4.6 0.2 4.2 1 1 2 3 3 3 0 Phage polarity suppression protein (Psu) DUF4878 PF12870.7 OWF39542.1 - 0.91 9.9 14.5 3.2 8.1 0.5 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4878) Il2rg PF15874.5 OWF39542.1 - 2.2 8.6 9.1 4.1 7.7 0.3 3.6 1 1 2 3 3 3 0 Putative Interleukin 2 receptor, gamma chain Ribosomal_S8e PF01201.22 OWF39542.1 - 6.3 7.0 8.3 8.5 6.6 2.2 2.5 1 1 1 2 2 2 0 Ribosomal protein S8e SAM_DrpA PF18255.1 OWF39543.1 - 0.013 15.7 0.5 37 4.7 0.0 4.3 4 1 0 4 4 4 0 DNA processing protein A sterile alpha motif domain PCRF PF03462.18 OWF39543.1 - 0.26 11.1 2.2 3 7.7 0.2 2.7 2 1 1 3 3 3 0 PCRF domain FAM167 PF11652.8 OWF39544.1 - 1.9e-13 50.7 0.7 4.3e-13 49.6 0.7 1.6 1 0 0 1 1 1 1 FAM167 Ras PF00071.22 OWF39545.1 - 8.7e-42 142.5 0.0 1.1e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF39545.1 - 4.1e-28 98.0 0.1 5.8e-28 97.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF39545.1 - 1.5e-11 44.1 0.1 1.7e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF39545.1 - 9.9e-07 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF39545.1 - 5.2e-05 22.9 0.1 0.0015 18.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DLIC PF05783.11 OWF39545.1 - 0.00019 20.4 0.1 0.27 10.0 0.1 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_7 PF12775.7 OWF39545.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 OWF39545.1 - 0.0017 18.6 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OWF39545.1 - 0.0018 18.0 0.1 0.14 11.9 0.1 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OWF39545.1 - 0.0018 18.1 0.0 0.28 10.9 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OWF39545.1 - 0.0046 17.0 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 OWF39545.1 - 0.0091 15.4 0.0 0.055 12.9 0.0 2.0 1 1 1 2 2 2 1 Bacterial TniB protein DUF815 PF05673.13 OWF39545.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1_Xtn PF16897.5 OWF39545.1 - 0.034 14.2 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TsaE PF02367.17 OWF39545.1 - 0.035 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OWF39545.1 - 0.04 13.7 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OWF39545.1 - 0.044 13.8 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 OWF39545.1 - 0.045 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 OWF39545.1 - 0.047 12.8 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 OWF39545.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 OWF39545.1 - 0.081 12.5 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OWF39545.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 OWF39545.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.6 OWF39545.1 - 0.14 10.9 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OWF39545.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sulfotransfer_1 PF00685.27 OWF39546.1 - 2e-10 40.6 0.2 6.7e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF39546.1 - 0.00055 20.4 0.3 0.033 14.6 0.1 3.3 2 1 0 2 2 2 1 Sulfotransferase family HH_signal PF01085.18 OWF39546.1 - 0.014 15.0 0.3 0.023 14.4 0.3 1.3 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Ank_2 PF12796.7 OWF39549.1 - 3.7e-34 117.2 1.6 3.8e-15 56.2 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39549.1 - 9.8e-27 93.0 0.0 2.9e-09 37.3 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF39549.1 - 1.9e-23 82.2 1.5 7e-10 39.0 0.1 3.9 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39549.1 - 8.9e-21 71.8 0.0 4e-05 23.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OWF39549.1 - 4.7e-19 67.9 1.8 5.4e-06 26.6 0.0 5.8 5 1 0 5 5 5 3 Ankyrin repeat PH PF00169.29 OWF39549.1 - 0.00053 20.5 0.0 0.0014 19.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Oxysterol_BP PF01237.18 OWF39550.1 - 9.9e-141 468.9 0.0 1.1e-140 468.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kelch_3 PF13415.6 OWF39551.1 - 2.4e-19 69.1 4.3 9.3e-06 25.8 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF39551.1 - 3.1e-15 55.7 2.3 0.0018 18.2 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OWF39551.1 - 7.4e-15 54.7 8.1 0.0027 17.7 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF39551.1 - 2.6e-10 39.9 7.2 0.0028 17.6 0.1 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OWF39551.1 - 3.3e-09 36.2 3.6 0.00082 18.9 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OWF39551.1 - 2.6e-08 33.9 3.8 0.11 12.8 0.0 4.6 3 1 1 4 4 4 2 Kelch motif Myosin_head PF00063.21 OWF39552.1 - 8.3e-195 648.9 0.0 1.3e-194 648.2 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) MH2 PF03166.14 OWF39552.1 - 2.6e-24 86.5 0.0 5.6e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 MH2 domain AAA_22 PF13401.6 OWF39552.1 - 0.0072 16.6 0.0 0.054 13.8 0.0 2.6 1 0 0 1 1 1 1 AAA domain IQ PF00612.27 OWF39552.1 - 0.047 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif DEAD PF00270.29 OWF39552.1 - 0.091 12.5 0.0 0.41 10.4 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OWF39552.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PMP22_Claudin PF00822.20 OWF39553.1 - 6.1e-06 26.2 18.3 1.8e-05 24.7 18.3 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family gpUL132 PF11359.8 OWF39553.1 - 0.077 12.5 1.5 0.097 12.2 1.5 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Claudin_2 PF13903.6 OWF39553.1 - 0.17 11.6 30.6 1.5 8.5 3.2 3.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Lectin_C PF00059.21 OWF39554.1 - 7e-20 71.8 0.3 7e-20 71.8 0.3 1.5 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 OWF39554.1 - 0.0041 16.8 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Mut7-C PF01927.16 OWF39555.1 - 2.2e-25 89.4 3.1 1.7e-16 60.6 0.4 3.0 3 0 0 3 3 3 2 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 OWF39555.1 - 3e-19 69.4 0.0 7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease MIS13 PF08202.11 OWF39556.1 - 2.9e-11 43.2 7.6 3.8e-09 36.3 1.9 2.2 1 1 1 2 2 2 2 Mis12-Mtw1 protein family DUF1635 PF07795.11 OWF39556.1 - 0.00023 21.1 0.2 0.00045 20.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) HTH_12 PF08461.10 OWF39556.1 - 0.023 14.6 0.1 1.4 8.9 0.0 3.0 2 1 1 3 3 3 0 Ribonuclease R winged-helix domain GrpE PF01025.19 OWF39556.1 - 0.29 10.8 7.2 3.1 7.5 0.4 2.3 2 0 0 2 2 2 0 GrpE DUF2464 PF10240.9 OWF39557.1 - 2.6e-74 250.0 0.0 3e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 AA_permease_2 PF13520.6 OWF39558.1 - 6.1e-57 193.3 40.9 7.4e-57 193.1 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF39558.1 - 4.4e-32 111.3 39.4 6.2e-32 110.8 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease Orf78 PF06024.12 OWF39558.1 - 2.6 8.4 6.1 16 5.9 0.1 3.5 3 0 0 3 3 3 0 Orf78 (ac78) TRH PF05438.12 OWF39559.1 - 3.5e-06 26.9 0.3 0.013 15.3 0.0 2.4 1 1 1 2 2 2 2 Thyrotropin-releasing hormone (TRH) eIF-3_zeta PF05091.12 OWF39559.1 - 0.1 11.6 0.1 29 3.5 0.0 2.8 1 1 2 4 4 4 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RAD51_interact PF15696.5 OWF39559.1 - 0.13 12.3 19.2 36 4.5 0.6 6.9 3 3 4 7 7 7 0 RAD51 interacting motif HDA2-3 PF11496.8 OWF39559.1 - 0.81 8.8 9.8 7.5e+02 -1.0 9.8 3.3 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 LIM PF00412.22 OWF39561.1 - 9e-32 109.1 15.7 4.7e-17 62.0 1.7 2.2 2 0 0 2 2 2 2 LIM domain zf-dskA_traR PF01258.17 OWF39561.1 - 0.41 10.6 0.1 0.41 10.6 0.1 3.8 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zf_UBZ PF18439.1 OWF39561.1 - 0.64 9.7 0.1 0.64 9.7 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HTH_ParB PF17762.1 OWF39562.1 - 0.00013 21.7 0.0 0.73 9.7 0.0 3.3 4 0 0 4 4 4 2 HTH domain found in ParB protein Tcp10_C PF07202.13 OWF39562.1 - 0.0023 17.9 0.0 0.12 12.4 0.0 1.9 1 1 1 2 2 2 2 T-complex protein 10 C-terminus DUF1609 PF07753.11 OWF39562.1 - 0.22 11.0 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1609) Pkinase PF00069.25 OWF39562.1 - 1.2 8.4 5.4 29 3.9 0.1 3.4 1 1 2 3 3 3 0 Protein kinase domain Tektin PF03148.14 OWF39564.1 - 7.9e-37 126.9 5.1 1.1e-36 126.4 5.1 1.2 1 0 0 1 1 1 1 Tektin family Vps51 PF08700.11 OWF39564.1 - 0.036 14.1 1.6 0.14 12.3 0.1 2.5 2 0 0 2 2 2 0 Vps51/Vps67 DUF948 PF06103.11 OWF39564.1 - 0.06 13.6 1.0 15 6.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 OWF39564.1 - 0.51 9.6 13.6 0.28 10.5 6.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SAM_Exu PF18609.1 OWF39564.1 - 0.54 10.4 4.8 0.19 11.8 0.4 2.4 2 0 0 2 2 2 0 Exuperantia SAM-like domain Prefoldin_2 PF01920.20 OWF39564.1 - 0.56 10.2 6.9 5.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Prefoldin subunit Snf7 PF03357.21 OWF39564.1 - 0.78 9.3 5.6 0.3 10.7 2.8 1.8 2 0 0 2 2 2 0 Snf7 DUF5320 PF17253.2 OWF39564.1 - 1.8 9.7 5.0 25 6.0 0.3 3.1 4 0 0 4 4 3 0 Family of unknown function (DUF5320) Cep57_CLD_2 PF14197.6 OWF39564.1 - 2.7 8.2 18.4 0.072 13.2 3.5 4.0 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF745 PF05335.13 OWF39564.1 - 3 7.5 11.5 1.5 8.5 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF745) OmpH PF03938.14 OWF39564.1 - 3.4 8.0 6.3 0.73 10.2 1.3 2.2 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.6 OWF39564.1 - 3.7 7.7 16.7 0.05 13.8 4.5 3.0 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit GrpE PF01025.19 OWF39564.1 - 5.5 6.6 8.0 1.2 8.8 0.1 2.7 2 1 0 2 2 2 0 GrpE Fez1 PF06818.15 OWF39564.1 - 7.8 6.9 12.1 0.98 9.8 1.1 2.9 1 1 2 3 3 3 0 Fez1 Ras PF00071.22 OWF39565.1 - 1.5e-60 203.5 0.1 1.8e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF39565.1 - 6.8e-32 110.2 0.0 1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF39565.1 - 8.3e-13 48.2 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF39565.1 - 4.9e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF39565.1 - 0.00011 21.9 0.0 0.0042 16.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF39565.1 - 0.00041 20.3 0.1 0.83 9.5 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OWF39565.1 - 0.0012 18.3 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OWF39565.1 - 0.049 13.4 0.0 1.2 8.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OWF39565.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 OWF39565.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 OWF39565.1 - 0.1 12.3 0.1 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain FAD_binding_5 PF00941.21 OWF39566.1 - 0.011 15.5 1.0 0.068 12.9 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain in molybdopterin dehydrogenase DUF2797 PF10977.8 OWF39566.1 - 8 6.3 10.3 12 5.7 6.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) NuiA PF07924.11 OWF39566.1 - 8.5 6.8 10.3 0.78 10.1 2.3 2.9 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein FAD_binding_5 PF00941.21 OWF39567.1 - 0.011 15.5 1.0 0.068 12.9 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain in molybdopterin dehydrogenase DUF2797 PF10977.8 OWF39567.1 - 8 6.3 10.3 12 5.7 6.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) NuiA PF07924.11 OWF39567.1 - 8.5 6.8 10.3 0.78 10.1 2.3 2.9 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein ubiquitin PF00240.23 OWF39569.1 - 7.5e-09 35.2 0.1 1.2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OWF39569.1 - 1.5e-05 24.7 0.1 2.7e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OWF39569.1 - 0.00028 21.3 0.2 0.00042 20.7 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3944 PF13099.6 OWF39569.1 - 0.12 12.3 0.3 9.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) LRAT PF04970.13 OWF39570.1 - 3.3e-32 111.4 0.0 4.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF39570.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family MFS_1 PF07690.16 OWF39571.1 - 4.7e-16 58.7 39.8 3.9e-13 49.1 11.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF39571.1 - 1.2e-06 27.7 5.7 1.2e-06 27.7 5.7 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39572.1 - 1.2e-12 47.5 67.3 4.6e-12 45.5 35.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OWF39572.1 - 0.9 7.8 21.8 1.1 7.4 2.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 OWF39573.1 - 2.2e-19 69.6 10.0 2.5e-19 69.4 10.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF39574.1 - 0.069 12.1 6.7 0.081 11.8 6.7 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily LRAT PF04970.13 OWF39575.1 - 5.2e-34 117.3 0.0 6.6e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Gram_pos_anchor PF00746.21 OWF39575.1 - 0.0051 16.7 1.1 0.0051 16.7 1.1 1.8 2 0 0 2 2 2 1 LPXTG cell wall anchor motif NLPC_P60 PF00877.19 OWF39575.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family ABA_WDS PF02496.16 OWF39575.1 - 0.044 14.3 0.2 0.072 13.6 0.2 1.4 1 0 0 1 1 1 0 ABA/WDS induced protein NitrOD2 PF18550.1 OWF39575.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Nitrososphaera output domain 2 WD40 PF00400.32 OWF39576.1 - 9.7e-43 143.3 33.7 3.1e-07 31.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF39576.1 - 2.2e-14 53.5 0.2 0.0041 17.4 0.1 5.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain FapA PF03961.13 OWF39576.1 - 0.016 13.9 5.7 0.023 13.3 5.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ge1_WD40 PF16529.5 OWF39576.1 - 0.032 13.2 7.2 1.6 7.6 0.0 3.8 1 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sen15 PF09631.10 OWF39576.1 - 0.063 13.6 0.1 0.41 11.0 0.0 2.4 3 0 0 3 3 2 0 Sen15 protein Nup160 PF11715.8 OWF39576.1 - 0.088 11.4 8.4 10 4.6 0.1 4.2 2 1 1 4 4 4 0 Nucleoporin Nup120/160 V_ATPase_I PF01496.19 OWF39576.1 - 0.13 10.2 5.1 0.18 9.7 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPP PF04728.13 OWF39576.1 - 0.25 11.7 1.2 4.7 7.7 0.2 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Tho2 PF11262.8 OWF39576.1 - 1.1 8.3 8.2 1.9 7.6 8.2 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Cep57_CLD_2 PF14197.6 OWF39576.1 - 4.4 7.5 13.6 7.3 6.8 1.4 3.9 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 GPS2_interact PF15784.5 OWF39576.1 - 5 7.6 7.0 2.4 8.7 3.8 2.0 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain HTH_16 PF12645.7 OWF39577.1 - 0.63 10.1 10.2 14 5.8 0.4 5.1 3 2 3 6 6 6 0 Helix-turn-helix domain DUF1652 PF07865.11 OWF39578.1 - 0.038 13.8 16.6 2.5 8.0 0.1 6.4 1 1 8 9 9 9 0 Protein of unknown function (DUF1652) Pih1_fungal_CS PF18482.1 OWF39578.1 - 0.06 13.9 10.5 1.5 9.4 0.4 3.0 1 1 2 3 3 3 0 Fungal Pih1 CS domain DUF4179 PF13786.6 OWF39578.1 - 0.13 12.8 22.9 46 4.6 4.8 5.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) Spore-coat_CotZ PF10612.9 OWF39578.1 - 0.69 10.0 7.7 12 6.0 1.7 2.9 1 1 1 2 2 2 0 Spore coat protein Z DUF5641 PF18701.1 OWF39578.1 - 2.2 8.5 12.0 30 4.9 0.8 4.2 1 1 3 4 4 4 0 Family of unknown function (DUF5641) DUF4573 PF15140.6 OWF39579.1 - 1.4e-10 41.2 33.7 0.0084 15.9 8.5 4.9 1 1 4 5 5 5 5 Domain of unknown function (DUF4573) Glutenin_hmw PF03157.13 OWF39579.1 - 0.029 12.8 28.5 0.06 11.8 28.5 1.4 1 0 0 1 1 1 0 High molecular weight glutenin subunit Ion_trans PF00520.31 OWF39580.1 - 3.4e-27 95.2 28.7 4.8e-27 94.8 28.7 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF39580.1 - 4.8e-23 81.3 0.1 1.1e-22 80.1 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF39580.1 - 6.8e-11 42.0 12.7 6.8e-11 42.0 12.7 3.5 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 OWF39581.1 - 6.5e-28 97.6 30.1 8.7e-28 97.2 30.1 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF39581.1 - 2.4e-20 72.6 0.4 1.1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF39581.1 - 4e-10 39.5 15.4 4e-10 39.5 15.4 3.4 4 0 0 4 4 4 1 Ion channel BTB_3 PF16017.5 OWF39581.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Herpes_glycop PF01528.16 OWF39582.1 - 0.00072 18.5 7.9 0.00072 18.5 7.9 2.1 2 1 0 2 2 2 1 Herpesvirus glycoprotein M Abhydrolase_9_N PF15420.6 OWF39582.1 - 0.025 14.6 7.1 0.37 10.8 1.0 3.1 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF4426 PF14467.6 OWF39582.1 - 0.12 12.3 0.1 0.36 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) Mannosyl_trans4 PF15971.5 OWF39582.1 - 1.4 8.8 7.5 1.5 8.7 0.3 3.0 3 0 0 3 3 3 0 DolP-mannose mannosyltransferase TspO_MBR PF03073.15 OWF39583.1 - 1.9e-07 31.2 19.6 1.9e-07 31.2 19.6 3.2 2 2 0 2 2 2 1 TspO/MBR family TspO_MBR PF03073.15 OWF39584.1 - 1.9e-07 31.2 16.4 1.9e-07 31.2 16.4 3.4 2 1 0 2 2 2 1 TspO/MBR family TPR_12 PF13424.6 OWF39585.1 - 1.4e-14 54.2 15.0 3.4e-07 30.4 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF39585.1 - 5.7e-14 51.2 15.3 0.052 13.4 0.6 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OWF39585.1 - 1e-09 37.8 21.1 0.079 13.1 1.8 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF39585.1 - 7.9e-07 28.8 11.0 2.3 8.7 0.4 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF39585.1 - 0.0001 21.9 0.1 0.033 13.9 0.0 4.0 4 1 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 OWF39585.1 - 0.00047 20.6 5.9 2 9.0 0.4 4.5 2 2 1 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 OWF39585.1 - 0.00048 19.9 0.4 0.0014 18.3 0.2 1.8 1 1 1 2 2 2 1 26S proteasome subunit RPN7 ANAPC3 PF12895.7 OWF39585.1 - 0.0096 16.1 8.0 0.28 11.5 1.6 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 OWF39585.1 - 0.0097 15.3 1.4 0.37 10.1 1.5 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_9 PF13371.6 OWF39585.1 - 0.011 15.9 5.7 4 7.7 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF39585.1 - 0.013 15.5 11.4 0.15 12.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF39585.1 - 0.018 15.4 2.8 1.1 9.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF39585.1 - 0.044 14.4 7.4 9.8 7.1 0.4 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF39585.1 - 0.059 14.2 7.7 49 5.1 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF39585.1 - 0.14 12.8 9.3 6.6 7.5 0.4 4.2 3 1 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 OWF39585.1 - 0.16 11.7 2.5 4.7 6.9 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3856 PF12968.7 OWF39585.1 - 0.17 12.0 6.1 11 6.1 0.1 3.5 2 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 OWF39585.1 - 1.3 9.0 4.5 20 5.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Kelch_1 PF01344.25 OWF39586.1 - 3.4e-86 282.6 16.6 4.4e-18 64.6 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF39586.1 - 6.8e-42 140.4 8.5 3.2e-09 36.8 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 OWF39586.1 - 1.1e-38 129.8 8.0 1.9e-06 27.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 OWF39586.1 - 4.9e-31 107.2 0.4 1.1e-30 106.1 0.2 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF39586.1 - 1e-30 105.9 0.2 2e-30 104.9 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 OWF39586.1 - 2.1e-22 78.9 3.0 0.0016 18.4 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF39586.1 - 1e-16 60.7 3.8 0.014 15.7 0.0 5.6 6 0 0 6 6 6 5 Galactose oxidase, central domain DUF3342 PF11822.8 OWF39586.1 - 1.7e-07 31.3 0.2 1.3e-05 25.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 OWF39586.1 - 0.00016 21.6 17.8 2.5 8.2 0.1 5.8 6 0 0 6 6 6 4 Kelch motif HRG PF16954.5 OWF39587.1 - 2.6e-14 53.3 18.5 2e-11 44.1 7.0 3.0 3 0 0 3 3 3 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene Popeye PF04831.13 OWF39587.1 - 2.7 8.2 8.9 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Popeye protein conserved region HRG PF16954.5 OWF39588.1 - 1.3e-16 60.8 16.3 4.8e-14 52.5 4.1 3.0 3 0 0 3 3 3 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene HTH_AraC PF00165.23 OWF39588.1 - 0.15 12.2 0.5 0.3 11.2 0.5 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF1673 PF07895.11 OWF39588.1 - 0.2 11.4 2.4 0.14 11.8 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) TssO PF17561.2 OWF39588.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.5 2 1 1 3 3 3 0 Type VI secretion system, TssO DUF4199 PF13858.6 OWF39588.1 - 5.1 7.5 7.8 1.8 8.9 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) H_lectin PF09458.10 OWF39589.1 - 4.5e-07 30.0 0.2 4.5e-07 30.0 0.2 2.6 2 1 0 2 2 2 1 H-type lectin domain Spc7 PF08317.11 OWF39589.1 - 0.00029 19.8 14.7 0.025 13.5 11.0 2.9 2 1 1 3 3 3 2 Spc7 kinetochore protein Matrilin_ccoil PF10393.9 OWF39589.1 - 0.0016 18.2 1.6 0.63 9.9 0.7 4.1 3 0 0 3 3 3 1 Trimeric coiled-coil oligomerisation domain of matrilin TACC_C PF05010.14 OWF39589.1 - 0.0056 16.5 4.8 0.0056 16.5 4.8 1.7 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal V_ATPase_I PF01496.19 OWF39589.1 - 0.0058 14.6 9.7 0.077 10.9 9.1 2.0 1 1 1 2 2 2 1 V-type ATPase 116kDa subunit family ATG16 PF08614.11 OWF39589.1 - 0.02 15.1 16.6 0.039 14.2 12.6 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1834 PF08873.11 OWF39589.1 - 0.025 14.3 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) Filament PF00038.21 OWF39589.1 - 0.029 13.9 16.4 0.039 13.5 9.2 2.8 1 1 2 3 3 3 0 Intermediate filament protein IFT57 PF10498.9 OWF39589.1 - 0.057 12.4 12.8 0.016 14.2 8.8 2.1 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 sCache_like PF16736.5 OWF39589.1 - 0.064 13.4 7.8 0.12 12.5 6.5 2.1 1 1 1 2 2 2 0 Single Cache-like Slp PF03843.13 OWF39589.1 - 0.066 12.6 0.1 0.22 10.9 0.0 1.9 3 0 0 3 3 1 0 Outer membrane lipoprotein Slp family MAD PF05557.13 OWF39589.1 - 0.1 11.0 15.2 0.38 9.1 11.7 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF3552 PF12072.8 OWF39589.1 - 0.18 11.2 7.4 0.35 10.3 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HrpB7 PF09486.10 OWF39589.1 - 0.21 12.0 5.8 1.7 9.0 4.7 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 OWF39589.1 - 0.21 11.6 14.5 4.7 7.2 0.2 3.6 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1706 PF08020.11 OWF39589.1 - 0.24 11.3 4.4 0.4 10.6 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1706) APG6_N PF17675.1 OWF39589.1 - 0.25 11.9 7.1 1.7 9.2 6.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 OWF39589.1 - 0.28 11.2 15.8 0.1 12.7 11.4 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OWF39589.1 - 0.65 10.4 12.2 8.5 6.8 10.5 2.6 1 1 0 2 2 2 0 Fez1 Tup_N PF08581.10 OWF39589.1 - 0.7 10.2 10.2 8 6.9 0.5 3.7 2 1 1 3 3 3 0 Tup N-terminal BST2 PF16716.5 OWF39589.1 - 0.92 10.1 0.0 0.92 10.1 0.0 4.2 3 1 1 4 4 3 0 Bone marrow stromal antigen 2 Sipho_Gp157 PF05565.11 OWF39589.1 - 0.98 9.4 7.3 6.2 6.8 5.7 2.5 1 1 1 2 2 2 0 Siphovirus Gp157 M PF02370.16 OWF39589.1 - 1 10.1 11.3 0.88 10.3 1.1 4.0 3 0 0 3 3 3 0 M protein repeat ADIP PF11559.8 OWF39589.1 - 1.5 8.9 20.6 1.5 8.9 6.6 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 OWF39589.1 - 1.6 7.9 16.9 0.24 10.6 9.4 2.6 1 1 1 3 3 3 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 OWF39589.1 - 1.6 8.8 17.5 0.3 11.1 2.7 3.0 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 OWF39589.1 - 1.8 7.0 5.2 0.53 8.7 2.4 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF724 PF05266.14 OWF39589.1 - 2 8.2 8.6 49 3.7 5.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 OWF39589.1 - 2.2 8.6 18.1 2 8.7 4.5 3.6 3 1 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 OWF39589.1 - 2.3 8.4 26.8 0.3 11.3 11.7 3.9 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family CHDCT2 PF08074.11 OWF39589.1 - 3 8.0 11.4 0.63 10.2 5.5 2.6 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain Nup54 PF13874.6 OWF39589.1 - 3.3 7.8 14.1 0.34 11.0 2.9 3.5 2 2 0 3 3 3 0 Nucleoporin complex subunit 54 DUF1664 PF07889.12 OWF39589.1 - 3.6 7.6 17.9 2.2 8.4 8.5 4.0 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) PolyA_pol PF01743.20 OWF39589.1 - 4.6 7.7 5.6 28 5.2 0.0 2.6 2 1 0 2 2 2 0 Poly A polymerase head domain DUF3450 PF11932.8 OWF39589.1 - 4.6 6.5 21.4 1 8.6 14.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 OWF39589.1 - 4.8 7.2 16.2 27 4.9 1.4 4.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.13 OWF39589.1 - 5.7 7.1 11.7 8.9 6.5 2.0 4.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.9 OWF39589.1 - 6.3 7.5 6.1 20 5.9 1.3 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) CLZ PF16526.5 OWF39589.1 - 6.4 7.2 10.7 22 5.5 0.9 3.9 2 1 1 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 OWF39589.1 - 7.2 7.3 16.2 3 8.5 0.8 4.0 2 1 1 3 3 3 0 SlyX FAM76 PF16046.5 OWF39589.1 - 7.6 5.8 14.0 2 7.7 9.8 2.0 2 0 0 2 2 2 0 FAM76 protein BRE1 PF08647.11 OWF39589.1 - 9.3 6.4 23.2 2.5 8.2 3.2 3.4 3 1 1 4 4 3 0 BRE1 E3 ubiquitin ligase Ric8 PF10165.9 OWF39591.1 - 1.5e-121 406.6 0.8 1.5e-121 406.6 0.8 1.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Urb2 PF10441.9 OWF39591.1 - 0.02 14.8 0.1 0.093 12.7 0.1 2.1 2 0 0 2 2 2 0 Urb2/Npa2 family WW PF00397.26 OWF39592.1 - 9.4e-12 44.8 18.1 7.1e-07 29.2 5.1 2.7 2 0 0 2 2 2 2 WW domain Mucin-like PF16058.5 OWF39593.1 - 1.2e-13 50.9 11.9 3.1e-05 24.0 1.6 3.4 1 1 2 3 3 3 3 Mucin-like zf-ZPR1 PF03367.13 OWF39594.1 - 8.5e-109 360.5 0.9 9.1e-55 184.9 0.2 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain CpXC PF14353.6 OWF39594.1 - 0.023 14.7 0.5 7.6 6.6 0.3 2.7 2 0 0 2 2 2 0 CpXC protein Elf1 PF05129.13 OWF39594.1 - 1.7 8.7 5.1 8 6.6 1.0 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.12 OWF39594.1 - 2.7 8.1 6.8 1.1 9.3 1.3 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 OWF39594.1 - 6.8 6.3 14.1 21 4.7 2.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Ig_3 PF13927.6 OWF39595.1 - 7e-58 193.2 3.5 2.7e-16 59.9 0.2 5.4 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 OWF39595.1 - 1.4e-51 172.5 0.0 1.3e-16 60.5 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF39595.1 - 4e-35 120.0 3.8 1e-10 41.8 0.0 5.2 6 0 0 6 6 5 4 Immunoglobulin domain ig PF00047.25 OWF39595.1 - 4.3e-31 106.9 1.6 8.5e-09 35.5 0.1 5.1 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 OWF39595.1 - 9.6e-17 61.1 11.1 1.7e-09 37.9 2.1 3.6 3 0 0 3 3 3 2 Fibronectin type III domain V-set PF07686.17 OWF39595.1 - 4.8e-16 58.9 12.4 0.00055 20.1 0.0 8.2 5 3 3 8 8 8 5 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF39595.1 - 9.6e-08 31.5 0.0 0.25 10.9 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF39595.1 - 3.2e-06 27.1 0.0 0.22 11.6 0.0 4.3 4 0 0 4 4 4 2 C17orf99 Ig domain Tissue_fac PF01108.17 OWF39595.1 - 6e-06 26.1 3.7 0.0019 18.0 1.0 2.7 2 0 0 2 2 2 2 Tissue factor C2-set_2 PF08205.12 OWF39595.1 - 2.7e-05 24.1 2.0 0.28 11.3 0.1 4.0 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF39595.1 - 0.0088 16.1 0.0 31 4.7 0.0 4.3 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain V-set PF07686.17 OWF39596.1 - 1.1e-09 38.4 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 OWF39596.1 - 3.1e-07 30.9 0.0 4.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF39596.1 - 0.00095 19.2 0.0 0.0017 18.4 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF39596.1 - 0.0015 18.7 0.0 0.0062 16.7 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Imm27 PF15590.6 OWF39598.1 - 4.5e-12 45.6 72.2 6.2 6.7 0.4 15.7 1 1 28 29 29 29 28 Immunity protein 27 DUF4115 PF13464.6 OWF39598.1 - 1.1e-10 41.5 68.6 81 3.5 0.2 27.6 1 1 30 31 31 31 3 Domain of unknown function (DUF4115) DUF1344 PF07076.11 OWF39599.1 - 0.11 12.4 0.0 20 5.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1344) PGDYG PF14083.6 OWF39599.1 - 4.1 7.7 11.3 2.8 8.2 0.5 3.1 1 1 2 3 3 3 0 PGDYG protein MORN_2 PF07661.13 OWF39599.1 - 5.8 7.5 7.0 63 4.3 0.1 3.8 1 1 5 6 6 6 0 MORN repeat variant PAS PF00989.25 OWF39599.1 - 8.2 6.5 6.9 22 5.1 1.2 2.7 1 1 3 4 4 4 0 PAS fold EF-hand_1 PF00036.32 OWF39600.1 - 0.00051 19.4 0.7 0.72 9.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF39600.1 - 0.00065 20.1 0.1 0.001 19.5 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 OWF39600.1 - 0.026 14.5 0.3 1.5 8.8 0.2 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 OWF39600.1 - 0.061 13.3 0.2 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 OWF39600.1 - 0.12 12.6 0.1 0.79 10.0 0.1 2.0 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_6 PF13405.6 OWF39602.1 - 0.0075 16.1 0.6 0.059 13.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OWF39602.1 - 0.039 14.4 2.9 0.058 13.8 1.8 2.0 2 1 0 2 2 2 0 EF-hand domain pair UBX PF00789.20 OWF39602.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 UBX domain DUF3804 PF12707.7 OWF39602.1 - 0.13 12.0 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) PhyH PF05721.13 OWF39603.1 - 2.5e-28 99.8 1.0 3e-28 99.5 1.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1722 PF08349.11 OWF39603.1 - 0.15 12.3 0.1 4.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Strabismus PF06638.11 OWF39604.1 - 1.6e-222 739.7 0.0 1.9e-222 739.4 0.0 1.0 1 0 0 1 1 1 1 Strabismus protein DUF871 PF05913.11 OWF39604.1 - 0.0046 16.2 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF871) MtN3_slv PF03083.16 OWF39604.1 - 0.17 11.9 5.1 0.59 10.2 2.6 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4131 PF13567.6 OWF39604.1 - 0.92 9.1 4.3 0.7 9.5 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) 60KD_IMP PF02096.20 OWF39605.1 - 1.1e-14 54.7 0.0 2.7e-13 50.1 0.0 2.7 2 1 0 2 2 2 1 60Kd inner membrane protein DUF624 PF04854.14 OWF39605.1 - 2 8.6 5.1 1.7 8.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Lipase_GDSL_2 PF13472.6 OWF39606.1 - 4.1e-14 53.4 0.0 5.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF39606.1 - 1.6e-05 25.0 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 OWF39606.1 - 0.007 16.5 0.0 0.0088 16.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family IHHNV_capsid PF16530.5 OWF39606.1 - 0.084 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid IcmF_C PF06744.12 OWF39607.1 - 1.4e-09 37.9 6.2 0.46 10.1 0.1 5.6 2 2 4 6 6 6 6 Type VI secretion protein IcmF C-terminal Adap_comp_sub PF00928.21 OWF39608.1 - 2e-34 119.1 0.0 2.9e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OWF39608.1 - 1.8e-08 34.4 0.2 3e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RhoGAP PF00620.27 OWF39609.1 - 9e-44 149.0 0.0 2.7e-43 147.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain SH3_2 PF07653.17 OWF39609.1 - 1.4e-09 37.5 0.0 3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OWF39609.1 - 2e-09 37.2 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF39609.1 - 1.8e-07 30.7 0.0 3.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PX PF00787.24 OWF39609.1 - 5.6e-06 26.3 0.3 1.9e-05 24.6 0.3 1.9 1 0 0 1 1 1 1 PX domain Ctr PF04145.15 OWF39610.1 - 4.2e-25 89.1 11.6 1.9e-23 83.8 11.6 2.0 1 1 0 1 1 1 1 Ctr copper transporter family cNMP_binding PF00027.29 OWF39611.1 - 3.2e-22 78.4 0.1 3.2e-16 59.2 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain PRIMA1 PF16101.5 OWF39611.1 - 0.048 13.7 1.0 0.13 12.3 1.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 cNMP_binding PF00027.29 OWF39612.1 - 1.1e-06 28.6 0.1 0.0044 17.0 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain CBM_14 PF01607.24 OWF39613.1 - 1.7e-10 40.9 25.3 1.6e-07 31.3 3.1 3.4 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Laminin_G_3 PF13385.6 OWF39613.1 - 2.7e-08 34.1 0.1 1e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily ETF_QO PF05187.13 OWF39614.1 - 3.6e-49 165.2 0.3 5.8e-49 164.6 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 OWF39614.1 - 4.6e-08 33.2 0.1 3.6e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF39614.1 - 4.6e-08 32.6 0.4 1.4e-05 24.4 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OWF39614.1 - 1.8e-07 31.1 0.0 8.8e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF39614.1 - 4.6e-06 26.1 0.0 6.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF39614.1 - 4.6e-06 26.0 0.0 1.1e-05 24.8 0.1 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 OWF39614.1 - 5.1e-05 22.8 0.3 7.9e-05 22.2 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OWF39614.1 - 9.9e-05 21.7 0.1 0.00016 21.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OWF39614.1 - 0.00016 22.2 0.1 0.46 11.1 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF39614.1 - 0.00019 21.4 0.1 0.00048 20.1 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OWF39614.1 - 0.0002 20.6 0.3 0.00028 20.1 0.3 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 OWF39614.1 - 0.0007 18.6 1.2 0.007 15.3 0.1 2.5 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 OWF39614.1 - 0.0025 16.6 0.3 0.0043 15.8 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Fer4_7 PF12838.7 OWF39614.1 - 0.011 16.3 1.7 0.011 16.3 1.7 2.2 3 0 0 3 3 2 0 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 OWF39614.1 - 0.024 13.9 0.4 0.035 13.3 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 OWF39614.1 - 0.12 12.6 1.0 0.48 10.6 1.0 2.1 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 OWF39614.1 - 0.18 10.9 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 OWF39614.1 - 0.24 10.5 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Cyt-b5 PF00173.28 OWF39615.1 - 7.8e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.27 OWF39616.1 - 1.8e-48 164.6 0.0 3.4e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OWF39616.1 - 1.1e-15 58.1 32.0 4e-11 43.1 5.7 3.5 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 OWF39616.1 - 6.2e-10 38.9 3.6 0.1 12.0 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OWF39616.1 - 1.4e-06 28.4 0.2 0.035 14.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 OWF39616.1 - 3.2e-05 24.1 1.5 0.03 14.4 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 OWF39616.1 - 0.00022 21.3 0.8 0.065 13.3 0.1 2.8 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 OWF39616.1 - 0.00024 21.1 0.3 0.56 10.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 OWF39616.1 - 0.00032 21.3 0.1 0.6 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 OWF39616.1 - 0.00058 19.6 0.0 0.0081 15.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_21 PF13304.6 OWF39616.1 - 0.00084 19.2 0.9 0.98 9.2 0.1 4.1 3 2 1 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF39616.1 - 0.0026 18.3 0.2 0.17 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF39616.1 - 0.0057 16.9 3.1 2.9 8.2 0.2 3.1 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 OWF39616.1 - 0.013 14.9 0.1 0.4 10.0 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 OWF39616.1 - 0.014 15.1 1.0 3.4 7.5 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OWF39616.1 - 0.02 14.4 0.4 3.3 7.2 0.2 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 OWF39616.1 - 0.024 13.6 0.0 6.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 OWF39616.1 - 0.041 13.6 0.7 1.3 8.7 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OWF39616.1 - 0.045 14.1 0.0 4.3 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase OstA_2 PF13100.6 OWF39616.1 - 0.072 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 OstA-like protein AAA_16 PF13191.6 OWF39616.1 - 0.11 12.9 0.3 6.5 7.1 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 OWF39616.1 - 0.11 11.3 0.4 3.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 OWF39616.1 - 0.12 11.5 3.0 1.6 7.9 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 OWF39616.1 - 0.14 11.3 0.4 4.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OWF39616.1 - 0.15 11.7 1.5 0.54 10.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OWF39616.1 - 0.21 11.3 1.3 54 3.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain PRK PF00485.18 OWF39616.1 - 0.24 11.1 1.4 1.9 8.2 0.2 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DEAD PF00270.29 OWF39616.1 - 0.7 9.6 4.7 1.2 8.8 1.3 2.7 2 1 0 2 2 1 0 DEAD/DEAH box helicase DUF4014 PF13198.6 OWF39616.1 - 1.6 9.2 4.7 0.39 11.1 0.7 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF4014) GH3 PF03321.13 OWF39617.1 - 1.2e-155 519.4 0.0 1.4e-155 519.1 0.0 1.1 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Phage_holin_3_6 PF07332.11 OWF39617.1 - 0.12 12.4 0.5 0.19 11.8 0.5 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PP2C PF00481.21 OWF39618.1 - 9.2e-79 264.7 0.0 1.2e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OWF39618.1 - 2.4e-07 30.6 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C MFS_1 PF07690.16 OWF39619.1 - 5.8e-15 55.1 52.2 2e-12 46.7 43.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RYDR_ITPR PF01365.21 OWF39620.1 - 1.4e-27 96.5 20.1 9.7e-22 77.4 2.1 3.7 3 0 0 3 3 3 2 RIH domain RIH_assoc PF08454.11 OWF39620.1 - 2.7e-22 78.5 0.8 2.7e-22 78.5 0.8 7.3 8 0 0 8 8 8 3 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 OWF39620.1 - 1.4e-21 76.7 1.2 2.5e-20 72.6 0.9 2.6 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 OWF39620.1 - 1.4e-15 57.6 2.4 1.8e-11 44.3 0.1 3.7 2 1 0 2 2 2 2 MIR domain Ion_trans PF00520.31 OWF39620.1 - 5.5e-07 29.1 19.5 3.7e-06 26.4 18.3 2.8 2 1 0 2 2 2 1 Ion transport protein DUF3361 PF11841.8 OWF39620.1 - 1.1 9.2 5.4 1.9 8.4 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) TTL PF03133.15 OWF39621.1 - 5.3e-90 301.5 0.2 7.5e-90 301.0 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF39621.1 - 6.5e-08 32.1 0.1 0.0018 17.6 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF39621.1 - 3.5e-05 23.2 0.0 0.0094 15.2 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 OWF39621.1 - 0.092 12.3 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CD36 PF01130.21 OWF39622.1 - 1.9e-138 461.9 4.7 2.4e-138 461.6 4.7 1.0 1 0 0 1 1 1 1 CD36 family Ytca PF17090.5 OWF39622.1 - 0.037 14.6 0.2 0.091 13.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family FH2 PF02181.23 OWF39623.1 - 2.1e-85 287.1 1.9 2.1e-85 287.1 0.3 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Formin_GBD_N PF18382.1 OWF39623.1 - 7e-15 55.3 0.9 1.3e-14 54.4 0.1 1.8 2 0 0 2 2 2 1 Formin N-terminal GTPase-binding domain DUF3361 PF11841.8 OWF39623.1 - 0.13 12.2 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) A_deamin PF02137.18 OWF39624.1 - 6.2e-98 328.3 0.0 2.5e-97 326.3 0.0 1.9 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Atg8 PF02991.16 OWF39625.1 - 2e-48 162.9 0.1 2.3e-48 162.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OWF39625.1 - 1.9e-05 24.9 0.0 2.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.25 OWF39626.1 - 3.6e-47 160.9 0.3 8.2e-47 159.8 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF39626.1 - 7e-23 81.2 0.0 1.6e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OWF39626.1 - 0.0085 15.1 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 OWF39626.1 - 0.0088 16.0 0.1 0.031 14.2 0.1 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_8 PF13855.6 OWF39627.1 - 9.7e-80 262.3 83.2 7e-14 51.3 7.1 11.2 7 3 4 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 OWF39627.1 - 7.5e-36 121.6 92.4 7.4e-05 23.0 2.3 14.8 6 5 11 18 18 18 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF39627.1 - 8.2e-32 109.9 21.6 2.8e-07 30.6 0.5 6.3 3 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF39627.1 - 7.8e-21 74.3 39.2 7.6e-06 25.5 2.5 7.2 2 2 5 7 7 7 7 Leucine-rich repeat TIR PF01582.20 OWF39627.1 - 5.4e-09 36.1 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF39627.1 - 9.7e-07 28.5 65.2 11 7.1 0.3 19.9 24 1 0 24 24 22 2 Leucine Rich Repeat TIR_2 PF13676.6 OWF39627.1 - 3e-06 27.8 0.0 1.1e-05 26.0 0.0 2.0 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.18 OWF39627.1 - 0.0025 17.4 0.3 0.0025 17.4 0.3 3.4 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_2 PF07723.13 OWF39627.1 - 0.022 15.4 3.0 16 6.4 0.2 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Suppressor_P21 PF11479.8 OWF39627.1 - 0.023 14.9 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain TPKR_C2 PF16920.5 OWF39627.1 - 0.18 11.9 0.3 0.8 9.9 0.3 2.2 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_8 PF13855.6 OWF39628.1 - 5.8e-79 259.8 83.5 3.1e-13 49.3 7.8 10.1 6 3 4 10 10 10 10 Leucine rich repeat LRR_5 PF13306.6 OWF39628.1 - 2.7e-33 114.7 16.6 6.8e-08 32.5 0.4 6.1 4 2 1 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF39628.1 - 1.2e-32 111.4 89.9 0.0001 22.6 3.7 13.8 3 2 11 17 17 17 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF39628.1 - 2.2e-17 63.1 39.3 2.8e-05 23.7 1.5 7.0 2 2 5 7 7 7 6 Leucine-rich repeat TIR PF01582.20 OWF39628.1 - 3.3e-10 40.0 0.0 5.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF39628.1 - 8.1e-08 32.9 0.0 2.4e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF39628.1 - 0.0019 18.5 66.1 6.1 7.8 0.0 18.4 21 1 0 21 21 21 1 Leucine Rich Repeat LRRNT PF01462.18 OWF39628.1 - 0.02 14.5 0.4 0.02 14.5 0.4 3.4 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 OWF39628.1 - 0.16 12.2 0.3 0.76 10.0 0.3 2.3 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain DKNYY PF13644.6 OWF39628.1 - 0.19 12.5 0.2 1.1 10.1 0.2 2.3 1 1 0 1 1 1 0 DKNYY family LRR_8 PF13855.6 OWF39629.1 - 1.2e-79 261.9 81.1 1.6e-12 47.0 8.0 10.1 6 3 4 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 OWF39629.1 - 2.3e-35 120.0 89.8 6.2e-05 23.3 0.8 13.8 6 3 8 16 16 16 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF39629.1 - 2.9e-34 117.8 17.5 3.2e-08 33.6 0.4 6.2 3 2 0 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF39629.1 - 1.3e-19 70.4 37.3 4.5e-05 23.0 1.3 7.2 2 2 5 7 7 7 7 Leucine-rich repeat TIR PF01582.20 OWF39629.1 - 1.3e-09 38.1 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF39629.1 - 2.9e-06 27.9 0.0 1.1e-05 26.0 0.0 2.0 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF39629.1 - 0.00085 19.5 65.9 3.6 8.5 0.5 19.1 23 1 0 23 23 23 2 Leucine Rich Repeat LRRNT PF01462.18 OWF39629.1 - 0.02 14.5 0.4 0.02 14.5 0.4 3.4 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 OWF39629.1 - 0.17 12.0 0.3 0.76 10.0 0.3 2.2 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain FNIP PF05725.12 OWF39629.1 - 0.42 10.8 13.1 1.2 9.3 0.1 5.8 6 0 0 6 6 6 0 FNIP Repeat FAM217 PF15344.6 OWF39630.1 - 1.3e-09 38.3 1.3 1.3e-09 38.3 1.3 3.0 2 2 1 3 3 3 1 FAM217 family DUF3685 PF12452.8 OWF39630.1 - 0.014 15.2 2.0 0.027 14.2 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF2553 PF10830.8 OWF39630.1 - 0.071 13.9 1.0 0.16 12.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2553) Ribosomal_L36 PF00444.18 OWF39631.1 - 9.8e-12 44.9 4.9 2.4e-11 43.7 4.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L36 PhoLip_ATPase_C PF16212.5 OWF39633.1 - 1e-49 169.6 23.7 1e-49 169.6 23.7 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OWF39633.1 - 2.2e-20 72.1 2.9 8e-20 70.3 2.9 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OWF39633.1 - 2.7e-14 54.0 0.6 1.2e-10 42.0 0.6 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OWF39633.1 - 7.4e-14 51.7 0.0 7.4e-14 51.7 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OWF39633.1 - 6e-11 42.3 0.0 1.6e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OWF39633.1 - 0.0025 17.6 0.0 0.0093 15.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CAP_GLY PF01302.25 OWF39634.1 - 5.3e-16 58.4 0.7 8.2e-16 57.8 0.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain CK2S PF15011.6 OWF39635.1 - 6.4e-29 100.9 5.8 8.7e-29 100.5 5.8 1.1 1 0 0 1 1 1 1 Casein Kinase 2 substrate Borealin PF10512.9 OWF39636.1 - 1.8e-12 47.3 0.3 1.8e-12 47.3 0.3 2.3 3 0 0 3 3 3 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.9 OWF39636.1 - 6.9e-10 38.4 0.9 1.5e-09 37.4 0.9 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF5409 PF17421.2 OWF39637.1 - 3.5e-08 34.0 39.9 0.6 10.9 0.8 8.1 1 1 7 9 9 9 9 Family of unknown function (DUF5409) tRNA-synt_1d PF00750.19 OWF39639.1 - 5.7e-72 242.6 1.3 1e-71 241.8 1.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OWF39639.1 - 8.2e-21 74.4 0.1 2.7e-20 72.7 0.1 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain Clathrin PF00637.20 OWF39639.1 - 0.013 15.4 1.7 1 9.2 0.2 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS zf-RNPHF PF08080.12 OWF39640.1 - 0.042 13.8 4.0 0.36 10.8 0.2 2.6 2 0 0 2 2 2 0 RNPHF zinc finger LPP20 PF02169.16 OWF39640.1 - 3.2 8.2 6.6 0.52 10.7 1.2 2.4 2 0 0 2 2 2 0 LPP20 lipoprotein RIH_assoc PF08454.11 OWF39640.1 - 9.9 6.1 10.4 0.32 10.9 1.2 2.8 2 1 0 2 2 2 0 RyR and IP3R Homology associated Tmemb_55A PF09788.9 OWF39641.1 - 3.7e-57 193.2 11.9 4.6e-57 192.9 11.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A IBR PF01485.21 OWF39641.1 - 0.013 15.7 1.7 0.013 15.7 1.7 3.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 OWF39641.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.3 4 0 0 4 4 4 0 zinc-ribbon domain DUF4674 PF15719.5 OWF39641.1 - 0.47 10.5 3.7 24 4.9 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) zinc_ribbon_12 PF11331.8 OWF39641.1 - 1.8 8.4 15.3 0.2 11.5 1.6 3.4 2 2 1 3 3 3 0 Probable zinc-ribbon domain TPR_1 PF00515.28 OWF39642.1 - 1.1e-06 28.2 20.2 0.13 12.2 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OWF39642.1 - 1.2e-06 28.5 0.7 0.036 14.1 0.1 3.4 3 0 0 3 3 3 2 Putative TPR-like repeat TPR_2 PF07719.17 OWF39642.1 - 8.9e-06 25.4 24.1 0.51 10.6 0.2 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF39642.1 - 7.9e-05 23.1 10.6 0.73 10.4 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF39642.1 - 0.00017 21.4 3.8 2.5 8.1 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF39642.1 - 0.00038 20.7 12.8 0.19 12.1 0.1 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF39642.1 - 0.00073 20.2 12.2 0.43 11.5 0.0 6.5 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF39642.1 - 0.0014 18.7 6.0 2.9 8.3 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF39642.1 - 0.01 16.1 4.5 17 6.0 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MKT1_N PF12247.8 OWF39642.1 - 0.07 13.5 0.2 21 5.5 0.0 2.7 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DUF2122 PF09895.9 OWF39642.1 - 0.14 12.5 0.0 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) ANAPC3 PF12895.7 OWF39642.1 - 0.43 10.8 20.8 0.92 9.8 0.6 6.4 5 2 3 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OWF39642.1 - 0.5 10.5 6.7 12 6.0 0.2 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 OWF39642.1 - 0.54 9.6 3.4 1.6 8.1 0.1 2.9 3 0 0 3 3 3 0 MalT-like TPR region TPR_16 PF13432.6 OWF39642.1 - 1.9 9.2 5.1 50 4.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF-1a PF01176.19 OWF39643.1 - 4.5e-09 36.0 3.2 0.46 10.3 0.1 6.0 1 1 2 5 5 5 3 Translation initiation factor 1A / IF-1 CfAFP PF05264.11 OWF39643.1 - 0.0019 18.2 7.8 1.7 8.7 0.3 4.0 1 1 3 4 4 4 2 Choristoneura fumiferana antifreeze protein (CfAFP) PH_15 PF17339.2 OWF39643.1 - 0.017 15.0 20.1 10 6.0 0.4 5.6 1 1 3 5 5 5 0 PH domain TMEM131_like PF12371.8 OWF39643.1 - 0.24 11.7 35.8 5 7.5 1.3 6.2 1 1 6 7 7 7 0 Transmembrane protein 131-like VWD PF00094.25 OWF39643.1 - 0.8 10.0 35.1 2 8.7 4.6 4.6 1 1 3 4 4 4 0 von Willebrand factor type D domain fn3_6 PF17766.1 OWF39643.1 - 0.89 9.8 30.6 0.56 10.4 0.7 6.0 1 1 3 4 4 4 0 Fibronectin type-III domain DUF1236 PF06823.12 OWF39643.1 - 1.8 8.5 33.4 9 6.3 0.0 10.1 7 4 1 9 9 9 0 Protein of unknown function (DUF1236) DUF4493 PF14900.6 OWF39643.1 - 5 6.9 28.4 7.1 6.4 2.2 5.5 1 1 1 2 2 1 0 Domain of unknown function (DUF4493) CTP-dep_RFKase PF01982.16 OWF39643.1 - 5.7 7.1 27.8 4.4 7.4 2.6 5.0 1 1 5 6 6 6 0 Domain of unknown function DUF120 PTH2 PF01981.16 OWF39643.1 - 8.4 6.7 31.9 62 3.9 1.6 8.7 1 1 6 7 7 7 0 Peptidyl-tRNA hydrolase PTH2 DUF4988 PF16378.5 OWF39643.1 - 8.9 5.9 15.5 14 5.3 0.3 4.8 1 1 5 6 6 6 0 Domain of unknown function Ntox33 PF15533.6 OWF39644.1 - 3.9 8.0 6.4 7.3 7.1 0.2 3.7 5 0 0 5 5 5 0 Bacterial toxin 33 NHL PF01436.21 OWF39646.1 - 2.1e-56 185.2 24.5 3.3e-10 39.5 0.2 6.6 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.19 OWF39646.1 - 4.2e-21 75.7 0.0 1.2e-20 74.2 0.0 1.9 1 0 0 1 1 1 1 Filamin/ABP280 repeat SGL PF08450.12 OWF39646.1 - 2.4e-16 60.1 0.7 6e-05 22.7 0.0 5.1 1 1 3 5 5 5 4 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 OWF39646.1 - 3.8e-12 46.0 3.3 0.00045 19.5 0.0 3.8 1 1 1 3 3 3 3 6-bladed beta-propeller zf-B_box PF00643.24 OWF39646.1 - 5.2e-08 32.9 24.4 1.3e-06 28.4 8.2 3.8 5 0 0 5 5 3 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF39646.1 - 7.1e-07 29.0 5.8 7.1e-07 29.0 5.8 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF39646.1 - 1.5e-06 27.9 2.2 1.5e-06 27.9 2.2 4.1 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF39646.1 - 1.8e-06 27.9 9.5 1.8e-06 27.9 9.5 2.5 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF39646.1 - 6.5e-06 26.0 6.1 6.5e-06 26.0 6.1 3.8 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF39646.1 - 5.2e-05 23.0 5.5 5.2e-05 23.0 5.5 4.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF39646.1 - 8.2e-05 22.7 5.2 8.2e-05 22.7 5.2 3.4 3 1 0 3 3 1 1 zinc finger of C3HC4-type, RING Phytase-like PF13449.6 OWF39646.1 - 0.00046 20.2 0.0 1.4 8.8 0.0 3.5 2 1 0 3 3 3 1 Esterase-like activity of phytase zf-RING_2 PF13639.6 OWF39646.1 - 0.00052 20.3 7.4 0.00052 20.3 7.4 3.6 3 0 0 3 3 3 1 Ring finger domain Invasin_D3 PF09134.10 OWF39646.1 - 0.0086 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Invasin, domain 3 Agenet PF05641.12 OWF39646.1 - 0.037 14.5 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 1 0 Agenet domain Lactonase PF10282.9 OWF39646.1 - 0.082 12.2 0.5 0.4 9.9 0.3 2.1 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Med3 PF11593.8 OWF39646.1 - 0.27 10.4 7.7 0.016 14.4 2.2 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Siva PF05458.12 OWF39646.1 - 0.36 10.5 17.2 1.4 8.6 6.9 2.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) ARA70 PF12489.8 OWF39646.1 - 0.56 10.4 4.3 0.33 11.2 0.6 2.1 2 0 0 2 2 2 0 Nuclear coactivator GFO_IDH_MocA PF01408.22 OWF39647.1 - 7.8e-11 42.9 0.0 2.7e-10 41.1 0.0 1.9 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 OWF39647.1 - 0.02 15.4 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.17 OWF39647.1 - 0.078 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PMSR PF01625.21 OWF39648.1 - 2.9e-09 37.3 0.5 4.2e-09 36.7 0.2 1.4 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase Sde2_N_Ubi PF13019.6 OWF39648.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Sulfatase_C PF14707.6 OWF39649.1 - 2.3e-17 63.9 0.1 2.9e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Sulfatase PF00884.23 OWF39649.1 - 1.6e-09 37.6 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Sulfatase PF00884.23 OWF39650.1 - 2e-39 135.8 0.0 2.6e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF39650.1 - 0.00022 20.9 0.0 0.00026 20.7 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase zf-C2H2 PF00096.26 OWF39651.1 - 4.7e-36 121.2 113.0 8.2e-05 22.9 0.9 14.0 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF39651.1 - 1.7e-32 109.2 110.1 0.00024 21.7 0.5 14.0 14 0 0 14 14 14 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF39651.1 - 1.2e-29 101.3 98.7 5.1e-07 29.8 0.0 14.2 14 0 0 14 14 14 8 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF39651.1 - 1.7e-09 37.7 76.0 0.058 13.7 0.7 13.4 13 0 0 13 13 12 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 OWF39651.1 - 2e-07 31.2 2.7 0.022 15.0 0.0 4.2 2 1 1 3 3 3 2 BolA-like protein zf-met PF12874.7 OWF39651.1 - 1.8e-05 25.0 75.0 0.02 15.3 0.4 12.3 13 0 0 13 13 12 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF39651.1 - 4.6e-05 23.3 93.7 0.00064 19.7 2.0 12.6 12 0 0 12 12 12 6 C2H2-type zinc finger zf-C2HE PF16278.5 OWF39651.1 - 0.023 15.2 1.3 0.023 15.2 1.3 11.1 7 3 4 11 11 11 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 OWF39651.1 - 0.054 13.3 5.4 16 5.4 0.8 3.9 3 1 0 3 3 3 0 GAGA factor POTRA_2 PF08479.11 OWF39651.1 - 0.06 13.2 0.2 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 POTRA domain, ShlB-type zf-C2H2_11 PF16622.5 OWF39651.1 - 0.062 13.1 55.8 0.39 10.5 0.1 10.0 10 1 1 11 11 11 0 zinc-finger C2H2-type PyrI_C PF02748.15 OWF39651.1 - 0.064 13.2 0.2 0.064 13.2 0.2 8.1 10 1 0 10 10 10 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 OWF39651.1 - 0.82 10.0 68.9 0.34 11.3 0.5 10.4 3 2 7 10 10 10 0 C2H2 type zinc-finger (2 copies) DSPc PF00782.20 OWF39652.1 - 1.3e-32 112.4 0.0 1.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF39652.1 - 0.00045 19.9 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase IRF PF00605.17 OWF39653.1 - 4.4e-39 133.0 0.3 7.5e-39 132.3 0.3 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 OWF39653.1 - 9.2e-36 123.3 0.0 1.3e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 MH2 PF03166.14 OWF39653.1 - 8.3e-07 29.4 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 MH2 domain MMR_HSR1_Xtn PF16897.5 OWF39654.1 - 0.0075 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Ras PF00071.22 OWF39654.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Ras family UreF PF01730.16 OWF39655.1 - 8.7e-05 23.1 2.0 1.5 9.4 0.3 3.4 1 1 2 3 3 3 2 UreF DUF1018 PF06252.12 OWF39655.1 - 0.0021 19.1 0.1 1 10.4 0.1 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1018) Topo_C_assoc PF14370.6 OWF39655.1 - 0.0042 17.0 4.8 39 4.3 0.0 6.8 2 2 6 8 8 8 0 C-terminal topoisomerase domain DUF3475 PF11961.8 OWF39655.1 - 0.32 11.1 5.4 16 5.6 0.1 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF3475) Tn7_TnsC_Int PF11426.8 OWF39655.1 - 1.8 8.8 8.6 31 4.9 0.1 5.3 7 1 1 8 8 8 0 Tn7 transposition regulator TnsC GTP1_OBG PF01018.22 OWF39656.1 - 2e-44 150.9 8.1 2.5e-44 150.6 8.1 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 OWF39656.1 - 5.3e-10 39.4 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OWF39656.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Dynamin family FeoB_N PF02421.18 OWF39656.1 - 0.081 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 OWF39656.1 - 0.092 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TMEM189_B_dmain PF10520.9 OWF39657.1 - 1.7e-75 252.9 3.5 1.7e-75 252.9 3.5 1.4 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain VPS13_mid_rpt PF16910.5 OWF39658.1 - 1.8e-82 276.3 21.0 3.6e-71 239.3 0.5 7.0 6 1 0 6 6 6 4 Repeating coiled region of VPS13 VPS13_C PF16909.5 OWF39658.1 - 1.7e-63 213.6 3.4 1.8e-60 203.8 0.1 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 OWF39658.1 - 6.6e-60 202.8 16.2 5.9e-55 186.6 8.4 5.5 4 1 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OWF39658.1 - 3.5e-40 136.7 0.4 3.5e-40 136.7 0.4 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 OWF39658.1 - 1.8e-30 106.3 1.3 2.1e-18 66.7 0.0 4.6 3 1 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 OWF39658.1 - 1.9e-10 41.0 0.0 8.3e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain WWE PF02825.20 OWF39658.1 - 0.023 15.3 0.0 0.11 13.1 0.0 2.2 1 0 0 1 1 1 0 WWE domain Rapsyn_N PF10579.9 OWF39658.1 - 0.1 12.7 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Adaptin_N PF01602.20 OWF39659.1 - 7.5e-73 245.9 15.9 1.4e-72 245.0 15.9 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OWF39659.1 - 9.2e-09 35.5 5.3 3.3e-08 33.7 0.5 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OWF39659.1 - 2.1e-05 24.8 0.1 1.7 9.1 0.0 3.9 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 OWF39659.1 - 0.0042 17.2 0.3 0.19 12.1 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat MA3 PF02847.17 OWF39659.1 - 0.063 13.3 3.2 1.1 9.3 0.1 3.5 4 0 0 4 4 4 0 MA3 domain HEAT_EZ PF13513.6 OWF39659.1 - 0.22 12.1 0.2 5 7.7 0.1 2.8 2 0 0 2 2 2 0 HEAT-like repeat BTB PF00651.31 OWF39660.1 - 4.4e-21 75.2 0.1 3.5e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF39660.1 - 2.3e-12 46.9 0.6 4.9e-10 39.4 0.1 2.8 1 1 1 2 2 2 2 BTB And C-terminal Kelch Frag1 PF10277.9 OWF39661.1 - 2.3e-42 145.0 17.8 2.6e-42 144.8 17.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EVC2_like PF12297.8 OWF39661.1 - 0.0014 17.4 1.4 0.0019 17.0 1.4 1.2 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein ASC PF00858.24 OWF39662.1 - 1.3e-32 113.4 0.0 1.8e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TIP49_C PF17856.1 OWF39662.1 - 0.075 13.2 0.2 0.56 10.4 0.0 2.4 2 1 1 3 3 3 0 TIP49 AAA-lid domain LYRIC PF15686.5 OWF39662.1 - 0.19 11.2 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family ASC PF00858.24 OWF39663.1 - 0.023 13.7 0.2 0.043 12.8 0.2 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel VWD PF00094.25 OWF39664.1 - 1e-08 35.6 2.9 1.4e-07 31.9 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type D domain EGF_2 PF07974.13 OWF39664.1 - 0.0027 18.0 14.8 0.0027 18.0 14.8 3.1 4 0 0 4 4 4 1 EGF-like domain Toxin_2 PF00451.19 OWF39664.1 - 1.5 9.2 8.2 7.2 7.0 8.2 2.3 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 EGF_2 PF07974.13 OWF39666.1 - 0.00021 21.6 15.3 0.0013 19.0 15.3 2.5 1 0 0 1 1 1 1 EGF-like domain VWD PF00094.25 OWF39666.1 - 0.00055 20.2 1.0 0.00055 20.2 1.0 2.8 2 0 0 2 2 2 1 von Willebrand factor type D domain TMEM154 PF15102.6 OWF39666.1 - 0.011 15.7 0.2 0.037 13.9 0.2 1.9 1 0 0 1 1 1 0 TMEM154 protein family EGF_Tenascin PF18720.1 OWF39666.1 - 3 8.0 23.0 0.024 14.7 12.0 3.1 3 0 0 3 3 3 0 Tenascin EGF domain RIFIN PF02009.16 OWF39667.1 - 0.00038 20.4 4.2 0.0005 20.1 4.2 1.3 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 OWF39667.1 - 0.00078 19.4 11.3 0.0019 18.1 11.3 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF2207 PF09972.9 OWF39667.1 - 0.023 13.5 0.1 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.18 OWF39667.1 - 0.12 12.6 7.3 0.25 11.6 7.3 1.5 1 0 0 1 1 1 0 Glycophorin A FSA_C PF10479.9 OWF39667.1 - 0.14 10.2 17.9 0.18 9.9 17.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1180 PF06679.12 OWF39667.1 - 0.27 11.6 5.8 0.53 10.7 5.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF5383 PF17355.2 OWF39667.1 - 0.38 11.1 1.6 0.8 10.1 1.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF5305 PF17231.2 OWF39667.1 - 1.2 8.5 15.2 1.9 7.9 15.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) AJAP1_PANP_C PF15298.6 OWF39667.1 - 9.6 6.4 34.7 1.1 9.4 29.8 1.8 1 1 1 2 2 2 0 AJAP1/PANP C-terminus Pex14_N PF04695.13 OWF39669.1 - 0.11 13.2 12.8 0.14 12.9 3.6 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Epiglycanin_C PF14654.6 OWF39669.1 - 0.27 11.3 4.3 2.4 8.3 0.2 3.1 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region PROL5-SMR PF15621.6 OWF39669.1 - 2.7 8.5 6.6 6.8 7.3 0.9 2.6 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Mucin PF01456.17 OWF39669.1 - 4.3 7.3 45.5 0.34 10.9 12.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein VWD PF00094.25 OWF39670.1 - 1.7e-09 38.2 1.5 1.7e-09 38.2 1.5 2.0 2 0 0 2 2 2 1 von Willebrand factor type D domain SKG6 PF08693.10 OWF39670.1 - 0.00013 21.3 5.4 0.00026 20.3 5.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EGF_2 PF07974.13 OWF39670.1 - 0.0017 18.6 17.6 0.0017 18.6 17.6 3.1 3 0 0 3 3 3 1 EGF-like domain Mid2 PF04478.12 OWF39670.1 - 0.011 15.6 0.7 0.025 14.4 0.7 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EGF_Tenascin PF18720.1 OWF39670.1 - 0.076 13.1 17.8 0.017 15.2 13.0 2.6 2 0 0 2 2 2 0 Tenascin EGF domain EGF PF00008.27 OWF39670.1 - 4.6 7.6 23.7 0.27 11.6 11.9 3.5 3 0 0 3 3 3 0 EGF-like domain EamA PF00892.20 OWF39671.1 - 0.035 14.3 0.1 0.045 13.9 0.1 1.1 1 0 0 1 1 1 0 EamA-like transporter family Yip1 PF04893.17 OWF39671.1 - 0.049 13.4 1.1 0.058 13.1 1.1 1.1 1 0 0 1 1 1 0 Yip1 domain Phage_HK97_TLTM PF06120.11 OWF39671.1 - 0.16 11.2 0.3 0.18 10.9 0.3 1.1 1 0 0 1 1 1 0 Tail length tape measure protein CCDC158 PF15921.5 OWF39672.1 - 3.2e-79 267.1 131.5 8.2e-74 249.2 111.9 2.7 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 158 Laminin_II PF06009.12 OWF39672.1 - 0.0034 17.4 2.6 0.0034 17.4 2.6 12.3 4 2 8 14 14 14 4 Laminin Domain II DNA_RNApol_7kD PF03604.13 OWF39673.1 - 1.8e-05 24.3 2.3 0.44 10.3 0.0 3.9 3 0 0 3 3 3 2 DNA directed RNA polymerase, 7 kDa subunit Inhibitor_I48 PF10467.9 OWF39673.1 - 0.00025 20.9 3.2 2.5 8.0 0.1 4.0 1 1 4 5 5 5 3 Peptidase inhibitor clitocypin Peptidase_C41 PF05417.11 OWF39673.1 - 0.0013 18.6 0.7 37 4.1 0.0 4.1 1 1 2 4 4 4 0 Hepatitis E cysteine protease B12D PF06522.11 OWF39673.1 - 0.011 15.5 7.8 25 4.7 0.0 6.1 1 1 7 8 8 8 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-C2H2_7 PF15269.6 OWF39673.1 - 0.019 15.0 7.2 21 5.3 0.1 5.2 3 3 2 5 5 5 0 Zinc-finger DUF4535 PF15054.6 OWF39673.1 - 0.28 11.0 21.1 5.6 6.8 0.8 5.8 5 1 1 6 6 6 0 Domain of unknown function (DUF4535) Glyco_hydro_43 PF04616.14 OWF39673.1 - 0.51 9.6 8.0 3.9 6.7 0.6 2.6 2 1 0 2 2 2 0 Glycosyl hydrolases family 43 Gag_p30 PF02093.16 OWF39673.1 - 2 7.9 7.9 19 4.7 0.5 3.3 1 1 3 4 4 4 0 Gag P30 core shell protein Uma2 PF05685.12 OWF39673.1 - 2.6 7.6 9.7 21 4.6 0.1 4.3 1 1 4 5 5 5 0 Putative restriction endonuclease Glyco_hydro_35 PF01301.19 OWF39674.1 - 8.7e-43 147.1 0.0 1.2e-42 146.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Spin-Ssty PF02513.17 OWF39676.1 - 0.06 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Spin/Ssty Family adh_short PF00106.25 OWF39678.1 - 8.9e-22 77.5 0.2 4.8e-21 75.1 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39678.1 - 1.9e-10 40.7 0.1 4.9e-10 39.4 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF39678.1 - 0.0045 16.9 0.1 0.024 14.5 0.1 2.0 1 1 0 1 1 1 1 KR domain DUF4479 PF14794.6 OWF39678.1 - 0.028 14.3 0.1 0.21 11.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) ETC_C1_NDUFA5 PF04716.14 OWF39679.1 - 1.6 8.6 5.9 48 3.9 0.0 4.1 5 0 0 5 5 5 0 ETC complex I subunit conserved region adh_short PF00106.25 OWF39680.1 - 1.4e-22 80.1 0.1 2e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39680.1 - 1.3e-10 41.2 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF39680.1 - 0.0044 16.9 0.1 0.0073 16.2 0.1 1.3 1 1 0 1 1 1 1 KR domain FIST_C PF10442.9 OWF39680.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 FIST C domain adh_short PF00106.25 OWF39681.1 - 3.1e-23 82.2 0.0 5.6e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39681.1 - 6.3e-11 42.3 0.0 1.1e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF39682.1 - 1.3e-23 83.5 0.0 2.3e-23 82.7 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39682.1 - 9.1e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF39683.1 - 1.2e-23 83.6 0.0 2.5e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39683.1 - 4.3e-10 39.6 0.0 6.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF39684.1 - 8.2e-21 74.3 0.0 4.4e-20 72.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39684.1 - 9.9e-12 44.9 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF39685.1 - 1e-19 70.8 0.0 6.1e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39685.1 - 1.1e-10 41.5 0.0 2.3e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF39686.1 - 1.5e-21 76.8 0.0 3.1e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39686.1 - 7.5e-11 42.0 0.2 2.4e-10 40.4 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF4479 PF14794.6 OWF39686.1 - 0.007 16.2 0.1 0.042 13.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4479) adh_short PF00106.25 OWF39687.1 - 7.9e-22 77.7 0.0 2.3e-21 76.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39687.1 - 3e-09 36.8 0.0 8e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF39688.1 - 2.8e-19 69.3 0.0 1.9e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39688.1 - 6.6e-09 35.7 0.1 1.4e-08 34.6 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4479 PF14794.6 OWF39688.1 - 0.012 15.5 0.0 0.075 12.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) adh_short PF00106.25 OWF39689.1 - 4.1e-21 75.3 0.2 1.2e-20 73.8 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF39689.1 - 1.2e-11 44.6 0.4 3.5e-11 43.1 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF39689.1 - 0.091 12.7 0.2 0.24 11.3 0.2 1.7 1 1 0 1 1 1 0 KR domain HECT PF00632.25 OWF39690.1 - 1.2e-11 44.7 0.0 2.2e-10 40.5 0.0 2.2 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Frizzled PF01534.17 OWF39693.1 - 7.9e-136 452.4 18.7 1.1e-135 451.9 18.7 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 OWF39693.1 - 8.6e-30 103.6 3.1 8.6e-30 103.6 3.1 2.3 2 1 0 2 2 2 1 Fz domain Dicty_CAR PF05462.11 OWF39693.1 - 0.00015 21.0 5.2 0.00015 21.0 5.2 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Hormone_5 PF00184.17 OWF39694.1 - 0.066 14.0 55.1 37 5.2 2.5 9.7 1 1 4 5 5 5 0 Neurohypophysial hormones, C-terminal Domain Retinin_C PF04527.12 OWF39694.1 - 7.3 6.9 13.7 14 6.0 0.1 6.0 5 3 1 6 6 6 0 Drosophila Retinin like protein Cnd1 PF12717.7 OWF39696.1 - 5.1e-08 33.1 11.7 1.6 8.8 0.5 5.9 3 3 3 6 6 6 5 non-SMC mitotic condensation complex subunit 1 Tox-MPTase5 PF15641.6 OWF39696.1 - 7.2e-06 26.0 0.2 40 4.3 0.0 6.2 1 1 8 9 9 9 0 Metallopeptidase toxin 5 Ligase_CoA PF00549.19 OWF39696.1 - 2.8e-05 24.0 19.1 1 9.2 0.4 5.9 1 1 4 5 5 5 4 CoA-ligase ADK PF00406.22 OWF39696.1 - 0.00011 22.3 1.0 46 4.1 0.1 6.4 1 1 6 7 7 7 0 Adenylate kinase DUF4224 PF13986.6 OWF39696.1 - 0.00017 21.4 12.4 17 5.4 0.0 9.3 8 5 2 11 11 11 3 Domain of unknown function (DUF4224) Med17 PF10156.9 OWF39696.1 - 0.02 13.6 0.3 62 2.1 0.0 4.9 1 1 3 6 6 6 0 Subunit 17 of Mediator complex Baculo_PEP_C PF04513.12 OWF39697.1 - 2.9e-12 46.8 0.3 0.043 13.8 0.0 7.2 1 1 2 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus Tnp_22_dsRBD PF17490.2 OWF39698.1 - 0.0096 15.9 1.8 26 4.9 0.1 4.3 1 1 3 4 4 4 1 L1 transposable element dsRBD-like domain NdhS PF11623.8 OWF39698.1 - 8.6 6.1 17.0 24 4.7 0.5 4.1 1 1 4 5 5 5 0 NAD(P)H dehydrogenase subunit S Ank_2 PF12796.7 OWF39699.1 - 7.7e-40 135.4 4.1 4.2e-16 59.3 1.3 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF39699.1 - 5.2e-32 109.5 6.8 1.6e-07 31.5 0.6 6.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF39699.1 - 1e-28 99.3 6.1 5e-10 39.7 0.1 5.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF39699.1 - 3.3e-28 96.9 14.6 0.00066 20.0 0.2 7.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 OWF39699.1 - 2.5e-25 85.7 5.4 0.00057 20.1 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat AbfS_sensor PF18225.1 OWF39699.1 - 0.015 15.2 0.3 0.036 14.0 0.3 1.6 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain Macro PF01661.21 OWF39700.1 - 2.9e-09 37.0 0.0 1.1e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 Macro domain Macro_2 PF14519.6 OWF39700.1 - 6.8e-07 28.9 0.0 8.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Macro-like domain Med8 PF10232.9 OWF39700.1 - 0.51 9.9 2.2 0.82 9.2 2.2 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 WD40 PF00400.32 OWF39701.1 - 3.7e-28 97.2 14.2 2.2e-07 31.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 OWF39701.1 - 4.3e-28 97.4 1.5 3.9e-27 94.3 0.3 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 OWF39701.1 - 3e-05 24.2 2.0 0.017 15.4 0.0 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF39701.1 - 0.00016 21.6 0.5 0.034 14.0 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A EF-hand_4 PF12763.7 OWF39702.1 - 0.00025 20.9 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 OWF39702.1 - 0.046 13.7 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 OWF39702.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 EF hand Glycos_transf_2 PF00535.26 OWF39703.1 - 1.4e-30 106.3 0.0 2.7e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF39703.1 - 1.6e-27 96.3 2.0 3e-27 95.4 2.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 OWF39703.1 - 3.8e-06 26.5 1.0 2e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 OWF39703.1 - 0.0056 17.4 0.1 0.077 13.7 0.2 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like GerE PF00196.19 OWF39704.1 - 0.0047 16.4 0.0 1.7 8.2 0.0 4.1 2 2 3 5 5 5 1 Bacterial regulatory proteins, luxR family m_DGTX_Dc1a_b_c PF17491.2 OWF39704.1 - 2.4 8.9 16.6 24 5.6 2.3 4.4 1 1 3 4 4 4 0 Spider Toxins mu-diguetoxin-1 a, b and c NHL PF01436.21 OWF39705.1 - 2.8e-05 23.9 6.9 0.45 10.6 0.4 4.5 5 0 0 5 5 5 2 NHL repeat Reg_prop PF07494.11 OWF39705.1 - 0.0014 18.6 0.1 16 6.1 0.0 5.0 5 0 0 5 5 5 1 Two component regulator propeller SGL PF08450.12 OWF39705.1 - 0.034 13.7 0.3 6.3 6.3 0.0 3.3 1 1 3 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OWF39705.1 - 0.038 14.0 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Beta-propeller repeat ABC_tran PF00005.27 OWF39706.1 - 8.7e-46 155.8 0.0 1.3e-26 93.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OWF39706.1 - 7.6e-30 104.5 39.3 5.7e-23 81.9 7.2 3.4 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 OWF39706.1 - 3e-10 39.9 1.5 0.019 14.4 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OWF39706.1 - 2.3e-06 27.6 0.7 0.028 14.5 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 OWF39706.1 - 2.4e-06 27.6 2.2 0.6 9.9 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OWF39706.1 - 8.1e-05 22.6 0.4 0.37 10.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 OWF39706.1 - 0.00072 20.1 0.1 2.8 8.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 OWF39706.1 - 0.0017 18.4 3.7 0.094 12.8 0.0 3.1 4 0 0 4 4 3 1 Dynamin family AAA_23 PF13476.6 OWF39706.1 - 0.0022 18.5 3.4 1.1 9.7 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 OWF39706.1 - 0.0085 15.8 2.1 3.3 7.5 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 OWF39706.1 - 0.0088 16.2 0.7 0.036 14.2 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 OWF39706.1 - 0.015 15.6 5.3 1.4 9.2 0.1 3.1 3 1 0 3 3 2 0 AAA domain OstA_2 PF13100.6 OWF39706.1 - 0.022 14.4 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 OstA-like protein AAA_16 PF13191.6 OWF39706.1 - 0.036 14.4 1.3 9.2 6.6 0.7 3.0 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 OWF39706.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 OWF39706.1 - 0.042 13.1 0.6 4.5 6.5 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 OWF39706.1 - 0.065 12.2 0.4 6.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 OWF39706.1 - 0.073 13.2 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OWF39706.1 - 0.17 11.4 0.0 23 4.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OWF39706.1 - 0.17 10.7 0.6 4.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 OWF39706.1 - 0.18 11.0 0.6 15 4.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 OWF39706.1 - 0.23 10.6 1.8 4.9 6.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain ABC_tran PF00005.27 OWF39707.1 - 2.4e-20 73.5 0.0 5.9e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OWF39707.1 - 4.2e-07 29.9 26.6 3e-06 27.1 0.4 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region MeaB PF03308.16 OWF39707.1 - 0.0024 16.9 0.1 0.0038 16.2 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 OWF39707.1 - 0.022 14.2 0.1 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OWF39707.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 OWF39707.1 - 0.079 13.0 0.7 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 OWF39707.1 - 0.096 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 OWF39707.1 - 0.12 12.5 1.7 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.13 OWF39707.1 - 0.13 11.4 0.1 0.26 10.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 OWF39707.1 - 0.15 11.8 0.1 4.9 6.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system YpzI PF14140.6 OWF39708.1 - 0.32 10.8 14.3 33 4.4 0.2 5.3 5 0 0 5 5 5 0 YpzI-like protein ABC_tran PF00005.27 OWF39709.1 - 2.5e-31 109.0 0.0 4.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF39709.1 - 1.8e-07 30.9 0.3 0.00084 18.8 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.26 OWF39709.1 - 0.00038 20.2 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_21 PF13304.6 OWF39709.1 - 0.0007 19.5 0.1 0.26 11.0 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OWF39709.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DEAD PF00270.29 OWF39709.1 - 0.0026 17.6 1.7 0.032 14.0 1.7 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF87 PF01935.17 OWF39709.1 - 0.0035 17.5 0.3 0.005 17.0 0.3 1.5 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 OWF39709.1 - 0.014 15.6 0.5 0.14 12.5 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OWF39709.1 - 0.029 14.9 0.0 0.055 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OWF39709.1 - 0.033 14.7 0.1 0.071 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OWF39709.1 - 0.036 13.3 0.4 0.77 8.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 OWF39709.1 - 0.038 13.7 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 OWF39709.1 - 0.039 13.7 0.7 0.089 12.5 0.7 1.6 1 1 0 1 1 1 0 AAA domain FKBP_N_2 PF18023.1 OWF39709.1 - 0.061 13.4 0.2 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 BDBT FKBP like N-terminal RsgA_GTPase PF03193.16 OWF39709.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OWF39709.1 - 0.11 12.1 0.1 6.2 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OWF39709.1 - 0.19 11.5 0.0 0.56 10.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF39710.1 - 1.8e-53 180.8 0.0 2e-31 109.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OWF39710.1 - 7.5e-40 137.3 44.1 9.4e-29 100.9 13.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OWF39710.1 - 9e-12 44.9 1.4 0.014 14.8 0.1 4.6 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OWF39710.1 - 7.9e-07 29.2 0.5 1.7 8.4 0.0 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OWF39710.1 - 9.1e-07 29.0 0.5 0.05 13.7 0.0 3.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF39710.1 - 3.8e-06 26.9 0.0 0.042 13.7 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OWF39710.1 - 0.00045 20.6 0.1 1.2 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OWF39710.1 - 0.00069 19.3 0.2 1 9.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OWF39710.1 - 0.0011 19.5 5.3 0.54 10.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain MeaB PF03308.16 OWF39710.1 - 0.0014 17.7 0.0 0.27 10.2 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 OWF39710.1 - 0.0017 17.6 2.5 1.1 8.4 0.6 3.4 2 1 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 OWF39710.1 - 0.002 17.9 0.0 0.0098 15.6 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 OWF39710.1 - 0.0056 17.0 1.0 3 8.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OWF39710.1 - 0.006 16.7 2.6 0.64 10.1 0.1 3.1 3 0 0 3 3 3 1 Dynamin family AAA_7 PF12775.7 OWF39710.1 - 0.0068 15.9 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 OWF39710.1 - 0.0083 15.9 0.1 1.2 8.8 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF87 PF01935.17 OWF39710.1 - 0.012 15.8 0.6 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 OWF39710.1 - 0.014 14.6 0.1 3.6 6.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OWF39710.1 - 0.027 14.2 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OWF39710.1 - 0.054 12.8 0.9 13 5.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 OWF39710.1 - 0.057 13.1 0.4 2.9 7.5 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 OWF39710.1 - 0.06 13.9 0.4 22 5.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 OWF39711.1 - 3.8e-51 173.2 0.0 2.3e-30 105.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OWF39711.1 - 3.6e-27 95.7 45.8 4.1e-19 69.3 18.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OWF39711.1 - 2.4e-12 46.8 0.3 0.019 14.4 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OWF39711.1 - 1.2e-06 28.6 1.7 1.3 8.8 0.0 4.4 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OWF39711.1 - 1.9e-06 27.9 0.2 0.0037 17.2 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF39711.1 - 4.8e-06 26.6 0.1 0.0088 16.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OWF39711.1 - 0.00016 21.4 0.2 0.84 9.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 OWF39711.1 - 0.00041 20.5 0.0 0.0091 16.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain Sigma54_activat PF00158.26 OWF39711.1 - 0.0054 16.5 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 OWF39711.1 - 0.012 14.6 0.0 1.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 OWF39711.1 - 0.013 16.0 8.1 0.98 9.9 0.0 3.7 3 1 1 4 4 4 0 AAA domain NB-ARC PF00931.22 OWF39711.1 - 0.02 14.1 1.4 3.4 6.8 0.0 3.5 3 0 0 3 3 3 0 NB-ARC domain MeaB PF03308.16 OWF39711.1 - 0.025 13.6 0.1 4.4 6.2 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 OWF39711.1 - 0.036 13.6 0.1 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 OWF39711.1 - 0.038 14.3 1.5 6.5 7.0 0.2 3.5 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 OWF39711.1 - 0.06 13.4 5.7 0.83 9.7 0.2 3.2 3 0 0 3 3 3 0 Dynamin family AAA_24 PF13479.6 OWF39711.1 - 0.078 12.7 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OWF39711.1 - 0.1 11.9 0.1 15 4.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 OWF39711.1 - 0.16 12.3 0.4 6.6 7.1 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 OWF39711.1 - 0.46 10.1 3.6 4.6 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain COX7a PF02238.15 OWF39711.1 - 3.1 8.3 6.5 2.6 8.5 1.7 3.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Thioredox_DsbH PF03190.15 OWF39713.1 - 2.7e-73 245.3 0.0 5.7e-73 244.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 OWF39713.1 - 5.1e-09 36.2 0.2 1.3e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 OWF39713.1 - 6.2e-05 22.2 0.9 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 OWF39713.1 - 0.00032 20.3 2.4 0.011 15.2 0.1 2.7 3 0 0 3 3 3 1 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.11 OWF39713.1 - 0.0023 17.2 2.1 2.2 7.4 0.0 3.2 3 0 0 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 OWF39713.1 - 0.0061 16.1 6.8 0.53 9.7 0.8 3.3 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 OWF39713.1 - 0.011 14.3 1.1 1.8 6.9 0.2 2.8 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Pec_lyase PF09492.10 OWF39713.1 - 0.016 14.5 0.6 0.52 9.6 0.1 2.2 2 0 0 2 2 2 0 Pectic acid lyase LANC_like PF05147.13 OWF39713.1 - 0.017 13.7 0.0 0.22 10.1 0.0 2.5 3 0 0 3 3 3 0 Lanthionine synthetase C-like protein DUF4747 PF15931.5 OWF39714.1 - 0.0047 16.6 0.0 12 5.4 0.0 4.4 2 2 4 6 6 6 2 Domain of unknown function (DUF4747) APAF1_C PF17908.1 OWF39714.1 - 0.018 15.1 5.4 84 3.2 0.0 5.5 3 1 4 7 7 7 0 APAF-1 helical domain Methyltransf_20 PF12147.8 OWF39714.1 - 0.12 11.5 2.5 41 3.2 0.0 4.7 2 2 3 5 5 5 0 Putative methyltransferase PrcB_C PF14343.6 OWF39715.1 - 0.01 15.9 5.2 7.1 6.8 0.4 4.5 1 1 2 3 3 3 0 PrcB C-terminal P_proprotein PF01483.20 OWF39715.1 - 0.059 13.4 0.3 8.9 6.4 0.1 3.0 1 1 2 3 3 3 0 Proprotein convertase P-domain HigB_toxin PF09907.9 OWF39715.1 - 0.27 11.5 0.5 62 3.9 0.0 3.5 4 1 1 5 5 5 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system PAN_1 PF00024.26 OWF39715.1 - 0.32 11.0 8.7 1.3 9.0 3.6 2.5 1 1 1 2 2 2 0 PAN domain N_Asn_amidohyd PF14736.6 OWF39715.1 - 2.9 7.0 8.2 2.2 7.4 0.6 2.6 1 1 2 3 3 3 0 Protein N-terminal asparagine amidohydrolase Defensin_3 PF08131.11 OWF39715.1 - 5.3 7.3 5.9 67 3.8 0.1 4.1 3 1 0 4 4 4 0 Defensin-like peptide family DUF2282 PF10048.9 OWF39715.1 - 8.6 6.4 7.1 1e+02 3.0 0.1 4.4 2 1 4 6 6 6 0 Predicted integral membrane protein (DUF2282) PrcB_C PF14343.6 OWF39716.1 - 0.56 10.4 3.8 40 4.5 0.4 4.2 4 1 0 4 4 4 0 PrcB C-terminal Peptidase_C14 PF00656.22 OWF39717.1 - 5.2e-48 164.2 0.0 6.4e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Lipase_3 PF01764.25 OWF39718.1 - 2.4e-18 66.3 0.0 4.4e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OWF39718.1 - 0.02 15.5 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF39718.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 OWF39718.1 - 0.19 11.4 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Topoisom_bac PF01131.20 OWF39719.1 - 1.9e-116 389.5 0.0 2.8e-116 388.9 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 OWF39719.1 - 9.8e-32 108.8 17.6 2.5e-16 59.5 0.7 3.5 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 OWF39719.1 - 7.6e-18 64.6 0.1 1.9e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 OWF39719.1 - 1.7e-12 46.9 2.5 1.7e-12 46.9 2.5 3.8 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-FCS PF06467.14 OWF39720.1 - 0.077 12.9 7.1 0.22 11.5 1.2 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.6 OWF39720.1 - 0.2 12.6 9.2 2.2 9.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF39720.1 - 1.3 9.6 7.8 7.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type PyrI_C PF02748.15 OWF39720.1 - 4.4 7.3 6.1 2.7 8.0 0.3 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Peptidase_S10 PF00450.22 OWF39721.1 - 1.5e-80 271.6 0.5 1.8e-80 271.4 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Death PF00531.22 OWF39722.1 - 0.0076 16.4 0.1 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 Death domain DUF4987 PF16377.5 OWF39722.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Matrilin_ccoil PF10393.9 OWF39723.1 - 0.011 15.5 4.5 1.4 8.8 0.6 3.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.12 OWF39723.1 - 1.7 8.7 26.7 0.031 14.3 7.6 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) 7tm_1 PF00001.21 OWF39724.1 - 7.1e-18 64.9 22.7 9.4e-18 64.5 22.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF39724.1 - 1.4e-09 38.0 24.3 1.4e-09 38.0 24.3 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF39724.1 - 0.015 15.1 20.2 0.044 13.5 20.2 1.8 1 1 0 1 1 1 0 Olfactory receptor Lgl_C PF08596.10 OWF39725.1 - 2e-15 56.4 40.5 0.017 13.8 1.7 9.6 1 1 5 6 6 6 6 Lethal giant larvae(Lgl) like, C-terminal HECT PF00632.25 OWF39726.1 - 3.7e-88 295.9 1.9 5.7e-88 295.3 1.9 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 OWF39726.1 - 4e-84 277.1 25.1 4.2e-13 49.7 0.2 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF39726.1 - 1.4e-48 161.7 43.8 4.9e-11 42.1 0.9 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat MgtE_N PF03448.17 OWF39728.1 - 1.7e-05 25.3 0.1 18 6.0 0.0 4.2 1 1 0 3 3 3 2 MgtE intracellular N domain F-box-like_2 PF13013.6 OWF39728.1 - 0.0043 17.0 0.6 10 6.2 0.0 5.0 1 1 1 3 3 3 1 F-box-like domain Dev_Cell_Death PF10539.9 OWF39728.1 - 0.88 9.5 4.5 11 5.9 0.1 4.5 2 1 2 4 4 4 0 Development and cell death domain DUF2294 PF10057.9 OWF39728.1 - 2.5 8.2 32.1 36 4.5 0.1 7.7 1 1 12 13 13 13 0 Uncharacterized conserved protein (DUF2294) MucBP PF06458.12 OWF39729.1 - 7.3e-13 49.3 76.0 2.7e+02 2.6 4.7 18.6 1 1 2 3 3 3 0 MucBP domain DUF3724 PF12521.8 OWF39729.1 - 0.00031 20.4 56.1 40 4.4 0.1 29.9 41 0 0 41 41 41 1 Protein of unknown function (DUF3724) T3SS_ExsE PF18286.1 OWF39729.1 - 0.025 14.5 30.2 24 4.9 0.0 17.2 2 1 34 37 37 37 0 Type III secretion system ExsE zf-C3HC4 PF00097.25 OWF39731.1 - 8.9e-10 38.3 7.9 1.7e-09 37.4 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF39731.1 - 1.1e-08 35.0 5.5 2.1e-08 34.0 5.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF39731.1 - 2.5e-08 33.6 8.6 5.5e-08 32.5 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF39731.1 - 8.5e-08 32.2 9.1 1.8e-07 31.2 9.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF39731.1 - 1.2e-07 31.9 8.9 2.7e-07 30.8 8.9 1.6 1 0 0 1 1 1 1 Ring finger domain SAM_1 PF00536.30 OWF39731.1 - 1.7e-07 31.6 0.1 3.3e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF39731.1 - 8.2e-07 29.1 0.4 2.2e-06 27.7 0.2 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 OWF39731.1 - 6.5e-06 25.9 6.6 7.4e-06 25.7 5.6 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF39731.1 - 0.00039 20.3 7.1 0.00076 19.4 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OWF39731.1 - 0.0045 17.3 4.6 0.01 16.1 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF39731.1 - 0.0059 16.7 4.0 0.013 15.6 4.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OWF39731.1 - 0.024 14.5 6.5 0.05 13.5 6.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SAM_PNT PF02198.16 OWF39731.1 - 0.029 14.3 0.1 0.11 12.5 0.1 2.0 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-RING_4 PF14570.6 OWF39731.1 - 0.041 13.7 7.1 0.12 12.2 7.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1244 PF06844.11 OWF39731.1 - 0.13 12.4 3.2 0.62 10.3 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1244) zf-Nse PF11789.8 OWF39731.1 - 0.21 11.4 2.2 0.44 10.4 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OWF39731.1 - 0.27 11.3 2.4 0.6 10.2 2.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OWF39731.1 - 0.27 11.1 2.9 0.56 10.1 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 OWF39731.1 - 1.5 8.5 5.5 3.3 7.4 5.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CAF1 PF04857.20 OWF39732.1 - 2.6e-31 109.0 0.6 2.6e-31 109.0 0.6 1.8 2 0 0 2 2 2 1 CAF1 family ribonuclease RNA_bind PF08675.11 OWF39732.1 - 4.2e-26 90.8 0.1 8.5e-26 89.8 0.1 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.22 OWF39732.1 - 9.5e-06 25.5 0.3 3.3e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 R3H domain NCBP3 PF10309.9 OWF39732.1 - 0.038 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 RRM_1 PF00076.22 OWF39732.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ENTH PF01417.20 OWF39733.1 - 9.7e-14 51.5 0.9 1.7e-10 41.0 0.0 2.8 2 1 0 2 2 2 2 ENTH domain ANTH PF07651.16 OWF39733.1 - 1.2e-05 24.5 0.0 3.6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 ANTH domain adh_short_C2 PF13561.6 OWF39734.1 - 1.4e-52 178.6 0.1 1.6e-52 178.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF39734.1 - 1.1e-49 168.6 0.6 1.3e-49 168.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF39734.1 - 9.3e-13 48.5 0.3 1.3e-12 48.0 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF39734.1 - 8e-08 32.0 0.2 1.5e-06 27.9 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OWF39734.1 - 7.8e-05 22.6 0.3 0.0001 22.3 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OWF39734.1 - 0.0045 16.1 0.0 0.0093 15.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Shikimate_DH PF01488.20 OWF39734.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OWF39734.1 - 0.041 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TehB PF03848.14 OWF39734.1 - 0.071 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FAM220 PF15487.6 OWF39735.1 - 1.1e-79 267.9 0.0 1.8e-79 267.2 0.0 1.3 1 0 0 1 1 1 1 FAM220 family Ank_2 PF12796.7 OWF39735.1 - 3e-14 53.4 0.2 9.3e-09 35.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF39735.1 - 9e-13 47.2 0.3 0.0016 18.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OWF39735.1 - 2.4e-09 37.6 0.4 2e-07 31.4 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF39735.1 - 2.4e-09 37.2 0.8 0.0028 17.9 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF39735.1 - 8.4e-09 35.5 1.9 0.00036 20.8 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat DUF4597 PF15366.6 OWF39735.1 - 0.11 12.2 1.0 0.35 10.7 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) IgGFc_binding PF17517.2 OWF39736.1 - 3.7e-37 128.2 2.0 1.7e-35 122.8 0.2 2.0 2 0 0 2 2 2 2 IgGFc binding protein COesterase PF00135.28 OWF39737.1 - 7.8e-136 453.9 0.0 9.1e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39737.1 - 5.9e-10 39.4 0.3 3.6e-09 36.8 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OWF39738.1 - 1.3e-263 875.5 0.0 8.7e-131 437.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39738.1 - 1.2e-11 44.9 7.7 5.8e-05 23.0 1.2 3.4 2 2 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF39738.1 - 3.4e-06 26.7 1.9 0.046 13.2 0.3 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 OWF39738.1 - 0.00019 21.2 3.2 0.37 10.4 0.2 3.2 3 0 0 3 3 3 2 Putative esterase Say1_Mug180 PF10340.9 OWF39738.1 - 0.084 11.7 0.7 6.8 5.4 0.0 3.2 3 1 0 3 3 3 0 Steryl acetyl hydrolase Leader_Thr PF08254.11 OWF39738.1 - 0.11 12.3 0.9 0.42 10.4 0.9 2.1 1 0 0 1 1 1 0 Threonine leader peptide EBP PF05241.12 OWF39738.1 - 0.42 10.1 2.0 2.2 7.7 0.2 2.6 3 0 0 3 3 3 0 Emopamil binding protein CARD PF00619.21 OWF39740.1 - 1.4e-16 60.2 7.1 3.8e-10 39.6 4.5 2.4 2 0 0 2 2 2 2 Caspase recruitment domain Fer4_4 PF12800.7 OWF39741.1 - 1.8 9.3 14.0 0.67 10.6 4.7 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Peptidase_C26 PF07722.13 OWF39743.1 - 5.7e-19 68.7 0.0 2.2e-18 66.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 OWF39743.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PCMT PF01135.19 OWF39743.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BTB PF00651.31 OWF39744.1 - 1.2e-25 89.9 0.3 3.5e-25 88.4 0.3 1.9 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF39744.1 - 3.7e-22 78.4 1.4 1.2e-21 76.7 0.2 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 OWF39744.1 - 3e-12 46.4 0.2 7.9e-07 29.1 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 OWF39744.1 - 8e-10 38.2 1.7 0.0066 16.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 OWF39744.1 - 1.6e-08 34.3 0.2 0.00059 19.8 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 OWF39744.1 - 4.2e-05 23.5 0.0 0.0006 19.8 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF3342 PF11822.8 OWF39744.1 - 0.00081 19.5 1.1 0.0026 17.9 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Galactosyl_T PF01762.21 OWF39745.1 - 4.1e-44 150.7 0.0 5.4e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF39745.1 - 0.0046 16.4 0.3 0.0077 15.7 0.3 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF39746.1 - 1.7e-45 155.3 1.1 2.3e-45 154.8 0.2 1.6 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 OWF39746.1 - 0.0032 16.9 0.1 0.0076 15.7 0.1 1.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF39747.1 - 6.3e-45 153.4 0.5 8.4e-45 153.0 0.5 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF39747.1 - 0.00049 19.6 0.4 0.00098 18.6 0.4 1.5 1 1 0 1 1 1 1 Fringe-like IU_nuc_hydro PF01156.19 OWF39748.1 - 3.8e-27 95.7 0.0 4.6e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mod_r PF07200.13 OWF39749.1 - 3e-25 89.0 9.3 3e-25 89.0 9.3 1.6 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Death PF00531.22 OWF39750.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Death domain Ion_trans PF00520.31 OWF39752.1 - 3.3e-13 49.4 23.6 2.7e-12 46.4 23.6 2.0 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OWF39752.1 - 0.022 13.4 17.7 0.026 13.2 0.6 3.0 2 1 1 3 3 3 0 Polycystin cation channel LSDAT_euk PF18139.1 OWF39754.1 - 3.9e-39 134.6 0.0 4.2e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF39754.1 - 9.5e-17 60.9 0.1 1.2e-16 60.5 0.1 1.2 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote LSDAT_euk PF18139.1 OWF39756.1 - 1.7e-66 224.3 2.0 8.1e-65 218.9 2.0 2.4 1 1 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF39756.1 - 5.5e-25 87.8 0.7 3.8e-23 81.8 0.7 2.3 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 OWF39756.1 - 5.3e-14 52.0 22.6 1.5e-13 50.6 22.6 1.7 1 1 0 1 1 1 1 Ion transport protein Linker_histone PF00538.19 OWF39757.1 - 3e-25 88.4 1.5 3e-25 88.4 1.5 2.2 2 1 1 3 3 3 1 linker histone H1 and H5 family Forkhead PF00250.18 OWF39757.1 - 0.016 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Forkhead domain C1q PF00386.21 OWF39760.1 - 4.7e-21 75.3 0.2 7.2e-21 74.7 0.2 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF39760.1 - 1.6e-05 24.8 2.5 2.4e-05 24.2 2.5 1.2 1 0 0 1 1 1 1 BclA C-terminal domain YabA PF06156.13 OWF39760.1 - 0.005 17.5 0.2 0.0072 16.9 0.2 1.3 1 0 0 1 1 1 1 Initiation control protein YabA DivIC PF04977.15 OWF39760.1 - 0.013 15.3 0.2 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3847 PF12958.7 OWF39760.1 - 0.021 15.0 0.2 0.034 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) TauD PF02668.16 OWF39760.1 - 0.037 13.8 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family HWE_HK PF07536.14 OWF39760.1 - 0.038 14.7 0.2 0.061 14.0 0.2 1.3 1 0 0 1 1 1 0 HWE histidine kinase ZapB PF06005.12 OWF39760.1 - 0.064 13.7 1.6 0.1 13.1 1.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB ADIP PF11559.8 OWF39760.1 - 0.076 13.1 1.9 0.11 12.6 1.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TNF PF00229.18 OWF39760.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Rootletin PF15035.6 OWF39760.1 - 0.082 12.9 2.7 0.12 12.4 2.7 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.11 OWF39760.1 - 0.11 12.9 0.6 0.2 12.1 0.6 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 OWF39760.1 - 0.13 11.5 1.1 0.41 9.9 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 OWF39761.1 - 0.0061 16.6 1.3 0.019 15.0 1.3 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 OWF39761.1 - 0.1 12.9 0.3 7 7.0 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) YlbD_coat PF14071.6 OWF39761.1 - 0.11 12.7 0.8 9.1 6.6 0.1 3.2 1 1 2 3 3 3 0 Putative coat protein Transcrip_reg PF01709.20 OWF39762.1 - 0.13 11.7 0.6 0.14 11.5 0.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator Phage_Coat_A PF05357.13 OWF39762.1 - 5.7 6.8 11.2 52 3.7 0.7 4.8 1 1 3 4 4 4 0 Phage Coat Protein A ANTH PF07651.16 OWF39763.1 - 6.5e-64 215.6 0.0 6.5e-64 215.6 0.0 2.9 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 OWF39763.1 - 6.6e-52 175.8 9.5 6.6e-52 175.8 9.5 5.1 3 1 2 5 5 5 1 I/LWEQ domain DUF5082 PF16888.5 OWF39763.1 - 2.5e-05 24.6 14.1 2.5e-05 24.6 14.1 5.9 3 2 1 5 5 5 1 Domain of unknown function (DUF5082) ATG16 PF08614.11 OWF39763.1 - 0.13 12.4 82.4 0.031 14.5 21.5 6.8 3 2 3 6 6 6 0 Autophagy protein 16 (ATG16) DUF725 PF05267.12 OWF39763.1 - 9.8 6.2 8.9 2.4 8.1 3.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DUF4042 PF13251.6 OWF39764.1 - 5.6e-63 211.9 0.1 5.6e-63 211.9 0.1 3.9 6 0 0 6 6 6 1 Domain of unknown function (DUF4042) HEAT PF02985.22 OWF39764.1 - 8.3e-21 72.3 21.2 0.031 14.5 0.1 11.6 12 0 0 12 12 12 6 HEAT repeat HEAT_2 PF13646.6 OWF39764.1 - 4.9e-20 71.7 0.5 0.00014 22.2 0.0 8.2 5 1 3 8 8 8 6 HEAT repeats HEAT_EZ PF13513.6 OWF39764.1 - 1.7e-14 53.9 12.9 0.24 12.0 0.3 9.1 8 1 1 9 9 9 6 HEAT-like repeat Arm PF00514.23 OWF39764.1 - 2e-06 27.6 7.0 3.4 7.8 0.0 7.5 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 OWF39764.1 - 2.7e-06 27.5 12.2 0.25 11.4 0.1 6.9 6 2 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OWF39764.1 - 4.3e-06 26.9 0.2 0.73 10.0 0.1 5.0 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 OWF39764.1 - 0.016 13.8 0.1 0.016 13.8 0.1 3.8 4 1 1 5 5 5 0 Adaptin N terminal region IFS PF16718.5 OWF39764.1 - 0.031 14.4 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Immunity factor for SPN HEAT_PBS PF03130.16 OWF39764.1 - 2.3 9.2 6.9 29 5.7 0.0 5.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Ubie_methyltran PF01209.18 OWF39765.1 - 2.2e-89 298.8 0.0 1.7e-66 223.9 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OWF39765.1 - 3.4e-16 59.7 0.0 5.9e-14 52.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF39765.1 - 1e-15 58.1 0.0 3.4e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF39765.1 - 2.8e-11 43.4 0.0 9.7e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OWF39765.1 - 3.6e-07 30.8 0.0 1.9e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF39765.1 - 3.8e-07 30.1 0.0 8.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OWF39765.1 - 0.065 13.1 0.1 2.6 7.8 0.0 2.5 3 0 0 3 3 3 0 Hypothetical methyltransferase Dynein_light PF01221.18 OWF39766.1 - 1e-42 144.3 1.4 1.1e-42 144.2 1.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 OWF39766.1 - 0.036 13.8 0.2 0.047 13.5 0.2 1.2 1 0 0 1 1 1 0 Immunity protein 48 Peptidase_C3 PF00548.20 OWF39766.1 - 0.091 12.7 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Ectatomin PF06457.11 OWF39766.1 - 0.2 11.6 1.2 0.3 11.0 0.3 1.7 2 0 0 2 2 2 0 Ectatomin Dynein_light PF01221.18 OWF39767.1 - 7.2e-43 144.8 1.5 8.1e-43 144.7 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 OWF39768.1 - 5.7e-43 145.1 1.5 6.3e-43 145.0 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 OWF39768.1 - 0.17 11.8 0.3 0.3 11.0 0.3 1.4 1 0 0 1 1 1 0 Ectatomin Dynein_light PF01221.18 OWF39769.1 - 1.5e-41 140.6 1.4 1.8e-41 140.4 1.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 OWF39770.1 - 1.6e-40 137.3 0.7 1.8e-40 137.1 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 OWF39770.1 - 0.17 11.8 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Ectatomin Dynein_light PF01221.18 OWF39771.1 - 9.8e-43 144.4 1.8 9.8e-43 144.4 1.8 1.9 2 0 0 2 2 2 1 Dynein light chain type 1 Dynein_light PF01221.18 OWF39772.1 - 2e-43 146.6 1.6 2.2e-43 146.5 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 OWF39773.1 - 9e-33 111.9 0.0 5.1e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF39773.1 - 4.3e-08 33.1 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 OWF39773.1 - 0.0011 19.1 0.0 0.0047 17.0 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 OWF39773.1 - 0.0036 17.1 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RNA_bind PF08675.11 OWF39773.1 - 0.2 11.7 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 RNA binding domain RRM_1 PF00076.22 OWF39774.1 - 6.5e-33 112.4 0.0 6.9e-19 67.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF39774.1 - 4.4e-06 26.7 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 OWF39774.1 - 0.0008 19.5 0.0 0.0025 17.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 OWF39774.1 - 0.006 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OWF39774.1 - 0.04 13.9 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GRP PF07172.11 OWF39774.1 - 1 10.1 31.0 1.1 10.0 26.7 2.1 2 0 0 2 2 2 0 Glycine rich protein family Lipocalin PF00061.23 OWF39776.1 - 7.3e-11 42.5 1.8 8.1e-11 42.3 1.8 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4897 PF16238.5 OWF39776.1 - 0.018 14.9 0.8 0.022 14.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) DUF2209 PF09974.9 OWF39776.1 - 0.04 14.3 0.6 0.053 13.9 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Lipocalin PF00061.23 OWF39777.1 - 6.3e-07 29.7 0.2 8e-07 29.4 0.2 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family MFS_1 PF07690.16 OWF39778.1 - 8.5e-24 84.1 23.6 8.5e-24 84.1 23.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.15 OWF39778.1 - 1.1 8.2 23.5 0.12 11.4 8.2 2.0 1 1 1 2 2 2 0 PUCC protein I-set PF07679.16 OWF39779.1 - 7.7e-22 77.2 0.4 5.1e-11 42.5 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF39779.1 - 6.4e-21 74.7 0.5 4.9e-09 36.7 0.0 2.9 1 1 2 3 3 3 2 Immunoglobulin domain ig PF00047.25 OWF39779.1 - 1.7e-17 63.3 1.0 1.4e-08 34.8 0.3 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF39779.1 - 1.1e-14 54.5 1.1 1.7e-07 31.4 0.2 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF39779.1 - 1.8e-10 41.0 0.2 0.00059 20.1 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 OWF39779.1 - 2.8e-05 24.4 0.3 0.0043 17.4 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 OWF39779.1 - 5.2e-05 22.7 0.0 0.045 13.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 OWF39779.1 - 0.0024 17.9 0.2 0.62 10.2 0.1 2.6 2 1 0 2 2 2 2 Izumo-like Immunoglobulin domain PulA_N1 PF17999.1 OWF39779.1 - 0.21 12.4 0.9 6 7.7 0.1 2.9 2 1 1 3 3 3 0 Pullulanase N1-terminal domain Ribosomal_L40e PF01020.17 OWF39780.1 - 0.0025 17.6 27.1 46 4.0 0.1 10.1 2 1 8 11 11 11 0 Ribosomal L40e family Drc1-Sld2 PF11719.8 OWF39780.1 - 0.12 11.8 6.7 0.87 9.1 0.6 2.0 1 1 1 2 2 2 0 DNA replication and checkpoint protein Zfx_Zfy_act PF04704.13 OWF39780.1 - 0.13 11.4 6.0 3.3 6.8 2.7 2.8 1 1 1 2 2 2 0 Zfx / Zfy transcription activation region ecTbetaR2 PF08917.10 OWF39780.1 - 0.13 12.2 20.4 1.9 8.5 3.2 3.2 1 1 2 3 3 3 0 Transforming growth factor beta receptor 2 ectodomain DUF5447 PF17525.2 OWF39780.1 - 0.41 11.1 15.5 41 4.7 0.3 5.0 1 1 4 5 5 5 0 Family of unknown function (DUF5447) Ribosomal_L40e PF01020.17 OWF39781.1 - 0.00092 19.1 9.9 17 5.4 0.1 5.7 1 1 5 6 6 6 2 Ribosomal L40e family DUF4638 PF15472.6 OWF39781.1 - 0.0055 16.5 3.9 2.9 7.5 0.1 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4638) DUF4296 PF14129.6 OWF39781.1 - 0.048 14.3 7.1 0.18 12.4 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) Zfx_Zfy_act PF04704.13 OWF39781.1 - 0.06 12.5 1.2 1.6 7.8 0.4 2.0 1 1 1 2 2 2 0 Zfx / Zfy transcription activation region ecTbetaR2 PF08917.10 OWF39781.1 - 0.16 11.9 10.2 1.4 8.8 4.7 2.3 1 1 1 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain NEXCaM_BD PF16644.5 OWF39781.1 - 0.18 12.1 9.5 0.38 11.0 2.9 3.4 1 1 2 3 3 3 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Ig_3 PF13927.6 OWF39782.1 - 2.1e-19 69.9 0.1 2.3e-09 37.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF39782.1 - 2.3e-17 62.8 0.0 1.2e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 OWF39782.1 - 2.2e-16 59.8 0.1 7.5e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF39782.1 - 2e-12 47.2 0.2 4.2e-07 30.1 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF39782.1 - 2.5e-11 43.7 0.1 0.00027 21.2 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 OWF39782.1 - 0.0011 19.3 0.0 0.045 14.1 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 OWF39782.1 - 0.0014 18.9 0.2 2.6 8.5 0.0 3.6 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 OWF39782.1 - 0.0061 16.3 0.0 0.089 12.6 0.0 2.3 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 OWF39782.1 - 0.044 13.4 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin domain DUF4744 PF15918.5 OWF39783.1 - 0.0065 17.3 2.4 0.78 10.6 2.4 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4744) CBM32 PF18344.1 OWF39783.1 - 0.3 10.9 2.9 21 5.0 0.1 3.1 2 1 1 3 3 3 0 Carbohydrate binding module family 32 FOXO-TAD PF16676.5 OWF39783.1 - 4.7 7.7 7.6 1.6e+02 2.8 0.2 3.8 1 1 1 2 2 2 0 Transactivation domain of FOXO protein family TENA_THI-4 PF03070.16 OWF39785.1 - 9.5e-10 38.6 0.5 2.2e-09 37.4 0.5 1.7 1 1 0 1 1 1 1 TENA/THI-4/PQQC family TENA_THI-4 PF03070.16 OWF39786.1 - 1.2e-06 28.5 0.0 5.6e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Transglut_core PF01841.19 OWF39787.1 - 0.00017 22.0 0.0 0.00033 21.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily MT PF12777.7 OWF39787.1 - 0.00056 19.1 0.0 0.00088 18.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor MRP-S27 PF10037.9 OWF39788.1 - 3.5e-78 263.2 8.2 3.5e-78 263.2 8.2 1.3 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.6 OWF39788.1 - 0.00049 20.2 0.0 0.0088 16.2 0.0 3.1 3 0 0 3 3 3 1 PPR repeat family A_thal_3526 PF09713.10 OWF39788.1 - 0.065 13.5 1.4 0.79 10.0 0.4 2.9 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) PPR PF01535.20 OWF39788.1 - 0.13 12.5 0.0 55 4.3 0.0 3.4 3 0 0 3 3 3 0 PPR repeat TRPM_tetra PF16519.5 OWF39788.1 - 0.2 11.7 4.5 0.3 11.2 0.3 2.9 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Matrilin_ccoil PF10393.9 OWF39788.1 - 0.24 11.3 4.5 1 9.3 1.1 2.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4508 PF14969.6 OWF39788.1 - 8.4 6.7 10.2 1.1 9.5 4.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) HSP70 PF00012.20 OWF39789.1 - 2.4e-12 45.9 0.0 3.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.11 OWF39789.1 - 0.15 11.2 0.2 7.7 5.6 0.0 2.2 1 1 0 2 2 2 0 StbA protein ANF_receptor PF01094.28 OWF39791.1 - 6e-21 74.9 0.0 7.3e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF39791.1 - 0.0023 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 OWF39792.1 - 4e-24 85.4 0.0 4.4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF39792.1 - 0.0056 16.4 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein PGK PF00162.19 OWF39792.1 - 0.06 12.3 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase ANF_receptor PF01094.28 OWF39794.1 - 3.7e-23 82.2 0.0 4.6e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF39794.1 - 0.00035 20.4 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Lectin_C PF00059.21 OWF39795.1 - 1.3e-12 48.4 2.0 2.9e-12 47.3 2.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain MEIOC PF15189.6 OWF39795.1 - 0.016 14.8 0.3 0.025 14.2 0.3 1.2 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC UL45 PF05473.12 OWF39795.1 - 0.039 13.6 0.1 0.039 13.6 0.1 1.8 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF39795.1 - 0.18 11.1 1.2 0.2 10.9 0.1 1.6 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Guanylate_cyc PF00211.20 OWF39796.1 - 1.2e-68 230.4 0.0 4e-67 225.4 0.0 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 OWF39796.1 - 2.8e-66 224.0 0.1 7.2e-66 222.7 0.0 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 OWF39796.1 - 4.8e-36 124.4 0.0 7.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF39796.1 - 1.1e-31 110.2 0.0 2.4e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.6 OWF39796.1 - 1.4e-06 28.2 0.0 9.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein HNOBA PF07701.14 OWF39796.1 - 0.0051 16.3 0.5 0.0089 15.5 0.5 1.4 1 0 0 1 1 1 1 Heme NO binding associated DHquinase_II PF01220.19 OWF39796.1 - 0.12 12.1 0.0 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Dehydroquinase class II Sugar_tr PF00083.24 OWF39797.1 - 2e-125 419.2 19.1 2.4e-125 419.0 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39797.1 - 4.7e-22 78.4 29.3 4.7e-22 78.4 29.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FixQ PF05545.11 OWF39797.1 - 0.15 12.0 0.8 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ART PF01129.18 OWF39798.1 - 9.5e-08 31.6 0.5 1.3e-07 31.1 0.5 1.2 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase Ank_2 PF12796.7 OWF39799.1 - 2e-41 140.5 0.0 1.7e-17 63.8 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39799.1 - 1.3e-30 105.4 1.4 1.3e-10 41.6 0.1 6.3 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39799.1 - 7.4e-26 87.4 1.2 4.1e-05 23.7 0.1 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 OWF39799.1 - 1.4e-25 88.5 1.4 1.6e-05 25.1 0.0 8.9 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 OWF39799.1 - 5.5e-21 74.4 0.4 8.8e-07 29.1 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) DUF1647 PF07801.11 OWF39800.1 - 4.4e-10 39.4 0.1 1.2e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) 7tm_1 PF00001.21 OWF39801.1 - 8.8e-14 51.5 14.7 1.2e-13 51.0 14.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF39801.1 - 0.00063 19.4 17.6 0.00086 19.0 17.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 OWF39801.1 - 0.41 9.8 14.3 0.57 9.3 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Peptidase_C2 PF00648.21 OWF39802.1 - 1.3e-118 395.3 0.6 2.1e-118 394.7 0.6 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF39802.1 - 3.5e-32 111.6 0.1 6e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 OWF39802.1 - 5e-12 46.0 0.4 4.3e-11 43.0 0.1 2.3 2 0 0 2 2 2 1 C2 domain Toxin_31 PF08119.11 OWF39802.1 - 0.22 11.3 1.4 0.48 10.2 1.4 1.5 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family Ribosomal_L35Ae PF01247.18 OWF39803.1 - 2.2e-44 149.5 0.4 2.6e-44 149.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OWF39803.1 - 0.015 15.5 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain CENP-M PF11111.8 OWF39803.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) IQ PF00612.27 OWF39804.1 - 1.5e-05 24.4 0.6 5.8e-05 22.5 0.6 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif TIMELESS_C PF05029.13 OWF39805.1 - 1.4e-08 34.4 0.0 7.4e-06 25.4 0.1 2.2 2 0 0 2 2 2 2 Timeless protein C terminal region TIMELESS PF04821.14 OWF39805.1 - 2.8e-07 30.1 1.1 8.6e-07 28.5 1.1 1.8 1 0 0 1 1 1 1 Timeless protein B PF02216.16 OWF39805.1 - 0.026 14.5 1.2 1.4 9.0 1.2 2.7 2 0 0 2 2 2 0 B domain Galactosyl_T PF01762.21 OWF39806.1 - 1.6e-33 116.2 0.1 2.4e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase PRELI PF04707.14 OWF39806.1 - 0.0033 17.2 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 PRELI-like family Fringe PF02434.16 OWF39806.1 - 0.012 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 OWF39808.1 - 6.4e-31 107.7 0.1 2e-30 106.1 0.1 1.7 2 0 0 2 2 2 1 Galactosyltransferase Noggin PF05806.12 OWF39808.1 - 0.077 12.9 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 Noggin Galactosyl_T PF01762.21 OWF39809.1 - 2.2e-36 125.5 2.0 2.8e-36 125.2 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 OWF39809.1 - 0.0014 18.1 0.1 0.0014 18.1 0.1 1.7 2 1 0 2 2 2 1 Fringe-like Lig_chan PF00060.26 OWF39811.1 - 1.3e-26 93.2 0.1 1.9e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF39811.1 - 1.8e-25 89.3 0.0 7.5e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF39811.1 - 1.1e-11 44.6 0.0 2.2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 OWF39811.1 - 0.014 15.3 0.7 0.014 15.3 0.7 2.8 3 0 0 3 3 3 0 Ion channel Lig_chan-Glu_bd PF10613.9 OWF39812.1 - 4.1e-26 91.4 0.0 1.1e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 OWF39812.1 - 9.2e-26 90.5 0.1 1.9e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OWF39812.1 - 3.6e-16 59.3 0.0 6.4e-16 58.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SAP130_C PF16014.5 OWF39813.1 - 3.5e-51 174.6 5.5 3.5e-51 174.6 5.5 5.7 3 2 3 6 6 6 2 Histone deacetylase complex subunit SAP130 C-terminus Phage_coat PF09063.10 OWF39813.1 - 0.1 12.6 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Phage PP7 coat protein FlgM PF04316.13 OWF39813.1 - 1.4 9.3 3.4 0.98 9.8 0.2 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM zf-C2H2_4 PF13894.6 OWF39814.1 - 0.0026 18.4 42.4 0.11 13.4 3.6 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OWF39814.1 - 0.0027 18.4 2.1 0.0027 18.4 2.1 4.0 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C4_ClpX PF06689.13 OWF39814.1 - 5.9 6.9 6.8 2.7 7.9 0.9 2.9 2 0 0 2 2 2 0 ClpX C4-type zinc finger Pkinase PF00069.25 OWF39816.1 - 1.8e-61 207.8 0.0 3.5e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Guanylate_kin PF00625.21 OWF39816.1 - 6.7e-57 192.1 0.0 1.2e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Pkinase_Tyr PF07714.17 OWF39816.1 - 1.6e-23 83.3 0.0 4.5e-22 78.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.24 OWF39816.1 - 3.5e-15 56.1 0.3 7.8e-15 55.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 OWF39816.1 - 1.6e-14 53.4 6.4 4.8e-07 29.4 0.2 4.1 4 0 0 4 4 4 2 L27 domain SH3_1 PF00018.28 OWF39816.1 - 3.4e-07 29.8 0.2 1.6e-06 27.6 0.2 2.1 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF39816.1 - 2.6e-05 23.8 0.0 6.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 OWF39816.1 - 0.0074 16.1 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF39816.1 - 0.0091 16.3 0.0 0.031 14.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 OWF39816.1 - 0.025 14.4 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Kdo PF06293.14 OWF39816.1 - 0.082 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GDP_Man_Dehyd PF16363.5 OWF39817.1 - 1.6e-56 192.1 0.0 3.9e-56 190.9 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OWF39817.1 - 4.6e-50 170.3 0.0 6.2e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OWF39817.1 - 9.6e-11 41.3 0.1 4.5e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OWF39817.1 - 6.9e-09 35.2 0.0 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OWF39817.1 - 2.1e-08 33.5 0.0 4.3e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OWF39817.1 - 4.4e-08 32.6 0.4 0.00059 19.1 0.2 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein TrkA_N PF02254.18 OWF39817.1 - 0.016 15.4 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain CdvA PF18822.1 OWF39817.1 - 0.051 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Ribosomal_S22 PF08136.11 OWF39817.1 - 0.12 12.7 0.2 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 30S ribosomal protein subunit S22 family adh_short PF00106.25 OWF39817.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF2459 PF09601.10 OWF39818.1 - 0.47 10.2 4.8 0.88 9.4 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2459) EHN PF06441.12 OWF39818.1 - 4 7.9 9.7 1.6 9.2 0.4 2.6 1 1 0 2 2 2 0 Epoxide hydrolase N terminus DDHD PF02862.17 OWF39818.1 - 4.6 7.4 9.4 3.2 7.9 7.9 1.4 1 1 0 1 1 1 0 DDHD domain Ras PF00071.22 OWF39820.1 - 7.1e-51 172.0 0.1 1e-50 171.5 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF39820.1 - 5.7e-28 97.5 0.1 5.7e-28 97.5 0.1 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF39820.1 - 8e-15 54.7 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF39820.1 - 1.1e-07 31.9 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF39820.1 - 0.00047 19.6 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OWF39820.1 - 0.0014 18.5 0.0 0.02 14.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OWF39820.1 - 0.0032 17.4 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OWF39820.1 - 0.004 16.6 0.0 0.0084 15.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 OWF39820.1 - 0.023 14.0 0.0 0.067 12.5 0.0 1.8 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 OWF39820.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OWF39820.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DOMON PF03351.17 OWF39820.1 - 0.29 11.3 2.4 0.28 11.4 0.3 2.0 2 1 1 3 3 3 0 DOMON domain Roc PF08477.13 OWF39821.1 - 1.7e-14 54.1 0.0 9.3e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF39821.1 - 7.6e-10 38.6 0.1 1.1e-06 28.3 0.0 2.6 2 1 1 3 3 3 2 Ras family Arf PF00025.21 OWF39821.1 - 8.8e-06 25.3 0.2 0.029 13.8 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Ank_4 PF13637.6 OWF39821.1 - 0.00022 21.7 1.8 0.18 12.4 0.0 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) PduV-EutP PF10662.9 OWF39821.1 - 0.0012 18.6 0.2 0.0044 16.8 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Ank_2 PF12796.7 OWF39821.1 - 0.0024 18.4 0.1 0.0053 17.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Gtr1_RagA PF04670.12 OWF39821.1 - 0.004 16.5 0.5 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF39821.1 - 0.0067 16.5 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF39821.1 - 0.0097 15.8 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 OWF39821.1 - 0.0097 15.6 0.0 0.03 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF39821.1 - 0.018 15.3 0.1 0.85 9.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OWF39821.1 - 0.031 14.4 0.0 0.097 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OWF39821.1 - 0.064 13.8 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ank_3 PF13606.6 OWF39821.1 - 0.091 13.4 0.3 1.6e+02 3.4 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat AAA PF00004.29 OWF39821.1 - 0.093 13.2 0.0 2.5 8.6 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Death PF00531.22 OWF39822.1 - 7.7e-14 51.6 0.4 1.9e-05 24.7 0.0 2.8 3 0 0 3 3 3 2 Death domain HP_OMP PF01856.17 OWF39822.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein DUF2130 PF09903.9 OWF39822.1 - 0.14 11.4 0.7 0.23 10.7 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) VWA PF00092.28 OWF39823.1 - 9.5e-37 126.9 0.7 2.3e-36 125.7 0.7 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain SEA PF01390.20 OWF39823.1 - 3.1e-16 59.4 4.9 1.3e-12 47.8 0.4 3.4 3 0 0 3 3 3 2 SEA domain VWA_2 PF13519.6 OWF39823.1 - 2.9e-13 50.4 0.0 8.1e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF39823.1 - 0.0004 20.4 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF39823.1 - 8.1 5.8 7.2 0.41 10.0 0.5 2.1 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein PAS_11 PF14598.6 OWF39824.1 - 2.3e-17 63.1 0.0 3.6e-14 52.8 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 OWF39824.1 - 1.9e-11 44.1 0.0 2.6e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold Period_C PF12114.8 OWF39824.1 - 3.4e-10 39.8 11.4 7e-07 29.0 0.3 3.5 3 0 0 3 3 3 2 Period protein 2/3C-terminal region PAS PF00989.25 OWF39824.1 - 1.7e-06 28.0 0.0 1.9e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_2 PF08446.11 OWF39824.1 - 0.031 15.0 0.1 0.24 12.1 0.0 2.4 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 OWF39824.1 - 0.038 14.2 0.0 6.9 7.0 0.0 2.8 2 0 0 2 2 2 0 PAS domain eIF-5a PF01287.20 OWF39825.1 - 3.2e-26 91.2 0.4 5.6e-26 90.4 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OWF39825.1 - 0.0018 18.3 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain SRCR PF00530.18 OWF39826.1 - 1.1e-62 208.8 19.5 4.8e-32 110.4 2.5 3.3 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF39826.1 - 1e-15 58.0 8.8 9.4e-07 29.3 0.1 3.5 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF39826.1 - 4.1e-06 27.3 1.8 0.075 13.6 0.0 3.0 3 0 0 3 3 3 2 Hepsin, SRCR domain Fucokinase PF07959.12 OWF39826.1 - 0.0008 18.5 2.7 0.13 11.2 0.3 2.2 2 0 0 2 2 2 2 L-fucokinase REGB_T4 PF10715.9 OWF39826.1 - 0.0068 16.6 0.0 0.71 10.1 0.0 2.4 2 0 0 2 2 2 1 T4-page Endoribonuclease RegB Neocarzinostat PF00960.18 OWF39826.1 - 0.015 15.2 21.6 0.48 10.4 1.5 2.7 2 0 0 2 2 2 0 Neocarzinostatin family GPR15L PF15854.5 OWF39826.1 - 0.2 11.9 1.1 1.1 9.6 1.4 2.1 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 MT PF12777.7 OWF39827.1 - 2.3e-07 30.2 0.1 2.6e-07 30.0 0.1 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor PAN_1 PF00024.26 OWF39830.1 - 1.6e-05 24.8 3.5 1.6e-05 24.8 3.5 1.7 1 1 1 2 2 2 1 PAN domain Sugar_tr PF00083.24 OWF39831.1 - 8.3e-129 430.4 17.0 9.8e-129 430.1 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39831.1 - 7.5e-22 77.7 18.8 7.5e-22 77.7 18.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DoxX_3 PF13781.6 OWF39831.1 - 0.46 11.1 4.6 2.1 9.1 1.5 2.7 2 0 0 2 2 2 0 DoxX-like family Ank_2 PF12796.7 OWF39833.1 - 3.2e-24 85.3 4.4 1.1e-13 51.6 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39833.1 - 2.6e-19 69.3 4.8 1.6e-10 41.3 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39833.1 - 6.6e-11 41.5 0.1 0.007 16.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OWF39833.1 - 1.3e-10 41.2 0.6 0.00093 19.5 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OWF39833.1 - 1.6e-09 37.8 0.4 7.2e-07 29.4 0.1 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ribosomal_L25p PF01386.19 OWF39833.1 - 0.053 14.0 0.5 0.17 12.4 0.1 2.1 2 0 0 2 2 2 0 Ribosomal L25p family DNA_ligase_A_M PF01068.21 OWF39834.1 - 8.4e-59 198.6 0.0 1.7e-58 197.6 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OWF39834.1 - 1e-31 110.6 1.4 2.1e-31 109.6 1.4 1.6 1 0 0 1 1 1 1 DNA ligase N terminus zf-PARP PF00645.18 OWF39834.1 - 1.1e-21 77.5 0.3 4.3e-21 75.6 0.1 2.3 2 0 0 2 2 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region LIG3_BRCT PF16759.5 OWF39834.1 - 1.1e-19 70.4 0.0 2.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain DNA_ligase_A_C PF04679.15 OWF39834.1 - 1e-16 61.3 0.1 3.8e-16 59.5 0.0 2.1 2 0 0 2 2 1 1 ATP dependent DNA ligase C terminal region zf-CCHH PF10283.9 OWF39834.1 - 1.5e-10 40.9 1.4 1.5e-10 40.9 1.4 2.2 2 0 0 2 2 2 1 PBZ domain BRCT_2 PF16589.5 OWF39834.1 - 1.9e-07 31.4 0.1 2.2e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 OWF39834.1 - 1.9e-06 28.3 0.1 3.9e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 OWF39834.1 - 0.0033 17.3 0.6 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain RasGAP_C PF03836.15 OWF39834.1 - 0.18 11.9 1.9 0.44 10.7 0.0 2.6 3 0 0 3 3 3 0 RasGAP C-terminus Pneumo_att_G PF05539.11 OWF39834.1 - 5.1 6.6 12.3 11 5.4 12.3 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SPRY PF00622.28 OWF39835.1 - 4.9e-18 65.4 0.0 8.5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 OWF39835.1 - 8.1e-11 42.1 2.5 1.3e-10 41.4 2.5 1.3 1 0 0 1 1 1 1 SOCS box RhoGEF PF00621.20 OWF39836.1 - 3.2e-32 112.3 1.7 4e-32 111.9 0.1 2.0 2 1 0 2 2 2 1 RhoGEF domain Reg_prop PF07494.11 OWF39836.1 - 0.071 13.4 0.3 0.96 9.9 0.1 3.0 2 0 0 2 2 2 0 Two component regulator propeller CHZ PF09649.10 OWF39836.1 - 0.24 10.9 5.1 1.3 8.6 1.0 2.4 2 0 0 2 2 2 0 Histone chaperone domain CHZ Casein PF00363.18 OWF39836.1 - 1.3 9.5 6.1 0.16 12.3 0.2 2.6 4 0 0 4 4 4 0 Casein PID PF00640.23 OWF39837.1 - 5.5e-13 49.1 0.4 1.9e-12 47.4 0.4 1.9 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 OWF39837.1 - 3.1e-12 46.4 0.0 1.3e-11 44.4 0.0 2.2 1 0 0 1 1 1 1 SH2 domain PID_2 PF14719.6 OWF39837.1 - 0.00081 19.3 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) UCH PF00443.29 OWF39838.1 - 3.9e-46 157.6 0.0 8.3e-46 156.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 OWF39838.1 - 7.8e-27 92.8 1.1 5.9e-13 48.4 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 OWF39838.1 - 6.7e-25 86.6 4.0 7.8e-23 80.0 0.1 3.5 4 0 0 4 4 4 2 Variant UBP zinc finger zf-UBP PF02148.19 OWF39838.1 - 4.5e-17 62.1 0.0 2.4e-16 59.8 0.0 2.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OWF39838.1 - 3e-09 36.9 1.2 0.00042 20.0 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 OWF39838.1 - 0.0027 17.5 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain RAC_head PF16717.5 OWF39839.1 - 0.17 12.9 0.8 0.28 12.2 0.3 1.5 2 0 0 2 2 2 0 Ribosome-associated complex head domain GLTP PF08718.11 OWF39840.1 - 9.1e-41 139.6 1.2 3.5e-40 137.7 0.0 1.9 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) DUF2083 PF09856.9 OWF39840.1 - 0.093 12.6 0.0 3.5 7.4 0.0 2.2 1 1 1 2 2 2 0 Predicted transcriptional regulator (DUF2083) Adap_comp_sub PF00928.21 OWF39841.1 - 1.6e-80 270.3 0.1 2.1e-80 269.9 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OWF39841.1 - 9.4e-08 32.1 0.9 1.5e-07 31.4 0.9 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L22e PF01776.17 OWF39842.1 - 1.3e-48 163.9 3.8 1.8e-48 163.4 3.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ATG19_autophagy PF12744.7 OWF39843.1 - 0.029 13.6 3.5 0.047 12.9 3.5 1.3 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Noc2 PF03715.13 OWF39844.1 - 8e-120 399.6 7.2 8e-120 399.6 7.2 1.8 3 0 0 3 3 3 1 Noc2p family Hid1 PF12722.7 OWF39844.1 - 0.00046 18.5 12.0 0.00095 17.4 12.0 1.5 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Nop14 PF04147.12 OWF39844.1 - 0.014 13.6 0.2 0.014 13.6 0.2 4.4 3 1 0 3 3 3 0 Nop14-like family dCMP_cyt_deam_1 PF00383.23 OWF39845.1 - 2.3e-17 62.7 0.3 2.7e-17 62.5 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OWF39845.1 - 4.8e-10 39.8 0.1 1.3e-09 38.3 0.1 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OWF39845.1 - 0.23 11.0 1.3 12 5.4 0.1 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases NAD_kinase PF01513.21 OWF39846.1 - 1.9e-66 224.3 0.0 3.2e-66 223.5 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OWF39846.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_39 PF01229.17 OWF39847.1 - 4.7e-91 305.8 1.1 7.3e-90 301.9 1.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Ank_2 PF12796.7 OWF39848.1 - 4.2e-59 197.1 0.3 4e-17 62.6 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39848.1 - 2.6e-40 136.3 0.9 9.4e-12 45.2 0.0 6.4 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF39848.1 - 3.9e-39 132.2 4.3 7.1e-08 32.6 0.1 7.9 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39848.1 - 1.2e-27 92.9 0.1 0.00019 21.6 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 OWF39848.1 - 2.3e-25 87.8 3.5 0.0018 18.7 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat DUF3447 PF11929.8 OWF39848.1 - 0.013 15.5 0.0 14 5.8 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Phostensin_N PF13916.6 OWF39848.1 - 0.036 14.4 1.0 0.036 14.4 1.0 3.0 2 1 1 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal DRY_EERY PF09750.9 OWF39848.1 - 0.05 13.9 1.9 0.12 12.7 1.9 1.5 1 0 0 1 1 1 0 Alternative splicing regulator Alk_phosphatase PF00245.20 OWF39849.1 - 5.9e-137 457.0 0.5 6.8e-137 456.8 0.5 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF39849.1 - 3e-05 23.5 0.0 4.1e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OWF39849.1 - 0.0042 16.5 1.2 0.36 10.2 0.2 2.7 1 1 1 2 2 2 2 Sulfatase UQ_con PF00179.26 OWF39850.1 - 1.7e-19 69.9 0.0 2.7e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FSAP_sig_propep PF03032.15 OWF39850.1 - 0.08 13.0 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF368 PF04018.13 OWF39851.1 - 0.18 11.3 2.9 0.31 10.6 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) TetR PF13972.6 OWF39851.1 - 0.91 9.2 8.8 3.2 7.4 0.9 2.9 2 1 0 3 3 3 0 Bacterial transcriptional repressor SAM35 PF10806.8 OWF39852.1 - 0.031 14.5 0.1 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 SAM35, subunit of SAM coomplex PH PF00169.29 OWF39853.1 - 2.8e-09 37.4 0.2 5.3e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OWF39853.1 - 0.002 18.3 0.8 0.01 16.1 0.8 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain SAM35 PF10806.8 OWF39853.1 - 0.017 15.4 0.3 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 SAM35, subunit of SAM coomplex PH_9 PF15410.6 OWF39853.1 - 0.031 14.6 4.3 31 4.9 0.0 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 OWF39853.1 - 0.082 13.3 5.5 9.5 6.7 2.4 2.8 1 1 1 2 2 2 0 Pleckstrin homology domain Phage_Gp17 PF17549.2 OWF39853.1 - 0.69 9.9 3.0 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 Gene Product 17 ELFV_dehydrog_N PF02812.18 OWF39854.1 - 0.007 16.2 9.0 0.26 11.2 2.9 3.2 1 1 1 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain UCR_UQCRX_QCR9 PF05365.12 OWF39854.1 - 2.2 8.3 19.3 3.9 7.5 0.4 4.6 2 2 2 4 4 4 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like TilS_C PF11734.8 OWF39855.1 - 0.0015 18.0 3.0 13 5.3 0.1 4.7 4 1 0 4 4 4 3 TilS substrate C-terminal domain TIP39 PF14980.6 OWF39855.1 - 0.14 12.1 0.4 2.1e+02 1.9 0.0 4.9 6 0 0 6 6 6 0 TIP39 peptide DUF5500 PF17604.2 OWF39855.1 - 2.8 8.1 15.8 0.93 9.6 0.1 5.9 3 2 2 6 6 6 0 Family of unknown function (DUF5500) E3_UbLigase_RBR PF18091.1 OWF39855.1 - 4.1 7.6 5.7 62 3.8 0.0 4.5 1 1 3 6 6 6 0 E3 Ubiquitin Ligase RBR C-terminal domain Lipocalin_2 PF08212.12 OWF39856.1 - 1.7e-23 83.2 0.0 2.2e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF39856.1 - 5.9e-19 68.7 0.2 8.6e-19 68.2 0.2 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 OWF39856.1 - 0.0038 16.8 0.4 0.0051 16.4 0.4 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Triabin PF03973.13 OWF39856.1 - 0.048 13.5 0.4 0.19 11.6 0.0 2.0 2 1 0 2 2 2 0 Triabin VWD PF00094.25 OWF39858.1 - 2e-10 41.2 2.4 4.8e-10 39.9 2.4 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain SbmA_BacA PF05992.12 OWF39859.1 - 0.044 13.2 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 SbmA/BacA-like family Phage_holin_2_4 PF16082.5 OWF39859.1 - 0.058 13.1 0.2 0.081 12.7 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Ank_2 PF12796.7 OWF39860.1 - 1.9e-40 137.3 1.3 5.1e-17 62.2 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39860.1 - 3e-24 85.0 0.0 2e-09 37.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39860.1 - 5.2e-21 72.5 0.1 7.6e-05 22.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OWF39860.1 - 4e-20 71.3 0.9 3.3e-06 27.3 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OWF39860.1 - 1.5e-18 66.6 0.0 1.8e-06 28.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) CDH-cyt PF16010.5 OWF39861.1 - 0.1 12.3 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase 7tm_1 PF00001.21 OWF39862.1 - 3.4e-41 141.3 18.7 4.2e-41 141.0 18.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF39862.1 - 2.6e-07 30.6 19.9 3.1e-07 30.3 19.9 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF39862.1 - 0.0093 15.7 12.5 0.013 15.2 12.5 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF39862.1 - 0.12 11.7 18.7 0.16 11.3 18.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx WD40_3 PF15911.5 OWF39863.1 - 0.0002 21.3 12.1 2.7 8.1 0.3 4.9 1 1 4 5 5 5 4 WD domain, G-beta repeat Herpes_UL31 PF02718.14 OWF39863.1 - 0.56 9.1 10.8 32 3.4 0.5 5.1 1 1 5 6 6 6 0 Herpesvirus UL31-like protein Ribosom_S12_S23 PF00164.25 OWF39863.1 - 1.4 8.5 6.9 27 4.4 0.3 3.7 1 1 3 4 4 4 0 Ribosomal protein S12/S23 PA-IIL PF07472.11 OWF39863.1 - 3.7 7.9 8.2 91 3.4 0.4 4.3 1 1 4 5 5 5 0 Fucose-binding lectin II (PA-IIL) TSP_1 PF00090.19 OWF39864.1 - 0.97 9.7 17.4 23 5.3 3.0 4.0 2 1 2 4 4 4 0 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF39865.1 - 0.00016 22.2 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF39865.1 - 0.00024 21.4 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Orthopox_A43R PF06517.11 OWF39865.1 - 0.0063 16.3 1.5 0.0087 15.9 1.5 1.3 1 1 0 1 1 1 1 Orthopoxvirus A43R protein ig PF00047.25 OWF39865.1 - 0.18 12.0 0.0 3.1 8.0 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin domain TsaE PF02367.17 OWF39865.1 - 0.19 11.8 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ubie_methyltran PF01209.18 OWF39866.1 - 6.5e-05 22.4 0.3 23 4.2 0.0 5.4 1 1 8 9 9 9 8 ubiE/COQ5 methyltransferase family I-set PF07679.16 OWF39867.1 - 5e-56 186.7 6.9 3.8e-17 62.1 0.0 5.9 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF39867.1 - 3.6e-55 184.5 7.2 5.7e-16 58.9 0.0 6.4 7 0 0 7 7 6 5 Immunoglobulin domain Ig_2 PF13895.6 OWF39867.1 - 3.3e-39 133.1 8.0 3e-10 40.3 0.0 6.2 5 2 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 OWF39867.1 - 2.3e-35 120.6 10.3 2.6e-09 37.1 0.2 5.5 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 OWF39867.1 - 9.1e-23 80.5 15.1 7.1e-08 32.6 0.1 7.5 7 2 1 8 8 8 4 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF39867.1 - 7e-11 42.2 2.8 0.54 10.6 0.0 6.3 6 1 1 7 7 5 2 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.21 OWF39867.1 - 1.2e-08 35.1 5.1 6.2e-07 29.7 0.7 3.6 3 0 0 3 3 3 1 Fibronectin type III domain C2-set_2 PF08205.12 OWF39867.1 - 7.4e-07 29.1 3.6 2.8 8.1 0.0 5.0 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 OWF39867.1 - 8.2e-07 28.5 1.0 8.5e-05 22.0 0.0 3.4 4 0 0 4 4 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 OWF39867.1 - 6e-06 26.2 0.0 0.13 12.4 0.0 3.8 4 0 0 4 4 3 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 OWF39867.1 - 0.0007 19.9 8.0 0.46 10.9 0.0 5.7 5 2 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 OWF39867.1 - 0.007 16.5 0.0 1.9 8.7 0.0 3.1 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Pur_ac_phosph_N PF16656.5 OWF39867.1 - 0.022 15.3 3.4 0.36 11.4 0.1 3.2 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Adeno_E3_CR1 PF02440.15 OWF39867.1 - 0.022 14.5 4.4 1 9.2 0.4 3.8 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 OWF39867.1 - 0.042 13.8 1.1 7.1 6.6 0.0 4.2 3 1 1 4 4 4 0 CD47 immunoglobulin-like domain ACAS_N PF16177.5 OWF39867.1 - 0.098 12.6 0.1 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Collagen PF01391.18 OWF39868.1 - 1.1e-18 66.7 48.8 0.19 11.5 48.8 2.8 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Tup_N PF08581.10 OWF39868.1 - 0.079 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Tup N-terminal DivIVA PF05103.13 OWF39868.1 - 0.16 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 DivIVA protein C1q PF00386.21 OWF39869.1 - 6e-21 75.0 0.1 8e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF39869.1 - 0.012 15.5 0.2 0.019 14.9 0.2 1.4 1 1 0 1 1 1 0 BclA C-terminal domain Sclerostin PF05463.11 OWF39870.1 - 5.7e-30 104.5 11.9 7.3e-30 104.2 11.9 1.1 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 OWF39870.1 - 1.5e-10 41.1 4.3 3.1e-10 40.1 4.3 1.5 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 OWF39870.1 - 0.0022 18.3 6.9 0.0022 18.3 6.9 2.1 2 1 0 2 2 2 1 Cystine-knot domain zf-RING_UBOX PF13445.6 OWF39872.1 - 5.4e-09 35.9 6.6 5.4e-09 35.9 6.6 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF39872.1 - 1.5e-06 28.0 10.4 1.5e-06 28.0 10.4 4.1 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF39872.1 - 2.5e-06 27.3 8.3 2.5e-06 27.3 8.3 4.1 2 1 1 3 3 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF39872.1 - 9.2e-06 25.9 9.5 9.2e-06 25.9 9.5 4.1 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF39872.1 - 1e-05 25.3 8.8 1e-05 25.3 8.8 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF39872.1 - 3.5e-05 23.9 12.1 3.5e-05 23.9 12.1 3.4 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF39872.1 - 0.0033 17.2 9.1 0.0033 17.2 9.1 3.6 3 1 0 3 3 1 1 Prokaryotic RING finger family 4 SBBP PF06739.11 OWF39872.1 - 0.0039 17.2 0.2 0.0087 16.0 0.2 1.6 1 0 0 1 1 1 1 Beta-propeller repeat DUF1722 PF08349.11 OWF39872.1 - 0.0042 17.4 1.2 0.0093 16.2 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) SGL PF08450.12 OWF39872.1 - 0.0098 15.5 0.1 0.34 10.4 0.1 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region FapA PF03961.13 OWF39872.1 - 0.18 10.3 4.2 0.28 9.8 4.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 OWF39872.1 - 0.27 10.0 6.4 0.37 9.6 6.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter NHL PF01436.21 OWF39872.1 - 2.1 8.5 7.7 1.1e+02 3.1 0.0 5.2 6 0 0 6 6 6 0 NHL repeat Ig_3 PF13927.6 OWF39873.1 - 4.4e-62 206.6 0.8 1.1e-12 48.3 0.2 6.7 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 OWF39873.1 - 8.2e-50 166.8 0.0 4.4e-10 39.5 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF39873.1 - 1.3e-43 147.2 2.3 1.9e-09 37.7 0.1 6.6 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 OWF39873.1 - 1.5e-30 105.3 6.7 3.4e-07 30.5 0.1 4.8 4 0 0 4 4 4 4 Fibronectin type III domain ig PF00047.25 OWF39873.1 - 8.1e-29 99.6 0.0 2.2e-07 30.9 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 OWF39873.1 - 1.1e-14 54.5 11.2 0.02 15.1 0.0 8.4 6 5 1 8 8 8 4 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF39873.1 - 2.2e-07 30.3 0.5 3.1 7.4 0.0 5.9 6 0 0 6 6 6 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF39873.1 - 0.011 15.7 1.1 8.4 6.5 0.0 5.0 6 0 0 6 6 6 0 C17orf99 Ig domain Receptor_2B4 PF11465.8 OWF39873.1 - 0.037 14.2 0.3 31 4.8 0.0 4.7 6 0 0 6 6 6 0 Natural killer cell receptor 2B4 Pur_ac_phosph_N PF16656.5 OWF39873.1 - 0.047 14.3 5.2 0.57 10.8 0.0 4.0 4 1 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain AIM24 PF01987.17 OWF39873.1 - 0.057 13.2 0.2 0.37 10.5 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial biogenesis AIM24 ROKNT PF08067.11 OWF39874.1 - 3.4 8.0 26.4 1.8 8.9 0.5 5.5 4 1 2 6 6 6 0 ROKNT (NUC014) domain DDE_Tnp_1 PF01609.21 OWF39875.1 - 0.098 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain TAN PF11640.8 OWF39876.1 - 0.063 13.4 0.3 0.11 12.6 0.1 1.5 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Trypsin PF00089.26 OWF39877.1 - 2.9e-65 220.2 0.5 2.9e-65 220.2 0.5 2.0 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 OWF39877.1 - 7e-07 30.3 0.0 1.5e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF39877.1 - 0.0018 18.6 0.1 0.0041 17.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) GSHPx PF00255.19 OWF39878.1 - 5.1e-21 74.3 0.1 7.8e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione peroxidase PSI PF01437.25 OWF39878.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Plexin repeat Sulfotransfer_1 PF00685.27 OWF39879.1 - 1.6e-13 50.8 0.5 1.2e-12 47.9 0.5 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF39879.1 - 1.3e-09 38.8 0.2 6.6e-08 33.2 0.2 2.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF39879.1 - 0.0073 16.2 7.6 0.017 15.1 7.5 1.7 1 1 0 1 1 1 1 Sulfotransferase family NAGidase PF07555.13 OWF39879.1 - 0.024 14.0 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Rotamase_2 PF13145.6 OWF39879.1 - 0.034 15.0 0.1 15 6.4 0.0 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain Ependymin PF00811.18 OWF39880.1 - 4.7e-09 36.6 0.0 7.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ependymin TLD PF07534.16 OWF39881.1 - 5.6e-13 49.3 1.5 1e-12 48.5 1.5 1.4 1 0 0 1 1 1 1 TLD MMR_HSR1 PF01926.23 OWF39881.1 - 8.3e-05 22.6 0.0 0.00021 21.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF39881.1 - 0.00012 21.9 0.5 0.06 13.1 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OWF39881.1 - 0.00062 19.7 0.1 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 OWF39881.1 - 0.00092 18.5 0.3 0.0034 16.6 0.1 1.9 2 0 0 2 2 2 1 G-protein alpha subunit AAA_29 PF13555.6 OWF39881.1 - 0.0036 17.0 0.1 0.012 15.3 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.16 OWF39881.1 - 0.0083 15.5 0.2 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 OWF39881.1 - 0.011 15.1 0.7 0.026 13.8 0.0 1.9 2 1 0 2 2 2 0 Septin PRK PF00485.18 OWF39881.1 - 0.022 14.5 0.0 0.061 13.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Gtr1_RagA PF04670.12 OWF39881.1 - 0.069 12.5 0.6 11 5.3 0.2 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF5043 PF16446.5 OWF39881.1 - 0.85 9.6 3.9 0.84 9.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5043) TLD PF07534.16 OWF39882.1 - 1.1e-14 54.8 0.8 2e-14 54.0 0.8 1.5 1 0 0 1 1 1 1 TLD MMR_HSR1 PF01926.23 OWF39882.1 - 2.2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF39882.1 - 6.2e-05 23.0 0.2 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 OWF39882.1 - 6.2e-05 22.4 0.2 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 AIG1 family ATP_bind_1 PF03029.17 OWF39882.1 - 0.0001 22.2 0.4 0.027 14.2 0.1 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein PRK PF00485.18 OWF39882.1 - 0.0048 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 OWF39882.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Septin Gtr1_RagA PF04670.12 OWF39882.1 - 0.033 13.5 0.4 4.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF39882.1 - 0.042 13.0 0.1 0.074 12.2 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 OWF39882.1 - 0.078 12.5 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region IIGP PF05049.13 OWF39882.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Fanconi_A PF03511.14 OWF39882.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein Peptidase_A17 PF05380.13 OWF39882.1 - 0.12 12.4 1.2 0.56 10.2 0.2 2.3 2 1 1 3 3 3 0 Pao retrotransposon peptidase AAA_29 PF13555.6 OWF39882.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TLD PF07534.16 OWF39883.1 - 2.3e-15 57.1 0.2 3.7e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 TLD MMR_HSR1 PF01926.23 OWF39883.1 - 7.2e-05 22.8 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF39883.1 - 0.0003 20.7 0.4 0.049 13.4 0.1 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OWF39883.1 - 0.00031 20.7 0.1 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 OWF39883.1 - 0.0044 16.4 0.1 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 AIG1 family PRK PF00485.18 OWF39883.1 - 0.0082 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 OWF39883.1 - 0.012 14.8 0.0 0.051 12.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 OWF39883.1 - 0.018 14.8 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 OWF39883.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.6 1 1 0 1 1 1 0 Septin GTP_EFTU PF00009.27 OWF39883.1 - 0.03 13.9 0.1 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF39883.1 - 0.081 12.3 0.2 9.8 5.4 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 OWF39883.1 - 0.11 12.7 0.2 0.59 10.4 0.0 2.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase COesterase PF00135.28 OWF39885.1 - 4.7e-132 441.4 0.0 5.6e-132 441.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39885.1 - 6e-09 36.1 0.7 6e-08 32.8 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF39885.1 - 0.00023 20.7 0.1 0.00039 20.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2714 PF10896.8 OWF39885.1 - 0.018 15.1 0.2 0.033 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) COesterase PF00135.28 OWF39886.1 - 6.6e-130 434.4 0.0 7.5e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39886.1 - 1.2e-08 35.1 1.8 2.4e-07 30.9 1.8 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OWF39887.1 - 4.8e-138 461.2 0.0 5.8e-138 460.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39887.1 - 0.00049 20.0 0.3 0.0016 18.3 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold TGS PF02824.21 OWF39887.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 TGS domain COesterase PF00135.28 OWF39888.1 - 3.8e-100 336.2 0.0 4.4e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39888.1 - 8.8e-09 35.5 0.6 5.2e-08 33.0 0.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF39888.1 - 0.0043 16.6 0.1 0.0059 16.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OWF39889.1 - 4.6e-15 55.5 0.0 4.8e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 OWF39890.1 - 2.3e-141 472.2 0.0 2.7e-141 472.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39890.1 - 5.1e-07 29.8 0.7 2.8e-06 27.3 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold N_methyl PF07963.12 OWF39890.1 - 1.5 8.5 3.1 3.5 7.3 3.1 1.6 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif COesterase PF00135.28 OWF39891.1 - 2.5e-136 455.6 0.0 2.9e-136 455.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF39891.1 - 3e-06 27.2 1.0 3.6e-05 23.7 1.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF39891.1 - 0.00086 18.8 0.1 0.0019 17.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family WD40 PF00400.32 OWF39892.1 - 1.5e-05 25.6 7.4 0.13 13.1 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Sec16_C PF12931.7 OWF39892.1 - 1.7e-05 24.7 1.3 0.00027 20.7 1.3 2.4 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 OWF39892.1 - 3.5e-05 23.6 0.8 9.8e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 OWF39892.1 - 0.00036 20.6 0.2 0.00075 19.6 0.2 1.5 1 0 0 1 1 1 1 Prp18 domain ANAPC4_WD40 PF12894.7 OWF39892.1 - 0.0043 17.3 0.0 0.047 14.0 0.0 2.6 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DNA_pack_N PF02500.15 OWF39892.1 - 0.066 13.0 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus DUF3005 PF11448.8 OWF39894.1 - 0.071 13.2 0.6 0.54 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) zf-C2H2 PF00096.26 OWF39895.1 - 7.6e-46 152.1 108.5 1.8e-06 28.1 1.6 13.4 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF39895.1 - 2.3e-39 130.7 103.9 0.0008 20.1 0.9 13.4 13 0 0 13 13 13 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF39895.1 - 4.1e-36 121.8 101.1 9.1e-09 35.4 1.7 14.5 16 0 0 16 16 14 9 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF39895.1 - 1.7e-22 79.1 60.3 0.0044 17.3 0.0 12.6 13 0 0 13 13 13 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF39895.1 - 1.5e-14 53.8 71.4 0.0014 18.9 0.5 12.5 13 0 0 13 13 12 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF39895.1 - 1.3e-11 44.2 77.6 0.00013 21.8 0.2 10.7 12 0 0 12 12 11 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF39895.1 - 1.9e-09 37.1 53.5 0.013 15.3 0.5 9.6 10 0 0 10 10 9 5 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OWF39895.1 - 7.4e-09 35.9 69.4 0.49 10.7 0.1 11.9 6 3 4 11 11 11 5 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 OWF39895.1 - 0.0033 17.0 0.2 0.028 14.0 0.1 9.3 9 4 3 12 12 11 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 OWF39895.1 - 0.0045 17.4 0.4 0.0045 17.4 0.4 9.9 6 3 5 11 11 10 1 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 OWF39895.1 - 0.0061 17.2 0.3 0.0061 17.2 0.3 7.7 10 1 1 11 11 7 1 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 OWF39895.1 - 0.014 15.5 42.3 2.1 8.5 2.7 9.1 10 0 0 10 10 10 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 OWF39895.1 - 0.024 14.5 41.2 0.62 9.9 0.0 9.7 8 3 4 12 12 12 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 OWF39895.1 - 0.03 14.6 61.7 0.37 11.1 7.0 8.2 5 2 3 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_SprT PF17283.2 OWF39895.1 - 0.031 14.2 39.7 0.22 11.4 2.3 8.1 8 1 0 8 8 7 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 OWF39895.1 - 0.033 14.0 0.2 0.033 14.0 0.2 13.1 12 2 0 12 12 12 0 C2H2-type zinc-finger domain GAGA PF09237.11 OWF39895.1 - 0.057 13.2 20.4 3.5 7.5 0.2 6.0 6 1 1 7 7 7 0 GAGA factor HTH_47 PF16221.5 OWF39895.1 - 0.17 11.5 0.2 5.4 6.7 0.1 2.4 2 0 0 2 2 2 0 winged helix-turn-helix HscB_4_cys PF18256.1 OWF39895.1 - 0.43 10.4 0.0 0.43 10.4 0.0 4.8 6 0 0 6 6 5 0 Co-chaperone HscB tetracysteine metal binding motif Zn-C2H2_12 PF18112.1 OWF39895.1 - 0.5 10.9 0.1 0.5 10.9 0.1 7.5 7 0 0 7 7 7 0 Autophagy receptor zinc finger-C2H2 domain Ribosomal_S15 PF00312.22 OWF39895.1 - 2.4 8.4 5.9 13 6.1 0.0 3.7 4 0 0 4 4 4 0 Ribosomal protein S15 FOP_dimer PF09398.10 OWF39896.1 - 1.1e-20 73.7 0.2 2.3e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 OWF39896.1 - 3.7e-06 25.8 0.0 5.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 LisH ABC_transp_aux PF09822.9 OWF39896.1 - 0.059 12.8 0.1 0.065 12.7 0.1 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Mito_carr PF00153.27 OWF39897.1 - 7e-54 179.7 2.5 3.7e-17 62.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein ENOD93 PF03386.14 OWF39897.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein UQ_con PF00179.26 OWF39898.1 - 3e-45 153.3 0.0 3.4e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF39898.1 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UPF0300 PF08594.10 OWF39899.1 - 0.0084 15.4 0.1 2 7.7 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0300) F420_oxidored PF03807.17 OWF39900.1 - 4.8e-16 59.1 0.0 1.1e-15 57.9 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 OWF39900.1 - 1.6e-08 34.7 5.4 1.6e-08 34.7 5.4 3.1 3 1 1 4 4 4 1 Ferric reductase like transmembrane component 2-Hacid_dh_C PF02826.19 OWF39900.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OWF39900.1 - 1.7e-05 25.0 0.0 2.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OWF39900.1 - 0.00018 21.6 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 OWF39900.1 - 0.0082 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 OWF39900.1 - 0.031 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF4872 PF16169.5 OWF39902.1 - 0.16 11.7 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) RGS PF00615.19 OWF39903.1 - 2.8e-34 117.9 0.7 3.6e-34 117.6 0.7 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain PMG PF05287.12 OWF39904.1 - 0.0011 19.0 16.1 0.019 15.0 13.3 2.4 1 1 1 2 2 2 2 PMG protein EB PF01683.18 OWF39904.1 - 4.5 7.6 21.5 1.4e+02 2.8 6.3 4.7 1 1 1 2 2 2 0 EB module Keratin_B2 PF01500.17 OWF39904.1 - 6 6.8 16.4 40 4.2 16.4 1.9 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Prolamin_like PF05617.11 OWF39904.1 - 6.5 7.0 13.8 5.2 7.3 1.0 3.1 1 1 1 2 2 2 0 Prolamin-like DKCLD PF08068.12 OWF39905.1 - 0.0001 22.3 0.3 0.0078 16.3 0.1 2.5 2 0 0 2 2 2 2 DKCLD (NUC011) domain Neuregulin PF02158.15 OWF39905.1 - 0.054 12.9 0.9 7.1 5.9 0.1 2.1 2 0 0 2 2 2 0 Neuregulin intracellular region DUF5323 PF17257.2 OWF39906.1 - 1.3e-11 44.1 51.2 1.2 9.1 0.3 10.4 1 1 14 15 15 15 15 Family of unknown function (DUF5323) YflT PF11181.8 OWF39906.1 - 1e-05 26.0 2.1 10 6.7 0.0 4.7 2 1 2 4 4 4 2 Heat induced stress protein YflT T2SSE_N PF05157.15 OWF39906.1 - 0.064 13.5 5.8 51 4.2 0.1 4.6 1 1 3 5 5 5 0 Type II secretion system (T2SS), protein E, N-terminal domain DUF4249 PF14054.6 OWF39906.1 - 1.9 8.1 42.6 3.6e+02 0.6 15.9 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4249) Cytochrome_P460 PF16694.5 OWF39906.1 - 3.1 8.2 17.2 22 5.4 6.7 3.4 1 1 2 3 3 3 0 Cytochrome P460 BCD PF15461.6 OWF39906.1 - 3.9 6.9 6.0 1.2 8.5 0.3 2.6 1 1 2 3 3 3 0 Beta-carotene 15,15'-dioxygenase GH97_C PF14509.6 OWF39906.1 - 3.9 7.8 5.3 81 3.5 1.4 3.2 1 1 2 3 3 3 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation IMP2_C PF18591.1 OWF39906.1 - 4.7 7.1 16.4 59 3.6 0.1 5.7 1 1 6 7 7 7 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Defensin_1 PF00323.19 OWF39908.1 - 2.8e-05 24.6 10.1 3.8 8.2 0.1 4.9 2 2 3 5 5 5 3 Mammalian defensin Imm72 PF15584.6 OWF39908.1 - 0.0013 18.8 3.3 1.4 9.1 0.1 3.5 1 1 3 4 4 4 2 Immunity protein 72 Dioxygenase_C PF00775.21 OWF39908.1 - 0.16 11.4 1.8 5.9 6.3 0.3 2.7 1 1 1 2 2 2 0 Dioxygenase IL4Ra_N PF09238.10 OWF39908.1 - 0.27 11.6 8.7 1.7 9.1 3.7 2.3 1 1 1 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal Cmc1 PF08583.10 OWF39908.1 - 0.5 10.4 11.3 6 7.0 1.3 3.3 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Gag_p15 PF08723.10 OWF39908.1 - 1.1 9.4 2.7 50 4.1 0.1 3.2 1 1 2 3 3 3 0 Gag protein p15 Mersacidin PF16934.5 OWF39908.1 - 2 8.2 7.9 10 6.0 0.1 3.3 1 1 3 4 4 4 0 Two-component Enterococcus faecalis cytolysin (EFC) Gamma-thionin PF00304.20 OWF39908.1 - 3.2 8.1 18.5 9.3 6.6 2.5 4.0 2 2 1 3 3 3 0 Gamma-thionin family EcpB_C PF18649.1 OWF39908.1 - 4.8 7.2 17.3 7.8 6.5 1.1 3.6 1 1 3 4 4 4 0 EcpB C-terminal domain GH97_C PF14509.6 OWF39909.1 - 4.6e-46 155.0 99.6 5.5 7.3 0.2 31.4 1 1 54 56 56 56 56 Glycosyl-hydrolase 97 C-terminal, oligomerisation Mucin-like PF16058.5 OWF39910.1 - 6.7e-22 77.5 0.0 2.2e-06 27.6 0.0 4.3 1 1 4 5 5 5 5 Mucin-like Autophagy_N PF03986.13 OWF39910.1 - 0.11 12.4 0.5 2.2e+02 1.7 0.0 4.6 2 1 3 6 6 6 0 Autophagocytosis associated protein (Atg3), N-terminal domain Antimicrobial24 PF16049.5 OWF39911.1 - 2e-05 24.5 10.7 2e+02 2.0 0.0 9.5 10 0 0 10 10 10 0 Frog antimicrobial peptide Picorna_P3A PF06363.11 OWF39911.1 - 0.0001 22.1 2.4 0.16 11.9 0.3 3.3 1 1 1 2 2 2 2 Picornaviridae P3A protein Cellulose_synt PF03552.14 OWF39911.1 - 0.017 13.7 0.0 0.082 11.4 0.0 1.9 1 1 0 1 1 1 0 Cellulose synthase DUF787 PF05619.11 OWF39911.1 - 3.5 6.7 5.7 11 5.0 0.3 2.8 1 1 2 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF787) Sulfotransfer_1 PF00685.27 OWF39912.1 - 1.8e-10 40.7 1.7 3.5e-10 39.8 1.7 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF39912.1 - 0.00034 21.1 0.3 0.017 15.5 0.3 3.0 1 1 0 1 1 1 1 Sulfotransferase family GST_N_4 PF17172.4 OWF39913.1 - 1.9e-24 86.3 0.0 2.6e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF39913.1 - 1.3e-17 63.3 0.0 2e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF39913.1 - 6.6e-08 32.9 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 OWF39913.1 - 0.00079 19.8 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF39913.1 - 0.0019 18.2 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF39913.1 - 0.007 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF39913.1 - 0.0078 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF39913.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain fn3 PF00041.21 OWF39915.1 - 3.9e-06 27.1 4.7 0.00016 22.0 1.6 3.4 2 1 0 2 2 2 2 Fibronectin type III domain Swi5 PF07061.11 OWF39917.1 - 3.7e-20 71.8 0.8 5.4e-20 71.3 0.8 1.3 1 0 0 1 1 1 1 Swi5 NPV_P10 PF05531.12 OWF39917.1 - 0.001 19.5 0.5 0.0014 19.1 0.5 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 OWF39917.1 - 0.0052 16.6 1.8 0.0072 16.1 1.8 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Cry1Ac_D5 PF17997.1 OWF39917.1 - 0.0087 15.9 0.3 0.016 15.1 0.0 1.5 1 1 1 2 2 2 1 Insecticidal delta-endotoxin CryIA(c) domain 5 Wbp11 PF09429.10 OWF39917.1 - 0.027 14.9 1.2 0.097 13.1 1.2 1.8 1 1 0 1 1 1 0 WW domain binding protein 11 FH2 PF02181.23 OWF39917.1 - 0.033 13.3 0.8 0.04 13.1 0.8 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF2781 PF10914.8 OWF39918.1 - 8e-14 52.3 23.4 2.4e-13 50.7 8.1 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF2781) DUF5317 PF17248.2 OWF39918.1 - 0.054 13.5 5.8 0.09 12.8 0.7 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5317) OAD_gamma PF04277.13 OWF39918.1 - 2.4 8.8 8.2 12 6.6 2.8 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain bZIP_1 PF00170.21 OWF39920.1 - 1.7e-10 40.8 17.8 1.7e-10 40.8 17.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OWF39920.1 - 9.5e-06 25.6 16.6 1.8e-05 24.7 15.2 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF39920.1 - 0.0011 19.4 11.9 0.0011 19.4 11.9 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor MCU PF04678.13 OWF39920.1 - 0.049 13.7 0.5 0.12 12.4 0.5 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter V_ATPase_I PF01496.19 OWF39920.1 - 0.13 10.2 5.1 0.22 9.4 5.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 OWF39920.1 - 0.24 11.2 7.0 0.55 10.0 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 OWF39920.1 - 0.27 11.0 8.6 0.58 10.0 8.1 1.8 1 1 0 1 1 1 0 Septum formation initiator YabA PF06156.13 OWF39920.1 - 0.27 11.9 10.8 0.058 14.0 4.7 2.7 2 1 1 3 3 3 0 Initiation control protein YabA UPF0449 PF15136.6 OWF39920.1 - 0.27 11.7 6.0 0.93 10.0 6.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF4337 PF14235.6 OWF39920.1 - 0.73 9.9 2.9 1.5 8.9 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NYD-SP28_assoc PF14775.6 OWF39920.1 - 0.99 9.6 7.5 2.6 8.2 7.5 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain UPF0242 PF06785.11 OWF39920.1 - 1.8 8.6 11.1 0.21 11.7 5.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus IATP PF04568.12 OWF39920.1 - 3.5 8.1 6.5 2.6 8.6 3.7 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP TSC22 PF01166.18 OWF39920.1 - 4.3 7.7 9.8 9.2 6.7 5.8 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family ssDNA_DBD PF18333.1 OWF39920.1 - 4.3 7.5 9.1 1.2 9.3 5.3 2.0 2 0 0 2 2 2 0 Non-canonical single-stranded DNA-binding domain DUF2992 PF11208.8 OWF39920.1 - 7.9 6.7 15.1 0.36 11.1 7.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) SlyX PF04102.12 OWF39920.1 - 8 7.2 10.3 1.9 9.2 5.9 2.3 2 0 0 2 2 1 0 SlyX Peptidase_M16_C PF05193.21 OWF39921.1 - 6.2e-16 58.9 0.1 4.3e-15 56.2 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 OWF39921.1 - 1.6e-09 37.3 0.2 4.9e-09 35.7 0.1 1.9 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16 PF00675.20 OWF39921.1 - 9.3e-09 35.4 0.0 1.1e-06 28.8 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Spp-24 PF07448.11 OWF39921.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Prefoldin_2 PF01920.20 OWF39921.1 - 0.76 9.8 12.5 0.054 13.5 1.4 3.3 3 0 0 3 3 3 0 Prefoldin subunit Collagen PF01391.18 OWF39922.1 - 6.4e-162 525.5 609.8 8.7e-09 35.0 23.9 21.2 2 1 14 16 16 16 13 Collagen triple helix repeat (20 copies) COLFI PF01410.18 OWF39922.1 - 2.4e-64 216.8 0.3 3.4e-64 216.4 0.3 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Adap_comp_sub PF00928.21 OWF39923.1 - 3.8e-74 249.4 0.0 4.6e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OWF39923.1 - 1.4e-07 31.5 1.2 2.4e-07 30.8 1.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ PF00595.24 OWF39924.1 - 2.3e-39 133.6 3.3 3.2e-13 49.8 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 OWF39924.1 - 8.1e-28 96.0 1.1 4.5e-08 32.8 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OWF39924.1 - 1.5e-14 54.1 0.3 0.0023 18.2 0.0 3.7 3 0 0 3 3 3 3 PDZ domain CCM2_C PF16545.5 OWF39924.1 - 3.5e-05 24.3 0.1 0.052 14.1 0.0 2.4 2 0 0 2 2 2 2 Cerebral cavernous malformation protein, harmonin-homology DSHCT PF08148.12 OWF39926.1 - 1.4e-50 171.2 0.4 3.3e-50 170.0 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OWF39926.1 - 4e-39 135.2 0.1 8.9e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Ski2_N PF17911.1 OWF39926.1 - 6.2e-32 110.2 0.0 1.5e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 OWF39926.1 - 3.8e-20 72.4 0.2 1.1e-19 70.9 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF39926.1 - 8e-08 32.6 0.0 2.6e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CholecysA-Rec_N PF09193.10 OWF39926.1 - 0.03 14.3 0.1 0.69 10.0 0.0 2.7 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal DUF3516 PF12029.8 OWF39926.1 - 0.058 12.5 0.5 0.13 11.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) ATPase_2 PF01637.18 OWF39926.1 - 0.11 12.3 1.4 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea EF-hand_1 PF00036.32 OWF39927.1 - 8.8e-13 46.8 2.1 0.00037 19.9 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 OWF39927.1 - 2.6e-12 45.6 1.5 6.1e-05 22.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OWF39927.1 - 2.9e-09 36.1 6.9 0.0058 16.5 0.1 3.5 2 1 1 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 OWF39927.1 - 6.9e-09 36.0 4.8 0.035 14.5 0.3 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 OWF39927.1 - 1.1e-07 31.5 3.2 0.00071 19.4 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF39927.1 - 0.095 13.0 0.7 7.1 7.0 0.0 2.8 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region 7tm_1 PF00001.21 OWF39928.1 - 3.4e-27 95.4 7.7 7.6e-27 94.3 7.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF39928.1 - 0.00036 20.2 8.8 0.00036 20.2 8.8 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.9 OWF39928.1 - 0.036 12.9 3.4 5.3 5.7 0.0 3.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Cauli_DNA-bind PF03310.13 OWF39928.1 - 0.089 12.9 1.0 0.2 11.7 1.0 1.6 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Tmemb_9 PF05434.11 OWF39928.1 - 3.9 7.3 13.2 0.56 10.1 1.0 3.1 3 0 0 3 3 3 0 TMEM9 Git3 PF11710.8 OWF39928.1 - 7.9 6.2 15.7 0.57 9.9 9.6 2.1 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 PAP2 PF01569.21 OWF39929.1 - 1.7e-15 57.0 7.5 6.9e-15 55.0 7.5 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 OWF39929.1 - 0.011 15.9 0.8 0.14 12.3 0.0 2.2 1 1 1 2 2 2 0 Divergent PAP2 family Polysacc_synt_C PF14667.6 OWF39929.1 - 0.23 11.5 7.5 0.4 10.7 7.4 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain FtsX PF02687.21 OWF39929.1 - 0.41 11.1 0.1 0.41 11.1 0.1 2.2 2 0 0 2 2 2 0 FtsX-like permease family TGT PF01702.18 OWF39930.1 - 1.3e-150 501.5 0.0 1.5e-150 501.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ank_2 PF12796.7 OWF39931.1 - 1e-10 42.1 0.0 0.00021 21.8 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF39931.1 - 2e-09 37.8 0.1 0.01 16.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF39931.1 - 3.3e-09 36.8 0.1 0.11 12.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF39931.1 - 3.2e-07 30.1 1.7 0.056 14.0 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ion_trans PF00520.31 OWF39931.1 - 1.8e-05 24.1 19.5 2.8e-05 23.5 19.5 1.4 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 OWF39931.1 - 0.0031 17.9 0.8 2.7 8.6 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat DUF1218 PF06749.12 OWF39931.1 - 0.18 12.3 9.3 1.2 9.7 1.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Ank_2 PF12796.7 OWF39932.1 - 2.4e-07 31.3 0.1 0.00034 21.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF39932.1 - 3.9e-05 23.7 2.4 0.65 10.7 0.0 5.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OWF39932.1 - 0.00054 20.5 0.2 0.049 14.2 0.1 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF39932.1 - 0.00078 19.7 0.2 4.3 7.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF39932.1 - 0.0009 19.6 0.9 0.12 12.9 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OWF39933.1 - 9.1e-11 42.2 0.3 5.1e-06 27.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF39933.1 - 9.5e-10 37.9 0.8 2.6 8.9 0.1 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF39933.1 - 1.5e-08 34.7 0.0 0.084 13.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF39933.1 - 1.1e-07 32.2 1.1 0.042 14.5 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 OWF39933.1 - 1.2e-05 24.6 29.0 2.8e-05 23.4 28.7 1.7 1 1 0 1 1 1 1 Ion transport protein Ank PF00023.30 OWF39933.1 - 4.4e-05 23.7 0.0 0.64 10.6 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat DUF3487 PF11990.8 OWF39933.1 - 0.098 12.5 2.7 0.15 11.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF5134 PF17197.4 OWF39934.1 - 0.11 12.4 4.0 8.2 6.3 4.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Ferlin_C PF16165.5 OWF39934.1 - 1.6 8.7 5.3 0.46 10.4 0.9 2.5 2 0 0 2 2 2 0 Ferlin C-terminus DUF202 PF02656.15 OWF39934.1 - 1.9 9.0 12.0 23 5.5 4.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Comm PF15957.5 OWF39934.1 - 9.5 6.6 6.3 47 4.4 0.2 2.7 2 0 0 2 2 2 0 Commissureless Ank_4 PF13637.6 OWF39935.1 - 3.4e-09 37.0 0.0 0.0065 17.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF39935.1 - 1.1e-08 35.5 0.3 0.00012 22.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF39935.1 - 4.8e-08 32.6 0.1 2.8 8.8 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF39935.1 - 2.3e-06 27.7 0.0 0.37 11.2 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF39935.1 - 0.001 19.4 0.2 4.8 7.8 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat SRCR PF00530.18 OWF39936.1 - 6.3e-16 58.7 0.1 1.8e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain 7tm_2 PF00002.24 OWF39937.1 - 5.6e-18 65.1 25.2 1.2e-17 64.0 25.2 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 OWF39937.1 - 0.0014 19.0 22.6 0.034 14.5 9.5 3.5 2 0 0 2 2 2 2 Somatomedin B domain Fibrinogen_C PF00147.18 OWF39938.1 - 1.2e-24 87.4 1.0 4.9e-24 85.4 1.0 1.8 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF39939.1 - 1e-18 68.0 1.6 1.1e-18 67.8 1.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PilS PF08805.11 OWF39939.1 - 0.1 12.4 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 PilS N terminal Fibrinogen_C PF00147.18 OWF39940.1 - 7e-45 153.5 0.9 8.6e-45 153.2 0.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SopD PF11047.8 OWF39940.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Salmonella outer protein D 7tm_2 PF00002.24 OWF39941.1 - 1.4e-11 44.1 26.3 2.5e-11 43.3 26.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) CECR6_TMEM121 PF14997.6 OWF39942.1 - 5.1e-42 143.9 2.7 5.1e-42 143.9 2.7 1.4 2 0 0 2 2 2 1 CECR6/TMEM121 family Cyt_c_ox_IV PF12270.8 OWF39942.1 - 2.3e-05 24.6 0.5 0.00024 21.2 0.3 2.2 1 1 1 2 2 2 1 Cytochrome c oxidase subunit IV DUF2339 PF10101.9 OWF39942.1 - 0.00063 18.5 0.4 0.00081 18.1 0.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) FeoB_associated PF12669.7 OWF39942.1 - 0.0021 18.4 3.3 0.14 12.6 0.0 4.0 4 0 0 4 4 4 1 FeoB-associated Cys-rich membrane protein DUF928 PF06051.12 OWF39943.1 - 0.00033 20.6 4.5 14 5.5 0.0 5.4 2 2 4 6 6 6 2 Domain of Unknown Function (DUF928) CHORD PF04968.12 OWF39943.1 - 0.0033 18.1 5.3 99 3.8 0.1 6.4 3 2 3 7 7 7 0 CHORD MerB PF03243.15 OWF39943.1 - 0.038 14.1 7.4 9.5 6.4 0.1 4.0 2 2 1 4 4 4 0 Alkylmercury lyase YueH PF14166.6 OWF39943.1 - 0.039 13.8 0.5 76 3.3 0.0 4.6 4 2 2 6 6 6 0 YueH-like protein Levi_coat PF01819.17 OWF39943.1 - 0.14 12.2 2.2 10 6.2 0.1 3.6 1 1 3 4 4 4 0 Levivirus coat protein Bromodomain PF00439.25 OWF39943.1 - 0.57 10.3 14.6 25 5.0 0.1 5.5 2 2 4 6 6 6 0 Bromodomain ApoB100_C PF12491.8 OWF39943.1 - 1.4 8.9 9.6 53 3.9 0.1 4.8 5 0 0 5 5 5 0 Apolipoprotein B100 C terminal DUF5465 PF17553.2 OWF39943.1 - 6.6 7.6 6.8 78 4.2 0.1 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5465) Ribosomal_S7 PF00177.21 OWF39944.1 - 1.5e-37 128.5 0.3 1.9e-37 128.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ocnus PF05005.15 OWF39945.1 - 9.5e-22 77.2 0.2 1.1e-21 77.0 0.2 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) HTH_CodY PF08222.11 OWF39946.1 - 2.4e-06 27.0 0.0 5.3 6.7 0.0 5.5 1 1 6 8 8 8 2 CodY helix-turn-helix domain IKKbetaNEMObind PF12179.8 OWF39946.1 - 2.8e-05 24.0 51.8 22 5.2 0.3 13.4 1 1 9 11 11 11 9 I-kappa-kinase-beta NEMO binding domain Bromo_TP PF07524.13 OWF39946.1 - 0.00021 21.2 15.4 9.3 6.3 0.3 5.5 1 1 8 9 9 9 9 Bromodomain associated DUF1700 PF08006.11 OWF39946.1 - 0.86 9.1 37.4 6.3 6.3 9.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1700) C4bp_oligo PF18453.1 OWF39947.1 - 0.019 15.1 0.2 20 5.5 0.0 3.6 1 1 3 4 4 4 0 Oligomerization domain of C4b-binding protein alpha TAD2 PF18521.1 OWF39947.1 - 0.097 12.7 13.9 34 4.7 2.0 4.9 1 1 4 5 5 5 0 Transactivation domain 2 SSF PF00474.17 OWF39948.1 - 7.4e-45 153.5 28.7 7.4e-45 153.5 28.7 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family SSF PF00474.17 OWF39949.1 - 1.9e-41 142.3 25.4 1.9e-41 142.3 25.4 1.7 1 1 1 2 2 2 1 Sodium:solute symporter family NdhL PF10716.9 OWF39949.1 - 0.02 14.8 1.2 0.02 14.8 1.2 2.4 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit Prenyltrans PF00432.21 OWF39949.1 - 0.43 10.4 2.9 5.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Carb_bind PF10645.9 OWF39950.1 - 0.036 14.3 6.9 15 5.9 0.4 4.4 3 1 1 4 4 4 0 Carbohydrate binding Ldl_recept_a PF00057.18 OWF39950.1 - 0.098 12.9 20.3 13 6.1 0.1 6.2 1 1 10 11 11 11 0 Low-density lipoprotein receptor domain class A Peptidase_S8_N PF16361.5 OWF39950.1 - 0.17 12.4 0.7 0.22 12.0 0.7 1.1 1 0 0 1 1 1 0 N-terminal of Subtilase family Homeodomain PF00046.29 OWF39951.1 - 9.6e-23 79.8 6.3 2.3e-22 78.6 6.3 1.7 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 OWF39951.1 - 2.4e-05 24.0 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF39951.1 - 0.00063 19.6 0.1 0.00063 19.6 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain FAM176 PF14851.6 OWF39951.1 - 0.86 9.3 4.0 1.3 8.7 4.0 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 OWF39951.1 - 1.5 7.1 5.4 2.1 6.5 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_10 PF00852.19 OWF39953.1 - 3.2e-49 167.0 0.9 5.9e-49 166.2 0.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF39953.1 - 3.6e-18 66.0 1.4 9.6e-18 64.7 1.4 1.8 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal SURF6 PF04935.12 OWF39954.1 - 2.9e-35 121.9 53.4 2.9e-35 121.9 53.4 2.1 1 1 1 2 2 2 1 Surfeit locus protein 6 VIR_N PF15912.5 OWF39954.1 - 9.1 5.8 20.1 7.7 6.0 6.9 2.4 2 0 0 2 2 2 0 Virilizer, N-terminal DUF4071 PF13281.6 OWF39955.1 - 0.19 10.7 4.0 0.093 11.8 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4071) DUF349 PF03993.12 OWF39955.1 - 8.2 6.8 13.1 43 4.5 12.7 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) Methyltransf_11 PF08241.12 OWF39956.1 - 8.4e-16 58.4 0.1 3.2e-14 53.3 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF39956.1 - 4.7e-13 49.7 0.2 6.9e-12 45.9 0.1 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF39956.1 - 2.9e-11 43.4 5.3 2.4e-09 37.1 1.7 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OWF39956.1 - 3.3e-07 30.9 0.1 1.5e-05 25.7 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF39956.1 - 0.00098 19.0 0.0 0.048 13.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OWF39956.1 - 0.0036 17.3 0.6 0.014 15.4 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF39956.1 - 0.005 16.2 2.1 0.0068 15.8 0.4 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Rieske PF00355.26 OWF39957.1 - 2.1e-17 62.8 0.0 3.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OWF39957.1 - 0.00055 19.8 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Methyltransf_11 PF08241.12 OWF39958.1 - 0.00011 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF39958.1 - 0.0003 21.4 0.0 0.0006 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF39958.1 - 0.13 12.1 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TPR_19 PF14559.6 OWF39958.1 - 0.15 12.6 0.0 0.53 10.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3432 PF11914.8 OWF39959.1 - 1.1e-32 112.2 281.2 0.24 11.6 17.5 18.5 1 1 18 19 19 19 17 Domain of unknown function (DUF3432) DUF3432 PF11914.8 OWF39960.1 - 3.8e-08 33.5 93.4 0.037 14.3 11.6 7.3 1 1 6 7 7 7 6 Domain of unknown function (DUF3432) DUF3928 PF13065.6 OWF39960.1 - 0.49 11.2 38.8 20 6.0 0.6 9.5 1 1 7 9 9 9 0 Protein of unknown function (DUF3928) Glyco_hydro_59 PF02057.15 OWF39962.1 - 0.0079 15.5 0.2 0.0085 15.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 PSP94 PF05825.11 OWF39963.1 - 0.027 15.0 4.0 0.055 14.0 4.0 1.5 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) DUF3696 PF12476.8 OWF39963.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) PSP94 PF05825.11 OWF39964.1 - 0.1 13.2 2.3 0.14 12.7 2.3 1.2 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) CRIM PF16978.5 OWF39965.1 - 1e-31 109.9 0.0 2.3e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OWF39965.1 - 1.9e-30 105.3 0.4 5.4e-30 103.9 0.3 1.8 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SIN1 PF05422.12 OWF39965.1 - 4.1e-24 85.8 10.4 1.2e-20 74.5 6.7 3.9 2 2 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) Sulfatase PF00884.23 OWF39966.1 - 4.7e-70 236.4 0.1 6.5e-70 236.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OWF39966.1 - 0.0022 18.7 0.0 0.0072 17.1 0.0 1.8 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 OWF39966.1 - 0.0031 17.4 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF1501 PF07394.12 OWF39966.1 - 0.018 14.1 0.9 0.027 13.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SF3a60_bindingd PF12108.8 OWF39967.1 - 1.4e-07 31.3 15.7 13 5.8 0.0 7.9 5 1 2 7 7 7 3 Splicing factor SF3a60 binding domain U62_UL91 PF17442.2 OWF39967.1 - 6.9e-07 29.2 7.0 0.98 9.4 0.2 4.5 1 1 5 6 6 6 6 Functional domain of U62 and UL91 proteins DHC_N2 PF08393.13 OWF39967.1 - 0.00039 19.7 1.0 0.00054 19.2 1.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 DUF5530 PF17670.1 OWF39967.1 - 0.009 15.8 4.8 8.1 6.2 0.1 3.5 1 1 3 4 4 4 4 Family of unknown function (DUF5530) TRC8_N PF13705.6 OWF39967.1 - 0.0099 14.8 0.4 1.6 7.6 0.1 2.4 1 1 1 2 2 2 2 TRC8 N-terminal domain T3SS_ATPase_C PF18269.1 OWF39967.1 - 0.011 15.6 3.2 1.3e+02 2.5 0.0 4.8 4 1 0 5 5 5 0 T3SS EscN ATPase C-terminal domain Y1_Tnp PF01797.16 OWF39967.1 - 0.048 13.8 14.6 5.7 7.1 0.3 4.9 1 1 4 5 5 5 0 Transposase IS200 like DUF2730 PF10805.8 OWF39967.1 - 0.071 13.2 1.1 15 5.7 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) PAT1 PF09770.9 OWF39967.1 - 0.11 10.8 6.5 3.5 5.8 0.3 3.1 1 1 2 3 3 3 0 Topoisomerase II-associated protein PAT1 Arena_nucleocap PF00843.17 OWF39967.1 - 0.14 11.0 5.0 3.1 6.6 1.3 2.4 1 1 2 3 3 3 0 Arenavirus nucleocapsid N-terminal domain Sulfatase PF00884.23 OWF39968.1 - 6.5e-72 242.5 0.6 8.7e-72 242.1 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OWF39968.1 - 0.0019 18.9 0.0 0.0078 16.9 0.0 2.0 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 OWF39968.1 - 0.048 12.7 1.2 0.08 12.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Peptidase_C14 PF00656.22 OWF39969.1 - 2.6e-22 80.0 0.1 5.6e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Caspase domain Fibrinogen_C PF00147.18 OWF39970.1 - 7.2e-28 97.9 0.3 9.9e-28 97.4 0.3 1.2 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF39970.1 - 0.0011 18.9 0.4 0.002 18.1 0.4 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF39970.1 - 0.07 13.0 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 PAN domain PUCC PF03209.15 OWF39971.1 - 0.039 12.9 1.1 0.042 12.8 1.1 1.1 1 0 0 1 1 1 0 PUCC protein MFS_1 PF07690.16 OWF39971.1 - 0.37 9.7 6.4 0.47 9.3 6.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily ABC2_membrane PF01061.24 OWF39975.1 - 9.2e-37 126.5 21.8 9.2e-37 126.5 21.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OWF39975.1 - 2.3e-24 86.4 0.0 3.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF39975.1 - 8.1e-05 22.6 0.0 0.042 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF39975.1 - 0.00026 20.5 0.0 0.0026 17.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OWF39975.1 - 0.001 19.0 0.1 0.0023 17.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OWF39975.1 - 0.0081 15.9 0.2 0.025 14.3 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OWF39975.1 - 0.01 15.9 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 OWF39975.1 - 0.015 15.4 0.3 0.028 14.5 0.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 OWF39975.1 - 0.05 14.0 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 OWF39975.1 - 0.059 12.5 19.5 0.14 11.3 19.2 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_25 PF13481.6 OWF39975.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 OWF39975.1 - 0.12 11.6 9.8 0.019 14.3 4.6 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_22 PF13401.6 OWF39975.1 - 0.15 12.3 0.1 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OWF39975.1 - 0.17 11.8 0.2 3.2 7.6 0.1 2.6 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 OWF39975.1 - 0.22 11.7 0.0 0.5 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OWF39975.1 - 0.4 11.2 1.1 0.87 10.1 0.3 1.8 2 0 0 2 2 2 0 AAA domain EphA2_TM PF14575.6 OWF39976.1 - 0.0013 19.6 0.0 0.0036 18.1 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 OWF39976.1 - 0.0087 15.7 0.2 0.019 14.6 0.1 1.5 2 0 0 2 2 2 1 FAM176 family ETRAMP PF09716.10 OWF39976.1 - 0.024 14.7 0.5 0.024 14.7 0.5 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Cadherin_C_2 PF16492.5 OWF39976.1 - 0.039 14.7 0.1 0.12 13.2 0.0 1.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal FAM163 PF15069.6 OWF39976.1 - 0.04 14.4 2.3 0.04 14.4 2.3 2.1 2 0 0 2 2 2 0 FAM163 family Syndecan PF01034.20 OWF39976.1 - 0.073 13.0 1.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Syndecan domain TssO PF17561.2 OWF39976.1 - 0.098 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO TRP PF06011.12 OWF39976.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Mucin PF01456.17 OWF39976.1 - 0.16 11.9 22.1 0.2 11.6 1.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Synaptobrevin PF00957.21 OWF39976.1 - 0.6 9.9 4.1 1.1 9.1 4.1 1.5 1 0 0 1 1 1 0 Synaptobrevin LYRIC PF15686.5 OWF39976.1 - 0.79 9.2 6.9 0.17 11.4 0.3 2.0 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family LRR_8 PF13855.6 OWF39977.1 - 1.8e-14 53.2 2.0 1.9e-05 24.3 0.1 3.5 1 1 4 5 5 5 4 Leucine rich repeat LRR_5 PF13306.6 OWF39977.1 - 6e-11 42.4 2.3 1.2e-10 41.5 2.3 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF39977.1 - 0.021 15.2 0.9 9.7 6.8 0.0 3.6 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Reeler PF02014.16 OWF39978.1 - 9.6e-19 68.4 0.8 1.7e-18 67.6 0.0 1.8 2 0 0 2 2 2 1 Reeler domain Citrus_P18 PF05520.11 OWF39978.1 - 0.077 12.7 0.7 0.11 12.3 0.7 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Herpes_UL16 PF03044.14 OWF39978.1 - 0.086 12.1 2.0 3 7.0 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL16/UL94 family 7tm_2 PF00002.24 OWF39979.1 - 4.9e-74 248.7 14.0 6.9e-74 248.2 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF39979.1 - 2e-17 63.2 6.2 2e-17 63.2 6.2 2.4 2 0 0 2 2 2 1 Hormone receptor domain DUF1461 PF07314.11 OWF39979.1 - 1.7 8.5 10.9 0.25 11.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) Sugar_tr PF00083.24 OWF39981.1 - 3e-32 112.1 19.2 4.9e-32 111.4 19.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF39981.1 - 1.5e-26 93.2 40.0 5.2e-24 84.8 23.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Mab-21 PF03281.14 OWF39982.1 - 1.7e-22 80.1 0.1 3.1e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Mab-21 protein TPR_8 PF13181.6 OWF39982.1 - 0.0085 16.2 0.2 1.6 9.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF39982.1 - 0.02 15.0 0.0 0.38 11.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF39982.1 - 0.031 15.1 0.0 6.8 7.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 OWF39982.1 - 0.08 12.1 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4192 PF13830.6 OWF39982.1 - 0.088 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) PLAC PF08686.11 OWF39983.1 - 0.2 12.4 6.8 0.35 11.7 6.8 1.6 1 1 0 1 1 1 0 PLAC (protease and lacunin) domain Myb_DNA-bind_5 PF13873.6 OWF39984.1 - 1.2e-15 57.3 5.1 3e-15 56.1 5.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OWF39984.1 - 1.6 9.8 7.0 0.18 12.8 1.8 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain cNMP_binding PF00027.29 OWF39986.1 - 1.9e-13 50.3 0.0 1e-11 44.7 0.0 3.0 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain Fibrinogen_C PF00147.18 OWF39987.1 - 2.4e-20 73.3 0.2 2.6e-20 73.2 0.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF39988.1 - 3.2e-40 138.3 1.2 5e-40 137.7 1.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fox-1_C PF12414.8 OWF39989.1 - 0.01 16.2 0.3 0.016 15.6 0.3 1.2 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal SAM_DrpA PF18255.1 OWF39990.1 - 0.00039 20.6 0.1 15 5.9 0.0 4.1 1 1 3 4 4 4 2 DNA processing protein A sterile alpha motif domain zf-ribbon_3 PF13248.6 OWF39990.1 - 0.018 14.5 0.1 62 3.2 0.0 5.0 6 0 0 6 6 6 0 zinc-ribbon domain Glutaredoxin2_C PF04399.13 OWF39990.1 - 0.024 14.5 0.0 55 3.6 0.0 3.2 1 1 2 4 4 4 0 Glutaredoxin 2, C terminal domain BAMBI PF06211.12 OWF39990.1 - 0.039 14.2 1.5 1 9.6 0.1 2.5 1 1 1 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain PriA_CRR PF18319.1 OWF39990.1 - 0.34 11.0 17.5 17 5.5 0.1 6.5 7 0 0 7 7 7 0 PriA DNA helicase Cys-rich region (CRR) domain RRM_1 PF00076.22 OWF39991.1 - 2.3e-32 110.6 0.0 2.3e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OWF39991.1 - 0.014 15.6 0.8 0.065 13.5 0.5 2.2 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Katanin_con80 PF13925.6 OWF39991.1 - 0.081 13.0 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 con80 domain of Katanin NAD_binding_1 PF00175.21 OWF39992.1 - 1.5e-14 54.5 0.0 4e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OWF39992.1 - 1.1e-05 25.6 0.2 0.0049 17.0 0.1 2.8 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 OWF39992.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Chibby PF14645.6 OWF39992.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Chibby family MMADHC PF10229.9 OWF39993.1 - 1.5e-74 251.2 0.0 1.8e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein dsrm PF00035.26 OWF39994.1 - 4.4e-37 126.6 1.8 2.4e-16 60.2 0.0 3.6 3 0 0 3 3 3 3 Double-stranded RNA binding motif Staufen_C PF16482.5 OWF39994.1 - 5.8e-14 52.2 1.0 7.5e-13 48.6 0.5 2.4 2 0 0 2 2 2 1 Staufen C-terminal domain DND1_DSRM PF14709.7 OWF39994.1 - 1.6e-09 37.9 6.3 0.0034 17.6 0.2 4.7 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 LRR_5 PF13306.6 OWF39996.1 - 3.9e-26 91.5 32.3 7.3e-12 45.4 0.9 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OWF39996.1 - 1.3e-11 44.0 1.2 0.00012 21.8 0.0 3.6 1 1 2 3 3 3 3 Leucine rich repeat Peptidase_C2 PF00648.21 OWF39997.1 - 7.4e-44 150.0 0.1 2.1e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.18 OWF39997.1 - 4.6e-19 68.2 9.0 5.3e-10 39.2 1.4 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 OWF39997.1 - 2.1e-13 50.7 0.0 8e-09 35.9 0.0 3.8 3 0 0 3 3 3 2 Calpain large subunit, domain III SBBP PF06739.11 OWF39997.1 - 0.15 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Beta-propeller repeat AAA_16 PF13191.6 OWF39999.1 - 3.4e-09 37.3 0.0 4.2e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OWF39999.1 - 8.2e-08 32.3 0.0 2.7e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain DUF4062 PF13271.6 OWF39999.1 - 1.2e-07 32.0 0.2 9e-07 29.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) WD40 PF00400.32 OWF39999.1 - 3.8e-07 30.7 0.9 0.85 10.6 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat AAA_22 PF13401.6 OWF39999.1 - 1.4e-06 28.6 0.0 4.2e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OWF39999.1 - 0.00014 21.9 0.0 0.00045 20.2 0.0 1.9 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OWF39999.1 - 0.001 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TniB PF05621.11 OWF39999.1 - 0.0077 15.7 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA PF00004.29 OWF39999.1 - 0.019 15.4 0.0 0.057 13.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OWF39999.1 - 0.066 13.1 0.1 0.32 10.9 0.1 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain APAF1_C PF17908.1 OWF39999.1 - 0.099 12.6 0.2 0.6 10.1 0.2 2.4 1 0 0 1 1 1 0 APAF-1 helical domain IATP PF04568.12 OWF39999.1 - 0.1 13.1 0.2 0.29 11.6 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP MFS_1 PF07690.16 OWF40000.1 - 5.5e-22 78.2 42.7 1.5e-12 47.2 11.6 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF40000.1 - 0.0002 20.8 19.9 0.0028 17.0 3.7 2.5 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF443 PF04276.12 OWF40000.1 - 0.027 14.3 0.7 0.027 14.3 0.7 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF443) PCI PF01399.27 OWF40000.1 - 0.17 12.4 0.0 2.3 8.7 0.0 2.1 2 0 0 2 2 2 0 PCI domain COesterase PF00135.28 OWF40001.1 - 9.4e-137 457.0 0.0 1.1e-136 456.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF40001.1 - 5.3e-06 26.4 2.5 0.007 16.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF40001.1 - 0.00071 19.1 0.6 0.0015 18.0 0.6 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OWF40001.1 - 0.019 14.6 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative esterase DUF948 PF06103.11 OWF40002.1 - 0.035 14.4 4.3 0.72 10.1 0.7 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 OWF40002.1 - 0.2 12.3 7.8 0.44 11.2 6.9 2.1 1 1 0 1 1 1 0 SlyX Dor1 PF04124.12 OWF40002.1 - 0.25 10.0 12.2 0.48 9.0 12.2 1.4 1 0 0 1 1 1 0 Dor1-like family DUF1664 PF07889.12 OWF40002.1 - 0.34 11.0 6.7 0.78 9.8 6.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LPP PF04728.13 OWF40002.1 - 0.63 10.5 4.6 8 6.9 0.5 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 OWF40002.1 - 1.9 8.6 6.4 6.8 6.7 6.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-H PF05837.12 OWF40002.1 - 2.1 8.8 20.4 0.16 12.4 11.2 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) IFT57 PF10498.9 OWF40002.1 - 2.3 7.1 22.9 0.025 13.6 15.3 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 bZIP_1 PF00170.21 OWF40002.1 - 5.4 7.2 13.6 1.3 9.1 3.7 3.2 2 1 0 3 3 3 0 bZIP transcription factor DUF4407 PF14362.6 OWF40002.1 - 6.1 6.1 14.4 0.1 12.0 6.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 OWF40002.1 - 9.6 6.7 7.5 54 4.3 6.8 2.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pentapeptide_2 PF01469.18 OWF40003.1 - 0.048 13.6 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) NPV_P10 PF05531.12 OWF40004.1 - 0.0024 18.3 14.7 1.8 9.1 1.7 5.7 4 2 1 5 5 5 2 Nucleopolyhedrovirus P10 protein HrpB7 PF09486.10 OWF40004.1 - 0.0096 16.3 36.2 0.71 10.3 1.5 4.5 1 1 3 4 4 4 3 Bacterial type III secretion protein (HrpB7) Acyl-CoA_dh_2 PF08028.11 OWF40004.1 - 0.12 12.7 6.8 0.81 10.0 0.7 2.5 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain PRKG1_interact PF15898.5 OWF40004.1 - 0.18 12.7 54.9 0.038 14.9 8.7 4.8 3 2 1 4 4 4 0 cGMP-dependent protein kinase interacting domain HOOK PF05622.12 OWF40004.1 - 0.27 9.3 49.9 0.045 11.9 29.7 2.4 1 1 1 2 2 2 0 HOOK protein TACC_C PF05010.14 OWF40004.1 - 0.29 10.9 48.5 0.022 14.6 22.1 3.2 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ERM PF00769.19 OWF40004.1 - 1.6 8.5 53.2 0.19 11.5 24.7 3.1 2 1 1 3 3 3 0 Ezrin/radixin/moesin family LPP PF04728.13 OWF40004.1 - 2.6 8.5 20.6 0.26 11.7 1.8 5.4 6 1 0 6 6 5 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 OWF40004.1 - 2.8 8.0 13.8 0.14 12.2 1.4 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kinase-PPPase PF03618.14 OWF40004.1 - 3.4 7.4 13.4 0.27 11.0 1.9 2.7 2 1 1 3 3 3 0 Kinase/pyrophosphorylase FAM184 PF15665.5 OWF40004.1 - 4.4 7.0 47.5 2.4 7.9 29.6 3.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B zinc_ribbon_16 PF17034.5 OWF40005.1 - 4.8e-22 78.5 16.3 1.2e-21 77.2 16.3 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 OWF40005.1 - 0.00045 19.8 11.4 0.00045 19.8 11.4 3.1 3 1 1 4 4 4 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OWF40005.1 - 0.46 10.4 7.8 5.2 7.0 0.2 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 OWF40005.1 - 8.2 7.5 10.7 3.7 8.6 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat Rep_fac-A_3 PF08661.11 OWF40006.1 - 3.2e-21 75.7 0.1 3.5e-21 75.5 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 zf-C3HC4 PF00097.25 OWF40007.1 - 1.7e-06 27.8 10.3 1.7e-06 27.8 10.3 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF40007.1 - 9.4e-06 25.4 0.0 2.3e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 OWF40007.1 - 2.6e-05 24.3 7.4 2.6e-05 24.3 7.4 3.8 4 0 0 4 4 3 2 B-box zinc finger NHL PF01436.21 OWF40007.1 - 0.00013 21.8 0.3 0.36 11.0 0.0 3.4 3 0 0 3 3 3 2 NHL repeat zf-RING_2 PF13639.6 OWF40007.1 - 0.00086 19.6 10.0 0.00086 19.6 10.0 3.5 3 0 0 3 3 3 1 Ring finger domain SBBP PF06739.11 OWF40007.1 - 0.016 15.1 0.0 0.05 13.6 0.0 1.8 1 0 0 1 1 1 0 Beta-propeller repeat DPBB_1 PF03330.18 OWF40007.1 - 0.2 11.9 0.7 0.55 10.5 0.7 1.8 1 0 0 1 1 1 0 Lytic transglycolase NPV_P10 PF05531.12 OWF40007.1 - 0.21 12.1 2.9 0.23 11.9 0.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NusB PF01029.18 OWF40007.1 - 0.22 11.8 0.8 0.5 10.6 0.8 1.7 1 0 0 1 1 1 0 NusB family zf-RING_UBOX PF13445.6 OWF40007.1 - 0.47 10.5 18.6 0.065 13.3 8.1 3.0 2 0 0 2 2 2 0 RING-type zinc-finger YgaB PF14182.6 OWF40007.1 - 0.7 10.3 4.9 0.65 10.4 1.4 2.4 2 1 1 3 3 3 0 YgaB-like protein 2OG-FeII_Oxy_3 PF13640.6 OWF40008.1 - 2.8e-14 53.8 0.0 7.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RAP1 PF07218.11 OWF40008.1 - 0.25 9.6 9.9 0.44 8.8 9.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ndc1_Nup PF09531.10 OWF40008.1 - 1.1 7.8 6.5 1.6 7.3 6.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 OWF40008.1 - 1.2 7.6 9.0 1.4 7.4 9.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF5383 PF17355.2 OWF40008.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5383) Presenilin PF01080.17 OWF40008.1 - 3.3 6.4 8.4 4.8 5.8 8.4 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 OWF40008.1 - 8.7 4.6 7.7 12 4.1 7.7 1.1 1 0 0 1 1 1 0 Menin FAM117 PF15388.6 OWF40010.1 - 8.9e-64 215.9 5.0 8.9e-64 215.9 5.0 1.9 2 0 0 2 2 2 1 Protein Family FAM117 Peptidase_M22 PF00814.25 OWF40011.1 - 2.8e-78 263.4 0.0 3.5e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family HGTP_anticodon PF03129.20 OWF40012.1 - 1.6e-21 76.3 0.0 6.8e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.20 OWF40012.1 - 9.6e-12 44.9 6.6 3.6e-11 43.0 6.6 2.1 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 OWF40012.1 - 1.3e-10 41.5 0.0 3.1e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Arm PF00514.23 OWF40013.1 - 7.1e-37 124.3 26.3 8.6e-06 25.6 0.2 12.8 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF40013.1 - 1.6e-13 50.8 8.9 0.0058 17.0 0.1 7.7 3 2 6 9 9 9 5 HEAT repeats Ank_2 PF12796.7 OWF40013.1 - 5.2e-12 46.2 5.7 7.9e-05 23.2 0.4 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF40013.1 - 1.7e-10 40.2 9.6 0.055 14.0 0.1 6.1 6 1 1 7 7 4 3 Ankyrin repeat Atx10homo_assoc PF09759.9 OWF40013.1 - 2.1e-06 27.7 14.9 0.29 11.2 0.2 6.7 4 2 3 7 7 7 2 Spinocerebellar ataxia type 10 protein domain Ank_4 PF13637.6 OWF40013.1 - 3e-06 27.7 5.4 0.067 13.8 0.6 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF40013.1 - 2.6e-05 24.4 5.4 0.003 17.8 0.7 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) HEAT PF02985.22 OWF40013.1 - 7.7e-05 22.6 14.0 1.7 9.1 0.0 7.6 8 0 0 8 8 6 1 HEAT repeat Ank PF00023.30 OWF40013.1 - 0.00047 20.5 9.8 0.17 12.4 0.2 5.0 4 0 0 4 4 4 1 Ankyrin repeat KAP PF05804.12 OWF40013.1 - 0.012 13.8 7.6 0.037 12.2 4.5 2.9 2 1 0 2 2 2 0 Kinesin-associated protein (KAP) UNC45-central PF11701.8 OWF40013.1 - 0.014 15.3 0.8 0.83 9.6 0.1 3.4 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 OWF40013.1 - 0.021 15.3 12.5 3.1 8.4 0.1 6.4 6 2 2 8 8 7 0 HEAT-like repeat DUF5584 PF17822.1 OWF40013.1 - 0.13 11.7 2.4 0.26 10.8 0.4 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5584) V-ATPase_H_C PF11698.8 OWF40013.1 - 0.18 12.0 8.8 7.4 6.7 0.1 5.4 4 2 1 5 5 5 0 V-ATPase subunit H IFRD PF05004.13 OWF40013.1 - 0.2 10.7 4.0 10 5.1 0.1 4.1 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) RasGEF_N_2 PF14663.6 OWF40013.1 - 0.28 11.6 3.6 30 5.1 0.1 5.1 5 1 1 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3361 PF11841.8 OWF40013.1 - 0.79 9.7 17.1 1.3 8.9 0.3 5.4 4 1 3 7 7 7 0 Domain of unknown function (DUF3361) MA3 PF02847.17 OWF40014.1 - 2.1e-22 79.2 1.6 2.1e-22 79.2 1.6 2.7 3 0 0 3 3 3 1 MA3 domain Yae1_N PF09811.9 OWF40015.1 - 1.1e-09 37.8 0.2 2.3e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Golgin_A5 PF09787.9 OWF40015.1 - 0.019 14.5 8.3 0.024 14.1 8.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 EMC3_TMCO1 PF01956.16 OWF40015.1 - 0.076 12.7 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like G-alpha PF00503.20 OWF40016.1 - 1.7e-110 369.5 1.8 2.2e-110 369.2 1.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OWF40016.1 - 2.5e-14 53.1 0.8 1.1e-08 34.8 0.3 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF40016.1 - 1.5e-05 24.4 0.7 0.051 12.9 0.5 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OWF40016.1 - 0.045 14.0 0.1 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OWF40016.1 - 0.067 12.9 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OWF40016.1 - 0.069 13.2 0.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 OWF40016.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 OWF40016.1 - 0.2 11.0 0.0 0.49 9.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Xan_ur_permease PF00860.20 OWF40017.1 - 3.2e-79 266.4 28.3 1.1e-78 264.7 28.3 1.7 1 1 0 1 1 1 1 Permease family GCP5-Mod21 PF14609.6 OWF40018.1 - 0.31 9.3 1.2 0.33 9.3 1.2 1.0 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 MRJP PF03022.16 OWF40019.1 - 1.5e-45 155.8 0.6 2.3e-45 155.2 0.6 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 OWF40019.1 - 0.0055 16.3 2.7 4.9 6.7 0.1 3.3 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF40019.1 - 0.14 12.5 1.9 2.2 8.8 0.1 3.4 3 0 0 3 3 3 0 Two component regulator propeller MRJP PF03022.16 OWF40020.1 - 3.3e-33 115.3 0.2 5.1e-33 114.7 0.2 1.2 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 OWF40021.1 - 0.35 11.0 7.0 0.4 10.8 0.0 4.3 6 0 0 6 6 6 0 NHL repeat Gasdermin_C PF17708.1 OWF40022.1 - 0.066 13.3 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Gasdermin PUB domain Na_K-ATPase PF00287.18 OWF40022.1 - 0.25 10.5 2.0 1.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain Sel1 PF08238.12 OWF40023.1 - 0.0012 19.4 0.0 0.0034 18.0 0.0 1.8 1 0 0 1 1 1 1 Sel1 repeat DUF1885 PF08968.10 OWF40023.1 - 0.082 13.0 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Gasdermin_C PF17708.1 OWF40023.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Gasdermin PUB domain Rep_4 PF05797.11 OWF40023.1 - 2.2 7.3 4.5 1.4 8.0 0.9 2.0 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) Pex24p PF06398.11 OWF40023.1 - 10 5.0 11.1 3.7 6.4 5.4 2.5 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin An_peroxidase PF03098.15 OWF40024.1 - 1.6e-168 561.6 0.0 2e-168 561.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Stig1 PF04885.13 OWF40025.1 - 0.035 14.6 6.7 0.064 13.7 6.7 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Toxin_18 PF08087.11 OWF40025.1 - 0.19 11.7 10.3 0.41 10.7 10.3 1.6 1 0 0 1 1 1 0 Conotoxin O-superfamily CBP_BcsO PF17037.5 OWF40025.1 - 0.63 10.2 4.9 0.95 9.6 4.9 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO WBP-1 PF11669.8 OWF40025.1 - 1.8 9.2 17.2 4.3 8.0 14.3 3.0 1 1 0 1 1 1 0 WW domain-binding protein 1 GRIP PF01465.20 OWF40026.1 - 5.7e-11 42.1 0.0 1.9e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 GRIP domain Filament PF00038.21 OWF40026.1 - 0.00064 19.4 51.3 0.00064 19.4 51.3 16.2 3 2 11 14 14 14 7 Intermediate filament protein Nucleos_tra2_C PF07662.13 OWF40027.1 - 1.2e-56 191.9 3.1 1.2e-56 191.9 3.1 2.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF40027.1 - 8.5e-21 74.3 1.7 8.5e-21 74.3 1.7 3.3 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus NACHT PF05729.12 OWF40028.1 - 1.8e-14 54.0 0.0 4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF4062 PF13271.6 OWF40028.1 - 1.9e-11 44.2 0.0 6.6e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) AAA_16 PF13191.6 OWF40028.1 - 2e-08 34.8 0.0 5.5e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF40028.1 - 3.9e-06 27.2 0.0 1.3e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain WD40 PF00400.32 OWF40028.1 - 6.1e-05 23.7 0.1 0.12 13.3 0.2 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat APAF1_C PF17908.1 OWF40028.1 - 0.0012 18.8 0.3 0.0043 17.1 0.3 1.9 1 0 0 1 1 1 1 APAF-1 helical domain PQQ_2 PF13360.6 OWF40028.1 - 0.05 13.2 0.1 8.4 5.9 0.0 3.1 2 1 0 2 2 2 0 PQQ-like domain AAA PF00004.29 OWF40028.1 - 0.057 13.8 0.0 0.5 10.8 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF5046 PF16465.5 OWF40028.1 - 0.11 11.9 0.4 0.69 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) sCache_3_3 PF17202.4 OWF40028.1 - 0.13 12.7 0.0 0.45 11.0 0.0 1.9 1 0 0 1 1 1 0 Single cache domain 3 Peptidase_M19 PF01244.21 OWF40029.1 - 1.5e-108 362.7 0.1 2e-108 362.4 0.1 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF3188 PF11384.8 OWF40029.1 - 0.11 12.2 0.2 0.31 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF3203 PF11462.8 OWF40030.1 - 0.031 14.5 0.7 0.13 12.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) DUF5032 PF16435.5 OWF40030.1 - 0.32 10.4 3.0 0.25 10.8 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5032) BCS1_N PF08740.11 OWF40030.1 - 0.41 10.6 3.2 0.2 11.6 0.6 1.8 2 1 0 2 2 2 0 BCS1 N terminal Dimer_Tnp_hAT PF05699.14 OWF40031.1 - 3.1e-14 52.5 0.1 4.2e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Methyltransf_22 PF13383.6 OWF40032.1 - 4.2e-28 98.6 0.2 8.1e-25 87.8 0.0 2.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_21 PF05050.12 OWF40032.1 - 3.4e-06 27.2 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase FkbM domain NCD1 PF04904.13 OWF40032.1 - 0.095 12.7 0.4 15 5.6 0.0 2.9 3 0 0 3 3 3 0 NAB conserved region 1 (NCD1) Tap-RNA_bind PF09162.10 OWF40033.1 - 3.5e-25 87.6 0.0 6.2e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Tap, RNA-binding TAP_C PF03943.13 OWF40033.1 - 3.5e-21 74.6 1.2 7.2e-21 73.6 1.2 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 OWF40033.1 - 3.4e-10 40.5 0.6 9e-10 39.2 0.6 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 OWF40033.1 - 0.0073 16.7 0.7 0.022 15.2 0.6 1.9 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) UBA_4 PF14555.6 OWF40033.1 - 0.092 12.6 0.8 0.73 9.7 0.1 2.6 3 0 0 3 3 3 0 UBA-like domain MRP-S23 PF10484.9 OWF40034.1 - 7.9e-06 26.1 0.6 0.22 11.8 0.6 3.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Glyco_tranf_2_4 PF13704.6 OWF40034.1 - 7.5e-05 23.2 4.3 2.3 8.8 0.4 4.1 1 1 1 2 2 2 2 Glycosyl transferase family 2 SL4P PF17618.2 OWF40034.1 - 0.00013 22.0 11.6 0.88 9.7 0.5 3.3 1 1 2 3 3 3 3 Uncharacterized Strongylid L4 protein Pox_A3L PF05288.11 OWF40034.1 - 0.0003 20.7 9.8 4 7.5 0.5 4.4 1 1 4 5 5 5 4 Poxvirus A3L Protein DUF5100 PF17029.5 OWF40034.1 - 0.015 15.1 7.6 6.8 6.6 0.4 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5100) Hfq PF17209.3 OWF40034.1 - 0.073 12.7 4.1 7.9 6.2 0.2 3.0 1 1 2 3 3 3 0 Hfq protein Cytokin_check_N PF10407.9 OWF40034.1 - 0.076 13.0 10.8 34 4.5 0.2 5.1 1 1 6 7 7 7 0 Cdc14 phosphatase binding protein N-terminus Adenine_glyco PF03352.13 OWF40034.1 - 0.084 12.6 0.9 0.11 12.2 0.9 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase DUF1848 PF08902.11 OWF40034.1 - 0.12 12.1 2.0 5.4 6.7 2.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1848) Staphostatin_A PF09022.10 OWF40034.1 - 0.12 12.3 18.9 1.4e+04 -4.0 18.9 3.9 1 1 0 1 1 0 0 Staphostatin A Lyase_8_C PF02884.17 OWF40034.1 - 0.21 12.1 18.2 6.4 7.3 1.1 5.0 1 1 4 5 5 5 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain BioT2 PF15368.6 OWF40034.1 - 0.33 10.9 5.0 1.6 8.7 0.3 2.5 1 1 1 2 2 2 0 Spermatogenesis family BioT2 DUF4545 PF15078.6 OWF40034.1 - 0.85 8.5 16.5 9 5.2 3.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4545) NusG PF02357.19 OWF40034.1 - 2.7 8.5 5.7 4.4e+02 1.5 5.7 3.1 1 1 0 1 1 1 0 Transcription termination factor nusG DUF4342 PF14242.6 OWF40034.1 - 5 7.2 5.8 45 4.1 0.3 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4342) Peptidase_C97 PF05903.14 OWF40036.1 - 6.4e-42 142.9 0.0 7.4e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 OWF40036.1 - 0.02 15.2 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF2729 PF10870.8 OWF40036.1 - 0.09 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) E1_dh PF00676.20 OWF40037.1 - 3.6e-102 341.3 0.1 4.4e-102 341.1 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component AAA_7 PF12775.7 OWF40037.1 - 0.00093 18.7 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DXP_synthase_N PF13292.6 OWF40037.1 - 0.0017 17.7 0.0 0.0049 16.1 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OWF40037.1 - 0.014 15.1 1.8 0.031 14.1 0.2 2.2 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain G-patch PF01585.23 OWF40038.1 - 1.8e-16 59.7 1.0 4.2e-16 58.6 1.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OWF40038.1 - 2.5e-07 30.7 0.1 9.2e-07 28.9 0.1 2.0 1 0 0 1 1 1 1 G-patch domain SMODS PF18144.1 OWF40038.1 - 0.038 14.2 0.7 0.07 13.3 0.7 1.5 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DUF4513 PF14983.6 OWF40039.1 - 4.4e-11 43.0 0.3 5.6e-11 42.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4513) Methyltransf_31 PF13847.6 OWF40040.1 - 2.3e-10 40.4 0.5 5.9e-10 39.1 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF40040.1 - 2.7e-08 34.4 0.0 6.5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OWF40040.1 - 1.5e-07 31.1 0.6 2.6e-07 30.3 0.6 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 OWF40040.1 - 1.9e-07 30.7 0.2 3e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OWF40040.1 - 4.5e-07 30.4 0.0 8.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF40040.1 - 1.6e-06 28.8 0.0 3.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF40040.1 - 3.5e-06 26.9 0.0 7.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 OWF40040.1 - 2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Spermine_synth PF01564.17 OWF40040.1 - 3.3e-05 23.4 1.7 7.6e-05 22.2 1.4 1.7 1 1 1 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_9 PF08003.11 OWF40040.1 - 5.3e-05 22.3 0.1 8.1e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.20 OWF40040.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 OWF40040.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 OWF40040.1 - 0.0046 16.5 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OWF40040.1 - 0.0071 16.3 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 OWF40040.1 - 0.012 14.8 0.2 0.019 14.2 0.2 1.2 1 0 0 1 1 1 0 O-methyltransferase DOT1 PF08123.13 OWF40040.1 - 0.047 13.2 3.2 0.58 9.7 1.7 2.7 1 1 1 2 2 2 0 Histone methylation protein DOT1 NOB1_Zn_bind PF08772.11 OWF40040.1 - 0.12 12.5 0.3 0.25 11.5 0.1 1.6 2 0 0 2 2 1 0 Nin one binding (NOB1) Zn-ribbon like HA2 PF04408.23 OWF40041.1 - 3.1e-20 72.5 5.4 2.2e-19 69.7 0.0 3.3 2 1 1 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OWF40041.1 - 3.9e-18 65.6 0.0 8.5e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OWF40041.1 - 3.4e-14 53.1 0.0 9.2e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 OWF40041.1 - 9.7e-13 48.4 0.2 9.7e-13 48.4 0.2 2.3 2 0 0 2 2 2 1 RWD domain DEAD PF00270.29 OWF40041.1 - 5.6e-11 42.5 0.2 1.1e-10 41.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Torus PF16131.5 OWF40041.1 - 2.2e-05 25.1 0.1 2.2e-05 25.1 0.1 2.4 2 0 0 2 2 1 1 Torus domain zf-CCCH_4 PF18044.1 OWF40041.1 - 4.5e-05 23.1 6.7 8.7e-05 22.2 6.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_19 PF13245.6 OWF40041.1 - 0.0001 22.7 0.1 0.00024 21.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain zf-CCCH PF00642.24 OWF40041.1 - 0.00031 20.6 5.5 0.00061 19.6 5.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_22 PF13401.6 OWF40041.1 - 0.00045 20.5 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OWF40041.1 - 0.001 19.1 0.1 0.016 15.2 0.1 2.9 2 1 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 OWF40041.1 - 0.01 15.8 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OWF40041.1 - 0.012 14.7 0.0 0.031 13.3 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 OWF40041.1 - 0.04 13.6 0.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain zf-CCCH_2 PF14608.6 OWF40041.1 - 0.082 13.4 6.2 0.16 12.5 6.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 OWF40041.1 - 0.42 10.7 15.1 0.079 13.1 10.7 2.1 2 0 0 2 2 2 0 Zinc finger domain SpoIISB_antitox PF14185.6 OWF40041.1 - 0.48 10.3 2.4 1.3 9.0 1.0 2.5 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system TTL PF03133.15 OWF40042.1 - 2.7e-19 69.4 0.0 1.3e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family RimK PF08443.11 OWF40042.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 OWF40042.1 - 0.14 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain RNA_pol_Rpb8 PF03870.15 OWF40043.1 - 2.2e-53 180.2 0.0 2.5e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OWF40043.1 - 2.3e-05 24.4 0.0 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Dor1 PF04124.12 OWF40044.1 - 2.4e-79 266.5 8.1 3.6e-79 265.9 8.1 1.2 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 OWF40044.1 - 0.0046 17.0 0.2 0.015 15.3 0.2 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 OWF40044.1 - 0.0084 15.9 2.0 0.015 15.1 2.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.14 OWF40044.1 - 0.053 13.4 0.8 0.15 11.9 0.8 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 OWF40044.1 - 0.099 11.9 6.8 0.16 11.2 6.8 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DUF600 PF04634.12 OWF40044.1 - 0.34 11.0 2.6 0.27 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF600 G_glu_transpept PF01019.21 OWF40045.1 - 7.7e-172 572.6 0.0 8.8e-172 572.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase zf-B_box PF00643.24 OWF40046.1 - 0.0001 22.4 6.4 0.0002 21.4 6.4 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 OWF40046.1 - 0.002 18.3 6.0 0.0056 16.8 4.0 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Sdh_cyt PF01127.22 OWF40047.1 - 9.3e-26 90.2 1.3 1.2e-25 89.9 1.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SKG6 PF08693.10 OWF40047.1 - 1.1 8.7 10.1 0.13 11.7 1.5 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Tetraspanin PF00335.20 OWF40048.1 - 2.6e-17 63.3 41.6 1.9e-10 40.9 9.3 3.7 3 1 0 3 3 3 3 Tetraspanin family Galactosyl_T PF01762.21 OWF40049.1 - 1.6e-52 178.2 0.6 2e-52 177.8 0.6 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF40049.1 - 1.9e-06 27.5 0.4 3.3e-06 26.7 0.4 1.3 1 0 0 1 1 1 1 Fringe-like DUF1837 PF08878.11 OWF40049.1 - 0.039 13.7 2.5 0.049 13.4 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1837) Galactosyl_T PF01762.21 OWF40050.1 - 1.4e-52 178.4 0.2 1.9e-52 177.9 0.2 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF40050.1 - 4.2e-05 23.1 0.5 9.8e-05 21.9 0.5 1.6 1 1 0 1 1 1 1 Fringe-like Lectin_C PF00059.21 OWF40051.1 - 0.00028 21.6 0.6 0.0005 20.8 0.1 1.7 2 0 0 2 2 2 1 Lectin C-type domain Rogdi_lz PF10259.9 OWF40052.1 - 0.098 12.1 7.2 2.6 7.4 7.2 2.0 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein Exonuc_VII_L PF02601.15 OWF40052.1 - 0.68 9.4 14.0 0.91 9.0 14.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 OWF40052.1 - 5.2 7.2 33.9 0.6 10.3 14.1 3.1 1 1 2 3 3 3 0 Tropomyosin like DUF489 PF04356.12 OWF40052.1 - 6.2 6.8 10.8 2.1 8.3 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) ALMT PF11744.8 OWF40052.1 - 8.5 5.1 14.8 9.5 4.9 14.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ank_2 PF12796.7 OWF40053.1 - 4.5e-19 68.8 1.0 2.3e-05 24.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF40053.1 - 1.8e-14 53.4 1.2 0.0001 22.5 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OWF40053.1 - 5.5e-14 52.3 0.2 0.0012 19.4 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF40053.1 - 4e-11 42.1 1.1 4.8 8.1 0.1 6.0 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF40053.1 - 2.2e-10 40.5 1.7 0.0024 18.2 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ig_3 PF13927.6 OWF40054.1 - 1.1e-50 170.1 13.6 5.7e-13 49.3 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 OWF40054.1 - 3.3e-37 126.4 4.6 7.4e-10 38.8 0.0 6.2 5 3 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF40054.1 - 4.2e-37 126.3 12.2 8.7e-09 35.6 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 OWF40054.1 - 4.8e-29 100.4 5.9 6.4e-07 29.5 0.1 5.9 5 2 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 OWF40054.1 - 1.5e-15 57.3 6.8 2.5e-05 24.4 0.6 6.3 4 3 1 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF40054.1 - 9.3e-15 54.5 8.5 1.6e-09 37.7 0.0 6.4 7 1 0 7 7 6 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF40054.1 - 1.1e-07 32.1 1.8 2.4 8.6 0.0 6.0 5 2 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 OWF40054.1 - 1.2e-07 32.0 4.4 0.037 14.4 0.0 5.1 6 0 0 6 6 6 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 OWF40054.1 - 1.2e-06 28.5 0.0 0.046 13.8 0.0 3.7 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 OWF40054.1 - 2.8e-05 24.3 4.5 5 7.5 0.0 5.9 6 1 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 OWF40054.1 - 0.002 17.6 0.0 2.1 8.0 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Syndecan PF01034.20 OWF40054.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 OWF40054.1 - 7.5 6.4 6.2 20 5.1 6.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 APC_u13 PF16634.5 OWF40055.1 - 0.5 10.3 4.0 20 5.2 0.7 4.0 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr and SAMP DUF3948 PF13134.6 OWF40055.1 - 0.64 9.8 3.5 3.4e+02 1.0 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF3948) BRD4_CDT PF17105.5 OWF40056.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 SelK_SelG PF10961.8 OWF40056.1 - 2.3 8.9 4.4 1e+02 3.6 0.0 3.4 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Ribosomal_L29 PF00831.23 OWF40056.1 - 2.5 8.1 4.7 0.8 9.7 0.6 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein Dehydrin PF00257.19 OWF40056.1 - 2.7 8.5 7.5 5 7.6 0.1 2.2 2 0 0 2 2 2 0 Dehydrin DUF916 PF06030.12 OWF40058.1 - 6.7e-07 29.4 3.6 2.8 8.0 0.1 4.9 1 1 5 6 6 6 2 Bacterial protein of unknown function (DUF916) KORA PF16509.5 OWF40058.1 - 9.6e-06 25.8 12.3 22 5.4 0.1 7.6 1 1 8 10 10 10 0 TrfB plasmid transcriptional repressor Dec-1 PF04624.14 OWF40058.1 - 1.2e-05 25.0 12.4 1.7e+02 2.2 0.0 10.1 11 0 0 11 11 11 0 Dec-1 repeat PBP5_C PF07943.13 OWF40058.1 - 2.6e-05 24.4 0.2 0.8 10.0 0.2 4.3 1 1 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain RHH_1 PF01402.21 OWF40058.1 - 3.3e-05 23.7 5.4 3.7e+02 1.3 0.0 9.5 12 0 0 12 12 12 0 Ribbon-helix-helix protein, copG family MdcG PF10620.9 OWF40058.1 - 3.4e-05 23.7 2.7 0.62 9.8 1.1 3.5 1 1 1 2 2 2 2 Phosphoribosyl-dephospho-CoA transferase MdcG PS-DH PF14765.6 OWF40058.1 - 7e-05 22.2 5.9 0.22 10.7 0.8 3.7 1 1 1 2 2 2 2 Polyketide synthase dehydratase Casc1 PF12366.8 OWF40058.1 - 0.00026 20.6 0.2 0.54 9.7 0.1 3.1 1 1 1 2 2 2 2 Cancer susceptibility candidate 1 IalB PF06776.12 OWF40058.1 - 0.0026 17.8 0.0 0.71 9.9 0.0 2.5 1 1 1 2 2 2 2 Invasion associated locus B (IalB) protein GP46 PF07409.12 OWF40058.1 - 0.019 14.7 1.9 39 4.0 0.1 3.5 1 1 3 5 5 5 0 Phage protein GP46 Type_III_YscX PF09474.10 OWF40058.1 - 0.041 14.2 7.3 11 6.4 0.2 3.4 1 1 1 3 3 3 0 Type III secretion system YscX (type_III_YscX) DUF1583 PF07622.11 OWF40058.1 - 0.3 9.8 2.9 3.1 6.5 0.5 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1583) BBS2_C PF14782.6 OWF40058.1 - 0.71 8.6 10.5 7.3 5.2 7.7 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal YukD PF08817.10 OWF40058.1 - 0.91 10.3 7.3 1.3e+02 3.4 0.9 5.0 1 1 3 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD Tet_res_leader PF08050.12 OWF40058.1 - 3.2 7.7 15.7 5e+02 0.6 0.0 8.7 11 0 0 11 11 11 0 Tetracycline resistance leader peptide Gemini_AL1 PF00799.20 OWF40058.1 - 8.4 6.8 22.1 26 5.2 0.8 5.0 1 1 4 5 5 5 0 Geminivirus Rep catalytic domain Ig_3 PF13927.6 OWF40059.1 - 1e-84 279.2 14.2 1.8e-09 38.0 0.0 9.6 9 0 0 9 9 9 9 Immunoglobulin domain I-set PF07679.16 OWF40059.1 - 4.6e-73 241.4 4.8 6.5e-10 38.9 0.2 9.4 9 0 0 9 9 9 9 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF40059.1 - 2e-60 201.1 8.3 1.2e-06 28.7 0.0 9.4 9 0 0 9 9 9 9 Immunoglobulin domain C2-set_2 PF08205.12 OWF40059.1 - 1.1e-46 156.8 6.4 7.7e-09 35.5 0.1 7.3 7 0 0 7 7 7 5 CD80-like C2-set immunoglobulin domain ig PF00047.25 OWF40059.1 - 1.4e-44 150.1 15.0 1.1e-06 28.7 0.1 9.3 10 0 0 10 10 10 7 Immunoglobulin domain C1-set PF07654.15 OWF40059.1 - 5.1e-20 71.6 2.5 4.9e-05 23.6 0.1 6.8 7 0 0 7 7 7 3 Immunoglobulin C1-set domain V-set PF07686.17 OWF40059.1 - 1.6e-17 63.7 14.0 0.37 11.0 0.0 11.1 9 5 1 10 10 10 5 Immunoglobulin V-set domain fn3 PF00041.21 OWF40059.1 - 2.4e-09 37.4 0.0 1.6e-08 34.8 0.0 2.6 1 0 0 1 1 1 1 Fibronectin type III domain Ig_C17orf99 PF17736.1 OWF40059.1 - 2.1e-08 34.1 1.4 1.9 8.6 0.0 7.4 8 0 0 8 8 8 2 C17orf99 Ig domain Ig_4 PF16680.5 OWF40059.1 - 2.2e-07 31.0 15.5 0.43 10.9 0.0 8.4 8 2 1 9 9 8 2 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 OWF40059.1 - 0.0027 17.8 1.6 1.8 8.8 0.0 4.5 6 0 0 6 6 5 1 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 OWF40059.1 - 0.031 14.1 0.3 41 4.0 0.0 4.6 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 EphA2_TM PF14575.6 OWF40059.1 - 0.09 13.7 0.8 0.75 10.7 0.8 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OWF40059.1 - 1.2 8.6 6.0 0.63 9.5 3.7 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain zf-RING_2 PF13639.6 OWF40060.1 - 2.6e-11 43.7 8.6 2.6e-11 43.7 8.6 2.2 2 0 0 2 2 2 1 Ring finger domain TPR_1 PF00515.28 OWF40060.1 - 1.2e-09 37.6 13.5 0.0057 16.4 0.4 5.2 6 0 0 6 6 4 3 Tetratricopeptide repeat zf-rbx1 PF12678.7 OWF40060.1 - 1.5e-08 34.8 6.0 1.5e-08 34.8 6.0 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OWF40060.1 - 7.8e-08 32.0 8.5 7.8e-08 32.0 8.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.6 OWF40060.1 - 1.3e-07 32.1 2.9 6.7e-06 26.7 0.2 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF40060.1 - 3.7e-07 29.9 2.2 1.8 9.0 0.0 4.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF40060.1 - 5e-07 29.3 8.6 0.13 12.0 0.5 5.3 3 1 2 5 5 5 3 TPR repeat zf-C3HC4 PF00097.25 OWF40060.1 - 5.4e-07 29.4 8.6 1.2e-06 28.2 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.6 OWF40060.1 - 6.4e-07 29.8 2.5 0.27 11.8 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat zf-RING_11 PF17123.5 OWF40060.1 - 7e-07 28.9 2.9 2.9e-06 26.9 2.9 2.1 1 0 0 1 1 1 1 RING-like zinc finger TPR_2 PF07719.17 OWF40060.1 - 7.7e-06 25.6 12.4 0.027 14.6 0.2 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 OWF40060.1 - 1.8e-05 24.6 4.0 4.6e-05 23.4 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF40060.1 - 2.6e-05 24.0 5.5 5.8e-05 22.9 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_17 PF13431.6 OWF40060.1 - 5.6e-05 23.2 1.8 0.028 14.8 0.5 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 OWF40060.1 - 0.0002 21.4 0.7 0.00054 20.0 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_12 PF13424.6 OWF40060.1 - 0.00032 20.9 4.8 0.031 14.6 0.1 4.0 4 1 0 4 4 3 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 OWF40060.1 - 0.0014 18.5 6.3 0.0033 17.3 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ANAPC3 PF12895.7 OWF40060.1 - 0.0022 18.2 1.1 0.0094 16.2 0.1 2.5 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Zn_ribbon_17 PF17120.5 OWF40060.1 - 0.028 14.0 4.2 0.055 13.1 4.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 OWF40060.1 - 0.037 14.2 4.3 0.11 12.6 4.3 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 TPR_7 PF13176.6 OWF40060.1 - 0.037 14.1 2.0 6.5 7.0 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF40060.1 - 0.35 11.8 2.7 77 4.5 0.0 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 OWF40060.1 - 0.83 9.6 4.7 1.6 8.7 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 OWF40060.1 - 1.1 9.6 16.8 0.46 10.8 7.0 2.6 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 OWF40060.1 - 2.1 8.6 5.4 7 6.9 5.4 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OWF40060.1 - 2.8 7.8 6.9 8.4 6.3 6.9 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 OWF40060.1 - 4.8 7.4 8.0 11 6.2 8.0 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 OWF40060.1 - 4.8 7.4 12.7 0.37 11.0 4.5 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 OWF40060.1 - 6.7 7.0 9.6 24 5.3 1.9 2.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain WD40 PF00400.32 OWF40061.1 - 2.8e-12 47.0 14.3 0.00021 22.0 1.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF40061.1 - 1.1e-08 35.2 0.0 0.0051 17.1 0.0 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OWF40061.1 - 0.00066 18.1 0.1 0.0011 17.3 0.1 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz p450 PF00067.22 OWF40062.1 - 2.4e-102 343.1 0.0 2.8e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF40063.1 - 2.8e-99 333.0 0.0 3.2e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fibrillarin PF01269.17 OWF40065.1 - 9e-109 361.9 0.1 1.1e-108 361.6 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OWF40065.1 - 2.6e-06 27.3 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OWF40065.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 OWF40065.1 - 0.028 14.1 0.0 0.073 12.7 0.0 1.6 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OWF40065.1 - 0.064 13.4 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase TNF PF00229.18 OWF40066.1 - 6.4e-09 35.8 0.1 1.2e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF40066.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 C1q domain GFO_IDH_MocA PF01408.22 OWF40067.1 - 2.6e-18 67.0 0.0 4.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OWF40067.1 - 2.4e-05 24.3 0.0 7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain EcoRI PF02963.16 OWF40067.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRI MFS_1 PF07690.16 OWF40068.1 - 7.2e-26 90.9 24.1 2.4e-14 53.0 0.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF40068.1 - 0.0032 16.4 7.8 0.0032 16.4 7.8 3.3 2 1 1 3 3 3 1 MFS_1 like family DUF3499 PF12005.8 OWF40070.1 - 2.5 8.7 6.9 9.1 6.9 5.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) Pep_M12B_propep PF01562.19 OWF40070.1 - 2.6 8.3 4.7 3.7 7.8 1.6 2.4 1 1 1 2 2 2 0 Reprolysin family propeptide SPRY PF00622.28 OWF40071.1 - 7.7e-16 58.3 0.0 9.3e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 SPRY domain MFS_1 PF07690.16 OWF40072.1 - 1.9e-28 99.4 35.7 1.2e-16 60.6 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 OWF40072.1 - 0.0019 17.3 8.4 0.0019 17.3 8.4 2.5 2 1 0 2 2 2 1 PUCC protein PIRT PF15099.6 OWF40072.1 - 2 8.0 4.1 3.5 7.2 0.1 3.0 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Carboxyl_trans PF01039.22 OWF40073.1 - 1.1e-197 657.6 0.1 1.3e-197 657.4 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 OWF40073.1 - 0.00082 18.9 0.2 0.021 14.3 0.0 2.7 2 1 1 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Glyco_transf_11 PF01531.16 OWF40074.1 - 2.3e-33 115.7 0.6 4.6e-33 114.7 0.6 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 11 Mucin PF01456.17 OWF40074.1 - 0.16 12.0 8.3 0.27 11.2 8.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_transf_11 PF01531.16 OWF40075.1 - 4.1e-33 114.9 1.8 6.5e-33 114.2 1.8 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 11 Glyco_transf_11 PF01531.16 OWF40076.1 - 3.3e-34 118.4 1.2 4e-34 118.2 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 Myelin_MBP PF01669.17 OWF40076.1 - 0.048 14.3 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 Myelin basic protein ABC_membrane PF00664.23 OWF40077.1 - 2.2e-65 221.0 35.5 1.1e-40 140.0 4.9 3.7 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF40077.1 - 2.3e-53 180.4 2.3 5.7e-30 104.6 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OWF40077.1 - 4.1e-11 42.8 5.5 0.00017 21.1 0.1 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OWF40077.1 - 1.1e-05 25.5 1.8 0.093 12.8 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase MTABC_N PF16185.5 OWF40077.1 - 1.1e-05 25.0 5.2 1.1e-05 25.0 5.2 2.7 3 0 0 3 3 3 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_16 PF13191.6 OWF40077.1 - 2.9e-05 24.5 0.1 0.2 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OWF40077.1 - 0.00031 20.4 0.6 0.41 10.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OWF40077.1 - 0.0018 18.2 1.6 0.28 11.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_ATPase PF09818.9 OWF40077.1 - 0.0027 16.6 0.6 0.045 12.6 0.0 2.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class Dynamin_N PF00350.23 OWF40077.1 - 0.0082 16.2 5.2 0.014 15.5 0.1 2.9 3 0 0 3 3 2 1 Dynamin family TrwB_AAD_bind PF10412.9 OWF40077.1 - 0.0084 15.1 0.2 2 7.2 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 OWF40077.1 - 0.01 14.9 0.3 0.79 8.7 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_21 PF13304.6 OWF40077.1 - 0.012 15.4 2.6 2.9 7.6 0.5 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 OWF40077.1 - 0.02 14.1 1.4 0.88 8.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 OWF40077.1 - 0.024 14.9 0.7 13 6.1 0.1 3.5 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 OWF40077.1 - 0.031 14.4 7.3 0.3 11.1 0.5 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 OWF40077.1 - 0.068 12.3 1.4 2.4 7.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 OWF40077.1 - 0.071 12.8 0.1 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OWF40077.1 - 0.081 12.1 0.9 4.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OWF40077.1 - 0.087 12.3 0.1 5.2 6.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OWF40077.1 - 0.094 12.4 1.5 12 5.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 OWF40077.1 - 0.16 12.2 0.4 25 5.1 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OWF40077.1 - 0.17 11.5 1.0 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 OWF40077.1 - 0.18 11.3 0.4 12 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OWF40077.1 - 0.35 11.4 11.1 2.9 8.3 0.0 3.6 3 1 0 3 3 2 0 AAA domain DUF4017 PF13209.6 OWF40077.1 - 0.41 10.6 4.7 3.8 7.5 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) AAA_15 PF13175.6 OWF40077.1 - 1.4 8.6 5.9 2.7 7.6 0.1 3.0 4 0 0 4 4 3 0 AAA ATPase domain CTP_transf_1 PF01148.20 OWF40078.1 - 2.2e-84 283.4 27.2 2.7e-84 283.1 27.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family MCU PF04678.13 OWF40079.1 - 3.9e-62 209.4 0.2 5.1e-62 209.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter ER_lumen_recept PF00810.18 OWF40080.1 - 2.5e-54 184.1 10.6 2.5e-54 184.1 10.6 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PTEN_C2 PF10409.9 OWF40081.1 - 2.6e-32 111.4 0.8 4e-32 110.8 0.8 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OWF40081.1 - 2e-06 27.7 0.0 7.2e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF40081.1 - 0.0021 18.1 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OWF40081.1 - 0.0041 16.7 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF40081.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate SWIRM-assoc_1 PF16495.5 OWF40083.1 - 0.1 12.6 5.4 3.9 7.5 0.3 2.9 1 1 2 3 3 3 0 SWIRM-associated region 1 DUF3552 PF12072.8 OWF40083.1 - 0.11 12.0 6.9 1 8.8 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CENP-F_leu_zip PF10473.9 OWF40083.1 - 0.11 12.5 3.3 0.28 11.2 3.3 1.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0449 PF15136.6 OWF40083.1 - 0.47 10.9 11.9 1 9.9 4.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 SKA2 PF16740.5 OWF40083.1 - 0.6 9.9 8.5 2.5 7.9 1.7 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 FliD_N PF02465.18 OWF40083.1 - 3.2 8.5 19.5 2.6 8.8 4.9 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus pXO2-34 PF17362.2 OWF40083.1 - 3.8 7.4 21.7 2.9 7.8 3.6 3.5 1 1 3 4 4 4 0 Family of unknown function CTP_transf_3 PF02348.19 OWF40083.1 - 5.8 6.8 14.2 2e+02 1.8 14.1 2.1 1 1 0 1 1 1 0 Cytidylyltransferase SecA_SW PF07516.13 OWF40084.1 - 0.61 10.1 12.5 11 6.0 5.2 3.7 1 1 1 2 2 2 0 SecA Wing and Scaffold domain SRF-TF PF00319.18 OWF40084.1 - 0.8 9.2 16.3 5 6.7 0.2 4.6 2 1 2 4 4 4 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Ste5 PF11610.8 OWF40084.1 - 1.6 8.7 5.9 69 3.4 0.2 5.4 3 2 3 6 6 6 0 Scaffold protein Ste5, Fus3-binding region RBM1CTR PF08081.11 OWF40084.1 - 7.2 6.8 10.4 46 4.2 3.6 3.7 2 1 1 3 3 3 0 RBM1CTR (NUC064) family 7tm_1 PF00001.21 OWF40085.1 - 3.2e-55 187.3 23.3 3.2e-55 187.3 23.3 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF40085.1 - 7.5e-11 41.9 22.4 1.2e-10 41.3 22.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF40085.1 - 3e-08 33.6 26.5 9.7e-08 31.9 26.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF40085.1 - 0.00057 19.7 16.0 0.00092 19.0 16.0 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 OWF40085.1 - 0.0063 15.8 22.8 0.039 13.2 22.7 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw MRAP PF15183.6 OWF40085.1 - 0.36 10.8 5.3 7 6.7 0.1 3.5 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Synaptobrevin PF00957.21 OWF40086.1 - 2.5e-24 84.9 2.4 3.5e-24 84.4 2.4 1.2 1 0 0 1 1 1 1 Synaptobrevin LAP1C PF05609.12 OWF40086.1 - 0.0023 17.1 1.0 0.0029 16.8 1.0 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) T2SSF PF00482.23 OWF40086.1 - 0.029 14.3 0.5 0.11 12.4 0.5 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Synaptobrevin PF00957.21 OWF40089.1 - 0.31 10.9 1.3 0.6 9.9 1.3 1.4 1 0 0 1 1 1 0 Synaptobrevin IRK_C PF17655.1 OWF40090.1 - 7.4e-49 165.7 0.0 9.8e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OWF40090.1 - 5.6e-44 149.4 4.2 5.6e-44 149.4 4.2 1.5 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OWF40090.1 - 0.04 13.9 7.8 0.12 12.3 7.8 1.9 1 1 0 1 1 1 0 Ion channel Calx-beta PF03160.14 OWF40090.1 - 0.16 12.2 0.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Calx-beta domain Prefoldin_2 PF01920.20 OWF40091.1 - 8.4e-05 22.5 5.4 0.00012 22.0 5.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF4376 PF14301.6 OWF40091.1 - 0.084 13.2 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) YkyA PF10368.9 OWF40091.1 - 0.19 11.4 7.6 0.088 12.5 2.8 2.0 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein RAI1 PF08652.11 OWF40092.1 - 8e-22 77.2 0.2 1.9e-21 76.0 0.1 1.8 1 1 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Stk19 PF10494.9 OWF40093.1 - 7.8e-35 120.7 0.0 1.2e-34 120.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 SIR2_2 PF13289.6 OWF40093.1 - 0.056 13.6 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 SIR2-like domain Ependymin PF00811.18 OWF40094.1 - 1.1e-07 32.2 0.1 2.4e-07 31.1 0.1 1.5 1 1 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF40095.1 - 1.4e-10 41.5 0.1 9.7e-10 38.8 0.1 2.0 1 1 0 1 1 1 1 Ependymin QVR PF17064.5 OWF40096.1 - 1.3e-06 28.5 9.8 1.7e-06 28.2 9.8 1.1 1 0 0 1 1 1 1 Sleepless protein QVR PF17064.5 OWF40097.1 - 3.4e-07 30.4 3.2 6e-07 29.6 3.2 1.4 1 0 0 1 1 1 1 Sleepless protein DUF753 PF05444.12 OWF40097.1 - 0.7 9.9 6.9 7.9 6.5 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF753) EF_assoc_2 PF08356.12 OWF40098.1 - 3.8e-33 113.3 0.0 1.2e-32 111.7 0.0 2.0 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 OWF40098.1 - 4e-27 93.6 2.0 2.7e-26 90.9 0.7 2.3 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 OWF40098.1 - 3.7e-25 88.4 0.0 8.4e-20 71.0 0.0 2.7 2 1 0 2 2 2 2 Ras family Roc PF08477.13 OWF40098.1 - 1.3e-13 51.3 0.0 1.4e-10 41.5 0.0 3.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 OWF40098.1 - 4.9e-07 29.2 0.2 7.1e-05 22.4 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain MMR_HSR1 PF01926.23 OWF40098.1 - 7.6e-07 29.2 0.0 0.001 19.1 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF40098.1 - 9.9e-07 28.8 1.1 0.71 9.8 0.0 4.9 5 1 1 6 6 5 1 RsgA GTPase EF-hand_1 PF00036.32 OWF40098.1 - 1.9e-06 27.0 1.3 0.00017 20.9 0.1 2.7 2 0 0 2 2 2 1 EF hand AAA_22 PF13401.6 OWF40098.1 - 3.2e-06 27.5 0.1 0.0048 17.2 0.0 3.6 3 1 0 3 3 3 1 AAA domain EF-hand_7 PF13499.6 OWF40098.1 - 6.3e-06 26.6 0.2 0.012 16.0 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair AAA_16 PF13191.6 OWF40098.1 - 1.1e-05 25.9 0.0 0.0021 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Arf PF00025.21 OWF40098.1 - 2.1e-05 24.0 0.0 0.00062 19.3 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF40098.1 - 4.5e-05 23.0 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OWF40098.1 - 0.00022 21.1 5.6 0.35 10.6 0.1 4.0 3 1 0 4 4 4 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OWF40098.1 - 0.00032 21.3 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OWF40098.1 - 0.00044 20.0 0.1 2 8.2 0.0 3.1 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OWF40098.1 - 0.00054 20.4 0.0 0.012 16.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OWF40098.1 - 0.00056 19.5 0.0 0.092 12.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 OWF40098.1 - 0.00066 20.2 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 OWF40098.1 - 0.0012 18.9 0.0 0.03 14.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OWF40098.1 - 0.0015 18.3 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OWF40098.1 - 0.0017 18.3 0.0 0.85 9.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Septin PF00735.18 OWF40098.1 - 0.0019 17.6 0.1 0.28 10.4 0.0 2.7 3 0 0 3 3 3 1 Septin AAA_33 PF13671.6 OWF40098.1 - 0.0019 18.4 0.1 1.1 9.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OWF40098.1 - 0.0043 16.8 0.3 3.9 7.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SPARC_Ca_bdg PF10591.9 OWF40098.1 - 0.0047 17.2 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region MCM PF00493.23 OWF40098.1 - 0.0053 15.9 0.0 0.035 13.2 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain RNA_helicase PF00910.22 OWF40098.1 - 0.0073 16.7 0.0 7.2 7.1 0.0 3.3 4 0 0 4 4 2 0 RNA helicase G-alpha PF00503.20 OWF40098.1 - 0.0081 15.4 0.7 1.9 7.5 0.1 3.3 3 1 1 4 4 4 1 G-protein alpha subunit EF-hand_5 PF13202.6 OWF40098.1 - 0.0096 15.4 0.1 0.051 13.1 0.1 2.2 1 0 0 1 1 1 1 EF hand AAA_25 PF13481.6 OWF40098.1 - 0.0096 15.5 0.0 0.092 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.9 OWF40098.1 - 0.01 15.1 0.6 2.3 7.3 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 OWF40098.1 - 0.013 15.5 0.0 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 OWF40098.1 - 0.04 13.4 0.1 6.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 OWF40098.1 - 0.058 12.7 0.0 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 OWF40098.1 - 0.16 12.2 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OWF40098.1 - 0.18 11.7 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 NTPase ANAPC4_WD40 PF12894.7 OWF40099.1 - 2.9e-13 49.9 0.0 2.5e-05 24.5 0.0 4.1 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF40099.1 - 2.4e-10 40.8 8.5 0.056 14.3 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat WD40_like PF17005.5 OWF40099.1 - 0.0046 16.3 0.4 0.37 10.1 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain DUF1836 PF08876.11 OWF40101.1 - 0.091 12.8 5.1 0.23 11.5 4.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1836) EphA2_TM PF14575.6 OWF40102.1 - 0.018 15.9 0.0 0.06 14.2 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 OWF40102.1 - 0.026 14.9 0.3 0.057 13.8 0.3 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Stevor PF17410.2 OWF40102.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 OWF40102.1 - 4.5 6.8 9.3 8.9 5.8 9.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RCR PF12273.8 OWF40102.1 - 4.7 7.9 14.8 9.4e+02 0.5 14.8 3.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Amino_oxidase PF01593.24 OWF40103.1 - 9e-60 203.2 0.0 1.1e-59 203.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF40103.1 - 3.2e-12 46.5 0.0 6.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF40103.1 - 1.4e-08 34.3 0.3 6.9e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OWF40103.1 - 1.1e-07 31.7 0.2 2.9e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF40103.1 - 0.00014 21.0 0.5 0.0046 16.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OWF40103.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF40103.1 - 0.00044 19.1 0.9 0.038 12.7 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 OWF40103.1 - 0.00048 19.5 0.1 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF40103.1 - 0.002 17.6 0.0 0.0056 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.15 OWF40103.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 OWF40103.1 - 0.024 14.6 1.0 0.081 12.9 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OWF40103.1 - 0.028 15.0 0.6 0.37 11.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF40103.1 - 0.031 13.4 0.8 0.2 10.7 0.1 2.3 2 1 1 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 OWF40103.1 - 0.089 11.6 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 OWF40103.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family Amino_oxidase PF01593.24 OWF40104.1 - 1.2e-40 140.2 0.0 1.5e-40 139.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase zf-B_box PF00643.24 OWF40105.1 - 3.1e-15 56.0 17.3 3.9e-09 36.5 4.2 2.7 2 0 0 2 2 2 2 B-box zinc finger Fez1 PF06818.15 OWF40105.1 - 0.0017 18.9 9.6 0.003 18.0 9.6 1.3 1 0 0 1 1 1 1 Fez1 EzrA PF06160.12 OWF40105.1 - 0.035 12.3 8.4 0.051 11.8 8.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF713 PF05218.14 OWF40105.1 - 0.041 13.6 5.2 0.064 13.0 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF713) YabA PF06156.13 OWF40105.1 - 0.068 13.8 3.2 0.22 12.2 3.2 1.9 1 1 0 1 1 1 0 Initiation control protein YabA IBR PF01485.21 OWF40105.1 - 0.76 10.1 14.8 0.79 10.0 1.6 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain TMPIT PF07851.13 OWF40105.1 - 2.6 7.2 7.8 94 2.1 8.4 2.6 2 1 0 2 2 2 0 TMPIT-like protein SAS4 PF15460.6 OWF40105.1 - 8.6 6.5 10.2 2.7 8.2 1.5 3.1 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 Mab-21 PF03281.14 OWF40106.1 - 1.5e-34 119.6 0.7 2.4e-34 119.0 0.7 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_2 PF07719.17 OWF40106.1 - 0.032 14.3 0.1 3.4 8.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SPT_ssu-like PF11779.8 OWF40106.1 - 0.39 10.4 2.5 13 5.5 0.7 2.5 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like SPRR2 PF14820.6 OWF40107.1 - 0.002 18.2 62.1 0.087 12.9 13.2 4.0 1 1 3 4 4 4 4 Small proline-rich 2 Extensin_2 PF04554.13 OWF40107.1 - 2.5 8.3 31.3 62 3.8 10.3 3.5 1 1 2 3 3 3 0 Extensin-like region Mab-21 PF03281.14 OWF40108.1 - 4e-32 111.7 0.2 5.8e-32 111.2 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF40108.1 - 0.0087 16.3 0.1 0.48 10.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF40108.1 - 0.028 14.2 0.0 6.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF40108.1 - 0.034 14.3 0.1 0.95 9.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 OWF40109.1 - 0.0047 16.3 0.0 0.0052 16.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase 7tm_7 PF08395.12 OWF40110.1 - 2.4e-19 69.8 28.8 2.8e-19 69.6 28.8 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Trehalose_recp PF06151.13 OWF40110.1 - 9.1e-12 44.3 9.9 9.1e-12 44.3 9.9 1.4 1 1 0 1 1 1 1 Trehalose receptor UPF0242 PF06785.11 OWF40110.1 - 0.081 13.0 0.2 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pex24p PF06398.11 OWF40110.1 - 1.7 7.5 9.7 0.1 11.5 4.0 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin CfAFP PF05264.11 OWF40112.1 - 0.039 14.0 34.6 1.6 8.7 11.7 2.9 1 1 2 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) Alpha_E3_glycop PF01563.16 OWF40112.1 - 5.4 7.2 5.9 1.7e+02 2.4 0.4 4.5 3 1 1 4 4 4 0 Alphavirus E3 glycoprotein Pro_Al_protease PF02983.14 OWF40112.1 - 9.8 6.3 12.9 1.5e+02 2.5 0.1 5.3 2 1 3 5 5 5 0 Alpha-lytic protease prodomain IFT57 PF10498.9 OWF40113.1 - 8.6e-24 84.2 2.8 0.75 8.7 0.0 9.7 1 1 5 8 8 8 8 Intra-flagellar transport protein 57 Bromo_TP PF07524.13 OWF40113.1 - 7.7e-09 35.4 54.8 60 3.8 0.2 19.3 1 1 40 41 41 41 29 Bromodomain associated LRR_9 PF14580.6 OWF40114.1 - 1.8e-16 60.1 0.6 2.6e-16 59.6 0.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF40114.1 - 1.1e-11 44.7 15.5 7.3e-10 38.9 3.5 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF40114.1 - 3.9e-11 42.6 23.0 5.1e-08 32.6 4.2 3.2 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OWF40114.1 - 0.001 18.9 9.8 0.26 11.4 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat SAPS PF04499.15 OWF40114.1 - 1.4 7.6 10.1 1.5 7.6 10.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EF-hand_10 PF14788.6 OWF40115.1 - 0.035 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 EF hand Cornifin PF02389.15 OWF40116.1 - 8.7e-14 51.9 30.9 0.0064 16.7 0.3 8.2 1 1 7 8 8 8 8 Cornifin (SPRR) family SseC PF04888.12 OWF40116.1 - 0.12 12.0 77.2 1.9e+02 1.4 13.4 8.9 1 1 3 4 4 4 0 Secretion system effector C (SseC) like family 7tm_1 PF00001.21 OWF40117.1 - 3.1e-60 203.7 19.4 4.1e-60 203.3 19.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF40117.1 - 2.2e-14 53.5 21.1 2.2e-14 53.5 21.1 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF40117.1 - 1.2e-12 48.0 19.9 1.2e-12 48.0 19.9 2.5 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF40117.1 - 6.7e-08 32.2 24.1 2.9e-07 30.1 24.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 OWF40117.1 - 0.0021 17.9 17.3 0.0027 17.5 17.3 1.1 1 0 0 1 1 1 1 Olfactory receptor Methyltransf_21 PF05050.12 OWF40118.1 - 3.3e-11 43.5 0.0 5.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 OWF40118.1 - 9.6e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 OWF40118.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 5_nucleotid_C PF02872.18 OWF40118.1 - 0.022 15.0 0.0 0.076 13.2 0.0 1.8 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain PrmA PF06325.13 OWF40118.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sulfotransfer_1 PF00685.27 OWF40119.1 - 3.4e-12 46.4 1.6 6e-12 45.6 1.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF40119.1 - 2.2e-05 25.0 0.1 0.00078 19.9 0.1 2.9 1 1 0 1 1 1 1 Sulfotransferase family 7tm_1 PF00001.21 OWF40120.1 - 3.1e-28 98.8 23.1 4e-28 98.5 23.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF40120.1 - 2.6e-09 37.1 18.7 2.6e-09 37.1 18.7 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF40120.1 - 3.6e-06 26.6 24.8 6.5e-06 25.7 24.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 OWF40120.1 - 0.00034 20.2 17.0 0.00034 20.2 17.0 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 OWF40121.1 - 4.6e-27 95.0 20.6 5.8e-27 94.7 20.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF40121.1 - 6.8e-08 32.5 22.2 7.8e-08 32.3 20.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF40121.1 - 2.5e-05 23.8 24.8 4.1e-05 23.1 24.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 OWF40121.1 - 0.0001 21.9 13.1 0.0001 21.9 13.1 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Phage_holin_3_7 PF05449.11 OWF40121.1 - 0.017 15.1 0.7 0.017 15.1 0.7 3.4 4 1 0 4 4 4 0 Putative 3TM holin, Phage_holin_3 SrfB PF07520.11 OWF40121.1 - 0.12 10.2 0.5 0.17 9.8 0.5 1.1 1 0 0 1 1 1 0 Virulence factor SrfB DUF5305 PF17231.2 OWF40121.1 - 0.49 9.8 2.2 0.6 9.5 0.0 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5305) Spo7 PF03907.13 OWF40121.1 - 3.5 7.1 6.3 0.52 9.8 0.9 2.1 2 0 0 2 2 2 0 Spo7-like protein MFS_1 PF07690.16 OWF40122.1 - 3.1e-24 85.5 32.5 3.2e-24 85.5 31.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily 4HB_MCP_1 PF12729.7 OWF40122.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction fn3 PF00041.21 OWF40124.1 - 3e-164 533.8 46.9 6.2e-18 64.9 1.0 13.6 13 0 0 13 13 13 13 Fibronectin type III domain Ig_3 PF13927.6 OWF40124.1 - 6.7e-61 202.9 8.5 1.1e-13 51.6 0.0 7.8 7 0 0 7 7 7 5 Immunoglobulin domain I-set PF07679.16 OWF40124.1 - 3.3e-56 187.3 0.2 2.6e-14 53.0 0.0 8.1 8 0 0 8 8 7 5 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF40124.1 - 1.9e-37 127.4 9.7 2.3e-10 40.7 0.1 7.3 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.25 OWF40124.1 - 6.1e-26 90.4 4.0 2.5e-06 27.6 0.0 6.5 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.17 OWF40124.1 - 7.6e-24 84.0 6.8 0.00084 19.5 0.1 8.5 6 2 1 7 7 7 4 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 OWF40124.1 - 3.9e-18 65.8 29.9 0.0069 16.9 0.2 12.1 12 1 0 12 12 11 6 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF40124.1 - 7.6e-12 45.5 0.1 1.3 9.4 0.0 8.3 10 0 0 10 10 10 2 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 OWF40124.1 - 3.3e-09 36.2 0.0 0.13 11.9 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin domain Ig_4 PF16680.5 OWF40124.1 - 1.6e-07 31.5 0.5 0.0077 16.5 0.0 5.2 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 OWF40124.1 - 1.8e-07 31.5 0.4 0.026 14.9 0.0 4.9 5 1 0 5 5 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 OWF40124.1 - 3.6e-06 26.9 2.6 0.12 12.4 0.0 5.2 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF40124.1 - 3.5e-05 23.8 0.3 12 6.0 0.0 5.0 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain DUF2369 PF10179.9 OWF40124.1 - 8.9e-05 22.8 1.3 20 5.7 0.0 6.8 8 0 0 8 8 8 0 Uncharacterised conserved protein (DUF2369) Receptor_2B4 PF11465.8 OWF40124.1 - 0.0063 16.7 4.9 1.8 8.8 0.0 5.3 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 PhoD_N PF16655.5 OWF40124.1 - 0.079 13.5 0.0 2.4 8.8 0.0 3.2 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain ASH PF15780.5 OWF40124.1 - 0.44 10.8 3.0 5.4 7.3 0.1 3.6 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Pkinase PF00069.25 OWF40125.1 - 5.4e-49 166.9 0.0 6.9e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40125.1 - 6.8e-32 110.8 0.0 9.1e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF40125.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SRPRB PF09439.10 OWF40125.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Kdo PF06293.14 OWF40125.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF40125.1 - 0.18 11.7 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CPG4 PF15481.6 OWF40126.1 - 0.094 13.4 1.0 0.17 12.5 1.0 1.5 1 1 0 1 1 1 0 Chondroitin proteoglycan 4 CPG4 PF15481.6 OWF40127.1 - 0.091 13.4 0.8 0.58 10.8 0.1 2.2 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 HRM PF02793.22 OWF40127.1 - 0.18 12.1 3.1 0.8 10.0 0.1 2.8 3 1 0 3 3 3 0 Hormone receptor domain Ish1 PF10281.9 OWF40128.1 - 0.021 15.1 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein L_HMGIC_fpl PF10242.9 OWF40129.1 - 0.00014 22.1 2.5 0.00017 21.9 2.5 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Comm PF15957.5 OWF40129.1 - 0.02 15.2 1.0 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 Commissureless DUF2721 PF11026.8 OWF40129.1 - 0.043 13.7 0.6 0.061 13.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Phage_holin_3_6 PF07332.11 OWF40129.1 - 0.067 13.2 0.2 0.091 12.8 0.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3040 PF11239.8 OWF40129.1 - 5 7.5 8.8 36 4.7 8.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) GRAM PF02893.20 OWF40130.1 - 6.3e-12 45.4 0.0 9e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 OWF40130.1 - 0.0024 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Chromosome_seg PF13889.6 OWF40130.1 - 0.045 13.9 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation during meiosis bPH_3 PF14470.6 OWF40130.1 - 0.13 12.6 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain Pkinase PF00069.25 OWF40131.1 - 3.8e-29 101.9 0.0 4.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40131.1 - 1.7e-17 63.6 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF40131.1 - 4.3e-09 35.7 0.1 6.1e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OWF40131.1 - 0.00043 20.3 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OWF40131.1 - 0.028 13.4 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OWF40131.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family I-set PF07679.16 OWF40132.1 - 2.4e-20 72.4 0.1 6.6e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF40132.1 - 5.5e-17 62.1 1.5 1.3e-09 38.5 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF40132.1 - 3.3e-13 49.8 1.2 1.5e-07 31.6 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 OWF40132.1 - 1.1e-11 44.7 0.7 9.7e-06 25.7 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF40132.1 - 1e-08 35.3 0.5 0.00037 20.6 0.1 2.8 2 1 1 3 3 3 2 Immunoglobulin V-set domain Herpes_gE PF02480.16 OWF40132.1 - 0.00021 20.2 0.2 0.0013 17.6 0.1 1.9 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 OWF40132.1 - 0.00031 20.7 0.1 0.027 14.5 0.0 2.4 2 0 0 2 2 2 1 C17orf99 Ig domain Ig_6 PF18452.1 OWF40132.1 - 0.0033 17.0 2.5 0.62 9.7 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 OWF40132.1 - 0.0041 17.2 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Nucleos_tra2_C PF07662.13 OWF40132.1 - 0.023 14.5 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus Cu2_monooxygen PF01082.20 OWF40133.1 - 3e-79 263.7 0.1 1.1e-38 132.4 0.0 2.6 2 0 0 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF40133.1 - 7.3e-66 220.5 0.0 1.9e-42 144.4 0.0 2.4 2 0 0 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 OWF40133.1 - 6.9e-56 187.8 5.7 6.4e-28 97.5 0.6 2.5 2 0 0 2 2 2 2 DOMON domain BA14K PF07886.11 OWF40133.1 - 0.94 9.4 4.6 11 5.9 0.4 2.7 2 0 0 2 2 2 0 BA14K-like protein I-set PF07679.16 OWF40134.1 - 1.3e-23 82.9 0.1 1.7e-09 37.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF40134.1 - 9.6e-22 77.4 1.5 2e-10 41.1 0.2 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF40134.1 - 3.4e-15 56.2 2.6 3.8e-07 30.3 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 OWF40134.1 - 5.7e-13 48.8 1.4 2.9e-05 24.2 0.1 3.6 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 OWF40134.1 - 2.5e-12 47.0 1.6 0.00047 20.3 0.1 3.9 3 1 1 4 4 4 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF40134.1 - 0.00029 20.8 0.0 7.6 6.7 0.0 3.4 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF40134.1 - 0.00032 20.7 1.0 0.036 14.1 0.0 3.2 4 0 0 4 4 4 1 C17orf99 Ig domain Ig_6 PF18452.1 OWF40134.1 - 0.0022 17.5 3.8 0.65 9.6 0.0 4.1 5 0 0 5 5 5 2 Immunoglobulin domain Cu2_monoox_C PF03712.15 OWF40135.1 - 1.3e-41 141.8 0.0 2.8e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF40135.1 - 2.8e-38 131.1 0.2 5.2e-38 130.2 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 OWF40135.1 - 1e-28 100.0 0.5 3.2e-28 98.4 0.5 1.8 2 0 0 2 2 2 1 DOMON domain Cu2_monooxygen PF01082.20 OWF40136.1 - 4.5e-38 130.4 0.0 9.3e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF40136.1 - 4.4e-31 107.5 0.3 1e-14 54.3 0.0 2.4 1 1 1 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 OWF40136.1 - 6.5e-28 97.5 0.6 1.1e-27 96.7 0.6 1.4 1 0 0 1 1 1 1 DOMON domain GST_N PF02798.20 OWF40138.1 - 7.8e-14 51.8 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF40138.1 - 1.9e-13 50.6 0.0 3.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF40138.1 - 4e-13 49.4 0.2 8.3e-13 48.4 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF40138.1 - 3.4e-12 46.4 0.1 7.3e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF40138.1 - 2.3e-11 43.8 0.0 4.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF40138.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF40138.1 - 0.0014 19.3 0.0 0.0026 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 OWF40138.1 - 0.0036 17.9 0.0 0.093 13.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain CK2S PF15011.6 OWF40138.1 - 0.068 13.1 0.1 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Casein Kinase 2 substrate GST_C_6 PF17171.4 OWF40138.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4744 PF15918.5 OWF40139.1 - 6.3e-06 27.0 1.2 0.4 11.5 0.3 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4744) bPH_6 PF10756.9 OWF40139.1 - 0.00045 20.2 0.7 46 4.2 0.0 4.6 1 1 5 6 6 6 0 Bacterial PH domain CEL_III_C PF18054.1 OWF40139.1 - 2.5 8.1 15.2 4.2 7.4 5.8 2.1 1 1 1 2 2 2 0 CEL-III C-terminal Prophage_tail PF06605.11 OWF40139.1 - 5.3 6.2 16.7 1.8e+04 -7.1 16.7 4.2 1 1 0 1 1 1 0 Prophage endopeptidase tail GST_C PF00043.25 OWF40141.1 - 7.7e-13 48.5 0.1 1.1e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF40141.1 - 5.9e-12 45.8 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF40141.1 - 2e-11 43.9 0.0 3.7e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF40141.1 - 1.7e-09 37.8 0.0 3.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF40141.1 - 2e-09 37.6 0.0 3.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF40141.1 - 2e-08 34.1 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OWF40141.1 - 0.0018 18.9 0.0 0.024 15.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OWF40141.1 - 0.027 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain cwf21 PF08312.12 OWF40141.1 - 0.027 14.6 0.4 0.07 13.3 0.4 1.6 1 0 0 1 1 1 0 cwf21 domain ZapB PF06005.12 OWF40141.1 - 4 8.0 7.1 14 6.3 7.1 1.8 1 1 0 1 1 1 0 Cell division protein ZapB GST_N_3 PF13417.6 OWF40142.1 - 2.2e-12 47.2 0.0 2.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF40142.1 - 1.8e-11 44.2 0.0 2.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF40142.1 - 3.2e-11 43.4 0.0 4.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF40142.1 - 0.053 14.3 0.0 0.064 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain IRS PF02174.17 OWF40143.1 - 5.8e-21 74.3 0.0 1.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Muted PF14942.6 OWF40144.1 - 5.8e-38 130.5 10.8 6.6e-38 130.3 10.8 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein NDUFB10 PF10249.9 OWF40144.1 - 0.012 16.2 1.1 0.018 15.5 1.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 FUSC-like PF12805.7 OWF40144.1 - 0.092 11.8 0.6 0.13 11.3 0.3 1.4 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS Exonuc_VII_L PF02601.15 OWF40144.1 - 0.14 11.7 4.4 0.18 11.4 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 OWF40144.1 - 0.36 9.4 6.3 0.28 9.7 4.5 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF327 PF03885.13 OWF40144.1 - 0.5 10.3 6.4 0.15 12.0 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF327) CC2-LZ PF16516.5 OWF40144.1 - 0.89 10.0 10.6 4.5 7.7 0.4 3.1 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DASH_Duo1 PF08651.10 OWF40144.1 - 3.1 7.6 7.4 23 4.8 0.1 3.2 2 1 1 3 3 3 0 DASH complex subunit Duo1 XhlA PF10779.9 OWF40144.1 - 3.7 7.8 11.2 8.5 6.7 1.5 3.2 2 1 2 4 4 4 0 Haemolysin XhlA COesterase PF00135.28 OWF40145.1 - 8.3e-139 463.7 0.0 9.4e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF40145.1 - 6.3e-09 36.0 0.5 6.1e-08 32.8 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OWF40146.1 - 2.9e-131 438.8 0.0 3.4e-131 438.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF40146.1 - 4.6e-07 29.9 0.7 3e-06 27.2 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF40146.1 - 0.043 13.3 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OWF40146.1 - 0.075 13.6 0.7 0.14 12.8 0.2 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PUF PF00806.19 OWF40147.1 - 6.4e-70 227.1 12.5 2.7e-08 33.0 0.5 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF445 PF04286.12 OWF40147.1 - 0.044 13.6 1.6 0.37 10.6 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) sCache_2 PF17200.4 OWF40147.1 - 0.087 12.7 0.1 47 3.8 0.0 3.8 4 0 0 4 4 4 0 Single Cache domain 2 CPL PF08144.11 OWF40147.1 - 0.15 12.4 2.1 12 6.3 0.3 3.8 1 1 3 4 4 4 0 CPL (NUC119) domain Rota_NS6 PF04866.12 OWF40147.1 - 2.6 8.3 4.8 20 5.5 0.3 2.6 2 0 0 2 2 2 0 Rotavirus non-structural protein 6 Clathrin_lg_ch PF01086.17 OWF40148.1 - 6.3e-57 193.3 14.5 7.5e-57 193.0 14.5 1.1 1 0 0 1 1 1 1 Clathrin light chain LRR_8 PF13855.6 OWF40149.1 - 7.6e-12 44.8 10.7 4.2e-08 32.8 0.1 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OWF40149.1 - 1.9e-11 44.0 18.4 0.0053 17.1 0.1 4.9 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF40149.1 - 1.8e-09 37.4 0.3 0.028 13.9 0.0 3.4 2 1 1 3 3 3 3 Leucine-rich repeat MBOAT PF03062.19 OWF40150.1 - 3.6e-28 98.9 5.2 3.6e-28 98.9 5.2 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family F-box-like PF12937.7 OWF40151.1 - 6.2e-05 22.8 0.1 0.00014 21.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like IBR PF01485.21 OWF40151.1 - 7.7e-05 22.8 5.5 7.7e-05 22.8 5.5 2.0 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain F-box PF00646.33 OWF40151.1 - 0.00011 22.0 0.1 0.00033 20.5 0.0 1.8 1 1 0 1 1 1 1 F-box domain tRNA_int_endo PF01974.17 OWF40152.1 - 3.8e-20 71.7 0.0 6.8e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Lge1 PF11488.8 OWF40152.1 - 2.4 8.4 10.3 2.3 8.4 2.2 2.6 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF5401 PF17380.2 OWF40152.1 - 4.6 5.2 12.2 5.9 4.8 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MCM PF00493.23 OWF40153.1 - 4.8e-95 316.9 0.0 7.9e-95 316.2 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OWF40153.1 - 3.1e-33 114.3 0.0 5.6e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OWF40153.1 - 4.3e-22 78.3 1.8 1.2e-21 76.9 1.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OWF40153.1 - 1.4e-10 41.6 0.3 5.1e-10 39.9 0.3 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OWF40153.1 - 1.2e-07 31.4 0.0 5.7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF40153.1 - 0.0013 18.8 0.0 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OWF40153.1 - 0.0014 18.5 0.0 0.0044 16.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OWF40153.1 - 0.063 13.0 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Phtf-FEM1B_bdg PF12129.8 OWF40154.1 - 6.3e-52 175.5 5.1 2e-51 173.9 5.1 1.9 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Cadherin_C_2 PF16492.5 OWF40154.1 - 0.025 15.3 0.5 0.36 11.6 0.1 2.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Glyco_transf_7N PF13733.6 OWF40155.1 - 3.2e-44 149.8 0.5 7.3e-44 148.7 0.1 1.8 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF40155.1 - 1.3e-20 72.9 0.1 3e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF40155.1 - 0.00071 19.1 0.4 0.013 15.0 0.0 2.1 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Brr6_like_C_C PF10104.9 OWF40156.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Peptidase_C2 PF00648.21 OWF40157.1 - 1.4e-82 277.1 0.6 2.2e-82 276.4 0.6 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.18 OWF40157.1 - 1.3e-08 34.0 39.2 0.0064 15.8 1.8 5.1 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Amastin PF07344.11 OWF40158.1 - 0.0004 20.2 6.4 0.0011 18.8 5.8 2.0 1 1 0 1 1 1 1 Amastin surface glycoprotein L_HMGIC_fpl PF10242.9 OWF40158.1 - 0.0026 18.0 3.4 0.0067 16.7 3.4 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 OWF40158.1 - 0.0067 16.3 10.0 0.02 14.8 9.8 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 OWF40158.1 - 0.041 13.8 8.8 0.019 14.9 5.9 1.9 1 1 1 2 2 2 0 Tight junction protein, Claudin-like EMP70 PF02990.16 OWF40158.1 - 0.11 11.1 4.1 0.14 10.8 4.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Claudin_2 PF13903.6 OWF40158.1 - 0.14 11.9 19.7 1.3 8.8 12.5 3.1 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction PRA1 PF03208.19 OWF40158.1 - 3.3 7.3 9.2 0.7 9.5 5.9 1.5 2 0 0 2 2 2 0 PRA1 family protein Phage_holin_2_1 PF04971.12 OWF40158.1 - 6.7 6.8 8.0 1.4 8.9 0.2 2.7 3 0 0 3 3 3 0 Bacteriophage P21 holin S MARVEL PF01284.23 OWF40158.1 - 9 6.3 13.8 13 5.8 8.3 2.8 1 1 1 2 2 2 0 Membrane-associating domain Big_10 PF17964.1 OWF40159.1 - 0.16 12.0 5.6 10 6.1 0.4 3.1 1 1 2 3 3 3 0 Bacterial Ig domain PqqA PF08042.11 OWF40160.1 - 0.0018 18.2 199.3 0.19 11.8 0.6 27.9 24 6 6 30 30 30 16 PqqA family Xol-1_GHMP-like PF09109.10 OWF40160.1 - 0.067 13.1 18.1 3.5 7.5 1.4 4.5 1 1 5 6 6 6 0 Switch protein XOL-1, GHMP-like Big_10 PF17964.1 OWF40160.1 - 2.1 8.3 27.8 1.2 9.1 0.9 6.4 1 1 4 7 7 7 0 Bacterial Ig domain Sulfotransfer_1 PF00685.27 OWF40162.1 - 2.4e-12 46.9 0.7 2.4e-12 46.9 0.7 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF40162.1 - 4.6e-09 37.0 0.2 2.7e-08 34.5 0.0 2.4 2 1 0 2 2 2 1 Sulfotransferase family Reo_sigmaC PF04582.12 OWF40162.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain Homeodomain PF00046.29 OWF40163.1 - 8.8e-21 73.5 4.2 1.8e-20 72.5 4.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF40163.1 - 0.0095 15.8 0.1 0.026 14.4 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 OWF40163.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF4813 PF16072.5 OWF40164.1 - 0.0093 15.7 0.1 9.8 5.8 0.0 2.7 1 1 2 3 3 3 3 Domain of unknown function (DUF4813) IKKbetaNEMObind PF12179.8 OWF40164.1 - 0.018 15.1 8.4 68 3.6 0.2 5.9 1 1 7 8 8 8 0 I-kappa-kinase-beta NEMO binding domain Utp12 PF04003.12 OWF40164.1 - 0.11 12.9 2.7 18 5.7 0.3 2.9 1 1 2 3 3 3 0 Dip2/Utp12 Family DUF1729 PF08354.10 OWF40164.1 - 0.15 10.9 16.0 2.8 6.8 2.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) UPF0020 PF01170.18 OWF40164.1 - 0.32 10.6 5.5 7.4 6.2 0.5 2.4 1 1 0 2 2 2 0 Putative RNA methylase family UPF0020 MBOAT_2 PF13813.6 OWF40164.1 - 0.78 10.1 11.0 59 4.0 0.2 3.8 1 1 1 2 2 2 0 Membrane bound O-acyl transferase family IU_nuc_hydro PF01156.19 OWF40166.1 - 1.6e-73 247.9 0.0 1.9e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1687 PF07955.11 OWF40166.1 - 0.13 12.7 0.1 0.38 11.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) IU_nuc_hydro PF01156.19 OWF40167.1 - 6.3e-20 71.9 5.6 2.7e-19 69.9 1.8 2.0 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase PhyH PF05721.13 OWF40168.1 - 5.6e-27 95.4 0.0 7.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OWF40168.1 - 0.026 13.3 0.1 0.22 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) PhyH PF05721.13 OWF40169.1 - 4.9e-21 76.0 0.0 6.3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TatD_DNase PF01026.21 OWF40170.1 - 1.3e-29 103.4 0.0 1.7e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase EF-hand_7 PF13499.6 OWF40171.1 - 3.7e-14 52.9 0.1 2e-06 28.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF40171.1 - 2.2e-11 42.7 0.2 0.0074 16.1 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 OWF40171.1 - 5.9e-06 26.5 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF40171.1 - 6.5e-06 25.3 0.0 0.72 9.5 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OWF40171.1 - 0.00063 19.5 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Roc PF08477.13 OWF40172.1 - 6.5e-11 42.5 0.0 9.9e-07 29.0 0.2 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF40172.1 - 9.3e-11 41.9 1.8 1.9e-10 40.9 1.8 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 OWF40172.1 - 0.021 14.4 2.8 1.2 8.7 0.1 3.5 4 0 0 4 4 4 0 Ras family AAA_22 PF13401.6 OWF40172.1 - 0.055 13.8 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sulfotransfer_3 PF13469.6 OWF40172.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family AAA_16 PF13191.6 OWF40172.1 - 0.16 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RhoGAP PF00620.27 OWF40173.1 - 2.5e-19 69.6 0.0 3.9e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Pkinase_fungal PF17667.1 OWF40173.1 - 0.028 13.2 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Dpy19 PF10034.9 OWF40174.1 - 6.7e-191 635.9 18.1 1.8e-150 502.2 9.7 2.0 2 0 0 2 2 2 2 Q-cell neuroblast polarisation DUF3844 PF12955.7 OWF40174.1 - 0.36 11.0 2.2 3.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) T-box PF00907.22 OWF40175.1 - 1.1e-75 253.9 0.5 1.6e-75 253.5 0.5 1.2 1 0 0 1 1 1 1 T-box IBN_N PF03810.19 OWF40176.1 - 2.1e-06 27.6 0.3 9.5e-06 25.4 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain 7tm_1 PF00001.21 OWF40178.1 - 8.2e-43 146.6 20.5 1.1e-42 146.2 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF40178.1 - 2.8e-07 30.6 19.4 4.5e-05 23.3 13.2 2.3 1 1 1 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF40178.1 - 0.00011 21.7 24.3 0.00014 21.3 24.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF40178.1 - 1.7 7.9 27.5 0.073 12.3 17.4 2.5 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw UPF0182 PF03699.13 OWF40178.1 - 3.5 5.6 12.8 4.7 5.2 12.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Git3 PF11710.8 OWF40178.1 - 4.3 7.1 15.3 0.048 13.4 7.2 1.8 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 Cpn60_TCP1 PF00118.24 OWF40179.1 - 4e-149 497.4 9.1 4.6e-149 497.2 9.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FUR PF01475.19 OWF40179.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Ferric uptake regulator family PrpR_N PF06506.11 OWF40179.1 - 0.02 14.4 0.4 0.21 11.1 0.1 2.6 2 0 0 2 2 2 0 Propionate catabolism activator Macoilin PF09726.9 OWF40180.1 - 7.8e-242 804.6 56.1 3.5e-143 478.7 13.0 2.0 1 1 1 2 2 2 2 Macoilin family KASH_CCD PF14662.6 OWF40180.1 - 0.0044 16.9 10.0 0.0044 16.9 10.0 3.1 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH Trimer_CC PF08954.11 OWF40180.1 - 0.056 13.0 0.0 0.19 11.3 0.0 1.9 1 0 0 1 1 1 0 Trimerisation motif DUF1664 PF07889.12 OWF40180.1 - 4.5 7.3 12.8 2.7 8.0 0.8 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) LANC_like PF05147.13 OWF40181.1 - 1.7e-46 158.4 0.0 1.5e-31 109.3 0.0 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 OWF40181.1 - 6.3e-05 22.6 0.1 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus DoxX_2 PF13564.6 OWF40182.1 - 1.6e-06 28.1 0.1 3.4e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 DoxX-like family DUF2178 PF09946.9 OWF40182.1 - 0.0093 16.1 0.4 0.88 9.8 0.1 2.5 2 1 0 2 2 2 1 Predicted membrane protein (DUF2178) OAD_gamma PF04277.13 OWF40182.1 - 0.017 15.7 0.2 0.017 15.7 0.2 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FxsA PF04186.13 OWF40182.1 - 0.096 12.8 2.0 0.13 12.4 0.7 2.0 1 1 1 2 2 2 0 FxsA cytoplasmic membrane protein IQ PF00612.27 OWF40183.1 - 5.1e-05 22.7 14.9 0.0026 17.4 0.4 3.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif FokI_N PF02981.15 OWF40183.1 - 0.057 13.6 0.2 0.098 12.8 0.2 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Carla_C4 PF01623.17 OWF40183.1 - 0.16 11.9 0.3 0.35 10.8 0.3 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Spond_N PF06468.13 OWF40184.1 - 8.9e-70 234.7 0.1 1.5e-69 234.0 0.1 1.3 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 OWF40184.1 - 1.5e-31 108.4 67.2 9.4e-11 41.8 12.0 6.6 6 1 1 7 7 7 4 Thrombospondin type 1 domain Kunitz_BPTI PF00014.23 OWF40184.1 - 1.7e-19 69.8 8.8 9.1e-19 67.4 8.8 2.4 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Reeler PF02014.16 OWF40184.1 - 2.8e-18 66.9 0.1 9.2e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 Reeler domain SNAD4 PF18750.1 OWF40184.1 - 3 8.0 12.9 3.6 7.8 0.4 3.9 4 0 0 4 4 4 0 Secreted Novel AID/APOBEC-like Deaminase 4 G2F PF07474.12 OWF40185.1 - 0.021 14.6 0.2 18 5.0 0.0 4.6 1 1 3 5 5 5 0 G2F domain UPF0180 PF03698.13 OWF40185.1 - 0.028 14.6 0.0 45 4.3 0.0 5.0 2 2 3 5 5 5 0 Uncharacterised protein family (UPF0180) Glyco_hydro_49N PF17433.2 OWF40185.1 - 0.14 11.8 0.0 29 4.2 0.0 3.8 4 1 2 6 6 6 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain Clat_adaptor_s PF01217.20 OWF40186.1 - 0.62 10.0 6.8 7.1 6.6 0.3 2.5 1 1 0 2 2 2 0 Clathrin adaptor complex small chain DUF1398 PF07166.11 OWF40186.1 - 0.65 10.1 15.3 2.7 8.1 1.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1398) FlbD PF06289.11 OWF40186.1 - 2.7 7.7 44.5 1.2 8.8 11.5 4.1 1 1 3 4 4 4 0 Flagellar and Swarming motility proteins NRDE-2 PF08424.10 OWF40187.1 - 4e-12 45.9 4.7 6e-09 35.5 0.9 2.9 2 1 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 OWF40187.1 - 5e-06 26.9 0.2 17 6.6 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF40187.1 - 0.0023 17.9 4.3 24 5.4 0.7 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF40187.1 - 0.035 14.6 8.0 28 5.3 0.2 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat ChAPs PF09295.10 OWF40187.1 - 0.056 12.4 1.4 0.07 12.1 0.1 1.7 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.14 OWF40187.1 - 0.081 12.9 1.7 17 5.3 0.0 3.0 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) TPR_7 PF13176.6 OWF40187.1 - 0.25 11.5 3.2 13 6.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF40187.1 - 2.3 7.5 4.4 0.66 9.3 0.1 2.1 3 0 0 3 3 3 0 MalT-like TPR region AHSP PF09236.10 OWF40189.1 - 8.6 6.9 13.3 0.37 11.3 2.8 3.5 2 2 1 3 3 3 0 Alpha-haemoglobin stabilising protein zf-C3HC4_3 PF13920.6 OWF40190.1 - 3e-15 55.8 11.4 4.7e-15 55.2 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF40190.1 - 3e-05 23.8 10.4 5.6e-05 22.9 10.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF40190.1 - 3.4e-05 24.1 13.2 6.1e-05 23.3 13.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF40190.1 - 3.7e-05 23.5 13.3 6.7e-05 22.6 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF40190.1 - 0.00019 21.3 12.4 0.00036 20.3 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF40190.1 - 0.0003 20.7 12.6 0.00055 19.8 12.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF1664 PF07889.12 OWF40190.1 - 0.18 11.9 1.6 0.31 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PLAC8 PF04749.17 OWF40192.1 - 2.7e-16 60.4 17.5 3.9e-16 59.8 17.5 1.3 1 0 0 1 1 1 1 PLAC8 family DUF2477 PF10631.9 OWF40192.1 - 2.1 9.0 16.8 6.8 7.4 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) Rhodanese PF00581.20 OWF40193.1 - 1.9e-11 44.4 0.0 3.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ATP_synt_H PF05493.13 OWF40194.1 - 1.2e-20 73.7 5.8 1.5e-20 73.4 5.8 1.2 1 0 0 1 1 1 1 ATP synthase subunit H Amino_oxidase PF01593.24 OWF40195.1 - 3.1e-15 56.4 0.1 8.4e-15 55.0 0.0 1.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF40195.1 - 3.1e-11 43.3 0.1 3e-09 37.0 0.1 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF40195.1 - 7.6e-09 35.6 3.7 4.6e-05 23.2 3.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OWF40195.1 - 5.4e-08 32.4 0.9 2.5e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OWF40195.1 - 1e-07 31.4 7.2 2.8e-05 23.4 3.5 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 OWF40195.1 - 9.6e-07 28.3 0.1 0.00021 20.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF40195.1 - 3.3e-06 26.7 0.8 1.5e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OWF40195.1 - 5.2e-06 25.9 0.3 8.7e-06 25.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OWF40195.1 - 4e-05 24.1 3.5 0.0078 16.7 1.7 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF40195.1 - 0.0016 17.5 4.6 0.031 13.3 0.9 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 OWF40195.1 - 0.0018 17.2 1.2 0.024 13.5 0.4 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OWF40195.1 - 0.011 14.4 3.7 0.012 14.4 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 OWF40195.1 - 0.012 14.7 7.1 0.17 10.9 1.7 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OWF40195.1 - 0.024 13.9 0.7 0.048 12.9 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 OWF40195.1 - 0.038 12.5 0.1 4.5 5.7 0.0 2.3 2 0 0 2 2 2 0 GDP dissociation inhibitor IlvN PF07991.12 OWF40195.1 - 0.15 11.6 0.4 0.94 9.0 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Mis12 PF05859.12 OWF40196.1 - 1.5e-24 86.6 0.3 3e-24 85.6 0.3 1.5 1 0 0 1 1 1 1 Mis12 protein NPV_P10 PF05531.12 OWF40196.1 - 0.003 18.0 11.1 0.018 15.5 2.7 3.4 2 2 1 3 3 3 1 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 OWF40196.1 - 0.019 15.3 1.6 0.044 14.1 0.5 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4972 PF16342.5 OWF40196.1 - 0.027 14.1 4.1 0.2 11.4 0.4 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4972) T3SSipB PF16535.5 OWF40196.1 - 0.041 14.4 6.0 0.21 12.1 3.9 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF4164 PF13747.6 OWF40196.1 - 0.064 13.5 0.9 24 5.3 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) KxDL PF10241.9 OWF40196.1 - 0.079 13.2 2.4 10 6.5 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein ZapB PF06005.12 OWF40196.1 - 0.11 12.9 6.5 0.18 12.3 2.3 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 OWF40196.1 - 2.5 8.0 6.2 1.3 8.9 1.2 2.5 1 1 1 2 2 2 0 Septum formation initiator Ag332 PF04671.12 OWF40197.1 - 0.15 12.1 3.8 70 3.5 0.0 4.6 5 0 0 5 5 5 0 Erythrocyte membrane-associated giant protein antigen 332 PH PF00169.29 OWF40199.1 - 5.5e-36 123.3 0.4 1.8e-21 76.6 0.2 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OWF40199.1 - 1e-12 48.4 2.9 2.7e-06 27.7 1.7 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 OWF40199.1 - 1.1e-10 41.7 2.6 4.1e-05 23.8 0.5 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 OWF40199.1 - 8.8e-09 35.4 1.6 1.2e-06 28.6 0.2 2.7 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 OWF40199.1 - 3.4e-05 24.2 0.7 0.21 12.0 0.0 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 OWF40199.1 - 0.00014 22.0 0.0 0.042 14.0 0.0 2.3 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.10 OWF40199.1 - 0.00048 20.4 0.3 3.6 8.0 0.1 3.4 2 2 1 3 3 3 1 Plant pleckstrin homology-like region Myosin_TH1 PF06017.13 OWF40199.1 - 0.00092 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding PH_6 PF15406.6 OWF40199.1 - 0.011 16.1 0.0 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 OWF40199.1 - 0.019 14.8 0.3 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3127 PF11325.8 OWF40199.1 - 0.1 12.8 0.0 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) DHC_N2 PF08393.13 OWF40200.1 - 0.029 13.5 0.4 0.044 12.9 0.4 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF2408 PF10303.9 OWF40200.1 - 1.5 9.4 5.1 2.4 8.7 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LRR_8 PF13855.6 OWF40201.1 - 1.5e-91 300.1 119.0 1.1e-14 53.9 6.2 11.3 4 4 7 11 11 11 11 Leucine rich repeat EGF PF00008.27 OWF40201.1 - 1.5e-35 121.1 135.9 2e-07 31.1 6.6 12.3 12 0 0 12 12 11 7 EGF-like domain LRR_4 PF12799.7 OWF40201.1 - 1.5e-33 114.3 97.9 0.00072 19.9 2.4 13.6 10 2 4 14 14 14 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF40201.1 - 3.1e-32 111.2 15.7 5.7e-08 32.8 0.0 6.3 5 1 1 6 6 6 5 BspA type Leucine rich repeat region (6 copies) Laminin_G_1 PF00054.23 OWF40201.1 - 5.7e-21 75.1 0.0 9.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 OWF40201.1 - 8.6e-19 68.4 0.1 1.5e-18 67.6 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain LRR_9 PF14580.6 OWF40201.1 - 1.9e-16 60.0 42.4 0.0011 18.5 0.1 6.8 4 3 2 6 6 6 6 Leucine-rich repeat LRRNT PF01462.18 OWF40201.1 - 7.3e-15 54.2 58.7 4.7e-06 26.1 4.8 8.6 8 0 0 8 8 8 4 Leucine rich repeat N-terminal domain hEGF PF12661.7 OWF40201.1 - 1.6e-14 53.9 119.3 5.9e-07 29.9 2.5 13.4 14 1 0 14 14 12 6 Human growth factor-like EGF LRRCT PF01463.24 OWF40201.1 - 1.4e-10 40.8 2.9 0.036 14.6 0.1 5.7 4 0 0 4 4 4 2 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 OWF40201.1 - 0.00042 20.5 68.3 2.6 8.9 0.2 16.9 20 0 0 20 20 16 4 Leucine Rich Repeat EGF_CA PF07645.15 OWF40201.1 - 0.0013 18.9 6.6 0.0013 18.9 6.6 10.6 8 1 3 11 11 8 4 Calcium-binding EGF domain EGF_2 PF07974.13 OWF40201.1 - 0.012 15.9 11.5 0.012 15.9 11.5 12.6 15 1 1 16 16 11 0 EGF-like domain UB2H PF14814.6 OWF40201.1 - 0.063 13.3 0.0 2.3 8.3 0.0 3.1 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain LRR_2 PF07723.13 OWF40201.1 - 0.16 12.7 2.6 80 4.1 0.0 5.3 4 0 0 4 4 4 0 Leucine Rich Repeat Ubiq-Cytc-red_N PF09165.10 OWF40202.1 - 0.34 11.8 43.3 44 5.0 0.8 12.6 2 2 5 8 8 8 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal DSPc PF00782.20 OWF40203.1 - 4.6e-42 143.0 0.0 8.1e-42 142.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 OWF40203.1 - 5.1e-08 33.4 0.0 3.5e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 OWF40203.1 - 8.5e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BACK PF07707.15 OWF40204.1 - 7.6e-06 26.0 2.1 5.1e-05 23.3 1.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF40204.1 - 0.002 18.4 0.4 0.04 14.2 0.0 2.9 1 1 2 3 3 3 1 BTB/POZ domain RRM_1 PF00076.22 OWF40205.1 - 2.3e-07 30.5 0.0 2.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF40205.1 - 0.0074 16.4 0.0 0.0083 16.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif Sugar_tr PF00083.24 OWF40207.1 - 1.8e-113 379.8 30.3 4.1e-86 289.6 20.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF40207.1 - 6.2e-34 117.5 34.0 6.7e-32 110.8 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OWF40207.1 - 2.7e-06 26.1 7.2 3.8e-06 25.6 3.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPMT PF05724.11 OWF40207.1 - 0.19 11.3 0.0 0.5 10.0 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) PTE PF02126.18 OWF40208.1 - 2.7e-90 302.8 0.0 3.1e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family SelA PF03841.13 OWF40208.1 - 0.17 10.9 0.1 0.42 9.6 0.1 1.6 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase IGF2_C PF08365.11 OWF40210.1 - 0.03 14.3 5.3 8.5 6.5 0.2 3.7 1 1 3 4 4 4 0 Insulin-like growth factor II E-peptide DUF5605 PF18310.1 OWF40210.1 - 0.079 12.9 0.3 0.41 10.6 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5605) Tetradecapep PF08187.11 OWF40210.1 - 1.2 9.3 4.3 81 3.6 0.0 4.0 4 0 0 4 4 4 0 Myoactive tetradecapeptides family Tetraspanin PF00335.20 OWF40211.1 - 1.2e-40 139.7 4.0 1.6e-40 139.3 4.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 OWF40211.1 - 0.02 15.1 0.6 3.6 7.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF3961 PF13106.6 OWF40211.1 - 0.18 11.5 0.6 0.36 10.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Herpes_IE2_3 PF03361.14 OWF40212.1 - 0.036 13.9 9.5 17 5.3 0.4 4.3 1 1 4 5 5 5 0 Herpes virus intermediate/early protein 2/3 E1_FCCH PF16190.5 OWF40212.1 - 0.055 13.7 1.0 19 5.5 1.0 3.6 1 1 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain PTS_EIIC PF02378.18 OWF40212.1 - 2.5 7.0 19.1 1.7 7.6 0.9 3.3 1 1 2 4 4 4 0 Phosphotransferase system, EIIC Imm72 PF15584.6 OWF40213.1 - 0.39 10.9 0.8 38 4.5 0.1 3.0 1 1 2 3 3 3 0 Immunity protein 72 DUF5551 PF17705.1 OWF40213.1 - 1.2 8.7 18.3 14 5.3 0.6 4.6 1 1 3 4 4 4 0 Family of unknown function (DUF5551) KH_1 PF00013.29 OWF40214.1 - 0.076 12.9 4.5 3.5 7.5 0.2 3.8 1 1 1 2 2 2 0 KH domain Imm72 PF15584.6 OWF40214.1 - 0.5 10.5 1.2 31 4.8 1.1 3.3 1 1 1 2 2 2 0 Immunity protein 72 DUF5551 PF17705.1 OWF40214.1 - 1.3 8.6 14.9 14 5.3 0.4 4.2 1 1 4 5 5 5 0 Family of unknown function (DUF5551) HR_lesion PF05514.11 OWF40214.1 - 2.4 8.3 17.5 14 5.8 0.7 4.2 1 1 2 3 3 3 0 HR-like lesion-inducing Cupin_1 PF00190.22 OWF40214.1 - 7.7 6.1 14.5 39 3.8 2.1 4.9 1 1 2 3 3 3 0 Cupin Neuralized PF07177.12 OWF40215.1 - 0.00085 19.4 4.4 19 5.2 1.1 6.2 1 1 1 2 2 2 2 Neuralized Cupin_1 PF00190.22 OWF40215.1 - 1.9 8.1 21.4 2 8.0 0.1 7.3 1 1 5 6 6 6 0 Cupin DUF4744 PF15918.5 OWF40216.1 - 0.00048 20.9 37.6 11 6.9 0.5 11.1 1 1 7 9 9 9 5 Domain of unknown function (DUF4744) YdiH PF15930.5 OWF40217.1 - 0.017 15.3 33.6 44 4.3 0.0 11.3 1 1 19 20 20 20 0 Domain of unknown function Tetraspanin PF00335.20 OWF40218.1 - 1.9e-45 155.4 3.4 2.3e-45 155.1 3.4 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2371 PF10177.9 OWF40218.1 - 7.4 6.8 0.0 7.4 6.8 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2371) Tna_leader PF08053.11 OWF40220.1 - 8.6 6.5 11.3 37 4.5 0.1 4.3 5 0 0 5 5 5 0 Tryptophanase operon leader peptide vATP-synt_E PF01991.18 OWF40221.1 - 1e-66 224.2 9.6 1.2e-66 224.0 9.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Cytochrome_cB PF11783.8 OWF40221.1 - 0.06 13.2 0.3 0.088 12.7 0.3 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial A2M_recep PF07677.14 OWF40221.1 - 0.073 13.8 0.6 0.22 12.2 0.3 2.0 2 0 0 2 2 2 0 A-macroglobulin receptor binding domain OmpH PF03938.14 OWF40221.1 - 0.5 10.7 15.3 1.1 9.6 15.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 OWF40221.1 - 1.5 8.1 8.9 6.2 6.1 7.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Bcl-2 PF00452.19 OWF40222.1 - 2.1e-10 41.1 0.0 4.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family YopE_N PF09020.10 OWF40222.1 - 0.0072 16.6 0.5 0.0072 16.6 0.5 2.1 2 0 0 2 2 2 1 YopE, N terminal KCNQ_channel PF03520.14 OWF40223.1 - 4.2e-27 95.2 4.2 1.4e-26 93.5 4.2 1.8 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 OWF40223.1 - 5.3e-26 91.3 16.7 7.9e-26 90.8 16.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF40223.1 - 2.6e-11 43.3 9.3 2.6e-11 43.3 9.3 2.6 2 0 0 2 2 2 1 Ion channel Sensor PF13796.6 OWF40223.1 - 0.036 14.1 2.7 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 Putative sensor Unstab_antitox PF09720.10 OWF40223.1 - 0.12 12.5 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative addiction module component Beta_helix_2 PF18835.1 OWF40224.1 - 7.1e-08 32.1 2.1 77 3.1 0.0 15.7 1 1 41 44 44 44 2 Beta helix repeat of Inulin fructotransferase GLTT PF01744.20 OWF40225.1 - 3.3e-09 36.2 47.0 0.003 17.3 4.8 5.3 1 1 5 7 7 7 7 GLTT repeat (6 copies) Viral_RdRp_C PF17501.2 OWF40225.1 - 0.51 10.8 21.4 1.7 9.1 5.5 3.1 1 1 1 2 2 2 0 Viral RNA-directed RNA polymerase DUF1968 PF09291.10 OWF40225.1 - 8.7 6.5 13.5 13 6.0 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1968) RVT_1 PF00078.27 OWF40226.1 - 0.022 14.3 0.1 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 OWF40227.1 - 0.0054 17.0 0.8 0.0054 17.0 0.8 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein PhyH PF05721.13 OWF40229.1 - 1.5e-16 61.3 0.0 3.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ank_4 PF13637.6 OWF40230.1 - 4.5e-16 59.0 0.1 9.8e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF40230.1 - 1.6e-15 57.0 0.3 1.4e-09 38.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF40230.1 - 3.9e-14 53.0 0.1 5.7e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF40230.1 - 3.4e-13 48.5 0.3 6.6e-06 26.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OWF40230.1 - 4.4e-13 49.0 1.0 2.4e-05 24.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat FAM177 PF14774.6 OWF40231.1 - 2e-38 131.4 0.0 2.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 FAM177 family DUF4944 PF16302.5 OWF40231.1 - 0.047 13.8 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) zf-C4 PF00105.18 OWF40232.1 - 1.3e-31 108.8 11.7 2.9e-31 107.7 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF40232.1 - 2.1e-19 70.0 0.5 2.1e-19 70.0 0.5 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF4003 PF13170.6 OWF40232.1 - 0.14 11.5 0.0 0.46 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Glycos_transf_2 PF00535.26 OWF40233.1 - 3.1e-25 88.9 0.0 7.1e-25 87.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF40233.1 - 3.6e-07 30.5 0.4 7.2e-07 29.5 0.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 OWF40233.1 - 2.2e-05 24.0 0.1 4.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PHD PF00628.29 OWF40233.1 - 0.00052 19.9 3.0 0.0013 18.6 3.0 1.7 1 0 0 1 1 1 1 PHD-finger Glyco_tranf_2_2 PF10111.9 OWF40233.1 - 0.0084 15.6 0.0 0.039 13.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OWF40233.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 HscB_4_cys PF18256.1 OWF40233.1 - 0.032 14.0 2.2 0.14 12.0 0.6 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-CW PF07496.15 OWF40233.1 - 1.5 8.9 7.8 4.7 7.3 7.8 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger Methyltransf_11 PF08241.12 OWF40234.1 - 2e-12 47.6 0.0 2.5e-11 44.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF40234.1 - 2.6e-12 47.3 0.0 5.5e-10 39.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF40234.1 - 2e-11 43.9 0.0 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OWF40234.1 - 6.3e-10 39.7 0.0 4.5e-09 37.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF40234.1 - 9.1e-10 38.6 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OWF40234.1 - 0.091 12.2 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_9 PF08003.11 OWF40234.1 - 0.15 11.0 0.0 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) HSP9_HSP12 PF04119.12 OWF40235.1 - 0.066 13.6 2.8 0.19 12.2 0.1 2.7 2 0 0 2 2 2 0 Heat shock protein 9/12 Pneumo_M2 PF07380.11 OWF40235.1 - 0.066 13.5 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Pneumovirus M2 protein HipN PF18253.1 OWF40235.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Pkinase_Tyr PF07714.17 OWF40236.1 - 6e-66 222.4 0.0 8.9e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF40236.1 - 1e-59 202.0 0.0 1.8e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 OWF40236.1 - 1.6e-10 40.4 0.0 2.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF40236.1 - 8.5e-10 38.4 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF40236.1 - 1.4e-07 31.0 0.1 3.4e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pkinase_fungal PF17667.1 OWF40236.1 - 0.0018 17.1 0.7 0.0031 16.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF3552 PF12072.8 OWF40236.1 - 0.054 12.9 10.9 0.098 12.1 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.14 OWF40236.1 - 0.56 10.6 6.3 1 9.7 6.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Img2 PF05046.14 OWF40237.1 - 3.4e-24 84.9 1.0 3.7e-24 84.8 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) DUF1699 PF08004.11 OWF40237.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Asparaginase PF00710.20 OWF40238.1 - 8.2e-63 211.4 0.0 1.7e-62 210.4 0.0 1.6 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OWF40238.1 - 3.2e-28 98.2 0.0 1.2e-27 96.3 0.0 2.0 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 OWF40238.1 - 1.7e-19 70.2 0.9 2e-12 47.5 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF40238.1 - 1.2e-13 50.9 0.5 1e-05 25.7 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF40238.1 - 1.5e-13 51.0 0.5 1.3e-05 25.6 0.0 4.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF40238.1 - 9.8e-12 44.8 8.1 1e-05 25.8 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OWF40238.1 - 4.3e-10 38.9 0.1 0.00087 19.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ependymin PF00811.18 OWF40239.1 - 3.5e-26 91.9 0.1 4.7e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Ependymin Glyco_hydro_39 PF01229.17 OWF40240.1 - 0.1 11.1 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Glyco_hydro_2 PF00703.21 OWF40240.1 - 2.7 8.7 5.4 1.4 9.6 0.0 2.8 3 0 0 3 3 3 0 Glycosyl hydrolases family 2 ANF_receptor PF01094.28 OWF40241.1 - 2.6e-182 605.7 4.1 4e-43 147.9 0.5 5.4 5 0 0 5 5 5 5 Receptor family ligand binding region 7tm_3 PF00003.22 OWF40241.1 - 2.2e-33 116.0 19.2 3.9e-33 115.1 19.2 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 OWF40241.1 - 6.4e-28 98.4 2.4 0.00017 21.4 0.0 5.5 5 0 0 5 5 5 5 Periplasmic binding protein Drf_FH1 PF06346.12 OWF40241.1 - 0.022 14.5 0.4 0.042 13.6 0.4 1.4 1 0 0 1 1 1 0 Formin Homology Region 1 Sorb PF02208.16 OWF40241.1 - 0.1 12.5 0.3 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Sorbin homologous domain Collagen PF01391.18 OWF40241.1 - 1.4 8.7 4.9 2.8 7.8 4.9 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) HEAT_2 PF13646.6 OWF40242.1 - 7.1e-13 48.8 2.5 3.6e-09 36.9 0.1 2.4 1 1 1 2 2 2 2 HEAT repeats TIR_2 PF13676.6 OWF40242.1 - 1.3e-12 48.4 0.0 2.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain HEAT PF02985.22 OWF40242.1 - 9.2e-09 34.8 0.7 0.059 13.7 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 OWF40242.1 - 1.3e-05 25.5 0.2 0.1 13.1 0.0 3.1 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 OWF40242.1 - 0.00062 19.9 0.9 0.0041 17.2 0.3 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cbl_N2 PF02761.14 OWF40242.1 - 0.0019 18.9 1.7 0.0047 17.6 0.7 2.1 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain Vac14_Fab1_bd PF12755.7 OWF40242.1 - 0.0036 17.9 0.1 0.28 11.8 0.0 2.8 2 1 1 3 3 2 1 Vacuolar 14 Fab1-binding region Vitellogenin_N PF01347.22 OWF40242.1 - 0.013 14.0 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region DUF2268 PF10026.9 OWF40242.1 - 0.063 12.8 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) CP12 PF02672.15 OWF40242.1 - 0.12 13.2 0.8 0.29 11.9 0.1 2.0 2 0 0 2 2 2 0 CP12 domain AF-4 PF05110.13 OWF40242.1 - 0.66 8.0 3.2 0.93 7.5 3.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein 7tm_1 PF00001.21 OWF40244.1 - 9.6e-47 159.5 23.2 1.2e-46 159.2 23.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF40244.1 - 1e-09 38.2 26.0 1.4e-09 37.8 26.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF40244.1 - 1.9e-06 27.8 18.0 3.2e-06 27.1 18.0 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF40244.1 - 1.3e-05 24.9 27.6 2.3e-05 24.1 27.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TMF_DNA_bd PF12329.8 OWF40245.1 - 0.014 15.3 1.5 0.022 14.8 1.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3158 PF11358.8 OWF40245.1 - 0.014 15.1 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) DUF3450 PF11932.8 OWF40245.1 - 0.056 12.7 1.4 0.089 12.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Bacillus_HBL PF05791.11 OWF40245.1 - 0.17 11.7 1.3 0.25 11.2 1.3 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) SlyX PF04102.12 OWF40245.1 - 0.76 10.4 4.8 1.5 9.5 4.8 1.5 1 0 0 1 1 1 0 SlyX C1q PF00386.21 OWF40246.1 - 4.9e-20 72.0 0.0 9.5e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 C1q domain DUF1664 PF07889.12 OWF40246.1 - 0.032 14.3 0.9 0.06 13.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 OWF40246.1 - 0.049 14.3 1.1 0.078 13.6 1.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA BclA_C PF18573.1 OWF40246.1 - 0.078 12.9 0.5 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 BclA C-terminal domain Noelin-1 PF12308.8 OWF40246.1 - 0.17 11.9 0.4 0.29 11.1 0.4 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein Herpes_MCP PF03122.14 OWF40246.1 - 0.17 9.3 0.5 0.26 8.7 0.5 1.2 1 0 0 1 1 1 0 Herpes virus major capsid protein 7tm_1 PF00001.21 OWF40247.1 - 8.4e-39 133.5 18.3 8.4e-39 133.5 18.3 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF40247.1 - 7.7e-06 25.5 17.0 7.7e-06 25.5 17.0 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF40247.1 - 8.5e-06 25.6 18.9 8.6e-06 25.6 17.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Prominin PF05478.11 OWF40247.1 - 0.019 13.0 1.0 0.032 12.2 1.0 1.3 1 0 0 1 1 1 0 Prominin DUF2975 PF11188.8 OWF40247.1 - 1 9.2 0.0 1 9.2 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) HEAT_2 PF13646.6 OWF40248.1 - 8.9e-20 70.9 4.0 1.3e-13 51.1 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats TIR_2 PF13676.6 OWF40248.1 - 9.6e-17 61.7 0.0 2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain HEAT PF02985.22 OWF40248.1 - 2.3e-07 30.5 2.7 1.3 9.4 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat TIR PF01582.20 OWF40248.1 - 0.0003 20.7 0.2 0.00072 19.4 0.2 1.7 1 1 0 1 1 1 1 TIR domain HEAT_PBS PF03130.16 OWF40248.1 - 0.0017 18.9 5.9 0.26 12.0 0.0 3.4 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat Cnd1 PF12717.7 OWF40248.1 - 0.0067 16.5 2.4 0.13 12.3 0.1 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OWF40248.1 - 0.014 15.9 1.9 44 4.7 0.1 3.6 4 0 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 OWF40248.1 - 0.021 14.8 0.7 1.2 9.3 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cbl_N2 PF02761.14 OWF40248.1 - 0.052 14.3 0.2 0.88 10.3 0.2 2.7 2 1 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain AAA_lid_3 PF17862.1 OWF40248.1 - 0.14 12.0 0.4 2.3 8.1 0.1 2.8 2 0 0 2 2 2 0 AAA+ lid domain PUD1_2 PF18457.1 OWF40249.1 - 4.9 7.1 36.6 12 5.9 0.3 8.0 1 1 7 9 9 9 0 Up-Regulated in long-lived daf-2 STG PF15809.5 OWF40250.1 - 1.4e-18 67.8 31.3 0.34 10.9 0.9 9.2 1 1 14 15 15 15 15 Simian taste bud-specific gene product family Octopine_DH PF02317.17 OWF40250.1 - 2.3e-07 31.0 0.2 15 5.6 0.1 7.4 1 1 2 3 3 3 3 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain VWA PF00092.28 OWF40251.1 - 1e-92 309.2 6.7 3.5e-39 134.9 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF40251.1 - 1.7e-27 96.1 9.8 1.8e-12 47.8 0.0 3.8 3 1 1 4 4 4 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF40251.1 - 7.5e-13 48.7 0.1 7.5e-06 26.0 0.0 3.3 3 1 0 3 3 3 2 von Willebrand factor type A domain AhpC-TSA_2 PF13911.6 OWF40251.1 - 0.17 12.0 0.0 3.7 7.7 0.0 2.8 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme Med3 PF11593.8 OWF40251.1 - 0.59 9.3 12.6 0.86 8.7 12.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.17 OWF40251.1 - 4 7.4 38.0 8.1 6.4 38.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 OWF40251.1 - 7.9 6.9 16.5 17 5.8 16.5 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Metallophos PF00149.28 OWF40252.1 - 1.1e-27 97.9 0.2 1.8e-27 97.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 OWF40252.1 - 6.2e-06 26.6 2.7 0.0034 17.8 0.4 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF40252.1 - 1.5e-05 24.5 1.2 0.0059 16.4 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF40252.1 - 4.5e-05 22.7 4.3 0.0019 17.6 0.3 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OWF40252.1 - 0.17 11.8 0.9 2 8.3 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 OWF40252.1 - 0.98 9.0 7.6 0.19 11.3 0.2 3.0 3 0 0 3 3 3 0 EF hand zf-HIT PF04438.16 OWF40253.1 - 1.4e-09 37.6 12.0 3.1e-09 36.5 12.0 1.6 1 0 0 1 1 1 1 HIT zinc finger GerD PF17898.1 OWF40253.1 - 0.055 13.4 0.6 0.17 11.8 0.1 1.9 1 1 1 2 2 2 0 Spore germination GerD central core domain zf-MYND PF01753.18 OWF40253.1 - 0.071 13.2 14.0 0.19 11.9 13.9 1.8 1 1 0 1 1 1 0 MYND finger TAXi_N PF14543.6 OWF40253.1 - 0.1 12.8 5.3 0.11 12.7 5.3 1.2 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal PolC_DP2 PF03833.13 OWF40253.1 - 0.67 7.7 7.0 0.68 7.7 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Glyco_hydro_2_C PF02836.17 OWF40254.1 - 5.6e-84 281.8 1.3 7.8e-84 281.3 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OWF40254.1 - 1.8e-19 70.2 0.2 4.6e-19 68.9 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OWF40254.1 - 2.8e-05 24.8 0.0 5.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_cc PF11790.8 OWF40254.1 - 0.018 14.6 0.3 0.031 13.8 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.13 OWF40254.1 - 0.046 12.7 0.2 0.075 12.0 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 DUF4434 PF14488.6 OWF40254.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) DUF2781 PF10914.8 OWF40255.1 - 5.9e-43 146.8 13.6 8.2e-43 146.3 13.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) NUDIX PF00293.28 OWF40256.1 - 7.9e-11 42.1 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain S8_pro-domain PF16470.5 OWF40256.1 - 0.12 13.1 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase S8 pro-domain DUF4573 PF15140.6 OWF40257.1 - 0.00019 21.3 5.5 0.00027 20.8 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Med12 PF09497.10 OWF40257.1 - 0.0055 17.0 15.1 15 5.9 2.1 5.8 1 1 4 5 5 5 3 Transcription mediator complex subunit Med12 PdxA PF04166.12 OWF40257.1 - 0.59 9.5 1.9 26 4.1 0.1 2.9 1 1 2 3 3 3 0 Pyridoxal phosphate biosynthetic protein PdxA Nup88 PF10168.9 OWF40258.1 - 4.6e-159 530.5 0.1 2.1e-148 495.3 0.0 2.0 1 1 1 2 2 2 2 Nuclear pore component Ac81 PF05820.11 OWF40258.1 - 0.038 13.6 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae AC81 Phage_TTP_12 PF16461.5 OWF40258.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP CUT PF02376.15 OWF40259.1 - 1e-75 249.9 0.1 6.4e-24 83.9 0.0 3.8 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 OWF40259.1 - 5.2e-15 55.0 0.3 5.2e-15 55.0 0.3 2.9 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 OWF40259.1 - 0.00051 19.9 0.0 0.0017 18.2 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain DUF2315 PF10231.9 OWF40259.1 - 0.0095 16.0 3.0 0.0095 16.0 3.0 2.7 2 0 0 2 2 2 1 Apoptogenic protein 1 Keratin_B2 PF01500.17 OWF40261.1 - 0.061 13.3 19.7 1.4 8.9 19.7 2.4 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Clathrin_propel PF01394.20 OWF40261.1 - 0.12 12.7 3.4 48 4.5 0.0 4.7 4 1 1 5 5 5 0 Clathrin propeller repeat Keratin_B2_2 PF13885.6 OWF40261.1 - 2.3 8.2 20.3 36 4.4 16.2 3.5 2 1 0 2 2 2 0 Keratin, high sulfur B2 protein SfsA_N PF17746.1 OWF40262.1 - 0.00031 20.8 3.7 18 5.6 0.2 6.3 2 1 5 7 7 7 1 SfsA N-terminal OB domain DUF3798 PF12683.7 OWF40262.1 - 0.026 13.9 1.2 17 4.7 0.3 3.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3798) GAGBD PF16828.5 OWF40262.1 - 0.033 14.3 0.3 0.84 9.7 0.1 2.5 2 1 1 3 3 3 0 GAG-binding domain on surface antigen Tcp10_C PF07202.13 OWF40262.1 - 0.28 11.1 9.4 6.2 6.7 0.3 3.6 1 1 2 3 3 3 0 T-complex protein 10 C-terminus RNA_pol_Rpb2_1 PF04563.15 OWF40262.1 - 5.8 6.4 7.5 9.9 5.6 0.8 2.5 1 1 2 3 3 3 0 RNA polymerase beta subunit Acyl_transf_3 PF01757.22 OWF40264.1 - 4.4e-23 81.9 45.1 8.5e-23 81.0 45.1 1.5 1 0 0 1 1 1 1 Acyltransferase family Oxysterol_BP PF01237.18 OWF40265.1 - 3.4e-138 460.5 2.5 3.4e-138 460.5 2.5 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein PH PF00169.29 OWF40265.1 - 2.8e-15 56.7 0.2 8.8e-15 55.1 0.2 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OWF40265.1 - 2.5e-11 43.7 0.5 5.8e-11 42.5 0.5 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 OWF40265.1 - 0.00018 21.8 0.0 0.00057 20.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OWF40265.1 - 0.00028 21.3 9.7 0.0038 17.6 6.1 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain DUF501 PF04417.12 OWF40265.1 - 0.017 15.0 0.7 0.048 13.5 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Exonuc_VII_S PF02609.16 OWF40265.1 - 0.021 14.9 2.2 1.5 8.9 0.9 2.9 2 0 0 2 2 2 0 Exonuclease VII small subunit Syntaxin-6_N PF09177.11 OWF40265.1 - 3.9 8.1 8.6 1.3 9.6 1.0 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal zf-B_box PF00643.24 OWF40266.1 - 1.9e-12 47.1 20.9 3.6e-06 27.0 7.9 2.8 2 0 0 2 2 2 2 B-box zinc finger Reg_prop PF07494.11 OWF40266.1 - 0.0051 16.9 0.1 1.5 9.3 0.0 3.2 3 0 0 3 3 2 1 Two component regulator propeller DUF1664 PF07889.12 OWF40266.1 - 0.0068 16.4 6.8 0.036 14.1 2.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Taxilin PF09728.9 OWF40266.1 - 0.011 15.0 6.9 0.42 9.7 0.8 2.5 2 1 1 3 3 3 0 Myosin-like coiled-coil protein SGL PF08450.12 OWF40266.1 - 0.013 15.1 0.2 7.3 6.1 0.0 3.1 2 1 2 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Uteroglobin PF01099.17 OWF40266.1 - 0.026 14.8 3.7 0.31 11.4 0.4 2.7 1 1 1 2 2 2 0 Uteroglobin family ECM11 PF15463.6 OWF40266.1 - 0.032 14.8 1.7 0.045 14.3 0.1 2.0 2 1 0 2 2 2 0 Extracellular mutant protein 11 V-SNARE PF05008.15 OWF40266.1 - 0.1 13.0 4.3 0.12 12.8 0.8 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Apolipoprotein PF01442.18 OWF40266.1 - 0.22 11.4 3.9 0.42 10.5 3.9 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain EAP30 PF04157.16 OWF40266.1 - 0.3 10.3 3.1 0.67 9.2 1.6 2.0 2 1 0 2 2 2 0 EAP30/Vps36 family Laminin_II PF06009.12 OWF40266.1 - 0.3 11.1 4.5 0.67 10.0 4.3 1.6 1 1 0 1 1 1 0 Laminin Domain II OmpH PF03938.14 OWF40266.1 - 0.44 10.9 7.0 0.44 10.9 2.0 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 OWF40266.1 - 0.69 9.5 5.8 3.6 7.1 0.5 2.4 1 1 1 2 2 2 0 fzo-like conserved region THOC7 PF05615.13 OWF40266.1 - 0.87 9.9 5.9 2.5 8.4 1.1 2.4 1 1 0 2 2 2 0 Tho complex subunit 7 Syntaxin-6_N PF09177.11 OWF40266.1 - 2.4 8.8 9.7 75 4.0 5.5 3.7 3 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF4200 PF13863.6 OWF40266.1 - 4.3 7.8 10.8 1.2 9.5 3.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Snapin_Pallidin PF14712.6 OWF40266.1 - 4.8 7.7 7.0 15 6.1 1.8 2.5 1 1 1 2 2 2 0 Snapin/Pallidin CdvA PF18822.1 OWF40266.1 - 4.8 7.0 9.1 14 5.6 0.8 2.5 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Casc1_N PF15927.5 OWF40266.1 - 7 6.3 8.2 3.8 7.1 0.5 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Copine PF07002.16 OWF40267.1 - 1.3e-62 211.1 0.0 1.8e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 OWF40267.1 - 9.4e-11 42.2 0.0 1.4e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 OWF40267.1 - 0.0041 17.4 0.0 0.017 15.4 0.0 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain HemY_N PF07219.13 OWF40267.1 - 0.027 14.7 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus DUF1748 PF08520.10 OWF40268.1 - 0.077 12.9 0.3 6.7 6.7 0.0 3.5 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1748) DUF5564 PF17719.1 OWF40268.1 - 0.11 12.7 0.4 14 5.9 0.1 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5564) RhaA PF06134.11 OWF40269.1 - 0.21 10.7 1.8 1.7 7.7 1.9 1.9 1 1 1 2 2 2 0 L-rhamnose isomerase (RhaA) AidB_N PF18158.1 OWF40269.1 - 0.33 10.9 6.3 1.9 8.4 0.4 3.3 1 1 3 4 4 4 0 Adaptive response protein AidB N-terminal domain B9-C2 PF07162.11 OWF40270.1 - 7.2e-47 159.7 0.0 1.3e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein CAP_N PF01213.19 OWF40271.1 - 0.023 14.2 3.0 0.031 13.8 0.7 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 OWF40271.1 - 0.44 10.6 3.9 1.1 9.4 3.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 YqfD PF06898.11 OWF40271.1 - 0.74 8.6 2.4 1.1 8.0 2.4 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD zf-C3HC4_3 PF13920.6 OWF40272.1 - 1.4e-07 31.3 6.3 2.3e-07 30.6 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF40272.1 - 3.5e-07 30.0 7.1 7.2e-07 29.0 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF40272.1 - 2.4e-06 27.8 7.9 5.5e-06 26.6 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF40272.1 - 2.5e-06 27.4 6.2 5.4e-06 26.3 2.9 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF40272.1 - 5.2e-06 26.3 6.0 1.4e-05 24.9 6.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF40272.1 - 6.1e-05 22.8 7.5 6.1e-05 22.8 7.5 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF40272.1 - 0.0039 17.3 6.9 0.0081 16.3 6.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF40272.1 - 0.0044 16.9 8.1 0.049 13.5 7.5 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OWF40272.1 - 0.18 11.7 2.4 0.4 10.6 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OWF40272.1 - 0.31 11.2 3.2 0.7 10.1 3.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 TerY_C PF15616.6 OWF40272.1 - 0.68 10.1 3.2 0.35 11.0 0.7 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-rbx1 PF12678.7 OWF40272.1 - 1.4 9.3 8.0 4.3 7.7 8.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 OWF40272.1 - 3.8 7.3 9.6 12 5.8 9.6 1.8 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 OWF40272.1 - 6.4 6.6 6.8 31 4.4 3.2 2.7 2 1 0 2 2 2 0 RING-like zinc finger FCH PF00611.23 OWF40273.1 - 6.8e-19 67.9 1.6 6.8e-19 67.9 1.6 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain CorA PF01544.18 OWF40273.1 - 0.028 13.7 2.4 0.06 12.7 2.0 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein C1-set PF07654.15 OWF40273.1 - 0.67 10.4 4.2 0.49 10.8 1.4 2.2 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Spore_III_AB PF09548.10 OWF40273.1 - 1.8 8.6 6.7 0.63 10.1 0.8 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4735 PF15882.5 OWF40274.1 - 1.1e-75 254.8 0.1 1.3e-75 254.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) Peptidase_M14 PF00246.24 OWF40275.1 - 5.6e-76 256.1 0.0 7.7e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 OWF40275.1 - 1.1e-09 38.4 0.1 1.8e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.14 OWF40275.1 - 0.0039 16.3 0.2 0.0076 15.4 0.2 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family CarbopepD_reg_2 PF13715.6 OWF40275.1 - 0.011 15.7 0.1 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Y_Y_Y PF07495.13 OWF40275.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PetN PF03742.14 OWF40275.1 - 0.59 10.1 4.0 1.4 8.9 4.0 1.6 1 0 0 1 1 1 0 PetN Pkinase PF00069.25 OWF40276.1 - 1.5e-55 188.4 0.0 1.8e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40276.1 - 1.4e-24 86.8 0.0 2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF40276.1 - 0.00013 21.1 0.0 0.00033 19.7 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF40276.1 - 0.055 13.4 0.0 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Orn_DAP_Arg_deC PF00278.22 OWF40277.1 - 0.082 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Integrin_alpha2 PF08441.12 OWF40277.1 - 0.26 10.1 0.9 0.43 9.4 0.9 1.2 1 0 0 1 1 1 0 Integrin alpha Pkinase PF00069.25 OWF40278.1 - 1.4e-61 208.2 0.0 1.4e-61 208.2 0.0 2.8 3 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40278.1 - 2.8e-43 148.1 0.0 2.8e-43 148.1 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 OWF40278.1 - 0.097 12.6 0.0 0.097 12.6 0.0 3.1 3 1 0 3 3 3 0 Phosphotransferase enzyme family Ion_trans PF00520.31 OWF40279.1 - 3e-32 111.8 24.5 4.1e-32 111.4 24.5 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF40279.1 - 5.4e-24 84.4 0.0 1.5e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF40279.1 - 1.3e-10 41.1 7.0 1.3e-10 41.1 7.0 2.2 2 0 0 2 2 2 1 Ion channel Nudix_hydro PF18290.1 OWF40280.1 - 7.8e-06 25.8 8.4 32 4.6 0.1 8.7 2 1 8 10 10 10 2 Nudix hydrolase domain GerD PF17898.1 OWF40280.1 - 0.0099 15.8 0.0 12 5.9 0.0 3.4 1 1 3 4 4 4 2 Spore germination GerD central core domain TrkA_N PF02254.18 OWF40280.1 - 2.9 8.2 8.2 18 5.6 0.2 3.7 1 1 2 3 3 3 0 TrkA-N domain Myotub-related PF06602.14 OWF40281.1 - 4.6e-132 440.2 0.5 1.5e-131 438.5 0.0 1.9 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain FYVE PF01363.21 OWF40281.1 - 2.6e-19 69.1 8.7 2.6e-19 69.1 8.7 3.2 3 0 0 3 3 3 1 FYVE zinc finger DSPc PF00782.20 OWF40281.1 - 0.014 15.2 0.0 0.069 13.0 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain FYVE_2 PF02318.16 OWF40281.1 - 0.016 15.4 4.9 0.1 12.8 4.9 2.4 1 0 0 1 1 1 0 FYVE-type zinc finger Y_phosphatase PF00102.27 OWF40281.1 - 0.043 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-RING_5 PF14634.6 OWF40281.1 - 5.3 7.1 16.2 6 6.9 13.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain C1q PF00386.21 OWF40282.1 - 6.7e-28 97.4 0.1 7.7e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF40282.1 - 0.017 15.1 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 BclA C-terminal domain C1q PF00386.21 OWF40283.1 - 5.3e-26 91.3 0.6 6.1e-26 91.1 0.6 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF40283.1 - 0.015 15.2 0.6 0.019 14.9 0.6 1.1 1 0 0 1 1 1 0 BclA C-terminal domain C1q PF00386.21 OWF40284.1 - 4.4e-25 88.3 0.1 6e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF40284.1 - 0.0039 17.1 0.3 0.0056 16.6 0.3 1.2 1 0 0 1 1 1 1 BclA C-terminal domain DMPK_coil PF08826.10 OWF40284.1 - 0.0044 17.1 3.6 0.0078 16.3 3.6 1.4 1 0 0 1 1 1 1 DMPK coiled coil domain like bZIP_1 PF00170.21 OWF40284.1 - 0.0049 16.9 3.3 0.13 12.3 1.0 2.2 1 1 1 2 2 2 2 bZIP transcription factor MAD PF05557.13 OWF40284.1 - 0.0085 14.5 1.5 0.012 14.1 1.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein CCDC92 PF14916.6 OWF40284.1 - 0.026 14.3 0.1 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Herpes_BLRF2 PF05812.12 OWF40284.1 - 0.029 14.5 3.5 0.12 12.5 0.6 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Fez1 PF06818.15 OWF40284.1 - 0.039 14.4 0.9 0.046 14.2 0.9 1.1 1 0 0 1 1 1 0 Fez1 Macoilin PF09726.9 OWF40284.1 - 0.071 11.7 1.4 0.095 11.2 1.4 1.1 1 0 0 1 1 1 0 Macoilin family fragilysinNterm PF16376.5 OWF40284.1 - 0.092 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of fragilysin FPP PF05911.11 OWF40284.1 - 0.14 10.3 4.6 0.16 10.1 4.6 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 OWF40284.1 - 0.32 10.3 1.0 0.41 9.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cnn_1N PF07989.11 OWF40284.1 - 0.32 11.2 2.7 0.56 10.4 2.7 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF724 PF05266.14 OWF40284.1 - 0.36 10.6 3.3 0.47 10.3 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 OWF40284.1 - 0.72 9.7 2.7 11 5.9 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4651 PF15513.6 OWF40285.1 - 4.7e-14 52.0 21.0 1.7 8.6 0.0 12.6 3 2 12 15 15 15 9 Domain of unknown function (DUF4651) Aim19 PF10315.9 OWF40285.1 - 0.00032 21.0 19.9 28 5.1 0.0 9.0 6 2 4 12 12 12 2 Altered inheritance of mitochondria protein 19 zf-BED PF02892.15 OWF40285.1 - 0.072 13.1 2.6 1.7e+02 2.4 0.0 4.8 4 1 1 5 5 5 0 BED zinc finger SNF PF00209.18 OWF40286.1 - 7.5e-224 744.2 29.7 3.7e-223 742.0 29.7 1.8 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family MOZART2 PF12926.7 OWF40287.1 - 2.9e-29 100.5 0.1 3.5e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DGCR6 PF07324.11 OWF40287.1 - 0.18 11.4 0.1 0.29 10.7 0.1 1.5 1 1 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein NIBRIN_BRCT_II PF16508.5 OWF40288.1 - 1.5e-24 86.6 0.0 5.4e-24 84.8 0.0 2.1 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein Nbs1_C PF08599.10 OWF40288.1 - 2.9e-23 81.8 0.6 2.9e-23 81.8 0.6 2.1 2 0 0 2 2 2 1 DNA damage repair protein Nbs1 FHA PF00498.26 OWF40288.1 - 6.1e-13 48.9 0.0 3.5e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 FHA domain RTT107_BRCT_5 PF16770.5 OWF40288.1 - 4.3e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 OWF40288.1 - 5.4e-05 23.4 1.2 0.0023 18.2 0.1 3.1 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PTCB-BRCT PF12738.7 OWF40288.1 - 0.013 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 OWF40288.1 - 0.025 15.0 0.0 0.21 12.0 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain TMEM214 PF10151.9 OWF40288.1 - 0.051 12.0 0.0 0.051 12.0 0.0 2.4 3 0 0 3 3 3 0 TMEM214, C-terminal, caspase 4 activator Metallophos PF00149.28 OWF40289.1 - 6.1e-13 49.7 0.0 7.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF40289.1 - 2.4e-06 27.8 0.0 2.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HEPN_DZIP3 PF18738.1 OWF40290.1 - 5e-31 107.4 2.5 5.5e-31 107.2 0.1 2.3 2 1 1 3 3 3 1 DZIP3/ hRUL138-like HEPN CARD PF00619.21 OWF40290.1 - 1.4e-08 34.6 2.1 3.8e-08 33.2 2.1 1.8 1 0 0 1 1 1 1 Caspase recruitment domain NACHT PF05729.12 OWF40290.1 - 2.3e-07 30.9 0.0 7.4e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 OWF40290.1 - 1.7e-05 24.5 1.8 2.3 8.5 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat CARD_2 PF16739.5 OWF40290.1 - 0.0056 16.6 0.5 0.016 15.2 0.5 1.8 1 0 0 1 1 1 1 Caspase recruitment domain AAA_16 PF13191.6 OWF40290.1 - 0.032 14.6 0.0 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain HSF_DNA-bind PF00447.17 OWF40290.1 - 0.055 14.1 0.5 0.14 12.8 0.5 1.7 1 0 0 1 1 1 0 HSF-type DNA-binding AAA_18 PF13238.6 OWF40290.1 - 0.085 13.4 0.0 4.1 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OWF40290.1 - 0.17 11.7 0.0 0.61 9.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MEIOC PF15189.6 OWF40290.1 - 0.9 9.1 4.2 0.73 9.4 0.5 2.5 3 0 0 3 3 3 0 Meiosis-specific coiled-coil domain-containing protein MEIOC Lectin_C PF00059.21 OWF40291.1 - 0.00015 22.5 0.1 0.00015 22.5 0.1 2.0 2 0 0 2 2 2 1 Lectin C-type domain Ldt_C PF17969.1 OWF40293.1 - 0.38 11.5 2.9 17 6.2 0.1 3.1 1 1 1 2 2 2 0 L,D-transpeptidase C-terminal domain MSSP PF03940.13 OWF40293.1 - 8.2 6.1 14.6 8.3e+03 -3.5 0.0 3.9 2 1 0 2 2 2 0 Male specific sperm protein Ras PF00071.22 OWF40294.1 - 2.3e-53 180.1 0.0 2.6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF40294.1 - 2e-19 70.0 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF40294.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 OWF40294.1 - 0.0048 17.1 0.1 0.0074 16.5 0.1 1.3 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial GTP_EFTU PF00009.27 OWF40294.1 - 0.013 15.1 0.2 0.075 12.6 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain UPF0113_N PF17833.1 OWF40295.1 - 5.3e-33 113.4 0.2 7.7e-33 112.9 0.2 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OWF40295.1 - 9.2e-24 83.5 0.0 1.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 OWF40295.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 PUA domain DUF2647 PF10839.8 OWF40295.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2647) CCDC23 PF15674.5 OWF40296.1 - 3.1e-15 55.9 14.4 3.1e-15 55.9 14.4 2.6 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 23 His_Phos_2 PF00328.22 OWF40297.1 - 1.3e-06 28.0 0.3 0.0091 15.4 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Neurensin PF14927.6 OWF40298.1 - 0.39 10.4 3.6 0.34 10.6 1.5 2.1 1 1 1 2 2 2 0 Neurensin DUF389 PF04087.14 OWF40298.1 - 1.9 8.5 8.1 1.8e+02 2.2 8.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF389) DUF3955 PF13127.6 OWF40298.1 - 7.7 6.4 18.4 4.3 7.2 0.5 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3955) MF_alpha_N PF05436.11 OWF40299.1 - 5.3e-06 26.2 0.0 15 5.6 0.0 5.9 2 1 5 7 7 7 2 Mating factor alpha precursor N-terminus zf-3CxxC_2 PF17180.4 OWF40299.1 - 0.0021 18.7 17.5 9.5 7.0 0.2 5.9 2 2 4 6 6 6 1 Zinc-binding domain Head_binding PF09008.10 OWF40299.1 - 0.02 15.2 9.9 31 4.9 0.0 6.4 5 2 2 7 7 7 0 Head binding DUF5433 PF17498.2 OWF40299.1 - 0.11 12.7 7.8 10 6.4 0.1 4.8 3 2 1 5 5 5 0 Family of unknown function (DUF5433) Polyhedrin PF00738.18 OWF40299.1 - 0.13 11.5 3.5 10 5.4 0.1 3.7 1 1 4 5 5 5 0 Polyhedrin DUF3346 PF11826.8 OWF40299.1 - 2.3 7.9 10.0 26 4.5 0.1 4.8 1 1 4 6 6 6 0 Protein of unknown function (DUF3346) Cytochrom_c3_2 PF14537.6 OWF40299.1 - 3 8.4 23.9 5.5 7.5 3.3 3.8 1 1 2 3 3 3 0 Cytochrome c3 Guanylate_cyc PF00211.20 OWF40300.1 - 5.3e-59 198.9 0.0 1.2e-58 197.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 OWF40300.1 - 2.4e-24 87.1 0.0 3.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 OWF40300.1 - 0.0036 16.7 0.1 0.0067 15.9 0.1 1.4 1 0 0 1 1 1 1 Heme NO binding associated SNase PF00565.17 OWF40304.1 - 0.00017 22.0 0.0 0.00058 20.3 0.0 1.9 2 1 0 2 2 2 1 Staphylococcal nuclease homologue DUF5402 PF17393.2 OWF40304.1 - 0.04 13.9 0.1 0.085 12.8 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5402) EF-hand_7 PF13499.6 OWF40305.1 - 6.2e-18 65.0 2.0 5.9e-09 36.3 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF40305.1 - 2.8e-14 52.7 3.5 4.5e-08 32.8 0.4 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF40305.1 - 4.7e-14 50.8 6.6 2.6e-07 29.7 0.3 4.9 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF40305.1 - 2e-12 46.0 4.3 0.0069 16.2 0.1 4.5 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 OWF40305.1 - 7e-07 28.5 4.3 7.1e-05 22.1 0.3 3.8 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 OWF40305.1 - 0.0005 20.3 0.0 0.0041 17.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain TerB PF05099.13 OWF40305.1 - 0.0027 17.7 0.1 0.084 12.8 0.0 2.7 2 1 1 3 3 3 2 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 OWF40305.1 - 0.0086 16.4 0.0 2.8 8.3 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 OWF40305.1 - 0.013 15.3 0.4 1.1 9.1 0.1 2.2 1 1 0 2 2 2 0 SurA N-terminal domain YjbR PF04237.13 OWF40305.1 - 0.016 15.8 0.0 3.4 8.3 0.0 2.6 1 1 2 3 3 3 0 YjbR EF-hand_4 PF12763.7 OWF40305.1 - 0.016 15.1 0.3 0.12 12.3 0.1 2.2 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 OWF40305.1 - 0.034 14.0 0.1 0.93 9.4 0.0 2.4 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_11 PF08976.11 OWF40305.1 - 0.046 14.6 0.0 0.13 13.2 0.0 1.7 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 OWF40305.1 - 0.064 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I domain DIMCO_N PF16844.5 OWF40305.1 - 0.093 13.1 0.1 0.68 10.3 0.0 2.2 2 1 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal IMCp PF12314.8 OWF40306.1 - 3.4e-05 24.0 0.1 0.099 12.9 0.0 3.6 1 1 3 4 4 4 2 Inner membrane complex protein Glyco_hydro_30C PF17189.4 OWF40306.1 - 0.0096 16.1 2.0 23 5.3 0.8 4.4 1 1 1 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain nec1 PF10379.9 OWF40306.1 - 0.024 14.1 1.2 0.087 12.3 0.5 2.0 1 1 1 2 2 2 0 Virulence protein nec1 rpo30_N PF12410.8 OWF40306.1 - 9.6 6.1 13.8 18 5.3 0.5 3.4 1 1 2 3 3 3 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit IMCp PF12314.8 OWF40307.1 - 1.8e-06 28.1 0.0 0.16 12.3 0.0 3.8 1 1 3 4 4 4 2 Inner membrane complex protein nec1 PF10379.9 OWF40307.1 - 0.0084 15.6 4.9 0.13 11.7 0.9 2.8 1 1 2 3 3 3 2 Virulence protein nec1 rpo30_N PF12410.8 OWF40307.1 - 0.04 13.8 14.1 2.5 8.0 0.9 3.6 1 1 2 3 3 3 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Glyco_hydro_30C PF17189.4 OWF40307.1 - 0.097 12.9 4.4 39 4.6 0.1 4.6 2 2 1 3 3 3 0 Glycosyl hydrolase family 30 beta sandwich domain DUF3761 PF12587.8 OWF40307.1 - 1.2 9.6 11.4 14 6.2 0.9 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3761) IMCp PF12314.8 OWF40308.1 - 1.5e-10 41.3 3.1 2.3 8.5 0.0 6.2 1 1 4 6 6 6 5 Inner membrane complex protein nec1 PF10379.9 OWF40308.1 - 2.4e-06 27.2 10.6 0.38 10.2 0.6 4.4 1 1 5 6 6 6 6 Virulence protein nec1 Glyco_hydro_30C PF17189.4 OWF40308.1 - 0.043 14.0 8.7 70 3.8 0.3 7.2 2 2 2 4 4 4 0 Glycosyl hydrolase family 30 beta sandwich domain DUF3905 PF13045.6 OWF40308.1 - 6.3 6.9 9.1 7.2 6.7 0.3 4.1 1 1 5 6 6 6 0 Protein of unknown function (DUF3905) nec1 PF10379.9 OWF40309.1 - 1.5e-06 27.9 3.1 0.00023 20.7 0.8 2.7 1 1 2 3 3 3 2 Virulence protein nec1 Glyco_hydro_30C PF17189.4 OWF40309.1 - 0.0013 18.9 1.9 38 4.6 0.1 5.4 1 1 4 6 6 6 0 Glycosyl hydrolase family 30 beta sandwich domain Ubiquitin_2 PF14560.6 OWF40309.1 - 0.0015 18.9 2.5 6.1 7.4 0.1 3.5 2 1 2 4 4 4 2 Ubiquitin-like domain DUF1408 PF07193.11 OWF40309.1 - 0.0056 16.8 13.2 47 4.2 0.0 6.7 3 3 4 7 7 7 0 Protein of unknown function (DUF1408) IMCp PF12314.8 OWF40309.1 - 0.009 16.3 0.4 7.3 7.0 0.0 3.9 3 2 2 5 5 5 1 Inner membrane complex protein OTU PF02338.19 OWF40310.1 - 4.5e-10 40.1 0.0 1.2e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OWF40310.1 - 6.5e-06 25.8 0.1 0.086 12.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain HBS1_N PF08938.10 OWF40310.1 - 0.043 14.1 0.8 0.095 13.0 0.0 2.0 2 0 0 2 2 2 0 HBS1 N-terminus BPA_C PF18040.1 OWF40310.1 - 0.081 12.8 0.2 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 beta porphyranase A C-terminal IATP PF04568.12 OWF40310.1 - 0.52 10.8 6.3 2.6 8.5 6.3 2.2 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP FAM27 PF15832.5 OWF40310.1 - 0.71 10.5 7.8 2 9.0 0.4 2.6 2 0 0 2 2 2 0 FAM27 D and E protein family DUF726 PF05277.12 OWF40311.1 - 1.9e-125 418.4 0.4 2.5e-125 417.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) LCAT PF02450.15 OWF40311.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF5059 PF16502.5 OWF40311.1 - 0.027 13.2 0.1 0.039 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5059) DUF900 PF05990.12 OWF40311.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) EMC3_TMCO1 PF01956.16 OWF40311.1 - 0.077 12.7 0.1 4.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SseC PF04888.12 OWF40311.1 - 0.69 9.5 6.6 1.3 8.6 6.6 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family 5TM-5TMR_LYT PF07694.12 OWF40311.1 - 0.95 8.9 10.9 2.2 7.8 10.9 1.6 1 0 0 1 1 1 0 5TMR of 5TMR-LYT TTL PF03133.15 OWF40312.1 - 4.9e-58 196.6 2.4 8.7e-58 195.8 2.4 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF40312.1 - 1.2e-15 57.5 0.3 2.6e-07 30.2 0.0 2.7 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF40312.1 - 0.00017 21.0 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 OWF40312.1 - 0.0063 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GARS_A PF01071.19 OWF40312.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 OWF40312.1 - 0.11 12.0 0.1 9.5 5.8 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain NLPC_P60 PF00877.19 OWF40313.1 - 0.034 14.2 0.0 0.099 12.7 0.0 1.8 1 0 0 1 1 1 0 NlpC/P60 family HNOBA PF07701.14 OWF40314.1 - 3.9e-08 33.0 0.3 5.4e-08 32.5 0.3 1.2 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 OWF40314.1 - 5.2e-06 26.2 0.8 1e-05 25.2 0.3 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF720 PF05302.11 OWF40314.1 - 0.045 13.6 1.3 0.079 12.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Guanylate_cyc PF00211.20 OWF40315.1 - 7.6e-49 165.8 0.4 8.7e-49 165.6 0.4 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Forkhead PF00250.18 OWF40316.1 - 4.6e-38 129.4 0.1 1.1e-37 128.1 0.1 1.7 2 0 0 2 2 2 1 Forkhead domain SRPRB PF09439.10 OWF40317.1 - 7.2e-49 165.7 0.8 9.6e-49 165.3 0.8 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OWF40317.1 - 8.3e-11 41.6 0.3 1.3e-10 41.0 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF40317.1 - 2.7e-08 33.9 0.1 4.8e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OWF40317.1 - 3.1e-07 30.1 0.1 5.2e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF40317.1 - 2.9e-05 24.3 0.0 4.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OWF40317.1 - 0.00012 21.7 5.2 0.0055 16.3 0.2 2.5 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OWF40317.1 - 0.00018 21.1 0.6 0.00046 19.7 0.6 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OWF40317.1 - 0.00027 20.4 0.2 0.00038 19.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 OWF40317.1 - 0.033 14.6 0.1 0.087 13.3 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 OWF40317.1 - 0.094 12.6 0.3 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 OWF40317.1 - 0.12 11.9 1.1 0.67 9.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region BORCS8 PF10167.9 OWF40318.1 - 2.5e-41 140.1 3.8 3.5e-41 139.6 3.8 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Nup192 PF11894.8 OWF40318.1 - 0.0053 14.0 0.7 0.006 13.8 0.7 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF4142 PF13628.6 OWF40318.1 - 0.0058 16.9 1.8 0.0078 16.5 1.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) DUF2509 PF10713.9 OWF40319.1 - 1.4 9.1 7.0 0.45 10.6 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2509) BCAS2 PF05700.11 OWF40320.1 - 2.6e-75 252.6 8.8 3.1e-75 252.4 8.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF3440 PF11922.8 OWF40320.1 - 0.006 16.3 0.6 0.011 15.5 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3440) Helo_like_N PF17111.5 OWF40320.1 - 0.069 12.5 4.6 0.067 12.6 0.8 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Med9 PF07544.13 OWF40320.1 - 2 8.6 7.5 6.1 7.0 4.3 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Csm1_N PF18504.1 OWF40320.1 - 4.2 7.8 10.9 0.18 12.2 1.7 2.8 4 0 0 4 4 4 0 Csm1 N-terminal domain FlaC_arch PF05377.11 OWF40320.1 - 4.7 7.7 6.3 3.2 8.2 0.1 3.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) hSac2 PF12456.8 OWF40321.1 - 3.6e-19 68.6 0.1 5.4e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Inositol phosphatase Cadherin PF00028.17 OWF40322.1 - 1.2e-113 371.8 40.3 9.9e-24 83.6 1.5 14.5 14 0 0 14 14 14 13 Cadherin domain Cadherin_2 PF08266.12 OWF40322.1 - 1.8e-11 43.7 0.0 0.002 17.9 0.0 6.4 6 0 0 6 6 6 2 Cadherin-like Cadherin_pro PF08758.11 OWF40322.1 - 6.8e-11 42.2 3.8 5.5e-05 23.2 0.0 5.9 6 0 0 6 6 6 2 Cadherin prodomain like Cadherin_3 PF16184.5 OWF40322.1 - 3e-09 36.9 36.3 0.013 15.5 0.1 9.8 10 1 0 10 10 10 4 Cadherin-like PIGA PF08288.12 OWF40323.1 - 1e-44 151.0 1.1 1e-44 151.0 1.1 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OWF40323.1 - 3.6e-30 105.2 0.3 6e-30 104.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OWF40323.1 - 3.3e-24 85.3 0.0 6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OWF40323.1 - 4.5e-20 72.4 0.6 1.3e-19 71.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OWF40323.1 - 2e-11 44.6 0.0 6.3e-11 43.0 0.0 1.8 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OWF40323.1 - 0.0016 18.5 0.1 0.0035 17.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OWF40323.1 - 0.0018 18.6 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OWF40323.1 - 0.028 14.1 0.1 0.12 12.0 0.0 1.9 1 1 0 2 2 2 0 Starch synthase catalytic domain 14-3-3 PF00244.20 OWF40324.1 - 1.4e-80 270.0 1.7 2.1e-80 269.4 1.7 1.2 1 0 0 1 1 1 1 14-3-3 protein Glyco_hydro_9 PF00759.19 OWF40325.1 - 3.5e-13 49.8 3.8 8.6e-13 48.5 3.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 LSR PF05624.14 OWF40326.1 - 0.025 14.6 2.6 0.04 13.9 0.1 2.0 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Anophelin PF10731.9 OWF40326.1 - 0.12 12.2 0.8 0.18 11.7 0.8 1.4 1 1 0 1 1 1 0 Thrombin inhibitor from mosquito Laminin_G_3 PF13385.6 OWF40327.1 - 2.4e-19 70.0 23.4 1.7e-07 31.5 0.3 5.7 6 0 0 6 6 6 4 Concanavalin A-like lectin/glucanases superfamily VWD PF00094.25 OWF40327.1 - 1.7e-11 44.7 0.5 1.5e-10 41.6 0.5 2.9 1 1 0 1 1 1 1 von Willebrand factor type D domain F5_F8_type_C PF00754.25 OWF40327.1 - 8e-08 32.5 0.0 0.016 15.3 0.0 2.8 2 0 0 2 2 2 2 F5/8 type C domain EGF_2 PF07974.13 OWF40327.1 - 0.0025 18.1 74.2 0.022 15.1 16.0 5.0 4 0 0 4 4 4 3 EGF-like domain CD34_antigen PF06365.12 OWF40327.1 - 0.027 14.0 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family TMEM154 PF15102.6 OWF40327.1 - 0.72 9.8 0.0 0.72 9.8 0.0 4.6 5 1 0 5 5 5 0 TMEM154 protein family Lectin_C PF00059.21 OWF40328.1 - 5e-18 65.8 3.7 6.5e-18 65.4 3.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF40328.1 - 0.069 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF40329.1 - 4.3e-12 46.7 2.0 4.8e-12 46.6 2.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 OWF40330.1 - 3.3e-18 66.4 1.6 4.1e-18 66.1 1.6 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF40330.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Cu_amine_oxid PF01179.20 OWF40331.1 - 1.4e-110 370.0 4.5 1.7e-110 369.7 4.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OWF40331.1 - 8.3e-12 45.2 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OWF40331.1 - 9.8e-09 35.5 0.0 2.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DUF1965 PF09248.10 OWF40331.1 - 4e-05 23.3 0.0 9.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) DASH_Dam1 PF08653.10 OWF40332.1 - 3.2 7.6 8.2 4 7.3 0.2 4.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 SH3_2 PF07653.17 OWF40333.1 - 3.9e-35 119.3 3.1 4.1e-09 36.0 0.2 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 OWF40333.1 - 2.4e-34 116.7 24.4 1e-09 37.9 0.5 4.6 5 0 0 5 5 5 4 SH3 domain SH3_9 PF14604.6 OWF40333.1 - 1.6e-29 101.5 17.2 1.1e-08 34.8 0.1 4.8 5 0 0 5 5 5 4 Variant SH3 domain PX PF00787.24 OWF40333.1 - 1.7e-17 63.5 0.0 5.1e-17 61.9 0.0 1.9 1 0 0 1 1 1 1 PX domain SH3_3 PF08239.11 OWF40333.1 - 1e-09 38.5 17.7 0.0024 18.1 0.8 4.6 4 0 0 4 4 4 4 Bacterial SH3 domain SH3_4 PF06347.13 OWF40333.1 - 1.6e-07 31.0 20.0 0.0027 17.5 0.5 4.6 5 0 0 5 5 5 3 Bacterial SH3 domain Methyltranf_PUA PF13636.6 OWF40333.1 - 0.26 11.3 1.7 0.59 10.2 0.0 2.4 3 0 0 3 3 3 0 RNA-binding PUA-like domain of methyltransferase RsmF SH3_6 PF12913.7 OWF40333.1 - 1.3 8.6 11.4 2.3 7.9 0.3 3.8 3 1 0 3 3 3 0 SH3 domain (SH3b1 type) CEBP_ZZ PF16366.5 OWF40334.1 - 0.075 13.3 0.7 0.13 12.5 0.7 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Thr_synth_N PF14821.6 OWF40335.1 - 1.6e-24 85.9 0.0 8.6e-24 83.6 0.0 2.3 3 0 0 3 3 3 1 Threonine synthase N terminus PALP PF00291.25 OWF40335.1 - 6.3e-10 38.9 0.0 2.8e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF5024 PF16427.5 OWF40335.1 - 0.018 15.4 0.1 0.053 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) Glypican PF01153.19 OWF40335.1 - 0.11 11.3 1.1 0.18 10.6 1.1 1.2 1 0 0 1 1 1 0 Glypican GrpE PF01025.19 OWF40336.1 - 1.2e-45 155.2 4.3 1.5e-45 154.8 4.3 1.1 1 0 0 1 1 1 1 GrpE GOLGA2L5 PF15070.6 OWF40336.1 - 0.042 12.5 6.5 0.011 14.5 3.2 1.6 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 CLZ PF16526.5 OWF40336.1 - 0.048 14.0 3.3 0.13 12.6 3.3 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5094 PF17015.5 OWF40336.1 - 0.2 11.8 8.5 0.32 11.1 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Leu_zip PF15294.6 OWF40336.1 - 0.21 11.1 7.9 0.28 10.7 7.9 1.2 1 0 0 1 1 1 0 Leucine zipper Bac_small_YrzI PF09501.10 OWF40336.1 - 0.48 10.6 4.2 0.56 10.4 2.4 2.1 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) MFS_1 PF07690.16 OWF40337.1 - 2.5e-31 108.9 50.3 8.7e-26 90.7 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF40337.1 - 0.03 13.6 25.5 0.28 10.5 25.3 2.0 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 OWF40338.1 - 1.9e-24 86.3 50.0 1.6e-20 73.3 35.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM_bind PF09739.9 OWF40339.1 - 8.8e-184 612.2 0.0 1.1e-183 611.9 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Pkinase PF00069.25 OWF40340.1 - 4e-51 173.9 0.0 2.7e-37 128.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40340.1 - 5.5e-28 98.0 0.0 1.4e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.21 OWF40340.1 - 8.8e-08 31.7 0.0 0.0079 16.1 0.0 2.8 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 OWF40340.1 - 1.2e-05 25.0 0.2 0.16 11.5 0.0 2.9 1 1 2 3 3 3 3 PQQ-like domain Kdo PF06293.14 OWF40340.1 - 0.0065 15.8 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family NPR2 PF06218.11 OWF40340.1 - 0.0096 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Nitrogen permease regulator 2 SpdB PF05122.13 OWF40340.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Mobile element transfer protein APH PF01636.23 OWF40340.1 - 0.21 11.5 0.0 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4573 PF15140.6 OWF40341.1 - 1.1e-07 31.8 14.7 0.00073 19.4 3.4 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Candida_ALS_N PF11766.8 OWF40343.1 - 0.011 15.0 0.1 0.012 14.9 0.1 1.0 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding Plasmodium_HRP PF05403.11 OWF40343.1 - 0.043 13.6 18.0 0.051 13.4 18.0 1.0 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF4573 PF15140.6 OWF40343.1 - 0.17 11.7 0.6 0.21 11.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) RVT_1 PF00078.27 OWF40344.1 - 2e-07 30.7 0.1 2.2e-07 30.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) N_Asn_amidohyd PF14736.6 OWF40345.1 - 8.6e-97 323.5 0.0 1.1e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Annexin PF00191.20 OWF40346.1 - 1.1e-68 227.2 10.9 2.3e-18 66.0 0.1 5.4 5 1 0 5 5 5 4 Annexin YL1 PF05764.13 OWF40346.1 - 0.00022 21.5 5.8 0.00033 20.9 5.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Myb_DNA-bind_7 PF15963.5 OWF40346.1 - 0.0016 18.3 4.7 5.7 6.9 0.0 4.9 5 1 0 5 5 5 1 Myb DNA-binding like eIF3_subunit PF08597.10 OWF40346.1 - 0.02 14.8 9.9 0.038 13.9 9.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Sigma70_ner PF04546.13 OWF40346.1 - 0.043 13.7 12.4 6.1 6.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, non-essential region AdoHcyase PF05221.17 OWF40346.1 - 0.1 11.7 0.2 0.15 11.2 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase HBS1_N PF08938.10 OWF40346.1 - 0.11 12.8 6.6 0.57 10.5 3.8 2.8 2 0 0 2 2 2 0 HBS1 N-terminus CDC45 PF02724.14 OWF40346.1 - 0.11 10.7 5.2 0.15 10.3 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 OWF40346.1 - 0.15 12.0 7.8 0.3 11.1 7.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 TFIIF_alpha PF05793.12 OWF40346.1 - 0.23 10.0 13.6 6.1 5.3 13.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_RNA_Pol_19 PF05320.12 OWF40346.1 - 0.44 10.5 6.6 1.1 9.3 6.6 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit UPF0239 PF06783.11 OWF40346.1 - 0.49 10.6 4.7 1.3 9.2 4.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Sporozoite_P67 PF05642.11 OWF40346.1 - 0.93 7.5 2.7 1.3 7.0 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 OWF40346.1 - 2.1 8.8 9.3 5.8 7.4 9.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 OWF40346.1 - 2.8 9.0 15.4 4.9 8.2 14.0 2.2 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal Annexin PF00191.20 OWF40347.1 - 7.3e-80 263.0 1.5 8.8e-21 73.7 0.0 4.7 4 1 0 4 4 4 4 Annexin RXT2_N PF08595.11 OWF40347.1 - 0.0036 17.3 9.4 0.0083 16.2 9.4 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal Peptidase_S49_N PF08496.10 OWF40347.1 - 0.0048 17.0 1.4 0.016 15.2 1.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 N-terminal Afi1 PF07792.12 OWF40347.1 - 0.0072 16.8 6.4 0.017 15.6 6.4 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Pox_Ag35 PF03286.14 OWF40347.1 - 0.013 15.3 6.2 0.024 14.5 6.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AP3D1 PF06375.11 OWF40347.1 - 0.013 15.7 8.7 0.026 14.7 8.7 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TraT PF05818.12 OWF40347.1 - 0.027 14.1 5.4 0.063 13.0 5.4 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GEMIN8 PF15348.6 OWF40347.1 - 0.028 14.7 13.6 0.06 13.6 13.6 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 FAM176 PF14851.6 OWF40347.1 - 0.04 13.6 9.4 0.11 12.2 9.4 1.7 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 OWF40347.1 - 0.1 12.3 5.4 0.17 11.7 5.4 1.2 1 0 0 1 1 1 0 Connexin FYDLN_acid PF09538.10 OWF40347.1 - 0.1 13.3 7.0 0.083 13.6 5.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) RPA43_OB PF17875.1 OWF40347.1 - 0.11 13.2 1.9 0.23 12.1 1.9 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Spot_14 PF07084.12 OWF40347.1 - 0.13 12.4 7.2 0.28 11.3 7.2 1.5 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 PPL5 PF18168.1 OWF40347.1 - 0.14 11.5 8.6 0.23 10.7 8.6 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Myc_N PF01056.18 OWF40347.1 - 0.22 11.4 7.5 0.39 10.6 7.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Spt20 PF12090.8 OWF40347.1 - 0.22 11.1 11.2 0.43 10.2 11.2 1.4 1 0 0 1 1 1 0 Spt20 family DUF4820 PF16091.5 OWF40347.1 - 0.23 10.8 9.2 0.43 9.9 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3486 PF11985.8 OWF40347.1 - 0.25 11.7 11.1 2.7 8.4 8.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) Eapp_C PF10238.9 OWF40347.1 - 0.29 11.2 8.1 0.59 10.2 8.1 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Zip PF02535.22 OWF40347.1 - 0.4 9.9 1.6 0.56 9.4 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 OWF40347.1 - 0.61 10.2 2.9 0.96 9.6 2.9 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 OWF40347.1 - 0.63 8.7 6.4 0.91 8.2 6.4 1.1 1 0 0 1 1 1 0 Presenilin Nucleo_P87 PF07267.11 OWF40347.1 - 0.75 8.6 12.0 0.29 10.0 9.5 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DUF4746 PF15928.5 OWF40347.1 - 1.5 8.2 14.7 2.5 7.5 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 OWF40347.1 - 2.4 7.4 9.2 4 6.7 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein BORG_CEP PF14957.6 OWF40347.1 - 2.5 9.3 5.2 5.5 8.2 5.2 1.5 1 0 0 1 1 1 0 Cdc42 effector CDC45 PF02724.14 OWF40347.1 - 3.8 5.7 10.1 5.7 5.1 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein YABBY PF04690.13 OWF40347.1 - 5.7 7.5 6.2 13 6.3 6.2 1.5 1 0 0 1 1 1 0 YABBY protein DUF3464 PF11947.8 OWF40347.1 - 6 6.6 8.7 11 5.7 8.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 VIR_N PF15912.5 OWF40347.1 - 6.3 6.3 10.8 0.1 12.2 2.9 1.9 3 0 0 3 3 2 0 Virilizer, N-terminal Ribosomal_60s PF00428.19 OWF40347.1 - 6.6 7.4 11.4 19 5.9 11.4 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.6 OWF40347.1 - 6.7 7.2 13.9 0.96 9.9 9.2 2.0 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paf1 PF03985.13 OWF40347.1 - 7.2 5.5 18.2 11 4.8 18.2 1.2 1 0 0 1 1 1 0 Paf1 Saw1 PF11561.8 OWF40347.1 - 7.9 5.9 8.2 19 4.7 8.2 1.5 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Annexin PF00191.20 OWF40348.1 - 6.2e-11 42.2 2.1 0.0033 17.4 0.0 3.3 3 0 0 3 3 3 3 Annexin YL1 PF05764.13 OWF40348.1 - 0.27 11.3 10.1 0.29 11.2 9.1 1.5 2 0 0 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.6 OWF40348.1 - 0.62 10.5 8.6 1.3 9.5 8.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0239 PF06783.11 OWF40348.1 - 4.1 7.7 7.0 8.9 6.6 7.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Annexin PF00191.20 OWF40349.1 - 8.9e-79 259.5 0.5 1.7e-19 69.7 0.0 4.7 4 1 0 4 4 4 4 Annexin Peptidase_S49_N PF08496.10 OWF40349.1 - 0.02 14.9 1.8 0.034 14.2 1.2 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RXT2_N PF08595.11 OWF40349.1 - 0.025 14.6 6.2 0.05 13.6 6.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Afi1 PF07792.12 OWF40349.1 - 0.15 12.5 4.7 0.38 11.2 4.7 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Connexin PF00029.19 OWF40349.1 - 0.19 11.5 3.2 0.29 10.8 3.2 1.2 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 OWF40349.1 - 0.25 11.0 8.7 0.41 10.2 8.7 1.3 1 0 0 1 1 1 0 Spt20 family FAM176 PF14851.6 OWF40349.1 - 0.32 10.7 7.2 0.45 10.2 4.9 2.1 2 0 0 2 2 2 0 FAM176 family Eapp_C PF10238.9 OWF40349.1 - 0.63 10.1 7.2 1.2 9.2 7.2 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein PPL5 PF18168.1 OWF40349.1 - 0.69 9.1 5.9 1.2 8.4 5.9 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF4175 PF13779.6 OWF40349.1 - 1.2 7.0 13.0 1.8 6.3 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 OWF40349.1 - 1.5 7.5 4.5 2.2 7.0 4.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 OWF40349.1 - 1.9 7.8 7.7 3.6 6.9 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4746 PF15928.5 OWF40349.1 - 3.3 7.0 9.2 5.5 6.3 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vpu PF00558.19 OWF40349.1 - 7.8 6.4 6.6 16 5.3 6.6 1.5 1 0 0 1 1 1 0 Vpu protein Lectin_C PF00059.21 OWF40350.1 - 2e-11 44.6 0.3 4.5e-11 43.4 0.3 1.6 1 0 0 1 1 1 1 Lectin C-type domain Adeno_E3_CR2 PF02439.15 OWF40350.1 - 0.032 14.0 0.1 0.066 13.0 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OWF40350.1 - 0.049 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 OWF40350.1 - 0.12 13.2 0.0 0.28 12.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Macro PF01661.21 OWF40351.1 - 5.5e-30 103.8 0.1 9.4e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.5 OWF40351.1 - 2.2e-15 56.1 0.1 2.2e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 OWF40351.1 - 3.4e-14 53.3 0.0 3.4e-14 53.3 0.0 2.4 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OWF40351.1 - 3.7e-05 23.9 0.0 8.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.20 OWF40351.1 - 0.029 14.5 0.2 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component YihI PF04220.12 OWF40351.1 - 0.03 14.0 0.0 0.03 14.0 0.0 2.0 2 0 0 2 2 2 0 Der GTPase activator (YihI) BLOC1_2 PF10046.9 OWF40352.1 - 1.4e-34 118.3 6.8 1.8e-34 117.9 6.8 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 OWF40352.1 - 2.4e-05 24.5 0.4 4.4e-05 23.7 0.4 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Med9 PF07544.13 OWF40352.1 - 0.00063 19.8 1.8 0.0011 19.0 1.8 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DASH_Dam1 PF08653.10 OWF40352.1 - 0.0075 16.0 0.2 0.024 14.4 0.1 1.9 1 1 1 2 2 2 1 DASH complex subunit Dam1 Imm6 PF14434.6 OWF40352.1 - 0.0091 15.9 0.5 0.018 15.0 0.4 1.6 1 1 0 1 1 1 1 Immunity protein Imm6 ParB PF08775.10 OWF40352.1 - 0.0094 16.4 2.4 0.016 15.7 2.4 1.4 1 0 0 1 1 1 1 ParB family Seryl_tRNA_N PF02403.22 OWF40352.1 - 0.012 15.8 1.2 0.018 15.3 1.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HAD_2 PF13419.6 OWF40352.1 - 0.013 15.6 3.2 0.015 15.4 2.9 1.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase THOC7 PF05615.13 OWF40352.1 - 0.022 15.1 2.3 0.03 14.6 2.3 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF2443 PF10398.9 OWF40352.1 - 0.028 14.5 1.2 0.05 13.7 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) Laminin_II PF06009.12 OWF40352.1 - 0.033 14.2 0.6 0.046 13.7 0.6 1.4 1 0 0 1 1 1 0 Laminin Domain II PRF PF06875.11 OWF40352.1 - 0.038 13.4 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF DUF1664 PF07889.12 OWF40352.1 - 0.1 12.6 0.5 0.13 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 OWF40352.1 - 0.12 12.9 2.0 0.21 12.1 1.5 1.8 1 1 0 1 1 1 0 Spectrin repeat Tweety PF04906.13 OWF40352.1 - 0.13 10.9 0.4 0.16 10.6 0.4 1.1 1 0 0 1 1 1 0 Tweety SKA2 PF16740.5 OWF40352.1 - 0.13 12.0 3.5 1.7 8.4 0.9 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Gly_acyl_tr_C PF08444.10 OWF40352.1 - 0.14 12.4 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region TMPIT PF07851.13 OWF40352.1 - 0.16 11.2 1.9 0.2 10.9 1.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0489 PF12640.7 OWF40353.1 - 2.1e-18 67.2 2.2 1e-17 64.9 2.2 2.0 1 1 0 1 1 1 1 UPF0489 domain BACK PF07707.15 OWF40354.1 - 4.2e-08 33.2 0.1 5.9e-08 32.8 0.1 1.3 1 1 0 1 1 1 1 BTB And C-terminal Kelch Sulfatase PF00884.23 OWF40355.1 - 4.5e-74 249.6 0.0 6.7e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OWF40355.1 - 2.1e-23 83.4 0.1 3.2e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OWF40355.1 - 3.7e-07 30.1 1.1 4e-06 26.7 1.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase LPMO_10 PF03067.15 OWF40356.1 - 3.1e-33 116.1 0.7 6.2e-33 115.1 0.7 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Carbam_trans_N PF02543.15 OWF40357.1 - 0.046 13.4 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Casc1_N PF15927.5 OWF40357.1 - 0.12 12.1 3.3 6.8 6.3 0.0 2.8 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus DUF1406 PF07190.11 OWF40358.1 - 0.018 15.0 3.2 0.072 13.0 3.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) Ank_2 PF12796.7 OWF40359.1 - 3e-21 75.8 0.0 1.8e-10 41.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF40359.1 - 3.9e-13 49.6 0.1 1.2e-06 28.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SAM_1 PF00536.30 OWF40359.1 - 2e-11 44.1 0.2 5.6e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 OWF40359.1 - 2e-10 40.7 0.3 0.00022 21.4 0.0 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF40359.1 - 1.7e-09 37.1 0.0 0.00065 20.0 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OWF40359.1 - 8.3e-07 29.2 0.4 0.051 14.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat SAM_2 PF07647.17 OWF40359.1 - 5.7e-05 23.1 0.6 0.00038 20.5 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Endotoxin_M PF00555.19 OWF40359.1 - 8 6.5 10.5 2.4 8.2 5.6 2.1 1 1 1 2 2 2 0 delta endotoxin PTR2 PF00854.21 OWF40362.1 - 1.2e-92 310.8 25.7 3.9e-91 305.8 21.2 2.8 2 1 0 2 2 2 1 POT family ENTH PF01417.20 OWF40363.1 - 1.4e-49 167.3 0.3 1.9e-49 166.8 0.3 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OWF40363.1 - 1.4e-06 27.5 0.1 1.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 OWF40363.1 - 7.1e-05 22.7 0.3 9.1e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 VHS domain Cgr1 PF03879.14 OWF40363.1 - 0.071 13.5 3.3 0.12 12.8 3.3 1.3 1 0 0 1 1 1 0 Cgr1 family Glycos_transf_2 PF00535.26 OWF40365.1 - 6.2e-22 78.2 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OWF40365.1 - 3.1e-05 23.6 0.2 0.034 13.6 0.1 2.2 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF40365.1 - 0.00022 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF40365.1 - 0.027 14.4 0.1 0.073 13.0 0.1 1.6 1 1 1 2 2 2 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF40366.1 - 7.5e-28 97.5 0.0 1.3e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OWF40366.1 - 2.1e-06 27.4 0.0 4.8e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF40366.1 - 0.00028 20.5 0.0 0.00072 19.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF40366.1 - 0.00095 19.1 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF40367.1 - 1.1e-25 90.5 0.0 2.8e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OWF40367.1 - 1.9e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF40367.1 - 0.00029 20.4 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF1887 PF09002.11 OWF40367.1 - 0.018 13.8 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Ricin_B_lectin PF00652.22 OWF40367.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF2207 PF09972.9 OWF40368.1 - 0.016 14.0 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AOC_like PF18678.1 OWF40368.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain Tissue_fac PF01108.17 OWF40368.1 - 0.18 11.7 0.9 0.84 9.5 0.7 2.2 2 0 0 2 2 2 0 Tissue factor Interfer-bind PF09294.10 OWF40368.1 - 0.52 10.7 5.4 17 5.8 0.0 3.4 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 OWF40369.1 - 3.2e-12 46.6 10.4 0.0016 18.8 0.1 5.0 5 1 0 5 5 5 3 Fibronectin type III domain Ig_3 PF13927.6 OWF40369.1 - 3.9e-05 24.2 2.9 0.0027 18.3 0.1 3.8 3 1 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 OWF40369.1 - 0.0023 18.3 9.8 0.052 13.9 0.1 4.2 4 1 1 5 5 5 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 OWF40369.1 - 0.026 15.1 9.3 11 6.7 0.1 4.6 3 1 1 4 4 4 0 Purple acid Phosphatase, N-terminal domain GPI-anchored PF10342.9 OWF40369.1 - 0.035 14.9 6.2 0.27 12.0 0.0 4.2 5 0 0 5 5 5 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SusE PF14292.6 OWF40369.1 - 0.078 13.2 0.6 13 6.1 0.1 2.9 3 0 0 3 3 3 0 SusE outer membrane protein DUF3978 PF13123.6 OWF40369.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) Ig_Tie2_1 PF10430.9 OWF40369.1 - 0.23 11.9 2.4 1.1 9.8 0.1 3.1 4 0 0 4 4 4 0 Tie-2 Ig-like domain 1 fn3 PF00041.21 OWF40370.1 - 6.8e-21 74.4 10.7 1.6e-05 25.2 0.4 4.8 4 0 0 4 4 4 4 Fibronectin type III domain SUR7 PF06687.12 OWF40370.1 - 0.011 15.4 0.3 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 SUR7/PalI family Glycophorin_A PF01102.18 OWF40370.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.4 4 0 0 4 4 4 0 Glycophorin A PAGK PF15284.6 OWF40371.1 - 0.0066 16.3 9.2 3.7 7.5 0.0 4.6 3 2 2 5 5 5 3 Phage-encoded virulence factor EKAL PF17986.1 OWF40371.1 - 0.066 13.3 0.6 43 4.3 0.0 4.4 5 1 0 6 6 6 0 EMP3-KAHRP-like N-terminal domain Rhodanese PF00581.20 OWF40371.1 - 0.069 13.7 3.4 46 4.6 0.0 4.5 3 1 1 4 4 4 0 Rhodanese-like domain DUF4352 PF11611.8 OWF40371.1 - 0.18 12.1 0.1 13 6.1 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4352) PDEase_I PF00233.19 OWF40373.1 - 2.4e-90 302.4 6.7 2.4e-90 302.4 6.7 2.4 3 1 1 4 4 4 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 OWF40373.1 - 1.1e-50 171.2 11.6 5.9e-48 162.4 10.4 3.1 2 1 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) VCBS PF13517.6 OWF40374.1 - 5.1e-12 46.2 10.4 3.2e-05 24.4 0.1 3.9 3 2 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PliI PF16743.5 OWF40374.1 - 1.1e-05 25.1 0.0 0.088 12.6 0.0 2.3 2 0 0 2 2 2 2 Periplasmic lysozyme inhibitor of I-type lysozyme FG-GAP PF01839.23 OWF40374.1 - 1.5e-05 25.0 14.7 0.00027 21.0 0.8 3.5 3 0 0 3 3 3 2 FG-GAP repeat TcdB_toxin_midN PF12256.8 OWF40374.1 - 0.016 14.6 0.2 0.71 9.2 0.0 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.6 OWF40374.1 - 0.3 10.7 0.1 0.3 10.7 0.1 3.9 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.32 OWF40374.1 - 2.7 7.7 11.0 4 7.2 0.1 4.0 4 0 0 4 4 4 0 EF hand SSF PF00474.17 OWF40375.1 - 1.9e-41 142.3 23.5 1.9e-41 142.3 23.5 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family Pam17 PF08566.10 OWF40375.1 - 1.4 8.7 5.3 4.9 7.0 0.7 3.2 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Glyco_transf_54 PF04666.13 OWF40376.1 - 3.2e-25 88.6 0.2 4.8e-25 88.0 0.2 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Lectin_C PF00059.21 OWF40377.1 - 9.7e-18 64.9 1.4 2e-17 63.9 1.4 1.6 1 0 0 1 1 1 1 Lectin C-type domain CBM_14 PF01607.24 OWF40377.1 - 0.0038 17.4 4.2 0.013 15.7 4.2 1.9 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain MgtE_N PF03448.17 OWF40377.1 - 0.24 12.0 0.3 0.47 11.1 0.3 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain 7tm_1 PF00001.21 OWF40380.1 - 1.6e-09 37.5 6.5 1.6e-09 37.5 6.5 2.9 2 1 1 3 3 3 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF40380.1 - 0.0048 16.6 7.0 0.0048 16.6 7.0 2.7 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2975 PF11188.8 OWF40380.1 - 0.18 11.7 16.6 0.12 12.2 2.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Tetraspanin PF00335.20 OWF40380.1 - 9.3 5.9 14.7 0.061 13.0 2.0 3.0 3 1 0 3 3 3 0 Tetraspanin family VEGFR-2_TMD PF17988.1 OWF40381.1 - 0.52 9.8 9.6 0.93 9.0 9.6 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Renin_r PF07850.14 OWF40381.1 - 1.3 9.7 3.1 1.8 9.2 3.1 1.2 1 0 0 1 1 1 0 Renin receptor-like protein Pkinase PF00069.25 OWF40383.1 - 1.5e-64 217.9 0.0 1.9e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40383.1 - 1.4e-36 126.1 0.0 1.8e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF40383.1 - 1.9e-05 24.1 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF40383.1 - 0.00024 20.0 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OWF40383.1 - 0.22 11.4 0.0 0.35 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_8 PF13855.6 OWF40384.1 - 0.0027 17.4 1.1 21 5.0 0.1 4.6 1 1 3 4 4 4 3 Leucine rich repeat RE_ScaI PF09569.10 OWF40384.1 - 0.025 14.3 3.2 38 3.9 0.0 4.4 1 1 4 5 5 5 0 ScaI restriction endonuclease DUF2813 PF11398.8 OWF40384.1 - 0.26 10.5 5.2 13 4.9 0.2 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF2813) CheF-arch PF04283.12 OWF40384.1 - 0.26 11.0 0.0 60 3.3 0.0 3.3 1 1 2 3 3 3 0 Chemotaxis signal transduction system protein F from archaea zf-CCCH_3 PF15663.5 OWF40385.1 - 1.4e-29 102.5 6.2 4.5e-29 100.9 6.2 1.9 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 OWF40385.1 - 0.28 11.7 16.8 5.5 7.6 1.9 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger KH_1 PF00013.29 OWF40386.1 - 2.7e-10 39.9 0.1 0.00023 20.9 0.0 4.1 3 1 1 4 4 4 3 KH domain KH_2 PF07650.17 OWF40386.1 - 0.0078 16.0 4.3 2.1 8.2 0.2 4.8 4 2 0 4 4 4 1 KH domain Spc110_C PF18520.1 OWF40386.1 - 0.2 11.3 2.0 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain Rubrerythrin PF02915.17 OWF40386.1 - 0.81 10.1 3.3 16 5.9 0.4 2.6 2 1 0 3 3 3 0 Rubrerythrin SLS PF14611.6 OWF40386.1 - 1.1 9.0 4.9 20 4.9 0.8 3.1 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator rRNA_processing PF08524.11 OWF40387.1 - 6.6e-18 65.1 29.9 6.6e-18 65.1 29.9 1.4 1 1 0 1 1 1 1 rRNA processing MAP7 PF05672.11 OWF40387.1 - 0.07 12.8 21.8 0.13 11.9 21.8 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Proton_antipo_C PF01010.19 OWF40387.1 - 3.5 7.2 6.0 7.3 6.1 4.1 2.0 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus 2OG-FeII_Oxy_3 PF13640.6 OWF40388.1 - 7.5e-11 42.8 0.0 1.3e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 OWF40388.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.5 1 1 0 1 1 1 0 Poxvirus C4/C10 protein PhyH PF05721.13 OWF40388.1 - 0.053 13.8 0.0 11 6.2 0.0 2.2 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Atg8 PF02991.16 OWF40389.1 - 5.3e-41 139.0 0.4 6.1e-41 138.8 0.4 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OWF40389.1 - 1.2e-06 28.8 0.1 2e-06 28.1 0.1 1.4 1 1 1 2 2 2 1 Ubiquitin-like autophagy protein Apg12 DUF1918 PF08940.11 OWF40391.1 - 0.23 11.1 0.5 13 5.5 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1918) VCX_VCY PF15231.6 OWF40391.1 - 0.9 10.2 4.0 2.9 8.6 0.6 1.8 1 1 0 1 1 1 0 Variable charge X/Y family DUF2816 PF10992.8 OWF40392.1 - 6.3e-05 22.8 27.0 11 6.0 0.8 7.7 1 1 3 4 4 4 2 Protein of unknown function (DUF2816) LolA_like PF17131.4 OWF40392.1 - 0.00092 19.0 3.1 3.5 7.3 0.1 3.9 1 1 2 4 4 4 2 Outer membrane lipoprotein-sorting protein UPAR_LY6_2 PF16975.5 OWF40392.1 - 0.0089 16.2 11.6 8.4 6.7 0.1 5.9 1 1 7 8 8 8 1 Ly6/PLAUR domain-containing protein 6, Lypd6 AHJR-like PF18743.1 OWF40392.1 - 0.032 13.8 0.2 20 4.8 0.0 3.9 1 1 4 6 6 6 0 REase_AHJR-like DUF4879 PF16219.5 OWF40392.1 - 0.19 11.9 4.9 45 4.3 0.0 5.5 1 1 5 7 7 7 0 Domain of unknown function (DUF4879) Amb_V_allergen PF03913.13 OWF40392.1 - 0.75 9.8 11.4 60 3.7 0.4 6.0 2 2 4 6 6 6 0 Amb V Allergen Globin PF00042.22 OWF40393.1 - 1e-19 71.1 0.2 3e-19 69.6 0.2 1.8 1 1 0 1 1 1 1 Globin PepSY_TM PF03929.16 OWF40393.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Globin PF00042.22 OWF40394.1 - 1.6e-06 28.6 0.1 1.8e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 Globin Es2 PF09751.9 OWF40395.1 - 7.2e-82 276.4 13.8 7.2e-82 276.4 13.8 2.2 2 0 0 2 2 2 1 Nuclear protein Es2 C1q PF00386.21 OWF40396.1 - 1.6e-19 70.4 0.0 2.8e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 C1q domain SKA1 PF07160.12 OWF40396.1 - 0.0016 18.3 0.4 0.0021 18.0 0.4 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF4172 PF13776.6 OWF40396.1 - 0.011 16.1 0.3 0.033 14.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) YabA PF06156.13 OWF40396.1 - 0.021 15.4 1.7 0.037 14.6 1.7 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF1631 PF07793.11 OWF40396.1 - 0.022 13.2 0.1 0.026 12.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) BclA_C PF18573.1 OWF40396.1 - 0.029 14.3 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 BclA C-terminal domain DUF1664 PF07889.12 OWF40396.1 - 0.047 13.7 0.3 0.079 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF848 PF05852.11 OWF40396.1 - 0.048 13.8 2.4 0.09 12.9 2.4 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Cnn_1N PF07989.11 OWF40396.1 - 0.048 13.8 2.1 0.093 12.9 0.6 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Dsh_C PF12316.8 OWF40396.1 - 0.084 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SlyX PF04102.12 OWF40396.1 - 8 7.2 6.5 11 6.7 0.3 2.4 1 1 1 2 2 2 0 SlyX Gal-3-0_sulfotr PF06990.11 OWF40397.1 - 4.2e-38 131.3 0.4 5.1e-38 131.0 0.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF40397.1 - 0.004 17.1 0.6 0.052 13.4 0.2 2.3 2 1 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 OWF40398.1 - 1.5e-49 168.9 0.4 1.9e-49 168.6 0.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF40398.1 - 0.011 15.6 0.1 0.025 14.5 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase family Nucleotid_trans PF03407.16 OWF40399.1 - 1.9e-15 57.4 0.0 7.1e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Lipase_GDSL_2 PF13472.6 OWF40400.1 - 2.1e-06 28.2 0.0 2.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF40400.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF1488 PF07369.11 OWF40400.1 - 0.042 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) TPR_12 PF13424.6 OWF40401.1 - 2.8e-27 94.8 26.2 1.6e-11 44.3 2.1 6.6 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 OWF40401.1 - 2.1e-21 75.1 7.7 1.8e-09 37.1 0.3 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF40401.1 - 1.3e-10 40.6 14.5 0.00016 21.4 0.3 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF40401.1 - 1.1e-08 34.4 7.3 0.00066 19.5 0.3 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF40401.1 - 2e-07 30.7 11.7 0.00079 19.4 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF40401.1 - 8.8e-06 25.5 13.8 1.1 9.5 0.3 6.3 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF40401.1 - 3.5e-05 24.3 3.0 59 4.9 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF40401.1 - 0.011 15.1 4.0 2.4 7.5 0.9 3.6 1 1 2 4 4 4 0 MalT-like TPR region TPR_17 PF13431.6 OWF40401.1 - 0.016 15.6 1.0 7.8 7.1 0.2 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF40401.1 - 0.079 13.6 10.9 7.6 7.3 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MTP18 PF10558.9 OWF40402.1 - 4.8e-21 75.5 0.7 2.5e-10 40.6 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) ApoC-I PF04691.12 OWF40402.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Stathmin PF00836.19 OWF40403.1 - 0.005 16.8 2.3 0.0065 16.4 2.3 1.3 1 0 0 1 1 1 1 Stathmin family KfrA_N PF11740.8 OWF40403.1 - 0.048 14.3 0.1 0.072 13.8 0.1 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Plk4_PB2 PF18409.1 OWF40403.1 - 0.097 13.4 1.0 0.17 12.6 1.0 1.4 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 SLATT_fungal PF18142.1 OWF40403.1 - 1 9.4 3.7 1.6 8.8 3.7 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain XhlA PF10779.9 OWF40403.1 - 6 7.2 6.0 14 6.0 4.4 2.2 2 1 0 2 2 2 0 Haemolysin XhlA ERM PF00769.19 OWF40404.1 - 5.7e-56 190.1 43.8 5.7e-56 190.1 43.8 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.18 OWF40404.1 - 3.7e-26 91.8 0.7 3.7e-26 91.8 0.7 3.1 2 1 1 3 3 3 1 FERM central domain FERM_C PF09380.10 OWF40404.1 - 2.2e-25 88.8 0.5 6.7e-25 87.3 0.0 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 OWF40404.1 - 3.7e-13 49.2 0.8 3.7e-10 39.6 0.0 3.8 3 1 0 3 3 3 2 FERM N-terminal domain Transport_MerF PF11431.8 OWF40405.1 - 0.15 12.0 26.2 1.8 8.5 0.4 6.5 3 2 3 6 6 6 0 Membrane transport protein MerF SH3_9 PF14604.6 OWF40406.1 - 0.0017 18.2 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF40406.1 - 0.013 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Dockerin_1 PF00404.18 OWF40407.1 - 0.038 14.2 0.0 3 8.1 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain Gemini_AC4_5 PF04807.12 OWF40407.1 - 0.044 13.5 17.8 8.4 6.2 0.3 7.1 4 2 3 7 7 7 0 Geminivirus AC4/5 conserved region BamHI PF02923.15 OWF40407.1 - 0.045 13.5 0.1 0.088 12.6 0.1 1.5 1 1 0 1 1 1 0 Restriction endonuclease BamHI Ephrin PF00812.17 OWF40408.1 - 0.68 9.9 6.6 0.13 12.3 1.5 2.2 2 0 0 2 2 2 0 Ephrin ShK PF01549.24 OWF40408.1 - 1.1 9.9 12.4 0.62 10.6 9.2 2.4 2 0 0 2 2 2 0 ShK domain-like Zip PF02535.22 OWF40412.1 - 4.5e-62 210.2 12.5 2.7e-61 207.6 12.5 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DNA_ligase_A_C PF04679.15 OWF40412.1 - 0.091 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DUF3899 PF13038.6 OWF40412.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.7 3 2 2 5 5 5 0 Domain of unknown function (DUF3899) DUF4834 PF16118.5 OWF40412.1 - 0.75 10.8 0.0 0.75 10.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) ThrE PF06738.12 OWF40412.1 - 7.5 5.8 12.5 0.78 9.1 7.7 1.8 2 0 0 2 2 2 0 Putative threonine/serine exporter Neur_chan_LBD PF02931.23 OWF40413.1 - 5.2e-36 124.1 0.5 7.9e-36 123.5 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF40413.1 - 3.7e-21 76.3 13.8 1.1e-19 71.5 6.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region KRTAP PF11759.8 OWF40414.1 - 1.1 9.9 5.4 2.2 8.9 5.4 1.6 1 0 0 1 1 1 0 Keratin-associated matrix Dimer_Tnp_hAT PF05699.14 OWF40416.1 - 6.1e-15 54.8 0.1 8e-15 54.4 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Torus PF16131.5 OWF40417.1 - 1.4e-06 28.9 0.7 2.9e-06 28.0 0.7 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 OWF40417.1 - 2.6e-06 27.1 6.1 4.5e-06 26.3 6.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OWF40417.1 - 0.00017 21.4 6.4 0.0003 20.6 6.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF40417.1 - 0.00074 19.5 10.5 0.0015 18.5 10.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 OWF40417.1 - 3.7 8.2 6.1 6 7.5 6.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Dynamin_N PF00350.23 OWF40418.1 - 3.3e-08 33.8 0.5 3.9e-07 30.3 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF40418.1 - 2.9e-07 30.6 0.0 1.1e-06 28.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OWF40418.1 - 0.015 15.6 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF2207 PF09972.9 OWF40418.1 - 0.035 12.9 0.1 0.055 12.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNase_J_C PF17770.1 OWF40418.1 - 0.037 15.1 1.2 0.1 13.7 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain RsgA_GTPase PF03193.16 OWF40418.1 - 0.041 13.8 0.2 0.21 11.5 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 OWF40418.1 - 0.043 13.4 0.0 0.094 12.2 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SNF PF00209.18 OWF40419.1 - 1.4e-201 670.7 36.7 1.7e-201 670.5 36.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Inhibitor_I36 PF03995.13 OWF40419.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor family I36 LRR_8 PF13855.6 OWF40420.1 - 1e-19 70.0 14.8 4.4e-09 36.0 0.2 7.3 4 3 4 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 OWF40420.1 - 2.7e-06 27.6 28.6 0.045 14.2 0.2 8.0 4 2 7 12 12 12 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF40420.1 - 0.00018 21.3 26.6 1.2 9.4 0.3 8.2 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.33 OWF40420.1 - 0.00034 20.8 20.1 16 6.5 0.1 9.6 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_5 PF13306.6 OWF40420.1 - 0.00052 20.0 2.6 0.0017 18.4 0.1 3.0 2 2 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF40420.1 - 0.027 14.0 0.3 0.027 14.0 0.3 1.8 2 0 0 2 2 2 0 Leucine-rich repeat TIR_2 PF13676.6 OWF40421.1 - 0.00022 21.8 0.0 0.00024 21.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF40421.1 - 0.00031 20.6 0.7 0.00041 20.2 0.7 1.2 1 0 0 1 1 1 1 TIR domain Aldolase_II PF00596.21 OWF40422.1 - 1.6e-45 155.4 0.5 2.5e-45 154.7 0.5 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3853 PF12964.7 OWF40422.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) GerD PF17898.1 OWF40422.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.5 3 0 0 3 3 3 0 Spore germination GerD central core domain WD40 PF00400.32 OWF40423.1 - 2.3e-12 47.2 6.2 0.0012 19.7 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF40423.1 - 1.8e-08 34.6 0.0 0.00026 21.2 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF40423.1 - 9.7e-06 24.8 0.4 0.00012 21.1 0.0 2.5 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein OSCP PF00213.18 OWF40423.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Cytochrom_D1 PF02239.16 OWF40423.1 - 0.015 13.8 0.0 0.11 11.0 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain MecA PF05389.12 OWF40423.1 - 0.085 12.5 1.6 0.29 10.7 2.1 1.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) CN_hydrolase PF00795.22 OWF40424.1 - 3.8e-64 216.5 0.0 4.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TIR PF01582.20 OWF40425.1 - 0.0026 17.6 0.2 0.0031 17.3 0.2 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF40425.1 - 0.047 14.3 0.0 0.061 13.9 0.0 1.3 1 1 0 1 1 1 0 TIR domain IES5 PF17335.2 OWF40425.1 - 0.11 12.8 0.1 8.9 6.6 0.0 2.1 1 1 1 2 2 2 0 Ino80 complex subunit 5 ATP-synt_S1 PF05827.12 OWF40426.1 - 1.5e-42 144.9 0.3 2.8e-42 144.0 0.3 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) LIM_bind PF01803.16 OWF40426.1 - 0.016 14.8 0.1 3.5 7.1 0.1 2.2 1 1 1 2 2 2 0 LIM-domain binding protein Ribosom_S12_S23 PF00164.25 OWF40427.1 - 8.7e-50 167.1 1.0 1.1e-49 166.8 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CYYR1 PF10873.8 OWF40428.1 - 2.7e-07 31.1 32.5 2.7e-07 31.1 32.5 1.9 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 Shisa PF13908.6 OWF40428.1 - 0.0052 17.1 4.7 0.0052 17.1 4.7 2.7 1 1 2 3 3 3 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF40428.1 - 0.014 16.3 0.0 0.025 15.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Prominin PF05478.11 OWF40428.1 - 9.9 4.0 6.0 14 3.5 6.0 1.1 1 0 0 1 1 1 0 Prominin Adeno_E3_CR2 PF02439.15 OWF40429.1 - 0.0024 17.6 2.1 0.0024 17.6 2.1 2.0 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 Lipocalin PF00061.23 OWF40430.1 - 3.2e-07 30.6 0.4 4.1e-07 30.3 0.4 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Glu-tRNAGln PF02686.15 OWF40431.1 - 4.8e-09 36.4 0.4 9.2e-09 35.5 0.2 1.5 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit zf-B_box PF00643.24 OWF40432.1 - 3.2e-06 27.2 5.2 3.2e-06 27.2 5.2 2.1 2 0 0 2 2 2 1 B-box zinc finger GAS PF13851.6 OWF40432.1 - 0.013 14.8 7.5 0.024 14.0 7.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF5446 PF17522.2 OWF40432.1 - 0.015 15.4 1.6 6.3 7.0 0.5 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5446) DUF148 PF02520.17 OWF40432.1 - 0.023 14.8 2.3 0.023 14.8 2.3 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF148 AD PF09793.9 OWF40432.1 - 0.034 14.3 1.1 2.8 8.1 0.4 2.8 2 1 0 2 2 2 0 Anticodon-binding domain DUF883 PF05957.13 OWF40432.1 - 0.041 14.5 1.5 0.041 14.5 1.5 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 OWF40432.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 OWF40432.1 - 0.19 11.0 4.5 0.23 10.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 OWF40432.1 - 0.47 9.8 1.6 0.5 9.7 0.4 1.5 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF948 PF06103.11 OWF40432.1 - 0.59 10.4 3.6 2.4 8.5 2.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1043 PF06295.12 OWF40432.1 - 2.5 8.1 6.1 0.87 9.6 2.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Remorin_C PF03763.13 OWF40432.1 - 4.5 7.2 11.2 2.8 7.9 0.4 2.8 2 1 1 3 3 3 0 Remorin, C-terminal region LMBR1 PF04791.16 OWF40432.1 - 9.2 5.0 8.3 6.4 5.6 6.7 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein DDE_Tnp_1_6 PF13751.6 OWF40432.1 - 9.4 6.5 14.8 0.56 10.4 1.1 2.9 2 1 0 3 3 3 0 Transposase DDE domain Fer4 PF00037.27 OWF40433.1 - 2.7e-14 52.3 17.3 2.9e-08 33.2 4.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OWF40433.1 - 2.1e-12 47.4 10.9 2.1e-12 47.4 10.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OWF40433.1 - 1e-08 36.0 10.8 0.00036 21.4 1.6 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OWF40433.1 - 1.1e-08 35.0 9.4 0.00014 22.0 0.6 2.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OWF40433.1 - 2.5e-08 34.0 10.4 2.5e-08 34.0 10.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Roc PF08477.13 OWF40433.1 - 7.7e-08 32.6 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Fer4_10 PF13237.6 OWF40433.1 - 1.2e-07 31.7 24.6 2.6e-06 27.4 12.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 OWF40433.1 - 3.2e-07 30.7 9.3 0.0024 18.3 4.3 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OWF40433.1 - 4.3e-07 29.7 17.7 0.00035 20.5 5.3 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 OWF40433.1 - 5.5e-07 29.3 12.6 0.0045 17.0 2.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Arf PF00025.21 OWF40433.1 - 8.9e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OWF40433.1 - 2.3e-05 24.1 0.0 4.5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Ras family Fer4_4 PF12800.7 OWF40433.1 - 4.8e-05 23.5 12.1 0.002 18.5 2.7 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OWF40433.1 - 0.0009 19.7 13.2 0.026 15.0 12.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 OWF40433.1 - 0.014 15.6 5.6 1.1 9.6 0.3 2.6 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OWF40433.1 - 0.021 15.0 9.0 2.2 8.5 1.1 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 OWF40433.1 - 0.03 14.9 14.3 1.1 9.9 2.6 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 OWF40433.1 - 0.11 13.5 17.4 0.56 11.3 4.1 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 OWF40433.1 - 0.88 9.7 5.7 2.9 8.1 0.6 2.4 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 OWF40433.1 - 3.5 8.5 16.1 2.4 9.1 1.0 3.0 2 1 2 4 4 4 0 4Fe-4S dicluster domain Lipase_GDSL_2 PF13472.6 OWF40434.1 - 0.00039 20.9 0.0 0.00042 20.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AviRa PF11599.8 OWF40434.1 - 0.02 14.4 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Acetyltransf_18 PF18014.1 OWF40435.1 - 6.8e-16 58.2 0.0 1.1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF40435.1 - 2.6e-07 30.9 0.0 0.0002 21.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF40435.1 - 5.8e-07 29.5 0.0 0.023 14.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF40435.1 - 0.02 15.3 0.0 0.38 11.2 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-B_box PF00643.24 OWF40436.1 - 8.7e-06 25.8 2.2 8.7e-06 25.8 2.2 2.0 2 0 0 2 2 2 1 B-box zinc finger Atg14 PF10186.9 OWF40438.1 - 9.4e-14 51.2 16.9 6.5e-13 48.5 16.9 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 OWF40438.1 - 0.00076 18.5 6.8 0.0019 17.1 6.8 1.7 1 1 0 1 1 1 1 Vacuolar protein sorting 38 DUF3037 PF11236.8 OWF40438.1 - 0.36 11.3 4.7 1 9.8 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) LAMTOR5 PF16672.5 OWF40439.1 - 0.032 14.1 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 TMEM208_SND2 PF05620.11 OWF40439.1 - 0.065 13.0 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Pkinase_Tyr PF07714.17 OWF40441.1 - 6.5e-83 278.0 0.0 8.8e-83 277.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF40441.1 - 3.1e-45 154.6 0.0 4.6e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF40441.1 - 1.4e-18 66.7 0.0 2.7e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain zf-C3HC4 PF00097.25 OWF40441.1 - 8.6e-09 35.1 9.6 1.8e-08 34.1 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF40441.1 - 1e-07 31.8 11.3 2.3e-07 30.7 11.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF40441.1 - 1.7e-07 31.4 10.3 4e-07 30.3 10.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF40441.1 - 8.8e-06 25.5 7.0 1.9e-05 24.4 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF40441.1 - 2.3e-05 24.2 9.0 4.9e-05 23.2 9.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF40441.1 - 4.1e-05 23.6 9.9 8.7e-05 22.6 9.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF40441.1 - 0.00061 19.6 11.1 0.0017 18.1 11.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF40441.1 - 0.099 12.5 9.6 0.29 11.0 9.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF40441.1 - 0.16 12.3 6.1 0.44 10.9 6.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-H2C2_2 PF13465.6 OWF40441.1 - 0.2 12.2 5.3 1.2 9.7 5.3 2.4 1 0 0 1 1 1 0 Zinc-finger double domain zf-ANAPC11 PF12861.7 OWF40441.1 - 0.34 11.0 2.5 0.69 10.0 1.9 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IF4E PF01652.18 OWF40442.1 - 2.4e-55 186.7 0.2 2.8e-55 186.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Med4 PF10018.9 OWF40443.1 - 9.5e-32 110.2 0.4 1.4e-31 109.7 0.4 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TPR_MLP1_2 PF07926.12 OWF40443.1 - 0.028 14.5 15.4 0.043 13.9 15.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 OWF40443.1 - 0.079 12.8 14.6 0.21 11.4 15.0 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Phage_GPO PF05929.11 OWF40443.1 - 0.088 12.4 8.6 0.098 12.3 7.9 1.3 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF641 PF04859.12 OWF40443.1 - 0.17 12.2 7.5 0.46 10.8 7.5 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Imm5 PF14423.6 OWF40443.1 - 0.45 10.7 5.1 0.62 10.3 5.1 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 ISG65-75 PF11727.8 OWF40443.1 - 0.74 9.0 8.1 1 8.5 8.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4407 PF14362.6 OWF40443.1 - 0.89 8.8 6.6 1.2 8.4 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OWF40443.1 - 1.9 7.5 16.2 2.6 7.1 16.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PH PF00169.29 OWF40444.1 - 2.7e-11 43.9 0.0 3.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF40444.1 - 0.00014 22.3 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OWF40444.1 - 0.12 12.7 0.0 0.76 10.1 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Surp PF01805.20 OWF40445.1 - 4.4e-18 65.0 1.2 6.3e-18 64.5 0.1 2.0 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.22 OWF40445.1 - 1.3e-13 50.6 0.0 3.5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 OWF40445.1 - 6.1e-10 39.1 4.8 6.1e-10 39.1 4.8 2.6 3 0 0 3 3 3 1 cwf21 domain CTD_bind PF04818.13 OWF40445.1 - 0.00062 20.5 0.2 0.0022 18.8 0.2 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 OWF40445.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif CTK3 PF12243.8 OWF40445.1 - 0.027 14.5 0.1 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 HlyD_3 PF13437.6 OWF40446.1 - 0.0036 18.0 0.3 46 4.8 0.0 4.1 1 1 4 5 5 5 1 HlyD family secretion protein ig PF00047.25 OWF40447.1 - 0.00075 19.6 8.0 0.0015 18.6 1.6 2.6 2 1 0 2 2 2 1 Immunoglobulin domain NS3_envE PF02723.14 OWF40447.1 - 0.009 16.1 1.0 0.009 16.1 1.0 2.3 2 0 0 2 2 2 1 Non-structural protein NS3/Small envelope protein E GT87 PF09594.10 OWF40447.1 - 0.081 12.6 1.0 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 87 DUF4983 PF16356.5 OWF40447.1 - 0.11 13.3 0.3 0.56 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4983) Rib_5-P_isom_A PF06026.14 OWF40448.1 - 1.6e-63 213.4 0.0 2.1e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 OWF40448.1 - 0.0054 16.7 0.3 0.02 14.9 0.2 1.9 1 1 1 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 OWF40448.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain zf-HIT PF04438.16 OWF40449.1 - 1.2e-09 37.8 12.4 1.2e-09 37.8 12.4 1.7 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 OWF40449.1 - 0.0044 16.8 0.1 0.0086 15.8 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 OWF40449.1 - 0.048 13.8 8.4 0.13 12.4 8.4 1.8 1 0 0 1 1 1 0 MYND finger HMG_box PF00505.19 OWF40449.1 - 0.096 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box IQ PF00612.27 OWF40450.1 - 5.1e-79 252.7 45.1 2e-05 24.0 0.1 17.3 17 0 0 17 17 17 17 IQ calmodulin-binding motif Yop-YscD_cpl PF16697.5 OWF40450.1 - 1.8e-23 82.7 2.4 7.9 6.9 0.0 14.7 7 3 8 15 15 15 5 Inner membrane component of T3SS, cytoplasmic domain RIIa PF02197.17 OWF40450.1 - 1.2e-11 44.1 0.2 2.2e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Pex19 PF04614.12 OWF40450.1 - 2.3e-09 37.4 9.4 2.3e-09 37.4 9.4 4.2 4 2 0 4 4 4 1 Pex19 protein family SUKH-3 PF14433.6 OWF40450.1 - 0.45 11.0 2.3 1e+02 3.3 0.6 5.0 4 2 1 5 5 5 0 SUKH-3 immunity protein E1_DerP2_DerF2 PF02221.15 OWF40450.1 - 1.1 9.6 9.5 2.2 8.7 0.1 4.9 5 2 2 7 7 7 0 ML domain Hus1 PF04005.12 OWF40450.1 - 6.9 5.7 6.8 21 4.1 1.1 4.2 3 1 0 3 3 3 0 Hus1-like protein FPN1 PF06963.12 OWF40451.1 - 1.8e-125 418.9 12.7 1.7e-64 218.1 0.5 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) DUF687 PF05095.12 OWF40451.1 - 0.026 13.0 1.5 0.045 12.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Ndc1_Nup PF09531.10 OWF40451.1 - 1.7 7.2 5.7 0.92 8.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup EVI2A PF05399.11 OWF40451.1 - 5.2 6.6 9.0 11 5.5 9.0 1.6 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) 7tm_1 PF00001.21 OWF40452.1 - 3.3e-13 49.6 3.2 3.6e-13 49.4 3.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 OWF40452.1 - 8.7e-06 25.6 14.2 1.3e-05 25.0 14.2 1.2 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 OWF40452.1 - 0.00012 21.9 13.1 0.00019 21.2 13.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 OWF40452.1 - 0.00057 19.5 13.8 0.00057 19.5 13.8 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Serpentine_r_xa PF03383.15 OWF40452.1 - 0.092 12.7 5.9 0.16 11.9 5.3 1.7 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Mso1_Sec1_bdg PF14475.6 OWF40452.1 - 2.7 7.6 5.2 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 Sec1-binding region of Mso1 UFC1 PF08694.11 OWF40453.1 - 3.1e-86 286.7 0.1 3.5e-86 286.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 OWF40453.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF40453.1 - 0.05 13.9 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain SLATT_5 PF18160.1 OWF40453.1 - 0.12 11.7 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 CHCH PF06747.13 OWF40454.1 - 4.3e-05 23.5 3.5 4.3e-05 23.5 3.5 1.8 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 OWF40454.1 - 0.00037 20.5 1.4 0.0008 19.4 1.4 1.7 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GCK PF07802.11 OWF40454.1 - 0.0016 18.8 4.5 0.0027 18.1 4.5 1.5 1 0 0 1 1 1 1 GCK domain Lectin_C PF00059.21 OWF40455.1 - 2.7e-17 63.5 1.0 3.3e-17 63.2 1.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain SpoVAB PF13782.6 OWF40456.1 - 0.039 14.2 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Stage V sporulation protein AB Pterin_4a PF01329.19 OWF40457.1 - 5.5e-32 109.8 0.0 6.8e-32 109.5 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ABC_tran PF00005.27 OWF40458.1 - 1.1e-28 100.4 0.0 1.8e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OWF40458.1 - 6.9e-27 94.2 23.7 6.9e-27 94.2 23.7 2.3 2 1 0 2 2 2 1 ABC-2 type transporter SMC_N PF02463.19 OWF40458.1 - 1.1e-06 28.3 0.1 1.2e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OWF40458.1 - 1.7e-05 24.8 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 OWF40458.1 - 5.6e-05 23.1 0.1 0.34 10.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF40458.1 - 0.0055 17.2 0.5 0.012 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF40458.1 - 0.012 15.3 0.2 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OWF40458.1 - 0.02 15.4 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OWF40458.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OWF40458.1 - 0.033 14.6 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF3546 PF12066.8 OWF40459.1 - 0.065 13.4 1.6 0.16 12.2 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) His_Phos_2 PF00328.22 OWF40461.1 - 3.2e-26 92.6 0.0 1.5e-24 87.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Asn_synthase PF00733.21 OWF40462.1 - 2.3e-85 287.4 0.7 4.2e-53 181.3 0.1 2.0 1 1 1 2 2 2 2 Asparagine synthase NAD_synthase PF02540.17 OWF40462.1 - 0.0068 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 OWF40462.1 - 0.034 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OWF40462.1 - 0.078 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.21 OWF40463.1 - 1.3e-82 278.3 0.2 6.4e-51 174.1 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OWF40463.1 - 1.1e-28 99.6 0.0 2.3e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OWF40463.1 - 1.7e-22 80.0 0.0 4.2e-22 78.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OWF40463.1 - 0.00068 19.2 0.0 0.0025 17.3 0.0 1.8 1 1 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 OWF40463.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 OWF40463.1 - 0.021 13.9 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 OWF40463.1 - 0.068 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.21 OWF40464.1 - 2e-70 238.2 0.2 3.2e-44 152.0 0.2 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OWF40464.1 - 4.7e-29 100.8 0.0 8.1e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OWF40464.1 - 7.4e-23 81.2 0.0 2.1e-22 79.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OWF40464.1 - 1.4e-05 24.6 0.0 3.3e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 OWF40464.1 - 0.0046 16.1 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 NAD synthase UPF0242 PF06785.11 OWF40466.1 - 0.00074 19.7 2.7 0.0012 19.0 2.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus MAD PF05557.13 OWF40466.1 - 0.00098 17.6 9.0 0.0013 17.2 9.0 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Mac PF12464.8 OWF40466.1 - 0.049 13.9 0.5 0.13 12.5 0.5 1.7 1 0 0 1 1 1 0 Maltose acetyltransferase Spc7 PF08317.11 OWF40466.1 - 0.056 12.3 12.6 0.076 11.9 12.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 OWF40466.1 - 0.091 13.3 11.0 0.16 12.5 11.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 OWF40466.1 - 0.13 11.8 9.8 0.18 11.4 9.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FAM184 PF15665.5 OWF40466.1 - 0.18 11.6 12.8 0.47 10.2 12.8 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 OWF40466.1 - 0.93 9.6 15.8 2.1 8.4 15.8 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Antigen_Bd37 PF11641.8 OWF40466.1 - 1.1 8.8 6.4 1.2 8.6 5.1 1.6 1 1 1 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein FapA PF03961.13 OWF40466.1 - 1.1 7.8 4.7 1.3 7.5 4.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phlebovirus_NSM PF07246.11 OWF40466.1 - 1.1 8.6 5.9 1.8 7.9 5.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Exonuc_VII_L PF02601.15 OWF40466.1 - 2.4 7.6 6.7 3.1 7.3 6.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 OWF40466.1 - 2.4 6.0 8.2 3 5.6 8.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 OWF40466.1 - 2.7 8.0 14.6 1.7 8.6 0.5 2.7 1 1 1 2 2 2 0 Prefoldin subunit YabA PF06156.13 OWF40466.1 - 5.4 7.7 9.7 3.6 8.3 7.2 1.9 1 1 1 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 OWF40466.1 - 8.6 6.7 11.5 23 5.3 11.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Nucleos_tra2_C PF07662.13 OWF40467.1 - 8.6e-80 267.5 3.7 8.6e-80 267.5 3.7 2.1 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF40467.1 - 7.1e-25 87.4 1.0 3.7e-24 85.1 1.0 2.2 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OWF40467.1 - 2.1e-06 27.9 4.8 2.1e-06 27.9 4.8 3.9 3 1 1 4 4 4 1 Nucleoside recognition Spo7 PF03907.13 OWF40467.1 - 0.19 11.2 0.7 0.49 9.8 0.7 1.7 1 0 0 1 1 1 0 Spo7-like protein Vma12 PF11712.8 OWF40467.1 - 2.7 8.1 4.8 25 4.9 4.8 2.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Spaetzle PF16077.5 OWF40468.1 - 0.019 15.5 1.2 0.05 14.1 1.2 1.8 1 0 0 1 1 1 0 Spaetzle Mucin2_WxxW PF13330.6 OWF40469.1 - 9.2e-265 856.5 152.9 7.2e-21 74.8 2.1 19.6 19 0 0 19 19 19 17 Mucin-2 protein WxxW repeating region F5_F8_type_C PF00754.25 OWF40469.1 - 5.3e-158 517.9 18.6 1.1e-26 93.5 0.1 7.5 7 0 0 7 7 7 7 F5/8 type C domain VWD PF00094.25 OWF40469.1 - 2.2e-96 320.5 12.5 5e-32 111.4 0.7 3.5 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 OWF40469.1 - 3e-38 130.1 46.5 2.4e-16 59.9 9.8 8.9 9 0 0 9 9 9 3 C8 domain TIL PF01826.17 OWF40469.1 - 3e-17 62.6 97.4 2.7e-10 40.3 20.0 21.7 24 1 0 24 24 24 5 Trypsin Inhibitor like cysteine rich domain Ldl_recept_a PF00057.18 OWF40469.1 - 6.2e-06 26.3 7.6 6.2e-06 26.3 7.6 8.8 9 0 0 9 9 9 1 Low-density lipoprotein receptor domain class A VWC PF00093.18 OWF40469.1 - 0.00022 21.4 34.1 0.00064 20.0 10.3 20.1 15 6 2 17 17 17 5 von Willebrand factor type C domain Pacifastin_I PF05375.13 OWF40469.1 - 0.00048 19.8 13.5 0.00048 19.8 13.5 11.1 11 0 0 11 11 11 2 Pacifastin inhibitor (LCMII) DASH_Ask1 PF08655.10 OWF40469.1 - 0.055 13.4 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Ask1 CBM_3 PF00942.18 OWF40469.1 - 0.21 12.0 0.1 52 4.4 0.0 4.3 6 0 0 6 6 6 0 Cellulose binding domain PTS_2-RNA PF01885.16 OWF40471.1 - 3.6e-21 76.0 0.1 4.5e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family SLATT_4 PF18186.1 OWF40473.1 - 0.019 14.6 3.8 8.6 6.0 0.2 3.3 2 1 3 5 5 5 0 SMODS and SLOG-associating 2TM effector domain family 4 Chon_Sulph_att PF06566.11 OWF40473.1 - 0.87 9.4 12.1 14 5.5 12.0 2.0 1 1 0 1 1 1 0 Chondroitin sulphate attachment domain DUF5399 PF17377.2 OWF40474.1 - 0.18 11.6 0.1 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5399) Rsbr_N PF08678.10 OWF40475.1 - 0.04 14.0 0.1 0.81 9.8 0.1 2.0 1 1 0 1 1 1 0 Rsbr N terminal DUF92 PF01940.16 OWF40476.1 - 3.8e-74 249.1 5.6 6.1e-74 248.4 5.6 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF92 AgrB PF04647.15 OWF40476.1 - 0.0017 17.7 2.6 0.0017 17.7 2.6 1.8 2 0 0 2 2 2 1 Accessory gene regulator B Avl9 PF09794.9 OWF40478.1 - 3.8e-126 420.8 1.2 6.5e-125 416.8 1.2 2.1 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 OWF40478.1 - 1.7e-09 37.6 0.3 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 OWF40478.1 - 3.7e-09 36.6 0.9 0.00024 20.8 0.0 3.3 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 OWF40478.1 - 8e-08 32.8 0.0 8e-08 32.8 0.0 3.6 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 OWF40478.1 - 0.0012 18.8 1.1 1 9.3 0.0 2.8 2 1 1 3 3 3 2 DENN (AEX-3) domain Methyltransf_21 PF05050.12 OWF40479.1 - 9.6e-11 42.0 0.0 1.4e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain UDG PF03167.19 OWF40480.1 - 6.4e-24 84.7 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1180 PF06679.12 OWF40480.1 - 2 8.8 5.4 3.4 8.1 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-RING_5 PF14634.6 OWF40481.1 - 1.3e-07 31.5 11.1 1.3e-07 31.5 11.1 3.6 4 1 0 4 4 4 1 zinc-RING finger domain zf-B_box PF00643.24 OWF40481.1 - 9.8e-07 28.8 25.6 5.6e-06 26.4 6.1 4.6 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF40481.1 - 0.00021 21.1 12.9 0.00021 21.1 12.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Filamin PF00630.19 OWF40481.1 - 0.00025 21.8 0.2 0.0021 18.9 0.0 2.6 3 0 0 3 3 3 1 Filamin/ABP280 repeat zf-RING_2 PF13639.6 OWF40481.1 - 0.0032 17.8 10.7 0.0032 17.8 10.7 4.0 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF40481.1 - 0.0053 16.8 9.2 0.0053 16.8 9.2 2.8 3 0 0 3 3 3 1 RING-type zinc-finger Vps23_core PF09454.10 OWF40481.1 - 0.034 14.1 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 Vps23 core domain Spectrin PF00435.21 OWF40481.1 - 0.14 12.7 3.5 10 6.7 1.5 2.5 2 0 0 2 2 2 0 Spectrin repeat Mis14 PF08641.12 OWF40481.1 - 0.36 11.1 4.1 0.71 10.2 4.1 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Helicase_C PF00271.31 OWF40482.1 - 1e-18 67.7 0.1 1.1e-17 64.3 0.0 2.8 3 1 0 3 3 3 1 Helicase conserved C-terminal domain HTH_40 PF14493.6 OWF40482.1 - 4.3e-18 65.5 0.7 1.2e-17 64.1 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HRDC PF00570.23 OWF40482.1 - 3.4e-16 59.0 0.0 2.1e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 HRDC domain DEAD PF00270.29 OWF40482.1 - 4.5e-16 59.1 0.1 2e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 OWF40482.1 - 1e-15 57.5 0.0 3.8e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 OWF40482.1 - 2.8e-11 43.9 1.4 9.5e-11 42.3 1.0 2.2 2 0 0 2 2 2 1 RecQ zinc-binding Death PF00531.22 OWF40482.1 - 1.1e-09 38.4 0.7 3e-09 36.9 0.7 1.8 1 0 0 1 1 1 1 Death domain ResIII PF04851.15 OWF40482.1 - 7.7e-08 32.5 0.1 4.2e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma70_r4_2 PF08281.12 OWF40482.1 - 0.0072 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 DUF2757 PF10955.8 OWF40482.1 - 0.72 10.1 2.6 65 3.9 0.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) Guanylate_cyc PF00211.20 OWF40483.1 - 7.9e-116 384.1 0.1 3.5e-57 193.0 0.2 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 OWF40483.1 - 6.3e-89 299.0 2.4 4e-88 296.3 2.5 2.2 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 OWF40483.1 - 7.8e-14 52.1 0.1 2.2e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Chordopox_A13L PF05961.11 OWF40483.1 - 0.042 14.1 1.4 9.6 6.5 0.3 3.7 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF2439 PF10382.9 OWF40484.1 - 0.084 13.2 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) Sulfotransfer_2 PF03567.14 OWF40485.1 - 9e-33 114.2 0.2 1.1e-32 113.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family GCN5L1 PF06320.13 OWF40487.1 - 5.2e-47 158.7 8.6 6.4e-47 158.4 8.6 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) CDC73_N PF16050.5 OWF40487.1 - 0.037 13.4 2.1 0.044 13.1 2.1 1.1 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal AbiEi_2 PF09952.9 OWF40487.1 - 0.15 12.3 1.1 0.22 11.7 1.1 1.3 1 1 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system PGK PF00162.19 OWF40488.1 - 0.24 10.3 0.0 0.27 10.1 0.0 1.0 1 0 0 1 1 1 0 Phosphoglycerate kinase zf-C3HC4 PF00097.25 OWF40489.1 - 2e-06 27.5 10.9 2e-06 27.5 10.9 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF40489.1 - 0.00023 20.9 0.0 0.015 14.9 0.0 2.7 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 OWF40489.1 - 0.00077 19.6 24.0 0.0041 17.2 8.7 4.5 5 1 1 6 6 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF40489.1 - 0.00081 19.4 9.8 0.00081 19.4 9.8 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF40489.1 - 0.00089 19.5 10.3 0.00089 19.5 10.3 3.8 3 1 0 3 3 3 1 Ring finger domain NHL PF01436.21 OWF40489.1 - 0.0011 18.9 1.2 0.51 10.5 0.1 3.4 3 0 0 3 3 3 1 NHL repeat zf-RING_5 PF14634.6 OWF40489.1 - 0.0035 17.3 9.4 0.0035 17.3 9.4 3.3 3 0 0 3 3 2 1 zinc-RING finger domain SBBP PF06739.11 OWF40489.1 - 0.025 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Beta-propeller repeat Exonuc_VII_L PF02601.15 OWF40489.1 - 0.12 11.9 4.5 0.21 11.1 4.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5344 PF17279.2 OWF40489.1 - 0.15 12.6 2.4 1.8 9.2 0.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) YkuI_C PF10388.9 OWF40489.1 - 0.2 11.4 6.9 0.34 10.7 1.4 2.4 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain DUF948 PF06103.11 OWF40489.1 - 0.53 10.6 3.4 0.83 10.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 OWF40489.1 - 3.4 7.7 8.9 6.3 6.9 8.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4 PF00097.25 OWF40490.1 - 2.2e-06 27.4 11.3 2.2e-06 27.4 11.3 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF40490.1 - 0.00019 21.5 23.2 0.0019 18.3 6.5 4.4 5 1 0 5 5 4 2 B-box zinc finger SGL PF08450.12 OWF40490.1 - 0.00054 19.6 0.0 0.0062 16.1 0.0 2.5 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region zf-RING_2 PF13639.6 OWF40490.1 - 0.0012 19.2 10.6 0.0012 19.2 10.6 3.7 3 2 1 4 4 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF40490.1 - 0.0035 17.3 9.6 0.0035 17.3 9.6 3.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF40490.1 - 0.0071 16.3 11.8 0.0071 16.3 11.8 3.2 2 1 0 2 2 2 1 RING-type zinc-finger DUF5344 PF17279.2 OWF40490.1 - 0.018 15.6 2.6 6 7.5 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) SBBP PF06739.11 OWF40490.1 - 0.025 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Beta-propeller repeat DUF948 PF06103.11 OWF40490.1 - 0.15 12.3 3.8 0.16 12.2 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NHL PF01436.21 OWF40490.1 - 0.16 12.1 0.3 33 4.8 0.0 2.9 2 0 0 2 2 2 0 NHL repeat Jacalin PF01419.17 OWF40490.1 - 0.21 11.5 2.5 0.48 10.4 0.6 2.2 1 1 1 2 2 2 0 Jacalin-like lectin domain YkuI_C PF10388.9 OWF40490.1 - 0.45 10.3 6.8 0.3 10.9 1.4 2.3 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain Exonuc_VII_L PF02601.15 OWF40490.1 - 0.56 9.7 6.0 0.87 9.1 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 OWF40490.1 - 3.1 7.9 9.2 5.2 7.1 9.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cobl PF09469.10 OWF40491.1 - 5.9e-06 26.5 0.0 2.3e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 OWF40491.1 - 0.001 19.1 0.0 0.093 12.8 0.0 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain GFO_IDH_MocA PF01408.22 OWF40492.1 - 6.2e-17 62.5 0.2 8.8e-17 62.0 0.2 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OWF40492.1 - 1e-08 35.1 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 OWF40492.1 - 0.00022 21.5 0.1 0.00056 20.2 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 OWF40492.1 - 0.003 18.0 0.1 0.0052 17.2 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 OWF40492.1 - 0.0077 15.9 0.2 0.015 14.9 0.2 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA MGTL PF17059.5 OWF40493.1 - 1.6 8.6 5.3 21 5.1 0.0 4.0 3 0 0 3 3 3 0 MgtA leader peptide RPE65 PF03055.15 OWF40494.1 - 9.6e-83 278.9 3.8 1.1e-82 278.7 3.8 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Corona_6B_7B PF03262.13 OWF40494.1 - 0.023 14.2 0.0 1.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Coronavirus 6B/7B protein R3H PF01424.22 OWF40496.1 - 3.8e-17 62.0 0.1 8e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 OWF40496.1 - 2.3e-11 43.5 90.1 1e-05 25.5 11.5 13.6 14 1 1 15 15 15 7 NF-X1 type zinc finger DUF3793 PF12672.7 OWF40496.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF2340 PF10209.9 OWF40497.1 - 2.7e-42 144.0 0.1 3e-42 143.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Y_phosphatase PF00102.27 OWF40498.1 - 3.3e-79 265.8 0.2 5.2e-79 265.1 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 OWF40498.1 - 2.8e-26 91.7 0.4 1.3e-25 89.6 0.2 2.2 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 OWF40498.1 - 4.1e-24 85.2 0.3 2.4e-23 82.8 0.4 2.3 2 0 0 2 2 2 1 FERM central domain PDZ PF00595.24 OWF40498.1 - 1.3e-18 67.1 0.1 3e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain FERM_N PF09379.10 OWF40498.1 - 5.5e-15 55.0 0.1 3.3e-13 49.4 0.0 2.6 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 OWF40498.1 - 7.1e-14 51.6 9.1 1.7e-13 50.4 9.1 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) PDZ_6 PF17820.1 OWF40498.1 - 6.6e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase3 PF13350.6 OWF40498.1 - 0.0033 17.4 0.0 0.0091 16.0 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OWF40498.1 - 0.0088 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PDZ_2 PF13180.6 OWF40498.1 - 0.033 14.5 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Colipase-like PF15083.6 OWF40499.1 - 0.049 13.8 6.1 0.094 12.9 6.1 1.4 1 1 0 1 1 1 0 Colipase-like SNAPc_SNAP43 PF09808.9 OWF40500.1 - 1.3e-50 172.0 10.2 2.4e-50 171.1 10.2 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Herpes_DNAp_acc PF04929.12 OWF40500.1 - 0.043 12.8 4.3 0.064 12.2 4.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CbiG_C PF01890.16 OWF40500.1 - 0.13 12.8 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus Pkinase PF00069.25 OWF40501.1 - 1.5e-33 116.3 0.0 3.2e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40501.1 - 1.7e-12 47.2 0.0 3.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CEP63 PF17045.5 OWF40502.1 - 0.0052 16.7 0.9 0.0057 16.6 0.9 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa HD_4 PF13328.6 OWF40502.1 - 0.019 14.7 1.0 0.03 14.0 1.0 1.4 1 1 0 1 1 1 0 HD domain Csm1_N PF18504.1 OWF40502.1 - 0.032 14.6 2.7 2.2 8.7 0.4 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Med9 PF07544.13 OWF40502.1 - 0.036 14.2 1.0 0.59 10.3 1.0 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Phlebovirus_NSM PF07246.11 OWF40502.1 - 0.11 11.9 2.9 0.13 11.6 2.9 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PKcGMP_CC PF16808.5 OWF40502.1 - 0.19 11.6 4.2 4.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Apis_Csd PF11671.8 OWF40502.1 - 0.78 9.8 5.8 1 9.4 5.8 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Pkinase PF00069.25 OWF40503.1 - 3.9e-33 115.0 0.0 8e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40503.1 - 1e-11 44.6 0.0 2e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase ATG27 PF09451.10 OWF40504.1 - 5.6e-15 55.9 0.0 9.2e-15 55.2 0.0 1.2 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF40504.1 - 2.1e-10 40.2 0.2 3.8e-07 29.5 0.1 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate receptor Exo_endo_phos PF03372.23 OWF40506.1 - 2.6e-05 23.8 0.0 0.00022 20.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2649 PF10854.8 OWF40508.1 - 0.44 10.9 14.0 2.5 8.5 1.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF2649) VWD PF00094.25 OWF40508.1 - 2.2 8.5 5.3 17 5.6 0.5 2.3 1 1 1 2 2 2 0 von Willebrand factor type D domain EF-hand_1 PF00036.32 OWF40510.1 - 7.6e-14 50.2 7.3 0.00026 20.3 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF40510.1 - 3.7e-11 42.0 5.0 0.00041 20.0 0.3 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OWF40510.1 - 5.5e-10 39.6 16.2 2.8e-08 34.1 0.7 3.9 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 OWF40510.1 - 8.8e-10 38.3 5.7 0.00018 21.3 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF40510.1 - 6.7e-07 28.5 2.5 0.0013 18.2 0.0 3.8 4 0 0 4 4 4 2 EF hand Presenilin PF01080.17 OWF40510.1 - 0.025 13.4 17.6 0.032 13.0 17.6 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OWF40510.1 - 0.032 13.4 11.3 0.049 12.8 11.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Borrelia_P83 PF05262.11 OWF40510.1 - 0.032 12.7 26.0 0.037 12.5 26.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein EF-hand_9 PF14658.6 OWF40510.1 - 0.052 13.9 0.1 18 5.8 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain DUF2151 PF10221.9 OWF40510.1 - 0.35 9.4 17.1 0.53 8.8 17.1 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator Med12-LCEWAV PF12145.8 OWF40510.1 - 1 8.2 13.4 1.5 7.5 13.4 1.3 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Raftlin PF15250.6 OWF40510.1 - 1.2 7.8 19.2 1.7 7.3 19.2 1.2 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.13 OWF40510.1 - 1.5 7.5 22.2 2.3 6.9 22.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spore_coat_CotO PF14153.6 OWF40510.1 - 2.8 7.8 34.0 5.2 6.9 34.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO V_ATPase_I PF01496.19 OWF40510.1 - 4.4 5.1 17.5 7.6 4.3 17.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 OWF40510.1 - 4.6 7.2 21.9 1.5 8.7 19.1 1.7 2 0 0 2 2 2 0 Protein Family FAM60A NAM-associated PF14303.6 OWF40511.1 - 0.0087 16.8 4.4 0.0094 16.7 4.4 1.0 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Ribosomal_60s PF00428.19 OWF40511.1 - 0.0088 16.6 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein PI_PP_I PF18363.1 OWF40511.1 - 0.043 14.0 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain 7tm_2 PF00002.24 OWF40514.1 - 2.4e-59 200.6 14.3 3.2e-59 200.2 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF40514.1 - 7e-16 58.3 2.4 1.2e-15 57.5 2.4 1.4 1 0 0 1 1 1 1 Hormone receptor domain Pox_mRNA-cap PF03341.13 OWF40515.1 - 0.061 12.6 0.1 0.069 12.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit DDE_1 PF03184.19 OWF40517.1 - 8.5e-29 100.4 0.0 1.7e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 OWF40517.1 - 2.5e-10 39.9 0.0 4.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 OWF40517.1 - 3.6e-07 30.1 0.0 0.00055 19.7 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 OWF40517.1 - 0.00055 20.0 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 OWF40517.1 - 0.00056 19.9 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain cNMP_binding PF00027.29 OWF40518.1 - 8.8e-22 77.0 1.8 3.8e-13 49.3 0.4 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain FAINT PF04385.15 OWF40518.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function, DUF529 SapB_1 PF05184.15 OWF40518.1 - 0.12 12.4 0.1 0.56 10.3 0.1 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Pyr_redox_2 PF07992.14 OWF40519.1 - 3.6e-68 230.0 3.5 5e-68 229.5 3.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OWF40519.1 - 5.5e-34 116.7 0.5 1.3e-33 115.5 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 OWF40519.1 - 2e-21 76.6 0.3 2.8e-21 76.1 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF40519.1 - 7.8e-21 74.4 8.8 8e-20 71.2 0.6 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF40519.1 - 2.5e-07 30.4 1.5 1.1e-05 25.0 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OWF40519.1 - 0.00011 21.4 7.0 0.0016 17.6 5.0 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 OWF40519.1 - 0.00013 20.8 9.3 0.081 11.6 0.6 3.4 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OWF40519.1 - 0.00013 21.3 1.9 0.18 11.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 OWF40519.1 - 0.00019 21.6 0.3 0.0044 17.2 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OWF40519.1 - 0.00038 19.7 0.0 0.00077 18.7 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OWF40519.1 - 0.00088 18.5 3.7 0.0023 17.1 2.3 2.4 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OWF40519.1 - 0.0059 16.0 4.8 0.6 9.5 0.1 3.3 3 1 1 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OWF40519.1 - 0.025 15.0 0.4 9.7 6.7 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 OWF40519.1 - 0.19 11.6 4.4 3.1 7.7 0.2 3.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 OWF40519.1 - 1.2 8.7 15.0 0.019 14.6 2.6 3.1 2 2 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF40519.1 - 1.2 8.1 5.2 3 6.8 0.4 3.2 4 1 0 4 4 4 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OWF40519.1 - 2 7.6 7.3 1.2 8.3 0.5 2.6 2 1 1 3 3 3 0 FAD binding domain FKBP_N_2 PF18023.1 OWF40520.1 - 2.9e-08 33.8 3.3 1.8 8.7 0.0 6.5 1 1 5 7 7 7 3 BDBT FKBP like N-terminal STG PF15809.5 OWF40520.1 - 8.7e-06 26.0 0.0 13 5.8 0.0 4.8 1 1 4 6 6 6 2 Simian taste bud-specific gene product family DUF3055 PF11256.8 OWF40520.1 - 0.00053 20.2 4.0 12 6.2 0.0 4.8 1 1 4 6 6 6 2 Protein of unknown function (DUF3055) SRP1_TIP1 PF00660.17 OWF40520.1 - 0.0031 17.5 0.8 0.17 12.0 0.1 2.9 1 1 2 3 3 3 1 Seripauperin and TIP1 family MmlI PF09448.10 OWF40520.1 - 0.018 15.5 13.9 24 5.4 1.8 6.1 1 1 2 3 3 3 0 Methylmuconolactone methyl-isomerase Orn_Arg_deC_N PF02784.16 OWF40520.1 - 0.022 14.1 0.6 1.3 8.4 0.0 3.1 1 1 1 3 3 3 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain RuvX PF03652.15 OWF40520.1 - 0.062 13.7 0.7 1.1e+02 3.1 0.0 3.9 1 1 4 5 5 5 0 Holliday junction resolvase Tmemb_40 PF10160.9 OWF40520.1 - 0.52 9.7 8.3 1.9 7.9 1.0 3.6 1 1 4 5 5 5 0 Predicted membrane protein STG PF15809.5 OWF40521.1 - 4.4e-07 30.2 0.0 1.3 9.0 0.0 6.1 1 1 4 7 7 7 1 Simian taste bud-specific gene product family Baculo_PEP_C PF04513.12 OWF40521.1 - 2.2e-06 27.7 0.1 0.051 13.6 0.1 3.4 1 1 3 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus FKBP_N_2 PF18023.1 OWF40521.1 - 3.5e-06 27.1 2.2 6.9 6.8 0.1 7.2 1 1 4 6 6 6 1 BDBT FKBP like N-terminal DUF2652 PF10851.8 OWF40521.1 - 1e-05 25.6 11.0 8.5 6.5 0.1 5.9 5 1 2 7 7 7 3 Protein of unknown function (DUF2652) ANAPC4 PF12896.7 OWF40521.1 - 4.5e-05 23.1 0.4 6.5 6.2 0.0 4.9 1 1 4 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 4 LXG PF04740.12 OWF40521.1 - 0.00047 19.9 0.0 3.1 7.4 0.0 3.9 1 1 3 4 4 4 1 LXG domain of WXG superfamily Prominin PF05478.11 OWF40521.1 - 0.0044 15.1 0.4 0.45 8.4 0.1 2.3 1 1 1 2 2 2 2 Prominin zf-RNPHF PF08080.12 OWF40521.1 - 0.0062 16.5 0.7 2.6e+02 1.7 0.0 6.4 6 0 0 6 6 6 0 RNPHF zinc finger RP853 PF17542.2 OWF40521.1 - 0.0075 15.4 3.9 7.9 5.5 0.1 4.7 1 1 5 6 6 6 1 Uncharacterized RP853 DUF3375 PF11855.8 OWF40521.1 - 0.0076 15.2 0.0 9 5.1 0.0 3.3 1 1 3 4 4 4 1 Protein of unknown function (DUF3375) DUF3120 PF11318.8 OWF40521.1 - 0.041 14.2 1.3 6 7.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3120) DNTTIP1_dimer PF18192.1 OWF40521.1 - 0.063 13.6 8.7 4.5 7.7 0.8 6.1 1 1 4 5 5 5 0 DNTTIP1 dimerisation domain MmlI PF09448.10 OWF40521.1 - 0.077 13.5 23.9 82 3.7 0.5 7.7 1 1 3 4 4 4 0 Methylmuconolactone methyl-isomerase LRR_8 PF13855.6 OWF40522.1 - 3.9e-23 81.0 20.0 9.7e-07 28.5 4.1 5.8 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OWF40522.1 - 3.9e-19 68.4 21.6 1.1e-05 25.6 3.7 6.0 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) Roc PF08477.13 OWF40522.1 - 1.5e-14 54.3 0.2 6.5e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF40522.1 - 2.7e-11 43.7 0.5 6e-10 39.3 0.5 2.6 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 OWF40522.1 - 4.1e-08 33.0 1.8 7.7e-08 32.1 0.2 2.4 3 0 0 3 3 3 1 Ras family LRR_9 PF14580.6 OWF40522.1 - 0.0053 16.3 17.3 0.012 15.1 0.7 3.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 OWF40522.1 - 0.0071 16.7 14.0 0.41 11.4 0.1 6.2 5 2 0 5 5 5 2 Leucine Rich Repeat GTP_EFTU PF00009.27 OWF40522.1 - 0.037 13.6 0.0 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OWF40522.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SopA PF13981.6 OWF40522.1 - 0.087 13.3 0.3 2.3 8.6 0.0 3.2 3 0 0 3 3 3 0 SopA-like central domain ABC_tran PF00005.27 OWF40522.1 - 0.13 12.7 0.1 0.72 10.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter LRR_6 PF13516.6 OWF40522.1 - 0.57 10.4 28.0 0.3 11.3 0.2 7.6 9 1 0 9 9 8 0 Leucine Rich repeat DUF5368 PF17336.2 OWF40523.1 - 0.064 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5368) TLD PF07534.16 OWF40524.1 - 1.1e-30 106.7 1.5 1.5e-30 106.2 0.2 2.0 2 0 0 2 2 2 1 TLD RabGAP-TBC PF00566.18 OWF40524.1 - 8.4e-19 68.1 0.3 1.8e-18 67.0 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MbeD_MobD PF04899.12 OWF40525.1 - 0.0012 18.9 1.1 0.0061 16.7 1.1 2.1 1 0 0 1 1 1 1 MbeD/MobD like Methyltransf_25 PF13649.6 OWF40525.1 - 0.0025 18.5 0.0 0.46 11.2 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain bZIP_1 PF00170.21 OWF40525.1 - 0.05 13.7 0.6 0.05 13.7 0.6 2.5 2 1 1 3 3 3 0 bZIP transcription factor Tubulin-binding PF00418.19 OWF40525.1 - 0.056 13.5 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat Imm7 PF15585.6 OWF40525.1 - 0.065 13.5 0.2 0.26 11.6 0.2 2.1 1 0 0 1 1 1 0 Immunity protein 7 Adeno_PIX PF03955.14 OWF40525.1 - 0.12 12.5 1.2 16 5.7 0.0 2.8 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) WGR PF05406.15 OWF40525.1 - 0.14 12.2 0.3 28 4.8 0.0 2.5 2 0 0 2 2 2 0 WGR domain FlaC_arch PF05377.11 OWF40525.1 - 0.17 12.3 2.7 0.33 11.4 0.7 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) USP8_interact PF08941.10 OWF40525.1 - 0.34 10.7 23.3 0.17 11.7 2.0 3.2 2 1 1 3 3 3 0 USP8 interacting Elf4 PF07011.11 OWF40525.1 - 2.4 8.1 26.9 7.8 6.5 6.6 3.7 1 1 3 4 4 4 0 Early Flowering 4 domain CLZ PF16526.5 OWF40525.1 - 6.8 7.1 8.1 16 5.9 0.3 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ENT PF03735.14 OWF40525.1 - 7.4 6.7 9.3 59 3.8 0.7 3.6 1 1 3 4 4 4 0 ENT domain RFX_DNA_binding PF02257.15 OWF40526.1 - 1.4e-27 96.1 0.5 3.3e-27 94.9 0.5 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TNF PF00229.18 OWF40527.1 - 1.7e-07 31.3 0.0 4.9e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family SusF_SusE PF16411.5 OWF40527.1 - 0.00083 19.9 0.0 0.00083 19.9 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein SusF_SusE Collagen PF01391.18 OWF40528.1 - 1.8e-07 30.8 36.1 7.4e-07 28.8 34.7 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNF PF00229.18 OWF40528.1 - 4.1e-07 30.0 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Imm25 PF15564.6 OWF40528.1 - 0.077 12.9 0.2 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 25 SusF_SusE PF16411.5 OWF40528.1 - 0.082 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein SusF_SusE Defensin_like PF10868.8 OWF40528.1 - 5.9 7.7 7.8 3.5 8.5 1.7 2.6 2 0 0 2 2 2 0 Cysteine-rich antifungal protein 2, defensin-like Collagen PF01391.18 OWF40529.1 - 1e-09 38.0 19.0 1.6e-09 37.4 19.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.18 OWF40529.1 - 0.0011 18.9 0.3 0.0029 17.5 0.3 1.7 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family bPH_5 PF10882.8 OWF40529.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain Collagen PF01391.18 OWF40530.1 - 8.8e-07 28.6 12.8 9.3e-07 28.5 10.8 2.0 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) VCX_VCY PF15231.6 OWF40530.1 - 1 10.0 7.4 1.8 9.2 7.4 1.3 1 0 0 1 1 1 0 Variable charge X/Y family TNF PF00229.18 OWF40531.1 - 1.7e-10 40.9 0.0 3.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF40531.1 - 0.00065 19.9 2.7 0.002 18.3 0.4 2.5 2 1 0 2 2 2 1 C1q domain TNF PF00229.18 OWF40532.1 - 8.3e-06 25.8 0.0 1.9e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family PAPA-1 PF04795.12 OWF40532.1 - 0.009 16.8 0.3 0.018 15.8 0.2 1.6 1 1 0 1 1 1 1 PAPA-1-like conserved region Mucin2_WxxW PF13330.6 OWF40533.1 - 2.9e-11 44.0 1.6 5.6e-11 43.1 1.6 1.5 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region zf-C2H2 PF00096.26 OWF40534.1 - 7.8e-16 57.6 27.6 6.4e-05 23.2 4.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF40534.1 - 3.1e-14 52.4 20.3 1.9e-06 27.5 2.7 4.4 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OWF40534.1 - 8e-09 35.5 24.1 5.8e-06 26.5 0.3 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF40534.1 - 7.2e-08 32.6 27.2 0.005 17.6 3.4 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 OWF40534.1 - 1.2e-05 25.5 12.8 0.0061 16.8 4.7 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.12 OWF40534.1 - 0.097 12.9 5.0 2.5 8.3 0.5 2.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.7 OWF40534.1 - 0.97 9.9 15.3 2.3 8.7 1.8 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 OWF40534.1 - 1 9.0 12.4 0.77 9.5 0.1 3.2 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 OWF40534.1 - 1.6 9.2 10.7 0.45 11.0 1.2 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 OWF40534.1 - 1.8 9.0 8.9 55 4.2 0.9 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 OWF40534.1 - 5.5 7.0 16.3 0.1 12.5 1.4 3.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type OrsD PF12013.8 OWF40534.1 - 8.8 6.8 18.7 5.7 7.4 2.8 4.1 2 2 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3458 PF11940.8 OWF40535.1 - 7.8e-66 218.6 167.2 2.5 8.6 0.4 45.6 1 1 43 44 44 44 43 Domain of unknown function (DUF3458) Ig-like fold MgtE_N PF03448.17 OWF40535.1 - 8.9e-25 87.3 236.2 7.4 7.2 1.5 32.6 1 1 3 12 12 12 12 MgtE intracellular N domain zf-H2C2_5 PF13909.6 OWF40536.1 - 5.4e-15 54.8 24.3 1.2e-07 31.3 1.4 5.1 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF40536.1 - 3.5e-14 52.4 35.0 3e-05 24.2 1.3 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF40536.1 - 4.5e-08 33.3 28.2 0.0093 16.7 0.6 4.9 5 0 0 5 5 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF40536.1 - 7.9e-07 29.2 0.4 7.9e-07 29.2 0.4 5.9 6 0 0 6 6 5 2 Zinc-finger double domain zf-Di19 PF05605.12 OWF40536.1 - 1.1e-05 25.6 14.8 0.00021 21.5 4.2 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OWF40536.1 - 0.0033 17.8 11.8 1.4 9.4 0.4 5.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OWF40536.1 - 0.064 13.0 21.1 0.16 11.8 0.7 4.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-MYST PF17772.1 OWF40536.1 - 0.22 11.2 4.5 3.8 7.2 0.3 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 OWF40536.1 - 0.3 11.4 8.7 21 5.6 0.0 3.9 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 OWF40536.1 - 0.4 10.7 6.8 0.22 11.6 0.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF1390 PF07150.11 OWF40536.1 - 0.71 9.5 5.6 2.4 7.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1390) zf-C2HE PF16278.5 OWF40536.1 - 1.9 9.0 9.0 0.26 11.8 1.4 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2225 PF09986.9 OWF40536.1 - 3 7.5 6.9 2.5 7.7 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 OWF40536.1 - 4.4 7.2 7.4 5.2 7.0 0.1 2.9 3 1 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 OWF40536.1 - 6.6 6.5 12.8 1.5 8.5 0.1 3.3 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain PP2C PF00481.21 OWF40537.1 - 9e-59 199.2 0.0 1.1e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OWF40537.1 - 4.1e-07 29.9 0.0 1.3e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Lipoprotein_2 PF00921.17 OWF40537.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein ARGLU PF15346.6 OWF40538.1 - 3.6e-50 169.7 62.9 3.6e-50 169.7 62.9 2.8 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Sulfotransfer_1 PF00685.27 OWF40539.1 - 2.8e-07 30.3 0.3 5.3e-06 26.1 0.3 2.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF40539.1 - 0.0042 17.5 0.7 0.021 15.2 0.2 2.5 2 1 0 2 2 2 1 Sulfotransferase family DUF347 PF03988.12 OWF40539.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Neurexophilin PF06312.12 OWF40542.1 - 9.1e-07 28.5 0.6 1.6e-06 27.8 0.6 1.3 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF40542.1 - 0.0003 21.6 0.2 0.00099 19.9 0.0 2.0 2 0 0 2 2 2 1 Filamin/ABP280 repeat RNase_T PF00929.24 OWF40543.1 - 2.4e-06 28.2 0.0 6.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 OWF40543.1 - 3.5e-05 23.8 0.2 0.0024 17.9 0.2 2.6 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo1 PF03104.19 OWF40543.1 - 0.00015 21.0 0.3 0.00035 19.8 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF5051 PF16473.5 OWF40543.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like DASH_Duo1 PF08651.10 OWF40543.1 - 0.21 11.4 1.0 0.48 10.2 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 Neurexophilin PF06312.12 OWF40544.1 - 4.9e-08 32.7 0.3 9.6e-08 31.7 0.3 1.4 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF40544.1 - 0.00028 21.7 0.0 0.00058 20.7 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Invasin_D3 PF09134.10 OWF40544.1 - 0.13 12.6 0.2 0.26 11.6 0.2 1.4 1 0 0 1 1 1 0 Invasin, domain 3 Cornifin PF02389.15 OWF40545.1 - 3.5e-55 185.9 0.0 0.082 13.1 0.0 15.5 1 1 18 20 20 20 20 Cornifin (SPRR) family Cornifin PF02389.15 OWF40546.1 - 6.1e-08 33.0 0.0 0.0022 18.2 0.0 2.3 1 1 1 2 2 2 2 Cornifin (SPRR) family L_protein_N PF15518.6 OWF40546.1 - 0.035 14.0 23.2 8.2 6.3 2.7 6.4 1 1 3 4 4 4 0 L protein N-terminus SURF2 PF05477.11 OWF40546.1 - 0.14 11.8 29.3 11 5.7 7.3 4.6 1 1 3 4 4 4 0 Surfeit locus protein 2 (SURF2) DUF4681 PF15732.5 OWF40546.1 - 2.8 8.2 15.7 1.8 8.8 1.0 3.3 2 1 3 5 5 5 0 Domain of unknown function (DUF4681) DUF3432 PF11914.8 OWF40547.1 - 0.00025 21.3 0.0 0.58 10.4 0.0 3.3 1 1 1 3 3 3 2 Domain of unknown function (DUF3432) YwcE PF17368.2 OWF40547.1 - 0.6 10.8 15.1 1.9 9.2 1.0 4.5 1 1 3 5 5 5 0 Spore morphogenesis and germination YwcE Cornifin PF02389.15 OWF40548.1 - 9.1e-05 22.7 0.0 0.0001 22.5 0.0 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.8 OWF40548.1 - 0.009 16.2 18.6 0.12 12.7 9.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) Cornifin PF02389.15 OWF40549.1 - 4.4e-06 26.9 0.0 4.7e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.8 OWF40549.1 - 0.041 14.1 12.7 0.1 12.9 12.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) PEPcase_2 PF14010.6 OWF40549.1 - 1 7.8 8.8 11 4.4 0.2 3.7 1 1 3 4 4 4 0 Phosphoenolpyruvate carboxylase Cornifin PF02389.15 OWF40550.1 - 4.4e-06 26.9 0.1 5.4e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.8 OWF40550.1 - 0.21 11.8 21.3 2.6 8.3 8.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) PEPcase_2 PF14010.6 OWF40550.1 - 4.3 5.7 6.6 14 4.0 0.6 3.2 1 1 2 3 3 3 0 Phosphoenolpyruvate carboxylase AMP-binding PF00501.28 OWF40551.1 - 1.2e-42 146.0 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF40551.1 - 1.1e-05 26.3 0.0 3.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2975 PF11188.8 OWF40552.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) TMEM206 PF15122.6 OWF40553.1 - 0.56 9.3 2.5 22 4.1 2.3 2.1 2 0 0 2 2 2 0 TMEM206 protein family ParBc PF02195.18 OWF40554.1 - 0.026 14.8 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 ParB-like nuclease domain TNF PF00229.18 OWF40555.1 - 5.9e-19 68.3 0.2 8.8e-19 67.7 0.2 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family 7TM_GPCR_Srj PF10319.9 OWF40555.1 - 0.24 10.7 2.6 0.48 9.7 0.4 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srj DUF4793 PF16041.5 OWF40556.1 - 6.4e-16 58.5 0.5 1.3e-15 57.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) DUF4792 PF16040.5 OWF40556.1 - 2e-07 30.8 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4792) DUF4793 PF16041.5 OWF40557.1 - 6.4e-10 39.1 1.5 1.4e-09 38.1 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) CYSTM PF12734.7 OWF40557.1 - 0.00083 19.6 13.9 0.0022 18.3 13.9 1.7 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Phage_holin_5_2 PF16079.5 OWF40557.1 - 1.7 9.1 6.3 2 8.8 1.4 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF4793 PF16041.5 OWF40558.1 - 6.1e-14 52.1 0.3 1.1e-13 51.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) DUF4792 PF16040.5 OWF40558.1 - 1.3e-06 28.2 0.0 3.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4792) Reovirus_L2 PF06016.11 OWF40558.1 - 0.057 10.6 0.1 0.083 10.1 0.1 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) LapA_dom PF06305.11 OWF40558.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4793 PF16041.5 OWF40559.1 - 2.9e-11 43.5 0.0 5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) DUF4792 PF16040.5 OWF40559.1 - 6.2e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4792) LRR_8 PF13855.6 OWF40560.1 - 2.8e-50 167.9 25.2 3.7e-17 61.8 1.9 6.6 4 2 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 OWF40560.1 - 5.6e-28 96.5 39.4 1.1e-06 28.8 1.4 8.3 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF40560.1 - 6.9e-18 64.8 1.2 1.3e-08 34.9 0.0 3.3 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF40560.1 - 1.4e-08 34.4 15.6 0.0004 19.9 1.5 4.8 1 1 4 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 OWF40560.1 - 2.2e-08 33.5 22.7 0.094 13.3 0.0 10.1 11 1 0 11 11 11 3 Leucine Rich Repeat LRRCT PF01463.24 OWF40560.1 - 0.00027 21.3 0.0 0.00067 20.0 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 OWF40560.1 - 0.014 15.4 27.9 0.17 12.0 0.2 7.6 9 0 0 9 9 9 0 Leucine Rich repeat RIFIN PF02009.16 OWF40560.1 - 0.24 11.3 1.0 0.37 10.6 1.0 1.2 1 0 0 1 1 1 0 Rifin Lig_chan PF00060.26 OWF40561.1 - 5.5e-22 78.2 0.3 5.9e-22 78.1 0.3 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OWF40561.1 - 1.8e-06 27.5 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ycf66_N PF07444.11 OWF40561.1 - 0.025 14.7 0.9 0.056 13.6 0.9 1.5 1 0 0 1 1 1 0 Ycf66 protein N-terminus TrkH PF02386.16 OWF40561.1 - 0.027 12.9 0.6 0.048 12.1 0.6 1.4 1 0 0 1 1 1 0 Cation transport protein FeoB_associated PF12669.7 OWF40561.1 - 0.29 11.5 3.2 0.78 10.2 0.4 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein CbiM PF01891.16 OWF40561.1 - 1.1 9.1 5.9 3.3 7.5 3.6 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region EBP PF05241.12 OWF40562.1 - 4.3e-63 212.0 5.6 5.3e-63 211.7 5.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF3792 PF12670.7 OWF40562.1 - 0.067 13.4 2.2 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Arm PF00514.23 OWF40563.1 - 9.8e-82 266.8 15.4 6.2e-13 48.3 0.1 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 OWF40563.1 - 1e-25 89.0 0.6 8e-24 83.0 1.6 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 OWF40563.1 - 2.1e-24 85.6 1.3 4.3e-08 33.5 0.1 6.2 4 2 2 6 6 6 5 HEAT-like repeat IBB PF01749.20 OWF40563.1 - 1e-22 80.4 2.4 2.9e-22 78.9 2.4 1.8 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 OWF40563.1 - 2.2e-20 72.8 0.2 4.6e-07 30.1 0.0 6.5 3 2 4 8 8 8 3 HEAT repeats HEAT PF02985.22 OWF40563.1 - 2.3e-19 67.8 3.0 0.0023 18.1 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.20 OWF40563.1 - 1.6e-10 40.2 0.0 4.5e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OWF40563.1 - 7.6e-07 29.3 0.1 0.84 9.7 0.0 3.9 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 OWF40563.1 - 3.6e-06 27.1 0.0 0.42 10.7 0.1 4.1 4 1 0 4 4 4 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 OWF40563.1 - 6.1e-06 26.2 0.1 1.5 8.9 0.0 4.2 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 OWF40563.1 - 2.4e-05 23.9 0.0 0.4 10.1 0.0 3.6 2 1 1 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.14 OWF40563.1 - 0.0007 19.0 0.0 0.018 14.3 0.0 2.8 1 1 1 2 2 2 1 V-ATPase subunit H DUF4042 PF13251.6 OWF40563.1 - 0.023 14.4 0.3 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) DRIM PF07539.12 OWF40563.1 - 0.038 12.3 0.1 5.6 5.1 0.0 2.5 2 0 0 2 2 2 0 Down-regulated in metastasis Mo25 PF08569.11 OWF40563.1 - 0.043 13.2 0.0 0.1 11.9 0.0 1.6 1 1 0 1 1 1 0 Mo25-like Inhibitor_I10 PF12559.8 OWF40563.1 - 0.077 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Serine endopeptidase inhibitors DCB PF16213.5 OWF40563.1 - 0.11 12.1 0.6 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF5564 PF17719.1 OWF40563.1 - 0.18 11.9 1.3 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5564) Sulfotransfer_2 PF03567.14 OWF40566.1 - 7.3e-24 85.1 0.1 8.9e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family DDE_Tnp_4 PF13359.6 OWF40567.1 - 2.7e-15 56.4 0.0 3.6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OWF40567.1 - 3.8e-08 33.3 0.0 6.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OWF40567.1 - 9.7e-05 22.7 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain partial_CstF PF15861.5 OWF40567.1 - 0.0051 16.6 0.8 0.0098 15.7 0.8 1.4 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain AAA_lid_8 PF17868.1 OWF40567.1 - 0.037 13.9 0.2 0.068 13.1 0.2 1.4 1 0 0 1 1 1 0 AAA lid domain DUF2746 PF10874.8 OWF40567.1 - 0.05 14.0 0.0 0.91 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) 7tm_1 PF00001.21 OWF40569.1 - 4e-28 98.5 17.0 5.1e-28 98.1 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3377 PF11857.8 OWF40569.1 - 0.48 10.4 6.8 1.9 8.5 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Synaptobrevin PF00957.21 OWF40569.1 - 7.1 6.5 0.0 2.8 7.8 1.1 3.6 4 0 0 4 4 4 0 Synaptobrevin TB2_DP1_HVA22 PF03134.19 OWF40570.1 - 0.074 13.0 3.2 1.5 8.8 0.1 3.4 2 1 1 3 3 3 0 TB2/DP1, HVA22 family Ribosomal_L2_C PF03947.18 OWF40570.1 - 0.24 11.6 0.1 57 3.9 0.0 3.3 2 1 0 4 4 4 0 Ribosomal Proteins L2, C-terminal domain VCBS PF13517.6 OWF40571.1 - 0.042 14.4 1.0 0.096 13.3 0.9 1.7 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Pox_L5 PF04872.13 OWF40571.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Poxvirus L5 protein family Porphyrn_cat_1 PF18206.1 OWF40571.1 - 0.11 13.2 0.1 0.16 12.6 0.1 1.2 1 0 0 1 1 1 0 Porphyranase catalytic subdomain 1 LRR_8 PF13855.6 OWF40572.1 - 1.3e-43 146.5 52.4 1.8e-09 37.2 0.3 9.1 4 3 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 OWF40572.1 - 1.3e-21 76.4 56.0 1.6e-07 31.5 1.2 11.0 5 2 8 13 13 13 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF40572.1 - 6.7e-16 58.4 0.0 1.1e-05 25.3 0.0 3.8 3 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF40572.1 - 2e-11 42.8 38.0 0.066 13.8 0.0 13.5 12 3 3 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.6 OWF40572.1 - 1.6e-06 27.8 19.2 0.011 15.3 0.8 5.2 3 2 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 OWF40572.1 - 0.00016 21.5 42.9 0.73 10.0 0.0 12.3 13 0 0 13 13 13 4 Leucine Rich repeat Pentapeptide_4 PF13599.6 OWF40572.1 - 0.073 13.3 3.4 1.7 8.9 0.1 3.9 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) COMM_domain PF07258.14 OWF40572.1 - 0.26 11.4 1.7 3 8.0 0.1 2.7 2 0 0 2 2 2 0 COMM domain GTP_EFTU PF00009.27 OWF40573.1 - 5e-45 153.4 0.0 7.6e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OWF40573.1 - 3e-32 111.2 0.0 7.4e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OWF40573.1 - 2.4e-11 43.8 0.3 7.8e-11 42.2 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF40573.1 - 1.9e-05 24.7 0.5 0.00082 19.4 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OWF40573.1 - 0.013 15.2 0.0 0.062 13.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 OWF40573.1 - 0.013 15.5 0.1 7.8 6.5 0.0 2.7 3 0 0 3 3 3 0 Dynamin family GTP_EFTU_D4 PF14578.6 OWF40573.1 - 0.016 15.1 0.4 0.068 13.1 0.4 2.1 1 0 0 1 1 1 0 Elongation factor Tu domain 4 G-alpha PF00503.20 OWF40573.1 - 0.043 13.0 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ATP_bind_1 PF03029.17 OWF40573.1 - 0.065 13.0 0.0 1.5 8.6 0.0 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OWF40573.1 - 0.14 11.9 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OWF40573.1 - 0.16 11.9 0.2 20 5.0 0.1 2.7 1 1 1 2 2 2 0 RsgA GTPase OpcA PF07239.11 OWF40574.1 - 0.036 13.8 0.6 0.075 12.7 0.5 1.5 1 1 0 1 1 1 0 Outer membrane protein OpcA Scramblase PF03803.15 OWF40575.1 - 1.5e-80 269.7 0.0 1.7e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Scramblase Med1 PF10744.9 OWF40575.1 - 0.023 13.7 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 LRR_8 PF13855.6 OWF40576.1 - 1.7e-11 43.7 1.0 9.2e-11 41.4 0.2 2.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_5 PF13306.6 OWF40576.1 - 1.4e-10 41.2 1.4 2.2e-05 24.4 0.1 2.6 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF40576.1 - 0.0014 18.9 0.2 0.0073 16.7 0.1 2.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) CBM_19 PF03427.13 OWF40576.1 - 0.14 12.2 0.3 0.14 12.2 0.3 4.4 4 1 0 4 4 4 0 Carbohydrate binding domain (family 19) VWA PF00092.28 OWF40577.1 - 3.1e-14 53.6 0.1 3.8e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWD PF00094.25 OWF40578.1 - 1.3e-12 48.2 1.4 3e-12 47.1 0.3 2.2 2 0 0 2 2 2 1 von Willebrand factor type D domain EGF_CA PF07645.15 OWF40578.1 - 4.3e-05 23.6 9.1 4.3e-05 23.6 9.1 4.6 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF PF00008.27 OWF40578.1 - 0.0035 17.6 6.2 0.0035 17.6 6.2 5.2 5 0 0 5 5 5 3 EGF-like domain NIDO PF06119.14 OWF40578.1 - 0.005 17.8 0.0 0.016 16.1 0.0 2.0 1 0 0 1 1 1 1 Nidogen-like EGF_2 PF07974.13 OWF40578.1 - 0.014 15.8 47.8 0.018 15.4 10.4 4.6 4 1 0 4 4 4 0 EGF-like domain zf-CCCH PF00642.24 OWF40578.1 - 3.3 7.7 8.5 0.22 11.5 1.1 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) hEGF PF12661.7 OWF40578.1 - 6.2 7.6 43.2 0.074 13.7 6.0 5.8 5 1 0 5 5 5 0 Human growth factor-like EGF Thyroglobulin_1 PF00086.18 OWF40579.1 - 2.6e-12 46.2 13.0 7e-09 35.2 2.2 3.3 3 1 1 4 4 4 2 Thyroglobulin type-1 repeat amfpi-1 PF12190.8 OWF40579.1 - 7.6 7.2 17.6 1 10.0 12.4 2.2 2 1 0 2 2 2 0 Fungal protease inhibitor WD40 PF00400.32 OWF40580.1 - 6e-34 115.5 14.2 6.3e-06 26.8 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF40580.1 - 3.3e-06 27.3 0.6 0.19 12.1 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OWF40580.1 - 0.0025 16.6 3.0 2.2 6.9 0.0 3.0 2 1 1 3 3 3 3 Nup133 N terminal like Nup160 PF11715.8 OWF40580.1 - 0.015 14.0 4.1 1.3 7.6 1.2 3.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DivIVA PF05103.13 OWF40580.1 - 0.14 12.3 0.7 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 DivIVA protein YgaB PF14182.6 OWF40580.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 YgaB-like protein A_deamin PF02137.18 OWF40581.1 - 1.2e-107 360.2 0.0 1.8e-107 359.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 OWF40581.1 - 5.6e-28 97.4 0.1 8.2e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif dsrm PF00035.26 OWF40582.1 - 2.2e-17 63.5 4.7 8.5e-08 32.8 0.1 2.8 3 0 0 3 3 3 2 Double-stranded RNA binding motif TbpB_B_D PF01298.18 OWF40582.1 - 0.0032 17.9 1.2 0.19 12.1 0.1 2.3 2 0 0 2 2 2 2 C-lobe and N-lobe beta barrels of Tf-binding protein B DnaG_DnaB_bind PF08278.11 OWF40583.1 - 0.0017 18.9 0.3 0.0028 18.2 0.3 1.4 1 1 0 1 1 1 1 DNA primase DnaG DnaB-binding DMRL_synthase PF00885.19 OWF40583.1 - 0.0066 16.3 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase YtxH PF12732.7 OWF40583.1 - 4.6 7.9 8.9 88 3.7 8.9 2.1 1 1 0 1 1 1 0 YtxH-like protein DTW PF03942.15 OWF40584.1 - 3.7e-38 131.2 0.0 1.1e-37 129.7 0.0 1.8 1 1 0 1 1 1 1 DTW domain zf-B_box PF00643.24 OWF40584.1 - 0.05 13.8 1.0 0.097 12.8 1.0 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-HIT PF04438.16 OWF40584.1 - 0.49 10.3 7.3 0.8 9.6 7.3 1.3 1 0 0 1 1 1 0 HIT zinc finger PNP_UDP_1 PF01048.20 OWF40585.1 - 2e-26 92.7 0.1 2.3e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 OWF40586.1 - 4.9e-15 55.9 0.5 4e-08 33.7 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF40586.1 - 1.8e-13 49.3 0.1 0.018 15.5 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OWF40586.1 - 8.7e-13 48.2 0.0 9e-07 29.1 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 OWF40586.1 - 4.6e-11 42.4 21.0 6.7e-11 41.9 21.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 OWF40586.1 - 9.6e-10 38.8 0.0 0.00034 21.1 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF40586.1 - 3.5e-08 33.5 0.0 0.44 11.1 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat PKD_channel PF08016.12 OWF40586.1 - 2e-07 30.1 8.1 3.5e-07 29.3 8.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel Bac_export_2 PF01312.19 OWF40586.1 - 7.3 5.7 8.8 8.5 5.5 7.3 1.9 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Ig_3 PF13927.6 OWF40587.1 - 2.9e-59 197.6 6.4 7.2e-13 49.0 0.1 7.0 7 0 0 7 7 6 6 Immunoglobulin domain I-set PF07679.16 OWF40587.1 - 3.4e-49 164.8 0.0 4.6e-11 42.6 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF40587.1 - 5.2e-43 145.3 4.5 2.9e-11 43.5 0.2 6.7 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 OWF40587.1 - 7.8e-35 118.9 1.0 3.7e-05 23.8 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 OWF40587.1 - 3.9e-26 91.2 6.1 2e-08 34.4 0.1 5.4 4 1 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 OWF40587.1 - 2.7e-12 46.8 9.4 0.036 14.2 0.0 8.5 6 3 1 7 7 7 3 Immunoglobulin V-set domain Lectin_C PF00059.21 OWF40587.1 - 1.6e-06 28.8 0.8 3.1e-06 27.9 0.8 1.5 1 0 0 1 1 1 1 Lectin C-type domain C2-set_2 PF08205.12 OWF40587.1 - 1.7e-05 24.8 0.2 1 9.4 0.0 4.7 5 1 1 6 6 6 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF40587.1 - 1.8e-05 25.1 2.2 0.34 11.3 0.0 5.0 6 1 0 6 6 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF40587.1 - 5.2e-05 22.7 2.0 0.74 9.4 0.0 5.6 6 0 0 6 6 6 1 Immunoglobulin domain Izumo-Ig PF16706.5 OWF40587.1 - 0.00026 21.0 0.2 6 7.0 0.0 5.0 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 OWF40587.1 - 0.0074 16.8 10.1 0.1 13.2 0.1 4.5 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 OWF40587.1 - 0.023 14.7 0.1 9.7 6.3 0.0 3.8 4 0 0 4 4 4 0 C17orf99 Ig domain YabP PF07873.11 OWF40587.1 - 0.032 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 YabP family UL45 PF05473.12 OWF40587.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like SnoaL_4 PF13577.6 OWF40587.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Receptor_2B4 PF11465.8 OWF40587.1 - 0.16 12.2 0.0 21 5.4 0.0 3.6 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 7tm_1 PF00001.21 OWF40588.1 - 3e-11 43.2 10.1 4.4e-11 42.6 10.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF40588.1 - 6.9e-08 32.2 7.0 6.9e-08 32.2 7.0 2.1 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cadherin PF00028.17 OWF40589.1 - 4.1e-126 411.8 59.7 2.1e-19 69.7 0.0 14.5 14 1 0 14 14 14 13 Cadherin domain Cadherin_2 PF08266.12 OWF40589.1 - 2.5e-08 33.6 0.4 0.021 14.6 0.0 7.0 8 0 0 8 8 8 1 Cadherin-like Cadherin_3 PF16184.5 OWF40589.1 - 3.1e-06 27.2 29.9 0.12 12.4 0.4 10.2 10 1 1 11 11 11 3 Cadherin-like MG1 PF17790.1 OWF40589.1 - 0.032 14.7 1.5 5.6 7.5 0.0 4.7 5 0 0 5 5 5 0 Macroglobulin domain MG1 cEGF PF12662.7 OWF40589.1 - 0.21 11.5 0.7 0.67 9.9 0.7 1.9 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 OWF40589.1 - 0.46 10.6 6.9 0.034 14.2 1.1 2.1 2 0 0 2 2 2 0 MSP1 EGF domain 1 Cadherin PF00028.17 OWF40590.1 - 3.7e-114 373.5 41.1 6.8e-19 68.1 0.1 13.6 13 0 0 13 13 13 11 Cadherin domain Cadherin_2 PF08266.12 OWF40590.1 - 1.5e-10 40.8 0.2 0.023 14.5 0.0 7.3 8 0 0 8 8 8 2 Cadherin-like EB PF01683.18 OWF40590.1 - 8.3e-09 35.6 61.3 0.00056 20.2 4.3 5.5 2 1 3 5 5 5 4 EB module Cadherin_3 PF16184.5 OWF40590.1 - 3.6e-06 26.9 31.8 0.91 9.6 1.0 10.3 11 0 0 11 11 11 3 Cadherin-like Cadherin_pro PF08758.11 OWF40590.1 - 0.0058 16.8 1.2 8.7 6.6 0.0 4.8 6 0 0 6 6 6 1 Cadherin prodomain like Orf78 PF06024.12 OWF40590.1 - 0.099 13.0 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) BRCT PF00533.26 OWF40591.1 - 8e-66 218.4 0.3 4.2e-11 43.1 0.0 7.9 8 0 0 8 8 8 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OWF40591.1 - 4e-62 206.1 7.5 6.9e-19 67.6 0.2 6.7 6 0 0 6 6 6 6 twin BRCT domain BRCT_2 PF16589.5 OWF40591.1 - 2.2e-31 108.1 0.4 2.8e-06 27.6 0.1 7.6 7 0 0 7 7 7 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OWF40591.1 - 2.1e-13 50.4 0.0 0.044 14.1 0.0 6.6 7 0 0 7 7 7 3 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OWF40591.1 - 3.3e-12 46.2 0.0 3.4e-05 23.6 0.0 6.0 7 0 0 7 7 7 2 Regulator of Ty1 transposition protein 107 BRCT domain HMG_box PF00505.19 OWF40592.1 - 6.1e-17 61.8 1.0 6.1e-17 61.8 1.0 3.0 3 0 0 3 3 2 1 HMG (high mobility group) box zf-H2C2_2 PF13465.6 OWF40592.1 - 1.4e-08 34.7 8.9 0.00015 22.0 5.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF40592.1 - 8.1e-07 29.2 16.9 0.002 18.5 6.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type HMG_box_2 PF09011.10 OWF40592.1 - 7.5e-06 26.4 0.3 7.5e-06 26.4 0.3 2.8 2 0 0 2 2 2 1 HMG-box domain zf-C2H2_4 PF13894.6 OWF40592.1 - 0.0068 17.1 14.5 0.52 11.3 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OWF40592.1 - 0.008 16.5 6.9 0.049 14.0 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 OWF40592.1 - 0.0086 15.7 4.7 1.9 8.1 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 OWF40592.1 - 0.2 12.0 3.9 8.3 6.8 1.6 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 OWF40592.1 - 0.41 10.8 3.9 5.3 7.2 0.4 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DUF1043 PF06295.12 OWF40592.1 - 1.9 8.5 15.1 9.1 6.3 15.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) LIM PF00412.22 OWF40592.1 - 2.1 8.7 6.6 5.4 7.3 6.6 1.8 1 0 0 1 1 1 0 LIM domain DUF1993 PF09351.10 OWF40592.1 - 6.9 6.8 7.8 0.46 10.6 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Zn_ribbon_recom PF13408.6 OWF40592.1 - 9.2 6.9 6.8 3 8.4 1.3 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain FAM183 PF14886.6 OWF40593.1 - 0.00059 20.5 0.3 0.00083 20.1 0.3 1.3 1 1 0 1 1 1 1 FAM183A and FAM183B related Cpn60_TCP1 PF00118.24 OWF40594.1 - 7.5e-157 522.9 5.1 9.2e-157 522.6 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PLDc PF00614.22 OWF40594.1 - 0.67 10.2 2.4 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif STAT_bind PF02864.15 OWF40595.1 - 7.1e-50 169.0 0.3 7.1e-50 169.0 0.3 2.4 2 1 1 3 3 3 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 OWF40595.1 - 4.1e-37 127.7 26.0 4.1e-37 127.7 26.0 2.8 3 1 0 3 3 3 1 STAT protein, all-alpha domain STAT_int PF02865.17 OWF40595.1 - 3.8e-35 121.0 4.3 3.8e-35 121.0 4.3 3.1 3 0 0 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.24 OWF40595.1 - 8.7e-11 41.8 0.0 8.1e-10 38.7 0.0 2.8 3 0 0 3 3 3 1 SH2 domain STAT_bind PF02864.15 OWF40596.1 - 4.9e-48 163.0 0.1 4.9e-48 163.0 0.1 2.7 2 1 1 3 3 3 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 OWF40596.1 - 4.1e-37 127.7 22.6 4.1e-37 127.7 22.6 2.8 2 1 0 2 2 2 1 STAT protein, all-alpha domain STAT_int PF02865.17 OWF40596.1 - 1.7e-35 122.1 5.3 1.7e-35 122.1 5.3 3.0 3 0 0 3 3 3 1 STAT protein, protein interaction domain SH2 PF00017.24 OWF40596.1 - 1.5e-10 41.0 0.0 7.4e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 SH2 domain T4_deiodinase PF00837.17 OWF40597.1 - 1.1e-52 178.6 0.0 1.4e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Neur_chan_LBD PF02931.23 OWF40598.1 - 3.5e-45 154.1 0.1 4.7e-45 153.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF40598.1 - 3.8e-11 43.5 13.9 3.8e-11 43.5 13.9 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Rdx PF10262.9 OWF40598.1 - 0.015 15.5 0.5 1.2 9.4 0.4 3.4 3 1 0 3 3 3 0 Rdx family TMEM169 PF15052.6 OWF40599.1 - 3.7e-48 163.0 7.1 4.7e-48 162.6 7.1 1.1 1 0 0 1 1 1 1 TMEM169 protein family Oleosin PF01277.17 OWF40599.1 - 1 9.2 6.1 4 7.2 0.2 2.3 2 0 0 2 2 2 0 Oleosin RabGAP-TBC PF00566.18 OWF40600.1 - 3.8e-26 92.1 7.9 3.8e-26 92.1 7.9 2.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain UPF0061 PF02696.14 OWF40601.1 - 5.9e-123 411.1 0.1 8e-122 407.4 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family tRNA-synt_1g PF09334.11 OWF40602.1 - 4.6e-152 506.3 0.9 6.1e-152 505.9 0.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 OWF40602.1 - 2.3e-30 104.5 19.0 7e-15 54.9 6.1 2.8 2 0 0 2 2 2 2 WHEP-TRS domain GST_N_5 PF18485.1 OWF40602.1 - 1.9e-17 63.4 0.1 5.5e-17 61.9 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain tRNA-synt_1 PF00133.22 OWF40602.1 - 1.5e-09 36.7 0.6 0.0011 17.4 0.0 3.3 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) GST_C_2 PF13410.6 OWF40602.1 - 0.00016 21.6 0.0 0.00044 20.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Anticodon_1 PF08264.13 OWF40602.1 - 0.00033 20.6 0.2 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA GST_C PF00043.25 OWF40602.1 - 0.0019 18.3 0.0 0.006 16.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 OWF40602.1 - 0.041 13.2 0.0 0.29 10.4 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zinc-ribbons_6 PF07191.12 OWF40602.1 - 3.4 7.7 6.0 9.5 6.3 6.0 1.8 1 0 0 1 1 1 0 zinc-ribbons zf-C2HC5 PF06221.13 OWF40602.1 - 4.5 7.4 5.7 1.2 9.2 0.9 2.1 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Mito_fiss_reg PF05308.11 OWF40602.1 - 6 6.9 9.4 1.2 9.1 3.0 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator bZIP_2 PF07716.15 OWF40604.1 - 3.7e-15 55.7 7.3 8e-15 54.7 7.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF40604.1 - 3.3e-05 23.9 8.0 5.9e-05 23.1 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Profilin PF00235.19 OWF40605.1 - 1.7e-12 47.7 0.0 1.9e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Profilin LPD25 PF18840.1 OWF40605.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 25 Vps16_N PF04841.13 OWF40606.1 - 2.8e-119 398.5 0.0 4.7e-119 397.8 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OWF40606.1 - 1.6e-101 339.5 8.6 2.4e-101 339.0 8.6 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 OWF40606.1 - 4.3e-05 23.7 0.1 0.71 10.2 0.0 3.9 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2839 PF10999.8 OWF40606.1 - 0.094 13.1 0.4 0.29 11.5 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) DUF269 PF03270.13 OWF40606.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF269 LRR_8 PF13855.6 OWF40607.1 - 6.9e-40 134.6 58.7 5.4e-14 51.7 7.1 9.1 6 3 3 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 OWF40607.1 - 6.3e-21 74.1 61.9 2.3e-07 31.0 1.4 12.0 4 2 7 13 13 13 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF40607.1 - 6e-10 38.9 16.7 0.0061 16.1 0.3 4.9 4 1 1 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 OWF40607.1 - 5.7e-09 36.0 15.0 0.00034 20.6 0.3 4.5 3 2 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF40607.1 - 9.6e-09 34.6 40.6 0.44 11.3 0.1 14.1 12 2 1 13 13 13 3 Leucine Rich Repeat TIR PF01582.20 OWF40607.1 - 1.4e-07 31.5 0.1 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF40607.1 - 4.7e-05 24.0 0.0 0.00048 20.7 0.0 2.3 2 0 0 2 2 2 1 TIR domain Plasmod_Pvs28 PF06247.11 OWF40607.1 - 4.7 7.6 6.5 7.1 7.0 1.3 3.2 2 1 0 2 2 2 0 Pvs28 EGF domain LRR_6 PF13516.6 OWF40607.1 - 8.8 6.7 67.3 0.26 11.5 1.1 11.9 15 0 0 15 15 15 0 Leucine Rich repeat LRR_8 PF13855.6 OWF40608.1 - 3.5e-38 129.2 55.5 4.2e-13 48.8 5.0 8.6 6 2 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OWF40608.1 - 1.2e-19 70.1 60.3 5.8e-05 23.4 2.4 11.4 5 2 5 12 12 12 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF40608.1 - 2.2e-09 37.0 17.3 0.0032 17.0 0.8 5.0 4 1 1 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 OWF40608.1 - 4.2e-09 36.4 15.2 0.00013 21.9 0.4 4.5 3 2 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) TIR PF01582.20 OWF40608.1 - 2.1e-07 30.9 0.1 4e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF40608.1 - 2.6e-07 30.3 40.8 0.44 11.3 0.1 13.7 12 3 0 12 12 12 2 Leucine Rich Repeat TIR_2 PF13676.6 OWF40608.1 - 4.2e-06 27.4 0.0 9.9e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 TIR domain MuF_C PF18819.1 OWF40608.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage MuF-C-terminal domain Plasmod_Pvs28 PF06247.11 OWF40608.1 - 3.5 8.0 6.2 6.3 7.2 1.1 3.2 2 1 0 2 2 2 0 Pvs28 EGF domain LRR_6 PF13516.6 OWF40608.1 - 9.3 6.6 63.4 0.16 12.1 1.1 11.3 14 0 0 14 14 14 0 Leucine Rich repeat Gly_transf_sug PF04488.15 OWF40609.1 - 2.5e-12 47.3 0.0 8e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OWF40609.1 - 0.00032 20.1 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 OWF40609.1 - 0.00048 19.6 0.2 0.00089 18.7 0.2 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein C1q PF00386.21 OWF40610.1 - 1.5e-27 96.4 0.1 1.5e-27 96.4 0.1 1.7 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF40610.1 - 3.8e-07 30.0 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 BclA C-terminal domain DUF1043 PF06295.12 OWF40610.1 - 2.5e-05 24.3 2.2 4e-05 23.6 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Jnk-SapK_ap_N PF09744.9 OWF40610.1 - 0.00048 20.4 3.0 0.00069 19.9 3.0 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Gp58 PF07902.11 OWF40610.1 - 0.00052 18.4 1.7 0.00069 18.0 1.7 1.1 1 0 0 1 1 1 1 gp58-like protein TPR_MLP1_2 PF07926.12 OWF40610.1 - 0.0017 18.4 3.4 0.0026 17.8 3.4 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4472 PF14739.6 OWF40610.1 - 0.0094 16.7 3.1 0.014 16.1 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) CLZ PF16526.5 OWF40610.1 - 0.012 15.9 3.7 0.021 15.1 3.0 1.8 2 0 0 2 2 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 OWF40610.1 - 0.013 15.6 3.7 0.018 15.1 3.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 OWF40610.1 - 0.022 13.6 3.0 0.029 13.3 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3573 PF12097.8 OWF40610.1 - 0.024 13.5 0.9 0.033 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FlaC_arch PF05377.11 OWF40610.1 - 0.027 14.9 1.3 0.059 13.8 0.8 1.8 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 OWF40610.1 - 0.031 14.1 1.7 0.044 13.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 OWF40610.1 - 0.043 14.0 1.8 4 7.7 3.1 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Streptin-Immun PF11083.8 OWF40610.1 - 0.071 13.5 0.9 0.19 12.2 0.9 1.8 1 1 0 1 1 1 0 Lantibiotic streptin immunity protein OmpH PF03938.14 OWF40610.1 - 0.083 13.2 2.8 0.13 12.6 2.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 OWF40610.1 - 0.12 12.7 4.9 0.34 11.2 4.9 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2096 PF09869.9 OWF40610.1 - 0.15 12.1 1.4 1.5 8.8 0.9 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Spectrin PF00435.21 OWF40610.1 - 0.21 12.1 3.5 0.49 10.9 3.5 1.5 1 1 0 1 1 1 0 Spectrin repeat MerR-DNA-bind PF09278.11 OWF40610.1 - 0.65 10.6 2.8 0.84 10.2 1.8 1.7 1 1 0 1 1 1 0 MerR, DNA binding EGF_2 PF07974.13 OWF40611.1 - 9e-20 70.7 174.6 0.0011 19.3 9.1 9.7 9 0 0 9 9 9 8 EGF-like domain hEGF PF12661.7 OWF40611.1 - 1.7e-14 53.8 126.8 0.0013 19.3 7.2 10.8 9 0 0 9 9 9 8 Human growth factor-like EGF EGF PF00008.27 OWF40611.1 - 5e-14 52.3 151.7 0.0028 17.9 10.7 9.8 9 0 0 9 9 9 8 EGF-like domain TSP_1 PF00090.19 OWF40611.1 - 4.9e-11 42.7 29.2 3.9e-07 30.2 11.7 6.3 6 1 0 6 6 6 2 Thrombospondin type 1 domain NtA PF03146.15 OWF40611.1 - 5.5e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Agrin NtA domain Laminin_G_3 PF13385.6 OWF40611.1 - 4.8e-06 26.8 0.0 8.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OWF40611.1 - 0.0025 18.4 0.0 0.0039 17.8 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain CLASP_N PF12348.8 OWF40612.1 - 6.2e-55 186.2 5.9 4.4e-35 121.3 0.2 5.0 5 0 0 5 5 5 2 CLASP N terminal HEAT PF02985.22 OWF40612.1 - 6.6e-20 69.5 5.2 0.00051 20.1 0.0 10.2 11 0 0 11 11 9 4 HEAT repeat Cnd1 PF12717.7 OWF40612.1 - 3.1e-14 53.3 14.9 0.019 15.0 0.2 7.3 7 2 1 8 8 7 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OWF40612.1 - 2e-11 44.4 5.3 1 10.0 0.0 6.8 6 0 0 6 6 6 5 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 OWF40612.1 - 1.2e-09 38.4 1.3 0.0025 18.2 0.0 6.5 5 1 3 8 8 8 2 HEAT repeats RTP1_C1 PF10363.9 OWF40612.1 - 6.5e-07 29.5 3.6 0.22 11.7 0.2 4.7 4 1 0 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OWF40612.1 - 7.6e-07 29.5 1.4 3.1 8.4 0.0 5.5 6 0 0 6 6 4 1 HEAT-like repeat Adaptin_N PF01602.20 OWF40612.1 - 1.7e-06 26.9 6.6 0.034 12.7 0.0 4.7 5 1 0 5 5 5 3 Adaptin N terminal region MMS19_C PF12460.8 OWF40612.1 - 0.00033 19.9 0.1 3.8 6.5 0.0 4.3 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal Tti2 PF10521.9 OWF40612.1 - 0.00062 19.4 0.6 2.7 7.4 0.0 4.1 4 0 0 4 4 4 1 Tti2 family TAN PF11640.8 OWF40612.1 - 0.017 15.3 0.2 0.21 11.7 0.0 2.9 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair RasGEF_N_2 PF14663.6 OWF40612.1 - 0.037 14.4 0.3 23 5.4 0.0 4.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Dopey_N PF04118.14 OWF40612.1 - 0.048 12.8 2.6 0.7 9.0 0.2 3.2 3 1 0 3 3 3 0 Dopey, N-terminal TFCD_C PF12612.8 OWF40612.1 - 0.11 12.3 0.3 2.6 7.8 0.1 3.3 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal MMS19_N PF14500.6 OWF40612.1 - 0.54 9.8 4.3 12 5.4 0.0 4.2 5 1 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Bax1-I PF01027.20 OWF40613.1 - 1.5e-45 155.6 32.6 1.7e-45 155.4 32.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 OWF40613.1 - 0.057 13.0 25.8 0.13 11.8 25.8 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like Hum_adeno_E3A PF05393.11 OWF40613.1 - 0.58 10.2 6.9 0.12 12.3 1.8 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Cytochrom_B_C PF00032.17 OWF40613.1 - 7.5 6.9 15.2 0.44 10.9 4.8 2.7 1 1 2 3 3 3 0 Cytochrome b(C-terminal)/b6/petD UCH PF00443.29 OWF40614.1 - 1.5e-37 129.5 2.7 6.8e-37 127.4 2.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF40614.1 - 3.4e-14 53.2 8.2 3.8e-10 39.9 5.1 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PID PF00640.23 OWF40615.1 - 3.4e-30 104.9 0.1 6.4e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 OWF40615.1 - 6.4e-12 45.8 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 OWF40615.1 - 9.1e-08 32.2 0.1 1.5e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) bZIP_1 PF00170.21 OWF40615.1 - 0.12 12.4 2.6 0.27 11.4 2.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OWF40615.1 - 0.14 12.3 5.6 0.27 11.3 5.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DDE_Tnp_IS1 PF03400.13 OWF40615.1 - 0.17 12.2 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 IS1 transposase CCD48 PF15799.5 OWF40615.1 - 0.31 9.3 2.9 0.31 9.3 1.5 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 48 SH3BP5 PF05276.14 OWF40616.1 - 9e-88 294.0 17.7 1.4e-87 293.4 17.7 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) LemA PF04011.12 OWF40616.1 - 0.6 9.9 5.1 0.49 10.3 2.0 2.2 2 0 0 2 2 2 0 LemA family Tropomyosin_1 PF12718.7 OWF40616.1 - 2.2 8.4 20.4 0.05 13.8 8.1 3.0 3 0 0 3 3 3 0 Tropomyosin like Seryl_tRNA_N PF02403.22 OWF40616.1 - 3.3 8.0 9.1 15 5.9 1.3 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Inhibitor_I53 PF11714.8 OWF40617.1 - 0.052 13.7 0.7 0.052 13.7 0.7 3.6 4 0 0 4 4 4 0 Thrombin inhibitor Madanin Bowman-Birk_leg PF00228.20 OWF40618.1 - 7.3e-21 74.3 43.7 9.6 6.7 0.0 15.4 16 0 0 16 16 16 14 Bowman-Birk serine protease inhibitor family 8TM_micro PF17028.5 OWF40618.1 - 1.7e-09 37.8 12.2 0.088 12.5 1.8 4.8 1 1 4 5 5 5 5 8TM Microsporidial transmembrane domain DUF2097 PF09870.9 OWF40618.1 - 6.8e-05 23.0 10.8 17 5.7 0.3 6.1 2 2 4 6 6 6 3 Uncharacterized protein conserved in archaea (DUF2097) YbaJ PF10757.9 OWF40618.1 - 0.00032 21.2 15.3 65 4.1 0.7 8.2 1 1 9 10 10 10 0 Biofilm formation regulator YbaJ zf-IS66 PF13005.7 OWF40618.1 - 0.04 14.3 15.2 62 4.1 0.1 6.3 1 1 8 10 10 10 0 zinc-finger binding domain of transposase IS66 Beta-prism_lec PF16458.5 OWF40618.1 - 0.22 11.5 0.2 1.2e+02 2.6 0.0 3.5 1 1 3 4 4 4 0 Beta-prism lectin Leu_zip PF15294.6 OWF40619.1 - 2.5e-98 329.0 21.1 2.8e-98 328.8 21.1 1.0 1 0 0 1 1 1 1 Leucine zipper Baseplate PF16774.5 OWF40619.1 - 0.0013 18.7 0.1 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 Baseplate protein Arf PF00025.21 OWF40619.1 - 0.033 13.6 0.7 0.076 12.5 0.7 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family V_ATPase_I PF01496.19 OWF40619.1 - 0.27 9.1 7.8 0.5 8.2 7.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.17 OWF40619.1 - 0.28 11.1 0.2 0.28 11.1 0.2 3.6 3 2 1 4 4 4 0 Prefoldin subunit DUF1664 PF07889.12 OWF40619.1 - 0.35 10.9 11.3 2 8.5 4.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OWF40619.1 - 1.5 8.8 5.0 1 9.4 0.8 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 OWF40619.1 - 3.2 7.9 12.5 0.89 9.6 1.6 3.7 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 OWF40619.1 - 4.9 7.5 9.9 40 4.6 1.3 4.1 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 OWF40619.1 - 5 7.8 12.8 17 6.1 0.6 4.1 4 0 0 4 4 4 0 SlyX Rx_N PF18052.1 OWF40619.1 - 6.7 7.1 12.0 3.7 7.9 5.3 3.5 2 2 0 2 2 2 0 Rx N-terminal domain RRM_1 PF00076.22 OWF40620.1 - 2.8e-14 52.7 0.0 5.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMSR PF01625.21 OWF40621.1 - 1e-64 217.4 2.7 1.2e-64 217.1 2.7 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PMSR PF01625.21 OWF40622.1 - 3.7e-65 218.8 4.9 4.5e-65 218.5 4.9 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4274 PF14096.6 OWF40622.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4274) Zip PF02535.22 OWF40623.1 - 1.1e-62 212.2 16.5 1.1e-62 212.2 16.5 2.7 2 1 0 2 2 2 1 ZIP Zinc transporter RRM_1 PF00076.22 OWF40624.1 - 1.2e-65 217.3 0.1 8.3e-22 76.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF40624.1 - 1.3e-11 44.1 0.0 0.00021 20.9 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF40624.1 - 0.00012 21.9 0.0 0.0015 18.3 0.0 2.6 2 1 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 OWF40624.1 - 0.0011 19.0 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 2 RNA binding motif Dsl1_N PF11988.8 OWF40624.1 - 0.012 14.6 1.0 0.013 14.5 0.2 1.4 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal Peptidase_M14 PF00246.24 OWF40625.1 - 4.1e-24 85.9 0.1 3.6e-23 82.8 0.1 2.3 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OWF40625.1 - 9e-13 48.5 0.1 1.6e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain MutS_V PF00488.21 OWF40626.1 - 2.7e-51 174.3 0.5 5.5e-51 173.3 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OWF40626.1 - 1.3e-29 103.8 1.0 3.5e-29 102.4 1.0 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OWF40626.1 - 5.7e-10 39.4 0.0 1.8e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV DUF4828 PF16110.5 OWF40626.1 - 0.033 14.7 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4828) AAA_14 PF13173.6 OWF40626.1 - 0.047 13.7 0.1 0.33 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Jun PF03957.13 OWF40627.1 - 1.1e-35 123.6 3.3 1.9e-34 119.6 3.3 2.6 1 1 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 OWF40627.1 - 8.5e-18 64.2 8.5 1.7e-17 63.2 8.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF40627.1 - 1.5e-07 31.3 8.8 8.1e-07 29.0 8.8 2.1 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF40627.1 - 5.5e-07 30.0 6.9 1.1e-06 29.1 6.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.9 OWF40627.1 - 0.022 15.0 1.3 0.022 15.0 1.3 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 OWF40627.1 - 0.058 12.7 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SOCS_box PF07525.16 OWF40628.1 - 2.7e-05 24.4 1.8 4.8e-05 23.6 1.8 1.5 1 0 0 1 1 1 1 SOCS box ANAPC4_WD40 PF12894.7 OWF40628.1 - 0.0022 18.3 0.0 8.2 6.8 0.0 3.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF40628.1 - 1.2 10.1 10.2 5.3 8.1 0.0 4.7 7 0 0 7 7 7 0 WD domain, G-beta repeat Methyltransf_23 PF13489.6 OWF40629.1 - 0.037 13.8 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Jun PF03957.13 OWF40630.1 - 3.1e-36 125.4 3.0 3.2e-35 122.1 3.0 2.4 1 1 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 OWF40630.1 - 7.9e-17 61.1 8.0 1.6e-16 60.1 8.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF40630.1 - 7.9e-07 29.5 4.9 1.5e-06 28.6 4.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OWF40630.1 - 1.6e-06 28.1 7.0 8.9e-06 25.7 7.0 2.1 1 1 0 1 1 1 1 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 OWF40630.1 - 0.011 15.9 1.4 0.026 14.8 1.4 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 OWF40630.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PspA_IM30 PF04012.12 OWF40630.1 - 0.066 12.8 0.9 0.13 11.8 0.9 1.5 1 0 0 1 1 1 0 PspA/IM30 family DUF3051 PF11252.8 OWF40630.1 - 0.14 11.8 0.2 0.3 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) SOCS_box PF07525.16 OWF40631.1 - 2.6e-05 24.5 1.8 4.8e-05 23.6 1.8 1.5 1 0 0 1 1 1 1 SOCS box ANAPC4_WD40 PF12894.7 OWF40631.1 - 0.0038 17.5 0.0 8.7 6.7 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF40631.1 - 3.4 8.7 11.4 5.3 8.1 0.0 4.6 7 0 0 7 7 7 0 WD domain, G-beta repeat Methyltransf_11 PF08241.12 OWF40632.1 - 1.2e-14 54.7 0.0 1.8e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF40632.1 - 1.2e-11 44.7 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF40632.1 - 7.3e-09 36.2 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF40632.1 - 1.2e-07 32.4 0.0 3.6e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF40632.1 - 7.6e-07 29.0 0.2 1.9e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF40632.1 - 0.00054 19.4 0.0 0.00083 18.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 OWF40632.1 - 0.0076 15.9 0.0 0.019 14.6 0.0 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 OWF40632.1 - 0.031 14.1 0.1 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Reprolysin_4 PF13583.6 OWF40633.1 - 1.6e-11 44.2 0.3 3.5e-11 43.1 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 OWF40633.1 - 1e-09 38.7 9.6 2.7e-09 37.4 9.6 1.8 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF40633.1 - 1.1e-09 38.7 1.3 7.3e-09 36.1 0.3 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin PF01421.19 OWF40633.1 - 3.2e-09 37.0 0.2 6.8e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 OWF40633.1 - 5.5e-09 36.2 0.3 1.5e-08 34.8 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF40633.1 - 7.3e-06 26.5 0.1 7.3e-06 26.5 0.1 2.8 4 0 0 4 4 4 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF40633.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Matrixin SMC_Nse1 PF07574.13 OWF40634.1 - 9.9e-28 97.4 1.1 9.2e-27 94.2 1.1 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 OWF40634.1 - 1.6e-07 31.5 14.9 1.6e-07 31.5 14.9 1.8 2 0 0 2 2 2 1 RING-like domain Zn_ribbon_17 PF17120.5 OWF40634.1 - 0.0091 15.6 9.3 0.0091 15.6 9.3 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type UCH PF00443.29 OWF40634.1 - 0.016 14.7 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase C1_2 PF03107.16 OWF40634.1 - 0.025 14.9 8.7 0.045 14.1 4.7 2.7 3 0 0 3 3 3 0 C1 domain Vta1 PF04652.16 OWF40634.1 - 0.039 13.9 0.7 1.4 8.9 0.7 2.4 1 1 0 1 1 1 0 Vta1 like C1_1 PF00130.22 OWF40634.1 - 0.15 12.0 12.7 0.088 12.7 10.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OWF40634.1 - 1.2 8.7 8.4 0.36 10.4 1.6 2.9 3 0 0 3 3 3 0 PHD-finger DEAD PF00270.29 OWF40635.1 - 9.6e-43 146.0 0.0 9.6e-43 146.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF40635.1 - 1.4e-28 99.5 0.4 1.4e-26 93.0 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OWF40635.1 - 0.018 15.3 2.2 0.065 13.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain CofC PF01983.16 OWF40636.1 - 0.055 12.6 0.1 0.067 12.4 0.1 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like EF-hand_2 PF09068.11 OWF40640.1 - 1.3e-35 122.2 0.0 4.6e-35 120.4 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 OWF40640.1 - 1.8e-24 85.9 0.0 6.9e-24 84.1 0.0 2.1 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 OWF40640.1 - 8.9e-11 41.4 8.9 1.7e-10 40.5 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF4407 PF14362.6 OWF40640.1 - 0.00049 19.5 7.7 0.021 14.2 0.6 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) AIP3 PF03915.13 OWF40640.1 - 0.0012 18.1 6.8 0.0031 16.7 6.7 1.7 1 1 0 1 1 1 1 Actin interacting protein 3 C1_2 PF03107.16 OWF40640.1 - 0.0026 18.1 7.7 0.0053 17.0 7.7 1.5 1 0 0 1 1 1 1 C1 domain FapA PF03961.13 OWF40640.1 - 0.0028 16.3 4.1 0.0052 15.4 4.1 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 OWF40640.1 - 0.066 13.4 5.5 0.25 11.6 5.5 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EF-hand_6 PF13405.6 OWF40640.1 - 0.074 13.0 1.0 2.8 8.1 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain CRISPR_Cse2 PF09485.10 OWF40640.1 - 0.99 9.9 7.2 0.23 12.0 2.9 2.2 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF3496 PF12001.8 OWF40640.1 - 3.5 8.0 10.8 4.6 7.7 3.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF3496) DUF2852 PF11014.8 OWF40640.1 - 5.6 7.1 5.9 1.3 9.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SOGA PF11365.8 OWF40640.1 - 7.9 7.7 13.1 1 10.5 7.0 2.7 2 0 0 2 2 2 0 Protein SOGA Symplekin_C PF12295.8 OWF40642.1 - 2.3e-69 233.2 3.7 2.3e-69 233.2 3.7 2.5 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 OWF40642.1 - 4.3e-53 180.3 4.4 4.3e-53 180.3 4.4 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.6 OWF40642.1 - 0.0001 22.6 0.0 1.7 9.1 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 OWF40642.1 - 0.0011 19.0 9.8 0.73 9.9 1.4 4.7 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OWF40642.1 - 0.0041 17.2 0.0 4.1 7.9 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat BUD22 PF09073.10 OWF40642.1 - 8.4 5.6 44.6 10 5.3 39.6 2.4 2 0 0 2 2 2 0 BUD22 Pkinase PF00069.25 OWF40643.1 - 7.7e-21 74.6 0.0 1.7e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40643.1 - 3.8e-15 55.9 0.0 6.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF5395 PF17373.2 OWF40643.1 - 0.083 13.5 0.2 0.35 11.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5395) FA_desaturase PF00487.24 OWF40644.1 - 6.2e-24 85.2 9.1 6.2e-24 85.2 9.1 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 OWF40644.1 - 1.7e-21 75.4 0.2 3e-21 74.6 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF2070 PF09843.9 OWF40644.1 - 0.12 10.7 4.6 0.22 9.8 4.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-C2H2 PF00096.26 OWF40645.1 - 3.8e-18 64.8 23.4 2e-05 24.8 0.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF40645.1 - 5e-16 58.3 20.9 5.7e-07 29.7 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF40645.1 - 4.3e-12 45.8 20.7 0.024 15.5 0.2 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger IBR PF01485.21 OWF40645.1 - 0.00049 20.3 0.8 0.00049 20.3 0.8 2.5 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 OWF40645.1 - 0.015 15.6 12.9 0.18 12.1 0.6 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 OWF40645.1 - 0.016 15.4 7.8 2.9 8.0 0.1 3.3 1 1 1 3 3 3 0 Aberrant zinc-finger Raffinose_syn PF05691.12 OWF40645.1 - 0.023 12.5 0.0 0.038 11.8 0.0 1.3 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Transpos_assoc PF13963.6 OWF40645.1 - 0.042 14.2 4.1 1.3 9.4 0.1 2.9 2 1 1 3 3 3 0 Transposase-associated domain zf-TRAF PF02176.18 OWF40645.1 - 0.044 14.5 12.2 5.8 7.7 0.1 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger CCAP PF11105.8 OWF40645.1 - 0.048 13.6 4.2 1.1 9.2 0.8 2.5 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a CHORD PF04968.12 OWF40645.1 - 0.086 13.6 11.1 6.4 7.6 1.8 3.7 1 1 3 4 4 4 0 CHORD zf-met PF12874.7 OWF40645.1 - 0.1 13.0 7.6 1.2 9.6 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OWF40645.1 - 0.14 12.8 3.9 18 6.0 1.3 3.0 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 OWF40645.1 - 0.59 9.9 6.9 3.6 7.4 0.4 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 OWF40645.1 - 0.74 10.2 5.4 62 4.0 5.4 2.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zinc_ribbon_9 PF14369.6 OWF40645.1 - 0.83 10.0 4.1 2.1 8.7 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon zf_UBZ PF18439.1 OWF40645.1 - 0.83 9.3 3.8 3.1 7.5 0.2 3.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-CGNR PF11706.8 OWF40645.1 - 0.96 9.4 7.0 6.1 6.8 0.6 3.1 3 1 0 3 3 3 0 CGNR zinc finger XPA_N PF01286.18 OWF40645.1 - 3 7.9 5.1 3.1 7.9 0.1 2.9 4 0 0 4 4 4 0 XPA protein N-terminal Globin PF00042.22 OWF40646.1 - 2.8e-15 56.8 0.0 4.8e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Globin MCCD1 PF15707.5 OWF40646.1 - 0.038 14.4 0.1 0.067 13.7 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 DnaB_C PF03796.15 OWF40646.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain Cue1_U7BR PF18499.1 OWF40646.1 - 0.071 13.2 1.2 0.35 11.0 0.3 2.2 1 1 1 2 2 2 0 Ubc7p-binding region of Cue1 Lig_chan PF00060.26 OWF40647.1 - 1e-29 103.3 0.3 1.5e-29 102.8 0.3 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF40647.1 - 6.6e-29 100.4 0.0 1.1e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF40647.1 - 1.2e-25 90.3 0.0 1.7e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 OWF40647.1 - 0.019 14.9 5.1 0.059 13.3 3.8 2.3 2 0 0 2 2 2 0 Ion channel GSDH PF07995.11 OWF40648.1 - 9.2e-46 156.7 0.1 1.4e-45 156.1 0.1 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SNARE PF05739.19 OWF40649.1 - 1.3e-16 60.3 1.7 1.7e-16 60.0 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 OWF40649.1 - 4.3e-06 25.8 0.2 1.4e-05 24.2 0.2 2.0 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 OWF40649.1 - 0.0098 15.6 2.6 0.0098 15.6 2.6 3.1 2 1 1 3 3 3 2 Syntaxin DUF16 PF01519.16 OWF40649.1 - 0.033 14.7 3.2 0.033 14.7 3.2 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 Apolipoprotein PF01442.18 OWF40649.1 - 0.078 12.8 6.6 0.077 12.9 0.7 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain AI-2E_transport PF01594.16 OWF40649.1 - 1.5 7.9 7.2 0.058 12.6 1.0 1.7 2 0 0 2 2 2 0 AI-2E family transporter SKA1 PF07160.12 OWF40649.1 - 2.5 7.9 16.5 0.19 11.5 2.6 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 OWF40649.1 - 4.3 7.7 8.2 6.7 7.1 0.5 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OWF40649.1 - 5.8 7.0 15.8 2.5 8.1 4.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 OWF40649.1 - 5.9 7.2 7.0 2.1 8.6 0.0 3.4 4 0 0 4 4 4 0 Haemolysin XhlA Met_synt_B12 PF02965.17 OWF40650.1 - 1.7e-112 375.4 0.0 2.8e-112 374.7 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 OWF40650.1 - 3.3e-76 256.7 0.0 6e-76 255.8 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 OWF40650.1 - 2.7e-57 194.3 0.4 1e-56 192.3 0.3 2.1 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 OWF40650.1 - 8.3e-23 80.6 0.0 2.5e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 OWF40650.1 - 6.4e-19 68.2 0.8 6.6e-18 64.9 0.3 2.8 3 0 0 3 3 3 1 B12 binding domain CdhD PF03599.16 OWF40650.1 - 0.011 14.5 0.1 0.021 13.5 0.1 1.4 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit 2OG-FeII_Oxy_3 PF13640.6 OWF40651.1 - 4.4e-11 43.5 0.1 7.9e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 OWF40651.1 - 0.031 13.4 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus C4/C10 protein 2OG-FeII_Oxy_5 PF13759.6 OWF40651.1 - 0.037 14.4 0.3 0.087 13.2 0.0 1.7 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Pkinase_Tyr PF07714.17 OWF40652.1 - 2.3e-88 295.9 0.0 3.6e-88 295.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF40652.1 - 1.1e-42 146.3 0.0 1.6e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF40652.1 - 4e-14 52.5 0.1 9.9e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 OWF40652.1 - 1.4e-10 40.6 0.0 2.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF40652.1 - 6e-08 32.4 0.0 1.7e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF40652.1 - 2.4e-05 23.9 0.0 5.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 OWF40652.1 - 0.0034 17.3 0.0 0.045 13.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family ERO1 PF04137.15 OWF40653.1 - 6.3e-110 367.7 0.5 7.7e-110 367.4 0.5 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) EcsC PF12787.7 OWF40653.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 EcsC protein family Methyltransf_28 PF02636.17 OWF40654.1 - 1.5e-73 247.7 0.0 1.9e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhamno_transf PF11316.8 OWF40654.1 - 0.17 11.2 0.0 0.57 9.5 0.0 1.8 2 0 0 2 2 2 0 Putative rhamnosyl transferase B9-C2 PF07162.11 OWF40655.1 - 6.2e-59 199.0 0.0 7e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein C2 PF00168.30 OWF40655.1 - 0.039 14.2 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 C2 domain SQHop_cyclase_C PF13243.6 OWF40655.1 - 0.047 12.8 0.1 0.062 12.4 0.1 1.1 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Tyr-DNA_phospho PF06087.12 OWF40656.1 - 3.3e-124 415.0 0.0 5.5e-124 414.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 OWF40656.1 - 1.5e-11 44.1 4.4 3.4e-11 42.9 4.4 1.6 1 0 0 1 1 1 1 PBZ domain TPR_2 PF07719.17 OWF40657.1 - 1.6e-19 68.4 6.4 0.071 13.2 0.1 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF40657.1 - 1.6e-17 62.5 4.9 0.22 11.4 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF40657.1 - 1.7e-16 59.5 1.7 0.22 12.4 0.2 6.9 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OWF40657.1 - 1.3e-13 50.0 9.7 0.078 13.2 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF40657.1 - 2.4e-12 47.3 0.0 0.083 13.6 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OWF40657.1 - 3e-08 33.5 5.4 0.54 10.8 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF40657.1 - 1.3e-07 32.0 7.6 0.037 14.5 0.0 5.2 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF40657.1 - 1.8e-07 31.3 9.6 0.31 11.3 0.0 6.1 2 2 5 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF40657.1 - 3.2e-06 27.3 11.2 0.029 14.6 1.1 4.3 3 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 OWF40657.1 - 3.4e-05 23.4 1.3 0.61 9.5 0.1 3.3 2 1 1 3 3 3 2 Coatomer epsilon subunit TPR_11 PF13414.6 OWF40657.1 - 7.5e-05 22.3 4.9 0.00059 19.5 0.0 4.2 5 1 1 6 6 6 1 TPR repeat TPR_7 PF13176.6 OWF40657.1 - 7.7e-05 22.5 5.5 5.9 7.2 0.0 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 OWF40657.1 - 0.00021 20.6 1.7 0.00071 18.9 0.4 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF40657.1 - 0.00037 20.6 0.0 0.73 10.0 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 OWF40657.1 - 0.0047 16.7 0.4 0.11 12.2 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain FAT PF02259.23 OWF40657.1 - 0.0062 15.8 1.0 0.57 9.3 0.0 3.0 2 2 0 2 2 2 1 FAT domain BTAD PF03704.17 OWF40657.1 - 0.1 13.1 1.4 1.2 9.6 0.5 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_MalT PF17874.1 OWF40657.1 - 0.11 11.8 0.1 0.62 9.4 0.0 2.2 2 1 0 2 2 2 0 MalT-like TPR region Tyr_Deacylase PF02580.16 OWF40658.1 - 6.2e-53 179.2 0.0 7.8e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase zf-C3HC4_3 PF13920.6 OWF40659.1 - 2.2e-10 40.2 11.3 2.2e-10 40.2 11.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Endonuclease_7 PF02945.15 OWF40659.1 - 5 7.1 11.2 1.2 9.1 0.3 2.8 2 1 0 2 2 2 0 Recombination endonuclease VII CLASP_N PF12348.8 OWF40660.1 - 1.4e-19 70.6 9.0 3.8e-10 39.7 0.0 4.2 5 0 0 5 5 5 2 CLASP N terminal HEAT PF02985.22 OWF40660.1 - 7.1e-11 41.4 3.9 0.17 12.2 0.3 9.0 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 OWF40660.1 - 1.7e-07 31.5 0.6 1 9.8 0.0 5.0 4 1 1 5 5 5 3 HEAT repeats RTP1_C1 PF10363.9 OWF40660.1 - 1.9e-07 31.2 7.8 0.19 11.9 0.2 6.1 4 2 0 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OWF40660.1 - 9.6e-06 25.7 14.7 0.22 11.5 1.7 6.2 4 3 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OWF40660.1 - 1.6e-05 23.7 15.9 0.02 13.5 1.0 5.0 4 1 0 5 5 5 2 Adaptin N terminal region Dopey_N PF04118.14 OWF40660.1 - 1.6e-05 24.2 1.4 0.46 9.6 0.1 3.7 3 0 0 3 3 3 2 Dopey, N-terminal Cohesin_HEAT PF12765.7 OWF40660.1 - 0.0006 20.1 1.7 1.5 9.2 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 OWF40660.1 - 0.0022 18.6 3.5 41 4.9 0.0 5.2 5 1 0 5 5 4 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 OWF40660.1 - 0.0022 17.8 2.9 4.4 7.0 0.0 4.4 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis Tti2 PF10521.9 OWF40660.1 - 0.041 13.4 0.0 0.041 13.4 0.0 3.1 4 0 0 4 4 4 0 Tti2 family NUC173 PF08161.12 OWF40660.1 - 0.14 11.8 2.9 0.65 9.6 0.3 3.4 3 1 1 4 4 4 0 NUC173 domain HEAT_EZ PF13513.6 OWF40660.1 - 0.14 12.7 2.1 23 5.6 0.1 4.9 5 1 0 5 5 4 0 HEAT-like repeat Rap1_C PF11626.8 OWF40660.1 - 0.94 9.6 3.4 3.2 7.9 0.0 3.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Lectin_C PF00059.21 OWF40661.1 - 2.5e-17 63.6 0.4 3.7e-17 63.0 0.4 1.3 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 OWF40662.1 - 3.1e-20 72.9 0.7 4e-20 72.6 0.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 OWF40663.1 - 1.3e-20 74.1 0.5 1.8e-20 73.7 0.5 1.2 1 0 0 1 1 1 1 Lectin C-type domain 7tm_1 PF00001.21 OWF40664.1 - 2.9e-19 69.4 10.2 2.9e-19 69.4 10.2 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF40664.1 - 3.9e-16 59.2 16.9 1.1e-15 57.7 16.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF40664.1 - 2.5e-06 27.1 14.4 1.6e-05 24.5 14.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF40664.1 - 7.6e-05 22.5 12.0 7.6e-05 22.5 12.0 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CbtB PF09489.10 OWF40664.1 - 0.13 12.3 0.1 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Srg PF02118.21 OWF40664.1 - 0.38 10.4 23.7 0.013 15.2 11.2 2.7 2 1 0 2 2 2 0 Srg family chemoreceptor DUF4281 PF14108.6 OWF40664.1 - 0.69 10.3 6.6 0.92 9.9 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) Lipase_GDSL PF00657.22 OWF40665.1 - 0.00063 19.8 0.0 0.00067 19.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF40665.1 - 0.0013 19.1 0.0 0.0015 19.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 OWF40666.1 - 8.1e-16 57.9 46.3 8.1e-16 57.9 46.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily IgGFc_binding PF17517.2 OWF40667.1 - 3.8e-38 131.4 0.0 3.8e-38 131.4 0.0 2.0 2 0 0 2 2 2 1 IgGFc binding protein Fringe PF02434.16 OWF40668.1 - 3.7e-13 49.5 0.5 1.8e-12 47.2 0.5 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF40668.1 - 6.6e-09 35.9 0.1 0.00011 22.1 0.4 2.3 1 1 1 2 2 2 2 Galactosyltransferase LAP2alpha PF11560.8 OWF40669.1 - 0.0049 16.3 0.3 0.029 13.8 0.2 2.0 1 1 0 1 1 1 1 Lamina-associated polypeptide 2 alpha CfAFP PF05264.11 OWF40669.1 - 0.047 13.7 14.3 0.057 13.4 14.3 1.2 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF4517 PF15006.6 OWF40669.1 - 0.1 12.7 2.8 0.12 12.5 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) UBA2_C PF16195.5 OWF40669.1 - 6.3 7.6 8.2 1.6 9.5 1.6 2.2 1 1 1 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Fringe PF02434.16 OWF40670.1 - 5.5e-13 48.9 0.6 2.6e-12 46.7 0.6 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF40670.1 - 1.3e-08 34.9 0.1 7.3e-05 22.7 0.3 2.3 1 1 1 2 2 2 2 Galactosyltransferase CARD_2 PF16739.5 OWF40671.1 - 9.4e-16 57.6 0.0 3.9e-14 52.4 0.0 2.7 2 0 0 2 2 2 1 Caspase recruitment domain Death PF00531.22 OWF40671.1 - 0.00026 21.1 0.0 0.00069 19.7 0.0 1.7 1 0 0 1 1 1 1 Death domain Lipoprotein_1 PF00820.19 OWF40671.1 - 0.023 13.8 0.1 0.061 12.4 0.1 1.7 1 0 0 1 1 1 0 Borrelia lipoprotein Com_YlbF PF06133.11 OWF40671.1 - 0.038 14.6 1.9 12 6.6 0.1 3.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Phage_pRha PF09669.10 OWF40671.1 - 0.076 13.6 0.1 0.29 11.7 0.1 2.0 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) COMM_domain PF07258.14 OWF40672.1 - 1.1e-17 63.9 0.0 1.6e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 COMM domain Lip_prot_lig_C PF10437.9 OWF40672.1 - 0.097 12.7 0.1 5.3 7.1 0.0 2.7 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus SasG_E PF17041.5 OWF40672.1 - 0.1 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 E domain NPV_P10 PF05531.12 OWF40673.1 - 0.16 12.4 3.8 3 8.4 0.6 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.24 OWF40673.1 - 0.17 11.8 13.4 0.48 10.3 7.2 2.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 OWF40673.1 - 1.1 9.3 10.4 0.69 10.0 1.4 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF2730 PF10805.8 OWF40673.1 - 2.7 8.1 9.6 2.8 8.1 4.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) USP8_interact PF08941.10 OWF40673.1 - 6.1 6.6 8.5 8.8 6.1 2.6 3.1 3 0 0 3 3 3 0 USP8 interacting Aldo_ket_red PF00248.21 OWF40674.1 - 1.8e-54 184.9 0.0 2.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 OWF40675.1 - 1.1e-52 179.1 0.0 1.3e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1572 PF07609.11 OWF40676.1 - 0.0016 18.3 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1572) DED PF01335.21 OWF40676.1 - 0.0036 17.6 0.0 0.53 10.6 0.0 2.5 2 1 0 2 2 2 2 Death effector domain PfUIS3 PF11567.8 OWF40676.1 - 0.0097 16.2 1.7 1.2 9.5 0.0 3.2 2 1 1 3 3 3 1 Plasmodium falciparum UIS3 membrane protein AAA_32 PF13654.6 OWF40676.1 - 0.017 14.0 0.3 0.093 11.5 0.2 1.8 2 0 0 2 2 2 0 AAA domain DED PF01335.21 OWF40677.1 - 5.6e-09 36.2 0.0 0.00096 19.4 0.0 2.3 2 0 0 2 2 2 2 Death effector domain SPATA48 PF15073.6 OWF40678.1 - 2.6e-42 144.1 0.8 4.8e-42 143.3 0.8 1.4 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 An_peroxidase PF03098.15 OWF40679.1 - 0 1101.4 0.0 2.8e-171 570.7 0.0 2.1 2 0 0 2 2 2 2 Animal haem peroxidase HAUS6_N PF14661.6 OWF40679.1 - 0.0063 16.1 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 6 N-terminus Striatin PF08232.12 OWF40679.1 - 0.018 15.7 4.0 6.4 7.4 3.2 3.2 3 0 0 3 3 3 0 Striatin family DUF4035 PF13227.6 OWF40679.1 - 0.029 14.1 1.0 23 4.8 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4035) Cas9_b_hairpin PF17893.1 OWF40679.1 - 0.031 14.1 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain Hemocyanin_N PF03722.14 OWF40679.1 - 0.11 13.0 0.0 33 5.0 0.0 2.9 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain Ank_2 PF12796.7 OWF40680.1 - 3.2e-24 85.3 0.1 1.3e-13 51.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF40680.1 - 3.9e-16 59.2 0.4 1.4e-06 28.7 0.0 3.6 3 1 1 4 4 3 2 Ankyrin repeats (many copies) zf-RING_6 PF14835.6 OWF40680.1 - 7.9e-15 54.5 7.4 2e-14 53.2 7.4 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Ank_5 PF13857.6 OWF40680.1 - 2e-14 53.5 1.2 9.6e-08 32.2 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF40680.1 - 2e-12 46.9 1.7 8.4e-05 22.8 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OWF40680.1 - 6.3e-12 44.6 0.1 2.8e-05 24.1 0.1 4.1 4 0 0 4 4 3 2 Ankyrin repeat BRCT PF00533.26 OWF40680.1 - 3.3e-07 30.6 0.0 9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.6 OWF40680.1 - 0.00048 19.9 13.2 0.0015 18.4 13.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT_2 PF16589.5 OWF40680.1 - 0.00057 20.2 0.0 0.0017 18.8 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OWF40680.1 - 0.0025 17.7 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Prok-RING_4 PF14447.6 OWF40680.1 - 0.0059 16.4 14.0 0.018 14.9 14.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF40680.1 - 0.0071 16.7 14.6 0.025 14.9 14.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OWF40680.1 - 0.015 15.2 12.7 0.047 13.6 12.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF40680.1 - 0.019 14.9 14.3 0.019 14.9 14.3 2.1 2 0 0 2 2 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF40680.1 - 0.16 12.1 10.1 0.76 9.9 10.1 2.3 1 1 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.11 OWF40680.1 - 0.34 11.0 9.1 1.2 9.3 9.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) HECT PF00632.25 OWF40681.1 - 4.1e-97 325.4 0.0 6.3e-97 324.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 OWF40681.1 - 5.6e-36 123.0 0.1 1.1e-35 122.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 OWF40681.1 - 6.7e-27 93.4 3.6 2.9e-25 88.2 1.8 2.6 2 0 0 2 2 2 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 OWF40681.1 - 1.3e-17 63.6 0.4 7.4e-11 41.9 0.1 3.1 3 0 0 3 3 3 2 WW domain C2 PF00168.30 OWF40681.1 - 2.7e-09 37.3 0.0 5.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain IDEAL PF08858.10 OWF40682.1 - 2.1e-05 24.2 0.1 8.3 6.2 0.0 5.8 5 2 1 6 6 6 1 IDEAL domain GATase PF00117.28 OWF40682.1 - 0.011 15.5 6.2 8.4 6.1 0.4 4.0 1 1 3 4 4 4 0 Glutamine amidotransferase class-I DUF938 PF06080.12 OWF40682.1 - 0.026 14.3 11.8 0.52 10.0 0.5 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF938) YmzC PF14157.6 OWF40682.1 - 0.044 13.9 19.2 1.8 8.7 0.2 5.6 2 1 3 5 5 5 0 YmzC-like protein DUF3640 PF12342.8 OWF40682.1 - 0.075 12.8 0.0 1.4e+02 2.3 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3640) Sars6 PF12133.8 OWF40682.1 - 0.14 12.1 1.1 69 3.5 0.0 4.0 3 2 0 4 4 4 0 Open reading frame 6 from SARS coronavirus CdiI_2 PF18593.1 OWF40682.1 - 0.99 10.1 9.8 60 4.4 0.1 4.8 1 1 4 5 5 5 0 CdiI immunity protein Rap1_C PF11626.8 OWF40682.1 - 1.2 9.2 4.6 1.3e+02 2.8 4.6 4.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF938 PF06080.12 OWF40683.1 - 0.0067 16.2 3.1 1.1 9.0 0.2 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF938) GATase PF00117.28 OWF40683.1 - 0.036 13.8 1.2 4.6 7.0 0.1 2.5 1 1 1 2 2 2 0 Glutamine amidotransferase class-I Hydrolase_3 PF08282.12 OWF40683.1 - 0.047 13.4 3.3 9.3 5.9 0.2 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PHD20L1_u1 PF16660.5 OWF40683.1 - 0.056 14.2 3.1 3.3 8.5 0.2 3.0 1 1 2 3 3 3 0 PHD finger protein 20-like protein 1 Transposase_23 PF03017.14 OWF40683.1 - 0.096 12.6 0.0 70 3.5 0.0 4.2 1 1 5 6 6 6 0 TNP1/EN/SPM transposase CdiI_2 PF18593.1 OWF40683.1 - 0.29 11.8 3.3 18 6.0 0.1 3.3 1 1 3 4 4 4 0 CdiI immunity protein YmzC PF14157.6 OWF40683.1 - 0.33 11.1 9.6 12 6.1 0.2 4.2 1 1 4 5 5 5 0 YmzC-like protein WD40 PF00400.32 OWF40684.1 - 8.2e-20 70.8 12.2 0.00016 22.4 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OWF40684.1 - 0.00066 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF40684.1 - 0.12 12.2 0.2 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OWF40685.1 - 1.9e-15 57.0 2.3 0.00024 21.9 0.0 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat Amidase PF01425.21 OWF40686.1 - 2.8e-99 333.1 0.0 3.1e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF2733 PF10813.8 OWF40687.1 - 1.3e-05 24.9 2.3 5.7 6.8 0.1 5.0 5 0 0 5 5 5 2 Protein of unknown function (DUF2733) zf-C2H2 PF00096.26 OWF40687.1 - 0.0039 17.6 9.0 16 6.2 0.1 5.4 5 1 0 5 5 5 1 Zinc finger, C2H2 type HSV_VP16_C PF12149.8 OWF40687.1 - 0.053 13.6 0.9 1.2e+02 2.9 0.0 4.1 4 1 1 5 5 5 0 Herpes simplex virus virion protein 16 C terminal WD40 PF00400.32 OWF40688.1 - 3.4e-35 119.5 25.0 2.3e-05 25.1 0.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.12 OWF40688.1 - 3.3e-20 72.4 0.1 5.2e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 OWF40688.1 - 0.026 13.2 8.3 0.038 12.7 0.7 3.2 1 1 2 4 4 4 0 Nucleoporin Nup120/160 NCBP3 PF10309.9 OWF40688.1 - 0.15 12.0 0.6 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 CpcD PF01383.21 OWF40688.1 - 0.22 11.8 0.0 0.46 10.8 0.0 1.5 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain PEHE PF15275.6 OWF40689.1 - 1.2e-21 77.7 1.7 1.2e-21 77.7 1.7 3.5 1 1 1 3 3 3 1 PEHE domain MSL1_dimer PF16801.5 OWF40689.1 - 0.27 11.0 7.6 0.92 9.3 7.6 1.9 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Cpn10 PF00166.21 OWF40690.1 - 2.9e-25 88.1 0.1 3.4e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 OWF40691.1 - 1.2e-83 281.4 13.6 5.3e-83 279.3 13.6 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aminotran_1_2 PF00155.21 OWF40691.1 - 0.14 11.3 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II 4HB_MCP_1 PF12729.7 OWF40691.1 - 0.42 10.1 2.2 5.4 6.5 0.3 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Tom7 PF08038.12 OWF40692.1 - 7.4e-13 47.9 0.0 1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 TOM7 family PPP5 PF08321.12 OWF40692.1 - 0.079 13.3 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 PPP5 TPR repeat region MRJP PF03022.16 OWF40693.1 - 3.7e-41 141.4 3.5 6.4e-41 140.6 3.5 1.2 1 0 0 1 1 1 1 Major royal jelly protein DUF4996 PF16387.5 OWF40693.1 - 0.083 13.4 0.1 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function Ank_2 PF12796.7 OWF40694.1 - 2.7e-132 431.6 79.1 6.1e-16 58.8 1.8 9.7 1 1 12 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF40694.1 - 1.4e-81 267.9 42.6 6.6e-12 45.7 0.1 13.7 6 3 8 15 15 15 15 Ankyrin repeats (many copies) Ank PF00023.30 OWF40694.1 - 6.8e-70 228.7 63.3 9.4e-06 25.8 0.2 18.1 18 0 0 18 18 18 16 Ankyrin repeat Ank_3 PF13606.6 OWF40694.1 - 4.3e-69 220.2 46.1 4.8e-05 23.4 0.1 18.2 18 0 0 18 18 18 16 Ankyrin repeat Ank_5 PF13857.6 OWF40694.1 - 5.3e-65 214.6 46.5 4.3e-08 33.3 0.2 14.2 5 3 9 15 15 15 15 Ankyrin repeats (many copies) DUF2520 PF10728.9 OWF40694.1 - 0.0063 16.3 8.0 0.032 14.0 1.3 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF2520) Prok-RING_1 PF14446.6 OWF40694.1 - 0.41 10.6 6.0 2.5 8.1 0.1 4.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 Ank_4 PF13637.6 OWF40695.1 - 2e-47 159.0 7.4 6.5e-13 48.9 0.1 4.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF40695.1 - 5.4e-47 158.3 9.8 2.2e-18 66.6 1.6 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF40695.1 - 1.3e-33 113.9 3.0 4.3e-06 26.9 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OWF40695.1 - 8.6e-32 105.6 1.4 3.5e-06 26.9 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 OWF40695.1 - 5.5e-31 106.2 4.2 1.6e-07 31.5 0.5 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) DUF2520 PF10728.9 OWF40695.1 - 0.078 12.8 1.8 2.6 7.8 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF2520) Colipase-like PF15083.6 OWF40696.1 - 8e-13 48.3 26.4 0.0061 16.7 1.0 5.2 1 1 2 4 4 4 4 Colipase-like zf-TAZ PF02135.16 OWF40697.1 - 0.00096 19.6 20.2 0.0074 16.7 5.7 3.7 1 1 2 3 3 3 3 TAZ zinc finger Cys_Knot_tox PF17486.2 OWF40697.1 - 6.3 7.1 32.6 5.7 7.2 2.7 4.9 1 1 5 6 6 6 0 Cystine knot toxins zinc-ribbons_6 PF07191.12 OWF40697.1 - 7.7 6.6 12.9 9.4 6.3 1.6 3.2 1 1 2 3 3 3 0 zinc-ribbons 7tm_1 PF00001.21 OWF40698.1 - 4.4e-70 236.0 9.8 7e-70 235.4 9.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF40698.1 - 5.9e-08 32.4 16.2 5.5e-06 25.9 13.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Spore_III_AB PF09548.10 OWF40698.1 - 0.03 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Phage_holin_3_6 PF07332.11 OWF40698.1 - 0.27 11.3 0.0 0.27 11.3 0.0 3.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MM_CoA_mutase PF01642.22 OWF40699.1 - 9.4e-237 786.6 0.2 1.1e-236 786.4 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 OWF40699.1 - 7.6e-15 55.0 0.1 1.8e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 B12 binding domain PV-1 PF06637.11 OWF40699.1 - 0.17 10.7 3.1 0.2 10.4 0.8 1.9 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Carb_anhydrase PF00194.21 OWF40700.1 - 1.6e-61 208.1 0.0 2.3e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase 7tm_2 PF00002.24 OWF40701.1 - 1.3e-58 198.2 16.1 1.9e-58 197.6 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF40701.1 - 1.4e-15 57.3 6.5 1.4e-15 57.3 6.5 2.3 2 0 0 2 2 2 1 Hormone receptor domain Dicty_CAR PF05462.11 OWF40701.1 - 0.085 12.0 15.8 0.13 11.3 15.8 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Baculo_11_kDa PF06143.11 OWF40701.1 - 0.64 9.6 4.3 0.42 10.2 0.6 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family MFS_1 PF07690.16 OWF40703.1 - 1.8e-06 27.1 29.7 1.1e-05 24.6 29.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily HC2 PF07382.11 OWF40704.1 - 0.00016 21.8 52.4 0.074 13.1 22.6 3.0 1 1 2 3 3 3 3 Histone H1-like nucleoprotein HC2 Sugar_tr PF00083.24 OWF40707.1 - 7.8e-06 25.0 1.5 8.3e-06 24.9 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF40707.1 - 0.00025 20.1 10.8 0.00033 19.7 10.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF40708.1 - 1.6e-13 50.3 93.7 9.9e-07 28.0 27.2 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DAGAT PF03982.13 OWF40709.1 - 4.4e-114 380.4 0.1 5.6e-114 380.0 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DP PF08781.10 OWF40711.1 - 4.4e-61 204.8 1.6 9.3e-61 203.7 1.6 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 OWF40711.1 - 2.9e-26 91.3 0.0 6.1e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Pkinase_Tyr PF07714.17 OWF40712.1 - 4.6e-86 288.3 0.0 6.6e-86 287.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF40712.1 - 1.4e-44 152.5 0.0 2.8e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 OWF40712.1 - 1.2e-36 125.1 1.1 2e-13 50.7 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) SH2 PF00017.24 OWF40712.1 - 2.6e-32 110.7 0.3 1.9e-19 69.5 0.0 2.5 2 0 0 2 2 2 2 SH2 domain Ank_4 PF13637.6 OWF40712.1 - 1.7e-21 76.3 2.0 8.2e-09 35.8 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF40712.1 - 6e-21 74.2 0.4 1.4e-11 44.4 0.0 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF40712.1 - 5.7e-18 64.5 0.9 0.00073 19.9 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 OWF40712.1 - 9.6e-13 47.1 1.4 0.29 11.8 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Kinase-like PF14531.6 OWF40712.1 - 1.1e-05 25.0 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF40712.1 - 0.00054 19.0 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF40712.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family THAP PF05485.12 OWF40713.1 - 7e-11 42.9 2.6 9.9e-11 42.4 2.6 1.3 1 1 0 1 1 1 1 THAP domain Myb_DNA-bind_4 PF13837.6 OWF40714.1 - 8.7e-10 38.9 1.7 1.3e-09 38.3 1.1 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain F-box-like PF12937.7 OWF40714.1 - 8.6e-09 35.2 0.1 3.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OWF40714.1 - 7.6e-07 28.9 0.0 2.6e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain MADF_DNA_bdg PF10545.9 OWF40714.1 - 8.7e-06 26.0 0.5 1.9e-05 24.9 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 OWF40714.1 - 0.0046 17.0 0.5 0.011 15.8 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain F-box_4 PF15966.5 OWF40714.1 - 0.048 13.6 0.6 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 F-box PRANC PF09372.10 OWF40714.1 - 0.072 13.4 0.1 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 PRANC domain Pkinase PF00069.25 OWF40715.1 - 3e-137 456.3 0.0 6.9e-68 228.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40715.1 - 5e-63 212.8 0.0 5e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OWF40715.1 - 2.3e-13 50.1 0.0 5.4e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OWF40715.1 - 2.6e-10 40.0 0.7 2.5e-06 27.0 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF40715.1 - 1.6e-08 34.8 0.3 0.0067 16.4 0.0 3.6 2 2 1 3 3 3 3 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF40715.1 - 2.7e-08 33.2 4.3 0.0002 20.5 0.2 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 OWF40715.1 - 1.1e-07 31.0 0.7 3.1e-05 22.9 0.0 3.2 5 0 0 5 5 5 2 Fungal protein kinase FTA2 PF13095.6 OWF40715.1 - 6e-06 26.0 0.7 0.76 9.4 0.0 3.4 3 0 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 OWF40715.1 - 3.7e-05 24.3 0.1 0.00018 22.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Choline_kinase PF01633.20 OWF40715.1 - 0.12 12.0 0.1 0.82 9.2 0.0 2.2 2 1 0 2 2 2 0 Choline/ethanolamine kinase HEAT PF02985.22 OWF40717.1 - 1.5e-10 40.4 6.9 0.18 12.1 0.0 8.0 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 OWF40717.1 - 8.5e-05 22.9 0.1 0.3 11.5 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 OWF40717.1 - 0.056 13.5 4.1 0.1 12.7 0.1 3.4 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Calx-beta PF03160.14 OWF40718.1 - 1.8e-17 63.3 0.0 5.6e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 Calx-beta domain cEGF PF12662.7 OWF40718.1 - 0.00016 21.5 11.1 0.035 14.0 2.8 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 OWF40718.1 - 0.0069 16.7 8.8 0.0069 16.7 8.8 3.5 3 0 0 3 3 3 1 Pvs28 EGF domain hEGF PF12661.7 OWF40718.1 - 0.063 13.9 2.6 0.063 13.9 2.6 5.1 5 1 0 5 5 5 0 Human growth factor-like EGF Laminin_EGF PF00053.24 OWF40718.1 - 0.3 11.3 31.5 0.26 11.5 5.1 3.6 2 2 1 3 3 3 0 Laminin EGF domain Patched PF02460.18 OWF40719.1 - 2.6e-09 35.8 0.3 3.2e-09 35.5 0.3 1.0 1 0 0 1 1 1 1 Patched family VirDNA-topo-I_N PF09266.10 OWF40719.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal ketoacyl-synt PF00109.26 OWF40720.1 - 8.4e-16 58.3 0.0 8.8e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain GHL10 PF02638.15 OWF40721.1 - 2.9e-74 250.0 0.6 4e-74 249.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_hydro_66 PF13199.6 OWF40721.1 - 0.0013 17.5 0.4 0.0034 16.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 66 Sulfotransfer_2 PF03567.14 OWF40722.1 - 3.9e-27 95.8 0.4 3e-24 86.3 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family HEPN_DZIP3 PF18738.1 OWF40723.1 - 5.6e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN TIR_2 PF13676.6 OWF40723.1 - 0.088 13.4 0.0 0.21 12.2 0.0 1.6 1 1 0 1 1 1 0 TIR domain PHD PF00628.29 OWF40724.1 - 1.4e-10 40.9 9.1 2.8e-10 39.9 9.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 OWF40724.1 - 2.1e-05 24.2 3.7 2.1e-05 24.2 3.7 2.9 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 OWF40724.1 - 0.00014 21.7 2.0 0.00014 21.7 2.0 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OWF40724.1 - 0.0077 15.8 4.7 0.0077 15.8 4.7 1.7 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 OWF40724.1 - 0.044 13.9 9.4 0.22 11.7 9.4 2.4 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 OWF40724.1 - 0.19 11.7 8.3 0.039 13.9 4.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_15 PF17032.5 OWF40724.1 - 3.4 8.5 8.8 1.2 10.0 4.9 2.3 1 1 1 2 2 2 0 zinc-ribbon family Zf_RING PF16744.5 OWF40724.1 - 3.5 7.8 7.8 16 5.7 7.9 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 OWF40724.1 - 8.4 6.8 8.1 18 5.7 8.1 1.6 1 1 0 1 1 1 0 Ring finger domain FAD_binding_7 PF03441.14 OWF40725.1 - 1.5e-77 259.6 0.3 2.3e-77 259.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OWF40725.1 - 3.1e-42 144.3 0.0 6.1e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Gag_p10 PF02337.17 OWF40725.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral GAG p10 protein Ldl_recept_b PF00058.17 OWF40727.1 - 1e-166 541.2 56.7 9.4e-13 48.4 0.1 20.9 21 0 0 21 21 21 20 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 OWF40727.1 - 6.6e-85 279.0 189.3 4.4e-12 46.0 11.8 10.1 9 0 0 9 9 9 9 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 OWF40727.1 - 2.6e-48 162.0 151.8 3.2e-12 46.5 9.6 10.4 11 0 0 11 11 7 6 Coagulation Factor Xa inhibitory site SGL PF08450.12 OWF40727.1 - 6.1e-19 68.6 25.0 0.0044 16.6 1.0 11.1 3 3 5 8 8 8 6 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 OWF40727.1 - 2.2e-13 49.9 44.6 4.3e-05 23.3 0.5 8.1 7 0 0 7 7 7 5 Complement Clr-like EGF-like DUF5050 PF16472.5 OWF40727.1 - 3.2e-12 46.3 0.0 0.067 12.4 0.0 6.2 5 3 2 7 7 7 4 Domain of unknown function (DUF5050) NHL PF01436.21 OWF40727.1 - 1.6e-06 27.8 0.6 53 4.1 0.0 8.6 9 0 0 9 9 9 0 NHL repeat EGF_CA PF07645.15 OWF40727.1 - 8.5e-06 25.9 7.9 8.5e-06 25.9 7.9 14.8 7 2 6 14 14 8 1 Calcium-binding EGF domain SBBP PF06739.11 OWF40727.1 - 0.0016 18.4 0.0 2 8.5 0.0 4.4 5 0 0 5 5 5 1 Beta-propeller repeat EGF PF00008.27 OWF40727.1 - 0.0054 17.0 6.4 0.0054 17.0 6.4 12.4 14 1 1 15 15 11 6 EGF-like domain DUF2627 PF11118.8 OWF40727.1 - 0.19 12.3 0.0 0.5 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Mab-21 PF03281.14 OWF40728.1 - 2e-30 106.1 0.1 2.7e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Mab-21 protein NTP_transf_2 PF01909.23 OWF40728.1 - 0.068 13.5 0.0 0.39 11.0 0.0 2.3 3 0 0 3 3 3 0 Nucleotidyltransferase domain Dimerisation PF08100.11 OWF40729.1 - 5.5e-15 55.1 2.9 0.16 12.0 0.1 6.2 3 3 4 7 7 7 7 Dimerisation domain DbpA PF03880.15 OWF40729.1 - 1.5e-07 31.3 0.2 39 4.3 0.0 6.8 1 1 8 9 9 9 4 DbpA RNA binding domain adh_short PF00106.25 OWF40730.1 - 1.5e-45 155.1 0.0 2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF40730.1 - 8.4e-25 87.7 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF40730.1 - 2e-12 47.4 0.0 3.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OWF40730.1 - 0.00044 19.5 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OWF40730.1 - 0.0024 17.3 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 OWF40730.1 - 0.0026 17.2 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.10 OWF40730.1 - 0.003 17.0 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 OWF40730.1 - 0.0046 16.9 0.1 0.0073 16.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OWF40730.1 - 0.006 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OWF40730.1 - 0.02 15.0 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OWF40730.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OWF40730.1 - 0.021 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 OWF40730.1 - 0.054 12.8 0.1 0.57 9.4 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.19 OWF40730.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 OWF40730.1 - 0.064 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C3HC4_5 PF17121.5 OWF40731.1 - 2.2e-15 56.2 99.3 6.6 6.7 0.2 19.7 1 1 19 20 20 20 17 Zinc finger, C3HC4 type (RING finger) Spidroin_N PF16763.5 OWF40731.1 - 2.8e-08 33.8 10.4 59 3.7 0.1 9.0 1 1 15 16 16 16 0 Major ampullate spidroin 1, spider silk protein 1, N-term MatK_N PF01824.18 OWF40731.1 - 2.2e-06 27.6 10.5 62 3.1 0.0 7.9 1 1 16 17 17 17 0 MatK/TrnK amino terminal region DNA_pol_phi PF04931.13 OWF40731.1 - 1.3e-05 23.5 14.2 1.7 6.6 0.5 5.5 1 1 5 6 6 6 6 DNA polymerase phi DUF3106 PF11304.8 OWF40731.1 - 1.6e-05 25.3 0.1 20 5.7 0.0 3.8 1 1 1 3 3 3 1 Protein of unknown function (DUF3106) DUF3703 PF12487.8 OWF40731.1 - 0.01 15.7 24.0 1.6e+02 2.1 0.1 9.7 1 1 18 19 19 19 0 Protein of unknown function (DUF3703) SWIB PF02201.18 OWF40731.1 - 0.43 10.5 34.1 77 3.3 0.1 8.8 1 1 16 17 17 17 0 SWIB/MDM2 domain zf-C3HC4 PF00097.25 OWF40731.1 - 5.6 6.9 93.6 29 4.6 3.1 13.6 1 1 18 19 19 19 0 Zinc finger, C3HC4 type (RING finger) DUF2345 PF10106.9 OWF40732.1 - 3.3e-09 36.8 25.3 0.65 9.9 0.2 6.3 1 1 6 7 7 7 7 Uncharacterized protein conserved in bacteria (DUF2345) Cornifin PF02389.15 OWF40732.1 - 1.1e-05 25.6 53.1 0.13 12.4 15.6 3.2 1 1 2 3 3 3 3 Cornifin (SPRR) family HTH_54 PF18607.1 OWF40733.1 - 0.011 15.7 14.4 53 4.0 0.1 8.4 1 1 4 9 9 9 0 ParA helix turn helix domain Adhes-Ig_like PF09085.10 OWF40733.1 - 0.061 13.5 2.4 88 3.3 0.0 6.0 4 3 1 6 6 6 0 Adhesion molecule, immunoglobulin-like Lectin_like PF18560.1 OWF40733.1 - 2.1 8.5 25.6 11 6.1 0.5 5.8 1 1 3 6 6 6 0 Lectin like domain muHD PF10291.9 OWF40733.1 - 6.9 6.0 11.2 6.2 6.2 1.0 3.4 3 1 0 3 3 3 0 Muniscin C-terminal mu homology domain QIL1 PF15884.5 OWF40734.1 - 1.7e-13 51.0 0.5 9.3e-13 48.6 0.5 2.0 1 1 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 Galactosyl_T PF01762.21 OWF40735.1 - 1.7e-39 135.7 0.1 2.3e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase BshC PF10079.9 OWF40736.1 - 0.082 11.6 21.8 0.066 12.0 9.2 2.5 2 1 0 2 2 2 0 Bacillithiol biosynthesis BshC Arg_decarbox_C PF17944.1 OWF40736.1 - 0.32 11.6 4.1 0.74 10.4 0.2 3.4 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension G0-G1_switch_2 PF15103.6 OWF40736.1 - 0.38 11.2 0.0 0.38 11.2 0.0 2.8 1 1 1 2 2 2 0 G0/G1 switch protein 2 CheZ PF04344.13 OWF40736.1 - 2.8 7.8 17.6 0.08 12.9 2.5 3.2 2 1 1 3 3 3 0 Chemotaxis phosphatase, CheZ ApoO PF09769.9 OWF40736.1 - 8.9 6.3 5.9 8.2 6.4 0.2 3.1 2 1 1 3 3 3 0 Apolipoprotein O DUF126 PF01989.16 OWF40737.1 - 0.0002 21.1 29.2 36 4.2 0.1 13.3 1 1 19 22 22 22 1 Aconitase X swivel domain DUF2541 PF10807.8 OWF40737.1 - 0.0026 17.9 18.9 1.6 8.8 0.5 5.4 2 1 3 5 5 5 4 Protein of unknown function (DUF2541) DUF3213 PF11491.8 OWF40737.1 - 0.0093 16.1 1.2 92 3.3 0.0 5.5 4 2 4 8 8 8 0 Protein of unknown function (DUF3213) DUF3528 PF12045.8 OWF40737.1 - 0.055 14.1 11.3 56 4.4 0.1 6.8 1 1 4 7 7 7 0 Protein of unknown function (DUF3528) HHH_4 PF14490.6 OWF40738.1 - 0.057 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Hydantoinase_A PF01968.18 OWF40738.1 - 0.11 11.8 0.0 0.46 9.7 0.0 2.0 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase Glyco_hydro_20 PF00728.22 OWF40739.1 - 4e-189 628.4 0.0 2.1e-97 326.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 OWF40739.1 - 2.6e-60 202.7 0.0 3.4e-30 104.8 0.0 2.8 3 0 0 3 3 3 2 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 OWF40739.1 - 1.5e-42 143.4 0.1 4.6e-20 71.4 0.0 2.8 2 0 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 OWF40739.1 - 1.3e-27 97.0 2.0 1e-15 58.6 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OWF40739.1 - 0.0044 17.7 0.1 2.2 8.9 0.0 2.9 2 1 0 2 2 2 2 beta-acetyl hexosaminidase like zf-CW PF07496.15 OWF40740.1 - 1.2e-15 57.2 8.6 3.2e-15 55.9 8.6 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger Morc6_S5 PF17942.1 OWF40740.1 - 4.6e-15 55.9 0.1 1.9e-14 53.9 0.1 2.2 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like Uds1 PF15456.6 OWF40740.1 - 3.4 7.8 61.5 1.4 9.1 16.2 4.6 2 1 2 4 4 4 0 Up-regulated During Septation NifU_N PF01592.16 OWF40741.1 - 5.6e-58 194.7 0.2 6.5e-58 194.4 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Proteasome PF00227.26 OWF40741.1 - 0.033 13.7 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit zf-RING_14 PF17978.1 OWF40742.1 - 3e-36 123.7 2.6 3e-36 123.7 2.6 2.4 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_12 PF17976.1 OWF40742.1 - 3.8e-22 78.3 6.8 3.8e-22 78.3 6.8 2.9 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain ubiquitin PF00240.23 OWF40742.1 - 4.2e-12 45.6 0.0 7.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family IBR PF01485.21 OWF40742.1 - 0.0015 18.7 0.0 0.0015 18.7 0.0 4.5 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Rad60-SLD PF11976.8 OWF40742.1 - 0.0028 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Prok-RING_4 PF14447.6 OWF40742.1 - 0.0078 16.1 6.9 0.0078 16.1 6.9 3.7 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 DUF2407 PF10302.9 OWF40742.1 - 0.042 14.4 0.1 0.092 13.3 0.1 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OWF40742.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ATP1G1_PLM_MAT8 PF02038.16 OWF40742.1 - 0.19 11.2 1.4 0.59 9.6 0.1 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Morc6_S5 PF17942.1 OWF40743.1 - 9.9e-42 142.3 0.2 2.7e-41 140.9 0.2 1.8 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 OWF40743.1 - 9.8e-18 64.3 0.0 3.1e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.15 OWF40743.1 - 7.6e-17 61.1 5.8 1.6e-16 60.0 5.8 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c PF02518.26 OWF40743.1 - 1.2e-05 25.8 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TAXi_N PF14543.6 OWF40743.1 - 5.7 7.1 6.9 0.41 10.9 0.4 2.4 3 0 0 3 3 3 0 Xylanase inhibitor N-terminal SET PF00856.28 OWF40744.1 - 8.8e-09 36.0 0.1 1.4e-08 35.3 0.1 1.4 1 0 0 1 1 1 1 SET domain DNA_pol_B PF00136.21 OWF40745.1 - 1.2e-100 337.5 0.0 1.9e-100 336.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OWF40745.1 - 8.2e-21 74.5 0.0 3.2e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OWF40745.1 - 6e-13 49.1 9.0 6e-13 49.1 9.0 2.4 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF4683 PF15735.5 OWF40745.1 - 5.9e-05 22.9 17.7 6.7e-05 22.7 5.9 6.3 4 1 2 6 6 6 2 Domain of unknown function (DUF4683) DUF2150 PF09920.9 OWF40745.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) DSPc PF00782.20 OWF40746.1 - 3.1e-41 140.3 0.0 6.2e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 OWF40746.1 - 1.9e-07 31.5 0.0 5.6e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase PF00102.27 OWF40746.1 - 0.0052 16.4 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase phage_tail_N PF08400.10 OWF40748.1 - 0.017 15.1 0.0 17 5.4 0.0 3.7 1 1 3 4 4 4 0 Prophage tail fibre N-terminal STG PF15809.5 OWF40748.1 - 0.22 11.6 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Simian taste bud-specific gene product family FANCD2OS PF15124.6 OWF40748.1 - 3.8 7.7 4.2 31 4.7 0.0 2.9 2 1 1 3 3 3 0 FANCD2 opposite strand protein TspO_MBR PF03073.15 OWF40750.1 - 7.8e-50 168.4 13.3 8.8e-50 168.3 13.3 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF3925 PF13063.6 OWF40750.1 - 0.019 15.2 0.1 0.019 15.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) YBD PF17725.1 OWF40751.1 - 1.3e-97 325.7 0.8 1.7e-97 325.3 0.8 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 OWF40751.1 - 1.9e-27 95.1 0.0 4.5e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Pkinase PF00069.25 OWF40752.1 - 2.9e-61 207.2 0.4 4.5e-60 203.2 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40752.1 - 3.1e-27 95.5 0.1 7.1e-20 71.4 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF40752.1 - 3.3e-06 26.3 1.3 7.1e-06 25.2 1.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF40752.1 - 0.0059 16.6 0.4 0.039 13.9 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF40752.1 - 0.0079 15.5 0.1 0.046 13.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 OWF40752.1 - 0.009 15.0 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_C PF00433.24 OWF40752.1 - 0.015 16.0 1.8 0.14 12.9 1.8 2.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 OWF40752.1 - 0.057 12.5 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UPF0240 PF06784.11 OWF40753.1 - 1.4e-38 132.7 2.0 1.4e-38 132.7 2.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0240) ANTH PF07651.16 OWF40754.1 - 2.4e-77 259.7 0.0 3.3e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OWF40754.1 - 2.9e-12 46.7 0.4 7e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 ENTH domain OAD_gamma PF04277.13 OWF40755.1 - 0.0051 17.4 0.1 0.01 16.4 0.1 1.6 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain ETRAMP PF09716.10 OWF40755.1 - 0.071 13.2 0.6 0.071 13.2 0.6 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Osmo_CC PF08946.10 OWF40755.1 - 0.075 13.3 5.0 1.8 8.8 0.6 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil SIT PF15330.6 OWF40755.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3042 PF11240.8 OWF40755.1 - 5.9 7.0 11.1 1.1 9.3 0.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3042) CAP PF00188.26 OWF40756.1 - 3.7e-20 73.0 2.8 3.7e-20 73.0 2.8 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ShK PF01549.24 OWF40756.1 - 1.9e-11 44.3 33.0 3.5e-09 37.1 12.9 3.5 4 0 0 4 4 4 2 ShK domain-like Serglycin PF04360.12 OWF40756.1 - 7.3 6.5 10.2 20 5.1 10.2 1.8 1 1 0 1 1 1 0 Serglycin Hormone_recep PF00104.30 OWF40757.1 - 1.9e-38 132.2 0.0 3.2e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF40757.1 - 3.6e-31 107.4 16.5 6.1e-31 106.7 16.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_1 PF00130.22 OWF40757.1 - 5.8 6.9 8.9 0.44 10.5 1.3 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EST1_DNA_bind PF10373.9 OWF40758.1 - 5.5e-41 140.9 3.0 1.1e-40 140.0 3.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 OWF40758.1 - 4.8e-23 82.3 0.3 4.8e-23 82.3 0.3 2.8 3 0 0 3 3 3 1 Telomerase activating protein Est1 zf-AD PF07776.15 OWF40758.1 - 0.0043 17.3 0.4 0.017 15.3 0.4 2.1 1 1 0 1 1 1 1 Zinc-finger associated domain (zf-AD) Tyrosinase PF00264.20 OWF40759.1 - 8.4e-31 108.0 1.4 8.8e-15 55.6 0.1 2.5 1 1 1 2 2 2 2 Common central domain of tyrosinase Pex2_Pex12 PF04757.14 OWF40759.1 - 0.05 13.2 0.1 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region DUF4817 PF16087.5 OWF40759.1 - 0.93 9.3 2.9 0.43 10.4 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Glyco_transf_54 PF04666.13 OWF40760.1 - 4e-71 239.2 0.3 1.1e-70 237.8 0.3 1.6 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region F5_F8_type_C PF00754.25 OWF40760.1 - 0.057 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain Lectin_C PF00059.21 OWF40761.1 - 8.2e-05 23.3 3.3 2.1 9.1 0.0 4.2 2 2 0 3 3 3 2 Lectin C-type domain Vpu PF00558.19 OWF40761.1 - 0.0029 17.3 0.2 0.0051 16.6 0.2 1.4 1 0 0 1 1 1 1 Vpu protein Myc_target_1 PF15179.6 OWF40761.1 - 0.032 14.2 0.2 0.075 12.9 0.2 1.6 1 0 0 1 1 1 0 Myc target protein 1 FeoB_associated PF12669.7 OWF40761.1 - 0.08 13.4 4.0 0.23 11.9 4.0 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein LapA_dom PF06305.11 OWF40761.1 - 0.14 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2070 PF09843.9 OWF40761.1 - 0.15 10.3 0.2 0.21 9.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EphA2_TM PF14575.6 OWF40761.1 - 0.15 12.9 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Flagellar_put PF12611.8 OWF40762.1 - 0.0034 17.1 0.8 59 3.6 0.0 5.1 3 0 0 3 3 3 3 Putative flagellar DUF3693 PF12472.8 OWF40762.1 - 0.016 14.9 20.7 2.2 8.0 0.2 6.8 4 3 3 7 7 7 0 Phage related protein DUF2148 PF09918.9 OWF40762.1 - 0.084 12.9 5.1 78 3.4 0.0 5.0 4 1 1 5 5 5 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Kazal_1 PF00050.21 OWF40763.1 - 1.3e-07 31.5 5.5 1.7e-07 31.1 5.5 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF40763.1 - 6.1e-07 29.5 4.3 8.7e-07 29.0 4.3 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 OWF40764.1 - 3.2e-06 27.5 2.5 3.3e-05 24.2 0.3 2.7 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF40764.1 - 0.00099 18.9 3.1 0.0061 16.4 0.1 3.5 3 2 1 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 OWF40764.1 - 0.0081 15.6 1.8 0.028 14.0 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF40764.1 - 0.0088 15.9 0.5 0.027 14.3 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 OWF40764.1 - 0.13 12.2 0.6 5.1 7.0 0.1 2.8 2 1 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 OWF40764.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.8 3 0 0 3 3 3 0 EF hand SH2 PF00017.24 OWF40765.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 SH2 domain PRE_C2HC PF07530.11 OWF40765.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Associated with zinc fingers Peptidase_C50 PF03568.17 OWF40766.1 - 1.2e-89 301.2 1.4 3e-89 299.9 0.2 2.4 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 OWF40766.1 - 0.00015 21.3 0.0 0.002 17.6 0.0 2.4 1 1 0 1 1 1 1 CHAT domain LRR_9 PF14580.6 OWF40767.1 - 1.5e-12 47.4 0.5 2.5e-12 46.7 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF40767.1 - 3.9e-10 39.8 7.8 8e-06 26.1 1.0 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF40767.1 - 6.9e-09 35.4 0.7 2.8e-05 23.8 0.0 2.8 2 1 1 3 3 3 2 Leucine rich repeat SART-1 PF03343.13 OWF40767.1 - 0.002 16.8 0.0 0.002 16.8 0.0 2.1 2 0 0 2 2 2 1 SART-1 family zf-CCCH PF00642.24 OWF40768.1 - 2.7e-11 43.1 34.0 1.9e-05 24.4 2.0 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CHY PF05495.12 OWF40768.1 - 2.2e-09 37.7 16.6 2.2e-09 37.7 16.6 5.3 4 1 2 6 6 6 1 CHY zinc finger zf-CCCH_4 PF18044.1 OWF40768.1 - 3e-09 36.5 29.5 2.6e-07 30.3 5.5 4.6 5 0 0 5 5 5 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OWF40768.1 - 2e-06 27.7 46.5 0.003 17.5 7.6 4.1 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH_2 PF14608.6 OWF40768.1 - 1.4e-05 25.4 28.8 0.019 15.5 5.2 3.9 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OWF40768.1 - 2.8e-05 24.8 0.8 2.8e-05 24.8 0.8 4.1 2 1 2 4 4 4 3 Torus domain DNA_pol_phi PF04931.13 OWF40768.1 - 8 4.4 7.5 11 3.9 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi HSP70 PF00012.20 OWF40769.1 - 1.9e-09 36.3 0.5 3.5e-08 32.1 0.5 2.3 1 1 0 1 1 1 1 Hsp70 protein DDR PF08841.10 OWF40769.1 - 0.017 14.2 2.6 0.22 10.5 0.2 2.9 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain DUF520 PF04461.13 OWF40769.1 - 0.079 13.1 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Rad9_Rad53_bind PF08605.10 OWF40769.1 - 0.085 13.1 0.1 0.84 9.8 0.0 2.5 3 0 0 3 3 3 0 Fungal Rad9-like Rad53-binding HSP70 PF00012.20 OWF40770.1 - 4.9e-10 38.2 1.4 9.3e-09 34.0 0.5 2.7 2 1 0 2 2 2 1 Hsp70 protein DDR PF08841.10 OWF40770.1 - 0.0046 16.0 2.7 0.19 10.7 0.1 3.1 3 1 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain DUF520 PF04461.13 OWF40770.1 - 0.031 14.4 1.0 0.059 13.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF520) p450 PF00067.22 OWF40771.1 - 3.6e-71 240.3 0.0 4.3e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF40772.1 - 3.7e-63 213.9 0.0 4.3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.22 OWF40773.1 - 9.8e-31 107.6 0.0 1.7e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain DED PF01335.21 OWF40773.1 - 0.01 16.1 0.3 0.026 14.8 0.3 1.7 1 0 0 1 1 1 0 Death effector domain TACC_C PF05010.14 OWF40773.1 - 0.096 12.5 1.0 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal adh_short PF00106.25 OWF40774.1 - 2.6e-34 118.4 0.0 1.3e-27 96.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF40774.1 - 4.7e-26 91.8 0.0 3.1e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF40774.1 - 1.4e-09 38.1 0.0 2.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF40774.1 - 4.6e-05 23.0 0.0 7.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF40774.1 - 0.02 14.3 0.0 0.02 14.3 0.0 1.9 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase CDC27 PF09507.10 OWF40774.1 - 0.45 9.8 36.7 0.69 9.2 36.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TRAM_LAG1_CLN8 PF03798.16 OWF40775.1 - 9.9e-42 142.9 31.1 1.4e-41 142.4 31.1 1.2 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 OWF40775.1 - 1.4e-08 34.4 0.5 2.9e-08 33.4 0.5 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF40775.1 - 0.0048 16.3 0.0 0.0097 15.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF40775.1 - 0.06 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain TRAM_LAG1_CLN8 PF03798.16 OWF40776.1 - 3e-34 118.5 30.3 3e-34 118.5 30.3 1.8 2 0 0 2 2 2 1 TLC domain Homeodomain PF00046.29 OWF40776.1 - 2.4e-05 24.1 0.2 4.1e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF40776.1 - 0.053 13.4 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain FAM176 PF14851.6 OWF40776.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 FAM176 family RRM_1 PF00076.22 OWF40777.1 - 1.4e-17 63.2 0.5 2.3e-17 62.6 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF40777.1 - 0.00031 20.8 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 OWF40777.1 - 0.026 14.6 0.2 0.045 13.8 0.2 1.3 1 0 0 1 1 1 0 RNA binding motif Thioredoxin PF00085.20 OWF40778.1 - 2.6e-91 300.4 0.2 2.7e-32 110.8 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 OWF40778.1 - 1.6e-25 90.1 7.0 4.7e-20 72.3 0.9 4.2 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OWF40778.1 - 2.6e-15 56.8 1.1 2.1e-05 24.9 0.0 5.4 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OWF40778.1 - 4.9e-15 55.5 0.0 0.0011 19.1 0.0 4.5 4 0 0 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 OWF40778.1 - 2.7e-14 53.2 0.1 0.0066 15.8 0.1 4.3 2 2 2 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OWF40778.1 - 4.3e-13 49.4 0.1 0.044 14.1 0.0 5.7 4 2 2 6 6 6 3 Thioredoxin-like AhpC-TSA PF00578.21 OWF40778.1 - 1.4e-11 44.4 0.9 0.084 12.8 0.0 5.3 5 1 1 6 6 6 3 AhpC/TSA family Calsequestrin PF01216.17 OWF40778.1 - 8.4e-08 31.6 4.0 1.9e-06 27.2 1.4 2.4 1 1 0 2 2 2 1 Calsequestrin HyaE PF07449.11 OWF40778.1 - 2.2e-06 27.6 0.1 0.15 12.0 0.0 4.2 5 0 0 5 5 5 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 OWF40778.1 - 3.6e-05 23.5 0.2 0.38 10.4 0.0 3.6 3 0 0 3 3 3 1 Redoxin Glyco_hydro_72 PF03198.14 OWF40778.1 - 0.00072 18.9 0.0 1.1 8.5 0.0 3.1 2 1 1 3 3 3 2 Glucanosyltransferase Thioredoxin_4 PF13462.6 OWF40778.1 - 0.045 13.9 1.9 47 4.1 0.1 3.8 3 1 0 3 3 3 0 Thioredoxin Aldedh PF00171.22 OWF40779.1 - 7.3e-172 572.0 0.1 9.1e-172 571.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF PF00209.18 OWF40780.1 - 5e-171 569.9 39.5 1.5e-169 565.1 39.5 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Gate PF07670.14 OWF40780.1 - 0.35 11.2 9.1 4 7.8 3.5 2.9 2 0 0 2 2 2 0 Nucleoside recognition Fer4_24 PF18109.1 OWF40780.1 - 0.68 10.3 1.8 2.1 8.7 0.0 2.4 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain Phage_holin_2_4 PF16082.5 OWF40780.1 - 1.3 8.8 3.1 4.9 7.0 0.2 2.8 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 OWF40781.1 - 4.1e-13 49.0 14.0 3.2e-08 32.9 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OWF40781.1 - 0.0047 15.3 0.5 1.4 7.1 0.0 2.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Speriolin_C PF15059.6 OWF40782.1 - 7.5e-37 126.7 0.4 1.7e-36 125.6 0.1 1.8 2 0 0 2 2 2 1 Speriolin C-terminus PikAIV_N PF18605.1 OWF40782.1 - 0.31 10.6 5.5 0.86 9.2 4.4 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Fez1 PF06818.15 OWF40783.1 - 6.1e-07 30.1 374.8 0.032 14.7 10.4 18.6 1 1 21 22 22 22 11 Fez1 CALCOCO1 PF07888.11 OWF40783.1 - 0.00033 19.7 40.6 0.00033 19.7 40.6 11.7 1 1 10 11 11 11 2 Calcium binding and coiled-coil domain (CALCOCO1) like Mod_r PF07200.13 OWF40783.1 - 0.00046 20.3 4.9 0.00046 20.3 4.9 23.0 2 1 18 21 21 21 2 Modifier of rudimentary (Mod(r)) protein Tropomyosin PF00261.20 OWF40783.1 - 0.00071 19.0 13.0 0.00071 19.0 13.0 17.1 2 1 13 15 15 15 5 Tropomyosin ATG16 PF08614.11 OWF40783.1 - 0.0016 18.7 425.8 0.029 14.6 21.0 22.1 2 1 19 21 21 21 9 Autophagy protein 16 (ATG16) BST2 PF16716.5 OWF40783.1 - 0.007 16.9 4.7 0.007 16.9 4.7 28.6 8 5 22 31 31 31 10 Bone marrow stromal antigen 2 DUF4094 PF13334.6 OWF40783.1 - 0.35 11.3 0.0 0.35 11.3 0.0 22.5 4 2 12 20 20 20 0 Domain of unknown function (DUF4094) Sas6_CC PF18594.1 OWF40783.1 - 0.98 9.3 5.6 11 5.8 0.1 5.4 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain Golgin_A5 PF09787.9 OWF40783.1 - 3.7 6.9 416.7 0.02 14.4 20.4 18.6 1 1 18 20 20 20 0 Golgin subfamily A member 5 GSK-3_bind PF05350.12 OWF40784.1 - 0.21 10.9 1.4 0.44 9.8 0.3 1.8 1 1 1 2 2 2 0 Glycogen synthase kinase-3 binding Fucokinase PF07959.12 OWF40786.1 - 1.2e-73 248.4 0.0 1.7e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 OWF40786.1 - 2.5e-07 30.8 0.7 2.5e-07 30.8 0.7 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OWF40786.1 - 9e-05 22.8 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4783 PF16022.5 OWF40787.1 - 1.1 9.5 5.2 11 6.2 0.2 3.7 1 1 2 4 4 4 0 Domain of unknown function (DUF4783) P22_portal PF16510.5 OWF40787.1 - 2 6.9 4.8 2.9 6.4 3.9 1.5 1 1 1 2 2 2 0 Phage P22-like portal protein Furin-like_2 PF15913.5 OWF40787.1 - 3 8.0 14.3 13 6.0 4.3 3.1 1 1 2 3 3 3 0 Furin-like repeat, cysteine-rich zf-primase PF09329.11 OWF40788.1 - 8.8e-08 31.8 33.5 7.7 6.4 0.1 12.1 2 2 11 13 13 13 10 Primase zinc finger DHHC PF01529.20 OWF40789.1 - 1.3e-32 112.8 9.4 1.3e-32 112.8 9.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase UL42 PF17638.2 OWF40789.1 - 2.7 8.0 6.2 0.66 10.0 0.5 2.8 3 0 0 3 3 3 0 HCMV UL42 SR-25 PF10500.9 OWF40789.1 - 8.9 5.9 27.5 7.5 6.1 8.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA PF00004.29 OWF40790.1 - 5e-31 107.9 0.0 7.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF40790.1 - 4.9e-08 33.3 0.5 2.9e-07 30.8 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OWF40790.1 - 1.2e-06 29.1 0.0 2.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OWF40790.1 - 1e-05 26.0 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OWF40790.1 - 4.3e-05 23.6 0.0 9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OWF40790.1 - 8e-05 22.3 0.1 0.093 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OWF40790.1 - 0.00034 20.4 0.0 0.00073 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF40790.1 - 0.00051 20.2 0.0 0.00084 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OWF40790.1 - 0.00083 19.1 0.0 0.0028 17.4 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 OWF40790.1 - 0.0015 18.3 0.1 0.0088 15.8 0.1 2.1 2 1 0 2 2 2 1 Cytidylate kinase NACHT PF05729.12 OWF40790.1 - 0.0016 18.4 0.3 0.0082 16.1 0.3 2.0 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 OWF40790.1 - 0.0017 18.7 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 OWF40790.1 - 0.0017 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OWF40790.1 - 0.0021 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 OWF40790.1 - 0.0023 17.9 0.5 1.8 8.4 0.0 2.3 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea TsaE PF02367.17 OWF40790.1 - 0.0024 17.9 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OWF40790.1 - 0.0035 17.3 0.1 0.0076 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OWF40790.1 - 0.004 17.4 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 OWF40790.1 - 0.0041 16.4 0.5 0.61 9.3 0.2 2.2 1 1 1 2 2 2 1 KAP family P-loop domain AAA_11 PF13086.6 OWF40790.1 - 0.0048 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OWF40790.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 OWF40790.1 - 0.0075 15.6 0.6 0.97 8.7 0.0 2.3 1 1 1 2 2 2 1 KaiC DUF815 PF05673.13 OWF40790.1 - 0.0076 15.4 0.1 0.027 13.7 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 OWF40790.1 - 0.0079 16.7 0.0 0.048 14.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 OWF40790.1 - 0.0092 15.9 0.3 0.03 14.3 0.2 2.0 2 1 0 2 2 2 1 Rad17 P-loop domain PduV-EutP PF10662.9 OWF40790.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 OWF40790.1 - 0.014 15.7 0.0 0.072 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OWF40790.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OWF40790.1 - 0.016 14.6 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 OWF40790.1 - 0.018 15.5 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OWF40790.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 OWF40790.1 - 0.027 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 OWF40790.1 - 0.042 13.1 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 OWF40790.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OWF40790.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Gal-3-0_sulfotr PF06990.11 OWF40791.1 - 4.2e-40 137.9 1.0 4.2e-40 137.9 1.0 1.3 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF40791.1 - 0.0011 18.9 0.8 0.0023 17.9 0.1 1.8 2 0 0 2 2 2 1 Sulfotransferase family SQS_PSY PF00494.19 OWF40792.1 - 2.2e-60 204.4 0.0 2.7e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase cNMP_binding PF00027.29 OWF40793.1 - 1.2e-09 38.1 0.0 2.2e-07 30.8 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain DUF1279 PF06916.13 OWF40794.1 - 1.1e-23 83.5 0.7 2.3e-23 82.6 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Presenilin PF01080.17 OWF40794.1 - 0.018 13.9 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Presenilin GCV_T PF01571.21 OWF40794.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain GST_C_3 PF14497.6 OWF40795.1 - 5.4e-19 68.2 0.0 8.4e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF40795.1 - 1.4e-10 41.4 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF40795.1 - 1.3e-06 28.6 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF40795.1 - 0.0002 21.7 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF40795.1 - 0.032 14.5 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF40795.1 - 0.06 14.1 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 OWF40795.1 - 0.14 12.4 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin GST_C_3 PF14497.6 OWF40796.1 - 4.1e-21 75.0 0.3 5.9e-21 74.5 0.3 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF40796.1 - 4.7e-10 39.7 0.0 1.2e-07 31.9 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF40796.1 - 3.7e-08 33.5 0.1 5.8e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF40796.1 - 0.0018 18.6 0.0 0.0086 16.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF40796.1 - 0.02 15.2 0.0 0.093 13.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF40796.1 - 0.05 14.4 0.0 0.088 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 OWF40797.1 - 4.4e-21 74.9 0.2 9.5e-21 73.9 0.2 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF40797.1 - 1.7e-13 50.7 0.1 9.8e-13 48.3 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF40797.1 - 4.6e-09 36.4 0.1 9e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF40797.1 - 1.5e-06 28.5 0.0 4.2e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF40797.1 - 0.00027 21.6 0.0 0.00059 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 OWF40797.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF40797.1 - 0.0029 17.9 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 OWF40797.1 - 0.006 16.9 0.0 0.0096 16.2 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein MATH PF00917.26 OWF40798.1 - 0.015 15.5 0.2 0.099 12.8 0.3 2.1 2 0 0 2 2 2 0 MATH domain Cul7 PF11515.8 OWF40798.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 Glyco_transf_11 PF01531.16 OWF40799.1 - 0.00019 20.7 0.0 0.0012 18.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 11 XG_FTase PF03254.13 OWF40799.1 - 0.012 14.3 0.6 0.053 12.1 0.6 2.0 2 1 0 2 2 2 0 Xyloglucan fucosyltransferase Epimerase PF01370.21 OWF40800.1 - 8.8e-32 110.5 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF40800.1 - 2.1e-24 86.5 0.0 3.9e-24 85.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OWF40800.1 - 1.4e-15 57.2 0.0 1.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OWF40800.1 - 2.2e-14 53.1 0.0 3.3e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OWF40800.1 - 2.3e-10 40.1 0.0 8.9e-10 38.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OWF40800.1 - 1.6e-07 30.8 0.0 0.00012 21.4 0.0 2.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OWF40800.1 - 0.0028 17.6 0.0 0.0073 16.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 OWF40800.1 - 0.0028 17.1 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 OWF40800.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 OWF40800.1 - 0.14 12.0 1.9 0.66 9.9 0.7 2.5 2 1 0 2 2 2 0 KR domain GST_N_3 PF13417.6 OWF40801.1 - 8.9e-13 48.5 0.0 2.5e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF40801.1 - 2e-07 31.2 0.0 5.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF40801.1 - 4.5e-06 26.9 0.0 3.8e-05 23.9 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF40801.1 - 1.5e-05 24.9 0.1 0.00021 21.2 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF40801.1 - 0.0012 19.0 0.1 0.0026 17.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4455 PF14643.6 OWF40801.1 - 0.018 13.7 0.3 0.027 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Tom37 PF10568.9 OWF40801.1 - 0.048 14.0 1.2 0.13 12.6 0.0 2.2 3 0 0 3 3 3 0 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 OWF40801.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1640 PF07798.11 OWF40801.1 - 0.099 12.7 0.4 3.2 7.8 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Kdo PF06293.14 OWF40802.1 - 1.8e-09 37.3 0.0 3.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OWF40802.1 - 7.2e-08 32.1 0.4 1.4e-07 31.2 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain DUF1679 PF07914.11 OWF40802.1 - 4.2e-05 22.6 0.2 6.6e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 OWF40802.1 - 0.00031 20.4 0.1 0.00057 19.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OWF40802.1 - 0.00036 20.5 0.0 0.0012 18.8 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OWF40802.1 - 0.0024 17.2 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 OWF40802.1 - 0.0049 16.2 0.5 0.0086 15.4 0.2 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase DUF3512 PF12024.8 OWF40802.1 - 0.072 12.6 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) DUF883 PF05957.13 OWF40803.1 - 0.067 13.8 0.1 0.32 11.6 0.1 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ADH_N PF08240.12 OWF40804.1 - 2.1e-29 101.6 1.1 5e-29 100.4 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OWF40804.1 - 5.2e-21 75.0 0.1 9.3e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OWF40804.1 - 1.7e-12 47.3 0.7 5.8e-12 45.6 0.7 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OWF40804.1 - 3.6e-05 23.2 0.0 0.00049 19.5 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OWF40804.1 - 0.17 12.9 0.0 0.29 12.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF40805.1 - 4.8e-29 100.4 2.1 4.8e-29 100.4 2.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OWF40805.1 - 2.1e-22 79.5 0.2 1.1e-21 77.2 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OWF40805.1 - 9.9e-13 48.1 0.8 4.1e-12 46.0 0.8 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OWF40805.1 - 5.8e-06 25.7 0.2 9.3e-06 25.1 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-CXXC PF02008.20 OWF40805.1 - 0.0093 16.0 2.6 0.029 14.4 2.6 1.8 1 0 0 1 1 1 1 CXXC zinc finger domain UDPG_MGDP_dh_N PF03721.14 OWF40805.1 - 0.037 13.6 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HEPN PF05168.14 OWF40806.1 - 3.1e-12 46.7 0.0 1.5e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 HEPN domain HATPase_c_3 PF13589.6 OWF40808.1 - 0.022 14.6 0.7 0.42 10.4 0.7 2.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OWF40809.1 - 0.011 15.6 1.5 0.93 9.3 0.1 2.6 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ADH_N PF08240.12 OWF40810.1 - 6e-28 96.9 1.8 1e-27 96.2 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F5_F8_type_C PF00754.25 OWF40811.1 - 4.5e-11 43.0 4.2 6.2e-11 42.5 4.2 1.2 1 0 0 1 1 1 1 F5/8 type C domain ISK_Channel PF02060.15 OWF40812.1 - 0.034 13.9 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Laminin_EGF PF00053.24 OWF40814.1 - 2e-123 402.4 391.3 1.5e-10 41.1 11.5 20.3 20 1 1 21 21 20 19 Laminin EGF domain Laminin_G_1 PF00054.23 OWF40814.1 - 4.5e-96 318.1 0.6 1.8e-18 67.0 0.0 5.6 5 0 0 5 5 5 5 Laminin G domain Laminin_G_2 PF02210.24 OWF40814.1 - 2.2e-92 306.2 1.3 3.1e-20 73.0 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 OWF40814.1 - 6.5e-68 228.8 0.0 6.5e-68 228.8 0.0 4.2 4 0 0 4 4 2 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 OWF40814.1 - 2.5e-53 179.6 0.2 2.4e-27 95.5 0.0 2.5 2 0 0 2 2 2 2 Laminin B (Domain IV) Laminin_G_3 PF13385.6 OWF40814.1 - 9.6e-15 55.0 0.8 0.00011 22.4 0.0 5.5 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily Laminin_I PF06008.14 OWF40814.1 - 2.1e-10 40.7 7.7 2.1e-10 40.7 7.7 3.8 1 1 3 4 4 4 1 Laminin Domain I Laminin_II PF06009.12 OWF40814.1 - 1.1e-06 28.7 13.3 1.1e-06 28.7 13.3 4.9 3 2 2 5 5 5 1 Laminin Domain II Nup54 PF13874.6 OWF40814.1 - 0.12 12.4 25.3 0.088 12.9 0.5 4.5 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 LMBR1 PF04791.16 OWF40814.1 - 4 6.2 19.0 0.91 8.4 8.4 2.4 2 1 0 2 2 2 0 LMBR1-like membrane protein DHR10 PF18595.1 OWF40814.1 - 6.5 6.9 30.5 2.5 8.2 3.4 4.5 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain KxDL PF10241.9 OWF40814.1 - 8 6.8 20.4 0.12 12.7 1.4 4.5 5 0 0 5 5 5 0 Uncharacterized conserved protein Tctex-1 PF03645.13 OWF40815.1 - 4.1e-27 94.4 0.2 6.5e-27 93.8 0.2 1.3 1 0 0 1 1 1 1 Tctex-1 family SCVP PF17619.2 OWF40816.1 - 0.099 13.5 0.0 0.3 12.0 0.0 1.8 1 0 0 1 1 1 0 Secreted clade V proteins HABP4_PAI-RBP1 PF04774.15 OWF40817.1 - 1.2e-27 97.0 16.1 1.2e-27 97.0 16.1 4.3 4 1 0 4 4 4 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 OWF40817.1 - 1.7e-12 48.3 20.8 1.7e-12 48.3 20.8 3.2 2 1 1 3 3 3 1 Intracellular hyaluronan-binding protein 4 N-terminal IF-2B PF01008.17 OWF40818.1 - 1.3e-72 244.4 0.8 1.3e-72 244.4 0.8 1.5 2 0 0 2 2 2 1 Initiation factor 2 subunit family SET PF00856.28 OWF40819.1 - 0.039 14.4 0.1 0.35 11.2 0.0 2.2 2 1 0 3 3 3 0 SET domain DUF3514 PF12027.8 OWF40820.1 - 0.021 14.5 1.5 5.4 6.7 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3514) BDV_G PF06208.11 OWF40820.1 - 0.021 14.0 3.0 1 8.4 0.2 2.6 1 1 2 3 3 3 0 Borna disease virus G protein Tctex-1 PF03645.13 OWF40822.1 - 4.6e-26 91.0 0.8 6.4e-26 90.6 0.8 1.2 1 0 0 1 1 1 1 Tctex-1 family rRNA_proc-arch PF13234.6 OWF40823.1 - 3.1e-84 283.1 1.2 3.1e-84 283.1 1.2 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 OWF40823.1 - 8e-54 181.7 0.9 2.7e-53 180.0 0.9 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 OWF40823.1 - 2.2e-17 63.4 0.0 4.8e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF40823.1 - 6e-06 26.6 0.0 2.6e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF40823.1 - 0.00063 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF40823.1 - 0.057 13.7 0.0 0.33 11.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 OWF40823.1 - 0.14 12.1 1.0 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea HCO3_cotransp PF00955.21 OWF40824.1 - 2.2e-167 557.9 7.4 3.3e-167 557.4 7.4 1.2 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 OWF40824.1 - 6.6e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Sulfate_transp PF00916.20 OWF40824.1 - 0.0033 16.2 5.7 0.37 9.5 0.2 2.5 2 0 0 2 2 2 2 Sulfate permease family muHD PF10291.9 OWF40825.1 - 3.4e-57 193.9 0.1 1e-56 192.3 0.0 1.7 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.23 OWF40825.1 - 4.5e-13 49.3 1.8 1.8e-12 47.3 0.0 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Prominin PF05478.11 OWF40825.1 - 0.11 10.5 4.9 0.16 9.9 4.9 1.1 1 0 0 1 1 1 0 Prominin NHL PF01436.21 OWF40826.1 - 6.1e-15 54.4 3.6 0.021 14.8 0.1 5.9 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 OWF40826.1 - 1.3e-05 24.9 0.3 0.053 13.1 0.0 4.1 2 1 2 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4 PF00097.25 OWF40826.1 - 2.6e-05 24.0 9.9 2.6e-05 24.0 9.9 3.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF40826.1 - 8.9e-05 22.6 26.3 0.00062 19.9 5.9 3.7 4 0 0 4 4 2 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF40826.1 - 0.00015 21.7 6.6 0.00015 21.7 6.6 3.0 3 1 1 4 4 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF40826.1 - 0.0012 18.8 9.7 0.0012 18.8 9.7 3.9 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF40826.1 - 0.0027 17.8 12.2 0.0027 17.8 12.2 3.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF40826.1 - 0.0042 17.4 10.0 0.0042 17.4 10.0 3.7 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF40826.1 - 0.013 15.3 11.5 0.013 15.3 11.5 3.6 3 2 0 3 3 1 0 Zinc finger, C3HC4 type (RING finger) WEMBL PF05701.11 OWF40826.1 - 0.015 14.0 2.9 0.025 13.3 2.9 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Prominin PF05478.11 OWF40826.1 - 0.029 12.4 6.0 0.041 11.8 6.0 1.2 1 0 0 1 1 1 0 Prominin HBM PF16591.5 OWF40826.1 - 0.031 13.7 0.3 0.053 12.9 0.3 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain ApoLp-III PF07464.11 OWF40826.1 - 0.049 13.7 0.3 0.13 12.3 0.3 1.7 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ADIP PF11559.8 OWF40826.1 - 0.071 13.2 0.3 0.071 13.2 0.3 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 OWF40826.1 - 0.077 13.0 4.9 0.07 13.2 1.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Ldl_recept_b PF00058.17 OWF40826.1 - 0.093 13.2 0.4 0.23 11.9 0.1 1.9 2 0 0 2 2 1 0 Low-density lipoprotein receptor repeat class B Reg_prop PF07494.11 OWF40826.1 - 0.19 12.1 1.3 2.4 8.7 0.0 3.3 3 0 0 3 3 2 0 Two component regulator propeller Snf7 PF03357.21 OWF40826.1 - 0.34 10.5 3.9 0.53 9.9 2.8 1.8 2 0 0 2 2 2 0 Snf7 ELO PF01151.18 OWF40827.1 - 2.7e-64 217.1 29.6 3.2e-64 216.9 29.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 OWF40827.1 - 0.078 13.2 3.6 25 5.1 0.2 3.7 3 0 0 3 3 3 0 CCSMST1 family NDUF_B7 PF05676.13 OWF40828.1 - 1.9e-23 82.0 3.9 2.4e-23 81.6 3.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 OWF40828.1 - 0.058 13.4 5.6 0.09 12.8 5.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.32 OWF40829.1 - 6.8e-27 93.2 3.0 1.4e-06 28.9 1.0 6.3 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF40829.1 - 1.2e-13 51.1 0.1 0.003 17.8 0.0 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF40829.1 - 0.00025 20.5 0.6 0.024 14.0 0.1 2.8 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 OWF40829.1 - 0.00034 19.7 1.1 3 6.7 0.0 3.1 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OWF40829.1 - 0.0021 16.8 0.8 0.057 12.0 0.3 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 CLAMP PF14769.6 OWF40830.1 - 1.9e-07 31.5 7.8 2.2e-06 28.0 4.9 3.2 2 1 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 Orthopox_B11R PF07033.11 OWF40830.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus B11R protein PLAT PF01477.23 OWF40831.1 - 0 1016.8 72.9 7.1e-20 71.7 0.0 21.2 21 0 0 21 21 21 21 PLAT/LH2 domain DCX PF03607.17 OWF40831.1 - 6.7e-24 83.8 0.1 7.2e-12 45.2 0.1 3.3 3 0 0 3 3 3 2 Doublecortin Lactamase_B_5 PF14597.6 OWF40831.1 - 0.3 10.5 1.9 13 5.2 0.0 3.6 4 0 0 4 4 4 0 Metallo-beta-lactamase superfamily SPATA6 PF14909.6 OWF40832.1 - 8.1e-49 165.3 0.0 1.2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 DUF1754 PF08555.10 OWF40833.1 - 1.2e-07 32.4 20.8 1.4e-06 29.0 20.8 2.1 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SpoIIP PF07454.11 OWF40833.1 - 0.061 12.8 5.8 0.071 12.6 5.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Sas10 PF09368.10 OWF40834.1 - 1.6e-26 92.5 12.6 1.6e-26 92.5 12.6 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OWF40834.1 - 3e-12 47.0 0.1 3e-12 47.0 0.1 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Pkinase_Tyr PF07714.17 OWF40835.1 - 1e-97 326.5 0.0 1.3e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF40835.1 - 3e-50 171.1 0.0 4.1e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF40835.1 - 6e-26 90.3 0.3 1.3e-25 89.2 0.3 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 OWF40835.1 - 1.5e-17 62.9 0.2 4.9e-17 61.3 0.1 2.0 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 OWF40835.1 - 1.8e-12 46.9 0.1 8.1e-12 44.8 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OWF40835.1 - 8e-09 35.1 0.0 8.4e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 OWF40835.1 - 5.4e-06 25.6 0.0 9.5e-06 24.8 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF40835.1 - 0.007 16.3 0.0 0.16 11.9 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family SH3_3 PF08239.11 OWF40835.1 - 0.029 14.6 0.1 0.12 12.6 0.2 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain B2 PF11473.8 OWF40835.1 - 0.031 14.1 0.1 0.44 10.4 0.1 2.2 2 0 0 2 2 2 0 RNA binding protein B2 Kdo PF06293.14 OWF40835.1 - 0.056 12.8 0.1 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OWF40836.1 - 5.8e-27 94.1 0.5 1.6e-09 38.2 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF40836.1 - 4.3e-24 84.6 1.0 7.7e-10 39.1 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF40836.1 - 2.7e-21 75.3 0.5 1.2e-08 35.0 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF40836.1 - 1.8e-18 64.7 0.1 1.3e-06 28.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OWF40836.1 - 2e-17 62.8 0.9 1.3e-08 34.9 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat KN_motif PF12075.8 OWF40836.1 - 1e-09 38.1 0.5 3e-09 36.5 0.2 2.0 2 0 0 2 2 2 1 KN motif Isy1 PF06246.12 OWF40837.1 - 1.7e-08 34.3 3.6 1.7e-08 34.3 3.6 1.5 1 1 0 1 1 1 1 Isy1-like splicing family Arm-DNA-bind_5 PF17293.2 OWF40837.1 - 0.54 10.7 4.9 3.6 8.1 0.1 2.6 1 1 1 2 2 2 0 Arm DNA-binding domain MFS_1 PF07690.16 OWF40838.1 - 8.9e-22 77.5 33.7 1.7e-13 50.3 22.5 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2530 PF10745.9 OWF40838.1 - 3.4 8.0 9.5 0.17 12.1 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 OWF40839.1 - 5.5e-17 61.7 41.4 6.3e-16 58.2 41.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily CtIP_N PF10482.9 OWF40840.1 - 0.0063 16.5 16.9 1.6 8.8 0.4 4.8 1 1 1 4 4 4 3 Tumour-suppressor protein CtIP N-terminal domain DUF4201 PF13870.6 OWF40840.1 - 0.014 15.1 4.0 1.3 8.8 0.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) WbqC PF08889.11 OWF40840.1 - 0.033 14.1 6.5 25 4.7 0.0 5.9 1 1 9 11 11 11 0 WbqC-like protein family DUF2125 PF09898.9 OWF40840.1 - 0.056 13.1 0.3 8.4 6.0 0.0 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2125) Phage_T4_Ndd PF06591.11 OWF40840.1 - 0.058 13.2 7.4 25 4.7 0.0 5.6 3 2 4 7 7 7 0 T4-like phage nuclear disruption protein (Ndd) Neural_ProG_Cyt PF06567.11 OWF40840.1 - 0.21 11.8 7.0 11 6.3 0.1 4.5 2 1 1 6 6 6 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain HNH_3 PF13392.6 OWF40840.1 - 0.5 10.2 20.9 16 5.3 0.1 6.8 6 0 0 6 6 6 0 HNH endonuclease AP-5_subunit_s1 PF15001.6 OWF40840.1 - 0.69 9.9 2.3 35 4.3 0.0 3.5 2 1 3 5 5 5 0 AP-5 complex subunit sigma-1 TIP39 PF14980.6 OWF40840.1 - 1.6 8.7 17.2 1.4e+02 2.4 0.0 8.1 11 0 0 11 11 11 0 TIP39 peptide TFIIF_alpha PF05793.12 OWF40841.1 - 3e-119 399.0 75.9 9.8e-119 397.3 75.9 1.6 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cytomega_TRL10 PF06084.11 OWF40841.1 - 1.6 8.8 4.8 4.3 7.4 4.8 1.7 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein F-box-like PF12937.7 OWF40842.1 - 3.2e-14 52.5 0.5 8.1e-14 51.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OWF40842.1 - 6.4e-10 38.7 0.3 1.6e-09 37.4 0.3 1.7 1 0 0 1 1 1 1 F-box domain Arf PF00025.21 OWF40842.1 - 4.5e-09 36.0 0.0 7.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PRANC PF09372.10 OWF40842.1 - 0.0003 21.1 0.1 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 PRANC domain F-box_4 PF15966.5 OWF40842.1 - 0.042 13.7 0.5 0.16 11.9 0.3 2.2 3 0 0 3 3 3 0 F-box Ank_2 PF12796.7 OWF40844.1 - 2.7e-16 59.9 0.2 8.4e-11 42.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF40844.1 - 6.9e-13 48.8 0.2 4.5e-08 33.5 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF40844.1 - 1.8e-11 44.0 0.1 2.2e-05 24.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF40844.1 - 3.4e-10 39.3 0.4 0.0097 16.3 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OWF40844.1 - 1.1e-08 35.1 0.1 0.02 15.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Lant_dehydr_C PF14028.6 OWF40844.1 - 0.65 9.5 5.2 0.2 11.2 0.5 2.0 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Spt20 PF12090.8 OWF40844.1 - 3.7 7.1 25.2 7.1 6.2 25.2 1.4 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 OWF40844.1 - 7.9 5.2 16.6 12 4.6 16.6 1.2 1 0 0 1 1 1 0 Androgen receptor RR_TM4-6 PF06459.12 OWF40844.1 - 9.4 6.0 10.6 18 5.1 10.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WW PF00397.26 OWF40845.1 - 0.0021 18.1 0.1 0.0048 17.0 0.1 1.7 1 0 0 1 1 1 1 WW domain BUD22 PF09073.10 OWF40845.1 - 0.074 12.4 26.1 0.13 11.6 26.1 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 OWF40845.1 - 0.77 9.3 28.6 0.05 13.2 23.1 1.9 2 0 0 2 2 2 0 PPP4R2 NOA36 PF06524.12 OWF40845.1 - 0.94 8.7 21.6 1.5 8.0 21.6 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OWF40845.1 - 2.6 6.1 24.1 2 6.4 19.3 2.9 3 1 0 3 3 3 0 DNA polymerase phi CDC45 PF02724.14 OWF40845.1 - 5.7 5.1 16.5 9.2 4.4 16.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TIR_2 PF13676.6 OWF40846.1 - 8.1e-41 139.3 0.0 9.8e-20 71.3 0.0 3.1 3 0 0 3 3 3 2 TIR domain Death PF00531.22 OWF40846.1 - 2.9e-11 43.4 2.5 1.7e-10 40.9 0.6 3.1 2 0 0 2 2 2 1 Death domain TIR PF01582.20 OWF40846.1 - 5.4e-07 29.6 0.0 0.0074 16.1 0.0 2.9 2 0 0 2 2 2 2 TIR domain Tropomyosin_1 PF12718.7 OWF40846.1 - 0.0092 16.1 4.1 0.033 14.3 4.1 1.9 1 0 0 1 1 1 1 Tropomyosin like PSDC PF12588.8 OWF40846.1 - 0.016 15.2 0.2 0.15 12.0 0.3 2.7 2 0 0 2 2 2 0 Phophatidylserine decarboxylase DUF1863 PF08937.11 OWF40846.1 - 0.028 14.7 0.0 2.1 8.7 0.0 3.3 3 1 0 3 3 2 0 MTH538 TIR-like domain (DUF1863) DUF16 PF01519.16 OWF40846.1 - 0.031 14.8 3.8 0.053 14.0 2.1 2.4 2 0 0 2 2 1 0 Protein of unknown function DUF16 Tropomyosin PF00261.20 OWF40846.1 - 0.06 12.7 4.9 0.18 11.2 4.9 1.8 1 0 0 1 1 1 0 Tropomyosin HrpB7 PF09486.10 OWF40846.1 - 0.098 13.0 0.5 0.21 11.9 0.5 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.6 OWF40846.1 - 0.22 10.2 6.2 0.31 9.6 2.4 2.2 2 0 0 2 2 2 0 AAA domain Noelin-1 PF12308.8 OWF40846.1 - 0.45 10.5 2.4 1.9 8.5 1.6 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein Fez1 PF06818.15 OWF40846.1 - 2.1 8.7 6.1 0.16 12.4 0.6 1.8 2 0 0 2 2 1 0 Fez1 Pyocin_S PF06958.12 OWF40846.1 - 3.1 8.4 7.6 3.4 8.2 0.2 2.4 2 0 0 2 2 2 0 S-type Pyocin FlaC_arch PF05377.11 OWF40846.1 - 4.1 7.9 5.4 13 6.3 2.9 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 OWF40846.1 - 4.4 7.3 10.4 0.86 9.6 5.2 2.5 2 1 1 3 3 3 0 Laminin Domain II ATG16 PF08614.11 OWF40846.1 - 8.3 6.6 15.2 0.9 9.7 0.1 2.7 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) TIR_2 PF13676.6 OWF40847.1 - 2.2e-42 144.4 0.0 1.4e-19 70.8 0.0 3.8 3 0 0 3 3 3 2 TIR domain Death PF00531.22 OWF40847.1 - 3.1e-11 43.3 0.7 1.7e-10 40.9 0.7 2.4 1 0 0 1 1 1 1 Death domain Adaptin_N PF01602.20 OWF40847.1 - 5.7e-05 21.9 1.9 0.0017 17.0 0.2 2.3 2 0 0 2 2 2 1 Adaptin N terminal region TIR PF01582.20 OWF40847.1 - 6.6e-05 22.8 12.0 0.0039 17.0 0.0 4.4 5 0 0 5 5 5 2 TIR domain Tropomyosin_1 PF12718.7 OWF40847.1 - 0.0039 17.3 2.6 0.0039 17.3 2.6 2.7 2 0 0 2 2 2 1 Tropomyosin like DUF1863 PF08937.11 OWF40847.1 - 0.047 14.0 0.0 1 9.7 0.0 3.0 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) DUF211 PF02680.14 OWF40847.1 - 0.15 12.2 6.8 0.43 10.8 6.8 1.8 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF2730 PF10805.8 OWF40847.1 - 0.39 10.8 3.6 1.6 8.8 3.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SPAM PF02090.15 OWF40847.1 - 1.3 8.9 6.1 0.13 12.1 0.8 2.0 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein HrpB7 PF09486.10 OWF40847.1 - 1.7 9.0 4.4 0.38 11.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.6 OWF40847.1 - 1.8 8.2 8.7 0.51 10.0 0.8 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.22 OWF40847.1 - 3.4 7.9 6.1 19 5.5 6.1 2.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 OWF40847.1 - 4.6 7.3 10.7 0.47 10.5 4.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OWF40847.1 - 6.3 6.8 10.8 0.17 11.9 2.8 2.5 3 0 0 3 3 2 0 Laminin Domain II DUF16 PF01519.16 OWF40847.1 - 7.3 7.1 15.7 0.22 12.0 4.5 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 XhlA PF10779.9 OWF40847.1 - 8.5 6.7 8.5 11 6.3 4.6 2.7 1 1 1 2 2 2 0 Haemolysin XhlA TIR_2 PF13676.6 OWF40848.1 - 1.9e-43 147.8 0.0 6.2e-20 72.0 0.0 3.6 3 0 0 3 3 2 2 TIR domain Death PF00531.22 OWF40848.1 - 1.6e-11 44.2 3.1 1.3e-10 41.3 0.7 3.3 3 0 0 3 3 2 1 Death domain WW PF00397.26 OWF40848.1 - 4.2e-08 33.1 0.8 9.9e-08 32.0 0.8 1.7 1 0 0 1 1 1 1 WW domain TIR PF01582.20 OWF40848.1 - 4.2e-07 29.9 0.0 0.011 15.6 0.0 3.3 2 0 0 2 2 2 2 TIR domain SPAM PF02090.15 OWF40848.1 - 0.003 17.4 0.6 0.0086 15.9 0.6 1.7 1 0 0 1 1 1 1 Salmonella surface presentation of antigen gene type M protein Tropomyosin_1 PF12718.7 OWF40848.1 - 0.025 14.8 4.3 0.065 13.4 4.3 1.7 1 0 0 1 1 1 0 Tropomyosin like Laminin_II PF06009.12 OWF40848.1 - 0.064 13.3 4.8 0.31 11.0 4.8 2.2 1 0 0 1 1 1 0 Laminin Domain II DUF1863 PF08937.11 OWF40848.1 - 0.071 13.4 0.0 3.5 8.0 0.0 3.1 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) DUF745 PF05335.13 OWF40848.1 - 0.11 12.3 0.4 0.31 10.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Spc7 PF08317.11 OWF40848.1 - 0.12 11.3 4.4 0.21 10.4 2.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 OWF40848.1 - 0.12 11.8 2.1 0.31 10.5 2.1 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein Herpes_UL79 PF03049.14 OWF40848.1 - 0.13 11.9 0.4 0.32 10.6 0.2 1.7 2 0 0 2 2 1 0 UL79 family DUF2730 PF10805.8 OWF40848.1 - 0.16 12.1 4.0 0.84 9.8 4.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Syntaxin PF00804.25 OWF40848.1 - 0.25 11.0 7.4 0.31 10.7 5.4 2.3 2 0 0 2 2 2 0 Syntaxin DUF211 PF02680.14 OWF40848.1 - 0.65 10.2 7.2 1.7 8.9 7.2 1.7 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF16 PF01519.16 OWF40848.1 - 0.97 10.0 8.6 0.29 11.6 4.1 2.6 2 0 0 2 2 1 0 Protein of unknown function DUF16 KxDL PF10241.9 OWF40848.1 - 1.4 9.2 5.0 2.8 8.3 2.4 2.9 2 1 0 2 2 1 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 OWF40848.1 - 1.5 8.8 7.6 0.18 11.8 2.8 1.9 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Noelin-1 PF12308.8 OWF40848.1 - 1.6 8.7 3.9 6.7 6.8 3.9 2.1 1 0 0 1 1 1 0 Neurogenesis glycoprotein Seryl_tRNA_N PF02403.22 OWF40848.1 - 1.7 8.9 5.9 10 6.4 5.9 2.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4795 PF16043.5 OWF40848.1 - 2 8.0 7.2 6.8 6.2 1.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) BLOC1_2 PF10046.9 OWF40848.1 - 4.1 7.8 7.5 2.2 8.7 3.5 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.6 OWF40848.1 - 7.7 6.2 13.1 0.13 12.0 5.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 OWF40848.1 - 7.8 7.0 10.0 1.3e+02 3.1 10.0 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 OWF40848.1 - 9 6.8 8.2 4.3e+02 1.4 8.2 3.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) PTS_2-RNA PF01885.16 OWF40849.1 - 6.8e-22 78.4 0.0 8e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family TIR_2 PF13676.6 OWF40850.1 - 2e-44 151.0 0.0 5.9e-21 75.3 0.0 2.9 3 0 0 3 3 3 2 TIR domain Death PF00531.22 OWF40850.1 - 3.3e-12 46.4 1.7 4.2e-12 46.1 0.6 1.8 2 0 0 2 2 2 1 Death domain TIR PF01582.20 OWF40850.1 - 2.6e-09 37.1 0.1 0.00043 20.1 0.0 2.9 3 0 0 3 3 3 2 TIR domain DUF16 PF01519.16 OWF40850.1 - 0.00064 20.2 2.2 0.0025 18.3 1.6 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 Tropomyosin_1 PF12718.7 OWF40850.1 - 0.005 17.0 0.5 0.0089 16.2 0.5 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF1863 PF08937.11 OWF40850.1 - 0.019 15.3 0.0 0.84 10.0 0.0 2.9 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) Fez1 PF06818.15 OWF40850.1 - 0.054 14.0 0.5 0.092 13.2 0.5 1.4 1 0 0 1 1 1 0 Fez1 E2R135 PF11570.8 OWF40850.1 - 0.09 13.1 0.4 0.22 11.8 0.4 1.6 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 MIF4G_like_2 PF09090.11 OWF40850.1 - 0.13 11.7 0.2 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 MIF4G like Laminin_II PF06009.12 OWF40850.1 - 0.15 12.0 3.4 0.063 13.3 0.8 1.7 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 OWF40850.1 - 6.7 7.3 7.0 21 5.6 4.5 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 OWF40850.1 - 8.6 6.7 6.2 5 7.4 1.1 2.3 1 1 1 2 2 2 0 Haemolysin XhlA FolB PF02152.18 OWF40851.1 - 0.0037 17.8 4.5 63 4.2 4.5 4.2 1 1 0 1 1 1 0 Dihydroneopterin aldolase DUF1163 PF06651.11 OWF40851.1 - 0.0071 16.4 2.7 7.3 6.8 0.3 4.2 1 1 4 5 5 5 1 Protein of unknown function (DUF1163) Propep_M14 PF02244.16 OWF40851.1 - 0.0076 16.6 0.5 38 4.8 0.0 3.8 1 1 3 5 5 5 0 Carboxypeptidase activation peptide NEMO PF11577.8 OWF40851.1 - 0.011 15.8 5.0 3.8 7.6 0.4 4.0 1 1 3 4 4 4 0 NF-kappa-B essential modulator NEMO DUF4809 PF16067.5 OWF40851.1 - 0.012 15.8 6.4 3.1 8.0 0.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4809) DUF836 PF05768.14 OWF40851.1 - 0.012 16.0 3.4 12 6.4 3.4 3.1 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF1137 PF06587.11 OWF40851.1 - 0.037 14.0 0.7 14 5.7 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1137) Tcp10_C PF07202.13 OWF40851.1 - 0.05 13.6 3.7 0.93 9.4 0.4 2.0 1 1 1 2 2 2 0 T-complex protein 10 C-terminus Ets PF00178.22 OWF40851.1 - 0.13 12.7 19.5 24 5.5 0.4 5.1 1 1 1 2 2 2 0 Ets-domain DUF3106 PF11304.8 OWF40851.1 - 0.14 12.6 3.7 0.44 11.0 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Ribosomal_S17 PF00366.20 OWF40851.1 - 0.21 11.7 1.9 11 6.2 0.1 3.3 1 1 2 3 3 3 0 Ribosomal protein S17 DMAP1_like PF17024.5 OWF40851.1 - 0.56 10.3 13.9 5.5 7.2 1.7 3.3 1 1 3 4 4 4 0 Putative DMAP1-like AAA_5 PF07728.14 OWF40851.1 - 1.5 8.8 6.5 94 3.0 6.4 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FolB PF02152.18 OWF40852.1 - 0.021 15.4 3.5 7.2 7.2 1.4 3.1 1 1 1 2 2 2 0 Dihydroneopterin aldolase Cas_Cmr5 PF09701.10 OWF40852.1 - 0.091 13.1 2.1 5.6 7.3 2.1 2.2 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Ets PF00178.22 OWF40852.1 - 0.092 13.2 2.9 14 6.3 0.6 2.9 1 1 1 2 2 2 0 Ets-domain Baculo_PEP_C PF04513.12 OWF40853.1 - 8.6e-20 71.2 3.1 0.0039 17.2 0.0 6.0 1 1 4 5 5 5 5 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 OWF40853.1 - 1.4e-15 57.6 0.0 0.0015 18.7 0.0 5.8 1 1 3 6 6 6 5 Apolipophorin-III precursor (apoLp-III) DegQ PF08181.11 OWF40853.1 - 4e-15 55.6 7.4 14 5.8 0.0 14.0 2 2 13 17 17 17 0 DegQ (SacQ) family SF-assemblin PF06705.11 OWF40853.1 - 9.7e-13 48.0 1.9 0.3 10.4 0.1 6.2 1 1 6 7 7 7 7 SF-assemblin/beta giardin DUF1664 PF07889.12 OWF40853.1 - 7e-11 42.2 12.9 0.27 11.3 0.1 7.5 1 1 5 6 6 6 4 Protein of unknown function (DUF1664) CheZ PF04344.13 OWF40853.1 - 2.4e-08 34.2 21.7 0.55 10.1 0.9 8.2 1 1 3 6 6 6 3 Chemotaxis phosphatase, CheZ Focal_AT PF03623.13 OWF40853.1 - 2.9e-08 33.8 37.0 1.1 9.3 0.4 8.0 1 1 6 7 7 7 6 Focal adhesion targeting region Serine_rich PF08824.10 OWF40853.1 - 2e-07 31.2 30.7 0.37 10.8 0.9 6.6 1 1 7 8 8 8 7 Serine rich protein interaction domain Prominin PF05478.11 OWF40853.1 - 3.8e-07 28.5 45.7 0.004 15.2 24.3 4.3 1 1 3 4 4 4 4 Prominin TGS PF02824.21 OWF40853.1 - 2.7e-05 24.1 9.2 46 4.2 0.0 11.0 5 4 7 13 13 13 0 TGS domain T3SS_needle_F PF09392.10 OWF40853.1 - 8.4e-05 22.7 2.1 1.8e+02 2.4 0.0 8.3 3 3 6 11 11 11 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Exonuc_VII_L PF02601.15 OWF40853.1 - 0.00013 21.6 34.6 0.21 11.1 5.3 4.4 1 1 1 2 2 1 1 Exonuclease VII, large subunit IZUMO PF15005.6 OWF40853.1 - 0.00088 19.8 24.4 1.3 9.5 1.6 5.7 1 1 4 5 5 5 3 Izumo sperm-egg fusion, Ig domain-associated Gp-FAR-1 PF05823.12 OWF40853.1 - 0.0009 19.6 12.6 0.84 10.0 0.2 5.7 1 1 6 7 7 7 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DLP_helical PF18709.1 OWF40853.1 - 0.00091 18.5 9.4 4.3 6.4 0.3 5.2 1 1 4 5 5 5 2 Dynamin-like helical domain Apolipoprotein PF01442.18 OWF40853.1 - 0.0047 16.8 0.0 1.2 9.0 0.0 3.2 1 1 2 3 3 3 1 Apolipoprotein A1/A4/E domain Peptidase_S41_N PF11918.8 OWF40853.1 - 0.75 10.0 63.8 1.6 8.9 3.5 8.1 1 1 7 8 8 8 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP TSP_1 PF00090.19 OWF40856.1 - 1.5e-56 188.4 102.7 1.2e-11 44.6 5.2 9.0 8 0 0 8 8 8 8 Thrombospondin type 1 domain Laminin_G_2 PF02210.24 OWF40856.1 - 2.9e-15 57.0 0.3 9.1e-07 29.5 0.1 2.6 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 OWF40856.1 - 6.9e-11 42.5 0.2 0.0003 21.0 0.1 2.6 2 0 0 2 2 2 2 Laminin G domain DUF1652 PF07865.11 OWF40856.1 - 0.16 11.8 0.1 11 5.9 0.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1652) MIP PF00230.20 OWF40857.1 - 2.1e-49 168.3 16.1 3.5e-49 167.6 16.1 1.3 1 1 0 1 1 1 1 Major intrinsic protein PRKCSH_1 PF13015.6 OWF40858.1 - 5.8e-12 45.6 0.1 1.2e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OWF40858.1 - 3.5e-05 24.7 1.4 3.5e-05 24.7 1.4 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF4763 PF15960.5 OWF40858.1 - 0.011 15.0 0.4 0.017 14.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DMAP_binding PF06464.11 OWF40858.1 - 0.046 14.5 1.6 0.08 13.8 1.6 1.3 1 0 0 1 1 1 0 DMAP1-binding Domain Seryl_tRNA_N PF02403.22 OWF40858.1 - 0.24 11.7 2.1 0.41 10.9 2.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3677 PF12432.8 OWF40859.1 - 1.3e-30 105.5 3.5 1.3e-30 105.5 3.5 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3677) Cnd1 PF12717.7 OWF40859.1 - 0.2 11.7 5.1 0.18 11.9 0.1 3.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 p450 PF00067.22 OWF40860.1 - 6.9e-101 338.3 0.1 7.9e-101 338.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Calsarcin PF05556.11 OWF40861.1 - 2.7e-14 53.3 3.5 1.2e-06 28.3 0.5 3.5 2 1 1 3 3 3 3 Calcineurin-binding protein (Calsarcin) PDZ PF00595.24 OWF40861.1 - 1.3e-07 31.9 0.0 2.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF40861.1 - 4.5e-06 26.4 0.0 8.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF40861.1 - 0.0026 18.0 0.0 0.0061 16.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain TMEM154 PF15102.6 OWF40862.1 - 0.11 12.4 0.7 1 9.3 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family TMEM154 PF15102.6 OWF40863.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 2.0 2 1 1 3 3 3 1 TMEM154 protein family Gag_p6 PF08705.11 OWF40863.1 - 0.035 14.4 0.2 0.14 12.5 0.2 2.1 1 0 0 1 1 1 0 Gag protein p6 Phage_holin_2_1 PF04971.12 OWF40863.1 - 0.036 14.1 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S TMEM51 PF15345.6 OWF40863.1 - 0.054 13.3 0.1 0.054 13.3 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2207 PF09972.9 OWF40863.1 - 0.075 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OWF40863.1 - 0.079 13.3 0.4 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF1180 PF06679.12 OWF40863.1 - 0.088 13.2 5.9 0.2 12.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DUF3377 PF11857.8 OWF40863.1 - 0.21 11.5 2.8 0.75 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) MFS_1 PF07690.16 OWF40864.1 - 0.0082 15.1 0.1 0.013 14.4 0.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3242 PF11586.8 OWF40865.1 - 4.1e-05 23.3 0.0 1.8 8.3 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3242) HTH_Tnp_ISL3 PF13542.6 OWF40865.1 - 0.00017 21.0 38.9 6.6 6.2 0.1 10.7 11 0 0 11 11 11 5 Helix-turn-helix domain of transposase family ISL3 Extensin-like_C PF06904.12 OWF40865.1 - 0.0024 17.9 11.2 37 4.3 0.1 6.0 1 1 4 6 6 6 0 Extensin-like protein C-terminus Adeno_E3B PF03376.14 OWF40865.1 - 0.012 15.8 11.1 21 5.4 0.1 6.8 3 2 5 8 8 8 0 Adenovirus E3B protein PIG-H PF10181.9 OWF40865.1 - 0.039 13.8 8.1 1.8e+02 2.0 0.0 6.9 8 0 0 8 8 8 0 GPI-GlcNAc transferase complex, PIG-H component Condensin2nSMC PF12422.8 OWF40865.1 - 0.085 13.0 0.1 9 6.5 0.0 2.8 1 1 4 5 5 5 0 Condensin II non structural maintenance of chromosomes subunit RhoGAP-FF1 PF16512.5 OWF40865.1 - 0.24 12.1 13.7 1.8e+02 2.9 0.0 7.1 7 1 1 8 8 8 0 p190-A and -B Rho GAPs FF domain DUF2784 PF10861.8 OWF40865.1 - 9.2 6.3 24.2 2.8 8.0 0.5 6.5 1 1 7 8 8 8 0 Protein of Unknown function (DUF2784) VWC PF00093.18 OWF40866.1 - 4.5e-07 30.1 13.7 4.5e-07 30.1 13.7 3.1 3 1 0 3 3 3 1 von Willebrand factor type C domain TILa PF12714.7 OWF40866.1 - 0.0015 18.5 12.4 0.0015 18.5 12.4 2.2 2 1 0 2 2 2 1 TILa domain VWC PF00093.18 OWF40867.1 - 1.4e-21 76.5 67.7 1.2e-08 35.2 13.4 4.3 5 0 0 5 5 5 3 von Willebrand factor type C domain TILa PF12714.7 OWF40867.1 - 0.0033 17.4 12.4 0.0033 17.4 12.4 5.0 4 2 1 5 5 5 3 TILa domain Chlam_OMP3 PF03503.13 OWF40868.1 - 2.4 8.5 13.2 4.2 7.7 1.3 3.0 2 1 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 Esterase PF00756.20 OWF40869.1 - 1.1e-62 212.0 0.0 1.3e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OWF40869.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OWF40869.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OWF40869.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OWF40869.1 - 0.026 13.5 0.0 0.081 11.9 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase DLH PF01738.18 OWF40869.1 - 0.063 12.8 0.4 0.14 11.6 0.4 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Dynein_C PF18199.1 OWF40869.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain Esterase_phd PF10503.9 OWF40869.1 - 0.17 11.3 0.0 0.7 9.3 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase Ldl_recept_b PF00058.17 OWF40871.1 - 2.2e-68 226.5 32.6 1.3e-12 47.9 0.0 13.0 14 0 0 14 14 14 10 Low-density lipoprotein receptor repeat class B SGL PF08450.12 OWF40871.1 - 1.2e-13 51.2 11.0 0.13 11.8 0.0 7.2 4 3 3 7 7 7 5 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 OWF40871.1 - 1.5e-11 44.4 37.0 0.00012 22.2 7.5 3.5 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF40871.1 - 0.00033 20.5 19.1 0.16 11.9 1.1 3.9 3 0 0 3 3 3 3 Complement Clr-like EGF-like SBBP PF06739.11 OWF40871.1 - 0.19 11.7 1.7 4 7.5 0.0 3.6 4 0 0 4 4 4 0 Beta-propeller repeat PGF-CTERM PF18204.1 OWF40871.1 - 8.9 6.4 6.6 0.28 11.2 0.5 1.7 2 0 0 2 2 2 0 PGF-CTERM motif SH3_10 PF17902.1 OWF40872.1 - 5e-17 61.7 0.4 1.1e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 SH3 domain Plectin PF00681.20 OWF40872.1 - 4.7e-09 36.0 0.0 0.71 9.8 0.0 5.2 5 1 1 6 6 6 3 Plectin repeat SH3_1 PF00018.28 OWF40872.1 - 0.02 14.5 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Spectrin PF00435.21 OWF40872.1 - 0.11 13.0 1.6 9.1 6.8 0.1 3.5 3 0 0 3 3 3 0 Spectrin repeat Dishevelled PF02377.15 OWF40872.1 - 0.53 10.7 6.2 8.2 6.9 0.5 2.4 2 0 0 2 2 2 0 Dishevelled specific domain MgtE_N PF03448.17 OWF40873.1 - 0.00072 20.1 0.0 1.2 9.8 0.0 2.4 1 1 1 2 2 2 2 MgtE intracellular N domain DUF2964 PF11177.8 OWF40873.1 - 0.00087 19.4 6.2 50 4.2 0.2 7.0 1 1 3 6 6 6 0 Protein of unknown function (DUF2964) TraD PF06412.11 OWF40873.1 - 0.023 14.5 0.4 22 4.9 0.0 4.1 3 2 0 4 4 4 0 Conjugal transfer protein TraD DUF4270 PF14092.6 OWF40873.1 - 0.059 12.5 1.1 67 2.4 0.0 4.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4270) Rogdi_lz PF10259.9 OWF40873.1 - 0.076 12.5 3.3 35 3.7 0.3 4.0 2 1 0 3 3 3 0 Rogdi leucine zipper containing protein FAM194 PF14977.6 OWF40873.1 - 0.1 11.9 3.5 22 4.3 0.1 4.3 1 1 3 6 6 6 0 FAM194 protein MreD PF04093.12 OWF40873.1 - 0.29 11.2 9.0 27 4.8 0.2 6.0 6 4 2 8 8 8 0 rod shape-determining protein MreD Phage_holin_3_3 PF16083.5 OWF40873.1 - 4.7 7.4 14.0 35 4.6 0.2 5.9 3 3 4 7 7 7 0 LydA holin phage, holin superfamily III F1F0-ATPsyn_F PF10791.9 OWF40874.1 - 0.021 15.3 0.8 3.8 8.1 0.1 3.7 3 1 1 4 4 4 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Olduvai PF06758.13 OWF40874.1 - 0.054 13.8 0.6 0.89 9.9 0.0 2.4 2 0 0 2 2 2 0 Olduvai domain Med12-LCEWAV PF12145.8 OWF40875.1 - 2.8e-154 514.5 0.1 5.8e-154 513.5 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 OWF40875.1 - 2.3e-11 43.8 0.1 5.8e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Arc PF03869.14 OWF40877.1 - 0.039 13.8 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Arc-like DNA binding domain Methyltransf_21 PF05050.12 OWF40878.1 - 4.5e-05 23.5 0.1 0.00058 19.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase FkbM domain Galactosyl_T PF01762.21 OWF40879.1 - 6.2e-27 94.7 0.2 9e-27 94.2 0.2 1.1 1 0 0 1 1 1 1 Galactosyltransferase Methyltransf_21 PF05050.12 OWF40880.1 - 2.2e-06 27.8 0.1 8.4e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase FkbM domain CxC5 PF18718.1 OWF40880.1 - 4.2 7.5 10.1 4.4 7.4 0.2 3.5 3 0 0 3 3 3 0 CxC5 like cysteine cluster associated with KDZ transposases Serpin PF00079.20 OWF40881.1 - 3.1e-121 405.2 3.6 3.6e-121 405.0 3.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1460 PF07313.12 OWF40881.1 - 0.1 11.9 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) DUF4744 PF15918.5 OWF40882.1 - 0.011 16.5 0.0 0.4 11.6 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) tRNA-synt_2c PF01411.19 OWF40882.1 - 0.37 9.2 1.1 9.1 4.7 0.1 2.3 1 1 2 3 3 3 0 tRNA synthetases class II (A) TFIIA_gamma_C PF02751.14 OWF40883.1 - 0.0053 16.9 0.1 5.9 7.1 0.1 3.2 1 1 1 2 2 2 2 Transcription initiation factor IIA, gamma subunit DUF4744 PF15918.5 OWF40883.1 - 0.017 16.0 0.0 0.75 10.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) Serpin PF00079.20 OWF40884.1 - 1.5e-123 412.8 4.4 1.7e-123 412.6 4.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1104 PF06518.11 OWF40884.1 - 0.016 15.6 1.3 5.4 7.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) DUF273 PF03314.14 OWF40884.1 - 0.043 13.4 0.8 0.078 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF273 DUF1460 PF07313.12 OWF40884.1 - 0.087 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) UCH PF00443.29 OWF40886.1 - 3.8e-49 167.5 0.4 3.8e-49 167.5 0.4 2.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF40886.1 - 1.6e-28 100.2 0.2 1.7e-27 96.9 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CPSase_L_D2 PF02786.17 OWF40887.1 - 3.1e-80 268.6 0.0 4.7e-80 268.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OWF40887.1 - 2e-42 144.2 0.0 4.9e-42 143.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OWF40887.1 - 2.4e-33 114.5 0.0 6e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 OWF40887.1 - 6.9e-24 84.6 0.0 2.6e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 OWF40887.1 - 7e-17 61.0 4.8 1e-16 60.5 3.8 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OWF40887.1 - 5.9e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OWF40887.1 - 2.7e-08 33.6 0.0 5.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OWF40887.1 - 2.5e-07 30.4 2.7 0.001 18.9 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like RimK PF08443.11 OWF40887.1 - 6.4e-06 25.9 0.0 2.5e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 OWF40887.1 - 7.3e-06 26.1 0.0 2.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 OWF40887.1 - 0.0025 18.5 0.5 0.26 12.0 0.1 3.0 3 0 0 3 3 3 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 OWF40887.1 - 0.0069 15.7 0.0 0.045 13.0 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 OWF40887.1 - 0.008 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 OWF40887.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon AP_endonuc_2 PF01261.24 OWF40887.1 - 0.08 12.4 0.0 5.5 6.4 0.0 2.4 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Glyoxalase_4 PF13669.6 OWF40887.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ATP-grasp_5 PF13549.6 OWF40887.1 - 0.12 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RhoGAP PF00620.27 OWF40888.1 - 5e-37 127.1 0.0 1.1e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 OWF40888.1 - 1.1e-07 31.7 4.1 1.1e-07 31.7 4.1 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HMMR_N PF15905.5 OWF40888.1 - 0.0055 16.2 5.4 0.0098 15.4 5.4 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Cep57_CLD_2 PF14197.6 OWF40888.1 - 0.0059 16.7 8.0 0.012 15.7 7.6 1.8 1 1 0 1 1 1 1 Centrosome localisation domain of PPC89 TRAF_BIRC3_bd PF16673.5 OWF40888.1 - 0.058 13.2 2.1 0.12 12.2 2.1 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain TrwB_AAD_bind PF10412.9 OWF40888.1 - 0.14 11.1 1.1 0.2 10.5 1.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CorA PF01544.18 OWF40888.1 - 1.7 7.9 7.4 2.8 7.2 7.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 OWF40888.1 - 3.2 7.2 6.7 4.9 6.6 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 OWF40888.1 - 4.3 8.0 6.5 11 6.7 6.4 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Spindle_Spc25 PF08234.12 OWF40889.1 - 2.8e-18 65.9 0.7 2.8e-18 65.9 0.7 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 FTR1 PF03239.14 OWF40889.1 - 0.32 10.1 1.3 0.54 9.4 1.3 1.4 1 0 0 1 1 1 0 Iron permease FTR1 family DASH_Dam1 PF08653.10 OWF40889.1 - 0.72 9.7 2.6 1.1 9.2 0.5 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 Synaptobrevin PF00957.21 OWF40889.1 - 1.1 9.1 8.1 0.19 11.6 3.6 2.1 2 1 0 2 2 2 0 Synaptobrevin TPR_MLP1_2 PF07926.12 OWF40889.1 - 5.2 7.2 35.5 0.092 12.8 21.3 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Ras PF00071.22 OWF40890.1 - 6e-59 198.3 0.3 7e-59 198.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF40890.1 - 2e-37 128.1 0.1 3.1e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF40890.1 - 7.8e-19 67.8 0.2 9.9e-19 67.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF40890.1 - 8.6e-08 32.3 0.1 2.6e-07 30.7 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF40890.1 - 1.1e-06 28.2 0.1 1.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF40890.1 - 3.7e-06 26.6 0.3 3.2e-05 23.6 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF40890.1 - 2.8e-05 24.1 0.1 0.013 15.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OWF40890.1 - 0.00022 21.0 0.1 0.00045 20.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 OWF40890.1 - 0.00048 19.6 0.1 0.00075 19.0 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OWF40890.1 - 0.0023 17.7 0.2 0.017 14.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OWF40890.1 - 0.0025 18.2 0.1 0.0042 17.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF40890.1 - 0.0027 18.0 0.0 0.007 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OWF40890.1 - 0.0054 17.3 0.2 0.014 15.9 0.2 1.9 1 1 0 1 1 1 1 ABC transporter CENP-M PF11111.8 OWF40890.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_29 PF13555.6 OWF40890.1 - 0.012 15.4 0.7 0.026 14.2 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OWF40890.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 OWF40890.1 - 0.041 13.2 0.2 0.086 12.1 0.0 1.5 2 0 0 2 2 2 0 Septin TniB PF05621.11 OWF40890.1 - 0.055 12.9 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 OWF40890.1 - 0.076 12.1 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain PhyH PF05721.13 OWF40890.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Hpr_kinase_C PF07475.12 OWF40890.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Cytochrom_C PF00034.21 OWF40891.1 - 3.2e-24 85.9 0.0 5.4e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 OWF40891.1 - 3.5e-13 49.7 3.4 2e-05 24.8 0.5 3.5 3 2 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OWF40891.1 - 2.5e-05 24.0 4.6 0.028 14.1 0.2 2.8 2 1 1 3 3 3 2 Cytochrome c-550 domain CCP_MauG PF03150.14 OWF40891.1 - 0.01 16.5 0.0 0.99 10.0 0.0 2.2 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase DUF2024 PF09630.10 OWF40891.1 - 0.056 13.3 0.5 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Cytochrome-c551 PF10643.9 OWF40891.1 - 0.07 12.7 0.1 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.6 OWF40891.1 - 0.12 12.4 0.0 21 5.1 0.0 2.3 2 0 0 2 2 2 0 Haem-binding domain Dehyd-heme_bind PF09098.10 OWF40891.1 - 0.22 11.1 0.3 17 5.0 0.1 2.3 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Cytochrome_P460 PF16694.5 OWF40891.1 - 4.2 7.7 6.1 41 4.5 0.2 3.2 3 1 1 4 4 4 0 Cytochrome P460 Prefoldin_2 PF01920.20 OWF40892.1 - 0.0015 18.4 3.6 0.0019 18.1 3.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit RIIa PF02197.17 OWF40893.1 - 3.5e-05 23.4 1.1 7.1e-05 22.4 1.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Peptidase_C14 PF00656.22 OWF40893.1 - 0.056 13.4 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 Caspase domain DNA_mis_repair PF01119.19 OWF40894.1 - 2.5e-20 72.3 0.2 3.6e-19 68.6 0.1 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OWF40894.1 - 6.7e-12 45.4 0.1 1.7e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OWF40894.1 - 5e-06 27.0 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box PF00505.19 OWF40894.1 - 3e-05 24.4 0.0 6.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF40894.1 - 0.002 18.7 0.0 0.0041 17.7 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Dynamitin PF04912.14 OWF40895.1 - 1.4e-118 396.6 17.5 1.6e-118 396.5 17.5 1.0 1 0 0 1 1 1 1 Dynamitin Seryl_tRNA_N PF02403.22 OWF40895.1 - 0.0077 16.4 16.8 2.3 8.5 1.1 4.6 2 2 3 5 5 5 1 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 OWF40895.1 - 0.011 16.2 19.3 0.16 12.4 0.2 5.1 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 OWF40895.1 - 0.011 15.5 1.5 0.8 9.5 0.1 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tropomyosin_1 PF12718.7 OWF40895.1 - 0.015 15.4 4.7 0.015 15.4 4.7 3.6 2 1 1 3 3 3 0 Tropomyosin like Allexi_40kDa PF05549.11 OWF40895.1 - 0.023 14.2 10.9 0.17 11.3 0.1 3.2 2 1 1 3 3 3 0 Allexivirus 40kDa protein CorA PF01544.18 OWF40895.1 - 0.048 13.0 13.7 0.31 10.3 0.8 3.1 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein DELLA PF12041.8 OWF40895.1 - 0.059 13.3 0.2 0.19 11.6 0.2 1.9 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DUF1664 PF07889.12 OWF40895.1 - 0.09 12.8 13.2 0.71 9.9 0.8 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OWF40895.1 - 0.12 12.5 23.6 0.23 11.5 2.2 3.9 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 OWF40895.1 - 0.12 12.6 21.0 0.35 11.2 0.6 4.5 3 1 1 4 4 4 0 ABC transporter C-terminal domain Laminin_II PF06009.12 OWF40895.1 - 0.14 12.2 15.7 0.33 11.0 3.0 3.5 2 1 2 4 4 4 0 Laminin Domain II BLOC1_2 PF10046.9 OWF40895.1 - 0.15 12.4 14.1 0.52 10.7 0.1 4.4 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 OWF40895.1 - 0.16 12.5 22.1 1.2 9.7 2.7 4.2 2 1 3 5 5 5 0 Spectrin repeat DUF573 PF04504.14 OWF40895.1 - 0.31 11.7 4.1 0.45 11.2 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DUF1465 PF07323.12 OWF40895.1 - 0.57 10.0 6.6 0.66 9.8 0.3 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1465) DUF4140 PF13600.6 OWF40895.1 - 0.67 10.4 12.3 4.8 7.7 0.4 4.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Occludin_ELL PF07303.13 OWF40895.1 - 0.7 10.6 16.2 0.55 11.0 2.0 4.0 2 1 2 4 4 4 0 Occludin homology domain FlaC_arch PF05377.11 OWF40895.1 - 0.76 10.2 15.2 0.17 12.3 0.9 4.7 4 2 0 4 4 4 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 OWF40895.1 - 1.3 9.3 11.8 20 5.5 0.1 4.9 5 0 0 5 5 5 0 Haemolysin XhlA FapA PF03961.13 OWF40895.1 - 1.9 7.0 13.3 10 4.6 0.5 2.9 2 1 0 2 2 2 0 Flagellar Assembly Protein A FUSC PF04632.12 OWF40895.1 - 2.8 6.4 7.0 8.8 4.7 2.1 2.6 2 1 0 2 2 2 0 Fusaric acid resistance protein family FAP206 PF12018.8 OWF40895.1 - 3 7.3 11.4 0.27 10.7 1.0 3.0 2 1 0 3 3 3 0 Domain of unknown function Jnk-SapK_ap_N PF09744.9 OWF40895.1 - 3.6 7.8 19.1 7.4 6.8 0.8 3.4 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 DASH_Dam1 PF08653.10 OWF40895.1 - 4.5 7.2 6.5 27 4.7 0.1 4.0 4 1 1 5 5 5 0 DASH complex subunit Dam1 Atg14 PF10186.9 OWF40895.1 - 4.5 6.3 15.4 8.7 5.3 7.0 2.8 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 PMC2NT PF08066.12 OWF40895.1 - 5 7.9 6.3 3 8.6 0.5 3.0 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Cauli_AT PF03233.13 OWF40895.1 - 5.3 6.9 7.3 2.5 8.0 0.5 2.8 2 1 0 2 2 2 0 Aphid transmission protein SesA PF17107.5 OWF40895.1 - 6.3 7.0 10.0 2.2 8.5 0.6 3.4 2 1 2 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TMPIT PF07851.13 OWF40895.1 - 6.9 5.8 13.0 1.5 8.0 0.3 3.3 2 1 2 4 4 4 0 TMPIT-like protein Fib_alpha PF08702.10 OWF40895.1 - 9.6 6.4 15.8 13 6.0 4.6 3.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 OWF40896.1 - 6.2e-38 130.7 0.0 7.8e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF40896.1 - 1.6e-20 73.5 0.0 2e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF40896.1 - 0.0018 17.7 0.0 0.004 16.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OWF40896.1 - 0.095 12.6 0.1 0.61 10.0 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF5334 PF17268.2 OWF40897.1 - 9.7e-05 22.6 29.7 3.4 8.1 0.5 9.1 2 2 8 11 11 11 4 Family of unknown function (DUF5334) Av_adeno_fibre PF06536.11 OWF40897.1 - 0.0003 20.6 0.8 11 6.0 0.0 7.3 5 4 4 9 9 9 1 Avian adenovirus fibre, N-terminal DUF2993 PF11209.8 OWF40897.1 - 0.0021 18.3 21.7 1.1 9.5 0.1 5.6 1 1 4 5 5 5 2 Protein of unknown function (DUF2993) YabP PF07873.11 OWF40897.1 - 0.0076 16.0 12.2 14 5.6 0.1 6.4 6 0 0 6 6 6 1 YabP family 4HBT_2 PF13279.6 OWF40897.1 - 0.015 15.8 18.3 38 4.8 2.0 6.0 1 1 1 2 2 2 0 Thioesterase-like superfamily DUF3557 PF12078.8 OWF40897.1 - 0.086 12.8 20.6 9.7 6.1 1.9 6.1 1 1 3 4 4 4 0 Domain of unknown function (DUF3557) MMTV_SAg PF01054.17 OWF40897.1 - 0.15 11.6 1.2 54 3.2 0.0 4.6 1 1 4 5 5 5 0 Mouse mammary tumour virus superantigen GCN5L1 PF06320.13 OWF40898.1 - 0.00016 21.8 9.8 1.9 8.7 0.0 5.4 3 2 2 6 6 6 2 GCN5-like protein 1 (GCN5L1) Av_adeno_fibre PF06536.11 OWF40898.1 - 0.0099 15.7 4.3 41 4.1 0.1 5.7 3 1 1 4 4 4 0 Avian adenovirus fibre, N-terminal DUF1664 PF07889.12 OWF40898.1 - 0.036 14.1 16.8 3.7 7.6 1.3 5.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF5334 PF17268.2 OWF40898.1 - 0.056 13.8 34.4 11 6.4 0.9 7.4 1 1 5 6 6 6 0 Family of unknown function (DUF5334) TMF_TATA_bd PF12325.8 OWF40898.1 - 0.34 11.1 2.9 2.5 8.4 0.2 3.2 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3557 PF12078.8 OWF40898.1 - 0.36 10.8 20.3 1.7 8.6 1.5 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF3557) DUF2730 PF10805.8 OWF40898.1 - 0.93 9.6 11.2 6.7 6.9 0.6 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) CheZ PF04344.13 OWF40898.1 - 2.5 8.0 10.4 0.31 10.9 4.0 2.5 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF5126 PF17166.4 OWF40898.1 - 4.5 7.2 9.3 11 6.0 1.6 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF5126) Jnk-SapK_ap_N PF09744.9 OWF40898.1 - 6.3 7.0 6.4 3.6 7.8 0.3 3.2 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF4744 PF15918.5 OWF40898.1 - 6.4 7.7 13.0 15 6.5 13.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) Talin_middle PF09141.10 OWF40898.1 - 9.3 6.3 8.0 26 4.8 0.4 3.7 2 1 1 3 3 3 0 Talin, middle domain Baculo_PEP_C PF04513.12 OWF40900.1 - 0.0079 16.2 9.3 0.066 13.3 1.2 4.5 3 1 2 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 OWF40900.1 - 0.29 11.4 9.6 8.3 6.7 0.0 5.5 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 OWF40900.1 - 1.1 9.8 4.5 3.8 8.1 0.1 4.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_G_3 PF13385.6 OWF40901.1 - 1.2e-07 32.0 1.0 1.9e-07 31.4 1.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OWF40901.1 - 0.049 14.2 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain DUF1508 PF07411.12 OWF40901.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Acyl-CoA_dh_1 PF00441.24 OWF40902.1 - 5.6e-42 143.5 3.6 2.5e-38 131.6 1.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OWF40902.1 - 5.3e-23 81.0 0.1 1.2e-22 79.9 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OWF40902.1 - 8e-23 81.3 0.0 2.7e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OWF40902.1 - 1.3e-12 48.1 1.0 6e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Mor PF08765.11 OWF40902.1 - 0.12 12.4 0.2 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Mor transcription activator family Med11 PF10280.9 OWF40903.1 - 1.8e-17 64.1 4.0 2.1e-17 63.8 4.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF848 PF05852.11 OWF40903.1 - 0.028 14.5 0.3 0.04 14.0 0.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Collagen_mid PF15984.5 OWF40903.1 - 0.029 14.1 0.3 0.037 13.8 0.3 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region DUF5446 PF17522.2 OWF40903.1 - 0.053 13.7 2.1 8.3 6.7 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5446) DUF4806 PF16064.5 OWF40903.1 - 0.056 13.7 0.2 0.1 12.9 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) DUF4164 PF13747.6 OWF40903.1 - 0.087 13.1 0.7 2.2 8.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) RasGAP_C PF03836.15 OWF40903.1 - 0.13 12.4 3.3 0.17 12.0 3.3 1.3 1 1 0 1 1 1 0 RasGAP C-terminus Baculo_PEP_C PF04513.12 OWF40903.1 - 0.6 10.2 4.2 0.68 10.0 3.3 1.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHR10 PF18595.1 OWF40903.1 - 2 8.5 10.2 2 8.5 3.5 2.7 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain SAM_1 PF00536.30 OWF40904.1 - 4.5e-14 52.6 0.0 1.5e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH2 PF00017.24 OWF40904.1 - 1.6e-13 50.6 0.0 3.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SAM_2 PF07647.17 OWF40904.1 - 3e-11 43.2 0.0 7e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Exo_endo_phos PF03372.23 OWF40904.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATG16 PF08614.11 OWF40905.1 - 3.3e-46 158.0 25.2 3.3e-46 158.0 25.2 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 OWF40905.1 - 2.1e-31 107.5 22.0 9.6e-07 29.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF40905.1 - 2.4e-09 37.3 0.5 0.0008 19.7 0.0 4.8 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF40905.1 - 1.6e-06 28.2 0.0 0.26 11.2 0.0 3.4 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF40905.1 - 0.0015 17.5 0.1 1.4 7.8 0.1 3.5 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TMF_DNA_bd PF12329.8 OWF40905.1 - 0.0055 16.7 3.9 0.0055 16.7 3.9 3.9 3 1 1 4 4 4 2 TATA element modulatory factor 1 DNA binding WD40_like PF17005.5 OWF40905.1 - 0.076 12.3 0.0 6.1 6.1 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain ChaB PF06150.12 OWF40905.1 - 0.079 13.6 1.4 0.16 12.5 0.2 2.1 1 1 1 2 2 2 0 ChaB DUF4710 PF15828.5 OWF40905.1 - 0.87 9.7 3.8 0.81 9.8 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF4472 PF14739.6 OWF40905.1 - 1 10.1 27.0 0.38 11.5 9.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Cauli_AT PF03233.13 OWF40905.1 - 1.2 9.0 11.0 0.54 10.2 5.0 2.8 1 1 1 2 2 2 0 Aphid transmission protein OmpH PF03938.14 OWF40905.1 - 2.8 8.3 29.9 3.4 8.0 13.6 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PRKG1_interact PF15898.5 OWF40905.1 - 4 8.4 28.7 0.28 12.1 14.6 3.4 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 OWF40905.1 - 6.1 7.4 36.4 3.2e+03 -1.4 16.5 4.5 1 1 1 2 2 1 0 Cell division protein ZapB CENP-H PF05837.12 OWF40905.1 - 7.1 7.1 33.0 2.1 8.8 11.0 3.5 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 OWF40905.1 - 8.6 6.5 17.8 2 8.6 13.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 OWF40905.1 - 8.6 5.1 10.8 11 4.7 10.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 OWF40905.1 - 9.3 4.0 12.5 15 3.3 12.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PseudoU_synth_1 PF01416.20 OWF40906.1 - 1.1e-11 45.1 52.7 26 5.3 0.7 17.9 1 1 27 28 28 28 27 tRNA pseudouridine synthase CUE PF02845.16 OWF40907.1 - 5.8e-11 41.9 0.6 9e-11 41.3 0.6 1.3 1 0 0 1 1 1 1 CUE domain WD40 PF00400.32 OWF40908.1 - 1.1e-15 57.7 5.5 0.0006 20.6 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF40908.1 - 0.0097 16.2 0.0 44 4.5 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OWF40908.1 - 0.041 13.8 0.2 7.3 6.7 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RIX1 PF08167.12 OWF40909.1 - 1.3e-21 77.2 16.4 2.8e-20 72.9 0.4 3.6 4 0 0 4 4 4 3 rRNA processing/ribosome biogenesis NUC202 PF08166.12 OWF40909.1 - 0.00042 20.3 5.8 0.13 12.3 1.7 2.7 2 0 0 2 2 2 2 NUC202 domain DUF4110 PF13422.6 OWF40909.1 - 1.3 9.1 8.6 0.47 10.6 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Glyco_transf_22 PF03901.17 OWF40910.1 - 6.8e-32 111.2 7.3 7.1e-32 111.2 7.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Myb_DNA-bind_4 PF13837.6 OWF40911.1 - 7e-09 36.0 2.9 2.1e-08 34.4 0.1 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF3818 PF12825.7 OWF40911.1 - 0.14 11.1 2.2 0.2 10.6 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) UDG PF03167.19 OWF40914.1 - 8.4e-24 84.3 0.0 1.3e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ank_2 PF12796.7 OWF40915.1 - 7.6e-37 125.8 0.4 7.5e-11 42.5 0.0 9.4 4 4 7 12 12 12 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF40915.1 - 6.7e-16 58.2 0.0 6.3e-05 23.2 0.0 8.4 5 1 3 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF40915.1 - 9e-14 50.3 7.0 0.058 14.0 0.0 11.3 14 0 0 14 14 14 2 Ankyrin repeat Ank_4 PF13637.6 OWF40915.1 - 2.8e-12 46.9 0.5 0.00015 22.2 0.0 7.8 6 1 2 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF40915.1 - 8.1e-08 32.4 0.5 0.093 13.2 0.0 6.7 8 0 0 8 8 8 1 Ankyrin repeat ABC_tran PF00005.27 OWF40915.1 - 0.0012 19.4 0.0 0.0057 17.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter CheR PF01739.18 OWF40915.1 - 0.004 16.7 2.1 24 4.3 0.0 4.1 3 1 1 4 4 4 0 CheR methyltransferase, SAM binding domain NACHT PF05729.12 OWF40915.1 - 0.032 14.1 0.0 0.93 9.4 0.0 3.3 3 1 1 4 4 4 0 NACHT domain ResIII PF04851.15 OWF40915.1 - 0.061 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Exog_C PF18026.1 OWF40915.1 - 0.12 12.5 0.1 3 8.0 0.0 3.5 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain UDG PF03167.19 OWF40916.1 - 1.6e-06 28.2 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily zf-C2H2 PF00096.26 OWF40917.1 - 8e-09 35.5 24.1 0.00087 19.6 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF40917.1 - 3.5e-08 33.6 21.5 0.016 16.0 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF40917.1 - 0.001 19.4 25.7 0.076 13.5 0.2 4.8 5 0 0 5 5 5 2 Zinc-finger double domain SdrG_C_C PF10425.9 OWF40917.1 - 0.02 15.0 1.1 3 7.9 0.0 3.7 1 1 2 3 3 3 0 C-terminus of bacterial fibrinogen-binding adhesin Rep-A_N PF04057.12 OWF40917.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain zf-met PF12874.7 OWF40917.1 - 0.072 13.5 15.4 6.2 7.4 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 OWF40917.1 - 0.18 12.5 10.5 0.95 10.1 10.3 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 OWF40917.1 - 0.28 11.5 11.5 2.7 8.4 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF40917.1 - 0.4 10.7 20.5 0.57 10.3 4.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Actin_micro PF17003.5 OWF40917.1 - 1 8.4 12.8 0.56 9.3 9.7 1.9 1 1 1 2 2 2 0 Putative actin-like family zf_UBZ PF18439.1 OWF40917.1 - 1.2 8.8 6.5 9 6.0 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 OWF40917.1 - 2.1 8.6 11.2 0.15 12.3 2.0 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain PHD_4 PF16866.5 OWF40917.1 - 7.8 6.7 9.0 5 7.3 1.9 2.8 1 1 1 2 2 2 0 PHD-finger RRM_1 PF00076.22 OWF40918.1 - 7e-26 89.8 0.2 1.4e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OWF40918.1 - 0.002 18.4 0.1 0.98 9.6 0.1 3.1 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter AraC_binding PF02311.19 OWF40919.1 - 0.0038 17.1 1.3 11 5.9 0.0 5.1 2 2 1 5 5 5 1 AraC-like ligand binding domain RILP PF11461.8 OWF40919.1 - 0.0042 17.3 18.5 20 5.5 0.0 8.7 11 0 0 11 11 11 1 Rab interacting lysosomal protein TMEM190 PF15431.6 OWF40919.1 - 0.78 9.9 5.7 1.4e+02 2.6 0.0 5.4 2 2 4 6 6 6 0 Transmembrane protein 190 Autophagy_act_C PF03987.15 OWF40920.1 - 5.8e-12 46.0 35.9 93 3.7 0.1 16.5 1 1 1 2 2 2 1 Autophagocytosis associated protein, active-site domain DUF4203 PF13886.6 OWF40921.1 - 4.5e-43 147.3 38.3 5.4e-43 147.0 38.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Cyt_b-c1_8 PF10890.8 OWF40922.1 - 2e-05 24.9 5.1 57 4.2 0.1 7.5 1 1 7 8 8 8 0 Cytochrome b-c1 complex subunit 8 Nup35_RRM_2 PF14605.6 OWF40922.1 - 5.7e-05 23.0 51.2 2.2 8.4 0.4 10.9 6 4 5 11 11 11 7 Nup53/35/40-type RNA recognition motif KRTAP7 PF15034.6 OWF40922.1 - 0.0026 18.7 9.5 0.46 11.5 1.8 3.8 1 1 2 3 3 3 3 KRTAP type 7 family Phage_holin_2_3 PF16080.5 OWF40922.1 - 2 8.2 11.7 74 3.2 0.0 5.6 1 1 4 6 6 6 0 Bacteriophage holin family HP1 3A PF00803.18 OWF40923.1 - 8.3 5.6 11.1 38 3.5 1.1 3.6 1 1 3 4 4 4 0 3A/RNA2 movement protein family RNA_pol_Rpo13 PF12136.8 OWF40924.1 - 1.2 9.1 6.7 29 4.7 6.8 2.9 2 1 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain TTL PF03133.15 OWF40925.1 - 9.6e-97 323.7 0.2 1.8e-96 322.7 0.2 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF40925.1 - 7.3e-06 25.4 0.1 0.00039 19.8 0.0 2.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF40925.1 - 0.018 14.3 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RimK PF08443.11 OWF40925.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain GRAM PF02893.20 OWF40926.1 - 7.4e-06 25.8 0.4 2e-05 24.5 0.4 1.8 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 OWF40926.1 - 0.045 13.9 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DUF5089 PF17002.5 OWF40926.1 - 0.083 12.8 3.3 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) Spc7 PF08317.11 OWF40926.1 - 0.5 9.2 4.3 1.9 7.3 1.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein EAP30 PF04157.16 OWF40928.1 - 1.5e-63 214.2 0.1 2.1e-40 138.5 0.0 2.0 1 1 1 2 2 2 2 EAP30/Vps36 family CRM1_C PF08767.11 OWF40928.1 - 0.11 11.7 0.4 1.5 7.9 0.2 2.4 2 1 1 3 3 3 0 CRM1 C terminal Phage_Mu_Gam PF07352.12 OWF40928.1 - 0.3 11.0 4.5 0.19 11.7 2.5 1.6 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Methyltransf_21 PF05050.12 OWF40929.1 - 7.4e-12 45.6 0.1 1.3e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 OWF40929.1 - 0.00014 21.3 0.3 0.00024 20.5 0.3 1.4 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein DHC_N2 PF08393.13 OWF40929.1 - 0.0013 17.9 0.5 0.002 17.3 0.5 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 DUF4795 PF16043.5 OWF40929.1 - 0.0038 16.9 1.0 0.0073 15.9 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) SCP2 PF02036.17 OWF40929.1 - 0.0076 16.7 0.3 0.21 12.1 0.0 2.7 3 0 0 3 3 3 1 SCP-2 sterol transfer family DUF4094 PF13334.6 OWF40929.1 - 0.023 15.1 0.3 0.051 14.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Spc24 PF08286.11 OWF40929.1 - 0.024 14.8 5.8 3.2 8.1 2.2 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 OmpH PF03938.14 OWF40929.1 - 0.12 12.7 6.2 0.2 12.0 6.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CLN3 PF02487.17 OWF40929.1 - 0.17 10.9 2.5 0.26 10.3 2.5 1.1 1 0 0 1 1 1 0 CLN3 protein Snf7 PF03357.21 OWF40929.1 - 0.19 11.3 8.0 0.35 10.4 8.0 1.3 1 0 0 1 1 1 0 Snf7 GrpE PF01025.19 OWF40929.1 - 0.3 10.7 3.4 0.32 10.6 1.2 1.9 2 0 0 2 2 2 0 GrpE Nup88 PF10168.9 OWF40929.1 - 0.84 7.4 6.9 1.2 6.9 6.9 1.1 1 0 0 1 1 1 0 Nuclear pore component HEAT_UF PF18817.1 OWF40930.1 - 5.5e-05 23.3 12.4 50 4.3 0.1 8.9 4 3 6 10 10 10 1 Repeat of uncharacterized protein PH0542 Baculo_PEP_C PF04513.12 OWF40930.1 - 0.011 15.8 5.8 0.79 9.8 0.3 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DMT_YdcZ PF04657.13 OWF40930.1 - 0.28 11.5 16.6 9 6.6 0.8 5.3 1 1 4 6 6 6 0 Putative inner membrane exporter, YdcZ Beta_helix PF13229.6 OWF40931.1 - 3.9e-14 52.8 28.0 3.6e-08 33.4 13.0 3.4 3 1 1 4 4 4 2 Right handed beta helix region NosD PF05048.13 OWF40931.1 - 4.5e-05 22.8 19.8 6.6e-05 22.3 13.6 3.0 2 1 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Defensin_4 PF07936.12 OWF40931.1 - 0.055 13.3 6.7 0.75 9.7 0.1 3.2 3 0 0 3 3 3 0 Potassium-channel blocking toxin Pectate_lyase_3 PF12708.7 OWF40931.1 - 1.4 8.7 10.2 0.87 9.4 1.0 3.4 1 1 1 3 3 3 0 Pectate lyase superfamily protein Nt_Gln_amidase PF09764.9 OWF40932.1 - 3.9e-67 225.4 0.2 4.4e-67 225.3 0.2 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase NDUFB10 PF10249.9 OWF40932.1 - 0.063 13.8 0.5 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Isochorismatase PF00857.20 OWF40933.1 - 4e-26 92.2 0.4 6.7e-26 91.5 0.4 1.3 1 1 0 1 1 1 1 Isochorismatase family EF-hand_1 PF00036.32 OWF40934.1 - 3.1e-14 51.4 6.5 0.00017 20.9 0.2 4.1 2 2 2 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF40934.1 - 2.3e-11 44.0 8.3 0.0034 17.8 0.3 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF40934.1 - 1.4e-10 40.2 8.7 0.00081 19.1 0.5 3.7 2 2 2 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF40934.1 - 3.3e-08 33.2 4.2 0.0041 16.9 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF40934.1 - 2.7e-05 23.5 7.4 0.004 16.6 0.2 3.4 2 2 2 4 4 4 2 EF hand Dockerin_1 PF00404.18 OWF40934.1 - 0.0014 18.8 0.3 0.24 11.6 0.1 3.1 2 1 2 4 4 4 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OWF40934.1 - 0.002 18.4 4.4 0.25 11.7 1.9 3.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF40934.1 - 0.005 16.8 1.6 2.8 8.0 0.2 2.4 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OWF40934.1 - 0.045 14.6 0.3 28 5.7 0.0 2.6 1 1 1 3 3 3 0 EF-hand domain CCD48 PF15799.5 OWF40934.1 - 0.23 9.8 0.0 0.3 9.4 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 RRM_1 PF00076.22 OWF40935.1 - 1.1e-32 111.6 0.5 4.8e-16 58.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF40935.1 - 8.6e-11 41.8 0.3 0.00034 20.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OWF40935.1 - 0.02 14.9 0.2 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif NID PF07292.13 OWF40935.1 - 0.049 14.3 0.3 3.9 8.2 0.1 2.7 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) PHM7_cyt PF14703.6 OWF40935.1 - 0.24 11.6 0.7 5.5 7.2 0.0 2.5 2 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Gifsy-2 PF13856.6 OWF40936.1 - 0.13 12.6 3.5 0.25 11.7 0.9 2.9 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage HTH_Tnp_Mu_2 PF09039.11 OWF40937.1 - 6.7e-07 29.4 1.7 4.4 7.4 0.1 4.3 1 1 3 4 4 4 4 Mu DNA binding, I gamma subdomain L51_S25_CI-B8 PF05047.16 OWF40937.1 - 2.7e-06 27.2 0.0 5.9 6.9 0.0 5.9 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DDE_3 PF13358.6 OWF40937.1 - 4e-06 26.7 0.1 5.9 6.6 0.0 3.9 1 1 3 4 4 4 4 DDE superfamily endonuclease DUF1910 PF08928.10 OWF40937.1 - 9e-06 25.7 10.1 38 4.3 0.0 7.9 1 1 10 12 12 12 0 Domain of unknown function (DUF1910) NUC205 PF08168.11 OWF40937.1 - 2e-05 24.0 0.1 18 4.9 0.0 5.1 1 1 5 6 6 6 0 NUC205 domain TTRAP PF14203.6 OWF40937.1 - 0.00079 19.4 0.1 62 3.7 0.0 5.1 1 1 3 5 5 5 0 Putative tranposon-transfer assisting protein MgtE_N PF03448.17 OWF40937.1 - 0.00091 19.8 0.1 3.6 8.2 0.0 2.5 1 1 0 2 2 2 2 MgtE intracellular N domain Acyl_transf_1 PF00698.21 OWF40937.1 - 1.5 8.2 15.5 8.1 5.8 2.4 3.1 1 1 2 3 3 3 0 Acyl transferase domain DUF4892 PF16234.5 OWF40937.1 - 1.5 8.2 20.7 9.4 5.7 0.7 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4892) CATSPERD PF15020.6 OWF40937.1 - 1.5 7.0 4.7 9.6 4.3 0.3 2.4 1 1 0 2 2 2 0 Cation channel sperm-associated protein subunit delta V_ATPase_I PF01496.19 OWF40938.1 - 0.3 8.9 7.6 0.023 12.6 0.6 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3987 PF13148.6 OWF40939.1 - 4e-19 68.9 0.0 3.5e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AT_hook PF02178.19 OWF40940.1 - 7.9 6.7 21.5 2.9 8.1 7.3 3.1 2 0 0 2 2 2 0 AT hook motif DUF2850 PF11012.8 OWF40941.1 - 6.6e-05 23.1 0.2 6.5 7.1 0.1 4.2 1 1 3 5 5 5 1 Protein of unknown function (DUF2850) Inhibitor_I24 PF10465.9 OWF40941.1 - 0.00011 22.2 2.5 9.5 6.2 0.1 3.9 1 1 3 4 4 4 3 PinA peptidase inhibitor Limkain-b1 PF11608.8 OWF40941.1 - 0.0035 17.4 1.9 16 5.6 0.0 4.5 1 1 2 4 4 4 1 Limkain b1 GalKase_gal_bdg PF10509.9 OWF40941.1 - 0.012 15.1 0.1 13 5.4 0.0 3.5 3 1 1 4 4 4 0 Galactokinase galactose-binding signature Rimk_N PF18030.1 OWF40941.1 - 0.02 15.3 1.3 8.5 6.8 0.1 3.4 1 1 3 4 4 4 0 RimK PreATP-grasp domain YcgR_2 PF12945.7 OWF40941.1 - 0.022 14.9 0.3 16 5.7 0.0 3.2 3 1 1 4 4 4 0 Flagellar protein YcgR DUF2185 PF09951.9 OWF40941.1 - 0.054 13.3 0.1 12 5.8 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2185) CTV_P6 PF06706.11 OWF40941.1 - 0.14 11.9 13.0 11 5.8 0.2 5.4 1 1 6 7 7 7 0 Citrus tristeza virus 6-kDa protein DnaJ_CXXCXGXG PF00684.19 OWF40941.1 - 0.24 11.8 4.3 3.6 8.0 4.3 2.5 1 1 0 1 1 1 0 DnaJ central domain Pro_3_hydrox_C PF05373.11 OWF40943.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.6 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal IL2 PF00715.17 OWF40944.1 - 0.08 12.9 2.3 0.2 11.6 1.8 2.0 1 1 0 1 1 1 0 Interleukin 2 DsrC PF04358.13 OWF40944.1 - 1.8 9.1 6.1 0.33 11.5 0.1 2.9 4 0 0 4 4 4 0 DsrC like protein VIT PF08487.10 OWF40945.1 - 1.1e-42 144.7 0.0 2.8e-42 143.4 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 OWF40945.1 - 1.1e-26 93.6 0.1 1.9e-25 89.6 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain PARP PF00644.20 OWF40945.1 - 8.4e-24 84.2 0.3 8.4e-24 84.2 0.3 3.4 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain VWA PF00092.28 OWF40945.1 - 2.3e-13 50.8 0.1 7.8e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain ubiquitin PF00240.23 OWF40945.1 - 2.3e-13 49.7 0.0 2.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family VIT_2 PF13757.6 OWF40945.1 - 4.2e-13 49.0 0.0 9.6e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 OWF40945.1 - 6e-09 36.5 0.0 2.1e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain BRCT_2 PF16589.5 OWF40945.1 - 5.5e-07 29.9 0.2 4.3e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OWF40945.1 - 2.2e-05 24.8 0.0 0.00016 22.0 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rad60-SLD PF11976.8 OWF40945.1 - 3.6e-05 23.5 0.0 0.0001 22.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Slu7 PF11708.8 OWF40945.1 - 0.02 14.6 0.1 0.02 14.6 0.1 3.8 3 0 0 3 3 2 0 Pre-mRNA splicing Prp18-interacting factor Ubiquitin_2 PF14560.6 OWF40945.1 - 0.034 14.6 1.1 0.079 13.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain CENP-B_dimeris PF09026.10 OWF40945.1 - 0.063 13.7 13.4 0.26 11.7 13.4 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF5427 PF10310.9 OWF40945.1 - 7.4 5.4 16.9 0.23 10.4 0.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Pyr_redox_2 PF07992.14 OWF40946.1 - 7.4e-51 173.1 0.0 8.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF40946.1 - 8.9e-10 39.0 0.1 6.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF40946.1 - 0.0049 16.9 0.0 1.3 9.0 0.0 2.6 1 1 1 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF40946.1 - 0.033 14.4 0.0 8.3 6.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OWF40946.1 - 0.038 13.2 0.1 2.1 7.5 0.1 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF40946.1 - 0.072 12.1 0.1 0.86 8.6 0.0 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 OWF40946.1 - 0.12 11.4 0.2 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A MafB19-deam PF14437.6 OWF40947.1 - 1.2e-20 73.6 0.1 2.2e-20 72.8 0.1 1.4 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 OWF40947.1 - 1.3e-19 70.0 0.2 1.8e-19 69.5 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC3 PF18771.1 OWF40947.1 - 0.0013 18.8 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 OWF40947.1 - 0.0027 17.8 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 OWF40947.1 - 0.004 17.2 0.0 0.0051 16.9 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 OWF40947.1 - 0.0045 17.1 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 OWF40947.1 - 0.005 16.9 1.2 0.064 13.3 1.2 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase NAD2 PF18782.1 OWF40947.1 - 0.057 13.5 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 OWF40947.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 OWF40947.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Fe_bilin_red PF05996.12 OWF40948.1 - 0.011 15.5 0.3 0.053 13.2 0.9 1.8 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase Cas6b_C PF17262.2 OWF40948.1 - 0.083 13.0 0.7 15 5.7 0.2 2.4 1 1 1 2 2 2 0 Cas6b C-terminal domain Atg14 PF10186.9 OWF40948.1 - 0.12 11.4 0.1 0.12 11.4 0.1 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 LptF_LptG PF03739.14 OWF40948.1 - 0.19 10.6 1.5 0.25 10.2 1.5 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG MIEAP PF16026.5 OWF40948.1 - 0.38 11.0 6.3 0.94 9.7 6.3 1.7 1 0 0 1 1 1 0 Mitochondria-eating protein DUF5082 PF16888.5 OWF40948.1 - 0.63 10.3 13.5 0.44 10.8 10.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Bin3 PF06859.12 OWF40948.1 - 0.81 10.4 6.5 0.57 10.8 3.7 2.2 2 1 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) IML1 PF12257.8 OWF40949.1 - 1.5e-110 368.8 1.8 3.1e-110 367.8 0.1 2.1 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 OWF40949.1 - 2.5e-09 37.0 0.0 6.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_transf_22 PF03901.17 OWF40950.1 - 3.7e-25 89.0 30.0 2.3e-12 46.9 13.4 3.1 3 0 0 3 3 3 3 Alg9-like mannosyltransferase family TPR_19 PF14559.6 OWF40950.1 - 0.0091 16.5 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF420 PF04238.12 OWF40950.1 - 2.7 8.3 13.6 0.28 11.5 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF420) PHD PF00628.29 OWF40951.1 - 8.5e-18 64.0 24.3 6.9e-10 38.7 13.1 2.5 2 0 0 2 2 2 2 PHD-finger PHF12_MRG_bd PF16737.5 OWF40951.1 - 6.2e-16 57.8 0.1 1.2e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain PHD_2 PF13831.6 OWF40951.1 - 1.7e-05 24.2 11.3 0.0052 16.3 2.5 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 OWF40951.1 - 0.00025 20.9 15.1 0.0021 17.9 1.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FHA PF00498.26 OWF40951.1 - 0.014 15.7 0.0 0.048 14.0 0.0 1.9 1 0 0 1 1 1 0 FHA domain zf-PHD-like PF15446.6 OWF40951.1 - 0.66 9.6 9.1 2.3 7.8 1.1 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain CDP-OH_P_transf PF01066.21 OWF40954.1 - 1.5e-11 44.9 0.3 1.5e-11 44.9 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-CCHC PF00098.23 OWF40955.1 - 6e-36 120.9 78.6 3e-05 23.9 3.5 9.9 8 1 1 9 9 9 9 Zinc knuckle zf-CCHC_4 PF14392.6 OWF40955.1 - 7.2e-09 35.2 58.7 0.0082 15.9 0.8 9.1 3 3 6 9 9 9 7 Zinc knuckle zf-CCHC_2 PF13696.6 OWF40955.1 - 7.1e-06 25.7 71.9 0.0052 16.6 3.2 9.2 9 0 0 9 9 9 8 Zinc knuckle zf-CCHC_5 PF14787.6 OWF40955.1 - 0.00024 20.7 55.6 0.033 13.9 1.8 7.7 3 1 4 7 7 7 5 GAG-polyprotein viral zinc-finger DUF4490 PF14892.6 OWF40955.1 - 0.033 14.2 0.0 11 6.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4490) TSP_3 PF02412.18 OWF40955.1 - 0.36 10.6 3.6 24 4.7 0.1 3.7 4 0 0 4 4 4 0 Thrombospondin type 3 repeat EMG1 PF03587.14 OWF40956.1 - 2e-86 288.6 0.1 2.4e-86 288.4 0.1 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase FliS PF02561.14 OWF40957.1 - 0.061 13.6 0.2 0.2 11.9 0.2 1.9 1 0 0 1 1 1 0 Flagellar protein FliS Phosphonate-bd PF12974.7 OWF40959.1 - 2.6e-32 112.4 0.0 3.2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 OWF40959.1 - 0.0027 17.1 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 GIDE PF12483.8 OWF40960.1 - 1.3e-22 79.9 0.1 6.6e-22 77.6 0.1 2.0 2 0 0 2 2 2 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 OWF40960.1 - 2.4e-11 43.3 8.9 4.1e-11 42.6 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF40960.1 - 4.1e-08 33.0 9.6 6.9e-08 32.2 9.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF40960.1 - 0.00044 20.1 8.0 0.0011 18.9 8.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF40960.1 - 0.005 17.1 11.3 0.0097 16.2 11.3 1.5 1 0 0 1 1 1 1 Ring finger domain Mx_ML PF17536.2 OWF40960.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal CBM_20 PF00686.19 OWF40961.1 - 4.1e-13 49.0 0.4 6.9e-13 48.3 0.4 1.5 1 0 0 1 1 1 1 Starch binding domain Dynein_light PF01221.18 OWF40962.1 - 3.9e-41 139.2 1.6 4.4e-41 139.1 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RP853 PF17542.2 OWF40962.1 - 0.013 14.6 0.2 0.013 14.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 Imm48 PF15574.6 OWF40962.1 - 0.028 14.2 0.3 0.052 13.3 0.3 1.5 1 1 0 1 1 1 0 Immunity protein 48 Organ_specific PF10950.8 OWF40962.1 - 0.075 13.7 0.1 0.085 13.6 0.1 1.1 1 0 0 1 1 1 0 Organ specific protein Ectatomin PF06457.11 OWF40962.1 - 0.16 11.9 0.3 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 Ectatomin Dynein_light PF01221.18 OWF40963.1 - 1.4e-41 140.7 1.7 1.7e-41 140.4 1.7 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 CopB PF05275.11 OWF40963.1 - 0.078 12.5 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) Dynein_light PF01221.18 OWF40964.1 - 9.6e-42 141.2 1.4 1.1e-41 141.1 1.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 OWF40964.1 - 0.18 11.7 0.3 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 Ectatomin Cpn60_TCP1 PF00118.24 OWF40965.1 - 8.5e-167 555.7 9.1 9.6e-167 555.5 9.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FAD_binding_1 PF00667.20 OWF40966.1 - 9.4e-73 244.4 0.0 2.5e-72 243.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 OWF40966.1 - 7.4e-36 123.5 1.5 2.3e-35 121.9 1.5 1.9 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OWF40966.1 - 8e-18 65.1 0.0 7.7e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain AAA_25 PF13481.6 OWF40967.1 - 1.1e-22 80.5 0.0 1.9e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 OWF40967.1 - 4.8e-11 42.5 0.0 8.3e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 OWF40967.1 - 2.2e-07 31.2 0.0 5.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OWF40967.1 - 5.7e-07 29.1 0.0 1.6e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_16 PF13191.6 OWF40967.1 - 0.0004 20.8 0.0 0.00085 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OWF40967.1 - 0.0042 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OWF40967.1 - 0.0074 15.4 0.0 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 OWF40967.1 - 0.021 15.3 0.1 0.021 15.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OWF40967.1 - 0.05 14.1 0.4 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 OWF40967.1 - 0.082 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OWF40967.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Toxin_2 PF00451.19 OWF40968.1 - 0.0053 17.0 5.5 0.0053 17.0 5.5 2.5 2 1 0 2 2 2 1 Scorpion short toxin, BmKK2 Squash PF00299.18 OWF40968.1 - 0.023 14.7 1.3 0.023 14.7 1.3 3.5 2 1 0 2 2 2 0 Squash family serine protease inhibitor Nodulin_late PF07127.11 OWF40968.1 - 0.8 10.1 19.9 0.21 12.0 3.9 2.8 2 1 0 2 2 2 0 Late nodulin protein Toxin_2 PF00451.19 OWF40969.1 - 4.3 7.7 22.3 1 9.7 8.6 2.5 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Kinesin PF00225.23 OWF40970.1 - 2.4e-95 319.3 0.0 3.4e-95 318.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF40970.1 - 5.3e-21 75.1 0.0 1.5e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding UPF0449 PF15136.6 OWF40970.1 - 1.5 9.3 7.6 5.7 7.5 5.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 PikAIV_N PF18605.1 OWF40970.1 - 2.7 7.6 4.8 0.92 9.1 0.1 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CCDC92 PF14916.6 OWF40970.1 - 3.8 7.3 6.6 1.7 8.4 1.1 3.0 2 1 1 3 3 3 0 Coiled-coil domain of unknown function YabA PF06156.13 OWF40970.1 - 4.2 8.1 18.3 3.1 8.5 2.6 3.7 3 0 0 3 3 3 0 Initiation control protein YabA DUF1168 PF06658.12 OWF40971.1 - 3.4e-41 140.2 16.5 4.7e-41 139.8 16.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4775 PF16001.5 OWF40971.1 - 0.11 11.9 19.4 0.15 11.4 19.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) MAJIN PF15077.6 OWF40971.1 - 0.93 9.2 11.6 1.5 8.5 11.6 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Eapp_C PF10238.9 OWF40971.1 - 4.3 7.4 8.6 6.4 6.8 8.6 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Ion_trans PF00520.31 OWF40972.1 - 2.7e-10 39.9 5.7 3.9e-10 39.4 5.7 1.2 1 0 0 1 1 1 1 Ion transport protein VGPC1_C PF16799.5 OWF40972.1 - 0.065 13.2 0.5 0.17 11.9 0.5 1.7 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF2381 PF09544.10 OWF40972.1 - 0.12 11.9 0.4 0.16 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DUF5336 PF17270.2 OWF40972.1 - 0.51 10.0 1.4 1.9 8.1 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) DUF5083 PF16890.5 OWF40972.1 - 1.1 9.0 5.9 1.7 8.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Thioredoxin_4 PF13462.6 OWF40973.1 - 1.7e-07 31.5 0.0 2.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OWF40973.1 - 0.0036 17.1 0.0 0.15 11.9 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Phosphodiest PF01663.22 OWF40973.1 - 0.0051 16.5 0.0 0.0066 16.1 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase UPF0149 PF03695.13 OWF40973.1 - 0.0085 16.4 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) CPSase_L_D2 PF02786.17 OWF40975.1 - 4.9e-76 254.9 0.2 8.3e-76 254.2 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OWF40975.1 - 2e-35 121.1 0.0 5.3e-35 119.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OWF40975.1 - 3.8e-25 88.6 0.4 6e-23 81.5 0.1 2.7 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OWF40975.1 - 7.8e-14 51.3 4.1 7.8e-14 51.3 4.1 2.9 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OWF40975.1 - 3e-12 46.5 0.0 1e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OWF40975.1 - 7e-09 35.5 0.2 1.4e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OWF40975.1 - 1.3e-06 28.1 2.4 0.0022 17.8 0.0 3.1 3 0 0 3 3 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 OWF40975.1 - 1.1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OWF40975.1 - 0.00011 21.9 0.1 0.0023 17.5 0.0 2.6 2 1 0 2 2 2 1 RimK-like ATP-grasp domain RnfC_N PF13375.6 OWF40975.1 - 0.00021 21.2 0.3 0.00061 19.7 0.3 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 OWF40975.1 - 0.00029 21.5 1.2 1.4 9.7 0.1 3.1 3 0 0 3 3 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 OWF40975.1 - 0.0026 17.0 0.2 2.3 7.4 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 OWF40975.1 - 0.0045 16.3 0.0 0.21 10.8 0.0 2.4 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF3182 PF11379.8 OWF40975.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) CarboxypepD_reg PF13620.6 OWF40975.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Ntox43 PF15537.6 OWF40975.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 43 GARS_A PF01071.19 OWF40975.1 - 0.034 13.9 0.1 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 OWF40975.1 - 0.067 12.6 0.5 0.16 11.4 0.5 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF3823 PF12866.7 OWF40975.1 - 0.08 13.2 0.1 0.72 10.2 0.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain YqfD PF06898.11 OWF40975.1 - 0.11 11.3 1.9 3.8 6.2 0.1 2.3 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD p450 PF00067.22 OWF40976.1 - 6.6e-119 397.7 0.0 7.5e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arm PF00514.23 OWF40977.1 - 7.3e-22 76.7 22.9 0.00023 21.1 0.1 8.4 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OWF40977.1 - 3.4e-10 40.2 6.3 0.026 15.0 0.0 5.6 5 1 1 7 7 7 3 HEAT-like repeat Arm_3 PF16186.5 OWF40977.1 - 3.9e-08 32.7 0.1 9e-08 31.6 0.1 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 OWF40977.1 - 7.7e-08 32.6 4.2 0.0058 17.0 0.1 4.8 3 1 4 7 7 7 4 HEAT repeats IBB PF01749.20 OWF40977.1 - 1.3e-06 28.7 5.5 2.7e-06 27.7 5.5 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 OWF40977.1 - 5.8e-06 26.1 9.8 0.099 13.0 0.0 6.3 8 0 0 8 8 7 2 HEAT repeat NopRA1 PF16201.5 OWF40977.1 - 4.4e-05 23.1 0.9 0.014 15.0 0.0 3.7 2 1 3 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 Cnd1 PF12717.7 OWF40977.1 - 0.00011 22.2 0.0 0.0018 18.4 0.0 2.5 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OWF40977.1 - 0.0024 16.5 0.6 0.0098 14.5 0.4 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.9 OWF40977.1 - 0.019 13.5 0.2 1.1 7.7 0.0 2.6 1 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit RIH_assoc PF08454.11 OWF40977.1 - 0.038 13.8 0.4 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 RyR and IP3R Homology associated Arm_2 PF04826.13 OWF40977.1 - 0.097 12.1 0.1 4.4 6.7 0.1 2.9 1 1 2 3 3 3 0 Armadillo-like Mnd1 PF03962.15 OWF40978.1 - 1.2e-24 86.3 0.1 3.7e-24 84.8 0.1 1.8 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 OWF40978.1 - 1.8e-22 79.2 1.3 1.8e-22 79.2 1.3 2.5 3 0 0 3 3 3 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 OWF40978.1 - 5.8e-05 23.4 0.7 0.00011 22.5 0.7 1.4 1 0 0 1 1 1 1 Penicillinase repressor ABC_tran_CTD PF16326.5 OWF40978.1 - 0.43 10.9 4.2 0.54 10.5 2.6 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain DivIVA PF05103.13 OWF40978.1 - 0.64 10.1 6.0 2.8 8.0 6.1 1.8 1 1 1 2 2 2 0 DivIVA protein CARD PF00619.21 OWF40979.1 - 8.1e-08 32.2 0.1 1.4e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF40979.1 - 3.9e-05 23.6 0.0 0.0005 20.0 0.0 2.1 2 0 0 2 2 2 1 Caspase recruitment domain Death PF00531.22 OWF40979.1 - 5.3e-05 23.3 0.0 0.0002 21.5 0.0 1.9 2 0 0 2 2 2 1 Death domain DUF3199 PF11436.8 OWF40979.1 - 0.034 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) zf-RING_UBOX PF13445.6 OWF40980.1 - 0.00076 19.5 2.0 0.0015 18.5 2.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger CARD PF00619.21 OWF40981.1 - 4.8e-08 32.9 0.1 8.9e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF40981.1 - 9.2e-06 25.6 0.1 0.00023 21.1 0.1 2.6 2 1 0 2 2 2 1 Caspase recruitment domain Death PF00531.22 OWF40981.1 - 0.00063 19.9 0.0 0.0032 17.6 0.0 2.1 2 0 0 2 2 2 1 Death domain DED PF01335.21 OWF40981.1 - 0.074 13.4 0.3 0.35 11.2 0.3 2.1 1 1 0 1 1 1 0 Death effector domain ABC2_membrane PF01061.24 OWF40982.1 - 7.7e-18 64.7 5.5 7.7e-18 64.7 5.5 2.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OWF40982.1 - 1.3e-09 38.7 0.0 2.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF40982.1 - 0.0095 15.8 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OWF40982.1 - 0.24 11.6 0.3 2.9 8.2 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 OWF40983.1 - 2.8e-29 102.4 0.0 4.6e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OWF40983.1 - 4.6e-28 98.1 12.7 6.7e-28 97.5 12.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 OWF40983.1 - 3e-06 27.3 0.1 0.0016 18.3 0.0 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OWF40983.1 - 0.00024 20.2 0.2 0.0004 19.5 0.2 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OWF40983.1 - 0.00025 21.0 0.2 0.00045 20.2 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 OWF40983.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OWF40983.1 - 0.015 15.0 0.1 0.036 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OWF40983.1 - 0.032 14.3 0.3 0.097 12.7 0.3 1.9 1 1 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 OWF40983.1 - 0.037 14.3 0.1 0.13 12.5 0.0 1.9 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 OWF40983.1 - 0.074 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 OWF40983.1 - 0.088 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 OWF40983.1 - 0.089 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 OWF40983.1 - 0.091 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DUF87 PF01935.17 OWF40983.1 - 0.12 12.4 0.7 0.6 10.1 0.3 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OWF40983.1 - 0.15 12.5 0.3 0.32 11.5 0.3 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OWF40983.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 OWF40983.1 - 0.21 11.4 1.0 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OWF40983.1 - 0.25 11.1 0.6 2.4 7.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Carb_anhydrase PF00194.21 OWF40984.1 - 3.2e-19 69.5 0.0 3.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 OWF40985.1 - 6.3e-82 274.9 0.2 7.3e-82 274.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ependymin PF00811.18 OWF40986.1 - 1.5e-11 44.7 0.9 1.5e-11 44.7 0.9 1.5 2 0 0 2 2 2 1 Ependymin Carb_anhydrase PF00194.21 OWF40987.1 - 1.4e-78 264.0 0.3 1.4e-78 264.0 0.3 4.1 2 1 1 3 3 3 1 Eukaryotic-type carbonic anhydrase 7tm_1 PF00001.21 OWF40988.1 - 1.5e-50 172.0 13.5 1.9e-50 171.6 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF40988.1 - 8.8e-17 61.3 12.1 1.2e-16 60.9 12.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF40988.1 - 5.4e-15 55.7 15.6 8.1e-15 55.2 15.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF40988.1 - 7.3e-06 25.9 17.9 0.00012 22.0 17.9 2.5 1 1 0 1 1 1 1 Olfactory receptor TAS2R PF05296.13 OWF40988.1 - 1.4e-05 24.3 3.7 1.4e-05 24.3 3.7 2.1 2 1 0 2 2 2 1 Taste receptor protein (TAS2R) DUF3169 PF11368.8 OWF40988.1 - 0.0026 17.3 3.6 0.0026 17.3 3.6 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF3169) YajC PF02699.15 OWF40988.1 - 0.13 12.1 2.8 0.53 10.2 0.1 2.7 2 0 0 2 2 2 0 Preprotein translocase subunit 7TM_GPCR_Srt PF10321.9 OWF40988.1 - 6.4 5.7 19.9 0.57 9.1 12.1 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt 7tm_1 PF00001.21 OWF40989.1 - 6.2e-56 189.6 8.1 8e-56 189.3 8.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF40989.1 - 1e-16 61.4 12.9 1.4e-16 60.9 12.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF40989.1 - 1.8e-15 57.0 7.1 2.6e-15 56.5 7.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF40989.1 - 5.4e-09 36.2 9.2 2.7e-08 33.9 9.2 2.1 1 1 0 1 1 1 1 Olfactory receptor HEV_ORF1 PF02444.16 OWF40989.1 - 0.011 16.3 4.6 0.012 16.1 3.4 1.8 1 1 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) 7TM_GPCR_Srt PF10321.9 OWF40989.1 - 5.4 5.9 17.7 15 4.4 17.6 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt 7tm_1 PF00001.21 OWF40990.1 - 2.6e-54 184.3 8.0 3.5e-54 183.9 8.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF40990.1 - 1.4e-15 57.6 10.7 2e-15 57.1 10.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF40990.1 - 1.5e-15 57.3 6.5 2.5e-15 56.5 6.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF40990.1 - 2.4e-08 34.0 9.5 1.6e-07 31.3 9.5 2.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 OWF40990.1 - 1.8e-07 30.9 6.5 3.1e-07 30.1 6.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF3169 PF11368.8 OWF40990.1 - 0.0034 16.9 2.8 0.0034 16.9 2.8 2.7 2 1 0 3 3 3 1 Protein of unknown function (DUF3169) CTV_P6 PF06706.11 OWF40990.1 - 1.2 8.9 5.0 12 5.7 0.1 3.1 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein 7TM_GPCR_Srt PF10321.9 OWF40990.1 - 6.9 5.5 15.1 0.81 8.6 8.3 2.2 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt HD-ZIP_N PF04618.12 OWF40991.1 - 2.6 8.6 7.6 0.6 10.6 2.0 2.5 2 1 0 2 2 2 0 HD-ZIP protein N terminus DUF716 PF04819.12 OWF40992.1 - 3.9e-11 42.8 10.4 2e-10 40.4 10.4 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF716) MORN PF02493.20 OWF40993.1 - 7e-28 94.8 42.8 1.2e-05 24.9 1.2 7.4 7 0 0 7 7 7 6 MORN repeat DUF3048_C PF17479.2 OWF40993.1 - 0.011 16.1 15.8 3.1 8.2 2.1 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Orai-1 PF07856.12 OWF40994.1 - 3e-60 202.9 9.6 3.6e-60 202.6 9.6 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity SKG6 PF08693.10 OWF40994.1 - 0.012 15.1 0.3 0.031 13.7 0.3 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF202 PF02656.15 OWF40994.1 - 2.4 8.7 11.0 0.11 13.0 2.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PHD_4 PF16866.5 OWF40995.1 - 5e-23 81.0 10.2 5e-23 81.0 10.2 2.3 2 0 0 2 2 2 1 PHD-finger zf-CXXC PF02008.20 OWF40995.1 - 7e-13 48.4 21.4 7e-13 48.4 21.4 2.1 2 0 0 2 2 2 1 CXXC zinc finger domain F-box-like PF12937.7 OWF40995.1 - 4.5e-08 32.8 1.5 1.1e-07 31.6 1.5 1.7 1 0 0 1 1 1 1 F-box-like JmjC PF02373.22 OWF40995.1 - 5.9e-06 26.7 0.4 0.00042 20.7 0.4 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OWF40995.1 - 9.2e-06 25.5 3.4 2.1e-05 24.4 0.2 2.7 2 1 0 2 2 2 1 Cupin-like domain JHD PF17811.1 OWF40995.1 - 1.2e-05 25.7 0.2 3.4e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 Jumonji helical domain F-box PF00646.33 OWF40995.1 - 8.7e-05 22.3 0.2 0.00024 20.9 0.2 1.8 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 OWF40995.1 - 0.0036 17.2 1.0 3.3 8.0 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 OWF40995.1 - 0.031 14.7 3.1 0.077 13.5 0.0 3.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Ion_trans PF00520.31 OWF40996.1 - 1.2e-29 103.2 19.5 1.2e-29 103.2 19.5 1.4 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.22 OWF40996.1 - 5.9e-24 84.2 0.0 3.6e-23 81.7 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF40996.1 - 3.6e-10 39.7 7.1 3.6e-10 39.7 7.1 2.8 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 OWF40996.1 - 0.00071 19.7 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF2525 PF10733.9 OWF40996.1 - 0.28 11.5 0.6 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) DUF2975 PF11188.8 OWF40996.1 - 1.2 9.0 14.8 0.03 14.2 6.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) SRAP PF02586.14 OWF40997.1 - 0.003 17.1 36.4 3 7.3 0.2 8.9 1 1 5 6 6 6 3 SOS response associated peptidase (SRAP) Serpulina_VSP PF05540.11 OWF40997.1 - 0.023 13.8 17.9 1.6 7.7 2.0 4.7 1 1 2 4 4 4 0 Serpulina hyodysenteriae variable surface protein GST_N_3 PF13417.6 OWF40997.1 - 0.026 14.9 25.3 31 5.1 0.1 8.8 3 2 7 10 10 10 0 Glutathione S-transferase, N-terminal domain Sld7_C PF18596.1 OWF40997.1 - 0.062 13.4 4.8 5.8 7.1 0.4 3.0 1 1 1 2 2 2 0 Sld7 C-terminal domain GST_N_2 PF13409.6 OWF40997.1 - 0.15 12.4 25.5 40 4.6 0.2 8.3 1 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain SRAP PF02586.14 OWF40998.1 - 0.0029 17.2 4.6 3.6 7.1 4.6 2.6 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) DUF4986 PF16375.5 OWF40998.1 - 0.0098 16.6 0.1 1.2 9.9 0.0 2.8 1 1 1 3 3 3 1 Domain of unknown function GST_N_2 PF13409.6 OWF40998.1 - 0.036 14.4 0.8 8.3 6.8 0.0 2.3 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF40998.1 - 0.057 13.8 0.8 5 7.6 0.7 2.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain p6 PF17548.2 OWF40998.1 - 0.062 13.3 0.0 13 5.8 0.0 2.5 2 1 1 3 3 3 0 Histone-like Protein p6 DUF3909 PF13077.6 OWF40998.1 - 0.3 11.2 2.0 37 4.5 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3909) DUF2520 PF10728.9 OWF40998.1 - 0.43 10.3 5.7 0.94 9.3 0.3 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF2520) UFD1 PF03152.14 OWF40999.1 - 1e-77 259.5 0.0 1.3e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 OWF40999.1 - 0.083 13.1 0.0 0.87 9.8 0.0 2.2 1 1 2 3 3 3 0 Cell division protein 48 (CDC48), N-terminal domain Tenui_PVC2 PF06656.11 OWF40999.1 - 0.23 9.3 0.0 0.33 8.8 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein CDC45 PF02724.14 OWF41000.1 - 6e-120 401.5 8.0 5.7e-108 361.9 5.0 3.0 1 1 1 2 2 2 2 CDC45-like protein Tektin PF03148.14 OWF41001.1 - 4.9e-154 512.7 34.4 5.5e-154 512.5 34.4 1.0 1 0 0 1 1 1 1 Tektin family DUF948 PF06103.11 OWF41001.1 - 0.011 15.9 15.5 1.6 9.1 0.4 4.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 OWF41001.1 - 0.029 14.4 19.0 0.71 9.9 3.5 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OWF41001.1 - 0.12 12.5 21.8 0.75 9.9 0.3 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 OWF41001.1 - 0.13 11.8 25.2 0.21 11.1 8.4 2.2 1 1 0 2 2 2 0 Exonuclease VII, large subunit Laminin_II PF06009.12 OWF41001.1 - 0.57 10.2 24.6 1.1 9.3 3.6 4.3 2 2 0 4 4 4 0 Laminin Domain II DUF892 PF05974.12 OWF41001.1 - 1.1 9.2 13.6 0.15 12.0 1.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF892) Osmo_CC PF08946.10 OWF41001.1 - 1.3 9.3 9.7 4 7.7 1.4 3.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil MCPsignal PF00015.21 OWF41001.1 - 1.3 8.8 12.5 0.13 12.1 1.0 3.4 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MitMem_reg PF13012.6 OWF41001.1 - 2.5 8.6 10.8 3.7e+03 -1.6 10.8 4.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Fzo_mitofusin PF04799.13 OWF41001.1 - 2.6 7.6 22.6 0.045 13.3 3.9 3.9 3 1 0 4 4 4 0 fzo-like conserved region ApoLp-III PF07464.11 OWF41001.1 - 3.4 7.8 22.0 4 7.5 0.5 4.2 2 2 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) PXA PF02194.15 OWF41001.1 - 3.5 7.6 7.5 1.5 8.8 3.5 2.3 1 1 1 2 2 2 0 PXA domain YtxH PF12732.7 OWF41001.1 - 4 8.1 14.1 8.8 6.9 0.5 4.1 3 1 1 4 4 4 0 YtxH-like protein Nsp1_C PF05064.13 OWF41001.1 - 4.1 7.3 25.2 0.13 12.1 2.1 4.1 4 0 0 4 4 4 0 Nsp1-like C-terminal region Phasin PF05597.11 OWF41001.1 - 5.6 7.0 20.0 0.074 13.1 3.2 4.0 2 2 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Filament PF00038.21 OWF41001.1 - 8.4 5.9 35.2 0.081 12.5 11.2 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF1043 PF06295.12 OWF41001.1 - 9.6 6.2 22.1 2.8 8.0 4.2 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF1043) Mito_carr PF00153.27 OWF41002.1 - 2.8e-64 213.1 0.9 1.1e-21 76.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein fn3 PF00041.21 OWF41003.1 - 0.00024 21.4 0.0 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain DUF2369 PF10179.9 OWF41003.1 - 0.0076 16.6 0.0 0.031 14.7 0.0 2.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2369) Ig_3 PF13927.6 OWF41004.1 - 3.1e-11 43.7 1.1 4.9e-08 33.5 0.4 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 OWF41004.1 - 8.1e-08 32.2 0.3 0.0012 18.9 0.0 3.8 3 2 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF41004.1 - 1.4e-05 25.3 1.0 1.4e-05 25.3 1.0 2.8 3 1 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 OWF41004.1 - 0.00024 21.2 1.1 0.00078 19.6 0.3 2.3 2 0 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 OWF41004.1 - 0.0075 16.6 0.2 0.022 15.1 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III domain DUF4998 PF16389.5 OWF41004.1 - 0.08 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function PTN_MK_N PF05196.13 OWF41005.1 - 0.015 15.5 48.2 34 4.7 0.7 7.9 1 1 2 3 3 3 0 PTN/MK heparin-binding protein family, N-terminal domain DUF4236 PF14020.6 OWF41006.1 - 0.00015 22.3 0.0 40 4.9 0.0 5.1 2 1 2 5 5 5 0 Protein of unknown function (DUF4236) CS PF04969.16 OWF41006.1 - 0.00055 20.9 0.0 86 4.3 0.0 4.9 2 1 2 4 4 4 0 CS domain Fungal_KA1 PF16797.5 OWF41006.1 - 0.0054 16.4 0.7 43 3.8 0.0 4.6 2 1 2 4 4 4 0 Fungal kinase associated-1 domain Cu_amine_oxidN1 PF07833.11 OWF41006.1 - 0.22 12.0 0.0 89 3.7 0.0 3.4 2 1 1 3 3 3 0 Copper amine oxidase N-terminal domain PTN_MK_N PF05196.13 OWF41006.1 - 0.86 9.9 52.0 3.6 7.9 1.9 8.4 1 1 5 6 6 6 0 PTN/MK heparin-binding protein family, N-terminal domain DUF366 PF04017.12 OWF41007.1 - 0.043 13.3 0.2 0.18 11.3 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF366) Peptidase_U4 PF03419.13 OWF41007.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA RRM_5 PF13893.6 OWF41008.1 - 1.6e-05 24.5 0.0 2.9 7.5 0.0 7.0 7 2 2 9 9 9 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4033 PF13225.6 OWF41008.1 - 6.9e-05 22.8 0.0 39 4.3 0.0 7.5 7 2 0 8 8 8 1 Domain of unknown function (DUF4033) UPF1_Zn_bind PF09416.10 OWF41008.1 - 0.0064 16.5 0.2 2 8.3 0.0 4.7 4 1 0 4 4 4 1 RNA helicase (UPF2 interacting domain) GAF_3 PF13492.6 OWF41009.1 - 0.01 16.2 5.1 0.24 11.7 0.1 3.6 1 1 3 4 4 4 1 GAF domain Calpain_III PF01067.22 OWF41009.1 - 0.24 11.7 0.4 3.8 7.8 0.2 2.5 1 1 1 2 2 2 0 Calpain large subunit, domain III PhzC-PhzF PF02567.16 OWF41009.1 - 1.5 8.2 5.9 2.3 7.6 0.2 2.9 1 1 1 3 3 3 0 Phenazine biosynthesis-like protein Roc PF08477.13 OWF41010.1 - 3.8e-09 36.8 0.1 0.00038 20.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF41010.1 - 7.9e-09 35.6 0.1 1.8e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Death PF00531.22 OWF41010.1 - 9.2e-07 28.9 0.3 0.017 15.3 0.1 2.6 2 0 0 2 2 2 2 Death domain Ras PF00071.22 OWF41010.1 - 6.2e-06 25.9 0.1 0.013 15.1 0.0 2.5 2 0 0 2 2 2 2 Ras family Ank_2 PF12796.7 OWF41010.1 - 1.9e-05 25.2 0.0 4.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF41010.1 - 0.00012 22.2 0.0 0.21 12.2 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OWF41010.1 - 0.00038 21.0 0.0 0.009 16.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1891 PF09004.10 OWF41010.1 - 0.0045 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) MMR_HSR1 PF01926.23 OWF41010.1 - 0.0071 16.4 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ank_5 PF13857.6 OWF41010.1 - 0.011 16.0 0.0 0.043 14.1 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 OWF41010.1 - 0.031 14.7 0.0 0.24 11.9 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat ABC_tran PF00005.27 OWF41010.1 - 0.035 14.6 0.0 0.086 13.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OWF41010.1 - 0.046 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OWF41010.1 - 0.062 12.5 0.0 0.94 8.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 OWF41010.1 - 0.068 13.1 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 OWF41010.1 - 0.068 13.7 0.1 0.31 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF41010.1 - 0.082 12.8 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 OWF41010.1 - 0.099 12.5 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 OWF41010.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OWF41010.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 OWF41010.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 OWF41010.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_14 PF13173.6 OWF41010.1 - 0.16 12.0 0.1 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain rve PF00665.26 OWF41011.1 - 0.00092 19.4 0.1 0.05 13.8 0.0 2.8 2 1 0 2 2 2 1 Integrase core domain HTH_12 PF08461.10 OWF41011.1 - 0.012 15.5 0.2 0.27 11.2 0.2 2.4 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain NTP_transf_5 PF14907.6 OWF41011.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Oleosin PF01277.17 OWF41012.1 - 0.0023 17.6 0.3 0.0036 17.1 0.3 1.2 1 0 0 1 1 1 1 Oleosin Ribosomal_L19e PF01280.20 OWF41013.1 - 2e-65 219.2 12.9 2e-65 219.2 12.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e DUF1682 PF07946.14 OWF41013.1 - 7 5.8 14.9 8.9 5.4 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PFK PF00365.20 OWF41014.1 - 3.8e-197 653.2 4.6 1.5e-105 352.6 1.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase BAG PF02179.16 OWF41015.1 - 6.1e-18 65.0 0.7 9.9e-18 64.4 0.7 1.3 1 0 0 1 1 1 1 BAG domain WW PF00397.26 OWF41015.1 - 1.9e-11 43.8 0.2 3.9e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 WW domain T4_deiodinase PF00837.17 OWF41016.1 - 2.2e-35 122.1 0.1 2.4e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase zf-met PF12874.7 OWF41017.1 - 2e-24 85.2 17.6 8.5e-07 29.2 0.6 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF41017.1 - 3.8e-17 62.1 12.7 5.1e-06 26.6 0.7 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 OWF41017.1 - 7.2e-10 38.8 10.6 0.0012 18.9 0.1 4.3 4 0 0 4 4 4 3 DBF zinc finger zf-U1 PF06220.12 OWF41017.1 - 1.8e-07 30.8 8.3 0.0036 17.0 0.3 3.4 3 0 0 3 3 3 3 U1 zinc finger zf-C2H2_4 PF13894.6 OWF41017.1 - 0.00012 22.6 9.2 7.4 7.7 0.0 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_3 PF13878.6 OWF41017.1 - 0.0023 17.7 6.2 5.5 6.9 0.1 4.2 4 0 0 4 4 4 1 zinc-finger of acetyl-transferase ESCO zf-C2H2 PF00096.26 OWF41017.1 - 0.018 15.5 11.2 1.9 9.1 0.1 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OWF41017.1 - 0.023 15.0 16.9 2 8.8 0.1 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF3449 PF11931.8 OWF41017.1 - 0.026 14.3 1.2 6.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Mito_fiss_reg PF05308.11 OWF41017.1 - 0.21 11.6 3.8 0.38 10.8 3.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator GluR_Homer-bdg PF10606.9 OWF41017.1 - 1.2 9.4 9.1 5.4 7.3 0.2 3.3 3 0 0 3 3 3 0 Homer-binding domain of metabotropic glutamate receptor zf-HYPF PF07503.12 OWF41017.1 - 2.1 8.2 0.0 2.1 8.2 0.0 3.3 4 0 0 4 4 4 0 HypF finger zf-RRPl_C4 PF17026.5 OWF41017.1 - 2.9 8.0 10.1 5.1 7.3 5.4 2.7 2 1 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_aberr PF17017.5 OWF41017.1 - 3 8.0 8.8 2 8.5 1.5 2.8 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 OWF41017.1 - 3.2 7.6 11.9 15 5.4 0.1 4.1 4 1 0 4 4 4 0 zinc-finger C2H2-type DUF678 PF05077.12 OWF41017.1 - 3.7 7.8 9.6 15 5.8 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF678) zf-C2H2_9 PF16293.5 OWF41017.1 - 4.9 7.1 6.0 34 4.4 0.0 3.7 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-Sec23_Sec24 PF04810.15 OWF41017.1 - 6.2 7.0 8.6 35 4.6 0.1 4.0 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger VIR_N PF15912.5 OWF41017.1 - 7.2 6.1 8.6 0.39 10.3 3.4 1.7 2 1 0 2 2 2 0 Virilizer, N-terminal DUF1454 PF07305.12 OWF41018.1 - 0.062 12.7 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) DpnD-PcfM PF14207.6 OWF41018.1 - 0.066 13.1 0.3 8.3 6.4 0.0 2.7 1 1 0 2 2 2 0 DpnD/PcfM-like protein Bax1-I PF01027.20 OWF41019.1 - 1.9e-44 152.0 13.3 2.8e-44 151.5 13.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FMN_dh PF01070.18 OWF41019.1 - 0.028 13.4 0.3 0.051 12.6 0.3 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase CD20 PF04103.15 OWF41019.1 - 1.1 9.4 9.3 3.1 7.9 2.4 2.6 2 0 0 2 2 2 0 CD20-like family Cupin_8 PF13621.6 OWF41020.1 - 3.3e-08 33.5 0.1 5e-07 29.7 0.0 2.0 1 1 1 2 2 2 2 Cupin-like domain Peptidase_S24 PF00717.23 OWF41020.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase S24-like ANAPC4_WD40 PF12894.7 OWF41021.1 - 1.3e-10 41.4 0.1 0.0001 22.5 0.0 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OWF41021.1 - 1.5e-06 27.6 7.1 0.098 11.7 0.4 4.0 4 0 0 4 4 4 3 Coatomer WD associated region Clathrin PF00637.20 OWF41021.1 - 1.1e-05 25.3 9.4 1.1 9.1 0.0 6.2 4 1 2 6 6 6 3 Region in Clathrin and VPS PPR_2 PF13041.6 OWF41021.1 - 0.00069 19.8 1.6 0.6 10.3 0.0 5.0 4 0 0 4 4 4 1 PPR repeat family TPR_7 PF13176.6 OWF41021.1 - 0.00084 19.2 16.1 62 4.0 0.0 10.0 10 1 1 11 11 11 0 Tetratricopeptide repeat WD40 PF00400.32 OWF41021.1 - 0.004 18.0 7.4 23 6.1 0.1 6.3 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_1 PF00515.28 OWF41021.1 - 0.0043 16.8 24.2 0.65 9.9 1.5 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF2524 PF10732.9 OWF41021.1 - 0.023 15.0 0.1 0.1 12.9 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) PPR PF01535.20 OWF41021.1 - 0.051 13.8 14.1 1.6 9.1 0.1 6.8 6 1 2 8 8 8 0 PPR repeat TPR_2 PF07719.17 OWF41021.1 - 0.13 12.5 34.8 0.45 10.7 1.5 9.2 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF41021.1 - 0.25 11.7 20.1 10 6.5 0.1 7.8 5 2 2 8 8 8 0 Tetratricopeptide repeat PPR_1 PF12854.7 OWF41021.1 - 0.65 9.8 3.2 5.3 6.8 0.3 3.6 4 0 0 4 4 4 0 PPR repeat TPR_14 PF13428.6 OWF41021.1 - 0.87 10.6 18.6 3.4 8.8 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF41021.1 - 4.3 7.9 13.0 26 5.4 0.0 6.1 8 1 0 8 8 7 0 Tetratricopeptide repeat Trypsin PF00089.26 OWF41022.1 - 1.6e-72 243.9 7.7 1.9e-72 243.6 7.7 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF41022.1 - 2.8e-08 34.8 1.6 5.8e-08 33.8 1.6 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF41022.1 - 4.2e-06 27.1 0.3 6.4e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 OWF41022.1 - 0.00043 19.9 0.8 0.014 15.0 0.0 2.6 1 1 1 2 2 2 1 Chymotrypsin family Peptidase-S1 MFS_1 PF07690.16 OWF41023.1 - 4.8e-28 98.1 54.7 9.9e-16 57.6 24.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 OWF41023.1 - 1.6e-17 63.2 25.2 1.8e-10 40.0 18.6 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 OWF41023.1 - 2e-11 43.4 3.5 9.2e-06 24.8 0.0 3.1 1 1 1 2 2 2 2 MFS_1 like family PUCC PF03209.15 OWF41023.1 - 1.9e-10 40.4 19.7 3.7e-07 29.5 14.6 3.3 2 1 0 2 2 2 2 PUCC protein MFS_3 PF05977.13 OWF41023.1 - 6.9e-07 28.0 5.7 6.9e-07 28.0 5.7 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector LptF_LptG PF03739.14 OWF41023.1 - 5.6 5.7 10.6 0.63 8.8 0.4 2.5 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG LAP1C PF05609.12 OWF41025.1 - 0.94 8.5 5.6 1.1 8.3 5.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 OWF41026.1 - 3.6e-74 250.0 15.9 3.6e-74 250.0 15.9 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter DUF2631 PF10939.8 OWF41026.1 - 0.15 11.9 5.1 1.2 9.0 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2631) Ribosomal_L14 PF00238.19 OWF41027.1 - 8.2e-36 122.8 1.3 1e-35 122.5 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e T7SS_ESX1_EccB PF05108.13 OWF41027.1 - 0.062 11.9 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B ODR4-like PF14778.6 OWF41028.1 - 2.5e-95 319.6 0.1 3.2e-95 319.2 0.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like DUF2951 PF11166.8 OWF41028.1 - 0.085 13.1 0.9 0.18 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Hep_59 PF07052.11 OWF41028.1 - 0.42 11.4 4.9 3 8.6 0.0 2.7 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 Ank_2 PF12796.7 OWF41029.1 - 3.4e-61 203.8 11.8 2.6e-13 50.3 0.1 8.7 6 3 3 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF41029.1 - 4.1e-50 161.9 10.9 4.4e-05 23.6 0.0 12.9 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 OWF41029.1 - 3e-49 164.4 16.5 9.3e-07 29.0 0.1 11.9 10 2 2 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 OWF41029.1 - 5.2e-48 159.5 19.1 3.2e-05 24.2 0.1 13.6 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.6 OWF41029.1 - 1.9e-45 152.6 16.2 3.1e-08 34.0 0.0 10.4 8 3 3 11 11 11 10 Ankyrin repeats (many copies) AMP-binding PF00501.28 OWF41030.1 - 4.5e-60 203.4 0.0 5.4e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF41030.1 - 1.7e-08 35.3 0.0 3.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VWA PF00092.28 OWF41031.1 - 4.7e-43 147.4 1.9 5.6e-43 147.2 1.9 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF41031.1 - 2.1e-19 70.1 0.1 3.1e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF41031.1 - 6.9e-07 29.3 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF41031.1 - 9.2e-05 21.9 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Copine PF07002.16 OWF41031.1 - 0.059 12.8 0.2 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Copine CCDC14 PF15254.6 OWF41032.1 - 2.7e-42 145.5 40.6 1.5e-39 136.4 22.3 3.0 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 14 DUF4200 PF13863.6 OWF41032.1 - 0.16 12.3 26.2 0.14 12.6 9.6 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 OWF41032.1 - 0.18 11.8 30.1 1.1 9.3 17.4 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WD-3 PF09765.9 OWF41032.1 - 0.43 9.9 9.3 0.75 9.1 9.3 1.3 1 0 0 1 1 1 0 WD-repeat region LicD PF04991.13 OWF41032.1 - 0.57 10.3 7.2 0.31 11.1 2.7 2.4 2 0 0 2 2 2 0 LicD family Death PF00531.22 OWF41034.1 - 6.5e-06 26.2 1.1 2.8e-05 24.2 0.0 2.7 2 1 1 3 3 3 1 Death domain CRISPR_Cas2 PF09827.9 OWF41034.1 - 0.046 13.9 0.2 17 5.7 0.1 3.4 2 0 0 2 2 2 0 CRISPR associated protein Cas2 Baculo_PEP_C PF04513.12 OWF41034.1 - 0.12 12.4 3.4 4.6 7.3 0.1 3.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 OWF41034.1 - 0.19 12.3 35.5 0.2 12.2 13.2 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region LMBR1 PF04791.16 OWF41034.1 - 2.6 6.8 6.1 4.6 6.0 6.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Lipase_GDSL_2 PF13472.6 OWF41035.1 - 7.4e-07 29.7 0.0 7.7e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF41035.1 - 0.0047 16.9 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 OWF41035.1 - 0.046 13.0 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 OSK domain LTXXQ PF07813.12 OWF41037.1 - 0.048 14.4 0.3 0.079 13.7 0.3 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein PPV_E1_N PF00524.18 OWF41038.1 - 0.44 11.0 3.8 0.26 11.7 0.2 2.5 2 0 0 2 2 2 0 E1 Protein, N terminal domain DTC PF18102.1 OWF41039.1 - 8.9e-58 194.2 0.0 1.7e-57 193.2 0.0 1.5 2 0 0 2 2 1 1 Deltex C-terminal domain zf-C3HC4_2 PF13923.6 OWF41039.1 - 2.4e-09 36.9 10.9 3.8e-09 36.2 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF41039.1 - 4.2e-09 36.6 9.6 6.8e-09 35.9 9.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF41039.1 - 2.3e-08 33.7 5.9 3.3e-08 33.2 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41039.1 - 8e-08 32.2 4.6 8e-08 32.2 4.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF41039.1 - 8.1e-08 32.1 9.1 1.2e-07 31.5 9.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF41039.1 - 3.9e-07 29.8 11.5 6.3e-07 29.2 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41039.1 - 0.00012 21.8 7.5 0.00021 21.1 7.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF41039.1 - 0.00014 21.5 6.4 0.00014 21.5 6.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OWF41039.1 - 0.00032 20.9 8.6 0.001 19.3 8.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF41039.1 - 0.001 19.2 4.6 0.0017 18.4 4.6 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 OWF41039.1 - 0.0025 17.7 4.4 0.0051 16.7 4.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Siva PF05458.12 OWF41039.1 - 0.0041 16.8 2.2 0.0064 16.2 2.2 1.2 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Baculo_IE-1 PF05290.11 OWF41039.1 - 0.0096 15.9 4.3 0.015 15.2 4.3 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 OWF41039.1 - 0.028 14.6 9.0 0.093 12.9 9.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2_3rep PF18868.1 OWF41039.1 - 0.08 13.6 0.7 0.13 12.9 0.7 1.3 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF1272 PF06906.11 OWF41039.1 - 0.12 12.5 7.2 0.22 11.6 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 OWF41039.1 - 0.5 10.2 7.4 0.88 9.4 7.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 OWF41039.1 - 0.51 10.3 7.4 1.8 8.5 7.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 OWF41039.1 - 1.1 9.3 7.7 9.6 6.3 7.5 2.3 2 1 1 3 3 2 0 zinc-ribbons RecR PF02132.15 OWF41039.1 - 5.1 6.7 8.0 3 7.5 0.5 2.4 2 0 0 2 2 2 0 RecR protein Prok-RING_1 PF14446.6 OWF41039.1 - 5.9 6.9 10.0 1e+03 -0.3 10.0 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Rhodanese PF00581.20 OWF41040.1 - 1.3e-09 38.6 0.0 2.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 OWF41041.1 - 8.2e-09 36.0 0.1 1.7e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DsrD PF08679.11 OWF41041.1 - 0.021 15.1 0.0 0.07 13.4 0.0 1.9 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Hexokinase_2 PF03727.16 OWF41042.1 - 8.2e-84 280.8 0.0 1.1e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OWF41042.1 - 1.7e-67 227.2 0.0 2.3e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FYVE PF01363.21 OWF41043.1 - 2.8e-11 43.4 12.9 5.1e-11 42.5 12.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OWF41043.1 - 1.2e-05 25.5 9.1 4.5e-05 23.7 9.1 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger Pex24p PF06398.11 OWF41043.1 - 0.0013 17.9 0.3 0.0016 17.5 0.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 OWF41043.1 - 0.27 10.6 2.0 0.43 10.0 2.0 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF639) zf-RING_5 PF14634.6 OWF41043.1 - 0.58 10.2 12.6 1.5 8.9 8.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Zf_RING PF16744.5 OWF41043.1 - 0.81 9.8 8.4 1.6 8.9 8.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger SdpI PF13630.6 OWF41043.1 - 6.5 7.0 7.0 0.66 10.2 1.7 1.9 2 0 0 2 2 2 0 SdpI/YhfL protein family Tweety PF04906.13 OWF41043.1 - 9.3 4.8 10.7 7.3 5.1 0.5 2.2 2 0 0 2 2 2 0 Tweety Cullin PF00888.22 OWF41044.1 - 6.4e-14 51.5 0.7 7.5e-14 51.3 0.7 1.1 1 0 0 1 1 1 1 Cullin family DUF4248 PF14053.6 OWF41044.1 - 0.0065 16.5 0.8 5.2 7.2 0.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4248) DASH_Dad1 PF08649.10 OWF41044.1 - 0.056 13.6 0.2 1.2 9.4 0.3 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad1 Secretin_N_2 PF07655.13 OWF41044.1 - 0.11 13.1 0.0 0.7 10.5 0.0 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain Lectin_C PF00059.21 OWF41045.1 - 4.9e-63 210.6 22.1 3e-18 66.5 1.3 4.2 4 0 0 4 4 4 4 Lectin C-type domain UL45 PF05473.12 OWF41045.1 - 4e-06 26.6 12.2 0.026 14.2 0.1 4.8 2 2 2 4 4 4 2 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 OWF41045.1 - 2.8 8.4 8.8 8.2 6.9 0.9 4.0 4 1 0 4 4 4 0 Extracellular link domain TPMT PF05724.11 OWF41046.1 - 3e-46 157.8 0.0 3.6e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OWF41046.1 - 0.031 15.0 0.0 0.58 10.9 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 OWF41047.1 - 6.1e-46 156.8 0.0 7.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PWWP PF00855.17 OWF41048.1 - 1.8e-13 50.7 1.6 7.7e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 PWWP domain MLTD_N PF06474.12 OWF41048.1 - 0.15 12.3 0.8 1.4 9.2 0.2 2.7 2 0 0 2 2 2 0 MltD lipid attachment motif TPR_1 PF00515.28 OWF41049.1 - 2.3e-18 65.2 3.0 5e-07 29.3 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF41049.1 - 4.2e-15 54.6 1.6 0.00011 22.1 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF41049.1 - 4.7e-08 32.6 0.2 0.0069 16.1 0.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 OWF41049.1 - 8.2e-07 28.8 1.7 0.0026 17.8 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OWF41049.1 - 5.8e-05 22.5 0.1 0.0053 16.0 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF41049.1 - 0.00012 22.2 2.0 0.0012 18.9 1.6 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF41049.1 - 0.00017 21.8 0.8 0.013 15.8 0.4 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF41049.1 - 0.00031 21.3 0.9 0.07 14.0 1.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF41049.1 - 0.00074 20.0 0.2 0.082 13.4 1.4 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF41049.1 - 0.0011 18.8 0.3 3 8.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF41049.1 - 0.0039 17.7 0.0 0.09 13.4 0.1 3.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF41049.1 - 0.11 12.9 0.6 73 4.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 OWF41049.1 - 2.6 7.7 8.7 0.22 11.2 2.9 2.0 2 1 0 2 2 2 0 26S proteasome subunit RPN7 DJ-1_PfpI PF01965.24 OWF41050.1 - 2.5e-06 27.4 0.1 1.2e-05 25.2 0.1 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 OWF41050.1 - 0.02 14.5 0.1 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain found in long catalases CLAMP PF14769.6 OWF41051.1 - 1.9e-22 79.5 0.5 3.9e-22 78.6 0.5 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 FERM_C PF09380.10 OWF41051.1 - 0.13 12.6 0.6 15 6.1 0.0 2.2 2 0 0 2 2 2 0 FERM C-terminal PH-like domain DUF229 PF02995.17 OWF41052.1 - 1.2e-121 406.8 1.5 4.2e-121 405.0 1.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF41052.1 - 6.8e-10 38.8 0.3 2.5e-09 37.0 0.3 1.8 1 1 0 1 1 1 1 Sulfatase DUF3153 PF11353.8 OWF41052.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3153) TCR PF03638.15 OWF41052.1 - 5.8 7.3 6.0 27 5.2 0.8 2.4 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain AA_permease PF00324.21 OWF41053.1 - 2.5e-80 270.4 37.2 3.1e-80 270.1 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OWF41053.1 - 1.2e-14 54.2 0.1 1.9e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Solute carrier family 12 Atg8 PF02991.16 OWF41054.1 - 1.1e-48 163.7 0.1 1.3e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OWF41054.1 - 4.2e-07 30.3 0.0 5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PAF PF15715.5 OWF41056.1 - 8.2e-32 110.6 5.1 9e-32 110.5 5.1 1.0 1 0 0 1 1 1 1 PCNA-associated factor histone like domain 7tm_1 PF00001.21 OWF41058.1 - 7.3e-09 35.3 13.4 9.1e-09 35.0 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FixH PF05751.11 OWF41058.1 - 0.096 12.7 0.4 0.24 11.4 0.4 1.7 1 0 0 1 1 1 0 FixH Phage_holin_5_2 PF16079.5 OWF41058.1 - 0.15 12.4 1.7 1 9.8 0.5 2.6 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF2542 PF10808.8 OWF41058.1 - 10 6.7 8.2 12 6.5 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) RPE65 PF03055.15 OWF41059.1 - 4e-76 257.1 0.1 4.7e-76 256.8 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein NIT PF08376.10 OWF41060.1 - 3.1e-25 90.0 0.0 4.2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing Guanylate_cyc PF00211.20 OWF41060.1 - 6.8e-08 32.3 1.1 2.1e-07 30.7 0.9 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OWF41060.1 - 0.00023 20.7 1.0 0.00056 19.4 0.0 2.0 2 0 0 2 2 2 1 Heme NO binding associated AgrB PF04647.15 OWF41060.1 - 0.13 11.6 4.3 2 7.7 0.5 2.6 3 0 0 3 3 3 0 Accessory gene regulator B CG-1 PF03859.16 OWF41061.1 - 6e-43 145.3 1.5 6e-43 145.3 1.5 2.1 2 0 0 2 2 2 1 CG-1 domain TIG PF01833.24 OWF41061.1 - 1.9e-08 34.3 0.5 1.4e-07 31.5 0.1 2.9 3 0 0 3 3 3 1 IPT/TIG domain Ank_2 PF12796.7 OWF41061.1 - 2.4e-08 34.5 0.2 2.1e-07 31.4 0.2 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) IQ PF00612.27 OWF41061.1 - 3.6e-07 29.4 28.0 0.04 13.7 1.4 6.0 6 0 0 6 6 6 4 IQ calmodulin-binding motif Ank_5 PF13857.6 OWF41061.1 - 1e-05 25.7 1.7 0.00054 20.2 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF41061.1 - 0.00013 22.5 0.4 0.013 16.0 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41061.1 - 0.011 16.2 0.5 13 6.7 0.0 3.4 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 OWF41061.1 - 0.2 12.2 5.7 11 6.7 0.1 3.5 4 0 0 4 4 4 0 Ankyrin repeat DUF3395 PF11875.8 OWF41062.1 - 1.2e-43 148.7 0.2 1.2e-43 148.7 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 OWF41062.1 - 1e-18 67.2 2.4 2.2e-18 66.1 2.4 1.6 1 0 0 1 1 1 1 DnaJ domain Csm1_N PF18504.1 OWF41063.1 - 0.014 15.7 2.7 0.014 15.7 2.7 14.8 12 5 6 19 19 19 0 Csm1 N-terminal domain DUF3800 PF12686.7 OWF41063.1 - 0.13 12.9 3.4 61 4.3 3.0 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DJ-1_PfpI PF01965.24 OWF41064.1 - 3e-50 170.2 0.7 3.4e-50 170.1 0.7 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 OWF41064.1 - 0.051 13.2 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 OWF41064.1 - 0.088 12.5 0.0 0.35 10.5 0.0 1.8 1 1 1 2 2 2 0 ThiJ/PfpI family-like CofC PF01983.16 OWF41064.1 - 0.13 11.4 0.0 1.5 7.9 0.0 2.0 1 1 1 2 2 2 0 Guanylyl transferase CofC like Mito_carr PF00153.27 OWF41065.1 - 4.8e-61 202.7 5.0 5e-21 74.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3BGR PF04908.15 OWF41066.1 - 2.8e-18 65.9 0.0 3.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 OWF41066.1 - 5.8e-05 23.2 0.0 9.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Lectin_C PF00059.21 OWF41067.1 - 1e-31 109.9 2.8 1.6e-17 64.2 0.2 2.3 2 0 0 2 2 2 2 Lectin C-type domain DUF347 PF03988.12 OWF41067.1 - 0.0048 17.1 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Podoplanin PF05808.11 OWF41067.1 - 0.19 11.8 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Podoplanin Lectin_C PF00059.21 OWF41068.1 - 4.7e-38 130.2 17.0 5.5e-20 72.1 2.3 2.9 3 0 0 3 3 3 2 Lectin C-type domain Chordopox_A33R PF05966.12 OWF41068.1 - 0.0027 17.0 0.8 0.061 12.6 0.1 2.4 2 0 0 2 2 2 1 Chordopoxvirus A33R protein His_kinase PF06580.13 OWF41068.1 - 0.008 16.5 0.0 7.6 6.9 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase Med3 PF11593.8 OWF41068.1 - 3.7 6.6 19.3 5 6.2 19.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NUDE_C PF04880.13 OWF41068.1 - 6.1 7.3 7.6 8.5 6.8 7.6 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region CD34_antigen PF06365.12 OWF41069.1 - 0.051 13.2 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family PRCC PF10253.9 OWF41069.1 - 2 9.2 6.1 2.7 8.7 6.1 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PWWP PF00855.17 OWF41070.1 - 5.4e-14 52.4 0.2 5.4e-14 52.4 0.2 4.7 5 2 1 6 6 6 1 PWWP domain zf-CW PF07496.15 OWF41070.1 - 8.2e-11 41.8 8.7 2.2e-10 40.4 8.7 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger PucR PF07905.11 OWF41070.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Bin3 PF06859.12 OWF41071.1 - 3.8e-41 140.1 0.0 3.8e-41 140.1 0.0 1.9 2 0 0 2 2 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 OWF41071.1 - 1.3e-11 45.0 0.0 9.9e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OWF41071.1 - 3.4e-11 43.8 0.0 1.2e-09 38.7 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF41071.1 - 8.1e-11 41.9 0.0 1.6e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OWF41071.1 - 1.4e-10 41.7 0.0 1e-08 35.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF41071.1 - 6.6e-09 35.8 0.0 3.5e-08 33.5 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 OWF41071.1 - 7.7e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF41071.1 - 0.00032 20.3 0.0 0.0029 17.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OWF41071.1 - 0.0016 17.9 0.3 0.005 16.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 OWF41071.1 - 0.0024 17.3 0.0 0.0082 15.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OWF41071.1 - 0.0044 16.4 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OWF41071.1 - 0.0054 16.5 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OWF41071.1 - 0.011 15.7 0.2 0.083 12.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 OWF41071.1 - 0.1 12.1 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 Lectin_C PF00059.21 OWF41072.1 - 6.5e-16 59.0 0.1 9.4e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Kinesin PF00225.23 OWF41073.1 - 1.3e-113 379.3 0.1 2.6e-113 378.3 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 OWF41073.1 - 1.3e-56 191.6 2.7 6.4e-49 166.5 0.2 4.5 5 0 0 5 5 5 2 Kinesin-associated DUF3694 PF12473.8 OWF41073.1 - 1.7e-40 139.2 0.0 1.7e-40 139.2 0.0 2.8 3 0 0 3 3 3 1 Kinesin protein Microtub_bd PF16796.5 OWF41073.1 - 1.8e-22 79.9 0.0 9.2e-22 77.6 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 OWF41073.1 - 4.5e-13 49.4 9.2 4.6e-11 43.0 0.2 3.5 3 0 0 3 3 3 2 Kinesin protein 1B PH PF00169.29 OWF41073.1 - 6.4e-10 39.5 0.8 4.5e-09 36.7 0.1 2.9 3 0 0 3 3 3 1 PH domain FHA PF00498.26 OWF41073.1 - 1e-06 29.0 0.0 6.8e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OWF41073.1 - 7.6e-05 23.0 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain E1-E2_ATPase PF00122.20 OWF41074.1 - 1.7e-39 135.2 0.0 8.3e-39 133.0 0.0 2.2 1 1 1 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 OWF41074.1 - 1.3e-26 93.1 1.1 3.8e-26 91.6 1.1 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 OWF41074.1 - 7.4e-16 59.1 0.1 3.8e-05 24.1 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OWF41074.1 - 3.5e-05 23.4 0.0 8.6e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OWF41074.1 - 9e-05 22.5 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OWF41075.1 - 3.8e-38 130.8 0.4 3.8e-38 130.8 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 OWF41075.1 - 2.4e-22 79.3 0.8 6.8e-22 77.9 0.8 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 OWF41075.1 - 8.8e-19 68.6 0.2 9.8e-12 45.6 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OWF41075.1 - 1.3e-08 34.4 0.0 2.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OWF41075.1 - 1.9e-05 24.6 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 OWF41075.1 - 0.0021 17.8 4.6 0.0021 17.8 4.6 2.7 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 OWF41075.1 - 0.016 14.9 2.1 0.4 10.4 0.0 2.7 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Ost5 PF05251.12 OWF41075.1 - 0.37 11.1 0.1 0.37 11.1 0.1 3.1 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 COX4_pro PF03626.14 OWF41075.1 - 0.46 10.9 4.0 0.88 10.0 0.1 3.0 2 1 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Ion_trans PF00520.31 OWF41076.1 - 3.2e-13 49.5 23.3 5.6e-13 48.7 23.3 1.3 1 0 0 1 1 1 1 Ion transport protein TRPM_tetra PF16519.5 OWF41076.1 - 6.2e-12 45.4 2.3 1.5e-11 44.2 2.3 1.7 1 0 0 1 1 1 1 Tetramerisation domain of TRPM PKD_channel PF08016.12 OWF41076.1 - 0.0018 17.0 9.8 0.0022 16.8 4.4 2.3 1 1 1 2 2 2 2 Polycystin cation channel CD20 PF04103.15 OWF41076.1 - 0.089 12.9 1.9 0.1 12.7 0.3 2.0 2 0 0 2 2 2 0 CD20-like family Glyco_transf_7C PF02709.14 OWF41077.1 - 9e-21 73.3 0.2 1.9e-20 72.3 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 OWF41077.1 - 4.6e-17 61.9 1.7 7.7e-17 61.2 1.7 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 DUF4234 PF14018.6 OWF41077.1 - 0.047 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DEAD PF00270.29 OWF41078.1 - 2e-10 40.7 0.0 2.6e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fringe PF02434.16 OWF41079.1 - 5.3e-15 55.5 0.6 2.9e-14 53.1 0.6 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF41079.1 - 5.5e-09 36.1 0.1 0.00031 20.6 0.2 2.5 1 1 1 2 2 2 2 Galactosyltransferase RVT_1 PF00078.27 OWF41080.1 - 2.6e-19 69.6 0.2 6.7e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 OWF41081.1 - 4.8e-13 48.8 37.6 7.9e-06 26.0 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF41081.1 - 2.8e-12 46.5 27.7 0.00071 19.9 3.3 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF41081.1 - 1.6e-07 31.5 30.9 0.048 14.5 0.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF41081.1 - 0.064 13.6 0.4 0.064 13.6 0.4 4.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 OWF41081.1 - 0.071 13.0 1.3 0.99 9.4 0.2 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4144 PF13642.6 OWF41081.1 - 0.093 13.3 0.3 0.25 11.9 0.3 1.7 1 0 0 1 1 1 0 protein structure with unknown function zf-met PF12874.7 OWF41081.1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.8 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zinc-ribbons_6 PF07191.12 OWF41081.1 - 0.93 9.5 7.1 0.87 9.6 1.8 2.7 2 0 0 2 2 2 0 zinc-ribbons zf_C2H2_ZHX PF18387.1 OWF41081.1 - 1.4 8.7 16.7 0.17 11.6 0.4 3.5 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 OWF41081.1 - 2.7 8.7 16.8 0.16 12.6 2.6 3.2 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats MBOAT PF03062.19 OWF41082.1 - 5.8e-29 101.5 0.3 1.3e-28 100.4 0.3 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Rsa3 PF14615.6 OWF41083.1 - 0.00052 19.5 2.1 4.7 6.8 0.0 4.7 1 1 1 4 4 4 3 Ribosome-assembly protein 3 YonK PF09642.10 OWF41083.1 - 0.00061 19.9 0.1 12 6.2 0.0 4.2 3 2 2 5 5 5 3 YonK protein YonK PF09642.10 OWF41084.1 - 0.037 14.2 0.0 62 3.9 0.0 3.4 2 1 0 3 3 3 0 YonK protein Rsa3 PF14615.6 OWF41085.1 - 0.011 15.3 0.8 2.4 7.8 0.0 3.0 2 2 2 4 4 4 0 Ribosome-assembly protein 3 YonK PF09642.10 OWF41085.1 - 0.066 13.4 0.1 9 6.5 0.0 2.7 2 1 2 4 4 4 0 YonK protein MliC PF09864.9 OWF41085.1 - 0.51 10.3 4.4 22 5.1 4.3 2.8 1 1 1 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme PH PF00169.29 OWF41086.1 - 2.6e-12 47.1 6.4 1.3e-06 28.8 0.3 3.2 3 0 0 3 3 3 2 PH domain ELYS-bb PF16687.5 OWF41087.1 - 3.7e-83 279.8 2.5 2.2e-81 273.9 2.5 2.1 1 1 0 1 1 1 1 beta-propeller of ELYS nucleoporin ELYS PF13934.6 OWF41087.1 - 1.1e-51 175.9 1.5 1.1e-51 175.9 1.5 1.7 2 0 0 2 2 2 1 Nuclear pore complex assembly DUF3291 PF11695.8 OWF41087.1 - 0.14 11.8 0.0 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3291) Guanylate_cyc PF00211.20 OWF41088.1 - 3.4e-65 219.1 0.0 7e-65 218.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF41088.1 - 5e-28 98.1 0.0 5.8e-27 94.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 OWF41088.1 - 3.8e-24 85.5 0.0 7.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.25 OWF41088.1 - 3.2e-22 79.2 0.0 5.4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.6 OWF41088.1 - 4.3e-08 33.2 0.3 9.1e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein EGF_2 PF07974.13 OWF41088.1 - 3.8e-05 24.0 42.0 0.03 14.7 10.8 3.7 3 0 0 3 3 3 3 EGF-like domain HNOBA PF07701.14 OWF41088.1 - 0.0031 17.0 1.2 0.0051 16.3 1.2 1.3 1 0 0 1 1 1 1 Heme NO binding associated Syndecan PF01034.20 OWF41088.1 - 0.15 12.0 2.6 0.31 11.0 2.6 1.5 1 0 0 1 1 1 0 Syndecan domain CbiM PF01891.16 OWF41088.1 - 0.56 10.0 3.1 1.2 8.9 3.1 1.5 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Phytoreo_P8 PF07124.11 OWF41088.1 - 0.58 9.1 5.4 0.96 8.3 5.4 1.3 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 TPR_12 PF13424.6 OWF41090.1 - 1e-12 48.1 10.9 0.0015 18.7 0.2 4.1 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF41090.1 - 8.3e-10 38.1 4.1 0.34 11.2 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat zf-MYND PF01753.18 OWF41090.1 - 4.2e-09 36.3 7.2 8.4e-09 35.4 7.2 1.5 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 OWF41090.1 - 1.5e-08 34.1 2.9 0.32 11.2 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF41090.1 - 4.3e-08 32.6 3.5 0.12 12.3 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF41090.1 - 2e-06 27.4 2.9 2.5e-06 27.1 0.7 2.0 2 1 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 OWF41090.1 - 4.5e-05 23.2 5.6 0.67 9.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF41090.1 - 0.00073 19.4 7.3 0.37 10.9 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-Mss51 PF13824.6 OWF41090.1 - 0.031 14.4 3.7 0.1 12.7 3.7 1.9 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_6 PF13174.6 OWF41090.1 - 0.041 14.5 9.2 0.43 11.3 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat NIR_SIR_ferr PF03460.17 OWF41090.1 - 0.06 13.2 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain TPR_14 PF13428.6 OWF41090.1 - 0.085 13.7 6.9 39 5.4 0.1 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF41090.1 - 0.15 12.5 1.3 0.87 10.1 0.2 2.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF41090.1 - 0.59 10.8 8.5 38 5.0 3.2 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat TNFR_c6 PF00020.18 OWF41091.1 - 2.1e-07 31.2 36.4 0.00039 20.8 2.3 4.4 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region TMEM154 PF15102.6 OWF41091.1 - 9.3e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.8 OWF41091.1 - 0.00042 20.2 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4448 PF14610.6 OWF41091.1 - 0.01 15.7 0.6 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Chordopox_A13L PF05961.11 OWF41091.1 - 0.018 15.2 0.3 0.04 14.1 0.3 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TMEMspv1-c74-12 PF11044.8 OWF41091.1 - 0.019 14.9 0.7 0.034 14.1 0.7 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF5385 PF17359.2 OWF41091.1 - 0.022 14.3 0.3 0.05 13.2 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 OWF41091.1 - 0.022 15.6 0.0 0.061 14.2 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OWF41091.1 - 0.032 14.1 0.1 0.079 12.8 0.0 1.8 2 0 0 2 2 2 0 Rifin Death PF00531.22 OWF41091.1 - 0.041 14.0 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Death domain 7TM_GPCR_Srv PF10323.9 OWF41091.1 - 0.041 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv FAP PF07174.11 OWF41091.1 - 0.042 13.3 13.0 0.081 12.4 13.0 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4366 PF14283.6 OWF41091.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Baculo_11_kDa PF06143.11 OWF41091.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family PspB PF06667.12 OWF41091.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B EVI2A PF05399.11 OWF41091.1 - 0.19 11.3 4.3 0.12 12.0 1.3 1.9 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF1180 PF06679.12 OWF41091.1 - 0.66 10.4 0.0 0.66 10.4 0.0 2.4 1 1 1 2 2 1 0 Protein of unknown function (DUF1180) SKG6 PF08693.10 OWF41091.1 - 6.1 6.3 12.0 12 5.4 12.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 7tm_1 PF00001.21 OWF41092.1 - 1.2e-24 87.1 9.8 1.5e-24 86.7 9.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Chlorophyllase2 PF12740.7 OWF41093.1 - 2.7e-49 167.4 0.0 3.9e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OWF41093.1 - 1.8e-16 60.0 0.1 3.8e-15 55.7 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase DUF1749 PF08538.10 OWF41093.1 - 0.081 12.0 0.1 0.18 10.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) Fuseless PF15993.5 OWF41094.1 - 4e-60 203.5 16.7 4.8e-60 203.3 16.7 1.0 1 0 0 1 1 1 1 Fuseless PPR PF01535.20 OWF41094.1 - 0.069 13.4 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 PPR repeat HLH PF00010.26 OWF41095.1 - 3.1e-16 59.1 0.4 5.5e-16 58.3 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF41095.1 - 0.0018 18.4 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Hairy Orange Med26 PF08711.11 OWF41095.1 - 0.089 12.8 0.0 0.34 11.0 0.0 2.0 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Voltage_CLC PF00654.20 OWF41096.1 - 2.5e-92 309.8 18.4 2.5e-92 309.8 18.4 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 OWF41096.1 - 1.6e-07 31.6 0.3 0.0093 16.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain Tim17 PF02466.19 OWF41096.1 - 0.78 10.1 4.5 5.2 7.5 0.1 3.5 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family TBP PF00352.21 OWF41098.1 - 1e-14 54.2 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) LRR_8 PF13855.6 OWF41099.1 - 2.7e-56 187.2 108.8 7e-17 60.9 4.1 7.2 3 1 6 9 9 9 9 Leucine rich repeat 7tm_1 PF00001.21 OWF41099.1 - 3.4e-26 92.2 16.2 4.9e-26 91.6 16.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 OWF41099.1 - 2.1e-18 66.1 27.5 5.2e-09 36.2 0.8 9.1 4 3 10 14 14 14 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF41099.1 - 1.4e-17 63.8 0.9 1.1e-06 28.6 0.0 4.6 3 1 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) 7TM_GPCR_Srx PF10328.9 OWF41099.1 - 8.1e-07 28.9 20.1 1.5e-06 28.0 20.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF41099.1 - 7.9e-06 25.4 8.4 1.4e-05 24.6 8.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 OWF41099.1 - 7e-05 22.3 12.2 0.00037 19.9 12.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw LRR_1 PF00560.33 OWF41099.1 - 0.0059 17.0 63.3 1.3 9.9 0.1 12.6 13 1 1 14 14 14 4 Leucine Rich Repeat LRR_9 PF14580.6 OWF41099.1 - 0.02 14.4 17.5 0.089 12.3 2.2 3.9 1 1 2 4 4 4 0 Leucine-rich repeat Git3 PF11710.8 OWF41099.1 - 0.11 12.3 12.1 0.21 11.3 12.1 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 LRR_8 PF13855.6 OWF41100.1 - 1.8e-73 242.2 102.3 1.9e-15 56.3 5.8 7.3 2 1 6 8 8 8 8 Leucine rich repeat 7tm_1 PF00001.21 OWF41100.1 - 3.3e-26 92.2 17.0 5.3e-26 91.5 17.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 OWF41100.1 - 1.6e-23 82.4 69.4 3.3e-06 27.3 3.0 8.8 4 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF41100.1 - 6e-17 61.8 10.0 2.7e-07 30.6 0.1 4.6 2 1 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) 7TM_GPCR_Srx PF10328.9 OWF41100.1 - 6.8e-06 25.9 20.6 1.3e-05 25.0 20.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF41100.1 - 4.5e-05 22.9 9.4 7.5e-05 22.2 9.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv LRR_9 PF14580.6 OWF41100.1 - 5.4e-05 22.8 20.0 0.0002 20.9 3.0 3.7 1 1 2 4 4 4 2 Leucine-rich repeat 7TM_GPCR_Srw PF10324.9 OWF41100.1 - 0.001 18.4 11.6 0.0051 16.1 11.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Git3 PF11710.8 OWF41100.1 - 0.061 13.1 11.9 0.13 12.1 11.9 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 LRR_1 PF00560.33 OWF41100.1 - 2.4 9.0 53.3 3.5 8.5 0.3 12.1 13 0 0 13 13 13 0 Leucine Rich Repeat DUF4106 PF13388.6 OWF41101.1 - 3.4 6.8 16.0 14 4.8 6.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4106) PH PF00169.29 OWF41102.1 - 1.3e-13 51.4 1.7 1.3e-13 51.3 0.8 1.5 2 0 0 2 2 2 1 PH domain Mcp5_PH PF12814.7 OWF41102.1 - 8.4e-05 22.7 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 OWF41102.1 - 0.066 13.6 3.4 0.56 10.7 3.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain 7tm_1 PF00001.21 OWF41103.1 - 2.5e-05 23.7 10.4 4.1e-05 23.0 10.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Reeler PF02014.16 OWF41104.1 - 3.7e-16 60.1 0.0 5.6e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Reeler domain MFS_1 PF07690.16 OWF41105.1 - 2.8e-28 98.9 40.7 1.4e-27 96.6 20.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OWF41105.1 - 2.2e-14 53.6 2.9 2.2e-14 53.6 2.9 2.1 2 1 0 2 2 2 1 Nodulin-like TssO PF17561.2 OWF41105.1 - 5.1 7.2 0.0 5.1 7.2 0.0 3.3 3 0 0 3 3 3 0 Type VI secretion system, TssO zf-RING_9 PF13901.6 OWF41106.1 - 1.3e-63 214.7 17.3 1.3e-63 214.7 17.3 2.3 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon Zn_Tnp_IS91 PF14319.6 OWF41106.1 - 0.082 12.9 9.9 0.12 12.5 4.2 3.1 2 0 0 2 2 2 0 Transposase zinc-binding domain WD40 PF00400.32 OWF41107.1 - 3.7e-12 46.5 5.1 6.5e-05 23.6 0.0 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.6 OWF41107.1 - 3.2e-05 23.6 0.0 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 OWF41107.1 - 0.0022 18.4 0.2 12 6.6 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain ANAPC4_WD40 PF12894.7 OWF41107.1 - 0.0025 18.1 0.1 4.8 7.5 0.0 3.6 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TcfC PF16967.5 OWF41107.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 E-set like domain Macoilin PF09726.9 OWF41107.1 - 4.8 5.6 10.1 6.7 5.1 10.1 1.2 1 0 0 1 1 1 0 Macoilin family Lectin_C PF00059.21 OWF41108.1 - 2.2e-10 41.2 0.4 3.5e-10 40.6 0.4 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF41108.1 - 0.00033 20.4 0.2 0.00046 19.9 0.1 1.3 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF41109.1 - 2.9e-08 34.4 3.6 6e-08 33.4 3.6 1.6 1 1 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF41109.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF41110.1 - 4.4e-14 53.1 4.3 5.5e-14 52.8 4.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF41110.1 - 0.00011 21.9 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF41111.1 - 3.1e-14 53.6 4.4 3.9e-14 53.3 4.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF41111.1 - 4.1e-06 26.6 0.2 7.8e-06 25.7 0.2 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF41111.1 - 0.0095 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Lectin_C PF00059.21 OWF41112.1 - 7e-08 33.2 1.4 1.3e-07 32.4 1.1 1.6 1 1 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF41112.1 - 0.019 14.6 0.1 0.03 14.0 0.0 1.3 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like WD40 PF00400.32 OWF41113.1 - 3.4e-17 62.5 19.8 0.00019 22.2 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF41113.1 - 1.6e-06 28.3 1.8 0.69 10.3 0.1 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 OWF41113.1 - 0.097 13.0 0.7 1 9.7 0.1 2.7 2 1 0 2 2 2 0 FHA domain LRR_8 PF13855.6 OWF41115.1 - 1.9e-28 98.0 38.0 1e-13 50.8 8.0 8.7 6 4 2 8 8 8 6 Leucine rich repeat LRR_5 PF13306.6 OWF41115.1 - 1.1e-09 38.4 6.0 0.0011 18.9 0.1 3.8 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF41115.1 - 1.6e-09 37.8 48.3 0.0059 17.0 2.6 8.9 6 3 7 13 13 13 9 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF41115.1 - 2.8e-06 27.2 0.9 4.7e-06 26.5 0.9 1.3 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF41115.1 - 1.7e-05 24.7 28.3 1.6 9.6 0.3 11.1 13 0 0 13 13 13 1 Leucine Rich Repeat TIR_2 PF13676.6 OWF41115.1 - 0.0067 17.0 0.1 0.029 15.0 0.0 2.1 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 OWF41115.1 - 0.017 14.6 0.4 0.017 14.6 0.4 3.9 4 0 0 4 4 4 0 Leucine-rich repeat LRR_8 PF13855.6 OWF41116.1 - 1.2e-27 95.4 38.3 8.1e-13 47.9 8.4 8.9 7 2 1 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 OWF41116.1 - 1.6e-09 37.8 47.9 0.019 15.4 1.1 9.3 6 3 3 10 10 10 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF41116.1 - 4.9e-09 36.2 3.7 0.023 14.7 0.1 3.9 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) TIR PF01582.20 OWF41116.1 - 4.7e-07 29.8 0.8 7.7e-07 29.1 0.8 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF41116.1 - 0.0025 18.4 0.0 0.015 15.9 0.0 2.3 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 OWF41116.1 - 0.027 14.0 9.7 0.043 13.3 0.4 4.0 4 0 0 4 4 4 0 Leucine-rich repeat LRR_1 PF00560.33 OWF41116.1 - 0.042 14.4 33.9 13 6.8 1.8 11.3 11 2 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF41116.1 - 0.15 12.2 40.6 1.5 9.0 0.2 10.3 11 0 0 11 11 11 0 Leucine Rich repeat Homeodomain PF00046.29 OWF41117.1 - 9.5e-23 79.8 6.9 1.6e-22 79.1 6.9 1.4 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 OWF41117.1 - 4.5e-13 48.2 0.0 8.4e-13 47.3 0.0 1.4 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.11 OWF41117.1 - 0.0025 17.7 0.9 0.0065 16.3 0.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain CENP-B_N PF04218.13 OWF41117.1 - 0.035 13.7 0.3 0.079 12.6 0.3 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Snf7 PF03357.21 OWF41118.1 - 4.5e-53 179.4 12.0 5.3e-53 179.2 12.0 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 OWF41118.1 - 1.6e-05 25.2 2.9 0.00011 22.5 0.4 2.8 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OWF41118.1 - 0.0003 19.8 5.9 0.00041 19.3 5.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Glutaredoxin PF00462.24 OWF41118.1 - 0.019 15.2 1.0 0.12 12.6 0.2 2.5 1 1 1 2 2 2 0 Glutaredoxin CLZ PF16526.5 OWF41118.1 - 0.024 15.0 4.0 0.78 10.1 0.0 3.5 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SpoIISA_toxin PF14171.6 OWF41118.1 - 0.046 13.4 0.9 0.063 13.0 0.3 1.5 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system FliJ PF02050.16 OWF41118.1 - 0.11 12.8 10.7 0.068 13.4 3.0 2.7 1 1 2 3 3 3 0 Flagellar FliJ protein ZapB PF06005.12 OWF41118.1 - 0.2 12.1 0.3 0.2 12.1 0.3 2.7 2 1 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 OWF41118.1 - 0.37 11.4 9.7 15 6.3 0.5 3.9 3 1 1 4 4 4 0 SlyX DUF848 PF05852.11 OWF41118.1 - 0.53 10.4 5.8 0.44 10.7 4.1 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DASH_Dam1 PF08653.10 OWF41118.1 - 0.56 10.0 1.7 1.8 8.4 0.3 2.5 2 1 1 3 3 3 0 DASH complex subunit Dam1 ABC_tran_CTD PF16326.5 OWF41118.1 - 1.2 9.4 11.3 4.4 7.6 0.3 3.0 2 1 0 2 2 2 0 ABC transporter C-terminal domain FlxA PF14282.6 OWF41118.1 - 1.7 8.6 16.7 0.93 9.5 9.3 2.3 1 1 1 2 2 2 0 FlxA-like protein YlqD PF11068.8 OWF41118.1 - 2.5 8.5 14.2 1.2 9.5 6.9 2.1 1 1 1 2 2 2 0 YlqD protein GvpK PF05121.12 OWF41118.1 - 2.6 8.1 9.2 1 9.4 1.7 2.9 3 0 0 3 3 3 0 Gas vesicle protein K Fib_alpha PF08702.10 OWF41118.1 - 3.2 7.9 12.8 2.5 8.3 0.6 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4337 PF14235.6 OWF41118.1 - 4.4 7.4 9.9 19 5.3 4.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FapA PF03961.13 OWF41118.1 - 6.3 5.3 13.6 5.5 5.5 8.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 OWF41118.1 - 6.8 7.2 9.9 3.5 8.1 0.2 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 OWF41118.1 - 6.8 6.5 12.8 3.3 7.5 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Acyl-ACP_TE PF01643.17 OWF41119.1 - 4.1e-06 26.3 0.5 7.2e-06 25.5 0.5 1.6 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF41119.1 - 0.00072 20.0 0.3 1.4 9.4 0.2 2.4 2 0 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF41120.1 - 1.5e-08 34.3 0.0 3.4e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF41120.1 - 1.9e-05 25.2 0.5 0.081 13.4 0.3 2.8 2 1 0 2 2 2 2 Thioesterase-like superfamily DB_JBP1 PF18526.1 OWF41120.1 - 0.05 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Thymine dioxygenase JBP1 DNA-binding domain MEIOC PF15189.6 OWF41121.1 - 1.7e-78 261.9 0.8 3.5e-78 261.0 0.8 1.5 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC UPF0139 PF03669.13 OWF41121.1 - 0.0085 15.9 0.0 0.66 9.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0139) CAMSAP_CC1 PF17095.5 OWF41121.1 - 0.072 12.9 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Mito_carr PF00153.27 OWF41122.1 - 4.6e-74 244.4 1.6 9.2e-26 89.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 OWF41122.1 - 1.4e-21 76.7 7.3 9.8e-11 42.0 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF41122.1 - 5.8e-20 69.3 6.4 9.4e-05 21.7 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF41122.1 - 1.5e-18 65.0 9.0 7.2e-05 22.4 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF41122.1 - 2.7e-16 58.2 10.2 1e-05 24.8 0.1 5.1 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF41122.1 - 1.4e-09 37.7 7.9 0.00041 20.2 0.2 4.5 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF41122.1 - 6.5e-08 32.9 1.1 0.0014 18.9 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF41122.1 - 1e-06 28.8 1.7 8.6e-05 22.7 0.2 2.5 1 1 1 2 2 2 1 Dockerin type I domain EF-hand_10 PF14788.6 OWF41122.1 - 0.004 17.0 2.6 0.047 13.6 0.1 3.3 1 1 3 4 4 4 1 EF hand EF-hand_4 PF12763.7 OWF41122.1 - 0.0078 16.2 4.2 0.037 14.0 0.7 2.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF1456 PF07308.13 OWF41122.1 - 0.077 13.3 0.8 1.2 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) Caleosin PF05042.13 OWF41122.1 - 0.11 12.4 0.3 2 8.3 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein Med30 PF11315.8 OWF41122.1 - 0.18 12.0 0.1 0.46 10.7 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 30 Ig_mannosidase PF17753.1 OWF41123.1 - 8.4e-19 67.1 1.4 2.1e-18 65.9 1.4 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 OWF41123.1 - 5e-07 29.8 0.2 1.4e-06 28.4 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 OWF41123.1 - 9.5e-06 24.9 0.1 6.7e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain NOG1_N PF17835.1 OWF41124.1 - 2.7e-56 189.9 2.9 2.7e-56 189.9 2.9 2.8 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOG1 PF06858.14 OWF41124.1 - 7.6e-27 92.9 1.0 1.4e-26 92.0 0.1 1.9 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 OWF41124.1 - 1.3e-23 82.7 2.0 1.3e-23 82.7 2.0 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 OWF41124.1 - 6.1e-20 71.4 0.0 6.7e-19 68.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF41124.1 - 7.6e-13 48.3 0.0 2.3e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF41124.1 - 3.5e-05 23.8 0.0 0.16 11.9 0.0 3.0 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 OWF41124.1 - 0.00011 21.6 0.5 0.00079 18.8 0.1 2.3 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 OWF41124.1 - 0.00051 20.2 0.1 0.012 15.8 0.0 3.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 OWF41124.1 - 0.00058 20.0 6.0 0.11 12.6 0.1 3.1 2 2 1 3 3 3 2 Dynamin family Ras PF00071.22 OWF41124.1 - 0.0021 17.7 0.0 0.0068 16.0 0.0 1.9 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 OWF41124.1 - 0.082 13.3 0.2 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain LCD1 PF09798.9 OWF41124.1 - 1 7.8 7.6 2.1 6.8 7.6 1.4 1 0 0 1 1 1 0 DNA damage checkpoint protein Transformer PF06495.11 OWF41124.1 - 4.6 7.3 15.4 12 5.9 15.4 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein Hormone_3 PF00159.18 OWF41126.1 - 5.8e-12 45.5 2.1 8.8e-12 44.9 2.1 1.3 1 0 0 1 1 1 1 Pancreatic hormone peptide LEAP-2 PF07359.11 OWF41126.1 - 0.012 15.4 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Conotoxin PF02950.17 OWF41126.1 - 0.058 14.4 0.1 0.084 13.9 0.1 1.2 1 0 0 1 1 1 0 Conotoxin Neur_chan_LBD PF02931.23 OWF41127.1 - 2.6e-46 157.8 1.2 3.4e-46 157.4 1.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41127.1 - 1.4e-11 45.0 10.1 1.4e-11 45.0 10.1 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF41128.1 - 1e-35 123.2 1.3 1.2e-35 123.0 1.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41129.1 - 2.6e-11 44.0 11.1 2.6e-11 44.0 11.1 1.8 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_2 PF13903.6 OWF41129.1 - 0.021 14.6 0.1 0.021 14.6 0.1 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Neur_chan_LBD PF02931.23 OWF41129.1 - 0.047 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 OWF41130.1 - 2.6e-43 148.0 1.0 3.5e-43 147.6 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41130.1 - 2.8e-10 40.7 9.6 2.8e-10 40.7 9.6 1.7 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_2 PF13903.6 OWF41130.1 - 0.094 12.5 0.1 0.094 12.5 0.1 2.3 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1700 PF08006.11 OWF41130.1 - 0.7 9.4 0.0 0.7 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) DUF3169 PF11368.8 OWF41130.1 - 6.3 6.2 9.8 0.64 9.5 2.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Neur_chan_LBD PF02931.23 OWF41131.1 - 2.7e-46 157.7 1.2 3.5e-46 157.4 1.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41131.1 - 3.4e-14 53.5 2.0 3.4e-14 53.5 2.0 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF41132.1 - 2.7e-45 154.4 0.5 3.5e-45 154.1 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41132.1 - 4.8e-14 53.0 0.7 8.3e-14 52.2 0.7 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3169 PF11368.8 OWF41132.1 - 8.2 5.9 8.3 3 7.3 3.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Neur_chan_LBD PF02931.23 OWF41133.1 - 2.5e-41 141.5 0.6 3e-41 141.3 0.6 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Amastin PF07344.11 OWF41134.1 - 4.8 7.0 20.0 5.5 6.8 3.7 2.3 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF773 PF05600.12 OWF41135.1 - 6.9e-180 599.1 15.3 7.8e-180 598.9 15.3 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF29 PF01724.16 OWF41135.1 - 0.048 13.9 0.2 0.048 13.9 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF29 NAP PF00956.18 OWF41135.1 - 0.37 9.9 5.8 0.11 11.7 1.7 2.2 1 1 0 2 2 2 0 Nucleosome assembly protein (NAP) BORCS8 PF10167.9 OWF41135.1 - 1.5 8.8 6.9 2.8 7.9 0.1 3.3 4 0 0 4 4 4 0 BLOC-1-related complex sub-unit 8 DUF2203 PF09969.9 OWF41135.1 - 2.1 9.1 8.0 5.1 7.8 0.3 3.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) ALIX_LYPXL_bnd PF13949.6 OWF41135.1 - 6.8 5.9 11.1 0.063 12.6 1.3 2.3 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV zf-B_box PF00643.24 OWF41136.1 - 4.4e-09 36.3 20.5 1e-05 25.6 8.4 4.8 5 1 1 6 6 6 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF41136.1 - 4.2e-07 29.7 11.6 4.2e-07 29.7 11.6 4.1 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF41136.1 - 2.1e-06 27.5 5.8 2.1e-06 27.5 5.8 3.7 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41136.1 - 7e-06 26.0 12.6 7e-06 26.0 12.6 3.9 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF41136.1 - 0.00045 20.3 13.1 0.00045 20.3 13.1 4.1 4 0 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF41136.1 - 0.00056 19.7 8.5 0.00056 19.7 8.5 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 OWF41136.1 - 0.0011 18.6 2.4 0.0011 18.6 2.4 1.4 2 0 0 2 2 2 1 Exonuclease VII, large subunit zf-RING_2 PF13639.6 OWF41136.1 - 0.0027 18.0 11.4 0.0027 18.0 11.4 3.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF41136.1 - 0.0048 16.8 10.5 0.0048 16.8 10.5 4.0 3 0 0 3 3 2 2 zinc-RING finger domain ANAPC4 PF12896.7 OWF41136.1 - 0.0088 15.6 0.8 0.02 14.4 0.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Prok-RING_4 PF14447.6 OWF41136.1 - 0.015 15.1 6.8 0.015 15.1 6.8 4.5 3 2 0 3 3 2 0 Prokaryotic RING finger family 4 SGL PF08450.12 OWF41136.1 - 0.11 12.1 0.0 0.48 10.0 0.0 2.3 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF948 PF06103.11 OWF41136.1 - 0.27 11.5 3.1 0.2 11.9 0.3 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YycI PF09648.10 OWF41136.1 - 0.95 9.0 6.0 1.1 8.8 2.3 2.1 1 1 1 2 2 2 0 YycH protein OmpH PF03938.14 OWF41136.1 - 1.5 9.1 5.2 8.8 6.7 5.2 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF720 PF05302.11 OWF41136.1 - 1.8 8.4 5.9 0.42 10.5 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF720) DUF953 PF06110.11 OWF41141.1 - 3e-40 136.5 0.1 3.4e-40 136.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 OWF41141.1 - 0.03 14.1 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 OWF41141.1 - 0.031 14.5 0.1 0.051 13.8 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like Rhodanese PF00581.20 OWF41142.1 - 1.6e-12 47.9 0.0 2.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain IL17 PF06083.11 OWF41143.1 - 2.6e-06 27.8 0.4 4.7e-06 27.0 0.4 1.5 1 1 0 1 1 1 1 Interleukin-17 Noggin PF05806.12 OWF41143.1 - 3.6e-05 23.8 0.4 4.9e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 Noggin Peptidase_M10 PF00413.24 OWF41144.1 - 4.3e-54 182.6 0.0 6.2e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 OWF41144.1 - 7e-29 99.5 18.3 3.2e-09 36.6 0.6 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 OWF41144.1 - 4e-06 26.9 0.0 9.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 OWF41144.1 - 0.00012 21.8 0.2 0.19 11.4 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 OWF41144.1 - 0.016 15.7 0.1 0.026 15.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 OWF41144.1 - 0.037 13.2 0.3 0.064 12.5 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 OWF41144.1 - 0.053 12.5 0.5 0.083 11.8 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 OWF41144.1 - 0.054 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF41144.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OWF41146.1 - 5.4e-64 214.8 0.2 9.6e-64 214.0 0.2 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 OWF41146.1 - 1.4e-29 101.8 12.5 2.9e-07 30.3 0.1 4.8 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 OWF41146.1 - 1.6e-09 37.8 1.5 2.8e-09 37.0 0.1 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 OWF41146.1 - 0.027 15.0 0.2 0.047 14.2 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF41146.1 - 0.052 13.2 0.1 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 OWF41146.1 - 0.053 13.1 0.7 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 OWF41146.1 - 0.071 12.0 0.7 0.12 11.3 0.7 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 OWF41146.1 - 0.097 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Met-zincin DUF3810 PF12725.7 OWF41146.1 - 0.31 10.4 0.8 4.2 6.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) zf-B_box PF00643.24 OWF41147.1 - 3.8e-07 30.2 2.9 9.8e-07 28.8 2.9 1.8 1 0 0 1 1 1 1 B-box zinc finger Reg_prop PF07494.11 OWF41147.1 - 0.0041 17.2 0.4 13 6.4 0.0 4.1 4 0 0 4 4 4 1 Two component regulator propeller GAT PF03127.14 OWF41147.1 - 0.0081 16.4 0.4 0.0081 16.4 0.4 2.0 2 0 0 2 2 2 1 GAT domain Rsbr_N PF08678.10 OWF41147.1 - 0.026 14.6 0.5 0.051 13.6 0.1 1.7 2 0 0 2 2 2 0 Rsbr N terminal PHF5 PF03660.14 OWF41147.1 - 3.3 7.9 6.7 0.6 10.3 1.3 2.5 3 0 0 3 3 3 0 PHF5-like protein Pkinase PF00069.25 OWF41148.1 - 5.8e-80 268.4 0.0 7.2e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41148.1 - 2.9e-32 112.0 0.0 3.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF41148.1 - 1.8e-08 34.1 0.2 3.6e-07 29.8 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OWF41148.1 - 1.8e-05 23.9 0.8 2.7e-05 23.3 0.8 1.1 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 OWF41148.1 - 0.00092 18.1 1.0 0.0013 17.7 1.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 OWF41148.1 - 0.0012 18.5 0.5 0.6 9.7 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OWF41148.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF41148.1 - 0.0025 17.8 0.0 0.0082 16.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OWF41148.1 - 0.0041 16.7 1.1 0.0066 16.0 1.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 OWF41148.1 - 0.0051 16.4 3.9 0.049 13.2 1.8 2.7 2 1 1 3 3 3 1 RIO1 family Pkinase_fungal PF17667.1 OWF41148.1 - 0.019 13.8 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PACT_coil_coil PF10495.9 OWF41148.1 - 0.034 14.7 0.4 0.081 13.5 0.1 1.8 2 0 0 2 2 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Kelch_3 PF13415.6 OWF41149.1 - 5.7e-43 144.5 6.5 3.2e-09 36.8 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF41149.1 - 7.1e-39 131.6 10.2 3.7e-08 33.3 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 OWF41149.1 - 5.5e-36 121.9 7.4 1.4e-07 31.0 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.6 OWF41149.1 - 1.2e-35 120.9 6.1 3.3e-07 30.1 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF41149.1 - 2.3e-33 113.4 7.4 6.9e-08 32.5 0.0 6.5 5 1 1 6 6 6 6 Kelch motif BTB PF00651.31 OWF41149.1 - 2.2e-32 111.6 0.7 6.5e-17 61.8 0.0 4.1 2 2 2 4 4 4 2 BTB/POZ domain Kelch_2 PF07646.15 OWF41149.1 - 1e-21 76.0 8.1 1.9e-06 27.6 0.2 6.5 6 0 0 6 6 6 3 Kelch motif BACK PF07707.15 OWF41149.1 - 4.3e-06 26.8 2.4 0.002 18.2 0.1 2.6 2 0 0 2 2 2 2 BTB And C-terminal Kelch RAG2 PF03089.14 OWF41149.1 - 0.013 14.5 0.1 0.53 9.2 0.0 3.1 3 1 1 4 4 4 0 Recombination activating protein 2 p450 PF00067.22 OWF41150.1 - 7.4e-114 381.0 0.0 9.4e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Homeodomain PF00046.29 OWF41151.1 - 4.6e-20 71.2 2.1 9.7e-20 70.2 2.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF41151.1 - 1.4e-05 24.9 0.2 4.7e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain LIM PF00412.22 OWF41151.1 - 0.0071 16.6 0.2 0.012 15.8 0.2 1.4 1 0 0 1 1 1 1 LIM domain Acyl-CoA_dh_1 PF00441.24 OWF41152.1 - 2.6e-49 167.3 5.4 4.6e-49 166.5 5.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OWF41152.1 - 1.1e-33 116.2 0.0 4.8e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OWF41152.1 - 1.1e-28 99.2 0.1 2.9e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF41152.1 - 5.5e-23 81.7 2.0 7.7e-23 81.2 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OWF41152.1 - 0.029 14.0 0.0 0.1 12.3 0.0 1.9 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.25 OWF41153.1 - 3e-60 203.8 0.5 9.3e-60 202.2 0.5 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41153.1 - 9.5e-44 149.6 0.1 1.4e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF41153.1 - 1.6e-10 40.8 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF41153.1 - 0.00039 19.5 0.5 0.00068 18.7 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF41153.1 - 0.00048 19.5 0.4 0.00084 18.8 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OWF41153.1 - 0.0096 15.5 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family DUF2977 PF11192.8 OWF41153.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) fn3 PF00041.21 OWF41154.1 - 1.2e-88 291.6 0.3 2e-13 50.5 0.0 9.6 9 0 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF41154.1 - 1.4e-21 76.8 7.2 0.031 14.8 0.1 9.9 8 1 1 9 9 9 7 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF41154.1 - 7.3e-12 45.5 0.0 0.091 13.1 0.0 7.5 8 0 0 8 8 8 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 OWF41154.1 - 1.6e-07 31.6 0.0 23 5.5 0.0 7.6 7 1 1 8 8 8 2 Uncharacterised conserved protein (DUF2369) SusE PF14292.6 OWF41154.1 - 4.3e-06 26.9 3.2 2.5 8.4 0.0 5.1 5 0 0 5 5 5 3 SusE outer membrane protein fn3_2 PF16893.5 OWF41154.1 - 0.0004 20.5 0.0 0.077 13.2 0.0 4.2 5 0 0 5 5 5 1 Fibronectin type III domain EF-hand_1 PF00036.32 OWF41155.1 - 4.4e-10 38.4 1.3 0.001 18.4 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF41155.1 - 3e-09 37.2 0.1 1.3e-08 35.1 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF41155.1 - 3.3e-08 32.8 0.2 0.00012 21.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OWF41155.1 - 0.0023 17.7 0.1 0.0073 16.1 0.1 2.0 1 1 0 1 1 1 1 EF-hand domain pair V_ATPase_I PF01496.19 OWF41155.1 - 0.0061 14.5 4.5 0.0085 14.1 4.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Lip_prot_lig_C PF10437.9 OWF41155.1 - 0.0067 16.4 0.6 1.1 9.2 0.2 3.3 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus EF-hand_5 PF13202.6 OWF41155.1 - 0.046 13.2 0.3 2.9 7.6 0.1 2.7 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 OWF41155.1 - 0.056 13.8 1.8 0.08 13.3 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FAM150 PF15129.6 OWF41155.1 - 0.1 12.8 2.2 0.15 12.2 0.8 2.0 1 1 1 2 2 2 0 FAM150 family DUF745 PF05335.13 OWF41155.1 - 0.19 11.5 7.1 0.31 10.8 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 OWF41155.1 - 0.23 11.0 4.6 0.38 10.3 4.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit RTX PF02382.15 OWF41155.1 - 0.25 11.0 2.0 0.45 10.2 2.0 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein Fib_alpha PF08702.10 OWF41155.1 - 0.41 10.8 11.0 1.8 8.7 2.1 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GAS PF13851.6 OWF41155.1 - 0.64 9.3 17.3 0.68 9.2 15.6 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CorA PF01544.18 OWF41155.1 - 0.7 9.2 10.0 1.1 8.5 5.6 2.9 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Nsp1_C PF05064.13 OWF41155.1 - 1.1 9.0 10.0 2.3 8.0 4.6 3.5 2 2 2 4 4 4 0 Nsp1-like C-terminal region NPV_P10 PF05531.12 OWF41155.1 - 1.7 9.2 6.8 24 5.5 0.1 4.2 5 0 0 5 5 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 OWF41155.1 - 2.4 8.6 5.0 6.1 7.3 0.5 3.4 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.6 OWF41155.1 - 4.9 7.6 7.1 12 6.4 4.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TMPIT PF07851.13 OWF41155.1 - 7.1 5.8 10.4 0.31 10.3 1.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein SSF PF00474.17 OWF41156.1 - 6.1e-40 137.3 29.6 6.1e-40 137.3 29.6 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family NHL PF01436.21 OWF41157.1 - 1.1e-09 37.9 1.3 4.5e-06 26.4 0.0 4.1 4 0 0 4 4 4 2 NHL repeat SGL PF08450.12 OWF41157.1 - 0.00025 20.7 0.0 0.85 9.2 0.0 2.8 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region TPR_1 PF00515.28 OWF41158.1 - 7.1e-34 114.3 24.9 4e-08 32.8 0.2 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat DUF1736 PF08409.11 OWF41158.1 - 1.1e-29 102.3 1.6 1.1e-29 102.3 1.6 1.9 2 0 0 2 2 1 1 Domain of unknown function (DUF1736) TPR_8 PF13181.6 OWF41158.1 - 2.8e-27 92.6 18.0 7.6e-05 22.6 0.1 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 OWF41158.1 - 2.3e-23 80.4 21.5 0.00045 20.1 0.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 OWF41158.1 - 8.6e-23 79.8 21.6 9.3e-05 22.0 0.3 8.7 5 2 4 9 9 9 6 TPR repeat TPR_17 PF13431.6 OWF41158.1 - 1.1e-22 78.7 25.2 8e-05 22.7 0.5 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 OWF41158.1 - 1.4e-18 66.9 15.6 1.7e-08 34.6 1.5 4.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 OWF41158.1 - 1.1e-15 57.9 4.8 6.6e-05 23.5 0.1 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OWF41158.1 - 6.1e-11 41.8 25.9 1.4e-06 27.9 0.3 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF41158.1 - 4e-10 39.6 6.5 0.56 11.2 0.2 6.5 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OWF41158.1 - 5.5e-09 35.4 11.5 0.42 10.8 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF41158.1 - 1.9e-07 31.5 16.3 0.0017 18.8 1.3 5.1 1 1 4 6 6 6 4 Tetratricopeptide repeat FAT PF02259.23 OWF41158.1 - 0.00027 20.3 5.1 0.098 11.9 0.1 2.6 1 1 0 2 2 2 2 FAT domain TPR_6 PF13174.6 OWF41158.1 - 0.00068 20.1 6.9 1.2 9.9 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OWF41158.1 - 0.012 14.8 8.5 0.41 9.8 0.1 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OWF41158.1 - 0.04 14.5 0.2 1.7 9.5 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2301 PF10063.9 OWF41158.1 - 0.072 13.5 1.1 0.24 11.8 1.1 1.9 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) ANAPC5 PF12862.7 OWF41158.1 - 0.073 13.2 0.2 1.1 9.4 0.2 2.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 SNAP PF14938.6 OWF41158.1 - 0.11 11.8 5.1 0.047 13.1 0.4 2.2 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_20 PF14561.6 OWF41158.1 - 0.86 10.0 4.3 15 6.0 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat ShK PF01549.24 OWF41160.1 - 0.0024 18.4 23.3 0.011 16.2 9.2 3.7 4 1 0 4 4 4 2 ShK domain-like MFS_1 PF07690.16 OWF41161.1 - 2.9e-41 141.6 42.5 8.4e-31 107.2 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OWF41161.1 - 2.8e-05 22.8 25.6 0.00013 20.7 8.0 3.5 2 1 1 3 3 3 3 MFS/sugar transport protein WD40 PF00400.32 OWF41163.1 - 4e-14 52.8 8.1 0.091 13.7 0.1 8.0 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF41163.1 - 6.9e-13 48.7 1.4 0.028 14.7 0.0 6.9 5 1 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OWF41163.1 - 0.024 14.2 0.7 1.8 8.1 0.0 3.2 2 1 1 3 3 3 0 PQQ-like domain BBS2_N PF14781.6 OWF41163.1 - 0.086 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal 7tm_1 PF00001.21 OWF41164.1 - 4.1e-42 144.3 17.3 5.9e-42 143.8 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF41164.1 - 6.2e-14 52.0 20.4 8.6e-14 51.5 20.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF41164.1 - 0.00016 21.4 22.8 0.00034 20.3 22.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF41164.1 - 0.00072 19.4 13.7 0.00072 19.4 13.7 2.1 1 1 0 2 2 2 1 Olfactory receptor FAM72 PF14976.6 OWF41166.1 - 0.0026 17.9 2.2 0.0026 17.9 2.2 1.8 1 1 1 2 2 2 1 FAM72 protein DUF2509 PF10713.9 OWF41167.1 - 0.021 15.0 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) SPATIAL PF15256.6 OWF41169.1 - 4.1e-60 203.5 0.0 6.7e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 SPATIAL DUF3211 PF11485.8 OWF41170.1 - 0.0026 18.0 6.1 1.5 9.0 1.3 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3211) GP120 PF00516.18 OWF41170.1 - 0.014 14.1 0.1 14 4.1 0.0 3.4 1 1 1 3 3 3 0 Envelope glycoprotein GP120 Herpes_UL16 PF03044.14 OWF41170.1 - 0.094 12.0 0.3 8.7 5.5 0.0 3.2 1 1 2 4 4 4 0 Herpesvirus UL16/UL94 family Galactosyl_T PF01762.21 OWF41171.1 - 4.7e-45 153.8 0.0 6.6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Rimk_N PF18030.1 OWF41172.1 - 1.3e-06 28.6 9.7 20 5.7 0.0 8.1 1 1 7 9 9 9 2 RimK PreATP-grasp domain CopK PF11525.8 OWF41172.1 - 0.00012 21.6 1.3 0.62 9.7 0.0 4.7 4 1 1 5 5 5 2 Copper resistance protein K Polysacc_synt_2 PF02719.15 OWF41172.1 - 0.0079 15.4 9.6 0.45 9.6 0.3 3.8 2 2 3 5 5 5 2 Polysaccharide biosynthesis protein DUF3225 PF11533.8 OWF41172.1 - 0.017 14.8 24.3 0.39 10.4 0.5 5.7 1 1 5 6 6 6 0 Protein of unknown function (DUF3225) Vault_2 PF17794.1 OWF41172.1 - 0.43 11.0 7.3 30 5.1 0.2 5.3 2 2 2 5 5 5 0 Major Vault Protein repeat domain TNT PF14021.6 OWF41173.1 - 0.089 13.4 5.6 2.8 8.6 0.4 4.0 1 1 2 3 3 3 0 Tuberculosis necrotizing toxin Rimk_N PF18030.1 OWF41173.1 - 0.53 10.7 3.9 86 3.6 0.0 4.4 4 2 1 5 5 5 0 RimK PreATP-grasp domain DUF3225 PF11533.8 OWF41174.1 - 0.042 13.6 8.3 4.3 7.1 0.5 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF3225) Rimk_N PF18030.1 OWF41175.1 - 0.17 12.3 0.1 13 6.3 0.0 2.9 1 1 1 2 2 2 0 RimK PreATP-grasp domain TNT PF14021.6 OWF41175.1 - 0.18 12.4 1.0 12 6.5 0.3 2.8 1 1 1 2 2 2 0 Tuberculosis necrotizing toxin DUF3432 PF11914.8 OWF41176.1 - 0.032 14.5 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Rimk_N PF18030.1 OWF41176.1 - 0.13 12.7 0.1 0.52 10.7 0.0 2.0 1 1 1 2 2 2 0 RimK PreATP-grasp domain LMWSLP_N PF12211.8 OWF41176.1 - 0.18 11.4 1.2 0.23 11.1 0.8 1.4 1 1 0 1 1 1 0 Low molecular weight S layer protein N terminal Polysacc_synt_2 PF02719.15 OWF41176.1 - 0.31 10.1 1.4 0.45 9.6 0.4 1.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein PqqA PF08042.11 OWF41176.1 - 2 8.6 10.4 25 5.1 0.7 4.1 4 0 0 4 4 4 0 PqqA family EF-hand_5 PF13202.6 OWF41177.1 - 1.2e-05 24.5 0.1 2.8e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OWF41177.1 - 0.00025 20.4 0.1 0.0005 19.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OWF41177.1 - 0.001 19.4 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF41177.1 - 0.0011 18.7 0.1 0.0033 17.2 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 OWF41177.1 - 0.0066 16.3 0.1 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair ZFYVE21_C PF16696.5 OWF41179.1 - 4.6e-28 97.6 0.2 6.2e-28 97.1 0.2 1.2 1 0 0 1 1 1 1 Zinc finger FYVE domain-containing protein 21 C-terminus FYVE PF01363.21 OWF41179.1 - 8.8e-13 48.2 22.3 8.8e-13 48.2 22.3 1.7 2 0 0 2 2 2 1 FYVE zinc finger Bys1 PF04681.12 OWF41179.1 - 0.047 13.6 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein DUF2251 PF10008.9 OWF41179.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) GDA1_CD39 PF01150.17 OWF41180.1 - 1.3e-74 251.4 0.0 1.7e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OWF41180.1 - 0.049 13.1 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Ank_2 PF12796.7 OWF41182.1 - 1.8e-52 175.8 9.2 2.7e-14 53.5 0.1 5.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF41182.1 - 1.5e-50 168.9 3.4 1.1e-09 38.7 0.0 6.7 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41182.1 - 6.6e-43 139.8 5.3 0.00029 21.0 0.0 10.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 OWF41182.1 - 3.2e-37 126.1 11.7 6.5e-08 32.7 0.2 8.3 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 OWF41182.1 - 9.7e-35 117.5 18.7 0.00045 20.5 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat p450 PF00067.22 OWF41183.1 - 1.7e-91 307.3 0.9 2e-91 307.1 0.9 1.0 1 0 0 1 1 1 1 Cytochrome P450 TAF PF02969.17 OWF41183.1 - 0.011 15.8 0.1 0.035 14.3 0.1 1.8 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF1146 PF06612.11 OWF41183.1 - 0.087 12.9 1.3 0.28 11.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) Carn_acyltransf PF00755.20 OWF41184.1 - 3.1e-175 584.2 0.5 3.6e-175 584.0 0.5 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPBP PF02517.16 OWF41185.1 - 1.1e-17 64.2 2.4 1.1e-17 64.2 2.4 3.0 4 0 0 4 4 4 1 CPBP intramembrane metalloprotease GH43_C PF16369.5 OWF41187.1 - 0.014 16.0 0.4 0.033 14.8 0.4 1.6 1 0 0 1 1 1 0 C-terminal lipocalin-like domain DUF485 PF04341.12 OWF41187.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 TMPIT PF07851.13 OWF41187.1 - 0.69 9.1 3.5 0.18 11.0 0.6 1.4 2 0 0 2 2 2 0 TMPIT-like protein L6_membrane PF05805.12 OWF41189.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 L6 membrane protein LPMO_10 PF03067.15 OWF41190.1 - 8.2e-31 108.2 1.3 1.3e-30 107.5 1.3 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Tam41_Mmp37 PF09139.11 OWF41191.1 - 4.8e-101 338.4 0.0 5.4e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Complex1_LYR PF05347.15 OWF41192.1 - 7.1e-11 42.0 2.8 1.5e-10 41.0 2.8 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OWF41192.1 - 0.00068 20.3 1.2 0.0011 19.7 1.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like DUF438 PF04282.13 OWF41192.1 - 0.067 13.2 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF438) Complex1_LYR_1 PF13232.6 OWF41192.1 - 0.11 13.1 1.4 0.96 10.1 0.1 2.0 1 1 1 2 2 2 0 Complex1_LYR-like JAMP PF05571.12 OWF41193.1 - 6.6e-119 396.9 16.4 7.4e-119 396.7 16.4 1.0 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein EI24 PF07264.11 OWF41193.1 - 0.46 10.7 15.5 1.3 9.2 15.3 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Metallophos PF00149.28 OWF41194.1 - 3.3e-09 37.5 0.4 6.2e-09 36.6 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF41194.1 - 0.00045 20.4 0.0 0.0018 18.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThiF PF00899.21 OWF41195.1 - 3.1e-63 213.4 0.0 5e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OWF41195.1 - 1.4e-05 25.6 0.0 4.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 OWF41195.1 - 0.067 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OWF41195.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OWF41195.1 - 0.47 10.7 2.6 1.7 9.0 1.2 2.5 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Acylphosphatase PF00708.18 OWF41196.1 - 5.7e-25 87.5 0.6 6.3e-25 87.4 0.6 1.0 1 0 0 1 1 1 1 Acylphosphatase AAA_33 PF13671.6 OWF41197.1 - 6e-28 97.8 0.0 1.2e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain SAP PF02037.27 OWF41197.1 - 3e-13 49.2 5.0 3.2e-13 49.1 3.4 2.0 2 0 0 2 2 2 1 SAP domain SPRY PF00622.28 OWF41197.1 - 1.8e-12 47.4 0.1 1.8e-12 47.4 0.1 2.7 2 1 0 2 2 2 1 SPRY domain AAA_18 PF13238.6 OWF41197.1 - 3.9e-05 24.2 0.1 0.00013 22.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OWF41197.1 - 0.004 17.6 0.5 0.032 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OWF41197.1 - 0.0076 15.5 0.3 0.43 9.8 0.3 2.9 1 1 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 OWF41197.1 - 0.021 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 OWF41197.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.23 OWF41198.1 - 1.6e-75 254.0 3.2 3.8e-75 252.7 3.2 1.7 1 0 0 1 1 1 1 Papain family cysteine protease Cystatin PF00031.21 OWF41198.1 - 2.5e-24 85.3 3.8 2e-07 31.2 0.0 3.5 3 0 0 3 3 3 3 Cystatin domain SQAPI PF16845.5 OWF41198.1 - 9.6e-22 77.1 4.2 2.3e-08 34.3 0.1 3.6 3 0 0 3 3 3 3 Aspartic acid proteinase inhibitor Inhibitor_I29 PF08246.12 OWF41198.1 - 5.5e-10 39.5 0.4 1.7e-09 38.0 0.4 1.9 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF41198.1 - 1.8e-06 27.0 0.3 0.00082 18.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase C1-like family BTB PF00651.31 OWF41199.1 - 1.2e-22 80.2 0.1 4.3e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF41199.1 - 1.3e-11 44.5 0.1 5.1e-11 42.6 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch zf-H2C2_2 PF13465.6 OWF41199.1 - 2.5e-09 37.1 74.8 0.00088 19.6 4.3 10.0 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2 PF00096.26 OWF41199.1 - 1.1e-07 31.8 91.1 0.0016 18.8 2.0 9.7 9 0 0 9 9 9 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF41199.1 - 2.1e-05 25.0 82.2 0.0074 17.0 1.5 9.7 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF41199.1 - 0.00089 19.5 42.3 0.0021 18.3 4.1 6.1 3 2 3 6 6 6 3 C2H2-type zinc ribbon zf-met PF12874.7 OWF41199.1 - 0.0071 16.7 2.9 0.0071 16.7 2.9 7.2 8 0 0 8 8 8 4 Zinc-finger of C2H2 type MCM_OB PF17207.3 OWF41199.1 - 0.01 15.7 0.6 0.01 15.7 0.6 3.8 4 1 1 5 5 5 0 MCM OB domain TMEM223 PF14640.6 OWF41200.1 - 4.4e-30 105.0 0.0 6.3e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 RSN1_7TM PF02714.15 OWF41201.1 - 5.9e-49 166.8 25.3 5.9e-49 166.8 25.3 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OWF41201.1 - 1.6e-36 126.2 0.1 2.1e-36 125.8 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OWF41201.1 - 7e-23 81.1 3.2 7e-23 81.1 3.2 3.9 2 2 1 3 3 3 1 Late exocytosis, associated with Golgi transport Meiotic_rec114 PF03525.14 OWF41201.1 - 0.049 12.6 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Meiotic recombination protein rec114 DUF962 PF06127.11 OWF41201.1 - 0.3 11.2 9.6 72 3.6 1.2 5.0 3 1 1 4 4 4 0 Protein of unknown function (DUF962) Y_phosphatase PF00102.27 OWF41202.1 - 1.8e-68 230.6 0.3 1.8e-68 230.6 0.3 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase FERM_N PF09379.10 OWF41202.1 - 5.8e-19 67.8 1.2 1.3e-18 66.7 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 OWF41202.1 - 8.5e-16 58.4 0.1 8.5e-16 58.4 0.1 2.6 3 0 0 3 3 3 1 FERM central domain FERM_C PF09380.10 OWF41202.1 - 1.3e-07 31.9 0.0 3.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.20 OWF41202.1 - 4.4e-05 23.3 0.0 0.00014 21.6 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF41202.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OWF41202.1 - 0.034 13.7 0.2 0.09 12.4 0.2 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family CENP-F_N PF10481.9 OWF41203.1 - 1.2e-66 225.5 102.2 1.4e-35 123.4 40.4 23.1 4 3 18 23 23 23 2 Cenp-F N-terminal domain ATG16 PF08614.11 OWF41203.1 - 3.9e-06 27.2 40.3 0.00013 22.3 19.1 36.8 3 2 29 34 34 34 17 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OWF41203.1 - 1.3e-05 25.2 50.1 0.00015 21.8 22.7 38.6 4 4 34 39 39 39 16 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 OWF41203.1 - 0.0018 17.7 10.3 0.0018 17.7 10.3 42.7 3 2 35 44 44 44 13 Protein of unknown function (DUF3450) DUF4201 PF13870.6 OWF41203.1 - 0.0028 17.4 12.3 0.0028 17.4 12.3 37.0 7 5 25 36 36 36 10 Domain of unknown function (DUF4201) Nucleoporin_FG PF13634.6 OWF41203.1 - 2.2 9.2 24.2 12 6.8 24.2 2.3 1 1 0 1 1 1 0 Nucleoporin FG repeat region Cpn60_TCP1 PF00118.24 OWF41204.1 - 1.9e-159 531.4 12.5 2.2e-159 531.2 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcfK PF14058.6 OWF41204.1 - 0.0077 16.5 1.1 0.009 16.3 0.0 1.6 2 0 0 2 2 2 1 PcfK-like protein DUF3055 PF11256.8 OWF41205.1 - 0.016 15.4 33.7 6.7 7.1 1.1 7.9 1 1 8 9 9 9 0 Protein of unknown function (DUF3055) Pentapeptide_4 PF13599.6 OWF41205.1 - 0.28 11.4 11.8 9.9 6.4 0.8 3.3 1 1 0 2 2 2 0 Pentapeptide repeats (9 copies) CAP_GLY PF01302.25 OWF41205.1 - 0.44 10.6 4.0 2 8.5 0.1 4.0 1 1 4 5 5 5 0 CAP-Gly domain DUF3055 PF11256.8 OWF41206.1 - 0.024 14.9 29.4 2.8 8.2 0.9 8.0 3 3 7 10 10 10 0 Protein of unknown function (DUF3055) CAP_GLY PF01302.25 OWF41207.1 - 0.074 13.1 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 CAP-Gly domain Hexapep_loop PF18776.1 OWF41208.1 - 0.022 14.4 1.1 1.1e+02 2.5 0.0 5.8 7 1 0 7 7 7 0 Hexapeptide repeat including loop Gp58 PF07902.11 OWF41209.1 - 0.00071 18.0 5.1 0.0034 15.7 5.1 2.3 1 1 0 1 1 1 1 gp58-like protein IFT57 PF10498.9 OWF41209.1 - 0.0049 15.9 3.1 0.14 11.1 0.2 2.6 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 APG17 PF04108.12 OWF41209.1 - 0.11 11.6 6.9 0.073 12.2 1.8 2.4 1 1 2 3 3 3 0 Autophagy protein Apg17 Herpes_BLLF1 PF05109.13 OWF41209.1 - 0.27 9.2 26.3 0.38 8.7 26.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Fib_alpha PF08702.10 OWF41209.1 - 2.5 8.3 6.0 40 4.4 0.4 2.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DASH_Dad4 PF08650.10 OWF41209.1 - 4.9 7.2 11.4 50 4.0 0.1 4.6 2 2 2 4 4 4 0 DASH complex subunit Dad4 EGF PF00008.27 OWF41210.1 - 8.9e-47 157.0 164.7 2.9e-09 37.1 12.2 12.1 11 1 0 11 11 10 8 EGF-like domain hEGF PF12661.7 OWF41210.1 - 5.7e-34 115.6 130.7 2.7e-07 31.0 6.0 11.9 12 0 0 12 12 12 8 Human growth factor-like EGF DSL PF01414.19 OWF41210.1 - 3.3e-24 84.9 8.9 3.3e-24 84.9 8.9 7.7 4 2 3 7 7 6 1 Delta serrate ligand MNNL PF07657.13 OWF41210.1 - 1.7e-22 79.2 2.3 1.7e-22 79.2 2.3 4.0 3 1 1 4 4 1 1 N terminus of Notch ligand EGF_2 PF07974.13 OWF41210.1 - 4.1e-10 39.9 189.9 0.0062 16.9 8.4 12.3 12 0 0 12 12 12 7 EGF-like domain EGF_CA PF07645.15 OWF41210.1 - 0.00023 21.3 162.6 0.0019 18.4 10.0 11.8 6 3 5 11 11 8 7 Calcium-binding EGF domain Orf78 PF06024.12 OWF41210.1 - 0.037 14.3 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) CD34_antigen PF06365.12 OWF41210.1 - 0.04 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SKG6 PF08693.10 OWF41210.1 - 0.052 13.0 3.6 0.089 12.2 3.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.12 OWF41210.1 - 0.089 12.6 1.1 0.19 11.6 1.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Cadherin_C_2 PF16492.5 OWF41210.1 - 0.36 11.6 1.4 1.1 10.0 0.0 2.6 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Adipogenin PF15202.6 OWF41210.1 - 4 7.5 7.3 0.15 12.1 0.4 2.2 3 0 0 3 3 2 0 Adipogenin NIF PF03031.18 OWF41211.1 - 2.2e-36 125.0 0.0 3.5e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3350 PF11830.8 OWF41213.1 - 0.12 12.7 0.8 0.5 10.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3350) DUF3253 PF11625.8 OWF41213.1 - 0.14 12.5 0.4 1.5 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3253) TauD PF02668.16 OWF41215.1 - 8e-28 98.0 0.0 1.3e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OWF41215.1 - 2.3e-15 57.0 1.7 5.6e-15 55.7 0.2 2.5 2 1 0 3 3 3 1 Protein of unknown function (DUF971) 7tm_1 PF00001.21 OWF41216.1 - 7.2e-12 45.2 22.1 9e-12 44.9 21.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GMP_PDE_delta PF05351.11 OWF41217.1 - 5.2e-44 150.1 0.0 6.7e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit CdiI_3 PF18616.1 OWF41217.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 CDI immunity proteins TPR_1 PF00515.28 OWF41218.1 - 2.2e-22 77.9 5.9 5.4e-06 26.0 0.0 5.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 OWF41218.1 - 2e-18 65.8 2.0 3.3e-06 26.7 0.0 5.6 2 2 4 6 6 6 3 TPR repeat TPR_2 PF07719.17 OWF41218.1 - 2.8e-18 64.5 9.3 0.00084 19.3 0.4 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF41218.1 - 1.2e-15 56.9 4.2 0.003 18.2 0.0 7.1 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF41218.1 - 1.2e-14 53.3 0.7 0.023 14.9 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF41218.1 - 4.9e-13 49.5 4.8 0.0002 21.9 0.3 4.4 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 OWF41218.1 - 1.2e-12 48.2 5.2 0.00026 21.4 0.0 4.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF41218.1 - 8.2e-12 45.2 5.5 1.8e-06 28.2 1.2 3.9 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OWF41218.1 - 1.8e-10 40.4 5.2 0.0079 16.5 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF41218.1 - 5.4e-08 32.3 0.1 0.54 10.4 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF41218.1 - 3.3e-07 30.3 0.9 0.049 13.8 0.0 3.5 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF41218.1 - 1.6e-06 27.8 4.2 0.029 14.2 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF41218.1 - 2.1e-05 24.8 0.6 4.1 8.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 OWF41218.1 - 0.0005 20.3 1.0 4.6 7.7 0.0 3.9 1 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF41218.1 - 0.00084 19.5 3.5 0.22 11.8 0.1 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OWF41218.1 - 0.0042 16.3 0.2 1.5 8.0 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF41218.1 - 0.019 15.0 0.1 17 5.6 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MAS20 PF02064.15 OWF41218.1 - 0.038 14.1 1.7 12 6.0 0.0 3.5 3 1 0 4 4 4 0 MAS20 protein import receptor TPR_3 PF07720.12 OWF41218.1 - 0.04 13.9 0.0 9.6 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat LpqV PF17301.2 OWF41218.1 - 0.087 13.1 0.0 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Putative lipoprotein LpqV MeaB PF03308.16 OWF41218.1 - 0.24 10.3 0.2 0.41 9.6 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AGTRAP PF06396.11 OWF41219.1 - 4.2e-35 120.7 0.0 5.3e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF1713 PF08213.11 OWF41220.1 - 0.0021 18.0 16.2 0.0021 18.0 16.2 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) ABC_trans_N PF14510.6 OWF41220.1 - 0.27 11.9 1.0 1.4 9.5 1.0 2.1 1 1 0 1 1 1 0 ABC-transporter N-terminal Rap_GAP PF02145.15 OWF41221.1 - 1.1e-64 217.4 0.0 2.1e-64 216.5 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP LIM PF00412.22 OWF41221.1 - 1.6e-07 31.4 2.9 1.6e-07 31.4 2.9 2.0 2 0 0 2 2 2 1 LIM domain GoLoco PF02188.17 OWF41221.1 - 3.8e-06 26.3 2.1 8.3e-06 25.2 2.1 1.6 1 0 0 1 1 1 1 GoLoco motif CENP-F_leu_zip PF10473.9 OWF41221.1 - 0.06 13.4 1.6 0.17 11.9 1.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 OWF41221.1 - 0.28 11.3 2.2 0.62 10.2 2.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor Chordopox_RPO7 PF05864.12 OWF41221.1 - 0.95 9.8 4.1 3.6 7.9 1.1 2.6 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF1681 PF07933.14 OWF41222.1 - 8.3e-59 197.5 0.0 1.1e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Peptidase_C14 PF00656.22 OWF41223.1 - 3.9e-22 79.4 0.1 6.5e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 OWF41223.1 - 1.9e-10 40.6 0.0 1.5e-09 37.8 0.0 2.5 2 1 1 3 3 3 1 Caspase recruitment domain CARD_2 PF16739.5 OWF41223.1 - 3.1e-06 27.1 0.0 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain DUF3385 PF11865.8 OWF41223.1 - 0.077 12.9 0.1 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Mog1 PF04603.12 OWF41224.1 - 2.2e-38 131.7 0.2 3e-38 131.3 0.2 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Peptidase_C14 PF00656.22 OWF41225.1 - 1.1e-09 38.6 0.3 2.2e-09 37.7 0.3 1.5 1 1 0 1 1 1 1 Caspase domain PB1 PF00564.24 OWF41225.1 - 2.6e-09 36.9 0.3 6.5e-09 35.6 0.3 1.7 1 0 0 1 1 1 1 PB1 domain FabA PF07977.13 OWF41225.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 FabA-like domain 7tm_1 PF00001.21 OWF41226.1 - 3.1e-22 79.2 9.2 4.3e-22 78.7 9.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CCDC74_C PF14917.6 OWF41226.1 - 0.035 14.6 0.1 0.072 13.6 0.1 1.5 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal DUF1103 PF06513.11 OWF41226.1 - 1.6 8.3 4.6 0.31 10.6 0.1 1.9 2 1 1 3 3 3 0 Repeat of unknown function (DUF1103) DUF2569 PF10754.9 OWF41226.1 - 7.5 7.0 12.8 0.2 12.1 1.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) Fuseless PF15993.5 OWF41227.1 - 3.8e-73 246.3 21.7 4.5e-73 246.1 21.7 1.0 1 0 0 1 1 1 1 Fuseless HLH PF00010.26 OWF41228.1 - 1.2e-13 50.7 1.5 2.8e-13 49.6 1.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF41228.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 Hairy Orange SGIII PF15467.6 OWF41228.1 - 0.00093 18.6 0.4 0.0014 18.0 0.4 1.2 1 0 0 1 1 1 1 Secretogranin-3 DUF769 PF05590.11 OWF41228.1 - 0.15 11.5 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) Ig_3 PF13927.6 OWF41229.1 - 7.5e-206 667.3 24.2 4.4e-15 56.0 0.0 16.7 16 0 0 16 16 16 16 Immunoglobulin domain I-set PF07679.16 OWF41229.1 - 4.2e-197 638.9 0.0 9.2e-15 54.5 0.0 16.6 16 0 0 16 16 16 16 Immunoglobulin I-set domain Ldl_recept_a PF00057.18 OWF41229.1 - 6.5e-174 563.8 423.3 2.3e-11 43.7 13.2 23.1 23 0 0 23 23 20 20 Low-density lipoprotein receptor domain class A ig PF00047.25 OWF41229.1 - 2.8e-127 415.2 5.6 1.5e-08 34.7 0.1 16.6 16 0 0 16 16 16 16 Immunoglobulin domain Ig_2 PF13895.6 OWF41229.1 - 1.2e-126 413.2 11.6 2.4e-08 34.2 0.0 17.1 15 1 1 16 16 16 16 Immunoglobulin domain Laminin_B PF00052.18 OWF41229.1 - 3.5e-97 321.6 0.0 2.8e-35 121.2 0.0 3.9 4 0 0 4 4 4 3 Laminin B (Domain IV) Laminin_G_1 PF00054.23 OWF41229.1 - 4.3e-67 224.3 0.9 1.1e-22 80.6 0.0 3.6 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 OWF41229.1 - 1.2e-61 206.9 1.0 2e-19 70.4 0.0 3.8 3 1 0 3 3 3 3 Laminin G domain V-set PF07686.17 OWF41229.1 - 2.4e-60 201.5 31.2 0.0015 18.6 0.1 26.5 16 13 10 26 26 26 14 Immunoglobulin V-set domain Laminin_EGF PF00053.24 OWF41229.1 - 2e-29 101.5 155.0 5e-10 39.4 18.0 24.3 21 4 4 25 25 14 11 Laminin EGF domain Ig_6 PF18452.1 OWF41229.1 - 6e-28 96.2 0.0 0.058 13.0 0.0 14.7 15 0 0 15 15 15 6 Immunoglobulin domain Izumo-Ig PF16706.5 OWF41229.1 - 3.5e-20 71.9 0.6 0.3 11.2 0.0 14.2 16 0 0 16 16 15 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 OWF41229.1 - 5.9e-18 64.7 28.1 0.025 14.7 0.0 13.9 15 0 0 15 15 15 4 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 OWF41229.1 - 5.3e-08 32.8 0.0 84 3.3 0.0 10.5 12 0 0 12 12 12 0 C17orf99 Ig domain SEA PF01390.20 OWF41229.1 - 7.4e-07 29.2 0.5 1.6e-06 28.2 0.5 1.6 1 0 0 1 1 1 1 SEA domain EGF PF00008.27 OWF41229.1 - 7.3e-06 26.2 36.7 0.00019 21.6 6.9 25.6 27 3 1 28 28 14 4 EGF-like domain Laminin_G_3 PF13385.6 OWF41229.1 - 5.1e-05 23.5 2.8 0.072 13.2 0.1 3.7 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Adeno_E3_CR1 PF02440.15 OWF41229.1 - 0.00014 21.5 6.4 9.7 6.0 0.0 8.7 9 0 0 9 9 9 0 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 OWF41229.1 - 0.00038 20.6 0.0 27 5.0 0.0 5.8 7 0 0 7 7 4 0 Natural killer cell receptor 2B4 hEGF PF12661.7 OWF41229.1 - 0.0052 17.4 5.3 0.0052 17.4 5.3 24.4 26 1 0 26 26 16 2 Human growth factor-like EGF CarboxypepD_reg PF13620.6 OWF41229.1 - 2 8.7 8.5 0.77 10.1 1.4 4.0 4 0 0 4 4 3 0 Carboxypeptidase regulatory-like domain Pyocin_S PF06958.12 OWF41229.1 - 6.1 7.4 9.6 29 5.2 0.0 5.5 6 1 0 7 7 5 0 S-type Pyocin PH PF00169.29 OWF41230.1 - 4.3e-15 56.1 0.0 3.8e-09 37.0 0.0 3.1 3 0 0 3 3 3 2 PH domain RUN PF02759.19 OWF41230.1 - 3.3e-13 49.8 0.4 1e-12 48.2 0.4 1.9 1 1 0 1 1 1 1 RUN domain Stap_Strp_tox_C PF02876.17 OWF41230.1 - 0.18 12.1 6.4 1 9.7 2.2 3.6 4 0 0 4 4 4 0 Staphylococcal/Streptococcal toxin, beta-grasp domain His_Phos_1 PF00300.22 OWF41231.1 - 5.8e-28 97.9 0.4 9.3e-25 87.4 0.3 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF3919 PF13057.6 OWF41231.1 - 0.037 13.6 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) MRP-L47 PF06984.13 OWF41233.1 - 1.9e-34 117.6 2.4 4e-34 116.6 2.4 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Band_7 PF01145.25 OWF41234.1 - 4.4e-23 82.2 1.6 6.7e-23 81.6 1.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 OWF41234.1 - 0.00022 21.3 2.1 0.00041 20.4 2.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 dNK PF01712.19 OWF41235.1 - 2.7e-57 193.9 0.1 3.1e-57 193.7 0.1 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 OWF41235.1 - 1.8e-06 28.6 0.1 3.8e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF41235.1 - 2.7e-06 27.6 0.0 3e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OWF41235.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain NFRKB_winged PF14465.6 OWF41235.1 - 0.0021 18.2 0.4 0.34 11.1 0.4 2.4 1 1 0 1 1 1 1 NFRKB Winged Helix-like Thymidylate_kin PF02223.17 OWF41235.1 - 0.0079 15.9 0.1 0.077 12.7 0.1 2.2 1 1 0 1 1 1 1 Thymidylate kinase G-alpha PF00503.20 OWF41235.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit KAP_NTPase PF07693.14 OWF41235.1 - 0.014 14.7 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 OWF41235.1 - 0.034 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF577 PF04510.12 OWF41235.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF577) AAA_29 PF13555.6 OWF41235.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 OWF41235.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase NACHT PF05729.12 OWF41235.1 - 0.16 11.8 0.1 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain HTH_45 PF14947.6 OWF41236.1 - 0.016 15.2 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix zf-B_box PF00643.24 OWF41236.1 - 5.7 7.2 7.9 3 8.1 4.4 2.5 2 1 0 2 2 2 0 B-box zinc finger zf-CCHC_6 PF15288.6 OWF41237.1 - 0.0031 17.3 0.5 0.0077 16.1 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle PI3K_P85_iSH2 PF16454.5 OWF41238.1 - 0.018 14.7 0.7 0.026 14.1 0.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Rpr2 PF04032.16 OWF41238.1 - 0.13 12.5 1.0 0.26 11.6 1.0 1.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1282 PF06930.12 OWF41238.1 - 0.2 11.4 6.9 0.055 13.3 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) GPDPase_memb PF10110.9 OWF41238.1 - 0.45 9.2 11.2 0.022 13.6 5.0 1.8 1 1 1 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF1345 PF07077.11 OWF41238.1 - 2.8 7.6 9.7 14 5.3 9.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) BD_b_sandwich PF18820.1 OWF41239.1 - 8.7e-05 22.5 9.7 1.1 9.2 0.3 5.2 1 1 3 5 5 5 3 Bdellovibrio Beta-sandwich SipA_VBS PF17985.1 OWF41239.1 - 0.00019 21.1 1.7 89 3.3 0.0 6.8 8 0 0 8 8 8 0 SipA vinculin binding site Rib PF08428.10 OWF41239.1 - 0.02 14.8 20.1 13 5.8 5.3 5.8 4 1 1 5 5 5 0 Rib/alpha-like repeat PEP-utilizers PF00391.23 OWF41239.1 - 0.2 11.4 3.4 5.5 6.8 0.1 3.4 1 1 1 3 3 3 0 PEP-utilising enzyme, mobile domain Herpes_LMP1 PF05297.11 OWF41239.1 - 0.38 9.9 6.5 1.3 8.2 1.8 2.2 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) ASFV_J13L PF05568.11 OWF41239.1 - 9.3 6.0 19.6 5.9 6.6 0.3 3.6 1 1 3 4 4 4 0 African swine fever virus J13L protein SAM_1 PF00536.30 OWF41241.1 - 3.3e-15 56.3 0.0 7.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF41241.1 - 1.7e-06 28.0 0.0 3.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Anp1 PF03452.14 OWF41242.1 - 1.3e-05 24.8 0.5 0.072 12.5 0.1 3.2 2 1 1 3 3 3 2 Anp1 2OG-FeII_Oxy_3 PF13640.6 OWF41242.1 - 4.8e-05 24.2 0.1 0.00015 22.6 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_1 PF01979.20 OWF41243.1 - 1.4e-34 119.9 0.0 1.8e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OWF41243.1 - 4.3e-14 52.9 1.9 7.5e-08 32.3 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family ASC PF00858.24 OWF41244.1 - 1.9e-98 330.4 6.4 1.7e-79 267.9 3.4 2.3 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel NuiA PF07924.11 OWF41244.1 - 0.1 13.0 0.9 0.39 11.1 0.2 2.3 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein HALZ PF02183.18 OWF41245.1 - 0.067 13.4 26.8 0.053 13.7 2.8 5.2 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF948 PF06103.11 OWF41245.1 - 2.7 8.3 6.5 12 6.2 0.7 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Dynamin_N PF00350.23 OWF41246.1 - 4.9e-38 130.8 2.5 2.2e-37 128.7 0.1 2.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF41246.1 - 1.6e-05 24.9 0.0 0.00022 21.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF41246.1 - 0.00087 18.8 0.2 0.07 12.7 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF1593 PF07632.11 OWF41246.1 - 0.0081 15.6 4.4 0.013 15.0 0.3 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1593) AAA_16 PF13191.6 OWF41246.1 - 0.027 14.9 0.1 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 OWF41246.1 - 0.029 14.2 0.2 1.2 8.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 OWF41246.1 - 0.039 14.2 0.3 1.2 9.4 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TPR_18 PF13512.6 OWF41246.1 - 0.048 13.8 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_TAC_8 PF10666.9 OWF41246.1 - 0.63 10.3 6.1 0.21 11.9 2.1 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 AAA_15 PF13175.6 OWF41246.1 - 0.69 9.5 0.0 0.69 9.5 0.0 4.4 2 2 2 4 4 3 0 AAA ATPase domain SlyX PF04102.12 OWF41246.1 - 2.7 8.7 9.3 0.29 11.8 2.5 3.0 3 0 0 3 3 3 0 SlyX Ssl1 PF04056.14 OWF41247.1 - 8.2e-89 296.5 0.0 1.1e-88 296.1 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 OWF41247.1 - 2.7e-14 53.7 0.0 4.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 OWF41247.1 - 1.5e-13 50.7 29.1 1.5e-12 47.6 15.7 3.2 2 1 0 2 2 2 2 TFIIH C1-like domain VWA PF00092.28 OWF41247.1 - 1.7e-07 31.6 0.0 2.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Condensation PF00668.20 OWF41248.1 - 2.9e-08 32.8 1.4 7.9e-08 31.4 1.4 1.7 1 1 0 1 1 1 1 Condensation domain E1-E2_ATPase PF00122.20 OWF41249.1 - 1.2e-36 125.9 0.0 2.6e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OWF41249.1 - 8.7e-18 65.4 0.0 6.4e-07 29.9 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OWF41249.1 - 1.2e-06 28.1 0.0 3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OWF41249.1 - 2.7e-06 27.4 0.0 6.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 OWF41249.1 - 0.00065 19.5 2.0 0.00065 19.5 2.0 2.2 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus P5-ATPase PF12409.8 OWF41249.1 - 0.0059 16.7 0.1 0.018 15.2 0.1 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_3 PF08282.12 OWF41249.1 - 0.19 11.4 0.1 5.2 6.7 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ICMT PF04140.14 OWF41250.1 - 1.5e-29 102.3 0.8 1.5e-29 102.3 0.8 2.4 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OWF41250.1 - 3.6e-11 43.4 3.2 3.6e-11 43.4 3.2 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OWF41250.1 - 0.0028 17.2 0.6 0.0028 17.2 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) SpoVAB PF13782.6 OWF41250.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.2 2 1 0 2 2 2 0 Stage V sporulation protein AB Exo84_C PF16528.5 OWF41251.1 - 1.8e-54 184.7 0.3 5.7e-54 183.1 0.0 2.0 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OWF41251.1 - 4.1e-14 52.4 0.3 1.2e-13 50.9 0.3 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 OWF41251.1 - 0.015 14.0 4.4 0.032 12.9 0.1 2.8 3 0 0 3 3 3 0 Dor1-like family CIDE-N PF02017.15 OWF41252.1 - 6.4e-30 103.0 0.0 1.2e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 CIDE-N domain DFF-C PF09033.10 OWF41252.1 - 1e-12 48.3 0.1 1.5e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain KHA PF11834.8 OWF41252.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Lectin_C PF00059.21 OWF41253.1 - 0.00019 22.1 0.0 0.00029 21.5 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain 7tm_2 PF00002.24 OWF41254.1 - 8e-07 28.6 9.1 1.2e-06 28.0 9.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ocular_alb PF02101.15 OWF41254.1 - 0.0044 16.0 2.3 0.0069 15.4 2.3 1.3 1 0 0 1 1 1 1 Ocular albinism type 1 protein K1 PF02960.14 OWF41254.1 - 0.0098 16.0 0.2 0.022 14.8 0.2 1.6 1 0 0 1 1 1 1 K1 glycoprotein fn3 PF00041.21 OWF41255.1 - 4.2e-05 23.8 0.5 0.45 10.9 0.0 2.8 2 1 0 2 2 2 2 Fibronectin type III domain fn3_2 PF16893.5 OWF41255.1 - 9e-05 22.5 0.4 0.0025 17.9 0.1 2.5 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF41255.1 - 9.2e-05 22.9 0.1 0.64 10.6 0.0 2.4 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Arylsulfotran_N PF17425.2 OWF41255.1 - 0.0016 18.4 0.9 0.44 10.6 0.1 2.5 2 0 0 2 2 2 2 Arylsulfotransferase Ig-like domain Big_5 PF13205.6 OWF41255.1 - 0.0055 17.4 3.0 0.08 13.6 0.3 2.5 2 0 0 2 2 2 1 Bacterial Ig-like domain CD34_antigen PF06365.12 OWF41255.1 - 0.025 14.2 1.5 0.039 13.5 0.2 2.0 2 1 0 2 2 2 0 CD34/Podocalyxin family DUF1410 PF07198.11 OWF41255.1 - 0.026 15.0 4.1 2.9 8.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1410) TMEM154 PF15102.6 OWF41255.1 - 0.029 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 OWF41255.1 - 0.032 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 OWF41255.1 - 0.1 12.4 0.2 0.22 11.3 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) C2 PF00168.30 OWF41256.1 - 8.3e-28 96.7 0.8 5.8e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 OWF41256.1 - 3.3e-05 23.8 0.0 0.41 10.6 0.0 2.7 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 OWF41256.1 - 0.011 15.3 0.0 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain TIR PF01582.20 OWF41257.1 - 2.9e-15 56.5 0.0 5.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF41257.1 - 2.2e-14 54.1 0.0 4.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF41257.1 - 6e-05 22.7 2.3 0.00028 20.6 1.7 2.3 1 1 1 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OWF41257.1 - 0.0085 16.5 3.1 0.1 13.0 0.6 3.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) DUF1863 PF08937.11 OWF41257.1 - 0.053 13.8 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) CathepsinC_exc PF08773.11 OWF41257.1 - 0.24 11.7 2.8 2.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Cathepsin C exclusion domain LRR_1 PF00560.33 OWF41257.1 - 8.1 7.4 7.6 15 6.6 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Ank_2 PF12796.7 OWF41258.1 - 2.4e-34 117.8 9.2 4.6e-10 39.9 0.1 4.9 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 OWF41258.1 - 2.9e-29 100.2 18.9 2.2e-06 27.8 0.2 9.1 8 1 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 OWF41258.1 - 1.4e-27 95.7 2.6 1.2e-05 25.7 0.1 5.9 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF41258.1 - 2.1e-25 88.4 9.1 1.8e-06 28.1 0.1 6.7 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41258.1 - 9.3e-23 77.9 1.2 0.008 16.6 0.1 9.8 10 0 0 10 10 10 3 Ankyrin repeat SH3_15 PF18346.1 OWF41258.1 - 5.3e-16 58.7 0.5 1.5e-15 57.3 0.5 1.8 1 0 0 1 1 1 1 Mind bomb SH3 repeat domain zf-C3HC4_3 PF13920.6 OWF41258.1 - 1.5e-05 24.8 10.0 1.5e-05 24.8 10.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41258.1 - 0.0016 18.2 9.1 0.0037 17.1 9.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 dCMP_cyt_deam_1 PF00383.23 OWF41258.1 - 3.4 7.6 7.7 9.1 6.2 7.7 1.7 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region MIB_HERC2 PF06701.13 OWF41259.1 - 1.4e-30 105.3 9.0 1.3e-17 63.7 4.3 2.3 2 0 0 2 2 2 2 Mib_herc2 eIF-5a PF01287.20 OWF41260.1 - 3.6e-16 59.0 0.5 5.5e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RPE65 PF03055.15 OWF41261.1 - 1e-73 249.1 0.3 1.2e-73 248.9 0.3 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 OWF41262.1 - 4.9e-34 118.3 0.0 5.5e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF4785 PF16024.5 OWF41262.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) Reeler PF02014.16 OWF41263.1 - 5.4e-18 66.0 0.1 9.7e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Reeler domain LSM PF01423.22 OWF41264.1 - 4.1e-11 42.4 0.0 4.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF3303 PF11746.8 OWF41264.1 - 0.19 12.0 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3303) Cyt-b5 PF00173.28 OWF41265.1 - 8.6e-10 38.6 0.0 2.2e-09 37.3 0.0 1.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Rad60-SLD PF11976.8 OWF41265.1 - 0.035 13.9 0.8 0.097 12.5 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like adh_short PF00106.25 OWF41266.1 - 2.8e-39 134.6 0.0 3.5e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF41266.1 - 5e-23 81.9 0.0 6.9e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF41266.1 - 8.4e-17 61.7 0.1 1.2e-16 61.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OWF41266.1 - 0.012 15.9 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OWF41266.1 - 0.023 13.8 0.1 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aminotran_5 PF00266.19 OWF41267.1 - 3.7e-53 180.8 0.3 5.3e-52 177.0 0.3 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Fib_alpha PF08702.10 OWF41267.1 - 0.17 12.1 0.5 0.52 10.5 0.0 2.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Alg14 PF08660.11 OWF41268.1 - 0.01 15.7 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Ank_2 PF12796.7 OWF41270.1 - 1.8e-12 47.7 0.0 1.6e-05 25.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF41270.1 - 7.7e-10 38.8 0.1 4.2e-05 23.7 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41270.1 - 1.5e-09 37.3 0.1 0.024 15.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OWF41270.1 - 2.3e-08 34.4 0.1 0.023 15.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF41270.1 - 6.4e-05 23.2 0.8 0.041 14.3 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat F-box-like PF12937.7 OWF41271.1 - 2.1e-16 59.5 2.0 6.9e-16 57.9 2.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF41271.1 - 3.4e-11 42.7 2.8 3.4e-11 42.7 2.8 3.2 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.6 OWF41271.1 - 1.2e-06 28.2 10.7 0.0017 18.1 0.8 3.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OWF41271.1 - 1.6e-06 28.4 15.5 0.0023 18.3 1.1 4.5 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF41271.1 - 0.029 14.4 12.3 2.8 8.2 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OWF41271.1 - 0.16 12.6 0.5 0.16 12.6 0.5 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat Beta-lactamase PF00144.24 OWF41272.1 - 6e-54 183.5 0.0 3.3e-53 181.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OWF41272.1 - 0.00026 20.5 0.8 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 OWF41272.1 - 0.084 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase enzyme family Antistasin PF02822.14 OWF41273.1 - 5.4e-05 23.7 10.2 5.4e-05 23.7 10.2 10.9 8 7 0 8 8 8 4 Antistasin family DEPP PF15343.6 OWF41274.1 - 0.0082 16.2 6.1 13 5.8 0.0 5.0 4 2 2 6 6 6 3 Decidual protein induced by progesterone family Rubredoxin PF00301.20 OWF41274.1 - 0.21 11.7 3.7 24 5.1 0.2 3.8 3 0 0 3 3 3 0 Rubredoxin PRIMA1 PF16101.5 OWF41275.1 - 1.8 8.6 5.8 4.4 7.4 5.8 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 BTB PF00651.31 OWF41276.1 - 3.6e-28 98.0 1.3 6e-27 94.1 0.2 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF41276.1 - 7.3e-09 35.7 0.1 8.4e-08 32.3 0.1 2.5 1 1 1 2 2 2 1 BTB And C-terminal Kelch CTD PF12815.7 OWF41277.1 - 0.019 15.5 44.4 0.33 11.6 13.4 3.5 1 1 2 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 HLH PF00010.26 OWF41278.1 - 0.0047 16.9 4.3 11 6.0 0.1 4.6 4 1 1 5 5 5 1 Helix-loop-helix DNA-binding domain DUF1722 PF08349.11 OWF41278.1 - 0.033 14.5 14.5 7.5 6.9 2.2 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1722) F-box-like PF12937.7 OWF41278.1 - 0.059 13.3 15.1 1.8e+04 -7.2 15.1 6.4 1 1 0 1 1 1 0 F-box-like DUF1056 PF06341.11 OWF41278.1 - 0.45 10.9 4.4 32 4.9 0.1 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1056) FERM_N PF09379.10 OWF41278.1 - 0.6 10.1 6.0 27 4.8 0.1 3.9 1 1 4 5 5 5 0 FERM N-terminal domain TFB6 PF17110.5 OWF41278.1 - 1.1 8.9 4.9 1.3e+02 2.3 4.9 2.8 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SVM_signal PF12113.8 OWF41278.1 - 5.1 7.1 15.2 37 4.3 0.4 5.1 3 2 2 5 5 5 0 SVM protein signal sequence MIF4G_like_2 PF09090.11 OWF41278.1 - 5.2 6.5 8.2 27 4.1 8.2 2.5 1 1 0 1 1 1 0 MIF4G like DUF658 PF04936.12 OWF41278.1 - 6 6.6 7.5 16 5.2 3.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF658) Cadherin PF00028.17 OWF41279.1 - 3.3e-93 306.3 24.4 8.7e-17 61.4 0.3 7.4 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF41279.1 - 2.1e-11 43.5 2.2 1.7e-06 27.8 0.0 5.6 6 0 0 6 6 6 2 Cadherin-like RET_CLD1 PF17756.1 OWF41279.1 - 0.0002 21.6 0.1 0.25 11.6 0.0 4.1 4 0 0 4 4 4 1 RET Cadherin like domain 1 TMEM154 PF15102.6 OWF41279.1 - 0.0031 17.4 0.3 0.014 15.3 0.3 2.1 1 0 0 1 1 1 1 TMEM154 protein family DUF4577 PF15145.6 OWF41279.1 - 0.016 15.3 0.2 0.055 13.5 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) EphA2_TM PF14575.6 OWF41279.1 - 0.016 16.0 0.0 0.058 14.3 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OWF41279.1 - 0.019 14.9 0.4 0.039 13.8 0.4 1.5 1 0 0 1 1 1 0 Rifin Pilin_N PF07790.11 OWF41279.1 - 0.042 14.8 0.5 4.8 8.2 0.0 3.9 4 0 0 4 4 3 0 Archaeal Type IV pilin, N-terminal 7TM_GPCR_Srab PF10292.9 OWF41279.1 - 0.042 12.8 0.1 0.069 12.1 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Cadherin_3 PF16184.5 OWF41279.1 - 0.054 13.5 0.1 0.054 13.5 0.1 5.1 6 0 0 6 6 6 0 Cadherin-like SIT PF15330.6 OWF41279.1 - 0.085 13.3 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Cadherin PF00028.17 OWF41280.1 - 6.7e-91 298.9 19.1 1.2e-19 70.5 0.0 8.0 8 0 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 OWF41280.1 - 1.5e-11 44.0 6.1 8.9e-11 41.5 0.1 5.1 8 0 0 8 8 8 1 Cadherin-like Cadherin_3 PF16184.5 OWF41280.1 - 0.0022 17.9 17.5 0.28 11.2 0.3 6.2 7 0 0 7 7 7 2 Cadherin-like Sigma_reg_N PF13800.6 OWF41280.1 - 0.0086 16.3 1.2 0.029 14.6 0.1 2.5 2 0 0 2 2 2 1 Sigma factor regulator N-terminal DUF807 PF05660.11 OWF41280.1 - 0.049 13.6 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) DUF4384 PF14326.6 OWF41280.1 - 0.088 12.9 0.0 0.72 10.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) Na_Ca_ex PF01699.24 OWF41281.1 - 1.8e-19 70.2 33.2 2.6e-15 56.7 14.6 4.2 4 1 1 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 OWF41281.1 - 3e-17 63.0 16.6 3e-17 63.0 16.6 5.4 4 0 0 4 4 4 2 Inner membrane component domain MiAMP1 PF09117.10 OWF41282.1 - 2.4e-09 37.3 62.7 30 4.9 1.3 17.1 1 1 22 23 23 23 23 MiAMP1 Toxin_29 PF08116.11 OWF41282.1 - 6.6e-08 32.4 85.4 70 3.6 0.1 23.9 1 1 38 39 39 39 37 PhTx neurotoxin family Neur_chan_LBD PF02931.23 OWF41283.1 - 1.3e-46 158.8 0.0 1.9e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41283.1 - 7.6e-43 147.3 3.4 2.5e-42 145.6 3.4 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Cu-oxidase_3 PF07732.15 OWF41284.1 - 6.4e-44 148.8 1.8 1.7e-42 144.2 0.7 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF41284.1 - 3.7e-32 110.9 4.8 1.8e-28 99.0 0.3 3.8 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF41284.1 - 5.2e-22 78.7 0.2 1e-20 74.5 0.1 3.0 2 1 0 2 2 2 1 Multicopper oxidase CHB_HEX_C_1 PF13290.6 OWF41284.1 - 0.043 13.8 0.0 1 9.4 0.0 2.9 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Cu-oxidase_3 PF07732.15 OWF41285.1 - 4.7e-37 126.6 1.2 4.7e-37 126.6 1.2 4.0 4 1 1 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF41285.1 - 4.6e-33 113.9 4.0 7.8e-29 100.2 0.3 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 OWF41285.1 - 1.7e-25 90.0 0.5 1.7e-25 90.0 0.5 2.8 3 1 0 3 3 3 1 Multicopper oxidase E1_DerP2_DerF2 PF02221.15 OWF41286.1 - 1.6e-17 64.2 0.1 2.2e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 ML domain TMEM144 PF07857.12 OWF41287.1 - 2.4e-107 358.8 12.5 3.3e-107 358.3 12.5 1.2 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 OWF41287.1 - 2.7e-07 30.2 19.5 5.8e-07 29.1 6.9 3.0 2 1 1 3 3 3 2 Sugar transport protein Multi_Drug_Res PF00893.19 OWF41287.1 - 0.18 12.5 6.4 0.16 12.6 3.6 2.4 2 0 0 2 2 2 0 Small Multidrug Resistance protein Maff2 PF12750.7 OWF41287.1 - 0.35 10.7 5.8 0.11 12.3 1.2 2.4 2 0 0 2 2 2 0 Maff2 family Aim19 PF10315.9 OWF41287.1 - 3.3 8.0 7.5 9.1 6.6 0.7 3.3 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 19 PPR_3 PF13812.6 OWF41288.1 - 0.00023 21.2 2.4 0.31 11.1 0.1 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain DUF4363 PF14276.6 OWF41288.1 - 0.0016 18.5 4.6 0.02 15.0 1.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4363) PPR PF01535.20 OWF41288.1 - 0.005 17.0 11.7 1.8 9.0 0.2 6.5 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 OWF41288.1 - 0.015 14.7 0.4 0.073 12.4 0.2 2.2 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TelA PF05816.11 OWF41288.1 - 0.018 14.1 3.6 0.082 12.0 0.8 2.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) PPR_2 PF13041.6 OWF41288.1 - 0.021 15.0 8.8 16 5.8 0.2 5.9 5 1 0 5 5 5 0 PPR repeat family Erf4 PF10256.9 OWF41288.1 - 0.027 14.6 1.0 3.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Pre-PUA PF17832.1 OWF41290.1 - 2e-22 79.7 0.1 3.6e-22 78.8 0.1 1.5 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 OWF41290.1 - 1e-19 70.2 1.2 1.5e-19 69.7 0.3 1.7 2 0 0 2 2 2 1 PUA domain zf-C2H2 PF00096.26 OWF41291.1 - 0.0014 18.9 16.1 0.0027 18.1 3.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF41291.1 - 0.017 15.5 3.1 3.2 8.3 0.5 3.1 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.13 OWF41291.1 - 0.15 12.1 1.5 0.5 10.5 1.5 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PHD PF00628.29 OWF41291.1 - 0.31 11.0 4.8 0.11 12.4 1.5 2.0 2 0 0 2 2 2 0 PHD-finger zf-C2H2_4 PF13894.6 OWF41291.1 - 0.76 10.8 21.2 0.097 13.6 2.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger FYVE PF01363.21 OWF41291.1 - 2 8.6 8.1 9.4 6.5 7.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_11 PF16622.5 OWF41291.1 - 7.3 6.5 11.1 1.1 9.1 1.5 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type V-set PF07686.17 OWF41292.1 - 2e-06 28.0 0.1 3.9e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 OWF41292.1 - 0.0014 19.2 0.2 0.0027 18.3 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF41292.1 - 0.043 13.9 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 OWF41292.1 - 0.063 13.5 0.2 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 Immunoglobulin domain ECF_trnsprt PF12822.7 OWF41293.1 - 0.0004 20.5 0.6 0.00059 20.0 0.6 1.2 1 0 0 1 1 1 1 ECF transporter, substrate-specific component DMT_YdcZ PF04657.13 OWF41293.1 - 0.005 17.1 0.7 0.0095 16.2 0.7 1.4 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ ATP-synt_S1 PF05827.12 OWF41293.1 - 0.071 12.9 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) ubiquitin PF00240.23 OWF41294.1 - 5.5e-06 26.0 0.1 1.8e-05 24.4 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin family RRM_1 PF00076.22 OWF41294.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 OWF41294.1 - 0.0066 16.5 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat DrrA_P4M PF14860.6 OWF41294.1 - 0.007 16.2 1.6 0.04 13.8 1.6 2.4 1 0 0 1 1 1 1 DrrA phosphatidylinositol 4-phosphate binding domain TPR_8 PF13181.6 OWF41294.1 - 0.014 15.5 0.0 0.058 13.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF41294.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat RSN1_TM PF13967.6 OWF41294.1 - 0.07 12.9 0.1 1.8 8.3 0.0 3.0 3 0 0 3 3 3 0 Late exocytosis, associated with Golgi transport SAM_3 PF18016.1 OWF41294.1 - 0.07 13.0 0.3 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) MIEAP PF16026.5 OWF41295.1 - 9.6e-29 101.0 4.1 9.8e-29 101.0 0.4 2.4 2 1 0 2 2 2 1 Mitochondria-eating protein TMF_DNA_bd PF12329.8 OWF41295.1 - 0.00012 22.0 5.2 0.00012 22.0 5.2 1.9 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 OWF41295.1 - 0.016 15.3 11.3 0.024 14.7 6.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor TetR_C_13 PF16925.5 OWF41295.1 - 0.037 13.9 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BRE1 PF08647.11 OWF41295.1 - 0.041 13.9 7.3 3.1 7.9 0.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 OWF41295.1 - 0.065 12.5 3.5 0.15 11.4 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3053 PF11254.8 OWF41295.1 - 0.076 12.6 1.1 0.1 12.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) GAS PF13851.6 OWF41295.1 - 0.11 11.9 9.7 0.074 12.4 4.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.12 OWF41295.1 - 0.13 12.5 5.7 3.3 8.0 0.7 3.5 4 1 0 4 4 3 0 Proteins of 100 residues with WXG CemA PF03040.14 OWF41295.1 - 0.2 11.6 0.6 0.35 10.8 0.3 1.5 1 1 0 1 1 1 0 CemA family APG6_N PF17675.1 OWF41295.1 - 0.22 12.1 9.6 0.078 13.5 4.7 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF2046 PF09755.9 OWF41295.1 - 0.23 10.6 8.4 0.93 8.7 6.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DivIC PF04977.15 OWF41295.1 - 0.46 10.3 7.8 0.04 13.7 3.0 1.7 2 0 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.19 OWF41295.1 - 0.5 8.2 6.5 0.15 10.0 0.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4355 PF14265.6 OWF41295.1 - 0.62 10.3 10.1 0.035 14.3 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF5595 PF18077.1 OWF41295.1 - 2.1 8.5 8.9 2.7 8.1 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) Mto2_bdg PF12808.7 OWF41295.1 - 3.4 8.0 9.0 0.9 9.9 4.9 2.2 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Tho2 PF11262.8 OWF41295.1 - 5.2 6.2 7.8 5.7 6.1 3.0 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 YabA PF06156.13 OWF41295.1 - 6.5 7.5 8.9 6 7.6 4.5 2.3 2 1 0 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 OWF41295.1 - 7.8 6.5 9.6 12 5.9 9.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MIEAP PF16026.5 OWF41296.1 - 4.4e-32 111.9 0.0 4.4e-32 111.9 0.0 3.2 2 1 1 3 3 1 1 Mitochondria-eating protein UPF0242 PF06785.11 OWF41296.1 - 0.00013 22.1 73.3 0.0025 17.9 32.8 3.6 1 1 2 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 OWF41296.1 - 0.0002 21.2 25.6 0.0002 21.2 25.6 4.4 3 1 1 4 4 4 2 Domain of unknown function (DUF4201) GAS PF13851.6 OWF41296.1 - 0.0031 16.9 75.9 0.02 14.3 11.3 4.6 3 2 1 4 4 4 3 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 OWF41296.1 - 0.0069 16.6 62.7 0.054 13.7 7.4 4.2 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OWF41296.1 - 0.013 14.4 60.9 0.024 13.6 6.0 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein Csm1_N PF18504.1 OWF41296.1 - 0.021 15.2 3.9 0.021 15.2 3.9 7.0 2 2 5 7 7 6 0 Csm1 N-terminal domain DUF5595 PF18077.1 OWF41296.1 - 0.11 12.6 0.3 0.11 12.6 0.3 6.5 4 2 1 5 5 4 0 Domain of unknown function (DUF5595) Fez1 PF06818.15 OWF41296.1 - 0.51 10.8 62.6 3.4 8.1 12.2 3.9 2 1 2 4 4 4 0 Fez1 DUF2046 PF09755.9 OWF41296.1 - 0.66 9.2 56.3 1.9 7.7 24.9 4.5 1 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) DivIC PF04977.15 OWF41296.1 - 0.78 9.5 59.7 1.9 8.3 9.1 6.8 3 2 4 7 7 7 0 Septum formation initiator CCDC92 PF14916.6 OWF41296.1 - 0.85 9.4 0.0 0.85 9.4 0.0 7.3 7 1 0 7 7 6 0 Coiled-coil domain of unknown function DUF812 PF05667.11 OWF41296.1 - 1.5 7.6 63.6 0.17 10.7 10.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 OWF41296.1 - 1.5 8.8 67.5 0.29 11.1 29.1 4.6 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 OWF41296.1 - 1.6 7.7 59.4 0.45 9.6 41.6 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 OWF41296.1 - 1.7 8.4 66.2 0.62 9.9 37.6 4.4 4 1 1 5 5 5 0 Coiled-coil region of CCDC155 or KASH MAD PF05557.13 OWF41296.1 - 4.3 5.6 62.9 1.1 7.5 29.0 3.0 1 1 1 3 3 3 0 Mitotic checkpoint protein ERM PF00769.19 OWF41296.1 - 4.4 7.0 66.2 3.6 7.3 35.4 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cluap1 PF10234.9 OWF41296.1 - 6.1 6.2 59.5 0.28 10.5 5.1 4.7 2 1 3 5 5 5 0 Clusterin-associated protein-1 DUF4407 PF14362.6 OWF41296.1 - 6.9 5.9 52.9 0.69 9.2 12.6 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) ADIP PF11559.8 OWF41296.1 - 7.3 6.7 66.9 2.6 8.1 8.3 5.3 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 OWF41296.1 - 9.8 6.9 58.6 0.29 11.8 11.1 5.8 4 1 3 7 7 6 0 Initiation control protein YabA MIEAP PF16026.5 OWF41297.1 - 6.1e-33 114.7 1.7 4.5e-20 72.7 0.0 4.0 3 2 1 5 5 5 2 Mitochondria-eating protein BBP1_C PF15272.6 OWF41297.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.8 2 1 3 5 5 5 0 Spindle pole body component BBP1, C-terminal DUF4810 PF16068.5 OWF41297.1 - 0.13 12.8 4.7 0.26 11.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) DUF4407 PF14362.6 OWF41297.1 - 3.2 7.0 9.8 12 5.2 9.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sulfotransfer_1 PF00685.27 OWF41298.1 - 6.9e-06 25.7 3.4 4.5e-05 23.1 1.2 2.3 1 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF41298.1 - 0.017 15.5 0.4 0.082 13.3 0.2 2.1 2 0 0 2 2 2 0 Sulfotransferase family Neur_chan_LBD PF02931.23 OWF41299.1 - 8e-45 152.9 0.0 1.2e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41299.1 - 3.4e-35 122.2 0.8 6.5e-30 104.9 0.1 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF5639 PF18690.1 OWF41299.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5639) DUF3908 PF13048.6 OWF41299.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) Pkinase PF00069.25 OWF41301.1 - 0.00016 21.1 0.0 0.16 11.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.25 OWF41304.1 - 1.1e-14 54.5 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41304.1 - 0.0032 16.8 0.0 0.0068 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF934 PF06073.12 OWF41304.1 - 0.035 14.0 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) Creb_binding PF09030.10 OWF41304.1 - 0.037 14.7 0.1 0.13 13.0 0.1 1.9 1 0 0 1 1 1 0 Creb binding UCH PF00443.29 OWF41305.1 - 1.7e-34 119.5 4.9 1.7e-33 116.2 4.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF41305.1 - 2.4e-07 30.7 9.7 0.00019 21.1 9.7 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mid2 PF04478.12 OWF41305.1 - 0.0047 16.8 0.4 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Ldl_recept_b PF00058.17 OWF41306.1 - 7.8e-19 67.9 4.0 1.4e-07 31.9 0.2 4.7 4 0 0 4 4 4 4 Low-density lipoprotein receptor repeat class B SRCR PF00530.18 OWF41306.1 - 1.7e-15 57.3 0.6 2.9e-15 56.6 0.6 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF5050 PF16472.5 OWF41306.1 - 0.00067 19.0 0.0 0.0051 16.1 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) SRCR_2 PF15494.6 OWF41306.1 - 0.0015 19.0 0.2 0.0032 18.0 0.2 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF41306.1 - 0.11 13.1 0.6 0.2 12.2 0.6 1.4 1 0 0 1 1 1 0 Hepsin, SRCR domain NHL PF01436.21 OWF41307.1 - 4.2e-14 51.7 3.0 6.7e-05 22.7 0.0 4.8 5 0 0 5 5 5 2 NHL repeat zf-RING_UBOX PF13445.6 OWF41307.1 - 2.8e-10 40.1 3.5 2.8e-10 40.1 3.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF41307.1 - 1.4e-09 37.7 6.2 1.4e-09 37.7 6.2 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF5128 PF17170.4 OWF41307.1 - 2.5e-07 30.2 2.2 0.012 14.8 0.0 3.4 3 1 0 4 4 4 3 6-bladed beta-propeller zf-C3HC4_3 PF13920.6 OWF41307.1 - 4e-07 29.8 4.7 4e-07 29.8 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF41307.1 - 8.8e-07 29.2 6.8 8.8e-07 29.2 6.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF41307.1 - 4.8e-06 26.4 7.4 4.8e-06 26.4 7.4 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF41307.1 - 9.9e-06 25.3 7.8 0.0003 20.6 8.7 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF41307.1 - 0.00018 21.6 9.2 0.00018 21.6 9.2 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF41307.1 - 0.0031 17.4 5.0 0.0031 17.4 5.0 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 DUF4934 PF16288.5 OWF41307.1 - 0.0039 17.1 0.3 0.96 9.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4934) SGL PF08450.12 OWF41307.1 - 0.016 14.8 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region TolB_like PF15869.5 OWF41307.1 - 0.084 12.1 1.1 8 5.6 0.0 3.3 2 2 1 3 3 3 0 TolB-like 6-blade propeller-like tRNA_bind PF01588.20 OWF41308.1 - 1.6e-31 108.3 1.7 2.3e-31 107.8 0.8 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain YabA PF06156.13 OWF41308.1 - 0.51 11.0 4.2 1.5 9.5 4.2 1.8 1 1 0 1 1 1 0 Initiation control protein YabA GAGA_bind PF06217.12 OWF41308.1 - 3.9 7.7 8.3 5.4 7.2 8.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family V_ATPase_I PF01496.19 OWF41308.1 - 4.1 5.2 5.3 5.1 4.9 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family E1_DerP2_DerF2 PF02221.15 OWF41309.1 - 2e-19 70.4 0.5 2.7e-19 69.9 0.5 1.2 1 0 0 1 1 1 1 ML domain 7tm_1 PF00001.21 OWF41311.1 - 1.1e-34 119.9 9.8 1.6e-34 119.5 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 OWF41311.1 - 0.037 14.3 4.4 3.8 7.9 0.2 3.3 3 0 0 3 3 3 0 Orf78 (ac78) DUF3899 PF13038.6 OWF41311.1 - 0.15 12.6 4.8 1.1 9.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Macoilin PF09726.9 OWF41311.1 - 0.53 8.8 4.0 0.7 8.4 4.0 1.1 1 0 0 1 1 1 0 Macoilin family OAD_gamma PF04277.13 OWF41311.1 - 3.4 8.3 0.0 3.4 8.3 0.0 3.8 3 1 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF5305 PF17231.2 OWF41311.1 - 4.5 6.6 7.8 2.8 7.3 0.7 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF2572 PF10833.8 OWF41312.1 - 0.017 14.9 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) zf-C3HC4_2 PF13923.6 OWF41314.1 - 2.5e-09 36.8 8.0 2.5e-09 36.8 8.0 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 OWF41314.1 - 6.2e-09 36.4 4.3 6.2e-09 36.4 4.3 3.3 3 0 0 3 3 2 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 OWF41314.1 - 5.7e-08 32.5 7.9 5.7e-08 32.5 7.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF41314.1 - 1.7e-07 31.3 8.9 3.5e-07 30.3 7.8 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF41314.1 - 3.4e-07 30.5 8.4 3.4e-07 30.5 8.4 3.4 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF41314.1 - 8.5e-07 28.9 8.6 8.5e-07 28.9 8.6 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF41314.1 - 1.3e-06 28.2 4.6 1.3e-06 28.2 4.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41314.1 - 0.00059 19.7 7.4 0.00059 19.7 7.4 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF41314.1 - 0.00081 19.6 8.0 0.00081 19.6 8.0 4.1 4 2 0 4 4 3 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OWF41314.1 - 0.0018 18.1 2.3 0.0018 18.1 2.3 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.15 OWF41314.1 - 0.0033 17.6 0.0 0.009 16.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain Sina PF03145.16 OWF41314.1 - 0.0061 16.5 4.6 0.0061 16.5 4.6 2.5 1 1 2 3 3 3 2 Seven in absentia protein family zf-RING_5 PF14634.6 OWF41314.1 - 0.01 15.8 6.3 0.01 15.8 6.3 3.4 2 1 0 2 2 1 0 zinc-RING finger domain Phage_Mu_Gam PF07352.12 OWF41314.1 - 0.086 12.8 4.4 0.14 12.1 4.4 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein PRP1_N PF06424.12 OWF41314.1 - 0.14 12.5 0.9 0.27 11.6 0.9 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal zf-TRAF_2 PF15965.5 OWF41314.1 - 0.48 10.9 18.3 0.85 10.1 2.0 3.6 2 1 2 4 4 4 0 TRAF-like zinc-finger zf-RING_10 PF16685.5 OWF41314.1 - 1 9.5 16.9 0.13 12.4 11.6 2.3 2 1 0 2 2 2 0 zinc RING finger of MSL2 DUF1640 PF07798.11 OWF41314.1 - 1.4 9.0 11.8 1.3 9.0 9.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) BRO1 PF03097.18 OWF41315.1 - 3.2e-84 283.0 0.1 4.1e-84 282.7 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 OWF41315.1 - 2.3e-17 62.9 3.6 4.7e-17 61.9 3.6 1.6 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.24 OWF41315.1 - 1.8e-09 37.8 0.0 4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF41315.1 - 0.00038 20.2 0.0 0.00098 18.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF41315.1 - 0.082 13.2 0.1 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Uds1 PF15456.6 OWF41315.1 - 2.5 8.3 9.1 1.1 9.4 1.0 2.5 2 0 0 2 2 2 0 Up-regulated During Septation AAA PF00004.29 OWF41316.1 - 4.1e-17 62.8 0.0 9.1e-17 61.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OWF41316.1 - 2.7e-09 36.9 2.8 2.9e-08 33.6 0.2 3.2 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 OWF41316.1 - 2.8e-05 23.4 0.0 4.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OWF41316.1 - 0.00014 22.2 0.0 0.00058 20.2 0.0 2.1 2 1 0 2 2 1 1 RNA helicase Rad17 PF03215.15 OWF41316.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OWF41316.1 - 0.00037 20.9 0.0 0.0023 18.3 0.0 2.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 OWF41316.1 - 0.00039 20.2 0.0 0.00092 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 OWF41316.1 - 0.00072 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OWF41316.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 OWF41316.1 - 0.0017 18.6 0.0 0.005 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 OWF41316.1 - 0.0021 18.1 0.0 0.0048 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OWF41316.1 - 0.0024 17.4 0.0 0.0093 15.5 0.0 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 OWF41316.1 - 0.0043 17.6 0.0 0.013 16.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 OWF41316.1 - 0.0046 17.5 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OWF41316.1 - 0.0047 16.7 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 OWF41316.1 - 0.0058 16.4 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OWF41316.1 - 0.0063 16.3 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OWF41316.1 - 0.012 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 OWF41316.1 - 0.016 14.6 0.0 0.1 12.0 0.0 2.3 3 0 0 3 3 2 0 Bacterial TniB protein AAA_14 PF13173.6 OWF41316.1 - 0.019 15.0 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OWF41316.1 - 0.021 14.8 0.0 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OWF41316.1 - 0.021 15.1 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OWF41316.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OWF41316.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 OWF41316.1 - 0.097 12.8 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 OWF41316.1 - 0.1 12.2 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1330 PF07045.11 OWF41317.1 - 7.7e-13 48.6 0.0 1.8e-09 37.8 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) Transketolase_N PF00456.21 OWF41317.1 - 0.018 14.0 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain RTP1_C1 PF10363.9 OWF41318.1 - 1.8e-33 115.1 0.0 1.5e-32 112.1 0.0 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 OWF41318.1 - 3.1e-05 24.5 0.0 0.00017 22.1 0.0 2.3 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OWF41318.1 - 0.00018 21.5 4.0 0.011 16.0 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat PNK3P PF08645.11 OWF41319.1 - 1.4e-52 177.7 1.1 2.5e-52 176.9 0.0 2.0 3 0 0 3 3 3 1 Polynucleotide kinase 3 phosphatase FHA_2 PF17913.1 OWF41319.1 - 2.9e-31 107.6 0.0 6.6e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain AAA_33 PF13671.6 OWF41319.1 - 5.3e-18 65.6 0.0 5.6e-10 39.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 OWF41319.1 - 0.00014 21.4 8.1 0.00052 19.6 0.2 2.6 3 0 0 3 3 3 2 Chromatin associated protein KTI12 Hydrolase_6 PF13344.6 OWF41319.1 - 0.00039 20.5 0.2 0.0031 17.6 0.0 2.7 4 0 0 4 4 4 1 Haloacid dehalogenase-like hydrolase 6PF2K PF01591.18 OWF41319.1 - 0.0018 17.6 0.1 0.15 11.3 0.0 2.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Cyt-b5 PF00173.28 OWF41320.1 - 6.7e-21 74.2 0.1 9.5e-21 73.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain C1q PF00386.21 OWF41321.1 - 2.3e-17 63.4 5.5 3.8e-17 62.7 5.5 1.4 1 0 0 1 1 1 1 C1q domain But2 PF09792.9 OWF41321.1 - 0.029 14.8 0.6 0.049 14.0 0.6 1.4 1 0 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain YvrJ PF12841.7 OWF41321.1 - 0.17 11.4 0.4 0.54 9.8 0.3 1.9 1 1 0 1 1 1 0 YvrJ protein family LRR_8 PF13855.6 OWF41322.1 - 4.4e-24 84.0 45.2 5.4e-10 38.9 9.0 9.0 8 0 0 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OWF41322.1 - 1.7e-12 47.3 47.5 0.11 13.0 0.4 10.7 6 3 3 9 9 9 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 OWF41322.1 - 2.5e-10 41.0 0.1 6.7e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF41322.1 - 2e-05 24.5 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF41322.1 - 0.00011 21.7 6.3 0.027 14.0 0.7 2.8 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OWF41322.1 - 0.055 13.5 27.5 8.9 6.7 0.8 9.7 11 0 0 11 11 11 0 Leucine Rich repeat DUF3149 PF11346.8 OWF41322.1 - 0.1 12.2 0.4 0.29 10.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) LRR_1 PF00560.33 OWF41322.1 - 0.15 12.7 36.0 2.1 9.2 0.2 10.9 12 1 0 12 12 12 0 Leucine Rich Repeat Fibrinogen_BP PF08017.11 OWF41324.1 - 0.0025 16.3 0.0 0.0025 16.3 0.0 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein DUF2345 PF10106.9 OWF41324.1 - 0.99 9.3 7.7 5.8 6.8 1.2 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2345) Ank_2 PF12796.7 OWF41325.1 - 2.4e-22 79.3 1.6 5.9e-08 33.2 0.1 6.9 5 3 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF41325.1 - 5.4e-21 74.7 0.5 1.9e-05 25.1 0.0 8.4 7 3 3 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF41325.1 - 2.3e-19 69.2 0.0 4.6e-06 26.8 0.0 5.3 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41325.1 - 9.3e-15 53.3 0.0 0.0028 18.0 0.0 7.7 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 OWF41325.1 - 1.6e-09 37.7 0.0 5 7.7 0.0 6.9 9 0 0 9 9 9 3 Ankyrin repeat ALS2CR8 PF15299.6 OWF41326.1 - 8.9e-28 97.7 10.4 1.4e-13 51.2 3.6 2.9 3 0 0 3 3 3 2 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Pkinase PF00069.25 OWF41327.1 - 1.6e-64 217.8 0.0 2e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41327.1 - 2.5e-35 122.0 0.0 2.9e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF41327.1 - 0.00015 20.7 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OWF41327.1 - 0.0022 17.0 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OWF41327.1 - 0.0058 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OWF41327.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF41327.1 - 0.039 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_L22 PF00237.19 OWF41328.1 - 4.1e-46 155.4 0.3 5.9e-46 154.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RINGv PF12906.7 OWF41329.1 - 1.9e-14 53.5 8.4 1.9e-14 53.5 8.4 2.7 3 0 0 3 3 3 1 RING-variant domain DUF2593 PF10767.9 OWF41329.1 - 0.16 12.0 0.3 0.27 11.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) RCC1 PF00415.18 OWF41330.1 - 1.7e-54 182.2 32.4 5.5e-10 39.7 0.1 9.4 7 3 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF41330.1 - 6.6e-41 137.3 48.4 1.2e-07 31.4 1.0 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 OWF41330.1 - 0.00013 21.7 0.2 0.34 10.6 0.0 3.8 3 1 0 3 3 3 2 TUP1-like enhancer of split Kelch_5 PF13854.6 OWF41330.1 - 0.52 10.4 7.3 59 3.8 0.0 4.8 5 0 0 5 5 5 0 Kelch motif Hormone_recep PF00104.30 OWF41331.1 - 2e-37 128.8 0.0 3.1e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF41331.1 - 2.2e-30 104.9 16.4 2.2e-30 104.9 16.4 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) DUF5479 PF17575.2 OWF41332.1 - 0.011 16.3 17.6 23 5.6 0.1 6.1 1 1 6 7 7 7 0 Family of unknown function (DUF5479) MlaD PF02470.20 OWF41332.1 - 0.013 15.8 4.4 1.1e+02 3.1 4.4 4.7 1 1 0 1 1 1 0 MlaD protein DUF2732 PF10809.8 OWF41332.1 - 0.13 12.1 1.8 46 4.0 0.1 4.4 1 1 6 8 8 8 0 Protein of unknown function (DUF2732) DUF1071 PF06378.11 OWF41332.1 - 0.15 11.6 17.2 3.7 7.1 1.7 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1071) UvrA_inter PF17760.1 OWF41332.1 - 0.3 11.2 3.4 21 5.2 0.4 3.2 1 1 1 3 3 3 0 UvrA interaction domain SEP PF08059.13 OWF41332.1 - 0.48 11.0 5.0 44 4.7 1.1 3.6 1 1 3 4 4 4 0 SEP domain Defb50 PF17546.2 OWF41332.1 - 6.7 6.7 25.1 1.7e+02 2.2 0.1 9.3 11 1 1 12 12 12 0 Beta defensin 50 RVT_1 PF00078.27 OWF41333.1 - 9.8e-11 41.6 0.2 3.9e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4028 PF13220.6 OWF41333.1 - 0.043 13.6 0.3 0.12 12.1 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) DUF4493 PF14900.6 OWF41333.1 - 0.19 11.5 0.1 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4493) PAE PF03283.13 OWF41334.1 - 5.5e-78 262.6 0.1 8.5e-78 262.0 0.1 1.1 1 0 0 1 1 1 1 Pectinacetylesterase Connexin PF00029.19 OWF41334.1 - 0.029 14.1 4.0 0.043 13.6 4.0 1.2 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 OWF41334.1 - 0.12 11.1 7.3 0.18 10.6 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EMC3_TMCO1 PF01956.16 OWF41334.1 - 0.18 11.5 0.5 0.45 10.2 0.4 1.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CDC45 PF02724.14 OWF41334.1 - 0.25 9.6 9.6 0.33 9.2 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4228 PF14009.6 OWF41334.1 - 0.69 10.3 7.4 1.2 9.5 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SprA-related PF12118.8 OWF41334.1 - 1.4 8.0 5.8 1.9 7.5 5.8 1.2 1 0 0 1 1 1 0 SprA-related family Rrn6 PF10214.9 OWF41334.1 - 1.4 7.3 10.4 2.1 6.7 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 OWF41334.1 - 3.3 6.4 7.7 4.7 5.9 7.7 1.1 1 0 0 1 1 1 0 Presenilin MDFI PF15316.6 OWF41334.1 - 3.3 7.8 4.8 5.6 7.0 4.8 1.3 1 0 0 1 1 1 0 MyoD family inhibitor RR_TM4-6 PF06459.12 OWF41334.1 - 6.3 6.5 10.8 9 6.0 10.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NHL PF01436.21 OWF41335.1 - 0.0061 16.5 0.1 7 6.9 0.0 3.1 3 0 0 3 3 3 2 NHL repeat SH3_15 PF18346.1 OWF41335.1 - 0.024 14.9 0.2 0.19 12.0 0.0 2.4 1 1 1 2 2 2 0 Mind bomb SH3 repeat domain SGL PF08450.12 OWF41335.1 - 0.04 13.5 0.1 0.36 10.4 0.1 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF41335.1 - 0.15 12.4 1.1 1.1e+02 3.5 0.0 4.3 5 0 0 5 5 5 0 Two component regulator propeller Ig_6 PF18452.1 OWF41336.1 - 0.0017 17.9 23.8 9.5 5.9 0.2 8.7 2 2 4 6 6 6 5 Immunoglobulin domain RabGGT_insert PF07711.11 OWF41336.1 - 0.008 16.6 0.0 94 3.6 0.0 4.1 1 1 3 4 4 4 0 Rab geranylgeranyl transferase alpha-subunit, insert domain DUF3976 PF13121.6 OWF41336.1 - 0.022 14.9 29.1 39 4.5 0.3 10.3 10 2 2 12 12 12 0 Domain of unknown function (DUF3976) DUF3976 PF13121.6 OWF41337.1 - 2.3e-06 27.6 33.7 5.8 7.1 1.3 11.3 11 2 1 12 12 12 2 Domain of unknown function (DUF3976) Izumo-Ig PF16706.5 OWF41337.1 - 0.00067 19.7 18.1 15 5.7 0.7 8.3 1 1 7 8 8 8 1 Izumo-like Immunoglobulin domain RabGGT_insert PF07711.11 OWF41337.1 - 0.031 14.7 0.0 52 4.4 0.0 4.0 1 1 3 4 4 4 0 Rab geranylgeranyl transferase alpha-subunit, insert domain Pentapeptide_4 PF13599.6 OWF41337.1 - 0.04 14.1 2.5 17 5.7 0.1 3.9 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Ig_6 PF18452.1 OWF41337.1 - 1.5 8.4 24.9 13 5.4 0.0 8.9 1 1 7 8 8 8 0 Immunoglobulin domain Ig_2 PF13895.6 OWF41337.1 - 1.9 8.9 19.4 1.8e+04 -11.0 19.4 7.2 1 1 0 1 1 1 0 Immunoglobulin domain RRM_1 PF00076.22 OWF41338.1 - 8.7e-12 44.7 0.0 0.00026 20.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF41338.1 - 0.024 14.7 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif RBM39linker PF15519.6 OWF41338.1 - 0.1 13.7 0.1 0.1 13.7 0.1 2.6 3 1 1 4 4 4 0 linker between RRM2 and RRM3 domains in RBM39 protein Vg_Tdu PF07545.14 OWF41339.1 - 1.9e-15 56.3 0.2 3.6e-15 55.4 0.2 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family Vg_Tdu PF07545.14 OWF41340.1 - 2.6e-17 62.3 0.4 4.7e-17 61.4 0.4 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family BIR PF00653.21 OWF41341.1 - 3.5e-29 101.3 7.4 1.2e-18 67.5 0.2 3.9 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF41341.1 - 1.5e-09 37.6 19.7 1.5e-09 37.6 19.7 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41341.1 - 0.32 10.9 18.4 1 9.3 18.4 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 COesterase PF00135.28 OWF41344.1 - 8e-89 298.8 0.0 1.1e-88 298.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF41344.1 - 1.1e-08 35.2 0.0 0.0008 19.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold T2SS-T3SS_pil_N PF13629.6 OWF41344.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Pilus formation protein N terminal region MFS_1 PF07690.16 OWF41345.1 - 4.4e-06 25.9 46.0 0.00041 19.4 16.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF5435 PF17503.2 OWF41345.1 - 0.18 11.5 0.2 0.31 10.7 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Nitrate_red_del PF02613.15 OWF41346.1 - 0.61 10.1 31.8 1.9e+02 2.0 0.0 13.2 8 5 7 16 16 16 0 Nitrate reductase delta subunit SoxD PF04267.12 OWF41347.1 - 0.0019 18.2 11.5 6.2 7.0 0.3 4.6 1 1 4 5 5 5 5 Sarcosine oxidase, delta subunit family CM_1 PF07736.11 OWF41347.1 - 0.6 10.5 11.1 8.4 6.8 0.2 4.5 1 1 4 5 5 5 0 Chorismate mutase type I MRP-63 PF14978.6 OWF41347.1 - 1.3 9.7 13.9 18 6.0 0.5 3.8 1 1 2 3 3 3 0 Mitochondrial ribosome protein 63 TP53IP5 PF15331.6 OWF41347.1 - 6.8 6.8 7.9 7 6.7 2.9 1.6 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 TPH PF13868.6 OWF41349.1 - 8.8e-79 264.6 141.9 8.8e-79 264.6 141.9 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DUF4251 PF14059.6 OWF41349.1 - 0.016 15.2 1.6 2.7 7.9 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) DUF3634 PF12321.8 OWF41349.1 - 5.2 7.5 7.5 0.55 10.6 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) FoP_duplication PF13865.6 OWF41350.1 - 1.1e-17 64.3 17.7 1.1e-17 64.3 17.7 4.4 1 1 3 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Pkinase_Tyr PF07714.17 OWF41351.1 - 9.4e-93 310.2 0.2 2.2e-92 309.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OWF41351.1 - 3.6e-49 167.5 0.7 7.1e-49 166.5 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain SH2 PF00017.24 OWF41351.1 - 3e-13 49.7 0.3 1.5e-12 47.4 0.1 2.4 2 0 0 2 2 2 1 SH2 domain FCH PF00611.23 OWF41351.1 - 4.5e-05 23.6 0.1 4.5e-05 23.6 0.1 3.7 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MOSC PF03473.17 OWF41351.1 - 0.017 15.1 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 MOSC domain GAS PF13851.6 OWF41351.1 - 0.041 13.2 24.3 0.11 11.8 3.4 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 OWF41351.1 - 0.042 13.2 10.2 0.87 8.9 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ELF PF03317.13 OWF41351.1 - 0.13 12.3 1.3 0.49 10.4 0.0 2.6 3 0 0 3 3 2 0 ELF protein Spc7 PF08317.11 OWF41351.1 - 0.15 10.9 20.8 0.065 12.1 1.3 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 OWF41351.1 - 1.2 7.7 12.0 0.77 8.3 5.0 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 OWF41351.1 - 1.4 9.2 20.2 2.4 8.5 0.8 3.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 OWF41351.1 - 1.6 8.8 22.0 1.3 9.1 13.2 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OWF41351.1 - 1.7 9.2 31.2 0.37 11.3 9.2 3.9 3 2 1 4 4 4 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 OWF41351.1 - 2.4 8.4 27.9 0.9 9.8 0.8 3.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF4239 PF14023.6 OWF41351.1 - 2.8 7.6 7.2 9.6 5.9 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) ATG16 PF08614.11 OWF41351.1 - 3.3 7.9 29.2 0.36 11.0 6.5 3.7 3 2 1 4 4 3 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 OWF41351.1 - 5.3 7.1 19.7 2.3 8.3 2.2 3.9 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4047 PF13256.6 OWF41351.1 - 5.7 7.1 7.6 3.1 8.0 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) LRR_6 PF13516.6 OWF41352.1 - 2.3e-16 58.4 25.5 0.0034 17.3 0.2 10.8 10 1 1 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.7 OWF41352.1 - 1.9e-10 40.8 8.0 0.0087 16.5 0.2 5.6 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OWF41352.1 - 6.7e-10 38.7 1.3 1.6e-09 37.5 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF41352.1 - 6.5e-06 25.9 0.6 2.3e-05 24.1 0.6 2.0 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 OWF41352.1 - 3.8e-05 23.4 4.9 0.0073 16.0 0.2 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 OWF41352.1 - 0.0032 17.8 9.3 7.7 7.5 0.0 7.4 7 2 0 7 7 7 1 Leucine Rich Repeat Pkinase_Tyr PF07714.17 OWF41353.1 - 7.3e-85 284.4 0.0 1.1e-84 283.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF41353.1 - 4.3e-36 124.6 0.0 7.9e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain MAM PF00629.23 OWF41353.1 - 0.0002 21.3 0.3 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Pkinase_fungal PF17667.1 OWF41353.1 - 0.028 13.2 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pro-kuma_activ PF09286.11 OWF41353.1 - 0.042 14.1 0.2 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain DHHC PF01529.20 OWF41353.1 - 3.8 7.6 5.8 0.29 11.3 0.3 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase PITH PF06201.13 OWF41354.1 - 4e-41 140.7 0.1 2.6e-40 138.1 0.0 1.9 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 OWF41354.1 - 5e-25 87.5 0.5 8.9e-25 86.7 0.5 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OWF41354.1 - 0.00033 20.9 0.0 0.0006 20.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OWF41354.1 - 0.0033 17.3 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OWF41354.1 - 0.0093 16.4 0.3 0.35 11.3 0.3 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 OWF41354.1 - 0.019 14.7 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 Redoxin zf-C2H2 PF00096.26 OWF41355.1 - 1.3e-23 82.1 67.3 3e-06 27.4 0.4 8.8 8 1 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF41355.1 - 4.4e-23 80.6 58.0 2.2e-08 34.1 0.9 9.3 10 0 0 10 10 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF41355.1 - 1.2e-17 63.1 61.2 0.0016 19.1 0.4 8.6 8 0 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.7 OWF41355.1 - 5.5e-10 39.3 45.3 0.061 13.7 0.5 8.4 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF41355.1 - 1.1e-06 28.7 37.5 0.014 15.7 0.1 8.3 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 OWF41355.1 - 3.8e-05 23.5 10.4 0.0041 17.0 1.2 5.1 3 1 2 5 5 5 2 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 OWF41355.1 - 7.6e-05 22.6 5.4 0.0013 18.7 0.5 7.1 8 1 0 8 8 7 3 C2H2-type zinc finger DUF3268 PF11672.8 OWF41355.1 - 0.0063 16.8 10.4 2.2 8.7 0.3 3.9 4 0 0 4 4 4 2 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 OWF41355.1 - 0.015 15.4 1.0 0.015 15.4 1.0 6.1 4 2 3 7 7 7 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 OWF41355.1 - 0.026 14.9 34.3 0.18 12.1 0.8 6.4 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 OWF41355.1 - 0.057 13.3 0.4 0.057 13.3 0.4 5.0 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 OWF41355.1 - 0.068 13.1 0.1 0.068 13.1 0.1 6.7 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-CCHC_2 PF13696.6 OWF41355.1 - 0.11 12.4 0.3 0.11 12.4 0.3 5.0 5 0 0 5 5 5 0 Zinc knuckle zf-Dof PF02701.15 OWF41355.1 - 0.11 12.6 9.6 3.3 7.9 0.5 4.4 2 1 2 4 4 3 0 Dof domain, zinc finger Vps36-NZF-N PF16988.5 OWF41355.1 - 0.18 11.2 10.4 2.7 7.5 0.2 4.3 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Lectin_C PF00059.21 OWF41356.1 - 7.1e-16 58.9 3.2 7.1e-16 58.9 3.2 1.7 2 0 0 2 2 2 1 Lectin C-type domain DUF390 PF04094.14 OWF41356.1 - 0.0024 16.2 2.2 0.0032 15.9 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF390) PEMT PF04191.13 OWF41357.1 - 1.7e-28 99.1 5.0 1.7e-28 99.1 5.0 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase MYCBPAP PF14646.6 OWF41358.1 - 8.2e-62 209.6 0.0 1.3e-61 208.9 0.0 1.3 1 0 0 1 1 1 1 MYCBP-associated protein family Tox-MPTase3 PF15639.6 OWF41358.1 - 0.035 14.0 0.4 0.19 11.6 0.4 2.1 1 1 0 1 1 1 0 Metallopeptidase toxin 3 WD40 PF00400.32 OWF41359.1 - 1.5e-25 89.0 12.3 1.3e-06 29.0 0.1 9.6 10 0 0 10 10 10 5 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OWF41359.1 - 0.00054 18.8 6.1 0.47 9.1 0.0 4.5 4 1 1 5 5 5 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 OWF41359.1 - 0.0042 17.4 1.0 0.085 13.2 0.1 3.8 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF41359.1 - 0.047 12.6 0.7 0.38 9.7 0.1 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_8 PF13833.6 OWF41359.1 - 0.095 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 OWF41359.1 - 0.11 13.0 0.2 0.33 11.4 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair MFS_1 PF07690.16 OWF41360.1 - 1.2e-14 54.0 50.0 1.2e-09 37.6 18.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF5527 PF17665.1 OWF41360.1 - 0.009 15.6 0.3 0.12 11.9 0.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5527) SH2 PF00017.24 OWF41361.1 - 1.4e-13 50.7 0.0 3.8e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain TbpB_C PF17483.2 OWF41361.1 - 0.12 12.7 0.0 0.46 10.9 0.0 1.9 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B SH2_2 PF14633.6 OWF41361.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 SH2 domain TIR_2 PF13676.6 OWF41362.1 - 2.1e-16 60.6 0.1 1.1e-15 58.2 0.0 2.2 2 1 1 3 3 3 1 TIR domain TIR PF01582.20 OWF41362.1 - 6.3e-14 52.2 0.2 9.8e-14 51.5 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF41362.1 - 2.3e-11 43.3 0.5 2.3e-05 24.0 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF41362.1 - 3.4e-06 27.3 3.7 0.0094 16.4 0.1 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF41362.1 - 0.0049 17.2 0.6 58 4.8 0.2 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF41362.1 - 0.027 14.5 5.4 7.1 7.0 0.1 3.9 3 1 1 4 4 4 0 Leucine Rich repeat Lectin_C PF00059.21 OWF41363.1 - 8.5e-08 32.9 6.2 8.3e-06 26.5 0.8 3.1 2 2 1 3 3 3 2 Lectin C-type domain HemolysinCabind PF00353.19 OWF41364.1 - 0.00011 22.2 36.8 0.0053 16.7 8.1 3.7 3 1 0 3 3 3 3 RTX calcium-binding nonapeptide repeat (4 copies) fn3 PF00041.21 OWF41365.1 - 2e-26 92.2 12.8 4.2e-08 33.4 0.3 4.2 4 0 0 4 4 4 4 Fibronectin type III domain Interfer-bind PF09294.10 OWF41365.1 - 6.4e-05 23.2 0.2 1.4 9.3 0.0 3.9 3 1 1 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 OWF41365.1 - 0.0025 18.4 18.6 0.72 10.5 0.5 4.8 2 1 2 4 4 4 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 OWF41365.1 - 0.01 16.2 7.9 8.1 6.9 0.1 4.2 4 0 0 4 4 4 2 Uncharacterised conserved protein (DUF2369) He_PIG_assoc PF10632.9 OWF41365.1 - 0.17 11.6 2.2 14 5.4 0.2 2.9 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase HTH_26 PF13443.6 OWF41366.1 - 3.5e-18 65.8 57.4 1.6e+02 2.8 0.0 28.3 3 2 27 31 31 31 27 Cro/C1-type HTH DNA-binding domain fn3 PF00041.21 OWF41368.1 - 1.6e-83 275.1 73.7 9e-12 45.2 3.2 13.4 12 2 0 12 12 12 10 Fibronectin type III domain Y_phosphatase PF00102.27 OWF41368.1 - 2.7e-81 272.6 0.0 5.3e-81 271.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 OWF41368.1 - 3.5e-11 43.5 74.9 0.011 16.2 1.3 10.3 7 1 2 10 10 10 7 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF41368.1 - 4.2e-05 23.8 19.8 0.72 10.2 0.1 8.3 8 0 0 8 8 8 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 OWF41368.1 - 8.5e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2369 PF10179.9 OWF41368.1 - 0.0052 17.1 28.9 5.9 7.3 0.2 9.2 8 2 2 10 10 10 2 Uncharacterised conserved protein (DUF2369) Y_phosphatase3 PF13350.6 OWF41368.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OWF41368.1 - 0.022 14.9 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate PTP_tm PF18861.1 OWF41368.1 - 0.26 11.3 8.1 48 3.9 0.0 5.2 3 1 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF1517 PF07466.11 OWF41368.1 - 0.48 10.5 1.5 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) DUF4006 PF13179.6 OWF41368.1 - 0.73 9.8 4.0 0.45 10.5 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF4006) fn3_2 PF16893.5 OWF41368.1 - 0.95 9.7 14.3 3.9 7.7 0.0 6.4 8 0 0 8 8 7 0 Fibronectin type III domain VWC PF00093.18 OWF41369.1 - 7e-155 503.5 788.1 1.7e-10 41.0 16.2 39.6 38 2 2 40 40 40 33 von Willebrand factor type C domain Tyrosinase PF00264.20 OWF41369.1 - 9.7e-42 143.7 12.1 1.4e-19 71.2 2.8 4.4 3 1 0 3 3 3 3 Common central domain of tyrosinase VWD PF00094.25 OWF41369.1 - 1.4e-31 109.9 0.2 3.4e-31 108.7 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain S4 PF01479.25 OWF41369.1 - 0.25 11.1 0.7 4.2 7.2 0.1 2.9 3 0 0 3 3 3 0 S4 domain DENN PF02141.21 OWF41370.1 - 1.2e-56 191.6 3.3 2.6e-56 190.6 3.3 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.19 OWF41370.1 - 6.7e-32 110.3 0.1 3.1e-21 75.8 0.3 2.9 2 0 0 2 2 2 2 RUN domain dDENN PF03455.19 OWF41370.1 - 3e-16 59.1 1.3 1.2e-15 57.2 1.3 2.2 1 0 0 1 1 1 1 dDENN domain PLAT PF01477.23 OWF41370.1 - 4.8e-10 40.0 0.0 9.8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain uDENN PF03456.18 OWF41370.1 - 2.7e-09 37.6 0.1 9.5e-09 35.9 0.1 2.1 1 0 0 1 1 1 1 uDENN domain LRR_8 PF13855.6 OWF41371.1 - 2e-19 69.1 41.4 7.1e-07 28.9 1.7 6.2 3 3 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 OWF41371.1 - 1.5e-13 50.7 45.0 2.4e-05 24.6 0.3 7.8 5 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF41371.1 - 0.014 15.8 40.3 9.6 7.2 0.1 10.6 11 1 1 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF41371.1 - 0.24 11.6 28.4 6.9 7.0 0.2 9.2 10 0 0 10 10 10 0 Leucine Rich repeat LRR_9 PF14580.6 OWF41371.1 - 0.72 9.3 13.4 0.072 12.6 2.2 3.4 1 1 4 5 5 5 0 Leucine-rich repeat Coatomer_E PF04733.14 OWF41372.1 - 4.9e-113 377.3 5.8 5.6e-113 377.1 5.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 OWF41372.1 - 6.1e-09 36.0 7.2 0.0002 21.5 0.6 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OWF41372.1 - 1e-07 32.4 7.9 0.0016 18.9 1.1 3.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF41372.1 - 2e-06 28.1 1.6 3.8 8.6 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF41372.1 - 3.5e-05 23.6 5.1 0.32 11.2 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF41372.1 - 0.0002 21.6 1.6 0.13 12.6 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF41372.1 - 0.0027 18.3 3.2 0.6 10.8 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF41372.1 - 0.0088 16.0 2.9 1.6 8.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF41372.1 - 0.014 15.2 6.8 0.27 11.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OWF41372.1 - 0.036 14.1 6.6 0.43 10.6 3.9 2.9 1 1 1 2 2 2 0 Putative TPR-like repeat TPR_6 PF13174.6 OWF41372.1 - 0.056 14.1 4.0 9.1 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ig_3 PF13927.6 OWF41373.1 - 7.5e-21 74.5 3.2 7.3e-12 45.7 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF41373.1 - 4.8e-17 61.8 0.5 2.9e-13 49.7 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF41373.1 - 6.5e-14 52.0 4.4 4.4e-08 33.3 0.1 4.1 2 1 1 3 3 3 3 Immunoglobulin domain ig PF00047.25 OWF41373.1 - 5.4e-12 45.7 4.1 1.7e-06 28.1 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF41373.1 - 1.7e-11 44.3 6.1 0.00072 19.7 0.1 5.3 3 3 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF41373.1 - 0.00091 18.7 0.0 4 7.1 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 OWF41373.1 - 0.0018 18.3 0.1 1.4 9.0 0.0 3.5 3 1 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 OWF41373.1 - 0.047 13.8 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain AAA_2 PF07724.14 OWF41374.1 - 2.2e-38 132.1 0.0 4.2e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OWF41374.1 - 1.8e-16 60.8 0.0 3.9e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OWF41374.1 - 1e-07 31.9 0.0 2.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 OWF41374.1 - 6.1e-06 26.0 0.0 4.1e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 OWF41374.1 - 7.5e-06 26.3 0.4 4e-05 23.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OWF41374.1 - 5e-05 22.8 0.0 0.012 15.0 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 OWF41374.1 - 0.00019 20.6 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.14 OWF41374.1 - 0.00019 21.4 0.0 0.00093 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OWF41374.1 - 0.00046 20.0 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 OWF41374.1 - 0.00098 19.5 0.3 0.018 15.5 0.1 2.6 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OWF41374.1 - 0.0014 18.4 0.0 0.0049 16.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 OWF41374.1 - 0.0053 15.9 0.1 0.016 14.3 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activ_2 PF14532.6 OWF41374.1 - 0.01 16.0 0.0 0.059 13.5 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 OWF41374.1 - 0.016 15.7 0.5 0.1 13.1 0.1 2.3 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 OWF41374.1 - 0.022 14.1 0.5 3.2 7.0 0.1 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 OWF41374.1 - 0.024 14.2 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OWF41374.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OWF41374.1 - 0.033 13.9 0.4 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OWF41374.1 - 0.047 13.5 0.3 0.39 10.5 0.0 2.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase Benyvirus_14KDa PF07255.11 OWF41374.1 - 0.053 13.7 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Benyvirus 14KDa protein AAA_29 PF13555.6 OWF41374.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 OWF41374.1 - 0.098 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 OWF41374.1 - 0.12 12.6 0.2 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OWF41374.1 - 1.3 9.4 7.1 1.6 9.2 0.4 2.4 1 1 1 2 2 2 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 OWF41375.1 - 1.9e-35 123.2 16.8 2.5e-35 122.8 16.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 OWF41375.1 - 0.043 13.6 15.1 0.055 13.3 15.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 OWF41375.1 - 0.49 10.3 12.2 0.71 9.8 12.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 OWF41375.1 - 0.91 8.8 20.3 1.3 8.3 20.3 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 OWF41375.1 - 2.5 6.8 9.5 3.3 6.4 9.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LysM PF01476.20 OWF41376.1 - 0.00033 20.7 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 LysM domain 5-FTHF_cyc-lig PF01812.20 OWF41377.1 - 2.5e-47 161.1 0.0 2.9e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family UPF0258 PF06789.12 OWF41378.1 - 0.0063 16.7 0.2 0.014 15.5 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) DUF608 PF04685.13 OWF41379.1 - 6.7e-158 525.6 7.2 9.5e-158 525.1 7.2 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 OWF41379.1 - 1.7e-83 280.7 0.0 3.3e-83 279.7 0.0 1.4 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Bac_rhamnosid6H PF17389.2 OWF41379.1 - 9.5e-06 25.1 0.7 1.5e-05 24.5 0.7 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 OWF41379.1 - 0.035 13.0 0.1 0.071 12.0 0.1 1.4 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DUF829 PF05705.14 OWF41380.1 - 8.8e-31 107.6 0.1 1.4e-30 106.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ints3 PF10189.9 OWF41380.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Integrator complex subunit 3 Homeodomain PF00046.29 OWF41381.1 - 2.5e-24 84.9 4.6 4.9e-24 83.9 4.6 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 OWF41381.1 - 2.9e-09 36.4 0.3 9.5e-09 34.8 0.3 2.0 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF41381.1 - 0.077 12.9 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 OWF41382.1 - 1.7e-24 85.4 8.0 2e-24 85.2 6.3 1.9 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 OWF41382.1 - 1.5e-07 31.0 2.6 3.1e-07 30.0 2.6 1.6 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF41382.1 - 0.022 14.6 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Neur_chan_LBD PF02931.23 OWF41383.1 - 1.2e-56 191.5 0.2 1.6e-56 191.1 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41383.1 - 5.9e-29 101.8 5.6 3.5e-26 92.7 1.3 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2013 PF09431.10 OWF41383.1 - 0.16 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) DUF983 PF06170.12 OWF41383.1 - 4.5 7.8 11.2 16 5.9 3.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Flavodoxin_2 PF02525.17 OWF41384.1 - 0.18 11.5 0.3 1.8 8.2 0.1 2.3 1 1 0 2 2 2 0 Flavodoxin-like fold BRI3BP PF14965.6 OWF41384.1 - 4.9 6.6 8.8 27 4.2 0.3 3.2 1 1 3 4 4 4 0 Negative regulator of p53/TP53 Neur_chan_memb PF02932.16 OWF41385.1 - 3.6e-31 109.1 3.7 3.2e-27 96.1 0.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF41385.1 - 3.2e-30 105.2 0.1 4.5e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF983 PF06170.12 OWF41385.1 - 2.1 8.8 11.9 9.8 6.7 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Ig_3 PF13927.6 OWF41386.1 - 4.2e-07 30.5 2.6 0.1 13.2 0.1 3.7 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 OWF41386.1 - 0.00069 19.8 1.3 0.036 14.2 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF41386.1 - 0.0045 17.0 0.3 0.043 13.9 0.3 2.7 1 1 1 2 2 2 1 CD80-like C2-set immunoglobulin domain CBM_35 PF16990.5 OWF41386.1 - 0.099 12.9 0.9 0.41 10.9 0.0 2.5 3 0 0 3 3 3 0 Carbohydrate binding module (family 35) DUF4402 PF14352.6 OWF41386.1 - 0.16 12.7 2.1 0.28 11.8 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) I-set PF07679.16 OWF41387.1 - 0.00043 20.3 0.2 0.67 10.1 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF41387.1 - 0.0012 19.4 0.3 0.018 15.6 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 OWF41387.1 - 0.003 17.7 0.1 0.034 14.3 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF41387.1 - 0.0045 17.3 2.5 0.021 15.2 0.2 3.1 3 1 0 3 3 3 1 Immunoglobulin domain Invasin_D3 PF09134.10 OWF41387.1 - 0.068 13.5 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 Invasin, domain 3 PulA_N1 PF17999.1 OWF41387.1 - 0.16 12.7 0.2 0.91 10.3 0.0 2.4 3 0 0 3 3 3 0 Pullulanase N1-terminal domain Alba PF01918.21 OWF41388.1 - 2.7e-12 46.3 10.8 2.7 7.9 0.2 9.1 1 1 2 3 3 3 1 Alba 7tm_6 PF02949.20 OWF41388.1 - 1.8e-08 33.9 27.3 0.83 8.7 0.8 6.8 1 1 2 3 3 3 2 7tm Odorant receptor HAD_SAK_2 PF18143.1 OWF41388.1 - 4.1e-08 33.6 7.0 13 6.1 7.0 6.2 1 1 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins Retrotrans_gag PF03732.17 OWF41388.1 - 8e-07 29.3 15.5 1.1e+04 -3.3 15.5 6.8 1 1 0 1 1 1 0 Retrotransposon gag protein Rpp20 PF12328.8 OWF41388.1 - 2.1e-05 24.5 8.9 4.5 7.2 0.7 5.4 1 1 2 3 3 3 3 Rpp20 subunit of nuclear RNase MRP and P HTH_DeoR PF08220.12 OWF41388.1 - 0.00057 19.6 20.6 39 4.1 0.1 8.4 1 1 12 15 15 15 0 DeoR-like helix-turn-helix domain Vac_Fusion PF02346.16 OWF41388.1 - 0.0038 16.8 11.8 16 5.2 0.5 5.4 1 1 6 7 7 7 0 Chordopoxvirus multifunctional envelope protein A27 Tma16 PF11176.8 OWF41388.1 - 0.0042 17.0 11.4 5.1 7.0 1.1 4.0 1 1 3 4 4 4 4 Translation machinery-associated protein 16 DUF1211 PF06736.11 OWF41388.1 - 0.0045 17.4 11.5 6.7 7.2 1.9 4.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1211) Gp45_2 PF17470.2 OWF41388.1 - 0.014 15.3 18.8 80 3.3 0.1 7.8 1 1 14 15 15 15 0 Phage gene product 45.2 DUF3332 PF11810.8 OWF41388.1 - 0.32 10.6 9.3 2.9 7.5 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3332) BNR_4 PF15892.5 OWF41388.1 - 3.8 6.8 38.0 1.8e+04 -20.1 38.0 4.5 1 1 0 1 1 0 0 BNR repeat-containing family member NHL PF01436.21 OWF41390.1 - 0.095 12.8 0.0 12 6.2 0.0 3.8 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.11 OWF41390.1 - 0.52 10.7 4.0 1.4 9.4 0.0 3.5 4 0 0 4 4 4 0 Two component regulator propeller p450 PF00067.22 OWF41391.1 - 1.9e-109 366.5 0.0 2.5e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Calponin PF00402.18 OWF41392.1 - 4.2e-81 266.1 73.4 3e-14 52.3 0.7 8.6 9 0 0 9 9 9 7 Calponin family repeat CH PF00307.31 OWF41392.1 - 1.2e-15 57.6 0.0 1.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Cas_VVA1548 PF09652.10 OWF41392.1 - 0.1 12.8 2.7 0.75 10.1 0.1 3.4 2 2 3 5 5 5 0 Putative CRISPR-associated protein (Cas_VVA1548) WD40 PF00400.32 OWF41393.1 - 2.5e-15 56.6 6.1 0.0073 17.1 0.0 8.0 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF41393.1 - 2.5e-06 27.7 0.0 0.71 10.2 0.0 4.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 OWF41393.1 - 0.019 14.8 1.6 0.035 14.0 0.0 2.3 2 1 2 4 4 4 0 HELP motif DUF3800 PF12686.7 OWF41393.1 - 0.67 10.6 4.7 2e+02 2.6 3.1 4.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Tox-ART-HYD1 PF15633.6 OWF41395.1 - 4.1e-07 30.6 0.1 6.3e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase PARP PF00644.20 OWF41395.1 - 0.018 14.7 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain HpcH_HpaI PF03328.14 OWF41395.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Tox-ART-HYD1 PF15633.6 OWF41396.1 - 3.8e-08 33.9 0.1 5.4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase Tox-ART-HYD1 PF15633.6 OWF41397.1 - 7e-05 23.4 0.0 8.8e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase PARP PF00644.20 OWF41397.1 - 0.0056 16.3 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Med8 PF10232.9 OWF41398.1 - 1.6e-77 260.2 9.7 1.9e-77 260.0 9.7 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4047 PF13256.6 OWF41398.1 - 0.18 12.0 2.2 2.4 8.3 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) DnaJ_C PF01556.18 OWF41399.1 - 1.8e-42 144.9 0.4 2.6e-42 144.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OWF41399.1 - 5.7e-28 96.8 3.4 6.9e-28 96.6 2.5 1.6 2 0 0 2 2 2 1 DnaJ domain DUF389 PF04087.14 OWF41400.1 - 1.3e-42 145.2 7.7 2e-42 144.6 7.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF389) Death PF00531.22 OWF41400.1 - 0.03 14.5 0.4 0.062 13.5 0.4 1.5 1 0 0 1 1 1 0 Death domain Gemini_C4 PF01492.17 OWF41400.1 - 0.033 14.1 1.7 0.12 12.2 1.7 2.1 1 0 0 1 1 1 0 Geminivirus C4 protein LRR_8 PF13855.6 OWF41401.1 - 7.9e-36 121.6 33.9 4.7e-09 35.9 0.1 6.6 4 2 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OWF41401.1 - 4.8e-34 115.8 30.2 6.3e-06 26.4 0.4 9.0 7 1 3 10 10 10 10 Leucine Rich repeats (2 copies) PDZ PF00595.24 OWF41401.1 - 5.6e-18 65.1 0.2 2.1e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 OWF41401.1 - 3.3e-05 24.1 0.0 9.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF41401.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain LRR_1 PF00560.33 OWF41401.1 - 0.0022 18.3 27.4 42 5.2 0.4 11.6 11 2 0 11 11 11 0 Leucine Rich Repeat LRR_5 PF13306.6 OWF41401.1 - 0.0082 16.1 0.0 0.7 9.9 0.0 2.9 2 1 1 3 3 3 1 BspA type Leucine rich repeat region (6 copies) DUF240 PF03086.14 OWF41401.1 - 0.13 12.2 0.1 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF240) LRR_6 PF13516.6 OWF41401.1 - 9.1 6.6 31.6 48 4.4 0.0 9.5 10 0 0 10 10 10 0 Leucine Rich repeat CR6_interact PF10147.9 OWF41402.1 - 2.2e-21 76.5 24.6 3.5e-21 75.9 24.6 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Mitoc_mL59 PF18126.1 OWF41402.1 - 0.0046 17.2 1.0 0.0046 17.2 1.0 2.4 2 0 0 2 2 2 1 Mitochondrial ribosomal protein mL59 FUSC PF04632.12 OWF41402.1 - 0.047 12.2 1.3 0.07 11.7 1.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family XRN_M PF17846.1 OWF41402.1 - 1.1 8.1 12.7 1.7 7.5 12.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Neuralized PF07177.12 OWF41403.1 - 6.8e-40 136.5 0.0 1.4e-39 135.5 0.0 1.6 1 0 0 1 1 1 1 Neuralized TIR_2 PF13676.6 OWF41403.1 - 2.6e-23 82.9 0.0 1.3e-22 80.6 0.0 2.2 2 0 0 2 2 2 1 TIR domain COR PF16095.5 OWF41403.1 - 2.1e-19 70.1 0.0 6.2e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF41403.1 - 1.7e-16 60.5 1.6 5.8e-10 39.4 0.5 3.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF41403.1 - 6.2e-07 29.5 0.1 4.2e-06 26.8 0.1 2.4 2 0 0 2 2 2 1 Death domain Ras PF00071.22 OWF41403.1 - 2.8e-06 27.0 0.1 0.01 15.5 0.0 3.0 3 0 0 3 3 3 2 Ras family Gtr1_RagA PF04670.12 OWF41403.1 - 0.0044 16.4 0.1 0.58 9.5 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TIR PF01582.20 OWF41403.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 TIR domain Spectrin PF00435.21 OWF41404.1 - 0.023 15.2 6.3 0.023 15.2 6.3 3.5 1 1 2 3 3 3 0 Spectrin repeat HIP1_clath_bdg PF16515.5 OWF41404.1 - 0.031 14.9 36.0 0.29 11.8 9.4 4.2 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 OWF41404.1 - 0.12 12.5 43.9 0.049 13.7 12.8 3.8 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase Vip3A_N PF12495.8 OWF41404.1 - 0.12 12.3 10.0 0.057 13.3 4.2 2.4 2 1 1 3 3 3 0 Vegetative insecticide protein 3A N terminal MAD PF05557.13 OWF41404.1 - 0.19 10.1 44.6 0.013 13.9 30.8 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF5082 PF16888.5 OWF41404.1 - 0.25 11.6 31.1 1.8 8.9 12.9 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 OWF41404.1 - 0.7 8.7 43.3 0.029 13.3 15.0 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 OWF41404.1 - 2.2 8.7 40.2 0.63 10.5 24.3 3.3 1 1 3 4 4 4 0 Fez1 DUF16 PF01519.16 OWF41404.1 - 2.6 8.6 33.5 0.39 11.2 7.9 3.7 1 1 1 3 3 3 0 Protein of unknown function DUF16 SlyX PF04102.12 OWF41404.1 - 3.8 8.2 28.6 0.86 10.3 1.4 4.9 1 1 4 6 6 6 0 SlyX ATG16 PF08614.11 OWF41404.1 - 4.3 7.5 37.6 1.5 9.0 14.1 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 OWF41404.1 - 4.9 7.4 44.3 1.8 8.8 22.1 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 OWF41404.1 - 7.9 6.5 27.2 4.9 7.2 8.2 2.7 1 1 1 2 2 2 0 Laminin Domain II DUF812 PF05667.11 OWF41404.1 - 9.4 5.0 36.3 16 4.2 36.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SlyX PF04102.12 OWF41405.1 - 0.00017 22.1 18.6 0.068 13.8 0.2 4.7 2 1 2 4 4 4 2 SlyX DUF812 PF05667.11 OWF41405.1 - 0.00096 18.2 27.6 0.0012 17.8 27.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF5082 PF16888.5 OWF41405.1 - 0.0037 17.5 26.4 0.073 13.4 8.8 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF5082) TMPIT PF07851.13 OWF41405.1 - 0.0043 16.4 7.1 0.0043 16.4 7.1 3.0 1 1 2 3 3 3 1 TMPIT-like protein LPP PF04728.13 OWF41405.1 - 0.011 16.2 2.3 6.2 7.3 0.7 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Fez1 PF06818.15 OWF41405.1 - 0.013 16.0 29.6 0.41 11.1 18.9 2.8 1 1 2 3 3 3 0 Fez1 DUF4706 PF15797.5 OWF41405.1 - 0.013 16.0 0.6 0.013 16.0 0.6 2.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4706) BRE1 PF08647.11 OWF41405.1 - 0.017 15.2 4.3 0.017 15.2 4.3 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Fusion_gly PF00523.18 OWF41405.1 - 0.053 11.8 1.9 0.87 7.8 0.4 2.3 1 1 1 2 2 2 0 Fusion glycoprotein F0 ATG16 PF08614.11 OWF41405.1 - 0.062 13.5 33.3 0.034 14.4 9.3 3.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OWF41405.1 - 0.091 12.8 23.7 0.58 10.2 1.6 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 OWF41405.1 - 0.14 12.3 9.0 0.24 11.5 5.8 2.5 1 1 2 3 3 3 0 Cobalamin adenosyltransferase KASH_CCD PF14662.6 OWF41405.1 - 0.23 11.3 36.5 0.079 12.8 23.0 2.7 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 OWF41405.1 - 0.26 11.5 28.0 0.24 11.6 8.8 3.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CC2-LZ PF16516.5 OWF41405.1 - 0.26 11.7 26.3 1.9 8.9 1.4 3.6 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Lebercilin PF15619.6 OWF41405.1 - 0.36 10.4 35.4 0.031 14.0 11.8 3.5 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease GIT_CC PF16559.5 OWF41405.1 - 0.41 10.5 23.4 0.27 11.1 0.7 4.8 4 1 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 OWF41405.1 - 0.44 11.2 32.2 1.8 9.2 5.8 4.9 1 1 4 5 5 5 0 Initiation control protein YabA FlaC_arch PF05377.11 OWF41405.1 - 0.57 10.6 19.6 0.28 11.6 0.4 4.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 OWF41405.1 - 0.71 8.5 23.9 0.29 9.7 9.0 2.2 1 1 1 2 2 2 0 AAA domain ERM PF00769.19 OWF41405.1 - 0.93 9.3 33.1 0.55 10.0 17.7 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 OWF41405.1 - 0.98 9.5 34.5 1.1 9.4 8.2 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 OWF41405.1 - 1.1 8.6 19.1 7.4 5.8 18.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) She9_MDM33 PF05546.11 OWF41405.1 - 1.4 8.7 18.6 0.12 12.2 5.5 2.7 1 1 0 2 2 2 0 She9 / Mdm33 family Spc7 PF08317.11 OWF41405.1 - 1.8 7.3 34.6 2.7 6.8 15.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DASH_Hsk3 PF08227.11 OWF41405.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.5 5 1 1 6 6 2 0 DASH complex subunit Hsk3 like PRKG1_interact PF15898.5 OWF41405.1 - 1.9 9.4 29.9 1.2 10.0 9.4 3.0 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Plk4_PB2 PF18409.1 OWF41405.1 - 2.3 9.0 10.8 1.6 9.5 1.2 2.8 1 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 HMMR_N PF15905.5 OWF41405.1 - 2.3 7.6 34.5 1.4 8.3 22.7 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SpecificRecomb PF10136.9 OWF41405.1 - 2.5 6.3 5.6 3.5 5.8 5.6 1.2 1 0 0 1 1 1 0 Site-specific recombinase WXG100 PF06013.12 OWF41405.1 - 3.1 8.1 8.8 0.85 9.9 1.6 3.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG APG6_N PF17675.1 OWF41405.1 - 3.1 8.3 33.2 1.2e+02 3.1 23.7 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 OWF41405.1 - 3.2 7.9 33.6 0.3 11.2 15.4 3.0 1 1 2 3 3 2 0 Tropomyosin like DUF4200 PF13863.6 OWF41405.1 - 3.3 8.1 33.4 4.3 7.8 8.9 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) Laminin_II PF06009.12 OWF41405.1 - 3.8 7.5 22.0 1.2 9.2 6.6 2.9 1 1 0 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 OWF41405.1 - 4.5 7.3 37.3 0.97 9.4 17.6 3.6 1 1 2 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3573 PF12097.8 OWF41405.1 - 5.1 5.8 11.5 1.5 7.6 1.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3573) HIP1_clath_bdg PF16515.5 OWF41405.1 - 6.2 7.5 33.2 0.86 10.2 6.1 3.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Spc19 PF08287.11 OWF41405.1 - 6.3 6.7 29.5 1.3 8.9 9.8 2.9 1 1 2 3 3 3 0 Spc19 DUF724 PF05266.14 OWF41405.1 - 6.4 6.5 32.9 0.57 10.0 11.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 OWF41405.1 - 8.3 6.4 23.7 0.31 11.0 2.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) XhlA PF10779.9 OWF41405.1 - 8.4 6.7 21.4 1 9.6 1.6 4.0 3 2 1 4 4 3 0 Haemolysin XhlA DUF641 PF04859.12 OWF41405.1 - 8.4 6.7 30.6 0.38 11.1 5.7 4.1 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) DUF2203 PF09969.9 OWF41405.1 - 8.6 7.1 20.9 4 8.2 3.0 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF848 PF05852.11 OWF41405.1 - 8.7 6.4 19.0 0.13 12.3 4.2 3.1 1 1 2 3 3 2 0 Gammaherpesvirus protein of unknown function (DUF848) IF-2B PF01008.17 OWF41405.1 - 9.3 5.4 9.6 5.5 6.1 2.9 2.4 1 1 1 2 2 2 0 Initiation factor 2 subunit family Seryl_tRNA_N PF02403.22 OWF41405.1 - 9.4 6.5 28.1 0.14 12.4 5.2 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Profilin PF00235.19 OWF41406.1 - 6.2e-18 65.3 0.0 7e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Profilin HSP70 PF00012.20 OWF41407.1 - 1.5e-253 842.5 8.3 1.7e-253 842.3 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF41407.1 - 6.2e-16 58.1 0.0 1.6e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OWF41407.1 - 0.00035 20.9 3.7 1 9.9 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA StbA PF06406.11 OWF41407.1 - 0.0093 15.2 0.0 0.026 13.8 0.0 1.7 1 0 0 1 1 1 1 StbA protein BcrAD_BadFG PF01869.20 OWF41407.1 - 0.021 14.3 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 OWF41407.1 - 0.028 13.7 0.6 0.077 12.2 0.0 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 OWF41407.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF883 PF05957.13 OWF41407.1 - 2.3 8.9 5.5 4.2 8.1 1.3 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) AAA_23 PF13476.6 OWF41408.1 - 7.9e-19 68.9 4.1 7.9e-19 68.9 4.1 6.0 3 2 1 4 4 4 1 AAA domain SMC_N PF02463.19 OWF41408.1 - 4.5e-16 59.0 34.5 5.8e-15 55.3 34.5 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OWF41408.1 - 4.4e-10 39.8 12.8 4.4e-10 39.8 12.8 3.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 OWF41408.1 - 0.00025 20.9 17.2 0.0046 16.8 1.1 4.3 2 2 3 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OWF41408.1 - 0.0028 17.3 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OWF41408.1 - 1.6 8.0 6.4 2.4 7.4 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 OWF41408.1 - 7.6 6.4 9.1 0.24 11.3 0.1 3.2 3 0 0 3 3 3 0 RsgA GTPase HNF-1_N PF04814.13 OWF41409.1 - 3.2e-11 44.2 2.4 3.5e-11 44.1 0.9 1.9 2 1 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 OWF41409.1 - 3.4e-11 42.8 3.5 9.5e-11 41.4 1.7 2.7 2 1 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF41409.1 - 0.0002 21.2 0.0 0.00063 19.6 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain MerR_1 PF13411.6 OWF41409.1 - 0.041 14.0 0.0 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein FANCI_S4 PF14678.6 OWF41409.1 - 0.11 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 V-set PF07686.17 OWF41413.1 - 1.1e-12 48.1 10.6 0.062 13.5 0.3 5.6 5 0 0 5 5 5 4 Immunoglobulin V-set domain I-set PF07679.16 OWF41413.1 - 9.9e-07 28.8 14.0 0.011 15.8 0.0 7.4 8 1 0 8 8 8 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF41413.1 - 3.5e-06 27.5 21.6 0.57 10.8 0.1 9.3 9 0 0 9 9 9 2 Immunoglobulin domain ig PF00047.25 OWF41413.1 - 0.022 14.9 26.9 2.6 8.3 0.1 8.8 10 1 0 10 10 10 0 Immunoglobulin domain APG12 PF04110.13 OWF41413.1 - 0.073 13.5 0.5 26 5.3 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 CBM_14 PF01607.24 OWF41413.1 - 0.19 11.9 31.1 0.034 14.3 3.4 5.1 5 0 0 5 5 5 0 Chitin binding Peritrophin-A domain C2-set PF05790.15 OWF41413.1 - 2.1 8.6 9.2 21 5.4 0.1 5.7 6 0 0 6 6 6 0 Immunoglobulin C2-set domain Xan_ur_permease PF00860.20 OWF41414.1 - 1e-54 185.7 10.3 1e-54 185.7 10.3 1.5 2 0 0 2 2 2 1 Permease family FAM70 PF14967.6 OWF41414.1 - 1.8 7.9 5.6 3 7.2 5.6 1.3 1 0 0 1 1 1 0 FAM70 protein I-set PF07679.16 OWF41415.1 - 3.1e-06 27.1 9.1 0.0084 16.2 0.0 6.0 5 1 0 5 5 5 3 Immunoglobulin I-set domain CBM_14 PF01607.24 OWF41415.1 - 0.32 11.2 25.6 0.071 13.3 3.4 3.7 4 0 0 4 4 4 0 Chitin binding Peritrophin-A domain Xan_ur_permease PF00860.20 OWF41416.1 - 1.8e-83 280.5 33.9 1.8e-83 280.5 33.9 1.3 2 0 0 2 2 2 1 Permease family DUF3671 PF12420.8 OWF41416.1 - 5.1 7.2 7.1 2.3 8.3 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function zf-C3HC4_2 PF13923.6 OWF41417.1 - 1.3e-08 34.5 12.8 3.5e-08 33.1 12.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF41417.1 - 7.5e-08 32.1 12.3 1.9e-07 30.8 12.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF41417.1 - 3.5e-07 30.0 12.2 8.8e-07 28.7 12.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF41417.1 - 2.2e-06 27.7 13.6 6.4e-06 26.2 13.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF41417.1 - 2.8e-06 27.2 9.5 7.6e-06 25.9 9.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OWF41417.1 - 3.2e-06 26.9 10.0 7.9e-06 25.6 9.4 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF41417.1 - 3.1e-05 23.8 8.2 8.1e-05 22.5 8.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF41417.1 - 0.0001 22.6 14.5 0.00034 20.9 14.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 OWF41417.1 - 0.051 13.4 8.7 0.094 12.5 7.5 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 OWF41417.1 - 0.73 10.0 5.7 0.2 11.8 1.4 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 OWF41417.1 - 3.5 7.8 9.2 8.8 6.5 9.2 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 CBM_14 PF01607.24 OWF41418.1 - 1.4e-22 79.6 29.4 1.8e-10 40.8 4.0 3.8 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain SEA PF01390.20 OWF41418.1 - 5e-08 33.0 0.1 4.7e-07 29.9 0.0 2.6 1 1 1 2 2 2 1 SEA domain V-set PF07686.17 OWF41418.1 - 5.8e-08 32.9 3.4 0.00012 22.2 0.1 3.9 5 0 0 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF41418.1 - 1.3e-06 28.4 6.8 0.00025 21.0 0.1 4.1 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 OWF41418.1 - 1.8e-06 28.5 13.0 0.08 13.5 0.1 5.7 5 1 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 OWF41418.1 - 3.9e-05 23.6 4.2 0.042 13.9 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_6 PF18452.1 OWF41418.1 - 0.0001 21.8 0.0 0.41 10.3 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 OWF41418.1 - 0.051 13.6 0.2 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Abhydrolase_3 PF07859.13 OWF41419.1 - 1.1e-57 195.3 0.2 2.1e-43 148.7 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OWF41419.1 - 6.1e-11 41.9 0.1 1.9e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OWF41419.1 - 5.9e-07 28.7 0.1 8.2e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OWF41419.1 - 0.00019 21.0 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 OWF41419.1 - 0.00068 18.4 0.1 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 OWF41419.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.11 OWF41419.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase SSF PF00474.17 OWF41421.1 - 9.6e-36 123.5 25.3 1.3e-35 123.1 25.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Lig_chan PF00060.26 OWF41423.1 - 1.4e-27 96.3 0.3 5.3e-27 94.5 0.1 2.0 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF41423.1 - 2.7e-26 92.0 0.0 5.4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF41423.1 - 1.1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TSP_1 PF00090.19 OWF41424.1 - 9e-08 32.2 27.6 2.4e-05 24.5 12.6 2.8 2 1 0 2 2 2 2 Thrombospondin type 1 domain 7tm_1 PF00001.21 OWF41425.1 - 9e-21 74.4 19.3 1.1e-20 74.0 19.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF41425.1 - 1.5e-05 24.7 17.5 1.5e-05 24.7 17.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx WBP-1 PF11669.8 OWF41425.1 - 1.7 9.4 6.0 2.9 8.6 0.1 3.0 2 1 0 2 2 2 0 WW domain-binding protein 1 TIR PF01582.20 OWF41427.1 - 1.6e-20 73.6 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF41427.1 - 1.9e-18 67.2 0.0 2.1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 OWF41427.1 - 0.00056 20.2 0.3 0.0012 19.2 0.3 1.7 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_8 PF13855.6 OWF41428.1 - 3.4e-14 52.4 7.0 5e-08 32.6 0.3 3.6 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF41428.1 - 1.8e-06 28.2 15.6 0.00093 19.6 3.9 4.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF41428.1 - 1.3e-05 25.1 4.8 0.038 14.5 0.2 4.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 OWF41428.1 - 0.037 14.1 13.0 6.2 7.1 0.6 4.9 5 0 0 5 5 5 0 Leucine Rich repeat TIR PF01582.20 OWF41429.1 - 4.9e-19 68.8 0.0 9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF41429.1 - 4.3e-18 64.8 31.0 1.3e-08 34.4 12.1 5.3 3 1 2 5 5 5 5 Leucine rich repeat TIR_2 PF13676.6 OWF41429.1 - 1.2e-15 58.2 0.0 2.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF41429.1 - 6.8e-08 32.7 40.6 1.8e-05 25.0 6.3 7.6 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF41429.1 - 0.0017 17.9 10.2 0.26 10.8 4.4 3.6 3 1 1 4 4 4 2 Leucine-rich repeat DUF1863 PF08937.11 OWF41429.1 - 0.004 17.5 0.2 0.021 15.1 0.2 2.2 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_6 PF13516.6 OWF41429.1 - 0.019 15.0 0.1 0.019 15.0 0.1 6.8 8 0 0 8 8 8 0 Leucine Rich repeat LRR_5 PF13306.6 OWF41429.1 - 0.04 13.9 8.9 0.023 14.7 1.7 3.6 4 1 1 5 5 5 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF41429.1 - 2 9.3 32.2 1.3 9.8 1.5 7.8 8 1 0 8 8 8 0 Leucine Rich Repeat Thyroglobulin_1 PF00086.18 OWF41430.1 - 6.1e-18 64.3 9.2 7.8e-09 35.1 0.3 2.3 2 1 0 2 2 2 2 Thyroglobulin type-1 repeat TSP_1 PF00090.19 OWF41431.1 - 4.1e-23 81.3 123.7 1e-09 38.4 4.9 9.1 8 1 0 8 8 8 6 Thrombospondin type 1 domain TIL PF01826.17 OWF41431.1 - 4.5e-06 26.8 41.4 1.8e-05 24.9 13.4 11.1 6 2 3 9 9 9 2 Trypsin Inhibitor like cysteine rich domain DUF3053 PF11254.8 OWF41432.1 - 0.011 15.4 0.6 0.013 15.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) CedA PF10729.9 OWF41435.1 - 2.2 8.2 9.7 49 3.9 0.2 3.4 1 1 3 4 4 4 0 Cell division activator CedA DUF5453 PF17534.2 OWF41435.1 - 3.2 7.7 18.9 22 4.9 5.6 3.1 1 1 1 2 2 2 0 Family of unknown function (DUF5453) T7SS_ESX_EspC PF10824.8 OWF41436.1 - 0.024 15.1 0.2 0.024 15.1 0.2 1.1 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Cluap1 PF10234.9 OWF41436.1 - 0.061 12.7 0.3 0.063 12.7 0.3 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1572 PF07609.11 OWF41436.1 - 0.12 12.2 0.2 0.13 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) Defensin_big PF14862.6 OWF41436.1 - 5 7.5 5.7 37 4.7 5.7 2.0 1 1 0 1 1 1 0 Big defensin Sulfotransfer_1 PF00685.27 OWF41437.1 - 1.7e-46 158.9 1.4 5.9e-45 153.8 1.4 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF41437.1 - 0.00012 22.6 0.0 0.0017 18.8 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family Cu-oxidase_3 PF07732.15 OWF41438.1 - 1e-38 132.0 6.9 2.6e-35 121.0 0.4 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF41438.1 - 9.7e-36 122.5 6.8 3.1e-31 107.9 0.4 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF41438.1 - 5.8e-27 94.8 1.1 1.2e-24 87.2 0.3 2.7 2 1 0 2 2 2 2 Multicopper oxidase CH PF00307.31 OWF41439.1 - 1.1e-15 57.8 0.0 2.3e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain AAA_13 PF13166.6 OWF41439.1 - 0.0018 17.0 7.5 0.003 16.3 7.5 1.3 1 0 0 1 1 1 1 AAA domain ATG16 PF08614.11 OWF41439.1 - 0.002 18.4 10.7 0.002 18.4 10.7 3.1 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) ERM PF00769.19 OWF41439.1 - 0.0022 17.9 8.5 0.0022 17.9 8.5 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family CAMSAP_CH PF11971.8 OWF41439.1 - 0.0027 17.5 0.0 0.021 14.6 0.0 2.6 3 0 0 3 3 3 1 CAMSAP CH domain SlyX PF04102.12 OWF41439.1 - 0.003 18.2 18.9 0.22 12.2 1.2 5.4 2 1 3 5 5 5 1 SlyX zf-C4H2 PF10146.9 OWF41439.1 - 0.0062 16.9 12.3 0.1 12.9 8.5 3.1 3 0 0 3 3 3 1 Zinc finger-containing protein Fez1 PF06818.15 OWF41439.1 - 0.055 13.9 18.3 0.06 13.8 6.4 3.2 2 1 1 3 3 3 0 Fez1 DUF641 PF04859.12 OWF41439.1 - 0.31 11.4 10.6 1.2 9.5 6.8 3.1 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 OWF41439.1 - 0.6 10.2 12.7 1.8 8.6 5.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 OWF41439.1 - 1 9.4 15.9 4.1 7.5 15.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OWF41439.1 - 1.2 9.7 16.3 0.39 11.2 12.7 2.2 2 0 0 2 2 1 0 Apg6 coiled-coil region HrpB7 PF09486.10 OWF41439.1 - 1.4 9.3 14.6 0.67 10.3 1.3 2.8 3 0 0 3 3 2 0 Bacterial type III secretion protein (HrpB7) Tho2 PF11262.8 OWF41439.1 - 1.8 7.7 6.9 1.6 7.9 5.4 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TolA_bind_tri PF16331.5 OWF41439.1 - 3.1 7.9 15.5 0.43 10.7 4.7 3.2 2 0 0 2 2 2 0 TolA binding protein trimerisation TMPIT PF07851.13 OWF41439.1 - 3.8 6.7 8.6 2.8 7.1 5.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein Spc7 PF08317.11 OWF41439.1 - 5.1 5.9 22.6 0.048 12.5 13.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Nsp1_C PF05064.13 OWF41439.1 - 6.3 6.6 9.6 6.7 6.6 5.9 2.8 2 1 1 3 3 3 0 Nsp1-like C-terminal region DUF4407 PF14362.6 OWF41439.1 - 8.9 5.6 14.6 0.43 9.9 6.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) FYRC PF05965.14 OWF41440.1 - 6e-20 71.2 0.0 2.4e-19 69.3 0.0 2.1 1 0 0 1 1 1 1 F/Y rich C-terminus SET PF00856.28 OWF41440.1 - 2.1e-19 70.5 0.2 2.1e-19 70.5 0.2 4.7 4 1 0 4 4 4 1 SET domain FYRN PF05964.14 OWF41440.1 - 1.9e-11 43.6 0.1 4.1e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus PHD PF00628.29 OWF41440.1 - 3.9e-11 42.7 55.1 4.2e-07 29.8 11.1 6.9 7 1 1 8 8 8 3 PHD-finger zf-CXXC PF02008.20 OWF41440.1 - 2.5e-09 37.0 18.8 2.5e-09 37.0 18.8 6.8 6 1 1 7 7 7 1 CXXC zinc finger domain zf-HC5HC2H PF13771.6 OWF41440.1 - 3.9e-09 36.6 9.3 3.9e-09 36.6 9.3 9.1 6 2 1 7 7 7 1 PHD-like zinc-binding domain Bromodomain PF00439.25 OWF41440.1 - 0.041 14.0 1.2 0.087 12.9 0.1 2.1 2 0 0 2 2 2 0 Bromodomain MFS_1 PF07690.16 OWF41441.1 - 4.7e-35 121.2 32.6 6.5e-26 91.1 1.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF41441.1 - 3.2e-09 36.6 20.4 2.3e-07 30.4 11.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB SPC25 PF06703.11 OWF41441.1 - 2.6 7.8 6.3 0.92 9.3 2.7 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Kazal_2 PF07648.15 OWF41442.1 - 2.8e-07 30.6 14.6 1.2e-05 25.3 2.3 2.3 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF41442.1 - 0.0013 18.7 5.1 0.0013 18.7 5.1 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain fn3 PF00041.21 OWF41443.1 - 1.3e-25 89.6 0.0 7.2e-09 35.9 0.0 3.2 3 0 0 3 3 3 3 Fibronectin type III domain SASA PF03629.18 OWF41444.1 - 4.3e-15 56.0 0.0 7.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase RE_SinI PF09570.10 OWF41444.1 - 0.048 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 SinI restriction endonuclease Sec8_exocyst PF04048.14 OWF41445.1 - 0.0043 17.0 0.1 0.008 16.1 0.1 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain OmpH PF03938.14 OWF41445.1 - 0.035 14.4 1.7 0.062 13.6 1.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_GP20 PF06810.11 OWF41445.1 - 0.045 13.5 1.0 0.1 12.4 0.2 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.19 OWF41445.1 - 0.11 10.4 2.9 0.14 10.0 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MetOD2 PF18548.1 OWF41445.1 - 0.11 12.6 3.1 0.4 10.8 3.1 2.0 1 1 0 1 1 1 0 Metanogen output domain 2 KxDL PF10241.9 OWF41445.1 - 0.22 11.8 3.5 0.63 10.4 3.5 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4164 PF13747.6 OWF41445.1 - 2.3 8.5 13.0 2.3 8.6 6.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Nuclease_act PF08133.11 OWF41446.1 - 0.12 12.5 0.3 0.32 11.2 0.3 1.7 1 0 0 1 1 1 0 Anticodon nuclease activator family 7tm_2 PF00002.24 OWF41447.1 - 1e-06 28.2 9.0 1.4e-06 27.8 9.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 OWF41447.1 - 1.1e-06 28.1 13.9 2.3e-06 27.0 13.9 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 OWF41447.1 - 4.9e-06 26.1 5.2 6.6e-06 25.6 5.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF373 PF04123.13 OWF41447.1 - 3.5 7.0 10.9 16 4.8 10.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF373) E1_DerP2_DerF2 PF02221.15 OWF41449.1 - 1.1e-09 38.8 0.1 1.5e-09 38.4 0.1 1.1 1 0 0 1 1 1 1 ML domain DUF1091 PF06477.13 OWF41449.1 - 0.013 15.9 0.0 0.031 14.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) AMP-binding PF00501.28 OWF41450.1 - 3e-64 217.2 0.0 3.8e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF41450.1 - 1.7e-05 25.7 0.0 4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pox_L5 PF04872.13 OWF41450.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus L5 protein family RNase_T PF00929.24 OWF41451.1 - 1.1e-26 94.4 0.0 1.2e-26 94.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 OWF41451.1 - 0.0036 17.3 0.0 0.0039 17.2 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like DAO PF01266.24 OWF41452.1 - 8.3e-23 81.5 0.0 1e-22 81.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF41452.1 - 3.2e-05 23.3 0.1 0.0009 18.6 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF41452.1 - 3.3e-05 23.2 0.1 0.043 12.9 0.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OWF41452.1 - 0.0046 16.1 0.2 2.1 7.3 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 OWF41452.1 - 0.013 15.5 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OWF41452.1 - 0.094 11.9 1.1 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pou PF00157.17 OWF41453.1 - 0.00017 21.5 1.1 2.1 8.4 0.0 3.6 1 1 3 4 4 4 2 Pou domain - N-terminal to homeobox domain SEEK1 PF15357.6 OWF41453.1 - 0.00073 19.7 0.1 1.3 9.2 0.1 3.1 1 1 1 2 2 2 2 Psoriasis susceptibility 1 candidate 1 Toast_rack_N PF17115.5 OWF41453.1 - 0.091 13.1 7.4 3.2 8.1 0.3 2.8 1 1 2 3 3 3 0 N-terminal domain of toast_rack, DUF2154 Trigger_N PF05697.13 OWF41453.1 - 0.15 12.4 6.9 2.3 8.5 0.6 2.2 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) PheRS_DBD3 PF18553.1 OWF41453.1 - 0.54 10.6 3.4 8.2 6.8 0.8 3.0 1 1 2 3 3 3 0 PheRS DNA binding domain 3 Cro PF09048.10 OWF41453.1 - 2.4 8.3 15.7 20 5.3 0.1 5.2 1 1 4 5 5 5 0 Cro Pentapeptide PF00805.22 OWF41454.1 - 1.9e-37 126.4 28.6 4.5e-13 48.6 3.2 5.2 2 2 2 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OWF41454.1 - 6.8e-23 80.6 0.5 1.2e-11 44.6 0.0 3.3 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 OWF41454.1 - 5.3e-20 71.6 0.0 9.2e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 OWF41454.1 - 3.2e-18 65.6 0.0 8.8e-07 29.0 0.0 3.8 3 1 0 3 3 3 3 Pentapeptide repeats (9 copies) KHA PF11834.8 OWF41454.1 - 7.6e-09 35.5 0.1 1.4e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel BTB_3 PF16017.5 OWF41454.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF41454.1 - 0.00038 20.7 0.0 0.0011 19.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DNA_ligase_OB PF03120.16 OWF41454.1 - 0.057 13.3 0.1 6 6.8 0.1 3.1 2 1 1 3 3 3 0 NAD-dependent DNA ligase OB-fold domain DUF348 PF03990.14 OWF41454.1 - 0.27 11.0 4.1 4.3 7.2 0.1 3.2 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain Peptidase_M17 PF00883.21 OWF41455.1 - 3.9e-120 400.8 0.2 5.6e-120 400.3 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 OWF41455.1 - 4.2e-14 52.5 0.3 6.8e-14 51.8 0.3 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Glyco_hydro_20 PF00728.22 OWF41456.1 - 6.3e-89 298.8 0.5 1e-88 298.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OWF41456.1 - 8.1e-16 58.9 0.1 2e-13 51.2 0.0 3.2 3 1 1 4 4 4 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OWF41456.1 - 0.00032 21.5 0.0 0.00069 20.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 SSF PF00474.17 OWF41457.1 - 1.3e-37 129.7 27.5 1.3e-37 129.7 27.5 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Sfi1 PF08457.10 OWF41458.1 - 4.3e-06 25.6 135.3 2e-05 23.4 30.4 6.0 1 1 5 6 6 6 4 Sfi1 spindle body protein Ig_5 PF16681.5 OWF41458.1 - 1 9.8 4.0 12 6.4 0.4 3.4 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Cu-oxidase_2 PF07731.14 OWF41460.1 - 1.1e-26 93.3 13.6 1.3e-14 54.1 5.0 6.8 5 2 0 5 5 5 5 Multicopper oxidase Cu-oxidase_3 PF07732.15 OWF41460.1 - 8.9e-21 74.1 11.6 4e-06 26.8 0.1 7.3 6 1 0 6 6 6 3 Multicopper oxidase Copper-bind PF00127.20 OWF41460.1 - 0.22 12.0 1.8 8.4 6.9 0.0 3.6 5 0 0 5 5 5 0 Copper binding proteins, plastocyanin/azurin family Ig_3 PF13927.6 OWF41461.1 - 6.3e-13 49.1 0.0 1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF41461.1 - 2.6e-10 40.2 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Kazal_1 PF00050.21 OWF41461.1 - 5.2e-07 29.6 3.4 5.2e-07 29.6 3.4 3.1 1 1 2 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF41461.1 - 5.5e-07 29.6 3.2 5.5e-07 29.6 3.2 2.3 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.6 OWF41461.1 - 1.5e-05 25.2 0.0 6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.18 OWF41461.1 - 3.2e-05 24.5 18.1 3.2e-05 24.5 18.1 2.4 2 1 0 2 2 2 1 Insulin-like growth factor binding protein ig PF00047.25 OWF41461.1 - 0.0015 18.7 0.0 0.0055 16.8 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 OWF41461.1 - 0.014 15.6 0.0 0.059 13.5 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain PDZ_6 PF17820.1 OWF41462.1 - 9.4e-07 28.6 0.0 0.00046 20.0 0.1 3.4 3 0 0 3 3 3 1 PDZ domain PH PF00169.29 OWF41462.1 - 3.3e-05 24.3 1.1 5.8e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 OWF41462.1 - 0.009 16.3 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain DUF5323 PF17257.2 OWF41462.1 - 0.018 14.9 4.5 0.075 12.9 0.1 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5323) PDZ_2 PF13180.6 OWF41462.1 - 0.034 14.5 0.3 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 PDZ domain Tricorn_PDZ PF14685.6 OWF41462.1 - 0.14 12.1 0.0 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain zf-C3HC4_2 PF13923.6 OWF41464.1 - 1.3e-08 34.6 9.2 2.4e-08 33.7 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF41464.1 - 1.4e-07 31.2 9.8 2.8e-07 30.3 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF41464.1 - 2.7e-05 24.4 9.3 5.2e-05 23.5 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF41464.1 - 0.0012 18.8 10.9 0.0036 17.2 11.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF41464.1 - 0.0016 18.3 7.6 0.0027 17.5 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41464.1 - 0.0031 17.5 6.3 0.0082 16.2 6.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DUF678 PF05077.12 OWF41464.1 - 0.0037 17.4 0.2 0.008 16.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF678) Prok-RING_4 PF14447.6 OWF41464.1 - 0.013 15.4 7.3 0.025 14.4 7.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OWF41464.1 - 0.015 15.4 4.5 0.034 14.3 4.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OWF41464.1 - 0.026 14.7 8.9 0.065 13.4 8.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OWF41464.1 - 0.038 14.3 6.6 0.083 13.2 6.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OWF41464.1 - 0.31 10.9 3.2 0.5 10.3 3.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 OWF41464.1 - 0.36 10.9 6.5 1.8 8.6 6.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon Nop PF01798.18 OWF41465.1 - 1.1e-85 286.8 0.0 1.1e-85 286.8 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OWF41465.1 - 3.8e-20 72.0 0.0 3.8e-20 72.0 0.0 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SRP-alpha_N PF04086.13 OWF41465.1 - 2.2 8.1 21.0 3.2 7.6 21.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Cdh1_DBD_1 PF18196.1 OWF41465.1 - 3.3 8.1 14.2 1.8 8.9 11.5 2.0 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DEAD PF00270.29 OWF41466.1 - 2.4e-40 138.2 0.1 4.2e-40 137.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF41466.1 - 2.4e-33 114.8 0.1 2.1e-32 111.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF41466.1 - 2e-07 31.2 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TrbI_Ftype PF09677.10 OWF41466.1 - 0.086 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) UvrD-helicase PF00580.21 OWF41466.1 - 5.8 6.3 7.8 67 2.9 7.8 2.6 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AA_permease_2 PF13520.6 OWF41468.1 - 2.4e-50 171.6 47.6 2.9e-50 171.3 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF41468.1 - 4.1e-19 68.5 48.2 2e-18 66.3 48.0 1.8 1 1 0 1 1 1 1 Amino acid permease Ank_2 PF12796.7 OWF41470.1 - 2.6e-21 76.0 0.2 6.3e-11 42.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF41470.1 - 1.3e-20 73.5 0.5 1.6e-08 34.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF41470.1 - 6.3e-16 58.2 0.1 1.5e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF41470.1 - 4.9e-11 42.6 2.2 0.0049 17.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OWF41470.1 - 1.1e-10 40.8 0.8 9.8e-05 22.5 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat ArsC PF03960.15 OWF41470.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 ArsC family SDP_N PF12278.8 OWF41470.1 - 0.52 10.4 0.0 0.52 10.4 0.0 2.5 2 1 1 3 3 3 0 Sex determination protein N terminal SepSecS PF05889.13 OWF41471.1 - 8.3e-148 492.2 0.0 1.3e-147 491.6 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 OWF41471.1 - 1.5e-06 27.7 0.0 3.2e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 OWF41471.1 - 0.0091 14.8 0.1 0.049 12.3 0.1 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 OWF41471.1 - 0.13 11.5 0.1 9.2 5.4 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 OWF41472.1 - 1.5e-06 27.4 22.5 0.0022 17.0 5.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OWF41473.1 - 3.3e-26 92.0 34.3 4.7e-26 91.5 34.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3915 PF13054.6 OWF41473.1 - 0.044 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Presenilin PF01080.17 OWF41473.1 - 0.21 10.3 5.1 0.075 11.8 1.4 1.9 2 0 0 2 2 2 0 Presenilin Neurexophilin PF06312.12 OWF41474.1 - 3e-07 30.1 0.1 5.1e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Neurexophilin SoDot-IcmSS PF16848.5 OWF41475.1 - 1.2 9.1 21.2 2.4 8.1 4.3 3.6 1 1 2 3 3 3 0 Substrate of the Dot/Icm secretion system, putative DUF3943 PF13084.6 OWF41475.1 - 2.8 7.8 28.2 6.4 6.7 4.0 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF3943) DUF4522 PF15022.6 OWF41475.1 - 3.3 8.0 13.3 32 4.8 0.3 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF4522) DUF3879 PF12995.7 OWF41475.1 - 4.7 6.9 20.8 5.4 6.7 0.5 4.6 1 1 4 5 5 5 0 Domain of unknown function, E. rectale Gene description (DUF3879) DUF3943 PF13084.6 OWF41476.1 - 0.00041 20.2 221.1 5.9 6.8 4.6 21.1 1 1 24 26 26 26 24 Domain of unknown function (DUF3943) Tetraspanin PF00335.20 OWF41477.1 - 4.5e-52 177.0 3.0 6.1e-52 176.6 3.0 1.0 1 0 0 1 1 1 1 Tetraspanin family FtsX PF02687.21 OWF41477.1 - 0.039 14.4 12.1 0.2 12.1 1.9 2.9 2 1 1 3 3 3 0 FtsX-like permease family DUF2981 PF11200.8 OWF41477.1 - 0.065 13.0 0.2 0.073 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2207 PF09972.9 OWF41477.1 - 0.11 11.3 6.5 0.15 10.8 6.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.8 OWF41477.1 - 0.18 11.9 10.4 2.4 8.3 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function Phage_holin_3_6 PF07332.11 OWF41477.1 - 0.26 11.4 3.9 0.73 9.9 3.9 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4342 PF14242.6 OWF41477.1 - 2.6 8.1 4.7 32 4.6 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) MFS_1 PF07690.16 OWF41478.1 - 1.6e-45 155.6 37.1 2.9e-37 128.4 28.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 OWF41478.1 - 0.0052 15.6 19.2 0.023 13.5 5.8 2.9 2 1 0 2 2 2 2 LacY proton/sugar symporter BT1 PF03092.16 OWF41478.1 - 0.39 8.9 6.8 0.025 12.8 1.4 1.7 2 0 0 2 2 2 0 BT1 family CPP1-like PF11833.8 OWF41478.1 - 6 6.5 5.6 2 8.0 0.7 2.4 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MIEAP PF16026.5 OWF41479.1 - 5.9e-46 157.2 0.1 5.3e-45 154.1 0.0 2.5 2 1 1 3 3 3 1 Mitochondria-eating protein HIP1_clath_bdg PF16515.5 OWF41479.1 - 0.006 17.2 2.0 0.006 17.2 2.0 2.1 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 OWF41479.1 - 0.013 15.5 2.9 0.04 14.0 2.9 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 OWF41479.1 - 0.015 14.2 1.9 0.036 13.0 1.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 OWF41479.1 - 0.016 15.0 0.2 0.057 13.3 0.2 1.9 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF3450 PF11932.8 OWF41479.1 - 0.05 12.9 0.2 0.095 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 OWF41479.1 - 0.2 11.8 4.4 0.12 12.4 2.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 OWF41479.1 - 6.7 6.8 10.9 0.65 10.1 5.9 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FAA_hydrolase PF01557.18 OWF41480.1 - 2e-68 230.3 0.0 2.6e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PAAR_motif PF05488.13 OWF41481.1 - 3.9e-07 30.2 68.9 0.1 12.8 5.6 7.8 1 1 6 8 8 8 7 PAAR motif Epiglycanin_TR PF05647.11 OWF41481.1 - 0.26 11.2 219.0 0.39 10.7 34.6 9.6 1 1 7 8 8 8 0 Tandem-repeating region of mucin, epiglycanin-like Qn_am_d_aII PF14930.6 OWF41481.1 - 1.6 9.1 19.0 26 5.2 0.2 7.4 1 1 7 9 9 9 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II PIP49_C PF12260.8 OWF41483.1 - 0.00035 20.2 0.1 0.00056 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Sortilin-Vps10 PF15902.5 OWF41484.1 - 7.7e-92 308.4 1.8 1e-91 308.0 1.8 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OWF41484.1 - 3e-36 125.3 1.8 4.7e-36 124.7 1.8 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 OWF41484.1 - 1.6e-12 47.1 11.1 3.9e-06 26.6 1.8 2.8 2 0 0 2 2 2 2 PKD domain BNR_6 PF15899.5 OWF41484.1 - 1.2e-08 34.2 3.6 0.094 12.8 0.1 5.4 5 0 0 5 5 5 3 BNR-Asp box repeat BNR PF02012.20 OWF41484.1 - 8.7e-08 31.1 20.3 0.53 10.5 0.0 7.4 6 0 0 6 6 6 4 BNR/Asp-box repeat BNR_2 PF13088.6 OWF41484.1 - 0.00031 20.2 0.8 0.069 12.4 0.0 3.4 2 1 1 3 3 3 1 BNR repeat-like domain TMEM154 PF15102.6 OWF41484.1 - 0.012 15.6 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF1180 PF06679.12 OWF41484.1 - 0.22 11.9 0.1 0.48 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Sec8_exocyst PF04048.14 OWF41485.1 - 1.2e-14 54.4 0.8 1.2e-14 54.4 0.8 2.8 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Dor1 PF04124.12 OWF41485.1 - 0.0015 17.3 3.2 0.0034 16.1 3.2 1.6 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 OWF41485.1 - 0.0016 17.8 4.7 0.0055 16.0 4.7 1.9 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Vps51 PF08700.11 OWF41485.1 - 0.0088 16.1 1.8 0.0088 16.1 1.8 3.7 3 0 0 3 3 3 1 Vps51/Vps67 AHSP PF09236.10 OWF41485.1 - 0.014 15.9 1.2 22 5.6 0.0 3.9 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein DUF1515 PF07439.11 OWF41485.1 - 0.034 14.2 0.1 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DNA_repr_REX1B PF14966.6 OWF41485.1 - 0.06 14.0 0.6 0.8 10.4 0.3 2.9 2 0 0 2 2 2 0 DNA repair REX1-B DASH_Duo1 PF08651.10 OWF41485.1 - 0.11 12.2 0.9 2.3 8.1 0.1 3.7 4 0 0 4 4 4 0 DASH complex subunit Duo1 HBM PF16591.5 OWF41485.1 - 0.12 11.8 1.6 1.3 8.3 0.0 3.0 2 1 1 3 3 3 0 Helical bimodular sensor domain DUF4200 PF13863.6 OWF41485.1 - 0.36 11.2 4.9 0.8 10.1 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) COG2 PF06148.11 OWF41485.1 - 0.63 10.1 5.8 9.2 6.4 0.9 4.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Rhomboid PF01694.22 OWF41486.1 - 5.1e-20 72.0 9.8 1.2e-19 70.8 9.8 1.6 1 0 0 1 1 1 1 Rhomboid family Pex24p PF06398.11 OWF41486.1 - 0.059 12.3 0.6 0.18 10.7 0.6 1.8 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Lectin_C PF00059.21 OWF41489.1 - 4.3e-53 178.6 22.7 1.6e-13 51.4 2.8 4.2 4 0 0 4 4 4 4 Lectin C-type domain UL45 PF05473.12 OWF41489.1 - 0.048 13.3 14.4 0.18 11.4 0.0 4.6 4 2 0 4 4 4 0 UL45 protein, carbohydrate-binding C-type lectin-like Intimin_C PF07979.11 OWF41489.1 - 4 7.9 7.8 21 5.6 0.1 3.5 4 0 0 4 4 4 0 Intimin C-type lectin domain Reeler PF02014.16 OWF41490.1 - 6.6e-27 94.8 0.5 1.6e-26 93.5 0.5 1.7 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 OWF41490.1 - 6.5e-15 55.4 2.0 1.2e-14 54.6 2.0 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 OWF41490.1 - 1.5e-09 38.1 7.9 1.5e-09 38.1 7.9 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF679 PF05078.12 OWF41490.1 - 0.055 13.4 1.4 0.1 12.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF679) Homeodomain PF00046.29 OWF41491.1 - 1.4e-20 72.9 3.8 2.5e-20 72.1 3.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF41491.1 - 0.089 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Toprim_N PF08275.11 OWF41493.1 - 0.073 13.1 0.1 0.073 13.1 0.1 2.9 2 1 1 3 3 3 0 DNA primase catalytic core, N-terminal domain SCVP PF17619.2 OWF41493.1 - 2 9.3 5.3 3.3 8.6 0.3 3.4 2 1 1 3 3 3 0 Secreted clade V proteins Lectin_C PF00059.21 OWF41494.1 - 2.4e-13 50.8 0.0 3.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF41494.1 - 6e-06 26.1 0.3 6e-06 26.1 0.3 1.6 2 0 0 2 2 2 1 PAN domain Adipokin_hormo PF06377.11 OWF41495.1 - 2.1e-08 34.4 41.1 1.3 9.4 0.1 9.1 8 1 0 8 8 8 7 Adipokinetic hormone TRH PF05438.12 OWF41495.1 - 0.69 9.6 2.9 5 6.8 0.3 2.3 1 1 1 2 2 2 0 Thyrotropin-releasing hormone (TRH) Mab-21 PF03281.14 OWF41496.1 - 4.7e-29 101.6 0.0 6.7e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF41496.1 - 0.01 16.1 0.0 4 7.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF41496.1 - 0.031 14.4 0.0 10 6.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF41496.1 - 0.047 13.9 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 YqbF PF14553.6 OWF41496.1 - 0.079 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 YqbF, hypothetical protein domain RNase_P_p30 PF01876.16 OWF41497.1 - 7.1e-53 179.3 0.4 1e-52 178.8 0.4 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Glyco_transf_7C PF02709.14 OWF41498.1 - 1.8e-26 91.6 0.1 3.5e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 OWF41498.1 - 6.9e-23 80.8 0.0 1.1e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 OWF41498.1 - 9.9e-05 21.9 0.5 0.0016 17.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 An_peroxidase PF03098.15 OWF41499.1 - 6.8e-182 605.7 0.4 8.5e-182 605.4 0.4 1.1 1 0 0 1 1 1 1 Animal haem peroxidase DTC PF18102.1 OWF41499.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Deltex C-terminal domain Fibrinogen_C PF00147.18 OWF41500.1 - 6.3e-08 32.7 0.0 6.6e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Homeodomain PF00046.29 OWF41501.1 - 1.1e-20 73.2 2.4 2.3e-20 72.2 2.4 1.6 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 OWF41501.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 OWF41501.1 - 0.0021 17.5 0.1 0.0053 16.2 0.1 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF41501.1 - 0.0094 15.8 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4685 PF15737.5 OWF41501.1 - 2.1 8.8 6.4 1.3 9.5 1.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4685) DUF872 PF05915.12 OWF41502.1 - 1.4e-17 63.9 0.3 1.5e-17 63.8 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) YrhK PF14145.6 OWF41502.1 - 0.053 13.4 0.2 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 YrhK-like protein DUF3040 PF11239.8 OWF41502.1 - 0.1 12.9 0.8 0.17 12.2 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Neurensin PF14927.6 OWF41502.1 - 0.16 11.7 0.3 0.36 10.5 0.3 1.8 1 1 0 1 1 1 0 Neurensin Saf_2TM PF18303.1 OWF41502.1 - 1.4 8.5 5.3 1.7 8.2 1.6 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain START PF01852.19 OWF41503.1 - 8.2e-19 67.8 0.3 1.3e-18 67.2 0.3 1.2 1 0 0 1 1 1 1 START domain PTN13_u3 PF16599.5 OWF41503.1 - 0.029 14.4 0.3 0.059 13.4 0.3 1.5 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ Fibrinogen_C PF00147.18 OWF41504.1 - 4.8e-55 186.8 7.5 5.4e-55 186.6 7.5 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4400 PF14348.6 OWF41505.1 - 0.073 12.6 0.6 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) PKcGMP_CC PF16808.5 OWF41505.1 - 4.8 7.1 12.5 0.069 13.0 1.9 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ndr PF03096.14 OWF41506.1 - 6.2e-57 192.4 0.0 7.1e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 OWF41506.1 - 0.062 12.9 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold MGAT2 PF05060.14 OWF41507.1 - 2.2e-147 490.7 11.8 2.8e-147 490.4 11.8 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) YqgF PF14639.6 OWF41507.1 - 0.25 11.1 1.4 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 SRP_TPR_like PF17004.5 OWF41508.1 - 4.2e-25 88.1 4.0 4.2e-25 88.1 4.0 3.1 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_19 PF14559.6 OWF41508.1 - 4.5e-15 55.9 22.3 0.01 16.3 0.4 7.9 4 2 4 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF41508.1 - 6.6e-13 48.7 20.3 0.00028 21.0 2.3 6.4 4 3 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SRP72 PF08492.12 OWF41508.1 - 9.5e-13 48.4 6.7 9.5e-13 48.4 6.7 3.2 3 0 0 3 3 2 1 SRP72 RNA-binding domain TPR_14 PF13428.6 OWF41508.1 - 3.3e-12 46.1 11.5 0.62 11.0 0.0 7.9 5 2 4 9 9 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF41508.1 - 3.2e-10 40.2 12.8 0.0016 18.7 0.0 6.7 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF41508.1 - 8.1e-08 31.8 24.3 0.02 15.0 0.0 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF41508.1 - 3.1e-07 30.9 16.3 0.15 12.8 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 OWF41508.1 - 1.6e-06 28.2 0.1 0.14 12.9 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OWF41508.1 - 4e-06 26.5 2.1 0.78 9.4 0.0 4.7 4 1 1 5 5 5 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 OWF41508.1 - 4.3e-05 23.9 20.5 4 8.3 0.0 9.0 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF41508.1 - 7.1e-05 22.9 4.6 0.45 10.7 0.1 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 OWF41508.1 - 0.00028 21.4 5.8 8 6.9 3.8 3.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 OWF41508.1 - 0.00028 20.6 23.1 0.014 15.1 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_5 PF12688.7 OWF41508.1 - 0.0016 18.7 3.1 0.13 12.5 0.0 3.7 3 1 0 4 4 4 1 Tetratrico peptide repeat PPR PF01535.20 OWF41508.1 - 0.0021 18.2 0.6 37 4.9 0.0 6.2 8 0 0 8 8 6 0 PPR repeat TPR_8 PF13181.6 OWF41508.1 - 0.0051 16.9 15.3 0.39 11.1 0.0 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat XPC-binding PF09280.11 OWF41508.1 - 0.0072 16.0 0.7 0.022 14.5 0.7 1.9 1 0 0 1 1 1 1 XPC-binding domain TPR_MalT PF17874.1 OWF41508.1 - 0.014 14.8 15.5 0.039 13.3 2.6 4.2 3 2 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 OWF41508.1 - 0.018 14.9 9.0 0.35 10.8 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PknG_TPR PF16918.5 OWF41508.1 - 0.03 13.1 0.5 5.2 5.7 0.1 2.7 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat YfiO PF13525.6 OWF41508.1 - 0.089 12.5 4.2 3 7.5 0.1 3.2 3 1 0 3 3 3 0 Outer membrane lipoprotein TPR_11 PF13414.6 OWF41508.1 - 0.23 11.2 5.5 19 5.1 0.0 4.9 5 0 0 5 5 5 0 TPR repeat p25-alpha PF05517.12 OWF41508.1 - 0.48 10.6 6.4 0.18 12.0 2.7 2.2 2 0 0 2 2 2 0 p25-alpha Wzy_C_2 PF11846.8 OWF41508.1 - 0.79 9.6 4.9 29 4.5 0.0 4.0 4 1 1 5 5 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 OWF41508.1 - 1.2 9.4 6.2 9 6.6 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF41508.1 - 3.8 8.1 8.3 73 4.1 0.0 5.8 7 0 0 7 7 4 0 Tetratricopeptide repeat AnkUBD PF18418.1 OWF41509.1 - 5e-30 103.5 0.0 1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin ubiquitin-binding domain OTU PF02338.19 OWF41509.1 - 7.7e-29 100.8 0.0 1.6e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 OWF41509.1 - 7.8e-11 41.1 31.7 0.00018 20.7 1.4 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Copper-fist PF00649.18 OWF41509.1 - 3.6 7.2 13.1 2.2 7.8 0.7 3.7 3 0 0 3 3 3 0 Copper fist DNA binding domain PH PF00169.29 OWF41510.1 - 1.7e-16 60.6 0.5 1.7e-16 60.6 0.5 2.0 2 0 0 2 2 2 1 PH domain SH2 PF00017.24 OWF41510.1 - 1.4e-06 28.3 0.1 3.7e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SIN1_PH PF16979.5 OWF41510.1 - 0.0054 17.0 0.1 0.061 13.6 0.0 2.6 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PH_9 PF15410.6 OWF41510.1 - 0.0066 16.8 0.1 0.97 9.8 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Trypan_PARP PF05887.11 OWF41510.1 - 0.83 9.6 22.2 0.024 14.6 13.0 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Gly_acyl_tr_N PF06021.11 OWF41511.1 - 1.1e-16 61.5 0.0 3.3e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Gly_acyl_tr_C PF08444.10 OWF41511.1 - 2.3e-05 24.5 0.3 5.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FR47 PF08445.10 OWF41511.1 - 0.0017 18.3 0.0 0.0052 16.7 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Ank_2 PF12796.7 OWF41512.1 - 2.7e-42 143.2 2.2 1.6e-16 60.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF41512.1 - 1.7e-30 104.7 2.5 2.8e-10 40.2 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF41512.1 - 1.8e-26 91.4 0.4 0.00033 21.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OWF41512.1 - 2.6e-26 91.6 3.6 4.9e-06 27.0 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41512.1 - 2.6e-23 79.6 0.2 0.0021 18.4 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat PhoD_N PF16655.5 OWF41512.1 - 0.05 14.1 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OWF41512.1 - 0.059 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Sarcoglycan_2 PF05510.13 OWF41513.1 - 1.5e-05 24.0 0.0 1.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon TMEM154 PF15102.6 OWF41513.1 - 0.00011 22.1 0.7 0.00014 21.7 0.1 1.5 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 OWF41513.1 - 0.0021 18.9 0.9 0.0043 17.9 0.9 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 OWF41513.1 - 0.0035 17.3 0.4 0.0035 17.3 0.4 1.6 2 0 0 2 2 2 1 Transmembrane 52 PAG PF15347.6 OWF41513.1 - 0.013 14.5 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Shisa PF13908.6 OWF41513.1 - 0.047 13.9 0.2 0.078 13.2 0.1 1.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Comm PF15957.5 OWF41513.1 - 0.088 13.2 0.2 0.23 11.8 0.2 1.8 1 1 0 1 1 1 0 Commissureless WBP-1 PF11669.8 OWF41513.1 - 0.095 13.3 2.5 0.24 12.0 2.5 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 DAG1 PF05454.11 OWF41513.1 - 0.12 11.7 1.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RCR PF12273.8 OWF41513.1 - 2.3 8.9 6.7 11 6.6 6.7 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red LIM_bind PF01803.16 OWF41514.1 - 2.9e-58 197.3 2.1 8.4e-45 153.2 0.4 2.3 1 1 1 2 2 2 2 LIM-domain binding protein LID PF17916.1 OWF41514.1 - 1.6e-17 62.9 2.3 2.8e-17 62.0 2.3 1.4 1 0 0 1 1 1 1 LIM interaction domain (LID) DUF1180 PF06679.12 OWF41514.1 - 0.42 11.0 0.1 0.42 11.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Vpu PF00558.19 OWF41514.1 - 0.53 10.1 2.6 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Vpu protein Tae4 PF14113.6 OWF41515.1 - 6.4e-11 42.5 0.0 8.9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase effector protein 4 Tae4 PF14113.6 OWF41516.1 - 6.4e-08 32.9 0.0 9.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase effector protein 4 ANAPC4 PF12896.7 OWF41517.1 - 8.5e-58 195.2 3.9 1.3e-57 194.6 3.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 OWF41517.1 - 2.1e-26 92.0 0.1 4.7e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF41517.1 - 0.11 13.4 0.0 1.5 9.9 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat RhoGAP PF00620.27 OWF41518.1 - 9.3e-30 103.5 1.7 1.9e-29 102.5 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain DUF5532 PF17673.1 OWF41518.1 - 0.0058 16.7 0.3 0.018 15.1 0.3 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5532) Cornichon PF03311.14 OWF41520.1 - 0.11 12.8 17.6 0.17 12.2 7.2 3.1 1 1 2 3 3 3 0 Cornichon protein NqrM PF04400.13 OWF41521.1 - 0.0097 15.6 0.9 0.019 14.7 0.9 1.4 1 0 0 1 1 1 1 (Na+)-NQR maturation NqrM NHL PF01436.21 OWF41521.1 - 0.012 15.6 4.2 4.5 7.5 0.0 3.8 4 0 0 4 4 4 0 NHL repeat HLH PF00010.26 OWF41522.1 - 4.4e-06 26.6 0.4 4.4e-06 26.6 0.4 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Adeno_terminal PF02459.15 OWF41522.1 - 0.26 9.6 0.8 0.33 9.3 0.0 1.5 2 0 0 2 2 2 0 Adenoviral DNA terminal protein CUE PF02845.16 OWF41523.1 - 0.00014 21.5 0.6 63 3.4 0.0 7.7 6 2 3 9 9 9 0 CUE domain Tcp10_C PF07202.13 OWF41523.1 - 0.00027 20.9 30.6 1.5 8.7 10.0 5.0 1 1 3 4 4 4 4 T-complex protein 10 C-terminus DUF4573 PF15140.6 OWF41523.1 - 0.00037 20.3 0.0 0.42 10.4 0.0 3.2 1 1 2 4 4 4 2 Domain of unknown function (DUF4573) DUF4516 PF14990.6 OWF41524.1 - 0.047 13.4 1.3 1.4 8.7 0.2 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4516) HTH_51 PF18558.1 OWF41525.1 - 0.00077 19.3 0.1 25 4.8 0.0 4.0 1 1 4 5 5 5 4 Helix-turn-helix domain FLYWCH PF04500.16 OWF41527.1 - 8.4e-07 29.0 4.8 1.5e-06 28.2 4.8 1.4 1 0 0 1 1 1 1 FLYWCH zinc finger domain AIG1 PF04548.16 OWF41528.1 - 2.2e-33 115.4 0.6 2.2e-33 115.4 0.6 1.6 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.23 OWF41528.1 - 0.0041 17.2 0.8 0.3 11.1 0.0 2.5 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF41528.1 - 0.0051 16.9 0.9 0.026 14.6 0.0 2.5 2 2 0 2 2 2 1 50S ribosome-binding GTPase SepF PF04472.12 OWF41528.1 - 0.013 15.7 2.0 0.21 11.9 0.1 3.1 2 1 1 3 3 3 0 Cell division protein SepF N6_N4_Mtase PF01555.18 OWF41528.1 - 0.029 14.1 0.8 0.039 13.6 0.8 1.3 1 0 0 1 1 1 0 DNA methylase DUF3369 PF11849.8 OWF41528.1 - 0.08 13.1 0.3 0.15 12.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) DUF4225 PF13988.6 OWF41528.1 - 0.081 12.5 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) AIG1 PF04548.16 OWF41529.1 - 3.9e-54 183.2 0.2 6e-54 182.6 0.2 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF41529.1 - 5.8e-07 29.6 0.4 1.2e-06 28.5 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OWF41529.1 - 0.076 13.1 3.4 0.15 12.1 0.1 2.6 2 1 1 3 3 3 0 Dynamin family Peripla_BP_2 PF01497.18 OWF41529.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein Sipho_Gp157 PF05565.11 OWF41529.1 - 0.11 12.5 1.5 0.16 12.0 0.9 1.6 2 0 0 2 2 2 0 Siphovirus Gp157 AIG1 PF04548.16 OWF41530.1 - 3.2e-49 167.1 0.4 4.9e-49 166.5 0.4 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF41530.1 - 2.8e-10 40.3 0.0 7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OWF41530.1 - 7.8e-06 26.0 5.3 0.0011 19.1 0.6 3.1 2 2 1 3 3 3 2 Dynamin family Septin PF00735.18 OWF41530.1 - 0.00011 21.6 0.2 0.00011 21.6 0.2 2.3 3 0 0 3 3 3 1 Septin RsgA_GTPase PF03193.16 OWF41530.1 - 0.0011 18.9 1.1 0.0025 17.7 0.1 2.1 3 0 0 3 3 3 1 RsgA GTPase Prominin PF05478.11 OWF41530.1 - 0.0028 15.7 1.4 0.0091 14.0 0.4 1.8 2 0 0 2 2 2 1 Prominin ABC_tran PF00005.27 OWF41530.1 - 0.0052 17.3 0.2 0.049 14.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Ubiq_cyt_C_chap PF03981.12 OWF41530.1 - 0.0053 16.8 0.3 0.15 12.1 0.1 2.3 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Sipho_Gp157 PF05565.11 OWF41530.1 - 0.0074 16.3 2.0 0.0082 16.2 0.8 1.7 2 0 0 2 2 2 1 Siphovirus Gp157 Ras PF00071.22 OWF41530.1 - 0.015 14.9 0.6 0.09 12.4 0.2 2.4 2 1 0 2 2 2 0 Ras family Torsin PF06309.11 OWF41530.1 - 0.016 15.3 0.1 0.25 11.5 0.0 2.5 2 1 0 2 2 2 0 Torsin KASH_CCD PF14662.6 OWF41530.1 - 0.026 14.4 4.2 0.026 14.4 2.3 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 OWF41530.1 - 0.048 12.3 2.2 0.078 11.6 2.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OWF41530.1 - 0.057 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OWF41530.1 - 0.072 13.4 0.4 0.17 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain GED PF02212.18 OWF41530.1 - 0.081 13.1 1.3 0.25 11.5 0.6 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF1664 PF07889.12 OWF41530.1 - 0.28 11.2 4.8 1.8 8.6 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 OWF41530.1 - 1 9.8 6.7 0.59 10.6 3.8 2.0 2 0 0 2 2 2 0 Cell division protein ZapB GTP-bdg_M PF16360.5 OWF41530.1 - 5.1 7.8 7.5 3.6 8.2 2.7 2.8 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region DUF4147 PF13660.6 OWF41532.1 - 1.7e-70 237.2 0.3 4.3e-70 235.8 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 OWF41532.1 - 2.4e-33 114.6 1.8 2.4e-33 114.6 1.8 1.8 2 0 0 2 2 2 1 MOFRL family WD40 PF00400.32 OWF41533.1 - 3.8e-20 71.8 4.0 0.00015 22.5 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF41533.1 - 1.7e-11 44.3 0.0 0.0069 16.7 0.0 5.0 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF41533.1 - 0.057 12.1 0.0 5.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 OWF41533.1 - 0.083 12.9 0.1 10 6.2 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PP2C PF00481.21 OWF41534.1 - 2.4e-32 112.6 0.0 3.3e-17 63.0 0.0 3.1 2 2 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 OWF41534.1 - 1.4e-05 25.1 0.0 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF1751 PF08551.10 OWF41535.1 - 1.7e-28 99.1 5.4 4.3e-28 97.8 5.4 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OWF41535.1 - 0.00019 21.4 10.0 0.00019 21.4 10.0 1.8 2 0 0 2 2 2 1 Rhomboid family Ras PF00071.22 OWF41536.1 - 2.5e-46 157.2 0.2 3e-46 157.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF41536.1 - 5.2e-32 110.6 0.3 8e-32 110.0 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF41536.1 - 3.3e-14 52.7 0.4 4.7e-14 52.2 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF41536.1 - 2e-06 27.4 0.3 2.4e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF41536.1 - 2.8e-05 24.2 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF41536.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OWF41536.1 - 0.0034 17.2 0.6 0.18 11.5 0.3 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OWF41536.1 - 0.0041 16.7 0.0 0.038 13.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OWF41536.1 - 0.064 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 OWF41536.1 - 0.066 13.8 0.1 13 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 OWF41538.1 - 1.7e-41 140.7 2.2 3.1e-17 62.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) CCDC144C PF14915.6 OWF41538.1 - 4e-39 134.5 51.0 4e-39 134.5 51.0 8.4 2 1 4 8 8 8 1 CCDC144C protein coiled-coil region Ank_5 PF13857.6 OWF41538.1 - 6.7e-30 102.8 1.7 3.7e-09 36.7 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF41538.1 - 1.1e-27 95.2 0.5 1.6e-05 25.1 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OWF41538.1 - 5e-26 90.7 0.0 1.3e-10 41.6 0.0 5.1 2 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41538.1 - 4.5e-22 75.8 0.1 0.0028 18.0 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat MARVEL PF01284.23 OWF41540.1 - 4.8e-33 114.2 6.0 6e-33 113.9 6.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Chol_subst-bind PF09129.11 OWF41540.1 - 0.011 14.7 0.9 0.017 14.1 0.9 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Docking PF08990.11 OWF41541.1 - 3.7e-10 39.2 101.0 0.3 10.7 1.0 22.1 14 4 3 24 24 24 3 Erythronolide synthase docking Cnn_1N PF07989.11 OWF41541.1 - 3.4e-05 23.9 32.0 2 8.6 0.9 9.0 1 1 8 9 9 9 1 Centrosomin N-terminal motif 1 DUF948 PF06103.11 OWF41541.1 - 3.9e-05 23.8 45.4 7.2 6.9 0.8 10.6 1 1 9 10 10 10 3 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 OWF41541.1 - 5.1e-05 23.8 36.0 0.32 11.6 3.3 6.5 1 1 3 4 4 4 1 Syntaxin 6, N-terminal DUF2680 PF10925.8 OWF41541.1 - 0.00086 19.3 27.8 92 3.2 0.1 13.5 4 3 13 17 17 17 0 Protein of unknown function (DUF2680) Mod_r PF07200.13 OWF41541.1 - 0.0025 17.9 8.2 5.8 7.0 0.8 4.8 1 1 5 6 6 6 2 Modifier of rudimentary (Mod(r)) protein OEP PF02321.18 OWF41541.1 - 0.061 13.1 17.7 0.25 11.1 0.7 4.7 1 1 3 4 4 4 0 Outer membrane efflux protein AATF-Che1 PF13339.6 OWF41541.1 - 0.081 13.6 15.7 2e+02 2.6 2.8 7.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor ATG16 PF08614.11 OWF41541.1 - 0.56 10.4 32.7 3.9 7.7 3.9 4.3 1 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 OWF41541.1 - 0.97 8.5 23.2 4.6 6.2 7.3 3.5 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 OWF41541.1 - 1.5 9.6 11.4 31 5.3 0.1 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) SlyX PF04102.12 OWF41541.1 - 3.7 8.2 55.2 6.7 7.4 2.1 8.9 1 1 7 8 8 8 0 SlyX CorA PF01544.18 OWF41541.1 - 4.2 6.6 83.8 3.8 6.7 7.5 9.1 1 1 6 7 7 6 0 CorA-like Mg2+ transporter protein Vps51 PF08700.11 OWF41541.1 - 5 7.3 40.3 5 7.3 1.3 7.8 1 1 10 11 11 11 0 Vps51/Vps67 CBM_14 PF01607.24 OWF41542.1 - 8.7e-05 22.6 7.4 8.7e-05 22.6 7.4 1.9 2 1 0 2 2 2 1 Chitin binding Peritrophin-A domain Amnionless PF14828.6 OWF41542.1 - 0.00079 18.4 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Amnionless FAM163 PF15069.6 OWF41542.1 - 0.0037 17.7 0.0 0.0077 16.7 0.0 1.5 1 0 0 1 1 1 1 FAM163 family EphA2_TM PF14575.6 OWF41542.1 - 0.005 17.7 0.3 0.0075 17.1 0.3 1.5 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4006 PF13179.6 OWF41542.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF4006) Chordopox_A13L PF05961.11 OWF41542.1 - 0.029 14.6 0.7 0.087 13.1 0.5 2.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein SIT PF15330.6 OWF41542.1 - 0.034 14.6 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT EVC2_like PF12297.8 OWF41542.1 - 0.06 12.0 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein ECSCR PF15820.5 OWF41542.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator MLANA PF14991.6 OWF41542.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DUF2746 PF10874.8 OWF41542.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) CD34_antigen PF06365.12 OWF41542.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family S1FA PF04689.13 OWF41542.1 - 0.12 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA Herpes_LMP1 PF05297.11 OWF41542.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EzrA PF06160.12 OWF41542.1 - 0.15 10.2 0.1 0.2 9.8 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SKG6 PF08693.10 OWF41542.1 - 0.84 9.1 6.8 1.5 8.2 6.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-RING_UBOX PF13445.6 OWF41544.1 - 7.1e-11 42.0 5.9 7.1e-11 42.0 5.9 3.7 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF41544.1 - 3.9e-08 33.0 7.6 3.9e-08 33.0 7.6 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF41544.1 - 7.7e-08 32.5 7.2 7.7e-08 32.5 7.2 3.8 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF41544.1 - 1.3e-07 31.6 9.4 1.3e-07 31.6 9.4 3.4 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF41544.1 - 2.6e-07 30.4 5.0 2.6e-07 30.4 5.0 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF41544.1 - 5.5e-07 29.4 6.7 5.5e-07 29.4 6.7 3.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-B_box PF00643.24 OWF41544.1 - 2.5e-05 24.4 5.0 2.5e-05 24.4 5.0 4.2 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.6 OWF41544.1 - 3.1e-05 23.7 10.2 3.1e-05 23.7 10.2 4.0 4 2 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Syntaxin_2 PF14523.6 OWF41544.1 - 0.0016 18.7 2.5 0.0036 17.6 2.5 1.6 1 0 0 1 1 1 1 Syntaxin-like protein Prok-RING_4 PF14447.6 OWF41544.1 - 0.0025 17.6 10.5 0.0025 17.6 10.5 3.3 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 HSCB_C PF07743.13 OWF41544.1 - 0.013 16.0 2.1 0.029 14.9 1.1 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain zf-Nse PF11789.8 OWF41544.1 - 0.073 12.9 6.7 0.098 12.5 5.3 1.9 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Baculo_PEP_C PF04513.12 OWF41544.1 - 0.082 12.9 1.3 0.13 12.3 1.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_UBOX PF13445.6 OWF41545.1 - 2.1e-11 43.7 4.4 2.1e-11 43.7 4.4 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF41545.1 - 8.7e-08 31.9 7.9 8.7e-08 31.9 7.9 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF41545.1 - 8.8e-08 32.2 9.3 8.8e-08 32.2 9.3 3.4 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF41545.1 - 1.2e-07 31.9 7.2 1.2e-07 31.9 7.2 4.0 3 1 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF41545.1 - 1.4e-06 28.1 6.9 1.4e-06 28.1 6.9 3.3 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF41545.1 - 2.6e-06 27.2 5.0 2.6e-06 27.2 5.0 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF41545.1 - 3.2e-05 23.7 10.5 3.2e-05 23.7 10.5 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF41545.1 - 8.8e-05 22.6 5.0 8.8e-05 22.6 5.0 4.6 5 1 0 5 5 4 1 B-box zinc finger Syntaxin_2 PF14523.6 OWF41545.1 - 0.0017 18.7 4.9 0.0052 17.1 4.9 1.9 1 0 0 1 1 1 1 Syntaxin-like protein HSCB_C PF07743.13 OWF41545.1 - 0.0053 17.2 5.2 0.18 12.4 0.3 2.4 1 1 1 2 2 2 2 HSCB C-terminal oligomerisation domain zf-Nse PF11789.8 OWF41545.1 - 0.0066 16.3 3.6 0.023 14.5 3.6 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OWF41545.1 - 0.019 14.8 11.8 0.079 12.8 9.4 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Thioredoxin_13 PF18401.1 OWF41545.1 - 0.11 12.4 0.3 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain SGL PF08450.12 OWF41545.1 - 0.11 12.0 0.5 0.79 9.3 0.0 2.4 2 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region ALMT PF11744.8 OWF41545.1 - 0.2 10.5 2.1 0.38 9.5 2.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 OWF41545.1 - 0.46 10.0 3.3 0.8 9.2 3.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_10 PF16685.5 OWF41545.1 - 6.7 6.9 17.3 2.8 8.2 1.6 4.0 2 2 1 3 3 3 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 OWF41546.1 - 1.3e-09 38.0 6.5 1.3e-09 38.0 6.5 2.9 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF41546.1 - 3.9e-07 30.1 6.5 3.9e-07 30.1 6.5 3.6 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF41546.1 - 1.4e-06 28.0 6.1 1.4e-06 28.0 6.1 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF41546.1 - 1.6e-06 27.8 5.3 1.6e-06 27.8 5.3 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF41546.1 - 5e-06 26.3 4.2 5e-06 26.3 4.2 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OWF41546.1 - 6.9e-05 22.6 1.6 6.9e-05 22.6 1.6 2.8 3 0 0 3 3 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OWF41546.1 - 0.00017 21.9 5.7 0.00017 21.9 5.7 3.6 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OWF41546.1 - 0.00019 21.3 3.7 0.00019 21.3 3.7 3.9 4 0 0 4 4 4 1 zinc-RING finger domain U-box PF04564.15 OWF41546.1 - 0.029 14.5 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 U-box domain Tektin PF03148.14 OWF41546.1 - 0.089 11.5 4.5 0.13 11.0 4.5 1.1 1 0 0 1 1 1 0 Tektin family Golgin_A5 PF09787.9 OWF41546.1 - 0.37 10.2 7.3 0.47 9.9 6.5 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 CEBP_ZZ PF16366.5 OWF41546.1 - 7 7.0 15.0 0.54 10.5 4.7 3.1 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RtcB PF01139.17 OWF41547.1 - 2.5e-147 491.3 0.2 2.9e-147 491.1 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Kp4 PF09044.10 OWF41547.1 - 0.14 12.2 1.2 0.38 10.9 0.6 2.0 2 0 0 2 2 2 0 Kp4 Lyase_aromatic PF00221.19 OWF41548.1 - 4.5e-194 645.4 0.0 5.4e-194 645.2 0.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 OWF41548.1 - 6.2e-10 39.2 0.2 3.2e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 N-terminal of Par3 and HAL proteins Asp_Glu_race_2 PF14669.6 OWF41548.1 - 0.053 13.2 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative aspartate racemase Alpha-E PF04168.12 OWF41548.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Aminotran_1_2 PF00155.21 OWF41549.1 - 8.3e-52 176.5 0.0 1.1e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 OWF41550.1 - 5.8e-50 170.5 0.0 6.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cadherin PF00028.17 OWF41551.1 - 4.2e-187 607.3 82.0 1.1e-23 83.4 0.5 13.2 13 0 0 13 13 13 13 Cadherin domain Cadherin_3 PF16184.5 OWF41551.1 - 1.5e-24 86.1 41.2 0.0011 18.9 0.0 12.3 12 2 0 13 13 13 10 Cadherin-like Cadherin_2 PF08266.12 OWF41551.1 - 4.7e-09 36.0 0.0 5.8 6.8 0.0 8.4 11 0 0 11 11 11 3 Cadherin-like Big_9 PF17963.1 OWF41551.1 - 0.0021 18.7 11.6 0.0021 18.7 11.6 13.6 12 2 1 13 13 13 4 Bacterial Ig domain Cadherin PF00028.17 OWF41552.1 - 1.8e-51 172.6 9.1 1.6e-24 86.1 0.4 4.1 4 0 0 4 4 4 4 Cadherin domain Cadherin_3 PF16184.5 OWF41552.1 - 7.4e-15 54.9 0.4 0.00052 20.0 0.0 3.7 3 1 0 3 3 3 3 Cadherin-like Cadherin PF00028.17 OWF41553.1 - 5.6e-241 780.0 109.6 1e-20 74.0 0.6 17.2 17 0 0 17 17 17 17 Cadherin domain Cadherin_3 PF16184.5 OWF41553.1 - 2.1e-32 111.4 46.5 0.022 14.8 0.1 15.3 15 1 0 15 15 15 12 Cadherin-like Cadherin_2 PF08266.12 OWF41553.1 - 1.1e-19 70.0 0.0 0.45 10.4 0.0 11.8 13 1 0 13 13 13 6 Cadherin-like Big_9 PF17963.1 OWF41553.1 - 0.01 16.5 13.0 0.01 16.5 13.0 17.3 16 1 1 17 17 17 0 Bacterial Ig domain Stn1 PF10451.9 OWF41553.1 - 0.62 9.0 3.1 22 3.9 0.1 4.1 5 0 0 5 5 5 0 Telomere regulation protein Stn1 hNIFK_binding PF12196.8 OWF41553.1 - 9.4 5.8 7.4 6.2 6.4 0.2 3.7 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Pkinase_Tyr PF07714.17 OWF41554.1 - 1.6e-88 296.4 0.0 3e-88 295.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF41554.1 - 6.3e-37 127.4 0.0 1e-36 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sema PF01403.19 OWF41554.1 - 1.8e-36 125.9 0.4 2.9e-36 125.2 0.4 1.3 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 OWF41554.1 - 4.6e-32 110.0 19.8 6.3e-11 42.2 0.2 5.5 5 1 0 5 5 5 4 IPT/TIG domain PSI PF01437.25 OWF41554.1 - 2.8e-06 27.7 10.6 7.8e-06 26.3 10.6 1.8 1 0 0 1 1 1 1 Plexin repeat YabP PF07873.11 OWF41554.1 - 0.061 13.1 5.4 11 5.9 0.0 4.3 4 0 0 4 4 4 0 YabP family Insulin_TMD PF17870.1 OWF41554.1 - 2.5 8.2 8.0 6.9 6.8 8.0 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Amnionless PF14828.6 OWF41554.1 - 5.6 5.7 7.1 11 4.7 0.0 2.2 2 0 0 2 2 2 0 Amnionless Pkinase_Tyr PF07714.17 OWF41556.1 - 5.1e-89 298.0 0.0 8.2e-89 297.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF41556.1 - 7.8e-38 130.3 0.0 1.3e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 OWF41556.1 - 2.4e-33 114.1 20.7 4.8e-12 45.8 0.2 5.4 5 1 0 5 5 5 4 IPT/TIG domain Sema PF01403.19 OWF41556.1 - 4.3e-33 114.8 0.5 6.8e-33 114.1 0.5 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 OWF41556.1 - 7.9e-06 26.3 9.9 1.7e-05 25.2 9.9 1.6 1 0 0 1 1 1 1 Plexin repeat Pkinase_Tyr PF07714.17 OWF41557.1 - 2.7e-91 305.4 0.0 5.6e-91 304.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OWF41557.1 - 1.3e-42 146.0 0.0 2.6e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 OWF41557.1 - 7.1e-29 99.7 20.8 8.8e-10 38.5 2.4 4.6 4 0 0 4 4 4 4 IPT/TIG domain Sema PF01403.19 OWF41557.1 - 3.1e-22 79.0 0.1 5.7e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 OWF41557.1 - 0.00038 20.9 14.6 0.0014 19.2 14.6 2.0 1 0 0 1 1 1 1 Plexin repeat IFRD PF05004.13 OWF41558.1 - 1.5e-92 310.0 5.0 1.8e-92 309.7 5.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 OWF41558.1 - 4.4e-19 68.8 2.5 2.4e-17 63.2 0.0 2.8 3 0 0 3 3 3 1 Interferon-related protein conserved region HEAT_EZ PF13513.6 OWF41558.1 - 0.01 16.3 3.0 0.011 16.2 0.9 2.1 2 0 0 2 2 2 0 HEAT-like repeat HEXIM PF15313.6 OWF41559.1 - 8.8e-14 51.9 2.3 8.8e-14 51.9 2.3 2.4 2 1 1 3 3 3 1 Hexamethylene bis-acetamide-inducible protein YabA PF06156.13 OWF41559.1 - 1.5 9.5 7.2 0.74 10.5 0.6 2.8 2 1 1 3 3 3 0 Initiation control protein YabA Plant_NMP1 PF06694.11 OWF41560.1 - 6.1e-15 55.1 0.9 1.7e-14 53.6 0.9 1.7 1 1 0 1 1 1 1 Plant nuclear matrix protein 1 (NMP1) Latarcin PF10279.9 OWF41560.1 - 0.0043 17.4 0.3 0.014 15.8 0.1 2.0 2 1 0 2 2 2 1 Latarcin precursor FlgN PF05130.12 OWF41560.1 - 0.032 14.7 0.5 0.14 12.7 0.5 2.0 1 1 1 2 2 2 0 FlgN protein EMP24_GP25L PF01105.24 OWF41560.1 - 0.2 11.6 2.1 2.1 8.2 0.1 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD AATF-Che1 PF13339.6 OWF41560.1 - 0.94 10.2 9.3 14 6.4 7.5 2.8 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor CLN3 PF02487.17 OWF41561.1 - 2.2e-131 438.6 23.3 2.2e-131 438.6 23.3 2.3 2 1 0 2 2 2 1 CLN3 protein MFS_1 PF07690.16 OWF41561.1 - 6.6e-07 28.6 23.9 2.2e-06 26.9 24.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MCM PF00493.23 OWF41562.1 - 5.8e-99 329.7 0.0 9.8e-99 329.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OWF41562.1 - 4.7e-37 126.6 0.1 9.2e-37 125.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OWF41562.1 - 2.4e-31 108.0 1.0 7.5e-31 106.4 1.0 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OWF41562.1 - 3.8e-19 69.2 0.9 1.7e-18 67.1 0.9 2.1 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 OWF41562.1 - 1.2e-14 54.9 21.0 1.2e-14 54.9 21.0 2.7 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 OWF41562.1 - 2e-07 30.6 0.0 5.9e-06 25.8 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OWF41562.1 - 4.8e-06 26.5 0.0 0.00029 20.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF41562.1 - 3.3e-05 23.9 0.0 9e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 OWF41562.1 - 0.00048 19.9 1.3 0.0035 17.1 0.0 2.8 3 0 0 3 3 3 1 AAA lid domain Zn-ribbon_8 PF09723.10 OWF41562.1 - 0.33 11.1 1.2 0.86 9.8 1.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain RD3 PF14473.6 OWF41563.1 - 2.6e-36 124.4 1.8 3.5e-36 123.9 1.8 1.1 1 0 0 1 1 1 1 RD3 protein DUF3966 PF13110.6 OWF41563.1 - 0.081 12.8 1.9 0.15 12.0 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) FLgD_tudor PF13861.6 OWF41564.1 - 6.3e-16 58.4 43.1 25 5.2 1.0 20.6 1 1 18 19 19 19 12 FlgD Tudor-like domain WSN PF02206.18 OWF41564.1 - 5.1e-09 35.9 105.0 0.36 10.8 0.8 19.1 1 1 29 30 30 30 29 Domain of unknown function fn3 PF00041.21 OWF41565.1 - 2.6e-57 191.1 19.9 4.7e-10 39.7 1.3 15.3 15 2 0 15 15 15 8 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF41565.1 - 3.1e-12 46.9 9.5 0.00033 21.2 1.3 7.8 7 0 0 7 7 6 2 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 OWF41565.1 - 2.9e-10 40.1 5.7 0.43 10.8 0.0 9.4 11 0 0 11 11 11 3 Fibronectin type III domain Cupredoxin_1 PF13473.6 OWF41565.1 - 4.4e-08 33.2 2.7 2.5 8.3 0.0 7.6 6 1 1 7 7 7 1 Cupredoxin-like domain CHB_HEX_C_1 PF13290.6 OWF41565.1 - 2e-06 27.7 0.0 9e-05 22.4 0.0 2.9 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 OWF41565.1 - 0.00055 20.0 0.0 0.024 14.8 0.0 2.8 2 0 0 2 2 2 1 Fn3 associated Interfer-bind PF09294.10 OWF41565.1 - 0.0012 19.1 0.8 2 8.7 0.0 5.2 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III fn3_4 PF16794.5 OWF41565.1 - 0.0082 16.1 0.2 11 6.0 0.0 5.6 4 0 0 4 4 4 1 Fibronectin-III type domain Thioredoxin_8 PF13905.6 OWF41565.1 - 0.038 14.3 0.0 0.37 11.2 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin-like Thioredoxin PF00085.20 OWF41565.1 - 0.045 13.7 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Caskin1-CID PF16600.5 OWF41565.1 - 1.8 9.2 3.7 13 6.4 0.2 2.7 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Macoilin PF09726.9 OWF41565.1 - 5.2 5.5 10.5 12 4.3 10.5 1.5 1 0 0 1 1 1 0 Macoilin family NPR2 PF06218.11 OWF41566.1 - 6.4e-86 288.8 4.6 2.6e-65 220.9 5.5 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 OWF41566.1 - 0.01 14.7 2.8 0.21 10.3 0.3 2.8 1 1 2 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 DEAD PF00270.29 OWF41567.1 - 4.6e-37 127.5 0.3 1.6e-35 122.5 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF41567.1 - 1e-23 83.8 1.8 2.4e-23 82.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 OWF41567.1 - 0.00011 21.6 10.4 0.00038 19.9 0.0 2.9 3 0 0 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 OWF41567.1 - 0.0044 17.4 0.5 0.049 14.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OWF41567.1 - 0.0055 16.4 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MSP1b PF03429.13 OWF41567.1 - 0.31 9.1 3.5 0.48 8.5 3.5 1.2 1 0 0 1 1 1 0 Major surface protein 1B Cofilin_ADF PF00241.20 OWF41568.1 - 4.2e-39 133.1 1.0 9.6e-21 73.8 0.7 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein FLYWCH PF04500.16 OWF41569.1 - 0.00026 21.0 0.3 0.00069 19.7 0.1 1.8 2 0 0 2 2 2 1 FLYWCH zinc finger domain HATPase_c_2 PF13581.6 OWF41569.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CbiN PF02553.15 OWF41569.1 - 0.64 10.0 4.5 0.8 9.7 0.1 2.6 3 0 0 3 3 3 0 Cobalt transport protein component CbiN GST_C_2 PF13410.6 OWF41570.1 - 1 9.4 2.6 8.7 6.5 0.1 2.9 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain FA_FANCE PF11510.8 OWF41570.1 - 1.4 8.2 6.9 3.2 7.1 0.7 2.6 1 1 1 3 3 3 0 Fanconi Anaemia group E protein FANCE FAM76 PF16046.5 OWF41570.1 - 6.6 6.0 6.0 6.5 6.0 2.9 1.9 1 1 1 2 2 2 0 FAM76 protein Lectin_C PF00059.21 OWF41572.1 - 1e-07 32.6 10.4 0.0082 16.9 2.4 4.3 3 2 1 4 4 4 2 Lectin C-type domain DUF1467 PF07330.12 OWF41572.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1467) Protocadherin PF08374.11 OWF41572.1 - 0.0045 17.0 0.6 0.0086 16.1 0.4 1.5 2 0 0 2 2 2 1 Protocadherin WSC PF01822.19 OWF41572.1 - 0.0052 16.9 10.8 0.016 15.4 9.9 2.3 2 0 0 2 2 2 1 WSC domain TMEM154 PF15102.6 OWF41572.1 - 0.01 15.8 0.2 0.019 14.9 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Carb_bind PF10645.9 OWF41572.1 - 0.035 14.3 10.1 0.12 12.6 4.8 3.0 2 0 0 2 2 2 0 Carbohydrate binding RIFIN PF02009.16 OWF41572.1 - 0.043 13.7 0.1 0.092 12.6 0.1 1.6 1 0 0 1 1 1 0 Rifin Xlink PF00193.17 OWF41572.1 - 0.05 14.0 2.3 1.4 9.4 0.0 3.3 2 1 1 3 3 3 0 Extracellular link domain Orf78 PF06024.12 OWF41572.1 - 0.053 13.8 0.1 0.053 13.8 0.1 1.7 2 0 0 2 2 2 0 Orf78 (ac78) NS3_envE PF02723.14 OWF41572.1 - 1.5 8.9 8.4 0.06 13.4 1.0 2.4 3 0 0 3 3 3 0 Non-structural protein NS3/Small envelope protein E HAD_2 PF13419.6 OWF41573.1 - 6e-12 46.0 0.0 6.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OWF41573.1 - 2.3e-09 37.9 0.0 2.8e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OWF41573.1 - 0.00053 20.0 0.0 0.0017 18.4 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OWF41573.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 OWF41574.1 - 5.2e-23 80.7 4.3 6.2e-23 80.4 3.2 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF41574.1 - 0.00091 19.1 0.2 0.0019 18.1 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain LRR_8 PF13855.6 OWF41575.1 - 9.6e-20 70.1 13.9 3.7e-07 29.8 1.6 3.7 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OWF41575.1 - 1.5e-13 50.7 17.8 0.00014 22.2 1.1 5.2 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) CH PF00307.31 OWF41575.1 - 9.1e-13 48.3 0.0 2.3e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 OWF41575.1 - 0.0014 18.8 0.0 0.0062 16.8 0.0 2.2 1 0 0 1 1 1 1 CDC24 Calponin LRR_1 PF00560.33 OWF41575.1 - 0.0026 18.0 13.5 17 6.5 0.4 6.5 7 1 0 7 7 7 1 Leucine Rich Repeat CAMSAP_CH PF11971.8 OWF41575.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain LRR_6 PF13516.6 OWF41575.1 - 0.044 13.8 11.0 6 7.2 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat TFIID-31kDa PF02291.15 OWF41577.1 - 3.2e-46 156.4 0.0 4.8e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 OWF41577.1 - 4.3e-05 23.8 0.1 8.5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OWF41577.1 - 0.0014 18.7 0.1 0.0025 17.9 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 OWF41577.1 - 0.0032 17.4 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Rdx PF10262.9 OWF41578.1 - 1.8e-09 37.7 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Rdx family IgGFc_binding PF17517.2 OWF41579.1 - 1.2e-40 139.7 2.0 1.5e-40 139.3 2.0 1.2 1 0 0 1 1 1 1 IgGFc binding protein DICT PF10069.9 OWF41579.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system Sugar_tr PF00083.24 OWF41580.1 - 3.1e-39 135.1 21.1 3.5e-39 134.9 20.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF41580.1 - 1.1e-31 110.0 46.5 4e-27 95.1 28.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF41581.1 - 4.2e-32 111.6 22.3 4.2e-32 111.6 22.3 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF41581.1 - 8.8e-28 97.2 61.3 1e-25 90.5 33.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MMS22L_N PF14910.6 OWF41582.1 - 4.1e-108 362.7 17.1 8.3e-108 361.7 17.1 1.5 1 1 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal MMS22L_C PF14911.6 OWF41582.1 - 1.1e-62 212.3 1.7 2e-62 211.4 1.7 1.5 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal MFS_1 PF07690.16 OWF41584.1 - 4e-12 45.7 40.6 2e-08 33.5 12.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2964 PF11177.8 OWF41584.1 - 9.3 6.5 7.3 0.5 10.6 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) MFS_1 PF07690.16 OWF41585.1 - 9.8e-09 34.6 19.1 9.8e-09 34.6 19.1 2.2 2 1 1 3 3 3 2 Major Facilitator Superfamily NAD_binding_8 PF13450.6 OWF41586.1 - 7.7e-14 51.7 3.6 3.8e-13 49.4 1.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OWF41586.1 - 2.1e-11 43.8 0.1 6e-10 39.0 0.1 2.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OWF41586.1 - 4.7e-07 29.3 0.4 0.00031 19.9 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OWF41586.1 - 0.0017 18.0 0.4 0.022 14.4 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF41586.1 - 0.002 17.4 0.2 0.0039 16.5 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 OWF41586.1 - 0.005 15.4 0.1 1.3 7.4 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_oxidored PF12831.7 OWF41586.1 - 0.0056 16.1 0.7 0.084 12.2 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF41586.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 OWF41586.1 - 0.02 14.2 1.0 0.037 13.3 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OWF41586.1 - 0.021 14.1 0.5 0.084 12.1 0.2 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF41586.1 - 0.028 15.0 0.5 0.11 13.0 0.5 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OWF41586.1 - 0.29 11.0 0.7 1.1 9.2 0.3 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1664 PF07889.12 OWF41587.1 - 0.0034 17.4 1.0 0.0054 16.8 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 OWF41587.1 - 0.033 14.1 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF16 PF01519.16 OWF41587.1 - 0.038 14.5 0.5 0.077 13.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 ARGLU PF15346.6 OWF41587.1 - 0.056 13.3 4.0 0.081 12.8 4.0 1.4 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 NAD_binding_8 PF13450.6 OWF41588.1 - 2.3e-14 53.4 1.0 5.6e-14 52.1 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OWF41588.1 - 4.2e-11 42.8 0.0 1.8e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OWF41588.1 - 1.5e-05 24.2 1.8 0.00025 20.2 0.6 2.5 2 1 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 OWF41588.1 - 0.0004 19.8 0.1 0.00082 18.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OWF41588.1 - 0.00099 18.8 0.6 0.00099 18.8 0.6 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF41588.1 - 0.0016 17.7 0.1 0.022 14.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF41588.1 - 0.026 13.9 0.7 0.026 13.9 0.7 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OWF41588.1 - 0.028 13.7 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 OWF41588.1 - 0.029 13.2 0.3 0.041 12.7 0.3 1.1 1 0 0 1 1 1 0 MCRA family FAD_binding_3 PF01494.19 OWF41588.1 - 0.069 12.4 0.9 0.12 11.6 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OWF41588.1 - 0.17 10.6 0.7 0.3 9.8 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OWF41588.1 - 0.17 10.9 0.8 0.3 10.1 0.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Duffy_binding PF05424.11 OWF41588.1 - 0.17 11.9 0.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Duffy binding domain F-box-like PF12937.7 OWF41589.1 - 1.4e-12 47.2 2.9 3.1e-12 46.2 2.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF41589.1 - 3.2e-11 42.8 2.5 7.7e-11 41.6 2.5 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 OWF41589.1 - 2.7e-10 40.6 3.4 0.0036 18.1 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat F-box_4 PF15966.5 OWF41589.1 - 0.027 14.3 0.4 0.1 12.5 0.4 1.9 1 0 0 1 1 1 0 F-box tRNA_NucTran2_2 PF13735.6 OWF41589.1 - 0.081 12.9 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative W_rich_C PF07483.11 OWF41589.1 - 0.97 9.6 5.8 0.54 10.4 0.6 2.9 2 1 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain HU-CCDC81_bac_2 PF18175.1 OWF41590.1 - 8.2 6.4 13.1 48 3.9 0.7 5.3 4 0 0 4 4 4 0 CCDC81-like prokaryotic HU domain 2 Pex2_Pex12 PF04757.14 OWF41591.1 - 3.7e-40 137.9 0.1 4.5e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 OWF41591.1 - 0.0018 18.5 4.3 0.0035 17.6 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OWF41591.1 - 0.0032 17.3 4.2 0.0062 16.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF41591.1 - 0.0033 17.2 3.9 0.0065 16.3 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF41591.1 - 0.0041 16.9 3.4 0.0069 16.2 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41591.1 - 1.1 9.4 6.6 2.3 8.3 6.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Adaptin_N PF01602.20 OWF41592.1 - 8.5e-157 522.9 15.9 1.1e-156 522.5 15.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OWF41592.1 - 2.8e-65 219.3 13.8 3.2e-63 212.6 2.2 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 OWF41592.1 - 2.4e-29 101.7 1.6 5.6e-29 100.5 0.7 2.2 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 OWF41592.1 - 5.9e-18 65.0 6.9 1.6e-06 28.4 0.1 5.9 3 3 5 8 8 8 6 HEAT repeats HEAT PF02985.22 OWF41592.1 - 5.6e-12 44.8 9.4 0.014 15.6 0.1 6.7 7 0 0 7 7 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 OWF41592.1 - 3e-09 37.2 0.9 3e-09 37.2 0.9 2.6 4 0 0 4 4 2 1 Adaptin C-terminal domain Cnd3 PF12719.7 OWF41592.1 - 1.7e-08 34.1 3.4 9.3e-06 25.0 0.3 3.0 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OWF41592.1 - 2.8e-06 27.2 4.9 0.31 11.1 0.0 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OWF41592.1 - 1e-05 25.3 3.0 0.16 11.5 0.1 3.8 2 2 1 3 3 3 3 CLASP N terminal UNC45-central PF11701.8 OWF41592.1 - 0.00011 22.2 0.4 0.0047 16.9 0.1 3.1 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 OWF41592.1 - 0.00016 22.1 5.0 4.3 7.9 0.0 6.0 6 1 2 8 8 7 1 HEAT-like repeat RTP1_C1 PF10363.9 OWF41592.1 - 0.00088 19.4 6.7 0.69 10.1 0.0 5.2 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 OWF41592.1 - 0.0028 17.6 3.6 0.0078 16.1 0.2 3.3 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Atx10homo_assoc PF09759.9 OWF41592.1 - 0.0034 17.4 5.2 0.69 10.0 0.1 4.9 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 OWF41592.1 - 0.023 14.1 1.9 0.026 14.0 0.1 2.0 2 0 0 2 2 2 0 Armadillo-like AP3B1_C PF14796.6 OWF41592.1 - 0.089 13.1 1.8 0.27 11.5 0.0 2.5 3 0 0 3 3 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal RasGEF_N_2 PF14663.6 OWF41592.1 - 0.14 12.5 3.2 4.1 7.8 0.1 4.1 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Alpha_adaptin_C PF02296.16 OWF41592.1 - 0.2 11.9 0.9 0.82 9.9 0.3 2.5 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain Mo25 PF08569.11 OWF41592.1 - 0.24 10.7 5.8 0.13 11.6 0.3 2.4 2 1 0 2 2 2 0 Mo25-like Piwi PF02171.17 OWF41593.1 - 2e-94 316.2 0.2 2.9e-94 315.7 0.2 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 OWF41593.1 - 1.1e-32 112.7 0.0 2.3e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 OWF41593.1 - 7.8e-05 23.3 0.0 0.00018 22.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute adh_short PF00106.25 OWF41595.1 - 5.3e-30 104.3 0.0 7.6e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF41595.1 - 2.1e-17 63.5 0.0 2.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF41595.1 - 4.1e-07 30.1 0.0 5.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF41595.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TRAM_LAG1_CLN8 PF03798.16 OWF41596.1 - 2.5e-15 56.7 25.4 2.5e-15 56.7 25.4 1.4 2 0 0 2 2 2 1 TLC domain Neur_chan_LBD PF02931.23 OWF41597.1 - 1.3e-39 135.9 0.4 1.9e-39 135.4 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41597.1 - 3.5e-18 66.5 11.0 9.8e-17 61.8 5.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2231 PF09990.9 OWF41597.1 - 1.3 9.5 3.5 0.71 10.3 0.1 2.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) Neur_chan_LBD PF02931.23 OWF41598.1 - 6.2e-34 117.3 2.0 1.1e-33 116.6 2.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41598.1 - 5.3e-21 75.8 9.6 1.4e-20 74.4 9.6 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PAF PF15715.5 OWF41598.1 - 0.085 13.5 0.2 0.13 12.9 0.2 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain CathepsinC_exc PF08773.11 OWF41598.1 - 0.091 13.0 0.7 0.7 10.2 0.3 2.4 2 0 0 2 2 2 0 Cathepsin C exclusion domain T-box PF00907.22 OWF41599.1 - 1.2e-81 273.4 0.2 1.7e-81 272.9 0.2 1.2 1 0 0 1 1 1 1 T-box dCache_1 PF02743.18 OWF41600.1 - 5.4e-21 75.5 1.3 5.2e-11 42.8 0.0 3.2 3 0 0 3 3 3 2 Cache domain VWA_N PF08399.11 OWF41600.1 - 6e-12 46.1 0.9 7.3e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 VWA N-terminal VWA_2 PF13519.6 OWF41600.1 - 9.9e-12 45.5 0.0 2.9e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF41600.1 - 1.9e-10 41.2 0.2 4e-10 40.2 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF41600.1 - 4e-10 39.8 0.0 7.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Mid2 PF04478.12 OWF41600.1 - 0.0034 17.2 0.1 0.0076 16.1 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Protocadherin PF08374.11 OWF41600.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 OWF41600.1 - 0.038 13.9 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4690 PF15756.5 OWF41600.1 - 0.065 13.8 0.8 0.3 11.7 0.8 2.1 1 0 0 1 1 1 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 OWF41600.1 - 0.11 13.4 0.0 0.36 11.7 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OWF41600.1 - 1.4 8.4 6.4 3.6 7.1 6.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RGS PF00615.19 OWF41601.1 - 0.024 14.9 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain RGS PF00615.19 OWF41602.1 - 3.9e-24 85.2 3.9 7.2e-12 45.6 0.3 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF4490 PF14892.6 OWF41604.1 - 1.7e-33 114.8 0.5 1.9e-33 114.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Tmemb_40 PF10160.9 OWF41606.1 - 1.7e-67 227.5 11.0 2e-67 227.3 11.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein DRMBL PF07522.14 OWF41607.1 - 6e-12 45.7 0.0 2.9e-11 43.5 0.0 2.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OWF41607.1 - 0.00014 21.5 0.2 0.00038 20.0 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain WD40 PF00400.32 OWF41608.1 - 8e-44 146.8 36.8 3.3e-07 30.9 0.6 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 OWF41608.1 - 4.7e-11 42.4 1.0 1e-10 41.3 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF41608.1 - 8.7e-08 31.9 0.6 2.4e-07 30.5 0.6 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OWF41608.1 - 1.5e-06 27.2 18.2 0.47 9.0 0.2 5.9 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box_4 PF15966.5 OWF41608.1 - 1.6e-05 24.7 0.4 9.6e-05 22.2 0.4 2.4 1 0 0 1 1 1 1 F-box ANAPC4_WD40 PF12894.7 OWF41608.1 - 3.1e-05 24.2 4.3 0.85 10.0 0.1 4.6 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF41608.1 - 0.008 15.5 0.1 0.018 14.4 0.1 1.7 1 1 0 1 1 1 1 WD40-like domain YfkB PF08756.10 OWF41608.1 - 0.14 12.0 1.4 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 YfkB-like domain LAMTOR5 PF16672.5 OWF41609.1 - 8.6e-26 89.7 0.1 9.5e-26 89.6 0.1 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 OWF41609.1 - 0.00014 21.6 0.1 0.0004 20.1 0.1 1.8 1 1 0 1 1 1 1 Roadblock/LC7 domain GRDP-like PF07173.12 OWF41610.1 - 2.7e-47 161.0 2.0 5.8e-36 124.3 0.2 3.0 1 1 2 3 3 3 3 Glycine-rich domain-containing protein-like DUF4084 PF13321.6 OWF41610.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) A_deaminase PF00962.22 OWF41612.1 - 7.5e-43 147.1 0.0 9.3e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase CdiI_4 PF18624.1 OWF41612.1 - 0.016 15.6 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 CDI immunity protein DUF3994 PF13159.6 OWF41613.1 - 0.15 12.6 10.5 4.6 7.9 0.1 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF3994) DASH_Dam1 PF08653.10 OWF41613.1 - 0.25 11.2 14.3 48 3.9 0.1 6.9 5 2 3 8 8 8 0 DASH complex subunit Dam1 DUF3972 PF13118.6 OWF41613.1 - 2.9 8.4 26.1 7.4 7.0 1.2 4.8 1 1 3 5 5 5 0 Protein of unknown function (DUF3972) SPATA1_C PF15743.5 OWF41613.1 - 6.5 6.8 6.4 77 3.3 0.2 3.5 2 1 0 3 3 3 0 Spermatogenesis-associated C-terminus DUF1735 PF08522.10 OWF41615.1 - 0.13 12.9 9.9 1.6e+03 -0.3 9.9 3.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1735) Glyco_hyd_101C PF17451.2 OWF41615.1 - 0.13 12.5 9.8 9.9e+02 0.0 9.8 3.4 1 1 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain RL10P_insert PF17777.1 OWF41615.1 - 0.86 9.6 40.0 12 6.0 3.1 6.7 1 1 6 7 7 7 0 Insertion domain in 60S ribosomal protein L10P Neur_chan_LBD PF02931.23 OWF41616.1 - 7.2e-71 238.1 0.6 9.8e-71 237.6 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41616.1 - 2.5e-56 191.4 0.1 3.3e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2678 PF10856.8 OWF41616.1 - 0.0037 17.2 0.4 0.011 15.7 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) MSC PF09402.10 OWF41616.1 - 0.067 12.6 0.5 0.51 9.7 0.0 2.0 1 1 0 2 2 2 0 Man1-Src1p-C-terminal domain Na_Ca_ex_C PF16494.5 OWF41616.1 - 0.55 10.7 2.0 2.6 8.5 0.8 2.2 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain RDD PF06271.12 OWF41616.1 - 5.1 7.3 8.1 2.4 8.3 0.3 2.6 2 1 0 2 2 2 0 RDD family Neur_chan_memb PF02932.16 OWF41617.1 - 5.8e-65 219.7 0.2 7.4e-65 219.3 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF41617.1 - 8.7e-65 218.2 3.9 1.2e-64 217.8 3.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.9 OWF41617.1 - 2.2 7.6 7.7 4.5 6.6 7.7 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Neur_chan_memb PF02932.16 OWF41618.1 - 2.4e-84 283.2 3.4 4e-84 282.4 3.4 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF41618.1 - 4.1e-78 261.7 1.1 5.4e-78 261.4 1.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1765 PF08578.10 OWF41618.1 - 0.023 15.2 0.8 0.073 13.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) DUF417 PF04224.12 OWF41618.1 - 0.52 9.8 4.3 1.1 8.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF417 Prion_bPrPp PF11587.8 OWF41618.1 - 1.9 8.4 6.2 0.16 11.9 0.6 2.1 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal Neur_chan_memb PF02932.16 OWF41619.1 - 3.2e-74 250.0 1.2 4.5e-74 249.5 1.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF41619.1 - 1.4e-67 227.3 0.3 1.9e-67 226.9 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PA_decarbox PF05870.11 OWF41619.1 - 0.09 12.4 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) DUF2417 PF10329.9 OWF41619.1 - 1 8.7 6.7 7.5 5.9 6.9 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) CTC1 PF15489.6 OWF41620.1 - 7.7e-43 146.3 8.0 5.7e-38 130.2 3.0 3.1 2 1 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 CTC1 PF15489.6 OWF41621.1 - 6.7e-11 40.5 0.2 9.9e-11 39.9 0.2 1.1 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 DUF1180 PF06679.12 OWF41622.1 - 2.3e-23 83.4 3.3 6e-23 82.1 3.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 OWF41622.1 - 0.007 17.2 0.0 1.7 9.5 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF2681 PF10883.8 OWF41622.1 - 0.0074 16.7 0.1 0.055 13.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) Mucin PF01456.17 OWF41622.1 - 0.015 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Conotoxin PF02950.17 OWF41622.1 - 0.025 15.6 0.1 0.051 14.6 0.1 1.5 1 0 0 1 1 1 0 Conotoxin TRAP_alpha PF03896.16 OWF41622.1 - 0.27 10.4 2.7 1.6 7.9 0.8 2.0 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TMEM154 PF15102.6 OWF41622.1 - 0.41 10.6 3.8 7.6 6.4 0.2 2.3 1 1 1 2 2 2 0 TMEM154 protein family TMEM132D_C PF15706.5 OWF41622.1 - 0.48 10.2 2.8 0.39 10.5 0.2 2.0 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Orf78 PF06024.12 OWF41622.1 - 2.7 8.3 7.6 0.86 9.9 0.1 2.3 1 1 1 2 2 2 0 Orf78 (ac78) Ribosomal_L4 PF00573.22 OWF41623.1 - 1.2e-40 139.3 0.0 1.2e-40 139.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OWF41623.1 - 8e-08 32.2 1.2 8e-08 32.2 1.2 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF3913 PF13052.6 OWF41623.1 - 0.095 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) GCP_N_terminal PF17681.1 OWF41624.1 - 7.6e-62 209.7 1.1 2.1e-61 208.2 0.1 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OWF41624.1 - 8.3e-59 199.6 12.3 8.3e-59 199.6 12.3 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal MIB_HERC2 PF06701.13 OWF41625.1 - 1.8e-22 79.3 23.2 9e-12 45.1 4.6 3.5 3 0 0 3 3 3 2 Mib_herc2 VWA_2 PF13519.6 OWF41625.1 - 1.7e-15 57.6 0.0 8.7e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OWF41625.1 - 1.1e-13 51.9 0.0 2.7e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain WWE PF02825.20 OWF41625.1 - 6.7e-07 29.8 0.3 6.7e-07 29.8 0.3 2.3 2 0 0 2 2 2 1 WWE domain VWA_3 PF13768.6 OWF41625.1 - 0.0039 17.2 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain SH3_15 PF18346.1 OWF41625.1 - 0.05 13.9 2.0 1.8 8.9 0.1 2.7 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain MIB_HERC2 PF06701.13 OWF41626.1 - 1.6e-26 92.3 17.7 1.1e-14 54.4 1.2 3.3 4 0 0 4 4 3 2 Mib_herc2 Roc PF08477.13 OWF41626.1 - 3e-17 63.0 0.3 5.2e-09 36.3 0.1 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF41626.1 - 1e-16 61.4 1.8 2.2e-16 60.3 1.8 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain VWA PF00092.28 OWF41626.1 - 4.8e-14 53.0 0.0 1e-13 51.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF41626.1 - 1.3e-11 45.0 0.0 3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ras PF00071.22 OWF41626.1 - 4.4e-09 36.1 0.1 0.001 18.7 0.0 2.5 2 0 0 2 2 2 2 Ras family WWE PF02825.20 OWF41626.1 - 7.6e-08 32.8 0.0 3e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 WWE domain AAA_18 PF13238.6 OWF41626.1 - 0.011 16.3 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF41626.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain K-box PF01486.17 OWF41626.1 - 0.02 15.1 1.1 0.099 12.8 0.2 2.6 3 0 0 3 3 2 0 K-box region RNA_helicase PF00910.22 OWF41626.1 - 0.029 14.8 0.0 0.085 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OWF41626.1 - 0.035 14.3 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OWF41626.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Septin PF00735.18 OWF41626.1 - 0.05 12.9 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OWF41626.1 - 0.078 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OWF41626.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OWF41626.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 OWF41626.1 - 0.1 12.3 0.0 0.33 10.7 0.0 1.9 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OWF41626.1 - 0.12 11.7 0.2 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Arf PF00025.21 OWF41626.1 - 0.16 11.4 0.7 7.6 6.0 0.0 2.9 4 0 0 4 4 3 0 ADP-ribosylation factor family AAA PF00004.29 OWF41626.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 OWF41627.1 - 3.5e-36 124.9 28.6 2.6e-28 99.0 4.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF41627.1 - 8.6e-13 47.9 4.0 8.6e-13 47.9 4.0 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OWF41627.1 - 6.2e-06 24.9 0.9 1.1e-05 24.1 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LRR_4 PF12799.7 OWF41629.1 - 0.04 14.4 0.1 0.78 10.3 0.1 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) TSC21 PF15217.6 OWF41630.1 - 0.019 14.9 0.1 8.7 6.3 0.1 2.3 2 0 0 2 2 2 0 TSC21 family RepB-RCR_reg PF10723.9 OWF41632.1 - 0.033 14.1 0.6 8.9 6.3 0.0 3.5 1 1 3 4 4 4 0 Replication regulatory protein RepB IFT57 PF10498.9 OWF41632.1 - 0.4 9.6 6.9 0.45 9.4 1.3 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 PEARLI-4 PF05278.12 OWF41632.1 - 3.5 7.2 7.7 6.6 6.2 7.7 1.6 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) RepB-RCR_reg PF10723.9 OWF41633.1 - 0.21 11.6 0.7 1.1e+02 2.8 0.0 3.9 1 1 3 4 4 4 0 Replication regulatory protein RepB Calpain_u2 PF16648.5 OWF41633.1 - 4.1 7.9 8.5 17 5.9 0.4 3.5 1 1 2 3 3 3 0 Unstructured region on Calpain-3 Pterin_bind PF00809.22 OWF41633.1 - 7.3 6.2 13.9 8.2 6.0 1.7 3.5 1 1 3 4 4 4 0 Pterin binding enzyme IFT57 PF10498.9 OWF41633.1 - 7.6 5.4 10.2 9 5.2 1.3 3.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 zf_C2H2_ZHX PF18387.1 OWF41634.1 - 0.038 13.6 0.3 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain THAP PF05485.12 OWF41636.1 - 5.3e-07 30.5 1.6 8.9e-07 29.8 1.6 1.6 1 1 0 1 1 1 1 THAP domain Peptidase_S64 PF08192.11 OWF41639.1 - 0.041 12.4 0.0 0.1 11.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_S64 PF08192.11 OWF41640.1 - 0.048 12.2 0.0 0.099 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S64 IgGFc_binding PF17517.2 OWF41641.1 - 6.6e-48 163.5 9.0 1.7e-47 162.2 6.5 2.1 2 0 0 2 2 2 2 IgGFc binding protein TatD_DNase PF01026.21 OWF41642.1 - 1.8e-06 27.6 0.0 3.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 TatD related DNase LEF-9 PF05094.12 OWF41642.1 - 0.19 10.2 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) IgGFc_binding PF17517.2 OWF41644.1 - 6e-45 153.8 12.5 6e-45 153.8 12.5 2.1 2 0 0 2 2 2 2 IgGFc binding protein DUF4871 PF16167.5 OWF41644.1 - 0.075 13.1 0.5 0.22 11.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) Cornifin PF02389.15 OWF41645.1 - 5.9e-09 36.2 7.3 7.6e-09 35.9 7.3 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family Mid2 PF04478.12 OWF41646.1 - 0.03 14.2 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor IgGFc_binding PF17517.2 OWF41647.1 - 4.1e-50 170.7 9.7 4.1e-50 170.7 9.7 2.0 2 0 0 2 2 2 1 IgGFc binding protein PEN-2 PF10251.9 OWF41648.1 - 4e-41 139.4 2.8 4.4e-41 139.2 2.8 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase zf-CCCH PF00642.24 OWF41649.1 - 1.6e-13 50.2 16.5 1.5e-06 27.9 6.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OWF41649.1 - 6.2e-07 30.1 2.0 0.019 15.6 0.2 2.6 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 OWF41649.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OWF41649.1 - 7e-05 22.7 14.0 0.029 14.4 2.6 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OWF41649.1 - 0.014 15.6 2.4 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family CFAP91 PF14738.6 OWF41651.1 - 2.4e-67 225.8 11.2 2.4e-67 225.8 11.2 3.4 2 1 1 3 3 3 1 Cilia- and flagella-associated protein 91 Phage_TAC_5 PF08890.11 OWF41651.1 - 0.011 15.7 5.3 0.035 14.1 5.3 1.9 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC DUF5624 PF18538.1 OWF41651.1 - 0.011 15.8 0.5 0.038 14.1 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Hemolysin_N PF12563.8 OWF41651.1 - 0.011 15.3 1.0 0.033 13.8 0.1 2.2 2 0 0 2 2 2 0 Hemolytic toxin N terminal CelTOS PF18659.1 OWF41651.1 - 0.04 14.3 0.4 0.12 12.8 0.4 1.8 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Pterin_bind PF00809.22 OWF41651.1 - 0.075 12.7 1.4 0.23 11.1 1.4 1.8 1 1 0 1 1 1 0 Pterin binding enzyme Linker_histone PF00538.19 OWF41652.1 - 2.6e-24 85.4 3.1 2.6e-24 85.4 3.1 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family BBL5 PF07289.11 OWF41652.1 - 0.31 10.0 1.0 0.41 9.6 1.0 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein RR_TM4-6 PF06459.12 OWF41652.1 - 2.8 7.7 12.4 3.4 7.4 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Linker_histone PF00538.19 OWF41653.1 - 1.2e-25 89.6 1.9 1.2e-25 89.6 1.9 2.4 3 1 0 3 3 3 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 OWF41653.1 - 8.7 6.1 11.7 9.9 5.9 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Linker_histone PF00538.19 OWF41654.1 - 2.5e-24 85.4 2.5 2.5e-24 85.4 2.5 2.4 2 0 0 2 2 2 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 OWF41654.1 - 8.1 6.2 11.8 9.5 6.0 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gly_transf_sug PF04488.15 OWF41655.1 - 2.1e-06 28.3 0.0 4.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OWF41655.1 - 7.1e-06 25.6 0.1 9.8e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 OWF41655.1 - 0.73 9.1 3.0 1.2 8.3 0.0 2.4 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain DUF3060 PF11259.8 OWF41656.1 - 1.7e-33 114.1 42.8 9.6 6.0 0.0 25.5 1 1 15 28 28 28 28 Protein of unknown function (DUF3060) DUF3060 PF11259.8 OWF41657.1 - 2.9e-07 30.1 18.5 7.7 6.3 0.0 8.8 3 2 7 11 11 11 8 Protein of unknown function (DUF3060) DUF1641 PF07849.11 OWF41657.1 - 1.1 9.2 9.7 15 5.5 0.2 5.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1641) Pkinase PF00069.25 OWF41658.1 - 1.3e-75 254.2 1.7 1.8e-75 253.7 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41658.1 - 3.7e-43 147.7 0.0 7.3e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF41658.1 - 8.4e-07 28.6 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 OWF41658.1 - 1e-05 25.2 0.0 3.5e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 OWF41658.1 - 0.0089 15.0 3.9 0.019 13.9 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OWF41658.1 - 0.013 14.8 0.3 0.013 14.8 0.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2347 PF09804.9 OWF41658.1 - 0.78 9.3 2.7 1.8 8.1 2.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) CBP_BcsR PF10945.8 OWF41659.1 - 3.9e-07 29.4 0.0 66 3.1 0.0 10.8 3 1 21 26 26 26 1 Cellulose biosynthesis protein BcsR CBP_BcsR PF10945.8 OWF41660.1 - 3.4e-06 26.4 0.0 4.4 6.9 0.0 4.5 4 2 1 5 5 5 4 Cellulose biosynthesis protein BcsR Lectin_like PF18560.1 OWF41660.1 - 0.081 13.1 1.7 0.44 10.7 0.2 2.0 1 1 1 2 2 2 0 Lectin like domain NEXCaM_BD PF16644.5 OWF41660.1 - 0.093 13.0 0.2 13 6.1 0.1 2.9 1 1 2 3 3 3 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Colicin_K PF17500.2 OWF41660.1 - 0.19 12.3 16.0 9.5 6.9 0.2 4.1 1 1 4 5 5 5 0 Colicin-K Tox-WTIP PF15654.6 OWF41660.1 - 0.23 11.9 5.7 6 7.3 0.5 2.6 1 1 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif 2OG-FeII_Oxy_5 PF13759.6 OWF41660.1 - 2.8 8.4 13.9 30 5.1 1.3 6.0 1 1 2 3 3 3 0 Putative 2OG-Fe(II) oxygenase MatE PF01554.18 OWF41661.1 - 7.3e-60 201.3 43.4 1.3e-31 109.5 15.8 2.9 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OWF41661.1 - 3.5e-05 23.9 14.8 3.5e-05 23.9 14.8 5.2 3 1 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain PseudoU_synth_2 PF00849.22 OWF41662.1 - 1.8e-23 83.4 0.0 4.3e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase Stevor PF17410.2 OWF41662.1 - 0.49 9.9 2.8 17 4.9 0.0 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame ThiS-like PF14453.6 OWF41662.1 - 5.6 7.1 6.7 0.95 9.6 0.4 2.8 3 0 0 3 3 3 0 ThiS-like ubiquitin Sulfotransfer_2 PF03567.14 OWF41663.1 - 2.8e-20 73.3 1.5 8.6e-17 61.9 0.1 2.1 1 1 0 2 2 2 2 Sulfotransferase family Ribosomal_L27e PF01777.18 OWF41663.1 - 0.00062 20.1 0.2 1.4 9.3 0.2 3.1 3 0 0 3 3 3 2 Ribosomal L27e protein family PKD_3 PF16820.5 OWF41663.1 - 0.089 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 PKD-like domain GHL10 PF02638.15 OWF41664.1 - 8.3e-77 258.3 0.5 1.1e-76 257.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_hydro_66 PF13199.6 OWF41664.1 - 0.0012 17.6 0.5 0.0026 16.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 66 GHL6 PF14871.6 OWF41664.1 - 0.14 12.3 0.0 0.53 10.4 0.0 2.0 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Patched PF02460.18 OWF41665.1 - 1.9e-126 423.2 19.4 2.6e-126 422.8 19.4 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF41665.1 - 1.2e-34 119.4 7.2 1.2e-34 119.4 7.2 3.2 2 1 1 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Mor PF08765.11 OWF41665.1 - 0.17 11.9 0.1 2.5 8.1 0.0 2.5 3 0 0 3 3 3 0 Mor transcription activator family ketoacyl-synt PF00109.26 OWF41666.1 - 1.2e-79 267.4 0.0 2.4e-79 266.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OWF41666.1 - 2.4e-52 177.5 0.0 4.8e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 OWF41666.1 - 1.5e-49 169.2 0.0 2.9e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OWF41666.1 - 5.1e-38 129.7 0.1 1.2e-37 128.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 OWF41666.1 - 1.4e-30 106.5 0.0 2.5e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.20 OWF41666.1 - 2.1e-23 82.7 0.3 5.6e-23 81.3 0.3 1.7 1 0 0 1 1 1 1 Condensation domain KAsynt_C_assoc PF16197.5 OWF41666.1 - 7.7e-17 61.8 0.0 2e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 OWF41666.1 - 8.2e-08 32.5 0.1 3.5e-07 30.5 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OWF41666.1 - 9e-06 25.3 0.2 5e-05 22.9 0.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 OWF41666.1 - 9.3e-05 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glyco_hydro_72 PF03198.14 OWF41666.1 - 0.0055 16.0 0.1 1.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Glucanosyltransferase Patched PF02460.18 OWF41667.1 - 1.3e-144 483.3 26.7 1.6e-144 483.0 26.7 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF41667.1 - 1.1e-36 126.0 4.3 1.1e-36 126.0 4.3 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation VirDNA-topo-I_N PF09266.10 OWF41667.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal ACR_tran PF00873.19 OWF41667.1 - 1.7 6.2 13.9 2.6 5.6 13.9 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Rieske_2 PF13806.6 OWF41668.1 - 2.4e-11 43.5 0.0 3.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 OWF41668.1 - 1.1e-10 41.3 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LMWPc PF01451.21 OWF41669.1 - 1.7e-35 122.5 0.0 1.9e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Vinculin PF01044.19 OWF41671.1 - 0 1187.5 24.8 0 1187.2 24.8 1.0 1 0 0 1 1 1 1 Vinculin family COG2 PF06148.11 OWF41671.1 - 0.091 12.9 11.4 3.7 7.6 0.0 5.6 7 0 0 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 ArnB_C PF18677.1 OWF41671.1 - 0.26 11.4 3.6 0.44 10.7 0.8 3.0 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain I_LWEQ PF01608.17 OWF41671.1 - 4.5 7.5 40.2 0.039 14.2 6.1 6.5 5 2 3 8 8 8 0 I/LWEQ domain Forkhead PF00250.18 OWF41672.1 - 1.4e-33 115.0 0.0 2.9e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain HrcA_DNA-bdg PF03444.15 OWF41672.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Phospho_p8 PF10195.9 OWF41673.1 - 2.4e-18 66.4 8.8 3e-18 66.0 8.8 1.1 1 0 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 Phospho_p8 PF10195.9 OWF41674.1 - 2.2e-20 72.9 2.6 2.7e-20 72.6 2.6 1.2 1 0 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 M20_dimer PF07687.14 OWF41674.1 - 0.077 12.9 0.4 0.18 11.8 0.4 1.6 1 1 0 1 1 1 0 Peptidase dimerisation domain Prenylcys_lyase PF07156.14 OWF41675.1 - 4.9e-118 394.4 1.4 6e-118 394.1 1.4 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 OWF41675.1 - 1.7e-08 34.6 0.1 3.7e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OWF41675.1 - 0.00014 21.3 0.0 0.0012 18.2 0.0 2.2 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OWF41675.1 - 0.00063 19.1 0.3 0.012 14.9 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF41675.1 - 0.0045 16.6 0.3 0.0074 15.9 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Smac_DIABLO PF09057.10 OWF41676.1 - 6.1e-22 78.1 9.3 1.2e-21 77.2 9.3 1.4 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases Peptidase_S49_N PF08496.10 OWF41676.1 - 0.00094 19.3 5.7 0.0022 18.1 5.7 1.6 1 0 0 1 1 1 1 Peptidase family S49 N-terminal PA26 PF04636.13 OWF41676.1 - 0.19 10.6 6.8 0.28 10.0 6.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PBP_sp32 PF07222.12 OWF41676.1 - 0.36 10.2 9.6 0.63 9.5 9.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Conotoxin PF02950.17 OWF41676.1 - 2.4 9.2 6.4 16 6.6 0.1 3.1 2 0 0 2 2 2 0 Conotoxin Connexin PF00029.19 OWF41676.1 - 4.7 6.9 5.9 11 5.7 5.9 1.7 1 0 0 1 1 1 0 Connexin ETX_MTX2 PF03318.13 OWF41677.1 - 2.7e-06 27.3 6.4 3.3e-06 27.0 6.4 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 p450 PF00067.22 OWF41678.1 - 2.7e-48 164.9 0.6 3.5e-48 164.5 0.6 1.1 1 0 0 1 1 1 1 Cytochrome P450 Neur_chan_LBD PF02931.23 OWF41679.1 - 2.4e-36 125.2 0.0 3.4e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41679.1 - 3.5e-17 63.3 17.0 2.8e-15 57.0 11.1 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF41680.1 - 6.5e-41 140.1 0.8 9.1e-41 139.7 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41680.1 - 2.5e-18 67.0 15.5 2.1e-16 60.7 10.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region BRI3BP PF14965.6 OWF41680.1 - 0.056 13.0 3.1 0.11 12.0 3.1 1.5 1 0 0 1 1 1 0 Negative regulator of p53/TP53 PIG-P PF08510.12 OWF41680.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 PIG-P Neur_chan_LBD PF02931.23 OWF41681.1 - 1.6e-42 145.4 5.2 2.3e-42 144.9 5.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41681.1 - 1e-26 94.5 0.0 1.5e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ssu72 PF04722.13 OWF41681.1 - 0.0043 16.6 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Ssu72-like protein DUF3377 PF11857.8 OWF41681.1 - 0.045 13.7 2.7 6.7 6.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) PCI PF01399.27 OWF41682.1 - 1.4e-12 48.1 4.3 3.9e-12 46.6 4.3 1.8 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 OWF41682.1 - 6.2e-09 35.4 3.7 1.3e-08 34.4 3.7 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DUF5106 PF17127.4 OWF41682.1 - 0.053 13.8 2.5 2.1 8.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5106) Methyltransf_31 PF13847.6 OWF41683.1 - 4.9e-23 81.6 0.0 6.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF41683.1 - 5.7e-17 62.2 0.0 9.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF41683.1 - 8.6e-16 58.4 0.0 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF41683.1 - 1.6e-13 51.2 0.0 2.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF41683.1 - 5.6e-13 49.1 0.0 6.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF41683.1 - 3.2e-07 29.9 0.0 5.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OWF41683.1 - 8.2e-07 28.5 0.1 1.1e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OWF41683.1 - 1.2e-06 28.2 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OWF41683.1 - 9.4e-06 25.4 0.0 1.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 OWF41683.1 - 0.00046 19.7 0.0 0.00061 19.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 OWF41683.1 - 0.00069 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 OWF41683.1 - 0.0008 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OWF41683.1 - 0.0021 17.5 0.0 0.0043 16.5 0.0 1.4 2 0 0 2 2 2 1 Putative methyltransferase DREV PF05219.12 OWF41683.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_24 PF13578.6 OWF41683.1 - 0.027 15.5 0.0 0.042 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 OWF41683.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW tRNA-synt_1e PF01406.19 OWF41686.1 - 9.5e-106 353.5 7.5 9.5e-106 353.5 7.5 1.9 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OWF41686.1 - 0.0023 16.7 0.1 0.0023 16.7 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (M) DNTTIP1_dimer PF18192.1 OWF41686.1 - 0.0085 16.4 2.7 2.5 8.5 1.4 2.8 2 0 0 2 2 2 2 DNTTIP1 dimerisation domain Dna2 PF08696.11 OWF41686.1 - 0.22 11.3 2.7 1.9 8.2 0.1 3.0 2 1 0 3 3 3 0 DNA replication factor Dna2 SR-25 PF10500.9 OWF41686.1 - 5.3 6.6 13.9 11 5.6 13.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_BLLF1 PF05109.13 OWF41687.1 - 1.1e-56 192.5 44.7 1e-09 37.0 2.5 7.0 1 1 6 7 7 7 7 Herpes virus major outer envelope glycoprotein (BLLF1) DUF951 PF06107.11 OWF41688.1 - 0.0086 16.0 9.9 0.66 9.9 1.9 3.2 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF951) TRAM_2 PF18693.1 OWF41688.1 - 0.011 15.9 8.2 2.4 8.4 0.2 3.1 3 0 0 3 3 3 0 TRAM domain S_layer_N PF05123.12 OWF41688.1 - 0.035 14.0 0.0 0.68 9.7 0.0 2.0 1 1 0 1 1 1 0 S-layer like family, N-terminal region DUF5496 PF17600.2 OWF41688.1 - 0.17 11.9 1.0 15 5.7 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5496) DUF321 PF03778.13 OWF41688.1 - 0.19 11.4 1.9 24 4.7 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF321) YccF PF03733.13 OWF41688.1 - 0.92 10.3 6.3 54 4.6 0.2 3.7 1 1 0 2 2 2 0 Inner membrane component domain ZapA PF05164.13 OWF41688.1 - 1.5 9.3 7.5 56 4.3 0.3 4.3 1 1 4 5 5 5 0 Cell division protein ZapA Patatin PF01734.22 OWF41689.1 - 8.7e-25 88.1 0.0 2.3e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase EF-hand_1 PF00036.32 OWF41689.1 - 1.1e-09 37.2 1.3 0.00097 18.5 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF41689.1 - 1.3e-09 37.2 2.0 0.0012 18.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF41689.1 - 1.8e-07 31.5 1.6 6.4e-07 29.7 1.6 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF41689.1 - 4.3e-05 22.8 0.7 0.088 12.3 0.7 2.6 2 0 0 2 2 2 2 EF hand EVC2_like PF12297.8 OWF41689.1 - 0.016 13.9 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein EF-hand_8 PF13833.6 OWF41689.1 - 0.1 12.4 0.4 8.3 6.4 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain pair RuvA_C PF07499.13 OWF41689.1 - 0.21 12.1 0.3 8.7 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain DUF4203 PF13886.6 OWF41690.1 - 7.8e-25 87.7 32.7 1.2e-24 87.1 32.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) MMPL PF03176.15 OWF41690.1 - 2.3 7.1 5.5 5.6 5.8 5.5 1.6 1 0 0 1 1 1 0 MMPL family DUF2948 PF11164.8 OWF41691.1 - 3.5e-06 27.1 11.2 24 4.9 0.1 7.7 1 1 8 10 10 10 2 Protein of unknown function (DUF2948) CarD_CdnL_TRCF PF02559.16 OWF41691.1 - 0.00071 20.2 42.0 26 5.6 0.2 10.9 1 1 6 7 7 7 3 CarD-like/TRCF domain Rtt106 PF08512.12 OWF41691.1 - 0.011 16.1 0.1 1.2e+02 3.2 0.0 5.0 1 1 4 6 6 6 0 Histone chaperone Rttp106-like Vps53_N PF04100.12 OWF41691.1 - 0.097 11.6 2.1 5.2 5.9 0.3 2.7 1 1 1 3 3 3 0 Vps53-like, N-terminal DUF1919 PF08942.10 OWF41691.1 - 0.31 10.5 31.2 26 4.2 1.2 9.1 1 1 8 9 9 9 0 Domain of unknown function (DUF1919) DUF1232 PF06803.12 OWF41691.1 - 0.33 10.8 31.4 69 3.4 0.0 11.7 13 0 0 13 13 13 0 Protein of unknown function (DUF1232) Peptidase_S8 PF00082.22 OWF41693.1 - 2.4e-40 138.7 3.5 3.4e-40 138.2 3.5 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OWF41693.1 - 2.2e-22 78.9 0.1 6.2e-22 77.4 0.1 1.9 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OWF41693.1 - 7.4e-16 58.7 0.1 2.5e-15 57.0 0.1 1.9 2 0 0 2 2 2 1 Peptidase S8 pro-domain Lys PF00062.20 OWF41694.1 - 0.15 12.3 4.6 1.3 9.3 1.1 2.4 1 1 2 3 3 3 0 C-type lysozyme/alpha-lactalbumin family CholecysA-Rec_N PF09193.10 OWF41694.1 - 0.27 11.3 8.6 39 4.4 2.4 4.2 1 1 2 3 3 3 0 Cholecystokinin A receptor, N-terminal Pkinase PF00069.25 OWF41695.1 - 2.5e-67 227.0 0.0 2.9e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41695.1 - 8.2e-42 143.3 0.0 1e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF41695.1 - 6.1e-10 38.9 0.0 8.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OWF41695.1 - 0.0038 16.8 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OWF41695.1 - 0.0046 16.3 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF41695.1 - 0.0073 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OWF41695.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Annexin PF00191.20 OWF41696.1 - 1.8e-72 239.3 19.9 2.1e-13 50.1 0.4 8.3 8 0 0 8 8 8 8 Annexin KIAA1430 PF13879.6 OWF41696.1 - 9.5e-17 61.6 7.4 9.5e-17 61.6 7.4 3.7 4 0 0 4 4 4 1 KIAA1430 homologue DUF1400 PF07176.11 OWF41696.1 - 0.091 13.0 0.1 0.33 11.2 0.1 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) TrbI_Ftype PF09677.10 OWF41696.1 - 0.13 12.6 0.0 0.56 10.6 0.0 2.2 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) TTL PF03133.15 OWF41697.1 - 5.4e-47 160.3 2.2 9.6e-47 159.5 2.2 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF41697.1 - 0.026 13.8 0.2 0.064 12.5 0.0 1.7 2 0 0 2 2 2 0 YheC/D like ATP-grasp DUF3379 PF11859.8 OWF41697.1 - 0.14 11.5 0.0 0.8 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) Rad51 PF08423.11 OWF41698.1 - 5.5e-62 209.3 0.0 6.1e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OWF41698.1 - 0.018 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 OWF41698.1 - 0.021 14.8 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain ICA69 PF04629.14 OWF41699.1 - 0.087 13.1 0.2 0.1 12.9 0.2 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain zf-U11-48K PF05253.12 OWF41701.1 - 4.1e-18 64.9 10.8 1.7e-09 37.4 1.5 2.5 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger LRR_11 PF18831.1 OWF41702.1 - 2.5e-05 23.7 4.7 12 5.6 0.0 6.5 7 0 0 7 7 7 1 Leucine-rich repeat SAYSvFN PF10260.9 OWF41702.1 - 0.0003 20.6 1.1 9.2 6.3 0.0 5.7 1 1 6 7 7 7 1 Uncharacterized conserved domain (SAYSvFN) YaiA PF16362.5 OWF41702.1 - 0.0025 17.9 1.0 41 4.4 0.0 4.8 2 2 2 5 5 5 0 YaiA protein DUF4079 PF13301.6 OWF41702.1 - 0.24 11.5 15.4 8.6 6.5 1.0 4.9 2 1 2 4 4 4 0 Protein of unknown function (DUF4079) Metalloenzyme PF01676.18 OWF41702.1 - 0.3 10.4 17.1 6.5 6.0 0.1 6.1 2 1 3 5 5 5 0 Metalloenzyme superfamily MAPEG PF01124.18 OWF41702.1 - 0.43 10.5 7.8 19 5.1 0.0 4.8 2 1 4 6 6 6 0 MAPEG family PRKCSH PF07915.13 OWF41703.1 - 2.4e-16 60.5 6.2 2.4e-16 60.5 6.2 3.6 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 OWF41703.1 - 0.00012 21.8 6.0 0.00035 20.3 0.5 3.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF501 PF04417.12 OWF41703.1 - 0.45 10.3 13.0 2.2 8.1 0.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF501) zf-C3HC4_3 PF13920.6 OWF41704.1 - 4.4e-13 48.9 14.1 4.4e-13 48.9 14.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF41704.1 - 9.2e-05 22.3 15.9 0.00032 20.6 15.9 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF41704.1 - 0.00011 22.4 14.9 0.00031 21.0 14.9 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OWF41704.1 - 0.0014 18.5 13.4 0.0028 17.5 13.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PMP22_Claudin PF00822.20 OWF41704.1 - 0.0014 18.5 8.3 0.0025 17.7 8.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF41704.1 - 0.086 12.6 21.6 0.069 12.9 13.2 3.3 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction zf-C3HC4_2 PF13923.6 OWF41704.1 - 0.2 11.5 14.5 0.59 10.0 14.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41704.1 - 2.7 8.1 13.3 10 6.2 8.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 OWF41704.1 - 9.2 6.1 13.7 35 4.3 13.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0515 PF15135.6 OWF41705.1 - 1.6e-47 162.1 10.4 2e-47 161.8 10.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-3CxxC_2 PF17180.4 OWF41705.1 - 0.029 15.1 14.7 0.4 11.5 3.0 3.0 1 1 2 3 3 3 0 Zinc-binding domain zf_CopZ PF18423.1 OWF41705.1 - 0.17 11.9 2.9 1.7 8.6 0.2 2.6 2 0 0 2 2 2 0 Zinc binding domain Lipase_GDSL_2 PF13472.6 OWF41706.1 - 0.0002 21.8 0.0 0.00025 21.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ras PF00071.22 OWF41707.1 - 1.9e-42 144.6 1.1 2.2e-42 144.4 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF41707.1 - 1.9e-17 63.6 0.1 3.1e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OWF41707.1 - 5.1e-06 26.2 0.9 9.6e-06 25.3 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF41707.1 - 2.9e-05 24.1 2.1 0.12 12.3 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 OWF41707.1 - 3.2e-05 23.4 0.1 3.8e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF41707.1 - 0.00084 19.4 0.1 0.0017 18.4 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF41707.1 - 0.0013 18.2 0.2 0.0028 17.1 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OWF41707.1 - 0.0041 16.9 0.8 1 9.1 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OWF41707.1 - 0.0086 16.4 0.2 0.052 13.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 OWF41707.1 - 0.01 15.3 0.1 0.034 13.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AIG1 PF04548.16 OWF41707.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 OWF41707.1 - 0.015 14.8 2.2 0.34 10.4 2.2 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 OWF41707.1 - 0.027 14.9 0.0 0.065 13.6 0.0 1.7 2 0 0 2 2 1 0 RNA helicase DAP3 PF10236.9 OWF41707.1 - 0.036 13.2 0.2 0.14 11.3 0.0 1.9 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 OWF41707.1 - 0.054 13.2 0.0 0.58 9.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OWF41707.1 - 0.1 12.2 0.0 0.43 10.1 0.0 1.9 2 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OWF41707.1 - 0.1 12.6 0.0 0.56 10.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) EBA-175_VI PF11556.8 OWF41707.1 - 0.11 12.8 1.1 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Erythrocyte binding antigen 175 AAA_16 PF13191.6 OWF41707.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain CIDE-N PF02017.15 OWF41709.1 - 6.4e-29 99.8 0.2 5.9e-12 45.4 0.1 3.6 3 0 0 3 3 3 3 CIDE-N domain Sushi PF00084.20 OWF41709.1 - 0.0051 17.4 0.8 0.011 16.4 0.0 2.0 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) Sushi PF00084.20 OWF41710.1 - 8.8e-07 29.4 0.0 1.9e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) TMEM132D_C PF15706.5 OWF41710.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Sarcoglycan_2 PF05510.13 OWF41710.1 - 0.18 10.5 0.2 0.34 9.6 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Peptidase_C14 PF00656.22 OWF41711.1 - 1.4e-27 97.3 0.0 2.4e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Caspase domain PPP4R2 PF09184.11 OWF41711.1 - 0.042 13.4 2.7 0.056 13.0 2.7 1.2 1 0 0 1 1 1 0 PPP4R2 Peptidase_C14 PF00656.22 OWF41712.1 - 5.2e-30 105.2 0.0 1.9e-29 103.4 0.0 1.7 1 1 0 1 1 1 1 Caspase domain PPP4R2 PF09184.11 OWF41712.1 - 0.0032 17.1 8.4 0.0045 16.6 8.4 1.2 1 0 0 1 1 1 1 PPP4R2 BUD22 PF09073.10 OWF41712.1 - 0.052 12.9 10.2 0.079 12.3 10.2 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OWF41712.1 - 1.2 7.2 14.0 1.7 6.8 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OWF41712.1 - 6 5.0 12.9 8 4.6 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RlaP PF10127.9 OWF41713.1 - 6e-18 65.3 0.0 2.2e-17 63.5 0.0 1.9 2 0 0 2 2 2 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 OWF41713.1 - 0.00078 19.7 0.0 0.0021 18.3 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OWF41713.1 - 0.079 13.1 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase LRR_6 PF13516.6 OWF41714.1 - 3.3e-10 39.2 9.6 0.0052 16.7 0.2 5.3 5 0 0 5 5 5 4 Leucine Rich repeat DnaJ_C PF01556.18 OWF41715.1 - 3e-45 153.9 1.6 4.4e-45 153.4 1.1 1.5 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 OWF41715.1 - 1.6e-25 89.0 1.3 2.9e-25 88.1 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OWF41715.1 - 1.1e-14 54.5 19.8 2e-14 53.7 19.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 OWF41715.1 - 0.044 13.8 6.6 0.5 10.4 1.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 OWF41715.1 - 0.34 10.9 10.9 2.4 8.2 2.2 3.1 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Gin PF10764.9 OWF41715.1 - 1.1 9.3 4.4 26 4.9 1.5 2.5 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin TackOD1 PF18551.1 OWF41715.1 - 1.8 8.2 6.2 2.2 7.9 1.0 2.2 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 EF-hand_7 PF13499.6 OWF41716.1 - 0.00016 22.0 0.1 0.0002 21.8 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF41716.1 - 0.00045 19.9 0.8 0.00085 19.1 0.8 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OWF41716.1 - 0.00072 18.9 1.5 0.0011 18.3 1.5 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OWF41716.1 - 0.063 12.8 0.4 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 EF hand zf-C3HC4 PF00097.25 OWF41717.1 - 1.9e-05 24.5 10.9 1.9e-05 24.5 10.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF41717.1 - 0.00011 22.4 25.0 0.0008 19.7 10.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 OWF41717.1 - 0.0002 21.3 8.1 0.0002 21.3 8.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF41717.1 - 0.00052 19.9 24.3 0.00083 19.3 8.9 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-B_box PF00643.24 OWF41717.1 - 0.0025 17.9 8.8 0.0025 17.9 8.8 3.0 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_2 PF13923.6 OWF41717.1 - 0.025 14.4 11.2 0.025 14.4 11.2 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 OWF41717.1 - 0.15 12.3 16.0 1.2 9.4 4.2 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger zinc_ribbon_5 PF13719.6 OWF41717.1 - 0.21 11.4 0.2 0.21 11.4 0.2 3.4 3 1 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_4 PF15227.6 OWF41717.1 - 0.33 11.1 22.4 0.61 10.3 11.3 3.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF5447 PF17525.2 OWF41717.1 - 1.1 9.8 14.0 1.7 9.2 4.5 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5447) Prok-RING_4 PF14447.6 OWF41717.1 - 2.7 7.9 21.4 0.13 12.2 9.4 3.2 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 OWF41717.1 - 8.2 6.7 24.4 3.3 8.0 10.9 3.2 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain NHL PF01436.21 OWF41718.1 - 4.5e-05 23.3 0.7 0.055 13.5 0.0 4.2 5 0 0 5 5 5 1 NHL repeat FUSC-like PF12805.7 OWF41718.1 - 0.029 13.5 0.2 0.043 12.9 0.2 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF3552 PF12072.8 OWF41719.1 - 1.2 8.5 22.6 1.9 7.9 4.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) DUF724 PF05266.14 OWF41719.1 - 1.6 8.5 22.2 0.56 10.0 3.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) SNARE PF05739.19 OWF41719.1 - 1.7 8.7 27.0 1.5 8.9 2.1 4.9 4 1 0 4 4 4 0 SNARE domain PspA_IM30 PF04012.12 OWF41719.1 - 4.5 6.8 13.9 4.3 6.8 1.4 3.1 2 1 1 3 3 3 0 PspA/IM30 family FPP PF05911.11 OWF41719.1 - 6.2 4.9 29.7 7.4 4.6 29.7 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Glutaredoxin2_C PF04399.13 OWF41719.1 - 6.6 6.6 15.1 6.8 6.5 1.6 3.6 1 1 3 4 4 4 0 Glutaredoxin 2, C terminal domain DUF745 PF05335.13 OWF41719.1 - 6.7 6.4 19.3 10 5.8 8.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) zf-C3HC4 PF00097.25 OWF41720.1 - 1.4e-08 34.5 6.0 1.4e-08 34.5 6.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF41720.1 - 7.2e-08 32.5 30.9 0.00017 21.7 6.2 3.8 4 0 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF41720.1 - 1.1e-07 31.8 4.3 1.1e-07 31.8 4.3 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF41720.1 - 1.2e-06 28.8 6.1 1.2e-06 28.8 6.1 3.2 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 OWF41720.1 - 2.2e-06 27.5 4.7 2.2e-06 27.5 4.7 3.2 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF41720.1 - 5.7e-05 23.2 6.3 5.7e-05 23.2 6.3 3.7 4 1 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF41720.1 - 0.00038 20.3 8.5 0.00038 20.3 8.5 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41720.1 - 0.00086 19.1 4.9 0.00086 19.1 4.9 3.8 3 2 0 3 3 3 1 Prokaryotic RING finger family 4 DUF5447 PF17525.2 OWF41720.1 - 3.9 8.0 12.8 0.46 11.0 1.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5447) Arginosuc_synth PF00764.19 OWF41721.1 - 6.9e-157 522.7 0.0 7.8e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OWF41721.1 - 0.0003 20.3 0.0 0.00061 19.3 0.0 1.5 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OWF41721.1 - 0.0083 14.9 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Acyl_transf_3 PF01757.22 OWF41722.1 - 7.9e-22 77.8 43.9 1.5e-21 76.9 43.9 1.4 1 0 0 1 1 1 1 Acyltransferase family COR PF16095.5 OWF41723.1 - 3e-11 43.5 0.2 1.7e-10 41.0 0.1 2.1 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF41723.1 - 4.8e-11 42.9 0.0 3.9e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF41723.1 - 8.2e-09 35.5 0.1 5.9e-05 23.1 0.0 2.9 2 0 0 2 2 2 2 Death domain Arf PF00025.21 OWF41723.1 - 0.00082 18.9 0.0 0.052 13.0 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.6 OWF41723.1 - 0.008 16.4 0.1 0.057 13.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain Ras PF00071.22 OWF41723.1 - 0.0082 15.8 0.0 0.084 12.5 0.0 2.3 2 0 0 2 2 2 1 Ras family G-alpha PF00503.20 OWF41723.1 - 0.029 13.6 0.1 1.4 8.0 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 OWF41723.1 - 0.069 13.7 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OWF41723.1 - 0.12 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OWF41723.1 - 0.13 11.6 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 OWF41724.1 - 2e-24 86.5 0.1 1.2e-23 84.0 0.0 2.2 2 0 0 2 2 2 1 TIR domain Arm PF00514.23 OWF41724.1 - 1.6e-10 40.6 0.0 4.1e-07 29.8 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF41724.1 - 0.0015 18.8 0.2 4 7.9 0.0 3.2 2 1 0 3 3 3 2 HEAT repeats TIR PF01582.20 OWF41724.1 - 0.0028 17.5 0.6 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 TIR domain HEAT PF02985.22 OWF41724.1 - 0.0064 16.6 0.0 54 4.4 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 OWF41724.1 - 0.033 14.7 0.2 16 6.2 0.1 3.2 3 0 0 3 3 3 0 HEAT-like repeat DUF4062 PF13271.6 OWF41724.1 - 0.044 14.1 0.5 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) Nuc_deoxyri_tr3 PF11071.8 OWF41724.1 - 0.095 12.8 5.2 0.29 11.2 0.1 3.2 3 1 1 4 4 4 0 Nucleoside 2-deoxyribosyltransferase YtoQ SAM_3 PF18016.1 OWF41724.1 - 0.16 11.8 0.4 0.44 10.4 0.4 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TIR PF01582.20 OWF41725.1 - 6.2e-21 75.0 0.0 9.1e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF41725.1 - 2.3e-19 70.1 0.0 3.1e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain EGF_2 PF07974.13 OWF41725.1 - 0.00043 20.6 5.9 0.00062 20.1 5.9 1.3 1 0 0 1 1 1 1 EGF-like domain TarS_C1 PF18674.1 OWF41725.1 - 0.0097 15.8 0.2 0.021 14.7 0.2 1.5 1 0 0 1 1 1 1 TarS beta-glycosyltransferase C-terminal domain 1 DUF4448 PF14610.6 OWF41725.1 - 0.068 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) 60KD_IMP PF02096.20 OWF41725.1 - 0.093 12.6 2.1 0.099 12.5 0.2 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein DUF4062 PF13271.6 OWF41725.1 - 0.14 12.6 0.0 1.1 9.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4062) Laminin_EGF PF00053.24 OWF41725.1 - 0.23 11.6 5.5 0.39 10.9 5.5 1.3 1 0 0 1 1 1 0 Laminin EGF domain EGF PF00008.27 OWF41725.1 - 0.32 11.3 3.4 0.59 10.5 3.4 1.5 1 0 0 1 1 1 0 EGF-like domain SKG6 PF08693.10 OWF41725.1 - 1.5 8.3 3.6 2.9 7.4 3.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TRAM_LAG1_CLN8 PF03798.16 OWF41726.1 - 1.1e-24 87.3 20.6 1.1e-24 87.3 20.6 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OWF41726.1 - 1.2e-18 66.5 0.1 3e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein S1FA PF04689.13 OWF41726.1 - 6.3 7.0 6.0 62 3.8 0.3 3.9 3 0 0 3 3 3 0 DNA binding protein S1FA Drf_FH1 PF06346.12 OWF41727.1 - 0.0011 18.7 4.4 0.0013 18.5 4.4 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 DUF1242 PF06842.12 OWF41727.1 - 0.2 11.5 8.7 3.2e+02 1.2 5.0 6.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1242) WRNPLPNID PF15017.6 OWF41727.1 - 0.76 10.7 5.6 3e+02 2.4 0.1 5.6 5 1 2 7 7 7 0 Putative WW-binding domain and destruction box dDENN PF03455.19 OWF41728.1 - 5.2e-05 23.1 28.3 3.2 7.8 0.2 13.3 3 2 12 20 20 20 6 dDENN domain IBR PF01485.21 OWF41729.1 - 6.4e-13 48.7 40.2 1.6e-08 34.6 11.2 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 OWF41730.1 - 0.25 11.4 10.6 0.065 13.2 7.2 1.8 2 1 1 3 3 3 0 zinc-ribbons Ribosomal_S27e PF01667.17 OWF41730.1 - 4.7 7.0 11.4 0.3 10.8 3.9 2.5 2 1 1 3 3 3 0 Ribosomal protein S27 CAMSAP_CKK PF08683.11 OWF41731.1 - 1.1e-53 180.4 0.3 2e-53 179.6 0.3 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 OWF41731.1 - 1.5e-24 85.6 0.1 4.6e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 OWF41731.1 - 3.8e-18 65.1 6.1 3.8e-18 65.1 6.1 2.6 2 0 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin THEG PF14912.6 OWF41732.1 - 5.1e-38 129.3 19.6 8e-15 55.0 0.0 4.9 3 2 3 6 6 6 6 Testicular haploid expressed repeat DUF3072 PF11272.8 OWF41732.1 - 0.1 12.5 0.1 1 9.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) NAPRTase_N PF17767.1 OWF41734.1 - 3.1e-39 134.2 0.1 7.4e-39 133.0 0.1 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 OWF41734.1 - 1.2e-29 103.0 0.0 2.2e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 OWF41734.1 - 1.8e-08 34.3 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 OWF41734.1 - 0.12 12.5 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Sec6 PF06046.13 OWF41735.1 - 2.1e-109 366.5 6.3 2.1e-109 366.5 6.3 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 CAMP_factor PF07373.11 OWF41735.1 - 0.0081 15.8 0.4 0.018 14.6 0.2 1.7 1 1 0 1 1 1 1 CAMP factor (Cfa) NPV_P10 PF05531.12 OWF41735.1 - 0.011 16.2 0.4 0.043 14.3 0.4 2.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.14 OWF41735.1 - 0.028 14.3 1.3 0.093 12.6 1.3 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TBCC_N PF16752.5 OWF41735.1 - 0.059 13.8 3.5 0.3 11.5 3.5 2.3 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Sec5 PF15469.6 OWF41735.1 - 0.092 12.5 4.3 0.15 11.8 2.6 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 TBCA PF02970.16 OWF41735.1 - 0.66 10.3 7.1 0.093 13.1 0.7 3.1 3 0 0 3 3 3 0 Tubulin binding cofactor A Cytochrom_B562 PF07361.11 OWF41735.1 - 0.7 10.6 4.0 13 6.5 0.6 3.0 1 1 1 2 2 2 0 Cytochrome b562 SOAR PF16533.5 OWF41735.1 - 1.9 8.5 5.9 0.62 10.1 1.1 2.7 2 1 0 2 2 2 0 STIM1 Orai1-activating region Prefoldin_2 PF01920.20 OWF41735.1 - 3.4 7.7 13.6 0.45 10.5 0.7 3.7 3 0 0 3 3 3 0 Prefoldin subunit SAND PF01342.21 OWF41736.1 - 5.6e-19 67.6 0.0 9.1e-19 66.9 0.0 1.3 1 0 0 1 1 1 1 SAND domain HscB_4_cys PF18256.1 OWF41736.1 - 0.13 12.1 0.4 0.25 11.2 0.4 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif TMEM132D_C PF15706.5 OWF41737.1 - 8.4e-05 22.3 0.7 0.00048 19.8 0.0 2.2 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SpoIIIAH PF12685.7 OWF41737.1 - 0.00063 19.6 0.5 0.00088 19.2 0.5 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein Amnionless PF14828.6 OWF41737.1 - 0.0023 16.9 0.2 0.0028 16.5 0.2 1.1 1 0 0 1 1 1 1 Amnionless Glycophorin_A PF01102.18 OWF41737.1 - 0.0024 18.1 1.0 0.0048 17.1 0.1 1.9 1 1 1 2 2 2 1 Glycophorin A SARAF PF06682.12 OWF41737.1 - 0.0026 17.5 0.2 0.0037 17.0 0.2 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF5527 PF17665.1 OWF41737.1 - 0.007 15.9 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5527) Syndecan PF01034.20 OWF41737.1 - 0.0084 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain Neur_chan_memb PF02932.16 OWF41737.1 - 0.0086 16.2 0.7 0.011 15.8 0.5 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4731 PF15875.5 OWF41737.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) Cadherin_C_2 PF16492.5 OWF41737.1 - 0.018 15.8 0.0 0.031 15.0 0.0 1.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal O-antigen_lig PF13425.6 OWF41737.1 - 0.025 13.4 2.5 0.031 13.1 2.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Zip PF02535.22 OWF41737.1 - 0.026 13.7 1.1 0.035 13.3 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MAP17 PF15807.5 OWF41737.1 - 0.027 14.7 7.2 2 8.6 7.2 2.3 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3835 PF12927.7 OWF41737.1 - 0.046 14.6 2.0 0.046 14.6 2.0 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF3835) DUF4446 PF14584.6 OWF41737.1 - 0.1 12.6 2.7 0.28 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF202 PF02656.15 OWF41737.1 - 0.12 12.9 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TRP PF06011.12 OWF41737.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Comm PF15957.5 OWF41737.1 - 0.15 12.5 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 Commissureless DUF2615 PF11027.8 OWF41737.1 - 0.24 11.6 2.5 0.95 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) EphA2_TM PF14575.6 OWF41737.1 - 0.32 11.9 1.3 1.6 9.7 1.3 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 OWF41737.1 - 0.55 11.2 8.4 26 5.8 8.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2207 PF09972.9 OWF41737.1 - 9.4 4.9 8.5 0.24 10.1 0.8 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) OATP PF03137.20 OWF41738.1 - 3.2e-121 405.3 20.4 3.2e-121 405.3 20.4 1.5 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF41738.1 - 6.4e-11 41.8 30.6 4.9e-09 35.6 15.5 3.3 3 1 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF41738.1 - 1.8e-06 28.0 13.0 5.2e-06 26.5 13.0 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF41738.1 - 0.021 14.8 4.8 0.06 13.4 4.8 1.7 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain OATP PF03137.20 OWF41739.1 - 9e-128 426.9 15.0 1.2e-127 426.5 15.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF41739.1 - 1e-15 57.6 24.2 2.9e-13 49.5 8.9 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF41739.1 - 2e-05 24.6 9.0 4.7e-05 23.4 9.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF41739.1 - 0.046 13.7 3.4 0.14 12.2 3.4 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Cadherin PF00028.17 OWF41740.1 - 7.7e-35 119.2 12.8 1.8e-07 31.5 0.1 6.3 6 0 0 6 6 6 6 Cadherin domain Renin_r PF07850.14 OWF41740.1 - 0.067 13.8 0.6 0.39 11.4 0.0 2.3 2 0 0 2 2 2 0 Renin receptor-like protein Cadherin_pro PF08758.11 OWF41740.1 - 0.11 12.7 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Cadherin prodomain like Cadherin PF00028.17 OWF41741.1 - 1e-23 83.5 9.3 1.5e-05 25.3 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain PMT_4TMC PF16192.5 OWF41741.1 - 0.054 13.1 3.1 0.16 11.5 3.1 1.7 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase OATP PF03137.20 OWF41742.1 - 6.1e-128 427.5 14.2 7.1e-128 427.3 14.2 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF41742.1 - 9.1e-19 67.6 9.0 9.1e-19 67.6 9.0 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF41742.1 - 0.00016 21.7 12.0 0.00038 20.5 12.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF41742.1 - 0.0046 16.9 2.8 0.013 15.5 2.8 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Lectin_C PF00059.21 OWF41743.1 - 0.00091 19.9 0.0 0.0018 18.9 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain DUF4515 PF14988.6 OWF41743.1 - 0.0083 16.0 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Ras PF00071.22 OWF41744.1 - 1.4e-39 135.3 1.0 1.9e-39 134.9 1.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF41744.1 - 3.6e-24 85.3 0.3 5.2e-24 84.8 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF41744.1 - 3.4e-16 59.2 0.1 4.9e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.31 OWF41744.1 - 8.6e-10 38.6 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain MMR_HSR1 PF01926.23 OWF41744.1 - 8.8e-05 22.6 0.1 0.00019 21.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF41744.1 - 0.00023 20.7 0.4 0.0013 18.3 0.3 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF41744.1 - 0.003 16.9 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3048_C PF17479.2 OWF41744.1 - 0.066 13.6 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain DUF241 PF03087.14 OWF41744.1 - 0.14 12.0 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Arabidopsis protein of unknown function HrpA_pilin PF09589.10 OWF41744.1 - 0.14 12.9 0.4 0.7 10.6 0.1 2.0 2 0 0 2 2 2 0 HrpA pilus formation protein FAD_binding_1 PF00667.20 OWF41745.1 - 4.2e-38 131.1 0.1 5.8e-38 130.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OWF41745.1 - 6.3e-20 71.9 0.0 1.6e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 OWF41745.1 - 2.8e-18 66.5 0.0 8.6e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin RVT_1 PF00078.27 OWF41746.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Anoctamin PF04547.12 OWF41747.1 - 0.0028 16.6 1.5 0.0033 16.3 1.5 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_13 PF17958.1 OWF41747.1 - 0.014 15.2 0.1 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain fn3 PF00041.21 OWF41748.1 - 1.6e-12 47.6 8.5 3e-06 27.5 0.7 5.3 4 1 1 5 5 5 3 Fibronectin type III domain ig PF00047.25 OWF41748.1 - 0.071 13.3 0.8 0.18 12.0 0.2 2.1 2 0 0 2 2 2 0 Immunoglobulin domain Daxx PF03344.15 OWF41748.1 - 0.084 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain Pur_ac_phosph_N PF16656.5 OWF41748.1 - 5.9 7.5 8.0 2 9.0 1.8 3.3 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Gly-zipper_YMGG PF13441.6 OWF41748.1 - 7.8 6.3 6.3 13 5.7 6.3 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper PQQ PF01011.21 OWF41749.1 - 0.034 14.1 22.4 17 5.6 0.1 7.9 1 1 8 9 9 9 0 PQQ enzyme repeat RNase_Zc3h12a PF11977.8 OWF41749.1 - 0.036 13.8 9.3 3 7.6 0.9 4.0 1 1 2 3 3 3 0 Zc3h12a-like Ribonuclease NYN domain SEA PF01390.20 OWF41749.1 - 0.043 13.9 9.9 0.66 10.1 0.4 3.4 1 1 2 3 3 3 0 SEA domain DUF4907 PF16250.5 OWF41749.1 - 0.052 13.4 5.8 53 3.8 0.0 5.3 1 1 4 7 7 7 0 Domain of unknown function (DUF4907) V-set PF07686.17 OWF41749.1 - 0.074 13.2 6.1 2.6 8.3 1.1 2.5 1 1 2 3 3 3 0 Immunoglobulin V-set domain MuF_C PF18819.1 OWF41749.1 - 0.11 12.5 15.5 6.9 6.7 0.5 4.0 1 1 3 4 4 4 0 Phage MuF-C-terminal domain GPI-anchored PF10342.9 OWF41749.1 - 0.19 12.5 3.7 7.4 7.4 0.9 3.0 1 1 2 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SCAB-PH PF17684.1 OWF41749.1 - 0.22 11.8 2.7 6 7.1 0.1 2.9 1 1 3 4 4 4 0 PH domain of plant-specific actin-binding protein FlhE PF06366.13 OWF41749.1 - 0.29 11.1 11.7 24 5.0 0.1 4.3 1 1 4 5 5 5 0 Flagellar protein FlhE STE3 PF02076.15 OWF41749.1 - 3.5 6.8 29.3 2.1 7.5 4.9 3.0 1 1 2 3 3 3 0 Pheromone A receptor Lep_receptor_Ig PF06328.11 OWF41749.1 - 8.8 6.4 15.0 30 4.7 0.4 4.9 1 1 4 5 5 5 0 Ig-like C2-type domain PQQ PF01011.21 OWF41750.1 - 0.00047 20.0 7.0 6 7.0 0.1 4.1 1 1 3 4 4 4 3 PQQ enzyme repeat DUF1961 PF09224.11 OWF41750.1 - 0.011 15.1 0.8 0.72 9.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1961) RNase_Zc3h12a PF11977.8 OWF41750.1 - 0.018 14.9 1.1 3.5 7.4 0.1 2.0 1 1 1 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain DUF4907 PF16250.5 OWF41750.1 - 0.044 13.7 1.8 54 3.8 0.0 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4907) Cyclase_polyket PF04673.12 OWF41750.1 - 0.073 13.3 0.0 25 5.2 0.0 2.3 1 1 2 3 3 3 0 Polyketide synthesis cyclase MuF_C PF18819.1 OWF41750.1 - 0.4 10.7 6.6 6.5 6.8 1.7 2.2 1 1 1 2 2 2 0 Phage MuF-C-terminal domain Lep_receptor_Ig PF06328.11 OWF41750.1 - 1.4 8.9 6.2 35 4.5 0.2 3.2 1 1 3 4 4 4 0 Ig-like C2-type domain STE3 PF02076.15 OWF41750.1 - 6.3 5.9 9.9 7 5.8 9.2 1.5 1 1 0 1 1 1 0 Pheromone A receptor EF-hand_4 PF12763.7 OWF41752.1 - 5e-25 87.4 0.1 3.1e-12 46.3 0.1 3.0 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand COR PF16095.5 OWF41752.1 - 1.9e-17 63.8 0.0 4.6e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF41752.1 - 1.3e-12 48.0 0.3 1.8e-07 31.4 0.0 3.5 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase SH2 PF00017.24 OWF41752.1 - 1e-10 41.5 0.3 0.00051 20.1 0.0 3.3 3 0 0 3 3 3 2 SH2 domain Death PF00531.22 OWF41752.1 - 3.5e-09 36.7 0.0 8.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Death domain EF-hand_1 PF00036.32 OWF41752.1 - 8.9e-09 34.3 3.5 0.0013 18.2 0.3 3.4 3 0 0 3 3 2 2 EF hand Macro PF01661.21 OWF41752.1 - 6.7e-07 29.4 0.0 1.9e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Macro domain AAA_18 PF13238.6 OWF41752.1 - 0.0015 19.0 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain EF-hand_6 PF13405.6 OWF41752.1 - 0.0016 18.2 2.8 0.55 10.3 0.2 4.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OWF41752.1 - 0.002 18.5 8.1 0.16 12.5 0.4 4.1 4 0 0 4 4 4 2 EF-hand domain pair AAA_22 PF13401.6 OWF41752.1 - 0.0022 18.2 0.0 0.0063 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 OWF41752.1 - 0.028 14.0 0.1 4.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Ras family ABC_tran PF00005.27 OWF41752.1 - 0.03 14.8 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OWF41752.1 - 0.033 14.6 0.0 0.09 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OWF41752.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation EF-hand_5 PF13202.6 OWF41752.1 - 0.074 12.6 0.0 0.31 10.6 0.0 2.1 1 0 0 1 1 1 0 EF hand MMR_HSR1 PF01926.23 OWF41752.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 OWF41752.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 OWF41752.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OWF41752.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase AAA_5 PF07728.14 OWF41752.1 - 0.16 12.0 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Microtub_bd PF16796.5 OWF41752.1 - 0.16 11.9 0.1 28 4.6 0.0 3.2 3 0 0 3 3 3 0 Microtubule binding EF-hand_8 PF13833.6 OWF41752.1 - 0.27 11.1 2.2 0.93 9.4 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair Retrotrans_gag PF03732.17 OWF41754.1 - 0.021 15.1 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein AA_kinase PF00696.28 OWF41755.1 - 1e-47 162.8 0.9 1.2e-47 162.5 0.9 1.0 1 0 0 1 1 1 1 Amino acid kinase family Methyltransf_16 PF10294.9 OWF41756.1 - 7.9e-06 25.7 0.0 1e-05 25.3 0.0 1.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OWF41756.1 - 0.016 15.1 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OWF41756.1 - 0.019 14.8 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2251 PF10008.9 OWF41756.1 - 0.029 14.4 0.3 0.05 13.7 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) AgI_II_C2 PF17998.1 OWF41757.1 - 5.4e-12 46.4 99.3 57 4.0 0.1 26.9 1 1 27 28 28 28 25 Cell surface antigen I/II C2 terminal domain AIMP2_LysRS_bd PF16780.5 OWF41757.1 - 0.0013 18.4 110.1 82 3.0 0.1 26.3 28 0 0 28 28 28 26 AIMP2 lysyl-tRNA synthetase binding domain TFIIIC_delta PF12657.7 OWF41758.1 - 3.6e-27 95.5 3.4 7.4e-27 94.5 3.4 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term ANAPC4_WD40 PF12894.7 OWF41758.1 - 0.027 14.7 2.3 1 9.7 0.0 3.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Cu2_monoox_C PF03712.15 OWF41759.1 - 5.3e-21 74.8 0.0 8.1e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF41759.1 - 3e-10 40.4 0.0 5.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF41760.1 - 1.7e-21 76.4 0.5 2.9e-21 75.6 0.5 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF41760.1 - 9.1e-10 38.9 0.4 1.9e-09 37.9 0.1 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Kunitz_BPTI PF00014.23 OWF41761.1 - 1.9e-16 60.0 0.7 2.3e-16 59.8 0.7 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 OWF41762.1 - 1.9e-15 56.8 0.1 2.3e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Peptidase_M19 PF01244.21 OWF41763.1 - 4.2e-105 351.4 0.0 5.9e-105 351.0 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) 7tm_2 PF00002.24 OWF41764.1 - 1.2e-71 240.9 17.8 1.2e-71 240.9 17.8 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF41764.1 - 3.5e-16 59.3 2.4 3.5e-16 59.3 2.4 1.7 2 0 0 2 2 2 1 Hormone receptor domain DUF1461 PF07314.11 OWF41764.1 - 0.047 13.6 0.3 0.047 13.6 0.3 3.9 4 1 2 6 6 6 0 Protein of unknown function (DUF1461) TerY_C PF15616.6 OWF41764.1 - 0.2 11.8 1.5 0.55 10.4 0.1 2.2 3 0 0 3 3 3 0 TerY-C metal binding domain UL41A PF17591.2 OWF41764.1 - 0.76 9.9 4.1 0.36 11.0 0.5 2.4 2 0 0 2 2 2 0 Herpesvirus UL41A PDCD9 PF07147.12 OWF41765.1 - 5.1 6.2 105.5 1.4e+02 1.4 0.0 35.3 1 1 102 103 103 103 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) MFS_1 PF07690.16 OWF41766.1 - 7.8e-15 54.6 18.0 1.2e-09 37.6 0.5 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3176 PF11374.8 OWF41766.1 - 1.1 9.5 4.9 1.9 8.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) TraL PF07178.11 OWF41766.1 - 1.7 9.2 5.2 1.5 9.3 0.3 3.2 2 1 1 3 3 3 0 TraL protein ANATO PF01821.18 OWF41767.1 - 2.2e-06 28.4 1.5 1.7e+02 3.2 0.0 7.6 7 2 0 7 7 7 0 Anaphylotoxin-like domain zf-C2H2 PF00096.26 OWF41767.1 - 8.5e-05 22.8 22.7 41 4.9 0.1 9.1 9 0 0 9 9 9 0 Zinc finger, C2H2 type ATP-synt_ab_Xtn PF16886.5 OWF41767.1 - 0.0029 17.5 0.0 6.8 6.6 0.0 3.4 1 1 4 5 5 5 1 ATPsynthase alpha/beta subunit N-term extension DUF3218 PF11508.8 OWF41767.1 - 0.02 14.4 0.4 57 3.1 0.0 4.2 1 1 7 8 8 8 0 Protein of unknown function (DUF3218) zf-CGNR PF11706.8 OWF41767.1 - 0.039 13.8 18.0 74 3.3 0.0 7.5 6 2 1 7 7 7 0 CGNR zinc finger zf-C2H2_jaz PF12171.8 OWF41767.1 - 0.12 12.6 41.6 19 5.7 0.1 10.2 9 5 1 10 10 10 0 Zinc-finger double-stranded RNA-binding Gifsy-2 PF13856.6 OWF41767.1 - 0.22 11.9 17.1 23 5.4 0.8 4.6 1 1 2 3 3 3 0 ATP-binding sugar transporter from pro-phage DUF2434 PF10361.9 OWF41767.1 - 0.29 10.1 10.2 14 4.5 0.1 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF2434) DUF1505 PF07403.11 OWF41767.1 - 3 8.1 16.4 83 3.4 0.0 6.8 2 2 7 9 9 9 0 Protein of unknown function (DUF1505) SspH PF08141.12 OWF41768.1 - 0.00015 21.8 7.4 73 3.6 0.0 8.3 4 2 4 8 8 8 0 Small acid-soluble spore protein H family zf-TAZ PF02135.16 OWF41768.1 - 0.069 13.6 1.7 0.45 11.0 1.7 2.1 1 1 0 1 1 1 0 TAZ zinc finger HU-HIG PF18291.1 OWF41768.1 - 0.21 11.7 0.3 55 3.9 0.0 4.4 3 1 3 6 6 6 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Fucosidase_C PF16757.5 OWF41768.1 - 0.25 11.9 8.2 49 4.6 0.3 5.1 1 1 4 5 5 5 0 Alpha-L-fucosidase C-terminal domain SfsA_N PF17746.1 OWF41768.1 - 1.9 8.7 10.1 8.5 6.6 0.2 4.3 2 1 2 5 5 5 0 SfsA N-terminal OB domain NupH_GANP PF16768.5 OWF41769.1 - 2.5e-05 24.1 5.2 0.00011 22.0 5.2 1.8 1 1 0 1 1 1 1 Nucleoporin homology of Germinal-centre associated nuclear protein zf-U1 PF06220.12 OWF41769.1 - 1.9 8.3 19.1 32 4.4 1.8 5.3 1 1 2 3 3 3 0 U1 zinc finger Sulfotransfer_1 PF00685.27 OWF41770.1 - 8.8e-45 153.3 0.6 2.2e-44 152.0 0.6 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF41770.1 - 1.2e-06 29.1 0.0 3.4e-06 27.6 0.0 1.7 1 1 0 2 2 2 1 Sulfotransferase family Neur_chan_LBD PF02931.23 OWF41771.1 - 6.4e-43 146.7 1.4 8.7e-43 146.3 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41771.1 - 3.5e-24 86.2 9.8 2.8e-23 83.2 5.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF948 PF06103.11 OWF41772.1 - 2.1e-15 56.7 0.0 18 5.6 0.0 11.3 1 1 10 11 11 11 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 OWF41772.1 - 5.2e-14 52.4 2.5 32 5.0 0.0 13.7 1 1 12 15 15 15 0 Snapin/Pallidin IFT57 PF10498.9 OWF41772.1 - 7.3e-11 41.6 13.5 1.6 7.6 0.3 8.0 1 1 9 10 10 10 7 Intra-flagellar transport protein 57 Mer2 PF09074.10 OWF41772.1 - 4.8e-10 39.6 0.0 29 4.4 0.0 7.9 5 3 3 8 8 8 0 Mer2 Vac_Fusion PF02346.16 OWF41772.1 - 1.6e-07 30.8 14.1 1.6e+02 2.0 0.0 13.9 1 1 20 21 21 21 0 Chordopoxvirus multifunctional envelope protein A27 Laminin_II PF06009.12 OWF41772.1 - 2e-07 31.1 0.0 17 5.4 0.0 6.4 1 1 9 10 10 10 0 Laminin Domain II TRPM_tetra PF16519.5 OWF41772.1 - 0.03 14.4 0.2 47 4.2 0.0 6.2 2 1 3 8 8 8 0 Tetramerisation domain of TRPM HAP1_N PF04849.13 OWF41772.1 - 0.044 13.0 0.0 63 2.6 0.0 4.0 2 1 5 7 7 7 0 HAP1 N-terminal conserved region Tropomyosin PF00261.20 OWF41772.1 - 0.071 12.5 0.0 31 3.8 0.0 4.3 1 1 1 2 2 2 0 Tropomyosin MscS_porin PF12795.7 OWF41772.1 - 0.17 11.4 0.0 1.4e+02 1.9 0.0 4.5 4 2 2 6 6 6 0 Mechanosensitive ion channel porin domain MetOD2 PF18548.1 OWF41772.1 - 1.5 9.0 60.7 67 3.7 0.6 15.1 1 1 5 6 6 5 0 Metanogen output domain 2 DUF4303 PF14136.6 OWF41772.1 - 3.6 7.3 70.9 21 4.8 1.0 13.1 1 1 10 11 11 11 0 Domain of unknown function (DUF4303) Gal_Lectin PF02140.18 OWF41773.1 - 2.7e-71 236.0 33.5 4.6e-25 87.8 5.6 3.9 4 0 0 4 4 4 3 Galactose binding lectin domain DUF3395 PF11875.8 OWF41773.1 - 0.18 11.7 7.3 13 5.6 0.2 4.7 4 2 1 5 5 5 0 Domain of unknown function (DUF3395) Neur_chan_LBD PF02931.23 OWF41774.1 - 1.7e-43 148.6 1.4 2.2e-43 148.2 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41774.1 - 6.5e-29 101.7 5.8 1.5e-25 90.7 3.7 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Bcl-2 PF00452.19 OWF41775.1 - 1.7e-22 79.9 0.1 5.1e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family bcl-2I13 PF12201.8 OWF41775.1 - 0.24 11.3 0.1 1 9.3 0.0 1.8 2 0 0 2 2 2 0 Bcl2-interacting killer, BH3-domain containing Pep3_Vps18 PF05131.14 OWF41777.1 - 1.7e-43 148.0 0.0 7e-43 146.0 0.0 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OWF41777.1 - 4.6e-09 36.3 5.3 4.6e-09 36.3 5.3 3.6 3 1 1 4 4 3 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 OWF41777.1 - 0.0051 16.7 0.6 0.013 15.5 0.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.9 OWF41777.1 - 0.016 15.6 0.0 0.051 14.0 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 OWF41777.1 - 0.017 15.0 1.2 0.017 15.0 1.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PspA_IM30 PF04012.12 OWF41777.1 - 0.023 14.3 2.2 0.52 9.9 0.2 2.7 2 0 0 2 2 2 0 PspA/IM30 family zf-RING_11 PF17123.5 OWF41777.1 - 0.027 14.2 1.0 0.027 14.2 1.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 OWF41777.1 - 0.056 13.8 0.5 0.21 11.9 0.5 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 OWF41777.1 - 0.11 12.6 1.2 0.26 11.3 1.2 1.7 1 0 0 1 1 1 0 Zinc-finger COMP PF11598.8 OWF41777.1 - 0.13 12.7 1.8 3.2 8.3 0.2 3.2 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein Zn_ribbon_17 PF17120.5 OWF41777.1 - 0.17 11.6 3.1 0.068 12.8 0.5 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OWF41777.1 - 0.19 11.8 0.8 0.61 10.1 0.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF41777.1 - 0.67 9.9 2.4 0.79 9.7 0.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 OWF41777.1 - 1.9 8.5 8.4 4.7 7.2 0.3 4.6 5 2 1 6 6 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OWF41777.1 - 5 7.6 8.1 8.3 6.9 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat YcaO PF02624.16 OWF41778.1 - 0.22 10.7 0.8 0.86 8.8 0.1 1.9 2 0 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding DUF2847 PF11009.8 OWF41778.1 - 2.2 8.3 18.5 10 6.1 0.1 6.9 6 1 3 9 9 9 0 Protein of unknown function (DUF2847) MAM PF00629.23 OWF41779.1 - 0 9511.8 246.6 2.5e-49 167.2 0.7 69.1 69 0 0 69 69 69 69 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 OWF41779.1 - 7.5e-126 410.0 359.2 9.8e-09 35.3 15.7 21.9 21 0 0 21 21 21 21 Low-density lipoprotein receptor domain class A SKG6 PF08693.10 OWF41779.1 - 6.9e-05 22.2 0.3 0.00019 20.7 0.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain IgGFc_binding PF17517.2 OWF41780.1 - 3.1e-40 138.3 5.0 3.1e-40 138.3 5.0 1.6 2 0 0 2 2 2 1 IgGFc binding protein Ldl_recept_a PF00057.18 OWF41782.1 - 0.0053 16.9 27.4 7.1 6.9 0.4 5.6 1 1 4 5 5 5 5 Low-density lipoprotein receptor domain class A DAP_B PF07930.12 OWF41782.1 - 0.0088 16.0 1.3 4.7 7.1 0.1 2.7 1 1 2 3 3 3 3 D-aminopeptidase, domain B LRRNT PF01462.18 OWF41782.1 - 0.064 12.9 29.6 7.4 6.3 0.5 5.8 4 2 2 6 6 6 0 Leucine rich repeat N-terminal domain Ribosomal_L31 PF01197.18 OWF41782.1 - 1.1 9.5 7.6 17 5.7 7.6 2.2 1 1 0 1 1 1 0 Ribosomal protein L31 I-set PF07679.16 OWF41783.1 - 1.8e-50 169.0 10.4 2e-11 43.8 0.1 5.2 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF41783.1 - 2.7e-49 165.6 34.9 2.4e-12 47.3 2.1 5.2 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 OWF41783.1 - 7.8e-41 138.1 32.2 1.6e-09 37.8 2.9 5.2 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 OWF41783.1 - 2.6e-31 107.8 30.9 1.2e-08 35.1 1.2 5.3 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 OWF41783.1 - 9.3e-29 99.8 31.4 1.3e-05 25.3 0.9 9.3 5 5 0 5 5 5 5 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 OWF41783.1 - 3.4e-09 36.6 11.7 0.017 15.2 0.2 5.6 5 0 0 5 5 5 3 C17orf99 Ig domain Ig_5 PF16681.5 OWF41783.1 - 4.9e-09 36.5 0.6 0.49 10.8 0.0 5.9 5 2 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF41783.1 - 1.7e-08 33.9 1.2 0.29 10.8 0.0 4.7 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 OWF41783.1 - 2.1e-06 27.7 0.1 6.2 6.9 0.0 5.3 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 OWF41783.1 - 5.5e-06 26.6 1.4 0.84 9.9 0.2 6.1 5 2 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 OWF41783.1 - 1e-05 25.6 7.6 1.8 8.8 0.1 5.2 4 1 1 5 5 5 2 Natural killer cell receptor 2B4 C2-set PF05790.15 OWF41783.1 - 0.00066 19.8 5.1 36 4.6 0.0 6.3 7 0 0 7 7 6 0 Immunoglobulin C2-set domain C2-set_2 PF08205.12 OWF41783.1 - 0.027 14.6 0.4 0.027 14.6 0.4 3.1 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 OWF41783.1 - 0.13 12.7 7.9 3.7 8.0 0.1 4.4 5 0 0 5 5 5 0 Immunoglobulin C1-set domain LRR_8 PF13855.6 OWF41784.1 - 3.3e-16 58.8 22.4 6.2e-06 25.9 0.1 6.1 2 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 OWF41784.1 - 1e-06 28.9 29.9 0.0098 16.3 0.1 7.0 4 3 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF41784.1 - 0.00019 21.4 7.8 0.027 14.4 0.1 3.4 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 OWF41784.1 - 0.0015 18.1 5.2 0.0015 18.1 5.2 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 OWF41784.1 - 0.0018 18.5 6.1 14 6.7 0.0 6.8 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_9 PF14580.6 OWF41784.1 - 0.21 11.1 10.6 0.6 9.6 0.9 3.0 2 1 0 3 3 3 0 Leucine-rich repeat LRR_8 PF13855.6 OWF41785.1 - 4.9e-27 93.5 7.3 3.1e-05 23.6 0.0 6.7 4 2 4 8 8 8 7 Leucine rich repeat LRR_5 PF13306.6 OWF41785.1 - 1.6e-07 31.3 3.8 0.17 11.8 2.3 3.6 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF41785.1 - 4.3e-07 30.2 17.6 0.028 14.9 0.5 7.0 6 1 4 10 10 10 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF41785.1 - 5.3e-05 22.8 0.6 0.046 13.2 0.1 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 OWF41786.1 - 2.9e-29 100.6 4.3 2.1e-06 27.4 0.1 7.1 4 2 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 OWF41786.1 - 5.3e-11 42.6 13.1 0.15 12.5 0.2 6.7 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF41786.1 - 9.9e-09 35.2 1.4 0.057 13.4 0.2 4.0 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF41786.1 - 0.00026 20.5 1.5 1.3 8.5 0.0 3.4 2 1 0 2 2 2 2 Leucine-rich repeat PARP PF00644.20 OWF41787.1 - 7.4e-27 94.2 0.9 7.5e-21 74.6 0.1 3.3 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain IBR PF01485.21 OWF41787.1 - 1.8e-05 24.9 5.6 1.8e-05 24.9 5.6 4.0 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Zn_Tnp_IS91 PF14319.6 OWF41787.1 - 0.39 10.8 16.1 0.11 12.5 6.0 2.9 2 0 0 2 2 2 0 Transposase zinc-binding domain SPT2 PF08243.11 OWF41788.1 - 9.9e-20 71.1 20.6 9.9e-20 71.1 20.6 10.3 6 3 4 10 10 10 2 SPT2 chromatin protein MMS1_N PF10433.9 OWF41789.1 - 8.1e-117 390.8 0.2 1.7e-116 389.8 0.1 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OWF41789.1 - 2.2e-83 280.2 0.1 3.3e-82 276.4 0.1 2.4 2 0 0 2 2 2 1 CPSF A subunit region Ku_N PF03731.15 OWF41790.1 - 4.4e-53 180.3 3.7 7.3e-53 179.6 3.7 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 OWF41790.1 - 3.9e-52 176.9 0.0 7e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 OWF41790.1 - 1.5e-22 80.1 0.3 1.5e-22 80.1 0.3 3.3 4 0 0 4 4 4 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 OWF41790.1 - 3.5e-06 27.4 0.0 1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain SAP PF02037.27 OWF41790.1 - 2.3e-05 24.0 0.1 6.5e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 OWF41790.1 - 0.018 15.7 0.0 0.14 12.8 0.0 2.3 1 1 0 1 1 1 0 von Willebrand factor type A domain Fibrinogen_C PF00147.18 OWF41791.1 - 2.3e-36 125.7 0.1 2.8e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF41792.1 - 3.9e-55 187.1 4.5 5e-55 186.7 4.5 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DSPc PF00782.20 OWF41793.1 - 1.2e-30 106.1 0.1 1.5e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF41793.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF41793.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-met PF12874.7 OWF41794.1 - 7.2e-44 147.0 70.7 3.2e-06 27.3 0.5 11.7 11 0 0 11 11 11 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF41794.1 - 3.1e-37 126.1 65.8 4.9e-06 26.7 0.2 11.7 11 0 0 11 11 11 10 Zinc-finger double-stranded RNA-binding Helicase_C PF00271.31 OWF41794.1 - 1.6e-15 57.4 0.1 8.4e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C2H2_2 PF12756.7 OWF41794.1 - 1.4e-12 47.8 72.1 0.12 12.7 0.4 11.9 8 3 4 12 12 12 11 C2H2 type zinc-finger (2 copies) ResIII PF04851.15 OWF41794.1 - 1.5e-11 44.6 0.0 4.7e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF41794.1 - 2.2e-09 37.3 0.0 1.1e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ribosomal_L24 PF17136.4 OWF41794.1 - 0.23 11.9 1.7 7.7 7.0 0.1 3.5 3 0 0 3 3 3 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 zf-ANAPC11 PF12861.7 OWF41794.1 - 4.4 7.4 6.6 14 5.8 0.0 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger Neur_chan_LBD PF02931.23 OWF41795.1 - 6.2e-44 150.0 0.1 8.4e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41795.1 - 2.7e-07 30.9 0.0 4.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SK_channel PF03530.14 OWF41795.1 - 0.16 12.0 0.9 9.9 6.2 0.0 2.9 3 0 0 3 3 3 0 Calcium-activated SK potassium channel 7tm_1 PF00001.21 OWF41796.1 - 3.8e-11 42.8 20.6 6.5e-11 42.0 20.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1772 PF08592.11 OWF41796.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Yip1 PF04893.17 OWF41796.1 - 4.1 7.1 18.2 0.065 12.9 6.2 2.6 1 1 1 2 2 2 0 Yip1 domain FAM47 PF14642.6 OWF41797.1 - 0.042 13.4 0.8 14 5.2 0.0 4.8 1 1 0 1 1 1 0 FAM47 family Ank_2 PF12796.7 OWF41798.1 - 1.9e-23 82.8 0.3 2.4e-18 66.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF41798.1 - 1.4e-19 69.9 1.6 7.4e-10 38.9 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF41798.1 - 1.1e-18 65.4 0.1 8.3e-06 25.8 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OWF41798.1 - 6.2e-18 64.4 3.6 1.1e-06 28.8 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OWF41798.1 - 2.4e-17 63.1 0.2 1.1e-08 35.4 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 OWF41798.1 - 0.17 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Shigella flexneri OspC protein TIR PF01582.20 OWF41799.1 - 0.00031 20.6 0.1 0.00035 20.4 0.1 1.1 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF41799.1 - 0.0089 16.6 0.0 0.017 15.7 0.0 1.5 1 1 0 1 1 1 1 TIR domain RNB PF00773.19 OWF41800.1 - 2.9e-94 316.1 0.0 5.3e-94 315.2 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OWF41800.1 - 7.3e-20 70.8 0.0 2.2e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 OWF41800.1 - 9.1e-15 54.7 0.0 2.3e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 OWF41800.1 - 2.1e-14 54.0 0.3 5.7e-14 52.5 0.3 1.8 1 0 0 1 1 1 1 PIN domain Rrp44_S1 PF17215.3 OWF41800.1 - 2.7e-08 33.6 0.0 6.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 OWF41800.1 - 4.1e-08 33.3 1.9 1.4e-07 31.5 0.1 2.7 3 0 0 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 OWF41800.1 - 0.016 15.5 0.0 0.053 13.9 0.0 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal VWA PF00092.28 OWF41801.1 - 1.6e-79 266.2 2.8 1.6e-44 152.2 0.7 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWC PF00093.18 OWF41801.1 - 4.6e-29 100.5 717.5 0.0017 18.7 14.1 32.6 33 0 0 33 33 33 30 von Willebrand factor type C domain VWA_2 PF13519.6 OWF41801.1 - 4.2e-26 91.7 0.0 1.5e-17 64.1 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain ShK PF01549.24 OWF41801.1 - 2.4e-06 27.9 27.6 7.5e-05 23.2 12.3 14.7 16 0 0 16 16 16 6 ShK domain-like Trypan_PARP PF05887.11 OWF41801.1 - 0.0018 18.3 21.3 0.0018 18.3 21.3 15.2 16 0 0 16 16 16 4 Procyclic acidic repetitive protein (PARP) DUF1496 PF07383.12 OWF41801.1 - 2 8.1 50.4 1.8 8.2 0.3 14.2 17 0 0 17 17 17 0 Protein of unknown function (DUF1496) Pkinase PF00069.25 OWF41802.1 - 2.8e-73 246.5 0.0 5.5e-73 245.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41802.1 - 3.4e-42 144.5 0.0 5.4e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF41802.1 - 1.5e-09 37.6 0.0 1.9e-08 34.0 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 OWF41802.1 - 0.0054 16.1 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UNC-93 PF05978.16 OWF41803.1 - 9.9e-05 22.1 10.2 0.00033 20.4 9.5 2.3 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 TANGO2 PF05742.12 OWF41803.1 - 0.0041 17.2 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 Transport and Golgi organisation 2 zf-LITAF-like PF10601.9 OWF41803.1 - 0.18 12.1 0.3 0.18 12.1 0.3 3.6 4 1 1 5 5 5 0 LITAF-like zinc ribbon domain Cyt_c_ox_IV PF12270.8 OWF41803.1 - 0.71 10.0 9.7 0.5 10.5 5.5 2.9 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV UNC-93 PF05978.16 OWF41804.1 - 2.6e-06 27.2 1.8 2.6e-06 27.2 1.8 2.6 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 7tm_1 PF00001.21 OWF41805.1 - 3.6e-24 85.5 0.0 4.8e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.6 OWF41806.1 - 1.1e-51 171.1 93.0 8.1e-09 35.5 1.6 12.1 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 OWF41806.1 - 5.9e-38 127.2 99.4 8.3e-06 26.0 1.4 11.4 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF41806.1 - 7.9e-25 85.4 89.7 0.0018 18.9 0.8 11.5 11 0 0 11 11 11 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF41806.1 - 1.2e-21 76.2 77.6 1.1e-06 28.2 3.2 10.2 11 0 0 11 11 11 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 OWF41806.1 - 5.3e-05 23.4 0.7 5.3e-05 23.4 0.7 10.3 10 1 1 11 11 11 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF41806.1 - 0.00061 19.7 5.3 0.0055 16.7 0.3 9.4 10 0 0 10 10 10 3 C2H2-type zinc finger PriA_CRR PF18319.1 OWF41806.1 - 0.0016 18.4 0.3 0.0016 18.4 0.3 6.8 7 0 0 7 7 6 1 PriA DNA helicase Cys-rich region (CRR) domain GAGA PF09237.11 OWF41806.1 - 0.0045 16.8 17.5 0.28 11.0 0.1 5.7 4 2 2 6 6 5 3 GAGA factor zf-met PF12874.7 OWF41806.1 - 0.039 14.3 0.3 0.039 14.3 0.3 8.8 10 0 0 10 10 10 0 Zinc-finger of C2H2 type BolA PF01722.18 OWF41806.1 - 0.11 12.8 2.7 3.9 7.8 0.0 3.2 3 0 0 3 3 3 0 BolA-like protein Pyrid_oxidase_2 PF13883.6 OWF41806.1 - 0.25 11.3 1.6 4.5 7.2 0.2 2.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase zinc_ribbon_15 PF17032.5 OWF41806.1 - 0.59 10.9 41.0 2.8 8.7 1.9 6.1 1 1 3 7 7 7 0 zinc-ribbon family Carbam_trans_C PF16861.5 OWF41806.1 - 0.66 9.6 2.9 34 4.0 0.4 3.1 2 1 0 3 3 3 0 Carbamoyltransferase C-terminus zf_ZIC PF18366.1 OWF41806.1 - 0.69 10.1 11.2 2.5 8.3 0.2 3.9 3 1 1 4 4 4 0 Zic proteins zinc finger domain Fer4_13 PF13370.6 OWF41806.1 - 3 8.5 8.8 4.4 7.9 0.1 4.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I PRP1_N PF06424.12 OWF41806.1 - 3.3 8.1 9.0 11 6.4 9.0 2.0 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Zn-ribbon_8 PF09723.10 OWF41806.1 - 8.7 6.6 42.3 5.3 7.2 1.4 7.4 4 2 2 6 6 6 0 Zinc ribbon domain zf-C2H2 PF00096.26 OWF41808.1 - 3.8e-23 80.6 43.4 1.6e-06 28.2 1.4 6.9 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF41808.1 - 6.8e-20 70.1 44.7 0.00017 22.2 1.1 7.0 7 0 0 7 7 6 6 C2H2-type zinc finger zf-met PF12874.7 OWF41808.1 - 7.7e-12 45.2 24.7 0.018 15.4 0.2 6.6 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OWF41808.1 - 2.4e-08 34.0 50.8 2.9e-07 30.6 0.7 8.0 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF41808.1 - 8.7e-08 32.3 31.9 0.0018 18.5 1.3 6.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF41808.1 - 0.00045 20.2 26.1 0.074 13.1 0.2 6.1 6 0 0 6 6 6 2 C2H2-type zinc finger DUF4764 PF15961.5 OWF41808.1 - 0.0016 17.2 5.4 0.0016 17.2 5.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4764) FOXP-CC PF16159.5 OWF41808.1 - 0.013 16.1 19.2 0.39 11.4 0.2 5.3 4 1 1 5 5 5 0 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 OWF41808.1 - 0.036 14.7 22.5 1.5 9.5 0.4 5.2 2 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 OWF41808.1 - 0.069 13.5 31.1 0.086 13.1 1.6 5.3 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 OWF41808.1 - 0.85 10.0 21.5 0.43 10.9 5.3 4.1 3 2 1 4 4 4 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 OWF41808.1 - 3.1 8.3 27.0 1.6 9.2 2.1 5.2 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 OWF41808.1 - 3.3 7.6 21.4 0.19 11.5 0.4 4.6 4 1 0 4 4 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OWF41808.1 - 4.2 7.7 36.7 1.7 9.0 0.7 6.2 4 1 1 5 5 4 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.14 OWF41808.1 - 6.7 6.7 17.5 13 5.8 0.6 4.3 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.6 OWF41809.1 - 1e-25 88.2 61.9 0.0071 17.1 1.1 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF41809.1 - 6.4e-25 86.2 70.6 0.00063 20.1 0.1 10.7 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF41809.1 - 1.6e-06 28.3 72.1 0.036 14.5 0.7 10.7 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2_8 PF15909.5 OWF41809.1 - 3.7e-05 23.9 32.2 0.0073 16.6 4.6 4.8 2 2 2 4 4 4 3 C2H2-type zinc ribbon zf-Di19 PF05605.12 OWF41809.1 - 5.9e-05 23.3 45.5 0.21 11.9 1.8 6.6 4 3 3 7 7 7 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OWF41809.1 - 7.2e-05 23.0 47.9 0.024 14.9 1.5 9.7 11 0 0 11 11 11 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF41809.1 - 0.0003 20.7 56.7 0.01 15.8 0.3 9.3 8 2 0 8 8 8 3 C2H2-type zinc finger zf-met PF12874.7 OWF41809.1 - 0.029 14.8 41.1 4.9 7.7 0.1 9.5 10 0 0 10 10 10 0 Zinc-finger of C2H2 type GAGA PF09237.11 OWF41809.1 - 1 9.2 5.1 3.6 7.5 0.1 3.9 4 1 1 5 5 5 0 GAGA factor Ly49 PF08391.10 OWF41810.1 - 0.025 14.9 0.3 0.025 14.9 0.3 2.5 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Acid_PPase PF12689.7 OWF41811.1 - 1.3e-39 135.7 0.0 2.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 OWF41811.1 - 8.8e-07 29.2 2.6 2.9e-06 27.5 0.0 2.4 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 OWF41811.1 - 0.021 14.6 0.1 0.11 12.3 0.0 2.1 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase Hydrolase PF00702.26 OWF41811.1 - 0.026 14.8 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Neur_chan_LBD PF02931.23 OWF41812.1 - 2.1e-47 161.3 4.4 3.1e-47 160.8 4.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF41812.1 - 2.8e-08 34.1 3.6 6.1e-08 33.0 3.6 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Syndecan PF01034.20 OWF41813.1 - 0.00035 20.4 0.6 0.00074 19.4 0.6 1.5 1 0 0 1 1 1 1 Syndecan domain GPS PF01825.21 OWF41813.1 - 0.006 17.1 1.5 0.018 15.6 1.5 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif EphA2_TM PF14575.6 OWF41813.1 - 0.0072 17.2 0.2 0.021 15.7 0.2 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OWF41813.1 - 0.018 15.8 0.0 0.093 13.5 0.0 2.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Insulin_TMD PF17870.1 OWF41813.1 - 0.076 13.1 5.5 0.19 11.8 5.5 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 OWF41813.1 - 0.1 12.9 0.0 0.41 11.0 0.0 2.0 1 0 0 1 1 1 0 Orf78 (ac78) DUF2970 PF11174.8 OWF41813.1 - 0.34 10.8 3.4 0.7 9.8 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Ten1 PF12658.7 OWF41814.1 - 0.12 12.3 0.3 0.77 9.7 0.1 2.3 3 0 0 3 3 3 0 Telomere capping, CST complex subunit SNF PF00209.18 OWF41815.1 - 1.8e-123 413.0 36.0 2.6e-123 412.5 36.0 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 4HBT_2 PF13279.6 OWF41815.1 - 0.055 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Thioesterase-like superfamily TMEM132D_C PF15706.5 OWF41816.1 - 0.0028 17.4 0.0 0.0089 15.8 0.0 1.8 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TrbL PF04610.14 OWF41816.1 - 0.0033 17.2 0.4 0.0077 16.0 0.4 1.6 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Cytadhesin_P30 PF07271.11 OWF41816.1 - 0.016 14.8 8.3 0.016 14.8 8.3 3.5 2 1 2 4 4 4 0 Cytadhesin P30/P32 EphA2_TM PF14575.6 OWF41816.1 - 0.03 15.2 0.0 0.11 13.3 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OWF41816.1 - 0.037 14.3 0.4 0.27 11.6 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) MPS-4 PF17523.2 OWF41816.1 - 0.92 9.7 3.3 29 4.9 0.3 3.5 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Mab-21 PF03281.14 OWF41817.1 - 6.1e-16 58.6 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Mab-21 protein S6PP PF05116.13 OWF41817.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Baculo_PP31 PF05311.11 OWF41818.1 - 0.026 14.0 0.9 0.035 13.6 0.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Trypsin PF00089.26 OWF41818.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Trypsin Trypsin_2 PF13365.6 OWF41819.1 - 2e-10 41.8 0.0 3.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF41819.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Trypsin Trypsin_2 PF13365.6 OWF41820.1 - 4.3e-09 37.4 0.0 7.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF41820.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Trypsin 7TM_GPCR_Srw PF10324.9 OWF41821.1 - 1.7e-24 86.7 17.6 4.3e-24 85.4 17.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF41821.1 - 5.1e-24 85.0 14.3 6.4e-24 84.7 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 OWF41821.1 - 9.4e-06 24.9 14.5 3.9e-05 22.9 14.4 1.9 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7TM_GPCR_Srw PF10324.9 OWF41822.1 - 9.2e-22 77.7 23.6 1.3e-21 77.3 23.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF41822.1 - 1.7e-14 53.8 21.0 2.5e-14 53.2 21.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF41822.1 - 7.6e-07 28.8 23.9 3e-06 26.8 23.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF41822.1 - 0.00023 20.9 13.3 0.00023 20.9 13.3 3.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 OWF41822.1 - 0.00028 20.7 4.8 0.00028 20.7 4.8 3.1 1 1 1 3 3 3 1 Srg family chemoreceptor Ank_2 PF12796.7 OWF41823.1 - 2.6e-21 76.0 0.1 8.9e-10 39.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF41823.1 - 1.2e-18 67.2 0.2 4.5e-05 23.9 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF41823.1 - 6.2e-17 61.2 0.0 0.00016 22.0 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 OWF41823.1 - 6.6e-17 61.7 0.0 1.7e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OWF41823.1 - 7.8e-17 61.1 0.5 1.7e-05 25.0 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OWF41823.1 - 4.1e-13 49.2 0.0 7.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 OWF41823.1 - 6.6e-13 48.9 0.1 4.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease 2-5A Ank_3 PF13606.6 OWF41823.1 - 8e-11 41.2 0.0 0.023 15.2 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat PEHE PF15275.6 OWF41823.1 - 3.8 8.1 7.8 2.2 8.9 4.2 2.6 2 0 0 2 2 2 0 PEHE domain DUF3361 PF11841.8 OWF41824.1 - 1.9e-42 144.8 0.7 3.9e-42 143.8 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 OWF41824.1 - 3.1e-37 128.4 0.0 6.9e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 OWF41824.1 - 3.9e-30 105.1 0.0 1e-29 103.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Aminotran_1_2 PF00155.21 OWF41825.1 - 8.4e-88 295.0 0.0 9.8e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II 60KD_IMP PF02096.20 OWF41826.1 - 2.2e-26 92.8 5.4 2.2e-26 92.8 5.4 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein Sm_multidrug_ex PF06695.11 OWF41826.1 - 0.011 16.4 0.3 0.048 14.3 0.1 2.1 2 0 0 2 2 2 0 Putative small multi-drug export protein OSTbeta PF15048.6 OWF41826.1 - 0.043 14.0 0.8 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein F-box-like PF12937.7 OWF41827.1 - 1.9e-11 43.7 4.1 9.9e-10 38.2 2.1 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 OWF41827.1 - 2.4e-11 43.2 1.0 2e-09 37.1 0.2 2.7 2 0 0 2 2 2 2 F-box domain F-box_5 PF18511.1 OWF41827.1 - 0.0026 17.3 0.0 0.0073 15.9 0.0 1.8 1 0 0 1 1 1 1 F-box tRNA-synt_2c PF01411.19 OWF41828.1 - 1.7e-220 733.2 0.0 2.6e-220 732.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 OWF41828.1 - 1.8e-15 57.6 0.3 4.7e-15 56.2 0.3 1.8 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 OWF41828.1 - 3.8e-15 55.7 0.1 8.7e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HTH_WhiA PF02650.14 OWF41828.1 - 0.046 14.0 0.8 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 WhiA C-terminal HTH domain E1-E2_ATPase PF00122.20 OWF41829.1 - 3.7e-52 176.5 0.0 1.5e-51 174.5 0.0 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OWF41829.1 - 3.6e-44 150.6 6.6 7.7e-44 149.6 6.6 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 OWF41829.1 - 4e-18 64.9 0.0 9.5e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 OWF41829.1 - 2.8e-15 57.2 0.1 3.9e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OWF41829.1 - 5.8e-15 55.1 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Saf_2TM PF18303.1 OWF41829.1 - 0.054 13.1 3.2 1.4 8.5 0.1 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF1634 PF07843.11 OWF41829.1 - 0.47 10.6 4.9 0.38 10.9 1.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) 7TM-7TMR_HD PF07698.11 OWF41829.1 - 1.9 8.2 9.9 0.57 9.9 5.2 2.4 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase adh_short PF00106.25 OWF41830.1 - 1.2e-40 139.1 7.7 3.6e-35 121.2 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF41830.1 - 9.7e-34 116.9 3.4 1.1e-29 103.7 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF41830.1 - 1.8e-07 31.3 4.3 1.5e-06 28.2 0.1 2.6 3 0 0 3 3 3 1 KR domain THF_DHG_CYH_C PF02882.19 OWF41830.1 - 3.2e-05 23.3 0.9 0.14 11.5 0.1 2.4 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 OWF41830.1 - 0.0007 19.7 14.1 0.064 13.3 4.3 2.4 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.21 OWF41830.1 - 0.57 9.6 4.1 0.75 9.2 0.1 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Ribonuc_P_40 PF08584.11 OWF41831.1 - 3.3e-57 193.9 0.0 4.7e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit PH PF00169.29 OWF41832.1 - 2.7e-09 37.5 0.1 5e-09 36.6 0.1 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF41832.1 - 0.12 12.8 2.0 0.47 10.9 2.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Ion_trans PF00520.31 OWF41834.1 - 2.6e-20 72.7 13.6 3.8e-20 72.2 13.6 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OWF41834.1 - 7.8e-17 61.1 0.0 1.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OWF41834.1 - 0.38 10.7 4.8 0.89 9.6 4.8 1.7 1 0 0 1 1 1 0 Ion channel Iwr1 PF08574.10 OWF41835.1 - 3.3e-09 37.6 15.6 3.3e-09 37.6 15.6 4.0 4 2 0 4 4 4 1 Transcription factor Iwr1 Imm5 PF14423.6 OWF41835.1 - 4.4 7.5 7.5 2.6 8.2 0.8 2.3 2 0 0 2 2 2 0 Immunity protein Imm5 60KD_IMP PF02096.20 OWF41836.1 - 5.4e-25 88.2 0.9 9.3e-25 87.4 0.9 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Hexapep PF00132.24 OWF41837.1 - 0.29 10.9 55.5 13 5.7 0.8 12.5 1 1 12 13 13 13 0 Bacterial transferase hexapeptide (six repeats) RPT PF13446.6 OWF41838.1 - 0.0029 17.5 3.4 44 4.1 0.2 5.4 3 2 2 5 5 5 1 A repeated domain in UCH-protein tRNA-synt_His PF13393.6 OWF41838.1 - 0.0034 16.7 0.3 20 4.3 0.0 3.7 3 1 1 4 4 4 2 Histidyl-tRNA synthetase DUF2999 PF11212.8 OWF41838.1 - 0.08 13.2 0.1 28 5.1 0.1 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2999) zf-C2H2 PF00096.26 OWF41839.1 - 1.2e-11 44.4 17.1 4e-05 23.8 3.0 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF41839.1 - 3.2e-10 40.0 17.7 0.0012 19.5 0.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF41839.1 - 3.7e-06 27.1 19.5 0.00053 20.3 0.1 4.5 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF41839.1 - 1.5e-05 25.1 11.3 0.0015 18.8 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF41839.1 - 1.6e-05 24.7 12.6 0.0007 19.5 0.2 3.7 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OWF41839.1 - 2.7e-05 23.9 12.1 0.033 14.1 0.7 3.3 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-Di19 PF05605.12 OWF41839.1 - 0.00035 20.8 1.0 0.00035 20.8 1.0 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-MIZ PF02891.20 OWF41839.1 - 0.002 17.8 3.6 0.42 10.4 0.8 2.5 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger zf-met PF12874.7 OWF41839.1 - 0.0032 17.8 9.4 0.34 11.4 0.6 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 OWF41839.1 - 0.0045 16.7 1.8 0.0045 16.7 1.8 3.2 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.15 OWF41839.1 - 0.0094 16.0 3.3 1.2 9.2 0.2 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Zn_Tnp_IS1595 PF12760.7 OWF41839.1 - 0.011 15.7 3.4 0.021 14.8 3.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rep_fac-A_C PF08646.10 OWF41839.1 - 0.065 13.0 5.1 2.4 7.9 0.3 2.4 1 1 1 2 2 2 0 Replication factor-A C terminal domain zf-MYST PF17772.1 OWF41839.1 - 0.08 12.6 2.1 2.9 7.6 0.3 2.4 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_9 PF16293.5 OWF41839.1 - 0.086 12.7 0.6 0.82 9.6 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 OWF41839.1 - 0.1 13.0 10.3 0.9 9.9 2.0 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-RanBP PF00641.18 OWF41839.1 - 0.1 11.9 9.9 1.6 8.1 2.9 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C2H2_8 PF15909.5 OWF41839.1 - 0.1 12.9 2.5 0.26 11.6 1.9 1.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon BolA PF01722.18 OWF41839.1 - 0.11 12.7 1.3 0.18 12.1 0.5 1.9 2 1 0 2 2 1 0 BolA-like protein Zn_ribbon_SprT PF17283.2 OWF41839.1 - 0.13 12.2 7.5 0.087 12.7 2.7 2.7 2 1 1 3 3 3 0 SprT-like zinc ribbon domain DUF2225 PF09986.9 OWF41839.1 - 0.16 11.6 4.8 2.8 7.6 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) C1_2 PF03107.16 OWF41839.1 - 0.2 12.0 0.6 0.2 12.0 0.6 2.7 2 1 1 3 3 2 0 C1 domain zf_UBZ PF18439.1 OWF41839.1 - 0.21 11.2 5.0 2.3 7.9 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 OWF41839.1 - 0.39 10.8 13.9 0.32 11.0 1.1 3.2 2 1 1 3 3 3 0 BED zinc finger DUF2175 PF09943.9 OWF41839.1 - 0.6 10.4 4.2 1.3 9.3 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) PHD PF00628.29 OWF41839.1 - 0.62 10.0 9.3 0.3 11.0 0.7 2.7 3 0 0 3 3 2 0 PHD-finger ADK_lid PF05191.14 OWF41839.1 - 0.73 9.9 6.8 1 9.4 4.0 2.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid Rad50_zn_hook PF04423.14 OWF41839.1 - 2 8.3 6.2 3.1 7.7 0.4 2.9 2 1 1 3 3 3 0 Rad50 zinc hook motif DUF4379 PF14311.6 OWF41839.1 - 2.2 8.7 10.5 22 5.5 1.5 2.6 1 1 1 2 2 2 0 Probable Zinc-ribbon domain SCAN PF02023.17 OWF41840.1 - 0.7 9.8 2.7 16 5.3 0.1 2.7 1 1 2 3 3 3 0 SCAN domain IL5 PF02025.15 OWF41840.1 - 0.88 9.9 9.3 18 5.6 0.1 3.0 1 1 1 2 2 2 0 Interleukin 5 Orn_Arg_deC_N PF02784.16 OWF41841.1 - 3.6e-38 131.4 0.0 1.1e-36 126.5 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF41841.1 - 7.4e-22 77.4 0.0 1.4e-21 76.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 OWF41841.1 - 3.8e-06 26.7 0.0 5.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain GDA1_CD39 PF01150.17 OWF41842.1 - 1.2e-59 202.1 0.0 1.8e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OWF41842.1 - 0.037 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF4515 PF14988.6 OWF41843.1 - 1.8e-19 70.4 41.9 1.8e-19 70.4 41.9 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4515) MHB PF16525.5 OWF41843.1 - 6.6 7.1 6.2 61 4.0 0.3 3.7 3 0 0 3 3 3 0 Haemophore, haem-binding HILPDA PF15220.6 OWF41844.1 - 1.4 9.1 12.2 16 5.7 3.2 3.4 1 1 2 3 3 3 0 Hypoxia-inducible lipid droplet-associated Nucleoside_tran PF01733.18 OWF41845.1 - 1.7e-71 241.2 16.4 1.7e-71 241.2 16.4 2.2 1 1 1 2 2 2 2 Nucleoside transporter Utp12 PF04003.12 OWF41846.1 - 3.5e-19 69.1 0.6 8e-19 67.9 0.6 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 OWF41846.1 - 2.4e-07 31.3 11.9 2.8e-05 24.8 2.9 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF41846.1 - 3.5e-07 30.4 0.0 6e-05 23.3 0.0 3.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF41846.1 - 0.033 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain 2OG-FeII_Oxy_2 PF13532.6 OWF41846.1 - 0.091 12.9 0.0 2.9 8.0 0.0 2.5 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Astro_capsid_p PF12226.8 OWF41846.1 - 0.34 10.0 6.3 0.7 9.0 6.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sigma70_r1_1 PF03979.14 OWF41848.1 - 0.0066 16.5 0.1 0.009 16.0 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 Frizzled PF01534.17 OWF41849.1 - 7.4e-139 462.3 19.9 9.3e-139 462.0 19.9 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 OWF41849.1 - 2.2e-32 111.9 3.8 4.9e-32 110.9 3.8 1.5 1 0 0 1 1 1 1 Fz domain Mab-21 PF03281.14 OWF41853.1 - 6.4e-26 91.3 3.8 9e-26 90.8 3.8 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_7 PF13176.6 OWF41853.1 - 0.058 13.4 0.1 4.1 7.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF41853.1 - 0.19 12.1 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Med31 PF05669.12 OWF41854.1 - 0.0088 16.0 11.6 2 8.4 9.4 2.9 1 1 1 2 2 2 2 SOH1 Mid1 PF12929.7 OWF41855.1 - 1e-06 28.3 7.7 1e-06 28.3 7.7 2.9 2 1 1 3 3 3 2 Stretch-activated Ca2+-permeable channel component FYVE PF01363.21 OWF41856.1 - 9.6e-26 89.7 23.0 2e-15 56.7 5.2 2.6 2 0 0 2 2 2 2 FYVE zinc finger N-glycanase_N PF09112.10 OWF41856.1 - 0.00016 21.5 0.5 0.21 11.4 0.0 2.8 3 0 0 3 3 3 2 Peptide-N-glycosidase F, N terminal FYVE_2 PF02318.16 OWF41856.1 - 0.0039 17.4 2.4 0.0039 17.4 2.4 5.2 5 1 0 6 6 6 1 FYVE-type zinc finger DUF1492 PF07374.11 OWF41856.1 - 0.052 13.7 1.9 0.13 12.4 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) CorA PF01544.18 OWF41856.1 - 0.13 11.5 6.9 1.1 8.5 4.6 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 OWF41857.1 - 7.2e-32 110.8 23.7 8.7e-32 110.5 23.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF41857.1 - 1.1e-24 87.0 20.9 1.1e-24 87.0 20.9 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily tRNA-synt_1g PF09334.11 OWF41858.1 - 4.7e-105 351.5 0.1 6.4e-104 347.8 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OWF41858.1 - 1.8e-28 99.2 1.5 1.9e-12 46.2 1.2 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OWF41858.1 - 3.7e-14 52.8 0.0 2.6e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 OWF41858.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA rRNA_methylase PF06962.12 OWF41858.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase BAAT_C PF08840.11 OWF41859.1 - 6.5e-39 134.1 0.0 1.6e-38 132.8 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 OWF41859.1 - 6.4e-31 107.0 0.0 1.4e-30 105.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 OWF41859.1 - 0.00033 20.3 0.0 0.056 13.0 0.0 3.2 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF1758 PF05585.12 OWF41859.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Transglut_core PF01841.19 OWF41860.1 - 1.2e-20 74.0 0.0 2.1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 OWF41860.1 - 0.0015 18.1 0.3 0.025 14.1 0.3 2.5 1 1 0 1 1 1 1 Transglutaminase-like domain Filamin PF00630.19 OWF41860.1 - 0.016 16.1 0.1 0.26 12.2 0.0 2.7 2 2 0 2 2 2 0 Filamin/ABP280 repeat WD40 PF00400.32 OWF41861.1 - 5.5e-19 68.2 7.1 2.6e-06 28.1 0.2 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat FYVE PF01363.21 OWF41861.1 - 2.6e-14 53.1 8.1 2.6e-14 53.1 8.1 1.9 2 0 0 2 2 2 1 FYVE zinc finger ANAPC4_WD40 PF12894.7 OWF41861.1 - 0.0022 18.3 0.2 0.69 10.3 0.1 3.6 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Transglut_core PF01841.19 OWF41862.1 - 6.3e-21 74.9 0.1 1.1e-20 74.2 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 OWF41862.1 - 0.00075 19.1 0.6 0.021 14.4 0.6 2.6 1 1 0 1 1 1 1 Transglutaminase-like domain CCDC85 PF10226.9 OWF41862.1 - 0.0068 16.1 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 CCDC85 family Mab-21 PF03281.14 OWF41863.1 - 5.8e-27 94.8 0.6 8.8e-27 94.2 0.2 1.4 2 0 0 2 2 2 1 Mab-21 protein DUF3361 PF11841.8 OWF41863.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) UvrD_C_2 PF13538.6 OWF41864.1 - 0.0009 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 OWF41864.1 - 0.03 12.3 0.0 0.036 12.0 0.0 1.1 1 0 0 1 1 1 0 Helicase PIF1 PF05970.14 OWF41864.1 - 0.12 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase Kelch_1 PF01344.25 OWF41865.1 - 6.7e-82 268.9 22.0 1.9e-18 65.8 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF41865.1 - 4e-45 150.7 10.3 1.2e-08 34.9 0.0 6.4 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 OWF41865.1 - 9.1e-32 109.2 4.4 4e-31 107.2 2.2 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF41865.1 - 5.2e-28 97.5 3.8 1.6e-27 95.9 3.8 1.9 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 OWF41865.1 - 1.9e-23 81.5 15.5 0.00036 20.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OWF41865.1 - 4.9e-23 80.9 13.4 9.9e-08 31.9 0.0 6.2 4 1 2 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF41865.1 - 1.6e-20 72.9 14.9 4.5e-05 23.6 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF41865.1 - 0.0001 22.2 12.6 0.00096 19.1 0.0 4.7 6 0 0 6 6 5 2 Kelch motif DUF3342 PF11822.8 OWF41865.1 - 0.00056 20.1 3.4 0.0014 18.7 1.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 OWF41865.1 - 1 10.0 16.1 2.1 9.0 0.1 4.7 5 0 0 5 5 5 0 PQQ-like domain DUF4441 PF14536.6 OWF41865.1 - 6.3 7.0 8.6 0.5 10.6 2.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) MIEAP PF16026.5 OWF41866.1 - 1.9e-28 100.1 1.8 1.9e-28 100.1 1.8 1.9 2 0 0 2 2 2 1 Mitochondria-eating protein APO_RNA-bind PF05634.11 OWF41866.1 - 0.04 13.3 0.8 0.081 12.3 0.8 1.4 1 0 0 1 1 1 0 APO RNA-binding HSP70 PF00012.20 OWF41867.1 - 0.00049 18.4 0.0 0.0023 16.2 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF41867.1 - 0.061 12.1 0.5 2.3 6.9 0.0 2.5 3 0 0 3 3 3 0 MreB/Mbl protein Pam16 PF03656.13 OWF41868.1 - 5.9e-42 142.7 0.5 7e-42 142.4 0.5 1.0 1 0 0 1 1 1 1 Pam16 Polysacc_deac_1 PF01522.21 OWF41869.1 - 9.5e-08 32.0 0.1 2.9e-07 30.4 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Tnp_DNA_bind PF14706.6 OWF41871.1 - 1.2e-05 25.1 16.9 14 5.7 0.1 9.8 3 2 9 15 15 15 2 Transposase DNA-binding DUF1938 PF09153.10 OWF41871.1 - 9.2e-05 22.5 0.0 45 4.2 0.0 6.6 1 1 4 8 8 8 0 Domain of unknown function (DUF1938) Bd3614-deam PF14439.6 OWF41871.1 - 0.09 12.8 0.1 89 3.1 0.0 4.3 1 1 1 3 3 3 0 Bd3614-like deaminase DUF1082 PF06449.11 OWF41871.1 - 6.3 6.7 24.1 45 4.0 0.2 8.2 1 1 9 12 12 12 0 Mitochondrial domain of unknown function (DUF1082) Folliculin PF11704.8 OWF41871.1 - 6.3 6.6 27.2 48 3.8 0.1 10.2 1 1 11 12 12 12 0 Vesicle coat protein involved in Golgi to plasma membrane transport UQ_con PF00179.26 OWF41872.1 - 9.1e-20 70.7 0.0 1.8e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF41872.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B Spore_YunB PF09560.10 OWF41872.1 - 0.28 11.2 4.0 0.071 13.1 0.6 1.9 2 0 0 2 2 2 0 Sporulation protein YunB (Spo_YunB) zf-MYND PF01753.18 OWF41873.1 - 8.2e-12 45.0 12.7 1.6e-11 44.1 12.7 1.5 1 0 0 1 1 1 1 MYND finger ubiquitin PF00240.23 OWF41873.1 - 0.0023 17.7 0.1 0.011 15.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family Ecl1 PF12855.7 OWF41873.1 - 0.057 14.6 5.2 0.078 14.1 5.2 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins EutC PF05985.11 OWF41873.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) zf-C6H2 PF15801.5 OWF41873.1 - 1.1 9.6 6.8 3 8.2 6.8 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding cNMP_binding PF00027.29 OWF41874.1 - 1.4e-20 73.1 0.0 2.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OWF41874.1 - 3.5e-16 59.2 20.9 5.1e-16 58.7 20.9 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 OWF41874.1 - 7.3e-07 29.5 5.3 2e-06 28.1 5.3 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ion_trans_2 PF07885.16 OWF41874.1 - 0.00011 22.1 6.3 0.00011 22.1 6.3 2.2 2 0 0 2 2 2 1 Ion channel RP-C_C PF11800.8 OWF41874.1 - 0.042 13.9 5.2 0.067 13.3 5.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4400 PF14348.6 OWF41874.1 - 0.5 9.8 4.0 1.2 8.6 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4400) CAP_GLY PF01302.25 OWF41875.1 - 6.7e-21 74.1 0.8 1.3e-20 73.1 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF4192 PF13830.6 OWF41875.1 - 7.2 6.6 7.7 0.68 9.9 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Rick_17kDa_Anti PF05433.15 OWF41876.1 - 1e-05 25.3 34.0 2.9e+02 1.4 0.0 17.2 19 0 0 19 19 19 0 Glycine zipper 2TM domain Cadherin_3 PF16184.5 OWF41877.1 - 1.3e-241 785.0 37.5 1.5e-25 89.4 0.3 13.4 12 0 0 12 12 12 12 Cadherin-like Calx-beta PF03160.14 OWF41877.1 - 2.2e-71 236.3 12.2 6.9e-16 58.3 0.7 6.8 6 1 0 6 6 6 5 Calx-beta domain Big_9 PF17963.1 OWF41877.1 - 2.5e-11 44.1 31.8 0.015 16.0 2.2 10.2 9 0 0 9 9 9 5 Bacterial Ig domain Cadherin_4 PF17803.1 OWF41877.1 - 9.3e-05 23.0 23.3 0.091 13.4 3.2 7.3 6 0 0 6 6 6 3 Bacterial cadherin-like domain DUF3889 PF13028.6 OWF41877.1 - 0.014 15.3 0.0 0.24 11.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3889) DUF4448 PF14610.6 OWF41877.1 - 0.079 12.7 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) CAF1 PF04857.20 OWF41879.1 - 1.1e-23 83.9 0.5 1.3e-11 44.3 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease Mod_r PF07200.13 OWF41880.1 - 1.4e-28 99.8 13.3 2.4e-28 99.1 13.3 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.26 OWF41880.1 - 0.00033 20.3 1.3 0.00097 18.8 1.3 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF41880.1 - 0.93 9.8 8.5 0.71 10.2 0.1 3.3 3 1 0 3 3 3 0 RWD domain zf-AN1 PF01428.16 OWF41881.1 - 1.6e-20 72.9 38.9 2.8e-11 43.4 13.7 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger UIM PF02809.20 OWF41881.1 - 3.1e-05 23.6 16.1 0.00022 20.9 3.4 2.4 2 0 0 2 2 2 2 Ubiquitin interaction motif Transp_Tc5_C PF04236.15 OWF41881.1 - 0.17 12.3 23.9 1.7 9.1 9.3 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain RAP80_UIM PF18282.1 OWF41881.1 - 2.2 8.1 8.0 3.8 7.3 6.5 2.1 1 1 1 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif zinc-ribbons_6 PF07191.12 OWF41881.1 - 5.5 7.1 23.0 0.075 13.0 8.7 2.7 2 0 0 2 2 2 0 zinc-ribbons CBM_14 PF01607.24 OWF41882.1 - 1.3e-05 25.2 32.6 4e-05 23.7 5.0 5.0 3 2 1 4 4 4 3 Chitin binding Peritrophin-A domain Laminin_G_3 PF13385.6 OWF41882.1 - 0.0015 18.7 0.0 0.003 17.7 0.0 1.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily BTB PF00651.31 OWF41883.1 - 4.9e-21 75.0 1.1 3.7e-20 72.2 1.4 2.1 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF41883.1 - 2.1e-14 53.4 3.9 6e-13 48.8 1.6 2.7 2 0 0 2 2 2 2 BTB And C-terminal Kelch Gal11_ABD1 PF18535.1 OWF41883.1 - 0.11 12.6 0.0 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) ALG11_N PF15924.5 OWF41884.1 - 1.3e-94 316.1 0.6 1.9e-94 315.5 0.6 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OWF41884.1 - 1.3e-23 83.4 0.0 2.4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OWF41884.1 - 9.3e-12 45.5 0.0 5.5e-11 43.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 DUF2220 PF09983.9 OWF41884.1 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) Glyco_transf_4 PF13439.6 OWF41884.1 - 0.0035 17.3 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 OWF41884.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 HAT_KAT11 PF08214.11 OWF41886.1 - 2.4e-74 250.7 0.9 2.4e-74 250.7 0.9 1.9 2 0 0 2 2 2 1 Histone acetylation protein KIX PF02172.16 OWF41886.1 - 1e-39 134.6 0.7 2.6e-39 133.3 0.7 1.7 1 0 0 1 1 1 1 KIX domain DUF902 PF06001.13 OWF41886.1 - 3.3e-21 75.5 6.8 7.2e-21 74.4 6.8 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) zf-TAZ PF02135.16 OWF41886.1 - 7.2e-19 68.0 20.5 7.2e-19 68.0 20.5 3.2 3 0 0 3 3 3 1 TAZ zinc finger Bromodomain PF00439.25 OWF41886.1 - 5.9e-16 58.3 0.1 1.6e-15 56.9 0.1 1.8 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 OWF41886.1 - 9.6e-12 44.5 13.1 9.6e-12 44.5 13.1 3.3 5 0 0 5 5 5 1 Zinc finger, ZZ type KIX_2 PF16987.5 OWF41886.1 - 4.1e-05 23.5 0.6 4.1e-05 23.5 0.6 2.8 3 0 0 3 3 3 1 KIX domain Guanylate_cyc PF00211.20 OWF41887.1 - 1.4e-102 340.9 2.0 5.7e-58 195.6 0.2 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 OWF41887.1 - 4.6e-07 29.3 7.6 4.6e-07 29.3 7.6 2.8 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 OWF41887.1 - 0.0011 18.4 0.7 1.1 8.7 0.3 2.3 2 0 0 2 2 2 2 Heme NO binding associated FA_desaturase PF00487.24 OWF41887.1 - 0.7 9.7 11.0 5.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Fatty acid desaturase CUB PF00431.20 OWF41888.1 - 1.9e-26 92.5 1.6 3.1e-12 46.8 0.4 2.4 2 0 0 2 2 2 2 CUB domain LRR_4 PF12799.7 OWF41890.1 - 1.8e-09 37.7 18.8 0.0016 18.8 0.6 7.2 5 3 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF41890.1 - 3.7e-07 29.7 15.1 0.36 11.0 0.1 8.2 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 OWF41890.1 - 0.00043 20.1 2.7 0.0011 18.8 2.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 OWF41890.1 - 0.003 17.9 12.9 17 6.5 0.1 7.7 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 OWF41890.1 - 0.016 14.9 14.6 0.047 13.5 0.2 6.1 5 2 2 7 7 7 0 Leucine rich repeat CUB PF00431.20 OWF41891.1 - 0.063 13.6 0.0 0.82 10.0 0.0 2.3 2 0 0 2 2 2 0 CUB domain Inos-1-P_synth PF01658.17 OWF41891.1 - 0.096 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase ABC_tran PF00005.27 OWF41892.1 - 1.3e-36 126.1 10.5 1.4e-23 83.9 0.0 4.6 4 2 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 OWF41892.1 - 2.3e-13 50.7 1.4 0.0011 18.9 0.0 3.9 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF41892.1 - 3.4e-08 33.2 11.8 0.00017 21.1 0.0 3.6 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 OWF41892.1 - 2.5e-06 27.4 15.0 2.5e-06 27.4 15.0 3.9 3 0 0 3 3 3 1 ABC transporter AAA_15 PF13175.6 OWF41892.1 - 4.6e-05 23.3 29.4 0.009 15.8 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 OWF41892.1 - 0.00098 19.2 0.0 0.0095 16.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OWF41892.1 - 0.0027 17.4 1.5 0.061 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OWF41892.1 - 0.0044 17.4 0.3 0.059 13.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 OWF41892.1 - 0.0048 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OWF41892.1 - 0.006 16.5 0.0 0.006 16.5 0.0 2.3 3 0 0 3 3 3 1 RsgA GTPase AAA_30 PF13604.6 OWF41892.1 - 0.015 15.0 0.0 0.085 12.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF41892.1 - 0.021 15.0 0.0 0.18 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OWF41892.1 - 0.03 14.8 0.0 0.03 14.8 0.0 3.9 4 1 0 4 4 3 0 AAA domain AAA_22 PF13401.6 OWF41892.1 - 0.034 14.4 0.0 0.034 14.4 0.0 3.0 3 1 0 3 3 2 0 AAA domain AAA_16 PF13191.6 OWF41892.1 - 0.041 14.3 0.2 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.18 OWF41892.1 - 0.044 13.5 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OWF41892.1 - 0.064 13.8 0.0 0.064 13.8 0.0 3.7 4 1 1 5 5 3 0 AAA domain DUF87 PF01935.17 OWF41892.1 - 0.15 12.1 0.0 0.15 12.1 0.0 3.9 3 1 0 3 3 2 0 Helicase HerA, central domain DUF3987 PF13148.6 OWF41892.1 - 0.16 11.0 0.0 0.16 11.0 0.0 4.0 5 0 0 5 5 4 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 OWF41892.1 - 0.46 10.0 2.7 2 7.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region SURF2 PF05477.11 OWF41892.1 - 3.2 7.4 30.5 0.39 10.4 3.9 2.6 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) EF-hand_1 PF00036.32 OWF41893.1 - 4e-13 47.9 4.3 0.0017 17.8 0.0 4.3 3 1 1 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF41893.1 - 3.1e-11 42.3 5.6 0.053 13.5 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF41893.1 - 3.6e-10 39.5 7.4 0.00028 20.6 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF41893.1 - 5.8e-08 31.9 3.5 0.039 13.5 0.0 4.3 3 1 1 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF41893.1 - 4.8e-07 30.1 9.6 0.0056 17.1 5.5 3.7 1 1 3 4 4 4 4 EF-hand domain pair Caleosin PF05042.13 OWF41893.1 - 0.58 10.1 5.0 0.6 10.0 0.2 2.6 1 1 2 3 3 3 0 Caleosin related protein EF-hand_4 PF12763.7 OWF41893.1 - 0.63 10.0 5.7 0.47 10.4 0.8 2.3 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand TPR_1 PF00515.28 OWF41894.1 - 6.4e-07 28.9 1.4 2.6e-05 23.8 0.7 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF41894.1 - 2.7e-05 23.9 2.0 0.0022 18.0 0.5 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF41894.1 - 0.0037 17.5 0.1 0.012 15.9 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF41894.1 - 0.0089 16.7 0.0 0.026 15.2 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF41894.1 - 0.017 15.3 0.6 0.14 12.5 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OWF41894.1 - 0.036 13.7 0.8 0.25 11.1 0.2 2.3 1 1 1 2 2 2 0 TPR repeat Sec5 PF15469.6 OWF41894.1 - 0.046 13.5 0.6 4.7 7.0 0.0 2.4 1 1 1 2 2 2 0 Exocyst complex component Sec5 TPR_12 PF13424.6 OWF41894.1 - 0.078 13.3 0.2 0.35 11.2 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.13 OWF41894.1 - 0.19 11.8 0.1 0.44 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TTL PF03133.15 OWF41895.1 - 1.2e-63 215.0 0.5 2.8e-63 213.8 0.0 1.8 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 OWF41895.1 - 3.4e-08 33.1 0.0 0.005 16.1 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 OWF41895.1 - 2.1e-06 27.2 0.0 0.048 12.9 0.0 2.7 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OWF41895.1 - 0.0036 17.4 0.0 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 OWF41895.1 - 0.01 15.4 0.0 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Acyl-ACP_TE PF01643.17 OWF41896.1 - 2.5e-10 40.1 0.0 3.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF41896.1 - 0.00035 21.0 0.3 0.054 14.0 0.0 2.5 2 1 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF41897.1 - 6.5e-08 32.2 0.0 8.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF41897.1 - 0.0016 18.9 0.3 0.96 10.0 0.0 2.5 2 1 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF41898.1 - 0.00046 19.6 0.0 0.00067 19.0 0.0 1.4 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF41898.1 - 0.083 13.4 0.0 0.092 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily E3_UbLigase_R4 PF13764.6 OWF41899.1 - 0 1104.1 0.5 0 1104.1 0.5 2.5 3 0 0 3 3 3 1 E3 ubiquitin-protein ligase UBR4 zf-UBR PF02207.20 OWF41899.1 - 6.4e-07 29.4 15.0 6.4e-07 29.4 15.0 3.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) COG5 PF10392.9 OWF41899.1 - 0.015 15.5 1.7 0.12 12.6 1.7 2.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF4632 PF15451.6 OWF41899.1 - 0.4 10.8 4.3 4.5 7.4 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) UPF0547 PF10571.9 OWF41899.1 - 0.65 10.1 6.8 2.6 8.2 6.8 2.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF2292 PF10055.9 OWF41900.1 - 9.8e-06 25.1 17.5 5.7 6.7 0.2 9.9 4 4 7 11 11 11 2 Uncharacterized small protein (DUF2292) Rotavirus_VP7 PF05868.11 OWF41900.1 - 0.0015 18.0 4.7 1.6 8.0 0.5 4.1 1 1 4 5 5 5 3 Rotavirus major outer capsid protein VP7 DUF613 PF04764.12 OWF41900.1 - 0.01 16.0 0.0 26 5.0 0.0 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF613) TusA PF01206.17 OWF41900.1 - 0.1 12.5 0.2 25 4.8 0.0 3.6 3 1 2 5 5 5 0 Sulfurtransferase TusA RNA_pol_Rpc4 PF05132.14 OWF41900.1 - 0.11 12.9 0.3 18 5.8 0.1 3.6 1 1 0 2 2 2 0 RNA polymerase III RPC4 Ribosomal_S25 PF03297.15 OWF41900.1 - 0.52 10.5 11.1 33 4.8 0.4 4.8 1 1 4 5 5 5 0 S25 ribosomal protein YjbT PF17089.5 OWF41901.1 - 0.0032 17.4 19.2 34 4.5 0.2 8.0 2 2 6 9 9 9 0 Uncharacterised protein family Pertussis_S1 PF02917.14 OWF41901.1 - 0.0033 17.2 7.3 4.9 6.9 0.1 3.6 2 1 2 4 4 4 3 Pertussis toxin, subunit 1 Organ_specific PF10950.8 OWF41901.1 - 0.041 14.6 16.2 32 5.3 0.0 7.7 2 2 6 8 8 8 0 Organ specific protein F-box PF00646.33 OWF41901.1 - 0.075 12.9 0.1 14 5.7 0.1 3.2 2 0 0 2 2 2 0 F-box domain PAN_2 PF08276.11 OWF41901.1 - 0.34 11.0 6.1 6.1 7.0 0.1 4.2 3 1 1 4 4 4 0 PAN-like domain Cys_box PF17869.1 OWF41901.1 - 3.4 7.9 10.1 19 5.4 0.2 4.2 3 1 1 4 4 4 0 Anosmin cysteine rich domain LIM PF00412.22 OWF41902.1 - 2.4e-30 104.6 19.8 9.5e-16 57.8 3.3 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 OWF41902.1 - 7.3e-18 64.2 2.7 1.2e-17 63.5 2.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF41902.1 - 9.1e-05 22.3 0.1 0.00018 21.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain NinD PF17466.2 OWF41902.1 - 1.3 9.1 5.0 1.4 9.1 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function Drf_FH1 PF06346.12 OWF41905.1 - 3.7 7.2 55.0 3.9 7.2 32.3 2.3 1 1 1 2 2 2 0 Formin Homology Region 1 FlaC_arch PF05377.11 OWF41906.1 - 1.9e-08 34.6 21.5 2.9 8.4 0.2 10.2 1 1 10 12 12 12 4 Flagella accessory protein C (FlaC) Peripla_BP_7 PF18610.1 OWF41906.1 - 0.00025 21.1 11.4 74 3.6 0.1 8.7 1 1 12 13 13 13 0 Periplasmic binding protein domain COX5A PF02284.16 OWF41906.1 - 0.00062 19.7 2.8 66 3.6 0.0 5.0 1 1 5 6 6 6 0 Cytochrome c oxidase subunit Va DUF2235 PF09994.9 OWF41906.1 - 0.014 14.8 2.9 31 3.8 1.1 6.2 1 1 2 3 3 3 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) LIM PF00412.22 OWF41907.1 - 6.4e-31 106.4 16.4 1.5e-16 60.4 1.9 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 OWF41907.1 - 2.3e-18 65.8 2.9 3.9e-18 65.0 2.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF41907.1 - 1.4e-05 24.9 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF2541 PF10807.8 OWF41907.1 - 0.059 13.5 1.0 0.09 12.9 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) DUF4820 PF16091.5 OWF41907.1 - 0.1 11.9 2.7 0.15 11.4 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Jas PF16135.5 OWF41907.1 - 0.32 11.2 5.2 13 6.1 5.2 2.7 1 1 0 1 1 1 0 TPL-binding domain in jasmonate signalling TNFR_c6 PF00020.18 OWF41907.1 - 0.45 11.0 4.6 5.8 7.4 0.7 3.0 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region PNISR PF15996.5 OWF41907.1 - 0.63 10.3 7.0 7 6.9 5.7 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF1289 PF06945.13 OWF41907.1 - 0.88 9.4 9.4 0.27 11.1 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) IBR PF01485.21 OWF41908.1 - 5.4e-08 32.9 34.0 4.1e-06 26.9 8.8 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain ubiquitin PF00240.23 OWF41908.1 - 3.9e-07 29.7 0.0 9.1e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OWF41908.1 - 0.0078 16.7 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain zf-RING_UBOX PF13445.6 OWF41909.1 - 4.2e-08 33.1 12.5 4.2e-08 33.1 12.5 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF41909.1 - 8.4e-08 32.0 13.1 8.4e-08 32.0 13.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF41909.1 - 1.2e-07 31.5 10.7 1.2e-07 31.5 10.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41909.1 - 7.2e-07 29.0 10.8 7.2e-07 29.0 10.8 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF41909.1 - 7.7e-07 29.3 14.9 7.7e-07 29.3 14.9 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF41909.1 - 6.7e-06 25.9 12.4 6.7e-06 25.9 12.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF41909.1 - 7.9e-05 22.7 12.1 7.9e-05 22.7 12.1 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF41909.1 - 0.00068 19.6 12.6 0.00068 19.6 12.6 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.24 OWF41909.1 - 0.0049 17.0 9.9 0.0049 17.0 9.9 2.9 2 1 0 2 2 2 1 B-box zinc finger NHL PF01436.21 OWF41909.1 - 0.1 12.7 0.0 0.54 10.4 0.0 2.4 1 0 0 1 1 1 0 NHL repeat zf-C3HC4_3 PF13920.6 OWF41910.1 - 5.9e-09 35.7 9.6 5.9e-09 35.7 9.6 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41910.1 - 7.8e-08 32.2 5.9 7.8e-08 32.2 5.9 3.2 1 1 1 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF41910.1 - 2.6e-07 30.4 12.8 2.6e-07 30.4 12.8 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF41910.1 - 1.1e-06 28.5 9.4 1.1e-06 28.5 9.4 3.4 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF41910.1 - 1.4e-06 28.5 10.1 1.4e-06 28.5 10.1 3.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF41910.1 - 2e-05 24.3 10.7 2e-05 24.3 10.7 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF41910.1 - 0.00039 20.5 10.6 0.00039 20.5 10.6 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF41910.1 - 0.0016 18.3 9.6 0.0016 18.3 9.6 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SGL PF08450.12 OWF41910.1 - 0.025 14.2 0.0 0.07 12.7 0.0 1.7 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF41910.1 - 0.033 14.2 4.4 55 4.1 0.0 4.7 4 0 0 4 4 4 0 NHL repeat DUF2197 PF09963.9 OWF41910.1 - 0.037 14.3 2.6 0.042 14.1 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) RasGEF PF00617.19 OWF41911.1 - 1.2e-48 165.7 0.6 3.3e-48 164.2 0.5 1.8 1 1 0 1 1 1 1 RasGEF domain PH PF00169.29 OWF41911.1 - 0.00012 22.5 0.0 0.00033 21.1 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF3492 PF11997.8 OWF41911.1 - 0.032 14.0 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) PTS_2-RNA PF01885.16 OWF41912.1 - 2.4e-14 53.8 0.0 3.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ephrin_rec_like PF07699.13 OWF41913.1 - 3.7e-27 93.8 58.5 4e-13 48.9 10.5 7.5 4 1 1 5 5 5 3 Putative ephrin-receptor like HYR PF02494.16 OWF41913.1 - 2.2e-24 85.5 14.8 2.8e-16 59.6 0.4 3.9 3 1 1 4 4 4 2 HYR domain TSP_1 PF00090.19 OWF41913.1 - 3.7e-08 33.5 7.4 3.7e-08 33.5 7.4 4.9 5 0 0 5 5 5 1 Thrombospondin type 1 domain hEGF PF12661.7 OWF41913.1 - 4.3e-06 27.2 12.8 0.06 14.0 2.6 5.5 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 OWF41913.1 - 1.1e-05 25.6 31.7 2.1e-05 24.7 2.6 5.8 4 0 0 4 4 4 2 EGF-like domain Sushi PF00084.20 OWF41913.1 - 1.9e-05 25.2 3.4 1.9e-05 25.2 3.4 7.3 7 0 0 7 7 7 3 Sushi repeat (SCR repeat) DUF2318 PF10080.9 OWF41913.1 - 5.8 7.1 27.3 1.6 8.9 3.1 5.6 5 1 1 6 6 6 0 Predicted membrane protein (DUF2318) Glyco_trans_2_3 PF13632.6 OWF41915.1 - 6.4e-34 117.6 0.7 6.4e-34 117.6 0.7 2.0 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF41915.1 - 6.9e-08 32.7 0.0 9.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HMA PF00403.26 OWF41916.1 - 1.7e-83 275.0 11.2 5.9e-13 49.1 0.0 7.9 7 0 0 7 7 7 7 Heavy-metal-associated domain Hydrolase PF00702.26 OWF41916.1 - 2.3e-55 188.2 1.6 4.8e-55 187.1 1.6 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OWF41916.1 - 1.7e-47 161.3 2.6 1.7e-47 161.3 2.6 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OWF41916.1 - 2.8e-06 27.2 2.5 7.6e-05 22.6 0.7 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OWF41916.1 - 0.00012 22.2 0.3 0.00037 20.6 0.3 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OWF41916.1 - 0.00048 20.2 0.2 0.0046 17.1 0.2 2.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2997 PF11211.8 OWF41916.1 - 0.0025 17.5 22.4 0.67 9.8 0.2 6.9 7 0 0 7 7 7 2 Protein of unknown function (DUF2997) Poly_export PF02563.16 OWF41916.1 - 0.014 15.6 0.0 18 5.7 0.0 5.0 6 0 0 6 6 5 0 Polysaccharide biosynthesis/export protein NAC PF01849.18 OWF41916.1 - 0.066 13.2 0.7 4.3 7.4 0.0 3.5 3 0 0 3 3 3 0 NAC domain HAD PF12710.7 OWF41916.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-LITAF-like PF10601.9 OWF41916.1 - 6.4 7.1 13.7 11 6.4 0.1 5.4 6 0 0 6 6 6 0 LITAF-like zinc ribbon domain Methyltransf_FA PF12248.8 OWF41917.1 - 1.6e-35 121.5 0.0 3e-16 59.6 0.0 2.4 2 0 0 2 2 2 2 Farnesoic acid 0-methyl transferase Gal_Lectin PF02140.18 OWF41917.1 - 8.7e-34 115.8 10.2 1.5e-17 63.8 2.3 2.8 2 0 0 2 2 2 2 Galactose binding lectin domain DUF4513 PF14983.6 OWF41917.1 - 0.013 15.6 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4513) CIA30 PF08547.12 OWF41917.1 - 0.023 14.7 0.0 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) Syncollin PF15138.6 OWF41917.1 - 0.027 14.7 3.6 15 5.8 0.0 4.2 3 2 1 4 4 4 0 Syncollin Fungal_lectin_2 PF18647.1 OWF41917.1 - 0.06 13.8 4.9 27 5.3 0.0 4.3 4 0 0 4 4 4 0 Alpha-galactosyl-binding fungal lectin Brr6_like_C_C PF10104.9 OWF41917.1 - 0.2 11.4 3.9 9.4 6.0 0.8 2.5 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain 7tm_1 PF00001.21 OWF41918.1 - 1.7e-18 66.9 4.7 1.8e-18 66.8 4.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sri PF10327.9 OWF41918.1 - 0.0028 16.9 0.9 0.0035 16.6 0.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Claudin_2 PF13903.6 OWF41918.1 - 0.0047 16.7 0.0 0.0067 16.2 0.0 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PhoLip_ATPase_C PF16212.5 OWF41918.1 - 0.0096 15.7 2.0 0.0096 15.7 2.0 1.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Sigma_reg_N PF13800.6 OWF41918.1 - 0.053 13.8 1.8 0.63 10.4 0.5 2.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal ABC2_membrane_3 PF12698.7 OWF41918.1 - 0.16 11.1 2.4 0.25 10.4 2.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Prominin PF05478.11 OWF41918.1 - 0.17 9.8 0.4 0.18 9.7 0.4 1.2 1 0 0 1 1 1 0 Prominin DUF2207 PF09972.9 OWF41918.1 - 0.26 10.0 3.9 0.11 11.3 1.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PRA1 PF03208.19 OWF41918.1 - 0.48 10.0 4.4 0.32 10.6 2.4 1.6 2 0 0 2 2 2 0 PRA1 family protein zf-LITAF-like PF10601.9 OWF41918.1 - 1.2 9.4 4.3 1.7 9.0 0.3 2.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-C3HC4 PF00097.25 OWF41919.1 - 4.2e-09 36.1 7.9 4.2e-09 36.1 7.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41919.1 - 2.3e-08 33.9 7.5 2.3e-08 33.9 7.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 OWF41919.1 - 2.5e-07 30.7 20.0 2.7e-05 24.2 6.9 4.1 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.6 OWF41919.1 - 7.8e-07 28.8 2.6 7.8e-07 28.8 2.6 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF41919.1 - 1.4e-06 28.3 8.8 1.4e-06 28.3 8.8 3.9 3 2 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF41919.1 - 1.5e-06 28.4 7.7 1.5e-06 28.4 7.7 4.1 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OWF41919.1 - 1.3e-05 25.0 7.0 1.3e-05 25.0 7.0 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF41919.1 - 1.8e-05 24.5 5.8 1.8e-05 24.5 5.8 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41919.1 - 0.00021 21.1 3.4 0.00021 21.1 3.4 3.6 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 Chorein_N PF12624.7 OWF41919.1 - 0.057 13.5 0.8 0.13 12.4 0.0 1.9 2 1 0 2 2 2 0 N-terminal region of Chorein or VPS13 zf-C3HC4 PF00097.25 OWF41920.1 - 7.4e-08 32.1 11.1 7.4e-08 32.1 11.1 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF41920.1 - 2.4e-06 27.4 10.5 2.4e-06 27.4 10.5 2.4 3 0 0 3 3 1 1 RING-type zinc-finger zf-B_box PF00643.24 OWF41920.1 - 2.5e-06 27.5 20.0 9.7e-05 22.4 7.3 3.8 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_4 PF15227.6 OWF41920.1 - 2.9e-05 24.1 11.9 2.9e-05 24.1 11.9 3.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING SGL PF08450.12 OWF41920.1 - 3e-05 23.7 0.0 0.038 13.6 0.0 2.5 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region zf-RING_2 PF13639.6 OWF41920.1 - 8.1e-05 22.9 11.1 8.1e-05 22.9 11.1 3.7 3 0 0 3 3 3 1 Ring finger domain NHL PF01436.21 OWF41920.1 - 0.00027 20.8 1.7 2.3 8.4 0.0 4.7 4 0 0 4 4 4 1 NHL repeat zf-RING_5 PF14634.6 OWF41920.1 - 0.00034 20.5 10.3 0.00034 20.5 10.3 3.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF41920.1 - 0.0014 18.5 8.4 0.0014 18.5 8.4 3.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF41920.1 - 0.0067 16.3 6.9 0.0067 16.3 6.9 3.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OWF41920.1 - 0.0074 16.1 12.4 0.0074 16.1 12.4 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) P4Ha_N PF08336.11 OWF41920.1 - 0.12 12.4 1.1 0.23 11.4 1.1 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region LapA_dom PF06305.11 OWF41921.1 - 0.47 10.3 1.5 0.94 9.3 1.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 OWF41922.1 - 0.016 16.1 1.8 0.22 12.4 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OWF41922.1 - 0.025 14.3 1.1 0.025 14.3 1.1 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DAP10 PF07213.11 OWF41922.1 - 0.35 10.8 3.4 0.28 11.2 1.3 1.8 1 1 1 2 2 2 0 DAP10 membrane protein SKG6 PF08693.10 OWF41922.1 - 7.6 6.0 12.4 0.08 12.4 3.3 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Methyltransf_7 PF03492.15 OWF41923.1 - 1.7e-25 89.9 0.1 5.6e-14 52.1 0.0 2.1 1 1 0 2 2 2 2 SAM dependent carboxyl methyltransferase 7tm_2 PF00002.24 OWF41924.1 - 7.1e-76 254.7 19.6 9.6e-76 254.3 19.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF41924.1 - 9.4e-17 61.1 5.2 9.4e-17 61.1 5.2 2.0 2 0 0 2 2 2 1 Hormone receptor domain DUF1117 PF06547.12 OWF41924.1 - 0.7 10.5 3.3 1.5 9.4 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Bac_export_2 PF01312.19 OWF41924.1 - 1.5 8.0 5.2 2.9 7.0 5.2 1.4 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Death PF00531.22 OWF41925.1 - 0.0028 17.8 0.0 0.013 15.7 0.0 2.2 1 0 0 1 1 1 1 Death domain CSD PF00313.22 OWF41925.1 - 0.048 13.5 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain ABC_membrane PF00664.23 OWF41926.1 - 1.8e-237 785.5 54.3 1.2e-63 215.4 4.4 4.5 4 1 1 5 5 5 4 ABC transporter transmembrane region ABC_tran PF00005.27 OWF41926.1 - 1.5e-147 485.4 0.9 8.3e-36 123.5 0.0 4.4 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 OWF41926.1 - 3.4e-31 108.4 9.9 7.7e-07 28.8 0.0 7.2 4 4 2 6 6 6 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OWF41926.1 - 3.7e-18 66.5 7.2 0.0036 17.7 0.1 5.3 4 2 0 4 4 4 4 AAA ATPase domain ABC_ATPase PF09818.9 OWF41926.1 - 8.5e-17 61.1 3.1 0.00023 20.1 0.0 6.1 7 0 0 7 7 7 4 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OWF41926.1 - 3.2e-14 53.2 0.0 0.023 14.6 0.0 4.5 4 0 0 4 4 4 4 RsgA GTPase AAA_22 PF13401.6 OWF41926.1 - 5.1e-14 52.7 7.2 0.085 13.1 0.1 6.3 4 4 0 4 4 4 4 AAA domain Rad17 PF03215.15 OWF41926.1 - 1.4e-12 47.9 1.9 0.15 11.9 0.0 4.8 4 0 0 4 4 4 4 Rad17 P-loop domain AAA_15 PF13175.6 OWF41926.1 - 9.3e-12 45.3 0.1 0.29 10.8 0.0 4.3 4 0 0 4 4 4 4 AAA ATPase domain AAA_28 PF13521.6 OWF41926.1 - 3.3e-11 43.7 1.8 0.66 10.2 0.1 5.8 6 0 0 6 6 6 3 AAA domain AAA_18 PF13238.6 OWF41926.1 - 8.5e-11 42.5 0.1 1.2 9.7 0.0 4.8 4 0 0 4 4 4 3 AAA domain AAA_30 PF13604.6 OWF41926.1 - 9e-11 41.8 11.7 0.022 14.5 0.3 5.8 4 2 0 4 4 4 4 AAA domain DUF87 PF01935.17 OWF41926.1 - 2e-10 41.2 6.0 0.35 10.9 0.0 6.0 5 1 0 5 5 5 3 Helicase HerA, central domain G-alpha PF00503.20 OWF41926.1 - 3.2e-10 39.7 0.1 0.32 10.1 0.0 4.2 4 0 0 4 4 4 4 G-protein alpha subunit Zeta_toxin PF06414.12 OWF41926.1 - 3.6e-10 39.4 7.8 0.15 11.3 0.0 6.0 7 0 0 7 7 7 4 Zeta toxin AAA_5 PF07728.14 OWF41926.1 - 4.2e-10 39.8 1.1 0.89 9.5 0.0 6.4 7 0 0 7 7 6 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OWF41926.1 - 6e-10 38.9 0.9 1.1 8.7 0.0 4.4 4 0 0 4 4 4 4 P-loop containing dynein motor region AAA_21 PF13304.6 OWF41926.1 - 1.3e-09 38.3 0.1 1 9.1 0.0 7.3 8 0 0 8 8 8 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OWF41926.1 - 9.1e-09 35.4 15.4 0.74 10.1 0.3 6.6 4 4 0 4 4 4 4 Putative exonuclease SbcCD, C subunit PRK PF00485.18 OWF41926.1 - 1e-08 35.2 0.6 1.3 8.7 0.0 4.4 4 0 0 4 4 4 2 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 OWF41926.1 - 3.1e-08 33.2 10.6 0.44 10.3 0.1 4.6 4 0 0 4 4 4 4 P-loop containing region of AAA domain AAA PF00004.29 OWF41926.1 - 9.6e-08 32.5 14.0 0.68 10.4 0.2 7.7 4 4 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 OWF41926.1 - 1.8e-07 31.1 5.4 1.2 8.7 0.2 4.8 4 2 0 4 4 4 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 OWF41926.1 - 2.2e-07 31.1 0.0 3 8.0 0.0 4.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 OWF41926.1 - 3.4e-07 30.6 0.6 8.2 6.9 0.0 5.0 4 0 0 4 4 4 0 RNA helicase MMR_HSR1 PF01926.23 OWF41926.1 - 4.3e-07 30.0 0.1 5.1 7.2 0.0 4.8 4 0 0 4 4 4 0 50S ribosome-binding GTPase DUF815 PF05673.13 OWF41926.1 - 1.1e-06 28.0 0.4 1.3 8.1 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF815) tRNA_lig_kinase PF08303.11 OWF41926.1 - 1.2e-06 28.7 0.8 11 6.1 0.0 4.7 4 0 0 4 4 4 0 tRNA ligase kinase domain AAA_24 PF13479.6 OWF41926.1 - 1.5e-06 28.1 0.0 9 6.0 0.0 4.4 4 0 0 4 4 4 0 AAA domain APS_kinase PF01583.20 OWF41926.1 - 5.2e-06 26.4 2.9 1.5 8.7 0.1 5.0 5 0 0 5 5 5 1 Adenylylsulphate kinase AAA_25 PF13481.6 OWF41926.1 - 7.2e-06 25.7 0.1 17 4.9 0.0 5.0 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 OWF41926.1 - 3.2e-05 23.8 0.0 10 5.8 0.0 4.8 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 OWF41926.1 - 4.1e-05 23.6 3.6 16 5.4 0.0 4.6 4 0 0 4 4 4 0 NACHT domain DUF2852 PF11014.8 OWF41926.1 - 0.00015 21.9 5.5 2.3 8.4 0.1 4.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2852) MeaB PF03308.16 OWF41926.1 - 0.00019 20.5 1.5 2.9 6.8 0.0 4.2 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 OWF41926.1 - 0.0012 18.6 0.4 50 3.4 0.0 4.5 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 OWF41926.1 - 0.0045 16.2 5.8 11 5.1 0.0 4.4 4 0 0 4 4 4 0 NB-ARC domain AAA_23 PF13476.6 OWF41926.1 - 0.0053 17.3 3.9 65 3.9 0.0 4.5 4 0 0 4 4 4 0 AAA domain Herpes_Helicase PF02689.14 OWF41926.1 - 0.0086 14.1 0.0 4.8 5.0 0.0 3.1 4 0 0 4 4 4 0 Helicase AAA_17 PF13207.6 OWF41926.1 - 0.0094 16.4 1.2 85 3.6 0.0 5.1 5 0 0 5 5 4 0 AAA domain dNK PF01712.19 OWF41926.1 - 0.02 14.7 0.3 1.3e+02 2.3 0.0 4.4 4 0 0 4 4 4 0 Deoxynucleoside kinase FeoB_N PF02421.18 OWF41926.1 - 0.022 14.3 0.0 36 3.8 0.0 3.9 4 0 0 4 4 4 0 Ferrous iron transport protein B FimH_man-bind PF09160.10 OWF41926.1 - 0.023 14.4 0.0 31 4.2 0.0 4.5 5 0 0 5 5 4 0 FimH, mannose binding RepB-RCR_reg PF10723.9 OWF41926.1 - 0.026 14.4 1.5 1.3e+02 2.7 0.0 4.4 4 0 0 4 4 4 0 Replication regulatory protein RepB Septin PF00735.18 OWF41926.1 - 0.026 13.8 1.8 23 4.2 0.0 4.0 4 0 0 4 4 4 0 Septin PduV-EutP PF10662.9 OWF41926.1 - 0.058 13.1 6.0 24 4.6 0.0 4.3 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OWF41926.1 - 0.084 12.6 2.0 1e+02 2.6 0.1 4.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Fer4_NifH PF00142.18 OWF41926.1 - 0.11 11.9 0.2 33 3.8 0.0 3.3 4 0 0 4 4 4 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FtsK_SpoIIIE PF01580.18 OWF41926.1 - 0.13 11.6 6.7 11 5.3 0.1 4.0 4 0 0 4 4 4 0 FtsK/SpoIIIE family Pox_I5 PF04713.12 OWF41926.1 - 0.19 11.8 1.6 16 5.7 0.0 3.8 3 0 0 3 3 3 0 Poxvirus protein I5 TsaE PF02367.17 OWF41926.1 - 0.45 10.5 2.8 65 3.6 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2057 PF09829.9 OWF41926.1 - 0.46 10.6 1.6 29 4.8 0.0 3.1 4 0 0 4 4 2 0 Uncharacterized protein conserved in bacteria (DUF2057) CoaE PF01121.20 OWF41926.1 - 0.74 9.5 5.0 38 3.9 0.1 3.9 4 0 0 4 4 4 0 Dephospho-CoA kinase HTH_20 PF12840.7 OWF41926.1 - 2.7 8.1 5.9 14 5.9 0.2 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain IPK PF03770.16 OWF41927.1 - 6.3e-53 179.6 1.4 1.2e-52 178.7 1.4 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase zf-B_box PF00643.24 OWF41928.1 - 2.9e-05 24.1 6.2 5.7e-05 23.2 6.2 1.5 1 0 0 1 1 1 1 B-box zinc finger Antimicrobial_3 PF08025.11 OWF41929.1 - 0.00084 19.2 4.4 55 3.8 0.1 6.8 3 2 7 10 10 10 1 Spider antimicrobial peptide Tn7_TnsC_Int PF11426.8 OWF41929.1 - 0.036 14.2 6.4 35 4.7 0.1 4.9 2 2 2 5 5 5 0 Tn7 transposition regulator TnsC DUF1419 PF07215.11 OWF41929.1 - 0.12 12.5 10.8 10 6.2 0.4 4.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1419) SWIB PF02201.18 OWF41931.1 - 1.1e-22 79.7 0.1 2.1e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain THAP PF05485.12 OWF41932.1 - 9.5e-11 42.5 0.2 1.7e-10 41.7 0.0 1.5 2 0 0 2 2 2 1 THAP domain DUF4357 PF14267.6 OWF41933.1 - 6.1e-10 38.9 30.8 29 4.7 0.5 13.6 1 1 26 27 27 27 26 Domain of unknown function (DUF4357) Asp PF00026.23 OWF41934.1 - 3.5e-44 151.5 0.6 4.4e-44 151.2 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 OWF41934.1 - 1.3e-13 51.0 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 OWF41934.1 - 6.3e-09 36.3 0.0 0.0036 17.5 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal FAM176 PF14851.6 OWF41934.1 - 0.045 13.4 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 FAM176 family FA_hydroxylase PF04116.13 OWF41935.1 - 3.3e-25 89.0 21.7 5.3e-25 88.3 19.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DHR-2 PF06920.13 OWF41937.1 - 2.8e-191 636.8 0.3 4.9e-191 636.0 0.3 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 OWF41937.1 - 1.9e-49 168.1 0.1 3.8e-49 167.1 0.1 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 OWF41937.1 - 8.2e-26 90.6 2.1 8.2e-26 90.6 2.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 OWF41937.1 - 1e-05 24.6 0.1 3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 DOCK N-terminus Ank_5 PF13857.6 OWF41937.1 - 0.14 12.5 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) C2 PF00168.30 OWF41938.1 - 1.1e-11 45.0 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Snf7 PF03357.21 OWF41938.1 - 0.0033 17.0 3.7 0.0033 17.0 3.7 3.3 3 1 1 4 4 4 1 Snf7 DUF1771 PF08590.10 OWF41938.1 - 0.018 15.4 2.1 0.018 15.4 2.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) DUF357 PF04010.13 OWF41938.1 - 0.063 13.4 2.2 3.6 7.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF357) Cep57_MT_bd PF06657.13 OWF41938.1 - 1.6 9.2 9.5 0.19 12.2 4.0 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 NusG_II PF07009.11 OWF41939.1 - 2.3 8.5 9.7 8.9 6.6 0.3 3.7 1 1 4 5 5 5 0 NusG domain II HPS3_Mid PF14762.6 OWF41939.1 - 8 5.1 6.7 5 5.8 0.4 2.7 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3, middle region NusG_II PF07009.11 OWF41940.1 - 0.075 13.2 8.6 6.1 7.1 0.1 4.4 1 1 4 6 6 6 0 NusG domain II 7tm_1 PF00001.21 OWF41941.1 - 1.4e-43 149.1 18.6 1.8e-43 148.7 18.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF41941.1 - 5.6e-09 35.8 23.7 7.8e-09 35.3 23.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Usp PF00582.26 OWF41942.1 - 3.3e-18 66.6 0.2 3.6e-18 66.4 0.2 1.0 1 0 0 1 1 1 1 Universal stress protein family DUF4539 PF15072.6 OWF41943.1 - 3.4e-05 23.8 0.5 6.3e-05 22.9 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) UbiA PF01040.18 OWF41945.1 - 4.9e-51 173.4 13.4 6.2e-51 173.1 13.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.9 OWF41945.1 - 0.0005 19.8 0.6 0.0005 19.8 0.6 2.3 2 0 0 2 2 2 1 Oligosaccaryltransferase DDA1 PF10172.9 OWF41945.1 - 0.06 13.6 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase FUR PF01475.19 OWF41945.1 - 0.13 12.4 0.3 0.21 11.7 0.3 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family COG5 PF10392.9 OWF41946.1 - 1.7e-31 109.1 1.7 1.7e-31 109.1 1.7 3.0 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 OWF41946.1 - 2e-06 27.8 0.2 1.2e-05 25.2 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 OWF41946.1 - 6.3e-05 23.1 0.5 0.00039 20.5 0.5 2.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 CLZ PF16526.5 OWF41946.1 - 0.0053 17.1 0.1 0.033 14.5 0.1 2.5 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4693 PF15764.5 OWF41946.1 - 0.069 12.7 7.4 0.56 9.7 0.2 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4693) DUF4640 PF15480.6 OWF41946.1 - 0.099 12.4 0.0 0.37 10.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) DUF3135 PF11333.8 OWF41946.1 - 0.12 12.6 2.0 12 6.3 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) MitMem_reg PF13012.6 OWF41946.1 - 0.18 12.2 2.2 0.48 10.9 0.4 2.8 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Dus PF01207.17 OWF41947.1 - 1.9e-72 244.0 0.1 2.3e-72 243.7 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OWF41947.1 - 4.7e-06 26.2 0.0 8.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 OWF41947.1 - 0.0011 18.3 0.1 0.0028 17.0 0.0 1.7 1 1 0 1 1 1 1 Thiamine monophosphate synthase SOR_SNZ PF01680.17 OWF41947.1 - 0.066 13.0 0.1 0.15 11.8 0.1 1.5 2 0 0 2 2 2 0 SOR/SNZ family DHO_dh PF01180.21 OWF41947.1 - 0.13 11.5 0.0 1.1 8.4 0.0 1.9 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase DUF561 PF04481.12 OWF41947.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF561) OSR1_C PF12202.8 OWF41948.1 - 0.0014 18.8 0.1 0.0038 17.4 0.1 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase PF00069.25 OWF41949.1 - 3.4e-57 193.8 0.1 6.5e-57 192.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF41949.1 - 5.2e-42 143.9 0.1 8.5e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 OWF41949.1 - 1.6e-28 98.7 3.5 4.4e-28 97.3 3.5 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Sod_Cu PF00080.20 OWF41950.1 - 1.9e-35 122.1 27.6 9e-28 97.2 9.6 7.5 3 2 1 4 4 4 2 Copper/zinc superoxide dismutase (SODC) ZapB PF06005.12 OWF41950.1 - 0.053 14.0 0.0 0.089 13.2 0.0 1.3 1 0 0 1 1 1 0 Cell division protein ZapB NPV_P10 PF05531.12 OWF41950.1 - 0.12 12.8 0.2 0.22 12.0 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 OWF41950.1 - 0.74 10.1 2.8 0.4 10.9 0.5 1.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF2024 PF09630.10 OWF41951.1 - 0.028 14.3 4.9 13 5.8 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF2024) Tom37 PF10568.9 OWF41951.1 - 0.093 13.0 0.1 10 6.5 0.0 3.1 2 1 1 3 3 3 0 Outer mitochondrial membrane transport complex protein DUF3862 PF12978.7 OWF41951.1 - 0.12 12.2 8.6 0.69 9.7 0.5 3.3 1 1 3 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3862) DUF4172 PF13776.6 OWF41951.1 - 0.14 12.5 0.1 9.6 6.6 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4172) SHOCT PF09851.9 OWF41951.1 - 0.17 11.7 9.9 2.2 8.1 0.1 4.9 5 0 0 5 5 5 0 Short C-terminal domain DUF5442 PF17514.2 OWF41951.1 - 0.38 11.0 6.0 19 5.5 0.3 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5442) PP-binding PF00550.25 OWF41952.1 - 0.013 15.8 0.1 0.042 14.2 0.1 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site GLTT PF01744.20 OWF41956.1 - 1.1e-39 133.3 58.7 3.2e-05 23.6 0.5 12.0 3 3 7 13 13 13 11 GLTT repeat (6 copies) Pentapeptide_4 PF13599.6 OWF41956.1 - 2e-05 24.6 14.9 12 6.1 0.2 5.3 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) NMT1 PF09084.11 OWF41956.1 - 7 6.5 17.0 39 4.1 4.1 4.1 1 1 3 4 4 4 0 NMT1/THI5 like GLTT PF01744.20 OWF41957.1 - 3.1e-21 74.6 53.3 0.00012 21.7 1.5 9.7 3 2 7 11 11 11 11 GLTT repeat (6 copies) Pentapeptide_4 PF13599.6 OWF41957.1 - 2e-06 27.9 7.6 0.08 13.1 0.2 3.8 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) NMT1 PF09084.11 OWF41957.1 - 0.039 13.9 12.2 3.4 7.6 0.3 3.6 1 1 2 3 3 3 0 NMT1/THI5 like Streptin-Immun PF11083.8 OWF41957.1 - 0.044 14.2 26.6 0.59 10.6 3.5 4.3 1 1 4 5 5 5 0 Lantibiotic streptin immunity protein GLTT PF01744.20 OWF41958.1 - 3.6e-24 83.9 36.9 5.5e-06 26.0 0.1 8.6 4 2 4 9 9 9 7 GLTT repeat (6 copies) Pentapeptide_4 PF13599.6 OWF41958.1 - 0.00024 21.2 4.6 1.1 9.4 2.0 3.7 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) Streptin-Immun PF11083.8 OWF41958.1 - 0.16 12.4 15.1 2.4 8.6 3.8 3.7 1 1 4 5 5 5 0 Lantibiotic streptin immunity protein DNA_pol3_theta PF06440.11 OWF41958.1 - 0.25 11.0 10.1 41 3.9 0.1 5.6 4 1 3 7 7 7 0 DNA polymerase III, theta subunit SPECT1 PF18680.1 OWF41959.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 MFS_1 PF07690.16 OWF41961.1 - 1e-17 64.2 24.2 1e-17 64.2 24.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF41962.1 - 1.2e-12 47.5 19.0 1.2e-12 47.5 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF41962.1 - 4.1e-06 25.9 3.4 4.1e-06 25.9 3.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MPS-4 PF17523.2 OWF41963.1 - 4.8e-05 23.4 9.4 0.46 10.6 0.1 5.5 3 1 1 5 5 5 4 MinK-related peptide, potassium channel accessory sub-unit protein 4 Nrap PF03813.14 OWF41963.1 - 0.0002 21.4 0.0 18 5.3 0.0 5.2 1 1 2 3 3 3 3 Nrap protein domain 1 IMPDH PF00478.25 OWF41964.1 - 2.9e-138 460.6 5.4 3.6e-138 460.3 5.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OWF41964.1 - 2.9e-10 40.4 0.0 0.0018 18.7 0.0 3.1 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 OWF41964.1 - 6.7e-10 38.9 4.0 2.1e-07 30.7 1.8 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OWF41964.1 - 3.5e-08 32.9 1.3 6.1e-08 32.1 1.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OWF41964.1 - 5e-07 29.4 3.0 1.1e-05 25.0 3.0 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 OWF41964.1 - 0.0011 18.3 2.4 0.0025 17.1 2.3 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 OWF41964.1 - 0.0013 18.0 0.3 0.0028 16.9 0.3 1.6 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 OWF41964.1 - 0.065 12.4 1.5 3.3 6.8 0.0 3.2 2 1 1 4 4 4 0 Indole-3-glycerol phosphate synthase DUF561 PF04481.12 OWF41964.1 - 0.1 11.8 0.6 0.24 10.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) YpsA PF06908.11 OWF41964.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Sulfotransfer_1 PF00685.27 OWF41965.1 - 7.5e-19 68.2 0.0 2.6e-18 66.4 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF41965.1 - 1.5e-13 51.6 0.0 7.5e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Baculo_PEP_C PF04513.12 OWF41966.1 - 2.6e-09 37.2 65.9 0.11 12.5 21.6 5.2 1 1 2 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 OWF41966.1 - 5.3e-07 29.6 31.8 9.2e-07 28.8 31.8 1.5 1 1 0 1 1 1 1 Bacterial collagen, middle region Bacillus_HBL PF05791.11 OWF41966.1 - 0.0013 18.6 5.6 0.094 12.5 2.0 2.0 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 OWF41966.1 - 0.0037 17.3 2.8 0.043 13.9 1.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 OWF41966.1 - 0.0096 16.3 1.1 0.32 11.4 0.6 2.7 1 1 1 2 2 2 2 Syntaxin-like protein CK2S PF15011.6 OWF41966.1 - 0.011 15.7 6.0 0.33 10.8 0.4 3.0 1 1 2 3 3 3 0 Casein Kinase 2 substrate Fib_alpha PF08702.10 OWF41966.1 - 0.034 14.4 0.4 0.49 10.6 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Med21 PF11221.8 OWF41966.1 - 0.048 13.9 0.0 3.7 7.8 0.0 2.8 1 1 2 3 3 3 0 Subunit 21 of Mediator complex FlgN PF05130.12 OWF41966.1 - 0.056 13.9 14.6 1.2 9.6 5.7 2.1 1 1 1 2 2 2 0 FlgN protein DUF632 PF04782.12 OWF41966.1 - 0.061 12.6 2.1 5.2 6.3 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF632) DUF5082 PF16888.5 OWF41966.1 - 0.067 13.5 0.0 17 5.7 0.0 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) SKA2 PF16740.5 OWF41966.1 - 0.071 12.9 6.7 0.84 9.4 1.5 2.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3450 PF11932.8 OWF41966.1 - 0.17 11.2 4.9 0.23 10.8 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Vps5 PF09325.10 OWF41966.1 - 0.2 11.2 12.2 1.8 8.1 3.0 2.4 1 1 2 3 3 3 0 Vps5 C terminal like ASL_C PF08328.11 OWF41966.1 - 0.21 11.7 17.4 1.9 8.6 1.5 3.7 1 1 3 4 4 4 0 Adenylosuccinate lyase C-terminal AAA_13 PF13166.6 OWF41966.1 - 0.24 10.0 0.8 0.27 9.8 0.8 1.1 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 OWF41966.1 - 0.24 12.0 6.2 11 6.8 0.7 3.3 1 1 2 3 3 3 0 SlyX SKA1 PF07160.12 OWF41966.1 - 0.27 11.1 1.2 6.7 6.5 0.3 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 YabA PF06156.13 OWF41966.1 - 0.3 11.7 1.1 21 5.8 0.1 2.6 1 1 1 2 2 2 0 Initiation control protein YabA HrpJ PF07201.11 OWF41966.1 - 0.31 11.3 3.2 3.1 8.1 0.3 2.2 1 1 1 2 2 2 0 HrpJ-like domain BLOC1_2 PF10046.9 OWF41966.1 - 0.36 11.2 9.4 21 5.5 9.3 2.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoA-II PF04711.13 OWF41966.1 - 0.58 10.4 4.6 2.4 8.4 0.1 3.5 1 1 2 3 3 3 0 Apolipoprotein A-II (ApoA-II) DUF3053 PF11254.8 OWF41966.1 - 0.66 9.5 9.5 3.1 7.3 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) FliD_N PF02465.18 OWF41966.1 - 0.74 10.5 13.1 5.2 7.8 1.9 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2935 PF11155.8 OWF41966.1 - 0.77 10.1 8.5 3 8.2 5.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF3130 PF11328.8 OWF41966.1 - 1.3 9.3 9.2 81 3.6 0.3 4.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3130 NPV_P10 PF05531.12 OWF41966.1 - 1.4 9.4 20.1 1.5e+02 3.0 3.1 3.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Med14 PF08638.11 OWF41966.1 - 1.6 8.1 14.1 3.6 6.9 4.5 2.3 1 1 1 2 2 2 0 Mediator complex subunit MED14 CENP-H PF05837.12 OWF41966.1 - 2.8 8.4 6.3 19 5.7 1.7 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) APG17 PF04108.12 OWF41966.1 - 3 6.9 8.0 1.9 7.5 5.5 1.7 1 1 1 2 2 2 0 Autophagy protein Apg17 FANCI_S4 PF14678.6 OWF41966.1 - 3.4 6.7 21.4 1.3 8.1 2.3 2.8 1 1 2 3 3 3 0 FANCI solenoid 4 FliH PF02108.16 OWF41966.1 - 7.6 6.6 13.4 1 9.4 1.9 2.6 1 1 1 2 2 2 0 Flagellar assembly protein FliH Baculo_PEP_C PF04513.12 OWF41967.1 - 1.7e-10 41.1 87.6 0.039 14.0 24.5 5.5 1 1 3 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 OWF41967.1 - 3.9e-05 23.5 50.4 0.02 14.7 29.7 2.6 1 1 1 2 2 2 2 Bacterial collagen, middle region CK2S PF15011.6 OWF41967.1 - 0.00023 21.1 15.0 0.28 11.0 1.1 3.8 1 1 3 4 4 4 2 Casein Kinase 2 substrate DUF5082 PF16888.5 OWF41967.1 - 0.00033 20.9 0.4 1.3 9.3 0.1 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) COG5 PF10392.9 OWF41967.1 - 0.0004 20.6 14.8 0.1 12.8 2.5 2.6 1 1 1 2 2 2 2 Golgi transport complex subunit 5 DUF1664 PF07889.12 OWF41967.1 - 0.00068 19.7 8.7 0.033 14.2 2.4 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Flagellar_rod PF05149.12 OWF41967.1 - 0.0015 18.0 0.6 0.16 11.4 0.1 2.1 1 1 1 2 2 2 1 Paraflagellar rod protein DUF632 PF04782.12 OWF41967.1 - 0.0021 17.4 2.8 2.1 7.6 0.1 3.6 1 1 3 4 4 4 1 Protein of unknown function (DUF632) FlgN PF05130.12 OWF41967.1 - 0.0027 18.2 26.3 0.011 16.3 11.5 2.1 1 1 1 2 2 2 2 FlgN protein BAR_3 PF16746.5 OWF41967.1 - 0.0034 17.1 9.0 0.88 9.2 0.7 3.2 1 1 2 3 3 3 2 BAR domain of APPL family Spc7 PF08317.11 OWF41967.1 - 0.0052 15.7 3.5 0.099 11.5 0.5 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein Lyase_8_N PF08124.11 OWF41967.1 - 0.0064 15.5 5.5 0.24 10.3 0.8 2.2 1 1 1 2 2 2 2 Polysaccharide lyase family 8, N terminal alpha-helical domain IKBKB_SDD PF18397.1 OWF41967.1 - 0.011 15.1 1.9 1.3 8.3 0.2 2.5 1 1 1 2 2 2 0 IQBAL scaffold dimerization domain DUF2463 PF09591.10 OWF41967.1 - 0.018 14.9 2.2 0.018 14.9 2.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2463) Fib_alpha PF08702.10 OWF41967.1 - 0.033 14.4 5.2 1.4 9.1 1.0 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 OWF41967.1 - 0.035 13.4 13.7 0.75 9.1 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SKA2 PF16740.5 OWF41967.1 - 0.043 13.6 14.5 0.81 9.5 1.9 3.7 1 1 3 4 4 4 0 Spindle and kinetochore-associated protein 2 Prefoldin_2 PF01920.20 OWF41967.1 - 0.051 13.5 1.2 2.9 7.9 0.3 3.3 1 1 2 3 3 3 0 Prefoldin subunit PI_PP_I PF18363.1 OWF41967.1 - 0.07 13.3 3.5 6.4 7.0 0.2 3.0 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain SKA1 PF07160.12 OWF41967.1 - 0.07 13.0 8.6 4.5 7.0 1.2 3.4 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF3584 PF12128.8 OWF41967.1 - 0.094 10.2 4.3 0.16 9.4 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 OWF41967.1 - 0.12 12.4 0.6 0.49 10.4 0.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 OWF41967.1 - 0.14 10.8 6.4 0.17 10.5 6.4 1.1 1 0 0 1 1 1 0 AAA domain DUF2408 PF10303.9 OWF41967.1 - 0.15 12.6 4.9 7.2 7.2 4.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) BAR PF03114.18 OWF41967.1 - 0.17 11.5 2.0 26 4.4 0.0 3.1 1 1 0 2 2 2 0 BAR domain SlyX PF04102.12 OWF41967.1 - 0.21 12.2 15.1 4.4 8.0 1.0 4.4 1 1 4 5 5 5 0 SlyX OEP PF02321.18 OWF41967.1 - 0.22 11.3 37.3 0.29 10.9 12.8 4.6 1 1 3 5 5 5 0 Outer membrane efflux protein YabA PF06156.13 OWF41967.1 - 0.25 12.0 7.8 2.2e+02 2.5 6.2 3.8 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 OWF41967.1 - 0.25 11.4 11.4 1.1 9.4 4.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Vps5 PF09325.10 OWF41967.1 - 0.27 10.8 23.5 2.8 7.4 3.8 3.3 1 1 3 4 4 4 0 Vps5 C terminal like BLOC1_2 PF10046.9 OWF41967.1 - 0.31 11.4 19.6 1.2 9.4 8.5 3.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 OWF41967.1 - 0.46 10.9 9.4 5.2 7.5 0.2 4.1 1 1 4 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IZUMO PF15005.6 OWF41967.1 - 0.54 10.8 8.2 1.1 9.8 1.3 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated MbeD_MobD PF04899.12 OWF41967.1 - 0.6 10.3 11.9 4.2 7.5 2.1 4.7 2 2 3 5 5 5 0 MbeD/MobD like DUF2935 PF11155.8 OWF41967.1 - 0.69 10.3 13.7 0.96 9.8 1.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) HAUS2 PF15003.6 OWF41967.1 - 0.72 9.5 11.6 1.4 8.6 2.9 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 ASL_C PF08328.11 OWF41967.1 - 0.87 9.7 20.9 0.56 10.3 1.4 4.4 1 1 4 5 5 5 0 Adenylosuccinate lyase C-terminal LPP PF04728.13 OWF41967.1 - 0.91 10.0 6.4 25 5.4 0.1 4.1 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Sigma54_activ_2 PF14532.6 OWF41967.1 - 0.93 9.6 14.5 4.2 7.5 0.9 3.2 2 1 1 3 3 3 0 Sigma-54 interaction domain FANCI_S4 PF14678.6 OWF41967.1 - 1.1 8.4 24.9 0.6 9.2 2.2 3.2 1 1 1 3 3 3 0 FANCI solenoid 4 NPV_P10 PF05531.12 OWF41967.1 - 2.2 8.8 30.8 1.9e+02 2.6 12.6 4.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SLX9 PF15341.6 OWF41967.1 - 3.5 8.0 5.1 3.1e+02 1.8 3.3 4.3 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Seryl_tRNA_N PF02403.22 OWF41967.1 - 3.7 7.8 8.7 12 6.2 0.5 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.11 OWF41967.1 - 4.1 7.7 8.6 1.6e+02 2.6 4.4 4.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 CENP-Q PF13094.6 OWF41967.1 - 8 6.6 8.3 15 5.8 1.5 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RhoGEF PF00621.20 OWF41968.1 - 6.8e-26 91.6 0.4 2.2e-25 90.0 0.4 1.9 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 OWF41968.1 - 2.1e-11 43.9 0.0 5.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 OWF41968.1 - 0.00019 21.3 0.6 0.00019 21.3 0.6 2.0 2 1 0 2 2 2 1 PH domain PH_5 PF15405.6 OWF41968.1 - 0.00022 21.3 3.3 0.0042 17.2 0.1 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 OWF41968.1 - 0.00075 20.0 0.0 0.0032 17.9 0.0 2.2 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 OWF41968.1 - 0.0054 17.0 0.0 0.02 15.2 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3439 PF11921.8 OWF41968.1 - 0.0072 16.3 0.2 0.019 14.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) WD40 PF00400.32 OWF41970.1 - 2.6e-67 221.1 18.1 1e-09 38.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF41970.1 - 1.7e-20 73.1 0.1 0.0032 17.7 0.0 6.3 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF41970.1 - 2.5e-11 43.8 0.2 0.00019 21.4 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF41970.1 - 4.6e-10 39.0 2.9 0.026 13.5 0.1 4.7 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 OWF41970.1 - 3.3e-06 25.9 0.4 0.0029 16.2 0.1 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain WD40_like PF17005.5 OWF41970.1 - 1.5e-05 24.5 0.1 4 6.7 0.0 4.7 3 1 1 5 5 5 2 WD40-like domain Frtz PF11768.8 OWF41970.1 - 0.012 13.9 0.0 0.41 8.9 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4988 PF16378.5 OWF41970.1 - 0.06 13.0 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function Proteasome_A_N PF10584.9 OWF41970.1 - 0.062 13.0 2.1 1.4 8.6 0.0 3.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TUDOR PF00567.24 OWF41971.1 - 3.7e-73 243.3 0.1 8.3e-25 87.2 0.0 3.9 3 0 0 3 3 3 3 Tudor domain DUF4537 PF15057.6 OWF41971.1 - 4.2e-06 26.8 0.1 0.49 10.4 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4537) zf-CCCH_4 PF18044.1 OWF41971.1 - 0.00078 19.2 3.2 0.0017 18.1 3.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OWF41971.1 - 0.00096 19.0 1.3 0.0018 18.1 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1325 PF07039.11 OWF41971.1 - 0.0013 18.9 0.1 1.3 9.1 0.0 3.5 3 0 0 3 3 3 1 SGF29 tudor-like domain Agenet PF05641.12 OWF41971.1 - 0.0013 19.1 0.9 0.29 11.7 0.2 3.4 3 0 0 3 3 3 1 Agenet domain zf-CCCH_2 PF14608.6 OWF41971.1 - 0.0016 18.8 4.1 0.0039 17.6 4.1 1.7 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 OWF41971.1 - 0.0042 17.1 6.8 0.0093 16.0 6.8 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 OWF41971.1 - 0.008 16.9 0.0 0.054 14.2 0.0 2.4 1 0 0 1 1 1 1 Torus domain LBR_tudor PF09465.10 OWF41971.1 - 0.016 15.0 0.4 0.21 11.4 0.3 2.8 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Tudor-knot PF11717.8 OWF41971.1 - 0.032 14.1 0.7 0.26 11.2 0.3 2.6 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-CCCH_3 PF15663.5 OWF41971.1 - 0.034 14.4 0.2 0.12 12.6 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger containing family Tudor_2 PF18104.1 OWF41971.1 - 0.12 12.1 0.1 28 4.5 0.0 2.9 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain PWWP PF00855.17 OWF41971.1 - 0.17 12.3 0.6 38 4.8 0.1 3.4 3 0 0 3 3 3 0 PWWP domain EABR PF12180.8 OWF41972.1 - 0.14 11.8 0.9 1e+02 2.6 0.0 3.9 4 0 0 4 4 4 0 TSG101 and ALIX binding domain of CEP55 DUF4064 PF13273.6 OWF41973.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Ribosomal_L2_C PF03947.18 OWF41974.1 - 3.6e-28 98.3 0.3 6.8e-28 97.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OWF41974.1 - 6.9e-18 64.4 0.7 7.7e-17 61.0 0.9 2.2 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain LSM PF01423.22 OWF41975.1 - 4.3e-19 68.0 0.2 5.1e-19 67.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain tRNA_edit PF04073.15 OWF41976.1 - 2.4e-10 40.5 11.0 42 4.2 0.0 14.0 4 3 13 18 18 18 1 Aminoacyl-tRNA editing domain Tox-HNH-HHH PF15637.6 OWF41976.1 - 0.51 10.5 7.2 1.4e+02 2.7 0.0 7.2 6 2 2 10 10 10 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF3713 PF12506.8 OWF41976.1 - 2.1 8.7 6.9 29 5.0 0.2 4.7 5 1 1 6 6 6 0 Protein of unknown function (DUF3713) Phage_TTP_11 PF16460.5 OWF41977.1 - 0.0037 17.1 0.0 3.3 7.5 0.0 3.0 1 1 2 3 3 3 2 Phage tail tube, TTP, lambda-like HTH_Tnp_IS1 PF12759.7 OWF41977.1 - 0.014 15.0 5.0 6.6 6.4 0.0 4.6 2 1 4 6 6 6 0 InsA C-terminal domain Gp-FAR-1 PF05823.12 OWF41977.1 - 0.073 13.4 0.0 2.5 8.5 0.0 2.4 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SspO PF08175.12 OWF41977.1 - 5.6 7.5 6.4 3.6 8.1 0.2 3.5 3 2 1 4 4 4 0 Small acid-soluble spore protein O family QCR10 PF09796.9 OWF41978.1 - 8.7e-08 32.1 38.2 0.79 9.8 0.7 8.8 2 1 6 8 8 8 7 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MerR-DNA-bind PF09278.11 OWF41978.1 - 0.005 17.3 0.6 66 4.2 0.0 4.3 1 1 4 5 5 5 0 MerR, DNA binding ZipA_C PF04354.13 OWF41978.1 - 0.071 13.0 5.8 12 5.7 2.3 3.7 1 1 2 3 3 3 0 ZipA, C-terminal FtsZ-binding domain Apolipoprotein PF01442.18 OWF41978.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain APC_15aa PF05972.11 OWF41978.1 - 0.88 10.0 7.9 2.8e+02 2.1 0.0 5.6 5 0 0 5 5 5 0 APC 15 residue motif NSP2_assoc PF14758.6 OWF41978.1 - 5.9 7.2 10.1 4.7 7.5 0.5 3.1 1 1 4 5 5 5 0 Non-essential region of nsp2 of arterivirus polyprotein Plexin_cytopl PF08337.12 OWF41979.1 - 8.2e-211 701.5 8.7 1.1e-210 701.1 8.7 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 OWF41979.1 - 4.8e-44 150.8 0.1 8.3e-44 150.1 0.1 1.4 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 OWF41979.1 - 4.9e-36 122.7 17.7 4.4e-10 39.5 1.3 6.6 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.25 OWF41979.1 - 3.3e-12 46.7 53.6 4.4e-09 36.7 14.8 3.8 3 0 0 3 3 3 2 Plexin repeat TIG_plexin PF17960.1 OWF41979.1 - 2.1e-11 43.7 5.7 1.3e-10 41.1 0.0 4.9 6 0 0 6 6 6 1 TIG domain TIG_2 PF18020.1 OWF41979.1 - 1.2e-08 35.4 0.0 9e-05 23.0 0.0 4.1 4 0 0 4 4 4 1 TIG domain found in plexin Peptidase_M56 PF05569.11 OWF41979.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 RIFIN PF02009.16 OWF41979.1 - 0.024 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 OWF41979.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OWF41979.1 - 0.19 11.5 3.1 0.4 10.5 3.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CD20 PF04103.15 OWF41979.1 - 0.71 10.0 3.0 0.52 10.4 0.0 2.3 2 0 0 2 2 2 0 CD20-like family Insulin_TMD PF17870.1 OWF41979.1 - 0.82 9.8 3.4 0.69 10.0 0.9 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF2678 PF10856.8 OWF41980.1 - 3.6e-42 143.0 0.6 4.1e-42 142.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF2417 PF10329.9 OWF41980.1 - 0.0012 18.3 2.9 0.0014 18.1 2.9 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2157 PF09925.9 OWF41980.1 - 0.012 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) EamA PF00892.20 OWF41980.1 - 0.018 15.2 5.5 0.026 14.7 5.5 1.2 1 0 0 1 1 1 0 EamA-like transporter family BaxI_1 PF12811.7 OWF41980.1 - 0.047 13.2 2.2 0.084 12.4 2.2 1.5 1 1 0 1 1 1 0 Bax inhibitor 1 like BPD_transp_2 PF02653.16 OWF41980.1 - 0.14 11.3 6.3 3.1 6.9 0.1 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component DUF2070 PF09843.9 OWF41980.1 - 0.19 9.9 1.5 0.23 9.7 1.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3290 PF11694.8 OWF41980.1 - 0.93 9.5 5.0 0.21 11.6 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) E1-E2_ATPase PF00122.20 OWF41980.1 - 1.6 8.2 4.6 1.9 8.0 3.7 1.5 1 1 1 2 2 2 0 E1-E2 ATPase Myb_DNA-binding PF00249.31 OWF41981.1 - 2.5e-22 78.8 8.3 2.7e-10 40.3 0.2 4.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF41981.1 - 1.8e-13 50.5 11.3 2.5e-08 34.0 0.0 4.0 3 1 1 4 4 4 3 Myb-like DNA-binding domain AIG1 PF04548.16 OWF41981.1 - 0.086 12.2 0.9 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family ATP-grasp_2 PF08442.10 OWF41982.1 - 2.4e-73 246.0 3.0 3.5e-73 245.5 3.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OWF41982.1 - 3.3e-24 85.4 0.3 8.3e-24 84.2 0.3 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OWF41982.1 - 2.9e-11 43.3 0.2 4.2e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_bind PF16114.5 OWF41982.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding GARS_A PF01071.19 OWF41982.1 - 0.0017 18.2 0.1 0.0036 17.1 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MHC_II_beta PF00969.19 OWF41983.1 - 0.0021 18.1 2.1 73 3.6 0.0 5.3 1 1 4 6 6 6 0 Class II histocompatibility antigen, beta domain Ephrin_lbd PF01404.19 OWF41983.1 - 0.082 12.9 0.4 9.9 6.2 0.1 3.3 1 1 2 3 3 3 0 Ephrin receptor ligand binding domain FTCD_C PF04961.12 OWF41983.1 - 0.8 9.4 9.2 11 5.8 0.2 3.4 1 1 2 3 3 3 0 Formiminotransferase-cyclodeaminase Glyco_hydro_59M PF17387.2 OWF41983.1 - 0.87 9.8 7.0 14 5.9 0.1 4.6 2 1 4 6 6 6 0 Glycosyl hydrolase family 59 central domain DUF4573 PF15140.6 OWF41984.1 - 7.1e-07 29.2 0.0 0.0014 18.5 0.0 2.8 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) DUF630 PF04783.12 OWF41984.1 - 3.9e-06 26.9 5.0 42 4.4 0.0 8.1 6 1 2 8 8 8 1 Protein of unknown function (DUF630) MHC_II_beta PF00969.19 OWF41984.1 - 0.0021 18.1 16.2 88 3.3 0.0 11.2 5 2 8 13 13 13 0 Class II histocompatibility antigen, beta domain Ephrin_lbd PF01404.19 OWF41984.1 - 0.0096 16.0 2.7 60 3.6 0.0 5.8 3 2 3 6 6 6 0 Ephrin receptor ligand binding domain Transglut_core PF01841.19 OWF41985.1 - 5.6e-07 30.0 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily MlaC PF05494.12 OWF41985.1 - 0.026 14.3 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 MlaC protein SHOCT PF09851.9 OWF41985.1 - 0.046 13.5 0.3 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Short C-terminal domain Hydrolase_6 PF13344.6 OWF41986.1 - 1.3e-19 70.1 0.0 2.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OWF41986.1 - 1e-05 25.5 0.0 0.00052 20.0 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Isy1 PF06246.12 OWF41987.1 - 7.1e-94 314.1 16.6 8.4e-94 313.9 16.6 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF4094 PF13334.6 OWF41987.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) CSRNP_N PF16019.5 OWF41987.1 - 1.1 9.1 4.4 2.1 8.2 4.4 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF740 PF05340.12 OWF41987.1 - 2.6 6.7 8.7 3.5 6.2 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Brix PF04427.18 OWF41988.1 - 1.2e-32 113.6 0.6 1.6e-32 113.2 0.6 1.1 1 0 0 1 1 1 1 Brix domain BORCS6 PF10157.9 OWF41989.1 - 5.8e-49 166.2 3.0 5.8e-49 166.2 3.0 1.8 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 6 CLP1_P PF16575.5 OWF41990.1 - 3.4e-38 131.3 0.0 2.7e-37 128.4 0.0 2.3 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 OWF41990.1 - 0.048 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 GCV_T PF01571.21 OWF41991.1 - 2.9e-86 289.0 0.0 3.4e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OWF41991.1 - 1.6e-08 34.3 0.0 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain RCC1 PF00415.18 OWF41992.1 - 2.8e-65 216.8 26.1 2.3e-13 50.5 0.9 9.1 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF41992.1 - 3.1e-36 122.4 43.3 4.5e-07 29.5 2.2 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat TPR_12 PF13424.6 OWF41992.1 - 0.11 12.8 0.1 0.67 10.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP90 PF00183.18 OWF41993.1 - 1.1e-222 740.5 28.9 1.1e-222 740.5 28.9 1.7 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 OWF41993.1 - 8.4e-14 52.0 0.2 1.6e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OWF41993.1 - 4.5e-11 42.7 0.4 1.2e-10 41.3 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L10 PF00466.20 OWF41993.1 - 0.082 13.1 3.7 1.9 8.7 0.2 3.1 3 0 0 3 3 3 0 Ribosomal protein L10 NADPH_Ox PF08414.10 OWF41993.1 - 0.67 10.3 4.0 13 6.1 0.2 4.1 4 0 0 4 4 4 0 Respiratory burst NADPH oxidase TPR_12 PF13424.6 OWF41994.1 - 5.2e-13 49.1 6.3 0.00016 21.9 0.3 4.4 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OWF41994.1 - 6.1e-08 32.3 1.6 0.014 15.2 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 OWF41994.1 - 2.4e-06 27.6 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OWF41994.1 - 3.4e-06 27.5 0.0 8.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF4062 PF13271.6 OWF41994.1 - 6.9e-06 26.3 0.0 7.8e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) AAA_22 PF13401.6 OWF41994.1 - 0.005 17.1 0.4 0.057 13.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OWF41994.1 - 0.023 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gemini_AL1_M PF08283.11 OWF41994.1 - 0.034 14.2 1.0 0.38 10.9 0.1 3.1 3 0 0 3 3 3 0 Geminivirus rep protein central domain Helicase_RecD PF05127.14 OWF41994.1 - 0.076 12.9 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Helicase TPR_14 PF13428.6 OWF41994.1 - 0.12 13.3 0.3 13 6.9 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF41994.1 - 0.19 11.1 0.2 0.41 10.0 0.2 1.5 1 0 0 1 1 1 0 MalT-like TPR region TPR_8 PF13181.6 OWF41994.1 - 0.96 9.8 2.3 1e+02 3.5 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF563 PF04577.14 OWF41995.1 - 5e-25 88.9 0.2 7.7e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) GDNF PF02351.16 OWF41995.1 - 0.39 11.7 6.0 0.35 11.9 3.4 2.2 2 0 0 2 2 2 0 GDNF/GAS1 domain Hormone_recep PF00104.30 OWF41996.1 - 3e-43 147.8 3.8 3e-43 147.8 3.8 2.3 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF41996.1 - 3.2e-32 110.8 11.9 5.8e-32 110.0 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) NAPRTase_N PF17767.1 OWF41996.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF2345 PF10106.9 OWF41997.1 - 1.5e-07 31.4 0.3 0.039 13.8 0.1 3.3 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2345) DDE_Tnp_IS1 PF03400.13 OWF41997.1 - 0.026 14.8 0.8 28 5.0 0.0 4.0 1 1 2 4 4 4 0 IS1 transposase MoaC PF01967.21 OWF41997.1 - 0.06 13.4 1.2 64 3.6 0.1 3.8 1 1 2 4 4 4 0 MoaC family Arf PF00025.21 OWF41999.1 - 2.2e-76 255.2 0.1 2.5e-76 255.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF41999.1 - 4.3e-15 56.0 0.1 6e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OWF41999.1 - 2.8e-14 53.0 0.0 3.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OWF41999.1 - 1.4e-13 50.8 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OWF41999.1 - 2.6e-13 49.9 1.8 5.7e-10 38.9 0.5 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OWF41999.1 - 8e-12 45.0 0.0 9.1e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF41999.1 - 3.9e-07 30.2 0.3 2.8e-06 27.4 0.1 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OWF41999.1 - 0.0057 16.0 0.3 0.014 14.7 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.19 OWF41999.1 - 0.12 12.0 0.4 0.73 9.4 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 7tm_1 PF00001.21 OWF42000.1 - 9.3e-17 61.2 17.5 9.3e-17 61.2 17.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF42000.1 - 1.8e-06 27.6 22.6 5.7e-06 25.9 22.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF42000.1 - 3.6e-06 26.8 16.5 3.6e-06 26.8 16.5 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CbtB PF09489.10 OWF42000.1 - 0.38 10.9 1.2 1.5 9.0 0.2 2.4 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF2107 PF09880.9 OWF42000.1 - 2 8.6 9.2 1.9 8.6 0.2 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) CBM_14 PF01607.24 OWF42002.1 - 1e-12 48.0 11.4 4.7e-08 33.1 0.3 5.0 7 0 0 7 7 7 2 Chitin binding Peritrophin-A domain TSP_1 PF00090.19 OWF42002.1 - 1.5e-08 34.7 58.2 8.2e-05 22.7 12.6 5.7 5 3 0 5 5 5 3 Thrombospondin type 1 domain CBM_14 PF01607.24 OWF42003.1 - 1.9e-32 111.1 37.3 6e-10 39.1 7.5 4.7 3 1 0 4 4 4 4 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 OWF42003.1 - 5.6 7.0 9.7 0.91 9.6 0.3 3.7 3 2 0 3 3 3 0 Carbohydrate binding domain (family 19) Cu-oxidase_3 PF07732.15 OWF42004.1 - 7.6e-41 138.9 1.8 5.3e-39 132.9 0.6 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF42004.1 - 8e-35 119.6 8.2 9.3e-30 103.1 0.1 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF42004.1 - 1.1e-33 116.7 0.2 3.2e-30 105.4 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Rax2 PF12768.7 OWF42007.1 - 0.097 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity MRAP PF15183.6 OWF42007.1 - 0.12 12.4 0.1 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF2207 PF09972.9 OWF42007.1 - 0.14 10.9 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 OWF42007.1 - 0.17 11.9 2.0 0.31 11.0 2.0 1.4 1 0 0 1 1 1 0 Syndecan domain Rsa3 PF14615.6 OWF42008.1 - 0.12 12.0 0.1 0.51 9.9 0.1 2.1 2 0 0 2 2 2 0 Ribosome-assembly protein 3 Forkhead PF00250.18 OWF42009.1 - 9.2e-33 112.4 0.1 1.8e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 OWF42009.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family FYVE PF01363.21 OWF42010.1 - 1.6e-19 69.8 13.2 6.1e-19 67.9 13.2 2.1 1 0 0 1 1 1 1 FYVE zinc finger zf-met PF12874.7 OWF42010.1 - 2.1e-05 24.8 0.8 0.078 13.4 0.0 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Tropomyosin PF00261.20 OWF42010.1 - 0.00016 21.2 67.1 0.00064 19.2 23.2 10.2 2 1 8 10 10 7 3 Tropomyosin DUF2730 PF10805.8 OWF42010.1 - 0.00021 21.3 0.7 0.00021 21.3 0.7 16.1 7 4 11 19 19 19 3 Protein of unknown function (DUF2730) zf-C2H2_jaz PF12171.8 OWF42010.1 - 0.0023 18.2 7.3 1 9.7 0.0 4.9 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding DUF1664 PF07889.12 OWF42010.1 - 0.0025 17.8 3.8 0.0025 17.8 3.8 15.5 2 1 15 19 19 19 4 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 OWF42010.1 - 0.0025 18.0 21.8 0.0025 18.0 21.8 14.5 1 1 14 15 15 12 2 JNK_SAPK-associated protein-1 Uds1 PF15456.6 OWF42010.1 - 0.0027 17.9 13.6 0.0027 17.9 13.6 13.8 2 2 10 14 14 9 1 Up-regulated During Septation zf-C2H2_4 PF13894.6 OWF42010.1 - 0.0037 18.0 1.3 0.048 14.5 0.1 4.3 4 0 0 4 4 3 2 C2H2-type zinc finger Spc7 PF08317.11 OWF42010.1 - 0.0089 14.9 283.2 0.28 10.0 29.1 12.0 1 1 11 12 12 12 8 Spc7 kinetochore protein zf-C2H2 PF00096.26 OWF42010.1 - 0.092 13.2 0.1 0.092 13.2 0.1 4.5 6 0 0 6 6 4 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 OWF42010.1 - 0.11 12.1 0.1 0.11 12.1 0.1 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 OWF42010.1 - 0.24 11.2 4.9 7.2 6.5 0.1 3.8 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) Elf1 PF05129.13 OWF42010.1 - 4.4 7.4 12.4 0.53 10.4 4.6 3.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf_C2H2_ZHX PF18387.1 OWF42010.1 - 5.3 6.8 8.3 13 5.5 0.0 4.1 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Pyr_redox_2 PF07992.14 OWF42011.1 - 2.5e-71 240.3 7.2 3.1e-71 240.0 4.5 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OWF42011.1 - 6.7e-41 139.0 0.5 3.2e-40 136.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OWF42011.1 - 4.3e-19 68.9 8.9 7.2e-17 61.7 2.1 3.2 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF42011.1 - 3.3e-10 39.7 4.4 2.7e-07 30.1 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF42011.1 - 5.7e-10 39.1 9.3 2.6e-09 36.9 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OWF42011.1 - 1.3e-07 31.1 6.4 1.7e-07 30.7 0.4 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OWF42011.1 - 2.2e-07 31.0 1.6 0.001 19.2 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OWF42011.1 - 1e-06 28.2 5.0 0.054 12.7 0.2 3.2 3 0 0 3 3 3 3 FAD binding domain GIDA PF01134.22 OWF42011.1 - 1.2e-06 27.9 10.0 6.9e-06 25.4 4.0 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 OWF42011.1 - 6.2e-05 22.3 1.0 0.14 11.3 0.2 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OWF42011.1 - 7.8e-05 21.5 9.3 0.00096 18.0 0.5 3.6 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OWF42011.1 - 0.00027 20.3 5.1 0.038 13.3 0.7 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OWF42011.1 - 0.0029 16.9 1.2 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 OWF42011.1 - 0.01 15.5 2.8 0.72 9.4 0.3 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 OWF42011.1 - 0.012 15.0 0.4 3.8 6.8 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OWF42011.1 - 2.6 7.0 4.3 3.7 6.5 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 OWF42011.1 - 8.4 5.9 16.9 2.2 7.8 0.2 3.8 3 1 1 4 4 4 0 FAD dependent oxidoreductase O-FucT PF10250.9 OWF42012.1 - 0.0032 17.2 0.2 0.0075 16.0 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 OWF42012.1 - 0.0059 15.9 0.1 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 11 LPD15 PF18828.1 OWF42012.1 - 0.017 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 V_cholerae_RfbT PF05575.11 OWF42012.1 - 0.055 12.7 0.2 0.088 12.1 0.2 1.2 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein cIII PF08134.11 OWF42012.1 - 0.63 9.8 0.1 0.63 9.8 0.1 1.9 2 0 0 2 2 2 0 cIII protein family O-FucT PF10250.9 OWF42013.1 - 0.0046 16.7 0.2 0.01 15.5 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 OWF42013.1 - 0.0052 16.1 0.1 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 11 LPD15 PF18828.1 OWF42013.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 V_cholerae_RfbT PF05575.11 OWF42013.1 - 0.04 13.2 0.3 0.066 12.5 0.3 1.2 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein cIII PF08134.11 OWF42013.1 - 0.73 9.6 0.1 0.73 9.6 0.1 1.9 2 0 0 2 2 2 0 cIII protein family Glyco_transf_11 PF01531.16 OWF42014.1 - 0.038 13.2 0.2 0.046 12.9 0.2 1.3 1 1 0 1 1 1 0 Glycosyl transferase family 11 O-FucT PF10250.9 OWF42015.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 OWF42015.1 - 0.032 13.4 0.3 0.04 13.1 0.3 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 11 NodZ PF05830.11 OWF42015.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) VEFS-Box PF09733.9 OWF42015.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Galactosyl_T PF01762.21 OWF42016.1 - 5.8e-38 130.7 1.8 6.4e-38 130.5 1.8 1.0 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 OWF42017.1 - 1.2e-49 168.8 3.3 2.4e-49 167.8 3.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase HLH PF00010.26 OWF42018.1 - 3.2e-15 55.8 1.1 6.2e-15 54.9 1.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF42018.1 - 0.00086 19.5 0.1 0.0028 17.8 0.0 1.9 2 0 0 2 2 2 1 Hairy Orange Translin PF01997.16 OWF42018.1 - 0.017 15.1 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Translin family ACDC PF14733.6 OWF42018.1 - 0.16 12.3 0.4 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 AP2-coincident C-terminal TruD PF01142.18 OWF42019.1 - 1.3e-80 271.3 0.0 1.8e-74 251.1 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) LRR_6 PF13516.6 OWF42020.1 - 3.5e-22 76.5 37.9 0.034 14.2 0.1 12.2 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 OWF42020.1 - 3.2e-16 59.2 27.1 0.0039 17.6 0.0 7.4 3 3 4 8 8 8 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OWF42020.1 - 1.5e-09 37.6 0.1 5e-09 35.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF42020.1 - 4.5e-09 36.0 0.0 1.4e-07 31.2 0.0 3.0 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 OWF42020.1 - 6.3e-08 32.1 23.1 11 7.0 0.0 10.2 9 1 2 11 11 11 3 Leucine Rich Repeat LRR_8 PF13855.6 OWF42020.1 - 7.4e-06 25.6 26.4 0.7 9.7 0.6 7.5 3 3 3 7 7 7 5 Leucine rich repeat SAM_Ste50p PF09235.10 OWF42020.1 - 0.0048 17.1 1.0 0.68 10.2 0.1 3.9 3 0 0 3 3 3 1 Ste50p, sterile alpha motif zf-C4 PF00105.18 OWF42021.1 - 1.1e-29 102.6 12.9 3.5e-29 101.1 12.9 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF42021.1 - 1.2e-09 38.1 2.4 2.6e-09 37.0 2.4 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor UBA PF00627.31 OWF42022.1 - 5.5e-17 61.3 3.3 5.1e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 UBA/TS-N domain Ubiquitin_5 PF18037.1 OWF42022.1 - 3.6e-16 59.3 0.1 1.6e-15 57.2 0.1 2.2 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 OWF42022.1 - 2.6e-05 23.9 1.1 0.0001 22.0 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin family HOIP-UBA PF16678.5 OWF42022.1 - 0.00017 21.6 6.1 0.28 11.2 1.2 3.6 2 1 0 3 3 3 2 HOIP UBA domain pair UBA_4 PF14555.6 OWF42022.1 - 0.004 16.9 0.3 0.33 10.8 0.0 3.3 3 0 0 3 3 3 1 UBA-like domain CUE PF02845.16 OWF42022.1 - 0.0043 16.7 0.4 1.6 8.5 0.0 3.6 3 0 0 3 3 3 1 CUE domain DUF2407 PF10302.9 OWF42022.1 - 0.0098 16.4 1.4 0.042 14.4 0.1 2.5 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain WYL_3 PF18488.1 OWF42022.1 - 0.017 15.5 0.2 0.26 11.7 0.1 2.6 2 0 0 2 2 2 0 WYL domain YfdX PF10938.8 OWF42022.1 - 0.079 12.9 5.7 0.082 12.8 0.6 2.9 3 0 0 3 3 3 0 YfdX protein Rad60-SLD_2 PF13881.6 OWF42022.1 - 0.12 12.4 0.6 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TPR_2 PF07719.17 OWF42022.1 - 0.53 10.5 4.2 24 5.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF42022.1 - 0.86 9.9 4.9 2.6 8.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 OWF42023.1 - 7.4e-27 92.5 68.4 1.3e-09 38.0 1.0 10.0 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2 PF00096.26 OWF42023.1 - 4.6e-24 83.5 63.4 7.9e-05 22.9 2.2 8.9 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF42023.1 - 9.1e-17 60.3 61.9 0.0015 19.2 0.6 8.7 9 0 0 9 9 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF42023.1 - 8.6e-08 32.3 34.3 0.12 12.7 0.2 8.2 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF42023.1 - 0.00029 21.1 41.0 0.53 10.8 1.1 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type Elf1 PF05129.13 OWF42023.1 - 0.0093 16.0 4.9 0.0093 16.0 4.9 5.3 3 1 3 6 6 4 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 OWF42023.1 - 0.0097 16.0 26.0 1.5 9.0 0.4 5.3 4 1 1 5 5 5 3 Zinc ribbon domain zf-RAG1 PF10426.9 OWF42023.1 - 0.079 13.1 0.5 0.22 11.7 0.5 1.8 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-H2C2_5 PF13909.6 OWF42023.1 - 0.12 12.2 0.1 0.12 12.2 0.1 6.2 6 0 0 6 6 5 0 C2H2-type zinc-finger domain GAGA PF09237.11 OWF42023.1 - 0.12 12.1 11.1 1 9.2 0.9 4.0 2 1 0 3 3 3 0 GAGA factor BolA PF01722.18 OWF42023.1 - 0.58 10.5 6.2 18 5.7 0.2 3.8 3 0 0 3 3 3 0 BolA-like protein zinc_ribbon_9 PF14369.6 OWF42023.1 - 1 9.6 20.6 6.3 7.1 0.1 6.0 6 0 0 6 6 6 0 zinc-ribbon zf-Di19 PF05605.12 OWF42023.1 - 1.5 9.2 34.4 0.27 11.6 1.9 4.7 2 1 5 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 OWF42023.1 - 3.2 8.4 31.3 1.9 9.1 0.6 6.3 4 2 2 6 6 5 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 OWF42023.1 - 7.8 7.3 23.2 15 6.4 0.5 4.6 1 1 2 4 4 4 0 zinc-ribbon family Mut7-C PF01927.16 OWF42023.1 - 8 6.6 15.0 1.3 9.2 1.2 3.5 1 1 2 3 3 3 0 Mut7-C RNAse domain zf-C2H2_2 PF12756.7 OWF42023.1 - 8.1 6.9 33.6 8.6 6.8 0.1 6.5 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) DUF4428 PF14471.6 OWF42023.1 - 8.3 6.4 13.3 1.5 8.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Il2rg PF15874.5 OWF42024.1 - 4.8e-24 84.4 0.2 6.4e-24 84.0 0.2 1.2 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain DUF2982 PF11201.8 OWF42024.1 - 0.03 13.9 0.0 0.055 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2982) DUF1416 PF07210.12 OWF42024.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) FA_desaturase PF00487.24 OWF42025.1 - 1.8e-30 106.6 17.7 3.8e-30 105.6 17.7 1.6 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OWF42025.1 - 6.1e-23 80.8 0.0 1.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cytokin_check_N PF10407.9 OWF42025.1 - 0.48 10.4 2.3 2.2 8.3 0.0 2.6 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus zf-C4 PF00105.18 OWF42026.1 - 1.4e-30 105.5 15.3 1.4e-30 105.5 15.3 2.1 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF42026.1 - 9e-24 84.2 0.0 2.3e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF533 PF04391.12 OWF42026.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) 7tm_1 PF00001.21 OWF42027.1 - 3.9e-23 82.1 18.9 5.2e-23 81.7 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF42027.1 - 3.4e-16 59.4 21.4 3.5e-15 56.1 21.4 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Aminotran_1_2 PF00155.21 OWF42028.1 - 3.3e-35 121.9 0.0 4.2e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OWF42028.1 - 0.01 15.1 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase DUF2004 PF09406.10 OWF42029.1 - 0.047 14.0 1.7 0.054 13.8 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) SGS PF05002.15 OWF42030.1 - 0.017 15.2 8.7 0.059 13.5 2.6 2.4 1 1 1 2 2 2 0 SGS domain Mucin-like PF16058.5 OWF42030.1 - 0.042 13.9 3.4 0.14 12.2 3.4 1.8 1 1 0 1 1 1 0 Mucin-like KRAB PF01352.27 OWF42030.1 - 0.22 11.2 5.6 2.9 7.6 0.3 3.6 2 1 1 3 3 3 0 KRAB box DUF2004 PF09406.10 OWF42030.1 - 1.9 8.8 16.1 7.9 6.9 1.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2004) YqeY PF09424.10 OWF42030.1 - 6.3 6.9 8.7 6.9 6.7 0.5 3.1 1 1 3 4 4 4 0 Yqey-like protein Molybdop_Fe4S4 PF04879.16 OWF42031.1 - 0.19 11.8 5.0 49 4.0 5.0 3.1 1 1 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain DUF2004 PF09406.10 OWF42031.1 - 1.7 9.0 8.7 17 5.8 8.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2004) Drf_FH1 PF06346.12 OWF42032.1 - 0.051 13.3 14.4 0.53 10.0 2.3 3.9 2 2 2 4 4 4 0 Formin Homology Region 1 DUF1295 PF06966.12 OWF42032.1 - 3.1 7.2 7.6 27 4.2 0.0 5.2 5 2 0 5 5 5 0 Protein of unknown function (DUF1295) RRM_1 PF00076.22 OWF42033.1 - 2.8e-21 75.1 0.0 7.1e-09 35.4 0.0 5.2 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1c PF00749.21 OWF42033.1 - 0.027 13.4 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF3123 PF11321.8 OWF42034.1 - 0.34 11.6 6.9 48 4.7 6.9 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) SRCR PF00530.18 OWF42034.1 - 0.71 10.4 4.2 64 4.1 4.2 2.7 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain CBM_14 PF01607.24 OWF42034.1 - 9.6 6.5 11.4 1.1e+02 3.1 0.0 4.8 1 1 4 5 5 5 0 Chitin binding Peritrophin-A domain CPBP PF02517.16 OWF42035.1 - 2.1e-10 40.8 10.8 1e-09 38.6 10.6 2.1 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Pro_isomerase PF00160.21 OWF42036.1 - 2e-50 171.1 0.1 5.2e-50 169.8 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 OWF42036.1 - 3.3e-07 29.9 9.1 4.2e-07 29.6 0.5 2.8 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 OWF42036.1 - 0.0038 17.3 0.0 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 OWF42036.1 - 0.037 14.2 0.0 0.15 12.2 0.0 2.0 1 1 1 2 2 2 0 U-box domain zf-Nse PF11789.8 OWF42036.1 - 0.1 12.4 0.8 0.46 10.3 0.8 2.1 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Peptidase_M41 PF01434.18 OWF42037.1 - 3.3e-66 222.8 0.1 5.3e-66 222.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OWF42037.1 - 1.3e-43 148.5 0.0 2.8e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF42037.1 - 4.4e-13 48.8 0.2 1.6e-12 47.0 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OWF42037.1 - 9.5e-10 38.8 0.2 2.8e-09 37.3 0.2 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 OWF42037.1 - 0.00077 19.7 0.1 0.18 12.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OWF42037.1 - 0.0011 19.1 0.0 0.0036 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OWF42037.1 - 0.0031 16.8 0.1 0.0077 15.5 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 OWF42037.1 - 0.0069 16.1 0.0 0.023 14.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 OWF42037.1 - 0.011 16.2 0.5 0.078 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OWF42037.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 OWF42037.1 - 0.015 15.8 0.2 1.1 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OWF42037.1 - 0.016 15.2 1.1 0.08 12.9 0.2 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF42037.1 - 0.022 15.1 0.2 0.29 11.5 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 OWF42037.1 - 0.042 13.2 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OWF42037.1 - 0.05 13.6 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sec7 PF01369.20 OWF42037.1 - 0.13 11.9 0.1 0.35 10.5 0.1 1.7 1 0 0 1 1 1 0 Sec7 domain DUF1514 PF07438.11 OWF42037.1 - 0.16 11.8 0.0 0.6 10.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF2615 PF11027.8 OWF42038.1 - 2.1e-05 24.6 0.1 3.8e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) TMEM51 PF15345.6 OWF42038.1 - 0.00046 20.1 5.0 0.0038 17.1 0.0 2.3 1 1 1 2 2 2 1 Transmembrane protein 51 EphA2_TM PF14575.6 OWF42038.1 - 0.0015 19.4 0.0 0.0029 18.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF42038.1 - 0.0021 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family PMP1_2 PF08114.11 OWF42038.1 - 0.025 14.3 1.8 0.042 13.6 1.8 1.3 1 0 0 1 1 1 0 ATPase proteolipid family DUF1180 PF06679.12 OWF42038.1 - 0.035 14.5 0.0 0.3 11.5 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) SKG6 PF08693.10 OWF42038.1 - 0.038 13.4 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SARAF PF06682.12 OWF42038.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SCIMP PF15050.6 OWF42038.1 - 0.05 14.1 0.2 0.1 13.0 0.0 1.6 2 0 0 2 2 2 0 SCIMP protein Oxidored_q2 PF00420.24 OWF42038.1 - 0.051 13.2 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Neur_chan_memb PF02932.16 OWF42038.1 - 0.063 13.3 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RCR PF12273.8 OWF42038.1 - 0.096 13.3 1.6 0.4 11.4 1.6 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3123 PF11321.8 OWF42038.1 - 0.22 12.2 1.7 1.6 9.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) CUB PF00431.20 OWF42039.1 - 3.8e-11 43.3 0.0 6.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain 7tm_1 PF00001.21 OWF42040.1 - 5.7e-21 75.0 22.0 7e-21 74.7 22.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF42040.1 - 2e-13 50.3 22.5 7e-13 48.5 22.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Pentapeptide_4 PF13599.6 OWF42041.1 - 4.6e-24 84.4 40.3 0.23 11.7 0.6 11.6 1 1 11 12 12 12 12 Pentapeptide repeats (9 copies) Peptidase_S8 PF00082.22 OWF42042.1 - 3.8e-39 134.7 0.3 7.2e-39 133.8 0.3 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OWF42042.1 - 3.4e-21 75.0 0.0 7.1e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OWF42042.1 - 7e-11 42.7 0.9 7e-11 42.7 0.9 2.2 2 0 0 2 2 2 1 Peptidase S8 pro-domain Desulfoferrodox PF01880.18 OWF42042.1 - 0.061 13.9 0.1 0.17 12.5 0.1 1.7 1 0 0 1 1 1 0 Desulfoferrodoxin BLACT_WH PF17778.1 OWF42042.1 - 0.12 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain PRP1_N PF06424.12 OWF42042.1 - 1.2 9.5 9.8 2.6 8.4 9.8 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF4404 PF14357.6 OWF42042.1 - 1.2 9.8 7.2 16 6.2 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMEM138 PF14935.6 OWF42043.1 - 6.6e-47 159.1 6.7 6.6e-47 159.1 6.7 1.8 2 0 0 2 2 2 1 Transmembrane protein 138 GCP_C_terminal PF04130.13 OWF42044.1 - 1e-81 274.8 14.4 1.9e-81 273.9 14.4 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OWF42044.1 - 2.1e-78 264.1 0.5 2.1e-78 264.1 0.5 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Reeler PF02014.16 OWF42045.1 - 3.8e-10 40.6 1.1 5.6e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Reeler domain Peptidase_M13_N PF05649.13 OWF42046.1 - 0.019 14.6 16.1 3.5 7.2 0.7 4.5 1 1 3 4 4 4 0 Peptidase family M13 AKAP95 PF04988.12 OWF42046.1 - 0.054 13.7 7.7 4.9 7.4 0.7 3.5 1 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF2267 PF10025.9 OWF42046.1 - 0.11 12.8 19.3 0.56 10.5 3.4 3.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2267) CBP_BcsF PF11120.8 OWF42046.1 - 6.2 7.0 60.2 0.77 9.9 3.3 8.6 1 1 10 11 11 11 0 Cellulose biosynthesis protein BcsF Proteasome PF00227.26 OWF42047.1 - 1.8e-52 177.6 0.0 2.2e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OWF42047.1 - 1.9e-13 49.8 0.0 4.2e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF727 PF05303.12 OWF42048.1 - 1.5e-29 102.1 0.1 2.2e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) DUF1848 PF08902.11 OWF42048.1 - 0.029 14.1 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Glyco_hydro_47 PF01532.20 OWF42049.1 - 1.9e-153 511.6 0.2 3e-153 511.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 OWF42049.1 - 0.00086 18.5 0.1 0.19 10.8 0.1 2.7 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 DUF1978 PF09321.10 OWF42049.1 - 0.0009 18.6 7.0 0.011 15.1 7.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1978) Glyco_hydro_76 PF03663.14 OWF42049.1 - 0.0012 18.4 3.2 0.63 9.5 0.0 4.0 3 1 0 4 4 4 1 Glycosyl hydrolase family 76 O-FucT PF10250.9 OWF42049.1 - 0.081 12.6 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase DUF4894 PF16235.5 OWF42050.1 - 2.4e-05 24.7 58.4 14 6.0 1.9 11.3 1 1 5 6 6 6 3 Domain of unknown function (DUF4894) DUF1372 PF07116.11 OWF42051.1 - 0.00014 22.0 38.4 1.4 9.1 3.0 6.1 1 1 6 7 7 7 6 Protein of unknown function (DUF1372) DUF4894 PF16235.5 OWF42051.1 - 0.0058 17.0 10.9 11 6.4 0.3 4.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4894) DUF4649 PF15507.6 OWF42051.1 - 0.11 12.4 12.0 9.3 6.3 0.2 5.8 1 1 6 7 7 7 0 Domain of unknown function (DUF4649) FDX-ACB PF03147.14 OWF42051.1 - 1.2 9.6 5.5 12 6.5 0.2 3.5 1 1 2 3 3 3 0 Ferredoxin-fold anticodon binding domain Lysyl_oxidase PF01186.17 OWF42051.1 - 1.3 8.7 18.1 7.6 6.1 1.8 3.9 1 1 3 4 4 4 0 Lysyl oxidase Hexokinase_2 PF03727.16 OWF42053.1 - 1.3e-62 211.4 0.0 1.7e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OWF42053.1 - 2.3e-30 106.0 0.0 3.7e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1731 PF08338.11 OWF42053.1 - 0.064 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Pentapeptide_4 PF13599.6 OWF42054.1 - 8.6e-06 25.8 30.0 1.1e+02 3.0 0.2 13.7 1 1 24 25 25 25 6 Pentapeptide repeats (9 copies) Exo_endo_phos PF03372.23 OWF42055.1 - 1.6e-19 70.4 0.0 1.9e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OWF42055.1 - 0.013 15.3 0.0 0.084 12.7 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Ank_2 PF12796.7 OWF42056.1 - 1.2e-23 83.5 3.6 1.5e-10 41.5 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF42056.1 - 1.9e-20 70.7 5.5 0.0014 19.0 0.2 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OWF42056.1 - 1e-17 64.2 2.7 2.1e-07 31.4 0.2 5.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF42056.1 - 7.4e-14 51.5 8.4 0.0057 17.1 0.4 6.4 6 0 0 6 6 6 4 Ankyrin repeat SOCS_box PF07525.16 OWF42056.1 - 1.5e-07 31.6 4.6 1.5e-07 31.6 4.6 2.2 2 0 0 2 2 2 1 SOCS box Ank_5 PF13857.6 OWF42056.1 - 3.6e-07 30.3 6.6 0.0069 16.7 1.9 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Hemocyanin_N PF03722.14 OWF42056.1 - 0.016 15.7 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain TUDOR PF00567.24 OWF42057.1 - 9.2e-118 387.3 13.1 1e-26 93.4 0.3 6.4 5 1 0 5 5 5 5 Tudor domain zf-B_box PF00643.24 OWF42057.1 - 2e-11 43.9 36.2 2.7e-10 40.2 3.3 4.3 3 1 0 3 3 3 2 B-box zinc finger Agenet PF05641.12 OWF42057.1 - 1.9e-08 34.6 10.8 0.11 13.0 0.3 5.5 6 0 0 6 6 6 3 Agenet domain zf-RING_UBOX PF13445.6 OWF42057.1 - 1.6e-07 31.3 4.9 1.6e-07 31.3 4.9 3.1 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF42057.1 - 8e-06 25.9 0.9 8e-06 25.9 0.9 4.1 4 0 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF42057.1 - 2.8e-05 23.9 3.0 2.8e-05 23.9 3.0 3.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF42057.1 - 0.00014 21.7 6.4 0.00014 21.7 6.4 3.2 2 0 0 2 2 2 1 zinc-RING finger domain DUF4537 PF15057.6 OWF42057.1 - 0.00033 20.7 4.5 0.35 10.9 0.1 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF4537) zf-C3HC4_2 PF13923.6 OWF42057.1 - 0.015 15.1 0.8 0.015 15.1 0.8 3.5 3 0 0 3 3 1 0 Zinc finger, C3HC4 type (RING finger) Tap-RNA_bind PF09162.10 OWF42057.1 - 0.026 14.4 0.1 16 5.4 0.0 3.6 2 0 0 2 2 2 0 Tap, RNA-binding DUF5082 PF16888.5 OWF42057.1 - 0.05 13.9 0.4 0.16 12.3 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SNase PF00565.17 OWF42057.1 - 0.06 13.8 0.0 1.3 9.6 0.0 2.9 2 0 0 2 2 2 0 Staphylococcal nuclease homologue Prok-RING_4 PF14447.6 OWF42057.1 - 5.5 6.9 25.5 0.026 14.4 0.9 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 rve PF00665.26 OWF42058.1 - 0.0047 17.1 0.0 12 6.2 0.0 4.6 1 1 0 1 1 1 1 Integrase core domain Baculo_LEF-10 PF07206.11 OWF42058.1 - 0.0067 16.6 58.7 1.8e+04 -43.9 58.7 8.9 1 1 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) Importin_rep_3 PF18806.1 OWF42058.1 - 0.86 9.7 22.2 64 3.7 0.5 6.4 1 1 10 11 11 11 0 Importin 13 repeat 7tm_1 PF00001.21 OWF42059.1 - 1.7e-26 93.1 9.7 2.3e-26 92.7 9.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ctr PF04145.15 OWF42059.1 - 0.028 15.0 2.8 0.029 15.0 1.0 2.1 2 1 0 2 2 2 0 Ctr copper transporter family DUF2721 PF11026.8 OWF42059.1 - 0.12 12.3 0.2 0.12 12.3 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) PulG PF11773.8 OWF42059.1 - 0.15 11.9 0.0 0.53 10.2 0.0 1.9 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Imm17 PF15562.6 OWF42059.1 - 0.45 10.4 3.8 3.3 7.6 1.3 3.4 2 1 1 3 3 3 0 Immunity protein 17 DUF2897 PF11446.8 OWF42059.1 - 5.2 7.0 4.9 1.6 8.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) S1FA PF04689.13 OWF42059.1 - 6.1 7.1 5.5 56 4.0 0.5 3.2 3 0 0 3 3 3 0 DNA binding protein S1FA zf-LITAF-like PF10601.9 OWF42059.1 - 6.5 7.1 8.8 2.9 8.2 0.0 3.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain 7tm_1 PF00001.21 OWF42060.1 - 4.3e-14 52.5 15.3 7.3e-14 51.7 15.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Xan_ur_permease PF00860.20 OWF42062.1 - 6.1e-78 262.2 27.1 9.9e-78 261.5 27.1 1.3 1 1 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 OWF42063.1 - 1.4e-79 267.6 27.1 2.6e-79 266.7 27.1 1.4 1 1 0 1 1 1 1 Permease family RCC1 PF00415.18 OWF42064.1 - 3e-51 171.8 14.8 2.6e-13 50.3 0.1 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF42064.1 - 2.1e-29 100.7 35.6 1.7e-08 34.0 0.1 8.3 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.20 OWF42064.1 - 7.6e-21 72.7 43.1 0.00054 19.7 0.6 8.9 8 0 0 8 8 8 7 MORN repeat VPS9 PF02204.18 OWF42064.1 - 5.5e-19 68.3 0.4 1.2e-18 67.2 0.4 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RhoGEF PF00621.20 OWF42064.1 - 0.0001 22.6 1.3 0.00018 21.8 0.2 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_13 PF16652.5 OWF42064.1 - 0.048 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 OWF42064.1 - 0.082 13.4 0.0 0.35 11.4 0.0 2.1 1 0 0 1 1 1 0 PH domain Ezh2_MCSS PF18600.1 OWF42064.1 - 0.084 12.5 1.3 0.97 9.1 0.2 2.6 2 0 0 2 2 2 0 MCSS domain TIR_2 PF13676.6 OWF42066.1 - 3.8e-20 72.7 0.0 1.3e-19 70.9 0.1 1.9 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 OWF42066.1 - 3.2e-09 36.8 0.6 1.5e-08 34.7 0.6 2.1 3 0 0 3 3 3 1 TIR domain TIR-like PF10137.9 OWF42066.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain TRADD_N PF09034.10 OWF42066.1 - 0.08 13.0 0.7 2 8.5 0.1 2.7 3 0 0 3 3 3 0 TRADD, N-terminal domain DUF4481 PF14800.6 OWF42066.1 - 0.94 8.9 6.3 0.62 9.5 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4481) DNA_primase_S PF01896.19 OWF42067.1 - 2e-59 200.6 1.1 3.1e-59 200.0 1.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit Plasmodium_HRP PF05403.11 OWF42068.1 - 0.071 12.9 0.0 3.2 7.5 0.0 2.3 1 1 2 3 3 3 0 Plasmodium histidine-rich protein (HRPII/III) zf-RING_6 PF14835.6 OWF42068.1 - 0.13 12.1 6.8 1.6 8.7 0.3 3.9 2 1 1 4 4 4 0 zf-RING of BARD1-type protein Rbsn PF11464.8 OWF42068.1 - 0.23 11.2 0.6 22 4.9 0.0 3.9 5 0 0 5 5 5 0 Rabenosyn Rab binding domain ABC_cobalt PF09819.9 OWF42070.1 - 0.082 13.0 2.8 1 9.5 2.7 2.5 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component POTRA_2 PF08479.11 OWF42072.1 - 0.27 11.1 4.7 1.4 8.8 0.3 3.3 2 2 2 4 4 4 0 POTRA domain, ShlB-type Plasmod_dom_1 PF09715.10 OWF42072.1 - 0.31 11.1 3.1 5.9 7.0 0.1 3.5 3 1 1 4 4 4 0 Plasmodium protein of unknown function (Plasmod_dom_1) DNA_mis_repair PF01119.19 OWF42072.1 - 0.33 10.6 1.0 19 4.9 0.1 2.6 1 1 1 2 2 2 0 DNA mismatch repair protein, C-terminal domain DUF4573 PF15140.6 OWF42073.1 - 0.063 13.1 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) C1q PF00386.21 OWF42074.1 - 3.2e-57 192.2 14.3 2.4e-23 82.7 1.7 3.5 3 0 0 3 3 3 3 C1q domain HEAT PF02985.22 OWF42074.1 - 3e-15 55.0 3.5 0.00094 19.2 0.1 7.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 OWF42074.1 - 2e-14 53.7 0.4 1.4e-09 38.2 0.1 6.1 5 1 1 6 6 6 2 HEAT-like repeat IBN_N PF03810.19 OWF42074.1 - 1.1e-09 38.0 2.9 2.3e-09 37.0 0.7 2.8 2 1 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 OWF42074.1 - 1.2e-07 31.9 4.8 0.00017 21.7 0.0 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OWF42074.1 - 2.2e-06 27.5 0.9 0.12 12.4 0.3 3.6 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF42074.1 - 2.8e-06 27.6 1.1 0.001 19.4 0.0 4.5 4 2 1 5 5 5 2 HEAT repeats CLASP_N PF12348.8 OWF42074.1 - 0.00024 20.7 2.7 0.57 9.7 0.0 4.2 3 1 1 4 4 4 2 CLASP N terminal BclA_C PF18573.1 OWF42074.1 - 0.086 12.7 8.0 7.4 6.5 0.5 3.7 3 1 0 3 3 3 0 BclA C-terminal domain 7tm_2 PF00002.24 OWF42076.1 - 8.6e-49 166.0 11.0 1.6e-48 165.2 11.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF42076.1 - 3.2e-11 43.4 5.0 6.7e-11 42.3 5.0 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF4079 PF13301.6 OWF42076.1 - 0.047 13.8 1.5 0.088 13.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Fibrinogen_C PF00147.18 OWF42077.1 - 4.1e-70 236.0 11.0 5.1e-70 235.7 11.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF42077.1 - 4.1e-05 23.5 0.1 0.00012 22.0 0.1 1.8 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 OWF42077.1 - 0.035 14.0 0.7 0.083 12.8 0.7 1.7 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 OWF42077.1 - 0.044 13.9 0.4 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 PAN-like domain RIIa PF02197.17 OWF42078.1 - 1.9e-05 24.2 0.0 5.2e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 OWF42078.1 - 0.00019 21.1 0.0 0.00069 19.3 0.0 2.0 2 0 0 2 2 2 1 Dpy-30 motif DUF5586 PF17824.1 OWF42078.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) DUF2501 PF10696.9 OWF42078.1 - 0.017 15.4 0.4 0.055 13.8 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) Radial_spoke PF04712.12 OWF42078.1 - 0.2 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CBM_14 PF01607.24 OWF42079.1 - 1.5e-09 37.9 15.7 4.2e-06 26.8 1.3 3.6 3 1 0 3 3 3 3 Chitin binding Peritrophin-A domain VWA PF00092.28 OWF42080.1 - 1.2e-130 432.6 13.5 5.4e-38 131.0 0.1 4.1 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_2 PF13519.6 OWF42080.1 - 4.5e-48 162.3 3.7 5.5e-12 46.3 0.0 4.8 5 0 0 5 5 5 4 von Willebrand factor type A domain VWA_3 PF13768.6 OWF42080.1 - 1.7e-18 67.0 1.9 8.9e-06 25.7 0.0 4.9 4 2 0 4 4 4 4 von Willebrand factor type A domain Copine PF07002.16 OWF42080.1 - 1.2e-10 41.3 0.7 0.003 17.0 0.1 3.4 3 0 0 3 3 3 3 Copine vWA-TerF-like PF10138.9 OWF42080.1 - 3.2e-09 37.2 1.8 0.1 12.7 0.0 4.3 4 0 0 4 4 4 3 vWA found in TerF C terminus NACHT PF05729.12 OWF42080.1 - 0.01 15.8 0.1 18 5.2 0.0 3.9 4 0 0 4 4 4 0 NACHT domain PGM_PMM_I PF02878.16 OWF42080.1 - 0.025 14.3 0.5 7.7 6.2 0.1 2.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OWF42080.1 - 0.038 14.2 0.2 46 4.2 0.0 4.3 5 0 0 5 5 5 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Integrin_beta PF00362.18 OWF42080.1 - 0.056 13.1 0.1 6.6 6.3 0.0 3.2 4 0 0 4 4 4 0 Integrin beta chain VWA domain TmoB PF06234.12 OWF42080.1 - 0.13 12.4 0.1 8.9 6.5 0.0 3.1 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) NAD_binding_2 PF03446.15 OWF42080.1 - 0.21 11.7 3.0 1e+02 3.0 0.1 4.1 4 0 0 4 4 4 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3439 PF11921.8 OWF42080.1 - 9.5 6.2 30.8 7 6.6 5.9 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) RRM_3 PF08777.11 OWF42081.1 - 3e-24 85.0 1.2 3e-24 85.0 1.2 2.8 3 0 0 3 3 3 1 RNA binding motif La PF05383.17 OWF42081.1 - 5.8e-23 80.7 0.1 1.8e-22 79.1 0.1 1.9 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OWF42081.1 - 1.7e-10 40.6 0.8 2.2e-06 27.4 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OWF42081.1 - 0.0014 18.6 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NCBP3 PF10309.9 OWF42081.1 - 0.033 14.0 0.2 0.75 9.7 0.0 2.6 2 1 0 2 2 2 0 Nuclear cap-binding protein subunit 3 Pal1 PF08316.11 OWF42081.1 - 1.3 9.7 4.6 0.81 10.4 0.2 2.4 2 0 0 2 2 2 0 Pal1 cell morphology protein Band_7 PF01145.25 OWF42082.1 - 2.5e-25 89.5 1.7 3.2e-25 89.1 1.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Sod_Fe_C PF02777.18 OWF42083.1 - 3.1e-35 120.4 0.6 9e-35 118.9 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OWF42083.1 - 4.6e-23 81.5 0.2 1.1e-22 80.3 0.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CSRNP_N PF16019.5 OWF42084.1 - 5.6e-93 310.9 10.3 1.4e-92 309.6 10.3 1.7 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus RNA_pol_3_Rpc31 PF11705.8 OWF42084.1 - 0.0085 16.4 5.1 0.025 14.8 5.1 1.8 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 YebO PF13974.6 OWF42084.1 - 0.0089 16.1 0.3 0.03 14.4 0.3 1.9 1 0 0 1 1 1 1 YebO-like protein DNA_pol_phi PF04931.13 OWF42084.1 - 0.81 7.7 6.2 1.4 6.9 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 OWF42084.1 - 1.4 8.9 7.5 0.16 12.0 2.5 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Spc7 PF08317.11 OWF42085.1 - 0.00055 18.9 17.0 0.00055 18.9 17.0 6.7 6 2 1 7 7 7 1 Spc7 kinetochore protein DUF503 PF04456.12 OWF42085.1 - 8.7 6.3 10.7 1.1 9.2 4.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF503) LETM1 PF07766.13 OWF42086.1 - 3.4e-35 121.7 0.4 4.6e-35 121.3 0.4 1.2 1 0 0 1 1 1 1 LETM1-like protein Neur_chan_LBD PF02931.23 OWF42087.1 - 6.9e-35 120.4 0.0 1.2e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF42087.1 - 8.4e-12 45.7 16.7 5.8e-11 42.9 11.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF1772 PF08592.11 OWF42087.1 - 0.046 14.0 0.7 0.12 12.7 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF5634_N PF18672.1 OWF42087.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5634) Proton_antipo_C PF01010.19 OWF42087.1 - 0.4 10.3 5.2 1.5 8.4 0.6 2.3 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Pox_RNA_Pol_22 PF05273.13 OWF42088.1 - 1.6e-05 24.7 8.6 0.43 10.3 0.4 5.1 1 1 4 5 5 5 4 Poxvirus RNA polymerase 22 kDa subunit 4HPAD_g_N PF18671.1 OWF42088.1 - 2.6e-05 23.8 0.6 41 4.0 0.0 6.9 8 0 0 8 8 8 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal DUF4122 PF13498.6 OWF42088.1 - 9.3e-05 22.2 0.2 2.9 7.6 0.0 3.4 1 1 2 3 3 3 3 Domain of unknown function (DUF4122) LPD28 PF18843.1 OWF42088.1 - 0.00018 21.1 2.7 1.3 8.7 0.1 3.9 1 1 2 4 4 4 3 Large polyvalent protein associated domain 28 MBF2 PF15868.5 OWF42088.1 - 0.0017 18.8 0.6 1.7 9.3 0.0 2.7 1 1 2 3 3 3 2 Transcription activator MBF2 DUF1942 PF09167.11 OWF42088.1 - 0.0078 16.2 8.3 7.2 6.6 0.2 3.8 1 1 2 4 4 4 3 Domain of unknown function (DUF1942) 2-Hacid_dh_C PF02826.19 OWF42089.1 - 1.3e-53 181.0 0.0 2e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF42089.1 - 9.4e-32 109.5 0.0 1.1e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 OWF42089.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 OWF42089.1 - 0.046 13.1 0.8 0.31 10.4 0.2 2.3 2 1 1 3 3 3 0 ThiF family NAD_binding_2 PF03446.15 OWF42089.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Innexin PF00876.18 OWF42090.1 - 1.1e-116 390.0 15.0 1.2e-116 389.8 15.0 1.0 1 0 0 1 1 1 1 Innexin SH2 PF00017.24 OWF42090.1 - 0.016 15.3 0.0 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 SH2 domain Innexin PF00876.18 OWF42091.1 - 1.9e-117 392.5 20.3 2.1e-117 392.3 20.3 1.0 1 0 0 1 1 1 1 Innexin HepII_C PF18675.1 OWF42091.1 - 0.19 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Heparinase II C-terminal domain Dynein_light PF01221.18 OWF42091.1 - 0.21 11.9 3.8 0.28 11.6 0.1 2.7 3 0 0 3 3 3 0 Dynein light chain type 1 Nairovirus_M PF07948.11 OWF42091.1 - 0.63 8.2 3.3 0.49 8.5 1.9 1.4 2 0 0 2 2 2 0 Nairovirus M polyprotein-like SieB PF14163.6 OWF42091.1 - 1.3 8.5 6.9 9.3 5.7 4.4 2.6 1 1 0 2 2 2 0 Super-infection exclusion protein B Innexin PF00876.18 OWF42092.1 - 2.1e-111 372.7 19.5 2.4e-111 372.5 19.5 1.0 1 0 0 1 1 1 1 Innexin Gemini_AL1 PF00799.20 OWF42092.1 - 0.065 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Innexin PF00876.18 OWF42093.1 - 4.2e-119 397.9 17.5 4.9e-119 397.7 17.5 1.0 1 0 0 1 1 1 1 Innexin FMO-like PF00743.19 OWF42094.1 - 1.6e-77 261.1 0.0 7.6e-55 186.3 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF42094.1 - 3e-14 53.0 0.5 4.7e-09 35.9 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF42094.1 - 3.8e-14 52.6 0.0 3.2e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF42094.1 - 2.1e-08 33.7 0.1 8.9e-05 21.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OWF42094.1 - 4.6e-07 29.9 0.0 8.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF42094.1 - 2.1e-05 24.7 0.0 6.4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF42094.1 - 6.7e-05 22.6 0.3 0.0067 16.1 0.1 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OWF42094.1 - 0.0002 21.9 0.1 0.016 15.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 7tm_1 PF00001.21 OWF42095.1 - 3.9e-24 85.4 5.7 5.4e-24 84.9 5.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Fibrinogen_C PF00147.18 OWF42097.1 - 4e-61 206.6 12.7 4.5e-61 206.5 12.7 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain 7tm_1 PF00001.21 OWF42098.1 - 1.1e-17 64.3 15.6 1.4e-17 63.9 15.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF42098.1 - 2.3e-09 37.3 18.7 5.1e-09 36.2 18.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Fibrinogen_C PF00147.18 OWF42099.1 - 7.8e-58 195.9 8.4 9.2e-58 195.6 8.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SopD PF11047.8 OWF42099.1 - 0.0087 15.3 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Salmonella outer protein D CDO_I PF05995.12 OWF42099.1 - 0.067 12.5 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Cysteine dioxygenase type I Reprolysin_5 PF13688.6 OWF42100.1 - 5.5e-16 59.3 3.6 1.7e-15 57.7 3.6 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 ADAM_CR_2 PF17771.1 OWF42100.1 - 6.6e-14 52.2 10.3 6.6e-14 52.2 10.3 3.4 2 1 1 3 3 3 1 ADAM cysteine-rich domain Reprolysin PF01421.19 OWF42100.1 - 1.1e-13 51.5 1.4 1.1e-12 48.2 1.4 2.3 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 OWF42100.1 - 3.8e-10 40.4 0.8 1.3e-09 38.6 0.8 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF42100.1 - 3.5e-05 23.5 4.3 3.5e-05 23.5 4.3 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF42100.1 - 0.00015 21.7 5.2 0.00018 21.4 3.8 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like LYRIC PF15686.5 OWF42100.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Mlh1_C PF16413.5 OWF42101.1 - 2.4e-93 312.4 0.4 6.8e-93 310.9 0.4 1.7 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OWF42101.1 - 7e-33 112.8 3.2 1.2e-32 112.0 0.8 2.5 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain 7tm_1 PF00001.21 OWF42102.1 - 2e-23 83.1 22.6 3.3e-23 82.4 22.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF42102.1 - 0.067 12.8 33.9 0.031 13.9 21.6 2.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Y_phosphatase PF00102.27 OWF42103.1 - 5.2e-109 363.3 5.2 4.8e-72 242.3 0.3 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 OWF42103.1 - 1.2e-06 28.6 0.7 2.5e-06 27.6 0.7 1.5 1 0 0 1 1 1 1 F5/8 type C domain DSPc PF00782.20 OWF42103.1 - 3.3e-06 27.0 0.2 0.0053 16.6 0.0 2.8 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF42103.1 - 0.00049 20.2 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF42103.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family SKG6 PF08693.10 OWF42103.1 - 0.037 13.5 0.3 0.086 12.3 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OWF42103.1 - 0.039 14.8 0.0 0.14 13.0 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 OWF42103.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RWD PF05773.22 OWF42104.1 - 2.3e-16 60.1 0.2 3.9e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 OWF42104.1 - 3.8e-06 27.1 0.4 0.061 13.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1115) YTH PF04146.15 OWF42105.1 - 6.6e-41 140.0 0.2 6.6e-41 140.0 0.2 3.9 2 2 0 2 2 2 1 YT521-B-like domain Y_phosphatase PF00102.27 OWF42106.1 - 4.5e-108 360.3 1.7 1.4e-71 240.8 0.2 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 OWF42106.1 - 1.1e-08 35.2 1.0 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain Y_phosphatase3 PF13350.6 OWF42106.1 - 9.4e-05 22.5 0.1 0.018 15.0 0.1 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 OWF42106.1 - 0.00011 22.1 0.1 0.0064 16.3 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF42106.1 - 0.0028 17.8 0.1 0.011 15.9 0.1 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate SKG6 PF08693.10 OWF42106.1 - 0.0058 16.0 1.2 0.011 15.1 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DEFB136 PF17333.2 OWF42106.1 - 4.3 7.4 98.2 1 9.3 0.4 13.3 11 1 1 12 12 12 0 Beta defensin 136 KRTAP PF11759.8 OWF42107.1 - 0.89 10.1 80.4 1.8e+04 -44.7 80.4 6.4 1 1 0 1 1 1 0 Keratin-associated matrix Guanylate_cyc PF00211.20 OWF42108.1 - 9.9e-65 217.6 0.1 1.8e-64 216.7 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF42108.1 - 1.9e-36 125.7 0.0 3.4e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF42108.1 - 2.2e-26 92.8 0.0 4.2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF42108.1 - 1e-05 25.1 2.1 1.5e-05 24.5 2.1 1.2 1 0 0 1 1 1 1 Heme NO binding associated YabA PF06156.13 OWF42109.1 - 0.4 11.3 10.1 0.48 11.1 1.0 3.2 1 1 2 3 3 3 0 Initiation control protein YabA GIT_CC PF16559.5 OWF42109.1 - 1.5 8.7 5.6 3.4 7.6 0.1 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 OWF42109.1 - 3.1 7.8 13.8 0.12 12.4 5.4 2.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ras PF00071.22 OWF42110.1 - 5.2e-63 211.5 1.6 6.4e-63 211.2 1.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF42110.1 - 3.2e-33 114.5 1.5 3.6e-33 114.3 0.7 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF42110.1 - 2e-14 53.4 0.3 2.6e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF42110.1 - 5e-05 22.8 0.2 0.00026 20.5 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF42110.1 - 0.00035 20.6 0.1 0.00098 19.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF42110.1 - 0.00049 19.5 0.2 0.00068 19.1 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OWF42110.1 - 0.00053 19.9 0.1 0.098 12.6 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OWF42110.1 - 0.00055 19.5 0.1 0.0017 17.9 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OWF42110.1 - 0.0035 16.5 1.2 4.7 6.3 0.0 3.0 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 OWF42110.1 - 0.0065 16.0 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B Mit_proteolip PF08039.11 OWF42111.1 - 0.042 14.3 0.1 0.15 12.5 0.1 2.0 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF4381 PF14316.6 OWF42111.1 - 0.75 10.0 13.4 0.37 11.0 1.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) HEAT_EZ PF13513.6 OWF42112.1 - 2.3e-33 114.2 0.7 1.1e-12 48.2 0.0 10.7 9 2 3 12 12 12 4 HEAT-like repeat HEAT PF02985.22 OWF42112.1 - 8.2e-28 94.1 1.6 0.076 13.3 0.0 10.9 10 0 0 10 10 10 7 HEAT repeat IBN_N PF03810.19 OWF42112.1 - 3.3e-17 62.1 0.0 1.1e-16 60.5 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 OWF42112.1 - 7.4e-16 58.3 0.0 0.00027 21.3 0.0 6.6 5 2 1 6 6 6 3 HEAT repeats Arm PF00514.23 OWF42112.1 - 4.7e-14 51.8 0.5 0.56 10.3 0.0 8.4 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 OWF42112.1 - 3.5e-12 46.7 0.1 0.028 14.4 0.7 4.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OWF42112.1 - 4.8e-11 43.1 0.3 0.0023 18.5 1.0 5.5 3 2 3 6 6 6 5 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OWF42112.1 - 4.4e-07 28.8 2.9 0.059 11.9 0.1 4.2 2 2 1 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.8 OWF42112.1 - 2.8e-05 23.4 1.0 1 8.4 0.0 5.5 4 2 0 5 5 5 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 OWF42112.1 - 0.0015 18.2 0.5 0.059 12.9 0.0 3.6 3 2 0 4 4 4 1 CLASP N terminal UNC45-central PF11701.8 OWF42112.1 - 0.0028 17.6 1.9 0.11 12.5 0.2 3.7 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 OWF42112.1 - 0.0037 17.4 0.1 0.36 11.0 0.0 4.0 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 OWF42112.1 - 0.015 14.4 0.1 0.084 12.0 0.0 2.2 2 0 0 2 2 2 0 Dopey, N-terminal CRM1_C PF08767.11 OWF42112.1 - 0.017 14.3 0.1 5 6.2 0.0 2.6 2 0 0 2 2 2 0 CRM1 C terminal Patched PF02460.18 OWF42113.1 - 6.6e-100 335.4 14.0 8.6e-100 335.0 14.0 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF42113.1 - 1.2e-38 132.4 1.3 1.2e-38 132.4 1.3 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OWF42113.1 - 0.00053 17.8 6.3 0.00053 17.8 6.3 1.7 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family SafA PF17073.5 OWF42113.1 - 0.0075 16.2 1.2 0.0075 16.2 1.2 2.2 2 0 0 2 2 2 1 Two-component-system connector protein IL17 PF06083.11 OWF42114.1 - 7.6e-16 58.4 9.3 1.3e-15 57.7 8.5 1.8 2 0 0 2 2 2 1 Interleukin-17 PSRT PF07636.11 OWF42114.1 - 0.044 13.5 2.4 2.7 7.8 0.3 3.0 2 0 0 2 2 2 0 PSRT DUF4215 PF13948.6 OWF42114.1 - 0.63 10.5 6.8 1.5 9.3 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) IL17 PF06083.11 OWF42115.1 - 3.6e-17 62.6 6.2 8.2e-17 61.5 6.2 1.6 1 0 0 1 1 1 1 Interleukin-17 SAM_2 PF07647.17 OWF42117.1 - 1.7e-09 37.6 0.2 3.4e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF42117.1 - 1.8e-08 34.7 0.2 3.1e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF42117.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF1474 PF07342.11 OWF42117.1 - 0.023 15.2 5.9 8.3 7.0 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1474) DNA_pol_A_exoN PF18305.1 OWF42117.1 - 0.25 11.7 2.2 9.6 6.6 0.2 2.7 1 1 1 2 2 2 0 3' to 5' exonuclease C-terminal domain FSA_C PF10479.9 OWF42117.1 - 0.32 9.1 17.0 0.41 8.7 17.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CAC1F_C PF16885.5 OWF42117.1 - 0.46 10.1 8.8 0.61 9.7 8.8 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF4712 PF15830.5 OWF42117.1 - 0.53 9.9 8.5 0.73 9.5 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) ATG16 PF08614.11 OWF42117.1 - 2.5 8.3 9.1 4.8 7.3 9.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GREB1 PF15782.5 OWF42117.1 - 6.2 3.8 13.5 7.3 3.6 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Methyltransf_15 PF09445.10 OWF42118.1 - 2.1e-42 144.5 0.0 4.3e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OWF42118.1 - 3.4e-07 30.2 0.0 7.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 OWF42118.1 - 9.5e-07 28.7 0.1 2.3e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OWF42118.1 - 1.1e-06 28.5 0.0 7.8e-06 25.7 0.0 2.4 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 OWF42118.1 - 1.2e-06 29.1 0.2 4.5e-06 27.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF42118.1 - 2.5e-05 24.0 0.0 6.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 OWF42118.1 - 0.00057 19.5 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OWF42118.1 - 0.002 18.8 0.6 0.0061 17.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OWF42118.1 - 0.0028 17.6 0.0 0.0077 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OWF42118.1 - 0.0035 16.8 0.0 0.0035 16.8 0.0 2.9 4 0 0 4 4 4 1 Ribosomal protein L11 methyltransferase (PrmA) DUF840 PF05801.11 OWF42118.1 - 0.32 11.1 2.4 0.87 9.7 1.5 2.2 1 1 1 2 2 2 0 Lagovirus protein of unknown function (DUF840) SNRNP27 PF08648.12 OWF42118.1 - 0.66 10.1 4.1 4.4 7.5 4.1 2.5 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins 2OG-FeII_Oxy_2 PF13532.6 OWF42119.1 - 1.5e-09 38.3 0.2 1.7e-08 34.9 0.2 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 OWF42120.1 - 1.5e-20 73.2 5.6 0.0071 17.2 0.1 9.4 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF42120.1 - 7.8e-05 22.9 0.1 1.5 9.2 0.1 5.5 5 3 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 OWF42120.1 - 0.00025 21.4 44.9 0.001 19.4 25.7 4.8 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) ADIP PF11559.8 OWF42120.1 - 0.011 15.9 11.8 0.011 15.9 11.8 5.9 2 2 4 6 6 6 0 Afadin- and alpha -actinin-Binding Spc110_C PF18520.1 OWF42121.1 - 4.2e-07 29.4 0.4 36 4.1 0.0 7.7 8 0 0 8 8 8 2 Spindle pole body component 110 C-terminal domain zf-CHY PF05495.12 OWF42121.1 - 0.0018 18.7 15.8 0.46 11.0 0.2 6.9 3 2 4 7 7 7 2 CHY zinc finger Homeobox_KN PF05920.11 OWF42122.1 - 1.3e-16 60.2 0.2 1.3e-16 60.2 0.2 2.1 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 OWF42122.1 - 7e-07 29.0 1.3 9.4e-07 28.6 0.3 1.8 2 0 0 2 2 2 1 Homeodomain HEXIM PF15313.6 OWF42122.1 - 3.3 7.9 7.9 0.53 10.5 3.6 1.9 2 1 1 3 3 3 0 Hexamethylene bis-acetamide-inducible protein Phosphodiest PF01663.22 OWF42123.1 - 1.1e-15 58.1 0.9 1.5e-09 37.9 0.2 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF42123.1 - 6.4e-08 32.3 0.1 2.5e-06 27.1 0.1 2.2 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 OWF42123.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Protoglobin PF11563.8 OWF42123.1 - 0.12 12.2 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Protoglobin ArsA_ATPase PF02374.15 OWF42124.1 - 3.1e-116 387.8 0.3 3.6e-116 387.6 0.3 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OWF42124.1 - 2.4e-10 40.6 0.0 6.6e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 OWF42124.1 - 3.7e-10 39.9 0.0 5.8e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 OWF42124.1 - 2.8e-06 27.0 0.0 1.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 OWF42124.1 - 6.2e-05 22.6 0.0 9.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 OWF42124.1 - 0.00014 21.4 0.2 0.00065 19.2 0.0 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 OWF42124.1 - 0.0053 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Elf1 PF05129.13 OWF42124.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AAA_25 PF13481.6 OWF42124.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OWF42124.1 - 0.054 12.8 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 OWF42124.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 OWF42124.1 - 0.17 12.4 0.0 0.27 11.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Steroid_dh PF02544.16 OWF42125.1 - 8.6e-30 103.7 3.3 8.6e-30 103.7 3.3 2.6 3 0 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase ELO PF01151.18 OWF42126.1 - 2.1e-65 220.7 23.5 2.7e-65 220.4 23.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3600 PF12207.8 OWF42126.1 - 0.017 15.0 1.7 0.027 14.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) LETM1 PF07766.13 OWF42126.1 - 0.019 14.3 1.6 0.028 13.8 1.6 1.2 1 0 0 1 1 1 0 LETM1-like protein Amidase_6 PF12671.7 OWF42126.1 - 0.83 9.7 8.7 2.3 8.3 4.4 2.3 1 1 1 2 2 2 0 Putative amidase domain Zip PF02535.22 OWF42126.1 - 1.7 7.8 5.2 3.3 6.8 5.2 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter zf-C2H2_4 PF13894.6 OWF42127.1 - 3.6e-21 74.0 48.3 0.0049 17.6 0.4 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF42127.1 - 6.2e-20 70.5 54.2 4.3e-05 23.7 4.9 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF42127.1 - 6e-11 42.3 49.7 0.00068 20.0 1.1 8.3 8 1 0 8 8 8 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF42127.1 - 4.9e-07 29.9 43.9 0.0019 18.5 0.4 7.2 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 OWF42127.1 - 0.0093 15.5 32.6 0.35 10.5 0.1 6.8 7 0 0 7 7 7 3 Ubiquitin-Binding Zinc Finger zf_Hakai PF18408.1 OWF42127.1 - 0.03 14.0 0.9 0.03 14.0 0.9 2.7 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 OWF42127.1 - 0.03 14.3 3.2 0.03 14.3 3.2 7.3 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OWF42127.1 - 0.044 13.7 24.0 4.7 7.2 0.3 6.4 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 OWF42127.1 - 0.069 13.9 30.4 0.18 12.5 3.4 3.9 2 2 0 3 3 3 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 OWF42127.1 - 0.096 12.8 35.5 0.2 11.8 5.1 6.1 3 2 2 5 5 5 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 OWF42127.1 - 0.21 11.9 22.4 3.7 7.9 9.2 3.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon TF_Zn_Ribbon PF08271.12 OWF42127.1 - 0.41 10.2 0.0 0.41 10.2 0.0 4.6 6 2 0 6 6 6 0 TFIIB zinc-binding XPA_N PF01286.18 OWF42127.1 - 0.75 9.9 28.1 1.9 8.6 0.4 6.4 6 0 0 6 6 6 0 XPA protein N-terminal zf-HYPF PF07503.12 OWF42127.1 - 0.82 9.5 0.1 0.82 9.5 0.1 4.5 6 0 0 6 6 6 0 HypF finger C1_4 PF07975.12 OWF42127.1 - 1 9.6 29.5 0.99 9.7 3.5 4.9 1 1 4 5 5 5 0 TFIIH C1-like domain BolA PF01722.18 OWF42127.1 - 1.9 8.8 5.4 5.4 7.4 0.1 3.1 2 1 2 4 4 4 0 BolA-like protein zf-met PF12874.7 OWF42127.1 - 2 8.9 0.0 2 8.9 0.0 6.3 7 0 0 7 7 6 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OWF42128.1 - 1.1e-21 75.6 48.2 0.0039 17.9 3.2 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF42128.1 - 2.9e-20 71.5 53.9 2.9e-05 24.3 4.9 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF42128.1 - 2.3e-11 43.6 50.0 0.00045 20.5 1.1 8.2 8 1 0 8 8 8 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF42128.1 - 1.2e-07 31.8 44.5 0.0013 19.0 0.4 7.2 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 OWF42128.1 - 0.00038 20.0 30.1 0.44 10.2 0.1 6.7 7 0 0 7 7 7 3 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OWF42128.1 - 0.0035 17.4 32.9 0.062 13.4 0.4 5.9 5 2 1 6 6 6 2 Zinc ribbon domain zf-C2H2_6 PF13912.6 OWF42128.1 - 0.0085 16.1 42.4 0.021 14.8 3.2 7.3 7 0 0 7 7 7 2 C2H2-type zinc finger zf_Hakai PF18408.1 OWF42128.1 - 0.018 14.8 0.7 0.018 14.8 0.7 3.1 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zinc_ribbon_15 PF17032.5 OWF42128.1 - 0.039 14.7 31.5 0.12 13.2 3.3 3.8 1 1 2 4 4 4 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 OWF42128.1 - 0.041 13.8 6.7 0.041 13.8 6.7 4.5 2 2 2 4 4 3 0 SprT-like zinc ribbon domain Phage_int_SAM_2 PF12834.7 OWF42128.1 - 0.1 13.3 1.6 10 6.9 0.1 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal zf-C2H2_8 PF15909.5 OWF42128.1 - 0.14 12.5 25.2 2.9 8.3 5.6 3.6 1 1 3 4 4 4 0 C2H2-type zinc ribbon BolA PF01722.18 OWF42128.1 - 0.38 11.0 4.8 3.6 7.9 0.0 3.2 2 1 2 4 4 4 0 BolA-like protein XPA_N PF01286.18 OWF42128.1 - 0.53 10.4 30.7 1.7 8.8 0.8 6.5 7 1 0 7 7 6 0 XPA protein N-terminal zf-HYPF PF07503.12 OWF42128.1 - 0.65 9.8 0.1 0.65 9.8 0.1 4.8 6 0 0 6 6 6 0 HypF finger zf-C2HC_2 PF13913.6 OWF42128.1 - 0.97 9.4 31.0 3.2 7.8 0.3 6.6 7 0 0 7 7 6 0 zinc-finger of a C2HC-type zf-met PF12874.7 OWF42128.1 - 1.4 9.4 0.0 1.4 9.4 0.0 6.4 7 0 0 7 7 6 0 Zinc-finger of C2H2 type C1_4 PF07975.12 OWF42128.1 - 3 8.1 33.6 0.73 10.1 3.7 4.9 1 1 5 6 6 6 0 TFIIH C1-like domain DUF3268 PF11672.8 OWF42128.1 - 7 7.0 18.0 2 8.7 2.9 3.4 2 1 1 3 3 3 0 zinc-finger-containing domain ELO PF01151.18 OWF42129.1 - 6.5e-65 219.1 24.7 8.7e-65 218.7 24.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3146 PF11344.8 OWF42131.1 - 9.2e-05 22.0 0.1 19 5.0 0.0 5.4 2 2 3 6 6 6 1 Protein of unknown function (DUF3146) TMEM191C PF15194.6 OWF42131.1 - 0.01 16.0 0.2 4.4 7.5 0.0 2.8 2 2 0 2 2 2 0 TMEM191C family Cytokin_check_N PF10407.9 OWF42132.1 - 0.0013 18.7 6.8 0.009 15.9 1.4 3.0 2 1 1 3 3 3 1 Cdc14 phosphatase binding protein N-terminus Helo_like_N PF17111.5 OWF42132.1 - 0.0093 15.4 0.4 0.014 14.8 0.2 1.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF2185 PF09951.9 OWF42132.1 - 0.037 13.8 0.6 8.4 6.3 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2185) DUF4024 PF13216.6 OWF42132.1 - 0.3 11.1 8.6 5.7 7.0 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4024) Desmo_N PF06771.11 OWF42132.1 - 2 8.8 13.0 8.5 6.8 2.0 3.4 1 1 2 3 3 3 0 Viral Desmoplakin N-terminus Desmo_N PF06771.11 OWF42133.1 - 0.0004 20.7 19.9 1.8 8.9 2.8 4.4 1 1 3 4 4 4 4 Viral Desmoplakin N-terminus Vps51 PF08700.11 OWF42133.1 - 0.028 14.5 23.7 3.9 7.6 2.5 4.4 1 1 4 5 5 5 0 Vps51/Vps67 Ubiquitin_3 PF14836.6 OWF42133.1 - 0.063 13.3 10.0 11 6.1 1.4 3.5 1 1 1 2 2 2 0 Ubiquitin-like domain PIN_6 PF17146.4 OWF42133.1 - 0.077 13.5 6.3 0.65 10.5 5.6 2.2 1 1 1 2 2 2 0 PIN domain of ribonuclease CAMP_factor PF07373.11 OWF42133.1 - 0.1 12.2 5.5 0.23 11.0 5.1 1.6 1 1 0 1 1 1 0 CAMP factor (Cfa) DASH_Dad4 PF08650.10 OWF42133.1 - 0.39 10.7 7.2 19 5.3 0.5 3.0 1 1 2 3 3 3 0 DASH complex subunit Dad4 DUF5405 PF17399.2 OWF42133.1 - 0.43 10.9 14.2 34 4.8 7.3 3.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5405) Snf7 PF03357.21 OWF42133.1 - 0.66 9.5 10.0 5.5 6.5 10.0 2.0 1 1 0 1 1 1 0 Snf7 Allexi_40kDa PF05549.11 OWF42133.1 - 1.8 8.0 8.4 2.3 7.6 8.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein TBK1_CCD1 PF18394.1 OWF42133.1 - 2 7.9 22.0 4.5e+03 -3.1 22.0 2.9 1 1 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 7tm_1 PF00001.21 OWF42134.1 - 8.4e-36 123.6 8.9 1e-35 123.4 8.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF42134.1 - 1.1e-12 48.1 9.6 1.7e-12 47.5 8.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF42134.1 - 1.2e-10 41.2 7.1 2.2e-10 40.4 7.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 OWF42134.1 - 0.00046 19.8 1.3 0.00046 19.8 1.3 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc zf-LITAF-like PF10601.9 OWF42134.1 - 6.6 7.1 7.9 2.8 8.3 0.2 3.5 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain CENP-F_leu_zip PF10473.9 OWF42135.1 - 0.0014 18.6 15.9 0.0019 18.2 0.9 3.2 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 OWF42135.1 - 0.008 16.2 1.8 1.3 9.0 0.5 3.4 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 OWF42135.1 - 0.0081 16.7 8.2 2.6 8.6 7.4 3.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SOGA PF11365.8 OWF42135.1 - 0.01 16.9 8.2 2 9.6 1.5 4.0 4 1 1 5 5 3 0 Protein SOGA DUF1664 PF07889.12 OWF42135.1 - 0.014 15.5 19.7 0.15 12.1 0.4 4.2 3 1 2 5 5 4 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 OWF42135.1 - 0.016 15.3 20.6 2.8 7.9 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) V-SNARE PF05008.15 OWF42135.1 - 0.017 15.5 0.5 0.017 15.5 0.5 3.2 5 1 0 5 5 2 0 Vesicle transport v-SNARE protein N-terminus DUF4618 PF15397.6 OWF42135.1 - 0.028 13.8 17.6 0.059 12.8 8.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TLE_N PF03920.15 OWF42135.1 - 0.046 13.8 1.4 0.11 12.6 0.2 2.1 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain HCMV_UL139 PF12507.8 OWF42135.1 - 0.073 13.4 2.1 12 6.3 0.1 2.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Atg14 PF10186.9 OWF42135.1 - 0.14 11.2 8.0 2.2 7.3 5.6 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 OWF42135.1 - 0.17 12.5 5.4 6.9 7.3 0.4 3.9 3 1 1 4 4 3 0 Bone marrow stromal antigen 2 APG6_N PF17675.1 OWF42135.1 - 0.21 12.1 8.0 23 5.5 8.0 2.8 1 1 0 1 1 1 0 Apg6 coiled-coil region THOC7 PF05615.13 OWF42135.1 - 0.3 11.4 9.0 1.3 9.4 2.6 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 DUF641 PF04859.12 OWF42135.1 - 0.32 11.3 8.8 8 6.8 0.4 3.3 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) WXG100 PF06013.12 OWF42135.1 - 0.46 10.8 6.5 18 5.7 0.1 4.3 3 2 1 4 4 4 0 Proteins of 100 residues with WXG Spc7 PF08317.11 OWF42135.1 - 0.47 9.3 11.9 2.5 6.9 0.9 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 OWF42135.1 - 0.49 10.7 19.5 0.28 11.4 13.1 3.2 2 1 1 3 3 3 0 Zinc finger-containing protein SlyX PF04102.12 OWF42135.1 - 0.86 10.3 12.6 0.24 12.0 1.4 4.4 3 2 0 3 3 3 0 SlyX Csm1_N PF18504.1 OWF42135.1 - 1.2 9.5 11.3 3 8.3 1.0 4.0 3 1 1 4 4 4 0 Csm1 N-terminal domain LPP PF04728.13 OWF42135.1 - 1.3 9.5 9.8 64 4.1 0.8 4.7 3 1 0 4 4 4 0 Lipoprotein leucine-zipper DUF1759 PF03564.15 OWF42135.1 - 1.4 8.9 5.0 1.8 8.5 0.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1759) Hrs_helical PF12210.8 OWF42135.1 - 1.8 9.2 13.9 0.94 10.1 3.1 3.3 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4201 PF13870.6 OWF42135.1 - 1.8 8.3 15.0 0.88 9.3 1.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) DUF3618 PF12277.8 OWF42135.1 - 2.1 8.6 4.9 3.9 7.8 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) Apolipoprotein PF01442.18 OWF42135.1 - 2.4 8.0 10.0 8.8 6.2 10.0 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prefoldin_2 PF01920.20 OWF42135.1 - 3.1 7.8 13.7 11 6.1 0.6 4.0 2 1 1 3 3 3 0 Prefoldin subunit Tup_N PF08581.10 OWF42135.1 - 4.2 7.8 13.1 5 7.5 0.5 3.5 3 1 0 3 3 2 0 Tup N-terminal CC2-LZ PF16516.5 OWF42135.1 - 4.3 7.8 15.5 8.6 6.8 6.3 3.9 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Gly-zipper_Omp PF13488.6 OWF42135.1 - 4.4 7.4 5.0 7 6.7 5.0 1.3 1 0 0 1 1 1 0 Glycine zipper DUF2730 PF10805.8 OWF42135.1 - 5.4 7.2 8.8 9.5 6.4 0.9 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) Prominin PF05478.11 OWF42135.1 - 6 4.7 9.0 19 3.1 2.6 2.1 1 1 1 2 2 2 0 Prominin DUF3450 PF11932.8 OWF42135.1 - 6.1 6.1 16.4 0.56 9.5 1.5 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 OWF42135.1 - 9.7 6.3 11.7 0.37 10.8 1.5 3.5 4 1 0 4 4 3 0 TATA element modulatory factor 1 DNA binding efThoc1 PF11957.8 OWF42136.1 - 1.2e-137 459.6 19.5 2.7e-137 458.4 19.5 1.6 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 OWF42136.1 - 2.6e-14 53.1 0.0 1.2e-13 51.1 0.0 2.2 1 0 0 1 1 1 1 Death domain CTD_bind PF04818.13 OWF42136.1 - 0.027 15.3 2.2 40 5.1 0.0 4.7 5 0 0 5 5 5 0 RNA polymerase II-binding domain. UAA PF08449.11 OWF42137.1 - 1.3e-86 290.6 25.1 1.5e-86 290.3 25.1 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OWF42137.1 - 2e-07 31.3 25.8 1.5e-06 28.4 10.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family KH_1 PF00013.29 OWF42138.1 - 2.7e-15 55.9 11.6 0.025 14.4 0.0 7.5 7 3 0 7 7 7 4 KH domain LAL_C2 PF18603.1 OWF42138.1 - 3.5e-14 52.7 14.5 0.098 12.8 0.0 7.0 8 0 0 8 8 7 5 L-amino acid ligase C-terminal domain 2 FTR_C PF02741.15 OWF42138.1 - 3.6e-09 36.8 2.4 1.6 8.8 0.0 5.8 6 1 1 7 7 7 3 FTR, proximal lobe Glyco_tran_WecB PF03808.13 OWF42138.1 - 2.1e-08 34.3 4.8 5.1 7.0 0.0 6.8 7 0 0 7 7 7 1 Glycosyl transferase WecB/TagA/CpsF family SMC_Nse1 PF07574.13 OWF42138.1 - 2.8e-08 33.9 10.6 0.83 9.5 0.0 5.9 3 1 2 6 6 6 2 Nse1 non-SMC component of SMC5-6 complex Peptidase_S58 PF03576.14 OWF42138.1 - 5.8e-06 26.0 0.5 9.6 5.6 0.0 5.0 2 1 1 4 4 4 0 Peptidase family S58 PepSY_2 PF13670.6 OWF42138.1 - 7.1e-06 25.9 0.4 4.7 7.3 0.0 4.4 4 0 0 4 4 4 3 Peptidase propeptide and YPEB domain LcrG PF07216.12 OWF42138.1 - 1.7e-05 24.6 7.4 12 5.9 0.0 6.1 7 0 0 7 7 6 0 LcrG protein KH_2 PF07650.17 OWF42138.1 - 0.00038 20.2 38.7 0.85 9.5 0.1 9.7 10 0 0 10 10 10 3 KH domain p25-alpha PF05517.12 OWF42138.1 - 0.0064 16.7 14.3 14 5.8 0.1 5.8 6 0 0 6 6 5 0 p25-alpha DUF1690 PF07956.11 OWF42138.1 - 0.0076 16.7 16.2 5.7 7.4 0.0 5.5 5 1 1 6 6 6 1 Protein of Unknown function (DUF1690) Pdase_M17_N2 PF18295.1 OWF42138.1 - 0.014 15.7 7.1 12 6.1 0.1 4.7 4 0 0 4 4 4 0 M17 aminopeptidase N-terminal domain 2 RNA_pol_I_TF PF04090.12 OWF42138.1 - 0.15 11.6 0.1 0.45 10.0 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase I specific initiation factor Apolipoprotein PF01442.18 OWF42138.1 - 0.18 11.6 11.5 3 7.7 0.5 4.3 2 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain MACPF PF01823.19 OWF42138.1 - 0.22 11.6 2.1 32 4.5 0.0 3.8 2 1 0 4 4 4 0 MAC/Perforin domain BLYB PF05289.11 OWF42138.1 - 0.25 11.6 28.8 6.2 7.1 0.3 5.5 5 0 0 5 5 5 0 Borrelia hemolysin accessory protein T3SchapCesA PF11439.8 OWF42138.1 - 0.81 9.9 23.2 8.6 6.6 0.1 5.7 5 0 0 5 5 5 0 Type III secretion system filament chaperone CesA MIF4G_like_2 PF09090.11 OWF42138.1 - 1 8.8 10.2 18 4.7 1.9 4.3 2 1 0 3 3 3 0 MIF4G like zf-IS66 PF13005.7 OWF42138.1 - 1.1 9.7 5.8 30 5.1 0.1 4.9 5 0 0 5 5 5 0 zinc-finger binding domain of transposase IS66 CENP-F_leu_zip PF10473.9 OWF42138.1 - 5.1 7.1 24.9 11 6.0 0.2 6.2 7 0 0 7 7 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 VSG_B PF13206.6 OWF42138.1 - 5.4 6.2 18.4 8.1 5.6 0.7 4.3 3 1 0 4 4 4 0 Trypanosomal VSG domain Phage_pRha PF09669.10 OWF42138.1 - 7.6 7.2 16.7 61 4.3 1.0 5.5 2 1 2 4 4 4 0 Phage regulatory protein Rha (Phage_pRha) DUF3808 PF10300.9 OWF42139.1 - 2.1e-116 389.5 4.3 3.2e-116 388.9 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 OWF42139.1 - 0.00028 21.5 0.0 0.0019 18.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF42139.1 - 0.00035 21.0 0.0 1.7 9.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF42139.1 - 0.067 12.5 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 MalT-like TPR region TPR_2 PF07719.17 OWF42139.1 - 0.12 12.6 6.7 13 6.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat UQ_con PF00179.26 OWF42140.1 - 1.1e-30 106.2 0.2 6.9e-26 90.6 0.0 3.4 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 OWF42140.1 - 2.9e-05 23.9 0.1 0.00021 21.1 0.0 2.5 2 0 0 2 2 2 1 UEV domain RWD PF05773.22 OWF42140.1 - 3.8e-05 24.0 0.0 0.02 15.2 0.0 3.0 2 0 0 2 2 2 2 RWD domain DUF5117 PF17148.4 OWF42141.1 - 8.4e-05 22.5 3.4 0.34 10.7 0.4 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF5117) Bact_transglu_N PF08379.10 OWF42141.1 - 0.0003 21.6 0.3 7 7.6 0.0 3.4 1 1 3 4 4 4 3 Bacterial transglutaminase-like N-terminal region DUF1336 PF07059.12 OWF42141.1 - 0.0024 18.0 0.1 1.1 9.2 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1336) DUF1964 PF09244.10 OWF42141.1 - 0.016 15.6 0.0 11 6.6 0.0 2.6 1 1 3 4 4 4 0 Domain of unknown function (DUF1964) Mcm10 PF09332.11 OWF42141.1 - 1.8 7.9 10.5 13 5.0 10.5 1.9 1 1 0 1 1 1 0 Mcm10 replication factor MBD_C PF14048.6 OWF42141.1 - 8.1 7.2 15.0 31 5.4 1.4 3.2 1 1 3 4 4 4 0 C-terminal domain of methyl-CpG binding protein 2 and 3 PRP38 PF03371.15 OWF42142.1 - 7.3e-63 211.6 0.5 9.5e-63 211.2 0.5 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 OWF42142.1 - 0.017 15.7 46.2 0.017 15.7 46.2 2.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Cdc6_C PF09079.11 OWF42143.1 - 4.4e-16 58.6 0.0 1.1e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA PF00004.29 OWF42143.1 - 5.4e-15 56.0 0.0 9.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 OWF42143.1 - 4e-12 46.1 0.1 1.5e-11 44.2 0.1 2.0 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 OWF42143.1 - 1.1e-11 45.4 0.0 4.1e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF42143.1 - 3e-11 43.7 0.0 9.2e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 OWF42143.1 - 1.5e-08 34.5 0.0 3.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 BAH domain NACHT PF05729.12 OWF42143.1 - 0.00022 21.2 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 OWF42143.1 - 0.0085 15.8 0.5 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OWF42143.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OWF42143.1 - 0.02 15.2 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OWF42143.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.9 2 1 0 2 2 1 0 AAA domain CX9C PF16860.5 OWF42144.1 - 4.9e-05 23.3 0.6 7.3e-05 22.7 0.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 OWF42144.1 - 0.051 13.8 1.9 0.38 11.0 1.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) CHCH PF06747.13 OWF42144.1 - 0.23 11.6 3.5 1.6 9.0 3.0 2.0 1 1 1 2 2 2 0 CHCH domain RWD PF05773.22 OWF42145.1 - 1.1e-21 77.3 0.0 3.1e-21 75.8 0.0 1.8 1 1 0 1 1 1 1 RWD domain IBR PF01485.21 OWF42145.1 - 2.6e-14 53.2 56.2 3.8e-11 43.1 7.0 5.2 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OWF42145.1 - 0.0056 16.6 11.1 0.0056 16.6 11.1 5.2 4 2 2 6 6 6 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF42145.1 - 0.0081 16.5 11.3 0.0081 16.5 11.3 5.2 4 1 0 4 4 4 1 Ring finger domain zf-RING_7 PF02591.15 OWF42145.1 - 0.19 11.9 17.5 7.6 6.8 4.4 5.5 4 1 0 4 4 4 0 C4-type zinc ribbon domain Alg6_Alg8 PF03155.15 OWF42146.1 - 3.4e-146 488.0 31.2 4.2e-146 487.7 31.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DEAD PF00270.29 OWF42147.1 - 3.6e-54 183.2 0.0 5.5e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 OWF42147.1 - 2.2e-34 116.0 50.7 6e-07 29.3 5.1 5.6 5 0 0 5 5 5 5 Zinc knuckle Helicase_C PF00271.31 OWF42147.1 - 2.1e-32 111.8 0.0 6.2e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC_3 PF13917.6 OWF42147.1 - 2.3e-13 49.9 27.0 0.035 14.1 0.0 5.8 6 0 0 6 6 6 5 Zinc knuckle ResIII PF04851.15 OWF42147.1 - 8.1e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_2 PF13696.6 OWF42147.1 - 0.00072 19.3 38.9 0.0072 16.1 1.9 5.3 5 0 0 5 5 5 3 Zinc knuckle CMS1 PF14617.6 OWF42147.1 - 0.0011 18.3 0.2 0.0031 16.9 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit HEM4 PF02602.15 OWF42147.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD UTP25 PF06862.12 OWF42147.1 - 0.03 13.1 0.0 0.25 10.1 0.0 2.2 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OWF42147.1 - 0.092 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-CCHC_5 PF14787.6 OWF42147.1 - 1.3 8.8 36.2 3.6 7.4 3.1 5.4 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger SHIPPO-rpt PF07004.12 OWF42148.1 - 1.6e-12 47.7 18.0 0.11 13.4 0.3 7.5 7 0 0 7 7 7 6 Sperm-tail PG-rich repeat Nipped-B_C PF12830.7 OWF42149.1 - 8.1e-65 218.3 8.2 2.8e-63 213.3 3.1 4.1 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 OWF42149.1 - 7.9e-12 45.3 1.7 2.5e-11 43.7 0.0 2.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 OWF42149.1 - 0.00021 21.3 1.1 12 6.5 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 OWF42149.1 - 0.00022 21.3 6.4 0.4 10.7 0.1 4.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OWF42149.1 - 0.00065 20.0 0.0 11 6.4 0.0 5.0 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 OWF42149.1 - 0.034 14.7 0.0 49 4.6 0.0 4.8 4 1 0 4 4 4 0 HEAT-like repeat RGS PF00615.19 OWF42149.1 - 1.1 9.6 14.2 0.62 10.4 1.2 4.1 3 0 0 3 3 3 0 Regulator of G protein signaling domain SCP2 PF02036.17 OWF42150.1 - 6.2e-24 84.4 0.5 1.3e-23 83.4 0.5 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_N PF00108.23 OWF42150.1 - 1.1e-21 77.4 0.2 1.3e-20 73.9 0.2 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OWF42150.1 - 1.3e-13 50.7 0.5 2.5e-10 40.0 0.0 3.2 2 1 1 3 3 3 2 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OWF42150.1 - 2.8e-05 23.8 0.5 0.0047 16.5 0.2 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OWF42150.1 - 5.9e-05 22.8 1.1 0.0031 17.3 0.0 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 OWF42150.1 - 0.0028 16.4 0.0 0.0084 14.8 0.0 1.7 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Alkyl_sulf_C PF14864.6 OWF42150.1 - 0.027 14.7 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal DUF2181 PF10223.9 OWF42151.1 - 3.4e-66 223.2 0.1 4.5e-66 222.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Myosin_TH1 PF06017.13 OWF42151.1 - 0.018 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding DUF4945 PF16303.5 OWF42151.1 - 0.097 12.6 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) Importin_rep_3 PF18806.1 OWF42152.1 - 6.1e-26 90.3 0.1 2.3e-25 88.4 0.1 2.1 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep PF18773.1 OWF42152.1 - 4.3e-23 80.7 2.4 1.1e-22 79.4 2.4 1.8 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 OWF42152.1 - 3.6e-21 75.8 11.3 8.2e-21 74.6 0.7 5.2 4 2 2 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 OWF42152.1 - 2.6e-08 33.7 0.7 1.2e-07 31.6 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep_2 PF18786.1 OWF42152.1 - 4.1e-06 26.5 1.5 6.4e-06 25.9 0.2 2.1 2 0 0 2 2 2 1 Importin 13 repeat FANCI_S4 PF14678.6 OWF42152.1 - 0.012 14.7 0.1 0.097 11.8 0.0 2.4 2 1 1 3 3 3 0 FANCI solenoid 4 OAM_alpha PF16552.5 OWF42152.1 - 0.041 13.8 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 D-ornithine 4,5-aminomutase alpha-subunit CLASP_N PF12348.8 OWF42152.1 - 0.069 12.7 2.6 0.34 10.5 0.2 3.4 5 0 0 5 5 5 0 CLASP N terminal CENP-K PF11802.8 OWF42153.1 - 3.4e-50 171.1 6.0 4.4e-50 170.7 6.0 1.0 1 0 0 1 1 1 1 Centromere-associated protein K Prominin PF05478.11 OWF42153.1 - 0.022 12.7 2.5 0.025 12.6 2.5 1.1 1 0 0 1 1 1 0 Prominin DUF5082 PF16888.5 OWF42153.1 - 0.19 12.0 5.1 0.063 13.6 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TMPIT PF07851.13 OWF42153.1 - 0.55 9.4 1.8 0.99 8.6 1.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein EIF_2_alpha PF07541.12 OWF42154.1 - 3.2e-37 127.2 0.2 5.9e-37 126.3 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OWF42154.1 - 1.4e-16 60.6 1.6 1.4e-16 60.6 0.3 1.7 2 0 0 2 2 2 1 S1 RNA binding domain EIF_2_alpha PF07541.12 OWF42155.1 - 1.9e-29 102.1 0.0 5.5e-29 100.6 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OWF42155.1 - 6.2e-08 32.9 0.5 1.2e-07 31.9 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain DUF4453 PF14627.6 OWF42155.1 - 0.04 14.0 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) zf-RING_UBOX PF13445.6 OWF42156.1 - 4.4e-09 36.2 7.9 4.4e-09 36.2 7.9 4.3 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF42156.1 - 3.4e-08 33.5 8.8 1.8e-07 31.2 8.8 2.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF42156.1 - 1.8e-07 30.9 11.9 1.8e-07 30.9 11.9 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF42156.1 - 1.3e-05 25.4 12.7 1.3e-05 25.4 12.7 3.8 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF42156.1 - 2.4e-05 24.1 9.4 2.4e-05 24.1 9.4 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF42156.1 - 3.8e-05 23.6 13.5 3.8e-05 23.6 13.5 3.6 4 0 0 4 4 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF42156.1 - 0.00019 21.2 13.8 0.00019 21.2 13.8 4.3 4 2 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF42156.1 - 0.00054 20.1 5.8 0.00054 20.1 5.8 3.1 2 1 0 2 2 1 1 B-box zinc finger Prok-RING_4 PF14447.6 OWF42156.1 - 0.0085 15.9 8.1 0.0085 15.9 8.1 3.4 4 1 0 4 4 3 1 Prokaryotic RING finger family 4 NHL PF01436.21 OWF42156.1 - 0.039 14.0 0.3 28 5.0 0.1 3.4 3 0 0 3 3 3 0 NHL repeat zf-Nse PF11789.8 OWF42156.1 - 0.097 12.5 11.8 0.27 11.1 9.1 2.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 OWF42156.1 - 0.27 11.3 10.1 3.9 7.6 4.2 2.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger H-kinase_dim PF02895.14 OWF42156.1 - 0.33 11.4 4.5 1.9 9.0 0.1 2.7 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Golgin_A5 PF09787.9 OWF42156.1 - 0.39 10.1 11.3 0.61 9.5 11.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-Q PF13094.6 OWF42156.1 - 1.1 9.4 11.1 0.13 12.4 3.8 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.11 OWF42156.1 - 2.7 6.8 12.7 4 6.2 12.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein K-box PF01486.17 OWF42156.1 - 3.6 7.8 12.8 0.073 13.3 3.4 2.4 2 0 0 2 2 2 0 K-box region zf-RING_4 PF14570.6 OWF42156.1 - 7.8 6.4 11.6 2.7 7.9 7.1 2.7 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain C1q PF00386.21 OWF42157.1 - 7.2e-06 26.2 0.0 7.3e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 C1q domain SH3_9 PF14604.6 OWF42157.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain UCH PF00443.29 OWF42160.1 - 1.6e-63 214.6 2.3 2.9e-63 213.8 2.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF42160.1 - 2e-20 73.6 4.0 3.1e-19 69.7 4.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OWF42161.1 - 1.9e-10 40.3 0.1 3.7e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family BAG PF02179.16 OWF42161.1 - 5.3e-08 33.2 3.6 1.1e-07 32.2 2.3 2.0 2 1 0 2 2 2 1 BAG domain TBK1_ULD PF18396.1 OWF42161.1 - 0.00019 21.3 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OWF42161.1 - 0.00042 20.6 0.5 0.0011 19.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 OWF42161.1 - 0.0098 16.3 0.1 0.08 13.4 0.1 2.4 1 1 1 2 2 2 1 Ubiquitin-like domain KLRAQ PF10205.9 OWF42161.1 - 0.032 14.5 0.5 3.4 8.0 0.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Annexin_like PF18411.1 OWF42161.1 - 0.056 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Annexin-like domain Med21 PF11221.8 OWF42161.1 - 0.091 13.0 0.7 3.4 7.9 0.4 2.5 1 1 1 2 2 2 0 Subunit 21 of Mediator complex MRP-S23 PF10484.9 OWF42161.1 - 0.17 12.1 0.3 0.43 10.9 0.0 1.7 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 DUF1825 PF08855.10 OWF42161.1 - 0.19 11.7 2.8 5.6 6.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1825) DHC_N1 PF08385.12 OWF42162.1 - 1.1e-168 562.4 6.3 1.1e-168 562.4 6.3 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OWF42162.1 - 6.6e-146 485.4 0.0 5.3e-145 482.5 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF42162.1 - 8.6e-123 410.4 5.7 8.6e-123 410.4 5.7 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF42162.1 - 3.7e-95 318.7 0.4 4.2e-94 315.2 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF42162.1 - 7.1e-93 310.7 0.0 1.7e-92 309.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF42162.1 - 6e-85 283.9 2.3 2.2e-84 282.0 0.4 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF42162.1 - 1.4e-65 220.2 0.6 1.6e-60 203.7 0.1 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF42162.1 - 2.2e-53 180.4 0.0 5.8e-53 179.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF42162.1 - 2.7e-43 148.3 6.8 7.5e-43 146.9 6.8 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF42162.1 - 3.4e-39 133.6 0.0 2.2e-38 131.0 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF42162.1 - 1.6e-26 92.9 1.6 5.9e-24 84.6 0.3 3.5 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OWF42162.1 - 9.2e-18 64.3 0.0 6.9e-17 61.5 0.0 2.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 OWF42162.1 - 9.7e-17 61.3 0.0 0.00013 22.0 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.29 OWF42162.1 - 8.5e-05 23.0 0.1 2 8.9 0.0 4.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF42162.1 - 0.033 14.5 3.5 31 4.8 0.0 5.0 5 0 0 5 5 5 0 AAA domain AAA_18 PF13238.6 OWF42162.1 - 0.17 12.5 0.1 32 5.1 0.0 4.3 4 0 0 4 4 4 0 AAA domain MscS_porin PF12795.7 OWF42162.1 - 0.26 10.8 13.8 6.5 6.2 4.4 4.0 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 OWF42162.1 - 1.9 7.8 9.9 1.1 8.5 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YtxH PF12732.7 OWF42162.1 - 6 7.5 5.8 1.9e+02 2.7 0.1 4.0 2 0 0 2 2 2 0 YtxH-like protein Fez1 PF06818.15 OWF42162.1 - 8.9 6.7 9.0 10 6.5 0.1 3.1 2 0 0 2 2 2 0 Fez1 7TM_GPCR_Srw PF10324.9 OWF42163.1 - 4.8e-19 68.8 25.7 9.1e-19 67.9 25.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4252 PF14060.6 OWF42164.1 - 0.069 13.1 0.0 1.6 8.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) 7tm_1 PF00001.21 OWF42165.1 - 1.7e-06 27.6 4.5 2.1e-06 27.3 4.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF42165.1 - 0.003 17.0 2.6 0.0041 16.5 2.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF42165.1 - 0.029 14.1 2.6 0.038 13.7 2.6 1.1 1 0 0 1 1 1 0 Olfactory receptor Cyclin_N PF00134.23 OWF42166.1 - 7.3e-28 96.9 0.5 2.5e-26 91.9 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF42166.1 - 3.8e-21 75.4 0.1 1.1e-20 73.9 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain F-box-like PF12937.7 OWF42166.1 - 6.3e-05 22.8 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF42166.1 - 0.00091 19.0 0.4 0.0042 16.9 0.2 2.2 2 0 0 2 2 2 1 F-box domain Sel1 PF08238.12 OWF42166.1 - 0.09 13.5 0.1 7.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Sel1 repeat Tubulin PF00091.25 OWF42167.1 - 8.3e-68 228.5 0.0 1.1e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF42167.1 - 3.6e-52 175.8 0.0 5.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OWF42167.1 - 0.00094 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 OWF42168.1 - 3.3e-19 69.9 0.0 3.6e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF42169.1 - 1.5e-51 173.8 0.0 2.5e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 OWF42169.1 - 2.6e-42 145.3 0.0 3.9e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 OWF42169.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Peptidase_C54 PF03416.19 OWF42170.1 - 2.7e-103 345.2 0.0 3.6e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Methyltransf_22 PF13383.6 OWF42171.1 - 1e-21 77.7 1.1 1.2e-21 77.4 1.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF42171.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 OWF42172.1 - 3.2e-05 24.0 0.0 0.001 19.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase FkbM domain TPR_1 PF00515.28 OWF42174.1 - 1.2e-10 40.7 4.7 0.0015 18.3 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF42174.1 - 1e-09 37.8 5.2 0.025 14.8 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42174.1 - 1.8e-09 37.0 9.9 0.017 15.2 0.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat S1 PF00575.23 OWF42174.1 - 5.2e-07 29.9 0.7 2.9e-05 24.3 0.7 2.5 1 1 0 1 1 1 1 S1 RNA binding domain TPR_11 PF13414.6 OWF42174.1 - 1.3e-06 28.0 9.6 7.6e-05 22.3 0.6 3.6 3 1 1 4 4 3 2 TPR repeat TPR_14 PF13428.6 OWF42174.1 - 2.7e-05 24.6 1.0 0.37 11.7 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF42174.1 - 0.00013 22.5 0.2 0.94 10.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF42174.1 - 0.00044 20.3 0.1 0.0027 17.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF42174.1 - 0.0033 17.7 5.1 0.39 11.1 4.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF42174.1 - 0.0041 17.4 3.3 0.05 14.0 0.8 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF42174.1 - 0.043 14.3 6.1 0.23 12.0 0.9 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 OWF42174.1 - 0.045 13.0 4.8 0.12 11.5 0.5 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF42174.1 - 0.2 11.9 4.7 6.9 7.0 2.8 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OWF42174.1 - 6.6 7.6 6.1 36 5.3 0.0 3.7 3 1 0 3 3 2 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 OWF42175.1 - 1.1e-10 40.8 4.6 1.1e-10 40.8 4.6 1.4 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family FTR1 PF03239.14 OWF42175.1 - 0.0052 16.0 0.9 0.0088 15.3 0.9 1.3 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2946 PF11162.8 OWF42175.1 - 0.085 13.5 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) FAM176 PF14851.6 OWF42175.1 - 0.28 10.8 1.2 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 FAM176 family LrgB PF04172.16 OWF42175.1 - 0.8 9.2 4.6 0.55 9.7 1.4 2.2 2 1 0 2 2 2 0 LrgB-like family FtsH_ext PF06480.15 OWF42175.1 - 1.1 9.7 0.1 1.1 9.7 0.1 2.6 3 0 0 3 3 3 0 FtsH Extracellular FtsX PF02687.21 OWF42175.1 - 2.1 8.9 12.7 0.99 9.9 2.9 2.5 2 1 0 2 2 2 0 FtsX-like permease family IBR PF01485.21 OWF42177.1 - 2.6e-14 53.2 26.3 1.2e-11 44.7 6.7 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OWF42177.1 - 0.00031 20.6 9.3 0.00031 20.6 9.3 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF42177.1 - 0.00038 20.4 7.4 0.00038 20.4 7.4 4.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF42177.1 - 0.00057 20.2 8.2 0.00057 20.2 8.2 4.5 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 OWF42177.1 - 0.0011 18.8 5.1 0.0011 18.8 5.1 4.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF42177.1 - 0.0059 16.5 6.6 0.0059 16.5 6.6 3.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_2 PF14445.6 OWF42177.1 - 0.0062 16.7 3.1 0.0062 16.7 3.1 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 2 zf-C3HC4_4 PF15227.6 OWF42177.1 - 0.35 11.1 36.9 1.7 8.9 2.9 4.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF5326 PF17260.2 OWF42178.1 - 2.5 8.3 7.2 24 5.1 0.4 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5326) SIS_2 PF13580.6 OWF42179.1 - 0.00063 19.8 4.9 49 3.9 0.0 6.0 1 1 3 6 6 6 0 SIS domain HTH_34 PF13601.6 OWF42179.1 - 0.0009 19.4 12.6 3.8 7.8 0.1 6.6 1 1 8 9 9 9 2 Winged helix DNA-binding domain PH_5 PF15405.6 OWF42179.1 - 0.0047 17.0 8.0 2.3 8.3 0.7 3.4 1 1 2 3 3 3 3 Pleckstrin homology domain C2-set_2 PF08205.12 OWF42179.1 - 0.27 11.3 15.2 6.8 6.8 0.4 4.1 1 1 4 5 5 5 0 CD80-like C2-set immunoglobulin domain POLO_box PF00659.18 OWF42179.1 - 1.6 9.0 13.5 1.8e+04 -5.4 13.4 4.8 1 1 0 1 1 1 0 POLO box duplicated region cNMP_binding PF00027.29 OWF42181.1 - 2.6e-20 72.3 0.1 0.00017 21.6 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain GalP_UDP_transf PF01087.22 OWF42181.1 - 0.029 14.8 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain nos_propeller_2 PF18793.1 OWF42182.1 - 4.1e-05 23.8 0.0 21 5.5 0.0 5.9 2 2 6 9 9 9 0 Nitrous oxide reductase propeller repeat 2 RE_Bpu10I PF09549.10 OWF42182.1 - 0.00047 19.8 1.4 2.3 7.8 0.1 4.0 2 2 1 4 4 4 1 Bpu10I restriction endonuclease Tsi6 PF18660.1 OWF42182.1 - 0.0058 16.7 0.1 24 5.1 0.0 4.4 3 3 0 3 3 3 0 Tsi6 RPM2 PF08579.11 OWF42182.1 - 0.017 15.5 2.0 6.1 7.3 0.1 3.9 1 1 3 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) DegT_DnrJ_EryC1 PF01041.17 OWF42182.1 - 0.029 13.7 0.1 4.1 6.6 0.0 3.1 1 1 3 4 4 4 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ephrin_rec_like PF07699.13 OWF42182.1 - 0.03 14.1 3.2 37 4.2 0.0 5.6 7 0 0 7 7 7 0 Putative ephrin-receptor like DUF2753 PF10952.8 OWF42182.1 - 0.031 14.4 8.3 4 7.6 0.2 4.5 1 1 3 6 6 6 0 Protein of unknown function (DUF2753) DUF2336 PF10098.9 OWF42182.1 - 0.069 12.6 0.6 26 4.1 0.0 4.0 2 1 3 5 5 5 0 Uncharacterised protein conserved in bacteria (DUF2336) Endotoxin_M PF00555.19 OWF42182.1 - 0.45 10.5 30.0 36 4.3 1.1 9.7 6 3 2 8 8 8 0 delta endotoxin CID_GANP PF16766.5 OWF42182.1 - 0.99 9.7 12.9 38 4.6 0.4 5.5 5 3 1 6 6 6 0 Binding region of GANP to ENY2 QSOX_Trx1 PF18108.1 OWF42183.1 - 0.05 13.8 0.2 14 5.9 0.0 2.7 1 1 0 2 2 2 0 QSOX Trx-like domain SPATA48 PF15073.6 OWF42184.1 - 0.00011 22.4 2.1 2.8 8.2 0.1 3.1 1 1 2 3 3 3 3 Spermatogenesis-associated protein 48 TcA_RBD PF18518.1 OWF42184.1 - 0.00015 22.1 0.0 0.11 12.8 0.0 3.5 1 1 3 4 4 4 2 TcA receptor binding domain zf-C5HC2 PF02928.16 OWF42184.1 - 0.021 15.2 10.4 7.9 7.0 0.1 4.6 1 1 6 7 7 7 0 C5HC2 zinc finger L71 PF02448.15 OWF42184.1 - 0.55 10.7 4.5 29 5.2 0.1 3.3 1 1 0 3 3 3 0 L71 family HECT PF00632.25 OWF42185.1 - 2.9e-76 256.9 0.7 2.9e-76 256.9 0.7 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 OWF42185.1 - 3.4e-12 47.1 1.9 5.7e-09 36.7 0.2 2.6 2 0 0 2 2 2 2 Filamin/ABP280 repeat SAM_2 PF07647.17 OWF42185.1 - 0.0019 18.3 0.0 0.019 15.1 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) VP4_helical PF17478.2 OWF42185.1 - 0.054 12.9 0.1 0.095 12.1 0.1 1.3 1 0 0 1 1 1 0 Rotavirus VP4 helical domain SAM_1 PF00536.30 OWF42185.1 - 0.11 12.9 0.2 0.38 11.2 0.1 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) CAP_GLY PF01302.25 OWF42186.1 - 3.5e-18 65.4 0.8 6.3e-18 64.6 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 OWF42186.1 - 1.9e-07 30.7 15.9 3e-05 23.7 6.0 4.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 OWF42186.1 - 3.2e-07 30.6 22.6 0.0025 18.2 2.0 4.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF42186.1 - 4.6e-07 29.5 5.5 1.9e-06 27.5 1.6 2.5 1 1 2 3 3 3 2 Leucine-rich repeat Ubiquitin_2 PF14560.6 OWF42186.1 - 1.4e-05 25.5 0.1 4e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain UN_NPL4 PF11543.8 OWF42186.1 - 0.0012 19.3 0.0 0.0037 17.7 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PB1 PF00564.24 OWF42186.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain ubiquitin PF00240.23 OWF42186.1 - 0.017 14.9 0.3 0.063 13.0 0.3 2.0 1 1 0 1 1 1 0 Ubiquitin family Sulfatase PF00884.23 OWF42187.1 - 1.2e-50 172.7 0.0 1.6e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF42187.1 - 0.00028 20.6 0.0 0.0024 17.5 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OWF42187.1 - 0.00038 21.2 0.0 0.00068 20.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF2304 PF10066.9 OWF42187.1 - 0.064 13.5 0.4 0.14 12.4 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) MFS_1 PF07690.16 OWF42188.1 - 1.9e-06 27.1 1.5 1.9e-06 27.1 1.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF42188.1 - 0.00013 21.0 4.0 0.00013 21.0 4.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter TMEM100 PF16311.5 OWF42188.1 - 0.0072 15.9 0.3 0.018 14.6 0.3 1.7 1 0 0 1 1 1 1 Transmembrane protein 100 MCM PF00493.23 OWF42189.1 - 5.5e-99 329.8 0.0 9.4e-99 329.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OWF42189.1 - 2.2e-39 134.2 0.6 4e-39 133.3 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OWF42189.1 - 1.5e-27 95.8 0.3 4e-27 94.5 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OWF42189.1 - 2.7e-19 69.7 0.4 8.1e-19 68.1 0.4 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OWF42189.1 - 7.2e-07 28.8 0.1 0.00043 19.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF42189.1 - 0.00025 21.1 0.0 0.00063 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OWF42189.1 - 0.0032 17.3 0.0 0.009 15.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OWF42189.1 - 0.014 15.2 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4111 PF13427.6 OWF42189.1 - 0.059 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) TrmB PF01978.19 OWF42189.1 - 0.22 11.4 2.4 0.26 11.2 0.5 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Ribosomal_60s PF00428.19 OWF42191.1 - 0.011 16.3 3.1 0.031 14.9 3.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein BSP_II PF05432.11 OWF42191.1 - 0.013 15.2 3.8 0.017 14.8 3.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4611 PF15387.6 OWF42191.1 - 0.038 14.2 3.2 0.13 12.5 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HSA PF07529.13 OWF42191.1 - 9.6 6.6 9.3 2.2 8.6 5.7 1.8 2 0 0 2 2 2 0 HSA Mito_fiss_reg PF05308.11 OWF42192.1 - 0.08 13.0 2.0 0.2 11.7 2.0 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 OWF42192.1 - 0.52 9.8 3.7 1.1 8.7 3.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 OWF42192.1 - 2.9 8.0 8.8 5.9 7.0 8.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pinin_SDK_N PF04697.13 OWF42193.1 - 3.9e-39 134.4 4.7 3.9e-39 134.4 4.7 4.4 3 1 1 5 5 5 1 pinin/SDK conserved region Pinin_SDK_memA PF04696.13 OWF42193.1 - 7.8e-30 103.6 15.6 7.8e-30 103.6 15.6 4.2 1 1 2 3 3 3 1 pinin/SDK/memA/ protein conserved region TRAPP PF04051.16 OWF42194.1 - 6.1e-48 162.3 0.1 6.8e-48 162.1 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Na_Pi_cotrans PF02690.15 OWF42195.1 - 6.4e-39 133.2 23.1 8.6e-25 87.5 7.0 2.8 2 1 0 2 2 2 2 Na+/Pi-cotransporter Adeno_E3_14_5 PF04834.12 OWF42195.1 - 0.22 12.1 1.5 19 5.8 0.4 2.8 2 0 0 2 2 2 0 Early E3 14.5 kDa protein Na_Pi_cotrans PF02690.15 OWF42196.1 - 4.5e-38 130.5 22.1 8e-25 87.6 5.7 2.8 2 1 0 2 2 2 2 Na+/Pi-cotransporter Aminotran_5 PF00266.19 OWF42197.1 - 3.8e-25 88.6 0.0 4.9e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V UPF0020 PF01170.18 OWF42197.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Proteasome PF00227.26 OWF42198.1 - 2.4e-53 180.5 0.1 2.9e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OWF42198.1 - 3.6e-12 45.7 0.1 5.7e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LRR_8 PF13855.6 OWF42199.1 - 8.3e-20 70.3 10.4 1.8e-12 46.9 2.6 3.6 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OWF42199.1 - 1e-13 51.2 8.4 8.2e-06 26.1 0.9 4.4 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF42199.1 - 8.2e-08 31.8 8.8 0.48 11.2 0.2 6.7 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 OWF42199.1 - 1.1e-05 25.1 10.9 0.59 10.3 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_5 PF13306.6 OWF42199.1 - 0.0047 16.9 1.0 0.018 15.0 0.1 2.4 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF42199.1 - 0.033 13.7 0.2 0.058 12.9 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat DUF4614 PF15391.6 OWF42201.1 - 3 7.8 6.2 2.7 7.9 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) PTPlike_phytase PF14566.6 OWF42203.1 - 5.6e-36 124.0 0.2 1.1e-31 110.0 0.1 2.5 2 0 0 2 2 2 2 Inositol hexakisphosphate DUF4715 PF15835.5 OWF42203.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) DUF1911 PF08929.10 OWF42204.1 - 0.042 14.7 0.6 0.053 14.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Amino_oxidase PF01593.24 OWF42205.1 - 3e-18 66.4 0.0 2.5e-14 53.5 0.0 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF42205.1 - 1.2e-11 44.6 0.1 2.2e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF42205.1 - 0.00062 19.4 0.5 0.0044 16.7 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF42205.1 - 0.0045 16.3 2.0 0.082 12.1 1.9 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF42205.1 - 0.025 15.1 0.3 1.9 9.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Snapin_Pallidin PF14712.6 OWF42205.1 - 0.12 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Snapin/Pallidin FAD_binding_3 PF01494.19 OWF42205.1 - 0.23 10.6 0.2 0.56 9.4 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain DUF3456 PF11938.8 OWF42206.1 - 1.2e-07 32.4 1.3 5.6e-06 26.9 0.2 2.7 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP RabGAP-TBC PF00566.18 OWF42207.1 - 1.6e-46 158.7 1.6 2.3e-46 158.1 1.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 OWF42207.1 - 1.3e-33 115.8 0.1 3.3e-33 114.5 0.1 1.7 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 OWF42207.1 - 7.1e-12 44.7 0.1 1.5e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF42207.1 - 3.7e-10 39.5 0.0 9.4e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF42207.1 - 2.9e-09 36.5 0.0 5.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AlcCBM31 PF11606.8 OWF42208.1 - 0.072 13.3 0.3 1.3 9.3 0.1 2.1 2 0 0 2 2 2 0 Family 31 carbohydrate binding protein A_amylase_inhib PF01356.19 OWF42208.1 - 0.09 12.8 16.5 3.1 7.9 0.8 4.9 1 1 3 5 5 5 0 Alpha amylase inhibitor DUF2972 PF11186.8 OWF42208.1 - 0.94 9.4 3.8 11 5.9 3.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) A_amylase_inhib PF01356.19 OWF42209.1 - 0.0034 17.3 16.8 9.5 6.3 0.1 5.6 1 1 6 7 7 7 7 Alpha amylase inhibitor MP PF01107.18 OWF42209.1 - 0.011 15.3 3.2 13 5.3 0.1 3.5 1 1 4 5 5 5 0 Viral movement protein (MP) DUF2972 PF11186.8 OWF42209.1 - 0.18 11.7 4.1 0.66 9.9 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) Calmodulin_bind PF07887.11 OWF42209.1 - 0.26 10.5 1.6 2.8 7.2 0.1 2.2 1 1 1 2 2 2 0 Calmodulin binding protein-like Mannosyl_trans3 PF11051.8 OWF42209.1 - 0.52 9.6 2.9 11 5.3 0.9 2.9 1 1 2 3 3 3 0 Mannosyltransferase putative DUF840 PF05801.11 OWF42209.1 - 1.2 9.2 6.1 2.8 8.0 1.5 2.3 1 1 2 3 3 3 0 Lagovirus protein of unknown function (DUF840) C6_DPF PF10170.9 OWF42209.1 - 1.7 9.0 9.0 11 6.5 0.9 3.1 1 1 2 3 3 3 0 Cysteine-rich domain IRK PF01007.20 OWF42209.1 - 6.6 6.5 7.2 8.4 6.2 0.5 2.8 1 1 2 3 3 3 0 Inward rectifier potassium channel transmembrane domain Cu-binding_MopE PF11617.8 OWF42209.1 - 7.8 6.8 32.8 31 4.8 0.1 6.9 8 0 0 8 8 8 0 Putative metal-binding motif DUF4115 PF13464.6 OWF42210.1 - 0.4 10.9 17.9 27 5.1 0.5 5.7 1 1 5 7 7 7 0 Domain of unknown function (DUF4115) Pkinase PF00069.25 OWF42211.1 - 1.6e-66 224.4 0.0 1.9e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42211.1 - 2.4e-38 131.9 0.0 3.2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF42211.1 - 3.1e-05 23.4 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF42211.1 - 4.2e-05 23.0 0.0 5.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF42211.1 - 0.00035 19.6 0.1 0.00054 19.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF42211.1 - 0.063 13.2 0.4 0.19 11.6 0.2 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop52 PF05997.12 OWF42212.1 - 2.3e-64 217.2 5.7 4.6e-64 216.2 5.7 1.5 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF1877 PF08974.10 OWF42212.1 - 2.4 8.2 5.6 0.85 9.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1877) Pou PF00157.17 OWF42213.1 - 2.1e-36 123.7 0.1 2.1e-36 123.7 0.1 2.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 OWF42213.1 - 2e-17 62.8 0.9 2e-17 62.8 0.9 2.5 2 0 0 2 2 1 1 Homeodomain CNDH2_N PF06278.11 OWF42213.1 - 0.013 15.7 3.1 0.013 15.7 3.1 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FAM176 PF14851.6 OWF42213.1 - 0.15 11.8 2.2 0.33 10.6 2.2 1.5 1 0 0 1 1 1 0 FAM176 family TRAPPC-Trs85 PF12739.7 OWF42213.1 - 0.17 10.9 8.7 0.29 10.0 8.7 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF4471 PF14740.6 OWF42213.1 - 0.7 9.1 6.5 1.5 8.0 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Connexin PF00029.19 OWF42213.1 - 0.94 9.2 5.9 1.9 8.2 5.9 1.4 1 0 0 1 1 1 0 Connexin TraV PF09676.10 OWF42213.1 - 1.2 10.1 28.3 3.7 8.5 18.4 2.8 3 0 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) Tim54 PF11711.8 OWF42213.1 - 1.5 7.5 15.2 3 6.5 15.2 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 OWF42213.1 - 1.7 7.5 9.2 3.2 6.6 9.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4834 PF16118.5 OWF42213.1 - 9.8 7.2 19.4 2.1 9.3 13.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) HSP70 PF00012.20 OWF42214.1 - 1.1e-87 294.7 8.0 1.1e-87 294.7 8.0 3.0 2 1 1 3 3 3 2 Hsp70 protein FGGY_C PF02782.16 OWF42214.1 - 0.012 15.3 0.2 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1657 PF07870.11 OWF42214.1 - 0.19 11.6 7.7 7.7 6.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) EF-hand_1 PF00036.32 OWF42215.1 - 2.1e-13 48.7 3.9 0.0016 17.8 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OWF42215.1 - 3.9e-13 49.6 4.8 1.3e-08 35.2 3.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF42215.1 - 2.2e-10 39.6 5.8 0.0033 17.2 0.5 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OWF42215.1 - 2.8e-08 33.5 6.5 0.0058 16.4 0.4 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF42215.1 - 0.012 15.1 3.4 0.2 11.2 0.5 3.1 3 0 0 3 3 3 0 EF hand EF-hand_9 PF14658.6 OWF42215.1 - 0.17 12.2 1.9 6.6 7.1 0.2 2.6 3 0 0 3 3 3 0 EF-hand domain CUB PF00431.20 OWF42216.1 - 2.2e-24 85.9 1.0 1e-12 48.3 0.1 2.6 2 0 0 2 2 2 2 CUB domain DUF4006 PF13179.6 OWF42216.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) V-SNARE_C PF12352.8 OWF42216.1 - 0.62 10.4 2.2 1e+02 3.3 0.1 3.3 1 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus EamA PF00892.20 OWF42217.1 - 7e-12 45.7 26.8 6e-07 29.7 7.6 2.8 2 2 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 OWF42217.1 - 8.9e-10 38.6 19.7 1.7e-08 34.3 19.7 2.1 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 OWF42217.1 - 1.1e-06 27.8 7.6 1.1e-06 27.8 7.6 2.3 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 OWF42217.1 - 1.6e-06 27.7 8.9 2.7e-06 27.0 8.9 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 OWF42217.1 - 5.5e-06 25.8 1.6 5.5e-06 25.8 1.6 2.0 2 1 0 2 2 2 1 Nucleotide-sugar transporter TMEM234 PF10639.9 OWF42217.1 - 0.015 15.4 4.8 0.95 9.5 0.3 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF1011 PF06237.12 OWF42218.1 - 1.4 9.2 3.8 4.9 7.5 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) DUF5429 PF17494.2 OWF42219.1 - 1.7 8.8 6.3 34 4.6 0.1 4.0 3 1 0 4 4 4 0 Family of unknown function (DUF5429) NLE PF08154.12 OWF42219.1 - 2.1 9.0 13.8 2.4e+02 2.3 0.2 6.8 3 3 2 5 5 5 0 NLE (NUC135) domain Alk_phosphatase PF00245.20 OWF42220.1 - 7.7e-129 430.3 0.0 8.9e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF42220.1 - 0.0014 18.0 0.1 0.0018 17.7 0.1 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 OWF42221.1 - 1.8e-118 396.1 0.6 2e-118 395.9 0.6 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF42221.1 - 3.1e-05 23.5 0.1 5.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily COR PF16095.5 OWF42222.1 - 2.8e-11 43.6 0.2 8.7e-11 42.0 0.2 1.9 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF42222.1 - 5.2e-07 29.9 0.4 2.4e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF42222.1 - 0.0001 22.4 0.0 0.004 17.3 0.0 2.7 3 0 0 3 3 3 1 Death domain Ras PF00071.22 OWF42222.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Ras family RGS PF00615.19 OWF42223.1 - 0.025 14.8 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain RGS PF00615.19 OWF42224.1 - 4.3e-24 85.1 3.3 5.4e-12 46.0 0.3 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Roc PF08477.13 OWF42225.1 - 2e-10 40.9 0.5 2.3e-06 27.8 0.0 3.1 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF42225.1 - 6.6e-10 39.1 0.3 1.6e-09 37.9 0.3 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Death PF00531.22 OWF42225.1 - 0.00026 21.1 0.0 0.01 16.0 0.0 2.6 2 0 0 2 2 2 1 Death domain Arf PF00025.21 OWF42225.1 - 0.00064 19.2 0.1 0.031 13.7 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family Ras PF00071.22 OWF42225.1 - 0.0047 16.6 0.0 0.042 13.4 0.0 2.3 2 0 0 2 2 2 1 Ras family PduV-EutP PF10662.9 OWF42225.1 - 0.023 14.4 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OWF42225.1 - 0.11 12.7 0.1 0.43 10.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OWF42225.1 - 0.12 12.7 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain His_Phos_1 PF00300.22 OWF42227.1 - 8.7e-22 77.8 0.1 9.6e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 OWF42228.1 - 1.8e-70 237.4 0.0 3.9e-70 236.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42228.1 - 3.5e-28 98.6 0.0 5.9e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 OWF42228.1 - 1e-16 61.2 6.6 1.1e-16 61.2 5.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.6 OWF42228.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OWF42228.1 - 0.0021 18.5 0.1 0.0045 17.5 0.1 1.5 1 0 0 1 1 1 1 PH domain DUF445 PF04286.12 OWF42229.1 - 8.4e-13 48.9 40.1 2.8e-08 34.0 16.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF445) BLM10_mid PF16507.5 OWF42229.1 - 1.8e-08 33.5 6.5 1 7.9 0.0 5.4 1 1 3 6 6 6 4 Proteasome-substrate-size regulator, mid region EcsC PF12787.7 OWF42229.1 - 8e-08 32.3 0.1 1.9 8.1 0.0 5.9 1 1 3 4 4 4 2 EcsC protein family HD_3 PF13023.6 OWF42229.1 - 4.1e-07 30.1 0.1 2.2 8.2 0.1 5.4 1 1 5 6 6 6 2 HD domain LPD14 PF18827.1 OWF42229.1 - 5e-07 30.1 7.0 5.7 7.2 0.1 6.2 1 1 5 7 7 7 2 Large polyvalent protein-associated domain 14 baeRF_family2 PF18844.1 OWF42229.1 - 3.4e-06 27.2 25.9 1.2 9.2 1.2 7.3 1 1 6 8 8 8 5 Bacterial archaeo-eukaryotic release factor family 2 HTH_40 PF14493.6 OWF42229.1 - 7.8e-05 23.1 12.9 22 5.6 0.2 7.4 1 1 6 7 7 7 0 Helix-turn-helix domain DUF223 PF02721.14 OWF42229.1 - 9e-05 22.7 36.5 2.6 8.4 0.7 8.0 1 1 8 9 9 9 4 Domain of unknown function DUF223 Sar8_2 PF03058.14 OWF42229.1 - 0.00081 19.9 18.9 29 5.3 0.1 7.7 1 1 7 8 8 8 0 Sar8.2 family GED PF02212.18 OWF42229.1 - 0.0016 18.5 29.5 9.3 6.5 0.2 8.4 3 1 6 9 9 9 2 Dynamin GTPase effector domain WAC_Acf1_DNA_bd PF10537.9 OWF42229.1 - 0.0017 18.9 17.6 34 5.0 0.2 8.1 2 2 7 9 9 9 0 ATP-utilising chromatin assembly and remodelling N-terminal MgtE_N PF03448.17 OWF42229.1 - 0.026 15.1 6.9 29 5.3 0.2 4.6 2 1 4 6 6 6 0 MgtE intracellular N domain SipA PF09052.10 OWF42229.1 - 0.027 14.1 10.4 5.3 6.6 0.5 4.6 1 1 5 6 6 6 0 SipA N-terminal domain Toxin_8 PF07365.12 OWF42229.1 - 0.027 14.6 26.7 43 4.4 0.1 9.4 3 3 6 12 12 12 0 Alpha conotoxin precursor CelTOS PF18659.1 OWF42229.1 - 0.054 13.9 49.0 6 7.3 1.9 8.4 1 1 7 8 8 8 0 Cell-traversal protein for ookinetes and sporozoites DUF3194 PF11419.8 OWF42229.1 - 0.058 13.7 39.5 46 4.5 0.3 11.3 1 1 6 8 8 8 0 Protein of unknown function (DUF3194) DNTTIP1_dimer PF18192.1 OWF42229.1 - 0.25 11.7 15.8 39 4.7 0.0 8.0 3 2 7 10 10 10 0 DNTTIP1 dimerisation domain DUF3333 PF11812.8 OWF42229.1 - 2.5 8.3 9.0 49 4.1 0.1 4.6 2 1 4 6 6 6 0 Domain of unknown function (DUF3333) HD_4 PF13328.6 OWF42230.1 - 2.1e-21 76.3 0.0 2.7e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 OWF42230.1 - 1.5e-05 25.2 0.2 3.2e-05 24.1 0.2 1.5 1 1 0 1 1 1 1 HD domain Ribosomal_L37e PF01907.19 OWF42230.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e Lipocalin PF00061.23 OWF42231.1 - 0.098 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Kazal_2 PF07648.15 OWF42232.1 - 2.5e-12 46.7 12.0 2.5e-07 30.7 5.8 2.2 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF42232.1 - 2.1e-10 40.4 14.7 1.5e-05 24.9 0.9 2.4 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Mab-21 PF03281.14 OWF42233.1 - 1.6e-33 116.3 3.5 2.4e-33 115.7 3.5 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_7 PF13176.6 OWF42233.1 - 2.8e-05 23.8 0.4 0.19 11.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42233.1 - 0.00016 21.5 0.0 0.24 11.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF42233.1 - 0.00063 20.0 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF42233.1 - 0.0057 16.4 0.0 0.093 12.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF42233.1 - 0.025 14.8 0.0 2.5 8.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat G-patch PF01585.23 OWF42234.1 - 3.1e-09 36.6 2.1 6.3e-09 35.6 2.1 1.5 1 0 0 1 1 1 1 G-patch domain dDENN PF03455.19 OWF42234.1 - 0.17 11.9 1.5 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 dDENN domain GIY-YIG PF01541.24 OWF42235.1 - 3.6e-17 62.4 0.1 1.4e-16 60.6 0.1 1.9 1 1 1 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.8 OWF42235.1 - 1.3e-07 31.7 4.7 2.2e-07 30.9 4.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 OWF42235.1 - 0.0031 17.4 5.9 0.0059 16.5 5.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OWF42235.1 - 0.005 17.1 4.0 0.01 16.1 4.0 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OWF42235.1 - 0.0069 16.5 2.4 0.012 15.8 2.4 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_2 PF13639.6 OWF42235.1 - 0.017 15.5 6.5 0.035 14.4 6.5 1.6 1 0 0 1 1 1 0 Ring finger domain T5orf172 PF10544.9 OWF42235.1 - 0.023 15.2 0.0 0.058 13.9 0.0 1.8 1 0 0 1 1 1 0 T5orf172 domain zf-ribbon_3 PF13248.6 OWF42235.1 - 0.1 12.0 1.4 6.2 6.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain MUG113 PF13455.6 OWF42235.1 - 0.11 13.2 0.1 0.27 11.9 0.1 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Prok-RING_1 PF14446.6 OWF42235.1 - 0.2 11.6 9.4 0.19 11.7 2.8 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OWF42235.1 - 0.33 10.8 4.4 8.1 6.3 0.1 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 OWF42235.1 - 2.1 8.7 7.6 57 4.1 7.9 2.8 1 1 2 3 3 3 0 RING-like domain DZR PF12773.7 OWF42235.1 - 3.6 7.7 7.0 20 5.3 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon NACHT PF05729.12 OWF42236.1 - 1.3e-08 34.9 0.1 3.1e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OWF42236.1 - 0.00038 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain ANAPC4_WD40 PF12894.7 OWF42236.1 - 0.0092 16.3 0.0 7.4 6.9 0.0 3.9 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 OWF42236.1 - 0.033 14.6 0.0 0.092 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 OWF42236.1 - 0.037 14.4 0.1 0.94 9.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 OWF42236.1 - 0.073 13.0 0.2 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea WD40 PF00400.32 OWF42236.1 - 0.13 13.2 1.7 16 6.6 0.2 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Glyco_transf_22 PF03901.17 OWF42237.1 - 4.6e-06 26.1 6.5 0.00016 21.0 0.1 2.5 2 1 1 3 3 3 2 Alg9-like mannosyltransferase family Rad51 PF08423.11 OWF42239.1 - 5.4e-50 170.0 0.0 7.8e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OWF42239.1 - 2.8e-08 33.6 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OWF42239.1 - 2.2e-06 27.2 1.0 2e-05 24.1 1.0 2.2 1 1 0 1 1 1 1 KaiC RecA PF00154.21 OWF42239.1 - 4.5e-05 23.0 0.1 0.0028 17.2 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_33 PF13671.6 OWF42239.1 - 0.039 14.1 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OWF42239.1 - 0.066 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF42239.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OWF42239.1 - 0.15 12.6 0.1 0.39 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain PP2C PF00481.21 OWF42240.1 - 5.3e-66 222.9 0.0 9.8e-66 222.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C CCD PF07860.11 OWF42240.1 - 0.022 14.8 3.9 0.24 11.4 0.2 2.7 2 0 0 2 2 2 0 WisP family C-Terminal Region PP2C_2 PF13672.6 OWF42240.1 - 0.064 12.9 0.0 0.19 11.4 0.0 2.0 1 1 0 1 1 1 0 Protein phosphatase 2C AlphaC_C PF17480.2 OWF42240.1 - 0.17 11.9 1.8 0.28 11.2 0.8 2.0 2 0 0 2 2 2 0 AlphaC C-terminal FANCAA PF15146.6 OWF42241.1 - 0.012 14.7 3.6 14 4.6 0.1 3.8 2 1 1 4 4 4 0 Fanconi anemia-associated Laminin_G_1 PF00054.23 OWF42241.1 - 0.034 14.3 19.5 3.2 8.0 1.7 5.6 1 1 2 3 3 3 0 Laminin G domain NADHdh_A3 PF14987.6 OWF42241.1 - 6.3 7.2 42.9 22 5.4 0.3 9.8 1 1 8 9 9 9 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 zf-B_box PF00643.24 OWF42242.1 - 5.1e-10 39.3 8.0 5.1e-10 39.3 8.0 3.2 2 1 0 2 2 2 1 B-box zinc finger MATH PF00917.26 OWF42242.1 - 1.5e-08 34.8 1.4 5.8e-08 32.9 0.0 2.6 3 0 0 3 3 3 1 MATH domain zf-C3HC4_3 PF13920.6 OWF42242.1 - 0.00046 20.0 16.1 0.00046 20.0 16.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF42242.1 - 0.0061 16.4 17.3 0.0061 16.4 17.3 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF615 PF04751.14 OWF42242.1 - 0.31 11.0 5.1 0.9 9.5 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF615) AAA_28 PF13521.6 OWF42243.1 - 7e-19 68.6 0.0 1.4e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OWF42243.1 - 0.024 14.3 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AsnC_trans_reg2 PF17805.1 OWF42243.1 - 0.12 12.5 0.5 1.2 9.4 0.2 2.5 3 0 0 3 3 3 0 AsnC-like ligand binding domain Astacin PF01400.24 OWF42244.1 - 2.6e-56 190.3 0.1 3.7e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 OWF42244.1 - 7.1e-23 81.1 0.3 1.6e-22 79.9 0.3 1.6 1 0 0 1 1 1 1 CUB domain Reprolysin_5 PF13688.6 OWF42244.1 - 0.018 15.2 1.0 0.044 13.9 0.8 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OWF42244.1 - 0.029 14.0 0.1 0.048 13.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF42244.1 - 0.12 12.3 0.0 0.99 9.2 0.0 2.2 2 0 0 2 2 2 0 Matrixin MFS_1 PF07690.16 OWF42245.1 - 1.2e-39 136.2 30.1 5.8e-27 94.5 17.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF42245.1 - 1.8e-33 116.1 20.8 2.7e-33 115.5 20.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 OWF42245.1 - 5.9e-05 21.8 1.6 5.9e-05 21.8 1.6 3.1 4 1 0 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 OWF42245.1 - 0.0086 15.0 0.0 0.0086 15.0 0.0 2.8 2 1 1 3 3 3 1 MFS_1 like family fn3 PF00041.21 OWF42246.1 - 1.2e-07 31.9 27.8 0.028 14.7 0.1 10.5 12 0 0 12 12 12 3 Fibronectin type III domain TSP_1 PF00090.19 OWF42246.1 - 3.8e-06 27.0 10.0 3.8e-06 27.0 10.0 3.1 2 0 0 2 2 2 1 Thrombospondin type 1 domain ChitinaseA_N PF08329.10 OWF42246.1 - 0.0061 16.2 0.3 11 5.6 0.0 4.0 3 0 0 3 3 3 2 Chitinase A, N-terminal domain DUF2369 PF10179.9 OWF42246.1 - 0.2 12.0 5.4 5.1 7.6 0.2 4.8 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Vitellogenin_N PF01347.22 OWF42247.1 - 1.5e-10 40.1 0.2 3.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Lipoprotein amino terminal region fn3 PF00041.21 OWF42247.1 - 3.4e-06 27.3 5.1 0.0001 22.6 0.3 4.4 3 0 0 3 3 3 1 Fibronectin type III domain Big_9 PF17963.1 OWF42247.1 - 9.7e-05 23.0 0.5 9.7e-05 23.0 0.5 5.6 5 0 0 5 5 5 1 Bacterial Ig domain HEAT_2 PF13646.6 OWF42247.1 - 0.0058 17.0 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 HEAT repeats PAN_1 PF00024.26 OWF42247.1 - 0.011 15.7 0.4 0.05 13.6 0.4 2.1 1 0 0 1 1 1 0 PAN domain HH_signal PF01085.18 OWF42248.1 - 4.3e-13 49.2 0.0 7.2e-09 35.5 0.0 3.0 2 1 1 3 3 3 2 Hedgehog amino-terminal signalling domain Amidase_2 PF01510.25 OWF42249.1 - 1.6e-15 57.6 0.0 1.9e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase UPF0061 PF02696.14 OWF42250.1 - 6.4e-131 437.3 0.0 8e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3467 PF11950.8 OWF42250.1 - 0.15 12.3 0.1 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) BolA PF01722.18 OWF42251.1 - 7.5e-20 71.0 0.0 1.2e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein Halo_GVPC PF05465.13 OWF42251.1 - 0.03 14.6 0.2 0.063 13.5 0.2 1.6 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat IQ PF00612.27 OWF42252.1 - 1.7e-05 24.2 2.2 2.1e-05 23.9 0.3 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Baculo_PEP_C PF04513.12 OWF42252.1 - 0.086 12.9 0.2 0.086 12.9 0.2 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ion_trans PF00520.31 OWF42253.1 - 1.7e-46 158.4 64.9 1.5e-24 86.6 24.1 2.2 2 0 0 2 2 2 2 Ion transport protein DUF1325 PF07039.11 OWF42254.1 - 2e-39 134.7 0.0 4.6e-39 133.5 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain End3 PF12761.7 OWF42254.1 - 0.0063 16.7 2.3 0.0063 16.7 2.3 1.8 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 TUDOR PF00567.24 OWF42254.1 - 0.0084 16.1 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 Tudor domain Tudor_3 PF18115.1 OWF42254.1 - 0.0089 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain ESM4 PF15952.5 OWF42254.1 - 0.014 15.8 2.6 0.022 15.2 2.6 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family ISG65-75 PF11727.8 OWF42254.1 - 0.064 12.5 4.8 0.11 11.7 4.8 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF29 PF01724.16 OWF42254.1 - 0.097 12.9 1.9 0.16 12.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 RPT PF13446.6 OWF42254.1 - 0.11 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein RapH_N PF18801.1 OWF42254.1 - 0.18 11.9 1.6 0.32 11.1 0.3 1.9 1 1 1 2 2 2 0 response regulator aspartate phosphatase H, N terminal RecG_N PF17190.4 OWF42254.1 - 0.41 11.4 4.7 0.47 11.2 2.3 2.0 1 1 1 2 2 2 0 RecG N-terminal helical domain LMBR1 PF04791.16 OWF42254.1 - 1.3 7.9 2.5 1.7 7.4 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TRAM_LAG1_CLN8 PF03798.16 OWF42255.1 - 6.5e-28 97.8 21.4 6.5e-28 97.8 21.4 1.4 2 0 0 2 2 2 1 TLC domain Rad1 PF02144.16 OWF42256.1 - 5.5e-79 265.1 4.3 6.5e-79 264.8 4.3 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 adh_short PF00106.25 OWF42257.1 - 8.8e-28 97.1 0.0 2.8e-27 95.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF42257.1 - 2.8e-19 69.6 0.0 4.6e-19 68.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF42257.1 - 3.7e-07 30.2 0.0 6.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF42257.1 - 0.003 17.1 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OWF42257.1 - 0.0049 16.7 0.1 0.015 15.2 0.1 1.7 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Sacchrp_dh_NADP PF03435.18 OWF42257.1 - 0.0073 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 OWF42257.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Terminase_6C PF17289.2 OWF42257.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Terminase RNaseH-like domain F420_oxidored PF03807.17 OWF42257.1 - 0.15 12.6 0.1 0.47 11.1 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 OWF42258.1 - 6.4e-09 35.2 0.2 7.7e-09 34.9 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF42258.1 - 5.7e-05 22.2 1.6 6.8e-05 21.9 1.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter AKAP7_RIRII_bdg PF10470.9 OWF42259.1 - 0.0035 17.4 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 PKA-RI-RII subunit binding domain of A-kinase anchor protein Pkinase PF00069.25 OWF42260.1 - 2.4e-25 89.4 0.0 3.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42260.1 - 3.2e-17 62.7 0.1 1.6e-16 60.4 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OWF42260.1 - 0.0038 17.2 0.0 1.5 8.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OWF42260.1 - 0.18 11.4 0.1 4.6 6.8 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rep_fac_C PF08542.11 OWF42261.1 - 1.8e-26 92.4 0.0 4.8e-26 91.0 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 OWF42261.1 - 3.9e-13 50.0 0.0 7.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OWF42261.1 - 9.9e-12 44.9 0.0 3.5e-10 39.9 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OWF42261.1 - 1.8e-06 28.5 0.0 0.00014 22.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 OWF42261.1 - 2e-06 27.8 0.0 4.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 OWF42261.1 - 1.4e-05 25.2 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OWF42261.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF42261.1 - 2e-05 24.9 0.2 0.054 13.8 0.1 2.6 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OWF42261.1 - 6.5e-05 22.4 0.0 0.00075 18.9 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 OWF42261.1 - 8.8e-05 22.4 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OWF42261.1 - 0.00016 21.5 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 OWF42261.1 - 0.0003 20.6 0.0 0.00057 19.7 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 OWF42261.1 - 0.00074 19.0 0.1 1.6 8.1 0.1 2.9 3 0 0 3 3 3 2 Bacterial TniB protein AAA_19 PF13245.6 OWF42261.1 - 0.0014 18.9 0.2 0.0064 16.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OWF42261.1 - 0.0015 18.2 0.5 0.027 14.0 0.1 2.5 2 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OWF42261.1 - 0.0027 17.4 0.2 0.0081 15.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 OWF42261.1 - 0.0033 17.2 1.1 0.36 10.6 0.0 2.7 1 1 2 3 3 3 1 DEAD/DEAH box helicase MipZ PF09140.11 OWF42261.1 - 0.004 16.5 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ AAA_5 PF07728.14 OWF42261.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OWF42261.1 - 0.0069 16.9 0.0 0.017 15.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 OWF42261.1 - 0.0073 16.8 0.0 0.019 15.5 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_assoc_2 PF16193.5 OWF42261.1 - 0.0084 16.4 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain ResIII PF04851.15 OWF42261.1 - 0.018 15.0 0.1 8.9 6.3 0.0 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OWF42261.1 - 0.019 14.2 0.5 0.51 9.5 0.5 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 OWF42261.1 - 0.021 13.8 0.0 0.046 12.7 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OWF42261.1 - 0.033 14.6 0.0 0.15 12.4 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 OWF42261.1 - 0.034 14.4 0.2 0.13 12.5 0.1 1.8 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 OWF42261.1 - 0.048 12.8 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OWF42261.1 - 0.051 13.5 0.6 0.21 11.5 0.1 2.1 1 1 0 2 2 2 0 NTPase MCM PF00493.23 OWF42261.1 - 0.063 12.4 0.2 1.2 8.2 0.1 2.3 1 1 1 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 OWF42261.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 OWF42261.1 - 0.15 12.6 0.0 0.2 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF4597 PF15366.6 OWF42261.1 - 0.25 11.1 1.1 27 4.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) CCDC74_C PF14917.6 OWF42262.1 - 8.9e-40 136.0 2.3 8.9e-40 136.0 2.3 3.1 3 0 0 3 3 3 1 Coiled coil protein 74, C terminal CCDC92 PF14916.6 OWF42262.1 - 2.9e-20 71.8 13.4 2.9e-20 71.8 13.4 3.6 4 1 0 4 4 4 1 Coiled-coil domain of unknown function FlxA PF14282.6 OWF42262.1 - 0.0021 18.0 2.4 0.0021 18.0 2.4 3.2 4 0 0 4 4 4 1 FlxA-like protein ExsD PF16806.5 OWF42262.1 - 0.026 14.4 1.0 0.026 14.4 1.0 2.1 2 0 0 2 2 2 0 Antiactivator protein ExsD DUF5053 PF16476.5 OWF42262.1 - 0.11 12.2 1.3 0.29 10.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) PSD1 PF07587.11 OWF42262.1 - 0.21 11.1 7.4 0.33 10.4 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1553) Paralemmin PF03285.15 OWF42262.1 - 0.51 9.9 13.9 0.045 13.3 0.7 2.3 2 0 0 2 2 2 0 Paralemmin WD40_alt PF14077.6 OWF42262.1 - 0.93 9.4 9.4 0.5 10.3 0.4 2.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF383 PF04063.14 OWF42263.1 - 1.4e-56 191.2 6.2 6.2e-56 189.1 0.1 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF383) DUF384 PF04064.13 OWF42263.1 - 3.8e-18 65.1 0.0 1.1e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) UNC45-central PF11701.8 OWF42263.1 - 0.0024 17.8 0.1 1.5 8.7 0.1 2.9 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central DUF3189 PF11385.8 OWF42263.1 - 0.034 14.0 0.1 0.081 12.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3189) CheX PF13690.6 OWF42263.1 - 0.16 12.1 0.0 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX HA2 PF04408.23 OWF42264.1 - 2.3e-24 85.8 0.0 2.3e-24 85.8 0.0 3.0 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OWF42264.1 - 3.7e-18 65.7 0.0 1e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OWF42264.1 - 2.5e-10 40.7 0.2 4.6e-09 36.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF42264.1 - 1.2e-08 34.9 0.2 1.2e-08 34.9 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF42264.1 - 8.6e-06 26.1 0.0 3.4e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OWF42264.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF42264.1 - 0.0015 18.9 1.0 0.0029 18.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OWF42264.1 - 0.0033 16.8 0.1 0.0033 16.8 0.1 1.9 2 0 0 2 2 2 1 KaiC Flavi_DEAD PF07652.14 OWF42264.1 - 0.033 14.2 0.0 0.033 14.2 0.0 2.2 3 0 0 3 3 2 0 Flavivirus DEAD domain AAA_25 PF13481.6 OWF42264.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OWF42264.1 - 0.6 10.6 0.0 0.6 10.6 0.0 3.8 4 1 0 4 4 3 0 AAA domain Vps53_N PF04100.12 OWF42265.1 - 9.9e-155 515.2 1.1 4.1e-154 513.1 0.1 2.1 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 OWF42265.1 - 6e-09 35.6 3.9 1e-08 34.8 1.3 2.5 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 OWF42265.1 - 0.00013 21.9 4.9 0.00024 21.1 0.0 2.8 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 OWF42265.1 - 0.00029 19.8 2.7 0.00042 19.3 0.7 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein NBD94 PF16830.5 OWF42265.1 - 0.00061 20.1 4.1 0.0019 18.5 4.1 1.9 1 0 0 1 1 1 1 Nucleotide-Binding Domain 94 of RH Vps51 PF08700.11 OWF42265.1 - 0.0019 18.2 1.0 0.25 11.4 0.0 3.5 3 0 0 3 3 3 1 Vps51/Vps67 Sec8_exocyst PF04048.14 OWF42265.1 - 0.079 12.9 0.2 0.079 12.9 0.2 2.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 OWF42265.1 - 0.089 12.8 1.3 0.38 10.8 1.3 2.1 1 0 0 1 1 1 0 Laminin Domain II Baculo_PEP_C PF04513.12 OWF42265.1 - 0.4 10.7 4.1 6.3 6.8 3.3 3.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 OWF42265.1 - 1.7 9.1 9.0 0.26 11.7 1.9 3.4 3 1 1 4 4 3 0 Syntaxin-like protein DUF1664 PF07889.12 OWF42265.1 - 4.7 7.3 10.7 2 8.5 2.1 3.9 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Asp_Arg_Hydrox PF05118.15 OWF42266.1 - 7.5e-45 152.6 0.3 1.2e-44 152.0 0.3 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase 7TM_GPCR_Srsx PF10320.9 OWF42266.1 - 0.045 13.1 1.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx DHC_N1 PF08385.12 OWF42267.1 - 1.2e-160 535.8 12.7 1.2e-160 535.8 12.7 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OWF42267.1 - 4.4e-157 522.2 0.0 1.6e-156 520.3 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF42267.1 - 3.1e-136 454.6 8.9 3.1e-136 454.6 8.9 4.9 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OWF42267.1 - 9.1e-104 346.4 0.0 2.8e-103 344.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF42267.1 - 1.7e-85 285.6 2.0 1.7e-85 285.6 2.0 4.1 5 0 0 5 5 4 1 ATP-binding dynein motor region Dynein_C PF18199.1 OWF42267.1 - 2.8e-82 276.4 1.6 7.4e-82 275.0 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 OWF42267.1 - 1.6e-74 249.3 6.2 3.8e-69 231.8 0.0 4.5 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF42267.1 - 1.4e-55 187.5 0.0 4.6e-55 185.9 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF42267.1 - 1.7e-51 175.3 11.5 1.7e-51 175.3 11.5 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF42267.1 - 1.6e-44 150.8 0.0 1.4e-43 147.7 0.1 2.8 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF42267.1 - 2.2e-22 79.5 0.0 8.4e-22 77.6 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF42267.1 - 2.6e-19 69.6 3.1 6.2e-06 26.2 0.0 5.9 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OWF42267.1 - 5.4e-16 58.6 0.1 3.6e-15 56.0 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OWF42267.1 - 7.5e-10 39.2 1.6 0.082 13.2 0.0 6.0 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 OWF42267.1 - 1e-05 26.0 0.1 2.3 8.5 0.0 5.8 5 0 0 5 5 4 1 AAA ATPase domain AAA_18 PF13238.6 OWF42267.1 - 0.0002 21.9 0.1 1.1 9.8 0.0 4.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OWF42267.1 - 0.00032 20.7 1.2 0.0093 15.9 0.1 3.5 4 0 0 4 4 3 1 RsgA GTPase AAA PF00004.29 OWF42267.1 - 0.00037 20.9 7.5 0.59 10.6 0.1 5.9 7 0 0 7 7 5 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 OWF42267.1 - 0.0014 17.6 2.2 0.021 13.7 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain ABC_tran PF00005.27 OWF42267.1 - 0.0019 18.7 0.3 1.1 9.8 0.0 4.8 4 0 0 4 4 4 1 ABC transporter RNA_helicase PF00910.22 OWF42267.1 - 0.016 15.6 0.2 13 6.2 0.0 3.9 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 OWF42267.1 - 0.026 14.2 0.1 4.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 OWF42267.1 - 0.028 14.2 0.2 2.9 7.7 0.0 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OWF42267.1 - 0.062 13.0 2.4 12 5.5 0.1 3.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OWF42267.1 - 0.074 12.4 0.6 0.79 9.0 0.1 2.9 3 0 0 3 3 2 0 FtsK/SpoIIIE family Fungal_TACC PF12709.7 OWF42267.1 - 0.075 13.5 5.3 0.86 10.1 5.3 3.0 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Rad17 PF03215.15 OWF42267.1 - 0.35 10.8 4.0 18 5.2 0.1 3.9 4 0 0 4 4 2 0 Rad17 P-loop domain CENP-Q PF13094.6 OWF42267.1 - 0.43 10.8 7.7 0.58 10.3 1.5 4.2 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2205 PF10224.9 OWF42267.1 - 0.88 9.6 4.0 5.7 7.0 4.0 2.5 1 0 0 1 1 1 0 Short coiled-coil protein AMP-binding PF00501.28 OWF42268.1 - 1e-45 156.2 0.0 1.4e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OWF42268.1 - 1.4e-11 44.1 2.8 3.1e-11 43.0 2.8 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OWF42268.1 - 0.049 14.6 0.1 0.12 13.4 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Lectin_C PF00059.21 OWF42269.1 - 1.9e-10 41.4 0.0 3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain THAP PF05485.12 OWF42270.1 - 3.5e-12 47.1 0.8 3.7e-12 47.0 0.8 1.0 1 0 0 1 1 1 1 THAP domain eIF-3c_N PF05470.12 OWF42271.1 - 2.6e-224 746.0 11.0 5.1e-224 745.0 11.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OWF42271.1 - 1.5e-14 54.4 1.7 1.9e-14 54.0 0.3 2.0 2 0 0 2 2 2 1 PCI domain GRP PF07172.11 OWF42271.1 - 0.38 11.5 14.3 1.4 9.7 14.3 2.0 1 0 0 1 1 1 0 Glycine rich protein family PRESAN PF09687.10 OWF42271.1 - 1.7 9.2 8.4 13 6.3 0.0 4.2 3 1 0 3 3 3 0 Plasmodium RESA N-terminal Cob_adeno_trans PF01923.18 OWF42272.1 - 1.1e-32 113.4 0.0 1.3e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase GHMP_kinases_N PF00288.26 OWF42273.1 - 2.9e-20 72.3 0.3 7.2e-20 71.0 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OWF42273.1 - 1e-11 45.0 0.4 7.3e-11 42.3 0.0 2.5 3 0 0 3 3 3 1 GHMP kinases C terminal Bul1_C PF04426.12 OWF42273.1 - 0.23 10.8 2.3 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 Bul1 C terminus Glyco_hydro81C PF17652.1 OWF42274.1 - 7.5e-54 183.3 2.4 1.2e-53 182.6 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OWF42274.1 - 3.4e-12 46.2 0.8 1.5e-07 30.9 0.1 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain Fibrinogen_C PF00147.18 OWF42275.1 - 2.6e-45 154.9 3.8 4.9e-45 154.0 3.8 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MIF4G_like_2 PF09090.11 OWF42276.1 - 8.4e-05 22.2 3.3 8.4e-05 22.2 3.3 1.9 2 0 0 2 2 2 1 MIF4G like AAA_22 PF13401.6 OWF42276.1 - 0.0022 18.3 4.0 0.0023 18.2 0.0 2.7 3 1 1 4 4 4 1 AAA domain AAA_30 PF13604.6 OWF42276.1 - 0.013 15.2 0.1 0.08 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF42276.1 - 0.02 14.4 0.3 0.18 11.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 OWF42276.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OWF42276.1 - 0.049 13.5 0.2 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 OWF42276.1 - 0.05 14.1 2.7 0.059 13.9 0.0 2.4 3 0 0 3 3 3 0 ABC transporter DUF87 PF01935.17 OWF42276.1 - 0.053 13.6 6.1 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain CpxA_peri PF16527.5 OWF42276.1 - 0.069 13.5 3.1 0.21 12.0 3.1 1.8 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain ATPase PF06745.13 OWF42276.1 - 0.12 11.7 3.3 0.32 10.3 0.0 2.8 2 1 0 2 2 2 0 KaiC AAA_23 PF13476.6 OWF42276.1 - 0.31 11.5 0.0 0.31 11.5 0.0 3.3 2 1 0 2 2 1 0 AAA domain YscO PF07321.12 OWF42276.1 - 0.32 11.0 6.9 0.18 11.8 4.5 1.8 2 0 0 2 2 2 0 Type III secretion protein YscO RRM_1 PF00076.22 OWF42277.1 - 6.5e-16 57.9 0.6 5.3e-07 29.4 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.31 OWF42277.1 - 3.1e-15 56.5 0.2 1.4e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain IBR PF01485.21 OWF42277.1 - 5.5e-14 52.1 21.1 2.8e-08 33.9 9.0 3.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain OB_NTP_bind PF07717.16 OWF42277.1 - 5.2e-09 36.4 0.0 1.7e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OWF42277.1 - 5.7e-09 36.2 0.0 1.6e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Nup35_RRM_2 PF14605.6 OWF42277.1 - 0.022 14.7 0.2 0.067 13.2 0.1 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Helicase_C PF00271.31 OWF42278.1 - 1e-16 61.3 2.5 2.5e-15 56.8 0.0 3.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain IBR PF01485.21 OWF42278.1 - 8.6e-12 45.1 22.5 2e-07 31.1 4.3 4.6 4 0 0 4 4 2 2 IBR domain, a half RING-finger domain RRM_1 PF00076.22 OWF42278.1 - 4.4e-10 39.2 0.2 0.014 15.2 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HA2 PF04408.23 OWF42278.1 - 7.6e-09 35.8 0.0 1.8e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OWF42278.1 - 7e-08 32.7 0.0 2.7e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OWF42278.1 - 1.9e-05 24.5 2.2 4.9e-05 23.2 0.4 2.7 3 0 0 3 3 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF42278.1 - 0.00093 19.5 1.1 0.0069 16.7 0.2 2.8 2 1 0 2 2 2 1 AAA domain MAP65_ASE1 PF03999.12 OWF42278.1 - 0.0022 16.8 1.9 0.0043 15.8 1.9 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) zf_CopZ PF18423.1 OWF42278.1 - 0.0066 16.4 0.1 0.0066 16.4 0.1 3.2 4 0 0 4 4 2 1 Zinc binding domain AAA_30 PF13604.6 OWF42278.1 - 0.012 15.3 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OWF42278.1 - 0.026 14.9 0.5 0.12 12.7 0.1 2.4 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 OWF42278.1 - 0.036 13.4 1.2 1.1 8.6 0.0 3.7 4 0 0 4 4 4 0 KaiC ABC_tran PF00005.27 OWF42278.1 - 0.052 14.1 0.0 0.24 11.9 0.0 2.2 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 OWF42278.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 OWF42278.1 - 0.11 12.4 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 1 0 RsgA GTPase RTX_C PF08339.10 OWF42278.1 - 0.12 12.4 0.3 7.3 6.6 0.0 3.0 3 0 0 3 3 3 0 RTX C-terminal domain AAA_29 PF13555.6 OWF42278.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 OWF42278.1 - 0.24 11.4 1.3 2.5 8.1 0.4 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 OWF42278.1 - 0.26 11.3 1.7 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain DUF16 PF01519.16 OWF42278.1 - 0.57 10.7 4.6 25 5.4 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 GAS PF13851.6 OWF42278.1 - 1.2 8.5 7.9 0.083 12.2 2.4 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Repressor_Mnt PF11423.8 OWF42278.1 - 2.7 7.8 5.0 5 7.0 0.3 3.3 3 0 0 3 3 3 0 Regulatory protein Mnt TSP_1 PF00090.19 OWF42279.1 - 2.3e-10 40.5 6.6 7.2e-10 38.9 6.6 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain FAM60A PF15396.6 OWF42279.1 - 4.1 7.4 6.7 0.56 10.2 0.3 2.3 1 1 1 2 2 2 0 Protein Family FAM60A TMEM132 PF16070.5 OWF42280.1 - 3.1e-93 312.9 0.2 4.3e-93 312.4 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 OWF42280.1 - 2.2e-25 88.2 0.1 5.1e-25 87.1 0.1 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 OWF42280.1 - 1.9e-12 47.2 0.3 7.5e-11 42.0 0.1 2.5 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term T2SS-T3SS_pil_N PF13629.6 OWF42280.1 - 0.06 13.1 2.5 0.066 13.0 0.6 2.1 2 0 0 2 2 2 0 Pilus formation protein N terminal region LSM PF01423.22 OWF42281.1 - 1.8e-14 53.2 0.2 2.3e-14 52.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain zf-C2H2 PF00096.26 OWF42282.1 - 9.8e-16 57.3 43.2 0.00047 20.5 3.2 7.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF42282.1 - 3.1e-14 52.4 43.3 0.0054 17.5 3.6 8.4 7 1 1 8 8 8 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF42282.1 - 7.7e-14 51.4 27.8 0.0024 18.2 0.8 6.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-met PF12874.7 OWF42282.1 - 7.9e-07 29.3 21.7 0.016 15.6 0.4 6.7 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF42282.1 - 0.00011 22.0 0.7 0.00011 22.0 0.7 6.2 6 1 0 6 6 5 2 C2H2-type zinc finger zf_UBZ PF18439.1 OWF42282.1 - 0.0033 17.0 21.9 0.26 10.9 0.0 6.0 6 0 0 6 6 6 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 OWF42282.1 - 0.0054 17.0 29.7 0.015 15.6 0.2 5.9 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OWF42282.1 - 0.028 14.2 20.9 1.6 8.5 0.0 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type SET PF00856.28 OWF42282.1 - 0.056 13.8 4.7 0.12 12.8 3.8 2.1 1 1 0 1 1 1 0 SET domain DUF948 PF06103.11 OWF42282.1 - 0.11 12.7 6.5 0.67 10.3 6.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TF_Zn_Ribbon PF08271.12 OWF42282.1 - 1.5 8.4 17.7 0.85 9.2 0.1 4.8 4 1 1 5 5 5 0 TFIIB zinc-binding Trm112p PF03966.16 OWF42282.1 - 1.8 9.2 8.0 1.7 9.3 0.8 3.7 3 0 0 3 3 2 0 Trm112p-like protein zf-C2H2_8 PF15909.5 OWF42282.1 - 1.9 8.8 14.8 1.6 9.0 0.6 3.5 1 1 0 3 3 3 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 OWF42282.1 - 3.2 8.1 27.4 0.091 13.1 5.0 4.8 2 2 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 OWF42282.1 - 5 6.8 10.1 8.2 6.1 1.2 4.2 3 1 1 4 4 4 0 MYST family zinc finger domain zf-C2H2 PF00096.26 OWF42283.1 - 1.4e-16 59.9 47.7 3.9e-05 23.9 3.1 7.8 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF42283.1 - 3.6e-14 52.3 46.8 0.005 17.6 6.3 8.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF42283.1 - 3.2e-11 43.1 35.3 0.0091 16.4 0.9 6.4 6 0 0 6 6 5 5 Zinc-finger double domain zf-met PF12874.7 OWF42283.1 - 6.3e-05 23.2 25.3 0.013 15.9 0.4 6.9 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF42283.1 - 0.0056 16.6 0.4 0.0056 16.6 0.4 6.6 7 0 0 7 7 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF42283.1 - 0.013 15.8 0.2 0.013 15.8 0.2 6.6 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OWF42283.1 - 0.022 14.5 21.0 1.1 9.0 1.3 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type zf_UBZ PF18439.1 OWF42283.1 - 0.073 12.7 25.6 0.15 11.7 0.0 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Trm112p PF03966.16 OWF42283.1 - 0.16 12.5 8.0 0.42 11.2 0.3 4.0 3 0 0 3 3 3 0 Trm112p-like protein Peptidase_S26 PF10502.9 OWF42283.1 - 0.18 11.6 2.2 0.47 10.2 1.2 2.1 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 SET PF00856.28 OWF42283.1 - 0.23 11.9 4.8 0.93 9.9 4.8 2.2 1 1 0 1 1 1 0 SET domain zf-C2H2_8 PF15909.5 OWF42283.1 - 0.3 11.4 15.6 0.4 11.0 0.6 3.5 1 1 0 2 2 2 0 C2H2-type zinc ribbon PhageMin_Tail PF10145.9 OWF42283.1 - 0.34 10.8 8.9 0.042 13.7 4.6 1.6 2 0 0 2 2 2 0 Phage-related minor tail protein MCPsignal PF00015.21 OWF42283.1 - 0.45 10.3 14.8 0.044 13.6 9.6 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1993 PF09351.10 OWF42283.1 - 2.1 8.4 6.4 6.8 6.8 6.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF948 PF06103.11 OWF42283.1 - 2.4 8.5 8.8 16 5.8 8.8 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Metallophos PF00149.28 OWF42284.1 - 1.5e-39 136.7 0.1 2e-39 136.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OWF42284.1 - 0.0016 18.8 2.3 0.0017 18.8 0.8 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OWF42284.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Band_7 PF01145.25 OWF42285.1 - 1.7e-21 77.0 0.0 1.7e-21 77.0 0.0 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 OWF42285.1 - 3.8e-07 30.3 7.8 3.8e-07 30.3 7.8 3.1 2 2 1 3 3 3 1 Flotillin Band_7_1 PF13421.6 OWF42285.1 - 0.03 14.0 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family P21-Arc PF04062.14 OWF42286.1 - 8.5e-72 240.8 0.0 9.5e-72 240.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit P21-Arc PF04062.14 OWF42287.1 - 1.7e-78 262.6 0.5 2e-78 262.4 0.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit LIX1 PF14954.6 OWF42287.1 - 0.023 14.0 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Limb expression 1 ATP_bind_1 PF03029.17 OWF42288.1 - 6e-89 298.0 0.1 6.8e-89 297.8 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OWF42288.1 - 0.00033 21.2 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 OWF42288.1 - 0.0022 17.8 0.0 0.017 14.9 0.0 2.3 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_17 PF13207.6 OWF42288.1 - 0.0032 17.9 0.0 0.039 14.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain Bacillus_HBL PF05791.11 OWF42288.1 - 0.0082 16.0 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) AAA_22 PF13401.6 OWF42288.1 - 0.012 15.9 0.0 0.061 13.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OWF42288.1 - 0.014 15.5 0.0 0.044 13.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 OWF42288.1 - 0.028 14.4 0.0 0.58 10.1 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OWF42288.1 - 0.04 14.1 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF42288.1 - 0.095 13.1 0.0 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 OWF42288.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OWF42288.1 - 0.11 12.5 0.0 0.34 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OWF42288.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OWF42288.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 OWF42288.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 OWF42288.1 - 0.16 12.1 0.0 0.41 10.7 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Porin_4 PF13609.6 OWF42289.1 - 1.4e-13 51.3 2.6 2.3e-06 27.6 1.0 2.8 1 1 1 2 2 2 2 Gram-negative porin Tim17 PF02466.19 OWF42290.1 - 6.9e-26 90.8 8.2 8.8e-26 90.5 8.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 OWF42290.1 - 5.8 7.4 16.9 0.97 9.8 3.4 2.8 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Rogdi_lz PF10259.9 OWF42291.1 - 1.5e-24 86.9 0.2 5e-24 85.2 0.2 1.7 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein SCAPER_N PF16501.5 OWF42291.1 - 0.16 12.0 4.2 7.5 6.6 0.0 3.0 3 0 0 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum Diphthamide_syn PF01866.17 OWF42292.1 - 1e-119 399.5 0.0 1.2e-119 399.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Glyco_hydro_10 PF00331.20 OWF42293.1 - 8.2e-46 156.6 2.9 1.3e-45 155.9 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 OWF42293.1 - 1.1e-14 54.9 0.0 2.8e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 OWF42293.1 - 7.2e-05 22.5 0.7 0.00025 20.7 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase catalytic core Glyco_hydro_10 PF00331.20 OWF42294.1 - 7.9e-45 153.4 3.1 1.2e-44 152.8 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 OWF42294.1 - 2.4e-14 53.8 0.0 1e-13 51.7 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 OWF42294.1 - 0.00055 19.6 0.1 0.0016 18.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core AAT PF03417.16 OWF42295.1 - 1.2e-29 103.6 0.0 1.9e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase zf-RING_UBOX PF13445.6 OWF42296.1 - 9e-07 28.8 8.6 9e-07 28.8 8.6 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF42296.1 - 1.4e-06 28.1 11.8 1.4e-06 28.1 11.8 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF42296.1 - 1.5e-06 28.3 22.0 0.0002 21.4 6.5 3.9 4 0 0 4 4 4 2 B-box zinc finger zf-RING_2 PF13639.6 OWF42296.1 - 1.6e-05 25.1 10.6 1.6e-05 25.1 10.6 3.4 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 OWF42296.1 - 8.2e-05 22.5 9.4 8.2e-05 22.5 9.4 3.2 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF42296.1 - 0.0014 18.7 11.6 0.0014 18.7 11.6 3.9 3 2 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF42296.1 - 0.0024 17.7 11.6 0.0024 17.7 11.6 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF2180 PF09947.9 OWF42296.1 - 0.026 14.5 3.8 0.026 14.5 3.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Prok-RING_4 PF14447.6 OWF42296.1 - 0.029 14.2 9.0 0.029 14.2 9.0 3.7 3 2 0 3 3 3 0 Prokaryotic RING finger family 4 DUF5447 PF17525.2 OWF42296.1 - 4.5 7.8 16.8 1.8 9.1 3.2 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5447) Vitellogenin_N PF01347.22 OWF42297.1 - 0.042 12.3 0.0 0.049 12.0 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Rab_bind PF16704.5 OWF42297.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Rab binding domain VWD PF00094.25 OWF42298.1 - 7.6e-18 65.3 0.5 7.6e-18 65.3 0.5 2.9 3 0 0 3 3 3 1 von Willebrand factor type D domain Apolipoprotein PF01442.18 OWF42298.1 - 0.031 14.2 0.1 0.65 9.8 0.0 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Syntaxin_2 PF14523.6 OWF42298.1 - 0.049 14.0 0.1 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Syntaxin-like protein CHASE5 PF17149.4 OWF42298.1 - 0.05 13.5 0.1 0.19 11.6 0.1 2.1 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins TSC22 PF01166.18 OWF42298.1 - 0.39 11.1 2.5 5.9 7.3 1.0 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Ldl_recept_a PF00057.18 OWF42299.1 - 1.8e-05 24.9 1.0 2.9e-05 24.2 1.0 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Apolipoprotein PF01442.18 OWF42300.1 - 1.7e-34 119.3 0.0 3e-07 30.5 0.0 5.0 1 1 4 5 5 5 5 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OWF42300.1 - 1.3e-05 25.7 8.6 84 3.9 0.1 7.6 1 1 6 8 8 8 0 Bacterial protein of unknown function (DUF883) TMEM214 PF10151.9 OWF42300.1 - 0.0026 16.3 0.0 23 3.3 0.0 4.6 1 1 2 3 3 3 3 TMEM214, C-terminal, caspase 4 activator Sterile PF03015.19 OWF42300.1 - 5.5 7.3 83.0 1.1e+02 3.1 0.4 19.0 1 1 38 39 39 39 0 Male sterility protein Apolipoprotein PF01442.18 OWF42301.1 - 8.2e-11 42.1 0.0 7.2e-09 35.8 0.0 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF2316 PF10078.9 OWF42301.1 - 0.0042 17.3 0.8 19 5.6 0.4 5.0 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2316) Sterile PF03015.19 OWF42301.1 - 0.0091 16.2 27.6 3.9 7.8 0.2 7.9 3 1 6 9 9 9 2 Male sterility protein Mrpl_C PF18502.1 OWF42301.1 - 0.022 15.0 0.8 66 3.8 0.0 4.9 1 1 3 5 5 5 0 54S ribosomal protein L8 C-terminal domain DUF1451 PF07295.11 OWF42301.1 - 0.033 14.2 0.1 1.3 9.0 0.1 2.6 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF883 PF05957.13 OWF42301.1 - 0.088 13.4 0.3 4.2 8.0 0.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1877 PF08974.10 OWF42301.1 - 0.51 10.4 7.8 6.2 6.9 0.8 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF1877) Cyt-b5 PF00173.28 OWF42301.1 - 0.57 10.4 13.5 22 5.3 1.3 5.6 1 1 2 4 4 4 0 Cytochrome b5-like Heme/Steroid binding domain PadR PF03551.14 OWF42301.1 - 0.72 9.9 25.4 0.73 9.8 0.9 5.2 1 1 5 6 6 6 0 Transcriptional regulator PadR-like family ADPrib_exo_Tox PF03496.14 OWF42301.1 - 1.7 7.9 12.9 12 5.2 0.7 4.3 1 1 3 4 4 4 0 ADP-ribosyltransferase exoenzyme Amino_oxidase PF01593.24 OWF42302.1 - 0.036 13.3 0.0 0.036 13.3 0.0 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Tfb2 PF03849.14 OWF42302.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb2 Sulfotransfer_1 PF00685.27 OWF42304.1 - 0.00053 19.6 0.1 0.00057 19.4 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Glyco_transf_10 PF00852.19 OWF42305.1 - 1e-42 145.8 4.7 1.7e-42 145.1 4.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF42305.1 - 1.6e-18 67.2 1.4 2.1e-17 63.6 0.0 2.7 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal zf_PR_Knuckle PF18445.1 OWF42305.1 - 0.09 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif Sulfotransfer_1 PF00685.27 OWF42306.1 - 1.1e-11 44.7 0.3 2.4e-11 43.6 0.3 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF42306.1 - 1.7e-11 44.9 0.0 1.3e-10 42.1 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Glyco_transf_24 PF18404.1 OWF42306.1 - 0.017 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 EI24 PF07264.11 OWF42308.1 - 9.7e-18 65.0 20.3 9.7e-18 65.0 20.3 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Tim54 PF11711.8 OWF42308.1 - 0.043 12.6 0.2 0.064 12.0 0.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_S25 PF03297.15 OWF42309.1 - 7.7e-44 148.0 1.9 1e-43 147.6 1.9 1.2 1 0 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 OWF42309.1 - 0.0079 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Prefoldin_2 PF01920.20 OWF42310.1 - 5.4e-26 90.6 6.4 7.8e-26 90.1 6.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit BAR_3 PF16746.5 OWF42310.1 - 0.0029 17.3 1.7 0.004 16.9 1.7 1.1 1 0 0 1 1 1 1 BAR domain of APPL family DivIVA PF05103.13 OWF42310.1 - 0.012 15.7 4.7 0.24 11.5 0.1 2.4 1 1 0 2 2 2 0 DivIVA protein EFhand_Ca_insen PF08726.10 OWF42310.1 - 0.06 13.4 0.4 0.12 12.5 0.4 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF2004 PF09406.10 OWF42310.1 - 0.078 13.3 0.9 0.65 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) OmpH PF03938.14 OWF42310.1 - 0.1 12.9 5.3 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PHM7_cyt PF14703.6 OWF42310.1 - 0.47 10.7 6.2 3.2 7.9 0.8 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4061 PF13270.6 OWF42310.1 - 0.57 10.5 5.0 0.33 11.3 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF641 PF04859.12 OWF42310.1 - 5.8 7.3 7.8 7 7.0 1.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fibritin_C PF07921.12 OWF42311.1 - 0.12 12.5 0.5 0.32 11.2 0.5 1.8 1 0 0 1 1 1 0 Fibritin C-terminal region Homeodomain PF00046.29 OWF42312.1 - 2.3e-21 75.4 0.7 3.7e-21 74.7 0.7 1.4 1 0 0 1 1 1 1 Homeodomain CspB_prodomain PF18425.1 OWF42313.1 - 0.12 12.4 6.9 4 7.5 0.4 2.9 1 1 1 2 2 2 0 Csp protease B prodomain DUF3697 PF12478.8 OWF42313.1 - 0.5 10.5 2.6 64 3.8 0.2 4.0 2 2 3 5 5 5 0 Ubiquitin-associated protein 2 Cu2_monooxygen PF01082.20 OWF42313.1 - 0.64 10.3 3.1 9.8 6.4 0.1 2.8 2 2 1 3 3 3 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain D5_N PF08706.11 OWF42314.1 - 0.0091 16.3 0.2 2.9 8.1 0.0 2.5 1 1 1 2 2 2 2 D5 N terminal like AsmA_2 PF13502.6 OWF42314.1 - 0.019 14.5 1.8 1.7 8.1 0.2 2.6 2 1 0 2 2 2 0 AsmA-like C-terminal region DUF3697 PF12478.8 OWF42314.1 - 0.081 13.0 4.7 19 5.5 0.0 4.5 3 2 2 5 5 5 0 Ubiquitin-associated protein 2 Mab-21 PF03281.14 OWF42315.1 - 3.4e-30 105.4 0.0 5.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF42315.1 - 0.039 14.2 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42315.1 - 0.059 13.5 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Mab-21 PF03281.14 OWF42316.1 - 8.1e-31 107.4 0.2 1.2e-30 106.8 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF42316.1 - 0.0019 18.5 0.2 0.062 13.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42316.1 - 0.057 13.6 0.0 0.76 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Chlor_dismutase PF06778.12 OWF42317.1 - 0.038 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorite dismutase Mab-21 PF03281.14 OWF42318.1 - 1.1e-27 97.1 0.1 1.7e-27 96.5 0.1 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF42318.1 - 0.0026 18.0 0.0 0.071 13.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42318.1 - 0.052 13.7 0.0 1.7 9.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Mab-21 PF03281.14 OWF42319.1 - 2.3e-26 92.8 0.1 3.5e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Mab-21 protein PGG PF13962.6 OWF42319.1 - 0.00081 19.2 0.3 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function VWA_2 PF13519.6 OWF42320.1 - 2.3e-15 57.1 1.6 5.6e-15 55.9 0.1 2.6 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 OWF42320.1 - 3e-15 56.9 0.3 3e-15 56.9 0.3 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF42320.1 - 2e-05 24.6 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain HisG_C PF08029.11 OWF42320.1 - 0.11 12.6 0.0 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 HisG, C-terminal domain TMEM192 PF14802.6 OWF42321.1 - 3.2e-24 85.3 5.2 4.2e-24 85.0 5.2 1.1 1 0 0 1 1 1 1 TMEM192 family DUF872 PF05915.12 OWF42321.1 - 0.068 13.3 0.4 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) ABC2_membrane_2 PF12679.7 OWF42321.1 - 0.099 11.9 1.8 0.14 11.4 1.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Fumarate_red_D PF02313.17 OWF42321.1 - 0.15 12.2 6.1 0.077 13.1 0.7 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit D TIMP PF00965.17 OWF42323.1 - 5.2e-25 88.3 10.0 4e-24 85.4 10.0 1.9 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF42323.1 - 1.9e-05 24.4 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.17 OWF42324.1 - 2.4e-24 86.1 10.1 6.7e-24 84.7 10.1 1.8 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF42324.1 - 1.3e-08 34.6 3.8 0.001 18.9 0.0 2.8 3 1 0 3 3 3 2 UNC-6/NTR/C345C module TIMP PF00965.17 OWF42325.1 - 1.8e-27 96.3 4.2 4.3e-27 95.1 4.2 1.6 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase TIMP PF00965.17 OWF42326.1 - 1.2e-21 77.4 9.3 1.4e-21 77.1 9.3 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF42326.1 - 0.00066 19.4 0.1 0.0071 16.1 0.1 2.3 1 1 1 2 2 2 1 UNC-6/NTR/C345C module TMF_TATA_bd PF12325.8 OWF42327.1 - 0.27 11.5 26.8 0.55 10.5 6.2 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 OWF42327.1 - 0.44 10.6 31.2 0.16 12.1 9.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3053 PF11254.8 OWF42327.1 - 0.45 10.1 12.5 0.045 13.3 2.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3053) MMPL PF03176.15 OWF42327.1 - 0.49 9.3 2.3 0.72 8.7 2.3 1.2 1 0 0 1 1 1 0 MMPL family DUF4407 PF14362.6 OWF42327.1 - 0.5 9.7 23.7 9.8 5.4 23.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 OWF42327.1 - 0.81 8.3 24.0 1.6 7.2 23.8 1.4 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.11 OWF42327.1 - 1.3 7.9 33.9 0.87 8.4 16.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein V-SNARE PF05008.15 OWF42327.1 - 1.3 9.5 29.4 0.83 10.1 6.0 4.4 3 2 2 5 5 5 0 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.12 OWF42327.1 - 2.7 8.1 22.2 0.21 11.7 2.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YtxH PF12732.7 OWF42327.1 - 3.2 8.4 18.1 62 4.2 0.7 3.5 1 1 1 2 2 2 0 YtxH-like protein Macoilin PF09726.9 OWF42327.1 - 5.1 5.5 27.2 5.7 5.4 27.2 1.1 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 OWF42327.1 - 7.5 4.4 16.8 6.2 4.6 4.0 2.0 1 1 1 2 2 2 0 Prominin DUF16 PF01519.16 OWF42327.1 - 8.9 6.9 27.4 1.9 9.0 5.0 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 WAP PF00095.21 OWF42328.1 - 5.5e-09 36.3 30.3 7.7e-06 26.2 9.3 2.1 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' MFS_5 PF05631.14 OWF42329.1 - 8.5e-142 472.2 18.4 7.8e-141 469.1 18.4 1.9 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OWF42329.1 - 1.6e-19 70.0 24.2 1.6e-19 70.0 24.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Dynamin_M PF01031.20 OWF42330.1 - 2.6e-99 332.0 0.8 6.4e-99 330.8 0.0 2.1 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 OWF42330.1 - 2.4e-52 177.4 0.1 2.4e-52 177.4 0.1 2.5 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 OWF42330.1 - 3e-31 107.4 2.5 3e-31 107.4 2.5 2.2 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OWF42330.1 - 8.8e-05 22.6 0.1 0.00036 20.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OWF42330.1 - 0.0021 18.5 0.3 0.015 15.7 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain NUC202 PF08166.12 OWF42330.1 - 0.038 14.1 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 NUC202 domain Roc PF08477.13 OWF42330.1 - 0.091 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase zf-CpG_bind_C PF12269.8 OWF42331.1 - 3.3e-103 344.5 11.2 3.3e-103 344.5 11.2 2.2 2 1 0 2 2 2 1 CpG binding protein zinc finger C terminal domain zf-CXXC PF02008.20 OWF42331.1 - 1.1e-15 57.4 23.4 1.1e-15 57.4 23.4 4.4 5 0 0 5 5 5 1 CXXC zinc finger domain PHD PF00628.29 OWF42331.1 - 8.7e-10 38.3 10.9 8.7e-10 38.3 10.9 4.2 4 1 0 4 4 4 1 PHD-finger PHD_3 PF13922.6 OWF42331.1 - 0.02 15.2 3.0 0.035 14.5 0.7 2.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx MRP-L46 PF11788.8 OWF42332.1 - 3.8e-07 30.9 0.6 9.9e-07 29.5 0.1 1.9 1 1 1 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 OWF42332.1 - 2e-06 27.8 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RPAP3_C PF13877.6 OWF42333.1 - 3.5e-19 69.1 0.3 1e-18 67.7 0.3 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 OWF42333.1 - 1.2e-15 56.6 5.1 0.0003 20.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42333.1 - 2.8e-11 42.6 6.5 0.00094 19.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF42333.1 - 2.7e-10 39.6 1.5 0.00062 19.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF42333.1 - 3.6e-06 26.5 2.4 0.00044 19.9 0.1 3.0 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 OWF42333.1 - 7.2e-05 23.2 5.6 0.0047 17.4 0.8 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF42333.1 - 9.2e-05 23.0 2.8 0.0078 16.8 0.8 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF42333.1 - 0.0022 17.9 0.7 0.24 11.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF42333.1 - 0.0026 17.8 0.5 0.0026 17.8 0.5 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OWF42333.1 - 0.0068 17.0 3.6 0.057 14.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF42333.1 - 0.02 15.0 0.6 0.32 11.2 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF42333.1 - 0.17 12.8 2.3 4.9 8.2 0.0 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat Imm-NTF2 PF15655.6 OWF42333.1 - 0.22 11.8 9.5 0.88 9.9 0.3 3.3 2 1 0 3 3 3 0 NTF2 fold immunity protein TPR_12 PF13424.6 OWF42333.1 - 0.5 10.7 3.7 8.2 6.8 0.8 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat ABC_trans_CmpB PF06541.11 OWF42334.1 - 2.9e-08 34.1 8.4 4.1e-08 33.6 8.4 1.3 1 0 0 1 1 1 1 Putative ABC-transporter type IV Babuvirus_MP PF07234.11 OWF42334.1 - 3.4 7.9 5.0 0.68 10.1 1.5 1.6 2 0 0 2 2 2 0 Movement and RNA silencing protein HlyIII PF03006.20 OWF42335.1 - 8.1e-71 238.3 20.2 1e-70 238.0 20.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.6 OWF42336.1 - 5.8e-23 79.0 20.2 0.0022 17.9 0.0 8.6 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 OWF42336.1 - 3.9e-09 35.8 0.1 7.1 7.6 2.2 7.4 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 OWF42336.1 - 0.003 17.9 21.2 0.29 11.6 0.9 5.5 2 1 6 8 8 8 5 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 OWF42336.1 - 0.01 16.3 0.1 0.056 13.9 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 OWF42336.1 - 0.021 14.3 0.0 0.062 12.9 0.0 1.9 1 0 0 1 1 1 0 EF hand LRR_8 PF13855.6 OWF42336.1 - 0.071 12.9 12.9 2 8.2 1.5 5.1 2 1 3 5 5 5 0 Leucine rich repeat EF-hand_6 PF13405.6 OWF42336.1 - 0.15 12.1 0.0 0.58 10.2 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain AlaDh_PNT_C PF01262.21 OWF42336.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sulfate_transp PF00916.20 OWF42337.1 - 1.5e-113 379.4 15.6 2.1e-113 378.9 15.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OWF42337.1 - 1.9e-27 95.2 0.2 4.8e-27 93.9 0.2 1.7 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OWF42337.1 - 0.0039 17.5 0.0 0.0086 16.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain NDUF_B12 PF08122.12 OWF42337.1 - 0.12 12.5 5.2 2.3 8.3 0.3 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Nuc_deoxyri_tr3 PF11071.8 OWF42338.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Neur_chan_memb PF02932.16 OWF42339.1 - 0.046 13.8 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Adeno_E3B PF03376.14 OWF42339.1 - 0.048 13.9 1.2 9.1 6.6 0.3 2.3 2 0 0 2 2 2 0 Adenovirus E3B protein LapA_dom PF06305.11 OWF42339.1 - 0.056 13.3 2.0 0.067 13.0 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_S26e PF01283.19 OWF42339.1 - 0.087 13.3 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S26e DUF4059 PF13268.6 OWF42339.1 - 0.12 12.7 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) FeoB_associated PF12669.7 OWF42339.1 - 0.13 12.7 3.1 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein CbiM PF01891.16 OWF42339.1 - 0.14 12.0 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region DUF4381 PF14316.6 OWF42339.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Polysacc_lyase PF14099.6 OWF42340.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 1 1 2 2 2 0 Polysaccharide lyase Internalin_N PF12354.8 OWF42341.1 - 0.091 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Cu-oxidase_3 PF07732.15 OWF42342.1 - 2.1e-41 140.7 0.1 2.3e-38 130.8 0.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF42342.1 - 8.1e-34 116.3 1.3 6.4e-29 100.4 0.1 3.9 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF42342.1 - 5.5e-28 98.1 0.0 7.5e-25 87.9 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase DUF4051 PF13260.6 OWF42342.1 - 0.17 11.6 1.6 1.7 8.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) MIP PF00230.20 OWF42344.1 - 6e-06 26.1 5.6 3.1e-05 23.8 4.7 2.0 1 1 1 2 2 2 2 Major intrinsic protein GMC_oxred_N PF00732.19 OWF42345.1 - 6.8e-73 245.6 0.0 1.2e-72 244.8 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF42345.1 - 4.5e-32 111.5 0.0 7.1e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OWF42345.1 - 3.3e-06 26.6 0.1 0.0064 15.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF42345.1 - 6.6e-06 25.4 0.0 0.011 14.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OWF42345.1 - 0.00012 22.2 0.4 0.00056 20.1 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF42345.1 - 0.00019 21.2 0.0 0.0062 16.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF42345.1 - 0.00044 19.4 0.0 0.00065 18.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OWF42345.1 - 0.0017 17.7 0.0 0.0057 15.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OWF42345.1 - 0.088 13.1 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 OWF42345.1 - 0.19 12.3 0.0 5.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 OWF42346.1 - 1.1e-12 48.4 0.0 2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF42346.1 - 8.4e-12 45.6 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF42346.1 - 3.9e-09 36.6 0.0 4.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42346.1 - 5e-09 36.1 0.0 6.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF42346.1 - 6.3e-09 35.6 0.0 8.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OWF42346.1 - 2e-06 28.5 0.0 3.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 OWF42346.1 - 1.5e-05 24.6 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 OWF42346.1 - 0.00083 19.1 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OWF42346.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OWF42346.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 OWF42346.1 - 0.038 13.4 0.0 2.4 7.5 0.0 2.4 2 1 0 2 2 2 0 Tellurite resistance protein TehB N2227 PF07942.12 OWF42346.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein GidB PF02527.15 OWF42346.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 OWF42347.1 - 1.4e-12 48.1 0.0 2.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF42347.1 - 5.2e-12 46.3 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42347.1 - 1.6e-09 37.7 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF42347.1 - 1.9e-09 37.6 0.0 2.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF42347.1 - 1.8e-06 28.6 0.0 3.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF42347.1 - 5.4e-06 26.1 0.0 6.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OWF42347.1 - 0.00011 21.6 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 OWF42347.1 - 0.0002 21.0 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 OWF42347.1 - 0.00042 20.1 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OWF42347.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) ASC PF00858.24 OWF42348.1 - 2.6e-89 300.2 10.2 2.6e-71 240.9 6.0 2.4 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel EAF PF09816.9 OWF42349.1 - 4.4e-21 75.2 0.0 8.4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Methyltransf_12 PF08242.12 OWF42350.1 - 8.8e-17 61.7 0.0 4.2e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF42350.1 - 3.4e-15 56.5 0.0 6.2e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF42350.1 - 1.7e-12 47.5 0.0 3.7e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF42350.1 - 1.6e-11 44.7 0.0 3.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42350.1 - 6.7e-09 35.7 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF42350.1 - 0.00077 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 OWF42350.1 - 0.0056 15.3 0.0 0.021 13.4 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 OWF42350.1 - 0.013 14.9 0.0 0.08 12.4 0.0 2.1 1 1 0 1 1 1 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.17 OWF42350.1 - 0.066 12.4 0.0 0.19 10.9 0.0 1.7 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family NodS PF05401.11 OWF42350.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) RBB1NT PF08169.11 OWF42350.1 - 0.63 10.2 2.5 0.95 9.7 0.7 2.0 2 0 0 2 2 2 0 RBB1NT (NUC162) domain Activin_recp PF01064.23 OWF42351.1 - 0.00031 21.8 10.8 0.00031 21.8 10.8 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain EphA2_TM PF14575.6 OWF42351.1 - 0.025 15.5 0.0 0.061 14.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF42351.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Pkinase_Tyr PF07714.17 OWF42352.1 - 2.4e-65 220.4 0.0 3.6e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF42352.1 - 2.7e-53 181.0 0.0 5.2e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 OWF42352.1 - 4e-11 43.2 0.3 8.1e-11 42.2 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF42352.1 - 4.3e-11 42.7 0.2 8.3e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF42352.1 - 0.0041 17.1 0.2 0.01 15.8 0.2 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sipho_Gp157 PF05565.11 OWF42352.1 - 0.012 15.7 4.1 0.021 14.9 4.1 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF3552 PF12072.8 OWF42352.1 - 0.014 14.8 7.4 0.024 14.1 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SAM_4 PF18017.1 OWF42352.1 - 0.09 12.8 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pox_A31 PF05771.11 OWF42352.1 - 0.097 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A31 protein GNAT_acetyltran PF12746.7 OWF42352.1 - 0.14 11.7 1.7 0.26 10.8 1.7 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase NHL PF01436.21 OWF42353.1 - 3.4e-55 181.4 16.5 7.6e-09 35.2 0.1 6.7 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 OWF42353.1 - 2.4e-13 50.0 11.3 3.5e-07 29.7 0.1 3.8 2 1 2 4 4 4 4 6-bladed beta-propeller zf-C3HC4 PF00097.25 OWF42353.1 - 7.8e-09 35.3 9.8 7.8e-09 35.3 9.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF42353.1 - 1.8e-08 34.3 0.3 0.1 12.2 0.0 3.5 3 0 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 OWF42353.1 - 5.3e-08 32.8 8.5 5.3e-08 32.8 8.5 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF42353.1 - 2.6e-06 27.2 8.0 2.6e-06 27.2 8.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF42353.1 - 3.7e-06 26.7 10.2 3.7e-06 26.7 10.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF42353.1 - 1e-05 25.7 9.3 1e-05 25.7 9.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF42353.1 - 5.8e-05 23.0 8.4 5.8e-05 23.0 8.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF42353.1 - 0.0017 18.4 10.2 0.0017 18.4 10.2 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OWF42353.1 - 0.0062 16.3 2.4 0.0062 16.3 2.4 2.8 3 0 0 3 3 3 1 RING-like zinc finger Phytase-like PF13449.6 OWF42353.1 - 0.018 15.0 0.0 8.5 6.2 0.0 3.8 3 2 0 3 3 3 0 Esterase-like activity of phytase SBBP PF06739.11 OWF42353.1 - 0.037 14.0 0.0 19 5.4 0.0 3.6 3 0 0 3 3 3 0 Beta-propeller repeat HTH_Crp_2 PF13545.6 OWF42353.1 - 0.064 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF3215 PF11503.8 OWF42353.1 - 0.076 12.9 0.6 14 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3215) DUF3439 PF11921.8 OWF42353.1 - 0.14 12.1 5.0 0.32 11.0 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-B_box PF00643.24 OWF42353.1 - 3.5 7.9 17.1 0.054 13.6 7.8 2.7 3 0 0 3 3 2 0 B-box zinc finger Prok-RING_4 PF14447.6 OWF42353.1 - 5 7.1 26.4 0.21 11.5 8.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 APG9 PF04109.16 OWF42354.1 - 2.5e-178 594.0 19.1 3.1e-178 593.7 19.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Pkinase PF00069.25 OWF42356.1 - 8e-58 195.9 0.0 1.8e-57 194.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42356.1 - 1.4e-37 129.4 0.0 2.4e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 OWF42356.1 - 3.7e-08 33.1 3.5 0.00083 19.3 0.1 5.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 OWF42356.1 - 6e-07 28.6 0.0 1.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OWF42356.1 - 8.7e-06 25.8 0.0 4.4e-05 23.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF42356.1 - 3.1e-05 23.1 0.2 7.2e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OWF42356.1 - 0.00018 21.2 0.1 0.00045 19.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OWF42356.1 - 0.0056 16.0 0.0 0.015 14.6 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Atx10homo_assoc PF09759.9 OWF42356.1 - 0.013 15.6 0.2 0.095 12.7 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Pox_ser-thr_kin PF05445.11 OWF42356.1 - 0.034 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 OWF42356.1 - 0.54 9.8 2.9 0.57 9.7 0.1 2.4 3 0 0 3 3 3 0 Choline/ethanolamine kinase Carn_acyltransf PF00755.20 OWF42357.1 - 2.1e-164 548.4 0.0 2.4e-164 548.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 OWF42358.1 - 1.6e-164 548.8 0.0 1.9e-164 548.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RhoGAP PF00620.27 OWF42359.1 - 7.6e-47 158.9 0.1 2.5e-46 157.3 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.6 OWF42359.1 - 7.8e-17 61.8 1.2 1.9e-16 60.5 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PDZ_6 PF17820.1 OWF42359.1 - 5.7e-12 45.3 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 OWF42359.1 - 1.4e-11 44.8 0.2 5e-11 43.1 0.2 2.0 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 OWF42359.1 - 5.5e-08 33.1 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF42359.1 - 0.00075 19.8 0.0 0.0031 17.8 0.0 2.0 1 0 0 1 1 1 1 PDZ domain DUF648 PF04890.13 OWF42359.1 - 0.034 13.9 2.5 0.077 12.7 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF648) PH_11 PF15413.6 OWF42359.1 - 0.16 12.4 1.9 0.38 11.2 0.2 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Synaphin PF05835.12 OWF42359.1 - 0.21 11.9 12.3 0.031 14.5 7.0 2.3 2 0 0 2 2 2 0 Synaphin protein HLH PF00010.26 OWF42360.1 - 4.6e-19 68.1 1.1 7.7e-19 67.4 1.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TEX12 PF15219.6 OWF42361.1 - 3.6e-05 24.0 0.0 5.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Testis-expressed 12 Laminin_II PF06009.12 OWF42361.1 - 0.0061 16.6 0.3 0.01 15.8 0.3 1.3 1 0 0 1 1 1 1 Laminin Domain II ApoLp-III PF07464.11 OWF42361.1 - 0.021 14.9 0.3 0.031 14.4 0.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_13 PF13166.6 OWF42361.1 - 0.039 12.6 1.0 0.053 12.2 1.0 1.2 1 0 0 1 1 1 0 AAA domain 7tm_2 PF00002.24 OWF42362.1 - 9.6e-50 169.1 16.3 1.4e-49 168.7 16.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF42362.1 - 8.3e-10 38.8 5.2 8.3e-10 38.8 5.2 2.0 2 0 0 2 2 2 1 Hormone receptor domain RNA_helicase PF00910.22 OWF42363.1 - 0.06 13.7 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Innexin PF00876.18 OWF42364.1 - 4.1e-96 322.3 14.1 5e-96 322.0 14.1 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 OWF42365.1 - 9.3e-104 347.5 11.5 1.2e-103 347.2 11.5 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 OWF42366.1 - 8e-80 268.8 13.8 9.1e-80 268.6 13.8 1.0 1 0 0 1 1 1 1 Innexin Tmemb_18A PF09771.9 OWF42366.1 - 0.012 16.0 5.0 0.54 10.7 0.3 3.1 3 0 0 3 3 3 0 Transmembrane protein 188 Innexin PF00876.18 OWF42367.1 - 8e-60 203.0 8.7 9.1e-60 202.8 8.7 1.0 1 0 0 1 1 1 1 Innexin DUF218 PF02698.17 OWF42368.1 - 2.1e-17 63.4 0.0 3e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain KTSC PF13619.6 OWF42368.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 KTSC domain Pkinase_Tyr PF07714.17 OWF42369.1 - 6.8e-66 222.2 0.0 1e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF42369.1 - 6.2e-61 206.1 0.0 1.2e-60 205.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF42369.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 OWF42369.1 - 0.055 13.1 0.0 7.3 6.1 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OWF42369.1 - 0.069 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family SCRG1 PF15224.6 OWF42371.1 - 0.026 14.6 51.6 0.26 11.4 3.4 6.5 2 1 4 8 8 8 0 Scrapie-responsive protein 1 UQ_con PF00179.26 OWF42374.1 - 4.6e-50 168.9 0.0 5.3e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_topoisoIV PF00521.20 OWF42375.1 - 1.2e-126 423.0 0.1 2.5e-126 422.0 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OWF42375.1 - 1.7e-49 167.3 5.8 6.7e-49 165.4 5.8 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OWF42375.1 - 1e-28 100.0 2.1 2.7e-28 98.6 2.1 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OWF42375.1 - 3.5e-14 53.3 0.0 1.6e-13 51.1 0.0 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OWF42375.1 - 2.2e-08 34.3 0.1 1.5e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 Toprim domain DTHCT PF08070.11 OWF42375.1 - 0.00012 22.8 26.5 0.00012 22.8 26.5 8.0 3 2 4 8 8 8 1 DTHCT (NUC029) region Dynein_attach_N PF15867.5 OWF42376.1 - 9.3e-29 99.2 2.1 1.8e-28 98.2 0.6 2.0 2 0 0 2 2 2 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 OWF42376.1 - 1.1e-18 67.5 0.0 1.8e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 DUF2439 PF10382.9 OWF42376.1 - 0.14 12.5 0.7 9.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Band_7 PF01145.25 OWF42377.1 - 8.9e-09 35.6 0.0 2e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family DnaA_N PF11638.8 OWF42377.1 - 0.035 13.8 1.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 DnaA N-terminal domain DUF5481 PF17578.2 OWF42377.1 - 0.13 12.7 0.1 0.34 11.3 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5481) Phasin PF05597.11 OWF42378.1 - 0.0021 18.0 6.3 0.013 15.5 1.2 2.3 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) CCDC144C PF14915.6 OWF42378.1 - 0.0038 16.4 12.5 0.0064 15.6 12.5 1.4 1 1 0 1 1 1 1 CCDC144C protein coiled-coil region DUF3584 PF12128.8 OWF42378.1 - 0.0087 13.6 11.9 0.0095 13.5 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 OWF42378.1 - 0.0093 14.9 11.4 0.014 14.2 11.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 OWF42378.1 - 0.01 15.7 10.0 0.01 15.7 10.0 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein FlxA PF14282.6 OWF42378.1 - 0.036 14.1 20.1 0.045 13.8 18.5 1.9 1 1 1 2 2 2 0 FlxA-like protein MPS2 PF17060.5 OWF42378.1 - 0.046 13.0 7.6 0.058 12.6 7.6 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Allexi_40kDa PF05549.11 OWF42378.1 - 0.055 13.0 6.3 0.088 12.3 6.2 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein FapA PF03961.13 OWF42378.1 - 0.064 11.8 8.1 0.083 11.5 8.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CortBP2 PF09727.9 OWF42378.1 - 0.07 13.0 12.3 0.11 12.4 12.3 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 Lectin_N PF03954.14 OWF42378.1 - 0.073 12.8 3.1 0.3 10.8 3.0 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain FemAB PF02388.16 OWF42378.1 - 0.088 11.7 4.6 0.11 11.3 4.6 1.3 1 0 0 1 1 1 0 FemAB family DUF2968 PF11180.8 OWF42378.1 - 0.091 12.4 14.9 2.4 7.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CCDC-167 PF15188.6 OWF42378.1 - 0.12 12.7 15.8 0.26 11.6 11.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ax_dynein_light PF10211.9 OWF42378.1 - 0.28 11.1 18.7 0.087 12.8 1.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Exonuc_VII_L PF02601.15 OWF42378.1 - 0.32 10.5 7.6 0.37 10.3 7.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 OWF42378.1 - 0.47 10.9 9.4 0.76 10.2 9.4 1.4 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 OWF42378.1 - 0.48 8.3 7.1 0.62 7.9 7.1 1.0 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.12 OWF42378.1 - 0.49 10.9 2.9 3.4 8.2 1.5 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 OWF42378.1 - 0.77 10.1 18.6 0.55 10.6 12.6 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CorA PF01544.18 OWF42378.1 - 0.86 8.9 5.0 1.7 7.9 5.0 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SlyX PF04102.12 OWF42378.1 - 0.88 10.2 16.1 1.7 9.3 2.4 3.3 1 1 2 3 3 3 0 SlyX Golgin_A5 PF09787.9 OWF42378.1 - 1.1 8.7 19.2 2.1 7.7 18.8 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 CK2S PF15011.6 OWF42378.1 - 1.4 8.8 9.4 5.6 6.8 9.4 1.8 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF4094 PF13334.6 OWF42378.1 - 1.8 9.0 6.6 4.1 7.9 6.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Prefoldin_2 PF01920.20 OWF42378.1 - 2.8 7.9 16.5 3 7.9 9.1 2.9 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.19 OWF42378.1 - 2.9 5.7 13.4 1.4 6.8 11.0 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CSN5_C PF18323.1 OWF42378.1 - 4.2 8.3 9.9 0.72 10.8 3.0 2.5 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Iron_permease PF04120.12 OWF42378.1 - 6.3 6.6 6.2 1.4 8.7 1.4 2.0 1 1 1 2 2 2 0 Low affinity iron permease DUF724 PF05266.14 OWF42378.1 - 7.4 6.3 15.6 3.7 7.3 11.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 OWF42378.1 - 8 6.6 12.1 11 6.2 4.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ly49 PF08391.10 OWF42378.1 - 8.9 6.7 9.4 7.7 6.9 7.6 1.7 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Lipase_GDSL_2 PF13472.6 OWF42379.1 - 2.1e-05 25.0 0.0 2.2e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF42379.1 - 0.0045 17.0 0.0 0.0051 16.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_transf_10 PF00852.19 OWF42380.1 - 3.1e-50 170.3 5.3 5.2e-50 169.6 5.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF42380.1 - 6.2e-18 65.3 1.1 1.1e-17 64.4 0.0 2.0 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal Pkinase_Tyr PF07714.17 OWF42381.1 - 2.4e-89 299.1 0.0 3.1e-89 298.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF42381.1 - 1.2e-44 152.7 0.0 1.6e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 OWF42381.1 - 0.008 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family TMEM154 PF15102.6 OWF42381.1 - 0.017 15.0 0.2 0.017 15.0 0.2 1.5 2 0 0 2 2 2 0 TMEM154 protein family Haspin_kinase PF12330.8 OWF42381.1 - 0.032 13.2 0.0 0.15 11.0 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain DUF2434 PF10361.9 OWF42381.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) FA PF08736.11 OWF42382.1 - 0.014 15.4 5.8 1.2 9.3 0.4 2.8 1 1 2 3 3 3 0 FERM adjacent (FA) Myb_CC_LHEQLE PF14379.6 OWF42382.1 - 0.05 13.3 10.8 14 5.5 0.1 5.3 1 1 3 4 4 4 0 MYB-CC type transfactor, LHEQLE motif DiSB-ORF2_chro PF16506.5 OWF42382.1 - 2.5 8.2 9.8 2e+02 2.0 0.1 4.5 1 1 1 2 2 2 0 Putative virion glycoprotein of insect viruses ERp29_N PF07912.13 OWF42383.1 - 9.7e-35 119.5 0.3 1.7e-34 118.7 0.3 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 OWF42383.1 - 4.2e-23 82.1 1.9 1.1e-22 80.7 1.9 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain VraX PF17412.2 OWF42383.1 - 0.0096 15.5 0.7 0.47 10.1 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function Thioredoxin PF00085.20 OWF42383.1 - 0.044 13.8 0.6 0.11 12.5 0.1 1.9 2 1 0 2 2 2 0 Thioredoxin Ribosomal_60s PF00428.19 OWF42384.1 - 1.2e-25 89.9 13.8 1.4e-25 89.7 13.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Chorion_2 PF03964.15 OWF42384.1 - 0.021 15.7 0.6 0.027 15.3 0.6 1.2 1 0 0 1 1 1 0 Chorion family 2 DUF3824 PF12868.7 OWF42384.1 - 0.044 14.5 2.9 0.059 14.0 2.9 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Med21 PF11221.8 OWF42385.1 - 1.8e-26 93.2 6.5 8.5e-26 90.9 6.5 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex APG6_N PF17675.1 OWF42385.1 - 0.0048 17.4 0.3 0.0048 17.4 0.3 1.4 2 0 0 2 2 2 1 Apg6 coiled-coil region Galactosyl_T PF01762.21 OWF42386.1 - 3.6e-42 144.4 0.9 3.6e-42 144.4 0.9 1.8 2 0 0 2 2 2 1 Galactosyltransferase DAN PF03045.15 OWF42387.1 - 1.3e-36 125.0 8.3 2e-36 124.4 8.3 1.2 1 0 0 1 1 1 1 DAN domain Fer2_2 PF01799.20 OWF42387.1 - 0.055 13.5 0.4 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 [2Fe-2S] binding domain RVT_2 PF07727.14 OWF42389.1 - 0.016 14.9 6.6 4.2 6.9 0.1 4.0 1 1 3 4 4 4 0 Reverse transcriptase (RNA-dependent DNA polymerase) B_solenoid_dext PF18841.1 OWF42389.1 - 0.43 10.9 7.2 3.4e+02 1.7 0.0 5.7 3 3 5 8 8 8 0 Beta solenoid repeat from Dextranase HcyBio PF01837.16 OWF42389.1 - 5.4 5.7 14.9 1.8 7.3 1.0 2.9 1 1 2 3 3 3 0 Homocysteine biosynthesis enzyme, sulfur-incorporation 7TM_GPCR_Srw PF10324.9 OWF42390.1 - 4.3e-33 114.9 33.0 5.3e-33 114.6 33.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF42390.1 - 9.1e-13 48.1 23.0 1.4e-12 47.5 23.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EI24 PF07264.11 OWF42390.1 - 0.00025 21.4 3.3 0.00025 21.4 3.3 1.8 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) 7TM_GPCR_Srx PF10328.9 OWF42390.1 - 0.0049 16.5 27.5 0.0049 16.5 27.5 2.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Methyltransf_25 PF13649.6 OWF42391.1 - 2e-13 50.9 0.0 3.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF42391.1 - 1.8e-12 47.4 0.0 3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF42391.1 - 7.9e-11 42.5 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF42391.1 - 1.8e-09 37.3 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OWF42391.1 - 2.2e-07 30.8 0.1 1.1e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF42391.1 - 7.7e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OWF42391.1 - 0.00045 20.9 0.0 0.0011 19.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OWF42391.1 - 0.0032 17.5 0.0 0.0063 16.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 OWF42391.1 - 0.0035 16.0 0.0 0.021 13.4 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 OWF42391.1 - 0.0059 16.0 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 OWF42391.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Docking PF08990.11 OWF42392.1 - 0.31 10.7 0.1 0.31 10.7 0.1 2.0 2 0 0 2 2 2 0 Erythronolide synthase docking Claudin_2 PF13903.6 OWF42393.1 - 1e-12 48.2 12.9 1.9e-12 47.3 12.9 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction NOA36 PF06524.12 OWF42393.1 - 0.15 11.3 0.4 0.21 10.9 0.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3796 PF12676.7 OWF42393.1 - 1.2 9.6 7.1 0.14 12.6 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF4569 PF15133.6 OWF42394.1 - 0.00019 21.2 3.9 13 5.4 0.1 5.7 1 1 5 6 6 6 2 Domain of unknown function (DUF4569) Sua5_yciO_yrdC PF01300.18 OWF42394.1 - 0.0053 16.3 12.7 1.4 8.4 0.5 4.9 1 1 3 4 4 4 3 Telomere recombination DUF2685 PF10886.8 OWF42394.1 - 1.5 9.1 43.8 80 3.5 0.1 14.5 2 2 16 18 18 18 0 Protein of unknown function (DUF2685) HicA_toxin PF07927.12 OWF42394.1 - 5.8 7.0 12.3 57 3.9 0.0 6.6 4 3 6 10 10 10 0 HicA toxin of bacterial toxin-antitoxin, Rhodanese_C PF12368.8 OWF42394.1 - 7 7.1 38.6 81 3.7 1.6 7.0 1 1 3 4 4 4 0 Rhodanase C-terminal DAGK_cat PF00781.24 OWF42395.1 - 1.1e-21 76.8 0.0 1.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 OWF42395.1 - 1.8e-11 44.6 0.0 2.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.22 OWF42395.1 - 9.8e-05 22.2 9.1 9.8e-05 22.2 9.1 2.5 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TIMP PF00965.17 OWF42396.1 - 0.0002 21.3 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF42396.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Apolipoprotein PF01442.18 OWF42397.1 - 3.8e-38 131.3 3.4 4.5e-08 33.2 0.0 5.0 1 1 1 3 3 3 3 Apolipoprotein A1/A4/E domain CsbD PF05532.12 OWF42397.1 - 1.3e-27 95.4 11.3 21 5.1 0.0 20.0 1 1 28 29 29 29 0 CsbD-like PKHD_C PF18331.1 OWF42397.1 - 4.3e-12 45.9 29.5 4.8e+02 0.9 0.0 24.0 1 1 28 29 29 29 0 PKHD-type hydroxylase C-terminal domain DUF4455 PF14643.6 OWF42397.1 - 2.9e-09 36.1 22.7 1.4 7.4 0.1 7.2 1 1 6 8 8 8 8 Domain of unknown function (DUF4455) Vps54 PF07928.12 OWF42397.1 - 1.1e-06 29.1 49.4 59 4.1 0.8 16.1 1 1 21 22 22 22 0 Vps54-like protein Elf4 PF07011.11 OWF42397.1 - 9.3e-06 25.5 59.7 35 4.4 0.2 13.6 1 1 27 28 28 28 0 Early Flowering 4 domain CBM_6 PF03422.15 OWF42397.1 - 0.0065 16.8 63.5 21 5.4 0.5 10.6 1 1 21 22 22 22 0 Carbohydrate binding module (family 6) RasGAP PF00616.19 OWF42397.1 - 0.12 12.0 24.0 5.6e+02 0.1 7.5 6.2 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase PCC_BT PF18140.1 OWF42397.1 - 0.62 10.4 50.5 18 5.7 1.9 7.8 1 1 8 9 9 9 0 Propionyl-coenzyme A carboxylase BT domain EF-hand_7 PF13499.6 OWF42398.1 - 9.2e-28 96.5 21.3 1.2e-06 28.9 0.0 7.3 5 1 0 6 6 6 6 EF-hand domain pair EF-hand_11 PF08976.11 OWF42398.1 - 3.8e-27 95.2 8.0 6.2e-09 36.7 0.0 6.9 7 0 0 7 7 7 5 EF-hand domain EF-hand_8 PF13833.6 OWF42398.1 - 1e-25 89.3 11.4 2.2e-06 27.4 0.0 7.7 7 1 1 8 8 8 5 EF-hand domain pair EF-hand_1 PF00036.32 OWF42398.1 - 1.4e-19 68.1 11.9 0.0032 16.9 0.0 11.0 11 0 0 11 11 11 7 EF hand EF-hand_6 PF13405.6 OWF42398.1 - 5.2e-16 57.2 8.0 0.024 14.6 0.0 10.2 11 0 0 11 11 11 4 EF-hand domain DUF5580 PF17743.1 OWF42398.1 - 6.7e-08 31.5 1.4 0.0031 16.1 0.0 4.3 4 2 0 4 4 4 3 Family of unknown function (DUF5580) EF-hand_5 PF13202.6 OWF42398.1 - 5.6e-05 22.4 0.4 6.8 6.4 0.0 6.0 6 0 0 6 6 6 1 EF hand GPHH PF16905.5 OWF42398.1 - 0.1 12.4 0.0 0.9 9.4 0.0 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Spore_III_AB PF09548.10 OWF42398.1 - 0.16 12.1 1.6 9.5 6.3 0.0 3.3 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) UCH PF00443.29 OWF42399.1 - 2.3e-35 122.3 0.6 4.3e-35 121.4 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OWF42399.1 - 6.8e-12 45.5 2.5 1.4e-11 44.5 2.5 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OWF42399.1 - 0.0059 16.2 2.1 0.0059 16.2 2.1 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UPF0561 PF10573.9 OWF42400.1 - 0.0004 20.5 0.9 0.51 10.5 0.1 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0561 Piwi PF02171.17 OWF42401.1 - 9.4e-93 310.8 0.1 1.6e-92 310.0 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 OWF42401.1 - 2.5e-32 111.6 0.1 4.4e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 OWF42401.1 - 0.0018 17.9 0.0 0.0055 16.4 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain IMS PF00817.20 OWF42401.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family 7tm_2 PF00002.24 OWF42402.1 - 3.8e-22 78.8 22.3 3.8e-22 78.8 22.3 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 OWF42402.1 - 0.22 10.5 22.0 0.012 14.7 15.9 2.0 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region Somatomedin_B PF01033.17 OWF42402.1 - 0.78 10.2 18.2 0.15 12.5 11.5 3.2 2 0 0 2 2 2 0 Somatomedin B domain PKD_channel PF08016.12 OWF42403.1 - 4.5e-146 486.9 16.9 4.5e-146 486.9 16.9 1.8 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 OWF42403.1 - 3.2e-26 92.1 30.7 4.6e-26 91.5 27.4 2.1 2 0 0 2 2 2 1 Ion transport protein Fer4_24 PF18109.1 OWF42403.1 - 4.7e-09 36.4 0.2 9.9e-09 35.3 0.2 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_1 PF00036.32 OWF42403.1 - 4.9e-06 25.7 2.1 0.02 14.4 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OWF42403.1 - 0.015 15.8 7.4 3.3 8.2 0.1 4.1 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.6 OWF42403.1 - 0.031 14.2 1.5 3 8.0 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain THOC7 PF05615.13 OWF42403.1 - 0.27 11.5 6.2 1.4 9.2 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 PGM_PMM_I PF02878.16 OWF42405.1 - 0.25 11.1 0.4 23 4.7 0.1 2.4 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF1910 PF08928.10 OWF42405.1 - 1.3 9.0 7.3 35 4.4 0.2 4.1 1 1 4 5 5 5 0 Domain of unknown function (DUF1910) H2TH PF06831.14 OWF42406.1 - 5.5e-12 45.5 0.1 1.6e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 OWF42406.1 - 4.3e-05 24.1 0.0 7.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Trypsin PF00089.26 OWF42408.1 - 3.8e-36 125.0 4.9 4.2e-36 124.8 4.9 1.0 1 0 0 1 1 1 1 Trypsin VCBS PF13517.6 OWF42409.1 - 5.2e-12 46.2 8.2 0.0012 19.4 0.2 3.8 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OWF42409.1 - 1.5e-08 34.6 5.9 0.0044 17.1 0.5 3.7 3 0 0 3 3 3 3 FG-GAP repeat PliI PF16743.5 OWF42409.1 - 5.2e-05 23.0 0.0 0.022 14.5 0.0 3.2 3 1 0 3 3 3 2 Periplasmic lysozyme inhibitor of I-type lysozyme VioE PF18234.1 OWF42410.1 - 0.021 15.0 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE AIG1 PF04548.16 OWF42411.1 - 2.4e-60 203.5 0.0 2.4e-60 203.5 0.0 2.6 3 0 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 OWF42411.1 - 2.2e-07 30.9 0.1 9.8e-07 28.9 0.1 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF42411.1 - 0.00033 20.2 0.1 0.00064 19.3 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF42411.1 - 0.00049 20.0 0.1 0.0017 18.3 0.1 2.0 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 OWF42411.1 - 0.031 13.3 0.0 0.088 11.9 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein HAUS-augmin3 PF14932.6 OWF42411.1 - 0.74 9.3 16.2 2.3 7.7 16.2 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ubiquitin PF00240.23 OWF42411.1 - 0.91 9.3 4.5 1.2 9.0 0.0 3.7 4 1 0 4 4 4 0 Ubiquitin family Aft1_HRA PF11786.8 OWF42411.1 - 1.7 9.0 13.6 9.7 6.6 0.1 4.8 3 1 0 3 3 3 0 Aft1 HRA domain ubiquitin PF00240.23 OWF42412.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family AIG1 PF04548.16 OWF42414.1 - 3.5e-64 216.0 0.2 3.5e-64 216.0 0.2 3.2 1 1 2 4 4 4 1 AIG1 family MMR_HSR1 PF01926.23 OWF42414.1 - 2.4e-08 34.1 0.0 2.4e-08 34.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF42414.1 - 2.6e-05 23.8 0.0 7.8e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF42414.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 3.2 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 OWF42414.1 - 0.49 10.4 0.0 0.49 10.4 0.0 5.5 3 1 2 5 5 5 0 Dynamin family Ependymin PF00811.18 OWF42415.1 - 3.5e-28 98.4 0.2 5.1e-28 97.9 0.2 1.2 1 0 0 1 1 1 1 Ependymin YaiA PF16362.5 OWF42415.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 YaiA protein COesterase PF00135.28 OWF42416.1 - 7.6e-113 378.1 0.0 8.8e-113 377.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF42416.1 - 4e-05 23.6 0.1 0.00013 21.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold AJAP1_PANP_C PF15298.6 OWF42416.1 - 0.27 11.4 9.5 0.5 10.6 9.5 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.17 OWF42416.1 - 7.2 6.6 25.3 13 5.8 25.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 OWF42416.1 - 7.9 6.5 20.1 16 5.5 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 OWF42416.1 - 9.1 4.1 7.8 13 3.6 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cas1_AcylT PF07779.12 OWF42418.1 - 9.9e-210 697.4 35.6 1.6e-209 696.8 35.6 1.3 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p AMP-binding PF00501.28 OWF42419.1 - 3.8e-63 213.5 0.0 4.5e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF42419.1 - 1.2e-06 29.4 0.0 2.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IDO PF01231.18 OWF42420.1 - 6.7e-43 147.1 0.0 8.3e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TM1586_NiRdase PF14512.6 OWF42420.1 - 0.023 14.2 0.7 0.98 8.9 0.3 2.3 2 0 0 2 2 2 0 Putative TM nitroreductase Plasmodium_Vir PF05795.11 OWF42420.1 - 0.033 13.6 0.8 0.043 13.2 0.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1133 PF06576.11 OWF42420.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) DUF1864 PF08933.11 OWF42420.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.19 OWF42421.1 - 2.1e-10 40.1 0.0 3.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OWF42421.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family EGF PF00008.27 OWF42422.1 - 1.6e-05 25.1 4.9 4.4e-05 23.7 4.9 1.8 1 0 0 1 1 1 1 EGF-like domain SEA PF01390.20 OWF42422.1 - 0.00084 19.4 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 SEA domain Adeno_E3_CR2 PF02439.15 OWF42422.1 - 0.056 13.2 0.6 0.1 12.4 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EGF_CA PF07645.15 OWF42422.1 - 0.43 10.8 14.8 0.68 10.2 8.7 2.5 1 1 1 2 2 2 0 Calcium-binding EGF domain EGF_3 PF12947.7 OWF42422.1 - 1.7 8.9 10.9 4.5 7.6 10.9 1.8 1 0 0 1 1 1 0 EGF domain SEA PF01390.20 OWF42423.1 - 1.6e-05 24.9 0.1 4.8e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 SEA domain ETRAMP PF09716.10 OWF42423.1 - 0.027 14.5 0.2 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) hEGF PF12661.7 OWF42423.1 - 4 8.2 10.9 0.27 11.9 4.7 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF DUF3592 PF12158.8 OWF42424.1 - 0.086 12.9 0.1 0.28 11.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) Patatin PF01734.22 OWF42424.1 - 0.17 12.0 0.6 0.24 11.6 0.6 1.3 1 1 0 1 1 1 0 Patatin-like phospholipase Myb_DNA-bind_4 PF13837.6 OWF42425.1 - 4.9e-11 42.9 4.3 4.9e-11 42.9 4.3 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OWF42425.1 - 1e-06 29.6 2.0 1e-06 29.6 2.0 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OWF42425.1 - 0.011 15.8 4.6 0.011 15.8 4.6 2.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OWF42425.1 - 0.021 15.1 0.9 0.021 15.1 0.9 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF573 PF04504.14 OWF42425.1 - 0.03 15.0 2.7 0.21 12.2 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Repressor_Mnt PF11423.8 OWF42427.1 - 0.15 11.9 0.7 79 3.2 0.0 4.5 3 1 1 4 4 4 0 Regulatory protein Mnt SEA PF01390.20 OWF42429.1 - 1.2e-07 31.7 0.1 2.9e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 SEA domain Orthoreo_P10 PF07204.11 OWF42429.1 - 0.017 15.0 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TMEM154 PF15102.6 OWF42429.1 - 0.018 14.9 0.1 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 OWF42429.1 - 0.025 15.5 0.6 0.047 14.6 0.2 1.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OWF42429.1 - 0.032 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DUF5385 PF17359.2 OWF42429.1 - 0.08 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DAP10 PF07213.11 OWF42429.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein S_locus_glycop PF00954.20 OWF42429.1 - 0.13 12.8 13.2 2.2 8.9 5.6 2.6 1 1 1 2 2 2 0 S-locus glycoprotein domain FGFR3_TM PF18123.1 OWF42429.1 - 0.13 11.8 5.7 0.25 10.9 5.7 1.5 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain Plasmod_Pvs28 PF06247.11 OWF42429.1 - 1.5 9.2 9.6 0.15 12.4 1.7 2.5 1 1 1 2 2 2 0 Pvs28 EGF domain COR PF16095.5 OWF42432.1 - 3.4e-21 75.9 0.3 6.3e-21 75.1 0.3 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF42432.1 - 5.6e-08 33.0 0.1 8.6e-07 29.2 0.0 2.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Sulfotransfer_1 PF00685.27 OWF42433.1 - 1.5e-12 47.6 1.3 3.7e-12 46.3 1.3 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF42433.1 - 6.5e-11 43.0 0.0 1.5e-09 38.6 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family Kazal_1 PF00050.21 OWF42433.1 - 0.2 11.7 3.9 0.28 11.2 0.4 2.2 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain RTA1 PF04479.13 OWF42434.1 - 0.4 10.2 11.3 0.4 10.3 0.2 3.5 2 1 2 4 4 4 0 RTA1 like protein Defensin_big PF14862.6 OWF42434.1 - 2.1 8.7 6.9 6.5 7.1 0.1 3.3 2 1 0 2 2 2 0 Big defensin FA PF08736.11 OWF42435.1 - 0.0032 17.5 17.5 8 6.6 0.7 5.7 1 1 7 8 8 8 8 FERM adjacent (FA) DUF3454 PF11936.8 OWF42435.1 - 0.015 15.7 15.5 11 6.5 0.4 5.2 1 1 3 4 4 4 0 Domain of unknown function (DUF3454) VHL_C PF17211.3 OWF42436.1 - 0.058 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 VHL box domain APG6 PF04111.12 OWF42436.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Apg6 BARA domain Put_DNA-bind_N PF06971.13 OWF42436.1 - 0.47 10.5 3.4 0.93 9.6 0.0 2.7 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus C1q PF00386.21 OWF42437.1 - 4.5e-17 62.5 0.1 7.6e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 OWF42439.1 - 1.9e-12 47.5 0.1 3.6e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 C1q domain LPMO_10 PF03067.15 OWF42440.1 - 1.1e-34 120.8 0.0 1.6e-34 120.3 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading VWA PF00092.28 OWF42441.1 - 1.8e-42 145.5 0.1 2.7e-42 145.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF42441.1 - 2.3e-19 69.3 17.5 2.5e-05 24.3 0.2 4.7 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain VWA_2 PF13519.6 OWF42441.1 - 1.2e-16 61.3 0.0 2.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain SARS_X4 PF08779.10 OWF42441.1 - 0.021 15.0 1.0 0.15 12.3 1.0 2.4 1 0 0 1 1 1 0 SARS coronavirus X4 like Phi29_Phage_SSB PF17427.2 OWF42441.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Kazal_2 PF07648.15 OWF42442.1 - 8.9e-10 38.5 12.3 6.8e-06 26.1 1.9 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF42442.1 - 1.2e-06 28.4 16.9 0.0015 18.5 4.6 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF42443.1 - 4.7e-12 45.7 16.4 2.7e-06 27.3 3.0 2.6 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF42443.1 - 6.6e-10 39.0 13.3 4.5e-05 23.5 1.6 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain TssO PF17561.2 OWF42444.1 - 0.012 15.7 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO Ly49 PF08391.10 OWF42444.1 - 0.029 14.7 0.5 0.029 14.7 0.5 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF4834 PF16118.5 OWF42444.1 - 0.075 14.0 1.8 0.85 10.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Cadherin_C_2 PF16492.5 OWF42444.1 - 0.56 11.0 6.9 1.3 9.8 6.9 2.0 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal LST1 PF05083.13 OWF42444.1 - 0.61 10.4 2.3 4.6 7.6 0.3 2.5 2 0 0 2 2 2 0 LST-1 protein Shisa PF13908.6 OWF42444.1 - 1.2 9.3 3.3 0.58 10.4 0.5 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ig_3 PF13927.6 OWF42445.1 - 1.3e-170 554.4 139.2 2.8e-09 37.4 0.5 30.2 31 0 0 31 31 30 25 Immunoglobulin domain I-set PF07679.16 OWF42445.1 - 1.4e-142 464.2 51.1 4.3e-10 39.5 0.1 28.3 28 1 0 28 28 28 19 Immunoglobulin I-set domain C2-set_2 PF08205.12 OWF42445.1 - 2.2e-134 437.9 62.8 2.7e-11 43.4 0.0 25.5 26 0 0 26 26 25 21 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 OWF42445.1 - 8e-111 362.6 116.3 2.7e-07 30.8 0.0 29.0 29 0 0 29 29 29 22 Immunoglobulin domain ig PF00047.25 OWF42445.1 - 3.3e-92 302.8 123.4 2.5e-09 37.2 0.1 28.5 27 1 0 27 27 27 19 Immunoglobulin domain C1-set PF07654.15 OWF42445.1 - 2.9e-36 123.7 70.0 0.00017 21.9 0.4 22.9 24 0 0 24 24 23 9 Immunoglobulin C1-set domain V-set PF07686.17 OWF42445.1 - 5e-16 58.8 67.3 9.2e-05 22.6 1.0 20.7 18 9 0 18 18 17 3 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF42445.1 - 4.9e-14 52.4 16.4 0.15 12.3 0.0 13.4 14 2 0 14 14 13 3 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 OWF42445.1 - 4e-13 48.7 4.0 0.19 11.3 0.0 9.4 8 0 0 8 8 8 3 Immunoglobulin domain Ig_5 PF16681.5 OWF42445.1 - 2.4e-10 40.7 16.6 2.4 8.6 0.0 13.6 16 0 0 16 16 14 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 OWF42445.1 - 1.2e-05 25.4 7.3 8.7 6.6 0.0 10.9 13 0 0 13 13 12 1 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 OWF42445.1 - 1.4e-05 24.8 32.2 0.072 12.9 0.3 10.3 10 0 0 10 10 10 3 Adenovirus E3 region protein CR1 CYYR1 PF10873.8 OWF42445.1 - 0.0066 16.9 0.1 0.023 15.1 0.1 1.9 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Shisa PF13908.6 OWF42445.1 - 0.017 15.3 0.3 0.08 13.2 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.6 OWF42445.1 - 0.13 12.6 0.0 0.46 10.8 0.0 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EphA2_TM PF14575.6 OWF42445.1 - 0.34 11.8 0.0 0.34 11.8 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.6 OWF42446.1 - 1e-41 141.4 30.7 6.7e-13 49.0 0.5 6.0 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 OWF42446.1 - 1.5e-39 134.2 32.7 2.1e-11 44.0 1.9 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 OWF42446.1 - 1.2e-30 105.4 15.1 2.5e-10 40.3 0.0 6.9 5 2 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 OWF42446.1 - 2.9e-18 65.8 39.7 3.7e-08 33.4 2.5 7.2 6 2 0 6 6 6 3 Immunoglobulin domain C2-set_2 PF08205.12 OWF42446.1 - 3.7e-18 65.4 13.5 7.8e-08 32.3 0.6 4.8 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF42446.1 - 6.3e-11 42.4 24.0 0.033 14.3 0.2 7.5 5 3 2 7 7 7 4 Immunoglobulin V-set domain Shisa PF13908.6 OWF42446.1 - 3e-06 27.6 0.3 3e-06 27.6 0.3 3.0 4 0 0 4 4 2 1 Wnt and FGF inhibitory regulator C1-set PF07654.15 OWF42446.1 - 1.5e-05 25.3 6.0 0.02 15.3 0.3 4.3 5 0 0 5 5 4 1 Immunoglobulin C1-set domain CYYR1 PF10873.8 OWF42446.1 - 0.001 19.6 0.2 0.0038 17.7 0.2 2.0 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 OAD_gamma PF04277.13 OWF42446.1 - 0.0018 18.8 0.0 0.0063 17.1 0.0 1.9 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.6 OWF42446.1 - 0.0028 18.5 0.0 0.0028 18.5 0.0 2.7 2 1 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OWF42446.1 - 0.0055 17.4 0.0 0.041 14.6 0.0 2.6 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Prominin PF05478.11 OWF42446.1 - 0.0071 14.4 1.5 0.01 13.8 1.5 1.1 1 0 0 1 1 1 1 Prominin FAM163 PF15069.6 OWF42446.1 - 0.0081 16.6 1.8 0.083 13.3 0.1 2.8 2 0 0 2 2 2 1 FAM163 family Ig_6 PF18452.1 OWF42446.1 - 0.0084 15.7 0.1 0.37 10.4 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain TMEM154 PF15102.6 OWF42446.1 - 0.0085 16.0 0.0 0.0085 16.0 0.0 3.2 3 0 0 3 3 2 1 TMEM154 protein family ETRAMP PF09716.10 OWF42446.1 - 0.011 15.8 0.6 0.025 14.7 0.6 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PROL5-SMR PF15621.6 OWF42446.1 - 0.012 16.2 0.1 0.059 13.9 0.1 2.2 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Protocadherin PF08374.11 OWF42446.1 - 0.016 15.2 0.0 0.016 15.2 0.0 2.6 2 0 0 2 2 1 0 Protocadherin Comm PF15957.5 OWF42446.1 - 0.035 14.4 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 Commissureless SIT PF15330.6 OWF42446.1 - 0.062 13.8 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Receptor_2B4 PF11465.8 OWF42446.1 - 0.077 13.2 2.7 5.6 7.2 0.0 3.0 2 1 1 3 3 2 0 Natural killer cell receptor 2B4 TMIE PF16038.5 OWF42446.1 - 0.23 11.3 2.2 0.48 10.3 2.2 1.5 1 0 0 1 1 1 0 TMIE protein FAM176 PF14851.6 OWF42446.1 - 1.1 8.9 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 1 0 FAM176 family Ig_C17orf99 PF17736.1 OWF42446.1 - 1.9 8.6 11.2 6.9 6.8 0.1 5.3 4 2 0 4 4 4 0 C17orf99 Ig domain CDC45 PF02724.14 OWF42446.1 - 2.3 6.4 12.4 3.4 5.8 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4834 PF16118.5 OWF42446.1 - 2.4 9.2 0.0 2.4 9.2 0.0 3.7 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) Adeno_E3_CR1 PF02440.15 OWF42446.1 - 6 6.7 11.0 0.14 12.0 0.2 3.7 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 FGF-BP1 PF06473.12 OWF42446.1 - 7.9 6.2 11.1 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Ig_3 PF13927.6 OWF42447.1 - 4.9e-68 225.7 62.5 1.6e-10 41.4 2.1 8.5 8 0 0 8 8 8 8 Immunoglobulin domain I-set PF07679.16 OWF42447.1 - 1.3e-57 191.8 23.4 3.1e-09 36.8 0.3 8.9 8 1 0 8 8 8 7 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF42447.1 - 5.7e-48 161.2 59.7 1.7e-08 34.6 1.9 8.3 8 0 0 8 8 8 7 Immunoglobulin domain ig PF00047.25 OWF42447.1 - 1.6e-40 137.1 61.2 1.3e-07 31.7 0.4 8.9 8 1 0 8 8 8 7 Immunoglobulin domain V-set PF07686.17 OWF42447.1 - 1.9e-25 89.1 49.3 3.7e-09 36.7 3.2 11.6 7 5 2 9 9 9 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF42447.1 - 3.3e-20 71.9 35.2 1.7e-11 44.0 0.4 6.7 7 1 1 8 8 7 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF42447.1 - 1.6e-14 54.0 8.8 0.019 15.3 0.1 7.6 7 2 0 7 7 6 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 OWF42447.1 - 1.4e-10 41.3 9.3 0.26 11.6 0.1 8.4 7 3 0 7 7 7 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 OWF42447.1 - 3.8e-08 33.3 0.3 1.1 9.3 0.0 6.1 5 1 2 7 7 7 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 OWF42447.1 - 3e-07 30.7 24.4 5.5e-06 26.7 0.2 7.6 8 0 0 8 8 8 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 OWF42447.1 - 3.8e-05 23.2 5.1 1.2 8.8 0.0 5.1 6 0 0 6 6 6 1 Immunoglobulin domain Stevor PF17410.2 OWF42447.1 - 0.016 14.8 2.1 0.04 13.5 2.1 1.7 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FAM163 PF15069.6 OWF42447.1 - 0.048 14.1 0.5 0.048 14.1 0.5 2.6 3 0 0 3 3 1 0 FAM163 family ETRAMP PF09716.10 OWF42447.1 - 0.09 12.8 0.4 0.21 11.7 0.4 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 OWF42447.1 - 0.8 10.6 0.0 0.8 10.6 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF42447.1 - 0.99 9.3 0.0 0.99 9.3 0.0 3.7 3 0 0 3 3 2 0 TMEM154 protein family Ig_C17orf99 PF17736.1 OWF42447.1 - 1.1 9.3 25.4 5.2 7.2 0.1 7.2 7 1 0 7 7 6 0 C17orf99 Ig domain DUF4834 PF16118.5 OWF42447.1 - 3.1 8.8 8.0 38 5.3 3.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM52 PF14979.6 OWF42447.1 - 3.6 7.5 8.3 0.59 10.0 2.1 2.8 2 0 0 2 2 2 0 Transmembrane 52 Sod_Cu PF00080.20 OWF42448.1 - 1.6e-28 99.6 4.9 1.6e-28 99.6 4.9 4.1 3 1 1 4 4 4 1 Copper/zinc superoxide dismutase (SODC) ZapB PF06005.12 OWF42448.1 - 0.0075 16.7 0.2 0.017 15.6 0.2 1.5 1 0 0 1 1 1 1 Cell division protein ZapB TolA_bind_tri PF16331.5 OWF42448.1 - 0.025 14.7 1.0 0.073 13.2 1.0 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation MbeD_MobD PF04899.12 OWF42448.1 - 0.032 14.4 0.5 0.065 13.3 0.5 1.5 1 0 0 1 1 1 0 MbeD/MobD like DivIC PF04977.15 OWF42448.1 - 0.11 12.3 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Seryl_tRNA_N PF02403.22 OWF42448.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Polysacc_synt PF01943.17 OWF42449.1 - 0.016 14.6 17.2 1.5 8.1 0.6 4.4 1 1 3 4 4 4 0 Polysaccharide biosynthesis protein DUF1324 PF07038.11 OWF42449.1 - 0.57 10.5 47.7 16 5.8 0.8 9.7 1 1 6 8 8 8 0 Protein of unknown function (DUF1324) Pkinase PF00069.25 OWF42450.1 - 6e-41 140.6 0.0 6.7e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42450.1 - 9.9e-20 70.9 0.0 1.1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF42450.1 - 7.3e-06 25.5 0.0 1.4e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF42450.1 - 0.00088 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF42450.1 - 0.056 12.2 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF3603 PF12227.8 OWF42451.1 - 0.0015 17.9 4.8 15 4.8 0.1 4.7 1 1 6 7 7 7 5 Protein of unknown function (DUF3603) RRM_occluded PF16842.5 OWF42451.1 - 0.0036 17.1 0.0 48 3.9 0.0 3.9 1 1 4 5 5 5 4 Occluded RNA-recognition motif Izumo-Ig PF16706.5 OWF42451.1 - 0.34 11.0 2.6 2.7e+02 1.7 0.0 4.8 1 1 6 7 7 7 0 Izumo-like Immunoglobulin domain Death PF00531.22 OWF42452.1 - 0.00096 19.3 0.4 0.0059 16.7 0.0 2.5 2 0 0 2 2 2 1 Death domain SesA PF17107.5 OWF42452.1 - 0.32 11.2 3.6 0.51 10.5 0.4 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4208 PF13907.6 OWF42452.1 - 0.7 10.4 8.1 1.1 9.7 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4208) DUF745 PF05335.13 OWF42452.1 - 1.3 8.7 6.0 5.5 6.7 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) SNF PF00209.18 OWF42453.1 - 1.4e-195 651.0 27.9 1.8e-195 650.6 27.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family MAPEG PF01124.18 OWF42454.1 - 2e-06 27.7 0.4 2e-06 27.7 0.4 1.5 2 0 0 2 2 2 1 MAPEG family 7tm_1 PF00001.21 OWF42455.1 - 4.2e-23 82.0 23.3 4.9e-23 81.8 23.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF42455.1 - 3e-06 27.1 27.9 4.4e-06 26.5 27.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PIF1 PF05970.14 OWF42456.1 - 1e-25 90.7 0.0 1.1e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OWF42456.1 - 2.5e-14 53.4 0.0 2.8e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF42456.1 - 1.6e-10 41.5 0.0 1.8e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF42456.1 - 6.3e-07 29.7 1.5 1.5e-05 25.2 1.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OWF42456.1 - 0.00018 21.9 0.2 0.00025 21.5 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 OWF42456.1 - 0.0026 17.7 1.1 0.021 14.7 1.1 2.0 1 1 0 1 1 1 1 NTPase IstB_IS21 PF01695.17 OWF42456.1 - 0.0027 17.5 0.6 1 9.1 0.0 2.2 1 1 1 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 OWF42456.1 - 0.0096 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 OWF42456.1 - 0.0097 15.8 0.1 0.018 15.0 0.0 1.5 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 OWF42456.1 - 0.013 14.9 0.2 0.029 13.7 0.2 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OWF42456.1 - 0.013 15.5 0.6 0.21 11.6 0.6 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OWF42456.1 - 0.021 14.7 0.3 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 OWF42456.1 - 0.023 13.9 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 OWF42456.1 - 0.032 14.7 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OWF42456.1 - 0.034 14.7 0.2 0.045 14.3 0.2 1.4 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OWF42456.1 - 0.043 13.3 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AFG1_ATPase PF03969.16 OWF42456.1 - 0.045 12.6 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase RNA_helicase PF00910.22 OWF42456.1 - 0.046 14.1 0.1 0.069 13.5 0.1 1.7 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 OWF42456.1 - 0.073 13.1 0.2 2.2 8.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 OWF42456.1 - 0.13 12.0 0.7 1.3 8.7 0.7 2.0 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 OWF42456.1 - 0.14 12.0 0.1 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF42456.1 - 0.17 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 OWF42456.1 - 0.17 10.7 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 OWF42456.1 - 0.24 10.4 0.1 0.35 9.9 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 OWF42456.1 - 0.29 10.7 0.9 0.97 9.0 0.2 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VirE PF05272.11 OWF42457.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E SET PF00856.28 OWF42459.1 - 1.7e-12 48.0 1.1 1.1e-11 45.5 0.2 2.6 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 OWF42459.1 - 4.6e-08 33.0 43.1 1.2e-07 31.7 14.6 3.8 3 1 1 4 4 4 2 MYND finger TPR_19 PF14559.6 OWF42459.1 - 4e-06 27.2 0.0 2.1 8.9 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42459.1 - 8.2e-06 25.6 2.4 0.37 11.0 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF42459.1 - 0.00088 19.5 0.2 0.18 12.1 0.0 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF42459.1 - 0.0019 18.0 3.3 1.6 8.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF42459.1 - 0.0094 15.6 0.2 4.2 7.1 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 OWF42459.1 - 0.021 15.0 2.0 15 6.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF42459.1 - 0.024 14.6 1.2 15 5.9 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF42459.1 - 0.057 14.3 0.1 22 6.2 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF42459.1 - 0.081 13.3 0.0 1.3 9.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 OWF42459.1 - 0.56 10.6 1.8 48 4.5 0.0 3.6 4 0 0 4 4 4 0 PPR repeat ANAPC3 PF12895.7 OWF42459.1 - 1.5 9.1 0.0 1.5 9.1 0.0 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-MYND PF01753.18 OWF42460.1 - 1e-11 44.7 38.7 6.4e-06 26.2 22.0 3.4 2 1 0 2 2 2 2 MYND finger SET PF00856.28 OWF42460.1 - 5.1e-11 43.3 0.0 1.6e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 SET domain TPR_19 PF14559.6 OWF42460.1 - 4.3e-06 27.1 0.1 0.0034 17.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42460.1 - 9.4e-05 22.3 12.8 0.58 10.4 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF42460.1 - 0.00012 22.2 2.0 0.07 13.4 0.2 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OWF42460.1 - 0.00027 21.5 0.5 2.8 8.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF42460.1 - 0.00031 20.4 8.6 2 8.4 0.2 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 OWF42460.1 - 0.0056 17.0 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF42460.1 - 0.012 15.8 7.9 1.1 9.7 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF42460.1 - 0.035 14.4 0.6 22 5.4 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Neur_chan_LBD PF02931.23 OWF42461.1 - 2.6e-11 43.4 1.1 4.5e-11 42.6 1.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF42461.1 - 4.5e-07 30.2 7.3 5.6e-07 29.9 6.3 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Clc-like PF07062.12 OWF42461.1 - 0.019 14.5 0.8 0.019 14.5 0.8 2.0 1 1 1 2 2 2 0 Clc-like DUF2070 PF09843.9 OWF42461.1 - 0.073 11.4 6.1 0.1 10.9 6.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YjbH PF06082.11 OWF42461.1 - 0.097 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Phage_holin_2_2 PF10746.9 OWF42461.1 - 0.11 12.2 0.7 0.22 11.2 0.7 1.5 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II DUF4481 PF14800.6 OWF42461.1 - 0.4 10.1 5.5 0.63 9.5 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF3810 PF12725.7 OWF42461.1 - 0.71 9.2 4.7 0.33 10.3 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF4220 PF13968.6 OWF42461.1 - 0.72 9.2 7.4 2.3 7.5 7.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) DUF5367 PF17329.2 OWF42461.1 - 1.2 9.3 7.4 1.6 8.9 3.4 2.5 1 1 2 3 3 3 0 Family of unknown function (DUF5367) DUF1722 PF08349.11 OWF42462.1 - 0.02 15.1 1.9 0.02 15.1 1.9 5.8 2 2 4 6 6 6 0 Protein of unknown function (DUF1722) T4SS PF07996.11 OWF42463.1 - 0.055 13.9 0.7 0.19 12.1 0.3 1.9 1 1 1 2 2 2 0 Type IV secretion system proteins Baculo_PEP_C PF04513.12 OWF42464.1 - 0.084 12.9 5.1 0.16 12.0 5.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus T2SSM PF04612.12 OWF42464.1 - 0.097 12.7 1.5 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M LIF_OSM PF01291.17 OWF42464.1 - 0.1 12.7 1.3 0.18 11.9 0.8 1.7 2 0 0 2 2 2 0 LIF / OSM family FliD_N PF02465.18 OWF42464.1 - 0.12 13.1 9.7 0.037 14.7 5.1 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FPN1 PF06963.12 OWF42464.1 - 0.13 10.8 0.1 0.25 9.9 0.1 1.4 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4407 PF14362.6 OWF42464.1 - 0.99 8.7 13.8 0.038 13.3 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COG2 PF06148.11 OWF42464.1 - 4.2 7.5 11.1 0.12 12.5 1.8 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 OWF42464.1 - 4.5 6.4 11.0 0.15 11.3 1.5 2.3 2 0 0 2 2 2 0 TMPIT-like protein MMR_HSR1 PF01926.23 OWF42465.1 - 5.5e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF42465.1 - 7.9e-05 22.6 0.1 0.0016 18.4 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OWF42465.1 - 0.00017 22.0 0.0 0.0004 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 OWF42465.1 - 0.0008 18.6 0.0 0.0023 17.1 0.0 1.7 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 OWF42465.1 - 0.0011 18.5 0.1 0.003 17.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 OWF42465.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF42465.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF42465.1 - 0.0083 16.6 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 OWF42465.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 OWF42465.1 - 0.033 14.6 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AIG1 PF04548.16 OWF42465.1 - 0.04 13.2 0.1 0.098 12.0 0.1 1.6 1 0 0 1 1 1 0 AIG1 family AAA_23 PF13476.6 OWF42465.1 - 0.048 14.2 0.2 0.1 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OWF42465.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OWF42465.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 OWF42465.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin Sulfatase PF00884.23 OWF42465.1 - 0.13 11.6 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Sulfatase Roc PF08477.13 OWF42465.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 OWF42465.1 - 0.26 11.3 1.1 0.66 10.0 0.2 2.1 1 1 1 2 2 2 0 Helicase HerA, central domain Lectin_C PF00059.21 OWF42466.1 - 5.4e-12 46.4 3.9 9.3e-12 45.6 0.4 2.3 2 1 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 OWF42466.1 - 7.8e-10 38.6 3.5 0.00029 20.7 0.3 2.7 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.6 OWF42466.1 - 0.041 13.8 2.4 0.25 11.3 0.2 2.8 2 0 0 2 2 2 0 PAN domain MANEC PF07502.14 OWF42466.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.6 3 0 0 3 3 3 0 MANEC domain Arm PF00514.23 OWF42467.1 - 9.9e-05 22.2 7.9 1 9.5 0.1 6.9 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 OWF42467.1 - 0.034 14.2 9.5 0.95 9.5 0.0 5.6 6 1 1 7 7 7 0 Spinocerebellar ataxia type 10 protein domain Lectin_C PF00059.21 OWF42468.1 - 9.6e-10 39.2 0.1 1.8e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain Serpentine_r_xa PF03383.15 OWF42468.1 - 0.12 12.4 1.1 0.19 11.7 0.9 1.4 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa SGL PF08450.12 OWF42469.1 - 1.5e-62 211.4 0.1 1.8e-62 211.1 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF42469.1 - 0.003 17.6 3.8 1.1 9.7 0.2 3.3 4 0 0 4 4 4 2 Two component regulator propeller DUF839 PF05787.13 OWF42469.1 - 0.031 13.5 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) zf-DNL PF05180.12 OWF42470.1 - 0.072 13.0 17.9 1.4e+02 2.5 0.1 11.5 3 1 2 5 5 5 0 DNL zinc finger Lyase_1 PF00206.20 OWF42471.1 - 5.3e-26 91.7 0.0 8.1e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OWF42471.1 - 4.7e-12 46.3 0.0 1.3e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Glycos_transf_2 PF00535.26 OWF42472.1 - 3.5e-30 105.0 0.0 5.8e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF42472.1 - 1.1e-22 80.7 1.3 1.7e-22 80.0 1.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 OWF42472.1 - 4.5e-08 32.6 0.1 1.1e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 OWF42472.1 - 0.0012 19.5 0.1 0.015 16.0 0.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 OWF42472.1 - 0.052 13.0 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF2911 PF11138.8 OWF42472.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Antifungal_prot PF11402.8 OWF42472.1 - 0.19 12.0 1.9 0.22 11.8 0.3 1.9 2 0 0 2 2 2 0 Antifungal protein Pro-NT_NN PF07421.11 OWF42473.1 - 0.046 14.0 2.4 0.95 9.7 1.1 2.4 1 1 1 2 2 2 0 Neurotensin/neuromedin N precursor CALM_bind PF16025.5 OWF42473.1 - 3.4 8.2 11.8 41 4.7 11.8 2.1 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding CALM_bind PF16025.5 OWF42475.1 - 0.96 10.0 9.5 0.93 10.0 8.8 1.4 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding LRR_8 PF13855.6 OWF42476.1 - 5.4e-228 737.1 324.3 1.2e-15 57.0 5.1 19.1 2 1 24 26 26 26 26 Leucine rich repeat LRR_5 PF13306.6 OWF42476.1 - 3.7e-83 275.9 43.9 2.3e-12 47.0 0.1 10.0 1 1 11 13 13 13 13 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF42476.1 - 1.7e-80 263.4 195.1 1.6e-06 28.4 1.4 21.3 16 5 2 21 21 21 18 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF42476.1 - 5.6e-32 110.6 89.0 6.8e-06 25.7 5.0 12.1 3 3 9 14 14 14 13 Leucine-rich repeat 7tm_1 PF00001.21 OWF42476.1 - 2.7e-24 85.9 22.4 4.4e-24 85.2 22.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF42476.1 - 0.026 13.8 13.1 0.052 12.8 13.1 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw LRR_1 PF00560.33 OWF42476.1 - 0.058 14.0 158.7 0.35 11.6 0.2 31.1 35 3 0 35 35 34 0 Leucine Rich Repeat DUF1647 PF07801.11 OWF42476.1 - 0.12 12.2 16.9 0.41 10.4 0.4 7.2 4 2 5 10 10 10 0 Protein of unknown function (DUF1647) DUF4134 PF13572.6 OWF42476.1 - 1.2 9.4 6.8 55 4.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Suppressor_P21 PF11479.8 OWF42476.1 - 2.6 8.3 15.4 30 4.9 0.2 6.5 6 0 0 6 6 6 0 RNA silencing suppressor P21 C-terminal domain DUF999 PF06198.11 OWF42476.1 - 5.1 7.1 8.3 38 4.2 0.0 5.3 5 1 0 5 5 5 0 Protein of unknown function (DUF999) zf-met PF12874.7 OWF42477.1 - 3.1e-07 30.6 0.4 3.1e-07 30.6 0.4 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF42477.1 - 0.0025 18.1 10.8 0.12 12.7 0.2 4.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 OWF42477.1 - 1.4 8.7 15.6 1.6 8.6 0.1 4.5 4 0 0 4 4 4 0 U1 zinc finger CUT PF02376.15 OWF42478.1 - 1.6e-13 50.6 0.2 5.7e-13 48.8 0.1 2.1 2 1 0 2 2 2 1 CUT domain Homeodomain PF00046.29 OWF42478.1 - 5.3e-13 48.6 0.0 1.4e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF42478.1 - 0.013 15.4 0.1 0.045 13.7 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain Reprolysin PF01421.19 OWF42480.1 - 6.4e-40 137.2 0.8 6.4e-40 137.2 0.8 1.9 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 OWF42480.1 - 3.9e-26 91.9 3.0 8.3e-26 90.9 3.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.12 OWF42480.1 - 1.7e-24 86.4 5.6 1.7e-24 86.4 5.6 3.9 3 1 0 3 3 2 1 ADAM cysteine-rich Disintegrin PF00200.23 OWF42480.1 - 6.2e-18 65.4 28.3 6.2e-18 65.4 28.3 3.9 4 0 0 4 4 1 1 Disintegrin Reprolysin_5 PF13688.6 OWF42480.1 - 9.6e-12 45.5 0.2 3e-11 43.9 0.2 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF42480.1 - 1e-06 29.3 0.0 2.9e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF42480.1 - 7.7e-06 25.9 0.1 2.7e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF42480.1 - 9.5e-06 25.4 1.8 1.4e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF42480.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.13 OWF42480.1 - 0.056 13.4 0.4 0.18 11.7 0.4 1.8 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A PRIMA1 PF16101.5 OWF42480.1 - 0.62 10.1 0.0 0.62 10.1 0.0 2.9 3 0 0 3 3 2 0 Proline-rich membrane anchor 1 AAT PF03417.16 OWF42481.1 - 5.2e-07 29.6 0.0 2.1e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Peptidase_C69 PF03577.15 OWF42481.1 - 2.2e-05 23.6 0.3 7.2e-05 21.9 0.3 1.7 1 1 0 1 1 1 1 Peptidase family C69 C1q PF00386.21 OWF42482.1 - 5.7e-24 84.8 0.0 1.3e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF42482.1 - 1.9e-05 24.6 0.1 4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 BclA C-terminal domain TBCA PF02970.16 OWF42482.1 - 0.04 14.2 2.6 0.1 12.9 2.6 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A NHL PF01436.21 OWF42483.1 - 9.2e-08 31.8 2.5 0.052 13.6 0.0 4.2 4 0 0 4 4 4 2 NHL repeat zf-RING_5 PF14634.6 OWF42483.1 - 2.5e-05 24.1 10.9 2.5e-05 24.1 10.9 3.6 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF42483.1 - 5.2e-05 23.5 13.2 5.2e-05 23.5 13.2 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF42483.1 - 5.3e-05 23.1 13.1 5.3e-05 23.1 13.1 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF42483.1 - 6.5e-05 22.7 13.3 6.5e-05 22.7 13.3 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF42483.1 - 0.0001 22.0 0.1 0.0023 17.6 0.1 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4_3 PF13920.6 OWF42483.1 - 0.00047 20.0 9.6 0.00047 20.0 9.6 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF42483.1 - 0.00066 19.8 14.8 0.00066 19.8 14.8 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF42483.1 - 0.004 17.0 14.5 0.004 17.0 14.5 3.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4906 PF16249.5 OWF42483.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4906) PspA_IM30 PF04012.12 OWF42483.1 - 0.021 14.4 1.3 0.045 13.3 1.3 1.4 1 0 0 1 1 1 0 PspA/IM30 family DUF948 PF06103.11 OWF42483.1 - 0.042 14.1 0.4 0.12 12.6 0.4 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Mer2 PF09074.10 OWF42483.1 - 0.068 13.0 4.8 0.14 11.9 4.8 1.5 1 0 0 1 1 1 0 Mer2 Baculo_PEP_C PF04513.12 OWF42483.1 - 0.095 12.7 0.3 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zinc_ribbon_10 PF10058.9 OWF42483.1 - 0.54 10.0 8.1 0.91 9.3 0.7 3.8 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein ALMT PF11744.8 OWF42483.1 - 8.3 5.1 6.2 20 3.8 6.1 1.6 1 1 0 1 1 1 0 Aluminium activated malate transporter CUB PF00431.20 OWF42484.1 - 2.8e-05 24.4 0.1 5.5e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 CUB domain Cadherin_C_2 PF16492.5 OWF42484.1 - 0.005 17.6 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal CUB_2 PF02408.20 OWF42484.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 CUB-like domain UPF0193 PF05250.11 OWF42485.1 - 0.058 13.2 0.1 0.076 12.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) SpoIID PF08486.10 OWF42485.1 - 0.072 13.6 0.4 0.12 12.9 0.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein EIIBC-GUT_N PF03612.14 OWF42485.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Alkyl_sulf_dimr PF14863.6 OWF42486.1 - 2.8e-36 125.0 0.0 4.2e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 OWF42486.1 - 1.3e-15 58.0 0.3 3.5e-15 56.6 0.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OWF42486.1 - 2e-06 27.5 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Alkyl_sulf_C PF14864.6 OWF42486.1 - 3.3e-06 27.4 0.7 6.5e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal zf-H2C2_2 PF13465.6 OWF42487.1 - 3.8e-43 144.0 55.5 2.7e-08 33.9 0.3 9.3 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 OWF42487.1 - 2.2e-33 112.9 61.7 0.00013 22.2 2.5 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF42487.1 - 6.6e-26 88.8 56.0 0.0016 19.1 1.5 8.7 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 OWF42487.1 - 9.8e-11 41.7 49.0 0.005 17.2 0.3 8.2 8 0 0 8 8 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF42487.1 - 1.1e-09 38.3 41.0 0.0023 18.1 0.9 8.5 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF42487.1 - 1.4e-06 28.2 53.4 0.0076 16.2 0.4 7.8 8 1 0 8 8 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF42487.1 - 1.5e-06 27.8 6.1 0.00022 20.9 2.2 6.5 8 0 0 8 8 8 2 C2H2-type zinc-finger domain DUF3268 PF11672.8 OWF42487.1 - 0.0094 16.3 12.6 2.6 8.4 0.1 4.2 4 0 0 4 4 4 3 zinc-finger-containing domain zf-Di19 PF05605.12 OWF42487.1 - 0.02 15.2 2.2 0.02 15.2 2.2 6.1 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 OWF42487.1 - 0.073 13.8 25.3 4.3 8.2 1.4 4.6 3 1 1 4 4 4 0 zinc-ribbon family BolA PF01722.18 OWF42487.1 - 0.84 10.0 5.5 27 5.1 0.5 4.4 3 1 0 3 3 3 0 BolA-like protein Hydrolase_4 PF12146.8 OWF42488.1 - 7e-80 267.7 0.0 8.4e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OWF42488.1 - 6.9e-17 61.9 0.2 6.3e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF42488.1 - 6.7e-12 46.5 0.0 9.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OWF42488.1 - 2.4e-07 30.4 0.1 0.0051 16.3 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 OWF42488.1 - 1.2e-06 28.3 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 OWF42488.1 - 7.2e-06 25.7 0.0 0.079 12.5 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Lipase_3 PF01764.25 OWF42488.1 - 9e-06 25.6 0.0 6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Peptidase_S15 PF02129.18 OWF42488.1 - 4.3e-05 23.3 0.0 0.0079 15.8 0.0 2.4 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 OWF42488.1 - 8.2e-05 22.4 0.1 0.00014 21.7 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 OWF42488.1 - 0.00033 19.6 0.1 0.00051 19.0 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme LIP PF03583.14 OWF42488.1 - 0.00039 19.8 0.0 0.0044 16.4 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase DUF2920 PF11144.8 OWF42488.1 - 0.00048 19.4 0.3 0.034 13.3 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2920) LIDHydrolase PF10230.9 OWF42488.1 - 0.00057 19.5 0.2 0.0073 15.9 0.0 2.2 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 OWF42488.1 - 0.0018 18.1 0.3 0.15 11.8 0.1 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 OWF42488.1 - 0.002 16.7 0.0 0.11 11.0 0.0 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.20 OWF42488.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.13 OWF42488.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase Esterase_phd PF10503.9 OWF42488.1 - 0.075 12.5 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 OWF42488.1 - 0.085 12.5 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Palm_thioest PF02089.15 OWF42488.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2974 PF11187.8 OWF42488.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LCAT PF02450.15 OWF42488.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 OWF42488.1 - 0.16 11.8 0.1 1.1 9.0 0.0 2.2 3 0 0 3 3 2 0 Alpha/beta hydrolase family ATP-synt PF00231.19 OWF42490.1 - 5.2e-77 259.3 1.8 5.9e-77 259.1 1.8 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S27 PF01599.19 OWF42490.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a Sortilin-Vps10 PF15902.5 OWF42491.1 - 1.1e-57 195.8 0.3 1.7e-57 195.3 0.3 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OWF42491.1 - 6.5e-37 127.5 3.8 1e-36 126.9 3.8 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 OWF42491.1 - 0.00094 18.8 4.9 4.7 7.6 0.1 3.8 3 0 0 3 3 3 3 BNR/Asp-box repeat LRR19-TM PF15176.6 OWF42491.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain LtrA PF06772.11 OWF42491.1 - 0.12 11.6 0.2 0.17 11.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Sortilin-Vps10 PF15902.5 OWF42492.1 - 4.9e-12 45.4 0.0 8.9e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 OWF42492.1 - 0.0027 17.4 0.2 4.1 7.8 0.0 2.7 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_6 PF15899.5 OWF42492.1 - 0.017 15.2 0.6 0.14 12.3 0.3 2.5 2 0 0 2 2 2 0 BNR-Asp box repeat WD40 PF00400.32 OWF42493.1 - 1.4e-40 136.5 23.6 2.4e-06 28.2 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF42493.1 - 2.3e-08 34.2 0.7 0.28 11.5 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF42493.1 - 0.0042 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain COesterase PF00135.28 OWF42494.1 - 1.1e-279 928.5 0.0 6.2e-141 470.8 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF42494.1 - 2.9e-14 53.5 2.5 9.3e-06 25.6 0.7 3.7 2 2 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF42494.1 - 8.6e-09 35.2 0.3 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OWF42494.1 - 0.005 15.7 0.8 0.58 9.0 0.0 2.9 2 2 0 2 2 2 2 Steryl acetyl hydrolase COesterase PF00135.28 OWF42495.1 - 8.8e-126 420.8 0.0 1.1e-125 420.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF42495.1 - 8.5e-10 38.8 0.2 3.3e-09 36.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF42495.1 - 0.0046 16.5 0.1 0.0074 15.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OWF42495.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase JHD PF17811.1 OWF42496.1 - 3.8e-31 107.7 0.1 3.8e-31 107.7 0.1 2.7 3 0 0 3 3 3 1 Jumonji helical domain JmjC PF02373.22 OWF42496.1 - 1e-09 38.8 0.7 1e-09 38.8 0.7 3.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OWF42496.1 - 2.3e-08 34.1 0.4 2.3e-08 34.1 0.4 2.9 2 1 0 2 2 2 1 Cupin-like domain SpoIIP PF07454.11 OWF42496.1 - 0.058 12.9 14.7 0.026 14.0 9.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RRM_1 PF00076.22 OWF42497.1 - 1.1e-37 127.7 0.3 8.1e-19 67.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF42497.1 - 9.4e-11 41.7 0.1 0.0006 19.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OWF42497.1 - 0.0089 16.1 0.2 0.95 9.5 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 OWF42497.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_IV PF11411.8 OWF42497.1 - 0.19 11.9 4.2 12 6.1 0.0 3.4 3 0 0 3 3 3 0 DNA ligase IV GlcNAc_2-epim PF07221.11 OWF42498.1 - 8.6e-47 160.0 0.3 1.1e-46 159.6 0.3 1.1 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF3052 PF11253.8 OWF42498.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Peptidase_M4_C PF02868.15 OWF42498.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain LEM PF03020.15 OWF42499.1 - 2.2e-19 68.7 1.5 2.3e-17 62.3 0.7 2.6 2 0 0 2 2 2 2 LEM domain Thymopoietin PF08198.11 OWF42499.1 - 1.1e-13 50.5 0.5 2.1e-13 49.6 0.5 1.5 1 0 0 1 1 1 1 Thymopoietin protein SAP PF02037.27 OWF42499.1 - 0.012 15.3 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 SAP domain SPATA48 PF15073.6 OWF42499.1 - 0.029 14.7 7.0 0.12 12.7 0.3 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 HeH PF12949.7 OWF42499.1 - 0.085 12.6 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 HeH/LEM domain Ish1 PF10281.9 OWF42499.1 - 0.12 12.8 0.1 4.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Exo_endo_phos PF03372.23 OWF42500.1 - 3.2e-18 66.1 0.1 5.3e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OWF42500.1 - 7e-13 48.5 4.4 1.8e-12 47.1 4.4 1.8 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OWF42500.1 - 0.00045 20.1 0.8 0.022 14.6 0.0 3.3 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase DLIC PF05783.11 OWF42500.1 - 9.1 5.0 10.4 47 2.6 10.2 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DUF4064 PF13273.6 OWF42501.1 - 0.038 14.3 0.1 0.076 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Adeno_E3_CR2 PF02439.15 OWF42501.1 - 0.04 13.7 5.1 0.073 12.8 5.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UCH PF00443.29 OWF42503.1 - 3.1e-72 243.2 0.0 5.2e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF42503.1 - 5.1e-16 59.2 1.1 6e-07 29.4 0.1 4.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase CS PF04969.16 OWF42503.1 - 2.4e-10 41.3 3.6 6.3e-10 39.9 1.9 2.4 2 0 0 2 2 2 1 CS domain zf-MYND PF01753.18 OWF42503.1 - 8.7e-08 32.1 17.6 8.7e-08 32.1 17.6 2.6 3 0 0 3 3 3 1 MYND finger USP7_C2 PF14533.6 OWF42503.1 - 4.7e-05 23.2 0.0 9.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf_Hakai PF18408.1 OWF42504.1 - 6.8e-17 60.9 4.5 1.3e-16 60.0 4.5 1.5 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain Prok-RING_4 PF14447.6 OWF42504.1 - 0.00051 19.8 3.3 0.00051 19.8 3.3 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OWF42504.1 - 0.002 17.9 13.6 0.0062 16.4 13.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF42504.1 - 0.0057 16.5 13.3 0.022 14.6 13.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF42504.1 - 0.038 13.9 12.4 0.11 12.4 12.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF42504.1 - 0.05 13.6 13.7 0.1 12.6 13.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-LITAF-like PF10601.9 OWF42504.1 - 0.14 12.4 6.0 0.28 11.5 6.0 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain zf-RING_2 PF13639.6 OWF42504.1 - 0.2 12.0 14.7 0.45 10.9 14.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 OWF42504.1 - 0.54 10.3 9.5 1.5 8.9 9.5 1.8 1 1 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 OWF42504.1 - 1.9 8.5 7.9 4.4 7.4 7.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 OWF42504.1 - 5.7 7.0 9.6 10 6.2 9.6 1.3 1 0 0 1 1 1 0 zinc-ribbons UPF0239 PF06783.11 OWF42505.1 - 6.3e-21 74.4 0.2 7.7e-21 74.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) OATP PF03137.20 OWF42505.1 - 0.026 12.8 0.0 0.029 12.7 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MscL PF01741.18 OWF42505.1 - 0.063 13.6 0.1 0.072 13.4 0.1 1.2 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL G0-G1_switch_2 PF15103.6 OWF42505.1 - 0.088 13.2 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF5331 PF17265.2 OWF42505.1 - 0.091 12.5 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5331) GTSE1_N PF15259.6 OWF42506.1 - 2.5e-18 66.6 1.8 2.5e-18 66.6 1.8 2.7 3 1 0 3 3 3 1 G-2 and S-phase expressed 1 Gelsolin PF00626.22 OWF42507.1 - 4.3e-39 132.3 0.1 4e-15 55.5 0.1 3.2 3 0 0 3 3 3 3 Gelsolin repeat CENP-B_dimeris PF09026.10 OWF42507.1 - 0.84 10.1 7.9 2 8.9 7.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Gelsolin PF00626.22 OWF42508.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Varsurf_PPLC PF03490.13 OWF42509.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C BNR_assoc_N PF14873.6 OWF42509.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase Gelsolin PF00626.22 OWF42510.1 - 3.9e-43 145.2 0.1 2.4e-15 56.2 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat GP67 PF17634.2 OWF42510.1 - 0.043 14.2 2.3 0.085 13.3 2.3 1.4 1 0 0 1 1 1 0 Gene product 67 Rhabdo_ncap PF00945.18 OWF42510.1 - 0.55 9.0 2.9 0.84 8.4 2.9 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Gelsolin PF00626.22 OWF42511.1 - 4.7e-28 96.9 0.1 4.6e-14 52.1 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat XPC-binding PF09280.11 OWF42512.1 - 8.1e-16 57.5 57.5 11 5.8 0.3 19.1 1 1 26 27 27 27 27 XPC-binding domain zf-RING_UBOX PF13445.6 OWF42513.1 - 1.9e-12 47.0 6.6 3.8e-12 46.0 4.5 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF42513.1 - 4.4e-09 36.1 7.3 4.4e-09 36.1 7.3 3.5 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF42513.1 - 1.8e-08 34.0 1.0 0.0011 18.9 0.0 3.5 3 0 0 3 3 3 2 NHL repeat zf-C3HC4_4 PF15227.6 OWF42513.1 - 2.1e-08 34.2 9.0 2.1e-08 34.2 9.0 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF42513.1 - 2e-07 31.2 6.2 2e-07 31.2 6.2 3.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF42513.1 - 2.8e-07 30.2 2.5 2.8e-07 30.2 2.5 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF42513.1 - 1.4e-06 28.1 6.1 1.4e-06 28.1 6.1 3.6 5 0 0 5 5 5 1 zinc-RING finger domain SBBP PF06739.11 OWF42513.1 - 9.9e-06 25.5 0.7 2.3e-05 24.3 0.7 1.6 1 0 0 1 1 1 1 Beta-propeller repeat zf-C3HC4_3 PF13920.6 OWF42513.1 - 1.2e-05 25.0 5.6 1.2e-05 25.0 5.6 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF42513.1 - 0.0017 18.1 5.0 0.0017 18.1 5.0 3.3 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 Phytase-like PF13449.6 OWF42513.1 - 0.034 14.1 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Esterase-like activity of phytase SGL PF08450.12 OWF42513.1 - 0.041 13.5 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Rsa3 PF14615.6 OWF42513.1 - 0.15 11.6 0.1 0.41 10.3 0.1 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 IKKbetaNEMObind PF12179.8 OWF42513.1 - 0.25 11.4 1.7 0.53 10.4 0.6 2.2 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Gelsolin PF00626.22 OWF42514.1 - 7.8e-27 93.0 1.4 3.4e-14 52.5 0.1 3.4 3 0 0 3 3 3 2 Gelsolin repeat PAC4 PF16093.5 OWF42514.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 RabGAP-TBC PF00566.18 OWF42515.1 - 1.4e-36 126.2 0.1 3.2e-36 125.0 0.1 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4682 PF15733.5 OWF42515.1 - 6.3e-13 49.4 1.7 2e-12 47.8 1.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) LPP PF04728.13 OWF42515.1 - 1.5 9.2 4.0 1.6 9.1 0.4 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper 7TM_GPCR_Srw PF10324.9 OWF42517.1 - 3.8e-20 72.4 16.2 5e-20 72.0 16.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF42517.1 - 3e-17 62.8 12.5 5.9e-17 61.9 12.5 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF42517.1 - 0.00047 19.9 5.4 0.00047 19.9 5.4 2.9 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx GLTT PF01744.20 OWF42520.1 - 0.08 12.7 0.1 22 4.9 0.0 2.8 2 0 0 2 2 2 0 GLTT repeat (6 copies) Baculo_ME53 PF06061.11 OWF42520.1 - 1.8 7.7 9.9 1.9 7.7 1.2 3.2 1 1 2 3 3 3 0 Baculoviridae ME53 Baculo_ME53 PF06061.11 OWF42521.1 - 1.4 8.1 25.1 3.3 6.9 0.4 6.6 1 1 5 7 7 7 0 Baculoviridae ME53 Baculo_ME53 PF06061.11 OWF42522.1 - 0.34 10.1 14.0 6.9 5.8 0.3 5.1 1 1 5 7 7 7 0 Baculoviridae ME53 Aldolase PF01081.19 OWF42523.1 - 0.0012 18.3 2.1 0.91 8.9 0.1 3.3 2 1 2 4 4 4 2 KDPG and KHG aldolase Tobravirus_2B PF05271.11 OWF42523.1 - 0.82 9.6 2.8 4.8 7.1 0.2 3.0 2 2 0 2 2 2 0 Tobravirus 2B protein GFRP PF06399.13 OWF42524.1 - 0.0027 17.6 25.3 9.3 6.2 0.8 8.4 1 1 7 9 9 9 4 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF2118 PF09891.9 OWF42524.1 - 0.73 9.8 21.6 10 6.1 0.4 3.9 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) GFRP PF06399.13 OWF42525.1 - 0.43 10.5 24.1 57 3.7 0.6 8.5 1 1 7 8 8 8 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) SICA_C PF12879.7 OWF42525.1 - 3.2 7.8 7.7 51 3.9 0.1 4.4 1 1 4 5 5 5 0 SICA C-terminal inner membrane domain DUF3400 PF11880.8 OWF42526.1 - 0.012 15.1 2.9 56 3.4 0.0 5.5 6 2 1 7 7 7 0 Domain of unknown function (DUF3400) AIM24 PF01987.17 OWF42526.1 - 0.21 11.4 1.4 2 8.1 0.4 2.7 1 1 1 2 2 2 0 Mitochondrial biogenesis AIM24 DUF5417 PF17438.2 OWF42528.1 - 4.4e-08 33.3 0.0 10 6.5 0.0 7.0 1 1 5 8 8 8 1 Family of unknown function (DUF5417) JAB PF01398.21 OWF42528.1 - 0.82 9.7 24.3 11 6.0 0.2 9.0 5 3 6 11 11 11 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TGF_beta PF00019.20 OWF42528.1 - 4.4 8.3 13.8 46 5.0 0.1 7.5 1 1 3 4 4 4 0 Transforming growth factor beta like domain PRELI PF04707.14 OWF42530.1 - 1.9e-30 105.8 0.1 1.9e-30 105.8 0.1 1.3 2 0 0 2 2 2 1 PRELI-like family Mannitol_dh_C PF08125.13 OWF42530.1 - 0.055 12.9 0.0 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain HA2 PF04408.23 OWF42530.1 - 0.18 12.1 0.0 0.41 11.0 0.0 1.6 1 1 0 1 1 1 0 Helicase associated domain (HA2) DSPc PF00782.20 OWF42531.1 - 2e-19 69.7 0.1 5.3e-19 68.3 0.1 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain UPF0302 PF08864.10 OWF42531.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 UPF0302 domain DUF3678 PF12435.8 OWF42531.1 - 6.2 6.3 8.7 3.2 7.2 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) RNA_pol_Rpb2_6 PF00562.28 OWF42532.1 - 5.6e-127 424.0 0.0 7.1e-127 423.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 OWF42532.1 - 1.2e-35 121.8 0.2 2.6e-35 120.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 OWF42532.1 - 6.1e-28 96.9 1.1 1.3e-27 95.8 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OWF42532.1 - 1.7e-21 76.2 0.0 4.1e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OWF42532.1 - 2.8e-12 47.0 1.6 8e-12 45.5 1.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Mab-21 PF03281.14 OWF42533.1 - 8.9e-27 94.1 4.3 1.4e-26 93.5 4.3 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF42533.1 - 0.0036 17.6 0.0 1 9.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF155 PF02582.14 OWF42535.1 - 5.1e-42 144.0 0.3 9.2e-42 143.1 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cytochrome_cB PF11783.8 OWF42535.1 - 0.099 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c bacterial tRNA-synt_2 PF00152.20 OWF42536.1 - 2.8e-92 309.2 0.0 3.6e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OWF42536.1 - 4.2e-10 39.5 0.1 9.6e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 OWF42536.1 - 1.2e-05 25.5 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 OWF42536.1 - 0.014 14.9 0.0 0.28 10.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Mab-21 PF03281.14 OWF42537.1 - 2.7e-21 76.1 5.7 4.4e-21 75.5 5.7 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_14 PF13428.6 OWF42537.1 - 0.016 16.0 0.1 0.24 12.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NTP_transf_2 PF01909.23 OWF42537.1 - 0.038 14.3 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PIP49_C PF12260.8 OWF42538.1 - 9.1e-07 28.7 0.2 5.8e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 RNA_pol_L_2 PF13656.6 OWF42539.1 - 4.7e-27 93.6 0.1 6.7e-27 93.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OWF42539.1 - 2.7e-08 33.1 0.1 6.3e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GPS2_interact PF15784.5 OWF42540.1 - 3.2e-27 94.8 12.4 3.2e-27 94.8 12.4 3.4 3 0 0 3 3 3 1 G-protein pathway suppressor 2-interacting domain Myb_DNA-binding PF00249.31 OWF42540.1 - 5.4e-19 68.1 1.1 2.1e-11 43.8 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF42540.1 - 7.8e-06 26.0 7.4 0.016 15.4 0.6 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain SH2_2 PF14633.6 OWF42541.1 - 2e-82 275.8 1.1 4.1e-82 274.8 1.1 1.6 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 OWF42541.1 - 2.1e-41 140.5 0.1 3.9e-41 139.6 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 OWF42541.1 - 2.9e-26 92.0 0.0 1.6e-25 89.7 0.0 2.4 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 OWF42541.1 - 1.2e-23 83.7 2.7 3.3e-23 82.3 2.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 OWF42541.1 - 6e-11 42.8 21.3 6e-11 42.8 21.3 6.0 5 1 1 6 6 4 1 Acidic N-terminal SPT6 S1 PF00575.23 OWF42541.1 - 1.6e-10 41.1 0.1 3.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 OWF42541.1 - 1.4e-09 37.9 0.0 4.1e-05 23.6 0.0 2.9 2 0 0 2 2 2 2 SH2 domain Tex_N PF09371.10 OWF42541.1 - 2.2e-09 37.3 1.1 0.00019 21.2 0.9 3.6 2 1 0 2 2 2 2 Tex-like protein N-terminal domain HHH_3 PF12836.7 OWF42541.1 - 1.4e-07 31.6 0.0 5.8e-07 29.7 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 OWF42541.1 - 1.6e-05 25.7 2.8 2.2e-05 25.3 0.3 2.8 2 0 0 2 2 1 1 HHH domain BaffR-Tall_bind PF09256.10 OWF42541.1 - 0.04 13.7 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Acyl-CoA_dh_1 PF00441.24 OWF42542.1 - 2.2e-28 99.4 0.2 7.9e-28 97.6 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OWF42542.1 - 6e-16 58.4 0.1 1.1e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF42542.1 - 1.2e-09 38.5 0.4 4.8e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 OWF42542.1 - 2.6e-06 27.5 0.0 5.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Sulfotransfer_3 PF13469.6 OWF42543.1 - 3e-51 174.9 0.0 7.2e-51 173.6 0.0 1.7 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF42543.1 - 2e-07 30.7 0.1 1.1e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Pkinase PF00069.25 OWF42544.1 - 8.1e-64 215.5 0.0 1.9e-63 214.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42544.1 - 1e-32 113.4 0.0 7.8e-31 107.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OWF42544.1 - 7.3e-08 32.1 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF42544.1 - 0.00028 19.8 0.2 0.0026 16.6 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OWF42544.1 - 0.11 12.4 0.6 1.5 8.7 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family SRCR PF00530.18 OWF42546.1 - 1.6e-59 198.6 12.0 3.2e-27 95.0 0.8 6.3 4 1 2 6 6 6 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF42546.1 - 3.8e-05 24.2 1.4 0.0059 17.1 0.2 5.4 5 0 0 5 5 5 2 Scavenger receptor cysteine-rich domain Ank_2 PF12796.7 OWF42547.1 - 4.9e-08 33.4 0.1 3.4e-05 24.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF42547.1 - 0.00043 20.5 0.7 7.5 7.5 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat NACHT PF05729.12 OWF42547.1 - 0.0015 18.5 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 OWF42547.1 - 0.0036 17.8 0.0 1.4 9.5 0.0 3.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) DUF2075 PF09848.9 OWF42547.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OWF42547.1 - 0.037 14.4 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 OWF42547.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Hormone_4 PF00220.17 OWF42547.1 - 0.1 12.6 1.5 0.44 10.6 1.5 2.1 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Ank_2 PF12796.7 OWF42548.1 - 4.2e-11 43.3 2.2 3.1e-06 27.7 2.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF42548.1 - 6.4e-08 32.3 0.2 0.86 10.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF42548.1 - 6.6e-07 29.5 0.2 0.0064 16.8 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF42548.1 - 0.0092 16.6 1.3 7.9 7.2 0.2 3.8 1 1 4 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF42548.1 - 0.016 15.7 0.1 18 6.0 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat SRCR PF00530.18 OWF42549.1 - 8.2e-104 340.7 41.5 2.4e-26 92.2 1.2 6.3 6 1 1 7 7 7 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF42549.1 - 2e-18 66.7 18.9 2.2e-06 28.1 0.2 6.0 6 0 0 6 6 6 4 Scavenger receptor cysteine-rich domain SIT PF15330.6 OWF42549.1 - 0.011 16.2 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Alpha_kinase PF02816.18 OWF42551.1 - 9.6e-27 94.3 0.0 1.2e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Ocular_alb PF02101.15 OWF42552.1 - 8.1e-37 127.1 12.3 1.1e-36 126.6 12.3 1.3 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.24 OWF42552.1 - 2.8e-08 33.3 11.1 2.8e-08 33.3 11.1 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) DNA_pol_B_N PF18094.1 OWF42553.1 - 8.4e-06 26.3 4.8 2.4 8.7 0.1 4.9 1 1 0 4 4 4 3 DNA polymerase beta N-terminal domain LolB PF03550.14 OWF42553.1 - 5e-05 23.4 1.5 5.6 7.0 0.1 5.4 1 1 6 7 7 7 2 Outer membrane lipoprotein LolB GTF2I PF02946.14 OWF42553.1 - 0.00037 20.5 5.8 10 6.3 0.0 7.9 1 1 7 11 11 11 1 GTF2I-like repeat Herpes_UL42 PF02282.16 OWF42553.1 - 0.17 11.7 24.1 5.5 6.9 0.8 6.4 1 1 4 6 6 6 0 DNA polymerase processivity factor (UL42) DUF4072 PF13284.6 OWF42554.1 - 6.4e-06 26.5 18.8 47 4.5 0.0 11.7 7 4 6 15 15 15 5 Domain of unknown function (DUF4072) DUF1242 PF06842.12 OWF42555.1 - 0.026 14.3 0.4 3.8 7.4 0.0 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1242) TMEM173 PF15009.6 OWF42555.1 - 2.1 7.4 5.1 11 5.1 4.0 2.2 1 1 0 1 1 1 0 Transmembrane protein 173 DUF1242 PF06842.12 OWF42556.1 - 5.1e-06 26.2 16.0 3.2 7.6 0.0 9.3 4 3 4 8 8 8 4 Protein of unknown function (DUF1242) Antimicrobial_1 PF08018.11 OWF42556.1 - 0.4 10.9 24.0 2.1e+02 2.2 0.1 10.8 12 0 0 12 12 12 0 Frog antimicrobial peptide TAFH PF07531.14 OWF42556.1 - 0.44 10.7 6.2 18 5.5 0.1 3.9 1 1 4 5 5 5 0 NHR1 homology to TAF Glyco_transf_10 PF00852.19 OWF42558.1 - 5e-35 120.8 0.3 5.5e-35 120.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Actin PF00022.19 OWF42559.1 - 7.2e-90 301.5 0.0 1.7e-58 198.2 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 OWF42559.1 - 1.1e-05 24.5 0.0 0.056 12.2 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OWF42559.1 - 0.0023 18.3 0.0 0.0093 16.4 0.0 2.0 2 1 0 2 2 2 1 Cell division protein FtsA Robl_LC7 PF03259.17 OWF42559.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain GLTP PF08718.11 OWF42560.1 - 1.1e-41 142.5 0.0 2.7e-41 141.3 0.0 1.7 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH PF00169.29 OWF42560.1 - 3.4e-12 46.8 0.1 7.6e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF42560.1 - 5.6e-08 33.1 0.1 5.6e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 OWF42560.1 - 0.0039 17.5 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain TNFR_c6 PF00020.18 OWF42561.1 - 0.00017 21.9 5.1 0.00017 21.9 5.1 3.6 5 0 0 5 5 5 2 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 OWF42561.1 - 0.81 9.5 17.9 0.57 10.0 3.9 3.6 2 1 1 3 3 3 0 Putative ephrin-receptor like zf-C2H2_4 PF13894.6 OWF42562.1 - 2.2e-05 24.9 3.9 0.044 14.6 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF42562.1 - 4.9e-05 23.6 5.2 0.024 15.1 2.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF42562.1 - 0.00083 19.1 1.2 0.00083 19.1 1.2 1.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 OWF42562.1 - 0.001 19.3 0.5 0.0015 18.7 0.5 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OWF42562.1 - 0.076 13.4 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OrsD PF12013.8 OWF42562.1 - 0.099 13.1 0.5 0.28 11.7 0.4 1.6 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D LPP PF04728.13 OWF42563.1 - 2.6e-10 40.5 7.5 0.08 13.3 0.5 5.0 1 1 3 4 4 4 3 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 OWF42563.1 - 2.8e-08 33.9 4.5 0.0003 20.8 1.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 OWF42563.1 - 1.3e-07 31.7 10.7 0.00036 20.5 3.4 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 OWF42563.1 - 2.6e-06 27.6 5.8 0.016 15.5 0.2 2.4 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 WEMBL PF05701.11 OWF42563.1 - 5.9e-06 25.3 2.9 8.6e-06 24.7 2.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light GAS PF13851.6 OWF42563.1 - 1.7e-05 24.3 3.1 0.00071 19.0 0.5 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding PI3K_P85_iSH2 PF16454.5 OWF42563.1 - 3.8e-05 23.4 0.1 0.00014 21.5 0.1 1.9 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 OWF42563.1 - 6.4e-05 22.0 5.1 0.00019 20.4 5.1 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.12 OWF42563.1 - 6.9e-05 22.9 7.8 0.00054 20.0 3.4 2.3 1 1 1 2 2 2 2 Laminin Domain II ADIP PF11559.8 OWF42563.1 - 0.00011 22.3 0.2 0.064 13.4 0.1 2.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 OWF42563.1 - 0.00011 22.6 4.8 0.17 12.4 0.6 2.4 1 1 1 2 2 2 2 Protein of unknown function DUF16 DUF4201 PF13870.6 OWF42563.1 - 0.00014 21.7 2.4 0.012 15.4 0.8 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 OWF42563.1 - 0.00014 22.2 2.0 0.59 10.6 0.4 2.7 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 OWF42563.1 - 0.00046 18.5 11.9 0.00069 17.9 2.0 2.6 2 1 1 3 3 3 2 Septation ring formation regulator, EzrA AIP3 PF03915.13 OWF42563.1 - 0.00052 19.2 3.4 0.00075 18.7 3.4 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Seryl_tRNA_N PF02403.22 OWF42563.1 - 0.00067 19.9 11.3 0.042 14.1 1.6 3.3 1 1 2 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Golgin_A5 PF09787.9 OWF42563.1 - 0.0007 19.2 2.0 0.01 15.3 0.3 2.2 1 1 1 2 2 2 1 Golgin subfamily A member 5 KASH_CCD PF14662.6 OWF42563.1 - 0.00083 19.2 3.2 0.002 18.0 2.3 1.9 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH COG7 PF10191.9 OWF42563.1 - 0.001 17.4 9.6 1.1 7.5 0.3 3.9 1 1 3 4 4 4 1 Golgi complex component 7 (COG7) ERM PF00769.19 OWF42563.1 - 0.0011 18.9 1.9 0.0011 18.9 1.9 1.4 2 0 0 2 2 1 1 Ezrin/radixin/moesin family IFT57 PF10498.9 OWF42563.1 - 0.0011 18.1 2.9 0.0025 16.9 2.8 1.6 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 YabA PF06156.13 OWF42563.1 - 0.0011 19.6 6.2 0.46 11.1 1.5 3.7 2 1 0 2 2 1 1 Initiation control protein YabA S6OS1 PF15676.5 OWF42563.1 - 0.0011 17.5 0.0 0.042 12.3 0.0 2.2 1 1 1 2 2 2 1 Six6 opposite strand transcript 1 family Fez1 PF06818.15 OWF42563.1 - 0.0013 19.2 4.7 0.028 14.9 4.6 2.4 1 1 0 1 1 1 1 Fez1 TMPIT PF07851.13 OWF42563.1 - 0.0014 18.0 1.8 0.15 11.3 1.0 2.2 1 1 1 2 2 2 1 TMPIT-like protein EMP24_GP25L PF01105.24 OWF42563.1 - 0.0015 18.5 1.8 0.39 10.6 1.8 2.7 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LapA_dom PF06305.11 OWF42563.1 - 0.0019 17.9 0.0 0.0058 16.4 0.0 1.9 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF2205 PF10224.9 OWF42563.1 - 0.002 18.1 5.9 3.2 7.8 0.3 4.1 1 1 3 4 4 4 0 Short coiled-coil protein Atg14 PF10186.9 OWF42563.1 - 0.0023 17.1 0.2 0.034 13.2 0.2 2.3 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 OWF42563.1 - 0.0031 17.7 0.7 0.0031 17.7 0.7 3.9 2 1 1 4 4 3 1 Haemolysin XhlA Filament PF00038.21 OWF42563.1 - 0.0033 17.0 1.1 0.27 10.8 0.2 2.2 1 1 1 2 2 2 1 Intermediate filament protein Sec34 PF04136.15 OWF42563.1 - 0.0036 17.2 2.8 0.52 10.2 0.2 3.2 1 1 1 3 3 3 1 Sec34-like family DUF2968 PF11180.8 OWF42563.1 - 0.0039 16.8 0.0 0.15 11.7 0.0 2.8 2 1 0 3 3 2 1 Protein of unknown function (DUF2968) CALCOCO1 PF07888.11 OWF42563.1 - 0.0042 16.0 5.6 0.023 13.6 5.6 1.9 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Tektin PF03148.14 OWF42563.1 - 0.0045 15.8 2.9 0.098 11.4 0.2 3.2 2 1 0 2 2 2 1 Tektin family Furin-like_2 PF15913.5 OWF42563.1 - 0.0052 16.9 4.0 0.0052 16.9 4.0 2.2 2 0 0 2 2 1 1 Furin-like repeat, cysteine-rich DUF4618 PF15397.6 OWF42563.1 - 0.0058 16.1 2.8 0.57 9.6 3.0 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) bZIP_1 PF00170.21 OWF42563.1 - 0.0061 16.6 8.1 7.1 6.8 0.2 4.4 1 1 3 4 4 4 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 OWF42563.1 - 0.0063 16.6 2.5 0.077 13.1 0.2 2.6 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 OWF42563.1 - 0.0072 15.7 3.0 0.013 14.9 3.0 1.3 1 0 0 1 1 1 1 Rabaptin-like protein ZapB PF06005.12 OWF42563.1 - 0.0082 16.6 6.1 1.6 9.3 0.3 4.1 2 1 1 3 3 2 0 Cell division protein ZapB Phage_GP20 PF06810.11 OWF42563.1 - 0.0086 15.9 13.0 0.33 10.7 5.1 2.4 1 1 1 2 2 2 2 Phage minor structural protein GP20 zf-C4H2 PF10146.9 OWF42563.1 - 0.0089 16.4 7.3 0.072 13.4 3.5 2.6 1 1 1 2 2 2 1 Zinc finger-containing protein CLZ PF16526.5 OWF42563.1 - 0.0093 16.3 5.1 1.7 9.1 0.7 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG6 PF06419.11 OWF42563.1 - 0.01 14.1 1.7 0.28 9.3 0.1 2.5 1 1 2 3 3 3 0 Conserved oligomeric complex COG6 Bacillus_HBL PF05791.11 OWF42563.1 - 0.011 15.5 5.7 0.98 9.2 1.3 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Apolipoprotein PF01442.18 OWF42563.1 - 0.012 15.5 2.4 0.024 14.5 2.4 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3972 PF13118.6 OWF42563.1 - 0.013 16.0 4.7 3 8.3 0.3 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3972) Sec3_C PF09763.9 OWF42563.1 - 0.013 14.0 2.7 0.17 10.3 0.1 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec3 AAA_13 PF13166.6 OWF42563.1 - 0.013 14.2 4.1 0.038 12.6 4.1 1.7 1 1 0 1 1 1 0 AAA domain HrpB7 PF09486.10 OWF42563.1 - 0.014 15.8 0.6 5.2 7.4 0.2 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TSC22 PF01166.18 OWF42563.1 - 0.015 15.6 5.6 18 5.7 0.0 5.3 2 1 3 5 5 3 0 TSC-22/dip/bun family HMMR_N PF15905.5 OWF42563.1 - 0.017 14.6 3.5 0.033 13.6 2.8 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Lambda_tail_I PF06805.12 OWF42563.1 - 0.019 15.3 0.1 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I HAP1_N PF04849.13 OWF42563.1 - 0.021 14.0 1.8 0.047 12.9 1.8 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Leu_zip PF15294.6 OWF42563.1 - 0.022 14.3 7.5 0.087 12.3 7.5 1.8 1 1 0 1 1 1 0 Leucine zipper DUF4677 PF15726.5 OWF42563.1 - 0.022 15.0 2.7 7.3 6.7 0.1 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4677) TMCO5 PF14992.6 OWF42563.1 - 0.022 14.4 2.5 0.025 14.1 0.5 1.8 1 1 1 2 2 2 0 TMCO5 family BicD PF09730.9 OWF42563.1 - 0.022 13.2 6.4 0.018 13.5 2.0 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D NleF_casp_inhib PF16809.5 OWF42563.1 - 0.025 14.5 6.0 0.55 10.1 1.6 2.6 1 1 2 3 3 3 0 NleF caspase inhibitor DUF4795 PF16043.5 OWF42563.1 - 0.026 14.2 5.5 2.4 7.7 1.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) RmuC PF02646.16 OWF42563.1 - 0.031 13.4 3.7 0.47 9.5 0.8 2.5 1 1 2 3 3 3 0 RmuC family Phycobilisome PF00502.19 OWF42563.1 - 0.032 14.2 0.3 6.2 6.7 0.0 2.6 1 1 0 2 2 2 0 Phycobilisome protein Laminin_I PF06008.14 OWF42563.1 - 0.033 13.9 5.3 0.042 13.5 1.2 2.1 1 1 1 2 2 2 0 Laminin Domain I DUF5320 PF17253.2 OWF42563.1 - 0.034 15.2 0.7 28 5.9 0.1 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5320) FlaC_arch PF05377.11 OWF42563.1 - 0.036 14.4 11.2 12 6.4 0.3 4.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF4988 PF16378.5 OWF42563.1 - 0.036 13.7 7.3 4.7 6.8 0.1 4.0 1 1 2 3 3 3 0 Domain of unknown function Syntaxin-6_N PF09177.11 OWF42563.1 - 0.041 14.4 3.4 0.77 10.3 0.9 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KxDL PF10241.9 OWF42563.1 - 0.043 14.1 4.0 6.2 7.2 0.1 3.6 1 1 3 4 4 4 0 Uncharacterized conserved protein GrpE PF01025.19 OWF42563.1 - 0.044 13.4 4.9 2.2 7.9 1.2 2.5 1 1 1 2 2 2 0 GrpE End3 PF12761.7 OWF42563.1 - 0.046 13.9 3.5 3.7 7.7 0.7 3.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Fib_alpha PF08702.10 OWF42563.1 - 0.05 13.8 5.5 0.12 12.5 2.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.18 OWF42563.1 - 0.054 12.8 0.2 0.054 12.8 0.2 3.2 1 1 3 4 4 3 0 CorA-like Mg2+ transporter protein SKA1 PF07160.12 OWF42563.1 - 0.054 13.3 6.6 0.42 10.4 0.4 3.0 2 1 2 4 4 3 0 Spindle and kinetochore-associated protein 1 Lebercilin PF15619.6 OWF42563.1 - 0.059 13.0 3.6 2.6 7.7 0.4 2.9 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.11 OWF42563.1 - 0.059 13.6 13.5 0.16 12.2 2.2 3.5 1 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF5082 PF16888.5 OWF42563.1 - 0.06 13.6 2.5 0.077 13.3 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HMMR_C PF15908.5 OWF42563.1 - 0.061 13.6 2.4 5.7 7.2 0.2 2.9 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal CtIP_N PF10482.9 OWF42563.1 - 0.063 13.3 2.2 7.4 6.6 0.3 2.6 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF724 PF05266.14 OWF42563.1 - 0.064 13.1 6.4 0.77 9.6 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF812 PF05667.11 OWF42563.1 - 0.066 12.1 4.9 0.29 10.0 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Tsc35 PF15079.6 OWF42563.1 - 0.069 12.7 10.3 1.7 8.2 3.7 2.5 2 0 0 2 2 2 0 Testis-specific protein 35 Use1 PF09753.9 OWF42563.1 - 0.071 12.8 5.6 0.49 10.1 0.2 2.7 3 0 0 3 3 2 0 Membrane fusion protein Use1 DivIVA PF05103.13 OWF42563.1 - 0.074 13.1 6.1 9.6 6.3 0.7 3.7 1 1 1 3 3 3 0 DivIVA protein FH2 PF02181.23 OWF42563.1 - 0.075 12.1 2.9 0.57 9.2 0.1 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain Tup_N PF08581.10 OWF42563.1 - 0.077 13.3 1.5 3.9 7.8 0.4 2.7 1 1 0 2 2 2 0 Tup N-terminal Phage_HK97_TLTM PF06120.11 OWF42563.1 - 0.081 12.1 8.4 2.5 7.2 2.5 2.1 1 1 1 2 2 2 0 Tail length tape measure protein Macoilin PF09726.9 OWF42563.1 - 0.081 11.5 5.4 0.012 14.2 0.8 1.7 2 0 0 2 2 2 0 Macoilin family CCDC144C PF14915.6 OWF42563.1 - 0.091 11.9 3.8 0.26 10.4 3.8 1.9 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region ATG16 PF08614.11 OWF42563.1 - 0.094 12.9 5.7 0.23 11.6 0.3 2.6 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 OWF42563.1 - 0.097 10.2 2.3 0.15 9.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RhoGEF67_u2 PF16614.5 OWF42563.1 - 0.1 12.7 0.3 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 APG6_N PF17675.1 OWF42563.1 - 0.11 13.0 1.1 0.67 10.5 1.1 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Syntaxin PF00804.25 OWF42563.1 - 0.11 12.1 5.9 0.86 9.2 2.4 2.2 1 1 1 2 2 2 0 Syntaxin TACC_C PF05010.14 OWF42563.1 - 0.16 11.7 4.4 0.29 10.9 2.5 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 OWF42563.1 - 0.17 12.1 2.7 5.3 7.2 0.8 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3782 PF12644.7 OWF42563.1 - 0.21 11.7 3.7 31 4.8 0.1 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF3782) HIP1_clath_bdg PF16515.5 OWF42563.1 - 0.22 12.1 2.5 6.9 7.4 0.5 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TNFR_c6 PF00020.18 OWF42563.1 - 0.23 11.9 31.2 0.72 10.3 7.7 4.5 5 0 0 5 5 3 0 TNFR/NGFR cysteine-rich region APG17 PF04108.12 OWF42563.1 - 0.24 10.5 7.0 1.3 8.1 2.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF3139 PF11337.8 OWF42563.1 - 0.26 12.0 4.0 0.36 11.5 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3139) DUF2730 PF10805.8 OWF42563.1 - 0.3 11.2 10.1 1.8 8.7 2.0 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) UPF0154 PF03672.13 OWF42563.1 - 0.31 11.1 1.1 1.5 8.9 0.1 2.4 3 0 0 3 3 1 0 Uncharacterised protein family (UPF0154) Spectrin PF00435.21 OWF42563.1 - 0.31 11.5 1.1 4.2 7.9 0.5 2.4 1 1 1 2 2 2 0 Spectrin repeat DUF3450 PF11932.8 OWF42563.1 - 0.33 10.2 1.3 1.2 8.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LRRFIP PF09738.9 OWF42563.1 - 0.36 10.3 7.0 0.64 9.4 7.0 1.3 1 0 0 1 1 1 0 LRRFIP family COG2 PF06148.11 OWF42563.1 - 0.36 10.9 2.8 9.7 6.3 0.4 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 OWF42563.1 - 0.39 10.8 4.3 2.9 8.0 2.5 2.5 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 OWF42563.1 - 0.42 10.8 9.5 1 9.6 2.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cast PF10174.9 OWF42563.1 - 0.44 8.7 7.7 0.71 8.0 7.7 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DivIC PF04977.15 OWF42563.1 - 0.47 10.3 6.0 27 4.6 0.5 3.8 1 1 3 4 4 4 0 Septum formation initiator T3SchapCesA PF11439.8 OWF42563.1 - 0.48 10.6 5.3 9.9 6.4 0.3 3.0 1 1 1 3 3 2 0 Type III secretion system filament chaperone CesA YkyA PF10368.9 OWF42563.1 - 0.51 10.0 7.4 2 8.0 0.5 2.2 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein MAD PF05557.13 OWF42563.1 - 0.63 8.3 5.9 1 7.6 5.9 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF3347 PF11827.8 OWF42563.1 - 0.69 10.1 8.1 2.9 8.0 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) CsbD PF05532.12 OWF42563.1 - 0.79 9.7 7.7 7.3 6.6 2.8 3.1 2 1 0 2 2 2 0 CsbD-like Vps51 PF08700.11 OWF42563.1 - 0.89 9.7 3.9 26 5.0 0.2 3.8 1 1 2 3 3 3 0 Vps51/Vps67 JAKMIP_CC3 PF16034.5 OWF42563.1 - 1.4 8.8 5.2 0.19 11.7 0.4 2.0 2 0 0 2 2 1 0 JAKMIP CC3 domain DUF677 PF05055.12 OWF42563.1 - 1.5 7.7 9.8 0.86 8.4 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Occludin_ELL PF07303.13 OWF42563.1 - 1.7 9.4 5.3 5.3 7.8 0.5 3.3 2 1 1 4 4 2 0 Occludin homology domain SOGA PF11365.8 OWF42563.1 - 1.8 9.8 5.9 10 7.3 0.6 2.6 2 1 1 3 3 2 0 Protein SOGA HALZ PF02183.18 OWF42563.1 - 1.8 8.9 7.0 19 5.6 0.3 3.8 2 2 1 3 3 3 0 Homeobox associated leucine zipper DUF4200 PF13863.6 OWF42563.1 - 1.8 9.0 4.3 6 7.3 1.8 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) betaPIX_CC PF16523.5 OWF42563.1 - 3.1 7.7 8.7 3.5 7.5 2.3 3.4 1 1 2 3 3 3 0 betaPIX coiled coil Muted PF14942.6 OWF42563.1 - 4.5 7.6 8.0 0.24 11.7 1.1 2.3 2 1 1 3 3 2 0 Organelle biogenesis, Muted-like protein CC2-LZ PF16516.5 OWF42563.1 - 4.8 7.6 8.2 44 4.5 2.2 3.1 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PGBA_C PF15437.6 OWF42563.1 - 5.1 7.5 12.0 11 6.4 0.2 3.3 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA C-terminal Prefoldin_2 PF01920.20 OWF42563.1 - 6.5 6.8 7.0 27 4.8 0.6 3.2 1 1 2 3 3 3 0 Prefoldin subunit DUF2312 PF10073.9 OWF42563.1 - 7.4 6.3 7.3 24 4.7 0.5 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Prefoldin_3 PF13758.6 OWF42563.1 - 8.6 6.5 6.9 35 4.5 0.6 3.4 2 1 1 3 3 2 0 Prefoldin subunit PEX-2N PF09263.10 OWF42564.1 - 2.7e-14 53.2 30.5 2e+02 2.4 0.0 20.1 1 1 42 44 44 44 0 Peroxisome biogenesis factor 1, N-terminal Rep_fac-A_3 PF08661.11 OWF42564.1 - 9.7e-11 42.0 137.0 5 7.5 1.5 22.8 1 1 37 38 38 38 36 Replication factor A protein 3 PapD_C PF02753.17 OWF42565.1 - 0.19 12.1 11.7 6 7.3 0.2 4.5 1 1 3 4 4 4 0 Pili assembly chaperone PapD, C-terminal domain Sde2_N_Ubi PF13019.6 OWF42565.1 - 4.2 7.2 12.9 1 9.1 3.0 2.5 1 1 1 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain DUF5102 PF17104.5 OWF42566.1 - 0.086 12.9 0.2 0.086 12.9 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) RelB PF04221.12 OWF42566.1 - 0.36 10.8 1.9 25 4.9 0.2 2.9 1 1 2 3 3 3 0 RelB antitoxin FAP PF07174.11 OWF42566.1 - 0.89 9.0 8.8 3.5 7.0 8.8 1.8 1 1 0 1 1 1 0 Fibronectin-attachment protein (FAP) HAGH_C PF16123.5 OWF42569.1 - 7.4e-21 74.5 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OWF42569.1 - 3.8e-12 46.6 5.0 2.5e-10 40.7 5.1 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OWF42569.1 - 0.0001 22.3 0.2 0.00079 19.4 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OWF42569.1 - 0.00071 19.1 0.1 0.0018 17.8 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lipase_GDSL PF00657.22 OWF42571.1 - 6.4e-17 62.2 0.1 1.1e-16 61.4 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF42571.1 - 1.7e-08 35.1 3.3 3e-07 31.0 3.3 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF42572.1 - 3.3e-23 82.7 0.0 5.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF42572.1 - 3.1e-08 34.2 2.4 4.5e-08 33.7 0.5 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.7 OWF42573.1 - 2.6e-08 34.3 0.0 1.2e-07 32.2 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF42573.1 - 6.2e-06 26.7 0.0 0.0031 18.1 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF42573.1 - 1.5e-05 25.3 0.0 0.27 11.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OWF42573.1 - 9.3e-05 22.6 0.0 0.00044 20.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF42573.1 - 0.025 15.1 0.0 35 5.4 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat JAKMIP_CC3 PF16034.5 OWF42573.1 - 0.063 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF4538 PF15061.6 OWF42574.1 - 0.064 13.0 0.1 15 5.4 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4538) Fascin PF06268.13 OWF42575.1 - 7e-66 219.4 1.4 7.6e-20 71.2 0.1 4.1 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.12 OWF42575.1 - 2.1e-19 70.0 1.8 8.9e-08 32.1 0.0 4.8 4 2 3 7 7 7 4 FRG1-like domain DUF569 PF04601.13 OWF42575.1 - 0.00031 20.4 0.5 0.062 13.0 0.0 3.4 2 2 2 4 4 4 2 Domain of unknown function (DUF569) RicinB_lectin_2 PF14200.6 OWF42575.1 - 0.003 18.3 3.7 18 6.2 1.3 4.3 3 2 0 4 4 4 1 Ricin-type beta-trefoil lectin domain-like HLH PF00010.26 OWF42576.1 - 4e-17 61.9 1.0 8.7e-17 60.8 1.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 OWF42576.1 - 1.3e-13 52.3 8.2 1.3e-13 52.3 8.2 2.5 2 1 1 3 3 3 1 Neuronal helix-loop-helix transcription factor RBR PF17208.3 OWF42576.1 - 0.016 15.9 5.8 0.016 15.9 5.8 1.8 2 0 0 2 2 2 0 RNA binding Region CDC45 PF02724.14 OWF42576.1 - 0.63 8.3 6.2 0.81 7.9 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein HCO3_cotransp PF00955.21 OWF42577.1 - 7.6e-219 727.7 7.5 9.5e-219 727.4 7.5 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 OWF42577.1 - 1e-70 238.7 0.0 1.5e-70 238.1 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain SesA PF17107.5 OWF42577.1 - 0.079 13.2 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Nucleos_tra2_C PF07662.13 OWF42578.1 - 1.4e-74 250.5 7.8 3.3e-74 249.2 7.8 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF42578.1 - 8.1e-18 64.8 3.8 8.1e-18 64.8 3.8 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OWF42578.1 - 5.4e-08 33.1 7.3 5.4e-08 33.1 7.3 3.1 4 0 0 4 4 4 1 Nucleoside recognition EbsA PF17255.2 OWF42579.1 - 0.018 15.4 12.6 1.3 9.3 4.3 3.1 1 1 2 3 3 3 0 EbsA-like protein DUF2418 PF10332.9 OWF42580.1 - 1 10.0 6.8 35 5.0 0.0 4.5 1 1 2 4 4 4 0 Protein of unknown function (DUF2418) Reeler PF02014.16 OWF42581.1 - 3.7e-15 56.8 0.0 5.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Reeler domain Acyl_transf_3 PF01757.22 OWF42582.1 - 6.7e-22 78.0 42.5 1.1e-21 77.3 42.5 1.3 1 0 0 1 1 1 1 Acyltransferase family PHAT PF09246.10 OWF42582.1 - 0.12 12.2 0.3 0.3 10.9 0.3 1.6 1 0 0 1 1 1 0 PHAT Acyl_transf_3 PF01757.22 OWF42583.1 - 6.7e-21 74.7 43.5 1e-20 74.1 43.5 1.3 1 0 0 1 1 1 1 Acyltransferase family PHAT PF09246.10 OWF42583.1 - 0.003 17.4 0.2 0.0071 16.2 0.2 1.6 1 0 0 1 1 1 1 PHAT PHAT PF09246.10 OWF42584.1 - 0.018 14.8 0.1 0.049 13.4 0.1 1.8 1 0 0 1 1 1 0 PHAT Acyl_transf_3 PF01757.22 OWF42585.1 - 2.8e-14 53.0 38.8 2.8e-14 53.0 38.8 1.5 2 0 0 2 2 2 1 Acyltransferase family Glyco_hydro_11 PF00457.17 OWF42585.1 - 0.024 14.3 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 Cystatin PF00031.21 OWF42586.1 - 1.8e-27 95.4 0.1 0.00072 19.8 0.0 9.0 8 1 0 8 8 8 6 Cystatin domain SQAPI PF16845.5 OWF42586.1 - 7.9e-16 58.2 4.2 0.0077 16.6 0.0 8.3 9 0 0 9 9 9 5 Aspartic acid proteinase inhibitor Rad9_Rad53_bind PF08605.10 OWF42586.1 - 0.00025 21.3 0.1 17 5.6 0.0 5.4 5 1 1 6 6 6 1 Fungal Rad9-like Rad53-binding DUF2126 PF09899.9 OWF42586.1 - 0.1 10.6 0.0 1.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) p450 PF00067.22 OWF42587.1 - 1.3e-110 370.4 0.0 1.6e-110 370.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PMP1_2 PF08114.11 OWF42587.1 - 0.043 13.5 1.8 0.16 11.7 0.4 2.2 2 0 0 2 2 2 0 ATPase proteolipid family Y_phosphatase PF00102.27 OWF42588.1 - 2.6e-86 289.0 0.4 2.6e-57 194.1 1.3 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase RIFIN PF02009.16 OWF42588.1 - 0.012 15.6 0.3 0.025 14.5 0.3 1.4 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 OWF42588.1 - 0.012 16.4 0.0 0.029 15.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rer1 PF03248.13 OWF42588.1 - 0.03 14.0 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Rer1 family RRM_1 PF00076.22 OWF42589.1 - 2.9e-32 110.3 0.5 2e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF42589.1 - 2.1e-11 43.8 0.3 9.6e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OWF42589.1 - 8.8e-05 22.4 0.0 0.0055 16.7 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 OWF42589.1 - 0.038 13.9 0.0 0.7 9.9 0.0 2.4 2 1 0 2 2 2 0 RL domain EF-hand_6 PF13405.6 OWF42590.1 - 6.4e-19 66.2 9.8 0.0067 16.3 0.0 8.9 10 0 0 10 10 10 5 EF-hand domain EF-hand_1 PF00036.32 OWF42590.1 - 4e-16 57.3 0.5 0.015 14.8 0.0 7.9 7 0 0 7 7 7 5 EF hand EF-hand_7 PF13499.6 OWF42590.1 - 2.2e-15 56.9 19.0 0.0023 18.4 0.2 7.3 6 1 0 6 6 6 4 EF-hand domain pair EF-hand_11 PF08976.11 OWF42590.1 - 1.9e-08 35.1 6.3 0.0079 17.1 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain RST PF12174.8 OWF42590.1 - 1.6e-06 27.9 9.7 2.1 8.3 0.0 7.0 6 1 0 6 6 6 3 RCD1-SRO-TAF4 (RST) plant domain EF-hand_8 PF13833.6 OWF42590.1 - 1.1e-05 25.2 2.3 12 5.8 0.0 6.4 6 0 0 6 6 6 2 EF-hand domain pair DMAP1 PF05499.12 OWF42590.1 - 0.0097 15.8 0.5 0.025 14.4 0.5 1.7 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) EF-hand_9 PF14658.6 OWF42590.1 - 0.092 13.1 0.3 10 6.5 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain C2 PF00168.30 OWF42591.1 - 1.4e-44 150.6 1.4 6e-23 81.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 OWF42591.1 - 3.5e-05 23.7 0.5 0.0025 17.7 0.1 2.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.6 OWF42591.1 - 0.032 14.0 2.2 0.67 9.7 0.1 2.4 1 1 1 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Trp_dioxygenase PF03301.13 OWF42591.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase DUF4550 PF15084.6 OWF42591.1 - 0.15 12.5 0.3 0.36 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) PPR_long PF17177.4 OWF42593.1 - 9.9e-05 21.8 0.2 1.6 8.0 0.1 3.0 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_long PF17177.4 OWF42594.1 - 0.00032 20.1 0.5 0.38 10.1 0.0 3.0 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP Peripla_BP_7 PF18610.1 OWF42594.1 - 2.2 8.5 3.9 18 5.5 0.3 2.9 1 1 1 2 2 2 0 Periplasmic binding protein domain VCX_VCY PF15231.6 OWF42596.1 - 9.8e-13 49.0 0.0 2 9.1 0.0 8.1 2 2 8 10 10 10 5 Variable charge X/Y family Kelch_6 PF13964.6 OWF42596.1 - 0.011 15.9 7.5 15 6.0 1.0 5.9 4 2 1 5 5 5 0 Kelch motif EF-hand_7 PF13499.6 OWF42597.1 - 7.7e-15 55.1 3.8 1.2e-10 41.6 0.3 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF42597.1 - 2.7e-13 48.4 7.7 0.00011 21.5 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OWF42597.1 - 3.5e-13 48.4 2.1 5.3e-05 22.5 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OWF42597.1 - 8.7e-11 40.9 4.0 0.0018 18.1 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF42597.1 - 3e-09 36.6 7.5 1e-05 25.2 0.1 4.2 3 2 1 4 4 4 2 EF-hand domain pair ALO PF04030.14 OWF42597.1 - 0.0055 16.5 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Mic1 PF07035.12 OWF42597.1 - 0.02 14.6 0.3 0.034 13.8 0.3 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like EF-hand_9 PF14658.6 OWF42597.1 - 0.031 14.6 0.8 7.4 7.0 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain DUF3417 PF11897.8 OWF42598.1 - 0.0078 16.7 1.4 0.014 15.8 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3417) CBS PF00571.28 OWF42599.1 - 2.6e-31 107.8 8.7 6.3e-10 39.3 0.9 4.9 5 0 0 5 5 5 4 CBS domain Thioredoxin_6 PF13848.6 OWF42599.1 - 0.052 13.5 0.4 0.14 12.1 0.4 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain SSF PF00474.17 OWF42600.1 - 2.5e-121 405.4 17.2 3.3e-121 405.0 17.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4231 PF14015.6 OWF42600.1 - 0.013 15.9 6.0 2.5 8.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) NNMT_PNMT_TEMT PF01234.17 OWF42601.1 - 2.2e-44 151.5 0.0 2.8e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 OWF42601.1 - 8.6e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42601.1 - 0.006 16.4 0.1 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF42601.1 - 0.016 15.9 0.0 0.055 14.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SSF PF00474.17 OWF42602.1 - 2.6e-121 405.3 20.4 3.6e-121 404.9 20.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4231 PF14015.6 OWF42602.1 - 0.023 15.2 3.7 2.7 8.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Methyltransf_25 PF13649.6 OWF42603.1 - 0.00067 20.3 0.0 0.0011 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 OWF42603.1 - 0.0015 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 OWF42603.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF42603.1 - 0.0079 16.8 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF42603.1 - 0.01 15.2 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 OWF42603.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 OWF42603.1 - 0.02 15.6 0.0 0.032 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42603.1 - 0.022 14.5 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrgI PF12666.7 OWF42603.1 - 0.081 13.6 0.0 0.35 11.6 0.0 1.9 2 0 0 2 2 2 0 PrgI family protein MTS PF05175.14 OWF42603.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AICARFT_IMPCHas PF01808.18 OWF42604.1 - 3.9e-94 315.4 0.0 5.1e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OWF42604.1 - 2.3e-22 79.0 0.0 4.4e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Med28 PF11594.8 OWF42605.1 - 0.023 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 Herpes_glycop PF01528.16 OWF42605.1 - 0.04 12.8 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M NINJA_B PF16136.5 OWF42605.1 - 0.06 13.7 0.2 0.094 13.1 0.2 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal Corona_I PF03187.14 OWF42605.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Corona nucleocapsid I protein Zip PF02535.22 OWF42605.1 - 0.24 10.6 0.4 0.29 10.3 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-C_C PF11699.8 OWF42606.1 - 2.1e-17 63.1 0.1 5e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.11 OWF42606.1 - 0.0092 15.7 0.1 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Ldl_recept_a PF00057.18 OWF42607.1 - 3.6 7.9 15.4 4.1 7.7 2.2 4.1 3 1 1 4 4 4 0 Low-density lipoprotein receptor domain class A Claudin_3 PF06653.11 OWF42608.1 - 0.00022 21.2 15.9 0.00033 20.7 15.9 1.3 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 OWF42609.1 - 1.4e-05 25.0 11.7 0.0055 16.5 8.2 2.8 1 1 2 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF42609.1 - 0.0049 16.8 12.3 0.024 14.6 12.3 2.1 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Adipogenin PF15202.6 OWF42609.1 - 0.62 10.1 0.1 0.62 10.1 0.1 2.5 3 0 0 3 3 3 0 Adipogenin Sensor PF13796.6 OWF42609.1 - 1.9 8.5 11.4 4 7.5 1.1 2.5 2 0 0 2 2 2 0 Putative sensor DUF4131 PF13567.6 OWF42609.1 - 2.5 7.7 9.9 13 5.4 1.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Claudin_2 PF13903.6 OWF42610.1 - 4.4e-05 23.3 13.9 0.0015 18.3 13.9 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction OppC_N PF12911.7 OWF42610.1 - 7.2 6.7 9.3 25 4.9 2.1 3.4 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Claudin_2 PF13903.6 OWF42611.1 - 5.6e-08 32.8 10.4 1.6e-05 24.7 10.4 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF42611.1 - 0.004 17.1 13.5 0.048 13.6 13.9 2.3 1 1 1 2 2 2 1 Tight junction protein, Claudin-like DUF4131 PF13567.6 OWF42611.1 - 0.062 12.9 9.7 0.86 9.2 2.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Prominin PF05478.11 OWF42611.1 - 0.11 10.4 4.9 0.2 9.6 4.9 1.4 1 0 0 1 1 1 0 Prominin EphA2_TM PF14575.6 OWF42611.1 - 0.16 12.9 1.0 13 6.8 0.0 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Amastin PF07344.11 OWF42611.1 - 0.34 10.8 10.6 0.53 10.1 10.6 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein Virul_fac_BrkB PF03631.15 OWF42611.1 - 0.54 9.8 14.1 0.35 10.4 2.6 2.1 2 0 0 2 2 2 0 Virulence factor BrkB Clc-like PF07062.12 OWF42611.1 - 0.7 9.3 9.9 1.2 8.5 0.3 2.2 1 1 0 2 2 2 0 Clc-like TRP PF06011.12 OWF42611.1 - 0.92 8.2 5.3 1.1 7.9 2.8 2.0 1 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel DUF2207 PF09972.9 OWF42611.1 - 3.1 6.5 16.9 1.2 7.8 0.2 2.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ost5 PF05251.12 OWF42611.1 - 4.2 7.7 19.1 0.66 10.3 0.7 3.8 3 1 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Claudin_2 PF13903.6 OWF42612.1 - 2.7e-05 24.0 15.9 0.00031 20.6 15.9 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF42612.1 - 1.2 9.0 17.3 3.2 7.7 17.3 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Claudin_3 PF06653.11 OWF42613.1 - 0.015 15.3 9.4 0.065 13.2 9.4 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like HlyIII PF03006.20 OWF42613.1 - 0.4 10.3 8.8 1.5 8.5 8.0 2.0 1 1 1 2 2 2 0 Haemolysin-III related IBR PF01485.21 OWF42615.1 - 0.0053 17.0 2.4 0.0053 17.0 2.4 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain YozE_SAM_like PF06855.12 OWF42615.1 - 0.22 11.7 3.7 0.41 10.8 0.2 3.0 3 0 0 3 3 3 0 YozE SAM-like fold IBR PF01485.21 OWF42616.1 - 0.0017 18.6 1.5 0.0017 18.6 1.5 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain CUE PF02845.16 OWF42616.1 - 0.015 15.0 0.2 0.015 15.0 0.2 4.4 5 0 0 5 5 5 0 CUE domain MHB PF16525.5 OWF42616.1 - 0.022 15.0 3.4 0.074 13.3 0.1 3.4 4 0 0 4 4 4 0 Haemophore, haem-binding FH2 PF02181.23 OWF42617.1 - 5.5e-21 75.1 5.5 5.5e-21 75.1 5.5 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Mt_ATP-synt_D PF05873.12 OWF42617.1 - 0.0014 18.5 1.8 0.0041 17.0 1.8 1.8 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF5344 PF17279.2 OWF42617.1 - 3.4 8.3 9.0 9.7 6.9 1.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5344) TPR_12 PF13424.6 OWF42619.1 - 7.8e-26 90.2 14.6 7.1e-12 45.5 0.1 5.2 3 2 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42619.1 - 1.8e-16 58.8 23.2 0.0028 17.6 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 OWF42619.1 - 7.4e-16 57.2 23.2 1.3e-05 24.8 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF42619.1 - 4.1e-13 48.4 9.4 0.00046 20.0 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF42619.1 - 1.7e-12 46.5 14.4 0.0039 17.3 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 OWF42619.1 - 1.7e-10 40.4 11.6 0.018 14.9 0.2 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OWF42619.1 - 5.7e-08 33.3 18.3 0.072 13.8 0.0 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF42619.1 - 2.5e-05 23.8 4.5 0.11 12.2 0.0 5.1 4 1 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 OWF42619.1 - 0.00051 20.6 13.9 1.4 9.9 0.0 7.0 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF42619.1 - 0.0021 17.5 5.0 0.22 10.8 0.7 3.6 1 1 1 3 3 3 1 MalT-like TPR region TPR_19 PF14559.6 OWF42619.1 - 0.0038 17.7 15.0 1.5 9.4 0.4 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.9 OWF42619.1 - 0.13 12.0 0.0 0.13 12.0 0.0 3.7 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 OWF42619.1 - 0.27 11.4 7.7 19 5.5 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF42619.1 - 0.31 11.5 11.0 8.3 7.0 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 OWF42619.1 - 0.51 10.7 3.6 59 4.1 0.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF42619.1 - 5.2 7.9 17.3 51 4.8 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat MIT PF04212.18 OWF42619.1 - 9 6.5 12.7 6.1 7.0 0.2 5.5 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Mak10 PF04112.13 OWF42620.1 - 1e-29 103.2 6.9 1.2e-23 83.4 0.4 3.6 3 1 1 4 4 4 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF2203 PF09969.9 OWF42620.1 - 0.26 12.0 0.1 0.26 12.0 0.1 2.8 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) Xan_ur_permease PF00860.20 OWF42621.1 - 4.4e-84 282.4 32.7 6.7e-84 281.8 32.7 1.3 1 0 0 1 1 1 1 Permease family MIB_HERC2 PF06701.13 OWF42623.1 - 2.3e-21 75.8 18.5 9e-15 54.7 3.5 3.3 3 0 0 3 3 3 2 Mib_herc2 VWA_2 PF13519.6 OWF42623.1 - 8.6e-09 36.0 0.9 3.3e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OWF42623.1 - 1.3e-07 32.1 0.0 3.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain SOAR PF16533.5 OWF42623.1 - 0.022 14.7 0.6 0.066 13.2 0.6 1.8 1 0 0 1 1 1 0 STIM1 Orai1-activating region FliT PF05400.13 OWF42623.1 - 0.38 11.6 3.7 1.2 10.0 3.1 2.1 1 1 1 2 2 2 0 Flagellar protein FliT DUF4314 PF14192.6 OWF42623.1 - 0.57 10.1 6.8 2.7 8.0 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) Fib_alpha PF08702.10 OWF42623.1 - 0.7 10.1 4.3 0.3 11.3 0.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 OWF42623.1 - 1.7 6.5 7.9 3.5 5.4 7.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VWA PF00092.28 OWF42624.1 - 3.1e-10 40.6 0.0 2.9e-09 37.4 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF42624.1 - 3.6e-07 30.8 0.0 3.8e-06 27.5 0.0 2.6 2 1 1 3 3 3 1 von Willebrand factor type A domain MIB_HERC2 PF06701.13 OWF42625.1 - 3.6e-19 68.8 12.9 8.6e-11 41.9 0.5 2.7 2 0 0 2 2 2 2 Mib_herc2 VWA_2 PF13519.6 OWF42625.1 - 8.3e-09 36.1 0.0 3.3e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF42625.1 - 1.1e-08 35.5 0.0 3.5e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Laminin_II PF06009.12 OWF42625.1 - 0.064 13.3 0.5 0.15 12.0 0.5 1.6 1 0 0 1 1 1 0 Laminin Domain II Ets PF00178.22 OWF42626.1 - 2.1e-36 124.2 0.1 3.9e-36 123.4 0.1 1.5 1 0 0 1 1 1 1 Ets-domain ETS_PEA3_N PF04621.13 OWF42626.1 - 2.9e-24 86.6 25.7 2.9e-24 86.6 25.7 2.7 2 1 0 2 2 2 1 PEA3 subfamily ETS-domain transcription factor N terminal domain HSF_DNA-bind PF00447.17 OWF42626.1 - 0.093 13.4 0.1 1.2 9.8 0.0 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding DAGK_acc PF00609.19 OWF42627.1 - 4.6e-52 176.6 0.0 1.2e-51 175.2 0.0 1.8 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.6 OWF42627.1 - 6e-44 150.2 2.2 1e-43 149.5 0.5 2.2 2 1 0 2 2 2 1 Diacylglycerol kinase N-terminus DAGK_cat PF00781.24 OWF42627.1 - 9.2e-27 93.2 0.0 2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 OWF42627.1 - 1.8e-23 82.2 29.5 7.7e-13 48.1 7.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 OWF42627.1 - 1.5e-10 39.9 1.8 0.00022 20.5 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OWF42627.1 - 3.9e-08 33.6 0.6 1.2e-07 32.1 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF42627.1 - 4.6e-07 29.0 2.8 0.013 15.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OWF42627.1 - 4.8e-07 29.2 0.5 0.0017 18.1 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OWF42627.1 - 0.00015 21.5 0.1 0.28 11.1 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF42627.1 - 0.043 14.2 0.1 0.32 11.3 0.1 2.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region C1_2 PF03107.16 OWF42627.1 - 0.096 13.0 18.4 1.4 9.3 4.8 2.6 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 OWF42627.1 - 1.8 8.5 21.8 4.9 7.1 5.5 2.6 2 0 0 2 2 2 0 PHD-finger Baculo_19 PF04798.12 OWF42628.1 - 0.017 14.9 0.0 0.037 13.7 0.0 1.5 2 0 0 2 2 2 0 Baculovirus 19 kDa protein conserved region Neurexophilin PF06312.12 OWF42629.1 - 4.6e-07 29.5 0.0 9.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF42629.1 - 0.074 13.9 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat RRM_1 PF00076.22 OWF42630.1 - 5.1e-12 45.4 0.0 1.7e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ldh_1_C PF02866.18 OWF42631.1 - 6.1e-16 58.8 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OWF42631.1 - 3.8e-10 40.0 0.2 7.4e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain CDV3 PF15359.6 OWF42632.1 - 1.4e-23 83.8 19.4 1.4e-23 83.8 19.4 2.5 2 1 0 2 2 2 1 Carnitine deficiency-associated protein 3 SDA1 PF05285.12 OWF42632.1 - 1 8.7 28.7 1.7 8.0 28.7 1.3 1 0 0 1 1 1 0 SDA1 GGACT PF06094.12 OWF42633.1 - 2.2e-20 73.5 0.0 1e-19 71.3 0.0 1.8 1 1 1 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like MENTAL PF10457.9 OWF42634.1 - 1.9e-60 203.7 4.4 2.5e-60 203.3 4.4 1.2 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 OWF42634.1 - 1.5e-29 102.9 0.0 2.3e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 START domain SLATT_4 PF18186.1 OWF42634.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 FYVE PF01363.21 OWF42635.1 - 2.5e-16 59.5 14.0 8e-16 57.9 14.0 1.9 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 OWF42635.1 - 7.5e-09 35.7 0.0 7.5e-09 35.7 0.0 4.3 4 1 0 4 4 3 1 RUN domain ATG16 PF08614.11 OWF42635.1 - 6.6e-05 23.2 22.0 6.6e-05 23.2 22.0 11.2 2 2 8 10 10 9 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OWF42635.1 - 0.0016 18.5 32.5 0.0016 18.5 32.5 13.1 2 2 12 14 14 11 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 OWF42635.1 - 0.0022 18.0 21.8 0.0022 18.0 21.8 15.3 2 2 12 16 16 10 3 BRE1 E3 ubiquitin ligase JIP_LZII PF16471.5 OWF42635.1 - 0.0045 17.1 4.1 0.0045 17.1 4.1 18.4 13 8 5 19 19 17 2 JNK-interacting protein leucine zipper II Fib_alpha PF08702.10 OWF42635.1 - 0.0075 16.5 7.8 0.0075 16.5 7.8 13.3 3 2 8 13 13 13 4 Fibrinogen alpha/beta chain family GOLD_2 PF13897.6 OWF42635.1 - 0.019 15.4 0.0 0.019 15.4 0.0 6.4 6 1 1 7 7 3 0 Golgi-dynamics membrane-trafficking IBR PF01485.21 OWF42635.1 - 0.082 13.1 12.6 0.38 11.0 12.6 2.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 OWF42635.1 - 0.67 10.2 4.9 2.3 8.4 4.9 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF42635.1 - 1.3 9.4 11.9 3.6 8.0 11.9 1.8 1 0 0 1 1 1 0 Ring finger domain AOX PF01786.17 OWF42636.1 - 2.3e-91 305.2 0.6 2.9e-91 304.8 0.6 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF4314 PF14192.6 OWF42637.1 - 1.4 8.9 5.7 17 5.4 1.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4314) CpeT PF06206.11 OWF42637.1 - 3.7 7.5 8.7 5.8e+02 0.3 8.7 2.9 1 1 0 1 1 1 0 CpeT/CpcT family (DUF1001) SSF PF00474.17 OWF42638.1 - 1.5e-134 448.9 25.0 2e-134 448.5 25.0 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Sigma_reg_N PF13800.6 OWF42638.1 - 0.22 11.8 0.1 0.22 11.8 0.1 4.2 5 0 0 5 5 5 0 Sigma factor regulator N-terminal Kelch_1 PF01344.25 OWF42639.1 - 3.6e-91 298.5 20.9 3.4e-16 58.6 0.4 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF42639.1 - 7.9e-48 159.3 9.6 2.9e-08 33.7 0.0 6.6 3 2 4 7 7 6 6 Kelch motif BACK PF07707.15 OWF42639.1 - 2.4e-37 127.2 0.4 4.9e-37 126.2 0.1 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 OWF42639.1 - 1.9e-33 114.2 5.4 3.5e-06 26.9 0.0 6.4 2 2 4 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 OWF42639.1 - 1.8e-31 108.7 3.0 1.9e-31 108.6 1.2 1.9 2 1 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 OWF42639.1 - 5.1e-28 96.8 12.8 2.1e-05 24.7 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF42639.1 - 1.5e-27 94.5 7.8 5.1e-05 23.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 OWF42639.1 - 7.9e-08 32.1 1.9 8.8 6.4 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Glu_cyclase_2 PF05096.12 OWF42639.1 - 0.0037 16.7 0.0 4.2 6.7 0.0 2.9 2 1 0 3 3 3 2 Glutamine cyclotransferase Glyoxal_oxid_N PF07250.11 OWF42639.1 - 0.11 11.6 0.6 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus BA14K PF07886.11 OWF42639.1 - 0.86 9.5 3.3 27 4.8 0.0 3.5 4 0 0 4 4 4 0 BA14K-like protein Insulin_TMD PF17870.1 OWF42640.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment HGWP PF03578.15 OWF42640.1 - 1 8.9 3.9 2.1 7.9 3.9 1.5 1 0 0 1 1 1 0 HGWP repeat Itfg2 PF15907.5 OWF42641.1 - 1.9e-135 451.2 2.3 1.5e-132 441.7 0.4 2.7 2 1 0 2 2 2 2 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 OWF42641.1 - 2.2e-13 50.2 1.5 0.0082 16.2 0.1 4.5 3 2 2 5 5 5 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 OWF42641.1 - 1.8e-11 44.5 0.6 0.008 16.7 0.0 5.2 3 2 3 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OWF42641.1 - 5.3e-07 29.6 3.8 0.0064 16.6 0.7 4.2 5 0 0 5 5 5 2 FG-GAP repeat BBS1 PF14779.6 OWF42641.1 - 0.0026 17.3 1.2 0.45 9.9 0.0 3.6 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 1 PliI PF16743.5 OWF42641.1 - 0.0027 17.4 0.9 1 9.1 0.1 3.8 5 0 0 5 5 5 1 Periplasmic lysozyme inhibitor of I-type lysozyme PHTB1_N PF14727.6 OWF42641.1 - 0.0037 16.7 0.0 0.31 10.4 0.0 2.4 2 1 0 2 2 2 1 PTHB1 N-terminus BBS2_C PF14782.6 OWF42641.1 - 0.0075 15.1 0.5 1 8.0 0.0 3.0 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal WDCP PF15390.6 OWF42641.1 - 0.076 11.4 0.0 0.18 10.2 0.0 1.5 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family PhyH PF05721.13 OWF42642.1 - 1.6e-32 113.5 0.0 2.2e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OWF42642.1 - 0.00071 18.4 0.0 0.16 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) FMO-like PF00743.19 OWF42643.1 - 2e-183 610.6 0.0 2.5e-183 610.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF42643.1 - 8.9e-22 77.7 0.0 2.4e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF42643.1 - 2.1e-12 46.8 0.1 2.9e-09 36.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OWF42643.1 - 4.2e-12 45.9 0.0 2.6e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF42643.1 - 0.0011 19.2 0.0 0.0032 17.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OWF42643.1 - 0.0011 19.5 0.3 0.22 12.1 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF42643.1 - 0.0035 16.6 0.2 2.3 7.4 0.0 2.5 3 0 0 3 3 3 2 Thi4 family IlvN PF07991.12 OWF42643.1 - 0.025 14.1 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 OWF42643.1 - 0.039 13.0 0.2 0.47 9.5 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF42643.1 - 0.083 12.2 0.0 6.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OWF42643.1 - 0.11 11.1 0.1 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Peptidase_M17_N PF02789.17 OWF42643.1 - 0.16 11.9 0.2 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.24 OWF42643.1 - 0.19 11.3 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ependymin PF00811.18 OWF42644.1 - 6.2e-17 62.0 0.1 8.2e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Ependymin Lipocalin_2 PF08212.12 OWF42644.1 - 0.07 13.1 0.0 0.46 10.4 0.0 2.0 1 1 0 2 2 2 0 Lipocalin-like domain O-FucT PF10250.9 OWF42645.1 - 4.9e-84 282.9 0.0 5.8e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RepC PF06504.11 OWF42645.1 - 0.03 13.5 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Replication protein C (RepC) DUF2922 PF11148.8 OWF42645.1 - 0.091 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) DUF4483 PF14825.6 OWF42646.1 - 1e-30 106.6 0.3 1.6e-30 106.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) G-patch PF01585.23 OWF42647.1 - 1e-12 47.7 0.5 1.8e-12 46.9 0.5 1.4 1 0 0 1 1 1 1 G-patch domain zf-CCCH_4 PF18044.1 OWF42647.1 - 0.0043 16.8 3.5 0.0043 16.8 3.5 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 OWF42647.1 - 0.06 13.3 3.5 0.13 12.2 3.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF42647.1 - 0.19 11.8 2.8 1.1 9.4 2.8 2.2 1 1 0 1 1 1 0 Zinc finger domain DUF5499 PF17603.2 OWF42647.1 - 1.8 9.2 6.8 3.3 8.4 0.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5499) SDP_N PF12278.8 OWF42647.1 - 3 8.0 15.9 6.8 6.8 15.9 1.6 1 0 0 1 1 1 0 Sex determination protein N terminal Neur_chan_LBD PF02931.23 OWF42649.1 - 3.7e-44 150.7 1.2 4.3e-44 150.6 1.2 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Ribosomal_L5e PF17144.4 OWF42650.1 - 6.2e-90 299.5 0.3 1.1e-89 298.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OWF42650.1 - 1.4e-34 118.9 3.5 1.4e-34 118.9 3.5 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 OWF42650.1 - 0.0046 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta Lsr2 PF11774.8 OWF42650.1 - 0.31 11.2 3.0 0.38 10.9 1.7 1.8 2 0 0 2 2 2 0 Lsr2 ATG16 PF08614.11 OWF42651.1 - 0.01 16.1 26.9 0.01 16.1 26.9 14.3 3 1 9 12 12 12 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 OWF42651.1 - 0.26 11.2 0.0 0.26 11.2 0.0 10.1 11 0 0 11 11 11 0 Viral A-type inclusion protein repeat DEAD PF00270.29 OWF42652.1 - 1.1e-38 132.8 0.5 1.9e-38 132.0 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF42652.1 - 2.3e-26 92.3 1.2 8.7e-25 87.2 0.3 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF42652.1 - 2.1e-09 37.6 0.1 4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OWF42652.1 - 0.00029 20.3 0.2 0.00058 19.3 0.2 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RNA_pol_Rpb2_5 PF04567.17 OWF42652.1 - 0.029 14.9 0.1 11 6.7 0.1 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 UPF0184 PF03670.13 OWF42653.1 - 3.2e-15 56.3 9.6 7.9e-15 55.0 9.6 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) AAA_13 PF13166.6 OWF42653.1 - 0.0018 17.1 1.9 0.002 16.9 1.9 1.0 1 0 0 1 1 1 1 AAA domain ZapB PF06005.12 OWF42653.1 - 0.0031 17.9 4.2 0.0071 16.8 4.2 1.5 1 0 0 1 1 1 1 Cell division protein ZapB BRE1 PF08647.11 OWF42653.1 - 0.0031 17.5 2.1 0.0051 16.9 2.1 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase DUF615 PF04751.14 OWF42653.1 - 0.0039 17.2 1.4 0.0051 16.8 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF615) Med28 PF11594.8 OWF42653.1 - 0.0062 16.6 0.8 0.0082 16.2 0.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 28 Imm6 PF14434.6 OWF42653.1 - 0.011 15.6 1.3 0.015 15.2 1.3 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 DHR10 PF18595.1 OWF42653.1 - 0.019 15.0 5.2 0.03 14.4 5.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain PTRF_SDPR PF15237.6 OWF42653.1 - 0.021 14.5 1.7 0.024 14.3 1.7 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Spc7 PF08317.11 OWF42653.1 - 0.031 13.1 3.9 0.033 13.1 3.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein THOC7 PF05615.13 OWF42653.1 - 0.041 14.2 2.6 0.049 13.9 2.6 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 JIP_LZII PF16471.5 OWF42653.1 - 0.044 14.0 3.8 0.09 13.0 2.4 1.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Syntaxin_2 PF14523.6 OWF42653.1 - 0.047 14.1 4.2 0.058 13.8 4.2 1.2 1 0 0 1 1 1 0 Syntaxin-like protein DUF241 PF03087.14 OWF42653.1 - 0.048 13.5 1.6 0.056 13.3 0.4 1.6 1 1 1 2 2 2 0 Arabidopsis protein of unknown function AvrLm4-7 PF18661.1 OWF42653.1 - 0.053 14.5 1.6 0.6 11.2 0.1 2.1 1 1 1 2 2 2 0 Avirulence Effector AvrLm4-7 PRP1_N PF06424.12 OWF42653.1 - 0.064 13.7 8.2 0.87 10.0 8.2 2.0 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Nnf1 PF03980.14 OWF42653.1 - 0.076 13.4 0.3 0.076 13.4 0.3 2.3 1 1 1 2 2 2 0 Nnf1 BLOC1_2 PF10046.9 OWF42653.1 - 0.092 13.1 4.0 1.9 8.8 2.3 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 OWF42653.1 - 0.093 13.0 0.8 0.23 11.7 0.4 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MCC-bdg_PDZ PF10506.9 OWF42653.1 - 0.1 12.6 2.2 0.2 11.7 1.9 1.6 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4559 PF15112.6 OWF42653.1 - 0.17 11.5 5.8 0.18 11.5 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ADIP PF11559.8 OWF42653.1 - 0.2 11.7 6.8 0.17 12.0 5.7 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 OWF42653.1 - 0.26 12.0 4.7 0.046 14.4 1.5 1.5 2 0 0 2 2 1 0 Initiation control protein YabA TMPIT PF07851.13 OWF42653.1 - 0.28 10.4 1.5 0.35 10.1 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein DASH_Spc19 PF08287.11 OWF42653.1 - 0.3 11.0 6.3 0.12 12.3 4.1 1.4 1 1 1 2 2 2 0 Spc19 UPF0242 PF06785.11 OWF42653.1 - 0.43 10.6 7.2 0.48 10.5 7.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 OWF42653.1 - 0.44 8.4 4.8 0.44 8.4 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec20 PF03908.13 OWF42653.1 - 0.47 10.4 2.3 0.7 9.9 2.1 1.4 1 1 0 1 1 1 0 Sec20 Pup PF05639.11 OWF42653.1 - 0.71 10.8 0.2 0.71 10.8 0.2 3.3 1 1 2 3 3 3 0 Pup-like protein LMBR1 PF04791.16 OWF42653.1 - 1.2 7.9 2.5 1.3 7.8 2.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Proteasom_PSMB PF10508.9 OWF42654.1 - 0.11 11.0 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Suppressor_APC PF11414.8 OWF42656.1 - 4.5e-25 87.5 9.8 8.2e-25 86.7 7.0 2.5 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein Lipoprotein_6 PF01441.19 OWF42656.1 - 0.0046 17.0 0.4 0.011 15.7 0.4 1.6 1 0 0 1 1 1 1 Lipoprotein FliD_N PF02465.18 OWF42656.1 - 2.2 9.0 9.4 3.3 8.5 1.5 3.7 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus bZIP_1 PF00170.21 OWF42656.1 - 2.5 8.3 7.7 0.19 11.8 0.5 2.8 3 0 0 3 3 3 0 bZIP transcription factor APG6_N PF17675.1 OWF42656.1 - 3.3 8.3 11.8 16 6.0 5.9 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 OWF42656.1 - 7.7 6.6 10.1 0.39 10.8 0.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding zf-C2H2_jaz PF12171.8 OWF42657.1 - 8.9e-07 29.0 12.5 2.6e-05 24.4 2.9 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF42657.1 - 1.2e-06 28.7 9.5 0.00052 20.3 3.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OWF42657.1 - 0.059 13.7 8.9 0.069 13.5 2.6 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 OWF42657.1 - 0.079 12.6 1.3 0.17 11.5 1.3 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 OWF42657.1 - 7.6 7.2 8.7 2.7 8.6 1.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DHHC PF01529.20 OWF42658.1 - 2.8e-24 85.8 17.5 2.8e-24 85.8 17.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase YibE_F PF07907.11 OWF42658.1 - 4.4 6.7 18.3 4.6 6.7 9.7 2.1 2 0 0 2 2 2 0 YibE/F-like protein tRNA-synt_1 PF00133.22 OWF42659.1 - 2.9e-211 702.9 0.0 2.9e-211 702.9 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OWF42659.1 - 1.2e-38 132.4 0.0 3.6e-38 130.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OWF42659.1 - 4.6e-13 48.7 0.8 1.6e-05 23.9 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OWF42659.1 - 1.2e-10 41.2 11.8 6.3e-10 38.9 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 OWF42659.1 - 0.0018 18.5 1.1 0.0018 18.5 1.1 3.4 2 1 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 OWF42659.1 - 0.052 12.9 0.0 0.052 12.9 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain RES PF08808.11 OWF42659.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 RES domain BrnA_antitoxin PF14384.6 OWF42659.1 - 7.1 7.2 7.2 4.3 7.9 0.0 2.8 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system ABC2_membrane_3 PF12698.7 OWF42660.1 - 3.7e-60 203.8 55.1 6e-43 147.3 18.2 4.5 4 2 0 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.27 OWF42660.1 - 4.8e-56 189.1 0.0 4.2e-27 95.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OWF42660.1 - 2.2e-18 67.1 0.6 8.1e-07 29.1 0.0 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 OWF42660.1 - 0.00085 20.0 1.6 0.049 14.4 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) Zeta_toxin PF06414.12 OWF42660.1 - 0.0036 16.6 0.0 0.4 9.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 OWF42660.1 - 0.019 15.5 0.6 0.019 15.5 0.6 4.0 5 0 0 5 5 5 0 AAA domain SRP54 PF00448.22 OWF42660.1 - 0.039 13.6 1.8 7.7 6.1 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OWF42660.1 - 0.05 13.8 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 OWF42660.1 - 0.11 11.8 17.3 0.0061 15.9 11.0 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein MukB PF04310.12 OWF42660.1 - 0.16 11.8 0.5 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal AAA_29 PF13555.6 OWF42660.1 - 0.16 11.7 2.0 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Med13_C PF06333.12 OWF42660.1 - 2.2 7.5 6.8 2.5 7.3 0.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Ribosomal_L7Ae PF01248.26 OWF42661.1 - 1.3e-22 79.3 0.1 2.6e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Med22 PF06179.12 OWF42662.1 - 3.5e-31 107.5 2.5 4.5e-31 107.2 2.5 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex tRNA_bind_4 PF18490.1 OWF42662.1 - 0.0037 17.1 0.4 0.0053 16.5 0.4 1.2 1 0 0 1 1 1 1 tRNA-binding domain PsaD PF02531.16 OWF42662.1 - 0.053 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 PsaD Pkinase PF00069.25 OWF42663.1 - 2.3e-46 158.3 0.2 5.6e-46 157.0 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42663.1 - 1.1e-26 93.6 0.1 2.2e-26 92.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 OWF42663.1 - 1.4e-07 31.3 1.6 0.034 14.2 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 OWF42663.1 - 2.5e-07 30.3 0.1 1.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like HEAT_2 PF13646.6 OWF42663.1 - 0.00034 20.9 0.9 0.0045 17.3 0.0 2.9 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 OWF42663.1 - 0.0016 18.5 2.6 11 6.6 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Atx10homo_assoc PF09759.9 OWF42663.1 - 0.0024 17.9 1.0 3.4 7.8 0.0 4.6 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain FTA2 PF13095.6 OWF42663.1 - 0.0084 15.8 0.6 0.17 11.5 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OWF42663.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.29 OWF42664.1 - 5.2e-35 120.8 0.1 9.8e-35 119.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF42664.1 - 2.6e-24 85.7 0.8 7e-23 81.1 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 OWF42664.1 - 0.00016 21.1 0.1 0.00027 20.4 0.1 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 OWF42664.1 - 0.00078 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit P_C10 PF14974.6 OWF42665.1 - 3.8e-38 129.7 0.1 4.2e-38 129.6 0.1 1.0 1 0 0 1 1 1 1 Protein C10 eIF3g PF12353.8 OWF42666.1 - 1.9e-33 115.5 2.2 3.1e-33 114.8 2.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OWF42666.1 - 4.6e-20 71.2 0.0 8.8e-20 70.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF42666.1 - 0.003 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RNA_bind PF08675.11 OWF42666.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 OWF42666.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BNR_6 PF15899.5 OWF42669.1 - 0.0004 20.2 16.8 64 4.0 0.0 8.0 9 0 0 9 9 9 6 BNR-Asp box repeat DUF3288 PF11691.8 OWF42669.1 - 0.038 14.0 0.3 50 4.0 0.0 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF3288) PhyH PF05721.13 OWF42670.1 - 1.5e-19 71.1 0.0 3.1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) STAT_bind PF02864.15 OWF42671.1 - 7.4e-13 49.2 1.6 8.3e-13 49.0 0.1 1.9 2 0 0 2 2 2 1 STAT protein, DNA binding domain DUF3023 PF11224.8 OWF42671.1 - 0.0082 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3023) Laminin_I PF06008.14 OWF42671.1 - 0.0086 15.8 2.0 0.041 13.6 2.0 1.9 1 1 0 1 1 1 1 Laminin Domain I DUF4085 PF13315.6 OWF42671.1 - 0.046 13.3 1.8 0.13 11.9 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4085) DNA_Packaging PF11053.8 OWF42671.1 - 0.067 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Terminase DNA packaging enzyme DUF4404 PF14357.6 OWF42671.1 - 0.19 12.4 1.4 0.7 10.6 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Pro_isomerase PF00160.21 OWF42673.1 - 4.5e-51 173.2 0.1 5.2e-51 173.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cullin PF00888.22 OWF42674.1 - 2.8e-31 108.8 0.8 6.3e-31 107.7 0.8 1.5 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 OWF42674.1 - 2.6e-27 95.1 0.5 3.3e-25 88.4 0.1 3.9 4 0 0 4 4 4 1 Anaphase promoting complex (APC) subunit 2 GCV_T PF01571.21 OWF42674.1 - 0.027 13.9 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain FeoC PF09012.10 OWF42674.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator I-set PF07679.16 OWF42675.1 - 3.2e-86 283.5 0.5 7.6e-22 77.2 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF42675.1 - 1.5e-61 205.0 3.2 4e-15 56.2 0.0 6.6 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 OWF42675.1 - 3e-38 129.9 8.6 4.9e-10 39.4 0.1 5.6 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 OWF42675.1 - 3.5e-35 120.2 0.9 1.1e-09 38.5 0.0 5.2 4 0 0 4 4 4 4 Immunoglobulin domain Smoothelin PF12510.8 OWF42675.1 - 3.5e-27 94.2 24.6 3.3e-12 46.2 0.7 4.8 4 0 0 4 4 4 4 Smoothelin cytoskeleton protein CH PF00307.31 OWF42675.1 - 2e-20 73.0 0.3 4.8e-20 71.8 0.3 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain V-set PF07686.17 OWF42675.1 - 3.8e-13 49.6 16.5 0.034 14.3 0.2 8.8 5 4 0 5 5 5 4 Immunoglobulin V-set domain Ig_5 PF16681.5 OWF42675.1 - 4.7e-13 49.3 1.8 0.083 13.3 0.4 5.6 4 0 0 4 4 4 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 OWF42675.1 - 4.8e-08 33.2 8.6 0.13 12.5 0.0 5.4 5 0 0 5 5 4 3 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 OWF42675.1 - 9.9e-07 28.7 2.9 4.9 7.3 0.0 6.2 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 OWF42675.1 - 8.7e-06 25.2 0.0 0.91 9.1 0.0 4.3 4 0 0 4 4 4 1 Immunoglobulin domain CAMSAP_CH PF11971.8 OWF42675.1 - 0.00029 20.6 0.0 0.00072 19.3 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain Ig_C17orf99 PF17736.1 OWF42675.1 - 0.0044 17.0 0.0 32 4.6 0.0 4.0 4 0 0 4 4 4 0 C17orf99 Ig domain bZIP_1 PF00170.21 OWF42676.1 - 6e-07 29.5 11.7 6e-07 29.5 11.7 3.5 3 1 1 4 4 4 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF42676.1 - 1.8e-06 28.4 6.3 1.8e-06 28.4 6.3 4.5 5 1 0 5 5 5 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OWF42676.1 - 2.7e-06 27.3 10.5 2.7e-06 27.3 10.5 3.3 3 0 0 3 3 3 1 Basic region leucine zipper PDZ PF00595.24 OWF42676.1 - 0.00017 21.8 0.2 0.00057 20.2 0.0 2.0 2 0 0 2 2 1 1 PDZ domain PDZ_6 PF17820.1 OWF42676.1 - 0.00065 19.5 0.0 0.0087 15.9 0.0 2.6 2 0 0 2 2 2 1 PDZ domain RBD-FIP PF09457.10 OWF42676.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 3.4 4 0 0 4 4 4 1 FIP domain SAM_2 PF07647.17 OWF42676.1 - 0.0024 18.0 0.2 0.0076 16.3 0.2 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ZapB PF06005.12 OWF42676.1 - 0.035 14.6 0.9 0.035 14.6 0.9 3.8 4 0 0 4 4 4 0 Cell division protein ZapB YabA PF06156.13 OWF42676.1 - 0.04 14.5 1.0 0.04 14.5 1.0 3.7 3 0 0 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 OWF42676.1 - 1.2 9.3 26.3 1 9.5 5.5 4.2 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4110 PF13422.6 OWF42676.1 - 4.2 7.5 0.0 4.2 7.5 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4110) Ank_2 PF12796.7 OWF42677.1 - 2e-83 275.0 28.0 2.6e-12 47.2 3.2 12.0 3 3 10 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF42677.1 - 6.6e-64 211.5 23.9 6.7e-06 26.5 0.5 17.4 7 5 11 18 18 18 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF42677.1 - 1.6e-58 187.7 21.3 0.0014 18.9 0.0 21.0 23 0 0 23 23 23 13 Ankyrin repeat Ank_5 PF13857.6 OWF42677.1 - 6.7e-58 192.0 23.4 2.5e-06 27.6 0.1 16.0 7 4 11 18 18 18 13 Ankyrin repeats (many copies) Ank PF00023.30 OWF42677.1 - 9.1e-51 168.2 37.4 4.7e-06 26.8 0.2 20.2 20 0 0 20 20 20 12 Ankyrin repeat GLTP PF08718.11 OWF42677.1 - 2.8e-35 121.8 0.1 9.1e-35 120.1 0.0 2.0 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) BTB PF00651.31 OWF42677.1 - 6.3e-14 52.1 0.0 2e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain FYVE PF01363.21 OWF42677.1 - 2.2e-12 47.0 4.8 5.2e-12 45.7 4.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OWF42677.1 - 0.037 14.2 3.3 0.094 12.9 3.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Tantalus PF15386.6 OWF42678.1 - 9.5e-09 35.2 4.6 3.8e-08 33.3 4.6 2.0 1 0 0 1 1 1 1 Drosophila Tantalus-like PS_Dcarbxylase PF02666.15 OWF42679.1 - 8.7e-64 214.8 0.0 1.1e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Methyltransf_22 PF13383.6 OWF42680.1 - 1.5e-09 37.8 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 OWF42681.1 - 5.7e-104 348.4 0.0 6.9e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF42682.1 - 2.3e-103 346.4 0.1 2.7e-103 346.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 NYD-SP28 PF14772.6 OWF42683.1 - 1.9e-28 98.5 17.7 1.9e-28 98.5 17.7 5.2 3 1 3 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 OWF42683.1 - 9.9e-07 28.8 3.8 9.9e-07 28.8 3.8 5.4 5 1 1 6 6 6 2 Sperm tail C-terminal domain DASH_Dad1 PF08649.10 OWF42683.1 - 0.3 11.3 0.1 0.3 11.3 0.1 4.2 5 0 0 5 5 5 0 DASH complex subunit Dad1 Lectin_N PF03954.14 OWF42683.1 - 0.31 10.8 21.8 2.8 7.7 3.5 4.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Tweety PF04906.13 OWF42683.1 - 3.6 6.2 12.6 2 7.0 1.0 2.8 2 1 0 2 2 2 0 Tweety zf-C2H2_11 PF16622.5 OWF42684.1 - 0.023 14.5 0.4 0.65 9.8 0.0 3.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 OWF42684.1 - 0.069 14.0 11.4 1.2 10.2 0.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF42684.1 - 0.069 13.6 13.4 0.081 13.4 1.1 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 OWF42684.1 - 0.085 13.3 3.3 8.7 6.9 0.6 4.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF42684.1 - 0.11 12.6 3.8 0.35 10.9 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2175 PF09943.9 OWF42684.1 - 0.13 12.6 2.9 0.44 10.9 0.5 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Zn-C2H2_12 PF18112.1 OWF42684.1 - 1.4 9.4 6.9 16 6.1 2.8 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain C1_4 PF07975.12 OWF42684.1 - 2.3 8.5 8.3 0.66 10.2 3.1 3.1 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 OWF42684.1 - 4.7 7.6 8.0 0.61 10.4 2.9 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DAO PF01266.24 OWF42685.1 - 2.7e-48 165.4 0.0 3.1e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF42685.1 - 2.2e-05 24.6 1.1 0.00024 21.3 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OWF42685.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF42685.1 - 0.00023 20.5 0.1 0.052 12.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF42685.1 - 0.0013 18.0 0.0 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OWF42685.1 - 0.0034 16.5 0.0 0.006 15.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF42685.1 - 0.012 14.3 0.0 0.035 12.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 OWF42685.1 - 0.04 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OWF42685.1 - 0.17 11.1 0.0 6.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4298 PF14131.6 OWF42685.1 - 0.21 11.6 0.4 3.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) DAO PF01266.24 OWF42686.1 - 2.6e-07 30.6 0.1 2.7e-07 30.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ank_2 PF12796.7 OWF42687.1 - 3.3e-06 27.6 0.1 1e-05 26.0 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) ubiquitin PF00240.23 OWF42687.1 - 8.8e-05 22.2 0.0 0.27 11.0 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin family Ank_4 PF13637.6 OWF42687.1 - 0.00014 22.3 0.0 0.0073 16.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF4592 PF15262.6 OWF42687.1 - 0.77 10.4 7.1 0.16 12.6 3.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) DUF525 PF04379.14 OWF42688.1 - 3e-21 75.5 0.0 5.2e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 OWF42688.1 - 1.7e-06 28.5 0.2 4.4e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Ion_trans PF00520.31 OWF42689.1 - 5.4e-27 94.6 21.1 8e-27 94.0 21.1 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF42689.1 - 1.7e-15 57.1 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF42689.1 - 3.6e-11 42.9 6.8 3.6e-11 42.9 6.8 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 OWF42689.1 - 0.00078 19.5 0.1 0.002 18.2 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 OWF42691.1 - 1.6e-23 83.2 20.0 1.9e-23 83.0 20.0 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF42691.1 - 2e-12 46.9 6.8 2e-12 46.9 6.8 2.0 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 OWF42692.1 - 8.7e-23 80.8 17.1 1.2e-22 80.3 17.1 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF42692.1 - 5.3e-19 68.4 0.0 9.7e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF42692.1 - 3.7e-13 49.3 4.6 3.7e-13 49.3 4.6 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 OWF42692.1 - 0.0071 16.4 0.1 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF202 PF02656.15 OWF42692.1 - 6.6 7.3 10.3 1.4 9.4 0.8 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Ion_trans PF00520.31 OWF42693.1 - 6.5e-27 94.3 25.4 9e-27 93.9 25.4 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF42693.1 - 1.7e-18 66.8 0.0 3.2e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF42693.1 - 7.1e-12 45.1 11.7 7.1e-12 45.1 11.7 2.7 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 OWF42693.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Lig_chan PF00060.26 OWF42693.1 - 1.5 8.7 9.0 7.2 6.4 2.8 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel Astacin PF01400.24 OWF42694.1 - 1.4e-66 223.8 0.0 2.4e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 OWF42694.1 - 1.6e-18 67.2 0.0 3.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu CUB PF00431.20 OWF42694.1 - 2.4e-17 63.3 0.0 6e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 OWF42694.1 - 7e-12 45.4 24.5 1.2e-09 38.2 5.9 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain Sushi PF00084.20 OWF42694.1 - 9.9e-07 29.3 0.2 3.1e-06 27.7 0.2 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) CRAL_TRIO PF00650.20 OWF42695.1 - 5.7e-32 110.6 0.0 8.7e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 OWF42695.1 - 7.6e-13 49.1 0.1 6.2e-06 26.7 0.0 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 OWF42695.1 - 3.6e-05 23.8 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CRAL_TRIO_N PF03765.15 OWF42695.1 - 0.024 14.8 0.2 0.058 13.6 0.2 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain HAP2-GCS1 PF10699.9 OWF42695.1 - 0.058 13.4 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 Male gamete fusion factor Methyltransf_11 PF08241.12 OWF42696.1 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF42696.1 - 4.1e-18 65.9 0.0 6.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42696.1 - 3.1e-12 46.5 0.0 4.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF42696.1 - 5.3e-12 46.4 0.0 9.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF42696.1 - 1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF42696.1 - 1.4e-08 34.8 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF42696.1 - 0.00012 21.5 0.0 0.00027 20.3 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 OWF42696.1 - 0.0013 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 OWF42696.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.11 OWF42696.1 - 0.0087 15.7 0.0 0.053 13.2 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_15 PF09445.10 OWF42696.1 - 0.0091 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 OWF42696.1 - 0.0099 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OWF42696.1 - 0.011 15.2 0.0 0.058 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 OWF42696.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 OWF42696.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.11 OWF42696.1 - 0.036 13.1 0.0 0.087 11.8 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 OWF42696.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 OWF42697.1 - 1.5e-21 76.8 0.0 3.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF42697.1 - 2.5e-18 66.6 0.0 4.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF42697.1 - 2.1e-14 54.0 0.0 3.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42697.1 - 1.5e-13 50.8 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF42697.1 - 1.2e-09 37.9 0.0 3.1e-09 36.5 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF42697.1 - 4.2e-08 33.2 0.0 5.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF42697.1 - 1.4e-06 27.8 0.0 2.5e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 OWF42697.1 - 0.00054 19.9 0.0 0.0022 17.9 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.11 OWF42697.1 - 0.0021 17.8 0.0 0.0052 16.5 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OWF42697.1 - 0.0028 17.2 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OWF42697.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 OWF42697.1 - 0.036 13.5 0.0 0.58 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.10 OWF42697.1 - 0.042 13.4 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase 7tm_1 PF00001.21 OWF42698.1 - 2.6e-15 56.5 17.1 3.3e-15 56.1 17.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3128 PF11326.8 OWF42699.1 - 0.00025 21.3 7.2 0.00025 21.3 7.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3128) Cdh1_DBD_1 PF18196.1 OWF42699.1 - 0.032 14.5 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 NO_synthase PF02898.15 OWF42701.1 - 1.7e-184 612.9 0.0 2.4e-184 612.5 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 OWF42701.1 - 1.7e-60 204.4 0.0 2.9e-60 203.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OWF42701.1 - 6.7e-48 162.5 0.3 4.2e-47 159.9 0.3 2.3 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OWF42701.1 - 1.6e-17 64.1 0.0 4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PDZ PF00595.24 OWF42701.1 - 1.3e-09 38.2 0.0 5.4e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 OWF42701.1 - 8.1e-06 25.6 0.3 2e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 PDZ domain GlcV_C_terminal PF17847.1 OWF42702.1 - 0.0019 18.6 2.8 51 4.4 0.0 6.0 1 1 5 7 7 7 0 Glucose ABC transporter C-terminal domain TraI PF07057.11 OWF42702.1 - 0.017 15.2 5.9 17 5.6 0.1 4.5 1 1 5 6 6 6 0 DNA helicase TraI GrpB PF04229.14 OWF42702.1 - 0.028 14.6 0.0 30 4.7 0.0 3.6 1 1 3 4 4 4 0 GrpB protein XRN1_D1 PF18332.1 OWF42702.1 - 0.055 13.2 0.0 4.6 7.0 0.1 2.9 1 1 1 2 2 2 0 Exoribonuclease Xrn1 D1 domain CCB2_CCB4 PF11152.8 OWF42702.1 - 0.13 11.5 2.3 6.7 6.0 0.0 3.7 1 1 1 3 3 3 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 ABC_trans_aux PF03886.13 OWF42702.1 - 0.52 9.9 8.6 6.6 6.3 1.2 3.5 1 1 2 3 3 3 0 ABC-type transport auxiliary lipoprotein component Cucumopine_C PF18631.1 OWF42702.1 - 1.1 9.2 7.4 19 5.2 0.0 5.2 3 2 4 7 7 7 0 Cucumopine synthase C-terminal helical bundle domain Fer4_11 PF13247.6 OWF42703.1 - 0.088 12.9 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trypsin PF00089.26 OWF42704.1 - 2.9e-61 207.1 0.9 3.3e-61 206.9 0.9 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF42704.1 - 6.2e-07 30.4 0.1 1.1e-06 29.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 OWF42704.1 - 0.0068 16.0 0.0 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 DUF3290 PF11694.8 OWF42705.1 - 0.096 12.7 0.3 0.24 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) HNH_repeat PF18780.1 OWF42705.1 - 0.87 9.5 3.5 1.4 8.8 3.5 1.4 1 0 0 1 1 1 0 Homing endonuclease repeat GTF2I PF02946.14 OWF42707.1 - 1.7e-05 24.8 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 GTF2I-like repeat EF-hand_7 PF13499.6 OWF42708.1 - 1.3e-11 44.8 4.2 3.7e-11 43.3 0.8 5.7 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF42708.1 - 2.2e-09 37.0 1.5 3.3e-07 30.1 0.8 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF42708.1 - 5.8e-08 31.7 0.0 4.3e-05 22.8 0.1 4.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OWF42708.1 - 8.2e-08 31.6 0.0 0.00012 21.7 0.0 4.1 3 0 0 3 3 3 1 EF-hand domain Apolipoprotein PF01442.18 OWF42708.1 - 7.2e-06 26.0 55.5 0.00012 22.1 24.2 8.4 3 2 4 8 8 8 3 Apolipoprotein A1/A4/E domain EF-hand_5 PF13202.6 OWF42708.1 - 0.00049 19.5 0.3 0.0022 17.4 0.3 2.2 1 0 0 1 1 1 1 EF hand DUF3452 PF11934.8 OWF42708.1 - 0.015 14.9 0.1 0.015 14.9 0.1 6.1 6 1 0 6 6 6 0 Domain of unknown function (DUF3452) EF-hand_9 PF14658.6 OWF42708.1 - 0.22 11.9 2.4 1.3 9.4 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain Strep_SA_rep PF06696.11 OWF42708.1 - 0.32 11.0 4.9 1.1 9.3 0.0 4.5 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Fibrinogen_BP PF08017.11 OWF42709.1 - 2.9e-09 35.8 0.0 8.3e-05 21.2 0.0 2.0 1 1 0 1 1 1 1 Fibrinogen binding protein EB PF01683.18 OWF42710.1 - 0.47 10.8 10.2 0.66 10.3 10.2 1.3 1 0 0 1 1 1 0 EB module PEPCK_GTP PF00821.18 OWF42711.1 - 0.02 13.7 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Myb_DNA-bind_7 PF15963.5 OWF42711.1 - 0.031 14.2 0.3 0.11 12.4 0.3 1.9 1 0 0 1 1 1 0 Myb DNA-binding like MAPEG PF01124.18 OWF42712.1 - 6.6e-24 84.3 1.4 8.2e-24 84.0 1.4 1.1 1 0 0 1 1 1 1 MAPEG family Tetraspanin PF00335.20 OWF42712.1 - 0.78 9.4 3.1 1.2 8.8 2.0 1.7 2 0 0 2 2 2 0 Tetraspanin family MOLO1 PF17175.4 OWF42713.1 - 7.4e-26 90.6 0.2 1.2e-25 89.9 0.2 1.4 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 OWF42713.1 - 0.00069 19.8 0.5 0.034 14.3 0.5 2.3 1 1 0 1 1 1 1 TPM domain Copine PF07002.16 OWF42713.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Copine SRCR PF00530.18 OWF42714.1 - 2.7e-154 502.7 49.0 7.3e-28 97.0 0.5 6.8 7 0 0 7 7 7 6 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF42714.1 - 3.7e-28 97.9 14.3 0.00037 21.0 0.3 6.7 6 0 0 6 6 6 6 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF42714.1 - 1.7e-11 44.6 0.6 0.57 10.7 0.2 6.4 6 0 0 6 6 6 3 Hepsin, SRCR domain SapB_2 PF03489.17 OWF42714.1 - 0.0022 18.1 1.5 57 4.0 0.0 6.1 8 0 0 8 8 8 0 Saposin-like type B, region 2 Gal-3-0_sulfotr PF06990.11 OWF42716.1 - 1.1e-37 129.8 0.2 1.5e-37 129.4 0.2 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase YhzD PF14120.6 OWF42717.1 - 1.3e-05 25.2 11.2 49 4.1 0.0 12.3 13 4 1 14 14 14 2 YhzD-like protein G_glu_transpept PF01019.21 OWF42718.1 - 5.2e-154 513.8 1.4 6.2e-154 513.5 1.4 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cluap1 PF10234.9 OWF42718.1 - 0.027 13.9 0.4 0.042 13.2 0.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 7tm_1 PF00001.21 OWF42719.1 - 6.2e-80 268.3 2.4 1.3e-79 267.2 2.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF42719.1 - 2.5e-06 27.0 13.5 4.4e-05 23.0 5.5 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF42719.1 - 0.00061 19.6 15.9 0.0047 16.7 10.5 2.9 2 1 0 2 2 2 1 Olfactory receptor MscS_TM PF12794.7 OWF42719.1 - 0.046 12.6 9.1 0.16 10.8 0.0 3.0 3 1 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Coiled-coil_56 PF09813.9 OWF42719.1 - 0.13 12.4 1.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 FA_desaturase PF00487.24 OWF42719.1 - 0.56 10.0 0.0 0.56 10.0 0.0 2.4 2 1 1 3 3 3 0 Fatty acid desaturase S1FA PF04689.13 OWF42719.1 - 8.4 6.6 11.3 15 5.8 1.4 3.4 3 0 0 3 3 3 0 DNA binding protein S1FA Exonuc_VII_L PF02601.15 OWF42720.1 - 0.0013 18.4 15.6 0.021 14.4 2.6 2.5 2 0 0 2 2 2 2 Exonuclease VII, large subunit IFT57 PF10498.9 OWF42720.1 - 0.01 14.8 24.2 0.011 14.8 9.5 3.3 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF4200 PF13863.6 OWF42720.1 - 0.14 12.6 26.2 0.19 12.2 9.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HMMR_N PF15905.5 OWF42720.1 - 1.4 8.3 30.7 1 8.8 10.6 2.9 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4618 PF15397.6 OWF42720.1 - 3.3 7.0 29.1 12 5.3 11.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 OWF42720.1 - 4.5 6.5 15.9 0.31 10.4 8.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 OWF42720.1 - 7.6 6.3 9.8 0.39 10.5 0.5 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 OWF42720.1 - 9.2 5.0 33.7 3.8 6.3 2.0 3.4 2 2 2 4 4 4 0 Spc7 kinetochore protein Insulin_TMD PF17870.1 OWF42721.1 - 0.2 11.7 3.5 19 5.4 2.1 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment AAA_12 PF13087.6 OWF42722.1 - 1.3e-39 135.9 0.0 2.7e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OWF42722.1 - 8.5e-34 117.5 0.3 1.9e-32 113.1 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF42722.1 - 1.1e-08 35.5 0.2 5.4e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OWF42722.1 - 1.6e-06 28.0 0.1 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 OWF42722.1 - 0.00097 18.5 0.1 0.017 14.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OWF42722.1 - 0.0017 18.0 1.0 0.0097 15.5 1.0 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 OWF42722.1 - 0.0056 16.2 0.1 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 OWF42722.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 OWF42722.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF42722.1 - 0.013 15.8 0.1 0.065 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OWF42722.1 - 0.029 14.1 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 OWF42722.1 - 0.073 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OWF42722.1 - 0.08 13.4 0.1 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Exonuc_VII_L PF02601.15 OWF42722.1 - 1.7 8.1 3.4 0.76 9.3 0.1 2.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit GDA1_CD39 PF01150.17 OWF42723.1 - 5.3e-120 400.9 0.0 7.3e-120 400.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Baculo_11_kDa PF06143.11 OWF42723.1 - 0.1 12.2 2.5 0.13 11.9 0.3 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family SecE PF00584.20 OWF42723.1 - 0.93 9.5 6.6 0.23 11.4 0.6 2.3 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex zf-H2C2_2 PF13465.6 OWF42724.1 - 1.8e-77 252.6 164.9 4.5e-09 36.3 1.6 24.3 24 0 0 24 24 24 17 Zinc-finger double domain zf-C2H2 PF00096.26 OWF42724.1 - 8.9e-70 227.5 196.9 1e-05 25.7 2.5 22.6 22 0 0 22 22 22 21 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF42724.1 - 1.1e-55 181.5 181.8 0.00055 20.5 1.6 22.6 22 0 0 22 22 22 22 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF42724.1 - 4.6e-14 52.3 146.3 0.059 13.7 0.2 22.0 23 0 0 23 23 23 12 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF42724.1 - 1.3e-12 47.4 145.1 0.015 15.3 1.1 19.9 19 0 0 19 19 19 10 C2H2-type zinc finger zf-met PF12874.7 OWF42724.1 - 2.8e-10 40.2 134.2 0.029 14.7 0.5 19.9 22 0 0 22 22 21 11 Zinc-finger of C2H2 type TRAF6_Z2 PF18048.1 OWF42724.1 - 6.3e-06 26.2 0.8 6.3e-06 26.2 0.8 9.4 12 1 1 13 13 13 1 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_11 PF16622.5 OWF42724.1 - 1.9e-05 24.3 9.9 0.0053 16.5 0.8 15.8 19 0 0 19 19 18 6 zinc-finger C2H2-type GAGA PF09237.11 OWF42724.1 - 0.022 14.6 20.3 2.9 7.8 0.5 8.2 8 2 2 10 10 10 0 GAGA factor zf-C2HE PF16278.5 OWF42724.1 - 0.095 13.2 0.1 0.095 13.2 0.1 15.2 10 3 4 14 14 13 0 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 OWF42724.1 - 0.23 11.8 30.1 4.6 7.6 0.1 9.8 6 3 4 10 10 10 0 BolA-like protein zf-C2HC_2 PF13913.6 OWF42724.1 - 0.74 9.8 90.4 0.38 10.7 1.3 15.6 17 0 0 17 17 16 0 zinc-finger of a C2HC-type Ank_2 PF12796.7 OWF42725.1 - 8.7e-56 186.5 45.4 3.5e-05 24.3 0.1 16.0 2 1 14 16 16 16 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF42725.1 - 3.9e-41 138.9 48.3 0.071 13.7 0.1 20.8 16 12 13 29 29 29 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF42725.1 - 1e-29 102.2 23.6 1.3 9.4 0.0 20.1 17 6 6 23 23 23 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF42725.1 - 4.7e-17 60.3 28.6 8.5 7.3 0.0 22.1 26 0 0 26 26 26 1 Ankyrin repeat NTP_transf_2 PF01909.23 OWF42725.1 - 2.8e-14 53.2 0.2 85 3.5 0.0 12.4 13 0 0 13 13 13 0 Nucleotidyltransferase domain Ank PF00023.30 OWF42725.1 - 9.8e-07 29.0 18.3 1.9e+02 2.7 0.0 15.7 17 0 0 17 17 17 0 Ankyrin repeat Poxvirus_B22R_C PF13168.6 OWF42725.1 - 0.0056 16.2 18.8 2.9 7.3 0.0 9.7 10 2 1 12 12 12 1 Poxvirus B22R protein C-terminal BOFC_N PF08977.10 OWF42725.1 - 0.017 15.1 0.4 5.9 7.0 0.0 4.3 3 0 0 3 3 3 0 Bypass of Forespore C, N terminal Oxidored-like PF09791.9 OWF42725.1 - 0.15 11.8 0.2 0.7 9.6 0.1 2.2 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal Flavi_glycop_C PF02832.16 OWF42727.1 - 0.003 17.7 7.0 3.9 7.7 0.0 6.1 1 1 6 8 8 8 1 Flavivirus glycoprotein, immunoglobulin-like domain ARGLU PF15346.6 OWF42727.1 - 0.018 15.0 38.0 0.13 12.2 3.9 4.8 1 1 3 4 4 4 0 Arginine and glutamate-rich 1 SspH PF08141.12 OWF42730.1 - 1.1e-05 25.5 1.4 40 4.4 0.0 8.3 7 6 1 9 9 9 0 Small acid-soluble spore protein H family Glu_cyclase_2 PF05096.12 OWF42730.1 - 5.7e-05 22.7 1.2 1.1 8.6 0.1 3.8 1 1 2 4 4 4 2 Glutamine cyclotransferase Rib PF08428.10 OWF42730.1 - 0.00019 21.3 9.1 7.9 6.5 0.1 7.8 2 2 5 7 7 7 1 Rib/alpha-like repeat Pentapeptide_3 PF13576.6 OWF42730.1 - 0.00082 19.5 0.0 1.7 8.9 0.0 4.7 4 2 0 4 4 4 1 Pentapeptide repeats (9 copies) CBM_26 PF16824.5 OWF42730.1 - 0.01 16.0 2.1 43 4.2 0.1 5.7 2 1 3 6 6 6 0 C-terminal carbohydrate-binding module Spo0A_C PF08769.11 OWF42730.1 - 0.083 13.0 0.3 1.2e+02 2.8 0.0 4.9 6 1 1 7 7 7 0 Sporulation initiation factor Spo0A C terminal Fibrinogen_BP PF08017.11 OWF42730.1 - 0.17 10.3 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein GhoS PF11080.8 OWF42730.1 - 0.24 11.4 11.3 8.4 6.4 0.8 5.0 1 1 3 4 4 4 0 Endoribonuclease GhoS DUF3634 PF12321.8 OWF42730.1 - 0.77 10.2 8.6 1.4e+02 2.9 0.0 6.0 2 2 5 8 8 8 0 Protein of unknown function (DUF3634) STT3 PF02516.14 OWF42730.1 - 1.7 7.5 6.1 44 2.8 0.1 4.7 2 2 3 6 6 6 0 Oligosaccharyl transferase STT3 subunit Phage_spike PF18715.1 OWF42731.1 - 0.0014 18.6 2.6 30 4.8 0.1 5.2 5 0 0 5 5 5 1 Phage spike trimer APOBEC1 PF18769.1 OWF42731.1 - 0.0032 17.7 5.3 0.32 11.3 0.1 3.2 1 1 2 3 3 3 2 APOBEC1 LBP_C PF17386.2 OWF42731.1 - 0.023 14.6 42.7 7.7 6.5 0.2 11.1 9 2 3 12 12 12 0 Lacto-N-biose phosphorylase C-terminal domain Glyco_hydro_32C PF08244.12 OWF42732.1 - 0.00022 21.3 2.2 2.9 7.8 2.2 5.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Beta_helix_2 PF18835.1 OWF42732.1 - 0.00089 19.0 1.7 22 4.9 0.0 4.7 3 2 2 5 5 5 2 Beta helix repeat of Inulin fructotransferase DUF951 PF06107.11 OWF42732.1 - 0.0033 17.3 6.8 23 5.0 0.0 6.1 3 2 5 9 9 9 1 Bacterial protein of unknown function (DUF951) DUF4722 PF15849.5 OWF42732.1 - 0.046 13.4 0.8 6.1 6.5 0.1 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4722) LBP_C PF17386.2 OWF42732.1 - 0.26 11.2 34.3 17 5.4 0.1 9.1 5 4 5 10 10 10 0 Lacto-N-biose phosphorylase C-terminal domain Glyco_hydro_32C PF08244.12 OWF42733.1 - 0.00069 19.6 1.2 1 9.4 1.2 4.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4506 PF14958.6 OWF42733.1 - 0.00093 18.7 0.5 2.4 7.7 0.0 3.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4506) DUF951 PF06107.11 OWF42733.1 - 0.0083 16.0 5.8 13 5.7 0.1 4.6 2 2 1 5 5 5 2 Bacterial protein of unknown function (DUF951) Beta_helix_2 PF18835.1 OWF42733.1 - 0.024 14.4 0.5 5.1 6.9 0.0 3.6 2 2 2 4 4 4 0 Beta helix repeat of Inulin fructotransferase DUF2220 PF09983.9 OWF42733.1 - 2.9 7.2 6.3 41 3.5 0.0 4.2 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) LBP_C PF17386.2 OWF42733.1 - 3.8 7.5 27.1 10 6.1 0.1 7.4 5 1 4 9 9 9 0 Lacto-N-biose phosphorylase C-terminal domain Flu_C_NS1 PF03506.13 OWF42733.1 - 4.4 7.3 6.4 6.7 6.7 0.3 2.9 1 1 2 3 3 3 0 Influenza C non-structural protein (NS1) DUF1175 PF06672.11 OWF42733.1 - 4.9 6.8 6.6 13 5.4 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1175) Glyco_hydro_32C PF08244.12 OWF42734.1 - 1.4e-07 31.6 4.3 15 5.5 4.3 7.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Beta_helix_2 PF18835.1 OWF42734.1 - 0.00011 21.9 2.3 1.3 8.8 0.0 6.3 4 1 4 8 8 8 1 Beta helix repeat of Inulin fructotransferase LBP_C PF17386.2 OWF42734.1 - 0.0043 16.9 62.8 8 6.4 0.1 16.7 12 3 7 19 19 19 5 Lacto-N-biose phosphorylase C-terminal domain PapA_C PF16911.5 OWF42734.1 - 0.08 13.0 0.6 5.6 7.1 0.0 3.8 2 2 1 3 3 3 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus Cloacin PF03515.14 OWF42734.1 - 0.84 9.3 4.1 90 2.6 0.0 4.2 3 1 2 5 5 5 0 Colicin-like bacteriocin tRNase domain VWC PF00093.18 OWF42735.1 - 2.2e-23 82.3 90.8 4.1e-12 46.2 17.8 10.1 7 2 2 9 9 6 5 von Willebrand factor type C domain EGF_CA PF07645.15 OWF42735.1 - 2.8e-23 81.8 77.5 1.6e-08 34.6 7.7 11.0 10 1 1 11 11 6 5 Calcium-binding EGF domain EGF_3 PF12947.7 OWF42735.1 - 4.2e-15 55.7 47.1 3.4e-09 36.7 15.4 12.4 11 2 2 13 13 10 5 EGF domain Laminin_G_3 PF13385.6 OWF42735.1 - 1.4e-10 41.5 0.0 2.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 OWF42735.1 - 1.1e-07 32.1 39.1 0.00013 22.2 10.4 12.6 13 2 0 13 13 7 5 EGF-like domain cEGF PF12662.7 OWF42735.1 - 7.8e-07 28.9 11.8 3.7e-05 23.6 5.2 11.7 11 1 0 11 11 9 4 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 OWF42735.1 - 2.1e-06 27.7 18.8 2.6e-05 24.2 4.2 9.5 10 1 0 10 10 9 4 MSP1 EGF domain 1 Laminin_G_2 PF02210.24 OWF42735.1 - 1.3e-05 25.8 0.1 2.2e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain TILa PF12714.7 OWF42735.1 - 0.00064 19.6 12.6 0.00064 19.6 12.6 11.2 7 2 3 10 10 8 3 TILa domain hEGF PF12661.7 OWF42735.1 - 0.00072 20.1 21.0 0.0011 19.5 7.2 13.6 13 1 1 14 14 13 6 Human growth factor-like EGF FXa_inhibition PF14670.6 OWF42735.1 - 0.0016 18.7 1.4 0.0016 18.7 1.4 11.3 9 2 1 10 10 6 3 Coagulation Factor Xa inhibitory site Laminin_G_1 PF00054.23 OWF42735.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain CFC PF09443.10 OWF42735.1 - 0.007 16.2 3.2 0.007 16.2 3.2 8.6 9 0 0 9 9 9 4 Cripto_Frl-1_Cryptic (CFC) Plasmod_Pvs28 PF06247.11 OWF42735.1 - 0.036 14.4 0.8 0.036 14.4 0.8 10.0 7 2 2 9 9 8 0 Pvs28 EGF domain FdtA PF05523.11 OWF42735.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 WxcM-like, C-terminal SHIPPO-rpt PF07004.12 OWF42736.1 - 2.1e-10 41.0 31.5 4.3e-06 27.4 0.8 6.9 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat DEP PF00610.21 OWF42737.1 - 3.3e-16 59.1 0.1 1e-15 57.5 0.1 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF148 PF02520.17 OWF42737.1 - 0.042 13.9 1.1 0.082 13.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 BIR PF00653.21 OWF42738.1 - 1.2e-23 83.5 5.9 1.8e-23 83.0 5.9 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Tcp11 PF05794.13 OWF42739.1 - 1.1e-99 334.5 3.5 1.3e-99 334.3 3.5 1.0 1 0 0 1 1 1 1 T-complex protein 11 KDGP_aldolase PF07071.11 OWF42739.1 - 0.041 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 KDGP aldolase DUF1825 PF08855.10 OWF42739.1 - 0.29 11.1 3.1 0.73 9.8 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) WD40 PF00400.32 OWF42740.1 - 1.2e-36 124.0 7.4 6e-08 33.2 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40_like PF17005.5 OWF42740.1 - 1.6e-09 37.6 0.1 0.0021 17.4 0.0 3.2 2 1 0 2 2 2 2 WD40-like domain F-box-like PF12937.7 OWF42740.1 - 6.7e-09 35.5 0.2 1.3e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF42740.1 - 3e-07 30.1 0.1 6.1e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OWF42740.1 - 4.4e-07 28.9 8.6 0.3 9.7 0.2 4.6 4 1 0 4 4 4 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OWF42740.1 - 5.8e-07 29.7 1.2 0.75 10.1 0.0 4.8 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4508 PF14969.6 OWF42740.1 - 6.2e-06 26.4 2.2 0.072 13.3 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) DUF3394 PF11874.8 OWF42740.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Beta-TrCP_D PF12125.8 OWF42740.1 - 0.72 9.8 7.9 6.8 6.7 2.6 2.4 2 0 0 2 2 2 0 D domain of beta-TrCP Actin PF00022.19 OWF42741.1 - 2.6e-87 293.1 0.0 6.2e-86 288.6 0.0 2.0 1 1 0 1 1 1 1 Actin DUF5021 PF16424.5 OWF42741.1 - 0.087 12.7 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5021) Ctf8 PF09696.10 OWF42742.1 - 2.9e-12 47.1 0.1 2.4e-11 44.2 0.0 1.9 1 1 1 2 2 2 1 Ctf8 SAP18 PF06487.12 OWF42743.1 - 5.4e-41 140.0 0.0 7.2e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) TMEM154 PF15102.6 OWF42744.1 - 0.00019 21.4 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF3552 PF12072.8 OWF42744.1 - 0.00094 18.6 10.9 0.00094 18.6 10.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) FAM163 PF15069.6 OWF42744.1 - 0.0052 17.3 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 FAM163 family Tetraspanin PF00335.20 OWF42744.1 - 0.013 15.3 0.8 7.4 6.2 2.3 2.5 2 0 0 2 2 2 0 Tetraspanin family EphA2_TM PF14575.6 OWF42744.1 - 0.018 15.9 1.2 0.031 15.1 0.0 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 OWF42744.1 - 0.022 14.7 0.1 0.063 13.2 0.1 1.8 1 0 0 1 1 1 0 Transmembrane 52 RIFIN PF02009.16 OWF42744.1 - 0.051 13.5 0.8 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Rifin ECSCR PF15820.5 OWF42744.1 - 0.067 13.0 0.8 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Baculo_11_kDa PF06143.11 OWF42744.1 - 0.089 12.4 0.5 0.23 11.0 0.5 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family MFS_Mycoplasma PF07672.13 OWF42744.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter SieB PF14163.6 OWF42744.1 - 0.13 11.7 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 Super-infection exclusion protein B Spc7 PF08317.11 OWF42744.1 - 0.34 9.8 6.2 0.55 9.0 6.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3827 PF12877.7 OWF42744.1 - 0.85 7.9 5.9 0.087 11.2 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Tmemb_9 PF05434.11 OWF42744.1 - 1.1 9.2 6.2 0.067 13.1 0.7 1.7 2 0 0 2 2 2 0 TMEM9 DUF4446 PF14584.6 OWF42744.1 - 1.4 8.9 6.7 0.75 9.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) WD40 PF00400.32 OWF42746.1 - 1.1e-08 35.5 0.9 0.0019 19.0 0.0 4.6 5 1 0 5 5 5 3 WD domain, G-beta repeat Adeno_E1A PF02703.14 OWF42746.1 - 0.049 13.2 0.0 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Early E1A protein BIR PF00653.21 OWF42747.1 - 4.7e-07 30.4 1.1 2e-06 28.4 1.1 2.1 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain DUF643 PF04867.12 OWF42747.1 - 0.026 15.1 1.4 13 6.5 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Mito_carr PF00153.27 OWF42748.1 - 1.9e-68 226.4 2.1 1.4e-23 82.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SDF PF00375.18 OWF42748.1 - 0.014 14.4 0.0 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 Sodium:dicarboxylate symporter family DEAD PF00270.29 OWF42749.1 - 2.4e-45 154.5 0.1 5.3e-45 153.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF42749.1 - 2.5e-23 82.5 0.0 1.4e-22 80.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OWF42749.1 - 2.3e-16 59.7 0.1 7.1e-16 58.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OWF42749.1 - 2e-06 27.9 2.5 3.9e-06 27.0 0.0 2.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF5482 PF17579.2 OWF42749.1 - 0.00093 19.1 0.1 0.0024 17.7 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5482) HLH PF00010.26 OWF42750.1 - 7.6e-18 64.2 1.2 1.3e-17 63.4 1.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5340 PF17275.2 OWF42750.1 - 0.44 10.7 1.4 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5340) p450 PF00067.22 OWF42751.1 - 7.8e-103 344.7 0.0 9e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BIR PF00653.21 OWF42752.1 - 1e-38 131.8 2.5 2.1e-21 76.4 0.3 3.5 4 0 0 4 4 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF42752.1 - 1.7e-12 47.0 14.3 1.7e-12 47.0 14.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF42752.1 - 9.8e-06 25.3 13.6 3.1e-05 23.7 13.6 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF42752.1 - 0.015 15.6 17.0 0.015 15.6 17.0 2.6 2 0 0 2 2 2 0 Ring finger domain Nab2p_Zf1 PF18260.1 OWF42752.1 - 0.027 14.4 2.0 0.073 13.0 2.0 1.7 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 RuvA_C PF07499.13 OWF42752.1 - 0.035 14.6 0.0 1.2 9.7 0.0 2.7 3 0 0 3 3 3 0 RuvA, C-terminal domain Plant_NMP1 PF06694.11 OWF42752.1 - 0.047 12.8 0.0 0.096 11.8 0.0 1.4 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) zf-RING_11 PF17123.5 OWF42752.1 - 0.056 13.2 6.8 0.81 9.5 3.6 2.9 2 0 0 2 2 2 0 RING-like zinc finger Cnn_1N PF07989.11 OWF42752.1 - 0.098 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 UBA_6 PF18039.1 OWF42752.1 - 0.11 12.4 0.5 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain zf-RING_5 PF14634.6 OWF42752.1 - 1.9 8.5 20.6 0.32 11.0 15.4 2.4 3 0 0 3 3 3 0 zinc-RING finger domain DGCR6 PF07324.11 OWF42753.1 - 1.5e-78 262.9 14.7 1.7e-78 262.7 14.7 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 OWF42753.1 - 2.8e-06 27.1 4.7 2.8e-06 27.1 4.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) GST_C_2 PF13410.6 OWF42754.1 - 1.5e-10 40.9 0.0 2.7e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF42754.1 - 6.3e-09 36.0 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF42754.1 - 7.8e-06 26.0 0.1 1.2e-05 25.5 0.1 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF42754.1 - 0.0051 17.0 0.0 0.008 16.4 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF42755.1 - 1.9e-22 79.3 0.0 3.9e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF42755.1 - 5.2e-14 52.0 0.0 8.6e-12 44.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF42755.1 - 2e-07 31.1 0.0 3.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF42755.1 - 0.00049 20.5 0.1 0.0068 16.8 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF42755.1 - 0.00057 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OWF42755.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Phyto_Pns9_10 PF05878.11 OWF42755.1 - 0.081 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 UPF0728 PF15092.6 OWF42756.1 - 0.085 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 IF2_assoc PF08364.11 OWF42756.1 - 0.14 12.4 0.8 0.29 11.4 0.8 1.5 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region BIR PF00653.21 OWF42757.1 - 2.5e-29 101.7 17.3 2.1e-17 63.5 0.2 3.8 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF42757.1 - 5.7e-10 38.9 19.1 2.1e-09 37.1 19.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF42757.1 - 0.62 10.1 20.4 2.4 8.2 20.4 2.2 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF42757.1 - 0.63 10.0 18.1 2 8.4 18.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MutS_V PF00488.21 OWF42758.1 - 2.1e-83 279.0 0.3 4.5e-83 277.9 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OWF42758.1 - 3.3e-38 131.8 2.4 3.3e-38 131.8 2.4 2.5 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 OWF42758.1 - 3.3e-20 72.8 0.6 4.1e-19 69.2 0.1 2.8 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 OWF42758.1 - 5.9e-20 71.4 1.4 1.8e-19 69.9 1.4 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 OWF42758.1 - 2.3e-16 60.0 0.0 5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 OWF42758.1 - 0.0052 16.4 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain SCP-1 PF05483.12 OWF42759.1 - 6.8e-22 77.3 145.2 5.2e-19 67.8 145.2 3.9 1 1 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) AAA_13 PF13166.6 OWF42759.1 - 7e-07 28.3 33.5 7e-07 28.3 33.5 5.0 1 1 3 5 5 5 1 AAA domain CALCOCO1 PF07888.11 OWF42759.1 - 0.0028 16.6 24.7 0.0028 16.6 24.7 5.0 2 2 2 4 4 4 1 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.21 OWF42759.1 - 0.0076 15.9 1.3 0.0076 15.9 1.3 7.1 1 1 5 6 6 6 4 Intermediate filament protein SlyX PF04102.12 OWF42759.1 - 0.01 16.4 0.1 0.01 16.4 0.1 11.9 6 3 5 12 12 12 0 SlyX Glyco_hydro_38 PF18438.1 OWF42759.1 - 0.015 15.3 1.2 0.15 12.1 0.0 3.4 2 1 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 Gal4_dimer PF03902.13 OWF42759.1 - 1.1 9.5 8.2 3.5 7.9 0.4 4.1 3 0 0 3 3 3 0 Gal4-like dimerisation domain ATG16 PF08614.11 OWF42759.1 - 1.2 9.3 153.7 0.1 12.8 10.3 10.0 2 2 7 9 9 9 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OWF42759.1 - 6.2 7.2 153.2 0.018 15.5 12.0 8.4 2 1 6 8 8 8 0 Fez1 Herpes_BLLF1 PF05109.13 OWF42759.1 - 6.9 4.5 14.1 9.8 4.0 14.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-C4 PF00105.18 OWF42760.1 - 1.1e-28 99.5 15.7 2e-28 98.7 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF42760.1 - 2.4e-28 99.1 0.0 4.3e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Hormone_recep PF00104.30 OWF42761.1 - 1.6e-28 99.7 0.0 2.1e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF42761.1 - 1.1e-27 96.2 14.0 1.9e-27 95.5 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GluR_Homer-bdg PF10606.9 OWF42761.1 - 0.12 12.5 2.5 1.5 9.0 0.4 3.4 4 0 0 4 4 4 0 Homer-binding domain of metabotropic glutamate receptor WSC PF01822.19 OWF42762.1 - 0.026 14.7 8.9 0.078 13.2 8.9 1.9 1 0 0 1 1 1 0 WSC domain Ion_trans PF00520.31 OWF42763.1 - 4.1e-53 180.1 46.6 2.2e-28 99.2 24.2 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 OWF42763.1 - 0.00017 20.4 49.4 0.00093 18.0 11.0 5.9 3 2 1 5 5 5 4 Polycystin cation channel DUF5113 PF17140.4 OWF42763.1 - 0.015 15.1 1.4 0.028 14.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Cytadhesin_P30 PF07271.11 OWF42764.1 - 0.0023 17.6 37.7 0.46 10.0 9.8 3.1 1 1 2 3 3 3 3 Cytadhesin P30/P32 DUF1983 PF09327.11 OWF42765.1 - 0.055 13.5 3.8 1.7e+02 2.3 0.1 6.1 1 1 3 7 7 7 0 Domain of unknown function (DUF1983) Cytadhesin_P30 PF07271.11 OWF42765.1 - 2.6 7.5 54.4 6.1 6.3 8.9 5.5 1 1 4 5 5 5 0 Cytadhesin P30/P32 DUF1983 PF09327.11 OWF42766.1 - 1.4 9.1 2.6 57 3.9 0.1 4.8 3 3 3 7 7 7 0 Domain of unknown function (DUF1983) Cytadhesin_P30 PF07271.11 OWF42766.1 - 1.7 8.1 52.8 2.5 7.6 9.7 5.8 1 1 4 5 5 5 0 Cytadhesin P30/P32 Colipase-like PF15083.6 OWF42767.1 - 4.1e-05 23.6 21.5 0.0006 19.9 6.8 2.1 1 1 1 2 2 2 2 Colipase-like LRR_4 PF12799.7 OWF42767.1 - 2.1 8.9 8.0 3.9 8.0 1.3 3.0 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) OspD PF03207.13 OWF42768.1 - 0.052 12.9 1.3 0.099 12.0 0.1 1.8 1 1 0 1 1 1 0 Borrelia outer surface protein D (OspD) DUF1738 PF08401.11 OWF42768.1 - 0.33 11.1 2.4 0.65 10.1 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1738) Y_phosphatase PF00102.27 OWF42769.1 - 2.2e-79 266.3 0.1 8.1e-79 264.5 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase fn3 PF00041.21 OWF42769.1 - 7e-74 244.2 57.8 5.2e-09 36.3 0.1 14.0 14 0 0 14 14 14 12 Fibronectin type III domain DSPc PF00782.20 OWF42769.1 - 0.00097 19.0 0.1 0.0043 16.9 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Syndecan PF01034.20 OWF42769.1 - 0.0056 16.6 0.4 0.012 15.5 0.4 1.5 1 0 0 1 1 1 1 Syndecan domain 2-oxogl_dehyd_N PF16078.5 OWF42769.1 - 0.029 14.0 0.1 0.2 11.3 0.0 2.6 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus EphA2_TM PF14575.6 OWF42769.1 - 0.036 14.9 1.4 0.05 14.5 0.1 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 OWF42769.1 - 0.097 12.9 0.3 0.32 11.2 0.3 1.9 1 0 0 1 1 1 0 Glycophorin A Adeno_E3_CR2 PF02439.15 OWF42769.1 - 0.11 12.3 5.3 0.23 11.2 5.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Y_phosphatase3 PF13350.6 OWF42769.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family RNA_pol_Rpb5_N PF03871.14 OWF42769.1 - 0.16 12.5 0.9 36 5.0 0.1 3.9 4 0 0 4 4 4 0 RNA polymerase Rpb5, N-terminal domain Insulin_TMD PF17870.1 OWF42769.1 - 0.75 9.9 5.3 1.9 8.6 5.3 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EF-hand_7 PF13499.6 OWF42770.1 - 7.4e-06 26.3 3.1 0.033 14.6 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF42770.1 - 0.005 16.3 4.8 0.97 9.1 0.2 3.6 4 1 0 4 4 4 2 EF hand DUF5508 PF17621.2 OWF42770.1 - 0.0073 15.5 0.1 0.0095 15.1 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5508) CARD PF00619.21 OWF42770.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain Beta-lactamase2 PF13354.6 OWF42770.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family TPR_2 PF07719.17 OWF42771.1 - 2.3e-37 124.1 11.9 0.00015 21.6 0.3 11.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 OWF42771.1 - 3.6e-30 102.2 8.1 0.00078 19.7 0.1 10.5 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 OWF42771.1 - 7.5e-30 102.3 15.6 9.9e-06 25.1 0.0 9.7 8 3 2 10 10 10 7 TPR repeat TPR_1 PF00515.28 OWF42771.1 - 1.8e-29 100.3 19.4 0.00016 21.3 0.0 10.8 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF42771.1 - 2.9e-28 95.7 5.3 0.0014 18.7 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 OWF42771.1 - 9e-28 96.7 0.4 0.00011 22.8 0.2 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 OWF42771.1 - 1.8e-27 95.6 9.3 1.2e-05 25.8 0.0 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat DUF1736 PF08409.11 OWF42771.1 - 2.2e-27 94.8 1.4 7.4e-27 93.1 1.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_12 PF13424.6 OWF42771.1 - 1e-26 93.0 26.7 1.5e-06 28.4 0.6 7.8 2 2 5 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 OWF42771.1 - 2.8e-24 83.7 0.7 0.006 17.3 0.0 9.4 3 2 7 10 10 10 4 Tetratricopeptide repeat TPR_10 PF13374.6 OWF42771.1 - 8.7e-17 60.4 17.9 0.011 15.6 0.1 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 OWF42771.1 - 1.3e-15 56.2 4.9 0.004 17.1 0.0 8.8 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.6 OWF42771.1 - 3.3e-11 42.9 3.3 1.6e-07 30.9 0.3 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF42771.1 - 8.2e-10 38.8 13.0 0.00043 20.5 0.2 4.7 3 2 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OWF42771.1 - 1e-09 38.4 1.8 0.00098 19.2 0.0 6.3 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF42771.1 - 2.5e-08 34.0 0.8 0.036 14.7 0.0 6.3 7 0 0 7 7 5 1 Tetratricopeptide repeat BTAD PF03704.17 OWF42771.1 - 0.00037 21.0 6.0 0.68 10.4 0.1 4.6 2 2 1 4 4 4 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 OWF42771.1 - 0.00049 20.5 0.0 16 6.5 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.10 OWF42771.1 - 0.0013 17.9 0.2 0.022 13.8 0.2 2.1 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) EST1_DNA_bind PF10373.9 OWF42771.1 - 0.0087 15.6 2.6 0.63 9.5 0.6 2.7 3 0 0 3 3 2 1 Est1 DNA/RNA binding domain TPR_21 PF09976.9 OWF42771.1 - 0.011 15.5 10.4 0.71 9.6 0.0 4.7 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 OWF42771.1 - 0.014 14.8 4.4 0.17 11.3 0.4 3.2 2 1 1 4 4 4 0 Coatomer epsilon subunit DUF4192 PF13830.6 OWF42771.1 - 0.017 15.2 0.0 0.12 12.4 0.0 2.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4192) TPR_20 PF14561.6 OWF42771.1 - 0.051 13.9 7.0 7.2 7.0 0.9 5.3 2 2 3 5 5 5 0 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.6 OWF42771.1 - 0.11 12.4 0.1 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain NARP1 PF12569.8 OWF42771.1 - 0.22 10.4 11.9 0.22 10.4 0.1 3.8 3 1 2 5 5 5 0 NMDA receptor-regulated protein 1 ANAPC5 PF12862.7 OWF42771.1 - 0.29 11.2 3.5 32 4.7 0.2 4.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 SNAP PF14938.6 OWF42771.1 - 0.94 8.8 6.6 9.9 5.5 0.3 3.6 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 OWF42771.1 - 1.9 8.5 6.3 32 4.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OWF42771.1 - 8.4 6.4 6.1 54 3.8 0.5 4.0 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 Ank_2 PF12796.7 OWF42772.1 - 2.5e-15 56.8 0.0 3.4e-09 37.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF42772.1 - 1.2e-14 54.4 0.2 0.00016 22.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF42772.1 - 8.2e-12 45.1 1.0 2.4e-06 27.7 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF42772.1 - 2.3e-10 39.8 0.0 0.0072 16.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OWF42772.1 - 6e-10 39.1 0.0 2.1e-05 24.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Neurexophilin PF06312.12 OWF42774.1 - 2.2e-08 33.8 0.1 2.8e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF42774.1 - 0.0034 18.2 0.0 0.0074 17.1 0.0 1.5 2 0 0 2 2 2 1 Filamin/ABP280 repeat Sugar_tr PF00083.24 OWF42777.1 - 2.6e-36 125.5 21.0 4.1e-36 124.8 21.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF42777.1 - 1.3e-20 73.7 40.7 1.5e-10 40.6 20.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Ion_trans PF00520.31 OWF42778.1 - 6e-14 51.9 20.8 9.1e-14 51.3 20.8 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OWF42778.1 - 5.7e-11 41.8 13.9 5.7e-11 41.8 13.9 1.8 1 1 1 2 2 2 1 Polycystin cation channel Bac_export_2 PF01312.19 OWF42778.1 - 0.004 16.4 3.1 0.004 16.4 3.1 1.9 2 0 0 2 2 2 1 FlhB HrpN YscU SpaS Family DUF2157 PF09925.9 OWF42778.1 - 2.1 8.1 8.4 2.3 8.0 2.2 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Lectin_C PF00059.21 OWF42779.1 - 2.9e-14 53.7 0.9 2.9e-14 53.7 0.9 1.6 2 0 0 2 2 2 1 Lectin C-type domain SF-assemblin PF06705.11 OWF42779.1 - 0.0014 18.0 1.5 0.0022 17.4 1.5 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin Bac_thur_toxin PF01338.18 OWF42779.1 - 0.0043 16.5 1.8 0.0079 15.7 1.8 1.5 1 1 0 1 1 1 1 Bacillus thuringiensis toxin Baculo_PEP_C PF04513.12 OWF42779.1 - 0.0063 16.6 0.3 0.0099 15.9 0.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 OWF42779.1 - 0.01 16.3 0.4 0.026 15.0 0.4 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 OWF42779.1 - 0.014 13.4 0.3 0.019 12.9 0.3 1.0 1 0 0 1 1 1 0 Prominin Filament PF00038.21 OWF42779.1 - 0.017 14.7 1.3 0.025 14.2 1.3 1.1 1 0 0 1 1 1 0 Intermediate filament protein Scs3p PF10261.9 OWF42779.1 - 0.022 14.2 1.2 0.04 13.4 1.2 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM PDR_assoc PF08370.11 OWF42779.1 - 0.23 11.2 0.7 5.4 6.8 0.1 2.5 1 1 1 2 2 2 0 Plant PDR ABC transporter associated Pkinase PF00069.25 OWF42780.1 - 7.8e-44 150.0 0.0 2.1e-43 148.6 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42780.1 - 3.7e-41 141.1 0.0 8.2e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.23 OWF42780.1 - 4e-17 62.8 0.0 2.3e-16 60.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF42780.1 - 2.4e-07 30.8 0.0 8.2e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF42780.1 - 0.00061 19.7 1.6 0.0095 15.9 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase ABC1 PF03109.16 OWF42780.1 - 0.00066 19.8 4.2 0.0041 17.3 0.0 3.8 3 1 0 4 4 3 1 ABC1 family Kinase-like PF14531.6 OWF42780.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF42780.1 - 0.0023 16.9 0.0 0.0061 15.6 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain IIGP PF05049.13 OWF42780.1 - 0.0037 16.4 0.7 0.021 13.9 0.0 2.4 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 OWF42780.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 OWF42780.1 - 0.013 16.0 10.2 0.19 12.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 OWF42780.1 - 0.015 14.6 0.5 0.057 12.7 0.0 2.2 3 0 0 3 3 3 0 Septin Herpes_Helicase PF02689.14 OWF42780.1 - 0.02 12.8 0.2 1.7 6.5 0.3 2.1 2 0 0 2 2 2 0 Helicase AAA_29 PF13555.6 OWF42780.1 - 0.033 13.9 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF42780.1 - 0.038 14.5 2.5 0.045 14.3 0.0 2.3 2 1 0 2 2 2 0 ABC transporter T2SSE PF00437.20 OWF42780.1 - 0.039 13.0 0.1 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AIG1 PF04548.16 OWF42780.1 - 0.069 12.5 0.1 0.61 9.4 0.1 2.4 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 OWF42780.1 - 0.11 12.8 0.0 0.47 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OWF42780.1 - 0.17 11.2 0.5 1.3 8.4 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF445 PF04286.12 OWF42780.1 - 0.24 11.2 14.8 0.16 11.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF445) RIFIN PF02009.16 OWF42780.1 - 0.58 10.0 10.5 0.92 9.3 1.7 2.3 2 0 0 2 2 2 0 Rifin Rx_N PF18052.1 OWF42780.1 - 0.67 10.3 4.9 0.66 10.3 0.4 3.0 3 0 0 3 3 3 0 Rx N-terminal domain YlqD PF11068.8 OWF42780.1 - 7.3 7.0 11.7 2 8.8 2.0 3.0 2 1 0 3 3 3 0 YlqD protein Dynamin_N PF00350.23 OWF42781.1 - 2.7e-18 66.6 0.2 2.7e-18 66.6 0.2 2.6 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OWF42781.1 - 6.9e-08 32.6 0.3 3.7e-06 27.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Utp12 PF04003.12 OWF42781.1 - 0.023 15.0 0.4 0.11 12.8 0.4 2.2 1 0 0 1 1 1 0 Dip2/Utp12 Family AAA_16 PF13191.6 OWF42781.1 - 0.037 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OWF42781.1 - 0.042 12.9 0.0 0.13 11.3 0.0 1.9 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 OWF42781.1 - 0.27 10.3 6.4 0.55 9.2 0.1 2.7 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 OWF42781.1 - 0.38 10.7 2.7 0.49 10.3 0.1 2.4 3 0 0 3 3 3 0 RsgA GTPase DUF445 PF04286.12 OWF42781.1 - 1.3 8.7 14.7 0.18 11.6 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF445) Dynamin_N PF00350.23 OWF42782.1 - 1e-17 64.7 0.3 7.9e-17 61.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Pkinase PF00069.25 OWF42782.1 - 7.4e-14 51.7 0.0 2.9e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42782.1 - 3.4e-13 49.5 0.0 7.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.23 OWF42782.1 - 2.3e-07 30.9 0.1 9.4e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF42782.1 - 0.00062 19.7 0.1 0.0039 17.1 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 OWF42782.1 - 0.0053 15.9 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRPRB PF09439.10 OWF42782.1 - 0.0098 15.3 0.0 0.049 13.1 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit HMG_box_2 PF09011.10 OWF42782.1 - 0.033 14.8 1.6 2.7 8.7 0.1 2.7 2 0 0 2 2 2 0 HMG-box domain DUF2884 PF11101.8 OWF42782.1 - 0.14 11.6 0.1 0.14 11.6 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2884) DUF948 PF06103.11 OWF42782.1 - 0.47 10.7 3.9 0.86 9.9 0.3 3.2 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) SPT2 PF08243.11 OWF42782.1 - 0.63 10.6 2.9 2.8 8.5 0.4 2.9 3 0 0 3 3 3 0 SPT2 chromatin protein ABC_tran PF00005.27 OWF42782.1 - 1.2 9.6 5.2 0.41 11.2 0.1 2.7 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 OWF42783.1 - 7.5e-18 65.1 0.0 7.5e-18 65.1 0.0 2.7 3 1 0 3 3 3 1 Dynamin family Pkinase PF00069.25 OWF42783.1 - 5.6e-17 62.0 0.0 2.2e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42783.1 - 5.9e-12 45.4 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.23 OWF42783.1 - 1.3e-06 28.4 0.1 5e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF42783.1 - 0.034 14.1 3.3 0.04 13.8 0.3 2.8 2 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 OWF42783.1 - 0.36 11.4 2.5 0.53 10.8 0.0 2.6 3 0 0 3 3 3 0 ABC transporter L_HMGIC_fpl PF10242.9 OWF42784.1 - 3.1e-54 183.9 12.5 4e-54 183.6 12.5 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 OWF42784.1 - 1.1e-05 25.3 8.5 0.00028 20.8 10.8 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF42784.1 - 1.6e-05 24.7 11.0 0.0001 22.1 10.7 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF42784.1 - 0.0021 18.0 7.3 0.0021 18.0 7.3 2.0 2 0 0 2 2 2 1 Tight junction protein, Claudin-like Otopetrin PF03189.13 OWF42784.1 - 0.049 12.4 0.9 0.077 11.8 0.9 1.3 1 0 0 1 1 1 0 Otopetrin Atthog PF18800.1 OWF42784.1 - 0.24 11.3 9.5 0.036 14.0 5.4 1.8 1 1 0 1 1 1 0 Attenuator of Hedgehog DUF2207 PF09972.9 OWF42784.1 - 5.3 5.7 13.0 0.37 9.5 4.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 OWF42785.1 - 6.9e-39 133.8 6.9 1.1e-21 77.4 0.5 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42785.1 - 4.1e-11 42.7 0.4 1.1e-09 38.0 0.3 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase VlpA_repeat PF04649.12 OWF42785.1 - 9.9 6.7 8.0 6 7.3 3.2 3.3 2 0 0 2 2 2 0 Mycoplasma hyorhinis VlpA repeat PCAF_N PF06466.11 OWF42786.1 - 2.7e-123 410.4 3.3 5e-123 409.6 3.3 1.4 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 OWF42786.1 - 3.8e-23 81.3 1.6 1e-22 80.0 1.6 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OWF42786.1 - 2e-08 34.4 0.0 5.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF42786.1 - 2.6e-06 27.4 0.0 5.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF42786.1 - 1.2e-05 25.6 0.1 2.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RIBIOP_C PF04950.12 OWF42787.1 - 4.9e-121 403.7 0.1 4.9e-121 403.7 0.1 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OWF42787.1 - 1.1e-21 76.7 0.0 4e-21 74.9 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain IBB PF01749.20 OWF42787.1 - 0.00061 20.2 3.8 0.00061 20.2 3.8 2.9 2 1 0 2 2 2 1 Importin beta binding domain Hist_deacetyl PF00850.19 OWF42788.1 - 2.5e-51 175.0 0.0 3.3e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PaaX PF07848.12 OWF42789.1 - 0.0084 16.3 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 PaaX-like protein NAP PF00956.18 OWF42790.1 - 7.7e-25 87.6 18.3 2.9e-20 72.6 11.9 3.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 OWF42790.1 - 0.0025 17.8 0.4 0.0044 17.0 0.4 1.4 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Nore1-SARAH PF16517.5 OWF42790.1 - 0.16 11.9 4.4 1 9.3 0.3 2.5 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain MACPF PF01823.19 OWF42792.1 - 6.6e-21 75.4 0.1 1.6e-20 74.1 0.1 1.6 1 1 1 2 2 2 1 MAC/Perforin domain Cadherin_C_2 PF16492.5 OWF42792.1 - 0.0024 18.6 0.9 0.11 13.3 0.0 3.3 3 1 0 3 3 3 1 Cadherin cytoplasmic C-terminal DUF4690 PF15756.5 OWF42792.1 - 0.11 13.1 0.1 0.32 11.6 0.1 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage CoatB PF10389.9 OWF42792.1 - 0.61 10.0 4.5 1.6 8.7 4.2 1.9 2 0 0 2 2 2 0 Bacteriophage coat protein B MACPF PF01823.19 OWF42793.1 - 1.2e-21 77.8 0.2 3.1e-21 76.4 0.1 1.7 1 1 0 1 1 1 1 MAC/Perforin domain Ank_2 PF12796.7 OWF42794.1 - 0.00062 20.3 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF42794.1 - 0.00072 19.8 0.1 0.05 14.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Josephin PF02099.17 OWF42794.1 - 0.0024 18.0 0.0 0.0068 16.5 0.0 1.7 1 0 0 1 1 1 1 Josephin Hid1 PF12722.7 OWF42794.1 - 1.4 7.0 5.2 2.2 6.3 5.2 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-C2H2 PF00096.26 OWF42795.1 - 7.2e-21 73.4 50.6 4e-05 23.8 3.1 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF42795.1 - 9.1e-21 73.3 44.2 4.1e-09 36.4 0.7 7.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF42795.1 - 1.3e-16 59.9 49.0 0.0071 17.1 0.6 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF42795.1 - 1.6e-08 34.6 24.1 0.054 13.8 0.3 6.0 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding SET PF00856.28 OWF42795.1 - 9.8e-06 26.0 0.1 2.8e-05 24.6 0.0 1.6 1 1 1 2 2 2 1 SET domain zf-C2H2_11 PF16622.5 OWF42795.1 - 4.9e-05 23.0 33.8 0.063 13.1 0.4 5.7 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-Di19 PF05605.12 OWF42795.1 - 0.0032 17.7 26.3 1.2 9.4 7.5 3.4 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OWF42795.1 - 0.01 16.2 31.7 2.8 8.4 0.2 6.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF42795.1 - 0.022 14.7 35.4 0.053 13.5 2.6 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OWF42795.1 - 0.037 14.0 23.0 0.11 12.4 2.5 5.6 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 OWF42795.1 - 0.066 13.5 31.3 0.85 10.0 3.5 5.6 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) DUF2111 PF09884.9 OWF42795.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) zinc_ribbon_15 PF17032.5 OWF42795.1 - 0.31 11.8 22.0 2.4 8.9 2.2 3.7 1 1 3 4 4 4 0 zinc-ribbon family PyrI_C PF02748.15 OWF42795.1 - 4.6 7.2 22.0 0.46 10.4 0.2 5.2 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 OWF42795.1 - 5 7.3 23.8 4.1 7.6 1.8 4.6 3 2 1 4 4 4 0 Zinc ribbon domain Type2_restr_D3 PF16902.5 OWF42796.1 - 9.1e-06 25.5 110.6 43 4.1 0.1 27.5 28 2 0 28 28 28 11 Type-2 restriction enzyme D3 domain DUF4573 PF15140.6 OWF42796.1 - 3.1e-05 23.8 13.1 0.29 10.9 0.6 5.1 1 1 5 6 6 6 5 Domain of unknown function (DUF4573) DUF4915 PF16261.5 OWF42796.1 - 0.83 8.8 24.1 3.3 6.8 0.2 6.9 1 1 6 8 8 8 0 Domain of unknown function (DUF4915) DnaJ_CXXCXGXG PF00684.19 OWF42797.1 - 0.00028 21.2 1.8 0.00074 19.8 1.8 1.8 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.10 OWF42797.1 - 0.027 14.2 3.7 0.061 13.0 3.7 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain Anti-TRAP PF15777.5 OWF42797.1 - 0.32 11.0 2.3 0.78 9.7 2.3 1.7 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ank_2 PF12796.7 OWF42798.1 - 4.4e-50 168.2 2.8 1.9e-16 60.4 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF42798.1 - 1e-34 118.5 0.0 1.8e-12 47.5 0.0 6.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF42798.1 - 3.7e-33 109.8 0.1 8.8e-05 22.6 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 OWF42798.1 - 9.6e-24 82.7 0.2 3.5e-07 30.4 0.0 6.9 5 2 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF42798.1 - 1.8e-18 66.4 0.1 8.4e-06 26.0 0.0 6.2 2 1 5 7 7 7 5 Ankyrin repeats (many copies) CdAMP_rec PF06153.11 OWF42798.1 - 0.046 13.9 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Cyclic-di-AMP receptor TYW3 PF02676.14 OWF42798.1 - 0.068 12.5 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 Orn_Arg_deC_N PF02784.16 OWF42798.1 - 0.083 12.2 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Nanovirus_coat PF04660.12 OWF42798.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Nanovirus coat protein Iso_dh PF00180.20 OWF42799.1 - 4.1e-67 226.8 0.0 4.8e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ApeC PF16977.5 OWF42800.1 - 1.2e-45 156.0 0.0 1.2e-45 156.0 0.0 2.4 2 0 0 2 2 2 1 C-terminal domain of apextrin Ldl_recept_a PF00057.18 OWF42800.1 - 7.1e-40 134.9 86.3 5.1e-08 33.0 14.8 7.4 6 0 0 6 6 6 6 Low-density lipoprotein receptor domain class A 7tm_1 PF00001.21 OWF42800.1 - 8.8e-24 84.2 10.3 1.3e-23 83.6 10.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CUB PF00431.20 OWF42800.1 - 2.9e-13 50.1 0.0 3.9e-05 23.9 0.0 3.0 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.25 OWF42800.1 - 2.6e-12 47.0 0.0 2.1e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain Lectin_C PF00059.21 OWF42800.1 - 3.7e-08 34.1 0.1 3.7e-08 34.1 0.1 2.4 2 0 0 2 2 2 1 Lectin C-type domain Serpentine_r_xa PF03383.15 OWF42800.1 - 0.01 15.8 3.2 0.024 14.6 3.2 1.6 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa DUF3895 PF13034.6 OWF42801.1 - 0.077 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) DUF19 PF01579.18 OWF42802.1 - 0.025 14.4 0.6 0.034 14.0 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF19) PGDYG PF14083.6 OWF42803.1 - 3e-23 82.0 8.7 0.083 13.1 0.2 11.0 1 1 10 11 11 11 10 PGDYG protein GHL6 PF14871.6 OWF42803.1 - 0.00025 21.2 3.4 40 4.3 0.0 7.2 1 1 8 10 10 10 1 Hypothetical glycosyl hydrolase 6 Castor1_N PF18700.1 OWF42803.1 - 0.0098 15.7 82.8 11 6.0 0.2 21.2 1 1 17 21 21 21 8 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Carb_anhydrase PF00194.21 OWF42804.1 - 1.5e-67 227.8 0.0 1.8e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3829 PF12889.7 OWF42804.1 - 0.14 11.6 0.3 0.2 11.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) EGF_CA PF07645.15 OWF42805.1 - 6e-08 32.8 41.4 5.6e-07 29.7 12.0 6.8 5 2 1 6 6 6 2 Calcium-binding EGF domain DUF3456 PF11938.8 OWF42805.1 - 1.1e-07 32.6 10.4 8.7e-06 26.3 0.0 3.1 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP Laminin_EGF PF00053.24 OWF42805.1 - 0.0003 20.8 14.0 0.0003 20.8 14.0 6.6 2 1 4 6 6 6 1 Laminin EGF domain cEGF PF12662.7 OWF42805.1 - 0.00099 19.0 3.0 0.00099 19.0 3.0 7.4 6 1 1 7 7 7 4 Complement Clr-like EGF-like SLATT_1 PF18181.1 OWF42805.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 HILPDA PF15220.6 OWF42805.1 - 2 8.6 3.7 4.2 7.6 0.1 2.8 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated Pkinase PF00069.25 OWF42806.1 - 2.3e-46 158.3 0.0 4.8e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42806.1 - 1.8e-30 106.1 0.1 3.7e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_CCD1 PF18394.1 OWF42806.1 - 2.7e-22 79.6 16.7 5.5e-22 78.6 16.7 1.5 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 TBK1_ULD PF18396.1 OWF42806.1 - 1.1e-14 54.1 0.3 3e-14 52.7 0.3 1.8 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Kinase-like PF14531.6 OWF42806.1 - 7.7e-08 32.0 0.0 0.00015 21.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OWF42806.1 - 1.6e-05 23.9 1.6 2.2e-05 23.4 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OWF42806.1 - 0.00017 21.0 0.0 0.0005 19.5 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_Mga PF08280.11 OWF42806.1 - 0.027 14.5 0.1 0.11 12.5 0.1 2.1 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Rad60-SLD PF11976.8 OWF42806.1 - 0.036 13.9 0.0 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sulfotransfer_2 PF03567.14 OWF42807.1 - 3.7e-40 138.4 0.2 5e-40 138.0 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF42807.1 - 0.05 13.1 0.0 0.32 10.4 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase domain L1R_F9L PF02442.17 OWF42807.1 - 0.17 11.7 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses DUF1939 PF09154.10 OWF42808.1 - 0.003 17.7 5.6 14 5.9 0.1 5.0 2 2 4 6 6 6 3 Domain of unknown function (DUF1939) ING PF12998.7 OWF42808.1 - 8.6 7.0 24.4 23 5.7 6.5 4.8 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding FYTT PF07078.11 OWF42811.1 - 0.00054 19.4 44.0 0.14 11.4 44.0 3.3 1 1 0 1 1 1 1 Forty-two-three protein PspA_IM30 PF04012.12 OWF42811.1 - 0.45 10.1 8.1 0.075 12.6 3.8 1.8 2 0 0 2 2 2 0 PspA/IM30 family DUF4407 PF14362.6 OWF42811.1 - 9.7 5.4 10.1 15 4.8 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_C PF00059.21 OWF42812.1 - 1.1e-17 64.7 2.2 1.9e-17 63.9 2.2 1.4 1 0 0 1 1 1 1 Lectin C-type domain Baculo_PEP_C PF04513.12 OWF42812.1 - 0.019 15.0 0.9 0.029 14.4 0.9 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 OWF42812.1 - 0.058 12.0 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A LPP PF04728.13 OWF42812.1 - 0.091 13.2 1.0 0.21 12.0 0.2 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper NUDE_C PF04880.13 OWF42813.1 - 0.7 10.3 5.7 1.1 9.7 5.7 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Fumble PF03630.14 OWF42814.1 - 5.4e-136 453.1 0.1 7e-136 452.7 0.1 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 OWF42814.1 - 1.4e-41 142.6 0.1 2.2e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 YqgB PF11036.8 OWF42814.1 - 0.0046 16.7 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Virulence promoting factor DASH_Dad3 PF08656.10 OWF42816.1 - 0.00058 19.9 2.0 0.00058 19.9 2.0 3.9 2 1 2 4 4 4 1 DASH complex subunit Dad3 Filament PF00038.21 OWF42816.1 - 0.0011 18.7 31.8 0.25 10.9 7.8 3.0 1 1 0 2 2 2 2 Intermediate filament protein Syntaxin-6_N PF09177.11 OWF42816.1 - 0.0093 16.5 4.1 0.0093 16.5 4.1 4.4 1 1 2 3 3 3 1 Syntaxin 6, N-terminal HAUS-augmin3 PF14932.6 OWF42816.1 - 0.011 15.4 6.5 0.011 15.4 6.5 3.2 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Prefoldin PF02996.17 OWF42816.1 - 0.013 15.4 0.2 0.013 15.4 0.2 4.8 3 2 3 6 6 6 0 Prefoldin subunit NPV_P10 PF05531.12 OWF42816.1 - 0.015 15.8 0.7 0.015 15.8 0.7 4.3 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 OWF42816.1 - 0.019 13.1 26.1 0.03 12.5 10.7 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 OWF42816.1 - 0.087 12.9 30.8 0.099 12.7 4.2 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OWF42816.1 - 0.21 11.8 32.5 0.026 14.7 4.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family YcbB PF08664.10 OWF42816.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.6 3 1 1 4 4 4 0 YcbB domain Spc7 PF08317.11 OWF42816.1 - 0.28 10.0 34.2 0.58 9.0 8.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 OWF42816.1 - 0.33 8.4 34.9 1.9 5.9 33.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Dna2 PF08696.11 OWF42816.1 - 0.37 10.6 16.5 0.056 13.3 8.7 3.0 1 1 1 2 2 2 0 DNA replication factor Dna2 Baculo_PEP_C PF04513.12 OWF42816.1 - 0.43 10.6 24.9 5.7 7.0 4.9 3.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 OWF42816.1 - 0.56 10.3 14.2 0.93 9.6 0.2 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) CLZ PF16526.5 OWF42816.1 - 0.75 10.2 29.4 0.43 11.0 2.9 5.6 2 1 5 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HisKA_3 PF07730.13 OWF42816.1 - 1.2 9.7 11.3 19 5.9 0.2 5.1 3 2 1 5 5 5 0 Histidine kinase TPR_MLP1_2 PF07926.12 OWF42816.1 - 1.3 9.0 33.4 0.8 9.8 6.1 4.7 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein BshC PF10079.9 OWF42816.1 - 1.9 7.2 28.2 4.5 5.9 3.4 2.9 2 1 0 2 2 2 0 Bacillithiol biosynthesis BshC Exonuc_VII_L PF02601.15 OWF42816.1 - 2.8 7.4 27.4 6.1 6.3 10.0 2.5 1 1 1 2 2 2 0 Exonuclease VII, large subunit FAM76 PF16046.5 OWF42816.1 - 3.3 7.0 31.8 1 8.7 6.8 3.0 1 1 0 2 2 2 0 FAM76 protein KxDL PF10241.9 OWF42816.1 - 3.9 7.8 28.5 1.8 8.9 1.0 4.3 2 1 2 4 4 4 0 Uncharacterized conserved protein RmuC PF02646.16 OWF42816.1 - 4.9 6.2 31.6 0.78 8.8 3.1 4.8 1 1 4 5 5 5 0 RmuC family HMMR_N PF15905.5 OWF42816.1 - 5 6.5 37.9 0.52 9.7 11.4 3.1 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Sulfatase_C PF14707.6 OWF42816.1 - 8.8 7.1 11.5 16 6.3 1.6 3.3 2 1 2 4 4 4 0 C-terminal region of aryl-sulfatase DUF4407 PF14362.6 OWF42816.1 - 9.5 5.5 28.7 6.2 6.1 12.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.10 OWF42816.1 - 9.9 6.5 14.2 6.2 7.2 0.4 3.9 3 1 1 4 4 4 0 Osmosensory transporter coiled coil Neur_chan_LBD PF02931.23 OWF42817.1 - 5.9e-43 146.8 0.2 8.3e-43 146.3 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF42817.1 - 1e-17 65.0 8.2 9.4e-11 42.2 4.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DHFR_1 PF00186.19 OWF42817.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Dihydrofolate reductase SMC_N PF02463.19 OWF42818.1 - 5e-71 238.6 33.2 4.9e-38 130.8 3.9 2.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OWF42818.1 - 2.4e-24 85.9 0.0 7.9e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OWF42818.1 - 7.3e-13 49.0 4.8 1.5e-05 25.0 0.1 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF42818.1 - 3.9e-10 40.6 1.0 3.9e-10 40.6 1.0 7.0 2 2 2 4 4 2 1 AAA domain AAA_29 PF13555.6 OWF42818.1 - 7.9e-05 22.3 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 OWF42818.1 - 0.0016 18.7 17.1 0.0016 18.7 17.1 6.7 2 2 2 5 5 5 1 Autophagy protein 16 (ATG16) FliJ PF02050.16 OWF42818.1 - 0.0022 18.2 7.1 0.0022 18.2 7.1 7.8 3 2 5 8 8 8 4 Flagellar FliJ protein AAA_15 PF13175.6 OWF42818.1 - 0.0025 17.6 39.2 0.0025 17.6 39.2 4.9 2 2 0 2 2 1 1 AAA ATPase domain ERM PF00769.19 OWF42818.1 - 0.0033 17.3 25.3 0.0033 17.3 25.3 6.0 2 2 3 5 5 5 2 Ezrin/radixin/moesin family DUF745 PF05335.13 OWF42818.1 - 0.0069 16.1 13.7 0.0069 16.1 13.7 6.0 2 2 2 5 5 5 3 Protein of unknown function (DUF745) Arm-DNA-bind_2 PF12167.8 OWF42818.1 - 0.017 15.1 0.7 0.017 15.1 0.7 4.9 6 0 0 6 6 6 0 Arm DNA-binding domain SbcCD_C PF13558.6 OWF42818.1 - 0.038 14.2 0.0 0.9 9.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 OWF42818.1 - 0.15 12.6 0.0 0.15 12.6 0.0 6.2 3 2 0 3 3 2 0 ABC transporter Spc7 PF08317.11 OWF42818.1 - 0.25 10.2 124.7 0.007 15.3 20.2 6.9 2 2 5 7 7 7 0 Spc7 kinetochore protein MscS_porin PF12795.7 OWF42818.1 - 1.9 8.0 71.9 4 6.9 24.9 5.5 2 2 3 5 5 5 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 OWF42818.1 - 3.6 7.6 78.7 1.2 9.2 4.8 7.8 2 2 5 7 7 7 0 Laminin Domain II Sulfatase PF00884.23 OWF42820.1 - 6.1e-11 42.3 0.0 6.5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4410 PF14366.6 OWF42820.1 - 0.035 14.0 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Dicty_CAR PF05462.11 OWF42821.1 - 1.3e-17 64.0 10.8 1.6e-17 63.6 10.8 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 OWF42821.1 - 8e-11 41.9 0.0 8e-11 41.9 0.0 2.1 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF5557 PF17712.1 OWF42821.1 - 0.017 15.1 3.1 3.2 7.8 0.4 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5557) Sulfotransfer_2 PF03567.14 OWF42822.1 - 4.2e-35 121.9 5.8 6.8e-34 117.9 2.9 2.1 2 0 0 2 2 2 2 Sulfotransferase family EPTP PF03736.17 OWF42823.1 - 0.0072 16.3 0.0 70 3.5 0.0 4.7 5 0 0 5 5 5 0 EPTP domain YlbE PF14003.6 OWF42823.1 - 0.26 11.8 5.2 42 4.7 0.1 3.9 3 1 1 4 4 4 0 YlbE-like protein zf-CCHC_2 PF13696.6 OWF42823.1 - 0.59 10.0 18.6 78 3.2 0.1 6.6 6 0 0 6 6 6 0 Zinc knuckle EPF PF17181.4 OWF42823.1 - 0.66 10.0 16.7 8 6.6 0.0 5.6 2 1 2 4 4 4 0 Epidermal patterning factor proteins Carb_bind PF10645.9 OWF42823.1 - 5.6 7.3 18.1 15 5.9 0.2 5.7 6 0 0 6 6 6 0 Carbohydrate binding SNF PF00209.18 OWF42824.1 - 2.1e-172 574.5 42.6 3.1e-172 573.9 42.6 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Neur_chan_LBD PF02931.23 OWF42825.1 - 5.6e-41 140.4 0.0 9.1e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF42825.1 - 9.6e-11 42.2 10.1 9.6e-11 42.2 10.1 1.8 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF42826.1 - 5.8e-42 143.6 0.6 7.8e-42 143.2 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF42826.1 - 1.5e-09 38.3 6.2 2.4e-09 37.6 6.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GWT1 PF06423.12 OWF42826.1 - 0.0094 16.1 2.9 0.033 14.3 2.9 2.0 1 1 0 1 1 1 1 GWT1 DUF5313 PF17240.2 OWF42826.1 - 2.4 8.6 7.1 4.4 7.7 0.9 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Neur_chan_memb PF02932.16 OWF42827.1 - 6.1e-14 52.6 1.7 7.2e-14 52.4 1.7 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2678 PF10856.8 OWF42827.1 - 0.04 13.8 1.7 0.057 13.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) HECT PF00632.25 OWF42829.1 - 7.2e-07 29.0 0.1 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Neur_chan_LBD PF02931.23 OWF42830.1 - 3.2e-45 154.2 1.0 4.2e-45 153.8 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF42830.1 - 3e-07 30.8 4.4 4.4e-07 30.2 4.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GWT1 PF06423.12 OWF42830.1 - 0.018 15.2 3.9 0.051 13.7 3.7 1.7 1 1 0 1 1 1 0 GWT1 Tetraspanin PF00335.20 OWF42831.1 - 6.7e-25 88.1 12.0 8e-25 87.9 12.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3671 PF12420.8 OWF42831.1 - 0.13 12.4 1.8 1.6 8.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function zf-MYND PF01753.18 OWF42832.1 - 4.5e-10 39.5 16.0 7.4e-10 38.8 16.0 1.3 1 0 0 1 1 1 1 MYND finger BNR_2 PF13088.6 OWF42832.1 - 0.078 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain PolC_DP2 PF03833.13 OWF42832.1 - 0.48 8.2 6.4 0.57 8.0 6.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 OWF42832.1 - 4.7 7.6 12.0 11 6.5 12.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OWF42833.1 - 1.7e-40 136.8 89.8 9.4e-11 41.6 16.3 4.4 4 0 0 4 4 4 4 MYND finger PUD1_2 PF18457.1 OWF42833.1 - 0.024 14.6 0.2 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Up-Regulated in long-lived daf-2 Ecl1 PF12855.7 OWF42833.1 - 0.21 12.7 42.1 2.3 9.4 2.5 4.5 4 0 0 4 4 4 0 ECL1/2/3 zinc binding proteins G-patch PF01585.23 OWF42834.1 - 1e-17 63.7 6.4 2e-17 62.8 6.4 1.5 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 OWF42834.1 - 9.2e-16 57.6 14.9 9.2e-16 57.6 14.9 2.3 2 0 0 2 2 2 1 OCRE domain G-patch_2 PF12656.7 OWF42834.1 - 2.7e-09 37.0 0.8 2.7e-09 37.0 0.8 2.7 2 0 0 2 2 2 1 G-patch domain zf-RanBP PF00641.18 OWF42834.1 - 6.2e-06 25.4 4.3 1.7e-05 24.0 4.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 OWF42834.1 - 6.3e-05 22.7 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.13 OWF42834.1 - 0.0076 15.9 1.5 0.0076 15.9 1.5 3.0 3 0 0 3 3 3 1 RED-like protein N-terminal region MAP1B_neuraxin PF00414.17 OWF42834.1 - 3.6 7.3 14.5 0.049 13.2 2.7 2.8 1 1 1 2 2 2 0 Neuraxin and MAP1B repeat Sulfotransfer_1 PF00685.27 OWF42835.1 - 1.2e-15 57.8 0.4 3.8e-15 56.1 0.4 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF42835.1 - 2.4e-14 54.3 0.0 4.5e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF42836.1 - 7.9e-09 35.4 0.1 1.3e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF42836.1 - 2.5e-08 34.6 0.0 3.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Nbl1_Borealin_N PF10444.9 OWF42836.1 - 0.22 11.2 1.4 0.27 10.9 0.2 1.8 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DHR-2 PF06920.13 OWF42837.1 - 1.8e-75 254.6 7.1 1.4e-74 251.7 7.1 2.3 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 OWF42837.1 - 2.2e-70 237.5 0.1 4.5e-70 236.5 0.1 1.6 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 OWF42837.1 - 1.7e-43 148.7 0.1 4.6e-43 147.3 0.1 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.17 OWF42837.1 - 5e-06 26.1 0.1 1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PI3K_C2 PF00792.24 OWF42837.1 - 0.00022 21.1 0.0 0.00061 19.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 SH3_1 PF00018.28 OWF42837.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain C2 PF00168.30 OWF42837.1 - 0.0025 18.1 0.0 0.0072 16.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.6 OWF42837.1 - 0.0025 17.6 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 OWF42838.1 - 1.1e-13 51.4 2.5 2e-06 27.9 0.8 2.6 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) DUF3350 PF11830.8 OWF42838.1 - 2.4e-13 50.2 7.0 2.4e-13 50.2 7.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3350) Peptidase_C12 PF01088.21 OWF42839.1 - 2.4e-57 194.1 0.0 2.8e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RrnaAD PF00398.20 OWF42840.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_21 PF05050.12 OWF42840.1 - 0.0069 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Chal_sti_synt_C PF02797.15 OWF42840.1 - 0.039 13.9 0.1 0.09 12.8 0.0 1.6 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain RrnaAD PF00398.20 OWF42841.1 - 0.0013 17.9 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF2325 PF10087.9 OWF42841.1 - 0.019 15.1 0.1 0.038 14.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Chal_sti_synt_C PF02797.15 OWF42841.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Methyltransf_7 PF03492.15 OWF42842.1 - 3.5e-29 102.1 0.0 4.7e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Ank_2 PF12796.7 OWF42844.1 - 8.7e-76 250.6 16.2 1.7e-12 47.8 0.0 8.6 2 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF42844.1 - 2e-49 165.0 9.0 3.2e-06 27.3 0.0 11.3 2 1 9 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 OWF42844.1 - 6.9e-44 146.5 11.0 0.012 16.1 0.0 11.7 12 0 0 12 12 11 10 Ankyrin repeat Ank_3 PF13606.6 OWF42844.1 - 1.2e-43 142.1 9.0 0.0091 16.4 0.0 13.6 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.6 OWF42844.1 - 1.3e-39 134.1 12.4 5.8e-05 23.6 0.1 12.1 9 3 3 12 12 12 10 Ankyrin repeats (many copies) HEPN_DZIP3 PF18738.1 OWF42844.1 - 2.4e-28 98.7 0.0 4.5e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN Prok_Ub PF14454.6 OWF42844.1 - 2.6e-08 33.4 3.0 1.2e+02 2.5 0.0 9.8 10 0 0 10 10 10 0 Prokaryotic Ubiquitin DUF1664 PF07889.12 OWF42844.1 - 0.00023 21.2 0.8 0.62 10.1 0.1 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) LPP PF04728.13 OWF42844.1 - 0.00051 20.4 5.8 1.7 9.1 0.1 4.0 3 1 2 5 5 4 3 Lipoprotein leucine-zipper NPV_P10 PF05531.12 OWF42844.1 - 0.00067 20.1 9.7 1.6 9.2 3.7 4.1 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 OWF42844.1 - 0.018 15.1 0.2 3.7 7.6 0.0 3.2 2 1 0 2 2 2 0 Laminin Domain II COG7 PF10191.9 OWF42844.1 - 0.054 11.7 0.5 2.3 6.3 0.1 2.2 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) COG2 PF06148.11 OWF42844.1 - 0.059 13.5 0.3 17 5.5 0.1 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FAD_binding_5 PF00941.21 OWF42844.1 - 0.083 12.6 0.0 38 3.9 0.0 3.5 3 1 0 3 3 3 0 FAD binding domain in molybdopterin dehydrogenase Halo_GVPC PF05465.13 OWF42844.1 - 1.6 9.1 7.3 32 4.9 0.4 3.8 1 1 4 5 5 5 0 Halobacterial gas vesicle protein C (GVPC) repeat Lectin_C PF00059.21 OWF42845.1 - 1.5e-16 61.0 3.3 1.9e-16 60.7 3.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain FYVE PF01363.21 OWF42846.1 - 0.05 13.7 10.4 0.092 12.9 10.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.7 OWF42846.1 - 0.082 12.9 9.5 2.5 8.2 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 OWF42846.1 - 0.16 11.9 12.1 2.4 8.1 11.6 2.3 1 1 1 2 2 2 0 PHD-finger zf-AN1 PF01428.16 OWF42846.1 - 0.36 11.0 11.7 3.4 7.9 7.4 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger DUF4637 PF15470.6 OWF42846.1 - 0.46 10.2 10.7 0.92 9.2 4.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) tRNA_bind_3 PF17176.4 OWF42847.1 - 0.093 13.0 1.0 0.16 12.3 1.0 1.3 1 0 0 1 1 1 0 tRNA-binding domain Effector_1 PF04518.12 OWF42847.1 - 0.24 10.5 1.0 0.34 10.0 1.0 1.2 1 0 0 1 1 1 0 Effector from type III secretion system 7tm_1 PF00001.21 OWF42848.1 - 1.1e-36 126.6 14.1 1.1e-36 126.6 14.1 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SGL PF08450.12 OWF42850.1 - 0.013 15.1 0.1 0.26 10.8 0.1 2.8 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF42850.1 - 0.015 15.4 0.6 1.3 9.2 0.0 3.9 4 0 0 4 4 4 0 NHL repeat JAB PF01398.21 OWF42851.1 - 1.8e-37 127.9 0.1 4.1e-37 126.8 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 OWF42851.1 - 4.7e-29 100.4 3.6 1.1e-28 99.2 3.6 1.6 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 OWF42851.1 - 8.4e-10 38.5 0.1 1.3e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 OWF42851.1 - 4.8e-05 23.5 0.1 0.00015 21.9 0.0 1.8 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0172) SIKE PF05769.11 OWF42851.1 - 0.028 14.3 0.9 0.028 14.3 0.9 1.6 2 0 0 2 2 2 0 SIKE family SIMPL PF04402.14 OWF42851.1 - 0.045 14.2 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Cep57_CLD_2 PF14197.6 OWF42851.1 - 0.71 10.0 6.5 0.31 11.2 1.4 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Fibrinogen_C PF00147.18 OWF42852.1 - 1.7e-22 80.3 1.1 2.3e-22 79.9 1.1 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.13 OWF42852.1 - 0.031 14.7 2.1 0.094 13.1 2.1 1.9 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 OWF42852.1 - 0.19 11.9 5.2 0.54 10.4 4.2 2.2 2 1 0 2 2 2 0 Laminin EGF domain ADAM_CR_2 PF17771.1 OWF42853.1 - 1e-15 58.0 9.0 1e-15 58.0 9.0 3.0 2 1 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF42853.1 - 4.9e-13 49.7 0.0 1.1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin PF01421.19 OWF42853.1 - 1.8e-11 44.3 1.4 5.7e-11 42.7 0.0 2.5 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 OWF42853.1 - 1.1e-09 38.4 0.3 2.8e-09 37.1 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF42853.1 - 3.6e-07 30.0 0.1 7.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF42853.1 - 0.00011 22.7 0.5 0.00033 21.1 0.5 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF42853.1 - 0.024 14.5 0.3 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 Matrixin 7tm_1 PF00001.21 OWF42854.1 - 9e-53 179.3 17.9 1.2e-52 178.8 17.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF42854.1 - 2.6e-07 30.3 15.5 5.4e-07 29.2 15.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF42854.1 - 0.0007 19.4 9.9 0.0016 18.3 9.9 1.6 1 1 0 1 1 1 1 Olfactory receptor ThiF PF00899.21 OWF42855.1 - 4.7e-51 173.5 0.1 8.8e-51 172.6 0.1 1.4 1 1 1 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.14 OWF42855.1 - 0.0047 16.5 0.6 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 OWF42855.1 - 0.025 14.0 0.3 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OWF42855.1 - 0.085 12.1 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 OWF42855.1 - 0.13 12.5 0.8 1.2 9.4 0.8 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OWF42855.1 - 0.14 12.5 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain SNF PF00209.18 OWF42856.1 - 3.4e-12 45.8 3.8 4.2e-12 45.5 3.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Trypsin_2 PF13365.6 OWF42857.1 - 2.5e-08 35.0 0.0 4.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF42857.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Trypsin ABA_GPCR PF12430.8 OWF42858.1 - 3.6e-42 144.2 12.3 3.6e-42 144.2 12.3 2.4 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OWF42858.1 - 2.3e-26 91.7 0.1 6.4e-26 90.2 0.1 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF1772 PF08592.11 OWF42858.1 - 0.22 11.8 12.7 0.88 9.9 0.0 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF1772) Gemini_mov PF01708.16 OWF42858.1 - 0.25 11.1 1.0 1.4 8.7 1.0 2.3 1 0 0 1 1 1 0 Geminivirus putative movement protein UCH PF00443.29 OWF42859.1 - 3.2e-53 180.8 0.3 6.4e-53 179.9 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF42859.1 - 2.1e-09 37.4 0.5 8.2e-08 32.2 0.5 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OWF42859.1 - 0.016 14.7 0.3 3.5 7.0 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TPR_2 PF07719.17 OWF42859.1 - 0.023 14.8 0.4 0.086 13.0 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat CLZ PF16526.5 OWF42859.1 - 0.058 13.8 2.0 12 6.3 0.1 3.4 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 OWF42859.1 - 0.12 12.0 0.6 4 7.0 0.0 2.8 2 0 0 2 2 2 0 fzo-like conserved region UIM PF02809.20 OWF42859.1 - 0.14 12.1 9.1 0.33 11.0 1.7 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif Orthopox_A5L PF06193.11 OWF42859.1 - 1.5 8.2 8.8 0.82 9.1 0.4 2.8 3 0 0 3 3 3 0 Orthopoxvirus A5L protein-like Keratin_B2_2 PF13885.6 OWF42861.1 - 1.9e-09 37.3 65.3 5.4e-05 23.1 27.9 3.6 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 OWF42861.1 - 4.3e-06 26.8 62.0 0.00044 20.3 21.5 2.3 1 1 1 2 2 2 2 Keratin, high sulfur B2 protein FAP PF07174.11 OWF42861.1 - 5.2 6.4 15.0 2.2 7.6 10.3 1.9 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) Keratin_B2_2 PF13885.6 OWF42862.1 - 5.4e-10 39.1 102.1 0.24 11.4 9.6 5.3 1 1 1 3 3 3 2 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 OWF42862.1 - 2.3e-07 30.9 74.9 0.02 14.9 20.4 3.2 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein SK_channel PF03530.14 OWF42864.1 - 3.9e-39 133.2 3.1 3.9e-39 133.2 3.1 2.1 3 0 0 3 3 3 1 Calcium-activated SK potassium channel CaMBD PF02888.16 OWF42864.1 - 8.4e-20 70.8 1.1 1.8e-19 69.7 1.1 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 OWF42864.1 - 1.5e-14 53.7 0.7 1.5e-14 53.7 0.7 2.3 2 1 1 3 3 3 1 Ion channel SNF PF00209.18 OWF42865.1 - 1.7e-96 324.0 36.7 4.2e-54 184.1 24.1 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family DUF4199 PF13858.6 OWF42866.1 - 0.0004 20.8 0.3 0.0004 20.8 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) Clc-like PF07062.12 OWF42866.1 - 0.011 15.2 1.4 0.011 15.2 1.4 2.4 1 1 0 2 2 2 0 Clc-like SUR7 PF06687.12 OWF42866.1 - 0.048 13.3 20.2 0.025 14.2 3.1 2.3 1 1 1 2 2 2 0 SUR7/PalI family YfhO PF09586.10 OWF42866.1 - 0.17 10.1 6.4 0.14 10.4 5.2 1.4 1 1 0 1 1 1 0 Bacterial membrane protein YfhO DUF2070 PF09843.9 OWF42866.1 - 0.44 8.8 12.7 0.57 8.4 12.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_5 PF13346.6 OWF42866.1 - 7.8 6.0 21.7 3.5 7.1 17.3 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DENN PF02141.21 OWF42868.1 - 2.1e-32 112.6 0.7 4.3e-32 111.6 0.7 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OWF42868.1 - 6.4e-19 68.5 0.3 2.4e-18 66.7 0.3 2.1 1 0 0 1 1 1 1 uDENN domain hnRNP_Q_AcD PF18360.1 OWF42869.1 - 3.5e-44 148.6 0.0 0.66 10.0 0.0 22.0 1 1 45 46 46 46 46 Heterogeneous nuclear ribonucleoprotein Q acidic domain MFS_1 PF07690.16 OWF42870.1 - 4.3e-40 137.7 22.0 6.5e-40 137.1 21.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OWF42870.1 - 0.0012 18.2 1.0 0.0012 18.2 1.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB YjcB PF15940.5 OWF42870.1 - 0.052 13.7 1.1 0.25 11.6 0.4 2.5 2 1 0 2 2 2 0 Family of unknown function DUF2897 PF11446.8 OWF42871.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PGM_PMM_I PF02878.16 OWF42872.1 - 2.5e-17 62.9 0.1 1.2e-07 31.5 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OWF42872.1 - 1.8e-12 47.2 0.7 3.7e-12 46.2 0.7 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OWF42872.1 - 0.0045 17.2 0.1 0.013 15.7 0.1 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OWF42872.1 - 0.17 12.5 1.0 2 9.1 1.0 2.8 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II RIG-I_C PF18119.1 OWF42873.1 - 6.5e-30 104.0 0.1 6.5e-30 104.0 0.1 3.3 4 0 0 4 4 4 1 RIG-I receptor C-terminal domain RIG-I_C-RD PF11648.8 OWF42873.1 - 2.6e-25 88.9 0.4 2.6e-25 88.9 0.4 2.7 3 0 0 3 3 3 1 C-terminal domain of RIG-I DEAD PF00270.29 OWF42873.1 - 1.7e-22 80.0 4.0 4.6e-22 78.6 0.6 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase CARD_2 PF16739.5 OWF42873.1 - 3.3e-22 78.3 1.5 3.4e-13 49.4 0.0 3.2 2 0 0 2 2 2 2 Caspase recruitment domain Helicase_C PF00271.31 OWF42873.1 - 5.8e-21 74.9 3.2 1.7e-20 73.4 0.1 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF42873.1 - 6.2e-21 75.1 2.0 1.1e-20 74.3 0.5 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CARD PF00619.21 OWF42873.1 - 6.7e-06 26.0 3.4 4.8e-05 23.3 0.0 3.8 4 0 0 4 4 4 1 Caspase recruitment domain Yippee-Mis18 PF03226.14 OWF42873.1 - 0.00015 22.0 4.8 0.00027 21.1 2.9 2.5 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_22 PF13401.6 OWF42873.1 - 0.00034 20.9 1.1 0.0021 18.3 0.4 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OWF42873.1 - 0.0053 17.1 0.3 0.073 13.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OWF42873.1 - 0.0065 16.2 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 OWF42873.1 - 0.014 15.1 0.0 0.046 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain zinc_ribbon_4 PF13717.6 OWF42873.1 - 0.019 14.9 0.8 3.8 7.5 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain NACHT PF05729.12 OWF42873.1 - 0.02 14.8 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain CARD_2 PF16739.5 OWF42874.1 - 1.3e-28 98.8 1.8 3.2e-16 59.1 0.0 3.6 3 0 0 3 3 3 2 Caspase recruitment domain DEAD PF00270.29 OWF42874.1 - 5.3e-21 75.2 0.2 1.4e-19 70.5 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase RIG-I_C PF18119.1 OWF42874.1 - 3e-20 72.7 1.2 3e-20 72.7 1.2 2.3 3 0 0 3 3 3 1 RIG-I receptor C-terminal domain ResIII PF04851.15 OWF42874.1 - 2.1e-18 66.9 0.4 3.9e-17 62.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OWF42874.1 - 5.4e-18 65.4 0.8 4.5e-17 62.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CARD PF00619.21 OWF42874.1 - 7.3e-14 51.6 2.2 7.5e-10 38.7 0.0 3.4 3 0 0 3 3 3 2 Caspase recruitment domain RIG-I_C-RD PF11648.8 OWF42874.1 - 4.1e-11 43.1 0.2 9.9e-11 41.9 0.2 1.7 1 0 0 1 1 1 1 C-terminal domain of RIG-I AAA_19 PF13245.6 OWF42874.1 - 0.0027 18.1 0.9 0.039 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF42874.1 - 0.091 12.5 0.0 2.8 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF678 PF05077.12 OWF42874.1 - 0.14 12.3 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF678) 7TM_GPCR_Srw PF10324.9 OWF42875.1 - 1.4e-35 123.1 21.9 1.7e-35 122.8 21.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF42875.1 - 1.9e-11 43.8 15.2 3.2e-11 43.1 15.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF42875.1 - 3.5e-06 26.8 16.6 3.5e-06 26.8 16.6 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4381 PF14316.6 OWF42875.1 - 0.25 11.6 0.1 0.25 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 OWF42875.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.4 2 1 1 3 3 3 0 TMEM154 protein family PspC PF04024.12 OWF42875.1 - 2.6 7.9 5.8 2.1 8.2 1.4 2.6 2 0 0 2 2 2 0 PspC domain Lamprin PF06403.11 OWF42877.1 - 1.5e-06 28.2 17.7 0.86 9.6 0.1 7.8 1 1 6 8 8 8 6 Lamprin DUF261 PF03196.13 OWF42877.1 - 0.0018 18.4 25.1 16 5.6 3.5 8.9 2 2 7 9 9 9 5 Protein of unknown function, DUF261 RecO_N PF11967.8 OWF42878.1 - 0.00046 20.1 5.0 9.1 6.3 0.1 5.1 4 1 1 5 5 5 1 Recombination protein O N terminal Pox_A3L PF05288.11 OWF42878.1 - 0.0022 18.0 0.0 70 3.5 0.0 4.7 2 1 3 5 5 5 0 Poxvirus A3L Protein PilM PF07419.12 OWF42878.1 - 0.042 14.0 2.9 11 6.2 0.1 3.7 1 1 3 4 4 4 0 PilM Tubulin_C PF03953.17 OWF42878.1 - 0.11 12.7 1.1 63 3.7 0.1 3.7 1 1 2 4 4 4 0 Tubulin C-terminal domain IreB PF06135.12 OWF42878.1 - 0.18 12.1 9.7 41 4.5 0.2 4.9 4 1 2 6 6 6 0 IreB regulatory phosphoprotein SAA PF00277.18 OWF42878.1 - 0.24 11.9 5.9 8.9 6.9 0.2 3.3 2 2 1 3 3 3 0 Serum amyloid A protein DUF2585 PF10755.9 OWF42878.1 - 1.3 8.7 8.0 35 4.1 0.0 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF2585) DUF4711 PF15829.5 OWF42879.1 - 0.071 13.1 6.9 37 4.2 0.0 6.5 2 1 8 10 10 10 0 Domain of unknown function (DUF4711) Glyco_hydro_63 PF03200.16 OWF42880.1 - 8.1e-211 701.0 4.0 1e-210 700.7 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OWF42880.1 - 8.2e-49 166.7 0.8 8.2e-49 166.7 0.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 OWF42880.1 - 0.011 14.6 1.1 0.025 13.5 1.1 1.6 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Actin PF00022.19 OWF42882.1 - 2.1e-108 362.5 0.0 8.6e-108 360.5 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OWF42882.1 - 0.099 11.4 0.0 9.6 4.9 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein SUFU_C PF12470.8 OWF42883.1 - 3.8e-71 239.4 0.0 4.9e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 OWF42883.1 - 9.9e-44 149.4 0.0 1.4e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) COMPASS-Shg1 PF05205.12 OWF42884.1 - 3.2e-21 76.0 0.1 3.2e-21 76.0 0.1 2.9 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DHO_dh PF01180.21 OWF42884.1 - 0.005 16.1 1.0 0.011 15.0 1.0 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase WD40 PF00400.32 OWF42885.1 - 3.4e-11 43.5 11.8 0.011 16.6 0.0 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat NACHT PF05729.12 OWF42885.1 - 3.5e-09 36.8 0.0 8.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 OWF42885.1 - 5.6e-05 23.4 0.3 3.5 8.0 0.1 5.5 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 OWF42885.1 - 6.1e-05 23.5 0.1 0.00038 20.9 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OWF42885.1 - 0.0026 17.7 0.8 0.032 14.2 0.0 3.2 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OWF42885.1 - 0.0062 16.8 0.0 0.021 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain BBS2_Mid PF14783.6 OWF42885.1 - 0.016 15.2 0.3 12 5.9 0.0 3.6 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region AAA_35 PF14516.6 OWF42885.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ResIII PF04851.15 OWF42885.1 - 0.072 13.1 0.5 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Lyase_8_C PF02884.17 OWF42886.1 - 0.00093 19.6 0.2 17 5.9 0.0 3.9 1 1 1 3 3 3 2 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DUF5074 PF16819.5 OWF42886.1 - 0.022 14.8 7.6 0.93 9.6 0.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5074) RAP PF08373.10 OWF42886.1 - 0.18 11.9 12.2 58 3.9 3.2 5.4 2 2 0 2 2 2 0 RAP domain RNA_pol_Rpb8 PF03870.15 OWF42887.1 - 0.35 11.0 6.4 78 3.5 0.2 4.0 1 1 2 4 4 4 0 RNA polymerase Rpb8 RCR PF12273.8 OWF42888.1 - 0.02 15.5 0.5 0.033 14.9 0.5 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TMEM132D_C PF15706.5 OWF42888.1 - 0.092 12.5 1.0 0.13 12.1 1.0 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 OWF42888.1 - 0.17 12.8 1.4 0.29 12.1 1.4 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EVC2_like PF12297.8 OWF42888.1 - 0.18 10.5 0.0 0.19 10.4 0.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CYYR1 PF10873.8 OWF42888.1 - 5.7 7.4 21.1 12 6.3 21.1 1.6 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Homeodomain PF00046.29 OWF42889.1 - 2.2e-21 75.5 1.1 4.1e-21 74.6 1.1 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF42889.1 - 0.032 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF42889.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain PHC2_SAM_assoc PF16616.5 OWF42889.1 - 0.79 10.5 4.2 1.6 9.6 0.7 2.4 2 1 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Noelin-1 PF12308.8 OWF42890.1 - 3 7.9 5.6 6.7 6.8 0.1 4.0 5 1 1 6 6 6 0 Neurogenesis glycoprotein SCA7 PF08313.12 OWF42892.1 - 0.24 11.3 2.1 84 3.2 0.6 4.5 3 1 2 5 5 5 0 SCA7, zinc-binding domain IrmA PF18673.1 OWF42892.1 - 4.3 7.5 18.7 16 5.7 0.8 6.0 1 1 5 6 6 6 0 interleukin receptor mimic protein A DUF4745 PF15923.5 OWF42892.1 - 7.3 6.6 14.8 4.5 7.3 0.1 3.8 2 1 1 4 4 4 0 Domain of unknown function (DUF4745) YcgR_2 PF12945.7 OWF42893.1 - 3.6 7.8 4.4 83 3.4 0.0 5.1 3 2 2 7 7 7 0 Flagellar protein YcgR Exo_endo_phos PF03372.23 OWF42895.1 - 8.6e-06 25.4 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0154 PF03672.13 OWF42895.1 - 0.011 15.8 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Haspin_kinase PF12330.8 OWF42896.1 - 4.3e-70 236.5 0.1 7.7e-70 235.7 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 OWF42896.1 - 1.7e-05 24.3 0.0 0.00017 21.1 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42896.1 - 0.019 14.3 0.0 0.93 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase PDEase_II PF02112.15 OWF42896.1 - 0.021 13.9 0.0 0.057 12.5 0.0 1.7 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Cnd2 PF05786.14 OWF42897.1 - 3e-130 436.3 21.7 4.1e-130 435.8 21.7 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 OWF42897.1 - 0.00039 20.6 1.4 0.001 19.3 0.6 2.1 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal MIEAP PF16026.5 OWF42898.1 - 2.3e-25 90.0 0.3 3.5e-25 89.4 0.3 1.2 1 0 0 1 1 1 1 Mitochondria-eating protein LRR_8 PF13855.6 OWF42899.1 - 1.8e-27 94.9 10.2 3.7e-15 55.4 2.1 3.2 2 1 1 3 3 3 2 Leucine rich repeat 7tm_2 PF00002.24 OWF42899.1 - 8.1e-14 51.5 10.4 2.5e-13 49.9 10.4 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) LRR_5 PF13306.6 OWF42899.1 - 8.9e-11 41.8 0.4 2.9e-10 40.2 0.4 1.8 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 OWF42899.1 - 2.6e-09 37.1 0.1 7.7e-09 35.6 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain GPS PF01825.21 OWF42899.1 - 1.5e-08 35.0 0.0 5.2e-08 33.3 0.0 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 OWF42899.1 - 2.5e-06 27.7 0.8 2.5e-06 27.7 0.8 4.3 5 0 0 5 5 4 2 Leucine Rich repeats (2 copies) GAIN PF16489.5 OWF42899.1 - 1.3e-05 24.8 0.4 2.2e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Ig_3 PF13927.6 OWF42899.1 - 3.2e-05 24.4 0.0 0.00016 22.2 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 OWF42899.1 - 3.7e-05 23.3 0.5 8.2e-05 22.2 0.5 1.5 1 0 0 1 1 1 1 Leucine-rich repeat I-set PF07679.16 OWF42899.1 - 5.8e-05 23.1 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF42899.1 - 9.6e-05 22.7 0.2 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 OWF42899.1 - 0.00013 22.1 0.8 3.7 8.4 0.0 4.9 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 OWF42899.1 - 0.00074 19.4 8.1 0.82 9.9 0.1 4.1 4 0 0 4 4 4 2 Leucine Rich repeat HRM PF02793.22 OWF42899.1 - 0.0013 19.0 0.3 0.0043 17.3 0.3 1.9 1 0 0 1 1 1 1 Hormone receptor domain LRRNT PF01462.18 OWF42899.1 - 0.29 10.8 4.4 0.21 11.2 0.8 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Carb_bind PF10645.9 OWF42900.1 - 9.9 6.5 15.6 53 4.1 0.5 5.1 1 1 4 5 5 5 0 Carbohydrate binding Glyco_hydro_59 PF02057.15 OWF42901.1 - 3e-117 391.1 2.8 4.3e-117 390.5 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 OWF42901.1 - 8.7e-44 148.4 0.0 1.4e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain DUF1749 PF08538.10 OWF42901.1 - 0.026 13.6 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Med28 PF11594.8 OWF42902.1 - 9.2e-11 42.0 0.3 1.4e-10 41.4 0.3 1.3 1 0 0 1 1 1 1 Mediator complex subunit 28 Sec2p PF06428.11 OWF42902.1 - 0.015 15.3 0.8 0.028 14.4 0.8 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DHHC PF01529.20 OWF42903.1 - 3.8e-30 104.7 11.1 3.8e-30 104.7 11.1 2.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 OWF42903.1 - 2.2 8.2 13.1 0.11 12.5 7.4 1.7 2 0 0 2 2 2 0 Ribosomal L40e family TssO PF17561.2 OWF42904.1 - 3.9 7.6 24.1 28 4.8 0.2 6.6 1 1 5 8 8 8 0 Type VI secretion system, TssO 7tm_1 PF00001.21 OWF42905.1 - 1.6e-62 211.3 20.4 1.9e-62 211.0 20.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF42905.1 - 5.7e-14 52.1 19.7 7.5e-14 51.7 19.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF42905.1 - 9.5e-05 22.1 22.1 9.5e-05 22.1 22.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Piezo_RRas_bdg PF12166.8 OWF42905.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain CitMHS PF03600.16 OWF42905.1 - 1.1 8.4 8.9 1.1 8.3 7.6 1.6 1 1 0 1 1 1 0 Citrate transporter 7tm_1 PF00001.21 OWF42906.1 - 1.6e-62 211.3 20.4 1.9e-62 211.0 20.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF42906.1 - 5.7e-14 52.1 19.7 7.5e-14 51.7 19.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF42906.1 - 9.5e-05 22.1 22.1 9.5e-05 22.1 22.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Piezo_RRas_bdg PF12166.8 OWF42906.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain CitMHS PF03600.16 OWF42906.1 - 1.1 8.4 8.9 1.1 8.3 7.6 1.6 1 1 0 1 1 1 0 Citrate transporter Xan_ur_permease PF00860.20 OWF42907.1 - 1.9e-57 194.8 23.7 1.3e-52 178.8 11.8 2.0 1 1 1 2 2 2 2 Permease family CoA_binding_3 PF13727.6 OWF42907.1 - 0.0013 18.8 2.2 0.12 12.3 0.2 2.9 2 1 0 2 2 2 2 CoA-binding domain Xan_ur_permease PF00860.20 OWF42908.1 - 2.4e-82 276.7 25.4 3.3e-82 276.3 25.4 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 OWF42908.1 - 2.1 8.8 16.6 2.9 8.3 2.7 3.8 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily hSac2 PF12456.8 OWF42909.1 - 1.1e-20 73.5 0.1 2.7e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Inositol phosphatase Syja_N PF02383.18 OWF42909.1 - 5.7e-14 52.2 0.4 1.1e-13 51.2 0.4 1.5 1 0 0 1 1 1 1 SacI homology domain Carb_anhydrase PF00194.21 OWF42910.1 - 1.7e-81 273.5 0.6 1.2e-76 257.7 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase DUF1433 PF07252.11 OWF42911.1 - 0.0061 16.8 42.6 22 5.4 2.3 8.2 1 1 5 6 6 6 5 Protein of unknown function (DUF1433) S_tail_recep_bd PF14928.6 OWF42912.1 - 0.2 12.3 1.6 14 6.3 0.1 3.1 1 1 2 3 3 3 0 Short tail fibre protein receptor-binding domain HARP PF07443.13 OWF42912.1 - 5.1 6.8 9.3 11 5.7 0.3 3.6 1 1 3 4 4 4 0 HepA-related protein (HARP) Gemin7 PF11095.8 OWF42916.1 - 2.9e-07 30.3 1.6 28 4.7 0.0 6.1 1 1 7 8 8 8 0 Gem-associated protein 7 (Gemin7) LepB_GAP_C PF18227.1 OWF42916.1 - 1.4e-05 25.5 11.3 1.5 9.4 1.5 5.3 1 1 3 4 4 4 3 LepB GAP domain C-terminal subdomain DDE_Tnp_1_7 PF13843.6 OWF42916.1 - 0.00073 18.9 6.9 1.9 7.7 0.5 4.5 1 1 3 4 4 4 3 Transposase IS4 Velvet PF11754.8 OWF42916.1 - 0.0022 18.0 4.1 0.16 11.9 0.1 4.2 1 1 2 3 3 3 1 Velvet factor DUF5372 PF17342.2 OWF42916.1 - 0.014 15.8 3.5 1.3e+02 3.1 0.1 4.3 1 1 8 9 9 9 0 Family of unknown function (DUF5372) DUF5358 PF17311.2 OWF42916.1 - 0.033 14.2 12.6 5.3 7.0 1.5 3.9 1 1 2 4 4 4 0 Family of unknown function (DUF5358) DUF4029 PF13221.6 OWF42916.1 - 0.059 14.0 8.9 85 3.9 0.2 5.2 1 1 8 9 9 9 0 Protein of unknown function (DUF4029) DUF4264 PF14084.6 OWF42916.1 - 0.57 9.9 18.4 69 3.2 0.2 6.2 1 1 9 10 10 10 0 Protein of unknown function (DUF4264) FbpC_C_terminal PF17845.1 OWF42917.1 - 0.015 15.4 0.0 16 5.7 0.0 3.1 3 0 0 3 3 3 0 FbpC C-terminal regulatory nucleotide binding domain PhyH PF05721.13 OWF42917.1 - 0.021 15.1 0.3 2.4 8.3 0.3 2.7 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) CX9C PF16860.5 OWF42917.1 - 2.7 8.1 7.9 34 4.6 0.1 3.1 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-RanBP PF00641.18 OWF42917.1 - 6.7 6.1 8.9 25 4.3 0.3 3.1 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-C2H2_4 PF13894.6 OWF42918.1 - 1.3e-08 34.9 8.8 0.00042 20.9 2.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF42918.1 - 2.3e-07 30.9 9.7 0.00094 19.5 1.0 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OWF42918.1 - 0.0013 18.5 5.8 0.0057 16.4 0.5 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type ADK_lid PF05191.14 OWF42918.1 - 0.0035 17.3 0.4 0.048 13.6 0.1 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid zf-met PF12874.7 OWF42918.1 - 0.0095 16.3 4.7 0.46 10.9 0.9 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF42918.1 - 0.019 15.3 3.3 0.53 10.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 OWF42918.1 - 0.027 14.5 0.5 0.041 13.9 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon GATA PF00320.27 OWF42918.1 - 0.041 13.5 0.2 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 GATA zinc finger C1_2 PF03107.16 OWF42918.1 - 0.051 13.9 4.5 3.6 8.0 0.1 2.1 1 1 1 2 2 2 0 C1 domain zf-ISL3 PF14690.6 OWF42918.1 - 0.085 13.5 2.2 0.12 13.1 2.2 1.4 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_2 PF13465.6 OWF42918.1 - 0.24 11.9 0.4 0.24 11.9 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double domain GAGA PF09237.11 OWF42918.1 - 0.27 11.0 5.4 2.1 8.2 0.2 2.4 1 1 1 2 2 2 0 GAGA factor DUF4764 PF15961.5 OWF42918.1 - 0.48 9.0 5.0 0.79 8.3 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) zf-met2 PF12907.7 OWF42918.1 - 0.61 10.3 7.6 1.4 9.1 2.6 2.4 2 0 0 2 2 2 0 Zinc-binding zf-C2HE PF16278.5 OWF42918.1 - 0.71 10.4 5.9 13 6.3 5.9 2.5 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 OWF42918.1 - 1.6 8.8 10.7 5.2 7.2 1.9 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 OWF42918.1 - 8.4 6.5 8.7 33 4.6 0.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger YqaJ PF09588.10 OWF42919.1 - 1.9e-08 34.6 0.0 3.9e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain Mg_trans_NIPA PF05653.14 OWF42920.1 - 2.7e-131 437.0 18.1 3.6e-131 436.7 18.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OWF42920.1 - 3.1e-05 24.1 5.0 3.1e-05 24.1 5.0 3.9 4 1 0 4 4 4 1 EamA-like transporter family DUF5383 PF17355.2 OWF42920.1 - 0.028 14.8 2.4 2 8.8 0.3 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) BatA PF07584.11 OWF42920.1 - 0.45 10.9 4.8 4.2 7.8 0.2 3.4 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal ST7 PF04184.12 OWF42920.1 - 2.3 6.6 4.5 3.7 5.9 4.5 1.2 1 0 0 1 1 1 0 ST7 protein Amidohydro_1 PF01979.20 OWF42921.1 - 9.4e-07 28.5 0.0 9.7e-07 28.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OWF42921.1 - 0.011 15.3 0.0 0.012 15.1 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase family Vitellogenin_N PF01347.22 OWF42922.1 - 3.3e-21 75.3 0.0 1e-19 70.4 0.0 2.3 1 1 0 1 1 1 1 Lipoprotein amino terminal region RNB PF00773.19 OWF42923.1 - 5.6e-89 298.7 0.1 2.5e-88 296.5 0.2 1.9 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 OWF42923.1 - 1.3e-21 76.4 0.0 2.9e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OWF42923.1 - 2e-08 34.3 0.1 3.1e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 OWF42923.1 - 5.8e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OWF42923.1 - 0.00049 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 S1 domain Myb_DNA-bind_4 PF13837.6 OWF42923.1 - 0.095 13.1 0.1 0.42 11.0 0.1 2.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Tautomerase PF01361.21 OWF42923.1 - 0.14 12.1 0.1 0.44 10.5 0.1 1.8 1 0 0 1 1 1 0 Tautomerase enzyme BSMAP PF12280.8 OWF42924.1 - 6.2e-49 166.8 0.5 9.8e-49 166.1 0.5 1.3 1 0 0 1 1 1 1 Brain specific membrane anchored protein Calreticulin PF00262.18 OWF42925.1 - 1.7e-83 280.5 19.8 5.1e-61 206.6 9.4 3.0 2 1 1 3 3 3 2 Calreticulin family RRM_1 PF00076.22 OWF42926.1 - 4.7e-20 71.2 0.1 6.2e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OWF42926.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OWF42926.1 - 0.2 11.8 0.0 0.5 10.5 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 OWF42927.1 - 1.6e-18 66.3 0.1 2.2e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OWF42927.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OWF42927.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif PID PF00640.23 OWF42928.1 - 3.8e-07 30.2 0.0 6.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Ctr PF04145.15 OWF42929.1 - 1.9e-18 67.5 16.2 4e-12 47.0 8.6 2.5 1 1 1 2 2 2 2 Ctr copper transporter family DUF1129 PF06570.11 OWF42929.1 - 0.0021 17.6 0.2 0.0036 16.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) GPI2 PF06432.11 OWF42929.1 - 0.026 14.0 4.3 0.042 13.3 3.8 1.5 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Ca_hom_mod PF14798.6 OWF42929.1 - 0.061 12.4 1.6 0.076 12.1 0.6 1.6 1 1 1 2 2 2 0 Calcium homeostasis modulator DUF3671 PF12420.8 OWF42929.1 - 2 8.5 5.2 66 3.6 5.2 2.5 1 1 0 1 1 1 0 Protein of unknown function Methyltransf_11 PF08241.12 OWF42930.1 - 2.2e-18 66.7 0.0 3.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF42930.1 - 1.8e-15 57.4 0.0 3.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF42930.1 - 9.1e-14 51.5 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF42930.1 - 2.8e-09 37.6 0.0 4.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF42930.1 - 3.5e-07 29.8 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF42930.1 - 1.2e-05 25.2 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF42930.1 - 0.0015 17.9 0.1 0.0034 16.7 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OWF42930.1 - 0.0031 17.5 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OWF42930.1 - 0.0037 16.9 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 OWF42930.1 - 0.0039 16.8 0.0 0.024 14.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OWF42930.1 - 0.0069 15.9 0.0 0.094 12.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.7 OWF42930.1 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OWF42930.1 - 0.037 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TM1506 PF08973.10 OWF42930.1 - 0.054 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) RNase_H_2 PF13482.6 OWF42930.1 - 0.072 13.1 0.1 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 RNase_H superfamily tRNA_U5-meth_tr PF05958.11 OWF42930.1 - 0.077 12.0 0.5 0.11 11.5 0.0 1.4 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.19 OWF42930.1 - 0.079 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 OWF42930.1 - 0.11 12.9 0.1 0.23 11.8 0.0 1.7 2 0 0 2 2 1 0 Predicted AdoMet-dependent methyltransferase HlyIII PF03006.20 OWF42931.1 - 3.9e-39 134.7 21.6 5.1e-39 134.3 21.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 OWF42931.1 - 2.4 8.3 8.3 0.17 12.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF962) HlyIII PF03006.20 OWF42932.1 - 2.1e-38 132.3 20.3 2.1e-38 132.3 20.3 1.9 3 0 0 3 3 3 1 Haemolysin-III related Adeno_E3 PF06040.11 OWF42932.1 - 0.0048 17.1 2.6 0.088 13.0 0.0 3.0 3 0 0 3 3 3 1 Adenovirus E3 protein Reeler PF02014.16 OWF42934.1 - 1.6e-17 64.5 0.0 2.6e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Reeler domain Cytochrom_B561 PF03188.16 OWF42934.1 - 1.3e-07 31.8 2.8 1.3e-07 31.8 2.8 2.1 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OWF42934.1 - 0.0003 21.0 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Ninjurin PF04923.12 OWF42934.1 - 0.47 10.4 1.8 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Ninjurin DUF4079 PF13301.6 OWF42934.1 - 1.4 9.1 8.0 5.3 7.2 5.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) STAS PF01740.21 OWF42935.1 - 3.5e-19 68.5 0.0 4.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OWF42935.1 - 0.017 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 STAS domain DUF1744 PF08490.12 OWF42935.1 - 0.022 13.3 0.2 0.042 12.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1744) Sulfate_transp PF00916.20 OWF42936.1 - 7.3e-96 321.2 24.9 1e-95 320.7 24.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OWF42936.1 - 4.9e-22 77.8 0.3 1.5e-21 76.2 0.1 1.9 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 OWF42936.1 - 0.022 15.1 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 STAS domain DUF1744 PF08490.12 OWF42936.1 - 0.066 11.8 0.2 0.12 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Methyltransf_25 PF13649.6 OWF42937.1 - 0.00023 21.8 0.0 0.0006 20.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FMO-like PF00743.19 OWF42938.1 - 6.6e-77 259.1 1.6 7.4e-77 259.0 1.6 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF42938.1 - 4.5e-16 59.0 0.0 6.9e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF42938.1 - 1.9e-11 43.8 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF42938.1 - 1.9e-11 43.7 0.0 1.5e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OWF42938.1 - 5.9e-05 23.2 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OWF42938.1 - 0.00095 19.2 0.1 1.2 9.1 0.0 2.3 1 1 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OWF42938.1 - 0.014 15.5 0.1 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mqo PF06039.15 OWF42938.1 - 0.022 13.3 0.1 0.039 12.5 0.1 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) AlaDh_PNT_C PF01262.21 OWF42938.1 - 0.031 13.6 0.2 0.06 12.6 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OWF42938.1 - 0.032 13.5 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 OWF42938.1 - 0.042 13.4 0.0 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OWF42938.1 - 0.053 14.0 1.4 5.5 7.5 0.2 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding Phlebovirus_NSM PF07246.11 OWF42938.1 - 0.055 12.8 0.1 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Peptidase_M17_N PF02789.17 OWF42938.1 - 0.058 13.3 1.4 0.06 13.2 0.1 1.6 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain FAD_binding_2 PF00890.24 OWF42938.1 - 0.059 12.4 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OWF42938.1 - 0.15 11.2 0.2 0.67 9.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OWF42938.1 - 0.19 12.3 1.7 48 4.6 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OWF42939.1 - 4.9e-85 285.9 0.0 5.9e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF42939.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C2H2 PF00096.26 OWF42940.1 - 2.6e-10 40.2 22.7 0.0023 18.3 2.7 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF42940.1 - 8e-09 35.1 17.9 1.7e-07 30.8 4.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OWF42940.1 - 1.5e-06 28.6 18.2 0.023 15.5 0.8 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF42940.1 - 3.2e-05 24.1 20.3 0.0035 17.7 0.0 4.6 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 OWF42940.1 - 0.016 15.5 12.2 0.17 12.3 5.4 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OWF42940.1 - 0.022 15.1 16.4 0.041 14.2 2.9 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 OWF42940.1 - 0.071 11.6 6.8 0.52 8.8 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF629) NCE101 PF11654.8 OWF42940.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 zf-C2H2_7 PF15269.6 OWF42940.1 - 0.27 11.3 5.5 0.075 13.1 0.7 2.7 3 0 0 3 3 2 0 Zinc-finger zf-met2 PF12907.7 OWF42940.1 - 0.28 11.3 4.8 12 6.1 0.0 2.8 2 0 0 2 2 2 0 Zinc-binding zf_C2H2_ZHX PF18387.1 OWF42940.1 - 0.42 10.3 11.5 7.3 6.3 0.1 3.6 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 OWF42940.1 - 0.48 10.9 13.4 1.1 9.7 0.3 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 OWF42940.1 - 0.59 10.1 4.4 0.37 10.7 0.4 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rpr2 PF04032.16 OWF42940.1 - 0.61 10.4 4.3 6.8 7.1 1.8 3.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf_Hakai PF18408.1 OWF42940.1 - 1.9 8.3 4.9 0.5 10.1 0.6 2.1 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain Mon1 PF03164.14 OWF42941.1 - 1.5e-08 34.2 0.0 4e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Trafficking protein Mon1 CLASP_N PF12348.8 OWF42942.1 - 3.1e-28 98.9 17.7 1.6e-09 37.7 0.0 7.2 7 2 1 8 8 8 5 CLASP N terminal HEAT PF02985.22 OWF42942.1 - 1.6e-12 46.5 6.5 0.25 11.7 0.1 9.3 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 OWF42942.1 - 3.5e-11 43.4 0.8 0.024 15.0 0.0 8.8 10 1 0 10 10 10 2 HEAT repeats HEAT_EZ PF13513.6 OWF42942.1 - 5.9e-08 33.1 4.4 0.036 14.6 0.0 6.9 6 1 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 OWF42942.1 - 2.5e-07 30.9 15.3 0.59 10.2 0.1 7.7 5 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OWF42942.1 - 3.6e-05 24.3 4.2 27 5.4 0.0 7.5 7 1 1 8 8 7 0 Vacuolar 14 Fab1-binding region RasGEF_N_2 PF14663.6 OWF42942.1 - 0.00094 19.6 1.3 26 5.3 0.3 5.1 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MMS19_N PF14500.6 OWF42942.1 - 0.033 13.8 6.0 34 3.9 0.0 6.0 5 1 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 OWF42942.1 - 0.04 14.1 13.7 12 6.0 0.5 7.9 9 3 1 10 10 10 0 Telomere-length maintenance and DNA damage repair Tti2 PF10521.9 OWF42942.1 - 0.07 12.7 4.8 14 5.1 0.0 4.9 5 0 0 5 5 5 0 Tti2 family ACDC PF14733.6 OWF42942.1 - 0.11 12.9 1.0 0.82 10.0 0.3 2.8 2 0 0 2 2 2 0 AP2-coincident C-terminal SHS2_Rpb7-N PF03876.17 OWF42943.1 - 1.6e-07 31.6 0.0 4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 OWF42943.1 - 8.3e-05 23.2 0.0 8.3e-05 23.2 0.0 4.1 3 2 1 4 4 4 2 RPA43 OB domain in RNA Pol I Hid1 PF12722.7 OWF42943.1 - 5.8 4.9 5.1 7.4 4.6 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TPR_1 PF00515.28 OWF42944.1 - 2.6e-44 147.3 36.7 1.3e-05 24.8 0.0 13.7 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42944.1 - 3.8e-42 139.0 31.4 4.6e-05 23.2 0.1 15.8 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_8 PF13181.6 OWF42944.1 - 4.5e-38 126.3 19.0 0.0016 18.5 0.0 13.1 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 OWF42944.1 - 8.7e-35 119.1 5.5 2.4e-05 24.7 0.0 10.5 9 3 2 11 11 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 OWF42944.1 - 1.2e-34 116.0 10.5 0.00068 20.3 0.0 12.5 9 2 3 12 12 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 OWF42944.1 - 1.5e-28 99.2 14.5 4.4e-06 27.2 0.2 9.5 8 3 2 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 OWF42944.1 - 9.5e-27 93.1 26.1 1.6e-07 31.5 5.0 9.7 6 4 2 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.6 OWF42944.1 - 7.8e-21 72.9 25.4 0.2 12.1 0.0 16.1 17 1 0 17 17 16 4 Tetratricopeptide repeat TPR_11 PF13414.6 OWF42944.1 - 2.6e-20 71.8 18.1 0.0001 21.9 0.0 12.3 13 0 0 13 13 13 3 TPR repeat TPR_6 PF13174.6 OWF42944.1 - 5.4e-19 67.5 26.0 0.038 14.6 0.3 12.9 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF42944.1 - 1.5e-18 65.4 22.8 0.0025 17.7 0.1 11.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_10 PF13374.6 OWF42944.1 - 1.4e-17 62.9 29.2 0.0052 16.6 0.1 11.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 OWF42944.1 - 2e-09 37.5 4.2 0.0096 16.1 0.0 6.7 5 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF42944.1 - 5.8e-06 26.4 32.3 0.043 14.0 0.0 7.4 6 1 2 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 OWF42944.1 - 7.6e-05 22.5 13.4 0.4 10.4 0.3 5.2 2 2 3 5 5 5 3 Tetratricopeptide repeat-like domain NARP1 PF12569.8 OWF42944.1 - 0.00012 21.2 3.3 0.00012 21.2 3.3 5.1 4 2 1 5 5 3 1 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 OWF42944.1 - 0.0017 17.2 0.1 0.68 8.6 0.0 3.3 2 1 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 OWF42944.1 - 0.0022 18.5 8.3 24 5.9 0.1 6.2 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF42944.1 - 0.0031 17.6 16.1 13 5.9 0.1 7.0 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.9 OWF42944.1 - 0.013 15.5 10.7 1.2 9.3 0.0 5.6 5 1 1 6 6 6 0 Rapsyn N-terminal myristoylation and linker region RNA_pol_Rpb6 PF01192.22 OWF42944.1 - 0.079 12.9 1.4 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb6 Wzy_C_2 PF11846.8 OWF42944.1 - 0.8 9.6 0.0 0.8 9.6 0.0 3.2 4 0 0 4 4 3 0 Virulence factor membrane-bound polymerase, C-terminal TPPII_N PF12583.8 OWF42944.1 - 3.4 8.2 8.9 1.3 9.6 0.1 3.8 4 1 1 5 5 4 0 Tripeptidyl peptidase II N terminal RA PF00788.23 OWF42946.1 - 1.2e-08 35.5 0.2 6.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain GAS PF13851.6 OWF42946.1 - 0.13 11.6 30.0 0.041 13.2 18.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding zf-RING_2 PF13639.6 OWF42947.1 - 2e-09 37.6 14.7 2e-09 37.6 14.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF42947.1 - 8.6e-09 35.1 12.6 8.6e-09 35.1 12.6 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF42947.1 - 2.3e-07 30.5 11.3 4.8e-07 29.5 11.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF42947.1 - 5.5e-06 26.6 8.9 1.4e-05 25.3 8.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OWF42947.1 - 9.9e-06 25.3 13.3 1.8e-05 24.4 13.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF42947.1 - 1.7e-05 24.6 15.4 1.7e-05 24.6 15.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF42947.1 - 9.5e-05 22.3 9.4 0.0002 21.3 9.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF42947.1 - 0.0019 18.1 13.5 0.0019 18.1 13.5 2.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-C4H2 PF10146.9 OWF42947.1 - 0.026 14.8 3.0 0.042 14.1 3.0 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein zf-ANAPC11 PF12861.7 OWF42947.1 - 0.036 14.1 3.9 0.074 13.1 3.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OWF42947.1 - 1.7 8.9 14.3 11 6.3 14.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Filament PF00038.21 OWF42948.1 - 2.4e-25 89.8 54.2 7.4e-25 88.2 54.2 1.9 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 OWF42948.1 - 3.1e-13 50.0 0.0 7.6e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Lamin Tail Domain DUF2935 PF11155.8 OWF42948.1 - 3.8e-05 24.0 2.4 1.1 9.5 0.2 4.0 1 1 1 3 3 3 3 Domain of unknown function (DUF2935) Spc7 PF08317.11 OWF42948.1 - 0.0022 16.9 13.5 0.0022 16.9 13.5 3.2 1 1 2 3 3 3 2 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 OWF42948.1 - 3.9 7.8 24.6 2.6 8.4 0.3 5.2 4 1 1 5 5 5 0 ABC transporter C-terminal domain zf-RING_2 PF13639.6 OWF42949.1 - 3.5e-11 43.2 9.4 3.5e-11 43.2 9.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OWF42949.1 - 6e-08 32.8 7.4 6e-08 32.8 7.4 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF42949.1 - 1.1e-06 28.3 9.3 1.1e-06 28.3 9.3 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF42949.1 - 1.8e-06 27.6 7.9 1.8e-06 27.6 7.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF42949.1 - 2e-06 27.6 9.8 2e-06 27.6 9.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF42949.1 - 6.2e-06 26.1 7.0 1.5e-05 24.9 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF42949.1 - 0.00024 20.9 6.5 0.00054 19.8 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF42949.1 - 0.00061 19.8 5.5 0.00061 19.8 5.5 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF42949.1 - 0.0014 18.6 3.5 0.003 17.6 3.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OWF42949.1 - 0.13 12.5 5.4 0.36 11.0 5.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 OWF42949.1 - 0.19 11.9 9.0 0.63 10.2 9.0 2.0 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 OWF42949.1 - 0.68 9.8 12.2 0.065 13.1 7.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OWF42949.1 - 3.2 7.5 6.3 7.9 6.2 6.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MIB_HERC2 PF06701.13 OWF42950.1 - 2.2e-16 59.8 10.2 3.5e-11 43.2 3.8 3.2 3 0 0 3 3 3 2 Mib_herc2 DUF4314 PF14192.6 OWF42950.1 - 0.18 11.7 0.2 0.18 11.7 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) WWE PF02825.20 OWF42950.1 - 0.53 10.9 3.6 0.32 11.6 0.9 2.1 2 0 0 2 2 2 0 WWE domain ShK PF01549.24 OWF42951.1 - 4.2 8.0 11.7 1.1 9.9 6.1 2.4 2 0 0 2 2 2 0 ShK domain-like DUF4670 PF15709.5 OWF42952.1 - 4.5e-11 42.8 142.3 4.5e-11 42.8 142.3 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4670) Acyl_transf_3 PF01757.22 OWF42953.1 - 1.5e-26 93.3 30.1 1.5e-26 93.3 30.1 1.5 2 0 0 2 2 2 1 Acyltransferase family Transposase_28 PF04195.12 OWF42953.1 - 0.029 14.6 2.8 0.11 12.7 0.1 3.0 3 0 0 3 3 3 0 Putative gypsy type transposon NP1-WLL PF11733.8 OWF42953.1 - 0.47 10.2 1.1 0.79 9.5 1.1 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Guanylate_cyc PF00211.20 OWF42954.1 - 1.6e-55 187.6 0.0 2.5e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 OWF42954.1 - 1.2e-28 101.1 0.1 2e-28 100.4 0.1 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 OWF42954.1 - 1.2e-07 31.5 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Heme NO binding associated DUF668 PF05003.12 OWF42954.1 - 0.012 16.0 0.1 9.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF668) Alk_phosphatase PF00245.20 OWF42955.1 - 7e-134 446.9 4.6 8.3e-134 446.6 4.6 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF42955.1 - 5.1e-06 26.0 0.0 7.9e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily HTH_3 PF01381.22 OWF42955.1 - 0.13 12.4 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix C1q PF00386.21 OWF42956.1 - 1.1e-06 28.9 0.2 8.8e-06 25.9 0.2 2.1 1 1 0 1 1 1 1 C1q domain Wzt_C PF14524.6 OWF42956.1 - 0.021 14.9 0.1 0.82 9.7 0.0 2.3 1 1 1 2 2 2 0 Wzt C-terminal domain 7tm_1 PF00001.21 OWF42957.1 - 9.6e-21 74.3 18.0 1.3e-20 73.9 18.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF42957.1 - 1e-08 35.1 12.1 1.2e-08 34.9 10.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Collagen PF01391.18 OWF42958.1 - 0.00043 20.0 3.1 0.00072 19.3 3.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 6PGD PF00393.19 OWF42959.1 - 3.3e-128 427.1 0.0 5.4e-128 426.4 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OWF42959.1 - 1.2e-49 168.5 0.1 1.7e-49 168.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OWF42959.1 - 0.0025 17.9 0.4 0.0067 16.5 0.4 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OWF42959.1 - 0.049 14.2 0.5 0.11 13.1 0.3 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DNA_pol3_beta PF00712.19 OWF42959.1 - 0.059 13.5 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain PGK PF00162.19 OWF42959.1 - 0.068 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase NAD_binding_11 PF14833.6 OWF42959.1 - 0.078 13.2 0.5 0.68 10.2 0.1 2.3 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase FtsJ PF01728.19 OWF42959.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase IlvN PF07991.12 OWF42959.1 - 0.17 11.5 0.2 0.68 9.5 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 OWF42959.1 - 0.2 11.0 0.5 0.4 10.0 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Astacin PF01400.24 OWF42960.1 - 4.9e-41 140.4 1.0 4.9e-41 140.4 1.0 1.9 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.20 OWF42960.1 - 3e-09 37.2 0.3 2.6e-08 34.2 0.0 2.6 2 1 1 3 3 3 1 CUB domain EGF PF00008.27 OWF42960.1 - 8.3e-06 26.0 6.9 8.3e-06 26.0 6.9 3.4 3 0 0 3 3 3 2 EGF-like domain Cornifin PF02389.15 OWF42962.1 - 3.8e-08 33.6 9.9 0.00011 22.5 0.0 2.0 1 1 1 2 2 2 2 Cornifin (SPRR) family RIH_assoc PF08454.11 OWF42963.1 - 6.5e-37 125.4 13.2 1.9e-35 120.7 1.9 4.3 3 0 0 3 3 3 2 RyR and IP3R Homology associated Ion_trans PF00520.31 OWF42963.1 - 9e-19 67.7 10.8 1.8e-18 66.7 10.8 1.5 1 0 0 1 1 1 1 Ion transport protein RYDR_ITPR PF01365.21 OWF42963.1 - 2.9e-10 39.9 4.6 2.9e-10 39.9 4.6 4.2 5 1 0 5 5 5 1 RIH domain CC2-LZ PF16516.5 OWF42963.1 - 0.1 13.0 3.1 0.5 10.8 3.1 2.2 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Sec2p PF06428.11 OWF42963.1 - 0.12 12.3 11.5 0.043 13.8 6.8 2.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p FlxA PF14282.6 OWF42963.1 - 1.8 8.6 9.3 2 8.5 6.4 2.6 2 0 0 2 2 2 0 FlxA-like protein MscS_porin PF12795.7 OWF42963.1 - 6.1 6.3 11.9 0.21 11.1 5.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain RYDR_ITPR PF01365.21 OWF42964.1 - 6.3e-45 153.1 3.6 7.7e-45 152.8 3.6 1.1 1 0 0 1 1 1 1 RIH domain Vps35 PF03635.17 OWF42964.1 - 0.00016 20.3 1.6 0.00018 20.2 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 ACCA PF03255.14 OWF42964.1 - 0.075 12.9 0.7 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MIR PF02815.19 OWF42965.1 - 6.6e-67 225.0 0.1 8.6e-63 211.5 0.0 2.2 2 0 0 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 OWF42965.1 - 1.1e-64 217.6 0.0 1.2e-62 210.9 0.0 2.3 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 OWF42965.1 - 0.00097 18.6 0.3 0.0018 17.7 0.3 1.5 1 0 0 1 1 1 1 RIH domain Mucin_bdg PF03272.13 OWF42965.1 - 0.06 13.4 0.3 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module CBM_14 PF01607.24 OWF42966.1 - 1.2e-13 51.0 28.1 3.9e-07 30.1 5.2 3.8 4 0 0 4 4 4 3 Chitin binding Peritrophin-A domain APA3_viroporin PF11289.8 OWF42966.1 - 0.1 12.1 0.1 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Coronavirus accessory protein 3a CBM_14 PF01607.24 OWF42967.1 - 1.4e-12 47.6 24.7 3.8e-06 26.9 2.5 3.9 3 1 1 4 4 4 3 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF42968.1 - 1.6e-12 47.4 20.8 1.6e-06 28.1 1.4 4.0 3 1 1 4 4 4 3 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF42969.1 - 2e-09 37.5 18.2 0.00013 22.1 2.8 3.9 3 1 1 4 4 4 3 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF42970.1 - 7.9e-12 45.2 15.8 8.7e-07 29.0 2.1 2.9 2 1 1 3 3 3 2 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF42971.1 - 2e-09 37.5 26.5 2.7e-05 24.2 1.8 4.4 3 1 0 4 4 4 3 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF42972.1 - 1.5e-13 50.6 20.4 8.2e-07 29.1 4.4 3.6 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Defensin_beta PF00711.19 OWF42972.1 - 0.15 12.1 5.5 0.53 10.4 2.6 3.2 2 0 0 2 2 2 0 Beta defensin NAPRTase PF04095.16 OWF42973.1 - 1.5e-70 237.6 0.0 2.9e-70 236.6 0.0 1.5 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 OWF42973.1 - 2.8e-41 139.9 0.1 5.5e-41 139.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) Glyco_hydro_1 PF00232.18 OWF42975.1 - 0.00028 19.4 1.2 1.7 7.0 0.1 3.0 1 1 2 3 3 3 3 Glycosyl hydrolase family 1 VAPB_antitox PF02697.14 OWF42975.1 - 0.00045 20.9 0.0 31 5.4 0.0 4.0 1 1 4 5 5 5 0 Putative antitoxin GFRP PF06399.13 OWF42975.1 - 0.013 15.3 0.0 10 6.1 0.0 2.8 1 1 3 4 4 4 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF3698 PF12479.8 OWF42975.1 - 0.015 15.8 0.0 37 4.9 0.0 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3698) WRNPLPNID PF15017.6 OWF42975.1 - 0.021 15.7 7.1 4.3e+02 1.9 0.0 6.4 7 0 0 7 7 7 0 Putative WW-binding domain and destruction box DFRP_C PF16543.5 OWF42975.1 - 0.35 11.4 9.3 74 3.9 0.2 4.5 1 1 6 7 7 7 0 DRG Family Regulatory Proteins, Tma46 Pkinase_Tyr PF07714.17 OWF42976.1 - 0.033 13.5 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Formyl_trans_N PF00551.19 OWF42978.1 - 2.3 7.9 7.9 0.78 9.5 4.2 1.9 1 1 1 2 2 2 0 Formyl transferase GRDP-like PF07173.12 OWF42979.1 - 1.4e-49 168.4 6.3 2e-39 135.5 1.3 3.2 1 1 2 3 3 3 3 Glycine-rich domain-containing protein-like Pkinase PF00069.25 OWF42980.1 - 4.3e-64 216.4 0.3 7.1e-64 215.7 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF42980.1 - 1.5e-46 158.8 0.2 2.3e-46 158.2 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OWF42980.1 - 1.8e-19 69.9 4.7 4.1e-19 68.7 0.2 3.0 2 1 1 3 3 3 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OWF42980.1 - 7.4e-06 25.0 0.8 1.3e-05 24.2 0.5 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OWF42980.1 - 8.7e-06 25.2 0.1 1.2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF42980.1 - 0.003 16.5 0.3 0.0044 16.0 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF42980.1 - 0.011 15.7 0.1 0.076 12.9 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dynamin_N PF00350.23 OWF42981.1 - 7.3e-17 61.9 0.3 1.1e-15 58.0 0.0 3.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF42981.1 - 6.2e-05 23.0 0.0 0.00068 19.7 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OWF42981.1 - 0.0021 18.6 0.0 0.047 14.2 0.0 3.6 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OWF42981.1 - 0.0034 17.7 0.0 0.018 15.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OWF42981.1 - 0.013 15.4 0.2 0.084 12.8 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 OWF42981.1 - 0.062 13.1 0.2 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiN PF02553.15 OWF42981.1 - 0.19 11.7 0.0 0.82 9.7 0.0 2.1 1 0 0 1 1 1 0 Cobalt transport protein component CbiN SET PF00856.28 OWF42982.1 - 9.8e-15 55.3 0.4 1.2e-13 51.8 0.4 2.4 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 OWF42982.1 - 3.9e-14 51.8 3.8 0.00043 20.0 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF42982.1 - 6.3e-13 47.8 2.3 0.036 14.2 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF42982.1 - 6.2e-12 45.8 0.1 1.5e-05 25.4 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat zf-MYND PF01753.18 OWF42982.1 - 8.6e-11 41.7 30.5 5.2e-07 29.6 15.8 3.1 2 1 0 2 2 2 2 MYND finger TPR_8 PF13181.6 OWF42982.1 - 8.7e-09 34.9 4.1 0.46 10.8 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF42982.1 - 7.1e-08 32.6 1.1 3.2e-07 30.5 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OWF42982.1 - 1.5e-07 32.0 0.3 0.0065 17.1 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF42982.1 - 9.2e-07 28.5 0.1 2.1 8.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF42982.1 - 2.2e-05 24.4 1.4 4.6 7.4 0.1 4.4 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 OWF42982.1 - 7e-05 23.3 0.4 12 7.0 0.2 4.9 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OWF42982.1 - 7.9e-05 22.3 0.3 8.3 6.2 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.6 OWF42982.1 - 0.00069 19.8 0.0 37 5.0 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF42982.1 - 0.0014 18.9 0.6 35 4.8 0.0 5.0 4 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 OWF42982.1 - 0.0016 18.5 2.9 4.4 7.4 0.1 3.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 OWF42982.1 - 0.0039 17.3 0.1 4.6 7.5 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 OWF42982.1 - 0.016 15.2 5.0 13 5.9 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3485 PF11984.8 OWF42982.1 - 0.051 13.3 0.1 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3485) TPR_6 PF13174.6 OWF42982.1 - 0.15 12.7 1.6 21 6.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat SAF PF08666.12 OWF42982.1 - 0.17 12.5 0.0 9.1 7.0 0.0 2.7 2 0 0 2 2 2 0 SAF domain DUF1640 PF07798.11 OWF42983.1 - 2.4e-51 174.3 12.1 3e-51 174.0 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2935 PF11155.8 OWF42983.1 - 0.88 9.9 6.1 17 5.8 4.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) UQ_con PF00179.26 OWF42984.1 - 7.8e-45 152.0 0.0 1e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF42984.1 - 0.0013 19.0 0.1 0.0021 18.4 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 OWF42984.1 - 0.0038 17.1 0.0 0.0066 16.3 0.0 1.4 1 1 0 1 1 1 1 UEV domain Lipase_GDSL_2 PF13472.6 OWF42986.1 - 1.5e-05 25.5 0.0 1.6e-05 25.4 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SMYLE_N PF18615.1 OWF42987.1 - 7.6e-08 32.3 6.8 1.5e-06 28.1 0.2 2.6 2 0 0 2 2 2 2 Short myomegalin-like EB1 binding proteins, N-terminal domain zf-AD PF07776.15 OWF42987.1 - 2e-07 31.1 5.6 5.2e-07 29.8 1.1 3.0 3 0 0 3 3 3 1 Zinc-finger associated domain (zf-AD) zf-C2H2_3rep PF18868.1 OWF42987.1 - 0.011 16.4 0.6 11 6.7 0.1 3.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 OWF42987.1 - 0.083 13.8 0.2 0.083 13.8 0.2 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-Di19 PF05605.12 OWF42987.1 - 0.087 13.1 1.1 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OWF42987.1 - 0.12 12.9 0.3 0.12 12.9 0.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type CPL PF08144.11 OWF42987.1 - 0.18 12.2 4.2 0.41 11.0 4.2 1.6 1 0 0 1 1 1 0 CPL (NUC119) domain Cas_CXXC_CXXC PF09706.10 OWF42987.1 - 0.72 10.1 3.5 0.67 10.2 0.1 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-C2H2_2 PF12756.7 OWF42987.1 - 0.74 10.2 6.0 1.1 9.7 0.2 3.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.12 OWF42987.1 - 1 9.9 5.3 5.3 7.6 2.0 2.8 2 0 0 2 2 2 0 CHY zinc finger zf-BED PF02892.15 OWF42987.1 - 2.7 8.1 7.4 6.6 6.8 0.3 3.7 3 0 0 3 3 3 0 BED zinc finger CS PF04969.16 OWF42988.1 - 3.2e-10 40.9 0.1 4.2e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 OWF42988.1 - 0.023 15.1 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 PIH1 CS-like domain Ribosomal_L21p PF00829.21 OWF42989.1 - 3.7e-18 65.6 0.2 6.1e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Herpes_gI PF01688.17 OWF42989.1 - 0.089 12.7 0.0 56 3.6 0.0 3.4 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein I PNGaseA PF12222.8 OWF42989.1 - 0.095 11.5 0.0 6 5.6 0.0 2.4 3 0 0 3 3 3 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Toxin_12 PF07740.12 OWF42991.1 - 0.0063 17.2 6.3 0.01 16.5 6.3 1.4 1 0 0 1 1 1 1 Ion channel inhibitory toxin DUF5637 PF18687.1 OWF42991.1 - 4.5 7.3 14.3 11 6.1 7.3 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5637) DUF4552 PF15089.6 OWF42992.1 - 0.12 11.4 42.2 1.5 7.8 1.3 8.4 1 1 8 10 10 10 0 Domain of unknown function (DUF4552) DUF3972 PF13118.6 OWF42993.1 - 4.9e-07 30.2 1.2 1.2 9.6 0.0 4.2 1 1 3 4 4 4 2 Protein of unknown function (DUF3972) DUF2564 PF10819.8 OWF42993.1 - 3.2e-06 27.4 20.5 0.14 12.6 0.2 7.9 1 1 4 6 6 6 4 Protein of unknown function (DUF2564) DUF4818 PF16089.5 OWF42993.1 - 0.00047 20.6 4.8 6.2 7.3 0.2 4.3 1 1 4 5 5 5 1 Domain of unknown function (DUF4818) HrpE PF06188.12 OWF42993.1 - 0.00098 19.0 7.8 0.97 9.3 0.2 3.3 1 1 2 3 3 3 3 HrpE/YscL/FliH and V-type ATPase subunit E L27_1 PF09058.10 OWF42993.1 - 0.0017 18.3 2.7 34 4.5 0.0 6.0 1 1 4 5 5 5 0 L27_1 DUF445 PF04286.12 OWF42993.1 - 0.004 17.0 0.4 0.0074 16.1 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF445) BAR PF03114.18 OWF42993.1 - 0.0068 16.1 8.1 0.21 11.2 1.0 3.3 1 1 1 3 3 3 2 BAR domain PspA_IM30 PF04012.12 OWF42993.1 - 0.016 14.8 3.3 6.1 6.4 0.3 3.9 1 1 2 3 3 3 0 PspA/IM30 family DUF4107 PF13389.6 OWF42993.1 - 0.03 14.5 14.2 6.5 6.9 0.6 5.2 1 1 5 6 6 6 0 Protein of unknown function (DUF4107) DUF1978 PF09321.10 OWF42993.1 - 0.04 13.2 2.0 22 4.2 0.0 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF1978) RE_MjaI PF09568.10 OWF42993.1 - 0.15 11.8 8.1 34 4.2 0.1 4.8 1 1 5 6 6 6 0 MjaI restriction endonuclease NopRA1 PF16201.5 OWF42993.1 - 0.25 10.9 18.4 33 4.0 0.5 6.0 1 1 2 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 H2O2_YaaD PF03883.14 OWF42993.1 - 0.49 9.9 6.3 7.2 6.1 0.4 3.4 1 1 1 2 2 2 0 Peroxide stress protein YaaA RPA PF10134.9 OWF42993.1 - 2.1 7.8 5.4 6 6.3 0.3 3.0 1 1 3 4 4 4 0 Replication initiator protein A Cys_box PF17869.1 OWF42993.1 - 3.9 7.7 32.8 12 6.1 1.9 4.5 1 1 5 6 6 6 0 Anosmin cysteine rich domain MFS_1 PF07690.16 OWF42994.1 - 6.9e-44 150.2 25.6 1.2e-32 113.3 11.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF42994.1 - 1.6e-43 149.3 14.1 1.6e-34 119.6 3.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 OWF42994.1 - 2.5e-09 36.9 14.4 4.1e-08 32.9 1.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OWF42994.1 - 1.9e-08 33.1 5.2 4.8e-06 25.2 2.6 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 OWF42994.1 - 0.00011 21.3 15.5 0.023 13.6 5.4 2.3 2 0 0 2 2 2 2 MFS_1 like family Col_cuticle_N PF01484.17 OWF42994.1 - 1.6 8.8 4.7 5.9 7.0 0.1 3.6 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain SH3_9 PF14604.6 OWF42996.1 - 5.4e-20 71.0 6.2 3.1e-07 30.1 0.2 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 OWF42996.1 - 1.7e-18 66.0 2.2 1.5e-05 24.5 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 OWF42996.1 - 7.2e-12 44.8 1.9 0.0048 16.6 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 OWF42996.1 - 0.0011 19.2 9.5 1.3 9.4 0.3 4.5 4 0 0 4 4 4 2 Bacterial SH3 domain SH3_16 PF18348.1 OWF42996.1 - 0.28 11.0 2.7 6.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF2981 PF11200.8 OWF42996.1 - 4.5 6.9 7.7 1.9 8.2 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) Ribosomal_S15 PF00312.22 OWF42997.1 - 3.2e-11 43.3 1.8 1e-10 41.7 1.8 1.9 1 0 0 1 1 1 1 Ribosomal protein S15 ParcG PF10274.9 OWF42998.1 - 2.2e-82 275.6 0.0 2.7e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 OWF42998.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Peptidase_C1 PF00112.23 OWF42999.1 - 2.8e-71 240.1 2.4 4.6e-71 239.4 2.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF42999.1 - 5.6e-11 42.7 6.9 1e-10 41.9 6.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) T-box PF00907.22 OWF43000.1 - 4.2e-66 222.7 0.4 5.7e-66 222.3 0.4 1.2 1 0 0 1 1 1 1 T-box Glyco_hydro_36C PF16874.5 OWF43000.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain Paramecium_SA PF01508.16 OWF43001.1 - 0.7 10.4 8.2 13 6.3 1.6 2.6 1 1 2 3 3 3 0 Paramecium surface antigen domain HTH_45 PF14947.6 OWF43002.1 - 0.059 13.4 15.8 2 8.4 0.6 4.7 1 1 4 5 5 5 0 Winged helix-turn-helix RNR_N PF08343.10 OWF43002.1 - 0.14 12.2 5.3 11 6.2 0.4 3.3 1 1 3 4 4 4 0 Ribonucleotide reductase N-terminal DUF2279 PF10043.9 OWF43002.1 - 0.15 12.8 11.9 6.1 7.7 0.6 4.0 1 1 3 4 4 4 0 Predicted periplasmic lipoprotein (DUF2279) UPF0060 PF02694.15 OWF43002.1 - 0.25 11.6 10.0 2 8.7 2.2 2.4 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF5588 PF17826.1 OWF43002.1 - 5.1 5.9 9.5 4.6 6.0 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5588) UCH PF00443.29 OWF43003.1 - 5.6e-48 163.7 0.0 1.1e-47 162.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OWF43003.1 - 6.4e-17 61.6 8.2 6.4e-17 61.6 8.2 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein R3H PF01424.22 OWF43005.1 - 3.3e-11 43.0 0.1 1e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 R3H domain SUZ PF12752.7 OWF43005.1 - 4.2e-05 24.2 0.1 4.2e-05 24.2 0.1 4.2 4 0 0 4 4 4 1 SUZ domain Bac_chlorC PF02043.17 OWF43005.1 - 0.011 15.7 0.2 0.05 13.6 0.2 2.1 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein COPI_C PF06957.11 OWF43006.1 - 3.1e-184 612.4 0.0 4.4e-184 611.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 OWF43006.1 - 3e-142 474.8 0.0 4.3e-142 474.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 OWF43006.1 - 1.3e-35 120.7 17.9 1.3e-06 29.0 0.2 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF43006.1 - 9.3e-08 32.3 0.5 0.00047 20.4 0.1 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF43006.1 - 1.3 7.6 7.1 0.72 8.4 0.5 3.1 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Ig_3 PF13927.6 OWF43007.1 - 8.3e-65 215.4 4.0 3.1e-11 43.7 0.1 7.4 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 OWF43007.1 - 3.8e-54 180.7 0.0 3.3e-11 43.1 0.0 7.2 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF43007.1 - 8.2e-48 160.7 3.3 2.2e-09 37.5 0.1 7.2 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.25 OWF43007.1 - 1.7e-38 130.6 2.7 3.2e-06 27.2 0.0 6.7 6 0 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 OWF43007.1 - 1.9e-30 105.0 12.9 1.5e-08 34.8 0.0 4.9 5 0 0 5 5 4 4 Fibronectin type III domain V-set PF07686.17 OWF43007.1 - 6.3e-21 74.6 8.6 0.00021 21.4 0.1 7.9 6 3 1 7 7 7 5 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF43007.1 - 3.9e-09 35.9 0.8 0.071 12.7 0.0 5.7 6 0 0 6 6 6 2 Immunoglobulin domain Ig_4 PF16680.5 OWF43007.1 - 4.9e-08 33.1 0.6 0.042 14.1 0.0 5.1 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 OWF43007.1 - 5.8e-06 26.3 2.9 4.4 7.4 0.0 6.1 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 OWF43007.1 - 8.4e-06 25.8 0.7 0.93 9.6 0.0 4.2 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 OWF43007.1 - 0.00015 21.8 0.1 0.51 10.4 0.0 5.0 6 0 0 6 6 6 1 C17orf99 Ig domain V-set_CD47 PF08204.11 OWF43007.1 - 0.0022 17.9 1.7 4.7 7.2 0.0 4.6 5 0 0 5 5 5 1 CD47 immunoglobulin-like domain Interfer-bind PF09294.10 OWF43007.1 - 0.0026 18.1 0.2 18 5.7 0.0 4.3 5 0 0 5 5 5 0 Interferon-alpha/beta receptor, fibronectin type III Receptor_2B4 PF11465.8 OWF43007.1 - 0.014 15.6 0.0 5.6 7.2 0.0 4.0 3 1 1 4 4 4 0 Natural killer cell receptor 2B4 DUF5640 PF18692.1 OWF43007.1 - 0.16 12.0 0.7 15 5.7 0.0 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5640) Linker_histone PF00538.19 OWF43008.1 - 1.9e-26 92.2 3.1 1.9e-26 92.2 3.1 2.4 2 1 0 2 2 2 1 linker histone H1 and H5 family PHD PF00628.29 OWF43009.1 - 3.5e-44 148.5 104.8 1.7e-09 37.4 10.7 7.8 5 2 2 7 7 7 6 PHD-finger zf-HC5HC2H PF13771.6 OWF43009.1 - 3.3e-09 36.9 9.8 3.3e-09 36.9 9.8 7.7 4 2 3 7 7 7 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OWF43009.1 - 2.1e-06 27.8 8.3 2.1e-06 27.8 8.3 7.4 3 2 4 7 7 7 1 PHD-zinc-finger like domain HMG_box PF00505.19 OWF43009.1 - 6.3e-06 26.5 0.4 2e-05 24.9 0.4 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF43009.1 - 0.0025 18.4 0.2 0.01 16.4 0.2 2.1 1 0 0 1 1 1 1 HMG-box domain COG6 PF06419.11 OWF43009.1 - 5.5 5.1 8.6 8.9 4.4 8.6 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 FYRC PF05965.14 OWF43010.1 - 6.8e-24 83.8 0.0 2.3e-23 82.1 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 OWF43010.1 - 6.2e-19 67.6 4.1 1.2e-18 66.7 4.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 OWF43010.1 - 2.2e-16 60.7 2.9 3.8e-16 59.9 0.2 2.5 2 0 0 2 2 2 1 SET domain zf-HC5HC2H PF13771.6 OWF43010.1 - 7.3e-12 45.4 4.6 2.2e-11 43.8 4.6 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OWF43010.1 - 3.5e-11 43.2 4.5 9.8e-11 41.8 4.5 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain DUF4604 PF15377.6 OWF43010.1 - 0.39 11.1 11.5 0.72 10.3 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Rtf2 PF04641.12 OWF43010.1 - 1.7 8.0 8.5 3.6 6.9 8.5 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 OWF43010.1 - 9.9 4.8 5.4 17 4.0 5.4 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OWF43010.1 - 9.9 5.9 8.8 23 4.7 8.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 OWF43011.1 - 0 1136.4 0.2 0 1136.2 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family KASH_CCD PF14662.6 OWF43011.1 - 0.037 13.8 0.8 0.082 12.7 0.4 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Occludin_ELL PF07303.13 OWF43011.1 - 0.28 11.9 1.8 33 5.3 0.4 2.9 3 0 0 3 3 3 0 Occludin homology domain Galactosyl_T PF01762.21 OWF43012.1 - 1.6e-50 171.7 0.1 2.2e-50 171.2 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF43012.1 - 0.019 14.4 0.1 0.035 13.5 0.1 1.5 1 0 0 1 1 1 0 Fringe-like Smg8_Smg9 PF10220.9 OWF43012.1 - 0.11 10.8 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 RICTOR_V PF14668.6 OWF43013.1 - 0.03 14.6 0.9 15 5.9 0.1 3.6 1 1 3 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 bPH_4 PF06713.11 OWF43013.1 - 0.032 14.3 1.0 0.032 14.3 1.0 3.4 3 1 0 3 3 3 0 Bacterial PH domain Cucumopine_C PF18631.1 OWF43013.1 - 0.091 12.7 0.0 16 5.4 0.0 2.9 1 1 2 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain DUF5634 PF18681.1 OWF43013.1 - 0.1 12.9 12.5 35 4.8 0.3 5.9 1 1 4 6 6 6 0 Family of unknown function (DUF5634) zf-CCHC_3 PF13917.6 OWF43013.1 - 0.18 11.8 3.9 1.1e+02 2.9 0.1 5.2 7 0 0 7 7 7 0 Zinc knuckle PepSY_like PF11396.8 OWF43013.1 - 0.71 10.5 2.8 14 6.3 0.2 2.6 1 1 2 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like Galactosyl_T PF01762.21 OWF43014.1 - 2.3e-50 171.1 0.2 3.6e-50 170.5 0.2 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF43014.1 - 0.031 13.7 0.2 0.051 13.0 0.1 1.5 2 0 0 2 2 2 0 Fringe-like FbpC_C_terminal PF17845.1 OWF43015.1 - 6.2e-16 58.3 1.1 32 4.7 0.0 17.8 8 7 20 28 28 28 2 FbpC C-terminal regulatory nucleotide binding domain DUF4497 PF14924.6 OWF43015.1 - 1.2e-05 25.7 19.1 21 5.6 0.1 11.3 2 2 5 9 9 9 4 Protein of unknown function (DUF4497) Zn-C2H2_12 PF18112.1 OWF43016.1 - 1.6e-12 47.6 7.4 8.2e-09 35.8 1.7 2.7 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain Yuri_gagarin PF15934.5 OWF43016.1 - 0.022 14.6 12.8 0.79 9.5 0.1 3.1 2 1 0 2 2 2 0 Yuri gagarin zf-C2H2_4 PF13894.6 OWF43016.1 - 0.056 14.3 4.3 6.6 7.9 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger GAGA PF09237.11 OWF43016.1 - 0.087 12.6 0.3 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 GAGA factor UBZ_FAAP20 PF15750.5 OWF43016.1 - 0.089 12.7 0.9 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Mlp PF03304.13 OWF43016.1 - 0.18 12.0 6.9 0.072 13.3 3.3 2.0 2 0 0 2 2 2 0 Mlp lipoprotein family zf-H2C2_2 PF13465.6 OWF43016.1 - 0.29 11.6 4.0 4.6 7.8 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain PHM7_cyt PF14703.6 OWF43016.1 - 0.31 11.3 4.9 0.79 9.9 4.9 1.7 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Prok-RING_4 PF14447.6 OWF43016.1 - 0.36 10.7 1.3 4.4 7.2 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 OWF43016.1 - 0.37 10.7 9.4 1.3 8.9 0.0 4.1 4 1 1 5 5 5 0 Rad50 zinc hook motif CLZ PF16526.5 OWF43016.1 - 4.4 7.7 14.5 0.096 13.1 5.7 2.7 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ANTAR PF03861.14 OWF43017.1 - 5.1e-07 29.4 2.4 76 3.3 0.0 9.6 9 0 0 9 9 9 0 ANTAR domain CSTF2_hinge PF14327.6 OWF43017.1 - 6.5e-06 26.5 21.3 2.9 8.4 0.1 8.1 4 2 3 8 8 8 4 Hinge domain of cleavage stimulation factor subunit 2 TAD2 PF18521.1 OWF43017.1 - 2e-05 24.3 21.0 40 4.4 0.0 13.0 9 3 5 15 15 15 0 Transactivation domain 2 Coprogen_oxidas PF01218.18 OWF43017.1 - 0.0081 14.9 0.2 19 3.9 0.0 4.8 4 1 2 7 7 7 1 Coproporphyrinogen III oxidase RHSP PF07999.11 OWF43017.1 - 0.64 8.8 2.1 52 2.5 0.0 3.6 1 1 3 5 5 5 0 Retrotransposon hot spot protein Rhodopsin_N PF10413.9 OWF43019.1 - 9.1e-06 25.4 0.9 25 4.8 0.0 6.9 8 0 0 8 8 8 0 Amino terminal of the G-protein receptor rhodopsin FAO_M PF16350.5 OWF43019.1 - 0.00029 21.1 1.6 23 5.4 0.0 5.1 2 1 3 6 6 6 0 FAD dependent oxidoreductase central domain Csa1 PF06023.12 OWF43019.1 - 0.0019 17.6 6.1 9.8 5.4 0.0 4.9 1 1 6 7 7 7 2 CRISPR-associated exonuclease Csa1 TolA PF06519.11 OWF43019.1 - 0.0026 17.9 0.0 51 4.2 0.0 4.4 2 1 2 5 5 5 0 TolA C-terminal PLAC8 PF04749.17 OWF43019.1 - 0.0094 16.9 5.5 16 6.6 3.9 4.0 1 1 1 2 2 2 1 PLAC8 family Creatininase PF02633.14 OWF43019.1 - 0.014 14.9 0.1 9.8 5.6 0.0 3.3 5 0 0 5 5 5 0 Creatinine amidohydrolase DUF1610 PF07754.11 OWF43019.1 - 0.023 14.7 0.9 2.5e+02 1.7 0.0 5.7 8 0 0 8 8 8 0 Domain of unknown function (DUF1610) CRT-like PF08627.10 OWF43019.1 - 0.038 12.9 4.1 4.8 6.0 0.0 3.9 2 1 3 5 5 5 0 CRT-like, chloroquine-resistance transporter-like RPA_C PF08784.11 OWF43019.1 - 0.041 14.5 1.7 25 5.6 0.1 3.6 1 1 3 4 4 4 0 Replication protein A C terminal Osmo_CC PF08946.10 OWF43019.1 - 0.057 13.7 1.1 1.1e+02 3.1 0.0 5.2 7 0 0 7 7 7 0 Osmosensory transporter coiled coil DUF1088 PF06469.11 OWF43019.1 - 0.19 11.4 0.0 37 3.9 0.0 3.0 1 1 2 4 4 4 0 Domain of Unknown Function (DUF1088) STT3 PF02516.14 OWF43020.1 - 3.9e-145 484.5 44.7 2.5e-142 475.3 40.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 OWF43020.1 - 0.00084 19.6 17.1 0.00084 19.6 17.1 4.5 5 0 0 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase zinc_ribbon_10 PF10058.9 OWF43021.1 - 1.3e-19 69.6 1.6 2.3e-19 68.9 1.6 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein 7TMR-DISM_7TM PF07695.11 OWF43021.1 - 0.056 13.3 2.6 0.082 12.8 2.6 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling 2TM PF13239.6 OWF43021.1 - 0.085 13.2 2.1 0.14 12.5 2.1 1.3 1 0 0 1 1 1 0 2TM domain DUF4512 PF14975.6 OWF43021.1 - 1.5 9.7 4.0 2.2 9.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) zf-C2H2 PF00096.26 OWF43022.1 - 4.8e-28 96.0 69.4 0.00015 22.0 5.3 9.8 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43022.1 - 1.8e-25 88.2 52.7 3.2e-07 30.5 0.4 9.5 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF43022.1 - 7.5e-18 63.7 67.8 0.0042 17.8 0.5 9.8 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF43022.1 - 0.0024 17.6 0.5 0.0024 17.6 0.5 7.9 7 1 0 7 7 7 2 C2H2-type zinc-finger domain DUF2180 PF09947.9 OWF43022.1 - 0.0027 17.6 1.8 0.0027 17.6 1.8 3.1 3 2 1 4 4 4 1 Uncharacterized protein conserved in archaea (DUF2180) RYDR_ITPR PF01365.21 OWF43022.1 - 0.018 14.5 2.3 0.035 13.5 2.1 1.6 1 1 0 1 1 1 0 RIH domain zf_C2H2_ZHX PF18387.1 OWF43022.1 - 0.027 14.1 0.3 0.027 14.1 0.3 6.8 4 2 3 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain BolA PF01722.18 OWF43022.1 - 0.067 13.5 5.6 13 6.1 0.0 4.0 3 2 1 4 4 4 0 BolA-like protein Y_Y_Y PF07495.13 OWF43022.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Y_Y_Y domain zf-met PF12874.7 OWF43022.1 - 8.3 7.0 59.8 3.3 8.2 0.9 8.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type bZIP_2 PF07716.15 OWF43023.1 - 0.00023 21.2 3.9 0.00023 21.2 3.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF43023.1 - 0.001 19.1 4.3 0.0036 17.4 4.3 2.0 1 1 0 1 1 1 1 bZIP transcription factor DUF2870 PF11069.8 OWF43023.1 - 0.042 14.2 0.9 0.087 13.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Nefa_Nip30_N PF10187.9 OWF43023.1 - 0.045 14.1 1.8 0.1 13.0 1.8 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 TSC22 PF01166.18 OWF43023.1 - 0.076 13.3 1.0 0.56 10.5 0.3 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 OWF43023.1 - 0.28 11.6 6.8 0.091 13.2 3.3 2.1 2 1 0 2 2 2 0 Cell division protein ZapB DUF2570 PF10828.8 OWF43023.1 - 0.75 9.6 5.8 1.7 8.5 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SLED PF12140.8 OWF43023.1 - 1.1 9.8 4.2 2.3 8.7 0.7 2.3 2 0 0 2 2 2 0 SLED domain zf-C2H2_aberr PF17017.5 OWF43023.1 - 1.2 9.2 8.9 0.15 12.2 3.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger UQ_con PF00179.26 OWF43024.1 - 4.1e-30 104.3 0.0 5.7e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OWF43024.1 - 6.3e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 OWF43024.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B NAD_Gly3P_dh_N PF01210.23 OWF43025.1 - 1.4e-51 174.5 0.3 2.7e-51 173.6 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OWF43025.1 - 1.6e-46 158.1 1.3 1.8e-46 157.9 0.2 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 OWF43025.1 - 0.0004 20.9 0.1 1.4 9.6 0.0 2.7 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OWF43025.1 - 0.014 15.0 0.1 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TAP42 PF04177.12 OWF43026.1 - 1.6e-78 264.1 8.7 1.8e-78 263.9 8.7 1.0 1 0 0 1 1 1 1 TAP42-like family Complex1_LYR_2 PF13233.6 OWF43027.1 - 0.0028 18.4 0.2 0.0039 17.9 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Octopine_DH PF02317.17 OWF43027.1 - 0.03 14.4 0.1 1.5 8.9 0.1 1.9 1 1 1 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Ocnus PF05005.15 OWF43027.1 - 0.061 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) NAD_Gly3P_dh_N PF01210.23 OWF43029.1 - 3.9e-50 169.9 0.2 7.4e-50 169.0 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OWF43029.1 - 8.2e-45 152.6 0.1 1.9e-44 151.4 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 OWF43029.1 - 0.0016 19.0 0.3 2 9.0 0.0 2.7 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OWF43029.1 - 0.082 12.5 0.8 3 7.4 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GerD PF17898.1 OWF43029.1 - 0.14 12.1 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain SKICH PF17751.1 OWF43030.1 - 3.2e-31 107.9 0.6 3.2e-31 107.9 0.6 3.1 3 0 0 3 3 3 1 SKICH domain Zn-C2H2_12 PF18112.1 OWF43030.1 - 2.5e-12 47.0 7.7 6e-09 36.2 0.1 3.5 3 0 0 3 3 3 2 Autophagy receptor zinc finger-C2H2 domain ERM PF00769.19 OWF43030.1 - 4.3e-06 26.7 90.7 0.0022 17.9 11.5 4.1 2 1 1 3 3 3 3 Ezrin/radixin/moesin family KASH_CCD PF14662.6 OWF43030.1 - 4.3e-05 23.4 39.0 0.00072 19.4 17.5 5.5 1 1 4 5 5 4 2 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 OWF43030.1 - 9.1e-05 21.3 18.0 9.1e-05 21.3 18.0 4.2 2 1 2 4 4 3 1 AAA domain CALCOCO1 PF07888.11 OWF43030.1 - 0.00079 18.4 45.4 0.00079 18.4 45.4 4.0 1 1 2 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 OWF43030.1 - 0.0034 16.3 18.3 0.0034 16.3 18.3 5.1 2 1 3 5 5 5 2 Spc7 kinetochore protein Filament PF00038.21 OWF43030.1 - 0.0035 17.0 41.3 0.0035 17.0 41.3 4.3 1 1 3 4 4 3 1 Intermediate filament protein BST2 PF16716.5 OWF43030.1 - 0.013 16.0 7.6 0.013 16.0 7.6 7.8 3 3 6 9 9 9 0 Bone marrow stromal antigen 2 BRE1 PF08647.11 OWF43030.1 - 0.014 15.5 10.5 0.014 15.5 10.5 7.4 2 2 5 7 7 5 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 OWF43030.1 - 0.015 15.9 7.4 0.015 15.9 7.4 6.9 3 2 3 6 6 6 0 Initiation control protein YabA zf-C2H2_4 PF13894.6 OWF43030.1 - 0.04 14.8 4.1 6.9 7.8 0.0 3.5 3 0 0 3 3 2 0 C2H2-type zinc finger MscS_porin PF12795.7 OWF43030.1 - 0.08 12.5 52.7 0.039 13.5 18.6 4.4 2 1 3 5 5 5 0 Mechanosensitive ion channel porin domain PKcGMP_CC PF16808.5 OWF43030.1 - 0.14 12.0 0.1 0.14 12.0 0.1 5.2 5 0 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IL23 PF16649.5 OWF43030.1 - 0.16 12.0 1.4 3.2 7.8 0.2 2.5 2 0 0 2 2 2 0 Interleukin 23 subunit alpha LPP PF04728.13 OWF43030.1 - 0.45 11.0 10.5 12 6.3 0.5 5.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper zf-Di19 PF05605.12 OWF43030.1 - 1 9.7 9.8 0.18 12.1 2.9 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Laminin_II PF06009.12 OWF43030.1 - 2.4 8.2 54.2 0.071 13.1 6.6 5.5 3 1 1 5 5 5 0 Laminin Domain II THAP PF05485.12 OWF43031.1 - 2.1e-10 41.4 1.0 2.2e-10 41.3 1.0 1.0 1 0 0 1 1 1 1 THAP domain Cu_bind_like PF02298.17 OWF43032.1 - 0.005 16.8 2.0 1.4 8.9 0.1 3.3 2 1 1 3 3 3 3 Plastocyanin-like domain DUF3739 PF12545.8 OWF43033.1 - 0.032 14.7 23.7 0.48 10.9 3.6 2.7 1 1 1 2 2 2 0 Filamentous haemagglutinin family outer membrane protein Ribosomal_L26 PF16906.5 OWF43033.1 - 0.45 11.0 14.8 5.3e+02 1.2 0.0 5.9 1 1 1 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal DUF1983 PF09327.11 OWF43033.1 - 0.6 10.2 44.2 29 4.8 4.4 6.9 1 1 3 4 4 4 0 Domain of unknown function (DUF1983) P30 PF07390.11 OWF43033.1 - 0.7 10.0 10.8 4.9 7.2 0.6 2.6 1 1 1 2 2 2 0 Mycoplasma P30 protein DUF3540 PF12059.8 OWF43033.1 - 6.4 6.6 35.1 8.2 6.2 25.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) PX PF00787.24 OWF43034.1 - 6.2e-22 77.7 0.1 1e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 PX domain Ank_2 PF12796.7 OWF43035.1 - 9.4e-41 138.3 6.8 1.1e-11 45.1 1.3 5.6 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF43035.1 - 4.3e-33 113.2 12.4 5.5e-08 33.2 0.2 8.0 5 3 2 8 8 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF43035.1 - 7.7e-24 83.5 7.3 3.3e-07 30.5 0.0 8.2 3 3 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF43035.1 - 2.5e-20 70.4 11.8 0.0031 17.9 0.0 10.6 11 0 0 11 11 10 4 Ankyrin repeat Ank PF00023.30 OWF43035.1 - 2.7e-15 56.0 19.1 0.0041 17.5 0.0 9.5 10 1 1 11 11 9 3 Ankyrin repeat TPR_11 PF13414.6 OWF43035.1 - 0.0001 21.9 6.6 1.3 8.8 0.2 4.5 3 1 1 4 4 4 1 TPR repeat zf-RING_2 PF13639.6 OWF43035.1 - 0.00051 20.3 9.0 0.00051 20.3 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain AAA_16 PF13191.6 OWF43035.1 - 0.00069 20.0 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 OWF43035.1 - 0.0022 18.6 3.3 3.2 8.5 0.7 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 OWF43035.1 - 0.0041 17.1 8.3 0.0041 17.1 8.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF43035.1 - 0.0043 17.0 8.5 0.0058 16.6 6.5 2.5 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF43035.1 - 0.013 15.4 8.3 0.05 13.5 8.3 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF43035.1 - 0.019 14.8 11.8 0.026 14.3 9.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 OWF43035.1 - 0.02 15.0 0.6 0.072 13.2 0.6 1.9 1 0 0 1 1 1 0 FYVE zinc finger AAA_28 PF13521.6 OWF43035.1 - 0.023 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 OWF43035.1 - 0.026 14.7 4.2 7.1 7.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat cobW PF02492.19 OWF43035.1 - 0.035 13.7 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TPR_2 PF07719.17 OWF43035.1 - 0.037 14.1 11.7 7.1 7.0 2.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 OWF43035.1 - 0.048 13.5 7.7 1.1 9.2 8.4 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TPR_19 PF14559.6 OWF43035.1 - 0.05 14.1 5.3 0.091 13.3 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat YHS PF04945.13 OWF43035.1 - 0.064 13.4 0.2 0.58 10.3 0.2 2.5 2 0 0 2 2 2 0 YHS domain AAA_29 PF13555.6 OWF43035.1 - 0.079 12.7 0.1 0.31 10.8 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 OWF43035.1 - 0.085 12.8 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 OWF43035.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OWF43035.1 - 0.14 12.7 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_9 PF13371.6 OWF43035.1 - 0.15 12.2 1.6 0.63 10.2 1.6 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF43035.1 - 0.35 11.8 5.2 1.2 10.1 2.3 3.3 2 1 1 3 3 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 OWF43035.1 - 0.81 10.0 6.7 2.7 8.4 6.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain IBR PF01485.21 OWF43035.1 - 4.2 7.7 7.9 0.87 9.9 3.4 2.2 2 0 0 2 2 1 0 IBR domain, a half RING-finger domain TPR_1 PF00515.28 OWF43035.1 - 7.5 6.6 12.6 9.4 6.2 1.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Tubulin-binding PF00418.19 OWF43038.1 - 3.7e-48 161.2 44.1 1.3e-14 53.9 1.0 7.4 7 0 0 7 7 7 5 Tau and MAP protein, tubulin-binding repeat DUF4573 PF15140.6 OWF43038.1 - 3.4e-17 62.8 42.6 2.2e-08 34.1 7.4 5.4 4 1 3 7 7 7 4 Domain of unknown function (DUF4573) Tcp10_C PF07202.13 OWF43038.1 - 1.3e-09 38.3 6.0 0.00055 19.9 0.3 4.0 1 1 2 3 3 3 3 T-complex protein 10 C-terminus AMOP PF03782.17 OWF43039.1 - 3.5e-27 95.3 5.6 8.1e-27 94.1 5.6 1.6 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 OWF43039.1 - 1.2e-21 77.4 0.7 3.7e-21 75.9 0.7 1.9 1 0 0 1 1 1 1 Nidogen-like VWD PF00094.25 OWF43039.1 - 8.4e-17 61.9 0.8 2.5e-16 60.3 0.8 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain Sushi PF00084.20 OWF43039.1 - 7.8e-08 32.8 0.7 2.1e-07 31.4 0.4 2.0 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) TMEM154 PF15102.6 OWF43039.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4251 PF14059.6 OWF43039.1 - 0.082 12.9 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) PIF1 PF05970.14 OWF43041.1 - 0.0019 17.5 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 OWF43041.1 - 0.037 13.9 0.2 0.098 12.5 0.2 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PHD PF00628.29 OWF43042.1 - 5.3e-07 29.4 15.5 9.4e-07 28.6 14.3 2.1 2 1 1 3 3 3 2 PHD-finger WAC_Acf1_DNA_bd PF10537.9 OWF43043.1 - 1.7e-31 108.7 0.1 1.7e-31 108.7 0.1 3.0 3 0 0 3 3 1 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 OWF43043.1 - 4.7e-22 77.6 24.2 2.7e-12 46.4 7.1 2.7 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 OWF43043.1 - 2.3e-19 69.3 5.1 2.3e-19 69.2 0.1 3.1 3 0 0 3 3 3 1 Bromodomain WSD PF15613.6 OWF43043.1 - 5.7e-19 68.4 0.9 5.7e-19 68.4 0.9 7.0 5 3 0 5 5 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OWF43043.1 - 1.5e-10 41.2 2.1 2.5e-10 40.5 0.3 2.4 3 0 0 3 3 2 1 DDT domain WHIM1 PF15612.6 OWF43043.1 - 1.1e-05 24.9 0.2 2.8e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 zf-HC5HC2H PF13771.6 OWF43043.1 - 1.6e-05 25.1 11.9 0.0054 17.0 5.8 3.1 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.6 OWF43043.1 - 0.00021 20.8 14.1 0.0019 17.7 4.1 2.8 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H_2 PF13832.6 OWF43043.1 - 0.062 13.5 11.2 0.11 12.7 3.9 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_2 PF03107.16 OWF43043.1 - 0.18 12.1 14.2 0.39 11.1 1.6 2.7 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 OWF43043.1 - 3.8 7.5 15.3 5.5 7.0 3.4 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Cu_amine_oxidN1 PF07833.11 OWF43044.1 - 1e-05 25.9 1.3 1.9 9.1 0.0 4.0 1 1 2 3 3 3 2 Copper amine oxidase N-terminal domain FokI_C PF02980.16 OWF43044.1 - 0.001 19.1 5.2 2 8.5 0.0 4.3 2 2 2 4 4 4 2 Restriction endonuclease FokI, catalytic domain TAA-Trp-ring PF15401.6 OWF43044.1 - 0.0014 19.1 4.5 89 3.7 0.0 6.9 4 4 1 6 6 6 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin NACHT_sigma PF17106.5 OWF43044.1 - 0.0021 18.1 2.2 2.6 8.2 0.1 4.4 5 0 0 5 5 5 1 Sigma domain on NACHT-NTPases Cys_rich_VLP PF14194.6 OWF43044.1 - 0.03 14.4 7.9 15 5.8 0.0 4.8 5 0 0 5 5 5 0 Cysteine-rich VLP DUF5335 PF17269.2 OWF43044.1 - 0.051 13.4 1.9 22 4.9 0.2 3.8 1 1 2 4 4 4 0 Family of unknown function (DUF5335) LLGL PF08366.13 OWF43044.1 - 0.2 12.0 14.0 6.5 7.2 0.7 4.6 1 1 3 4 4 4 0 LLGL2 FtsA PF14450.6 OWF43044.1 - 1.9 8.9 18.2 58 4.2 2.4 5.4 2 2 0 2 2 2 0 Cell division protein FtsA Neur_chan_memb PF02932.16 OWF43045.1 - 2.7e-13 50.5 0.4 3e-13 50.4 0.4 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Glyco_trans_1_4 PF13692.6 OWF43045.1 - 0.039 14.4 0.1 0.044 14.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 OrfB_IS605 PF01385.19 OWF43045.1 - 0.069 13.4 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Probable transposase BRI3BP PF14965.6 OWF43045.1 - 0.086 12.3 0.1 0.26 10.8 0.1 1.7 1 1 0 1 1 1 0 Negative regulator of p53/TP53 Choline_kinase PF01633.20 OWF43046.1 - 2.5e-43 148.2 0.0 3.9e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OWF43046.1 - 0.00067 19.7 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 OWF43047.1 - 2.4e-39 135.2 52.7 9.4e-37 126.7 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 OWF43047.1 - 0.03 14.6 2.9 0.77 10.1 0.1 3.2 2 0 0 2 2 2 0 Transglycosylase associated protein MFS_3 PF05977.13 OWF43047.1 - 1.1 7.5 10.0 0.093 11.1 4.3 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector CrgA PF06781.12 OWF43047.1 - 4.8 7.3 6.1 5.3 7.2 1.7 2.9 3 0 0 3 3 3 0 Cell division protein CrgA Galactosyl_T PF01762.21 OWF43052.1 - 2.2e-41 141.8 0.2 2.8e-41 141.5 0.2 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF43052.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 OWF43053.1 - 4.9e-14 52.6 0.3 6.7e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 Galactosyltransferase Abhydrolase_2 PF02230.16 OWF43055.1 - 1.2e-60 205.0 0.3 1.4e-60 204.8 0.3 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OWF43055.1 - 1.1e-06 28.1 0.0 0.00045 19.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 OWF43055.1 - 2.7e-05 23.8 0.0 3.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OWF43055.1 - 7e-05 22.8 0.0 0.015 15.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF43055.1 - 7.1e-05 23.5 0.0 0.00014 22.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OWF43055.1 - 0.0002 20.9 0.3 0.32 10.4 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OWF43055.1 - 0.00061 19.5 1.7 0.04 13.5 0.1 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold DUF2974 PF11187.8 OWF43055.1 - 0.0018 17.8 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.20 OWF43055.1 - 0.002 17.8 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.13 OWF43055.1 - 0.012 15.3 0.1 0.04 13.6 0.1 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Cutinase PF01083.22 OWF43055.1 - 0.028 14.4 0.0 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 Cutinase Lipase_3 PF01764.25 OWF43055.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) POP1 PF06978.11 OWF43056.1 - 8.2e-34 117.4 34.2 8.3e-23 81.5 7.0 3.6 3 1 1 4 4 4 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OWF43056.1 - 3.1e-28 98.0 0.1 3.1e-28 98.0 0.1 3.4 5 0 0 5 5 5 1 POPLD (NUC188) domain GCV_T PF01571.21 OWF43056.1 - 9.5e-07 28.4 0.3 0.002 17.6 0.0 2.9 4 0 0 4 4 4 2 Aminomethyltransferase folate-binding domain Fimbrial_CS1 PF04449.12 OWF43056.1 - 0.031 14.4 0.6 0.064 13.4 0.6 1.5 1 0 0 1 1 1 0 CS1 type fimbrial major subunit Ribonuc_L-PSP PF01042.21 OWF43057.1 - 3.8e-40 136.6 0.9 4.4e-40 136.5 0.9 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Corona_6B_7B PF03262.13 OWF43057.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Coronavirus 6B/7B protein FAD_binding_6 PF00970.24 OWF43058.1 - 1.9e-24 85.9 0.0 2.8e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OWF43058.1 - 9.6e-12 45.5 0.0 3.9e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.9 OWF43058.1 - 4.8e-09 35.7 5.2 4.8e-09 35.7 5.2 4.5 6 1 0 6 6 6 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.12 OWF43058.1 - 0.0062 16.7 0.0 0.017 15.3 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain zf-C2H2 PF00096.26 OWF43059.1 - 5.2e-16 58.1 45.8 0.0014 19.0 1.0 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43059.1 - 1.3e-13 50.5 42.2 0.00083 20.0 2.4 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43059.1 - 1e-07 32.0 43.0 0.099 13.1 0.4 7.3 7 1 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF43059.1 - 1e-05 25.4 42.1 0.0018 18.3 1.4 7.5 7 1 0 7 7 7 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF43059.1 - 6.4e-05 22.6 33.3 0.076 12.8 6.4 5.8 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-met PF12874.7 OWF43059.1 - 0.00039 20.7 38.1 0.19 12.1 0.9 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OWF43059.1 - 0.0018 18.0 0.6 0.0018 18.0 0.6 5.3 6 0 0 6 6 5 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OWF43059.1 - 0.011 16.1 35.1 0.45 10.9 2.1 6.0 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.6 OWF43059.1 - 0.012 15.5 18.4 1 9.3 0.1 5.7 6 0 0 6 6 6 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 OWF43059.1 - 0.028 14.3 13.7 0.091 12.7 1.8 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type L_protein_N PF15518.6 OWF43059.1 - 0.042 13.7 0.5 1.4 8.8 0.1 2.4 1 1 1 2 2 2 0 L protein N-terminus zf_UBZ PF18439.1 OWF43059.1 - 0.16 11.6 23.6 4 7.1 0.2 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 OWF43059.1 - 0.17 11.8 6.4 0.4 10.6 0.2 3.5 3 1 0 3 3 3 0 C2H2 type zinc-finger (1 copy) PhnA_Zn_Ribbon PF08274.12 OWF43059.1 - 0.3 11.1 17.2 2.8 8.0 0.5 5.2 5 1 0 5 5 5 0 PhnA Zinc-Ribbon zf-BED PF02892.15 OWF43059.1 - 1 9.4 38.2 0.14 12.2 4.5 5.6 2 2 3 6 6 6 0 BED zinc finger ROS_MUCR PF05443.11 OWF43059.1 - 1.2 9.2 4.7 0.78 9.8 0.4 2.4 2 1 0 3 3 3 0 ROS/MUCR transcriptional regulator protein zinc_ribbon_15 PF17032.5 OWF43059.1 - 2.4 9.0 29.8 1.2e+02 3.6 15.1 4.0 1 1 2 3 3 3 0 zinc-ribbon family Trm112p PF03966.16 OWF43059.1 - 2.7 8.6 7.1 1.8 9.2 0.3 3.2 2 1 1 3 3 3 0 Trm112p-like protein tRNA-synt_2b PF00587.25 OWF43060.1 - 2.3e-33 115.6 0.0 3.6e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3797 PF12677.7 OWF43061.1 - 0.49 10.3 4.3 5.2 7.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DM PF00751.18 OWF43062.1 - 3.4e-22 78.1 12.5 7.3e-22 77.0 12.5 1.6 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 OWF43062.1 - 5.4e-08 32.3 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif UCR_14kD PF02271.16 OWF43062.1 - 0.15 12.0 3.4 0.3 11.1 3.1 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF4744 PF15918.5 OWF43063.1 - 0.013 16.3 29.8 3.8 8.4 4.9 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4744) Herpes_BLLF1 PF05109.13 OWF43063.1 - 4.9 5.0 29.6 22 2.8 29.6 1.8 1 1 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) BIR PF00653.21 OWF43066.1 - 1.3e-28 99.5 6.9 2.3e-19 69.8 0.5 3.9 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF43066.1 - 2.6e-10 40.0 10.9 2.6e-10 40.0 10.9 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF43066.1 - 0.0063 16.4 12.0 0.0063 16.4 12.0 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC PF07967.13 OWF43066.1 - 0.023 14.7 0.7 0.023 14.7 0.7 2.7 4 0 0 4 4 4 0 C3HC zinc finger-like zf-C3HC4 PF00097.25 OWF43067.1 - 5.9e-08 32.5 9.1 5.9e-08 32.5 9.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF43067.1 - 2.6e-07 30.5 7.6 2.6e-07 30.5 7.6 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF43067.1 - 1.3e-06 28.6 7.9 1.3e-06 28.6 7.9 3.7 4 0 0 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 OWF43067.1 - 2.2e-06 27.6 7.8 2.2e-06 27.6 7.8 3.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 OWF43067.1 - 5.7e-06 26.4 26.3 7.8e-06 26.0 8.7 3.7 3 1 0 3 3 2 2 B-box zinc finger zf-RING_11 PF17123.5 OWF43067.1 - 0.00045 19.9 4.2 0.00045 19.9 4.2 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF43067.1 - 0.0005 19.8 7.8 0.0005 19.8 7.8 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.28 OWF43067.1 - 0.0017 18.5 0.1 0.0045 17.1 0.1 1.7 1 0 0 1 1 1 1 SPRY domain Filamin PF00630.19 OWF43067.1 - 0.0039 18.0 0.1 0.022 15.6 0.0 2.3 2 0 0 2 2 2 1 Filamin/ABP280 repeat zf-RING_4 PF14570.6 OWF43067.1 - 0.004 16.9 8.0 0.004 16.9 8.0 3.5 3 0 0 3 3 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OWF43067.1 - 0.0042 16.9 7.3 0.0042 16.9 7.3 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 CEBP_ZZ PF16366.5 OWF43067.1 - 0.029 14.6 34.8 0.054 13.8 4.5 4.3 3 1 1 4 4 4 0 Cytoplasmic polyadenylation element-binding protein ZZ domain T6PP_N PF18572.1 OWF43067.1 - 0.16 11.8 2.9 8.1 6.3 0.8 2.8 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Arylesterase PF01731.20 OWF43068.1 - 7.2e-16 58.2 0.0 1.7e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 OWF43068.1 - 1.2e-08 34.9 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OWF43068.1 - 0.0017 18.4 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase CUE PF02845.16 OWF43069.1 - 0.019 14.6 0.4 0.14 11.9 0.4 2.4 1 1 0 1 1 1 0 CUE domain Mei4 PF13971.6 OWF43070.1 - 6.3e-06 25.9 18.1 1.6e-05 24.6 18.1 1.7 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 Mito_fiss_reg PF05308.11 OWF43070.1 - 0.0025 18.0 3.7 0.0025 18.0 3.7 1.9 1 1 1 2 2 2 1 Mitochondrial fission regulator GvpG PF05120.12 OWF43070.1 - 0.018 15.0 0.1 0.074 13.1 0.1 2.0 1 0 0 1 1 1 0 Gas vesicle protein G YlzJ PF14035.6 OWF43070.1 - 0.24 11.6 1.0 0.65 10.2 0.2 2.2 2 0 0 2 2 2 0 YlzJ-like protein RebB PF11747.8 OWF43070.1 - 3.6 7.7 5.4 1.1 9.4 0.4 2.7 3 0 0 3 3 3 0 Killing trait NAD_binding_2 PF03446.15 OWF43071.1 - 9.1e-24 84.4 0.1 1.3e-23 83.9 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OWF43071.1 - 9.5e-20 71.1 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase EMC1_C PF07774.13 OWF43072.1 - 2e-73 246.6 0.2 5.4e-73 245.2 0.1 1.8 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OWF43072.1 - 1.5e-13 50.9 1.0 2.2e-08 34.0 0.7 3.8 3 0 0 3 3 3 2 PQQ-like domain Fer2_4 PF13510.6 OWF43072.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DPPIV_N PF00930.21 OWF43072.1 - 0.082 11.7 0.1 5.4 5.7 0.0 2.9 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_3 PF13570.6 OWF43072.1 - 0.083 13.4 0.1 1.6 9.4 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain ATP-synt_D PF01813.17 OWF43073.1 - 9.6e-05 22.3 0.1 0.00079 19.3 0.1 2.0 1 1 0 1 1 1 1 ATP synthase subunit D WW_FCH_linker PF16623.5 OWF43073.1 - 0.052 14.3 0.5 0.1 13.3 0.4 1.6 1 1 0 1 1 1 0 Unstructured linker region between on GAS7 protein Kelch_4 PF13418.6 OWF43074.1 - 1.1e-29 102.2 11.0 8.8e-11 41.7 0.6 6.1 3 1 3 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF43074.1 - 1.6e-29 101.6 8.9 5.7e-10 39.2 0.3 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OWF43074.1 - 5.7e-22 77.0 8.8 1.3e-06 27.8 0.8 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 OWF43074.1 - 6.6e-21 73.9 10.5 1.2e-07 31.6 0.2 6.6 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 OWF43074.1 - 8.7e-20 70.3 12.5 3.6e-06 27.0 0.8 5.8 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OWF43074.1 - 1.2e-16 59.9 15.3 3.5e-05 23.6 0.1 6.5 6 0 0 6 6 6 4 Kelch motif F-box-like PF12937.7 OWF43074.1 - 4.5e-09 36.1 0.0 1.4e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 OWF43074.1 - 7e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 OWF43074.1 - 0.031 14.2 0.0 0.098 12.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain Apolipo_F PF15148.6 OWF43075.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein F MRP-S22 PF10245.9 OWF43077.1 - 7.4e-77 258.4 2.4 1e-76 257.9 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 DUF3337 PF11816.8 OWF43077.1 - 0.089 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) AAA_16 PF13191.6 OWF43078.1 - 2.1e-10 41.3 0.0 2.2e-09 37.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF4062 PF13271.6 OWF43078.1 - 2.3e-10 40.7 0.1 3.1e-09 37.1 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) NACHT PF05729.12 OWF43078.1 - 5.4e-08 32.9 0.1 1.1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 OWF43078.1 - 1.6e-05 25.0 0.0 6e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OWF43078.1 - 2.3e-05 24.7 0.0 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain PQQ_2 PF13360.6 OWF43078.1 - 9.8e-05 22.0 0.0 0.51 9.9 0.0 4.0 3 1 1 4 4 4 3 PQQ-like domain APAF1_C PF17908.1 OWF43078.1 - 0.0014 18.6 0.1 0.0066 16.5 0.1 2.2 1 0 0 1 1 1 1 APAF-1 helical domain AAA PF00004.29 OWF43078.1 - 0.002 18.5 0.0 0.0089 16.5 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OWF43078.1 - 0.0028 16.9 0.0 0.0092 15.2 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain Lactonase PF10282.9 OWF43078.1 - 0.0069 15.7 0.2 0.13 11.5 0.0 2.9 4 0 0 4 4 4 1 Lactonase, 7-bladed beta-propeller AAA_24 PF13479.6 OWF43078.1 - 0.087 12.5 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sybindin PF04099.12 OWF43079.1 - 2.2e-57 193.0 0.0 2.5e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OWF43079.1 - 5.9e-09 36.1 0.0 7.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PDZ_6 PF17820.1 OWF43079.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF43079.1 - 0.037 14.4 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF4615 PF15393.6 OWF43080.1 - 5.3e-34 117.8 11.3 1e-32 113.6 4.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4615) LRR_6 PF13516.6 OWF43081.1 - 2.9e-31 104.8 22.5 3.6e-05 23.5 0.0 9.7 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 OWF43081.1 - 2e-06 28.0 15.3 0.1 13.0 0.6 6.0 5 1 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF43081.1 - 6.8e-05 22.5 12.3 0.029 14.1 1.4 6.1 5 2 1 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 OWF43081.1 - 7.4e-05 22.8 0.9 1.2e+02 3.8 0.0 6.8 9 0 0 9 9 9 0 Leucine Rich Repeat FAM181 PF15238.6 OWF43082.1 - 0.00098 19.0 3.4 0.00098 19.0 3.4 2.2 1 1 1 2 2 2 1 FAM181 Trehalase_Ca-bi PF07492.11 OWF43083.1 - 0.012 15.3 14.3 1.3 8.9 0.2 5.2 5 1 1 6 6 6 0 Neutral trehalase Ca2+ binding domain Trehalase_Ca-bi PF07492.11 OWF43084.1 - 0.13 12.0 3.0 7 6.5 0.1 3.4 4 0 0 4 4 4 0 Neutral trehalase Ca2+ binding domain GYF PF02213.16 OWF43086.1 - 1.1e-19 69.8 0.4 3.2e-19 68.3 0.4 1.9 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OWF43086.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 2.6 3 0 0 3 3 3 1 GYF domain 2 Pkinase_Tyr PF07714.17 OWF43087.1 - 2.2e-84 282.8 0.1 5e-84 281.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OWF43087.1 - 2.5e-45 154.9 0.0 4.1e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UBA PF00627.31 OWF43087.1 - 0.00045 20.0 0.1 0.19 11.7 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain HBS1_N PF08938.10 OWF43087.1 - 0.005 17.1 0.4 5.2 7.4 0.3 3.1 1 1 1 2 2 2 2 HBS1 N-terminus PBD PF00786.28 OWF43087.1 - 0.01 16.2 0.6 0.039 14.3 0.1 2.3 2 0 0 2 2 2 0 P21-Rho-binding domain Haspin_kinase PF12330.8 OWF43087.1 - 0.017 14.1 0.0 0.042 12.8 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain TAP_C PF03943.13 OWF43087.1 - 0.025 14.2 0.4 9.4 6.0 0.0 2.7 2 0 0 2 2 2 0 TAP C-terminal domain UBA_4 PF14555.6 OWF43087.1 - 0.035 13.9 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain Kinase-like PF14531.6 OWF43087.1 - 0.22 10.8 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like GTP_EFTU_D3 PF03143.17 OWF43089.1 - 8.4e-29 100.1 0.0 4e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 OWF43089.1 - 6.6e-11 42.1 0.1 1.3e-08 34.6 0.2 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OWF43089.1 - 1.8e-08 34.6 0.7 1e-07 32.2 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 G-alpha PF00503.20 OWF43089.1 - 0.0016 17.7 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 OWF43089.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3410 PF11890.8 OWF43090.1 - 1 9.2 14.7 56 3.6 0.1 6.6 1 1 7 8 8 8 0 Domain of unknown function (DUF3410) NIDO PF06119.14 OWF43092.1 - 2.1e-19 70.3 0.6 5e-19 69.0 0.0 1.9 2 1 0 2 2 2 1 Nidogen-like LnmK_N_HDF PF18238.1 OWF43092.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain NIDO PF06119.14 OWF43093.1 - 3.4e-21 76.0 0.6 7.5e-21 74.9 0.2 1.8 2 0 0 2 2 2 1 Nidogen-like DUF5521 PF17659.1 OWF43093.1 - 0.0019 16.2 0.0 0.0023 15.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5521) DUF1460 PF07313.12 OWF43093.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Methyltransf_19 PF04672.12 OWF43093.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Amino_oxidase PF01593.24 OWF43093.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase TNFR_c6 PF00020.18 OWF43094.1 - 0.00034 21.0 24.2 0.0019 18.5 1.5 4.7 5 0 0 5 5 5 2 TNFR/NGFR cysteine-rich region SUa-2TM PF18179.1 OWF43094.1 - 0.018 14.4 0.7 0.026 13.8 0.7 1.1 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain TMEM154 PF15102.6 OWF43094.1 - 0.041 13.8 0.2 0.081 12.8 0.2 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF3964 PF13107.6 OWF43095.1 - 0.071 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) AhpC-TSA_2 PF13911.6 OWF43096.1 - 3.9e-20 72.1 0.0 7.3e-20 71.2 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Noggin PF05806.12 OWF43097.1 - 1.7e-06 28.1 4.1 2.1e-06 27.8 4.1 1.1 1 0 0 1 1 1 1 Noggin IL17 PF06083.11 OWF43097.1 - 0.01 16.3 2.1 0.026 15.0 2.1 1.7 1 0 0 1 1 1 0 Interleukin-17 Ribosomal_L38e PF01781.18 OWF43097.1 - 0.034 14.2 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L38e protein family InaF-motif PF15018.6 OWF43097.1 - 0.19 11.6 1.9 0.37 10.7 1.9 1.4 1 0 0 1 1 1 0 TRP-interacting helix AMP-binding PF00501.28 OWF43098.1 - 2.5e-52 177.9 0.0 3.1e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF43098.1 - 5.9e-07 30.4 0.0 1e-06 29.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UQ_con PF00179.26 OWF43099.1 - 4.6e-47 159.2 0.2 6.8e-47 158.6 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF43099.1 - 0.014 15.1 0.0 0.043 13.5 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 OWF43099.1 - 0.072 13.4 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 RWD domain DUF2457 PF10446.9 OWF43099.1 - 0.59 9.2 9.4 0.75 8.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Y_phosphatase PF00102.27 OWF43100.1 - 1.2e-78 264.0 0.0 2.9e-78 262.7 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 OWF43100.1 - 1.3e-30 106.2 0.0 2.3e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OWF43100.1 - 2.5e-12 47.1 0.0 5.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HBS1_N PF08938.10 OWF43100.1 - 0.0055 17.0 0.0 0.021 15.1 0.0 2.0 1 0 0 1 1 1 1 HBS1 N-terminus DSPc PF00782.20 OWF43100.1 - 0.012 15.4 0.1 0.055 13.3 0.0 2.2 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF43100.1 - 0.016 15.4 0.8 0.057 13.5 0.0 2.4 2 1 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF43100.1 - 0.019 14.9 0.2 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family CRAL_TRIO_N PF03765.15 OWF43100.1 - 0.17 12.1 1.5 0.43 10.8 0.6 2.2 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain RDV-p3 PF09231.10 OWF43100.1 - 0.19 9.4 0.0 0.32 8.7 0.0 1.2 1 0 0 1 1 1 0 Rice dwarf virus p3 F5_F8_type_C PF00754.25 OWF43101.1 - 1.4e-15 57.5 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PAN_1 PF00024.26 OWF43101.1 - 4.2e-05 23.4 4.3 0.0001 22.2 4.3 1.7 1 0 0 1 1 1 1 PAN domain Lectin_C PF00059.21 OWF43101.1 - 0.00083 20.1 0.0 0.0021 18.8 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain PAN_2 PF08276.11 OWF43101.1 - 0.0043 17.1 3.0 0.011 15.8 3.0 1.7 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 OWF43101.1 - 0.006 16.5 4.1 0.032 14.1 4.1 2.2 1 1 0 1 1 1 1 PAN domain CP_ATPgrasp_2 PF14403.6 OWF43101.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 MFS_1 PF07690.16 OWF43105.1 - 3e-45 154.7 37.6 8.3e-32 110.5 11.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3697 PF12478.8 OWF43106.1 - 4.8e-14 52.2 0.0 1.3e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 DUF1296 PF06972.11 OWF43106.1 - 0.049 13.8 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) PTPS PF01242.19 OWF43107.1 - 4.7e-10 39.5 0.1 1.2e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase S_100 PF01023.19 OWF43107.1 - 0.011 15.4 0.2 0.092 12.5 0.0 2.6 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain TrmO PF01980.16 OWF43109.1 - 7.6e-45 152.0 0.0 2.7e-44 150.2 0.0 1.9 2 0 0 2 2 2 1 tRNA-methyltransferase O TrmO_C PF18389.1 OWF43109.1 - 7.7e-06 25.9 0.0 0.00019 21.4 0.0 2.4 1 1 0 1 1 1 1 TrmO C-terminal domain WH1 PF00568.23 OWF43110.1 - 1.1e-32 112.3 0.2 2.1e-32 111.4 0.2 1.5 1 0 0 1 1 1 1 WH1 domain FPP PF05911.11 OWF43110.1 - 0.0015 16.9 14.3 0.0015 16.9 14.3 2.1 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil GAS PF13851.6 OWF43110.1 - 0.038 13.4 32.3 0.015 14.6 26.8 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4366 PF14283.6 OWF43110.1 - 0.038 14.0 1.7 0.079 13.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) BST2 PF16716.5 OWF43110.1 - 0.099 13.2 27.6 0.21 12.2 9.2 3.8 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 ERM PF00769.19 OWF43110.1 - 0.12 12.1 28.8 0.013 15.3 24.5 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Leu_zip PF15294.6 OWF43110.1 - 0.43 10.1 23.5 0.33 10.4 7.8 2.4 1 1 1 2 2 2 0 Leucine zipper Jnk-SapK_ap_N PF09744.9 OWF43110.1 - 0.46 10.7 35.1 0.4 10.9 13.3 2.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 OWF43110.1 - 0.47 10.7 32.6 0.036 14.3 23.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 OWF43110.1 - 0.49 8.9 10.2 0.34 9.4 8.4 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family HalX PF08663.10 OWF43110.1 - 0.49 10.8 7.1 0.095 13.0 1.8 2.5 2 1 0 2 2 2 0 HalX domain CBM_3 PF00942.18 OWF43110.1 - 0.51 10.8 2.6 0.42 11.1 0.3 2.0 2 0 0 2 2 1 0 Cellulose binding domain FlaC_arch PF05377.11 OWF43110.1 - 1.4 9.4 13.4 9.6 6.7 0.9 4.3 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) Lipoprotein_6 PF01441.19 OWF43110.1 - 2.2 8.3 12.2 2.8 7.9 1.4 3.0 2 1 1 3 3 3 0 Lipoprotein TMF_TATA_bd PF12325.8 OWF43110.1 - 2.3 8.5 29.6 0.22 11.7 5.8 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding R3H-assoc PF13902.6 OWF43110.1 - 2.3 8.6 12.6 0.28 11.6 7.0 2.3 3 0 0 3 3 3 0 R3H-associated N-terminal domain Fzo_mitofusin PF04799.13 OWF43110.1 - 2.4 7.7 15.2 1.6 8.3 4.9 2.6 1 1 1 2 2 2 0 fzo-like conserved region MCC-bdg_PDZ PF10506.9 OWF43110.1 - 2.6 8.1 17.9 1.4 9.0 0.6 4.4 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Uso1_p115_C PF04871.13 OWF43110.1 - 4.3 7.7 34.6 1.2 9.5 10.7 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mod_r PF07200.13 OWF43110.1 - 4.7 7.3 26.8 1.4 9.1 2.9 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF724 PF05266.14 OWF43110.1 - 6.9 6.4 22.1 0.41 10.5 7.2 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 OWF43110.1 - 7.3 6.0 29.7 0.48 9.9 18.6 2.7 2 1 1 3 3 3 0 Golgin subfamily A member 5 PAS_11 PF14598.6 OWF43111.1 - 4.5e-31 107.3 0.8 3.9e-25 88.2 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 OWF43111.1 - 1.9e-25 89.0 0.1 3.7e-17 62.4 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 OWF43111.1 - 5.5e-21 74.7 0.0 1.4e-11 44.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OWF43111.1 - 1e-09 38.6 0.0 0.00013 22.2 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OWF43111.1 - 3.7e-06 27.2 0.0 0.035 14.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 OWF43111.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_2 PF08446.11 OWF43111.1 - 0.022 15.4 0.0 0.062 14.0 0.0 1.7 2 0 0 2 2 2 0 PAS fold FWWh PF14922.6 OWF43112.1 - 9.9e-51 171.5 1.8 2e-50 170.5 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 PF01519.16 OWF43112.1 - 0.13 12.7 3.1 0.76 10.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 7tm_1 PF00001.21 OWF43113.1 - 1.4e-22 80.3 11.0 1.9e-22 79.9 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF43113.1 - 1.7e-10 40.7 14.2 3.1e-09 36.6 14.2 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF43113.1 - 1.3e-05 25.0 16.6 2.9e-05 23.8 16.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 OWF43113.1 - 0.0057 16.3 18.3 0.019 14.7 18.3 1.8 1 1 0 1 1 1 1 Srg family chemoreceptor Glutaredoxin PF00462.24 OWF43114.1 - 5.9e-18 64.8 0.0 8.7e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 OWF43114.1 - 0.0022 18.4 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 OWF43114.1 - 0.0038 17.2 0.0 0.008 16.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 OWF43114.1 - 0.0043 17.4 0.0 0.0054 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 OWF43114.1 - 0.01 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 OWF43114.1 - 0.064 13.4 0.3 3.7 7.7 0.3 2.2 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 OWF43114.1 - 0.069 13.6 0.2 0.12 12.8 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain AFT PF08731.11 OWF43114.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcription factor AFT SRP-alpha_N PF04086.13 OWF43115.1 - 0.5 10.2 5.7 0.66 9.8 5.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NOC3p PF07540.11 OWF43118.1 - 7.7e-26 90.4 0.6 7.7e-26 90.4 0.6 3.2 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 OWF43118.1 - 8.5e-24 84.5 0.3 8.5e-24 84.5 0.3 3.0 3 1 0 3 3 3 1 CBF/Mak21 family DUF853 PF05872.12 OWF43118.1 - 0.18 10.3 10.2 0.44 9.1 0.2 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) COG2 PF06148.11 OWF43118.1 - 3.5 7.7 9.5 0.62 10.2 4.6 2.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 REJ PF02010.15 OWF43119.1 - 3.8e-24 85.3 14.0 2.7e-13 49.5 0.2 3.9 3 1 1 4 4 4 3 REJ domain Gal_Lectin PF02140.18 OWF43119.1 - 6.5e-23 81.0 4.4 6.5e-23 81.0 4.4 2.1 2 0 0 2 2 2 1 Galactose binding lectin domain RPN6_C_helix PF18503.1 OWF43119.1 - 0.037 13.8 2.5 1.5 8.6 0.2 3.0 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain Cyclin PF08613.11 OWF43120.1 - 1e-06 29.2 0.1 9.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 OWF43120.1 - 0.0023 17.7 0.2 0.0023 17.7 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain AMP-binding PF00501.28 OWF43121.1 - 8.5e-92 307.9 0.1 2e-61 207.9 0.1 2.4 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 OWF43121.1 - 5.3e-22 78.7 0.6 5.3e-22 78.7 0.6 2.2 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 OWF43121.1 - 6.1e-05 23.0 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 Gas vesicle protein G PIF1 PF05970.14 OWF43123.1 - 1.8e-23 83.3 0.0 2.4e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OWF43123.1 - 2e-13 50.5 0.0 3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF43123.1 - 3.5e-07 30.6 0.0 6.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF43123.1 - 0.084 13.1 0.1 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain CRF1 PF10380.9 OWF43123.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription factor CRF1 C1q PF00386.21 OWF43124.1 - 5.8e-13 49.2 0.0 1.3e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 C1q domain TMCO5 PF14992.6 OWF43124.1 - 0.015 14.9 0.8 0.019 14.6 0.8 1.1 1 0 0 1 1 1 0 TMCO5 family ZapB PF06005.12 OWF43124.1 - 0.019 15.4 3.7 0.029 14.8 3.7 1.2 1 0 0 1 1 1 0 Cell division protein ZapB zf-CpG_bind_C PF12269.8 OWF43124.1 - 0.039 13.7 0.1 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain YabA PF06156.13 OWF43124.1 - 1.3 9.7 4.8 2.6 8.7 4.7 1.6 1 1 0 1 1 1 0 Initiation control protein YabA DHHC PF01529.20 OWF43125.1 - 2.4e-28 98.9 12.6 2.4e-28 98.9 12.6 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase MFS_1 PF07690.16 OWF43126.1 - 1.7e-08 33.8 2.8 2.5e-08 33.2 2.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3318 PF11780.8 OWF43126.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Laminin_G_2 PF02210.24 OWF43128.1 - 5.6e-138 453.5 27.5 1.4e-17 64.4 0.0 9.4 9 0 0 9 9 9 9 Laminin G domain Laminin_G_1 PF00054.23 OWF43128.1 - 6e-102 337.1 8.1 1e-13 51.6 0.0 9.4 9 0 0 9 9 9 9 Laminin G domain WD40 PF00400.32 OWF43128.1 - 1.3e-16 60.6 6.3 3.4e-08 34.0 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 OWF43128.1 - 3.8e-12 46.6 13.8 0.00017 21.7 0.1 7.7 7 0 0 7 7 7 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 OWF43128.1 - 2e-09 37.6 40.5 3.5e-06 27.2 10.4 3.9 3 0 0 3 3 3 3 EGF-like domain Glyco_hydro_16 PF00722.21 OWF43128.1 - 0.0017 17.8 3.0 1.3 8.4 0.0 4.4 4 0 0 4 4 4 1 Glycosyl hydrolases family 16 ANAPC4_WD40 PF12894.7 OWF43128.1 - 0.0027 17.9 0.1 0.75 10.1 0.1 3.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF43128.1 - 0.0043 15.8 0.8 0.086 11.5 0.1 2.8 2 1 2 4 4 4 1 Nucleoporin Nup120/160 hEGF PF12661.7 OWF43128.1 - 0.0061 17.2 6.8 0.0061 17.2 6.8 4.3 3 0 0 3 3 3 2 Human growth factor-like EGF WD40 PF00400.32 OWF43129.1 - 5.1e-18 65.1 10.9 3.1e-11 43.6 0.5 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF43129.1 - 2.8e-07 30.7 0.2 0.0014 18.9 0.1 3.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OWF43129.1 - 1.4e-06 27.3 0.3 0.0021 16.9 0.1 2.3 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.8 OWF43129.1 - 1.8e-06 26.9 0.9 0.013 14.1 0.0 4.0 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF43129.1 - 0.00056 19.3 0.0 0.00097 18.5 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 OWF43129.1 - 0.012 14.2 0.1 0.033 12.7 0.1 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 OWF43129.1 - 0.086 11.7 2.2 9 5.1 0.1 3.4 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Laminin_G_2 PF02210.24 OWF43130.1 - 4.4e-121 398.9 26.6 1.6e-22 80.4 0.0 11.7 12 0 0 12 12 12 11 Laminin G domain Laminin_G_1 PF00054.23 OWF43130.1 - 2.4e-83 276.9 4.5 5.9e-19 68.6 0.0 10.2 10 0 0 10 10 10 8 Laminin G domain Laminin_G_3 PF13385.6 OWF43130.1 - 1e-74 249.8 41.2 5.9e-16 59.0 0.1 12.0 12 0 0 12 12 12 10 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.11 OWF43130.1 - 3.5e-06 27.3 12.8 0.32 11.1 0.3 7.2 8 0 0 8 8 8 3 Domain of Unknown Function (DUF1080) DED PF01335.21 OWF43132.1 - 2.4e-06 27.7 0.2 0.041 14.2 0.0 2.5 2 0 0 2 2 2 2 Death effector domain Thg1C PF14413.6 OWF43132.1 - 0.4 10.9 4.4 0.85 9.8 4.4 1.6 1 1 0 1 1 1 0 Thg1 C terminal domain ATP-synt_F6 PF05511.11 OWF43132.1 - 0.45 10.9 4.9 2.3 8.7 0.6 2.7 2 1 1 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 Glyco_transf_11 PF01531.16 OWF43133.1 - 0.00061 19.1 0.0 0.0014 17.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 11 XG_FTase PF03254.13 OWF43133.1 - 0.032 12.9 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Organ_specific PF10950.8 OWF43133.1 - 0.13 13.0 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 Organ specific protein Laminin_G_3 PF13385.6 OWF43134.1 - 0.004 17.3 0.1 0.025 14.7 0.1 2.2 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4978 PF16349.5 OWF43135.1 - 5.8 6.5 17.2 1.8e+04 -6.2 17.2 3.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4978) FCH PF00611.23 OWF43136.1 - 3.9e-17 62.3 3.0 5.2e-17 61.9 0.3 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 OWF43136.1 - 2.6e-14 52.8 0.2 5e-14 51.9 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF43136.1 - 6.4e-13 48.1 0.1 1.2e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF43136.1 - 9.7e-13 47.6 0.0 1.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 OWF43136.1 - 1.5e-05 25.0 0.8 1.5e-05 25.0 0.8 2.8 3 0 0 3 3 3 1 Hr1 repeat betaPIX_CC PF16523.5 OWF43136.1 - 0.047 13.5 0.7 0.047 13.5 0.7 3.4 4 0 0 4 4 4 0 betaPIX coiled coil DUF836 PF05768.14 OWF43136.1 - 0.12 12.8 4.0 13 6.2 1.0 3.0 2 1 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Tox-REase-5 PF15648.6 OWF43136.1 - 0.36 11.4 2.2 0.61 10.6 0.9 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 Rotamase_2 PF13145.6 OWF43136.1 - 3.7 8.4 13.4 2.4 9.0 0.2 2.9 3 0 0 3 3 3 0 PPIC-type PPIASE domain CS PF04969.16 OWF43137.1 - 3.3e-10 40.9 0.3 4.1e-10 40.5 0.3 1.1 1 0 0 1 1 1 1 CS domain ABC_tran PF00005.27 OWF43138.1 - 1.4e-46 158.4 0.0 1.2e-23 84.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OWF43138.1 - 2.9e-20 72.1 3.9 2.9e-20 72.1 3.9 3.1 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 OWF43138.1 - 5e-18 65.9 4.2 0.00026 20.9 0.1 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF43138.1 - 3.1e-10 39.8 0.2 0.0056 16.1 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OWF43138.1 - 5.1e-07 29.7 2.1 0.004 16.9 0.1 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 OWF43138.1 - 3e-06 26.9 0.0 0.0055 16.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OWF43138.1 - 0.00011 22.2 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 OWF43138.1 - 0.00013 22.2 0.1 0.12 12.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 OWF43138.1 - 0.00042 20.4 0.0 0.18 11.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OWF43138.1 - 0.0015 19.1 11.2 0.0076 16.8 0.1 3.8 4 0 0 4 4 3 1 AAA domain DUF2813 PF11398.8 OWF43138.1 - 0.002 17.5 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_18 PF13238.6 OWF43138.1 - 0.002 18.7 0.2 0.67 10.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 OWF43138.1 - 0.002 18.4 0.0 0.78 10.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF43138.1 - 0.004 17.5 0.0 0.64 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OWF43138.1 - 0.0066 16.9 0.0 0.28 11.6 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OWF43138.1 - 0.0077 16.0 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 OWF43138.1 - 0.01 15.8 0.0 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OWF43138.1 - 0.02 14.8 0.5 0.83 9.6 0.1 2.5 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OWF43138.1 - 0.032 14.0 0.0 0.88 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OWF43138.1 - 0.041 13.5 0.0 1 8.9 0.0 2.8 4 0 0 4 4 3 0 AAA domain AAA_22 PF13401.6 OWF43138.1 - 0.041 14.1 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 OWF43138.1 - 0.045 13.3 0.1 1.7 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OWF43138.1 - 0.055 13.5 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Dynamin family MukB PF04310.12 OWF43138.1 - 0.082 12.7 0.0 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 MukB N-terminal RNA_helicase PF00910.22 OWF43138.1 - 0.091 13.2 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 OWF43138.1 - 0.13 12.3 0.2 3.7 7.5 0.1 2.6 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) UCH PF00443.29 OWF43139.1 - 2.6e-40 138.6 0.0 5.2e-35 121.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF43139.1 - 7.9e-19 68.4 0.0 7.7e-18 65.2 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OWF43139.1 - 0.00056 19.6 4.6 4.3 7.2 0.1 5.4 6 0 0 6 6 6 1 Ubiquitin family RA PF00788.23 OWF43139.1 - 0.3 11.7 4.8 1.5 9.5 0.0 3.7 4 0 0 4 4 4 0 Ras association (RalGDS/AF-6) domain Ubiquitin_4 PF18036.1 OWF43139.1 - 1 9.5 4.1 50 4.0 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-like domain Ras PF00071.22 OWF43140.1 - 4.8e-55 185.6 0.0 5.5e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43140.1 - 3e-22 79.1 0.0 3.9e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43140.1 - 3.4e-09 36.4 0.0 4.3e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF43140.1 - 2.8e-08 33.5 0.0 9.6e-08 31.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF43140.1 - 0.00011 22.2 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF43140.1 - 0.00019 21.3 0.4 0.0015 18.3 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 OWF43140.1 - 0.00095 18.5 0.0 0.2 10.9 0.0 2.3 1 1 0 2 2 2 2 Septin Gtr1_RagA PF04670.12 OWF43140.1 - 0.0027 17.1 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OWF43140.1 - 0.0041 17.0 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 OWF43140.1 - 0.055 12.6 0.1 0.081 12.1 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 OWF43140.1 - 0.062 13.7 0.1 0.16 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ParA PF10609.9 OWF43140.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase KH_1 PF00013.29 OWF43141.1 - 4.4e-58 193.0 17.4 2e-14 53.2 0.0 4.4 4 0 0 4 4 4 4 KH domain RRM_1 PF00076.22 OWF43141.1 - 3.5e-14 52.4 0.0 4.7e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 OWF43141.1 - 6.9e-13 48.2 9.7 0.00053 19.8 0.2 4.7 5 0 0 5 5 5 3 KH domain KH_4 PF13083.6 OWF43141.1 - 3.4e-11 42.8 2.9 0.057 13.3 0.1 4.4 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 OWF43141.1 - 8.7e-08 32.1 9.9 0.0091 16.1 0.1 4.4 4 0 0 4 4 4 3 NusA-like KH domain RRM_5 PF13893.6 OWF43141.1 - 8.2e-06 25.4 0.0 0.012 15.2 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOEP19 PF16005.5 OWF43141.1 - 0.00022 21.1 0.1 1.1 9.2 0.0 3.4 4 0 0 4 4 4 2 KH-like RNA-binding domain DbpA PF03880.15 OWF43141.1 - 0.018 15.0 0.1 0.21 11.6 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain CooC_C PF15976.5 OWF43141.1 - 0.19 11.8 2.4 6.4 6.9 0.0 3.7 3 1 1 4 4 4 0 CS1-pili formation C-terminal PID PF00640.23 OWF43142.1 - 1e-37 129.3 0.0 1.4e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 OWF43142.1 - 5.1e-19 68.1 0.0 9.9e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SHIPPO-rpt PF07004.12 OWF43143.1 - 5.9e-13 49.1 32.5 0.01 16.7 1.0 6.4 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat Abhydrolase_6 PF12697.7 OWF43144.1 - 2.9e-06 28.0 0.0 3.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF43144.1 - 3.4e-06 26.9 0.0 1.6e-05 24.7 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 OWF43144.1 - 5e-06 26.8 0.1 7.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 OWF43144.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.8 OWF43144.1 - 0.015 14.5 0.0 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OWF43144.1 - 0.029 14.1 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 OWF43144.1 - 0.18 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DNApol3-delta_C PF09115.10 OWF43145.1 - 7e-14 52.3 66.7 11 6.6 0.2 18.8 1 1 33 35 35 35 25 DNA polymerase III, delta subunit, C terminal Rad33 PF08730.10 OWF43145.1 - 8.7e-08 32.3 29.0 2.4 8.1 1.0 8.7 1 1 6 9 9 9 9 Rad33 CREPT PF16566.5 OWF43145.1 - 5.4e-05 23.4 94.2 29 4.8 0.9 17.3 1 1 30 31 31 31 21 Cell-cycle alteration and expression-elevated protein in tumour Connexin40_C PF16791.5 OWF43145.1 - 0.061 14.6 17.5 2.5e+02 3.0 0.0 11.1 1 1 11 13 13 13 0 Connexin 40 C-terminal domain DUF1618 PF07762.14 OWF43145.1 - 0.4 11.3 25.9 1.8e+02 2.7 0.3 8.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1618) Ribosomal_L34 PF00468.17 OWF43146.1 - 0.00014 21.7 3.1 0.00014 21.7 3.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L34 Abhydrolase_1 PF00561.20 OWF43147.1 - 7.4e-26 91.3 0.6 1.4e-20 74.0 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF43147.1 - 1.3e-17 65.1 0.2 1.6e-16 61.6 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF43147.1 - 1.4e-17 63.8 0.1 1.2e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OWF43147.1 - 3.1e-06 27.1 0.0 0.0033 17.3 0.0 2.5 2 0 0 2 2 2 2 Serine hydrolase FSH1 PF03959.13 OWF43147.1 - 0.00037 20.2 0.0 0.0014 18.3 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 OWF43147.1 - 0.0024 16.8 0.0 0.0059 15.6 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 OWF43147.1 - 0.0033 17.3 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.16 OWF43147.1 - 0.0053 16.6 0.5 9 6.0 0.0 3.2 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 OWF43147.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 OWF43147.1 - 0.12 12.4 0.5 0.61 10.2 0.1 2.3 2 1 0 2 2 2 0 Thioesterase domain MFS_1 PF07690.16 OWF43148.1 - 2.6e-19 69.4 31.3 1.7e-16 60.1 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 OWF43148.1 - 3.4e-17 62.1 22.3 3.6e-15 55.5 11.8 3.2 2 1 0 2 2 2 1 Acetyl-coenzyme A transporter 1 OATP PF03137.20 OWF43148.1 - 1.4e-05 23.6 5.9 7e-05 21.3 3.9 2.6 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Transgly_assoc PF04226.13 OWF43148.1 - 0.042 14.1 2.6 0.1 12.9 0.6 2.8 2 0 0 2 2 2 0 Transglycosylase associated protein DUF5353 PF17304.2 OWF43148.1 - 1.6 8.5 4.1 6 6.7 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5353) RRM_1 PF00076.22 OWF43149.1 - 9.3e-11 41.4 0.2 5.6e-09 35.7 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GMC_oxred_N PF00732.19 OWF43150.1 - 1.9e-83 280.3 0.0 2.5e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF43150.1 - 6.4e-37 127.3 0.4 1e-36 126.6 0.4 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF43150.1 - 5.7e-08 32.3 0.0 0.00038 19.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OWF43150.1 - 3.2e-05 24.1 0.1 8.2e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OWF43150.1 - 0.013 14.7 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF43150.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 OWF43150.1 - 0.022 14.4 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OWF43150.1 - 0.087 11.5 0.0 0.25 10.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 OWF43150.1 - 0.19 11.4 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lipase_GDSL_2 PF13472.6 OWF43151.1 - 0.0061 17.0 0.0 0.0073 16.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GMC_oxred_N PF00732.19 OWF43152.1 - 7.3e-85 284.9 0.0 9.4e-85 284.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF43152.1 - 2.6e-42 144.8 0.0 4.6e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF43152.1 - 6.8e-06 25.4 0.0 0.0067 15.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OWF43152.1 - 0.00017 21.8 0.1 0.00039 20.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF43152.1 - 0.013 14.7 0.1 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 OWF43152.1 - 0.014 15.0 0.0 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 OWF43152.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 OWF43152.1 - 0.084 12.1 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF43152.1 - 0.086 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TNFR_16_TM PF18422.1 OWF43152.1 - 0.089 12.8 0.9 0.19 11.7 0.9 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain GMC_oxred_N PF00732.19 OWF43153.1 - 3.4e-92 309.0 0.0 4.4e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF43153.1 - 9.9e-41 139.6 0.0 1.6e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF43153.1 - 1.3e-05 24.5 0.0 0.0097 15.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OWF43153.1 - 0.00085 19.5 0.1 0.0028 17.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF43153.1 - 0.014 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 OWF43153.1 - 0.016 14.8 0.1 0.1 12.2 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF43153.1 - 0.042 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OWF43153.1 - 0.088 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Alk_phosphatase PF00245.20 OWF43155.1 - 1.2e-92 311.0 4.7 2.1e-90 303.7 4.7 2.8 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF43155.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Misat_Tub_SegII PF10644.9 OWF43159.1 - 2.1e-38 131.2 0.2 5.2e-38 130.0 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OWF43159.1 - 4.3e-29 101.5 0.0 7.5e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 OWF43159.1 - 4e-09 37.0 0.0 0.00049 20.4 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF2478 PF10649.9 OWF43159.1 - 0.2 11.3 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) ribosomal_L24 PF17136.4 OWF43161.1 - 8.2e-11 42.1 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 OWF43161.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 KOW motif Snurportin1 PF11538.8 OWF43162.1 - 2.6e-12 46.7 1.7 6.4e-12 45.5 1.7 1.7 1 0 0 1 1 1 1 Snurportin1 mRNA_cap_enzyme PF01331.19 OWF43162.1 - 3.1e-06 27.1 0.1 0.016 15.1 0.1 2.5 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain Pkinase PF00069.25 OWF43163.1 - 2e-23 83.1 0.5 2.3e-23 82.9 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF43163.1 - 3.5e-10 39.6 0.1 4e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 OWF43164.1 - 1.2e-41 142.0 0.1 1.5e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43164.1 - 8.3e-16 58.3 0.0 1.2e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43164.1 - 7.5e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF43164.1 - 1.5e-05 25.1 0.0 2.9e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF43164.1 - 4.4e-05 23.4 0.2 0.019 14.9 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OWF43164.1 - 5.5e-05 22.8 0.4 0.00064 19.3 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DDE_3 PF13358.6 OWF43164.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease G-alpha PF00503.20 OWF43164.1 - 0.09 11.9 0.0 3.9 6.5 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit SIR2 PF02146.17 OWF43165.1 - 1.2e-64 217.4 0.0 3.1e-64 216.1 0.0 1.7 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 OWF43165.1 - 0.0084 15.9 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) NHase_alpha PF02979.16 OWF43165.1 - 0.042 13.2 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain TPP_enzyme_M PF00205.22 OWF43165.1 - 0.18 11.5 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DnaJ PF00226.31 OWF43166.1 - 4.7e-21 74.7 1.2 8.2e-21 73.9 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF5082 PF16888.5 OWF43166.1 - 0.015 15.6 1.2 0.038 14.3 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Takusan PF04822.13 OWF43166.1 - 0.066 13.1 0.3 0.066 13.1 0.3 1.8 2 0 0 2 2 2 0 Takusan Atx10homo_assoc PF09759.9 OWF43166.1 - 0.074 13.1 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Ribosomal_S24e PF01282.19 OWF43166.1 - 0.092 12.7 0.2 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein S24e Xpo1 PF08389.12 OWF43168.1 - 1e-20 74.3 9.9 5.9e-11 42.6 0.0 7.0 5 1 3 8 8 8 3 Exportin 1-like protein IBN_N PF03810.19 OWF43168.1 - 6.2e-06 26.0 1.7 5.5e-05 23.0 0.2 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Peptidase_C11 PF03415.14 OWF43168.1 - 0.17 11.2 0.5 0.58 9.5 0.2 1.8 2 0 0 2 2 2 0 Clostripain family UNC45-central PF11701.8 OWF43168.1 - 0.43 10.5 4.5 6.8 6.6 0.1 4.1 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central Tom22 PF04281.13 OWF43169.1 - 1.5e-10 41.0 0.0 1.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NUDIX PF00293.28 OWF43171.1 - 3.3e-18 66.0 0.0 5.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_20 PF00728.22 OWF43172.1 - 7.8e-74 249.2 1.5 3.1e-53 181.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OWF43172.1 - 4.4e-19 69.5 0.0 6.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OWF43172.1 - 0.0017 19.1 0.0 0.0033 18.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 SLH PF00395.20 OWF43172.1 - 0.03 14.3 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 S-layer homology domain Anoctamin PF04547.12 OWF43173.1 - 2.7e-158 527.5 9.6 3.3e-158 527.2 9.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OWF43173.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Babuvirus_MP PF07234.11 OWF43173.1 - 9.9 6.4 6.8 6.4 7.0 2.6 2.5 2 0 0 2 2 2 0 Movement and RNA silencing protein LSDAT_euk PF18139.1 OWF43174.1 - 4.8e-35 121.2 0.0 8.9e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 OWF43174.1 - 5.7e-21 74.4 5.6 1.8e-20 72.8 5.6 1.9 1 0 0 1 1 1 1 Tetramerisation domain of TRPM Ion_trans PF00520.31 OWF43174.1 - 4e-15 55.7 17.6 6.3e-15 55.1 17.6 1.3 1 0 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 OWF43174.1 - 0.0021 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote PKD_channel PF08016.12 OWF43174.1 - 0.0023 16.7 4.3 0.0023 16.7 4.3 2.2 1 1 1 2 2 2 1 Polycystin cation channel Ank_2 PF12796.7 OWF43174.1 - 0.023 15.2 0.1 5.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) XhlA PF10779.9 OWF43174.1 - 7.4 6.9 8.9 1.1 9.6 4.3 2.0 2 0 0 2 2 2 0 Haemolysin XhlA LSDAT_euk PF18139.1 OWF43176.1 - 2.4e-79 266.5 0.1 3.2e-79 266.1 0.1 1.1 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF43176.1 - 9.4e-15 54.4 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote DNApol_Exo PF18136.1 OWF43177.1 - 1.3e-98 329.6 1.0 2.5e-98 328.7 1.0 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OWF43177.1 - 6.2e-51 173.6 0.0 1.1e-50 172.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_B_2 PF03175.13 OWF43177.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 OWF43177.1 - 0.029 14.1 0.4 0.19 11.4 0.4 2.2 1 1 0 1 1 1 0 3'-5' exonuclease SRCR PF00530.18 OWF43178.1 - 0 1164.2 131.3 7.1e-27 93.8 0.3 21.1 21 0 0 21 21 21 21 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF43178.1 - 8.7e-70 231.4 110.5 7.3e-06 26.4 3.8 20.8 20 0 0 20 20 20 19 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF43178.1 - 1.9e-31 108.8 49.4 0.025 15.1 2.2 18.8 19 0 0 19 19 19 12 Hepsin, SRCR domain DUF5305 PF17231.2 OWF43178.1 - 0.00028 20.3 9.6 0.00048 19.6 9.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Str_synth PF03088.16 OWF43178.1 - 0.0065 16.6 0.0 24 5.1 0.0 4.7 4 0 0 4 4 4 1 Strictosidine synthase DUF2207 PF09972.9 OWF43178.1 - 0.011 14.5 0.9 0.019 13.8 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 OWF43178.1 - 0.02 14.4 0.4 0.035 13.7 0.4 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame PRAS PF15798.5 OWF43179.1 - 0.0071 16.9 38.1 55 4.4 0.1 12.1 1 1 14 15 15 15 1 Proline-rich AKT1 substrate 1 BaffR-Tall_bind PF09256.10 OWF43179.1 - 0.13 12.0 97.1 0.25 11.2 1.6 12.3 3 1 13 16 16 16 0 BAFF-R, TALL-1 binding GF_recep_IV PF14843.6 OWF43179.1 - 6.3 6.6 25.9 34 4.2 2.0 5.0 2 2 1 3 3 3 0 Growth factor receptor domain IV Ig_3 PF13927.6 OWF43180.1 - 9.2e-20 71.0 0.5 5.5e-10 39.7 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF43180.1 - 1e-18 67.2 0.0 4.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 OWF43180.1 - 1.8e-16 60.3 0.2 6.4e-10 39.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 OWF43180.1 - 1.7e-13 50.6 0.2 4.2e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF43180.1 - 2.9e-10 40.3 1.1 0.00023 21.4 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 OWF43180.1 - 3.5e-05 23.3 0.0 0.29 10.7 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 OWF43180.1 - 0.00025 21.4 0.2 0.039 14.3 0.1 3.1 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 OWF43180.1 - 0.00025 21.4 0.1 0.0039 17.6 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 OWF43180.1 - 0.00039 20.6 0.1 3.6 7.9 0.0 3.3 2 1 1 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 OWF43180.1 - 0.012 15.6 0.1 5.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain IL17R_fnIII_D1 PF16556.5 OWF43180.1 - 0.029 14.0 0.1 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 C2-set_2 PF08205.12 OWF43180.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain PSI PF01437.25 OWF43181.1 - 0.082 13.5 1.4 15 6.2 0.1 2.5 2 0 0 2 2 2 0 Plexin repeat DUF4187 PF13821.6 OWF43181.1 - 0.15 11.8 4.9 5.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) PSI_integrin PF17205.3 OWF43181.1 - 0.16 11.7 2.3 11 5.9 0.1 2.3 2 0 0 2 2 2 0 Integrin plexin domain DUF3973 PF13119.6 OWF43181.1 - 0.6 10.2 8.5 57 3.9 1.1 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF3973) DUF2946 PF11162.8 OWF43181.1 - 3.5 8.3 5.1 12 6.6 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) DUF3961 PF13106.6 OWF43181.1 - 3.7 7.3 8.4 13 5.5 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3961) Nucleoside_tran PF01733.18 OWF43182.1 - 1.2e-64 218.6 22.1 5e-64 216.6 22.1 1.9 1 1 0 1 1 1 1 Nucleoside transporter PCI PF01399.27 OWF43183.1 - 7.1e-14 52.2 0.1 7.1e-14 52.2 0.1 3.6 3 0 0 3 3 3 1 PCI domain SPA PF08616.10 OWF43184.1 - 7.2e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 OWF43184.1 - 1.1e-07 31.7 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 OWF43184.1 - 1.9e-06 26.8 0.0 9.1e-05 21.3 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 CutC PF03932.14 OWF43185.1 - 7.8e-68 227.9 0.0 9.7e-68 227.6 0.0 1.1 1 0 0 1 1 1 1 CutC family 7tm_1 PF00001.21 OWF43186.1 - 1.8e-45 155.4 23.6 1.8e-45 155.4 23.6 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF43186.1 - 1.5e-08 34.4 23.0 2.3e-08 33.7 23.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx B12-binding PF02310.19 OWF43187.1 - 1.3e-16 60.7 0.0 2.4 8.2 0.0 10.4 1 1 10 11 11 11 7 B12 binding domain TPKR_C2 PF16920.5 OWF43187.1 - 1e-13 51.2 29.3 4.9 7.4 0.1 10.8 2 1 9 11 11 11 8 Tyrosine-protein kinase receptor C2 Ig-like domain TFIID_NTD2 PF04494.15 OWF43187.1 - 1.2e-08 35.3 35.1 25 5.1 0.1 11.6 1 1 11 12 12 12 0 WD40 associated region in TFIID subunit, NTD2 domain Ribosomal_S27 PF01599.19 OWF43187.1 - 2.3e-08 34.1 19.7 10 6.4 0.0 11.4 13 0 0 13 13 13 1 Ribosomal protein S27a Methyltransf_FA PF12248.8 OWF43187.1 - 1.8e-06 28.2 15.6 0.34 11.3 0.4 4.7 1 1 7 8 8 8 7 Farnesoic acid 0-methyl transferase CCDC168_N PF15804.5 OWF43187.1 - 0.00018 21.5 14.9 0.51 10.2 0.9 4.4 1 1 6 7 7 7 5 Coiled-coil domain-containing protein 168 LCE PF14672.6 OWF43187.1 - 0.0021 18.6 59.0 4.4 8.0 1.9 10.8 1 1 10 12 12 12 9 Late cornified envelope zf-UBP PF02148.19 OWF43187.1 - 1.1 9.7 56.5 23 5.4 5.3 8.5 1 1 8 9 9 9 0 Zn-finger in ubiquitin-hydrolases and other protein PAZ PF02170.22 OWF43187.1 - 5.3 6.8 22.4 1.8e+04 -12.6 22.3 6.4 1 1 0 1 1 1 0 PAZ domain DUF2612 PF11041.8 OWF43189.1 - 1.1 9.2 20.9 1.6 8.6 0.6 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF2612) YrhK PF14145.6 OWF43190.1 - 9.9e-15 54.2 96.7 0.014 15.2 9.4 10.9 1 1 4 5 5 5 3 YrhK-like protein DUF1218 PF06749.12 OWF43190.1 - 8.2e-06 26.3 104.1 0.22 12.1 5.6 10.1 1 1 8 9 9 9 8 Protein of unknown function (DUF1218) WYL_2 PF10902.8 OWF43190.1 - 0.00053 20.3 23.4 1.3e+02 3.0 0.2 12.9 1 1 7 9 9 9 0 WYL_2, Sm-like SH3 beta-barrel fold Claudin_3 PF06653.11 OWF43191.1 - 1.2e-05 25.3 6.5 1.7e-05 24.8 6.5 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 OWF43191.1 - 0.00024 20.9 12.3 0.35 10.6 0.1 3.1 1 1 2 3 3 3 3 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF43191.1 - 0.0003 20.7 6.2 0.0009 19.2 5.4 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 OWF43191.1 - 0.022 14.6 4.7 0.018 14.9 3.0 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF2157 PF09925.9 OWF43191.1 - 0.062 13.1 0.4 0.062 13.1 0.4 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF3087 PF11286.8 OWF43191.1 - 0.21 11.1 5.7 0.062 12.8 1.8 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) MDM31_MDM32 PF08118.11 OWF43191.1 - 0.35 9.5 1.8 0.53 8.9 1.8 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Synthase_beta PF11421.8 OWF43192.1 - 0.21 12.3 1.5 2.1 9.1 0.0 2.6 2 1 0 2 2 2 0 ATP synthase F1 beta subunit CRAL_TRIO PF00650.20 OWF43193.1 - 2.1e-33 115.3 0.0 3.2e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 OWF43193.1 - 7.5e-12 45.9 0.3 7.1e-06 26.6 0.0 2.5 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 OWF43193.1 - 5.2e-07 29.9 0.1 4.8e-05 23.5 0.0 2.7 2 1 1 3 3 3 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 OWF43194.1 - 3.4e-40 137.3 0.2 6.3e-40 136.5 0.1 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain GOLD_2 PF13897.6 OWF43194.1 - 3.3e-07 30.9 1.9 0.0024 18.4 0.0 2.5 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 OWF43194.1 - 5e-07 29.8 0.2 1.2e-06 28.6 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OWF43194.1 - 6.3e-05 23.2 0.1 0.00012 22.3 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UN_NPL4 PF11543.8 OWF43194.1 - 0.058 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Anp1 PF03452.14 OWF43195.1 - 6.5e-49 166.7 0.0 9.4e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 OWF43195.1 - 1.1e-07 31.8 0.0 1.8e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 CAP59_mtransfer PF11735.8 OWF43195.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_3 PF13641.6 OWF43195.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 TFIID_30kDa PF03540.13 OWF43196.1 - 4.1e-27 93.9 0.0 7.2e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 OWF43196.1 - 0.005 16.8 0.0 0.054 13.5 0.0 2.1 1 1 0 1 1 1 1 Bromodomain associated SLX9 PF15341.6 OWF43196.1 - 0.017 15.5 0.2 0.025 15.0 0.2 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF2420 PF10336.9 OWF43196.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) ABC_membrane PF00664.23 OWF43197.1 - 4.2e-129 430.0 26.8 2.6e-70 237.2 7.6 2.5 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF43197.1 - 1.9e-73 245.4 0.0 3.3e-35 121.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF43197.1 - 1.4e-19 70.5 0.0 2.6e-08 33.6 0.0 4.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OWF43197.1 - 3.7e-09 35.9 0.4 0.001 18.0 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 OWF43197.1 - 6.3e-09 36.4 5.3 0.0018 18.7 0.4 3.9 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OWF43197.1 - 2.8e-08 33.9 0.0 0.0032 17.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OWF43197.1 - 1.7e-07 31.6 0.5 0.0061 16.8 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 OWF43197.1 - 7.4e-07 29.7 0.0 0.0097 16.3 0.0 3.6 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OWF43197.1 - 1.3e-06 28.2 0.1 0.012 15.4 0.1 3.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OWF43197.1 - 1.8e-06 27.6 0.2 0.066 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OWF43197.1 - 4.4e-06 26.1 0.0 0.054 12.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 OWF43197.1 - 8.2e-06 25.9 0.2 0.072 13.0 0.0 2.6 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_7 PF12775.7 OWF43197.1 - 1.1e-05 25.0 0.1 0.035 13.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OWF43197.1 - 5e-05 23.1 0.7 0.14 11.9 0.0 3.5 4 0 0 4 4 4 1 IstB-like ATP binding protein G-alpha PF00503.20 OWF43197.1 - 5.6e-05 22.5 0.0 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit ATP-synt_ab PF00006.25 OWF43197.1 - 5.6e-05 22.9 0.3 0.33 10.6 0.1 2.7 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.6 OWF43197.1 - 0.00014 21.8 0.1 1.5 8.6 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OWF43197.1 - 0.00016 21.7 0.2 0.26 11.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 OWF43197.1 - 0.0002 21.5 4.0 0.47 10.7 0.4 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 OWF43197.1 - 0.00029 21.4 0.0 0.86 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OWF43197.1 - 0.00035 20.9 0.1 1.8 8.8 0.1 3.3 2 1 0 3 3 3 1 AAA domain PRK PF00485.18 OWF43197.1 - 0.00067 19.4 0.0 0.9 9.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 OWF43197.1 - 0.00088 18.9 0.5 2.1 7.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 OWF43197.1 - 0.00093 19.6 0.0 1.3 9.4 0.0 2.9 2 0 0 2 2 2 1 RNA helicase APS_kinase PF01583.20 OWF43197.1 - 0.0012 18.8 0.1 0.44 10.4 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 OWF43197.1 - 0.0021 18.2 0.0 2.2 8.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 OWF43197.1 - 0.0022 17.8 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OWF43197.1 - 0.0024 17.1 0.1 1.9 7.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_15 PF13175.6 OWF43197.1 - 0.0026 17.6 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OWF43197.1 - 0.0038 17.7 2.5 10 6.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 OWF43197.1 - 0.0068 16.5 0.0 4.7 7.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 OWF43197.1 - 0.0081 16.2 0.0 11 6.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.13 OWF43197.1 - 0.0093 15.1 0.0 1.2 8.2 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ArsP_1 PF03773.13 OWF43197.1 - 0.0098 15.1 2.6 0.064 12.4 0.3 2.5 2 0 0 2 2 2 1 Predicted permease Sigma54_activat PF00158.26 OWF43197.1 - 0.012 15.3 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CDC45 PF02724.14 OWF43197.1 - 0.013 13.8 10.7 0.022 13.1 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF87 PF01935.17 OWF43197.1 - 0.014 15.5 0.1 7.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Aim21 PF11489.8 OWF43197.1 - 0.039 12.9 3.7 0.054 12.4 3.7 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 MeaB PF03308.16 OWF43197.1 - 0.051 12.5 0.0 4.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 OWF43197.1 - 0.055 13.4 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain tRNA_lig_kinase PF08303.11 OWF43197.1 - 0.06 13.4 0.1 4.3 7.4 0.0 2.7 3 0 0 3 3 2 0 tRNA ligase kinase domain Mg_chelatase PF01078.21 OWF43197.1 - 0.068 12.5 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI mono-CXXC PF15626.6 OWF43199.1 - 0.11 12.9 2.4 8.7 6.8 0.2 2.8 1 1 2 3 3 3 0 single CXXC unit MFS_1 PF07690.16 OWF43201.1 - 2.7e-33 115.4 42.3 6.4e-26 91.1 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF43201.1 - 9.1e-10 38.4 26.4 1.6e-09 37.5 26.4 1.4 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 OWF43202.1 - 7e-23 81.1 51.3 6.3e-13 48.4 31.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM173 PF15009.6 OWF43202.1 - 3.4 6.7 4.3 1 8.4 1.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 173 zf-B_box PF00643.24 OWF43203.1 - 3.4e-09 36.7 31.9 1.7e-05 24.8 9.4 3.9 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF43203.1 - 1.9e-06 27.6 8.9 1.9e-06 27.6 8.9 4.2 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF43203.1 - 3.4e-06 26.9 37.8 9.2e-06 25.5 8.3 4.1 4 0 0 4 4 4 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF43203.1 - 2e-05 24.5 6.2 2e-05 24.5 6.2 4.2 4 1 0 4 4 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF43203.1 - 7.9e-05 22.9 8.7 7.9e-05 22.9 8.7 4.6 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF43203.1 - 0.00037 20.3 6.7 0.00037 20.3 6.7 4.0 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Apolipoprotein PF01442.18 OWF43203.1 - 0.0012 18.8 3.4 0.002 18.0 3.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain zf-C3HC4_2 PF13923.6 OWF43203.1 - 0.003 17.4 9.1 0.003 17.4 9.1 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OWF43203.1 - 0.0059 16.4 6.6 0.0059 16.4 6.6 3.7 4 0 0 4 4 4 2 RING/Ubox like zinc-binding domain CRIC_ras_sig PF10534.9 OWF43203.1 - 0.067 13.4 0.8 0.17 12.1 0.8 1.6 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras Aida_N PF08910.10 OWF43203.1 - 0.27 11.7 5.2 0.7 10.3 2.5 2.5 1 1 1 2 2 2 0 Aida N-terminus DUF1664 PF07889.12 OWF43203.1 - 3.9 7.5 5.5 3.7 7.6 3.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 OWF43204.1 - 4e-26 91.8 45.5 2.7e-23 82.5 37.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SlyX PF04102.12 OWF43205.1 - 0.029 15.0 19.4 1.2 9.9 4.0 3.9 2 1 2 4 4 4 0 SlyX DUF2309 PF10070.9 OWF43205.1 - 0.034 12.5 1.5 0.046 12.1 1.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Bcl-2_3 PF15286.6 OWF43205.1 - 0.043 14.5 0.1 0.19 12.4 0.0 2.1 1 1 1 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Fez1 PF06818.15 OWF43205.1 - 0.12 12.8 28.6 0.21 12.0 10.0 2.2 1 1 1 2 2 2 0 Fez1 Tropomyosin PF00261.20 OWF43205.1 - 0.17 11.2 30.7 0.035 13.5 16.9 3.0 1 1 2 3 3 3 0 Tropomyosin Syntaxin PF00804.25 OWF43205.1 - 0.31 10.7 23.3 0.052 13.2 14.5 2.8 1 1 2 3 3 3 0 Syntaxin DUF745 PF05335.13 OWF43205.1 - 1.4 8.6 12.2 1.5 8.5 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.12 OWF43205.1 - 1.7 8.7 21.7 4.2 7.4 2.5 3.2 1 1 2 3 3 3 0 Laminin Domain II Atg14 PF10186.9 OWF43205.1 - 3.8 6.5 18.3 1.8 7.6 4.9 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 OWF43205.1 - 7.2 6.8 19.6 0.45 10.6 3.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 OWF43205.1 - 7.3 4.4 25.9 1.2 7.0 2.2 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family GerA PF03323.13 OWF43206.1 - 1.8 7.0 4.2 3.4 6.0 4.2 1.4 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein NAD_binding_4 PF07993.12 OWF43207.1 - 1.5e-74 250.4 0.0 1.9e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 OWF43207.1 - 5.1e-31 106.7 1.9 1.5e-30 105.2 1.9 1.9 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OWF43207.1 - 1.8e-08 34.1 0.0 1.2e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OWF43207.1 - 2.5e-05 23.6 0.0 3.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OWF43207.1 - 5.6e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OWF43207.1 - 0.0015 17.6 0.0 0.0089 15.1 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family IPPT PF01715.17 OWF43207.1 - 0.0062 16.4 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 IPP transferase KR PF08659.10 OWF43207.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 KR domain PNISR PF15996.5 OWF43208.1 - 0.012 15.9 5.2 0.012 15.9 5.2 3.0 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR Orf78 PF06024.12 OWF43208.1 - 0.36 11.1 3.1 56 4.1 0.0 3.4 1 1 1 2 2 2 0 Orf78 (ac78) SAPS PF04499.15 OWF43208.1 - 3.1 6.5 11.3 1.8 7.2 2.9 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Ank_2 PF12796.7 OWF43209.1 - 2.2e-30 105.1 10.2 1.2e-08 35.4 0.5 5.1 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF43209.1 - 2.9e-27 94.7 0.3 1.4e-06 28.7 0.1 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF43209.1 - 5.3e-26 90.3 5.9 3.5e-07 30.4 0.1 6.1 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF43209.1 - 6.1e-24 81.5 1.7 0.002 18.4 0.0 8.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OWF43209.1 - 1.9e-23 81.8 3.8 0.00025 21.4 0.2 8.5 8 0 0 8 8 8 5 Ankyrin repeat HEPN_DZIP3 PF18738.1 OWF43209.1 - 2.1e-23 82.7 1.8 7.3e-23 80.9 1.3 2.2 2 0 0 2 2 2 1 DZIP3/ hRUL138-like HEPN DUF5071 PF16804.5 OWF43209.1 - 0.018 15.3 0.0 6.8 7.0 0.0 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) AAA_30 PF13604.6 OWF43209.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zincin_2 PF10103.9 OWF43209.1 - 0.062 12.5 1.0 0.11 11.7 1.0 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF445 PF04286.12 OWF43209.1 - 0.074 12.9 14.2 1.7 8.4 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF445) AAA PF00004.29 OWF43209.1 - 0.076 13.4 1.5 0.72 10.3 0.0 3.3 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.6 OWF43209.1 - 0.13 12.8 2.9 2 9.0 2.5 2.9 1 1 1 2 2 2 0 MCM N-terminal domain RNase_J_C PF17770.1 OWF43209.1 - 0.23 12.5 4.7 0.29 12.2 0.7 3.2 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain AAA_19 PF13245.6 OWF43209.1 - 1.5 9.2 3.9 0.94 9.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain Phasin PF05597.11 OWF43209.1 - 6.6 6.8 7.7 43 4.1 2.2 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HMG_box PF00505.19 OWF43210.1 - 2.8e-24 85.3 3.3 5.3e-24 84.4 3.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF43210.1 - 2e-08 34.7 0.8 4.4e-08 33.6 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain zf-C3HC4_2 PF13923.6 OWF43211.1 - 5.4e-09 35.7 8.2 5.4e-09 35.7 8.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF43211.1 - 3e-08 33.9 6.4 3e-08 33.9 6.4 3.0 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF43211.1 - 6.4e-08 32.3 4.3 6.4e-08 32.3 4.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF43211.1 - 1.2e-07 31.5 7.5 1.2e-07 31.5 7.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF43211.1 - 1.7e-07 31.1 9.7 1.7e-07 31.1 9.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF43211.1 - 1.8e-07 31.0 10.0 5.4e-07 29.5 6.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-TRAF PF02176.18 OWF43211.1 - 7.4e-07 29.8 2.6 8.5e-07 29.6 0.5 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 OWF43211.1 - 3.6e-05 23.8 10.6 4e-05 23.7 7.2 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OWF43211.1 - 0.00068 19.4 5.1 0.00074 19.3 2.6 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 OWF43211.1 - 0.0016 18.6 5.4 0.0016 18.6 5.4 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-TRAF_2 PF15965.5 OWF43211.1 - 0.002 18.5 1.7 0.002 18.5 1.7 2.7 1 1 2 3 3 3 1 TRAF-like zinc-finger zf-RING_10 PF16685.5 OWF43211.1 - 0.0021 18.2 3.8 0.0021 18.2 3.8 2.8 3 1 0 3 3 2 1 zinc RING finger of MSL2 Sina PF03145.16 OWF43211.1 - 0.015 15.3 0.4 0.015 15.3 0.4 1.5 2 0 0 2 2 2 0 Seven in absentia protein family Prok-RING_4 PF14447.6 OWF43211.1 - 0.018 14.9 4.7 0.018 14.9 4.7 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L32p PF01783.23 OWF43211.1 - 0.051 13.8 0.1 0.051 13.8 0.1 2.5 3 0 0 3 3 3 0 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 OWF43211.1 - 0.15 11.5 0.3 0.15 11.5 0.3 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_4 PF14570.6 OWF43211.1 - 0.19 11.5 8.2 3.1 7.7 5.3 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OWF43211.1 - 0.88 9.7 6.8 0.47 10.5 3.6 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-ACC PF17848.1 OWF43211.1 - 1 9.5 3.9 58 3.9 0.0 3.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zinc-ribbons_6 PF07191.12 OWF43211.1 - 1.4 9.0 8.7 5.7 7.0 3.9 2.6 1 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_2 PF13240.6 OWF43211.1 - 1.7 8.4 6.3 4.7 7.1 0.1 3.1 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 OWF43211.1 - 5.3 7.2 10.2 30 4.7 0.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon DUF1272 PF06906.11 OWF43211.1 - 10 6.3 13.1 17 5.6 3.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) Chorein_N PF12624.7 OWF43212.1 - 8.3e-19 67.8 0.0 2.8e-18 66.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Cnn_1N PF07989.11 OWF43212.1 - 2.4 8.4 15.1 1.1 9.4 5.1 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 OWF43212.1 - 8.2 6.7 17.0 6.4 7.1 0.5 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper 7tm_1 PF00001.21 OWF43213.1 - 6.6e-26 91.2 19.2 7.9e-26 90.9 19.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF43213.1 - 4.9e-09 36.2 24.2 1.1e-08 35.0 24.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF43213.1 - 4.8e-05 23.2 18.3 0.00046 20.0 18.3 2.1 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 OWF43214.1 - 1.8e-25 89.8 19.9 2.1e-25 89.5 19.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF43214.1 - 1.1e-10 41.6 20.7 2.3e-10 40.5 20.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF43214.1 - 1.4e-07 31.2 18.0 1.9e-07 30.8 18.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 OWF43214.1 - 1.7e-05 24.7 18.8 3.3e-05 23.7 18.8 1.4 1 1 0 1 1 1 1 Olfactory receptor Saf_2TM PF18303.1 OWF43214.1 - 3.2 7.3 6.4 1.4 8.5 1.6 2.5 1 1 2 3 3 3 0 SAVED-fused 2TM effector domain FA_desaturase PF00487.24 OWF43214.1 - 6.1 6.6 7.0 1.9 8.2 0.2 2.5 1 1 2 3 3 3 0 Fatty acid desaturase 7tm_1 PF00001.21 OWF43215.1 - 6.5e-25 87.9 19.8 7.7e-25 87.7 19.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF43215.1 - 1.9e-09 37.6 24.3 2.6e-09 37.1 23.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF43215.1 - 6.7e-06 26.0 19.9 7.9e-05 22.5 19.9 2.2 1 1 0 1 1 1 1 Olfactory receptor RRM_1 PF00076.22 OWF43216.1 - 1.1e-14 54.0 0.0 1.6e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 OWF43216.1 - 1.8e-05 24.6 4.0 3.4e-05 23.7 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OWF43216.1 - 0.0033 17.2 3.6 0.0057 16.5 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle GRP PF07172.11 OWF43216.1 - 7.5 7.3 19.5 18 6.1 19.5 1.7 1 0 0 1 1 1 0 Glycine rich protein family VHS PF00790.19 OWF43217.1 - 0.04 13.8 1.7 0.13 12.1 0.3 2.8 2 0 0 2 2 2 0 VHS domain TetR_C_20 PF17925.1 OWF43217.1 - 0.098 13.0 3.0 4.9 7.5 0.0 4.1 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain DUF4315 PF14193.6 OWF43217.1 - 0.11 12.5 1.5 0.9 9.6 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) RTP1_C2 PF10304.9 OWF43218.1 - 0.051 13.3 0.9 0.12 12.0 0.9 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 TFIIA PF03153.13 OWF43218.1 - 0.76 9.7 14.6 1.2 9.1 14.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SBF2 PF12335.8 OWF43219.1 - 8.5e-105 349.4 1.3 1.6e-104 348.6 1.3 1.4 1 0 0 1 1 1 1 Myotubularin protein Myotub-related PF06602.14 OWF43219.1 - 1e-86 291.1 0.0 4.4e-86 289.0 0.0 1.9 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain DENN PF02141.21 OWF43219.1 - 1.9e-50 171.4 0.0 6.2e-50 169.7 0.0 2.0 1 0 0 1 1 1 1 DENN (AEX-3) domain GRAM PF02893.20 OWF43219.1 - 2e-17 63.1 0.0 9.8e-17 60.9 0.0 2.2 3 0 0 3 3 3 1 GRAM domain uDENN PF03456.18 OWF43219.1 - 3.4e-17 62.9 0.7 1.1e-16 61.3 0.7 2.0 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.22 OWF43219.1 - 3.1e-14 52.6 7.6 7e-14 51.5 7.6 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 OWF43219.1 - 8.1e-08 32.7 0.0 2.7e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OWF43219.1 - 0.0027 18.0 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain dDENN PF03455.19 OWF43219.1 - 0.0033 17.4 0.0 0.0087 16.0 0.0 1.8 1 0 0 1 1 1 1 dDENN domain PH_11 PF15413.6 OWF43219.1 - 0.0042 17.5 0.2 0.013 16.0 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SPA PF08616.10 OWF43219.1 - 0.011 15.6 0.1 0.043 13.8 0.1 2.0 1 0 0 1 1 1 0 Stabilization of polarity axis PGA2 PF07543.12 OWF43220.1 - 0.18 11.8 1.9 0.32 11.0 1.9 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Acetyltransf_CG PF14542.6 OWF43221.1 - 3.1e-20 72.1 0.0 4.3e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 OWF43221.1 - 0.0086 16.3 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF43221.1 - 0.052 13.5 0.0 0.081 12.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF43221.1 - 0.081 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OWF43221.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Myb_DNA-binding PF00249.31 OWF43222.1 - 2.6e-49 165.2 17.0 3.7e-18 65.4 1.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF43222.1 - 1.1e-38 131.3 13.9 2.3e-18 66.2 0.8 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain Cmyb_C PF09316.10 OWF43222.1 - 5.4e-23 81.5 0.7 5.4e-23 81.5 0.7 2.0 2 0 0 2 2 2 1 C-myb, C-terminal Myb_DNA-bind_7 PF15963.5 OWF43222.1 - 9.7e-13 47.8 6.2 0.00081 19.2 0.1 3.7 1 1 2 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 OWF43222.1 - 0.00033 20.6 1.3 10 6.2 0.0 3.9 2 1 2 4 4 4 2 SLIDE Rap1_C PF11626.8 OWF43222.1 - 0.0024 17.9 5.6 2.1 8.5 0.8 3.5 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OWF43222.1 - 0.011 15.9 6.8 0.95 9.7 0.0 3.8 2 1 2 4 4 4 0 SANT/Myb-like domain of DAMP1 DUF4070 PF13282.6 OWF43222.1 - 0.13 12.4 0.0 0.52 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Myb_DNA-bind_4 PF13837.6 OWF43222.1 - 0.88 10.0 12.6 9.5 6.7 0.6 3.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SET PF00856.28 OWF43223.1 - 4.5e-12 46.7 0.0 1.1e-10 42.2 0.0 2.7 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 OWF43223.1 - 5.6e-10 39.4 3.4 5.9e-06 26.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-MYND PF01753.18 OWF43223.1 - 6.7e-07 29.3 10.5 6.7e-07 29.3 10.5 3.3 3 0 0 3 3 3 1 MYND finger TPR_2 PF07719.17 OWF43223.1 - 1.4e-05 24.9 4.6 0.019 15.1 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF43223.1 - 0.0004 20.1 0.7 0.014 15.1 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF43223.1 - 0.0059 16.7 1.9 3.5 8.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF43223.1 - 0.018 14.7 0.2 0.1 12.3 0.0 2.4 3 0 0 3 3 3 0 TPR repeat RNA_POL_M_15KD PF02150.16 OWF43223.1 - 0.044 13.7 1.7 0.18 11.7 1.7 2.2 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit TPR_14 PF13428.6 OWF43223.1 - 0.05 14.4 0.0 2.4 9.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Got1 PF04178.12 OWF43225.1 - 2.8e-19 69.6 14.4 5.6e-19 68.6 14.4 1.5 1 0 0 1 1 1 1 Got1/Sft2-like family Fzo_mitofusin PF04799.13 OWF43225.1 - 0.17 11.4 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region QCR10 PF09796.9 OWF43225.1 - 1.8 8.7 7.6 0.9 9.6 1.0 2.7 2 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Lectin_C PF00059.21 OWF43226.1 - 0.011 16.5 2.9 0.061 14.1 2.9 1.9 1 1 0 1 1 1 0 Lectin C-type domain Flu_B_M2 PF04772.12 OWF43226.1 - 0.14 12.4 0.2 17 5.7 0.1 2.2 2 0 0 2 2 2 0 Influenza B matrix protein 2 (BM2) Phage_TAC_7 PF10109.9 OWF43226.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 Glyco_transf_54 PF04666.13 OWF43227.1 - 4.7e-77 258.7 8.9 7.2e-77 258.1 8.9 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF2207 PF09972.9 OWF43228.1 - 0.02 13.7 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CD225 PF04505.12 OWF43228.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein APG9 PF04109.16 OWF43228.1 - 0.088 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 DUF5383 PF17355.2 OWF43228.1 - 0.11 12.9 0.2 11 6.4 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Glyco_hydro_18 PF00704.28 OWF43230.1 - 2.2e-08 34.2 0.6 3.7e-08 33.5 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 TSC21 PF15217.6 OWF43231.1 - 0.018 15.0 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 TSC21 family zf-C2H2_4 PF13894.6 OWF43233.1 - 3.3e-08 33.7 30.5 0.027 15.3 2.9 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43233.1 - 2.6e-07 30.7 34.8 0.0027 18.1 3.4 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type C1_4 PF07975.12 OWF43233.1 - 6.9e-05 23.0 9.7 0.39 11.0 3.0 3.4 3 0 0 3 3 3 2 TFIIH C1-like domain HNH PF01844.23 OWF43233.1 - 0.014 15.6 16.4 0.14 12.3 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease Zn-ribbon_8 PF09723.10 OWF43233.1 - 0.02 15.0 10.4 1.1 9.5 1.3 3.5 3 0 0 3 3 3 0 Zinc ribbon domain HypA PF01155.19 OWF43233.1 - 0.027 14.5 6.4 0.029 14.4 2.7 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_2 PF13465.6 OWF43233.1 - 0.041 14.3 1.1 0.041 14.3 1.1 5.5 6 0 0 6 6 5 0 Zinc-finger double domain zf-C2HE PF16278.5 OWF43233.1 - 0.09 13.2 16.3 1.1 9.7 0.4 4.3 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF629 PF04780.12 OWF43233.1 - 0.13 10.7 12.5 2 6.9 3.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_3rep PF18868.1 OWF43233.1 - 0.21 12.3 13.4 1.3 9.7 1.0 3.8 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OWF43233.1 - 1.6 9.1 21.3 8 6.9 1.9 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 OWF43233.1 - 1.9 8.6 11.3 5.7 7.0 0.1 3.7 2 1 1 3 3 3 0 CpXC protein zf-MYST PF17772.1 OWF43233.1 - 2.7 7.7 8.6 0.64 9.7 0.5 2.7 3 0 0 3 3 3 0 MYST family zinc finger domain LIM PF00412.22 OWF43233.1 - 3.7 7.8 15.2 1.3 9.3 3.5 3.3 3 0 0 3 3 3 0 LIM domain zinc_ribbon_15 PF17032.5 OWF43233.1 - 3.8 8.3 16.0 0.41 11.4 4.3 3.0 1 1 1 3 3 3 0 zinc-ribbon family zf-LYAR PF08790.11 OWF43233.1 - 5.9 6.9 14.7 2.4 8.1 1.0 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 OWF43233.1 - 7.7 6.7 12.6 11 6.3 0.2 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) p53-inducible11 PF14936.6 OWF43234.1 - 1.5e-53 181.6 0.7 1.8e-53 181.3 0.7 1.0 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF4345 PF14248.6 OWF43234.1 - 0.012 15.5 0.9 0.012 15.5 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) PADR1 PF08063.12 OWF43235.1 - 5.2e-06 26.2 61.1 18 5.2 0.4 20.7 2 1 17 19 19 19 15 PADR1 (NUC008) domain FAM198 PF15051.6 OWF43236.1 - 1.8e-05 23.8 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FAM198 protein Myc_N PF01056.18 OWF43236.1 - 0.41 10.5 5.9 0.63 9.9 5.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Astro_capsid_p PF12226.8 OWF43236.1 - 3.9 6.5 9.1 6.2 5.9 9.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Mab-21 PF03281.14 OWF43237.1 - 7.7e-30 104.2 0.6 1.6e-29 103.1 0.6 1.5 1 0 0 1 1 1 1 Mab-21 protein TPR_1 PF00515.28 OWF43237.1 - 0.0016 18.2 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF43237.1 - 0.049 13.9 0.2 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OWF43237.1 - 0.071 13.3 0.1 4.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF43237.1 - 0.19 11.9 0.3 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_7 PF03492.15 OWF43238.1 - 8.1e-10 38.4 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase YwpF PF14183.6 OWF43239.1 - 0.031 14.3 0.0 0.061 13.3 0.0 1.5 1 1 0 1 1 1 0 YwpF-like protein Methyltransf_7 PF03492.15 OWF43239.1 - 0.055 12.7 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase 7tm_1 PF00001.21 OWF43241.1 - 1.6e-18 67.0 8.2 1.9e-18 66.7 8.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cation_ATPase_C PF00689.21 OWF43241.1 - 0.0031 17.3 1.9 0.75 9.5 0.4 2.4 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus EVI2A PF05399.11 OWF43241.1 - 0.0038 16.9 0.3 0.0066 16.1 0.3 1.3 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF3084 PF11283.8 OWF43241.1 - 0.0099 15.8 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3084) CCB1 PF12046.8 OWF43241.1 - 0.041 13.2 1.4 0.18 11.1 0.4 2.4 2 1 0 2 2 2 0 Cofactor assembly of complex C subunit B DUF3641 PF12345.8 OWF43242.1 - 5.7e-50 168.9 0.5 1.1e-49 168.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) Fer4_12 PF13353.6 OWF43242.1 - 0.00014 22.2 0.1 0.00031 21.0 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 OWF43242.1 - 0.00022 21.6 0.0 0.00053 20.4 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily LIM PF00412.22 OWF43243.1 - 1.1e-22 80.0 22.3 2e-12 47.1 5.8 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 OWF43243.1 - 9.1e-05 22.0 19.0 0.52 9.9 0.1 4.8 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OWF43243.1 - 0.0014 18.7 21.8 0.87 9.8 0.3 4.2 4 0 0 4 4 4 3 Zinc ribbon domain zf-RRN7 PF11781.8 OWF43243.1 - 0.0059 16.3 0.5 0.0059 16.3 0.5 4.2 4 1 0 4 4 3 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 OWF43243.1 - 0.02 14.9 23.3 3.5 7.7 7.8 4.2 2 2 0 2 2 2 0 Double zinc ribbon zf-ACC PF17848.1 OWF43243.1 - 0.079 13.0 0.5 0.079 13.0 0.5 4.7 6 0 0 6 6 6 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_2 PF13240.6 OWF43243.1 - 0.24 11.2 0.4 0.24 11.2 0.4 5.9 6 0 0 6 6 6 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 OWF43243.1 - 0.94 9.5 18.0 8.4 6.4 0.1 4.7 4 2 0 4 4 4 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 OWF43243.1 - 1.2 9.1 8.0 2.7 8.0 0.5 2.6 2 1 0 2 2 2 0 Cysteine-rich CPXCG MqsA_antitoxin PF15731.5 OWF43243.1 - 1.2 9.3 8.0 1.7 8.7 0.3 2.9 2 2 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Zn_Tnp_IS1595 PF12760.7 OWF43243.1 - 1.3 9.0 28.1 3.8 7.6 1.2 4.0 2 2 2 4 4 4 0 Transposase zinc-ribbon domain DUF2688 PF10892.8 OWF43243.1 - 3.2 7.3 12.8 5 6.7 0.6 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) YacG PF03884.14 OWF43243.1 - 4.9 7.0 12.7 11 5.9 2.4 3.5 3 1 0 3 3 3 0 DNA gyrase inhibitor YacG zf-Mss51 PF13824.6 OWF43243.1 - 4.9 7.3 16.5 0.31 11.2 1.7 3.1 2 2 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Sgf11 PF08209.11 OWF43243.1 - 6.3 6.4 21.4 11 5.7 0.1 5.2 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Aminotran_4 PF01063.19 OWF43244.1 - 1.1e-27 97.3 0.0 1.4e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DNA_methylase PF00145.17 OWF43245.1 - 7.8e-30 104.4 0.0 5.5e-27 95.0 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase MTS PF05175.14 OWF43245.1 - 0.067 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ras PF00071.22 OWF43246.1 - 1.1e-53 181.1 1.6 2.6e-53 179.9 1.6 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43246.1 - 1.8e-33 115.3 1.0 4.1e-33 114.1 1.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43246.1 - 1.7e-16 60.1 0.2 1.7e-16 60.1 0.2 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family EF-hand_7 PF13499.6 OWF43246.1 - 5.6e-09 36.3 1.2 5.6e-09 36.3 1.2 3.8 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF43246.1 - 1.5e-08 33.6 3.0 0.00027 20.3 0.4 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF43246.1 - 3.7e-08 32.6 2.8 0.00052 19.7 0.4 3.8 3 0 0 3 3 3 2 EF-hand domain MMR_HSR1 PF01926.23 OWF43246.1 - 1.2e-07 31.8 0.2 1.2e-07 31.8 0.2 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 OWF43246.1 - 8.9e-05 22.3 2.9 0.00019 21.2 0.9 2.6 2 1 1 3 3 3 1 EF-hand domain pair GTP_EFTU PF00009.27 OWF43246.1 - 0.00025 20.7 0.6 0.00025 20.7 0.6 3.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF43246.1 - 0.0026 17.7 5.6 0.004 17.1 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase EF-hand_5 PF13202.6 OWF43246.1 - 0.021 14.3 1.5 0.021 14.3 1.5 2.7 3 0 0 3 3 3 0 EF hand AAA_7 PF12775.7 OWF43246.1 - 0.028 14.0 0.1 0.065 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region EF-hand_4 PF12763.7 OWF43246.1 - 0.057 13.4 0.4 0.057 13.4 0.4 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand AAA PF00004.29 OWF43246.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.6 3 1 1 4 4 3 0 ATPase family associated with various cellular activities (AAA) Glyco_transf_34 PF05637.12 OWF43246.1 - 0.28 10.9 6.4 0.083 12.6 2.9 1.9 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family MCR_beta_N PF02783.15 OWF43246.1 - 0.41 10.2 4.9 2 8.0 0.3 2.4 2 0 0 2 2 2 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain AAA_16 PF13191.6 OWF43246.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.0 2 1 0 2 2 1 0 AAA ATPase domain DUF2283 PF10049.9 OWF43246.1 - 4 7.7 8.1 48 4.3 4.5 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Glutaredoxin PF00462.24 OWF43247.1 - 1.8e-14 53.7 1.0 2.7e-14 53.1 0.2 1.7 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 OWF43247.1 - 7.3e-05 22.7 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 OWF43247.1 - 0.0013 19.1 1.1 0.0015 18.9 0.4 1.6 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 OWF43247.1 - 0.0029 17.4 0.4 0.14 11.9 0.3 2.2 2 0 0 2 2 2 1 DSBA-like thioredoxin domain TraF PF13728.6 OWF43247.1 - 0.0068 16.3 0.2 0.015 15.1 0.2 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 OWF43247.1 - 0.1 13.1 0.7 0.15 12.6 0.7 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Ysc84 PF04366.12 OWF43249.1 - 5.8e-43 145.7 0.0 1.2e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 OWF43249.1 - 3.5e-11 42.5 0.0 1.2e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF43249.1 - 7.2e-09 35.2 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OWF43249.1 - 1.1e-08 34.8 0.0 2.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain 2OG-FeII_Oxy_3 PF13640.6 OWF43250.1 - 3.9e-13 50.1 0.1 1.2e-12 48.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OWF43250.1 - 0.00043 20.7 0.0 0.0015 19.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 OWF43250.1 - 0.00097 19.1 0.3 0.0042 17.1 0.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF43250.1 - 0.005 17.5 0.1 0.015 15.9 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat 2OG-FeII_Oxy_4 PF13661.6 OWF43250.1 - 0.0061 17.2 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OWF43250.1 - 0.0089 16.4 0.0 0.044 14.2 0.0 2.1 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase TPR_7 PF13176.6 OWF43250.1 - 0.057 13.5 0.2 2.3 8.4 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 OWF43251.1 - 8.2e-06 26.2 0.1 0.00017 22.0 0.0 2.9 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OWF43251.1 - 0.13 12.7 0.0 5.3 7.5 0.0 3.0 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase TPR_2 PF07719.17 OWF43251.1 - 0.24 11.6 11.9 0.12 12.6 1.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 OWF43252.1 - 8.1e-15 55.0 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF43252.1 - 1.9e-10 41.9 0.0 3.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.20 OWF43252.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.21 OWF43252.1 - 0.024 14.0 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 ThiF family UPF0160 PF03690.13 OWF43253.1 - 3.2e-142 473.9 0.1 3e-141 470.7 0.0 2.4 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0160) PI-PLC-X PF00388.19 OWF43253.1 - 1.7e-61 206.0 0.0 9.5e-61 203.6 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OWF43253.1 - 2e-31 108.7 0.2 5.8e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OWF43253.1 - 7.2e-18 64.8 0.1 2e-15 57.0 0.0 2.6 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 OWF43253.1 - 1.1e-16 61.0 3.2 1.3e-16 60.9 0.6 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 OWF43253.1 - 1e-09 38.7 5.1 5.2e-08 33.2 1.2 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_10 PF14788.6 OWF43253.1 - 1e-09 38.1 2.1 1.9e-09 37.2 0.8 2.2 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 OWF43253.1 - 4.2e-08 32.5 6.9 0.00013 21.6 0.4 4.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 OWF43253.1 - 3.2e-07 29.4 6.3 8.3e-06 25.0 0.2 4.4 4 0 0 4 4 4 1 EF hand PH PF00169.29 OWF43253.1 - 8.5e-06 26.2 0.0 2.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_5 PF13202.6 OWF43253.1 - 1.6e-05 24.2 1.3 0.00024 20.4 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF43253.1 - 0.021 14.7 3.1 0.39 10.6 0.3 3.2 2 1 1 3 3 3 0 EF-hand domain pair DUF2849 PF11011.8 OWF43253.1 - 0.16 12.6 0.1 0.51 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) DUF3386 PF11866.8 OWF43253.1 - 0.27 10.7 4.4 0.13 11.7 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3386) WD40 PF00400.32 OWF43254.1 - 5.5e-05 23.8 10.0 0.038 14.9 1.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat PTCB-BRCT PF12738.7 OWF43255.1 - 7.3e-53 176.4 0.5 1.2e-22 79.6 0.1 6.0 6 0 0 6 6 6 5 twin BRCT domain BRCT PF00533.26 OWF43255.1 - 2.8e-42 143.0 0.0 1.7e-12 47.6 0.0 6.3 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OWF43255.1 - 1.1e-36 125.0 0.0 1.3e-05 25.5 0.0 6.2 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OWF43255.1 - 3.5e-18 65.3 0.0 6.9e-13 48.3 0.0 4.0 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 OWF43255.1 - 2.5e-09 37.3 4.2 0.0056 16.9 0.1 5.3 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OWF43255.1 - 1.5e-05 24.9 1.2 0.075 13.1 0.0 4.4 4 1 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Glyco_hydro_32C PF08244.12 OWF43257.1 - 0.18 11.8 7.8 3.4 7.6 0.2 3.3 2 2 0 3 3 3 0 Glycosyl hydrolases family 32 C terminal Big_3_4 PF13754.6 OWF43257.1 - 0.65 9.8 21.6 3.8 7.3 1.6 4.2 1 1 3 4 4 4 0 Domain of unknown function EF-hand_13 PF17958.1 OWF43257.1 - 0.65 9.8 36.3 0.22 11.4 0.7 7.7 1 1 9 10 10 10 0 EF-hand domain DUF3023 PF11224.8 OWF43257.1 - 2.4 8.0 18.5 2.4 8.0 6.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3023) PRRSV_2b PF07069.11 OWF43257.1 - 8.3 7.0 10.7 19 5.8 1.8 3.0 2 1 1 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b NinF PF05810.12 OWF43257.1 - 8.7 6.3 22.3 42 4.1 0.5 7.6 2 2 6 8 8 8 0 NinF protein F5_F8_type_C PF00754.25 OWF43258.1 - 2.9e-50 169.7 10.7 3.4e-25 88.6 0.8 4.2 4 1 0 4 4 4 3 F5/8 type C domain Glu-tRNAGln PF02686.15 OWF43260.1 - 1.6e-06 28.3 7.1 14 6.1 0.1 8.0 4 4 2 6 6 6 1 Glu-tRNAGln amidotransferase C subunit Adhes-Ig_like PF09085.10 OWF43260.1 - 4.7e-05 23.5 0.5 15 5.8 0.0 6.8 6 3 1 8 8 8 1 Adhesion molecule, immunoglobulin-like BLOC1_2 PF10046.9 OWF43260.1 - 0.00024 21.3 2.5 19 5.6 0.1 6.3 5 2 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG17 PF04108.12 OWF43260.1 - 0.0005 19.3 29.4 0.11 11.6 1.3 5.9 2 2 3 6 6 6 4 Autophagy protein Apg17 Bep_C_terminal PF17841.1 OWF43260.1 - 0.00056 20.1 3.8 30 4.9 0.0 6.3 5 2 2 7 7 7 0 BID domain of Bartonella effector protein (Bep) Use1 PF09753.9 OWF43260.1 - 0.0018 18.1 18.8 8.7 6.0 0.1 7.8 6 3 1 8 8 8 1 Membrane fusion protein Use1 V-set_2 PF15910.5 OWF43260.1 - 0.0084 16.2 9.7 22 5.2 0.3 5.5 2 1 2 5 5 5 0 ICOS V-set domain Ribosomal_L34e PF01199.18 OWF43260.1 - 0.024 14.9 15.2 10 6.5 0.3 8.1 5 3 5 10 10 10 0 Ribosomal protein L34e YkyA PF10368.9 OWF43260.1 - 0.029 14.0 0.0 24 4.5 0.0 4.2 4 0 0 4 4 4 0 Putative cell-wall binding lipoprotein LAP2alpha PF11560.8 OWF43260.1 - 0.031 13.7 3.0 94 2.3 0.1 5.3 2 2 4 6 6 6 0 Lamina-associated polypeptide 2 alpha DUF948 PF06103.11 OWF43260.1 - 5.8 7.3 18.2 33 4.8 0.1 6.8 3 2 4 7 7 7 0 Bacterial protein of unknown function (DUF948) AsnA PF03590.15 OWF43260.1 - 7.3 6.3 34.2 0.84 9.3 1.6 6.5 1 1 3 6 6 6 0 Aspartate-ammonia ligase Thyroglobulin_1 PF00086.18 OWF43261.1 - 2.9e-08 33.3 2.7 7.8e-08 31.9 2.7 1.7 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat YL1 PF05764.13 OWF43261.1 - 0.0011 19.2 18.4 0.0011 19.2 18.4 5.9 2 1 2 5 5 5 1 YL1 nuclear protein OGFr_N PF04664.13 OWF43262.1 - 1.1e-70 237.3 1.7 1.6e-70 236.9 1.7 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region ABC_membrane PF00664.23 OWF43263.1 - 3.8e-54 184.2 4.7 5.2e-54 183.7 4.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OWF43263.1 - 4.5e-31 108.2 0.0 9.6e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF43263.1 - 1.5e-05 24.5 0.0 0.00034 20.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OWF43263.1 - 0.0085 16.4 0.0 0.036 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 OWF43263.1 - 0.014 15.3 0.3 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_membrane_2 PF06472.15 OWF43263.1 - 0.024 14.1 1.2 0.042 13.3 1.2 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 Zeta_toxin PF06414.12 OWF43263.1 - 0.036 13.4 0.2 0.34 10.2 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 OWF43263.1 - 0.16 11.5 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OWF43263.1 - 0.19 12.0 0.5 1.6 9.0 0.4 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Tnp_zf-ribbon_2 PF13842.6 OWF43264.1 - 0.1 13.4 5.3 0.15 12.9 5.3 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon C6_DPF PF10170.9 OWF43264.1 - 0.13 12.6 1.0 0.13 12.6 1.0 2.0 1 1 1 2 2 2 0 Cysteine-rich domain zf-B_box PF00643.24 OWF43264.1 - 4.2 7.6 7.9 12 6.2 7.9 1.7 1 1 0 1 1 1 0 B-box zinc finger zf-H2C2_2 PF13465.6 OWF43264.1 - 4.6 7.8 10.6 19 5.9 0.2 3.3 2 1 1 3 3 3 0 Zinc-finger double domain Tnp_zf-ribbon_2 PF13842.6 OWF43265.1 - 0.029 15.2 5.5 0.066 14.0 5.5 1.7 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon FlhC PF05280.11 OWF43265.1 - 0.2 11.3 4.5 0.29 10.9 4.5 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Tnp_zf-ribbon_2 PF13842.6 OWF43266.1 - 0.035 14.9 8.0 0.035 14.9 8.0 1.9 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2 PF00096.26 OWF43267.1 - 8.6e-09 35.4 20.3 0.00013 22.2 1.4 3.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43267.1 - 5.3e-08 33.0 16.7 0.0044 17.8 0.6 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OWF43267.1 - 0.00046 20.2 14.1 0.0052 16.9 1.4 3.6 3 1 0 3 3 3 1 Zinc ribbon domain zf-C2H2_jaz PF12171.8 OWF43267.1 - 0.00048 20.3 1.4 0.00048 20.3 1.4 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF43267.1 - 0.0019 18.5 2.3 0.0019 18.5 2.3 3.6 4 0 0 4 4 3 2 Zinc-finger double domain zf-met PF12874.7 OWF43267.1 - 0.0072 16.7 12.3 0.34 11.3 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-MYST PF17772.1 OWF43267.1 - 0.015 14.9 0.4 0.015 14.9 0.4 3.1 2 1 1 3 3 3 0 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 OWF43267.1 - 0.024 14.3 3.8 0.066 12.9 3.6 1.8 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 OWF43267.1 - 0.028 14.4 2.2 0.028 14.4 2.2 3.6 4 0 0 4 4 3 0 C2H2-type zinc finger zf-3CxxC_2 PF17180.4 OWF43267.1 - 0.029 15.1 1.6 0.029 15.1 1.6 2.7 2 1 1 3 3 2 0 Zinc-binding domain zf-C2H2_11 PF16622.5 OWF43267.1 - 0.04 13.7 1.9 0.04 13.7 1.9 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type HypA PF01155.19 OWF43267.1 - 0.1 12.7 10.0 0.06 13.4 7.2 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC_2 PF13913.6 OWF43267.1 - 0.46 10.4 12.7 5.9 6.9 0.1 3.8 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 OWF43267.1 - 0.51 10.0 12.1 0.96 9.1 1.6 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 OWF43267.1 - 2.9 8.2 14.4 0.39 11.0 6.4 2.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.6 OWF43267.1 - 4.6 7.3 11.4 0.12 12.5 1.3 2.6 1 1 2 3 3 3 0 CpXC protein LIM PF00412.22 OWF43267.1 - 8.8 6.6 16.7 25 5.2 6.8 3.1 1 1 1 2 2 2 0 LIM domain zf-H2C2_2 PF13465.6 OWF43268.1 - 2.1e-08 34.2 12.4 0.00017 21.8 1.3 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 OWF43268.1 - 4.8e-07 29.9 12.0 0.0044 17.4 1.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43268.1 - 9.8e-07 29.1 11.3 0.0021 18.8 3.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger CpXC PF14353.6 OWF43268.1 - 0.0026 17.8 4.7 0.0081 16.2 0.4 2.1 1 1 1 2 2 2 1 CpXC protein zf-CHCC PF10276.9 OWF43268.1 - 0.0081 16.2 1.4 3.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger domain zf-C2H2_6 PF13912.6 OWF43268.1 - 0.047 13.7 12.5 0.32 11.0 2.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-AN1 PF01428.16 OWF43268.1 - 0.067 13.4 5.8 0.97 9.6 1.4 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger YyzF PF14116.6 OWF43268.1 - 0.19 11.8 2.1 4.7 7.3 0.2 2.4 2 0 0 2 2 2 0 YyzF-like protein zf-C2HE PF16278.5 OWF43268.1 - 0.2 12.1 5.6 2.7 8.5 5.6 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 OWF43268.1 - 0.29 11.3 7.0 2.3 8.4 7.0 2.1 1 1 0 1 1 1 0 FYVE zinc finger Ephrin_rec_like PF07699.13 OWF43268.1 - 1.2 9.0 10.7 0.79 9.5 2.2 2.6 2 1 1 3 3 3 0 Putative ephrin-receptor like zf-Di19 PF05605.12 OWF43268.1 - 1.3 9.4 8.0 0.41 11.0 1.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.12 OWF43268.1 - 1.6 7.1 8.0 1.8 7.0 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.6 OWF43268.1 - 9.9 6.2 10.9 0.75 9.8 0.3 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 OWF43269.1 - 7.3e-09 35.6 22.6 0.0024 18.2 0.7 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43269.1 - 9.8e-09 35.3 22.5 0.0064 17.2 1.9 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43269.1 - 2.3e-07 30.9 18.8 0.047 14.1 0.7 4.1 4 0 0 4 4 4 3 Zinc-finger double domain Ephrin_rec_like PF07699.13 OWF43269.1 - 0.0013 18.5 5.2 0.55 10.0 0.4 3.1 3 0 0 3 3 3 2 Putative ephrin-receptor like CpXC PF14353.6 OWF43269.1 - 0.0014 18.6 7.9 0.039 14.0 0.1 2.9 1 1 2 3 3 3 1 CpXC protein zinc_ribbon_10 PF10058.9 OWF43269.1 - 0.016 14.9 1.6 4.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_9 PF14369.6 OWF43269.1 - 0.02 15.2 9.5 4 7.8 0.5 3.2 2 1 1 3 3 3 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 OWF43269.1 - 0.054 13.0 0.7 1 8.9 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2HC_2 PF13913.6 OWF43269.1 - 0.089 12.7 1.0 0.089 12.7 1.0 3.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type SPACA9 PF15120.6 OWF43269.1 - 0.093 12.5 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 zf_UBZ PF18439.1 OWF43269.1 - 0.12 12.0 5.4 0.58 9.8 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 OWF43269.1 - 0.18 12.6 7.4 0.097 13.4 2.3 2.1 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 OWF43269.1 - 0.29 11.5 17.3 2.2 8.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 OWF43269.1 - 0.53 10.3 11.2 5.9 6.9 0.3 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif HypA PF01155.19 OWF43269.1 - 0.58 10.2 6.4 2.3 8.2 4.4 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HNH_5 PF14279.6 OWF43269.1 - 0.73 9.7 6.9 8.6 6.3 0.7 3.1 3 0 0 3 3 3 0 HNH endonuclease Med27 PF11571.8 OWF43269.1 - 1 9.8 11.3 1.9 8.9 5.5 2.8 1 1 1 2 2 2 0 Mediator complex subunit 27 LIM PF00412.22 OWF43269.1 - 1 9.7 12.5 32 4.8 6.1 2.5 1 1 1 2 2 2 0 LIM domain zf_C2H2_ZHX PF18387.1 OWF43269.1 - 1.4 8.6 9.9 0.048 13.3 2.7 2.2 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2256 PF10013.9 OWF43269.1 - 2 8.6 10.1 17 5.6 0.6 3.4 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Laminin_EGF PF00053.24 OWF43269.1 - 2.8 8.1 9.6 8.6 6.6 0.6 3.1 2 1 1 3 3 3 0 Laminin EGF domain zf-MYST PF17772.1 OWF43269.1 - 3 7.5 10.8 2.8 7.6 2.6 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain DUF629 PF04780.12 OWF43269.1 - 3.4 6.1 12.6 0.63 8.5 0.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Zn_Tnp_IS1595 PF12760.7 OWF43269.1 - 3.5 7.7 12.5 4.4 7.4 7.4 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Chordopox_RPO7 PF05864.12 OWF43269.1 - 7.4 6.9 5.9 24 5.3 0.1 2.7 2 1 1 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-LYAR PF08790.11 OWF43269.1 - 8.4 6.4 15.3 4.7 7.2 1.1 3.6 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 OWF43270.1 - 6.7e-10 38.9 20.3 0.00032 21.0 3.0 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43270.1 - 5.9e-09 36.0 20.8 0.0021 18.7 1.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43270.1 - 2.7e-08 33.9 17.5 0.001 19.4 0.7 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 OWF43270.1 - 0.00091 19.5 9.0 1.2 9.6 0.2 3.1 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OWF43270.1 - 0.0016 18.4 22.2 0.0096 15.9 1.9 3.8 3 1 0 3 3 3 1 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 OWF43270.1 - 0.0027 17.6 2.4 0.0027 17.6 2.4 2.3 1 1 1 2 2 2 1 SprT-like zinc ribbon domain Ephrin_rec_like PF07699.13 OWF43270.1 - 0.0029 17.3 8.6 0.94 9.3 1.7 3.2 3 0 0 3 3 3 2 Putative ephrin-receptor like DUF2256 PF10013.9 OWF43270.1 - 0.0034 17.5 5.0 2.6 8.2 0.0 3.3 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_jaz PF12171.8 OWF43270.1 - 0.0037 17.5 15.1 0.1 12.9 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 OWF43270.1 - 0.005 16.9 13.7 0.35 11.0 0.1 3.2 2 1 1 3 3 3 1 Zinc ribbon domain zf_UBZ PF18439.1 OWF43270.1 - 0.005 16.4 5.2 1.5 8.5 0.1 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 OWF43270.1 - 0.0069 16.0 5.4 0.0074 15.9 0.7 2.3 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_9 PF14369.6 OWF43270.1 - 0.0099 16.1 3.0 14 6.1 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon CpXC PF14353.6 OWF43270.1 - 0.015 15.3 6.5 0.069 13.2 0.2 2.4 1 1 1 2 2 2 0 CpXC protein HNH_5 PF14279.6 OWF43270.1 - 0.02 14.7 2.5 2.6 8.0 0.5 3.0 2 1 0 2 2 2 0 HNH endonuclease zf-met PF12874.7 OWF43270.1 - 0.026 14.9 0.1 0.026 14.9 0.1 3.5 4 0 0 4 4 3 0 Zinc-finger of C2H2 type XPA_N PF01286.18 OWF43270.1 - 0.11 12.5 6.8 2.5 8.2 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zinc_ribbon_15 PF17032.5 OWF43270.1 - 0.14 12.9 6.8 2.2 9.1 7.4 2.2 1 1 1 2 2 2 0 zinc-ribbon family C1_1 PF00130.22 OWF43270.1 - 0.18 11.7 9.0 0.59 10.1 2.3 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.6 OWF43270.1 - 0.24 11.3 7.5 1.6 8.6 0.1 3.2 3 1 0 3 3 3 0 Probable zinc-ribbon domain FYDLN_acid PF09538.10 OWF43270.1 - 0.26 12.0 3.5 2.2 9.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.16 OWF43270.1 - 0.3 11.3 8.7 2.3 8.4 1.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger zf-MYST PF17772.1 OWF43270.1 - 0.32 10.6 9.6 1.2 8.8 2.6 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain HypA PF01155.19 OWF43270.1 - 0.36 10.9 4.9 0.21 11.6 1.1 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LYAR PF08790.11 OWF43270.1 - 0.4 10.6 15.2 1.6 8.7 0.4 3.5 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger LIM PF00412.22 OWF43270.1 - 0.54 10.5 11.9 1.1 9.5 5.9 2.5 1 1 1 2 2 2 0 LIM domain TFIIS_C PF01096.18 OWF43270.1 - 0.72 9.8 6.9 2.6 7.9 0.2 2.9 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) DZR PF12773.7 OWF43270.1 - 0.73 9.9 6.1 5.1 7.2 2.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-C2HC_2 PF13913.6 OWF43270.1 - 0.95 9.4 12.6 0.32 10.9 1.3 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-HIT PF04438.16 OWF43270.1 - 1.2 9.0 9.3 7.4 6.5 0.2 3.4 3 0 0 3 3 3 0 HIT zinc finger Cytochrome_C7 PF14522.6 OWF43270.1 - 1.3 9.0 10.1 0.51 10.4 5.6 2.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c DUF629 PF04780.12 OWF43270.1 - 2 6.9 9.6 2.8 6.3 3.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Laminin_EGF PF00053.24 OWF43270.1 - 2.7 8.2 7.6 5.6 7.2 0.4 2.8 3 0 0 3 3 3 0 Laminin EGF domain zf-UBP PF02148.19 OWF43270.1 - 8.2 6.8 12.3 3.9 7.9 0.4 2.7 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_4 PF13894.6 OWF43271.1 - 5.1e-12 45.6 18.7 0.002 18.8 2.7 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43271.1 - 1.3e-11 44.3 19.5 0.001 19.4 4.9 3.5 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF43271.1 - 1.4e-07 31.6 14.7 0.0031 17.8 2.1 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 OWF43271.1 - 0.00022 21.3 3.8 0.02 15.0 0.6 2.6 2 1 0 2 2 2 1 Zinc ribbon domain Rpr2 PF04032.16 OWF43271.1 - 0.00056 20.1 1.9 0.28 11.5 0.3 2.2 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-met PF12874.7 OWF43271.1 - 0.0016 18.7 10.3 0.46 11.0 0.9 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF43271.1 - 0.0022 17.9 19.4 0.054 13.5 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 OWF43271.1 - 0.0041 17.4 8.5 0.052 13.9 4.4 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 OWF43271.1 - 0.0044 17.4 2.3 0.0044 17.4 2.3 4.2 4 2 0 4 4 3 1 Zinc-finger double domain Nudix_N_2 PF14803.6 OWF43271.1 - 0.0059 16.5 2.8 2.4 8.2 0.0 3.2 3 0 0 3 3 3 1 Nudix N-terminal zf_C2H2_ZHX PF18387.1 OWF43271.1 - 0.0073 15.9 1.6 0.0073 15.9 1.6 1.8 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 OWF43271.1 - 0.0092 15.7 13.3 0.62 9.9 1.8 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type DUF2180 PF09947.9 OWF43271.1 - 0.016 15.2 4.1 2.2 8.3 0.1 2.6 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Cript PF10235.9 OWF43271.1 - 0.047 14.3 7.6 0.14 12.7 1.9 2.3 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zf-C2H2_2 PF12756.7 OWF43271.1 - 0.061 13.7 10.6 2 8.8 0.5 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 OWF43271.1 - 0.072 13.1 4.5 1.3 9.1 0.0 2.9 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-HIT PF04438.16 OWF43271.1 - 0.12 12.2 0.3 0.12 12.2 0.3 3.4 4 0 0 4 4 3 0 HIT zinc finger zinc_ribbon_15 PF17032.5 OWF43271.1 - 0.14 12.9 6.0 1.4 9.8 6.2 2.2 1 1 0 1 1 1 0 zinc-ribbon family XPA_N PF01286.18 OWF43271.1 - 0.15 12.1 0.2 0.15 12.1 0.2 3.2 4 0 0 4 4 3 0 XPA protein N-terminal LIM PF00412.22 OWF43271.1 - 0.18 12.0 10.7 3.9 7.8 8.8 2.9 1 1 1 2 2 2 0 LIM domain CpXC PF14353.6 OWF43271.1 - 0.25 11.4 6.5 1.2 9.2 2.0 2.8 1 1 1 2 2 2 0 CpXC protein zf-C2H2_3rep PF18868.1 OWF43271.1 - 0.26 12.0 5.9 5 7.8 0.2 2.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 OWF43271.1 - 0.42 10.8 9.3 1.9 8.7 0.3 3.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 OWF43271.1 - 0.42 10.2 8.5 1.4 8.6 0.1 3.3 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger Sprouty PF05210.13 OWF43271.1 - 0.53 10.7 5.2 0.86 10.0 2.0 2.0 2 0 0 2 2 2 0 Sprouty protein (Spry) HNH_5 PF14279.6 OWF43271.1 - 0.54 10.1 6.8 1.3 9.0 0.2 3.0 3 0 0 3 3 3 0 HNH endonuclease HypA PF01155.19 OWF43271.1 - 0.7 9.9 5.7 0.68 10.0 1.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 OWF43271.1 - 0.7 9.8 13.7 3.1 7.7 1.6 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 OWF43271.1 - 0.8 9.7 7.2 11 6.0 7.3 2.4 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_8 PF15909.5 OWF43271.1 - 0.93 9.8 7.4 0.14 12.4 2.3 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon HNH PF01844.23 OWF43271.1 - 1 9.6 7.5 19 5.5 0.1 3.2 3 0 0 3 3 3 0 HNH endonuclease zf-3CxxC PF13695.6 OWF43271.1 - 1.1 9.8 7.9 3.3 8.3 3.4 2.6 1 1 1 2 2 2 0 Zinc-binding domain MTHFR_C PF12225.8 OWF43271.1 - 1.1 8.9 6.8 9.3 6.0 0.1 2.8 1 1 2 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal DUF2321 PF10083.9 OWF43271.1 - 1.6 8.4 6.0 2.6 7.6 3.3 2.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn_ribbon_recom PF13408.6 OWF43271.1 - 2.4 8.7 11.7 0.64 10.6 3.9 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain C1_4 PF07975.12 OWF43271.1 - 5 7.4 10.0 0.96 9.7 3.7 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain DZR PF12773.7 OWF43271.1 - 7.2 6.7 10.0 5e+02 0.8 10.0 2.4 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 OWF43271.1 - 8.4 6.7 11.5 8.9e+02 0.2 11.4 2.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Tnp_zf-ribbon_2 PF13842.6 OWF43272.1 - 0.00059 20.6 6.8 0.001 19.8 6.8 1.4 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon zf-C2H2 PF00096.26 OWF43274.1 - 2e-10 40.5 15.2 2.2e-05 24.7 1.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43274.1 - 2e-06 28.1 17.6 8e-05 23.2 1.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43274.1 - 5.1e-06 26.7 19.3 7.8e-05 22.9 2.9 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 OWF43274.1 - 7.4e-05 23.0 10.8 0.0019 18.5 0.4 2.9 3 0 0 3 3 2 2 Zinc-finger of C2H2 type Trm112p PF03966.16 OWF43274.1 - 0.0064 17.1 0.8 0.014 16.0 0.8 1.6 1 1 0 1 1 1 1 Trm112p-like protein PHD PF00628.29 OWF43274.1 - 0.012 15.5 6.7 0.066 13.1 1.4 2.4 2 0 0 2 2 2 0 PHD-finger zf-BED PF02892.15 OWF43274.1 - 0.016 15.2 0.5 0.016 15.2 0.5 3.2 2 1 1 3 3 3 0 BED zinc finger zinc_ribbon_15 PF17032.5 OWF43274.1 - 0.018 15.8 7.4 0.099 13.4 1.6 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 OWF43274.1 - 0.022 15.1 11.4 0.3 11.4 2.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-DNA_Pol PF08996.10 OWF43274.1 - 0.024 14.4 6.1 0.041 13.6 1.4 2.1 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 OWF43274.1 - 0.037 14.0 3.8 0.037 14.0 3.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_10 PF10058.9 OWF43274.1 - 0.046 13.5 5.6 0.28 11.0 2.4 2.4 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein LIM PF00412.22 OWF43274.1 - 0.047 13.9 10.2 0.64 10.3 8.4 2.7 1 1 1 2 2 2 0 LIM domain zinc_ribbon_12 PF11331.8 OWF43274.1 - 0.059 13.2 1.2 0.059 13.2 1.2 2.0 2 0 0 2 2 2 0 Probable zinc-ribbon domain RNA_POL_M_15KD PF02150.16 OWF43274.1 - 0.099 12.5 4.6 4 7.4 1.8 3.2 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit Elf1 PF05129.13 OWF43274.1 - 0.15 12.1 9.5 0.25 11.4 5.5 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_3rep PF18868.1 OWF43274.1 - 0.3 11.8 8.9 0.47 11.1 2.3 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 OWF43274.1 - 0.47 10.5 7.5 6.9 6.7 3.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Sec23_Sec24 PF04810.15 OWF43274.1 - 0.55 10.3 7.4 0.95 9.6 3.1 2.7 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 OWF43274.1 - 0.71 10.2 12.5 5.7 7.3 3.8 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc-ribbons_6 PF07191.12 OWF43274.1 - 0.76 9.8 10.0 2.4 8.2 1.4 2.7 1 1 2 3 3 3 0 zinc-ribbons Zn_ribbon_SprT PF17283.2 OWF43274.1 - 0.96 9.4 9.3 7.9 6.5 0.0 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf-RING_10 PF16685.5 OWF43274.1 - 2 8.6 15.3 3.2 7.9 3.1 2.5 1 1 2 3 3 3 0 zinc RING finger of MSL2 FYVE PF01363.21 OWF43274.1 - 2.4 8.3 15.2 13 6.0 14.2 2.5 1 1 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 OWF43274.1 - 3 8.0 11.7 8.1 6.7 4.8 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.16 OWF43274.1 - 8.3 6.7 16.3 1.2 9.4 0.2 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger zf-C2H2 PF00096.26 OWF43275.1 - 1.1e-11 44.5 26.2 0.00012 22.3 6.1 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43275.1 - 5.3e-10 39.3 21.6 3.4e-05 24.3 3.9 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43275.1 - 4.6e-08 33.1 6.7 4.6e-08 33.1 6.7 3.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF43275.1 - 2.5e-07 30.5 24.0 0.0048 16.9 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43275.1 - 1e-06 28.8 16.6 0.004 17.4 1.9 3.7 3 1 1 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF43275.1 - 1.1e-06 28.8 14.8 0.0051 17.2 1.3 3.8 3 1 0 3 3 3 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF43275.1 - 0.0012 19.0 10.3 0.0028 17.9 7.4 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding HNH_5 PF14279.6 OWF43275.1 - 0.0026 17.6 4.6 0.2 11.6 2.4 2.9 2 1 0 2 2 2 1 HNH endonuclease DUF2256 PF10013.9 OWF43275.1 - 0.004 17.2 3.4 2.4 8.3 0.1 3.3 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 OWF43275.1 - 0.0046 16.7 4.9 0.012 15.4 0.7 2.9 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OWF43275.1 - 0.019 15.3 15.3 0.29 11.5 3.8 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 OWF43275.1 - 0.037 14.7 5.6 0.35 11.6 5.4 2.1 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 OWF43275.1 - 0.045 14.2 5.9 0.76 10.3 1.1 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain ADK_lid PF05191.14 OWF43275.1 - 0.053 13.5 5.1 3.9 7.5 2.4 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-BED PF02892.15 OWF43275.1 - 0.088 12.8 14.1 1.5 8.9 4.0 3.2 2 1 1 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.10 OWF43275.1 - 0.097 12.8 7.1 1.2 9.3 2.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF2688 PF10892.8 OWF43275.1 - 0.17 11.3 3.2 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Prok-RING_1 PF14446.6 OWF43275.1 - 0.19 11.6 10.0 13 5.8 0.2 3.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 FYVE PF01363.21 OWF43275.1 - 0.23 11.6 12.9 1.4 9.2 12.9 2.1 1 1 0 1 1 1 0 FYVE zinc finger Elf1 PF05129.13 OWF43275.1 - 0.25 11.4 7.2 5.1 7.2 0.1 3.1 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Rhodanese_C PF12368.8 OWF43275.1 - 0.28 11.6 8.6 0.57 10.6 0.2 2.4 1 1 0 2 2 2 0 Rhodanase C-terminal zf-C2H2_9 PF16293.5 OWF43275.1 - 0.29 11.0 4.9 5.1 7.0 1.2 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 OWF43275.1 - 0.34 10.8 9.3 1.3 9.1 0.7 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.14 OWF43275.1 - 0.5 10.3 7.6 23 5.0 2.6 3.5 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS zinc_ribbon_15 PF17032.5 OWF43275.1 - 0.77 10.6 7.7 10 7.0 1.9 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf-HIT PF04438.16 OWF43275.1 - 1.9 8.4 9.3 3.9 7.4 0.5 3.2 3 0 0 3 3 3 0 HIT zinc finger DUF983 PF06170.12 OWF43275.1 - 2.1 8.8 6.7 8 6.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF983) zf-RING_5 PF14634.6 OWF43275.1 - 2.1 8.4 9.2 88 3.2 9.2 2.5 1 1 0 1 1 1 0 zinc-RING finger domain XPA_N PF01286.18 OWF43275.1 - 4.3 7.5 7.0 24 5.0 0.1 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-MYST PF17772.1 OWF43275.1 - 6.5 6.5 9.2 22 4.7 0.5 3.1 3 0 0 3 3 3 0 MYST family zinc finger domain HNH PF01844.23 OWF43275.1 - 8.9 6.6 11.5 69 3.7 0.2 3.2 2 1 0 2 2 2 0 HNH endonuclease zf-C2H2_4 PF13894.6 OWF43276.1 - 3.2e-14 52.4 32.1 6.7e-05 23.4 1.8 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43276.1 - 3.2e-13 49.4 38.8 7.7e-05 22.9 2.7 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43276.1 - 2e-10 40.6 30.9 0.00025 21.3 2.0 4.8 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF43276.1 - 5.4e-09 36.1 25.5 0.0013 18.9 2.1 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF43276.1 - 5.2e-08 33.0 21.7 0.019 15.4 1.6 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OWF43276.1 - 0.00011 22.0 7.2 0.05 13.5 0.1 3.5 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 OWF43276.1 - 0.0013 19.0 22.8 0.2 12.0 0.7 4.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) E6 PF00518.17 OWF43276.1 - 0.0016 18.8 1.7 0.0026 18.2 1.1 1.7 1 1 1 2 2 2 1 Early Protein (E6) zf-C2H2_6 PF13912.6 OWF43276.1 - 0.0088 16.0 36.9 0.072 13.1 3.9 5.2 4 1 0 4 4 4 3 C2H2-type zinc finger XPA_N PF01286.18 OWF43276.1 - 0.011 15.7 3.3 1.1 9.3 0.0 3.3 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_9 PF16293.5 OWF43276.1 - 0.025 14.4 4.5 4.7 7.1 0.2 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) HypA PF01155.19 OWF43276.1 - 0.031 14.3 5.8 17 5.5 5.9 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FPG_IleRS PF06827.14 OWF43276.1 - 0.048 13.5 11.1 2.1 8.3 0.3 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS CpXC PF14353.6 OWF43276.1 - 0.055 13.5 9.4 0.2 11.7 2.0 3.4 2 1 1 3 3 3 0 CpXC protein YhfH PF14149.6 OWF43276.1 - 0.06 13.3 3.2 37 4.4 0.1 3.4 3 0 0 3 3 3 0 YhfH-like protein zf_UBZ PF18439.1 OWF43276.1 - 0.11 12.1 10.3 3.5 7.3 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 OWF43276.1 - 0.12 12.0 14.4 4.2 7.1 1.5 4.2 3 1 1 4 4 4 0 MYST family zinc finger domain ARS2 PF04959.13 OWF43276.1 - 0.26 11.7 4.7 1.8 8.9 0.1 2.5 1 1 1 2 2 2 0 Arsenite-resistance protein 2 zinc_ribbon_15 PF17032.5 OWF43276.1 - 0.52 11.1 10.1 3.2 8.6 5.7 2.9 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 OWF43276.1 - 0.54 10.9 10.6 3.3 8.4 10.5 2.5 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 OWF43276.1 - 0.63 10.6 16.7 2.1 8.9 2.8 4.2 3 2 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DUF983 PF06170.12 OWF43276.1 - 0.71 10.3 5.1 34 4.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Zn-ribbon_8 PF09723.10 OWF43276.1 - 0.78 9.9 10.4 5.7 7.1 1.3 3.3 2 2 1 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 OWF43276.1 - 0.9 9.4 26.7 0.24 11.2 0.5 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type LIM PF00412.22 OWF43276.1 - 0.91 9.8 14.0 17 5.7 5.6 3.2 3 0 0 3 3 3 0 LIM domain zf-SNAP50_C PF12251.8 OWF43276.1 - 1 9.0 11.2 0.31 10.7 4.7 2.5 1 1 1 3 3 3 0 snRNA-activating protein of 50kDa MW C terminal DUF2256 PF10013.9 OWF43276.1 - 2.7 8.2 11.4 15 5.8 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2 PF00096.26 OWF43277.1 - 6.2e-09 35.8 45.0 0.00013 22.2 2.1 5.4 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43277.1 - 7e-09 35.8 41.8 0.01 16.6 3.6 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF43277.1 - 7e-07 29.1 23.2 0.0037 17.2 3.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43277.1 - 5.5e-05 23.3 23.3 0.18 12.1 0.3 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF43277.1 - 0.0035 17.7 5.9 0.0035 17.7 5.9 5.7 6 0 0 6 6 5 2 Zinc-finger double domain zinc_ribbon_15 PF17032.5 OWF43277.1 - 0.077 13.8 20.3 0.91 10.3 6.7 3.2 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 OWF43277.1 - 0.1 13.2 20.6 1.4 9.6 6.6 3.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 OWF43277.1 - 0.13 12.2 0.0 0.13 12.2 0.0 4.4 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 OWF43277.1 - 5 7.7 30.8 0.41 11.1 0.6 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-BED PF02892.15 OWF43277.1 - 5.2 7.2 27.3 0.38 10.8 1.8 4.0 3 1 1 4 4 4 0 BED zinc finger zf-C2H2_2 PF12756.7 OWF43277.1 - 6.2 7.2 34.1 0.77 10.1 0.7 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OWF43278.1 - 5.1e-14 51.8 30.6 0.00026 21.3 3.0 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43278.1 - 7.1e-13 48.2 27.1 0.0041 17.8 0.6 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43278.1 - 1.4e-08 34.8 26.6 1.8e-07 31.3 1.9 5.3 5 1 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.7 OWF43278.1 - 3.9e-08 33.4 18.5 0.0039 17.5 1.1 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF43278.1 - 2.5e-07 30.5 23.5 0.0014 18.6 2.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43278.1 - 1.5e-05 25.1 17.5 0.0047 17.2 0.5 4.5 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF43278.1 - 0.0004 20.7 14.3 0.92 9.9 0.3 3.8 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 OWF43278.1 - 0.0058 17.4 7.1 0.77 10.5 0.4 2.1 2 0 0 2 2 2 2 zinc-ribbon family HypA PF01155.19 OWF43278.1 - 0.0065 16.5 9.1 0.21 11.6 0.5 2.6 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 OWF43278.1 - 0.048 13.8 10.1 1.2 9.3 5.6 3.2 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 OWF43278.1 - 0.12 12.2 0.4 0.12 12.2 0.4 3.2 4 0 0 4 4 3 0 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 OWF43278.1 - 0.51 10.2 23.9 1.4 8.8 3.3 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type GATA PF00320.27 OWF43278.1 - 0.63 9.7 12.8 1.6 8.4 0.3 3.8 4 0 0 4 4 4 0 GATA zinc finger Prok-RING_1 PF14446.6 OWF43278.1 - 0.75 9.8 16.2 6 6.9 0.5 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DUF4187 PF13821.6 OWF43278.1 - 0.87 9.4 5.8 2.7 7.8 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4187) zf-C2H2_aberr PF17017.5 OWF43278.1 - 0.91 9.6 15.0 0.063 13.4 2.3 3.4 2 2 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_3 PF13878.6 OWF43278.1 - 1.6 8.6 15.9 9.2 6.2 0.3 4.4 4 1 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-AN1 PF01428.16 OWF43278.1 - 2 8.7 19.3 1 9.6 3.6 4.1 4 0 0 4 4 4 0 AN1-like Zinc finger DUF3268 PF11672.8 OWF43278.1 - 2.4 8.5 7.0 13 6.2 0.7 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C2HE PF16278.5 OWF43278.1 - 3.3 8.2 20.8 2.3 8.7 6.6 3.8 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 OWF43278.1 - 8.8 6.3 12.9 2.3 8.1 0.8 3.7 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 OWF43279.1 - 7.1e-14 51.4 28.0 0.0025 18.2 4.9 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43279.1 - 5.8e-13 48.5 30.3 0.0042 17.8 4.7 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43279.1 - 4e-09 36.5 21.4 0.011 16.0 0.2 5.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF43279.1 - 1.2e-08 34.9 27.9 0.00039 20.7 4.6 4.9 5 0 0 5 5 4 4 Zinc-finger double domain zf-met PF12874.7 OWF43279.1 - 1.4e-07 31.6 28.7 0.0021 18.4 1.6 5.3 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 OWF43279.1 - 0.0015 19.2 14.2 1.7 9.5 0.6 3.2 1 1 2 3 3 3 3 zinc-ribbon family zf-C2H2_11 PF16622.5 OWF43279.1 - 0.023 14.5 4.2 0.023 14.5 4.2 5.6 6 1 0 6 6 6 0 zinc-finger C2H2-type ROS_MUCR PF05443.11 OWF43279.1 - 0.076 13.1 1.3 2.3 8.3 0.0 2.3 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_6 PF13912.6 OWF43279.1 - 0.1 12.7 23.7 0.32 11.1 1.4 5.3 4 1 0 4 4 4 0 C2H2-type zinc finger ClpS PF02617.17 OWF43279.1 - 0.13 12.1 0.6 0.84 9.5 0.2 2.4 2 1 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS zf-RRPl_C4 PF17026.5 OWF43279.1 - 0.18 11.9 13.7 2.2 8.4 6.4 3.1 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-RING_7 PF02591.15 OWF43279.1 - 0.2 11.9 7.6 60 3.9 0.0 4.5 4 0 0 4 4 4 0 C4-type zinc ribbon domain Nudix_N_2 PF14803.6 OWF43279.1 - 0.56 10.2 0.0 0.56 10.2 0.0 4.1 5 0 0 5 5 5 0 Nudix N-terminal GFA PF04828.14 OWF43279.1 - 1.1 9.7 0.0 0.62 10.4 0.2 4.3 1 1 2 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_2 PF12756.7 OWF43279.1 - 3.1 8.2 22.7 23 5.4 4.1 4.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf_C2H2_13 PF18508.1 OWF43279.1 - 3.3 7.4 6.5 34 4.1 0.0 4.1 4 0 0 4 4 4 0 Zinc finger domain zf-C2H2_9 PF16293.5 OWF43279.1 - 3.5 7.5 9.4 7 6.6 0.6 3.1 3 1 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_aberr PF17017.5 OWF43279.1 - 6.4 6.9 16.4 0.086 13.0 4.2 3.1 2 2 1 3 3 3 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 OWF43280.1 - 1.1e-06 28.7 8.7 1.1e-06 28.7 8.7 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF43280.1 - 9.8e-06 25.7 32.0 0.001 19.4 2.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type DUF2866 PF11065.8 OWF43280.1 - 0.004 17.1 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2866) zf-C2H2_4 PF13894.6 OWF43280.1 - 0.0043 17.8 27.3 0.71 10.9 0.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 OWF43280.1 - 0.0087 16.3 7.3 0.45 10.8 0.2 4.0 4 0 0 4 4 4 1 zinc-ribbon zf-C2H2_jaz PF12171.8 OWF43280.1 - 0.081 13.2 16.1 1.7 9.0 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_7 PF15269.6 OWF43280.1 - 3 8.0 12.9 0.13 12.3 4.7 2.5 1 1 1 2 2 2 0 Zinc-finger zf-met PF12874.7 OWF43280.1 - 3.3 8.2 18.2 1.1 9.8 3.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Fer4_10 PF13237.6 OWF43280.1 - 5.6 7.2 12.6 1.3 9.1 8.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-C2H2 PF00096.26 OWF43281.1 - 8.9e-10 38.5 29.3 0.0019 18.5 6.1 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43281.1 - 1.4e-07 31.8 28.3 0.0046 17.7 5.5 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43281.1 - 4.3e-07 30.1 3.0 4.3e-07 30.1 3.0 4.4 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF43281.1 - 0.00018 21.7 20.7 0.026 14.8 2.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 OWF43281.1 - 0.0016 19.1 10.9 0.032 15.0 0.6 2.3 2 0 0 2 2 2 2 zinc-ribbon family C1_1 PF00130.22 OWF43281.1 - 0.0021 17.9 19.5 0.56 10.1 0.3 4.1 2 1 2 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 OWF43281.1 - 0.019 15.1 12.7 5.4 7.2 6.0 3.7 1 1 1 2 2 2 0 Zinc ribbon domain GATA PF00320.27 OWF43281.1 - 0.033 13.8 13.7 0.45 10.2 0.1 3.9 4 0 0 4 4 4 0 GATA zinc finger zf-met PF12874.7 OWF43281.1 - 0.046 14.1 19.0 1.4 9.4 0.5 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 OWF43281.1 - 0.053 14.0 17.6 0.056 13.9 1.5 4.0 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HNH_5 PF14279.6 OWF43281.1 - 0.053 13.4 9.2 1.1 9.2 0.0 3.8 3 1 0 3 3 3 0 HNH endonuclease zf_UBZ PF18439.1 OWF43281.1 - 0.086 12.4 8.5 19 4.9 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Mut7-C PF01927.16 OWF43281.1 - 0.094 12.8 11.8 0.19 11.8 6.8 2.8 1 1 2 3 3 3 0 Mut7-C RNAse domain zinc_ribbon_9 PF14369.6 OWF43281.1 - 0.11 12.7 10.8 2 8.7 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon zf-C2H2_6 PF13912.6 OWF43281.1 - 0.18 11.8 29.5 1.5 8.9 0.4 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Mss51 PF13824.6 OWF43281.1 - 0.54 10.4 12.0 0.51 10.5 0.2 2.8 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_7 PF02591.15 OWF43281.1 - 0.69 10.1 7.3 26 5.1 0.0 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain COX5B PF01215.19 OWF43281.1 - 1.7 8.4 8.4 24 4.6 0.3 3.6 2 1 1 4 4 4 0 Cytochrome c oxidase subunit Vb ADK_lid PF05191.14 OWF43281.1 - 2.6 8.1 11.9 0.8 9.7 0.5 3.7 3 1 1 4 4 4 0 Adenylate kinase, active site lid Gmx_para_CXXCG PF09535.10 OWF43281.1 - 3.2 7.0 9.0 6.8 5.9 1.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (Gmx_para_CXXCG) zf-ribbon_3 PF13248.6 OWF43281.1 - 3.7 7.1 16.1 3.3 7.2 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 OWF43282.1 - 1.2e-12 47.5 33.0 0.0019 18.9 2.0 5.6 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43282.1 - 1.2e-10 41.2 35.0 0.003 17.9 2.3 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.7 OWF43282.1 - 6.3e-06 26.4 15.4 0.024 15.0 0.8 5.0 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF43282.1 - 5.1e-05 23.5 26.3 0.012 15.9 0.6 5.7 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OWF43282.1 - 7.8e-05 22.9 14.5 0.0017 18.6 3.0 2.7 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 OWF43282.1 - 0.00061 20.1 32.8 0.0047 17.3 4.3 5.4 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF43282.1 - 0.0013 18.7 30.7 0.012 15.6 1.3 5.4 5 0 0 5 5 5 2 C2H2-type zinc finger C1_1 PF00130.22 OWF43282.1 - 0.023 14.6 28.2 0.39 10.6 7.5 4.1 2 2 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_3rep PF18868.1 OWF43282.1 - 0.28 11.9 15.7 1.2 9.9 10.7 3.4 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 OWF43282.1 - 0.43 10.7 16.5 18 5.6 0.3 5.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 OWF43282.1 - 0.65 9.8 24.8 2.1 8.2 1.0 5.6 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 OWF43282.1 - 1.4 9.1 18.2 1.8 8.7 2.2 4.5 2 1 3 5 5 5 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 OWF43282.1 - 2.1 8.1 19.5 2.2 8.0 1.3 4.4 3 2 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 OWF43282.1 - 2.5 7.8 16.0 15 5.3 0.1 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 OWF43282.1 - 3.6 7.6 15.4 1.2 9.2 2.3 3.9 1 1 4 5 5 5 0 CpXC protein zinc_ribbon_15 PF17032.5 OWF43282.1 - 5.1 7.9 17.1 2.5 8.9 1.5 3.2 3 1 1 4 4 3 0 zinc-ribbon family ADK_lid PF05191.14 OWF43282.1 - 8.5 6.5 18.0 0.48 10.5 1.5 4.3 4 1 0 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 OWF43283.1 - 2.4e-14 53.2 30.7 1.8e-05 24.9 2.7 5.3 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OWF43283.1 - 1.5e-09 37.8 42.6 0.0037 18.0 5.3 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 OWF43283.1 - 5.8e-09 36.1 31.5 0.0087 16.4 2.6 5.4 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OWF43283.1 - 1.4e-08 34.7 49.3 0.0079 16.6 6.0 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43283.1 - 3.1e-07 30.5 4.5 3.1e-07 30.5 4.5 5.8 5 1 0 5 5 5 2 Zinc-finger double domain zf-Di19 PF05605.12 OWF43283.1 - 2.6e-05 24.4 27.8 0.031 14.6 6.1 3.2 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OWF43283.1 - 0.0094 15.9 3.4 0.0094 15.9 3.4 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger DUF684 PF05075.14 OWF43283.1 - 0.074 12.0 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF684) zf-C2H2_2 PF12756.7 OWF43283.1 - 0.18 12.1 31.1 1.5 9.2 0.2 4.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 OWF43283.1 - 0.33 10.8 0.2 0.33 10.8 0.2 3.9 2 2 3 5 5 5 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 OWF43283.1 - 1.1 10.0 19.1 24 5.8 1.3 3.2 1 1 3 4 4 4 0 zinc-ribbon family BTB PF00651.31 OWF43284.1 - 4.3e-14 52.7 0.5 9.6e-14 51.6 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 OWF43284.1 - 1.3e-05 25.3 1.5 1.3e-05 25.3 1.5 4.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF43284.1 - 4.3e-05 24.0 28.8 0.97 10.4 0.3 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43284.1 - 0.079 13.3 23.3 0.28 11.5 0.5 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OWF43284.1 - 0.15 12.6 33.0 0.99 10.0 1.9 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3268 PF11672.8 OWF43284.1 - 6.4 7.1 9.7 0.12 12.7 2.0 2.0 2 0 0 2 2 2 0 zinc-finger-containing domain R-HINP1I PF11463.8 OWF43285.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease MADF_DNA_bdg PF10545.9 OWF43285.1 - 0.077 13.3 0.4 0.27 11.6 0.1 2.1 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like STE3 PF02076.15 OWF43286.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Pheromone A receptor LacI PF00356.21 OWF43286.1 - 0.16 11.8 1.9 8.5 6.3 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF4783 PF16022.5 OWF43287.1 - 0.072 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) DUF2761 PF10959.8 OWF43288.1 - 0.35 10.9 8.8 20 5.3 0.1 4.8 1 1 4 6 6 6 0 Protein of unknown function (DUF2761) Tnp_zf-ribbon_2 PF13842.6 OWF43289.1 - 0.018 15.8 6.9 0.028 15.2 6.9 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2_4 PF13894.6 OWF43290.1 - 2.8e-09 37.0 25.7 0.00067 20.3 0.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43290.1 - 5.1e-08 32.9 28.9 0.045 14.2 0.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43290.1 - 5.7e-06 26.5 24.0 0.0022 18.3 1.1 4.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF43290.1 - 7.9e-05 22.5 7.6 0.4 10.7 0.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43290.1 - 0.00023 21.4 15.2 0.094 13.0 0.8 3.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF43290.1 - 0.00041 20.6 14.4 0.098 13.1 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type XPA_N PF01286.18 OWF43290.1 - 0.0061 16.6 6.6 0.19 11.8 0.2 3.5 3 0 0 3 3 3 1 XPA protein N-terminal Sgf11 PF08209.11 OWF43290.1 - 0.009 15.5 2.9 1.6 8.4 0.0 3.2 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) zf-H2C2_5 PF13909.6 OWF43290.1 - 0.027 14.2 0.2 0.027 14.2 0.2 4.5 5 0 0 5 5 5 0 C2H2-type zinc-finger domain PyrI_C PF02748.15 OWF43290.1 - 0.043 13.7 7.6 5.5 7.0 0.8 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 OWF43290.1 - 0.054 13.8 1.2 0.054 13.8 1.2 2.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 OWF43290.1 - 0.073 13.3 10.3 0.89 9.8 3.0 3.0 1 1 2 3 3 3 0 LIM domain C1_2 PF03107.16 OWF43290.1 - 0.076 13.4 16.9 1.5 9.2 0.2 4.1 1 1 2 4 4 4 0 C1 domain zf_UBZ PF18439.1 OWF43290.1 - 0.08 12.6 5.2 6.1 6.5 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 OWF43290.1 - 0.089 13.1 11.1 0.32 11.3 3.8 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 OWF43290.1 - 0.12 12.3 8.9 3.3 7.7 0.7 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_1 PF00130.22 OWF43290.1 - 0.2 11.6 9.7 0.63 10.0 2.0 2.6 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 OWF43290.1 - 0.28 11.3 6.8 10 6.3 0.3 3.3 1 1 2 3 3 3 0 KIAA1045 RING finger zf-3CxxC PF13695.6 OWF43290.1 - 0.47 10.9 10.3 1.5 9.3 0.7 2.9 2 1 1 3 3 3 0 Zinc-binding domain DUF629 PF04780.12 OWF43290.1 - 0.51 8.8 8.6 0.73 8.3 1.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF629) zf-Sec23_Sec24 PF04810.15 OWF43290.1 - 0.61 10.2 9.1 13 5.9 0.6 3.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger FYVE PF01363.21 OWF43290.1 - 0.73 10.0 20.2 0.7 10.1 4.1 3.2 1 1 2 3 3 3 0 FYVE zinc finger UBZ_FAAP20 PF15750.5 OWF43290.1 - 0.98 9.4 5.0 23 5.0 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Actin_micro PF17003.5 OWF43290.1 - 1 8.5 11.0 1.4 8.0 1.3 2.6 1 1 2 3 3 3 0 Putative actin-like family zf_ZIC PF18366.1 OWF43290.1 - 3.4 7.8 7.7 3.7 7.7 0.5 3.2 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-AN1 PF01428.16 OWF43290.1 - 4.5 7.5 14.3 8.2 6.7 0.3 4.0 3 1 1 4 4 4 0 AN1-like Zinc finger Mut7-C PF01927.16 OWF43290.1 - 6.4 6.9 9.6 18 5.4 8.6 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain Tnp_zf-ribbon_2 PF13842.6 OWF43291.1 - 5.1 8.0 9.9 7.9 7.4 9.9 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon BTB PF00651.31 OWF43292.1 - 2.5e-13 50.2 0.2 4.3e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain Tnp_zf-ribbon_2 PF13842.6 OWF43292.1 - 0.52 11.1 10.2 1.1 10.1 10.2 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon BTB PF00651.31 OWF43293.1 - 3.7e-13 49.7 0.4 6.9e-13 48.8 0.4 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 OWF43293.1 - 6.5e-10 38.9 34.7 0.041 14.3 2.6 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43293.1 - 2e-07 31.2 27.3 0.14 13.1 1.9 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 OWF43293.1 - 5.6e-06 26.6 19.7 0.035 14.5 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OWF43293.1 - 0.00027 21.2 28.5 0.011 16.1 0.4 5.1 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 OWF43293.1 - 0.014 15.1 12.3 0.23 11.2 1.1 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OWF43293.1 - 0.03 14.6 19.4 1.8 9.0 0.7 5.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 OWF43293.1 - 0.064 13.1 3.7 0.066 13.0 0.2 2.8 1 1 1 2 2 2 0 GAGA factor DUF629 PF04780.12 OWF43293.1 - 0.54 8.7 7.3 1.5 7.2 7.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.6 OWF43293.1 - 1.1 9.3 21.9 0.45 10.6 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2321 PF10083.9 OWF43293.1 - 1.7 8.3 6.7 12 5.4 1.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2 PF00096.26 OWF43294.1 - 1.5e-13 50.3 33.5 0.0016 18.8 0.1 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43294.1 - 1.1e-10 41.5 31.5 0.01 16.6 1.3 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 OWF43294.1 - 2.2e-08 34.2 29.2 0.00064 20.0 2.3 5.3 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OWF43294.1 - 5.7e-08 32.8 31.9 0.0045 17.4 4.0 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF43294.1 - 1.4e-07 31.4 23.5 0.0053 16.7 2.7 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43294.1 - 2.2e-07 31.0 30.1 0.16 12.3 5.1 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 OWF43294.1 - 0.00092 18.8 0.6 0.00092 18.8 0.6 4.1 1 1 4 5 5 4 2 Zinc-fingers and homeoboxes C2H2 finger domain Elf1 PF05129.13 OWF43294.1 - 0.0072 16.4 13.4 0.064 13.3 2.6 2.6 1 1 0 2 2 2 2 Transcription elongation factor Elf1 like zf_UBZ PF18439.1 OWF43294.1 - 0.0084 15.7 12.4 1.5 8.5 0.1 4.7 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OWF43294.1 - 0.03 14.4 1.2 0.03 14.4 1.2 3.8 3 1 0 4 4 4 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 OWF43294.1 - 0.053 13.3 4.0 0.053 13.3 4.0 5.0 5 1 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_3 PF13878.6 OWF43294.1 - 0.054 13.3 0.4 0.054 13.3 0.4 4.8 4 1 1 5 5 5 0 zinc-finger of acetyl-transferase ESCO zinc_ribbon_15 PF17032.5 OWF43294.1 - 0.054 14.3 16.8 2 9.2 8.9 3.0 1 1 2 3 3 3 0 zinc-ribbon family HypA PF01155.19 OWF43294.1 - 0.41 10.7 15.5 0.57 10.2 0.7 3.1 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF899 PF05988.12 OWF43294.1 - 1.2 8.7 6.7 0.14 11.7 1.1 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF899) zf-C2H2_9 PF16293.5 OWF43294.1 - 1.5 8.7 14.3 2.1 8.2 0.6 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 OWF43294.1 - 3.7 7.6 16.3 7.7 6.6 0.4 4.3 2 2 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 OWF43294.1 - 3.8 7.9 23.4 1.2e+03 -0.1 11.9 4.3 1 1 2 3 3 2 0 C2H2 type zinc-finger (2 copies) zf_Hakai PF18408.1 OWF43294.1 - 5.6 6.8 0.0 5.6 6.8 0.0 4.1 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain zf-C2H2_jaz PF12171.8 OWF43295.1 - 1.3e-06 28.6 24.7 4.8e-05 23.5 1.9 3.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OWF43295.1 - 2.1e-06 28.1 26.8 0.00032 21.3 1.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43295.1 - 2.6e-06 27.6 32.5 0.004 17.5 6.4 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OWF43295.1 - 0.00014 21.7 1.2 0.00014 21.7 1.2 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger Spt46 PF17734.1 OWF43295.1 - 0.0082 16.0 9.7 0.013 15.3 1.7 2.1 1 1 1 2 2 2 1 Spermatogenesis-associated protein 46 zf-piccolo PF05715.13 OWF43295.1 - 0.015 15.4 3.0 0.015 15.4 3.0 1.7 2 0 0 2 2 2 0 Piccolo Zn-finger zf-MYST PF17772.1 OWF43295.1 - 0.026 14.1 0.1 0.026 14.1 0.1 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 OWF43295.1 - 0.027 14.9 30.1 0.048 14.1 5.7 3.6 4 0 0 4 4 4 0 Zinc-finger double domain BolA PF01722.18 OWF43295.1 - 0.046 14.0 2.7 0.74 10.1 0.0 2.4 2 1 1 3 3 2 0 BolA-like protein zf-CHCC PF10276.9 OWF43295.1 - 0.067 13.3 0.7 0.067 13.3 0.7 2.5 3 0 0 3 3 3 0 Zinc-finger domain Baculo_IE-1 PF05290.11 OWF43295.1 - 0.12 12.3 6.8 4.7 7.2 0.5 2.8 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) Vps36-NZF-N PF16988.5 OWF43295.1 - 0.13 11.7 2.4 2.4 7.6 0.4 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-met PF12874.7 OWF43295.1 - 0.16 12.4 1.5 0.16 12.4 1.5 3.1 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 OWF43295.1 - 0.16 12.7 10.4 2.4 8.9 3.9 2.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 OWF43295.1 - 0.2 11.3 9.8 1 9.0 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger FYVE_2 PF02318.16 OWF43295.1 - 0.27 11.5 10.0 0.16 12.2 6.2 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger zf-C2H2_8 PF15909.5 OWF43295.1 - 0.29 11.5 0.2 0.29 11.5 0.2 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon Elf1 PF05129.13 OWF43295.1 - 0.29 11.2 9.7 0.26 11.4 5.2 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-CCHC_2 PF13696.6 OWF43295.1 - 0.32 10.9 0.3 0.32 10.9 0.3 3.4 4 0 0 4 4 3 0 Zinc knuckle PyrI_C PF02748.15 OWF43295.1 - 0.4 10.6 11.1 19 5.2 2.4 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 OWF43295.1 - 1 9.5 9.6 3.4 7.9 3.4 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 OWF43295.1 - 1.3 9.4 17.0 7.8 6.9 0.1 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.14 OWF43295.1 - 1.4 9.0 12.6 2.8 7.9 1.7 3.1 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif FYVE PF01363.21 OWF43295.1 - 2.6 8.3 19.9 11 6.2 0.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger ADK_lid PF05191.14 OWF43295.1 - 4.2 7.4 12.7 6.6 6.8 2.9 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2 PF00096.26 OWF43296.1 - 1.5e-08 34.6 36.9 0.00013 22.2 2.6 4.6 4 1 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43296.1 - 2.1e-06 28.1 18.2 0.003 18.3 1.6 4.5 4 1 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43296.1 - 6e-06 26.4 1.0 6e-06 26.4 1.0 4.7 4 2 0 4 4 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF43296.1 - 0.0054 17.0 5.3 0.014 15.6 2.9 4.6 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF43296.1 - 0.015 15.7 3.3 0.015 15.7 3.3 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Elf1 PF05129.13 OWF43296.1 - 0.036 14.1 1.0 0.036 14.1 1.0 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like BolA PF01722.18 OWF43296.1 - 0.039 14.2 0.2 0.039 14.2 0.2 2.4 2 1 0 2 2 2 0 BolA-like protein Zn-ribbon_8 PF09723.10 OWF43296.1 - 0.059 13.5 14.1 5 7.3 0.5 2.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 OWF43296.1 - 0.063 13.3 0.7 0.063 13.3 0.7 4.6 4 1 0 4 4 3 0 C2H2-type zinc finger I-set PF07679.16 OWF43296.1 - 0.14 12.2 0.4 0.23 11.6 0.1 1.6 2 0 0 2 2 2 0 Immunoglobulin I-set domain Tudor_2 PF18104.1 OWF43296.1 - 0.2 11.4 0.6 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Desulfoferrod_N PF06397.12 OWF43296.1 - 0.37 10.5 0.2 0.37 10.5 0.2 3.0 3 1 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain TF_Zn_Ribbon PF08271.12 OWF43296.1 - 0.52 9.9 0.0 0.52 9.9 0.0 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zf_UBZ PF18439.1 OWF43296.1 - 0.96 9.1 12.1 3.2 7.4 0.1 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 OWF43296.1 - 5.5 7.8 17.5 14 6.5 1.0 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2 PF00096.26 OWF43297.1 - 2e-09 37.4 31.0 0.0029 18.0 2.1 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43297.1 - 4.5e-08 33.3 28.0 0.036 14.9 1.6 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43297.1 - 1.3e-05 25.4 3.0 1.3e-05 25.4 3.0 3.9 4 1 0 4 4 3 2 Zinc-finger double domain zf-met PF12874.7 OWF43297.1 - 2.9e-05 24.3 15.8 0.0078 16.6 0.3 4.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF43297.1 - 0.00069 19.8 15.8 0.063 13.6 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Fer4_8 PF13183.6 OWF43297.1 - 0.0055 17.1 8.7 0.0055 17.1 8.7 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain zf-C2H2_6 PF13912.6 OWF43297.1 - 0.059 13.4 3.4 0.059 13.4 3.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OWF43297.1 - 0.08 12.6 0.4 0.08 12.6 0.4 2.9 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Fer4_18 PF13746.6 OWF43297.1 - 0.13 12.5 6.4 3.6 7.8 2.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 OWF43297.1 - 0.52 10.5 17.4 4.8 7.4 2.0 3.0 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 OWF43297.1 - 0.82 9.8 15.7 1.2 9.4 6.2 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 OWF43297.1 - 1.8 9.2 18.6 0.79 10.3 0.2 3.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain zf_UBZ PF18439.1 OWF43297.1 - 2.4 7.8 11.9 10 5.8 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Fer4_21 PF14697.6 OWF43297.1 - 8 6.7 17.3 6.5 7.0 0.7 3.4 1 1 1 3 3 3 0 4Fe-4S dicluster domain zf-C2H2_4 PF13894.6 OWF43299.1 - 4.1e-12 45.8 21.8 0.00039 21.0 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43299.1 - 3.9e-09 36.5 27.2 0.00017 21.9 0.8 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43299.1 - 1e-07 32.0 16.1 0.00044 20.6 1.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2HC_2 PF13913.6 OWF43299.1 - 7.7e-05 22.5 7.6 0.012 15.5 0.1 3.6 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 OWF43299.1 - 0.00015 21.6 23.0 0.0067 16.4 1.7 4.1 5 0 0 5 5 5 3 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 OWF43299.1 - 0.0011 19.6 7.9 0.022 15.5 0.6 2.6 1 1 2 3 3 3 2 zinc-ribbon family zf_C2H2_ZHX PF18387.1 OWF43299.1 - 0.0054 16.3 9.4 0.059 13.0 0.1 3.5 2 1 2 4 4 4 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 OWF43299.1 - 0.0063 16.8 14.2 0.026 14.8 0.6 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 OWF43299.1 - 0.043 14.0 3.0 8.8 6.6 0.0 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain XPA_N PF01286.18 OWF43299.1 - 0.049 13.7 4.6 17 5.5 0.1 3.5 3 0 0 3 3 3 0 XPA protein N-terminal zf-met PF12874.7 OWF43299.1 - 0.054 13.9 0.1 0.054 13.9 0.1 3.5 4 0 0 4 4 3 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 OWF43299.1 - 0.086 13.0 1.3 12 6.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DZR PF12773.7 OWF43299.1 - 0.1 12.6 9.6 14 5.8 9.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 OWF43299.1 - 0.13 12.3 4.3 1.3 9.0 2.7 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 OWF43299.1 - 0.18 11.4 14.1 1.2 8.8 0.2 3.6 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 OWF43299.1 - 0.32 10.8 0.1 0.32 10.8 0.1 4.4 4 1 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 OWF43299.1 - 0.4 11.0 7.4 0.2 12.0 1.2 2.9 1 1 3 4 4 4 0 C2H2-type zinc ribbon CpXC PF14353.6 OWF43299.1 - 1.4 9.0 5.2 2.7 8.1 2.1 2.5 2 1 0 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 OWF43299.1 - 5.4 7.2 16.6 2 8.6 2.5 3.1 2 1 2 4 4 4 0 Zinc ribbon domain zf-MYST PF17772.1 OWF43299.1 - 7.5 6.2 13.5 1.3 8.7 1.6 3.7 2 2 2 4 4 4 0 MYST family zinc finger domain Spt46 PF17734.1 OWF43299.1 - 8.5 6.1 9.3 35 4.1 0.0 3.0 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 Tnp_zf-ribbon_2 PF13842.6 OWF43300.1 - 0.42 11.5 9.2 0.17 12.7 6.7 1.7 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon BTB PF00651.31 OWF43301.1 - 1.4e-14 54.3 0.1 2.4e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 OWF43301.1 - 3e-05 24.5 15.5 0.012 16.4 1.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43301.1 - 0.55 10.8 10.6 1.3 9.6 2.9 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 OWF43301.1 - 0.87 10.2 17.2 0.11 13.0 1.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OWF43301.1 - 1.4 8.8 9.6 0.69 9.7 2.8 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OWF43301.1 - 2 8.8 5.8 12 6.3 0.1 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Adeno_E4_ORF3 PF06931.11 OWF43303.1 - 0.92 9.7 13.7 19 5.5 0.4 5.8 1 1 4 6 6 6 0 Mastadenovirus E4 ORF3 protein NACHT PF05729.12 OWF43304.1 - 2.6e-14 53.5 0.0 5.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OWF43304.1 - 1.1e-08 35.7 1.0 3.4e-08 34.1 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain WD40 PF00400.32 OWF43304.1 - 6.1e-07 30.0 0.7 0.058 14.3 0.0 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat ATPase_2 PF01637.18 OWF43304.1 - 6.2e-05 23.0 0.2 0.00055 19.9 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OWF43304.1 - 0.00013 22.3 0.0 0.00045 20.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.8 OWF43304.1 - 0.0026 16.5 3.7 0.22 10.1 0.1 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF4062 PF13271.6 OWF43304.1 - 0.0029 18.0 0.0 0.0098 16.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) AAA PF00004.29 OWF43304.1 - 0.0051 17.2 2.5 0.012 16.1 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PALB2_WD40 PF16756.5 OWF43304.1 - 0.34 9.8 3.7 14 4.5 0.1 3.5 3 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain GNAT_acetyltr_2 PF13718.6 OWF43305.1 - 9.7e-100 332.6 0.1 2.2e-98 328.2 0.0 2.4 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OWF43305.1 - 4.4e-76 255.7 9.0 8.9e-76 254.7 9.0 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OWF43305.1 - 2e-63 213.4 0.0 8.1e-63 211.5 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 OWF43305.1 - 7.8e-34 115.5 0.1 2.5e-33 113.8 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 OWF43305.1 - 0.00012 22.2 0.0 0.00053 20.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF43305.1 - 0.0014 19.0 0.0 0.0058 17.0 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD PF00270.29 OWF43305.1 - 0.056 13.2 0.1 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase IgGFc_binding PF17517.2 OWF43306.1 - 1.1e-34 120.1 2.3 1.1e-34 120.1 2.3 1.8 2 0 0 2 2 2 1 IgGFc binding protein cwf21 PF08312.12 OWF43306.1 - 0.096 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 cwf21 domain Helveticin_J PF17312.2 OWF43306.1 - 0.11 11.6 0.4 0.35 9.9 0.2 1.8 2 0 0 2 2 2 0 Bacteriocin helveticin-J Pro_Al_protease PF02983.14 OWF43306.1 - 0.73 9.9 2.4 5 7.3 0.8 2.3 2 0 0 2 2 2 0 Alpha-lytic protease prodomain CD225 PF04505.12 OWF43307.1 - 1.8e-10 40.8 0.4 3e-10 40.1 0.4 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein MpPF26 PF07666.11 OWF43307.1 - 0.0084 16.2 1.1 0.013 15.6 1.1 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 26 DUF3671 PF12420.8 OWF43307.1 - 0.012 15.7 0.5 0.017 15.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function Nckap1 PF09735.9 OWF43308.1 - 0 1563.1 24.2 0 1562.9 24.2 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein T6SS_VipA PF05591.12 OWF43308.1 - 0.052 13.4 0.3 0.16 11.8 0.3 1.8 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Claudin_2 PF13903.6 OWF43309.1 - 1.5 8.5 25.4 3.1 7.5 21.1 2.7 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF281 PF03436.13 OWF43309.1 - 2.2 8.8 10.3 0.64 10.5 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF281) DUF5379 PF17350.2 OWF43309.1 - 9.6 6.5 9.9 3.5 8.0 3.9 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5379) RRM_1 PF00076.22 OWF43310.1 - 1.8e-36 123.8 0.0 1.1e-14 54.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF43310.1 - 0.0012 18.8 0.5 0.0043 17.1 0.2 2.0 3 0 0 3 3 3 1 RNA binding motif THRAP3_BCLAF1 PF15440.6 OWF43310.1 - 0.071 12.1 9.9 0.13 11.3 9.9 1.4 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Myb_DNA-bind_2 PF08914.11 OWF43310.1 - 0.15 12.3 0.3 6.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Rap1 Myb domain DUF2431 PF10354.9 OWF43311.1 - 1.1e-48 165.7 0.2 2.4e-48 164.6 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 OWF43311.1 - 2.6e-05 24.5 0.0 7.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain MTS PF05175.14 OWF43311.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HZS_alpha PF18582.1 OWF43311.1 - 0.036 14.5 0.0 12 6.5 0.0 2.8 2 0 0 2 2 2 0 Hydrazine synthase alpha subunit middle domain UPF0020 PF01170.18 OWF43311.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DEAD PF00270.29 OWF43312.1 - 2.4e-41 141.4 0.0 5.6e-41 140.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF43312.1 - 4.8e-24 84.8 0.3 2.8e-23 82.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OWF43312.1 - 1.9e-19 69.6 0.1 4.1e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C_2 PF13307.6 OWF43312.1 - 0.06 13.5 0.2 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain Tudor_4 PF18358.1 OWF43313.1 - 9.1e-29 98.8 0.5 9.1e-29 98.8 0.5 2.3 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain SET PF00856.28 OWF43313.1 - 2e-25 90.1 9.6 4.9e-24 85.6 3.9 3.6 2 1 0 2 2 2 1 SET domain TUDOR_5 PF18359.1 OWF43313.1 - 1.6e-24 85.3 3.7 1.5e-22 79.1 1.1 2.7 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Pre-SET PF05033.16 OWF43313.1 - 2.7e-16 60.2 10.8 2.7e-16 60.2 10.8 3.7 4 0 0 4 4 3 1 Pre-SET motif THAP PF05485.12 OWF43313.1 - 7.1e-09 36.5 2.9 1.1e-07 32.6 1.2 3.3 2 0 0 2 2 2 1 THAP domain DUF5604 PF18300.1 OWF43313.1 - 3.2e-08 33.4 1.1 7e-08 32.3 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5604) MBD PF01429.19 OWF43313.1 - 8.8e-07 28.6 0.0 2.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain Tudor_3 PF18115.1 OWF43313.1 - 1.5e-06 27.9 0.7 0.00036 20.3 0.1 3.3 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain DUF1325 PF07039.11 OWF43313.1 - 0.00018 21.6 0.1 0.0026 17.8 0.1 2.7 1 1 0 1 1 1 1 SGF29 tudor-like domain Med30 PF11315.8 OWF43313.1 - 0.014 15.6 1.4 0.035 14.3 1.4 1.6 1 0 0 1 1 1 0 Mediator complex subunit 30 COG2 PF06148.11 OWF43313.1 - 0.09 12.9 1.7 0.28 11.3 1.7 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 OWF43313.1 - 0.16 9.8 1.6 0.32 8.9 1.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RAG1_imp_bd PF12560.8 OWF43313.1 - 0.81 9.2 16.7 0.053 13.1 0.6 3.2 2 1 0 3 3 3 0 RAG1 importin binding Cupin_8 PF13621.6 OWF43314.1 - 2.4e-83 279.8 0.7 2.9e-83 279.5 0.7 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OWF43314.1 - 0.0042 17.5 0.5 0.017 15.5 0.1 2.3 2 1 0 2 2 2 1 JmjC domain, hydroxylase Methyltransf_31 PF13847.6 OWF43315.1 - 1.6e-22 80.0 0.0 2.4e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF43315.1 - 1.2e-15 58.1 0.0 1.9e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF43315.1 - 2.9e-15 56.7 0.0 7e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF43315.1 - 7.7e-15 55.1 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF43315.1 - 3.1e-14 53.4 0.0 8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF43315.1 - 4.3e-08 32.8 0.0 6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OWF43315.1 - 5.3e-07 29.3 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 OWF43315.1 - 4.9e-05 23.0 0.1 8.2e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 OWF43315.1 - 0.0002 21.0 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 OWF43315.1 - 0.00064 19.2 0.0 0.0016 17.9 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 OWF43315.1 - 0.00077 18.9 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OWF43315.1 - 0.00085 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 OWF43315.1 - 0.001 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OWF43315.1 - 0.0017 18.4 0.8 0.0025 17.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 OWF43315.1 - 0.0026 16.9 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_16 PF10294.9 OWF43315.1 - 0.009 15.8 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_9 PF08003.11 OWF43315.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 OWF43315.1 - 0.017 14.4 0.2 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 OWF43315.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MarR_2 PF12802.7 OWF43315.1 - 0.086 12.7 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 MarR family Colipase PF01114.18 OWF43315.1 - 0.18 11.5 0.7 0.49 10.1 0.7 1.7 1 0 0 1 1 1 0 Colipase, N-terminal domain COesterase PF00135.28 OWF43316.1 - 5.7e-28 98.1 0.0 6.5e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family 7tm_1 PF00001.21 OWF43317.1 - 1.6e-41 142.4 24.9 2.4e-41 141.8 24.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF43317.1 - 8.6e-07 29.0 20.8 2.5e-06 27.4 20.8 1.8 1 1 0 1 1 1 1 Olfactory receptor GSIII_N PF12437.8 OWF43317.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal ESSS PF10183.9 OWF43319.1 - 0.00041 20.5 1.0 77 3.6 0.0 6.3 1 1 5 6 6 6 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ski_Sno PF02437.17 OWF43319.1 - 0.051 13.3 13.1 9.9 6.0 0.0 7.0 1 1 8 10 10 10 0 SKI/SNO/DAC family DUF4046 PF13255.6 OWF43319.1 - 1.9 9.1 4.8 1.3e+02 3.2 0.0 5.5 2 1 5 8 8 8 0 Protein of unknown function (DUF4046) MgtE_N PF03448.17 OWF43321.1 - 2.7e-05 24.7 0.0 25 5.6 0.0 4.5 1 1 4 6 6 6 3 MgtE intracellular N domain Ery_res_leader2 PF08057.11 OWF43321.1 - 0.0024 17.9 46.8 30 5.6 0.1 20.9 5 4 21 26 26 26 1 Erythromycin resistance leader peptide Drf_FH1 PF06346.12 OWF43321.1 - 0.17 11.6 12.9 1.7e+02 1.8 8.6 4.1 1 1 1 2 2 2 0 Formin Homology Region 1 CBP_BcsR PF10945.8 OWF43322.1 - 0.0015 18.0 0.3 1.8e+02 1.7 0.0 6.7 4 2 3 7 7 7 0 Cellulose biosynthesis protein BcsR SAF PF08666.12 OWF43322.1 - 0.067 13.8 3.6 2.7e+02 2.3 0.0 6.9 3 2 2 5 5 5 0 SAF domain TAL_effector PF03377.13 OWF43323.1 - 0.17 12.2 2.1 33 4.9 0.1 3.7 3 1 0 3 3 3 0 TAL effector repeat Glyco_transf_10 PF00852.19 OWF43325.1 - 1.1e-47 162.0 0.7 2.1e-47 161.1 0.7 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF43325.1 - 5.1e-18 65.5 0.4 1.3e-17 64.2 0.4 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF2787 PF10980.8 OWF43325.1 - 0.012 15.8 0.1 0.028 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) 7tm_1 PF00001.21 OWF43326.1 - 7.5e-57 192.6 13.6 1.1e-56 192.1 13.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF43326.1 - 1.2e-10 41.2 12.0 1.8e-10 40.6 12.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF43326.1 - 2.9e-10 40.2 17.5 2.9e-10 40.2 17.5 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF43326.1 - 0.0013 18.5 10.1 0.0013 18.5 10.1 2.0 2 1 0 2 2 2 1 Olfactory receptor TarH PF02203.15 OWF43326.1 - 0.21 11.5 0.2 0.59 10.0 0.0 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue 2OG-FeII_Oxy_2 PF13532.6 OWF43328.1 - 5.6e-29 101.7 0.0 7.3e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB_2 PF02214.22 OWF43329.1 - 6.8e-19 68.0 0.0 1.3e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OWF43329.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Thioredoxin PF00085.20 OWF43330.1 - 4.2e-10 39.5 0.0 7.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DnaJ PF00226.31 OWF43331.1 - 1.8e-18 66.4 0.9 2.5e-18 65.9 0.9 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 OWF43331.1 - 2.9e-11 42.9 4.8 5.3e-11 42.1 2.6 2.2 2 0 0 2 2 2 1 CSL zinc finger DUF4461 PF14688.6 OWF43332.1 - 0.054 13.3 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) zf-C2H2 PF00096.26 OWF43333.1 - 2.7e-21 74.7 51.0 5.3e-07 29.7 3.2 6.8 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43333.1 - 3.9e-21 74.5 43.8 9.9e-09 35.2 0.9 6.9 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF43333.1 - 3.8e-16 58.4 54.4 0.00023 21.7 3.1 6.9 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43333.1 - 1.1e-09 38.3 28.4 0.008 16.4 1.0 6.1 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF43333.1 - 1.4e-07 31.3 41.9 0.00039 20.3 3.5 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger SET PF00856.28 OWF43333.1 - 1.8e-06 28.4 0.3 5e-06 27.0 0.1 1.8 2 1 0 2 2 1 1 SET domain zf-met PF12874.7 OWF43333.1 - 2e-05 24.8 34.0 0.053 13.9 1.2 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OWF43333.1 - 0.001 18.9 22.6 0.26 11.2 0.3 5.7 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 OWF43333.1 - 0.0078 16.5 29.5 0.7 10.3 2.2 5.8 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OWF43333.1 - 0.011 15.4 2.8 0.011 15.4 2.8 5.7 6 0 0 6 6 5 0 zinc-finger C2H2-type zf-Di19 PF05605.12 OWF43333.1 - 0.016 15.5 24.2 2 8.8 5.5 3.7 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 OWF43333.1 - 0.046 14.5 21.1 0.16 12.8 1.3 3.7 1 1 2 3 3 3 0 zinc-ribbon family FYVE PF01363.21 OWF43333.1 - 0.25 11.5 30.5 9.8 6.4 11.2 4.0 1 1 3 4 4 4 0 FYVE zinc finger PyrI_C PF02748.15 OWF43333.1 - 0.47 10.4 22.6 1.1 9.2 0.2 5.6 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 OWF43333.1 - 0.99 9.5 13.2 14 5.9 0.0 4.8 5 0 0 5 5 5 0 Zinc-finger domain Zn-ribbon_8 PF09723.10 OWF43333.1 - 1.6 8.9 23.0 2.1 8.5 0.7 4.8 3 2 1 4 4 4 0 Zinc ribbon domain zf_UBZ PF18439.1 OWF43333.1 - 2.5 7.8 19.1 0.91 9.2 0.1 5.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger HNH_5 PF14279.6 OWF43333.1 - 5 7.1 18.5 2.1 8.2 1.3 5.0 5 1 0 5 5 5 0 HNH endonuclease DUF2256 PF10013.9 OWF43333.1 - 9.3 6.5 19.6 20 5.4 0.1 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF1505 PF07403.11 OWF43334.1 - 0.24 11.6 5.8 3.8 7.7 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1505) Chlam_OMP6 PF03504.13 OWF43334.1 - 3.4 8.0 4.3 43 4.5 0.2 3.2 1 1 3 4 4 4 0 Chlamydia cysteine-rich outer membrane protein 6 Ras PF00071.22 OWF43335.1 - 1e-23 83.7 0.4 2e-23 82.8 0.4 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF43335.1 - 2.6e-05 24.4 0.0 0.0046 17.2 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OWF43335.1 - 0.00071 19.5 0.4 1 9.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OWF43335.1 - 0.047 14.1 0.1 0.079 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OWF43335.1 - 0.082 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 OWF43335.1 - 0.094 11.8 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Arf PF00025.21 OWF43335.1 - 0.12 11.8 0.1 17 4.8 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 OWF43335.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 OWF43335.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Utp21 PF04192.12 OWF43336.1 - 0.17 11.4 7.5 4.9 6.6 7.4 2.5 1 1 0 1 1 1 0 Utp21 specific WD40 associated putative domain YhfC PF10086.9 OWF43336.1 - 0.24 10.8 6.5 4.7 6.5 0.4 3.0 1 1 2 3 3 3 0 YhfC intramembrane metalloprotease Viral_DNA_Zn_bi PF03728.13 OWF43336.1 - 0.38 11.4 18.3 2.1 9.0 0.6 3.6 1 1 3 4 4 4 0 Viral DNA-binding protein, zinc binding domain Pox_H7 PF04787.12 OWF43336.1 - 0.42 11.1 3.0 7.1 7.1 0.1 2.9 1 1 2 3 3 3 0 Late protein H7 Ras PF00071.22 OWF43337.1 - 2.3e-24 85.8 0.4 4.6e-24 84.8 0.4 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF43337.1 - 1.2e-06 28.7 0.1 0.005 17.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OWF43337.1 - 1.5e-05 24.9 1.6 0.034 14.1 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase ATP-synt_ab PF00006.25 OWF43337.1 - 0.0022 17.7 0.2 0.0081 15.8 0.2 1.8 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 OWF43337.1 - 0.0042 17.5 0.1 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 OWF43337.1 - 0.0085 15.7 0.7 0.21 11.1 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF43337.1 - 0.01 15.9 0.1 0.076 13.1 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF43337.1 - 0.012 15.9 0.1 0.038 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OWF43337.1 - 0.025 14.3 0.2 0.093 12.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 OWF43337.1 - 0.026 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_7 PF12775.7 OWF43337.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 OWF43337.1 - 0.03 14.7 0.2 0.088 13.2 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OWF43337.1 - 0.038 13.9 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Latarcin PF10279.9 OWF43337.1 - 0.058 13.8 1.0 0.14 12.6 0.2 2.1 2 0 0 2 2 1 0 Latarcin precursor FeoB_N PF02421.18 OWF43337.1 - 0.076 12.5 0.3 5.2 6.6 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.21 OWF43337.1 - 0.078 12.4 0.2 0.51 9.8 0.1 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Sigma54_activat PF00158.26 OWF43337.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 OWF43337.1 - 0.16 11.7 1.8 7.8 6.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Abhydrolase_3 PF07859.13 OWF43338.1 - 3e-43 148.1 0.0 4.8e-31 108.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OWF43338.1 - 0.00018 20.5 0.2 0.00036 19.5 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 OWF43338.1 - 0.0014 17.6 0.1 0.0023 16.9 0.1 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OWF43338.1 - 0.0039 16.2 0.2 0.0096 15.0 0.2 1.6 1 1 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 OWF43338.1 - 0.12 11.6 0.0 0.41 9.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ras PF00071.22 OWF43339.1 - 7e-22 77.7 3.0 3.4e-21 75.5 3.0 1.9 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 OWF43339.1 - 2.4e-05 24.3 2.6 0.002 18.1 0.6 2.3 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 OWF43339.1 - 0.00017 21.8 0.8 0.0027 17.9 0.8 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 OWF43339.1 - 0.0071 16.0 0.2 0.05 13.3 0.2 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 OWF43339.1 - 0.033 13.7 1.8 0.2 11.2 1.8 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1480 PF07351.13 OWF43339.1 - 0.087 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) Ras PF00071.22 OWF43340.1 - 6.3e-24 84.4 1.0 2.7e-23 82.4 1.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF43340.1 - 3.3e-07 30.5 0.2 0.0047 17.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OWF43340.1 - 1.1e-05 25.4 0.2 0.041 13.8 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 OWF43340.1 - 0.00012 21.6 1.0 0.067 12.6 0.3 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 OWF43340.1 - 0.0062 16.1 0.7 0.079 12.5 0.7 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 OWF43340.1 - 0.019 14.7 0.2 0.068 12.9 0.1 1.9 1 1 0 2 2 2 0 AAA domain p450 PF00067.22 OWF43341.1 - 3e-31 108.7 0.1 3.5e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF43342.1 - 4.1e-100 335.7 0.1 4.7e-100 335.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 OWF43343.1 - 1.6e-21 75.8 0.2 1.6e-21 75.8 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4538) Cu-oxidase_2 PF07731.14 OWF43345.1 - 6.2e-40 136.1 11.4 5.1e-34 117.0 0.3 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 OWF43345.1 - 6.1e-37 126.3 4.4 6.3e-37 126.2 0.2 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OWF43345.1 - 4.4e-31 108.1 0.2 8.6e-28 97.5 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF43346.1 - 3.1e-38 130.6 13.8 4.2e-34 117.2 0.4 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 OWF43346.1 - 3.4e-36 123.8 0.2 3.4e-36 123.8 0.2 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 OWF43346.1 - 3.5e-32 111.7 0.4 5.3e-29 101.4 0.2 2.3 2 0 0 2 2 2 2 Multicopper oxidase Sulfotransfer_2 PF03567.14 OWF43347.1 - 2.1e-21 77.0 4.6 1.6e-18 67.6 0.5 3.0 1 1 1 2 2 2 1 Sulfotransferase family Ldl_recept_b PF00058.17 OWF43348.1 - 4.1e-17 62.4 1.0 3e-09 37.2 0.1 3.1 3 0 0 3 3 3 2 Low-density lipoprotein receptor repeat class B zf-C2H2_jaz PF12171.8 OWF43349.1 - 0.023 15.0 6.9 0.12 12.7 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF43349.1 - 0.032 14.6 3.1 0.33 11.3 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OWF43349.1 - 0.38 11.2 9.3 0.091 13.2 2.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 OWF43350.1 - 2.7e-18 66.0 26.6 2.7e-18 66.0 26.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PSI_PsaH PF03244.14 OWF43350.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI DUF4834 PF16118.5 OWF43350.1 - 0.19 12.7 0.1 7.6 7.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) MFS_1 PF07690.16 OWF43351.1 - 4.3e-15 55.5 46.1 4.3e-15 55.5 46.1 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PepSY_TM PF03929.16 OWF43351.1 - 0.0065 16.2 0.1 0.019 14.7 0.1 1.8 2 0 0 2 2 2 1 PepSY-associated TM region Syntaxin-18_N PF10496.9 OWF43352.1 - 0.064 13.5 0.4 0.064 13.5 0.4 3.4 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4209 PF13910.6 OWF43353.1 - 1.4e-25 89.3 0.0 4.1e-22 78.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Herpes_BLLF1 PF05109.13 OWF43353.1 - 0.16 9.9 62.1 0.28 9.1 27.5 2.1 1 1 1 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF948 PF06103.11 OWF43353.1 - 0.17 12.1 3.4 3.2 8.1 1.2 3.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MARVEL PF01284.23 OWF43356.1 - 0.0019 18.2 6.1 0.0048 16.9 6.1 1.6 1 1 0 1 1 1 1 Membrane-associating domain TatD_DNase PF01026.21 OWF43357.1 - 4.6e-24 85.2 0.0 5.4e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase LRR_8 PF13855.6 OWF43358.1 - 8.5e-13 47.9 18.0 1.1e-10 41.1 3.6 4.7 3 1 0 4 4 4 2 Leucine rich repeat TIR PF01582.20 OWF43358.1 - 2.1e-09 37.4 0.1 3.9e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF43358.1 - 3.8e-09 37.2 0.1 1.2e-08 35.6 0.1 1.8 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF43358.1 - 5.9e-08 32.9 21.1 0.00031 21.1 5.4 5.4 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF43358.1 - 1e-07 31.6 6.6 0.0038 16.7 1.8 3.5 3 0 0 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 OWF43358.1 - 0.0011 19.2 14.0 1.4 9.8 0.3 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat LRRNT PF01462.18 OWF43358.1 - 0.0095 15.6 3.7 0.0095 15.6 3.7 2.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 OWF43359.1 - 7.6e-16 57.6 22.8 1.3e-09 37.6 2.9 4.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 OWF43359.1 - 6.6e-07 29.0 7.9 0.014 14.9 2.2 3.1 2 1 0 3 3 3 2 Leucine-rich repeat TIR_2 PF13676.6 OWF43359.1 - 7.9e-07 29.7 0.1 2e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF43359.1 - 1.1e-06 28.9 25.0 0.0016 18.8 4.6 5.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF43359.1 - 3.5e-06 26.9 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.18 OWF43359.1 - 0.0025 17.4 3.4 0.0025 17.4 3.4 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain DUF4421 PF14391.6 OWF43359.1 - 0.0068 15.8 0.2 0.013 15.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4421) LRR_1 PF00560.33 OWF43359.1 - 0.58 10.9 19.5 7.6 7.5 0.7 6.7 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 OWF43360.1 - 6.4e-12 45.1 21.5 1e-09 38.0 4.3 4.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OWF43360.1 - 6.2e-07 29.7 25.3 0.00035 20.9 6.3 6.0 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 OWF43360.1 - 7.5e-07 29.8 0.1 2e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF43360.1 - 3e-06 27.1 0.0 7.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF43360.1 - 1.2e-05 24.9 9.4 0.061 12.8 0.0 3.6 2 1 1 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 OWF43360.1 - 0.0024 17.5 3.4 0.0024 17.5 3.4 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 OWF43360.1 - 0.065 13.8 20.8 4.1 8.3 0.1 6.7 7 0 0 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.25 OWF43362.1 - 3.9e-73 246.1 0.0 4.8e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF43362.1 - 1.2e-35 123.1 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OWF43362.1 - 1.4e-17 64.1 0.3 3.5e-17 62.8 0.1 1.8 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 OWF43362.1 - 4.2e-07 30.6 1.3 8.2e-07 29.6 1.3 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OWF43362.1 - 3.2e-06 26.7 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OWF43362.1 - 0.0052 16.4 0.6 0.091 12.4 0.2 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PH_11 PF15413.6 OWF43362.1 - 0.0072 16.7 1.3 0.072 13.5 0.3 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Haspin_kinase PF12330.8 OWF43362.1 - 0.056 12.4 0.6 0.095 11.6 0.6 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Adap_comp_sub PF00928.21 OWF43363.1 - 1.6e-55 188.3 0.7 2.1e-55 188.0 0.7 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OWF43363.1 - 0.00029 20.8 0.4 0.00049 20.1 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cob_adeno_trans PF01923.18 OWF43365.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase BRE PF06113.12 OWF43366.1 - 6.4e-115 383.4 0.1 7.4e-115 383.2 0.1 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.26 OWF43366.1 - 0.0087 15.7 5.0 1.3 8.7 0.2 2.5 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF43366.1 - 0.038 14.3 0.3 9.4 6.6 0.1 2.4 2 0 0 2 2 2 0 RWD domain DEAD PF00270.29 OWF43367.1 - 1.7e-39 135.4 0.2 3e-39 134.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF43367.1 - 3.9e-22 78.7 3.1 1.8e-21 76.5 0.0 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF43367.1 - 2.3e-06 27.7 0.3 5.4e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OWF43367.1 - 0.00026 19.8 1.3 0.0007 18.4 0.0 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain AAA_22 PF13401.6 OWF43367.1 - 0.0071 16.6 0.5 0.034 14.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain zf-C2H2 PF00096.26 OWF43368.1 - 2.5e-18 65.4 48.2 4.4e-05 23.7 1.1 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43368.1 - 2.1e-12 46.7 43.3 0.0019 18.9 1.6 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 OWF43368.1 - 3.8e-05 23.9 30.0 0.055 13.9 0.1 6.2 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OWF43368.1 - 7e-05 23.1 45.8 1.2 9.6 2.4 8.2 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF43368.1 - 0.00077 19.7 34.7 0.065 13.5 0.7 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF43368.1 - 0.0036 17.2 38.7 0.065 13.2 0.3 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf_UBZ PF18439.1 OWF43368.1 - 0.022 14.3 18.5 0.096 12.3 0.9 4.8 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 OWF43368.1 - 0.049 14.3 2.3 0.049 14.3 2.3 4.6 3 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 OWF43368.1 - 0.087 13.6 19.0 0.44 11.3 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon family ARS2 PF04959.13 OWF43368.1 - 6.5 7.1 8.5 0.24 11.7 2.0 2.0 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-MYST PF17772.1 OWF43368.1 - 7.7 6.2 17.2 1.1 8.9 0.1 4.4 3 1 1 4 4 4 0 MYST family zinc finger domain Porphobil_deam PF01379.20 OWF43369.1 - 2.4e-80 268.9 0.2 3.7e-80 268.2 0.0 1.4 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OWF43369.1 - 5.5e-16 58.7 1.1 4.6e-15 55.7 0.0 2.9 3 1 1 4 4 4 1 Porphobilinogen deaminase, C-terminal domain Globin PF00042.22 OWF43370.1 - 8.3e-11 42.4 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Globin PglD_N PF17836.1 OWF43370.1 - 0.085 13.5 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 PglD N-terminal domain Globin PF00042.22 OWF43371.1 - 7.2e-15 55.5 0.1 1.8e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Globin PMP22_Claudin PF00822.20 OWF43372.1 - 3.7e-11 43.2 9.0 4.7e-11 42.9 9.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF43372.1 - 7.3e-09 35.7 16.0 1.3e-07 31.6 16.0 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF43372.1 - 1.8e-05 24.7 13.2 3.9e-05 23.6 13.2 1.6 1 1 0 1 1 1 1 Tight junction protein, Claudin-like L_HMGIC_fpl PF10242.9 OWF43372.1 - 0.0004 20.6 12.4 0.0009 19.5 12.7 1.4 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein TMEM37 PF15108.6 OWF43372.1 - 0.014 15.3 9.9 0.02 14.7 6.3 2.1 1 1 1 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF4064 PF13273.6 OWF43372.1 - 2.2 8.6 8.5 15 5.9 5.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) DUF973 PF06157.11 OWF43372.1 - 5.8 5.9 6.7 6.7 5.7 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Ras PF00071.22 OWF43373.1 - 9.5e-40 135.8 0.0 1.3e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43373.1 - 6.9e-29 100.5 0.0 1.1e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43373.1 - 3.6e-12 46.1 0.0 4.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF43373.1 - 2e-06 27.4 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OWF43373.1 - 0.0001 22.2 0.2 0.028 14.2 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OWF43373.1 - 0.00018 21.0 0.0 0.00021 20.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF43373.1 - 0.00023 20.8 0.0 0.0021 17.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF43373.1 - 0.00075 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OWF43373.1 - 0.0043 16.8 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF43373.1 - 0.0079 16.5 0.0 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OWF43373.1 - 0.038 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OWF43373.1 - 0.063 13.2 0.0 6.2 6.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 OWF43373.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Methyltransf_3 PF01596.17 OWF43374.1 - 8.1e-41 139.5 0.0 1e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OWF43374.1 - 8.1e-05 23.6 0.0 0.00012 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF43374.1 - 0.00034 20.4 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 OWF43374.1 - 0.0063 16.2 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Peptidase_M99_m PF17130.4 OWF43375.1 - 0.00034 20.5 6.8 38 4.3 0.0 7.9 3 1 6 10 10 10 0 beta-barrel domain of carboxypeptidase M99 BBP2_2 PF10082.9 OWF43375.1 - 0.0044 15.9 0.1 0.87 8.3 0.0 2.9 1 1 1 3 3 3 1 Putative beta-barrel porin 2 Pentapeptide_3 PF13576.6 OWF43375.1 - 0.0073 16.4 0.2 1.7 8.9 0.0 4.0 4 1 0 4 4 4 1 Pentapeptide repeats (9 copies) DUF4077 PF13295.6 OWF43375.1 - 0.039 13.9 12.9 0.93 9.4 1.9 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4077) Utp12 PF04003.12 OWF43375.1 - 0.045 14.1 1.9 26 5.2 0.1 3.8 2 2 2 5 5 5 0 Dip2/Utp12 Family DUF1810 PF08837.11 OWF43375.1 - 0.2 11.5 1.3 24 4.7 0.0 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1810) DUF4452 PF14618.6 OWF43375.1 - 0.41 10.5 16.7 0.95 9.3 0.1 5.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4452) DUF2651 PF10852.8 OWF43375.1 - 0.77 10.4 25.8 13 6.5 1.5 6.6 1 1 6 7 7 7 0 Protein of unknown function (DUF2651) CPT_N PF16484.5 OWF43375.1 - 0.82 9.7 7.6 2.3e+02 1.9 0.0 5.6 3 3 6 10 10 10 0 Carnitine O-palmitoyltransferase N-terminus Ipi1_N PF12333.8 OWF43375.1 - 2.6 8.7 7.8 1e+02 3.5 0.0 6.1 4 4 2 7 7 7 0 Rix1 complex component involved in 60S ribosome maturation HicB_lk_antitox PF15919.5 OWF43375.1 - 5 7.3 11.8 11 6.2 0.2 3.9 1 1 3 4 4 4 0 HicB_like antitoxin of bacterial toxin-antitoxin system Methyltransf_3 PF01596.17 OWF43376.1 - 1.8e-42 144.9 0.1 2.3e-42 144.6 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OWF43376.1 - 6.7e-09 36.7 0.0 9.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF43376.1 - 3.4e-05 24.5 0.0 6.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF43376.1 - 0.0009 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 OWF43376.1 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF43376.1 - 0.015 15.9 0.0 0.028 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OWF43376.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UDPGT PF00201.18 OWF43377.1 - 2.2e-75 254.3 0.3 2.8e-75 254.0 0.3 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OWF43377.1 - 0.0004 20.4 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Antistasin PF02822.14 OWF43379.1 - 0.00023 21.7 9.5 0.00023 21.7 9.5 2.5 2 0 0 2 2 2 1 Antistasin family SRCR PF00530.18 OWF43380.1 - 7.7e-41 138.7 2.3 1.1e-16 61.1 0.1 3.5 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF43380.1 - 5.3e-14 52.5 2.4 3.4e-06 27.5 0.2 3.7 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF43380.1 - 1e-06 29.2 1.5 0.066 13.7 0.0 3.6 3 0 0 3 3 3 2 Hepsin, SRCR domain Beta_helix PF13229.6 OWF43380.1 - 1.1e-06 28.6 91.0 0.0032 17.3 20.8 8.9 6 2 1 8 8 8 4 Right handed beta helix region UL45 PF05473.12 OWF43380.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like BRCA2 PF00634.18 OWF43380.1 - 0.13 11.9 0.4 0.32 10.7 0.4 1.7 1 0 0 1 1 1 0 BRCA2 repeat SIT PF15330.6 OWF43380.1 - 7.9 7.0 5.4 5.5 7.5 0.0 3.0 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT 7tm_1 PF00001.21 OWF43381.1 - 1.2e-18 67.5 13.3 1.5e-18 67.1 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SfLAP PF11139.8 OWF43381.1 - 2 7.8 8.9 0.078 12.4 1.2 2.3 2 1 1 3 3 3 0 Sap, sulfolipid-1-addressing protein 7tm_1 PF00001.21 OWF43382.1 - 6.4e-23 81.4 14.2 8.9e-23 80.9 14.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Synaptobrevin PF00957.21 OWF43382.1 - 2.4 8.0 5.5 4.9 7.0 0.1 2.9 3 0 0 3 3 3 0 Synaptobrevin 7tm_1 PF00001.21 OWF43383.1 - 1.1e-19 70.8 21.4 1.1e-19 70.8 21.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Asp5 PF17000.5 OWF43383.1 - 0.068 13.3 2.3 0.092 12.9 0.1 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 Synaptobrevin PF00957.21 OWF43383.1 - 0.66 9.8 6.1 10 6.0 0.1 3.4 3 0 0 3 3 3 0 Synaptobrevin 7tm_1 PF00001.21 OWF43384.1 - 4e-20 72.2 23.1 4e-20 72.2 23.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 OWF43384.1 - 0.0067 16.4 2.7 0.0067 16.4 2.7 3.5 2 2 2 4 4 4 1 Caenorhabditis serpentine receptor-like protein, class xa Synaptobrevin PF00957.21 OWF43384.1 - 6.9 6.5 10.5 8.7 6.2 0.1 3.2 3 0 0 3 3 3 0 Synaptobrevin 7tm_1 PF00001.21 OWF43385.1 - 5.8e-05 22.5 3.7 6.2e-05 22.5 3.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 OWF43386.1 - 5.2e-19 68.6 21.9 5.2e-19 68.6 21.9 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 OWF43386.1 - 0.0068 16.4 2.5 0.0068 16.4 2.5 3.5 2 2 2 4 4 4 1 Caenorhabditis serpentine receptor-like protein, class xa Synaptobrevin PF00957.21 OWF43386.1 - 1.4 8.7 6.7 7.2 6.5 0.1 3.1 3 0 0 3 3 3 0 Synaptobrevin Ifi-6-16 PF06140.13 OWF43387.1 - 9.9e-24 83.1 33.4 1.4e-23 82.6 33.4 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF4686 PF15742.5 OWF43388.1 - 2.7e-27 95.9 68.1 2.7e-27 95.9 68.1 7.8 2 2 5 7 7 7 1 Domain of unknown function (DUF4686) GAS PF13851.6 OWF43388.1 - 7.1e-05 22.2 21.4 7.1e-05 22.2 21.4 13.2 5 4 8 13 13 13 4 Growth-arrest specific micro-tubule binding SOGA PF11365.8 OWF43388.1 - 0.075 14.2 0.3 0.075 14.2 0.3 17.5 3 3 14 18 18 18 0 Protein SOGA LRR_8 PF13855.6 OWF43389.1 - 1.1e-09 37.9 0.4 1.5e-06 27.8 1.6 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 OWF43389.1 - 9.7e-05 22.3 0.0 6.6 6.7 0.0 2.4 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF43389.1 - 0.087 13.3 5.5 0.17 12.3 4.5 2.2 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.23 OWF43390.1 - 7.5e-11 42.0 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OWF43390.1 - 4.9e-09 36.1 0.4 3.6e-08 33.3 0.4 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4083 PF13314.6 OWF43391.1 - 0.5 10.3 1.9 9.4 6.3 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) zf-B_box PF00643.24 OWF43392.1 - 6.2e-08 32.7 4.6 1.7e-07 31.3 4.6 1.8 1 0 0 1 1 1 1 B-box zinc finger SGL PF08450.12 OWF43392.1 - 0.026 14.1 1.0 0.55 9.8 0.1 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region FlaC_arch PF05377.11 OWF43392.1 - 0.037 14.4 1.5 0.037 14.4 1.5 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) 4HB_MCP_1 PF12729.7 OWF43392.1 - 0.083 12.4 2.0 0.17 11.4 2.0 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Reg_prop PF07494.11 OWF43392.1 - 0.083 13.2 1.2 72 4.1 0.0 4.1 3 0 0 3 3 3 0 Two component regulator propeller FlgN PF05130.12 OWF43392.1 - 0.15 12.6 1.6 0.31 11.5 0.2 2.1 1 1 1 2 2 2 0 FlgN protein zf-CSL PF05207.13 OWF43392.1 - 0.27 11.0 3.6 0.84 9.4 3.6 1.9 1 0 0 1 1 1 0 CSL zinc finger zf-met PF12874.7 OWF43393.1 - 2.1e-16 59.7 22.0 2.2e-08 34.2 0.7 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF43393.1 - 6e-09 36.0 20.0 6.8e-06 26.2 1.0 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF43393.1 - 0.012 15.9 14.7 0.18 12.2 2.3 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OWF43393.1 - 0.34 11.9 8.4 4.9 8.3 0.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger AKAP95 PF04988.12 OWF43393.1 - 1.2 9.4 15.5 1.5 9.0 0.9 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.12 OWF43393.1 - 2.4 8.0 14.9 4.3 7.2 1.1 3.5 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2_6 PF13912.6 OWF43393.1 - 4 7.5 5.3 9.5 6.4 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger PI3_PI4_kinase PF00454.27 OWF43394.1 - 4.1e-55 187.3 0.7 2.6e-54 184.7 0.7 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OWF43394.1 - 1.1e-54 184.7 0.9 1.9e-54 183.9 0.9 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 OWF43394.1 - 9.7e-31 105.3 0.1 2.6e-30 104.0 0.1 1.8 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.24 OWF43394.1 - 3.3e-21 75.7 0.0 8.6e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OWF43394.1 - 2.9e-20 72.4 0.4 1.2e-18 67.2 0.0 2.8 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain C2 PF00168.30 OWF43394.1 - 0.00052 20.3 0.1 0.0076 16.5 0.0 2.4 2 0 0 2 2 2 1 C2 domain DUF4135 PF13575.6 OWF43394.1 - 0.0016 17.9 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) MIEAP PF16026.5 OWF43395.1 - 0.00066 20.0 0.5 0.037 14.2 0.1 2.5 1 1 1 2 2 2 1 Mitochondria-eating protein MCPsignal PF00015.21 OWF43395.1 - 0.082 12.7 5.3 0.037 13.8 2.2 1.9 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CAP-ZIP_m PF15255.6 OWF43395.1 - 0.5 10.6 1.3 71 3.7 0.1 3.5 1 1 4 5 5 5 0 WASH complex subunit CAP-Z interacting, central region TraQ PF09679.10 OWF43395.1 - 0.62 10.0 14.0 8.2 6.4 0.5 4.5 1 1 4 5 5 5 0 Type-F conjugative transfer system pilin chaperone (TraQ) Phage-tail_1 PF09097.10 OWF43395.1 - 0.73 9.6 6.3 2.4 7.9 1.0 2.8 1 1 2 3 3 3 0 Baseplate structural protein, domain 1 Dicty_spore_N PF04562.12 OWF43396.1 - 0.019 15.7 10.3 1.1 9.9 10.5 2.2 1 1 0 1 1 1 0 Dictyostelium spore coat protein, N terminus DUF3432 PF11914.8 OWF43396.1 - 1.4 9.2 24.3 1.8e+04 -4.5 24.3 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Toxin_7 PF05980.12 OWF43396.1 - 3.4 8.0 32.2 40 4.6 5.3 5.4 1 1 5 6 6 6 0 Toxin 7 Pkinase_Tyr PF07714.17 OWF43397.1 - 1.3e-94 316.3 0.0 1.9e-94 315.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 OWF43397.1 - 6.1e-50 169.7 0.0 1.2e-49 168.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 OWF43397.1 - 6.2e-44 150.3 0.0 9.6e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 OWF43397.1 - 6.8e-25 87.2 7.9 8.2e-13 48.5 0.2 3.1 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.6 OWF43397.1 - 1.9e-22 79.9 0.0 4.3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.30 OWF43397.1 - 4.5e-18 65.5 0.1 1e-17 64.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF43397.1 - 7.1e-15 54.9 0.0 1.8e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ephrin_rec_like PF07699.13 OWF43397.1 - 7.6e-06 25.6 2.0 7.6e-06 25.6 2.0 2.7 2 1 1 3 3 3 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 OWF43397.1 - 1.6e-05 25.4 9.6 0.0032 18.0 0.3 2.9 1 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF43397.1 - 0.0061 16.8 2.2 1.2 9.5 0.4 3.7 3 1 1 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III Insulin_TMD PF17870.1 OWF43397.1 - 0.013 15.5 0.6 0.034 14.2 0.6 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Kdo PF06293.14 OWF43397.1 - 0.048 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_11 PF18831.1 OWF43397.1 - 0.065 12.8 1.4 0.13 11.8 1.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeat Haspin_kinase PF12330.8 OWF43397.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain F_actin_cap_B PF01115.17 OWF43399.1 - 1.2e-107 359.0 0.0 1.4e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 OWF43399.1 - 0.029 13.8 0.0 0.25 10.7 0.0 2.5 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Pkinase PF00069.25 OWF43400.1 - 8.8e-63 212.1 0.0 1.2e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF43400.1 - 1.2e-30 106.7 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 OWF43400.1 - 4.3e-14 52.2 0.0 1.1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.22 OWF43400.1 - 7.2e-14 51.4 8.9 1.5e-13 50.4 8.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OWF43400.1 - 1.7e-07 31.8 1.3 3.6e-07 30.8 1.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OWF43400.1 - 2.6e-05 23.7 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.16 OWF43400.1 - 0.0014 18.9 3.6 0.003 17.8 3.6 1.5 1 0 0 1 1 1 1 C1 domain Haspin_kinase PF12330.8 OWF43400.1 - 0.0038 16.2 0.1 0.0075 15.2 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF43400.1 - 0.079 12.3 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF43400.1 - 0.095 12.6 0.1 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family MgtE_N PF03448.17 OWF43401.1 - 4.2e-20 72.2 0.0 33 5.1 0.0 17.1 3 2 5 15 15 15 1 MgtE intracellular N domain Sfi1_C PF10638.9 OWF43401.1 - 7e-06 26.8 8.0 2.5e+02 2.5 0.0 15.0 14 0 0 14 14 14 0 Spindle body associated protein C-terminus LPD28 PF18843.1 OWF43401.1 - 0.00086 18.9 22.9 25 4.5 0.0 14.9 10 5 4 16 16 16 3 Large polyvalent protein associated domain 28 Cuticle_3 PF11018.8 OWF43401.1 - 0.46 10.7 42.6 19 5.4 0.4 12.4 1 1 9 13 13 13 0 Pupal cuticle protein C1 HALZ PF02183.18 OWF43403.1 - 0.00013 22.1 1.3 0.00027 21.1 0.2 2.0 1 1 1 2 2 2 1 Homeobox associated leucine zipper PI_PP_I PF18363.1 OWF43403.1 - 0.0072 16.5 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide phosphatase insertion domain TolA_bind_tri PF16331.5 OWF43403.1 - 0.011 15.8 2.1 0.04 14.0 2.2 1.8 2 1 0 2 2 2 0 TolA binding protein trimerisation Spectrin PF00435.21 OWF43403.1 - 0.017 15.6 1.9 0.027 14.9 1.9 1.2 1 0 0 1 1 1 0 Spectrin repeat Bap31_Bap29_C PF18035.1 OWF43403.1 - 0.02 14.9 2.4 0.034 14.1 2.4 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0184 PF03670.13 OWF43403.1 - 0.025 15.0 0.2 0.043 14.2 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) GIT_CC PF16559.5 OWF43403.1 - 0.025 14.4 4.4 0.057 13.3 4.5 1.5 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 OWF43403.1 - 0.025 14.4 1.8 0.042 13.6 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator MapZ_EC1 PF18041.1 OWF43403.1 - 0.049 13.9 1.4 0.076 13.2 1.4 1.2 1 0 0 1 1 1 0 MapZ extracellular domain 1 COG6 PF06419.11 OWF43403.1 - 0.077 11.2 0.3 0.1 10.8 0.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DHR10 PF18595.1 OWF43403.1 - 0.11 12.6 1.5 0.15 12.1 1.5 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain bZIP_1 PF00170.21 OWF43403.1 - 0.27 11.3 0.4 0.46 10.6 0.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OWF43403.1 - 0.8 9.8 2.1 1.5 8.9 1.5 1.5 1 1 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 OWF43403.1 - 0.81 10.2 4.4 0.4 11.1 0.8 1.6 1 1 0 1 1 1 0 Cell division protein ZapB ParB_C PF18064.1 OWF43404.1 - 1.5 9.0 10.3 25 5.1 0.2 4.8 2 2 4 6 6 6 0 Centromere-binding protein ParB C-terminal rve PF00665.26 OWF43405.1 - 0.12 12.5 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain 7tm_1 PF00001.21 OWF43406.1 - 6.7e-20 71.5 16.4 6.3e-14 51.9 7.6 2.4 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Mem_trans PF03547.18 OWF43406.1 - 2.2e-06 26.3 0.0 4.4e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein Orf78 PF06024.12 OWF43406.1 - 0.002 18.4 3.5 1.1 9.5 0.4 3.1 2 1 0 2 2 2 2 Orf78 (ac78) DUF2518 PF10726.9 OWF43406.1 - 2.9 7.6 5.5 0.42 10.3 0.8 1.9 2 0 0 2 2 2 0 Protein of function (DUF2518) RIFIN PF02009.16 OWF43406.1 - 8 6.3 9.2 1.8 8.4 0.1 2.6 1 1 1 3 3 3 0 Rifin AMA-1 PF02430.15 OWF43407.1 - 0.023 13.7 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Adeno_E3_CR2 PF02439.15 OWF43408.1 - 0.03 14.1 3.9 0.06 13.1 3.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MtrF PF09472.10 OWF43408.1 - 0.033 13.6 0.8 0.07 12.5 0.8 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Mid2 PF04478.12 OWF43408.1 - 0.11 12.4 1.0 0.18 11.6 1.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DDOST_48kD PF03345.14 OWF43409.1 - 3.9e-149 497.0 0.0 4.7e-149 496.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 OWF43409.1 - 0.0075 16.7 0.0 4.3 7.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4350) TPR_2 PF07719.17 OWF43410.1 - 9.1e-15 53.5 0.0 3.7e-05 23.5 0.3 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF43410.1 - 5.3e-11 41.8 0.0 0.00074 19.2 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF43410.1 - 9.4e-09 35.7 0.2 7.7e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF43410.1 - 2.7e-08 34.0 0.1 0.037 14.8 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF43410.1 - 5.1e-07 29.3 0.0 0.00011 21.8 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 OWF43410.1 - 2.6e-06 27.2 0.0 0.15 12.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF43410.1 - 7.5e-06 26.0 1.9 0.001 19.3 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat MAS20 PF02064.15 OWF43410.1 - 1.4e-05 25.2 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 MAS20 protein import receptor ANAPC3 PF12895.7 OWF43410.1 - 0.00016 21.8 0.2 0.00038 20.6 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OWF43410.1 - 0.002 18.4 0.2 0.67 10.3 0.9 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF43410.1 - 0.0055 16.6 0.1 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 OWF43410.1 - 0.095 11.9 0.0 6.3 5.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.12 OWF43410.1 - 0.1 12.6 0.0 6.1 6.9 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF627) COX1 PF00115.20 OWF43410.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I TPR_16 PF13432.6 OWF43410.1 - 0.18 12.5 0.1 2.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2897 PF11446.8 OWF43410.1 - 4 7.4 9.2 3.6 7.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) GARS_A PF01071.19 OWF43413.1 - 1.5e-77 259.8 0.2 1.1e-76 257.0 0.2 2.1 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 OWF43413.1 - 5.2e-59 199.0 0.1 8.6e-59 198.3 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 OWF43413.1 - 5.1e-36 123.4 0.4 1.9e-34 118.3 0.0 2.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 OWF43413.1 - 1.1e-29 103.6 0.0 3.3e-29 102.0 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 OWF43413.1 - 2.9e-23 82.0 0.7 1.1e-22 80.1 0.6 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 OWF43413.1 - 2.9e-16 59.9 2.5 1.4e-15 57.7 2.5 2.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_2 PF08442.10 OWF43413.1 - 0.00047 19.8 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 OWF43413.1 - 0.0032 17.1 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 OWF43413.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ADD_DNMT3 PF17980.1 OWF43413.1 - 0.2 11.7 0.7 0.44 10.6 0.7 1.5 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 MscS_TM PF12794.7 OWF43414.1 - 0.42 9.4 7.9 0.45 9.3 7.9 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF5585 PF17823.1 OWF43415.1 - 0.0063 15.5 3.8 0.0068 15.4 3.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5585) ATP-synt_G PF04718.15 OWF43416.1 - 1.6e-09 38.4 0.0 2.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit LRR_8 PF13855.6 OWF43417.1 - 4.5e-33 112.8 33.6 1.7e-07 30.9 5.4 7.1 2 2 7 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 OWF43417.1 - 4.6e-24 84.1 41.2 3.1e-06 27.4 5.1 8.8 2 2 7 10 10 10 10 Leucine Rich repeats (2 copies) COR PF16095.5 OWF43417.1 - 6.1e-19 68.6 0.1 1.8e-18 67.1 0.1 1.9 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF43417.1 - 5.3e-13 49.2 0.0 1.6e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF43417.1 - 3.1e-12 46.5 1.0 2.9e-11 43.4 0.5 3.0 3 0 0 3 3 3 1 Death domain Ras PF00071.22 OWF43417.1 - 1.7e-08 34.2 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Ras family LRR_5 PF13306.6 OWF43417.1 - 5.5e-06 26.4 0.5 0.0076 16.2 0.1 3.3 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF43417.1 - 5.2e-05 23.2 33.4 8.9 7.3 0.3 11.5 12 1 1 13 13 11 2 Leucine Rich Repeat Gtr1_RagA PF04670.12 OWF43417.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF43417.1 - 0.0023 18.0 0.0 0.0062 16.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF43417.1 - 0.014 14.8 0.0 0.043 13.3 0.0 1.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit LRR_6 PF13516.6 OWF43417.1 - 8.1 6.8 34.7 21 5.5 0.3 10.4 11 0 0 11 11 10 0 Leucine Rich repeat GON PF08685.11 OWF43419.1 - 7.5e-09 35.8 0.0 9.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 GON domain Lectin_C PF00059.21 OWF43420.1 - 5.5e-15 56.0 3.7 7.6e-15 55.6 3.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF43420.1 - 0.00015 21.5 1.4 0.00021 21.0 1.4 1.5 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Intimin_C PF07979.11 OWF43420.1 - 0.043 14.2 0.5 0.068 13.6 0.5 1.3 1 0 0 1 1 1 0 Intimin C-type lectin domain VWA PF00092.28 OWF43421.1 - 4.1e-118 391.9 23.8 1.1e-40 139.7 5.7 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF43421.1 - 2.9e-50 169.4 4.6 7e-16 58.8 0.1 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF43421.1 - 5.1e-25 88.2 1.1 7.4e-09 35.7 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Copine PF07002.16 OWF43421.1 - 9.1e-09 35.1 1.0 0.058 12.8 0.0 3.3 3 0 0 3 3 3 3 Copine VWA_CoxE PF05762.14 OWF43421.1 - 2.2e-07 30.5 2.1 0.011 15.1 0.0 3.3 3 1 0 3 3 3 2 VWA domain containing CoxE-like protein CutC PF03932.14 OWF43421.1 - 2.7e-07 30.3 5.9 0.0053 16.3 0.2 3.5 3 0 0 3 3 3 2 CutC family TssR PF17643.1 OWF43421.1 - 0.0014 16.7 0.8 0.0014 16.7 0.8 2.7 3 0 0 3 3 3 1 Type VI secretion system, TssR TmoB PF06234.12 OWF43421.1 - 0.042 13.9 1.0 6.9 6.8 0.0 3.5 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) DUF4429 PF14472.6 OWF43421.1 - 0.094 13.3 0.0 14 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4429) UPF0146 PF03686.13 OWF43421.1 - 0.098 12.5 0.8 11 5.9 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0146) ShK PF01549.24 OWF43421.1 - 2 9.0 9.5 3.6 8.2 9.5 1.4 1 0 0 1 1 1 0 ShK domain-like Mucin PF01456.17 OWF43421.1 - 4.5 7.3 49.8 0.44 10.5 39.7 2.9 2 0 0 2 2 2 0 Mucin-like glycoprotein USP8_interact PF08941.10 OWF43422.1 - 4.9e-88 293.6 4.3 6.6e-88 293.2 4.3 1.2 1 0 0 1 1 1 1 USP8 interacting zf-C3HC4_2 PF13923.6 OWF43422.1 - 3.7e-10 39.5 6.6 3.7e-10 39.5 6.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF43422.1 - 1.3e-08 34.5 5.5 1.3e-08 34.5 5.5 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF43422.1 - 6.9e-08 32.7 6.2 6.9e-08 32.7 6.2 2.2 2 0 0 2 2 1 1 Ring finger domain U-box PF04564.15 OWF43422.1 - 4.2e-06 26.8 0.1 1.4e-05 25.2 0.1 1.9 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.6 OWF43422.1 - 1.2e-05 25.0 3.0 1.2e-05 25.0 3.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF43422.1 - 1.3e-05 25.4 6.9 1.3e-05 25.4 6.9 2.7 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OWF43422.1 - 1.3e-05 25.2 6.3 7.6e-05 22.8 6.3 2.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF43422.1 - 2e-05 24.5 8.3 5.4e-05 23.1 8.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 OWF43422.1 - 2.6e-05 24.0 0.7 8.5e-05 22.4 0.7 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OWF43422.1 - 0.00028 20.8 2.8 0.00028 20.8 2.8 2.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-Nse PF11789.8 OWF43422.1 - 0.00054 19.7 3.3 0.0018 18.1 3.3 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 OWF43422.1 - 0.001 19.2 3.0 0.001 19.2 3.0 2.4 2 1 0 2 2 2 1 zinc RING finger of MSL2 Sina PF03145.16 OWF43422.1 - 0.0058 16.6 4.1 0.012 15.6 3.9 1.6 1 1 0 1 1 1 1 Seven in absentia protein family zf-ANAPC11 PF12861.7 OWF43422.1 - 0.0065 16.5 1.5 0.035 14.2 1.7 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TRAF_2 PF15965.5 OWF43422.1 - 0.07 13.6 9.6 0.2 12.2 6.2 3.3 2 1 1 3 3 3 0 TRAF-like zinc-finger Spc29 PF17082.5 OWF43422.1 - 0.15 11.9 1.3 0.3 10.9 1.3 1.5 1 1 0 1 1 1 0 Spindle Pole Component 29 zf-TRAF PF02176.18 OWF43422.1 - 0.22 12.2 8.7 1.7 9.4 2.2 3.4 2 1 1 3 3 3 0 TRAF-type zinc finger Prok-RING_4 PF14447.6 OWF43422.1 - 0.27 11.1 8.1 5.2 7.0 8.6 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SlyX PF04102.12 OWF43422.1 - 0.39 11.4 3.4 1 10.0 3.4 1.7 1 0 0 1 1 1 0 SlyX GAIN_A PF18619.1 OWF43422.1 - 0.76 10.0 3.9 1.2 9.4 0.3 2.7 3 0 0 3 3 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Zn_ribbon_17 PF17120.5 OWF43422.1 - 0.88 9.2 7.9 0.51 10.0 3.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type 7tm_1 PF00001.21 OWF43423.1 - 4.4e-50 170.5 16.2 5.5e-50 170.1 16.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF43423.1 - 7.3e-10 38.7 16.4 1.2e-09 37.9 16.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF43423.1 - 0.01 15.6 14.0 0.046 13.5 14.0 2.0 1 1 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 OWF43423.1 - 0.74 9.6 17.6 1.8 8.3 17.6 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 ASFV_J13L PF05568.11 OWF43423.1 - 0.95 9.2 3.7 3.9 7.2 0.5 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein Comm PF15957.5 OWF43423.1 - 2.4 8.5 7.3 2.3 8.6 0.5 3.2 3 0 0 3 3 3 0 Commissureless TMEM154 PF15102.6 OWF43423.1 - 6.8 6.6 5.6 0.94 9.4 1.4 1.7 2 0 0 2 2 2 0 TMEM154 protein family OATP PF03137.20 OWF43424.1 - 3.7e-161 537.1 20.1 5.6e-161 536.5 20.1 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF43424.1 - 2.5e-26 92.5 15.9 1.3e-19 70.3 9.4 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF43424.1 - 2.3e-05 24.4 3.8 2.3e-05 24.4 3.8 3.1 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF43424.1 - 0.16 12.0 8.7 0.046 13.7 3.4 2.5 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DUF2627 PF11118.8 OWF43424.1 - 0.24 12.0 2.9 20 5.9 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) SYS1 PF09801.9 OWF43424.1 - 3.2 7.9 9.5 4.8 7.3 1.8 2.6 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Neur_chan_memb PF02932.16 OWF43425.1 - 6.6e-18 65.6 15.5 1.8e-16 60.9 12.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF43425.1 - 1.5e-17 63.8 0.0 2.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain RRN3 PF05327.11 OWF43425.1 - 0.043 12.4 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2417 PF10329.9 OWF43425.1 - 0.61 9.5 7.1 1.2 8.5 7.1 1.6 1 1 0 1 1 1 0 Region of unknown function (DUF2417) ABC2_membrane_5 PF13346.6 OWF43425.1 - 1.2 8.7 11.6 0.22 11.0 7.1 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4149 PF13664.6 OWF43425.1 - 2.5 8.5 8.6 12 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) FMO-like PF00743.19 OWF43426.1 - 2.1e-68 231.1 0.1 6.1e-52 176.7 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF43426.1 - 8.2e-14 51.6 0.2 1.2e-10 41.2 0.1 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF43426.1 - 1.4e-11 44.2 0.0 4.6e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF43426.1 - 1.1e-06 28.5 0.1 0.4 10.2 0.2 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OWF43426.1 - 7.4e-06 26.0 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OWF43426.1 - 2.6e-05 23.5 0.0 0.0045 16.2 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OWF43426.1 - 0.00012 22.6 0.3 0.0051 17.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF43426.1 - 0.0005 20.3 0.0 0.0016 18.6 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Zip PF02535.22 OWF43428.1 - 5.8e-63 213.1 12.0 5.8e-63 213.1 12.0 4.3 3 1 0 3 3 3 1 ZIP Zinc transporter UMPH-1 PF05822.12 OWF43429.1 - 7.3e-92 307.3 1.2 1.2e-91 306.7 1.2 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 OWF43429.1 - 4.1e-05 24.1 0.0 7.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase A_thal_3526 PF09713.10 OWF43429.1 - 0.41 10.9 2.5 1.2 9.5 0.1 2.8 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) DUF1397 PF07165.11 OWF43431.1 - 8.6e-05 22.0 9.3 0.012 15.1 0.9 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF1397) Phage_gp49_66 PF13876.6 OWF43431.1 - 0.0045 17.3 0.1 0.24 11.7 0.0 2.5 2 0 0 2 2 2 1 Phage protein (N4 Gp49/phage Sf6 gene 66) family MtrF PF09472.10 OWF43431.1 - 0.11 11.9 0.3 0.38 10.2 0.3 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) HLH PF00010.26 OWF43432.1 - 2.7e-13 49.7 0.9 5.7e-13 48.6 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Crystall PF00030.19 OWF43433.1 - 3e-32 110.6 0.1 4e-18 65.4 0.1 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 OWF43433.1 - 0.00046 20.3 0.2 0.11 12.7 0.0 2.9 3 0 0 3 3 3 2 Interleukin-4 inducing immunoglobulin-binding domain Inhibitor_I36 PF03995.13 OWF43433.1 - 0.00047 20.0 3.0 0.15 12.0 0.1 3.3 3 1 1 4 4 4 2 Peptidase inhibitor family I36 Transglut_core PF01841.19 OWF43434.1 - 0.00016 22.1 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Endonuc-dimeris PF09124.10 OWF43434.1 - 0.14 12.3 0.1 0.43 10.8 0.1 1.8 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation PspB PF06667.12 OWF43435.1 - 0.016 15.2 0.7 0.46 10.6 0.1 2.2 2 0 0 2 2 2 0 Phage shock protein B zf-CCHC PF00098.23 OWF43435.1 - 0.034 14.2 1.1 0.059 13.5 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Tnp_22_trimer PF17489.2 OWF43435.1 - 0.052 13.5 0.6 0.27 11.2 0.2 2.1 2 0 0 2 2 2 0 L1 transposable element trimerization domain MetOD2 PF18548.1 OWF43435.1 - 0.098 12.8 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Metanogen output domain 2 AAA_5 PF07728.14 OWF43436.1 - 0.023 14.7 7.1 13 5.8 0.1 4.7 1 1 4 5 5 5 0 AAA domain (dynein-related subfamily) PY_rept_46 PF09689.10 OWF43436.1 - 0.034 14.7 25.4 1.6 9.4 0.9 5.5 1 1 5 6 6 6 0 Plasmodium yoelii repeat (PY_rept_46) BLF1 PF17752.1 OWF43436.1 - 0.11 11.8 1.9 0.97 8.7 0.2 2.2 1 1 1 2 2 2 0 Burkholderia lethal factor 1 VF530 PF09905.9 OWF43436.1 - 0.17 12.1 0.3 25 5.1 0.0 3.7 2 2 2 4 4 4 0 DNA-binding protein VF530 APS_kinase PF01583.20 OWF43436.1 - 0.86 9.5 4.1 4.5 7.1 0.1 3.2 1 1 2 4 4 4 0 Adenylylsulphate kinase PseudoU_synth_2 PF00849.22 OWF43436.1 - 4.5 7.3 6.0 12 5.9 0.1 3.9 2 2 1 3 3 3 0 RNA pseudouridylate synthase Cep57_CLD_2 PF14197.6 OWF43436.1 - 6.8 6.9 13.9 1.2 9.2 0.5 4.5 3 2 2 5 5 5 0 Centrosome localisation domain of PPC89 PY_rept_46 PF09689.10 OWF43437.1 - 0.0015 19.0 13.1 0.029 15.0 3.7 3.2 1 1 4 5 5 5 5 Plasmodium yoelii repeat (PY_rept_46) VF530 PF09905.9 OWF43437.1 - 0.031 14.5 0.0 4.9 7.4 0.0 2.3 1 1 1 2 2 2 0 DNA-binding protein VF530 Med9 PF07544.13 OWF43437.1 - 3.3 7.9 8.5 18 5.5 8.2 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PY_rept_46 PF09689.10 OWF43438.1 - 0.0084 16.7 9.1 0.5 11.0 1.0 3.1 1 1 2 3 3 3 2 Plasmodium yoelii repeat (PY_rept_46) PseudoU_synth_2 PF00849.22 OWF43438.1 - 1.5 8.8 5.3 33 4.5 0.0 3.6 1 1 2 3 3 3 0 RNA pseudouridylate synthase Ago_N_1 PF18351.1 OWF43439.1 - 0.032 14.7 1.5 0.91 10.0 0.7 2.6 1 1 2 3 3 3 0 Fungal Argonaute N-terminal domain AAA_5 PF07728.14 OWF43439.1 - 0.035 14.1 5.7 14 5.7 0.1 4.2 1 1 3 4 4 4 0 AAA domain (dynein-related subfamily) DUF4283 PF14111.6 OWF43439.1 - 0.075 12.6 0.2 1.8 8.1 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4283) CAP_assoc_N PF14504.6 OWF43439.1 - 0.23 11.2 10.2 0.091 12.5 1.9 2.4 1 1 1 2 2 2 0 CAP-associated N-terminal PY_rept_46 PF09689.10 OWF43439.1 - 4 8.1 30.4 10 6.8 4.5 5.7 2 1 4 6 6 6 0 Plasmodium yoelii repeat (PY_rept_46) Gemini_AC4_5_2 PF08464.10 OWF43440.1 - 0.0015 18.5 1.3 29 4.7 0.0 4.6 6 0 0 6 6 6 2 Geminivirus AC4/5 conserved region VF530 PF09905.9 OWF43440.1 - 0.062 13.5 0.1 8.2 6.7 0.0 2.6 1 1 1 2 2 2 0 DNA-binding protein VF530 PY_rept_46 PF09689.10 OWF43440.1 - 0.18 12.4 14.2 7.7 7.2 1.3 3.5 1 1 2 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) FoP_duplication PF13865.6 OWF43440.1 - 6.1 7.5 21.8 1.8 9.2 1.9 3.4 1 1 2 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 DSL PF01414.19 OWF43441.1 - 5.6e-17 61.8 9.0 1.4e-16 60.5 9.0 1.7 1 0 0 1 1 1 1 Delta serrate ligand MNNL PF07657.13 OWF43441.1 - 3.6e-10 39.7 1.4 8.7e-10 38.5 1.4 1.6 1 0 0 1 1 1 1 N terminus of Notch ligand Laminin_G_2 PF02210.24 OWF43441.1 - 8e-08 32.9 0.6 3.1e-07 31.0 0.6 2.1 1 0 0 1 1 1 1 Laminin G domain RHS PF03527.14 OWF43441.1 - 2.1e-05 24.2 1.7 2.6 7.9 0.1 6.0 6 0 0 6 6 6 2 RHS protein EphA2_TM PF14575.6 OWF43441.1 - 0.0011 19.8 1.0 0.45 11.4 0.1 2.6 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 OWF43441.1 - 0.049 13.2 0.2 0.17 11.5 0.2 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family MgtE_N PF03448.17 OWF43442.1 - 7.6e-05 23.3 8.2 0.24 12.0 0.2 5.1 2 2 2 4 4 4 2 MgtE intracellular N domain SRI PF08236.11 OWF43442.1 - 9.3e-05 22.5 35.0 2.3 8.4 2.0 7.6 1 1 5 6 6 6 1 SRI (Set2 Rpb1 interacting) domain GED PF02212.18 OWF43442.1 - 9.9e-05 22.4 12.7 4.5 7.5 0.0 6.2 2 2 4 7 7 7 2 Dynamin GTPase effector domain Sec15 PF04091.12 OWF43442.1 - 0.00011 21.7 3.3 6.3 6.1 0.0 4.4 2 2 1 4 4 4 1 Exocyst complex subunit Sec15-like FliG_N PF14842.6 OWF43442.1 - 0.0003 21.3 10.1 0.59 10.7 0.1 5.5 2 2 4 6 6 6 1 FliG N-terminal domain SHIRT PF18655.1 OWF43442.1 - 0.00052 20.5 40.0 16 6.2 0.1 9.2 1 1 5 7 7 7 0 SHIRT domain Cornifin PF02389.15 OWF43442.1 - 0.0021 18.3 28.5 3 8.1 4.0 3.5 2 1 1 3 3 3 2 Cornifin (SPRR) family YueH PF14166.6 OWF43442.1 - 0.011 15.6 12.5 10 6.1 0.0 6.2 3 2 1 6 6 6 0 YueH-like protein Nexin_C PF08628.12 OWF43442.1 - 0.04 14.5 2.1 13 6.4 0.0 4.2 2 2 2 4 4 4 0 Sorting nexin C terminal LuxT_C PF18285.1 OWF43442.1 - 0.075 13.6 1.5 47 4.6 0.1 5.3 2 2 5 7 7 7 0 Tetracycline repressor LuxT C-terminal domain RNA_GG_bind PF10258.9 OWF43442.1 - 0.12 12.4 9.2 15 5.7 0.1 5.7 2 2 3 6 6 6 0 PHAX RNA-binding domain DUF1411 PF07199.11 OWF43442.1 - 0.7 9.5 6.8 13 5.3 0.1 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1411) Trigger_C PF05698.14 OWF43442.1 - 2.7 8.0 19.5 17 5.4 0.5 5.4 2 2 4 6 6 6 0 Bacterial trigger factor protein (TF) C-terminus PP_kinase_N PF13089.6 OWF43442.1 - 4 7.8 19.6 3.8 7.9 0.4 4.8 2 2 3 5 5 5 0 Polyphosphate kinase N-terminal domain VPR PF00522.18 OWF43442.1 - 5.1 7.2 29.5 0.62 10.1 1.8 7.0 1 1 6 7 7 7 0 VPR/VPX protein CDC4_D PF16856.5 OWF43442.1 - 5.2 7.0 16.2 30 4.6 0.1 7.5 4 2 6 10 10 10 0 Cell division control protein 4 dimerisation domain U3snoRNP10 PF12397.8 OWF43442.1 - 6.1 7.2 14.7 1.8e+04 -8.2 14.7 6.5 1 1 0 1 1 0 0 U3 small nucleolar RNA-associated protein 10 PIN_5 PF08745.11 OWF43442.1 - 6.2 6.2 5.7 5.5 6.3 0.9 2.6 2 1 1 3 3 3 0 PINc domain ribonuclease GTP_EFTU PF00009.27 OWF43447.1 - 1.5e-48 164.9 0.1 2.5e-48 164.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OWF43447.1 - 1.6e-23 83.2 0.0 4e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 OWF43447.1 - 2.5e-15 56.5 0.1 6.5e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 OWF43447.1 - 3.5e-07 30.5 1.0 9.1e-07 29.2 1.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF43447.1 - 1.3e-06 28.4 0.1 0.00011 22.3 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 OWF43447.1 - 0.07 12.7 0.1 11 5.6 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 OWF43447.1 - 0.098 12.2 0.2 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Ras family Ham1p_like PF01725.16 OWF43448.1 - 1.4e-54 184.9 0.0 1.8e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Ham1 family FAM110_C PF14160.6 OWF43450.1 - 1.8e-18 67.7 4.1 1.8e-18 67.7 4.1 3.6 3 1 1 4 4 4 1 Centrosome-associated C terminus FAM110_N PF14161.6 OWF43450.1 - 2.8e-13 50.0 0.0 8.4e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Centrosome-associated N terminus Tap-RNA_bind PF09162.10 OWF43451.1 - 0.039 13.8 0.7 0.15 11.9 0.7 2.0 1 0 0 1 1 1 0 Tap, RNA-binding Cas3_C PF18395.1 OWF43451.1 - 7.7 7.1 7.0 1.6 9.3 0.7 3.3 2 2 1 3 3 3 0 Cas3 C-terminal domain DUF1394 PF07159.12 OWF43452.1 - 8.9e-141 468.5 1.9 1e-140 468.3 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.6 OWF43452.1 - 0.023 13.2 0.1 0.04 12.4 0.1 1.4 1 1 0 1 1 1 0 WASH complex subunit 7, N-terminal DUF742 PF05331.11 OWF43452.1 - 0.085 12.7 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF742) Phage_Coat_B PF05356.11 OWF43453.1 - 7.3e-08 32.2 82.9 57 3.7 0.4 26.9 1 1 28 30 30 30 24 Phage Coat protein B DUF478 PF04334.12 OWF43454.1 - 4.5e-06 26.6 8.6 9.7 6.3 0.0 9.0 1 1 9 11 11 11 2 Protein of unknown function (DUF478) RepL PF05732.11 OWF43454.1 - 8e-05 22.1 0.2 9.8 5.6 0.0 4.6 5 0 0 5 5 5 3 Firmicute plasmid replication protein (RepL) Bac_A_amyl_C PF18612.1 OWF43454.1 - 0.00018 21.2 5.2 61 3.5 0.0 9.3 15 0 0 15 15 15 0 Bacterial Alpha amylase C-terminal domain HCMVantigenic_N PF12154.8 OWF43454.1 - 0.0025 17.9 39.6 8 6.7 0.0 12.6 16 0 0 16 16 16 4 Glycoprotein B N-terminal antigenic domain of HCMV PLDc PF00614.22 OWF43454.1 - 0.05 13.8 7.3 46 4.4 0.2 5.6 4 1 0 4 4 4 0 Phospholipase D Active site motif Glyco_hydro_20 PF00728.22 OWF43454.1 - 0.052 12.9 0.5 45 3.3 0.0 4.7 4 2 1 6 6 6 0 Glycosyl hydrolase family 20, catalytic domain Telomere_res PF16684.5 OWF43454.1 - 0.44 10.0 2.1 83 2.5 0.0 4.5 4 1 0 5 5 5 0 Telomere resolvase NHR2 PF08788.11 OWF43454.1 - 3.8 7.3 20.1 2.4e+02 1.6 0.0 10.5 6 4 9 15 15 15 0 NHR2 domain like LuxQ-periplasm PF09308.10 OWF43455.1 - 0.022 14.3 2.4 6.7 6.1 0.1 2.8 1 1 2 3 3 3 0 LuxQ, periplasmic SufE PF02657.15 OWF43455.1 - 0.037 13.9 3.0 23 4.9 0.1 3.8 1 1 3 4 4 4 0 Fe-S metabolism associated domain Nucleoporin_FG PF13634.6 OWF43455.1 - 0.49 11.3 3.7 3.3 8.6 1.4 2.1 1 1 1 2 2 2 0 Nucleoporin FG repeat region FAM219A PF15260.6 OWF43455.1 - 1.7 9.1 9.9 30 5.0 1.6 3.3 1 1 2 3 3 3 0 Protein family FAM219A HLH PF00010.26 OWF43456.1 - 2.2e-12 46.7 2.5 2.8e-12 46.4 1.4 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Myc_N PF01056.18 OWF43456.1 - 1.6e-09 38.2 22.5 1.6e-05 25.0 0.6 4.2 1 1 3 4 4 4 3 Myc amino-terminal region COX5A PF02284.16 OWF43456.1 - 0.055 13.5 0.1 0.88 9.6 0.0 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase subunit Va SR-25 PF10500.9 OWF43456.1 - 0.13 11.9 10.6 0.25 10.9 10.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Patched PF02460.18 OWF43457.1 - 2.3e-136 456.0 14.5 2.9e-136 455.7 14.5 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF43457.1 - 5.3e-35 120.5 6.5 5.3e-35 120.5 6.5 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OWF43457.1 - 0.26 8.9 15.5 0.5 7.9 15.5 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.15 OWF43457.1 - 6.3 5.6 31.7 0.39 9.6 4.5 2.5 3 0 0 3 3 3 0 MMPL family ketoacyl-synt PF00109.26 OWF43458.1 - 1.3e-78 264.1 0.1 3.9e-78 262.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OWF43458.1 - 1.6e-58 197.6 0.0 3.7e-58 196.4 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 OWF43458.1 - 3.1e-40 138.6 0.0 7.2e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OWF43458.1 - 1.7e-37 128.0 0.0 8.5e-37 125.8 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 OWF43458.1 - 3.4e-33 115.2 0.0 5.4e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 OWF43458.1 - 1.4e-13 50.9 0.2 3.3e-13 49.8 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 OWF43458.1 - 4.2e-13 49.7 0.0 2.5e-11 44.0 0.0 3.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 OWF43458.1 - 8.2e-13 48.2 0.0 2.2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF43458.1 - 7.5e-11 42.0 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Condensation PF00668.20 OWF43458.1 - 4.7e-09 35.4 0.3 1.2e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 Condensation domain Thiolase_N PF00108.23 OWF43458.1 - 8.2e-06 25.4 0.3 2.1e-05 24.0 0.3 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain HECT PF00632.25 OWF43459.1 - 8.4e-11 41.9 2.2 1.7e-10 40.9 2.2 1.4 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 OWF43460.1 - 1.5e-16 60.8 1.4 4.5e-16 59.2 1.4 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_S24 PF00717.23 OWF43461.1 - 6.5e-10 38.8 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OWF43461.1 - 5.5e-05 23.0 0.1 0.0056 16.5 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 F5_F8_type_C PF00754.25 OWF43462.1 - 1e-19 70.9 0.2 1.7e-19 70.2 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain PAN_1 PF00024.26 OWF43462.1 - 0.0012 18.7 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF43462.1 - 0.053 13.4 0.2 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 PAN domain F5_F8_type_C PF00754.25 OWF43463.1 - 4.6e-19 68.8 0.1 9.4e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain PAN_1 PF00024.26 OWF43463.1 - 0.011 15.7 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 PAN domain Flagellin_C PF00700.21 OWF43465.1 - 0.79 10.1 6.5 20 5.6 0.2 5.1 2 1 5 8 8 8 0 Bacterial flagellin C-terminal helical region DUF4813 PF16072.5 OWF43465.1 - 9.1 5.8 19.1 14 5.3 1.2 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4813) F5_F8_type_C PF00754.25 OWF43466.1 - 2.3e-20 73.0 0.0 3.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain PAN_1 PF00024.26 OWF43466.1 - 3e-05 23.9 0.0 5.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF43466.1 - 0.0013 18.5 0.8 0.007 16.3 0.1 2.4 2 0 0 2 2 2 1 PAN domain Galactosyl_T PF01762.21 OWF43467.1 - 1.4e-41 142.5 0.2 2.1e-41 141.9 0.2 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF43467.1 - 0.089 12.2 0.1 0.21 11.0 0.1 1.7 1 1 0 1 1 1 0 Fringe-like OATP PF03137.20 OWF43468.1 - 3.9e-148 494.1 26.3 6.4e-148 493.4 26.3 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF43468.1 - 1.6e-26 93.1 32.0 2.9e-22 79.1 29.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF43468.1 - 3.4e-08 33.5 8.4 1.1e-07 31.9 8.4 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF43468.1 - 0.0041 17.1 6.9 0.0041 17.1 6.9 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain SabA_adhesion PF18304.1 OWF43468.1 - 0.0095 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 1 SabA N-terminal extracellular adhesion domain Lig_chan PF00060.26 OWF43468.1 - 0.032 14.1 1.5 0.44 10.4 0.0 2.8 3 0 0 3 3 3 0 Ligand-gated ion channel PI3K_p85B PF02192.16 OWF43469.1 - 0.063 13.0 29.4 31 4.4 2.5 7.7 1 1 3 4 4 4 0 PI3-kinase family, p85-binding domain Ints3 PF10189.9 OWF43469.1 - 8 5.7 21.9 4.7 6.4 2.8 3.9 1 1 3 4 4 4 0 Integrator complex subunit 3 Patched PF02460.18 OWF43470.1 - 3.6e-82 276.8 29.7 1.2e-51 175.8 1.3 2.6 3 0 0 3 3 3 2 Patched family NPC1_N PF16414.5 OWF43470.1 - 9.5e-69 231.6 16.7 1.5e-68 231.0 16.7 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 OWF43470.1 - 2.5e-56 189.8 3.2 2.5e-56 189.8 3.2 3.2 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OWF43470.1 - 2.2e-07 30.1 0.6 2.2e-07 30.1 0.6 2.4 2 1 0 2 2 2 1 MMPL family ACR_tran PF00873.19 OWF43470.1 - 1.5e-05 22.9 9.0 2.6e-05 22.1 9.0 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family RNase_PH PF01138.21 OWF43471.1 - 7.8e-34 117.0 0.0 1.2e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OWF43471.1 - 0.0034 17.4 0.1 0.009 16.0 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Aminotran_1_2 PF00155.21 OWF43472.1 - 2e-53 181.8 0.0 2.4e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OWF43472.1 - 2.4e-05 23.0 0.0 5.6e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OWF43472.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_21 PF05050.12 OWF43473.1 - 7.2e-12 45.7 0.1 1e-11 45.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain STT3 PF02516.14 OWF43474.1 - 9.7e-151 503.0 41.8 2.6e-146 488.4 37.1 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 OWF43474.1 - 3.8e-06 27.2 10.9 3.8e-06 27.2 10.9 3.0 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Holin_SPP1 PF04688.13 OWF43474.1 - 0.1 12.8 0.5 5.5 7.2 0.0 3.2 2 0 0 2 2 2 0 SPP1 phage holin AA_permease PF00324.21 OWF43475.1 - 8.1e-45 153.3 35.1 8.1e-45 153.3 35.1 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 OWF43475.1 - 1.4e-22 80.2 33.6 1.4e-22 80.2 33.6 1.8 2 0 0 2 2 2 1 Amino acid permease CABIT PF12736.7 OWF43476.1 - 0.00087 18.7 0.0 0.15 11.3 0.0 2.1 1 1 1 2 2 2 2 Cell-cycle sustaining, positive selection, 7tm_2 PF00002.24 OWF43477.1 - 4.6e-15 55.6 7.4 5.3e-15 55.4 7.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1702 PF08012.11 OWF43477.1 - 0.23 10.3 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Complex1_51K PF01512.17 OWF43478.1 - 6.2e-50 169.0 0.0 1.1e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OWF43478.1 - 1.9e-31 108.0 0.8 1.4e-30 105.1 0.1 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OWF43478.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 OWF43478.1 - 0.16 12.1 0.4 0.3 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Arm PF00514.23 OWF43479.1 - 5.4e-52 172.3 28.9 3.3e-10 39.6 0.1 12.5 13 1 0 13 13 13 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF43479.1 - 7.6e-13 48.7 5.4 0.0005 20.4 0.2 6.9 2 2 7 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 OWF43479.1 - 5e-12 46.0 12.8 2 9.0 0.0 9.2 10 0 0 10 10 9 3 HEAT-like repeat KAP PF05804.12 OWF43479.1 - 3.3e-11 42.1 3.2 5.2e-11 41.5 3.2 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT PF02985.22 OWF43479.1 - 6.6e-09 35.3 15.1 1.6 9.2 0.4 9.4 11 0 0 11 11 10 3 HEAT repeat V-ATPase_H_N PF03224.14 OWF43479.1 - 3.1e-07 30.0 9.5 0.00053 19.4 0.4 3.5 2 1 1 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.20 OWF43479.1 - 5.6e-07 28.5 12.5 1.5e-06 27.1 2.7 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 OWF43479.1 - 1.1e-06 28.8 6.9 0.015 15.4 0.8 4.5 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 OWF43479.1 - 5.2e-06 26.1 8.7 0.0019 17.7 0.6 3.0 1 1 2 3 3 3 2 Armadillo-like Vac14_Fab1_bd PF12755.7 OWF43479.1 - 0.00011 22.8 1.2 0.01 16.4 0.0 3.6 3 1 1 4 4 3 1 Vacuolar 14 Fab1-binding region WAPL PF07814.13 OWF43479.1 - 0.00029 19.8 2.4 0.029 13.2 0.7 2.9 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin DUF3361 PF11841.8 OWF43479.1 - 0.0065 16.4 7.0 1.8 8.5 0.1 4.1 2 1 2 4 4 4 2 Domain of unknown function (DUF3361) DotD PF16816.5 OWF43479.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 DotD protein UNC45-central PF11701.8 OWF43479.1 - 0.05 13.6 4.7 1.1 9.3 0.3 3.5 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central IBN_N PF03810.19 OWF43479.1 - 0.12 12.3 0.1 65 3.6 0.0 4.0 2 1 1 3 3 3 0 Importin-beta N-terminal domain ComGG PF14173.6 OWF43480.1 - 0.0013 19.1 3.2 67 4.0 0.0 5.5 1 1 7 8 8 8 0 ComG operon protein 7 PSRT PF07636.11 OWF43480.1 - 0.13 12.0 24.6 45 3.8 0.0 11.3 9 3 3 12 12 12 0 PSRT Fn_bind PF02986.14 OWF43480.1 - 0.22 11.3 18.6 44 3.9 0.3 8.3 4 2 6 10 10 10 0 Fibronectin binding repeat VIT PF08487.10 OWF43481.1 - 3.4e-27 94.9 0.0 7.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 OWF43481.1 - 2e-22 79.8 0.0 4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 OWF43481.1 - 5.1e-12 45.5 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 OWF43481.1 - 1.5e-10 41.7 0.0 5.2e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF43481.1 - 1.4e-08 35.2 0.0 3.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-H2C2_2 PF13465.6 OWF43482.1 - 1.3e-74 243.5 58.6 4.2e-10 39.6 0.7 11.0 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 OWF43482.1 - 1.9e-51 169.7 54.5 6.1e-06 26.4 1.4 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43482.1 - 6.2e-41 135.5 53.2 0.00088 19.9 0.1 10.3 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43482.1 - 1.7e-23 82.3 19.4 0.012 15.9 0.2 9.8 10 0 0 10 10 9 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF43482.1 - 1.6e-20 72.8 39.8 0.0042 17.4 0.3 10.4 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF43482.1 - 5.8e-12 45.3 58.3 0.0027 17.7 0.1 10.8 10 1 0 10 10 10 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF43482.1 - 1.5e-10 40.6 32.2 0.35 10.7 0.2 9.0 9 0 0 9 9 9 4 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 OWF43482.1 - 5.1e-07 29.9 21.6 0.0054 17.0 1.5 4.9 1 1 4 5 5 5 2 C2H2-type zinc ribbon DUF2180 PF09947.9 OWF43482.1 - 1.4e-05 24.9 21.4 1.2 9.1 0.4 6.3 2 1 4 6 6 6 3 Uncharacterized protein conserved in archaea (DUF2180) BolA PF01722.18 OWF43482.1 - 2.5e-05 24.4 6.9 0.31 11.4 2.0 4.7 1 1 1 3 3 3 2 BolA-like protein Zf_RING PF16744.5 OWF43482.1 - 7.6e-05 22.8 33.1 10 6.3 0.2 9.7 2 2 8 10 10 10 0 KIAA1045 RING finger GAGA PF09237.11 OWF43482.1 - 0.00011 22.0 13.3 0.43 10.4 0.1 6.6 2 2 4 7 7 7 1 GAGA factor C1_2 PF03107.16 OWF43482.1 - 0.00074 19.8 45.5 6.4 7.2 0.5 9.6 1 1 6 8 8 8 0 C1 domain zinc_ribbon_15 PF17032.5 OWF43482.1 - 0.0011 19.6 26.2 2.9 8.7 1.7 5.6 1 1 7 8 8 8 2 zinc-ribbon family DUF3268 PF11672.8 OWF43482.1 - 0.0015 18.8 25.9 0.056 13.8 0.3 5.3 4 1 0 5 5 5 2 zinc-finger-containing domain zf-C2H2_3rep PF18868.1 OWF43482.1 - 0.0042 17.8 34.9 0.0049 17.5 0.3 8.1 1 1 5 7 7 7 1 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 OWF43482.1 - 0.005 17.3 44.4 1 9.9 0.3 9.7 2 2 8 10 10 10 1 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 OWF43482.1 - 0.011 15.8 25.7 3.7 7.6 2.5 5.7 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 OWF43482.1 - 0.011 15.5 37.8 1.9 8.4 0.8 8.2 2 2 8 10 10 10 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_IE-1 PF05290.11 OWF43482.1 - 0.013 15.4 16.2 2.4 8.1 0.5 6.5 2 1 5 7 7 7 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_2 PF12756.7 OWF43482.1 - 0.013 15.8 41.0 3.2 8.1 0.8 9.0 1 1 5 8 8 8 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 OWF43482.1 - 0.015 15.5 39.9 0.019 15.2 1.3 7.3 2 2 5 8 8 8 0 TFIIH C1-like domain zf_UBZ PF18439.1 OWF43482.1 - 0.016 14.7 28.0 1.7 8.3 0.0 8.9 10 0 0 10 10 9 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 OWF43482.1 - 0.045 13.9 38.9 2.9 8.1 7.9 6.5 2 1 3 5 5 5 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 OWF43482.1 - 0.066 13.3 41.9 0.99 9.6 1.7 7.7 3 3 6 9 9 9 0 Zinc ribbon domain HTH_18 PF12833.7 OWF43482.1 - 0.13 12.6 0.6 18 5.7 0.0 4.0 4 0 0 4 4 3 0 Helix-turn-helix domain zf-C2HC_2 PF13913.6 OWF43482.1 - 0.16 11.9 33.2 0.18 11.7 0.2 9.1 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 OWF43482.1 - 0.77 9.4 20.9 12 5.5 0.3 7.4 5 3 3 8 8 8 0 MYST family zinc finger domain zf-AN1 PF01428.16 OWF43482.1 - 7.6 6.8 53.9 0.35 11.1 3.0 9.9 8 1 2 10 10 10 0 AN1-like Zinc finger 7tm_1 PF00001.21 OWF43483.1 - 1.4e-22 80.3 11.4 1.9e-22 79.9 11.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Alpha-amylase_C PF02806.18 OWF43484.1 - 1.1e-15 57.9 1.4 1.7e-15 57.2 0.1 2.1 2 1 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OWF43484.1 - 5.6e-13 49.2 0.0 1.4e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain COesterase PF00135.28 OWF43485.1 - 8.9e-133 443.8 0.1 1.1e-132 443.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF43485.1 - 2e-06 27.8 0.1 9e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF43485.1 - 0.0074 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family MBD PF01429.19 OWF43485.1 - 0.02 14.6 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 Methyl-CpG binding domain Y_Y_Y PF07495.13 OWF43486.1 - 2.2e-16 59.6 0.3 0.0022 17.9 0.0 5.2 5 0 0 5 5 5 4 Y_Y_Y domain REJ PF02010.15 OWF43486.1 - 2.9e-10 39.5 5.5 4.3e-06 25.8 1.3 3.1 1 1 1 2 2 2 2 REJ domain DUF4625 PF15418.6 OWF43486.1 - 4.7e-10 39.8 0.6 0.79 10.0 0.0 4.7 5 0 0 5 5 4 4 Domain of unknown function (DUF4625) Wzt_C PF14524.6 OWF43486.1 - 1.1e-07 32.0 0.2 2.7 8.0 0.0 5.1 5 0 0 5 5 5 3 Wzt C-terminal domain Big_9 PF17963.1 OWF43486.1 - 5.4e-07 30.3 16.2 0.076 13.8 0.1 5.4 5 0 0 5 5 5 3 Bacterial Ig domain DUF5013 PF16405.5 OWF43486.1 - 5.6e-07 29.9 3.2 4 7.7 0.0 5.3 3 2 1 5 5 5 2 Domain of unknown function (DUF5013) He_PIG PF05345.12 OWF43486.1 - 3.9e-05 23.7 5.9 5.7 7.2 0.0 5.4 5 0 0 5 5 5 2 Putative Ig domain PKD PF00801.20 OWF43486.1 - 5.2e-05 23.0 1.6 4.8 7.1 0.0 5.0 5 0 0 5 5 5 1 PKD domain DUF4998 PF16389.5 OWF43486.1 - 0.00018 21.2 2.7 2.2 7.8 0.0 5.0 5 0 0 5 5 5 2 Domain of unknown function DUF3324 PF11797.8 OWF43486.1 - 0.00048 20.1 1.2 2 8.4 0.1 4.8 4 1 0 4 4 4 1 Protein of unknown function C-terminal (DUF3324) EGF_2 PF07974.13 OWF43486.1 - 0.0087 16.4 5.6 0.0087 16.4 5.6 6.8 7 1 0 7 7 5 1 EGF-like domain ChitinaseA_N PF08329.10 OWF43486.1 - 0.023 14.3 0.1 4.8 6.8 0.0 3.4 3 1 0 3 3 3 0 Chitinase A, N-terminal domain Cadherin_5 PF17892.1 OWF43486.1 - 0.073 13.0 4.3 24 5.0 0.0 4.4 4 0 0 4 4 4 0 Cadherin-like domain DUF5011 PF16403.5 OWF43486.1 - 0.079 13.1 0.4 21 5.3 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) Zip PF02535.22 OWF43487.1 - 9e-61 205.9 14.3 9e-61 205.9 14.3 2.8 2 1 0 2 2 2 1 ZIP Zinc transporter ZIP4_domain PF18292.1 OWF43487.1 - 1.3e-07 31.7 2.0 0.0015 18.5 0.2 3.4 3 0 0 3 3 3 2 Zinc transporter ZIP4 domain SDA1 PF05285.12 OWF43487.1 - 0.0002 20.9 29.0 0.0003 20.3 29.0 1.3 1 0 0 1 1 1 1 SDA1 CPP1-like PF11833.8 OWF43487.1 - 0.59 9.8 2.8 0.59 9.8 0.2 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Mannosyl_trans4 PF15971.5 OWF43487.1 - 1.3 8.8 6.6 0.45 10.3 0.2 2.4 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase Chitin_synth_2 PF03142.15 OWF43488.1 - 1.5e-30 106.4 6.4 4.5e-27 94.9 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF43488.1 - 1.9e-14 54.1 7.4 6.3e-14 52.3 7.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF43488.1 - 9.9e-08 32.1 0.0 2.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OWF43488.1 - 0.00052 19.5 0.1 0.0024 17.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OWF43488.1 - 0.0038 17.0 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Kin17_mid PF10357.9 OWF43488.1 - 0.37 10.7 4.6 0.38 10.7 1.4 2.5 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein Chitin_synth_2 PF03142.15 OWF43489.1 - 4.4e-31 108.1 7.1 8.5e-28 97.3 0.5 2.6 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF43489.1 - 1.1e-13 51.6 3.2 4.5e-13 49.6 3.2 2.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF43489.1 - 5e-05 23.3 0.3 8.9e-05 22.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF43489.1 - 0.00086 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Bac_export_3 PF01313.19 OWF43489.1 - 0.5 10.3 9.2 0.83 9.6 3.1 3.4 2 0 0 2 2 2 0 Bacterial export proteins, family 3 Sulfatase PF00884.23 OWF43491.1 - 1.5e-55 188.7 0.5 2.2e-55 188.2 0.5 1.2 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 OWF43491.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) F5_F8_type_C PF00754.25 OWF43492.1 - 6e-16 58.7 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Lectin_C PF00059.21 OWF43492.1 - 1.5e-06 28.9 0.0 4e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF43492.1 - 5e-05 23.2 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 PAN domain Alpha-amylase PF00128.24 OWF43493.1 - 6.7e-55 187.0 0.5 9.7e-55 186.5 0.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 OWF43493.1 - 6.2e-18 64.1 0.7 1e-17 63.4 0.7 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus OppC_N PF12911.7 OWF43493.1 - 0.1 12.6 0.9 0.38 10.8 0.3 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Alpha-amylase PF00128.24 OWF43494.1 - 1.7e-66 225.1 5.2 2.9e-66 224.3 5.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 OWF43494.1 - 2.1e-16 59.2 1.5 4.4e-16 58.2 1.5 1.5 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus hDGE_amylase PF14701.6 OWF43494.1 - 0.00074 18.7 0.2 0.0012 18.1 0.2 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF4955 PF16315.5 OWF43494.1 - 0.15 12.2 0.5 0.39 10.9 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) Glyco_hydro_42C PF08533.10 OWF43494.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain FA_hydroxylase PF04116.13 OWF43495.1 - 1.3e-22 80.6 22.9 1.3e-22 80.6 22.9 2.7 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Na_H_antiporter PF03553.14 OWF43495.1 - 0.18 11.0 5.3 0.11 11.8 2.0 2.2 2 1 0 2 2 2 0 Na+/H+ antiporter family Terminase_2 PF03592.16 OWF43496.1 - 0.47 10.9 3.4 0.89 10.0 2.8 1.7 2 0 0 2 2 2 0 Terminase small subunit DHDPS PF00701.22 OWF43497.1 - 6.8e-51 172.7 0.0 7.8e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Acyl_transf_3 PF01757.22 OWF43498.1 - 9.2e-27 94.0 41.1 9.2e-27 94.0 41.1 1.5 2 0 0 2 2 2 1 Acyltransferase family DUF5381 PF17353.2 OWF43499.1 - 0.17 11.6 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5381) zf-C2H2_4 PF13894.6 OWF43500.1 - 8.3e-14 51.1 63.5 0.1 13.5 0.6 11.3 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF43500.1 - 2.2e-10 40.5 74.5 4e-08 33.3 0.4 9.8 12 0 0 12 12 12 6 Zinc-finger double domain zf-C2H2 PF00096.26 OWF43500.1 - 7.8e-10 38.7 71.7 0.001 19.4 3.5 11.3 11 0 0 11 11 11 5 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.12 OWF43500.1 - 0.0086 15.6 0.9 0.0086 15.6 0.9 5.0 6 0 0 6 6 6 1 TFIIB zinc-binding zf-H2C2_5 PF13909.6 OWF43500.1 - 0.0091 15.7 3.7 0.0091 15.7 3.7 8.3 9 0 0 9 9 9 3 C2H2-type zinc-finger domain zf-met PF12874.7 OWF43500.1 - 0.27 11.7 0.1 0.27 11.7 0.1 8.8 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-dskA_traR PF01258.17 OWF43500.1 - 7.9 6.5 9.4 39 4.3 0.9 3.9 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger EF-hand_1 PF00036.32 OWF43501.1 - 5.4e-14 50.6 12.2 0.002 17.5 0.6 6.5 4 3 3 7 7 7 6 EF hand EF-hand_6 PF13405.6 OWF43501.1 - 7.9e-12 44.1 18.6 0.003 17.4 1.0 7.0 4 3 3 7 7 7 4 EF-hand domain EF-hand_7 PF13499.6 OWF43501.1 - 6.8e-11 42.5 10.0 0.0002 21.8 4.0 4.9 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF43501.1 - 4.2e-10 38.7 10.3 0.011 15.2 1.2 5.4 3 2 2 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.9 OWF43501.1 - 7e-05 23.1 3.7 0.44 10.9 0.1 4.0 1 1 3 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF43501.1 - 9.3e-05 22.5 2.3 0.023 14.9 0.0 3.3 3 1 0 3 3 3 2 Dockerin type I domain EF-hand_8 PF13833.6 OWF43501.1 - 0.00019 21.2 7.3 0.2 11.5 0.3 4.0 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OWF43501.1 - 0.035 14.4 0.3 4.1 7.8 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain TIR PF01582.20 OWF43502.1 - 2.2e-13 50.4 0.0 2.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF43502.1 - 7.4e-09 36.2 0.0 1e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 TIR domain UPF0767 PF15990.5 OWF43502.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 UPF0767 family DpaA_N PF16924.5 OWF43504.1 - 0.043 13.9 0.1 0.081 13.0 0.1 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Trypsin PF00089.26 OWF43505.1 - 1.3e-59 201.7 1.4 1.5e-59 201.5 1.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF43505.1 - 2.9e-07 31.5 0.7 4.6e-07 30.8 0.7 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 OWF43505.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 RabGAP-TBC PF00566.18 OWF43506.1 - 1.5e-52 178.4 1.8 1.5e-52 178.4 1.8 3.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain eIF2_C PF09173.11 OWF43506.1 - 0.31 11.3 2.1 26 5.1 0.1 3.3 2 1 1 3 3 3 0 Initiation factor eIF2 gamma, C terminal Adhesin_P1_N PF18652.1 OWF43506.1 - 5.4 7.1 7.9 1.4 9.0 0.5 2.8 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain TSC22 PF01166.18 OWF43506.1 - 5.8 7.3 25.8 0.66 10.3 0.1 7.5 6 1 1 7 7 7 0 TSC-22/dip/bun family Rotamase PF00639.21 OWF43507.1 - 3.2e-22 79.3 0.0 4.1e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OWF43507.1 - 6.4e-21 75.1 0.0 8.2e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OWF43507.1 - 5.4e-09 36.0 0.2 5.4e-09 36.0 0.2 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 OWF43507.1 - 0.00063 20.6 0.0 0.00082 20.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 OWF43507.1 - 0.1 13.3 0.1 0.3 11.8 0.0 1.7 2 0 0 2 2 2 0 X8 domain DUF4347 PF14252.6 OWF43508.1 - 5.5e-05 23.1 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) Ank_2 PF12796.7 OWF43509.1 - 3e-05 24.5 0.1 6.4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) WD40 PF00400.32 OWF43510.1 - 1.2e-44 149.4 24.0 2.1e-10 41.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF43510.1 - 2e-24 85.7 1.6 5.3e-05 23.4 0.0 6.4 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF43510.1 - 6.2e-08 32.8 0.0 0.0055 16.6 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OWF43510.1 - 4.5e-07 28.9 0.1 0.0022 16.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OWF43510.1 - 9.1e-06 24.4 1.0 0.0031 16.1 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OWF43510.1 - 1.3e-05 24.4 3.4 1.2 8.0 0.0 4.9 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OWF43510.1 - 3.1e-05 23.5 0.1 0.79 9.0 0.0 3.3 3 1 1 4 4 4 2 WD40-like domain PHTB1_N PF14727.6 OWF43510.1 - 0.026 13.9 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 PTHB1 N-terminus Frtz PF11768.8 OWF43510.1 - 0.027 12.8 0.0 0.056 11.8 0.0 1.5 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz MMS1_N PF10433.9 OWF43510.1 - 0.075 11.7 0.0 0.76 8.3 0.0 2.3 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Chorion_S16 PF05836.12 OWF43510.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S16 PALB2_WD40 PF16756.5 OWF43510.1 - 0.11 11.3 0.8 9.8 5.0 0.0 2.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain BBS2_Mid PF14783.6 OWF43510.1 - 0.21 11.6 1.7 3.5 7.7 0.0 3.7 2 2 3 5 5 5 0 Ciliary BBSome complex subunit 2, middle region TPR_12 PF13424.6 OWF43511.1 - 2.2e-21 75.9 15.3 1.3e-07 31.8 0.0 6.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 OWF43511.1 - 1.3e-06 28.0 11.3 0.32 10.9 0.5 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF43511.1 - 5.5e-06 26.8 4.7 33 5.6 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OWF43511.1 - 9.1e-05 22.4 20.1 1.1 9.6 0.0 7.8 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF43511.1 - 0.00046 20.1 13.3 4.7 7.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF43511.1 - 0.0028 17.4 15.1 0.53 10.2 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat MRP-S28 PF10213.9 OWF43511.1 - 0.0038 17.6 0.9 0.0076 16.7 0.9 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein SPO22 PF08631.10 OWF43511.1 - 0.052 13.0 6.2 0.42 10.1 1.0 2.8 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_4 PF07721.14 OWF43511.1 - 0.091 13.4 3.9 5.5 7.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF43511.1 - 0.2 11.8 10.3 75 3.7 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat NAGLU_C PF12972.7 OWF43511.1 - 0.45 10.0 4.2 0.39 10.2 1.6 1.9 1 1 1 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain TPR_6 PF13174.6 OWF43511.1 - 6.8 7.6 12.9 18 6.2 0.0 6.2 8 1 0 8 8 7 0 Tetratricopeptide repeat DERM PF14704.6 OWF43513.1 - 9.6e-45 152.8 1.1 1.1e-44 152.5 1.1 1.0 1 0 0 1 1 1 1 Dermatopontin Ig_3 PF13927.6 OWF43514.1 - 1.6e-10 41.4 0.1 5.1e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF43514.1 - 1.9e-08 34.2 0.0 4.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF43514.1 - 4.2e-07 30.2 2.4 5e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Lectin_C PF00059.21 OWF43514.1 - 3.4e-06 27.8 1.2 5.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain ig PF00047.25 OWF43514.1 - 1e-05 25.6 0.0 4.6e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 OWF43514.1 - 0.013 15.6 0.0 0.088 13.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin V-set domain DUF4987 PF16377.5 OWF43514.1 - 0.026 14.7 0.1 0.052 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function PP2C_C PF07830.13 OWF43516.1 - 0.0023 18.3 1.8 39 4.8 0.0 5.3 1 1 3 5 5 5 1 Protein serine/threonine phosphatase 2C, C-terminal domain DNA_ligase_ZBD PF03119.16 OWF43516.1 - 0.11 12.6 2.0 0.32 11.1 2.0 1.9 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Regulator_TrmB PF11495.8 OWF43517.1 - 0.0079 15.4 0.4 1.1 8.3 0.1 2.2 1 1 1 2 2 2 2 Archaeal transcriptional regulator TrmB SAM_1 PF00536.30 OWF43517.1 - 0.013 15.9 0.4 35 5.0 0.0 3.8 1 1 2 4 4 4 0 SAM domain (Sterile alpha motif) Cyclin_N PF00134.23 OWF43518.1 - 6.8e-22 77.6 0.8 1.6e-21 76.3 0.4 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF716 PF04819.12 OWF43519.1 - 5.5e-25 87.6 7.3 1.3e-24 86.5 7.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF716) Med6 PF04934.14 OWF43520.1 - 3.4e-43 146.6 0.3 4.5e-43 146.3 0.3 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Ras PF00071.22 OWF43521.1 - 1.7e-42 144.8 0.0 2e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43521.1 - 3.1e-16 59.7 0.0 4.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43521.1 - 9e-05 22.0 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 OWF43521.1 - 0.024 14.9 0.1 1.3 9.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OWF43521.1 - 0.055 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OWF43521.1 - 0.1 12.3 0.3 0.32 10.7 0.1 1.9 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 OWF43522.1 - 6.9e-09 36.2 4.3 0.0038 18.0 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF43522.1 - 3.1e-06 27.4 0.0 1.3 9.3 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF43522.1 - 0.065 12.5 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Ras PF00071.22 OWF43523.1 - 5.1e-57 192.0 0.3 1.2e-56 190.8 0.3 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43523.1 - 2.2e-31 108.6 0.1 6.7e-31 107.0 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43523.1 - 4.2e-13 49.1 0.3 1.3e-12 47.6 0.2 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF43523.1 - 5.4e-06 25.9 0.1 1.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF43523.1 - 4.2e-05 23.6 0.0 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF43523.1 - 0.0048 16.5 0.3 0.016 14.8 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OWF43523.1 - 0.041 14.2 0.1 0.19 12.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF43523.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cript PF10235.9 OWF43524.1 - 2.3e-35 121.0 5.6 2.8e-35 120.8 5.6 1.1 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 OWF43524.1 - 0.00034 20.9 7.9 0.00048 20.4 7.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Tnp_zf-ribbon_2 PF13842.6 OWF43524.1 - 8.4 7.3 12.0 8.5 7.3 0.9 2.5 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Asparaginase PF00710.20 OWF43525.1 - 1.5e-23 83.4 0.0 1.8e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Asparaginase, N-terminal Minor_tail_Z PF06763.11 OWF43525.1 - 0.065 13.0 0.1 0.083 12.7 0.1 1.1 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) Pkinase PF00069.25 OWF43526.1 - 7.5e-31 107.4 0.0 2.4e-25 89.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.18 OWF43526.1 - 5.9e-13 48.7 0.7 1.3e-12 47.6 0.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.24 OWF43526.1 - 2.6e-11 43.5 1.1 2.6e-11 43.5 1.1 2.0 2 0 0 2 2 2 1 PX domain Pkinase_Tyr PF07714.17 OWF43526.1 - 1.3e-06 27.9 0.0 5.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF43526.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Arf PF00025.21 OWF43527.1 - 6.3e-18 64.8 0.1 7.8e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family BBS2_Mid PF14783.6 OWF43528.1 - 0.0001 22.3 0.8 0.94 9.5 0.0 3.3 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF5316 PF17247.2 OWF43528.1 - 0.0065 16.5 0.2 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5316) VCBS PF13517.6 OWF43528.1 - 0.02 15.5 1.4 0.05 14.2 0.3 2.3 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella fn3_2 PF16893.5 OWF43528.1 - 0.11 12.6 0.0 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain FG-GAP PF01839.23 OWF43528.1 - 0.14 12.3 1.6 0.99 9.6 0.2 2.5 2 0 0 2 2 2 0 FG-GAP repeat EF-hand_1 PF00036.32 OWF43529.1 - 3.7e-26 88.7 11.5 3.1e-07 29.5 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF43529.1 - 1.3e-24 86.4 8.6 3.1e-12 46.8 1.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF43529.1 - 9.3e-24 81.3 9.3 3.9e-07 29.5 0.3 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF43529.1 - 1.8e-18 65.1 10.2 1.8e-05 24.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF43529.1 - 1.1e-16 60.4 11.6 4.3e-11 42.5 1.1 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 OWF43529.1 - 4.2e-09 36.6 0.2 2.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF43529.1 - 4.4e-09 36.6 2.0 0.00043 20.6 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF43529.1 - 0.00074 20.4 1.0 1.5 9.8 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain CtsR_C PF17727.1 OWF43529.1 - 0.0012 18.9 0.9 2.2 8.5 0.0 3.7 3 1 1 4 4 4 1 CtsR C-terminal dimerization domain EF-hand_4 PF12763.7 OWF43529.1 - 0.0012 18.7 3.7 0.019 14.9 0.4 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF1456 PF07308.13 OWF43529.1 - 0.0036 17.6 0.7 0.33 11.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1456) EF-hand_14 PF17959.1 OWF43529.1 - 0.042 14.2 0.5 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain Ccdc124 PF06244.12 OWF43529.1 - 0.047 14.2 0.8 0.12 12.9 0.0 2.0 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 EF-hand_10 PF14788.6 OWF43529.1 - 0.059 13.2 8.3 0.43 10.5 0.5 3.2 2 1 1 3 3 3 0 EF hand NPM1-C PF16276.5 OWF43529.1 - 0.1 12.6 0.1 0.32 11.0 0.1 1.8 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain DUF3349 PF11829.8 OWF43529.1 - 0.13 13.1 0.2 11 6.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) SIX1_SD PF16878.5 OWF43531.1 - 6.4e-49 165.1 0.1 1.4e-48 164.0 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 OWF43531.1 - 3e-14 52.6 0.6 1.1e-13 50.8 0.2 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF43531.1 - 1.4e-12 47.3 0.2 3.3e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OWF43531.1 - 0.026 14.0 0.1 0.079 12.4 0.0 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 OWF43531.1 - 0.032 14.3 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix SIX1_SD PF16878.5 OWF43532.1 - 5e-48 162.2 0.4 5.7e-47 158.8 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 OWF43532.1 - 1e-12 47.7 3.8 2.1e-12 46.7 1.5 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF43532.1 - 1.1e-10 41.3 1.2 2.9e-10 39.9 1.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 OWF43532.1 - 0.024 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.8 OWF43532.1 - 0.064 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3043 PF11241.8 OWF43532.1 - 0.11 12.5 2.0 0.22 11.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DFRP_C PF16543.5 OWF43532.1 - 0.16 12.5 1.2 0.49 10.9 1.2 1.8 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 FYDLN_acid PF09538.10 OWF43532.1 - 0.19 12.4 4.3 0.4 11.4 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) EF-hand_6 PF13405.6 OWF43533.1 - 0.00046 19.9 0.1 0.00092 19.0 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OWF43533.1 - 0.0079 16.6 0.4 0.018 15.5 0.1 1.6 1 1 1 2 2 2 1 EF-hand domain pair Cupin_4 PF08007.12 OWF43534.1 - 4.4e-68 230.1 0.0 7.6e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OWF43534.1 - 2.1e-08 34.2 2.0 3.2e-06 27.1 2.0 3.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 OWF43534.1 - 2.8e-05 23.7 0.0 0.0005 19.7 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OWF43534.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Cupin Longin PF13774.6 OWF43535.1 - 2e-20 72.6 0.2 5.5e-20 71.2 0.2 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain Peptidase_U4 PF03419.13 OWF43535.1 - 0.071 12.4 2.1 0.12 11.6 2.1 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Shisa PF13908.6 OWF43536.1 - 8.7e-05 22.8 0.1 0.00013 22.2 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Cadherin_C_2 PF16492.5 OWF43536.1 - 0.003 18.3 0.3 0.064 14.0 0.0 2.3 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 OWF43536.1 - 0.0069 17.2 0.1 0.013 16.3 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.11 OWF43536.1 - 0.032 14.2 2.7 11 6.1 3.5 2.3 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein Podoplanin PF05808.11 OWF43536.1 - 0.045 13.9 0.3 0.082 13.0 0.3 1.4 1 0 0 1 1 1 0 Podoplanin SCIMP PF15050.6 OWF43536.1 - 0.12 12.8 0.2 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 SCIMP protein DUF4006 PF13179.6 OWF43536.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Prominin PF05478.11 OWF43536.1 - 0.15 10.0 1.4 0.2 9.6 1.4 1.0 1 0 0 1 1 1 0 Prominin TraL PF07178.11 OWF43536.1 - 0.18 12.3 0.8 0.61 10.6 1.0 1.7 2 0 0 2 2 2 0 TraL protein Adeno_E3_CR2 PF02439.15 OWF43536.1 - 1.2 8.9 12.6 2.4 8.0 12.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMIE PF16038.5 OWF43536.1 - 3.7 7.5 8.4 7.1 6.5 8.4 1.4 1 0 0 1 1 1 0 TMIE protein Ras PF00071.22 OWF43537.1 - 7.5e-67 224.0 1.0 8.7e-67 223.8 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43537.1 - 5.1e-37 126.7 0.1 8.8e-37 126.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43537.1 - 4.1e-18 65.4 0.2 5.3e-18 65.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF43537.1 - 6.2e-06 25.8 0.1 9.5e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF43537.1 - 8.6e-06 25.8 1.0 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OWF43537.1 - 9e-06 25.2 0.1 1.1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF43537.1 - 2.2e-05 24.5 0.1 3.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF43537.1 - 5.8e-05 22.7 0.3 0.00018 21.1 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 OWF43537.1 - 0.0073 16.7 0.0 0.19 12.2 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF43537.1 - 0.024 15.0 0.0 0.031 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OWF43537.1 - 0.028 14.2 0.1 0.88 9.3 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OWF43537.1 - 0.032 14.5 0.0 0.085 13.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF43537.1 - 0.035 13.6 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 OWF43537.1 - 0.042 13.1 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 OWF43537.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF43537.1 - 0.056 14.0 0.1 0.088 13.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OWF43537.1 - 0.058 13.4 0.1 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OWF43537.1 - 0.062 12.7 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OWF43537.1 - 0.07 12.6 0.1 0.37 10.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B LANC_like PF05147.13 OWF43537.1 - 0.084 11.4 0.1 0.17 10.4 0.0 1.5 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein Fcf1 PF04900.12 OWF43538.1 - 3.4e-39 133.2 2.3 6.6e-39 132.3 2.3 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OWF43538.1 - 4.1e-12 46.4 0.0 6.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 PIN like domain DUF5066 PF16728.5 OWF43538.1 - 0.039 13.3 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) LRR_6 PF13516.6 OWF43539.1 - 1.5e-23 80.8 9.2 0.0046 16.9 0.0 9.4 10 0 0 10 10 10 8 Leucine Rich repeat LRR_1 PF00560.33 OWF43539.1 - 7.9e-09 34.9 0.0 22 6.1 0.0 7.3 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 OWF43539.1 - 8.1e-08 32.5 3.7 0.074 13.5 0.1 4.7 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF43539.1 - 4.6e-05 23.1 8.3 0.88 9.4 3.3 5.4 4 1 0 4 4 4 2 Leucine rich repeat EF-hand_7 PF13499.6 OWF43539.1 - 0.0043 17.5 0.4 0.021 15.3 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain pair Pentapeptide_4 PF13599.6 OWF43540.1 - 5.4e-16 58.5 23.6 0.00063 19.9 2.4 4.3 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) SERTA PF06031.13 OWF43540.1 - 3.2e-10 39.5 45.6 1.6e+02 2.1 0.0 21.2 23 0 0 23 23 23 0 SERTA motif MecA PF05389.12 OWF43540.1 - 0.00012 21.8 46.4 1.7 8.2 2.1 6.0 1 1 7 8 8 8 8 Negative regulator of genetic competence (MecA) DUF3683 PF12447.8 OWF43540.1 - 0.0013 18.8 35.1 4.8 7.3 3.2 5.4 1 1 2 3 3 3 2 Protein of unknown function (DUF3683) TIP120 PF08623.10 OWF43540.1 - 0.011 15.5 49.8 4.4 7.0 6.5 4.9 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Adenine_glyco PF03352.13 OWF43540.1 - 0.038 13.8 37.2 1.7 8.4 9.3 3.1 1 1 2 3 3 3 0 Methyladenine glycosylase SapC PF07277.11 OWF43540.1 - 0.5 9.9 46.2 8.1 6.0 5.7 4.6 1 1 4 5 5 5 0 SapC NRBF2_MIT PF17169.4 OWF43540.1 - 0.96 9.7 37.4 24 5.3 4.3 5.6 1 1 5 6 6 6 0 MIT domain of nuclear receptor-binding factor 2 RTT107_BRCT_6 PF16771.5 OWF43540.1 - 2.4 8.3 49.6 1.8e+04 -29.5 49.6 5.8 1 1 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain ArAE_1_C PF11728.8 OWF43540.1 - 8.9 6.3 69.7 29 4.6 14.1 5.4 1 1 5 6 6 6 0 Putative aromatic acid exporter C-terminal domain bZIP_1 PF00170.21 OWF43541.1 - 1.9e-05 24.7 8.7 3.2e-05 23.9 8.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF43541.1 - 9.8e-05 22.4 4.9 0.00017 21.6 4.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF43541.1 - 0.00024 21.5 7.5 0.00041 20.8 7.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor AROS PF15684.5 OWF43541.1 - 0.11 13.1 5.1 0.19 12.3 5.1 1.3 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 bZIP_2 PF07716.15 OWF43542.1 - 5.1e-06 26.5 17.1 9.3e-06 25.6 17.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF43542.1 - 6.5e-05 22.9 20.4 0.00011 22.3 20.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF43542.1 - 0.0015 19.0 17.7 0.0015 19.0 17.7 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor DUF4337 PF14235.6 OWF43542.1 - 0.013 15.6 1.9 0.022 14.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LAM_C PF12544.8 OWF43542.1 - 0.57 10.4 4.0 1 9.6 3.8 1.6 1 1 0 1 1 1 0 Lysine-2,3-aminomutase Bin3 PF06859.12 OWF43542.1 - 0.66 10.6 4.4 1 10.0 4.3 1.4 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) DUF2828 PF11443.8 OWF43542.1 - 0.72 7.9 6.1 0.9 7.6 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FH2 PF02181.23 OWF43543.1 - 4.8e-104 348.4 13.1 4.8e-104 348.4 13.1 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OWF43543.1 - 3.4e-55 186.7 1.2 3.4e-55 186.7 1.2 3.7 4 0 0 4 4 4 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OWF43543.1 - 2.1e-46 157.9 0.1 2.1e-46 157.9 0.1 3.4 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain UPF0242 PF06785.11 OWF43543.1 - 0.0074 16.4 8.1 0.0074 16.4 8.1 3.7 3 1 0 3 3 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF3361 PF11841.8 OWF43543.1 - 0.014 15.3 1.6 0.024 14.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) MscS_porin PF12795.7 OWF43543.1 - 0.019 14.5 20.0 0.072 12.6 10.1 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain zf-C2H2_2 PF12756.7 OWF43543.1 - 0.5 10.7 7.5 0.32 11.4 2.4 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF948 PF06103.11 OWF43543.1 - 2.2 8.6 8.9 9.5 6.6 5.0 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HBS1_N PF08938.10 OWF43543.1 - 2.4 8.5 8.9 15 6.0 6.2 3.5 2 1 0 2 2 2 0 HBS1 N-terminus DNA_pack_N PF02500.15 OWF43543.1 - 5.7 6.7 9.5 0.42 10.4 0.1 3.0 2 1 1 3 3 3 0 Probable DNA packing protein, N-terminus DUF4599 PF15371.6 OWF43543.1 - 7.1 7.2 6.5 14 6.3 1.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4599) Kinesin PF00225.23 OWF43544.1 - 8.2e-100 334.0 0.6 2e-99 332.7 0.6 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF43544.1 - 8.4e-27 93.9 0.2 2.5e-26 92.4 0.2 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 OWF43544.1 - 0.078 13.3 0.1 0.82 10.0 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain DUF1192 PF06698.11 OWF43544.1 - 0.11 12.6 2.3 17 5.6 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF5104 PF17117.5 OWF43544.1 - 0.16 12.4 1.2 0.7 10.4 1.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) TcpS PF17456.2 OWF43544.1 - 3 7.9 6.7 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S UBX PF00789.20 OWF43545.1 - 1.7e-06 28.1 24.7 17 5.7 0.2 10.2 1 1 6 7 7 7 2 UBX domain DUF1134 PF06577.12 OWF43545.1 - 0.38 10.5 33.9 6.1 6.6 2.3 8.5 1 1 11 12 12 12 0 Protein of unknown function (DUF1134) Xol-1_N PF09108.10 OWF43545.1 - 0.38 10.6 27.6 23 4.8 0.3 8.3 1 1 6 7 7 7 0 Switch protein XOL-1, N-terminal WHH PF14414.6 OWF43545.1 - 1.6 8.7 6.0 1.4e+02 2.4 0.4 5.2 4 2 0 4 4 4 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH IMP2_N PF18590.1 OWF43545.1 - 4.3 8.0 48.7 4.2 8.0 0.5 10.5 1 1 10 12 12 12 0 Immune Mapped Protein 2 (IMP2) N-terminal domain GTP_EFTU PF00009.27 OWF43546.1 - 9.4e-27 93.8 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OWF43546.1 - 1.6e-08 34.8 0.5 4.4e-08 33.4 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 OWF43546.1 - 2.3e-05 24.7 0.1 6.1e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Dynamin_N PF00350.23 OWF43546.1 - 0.0007 19.7 0.1 0.58 10.2 0.0 2.6 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 OWF43546.1 - 0.0011 19.1 0.2 0.0055 16.8 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF43546.1 - 0.0011 18.9 0.4 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OWF43546.1 - 0.034 13.7 0.6 13 5.3 0.1 3.1 2 1 0 2 2 2 0 Ferrous iron transport protein B Lectin_C PF00059.21 OWF43547.1 - 2e-13 51.0 3.6 6.5e-13 49.4 3.6 1.9 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF43547.1 - 0.00049 20.0 6.7 0.00049 20.0 6.7 2.2 2 0 0 2 2 2 1 PAN domain Dpy-30 PF05186.13 OWF43548.1 - 2.4e-20 72.0 0.4 3.2e-20 71.5 0.4 1.2 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_L14 PF00238.19 OWF43549.1 - 3.2e-17 62.8 0.3 1.4e-16 60.6 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e DUF4537 PF15057.6 OWF43549.1 - 0.077 13.0 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) IL17 PF06083.11 OWF43550.1 - 1.9e-12 47.4 0.4 3e-12 46.9 0.4 1.3 1 0 0 1 1 1 1 Interleukin-17 BRCA-2_helical PF09169.10 OWF43551.1 - 4.3 6.9 3.8 1.5e+02 2.0 0.0 4.4 2 2 3 5 5 5 0 BRCA2, helical SeleniumBinding PF11524.8 OWF43552.1 - 0.0065 16.9 0.9 1.5e+02 2.9 0.0 5.4 4 2 3 7 7 7 0 Selenium binding protein FA_FANCE PF11510.8 OWF43552.1 - 0.04 13.3 0.1 7.8 5.8 0.0 3.6 3 1 2 5 5 5 0 Fanconi Anaemia group E protein FANCE AbiEi_3_N PF17194.4 OWF43553.1 - 4.8e-05 23.3 5.0 0.76 9.8 0.3 3.2 1 1 2 3 3 3 3 Transcriptional regulator, AbiEi antitoxin N-terminal domain Tmemb_170 PF10190.9 OWF43553.1 - 0.0048 17.2 3.3 0.67 10.3 0.5 2.2 1 1 1 2 2 2 2 Putative transmembrane protein 170 GerPB PF10803.8 OWF43553.1 - 0.048 13.7 2.6 23 5.2 0.5 3.8 1 1 2 3 3 3 0 Spore germination GerPB NCBP3 PF10309.9 OWF43553.1 - 0.55 10.1 1.1 28 4.7 0.0 2.8 1 1 2 3 3 3 0 Nuclear cap-binding protein subunit 3 zinc_ribbon_6 PF14599.6 OWF43554.1 - 0.23 11.5 4.0 0.59 10.2 4.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon RRM_1 PF00076.22 OWF43555.1 - 6.2e-19 67.6 0.0 1.3e-07 31.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF43555.1 - 0.14 11.7 0.0 7.2 6.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.17 OWF43556.1 - 7.3e-46 156.6 0.0 1.9e-45 155.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OWF43556.1 - 3e-42 144.8 0.0 7.6e-42 143.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OWF43556.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF43556.1 - 0.0038 16.0 0.1 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Patched PF02460.18 OWF43557.1 - 6.3e-95 318.9 20.9 8e-95 318.6 20.9 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF43557.1 - 4.2e-36 124.1 2.0 4.2e-36 124.1 2.0 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OWF43557.1 - 1.4 6.5 12.0 2 6.0 12.0 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TGF_beta PF00019.20 OWF43558.1 - 3.6e-19 69.6 0.1 8.1e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain MutS_V PF00488.21 OWF43559.1 - 4.9e-67 225.6 0.5 1.8e-66 223.8 0.1 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OWF43559.1 - 6.4e-30 104.8 0.9 1.3e-29 103.8 0.3 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OWF43559.1 - 6.7e-15 55.2 0.1 1.4e-12 47.7 0.0 3.2 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.17 OWF43559.1 - 1.3e-14 54.6 0.0 4.7e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 OWF43559.1 - 0.006 16.6 0.0 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OWF43559.1 - 0.081 12.8 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 OWF43559.1 - 0.11 12.3 0.1 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OWF43559.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1768 PF08719.11 OWF43560.1 - 1.2e-52 178.4 0.6 1.8e-52 177.8 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 OWF43560.1 - 0.016 15.0 0.2 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 FAM47 PF14642.6 OWF43561.1 - 4.8e-05 23.0 0.0 0.47 10.0 0.0 2.8 1 1 2 3 3 3 2 FAM47 family Imm3 PF14425.6 OWF43561.1 - 0.00033 20.7 0.3 0.093 12.8 0.0 2.6 1 1 2 3 3 3 1 Immunity protein Imm3 FPRL1_inhibitor PF16104.5 OWF43561.1 - 0.00064 19.8 0.0 5.4 7.2 0.0 3.9 1 1 3 4 4 4 1 Formyl peptide receptor-like 1 inhibitory protein DUF1192 PF06698.11 OWF43561.1 - 0.0016 18.5 0.0 57 3.9 0.0 5.2 2 2 1 5 5 5 0 Protein of unknown function (DUF1192) MRP-63 PF14978.6 OWF43561.1 - 0.0047 17.5 2.9 26 5.5 0.1 4.6 3 1 1 5 5 5 0 Mitochondrial ribosome protein 63 DUF2603 PF10788.9 OWF43561.1 - 0.0057 16.7 0.0 1.2 9.2 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2603) DUF4815 PF16075.5 OWF43561.1 - 0.01 14.1 3.7 1.1 7.5 0.2 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4815) MecA_N PF05223.11 OWF43561.1 - 0.028 14.7 0.0 3.9 7.8 0.0 3.0 1 1 2 3 3 3 0 NTF2-like N-terminal transpeptidase domain CclA_1 PF16942.5 OWF43561.1 - 0.039 14.2 6.8 6.5 7.1 0.3 3.4 1 1 2 3 3 3 0 Putative cyclic bacteriocin DUF1195 PF06708.11 OWF43561.1 - 0.044 13.6 8.1 1.2 8.9 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1195) Peptidase_M74 PF03411.13 OWF43561.1 - 0.097 12.2 0.3 9.5 5.7 0.0 3.0 1 1 2 4 4 4 0 Penicillin-insensitive murein endopeptidase MbeD_MobD PF04899.12 OWF43561.1 - 0.14 12.3 17.1 46 4.2 0.7 6.0 1 1 4 5 5 5 0 MbeD/MobD like OrfB_IS605 PF01385.19 OWF43561.1 - 0.25 11.6 9.6 12 6.2 0.1 3.6 3 1 1 4 4 4 0 Probable transposase FPRL1_inhibitor PF16104.5 OWF43562.1 - 1.4e-05 25.2 0.1 5.1 7.3 0.0 4.7 1 1 5 6 6 6 2 Formyl peptide receptor-like 1 inhibitory protein Imm3 PF14425.6 OWF43562.1 - 3.9e-05 23.7 0.1 0.35 10.9 0.0 2.9 1 1 2 3 3 3 2 Immunity protein Imm3 DUF1192 PF06698.11 OWF43562.1 - 0.00048 20.1 0.0 84 3.3 0.0 5.7 3 2 3 7 7 7 0 Protein of unknown function (DUF1192) FAM47 PF14642.6 OWF43562.1 - 0.0098 15.5 0.0 3 7.3 0.0 2.1 1 1 1 2 2 2 2 FAM47 family CclA_1 PF16942.5 OWF43562.1 - 0.011 16.0 6.2 2.7 8.3 0.3 3.2 1 1 2 3 3 3 0 Putative cyclic bacteriocin MecA_N PF05223.11 OWF43562.1 - 0.023 15.0 0.0 12 6.2 0.0 2.9 1 1 2 3 3 3 0 NTF2-like N-terminal transpeptidase domain DUF1195 PF06708.11 OWF43562.1 - 0.038 13.8 6.7 3.4 7.4 0.4 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1195) MRP-63 PF14978.6 OWF43562.1 - 0.055 14.1 0.5 29 5.4 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ribosome protein 63 TrpP PF17099.5 OWF43562.1 - 0.064 13.0 5.8 8.9 6.1 0.6 3.7 1 1 3 4 4 4 0 Tryptophan transporter TrpP Ins134_P3_kin PF05770.11 OWF43562.1 - 0.11 12.0 0.4 8.3 5.9 0.0 3.1 1 1 2 4 4 4 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Lant_dehydr_N PF04738.13 OWF43562.1 - 0.12 10.5 0.4 15 3.5 0.1 2.7 1 1 1 3 3 3 0 Lantibiotic dehydratase, N terminus Rac1 PF09632.10 OWF43562.1 - 8.7 5.4 10.5 13 4.8 1.1 2.8 1 1 4 5 5 5 0 Rac1-binding domain DUF1174 PF06671.11 OWF43563.1 - 7.9e-08 31.9 10.5 30 4.4 0.0 11.2 12 1 1 13 13 13 0 Repeat of unknown function (DUF1174) DUF1462 PF07315.11 OWF43563.1 - 9.4e-08 32.2 2.3 30 5.0 0.0 7.2 1 1 6 7 7 7 0 Protein of unknown function (DUF1462) DUF3239 PF11580.8 OWF43563.1 - 0.0027 18.0 0.0 3.5 8.0 0.0 3.6 1 1 2 4 4 4 1 Protein of unknown function (DUF3239) Fig1 PF12351.8 OWF43563.1 - 0.012 15.5 8.1 11 5.9 0.3 4.8 1 1 3 4 4 4 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4412 PF14371.6 OWF43563.1 - 0.055 13.3 4.1 28 4.5 0.1 4.1 1 1 5 6 6 6 0 Domain of unknown function (DUF4412) Amidase_6 PF12671.7 OWF43563.1 - 0.091 12.9 0.7 51 3.9 0.2 4.0 1 1 3 4 4 4 0 Putative amidase domain DUF2616 PF11077.8 OWF43563.1 - 0.095 12.4 0.7 1e+02 2.6 0.0 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF2616) Plk4_PB2 PF18409.1 OWF43563.1 - 0.13 13.0 11.6 1e+02 3.7 0.8 7.8 1 1 6 7 7 7 0 Polo-like Kinase 4 Polo Box 2 Phage_tail_T PF06223.12 OWF43563.1 - 0.33 11.5 11.5 54 4.4 0.1 5.4 1 1 5 6 6 6 0 Minor tail protein T Trehalose_PPase PF02358.16 OWF43563.1 - 1.9 7.6 5.3 58 2.7 0.2 4.0 1 1 4 5 5 5 0 Trehalose-phosphatase BNIP2 PF12496.8 OWF43563.1 - 2.3 8.7 4.6 5.5 7.4 2.7 2.4 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 B-block_TFIIIC PF04182.12 OWF43564.1 - 3.5e-14 52.7 0.3 4.7e-13 49.1 0.1 3.0 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC CARD PF00619.21 OWF43565.1 - 5.4e-17 61.6 0.2 6.8e-17 61.3 0.2 1.1 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF43565.1 - 6.1e-08 32.6 0.2 8.1e-08 32.2 0.2 1.1 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.22 OWF43565.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Death domain Mito_carr PF00153.27 OWF43566.1 - 7.1e-52 173.3 3.7 6.9e-21 74.0 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF43566.1 - 0.0017 17.6 1.2 0.088 11.9 0.0 2.9 2 1 1 3 3 3 2 Gammaproteobacterial serine protease Cyto_heme_lyase PF01265.17 OWF43568.1 - 2.1 7.8 9.3 3.7 7.1 9.0 1.5 1 1 0 1 1 1 0 Cytochrome c/c1 heme lyase Death PF00531.22 OWF43569.1 - 0.02 15.0 0.1 0.043 14.0 0.1 1.7 1 1 0 1 1 1 0 Death domain CBFD_NFYB_HMF PF00808.23 OWF43570.1 - 8.4e-29 99.7 0.8 1.2e-28 99.2 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OWF43570.1 - 1.7e-06 28.4 0.0 2.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 OWF43570.1 - 0.0014 18.6 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 OWF43570.1 - 0.0028 17.7 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-X PF09415.10 OWF43570.1 - 0.077 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PAN_3 PF08277.12 OWF43570.1 - 0.083 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain Bromo_TP PF07524.13 OWF43570.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 OWF43570.1 - 0.19 12.3 1.6 0.22 12.0 0.0 1.9 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A ubiquitin PF00240.23 OWF43571.1 - 2.1e-19 69.0 0.1 3.3e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Tugs PF17840.1 OWF43571.1 - 3.2e-12 46.4 0.4 5.4e-12 45.7 0.4 1.3 1 0 0 1 1 1 1 Tethering Ubl4a to BAGS domain Rad60-SLD PF11976.8 OWF43571.1 - 1.3e-08 34.5 0.3 2.8e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OWF43571.1 - 0.00026 21.0 0.3 0.14 12.2 0.1 2.4 1 1 1 2 2 2 2 Ubiquitin-like domain Ubiquitin_2 PF14560.6 OWF43571.1 - 0.002 18.6 0.0 0.005 17.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain ThiS-like PF14453.6 OWF43571.1 - 0.015 15.3 0.1 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 ThiS-like ubiquitin 3-HAO PF06052.12 OWF43571.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase MCD PF05292.11 OWF43572.1 - 0.0071 15.9 0.0 33 3.9 0.0 4.3 1 1 2 6 6 6 3 Malonyl-CoA decarboxylase C-terminal domain Kelch_6 PF13964.6 OWF43573.1 - 2e-31 107.2 8.6 1.5e-06 28.3 0.1 6.2 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 OWF43573.1 - 8.6e-27 92.6 10.2 6.2e-05 22.9 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 OWF43573.1 - 5e-26 90.0 11.1 1e-05 25.0 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OWF43573.1 - 6e-20 71.1 4.6 0.00048 20.3 0.0 7.0 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF43573.1 - 3.9e-18 65.2 12.6 8.9e-06 25.6 0.0 6.4 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF43573.1 - 6.5e-16 57.6 16.2 6.4e-05 22.8 0.3 6.8 6 2 0 6 6 6 4 Kelch motif RAG2 PF03089.14 OWF43573.1 - 0.002 17.2 0.0 3 6.7 0.0 3.1 2 1 1 3 3 3 2 Recombination activating protein 2 zf-C3HC PF07967.13 OWF43574.1 - 1.1e-30 106.3 2.4 1.8e-27 96.0 0.3 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 OWF43574.1 - 1.6e-14 53.8 2.8 2.7e-13 49.9 0.2 3.0 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.21 OWF43574.1 - 0.17 12.5 4.8 3.8 8.2 0.4 3.0 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain UQ_con PF00179.26 OWF43575.1 - 2.5e-36 124.4 0.0 3.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SDP_N PF12278.8 OWF43575.1 - 0.73 10.0 4.2 1.2 9.3 4.2 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal TatD_DNase PF01026.21 OWF43576.1 - 3.7e-57 193.6 0.0 5.2e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase CARD PF00619.21 OWF43577.1 - 2.8e-07 30.5 1.2 1.2e-06 28.5 0.1 2.6 2 0 0 2 2 2 1 Caspase recruitment domain ATG16 PF08614.11 OWF43577.1 - 0.0034 17.6 27.7 0.0034 17.6 27.7 2.4 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.12 OWF43577.1 - 0.03 14.4 4.1 0.068 13.3 0.5 2.9 1 1 1 2 2 2 0 MbeD/MobD like FlaC_arch PF05377.11 OWF43577.1 - 0.6 10.5 11.0 3.7 8.0 0.4 4.1 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 OWF43577.1 - 0.69 9.8 8.9 8.8 6.3 0.2 3.9 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 OWF43577.1 - 0.81 9.8 20.6 2.7 8.2 2.3 4.6 3 1 1 4 4 4 0 bZIP transcription factor COX4 PF02936.14 OWF43577.1 - 0.99 9.4 5.2 0.4 10.7 0.9 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Metal_resist PF13801.6 OWF43577.1 - 1.4 9.2 9.4 3.3 7.9 0.2 3.0 2 1 0 3 3 3 0 Heavy-metal resistance Bap31_Bap29_C PF18035.1 OWF43577.1 - 1.4 9.0 13.1 2.4 8.2 3.9 3.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 OWF43577.1 - 2.7 8.3 20.2 2.2 8.5 3.0 4.8 4 1 0 4 4 4 0 Homeobox associated leucine zipper GAS PF13851.6 OWF43577.1 - 2.8 7.2 39.1 0.089 12.1 13.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3209 PF11483.8 OWF43577.1 - 4 7.9 14.2 3.6 8.1 2.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3209) DUF724 PF05266.14 OWF43577.1 - 7.5 6.3 22.4 0.14 11.9 13.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Med21 PF11221.8 OWF43577.1 - 8.9 6.6 24.6 0.45 10.7 15.0 3.9 2 2 0 2 2 2 0 Subunit 21 of Mediator complex TPR_MLP1_2 PF07926.12 OWF43577.1 - 9 6.4 36.8 0.45 10.6 8.1 4.5 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein zf-C3HC4 PF00097.25 OWF43578.1 - 0.0089 15.9 4.5 0.0089 15.9 4.5 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF43578.1 - 0.012 15.6 16.6 0.017 15.1 9.4 2.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF43578.1 - 2.7 8.1 18.5 6.7 6.8 10.6 3.0 2 0 0 2 2 2 0 RING-type zinc-finger STIMATE PF12400.8 OWF43579.1 - 6.4e-36 123.7 8.6 6.4e-36 123.7 8.6 1.7 2 0 0 2 2 2 1 STIMATE family Blt1_C PF17183.4 OWF43579.1 - 0.025 14.2 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain Phage_Gp23 PF10669.9 OWF43579.1 - 0.24 11.7 1.8 0.57 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF846 PF05832.12 OWF43579.1 - 6.2 6.9 11.3 2.6 8.1 5.1 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) MBT PF02820.18 OWF43580.1 - 1.7e-87 287.7 5.6 6.5e-23 80.9 0.1 4.5 4 0 0 4 4 4 4 mbt repeat SLED PF12140.8 OWF43580.1 - 8.7e-36 122.8 2.1 2.3e-35 121.5 2.1 1.8 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 OWF43580.1 - 7.3e-09 36.0 0.1 1.3e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF43580.1 - 1.3e-06 28.4 0.1 2.6e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 OWF43580.1 - 0.0033 17.6 0.1 0.0075 16.5 0.1 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 OWF43580.1 - 0.0077 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain RAC_head PF16717.5 OWF43581.1 - 1e-19 71.3 10.5 1e-19 71.3 10.5 4.2 3 2 2 5 5 5 1 Ribosome-associated complex head domain DnaJ PF00226.31 OWF43581.1 - 4.8e-16 58.6 2.3 6.8e-16 58.2 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 OWF43581.1 - 4.4e-15 55.6 0.9 4.3e-08 33.2 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF43581.1 - 7.7e-08 32.5 9.8 1.4e-05 25.3 0.1 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain ADP_ribosyl_GH PF03747.14 OWF43582.1 - 3.3e-52 178.0 0.0 3.8e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase NHL PF01436.21 OWF43583.1 - 0.002 18.1 7.4 0.089 12.9 0.3 4.4 4 1 0 4 4 4 2 NHL repeat Reg_prop PF07494.11 OWF43583.1 - 0.064 13.5 0.1 13 6.4 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller zf-Tim10_DDP PF02953.15 OWF43583.1 - 0.14 11.8 1.6 0.95 9.2 0.3 2.4 2 0 0 2 2 2 0 Tim10/DDP family zinc finger DUF1690 PF07956.11 OWF43584.1 - 3.2e-07 30.9 10.4 5e-07 30.2 10.4 1.4 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) V-ATPase_G PF03179.15 OWF43584.1 - 0.0045 17.5 6.4 0.0083 16.6 6.4 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit C_GCAxxG_C_C PF09719.10 OWF43584.1 - 0.0075 16.5 2.7 0.011 16.0 2.7 1.4 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) CHCH PF06747.13 OWF43584.1 - 0.031 14.4 2.8 0.031 14.4 2.8 2.0 2 0 0 2 2 2 0 CHCH domain ATP-synt_B PF00430.18 OWF43584.1 - 0.24 11.5 7.9 0.44 10.6 7.9 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF883 PF05957.13 OWF43584.1 - 1.5 9.5 4.3 1.6 9.4 3.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Y_phosphatase PF00102.27 OWF43585.1 - 2.9e-128 426.3 0.2 1.4e-78 263.7 0.1 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 OWF43585.1 - 1.2e-53 179.4 7.5 2.6e-16 59.8 0.1 4.9 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF43585.1 - 2.9e-08 34.2 7.5 0.00063 20.3 0.0 4.9 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 OWF43585.1 - 1.7e-05 25.3 1.6 0.00029 21.4 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 OWF43585.1 - 0.00069 19.7 0.5 0.0032 17.6 0.1 2.5 2 0 0 2 2 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF43585.1 - 0.00085 19.6 0.3 0.006 16.9 0.3 2.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF43585.1 - 0.0023 18.0 0.2 0.078 13.1 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin I-set domain V-set PF07686.17 OWF43585.1 - 0.0042 17.2 1.1 0.054 13.7 0.2 2.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain Interfer-bind PF09294.10 OWF43585.1 - 0.015 15.6 0.1 5.6 7.3 0.0 3.7 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Y_phosphatase3 PF13350.6 OWF43585.1 - 0.023 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 OWF43585.1 - 0.024 14.4 0.0 0.078 12.8 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF43585.1 - 0.046 13.8 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF5414 PF17435.2 OWF43585.1 - 0.094 12.4 0.2 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5414) DUF2369 PF10179.9 OWF43585.1 - 0.24 11.8 0.9 31 5.0 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) Bax1-I PF01027.20 OWF43586.1 - 8.1e-48 163.0 32.7 9.6e-48 162.7 32.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 eIF-3c_N PF05470.12 OWF43586.1 - 0.2 9.9 0.1 0.27 9.5 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4079 PF13301.6 OWF43586.1 - 2.8 8.1 10.1 0.12 12.5 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) p450 PF00067.22 OWF43587.1 - 1.1e-86 291.5 0.0 1.2e-86 291.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CortBP2 PF09727.9 OWF43588.1 - 2.7e-76 255.7 22.8 2.7e-76 255.7 22.8 2.3 2 0 0 2 2 2 1 Cortactin-binding protein-2 Ank_2 PF12796.7 OWF43588.1 - 6.9e-38 129.1 0.6 1.5e-14 54.3 0.0 4.0 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF43588.1 - 6e-25 87.3 8.9 2e-11 44.1 0.2 5.4 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF43588.1 - 2.2e-20 72.1 8.2 3.4e-06 27.3 0.1 5.7 4 1 1 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF43588.1 - 3.1e-20 72.0 1.0 2.5e-10 40.4 0.2 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF43588.1 - 1e-15 56.2 0.7 0.0011 19.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat AAA_5 PF07728.14 OWF43588.1 - 2.1e-06 27.8 0.0 5.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OWF43588.1 - 0.038 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OWF43588.1 - 0.038 13.5 0.1 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OWF43588.1 - 0.05 13.9 0.2 0.92 9.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain NPV_P10 PF05531.12 OWF43588.1 - 0.056 13.9 2.8 1.9 9.0 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA PF00004.29 OWF43588.1 - 0.06 13.8 0.1 0.23 11.9 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OWF43588.1 - 0.063 13.7 0.3 0.55 10.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF3138 PF11336.8 OWF43588.1 - 0.14 10.7 0.9 0.26 9.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3037 PF11236.8 OWF43588.1 - 0.27 11.7 8.1 0.1 13.0 3.4 2.8 4 1 1 5 5 3 0 Protein of unknown function (DUF3037) PNPase_C PF12111.8 OWF43588.1 - 0.28 10.6 2.4 0.69 9.4 2.4 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Maelstrom PF13017.6 OWF43589.1 - 0.031 13.9 0.2 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Homeodomain PF00046.29 OWF43592.1 - 6.6e-20 70.7 1.7 1.4e-19 69.7 1.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF43592.1 - 0.074 13.0 0.4 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.8 OWF43592.1 - 0.079 12.4 1.4 0.091 12.2 0.2 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez FAM176 PF14851.6 OWF43592.1 - 0.18 11.5 2.8 0.34 10.6 2.8 1.5 1 0 0 1 1 1 0 FAM176 family Nepo_coat PF03391.15 OWF43593.1 - 0.059 12.8 0.2 0.086 12.3 0.2 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, central domain SepF PF04472.12 OWF43594.1 - 0.021 15.1 0.1 0.54 10.6 0.1 2.4 2 0 0 2 2 2 0 Cell division protein SepF DUF4297 PF14130.6 OWF43594.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4297) Smoothelin PF12510.8 OWF43594.1 - 0.49 10.5 1.6 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Glyco_hydro_31 PF01055.26 OWF43597.1 - 4.7e-142 474.3 6.2 7e-142 473.7 6.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OWF43597.1 - 1.1e-23 83.6 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OWF43597.1 - 6.1e-07 29.7 0.2 2e-06 28.0 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Trefoil PF00088.18 OWF43597.1 - 0.0046 16.8 1.3 0.0087 15.9 1.3 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain BsuBI_PstI_RE_N PF17728.1 OWF43598.1 - 0.55 10.1 3.5 13 5.7 0.1 3.1 1 1 2 3 3 3 0 BsuBI/PstI restriction endonuclease HTH domain Peptidase_M10 PF00413.24 OWF43599.1 - 1.8e-55 187.1 0.8 3.2e-55 186.3 0.8 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 OWF43599.1 - 1.4e-49 165.8 17.8 2.3e-15 56.2 1.0 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 OWF43599.1 - 1.1e-08 35.1 0.0 3.1e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 OWF43599.1 - 7.3e-05 22.5 1.3 0.035 13.7 0.1 2.6 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 OWF43599.1 - 0.0026 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 OWF43599.1 - 0.0092 15.6 0.6 0.017 14.7 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF43599.1 - 0.036 14.6 0.4 0.097 13.2 0.4 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 OWF43599.1 - 0.059 12.6 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 OWF43599.1 - 0.16 12.1 2.8 0.13 12.4 0.6 1.8 2 1 0 2 2 2 0 Metallo-peptidase family M12 nos_propeller PF18764.1 OWF43600.1 - 1.1e-05 25.3 8.6 25 4.9 0.0 8.2 1 1 8 10 10 10 1 Nitrous oxide reductase propeller repeat TM2 PF05154.16 OWF43600.1 - 0.00021 21.5 6.1 1.8e+02 2.6 0.0 8.5 8 1 1 9 9 9 0 TM2 domain Leptin PF02024.15 OWF43600.1 - 0.00039 20.2 0.0 15 5.3 0.0 4.7 1 1 4 5 5 5 1 Leptin DUF3235 PF11574.8 OWF43600.1 - 0.0021 18.9 4.6 34 5.4 0.0 5.8 1 1 6 7 7 7 0 Protein of unknown function (DUF3235) HNH_4 PF13395.6 OWF43600.1 - 0.0082 16.0 5.4 34 4.4 0.0 6.4 4 3 1 6 6 6 0 HNH endonuclease Dam PF05869.11 OWF43600.1 - 0.01 15.4 5.5 7.5 6.1 0.1 4.1 1 1 3 4 4 4 3 DNA N-6-adenine-methyltransferase (Dam) PL48 PF15903.5 OWF43600.1 - 0.095 11.7 0.0 20 4.0 0.0 2.9 1 1 2 3 3 3 0 Filopodia upregulated, FAM65 Ribosomal_S6 PF01250.17 OWF43601.1 - 0.00058 20.1 18.2 0.6 10.4 4.1 4.1 1 1 2 3 3 3 3 Ribosomal protein S6 Phage_int_SAM_4 PF13495.6 OWF43601.1 - 0.00082 19.8 15.4 0.78 10.3 1.2 4.1 1 1 3 4 4 4 3 Phage integrase, N-terminal SAM-like domain DUF2810 PF10928.8 OWF43601.1 - 0.002 18.1 10.2 15 5.7 0.1 5.4 2 1 2 6 6 6 0 Protein of unknown function (DUF2810) RE_MjaI PF09568.10 OWF43601.1 - 0.0025 17.7 30.9 0.71 9.7 2.4 4.2 1 1 3 4 4 4 4 MjaI restriction endonuclease HMD PF03201.16 OWF43601.1 - 0.031 14.5 11.7 2.6 8.3 0.7 3.4 1 1 2 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DNA_ligase_C PF17879.1 OWF43601.1 - 0.039 14.0 9.7 15 5.7 0.1 4.2 1 1 2 3 3 3 0 DNA ligase C-terminal domain DUF3069 PF11269.8 OWF43601.1 - 0.054 13.8 14.9 2 8.7 1.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3069) Anti-adapt_IraP PF10796.9 OWF43601.1 - 0.17 12.5 11.0 12 6.6 0.8 3.6 1 1 3 4 4 4 0 Sigma-S stabilisation anti-adaptor protein DUF1930 PF09122.10 OWF43601.1 - 0.18 11.8 4.8 38 4.3 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1930) DUF5388 PF17363.2 OWF43601.1 - 0.23 11.7 6.5 7.9 6.8 0.5 3.1 1 1 1 3 3 3 0 Family of unknown function (DUF5388) P-mevalo_kinase PF04275.14 OWF43601.1 - 0.29 11.1 18.4 3.6 7.6 1.6 3.9 1 1 3 4 4 4 0 Phosphomevalonate kinase IZUMO PF15005.6 OWF43601.1 - 0.4 11.2 18.5 4.1 7.9 8.2 2.5 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated TetR_C_25 PF17933.1 OWF43601.1 - 0.49 10.7 3.0 1.9 8.8 0.7 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF445 PF04286.12 OWF43601.1 - 0.61 9.8 16.6 1.6 8.5 16.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Catalase-rel PF06628.12 OWF43601.1 - 0.62 10.3 6.3 64 3.9 0.2 4.4 1 1 2 3 3 3 0 Catalase-related immune-responsive Peptidase_C39_2 PF13529.6 OWF43601.1 - 0.9 10.1 13.9 1.7 9.2 5.0 2.5 1 1 1 2 2 2 0 Peptidase_C39 like family SpoVIF PF14069.6 OWF43601.1 - 0.9 9.4 15.8 7.4 6.4 0.4 3.5 3 1 0 3 3 3 0 Stage VI sporulation protein F CART PF06373.11 OWF43601.1 - 2.6 8.3 10.7 65 3.8 0.3 3.9 1 1 4 5 5 5 0 Cocaine and amphetamine regulated transcript protein (CART) Serpin PF00079.20 OWF43601.1 - 3 7.1 19.4 4.3 6.5 2.0 3.1 1 1 2 3 3 3 0 Serpin (serine protease inhibitor) PriX PF18689.1 OWF43601.1 - 3.6 8.0 15.0 8.2 6.8 4.4 2.9 1 1 2 3 3 3 0 Primase X Suv3_N PF18114.1 OWF43601.1 - 5.2 7.2 5.5 54 3.9 0.3 2.8 1 1 1 2 2 2 0 Suv3 helical N-terminal domain Tfb2 PF03849.14 OWF43601.1 - 5.6 5.8 17.8 2.2 7.2 3.7 2.8 1 1 0 2 2 2 0 Transcription factor Tfb2 Mpt_N PF09176.11 OWF43601.1 - 8.5 6.6 6.0 1.1e+02 3.1 0.1 3.6 3 1 1 4 4 4 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal HTH_34 PF13601.6 OWF43601.1 - 9.3 6.5 15.8 19 5.6 1.0 3.8 1 1 2 3 3 3 0 Winged helix DNA-binding domain SelR PF01641.18 OWF43602.1 - 4e-51 172.2 0.6 5.2e-51 171.8 0.6 1.1 1 0 0 1 1 1 1 SelR domain GFA PF04828.14 OWF43602.1 - 0.017 15.4 1.8 1.3 9.4 0.2 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 OWF43602.1 - 0.018 15.2 0.2 0.031 14.5 0.2 1.4 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.6 OWF43602.1 - 0.066 12.7 4.2 3.5 7.2 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 OWF43602.1 - 0.42 10.7 3.6 3.3 7.8 3.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.24 OWF43604.1 - 1.2e-06 28.5 19.6 4.7e-06 26.7 6.4 5.4 4 1 1 5 5 4 2 B-box zinc finger zf-RING_5 PF14634.6 OWF43604.1 - 0.00031 20.6 15.2 0.00031 20.6 15.2 4.2 4 1 0 4 4 3 1 zinc-RING finger domain Invasin_D3 PF09134.10 OWF43604.1 - 0.0019 18.5 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 Invasin, domain 3 Filamin PF00630.19 OWF43604.1 - 0.0068 17.2 2.4 0.0071 17.2 0.1 2.3 2 1 0 2 2 2 1 Filamin/ABP280 repeat zf-C3HC4 PF00097.25 OWF43604.1 - 0.0088 15.9 15.0 0.0088 15.9 15.0 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) hDGE_amylase PF14701.6 OWF43604.1 - 0.076 12.1 3.6 0.11 11.5 3.6 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CENP-Q PF13094.6 OWF43604.1 - 0.11 12.7 7.2 0.19 11.9 7.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PIN_8 PF18476.1 OWF43604.1 - 0.13 12.1 5.3 0.28 11.0 5.3 1.6 1 0 0 1 1 1 0 PIN like domain DUF4965 PF16335.5 OWF43604.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) DUF724 PF05266.14 OWF43604.1 - 0.18 11.6 12.7 0.32 10.8 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 OWF43604.1 - 0.2 11.2 4.6 0.33 10.5 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TRAF6_Z2 PF18048.1 OWF43604.1 - 0.75 9.9 7.2 1.7 8.8 0.1 3.7 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Spc7 PF08317.11 OWF43604.1 - 0.85 8.4 12.9 1.5 7.6 12.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-UDP PF14569.6 OWF43604.1 - 0.93 9.7 18.3 12 6.1 0.1 4.9 4 1 1 5 5 5 0 Zinc-binding RING-finger Pinin_SDK_memA PF04696.13 OWF43604.1 - 1.2 9.1 12.2 2.8 8.0 12.2 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF1043 PF06295.12 OWF43604.1 - 5.4 7.0 7.8 13 5.8 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Rubi_NSP_C PF12601.8 OWF43605.1 - 0.00046 20.2 6.9 15 5.7 0.0 5.5 5 1 1 6 6 6 3 Rubivirus non-structural protein SabA_adhesion PF18304.1 OWF43605.1 - 0.067 12.4 3.3 13 5.0 0.1 3.7 2 2 0 2 2 2 0 SabA N-terminal extracellular adhesion domain DUF5465 PF17553.2 OWF43605.1 - 2.4 8.9 16.9 66 4.5 0.1 5.6 6 0 0 6 6 6 0 Family of unknown function (DUF5465) CEND1 PF15677.5 OWF43605.1 - 2.7 8.5 6.7 10 6.7 0.0 3.7 2 2 2 4 4 4 0 Cell cycle exit and neuronal differentiation protein 1 UPF0547 PF10571.9 OWF43605.1 - 8.1 6.6 8.1 1.3e+02 2.8 0.0 4.3 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 Fibrinogen_C PF00147.18 OWF43606.1 - 2.9e-25 89.4 0.9 3.2e-25 89.3 0.9 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Hexapep PF00132.24 OWF43607.1 - 9.6e-11 41.0 17.6 4.2e-05 23.1 2.4 4.3 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OWF43607.1 - 0.00017 21.3 8.3 0.0069 16.1 0.7 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OWF43607.1 - 0.013 14.5 3.6 0.18 10.7 0.2 2.1 1 1 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 OWF43607.1 - 0.043 11.9 0.9 0.054 11.6 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Sec23_trunk PF04811.15 OWF43608.1 - 1.3e-76 257.4 0.1 3e-76 256.2 0.1 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OWF43608.1 - 1.7e-21 76.0 0.6 2.9e-21 75.2 0.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OWF43608.1 - 3.3e-21 75.8 0.0 6.2e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OWF43608.1 - 1.1e-14 54.1 5.0 2.5e-14 53.1 5.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OWF43608.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Myosin_head PF00063.21 OWF43610.1 - 1.3e-285 949.0 0.4 1.3e-285 949.0 0.4 3.2 4 0 0 4 4 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 OWF43610.1 - 1.8e-177 592.4 263.6 2.3e-177 592.0 263.6 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 OWF43610.1 - 3e-16 59.0 0.7 7e-16 57.8 0.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 OWF43610.1 - 1.8e-06 28.0 149.9 0.069 13.2 5.8 14.2 1 1 15 16 16 16 11 Protein of unknown function (DUF1664) ATG16 PF08614.11 OWF43610.1 - 2e-05 24.9 255.5 0.068 13.4 22.6 11.1 2 1 10 12 12 11 6 Autophagy protein 16 (ATG16) Filament PF00038.21 OWF43610.1 - 6.9e-05 22.6 41.6 6.9e-05 22.6 41.6 8.2 1 1 6 7 7 7 3 Intermediate filament protein Lebercilin PF15619.6 OWF43610.1 - 0.00033 20.4 46.7 0.00033 20.4 46.7 10.1 2 2 4 9 9 7 2 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 OWF43610.1 - 0.00038 20.6 2.8 0.00038 20.6 2.8 11.1 1 1 8 12 12 11 4 Fibrinogen alpha/beta chain family IQ PF00612.27 OWF43610.1 - 0.00072 19.1 6.1 0.003 17.2 0.6 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif TPR_MLP1_2 PF07926.12 OWF43610.1 - 0.00094 19.3 5.7 0.00094 19.3 5.7 12.1 2 2 10 12 12 10 4 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OWF43610.1 - 0.0024 16.8 33.5 0.0024 16.8 33.5 10.6 1 1 10 12 12 12 4 Spc7 kinetochore protein ERM PF00769.19 OWF43610.1 - 0.0044 16.9 26.5 0.0044 16.9 26.5 9.4 1 1 7 8 8 7 2 Ezrin/radixin/moesin family Leu_zip PF15294.6 OWF43610.1 - 0.0044 16.6 21.2 0.0044 16.6 21.2 9.7 1 1 8 9 9 9 1 Leucine zipper Cnn_1N PF07989.11 OWF43610.1 - 0.0073 16.4 4.4 0.0073 16.4 4.4 16.5 5 4 6 12 12 9 1 Centrosomin N-terminal motif 1 LPP PF04728.13 OWF43610.1 - 0.011 16.2 0.1 0.011 16.2 0.1 14.3 8 5 4 12 12 10 0 Lipoprotein leucine-zipper AAA_22 PF13401.6 OWF43610.1 - 0.29 11.4 0.0 0.29 11.4 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 OWF43610.1 - 0.46 10.9 0.0 0.46 10.9 0.0 6.8 5 3 0 5 5 2 0 AAA ATPase domain DUF812 PF05667.11 OWF43610.1 - 3.4 6.5 225.8 0.13 11.1 31.8 7.9 1 1 6 7 7 6 0 Protein of unknown function (DUF812) Img2 PF05046.14 OWF43610.1 - 6.6 7.1 15.5 19 5.6 0.1 5.9 4 2 0 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) Myosin_head PF00063.21 OWF43611.1 - 1.4e-286 952.2 0.3 1.4e-286 952.2 0.3 2.7 3 0 0 3 3 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 OWF43611.1 - 3.8e-121 405.8 206.8 2.5e-61 207.8 88.5 2.1 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 OWF43611.1 - 9.3e-14 51.0 0.3 2.2e-13 49.8 0.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Lebercilin PF15619.6 OWF43611.1 - 0.00011 22.0 46.7 0.00011 22.0 46.7 8.6 3 2 5 8 8 6 1 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 OWF43611.1 - 0.00012 22.3 25.3 0.00028 21.1 2.5 9.0 2 2 6 10 10 9 3 Fibrinogen alpha/beta chain family IQ PF00612.27 OWF43611.1 - 0.00058 19.4 6.1 0.0026 17.4 0.6 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif TPR_MLP1_2 PF07926.12 OWF43611.1 - 0.001 19.2 7.7 0.001 19.2 7.7 9.9 3 2 3 8 8 8 4 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OWF43611.1 - 0.003 16.5 31.9 0.003 16.5 31.9 8.1 1 1 9 10 10 10 4 Spc7 kinetochore protein LPP PF04728.13 OWF43611.1 - 0.0089 16.4 0.1 0.0089 16.4 0.1 10.2 7 2 3 10 10 10 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 OWF43611.1 - 0.0098 15.9 116.3 0.054 13.5 8.7 11.4 3 2 10 14 14 13 7 Protein of unknown function (DUF1664) Fez1 PF06818.15 OWF43611.1 - 0.01 16.3 32.2 0.01 16.3 32.2 7.0 2 2 5 7 7 6 0 Fez1 DUF812 PF05667.11 OWF43611.1 - 0.21 10.5 167.8 0.069 12.0 32.8 5.1 1 1 3 4 4 4 0 Protein of unknown function (DUF812) Bacillus_HBL PF05791.11 OWF43611.1 - 0.27 11.0 84.0 0.098 12.5 3.2 9.2 6 3 2 9 9 9 0 Bacillus haemolytic enterotoxin (HBL) AAA_22 PF13401.6 OWF43611.1 - 0.45 10.8 0.0 0.45 10.8 0.0 4.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OWF43611.1 - 0.72 10.2 0.0 0.72 10.2 0.0 5.6 4 2 0 4 4 1 0 AAA ATPase domain Img2 PF05046.14 OWF43611.1 - 4.7 7.6 10.9 18 5.7 0.1 5.0 3 2 1 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) VCBS PF13517.6 OWF43613.1 - 2.5e-06 28.0 16.5 0.049 14.2 1.8 4.2 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.6 OWF43613.1 - 0.0005 19.7 0.0 0.012 15.2 0.0 2.5 2 1 1 3 3 3 1 PQQ-like domain FG-GAP PF01839.23 OWF43613.1 - 0.0012 18.9 24.8 0.065 13.4 1.2 4.9 5 0 0 5 5 5 3 FG-GAP repeat EF-hand_1 PF00036.32 OWF43613.1 - 0.11 12.1 5.4 1.2 8.9 0.0 3.5 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 OWF43613.1 - 0.48 10.5 2.3 14 5.9 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 OWF43613.1 - 0.49 10.0 12.4 0.64 9.6 0.1 3.8 4 0 0 4 4 4 0 EF hand HMG_box PF00505.19 OWF43614.1 - 2.8e-19 69.3 0.2 6.1e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF43614.1 - 1.9e-10 41.2 0.4 3.9e-10 40.2 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain TIG PF01833.24 OWF43615.1 - 1.1e-96 317.0 140.5 7e-16 58.1 6.9 13.3 12 1 0 12 12 12 11 IPT/TIG domain G8 PF10162.9 OWF43615.1 - 9e-57 190.5 1.5 1.1e-32 112.7 0.2 3.4 3 0 0 3 3 3 2 G8 domain RIFIN PF02009.16 OWF43615.1 - 2.5 7.9 8.4 6.4 6.6 8.4 1.6 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 OWF43615.1 - 4.4 6.6 7.5 11 5.3 7.5 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lectin_C PF00059.21 OWF43616.1 - 3.2e-12 47.1 0.0 4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain IgGFc_binding PF17517.2 OWF43617.1 - 2.2e-44 151.9 10.0 3e-44 151.5 10.0 1.2 1 0 0 1 1 1 1 IgGFc binding protein BTB_2 PF02214.22 OWF43618.1 - 6.9e-19 68.0 0.1 1.5e-18 66.9 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain Ig_3 PF13927.6 OWF43619.1 - 7.6e-16 58.5 8.6 1.1e-05 25.9 0.1 5.5 3 2 2 5 5 5 3 Immunoglobulin domain V-set PF07686.17 OWF43619.1 - 2.9e-15 56.4 0.1 0.00022 21.4 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF43619.1 - 1.8e-13 50.6 2.6 0.0034 17.7 0.0 6.4 6 1 0 6 6 6 3 Immunoglobulin domain I-set PF07679.16 OWF43619.1 - 2.1e-10 40.5 1.4 0.97 9.5 0.1 6.0 5 2 0 5 5 5 4 Immunoglobulin I-set domain ig PF00047.25 OWF43619.1 - 2e-07 31.1 4.2 0.1 12.8 0.2 5.4 4 2 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 OWF43619.1 - 1.3e-05 25.1 0.9 0.045 13.8 0.1 3.3 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 OWF43619.1 - 0.00068 19.4 0.5 0.33 10.7 0.0 3.4 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Izumo-Ig PF16706.5 OWF43619.1 - 0.014 15.4 0.5 47 4.1 0.0 4.4 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Ndc1_Nup PF09531.10 OWF43621.1 - 1.2 7.7 5.4 1.6 7.4 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TrkA_TMD PF18613.1 OWF43621.1 - 4.7 6.7 5.8 7.8 6.0 5.8 1.3 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain Hid1 PF12722.7 OWF43622.1 - 2 6.5 9.3 2.7 6.0 9.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 OWF43622.1 - 6.7 5.3 9.8 9.1 4.8 9.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F5_F8_type_C PF00754.25 OWF43623.1 - 7.1e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain CBM_14 PF01607.24 OWF43623.1 - 5.8e-06 26.4 10.4 5.8e-06 26.4 10.4 5.0 5 0 0 5 5 5 1 Chitin binding Peritrophin-A domain F5_F8_type_C PF00754.25 OWF43624.1 - 1.6e-19 70.3 0.1 1.6e-19 70.3 0.1 1.9 2 0 0 2 2 2 1 F5/8 type C domain CBM_14 PF01607.24 OWF43624.1 - 1.9e-09 37.5 5.0 3.9e-09 36.5 5.0 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain TFIIA PF03153.13 OWF43624.1 - 0.0012 18.9 11.4 0.0013 18.8 11.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 OWF43624.1 - 0.0066 16.4 5.9 0.0097 15.9 5.9 1.2 1 0 0 1 1 1 1 Velvet factor Suf PF05843.14 OWF43624.1 - 0.015 15.3 4.1 0.018 15.0 4.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SOG2 PF10428.9 OWF43624.1 - 0.034 13.4 12.5 0.045 13.0 12.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2981 PF11200.8 OWF43624.1 - 0.049 13.4 4.2 0.068 12.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) MTP18 PF10558.9 OWF43624.1 - 0.052 13.5 2.5 0.094 12.7 2.5 1.3 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Endostatin PF06482.11 OWF43624.1 - 0.12 11.8 6.6 0.17 11.3 6.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 OWF43624.1 - 0.15 11.1 3.6 0.2 10.6 3.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 OWF43624.1 - 0.16 9.1 8.0 0.19 8.8 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SANTA PF09133.10 OWF43624.1 - 0.17 12.4 0.8 0.58 10.7 0.0 2.2 2 0 0 2 2 2 0 SANTA (SANT Associated) DUF4820 PF16091.5 OWF43624.1 - 0.22 10.8 6.6 0.33 10.3 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) UDPGT PF00201.18 OWF43624.1 - 0.32 9.7 1.7 0.44 9.3 1.7 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase RIFIN PF02009.16 OWF43624.1 - 1.3 8.9 10.2 1.8 8.4 10.2 1.2 1 0 0 1 1 1 0 Rifin Tim54 PF11711.8 OWF43624.1 - 1.8 7.3 6.8 2.6 6.7 6.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 OWF43624.1 - 2 8.6 9.2 3 8.0 9.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TP53IP5 PF15331.6 OWF43624.1 - 5.1 7.2 9.4 8.3 6.5 9.4 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF3408 PF11888.8 OWF43624.1 - 6.9 6.8 9.1 12 6.1 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CBM_14 PF01607.24 OWF43625.1 - 6.1e-07 29.5 6.7 6.1e-07 29.5 6.7 2.4 2 1 0 2 2 2 1 Chitin binding Peritrophin-A domain Antistasin PF02822.14 OWF43625.1 - 0.0065 17.1 5.3 0.15 12.7 0.3 3.2 2 1 0 2 2 2 2 Antistasin family CUE PF02845.16 OWF43626.1 - 4.9e-08 32.5 0.2 9.2e-08 31.6 0.2 1.5 1 0 0 1 1 1 1 CUE domain Selenoprotein_S PF06936.11 OWF43627.1 - 2e-32 112.6 1.7 2.4e-32 112.3 1.7 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) YqfQ PF14181.6 OWF43627.1 - 0.012 15.8 0.5 0.015 15.5 0.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF4407 PF14362.6 OWF43627.1 - 0.017 14.5 1.7 0.021 14.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CRA PF06589.11 OWF43627.1 - 0.029 14.5 0.6 0.041 14.0 0.6 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) UCMA PF17085.5 OWF43627.1 - 0.091 12.8 7.0 0.12 12.4 7.0 1.2 1 0 0 1 1 1 0 Unique cartilage matrix associated protein RNaseH_like PF04308.12 OWF43627.1 - 0.094 12.6 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 Ribonuclease H-like DnaJ PF00226.31 OWF43628.1 - 1.4e-17 63.5 0.3 1.9e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain Ig_3 PF13927.6 OWF43629.1 - 6.2e-30 103.6 10.2 1.6e-09 38.2 0.1 5.6 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 OWF43629.1 - 1.1e-21 76.7 1.2 6.5e-08 32.5 0.0 6.8 5 3 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF43629.1 - 2.6e-18 66.1 10.0 4.4e-05 23.7 0.1 5.0 5 0 0 5 5 5 4 Immunoglobulin domain C2-set_2 PF08205.12 OWF43629.1 - 1.9e-10 40.7 5.8 0.0054 16.8 0.2 5.3 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain ig PF00047.25 OWF43629.1 - 2e-10 40.7 10.4 0.00071 19.7 0.2 5.8 5 2 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 OWF43629.1 - 7.8e-06 26.0 0.9 0.015 15.5 0.0 4.3 3 1 1 4 4 4 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF43629.1 - 0.031 14.3 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain C2-set PF05790.15 OWF43629.1 - 0.13 12.5 0.3 6 7.1 0.0 3.4 4 0 0 4 4 4 0 Immunoglobulin C2-set domain OTU PF02338.19 OWF43630.1 - 2.3e-29 102.4 3.3 4.8e-29 101.4 0.0 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OWF43630.1 - 1.3e-06 28.1 7.0 0.0092 15.5 0.0 3.4 1 1 1 3 3 3 2 Peptidase C65 Otubain DUF3915 PF13054.6 OWF43630.1 - 0.014 15.4 2.8 0.014 15.4 2.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3915) Baculo_PEP_C PF04513.12 OWF43630.1 - 0.015 15.4 3.7 1.7 8.7 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 OWF43630.1 - 0.067 10.7 22.9 0.076 10.5 22.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 OWF43630.1 - 0.86 8.1 3.6 1 7.8 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 OWF43630.1 - 1.8 8.9 4.6 7.5 6.9 2.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DDHD PF02862.17 OWF43630.1 - 3.1 7.9 6.2 3.8 7.6 6.2 1.3 1 0 0 1 1 1 0 DDHD domain FUSC-like PF12805.7 OWF43630.1 - 5.5 6.0 6.6 19 4.2 0.2 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Spc7 PF08317.11 OWF43630.1 - 5.7 5.7 31.6 0.25 10.2 9.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Ank_2 PF12796.7 OWF43631.1 - 0.00019 21.9 0.2 0.00075 20.0 0.2 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF43631.1 - 0.02 15.4 0.0 0.27 11.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat BTB PF00651.31 OWF43632.1 - 1.2e-10 41.6 0.0 3.8e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Neur_chan_LBD PF02931.23 OWF43633.1 - 1.7e-57 194.3 4.5 2.4e-57 193.9 4.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF43633.1 - 2.9e-28 99.6 6.3 6.2e-28 98.5 6.3 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region WXG100 PF06013.12 OWF43633.1 - 0.19 12.0 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG CTD PF12815.7 OWF43634.1 - 1.8e-07 31.6 0.2 0.0012 19.3 0.6 2.5 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4222 PF13973.6 OWF43634.1 - 0.089 12.4 20.5 4.4 7.0 0.4 5.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4222) KduI PF04962.12 OWF43634.1 - 2.7 7.2 14.3 11 5.2 2.6 3.2 1 1 2 3 3 3 0 KduI/IolB family CTD PF12815.7 OWF43635.1 - 2.2e-08 34.6 1.3 0.0034 17.9 0.0 3.6 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4222 PF13973.6 OWF43635.1 - 1.4 8.6 22.9 2.6 7.7 0.1 6.4 4 2 3 7 7 7 0 Domain of unknown function (DUF4222) SF3b1 PF08920.10 OWF43635.1 - 2.8 8.5 11.5 25 5.4 0.2 4.7 1 1 3 4 4 4 0 Splicing factor 3B subunit 1 DUF4222 PF13973.6 OWF43636.1 - 9.8e-05 21.9 7.7 0.17 11.5 0.1 4.2 1 1 3 4 4 4 3 Domain of unknown function (DUF4222) KduI PF04962.12 OWF43636.1 - 2.3 7.5 4.0 5.5 6.2 1.8 2.5 1 1 2 3 3 3 0 KduI/IolB family Glyco_hydro81C PF17652.1 OWF43637.1 - 0.24 10.6 0.0 2 7.6 0.0 2.2 1 1 2 3 3 3 0 Glycosyl hydrolase family 81 C-terminal domain Pea-VEAacid PF08111.11 OWF43638.1 - 0.04 14.2 4.6 33 5.1 0.0 4.4 5 0 0 5 5 5 0 Pea-VEAacid family DUF3081 PF11280.8 OWF43638.1 - 0.1 12.4 0.1 1.8 8.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3081) GP52 PF17468.2 OWF43638.1 - 0.18 11.9 1.5 99 3.2 0.0 4.2 5 0 0 5 5 5 0 Phage gene product 52 Neur_chan_LBD PF02931.23 OWF43639.1 - 2.2e-62 210.3 2.0 3.2e-62 209.8 2.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF43639.1 - 2.3e-37 129.4 1.5 4.1e-37 128.5 1.5 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4223 PF13978.6 OWF43639.1 - 0.045 13.7 0.6 0.19 11.7 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) AvrB_AvrC PF05394.11 OWF43639.1 - 0.11 11.6 0.1 2.1 7.5 0.1 2.1 2 0 0 2 2 2 0 Avirulence protein DUF2304 PF10066.9 OWF43639.1 - 2.8 8.2 15.5 0.048 13.9 5.1 3.0 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) PQ-loop PF04193.14 OWF43640.1 - 1.9e-10 40.4 10.9 5e-10 39.0 1.3 2.9 3 0 0 3 3 3 2 PQ loop repeat MerC PF03203.14 OWF43640.1 - 0.81 10.2 8.6 0.13 12.7 1.0 2.4 2 1 0 2 2 2 0 MerC mercury resistance protein MtN3_slv PF03083.16 OWF43640.1 - 4.3 7.5 17.3 1.5 8.9 0.2 3.0 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange MORN PF02493.20 OWF43641.1 - 5.2e-37 123.6 82.4 1.7e-07 30.7 0.3 10.6 11 0 0 11 11 11 9 MORN repeat p25-alpha PF05517.12 OWF43641.1 - 0.0056 16.9 0.0 0.48 10.6 0.0 2.7 2 0 0 2 2 2 1 p25-alpha Cadherin_4 PF17803.1 OWF43641.1 - 0.03 15.0 0.5 0.03 15.0 0.5 2.1 2 0 0 2 2 2 0 Bacterial cadherin-like domain Pkinase_Tyr PF07714.17 OWF43642.1 - 1.9e-90 302.7 0.0 2.5e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF43642.1 - 5e-45 153.9 0.0 7.3e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OWF43642.1 - 0.0012 17.7 0.7 0.0024 16.7 0.6 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OWF43642.1 - 0.0037 16.6 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Laminin_EGF PF00053.24 OWF43642.1 - 0.0051 16.9 95.0 40 4.5 9.7 6.1 1 1 4 5 5 5 0 Laminin EGF domain APH PF01636.23 OWF43642.1 - 0.025 14.5 0.0 0.068 13.1 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DEFB136 PF17333.2 OWF43642.1 - 5.4 7.1 44.0 0.27 11.2 2.0 6.1 5 0 0 5 5 5 0 Beta defensin 136 Lipase PF00151.19 OWF43643.1 - 1.4e-88 297.4 0.0 1.6e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 Lipase Esterase PF00756.20 OWF43643.1 - 0.0001 22.1 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 OWF43643.1 - 0.00035 19.6 0.1 0.00052 19.0 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OWF43643.1 - 0.00064 18.8 0.0 0.00087 18.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 OWF43643.1 - 0.0017 19.0 0.7 0.0035 18.0 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 OWF43643.1 - 0.042 13.7 0.2 0.088 12.7 0.2 1.5 1 1 0 1 1 1 0 Lipase (class 3) Lipase PF00151.19 OWF43644.1 - 4e-74 249.9 0.0 4.5e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 OWF43644.1 - 0.0077 16.9 0.0 0.014 16.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 OWF43644.1 - 0.08 12.4 1.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 2) Palm_thioest PF02089.15 OWF43644.1 - 0.081 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase IlvGEDA_leader PF08046.11 OWF43644.1 - 1.1 8.8 2.9 2 7.9 2.9 1.4 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Lipase PF00151.19 OWF43645.1 - 8.5e-78 262.0 0.2 9.4e-78 261.8 0.2 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 OWF43645.1 - 0.048 14.3 0.2 0.059 14.0 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase PF00151.19 OWF43646.1 - 3e-35 122.1 0.7 3.7e-35 121.8 0.7 1.0 1 0 0 1 1 1 1 Lipase Lipase PF00151.19 OWF43647.1 - 1.2e-99 333.9 0.2 1.3e-99 333.7 0.2 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 OWF43647.1 - 2.2e-06 28.4 1.5 2.9e-06 28.1 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF43647.1 - 0.00026 20.7 0.5 0.00054 19.7 0.5 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 OWF43647.1 - 0.00042 19.9 0.5 0.00066 19.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 OWF43647.1 - 0.00061 19.7 0.8 0.0078 16.1 0.8 2.5 2 1 0 2 2 2 1 Serine hydrolase Lipase_2 PF01674.18 OWF43647.1 - 0.018 14.6 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) Palm_thioest PF02089.15 OWF43647.1 - 0.033 14.0 0.2 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 OWF43647.1 - 0.045 13.0 1.5 0.088 12.1 1.5 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 OWF43647.1 - 0.081 12.4 0.4 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase PF00151.19 OWF43648.1 - 4.8e-93 312.1 0.0 6e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_1 PF00561.20 OWF43648.1 - 0.00059 19.6 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF43648.1 - 0.00075 20.2 0.2 0.0014 19.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase PF00102.27 OWF43649.1 - 1.4e-129 430.6 5.6 4.4e-66 222.8 1.3 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF43649.1 - 9.1e-12 44.9 1.0 0.00022 21.1 0.0 3.3 3 1 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF43649.1 - 0.00058 19.9 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family DUF347 PF03988.12 OWF43649.1 - 0.031 14.5 0.5 0.065 13.4 0.5 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 OWF43649.1 - 0.074 13.9 0.0 0.19 12.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTPlike_phytase PF14566.6 OWF43649.1 - 0.13 12.4 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate Chordopox_A13L PF05961.11 OWF43649.1 - 0.14 12.4 0.1 0.82 9.9 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein WD40 PF00400.32 OWF43650.1 - 2.2e-54 180.2 22.3 2.5e-08 34.4 0.1 11.1 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF43650.1 - 9.1e-21 74.0 1.1 1.9e-05 24.8 0.0 8.2 4 3 6 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 OWF43650.1 - 1.2e-19 70.5 0.1 3.2e-19 69.2 0.1 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 OWF43650.1 - 2.2e-08 33.8 0.1 0.00034 20.0 0.0 4.0 4 1 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 OWF43650.1 - 1.1e-07 31.2 5.5 0.07 12.1 0.0 6.4 4 2 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF43650.1 - 0.00023 21.1 0.1 1.1 9.0 0.0 3.9 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 OWF43650.1 - 0.0072 16.2 0.0 5.3 7.1 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat Nup160 PF11715.8 OWF43650.1 - 0.013 14.2 4.3 0.94 8.0 0.1 4.6 4 2 1 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OWF43650.1 - 0.11 11.2 4.3 2.2 6.9 0.2 4.0 3 2 2 5 5 5 0 Nup133 N terminal like Eapp_C PF10238.9 OWF43650.1 - 0.37 10.9 4.3 0.64 10.1 0.6 3.2 4 0 0 4 4 4 0 E2F-associated phosphoprotein SAM_1 PF00536.30 OWF43651.1 - 3e-24 85.3 0.6 1.3e-08 35.2 0.0 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF43651.1 - 5.7e-23 80.8 0.2 7.2e-10 38.8 0.0 3.8 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 OWF43651.1 - 3.6e-10 39.4 0.0 8.5e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF43651.1 - 4.9e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF43651.1 - 0.0002 21.1 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain KxDL PF10241.9 OWF43651.1 - 0.043 14.1 0.6 0.11 12.7 0.6 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Cyt-b5 PF00173.28 OWF43652.1 - 2.4e-21 75.7 0.0 5.4e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 OWF43652.1 - 1.4e-11 44.6 0.0 8.2e-11 42.1 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain CS PF04969.16 OWF43652.1 - 0.00052 21.0 0.7 0.0012 19.8 0.7 1.7 1 0 0 1 1 1 1 CS domain SMN PF06003.12 OWF43652.1 - 6 6.1 6.2 12 5.0 6.2 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) LCAT PF02450.15 OWF43655.1 - 0.0014 17.9 0.1 0.0025 17.0 0.1 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF4369 PF14289.6 OWF43655.1 - 0.068 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Hydrolase_4 PF12146.8 OWF43655.1 - 0.11 11.7 0.2 0.25 10.6 0.1 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Dpy-30 PF05186.13 OWF43656.1 - 4.6e-18 64.6 0.4 3.6e-17 61.8 0.2 2.5 3 0 0 3 3 3 1 Dpy-30 motif ADK PF00406.22 OWF43656.1 - 1.4e-13 51.3 2.3 8.9e-08 32.4 0.2 3.6 3 1 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 OWF43656.1 - 1.7e-06 28.5 10.1 2.9e-06 27.7 0.3 3.6 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 OWF43656.1 - 1.9e-06 28.5 3.0 9.7e-06 26.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF43656.1 - 0.00018 21.9 0.0 0.00018 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF3987 PF13148.6 OWF43656.1 - 0.0013 17.9 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Hydin_ADK PF17213.3 OWF43656.1 - 0.0029 17.9 1.2 0.013 15.8 0.0 2.3 2 1 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 OWF43656.1 - 0.0034 17.5 0.0 0.0034 17.5 0.0 2.3 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 OWF43656.1 - 0.0062 16.6 0.1 0.15 12.2 0.0 3.1 3 1 0 3 3 3 1 50S ribosome-binding GTPase KTI12 PF08433.10 OWF43656.1 - 0.011 15.1 0.1 0.045 13.2 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 OWF43656.1 - 0.016 15.0 0.4 0.053 13.3 0.0 2.1 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 OWF43656.1 - 0.021 15.2 0.0 0.51 10.8 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF43656.1 - 0.022 14.7 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OWF43656.1 - 0.03 14.6 2.5 0.051 13.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OWF43656.1 - 0.049 13.5 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 OWF43656.1 - 0.057 13.7 0.7 0.34 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 OWF43656.1 - 0.061 13.4 0.9 1.2 9.2 0.0 3.2 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OWF43656.1 - 0.071 13.6 0.4 1.3 9.5 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 OWF43656.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 OWF43656.1 - 0.13 11.3 7.1 0.46 9.6 7.1 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.23 OWF43656.1 - 1.4 8.9 5.3 4 7.5 0.2 3.3 2 1 0 2 2 2 0 Dynamin family Vps16_C PF04840.12 OWF43657.1 - 3.9e-10 39.3 4.7 2.8e-05 23.3 0.3 2.7 3 0 0 3 3 3 2 Vps16, C-terminal region NOT2_3_5 PF04153.18 OWF43657.1 - 0.08 13.0 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family IL2 PF00715.17 OWF43657.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Interleukin 2 Pkinase PF00069.25 OWF43658.1 - 1.6e-80 270.3 0.0 2.1e-80 269.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF43658.1 - 1.3e-35 123.0 0.0 9.5e-34 116.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OWF43658.1 - 0.004 16.5 0.3 0.011 15.2 0.3 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF43658.1 - 0.014 14.4 0.0 0.027 13.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OWF43658.1 - 0.078 12.3 0.0 0.29 10.4 0.0 1.8 1 1 1 2 2 2 0 Kinase-like CNH PF00780.22 OWF43659.1 - 2.8e-69 233.8 0.2 4.1e-69 233.3 0.2 1.2 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 OWF43659.1 - 1.6e-61 208.0 0.0 3.8e-61 206.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF43659.1 - 8.7e-39 133.4 0.0 1.2e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF43659.1 - 0.00033 19.6 0.0 0.001 18.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OWF43659.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Homeodomain PF00046.29 OWF43660.1 - 9.4e-21 73.4 2.8 1.8e-20 72.5 2.8 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF43660.1 - 0.00011 21.6 0.1 0.00022 20.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez EF1G PF00647.19 OWF43661.1 - 2.5e-45 152.9 1.0 2.5e-45 152.9 1.0 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 OWF43661.1 - 6.2e-18 64.9 0.0 2.7e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF43661.1 - 1.5e-13 50.7 0.4 1.1e-12 47.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF43661.1 - 4.6e-07 29.8 0.0 8.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF43661.1 - 1.1e-05 25.5 2.8 0.00026 21.1 0.0 3.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF43661.1 - 1.4e-05 25.4 0.0 3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF43661.1 - 0.0025 18.1 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 OWF43661.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EF-hand_1 PF00036.32 OWF43662.1 - 8.7e-29 96.9 11.5 7.4e-07 28.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF43662.1 - 2.6e-25 88.7 4.1 9.3e-14 51.6 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF43662.1 - 2.5e-22 77.3 7.4 3e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF43662.1 - 5.2e-22 75.8 7.2 9.1e-06 25.2 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF43662.1 - 3.8e-19 68.3 7.7 8.9e-05 22.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF43662.1 - 1.8e-08 34.7 0.2 0.001 19.4 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF43662.1 - 7.9e-08 32.2 4.9 0.00087 19.2 0.4 3.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF43662.1 - 5.7e-05 23.4 1.3 0.024 14.9 0.0 3.4 3 1 0 3 3 3 1 EF-hand domain Caleosin PF05042.13 OWF43662.1 - 0.024 14.6 2.7 7.8 6.4 0.1 3.5 2 2 2 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 OWF43662.1 - 3 8.1 9.2 2.2 8.6 1.8 3.3 2 2 0 2 2 2 0 Dockerin type I domain ADP_PFK_GK PF04587.15 OWF43663.1 - 4.2e-149 496.7 0.0 4.8e-149 496.5 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region 7tm_1 PF00001.21 OWF43664.1 - 3.1e-55 187.4 16.2 3.8e-55 187.0 16.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF43664.1 - 5.3e-09 35.8 11.7 2.1e-08 33.9 11.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF43664.1 - 1.4e-05 24.5 16.9 3.2e-05 23.4 16.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 OWF43664.1 - 0.00029 20.7 18.0 0.00093 19.0 18.0 1.8 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF43664.1 - 0.00046 19.9 19.8 0.00056 19.6 16.6 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF202 PF02656.15 OWF43664.1 - 0.09 13.2 2.1 0.42 11.1 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pox_LP_H2 PF03356.15 OWF43664.1 - 0.12 12.2 1.0 0.34 10.7 0.6 2.1 2 0 0 2 2 2 0 Viral late protein H2 DUF2157 PF09925.9 OWF43664.1 - 0.58 9.9 8.4 0.081 12.7 3.1 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) PEP_mutase PF13714.6 OWF43665.1 - 9.5e-71 238.0 0.0 1.2e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OWF43665.1 - 0.00073 18.1 0.1 0.0093 14.5 0.0 2.2 1 1 1 2 2 2 1 Isocitrate lyase family Herpes_UL14 PF03580.14 OWF43665.1 - 0.054 13.8 0.4 7.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Toprim_3 PF13362.6 OWF43665.1 - 0.086 13.2 0.2 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Toprim domain DUF2462 PF09495.10 OWF43667.1 - 5.6e-15 55.8 12.1 5.6e-15 55.8 12.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) SAM_2 PF07647.17 OWF43668.1 - 8.1e-24 83.5 0.3 7.4e-11 42.0 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF43668.1 - 1e-17 64.3 1.2 2.1e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 OWF43668.1 - 1.2e-11 45.2 0.0 3.9e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 TIR domain SAM_PNT PF02198.16 OWF43668.1 - 0.0028 17.6 0.0 0.0076 16.2 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HEAT_EZ PF13513.6 OWF43668.1 - 0.019 15.4 0.1 1.4 9.5 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat V-ATPase_H_C PF11698.8 OWF43668.1 - 0.023 14.8 0.0 4.9 7.3 0.0 2.8 2 0 0 2 2 2 0 V-ATPase subunit H SAM_3 PF18016.1 OWF43668.1 - 0.029 14.2 0.0 0.14 12.0 0.0 2.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HEAT_2 PF13646.6 OWF43668.1 - 0.057 13.8 0.1 6.5 7.2 0.0 3.3 3 0 0 3 3 3 0 HEAT repeats 7tm_1 PF00001.21 OWF43669.1 - 5.2e-38 130.9 20.4 6.7e-38 130.5 20.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SNF5 PF04855.12 OWF43671.1 - 1.4e-39 136.4 0.4 3.6e-24 85.9 0.2 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 SIX1_SD PF16878.5 OWF43672.1 - 1.2e-17 64.4 0.1 2.9e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeobox_KN PF05920.11 OWF43672.1 - 1.1e-16 60.4 1.0 2.4e-16 59.3 1.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF43672.1 - 1e-10 41.3 1.0 5.3e-10 39.0 0.8 2.3 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 OWF43672.1 - 0.036 13.5 0.1 0.19 11.2 0.0 2.3 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez zf-B_box PF00643.24 OWF43673.1 - 5.2e-09 36.1 2.5 1.1e-08 35.1 2.5 1.5 1 0 0 1 1 1 1 B-box zinc finger T3SS_needle_E PF08988.10 OWF43673.1 - 0.036 14.2 2.6 1.8 8.8 0.1 2.5 1 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle APG6_N PF17675.1 OWF43673.1 - 0.062 13.8 7.2 0.14 12.7 7.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 OWF43673.1 - 0.096 12.2 3.9 0.14 11.7 3.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lectin_N PF03954.14 OWF43673.1 - 0.16 11.7 6.9 0.31 10.8 6.9 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Fzo_mitofusin PF04799.13 OWF43673.1 - 0.16 11.5 9.6 1.1 8.8 9.6 2.0 1 1 0 1 1 1 0 fzo-like conserved region IMD PF08397.11 OWF43673.1 - 0.45 9.9 7.7 0.85 9.0 7.7 1.5 1 1 0 1 1 1 0 IRSp53/MIM homology domain DUF3854 PF12965.7 OWF43673.1 - 0.54 10.2 5.4 2.5 8.1 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3854) Streptin-Immun PF11083.8 OWF43673.1 - 0.55 10.7 5.0 0.23 11.9 0.7 2.2 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Syntaxin-6_N PF09177.11 OWF43674.1 - 6.6e-05 23.4 1.8 6.6e-05 23.4 1.8 2.1 1 1 2 3 3 3 1 Syntaxin 6, N-terminal GP3_package PF16677.5 OWF43674.1 - 0.0041 17.2 0.6 0.0074 16.4 0.4 1.4 1 1 0 1 1 1 1 DNA-packaging protein gp3 ExsD PF16806.5 OWF43674.1 - 0.012 15.5 3.1 0.016 15.1 3.1 1.1 1 0 0 1 1 1 0 Antiactivator protein ExsD UBN_AB PF14075.6 OWF43674.1 - 0.02 14.6 4.8 0.026 14.2 4.8 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain ING PF12998.7 OWF43674.1 - 0.023 15.3 9.0 0.085 13.5 1.0 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CPG4 PF15481.6 OWF43674.1 - 0.042 14.5 1.2 0.07 13.8 1.2 1.4 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 FapA PF03961.13 OWF43674.1 - 0.1 11.2 3.8 0.12 10.9 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CC2-LZ PF16516.5 OWF43674.1 - 0.13 12.7 9.7 2.2 8.7 0.3 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMPIT PF07851.13 OWF43674.1 - 0.23 10.7 11.3 0.023 14.0 3.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF4363 PF14276.6 OWF43674.1 - 0.24 11.5 6.5 2.5 8.3 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DUF4407 PF14362.6 OWF43674.1 - 0.31 10.4 3.3 0.35 10.2 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 OWF43674.1 - 0.35 10.6 2.9 0.19 11.5 0.6 1.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CdvA PF18822.1 OWF43674.1 - 0.37 10.6 7.1 0.26 11.1 1.8 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain LMP PF04778.12 OWF43674.1 - 0.63 9.9 8.6 0.21 11.5 1.1 2.2 1 1 0 2 2 2 0 LMP repeated region Prefoldin_2 PF01920.20 OWF43674.1 - 0.7 9.9 9.8 0.5 10.4 1.5 2.5 2 1 0 2 2 2 0 Prefoldin subunit LMBR1 PF04791.16 OWF43674.1 - 0.76 8.6 4.8 0.88 8.4 4.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein GRDP-like PF07173.12 OWF43674.1 - 0.78 10.4 4.6 2.2 8.9 4.6 1.8 1 1 0 1 1 1 0 Glycine-rich domain-containing protein-like CENP-Q PF13094.6 OWF43674.1 - 1.2 9.3 7.9 0.29 11.3 3.5 1.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Plk4_PB2 PF18409.1 OWF43674.1 - 2.1 9.0 6.1 16 6.3 6.1 2.0 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 OmpH PF03938.14 OWF43674.1 - 2.7 8.3 9.8 0.6 10.4 3.0 2.2 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) NIPSNAP PF07978.13 OWF43675.1 - 7.1e-40 135.4 0.0 3.1e-28 98.0 0.0 2.4 2 0 0 2 2 2 2 NIPSNAP DUF4200 PF13863.6 OWF43676.1 - 7e-36 123.2 33.2 7e-36 123.2 33.2 2.9 2 1 0 3 3 3 1 Domain of unknown function (DUF4200) DUF3450 PF11932.8 OWF43676.1 - 0.0021 17.4 4.2 0.0021 17.4 4.2 3.7 1 1 3 4 4 4 2 Protein of unknown function (DUF3450) CUB PF00431.20 OWF43677.1 - 8.7e-16 58.2 0.2 1.7e-15 57.3 0.2 1.4 1 0 0 1 1 1 1 CUB domain SID-1_RNA_chan PF13965.6 OWF43677.1 - 0.0034 15.9 0.0 0.0041 15.6 0.0 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF3377 PF11857.8 OWF43677.1 - 0.12 12.4 0.5 0.35 10.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) HNF-1A_C PF04813.12 OWF43677.1 - 0.3 11.9 3.5 0.27 12.0 1.7 1.8 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus zf-B_box PF00643.24 OWF43678.1 - 1.3e-12 47.6 22.3 1.6e-07 31.4 8.9 2.7 2 0 0 2 2 2 2 B-box zinc finger SGL PF08450.12 OWF43678.1 - 0.012 15.3 0.5 5 6.6 0.0 3.3 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Lectin_N PF03954.14 OWF43678.1 - 0.084 12.6 3.4 0.2 11.4 3.4 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 OWF43678.1 - 0.2 11.7 8.0 0.2 11.7 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-B_box PF00643.24 OWF43679.1 - 1e-07 32.0 20.8 0.00048 20.2 2.2 2.4 2 0 0 2 2 2 2 B-box zinc finger UPF0102 PF02021.17 OWF43679.1 - 0.0049 17.1 2.8 1.7 8.9 0.0 2.6 3 0 0 3 3 3 2 Uncharacterised protein family UPF0102 EAP30 PF04157.16 OWF43679.1 - 0.02 14.2 0.7 0.031 13.6 0.7 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family DUF1664 PF07889.12 OWF43679.1 - 0.16 12.0 7.1 0.15 12.1 5.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mnd1 PF03962.15 OWF43679.1 - 0.33 11.3 3.4 9.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Mnd1 HTH domain AHSA1 PF08327.11 OWF43680.1 - 0.013 15.7 12.3 0.94 9.7 1.5 4.6 1 1 2 4 4 4 0 Activator of Hsp90 ATPase homolog 1-like protein DUF2583 PF10762.9 OWF43680.1 - 0.64 10.5 20.2 48 4.5 0.1 8.8 1 1 11 12 12 12 0 Protein of unknown function (DUF2583) DUF333 PF03891.15 OWF43680.1 - 1.2 9.4 23.2 1.4e+02 2.7 0.1 8.5 2 2 10 12 12 12 0 Domain of unknown function (DUF333) zf-B_box PF00643.24 OWF43681.1 - 2e-11 43.8 29.0 2.3e-07 30.8 9.0 2.9 3 0 0 3 3 3 2 B-box zinc finger SGL PF08450.12 OWF43681.1 - 0.0018 17.9 1.5 1.2 8.6 0.0 3.2 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Peptidase_M15_2 PF05951.13 OWF43681.1 - 0.1 12.3 3.8 0.82 9.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) Apolipoprotein PF01442.18 OWF43681.1 - 0.18 11.7 6.6 0.25 11.2 6.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NHL PF01436.21 OWF43681.1 - 0.87 9.7 6.0 49 4.2 0.3 4.0 4 0 0 4 4 4 0 NHL repeat Siva PF05458.12 OWF43681.1 - 2.3 7.9 14.7 2.1 8.0 3.7 2.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Gp-FAR-1 PF05823.12 OWF43681.1 - 2.7 8.4 9.3 22 5.4 9.3 2.1 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1664 PF07889.12 OWF43681.1 - 2.8 8.0 15.0 0.97 9.5 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1003 PF06210.11 OWF43681.1 - 2.9 8.1 4.4 1.6 8.9 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) LMBR1 PF04791.16 OWF43681.1 - 5.4 5.8 4.9 7 5.4 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-B_box PF00643.24 OWF43682.1 - 2.6e-10 40.3 30.1 9.4e-07 28.9 9.3 3.2 3 0 0 3 3 3 2 B-box zinc finger Reg_prop PF07494.11 OWF43682.1 - 0.035 14.3 0.7 0.19 12.1 0.0 2.7 3 0 0 3 3 3 0 Two component regulator propeller DUF2576 PF10845.8 OWF43682.1 - 0.079 12.6 0.3 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) NHL PF01436.21 OWF43682.1 - 0.26 11.4 6.4 32 4.8 0.0 4.4 4 0 0 4 4 4 0 NHL repeat DUF1664 PF07889.12 OWF43682.1 - 0.95 9.5 6.9 0.52 10.4 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-B_box PF00643.24 OWF43683.1 - 4.5e-07 29.9 32.6 0.0002 21.5 6.6 2.7 3 0 0 3 3 3 2 B-box zinc finger RRF PF01765.19 OWF43683.1 - 0.0004 20.4 3.3 0.0006 19.8 3.3 1.4 1 0 0 1 1 1 1 Ribosome recycling factor Nas2_N PF18265.1 OWF43683.1 - 0.46 10.4 7.0 0.17 11.8 0.8 3.0 3 1 0 3 3 3 0 Nas2 N_terminal domain DUF1003 PF06210.11 OWF43683.1 - 1.7 8.8 3.6 1.7 8.8 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) DDE_Tnp_4 PF13359.6 OWF43684.1 - 6.5e-54 181.9 0.1 2.4e-53 180.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease THAP PF05485.12 OWF43684.1 - 4.5e-09 37.1 0.1 1.3e-08 35.7 0.1 1.8 1 0 0 1 1 1 1 THAP domain HTH_Tnp_4 PF13613.6 OWF43684.1 - 4.9e-09 35.8 0.1 1e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OWF43684.1 - 0.0017 18.1 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain HTH_3 PF01381.22 OWF43684.1 - 0.0018 18.3 0.0 3.4 7.8 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix TSP_1 PF00090.19 OWF43685.1 - 4.6e-19 68.4 18.7 1.5e-11 44.3 6.0 3.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain DAG1 PF05454.11 OWF43685.1 - 0.0016 17.9 0.2 0.0022 17.4 0.2 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) MFS_1 PF07690.16 OWF43686.1 - 2.9e-08 33.0 13.4 3.8e-08 32.7 13.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF43687.1 - 5e-09 35.5 18.3 6.2e-08 31.9 18.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OWF43687.1 - 0.0048 15.3 0.4 1.8 6.8 0.0 2.2 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF43688.1 - 2.4e-22 79.4 35.1 3.8e-14 52.4 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OWF43688.1 - 3e-15 56.4 7.6 3e-15 56.4 7.6 2.3 1 1 0 2 2 2 1 Nodulin-like CopK PF11525.8 OWF43689.1 - 0.032 13.9 0.0 20 4.9 0.0 3.6 2 2 0 2 2 2 0 Copper resistance protein K Prefoldin_2 PF01920.20 OWF43689.1 - 0.55 10.2 2.3 88 3.1 0.0 3.8 4 0 0 4 4 4 0 Prefoldin subunit DUF2534 PF10749.9 OWF43689.1 - 4.4 7.5 10.8 19 5.5 1.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2534) HH_signal PF01085.18 OWF43690.1 - 4.6e-81 270.2 0.0 6.6e-81 269.7 0.0 1.2 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Hint PF01079.20 OWF43690.1 - 9.1e-68 228.0 0.0 1.2e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Hint module Peptidase_M15_3 PF08291.11 OWF43690.1 - 0.00026 21.0 0.1 0.00043 20.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase M15 tRNA_m1G_MT PF01746.21 OWF43690.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Hint_2 PF13403.6 OWF43690.1 - 0.12 12.6 0.4 0.25 11.6 0.1 1.6 2 0 0 2 2 2 0 Hint domain MFS_1 PF07690.16 OWF43691.1 - 4e-31 108.2 17.7 4e-31 108.2 17.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 OWF43691.1 - 7.8e-18 64.9 7.5 7.8e-18 64.9 7.5 2.5 2 1 1 3 3 3 1 Nodulin-like Ribonuc_2-5A PF06479.12 OWF43691.1 - 0.069 13.3 0.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A MFS_1_like PF12832.7 OWF43691.1 - 0.3 9.9 18.2 0.7 8.7 9.7 2.6 1 1 1 2 2 2 0 MFS_1 like family CbtA PF09490.10 OWF43691.1 - 4.7 6.9 7.9 0.6 9.8 1.7 2.7 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) SPC25 PF06703.11 OWF43691.1 - 9.8 5.9 14.1 0.37 10.6 5.3 2.8 3 1 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MIP-T3 PF10243.9 OWF43692.1 - 1.4e-47 160.3 0.8 3.6e-47 159.0 0.8 1.7 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 OWF43692.1 - 3e-47 160.4 15.7 3e-47 160.4 15.7 3.3 3 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 OWF43692.1 - 0.12 12.6 10.0 0.16 12.1 6.9 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Mito_carr PF00153.27 OWF43693.1 - 1.6e-68 226.7 2.0 5e-23 80.9 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF43693.1 - 0.045 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Tetraspanin PF00335.20 OWF43694.1 - 1.1e-24 87.5 15.2 1.8e-24 86.8 15.2 1.3 1 0 0 1 1 1 1 Tetraspanin family LRR_8 PF13855.6 OWF43695.1 - 1.2e-20 73.0 21.4 1e-07 31.6 3.0 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OWF43695.1 - 4.3e-16 58.7 22.3 3.9e-07 30.3 6.1 5.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF43695.1 - 5.3e-07 29.3 15.7 2.4 9.0 0.2 7.0 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 OWF43695.1 - 0.0003 20.4 11.1 0.044 13.3 0.3 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 OWF43695.1 - 0.00032 20.5 19.8 8.6 6.7 0.1 7.1 7 0 0 7 7 7 3 Leucine Rich repeat RsmF_methylt_CI PF17126.5 OWF43695.1 - 0.089 12.8 0.0 18 5.4 0.0 3.1 2 1 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain WD40 PF00400.32 OWF43696.1 - 8.1e-51 168.9 33.9 1.3e-10 41.7 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF43696.1 - 4.1e-20 71.9 6.6 0.0004 20.6 0.1 6.6 1 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF43696.1 - 2.1e-08 34.3 2.2 4e-05 23.6 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF43696.1 - 0.00015 20.8 3.0 0.39 9.6 0.1 4.5 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 OWF43696.1 - 0.018 13.1 3.2 0.084 10.9 0.4 2.7 2 1 1 3 3 3 0 IKI3 family Myosin_N PF02736.19 OWF43696.1 - 0.025 14.4 4.3 0.62 10.0 0.1 2.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain DUF736 PF05284.12 OWF43696.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF736) zf-B_box PF00643.24 OWF43697.1 - 2.2e-07 30.9 3.5 5.2e-07 29.7 3.5 1.6 1 0 0 1 1 1 1 B-box zinc finger SGL PF08450.12 OWF43697.1 - 7.4e-05 22.4 0.2 0.57 9.7 0.0 3.5 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF43697.1 - 0.00034 20.5 0.1 1.6 9.2 0.1 4.4 4 0 0 4 4 4 1 Two component regulator propeller DUF3095 PF11294.8 OWF43697.1 - 0.013 14.5 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) Pilin_N PF07790.11 OWF43697.1 - 0.032 15.2 0.3 0.089 13.7 0.3 1.8 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal WD40 PF00400.32 OWF43697.1 - 0.041 14.8 0.9 23 6.1 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Peptidase_S46 PF10459.9 OWF43697.1 - 0.088 11.4 0.4 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Peptidase S46 SUKH-4 PF14435.6 OWF43697.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 SUKH-4 immunity protein PRANC PF09372.10 OWF43697.1 - 0.18 12.2 2.3 1.1 9.7 0.3 2.6 3 0 0 3 3 3 0 PRANC domain NHL PF01436.21 OWF43697.1 - 8.3 6.7 9.5 42 4.4 0.6 5.0 5 0 0 5 5 5 0 NHL repeat DUF3631 PF12307.8 OWF43698.1 - 0.00067 19.9 0.4 0.00075 19.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3631) PLU-1 PF08429.11 OWF43698.1 - 0.0033 16.7 2.6 0.0035 16.6 1.8 1.4 2 0 0 2 2 2 1 PLU-1-like protein ArAE_1_C PF11728.8 OWF43698.1 - 0.011 15.7 1.1 0.47 10.4 0.0 2.0 1 1 1 2 2 2 0 Putative aromatic acid exporter C-terminal domain IMD PF08397.11 OWF43698.1 - 0.028 13.8 0.4 0.039 13.3 0.4 1.3 1 1 0 1 1 1 0 IRSp53/MIM homology domain CCDC66 PF15236.6 OWF43698.1 - 0.031 14.1 1.8 0.042 13.7 1.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF4071 PF13281.6 OWF43698.1 - 0.032 13.3 2.2 0.038 13.1 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DASH_Dad4 PF08650.10 OWF43698.1 - 0.13 12.3 0.8 0.2 11.6 0.8 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad4 DUF2155 PF09923.9 OWF43698.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF349 PF03993.12 OWF43698.1 - 0.17 12.2 1.0 0.23 11.8 1.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) EF-G-binding_N PF07299.11 OWF43698.1 - 0.19 12.3 1.8 1.1 9.9 0.3 2.2 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal MobC PF05713.11 OWF43698.1 - 0.2 12.2 0.8 1 9.9 0.1 2.3 2 1 0 2 2 2 0 Bacterial mobilisation protein (MobC) DUF4320 PF14208.6 OWF43699.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Mab-21 PF03281.14 OWF43699.1 - 0.018 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Mab-21 protein Costars PF14705.6 OWF43700.1 - 2.7e-25 88.3 0.1 3.2e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 Costars PID_2 PF14719.6 OWF43701.1 - 5.2e-07 29.7 0.0 9.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) EPL1 PF10513.9 OWF43701.1 - 0.007 16.8 4.6 0.011 16.1 4.6 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like CDC45 PF02724.14 OWF43701.1 - 0.22 9.8 7.1 0.26 9.5 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 OWF43701.1 - 0.26 10.1 8.8 0.18 10.7 6.8 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.17 OWF43701.1 - 0.37 9.5 1.7 0.41 9.4 1.7 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 OWF43701.1 - 0.4 9.1 7.4 0.62 8.5 7.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 Rsc14 PF08586.10 OWF43701.1 - 1.9 9.4 4.9 5.8 7.8 0.1 2.9 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit GtrA PF04138.14 OWF43702.1 - 0.0015 18.7 4.8 0.0015 18.7 4.8 2.2 2 0 0 2 2 2 1 GtrA-like protein Bax1-I PF01027.20 OWF43702.1 - 0.0023 17.8 25.4 0.0023 17.8 25.4 1.6 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FXa_inhibition PF14670.6 OWF43703.1 - 1.1e-13 51.1 61.1 5.5e-07 29.8 7.7 4.7 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site SKG6 PF08693.10 OWF43703.1 - 1.3e-05 24.5 2.7 2.8e-05 23.4 2.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ldl_recept_b PF00058.17 OWF43703.1 - 5.5e-05 23.6 9.3 3.7 8.1 0.4 5.9 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B SGL PF08450.12 OWF43703.1 - 0.0033 17.0 1.9 21 4.6 0.0 5.3 5 1 0 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region OLF PF02191.16 OWF43703.1 - 0.037 13.6 0.4 4.3 6.8 0.0 3.2 3 0 0 3 3 3 0 Olfactomedin-like domain Sushi PF00084.20 OWF43703.1 - 0.063 13.9 23.8 0.045 14.3 1.4 4.8 4 1 0 4 4 4 0 Sushi repeat (SCR repeat) cEGF PF12662.7 OWF43703.1 - 1.9 8.5 25.3 0.049 13.6 2.3 4.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like PNMA PF14893.6 OWF43704.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.2 1 1 0 1 1 1 1 PNMA FXa_inhibition PF14670.6 OWF43705.1 - 1.6e-16 60.3 38.8 1.3e-08 34.9 5.5 6.5 8 0 0 8 8 8 3 Coagulation Factor Xa inhibitory site Sushi PF00084.20 OWF43705.1 - 1.5e-14 54.3 41.7 0.0011 19.6 1.5 6.7 5 1 1 6 6 6 5 Sushi repeat (SCR repeat) Ldl_recept_b PF00058.17 OWF43705.1 - 2e-10 41.0 3.1 0.039 14.4 0.0 6.7 6 1 0 6 6 6 4 Low-density lipoprotein receptor repeat class B SGL PF08450.12 OWF43705.1 - 2.3e-08 33.9 0.4 0.019 14.6 0.0 4.2 4 1 1 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OWF43705.1 - 0.00028 21.0 0.2 11 6.3 0.0 5.3 4 1 1 5 5 5 2 Arylesterase cEGF PF12662.7 OWF43705.1 - 0.0038 17.1 0.9 0.0038 17.1 0.9 6.2 5 0 0 5 5 5 1 Complement Clr-like EGF-like SKG6 PF08693.10 OWF43705.1 - 0.015 14.7 0.2 0.03 13.7 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Str_synth PF03088.16 OWF43705.1 - 0.02 15.0 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 0 Strictosidine synthase Actin PF00022.19 OWF43706.1 - 1.1e-152 508.4 0.0 3.5e-152 506.7 0.0 1.6 1 1 0 1 1 1 1 Actin DNase_II PF03265.15 OWF43708.1 - 8.7e-102 340.7 2.0 1.1e-101 340.4 2.0 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II FKBP_C PF00254.28 OWF43709.1 - 9.5e-29 99.6 0.4 2.5e-28 98.2 0.1 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 OWF43709.1 - 4.9e-06 26.5 0.2 1.2e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 WH1 domain DNA_pol_phi PF04931.13 OWF43709.1 - 0.0021 16.2 22.4 0.0021 16.2 22.4 4.6 3 2 0 3 3 3 1 DNA polymerase phi VID27_PH PF17747.1 OWF43709.1 - 0.027 14.7 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 VID27 PH-like domain DUF3568 PF12092.8 OWF43709.1 - 0.044 13.8 3.4 0.13 12.3 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) SH3_1 PF00018.28 OWF43711.1 - 3.1 7.5 5.6 58 3.4 0.0 3.5 3 1 0 4 4 4 0 SH3 domain Metallophos PF00149.28 OWF43712.1 - 2.9e-33 116.1 0.0 4.1e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M16 PF00675.20 OWF43713.1 - 9.3e-37 126.3 0.0 1.8e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OWF43713.1 - 8e-26 91.2 0.0 9.4e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain RINGv PF12906.7 OWF43714.1 - 3.2e-12 46.4 11.4 3.2e-12 46.4 11.4 2.1 2 0 0 2 2 2 1 RING-variant domain EGF_Tenascin PF18720.1 OWF43714.1 - 0.99 9.5 9.2 3.8 7.7 9.2 2.1 1 0 0 1 1 1 0 Tenascin EGF domain FANCL_C PF11793.8 OWF43714.1 - 1.6 8.9 12.4 0.64 10.2 8.2 2.6 2 1 1 3 3 3 0 FANCL C-terminal domain Endonuclease_NS PF01223.23 OWF43715.1 - 3.5e-43 148.0 1.2 5e-43 147.5 1.2 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 OWF43715.1 - 0.083 13.0 0.3 0.36 10.9 0.3 1.9 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease TFIIB PF00382.19 OWF43716.1 - 1.8e-50 168.8 2.1 2.6e-27 94.6 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OWF43716.1 - 4.2e-11 42.2 0.1 7.2e-11 41.4 0.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OWF43716.1 - 9.8e-07 28.6 0.1 7.7e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain RB_B PF01857.20 OWF43716.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 OWF43716.1 - 0.00055 20.0 0.2 0.47 10.6 0.0 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 OWF43716.1 - 0.091 12.3 0.1 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 OB_NTP_bind PF07717.16 OWF43717.1 - 1.7e-15 57.1 0.1 2.6e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RRM_5 PF13893.6 OWF43717.1 - 0.13 11.9 0.1 0.32 10.6 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cor1 PF04803.12 OWF43718.1 - 2.4e-50 170.2 26.3 2.4e-50 170.2 26.3 1.7 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region Reoviridae_Vp9 PF08978.10 OWF43718.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Reoviridae VP9 Tox-ODYAM1 PF15642.6 OWF43718.1 - 0.2 10.6 10.0 0.18 10.8 9.0 1.4 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus LMF1 PF06762.14 OWF43719.1 - 2e-157 524.8 21.1 2.4e-157 524.6 21.1 1.1 1 0 0 1 1 1 1 Lipase maturation factor CNDH2_C PF16858.5 OWF43720.1 - 2.2e-71 241.1 5.2 2.2e-71 241.1 5.2 2.6 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 OWF43720.1 - 6.9e-44 148.6 0.6 6.9e-44 148.6 0.6 2.5 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.5 OWF43720.1 - 1.9e-11 44.8 3.5 1.9e-11 44.8 3.5 3.3 3 1 0 3 3 3 1 PF16858 PP1c_bdg PF10488.9 OWF43722.1 - 3e-11 43.4 0.8 3.3e-11 43.2 0.8 1.2 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region PP1c_bdg PF10488.9 OWF43723.1 - 0.0022 17.5 31.7 0.96 8.9 31.7 3.7 1 1 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region zf-RING_4 PF14570.6 OWF43724.1 - 5.9e-20 70.8 12.3 1e-19 70.0 12.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OWF43724.1 - 7.9e-06 25.6 8.4 1.6e-05 24.7 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 OWF43724.1 - 9.2e-05 22.2 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 OWF43724.1 - 0.0015 19.2 0.1 0.0064 17.2 0.1 2.1 1 0 0 1 1 1 1 Torus domain zf-RING_2 PF13639.6 OWF43724.1 - 0.0064 16.8 11.2 0.0064 16.8 11.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.6 OWF43724.1 - 0.011 15.9 2.8 0.025 14.7 2.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 OWF43724.1 - 0.024 14.5 10.4 0.06 13.2 10.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF43724.1 - 0.034 14.0 9.9 0.073 13.0 9.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.6 OWF43724.1 - 0.037 14.0 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Vasculin PF15337.6 OWF43724.1 - 0.12 13.2 0.0 0.12 13.2 0.0 2.6 3 0 0 3 3 2 0 Vascular protein family Vasculin-like 1 Prok-RING_4 PF14447.6 OWF43724.1 - 0.58 10.1 9.3 17 5.3 9.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 OWF43724.1 - 1.2 9.1 3.8 2.9 7.8 3.8 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-SCNM1 PF15803.5 OWF43725.1 - 4.1e-16 58.3 2.2 7e-16 57.6 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 SCNM1_acidic PF15805.5 OWF43725.1 - 2.8e-15 55.8 1.1 6.8e-15 54.5 1.1 1.7 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DUF2120 PF09893.9 OWF43725.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) P35 PF02331.15 OWF43725.1 - 0.031 13.6 0.5 0.031 13.6 0.5 1.4 2 0 0 2 2 2 0 Apoptosis preventing protein zf-C2H2_4 PF13894.6 OWF43726.1 - 4.2e-52 170.3 302.9 0.00098 19.8 0.9 39.1 39 0 0 39 39 39 29 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF43726.1 - 5.9e-45 149.3 298.8 0.00015 22.0 1.1 37.5 38 0 0 38 38 38 26 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43726.1 - 9.6e-13 47.9 284.3 8.5e-05 22.8 0.1 36.9 41 0 0 41 41 41 16 Zinc-finger double domain zf-met PF12874.7 OWF43726.1 - 0.00065 20.0 197.7 0.11 13.0 1.5 29.0 29 0 0 29 29 29 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF43726.1 - 0.0014 18.6 3.4 0.0068 16.4 1.7 30.9 37 0 0 37 37 37 10 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF43726.1 - 0.019 14.7 0.1 0.019 14.7 0.1 23.0 27 0 0 27 27 27 0 zinc-finger C2H2-type Arc_trans_TRASH PF08394.10 OWF43726.1 - 0.038 14.3 0.3 0.038 14.3 0.3 13.8 14 1 0 14 14 14 0 Archaeal TRASH domain zf-WRNIP1_ubi PF18279.1 OWF43726.1 - 1.4 9.7 14.5 2.6e+02 2.6 0.4 8.4 6 0 0 6 6 6 0 Werner helicase-interacting protein 1 ubiquitin-binding domain FMO-like PF00743.19 OWF43727.1 - 2e-73 247.6 0.1 1.8e-52 178.5 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OWF43727.1 - 7.6e-15 54.9 0.0 1.6e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF43727.1 - 3e-14 53.0 0.7 4e-09 36.2 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF43727.1 - 2.4e-09 36.8 0.1 1.3e-05 24.6 0.0 3.0 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OWF43727.1 - 1.2e-05 25.8 0.1 0.00055 20.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF43727.1 - 1.8e-05 24.9 0.0 6.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OWF43727.1 - 1.9e-05 24.7 0.0 5.8e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OWF43727.1 - 4.6e-05 23.2 0.1 0.025 14.2 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase DUF1188 PF06690.11 OWF43727.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Neur_chan_LBD PF02931.23 OWF43728.1 - 4.5e-48 163.6 2.5 8.1e-48 162.7 2.5 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF43728.1 - 8.3e-23 81.7 8.1 8.3e-23 81.7 8.1 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region MRAP PF15183.6 OWF43729.1 - 0.012 15.5 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family EGF PF00008.27 OWF43729.1 - 6.4 7.2 18.9 0.054 13.8 8.2 2.5 2 1 0 2 2 2 0 EGF-like domain PRIMA1 PF16101.5 OWF43730.1 - 0.0028 17.7 0.4 0.0028 17.7 0.4 2.0 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 EGF PF00008.27 OWF43730.1 - 0.093 13.1 13.2 0.078 13.3 6.0 2.7 2 0 0 2 2 2 0 EGF-like domain EphA2_TM PF14575.6 OWF43730.1 - 0.3 12.0 1.6 1.1 10.2 0.4 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NNMT_PNMT_TEMT PF01234.17 OWF43731.1 - 2.1e-51 174.6 0.0 2.4e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 OWF43731.1 - 0.00036 21.2 0.0 0.00083 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF43731.1 - 0.00047 20.8 0.0 0.066 13.9 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF43731.1 - 0.00074 19.4 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF43731.1 - 0.0019 18.8 0.0 0.011 16.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF43731.1 - 0.0022 17.8 0.0 0.15 11.8 0.0 2.8 2 1 1 3 3 3 1 Methyltransferase domain N2227 PF07942.12 OWF43731.1 - 0.0033 16.7 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Ubie_methyltran PF01209.18 OWF43731.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 OWF43731.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 OWF43732.1 - 2.8e-57 193.9 0.0 3.3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 OWF43732.1 - 1.5e-07 31.4 0.0 5.8e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF43732.1 - 8.9e-06 25.6 0.0 0.00043 20.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF43732.1 - 9.4e-06 26.2 0.0 0.00047 20.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF43732.1 - 1.5e-05 25.7 0.1 0.00013 22.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF43732.1 - 0.00011 22.8 0.0 0.53 11.0 0.0 3.3 3 1 1 4 4 4 2 Methyltransferase domain NodS PF05401.11 OWF43732.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) UPAR_LY6_2 PF16975.5 OWF43733.1 - 1.5e-22 79.8 14.4 2.1e-22 79.3 14.4 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 SNARE PF05739.19 OWF43734.1 - 1e-05 25.4 0.4 2.5e-05 24.2 0.4 1.7 1 0 0 1 1 1 1 SNARE domain Spc7 PF08317.11 OWF43734.1 - 0.017 14.0 6.4 0.041 12.8 0.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.16 OWF43734.1 - 0.019 15.2 1.4 0.019 15.2 1.4 2.5 2 1 1 3 3 3 0 Flagellar FliJ protein Goodbye PF17109.5 OWF43734.1 - 0.02 15.3 0.8 1.6 9.2 0.0 2.7 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain COG2 PF06148.11 OWF43734.1 - 0.042 13.9 3.5 0.26 11.4 0.1 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PCRF PF03462.18 OWF43734.1 - 0.054 13.4 2.1 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 PCRF domain HTH_43 PF09904.9 OWF43734.1 - 0.088 12.8 0.1 0.42 10.6 0.1 2.1 1 1 1 2 2 2 0 Winged helix-turn helix MscS_porin PF12795.7 OWF43734.1 - 0.14 11.7 10.7 0.12 11.9 6.5 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 OWF43734.1 - 0.16 12.0 4.0 1.5 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 OWF43734.1 - 0.19 11.6 4.3 0.37 10.6 0.9 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 OWF43734.1 - 0.29 11.3 5.0 3.4 7.9 0.6 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 OWF43734.1 - 0.33 11.4 5.9 0.45 10.9 0.5 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.6 OWF43734.1 - 0.34 11.3 8.8 6 7.3 1.9 3.1 3 0 0 3 3 3 0 Syntaxin-like protein TMPIT PF07851.13 OWF43734.1 - 0.38 10.0 3.8 0.59 9.3 0.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 OWF43734.1 - 0.42 10.6 6.1 0.36 10.8 1.6 2.3 2 0 0 2 2 2 0 Laminin Domain II zf-C4H2 PF10146.9 OWF43734.1 - 0.6 10.4 6.7 0.15 12.4 1.8 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein XhlA PF10779.9 OWF43734.1 - 0.95 9.7 9.8 3.3 8.0 0.2 3.9 2 2 1 3 3 3 0 Haemolysin XhlA BST2 PF16716.5 OWF43734.1 - 2.4 8.8 6.1 7.4 7.2 1.4 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF948 PF06103.11 OWF43734.1 - 3.1 8.1 5.1 2.9 8.2 0.8 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LSPR PF06049.12 OWF43734.1 - 3.6 7.8 5.1 30 5.0 0.1 3.2 3 0 0 3 3 3 0 Coagulation Factor V LSPD Repeat SlyX PF04102.12 OWF43734.1 - 6.5 7.5 7.7 8.1 7.1 1.5 2.7 2 0 0 2 2 2 0 SlyX Oxysterol_BP PF01237.18 OWF43735.1 - 2.9e-130 434.4 4.0 2.9e-130 434.4 4.0 2.2 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 OWF43735.1 - 2.5e-08 34.1 0.5 9.8e-08 32.2 0.5 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OWF43735.1 - 1.6e-06 28.5 1.2 1.6e-06 28.5 1.2 2.3 2 0 0 2 2 2 1 PH domain WW PF00397.26 OWF43736.1 - 1.3e-07 31.6 1.0 3.5e-07 30.2 1.0 1.7 1 0 0 1 1 1 1 WW domain Ras PF00071.22 OWF43737.1 - 2.3e-35 121.6 0.1 3.4e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF43737.1 - 7.3e-16 58.5 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF43737.1 - 2.8e-07 30.2 0.1 3.8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF43737.1 - 0.00047 20.2 0.0 0.0007 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF43737.1 - 0.00062 19.4 0.3 0.0019 17.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OWF43737.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 OWF43737.1 - 0.006 16.0 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit XFP_N PF09364.10 OWF43737.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 XFP N-terminal domain AAA_22 PF13401.6 OWF43737.1 - 0.037 14.3 0.2 0.16 12.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OWF43737.1 - 0.075 12.7 0.1 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF43737.1 - 0.11 12.4 0.0 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Lectin_C PF00059.21 OWF43738.1 - 6.9e-19 68.6 1.1 9.9e-19 68.1 1.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF43738.1 - 3.2e-05 23.7 1.6 4e-05 23.4 1.6 1.3 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like zf-RING_UBOX PF13445.6 OWF43740.1 - 6.9e-10 38.8 7.8 6.9e-10 38.8 7.8 3.6 3 2 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF43740.1 - 6.3e-09 35.9 9.4 6.3e-09 35.9 9.4 3.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 OWF43740.1 - 5.7e-08 32.8 10.3 5.7e-08 32.8 10.3 4.6 3 1 1 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF43740.1 - 6.2e-08 32.4 8.3 6.2e-08 32.4 8.3 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF43740.1 - 6.7e-08 32.7 9.9 6.7e-08 32.7 9.9 3.9 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF43740.1 - 2.7e-07 30.3 9.4 2.7e-07 30.3 9.4 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF43740.1 - 3.6e-06 26.7 10.5 3.6e-06 26.7 10.5 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF43740.1 - 1.2e-05 25.2 7.9 1.2e-05 25.2 7.9 3.9 2 1 1 3 3 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF43740.1 - 0.0039 17.0 11.2 0.0039 17.0 11.2 3.7 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF43740.1 - 0.0078 16.0 6.3 0.0078 16.0 6.3 4.0 3 1 1 4 4 4 1 RING/Ubox like zinc-binding domain Snapin_Pallidin PF14712.6 OWF43740.1 - 0.21 12.0 0.5 6.3 7.3 0.0 2.4 1 1 1 2 2 2 0 Snapin/Pallidin Zn_ribbon_SprT PF17283.2 OWF43740.1 - 8 6.5 12.1 2.7 8.0 4.9 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain TMC PF07810.13 OWF43741.1 - 6.8e-19 68.5 0.7 3.8e-18 66.1 0.7 2.4 1 1 0 1 1 1 1 TMC domain DUF4205 PF13898.6 OWF43742.1 - 3.1e-128 427.6 0.0 4.1e-128 427.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Caprin-1_C PF12287.8 OWF43744.1 - 0.035 14.3 3.0 0.035 14.2 3.0 1.0 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term BA14K PF07886.11 OWF43744.1 - 7.6 6.5 11.5 20 5.1 0.6 3.3 1 1 2 3 3 3 0 BA14K-like protein 7tm_2 PF00002.24 OWF43746.1 - 2.2e-11 43.5 19.7 2.2e-11 43.5 19.7 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Virul_fac_BrkB PF03631.15 OWF43746.1 - 0.0047 16.6 7.2 0.0047 16.6 7.2 2.9 2 1 1 3 3 3 1 Virulence factor BrkB Peptidase_M9_N PF08453.10 OWF43746.1 - 0.057 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Somatomedin_B PF01033.17 OWF43746.1 - 0.082 13.3 30.3 0.35 11.3 11.7 3.9 3 0 0 3 3 3 0 Somatomedin B domain Ub-RnfH PF03658.14 OWF43747.1 - 0.00015 22.1 18.0 88 3.6 0.1 8.7 1 1 2 3 3 3 1 RnfH family Ubiquitin Pkinase_Tyr PF07714.17 OWF43748.1 - 1.4e-90 303.1 0.0 1.9e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF43748.1 - 2.2e-46 158.4 0.0 3.9e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 OWF43748.1 - 2.1e-35 121.1 2.1 2.1e-12 47.4 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 OWF43748.1 - 2.5e-29 101.3 4.6 1.9e-08 34.3 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 OWF43748.1 - 2.1e-27 95.0 0.2 4.2e-09 36.4 0.0 4.7 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF43748.1 - 2.4e-20 72.7 6.5 2.6e-06 27.7 0.0 5.3 4 2 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 OWF43748.1 - 7.5e-19 67.9 14.3 4.4e-06 26.8 0.2 5.5 5 2 0 5 5 4 4 Immunoglobulin V-set domain cEGF PF12662.7 OWF43748.1 - 2e-12 46.8 13.4 6.3e-08 32.4 2.3 3.4 3 0 0 3 3 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF43748.1 - 2.5e-11 43.6 37.3 3.8e-06 27.0 9.9 4.4 4 0 0 4 4 4 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF43748.1 - 7.2e-11 42.2 27.8 2.2e-05 24.6 7.1 3.0 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site Ig_6 PF18452.1 OWF43748.1 - 1.8e-08 33.8 3.4 0.13 11.9 0.0 4.8 5 0 0 5 5 5 2 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 OWF43748.1 - 1.8e-05 24.4 0.7 0.78 9.6 0.1 4.7 4 1 0 4 4 4 1 Adenovirus E3 region protein CR1 Izumo-Ig PF16706.5 OWF43748.1 - 2.3e-05 24.4 0.9 1.3 9.1 0.0 4.0 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 OWF43748.1 - 0.00013 22.3 5.2 0.2 12.0 0.9 4.9 4 1 0 4 4 4 1 Immunoglobulin C1-set domain EphA2_TM PF14575.6 OWF43748.1 - 0.00094 20.0 0.0 0.2 12.5 0.0 3.2 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 OWF43748.1 - 0.0011 18.9 0.0 0.13 12.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family MAP17 PF15807.5 OWF43748.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Syndecan PF01034.20 OWF43748.1 - 0.51 10.3 0.0 0.51 10.3 0.0 1.9 2 0 0 2 2 1 0 Syndecan domain Cytomega_TRL10 PF06084.11 OWF43748.1 - 0.71 9.9 5.8 0.13 12.2 0.8 2.2 1 1 1 2 2 2 0 Cytomegalovirus TRL10 protein EGF PF00008.27 OWF43748.1 - 3.7 7.9 26.8 0.11 12.8 10.0 3.4 3 0 0 3 3 3 0 EGF-like domain Adeno_E3_CR2 PF02439.15 OWF43748.1 - 5.5 6.8 7.4 0.28 11.0 0.4 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Cation_ATPase_C PF00689.21 OWF43749.1 - 1.2e-42 145.7 3.2 1.2e-42 145.7 0.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OWF43749.1 - 6.6e-41 139.8 1.3 6.6e-41 139.8 1.3 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OWF43749.1 - 1.7e-24 85.7 0.0 3.8e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OWF43749.1 - 2.1e-18 67.4 0.3 6e-15 56.1 0.3 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OWF43749.1 - 4.5e-18 64.7 0.0 8.1e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OWF43749.1 - 2.6e-06 27.4 0.5 0.00063 19.6 0.4 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ig_3 PF13927.6 OWF43750.1 - 2.7e-29 101.6 0.3 5.9e-11 42.8 0.0 3.5 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 OWF43750.1 - 6.4e-26 90.3 0.2 1.6e-09 37.7 0.0 3.7 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF43750.1 - 6.2e-20 71.3 0.1 1.4e-06 28.5 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF43750.1 - 1e-15 57.8 3.3 2e-05 24.7 0.2 5.0 3 2 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.25 OWF43750.1 - 1.7e-15 56.9 0.1 3.5e-05 23.9 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 OWF43750.1 - 0.12 12.6 0.0 3.9 7.8 0.0 2.7 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 OWF43750.1 - 0.29 11.6 3.1 4.6 7.7 0.0 2.8 3 1 0 3 3 3 0 Immunoglobulin C1-set domain Phage_Gp15 PF06854.11 OWF43751.1 - 0.0051 16.8 2.2 0.019 14.9 0.2 2.3 1 1 1 2 2 2 1 Bacteriophage Gp15 protein SRP54 PF00448.22 OWF43752.1 - 7.3e-78 260.7 1.3 8.1e-78 260.6 0.1 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OWF43752.1 - 1.1e-29 103.0 2.1 1.1e-29 103.0 2.1 3.6 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 OWF43752.1 - 4.1e-20 71.8 2.7 4.1e-20 71.8 2.7 2.0 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 OWF43752.1 - 6.5e-07 29.1 1.0 1e-05 25.2 1.0 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OWF43752.1 - 1e-05 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OWF43752.1 - 2.6e-05 24.3 0.0 0.00016 21.7 0.0 2.3 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 OWF43752.1 - 0.00046 20.2 0.8 0.0068 16.4 0.2 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SRPRB PF09439.10 OWF43752.1 - 0.00076 19.0 0.5 0.77 9.2 0.0 2.6 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit DUF2209 PF09974.9 OWF43752.1 - 0.002 18.4 0.2 0.006 16.9 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA PF00004.29 OWF43752.1 - 0.0021 18.5 3.8 0.14 12.6 0.1 4.0 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OWF43752.1 - 0.0047 16.7 0.0 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OWF43752.1 - 0.0057 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_31 PF13614.6 OWF43752.1 - 0.0069 16.3 0.2 0.02 14.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 OWF43752.1 - 0.0082 16.6 0.2 0.0082 16.6 0.2 2.6 4 1 0 4 4 1 1 AAA domain G-alpha PF00503.20 OWF43752.1 - 0.011 14.9 0.2 0.091 11.9 0.0 2.2 2 1 0 2 2 2 0 G-protein alpha subunit MeaB PF03308.16 OWF43752.1 - 0.015 14.3 0.3 0.16 10.9 0.0 2.7 3 1 1 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 OWF43752.1 - 0.025 14.9 0.0 0.06 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF43752.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OWF43752.1 - 0.031 14.0 0.6 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OWF43752.1 - 0.031 14.3 1.3 0.11 12.5 0.2 2.5 2 1 0 2 2 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF43752.1 - 0.039 13.7 1.0 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 OWF43752.1 - 0.051 13.5 0.3 0.15 12.0 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 OWF43752.1 - 0.054 13.8 1.7 0.32 11.2 0.2 2.8 2 1 0 2 2 2 0 AAA domain 6PF2K PF01591.18 OWF43752.1 - 0.054 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_24 PF13479.6 OWF43752.1 - 0.065 13.0 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 OWF43752.1 - 0.066 13.0 0.6 4.2 7.1 0.1 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 OWF43752.1 - 0.091 13.0 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 OWF43752.1 - 0.13 11.4 0.1 0.13 11.4 0.1 4.2 3 2 0 4 4 4 0 Anion-transporting ATPase AAA_18 PF13238.6 OWF43752.1 - 0.15 12.6 0.1 0.6 10.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain CLTH PF10607.9 OWF43752.1 - 0.27 11.1 1.6 0.33 10.8 0.2 1.9 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain DUF3486 PF11985.8 OWF43752.1 - 3.5 8.0 5.9 3 8.2 0.0 3.6 3 2 2 5 5 5 0 Protein of unknown function (DUF3486) Paramyxo_P PF01806.17 OWF43752.1 - 7.4 5.9 5.8 12 5.2 0.2 3.4 3 2 1 4 4 4 0 Paramyxovirinae P phosphoprotein C-terminal region GAT PF03127.14 OWF43752.1 - 8.8 6.7 9.0 2.6 8.4 0.2 3.7 4 0 0 4 4 3 0 GAT domain Acyltransf_C PF16076.5 OWF43753.1 - 2.9e-11 43.3 0.5 6.7e-11 42.1 0.5 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 OWF43753.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase XPG_I PF00867.18 OWF43754.1 - 3.7e-23 81.7 0.1 1.2e-22 80.0 0.1 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OWF43754.1 - 5.1e-21 75.0 0.0 1.6e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 OWF43754.1 - 2.9e-05 23.7 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing DUF5054 PF16477.5 OWF43754.1 - 0.042 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) TPR_2 PF07719.17 OWF43754.1 - 0.11 12.6 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF43754.1 - 0.23 12.4 0.1 0.44 11.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5014 PF16406.5 OWF43756.1 - 1.6 9.0 5.7 41 4.6 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5014) zf-met2 PF12907.7 OWF43756.1 - 2.5 8.3 3.8 5.1 7.3 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding Cadherin PF00028.17 OWF43758.1 - 1.7e-94 310.5 21.3 2.8e-17 62.9 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF43758.1 - 2.7e-17 62.3 1.6 1.6e-10 40.7 0.0 6.5 7 0 0 7 7 7 2 Cadherin-like RET_CLD1 PF17756.1 OWF43758.1 - 0.00093 19.5 0.1 5.4 7.3 0.0 3.8 3 0 0 3 3 3 2 RET Cadherin like domain 1 Cadherin_3 PF16184.5 OWF43758.1 - 0.005 16.8 19.4 0.59 10.2 0.1 6.6 7 0 0 7 7 7 2 Cadherin-like SusE PF14292.6 OWF43758.1 - 0.14 12.4 1.7 1.5 9.1 0.1 3.4 2 0 0 2 2 2 0 SusE outer membrane protein HSP70 PF00012.20 OWF43759.1 - 5.6e-19 67.8 1.0 2.3e-08 32.7 0.1 4.3 3 2 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OWF43759.1 - 6.6e-05 21.9 4.5 0.18 10.6 0.0 3.3 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 OWF43759.1 - 0.0082 16.6 0.8 4.7 7.7 0.2 2.8 2 0 0 2 2 2 2 Cell division protein FtsA DUF3867 PF12983.7 OWF43759.1 - 0.16 12.0 3.3 8.5 6.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) TSP_1 PF00090.19 OWF43760.1 - 1.3e-94 310.2 165.0 5.2e-11 42.6 7.1 10.9 10 0 0 10 10 10 10 Thrombospondin type 1 domain SRCR PF00530.18 OWF43760.1 - 5.2e-49 164.9 7.1 8.4e-26 90.4 0.7 6.4 8 1 0 8 8 8 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF43760.1 - 1e-09 38.8 0.1 5.5e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 OWF43760.1 - 4.3e-05 23.6 6.8 4.3e-05 23.6 6.8 6.4 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A CHZ PF09649.10 OWF43760.1 - 0.086 12.3 16.4 55 3.3 0.0 7.3 8 0 0 8 8 8 0 Histone chaperone domain CHZ p450 PF00067.22 OWF43761.1 - 1.3e-114 383.5 0.0 1.4e-114 383.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kinesin PF00225.23 OWF43762.1 - 1.7e-114 382.2 0.1 1.7e-114 382.2 0.1 2.5 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF43762.1 - 1.7e-21 76.7 0.0 1.7e-21 76.7 0.0 2.7 3 0 0 3 3 3 1 Microtubule binding DUF3800 PF12686.7 OWF43762.1 - 2.7 8.6 11.7 1.8e+04 -3.8 11.7 5.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Laminin_G_2 PF02210.24 OWF43764.1 - 0.13 12.8 0.0 0.62 10.6 0.0 2.2 2 1 0 2 2 2 0 Laminin G domain MR_MLE_C PF13378.6 OWF43765.1 - 1.3e-44 152.4 0.0 2.2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OWF43765.1 - 1.2e-09 38.4 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE_C PF13378.6 OWF43766.1 - 5.3e-46 156.9 0.0 7.8e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OWF43766.1 - 7.7e-10 39.0 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Melibiase_2 PF16499.5 OWF43767.1 - 7.4e-141 468.3 1.1 8.9e-141 468.0 1.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 OWF43767.1 - 2.5e-09 37.2 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 OWF43767.1 - 4.5e-06 25.9 0.0 9.3e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_C PF17801.1 OWF43767.1 - 0.00023 21.2 0.0 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 OWF43767.1 - 0.0028 17.0 0.1 0.0056 16.0 0.0 1.4 2 0 0 2 2 2 1 Glycoside hydrolase 97 2Fe-2S_thioredx PF01257.19 OWF43767.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin AcrZ PF10766.9 OWF43767.1 - 0.51 9.9 2.1 1 9.0 2.1 1.5 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Tubulin PF00091.25 OWF43769.1 - 6.7e-69 232.0 0.0 1e-68 231.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF43769.1 - 5.4e-42 142.9 0.0 8e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OWF43769.1 - 4e-05 23.9 0.0 9.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OWF43769.1 - 0.02 14.1 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 OWF43769.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain FAM47 PF14642.6 OWF43770.1 - 1.8e-12 47.4 0.4 1.8e-12 47.4 0.4 1.7 2 0 0 2 2 2 1 FAM47 family Myb_DNA-bind_2 PF08914.11 OWF43771.1 - 2.1e-13 50.2 0.0 6.2e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 OWF43771.1 - 5.9e-12 45.8 1.2 5.2e-11 42.8 0.0 3.1 4 0 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain Rap1_C PF11626.8 OWF43771.1 - 1.3e-05 25.2 0.6 3.3e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Phage_int_SAM_3 PF14659.6 OWF43771.1 - 0.018 15.3 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3438 PF11920.8 OWF43771.1 - 0.027 13.7 0.3 0.055 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) DUF236 PF03057.14 OWF43772.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 DUF236 repeat PAS_3 PF08447.12 OWF43773.1 - 2e-22 79.3 0.1 1.7e-17 63.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 OWF43773.1 - 1.5e-21 76.6 0.9 1.3e-18 67.2 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 OWF43773.1 - 1.8e-09 37.6 0.3 8.4e-06 25.8 0.0 2.8 3 0 0 3 3 3 2 PAS fold HLH PF00010.26 OWF43773.1 - 8.3e-07 28.9 0.1 2.1e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 OWF43773.1 - 0.01 16.1 0.0 0.049 13.9 0.0 2.3 2 1 0 2 2 2 0 PAS domain PAS_4 PF08448.10 OWF43773.1 - 0.017 15.4 0.0 0.15 12.4 0.0 2.5 3 0 0 3 3 3 0 PAS fold SNF2_N PF00176.23 OWF43774.1 - 5.8e-52 176.5 1.1 1.6e-51 175.1 1.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain ADD_ATRX PF17981.1 OWF43774.1 - 4.6e-19 68.0 0.5 1.3e-18 66.6 0.5 1.8 1 0 0 1 1 1 1 Cysteine Rich ADD domain Helicase_C PF00271.31 OWF43774.1 - 5.7e-14 52.4 0.8 8e-13 48.7 0.8 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain PH PF00169.29 OWF43776.1 - 0.0065 17.0 0.1 0.0083 16.6 0.1 1.3 1 0 0 1 1 1 1 PH domain DUF3967 PF13152.6 OWF43776.1 - 0.8 9.5 2.5 0.84 9.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) Phage_holin_2_4 PF16082.5 OWF43777.1 - 2 8.2 4.1 7.7 6.3 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like 7TM_GPCR_Srw PF10324.9 OWF43778.1 - 3.5e-11 43.0 32.4 5.3e-11 42.4 32.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF43778.1 - 0.00016 21.1 29.6 0.00025 20.4 29.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 OWF43778.1 - 0.0055 16.4 38.2 0.013 15.1 37.8 1.7 1 1 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srw PF10324.9 OWF43779.1 - 1.3e-08 34.6 32.1 2e-08 33.9 32.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF43779.1 - 0.00032 20.1 31.1 0.00051 19.4 31.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 OWF43779.1 - 0.015 15.0 35.9 0.023 14.3 35.6 1.5 1 1 0 1 1 1 0 Srg family chemoreceptor GTP_EFTU PF00009.27 OWF43780.1 - 6.3e-32 110.7 0.0 6.3e-32 110.7 0.0 3.7 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OWF43780.1 - 2.3e-18 66.3 0.1 7e-18 64.7 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 OWF43780.1 - 6.9e-14 51.5 0.0 1.8e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 OWF43780.1 - 1.8e-13 50.7 0.6 9.8e-08 32.3 0.1 3.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF43780.1 - 2.7e-06 27.4 0.1 2.7e-06 27.4 0.1 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OWF43780.1 - 0.0014 18.8 0.0 0.0045 17.2 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OWF43780.1 - 0.15 11.9 2.0 0.72 9.7 0.4 2.6 1 1 1 2 2 2 0 RsgA GTPase Sprouty PF05210.13 OWF43781.1 - 7e-26 90.6 33.7 9.5e-26 90.2 32.9 1.5 1 1 0 1 1 1 1 Sprouty protein (Spry) Planc_extracel PF07595.12 OWF43781.1 - 0.16 11.9 0.4 0.32 10.8 0.4 1.6 1 0 0 1 1 1 0 Planctomycete extracellular DUF4573 PF15140.6 OWF43782.1 - 7.5e-18 64.9 6.3 6.9e-14 52.0 1.0 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) PheRS_DBD1 PF18552.1 OWF43782.1 - 9e-08 31.8 57.9 1.1 9.1 0.9 12.7 1 1 10 11 11 11 11 PheRS DNA binding domain 1 SLT PF01464.20 OWF43783.1 - 0.0018 17.9 0.1 0.038 13.6 0.1 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain 7tm_1 PF00001.21 OWF43784.1 - 2.5e-22 79.5 20.7 3.2e-22 79.1 20.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF43784.1 - 4.2e-07 29.6 25.7 1.9e-06 27.4 25.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 OWF43784.1 - 2.3e-05 24.3 3.1 2.3e-05 24.3 3.1 1.9 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF43784.1 - 0.0014 18.3 26.2 0.0031 17.2 26.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2633 PF11119.8 OWF43784.1 - 0.053 13.4 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Fucokinase PF07959.12 OWF43785.1 - 1.3e-114 383.4 0.4 1.5e-114 383.1 0.4 1.1 1 0 0 1 1 1 1 L-fucokinase Polysacc_deac_1 PF01522.21 OWF43786.1 - 8.2e-06 25.7 0.1 0.00011 22.1 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide deacetylase 7tm_2 PF00002.24 OWF43786.1 - 0.017 14.4 0.3 0.046 13.0 0.3 1.7 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) MerT PF02411.15 OWF43786.1 - 0.093 12.8 4.0 8.6 6.4 1.0 2.6 2 1 1 3 3 3 0 MerT mercuric transport protein adh_short PF00106.25 OWF43787.1 - 4.9e-29 101.2 0.0 4.8e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF43787.1 - 3.9e-14 52.8 0.0 1.4e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF43787.1 - 9.7e-07 28.9 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF43787.1 - 0.0062 16.0 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SDA1 PF05285.12 OWF43788.1 - 5.2e-70 236.6 50.4 1.1e-37 130.3 6.8 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 OWF43788.1 - 2.2e-21 75.9 0.5 1.1e-20 73.7 0.6 2.3 2 0 0 2 2 2 1 NUC130/3NT domain eIF3_subunit PF08597.10 OWF43788.1 - 2.5 7.9 32.1 1.2 9.0 6.4 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit MFS_1 PF07690.16 OWF43789.1 - 3.1e-13 49.4 35.5 2.2e-12 46.6 34.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OWF43789.1 - 6.7e-09 34.8 6.8 6.7e-09 34.8 6.8 2.2 2 1 1 3 3 3 1 MFS/sugar transport protein DUF412 PF04217.13 OWF43789.1 - 0.26 11.2 2.0 0.82 9.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF412 MFS_1 PF07690.16 OWF43790.1 - 1.4e-21 76.8 32.3 4.9e-21 75.1 32.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OWF43790.1 - 6.8e-06 24.9 3.0 6.8e-06 24.9 3.0 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Orf78 PF06024.12 OWF43790.1 - 0.0066 16.7 0.3 1.3 9.3 0.0 3.0 3 0 0 3 3 3 1 Orf78 (ac78) Oxidored_q2 PF00420.24 OWF43790.1 - 0.27 10.9 4.4 5.4 6.7 0.0 2.8 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MFS_1 PF07690.16 OWF43791.1 - 1.7e-13 50.3 30.1 9.5e-13 47.8 30.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Nucleos_tra2_N PF01773.20 OWF43791.1 - 0.035 14.7 2.0 1.1 9.9 2.0 2.9 1 1 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus PGM_PMM_I PF02878.16 OWF43792.1 - 4.8e-37 126.7 0.0 8.6e-37 125.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OWF43792.1 - 3.7e-21 75.7 0.0 9.5e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OWF43792.1 - 1.2e-12 48.1 0.0 1.9e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OWF43792.1 - 6.3e-07 29.5 0.0 1.8e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Galactosyl_T PF01762.21 OWF43794.1 - 1.3e-39 136.1 0.1 1.8e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Glycophorin_A PF01102.18 OWF43795.1 - 0.0051 17.0 5.4 0.0095 16.2 5.4 1.4 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 OWF43795.1 - 0.0067 16.5 11.3 0.013 15.6 11.3 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 OWF43795.1 - 0.047 13.6 8.9 0.088 12.7 8.9 1.5 1 0 0 1 1 1 0 TMEM154 protein family Mucin PF01456.17 OWF43795.1 - 0.23 11.5 33.9 0.029 14.4 29.4 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein LRR19-TM PF15176.6 OWF43795.1 - 5.4 7.1 5.8 0.93 9.5 0.1 2.5 3 1 0 3 3 3 0 Leucine-rich repeat family 19 TM domain LapA_dom PF06305.11 OWF43796.1 - 0.01 15.7 0.2 0.022 14.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SIT PF15330.6 OWF43796.1 - 0.069 13.6 0.3 3.8 8.0 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.6 OWF43796.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 OWF43797.1 - 0.027 13.9 1.5 0.064 12.7 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) PetG PF02529.15 OWF43797.1 - 0.036 13.9 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 TMEM154 PF15102.6 OWF43797.1 - 0.051 13.5 0.4 0.051 13.5 0.4 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF5349 PF17298.2 OWF43797.1 - 0.93 9.2 11.4 1.6 8.4 1.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5349) DUF229 PF02995.17 OWF43798.1 - 5.6e-114 381.5 0.2 8.8e-114 380.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF43798.1 - 1e-06 28.4 0.1 9.6e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Sulfatase Cystatin PF00031.21 OWF43798.1 - 0.16 12.2 0.7 0.38 11.1 0.7 1.6 1 0 0 1 1 1 0 Cystatin domain SIT PF15330.6 OWF43799.1 - 0.01 16.3 0.2 0.027 14.9 0.2 1.8 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Protocadherin PF08374.11 OWF43799.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Protocadherin LRR19-TM PF15176.6 OWF43799.1 - 0.013 15.4 0.1 0.049 13.6 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain PepSY_TM PF03929.16 OWF43799.1 - 0.018 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region EphA2_TM PF14575.6 OWF43799.1 - 0.023 15.6 0.2 0.081 13.8 0.2 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2681 PF10883.8 OWF43799.1 - 0.091 13.2 3.2 0.19 12.1 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Ank_2 PF12796.7 OWF43800.1 - 5.4e-46 155.1 0.2 5.3e-12 46.2 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 OWF43800.1 - 2.9e-41 138.2 5.3 2.8e-05 24.3 0.1 9.9 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 OWF43800.1 - 2.9e-37 126.6 0.5 1.4e-10 41.5 0.0 6.9 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF43800.1 - 2.3e-36 119.7 6.2 0.00068 19.9 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 OWF43800.1 - 3.4e-30 103.7 0.4 6.1e-08 32.8 0.1 8.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF43800.1 - 2e-09 37.6 0.9 4.5e-09 36.5 0.9 1.6 1 0 0 1 1 1 1 SOCS box DUF3447 PF11929.8 OWF43800.1 - 0.037 14.0 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) DUF2398 PF09661.10 OWF43800.1 - 0.1 11.9 0.1 0.31 10.2 0.0 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2398) PH PF00169.29 OWF43801.1 - 1.2e-05 25.7 0.1 1.7e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 OWF43801.1 - 0.009 16.4 0.6 0.028 14.8 0.6 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain Ribosomal_S3Ae PF01015.18 OWF43802.1 - 5.4e-85 284.1 7.2 6.2e-85 283.9 7.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 OWF43802.1 - 0.0062 16.1 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region NLRC4_HD2 PF17776.1 OWF43802.1 - 0.032 14.8 0.2 0.048 14.2 0.2 1.2 1 0 0 1 1 1 0 NLRC4 helical domain HD2 PDZ PF00595.24 OWF43803.1 - 5e-13 49.2 0.3 6.2e-13 48.9 0.3 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF43803.1 - 1e-05 25.2 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF43803.1 - 0.00087 19.6 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Carb_anhydrase PF00194.21 OWF43804.1 - 1.4e-66 224.7 0.1 1.6e-66 224.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase LIG3_BRCT PF16759.5 OWF43804.1 - 0.011 16.0 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain FMO-like PF00743.19 OWF43805.1 - 2.9e-43 148.1 0.0 6.4e-30 104.1 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF43805.1 - 2e-17 63.4 0.0 8e-15 54.9 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF43805.1 - 2.9e-12 46.4 0.0 3.8e-10 39.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OWF43805.1 - 3.4e-12 46.2 0.0 6.7e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF43805.1 - 6.7e-08 32.7 0.0 0.0071 16.3 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF43805.1 - 0.00037 20.7 0.0 0.00099 19.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_22 PF13383.6 OWF43806.1 - 3.2e-19 69.5 0.1 5.1e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MIEAP PF16026.5 OWF43807.1 - 1.6e-07 31.7 0.2 3.6e-07 30.6 0.2 1.6 1 0 0 1 1 1 1 Mitochondria-eating protein SURF6 PF04935.12 OWF43807.1 - 0.00012 22.0 0.4 0.00012 22.0 0.4 1.6 2 0 0 2 2 2 1 Surfeit locus protein 6 Snapin_Pallidin PF14712.6 OWF43807.1 - 0.0039 17.6 0.5 0.0039 17.6 0.5 2.4 2 1 0 2 2 2 1 Snapin/Pallidin Fungal_TACC PF12709.7 OWF43807.1 - 0.043 14.2 9.3 0.075 13.5 1.1 3.4 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ORC3_N PF07034.11 OWF43807.1 - 0.055 12.6 0.1 0.093 11.8 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Takusan PF04822.13 OWF43807.1 - 0.082 12.8 0.3 0.082 12.8 0.3 2.2 3 0 0 3 3 3 0 Takusan Seryl_tRNA_N PF02403.22 OWF43807.1 - 0.35 11.1 6.2 0.37 11.1 2.3 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 OWF43807.1 - 6.2 6.7 5.5 1.5 8.7 0.6 2.3 2 1 0 2 2 2 0 Septum formation initiator NHL PF01436.21 OWF43808.1 - 2.6e-14 52.4 7.7 0.00037 20.4 0.1 5.3 6 0 0 6 6 6 3 NHL repeat zf-RING_UBOX PF13445.6 OWF43808.1 - 5.2e-08 32.8 5.2 5.2e-08 32.8 5.2 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF43808.1 - 1.6e-06 27.8 10.3 1.6e-06 27.8 10.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF43808.1 - 3.8e-06 27.1 10.0 3.8e-06 27.1 10.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF43808.1 - 1.1e-05 25.3 11.0 1.1e-05 25.3 11.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF43808.1 - 0.00014 21.6 8.6 0.00014 21.6 8.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF43808.1 - 0.00033 20.7 11.6 0.00033 20.7 11.6 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF43808.1 - 0.0068 16.2 12.4 0.0068 16.2 12.4 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF43808.1 - 0.0095 15.5 0.1 0.18 11.4 0.0 2.5 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region FYVE_2 PF02318.16 OWF43808.1 - 0.016 15.4 6.5 0.071 13.3 2.5 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger ApoL PF05461.11 OWF43809.1 - 6e-14 52.1 3.6 1.5e-10 40.9 2.7 2.0 1 1 1 2 2 2 2 Apolipoprotein L DUF677 PF05055.12 OWF43809.1 - 0.00017 20.6 1.9 0.00031 19.8 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF1205 PF06722.12 OWF43809.1 - 0.074 13.2 0.1 0.71 10.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1205) LPD11 PF18824.1 OWF43809.1 - 0.08 13.0 1.1 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 CPG4 PF15481.6 OWF43811.1 - 2 9.1 6.5 2 9.1 3.9 2.1 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 CUB PF00431.20 OWF43812.1 - 2.5e-22 79.3 1.0 4e-22 78.6 1.0 1.3 1 0 0 1 1 1 1 CUB domain Shisa PF13908.6 OWF43812.1 - 8.7e-05 22.8 0.5 8.7e-05 22.8 0.5 1.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator FAM163 PF15069.6 OWF43812.1 - 0.0021 18.5 0.1 0.01 16.3 0.0 2.0 2 0 0 2 2 2 1 FAM163 family Herpes_gE PF02480.16 OWF43812.1 - 0.0077 15.0 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 OWF43812.1 - 0.008 17.0 0.0 0.03 15.2 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Alpha_GJ PF03229.13 OWF43812.1 - 0.02 15.4 1.7 0.033 14.7 1.7 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J LST1 PF05083.13 OWF43812.1 - 0.12 12.6 2.1 0.22 11.8 2.1 1.4 1 0 0 1 1 1 0 LST-1 protein Comm PF15957.5 OWF43812.1 - 0.19 12.1 1.3 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Commissureless Prominin PF05478.11 OWF43812.1 - 0.64 7.9 7.8 0.93 7.4 7.8 1.1 1 0 0 1 1 1 0 Prominin CUB PF00431.20 OWF43813.1 - 1.9e-16 60.4 0.2 2.8e-16 59.8 0.2 1.3 1 0 0 1 1 1 1 CUB domain ERGIC_N PF13850.6 OWF43813.1 - 0.051 13.9 0.4 7.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Shisa PF13908.6 OWF43813.1 - 0.056 13.7 1.0 0.08 13.2 0.5 1.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator zf-LITAF-like PF10601.9 OWF43813.1 - 0.43 10.9 4.0 2.5 8.4 1.4 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain CUB PF00431.20 OWF43814.1 - 2.5e-11 43.9 0.1 7.5e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 CUB domain RCR PF12273.8 OWF43814.1 - 0.0035 18.0 0.2 0.0052 17.4 0.2 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red MCM_OB PF17207.3 OWF43814.1 - 0.024 14.5 0.4 0.044 13.6 0.4 1.4 1 1 0 1 1 1 0 MCM OB domain Shisa PF13908.6 OWF43814.1 - 0.027 14.7 0.2 0.036 14.3 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PAG PF15347.6 OWF43814.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched CUB PF00431.20 OWF43815.1 - 1.8e-19 70.1 3.1 2.4e-19 69.7 1.5 1.9 2 0 0 2 2 2 1 CUB domain MLANA PF14991.6 OWF43815.1 - 0.00021 21.5 0.1 0.00089 19.5 0.0 2.0 2 0 0 2 2 2 1 Protein melan-A LRR19-TM PF15176.6 OWF43815.1 - 0.021 14.8 0.1 0.087 12.8 0.1 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EptA_B_N PF08019.12 OWF43815.1 - 0.12 12.3 0.5 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB EphA2_TM PF14575.6 OWF43815.1 - 0.2 12.6 0.5 2.9 8.9 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 OWF43815.1 - 1.5 9.5 10.6 3.5 8.3 3.7 3.7 3 1 0 3 3 3 0 WW domain-binding protein 1 zf-H2C2_2 PF13465.6 OWF43816.1 - 1.5e-122 395.0 129.9 2.7e-09 37.0 0.8 20.0 20 0 0 20 20 20 18 Zinc-finger double domain zf-C2H2 PF00096.26 OWF43816.1 - 2.1e-84 273.5 117.4 1.1e-05 25.6 0.3 18.2 18 0 0 18 18 18 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43816.1 - 1.4e-71 230.9 113.6 0.0001 22.8 0.1 18.2 18 0 0 18 18 18 18 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43816.1 - 2.3e-36 123.4 51.9 0.034 14.4 0.1 18.5 17 1 1 18 18 18 11 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OWF43816.1 - 7.5e-26 89.6 77.7 0.0036 17.0 0.2 17.6 18 0 0 18 18 18 10 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OWF43816.1 - 9.6e-19 66.8 84.8 0.014 15.3 0.1 17.2 18 0 0 18 18 18 10 zinc-finger of a C2HC-type zf-met PF12874.7 OWF43816.1 - 2e-18 66.1 77.0 0.099 13.1 0.1 17.5 18 0 0 18 18 17 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF43816.1 - 4e-17 61.8 126.5 0.0035 17.3 0.1 19.0 19 1 0 19 19 18 9 C2H2-type zinc finger BolA PF01722.18 OWF43816.1 - 2.2e-11 43.9 26.8 0.66 10.3 1.6 10.0 6 4 3 10 10 10 6 BolA-like protein zf-C2H2_8 PF15909.5 OWF43816.1 - 7.1e-09 35.9 49.9 0.026 14.8 1.5 8.7 2 2 7 9 9 9 6 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 OWF43816.1 - 1.2e-08 35.6 47.8 2.2 9.1 1.0 9.1 7 2 2 9 9 9 6 zinc-ribbon family FYVE PF01363.21 OWF43816.1 - 3.5e-07 30.3 80.1 0.11 12.7 6.1 11.3 2 2 7 9 9 8 5 FYVE zinc finger zf_UBZ PF18439.1 OWF43816.1 - 0.00029 20.4 70.3 0.72 9.5 0.1 16.8 18 0 0 18 18 18 3 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 OWF43816.1 - 0.0018 18.6 85.4 8.7 6.7 11.9 15.1 2 2 7 10 10 10 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 OWF43816.1 - 0.014 15.4 38.0 8.5 6.5 1.0 10.2 8 3 0 8 8 8 0 Adenylate kinase, active site lid Zf_RING PF16744.5 OWF43816.1 - 0.028 14.5 56.0 0.92 9.7 0.7 13.0 3 3 11 14 14 14 0 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 OWF43816.1 - 0.03 14.4 81.4 1.4 9.1 2.3 12.5 5 3 9 14 14 14 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 OWF43816.1 - 0.037 14.7 59.9 0.24 12.1 9.5 11.6 3 3 4 8 8 8 0 Zinc finger C2H2-type, 3 repeats Ta0938 PF11494.8 OWF43816.1 - 0.26 11.6 41.6 0.94 9.8 0.5 9.9 3 3 9 12 12 12 0 Ta0938 Baculo_IE-1 PF05290.11 OWF43816.1 - 0.39 10.7 26.9 3.6 7.5 0.7 8.3 2 2 4 7 7 7 0 Baculovirus immediate-early protein (IE-0) GAGA PF09237.11 OWF43816.1 - 0.43 10.4 0.0 0.43 10.4 0.0 10.7 5 3 10 15 15 15 0 GAGA factor Scramblase PF03803.15 OWF43816.1 - 1.4 8.1 8.0 6.9 5.9 0.1 3.7 3 1 0 3 3 3 0 Scramblase HSP90 PF00183.18 OWF43817.1 - 2.5e-230 765.8 33.1 3.2e-230 765.4 33.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OWF43817.1 - 5.4e-15 55.9 0.1 1.6e-14 54.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OWF43817.1 - 4.8e-10 39.4 0.2 1.3e-09 38.0 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Astro_capsid_p PF12226.8 OWF43817.1 - 0.59 9.2 11.3 1.5 7.9 11.3 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_polI_A34 PF08208.11 OWF43817.1 - 2.2 8.4 23.0 5.7 7.0 23.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 OWF43817.1 - 2.6 6.2 17.9 4.5 5.4 17.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Cornifin PF02389.15 OWF43818.1 - 1.3e-20 74.0 45.1 3.9e-10 40.0 12.5 2.8 1 1 2 3 3 3 3 Cornifin (SPRR) family DUF4033 PF13225.6 OWF43818.1 - 2.3 8.3 23.7 13 5.9 0.1 5.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4033) YIF1 PF03878.15 OWF43819.1 - 4.6e-89 298.0 7.0 6.4e-89 297.6 7.0 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 OWF43819.1 - 2e-09 37.4 8.3 2e-09 37.4 8.3 1.7 2 0 0 2 2 2 1 Yip1 domain ApoA-II PF04711.13 OWF43819.1 - 0.17 12.0 0.2 0.33 11.1 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) Alpha-amylase PF00128.24 OWF43821.1 - 3.2e-67 227.5 0.3 6.1e-67 226.6 0.3 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 OWF43821.1 - 9.9e-31 105.1 0.1 1.8e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Ubiquitin_3 PF14836.6 OWF43821.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TPR_1 PF00515.28 OWF43823.1 - 1.7e-50 166.9 32.6 1.7e-06 27.6 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 OWF43823.1 - 1.2e-43 143.7 32.6 1.1e-05 25.2 1.2 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 OWF43823.1 - 1.6e-35 120.8 12.9 9.8e-19 67.0 2.4 3.2 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 OWF43823.1 - 6.8e-30 102.5 28.7 1e-08 34.7 0.2 7.5 6 1 1 7 7 7 5 TPR repeat TPR_16 PF13432.6 OWF43823.1 - 1.1e-23 83.6 17.8 2.7e-05 24.7 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 OWF43823.1 - 1.2e-21 75.6 19.6 0.0036 18.0 0.0 9.0 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 OWF43823.1 - 2.9e-20 70.7 26.4 0.0009 19.3 0.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 OWF43823.1 - 1.1e-19 70.5 26.4 4.8e-07 30.0 1.8 7.2 5 3 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 OWF43823.1 - 2e-18 66.6 21.1 0.00053 20.4 0.0 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 OWF43823.1 - 1.5e-17 62.2 18.0 0.0072 16.3 0.1 8.3 10 0 0 10 10 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 OWF43823.1 - 1.2e-14 53.5 15.5 0.004 17.4 0.1 8.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 OWF43823.1 - 1.3e-10 41.3 4.0 0.04 14.1 0.0 6.6 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF43823.1 - 7.9e-07 28.8 27.0 0.62 10.0 1.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF43823.1 - 8.1e-07 29.0 19.7 1.9 8.7 0.1 8.4 8 1 1 9 9 9 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OWF43823.1 - 4e-06 27.1 26.6 0.18 12.5 1.6 8.8 9 0 0 9 9 8 2 Tetratricopeptide repeat NARP1 PF12569.8 OWF43823.1 - 1.1e-05 24.6 16.1 0.011 14.7 0.2 4.4 2 2 1 3 3 3 2 NMDA receptor-regulated protein 1 NYD-SP12_N PF15015.6 OWF43823.1 - 1.9e-05 23.3 0.2 0.0056 15.1 0.0 2.6 3 0 0 3 3 3 2 Spermatogenesis-associated, N-terminal TPR_MalT PF17874.1 OWF43823.1 - 0.001 18.5 2.3 0.13 11.6 0.1 3.8 3 2 0 3 3 3 1 MalT-like TPR region ANAPC3 PF12895.7 OWF43823.1 - 0.0012 19.0 15.7 0.033 14.4 0.4 5.1 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OWF43823.1 - 0.0024 18.3 16.1 3.6 8.0 0.2 5.2 3 2 2 5 5 5 2 Bacterial transcriptional activator domain Wtap PF17098.5 OWF43823.1 - 0.0026 17.7 5.2 0.012 15.6 0.0 3.6 3 1 0 4 4 4 1 WTAP/Mum2p family TPR_3 PF07720.12 OWF43823.1 - 0.017 15.1 16.6 4.7 7.3 0.1 6.6 6 1 0 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 OWF43823.1 - 0.028 14.2 9.7 18 5.0 0.4 4.7 3 2 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_21 PF09976.9 OWF43823.1 - 0.059 13.1 25.6 2.4 7.8 0.1 5.3 4 2 0 4 4 4 0 Tetratricopeptide repeat-like domain BNIP2 PF12496.8 OWF43823.1 - 0.068 13.6 0.9 0.21 12.0 0.9 1.9 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 MIT PF04212.18 OWF43823.1 - 0.2 11.7 31.4 2.5 8.2 0.1 7.8 6 2 1 7 7 7 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 OWF43823.1 - 0.47 10.9 12.2 27 5.2 0.1 5.1 3 2 1 5 5 5 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 OWF43823.1 - 0.54 10.6 14.0 5.6 7.4 0.2 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF4749 PF15936.5 OWF43823.1 - 4.7 8.4 10.0 1 10.6 2.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4749) Forkhead PF00250.18 OWF43824.1 - 9.4e-36 122.0 0.0 2.1e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain Diphthami_syn_2 PF01902.17 OWF43825.1 - 4.9e-45 153.7 0.1 1.2e-44 152.4 0.1 1.6 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OWF43825.1 - 8.4e-24 83.9 0.0 4.8e-12 46.0 0.0 3.1 3 0 0 3 3 3 2 Endoribonuclease L-PSP Golgin_A5 PF09787.9 OWF43826.1 - 6.3e-116 387.1 27.2 6.3e-116 387.1 27.2 3.1 1 1 2 3 3 3 1 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 OWF43826.1 - 0.011 15.9 16.3 0.011 15.9 16.3 4.8 1 1 4 5 5 5 0 Tropomyosin like Dimeth_Pyl PF09505.10 OWF43826.1 - 0.11 11.0 0.3 0.17 10.4 0.3 1.3 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) MAD PF05557.13 OWF43826.1 - 3.5 5.9 72.0 0.53 8.6 18.0 4.0 1 1 3 4 4 4 0 Mitotic checkpoint protein SNAP PF14938.6 OWF43827.1 - 3e-113 378.0 20.3 3.3e-113 377.8 20.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OWF43827.1 - 1.6e-10 41.2 5.4 3.9e-05 23.9 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF43827.1 - 3.1e-06 26.8 4.4 0.35 11.0 0.1 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF43827.1 - 1e-05 25.3 12.1 0.48 10.8 0.2 5.3 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF43827.1 - 4.2e-05 23.3 9.3 1.2 9.4 0.4 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 OWF43827.1 - 9.6e-05 21.6 10.6 0.0095 15.1 2.0 2.8 1 1 2 3 3 3 2 Spatacsin C-terminus TPR_6 PF13174.6 OWF43827.1 - 0.00037 20.9 8.3 4.9 8.0 0.0 5.5 6 2 1 7 7 6 2 Tetratricopeptide repeat NSF PF02071.20 OWF43827.1 - 0.00041 20.5 32.1 1.5 9.9 0.2 9.2 10 0 0 10 10 8 3 Aromatic-di-Alanine (AdAR) repeat DUF2150 PF09920.9 OWF43827.1 - 0.00092 19.2 0.7 0.0019 18.2 0.7 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2150) TPR_14 PF13428.6 OWF43827.1 - 0.058 14.2 1.0 19 6.4 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat RPN7 PF10602.9 OWF43827.1 - 0.065 12.9 7.0 0.076 12.7 4.5 2.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 OWF43827.1 - 0.31 11.0 4.9 29 4.7 0.3 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 OWF43827.1 - 0.46 10.2 14.9 4.4 7.1 0.3 5.2 5 1 1 6 6 6 0 TPR repeat TPR_1 PF00515.28 OWF43827.1 - 0.66 9.9 16.0 2 8.4 0.4 5.5 4 1 3 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF43827.1 - 0.72 10.1 8.4 0.75 10.1 2.2 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OWF43827.1 - 2.6 8.8 9.2 33 5.2 0.2 4.4 3 2 0 5 5 4 0 Tetratricopeptide repeat Tissue_fac PF01108.17 OWF43828.1 - 1.2e-06 28.3 2.2 3.9e-06 26.7 1.1 2.4 2 0 0 2 2 2 1 Tissue factor fn3 PF00041.21 OWF43828.1 - 1.9e-06 28.1 1.1 0.022 15.1 0.2 4.4 4 0 0 4 4 4 2 Fibronectin type III domain Pkinase_Tyr PF07714.17 OWF43828.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Gram_pos_anchor PF00746.21 OWF43828.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4945 PF16303.5 OWF43828.1 - 0.062 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) CTD PF12815.7 OWF43829.1 - 2.7e-09 37.5 12.0 0.073 13.6 2.6 4.7 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Prosystemin PF07376.11 OWF43829.1 - 5.8e-07 29.2 26.4 0.27 10.7 26.3 6.5 1 1 0 1 1 1 1 Prosystemin PPP1R35_C PF15503.6 OWF43829.1 - 2.2 8.1 15.0 8.4 6.2 3.7 2.6 1 1 1 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Pkinase_Tyr PF07714.17 OWF43830.1 - 5.1e-56 189.8 0.0 1.2e-55 188.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OWF43830.1 - 4.5e-19 68.8 0.0 9.3e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF43830.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HTH_OrfB_IS605 PF12323.8 OWF43830.1 - 0.26 10.8 0.5 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain GcrA PF07750.11 OWF43830.1 - 0.32 11.4 1.4 0.59 10.5 1.4 1.3 1 0 0 1 1 1 0 GcrA cell cycle regulator TGFb_propeptide PF00688.18 OWF43831.1 - 1.6e-41 142.7 0.4 2.5e-41 142.1 0.4 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 OWF43831.1 - 2.7e-34 118.3 0.3 5.8e-34 117.2 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Conotoxin PF02950.17 OWF43831.1 - 0.097 13.7 5.3 10 7.2 0.2 3.2 3 0 0 3 3 3 0 Conotoxin WD40 PF00400.32 OWF43832.1 - 1.6e-33 114.2 12.3 7.9e-05 23.4 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 OWF43832.1 - 4.7e-08 32.7 4.5 1e-07 31.7 2.7 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OWF43832.1 - 2.4e-07 30.5 2.1 7.1e-07 29.0 2.1 1.9 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 OWF43832.1 - 1.1e-05 25.0 0.0 0.0005 19.5 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain DUF4508 PF14969.6 OWF43832.1 - 0.00022 21.4 1.1 0.82 10.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) ANAPC4_WD40 PF12894.7 OWF43832.1 - 0.0019 18.5 0.1 0.57 10.5 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain STE PF02200.16 OWF43832.1 - 0.14 12.6 0.3 8.7 6.8 0.1 3.4 1 1 2 3 3 3 0 STE like transcription factor CDKN3 PF05706.12 OWF43833.1 - 9.2e-51 171.8 0.1 1.1e-50 171.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 OWF43833.1 - 2.4e-08 33.8 0.0 4.1e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OWF43833.1 - 3.9e-07 30.0 0.0 4.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 OWF43833.1 - 0.054 12.4 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 OWF43833.1 - 0.062 13.4 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF43833.1 - 0.17 11.8 0.3 0.68 9.9 0.1 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family PET117 PF15786.5 OWF43834.1 - 2.4e-06 27.7 0.1 3.1e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Oleosin PF01277.17 OWF43834.1 - 0.011 15.5 0.3 0.015 15.0 0.1 1.4 2 0 0 2 2 2 0 Oleosin CHASE4 PF05228.13 OWF43834.1 - 0.072 13.3 0.8 5.4 7.2 0.2 2.0 1 1 1 2 2 2 0 CHASE4 domain Spectrin PF00435.21 OWF43835.1 - 1.8e-63 211.6 23.3 1.4e-21 77.0 4.5 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 OWF43835.1 - 1.2e-53 179.9 0.2 1.7e-27 95.7 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OWF43835.1 - 1.2e-26 92.6 0.0 7.2e-26 90.1 0.0 2.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OWF43835.1 - 3.1e-08 33.3 0.0 2.5e-07 30.4 0.1 2.4 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.32 OWF43835.1 - 1.4e-06 27.4 0.1 0.0079 15.7 0.0 3.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF43835.1 - 0.00026 20.7 0.2 0.01 15.7 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OWF43835.1 - 0.00043 20.7 1.6 0.0011 19.3 0.6 2.4 2 0 0 2 2 2 1 EF-hand domain pair VPS11_C PF12451.8 OWF43835.1 - 3 8.2 7.3 13 6.1 0.3 3.1 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal BLOC1_2 PF10046.9 OWF43835.1 - 3.1 8.2 12.2 7.1 7.0 0.3 4.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uds1 PF15456.6 OWF43835.1 - 4.2 7.5 10.6 1.7 8.8 0.5 3.4 3 1 0 3 3 3 0 Up-regulated During Septation DUF4764 PF15961.5 OWF43836.1 - 8.6e-57 193.4 37.2 1.2e-29 103.7 7.3 3.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4764) SpaA PF17802.1 OWF43836.1 - 0.088 13.1 1.7 0.2 12.0 0.0 2.5 2 1 0 2 2 2 0 Prealbumin-like fold domain Peptidase_C14 PF00656.22 OWF43837.1 - 4e-25 89.2 0.0 5.7e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain QueH PF02677.14 OWF43837.1 - 0.00086 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH Peptidase_C14 PF00656.22 OWF43838.1 - 4.5e-26 92.3 0.0 1.6e-25 90.5 0.0 1.9 2 1 0 2 2 2 1 Caspase domain Macscav_rec PF03523.13 OWF43839.1 - 0.0041 17.0 33.7 23 5.0 0.3 9.0 9 0 0 9 9 9 1 Macrophage scavenger receptor Tenui_N PF05733.11 OWF43839.1 - 0.084 12.4 18.4 12 5.3 0.5 5.2 1 1 5 6 6 6 0 Tenuivirus/Phlebovirus nucleocapsid protein DUF4195 PF13836.6 OWF43839.1 - 1.7 8.7 27.1 15 5.7 0.3 4.9 1 1 2 4 4 4 0 Domain of unknown function (DUF4195) SecIII_SopE_N PF05364.14 OWF43839.1 - 2.6 8.2 38.0 46 4.2 0.2 8.4 1 1 8 9 9 9 0 Salmonella type III secretion SopE effector N-terminus A2M_recep PF07677.14 OWF43839.1 - 4.9 7.9 38.1 11 6.7 1.1 6.9 1 1 7 8 8 8 0 A-macroglobulin receptor binding domain HLH PF00010.26 OWF43840.1 - 1.9e-15 56.6 0.1 4.1e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSNAXIP1_N PF15739.5 OWF43841.1 - 1.3e-15 57.7 2.8 3.2e-15 56.5 1.1 2.5 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Clathrin_H_link PF13838.6 OWF43841.1 - 4.5e-15 55.3 0.0 1.6e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 Clathrin-H-link DUF1700 PF08006.11 OWF43841.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Host_attach PF10116.9 OWF43841.1 - 0.28 11.7 3.2 0.14 12.7 0.4 1.9 2 0 0 2 2 2 0 Protein required for attachment to host cells GAS PF13851.6 OWF43841.1 - 2 7.7 16.2 0.014 14.7 6.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 OWF43841.1 - 3.4 8.0 10.8 0.099 12.9 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) AAA PF00004.29 OWF43842.1 - 7.5e-44 149.4 0.0 1.8e-43 148.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF43842.1 - 3.6e-10 39.5 0.1 9.5e-10 38.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OWF43842.1 - 3.9e-10 39.5 0.1 2e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OWF43842.1 - 1.5e-08 35.0 0.0 3.5e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OWF43842.1 - 7.4e-08 32.5 0.1 2.4e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF43842.1 - 1.7e-06 28.5 0.1 0.00079 19.9 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OWF43842.1 - 5.9e-05 22.4 0.3 0.00048 19.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OWF43842.1 - 7.2e-05 22.6 0.0 0.00025 20.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OWF43842.1 - 0.00026 21.3 0.6 0.053 13.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 OWF43842.1 - 0.0003 21.2 0.0 0.0007 20.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 OWF43842.1 - 0.00036 20.6 0.2 0.0045 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OWF43842.1 - 0.00062 19.2 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OWF43842.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF43842.1 - 0.0017 18.6 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OWF43842.1 - 0.0024 18.4 0.0 0.011 16.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OWF43842.1 - 0.0029 17.4 0.0 0.0082 15.9 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 OWF43842.1 - 0.0032 17.4 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 NTPase TsaE PF02367.17 OWF43842.1 - 0.004 17.2 0.0 0.055 13.5 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OWF43842.1 - 0.0049 16.8 0.2 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.13 OWF43842.1 - 0.0053 16.0 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 OWF43842.1 - 0.01 15.6 0.5 0.6 9.8 0.0 2.9 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.11 OWF43842.1 - 0.011 15.6 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3450 PF11932.8 OWF43842.1 - 0.019 14.3 3.3 0.031 13.6 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_7 PF12775.7 OWF43842.1 - 0.032 13.7 0.1 0.25 10.9 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OWF43842.1 - 0.047 13.6 2.0 0.17 11.8 0.0 2.5 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OWF43842.1 - 0.048 13.4 0.1 0.13 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OWF43842.1 - 0.055 12.9 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 OWF43842.1 - 0.057 12.7 0.9 0.86 8.9 0.0 2.7 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 OWF43842.1 - 0.075 12.2 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 OWF43842.1 - 0.08 12.5 2.8 0.11 12.0 0.1 2.3 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 OWF43842.1 - 0.08 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 OWF43842.1 - 0.081 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 OWF43842.1 - 0.1 13.0 0.2 0.33 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 OWF43842.1 - 0.11 13.0 0.1 0.38 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 OWF43842.1 - 0.15 11.8 0.1 0.34 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain TIR_2 PF13676.6 OWF43843.1 - 9.1e-32 110.1 0.1 1.2e-14 54.9 0.0 3.4 3 0 0 3 3 3 3 TIR domain TIR PF01582.20 OWF43843.1 - 5.4e-17 62.1 0.6 3.5e-06 26.9 0.0 3.4 3 0 0 3 3 3 3 TIR domain TIR_3 PF18567.1 OWF43843.1 - 0.1 12.6 5.7 10 6.1 0.0 3.4 3 0 0 3 3 3 0 Toll/interleukin-1 receptor domain BILBO1_N PF18281.1 OWF43843.1 - 0.17 12.3 0.5 0.45 11.0 0.5 1.7 1 0 0 1 1 1 0 BILBO1 N-terminal domain cNMP_binding PF00027.29 OWF43844.1 - 3e-46 155.4 1.4 1.6e-16 60.1 0.1 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 OWF43844.1 - 5.8e-21 75.6 0.0 1.2e-20 74.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C4 PF00105.18 OWF43845.1 - 1.2e-39 134.6 45.4 6.2e-22 77.8 17.8 2.7 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF43845.1 - 1.4e-09 37.8 3.8 3.7e-09 36.5 3.8 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Fib_alpha PF08702.10 OWF43846.1 - 0.0099 16.1 8.1 0.0099 16.1 8.1 4.4 3 2 2 5 5 5 1 Fibrinogen alpha/beta chain family M_domain PF12938.7 OWF43846.1 - 5.9 6.6 8.5 14 5.4 1.3 3.0 3 0 0 3 3 3 0 M domain of GW182 DUF4726 PF15855.5 OWF43846.1 - 6.1 7.1 5.6 14 6.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Rod_C PF10493.9 OWF43847.1 - 7.1e-113 377.9 18.6 7.1e-113 377.9 18.6 1.8 2 0 0 2 2 2 1 Rough deal protein C-terminal region ANAPC4_WD40 PF12894.7 OWF43847.1 - 0.0011 19.3 0.0 0.0043 17.3 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain SARAF PF06682.12 OWF43848.1 - 0.027 14.1 7.4 0.04 13.6 7.4 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PH PF00169.29 OWF43848.1 - 0.058 13.9 0.3 0.43 11.1 0.3 2.1 1 1 0 1 1 1 0 PH domain DUF3081 PF11280.8 OWF43848.1 - 0.84 9.5 2.6 3.1 7.7 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3081) WD40 PF00400.32 OWF43849.1 - 3e-39 132.3 20.9 5.8e-07 30.1 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 OWF43849.1 - 4.8e-24 83.9 1.0 9.4e-24 83.0 1.0 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 OWF43849.1 - 1.7e-09 37.8 2.0 0.039 14.3 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 OWF43849.1 - 2.1e-09 37.1 0.1 4.5e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 OWF43849.1 - 1.4e-06 27.3 6.6 0.15 10.6 0.1 4.9 2 2 1 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF43849.1 - 2.5e-06 27.0 0.4 0.021 14.1 0.3 2.6 1 1 0 2 2 2 2 WD40-like domain F-box PF00646.33 OWF43849.1 - 3.9e-06 26.6 0.1 1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 OWF43849.1 - 0.0059 16.2 0.5 0.019 14.5 0.5 1.9 1 1 0 1 1 1 1 F-box eIF2A PF08662.11 OWF43849.1 - 0.027 14.4 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 OWF43849.1 - 0.051 12.3 1.1 11 4.7 0.1 3.6 1 1 2 3 3 3 0 Nup133 N terminal like DUF5046 PF16465.5 OWF43849.1 - 0.16 11.4 0.0 16 4.8 0.0 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF5046) Homeodomain PF00046.29 OWF43850.1 - 1.8e-21 75.8 2.7 3e-21 75.0 2.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF43850.1 - 0.012 15.5 0.6 0.031 14.2 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain AhpC-TSA PF00578.21 OWF43851.1 - 5.5e-40 136.1 0.0 8e-40 135.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OWF43851.1 - 2.5e-17 62.9 0.0 3.5e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OWF43851.1 - 1.2e-13 50.6 0.1 2e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 OWF43851.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC Peptidase_S31 PF05578.12 OWF43852.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 Prominin PF05478.11 OWF43854.1 - 6.6e-149 497.3 9.1 8.3e-149 497.0 9.1 1.0 1 0 0 1 1 1 1 Prominin Fib_alpha PF08702.10 OWF43854.1 - 0.003 17.7 8.6 0.005 17.0 0.3 3.7 4 0 0 4 4 4 1 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OWF43854.1 - 0.0056 16.7 41.6 0.38 10.8 2.1 4.6 3 2 1 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OWF43854.1 - 0.015 15.2 1.5 0.47 10.3 0.0 3.2 5 0 0 5 5 5 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 OWF43854.1 - 0.24 11.4 5.4 5.4 7.1 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF3829 PF12889.7 OWF43854.1 - 0.85 9.0 9.7 1.1 8.7 0.6 3.7 2 2 1 4 4 4 0 Protein of unknown function (DUF3829) FlaC_arch PF05377.11 OWF43854.1 - 2.2 8.7 6.4 38 4.8 0.4 4.6 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) LPP PF04728.13 OWF43854.1 - 3.7 8.0 5.8 33 5.0 0.7 3.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF3011 PF11218.8 OWF43855.1 - 0.089 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) Acyltransferase PF01553.21 OWF43856.1 - 1.9e-21 76.1 0.1 3e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase TUDOR PF00567.24 OWF43857.1 - 5e-18 65.3 0.2 2.9e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Tudor domain Peptidase_M16_M PF16187.5 OWF43858.1 - 3.8e-98 328.2 2.0 3.8e-98 328.2 2.0 1.8 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OWF43858.1 - 2.7e-39 134.5 0.0 1.9e-38 131.8 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OWF43858.1 - 7.5e-35 120.6 0.0 4.6e-21 75.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Phosducin PF02114.16 OWF43859.1 - 0.67 8.9 5.7 0.16 10.9 0.3 2.0 2 0 0 2 2 2 0 Phosducin Sulfotransfer_1 PF00685.27 OWF43860.1 - 2.3e-16 60.1 0.0 5e-16 59.0 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF43860.1 - 3.3e-11 44.0 0.0 8.6e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Macro PF01661.21 OWF43861.1 - 6.4e-57 190.7 3.5 1.4e-28 99.3 0.7 3.8 3 0 0 3 3 3 3 Macro domain DTC PF18102.1 OWF43861.1 - 5.7e-54 181.8 0.2 1.3e-53 180.7 0.2 1.7 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_2 PF13639.6 OWF43861.1 - 2e-07 31.2 8.7 3.8e-07 30.3 5.4 2.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OWF43861.1 - 4.1e-07 29.6 10.0 4.2e-07 29.6 3.0 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OWF43861.1 - 5e-05 23.5 3.1 5e-05 23.5 3.1 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OWF43861.1 - 0.00012 21.9 6.8 0.00012 21.9 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) KH_1 PF00013.29 OWF43861.1 - 0.00056 19.7 3.7 1.3 8.9 0.2 3.8 3 0 0 3 3 3 2 KH domain zf-RING_5 PF14634.6 OWF43861.1 - 0.011 15.6 9.2 0.0096 15.9 4.9 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OWF43861.1 - 0.028 14.0 4.9 0.072 12.7 1.8 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 OWF43861.1 - 0.038 14.1 0.6 0.15 12.2 0.6 2.1 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.6 OWF43861.1 - 0.16 11.9 2.4 0.38 10.6 2.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 OWF43861.1 - 0.97 9.6 2.6 2.7 8.2 2.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 OWF43861.1 - 1.2 9.2 8.2 0.81 9.8 5.1 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 OWF43861.1 - 2.6 8.4 5.1 6.8 7.1 5.1 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 OWF43861.1 - 3.7 7.7 9.3 0.86 9.7 5.0 2.3 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4 PF00097.25 OWF43861.1 - 4.3 7.3 16.3 0.027 14.3 6.9 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rhodanese PF00581.20 OWF43862.1 - 8.2e-12 45.6 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain APH PF01636.23 OWF43863.1 - 1.2e-14 54.8 0.0 1.7e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OWF43863.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Xan_ur_permease PF00860.20 OWF43864.1 - 1.6e-75 254.3 29.4 2.7e-75 253.5 29.4 1.4 1 1 0 1 1 1 1 Permease family HRXXH PF13933.6 OWF43865.1 - 0.081 12.5 1.2 0.21 11.1 1.2 1.6 1 0 0 1 1 1 0 Putative peptidase family Bcl-2_3 PF15286.6 OWF43865.1 - 0.17 12.6 0.5 1.2 9.8 0.1 2.3 2 0 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like EVC2_like PF12297.8 OWF43866.1 - 7.9e-58 196.2 28.5 7.9e-58 196.2 28.5 4.4 1 1 3 4 4 4 2 Ellis van Creveld protein 2 like protein ParcG PF10274.9 OWF43867.1 - 1e-44 152.9 0.0 1.3e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein HLH PF00010.26 OWF43867.1 - 0.13 12.2 0.3 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Neuralized PF07177.12 OWF43868.1 - 4e-90 299.5 0.0 3e-46 157.1 0.0 2.2 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 OWF43868.1 - 5e-14 51.9 10.9 9.6e-14 51.0 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF43868.1 - 1.1e-05 25.1 8.4 1.1e-05 25.1 8.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF43868.1 - 4e-05 23.9 9.8 0.00012 22.4 9.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF43868.1 - 0.013 15.3 10.8 0.031 14.1 10.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OWF43868.1 - 0.39 10.6 8.7 1.2 9.0 8.7 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OWF43868.1 - 0.45 10.5 11.7 1.3 9.0 11.7 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF43868.1 - 4.8 7.3 9.3 10 6.3 3.3 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Trypsin PF00089.26 OWF43869.1 - 9.7e-49 166.1 0.0 3.3e-48 164.4 0.0 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF43869.1 - 1e-05 26.5 0.0 2.8e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Glyco_transf_10 PF00852.19 OWF43870.1 - 8e-20 71.3 0.3 8.7e-20 71.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Y_phosphatase PF00102.27 OWF43871.1 - 2.3e-109 364.5 2.0 3.3e-71 239.6 0.2 2.5 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF43871.1 - 8.6e-06 25.6 0.0 0.005 16.7 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF43871.1 - 0.00028 21.0 0.0 0.00093 19.3 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate EphA2_TM PF14575.6 OWF43871.1 - 0.002 19.0 0.0 0.006 17.4 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Y_phosphatase3 PF13350.6 OWF43871.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Adeno_E3_CR2 PF02439.15 OWF43871.1 - 0.022 14.5 0.1 0.022 14.5 0.1 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 OWF43871.1 - 0.064 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Y_phosphatase PF00102.27 OWF43872.1 - 5.7e-108 359.9 6.2 1.8e-70 237.2 0.1 3.3 3 1 0 3 3 3 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 OWF43872.1 - 6.5e-10 39.2 3.5 1.3e-09 38.3 3.5 1.4 1 0 0 1 1 1 1 F5/8 type C domain DSPc PF00782.20 OWF43872.1 - 3.4e-05 23.7 0.1 0.0071 16.2 0.0 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF43872.1 - 0.002 18.3 0.0 0.012 15.7 0.0 2.4 3 0 0 3 3 3 1 Inositol hexakisphosphate EphA2_TM PF14575.6 OWF43872.1 - 0.019 15.8 0.0 0.11 13.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Y_phosphatase3 PF13350.6 OWF43872.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Podoplanin PF05808.11 OWF43872.1 - 0.24 11.5 2.7 0.54 10.4 2.7 1.5 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 OWF43872.1 - 9.5 5.7 7.6 0.34 10.3 0.2 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain MAM PF00629.23 OWF43873.1 - 2.9e-25 89.0 0.1 4.1e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu SusD_RagB PF07980.11 OWF43873.1 - 0.077 12.6 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 SusD family CoA_trans PF01144.23 OWF43874.1 - 2.7e-120 399.6 3.6 5.6e-76 254.7 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 OWF43874.1 - 7.3e-06 26.0 0.1 1.3e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain FERM_C PF09380.10 OWF43875.1 - 1.6e-25 89.3 0.3 3.9e-25 88.0 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 OWF43875.1 - 4.4e-17 62.6 0.1 1e-16 61.4 0.1 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 OWF43875.1 - 3.6e-16 58.9 0.4 1.6e-15 56.7 0.2 2.2 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 OWF43875.1 - 1.5e-12 47.4 1.5 8.7e-12 44.9 1.5 2.3 1 0 0 1 1 1 1 FERM adjacent (FA) DUF4832 PF16116.5 OWF43876.1 - 3.7e-46 157.7 0.1 5.8e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) DUF4874 PF16173.5 OWF43876.1 - 2.5e-42 144.2 0.0 4e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) Galactosyl_T PF01762.21 OWF43877.1 - 4.6e-38 131.0 1.4 1.5e-31 109.8 0.1 2.1 2 0 0 2 2 2 2 Galactosyltransferase Gln-synt_C-ter PF18318.1 OWF43877.1 - 0.091 12.6 0.9 0.62 9.9 0.4 2.1 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain CcmB PF03379.13 OWF43878.1 - 0.084 12.4 34.7 1.8 8.0 0.6 7.1 1 1 7 8 8 8 0 CcmB protein Motilin_assoc PF04643.12 OWF43878.1 - 0.34 10.8 22.4 62 3.6 0.1 9.5 5 4 9 14 14 14 0 Motilin/ghrelin-associated peptide PAP2 PF01569.21 OWF43879.1 - 1.7e-21 76.4 1.1 1.7e-21 76.4 1.1 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OWF43879.1 - 0.0037 17.0 9.2 0.0056 16.4 5.1 2.6 2 1 0 2 2 2 1 PAP2 superfamily Polysacc_synt_C PF14667.6 OWF43879.1 - 0.0077 16.3 0.8 0.0077 16.3 0.8 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.15 OWF43879.1 - 0.032 14.7 2.1 3.4 8.2 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Colicin_V PF02674.16 OWF43879.1 - 1.7 8.6 10.7 0.66 9.9 0.4 3.1 3 0 0 3 3 3 0 Colicin V production protein PAP2_C PF14360.6 OWF43879.1 - 6 7.5 9.7 0.12 12.9 0.6 2.9 3 1 0 3 3 3 0 PAP2 superfamily C-terminal Kinesin PF00225.23 OWF43880.1 - 5.7e-96 321.3 0.9 9.1e-96 320.7 0.9 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF43880.1 - 3.3e-23 82.3 0.9 9.6e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Mvb12 PF09452.10 OWF43880.1 - 0.0016 18.8 0.4 0.0081 16.6 0.4 2.3 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 AAA_16 PF13191.6 OWF43880.1 - 0.014 15.7 0.0 0.05 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OWF43880.1 - 0.016 15.5 0.1 0.23 11.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain TolA_bind_tri PF16331.5 OWF43880.1 - 0.021 14.9 0.6 0.021 14.9 0.6 3.1 5 0 0 5 5 5 0 TolA binding protein trimerisation AAA_7 PF12775.7 OWF43880.1 - 0.049 13.2 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 OWF43880.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain VWD PF00094.25 OWF43880.1 - 0.069 13.4 1.3 1.4 9.1 0.3 2.6 2 0 0 2 2 2 0 von Willebrand factor type D domain Exonuc_VII_L PF02601.15 OWF43880.1 - 1.9 8.0 7.8 0.19 11.3 0.8 2.4 2 1 0 2 2 2 0 Exonuclease VII, large subunit E1_DerP2_DerF2 PF02221.15 OWF43881.1 - 6.1e-10 39.7 0.1 7.2e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 ML domain RRM_1 PF00076.22 OWF43882.1 - 6e-19 67.6 0.0 4.8e-09 35.9 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OWF43882.1 - 0.0081 16.2 0.0 0.76 9.9 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 Lactamase_B_6 PF16661.5 OWF43883.1 - 1.6e-10 40.7 0.9 1.8e-09 37.4 0.2 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 OWF43883.1 - 1.1e-05 25.6 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 OWF43883.1 - 2.5e-05 23.6 0.2 7.9e-05 22.0 0.2 1.8 1 1 0 1 1 1 1 Putative beta-lactamase-like family LRR_8 PF13855.6 OWF43884.1 - 4.1e-45 151.4 71.6 4.2e-11 42.4 5.9 5.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 OWF43884.1 - 3.1e-21 75.7 9.1 1.4e-13 50.9 3.7 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF43884.1 - 1.8e-17 63.1 39.1 2.5e-06 27.7 0.9 7.4 1 1 7 9 9 9 7 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 OWF43884.1 - 2.4e-17 63.1 5.6 3.8e-17 62.5 5.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ldl_recept_a PF00057.18 OWF43884.1 - 9e-11 41.8 18.2 1.6e-06 28.2 1.9 3.5 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A 7TM_GPCR_Srx PF10328.9 OWF43884.1 - 2.1e-05 24.3 10.8 4.4e-05 23.2 10.8 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LRR_1 PF00560.33 OWF43884.1 - 2.3e-05 24.3 40.0 0.71 10.6 0.1 10.0 10 1 0 10 10 8 4 Leucine Rich Repeat 7TM_GPCR_Srsx PF10320.9 OWF43884.1 - 0.00073 19.0 8.6 0.0015 18.0 8.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_9 PF14580.6 OWF43884.1 - 0.0014 18.2 9.3 0.012 15.1 2.1 3.0 1 1 2 3 3 3 2 Leucine-rich repeat Git3 PF11710.8 OWF43884.1 - 0.026 14.3 6.5 0.048 13.4 6.5 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 LRR_6 PF13516.6 OWF43884.1 - 0.043 13.9 25.5 2.7 8.3 0.1 7.9 7 0 0 7 7 7 0 Leucine Rich repeat 7TM_GPCR_Srbc PF10316.9 OWF43884.1 - 2.7 7.4 16.7 0.067 12.7 10.1 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc CXCXC PF03128.14 OWF43886.1 - 8.7 7.0 7.2 8.3 7.1 0.7 2.8 2 0 0 2 2 2 0 CXCXC repeat Fibrinogen_C PF00147.18 OWF43887.1 - 1.2e-28 100.5 7.5 1.3e-28 100.3 7.5 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HPIP_like PF18524.1 OWF43887.1 - 0.032 14.0 1.5 0.067 13.0 1.5 1.5 1 0 0 1 1 1 0 High potential iron-sulfur protein like EGF_2 PF07974.13 OWF43888.1 - 0.0019 18.5 53.4 0.0047 17.3 15.3 11.4 9 4 2 11 11 11 6 EGF-like domain EGF PF00008.27 OWF43888.1 - 0.0025 18.1 44.4 0.0063 16.8 8.1 11.6 11 3 0 11 11 11 6 EGF-like domain zf-C2H2 PF00096.26 OWF43891.1 - 7.8e-43 142.6 131.5 2.4e-06 27.7 3.1 13.6 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF43891.1 - 6e-34 115.0 115.9 2e-07 31.1 0.7 14.9 16 0 0 16 16 16 9 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF43891.1 - 8.7e-32 107.1 119.4 0.0015 19.2 2.4 13.8 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF43891.1 - 4.8e-09 36.3 99.3 0.0022 18.2 0.7 12.8 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF43891.1 - 7.9e-07 29.3 98.7 0.00029 21.1 1.4 12.6 12 0 0 12 12 12 5 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF43891.1 - 1.3e-06 28.6 62.9 0.001 19.3 10.2 7.2 4 1 4 8 8 8 4 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 OWF43891.1 - 0.00077 19.4 2.6 0.00077 19.4 2.6 13.3 13 2 0 13 13 13 8 C2H2-type zinc finger zf-C2HE PF16278.5 OWF43891.1 - 0.048 14.1 88.6 0.17 12.4 1.3 12.2 7 2 5 12 12 12 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 OWF43891.1 - 0.67 9.8 15.6 1.3 8.9 1.9 5.9 4 2 2 7 7 7 0 GAGA factor EF-hand_5 PF13202.6 OWF43892.1 - 0.0029 17.0 0.0 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 EF hand RGS PF00615.19 OWF43892.1 - 0.005 17.1 0.0 0.0066 16.7 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain EF-hand_7 PF13499.6 OWF43892.1 - 0.0096 16.4 0.1 0.014 15.8 0.1 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF43892.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OWF43892.1 - 0.04 13.8 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain 4F5 PF04419.14 OWF43893.1 - 2.3e-06 28.4 14.3 3.2e-06 27.9 14.3 1.2 1 0 0 1 1 1 1 4F5 protein family DUF629 PF04780.12 OWF43893.1 - 0.011 14.3 0.3 0.011 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-MYST PF17772.1 OWF43893.1 - 0.024 14.2 0.2 0.049 13.2 0.1 1.6 2 0 0 2 2 2 0 MYST family zinc finger domain zf-met2 PF12907.7 OWF43893.1 - 0.027 14.6 6.3 0.32 11.2 6.3 2.3 1 1 0 1 1 1 0 Zinc-binding zf-C2H2_4 PF13894.6 OWF43893.1 - 0.069 14.0 1.0 0.11 13.3 1.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2162 PF09930.9 OWF43893.1 - 0.25 10.7 0.1 0.29 10.5 0.1 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) FdhD-NarQ PF02634.15 OWF43894.1 - 0.022 14.4 0.3 0.034 13.8 0.3 1.2 1 0 0 1 1 1 0 FdhD/NarQ family PDZ_3 PF17815.1 OWF43894.1 - 0.078 12.8 0.1 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Acetyltransf_1 PF00583.25 OWF43895.1 - 5.8e-05 23.3 0.0 9.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 OWF43895.1 - 0.021 15.5 0.0 0.037 14.7 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_N PF12535.8 OWF43895.1 - 0.079 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal TUDOR PF00567.24 OWF43898.1 - 1.3e-05 25.2 34.7 4.8 7.2 1.2 8.6 1 1 8 9 9 9 3 Tudor domain Glyco_hydro_65C PF03633.15 OWF43898.1 - 0.00032 20.6 7.8 37 4.3 0.2 6.2 2 1 5 7 7 7 0 Glycosyl hydrolase family 65, C-terminal domain UvrB_inter PF17757.1 OWF43898.1 - 0.00043 20.4 0.3 33 4.8 0.0 5.4 1 1 3 4 4 4 0 UvrB interaction domain PI3K_rbd PF00794.18 OWF43898.1 - 0.00049 20.2 2.2 0.3 11.3 0.5 3.4 1 1 2 3 3 3 2 PI3-kinase family, ras-binding domain F-box-like PF12937.7 OWF43898.1 - 0.0015 18.4 29.9 4 7.4 0.1 6.8 3 1 3 8 8 8 1 F-box-like DUF3290 PF11694.8 OWF43898.1 - 0.003 17.5 17.0 5.6 6.9 1.4 5.3 1 1 6 7 7 7 3 Protein of unknown function (DUF3290) NusG_II PF07009.11 OWF43898.1 - 0.0087 16.3 2.0 1.2 9.4 0.6 2.7 1 1 2 3 3 3 3 NusG domain II Ribosomal_S19 PF00203.21 OWF43898.1 - 0.0098 15.8 1.8 18 5.3 0.1 3.8 1 1 3 4 4 4 0 Ribosomal protein S19 Me-amine-dh_L PF02975.14 OWF43898.1 - 0.035 14.6 12.6 3 8.4 0.1 4.3 1 1 2 3 3 3 0 Methylamine dehydrogenase, L chain NEAT PF05031.12 OWF43898.1 - 0.037 14.6 20.2 2.6e+02 2.3 20.2 3.5 1 1 0 1 1 1 0 Iron Transport-associated domain SPOR PF05036.13 OWF43898.1 - 0.062 13.7 33.2 21 5.6 0.4 7.6 1 1 3 4 4 3 0 Sporulation related domain GH43_C2 PF17851.1 OWF43898.1 - 0.38 10.4 8.3 19 4.9 8.3 2.5 1 1 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain TRP_N PF14558.6 OWF43898.1 - 0.5 10.7 9.9 9e+02 0.2 9.9 3.3 1 1 0 1 1 1 0 ML-like domain 7TMR-DISMED2 PF07696.11 OWF43898.1 - 2.3 8.3 24.0 68 3.5 2.0 6.3 1 1 2 3 3 3 0 7TMR-DISM extracellular 2 CBM9_2 PF16011.5 OWF43898.1 - 3.8 7.2 12.7 5.7 6.6 1.2 2.7 1 1 2 3 3 3 0 Carbohydrate-binding family 9 DUF756 PF05506.12 OWF43898.1 - 5.7 7.9 29.3 91 4.1 4.3 4.9 1 1 2 3 3 2 0 Domain of unknown function (DUF756) DUF4115 PF13464.6 OWF43898.1 - 6.7 7.0 31.9 33 4.8 1.4 6.3 1 1 7 8 8 8 0 Domain of unknown function (DUF4115) PT PF04886.12 OWF43899.1 - 0.0096 15.4 25.0 1.4 8.5 0.8 5.7 2 1 1 3 3 3 3 PT repeat SH3_9 PF14604.6 OWF43900.1 - 4.2e-69 228.2 4.4 1.4e-13 50.4 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 OWF43900.1 - 1.4e-61 203.9 12.8 3.1e-15 55.5 0.0 5.7 5 0 0 5 5 5 5 SH3 domain PH_13 PF16652.5 OWF43900.1 - 2.3e-61 206.2 1.1 2.3e-61 206.2 1.1 3.3 3 1 0 3 3 2 1 Pleckstrin homology domain SH3_2 PF07653.17 OWF43900.1 - 6.4e-49 163.5 5.4 1.7e-09 37.2 0.0 5.9 6 0 0 6 6 6 5 Variant SH3 domain RhoGEF PF00621.20 OWF43900.1 - 4.2e-39 134.7 0.1 4.2e-39 134.7 0.1 2.9 3 0 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.7 OWF43900.1 - 1.2e-28 99.1 0.1 1.7e-12 47.2 0.0 3.6 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 OWF43900.1 - 5.5e-25 87.6 0.0 1.8e-24 86.0 0.0 2.0 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 OWF43900.1 - 3.4e-09 35.6 0.3 0.0052 16.2 0.1 3.4 3 0 0 3 3 3 2 EF hand PH_16 PF17838.1 OWF43900.1 - 8.7e-07 28.8 1.2 1.2e-06 28.4 0.0 1.8 2 0 0 2 2 1 1 PH domain EF-hand_6 PF13405.6 OWF43900.1 - 6.1e-06 25.8 0.5 0.3 11.1 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OWF43900.1 - 6.7e-06 26.5 0.0 0.0063 16.9 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair PH PF00169.29 OWF43900.1 - 4.5e-05 23.9 2.7 0.00032 21.2 0.1 2.8 2 0 0 2 2 2 1 PH domain EF-hand_8 PF13833.6 OWF43900.1 - 0.0012 18.7 0.5 0.57 10.1 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF43900.1 - 0.0042 16.5 0.2 1 9.0 0.1 2.8 2 0 0 2 2 2 1 EF hand PAS_11 PF14598.6 OWF43900.1 - 0.076 13.1 6.8 0.29 11.3 6.8 2.1 1 0 0 1 1 1 0 PAS domain BBS1 PF14779.6 OWF43900.1 - 5.1 6.5 10.7 16 4.8 9.6 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 1 ADH_N PF08240.12 OWF43901.1 - 4.1e-08 33.1 1.5 4.1e-08 33.1 1.5 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OWF43901.1 - 7.2e-07 29.2 0.2 2.3e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF43901.1 - 2.1e-05 25.6 0.0 6.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Jagunal PF07086.12 OWF43902.1 - 4e-43 147.7 0.4 4e-43 147.7 0.4 1.3 2 0 0 2 2 2 1 Jagunal, ER re-organisation during oogenesis SIMPL PF04402.14 OWF43903.1 - 2.3e-23 83.7 0.6 2.9e-23 83.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Prefoldin_3 PF13758.6 OWF43903.1 - 0.13 12.4 4.0 1.1 9.4 0.3 2.8 2 1 1 3 3 3 0 Prefoldin subunit Gal_Lectin PF02140.18 OWF43904.1 - 0.0074 16.7 4.4 0.018 15.5 4.4 1.7 1 0 0 1 1 1 1 Galactose binding lectin domain DUF3592 PF12158.8 OWF43904.1 - 0.11 12.5 0.0 6.6 6.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) Pex14_N PF04695.13 OWF43904.1 - 0.91 10.2 4.3 8.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EphA2_TM PF14575.6 OWF43904.1 - 5.8 7.9 5.4 1.1 10.1 0.2 2.7 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DOMON PF03351.17 OWF43905.1 - 1.3e-108 358.2 49.2 4.4e-17 62.5 0.1 7.2 7 0 0 7 7 7 7 DOMON domain DUF1181 PF06680.11 OWF43905.1 - 6.4e-05 22.8 9.2 18 5.2 0.1 6.4 7 0 0 7 7 7 1 Protein of unknown function (DUF1181) Ni_hydr_CYTB PF01292.20 OWF43905.1 - 0.0052 16.4 9.9 0.48 10.0 0.2 2.9 1 1 2 3 3 3 3 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 OWF43905.1 - 0.0073 16.5 10.4 0.016 15.4 10.4 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 SKICH PF17751.1 OWF43905.1 - 0.028 15.0 7.2 80 3.9 0.0 6.7 7 0 0 7 7 7 0 SKICH domain TIR-like PF10137.9 OWF43905.1 - 0.067 13.2 1.3 18 5.3 0.1 4.2 4 0 0 4 4 4 0 Predicted nucleotide-binding protein containing TIR-like domain NTPase_1 PF03266.15 OWF43905.1 - 0.069 13.1 1.6 21 5.0 0.0 4.2 5 0 0 5 5 5 0 NTPase DUF4079 PF13301.6 OWF43905.1 - 3.1 7.9 6.2 10 6.3 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Toxin_R_bind_N PF07953.12 OWF43905.1 - 6.6 6.4 19.2 46 3.7 0.2 5.5 5 0 0 5 5 5 0 Clostridium neurotoxin, N-terminal receptor binding DOMON PF03351.17 OWF43906.1 - 2e-18 66.8 0.1 3.4e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 OWF43906.1 - 0.00014 22.0 7.7 0.00014 22.0 7.7 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 OWF43906.1 - 0.016 15.1 16.1 0.1 12.6 2.5 3.1 2 1 1 3 3 3 0 Tight junction protein, Claudin-like Spore_YhaL PF14147.6 OWF43906.1 - 0.27 11.0 2.3 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Sporulation protein YhaL DOMON PF03351.17 OWF43907.1 - 2.8e-09 37.2 0.1 4.1e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 DOMON domain DOMON PF03351.17 OWF43908.1 - 3.7e-08 33.6 0.0 5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 DOMON domain DOMON PF03351.17 OWF43909.1 - 5.7e-33 113.8 4.7 1.5e-19 70.5 1.0 2.4 2 0 0 2 2 2 2 DOMON domain Cytochrom_B561 PF03188.16 OWF43909.1 - 9.4e-07 29.0 8.5 1.7e-06 28.2 8.5 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 OWF43909.1 - 0.00025 21.0 13.5 0.0081 16.1 5.9 2.5 1 1 1 2 2 2 2 Tight junction protein, Claudin-like Peptidase_C25_C PF03785.14 OWF43909.1 - 1.1 9.1 3.8 0.68 9.8 0.2 2.4 2 1 1 3 3 3 0 Peptidase family C25, C terminal ig-like domain Phytochelatin PF05023.14 OWF43910.1 - 2.8e-90 301.2 0.0 4.9e-90 300.4 0.0 1.4 1 0 0 1 1 1 1 Phytochelatin synthase Phytochelatin_C PF09328.10 OWF43910.1 - 0.0012 18.2 0.7 0.15 11.4 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1984) Peptidase_C39_2 PF13529.6 OWF43910.1 - 0.038 14.5 0.0 13 6.3 0.0 2.9 3 0 0 3 3 3 0 Peptidase_C39 like family MAP7 PF05672.11 OWF43911.1 - 4.6e-19 68.7 70.3 4.6e-19 68.7 70.3 3.6 4 0 0 4 4 4 2 MAP7 (E-MAP-115) family AAA PF00004.29 OWF43912.1 - 1.7e-30 106.2 0.0 4.5e-30 104.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF43912.1 - 1.7e-12 46.9 0.2 3.3e-11 42.8 0.2 2.5 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 OWF43912.1 - 2.3e-12 46.7 0.1 6.3e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 OWF43912.1 - 8.3e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OWF43912.1 - 5.9e-05 23.3 0.2 0.00013 22.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 OWF43912.1 - 6.5e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OWF43912.1 - 8.4e-05 23.0 0.0 0.013 15.9 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 OWF43912.1 - 0.00048 19.4 0.0 0.00078 18.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 OWF43912.1 - 0.001 18.5 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF43912.1 - 0.001 19.1 0.1 0.0025 17.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 OWF43912.1 - 0.0016 18.4 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OWF43912.1 - 0.0028 17.4 0.1 0.0068 16.2 0.1 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OWF43912.1 - 0.0062 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OWF43912.1 - 0.0084 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 OWF43912.1 - 0.0092 16.3 0.2 0.077 13.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 OWF43912.1 - 0.028 13.8 0.8 2.8 7.2 0.1 2.9 2 1 1 3 3 3 0 KaiC AAA_18 PF13238.6 OWF43912.1 - 0.028 14.9 0.2 0.066 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 OWF43912.1 - 0.057 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 OWF43912.1 - 0.06 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 OWF43912.1 - 0.062 13.7 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OWF43912.1 - 0.066 12.9 0.2 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OWF43912.1 - 0.066 13.4 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain MHCassoc_trimer PF08831.10 OWF43912.1 - 0.075 13.1 0.2 0.075 13.1 0.2 2.2 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain RNA_helicase PF00910.22 OWF43912.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OWF43912.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OWF43912.1 - 0.18 11.3 0.4 0.67 9.5 0.3 1.9 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 OWF43913.1 - 7.6e-10 39.2 1.5 2.1e-05 25.2 0.4 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF43913.1 - 0.00082 19.6 0.0 1.2 9.5 0.0 3.8 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3485 PF11984.8 OWF43913.1 - 0.022 14.5 0.8 0.045 13.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) HSBP1 PF06825.12 OWF43913.1 - 0.091 12.6 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 OB_NTP_bind PF07717.16 OWF43914.1 - 3.1e-21 75.5 0.0 7.4e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OWF43914.1 - 2.6e-20 72.7 0.2 5.9e-20 71.6 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OWF43914.1 - 3.6e-12 46.6 0.0 1.5e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF43914.1 - 2.7e-08 33.8 0.1 5.5e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF43914.1 - 0.00016 21.9 0.1 0.00063 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OWF43914.1 - 0.023 13.8 0.0 0.086 11.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 OWF43914.1 - 0.031 14.6 0.1 0.092 13.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 OWF43914.1 - 0.067 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 OWF43914.1 - 0.074 13.6 0.3 5.7 7.5 0.3 2.6 1 1 0 1 1 1 0 ABC transporter Lebercilin PF15619.6 OWF43915.1 - 4.7e-53 179.7 45.7 4.7e-53 179.7 45.7 3.5 3 1 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Shugoshin_N PF07558.11 OWF43915.1 - 0.0035 17.2 5.5 0.024 14.5 3.2 3.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Ribosomal_L24e PF01246.20 OWF43916.1 - 1e-30 105.8 0.9 1e-30 105.8 0.9 3.4 4 0 0 4 4 4 1 Ribosomal protein L24e zf-RING_13 PF17977.1 OWF43916.1 - 0.089 12.9 10.0 45 4.3 0.5 6.7 4 1 1 5 5 5 0 RING/Ubox like zinc-binding domain DDHD PF02862.17 OWF43916.1 - 0.19 11.9 2.4 0.31 11.2 2.4 1.2 1 0 0 1 1 1 0 DDHD domain LRR_4 PF12799.7 OWF43917.1 - 9.4e-13 48.1 26.2 0.0014 19.0 4.2 5.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF43917.1 - 6.5e-12 45.3 9.3 1.1e-08 34.7 2.3 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OWF43917.1 - 5.4e-10 38.9 26.7 0.00017 21.3 6.2 4.5 2 2 2 4 4 4 4 Leucine rich repeat fn3 PF00041.21 OWF43917.1 - 1.1e-05 25.6 0.1 3.8e-05 23.9 0.1 2.0 1 0 0 1 1 1 1 Fibronectin type III domain IQ PF00612.27 OWF43917.1 - 4e-05 23.0 0.7 0.00013 21.5 0.7 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif SNF2_N PF00176.23 OWF43918.1 - 1.3e-55 188.5 0.1 2.3e-55 187.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF43918.1 - 3.4e-19 69.2 0.2 2.9e-18 66.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF43918.1 - 1.6e-10 41.2 0.0 6.9e-10 39.2 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OWF43918.1 - 4.3e-09 36.0 1.1 3.4e-05 23.2 0.6 2.7 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 OWF43918.1 - 1.7e-06 27.4 1.0 3.3e-06 26.5 0.4 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CUE PF02845.16 OWF43918.1 - 0.0021 17.7 0.2 3.3 7.5 0.0 2.6 2 0 0 2 2 2 2 CUE domain DUF5390 PF17365.2 OWF43918.1 - 6.6 7.0 6.0 1.1 9.5 1.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5390) MRP-S28 PF10213.9 OWF43919.1 - 7.5e-19 68.4 0.1 1.7e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ank_2 PF12796.7 OWF43920.1 - 1.9e-31 108.5 2.5 6.3e-16 58.7 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF43920.1 - 4.6e-29 100.4 3.4 1.1e-13 51.4 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PRKG1_interact PF15898.5 OWF43920.1 - 6.4e-27 94.4 20.6 6.4e-27 94.4 20.6 7.2 5 2 1 6 6 6 1 cGMP-dependent protein kinase interacting domain Ank_3 PF13606.6 OWF43920.1 - 2.6e-23 79.5 1.4 1.9e-05 24.7 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 OWF43920.1 - 2.8e-22 78.1 6.0 0.00019 21.8 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF43920.1 - 1.6e-21 76.1 6.1 9.9e-11 41.7 0.4 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DUF2408 PF10303.9 OWF43920.1 - 0.0072 16.9 7.7 0.0072 16.9 7.7 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2408) Biopterin_H PF00351.21 OWF43921.1 - 2.1e-172 572.6 0.0 2.6e-172 572.4 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 OWF43921.1 - 0.00016 21.3 0.0 0.00047 19.9 0.0 1.8 2 0 0 2 2 2 1 ACT domain Laminin_II PF06009.12 OWF43922.1 - 0.0015 18.6 0.1 0.0017 18.4 0.1 1.1 1 0 0 1 1 1 1 Laminin Domain II IFT57 PF10498.9 OWF43922.1 - 0.0015 17.5 7.6 0.0016 17.5 7.6 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF16 PF01519.16 OWF43922.1 - 0.032 14.7 0.1 0.041 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 FliD_C PF07195.12 OWF43922.1 - 0.1 12.0 5.0 0.22 10.9 5.0 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FlxA PF14282.6 OWF43922.1 - 0.11 12.4 1.8 0.94 9.5 2.2 1.9 1 1 0 1 1 1 0 FlxA-like protein Filo_VP35 PF02097.15 OWF43922.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Filoviridae VP35 Bap31_Bap29_C PF18035.1 OWF43922.1 - 0.21 11.6 0.6 2.5 8.2 0.6 2.2 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5344 PF17279.2 OWF43922.1 - 0.74 10.4 5.6 2.4 8.8 0.4 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) EF-G-binding_N PF07299.11 OWF43922.1 - 2.6 8.7 18.6 2.2 8.9 2.1 2.9 1 1 2 3 3 3 0 Elongation factor G-binding protein, N-terminal Ribosomal_S4 PF00163.19 OWF43922.1 - 2.8 8.9 11.0 1.6e+02 3.3 11.0 2.4 1 1 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain z-alpha PF02295.17 OWF43922.1 - 2.8 8.0 8.1 16 5.6 2.2 3.0 1 1 1 2 2 2 0 Adenosine deaminase z-alpha domain Biopterin_H PF00351.21 OWF43924.1 - 4.5e-163 542.0 0.1 5.3e-162 538.5 0.2 2.0 2 0 0 2 2 2 1 Biopterin-dependent aromatic amino acid hydroxylase ACT_4 PF13291.6 OWF43924.1 - 0.0019 18.7 0.1 0.0038 17.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain Profilin PF00235.19 OWF43925.1 - 3.9e-13 49.8 0.0 5.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Profilin Peptidase_M24 PF00557.24 OWF43926.1 - 2.3e-40 138.5 0.0 3.7e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 OWF43926.1 - 1.2e-38 132.8 0.0 2.3e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 OWF43926.1 - 1.5e-20 73.0 0.2 3.2e-20 71.9 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OWF43926.1 - 1e-12 48.8 0.2 1.2e-09 38.9 0.0 3.1 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain SCP-1 PF05483.12 OWF43926.1 - 0.046 11.7 0.1 0.071 11.1 0.1 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) TMEM154 PF15102.6 OWF43927.1 - 0.011 15.6 0.7 0.014 15.3 0.2 1.5 2 0 0 2 2 2 0 TMEM154 protein family KASH PF10541.9 OWF43927.1 - 0.049 13.9 2.1 0.065 13.5 0.5 1.9 2 0 0 2 2 2 0 Nuclear envelope localisation domain SARAF PF06682.12 OWF43927.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Kazal_2 PF07648.15 OWF43928.1 - 3.4e-16 59.1 58.4 5.5e-06 26.4 8.5 4.6 4 1 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF43928.1 - 2.3e-14 53.1 43.3 1.2e-05 25.2 7.3 4.4 3 1 1 4 4 4 4 Kazal-type serine protease inhibitor domain Fip1 PF05182.13 OWF43928.1 - 0.12 11.9 0.6 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Fip1 motif BIR PF00653.21 OWF43929.1 - 2.2e-19 69.9 1.4 2.2e-19 69.9 1.4 2.6 3 0 0 3 3 3 1 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF43929.1 - 1.3e-13 50.6 11.6 3.6e-13 49.1 9.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF43929.1 - 1.4e-05 24.9 10.5 1.4e-05 24.9 10.5 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF43929.1 - 0.014 15.4 11.1 0.014 15.4 11.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 OWF43929.1 - 0.029 14.7 12.1 0.029 14.7 12.1 2.3 2 1 0 2 2 2 0 Ring finger domain Chorion_3 PF05387.11 OWF43929.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Chorion family 3 zf-C3HC PF07967.13 OWF43929.1 - 2.1 8.4 7.9 0.18 11.9 0.5 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like MFS_1 PF07690.16 OWF43930.1 - 5.4e-18 65.0 18.1 8.7e-12 44.6 0.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3925 PF13063.6 OWF43930.1 - 0.62 10.3 0.0 0.62 10.3 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3925) SNF PF00209.18 OWF43931.1 - 1.4e-211 703.8 37.4 1.6e-211 703.6 37.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF1664 PF07889.12 OWF43932.1 - 0.0025 17.8 2.1 0.0041 17.1 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OWF43932.1 - 0.0044 17.1 4.2 0.086 12.9 4.9 2.0 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.8 OWF43932.1 - 0.0055 16.1 6.8 0.0083 15.6 6.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF3150 PF11348.8 OWF43932.1 - 0.015 14.5 0.4 0.021 14.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) AviRa PF11599.8 OWF43932.1 - 0.022 14.2 1.4 0.032 13.7 1.4 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa FlaC_arch PF05377.11 OWF43932.1 - 0.05 14.0 8.6 0.1 13.0 7.9 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 OWF43932.1 - 0.24 11.5 8.1 0.17 12.0 4.9 2.3 2 1 0 2 2 2 0 bZIP transcription factor HSBP1 PF06825.12 OWF43932.1 - 0.44 10.5 5.0 0.81 9.6 2.6 2.3 1 1 0 2 2 2 0 Heat shock factor binding protein 1 YvrJ PF12841.7 OWF43932.1 - 0.56 9.8 2.4 1.2 8.7 2.4 1.6 1 0 0 1 1 1 0 YvrJ protein family Zf_RING PF16744.5 OWF43932.1 - 2.9 8.1 16.0 7.8 6.7 16.0 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger MFS_1 PF07690.16 OWF43933.1 - 3.2e-12 46.0 11.8 2.9e-05 23.2 0.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3925 PF13063.6 OWF43933.1 - 0.094 12.9 0.1 0.094 12.9 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3925) MDFI PF15316.6 OWF43933.1 - 8 6.5 9.3 0.36 10.9 2.4 2.0 2 0 0 2 2 2 0 MyoD family inhibitor Peptidase_M20 PF01546.28 OWF43934.1 - 5.8e-05 22.9 0.0 9.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OWF43934.1 - 0.0002 21.3 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain APG5 PF04106.12 OWF43935.1 - 1.5e-57 194.9 0.5 1.9e-57 194.5 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Glyco_transf_10 PF00852.19 OWF43936.1 - 4.7e-50 169.8 5.5 7.7e-50 169.0 5.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF43936.1 - 3.4e-12 46.8 0.2 1.1e-11 45.1 0.1 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_7N PF13733.6 OWF43937.1 - 8e-50 167.9 0.2 8e-50 167.9 0.2 1.8 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF43937.1 - 7.1e-33 112.1 0.7 1.6e-32 111.0 0.7 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF43937.1 - 0.00058 19.4 0.3 0.0021 17.6 0.1 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 DsrH PF04077.12 OWF43937.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 DsrH like protein Glyco_transf_10 PF00852.19 OWF43938.1 - 1.9e-47 161.2 1.6 3.1e-47 160.6 1.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF43938.1 - 1.2e-16 61.2 1.0 2.5e-16 60.1 0.1 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_7N PF13733.6 OWF43939.1 - 4.7e-51 171.9 0.1 4.7e-51 171.9 0.1 4.4 3 2 1 4 4 4 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF43939.1 - 2.3e-32 110.5 1.0 5.3e-32 109.3 1.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF3060 PF11259.8 OWF43941.1 - 7.1e-07 28.8 37.0 0.088 12.5 1.8 8.6 2 2 3 6 6 6 3 Protein of unknown function (DUF3060) Glyco_hydro_65C PF03633.15 OWF43941.1 - 0.0002 21.2 30.0 0.02 14.8 1.6 7.1 1 1 7 8 8 8 3 Glycosyl hydrolase family 65, C-terminal domain Viral_DNA_bi PF02236.17 OWF43941.1 - 0.026 14.7 7.0 3 8.1 0.0 4.7 1 1 3 5 5 5 0 Viral DNA-binding protein, all alpha domain DUF3786 PF12654.7 OWF43941.1 - 0.037 13.6 0.4 5 6.7 0.0 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF3786) Cu_amine_oxidN1 PF07833.11 OWF43941.1 - 0.052 14.0 16.8 3.9 8.0 0.7 4.7 1 1 2 3 3 3 0 Copper amine oxidase N-terminal domain UFC1 PF08694.11 OWF43941.1 - 0.14 11.8 0.2 2.7 7.6 0.0 2.5 1 1 2 3 3 3 0 Ubiquitin-fold modifier-conjugating enzyme 1 CBM_26 PF16824.5 OWF43941.1 - 0.26 11.5 5.2 2.7 8.1 1.0 3.5 1 1 4 5 5 5 0 C-terminal carbohydrate-binding module VWD PF00094.25 OWF43941.1 - 0.46 10.7 15.7 5.3 7.3 1.8 3.1 1 1 2 3 3 3 0 von Willebrand factor type D domain DUF945 PF06097.11 OWF43941.1 - 0.61 9.1 3.5 5.6 6.0 0.6 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF945) VEG PF06257.11 OWF43941.1 - 1.3 9.1 12.9 3 8.0 0.4 3.9 1 1 2 4 4 4 0 Biofilm formation stimulator VEG LPD7 PF18821.1 OWF43941.1 - 5.6 7.2 10.7 29 4.9 1.7 4.1 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 7 Clostridium_P47 PF06597.11 OWF43941.1 - 5.9 5.5 7.5 1.7 7.3 0.9 2.4 1 1 0 2 2 2 0 Clostridium P-47 protein HYR PF02494.16 OWF43941.1 - 6.4 7.2 12.9 9.2 6.7 1.4 3.7 1 1 4 5 5 5 0 HYR domain Ecotin PF03974.13 OWF43941.1 - 7.4 6.6 8.3 15 5.6 1.3 3.2 1 1 2 3 3 3 0 Ecotin Sulfotransfer_1 PF00685.27 OWF43943.1 - 9e-17 61.4 0.6 1.7e-16 60.5 0.6 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF43943.1 - 5.6e-11 43.2 0.0 1.5e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family GRIM-19 PF06212.12 OWF43943.1 - 0.019 14.9 0.2 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 GRIM-19 protein fn3 PF00041.21 OWF43944.1 - 6.7e-14 52.0 16.5 5.8e-06 26.6 1.0 5.5 5 1 1 6 6 6 4 Fibronectin type III domain PRIMA1 PF16101.5 OWF43944.1 - 0.033 14.2 0.5 0.094 12.8 0.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cadherin_C_2 PF16492.5 OWF43944.1 - 0.052 14.3 0.1 0.32 11.8 0.0 2.5 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF4767 PF15983.5 OWF43944.1 - 0.41 10.9 1.8 1.7 8.9 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4767) Podoplanin PF05808.11 OWF43944.1 - 5 7.2 6.8 47 4.0 0.0 2.6 2 0 0 2 2 2 0 Podoplanin Smg4_UPF3 PF03467.15 OWF43945.1 - 2.5e-39 135.1 1.4 2.5e-39 135.1 1.4 4.3 4 1 1 5 5 5 1 Smg-4/UPF3 family CHORD PF04968.12 OWF43946.1 - 3.9e-51 171.6 28.5 2.6e-27 95.3 5.5 2.8 3 0 0 3 3 3 2 CHORD CS PF04969.16 OWF43946.1 - 0.002 19.1 0.0 0.0044 18.0 0.0 1.7 1 0 0 1 1 1 1 CS domain BTK PF00779.19 OWF43946.1 - 0.054 13.3 15.1 0.28 11.0 0.6 3.7 2 1 0 2 2 2 0 BTK motif LRR_8 PF13855.6 OWF43947.1 - 3.3e-59 196.5 90.6 3.1e-12 46.1 3.1 6.3 1 1 7 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 OWF43947.1 - 1.1e-29 103.0 1.4 2.5e-09 37.2 0.0 3.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) 7tm_1 PF00001.21 OWF43947.1 - 1.7e-23 83.3 19.9 2.2e-23 82.9 19.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 OWF43947.1 - 6.3e-18 64.6 48.2 0.00082 19.7 1.8 7.5 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF43947.1 - 1.3e-08 34.5 18.2 0.00026 20.6 1.4 3.2 1 1 2 3 3 3 3 Leucine-rich repeat 7TM_GPCR_Srv PF10323.9 OWF43947.1 - 0.00035 20.0 9.4 0.00052 19.5 9.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv CSTF_C PF14304.6 OWF43947.1 - 0.0012 18.3 0.1 70 3.1 0.0 6.6 7 1 1 8 8 8 0 Transcription termination and cleavage factor C-terminal YcxB PF14317.6 OWF43947.1 - 0.0035 17.0 0.1 1.3e+02 2.4 0.1 5.6 3 1 3 6 6 6 0 YcxB-like protein 7TM_GPCR_Srw PF10324.9 OWF43947.1 - 0.0053 16.1 16.8 0.24 10.6 16.8 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw NosD PF05048.13 OWF43947.1 - 0.022 14.1 1.5 0.041 13.2 1.5 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF2610 PF11020.8 OWF43947.1 - 0.066 13.1 0.1 96 3.0 0.0 4.4 3 2 0 4 4 4 0 Domain of unknown function (DUF2610) LRR_1 PF00560.33 OWF43947.1 - 0.56 11.0 37.2 1.6 9.5 0.3 10.5 9 3 1 10 10 9 0 Leucine Rich Repeat SNF PF00209.18 OWF43949.1 - 1e-170 568.9 39.2 1.3e-170 568.6 39.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Gate PF07670.14 OWF43949.1 - 0.00017 21.8 2.7 0.00017 21.8 2.7 3.4 4 0 0 4 4 4 2 Nucleoside recognition Sigma70_r4_2 PF08281.12 OWF43950.1 - 1.4e-06 27.9 37.6 28 4.5 0.1 19.9 2 1 52 54 54 54 2 Sigma-70, region 4 DASH_Dam1 PF08653.10 OWF43950.1 - 0.11 12.3 59.2 86 3.0 0.1 20.0 1 1 39 40 40 40 0 DASH complex subunit Dam1 7tm_1 PF00001.21 OWF43951.1 - 0.0048 16.3 0.1 0.0078 15.6 0.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CYYR1 PF10873.8 OWF43951.1 - 7.2 7.0 6.1 7.7 7.0 5.5 1.4 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 HA PF03457.14 OWF43952.1 - 7.1e-18 64.7 13.5 1.9 8.9 0.0 11.0 1 1 7 8 8 8 8 Helicase associated domain DUF4822 PF16103.5 OWF43952.1 - 1.1e-13 51.5 16.7 0.34 11.2 0.0 6.6 1 1 6 7 7 7 7 Domain of unknown function (DUF4822) Cytotoxic PF09000.10 OWF43952.1 - 0.0019 18.5 42.7 4.4 7.7 1.0 8.5 1 1 8 9 9 9 8 Cytotoxic Acetyltransf_5 PF13444.6 OWF43952.1 - 0.68 10.7 16.4 1.3e+02 3.3 0.1 7.6 2 2 7 9 9 9 0 Acetyltransferase (GNAT) domain HA PF03457.14 OWF43953.1 - 0.00025 21.3 0.1 2.2 8.7 0.0 3.6 1 1 1 2 2 2 2 Helicase associated domain DUF4822 PF16103.5 OWF43953.1 - 0.0074 16.6 1.5 0.86 9.9 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4822) 7tm_1 PF00001.21 OWF43954.1 - 5.3e-48 163.6 16.9 7.3e-48 163.2 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF43954.1 - 4.8e-08 33.1 12.9 1.5e-07 31.5 12.9 1.8 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF43954.1 - 0.0061 16.2 15.5 0.0061 16.2 15.5 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx LCE PF14672.6 OWF43954.1 - 0.13 12.8 10.1 0.26 11.9 10.1 1.4 1 0 0 1 1 1 0 Late cornified envelope ATPgrasp_Ter PF15632.6 OWF43955.1 - 3.2e-10 39.9 0.2 2.7e-09 36.9 0.2 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 OWF43955.1 - 5.1e-07 29.4 0.0 8.2e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 OWF43955.1 - 9.8e-06 26.0 0.0 2.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp N-terminal domain zf-CCHC PF00098.23 OWF43956.1 - 0.019 15.0 12.4 0.07 13.2 4.3 2.6 2 0 0 2 2 2 0 Zinc knuckle Baculo_PEP_C PF04513.12 OWF43958.1 - 1.5 8.9 8.8 29 4.7 8.8 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Microtub_bind PF13931.6 OWF43959.1 - 4e-18 66.1 6.8 4e-18 66.1 6.8 5.3 2 1 4 6 6 6 1 Kinesin-associated microtubule-binding FA_desaturase PF00487.24 OWF43961.1 - 2.1e-14 54.0 10.7 2.1e-14 54.0 10.7 1.9 1 1 1 2 2 2 1 Fatty acid desaturase CLTH PF10607.9 OWF43962.1 - 3.8e-30 104.7 0.0 7.9e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OWF43962.1 - 1.3e-06 28.4 0.3 3.1e-06 27.1 0.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 OWF43962.1 - 0.0025 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger DUF1664 PF07889.12 OWF43962.1 - 0.013 15.5 1.3 0.036 14.1 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) zf-RING_2 PF13639.6 OWF43962.1 - 0.016 15.6 1.3 0.035 14.5 0.3 2.2 2 0 0 2 2 2 0 Ring finger domain Trimer_CC PF08954.11 OWF43962.1 - 0.025 14.1 0.1 0.075 12.6 0.1 1.8 2 0 0 2 2 2 0 Trimerisation motif KASH_CCD PF14662.6 OWF43962.1 - 0.074 12.9 0.6 0.13 12.1 0.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH zf-RING_5 PF14634.6 OWF43962.1 - 0.12 12.4 0.2 0.31 11.0 0.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain WD40 PF00400.32 OWF43963.1 - 0.00028 21.6 2.3 1.4 10.0 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40_like PF17005.5 OWF43963.1 - 0.066 12.5 0.0 0.74 9.1 0.0 2.2 1 1 0 2 2 2 0 WD40-like domain zf-B_box PF00643.24 OWF43966.1 - 1e-12 48.0 20.7 1.3e-06 28.5 9.5 2.2 2 0 0 2 2 2 2 B-box zinc finger DUF5082 PF16888.5 OWF43966.1 - 0.049 13.9 4.5 0.085 13.1 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) PIN_8 PF18476.1 OWF43966.1 - 0.13 12.1 6.3 0.19 11.6 6.3 1.2 1 0 0 1 1 1 0 PIN like domain DUF1664 PF07889.12 OWF43966.1 - 0.33 11.0 3.3 0.58 10.2 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 OWF43966.1 - 0.78 9.3 4.5 3.8 7.0 4.6 1.8 1 1 0 1 1 1 0 fzo-like conserved region Siva PF05458.12 OWF43966.1 - 0.86 9.3 12.2 2.9 7.5 1.5 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) ApoO PF09769.9 OWF43966.1 - 1.1 9.2 3.2 9.3 6.2 0.1 2.4 2 1 1 3 3 3 0 Apolipoprotein O IBR PF01485.21 OWF43966.1 - 3 8.1 17.5 1.6 9.0 4.6 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain C1_2 PF03107.16 OWF43966.1 - 4.7 7.6 19.6 1.8 8.9 4.3 2.4 2 0 0 2 2 2 0 C1 domain Spore_II_R PF09551.10 OWF43967.1 - 0.072 13.6 0.9 0.13 12.7 0.9 1.6 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF1075 PF06388.11 OWF43967.1 - 0.62 10.1 5.2 13 5.9 0.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1075) DUF1075 PF06388.11 OWF43968.1 - 0.044 13.8 8.7 35 4.5 0.1 4.5 1 1 1 4 4 4 0 Protein of unknown function (DUF1075) HydF_tetramer PF18133.1 OWF43968.1 - 0.057 13.2 5.7 0.72 9.6 2.1 3.0 1 1 1 2 2 2 0 Hydrogen maturase F tetramerization domain Ribosomal_L19e PF01280.20 OWF43968.1 - 0.21 11.7 1.7 23 5.1 0.0 3.0 1 1 2 3 3 3 0 Ribosomal protein L19e Ank_5 PF13857.6 OWF43969.1 - 6e-06 26.4 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF43969.1 - 0.00038 20.7 0.2 0.0011 19.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OWF43969.1 - 0.0011 19.5 0.0 0.0015 19.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF43969.1 - 0.0028 18.2 0.0 0.0067 17.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF43969.1 - 0.027 14.9 0.6 0.048 14.1 0.1 1.6 2 0 0 2 2 2 0 Ankyrin repeat MFS_1 PF07690.16 OWF43970.1 - 1.7e-09 37.1 39.0 2.7e-05 23.3 8.1 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily TMEM154 PF15102.6 OWF43970.1 - 0.0023 17.8 11.8 0.0056 16.6 0.0 3.5 3 1 0 4 4 4 2 TMEM154 protein family Alpha-amyl_C PF09071.10 OWF43970.1 - 0.57 10.1 2.8 25 4.8 0.7 3.1 3 0 0 3 3 3 0 Alpha-amylase, C terminal Comm PF15957.5 OWF43970.1 - 2.2 8.6 12.4 5.4 7.4 0.5 3.7 3 0 0 3 3 3 0 Commissureless Lipase_GDSL_2 PF13472.6 OWF43971.1 - 9.4e-05 22.9 0.0 0.00012 22.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DinB_2 PF12867.7 OWF43971.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 DinB superfamily VEG PF06257.11 OWF43972.1 - 7.5 6.7 10.8 9.8 6.3 0.7 2.3 1 1 1 2 2 2 0 Biofilm formation stimulator VEG DUF4806 PF16064.5 OWF43974.1 - 4.8e-06 26.8 0.6 7.1e-06 26.2 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) GT-D PF08759.11 OWF43974.1 - 0.02 14.6 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Prenyltransf PF01255.19 OWF43974.1 - 0.13 11.8 1.1 0.26 10.8 1.1 1.5 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase IL2 PF00715.17 OWF43974.1 - 0.13 12.2 1.8 0.16 11.9 1.0 1.5 1 1 0 1 1 1 0 Interleukin 2 BTB_2 PF02214.22 OWF43975.1 - 5.1e-20 71.6 0.1 2.2e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.31 OWF43975.1 - 2.4e-19 69.5 29.7 3.7e-19 68.9 29.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF43975.1 - 3e-07 30.3 10.1 3e-07 30.3 10.1 2.7 3 0 0 3 3 3 1 Ion channel TPR_1 PF00515.28 OWF43976.1 - 1.3e-32 110.2 14.2 5.8e-05 22.7 0.1 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 OWF43976.1 - 7.3e-26 88.2 12.7 0.0028 17.6 0.0 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 OWF43976.1 - 3e-25 87.6 5.9 8.1e-06 25.4 0.1 8.0 6 3 2 8 8 8 4 TPR repeat TPR_8 PF13181.6 OWF43976.1 - 5e-21 73.1 3.9 0.03 14.5 0.0 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OWF43976.1 - 1.6e-12 47.4 8.6 0.00097 19.2 0.0 6.5 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF43976.1 - 2.4e-11 43.2 16.2 0.31 11.5 0.0 9.0 10 1 1 11 11 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF43976.1 - 3.6e-11 42.9 13.2 0.00021 21.8 0.7 7.8 4 3 3 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF43976.1 - 9.1e-11 42.2 5.7 0.0003 21.4 0.1 6.5 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF43976.1 - 7.4e-10 39.2 15.4 0.0058 17.1 0.4 6.3 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF43976.1 - 1.2e-09 38.3 15.6 0.0011 19.2 0.0 6.7 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF43976.1 - 3.6e-06 26.6 10.5 0.22 11.7 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 OWF43976.1 - 3.3e-05 24.1 7.4 0.21 12.0 0.2 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat MAS20 PF02064.15 OWF43976.1 - 0.00084 19.4 0.3 0.44 10.6 0.0 3.9 4 0 0 4 4 3 1 MAS20 protein import receptor Rapsyn_N PF10579.9 OWF43976.1 - 0.0012 18.9 0.2 0.011 15.8 0.0 2.7 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region HrpB1_HrpK PF09613.10 OWF43976.1 - 0.0039 16.8 0.9 2 8.1 0.0 3.3 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 OWF43976.1 - 0.0064 15.7 7.3 7.2 5.7 0.3 4.7 2 1 3 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 OWF43976.1 - 0.0073 16.7 5.8 7.5 7.0 0.0 4.3 2 1 2 4 4 4 0 Bacterial transcriptional activator domain TPR_21 PF09976.9 OWF43976.1 - 0.011 15.5 1.6 0.011 15.5 1.6 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF1525 PF07511.11 OWF43976.1 - 0.012 15.7 0.2 5.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) DUF2225 PF09986.9 OWF43976.1 - 0.016 15.0 0.7 0.21 11.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 OWF43976.1 - 0.023 14.9 12.9 0.26 11.6 0.0 5.1 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 UPF0449 PF15136.6 OWF43976.1 - 0.1 13.0 3.9 9 6.8 0.2 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 CCDC53 PF10152.9 OWF43976.1 - 0.93 9.9 6.4 21 5.5 3.1 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TPR_6 PF13174.6 OWF43976.1 - 2.1 9.2 17.4 7.9 7.4 0.0 7.6 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF43976.1 - 3.8 6.8 7.2 1.3 8.3 1.1 3.0 2 2 0 2 2 2 0 MalT-like TPR region TPR_4 PF07721.14 OWF43976.1 - 9.2 7.2 8.0 7.6 7.5 1.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat ASH PF15780.5 OWF43977.1 - 1.4e-07 31.6 0.1 3.3 8.0 0.0 6.3 1 1 7 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CBM49 PF09478.10 OWF43977.1 - 3e-05 24.2 4.6 13 6.1 0.2 6.4 1 1 4 6 6 6 2 Carbohydrate binding domain CBM49 DUF930 PF06059.12 OWF43977.1 - 1.1 9.8 6.6 24 5.5 0.1 4.6 1 1 2 5 5 5 0 Domain of Unknown Function (DUF930) 7tm_1 PF00001.21 OWF43978.1 - 2.4e-13 50.0 13.5 3.2e-13 49.6 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF43978.1 - 6.9e-11 42.0 20.4 1.1e-09 38.1 20.4 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Ank_2 PF12796.7 OWF43980.1 - 1.7e-16 60.6 1.4 2.3e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF43980.1 - 1.2e-11 44.6 0.3 0.015 15.6 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF43980.1 - 1.2e-10 40.6 0.1 0.017 15.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OWF43980.1 - 9.3e-09 35.7 0.9 0.035 14.7 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF43980.1 - 7.4e-05 23.0 4.5 19 5.9 2.5 4.3 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OWF43981.1 - 0.0077 16.8 0.5 0.023 15.3 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) NACHT PF05729.12 OWF43982.1 - 0.00049 20.1 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OWF43982.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.7 OWF43983.1 - 2.8e-14 53.5 16.0 1.4e-07 32.0 1.8 5.8 4 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF43983.1 - 5e-10 39.7 6.3 0.00015 22.2 0.2 6.4 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF43983.1 - 7.7e-08 32.5 3.5 0.13 12.7 0.3 5.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF43983.1 - 2.2e-06 27.5 2.2 7.8 7.4 0.0 7.4 7 0 0 7 7 7 2 Ankyrin repeat NACHT PF05729.12 OWF43983.1 - 0.0002 21.3 0.0 0.00054 19.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 OWF43983.1 - 0.43 11.1 11.8 40 4.9 0.2 6.1 6 0 0 6 6 6 0 Ankyrin repeat Fer4_11 PF13247.6 OWF43984.1 - 0.09 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain UNC-50 PF05216.13 OWF43985.1 - 3.6e-90 301.4 20.3 4.2e-90 301.2 20.3 1.0 1 0 0 1 1 1 1 UNC-50 family EphA2_TM PF14575.6 OWF43986.1 - 0.08 13.8 0.5 0.16 12.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-C3HC4 PF00097.25 OWF43987.1 - 4.2e-06 26.5 14.7 1.7e-05 24.6 14.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF43987.1 - 3.6e-05 23.7 14.1 0.00013 21.9 14.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF43987.1 - 6.2e-05 23.1 16.0 0.00018 21.6 16.0 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF43987.1 - 0.00012 22.0 13.8 0.00045 20.1 13.8 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF43987.1 - 0.00016 22.0 14.2 0.00016 22.0 14.2 2.8 3 0 0 3 3 1 1 Ring finger domain NAP PF00956.18 OWF43987.1 - 0.00028 20.2 0.4 0.00045 19.5 0.4 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) zf-C3HC4_2 PF13923.6 OWF43987.1 - 0.0016 18.3 13.8 0.0054 16.5 13.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AKNA PF12443.8 OWF43987.1 - 0.0067 17.1 2.6 0.019 15.6 2.6 1.8 1 0 0 1 1 1 1 AT-hook-containing transcription factor zf-C3HC4_3 PF13920.6 OWF43987.1 - 0.011 15.6 12.0 0.011 15.6 12.0 2.4 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) FlgN PF05130.12 OWF43987.1 - 0.017 15.6 2.8 0.017 15.6 2.8 2.3 1 1 0 2 2 2 0 FlgN protein zf-B_box PF00643.24 OWF43987.1 - 0.027 14.6 1.9 0.027 14.6 1.9 3.3 2 1 0 2 2 2 0 B-box zinc finger XhlA PF10779.9 OWF43987.1 - 0.031 14.5 7.2 0.2 11.9 2.3 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Not3 PF04065.15 OWF43987.1 - 0.049 13.1 5.6 0.1 12.0 5.6 1.5 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF1804 PF08822.11 OWF43987.1 - 0.066 13.2 0.7 0.12 12.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF573 PF04504.14 OWF43987.1 - 0.069 13.8 1.1 0.29 11.8 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF573 She9_MDM33 PF05546.11 OWF43987.1 - 0.12 12.1 5.0 0.23 11.3 5.0 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family LPP PF04728.13 OWF43987.1 - 0.48 10.8 4.3 0.38 11.2 0.6 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper NHL PF01436.21 OWF43987.1 - 0.52 10.5 6.9 9 6.5 0.3 4.4 5 0 0 5 5 4 0 NHL repeat BAR PF03114.18 OWF43987.1 - 0.68 9.5 6.0 0.64 9.6 4.2 1.8 1 1 0 1 1 1 0 BAR domain DUF1664 PF07889.12 OWF43987.1 - 0.8 9.7 9.7 8.8 6.4 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_6 PF14835.6 OWF43987.1 - 0.98 9.3 16.9 0.15 11.9 9.5 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein EzrA PF06160.12 OWF43987.1 - 1.1 7.3 9.1 0.68 8.0 5.5 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 OWF43987.1 - 1.4 8.4 7.1 2.4 7.7 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 OWF43987.1 - 2.1 9.1 5.8 5.8 7.7 2.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 OWF43987.1 - 2.3 8.4 12.9 3.3 7.9 11.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prok-RING_4 PF14447.6 OWF43987.1 - 2.3 8.1 15.7 8.1 6.4 15.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF948 PF06103.11 OWF43987.1 - 3 8.2 5.5 23 5.3 4.0 2.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 OWF43987.1 - 4.3 7.6 8.5 2.5 8.3 4.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 OWF43987.1 - 5.2 7.6 7.7 0.45 11.0 2.8 1.8 2 0 0 2 2 1 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 OWF43987.1 - 6.7 6.8 12.9 1.7 8.7 8.9 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WW PF00397.26 OWF43988.1 - 1e-06 28.7 0.3 2.1e-06 27.7 0.3 1.5 1 0 0 1 1 1 1 WW domain Ets PF00178.22 OWF43989.1 - 6.4e-37 125.9 0.7 1.4e-36 124.8 0.7 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 OWF43989.1 - 5.1e-27 93.7 0.5 9.1e-27 92.9 0.5 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Methyltransf_7 PF03492.15 OWF43990.1 - 4.4e-26 91.9 0.0 5.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Ig_2 PF13895.6 OWF43991.1 - 2.3e-11 43.8 15.0 2.9e-06 27.5 0.5 4.1 4 1 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.6 OWF43991.1 - 5.7e-09 36.4 16.0 4.5e-06 27.2 1.4 4.4 5 0 0 5 5 5 3 Immunoglobulin domain fn3 PF00041.21 OWF43991.1 - 1e-08 35.4 0.3 5.1e-08 33.1 0.0 2.4 2 0 0 2 2 1 1 Fibronectin type III domain C2-set_2 PF08205.12 OWF43991.1 - 2.2e-08 34.0 7.1 5.6e-08 32.7 0.5 3.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 OWF43991.1 - 7.7e-05 23.0 1.4 0.5 10.8 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 OWF43991.1 - 0.0002 21.9 0.1 0.00073 20.1 0.1 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain I-set PF07679.16 OWF43991.1 - 0.0042 17.1 2.6 1.1 9.3 0.3 4.5 4 1 0 4 4 4 1 Immunoglobulin I-set domain ig PF00047.25 OWF43991.1 - 0.0053 16.9 12.4 1.6 8.9 0.5 4.5 4 1 0 4 4 4 2 Immunoglobulin domain CHRD PF07452.12 OWF43991.1 - 0.022 15.7 0.5 0.37 11.8 0.4 2.4 2 0 0 2 2 2 0 CHRD domain ECSCR PF15820.5 OWF43991.1 - 0.025 14.4 0.8 0.099 12.5 0.2 2.4 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator OSTbeta PF15048.6 OWF43991.1 - 0.052 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4834 PF16118.5 OWF43991.1 - 0.072 14.1 0.0 0.15 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ig_4 PF16680.5 OWF43991.1 - 0.11 12.8 1.2 0.58 10.5 0.0 2.8 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain TMEM154 PF15102.6 OWF43991.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.9 3 0 0 3 3 3 0 TMEM154 protein family ASH PF15780.5 OWF43991.1 - 1.2 9.3 4.7 0.81 9.9 0.1 3.1 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Glycophorin_A PF01102.18 OWF43991.1 - 1.7 8.9 4.5 7 6.9 0.0 3.1 3 0 0 3 3 3 0 Glycophorin A TSP_1 PF00090.19 OWF43992.1 - 0.0037 17.4 4.5 0.011 15.9 4.5 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain Beta_helix PF13229.6 OWF43992.1 - 0.0075 16.1 7.8 0.027 14.3 2.9 3.5 2 1 0 2 2 2 1 Right handed beta helix region zf-H2C2_2 PF13465.6 OWF43993.1 - 5.3e-47 156.2 57.3 2.9e-07 30.6 0.3 10.3 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 OWF43993.1 - 2.6e-39 131.5 66.5 6.7e-05 23.1 1.2 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF43993.1 - 2.9e-29 99.2 64.4 0.00058 20.5 0.9 9.6 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 OWF43993.1 - 7.2e-16 58.0 54.0 0.0077 16.6 0.1 10.0 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF43993.1 - 8.6e-11 41.8 41.8 0.044 14.1 0.3 9.4 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OWF43993.1 - 1.9e-07 31.3 33.7 0.0036 17.6 0.8 5.8 3 1 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OWF43993.1 - 8.8e-06 25.6 54.3 0.059 13.4 0.0 9.6 9 0 0 9 9 9 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OWF43993.1 - 0.0088 16.1 30.7 0.17 12.0 0.8 5.9 5 1 0 5 5 5 2 Zinc ribbon domain zf-BED PF02892.15 OWF43993.1 - 0.23 11.5 50.9 0.21 11.6 3.2 8.8 3 3 5 8 8 8 0 BED zinc finger BolA PF01722.18 OWF43993.1 - 4.5 7.6 8.4 3.3 8.1 0.1 4.0 4 1 1 5 5 5 0 BolA-like protein DUF2180 PF09947.9 OWF43993.1 - 4.5 7.3 20.8 5.8 7.0 0.7 4.5 2 1 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2180) SSF PF00474.17 OWF43994.1 - 9.9e-33 113.6 33.5 2.2e-32 112.5 33.5 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family RFX_DNA_binding PF02257.15 OWF43995.1 - 8.9e-33 112.8 0.2 2.5e-32 111.3 0.2 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 OWF43995.1 - 0.00089 19.7 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Poxvirus D5 protein-like Trypan_PARP PF05887.11 OWF43998.1 - 0.0058 16.6 3.2 0.0095 15.9 3.2 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Death PF00531.22 OWF43999.1 - 5.7e-08 32.8 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Death domain SH2 PF00017.24 OWF43999.1 - 0.00042 20.4 0.4 0.0015 18.6 0.4 2.0 1 0 0 1 1 1 1 SH2 domain DUF3060 PF11259.8 OWF43999.1 - 0.81 9.4 10.0 6.6 6.5 3.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3060) Sulfotransfer_1 PF00685.27 OWF44000.1 - 5.9e-15 55.5 0.3 7.5e-15 55.1 0.3 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF44000.1 - 2.4e-13 51.0 0.1 3.4e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 OWF44000.1 - 0.03 14.2 0.1 0.07 13.0 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase domain Fasciclin PF02469.22 OWF44001.1 - 1.6e-47 160.9 0.1 1.4e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 OWF44002.1 - 1e-49 168.0 0.2 3.7e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain 7tm_1 PF00001.21 OWF44003.1 - 6.8e-39 133.8 12.9 9.2e-39 133.3 12.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44003.1 - 2e-10 40.7 7.9 2e-10 40.7 7.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF44003.1 - 4e-06 26.4 16.6 1e-05 25.1 16.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PSI_PsaF PF02507.15 OWF44003.1 - 0.12 12.2 0.0 0.82 9.5 0.0 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III HlyIII PF03006.20 OWF44004.1 - 1.2e-35 123.3 22.9 1.8e-35 122.7 22.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 OWF44005.1 - 2.2e-34 119.2 22.9 2.2e-34 119.2 22.9 1.4 2 0 0 2 2 2 1 Haemolysin-III related DUF4491 PF14898.6 OWF44005.1 - 0.47 10.9 4.8 0.4 11.2 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) AAA PF00004.29 OWF44006.1 - 9e-73 242.9 0.0 4.5e-38 130.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF44006.1 - 6.4e-29 99.5 1.0 1.9e-13 50.0 0.7 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OWF44006.1 - 8e-13 49.1 3.4 0.00038 20.9 0.2 4.1 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 OWF44006.1 - 1e-12 48.1 0.0 2.7e-06 27.2 0.0 3.9 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF44006.1 - 2.8e-10 40.3 0.1 0.00015 21.7 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OWF44006.1 - 8.8e-08 32.4 0.0 0.0033 17.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 OWF44006.1 - 1.6e-07 30.9 0.0 0.0058 15.9 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_2 PF07724.14 OWF44006.1 - 2.3e-07 31.1 0.0 0.013 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OWF44006.1 - 2.1e-06 27.8 0.0 0.031 14.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 OWF44006.1 - 1.2e-05 24.7 0.0 0.34 10.0 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_22 PF13401.6 OWF44006.1 - 2.1e-05 24.8 3.0 0.051 13.8 0.1 4.3 2 2 1 3 3 3 1 AAA domain TsaE PF02367.17 OWF44006.1 - 4e-05 23.6 0.1 0.036 14.1 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OWF44006.1 - 0.00015 22.1 0.0 0.19 12.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 OWF44006.1 - 0.0002 21.3 1.5 0.88 9.5 0.0 3.9 4 0 0 4 4 4 1 NACHT domain AAA_11 PF13086.6 OWF44006.1 - 0.00029 20.7 0.0 0.054 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OWF44006.1 - 0.00032 20.7 2.1 0.69 9.8 0.0 3.1 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_18 PF13238.6 OWF44006.1 - 0.00036 21.1 0.0 0.11 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OWF44006.1 - 0.00088 19.6 0.5 0.18 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OWF44006.1 - 0.00096 18.7 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NTPase_1 PF03266.15 OWF44006.1 - 0.0012 18.7 0.7 3.3 7.6 0.1 3.4 3 1 0 3 3 3 2 NTPase AAA_3 PF07726.11 OWF44006.1 - 0.0036 17.1 0.0 1.1 9.1 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OWF44006.1 - 0.0047 16.9 0.1 2.9 7.9 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.18 OWF44006.1 - 0.011 15.5 0.0 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 OWF44006.1 - 0.013 14.9 0.3 4.1 6.7 0.0 2.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OWF44006.1 - 0.014 15.0 0.3 4.1 6.9 0.1 2.9 2 1 1 3 3 3 0 AAA domain He_PIG_assoc PF10632.9 OWF44006.1 - 0.019 14.7 0.1 0.044 13.4 0.1 1.7 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase ABC_tran PF00005.27 OWF44006.1 - 0.024 15.2 0.0 4.6 7.8 0.0 2.9 2 1 1 3 3 2 0 ABC transporter MCM PF00493.23 OWF44006.1 - 0.026 13.6 0.0 0.56 9.3 0.0 2.7 3 0 0 3 3 2 0 MCM P-loop domain AAA_30 PF13604.6 OWF44006.1 - 0.032 13.9 0.9 0.98 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OWF44006.1 - 0.038 13.7 0.1 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OWF44006.1 - 0.087 12.1 0.6 4.8 6.4 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 OWF44006.1 - 0.089 12.6 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 OWF44006.1 - 0.096 13.0 1.9 2.2 8.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain Homez PF11569.8 OWF44006.1 - 0.1 12.1 0.2 5.3 6.6 0.0 3.2 3 1 1 4 4 2 0 Homeodomain leucine-zipper encoding, Homez ATPase_2 PF01637.18 OWF44006.1 - 0.11 12.4 0.0 6.6 6.6 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OWF44006.1 - 0.12 12.1 0.1 7.7 6.2 0.0 3.5 2 2 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 OWF44006.1 - 0.15 12.2 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 OWF44006.1 - 0.18 11.5 0.7 9.6 5.9 0.1 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF2205 PF10224.9 OWF44006.1 - 0.23 11.5 0.5 1.1 9.3 0.1 2.4 3 0 0 3 3 2 0 Short coiled-coil protein Ribosomal_L37 PF08561.10 OWF44007.1 - 3.5e-08 34.0 1.9 4.7e-08 33.6 1.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 HDC PF02329.16 OWF44007.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Histidine carboxylase PI chain cobW PF02492.19 OWF44008.1 - 2.1e-30 105.6 0.0 2.5e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OWF44008.1 - 0.00041 19.4 0.2 0.51 9.3 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OWF44008.1 - 0.00085 19.4 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 OWF44008.1 - 0.0058 17.2 0.0 0.009 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OWF44008.1 - 0.0087 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 OWF44008.1 - 0.028 14.8 0.0 7.4 7.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.13 OWF44008.1 - 0.034 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 OWF44008.1 - 0.042 14.4 0.0 0.075 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 OWF44008.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 OWF44008.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.29 OWF44008.1 - 0.099 13.1 0.1 0.23 11.9 0.0 1.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 OWF44008.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 OWF44008.1 - 0.12 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 OWF44008.1 - 0.17 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C2H2 PF00096.26 OWF44009.1 - 7.6e-19 67.0 47.0 0.00021 21.5 1.1 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF44009.1 - 4.2e-17 61.7 38.7 4.4e-05 23.7 1.0 8.4 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF44009.1 - 2.1e-16 59.2 41.8 0.0011 19.6 1.4 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 OWF44009.1 - 4e-13 49.3 34.2 0.0051 17.2 0.2 7.2 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF44009.1 - 2.3e-05 24.5 32.0 0.18 12.1 0.1 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF44009.1 - 0.00014 21.8 31.2 0.16 12.0 0.3 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF44009.1 - 0.021 15.1 1.6 0.021 15.1 1.6 4.1 3 1 2 5 5 4 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 OWF44009.1 - 0.028 14.2 24.5 0.17 11.7 0.2 5.6 5 0 0 5 5 5 0 C2H2-type zinc-finger domain DUF3449 PF11931.8 OWF44009.1 - 0.032 14.0 1.8 0.28 11.0 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) BolA PF01722.18 OWF44009.1 - 0.88 9.9 6.2 23 5.4 0.0 4.2 3 1 1 4 4 2 0 BolA-like protein zf-C2H2_2 PF12756.7 OWF44009.1 - 1.4 9.3 32.1 4.7 7.6 4.9 5.2 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 OWF44009.1 - 4 7.1 13.5 4.2 7.1 0.6 3.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 OWF44009.1 - 6.9 7.0 24.2 0.59 10.4 5.2 4.9 4 1 1 5 5 5 0 LIM domain AAA PF00004.29 OWF44010.1 - 1.9e-41 141.6 0.0 7.7e-41 139.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF44010.1 - 1.3e-08 34.5 0.1 3.2e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OWF44010.1 - 8.1e-05 22.9 0.0 0.0056 17.0 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 OWF44010.1 - 0.00013 21.9 0.0 0.00063 19.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OWF44010.1 - 0.00051 20.2 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OWF44010.1 - 0.0014 17.8 0.0 0.004 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OWF44010.1 - 0.0019 18.6 0.1 0.031 14.7 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OWF44010.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OWF44010.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OWF44010.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OWF44010.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 OWF44010.1 - 0.019 15.5 0.0 0.054 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 OWF44010.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 OWF44010.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 OWF44010.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OWF44010.1 - 0.09 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 OWF44010.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OWF44010.1 - 0.13 12.0 0.1 0.68 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OWF44010.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OWF44010.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain LPMO_10 PF03067.15 OWF44011.1 - 9e-37 127.6 2.4 9e-37 127.6 2.4 1.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading zf-ANAPC11 PF12861.7 OWF44011.1 - 0.02 14.9 1.4 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_recom PF13408.6 OWF44011.1 - 0.2 12.2 3.4 0.6 10.7 3.4 1.9 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Ion_trans PF00520.31 OWF44012.1 - 2.5e-21 76.1 17.4 3.2e-21 75.7 17.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF44012.1 - 9.6e-13 47.9 9.0 3.5e-12 46.1 9.0 2.0 1 0 0 1 1 1 1 Ion channel DUF979 PF06166.12 OWF44012.1 - 0.007 15.6 1.7 0.011 14.9 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF979) EF-hand_7 PF13499.6 OWF44013.1 - 2.5e-24 85.5 14.7 8.9e-10 38.9 1.1 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF44013.1 - 2.6e-17 61.2 5.6 0.00015 21.4 0.1 6.6 6 0 0 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 OWF44013.1 - 6.6e-17 59.7 23.0 4.9e-05 22.6 0.1 7.4 8 0 0 8 8 8 5 EF hand EF-hand_8 PF13833.6 OWF44013.1 - 6.1e-10 38.8 11.7 0.016 15.0 0.0 5.9 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF44013.1 - 3.8e-06 27.2 18.8 0.0036 17.6 3.5 3.3 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 OWF44013.1 - 0.0088 15.5 0.0 0.0088 15.5 0.0 6.4 8 0 0 8 8 8 1 EF hand EF-hand_10 PF14788.6 OWF44013.1 - 0.0093 15.8 0.6 1.4 8.8 0.0 3.4 2 1 1 3 3 3 1 EF hand EF-hand_4 PF12763.7 OWF44013.1 - 0.48 10.4 5.5 0.48 10.4 0.7 3.0 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Cyclin_C PF02984.19 OWF44014.1 - 1.9e-05 24.8 0.0 1.9e-05 24.8 0.0 2.7 3 1 0 3 3 3 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 OWF44014.1 - 0.0023 17.7 0.0 0.23 11.2 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OWF44014.1 - 0.003 17.9 0.1 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin C-terminal domain PhyH PF05721.13 OWF44015.1 - 1.3e-10 41.9 0.1 4.3e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OWF44015.1 - 0.01 14.7 0.1 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) NHL PF01436.21 OWF44017.1 - 1.9e-16 59.2 8.5 4.6e-05 23.2 0.0 5.3 5 1 0 5 5 5 3 NHL repeat Filamin PF00630.19 OWF44017.1 - 3.9e-13 50.1 1.1 1.1e-12 48.7 0.2 2.2 3 0 0 3 3 2 1 Filamin/ABP280 repeat zf-B_box PF00643.24 OWF44017.1 - 2.3e-07 30.8 2.4 2.3e-07 30.8 2.4 3.7 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 OWF44017.1 - 8.1e-05 22.6 8.2 8.1e-05 22.6 8.2 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF44017.1 - 0.00016 21.9 13.2 0.00016 21.9 13.2 2.7 2 0 0 2 2 2 1 Ring finger domain Invasin_D3 PF09134.10 OWF44017.1 - 0.0005 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Invasin, domain 3 zf-RING_5 PF14634.6 OWF44017.1 - 0.00058 19.8 13.4 0.00058 19.8 13.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain DUF5128 PF17170.4 OWF44017.1 - 0.0033 16.6 3.7 0.17 11.0 0.6 3.2 2 1 1 3 3 3 1 6-bladed beta-propeller zf-C3HC4 PF00097.25 OWF44017.1 - 0.0081 16.0 13.7 0.0081 16.0 13.7 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.12 OWF44017.1 - 0.015 15.3 6.4 0.056 13.5 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ran-binding PF05508.11 OWF44017.1 - 0.037 13.0 2.0 0.067 12.2 2.0 1.4 1 0 0 1 1 1 0 RanGTP-binding protein VCBS PF13517.6 OWF44017.1 - 0.051 14.2 0.7 5.9 7.6 0.1 3.4 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SGL PF08450.12 OWF44017.1 - 0.071 12.7 0.1 35 3.8 0.0 3.8 2 2 2 5 5 5 0 SMP-30/Gluconolactonase/LRE-like region Neurexophilin PF06312.12 OWF44017.1 - 0.13 11.7 0.0 0.13 11.7 0.0 2.5 3 0 0 3 3 2 0 Neurexophilin ING PF12998.7 OWF44017.1 - 0.79 10.3 7.1 1 10.0 5.9 1.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF724 PF05266.14 OWF44017.1 - 3.8 7.3 7.6 2.8 7.7 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) zf-C3HC4_4 PF15227.6 OWF44017.1 - 9 6.6 21.8 0.69 10.1 11.7 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SNF PF00209.18 OWF44018.1 - 2.9e-178 593.8 32.7 3.4e-178 593.6 32.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Pkinase_Tyr PF07714.17 OWF44019.1 - 1e-51 175.7 0.1 1.6e-51 175.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF44019.1 - 1.5e-38 132.7 0.0 2.1e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain YEATS PF03366.16 OWF44020.1 - 4.4e-34 116.3 1.5 9.5e-34 115.2 1.5 1.6 1 0 0 1 1 1 1 YEATS family Yuri_gagarin PF15934.5 OWF44020.1 - 0.0002 21.3 0.5 0.0012 18.8 1.4 1.6 2 0 0 2 2 2 1 Yuri gagarin Arm-DNA-bind_5 PF17293.2 OWF44020.1 - 0.00023 21.6 3.5 0.00031 21.1 1.9 2.1 2 1 0 2 2 2 1 Arm DNA-binding domain V-ATPase_C PF03223.15 OWF44020.1 - 0.0041 16.6 1.5 0.0059 16.1 1.5 1.1 1 0 0 1 1 1 1 V-ATPase subunit C FliD_C PF07195.12 OWF44020.1 - 0.015 14.8 0.8 0.024 14.1 0.8 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FapA PF03961.13 OWF44020.1 - 0.016 13.8 1.7 0.021 13.4 1.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 OWF44020.1 - 0.073 12.2 1.5 0.11 11.6 1.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PKcGMP_CC PF16808.5 OWF44020.1 - 0.18 11.6 5.1 0.34 10.8 5.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 OWF44020.1 - 0.23 11.2 3.7 0.55 10.0 3.7 1.6 1 0 0 1 1 1 0 Septum formation initiator Cyclase PF04199.13 OWF44021.1 - 1.4e-34 119.3 0.1 1.8e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 OWF44022.1 - 3.6e-19 69.3 0.0 5.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase IgGFc_binding PF17517.2 OWF44023.1 - 2e-15 56.8 4.8 2e-15 56.8 4.8 3.3 2 1 1 3 3 3 1 IgGFc binding protein Cornifin PF02389.15 OWF44023.1 - 5.7e-12 46.0 69.2 1.1e-06 28.9 27.4 3.1 1 1 2 3 3 3 3 Cornifin (SPRR) family Lectin_C PF00059.21 OWF44023.1 - 7.6e-08 33.1 0.2 7.6e-08 33.1 0.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain zf-C5HC2 PF02928.16 OWF44023.1 - 0.29 11.6 4.0 0.62 10.5 4.0 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger Lectin_C PF00059.21 OWF44024.1 - 2.4e-35 121.5 16.3 4.1e-20 72.5 3.5 2.7 3 0 0 3 3 3 2 Lectin C-type domain Chordopox_A33R PF05966.12 OWF44024.1 - 0.0048 16.2 0.9 0.13 11.6 0.0 2.7 3 0 0 3 3 3 1 Chordopoxvirus A33R protein Mucin PF01456.17 OWF44024.1 - 0.25 11.4 59.1 0.63 10.0 59.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein LBP_C PF17386.2 OWF44025.1 - 0.00036 20.4 42.6 1.4 8.9 0.5 7.7 6 1 2 8 8 8 6 Lacto-N-biose phosphorylase C-terminal domain DrsE_2 PF13686.6 OWF44025.1 - 2 8.3 4.4 30 4.5 4.2 2.3 1 1 0 1 1 1 0 DsrE/DsrF/DrsH-like family PseudoU_synth_1 PF01416.20 OWF44026.1 - 5.5e-28 97.6 0.0 1.5e-26 93.0 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase QVR PF17064.5 OWF44027.1 - 4.7e-09 36.4 7.2 8.4e-09 35.6 7.2 1.4 1 1 0 1 1 1 1 Sleepless protein RhoGEF PF00621.20 OWF44028.1 - 9.9e-33 113.9 0.3 2.3e-32 112.7 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 OWF44028.1 - 3.1e-12 45.9 0.3 9e-12 44.4 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF44028.1 - 1.9e-10 40.5 0.6 5.9e-10 38.9 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OWF44028.1 - 2.2e-09 36.9 0.0 4.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 OWF44028.1 - 0.00098 19.6 0.4 0.0074 16.8 0.1 2.7 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 OWF44028.1 - 0.0018 18.3 0.0 0.0062 16.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 OWF44028.1 - 0.017 15.0 1.3 0.053 13.3 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain SCIMP PF15050.6 OWF44028.1 - 3.7 8.0 6.1 71 3.9 0.7 4.0 3 0 0 3 3 3 0 SCIMP protein 7tm_1 PF00001.21 OWF44029.1 - 2e-23 83.1 19.7 1.5e-18 67.1 6.0 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF44029.1 - 0.00033 20.5 5.8 0.00033 20.5 5.8 3.1 3 0 0 3 3 3 1 Olfactory receptor Ctr PF04145.15 OWF44029.1 - 0.059 14.0 0.4 0.059 14.0 0.4 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Baculo_PEP_C PF04513.12 OWF44031.1 - 7.8e-05 22.7 15.6 0.0017 18.4 6.7 3.3 1 1 3 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 OWF44031.1 - 9.2e-05 22.3 3.6 3.5 7.5 0.1 5.0 1 1 3 5 5 5 2 CdvA-like coiled-coil domain NPV_P10 PF05531.12 OWF44031.1 - 0.0017 18.7 8.7 3.9 8.0 0.6 5.3 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 OWF44031.1 - 0.0018 18.3 6.7 0.13 12.3 0.1 3.8 1 1 3 4 4 4 3 Protein of unknown function (DUF2730) Lectin_C PF00059.21 OWF44031.1 - 0.002 18.9 0.2 0.0057 17.4 0.1 1.7 2 0 0 2 2 2 1 Lectin C-type domain Phasin PF05597.11 OWF44031.1 - 0.011 15.8 4.0 0.81 9.7 0.2 3.6 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MetOD2 PF18548.1 OWF44031.1 - 0.012 15.6 0.8 14 5.9 0.0 3.7 3 1 1 4 4 4 0 Metanogen output domain 2 DUF4191 PF13829.6 OWF44031.1 - 0.018 14.4 5.7 1.5 8.1 0.2 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4191) DUF2939 PF11159.8 OWF44031.1 - 0.12 12.8 1.4 20 5.7 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2939) SLATT_fungal PF18142.1 OWF44031.1 - 0.64 10.0 9.0 14 5.7 0.0 4.3 2 2 2 5 5 5 0 SMODS and SLOG-associating 2TM effector domain XhlA PF10779.9 OWF44031.1 - 2.4 8.4 5.6 2.8 8.2 0.3 3.3 2 1 1 3 3 3 0 Haemolysin XhlA adh_short PF00106.25 OWF44032.1 - 5.1e-32 110.9 0.0 2.7e-26 92.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF44032.1 - 2.8e-22 79.4 0.0 9.6e-19 67.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF44032.1 - 3.8e-07 30.2 0.0 5.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF44032.1 - 8e-05 22.2 0.0 0.00043 19.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rer1 PF03248.13 OWF44033.1 - 2.5e-77 258.4 7.1 2.9e-77 258.2 7.1 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 OWF44033.1 - 0.036 13.7 1.3 0.036 13.7 1.3 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Halogen_Hydrol PF10112.9 OWF44033.1 - 0.63 10.0 2.0 24 4.9 0.7 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PseudoU_synth_1 PF01416.20 OWF44034.1 - 3.6e-11 43.5 0.1 5.7e-08 33.2 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF4483 PF14825.6 OWF44034.1 - 0.0089 15.8 0.9 0.016 14.9 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) DUF1565 PF07602.11 OWF44034.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) SNF PF00209.18 OWF44035.1 - 5.4e-170 566.5 34.7 4.5e-169 563.5 34.7 1.9 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family HbrB PF08539.11 OWF44035.1 - 0.17 11.9 1.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 HbrB-like Ank_2 PF12796.7 OWF44036.1 - 2.5e-164 534.3 30.2 5.8e-12 46.0 0.0 10.4 1 1 18 19 19 19 18 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF44036.1 - 4.1e-76 250.4 13.8 2.2e-07 31.3 0.0 16.4 15 2 2 17 17 17 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF44036.1 - 4.7e-74 243.5 26.2 3.9e-06 27.0 0.0 17.3 2 1 17 19 19 19 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44036.1 - 4.3e-57 183.4 21.5 0.0029 18.0 0.0 18.2 18 0 0 18 18 18 17 Ankyrin repeat Ank PF00023.30 OWF44036.1 - 3.6e-47 156.8 37.6 0.023 15.2 0.0 18.3 19 0 0 19 19 19 17 Ankyrin repeat Prok_Ub PF14454.6 OWF44036.1 - 3.4e-22 77.9 7.7 46 3.8 0.0 18.0 19 0 0 19 19 19 0 Prokaryotic Ubiquitin DUF494 PF04361.13 OWF44036.1 - 0.00064 19.6 3.7 1.1e+02 2.7 0.0 9.8 15 0 0 15 15 15 0 Protein of unknown function (DUF494) Ank_2 PF12796.7 OWF44037.1 - 1.3e-52 176.3 7.0 2.1e-13 50.6 0.1 4.2 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF44037.1 - 6.7e-22 77.6 1.2 1.7e-05 25.2 0.1 5.8 5 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44037.1 - 4.2e-21 72.8 1.0 0.014 15.8 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OWF44037.1 - 5.9e-19 67.9 2.2 1.1e-05 25.6 0.0 6.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF44037.1 - 8e-19 67.2 1.0 0.015 15.8 0.0 6.1 7 0 0 7 7 7 5 Ankyrin repeat Prok_Ub PF14454.6 OWF44037.1 - 5.5e-09 35.5 0.1 20 4.9 0.0 6.1 6 0 0 6 6 6 0 Prokaryotic Ubiquitin TGT_C1 PF14809.6 OWF44037.1 - 0.0035 17.6 0.0 3e+02 1.8 0.0 5.5 6 0 0 6 6 6 0 C1 domain of tRNA-guanine transglycosylase dimerisation DUF2585 PF10755.9 OWF44037.1 - 0.086 12.6 0.0 25 4.5 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2585) ARL17 PF15840.5 OWF44037.1 - 0.16 12.4 2.0 2.4 8.6 0.0 3.6 4 1 1 5 5 5 0 ADP-ribosylation factor-like protein 17 DUF442 PF04273.13 OWF44037.1 - 0.17 12.0 0.6 24 5.0 0.1 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) SNF PF00209.18 OWF44038.1 - 1.1e-172 575.5 38.0 1.2e-172 575.3 38.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RhodobacterPufX PF11511.8 OWF44038.1 - 6.3 6.5 6.3 18 5.0 1.0 3.5 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Pkinase_C PF00433.24 OWF44039.1 - 0.11 13.2 0.5 0.72 10.6 0.5 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain DUF4612 PF15389.6 OWF44039.1 - 0.25 12.4 2.5 14 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) APG6 PF04111.12 OWF44040.1 - 3.2e-76 255.3 0.1 5.9e-76 254.4 0.1 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OWF44040.1 - 1.3e-34 119.6 29.9 1.3e-34 119.6 29.9 1.6 2 0 0 2 2 1 1 Apg6 coiled-coil region BH3 PF15285.6 OWF44040.1 - 6.1e-10 38.6 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting zf-C4H2 PF10146.9 OWF44040.1 - 0.0007 20.0 1.1 0.0011 19.4 1.1 1.5 1 0 0 1 1 1 1 Zinc finger-containing protein YabA PF06156.13 OWF44040.1 - 0.0017 19.0 7.4 0.0017 19.0 7.4 2.2 3 0 0 3 3 1 1 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OWF44040.1 - 0.0018 18.3 20.7 0.0019 18.2 19.3 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1640 PF07798.11 OWF44040.1 - 0.002 18.2 10.5 0.72 9.9 11.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.22 OWF44040.1 - 0.0023 18.1 15.9 0.0042 17.3 15.5 1.6 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ERM PF00769.19 OWF44040.1 - 0.0031 17.4 20.5 0.0052 16.6 20.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF737 PF05300.11 OWF44040.1 - 0.0046 17.3 6.4 0.0058 17.0 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) Suppressor_APC PF11414.8 OWF44040.1 - 0.005 16.9 11.4 0.005 16.9 11.4 2.2 1 1 1 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein ATG16 PF08614.11 OWF44040.1 - 0.006 16.8 16.8 0.013 15.8 16.8 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) COG2 PF06148.11 OWF44040.1 - 0.0074 16.4 8.8 0.024 14.7 8.5 2.1 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Tektin PF03148.14 OWF44040.1 - 0.0086 14.9 7.3 0.0086 14.9 7.3 2.5 1 1 1 2 2 2 1 Tektin family TACC_C PF05010.14 OWF44040.1 - 0.0099 15.7 15.3 0.02 14.7 15.3 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Atg14 PF10186.9 OWF44040.1 - 0.014 14.5 3.6 0.023 13.8 3.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CALCOCO1 PF07888.11 OWF44040.1 - 0.029 13.2 17.2 0.046 12.6 17.2 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAUS-augmin3 PF14932.6 OWF44040.1 - 0.094 12.3 18.4 0.17 11.4 18.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 OWF44040.1 - 0.1 11.4 17.6 0.21 10.5 17.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein IFT57 PF10498.9 OWF44040.1 - 0.11 11.5 16.3 0.21 10.6 16.3 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 betaPIX_CC PF16523.5 OWF44040.1 - 0.12 12.2 14.2 0.069 13.0 10.7 2.3 1 1 1 2 2 2 0 betaPIX coiled coil Exonuc_VII_L PF02601.15 OWF44040.1 - 0.12 11.9 4.8 0.19 11.3 4.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_10 PF16685.5 OWF44040.1 - 0.13 12.4 0.3 0.58 10.3 0.1 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 V_ATPase_I PF01496.19 OWF44040.1 - 0.15 10.0 7.4 0.2 9.6 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4600 PF15372.6 OWF44040.1 - 0.19 12.1 18.5 18 5.8 8.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Jnk-SapK_ap_N PF09744.9 OWF44040.1 - 0.2 11.9 26.2 0.14 12.4 23.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 OWF44040.1 - 0.21 11.6 7.2 0.34 11.0 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GPS2_interact PF15784.5 OWF44040.1 - 0.22 12.0 11.5 0.27 11.7 10.5 1.7 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain CortBP2 PF09727.9 OWF44040.1 - 0.23 11.4 17.4 0.38 10.6 17.4 1.4 1 0 0 1 1 1 0 Cortactin-binding protein-2 AAA_11 PF13086.6 OWF44040.1 - 0.27 11.0 4.5 0.44 10.3 4.5 1.4 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 OWF44040.1 - 0.29 10.5 8.2 0.53 9.6 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 OWF44040.1 - 0.32 10.2 10.6 0.57 9.4 10.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein FPP PF05911.11 OWF44040.1 - 0.34 9.1 17.1 0.078 11.2 14.0 1.4 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4140 PF13600.6 OWF44040.1 - 0.34 11.4 18.5 2.2 8.8 4.8 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2935 PF11155.8 OWF44040.1 - 0.35 11.2 8.0 0.25 11.7 4.9 2.3 2 1 1 3 3 2 0 Domain of unknown function (DUF2935) FlgN PF05130.12 OWF44040.1 - 0.35 11.4 13.0 0.42 11.1 10.8 2.1 2 0 0 2 2 2 0 FlgN protein GAS PF13851.6 OWF44040.1 - 0.36 10.2 23.4 0.43 9.9 9.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PA26 PF04636.13 OWF44040.1 - 0.37 9.6 8.1 0.57 9.0 8.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Golgin_A5 PF09787.9 OWF44040.1 - 0.54 9.7 17.6 0.9 8.9 17.6 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 BLOC1_2 PF10046.9 OWF44040.1 - 0.56 10.6 11.9 0.88 9.9 10.2 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 OWF44040.1 - 0.62 8.6 16.5 0.37 9.3 9.9 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 OWF44040.1 - 0.67 10.2 22.4 16 5.7 0.0 3.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cwf_Cwc_15 PF04889.12 OWF44040.1 - 0.83 9.3 17.0 1.4 8.6 17.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2968 PF11180.8 OWF44040.1 - 1.2 8.8 16.1 0.43 10.2 12.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Laminin_II PF06009.12 OWF44040.1 - 1.2 9.1 7.5 2.9 7.9 7.5 1.6 1 0 0 1 1 1 0 Laminin Domain II Sin3_corepress PF08295.12 OWF44040.1 - 1.8 8.7 10.3 4.3 7.5 5.4 2.5 1 1 1 2 2 2 0 Sin3 family co-repressor Occludin_ELL PF07303.13 OWF44040.1 - 2.3 9.0 13.1 4.9 7.9 11.7 2.3 1 1 0 1 1 1 0 Occludin homology domain LMBR1 PF04791.16 OWF44040.1 - 3.6 6.4 6.2 5.4 5.8 6.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-H PF05837.12 OWF44040.1 - 4.1 7.9 17.9 2.3 8.7 13.3 2.4 3 0 0 3 3 2 0 Centromere protein H (CENP-H) Prominin PF05478.11 OWF44040.1 - 4.1 5.2 6.4 6.7 4.5 6.4 1.3 1 0 0 1 1 1 0 Prominin Snf7 PF03357.21 OWF44040.1 - 7.3 6.2 21.5 1.6 8.3 16.5 2.1 1 1 1 2 2 2 0 Snf7 THOC7 PF05615.13 OWF44040.1 - 9.9 6.5 22.5 4.3e+02 1.2 22.4 2.6 1 1 0 1 1 1 0 Tho complex subunit 7 UPF0506 PF11703.8 OWF44041.1 - 4.4 7.8 19.4 2.7 8.4 4.5 2.2 2 0 0 2 2 2 0 UPF0506 Aldolase_II PF00596.21 OWF44042.1 - 2.2e-36 125.5 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 7TM_GPCR_Srw PF10324.9 OWF44043.1 - 2.8e-36 125.4 27.6 3.4e-36 125.1 27.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF44043.1 - 2.5e-12 46.7 18.8 2.5e-12 46.7 18.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Carm_PH PF17888.1 OWF44043.1 - 0.078 13.3 0.3 0.26 11.7 0.3 1.9 1 0 0 1 1 1 0 Carmil pleckstrin homology domain DUF2569 PF10754.9 OWF44043.1 - 5.2 7.5 24.9 1 9.8 1.0 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2569) Somatomedin_B PF01033.17 OWF44044.1 - 7.2 7.1 25.1 1.3 9.5 1.5 3.9 1 1 3 4 4 4 0 Somatomedin B domain ApoO PF09769.9 OWF44045.1 - 1.3e-06 28.4 0.1 3.3 7.7 0.1 5.8 1 1 1 2 2 2 1 Apolipoprotein O DUF4751 PF15942.5 OWF44045.1 - 4.7e-06 26.6 0.0 35 4.4 0.0 5.2 1 1 6 8 8 8 2 Domain of unknown function (DUF4751) DUF3584 PF12128.8 OWF44045.1 - 0.088 10.3 28.3 0.21 9.1 6.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) VGLL4 PF15245.6 OWF44045.1 - 0.27 11.3 0.4 29 4.6 0.0 4.0 1 1 2 4 4 4 0 Transcription cofactor vestigial-like protein 4 Grg1 PF11034.8 OWF44045.1 - 0.68 10.2 29.6 2e+02 2.3 0.0 11.9 1 1 14 15 15 15 0 Glucose-repressible protein Grg1 Methyltransf_11 PF08241.12 OWF44047.1 - 2e-15 57.2 0.0 2.9e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44047.1 - 2.7e-15 56.8 0.0 1.3e-14 54.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44047.1 - 1.5e-06 28.8 0.0 3.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF44047.1 - 1.9e-05 24.5 0.0 5.2e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF44047.1 - 0.00024 21.0 0.0 0.00037 20.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 OWF44047.1 - 0.00041 19.5 0.0 0.0066 15.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 OWF44047.1 - 0.0024 17.4 0.0 0.0085 15.6 0.0 1.8 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 OWF44047.1 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 OWF44047.1 - 0.017 14.9 0.0 0.082 12.7 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_33 PF10017.9 OWF44047.1 - 0.039 13.1 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_29 PF03141.16 OWF44047.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 OWF44047.1 - 0.16 11.5 0.0 0.76 9.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 OWF44048.1 - 1.3e-64 218.1 0.0 2e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF44048.1 - 2.1e-30 105.9 0.0 3.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF44048.1 - 3.4e-05 23.3 0.6 0.0024 17.2 0.1 2.3 1 1 1 2 2 2 2 Kinase-like zf-C2H2 PF00096.26 OWF44050.1 - 5.7e-06 26.5 30.1 0.027 14.9 0.1 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF44050.1 - 0.0015 18.8 1.9 0.0015 18.8 1.9 7.7 10 0 0 10 10 10 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF44050.1 - 0.013 16.3 0.2 0.013 16.3 0.2 6.6 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF44050.1 - 0.03 14.6 0.4 0.03 14.6 0.4 4.2 2 1 4 6 6 6 0 C2H2-type zinc ribbon zf-RVT PF13966.6 OWF44050.1 - 0.074 13.8 6.0 0.29 11.9 6.0 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase AT_hook PF02178.19 OWF44050.1 - 0.5 10.4 16.7 0.1 12.5 1.2 2.8 2 0 0 2 2 2 0 AT hook motif zf-C2H2_12 PF18658.1 OWF44050.1 - 1.3 8.6 6.8 0.35 10.5 0.7 3.1 4 0 0 4 4 4 0 Zinc-finger C2H2-type FOXP-CC PF16159.5 OWF44050.1 - 1.5 9.5 9.0 0.15 12.7 0.8 3.5 3 1 0 3 3 3 0 FOXP coiled-coil domain Elf1 PF05129.13 OWF44050.1 - 8.1 6.6 20.7 5.2 7.2 6.1 3.6 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like R3H PF01424.22 OWF44051.1 - 2e-13 50.1 0.0 4.9e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain UPF0564 PF10595.9 OWF44051.1 - 0.13 11.3 20.2 0.57 9.2 5.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0564 Goodbye PF17109.5 OWF44051.1 - 3.7 8.0 5.8 0.52 10.8 0.4 2.2 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain Nexin_C PF08628.12 OWF44051.1 - 7.3 7.2 6.4 0.81 10.3 0.2 2.3 1 1 1 2 2 2 0 Sorting nexin C terminal NDUF_B5 PF09781.9 OWF44052.1 - 1.1e-34 119.6 0.0 1.4e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit zf-C2H2 PF00096.26 OWF44053.1 - 5.7e-23 80.0 82.8 0.01 16.2 1.2 11.8 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF44053.1 - 3.6e-14 52.3 84.0 0.05 14.4 0.7 11.8 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF44053.1 - 0.0037 17.0 0.3 0.0037 17.0 0.3 8.0 9 0 0 9 9 9 2 zinc-finger C2H2-type zf_C2H2_10 PF18414.1 OWF44053.1 - 0.018 14.6 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2H2_6 PF13912.6 OWF44053.1 - 3.1 7.9 56.3 0.057 13.4 0.8 9.6 10 0 0 10 10 10 0 C2H2-type zinc finger RRM_1 PF00076.22 OWF44054.1 - 4.1e-38 129.0 0.0 7.1e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF44054.1 - 2.9e-06 27.3 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OWF44054.1 - 2.1e-05 24.1 0.0 0.014 15.0 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 OWF44054.1 - 0.099 12.3 0.2 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 OWF44054.1 - 0.22 11.6 0.2 11 6.2 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 7TM_GPCR_Srw PF10324.9 OWF44055.1 - 3.7e-43 148.0 11.4 8.2e-43 146.9 11.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF44055.1 - 7.1e-12 45.2 11.0 2.4e-11 43.5 11.0 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44055.1 - 3.1e-08 33.6 18.2 1.1e-07 31.8 18.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PMT_4TMC PF16192.5 OWF44055.1 - 0.062 12.9 10.3 0.041 13.5 0.9 3.2 2 1 1 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase CAP PF00188.26 OWF44056.1 - 9.9e-20 71.6 4.8 1.9e-19 70.7 4.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cation_efflux PF01545.21 OWF44057.1 - 3.9e-29 101.8 6.1 4.8e-29 101.5 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OWF44057.1 - 4.2e-11 42.8 0.0 9.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MARVEL PF01284.23 OWF44057.1 - 0.096 12.7 12.1 0.59 10.2 1.1 3.0 2 1 1 3 3 3 0 Membrane-associating domain PMP22_Claudin PF00822.20 OWF44058.1 - 0.00015 21.7 8.1 0.00059 19.8 8.1 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF44058.1 - 0.00038 20.3 7.5 0.00078 19.3 4.9 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3413 PF11893.8 OWF44058.1 - 0.064 12.4 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) TMIE PF16038.5 OWF44058.1 - 0.066 13.1 2.0 0.15 12.0 2.0 1.5 1 0 0 1 1 1 0 TMIE protein MARVEL PF01284.23 OWF44058.1 - 0.33 11.0 6.6 1.7 8.7 6.7 2.0 1 1 0 1 1 1 0 Membrane-associating domain DuoxA PF10204.9 OWF44058.1 - 2.8 6.9 6.5 0.3 10.1 2.3 1.5 2 0 0 2 2 2 0 Dual oxidase maturation factor Amidohydro_3 PF07969.11 OWF44059.1 - 2.3e-14 53.7 0.0 3.8e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 OWF44059.1 - 3e-13 49.8 0.1 1.1e-07 31.6 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family RRM_1 PF00076.22 OWF44060.1 - 2.7e-23 81.6 6.4 2.4e-10 40.1 0.2 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF44060.1 - 4.4e-08 33.1 0.1 0.0026 17.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OWF44060.1 - 1.1e-06 28.3 0.0 0.013 15.1 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF44060.1 - 0.00013 21.9 3.2 0.043 13.9 0.1 2.9 3 0 0 3 3 3 2 RNA binding motif DUF4523 PF15023.6 OWF44060.1 - 0.019 14.8 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 OWF44060.1 - 0.044 13.7 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4976 PF16347.5 OWF44060.1 - 0.064 13.5 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Nup35_RRM_2 PF14605.6 OWF44060.1 - 0.068 13.2 1.7 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 OWF44060.1 - 0.11 12.5 0.1 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 RL domain RRM_8 PF11835.8 OWF44060.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 RRM-like domain Apt1 PF10351.9 OWF44060.1 - 2.8 6.7 18.2 0.2 10.4 13.3 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.17 OWF44060.1 - 4.3 6.0 9.0 7.4 5.2 9.0 1.4 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 OWF44060.1 - 7.7 4.9 18.9 0.31 9.5 13.1 1.6 2 0 0 2 2 2 0 Macoilin family SPOC PF07744.13 OWF44061.1 - 1.7e-34 118.9 1.7 3e-34 118.1 0.3 2.2 2 0 0 2 2 2 1 SPOC domain GLTP PF08718.11 OWF44062.1 - 8.7e-40 136.4 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Usg PF06233.12 OWF44062.1 - 0.074 13.2 0.0 3.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Usg-like family BORCS6 PF10157.9 OWF44062.1 - 0.09 13.0 0.1 0.66 10.2 0.1 2.2 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Ima1_N PF09779.9 OWF44063.1 - 5.6e-28 98.5 9.3 5.6e-28 98.5 9.3 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain DUF2448 PF10476.9 OWF44063.1 - 0.0016 18.4 0.2 0.0033 17.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) zf-RRPl_C4 PF17026.5 OWF44063.1 - 0.37 10.9 9.3 8.7 6.5 9.3 2.7 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type WD40 PF00400.32 OWF44064.1 - 1.7e-11 44.4 4.5 4.1e-05 24.3 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF44064.1 - 5.2e-06 26.7 0.3 0.13 12.6 0.0 4.4 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 OWF44064.1 - 0.034 13.4 0.0 0.092 12.0 0.0 1.7 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TNFR_c6 PF00020.18 OWF44066.1 - 0.0084 16.5 8.4 0.018 15.5 3.4 3.2 1 1 2 3 3 3 1 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 OWF44066.1 - 0.073 12.8 5.1 0.15 11.8 3.7 2.4 2 1 0 2 2 2 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 OWF44067.1 - 0.025 14.3 8.4 0.21 11.4 4.7 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like DUF4446 PF14584.6 OWF44067.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4577 PF15145.6 OWF44067.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) TNFR_c6 PF00020.18 OWF44067.1 - 1.6 9.2 17.5 0.12 12.8 6.1 3.8 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region HEPN_DZIP3 PF18738.1 OWF44068.1 - 1.9e-30 105.5 0.0 2.9e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN DUF1664 PF07889.12 OWF44068.1 - 2.8e-07 30.6 6.4 0.0032 17.5 0.6 3.1 1 1 1 3 3 3 2 Protein of unknown function (DUF1664) LPP PF04728.13 OWF44068.1 - 1.5e-06 28.5 3.5 0.055 13.9 0.1 3.9 2 1 3 5 5 5 3 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.22 OWF44068.1 - 2.1e-05 24.7 7.8 0.001 19.3 0.4 3.5 3 1 1 4 4 3 2 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 OWF44068.1 - 0.00037 20.5 5.7 0.0034 17.4 1.6 3.1 2 2 0 2 2 2 1 Laminin Domain II WEMBL PF05701.11 OWF44068.1 - 0.00069 18.4 1.3 0.00093 18.0 1.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light NPV_P10 PF05531.12 OWF44068.1 - 0.0007 20.0 8.6 0.11 13.0 5.7 3.6 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 OWF44068.1 - 0.001 19.1 0.3 1.2 9.2 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OWF44068.1 - 0.0026 16.7 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein COG7 PF10191.9 OWF44068.1 - 0.0052 15.1 3.0 0.3 9.3 0.4 2.2 1 1 1 2 2 2 2 Golgi complex component 7 (COG7) NleF_casp_inhib PF16809.5 OWF44068.1 - 0.0095 15.9 1.4 2.7 7.9 0.1 2.7 1 1 1 2 2 2 1 NleF caspase inhibitor Fib_alpha PF08702.10 OWF44068.1 - 0.0098 16.1 0.6 0.8 9.9 0.1 2.4 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family Trans_reg_C PF00486.28 OWF44068.1 - 0.014 15.4 0.1 0.53 10.4 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal DUF2746 PF10874.8 OWF44068.1 - 0.016 15.6 4.5 0.76 10.2 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) Pox_A6 PF04924.12 OWF44068.1 - 0.025 13.5 0.2 0.067 12.1 0.1 1.7 2 0 0 2 2 2 0 Poxvirus A6 protein EzrA PF06160.12 OWF44068.1 - 0.027 12.7 0.0 0.083 11.1 0.0 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF948 PF06103.11 OWF44068.1 - 0.053 13.8 6.1 1.2 9.4 0.5 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Herpes_UL36 PF03586.13 OWF44068.1 - 0.056 12.8 0.4 8.4 5.6 0.0 2.2 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein End3 PF12761.7 OWF44068.1 - 0.074 13.2 0.9 5.9 7.0 0.8 2.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FlaC_arch PF05377.11 OWF44068.1 - 0.12 12.8 3.6 21 5.6 0.8 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.11 OWF44068.1 - 0.15 10.9 0.2 0.27 10.0 0.1 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 OWF44068.1 - 0.18 12.5 0.0 8.7 7.0 0.0 2.6 2 1 1 3 3 2 0 Initiation control protein YabA Type2_restr_D3 PF16902.5 OWF44068.1 - 0.29 11.1 2.2 13 5.8 0.0 3.2 1 1 2 3 3 3 0 Type-2 restriction enzyme D3 domain Prefoldin_2 PF01920.20 OWF44068.1 - 1.4 8.9 6.3 11 6.0 0.7 2.6 1 1 1 2 2 2 0 Prefoldin subunit CsbD PF05532.12 OWF44068.1 - 9.6 6.2 17.0 3.1e+02 1.4 16.7 3.0 1 1 0 1 1 1 0 CsbD-like DUF3523 PF12037.8 OWF44069.1 - 1.1e-89 300.3 21.8 2.3e-89 299.3 21.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 OWF44069.1 - 6.3e-21 75.2 0.0 1.9e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF44069.1 - 3.2e-05 24.2 4.4 0.11 12.7 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 OWF44069.1 - 5.3e-05 23.4 0.1 0.00024 21.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OWF44069.1 - 0.00023 20.6 0.1 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OWF44069.1 - 0.00025 21.4 0.0 0.00025 21.4 0.0 3.3 2 2 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 OWF44069.1 - 0.00048 19.9 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF44069.1 - 0.0025 17.8 0.0 0.012 15.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 OWF44069.1 - 0.0039 17.1 0.2 0.062 13.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 OWF44069.1 - 0.0098 15.9 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OWF44069.1 - 0.01 15.6 0.1 0.031 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OWF44069.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 OWF44069.1 - 0.017 14.8 0.3 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OWF44069.1 - 0.021 15.2 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_lid_3 PF17862.1 OWF44069.1 - 0.022 14.6 0.1 0.07 13.0 0.1 1.8 1 0 0 1 1 1 0 AAA+ lid domain AAA_3 PF07726.11 OWF44069.1 - 0.026 14.4 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OWF44069.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 OWF44069.1 - 0.038 14.5 0.0 0.038 14.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 OWF44069.1 - 0.062 13.2 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 OWF44069.1 - 0.089 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 OWF44069.1 - 0.095 12.5 0.0 0.095 12.5 0.0 3.0 2 1 0 2 2 1 0 AAA domain Zot PF05707.12 OWF44069.1 - 0.18 11.5 3.6 1 9.0 0.1 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Hydin_ADK PF17213.3 OWF44069.1 - 0.25 11.6 0.1 0.25 11.6 0.1 3.8 3 1 0 3 3 2 0 Hydin Adenylate kinase-like domain Ig_Tie2_1 PF10430.9 OWF44069.1 - 1 9.8 4.8 0.26 11.7 0.3 2.3 2 1 1 3 3 3 0 Tie-2 Ig-like domain 1 7tm_1 PF00001.21 OWF44070.1 - 1.9e-56 191.3 15.2 2.3e-56 191.0 15.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44070.1 - 5.7e-10 39.3 16.6 5.7e-10 39.3 16.6 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF44070.1 - 1.2e-09 37.9 19.4 1e-05 25.1 16.5 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF44070.1 - 1.6e-09 37.9 14.6 1.5e-07 31.5 10.6 2.9 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srv PF10323.9 OWF44070.1 - 0.00014 21.4 10.4 0.015 14.7 8.1 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srt PF10321.9 OWF44070.1 - 0.013 14.5 0.1 0.013 14.5 0.1 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt FAM176 PF14851.6 OWF44070.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 FAM176 family PMP22_Claudin PF00822.20 OWF44071.1 - 9.4e-14 51.6 7.6 1.2e-13 51.3 7.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF44071.1 - 7.7e-05 22.5 15.1 0.00094 19.0 14.9 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 OWF44071.1 - 0.041 13.7 3.7 0.068 13.1 3.5 1.6 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Oxidored_q3 PF00499.20 OWF44071.1 - 0.42 10.3 5.8 0.27 10.9 2.0 2.1 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4293 PF14126.6 OWF44071.1 - 0.72 10.1 4.6 0.32 11.2 1.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Amastin PF07344.11 OWF44071.1 - 1 9.2 8.6 1.6 8.6 8.6 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein Tetraspanin PF00335.20 OWF44071.1 - 2.6 7.7 10.3 37 3.9 10.3 2.1 1 1 0 1 1 1 0 Tetraspanin family Scramblase PF03803.15 OWF44073.1 - 1.8e-81 272.6 0.0 2.1e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Scramblase VWA PF00092.28 OWF44074.1 - 2.5e-32 112.5 0.7 3.9e-32 111.9 0.7 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF44074.1 - 8.8e-11 42.4 0.1 2e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF44074.1 - 0.019 14.4 0.2 0.033 13.6 0.2 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Aldedh PF00171.22 OWF44075.1 - 1.5e-180 600.7 0.0 1.7e-180 600.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Scramblase PF03803.15 OWF44076.1 - 1.4e-82 276.2 0.1 1.8e-82 275.9 0.1 1.1 1 0 0 1 1 1 1 Scramblase Methyltransf_11 PF08241.12 OWF44077.1 - 8.9e-16 58.3 0.0 1.7e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44077.1 - 1.5e-15 57.6 0.0 7.7e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44077.1 - 7.1e-07 29.9 0.0 1.7e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF44077.1 - 9.7e-06 25.5 0.0 2.5e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF44077.1 - 7.9e-05 22.5 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 OWF44077.1 - 0.00016 20.9 0.0 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 OWF44077.1 - 0.0023 17.5 0.0 0.0085 15.6 0.0 1.9 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 OWF44077.1 - 0.0028 17.0 0.0 0.0081 15.5 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 OWF44077.1 - 0.022 13.9 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF938 PF06080.12 OWF44077.1 - 0.036 13.8 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_29 PF03141.16 OWF44077.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 OWF44077.1 - 0.13 11.3 0.0 0.4 9.7 0.0 1.7 1 1 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 OWF44077.1 - 0.14 11.7 0.0 0.64 9.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Sod_Fe_C PF02777.18 OWF44078.1 - 0.00022 21.3 0.6 0.00049 20.2 0.2 1.7 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain DUF3137 PF11335.8 OWF44078.1 - 0.0095 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3137) Methyltransf_25 PF13649.6 OWF44079.1 - 4.9e-15 56.0 0.0 2.8e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF44079.1 - 4e-14 53.0 0.0 1.1e-13 51.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44079.1 - 3.7e-06 27.6 0.0 3.6e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF44079.1 - 3.3e-05 23.7 0.0 0.00028 20.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF44079.1 - 4.5e-05 23.3 0.0 6.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44079.1 - 0.0029 17.0 0.0 0.0071 15.7 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OWF44079.1 - 0.015 15.1 0.0 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 Lysine methyltransferase RrnaAD PF00398.20 OWF44079.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OWF44079.1 - 0.11 12.0 0.0 0.42 10.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.7 OWF44080.1 - 5.7e-11 42.9 2.5 0.0057 17.2 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF44080.1 - 4.2e-07 29.8 2.5 0.67 10.7 0.1 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OWF44080.1 - 2e-05 24.8 1.5 2.7 8.4 0.0 5.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF44080.1 - 0.00064 20.2 0.7 0.057 14.0 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) RsgA_GTPase PF03193.16 OWF44080.1 - 0.061 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 OWF44080.1 - 0.076 13.2 0.1 1.1 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF44080.1 - 0.12 12.2 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain NIDO PF06119.14 OWF44081.1 - 5.7e-23 81.7 0.8 1.4e-22 80.5 0.8 1.7 1 0 0 1 1 1 1 Nidogen-like Ninjurin PF04923.12 OWF44082.1 - 1.5e-06 28.1 5.6 2.2e-06 27.5 5.6 1.3 1 0 0 1 1 1 1 Ninjurin Polysacc_synt PF01943.17 OWF44082.1 - 0.014 14.8 2.7 0.019 14.3 2.7 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein E1-E2_ATPase PF00122.20 OWF44082.1 - 0.019 14.5 1.8 0.046 13.2 0.1 1.9 1 1 1 2 2 2 0 E1-E2 ATPase DHHC PF01529.20 OWF44082.1 - 0.14 12.2 2.7 0.13 12.4 0.9 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF5592 PF17332.2 OWF44082.1 - 0.18 12.4 9.2 0.39 11.3 1.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5592) DNA_pol_A_exo1 PF01612.20 OWF44083.1 - 1.2e-46 158.6 0.9 2e-46 157.9 0.9 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OWF44083.1 - 1.2e-20 73.9 1.5 3.1e-20 72.7 0.1 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 OWF44083.1 - 6.1e-12 45.4 0.0 2.1e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 HRDC domain MIIP PF15734.5 OWF44084.1 - 1.3e-47 163.0 18.3 4.3e-46 158.0 18.3 2.1 1 1 0 1 1 1 1 Migration and invasion-inhibitory Glyco_transf_8 PF01501.20 OWF44085.1 - 1.7e-07 31.0 0.1 3.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF5625 PF18539.1 OWF44085.1 - 0.012 15.9 0.3 0.02 15.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5625) SPC25 PF06703.11 OWF44085.1 - 0.26 11.1 5.0 0.39 10.5 3.4 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Fe_hyd_SSU PF02256.17 OWF44085.1 - 0.26 11.4 2.3 32 4.7 0.1 3.1 2 1 1 3 3 3 0 Iron hydrogenase small subunit GFO_IDH_MocA PF01408.22 OWF44086.1 - 1e-18 68.3 0.0 1.1e-17 64.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OWF44086.1 - 0.13 12.3 0.1 2.9 7.9 0.1 2.5 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 OWF44086.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SNF PF00209.18 OWF44087.1 - 1.9e-89 300.8 17.0 2.5e-89 300.4 17.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF44088.1 - 1.1e-09 37.6 1.2 1.3e-09 37.4 1.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family zf-3CxxC PF13695.6 OWF44089.1 - 3e-27 95.0 0.9 4.9e-27 94.3 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 OWF44089.1 - 0.00064 20.4 5.5 3.8 8.3 0.1 3.4 3 0 0 3 3 3 2 Zinc-binding domain Laminin_EGF PF00053.24 OWF44089.1 - 0.34 11.1 0.2 0.34 11.1 0.2 2.9 3 0 0 3 3 3 0 Laminin EGF domain Tnp_zf-ribbon_2 PF13842.6 OWF44089.1 - 0.44 11.4 10.5 1 10.2 1.0 2.9 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Ephrin_rec_like PF07699.13 OWF44089.1 - 2.6 7.9 7.3 3.4 7.5 0.3 3.1 3 0 0 3 3 3 0 Putative ephrin-receptor like TNFR_c6 PF00020.18 OWF44089.1 - 8.7 6.8 8.9 8.1 6.9 0.1 3.2 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region PMP22_Claudin PF00822.20 OWF44090.1 - 2e-13 50.5 7.2 3.3e-13 49.9 7.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF44090.1 - 0.0013 18.6 11.5 0.01 15.6 11.5 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 OWF44090.1 - 0.0041 17.0 7.4 0.0069 16.2 7.4 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3511 PF12023.8 OWF44090.1 - 0.019 14.8 0.7 0.04 13.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) Ferric_reduct PF01794.19 OWF44090.1 - 0.21 11.7 3.4 0.6 10.2 0.0 2.6 2 1 0 2 2 2 0 Ferric reductase like transmembrane component zf-C2H2 PF00096.26 OWF44091.1 - 6e-13 48.5 38.5 0.00034 20.9 5.0 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF44091.1 - 2.3e-12 46.7 30.1 5.2e-07 29.8 0.6 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF44091.1 - 4.4e-08 33.3 33.8 0.051 14.4 1.8 5.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF44091.1 - 0.035 14.4 0.5 0.035 14.4 0.5 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OWF44091.1 - 0.65 10.3 21.5 0.61 10.4 2.6 3.9 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-met PF12874.7 OWF44091.1 - 0.92 10.0 29.3 0.066 13.6 2.2 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Sprouty PF05210.13 OWF44091.1 - 2.3 8.7 8.9 2.9 8.3 5.2 2.3 2 0 0 2 2 2 0 Sprouty protein (Spry) zf-C2H2_3rep PF18868.1 OWF44091.1 - 3.7 8.2 14.1 1.7 9.3 1.9 3.4 2 2 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zinc-ribbons_6 PF07191.12 OWF44091.1 - 5.4 7.1 11.8 9.5 6.3 3.9 2.9 1 1 1 2 2 2 0 zinc-ribbons Pro_isomerase PF00160.21 OWF44092.1 - 4.4e-46 157.0 0.1 4.9e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Guanylate_cyc PF00211.20 OWF44093.1 - 4.2e-31 108.0 0.1 3.3e-25 88.8 0.0 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 OWF44093.1 - 5e-24 86.0 0.0 7.5e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 OWF44093.1 - 2.3e-05 24.0 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Heme NO binding associated NIT PF08376.10 OWF44095.1 - 4.9e-26 92.6 0.0 7.3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing Guanylate_cyc PF00211.20 OWF44095.1 - 7.8e-24 84.3 3.3 1.2e-18 67.4 0.6 2.8 2 1 1 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OWF44095.1 - 2.7e-07 30.3 0.2 8.5e-07 28.6 0.2 1.9 1 0 0 1 1 1 1 Heme NO binding associated 2-Hacid_dh_C PF02826.19 OWF44096.1 - 9.4e-56 188.0 0.0 1.3e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF44096.1 - 6.2e-32 110.1 0.0 7e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 OWF44096.1 - 4.1e-05 23.7 0.5 9.1e-05 22.6 0.5 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 OWF44096.1 - 0.0064 16.7 0.0 0.014 15.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OWF44096.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OWF44096.1 - 0.048 14.2 1.0 0.35 11.5 1.0 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OWF44097.1 - 2.4e-36 124.7 0.0 3.7e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF44097.1 - 2.6e-16 59.5 0.0 2.7e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 OWF44097.1 - 2.6e-05 24.4 0.0 6.6e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 OWF44097.1 - 9.1e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OWF44097.1 - 0.0006 20.3 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OWF44097.1 - 0.0012 19.1 0.0 0.003 17.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OWF44097.1 - 0.11 12.5 0.0 0.4 10.8 0.0 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 OWF44097.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family 7tm_1 PF00001.21 OWF44098.1 - 4.6e-16 58.9 10.8 5.6e-16 58.6 10.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Chordopox_A13L PF05961.11 OWF44098.1 - 3.7 7.9 10.3 0.45 10.8 0.8 3.2 3 0 0 3 3 3 0 Chordopoxvirus A13L protein COX2_TM PF02790.15 OWF44098.1 - 6.7 6.9 7.3 3.7 7.8 0.6 2.9 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4834 PF16118.5 OWF44098.1 - 9.2 7.3 7.1 2.9 8.9 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Jiraiya PF15038.6 OWF44099.1 - 0.089 12.2 4.6 0.77 9.2 0.5 2.5 2 0 0 2 2 2 0 Jiraiya DUF1196 PF06709.11 OWF44099.1 - 0.11 12.7 0.1 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1196) DUF4234 PF14018.6 OWF44099.1 - 2 8.6 7.8 0.77 9.9 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2985 PF11204.8 OWF44099.1 - 3.7 7.8 6.5 0.32 11.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Papilloma_E5A PF05776.12 OWF44099.1 - 6.5 7.2 11.8 25 5.3 0.4 2.5 2 0 0 2 2 2 0 Papillomavirus E5A protein HA2 PF04408.23 OWF44100.1 - 1.1e-18 67.4 0.1 6.9e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OWF44100.1 - 8.4e-18 64.5 0.1 1.7e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OWF44100.1 - 7.5e-16 58.5 0.1 2.2e-15 57.0 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF44100.1 - 9.6e-10 38.5 0.0 2.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF44100.1 - 0.00066 20.0 1.5 0.0023 18.2 0.2 2.6 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OWF44100.1 - 0.0021 18.4 0.0 0.0083 16.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain T2SSE PF00437.20 OWF44100.1 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 OWF44100.1 - 0.023 14.6 0.0 0.082 12.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain Myosin_head PF00063.21 OWF44100.1 - 0.058 11.6 0.2 0.12 10.6 0.0 1.5 2 0 0 2 2 2 0 Myosin head (motor domain) AAA_14 PF13173.6 OWF44100.1 - 0.072 13.1 0.1 2.3 8.3 0.1 2.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF44100.1 - 0.091 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NBD94 PF16830.5 OWF44100.1 - 0.094 13.1 2.6 0.13 12.6 0.2 2.4 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH ATPase PF06745.13 OWF44100.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 OWF44100.1 - 0.51 10.8 6.0 1.5 9.2 0.8 3.0 3 1 1 4 4 3 0 AAA domain DUF3391 PF11871.8 OWF44101.1 - 0.044 14.3 0.7 0.06 13.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Nop14 PF04147.12 OWF44101.1 - 0.58 8.3 5.8 0.55 8.4 5.8 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OWF44101.1 - 1.1 7.2 12.8 1.3 7.1 12.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 OWF44101.1 - 1.9 7.0 4.2 2.1 6.8 4.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cadherin PF00028.17 OWF44102.1 - 2e-07 31.4 0.0 0.0073 16.7 0.0 2.7 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 OWF44102.1 - 4.4e-06 26.9 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_C_2 PF16492.5 OWF44102.1 - 0.0048 17.6 0.0 0.029 15.1 0.0 2.3 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Amnionless PF14828.6 OWF44102.1 - 0.021 13.6 0.0 0.049 12.5 0.0 1.6 2 0 0 2 2 2 0 Amnionless BNIP2 PF12496.8 OWF44102.1 - 1.4 9.3 10.9 0.077 13.4 1.7 2.8 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 BIR PF00653.21 OWF44104.1 - 4.3e-13 49.7 7.5 1.2e-11 45.1 0.2 2.8 1 1 1 2 2 2 2 Inhibitor of Apoptosis domain SKG6 PF08693.10 OWF44104.1 - 0.00045 19.6 0.3 0.00084 18.7 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 OWF44104.1 - 0.00067 19.9 1.4 0.0013 18.9 0.2 2.2 2 0 0 2 2 2 1 Glycophorin A TMEM154 PF15102.6 OWF44104.1 - 0.0079 16.1 0.3 0.0079 16.1 0.3 2.1 2 0 0 2 2 2 1 TMEM154 protein family DUF2207 PF09972.9 OWF44104.1 - 0.016 14.0 0.0 0.032 13.0 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Mid2 PF04478.12 OWF44104.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3169 PF11368.8 OWF44104.1 - 0.026 14.1 0.0 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Ly49 PF08391.10 OWF44104.1 - 0.04 14.3 0.1 0.04 14.3 0.1 2.3 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region VASt PF16016.5 OWF44104.1 - 0.043 14.2 0.9 0.099 13.0 0.9 1.6 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain SIT PF15330.6 OWF44104.1 - 0.065 13.7 0.0 0.25 11.8 0.0 2.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Sigma_reg_N PF13800.6 OWF44104.1 - 0.11 12.8 2.9 1.4 9.3 0.7 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Claudin_2 PF13903.6 OWF44104.1 - 0.25 11.1 2.1 0.19 11.4 0.2 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3377 PF11857.8 OWF44104.1 - 0.44 10.5 5.5 0.33 10.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) DUF1180 PF06679.12 OWF44104.1 - 0.71 10.3 3.1 0.46 10.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 OWF44104.1 - 0.88 10.5 0.0 0.88 10.5 0.0 2.3 3 0 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain Integrin_beta PF00362.18 OWF44106.1 - 4.1e-81 272.3 0.0 6e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 OWF44106.1 - 3e-13 49.2 0.1 5.7e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain I-EGF_1 PF18372.1 OWF44106.1 - 4.3e-09 36.3 11.4 4.3e-09 36.3 11.4 6.4 6 1 0 6 6 6 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 OWF44106.1 - 0.00014 22.2 17.4 0.00014 22.2 17.4 7.8 8 1 1 9 9 9 4 EGF-like domain SCRG1 PF15224.6 OWF44107.1 - 3.5 7.8 25.2 1.2e+02 2.8 6.4 4.6 1 1 2 3 3 3 0 Scrapie-responsive protein 1 Integrin_beta PF00362.18 OWF44108.1 - 2.7e-107 358.0 0.1 5.5e-107 357.0 0.0 1.6 2 0 0 2 2 2 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 OWF44108.1 - 6.4e-22 77.0 0.4 1.1e-21 76.2 0.4 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 OWF44108.1 - 6.1e-15 55.5 11.8 6.1e-15 55.5 11.8 5.0 3 1 1 5 5 5 1 Integrin beta tail domain I-EGF_1 PF18372.1 OWF44108.1 - 8.9e-09 35.3 5.4 8.9e-09 35.3 5.4 7.1 8 0 0 8 8 8 3 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 OWF44108.1 - 3.3e-06 27.3 108.1 0.00012 22.4 9.9 7.3 5 2 1 6 6 6 4 EGF-like domain DUF5305 PF17231.2 OWF44108.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Polyhedrin PF00738.18 OWF44108.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin TRP PF06011.12 OWF44108.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel HECT_2 PF09814.9 OWF44109.1 - 5.8e-37 127.4 1.7 6.8e-37 127.2 1.7 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding CoaE PF01121.20 OWF44110.1 - 2.5e-45 154.3 0.0 7.5e-45 152.8 0.0 1.8 1 0 0 1 1 1 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 OWF44110.1 - 1.6e-08 34.9 0.5 3.9e-07 30.4 0.1 2.9 2 1 0 2 2 2 1 Cytidylyltransferase-like YpjP PF14005.6 OWF44110.1 - 0.094 12.8 0.5 1 9.4 0.1 2.5 3 0 0 3 3 3 0 YpjP-like protein FAD_syn PF06574.12 OWF44110.1 - 0.15 12.0 0.1 2.9 7.7 0.0 2.6 3 0 0 3 3 3 0 FAD synthetase Pkinase PF00069.25 OWF44111.1 - 3e-71 239.9 0.0 4.4e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF44111.1 - 2.9e-33 115.2 0.0 4.7e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF44111.1 - 0.0024 17.3 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Striatin PF08232.12 OWF44111.1 - 1.5 9.4 14.3 7 7.2 0.1 2.4 2 0 0 2 2 2 0 Striatin family CDC45 PF02724.14 OWF44111.1 - 3.2 5.9 17.2 4.4 5.5 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FANCI_S1 PF14675.6 OWF44112.1 - 6.4e-07 29.2 16.0 12 5.3 0.4 8.3 1 1 11 12 12 12 11 FANCI solenoid 1 Peptidase_M19 PF01244.21 OWF44113.1 - 1.3e-106 356.4 0.0 1.7e-106 356.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF4848 PF16140.5 OWF44113.1 - 0.012 15.2 0.4 0.024 14.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) DUF600 PF04634.12 OWF44114.1 - 0.13 12.3 7.9 1.4e+02 2.5 0.1 6.4 2 2 8 10 10 10 0 Protein of unknown function, DUF600 DUF5004 PF16395.5 OWF44114.1 - 0.69 9.9 6.4 40 4.2 0.1 5.2 1 1 5 7 7 7 0 Domain of unknown function (DUF5004) DUF3846 PF12957.7 OWF44114.1 - 0.74 10.2 9.8 13 6.2 0.0 5.4 2 1 2 6 6 6 0 Domain of unknown function (DUF3846) ThrE_2 PF12821.7 OWF44114.1 - 2.3 8.4 8.9 57 3.9 0.1 5.3 4 2 1 5 5 5 0 Threonine/Serine exporter, ThrE ATP-gua_Ptrans PF00217.19 OWF44115.1 - 0.0072 15.8 2.2 3.1 7.2 0.1 3.3 1 1 2 3 3 3 2 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF4099 PF13351.6 OWF44115.1 - 0.039 14.2 0.1 11 6.3 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4099) DUF600 PF04634.12 OWF44115.1 - 0.17 12.0 1.2 43 4.1 0.1 3.3 1 1 2 4 4 4 0 Protein of unknown function, DUF600 DUF2208 PF09973.9 OWF44115.1 - 0.26 10.9 1.4 5.4 6.6 0.3 3.0 1 1 4 5 5 5 0 Predicted membrane protein (DUF2208) Ribosomal_L21p PF00829.21 OWF44118.1 - 0.026 14.7 0.3 0.052 13.8 0.3 1.4 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein POX PF07526.11 OWF44119.1 - 1.1 9.8 5.0 0.54 10.8 0.2 2.3 2 1 0 2 2 2 0 Associated with HOX PC4 PF02229.16 OWF44120.1 - 6.3e-08 32.1 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Fibrinogen_C PF00147.18 OWF44121.1 - 5.5e-49 166.9 8.2 6.8e-49 166.6 8.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Aldo_ket_red PF00248.21 OWF44122.1 - 3.2e-47 161.1 0.0 5.3e-45 153.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF5615 PF18480.1 OWF44122.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Aldo_ket_red PF00248.21 OWF44123.1 - 1.1e-48 165.9 0.0 2.2e-46 158.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF5615 PF18480.1 OWF44123.1 - 0.12 12.1 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Beach PF02138.18 OWF44124.1 - 4.1e-122 406.9 0.1 7.3e-122 406.0 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4800 PF16057.5 OWF44124.1 - 1.1e-103 345.9 4.0 2e-103 345.1 4.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF4704 PF15787.5 OWF44124.1 - 1.3e-32 113.2 1.3 1.3e-32 113.2 1.3 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 OWF44124.1 - 7.5e-22 77.3 0.3 3.1e-21 75.4 0.3 2.2 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OWF44124.1 - 1.6e-09 38.2 4.7 0.0018 19.1 0.6 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 OWF44124.1 - 1e-05 25.7 0.1 2.9e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Herpes_Helicase PF02689.14 OWF44124.1 - 0.0082 14.1 0.1 0.37 8.7 0.1 2.2 2 0 0 2 2 2 2 Helicase AMP-binding PF00501.28 OWF44125.1 - 5.1e-66 223.0 0.0 6.2e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF44125.1 - 0.00049 21.0 0.1 0.0013 19.7 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SH3_2 PF07653.17 OWF44125.1 - 0.11 12.2 0.1 0.37 10.5 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain Rax2 PF12768.7 OWF44126.1 - 0.013 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Guanylate_kin PF00625.21 OWF44127.1 - 8.1e-40 136.4 0.2 8.6e-39 133.1 0.2 2.2 1 1 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 OWF44127.1 - 5.6e-15 55.5 0.3 9.9e-15 54.7 0.3 1.4 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 OWF44127.1 - 1.6e-08 34.1 0.0 3.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF44127.1 - 2.1e-07 30.4 0.1 6.9e-07 28.8 0.1 1.9 1 1 0 1 1 1 1 SH3 domain L27 PF02828.16 OWF44127.1 - 4.6e-07 29.5 1.5 3.8e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 L27 domain SH3_9 PF14604.6 OWF44127.1 - 2.2e-06 27.4 0.0 5.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 OWF44127.1 - 2.7e-05 23.9 0.0 8.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 OWF44127.1 - 0.00012 22.3 0.0 0.00036 20.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Sulfotransfer_1 PF00685.27 OWF44128.1 - 1.5e-46 159.1 2.0 3.5e-45 154.6 2.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF44128.1 - 1.5e-05 25.5 0.0 4.5e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family R3H PF01424.22 OWF44128.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 R3H domain DUF1609 PF07753.11 OWF44128.1 - 0.02 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Nup54 PF13874.6 OWF44128.1 - 0.03 14.4 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Big_1 PF02369.16 OWF44129.1 - 0.12 12.4 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Galactosyl_T PF01762.21 OWF44131.1 - 3.4e-40 137.9 0.1 4.6e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Ecotin PF03974.13 OWF44133.1 - 0.043 13.8 0.3 2.2 8.3 0.0 2.8 1 1 2 3 3 3 0 Ecotin DUF3203 PF11462.8 OWF44133.1 - 0.59 10.4 13.5 18 5.6 0.5 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3203) potato_inhibit PF00280.18 OWF44133.1 - 0.89 10.3 7.3 24 5.7 0.5 3.5 1 1 3 4 4 4 0 Potato inhibitor I family SWI2_SNF2 PF18766.1 OWF44133.1 - 4.4 6.9 5.4 11 5.6 0.0 3.3 1 1 3 4 4 4 0 SWI2/SNF2 ATPase Telomere_reg-2 PF10193.9 OWF44134.1 - 9.4e-12 45.4 0.0 0.85 10.1 0.0 7.7 4 2 5 9 9 9 7 Telomere length regulation protein DUF4199 PF13858.6 OWF44135.1 - 0.09 13.2 0.0 11 6.4 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF4199) CO_dh PF02552.16 OWF44135.1 - 1.1 9.0 3.3 6.9 6.4 0.1 3.4 4 1 0 4 4 4 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF2894 PF11445.8 OWF44135.1 - 1.5 9.2 6.7 26 5.2 5.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2894) DUF983 PF06170.12 OWF44135.1 - 9.2 6.8 13.5 13 6.2 0.3 5.5 2 1 4 7 7 7 0 Protein of unknown function (DUF983) Ig_3 PF13927.6 OWF44136.1 - 1.1e-23 83.6 3.9 1.8e-13 50.9 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 OWF44136.1 - 5.3e-18 64.9 0.0 1.2e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF44136.1 - 7.5e-15 55.0 5.6 1.5e-06 28.4 0.1 3.4 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 OWF44136.1 - 2.7e-09 37.1 4.3 0.00064 19.8 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Alpha_GJ PF03229.13 OWF44136.1 - 3.1 8.4 14.9 1.5 9.4 8.2 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Mucin PF01456.17 OWF44136.1 - 8.4 6.4 34.4 5.1 7.1 26.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C2H2 PF00096.26 OWF44137.1 - 0.00024 21.4 2.6 0.00028 21.2 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf_UBZ PF18439.1 OWF44137.1 - 0.05 13.2 0.7 0.11 12.1 0.7 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 OWF44137.1 - 0.051 14.4 1.9 0.12 13.3 1.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF44137.1 - 0.74 10.4 4.6 1.5 9.4 4.6 1.5 1 0 0 1 1 1 0 Zinc-finger double domain ApoLp-III PF07464.11 OWF44138.1 - 1.1e-05 25.6 0.3 0.0002 21.5 0.1 2.7 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 OWF44138.1 - 1.1e-05 25.8 4.7 0.077 13.5 0.2 3.5 2 1 1 3 3 3 2 YtxH-like protein EF-hand_5 PF13202.6 OWF44138.1 - 9.8e-05 21.7 1.0 0.00043 19.6 0.1 2.5 2 0 0 2 2 2 1 EF hand Baculo_PEP_C PF04513.12 OWF44138.1 - 0.00011 22.2 0.8 0.00028 21.0 0.8 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_1 PF00036.32 OWF44138.1 - 0.00031 20.1 8.1 0.0007 19.0 0.1 3.3 3 0 0 3 3 3 1 EF hand SF-assemblin PF06705.11 OWF44138.1 - 0.0008 18.8 0.3 0.0027 17.1 0.1 1.8 1 1 0 2 2 2 1 SF-assemblin/beta giardin Apolipoprotein PF01442.18 OWF44138.1 - 0.0052 16.7 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain EspB PF05802.11 OWF44138.1 - 0.0056 16.7 10.4 0.018 15.0 10.3 1.9 1 1 0 1 1 1 1 Enterobacterial EspB protein EF-hand_6 PF13405.6 OWF44138.1 - 0.0057 16.5 7.2 0.0094 15.8 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain Chlorosome_CsmC PF11098.8 OWF44138.1 - 0.0059 16.6 26.5 0.075 13.0 13.9 2.5 1 1 2 3 3 3 3 Chlorosome envelope protein C Apt1 PF10351.9 OWF44138.1 - 0.01 14.8 18.2 0.015 14.2 18.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Senescence PF06911.12 OWF44138.1 - 0.015 15.7 6.4 0.045 14.1 5.6 2.2 1 1 1 2 2 2 0 Senescence-associated protein Macoilin PF09726.9 OWF44138.1 - 0.024 13.2 8.1 0.035 12.7 8.1 1.2 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 OWF44138.1 - 0.032 12.2 0.0 0.045 11.7 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF883 PF05957.13 OWF44138.1 - 0.036 14.7 0.1 0.26 11.9 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Collagen_mid PF15984.5 OWF44138.1 - 0.051 13.3 9.4 0.17 11.6 9.4 1.8 1 1 0 1 1 1 0 Bacterial collagen, middle region DUF948 PF06103.11 OWF44138.1 - 0.12 12.6 12.8 7.2 6.9 0.6 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Eclosion PF04736.12 OWF44138.1 - 0.17 11.6 0.3 0.31 10.8 0.3 1.3 1 0 0 1 1 1 0 Eclosion hormone Perilipin PF03036.16 OWF44138.1 - 0.83 8.6 4.9 2.9 6.8 4.9 1.8 1 1 0 1 1 1 0 Perilipin family Peptidase_S64 PF08192.11 OWF44138.1 - 1.8 6.9 12.2 2.5 6.5 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Tape_meas_lam_C PF09718.10 OWF44138.1 - 2.8 8.1 7.7 19 5.5 1.1 3.5 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3852 PF12963.7 OWF44138.1 - 3.5 8.0 4.3 3.4 8.0 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Menin PF05053.13 OWF44138.1 - 4 5.7 11.3 5.9 5.1 11.3 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 OWF44138.1 - 5.2 5.7 13.9 8.4 5.0 13.9 1.2 1 0 0 1 1 1 0 Presenilin TSP_1 PF00090.19 OWF44139.1 - 9e-15 54.6 32.3 7.6e-14 51.7 9.7 3.2 3 0 0 3 3 3 2 Thrombospondin type 1 domain CTD PF12815.7 OWF44140.1 - 2.4e-09 37.6 7.8 3.9e-05 24.1 0.6 2.5 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4988 PF16378.5 OWF44140.1 - 0.016 14.9 1.3 0.36 10.5 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function ComGF PF15980.5 OWF44140.1 - 0.087 13.2 0.7 18 5.8 0.2 3.1 1 1 1 2 2 2 0 Putative Competence protein ComGF DUF3797 PF12677.7 OWF44140.1 - 0.13 12.1 18.8 11 6.0 0.4 6.6 1 1 6 7 7 7 0 Domain of unknown function (DUF3797) TSP_1 PF00090.19 OWF44141.1 - 5.4e-13 48.9 37.7 9.4e-07 29.0 9.8 5.1 5 1 0 5 5 5 3 Thrombospondin type 1 domain CBM_6 PF03422.15 OWF44141.1 - 0.14 12.5 0.6 0.49 10.7 0.0 2.1 3 0 0 3 3 3 0 Carbohydrate binding module (family 6) TSP_1 PF00090.19 OWF44142.1 - 2e-06 27.9 6.6 5e-06 26.6 6.6 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain TSP_1 PF00090.19 OWF44143.1 - 6.8e-20 71.0 74.8 4.2e-09 36.5 7.7 6.6 6 2 0 6 6 6 4 Thrombospondin type 1 domain SH3_4 PF06347.13 OWF44143.1 - 0.01 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_3 PF08239.11 OWF44143.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain TSP_1 PF00090.19 OWF44144.1 - 0.00021 21.4 11.5 0.00021 21.4 11.5 2.5 2 1 0 2 2 2 1 Thrombospondin type 1 domain SH3_3 PF08239.11 OWF44144.1 - 0.0003 21.0 0.1 0.00064 20.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 OWF44144.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain MAPEG PF01124.18 OWF44145.1 - 2.1e-09 37.3 0.4 2.1e-09 37.3 0.4 1.5 2 0 0 2 2 2 1 MAPEG family MAPEG PF01124.18 OWF44146.1 - 7e-11 42.1 0.5 7e-11 42.1 0.5 1.4 2 0 0 2 2 2 1 MAPEG family IPTL-CTERM PF18203.1 OWF44146.1 - 0.33 10.9 3.5 0.71 9.8 3.5 1.5 1 0 0 1 1 1 0 IPTL-CTERM motif TcpE PF12648.7 OWF44146.1 - 0.58 10.7 6.5 0.45 11.1 1.0 2.2 2 0 0 2 2 2 0 TcpE family WD40 PF00400.32 OWF44147.1 - 3.5e-44 147.9 4.5 9.5e-10 38.9 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF44147.1 - 1.8e-10 41.0 0.0 1.4e-05 25.3 0.0 3.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF44147.1 - 5.4e-06 25.3 0.0 1.4 7.4 0.0 4.5 3 1 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF44147.1 - 6.9e-05 22.3 0.0 0.015 14.6 0.1 3.0 1 1 1 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 OWF44147.1 - 0.00072 20.0 0.2 39 4.9 0.0 5.2 6 0 0 6 6 6 0 PQQ-like domain HARP PF07443.13 OWF44147.1 - 0.15 11.7 0.0 89 2.8 0.0 3.4 3 0 0 3 3 3 0 HepA-related protein (HARP) fn3 PF00041.21 OWF44148.1 - 0.0034 17.7 0.0 0.01 16.1 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain Ig_3 PF13927.6 OWF44148.1 - 0.019 15.5 0.1 0.76 10.4 0.0 3.0 2 2 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 OWF44148.1 - 0.068 13.2 0.0 0.6 10.2 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin I-set domain Nefa_Nip30_N PF10187.9 OWF44148.1 - 0.14 12.5 0.7 0.24 11.7 0.7 1.3 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF5320 PF17253.2 OWF44149.1 - 2.6 9.2 17.6 3.6 8.7 17.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) NHL PF01436.21 OWF44150.1 - 5.5e-08 32.5 5.8 0.016 15.2 0.0 5.5 6 0 0 6 6 5 2 NHL repeat zf-C3HC4 PF00097.25 OWF44150.1 - 6.4e-08 32.3 14.5 6.4e-08 32.3 14.5 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF44150.1 - 1.1e-07 31.7 11.1 1.1e-07 31.7 11.1 2.8 2 1 1 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 OWF44150.1 - 1e-06 28.7 21.6 3.5e-06 27.1 8.7 3.7 3 1 0 3 3 2 2 B-box zinc finger zf-C3HC4_4 PF15227.6 OWF44150.1 - 1.1e-05 25.5 15.6 1.1e-05 25.5 15.6 3.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF44150.1 - 1.2e-05 25.1 10.6 1.2e-05 25.1 10.6 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF44150.1 - 5.3e-05 23.5 14.1 5.3e-05 23.5 14.1 3.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF44150.1 - 6e-05 22.9 13.5 6e-05 22.9 13.5 3.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF44150.1 - 0.00031 20.5 15.0 0.00031 20.5 15.0 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44150.1 - 0.00092 19.0 12.5 0.00092 19.0 12.5 3.6 3 1 1 4 4 2 2 Prokaryotic RING finger family 4 SGL PF08450.12 OWF44150.1 - 0.0018 17.9 0.3 0.018 14.6 0.1 2.3 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region RRF PF01765.19 OWF44150.1 - 0.0051 16.8 0.2 0.012 15.6 0.2 1.6 1 0 0 1 1 1 1 Ribosome recycling factor Str_synth PF03088.16 OWF44150.1 - 0.0067 16.5 0.0 0.042 14.0 0.0 2.3 1 1 1 2 2 2 1 Strictosidine synthase DUF4637 PF15470.6 OWF44150.1 - 0.0077 16.0 0.4 0.0077 16.0 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4637) Arylesterase PF01731.20 OWF44150.1 - 0.009 16.2 0.1 0.1 12.8 0.0 2.3 2 0 0 2 2 2 1 Arylesterase Histidinol_dh PF00815.20 OWF44150.1 - 0.9 8.5 2.4 2 7.4 1.8 1.8 1 1 1 2 2 2 0 Histidinol dehydrogenase PDZ PF00595.24 OWF44151.1 - 7.4e-39 132.0 1.7 5.2e-13 49.2 0.1 3.5 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 OWF44151.1 - 7.2e-37 125.7 0.0 1.7e-36 124.5 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain PDZ_6 PF17820.1 OWF44151.1 - 5.3e-22 77.4 1.6 1.6e-07 31.0 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OWF44151.1 - 1.3e-13 51.1 3.7 0.0019 18.5 0.2 3.6 2 1 1 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 OWF44151.1 - 6.5e-12 45.5 0.0 1.6e-10 41.0 0.0 2.5 1 1 1 2 2 2 1 Guanylate kinase SH3_2 PF07653.17 OWF44151.1 - 4.4e-08 32.7 0.1 1.1e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain CARD PF00619.21 OWF44151.1 - 6.2e-08 32.6 0.1 1.5e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Caspase recruitment domain SH3_1 PF00018.28 OWF44151.1 - 0.0026 17.3 0.1 0.0092 15.6 0.1 2.1 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF44151.1 - 0.059 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain KOG2701 PF09762.9 OWF44151.1 - 1.9 8.7 12.0 0.32 11.2 0.2 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein (DUF2037) COMM_domain PF07258.14 OWF44152.1 - 3e-19 68.9 0.1 5.2e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 COMM domain Helo_like_N PF17111.5 OWF44152.1 - 0.039 13.3 0.1 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Ribosomal_L9_N PF01281.19 OWF44153.1 - 6.5e-08 32.0 0.0 2.6e-07 30.1 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein L9, N-terminal domain SNAD4 PF18750.1 OWF44153.1 - 0.15 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 zf-RING_UBOX PF13445.6 OWF44154.1 - 1.6e-08 34.5 11.3 1.6e-08 34.5 11.3 2.7 4 0 0 4 4 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF44154.1 - 2.5e-07 30.9 9.7 2.5e-07 30.9 9.7 3.4 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 OWF44154.1 - 3.8e-07 29.9 10.4 3.8e-07 29.9 10.4 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF44154.1 - 8.3e-07 28.8 5.5 8.3e-07 28.8 5.5 4.3 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF44154.1 - 3.3e-06 27.2 11.8 3.3e-06 27.2 11.8 3.3 5 0 0 5 5 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 OWF44154.1 - 4.5e-06 26.7 5.1 4.5e-06 26.7 5.1 4.2 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF44154.1 - 5e-06 26.3 9.0 5e-06 26.3 9.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF44154.1 - 9.8e-06 25.4 9.2 9.8e-06 25.4 9.2 3.0 3 1 0 3 3 2 1 zinc-RING finger domain Baculo_PEP_C PF04513.12 OWF44154.1 - 0.015 15.3 3.9 0.015 15.3 3.9 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NHL PF01436.21 OWF44154.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 NHL repeat CspB_prodomain PF18425.1 OWF44154.1 - 0.046 13.7 0.3 0.19 11.7 0.0 2.1 1 1 1 2 2 2 0 Csp protease B prodomain Hex_IIIa PF02455.16 OWF44154.1 - 0.17 10.6 1.1 0.25 10.1 1.1 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) ApoLp-III PF07464.11 OWF44154.1 - 0.18 11.9 6.7 0.36 10.9 6.7 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1722 PF08349.11 OWF44154.1 - 0.26 11.6 1.9 0.98 9.7 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) ZYG-11_interact PF05884.12 OWF44154.1 - 0.31 10.4 2.0 0.47 9.8 2.0 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF948 PF06103.11 OWF44154.1 - 1.7 8.9 5.8 0.55 10.5 1.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mab-21 PF03281.14 OWF44156.1 - 2.8e-28 99.1 0.0 4.3e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_2 PF07719.17 OWF44156.1 - 0.11 12.7 0.0 0.44 10.8 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF44157.1 - 0.0068 16.7 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat AbiGii_2 PF16873.5 OWF44157.1 - 0.02 13.6 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGii toxin Spermine_synth PF01564.17 OWF44157.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain TPR_2 PF07719.17 OWF44157.1 - 0.23 11.7 1.0 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Mab-21 PF03281.14 OWF44158.1 - 5.4e-31 108.0 0.2 8.2e-31 107.4 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF44158.1 - 0.0042 17.4 0.0 0.45 10.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF44158.1 - 0.038 13.8 0.0 8.3 6.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF44158.1 - 0.063 13.4 0.1 4 7.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NTP_transf_2 PF01909.23 OWF44158.1 - 0.068 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain TPR_17 PF13431.6 OWF44158.1 - 0.12 12.8 0.1 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 OWF44159.1 - 3.6e-82 276.0 0.0 4.2e-82 275.8 0.0 1.0 1 0 0 1 1 1 1 SAC3/GANP family Ras PF00071.22 OWF44160.1 - 2.2e-54 183.4 0.0 2.6e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF44160.1 - 1.5e-31 109.1 0.0 2.1e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF44160.1 - 2.1e-12 46.8 0.0 3.6e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF44160.1 - 0.00012 22.0 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF44160.1 - 0.00095 19.2 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF44160.1 - 0.0027 17.3 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF44160.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 OWF44160.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain Med25 PF11232.8 OWF44162.1 - 1.1e-49 168.3 0.0 2.2e-49 167.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 COR PF16095.5 OWF44162.1 - 1.1e-19 71.0 0.0 3.1e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF44162.1 - 1.1e-12 48.2 0.1 9e-08 32.4 0.1 3.2 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF44162.1 - 1.6e-10 41.0 0.0 4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Death domain Ras PF00071.22 OWF44162.1 - 0.014 15.0 0.1 5.7 6.5 0.0 2.7 3 0 0 3 3 3 0 Ras family PduV-EutP PF10662.9 OWF44162.1 - 0.052 13.3 0.0 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OWF44162.1 - 0.074 13.1 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF44162.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NDUF_B12 PF08122.12 OWF44164.1 - 7.5e-08 32.3 0.7 1.8e-07 31.1 0.7 1.6 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Peptidase_C14 PF00656.22 OWF44165.1 - 1e-10 42.0 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Mor PF08765.11 OWF44165.1 - 0.09 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family Sec20 PF03908.13 OWF44166.1 - 0.94 9.4 7.4 1.8 8.5 7.4 1.5 1 1 0 1 1 1 0 Sec20 RhoGEF PF00621.20 OWF44167.1 - 7.5e-73 244.7 7.1 1.9e-37 129.3 0.3 5.7 5 2 1 6 6 5 2 RhoGEF domain Pkinase PF00069.25 OWF44167.1 - 1.1e-52 179.0 0.0 2.8e-52 177.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Spectrin PF00435.21 OWF44167.1 - 1.1e-39 135.1 67.2 3.4e-09 37.1 0.5 10.4 10 1 0 10 10 10 6 Spectrin repeat Pkinase_Tyr PF07714.17 OWF44167.1 - 1.4e-23 83.6 0.0 2.7e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 OWF44167.1 - 5.8e-19 68.0 2.0 1.2e-18 67.0 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain fn3 PF00041.21 OWF44167.1 - 7e-13 48.7 0.2 1.9e-12 47.3 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III domain PH PF00169.29 OWF44167.1 - 2.4e-12 47.3 0.2 0.00013 22.4 0.0 3.2 2 0 0 2 2 2 2 PH domain Ig_3 PF13927.6 OWF44167.1 - 5.9e-12 46.0 0.5 1.9e-11 44.4 0.5 2.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 OWF44167.1 - 1.2e-11 44.6 0.1 3.6e-11 43.1 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain SH3_2 PF07653.17 OWF44167.1 - 1.2e-07 31.3 0.0 0.0088 15.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OWF44167.1 - 1.9e-07 30.6 0.0 0.0094 15.5 0.0 2.9 2 0 0 2 2 2 2 SH3 domain Ig_2 PF13895.6 OWF44167.1 - 2.6e-06 27.7 0.3 7.4e-06 26.2 0.3 1.8 1 0 0 1 1 1 1 Immunoglobulin domain CRAL_TRIO_2 PF13716.6 OWF44167.1 - 2.7e-06 27.6 0.0 7.6e-05 22.9 0.0 3.2 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain V-set PF07686.17 OWF44167.1 - 5.3e-06 26.6 0.4 0.00053 20.1 0.3 3.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain PH_10 PF15411.6 OWF44167.1 - 1e-05 25.8 0.7 0.024 14.9 0.1 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain CRAL_TRIO PF00650.20 OWF44167.1 - 0.00033 20.4 0.1 0.0015 18.3 0.0 2.3 2 1 0 2 2 2 1 CRAL/TRIO domain SH3-RhoG_link PF16609.5 OWF44167.1 - 0.0033 17.2 13.8 0.43 10.3 13.8 2.7 1 1 0 1 1 1 1 SH3-RhoGEF linking unstructured region SH3_9 PF14604.6 OWF44167.1 - 0.012 15.5 0.0 2.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Variant SH3 domain APH PF01636.23 OWF44167.1 - 0.57 10.0 3.9 2.9 7.7 0.0 3.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family YoaP PF14268.6 OWF44168.1 - 0.0072 15.8 2.1 74 3.0 0.0 7.0 3 2 3 6 6 6 0 YoaP-like ZirS_C PF16583.5 OWF44168.1 - 0.15 11.6 7.6 0.89 9.1 0.4 3.0 1 1 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain Peptidase_S41_N PF11918.8 OWF44168.1 - 5 7.4 27.7 1.8e+03 -0.9 8.8 6.8 1 1 1 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Ank_2 PF12796.7 OWF44169.1 - 6.2e-207 670.8 127.2 1.4e-12 48.0 0.3 20.0 1 1 23 24 24 24 23 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF44169.1 - 9.8e-142 443.4 37.8 0.05 14.2 0.1 41.2 41 0 0 41 41 41 36 Ankyrin repeat Ank_5 PF13857.6 OWF44169.1 - 5.4e-140 453.6 32.4 4.1e-06 27.0 0.0 26.9 10 7 18 30 30 30 28 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF44169.1 - 3.3e-135 438.9 61.6 3.2e-06 27.6 0.0 22.6 21 2 1 22 22 22 21 Ankyrin repeats (many copies) Ank PF00023.30 OWF44169.1 - 2.3e-52 173.2 19.1 1.9 9.1 0.0 36.8 39 1 0 39 39 39 2 Ankyrin repeat DUF5388 PF17363.2 OWF44169.1 - 2e-20 72.8 6.9 7.8 6.8 0.0 18.2 20 0 0 20 20 20 1 Family of unknown function (DUF5388) Ferritin-like PF12902.7 OWF44169.1 - 6.7e-16 58.8 0.0 29 4.4 0.0 14.8 8 6 7 17 17 17 0 Ferritin-like DUF3349 PF11829.8 OWF44169.1 - 9.2e-13 48.8 0.0 53 4.7 0.0 12.4 14 0 0 14 14 13 0 Protein of unknown function (DUF3349) NTF2 PF02136.20 OWF44169.1 - 3.1e-08 34.2 14.2 12 6.4 0.0 11.7 12 3 3 15 15 14 1 Nuclear transport factor 2 (NTF2) domain CdhD PF03599.16 OWF44169.1 - 4.8e-08 32.1 17.3 33 3.0 0.0 14.9 16 3 3 19 19 19 0 CO dehydrogenase/acetyl-CoA synthase delta subunit TcdA_TcdB PF12919.7 OWF44169.1 - 8.3e-08 31.9 0.1 51 3.0 0.0 9.9 5 5 4 9 9 9 0 TcdA/TcdB catalytic glycosyltransferase domain DUF1844 PF08899.11 OWF44169.1 - 0.00013 22.2 19.7 25 5.3 0.0 13.0 17 0 0 17 17 17 0 Domain of unknown function (DUF1844) Beta_helix_2 PF18835.1 OWF44169.1 - 0.00035 20.3 25.9 46 3.9 0.1 11.7 15 0 0 15 15 15 0 Beta helix repeat of Inulin fructotransferase DUF3447 PF11929.8 OWF44169.1 - 2 8.4 87.8 0.021 14.8 4.9 18.1 2 2 19 21 21 21 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OWF44170.1 - 2.8e-33 114.3 10.4 1.2e-16 61.1 0.2 5.3 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF44170.1 - 3e-30 104.2 6.2 1.1e-08 35.4 0.0 6.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44170.1 - 2.7e-25 85.7 11.0 0.0004 20.6 0.0 9.6 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OWF44170.1 - 2.3e-23 81.9 10.7 5e-07 29.9 0.1 7.5 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF44170.1 - 1.1e-22 79.4 8.2 0.0059 17.0 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat TPR_12 PF13424.6 OWF44170.1 - 0.00017 21.8 0.0 0.035 14.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF44170.1 - 0.38 11.0 1.7 6.5 7.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 OWF44171.1 - 7.8e-15 54.3 59.6 0.028 15.3 2.2 10.4 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF44171.1 - 4.9e-09 36.2 60.6 0.0028 18.0 2.4 9.8 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 OWF44171.1 - 4.1e-07 30.7 40.2 0.00099 19.8 5.3 9.4 7 1 1 8 8 8 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 OWF44171.1 - 0.00014 21.8 9.2 0.00082 19.3 0.4 6.6 9 0 0 9 9 7 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OWF44171.1 - 0.00078 19.0 18.2 0.092 12.4 0.4 5.5 4 1 1 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 OWF44171.1 - 0.0012 18.5 24.8 0.36 10.6 1.0 6.5 6 0 0 6 6 6 3 zinc-finger C2H2-type zf_Hakai PF18408.1 OWF44171.1 - 0.002 17.8 3.6 1.3 8.8 0.0 4.1 3 0 0 3 3 3 1 C2H2 Hakai zinc finger domain zf_CCCH_4 PF18345.1 OWF44171.1 - 0.029 14.4 10.8 0.074 13.1 10.8 1.8 1 0 0 1 1 1 0 Zinc finger domain LPD3 PF18798.1 OWF44171.1 - 0.032 14.5 3.4 0.092 13.0 0.1 3.4 4 0 0 4 4 4 0 Large polyvalent protein-associated domain 3 zf-RING_14 PF17978.1 OWF44171.1 - 0.076 13.4 3.5 0.23 11.9 3.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CCCH PF00642.24 OWF44171.1 - 0.34 10.9 9.0 0.91 9.5 9.0 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OWF44171.1 - 1.1 9.2 11.3 3.4 7.6 11.3 1.9 1 0 0 1 1 1 0 CCCH-type zinc finger Laminin_EGF PF00053.24 OWF44172.1 - 8e-32 109.2 482.7 3.3e-05 23.9 10.6 24.7 13 4 13 26 26 26 18 Laminin EGF domain Laminin_G_3 PF13385.6 OWF44172.1 - 1.8e-19 70.4 0.1 3.5e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 OWF44172.1 - 4.2e-05 23.8 46.2 0.00031 21.1 9.6 33.5 31 7 3 34 34 34 15 EGF-like domain EGF PF00008.27 OWF44172.1 - 6.1e-05 23.2 5.4 6.1e-05 23.2 5.4 26.3 25 3 0 25 25 25 7 EGF-like domain Laminin_G_1 PF00054.23 OWF44172.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF99 PF01949.16 OWF44173.1 - 5.7e-06 25.9 3.9 12 5.2 0.0 7.0 7 2 1 8 8 8 2 Protein of unknown function DUF99 BPL_C PF02237.17 OWF44173.1 - 0.0017 18.2 16.3 40 4.2 0.1 9.1 9 1 1 10 10 10 1 Biotin protein ligase C terminal domain Periviscerokin PF08259.11 OWF44173.1 - 0.077 13.3 13.5 2e+02 2.8 0.0 9.0 12 0 0 12 12 12 0 Periviscerokinin family THDPS_M PF14789.6 OWF44173.1 - 1 9.5 4.8 3.8e+02 1.3 0.0 6.0 7 2 2 9 9 9 0 Tetrahydrodipicolinate N-succinyltransferase middle FAIM1 PF06905.13 OWF44174.1 - 2.5e-69 232.5 3.6 2.8e-69 232.3 3.6 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DUF4941 PF16299.5 OWF44174.1 - 0.037 13.3 0.1 0.043 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4941) zf-RING_UBOX PF13445.6 OWF44175.1 - 1.4e-08 34.6 8.9 1.4e-08 34.6 8.9 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF44175.1 - 8.8e-07 28.7 5.0 8.8e-07 28.7 5.0 3.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF44175.1 - 1.7e-06 28.1 9.8 1.7e-06 28.1 9.8 2.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF44175.1 - 4.8e-06 26.3 7.5 4.8e-06 26.3 7.5 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF44175.1 - 8.1e-06 26.1 8.3 8.1e-06 26.1 8.3 3.5 2 1 0 2 2 2 1 Ring finger domain zf-B_box PF00643.24 OWF44175.1 - 2.5e-05 24.3 4.4 2.5e-05 24.3 4.4 4.0 3 2 0 3 3 3 2 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF44175.1 - 6.2e-05 22.8 6.8 6.2e-05 22.8 6.8 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF44175.1 - 0.00079 19.3 6.2 0.00079 19.3 6.2 3.5 3 2 1 4 4 4 1 zinc-RING finger domain zf-RING_6 PF14835.6 OWF44175.1 - 0.038 13.8 3.3 0.12 12.3 3.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein BNR_6 PF15899.5 OWF44176.1 - 0.0012 18.7 7.5 5.8 7.3 0.2 3.5 3 0 0 3 3 3 3 BNR-Asp box repeat HLH PF00010.26 OWF44177.1 - 3.3e-12 46.2 4.9 4.7e-12 45.7 0.1 2.7 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF445 PF04286.12 OWF44177.1 - 0.53 10.0 1.5 0.76 9.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CDC45 PF02724.14 OWF44177.1 - 6.9 4.8 8.8 9.7 4.3 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein GYF_2 PF14237.6 OWF44178.1 - 1.1e-17 63.5 0.5 2.9e-17 62.2 0.5 1.8 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 OWF44178.1 - 6.4e-14 51.8 0.9 1.6e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain Arm PF00514.23 OWF44178.1 - 0.96 9.6 2.9 35 4.6 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat LRR_8 PF13855.6 OWF44179.1 - 7.7e-70 230.6 66.2 7.2e-13 48.1 1.2 11.6 6 2 5 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 OWF44179.1 - 3.4e-60 199.0 70.7 1.8e-06 28.2 0.9 12.7 12 0 0 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF44179.1 - 9.4e-14 51.3 41.7 8.4e-07 28.7 5.5 7.2 1 1 7 8 8 8 6 Leucine-rich repeat LRR_1 PF00560.33 OWF44179.1 - 4.6e-10 38.6 57.7 1.7 9.5 0.0 18.6 18 2 0 18 18 18 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 OWF44179.1 - 3.8e-06 26.9 1.1 10 6.3 0.0 8.1 8 3 2 10 10 10 1 RsmF rRNA methyltransferase first C-terminal domain Death PF00531.22 OWF44179.1 - 5.6e-05 23.2 0.0 0.00097 19.3 0.0 3.2 3 0 0 3 3 3 1 Death domain LRR_5 PF13306.6 OWF44179.1 - 0.00096 19.1 5.0 5.2 7.0 0.3 5.1 4 2 0 5 5 5 1 BspA type Leucine rich repeat region (6 copies) Methyltransf_11 PF08241.12 OWF44180.1 - 6.2e-21 74.9 0.0 1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44180.1 - 2.6e-19 69.7 0.0 4.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF44180.1 - 3.5e-15 56.1 0.0 4.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44180.1 - 3.3e-12 47.0 0.0 5.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF44180.1 - 9.2e-10 38.6 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44180.1 - 4.8e-09 35.9 0.0 6.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OWF44180.1 - 4.4e-06 26.4 0.0 6.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 OWF44180.1 - 0.00016 21.6 0.0 0.00049 20.0 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 OWF44180.1 - 0.0016 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 OWF44180.1 - 0.0027 17.2 0.0 0.75 9.2 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_32 PF13679.6 OWF44180.1 - 0.014 15.4 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 OWF44180.1 - 0.022 13.4 0.0 0.043 12.4 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 OWF44180.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 OWF44180.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 OWF44180.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 OWF44180.1 - 0.19 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) EMC3_TMCO1 PF01956.16 OWF44181.1 - 0.0011 18.7 1.5 0.0015 18.3 1.5 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Tetraspanin PF00335.20 OWF44181.1 - 0.011 15.5 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DivIC PF04977.15 OWF44181.1 - 0.012 15.3 4.3 0.02 14.6 4.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Phage_Gp23 PF10669.9 OWF44181.1 - 0.017 15.4 1.3 0.027 14.8 1.3 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HemX PF04375.14 OWF44181.1 - 0.029 13.7 4.9 0.038 13.3 4.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SlyX PF04102.12 OWF44181.1 - 0.047 14.3 5.9 0.08 13.6 5.9 1.2 1 0 0 1 1 1 0 SlyX TLP-20 PF06088.11 OWF44181.1 - 0.066 13.1 2.6 0.11 12.4 2.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2570 PF10828.8 OWF44181.1 - 0.081 12.7 7.9 0.15 11.9 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1178 PF06676.11 OWF44181.1 - 0.1 13.0 1.7 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) DUF4446 PF14584.6 OWF44181.1 - 0.12 12.3 2.7 0.19 11.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) O-antigen_lig PF13425.6 OWF44181.1 - 0.43 9.3 3.2 0.63 8.8 3.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Atg14 PF10186.9 OWF44181.1 - 0.84 8.7 6.5 1.2 8.1 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 USP8_interact PF08941.10 OWF44181.1 - 1.3 8.8 4.2 2.1 8.2 4.2 1.3 1 0 0 1 1 1 0 USP8 interacting Death PF00531.22 OWF44182.1 - 3.8e-07 30.2 0.3 5.9e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 Death domain CoiA PF06054.11 OWF44182.1 - 0.0068 15.6 0.4 0.0073 15.5 0.4 1.0 1 0 0 1 1 1 1 Competence protein CoiA-like family CHAD PF05235.14 OWF44182.1 - 0.014 15.4 0.0 0.015 15.2 0.0 1.0 1 0 0 1 1 1 0 CHAD domain MRG PF05712.13 OWF44182.1 - 0.026 13.8 0.3 0.028 13.7 0.3 1.1 1 0 0 1 1 1 0 MRG BACK PF07707.15 OWF44182.1 - 0.028 14.5 0.3 0.035 14.2 0.3 1.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch DUF4757 PF15949.5 OWF44182.1 - 0.031 14.7 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) HSR PF03172.13 OWF44182.1 - 0.068 13.3 0.5 0.1 12.7 0.5 1.3 1 1 0 1 1 1 0 HSR domain Glyco_tran_10_N PF17039.5 OWF44183.1 - 2.8e-09 37.4 0.4 1.3e-08 35.2 0.2 2.0 1 1 1 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 OWF44183.1 - 5.4e-06 26.2 0.5 1.3e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Fur_reg_FbpA PF13076.6 OWF44183.1 - 0.15 11.8 0.0 3.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Fur-regulated basic protein A Glyco_transf_10 PF00852.19 OWF44184.1 - 2.5e-35 121.8 1.4 2.9e-35 121.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_transf_10 PF00852.19 OWF44185.1 - 5.1e-47 159.9 1.2 9.4e-47 159.0 1.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF44185.1 - 1.9e-19 70.1 0.8 4.8e-19 68.9 0.4 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal UCH PF00443.29 OWF44186.1 - 3.8e-37 128.2 0.3 6.2e-37 127.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF44186.1 - 3.3e-11 43.4 0.2 3.3e-11 43.4 0.2 2.8 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_4 PF15227.6 OWF44187.1 - 0.00046 20.3 103.6 0.0076 16.4 1.8 12.9 12 1 0 12 12 12 7 zinc finger of C3HC4-type, RING HCMV_UL139 PF12507.8 OWF44187.1 - 0.068 13.6 3.4 93 3.4 0.0 4.7 5 0 0 5 5 5 0 Human Cytomegalovirus UL139 protein Gemini_AL1 PF00799.20 OWF44187.1 - 5 7.5 7.5 1.6 9.1 1.6 3.2 4 0 0 4 4 4 0 Geminivirus Rep catalytic domain Syndecan PF01034.20 OWF44189.1 - 0.0026 17.6 0.5 0.0056 16.6 0.5 1.5 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 OWF44189.1 - 0.0028 18.5 4.9 0.013 16.4 0.0 3.1 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain MRP-L27 PF09809.9 OWF44190.1 - 0.053 13.4 6.5 0.13 12.1 3.7 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L27 B12D PF06522.11 OWF44190.1 - 3 7.7 4.5 11 5.9 0.8 2.0 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit TcdB_N PF12918.7 OWF44190.1 - 5.8 7.3 13.6 7.7 6.9 2.7 2.2 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain Methyltransf_FA PF12248.8 OWF44191.1 - 3.5e-26 91.5 0.4 1.3e-11 44.7 0.0 2.6 2 0 0 2 2 2 2 Farnesoic acid 0-methyl transferase GPI PF06560.11 OWF44191.1 - 0.11 11.8 0.0 15 4.8 0.0 2.4 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Methylase_S PF01420.19 OWF44191.1 - 0.23 11.7 2.7 23 5.2 0.6 3.1 2 1 0 2 2 2 0 Type I restriction modification DNA specificity domain Hexapep PF00132.24 OWF44192.1 - 0.019 14.7 4.2 0.89 9.4 0.6 3.3 2 1 2 4 4 4 0 Bacterial transferase hexapeptide (six repeats) DUF3055 PF11256.8 OWF44192.1 - 0.032 14.5 0.0 0.74 10.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3055) PT-TG PF14449.6 OWF44192.1 - 3.4 7.6 29.2 1.3 9.0 2.5 5.9 1 1 5 6 6 6 0 Pre-toxin TG zf-C3HC4 PF00097.25 OWF44193.1 - 4.3e-05 23.3 12.4 4.3e-05 23.3 12.4 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF44193.1 - 0.00033 20.3 0.0 0.0027 17.3 0.0 2.3 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 OWF44193.1 - 0.0095 15.9 9.4 0.0095 15.9 9.4 3.4 3 0 0 3 3 3 1 RING-type zinc-finger NHL PF01436.21 OWF44193.1 - 0.014 15.4 0.0 11 6.3 0.0 4.0 3 0 0 3 3 3 0 NHL repeat Baculo_PEP_C PF04513.12 OWF44193.1 - 0.066 13.2 0.6 0.12 12.4 0.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_8 PF13855.6 OWF44194.1 - 4.1e-36 122.5 51.6 1.7e-06 27.7 1.7 10.1 7 3 4 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 OWF44194.1 - 3e-30 103.8 57.0 0.00023 21.5 1.1 12.8 9 2 6 15 15 15 12 Leucine Rich repeats (2 copies) PP2C PF00481.21 OWF44194.1 - 1.4e-29 103.5 0.0 2.7e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PH PF00169.29 OWF44194.1 - 2.3e-06 28.1 0.0 6.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 PH domain LRR_6 PF13516.6 OWF44194.1 - 7.6e-06 25.6 42.8 4.6 7.6 0.0 13.5 14 0 0 14 14 14 4 Leucine Rich repeat LRR_9 PF14580.6 OWF44194.1 - 2.5e-05 23.9 21.9 0.0012 18.4 1.7 4.9 2 2 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OWF44194.1 - 3e-05 24.0 38.0 15 6.6 0.1 14.7 15 1 0 15 15 15 2 Leucine Rich Repeat TSNAXIP1_N PF15739.5 OWF44195.1 - 4.5e-31 107.5 5.3 4.5e-31 107.5 5.3 2.9 1 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus Alpha_L_fucos PF01120.17 OWF44195.1 - 0.0093 15.5 3.5 0.023 14.2 3.5 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase ZapB PF06005.12 OWF44195.1 - 0.022 15.2 14.4 3.7 8.1 0.6 4.1 3 0 0 3 3 3 0 Cell division protein ZapB DUF2280 PF10045.9 OWF44195.1 - 0.027 14.7 0.3 0.12 12.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) TPR_MLP1_2 PF07926.12 OWF44195.1 - 0.7 10.0 21.4 0.21 11.7 8.7 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OWF44195.1 - 3.3 7.8 16.8 0.099 12.7 7.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CLTH PF10607.9 OWF44196.1 - 7.5e-43 145.9 0.0 1.2e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 OWF44196.1 - 4.7e-26 91.3 0.2 9.8e-26 90.2 0.2 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 OWF44196.1 - 5.3e-07 29.4 0.0 2e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 LisH Herpes_DNAp_acc PF04929.12 OWF44196.1 - 0.79 8.6 5.2 1.2 8.0 5.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF563 PF04577.14 OWF44197.1 - 3.9e-25 89.2 0.1 6.7e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) 7tm_1 PF00001.21 OWF44198.1 - 0.008 15.5 24.8 0.013 14.9 24.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glutaredoxin PF00462.24 OWF44198.1 - 0.0092 16.2 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin Coiled PF05710.12 OWF44199.1 - 0.91 10.4 12.6 0.19 12.6 8.5 2.0 1 1 1 2 2 2 0 Coiled coil COesterase PF00135.28 OWF44200.1 - 7e-118 394.7 0.0 1e-117 394.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF44200.1 - 4.9e-08 33.1 0.4 9.2e-07 28.9 0.4 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Alkyl_sulf_dimr PF14863.6 OWF44201.1 - 2.1e-45 154.6 0.1 3.2e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 OWF44201.1 - 5.7e-18 65.6 0.0 1.4e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 OWF44201.1 - 1.5e-09 38.2 0.0 9.1e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 OWF44201.1 - 3.7e-07 29.9 0.0 9.2e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SCP2 PF02036.17 OWF44201.1 - 5.8e-05 23.5 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family CpeT PF06206.11 OWF44202.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) BAR_3 PF16746.5 OWF44204.1 - 1.2e-68 231.3 20.2 1.8e-68 230.8 20.2 1.3 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 OWF44204.1 - 2.7e-40 137.7 0.1 9.1e-40 136.0 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 OWF44204.1 - 5.5e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 OWF44204.1 - 2.2e-06 28.1 1.3 5.4e-06 26.9 0.7 2.0 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.28 OWF44204.1 - 9.2e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF44204.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Nitrate_red_del PF02613.15 OWF44204.1 - 0.41 10.7 1.7 3.7 7.5 0.4 2.3 2 0 0 2 2 2 0 Nitrate reductase delta subunit NOA36 PF06524.12 OWF44205.1 - 5.9e-120 400.2 56.3 1.1e-109 366.5 46.9 2.0 2 0 0 2 2 2 2 NOA36 protein UPF0547 PF10571.9 OWF44206.1 - 7e-09 35.6 11.8 7e-09 35.6 11.8 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 CAP_N PF01213.19 OWF44206.1 - 0.0021 17.6 6.8 0.0021 17.6 6.8 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PLAT PF01477.23 OWF44207.1 - 2.8e-22 79.5 0.0 4.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 OWF44207.1 - 0.0051 16.7 0.1 0.0081 16.1 0.1 1.3 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Lipoxygenase PF00305.19 OWF44208.1 - 7.1e-65 219.7 0.0 2.5e-64 217.9 0.0 1.6 1 1 0 1 1 1 1 Lipoxygenase PLAT PF01477.23 OWF44208.1 - 1.2e-19 71.0 0.2 2.8e-19 69.8 0.2 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Lipoxygenase PF00305.19 OWF44209.1 - 9e-64 216.1 0.0 1.5e-63 215.4 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.23 OWF44209.1 - 3.5e-16 59.8 0.6 8.7e-16 58.5 0.6 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 OWF44209.1 - 0.00026 20.9 0.5 0.00052 19.9 0.5 1.5 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) Lipoxygenase PF00305.19 OWF44210.1 - 2.6e-64 217.9 0.0 6.3e-64 216.6 0.0 1.5 1 1 1 2 2 2 1 Lipoxygenase PLAT PF01477.23 OWF44210.1 - 3.4e-22 79.2 0.8 7.9e-22 78.0 0.4 1.8 2 0 0 2 2 2 1 PLAT/LH2 domain ATS3 PF06232.11 OWF44210.1 - 0.0014 18.6 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) DUF1024 PF06260.12 OWF44212.1 - 0.0015 18.7 13.6 1.2e+02 3.1 0.0 9.4 2 2 8 12 12 12 0 Protein of unknown function (DUF1024) Anoct_dimer PF16178.5 OWF44212.1 - 0.0089 15.8 0.5 1.7e+02 1.8 0.0 7.3 7 3 1 8 8 8 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin LRR_6 PF13516.6 OWF44212.1 - 0.13 12.4 4.8 2.4 8.4 0.8 2.9 2 0 0 2 2 2 0 Leucine Rich repeat Lipoxygenase PF00305.19 OWF44213.1 - 5.5e-62 210.2 0.0 9.3e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.23 OWF44213.1 - 1.1e-15 58.2 0.2 2.4e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Matrilin_ccoil PF10393.9 OWF44213.1 - 0.053 13.4 0.9 0.12 12.3 0.9 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Lipoxygenase PF00305.19 OWF44214.1 - 4.2e-49 167.6 0.0 1.9e-31 109.2 0.0 2.4 1 1 2 3 3 3 2 Lipoxygenase PLAT PF01477.23 OWF44214.1 - 9.5e-17 61.7 0.3 2.1e-16 60.6 0.3 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Matrilin_ccoil PF10393.9 OWF44214.1 - 0.053 13.4 0.9 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin SRCR PF00530.18 OWF44215.1 - 4.9 7.7 8.4 26 5.4 1.3 3.5 2 1 2 4 4 4 0 Scavenger receptor cysteine-rich domain Lipoxygenase PF00305.19 OWF44216.1 - 1.5e-28 99.6 0.1 2.2e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.23 OWF44216.1 - 1e-11 45.4 0.1 2.3e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain PDZ PF00595.24 OWF44217.1 - 5.6e-08 33.0 0.1 1.3e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF44217.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Glyco_hydro_15 PF00723.21 OWF44218.1 - 6.2e-158 526.3 0.0 7.6e-158 526.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 UcrQ PF02939.16 OWF44219.1 - 6.8e-19 67.6 0.3 7.8e-19 67.4 0.3 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 OWF44219.1 - 0.00012 22.3 0.1 0.00015 22.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 COMM_domain PF07258.14 OWF44220.1 - 6.7e-18 64.6 0.5 1.4e-17 63.6 0.5 1.5 1 0 0 1 1 1 1 COMM domain SAM_KSR1 PF13543.6 OWF44220.1 - 0.0012 18.9 1.7 0.0018 18.4 0.5 1.8 2 0 0 2 2 2 1 SAM like domain present in kinase suppressor RAS 1 Phe_tRNA-synt_N PF02912.18 OWF44220.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1492 PF07374.11 OWF44220.1 - 0.064 13.4 2.3 0.15 12.2 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) PhoLip_ATPase_C PF16212.5 OWF44221.1 - 8.1e-65 219.0 24.0 8.1e-65 219.0 24.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OWF44221.1 - 3.5e-22 77.9 1.4 3.5e-22 77.9 1.4 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OWF44221.1 - 2.6e-10 40.9 0.2 2.8e-05 24.5 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OWF44221.1 - 4.1e-10 39.6 0.0 7.6e-08 32.3 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OWF44221.1 - 2.2e-08 33.8 0.2 2e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OWF44221.1 - 4e-05 23.5 0.4 0.00023 21.0 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase VPS28 PF03997.12 OWF44221.1 - 0.0019 17.9 0.3 0.0039 16.9 0.3 1.5 1 0 0 1 1 1 1 VPS28 protein YjeF_N PF03853.15 OWF44221.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Spt20 PF12090.8 OWF44222.1 - 3e-30 105.6 0.2 3.8e-18 65.9 0.0 4.3 3 2 1 4 4 4 2 Spt20 family PBP_N PF17093.5 OWF44222.1 - 6.1 7.1 5.3 1.6 9.0 1.6 1.8 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus DUF2121 PF09894.9 OWF44223.1 - 9.3e-12 44.9 17.6 0.0055 16.3 0.0 6.0 1 1 7 8 8 8 8 Uncharacterized protein conserved in archaea (DUF2121) SASP_gamma PF04259.14 OWF44223.1 - 6.3e-05 23.4 0.2 4.7 7.8 0.0 4.5 1 1 5 6 6 6 3 Small, acid-soluble spore protein, gamma-type RcsD_ABL PF16359.5 OWF44223.1 - 0.0016 18.5 0.2 60 3.8 0.0 5.8 2 1 4 8 8 8 0 RcsD-ABL domain DUF5007 PF16398.5 OWF44223.1 - 0.047 13.4 2.9 5.7 6.5 0.1 3.3 3 1 0 4 4 4 0 Domain of unknown function (DUF5007) Myelin_PLP PF01275.19 OWF44224.1 - 4.5e-27 95.5 8.4 1.6e-26 93.6 8.4 1.8 1 1 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Trypan_PARP PF05887.11 OWF44224.1 - 0.74 9.8 38.6 1.8 8.5 36.6 2.4 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) W2 PF02020.18 OWF44225.1 - 9.9e-19 67.3 3.6 9.9e-19 67.3 3.6 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OWF44225.1 - 5.1e-12 45.0 12.1 1.7e-06 27.5 2.9 4.8 2 1 3 5 5 5 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OWF44225.1 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 OWF44225.1 - 0.00023 20.9 7.7 0.0026 17.5 1.0 3.7 2 1 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 OWF44225.1 - 0.0014 19.0 0.0 0.0025 18.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 OWF44225.1 - 0.0035 16.3 0.3 0.0073 15.3 0.3 1.5 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 OWF44225.1 - 0.0035 15.5 0.3 0.0085 14.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) GLTP PF08718.11 OWF44225.1 - 0.16 12.3 0.0 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) UDPG_MGDP_dh_N PF03721.14 OWF44226.1 - 2.6e-64 216.3 0.1 4.2e-64 215.6 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OWF44226.1 - 6.8e-35 119.7 0.0 1.1e-33 115.7 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OWF44226.1 - 7.1e-32 109.5 0.1 1.7e-31 108.3 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 OWF44226.1 - 0.00037 20.7 0.0 0.021 15.0 0.0 2.7 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PTS-HPr PF00381.19 OWF44226.1 - 0.038 14.2 0.3 0.098 12.9 0.3 1.7 1 0 0 1 1 1 0 PTS HPr component phosphorylation site 4HBT_2 PF13279.6 OWF44227.1 - 2.7e-20 73.1 0.0 3.6e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF44227.1 - 0.065 12.5 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase Glucosamine_iso PF01182.20 OWF44228.1 - 9.2e-21 74.8 0.0 1.3e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AAA_2 PF07724.14 OWF44229.1 - 2.4e-44 151.5 0.1 5.2e-44 150.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_5 PF13857.6 OWF44229.1 - 7.9e-19 67.5 0.9 5e-08 33.1 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF44229.1 - 1.2e-17 63.4 0.7 8.8e-08 32.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OWF44229.1 - 2.6e-17 63.2 0.0 9.9e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF44229.1 - 1.8e-15 55.5 0.1 1.6e-05 24.9 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OWF44229.1 - 1.5e-13 50.9 0.0 4.4e-09 36.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) ClpB_D2-small PF10431.9 OWF44229.1 - 7.1e-10 38.8 0.3 3.7e-09 36.5 0.0 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OWF44229.1 - 4.7e-09 36.8 0.2 1.5e-07 31.9 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF44229.1 - 5.5e-09 36.1 0.0 2.4e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OWF44229.1 - 5.4e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 OWF44229.1 - 0.00027 21.3 0.2 0.0058 17.0 0.1 2.9 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 OWF44229.1 - 0.00048 19.5 0.1 0.0012 18.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin YchF-GTPase_C PF06071.13 OWF44229.1 - 0.0019 18.4 0.0 0.0063 16.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) AAA_24 PF13479.6 OWF44229.1 - 0.0029 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 OWF44229.1 - 0.0045 17.1 0.0 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 Torsin ATPase_2 PF01637.18 OWF44229.1 - 0.0081 16.1 0.3 0.14 12.1 0.0 2.9 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 OWF44229.1 - 0.011 15.5 0.0 0.11 12.4 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF44229.1 - 0.016 15.5 0.0 0.053 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF44229.1 - 0.081 13.1 0.2 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF44229.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region UCH PF00443.29 OWF44230.1 - 3.7e-41 141.3 0.1 5.6e-41 140.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF44230.1 - 3.4e-24 86.0 0.0 1.5e-23 83.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPAP3_C PF13877.6 OWF44231.1 - 0.063 13.8 0.1 0.42 11.2 0.0 2.3 2 1 1 3 3 3 0 Potential Monad-binding region of RPAP3 Sushi PF00084.20 OWF44232.1 - 0.00029 21.4 2.3 0.00029 21.4 2.3 3.3 3 1 0 3 3 3 1 Sushi repeat (SCR repeat) zf-TFIIB PF13453.6 OWF44232.1 - 0.18 11.2 4.1 2.7 7.4 0.1 3.5 4 0 0 4 4 4 0 Transcription factor zinc-finger Ank_2 PF12796.7 OWF44233.1 - 3.5e-15 56.3 0.0 7.7e-05 23.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) COR PF16095.5 OWF44233.1 - 3.5e-14 53.1 0.7 8.5e-14 51.8 0.3 1.9 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF44233.1 - 1.7e-11 44.4 0.0 7e-06 26.3 0.0 2.9 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ank_4 PF13637.6 OWF44233.1 - 1.6e-06 28.6 0.1 0.11 13.1 0.0 4.0 3 1 2 5 5 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF44233.1 - 4.5e-06 26.8 1.8 0.017 15.4 0.2 3.9 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ras PF00071.22 OWF44233.1 - 0.00012 21.7 0.0 0.089 12.4 0.0 2.6 2 0 0 2 2 2 2 Ras family Ank_3 PF13606.6 OWF44233.1 - 0.00031 21.0 0.2 53 4.9 0.0 5.6 6 0 0 6 6 6 0 Ankyrin repeat Arf PF00025.21 OWF44233.1 - 0.012 15.1 0.2 0.034 13.6 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF5305 PF17231.2 OWF44233.1 - 0.013 14.9 0.2 0.19 11.1 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5305) MMR_HSR1 PF01926.23 OWF44233.1 - 0.02 15.0 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 OWF44233.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OWF44233.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain DASH_Dad4 PF08650.10 OWF44233.1 - 2.3 8.3 4.6 22 5.1 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF445 PF04286.12 OWF44234.1 - 4.9e-10 39.8 1.4 3.2e-08 33.8 1.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF445) Trigger_C PF05698.14 OWF44234.1 - 3.4e-05 23.9 3.3 5.5 7.0 0.0 5.4 1 1 4 5 5 5 2 Bacterial trigger factor protein (TF) C-terminus DUF2884 PF11101.8 OWF44234.1 - 0.0002 21.0 19.3 0.3 10.6 1.3 4.2 1 1 3 4 4 4 4 Protein of unknown function (DUF2884) AAA_15 PF13175.6 OWF44234.1 - 0.031 14.0 11.7 53 3.4 11.7 3.0 1 1 0 1 1 1 0 AAA ATPase domain DUF3819 PF12842.7 OWF44234.1 - 0.052 13.5 3.1 1.5e+02 2.3 3.1 5.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) Speriolin_N PF15058.6 OWF44234.1 - 10 6.2 16.6 9.9 6.2 1.7 3.9 1 1 2 3 3 3 0 Speriolin N terminus HEPN_DZIP3 PF18738.1 OWF44235.1 - 1.3e-27 96.3 0.1 3.8e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 DZIP3/ hRUL138-like HEPN Roc PF08477.13 OWF44235.1 - 1.2e-12 48.1 0.8 3.5e-06 27.2 0.1 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF44235.1 - 1e-11 45.0 0.4 5.6e-11 42.6 0.3 2.4 2 1 0 2 2 2 1 C-terminal of Roc, COR, domain Ras PF00071.22 OWF44235.1 - 4.1e-05 23.2 0.7 0.23 11.1 0.0 2.6 2 0 0 2 2 2 2 Ras family GTP_EFTU PF00009.27 OWF44235.1 - 0.00072 19.2 1.9 0.026 14.1 1.6 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 OWF44235.1 - 0.0053 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OWF44235.1 - 0.0088 16.2 0.0 0.055 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OWF44235.1 - 0.023 15.2 0.1 0.7 10.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 OWF44235.1 - 0.042 13.4 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OWF44235.1 - 0.043 13.6 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arf PF00025.21 OWF44235.1 - 0.05 13.1 1.0 1.5 8.3 0.2 3.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_22 PF13401.6 OWF44235.1 - 0.094 13.0 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Band_7 PF01145.25 OWF44236.1 - 3.8e-08 33.5 0.3 1.1e-07 32.0 0.3 1.8 1 1 0 1 1 1 1 SPFH domain / Band 7 family SKG6 PF08693.10 OWF44236.1 - 2 7.9 5.0 4 6.9 5.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TPR_1 PF00515.28 OWF44237.1 - 1.4e-45 151.3 4.1 1.5e-08 34.1 0.0 10.3 10 1 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 OWF44237.1 - 1.1e-34 115.7 2.8 1.6e-05 24.7 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 OWF44237.1 - 6.8e-33 110.1 1.2 0.00043 20.3 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF44237.1 - 7.8e-30 102.9 14.1 3.7e-20 71.9 1.2 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OWF44237.1 - 9.1e-27 92.5 0.8 1.3e-05 24.8 0.0 8.4 4 2 5 9 9 9 5 TPR repeat TPR_17 PF13431.6 OWF44237.1 - 6.9e-24 82.5 2.4 0.1 13.0 0.1 9.0 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 OWF44237.1 - 8.1e-23 80.5 2.2 0.00044 20.5 0.0 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 OWF44237.1 - 8.7e-23 80.7 0.0 2e-07 31.5 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF44237.1 - 1.1e-21 77.1 1.6 0.0069 16.9 0.0 7.1 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 OWF44237.1 - 1.6e-19 68.9 0.3 0.0021 18.7 0.0 8.9 5 1 4 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 OWF44237.1 - 1.2e-16 60.1 5.7 0.1 13.3 0.6 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 OWF44237.1 - 2e-15 55.6 3.3 0.0028 17.6 0.0 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF44237.1 - 7.9e-07 29.1 0.0 0.32 11.2 0.0 4.6 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 OWF44237.1 - 0.00025 20.4 0.0 5.3 6.2 0.0 4.3 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF44237.1 - 0.002 17.5 1.0 0.21 10.9 0.0 3.3 3 1 1 4 4 4 1 MalT-like TPR region TPR_20 PF14561.6 OWF44237.1 - 0.0027 18.0 0.1 0.024 15.0 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OWF44237.1 - 0.0046 17.0 3.6 0.72 9.9 0.1 3.7 3 1 1 4 4 4 1 Putative TPR-like repeat HobA PF12163.8 OWF44237.1 - 0.012 15.1 0.1 0.052 13.1 0.1 1.9 2 0 0 2 2 2 0 DNA replication regulator ChAPs PF09295.10 OWF44237.1 - 0.04 12.9 0.1 0.9 8.5 0.0 2.5 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.23 OWF44237.1 - 0.084 12.1 0.3 15 4.7 0.0 2.8 2 1 1 3 3 3 0 FAT domain TPR_10 PF13374.6 OWF44237.1 - 0.13 12.2 6.5 19 5.3 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat PPTA PF01239.22 OWF44237.1 - 0.16 11.8 7.1 1.1 9.1 0.2 3.9 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat DUF4192 PF13830.6 OWF44237.1 - 0.24 11.4 0.0 7.3 6.6 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4192) Band_7 PF01145.25 OWF44238.1 - 2.3e-10 40.8 0.7 1.4e-09 38.2 0.0 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family Tox-GHH PF15636.6 OWF44238.1 - 0.0025 17.8 0.4 0.0046 16.9 0.4 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin Col_cuticle_N PF01484.17 OWF44238.1 - 0.028 14.5 3.0 0.057 13.5 3.0 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DWNN PF08783.11 OWF44238.1 - 0.034 14.4 0.2 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 DWNN domain HEPN_DZIP3 PF18738.1 OWF44240.1 - 2e-31 108.7 0.0 2.8e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN HEPN_AbiU2 PF18734.1 OWF44240.1 - 0.078 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AbiU2 RAMA PF18755.1 OWF44241.1 - 1.1e-24 86.9 0.0 5.8e-24 84.6 0.0 2.1 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated JAB PF01398.21 OWF44241.1 - 3.4e-08 33.5 0.2 1.6e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OWF44241.1 - 5.4e-08 32.6 0.2 5.1e-07 29.5 0.1 2.4 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain FKBP_C PF00254.28 OWF44242.1 - 1.1e-28 99.4 0.0 1.5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 OWF44242.1 - 6.5e-09 34.7 1.7 0.0004 19.7 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OWF44242.1 - 5.6e-08 31.9 1.0 0.00087 18.7 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF44242.1 - 1.1e-06 28.1 0.8 0.026 14.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF44242.1 - 1.3e-06 28.7 0.2 2.3e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF44242.1 - 0.0046 16.8 0.9 0.91 9.4 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 OWF44242.1 - 0.13 12.2 0.8 3.8 7.5 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EphA2_TM PF14575.6 OWF44243.1 - 0.048 14.5 0.0 0.088 13.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myc_target_1 PF15179.6 OWF44243.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 STE2 PF02116.15 OWF44243.1 - 0.17 11.1 0.1 0.25 10.6 0.1 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR EGF PF00008.27 OWF44243.1 - 2.9 8.3 13.6 0.23 11.8 5.2 2.4 2 0 0 2 2 2 0 EGF-like domain DUF834 PF05754.14 OWF44244.1 - 0.0023 17.9 8.7 4 7.5 0.3 4.7 2 2 2 5 5 5 3 Domain of unknown function (DUF834) FBPase_glpX PF03320.13 OWF44244.1 - 3.3 6.5 6.7 9.4 5.0 0.2 3.2 1 1 3 4 4 4 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DUF2715 PF10895.8 OWF44246.1 - 0.047 13.3 0.5 14 5.3 0.5 3.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) Phenol_MetA_deg PF13557.6 OWF44246.1 - 0.19 11.6 9.8 27 4.6 0.2 4.0 1 1 3 4 4 4 0 Putative MetA-pathway of phenol degradation PH_17 PF18012.1 OWF44248.1 - 0.21 11.3 11.1 11 5.8 0.6 4.9 2 2 2 5 5 5 0 PH domain Coa1 PF08695.10 OWF44249.1 - 6.3e-08 32.4 0.0 1.9e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Coa1 PF08695.10 OWF44250.1 - 3.7e-07 29.9 0.0 5.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 tRNA-synt_1b PF00579.25 OWF44251.1 - 4.2e-71 239.6 0.0 5.1e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FAM101 PF15068.6 OWF44253.1 - 0.042 13.8 14.4 1.3 8.9 1.1 3.8 1 1 2 3 3 3 0 FAM101 family Peptidase_S49 PF01343.18 OWF44253.1 - 0.15 12.0 2.2 5.7 6.9 0.1 3.5 2 1 1 3 3 3 0 Peptidase family S49 HTH_psq PF05225.16 OWF44253.1 - 2.1 8.1 34.8 34 4.3 0.1 12.2 15 0 0 15 15 15 0 helix-turn-helix, Psq domain Glyco_transf_18 PF15024.6 OWF44254.1 - 8.3e-231 767.4 0.3 1e-230 767.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.6 OWF44254.1 - 1.7e-25 89.4 0.1 3.5e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DASH_Dad4 PF08650.10 OWF44254.1 - 0.17 11.9 2.2 0.67 10.0 1.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad4 Tuberin PF03542.16 OWF44256.1 - 0.053 12.6 0.2 6.3 5.8 0.0 2.2 1 1 1 2 2 2 0 Tuberin PUA_3 PF17785.1 OWF44256.1 - 0.12 12.2 4.8 37 4.2 0.1 5.0 2 2 5 7 7 7 0 PUA-like domain CDC73_N PF16050.5 OWF44257.1 - 7.9e-127 422.6 0.4 1.1e-126 422.1 0.4 1.2 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 OWF44257.1 - 3.7e-50 169.7 0.9 7e-50 168.8 0.9 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Glucosamine_iso PF01182.20 OWF44258.1 - 7e-69 232.1 0.0 7.9e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ALAD PF00490.21 OWF44259.1 - 1.3e-124 415.6 0.0 1.4e-124 415.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Rhomboid PF01694.22 OWF44260.1 - 3.4e-35 121.3 6.7 3.4e-35 121.3 6.7 1.7 2 0 0 2 2 2 1 Rhomboid family EF-hand_1 PF00036.32 OWF44260.1 - 0.00042 19.7 0.1 0.0011 18.4 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OWF44260.1 - 0.00089 19.7 0.5 0.0018 18.7 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF44260.1 - 0.0093 15.8 0.2 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF4311 PF14188.6 OWF44260.1 - 0.045 13.5 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) DUF2534 PF10749.9 OWF44260.1 - 0.076 13.2 0.7 0.22 11.7 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2534) Tail_VII PF17091.5 OWF44260.1 - 0.66 9.9 0.1 0.66 9.9 0.1 2.4 2 0 0 2 2 2 0 Inovirus G7P protein DUF3951 PF13131.6 OWF44260.1 - 3.3 8.0 5.8 4.5 7.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) AAA_11 PF13086.6 OWF44262.1 - 9.4e-16 58.4 1.7 9.4e-16 58.4 1.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF44262.1 - 1.9e-05 25.0 0.0 4.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OWF44262.1 - 0.00097 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OWF44262.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OWF44262.1 - 0.005 17.1 0.0 0.019 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OWF44262.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 OWF44262.1 - 0.02 15.3 0.1 0.07 13.5 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF44262.1 - 0.028 14.8 0.0 0.081 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 OWF44262.1 - 0.03 14.1 0.1 0.073 12.8 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 OWF44262.1 - 0.032 14.3 0.2 0.032 14.3 0.2 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 OWF44262.1 - 0.052 14.1 0.0 0.19 12.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OWF44262.1 - 0.066 13.0 0.0 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF44262.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OWF44262.1 - 0.14 12.6 0.1 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase HTH_45 PF14947.6 OWF44263.1 - 0.00064 19.7 29.6 4.4 7.4 3.7 6.3 1 1 5 6 6 6 6 Winged helix-turn-helix Pox_A3L PF05288.11 OWF44263.1 - 0.55 10.2 6.4 43 4.2 0.1 4.5 1 1 5 6 6 6 0 Poxvirus A3L Protein SNF PF00209.18 OWF44264.1 - 3.7e-62 210.7 11.6 4.2e-62 210.5 11.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF44265.1 - 8.1e-35 120.5 17.2 9.7e-35 120.2 17.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Carb_anhydrase PF00194.21 OWF44267.1 - 2.2e-70 237.1 0.0 2.7e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase LIG3_BRCT PF16759.5 OWF44267.1 - 0.18 12.1 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain E1_DerP2_DerF2 PF02221.15 OWF44268.1 - 5.9e-18 65.6 0.4 7.9e-18 65.2 0.4 1.2 1 0 0 1 1 1 1 ML domain Peptidase_C2 PF00648.21 OWF44269.1 - 3.6e-86 288.9 0.4 6.2e-86 288.1 0.4 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DZR PF12773.7 OWF44269.1 - 3.2e-05 23.9 17.3 0.00037 20.4 10.9 3.0 2 1 0 2 2 2 2 Double zinc ribbon zf-RanBP PF00641.18 OWF44269.1 - 0.017 14.5 31.0 0.02 14.2 5.1 4.7 4 1 1 5 5 5 0 Zn-finger in Ran binding protein and others Lipoprotein_2 PF00921.17 OWF44269.1 - 0.48 9.9 10.9 1.1 8.7 10.9 1.6 1 0 0 1 1 1 0 Borrelia lipoprotein Vps36-NZF-N PF16988.5 OWF44269.1 - 4.1 6.9 11.6 12 5.4 1.6 3.8 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TNFR_c6 PF00020.18 OWF44270.1 - 9.1e-09 35.6 4.2 9.1e-09 35.6 4.2 3.3 2 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region TNFR_c6 PF00020.18 OWF44271.1 - 2.6e-07 30.9 13.4 2.6e-07 30.9 13.4 3.6 3 1 1 4 4 4 2 TNFR/NGFR cysteine-rich region m04gp34like PF12216.8 OWF44271.1 - 0.0069 16.0 0.5 0.012 15.2 0.5 1.4 1 0 0 1 1 1 1 Immune evasion protein SID-1_RNA_chan PF13965.6 OWF44271.1 - 0.074 11.5 1.0 0.12 10.8 1.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3810 PF12725.7 OWF44271.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) IRK PF01007.20 OWF44271.1 - 0.13 12.1 0.5 0.22 11.3 0.5 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Death PF00531.22 OWF44273.1 - 4.3e-08 33.2 0.0 7.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.18 OWF44273.1 - 5.5e-08 33.1 21.5 1.3e-05 25.4 8.3 3.5 2 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region Sp38 PF07354.12 OWF44273.1 - 0.042 13.3 7.2 0.078 12.4 7.2 1.4 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) PRIMA1 PF16101.5 OWF44274.1 - 0.00057 19.9 0.0 0.00061 19.8 0.0 1.1 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DUF4448 PF14610.6 OWF44274.1 - 0.031 14.0 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) WBP-1 PF11669.8 OWF44274.1 - 0.12 13.0 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF4519 PF15012.6 OWF44274.1 - 0.14 12.4 0.6 0.22 11.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Calycin_like PF13944.6 OWF44275.1 - 0.027 14.8 0.1 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Calycin-like beta-barrel domain FAM220 PF15487.6 OWF44275.1 - 0.13 11.8 8.3 0.042 13.5 0.6 2.2 2 0 0 2 2 2 0 FAM220 family 7tm_1 PF00001.21 OWF44276.1 - 1.1e-17 64.3 18.3 1.4e-17 63.9 18.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 OWF44277.1 - 4.8e-17 62.2 17.5 4.8e-17 62.2 17.5 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF44277.1 - 1.3e-05 24.7 17.6 1.9e-05 24.2 17.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Orai-1 PF07856.12 OWF44277.1 - 3.4 7.3 8.1 0.12 12.1 1.6 1.9 2 1 0 2 2 2 0 Mediator of CRAC channel activity tRNA_U5-meth_tr PF05958.11 OWF44278.1 - 1.5e-18 66.9 0.0 2.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 OWF44278.1 - 1.1e-11 44.7 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44278.1 - 1e-09 39.0 0.1 3.2e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF44278.1 - 1.8e-08 34.2 0.1 9.2e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.14 OWF44278.1 - 1.2e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OWF44278.1 - 1.8e-07 31.1 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OWF44278.1 - 5.2e-07 29.4 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 OWF44278.1 - 1.5e-06 27.8 0.1 2.7e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 OWF44278.1 - 2.9e-05 23.6 0.2 5.6e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OWF44278.1 - 3.2e-05 24.5 0.1 7.7e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44278.1 - 3.3e-05 23.4 0.3 6.3e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 OWF44278.1 - 6.1e-05 23.0 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OWF44278.1 - 0.00028 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 OWF44278.1 - 0.0013 19.4 0.0 0.0039 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OWF44278.1 - 0.0039 17.1 0.4 0.0076 16.2 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF44278.1 - 0.0063 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OWF44278.1 - 0.0083 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 OWF44278.1 - 0.0092 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase N6_N4_Mtase PF01555.18 OWF44278.1 - 0.014 15.1 0.5 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 DNA methylase DOT1 PF08123.13 OWF44278.1 - 0.014 14.9 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF1364 PF07102.12 OWF44278.1 - 0.028 14.3 1.1 0.082 12.8 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) UPF0020 PF01170.18 OWF44278.1 - 0.031 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.9 OWF44278.1 - 0.077 12.7 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Lysine methyltransferase RRM_1 PF00076.22 OWF44278.1 - 0.079 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_repr_REX1B PF14966.6 OWF44279.1 - 0.021 15.5 0.7 0.021 15.5 0.7 1.9 2 1 0 2 2 2 0 DNA repair REX1-B T3SS_needle_F PF09392.10 OWF44279.1 - 0.56 10.4 3.0 2.6 8.3 0.6 2.7 2 1 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Exonuc_VII_L PF02601.15 OWF44279.1 - 0.75 9.3 8.2 1 8.8 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Orbi_VP5 PF00901.17 OWF44279.1 - 1.1 7.5 8.6 1.3 7.3 8.6 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 ALMT PF11744.8 OWF44279.1 - 1.3 7.7 9.0 1.9 7.2 9.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter APG6_N PF17675.1 OWF44279.1 - 1.5 9.3 22.4 1.2 9.6 9.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Phlebovirus_NSM PF07246.11 OWF44279.1 - 1.7 8.0 11.6 0.8 9.0 9.6 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Prominin PF05478.11 OWF44279.1 - 4.6 5.1 10.5 5.4 4.8 5.9 1.9 1 1 1 2 2 2 0 Prominin HR1 PF02185.16 OWF44279.1 - 8.8 6.5 19.0 3.1 8.0 2.8 3.1 1 1 1 2 2 2 0 Hr1 repeat SLX9 PF15341.6 OWF44279.1 - 9.2 6.7 16.7 21 5.5 16.7 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Rad60-SLD PF11976.8 OWF44280.1 - 4.3e-18 64.9 0.7 7.4e-11 41.7 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OWF44280.1 - 2.1e-08 33.8 0.3 0.00073 19.2 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin family MIEAP PF16026.5 OWF44280.1 - 0.033 14.4 0.8 0.067 13.4 0.8 1.4 1 0 0 1 1 1 0 Mitochondria-eating protein SCIMP PF15050.6 OWF44280.1 - 0.27 11.7 3.9 1.6 9.2 0.6 2.3 2 0 0 2 2 2 0 SCIMP protein Pkinase PF00069.25 OWF44281.1 - 3.5e-59 200.3 0.0 3.5e-59 200.3 0.0 3.5 3 1 0 3 3 3 1 Protein kinase domain CNH PF00780.22 OWF44281.1 - 3.8e-37 128.4 0.1 1.3e-36 126.6 0.1 2.0 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 OWF44281.1 - 6.9e-29 100.9 0.2 2.8e-28 98.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 OWF44281.1 - 3.2e-07 30.8 0.6 1.9e-06 28.3 0.0 2.8 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 OWF44281.1 - 0.62 10.0 13.5 0.043 13.7 1.2 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) XRCC1_N PF01834.16 OWF44282.1 - 1.8e-48 164.3 0.1 3.5e-48 163.4 0.1 1.5 1 0 0 1 1 1 1 XRCC1 N terminal domain SLD5_C PF16922.5 OWF44283.1 - 9.6 6.5 11.9 9.2 6.5 1.2 3.5 3 1 0 3 3 3 0 DNA replication complex GINS protein SLD5 C-terminus AltA1 PF16541.5 OWF44284.1 - 0.065 14.1 0.7 13 6.7 0.0 2.9 1 1 2 3 3 3 0 Alternaria alternata allergen 1 Yopt PF09467.10 OWF44284.1 - 0.14 12.2 9.2 3.2 7.9 0.1 3.7 1 1 2 3 3 3 0 Hypothetical protein Yopt TRP_N PF14558.6 OWF44284.1 - 0.29 11.5 3.4 5.6 7.3 3.4 2.3 1 1 0 1 1 1 0 ML-like domain DctA-YdbH PF11739.8 OWF44284.1 - 0.3 10.8 1.2 3 7.5 0.2 2.0 2 0 0 2 2 2 0 Dicarboxylate transport UPF0231 PF06062.11 OWF44284.1 - 0.32 11.3 3.9 1.9 8.7 0.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) DUF5376 PF17346.2 OWF44284.1 - 2.1 8.7 16.6 12 6.2 2.4 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5376) DUF3912 PF13051.6 OWF44284.1 - 8.1 6.8 15.9 31 4.9 2.0 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3912) Auts2 PF15336.6 OWF44286.1 - 1.9e-36 126.2 5.2 1.9e-36 126.2 5.2 5.9 4 2 1 6 6 6 1 Autism susceptibility gene 2 protein SGL PF08450.12 OWF44287.1 - 0.019 14.6 0.2 0.053 13.1 0.2 1.8 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF44287.1 - 0.035 14.2 3.4 0.94 9.6 0.5 4.1 4 0 0 4 4 4 0 NHL repeat F5_F8_type_C PF00754.25 OWF44288.1 - 1.2e-06 28.7 0.5 0.00052 20.1 0.2 2.8 2 0 0 2 2 2 2 F5/8 type C domain DUF908 PF06012.12 OWF44290.1 - 0.81 9.0 10.6 1.2 8.5 10.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MIF PF01187.18 OWF44291.1 - 2.4e-26 92.3 0.0 2.6e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF1904 PF08921.11 OWF44291.1 - 0.0076 16.6 0.0 0.0076 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1904) Aminopep PF10023.9 OWF44291.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase Tautomerase_3 PF14832.6 OWF44291.1 - 0.17 12.1 0.1 6.6 7.0 0.0 2.0 1 1 1 2 2 2 0 Putative oxalocrotonate tautomerase enzyme DUF872 PF05915.12 OWF44292.1 - 3.1e-32 111.1 0.0 4.3e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.8 OWF44292.1 - 0.024 14.9 0.1 0.04 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF5381 PF17353.2 OWF44292.1 - 0.13 12.0 0.9 0.17 11.6 0.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5381) FixH PF05751.11 OWF44292.1 - 0.4 10.7 2.7 0.29 11.2 0.9 1.6 1 1 1 2 2 2 0 FixH IL17 PF06083.11 OWF44293.1 - 2.9e-13 50.1 7.5 5e-13 49.3 7.5 1.4 1 0 0 1 1 1 1 Interleukin-17 RRM_1 PF00076.22 OWF44294.1 - 2.9e-12 46.2 0.1 4.3e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_phi PF04931.13 OWF44295.1 - 5.7e-120 401.7 15.9 5.7e-120 401.7 15.9 2.2 2 0 0 2 2 2 1 DNA polymerase phi Cadherin PF00028.17 OWF44296.1 - 6.4e-98 321.4 34.0 3.1e-16 59.6 0.1 11.8 11 1 0 11 11 11 8 Cadherin domain Cadherin_C PF01049.17 OWF44296.1 - 6.3e-44 149.8 2.3 2e-43 148.2 2.3 1.9 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.24 OWF44296.1 - 2e-39 135.1 0.0 1.7e-24 86.8 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 OWF44296.1 - 4.1e-35 120.8 0.1 3.8e-23 82.1 0.0 3.2 3 0 0 3 3 2 2 Laminin G domain Cadherin_3 PF16184.5 OWF44296.1 - 3.8e-11 43.0 16.3 0.044 13.8 0.1 8.1 7 1 0 7 7 7 3 Cadherin-like EGF PF00008.27 OWF44296.1 - 2.8e-07 30.7 50.8 5.7e-06 26.5 9.4 5.0 4 0 0 4 4 4 3 EGF-like domain Cadherin_2 PF08266.12 OWF44296.1 - 3.1e-06 26.9 0.4 0.71 9.7 0.0 5.3 6 0 0 6 6 5 2 Cadherin-like RET_CLD1 PF17756.1 OWF44296.1 - 1.3e-05 25.5 0.0 0.00024 21.4 0.0 3.1 4 0 0 4 4 4 1 RET Cadherin like domain 1 Laminin_G_3 PF13385.6 OWF44296.1 - 5.2e-05 23.4 0.3 0.13 12.4 0.0 3.4 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 OWF44296.1 - 0.00047 20.3 8.7 0.00047 20.3 8.7 5.4 4 1 0 4 4 3 1 Calcium-binding EGF domain DUF1080 PF06439.11 OWF44296.1 - 0.045 13.9 0.0 1 9.5 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1080) hEGF PF12661.7 OWF44296.1 - 0.069 13.8 38.5 0.042 14.5 8.3 5.2 4 0 0 4 4 4 0 Human growth factor-like EGF ZirS_C PF16583.5 OWF44296.1 - 0.084 12.4 0.8 0.7 9.5 0.2 2.7 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain EGF_2 PF07974.13 OWF44296.1 - 0.85 10.0 47.4 3.2 8.2 6.7 4.0 3 0 0 3 3 3 0 EGF-like domain BRE1 PF08647.11 OWF44297.1 - 0.33 11.0 10.4 1 9.4 10.4 2.0 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 OWF44297.1 - 0.77 8.2 1.9 1.1 7.7 1.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Adeno_E3_CR2 PF02439.15 OWF44298.1 - 0.017 14.9 0.1 0.038 13.8 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4690 PF15756.5 OWF44298.1 - 0.08 13.6 2.0 0.19 12.4 0.0 2.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Rax2 PF12768.7 OWF44298.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Ank_2 PF12796.7 OWF44299.1 - 1.2e-85 282.2 12.5 3.5e-20 72.4 0.0 6.7 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF44299.1 - 1.9e-67 222.8 15.8 1e-13 51.4 0.0 10.7 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 OWF44299.1 - 4.9e-52 172.2 10.5 2.8e-05 24.4 0.0 13.4 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 OWF44299.1 - 7e-52 172.8 10.2 7e-10 39.0 0.0 10.3 3 2 7 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44299.1 - 6.6e-50 161.3 9.0 0.0018 18.6 0.0 13.3 13 0 0 13 13 13 10 Ankyrin repeat Death PF00531.22 OWF44299.1 - 8.1e-06 25.9 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Death domain AAA_33 PF13671.6 OWF44299.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OWF44299.1 - 0.015 15.6 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OWF44299.1 - 0.02 13.8 0.0 0.047 12.6 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KTI12 PF08433.10 OWF44299.1 - 0.022 14.2 0.0 0.06 12.8 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 OWF44299.1 - 0.044 14.3 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 OWF44299.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 OWF44299.1 - 0.61 9.6 2.4 0.89 9.0 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region Death PF00531.22 OWF44300.1 - 4.7e-08 33.1 0.0 7.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Death domain TLC PF03219.14 OWF44301.1 - 0.065 11.9 0.0 0.067 11.9 0.0 1.0 1 0 0 1 1 1 0 TLC ATP/ADP transporter APC_rep PF18797.1 OWF44302.1 - 7e-05 23.7 26.9 49 5.0 0.0 11.3 1 1 12 13 13 13 0 Adenomatous polyposis coli (APC) repeat Metallothio_Euk PF12749.7 OWF44302.1 - 0.00029 20.9 50.5 1.8e+04 -14.2 50.5 3.6 1 1 0 1 1 1 0 Eukaryotic metallothionein SNARE_assoc PF09335.11 OWF44302.1 - 0.0061 17.0 7.1 29 5.2 0.0 5.4 1 1 5 6 6 6 1 SNARE associated Golgi protein PIN_10 PF18478.1 OWF44302.1 - 0.75 10.0 8.6 78 3.6 0.1 5.9 4 3 3 7 7 7 0 PIN like domain DUF4938 PF16292.5 OWF44302.1 - 2.5 7.3 15.2 6.1 6.1 1.9 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4938) FmiP_Thoc5 PF09766.9 OWF44303.1 - 4.4e-128 427.6 10.6 4.4e-128 427.6 10.6 1.8 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 RWD PF05773.22 OWF44303.1 - 0.0088 16.3 0.0 0.0088 16.3 0.0 3.2 4 1 0 4 4 4 1 RWD domain BLOC1_2 PF10046.9 OWF44303.1 - 4.9 7.5 15.4 0.37 11.1 1.1 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-TRAF PF02176.18 OWF44304.1 - 6.9e-37 125.9 46.2 7.3e-17 61.8 7.5 5.2 3 2 2 5 5 5 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 OWF44304.1 - 9.2e-07 28.6 3.6 9.2e-07 28.6 3.6 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF44304.1 - 1.8e-05 24.6 2.5 1.8e-05 24.6 2.5 4.2 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF44304.1 - 2e-05 24.4 2.4 2e-05 24.4 2.4 4.4 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF44304.1 - 7.9e-05 22.6 5.9 7.9e-05 22.6 5.9 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 OWF44304.1 - 0.00025 21.4 42.6 0.045 14.2 6.1 5.0 1 1 5 6 6 6 4 TRAF-like zinc-finger zf-RING_2 PF13639.6 OWF44304.1 - 0.0069 16.7 6.8 0.0069 16.7 6.8 4.9 3 1 2 5 5 5 1 Ring finger domain zf-C2HC_2 PF13913.6 OWF44304.1 - 0.0088 15.9 0.4 0.0088 15.9 0.4 4.1 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf-Nse PF11789.8 OWF44304.1 - 7.4 6.5 14.6 0.044 13.6 2.7 3.4 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Pyr_redox_2 PF07992.14 OWF44305.1 - 3.3e-61 207.1 0.4 4.6e-61 206.6 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF44305.1 - 4.6e-18 65.6 5.8 6.3e-14 52.3 0.7 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OWF44305.1 - 8.3e-18 64.1 0.2 2e-17 62.9 0.2 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 OWF44305.1 - 3.8e-16 59.2 0.5 3.6e-11 42.9 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 OWF44305.1 - 3.4e-10 40.3 0.1 1.4e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.6 OWF44305.1 - 3.6e-07 30.1 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain HI0933_like PF03486.14 OWF44305.1 - 0.00022 20.0 0.0 0.63 8.7 0.0 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 OWF44305.1 - 0.0037 16.4 0.5 0.45 9.5 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OWF44305.1 - 0.005 17.0 2.3 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OWF44305.1 - 0.067 12.4 0.4 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 OWF44305.1 - 0.068 12.3 0.1 3.1 6.8 0.0 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 OWF44305.1 - 0.13 12.7 0.6 27 5.3 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Abhydrolase_3 PF07859.13 OWF44306.1 - 6.5e-53 179.7 0.0 1.3e-37 129.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF44306.1 - 3.7e-08 33.1 0.0 7.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 OWF44306.1 - 1.3e-06 27.6 0.4 4e-06 26.0 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OWF44306.1 - 5.9e-05 22.1 0.0 9.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 OWF44306.1 - 0.00016 20.4 0.1 0.00062 18.5 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 OWF44306.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme BAAT_C PF08840.11 OWF44306.1 - 0.052 13.5 0.2 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 OWF44306.1 - 0.12 12.1 0.0 0.74 9.6 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 OWF44306.1 - 0.2 11.1 0.2 2.1 7.8 0.1 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase RWD PF05773.22 OWF44307.1 - 4.8e-13 49.4 1.2 4.8e-13 49.4 1.2 1.8 2 0 0 2 2 2 1 RWD domain Foie-gras_1 PF11817.8 OWF44308.1 - 3.2e-65 220.3 0.1 5e-65 219.7 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 OWF44308.1 - 5.8e-16 58.4 0.6 8e-11 41.4 0.1 2.8 2 1 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 OWF44308.1 - 8e-10 38.6 0.1 6.4e-09 35.7 0.1 2.2 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 OWF44308.1 - 0.0013 18.5 0.0 0.0038 16.9 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Squash PF00299.18 OWF44308.1 - 0.071 13.1 5.1 0.23 11.5 5.1 1.9 1 0 0 1 1 1 0 Squash family serine protease inhibitor TPR_6 PF13174.6 OWF44308.1 - 1 10.1 4.2 7.6 7.4 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPH PF13868.6 OWF44309.1 - 2.3e-11 42.8 37.1 2.3e-11 42.8 37.1 2.2 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain USP8_interact PF08941.10 OWF44309.1 - 5 6.9 9.6 9.7 6.0 0.1 2.3 2 0 0 2 2 2 0 USP8 interacting TPH PF13868.6 OWF44310.1 - 1.5e-06 26.9 80.7 1.8e-06 26.7 80.7 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Evr1_Alr PF04777.13 OWF44311.1 - 0.73 10.3 4.8 1.2 9.6 0.0 3.6 4 0 0 4 4 4 0 Erv1 / Alr family Ribosomal_S9 PF00380.19 OWF44311.1 - 1.4 9.4 5.3 1.6 9.3 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S9/S16 DUF1168 PF06658.12 OWF44311.1 - 2.4 8.0 17.1 0.62 9.9 9.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF108 PF01958.18 OWF44312.1 - 1.3e-23 83.2 0.1 2e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 OWF44312.1 - 3e-10 40.8 0.0 5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 OWF44312.1 - 9.3e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OWF44312.1 - 0.0095 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OWF44312.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 OWF44312.1 - 0.12 12.7 0.0 4.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF4407 PF14362.6 OWF44314.1 - 0.018 14.4 31.3 0.038 13.3 14.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OWF44314.1 - 0.067 12.1 44.8 0.15 10.9 4.2 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 OWF44314.1 - 0.13 12.5 48.4 0.6 10.3 22.5 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fer2_BFD PF04324.15 OWF44314.1 - 0.18 12.2 1.6 27 5.2 0.1 3.1 2 1 0 2 2 2 0 BFD-like [2Fe-2S] binding domain SF-assemblin PF06705.11 OWF44314.1 - 0.36 10.2 31.6 0.59 9.4 25.8 2.7 1 1 1 2 2 2 0 SF-assemblin/beta giardin NADH_4Fe-4S PF10589.9 OWF44314.1 - 0.4 10.8 1.7 0.81 9.8 0.1 2.4 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Fez1 PF06818.15 OWF44314.1 - 0.93 9.9 39.6 1.4e+03 -0.5 39.0 2.6 1 1 0 1 1 1 0 Fez1 KASH_CCD PF14662.6 OWF44314.1 - 1.4 8.7 42.1 0.82 9.5 25.7 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 OWF44314.1 - 1.4 8.3 44.5 4.5 6.7 37.7 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3450 PF11932.8 OWF44314.1 - 2.5 7.3 33.8 0.76 9.0 10.0 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) HycH PF07450.11 OWF44314.1 - 5.5 7.4 8.7 2.3 8.6 5.0 2.2 1 1 1 2 2 2 0 Formate hydrogenlyase maturation protein HycH NPV_P10 PF05531.12 OWF44314.1 - 5.6 7.5 17.4 13 6.3 1.2 4.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DHR10 PF18595.1 OWF44314.1 - 5.8 7.0 45.4 0.96 9.5 5.0 3.5 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain HIP1_clath_bdg PF16515.5 OWF44314.1 - 6.5 7.4 45.0 0.11 13.1 4.6 4.4 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 OWF44314.1 - 7.3 7.1 53.8 0.21 12.1 14.6 3.7 1 1 3 4 4 4 0 Apg6 coiled-coil region NACHT PF05729.12 OWF44315.1 - 9.6e-09 35.4 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OWF44315.1 - 1.1e-08 35.7 0.2 7.1e-08 33.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF4062 PF13271.6 OWF44315.1 - 1e-07 32.2 0.0 3.5e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) WD40 PF00400.32 OWF44315.1 - 1.6e-07 31.9 3.6 0.067 14.1 0.3 5.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ATPase_2 PF01637.18 OWF44315.1 - 2.4e-05 24.4 0.0 6.7e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ANAPC4_WD40 PF12894.7 OWF44315.1 - 0.00048 20.4 0.6 6.4 7.1 0.0 5.6 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 OWF44315.1 - 0.00061 20.1 0.0 0.0021 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OWF44315.1 - 0.0091 16.4 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OWF44315.1 - 0.017 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ResIII PF04851.15 OWF44315.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OWF44315.1 - 0.12 12.1 1.8 0.91 9.2 0.0 2.9 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase APAF1_C PF17908.1 OWF44315.1 - 0.12 12.4 0.2 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 APAF-1 helical domain BESS PF02944.20 OWF44315.1 - 0.27 11.1 2.0 0.33 10.8 0.2 2.2 2 0 0 2 2 2 0 BESS motif AAA_16 PF13191.6 OWF44316.1 - 1.6e-08 35.1 0.2 1e-07 32.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OWF44316.1 - 5.1e-08 33.0 0.1 1.1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 OWF44316.1 - 1.3e-07 32.2 2.9 0.05 14.5 0.2 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4062 PF13271.6 OWF44316.1 - 2e-07 31.3 0.1 1.4e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) ATPase_2 PF01637.18 OWF44316.1 - 4.3e-05 23.6 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ANAPC4_WD40 PF12894.7 OWF44316.1 - 0.0003 21.0 0.7 6.8 7.1 0.0 5.7 6 1 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 OWF44316.1 - 0.0011 19.5 0.0 0.0052 17.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF44316.1 - 0.0032 17.7 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OWF44316.1 - 0.033 14.2 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OWF44316.1 - 0.098 12.4 1.9 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APAF1_C PF17908.1 OWF44316.1 - 0.13 12.2 0.1 1.2 9.2 0.0 2.6 3 0 0 3 3 3 0 APAF-1 helical domain BESS PF02944.20 OWF44316.1 - 0.28 11.1 2.5 0.22 11.4 0.3 2.1 2 0 0 2 2 2 0 BESS motif LRR_5 PF13306.6 OWF44317.1 - 2.2e-15 56.7 4.8 4.7e-05 23.4 0.5 4.2 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) DUF3931 PF13082.6 OWF44317.1 - 1.9e-05 24.7 0.0 21 5.4 0.0 6.8 2 1 5 9 9 9 1 Protein of unknown function (DUF3931) Phage_FRD3 PF05798.11 OWF44317.1 - 0.082 13.2 2.2 16 5.9 0.0 4.8 5 1 0 6 6 6 0 Bacteriophage FRD3 protein PH PF00169.29 OWF44318.1 - 2.5e-13 50.4 1.8 4.6e-13 49.6 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OWF44318.1 - 3.8e-05 24.0 6.0 0.00014 22.3 1.0 3.8 2 2 1 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 OWF44318.1 - 0.0012 18.9 0.2 0.0044 17.1 0.2 2.0 1 0 0 1 1 1 1 PH domain tRNA-synt_1e PF01406.19 OWF44318.1 - 0.018 14.4 0.6 0.018 14.4 0.6 2.3 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain BCAS3 PF12490.8 OWF44319.1 - 6e-31 107.8 0.1 1.2e-30 106.9 0.1 1.4 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 OWF44319.1 - 2.8 8.9 9.1 22 6.1 0.3 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat T-box PF00907.22 OWF44320.1 - 2.1e-84 282.3 0.3 3e-84 281.8 0.3 1.2 1 0 0 1 1 1 1 T-box T-box PF00907.22 OWF44321.1 - 2e-83 279.2 0.4 2.9e-83 278.7 0.4 1.3 1 0 0 1 1 1 1 T-box MutS_V PF00488.21 OWF44324.1 - 1.4e-07 31.7 7.4 0.33 11.0 0.2 5.1 1 1 4 5 5 5 3 MutS domain V RLAN PF14401.6 OWF44324.1 - 0.004 16.8 5.1 1.6 8.4 0.1 4.0 1 1 3 4 4 4 2 RimK-like ATPgrasp N-terminal domain DUF2140 PF09911.9 OWF44324.1 - 0.017 14.7 1.5 3.3 7.2 0.2 3.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Yuri_gagarin PF15934.5 OWF44324.1 - 6.6 6.5 25.4 22 4.8 0.4 6.7 2 1 5 7 7 7 0 Yuri gagarin Cadherin-like PF12733.7 OWF44324.1 - 7.2 7.2 18.7 1.8e+04 -5.7 18.8 5.2 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain DUF5401 PF17380.2 OWF44324.1 - 8.2 4.4 14.5 6.4 4.7 2.1 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5401) Helicase_C_2 PF13307.6 OWF44325.1 - 2.5e-53 180.8 0.0 1.7e-52 178.1 0.0 2.3 1 1 1 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OWF44325.1 - 1.6e-46 158.1 1.2 2.3e-46 157.6 0.0 2.0 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 OWF44325.1 - 4.5e-06 26.6 0.1 0.013 15.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 OWF44325.1 - 6.5e-05 23.0 0.0 0.07 13.1 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Acyl-CoA_dh_1 PF00441.24 OWF44326.1 - 4.8e-14 52.8 0.3 7.7e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OWF44326.1 - 5.1e-14 52.2 0.0 8.3e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF44326.1 - 3.2e-07 30.7 0.2 5.5e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OWF44326.1 - 5.7e-06 27.0 0.0 1e-05 26.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 OWF44326.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal APH PF01636.23 OWF44327.1 - 3.9e-48 164.5 0.0 6.2e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 OWF44327.1 - 4e-36 124.5 5.0 4.7e-36 124.3 3.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OWF44327.1 - 1.2e-17 63.9 0.0 2.5e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OWF44327.1 - 9.3e-17 61.7 0.1 7.7e-16 58.8 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HAD_2 PF13419.6 OWF44327.1 - 9.5e-13 48.6 0.0 2.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acyl-CoA_dh_2 PF08028.11 OWF44327.1 - 1.3e-12 48.1 2.4 2.3e-12 47.3 2.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Hydrolase PF00702.26 OWF44327.1 - 7.2e-07 29.7 0.0 3.5e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EcKinase PF02958.20 OWF44327.1 - 0.00021 20.7 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 OWF44327.1 - 0.019 14.6 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Hydrolase_like PF13242.6 OWF44327.1 - 0.054 13.6 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 HAD-hyrolase-like Methyltransf_21 PF05050.12 OWF44328.1 - 9.2e-07 29.0 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain PrmA PF06325.13 OWF44329.1 - 3.4e-11 43.1 0.3 4.6e-11 42.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OWF44329.1 - 5.5e-06 26.0 0.1 1.7e-05 24.4 0.2 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OWF44329.1 - 6.6e-05 22.7 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OWF44329.1 - 0.00023 21.8 0.6 0.00046 20.8 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 OWF44329.1 - 0.0011 18.8 0.1 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.12 OWF44329.1 - 0.059 14.0 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 OWF44329.1 - 0.068 12.5 0.4 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain TRM PF02005.16 OWF44329.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DNA_methylase PF00145.17 OWF44329.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_12 PF08242.12 OWF44329.1 - 0.15 12.8 0.1 0.25 12.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OWF44329.1 - 0.32 10.3 0.0 0.32 10.3 0.0 2.0 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase SAA PF00277.18 OWF44330.1 - 5e-46 155.4 9.3 5.9e-46 155.1 9.3 1.1 1 0 0 1 1 1 1 Serum amyloid A protein Arm PF00514.23 OWF44331.1 - 4.3e-11 42.5 0.9 0.0012 18.8 0.0 6.4 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat BTB PF00651.31 OWF44331.1 - 7.5e-07 29.4 0.0 1.9e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain HEAT_2 PF13646.6 OWF44331.1 - 0.00015 22.1 0.1 0.0067 16.8 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats RICTOR_N PF14664.6 OWF44331.1 - 0.0032 16.5 0.1 0.18 10.8 0.1 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term HEAT PF02985.22 OWF44331.1 - 0.14 12.5 2.8 6.8 7.2 0.2 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 OWF44331.1 - 0.3 11.7 0.7 8 7.1 0.1 3.1 3 0 0 3 3 3 0 HEAT-like repeat Phospholip_A2_2 PF05826.12 OWF44333.1 - 6.4e-34 116.1 2.0 1.4e-33 114.9 2.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 OWF44333.1 - 2.4 8.7 12.2 6.3 7.3 7.5 2.7 2 1 0 2 2 2 0 Phospholipase A2 Cyt-b5 PF00173.28 OWF44334.1 - 1.8e-09 37.6 0.5 3.9e-09 36.5 0.5 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CN_hydrolase PF00795.22 OWF44335.1 - 1.1e-12 47.8 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MIF PF01187.18 OWF44336.1 - 2.7e-39 134.0 0.0 3.4e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Macrophage migration inhibitory factor (MIF) GAPES4 PF17157.4 OWF44337.1 - 0.00016 22.0 25.2 3.7 8.0 0.5 5.4 1 1 6 7 7 7 7 Gammaproteobacterial periplasmic sensor domain Chordopox_G3 PF06129.12 OWF44337.1 - 9.5 7.0 28.5 55 4.5 3.6 4.3 1 1 1 2 2 2 0 Chordopoxvirus G3 protein Pkinase PF00069.25 OWF44338.1 - 1.3e-59 201.7 0.0 3.9e-59 200.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF44338.1 - 1.1e-19 70.7 0.0 1.9e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF44338.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PRP8_domainIV PF12134.8 OWF44338.1 - 0.078 12.6 0.1 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 PRP8 domain IV core Kinase-like PF14531.6 OWF44338.1 - 0.085 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 OWF44338.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UCH PF00443.29 OWF44339.1 - 8.1e-34 117.3 0.0 1.2e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF44339.1 - 2.9e-14 53.4 0.0 5.9e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Guanylate_cyc PF00211.20 OWF44340.1 - 1.5e-64 217.0 0.0 3.3e-64 215.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF44340.1 - 2.8e-39 135.0 0.0 4.1e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF44340.1 - 6.2e-32 111.0 0.0 2.2e-31 109.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain ANF_receptor PF01094.28 OWF44340.1 - 8.4e-27 94.2 0.9 1.2e-26 93.7 0.9 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 OWF44340.1 - 6.1e-06 25.8 1.0 1e-05 25.1 1.0 1.3 1 0 0 1 1 1 1 Heme NO binding associated Syndecan PF01034.20 OWF44340.1 - 0.0023 17.8 0.2 0.0065 16.4 0.2 1.7 1 0 0 1 1 1 1 Syndecan domain Insulin_TMD PF17870.1 OWF44340.1 - 0.0031 17.5 0.4 0.0084 16.2 0.0 1.9 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment SKG6 PF08693.10 OWF44340.1 - 0.0086 15.5 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Acetyltransf_15 PF17013.5 OWF44340.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Putative acetyl-transferase Mab-21 PF03281.14 OWF44341.1 - 1.7e-24 86.7 2.4 3.3e-24 85.7 2.4 1.4 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF44341.1 - 0.007 16.6 1.0 0.11 12.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat NTP_transf_2 PF01909.23 OWF44341.1 - 0.044 14.1 0.0 1.2 9.5 0.0 3.2 4 0 0 4 4 4 0 Nucleotidyltransferase domain TPR_2 PF07719.17 OWF44341.1 - 0.063 13.4 4.5 2.1 8.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HI0933_like PF03486.14 OWF44341.1 - 0.093 11.4 0.1 9.9 4.7 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein TPR_8 PF13181.6 OWF44341.1 - 0.13 12.5 0.4 10 6.6 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ran_BP1 PF00638.18 OWF44342.1 - 7.7e-50 168.2 0.0 1.3e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain 7tm_1 PF00001.21 OWF44344.1 - 0.0072 15.7 14.2 0.012 14.9 14.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_M56 PF05569.11 OWF44344.1 - 0.018 14.3 0.1 0.039 13.1 0.1 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 FixH PF05751.11 OWF44344.1 - 0.16 12.0 1.4 0.38 10.8 1.4 1.6 1 0 0 1 1 1 0 FixH DUF3377 PF11857.8 OWF44344.1 - 3.9 7.5 6.4 26 4.8 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3377) DUF3105 PF11303.8 OWF44345.1 - 5.2e-29 101.0 0.1 7.7e-29 100.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) Pkinase PF00069.25 OWF44346.1 - 1.3e-60 205.0 0.0 1.7e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF44346.1 - 5.1e-30 104.6 0.1 6.6e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF44346.1 - 7.9e-07 28.7 0.1 4.1e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF44346.1 - 0.0011 17.8 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OWF44346.1 - 0.0039 16.8 0.7 2.6 7.6 0.1 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OWF44346.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain COX6A PF02046.15 OWF44347.1 - 3.7e-05 24.2 0.8 4.9e-05 23.8 0.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa GATase PF00117.28 OWF44347.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Cu2_monoox_C PF03712.15 OWF44348.1 - 2.4e-24 85.6 0.1 4.4e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain 7tm_1 PF00001.21 OWF44349.1 - 2.1e-20 73.2 24.9 2.9e-20 72.7 24.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 OWF44349.1 - 0.0017 18.4 5.6 0.62 10.2 0.9 2.8 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 C-term CitMHS PF03600.16 OWF44349.1 - 0.0086 15.3 15.2 0.012 14.9 15.2 1.2 1 0 0 1 1 1 1 Citrate transporter PIG-F PF06699.11 OWF44349.1 - 9.9 6.3 14.7 0.17 12.0 1.2 2.7 1 1 1 2 2 2 0 GPI biosynthesis protein family Pig-F Spectrin PF00435.21 OWF44350.1 - 1.1e-09 38.6 28.2 0.00016 22.1 0.3 7.2 7 1 0 7 7 7 3 Spectrin repeat Kinesin_assoc PF16183.5 OWF44350.1 - 0.039 14.1 1.4 2.4 8.3 0.1 3.0 2 1 0 2 2 2 0 Kinesin-associated Nup54_57_C PF18570.1 OWF44350.1 - 0.96 9.1 6.2 0.12 12.0 0.7 2.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain AAA_16 PF13191.6 OWF44350.1 - 1 9.7 7.9 1.7 9.0 0.5 3.4 4 0 0 4 4 4 0 AAA ATPase domain CSN8_PSD8_EIF3K PF10075.9 OWF44351.1 - 8.2e-32 110.2 0.0 1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OWF44351.1 - 0.092 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP family UQ_con PF00179.26 OWF44352.1 - 3.3e-31 107.8 0.0 4.1e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF44352.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B ESCRT-II PF05871.12 OWF44353.1 - 4.4e-53 179.3 1.4 5.5e-53 179.0 1.4 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit DUF2555 PF10742.9 OWF44353.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Pkinase_Tyr PF07714.17 OWF44354.1 - 3.9e-36 124.7 0.1 6.1e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF44354.1 - 8e-35 120.5 0.0 1.2e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 OWF44354.1 - 4.8e-13 48.3 0.1 9.3e-13 47.4 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 OWF44354.1 - 0.00018 20.4 0.2 0.00058 18.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OWF44354.1 - 0.0014 18.6 0.1 0.0048 16.9 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Activin_recp PF01064.23 OWF44354.1 - 0.0036 18.4 9.4 0.0036 18.4 9.4 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain Haspin_kinase PF12330.8 OWF44354.1 - 0.13 11.2 0.0 0.63 8.9 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Toxin_3 PF00537.18 OWF44354.1 - 0.23 11.7 6.5 0.24 11.6 1.7 2.8 2 0 0 2 2 2 0 Scorpion toxin-like domain Ldl_recept_a PF00057.18 OWF44355.1 - 1.5e-05 25.1 8.7 1.5e-05 25.1 8.7 2.5 2 1 0 2 2 2 1 Low-density lipoprotein receptor domain class A LapA_dom PF06305.11 OWF44355.1 - 0.00043 20.0 0.0 0.00062 19.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Insulin_TMD PF17870.1 OWF44355.1 - 0.0017 18.4 0.1 0.0025 17.8 0.1 1.2 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 OWF44355.1 - 0.0036 18.1 0.2 0.0046 17.8 0.2 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OWF44355.1 - 0.0053 17.5 0.1 0.0065 17.2 0.1 1.2 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal NicO PF03824.16 OWF44355.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF4736 PF15883.5 OWF44355.1 - 0.013 15.3 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) DAG1 PF05454.11 OWF44355.1 - 0.039 13.3 2.0 0.06 12.7 2.0 1.3 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 OWF44355.1 - 0.06 13.3 0.1 0.071 13.0 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 OWF44355.1 - 0.061 13.2 1.1 0.074 13.0 1.1 1.2 1 0 0 1 1 1 0 Transmembrane 52 Filamin PF00630.19 OWF44356.1 - 1.3e-10 42.0 0.0 3.7e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-RING_UBOX PF13445.6 OWF44356.1 - 2e-05 24.5 8.1 2e-05 24.5 8.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF44356.1 - 0.001 18.9 6.1 0.001 18.9 6.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF44356.1 - 0.0023 17.7 7.6 0.0023 17.7 7.6 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF44356.1 - 0.0071 16.5 9.1 0.0071 16.5 9.1 3.7 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF44356.1 - 0.0073 16.2 4.1 0.0073 16.2 4.1 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF44356.1 - 0.013 15.7 5.8 0.013 15.7 5.8 2.9 3 0 0 3 3 3 0 B-box zinc finger PP2C_C PF07830.13 OWF44356.1 - 0.08 13.4 1.4 3.9 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Invasin_D3 PF09134.10 OWF44356.1 - 0.1 12.9 2.1 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Invasin, domain 3 DUF4573 PF15140.6 OWF44357.1 - 0.00069 19.4 19.3 0.14 11.9 0.8 4.2 1 1 3 4 4 4 4 Domain of unknown function (DUF4573) CagY_I PF14585.6 OWF44357.1 - 0.38 10.9 14.0 48 4.2 0.0 7.2 4 3 4 10 10 10 0 CagY type 1 repeat MKLP1_Arf_bdg PF16540.5 OWF44357.1 - 1.1 9.3 6.4 6.8 6.8 0.1 4.4 3 2 0 4 4 4 0 Arf6-interacting domain of mitotic kinesin-like protein 1 PTase_Orf2 PF11468.8 OWF44358.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 RACo_linker PF17650.1 OWF44358.1 - 0.19 11.6 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 RACo linker region Ank_2 PF12796.7 OWF44359.1 - 2.7e-38 130.4 12.1 1.8e-08 34.9 0.1 10.5 4 2 6 11 11 11 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF44359.1 - 1.7e-28 98.6 8.1 0.34 11.5 0.0 14.0 10 3 4 15 15 13 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF44359.1 - 1.1e-23 82.5 11.6 0.042 14.3 0.0 12.1 13 0 0 13 13 11 5 Ankyrin repeat Ank_5 PF13857.6 OWF44359.1 - 2.5e-23 81.8 1.9 1e-07 32.1 0.0 10.5 10 2 0 10 10 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44359.1 - 1e-19 68.5 4.7 0.36 11.5 0.0 14.9 18 0 0 18 18 13 4 Ankyrin repeat HEPN_DZIP3 PF18738.1 OWF44359.1 - 8.5e-12 45.0 1.6 2.3e-11 43.6 1.6 1.8 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN T2SSE PF00437.20 OWF44359.1 - 0.0012 17.9 0.0 0.0034 16.5 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein APS_kinase PF01583.20 OWF44359.1 - 0.0018 18.2 0.0 0.0058 16.5 0.0 1.9 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_7 PF12775.7 OWF44359.1 - 0.0092 15.5 0.4 0.056 13.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 OWF44359.1 - 0.015 15.7 0.1 0.11 12.9 0.0 2.6 2 0 0 2 2 1 0 AAA ATPase domain NACHT PF05729.12 OWF44359.1 - 0.016 15.1 0.6 0.35 10.8 0.1 2.8 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 OWF44359.1 - 0.019 14.4 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 OWF44359.1 - 0.02 14.9 3.2 0.037 14.0 0.2 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 OWF44359.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 OWF44359.1 - 0.032 14.4 0.3 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 OWF44359.1 - 0.033 14.5 0.1 2.3 8.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain MIT PF04212.18 OWF44359.1 - 0.042 13.9 0.3 0.17 11.9 0.3 2.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain ATPase PF06745.13 OWF44359.1 - 0.065 12.6 1.9 0.13 11.6 0.1 2.5 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 OWF44359.1 - 0.069 13.2 1.1 0.56 10.3 0.2 3.3 2 1 0 2 2 1 0 AAA domain PhoH PF02562.16 OWF44359.1 - 0.071 12.6 0.1 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein HEPN_Swt1 PF18731.1 OWF44359.1 - 0.073 13.4 0.4 0.32 11.4 0.1 2.4 2 0 0 2 2 1 0 Swt1-like HEPN AAA_29 PF13555.6 OWF44359.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain LPP PF04728.13 OWF44359.1 - 0.13 12.6 1.8 0.8 10.1 1.8 2.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Ank_2 PF12796.7 OWF44360.1 - 9.2e-32 109.5 9.6 7.4e-06 26.5 0.0 8.4 3 2 4 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF44360.1 - 7.9e-16 58.2 12.3 0.0023 18.5 0.0 11.2 7 4 6 13 13 12 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF44360.1 - 1.1e-12 47.8 1.6 0.17 12.2 0.0 7.6 7 1 1 8 8 7 4 Ankyrin repeats (many copies) HEPN_DZIP3 PF18738.1 OWF44360.1 - 1.4e-11 44.3 0.0 4.4e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN Ank PF00023.30 OWF44360.1 - 1e-09 38.4 8.7 3 8.4 0.0 10.2 10 0 0 10 10 10 1 Ankyrin repeat Ank_3 PF13606.6 OWF44360.1 - 1.1e-09 37.6 8.9 6.6 7.6 0.0 10.6 11 0 0 11 11 9 2 Ankyrin repeat SlyX PF04102.12 OWF44360.1 - 0.008 16.8 0.8 0.008 16.8 0.8 3.0 3 0 0 3 3 3 1 SlyX FAM150 PF15129.6 OWF44360.1 - 0.02 15.0 0.2 0.085 13.0 0.2 2.1 1 0 0 1 1 1 0 FAM150 family SnoaL_4 PF13577.6 OWF44360.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain DNA_pol3_delta2 PF13177.6 OWF44360.1 - 0.039 13.7 3.4 0.055 13.3 0.8 2.3 2 0 0 2 2 2 0 DNA polymerase III, delta subunit DUF3288 PF11691.8 OWF44360.1 - 0.099 12.7 0.1 3.4 7.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) PhoH PF02562.16 OWF44360.1 - 0.14 11.6 0.2 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF2652 PF10851.8 OWF44360.1 - 0.27 11.4 1.8 2.9 8.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2652) zf-C3HC4_3 PF13920.6 OWF44361.1 - 2.1e-07 30.7 13.3 3.5e-07 30.0 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44361.1 - 0.0065 16.3 14.1 0.012 15.4 14.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OWF44362.1 - 1.3e-07 31.3 15.0 2.1e-07 30.7 15.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44362.1 - 0.0087 15.9 13.5 0.015 15.2 13.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Vps39_2 PF10367.9 OWF44362.1 - 0.016 15.6 2.7 0.021 15.2 0.6 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Hydrolase PF00702.26 OWF44362.1 - 0.052 13.8 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ThrE PF06738.12 OWF44362.1 - 0.25 10.7 0.1 0.38 10.1 0.1 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter BIR PF00653.21 OWF44363.1 - 3.5e-30 104.5 11.8 4.6e-17 62.4 0.1 3.3 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF44363.1 - 2.6e-10 40.0 14.8 3.2e-10 39.7 12.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44363.1 - 4.9e-05 23.1 12.0 0.00017 21.4 12.0 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF44363.1 - 1.5 8.8 10.4 5.8 7.0 10.4 2.1 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 OWF44363.1 - 1.5 9.2 12.5 6.1 7.3 12.5 2.2 1 0 0 1 1 1 0 Ring finger domain zf-ribbon_3 PF13248.6 OWF44363.1 - 4.1 7.0 9.0 1.8 8.1 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain LIM PF00412.22 OWF44364.1 - 2.4e-64 213.4 90.6 2e-13 50.3 7.6 6.4 6 1 0 6 6 6 6 LIM domain PET PF06297.14 OWF44364.1 - 2.7e-16 59.6 0.0 6.1e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 PET Domain TMPIT PF07851.13 OWF44365.1 - 9.5 5.4 21.8 6.5 5.9 0.5 5.4 1 1 3 5 5 5 0 TMPIT-like protein Chitin_synth_2 PF03142.15 OWF44366.1 - 7.2e-30 104.1 1.2 2.4e-26 92.5 0.3 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF44366.1 - 1.5e-13 51.1 1.9 1.5e-13 51.1 1.9 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF44366.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF44366.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 WBP-1 PF11669.8 OWF44366.1 - 0.097 13.3 0.2 1 10.0 0.0 2.9 2 0 0 2 2 2 0 WW domain-binding protein 1 Isochorismatase PF00857.20 OWF44367.1 - 3.5e-26 92.5 0.1 7.8e-26 91.3 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family Chitin_synth_2 PF03142.15 OWF44368.1 - 1.5e-29 103.0 3.6 3.2e-26 92.0 0.9 2.5 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF44368.1 - 1.6e-10 41.2 2.1 1.6e-10 41.2 2.1 3.3 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF44368.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF44368.1 - 0.0089 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Imm51 PF15595.6 OWF44368.1 - 0.065 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 51 ADAM_CR_2 PF17771.1 OWF44369.1 - 9.5e-18 64.5 7.9 9.5e-18 64.5 7.9 3.2 2 1 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF44369.1 - 9.9e-17 61.7 1.5 9.9e-17 61.7 1.5 3.7 2 1 1 4 4 4 1 Metallo-peptidase family M12 Reprolysin PF01421.19 OWF44369.1 - 1.4e-16 61.0 0.0 3.9e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 OWF44369.1 - 9.7e-12 45.5 0.1 9.7e-12 45.5 0.1 3.7 4 0 0 4 4 4 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF44369.1 - 1.1e-09 38.5 0.7 8e-09 35.7 0.7 2.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF44369.1 - 1.1e-08 34.9 6.9 4e-08 33.1 3.9 3.1 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Shisa PF13908.6 OWF44369.1 - 0.0025 18.1 2.6 0.0025 18.1 2.6 7.6 2 1 4 6 6 6 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OWF44369.1 - 0.011 15.6 5.1 0.011 15.6 5.1 7.2 1 1 3 4 4 4 0 TMEM154 protein family Peptidase_M10 PF00413.24 OWF44369.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Matrixin GRASP55_65 PF04495.14 OWF44370.1 - 4.5e-76 253.8 0.0 4.7e-55 185.7 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 OWF44370.1 - 4.2e-09 36.6 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OWF44370.1 - 3.5e-07 30.0 0.0 0.027 14.3 0.0 2.7 2 1 0 2 2 2 2 PDZ domain Acetyltransf_18 PF18014.1 OWF44372.1 - 1.9e-13 50.4 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RcnB PF11776.8 OWF44372.1 - 0.017 15.1 0.1 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator Acetyltransf_10 PF13673.7 OWF44372.1 - 0.052 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GlcV_C_terminal PF17847.1 OWF44374.1 - 0.0024 18.3 9.4 3.4 8.2 0.1 4.8 1 1 4 5 5 5 4 Glucose ABC transporter C-terminal domain DUF1943 PF09172.11 OWF44374.1 - 0.3 10.3 17.6 2.6 7.2 7.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) Nucleoporin_FG2 PF15967.5 OWF44374.1 - 1 7.8 15.4 1.3 7.5 15.4 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region Glyco_transf_10 PF00852.19 OWF44375.1 - 2.6e-47 160.8 1.1 4.1e-47 160.2 1.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF44375.1 - 4.2e-18 65.8 0.5 1.2e-17 64.3 0.1 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 OWF44375.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 GSHPx PF00255.19 OWF44376.1 - 8.6e-05 22.1 0.1 0.00015 21.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione peroxidase L6_membrane PF05805.12 OWF44376.1 - 0.037 13.6 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 L6 membrane protein GSHPx PF00255.19 OWF44377.1 - 0.0074 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase MFS_1 PF07690.16 OWF44378.1 - 3.3e-62 210.5 23.7 3.9e-62 210.2 23.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF44378.1 - 4.2e-11 42.4 20.6 2.7e-10 39.7 20.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 OWF44378.1 - 7.3e-05 22.2 3.5 7.3e-05 22.2 3.5 2.1 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 OWF44378.1 - 0.0041 15.7 1.4 0.0041 15.7 1.4 3.6 2 2 1 3 3 3 1 MFS/sugar transport protein ParA PF10609.9 OWF44380.1 - 2.6e-45 154.8 0.0 3e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 OWF44380.1 - 0.005 16.3 0.0 0.0058 16.1 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PhnA_Zn_Ribbon PF08274.12 OWF44380.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon ParA PF10609.9 OWF44381.1 - 1.4e-38 132.8 0.6 1.7e-38 132.5 0.6 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OWF44381.1 - 8.1e-09 35.6 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OWF44381.1 - 7.3e-07 29.3 0.1 9.3e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 OWF44381.1 - 2.6e-05 23.6 0.0 3.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OWF44381.1 - 0.00056 19.2 0.2 0.00086 18.6 0.2 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 OWF44381.1 - 0.0038 16.7 0.2 0.006 16.1 0.0 1.4 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 OWF44381.1 - 0.0076 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain VirC1 PF07015.11 OWF44381.1 - 0.043 13.1 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein NACHT PF05729.12 OWF44381.1 - 0.25 11.2 0.6 0.5 10.3 0.2 1.6 2 0 0 2 2 2 0 NACHT domain 7tm_1 PF00001.21 OWF44383.1 - 9.9e-48 162.7 12.0 1.3e-47 162.4 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44383.1 - 2.8e-11 43.6 9.6 2.8e-11 43.6 9.6 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF44383.1 - 1.1e-08 34.8 13.9 1.6e-08 34.3 13.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Hyphal_reg_CWP PF11765.8 OWF44384.1 - 0.077 11.9 0.9 0.16 10.9 0.6 1.5 1 1 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal KH_5 PF13184.6 OWF44384.1 - 0.17 12.0 1.2 13 6.0 0.1 2.5 2 1 0 2 2 2 0 NusA-like KH domain Lipase_GDSL_2 PF13472.6 OWF44386.1 - 0.0013 19.2 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TMF_TATA_bd PF12325.8 OWF44389.1 - 0.00096 19.4 4.5 0.0019 18.4 4.5 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding VPS38 PF17649.1 OWF44389.1 - 0.0026 16.7 5.8 0.0053 15.7 5.8 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Speriolin_N PF15058.6 OWF44389.1 - 0.0031 17.6 0.1 0.005 17.0 0.1 1.3 1 0 0 1 1 1 1 Speriolin N terminus FlaC_arch PF05377.11 OWF44389.1 - 0.008 16.6 3.4 0.008 16.6 3.4 2.4 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 OWF44389.1 - 0.0082 16.4 5.7 0.019 15.3 5.0 2.0 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 OWF44389.1 - 0.011 15.8 4.8 0.095 12.8 5.6 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4455 PF14643.6 OWF44389.1 - 0.017 13.8 4.6 0.021 13.5 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Shugoshin_N PF07558.11 OWF44389.1 - 0.02 14.8 7.5 0.054 13.4 3.8 2.9 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF3450 PF11932.8 OWF44389.1 - 0.023 14.0 2.6 0.036 13.4 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 OWF44389.1 - 0.024 14.4 8.8 0.041 13.6 8.8 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 MbeD_MobD PF04899.12 OWF44389.1 - 0.024 14.8 0.9 0.06 13.5 1.0 1.6 1 1 0 1 1 1 0 MbeD/MobD like HAUS-augmin3 PF14932.6 OWF44389.1 - 0.024 14.2 3.6 0.039 13.5 3.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 XLF PF09302.11 OWF44389.1 - 0.025 14.8 3.7 0.072 13.3 3.8 1.7 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component BshC PF10079.9 OWF44389.1 - 0.025 13.4 2.6 0.035 12.9 2.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC UPF0242 PF06785.11 OWF44389.1 - 0.035 14.2 5.9 0.069 13.2 5.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AKNA PF12443.8 OWF44389.1 - 0.054 14.2 1.8 0.054 14.2 1.8 2.2 2 1 0 2 2 1 0 AT-hook-containing transcription factor DUF2207 PF09972.9 OWF44389.1 - 0.058 12.1 1.1 0.099 11.4 1.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4407 PF14362.6 OWF44389.1 - 0.098 12.0 1.0 0.14 11.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 OWF44389.1 - 0.11 12.4 11.8 0.28 11.1 4.8 2.7 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3552 PF12072.8 OWF44389.1 - 0.13 11.7 5.7 0.25 10.7 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SlyX PF04102.12 OWF44389.1 - 0.13 12.9 1.4 0.31 11.7 1.4 1.7 1 0 0 1 1 1 0 SlyX NYD-SP28 PF14772.6 OWF44389.1 - 0.23 11.5 6.4 0.16 12.0 3.5 2.0 1 1 1 2 2 2 0 Sperm tail ZapB PF06005.12 OWF44389.1 - 0.23 11.9 9.0 0.14 12.7 6.0 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 OWF44389.1 - 0.24 11.4 9.4 0.32 11.1 6.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0449 PF15136.6 OWF44389.1 - 0.27 11.7 5.7 0.96 10.0 5.7 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 PUFD PF16553.5 OWF44389.1 - 0.56 10.3 4.0 0.7 10.0 0.4 2.1 1 1 1 2 2 2 0 BCORL-PCGF1-binding domain Lectin_N PF03954.14 OWF44389.1 - 0.99 9.2 6.4 0.74 9.6 4.7 1.6 2 0 0 2 2 1 0 Hepatic lectin, N-terminal domain TMF_DNA_bd PF12329.8 OWF44389.1 - 1 9.4 16.5 0.055 13.5 9.6 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 OWF44389.1 - 1.2 9.0 11.2 0.1 12.4 5.6 2.2 2 1 0 2 2 1 0 Septum formation initiator Syntaxin_2 PF14523.6 OWF44389.1 - 1.5 9.3 12.1 0.27 11.6 3.4 3.0 1 1 2 3 3 3 0 Syntaxin-like protein Cnn_1N PF07989.11 OWF44389.1 - 1.6 8.9 10.3 0.26 11.5 6.0 1.9 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 DUF4446 PF14584.6 OWF44389.1 - 1.7 8.6 8.0 2.5 8.0 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Swi5 PF07061.11 OWF44389.1 - 1.9 8.7 7.5 23 5.2 1.2 3.3 2 1 1 3 3 3 0 Swi5 TolA_bind_tri PF16331.5 OWF44389.1 - 3.8 7.7 7.8 0.51 10.4 3.0 1.8 1 1 1 2 2 2 0 TolA binding protein trimerisation YabA PF06156.13 OWF44389.1 - 4.7 7.9 8.1 19 5.9 7.9 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Csm1_N PF18504.1 OWF44389.1 - 5 7.5 10.9 0.83 10.0 5.5 2.3 2 1 1 3 3 2 0 Csm1 N-terminal domain GAT PF03127.14 OWF44389.1 - 6.7 7.1 10.0 11 6.4 0.5 2.6 1 1 1 2 2 2 0 GAT domain bZIP_2 PF07716.15 OWF44389.1 - 7.8 6.7 9.4 0.34 11.0 3.2 2.0 2 1 0 2 2 1 0 Basic region leucine zipper PNMA PF14893.6 OWF44393.1 - 3.5e-08 33.2 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 PNMA Retrotran_gag_2 PF14223.6 OWF44393.1 - 0.0019 17.8 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 OWF44393.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Band_7 PF01145.25 OWF44393.1 - 0.2 11.6 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 SPFH domain / Band 7 family Flavodoxin_2 PF02525.17 OWF44395.1 - 1.7e-45 155.1 0.0 2.4e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OWF44395.1 - 3.9e-13 49.4 0.0 1.4e-12 47.6 0.0 1.9 2 1 0 2 2 2 1 NADPH-dependent FMN reductase cNMP_binding PF00027.29 OWF44396.1 - 1.3e-18 66.9 0.1 1.7e-11 44.1 0.1 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Sugarporin_N PF11471.8 OWF44397.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension NDK PF00334.19 OWF44398.1 - 1.1e-17 64.3 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PARP PF00644.20 OWF44399.1 - 2.3e-69 232.9 0.0 5e-69 231.8 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OWF44399.1 - 5.8e-49 165.7 0.9 1.2e-48 164.6 0.4 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 OWF44399.1 - 8.5e-36 122.7 2.2 3.7e-18 66.2 0.4 3.3 4 0 0 4 4 4 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 OWF44399.1 - 4.1e-24 84.1 2.2 9e-24 83.0 2.2 1.6 1 0 0 1 1 1 1 PADR1 (NUC008) domain WGR PF05406.15 OWF44399.1 - 1.7e-21 76.0 0.8 7.8e-21 73.9 0.6 2.4 1 1 1 2 2 2 1 WGR domain BRCT PF00533.26 OWF44399.1 - 4.1e-06 27.1 0.1 1.1e-05 25.7 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OWF44399.1 - 0.00011 22.5 0.0 0.00035 20.9 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain GCN5L1 PF06320.13 OWF44399.1 - 0.056 13.6 0.1 0.056 13.6 0.1 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Spec3 PF15795.5 OWF44401.1 - 1.3e-26 93.0 12.8 1.7e-26 92.6 12.8 1.2 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein DUF3810 PF12725.7 OWF44401.1 - 0.14 11.4 0.3 0.19 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) UPF0669 PF17065.5 OWF44402.1 - 2.2e-38 131.9 0.5 3e-38 131.4 0.5 1.2 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 TBP PF00352.21 OWF44403.1 - 1.2e-68 227.1 0.1 1.7e-34 117.7 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OWF44403.1 - 2.5e-05 24.3 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) AKAP28 PF14469.6 OWF44404.1 - 2.3e-54 182.3 2.4 3.6e-54 181.7 2.4 1.3 1 0 0 1 1 1 1 28 kDa A-kinase anchor PilN_bio_d PF18222.1 OWF44404.1 - 0.069 13.5 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain ANAPC3 PF12895.7 OWF44405.1 - 1.5e-27 95.6 12.8 7.2e-23 80.6 1.2 5.1 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OWF44405.1 - 1.6e-24 84.0 11.2 0.0014 18.5 0.1 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF44405.1 - 6.4e-23 79.6 10.5 9e-07 28.5 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF44405.1 - 2.7e-21 73.9 1.3 0.0081 16.3 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF44405.1 - 2.6e-15 56.5 4.7 3.4e-08 33.7 0.0 6.3 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF44405.1 - 1.2e-12 46.9 2.8 5.1e-05 23.0 0.0 5.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF44405.1 - 7.9e-11 41.8 0.5 1.1 10.2 0.0 6.9 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF44405.1 - 4.7e-10 39.0 0.2 8.1e-05 22.2 0.0 5.3 5 0 0 5 5 5 1 TPR repeat TPR_10 PF13374.6 OWF44405.1 - 1e-09 37.9 4.6 0.0027 17.5 0.4 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF44405.1 - 2.7e-08 34.2 0.9 0.00067 20.1 0.0 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF44405.1 - 7.9e-06 25.9 3.4 45 4.7 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF44405.1 - 2.2e-05 24.5 0.0 0.17 12.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OWF44405.1 - 8.3e-05 22.6 5.4 0.00046 20.2 0.1 3.5 3 1 1 4 4 4 1 Putative TPR-like repeat TPR_16 PF13432.6 OWF44405.1 - 0.00014 22.5 1.2 1.1 9.9 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF44405.1 - 0.00042 20.3 4.9 5.4 7.2 0.0 5.0 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 OWF44405.1 - 0.0057 16.6 0.9 1.3 9.0 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF44405.1 - 0.018 15.6 10.7 58 4.6 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat SNF2_N PF00176.23 OWF44406.1 - 2e-79 266.8 0.2 2e-79 266.8 0.2 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.11 OWF44406.1 - 2.8e-18 65.6 0.0 6.9e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OWF44406.1 - 2.5e-11 43.9 0.0 8.3e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 OWF44406.1 - 7.2e-11 41.7 10.5 1.6e-10 40.6 10.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF44406.1 - 2.7e-10 39.9 6.8 5.2e-10 39.0 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF44406.1 - 3.5e-08 33.2 10.3 7.2e-08 32.2 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF44406.1 - 3.8e-07 30.3 9.1 9e-07 29.1 9.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF44406.1 - 4.2e-06 26.8 9.2 8.6e-06 25.8 9.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF44406.1 - 6.1e-06 26.2 6.8 1.5e-05 24.9 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF44406.1 - 1.2e-05 25.2 7.8 2.5e-05 24.1 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF44406.1 - 5.5e-05 22.9 6.9 0.00011 22.0 6.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ResIII PF04851.15 OWF44406.1 - 0.00021 21.4 0.0 0.034 14.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_10 PF16685.5 OWF44406.1 - 0.0035 17.4 5.9 0.01 15.9 5.9 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 OWF44406.1 - 0.0045 16.8 4.4 0.01 15.7 4.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OWF44406.1 - 0.0075 16.5 4.6 0.0075 16.5 4.6 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OWF44406.1 - 1.5 8.6 8.2 3.5 7.5 8.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 OWF44406.1 - 2.8 7.8 6.1 5.9 6.8 6.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MyTH4 PF00784.17 OWF44407.1 - 9.2e-26 90.5 0.1 9e-25 87.3 0.0 2.7 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 OWF44407.1 - 6.6e-07 29.7 0.0 9.5e-06 26.0 0.0 2.9 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 OWF44407.1 - 0.0009 19.1 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 OWF44407.1 - 0.061 13.7 2.1 0.066 13.6 0.0 2.1 2 0 0 2 2 2 0 FERM C-terminal PH-like domain MyTH4 PF00784.17 OWF44408.1 - 7.7e-21 74.6 0.3 1.8e-20 73.4 0.3 1.6 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 OWF44408.1 - 1.3e-11 44.9 0.0 3.4e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 FERM central domain PTB PF08416.13 OWF44408.1 - 0.0024 18.0 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain ADP_ribosyl_GH PF03747.14 OWF44409.1 - 3.8e-39 135.2 0.2 5.2e-39 134.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase HtrL_YibB PF09612.10 OWF44410.1 - 1.3e-15 57.6 1.4 1.9e-15 57.1 1.4 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Astacin PF01400.24 OWF44411.1 - 3.6e-58 196.3 0.0 7.8e-58 195.2 0.0 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 OWF44411.1 - 1.6e-39 134.1 134.5 5.3e-07 30.1 5.0 9.1 9 0 0 9 9 9 8 ShK domain-like Peptidase_M10 PF00413.24 OWF44411.1 - 0.0025 17.7 3.1 0.37 10.6 1.7 2.5 1 1 1 2 2 2 2 Matrixin Peptidase_M66 PF10462.9 OWF44411.1 - 0.046 12.7 0.1 0.078 11.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 zf-CCCH PF00642.24 OWF44412.1 - 0.017 15.0 0.6 0.017 15.0 0.6 3.8 2 2 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.24 OWF44413.1 - 0.42 10.6 23.6 0.12 12.3 1.0 4.3 3 1 1 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF44413.1 - 0.77 9.9 19.2 3.3 7.9 0.4 4.0 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_4 PF18044.1 OWF44413.1 - 2.8 7.8 21.0 0.92 9.4 2.5 3.5 2 1 1 3 3 3 0 CCCH-type zinc finger SBP56 PF05694.11 OWF44414.1 - 6e-21 74.8 0.0 6.6e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) SBP56 PF05694.11 OWF44415.1 - 2.4e-211 702.4 0.0 2.9e-211 702.1 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 OWF44415.1 - 0.00054 19.3 0.0 0.0017 17.7 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.11 OWF44416.1 - 1.3e-209 696.7 0.0 1.5e-209 696.5 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 OWF44416.1 - 0.0019 17.5 0.0 0.0074 15.6 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Kringle PF00051.18 OWF44417.1 - 1.4e-10 41.3 2.8 1.4e-10 41.3 2.8 2.4 2 1 0 2 2 2 1 Kringle domain 3Beta_HSD PF01073.19 OWF44418.1 - 5.4e-13 48.6 0.0 1.1e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OWF44418.1 - 6.9e-11 42.1 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OWF44418.1 - 9.2e-07 28.3 0.0 9.2e-07 28.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein CDC45 PF02724.14 OWF44418.1 - 0.22 9.8 20.6 1.6 6.9 20.0 2.0 2 0 0 2 2 2 0 CDC45-like protein RR_TM4-6 PF06459.12 OWF44418.1 - 6.8 6.4 26.7 11 5.7 26.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OWF44418.1 - 9.8 4.8 18.5 14 4.3 18.5 1.2 1 0 0 1 1 1 0 Presenilin Apolipoprotein PF01442.18 OWF44419.1 - 0.00079 19.3 12.0 0.0015 18.4 11.7 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF725 PF05267.12 OWF44419.1 - 0.095 12.7 41.5 5.4 7.0 7.4 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF725) EST1 PF10374.9 OWF44419.1 - 1 10.0 32.0 1.8e+04 -8.0 32.0 2.8 1 1 0 1 1 1 0 Telomerase activating protein Est1 Phasin PF05597.11 OWF44419.1 - 1.1 9.3 17.2 8.8 6.4 1.8 3.9 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Gal-3-0_sulfotr PF06990.11 OWF44420.1 - 3.3e-52 177.7 0.9 4.5e-52 177.3 0.9 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF44420.1 - 0.0032 17.4 0.1 0.0071 16.3 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family AMP-binding PF00501.28 OWF44421.1 - 2.7e-97 326.1 0.0 4.1e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF44421.1 - 0.0019 19.1 0.1 0.0047 17.9 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myticin-prepro PF10690.9 OWF44422.1 - 0.017 15.3 2.8 2.7 8.3 0.2 2.3 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel DUF2769 PF10967.8 OWF44423.1 - 0.23 12.2 3.8 0.62 10.8 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2769) TIR_2 PF13676.6 OWF44424.1 - 2.1e-12 47.7 0.0 3.3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF44424.1 - 8.3e-10 38.7 0.1 1.3e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 TIR domain Furin-like PF00757.20 OWF44425.1 - 4.7e-27 94.7 170.1 0.0018 18.2 27.3 13.0 1 1 9 10 10 10 10 Furin-like cysteine rich region Furin-like_2 PF15913.5 OWF44425.1 - 0.017 15.2 0.5 0.017 15.2 0.5 13.4 2 1 9 13 13 13 0 Furin-like repeat, cysteine-rich CAP_GLY PF01302.25 OWF44426.1 - 2e-20 72.6 2.3 2.9e-20 72.0 2.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain ProQ_C PF17516.2 OWF44426.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 ProQ C-terminal domain MADF_DNA_bdg PF10545.9 OWF44427.1 - 3.3e-06 27.3 0.2 6.1e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Ank_5 PF13857.6 OWF44428.1 - 3.1e-16 59.2 0.1 7.4e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF44428.1 - 4.7e-15 55.9 0.0 9.5e-09 35.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF44428.1 - 1.4e-12 46.6 0.4 0.0059 17.0 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OWF44428.1 - 1.2e-11 44.9 0.2 1.4e-05 25.5 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF44428.1 - 1.6e-10 40.9 1.2 0.0034 17.8 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Rhomboid PF01694.22 OWF44429.1 - 1.1e-20 74.2 10.1 1.9e-20 73.4 10.1 1.4 1 0 0 1 1 1 1 Rhomboid family HECT PF00632.25 OWF44430.1 - 1.1e-85 287.8 0.8 2.3e-85 286.8 0.2 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 OWF44430.1 - 4.2e-19 68.9 0.1 1.1e-18 67.6 0.1 1.8 1 0 0 1 1 1 1 WWE domain Arm PF00514.23 OWF44430.1 - 0.00019 21.3 0.6 0.66 10.1 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 OWF44430.1 - 1.5 8.8 4.5 1.3 8.9 0.2 3.0 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central RhoGEF PF00621.20 OWF44431.1 - 5.8e-43 147.3 0.5 1.1e-42 146.3 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 OWF44431.1 - 8.4e-25 86.5 0.5 2.9e-17 62.4 0.0 3.7 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 OWF44431.1 - 1.5e-13 50.9 0.0 5.9e-09 36.2 0.0 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OWF44431.1 - 0.00041 20.7 0.0 1 9.8 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OWF44431.1 - 0.054 13.8 0.0 1.5 9.2 0.0 2.7 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Ribosomal_S7 PF00177.21 OWF44431.1 - 0.11 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e BPL_LplA_LipB PF03099.19 OWF44432.1 - 6e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Rib_hydrolayse PF02267.17 OWF44433.1 - 2.1e-78 263.0 0.0 2.5e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase 7tm_1 PF00001.21 OWF44434.1 - 2.9e-10 39.9 14.6 2.9e-10 39.9 14.6 2.3 3 0 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44434.1 - 5.3e-09 36.1 18.6 5.3e-09 36.1 18.6 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5360 PF17314.2 OWF44434.1 - 0.0082 16.2 1.8 0.015 15.4 1.0 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5360) RB_A PF01858.17 OWF44434.1 - 0.063 13.1 0.9 0.14 12.0 0.9 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain 7tm_1 PF00001.21 OWF44435.1 - 1.2e-16 60.9 18.1 1.7e-16 60.4 18.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44435.1 - 5.5e-09 36.0 16.4 5.5e-09 36.0 16.4 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2207 PF09972.9 OWF44435.1 - 0.32 9.7 2.6 2.5 6.8 0.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Lig_chan-Glu_bd PF10613.9 OWF44436.1 - 3.5e-28 98.1 0.0 6.6e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF44436.1 - 4.3e-16 59.0 0.0 3e-15 56.3 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 adh_short PF00106.25 OWF44437.1 - 3e-52 176.9 0.5 3.6e-52 176.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF44437.1 - 1.9e-49 168.3 0.1 2.9e-49 167.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF44437.1 - 1e-12 48.3 0.2 1.5e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF44437.1 - 0.0018 17.8 0.1 0.0034 16.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF44437.1 - 0.011 15.2 0.2 0.022 14.2 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 OWF44437.1 - 0.019 14.3 0.0 0.068 12.5 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 OWF44437.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Serpin PF00079.20 OWF44438.1 - 2.2e-116 389.2 1.2 2.5e-116 389.0 1.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PID_2 PF14719.6 OWF44442.1 - 1.5e-66 223.7 1.3 2.2e-66 223.2 1.3 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 OWF44442.1 - 0.0004 20.4 0.4 0.0032 17.5 0.4 2.1 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) RRN3 PF05327.11 OWF44442.1 - 2.5 6.6 5.7 3.7 6.0 5.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3546 PF12066.8 OWF44443.1 - 0.065 13.4 1.6 0.16 12.2 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) Methyltransf_31 PF13847.6 OWF44444.1 - 5.5e-23 81.4 0.0 7.6e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF44444.1 - 2.3e-17 63.4 0.0 4.4e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44444.1 - 4.7e-17 62.5 0.0 8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44444.1 - 2.6e-15 56.9 0.0 4e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF44444.1 - 1e-11 44.9 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44444.1 - 5.2e-11 42.3 0.0 7.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OWF44444.1 - 8.8e-08 31.9 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OWF44444.1 - 4e-06 26.9 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OWF44444.1 - 6.9e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 OWF44444.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.11 OWF44444.1 - 3.2e-05 23.6 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 OWF44444.1 - 4.4e-05 23.2 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 OWF44444.1 - 0.00079 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 OWF44444.1 - 0.0096 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GCD14 PF08704.10 OWF44444.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_16 PF10294.9 OWF44444.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 OWF44444.1 - 0.061 14.4 0.0 0.12 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 OWF44444.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Phospholip_A2_1 PF00068.19 OWF44445.1 - 9.1e-32 109.9 5.8 1.1e-31 109.6 5.8 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 OWF44445.1 - 0.039 14.2 15.0 2.2 8.6 15.0 2.4 1 1 0 1 1 1 0 Phospholipase A2 Parvo_coat_N PF08398.10 OWF44445.1 - 0.07 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP1 PLA2G12 PF06951.11 OWF44445.1 - 1.6 8.6 11.4 0.53 10.2 3.7 2.2 1 1 1 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Vault_4 PF17796.1 OWF44446.1 - 1e-05 25.5 2.5 1e+02 3.1 0.0 10.2 5 2 3 8 8 8 0 Major Vault Protein repeat domain NifU_N PF01592.16 OWF44446.1 - 1.2 9.3 40.7 37 4.5 0.4 13.4 3 3 8 15 15 15 0 NifU-like N terminal domain Kinesin PF00225.23 OWF44447.1 - 2e-99 332.7 0.1 2e-99 332.7 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF44447.1 - 1.4e-18 67.3 0.2 8.8e-18 64.7 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 OWF44447.1 - 3.2e-07 30.6 0.0 8.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 OWF44447.1 - 7.9e-07 29.4 1.9 3.3e-06 27.4 0.1 2.9 2 0 0 2 2 2 1 Kinesin protein 1B Kinesin_assoc PF16183.5 OWF44447.1 - 3.1e-06 27.5 11.3 0.00067 19.8 1.8 3.9 3 1 1 4 4 4 2 Kinesin-associated XH PF03469.14 OWF44447.1 - 0.0014 18.5 4.7 0.0054 16.6 4.7 2.0 1 0 0 1 1 1 1 XH domain Yop-YscD_cpl PF16697.5 OWF44447.1 - 0.0017 18.6 0.0 0.0046 17.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Cluap1 PF10234.9 OWF44447.1 - 0.0019 17.7 2.1 0.0055 16.1 2.1 1.8 1 0 0 1 1 1 1 Clusterin-associated protein-1 C2-C2_1 PF11618.8 OWF44447.1 - 0.024 14.7 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 DUF2870 PF11069.8 OWF44447.1 - 0.74 10.2 8.2 6.1 7.3 3.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) ASFV_J13L PF05568.11 OWF44447.1 - 1.3 8.8 9.3 0.26 11.0 4.7 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein Acetyltransf_1 PF00583.25 OWF44448.1 - 2.5e-15 56.7 0.0 3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF44448.1 - 1.2e-07 32.0 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF44448.1 - 2e-05 24.5 0.0 2.5e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF44448.1 - 2.3e-05 24.3 0.0 9.4e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 OWF44448.1 - 0.00033 21.3 0.0 0.00045 20.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OWF44448.1 - 0.018 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 OWF44449.1 - 4.6e-14 52.7 0.1 6.2e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF44449.1 - 5.6e-08 33.1 0.1 1.6e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF44449.1 - 6.7e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF44449.1 - 0.0046 16.9 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 OWF44449.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase APC_N_CC PF16689.5 OWF44449.1 - 0.14 12.2 0.7 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Acetyltransf_1 PF00583.25 OWF44450.1 - 2.4e-15 56.8 0.1 3e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF44450.1 - 3.4e-08 33.8 0.2 6.2e-08 33.0 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF44450.1 - 1.5e-07 31.4 0.1 1.9e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OWF44450.1 - 7.7e-06 26.6 0.0 1.1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF44450.1 - 0.00069 19.5 0.0 0.0027 17.6 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 OWF44450.1 - 0.007 16.5 0.2 0.02 15.0 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase DUF1664 PF07889.12 OWF44451.1 - 0.00039 20.5 2.2 2.2 8.3 0.1 3.4 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) RPW8 PF05659.11 OWF44451.1 - 0.0012 18.5 1.2 2.7 7.7 0.1 3.8 1 1 3 4 4 4 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 UPF0184 PF03670.13 OWF44451.1 - 0.15 12.4 47.0 5.8 7.4 2.2 8.3 1 1 6 7 7 7 0 Uncharacterised protein family (UPF0184) TRIQK PF15168.6 OWF44451.1 - 1.1 9.3 2.6 60 3.6 0.1 3.1 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Hormone_5 PF00184.17 OWF44451.1 - 8 7.4 31.6 23 5.9 5.7 4.8 1 1 2 3 3 3 0 Neurohypophysial hormones, C-terminal Domain DUF1664 PF07889.12 OWF44452.1 - 5.1e-06 26.5 17.3 0.24 11.5 0.1 6.3 2 2 5 7 7 7 4 Protein of unknown function (DUF1664) RPW8 PF05659.11 OWF44452.1 - 9.1e-05 22.2 13.3 11 5.7 0.0 7.5 1 1 9 10 10 10 3 Arabidopsis broad-spectrum mildew resistance protein RPW8 MCPsignal PF00015.21 OWF44452.1 - 0.0001 22.2 1.9 3 7.6 0.0 4.7 2 2 1 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 OWF44452.1 - 0.13 12.8 11.1 10 6.7 0.3 5.9 2 2 4 6 6 6 0 Nucleopolyhedrovirus P10 protein SF-assemblin PF06705.11 OWF44452.1 - 4.4 6.6 13.4 16 4.7 3.4 4.4 1 1 1 4 4 4 0 SF-assemblin/beta giardin DUF1664 PF07889.12 OWF44453.1 - 9.3e-07 28.9 12.7 0.038 14.0 0.9 3.8 1 1 3 4 4 4 4 Protein of unknown function (DUF1664) RPW8 PF05659.11 OWF44453.1 - 1.8e-05 24.5 13.9 1.1 8.9 0.5 5.7 1 1 7 8 8 8 5 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF948 PF06103.11 OWF44453.1 - 5.5e-05 23.4 0.0 2.2 8.6 0.0 4.0 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF948) UPF0184 PF03670.13 OWF44453.1 - 0.00015 22.0 59.0 0.75 10.2 3.2 8.4 1 1 7 8 8 8 5 Uncharacterised protein family (UPF0184) Baculo_PEP_C PF04513.12 OWF44453.1 - 0.00018 21.6 0.0 0.36 10.9 0.0 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 OWF44453.1 - 0.0012 18.7 2.7 0.25 11.2 0.2 3.2 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 OWF44453.1 - 0.023 15.1 11.3 13 6.4 1.8 4.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein NleF_casp_inhib PF16809.5 OWF44453.1 - 0.069 13.1 24.6 3.5 7.5 2.1 4.8 1 1 3 4 4 4 0 NleF caspase inhibitor Laminin_II PF06009.12 OWF44453.1 - 0.17 11.9 0.0 41 4.2 0.0 2.9 1 1 2 3 3 3 0 Laminin Domain II Spc29 PF17082.5 OWF44453.1 - 0.29 10.9 0.5 23 4.7 0.0 3.0 1 1 1 3 3 3 0 Spindle Pole Component 29 DUF848 PF05852.11 OWF44453.1 - 0.38 10.9 2.4 20 5.3 0.0 3.5 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Antifungal_prot PF11402.8 OWF44453.1 - 0.75 10.1 58.9 0.21 11.8 3.1 10.0 2 2 8 10 10 10 0 Antifungal protein UPF0242 PF06785.11 OWF44453.1 - 1 9.4 2.6 30 4.6 0.1 3.3 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus FPP PF05911.11 OWF44453.1 - 9.6 4.2 15.5 26 2.8 9.8 2.4 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil UPF0184 PF03670.13 OWF44454.1 - 9.6e-05 22.7 53.3 2.4 8.6 3.2 9.1 2 2 6 8 8 8 4 Uncharacterised protein family (UPF0184) MCPsignal PF00015.21 OWF44454.1 - 0.00012 22.0 0.0 5.2 6.9 0.0 3.5 1 1 3 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 OWF44454.1 - 0.00016 21.7 7.3 1.8 8.6 0.3 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF1664) RPW8 PF05659.11 OWF44454.1 - 0.0025 17.5 6.3 2.8 7.6 0.1 4.7 1 1 5 6 6 6 3 Arabidopsis broad-spectrum mildew resistance protein RPW8 FPP PF05911.11 OWF44454.1 - 0.31 9.2 6.8 0.18 10.0 4.1 1.7 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Hormone_5 PF00184.17 OWF44454.1 - 0.34 11.8 43.5 7 7.6 10.1 5.7 1 1 2 3 3 3 0 Neurohypophysial hormones, C-terminal Domain Tricorn_C1 PF14684.6 OWF44454.1 - 0.65 10.1 3.0 17 5.6 0.0 3.7 4 0 0 4 4 4 0 Tricorn protease C1 domain NleF_casp_inhib PF16809.5 OWF44454.1 - 0.85 9.5 21.5 7.3 6.5 0.3 4.9 1 1 2 4 4 4 0 NleF caspase inhibitor UPF0242 PF06785.11 OWF44454.1 - 1.4 9.0 3.4 13 5.9 0.1 3.0 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Arm-DNA-bind_5 PF17293.2 OWF44454.1 - 4.4 7.8 7.2 20 5.7 0.5 4.2 2 2 3 5 5 5 0 Arm DNA-binding domain PHF5 PF03660.14 OWF44455.1 - 0.0003 20.9 12.7 0.84 9.9 1.9 4.4 1 1 2 4 4 4 3 PHF5-like protein YkuD_2 PF13645.6 OWF44455.1 - 0.00095 18.7 5.3 8 5.9 0.1 4.3 1 1 3 4 4 4 2 L,D-transpeptidase catalytic domain DUF4892 PF16234.5 OWF44455.1 - 0.0017 17.9 0.1 2.8 7.4 0.0 3.2 1 1 1 3 3 3 1 Domain of unknown function (DUF4892) DUF815 PF05673.13 OWF44455.1 - 0.02 14.0 1.8 7.3 5.7 0.1 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF815) Ureidogly_lyase PF04115.12 OWF44455.1 - 0.03 14.1 5.4 1.4 8.7 0.6 2.6 1 1 0 2 2 2 0 Ureidoglycolate lyase DUF5001 PF16392.5 OWF44455.1 - 0.099 12.6 31.9 0.85 9.6 2.3 4.7 1 1 3 4 4 4 0 Ig-like domain BRAP2 PF07576.12 OWF44455.1 - 0.58 10.4 7.4 18 5.7 0.3 3.6 1 1 1 3 3 3 0 BRCA1-associated protein 2 zf-primase PF09329.11 OWF44455.1 - 1.3 8.8 25.8 18 5.2 0.8 6.2 4 1 3 7 7 7 0 Primase zinc finger Lectin_C PF00059.21 OWF44455.1 - 1.4 9.7 14.0 3.4 8.4 3.0 2.4 1 1 1 2 2 2 0 Lectin C-type domain DCAF17 PF15802.5 OWF44455.1 - 2.1 6.9 17.7 1.1 7.9 1.8 3.0 1 1 2 3 3 3 0 DDB1- and CUL4-associated factor 17 MCPsignal PF00015.21 OWF44455.1 - 3.7 7.3 5.9 15 5.3 0.9 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ATP-synt_E_2 PF08112.11 OWF44455.1 - 6.2 7.2 25.8 17 5.7 0.5 7.3 1 1 8 9 9 9 0 ATP synthase epsilon subunit BLOC1_2 PF10046.9 OWF44455.1 - 6.6 7.1 21.0 5.4 7.4 5.6 3.7 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PHF5 PF03660.14 OWF44456.1 - 0.00019 21.6 12.3 0.76 10.0 2.3 4.3 1 1 2 4 4 4 2 PHF5-like protein YkuD_2 PF13645.6 OWF44456.1 - 0.00079 18.9 5.4 8.2 5.8 0.1 4.4 1 1 4 5 5 5 2 L,D-transpeptidase catalytic domain DUF4892 PF16234.5 OWF44456.1 - 0.0016 17.9 0.1 3 7.3 0.0 3.2 1 1 1 3 3 3 1 Domain of unknown function (DUF4892) DUF815 PF05673.13 OWF44456.1 - 0.022 14.0 1.7 10 5.2 0.1 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF815) Ureidogly_lyase PF04115.12 OWF44456.1 - 0.071 12.9 5.6 3 7.6 0.3 2.6 1 1 1 2 2 2 0 Ureidoglycolate lyase BRAP2 PF07576.12 OWF44456.1 - 0.17 12.1 8.1 20 5.5 0.2 3.8 1 1 2 4 4 4 0 BRCA1-associated protein 2 DUF5001 PF16392.5 OWF44456.1 - 0.22 11.4 31.8 0.72 9.8 2.3 4.5 1 1 5 6 6 6 0 Ig-like domain DCAF17 PF15802.5 OWF44456.1 - 0.47 9.1 16.8 1.1 7.8 1.9 3.0 1 1 2 3 3 3 0 DDB1- and CUL4-associated factor 17 zf-primase PF09329.11 OWF44456.1 - 1.2 9.0 25.7 17 5.3 0.7 6.2 4 1 3 7 7 7 0 Primase zinc finger MCPsignal PF00015.21 OWF44456.1 - 2.6 7.8 5.1 15 5.4 0.4 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 OWF44456.1 - 7.6 6.9 20.2 7.3 7.0 5.3 3.7 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP-synt_E_2 PF08112.11 OWF44456.1 - 8.3 6.8 25.1 18 5.7 0.4 7.2 1 1 6 8 8 8 0 ATP synthase epsilon subunit MSG PF02349.15 OWF44457.1 - 0.012 15.7 35.7 11 6.3 0.9 7.8 3 2 4 7 7 7 0 Major surface glycoprotein DUF4892 PF16234.5 OWF44457.1 - 0.17 11.4 0.0 11 5.4 0.0 3.0 2 2 0 3 3 3 0 Domain of unknown function (DUF4892) PrkA PF06798.12 OWF44457.1 - 0.2 11.2 3.3 6.2 6.4 0.0 3.3 1 1 1 3 3 3 0 PrkA serine protein kinase C-terminal domain DUF3731 PF12531.8 OWF44457.1 - 0.25 11.1 0.7 17 5.1 0.0 2.9 1 1 3 4 4 4 0 DNA-K related protein Arrestin_N PF00339.29 OWF44458.1 - 8.5e-35 120.0 0.1 1e-32 113.2 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF44458.1 - 1e-27 97.2 0.0 8.8e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 OWF44458.1 - 0.039 13.7 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Rgp1 PF08737.10 OWF44458.1 - 0.17 11.0 0.0 2 7.5 0.0 2.3 2 1 1 3 3 3 0 Rgp1 zf-C2H2_4 PF13894.6 OWF44460.1 - 7.4e-23 79.3 48.5 0.00023 21.7 0.8 9.6 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF44460.1 - 2.8e-16 59.0 51.5 1.3e-05 25.4 1.7 9.2 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-met PF12874.7 OWF44460.1 - 1e-07 32.1 27.2 0.027 14.8 0.3 7.0 7 0 0 7 7 6 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF44460.1 - 1.5e-06 28.4 34.8 0.00011 22.4 0.7 5.7 4 2 2 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OWF44460.1 - 2.7e-06 27.2 1.8 0.00039 20.4 0.1 8.4 9 0 0 9 9 9 2 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 OWF44460.1 - 9.9e-06 25.9 14.2 0.025 15.0 0.1 5.6 5 0 0 5 5 5 2 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 OWF44460.1 - 0.0001 22.5 25.2 0.027 14.8 0.3 6.5 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF44460.1 - 0.00037 20.8 34.2 0.29 11.5 2.3 5.4 4 2 2 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 OWF44460.1 - 0.0047 17.3 15.7 0.12 12.8 0.0 5.4 5 0 0 5 5 5 1 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 OWF44460.1 - 0.0051 16.6 5.8 0.2 11.5 0.0 4.9 6 0 0 6 6 6 1 GAGA factor zf-H2C2_2 PF13465.6 OWF44460.1 - 0.021 15.2 0.1 0.021 15.2 0.1 9.3 11 0 0 11 11 11 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 OWF44460.1 - 0.061 13.1 0.1 0.061 13.1 0.1 6.5 7 0 0 7 7 6 0 zinc-finger C2H2-type MutH PF02976.15 OWF44460.1 - 0.061 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH zf-MYST PF17772.1 OWF44460.1 - 0.076 12.6 5.4 1 9.0 0.8 3.4 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2_3rep PF18868.1 OWF44460.1 - 0.15 12.7 0.3 0.15 12.7 0.3 5.6 4 2 3 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 OWF44460.1 - 0.16 12.1 5.1 1 9.5 0.1 3.5 3 0 0 3 3 3 0 Zic proteins zinc finger domain Rad50_zn_hook PF04423.14 OWF44460.1 - 0.23 11.3 3.7 17 5.3 0.0 3.8 3 0 0 3 3 3 0 Rad50 zinc hook motif PhnA_Zn_Ribbon PF08274.12 OWF44460.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.2 4 0 0 4 4 3 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.6 OWF44460.1 - 1.5 8.3 15.7 27 4.3 0.0 6.1 6 0 0 6 6 6 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 OWF44460.1 - 2.9 8.0 7.2 5.8 7.1 0.1 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-Sec23_Sec24 PF04810.15 OWF44460.1 - 3.5 7.7 13.2 0.4 10.8 0.1 4.6 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger EF-hand_7 PF13499.6 OWF44461.1 - 2.1e-12 47.3 12.4 9.4e-11 42.0 3.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF44461.1 - 2.9e-12 45.4 3.6 2e-05 24.1 0.1 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OWF44461.1 - 3e-11 42.0 11.6 0.00017 20.9 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF44461.1 - 2.5e-07 30.4 8.4 0.00014 21.6 1.9 3.3 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF44461.1 - 0.043 14.1 1.7 0.52 10.6 1.2 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PB1 PF00564.24 OWF44461.1 - 0.062 13.2 1.0 2.5 8.1 0.0 2.9 1 1 2 3 3 3 0 PB1 domain SBDS PF01172.18 OWF44461.1 - 0.066 13.3 0.0 2.3 8.3 0.1 2.3 2 1 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein EF-hand_5 PF13202.6 OWF44461.1 - 0.22 11.1 9.9 1.1 8.8 0.2 3.2 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 OWF44461.1 - 0.25 11.3 5.1 0.68 9.9 0.5 2.8 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Cas_Csy4 PF09618.10 OWF44462.1 - 0.4 10.8 4.6 0.12 12.5 0.9 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Latarcin PF10279.9 OWF44462.1 - 0.51 10.8 0.1 0.51 10.8 0.1 3.0 2 2 0 2 2 2 0 Latarcin precursor Med27 PF11571.8 OWF44465.1 - 3.8e-25 88.1 0.4 8.6e-25 86.9 0.4 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 XPG_I PF00867.18 OWF44466.1 - 6.3e-22 77.7 0.0 1.6e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OWF44466.1 - 1.8e-10 41.2 0.0 4.3e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain APH PF01636.23 OWF44467.1 - 6.2e-14 52.5 0.0 1.2e-13 51.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Transglut_core PF01841.19 OWF44468.1 - 0.01 16.3 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Flavoprotein PF02441.19 OWF44469.1 - 9.9e-51 171.6 0.0 1.1e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Nbas_N PF15492.6 OWF44470.1 - 1.4e-82 277.3 0.1 2.2e-82 276.6 0.1 1.3 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 OWF44470.1 - 0.0082 17.0 5.9 0.13 13.2 0.2 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF44470.1 - 0.071 13.4 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RNase_H2-Ydr279 PF09468.10 OWF44470.1 - 0.085 13.0 1.6 1.1 9.4 0.1 3.1 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain PfkB PF00294.24 OWF44471.1 - 5.4e-62 209.8 1.6 6.4e-62 209.6 1.6 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PAP2_C PF14360.6 OWF44472.1 - 2.8e-23 82.2 6.2 2.8e-23 82.2 6.2 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OWF44472.1 - 0.00084 19.1 3.0 0.00084 19.1 3.0 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OWF44473.1 - 1e-23 83.6 7.1 1e-23 83.6 7.1 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OWF44473.1 - 0.0004 20.2 2.9 0.0004 20.2 2.9 1.8 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OWF44473.1 - 0.019 14.7 3.9 0.041 13.6 3.9 1.5 1 1 0 1 1 1 0 PAP2 superfamily DUF1286 PF06939.11 OWF44473.1 - 0.05 13.9 0.5 0.43 10.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) Cu_amine_oxid PF01179.20 OWF44474.1 - 8.9e-117 390.5 0.7 1.1e-116 390.2 0.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OWF44474.1 - 3.2e-09 36.9 0.0 6.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Zip PF02535.22 OWF44477.1 - 3e-65 220.6 8.3 3.8e-65 220.3 8.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ISK_Channel PF02060.15 OWF44477.1 - 0.25 11.1 2.8 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Slow voltage-gated potassium channel EptA_B_N PF08019.12 OWF44477.1 - 0.27 11.1 3.5 0.18 11.7 0.6 2.2 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB DUF2298 PF10060.9 OWF44477.1 - 8.9 4.9 10.0 7.6 5.1 3.8 2.5 2 1 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) Zip PF02535.22 OWF44478.1 - 1.3e-64 218.6 7.2 1.5e-64 218.3 7.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter EptA_B_N PF08019.12 OWF44478.1 - 0.032 14.1 1.0 0.14 12.1 1.0 2.0 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB DUF5083 PF16890.5 OWF44478.1 - 0.063 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) DUF2298 PF10060.9 OWF44478.1 - 0.27 9.9 6.5 0.26 10.0 1.7 2.2 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) Siah-Interact_N PF09032.11 OWF44479.1 - 0.36 11.2 7.6 13 6.2 0.2 3.9 3 1 0 3 3 2 0 Siah interacting protein, N terminal GAS PF13851.6 OWF44479.1 - 0.37 10.1 17.5 0.083 12.2 4.2 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Csm2_III-A PF03750.13 OWF44479.1 - 0.9 10.4 7.2 0.15 12.9 1.3 2.7 2 1 0 2 2 2 0 Csm2 Type III-A TMF_TATA_bd PF12325.8 OWF44479.1 - 1.3 9.2 20.0 0.092 13.0 6.0 3.7 5 0 0 5 5 5 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 OWF44479.1 - 1.7 9.3 12.6 38 5.0 0.1 4.7 5 0 0 5 5 5 0 SlyX CHD5 PF04420.14 OWF44479.1 - 1.9 8.3 6.8 5.4 6.8 0.3 3.1 3 0 0 3 3 3 0 CHD5-like protein CC2-LZ PF16516.5 OWF44479.1 - 2 8.8 13.5 2.4 8.6 0.2 4.3 4 0 0 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Cep57_CLD_2 PF14197.6 OWF44479.1 - 2.5 8.3 17.0 0.071 13.2 1.3 3.6 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 NYD-SP28_assoc PF14775.6 OWF44479.1 - 2.9 8.1 12.2 8.6 6.6 0.2 4.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain Ax_dynein_light PF10211.9 OWF44479.1 - 2.9 7.8 11.9 0.73 9.7 2.2 3.0 3 0 0 3 3 3 0 Axonemal dynein light chain FapA PF03961.13 OWF44479.1 - 4.9 5.6 8.4 3.1 6.3 1.0 2.8 4 0 0 4 4 4 0 Flagellar Assembly Protein A THOC7 PF05615.13 OWF44479.1 - 5.3 7.3 14.1 2.9 8.2 1.2 3.8 3 0 0 3 3 3 0 Tho complex subunit 7 Uso1_p115_C PF04871.13 OWF44479.1 - 8.8 6.7 22.5 1.1 9.7 5.1 3.9 4 0 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_lid_9 PF17871.1 OWF44479.1 - 8.9 6.3 9.8 23 5.0 1.1 3.7 3 0 0 3 3 3 0 AAA lid domain zf-RING_2 PF13639.6 OWF44480.1 - 2.2e-13 50.3 8.3 2.2e-13 50.3 8.3 2.2 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 OWF44480.1 - 1.7e-09 37.7 2.8 1.7e-09 37.7 2.8 2.7 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_2 PF13923.6 OWF44480.1 - 3.1e-08 33.3 9.2 3.1e-08 33.3 9.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF44480.1 - 1.6e-07 30.9 5.8 1.6e-07 30.9 5.8 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OWF44480.1 - 3.8e-07 30.0 2.8 3.8e-07 30.0 2.8 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF44480.1 - 2.7e-06 27.1 11.9 9.2e-05 22.2 4.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF44480.1 - 3.3e-06 27.3 8.9 3.3e-06 27.3 8.9 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF44480.1 - 3.2e-05 23.7 8.5 3.2e-05 23.7 8.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF44480.1 - 0.00015 21.6 16.0 0.00059 19.7 5.9 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF44480.1 - 0.0059 16.6 4.4 0.0059 16.6 4.4 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OWF44480.1 - 0.032 14.1 5.8 0.032 14.1 5.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 OWF44480.1 - 0.034 14.1 10.7 1.7 8.6 1.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_12 PF11331.8 OWF44480.1 - 0.04 13.7 0.2 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain zinc-ribbons_6 PF07191.12 OWF44480.1 - 0.09 12.8 10.4 0.4 10.7 0.6 2.8 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 OWF44480.1 - 0.12 12.4 7.7 0.32 11.1 0.6 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 OWF44480.1 - 0.13 12.1 4.5 0.3 10.9 4.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OWF44480.1 - 0.29 10.9 14.3 0.13 12.1 4.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OWF44480.1 - 0.49 10.3 17.9 1.6 8.7 6.6 2.9 2 2 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 OWF44480.1 - 0.61 9.8 13.0 0.048 13.3 6.2 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zinc_ribbon_15 PF17032.5 OWF44480.1 - 0.88 10.4 8.9 0.7 10.7 1.4 2.3 2 0 0 2 2 2 0 zinc-ribbon family LIM PF00412.22 OWF44480.1 - 2.9 8.2 12.0 23 5.3 4.0 3.6 2 2 1 3 3 3 0 LIM domain DUF1272 PF06906.11 OWF44480.1 - 8.4 6.6 9.3 15 5.8 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-Di19 PF05605.12 OWF44480.1 - 10 6.5 10.8 51 4.3 0.0 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding BAR PF03114.18 OWF44481.1 - 4.5e-74 249.1 7.9 5.8e-74 248.7 7.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 OWF44481.1 - 3.7e-14 52.3 0.1 6.6e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 OWF44481.1 - 5.8e-14 51.9 8.7 1.2e-12 47.6 2.7 2.4 3 0 0 3 3 3 2 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_1 PF00018.28 OWF44481.1 - 1e-12 47.4 0.1 1.8e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF44481.1 - 1.7e-11 43.6 0.1 3.2e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 OWF44481.1 - 0.0038 17.0 5.9 0.018 14.7 5.9 2.2 1 1 0 1 1 1 1 BAR domain of APPL family Imm6 PF14434.6 OWF44481.1 - 0.037 13.9 0.1 0.087 12.8 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm6 CAF1A PF12253.8 OWF44482.1 - 6.1e-24 84.0 8.3 6.1e-24 84.0 8.3 5.8 4 1 1 5 5 5 1 Chromatin assembly factor 1 subunit A CAF1-p150_C2 PF15539.6 OWF44482.1 - 1.1e-11 44.8 7.6 3.6e-06 26.7 0.4 4.0 2 1 1 3 3 3 2 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term zf-SNAP50_C PF12251.8 OWF44483.1 - 2.1e-75 252.8 0.1 3.1e-75 252.3 0.1 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF1761 PF08570.10 OWF44484.1 - 3.4e-12 46.7 1.3 4e-12 46.5 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CPBP PF02517.16 OWF44484.1 - 0.056 13.8 1.6 0.14 12.6 1.6 1.7 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease MFS_1 PF07690.16 OWF44485.1 - 2e-43 148.7 45.2 8.9e-27 93.9 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF44485.1 - 0.00042 19.3 27.5 0.056 12.3 27.5 4.0 1 1 0 1 1 1 1 MFS_1 like family ACT_3 PF10000.9 OWF44486.1 - 4.9e-12 45.6 38.6 9.2 6.3 0.1 20.1 4 4 19 23 23 23 1 ACT domain Bactofilin PF04519.13 OWF44486.1 - 1.5e-10 41.2 19.6 0.56 10.5 0.1 9.9 1 1 9 10 10 10 3 Polymer-forming cytoskeletal Hyphal_reg_CWP PF11765.8 OWF44486.1 - 3.2e-07 29.6 76.4 0.0029 16.6 9.2 5.9 1 1 5 7 7 7 7 Hyphally regulated cell wall protein N-terminal CaM-KIIN PF15170.6 OWF44486.1 - 2.8e-06 27.4 1.5 74 3.6 0.0 9.5 9 3 3 12 12 12 0 Calcium/calmodulin-dependent protein kinase II inhibitor Imm1 PF14430.6 OWF44486.1 - 0.0002 22.0 20.0 4.5 8.0 0.3 8.7 1 1 3 5 5 5 1 Immunity protein Imm1 PMBR PF09373.10 OWF44486.1 - 0.00041 20.4 68.2 57 4.1 0.3 25.8 17 11 14 31 31 31 0 Pseudomurein-binding repeat SoxY PF13501.6 OWF44486.1 - 0.00067 19.9 23.4 5.2 7.3 0.2 8.6 2 2 9 11 11 11 3 Sulfur oxidation protein SoxY Mer2 PF09074.10 OWF44486.1 - 0.23 11.3 15.0 53 3.5 0.1 8.4 5 4 3 9 9 9 0 Mer2 Glucodextran_B PF09136.10 OWF44486.1 - 0.57 10.6 149.8 1.5 9.2 0.7 31.2 1 1 33 34 34 34 0 Glucodextranase, domain B Leu_zip PF15294.6 OWF44486.1 - 5.3 6.5 11.5 51 3.2 0.0 6.3 5 3 3 8 8 8 0 Leucine zipper Aldedh PF00171.22 OWF44487.1 - 3.7e-181 602.7 0.0 4.1e-181 602.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lebercilin PF15619.6 OWF44488.1 - 0.00097 18.9 32.9 0.00097 18.9 32.9 13.5 4 3 9 14 14 14 6 Ciliary protein causing Leber congenital amaurosis disease EGF_CA PF07645.15 OWF44489.1 - 1.5e-17 63.5 36.6 1.1e-07 31.9 12.3 3.4 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF44489.1 - 9.4e-12 45.0 37.7 4.1e-10 39.8 10.1 3.4 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF44489.1 - 1.9e-09 37.2 18.9 7.2e-09 35.4 0.6 3.3 3 0 0 3 3 3 2 Complement Clr-like EGF-like Collagen PF01391.18 OWF44489.1 - 2.4e-05 24.0 6.8 4.1e-05 23.3 6.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) EGF_3 PF12947.7 OWF44489.1 - 0.00023 21.3 30.4 0.025 14.8 11.4 3.5 3 0 0 3 3 3 2 EGF domain Orf78 PF06024.12 OWF44489.1 - 0.0086 16.4 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) DUF5305 PF17231.2 OWF44489.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) hEGF PF12661.7 OWF44489.1 - 0.66 10.7 34.4 1.3 9.7 10.6 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF C2-set_2 PF08205.12 OWF44490.1 - 0.00027 20.9 0.9 0.0013 18.8 0.2 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 OWF44490.1 - 0.0023 18.5 6.0 0.0047 17.5 0.5 3.2 3 1 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 OWF44490.1 - 0.06 13.5 1.5 1.9 8.7 0.7 3.3 2 1 0 2 2 2 0 Immunoglobulin domain CBM_14 PF01607.24 OWF44490.1 - 4.7 7.4 7.4 2.7 8.2 5.1 1.8 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain TSP_1 PF00090.19 OWF44491.1 - 1.6e-10 41.0 114.6 2.3e-05 24.5 9.4 9.2 8 2 0 8 8 8 5 Thrombospondin type 1 domain PLAC PF08686.11 OWF44491.1 - 1.3e-05 25.9 11.7 0.0001 23.0 11.7 2.8 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Ig_3 PF13927.6 OWF44491.1 - 0.00014 22.4 0.0 0.00055 20.5 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain DUF3746 PF12562.8 OWF44491.1 - 0.18 11.8 3.3 0.73 9.8 3.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) Nucleos_tra2_C PF07662.13 OWF44492.1 - 2.6e-70 236.5 1.3 2.6e-70 236.5 1.3 2.9 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF44492.1 - 3.6e-23 81.9 3.1 3.6e-23 81.9 3.1 3.2 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OWF44492.1 - 1.6e-05 25.2 5.1 1.6e-05 25.2 5.1 4.7 5 1 1 6 6 6 1 Nucleoside recognition SLATT_5 PF18160.1 OWF44492.1 - 3.9 6.8 5.6 11 5.3 5.6 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Ribosomal_L24e PF01246.20 OWF44493.1 - 7.4e-25 87.0 2.9 7.4e-25 87.0 2.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e Collagen PF01391.18 OWF44494.1 - 1.7e-26 91.7 78.6 1.8e+04 -16.2 78.6 4.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.6 OWF44494.1 - 1.4e-23 82.9 76.8 8.4e-09 35.6 10.9 5.5 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF44494.1 - 1.7e-10 40.6 37.4 0.00059 19.7 1.9 5.2 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF44494.1 - 2e-10 40.7 73.1 1.6e-06 28.2 11.0 5.7 6 0 0 6 6 6 5 Calcium-binding EGF domain 7tm_1 PF00001.21 OWF44495.1 - 1.8e-49 168.5 11.5 2.1e-49 168.2 11.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF44495.1 - 1.3e-11 44.3 9.1 2.8e-11 43.3 9.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF44495.1 - 5.8e-05 23.0 13.1 7.2e-05 22.7 10.0 2.3 1 1 1 2 2 2 1 Olfactory receptor SOUL PF04832.12 OWF44496.1 - 4.2e-32 111.6 1.5 4.9e-32 111.4 1.5 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein SOUL PF04832.12 OWF44497.1 - 1.4e-21 77.4 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein KH_1 PF00013.29 OWF44498.1 - 1e-26 92.5 2.2 3.3e-14 52.4 0.3 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 OWF44498.1 - 2e-09 37.1 7.0 3.5e-09 36.4 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44498.1 - 6.9e-07 29.0 7.1 1.7e-06 27.8 7.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF44498.1 - 0.00045 20.5 7.4 0.00096 19.4 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain KH_2 PF07650.17 OWF44498.1 - 0.0019 18.0 0.4 0.41 10.5 0.0 2.5 3 0 0 3 3 2 1 KH domain zf-RING_5 PF14634.6 OWF44498.1 - 0.0021 18.0 6.3 0.0053 16.7 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF44498.1 - 0.0028 17.5 7.5 0.0064 16.3 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_4 PF13083.6 OWF44498.1 - 0.004 17.0 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 KH domain zf-C3HC4_4 PF15227.6 OWF44498.1 - 0.11 12.7 7.8 0.25 11.5 7.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING NETI PF14044.6 OWF44498.1 - 0.2 11.4 0.7 9.8 6.0 0.0 2.3 2 0 0 2 2 2 0 NETI protein zf-P11 PF03854.14 OWF44498.1 - 0.55 9.9 3.0 1.1 9.0 3.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_2 PF13923.6 OWF44498.1 - 1.8 8.5 7.8 4.3 7.3 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF44498.1 - 2 8.5 6.5 1.8 8.6 3.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger SNF2_N PF00176.23 OWF44499.1 - 3.4e-68 229.9 0.0 6.4e-68 229.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF44499.1 - 1.8e-19 70.1 0.0 1.5e-18 67.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Beta-lactamase PF00144.24 OWF44500.1 - 1.2e-49 169.3 0.1 2.4e-49 168.3 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase DUF5421 PF17458.2 OWF44501.1 - 0.031 13.7 0.3 0.04 13.3 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) SAE2 PF08573.10 OWF44502.1 - 0.69 11.0 4.9 9.9 7.3 2.7 2.1 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus AIG1 PF04548.16 OWF44504.1 - 7e-62 208.5 0.0 7e-62 208.5 0.0 1.8 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF44504.1 - 7.6e-06 26.0 0.1 1.5e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OWF44504.1 - 0.0023 18.4 5.0 0.047 14.2 0.2 2.5 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 OWF44504.1 - 0.0033 17.3 0.4 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FYVE PF01363.21 OWF44504.1 - 0.03 14.5 3.0 0.12 12.6 3.0 2.0 1 0 0 1 1 1 0 FYVE zinc finger AAA_16 PF13191.6 OWF44504.1 - 0.035 14.5 1.0 0.098 13.0 0.9 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF2655 PF10848.8 OWF44504.1 - 0.036 14.4 0.4 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) Cbl_N PF02262.16 OWF44504.1 - 0.039 14.0 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 UPF0052 PF01933.18 OWF44504.1 - 0.07 12.4 1.0 0.12 11.5 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 FeoB_N PF02421.18 OWF44504.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 OWF44504.1 - 0.089 12.1 0.7 0.7 9.2 0.0 2.4 2 1 0 3 3 3 0 FtsK/SpoIIIE family DUF1682 PF07946.14 OWF44504.1 - 0.099 11.8 9.3 0.086 12.0 8.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) Dcc1 PF09724.9 OWF44504.1 - 0.16 11.2 4.7 0.33 10.2 4.4 1.4 1 1 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 AAA_29 PF13555.6 OWF44504.1 - 0.18 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 OWF44504.1 - 0.19 10.8 1.8 0.19 10.8 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 OWF44504.1 - 0.31 10.7 2.1 0.67 9.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain PEARLI-4 PF05278.12 OWF44504.1 - 0.31 10.6 12.5 0.042 13.4 7.9 1.7 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Allexi_40kDa PF05549.11 OWF44504.1 - 0.36 10.3 4.0 0.53 9.8 4.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Borrelia_P83 PF05262.11 OWF44504.1 - 1.1 7.7 8.3 1.5 7.2 8.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF87 PF01935.17 OWF44504.1 - 1.1 9.2 5.8 12 5.9 1.5 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain TMPIT PF07851.13 OWF44504.1 - 1.5 8.0 5.8 2 7.6 5.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Guanylate_kin PF00625.21 OWF44504.1 - 1.5 8.4 6.3 2.1 8.0 0.0 2.8 2 1 0 2 2 2 0 Guanylate kinase Dynamin_N PF00350.23 OWF44504.1 - 2.5 8.1 12.5 1.8e+02 2.1 12.5 2.7 1 1 0 1 1 1 0 Dynamin family CENP-H PF05837.12 OWF44504.1 - 8.6 6.8 12.5 5.1 7.5 0.6 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) AIG1 PF04548.16 OWF44505.1 - 8.1e-62 208.3 0.2 8.1e-62 208.3 0.2 2.2 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF44505.1 - 3.3e-07 30.4 0.0 3.3e-07 30.4 0.0 2.2 2 2 0 2 2 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF44505.1 - 0.00023 21.1 0.1 0.00023 21.1 0.1 2.9 3 1 1 4 4 4 1 RsgA GTPase FeoB_N PF02421.18 OWF44505.1 - 0.00044 19.8 0.0 0.00094 18.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Csm1_N PF18504.1 OWF44505.1 - 0.0031 17.8 17.9 0.087 13.2 5.3 2.5 2 0 0 2 2 2 2 Csm1 N-terminal domain ATG16 PF08614.11 OWF44505.1 - 0.0071 16.6 12.7 0.011 16.0 12.7 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FTA4 PF13093.6 OWF44505.1 - 0.018 14.9 7.7 0.029 14.2 7.7 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Golgin_A5 PF09787.9 OWF44505.1 - 0.018 14.5 20.3 0.027 13.9 20.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 ABC_tran PF00005.27 OWF44505.1 - 0.021 15.4 0.4 0.021 15.4 0.4 2.6 2 2 0 2 2 1 0 ABC transporter Ribosomal_L29 PF00831.23 OWF44505.1 - 0.023 14.6 13.2 0.37 10.8 3.2 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein PduV-EutP PF10662.9 OWF44505.1 - 0.025 14.3 0.2 0.79 9.5 0.1 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Caldesmon PF02029.15 OWF44505.1 - 0.03 13.1 15.3 0.046 12.5 15.3 1.3 1 0 0 1 1 1 0 Caldesmon APG6_N PF17675.1 OWF44505.1 - 0.03 14.8 20.3 0.055 14.0 20.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 OWF44505.1 - 0.036 13.6 5.3 0.046 13.3 5.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 OWF44505.1 - 0.045 14.4 7.9 2.5 8.8 1.2 2.6 1 1 1 2 2 2 0 SlyX Borrelia_P83 PF05262.11 OWF44505.1 - 0.067 11.7 19.4 0.094 11.2 19.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 OWF44505.1 - 0.11 11.8 6.1 0.18 11.2 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OWF44505.1 - 0.11 11.5 12.7 0.18 10.9 12.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliD_N PF02465.18 OWF44505.1 - 0.15 12.7 9.2 2.1 9.1 1.1 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HIP1_clath_bdg PF16515.5 OWF44505.1 - 0.19 12.4 20.9 1.3 9.7 7.4 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 OWF44505.1 - 0.2 11.9 19.8 0.051 13.8 16.2 1.8 2 1 1 3 3 1 0 Seryl-tRNA synthetase N-terminal domain Neur_chan_memb PF02932.16 OWF44505.1 - 0.21 11.6 5.0 0.32 11.0 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PEPcase PF00311.17 OWF44505.1 - 0.29 9.1 4.9 0.4 8.7 4.9 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase IF-2B PF01008.17 OWF44505.1 - 0.33 10.1 4.6 0.46 9.6 4.1 1.4 1 1 0 1 1 1 0 Initiation factor 2 subunit family DUF948 PF06103.11 OWF44505.1 - 0.56 10.5 2.8 0.72 10.2 0.4 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 OWF44505.1 - 0.69 9.2 8.1 0.22 10.8 3.8 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4200 PF13863.6 OWF44505.1 - 0.84 10.0 29.0 1.1 9.7 27.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 OWF44505.1 - 1.1 7.1 13.2 1.6 6.6 13.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3391 PF11871.8 OWF44505.1 - 1.4 9.5 11.6 45 4.6 11.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CTNNB1_binding PF08347.11 OWF44505.1 - 1.5 9.0 9.2 2.5 8.3 9.2 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding CCDC-167 PF15188.6 OWF44505.1 - 1.5 9.2 25.5 1.4 9.3 10.2 3.5 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 TPX2 PF06886.11 OWF44505.1 - 1.5 9.1 19.0 2.5 8.4 6.2 3.0 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) EzrA PF06160.12 OWF44505.1 - 1.7 6.7 20.5 7.4 4.6 20.6 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Presenilin PF01080.17 OWF44505.1 - 1.9 7.2 3.3 2.3 6.9 3.3 1.1 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.16 OWF44505.1 - 2.6 6.9 6.0 3.3 6.5 6.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_22 PF13401.6 OWF44505.1 - 2.6 8.3 6.1 0.96 9.7 0.3 2.8 2 2 0 2 2 2 0 AAA domain Prp19 PF08606.11 OWF44505.1 - 2.7 8.1 5.5 22 5.1 0.4 2.5 1 1 1 2 2 2 0 Prp19/Pso4-like Spc7 PF08317.11 OWF44505.1 - 2.8 6.7 21.3 4.6 6.0 21.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1690 PF07956.11 OWF44505.1 - 2.9 8.3 20.1 0.44 11.0 8.9 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) HemX PF04375.14 OWF44505.1 - 3 7.0 9.4 4.7 6.4 9.4 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3418 PF11898.8 OWF44505.1 - 3.2 6.3 11.0 2.5 6.7 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3418) DUF1664 PF07889.12 OWF44505.1 - 3.2 7.8 10.9 0.58 10.2 6.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 OWF44505.1 - 4 7.9 16.2 5.4 7.4 12.6 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Fez1 PF06818.15 OWF44505.1 - 4.1 7.8 22.7 5.7 7.3 22.2 1.4 1 1 0 1 1 1 0 Fez1 DUF2508 PF10704.9 OWF44505.1 - 4.3 7.6 19.9 13 6.0 7.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) Sec62 PF03839.16 OWF44505.1 - 4.3 6.8 7.8 6.7 6.2 7.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Med21 PF11221.8 OWF44505.1 - 5.2 7.3 17.8 3.3 7.9 7.0 2.5 3 0 0 3 3 2 0 Subunit 21 of Mediator complex AAA_11 PF13086.6 OWF44505.1 - 6.5 6.5 11.2 13 5.5 11.2 1.5 1 0 0 1 1 1 0 AAA domain CENP-H PF05837.12 OWF44505.1 - 6.6 7.2 17.5 4.9 7.6 15.3 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF724 PF05266.14 OWF44505.1 - 7.1 6.4 23.8 75 3.1 23.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Med9 PF07544.13 OWF44505.1 - 7.6 6.7 15.8 90 3.3 15.9 2.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TolA_bind_tri PF16331.5 OWF44505.1 - 7.8 6.7 16.2 4.2 7.5 5.1 2.9 2 1 1 3 3 2 0 TolA binding protein trimerisation DUF1542 PF07564.11 OWF44505.1 - 8.3 6.6 11.8 12 6.1 1.5 2.4 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) MerR-DNA-bind PF09278.11 OWF44505.1 - 8.5 7.0 9.3 24 5.6 1.4 2.8 2 0 0 2 2 2 0 MerR, DNA binding AAA_24 PF13479.6 OWF44505.1 - 8.6 6.0 10.6 0.95 9.1 0.3 2.5 2 1 0 2 2 2 0 AAA domain FapA PF03961.13 OWF44505.1 - 9.4 4.7 20.1 22 3.5 1.7 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A HSP70 PF00012.20 OWF44505.1 - 9.4 4.3 11.6 13 3.8 11.6 1.2 1 0 0 1 1 1 0 Hsp70 protein AIG1 PF04548.16 OWF44506.1 - 4.6e-67 225.4 0.7 4.6e-67 225.4 0.7 2.4 2 1 1 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 OWF44506.1 - 1.1e-07 31.9 1.3 2.4e-07 30.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF445 PF04286.12 OWF44506.1 - 0.00048 20.0 10.0 0.0006 19.7 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Mitovir_RNA_pol PF05919.11 OWF44506.1 - 0.0008 18.7 8.5 0.0011 18.3 8.5 1.1 1 0 0 1 1 1 1 Mitovirus RNA-dependent RNA polymerase FeoB_N PF02421.18 OWF44506.1 - 0.003 17.1 0.6 0.0081 15.7 0.0 2.1 3 0 0 3 3 3 1 Ferrous iron transport protein B Exonuc_VII_L PF02601.15 OWF44506.1 - 0.0094 15.6 7.5 0.014 15.0 7.5 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit RsgA_GTPase PF03193.16 OWF44506.1 - 0.02 14.8 0.0 0.02 14.8 0.0 3.5 2 1 2 5 5 5 0 RsgA GTPase PIN_8 PF18476.1 OWF44506.1 - 0.1 12.4 19.3 0.11 12.3 0.5 2.2 1 1 1 2 2 2 0 PIN like domain L1R_F9L PF02442.17 OWF44506.1 - 0.16 11.8 5.3 0.4 10.5 5.3 1.8 1 1 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses ARGLU PF15346.6 OWF44506.1 - 0.33 10.8 27.9 0.39 10.6 27.2 1.5 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 CorA PF01544.18 OWF44506.1 - 0.64 9.3 11.8 0.73 9.1 10.9 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Prominin PF05478.11 OWF44506.1 - 0.66 7.9 17.0 1.8 6.4 17.0 1.7 1 1 1 2 2 2 0 Prominin Dynamin_N PF00350.23 OWF44506.1 - 1.2 9.1 21.0 0.35 10.9 0.4 4.2 3 1 0 3 3 2 0 Dynamin family V_ATPase_I PF01496.19 OWF44506.1 - 1.6 6.6 10.1 2.1 6.1 10.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apolipoprotein PF01442.18 OWF44506.1 - 1.7 8.5 16.8 5.9 6.7 16.8 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.18 OWF44506.1 - 2.1 8.4 20.2 0.28 11.2 5.1 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) AAA_11 PF13086.6 OWF44506.1 - 5.3 6.8 14.3 3.7 7.3 12.2 1.8 2 0 0 2 2 2 0 AAA domain ALMT PF11744.8 OWF44506.1 - 5.8 5.6 12.8 7.7 5.2 12.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HU-CCDC81_bac_2 PF18175.1 OWF44506.1 - 5.9 6.8 8.5 9.2 6.2 0.5 3.9 3 1 0 4 4 4 0 CCDC81-like prokaryotic HU domain 2 Tn7_Tnp_TnsA_C PF08721.11 OWF44506.1 - 7.2 7.3 9.1 1.7 9.3 1.3 3.3 2 2 2 4 4 2 0 TnsA endonuclease C terminal Gamma_PGA_hydro PF05908.11 OWF44507.1 - 0.00015 21.3 0.7 0.00061 19.2 0.2 1.9 1 1 1 2 2 2 1 Poly-gamma-glutamate hydrolase UNC-79 PF14776.6 OWF44507.1 - 0.055 12.2 0.5 0.064 12.0 0.5 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF4484 PF14831.6 OWF44507.1 - 0.071 13.2 2.9 0.083 12.9 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Myc_N PF01056.18 OWF44507.1 - 1.3 8.9 7.0 1.6 8.6 7.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 OWF44507.1 - 1.6 6.9 6.2 1.6 6.9 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OWF44507.1 - 5 5.1 11.5 5 5.1 11.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 OWF44507.1 - 6.1 6.6 9.0 8.8 6.1 9.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PAC1 PF16094.5 OWF44507.1 - 6.3 5.9 7.3 8.5 5.4 7.3 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 AIG1 PF04548.16 OWF44508.1 - 1.8e-64 217.0 0.0 1.8e-64 217.0 0.0 2.3 1 1 1 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 OWF44508.1 - 3.9e-07 30.1 0.2 1.2e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF44508.1 - 6.3e-05 22.9 0.2 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OWF44508.1 - 0.0086 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OWF44508.1 - 0.018 14.5 0.3 1.2 8.6 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region FapA PF03961.13 OWF44508.1 - 0.082 11.5 20.0 0.03 12.9 17.1 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4407 PF14362.6 OWF44508.1 - 0.21 10.9 19.3 0.33 10.2 19.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_22 PF13401.6 OWF44508.1 - 0.38 11.0 10.0 0.41 10.9 0.3 4.0 3 1 1 4 4 4 0 AAA domain ABC_tran PF00005.27 OWF44508.1 - 0.46 11.0 0.0 0.46 11.0 0.0 2.9 2 1 0 2 2 1 0 ABC transporter Dynamin_N PF00350.23 OWF44508.1 - 2.5 8.1 20.1 1.7 8.7 0.3 4.0 2 2 0 3 3 2 0 Dynamin family DUF4717 PF15838.5 OWF44508.1 - 2.7 8.1 0.0 2.7 8.1 0.0 3.3 3 1 0 3 3 2 0 Domain of unknown function (DUF4717) Exonuc_VII_L PF02601.15 OWF44508.1 - 2.7 7.5 11.4 4.7 6.7 11.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2514 PF10721.9 OWF44508.1 - 5.9 6.9 11.6 6.2 6.8 9.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) V_ATPase_I PF01496.19 OWF44508.1 - 6.9 4.5 17.6 9.4 4.0 17.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AIG1 PF04548.16 OWF44509.1 - 9.9e-66 221.1 0.1 9.9e-66 221.1 0.1 2.2 1 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF44509.1 - 1.8e-08 34.4 0.0 6.4e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF44509.1 - 3.4e-06 27.1 1.7 4.1e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OWF44509.1 - 0.0003 20.4 0.0 0.00072 19.1 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OWF44509.1 - 0.0036 16.8 0.1 0.62 9.6 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OWF44509.1 - 0.075 13.4 1.2 0.47 10.9 0.0 2.8 3 1 1 4 4 4 0 RNA helicase ABC_tran PF00005.27 OWF44509.1 - 0.24 11.9 0.0 0.24 11.9 0.0 2.9 2 1 0 2 2 1 0 ABC transporter V_ATPase_I PF01496.19 OWF44509.1 - 0.28 9.1 11.3 0.35 8.7 11.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF445 PF04286.12 OWF44509.1 - 0.29 10.9 12.6 0.47 10.2 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_22 PF13401.6 OWF44509.1 - 0.49 10.7 11.1 1.3 9.3 0.2 3.9 3 1 2 5 5 5 0 AAA domain AAA_16 PF13191.6 OWF44509.1 - 1.3 9.4 3.9 3 8.2 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain DUF4407 PF14362.6 OWF44509.1 - 2.9 7.2 16.2 5.5 6.3 16.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dynamin_N PF00350.23 OWF44509.1 - 6 6.9 19.4 1.3 9.0 0.3 4.0 2 2 1 3 3 2 0 Dynamin family GST_C_3 PF14497.6 OWF44511.1 - 3e-17 62.6 0.1 4.2e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF44511.1 - 3.3e-10 40.0 0.0 5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF44511.1 - 8e-08 32.5 0.0 1.3e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF44511.1 - 0.011 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF44511.1 - 0.011 16.2 0.0 0.077 13.4 0.0 2.3 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF44511.1 - 0.02 15.6 0.0 0.041 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF4537 PF15057.6 OWF44512.1 - 1.7e-29 102.3 0.6 2e-28 98.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) VWA_3 PF13768.6 OWF44512.1 - 4.1e-10 39.8 0.0 9.6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF44512.1 - 0.00011 22.8 0.0 0.00043 20.9 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF44512.1 - 0.00015 22.1 0.0 0.00039 20.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Toprim_2 PF13155.6 OWF44512.1 - 0.29 11.6 2.1 2.3 8.7 1.6 2.7 2 0 0 2 2 2 0 Toprim-like NOT2_3_5 PF04153.18 OWF44513.1 - 1e-30 106.5 0.4 1e-30 106.5 0.4 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MIG-14_Wnt-bd PF06664.12 OWF44515.1 - 1.4e-97 326.5 30.3 1.4e-97 326.5 30.3 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion HEPN_DZIP3 PF18738.1 OWF44516.1 - 2.5e-30 105.1 0.0 4.3e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN DUF4450 PF14614.6 OWF44516.1 - 0.023 14.3 4.3 16 5.0 0.1 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4450) DUF3022 PF11226.8 OWF44516.1 - 0.069 13.6 9.5 26 5.3 0.4 4.3 1 1 7 8 8 8 0 Protein of unknown function (DUF3022) Cauli_DNA-bind PF03310.13 OWF44516.1 - 0.45 10.6 10.4 19 5.4 0.8 4.2 1 1 3 4 4 4 0 Caulimovirus DNA-binding protein Imm7 PF15585.6 OWF44516.1 - 0.63 10.3 4.5 6.6 7.0 0.5 3.1 1 1 1 3 3 3 0 Immunity protein 7 Adeno_shaft PF00608.17 OWF44516.1 - 3.4 7.6 22.4 3.3e+02 1.3 0.0 9.6 11 0 0 11 11 11 0 Adenoviral fibre protein (repeat/shaft region) Arrestin_N PF00339.29 OWF44517.1 - 1.2e-24 87.1 0.0 2.8e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF44517.1 - 1.9e-17 64.0 0.0 2.2e-15 57.3 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 OWF44517.1 - 0.0009 18.3 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 OWF44517.1 - 0.002 17.4 0.7 0.0034 16.6 0.2 1.6 2 0 0 2 2 2 1 Rgp1 LDB19 PF13002.7 OWF44517.1 - 0.064 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like HCR PF07111.12 OWF44518.1 - 8.3e-53 179.6 68.1 2.2e-52 178.2 68.1 1.6 1 1 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) Seryl_tRNA_N PF02403.22 OWF44518.1 - 0.02 15.1 3.1 0.02 15.1 3.1 7.4 4 3 5 9 9 9 0 Seryl-tRNA synthetase N-terminal domain WD40_alt PF14077.6 OWF44518.1 - 4.7 7.2 10.8 35 4.4 0.1 5.3 5 0 0 5 5 5 0 Alternative WD40 repeat motif Pox_A_type_inc PF04508.12 OWF44518.1 - 6.6 6.8 18.0 6.1 6.9 0.1 6.2 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat CRF PF00473.17 OWF44520.1 - 2.5 8.2 10.3 3.7e+03 -1.9 10.3 3.5 1 1 0 1 1 1 0 Corticotropin-releasing factor family DUF3523 PF12037.8 OWF44520.1 - 3.2 7.0 8.6 3.6 6.9 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Radial_spoke_3 PF06098.11 OWF44522.1 - 0.048 12.9 14.7 0.82 8.9 7.3 2.1 1 1 1 2 2 2 0 Radial spoke protein 3 UBA PF00627.31 OWF44522.1 - 0.053 13.4 5.5 21 5.2 0.1 5.5 4 1 1 5 5 5 0 UBA/TS-N domain DUF4644 PF15486.6 OWF44522.1 - 1.1 9.0 7.8 3.5 7.4 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4644) Alanine_zipper PF11839.8 OWF44522.1 - 9.2 6.7 13.2 15 6.1 3.0 3.3 2 2 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein Ribosomal_L28e PF01778.17 OWF44522.1 - 9.6 7.0 9.5 2.7 8.8 3.6 2.4 1 1 1 2 2 2 0 Ribosomal L28e protein family UBA PF00627.31 OWF44524.1 - 0.041 13.8 2.9 20 5.2 0.0 4.6 3 1 1 4 4 4 0 UBA/TS-N domain T7SS_ESX_EspC PF10824.8 OWF44524.1 - 1.6 9.2 21.0 2.7 8.5 5.0 2.9 1 1 2 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Radial_spoke_3 PF06098.11 OWF44524.1 - 2.5 7.3 16.7 3.6 6.8 8.8 2.3 1 1 1 2 2 2 0 Radial spoke protein 3 Phospholamban PF04272.14 OWF44524.1 - 7 6.2 7.7 44 3.6 0.1 4.5 2 1 4 6 6 6 0 Phospholamban Mtp PF03821.16 OWF44525.1 - 0.035 13.7 3.6 0.041 13.5 3.6 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter MscS_porin PF12795.7 OWF44525.1 - 0.11 12.1 0.1 7.4 6.0 0.0 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF3447 PF11929.8 OWF44525.1 - 0.18 11.8 0.1 29 4.7 0.0 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) TOM6p PF15184.6 OWF44525.1 - 0.32 10.8 1.7 14 5.5 0.1 3.4 1 1 1 3 3 3 0 Mitochondrial import receptor subunit TOM6 homolog TFB6 PF17110.5 OWF44525.1 - 0.98 9.1 10.1 24 4.6 0.8 3.7 1 1 2 3 3 3 0 Subunit 11 of the general transcription factor TFIIH TauD PF02668.16 OWF44526.1 - 3.3e-37 128.7 1.0 4.9e-37 128.2 1.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OWF44526.1 - 4.3e-12 46.5 3.1 5.2e-12 46.2 0.3 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF971) DUF1720 PF08226.11 OWF44527.1 - 2.7e-12 46.9 29.3 1.8e+04 -7.5 29.3 7.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) DUF4119 PF13494.6 OWF44527.1 - 2.1e-08 34.2 28.2 20 5.4 0.8 10.6 1 1 8 9 9 9 8 Domain of unknown function, B. Theta Gene description (DUF4119) Speriolin_N PF15058.6 OWF44527.1 - 1.4e-06 28.6 0.0 1.5 8.8 0.0 5.3 1 1 0 1 1 1 1 Speriolin N terminus DUF4257 PF14074.6 OWF44527.1 - 0.004 17.3 26.6 32 4.8 0.1 13.4 1 1 4 5 5 5 1 Protein of unknown function (DUF4257) Drf_FH1 PF06346.12 OWF44528.1 - 0.12 12.1 0.2 7.7 6.2 0.2 2.3 1 1 1 2 2 2 0 Formin Homology Region 1 CDRT4 PF15213.6 OWF44528.1 - 0.12 13.0 0.5 17 6.0 0.1 3.1 2 1 1 3 3 3 0 CMT1A duplicated region transcript 4 protein DUF4898 PF16239.5 OWF44529.1 - 9.2 6.3 14.2 30 4.6 0.4 4.2 1 1 4 5 5 5 0 Domain of unknown function (DUF4898) Tctex-1 PF03645.13 OWF44530.1 - 7.8e-24 83.9 3.0 1.4e-23 83.1 3.0 1.4 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_L13 PF00572.18 OWF44531.1 - 4.4e-11 43.1 1.2 2.8e-09 37.3 0.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 Morc6_S5 PF17942.1 OWF44532.1 - 1.5e-33 115.8 0.2 3.9e-33 114.4 0.2 1.8 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 OWF44532.1 - 2e-15 56.5 8.6 5.2e-15 55.2 8.6 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger Acyl-CoA_dh_2 PF08028.11 OWF44532.1 - 0.99 9.7 4.4 2.8 8.2 4.4 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Alanine_zipper PF11839.8 OWF44532.1 - 9 6.7 18.4 11 6.5 10.4 2.8 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein EXS PF03124.14 OWF44533.1 - 3e-16 59.7 0.6 3.6e-16 59.4 0.6 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 OWF44534.1 - 1.9e-14 54.4 5.4 3.4e-14 53.6 5.4 1.4 1 1 0 1 1 1 1 SPX domain PDZ PF00595.24 OWF44535.1 - 3.5e-08 33.7 0.0 1.2e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 PDZ domain Sen15 PF09631.10 OWF44536.1 - 1.2e-23 83.3 0.0 1.8e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Sen15 protein Sec34 PF04136.15 OWF44536.1 - 0.036 14.0 0.2 0.061 13.2 0.2 1.4 1 0 0 1 1 1 0 Sec34-like family zf-RING_2 PF13639.6 OWF44537.1 - 1.2e-10 41.6 3.1 2.7e-10 40.4 3.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF44537.1 - 1.3e-10 40.8 2.5 2.8e-10 39.8 2.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF44537.1 - 1.5e-08 34.3 3.7 3.5e-08 33.2 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF44537.1 - 1.7e-08 34.4 3.8 5.5e-08 32.7 3.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF44537.1 - 2.3e-07 30.6 3.7 5.5e-07 29.3 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF44537.1 - 2.5e-07 30.9 6.5 1.5e-06 28.3 6.5 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF44537.1 - 4.9e-05 23.2 2.3 0.00013 21.9 2.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF44537.1 - 0.0012 18.6 1.9 0.0028 17.5 1.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OWF44537.1 - 0.0015 18.3 0.5 0.003 17.4 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OWF44537.1 - 0.0023 17.5 3.2 0.0057 16.3 3.2 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OWF44537.1 - 0.0027 17.5 2.3 0.0078 16.0 2.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 OWF44537.1 - 0.015 15.6 1.3 0.046 14.0 1.3 1.9 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 OWF44537.1 - 0.028 14.4 4.0 0.18 11.9 4.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF442 PF04273.13 OWF44537.1 - 0.16 12.0 0.8 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) RINGv PF12906.7 OWF44537.1 - 0.18 12.0 4.2 0.091 12.9 1.2 2.1 2 1 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 OWF44537.1 - 0.61 10.3 3.5 1.5 9.1 3.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ADP_ribosyl_GH PF03747.14 OWF44538.1 - 1e-23 84.5 0.0 1.2e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Phage_tail_3 PF08813.11 OWF44538.1 - 0.0047 16.6 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Phage tail tube protein, TTP Ank_5 PF13857.6 OWF44539.1 - 1.1e-13 51.1 1.0 1.2e-07 31.9 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF44539.1 - 1.4e-13 51.1 0.0 1.7e-09 38.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF44539.1 - 2.6e-12 47.2 0.2 3.8e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF44539.1 - 2.9e-11 43.3 2.5 2.1e-05 24.7 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OWF44539.1 - 1.2e-08 34.5 0.3 0.0089 16.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat EF-hand_1 PF00036.32 OWF44540.1 - 8.3e-25 84.4 7.2 2e-07 30.1 0.2 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 OWF44540.1 - 1.3e-22 80.0 10.6 1.6e-15 57.3 1.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF44540.1 - 1.6e-22 77.5 6.8 8.8e-06 25.3 0.0 5.7 4 1 2 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 OWF44540.1 - 1.1e-20 72.1 7.2 1e-06 28.0 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF44540.1 - 2.8e-18 65.5 3.1 4.7e-06 26.3 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF44540.1 - 4.2e-07 30.3 0.8 0.2 12.0 0.0 3.3 3 1 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF44540.1 - 0.00025 21.0 3.8 0.43 10.6 0.4 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF44540.1 - 0.0076 16.6 0.3 0.15 12.4 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 OWF44540.1 - 0.016 15.2 3.1 26 4.7 0.0 3.7 3 1 1 4 4 4 0 Caleosin related protein EF-hand_13 PF17958.1 OWF44540.1 - 0.12 12.2 0.1 2.3 8.1 0.0 2.8 2 2 0 2 2 2 0 EF-hand domain S10_plectin PF03501.15 OWF44540.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.6 1 1 0 1 1 1 0 Plectin/S10 domain 7tm_1 PF00001.21 OWF44541.1 - 1.4e-52 178.7 22.4 1.4e-52 178.7 22.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF44541.1 - 2.8e-15 56.4 21.5 3.7e-15 56.0 21.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF44541.1 - 2.6e-06 27.3 33.3 5.5e-06 26.2 30.4 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TFIID_NTD2 PF04494.15 OWF44542.1 - 0.097 12.9 14.9 2.9 8.1 0.1 4.2 1 1 3 4 4 4 0 WD40 associated region in TFIID subunit, NTD2 domain Ribosomal_L22e PF01776.17 OWF44542.1 - 6 7.3 15.1 8.6 6.8 0.2 4.3 1 1 3 4 4 4 0 Ribosomal L22e protein family Fibrinogen_BP PF08017.11 OWF44543.1 - 0.0018 16.8 0.1 0.0021 16.5 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein p450 PF00067.22 OWF44545.1 - 2.1e-36 125.7 0.0 2e-26 92.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Apolipoprotein PF01442.18 OWF44546.1 - 3.1e-05 23.9 0.8 3.8e-05 23.6 0.8 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HisKA_3 PF07730.13 OWF44546.1 - 0.00022 21.7 3.7 0.0026 18.2 1.8 2.1 1 1 1 2 2 2 2 Histidine kinase Tektin PF03148.14 OWF44546.1 - 0.0037 16.1 0.3 0.0043 15.9 0.3 1.1 1 0 0 1 1 1 1 Tektin family Baculo_PEP_C PF04513.12 OWF44546.1 - 0.0043 17.1 0.4 0.0059 16.6 0.4 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 OWF44546.1 - 0.0044 17.6 3.0 0.062 13.9 2.9 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) DUF2397 PF09660.10 OWF44546.1 - 0.0066 15.4 0.3 0.0082 15.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) DUF1664 PF07889.12 OWF44546.1 - 0.0072 16.4 0.1 0.0095 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CorA PF01544.18 OWF44546.1 - 0.0097 15.3 0.6 0.011 15.1 0.6 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ntox28 PF15605.6 OWF44546.1 - 0.018 15.3 1.7 0.025 14.8 0.8 1.6 1 1 1 2 2 2 0 Bacterial toxin 28 Syntaxin-6_N PF09177.11 OWF44546.1 - 0.026 15.0 0.3 0.036 14.6 0.3 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF1043 PF06295.12 OWF44546.1 - 0.029 14.4 2.7 0.45 10.5 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DegS PF05384.11 OWF44546.1 - 0.052 13.0 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Sensor protein DegS SlyX PF04102.12 OWF44546.1 - 0.067 13.8 2.3 0.57 10.8 1.7 2.0 1 1 1 2 2 2 0 SlyX OmpH PF03938.14 OWF44546.1 - 0.067 13.5 0.0 0.086 13.2 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5082 PF16888.5 OWF44546.1 - 0.077 13.3 0.5 0.13 12.6 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF5329 PF17263.2 OWF44546.1 - 0.09 13.0 0.2 12 6.2 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5329) HTH_30 PF13556.6 OWF44546.1 - 0.12 12.2 6.9 1 9.2 4.6 2.5 1 1 2 3 3 3 0 PucR C-terminal helix-turn-helix domain Prominin PF05478.11 OWF44546.1 - 0.13 10.2 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Prominin Helo_like_N PF17111.5 OWF44546.1 - 0.45 9.8 2.0 1.3 8.4 0.8 1.8 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Apolipoprotein PF01442.18 OWF44547.1 - 1.4e-05 25.0 1.9 1.8e-05 24.7 1.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Tektin PF03148.14 OWF44547.1 - 0.00019 20.3 0.6 0.00022 20.1 0.6 1.1 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.12 OWF44547.1 - 0.00022 21.3 0.1 0.00027 20.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) HisKA_3 PF07730.13 OWF44547.1 - 0.0013 19.2 4.8 0.14 12.7 2.1 2.2 1 1 1 2 2 2 2 Histidine kinase Baculo_PEP_C PF04513.12 OWF44547.1 - 0.0014 18.6 0.3 0.002 18.2 0.3 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2397 PF09660.10 OWF44547.1 - 0.0017 17.4 0.1 0.0019 17.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) DUF883 PF05957.13 OWF44547.1 - 0.0087 16.6 4.2 0.87 10.2 0.3 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) CorA PF01544.18 OWF44547.1 - 0.019 14.3 1.1 0.023 14.0 1.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ApoLp-III PF07464.11 OWF44547.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 OWF44547.1 - 0.023 12.7 0.2 0.026 12.5 0.2 1.1 1 0 0 1 1 1 0 Prominin RmuC PF02646.16 OWF44547.1 - 0.027 13.6 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 RmuC family Syntaxin-6_N PF09177.11 OWF44547.1 - 0.027 15.0 0.5 0.04 14.5 0.5 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal HrpB7 PF09486.10 OWF44547.1 - 0.028 14.8 2.4 0.04 14.3 2.4 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Mis12 PF05859.12 OWF44547.1 - 0.035 14.2 0.4 0.048 13.7 0.4 1.1 1 0 0 1 1 1 0 Mis12 protein Helo_like_N PF17111.5 OWF44547.1 - 0.041 13.2 1.5 0.054 12.8 1.5 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF4455 PF14643.6 OWF44547.1 - 0.043 12.5 0.9 0.053 12.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Lectin_N PF03954.14 OWF44547.1 - 0.048 13.4 1.3 0.12 12.1 1.3 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4795 PF16043.5 OWF44547.1 - 0.052 13.1 0.3 0.067 12.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) AAA_32 PF13654.6 OWF44547.1 - 0.06 12.1 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Nsp1 PF11501.8 OWF44547.1 - 0.073 13.1 0.4 2.3 8.3 0.1 2.5 1 1 2 3 3 3 0 Non structural protein Nsp1 Phasin PF05597.11 OWF44547.1 - 0.073 13.1 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MT0933_antitox PF14013.6 OWF44547.1 - 0.08 13.3 0.0 0.68 10.3 0.0 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein PEP-utilisers_N PF05524.13 OWF44547.1 - 0.085 13.0 1.1 0.29 11.3 1.1 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal HisKA PF00512.25 OWF44547.1 - 0.1 12.6 4.0 0.15 12.1 4.0 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain OmpH PF03938.14 OWF44547.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ApoO PF09769.9 OWF44547.1 - 0.14 12.1 0.1 0.76 9.7 0.1 1.9 1 1 0 1 1 1 0 Apolipoprotein O DUF948 PF06103.11 OWF44547.1 - 0.19 12.0 2.6 0.34 11.2 2.6 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 OWF44547.1 - 0.23 11.7 3.5 1.5 9.1 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1043 PF06295.12 OWF44547.1 - 0.27 11.2 5.5 1.7 8.7 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Vac_Fusion PF02346.16 OWF44547.1 - 0.39 10.4 5.0 0.52 10.0 1.5 2.2 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 IL17 PF06083.11 OWF44548.1 - 1.2e-16 61.0 8.3 1.7e-16 60.5 8.3 1.2 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 OWF44549.1 - 9.9e-15 54.8 5.0 2e-14 53.8 5.0 1.5 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 OWF44550.1 - 1e-14 54.8 7.0 1.9e-14 53.9 7.0 1.5 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 OWF44551.1 - 7.9e-14 51.9 7.2 2e-13 50.6 7.2 1.7 1 0 0 1 1 1 1 Interleukin-17 An_peroxidase PF03098.15 OWF44552.1 - 1e-178 595.2 0.0 1.2e-178 595.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 OWF44553.1 - 1.1e-165 552.2 0.0 1.3e-165 552.0 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase C2-C2_1 PF11618.8 OWF44553.1 - 0.026 14.6 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 An_peroxidase PF03098.15 OWF44554.1 - 8.1e-166 552.7 0.0 1.1e-165 552.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Glyco_transf_7N PF13733.6 OWF44555.1 - 3.7e-52 175.5 0.5 6.8e-52 174.7 0.5 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF44555.1 - 7.6e-31 105.6 0.3 1.5e-30 104.7 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF44555.1 - 0.0087 15.6 0.0 0.092 12.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 AAA_12 PF13087.6 OWF44555.1 - 0.054 13.1 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 OWF44557.1 - 6.5e-13 49.0 0.1 3.4e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF44557.1 - 9.7e-13 48.4 0.2 1e-11 45.0 0.1 2.3 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Death PF00531.22 OWF44557.1 - 4.5e-10 39.6 0.0 3.1e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 Death domain Arf PF00025.21 OWF44557.1 - 4.3e-05 23.0 0.0 0.0055 16.2 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 OWF44557.1 - 0.0029 17.2 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_18 PF13238.6 OWF44557.1 - 0.0048 17.4 0.0 0.016 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OWF44557.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OWF44557.1 - 0.026 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OWF44557.1 - 0.044 14.0 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF44557.1 - 0.064 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 OWF44557.1 - 0.084 12.5 0.1 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OWF44557.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Clc-like PF07062.12 OWF44558.1 - 5.9e-06 25.9 0.4 5.9e-06 25.9 0.4 1.4 2 0 0 2 2 2 1 Clc-like PMP22_Claudin PF00822.20 OWF44558.1 - 8.1e-06 25.8 1.7 9.8e-06 25.5 1.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF44558.1 - 0.0084 15.9 0.6 0.0084 15.9 0.6 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Wzz PF02706.15 OWF44558.1 - 1.2 9.5 3.6 10 6.5 0.7 2.2 2 0 0 2 2 2 0 Chain length determinant protein CopD PF05425.13 OWF44558.1 - 7.7 7.0 11.0 0.16 12.4 1.9 2.1 2 0 0 2 2 2 0 Copper resistance protein D Fibrinogen_C PF00147.18 OWF44559.1 - 2.7e-23 82.9 2.2 3e-23 82.8 2.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF44560.1 - 2.3e-32 112.6 1.0 2.4e-32 112.5 1.0 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF44561.1 - 9.3e-58 195.6 2.2 1.2e-57 195.3 2.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Zincin_1 PF06262.11 OWF44563.1 - 2.8e-07 30.5 37.4 18 5.5 0.1 12.0 3 3 14 17 17 17 14 Zincin-like metallopeptidase Phage_CI_repr PF07022.13 OWF44563.1 - 2.6e-05 24.2 13.4 43 4.3 0.0 10.2 3 3 12 16 16 16 1 Bacteriophage CI repressor helix-turn-helix domain Drf_FH1 PF06346.12 OWF44563.1 - 6.4e-05 22.7 0.0 0.38 10.5 0.0 4.0 1 1 0 3 3 3 2 Formin Homology Region 1 YccJ PF13993.6 OWF44564.1 - 0.026 14.9 0.0 21 5.6 0.0 4.5 2 2 1 5 5 5 0 YccJ-like protein HP_OMP PF01856.17 OWF44564.1 - 0.026 14.6 0.9 0.83 9.7 0.9 3.1 1 1 0 1 1 1 0 Helicobacter outer membrane protein DUF1951 PF09188.10 OWF44564.1 - 0.044 13.8 0.7 20 5.2 0.0 4.1 1 1 6 7 7 7 0 Domain of unknown function (DUF1951) DUF4535 PF15054.6 OWF44564.1 - 0.39 10.5 11.6 1.5e+02 2.2 0.1 7.2 6 2 1 7 7 7 0 Domain of unknown function (DUF4535) RTT107_BRCT_5 PF16770.5 OWF44564.1 - 3.5 7.6 4.9 12 5.9 0.1 3.9 1 1 2 5 5 5 0 Regulator of Ty1 transposition protein 107 BRCT domain YdjM PF04307.14 OWF44565.1 - 0.00014 21.2 17.3 1.8e+04 -9.3 17.3 10.7 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase PreAtp-grasp PF18604.1 OWF44565.1 - 0.00018 21.2 0.4 64 3.2 0.0 6.6 1 1 6 9 9 9 1 Pre ATP-grasp domain PAAR_motif PF05488.13 OWF44566.1 - 4.6e-21 74.8 1.0 0.048 13.8 0.0 10.8 2 1 3 6 6 6 6 PAAR motif NIR_SIR_ferr PF03460.17 OWF44566.1 - 0.024 14.5 21.0 21 5.0 0.0 11.7 7 5 6 14 14 14 0 Nitrite/Sulfite reductase ferredoxin-like half domain MFS_1 PF07690.16 OWF44567.1 - 9e-05 21.6 4.6 0.00012 21.1 4.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Arf PF00025.21 OWF44568.1 - 6.3e-15 55.1 0.0 7.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF44568.1 - 0.00021 20.8 0.1 0.0005 19.5 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OWF44568.1 - 0.00095 18.9 0.0 0.12 12.1 0.0 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 OWF44568.1 - 0.0011 19.1 0.0 0.0029 17.8 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OWF44568.1 - 0.0043 17.6 0.3 0.0097 16.4 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OWF44568.1 - 0.0044 16.7 0.6 0.01 15.6 0.2 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF44568.1 - 0.0046 17.5 0.1 0.0088 16.6 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 OWF44568.1 - 0.0047 17.3 0.0 0.0094 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 OWF44568.1 - 0.0053 16.0 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_15 PF13175.6 OWF44568.1 - 0.0059 16.4 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OWF44568.1 - 0.0062 16.5 0.1 0.018 15.0 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_21 PF13304.6 OWF44568.1 - 0.0079 16.0 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 OWF44568.1 - 0.0081 15.5 0.2 0.019 14.3 0.1 1.6 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 OWF44568.1 - 0.013 15.0 0.4 0.028 13.9 0.2 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 OWF44568.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OWF44568.1 - 0.019 14.9 0.2 0.35 10.8 0.2 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 OWF44568.1 - 0.039 13.5 0.1 0.088 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OWF44568.1 - 0.051 13.9 0.0 0.091 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OWF44568.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 OWF44568.1 - 0.13 11.6 0.3 0.31 10.4 0.3 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family KAP_NTPase PF07693.14 OWF44568.1 - 0.13 11.4 0.1 0.3 10.3 0.1 1.6 1 1 1 2 2 2 0 KAP family P-loop domain Septin PF00735.18 OWF44568.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin DLIC PF05783.11 OWF44568.1 - 0.19 10.5 0.3 0.27 10.0 0.3 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SWIM PF04434.17 OWF44569.1 - 0.012 15.3 3.0 0.025 14.3 3.0 1.6 1 0 0 1 1 1 0 SWIM zinc finger Ribosomal_S11 PF00411.19 OWF44570.1 - 8.5e-37 125.9 0.5 1.1e-36 125.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 OWF44570.1 - 0.041 14.1 0.0 0.082 13.2 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Ribosomal_L18p PF00861.22 OWF44570.1 - 0.13 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Sec7 PF01369.20 OWF44571.1 - 3.9e-42 144.0 0.4 8.4e-42 142.9 0.2 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 OWF44571.1 - 1.5e-41 141.5 1.1 3.6e-41 140.3 0.1 2.3 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.29 OWF44571.1 - 2.7e-08 34.3 0.7 8.3e-08 32.7 0.1 2.2 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 OWF44571.1 - 0.094 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region GRDP-like PF07173.12 OWF44571.1 - 0.27 11.9 0.1 0.27 11.9 0.1 3.0 3 0 0 3 3 3 0 Glycine-rich domain-containing protein-like Pyridoxal_deC PF00282.19 OWF44572.1 - 7.8e-22 77.5 0.0 1.7e-21 76.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OWF44572.1 - 7.1e-09 35.1 0.0 4.1e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OWF44572.1 - 2.7e-05 23.5 0.0 7.4e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OWF44572.1 - 0.001 17.7 0.0 0.0018 16.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OWF44572.1 - 0.0059 16.0 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OWF44572.1 - 0.071 12.4 0.1 0.24 10.6 0.1 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 OWF44572.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RNA_pol_Rpb1_R PF05001.13 OWF44572.1 - 0.41 11.1 19.8 0.064 13.6 2.5 3.7 3 1 0 3 3 3 0 RNA polymerase Rpb1 C-terminal repeat Ank_2 PF12796.7 OWF44573.1 - 5.1e-13 49.4 0.1 8.7e-09 35.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF44573.1 - 8.5e-09 35.5 0.1 5e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF44573.1 - 2.3e-07 30.9 0.0 0.032 14.7 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OWF44573.1 - 2.9e-07 30.9 0.0 6.4e-06 26.6 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44573.1 - 0.0019 18.5 0.0 0.16 12.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat SGTA_dimer PF16546.5 OWF44574.1 - 2.3e-06 27.3 0.1 76 3.2 0.0 9.2 6 5 6 12 12 12 0 Homodimerisation domain of SGTA DUF2110 PF09883.9 OWF44574.1 - 0.081 12.5 0.0 19 4.7 0.0 4.1 2 1 2 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2110) HHH PF00633.23 OWF44574.1 - 3.5 7.7 0.0 3.5 7.7 0.0 8.4 11 0 0 11 11 11 0 Helix-hairpin-helix motif BAMBI PF06211.12 OWF44575.1 - 0.068 13.4 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain AOC_like PF18678.1 OWF44575.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain Ets PF00178.22 OWF44576.1 - 8.8e-32 109.4 2.4 1.6e-31 108.6 2.4 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 OWF44576.1 - 2.1e-19 69.2 0.6 4.7e-19 68.1 0.6 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain IgGFc_binding PF17517.2 OWF44579.1 - 2.3e-17 63.2 1.1 3.5e-17 62.6 0.6 1.5 2 0 0 2 2 2 1 IgGFc binding protein Cu-binding_MopE PF11617.8 OWF44579.1 - 0.15 12.3 7.8 0.047 13.9 1.7 2.4 2 0 0 2 2 2 0 Putative metal-binding motif DUF927 PF06048.11 OWF44580.1 - 0.0046 16.6 0.2 1.6 8.2 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF927) DUF4573 PF15140.6 OWF44581.1 - 6.4e-09 35.9 12.9 4.1e-05 23.5 5.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Amelogenin PF02948.15 OWF44581.1 - 9.2 6.9 35.3 1.8e+04 -10.1 35.3 2.9 1 1 0 1 1 1 0 Amelogenin Alpha_L_fucos PF01120.17 OWF44583.1 - 1.9e-21 76.9 0.0 2.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Alpha_L_fucos PF01120.17 OWF44584.1 - 3.5e-119 398.4 5.0 4.8e-119 397.9 5.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF44584.1 - 7.7e-15 55.2 0.1 1.4e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 OWF44584.1 - 0.085 13.0 0.1 0.47 10.6 0.0 2.1 1 1 1 2 2 2 0 Lactococcus bacteriophage putative transcription regulator Chalcone_3 PF16036.5 OWF44585.1 - 0.034 14.3 0.4 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Chalcone isomerase-like DUF2052 PF09747.9 OWF44585.1 - 0.13 12.4 1.5 0.2 11.7 1.5 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) IGFBP PF00219.18 OWF44587.1 - 1.2e-06 29.1 19.6 2.4e-06 28.1 19.6 1.5 1 0 0 1 1 1 1 Insulin-like growth factor binding protein Glyco_hydro_31 PF01055.26 OWF44588.1 - 2.1e-55 188.7 2.2 3.5e-55 188.0 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Colipase_C PF02740.14 OWF44589.1 - 0.009 16.2 5.5 0.019 15.1 3.4 2.3 1 1 1 2 2 2 1 Colipase, C-terminal domain Prokineticin PF06607.11 OWF44589.1 - 0.014 15.7 6.7 0.066 13.5 6.6 2.0 1 1 0 1 1 1 0 Prokineticin Uds1 PF15456.6 OWF44589.1 - 0.26 11.5 0.0 0.37 11.0 0.0 1.1 1 0 0 1 1 1 0 Up-regulated During Septation SNF PF00209.18 OWF44590.1 - 3.3e-204 679.4 34.4 6.2e-204 678.5 34.4 1.4 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Integrin_B_tail PF07965.12 OWF44591.1 - 7.6e-16 58.4 5.5 7.6e-16 58.4 5.5 2.5 2 1 1 3 3 3 1 Integrin beta tail domain EGF_2 PF07974.13 OWF44591.1 - 1e-10 41.8 76.4 0.0004 20.7 6.5 5.5 5 0 0 5 5 5 4 EGF-like domain I-EGF_1 PF18372.1 OWF44591.1 - 0.00021 21.3 63.0 0.00028 20.9 3.3 5.3 5 0 0 5 5 5 4 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 OWF44591.1 - 0.011 15.7 6.1 0.011 15.7 6.1 5.4 4 1 0 4 4 4 0 Tenascin EGF domain Laminin_EGF PF00053.24 OWF44591.1 - 0.031 14.4 3.3 0.031 14.4 3.3 5.9 2 1 2 4 4 4 0 Laminin EGF domain S-methyl_trans PF02574.16 OWF44592.1 - 7.9e-32 111.1 0.0 1e-31 110.8 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Redoxin PF08534.10 OWF44592.1 - 0.0007 19.3 0.0 0.2 11.3 0.0 2.7 2 1 0 2 2 2 2 Redoxin ZapB PF06005.12 OWF44593.1 - 0.22 12.0 7.2 11 6.5 2.6 3.4 2 1 0 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 OWF44593.1 - 0.52 10.2 5.7 3.6 7.5 0.4 3.5 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 OWF44593.1 - 1.2 9.2 7.3 0.36 10.9 0.5 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 OWF44593.1 - 2.2 8.1 4.9 1.5 8.7 0.1 3.0 3 1 0 3 3 3 0 Septum formation initiator SlyX PF04102.12 OWF44593.1 - 9.1 7.0 9.3 4.4 8.0 0.3 3.6 4 0 0 4 4 4 0 SlyX FemAB PF02388.16 OWF44594.1 - 0.19 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 FemAB family SNF PF00209.18 OWF44595.1 - 4.3e-206 685.6 32.7 9.8e-206 684.5 32.7 1.5 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2207 PF09972.9 OWF44595.1 - 0.77 8.4 0.0 0.77 8.4 0.0 4.0 3 2 0 3 3 3 0 Predicted membrane protein (DUF2207) ADH_N_2 PF16884.5 OWF44596.1 - 1.2e-12 47.6 0.0 1.4e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OWF44597.1 - 4.2e-23 81.8 0.0 6.5e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF44597.1 - 5.7e-10 40.4 0.0 1e-09 39.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OWF44597.1 - 4.7e-08 32.9 0.1 9.1e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N_2 PF16884.5 OWF44598.1 - 1.2e-25 89.5 0.0 2.8e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OWF44598.1 - 1.2e-20 73.8 0.1 2.3e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF44598.1 - 4.2e-09 37.6 0.1 5e-08 34.1 0.0 2.5 2 1 1 3 3 3 1 Zinc-binding dehydrogenase SIS_2 PF13580.6 OWF44598.1 - 0.024 14.7 0.2 0.049 13.6 0.2 1.5 1 0 0 1 1 1 0 SIS domain ELFV_dehydrog PF00208.21 OWF44598.1 - 0.082 12.6 0.4 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM51 PF15345.6 OWF44599.1 - 0.03 14.2 0.1 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 OWF44599.1 - 0.15 13.0 0.6 0.6 11.0 0.0 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-RING_UBOX PF13445.6 OWF44600.1 - 2.4e-11 43.4 6.6 3e-11 43.1 5.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF44600.1 - 1.1e-09 38.0 10.5 1.1e-09 38.0 10.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF44600.1 - 3.5e-07 30.3 7.6 3.5e-07 30.3 7.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF44600.1 - 2.2e-06 27.5 9.3 2.2e-06 27.5 9.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF44600.1 - 2.9e-06 27.5 9.0 2.9e-06 27.5 9.0 2.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF44600.1 - 9.2e-06 25.4 9.9 9.2e-06 25.4 9.9 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF44600.1 - 1.6e-05 24.6 8.8 1.6e-05 24.6 8.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF44600.1 - 0.00049 20.2 6.3 0.00049 20.2 6.3 4.0 4 1 0 4 4 4 1 B-box zinc finger Prok-RING_4 PF14447.6 OWF44600.1 - 0.0095 15.8 8.1 0.0095 15.8 8.1 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Melibiase_C PF17801.1 OWF44600.1 - 0.13 12.3 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain zf-RING_6 PF14835.6 OWF44600.1 - 0.26 11.2 5.5 1.2 9.1 5.5 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OWF44600.1 - 2.6 7.8 11.6 2.1 8.2 8.7 2.5 2 0 0 2 2 2 0 RING-like zinc finger SH2 PF00017.24 OWF44601.1 - 2.4e-11 43.6 0.4 1.4e-10 41.1 0.1 2.7 2 0 0 2 2 2 1 SH2 domain SOCS_box PF07525.16 OWF44601.1 - 6.5e-09 36.0 0.8 1.3e-08 35.0 0.8 1.5 1 0 0 1 1 1 1 SOCS box JSRP PF15312.6 OWF44601.1 - 0.007 16.3 1.3 0.013 15.4 0.3 2.0 2 0 0 2 2 2 1 Junctional sarcoplasmic reticulum protein MRPL52 PF18699.1 OWF44601.1 - 0.028 14.6 1.1 0.08 13.1 0.0 2.4 3 0 0 3 3 3 0 Mitoribosomal protein mL52 GAPT PF11770.8 OWF44601.1 - 4.3 7.2 17.8 0.038 13.9 5.4 3.4 4 0 0 4 4 4 0 GRB2-binding adapter (GAPT) DUF2683 PF10884.8 OWF44602.1 - 2.1e-07 31.1 25.3 58 4.1 0.0 14.2 6 5 10 18 18 18 4 Protein of unknown function (DUF2683) TFCD_C PF12612.8 OWF44602.1 - 4.3 7.1 6.0 80 3.0 0.1 4.4 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal ShK PF01549.24 OWF44604.1 - 2.5e-06 27.9 10.1 3.3e-05 24.3 10.1 3.2 1 0 0 1 1 1 1 ShK domain-like Baculo_PEP_C PF04513.12 OWF44605.1 - 0.46 10.5 9.6 2.5 8.2 0.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 OWF44605.1 - 1.6 8.7 14.1 3.1 7.8 1.9 4.0 2 2 1 3 3 3 0 Apolipoprotein O AMP-binding PF00501.28 OWF44606.1 - 9.6e-64 215.5 0.0 1.2e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF44606.1 - 0.0021 19.0 0.0 0.0055 17.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.6 OWF44607.1 - 1.4e-27 97.2 0.6 2.8e-27 96.1 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OWF44607.1 - 2e-26 93.1 0.1 3.5e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF44607.1 - 6.9e-13 49.2 0.1 1.3e-12 48.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 OWF44607.1 - 1.6e-09 38.1 0.0 2.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 OWF44607.1 - 1.2e-06 28.5 0.0 0.0041 17.0 0.0 2.8 2 1 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 OWF44607.1 - 0.00013 21.7 0.1 0.00032 20.4 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PTR2 PF00854.21 OWF44608.1 - 7.8e-107 357.5 8.1 1.9e-93 313.5 1.8 2.2 2 0 0 2 2 2 2 POT family DUF4397 PF14344.6 OWF44608.1 - 1.7e-08 35.2 2.1 1e-05 26.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4397) Galactosyl_T PF01762.21 OWF44609.1 - 5.2e-45 153.7 0.1 7.3e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF44609.1 - 0.0093 15.4 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Ig_3 PF13927.6 OWF44610.1 - 3.6e-09 37.1 0.1 7.9e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF44610.1 - 4e-08 33.2 0.1 6.5e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF44610.1 - 0.00022 21.3 0.0 0.00064 19.8 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 OWF44610.1 - 0.0045 17.1 0.0 0.068 13.3 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain DED PF01335.21 OWF44610.1 - 0.018 15.4 0.1 0.042 14.1 0.0 1.6 2 0 0 2 2 2 0 Death effector domain Ig_5 PF16681.5 OWF44610.1 - 0.035 14.5 0.2 0.47 10.9 0.2 2.4 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain AGTRAP PF06396.11 OWF44611.1 - 0.02 14.7 1.1 0.029 14.2 0.4 1.5 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Claudin_2 PF13903.6 OWF44611.1 - 0.048 13.4 22.2 8.3 6.1 22.2 2.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_2 PF12679.7 OWF44611.1 - 0.14 11.5 6.0 0.22 10.7 6.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MARVEL PF01284.23 OWF44611.1 - 0.45 10.5 16.7 3.3 7.7 16.4 2.3 1 1 0 1 1 1 0 Membrane-associating domain PRA1 PF03208.19 OWF44611.1 - 2.9 7.5 7.1 4.6 6.9 7.1 1.3 1 0 0 1 1 1 0 PRA1 family protein Lectin_C PF00059.21 OWF44612.1 - 2.3e-16 60.5 0.3 2.8e-16 60.2 0.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF44612.1 - 0.00025 20.8 0.1 0.00037 20.2 0.1 1.3 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF44613.1 - 8.3e-17 61.9 0.1 2.2e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain Adeno_E3_14_5 PF04834.12 OWF44613.1 - 0.0094 16.5 0.1 0.019 15.5 0.1 1.5 1 0 0 1 1 1 1 Early E3 14.5 kDa protein FGE-sulfatase PF03781.16 OWF44613.1 - 0.015 14.9 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 UL45 PF05473.12 OWF44613.1 - 0.053 13.2 0.0 0.079 12.6 0.0 1.4 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like 7tm_1 PF00001.21 OWF44614.1 - 3.7e-32 111.7 13.0 3.7e-31 108.4 13.0 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF44614.1 - 2.1e-06 27.3 7.5 0.00029 20.3 0.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2975 PF11188.8 OWF44614.1 - 0.0071 16.2 0.6 0.0071 16.2 0.6 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2975) MutS_V PF00488.21 OWF44615.1 - 4.2e-72 242.1 0.1 8.2e-72 241.2 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OWF44615.1 - 1.1e-34 120.3 0.7 5.5e-34 118.1 0.1 2.2 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 OWF44615.1 - 1.1e-34 119.0 0.2 2.3e-34 118.0 0.2 1.5 1 0 0 1 1 1 1 MutS domain I PWWP PF00855.17 OWF44615.1 - 2.8e-17 62.9 0.8 1.3e-16 60.8 0.8 2.3 1 0 0 1 1 1 1 PWWP domain MutS_IV PF05190.18 OWF44615.1 - 6.7e-14 52.0 0.0 2.6e-13 50.1 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 OWF44615.1 - 3.6e-12 46.7 0.4 1.7e-11 44.5 0.4 2.2 1 1 0 1 1 1 1 MutS domain II Rad17 PF03215.15 OWF44615.1 - 0.083 12.8 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain Ada3 PF10198.9 OWF44617.1 - 0.2 11.8 0.2 0.54 10.4 0.0 1.7 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 adh_short PF00106.25 OWF44618.1 - 4.5e-51 173.1 0.0 5.6e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF44618.1 - 7.2e-33 114.1 0.0 9.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF44618.1 - 5.4e-10 39.5 0.1 7.9e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OWF44618.1 - 0.00063 19.2 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OWF44618.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF745 PF05335.13 OWF44620.1 - 0.011 15.5 4.6 0.011 15.5 4.6 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF745) RNase_H_2 PF13482.6 OWF44620.1 - 0.34 10.9 1.6 1.4 8.9 0.2 2.5 3 0 0 3 3 3 0 RNase_H superfamily COG2 PF06148.11 OWF44620.1 - 0.92 9.6 8.7 1.1 9.4 3.0 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cnn_1N PF07989.11 OWF44620.1 - 1.8 8.8 18.0 0.78 9.9 2.3 4.2 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 HMMR_C PF15908.5 OWF44621.1 - 2.2e-05 24.7 5.4 2.2e-05 24.7 5.4 2.5 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor C-terminal bZIP_1 PF00170.21 OWF44621.1 - 0.025 14.6 3.7 0.025 14.6 3.7 3.1 4 0 0 4 4 4 0 bZIP transcription factor DUF948 PF06103.11 OWF44621.1 - 0.25 11.6 3.6 0.42 10.9 0.9 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SOGA PF11365.8 OWF44621.1 - 0.86 10.8 12.8 0.11 13.6 1.6 3.8 4 0 0 4 4 4 0 Protein SOGA DUF4298 PF14131.6 OWF44621.1 - 1 9.4 6.0 0.35 10.9 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Phage_GP20 PF06810.11 OWF44621.1 - 2.7 7.8 12.9 0.22 11.3 0.9 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF573 PF04504.14 OWF44621.1 - 3.1 8.5 13.2 2.3 8.9 1.8 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF573 YabA PF06156.13 OWF44621.1 - 5.3 7.7 15.7 0.32 11.7 5.6 3.1 2 1 1 3 3 3 0 Initiation control protein YabA Ax_dynein_light PF10211.9 OWF44621.1 - 5.9 6.8 23.7 2.2 8.2 11.7 3.1 2 1 0 2 2 2 0 Axonemal dynein light chain GrpE PF01025.19 OWF44621.1 - 7.4 6.2 14.4 17 5.0 0.2 3.4 3 0 0 3 3 3 0 GrpE DUF4201 PF13870.6 OWF44622.1 - 0.011 15.5 6.7 0.25 11.1 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 OWF44622.1 - 0.016 15.8 4.4 0.17 12.5 0.0 3.3 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_GP20 PF06810.11 OWF44622.1 - 0.017 14.9 0.3 0.017 14.9 0.3 2.8 2 2 1 3 3 3 0 Phage minor structural protein GP20 DUF641 PF04859.12 OWF44622.1 - 0.021 15.2 2.7 0.16 12.3 0.7 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 OWF44622.1 - 0.028 14.5 1.0 0.028 14.5 1.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Oberon_cc PF16312.5 OWF44622.1 - 0.064 13.2 0.8 0.17 11.8 0.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of Oberon CHORD PF04968.12 OWF44622.1 - 0.096 13.4 6.5 0.37 11.6 6.5 2.1 1 1 0 1 1 1 0 CHORD TrbI_Ftype PF09677.10 OWF44622.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) THOC7 PF05615.13 OWF44622.1 - 0.48 10.7 9.0 0.056 13.7 1.1 2.9 2 1 1 3 3 3 0 Tho complex subunit 7 DUF1664 PF07889.12 OWF44622.1 - 3.4 7.7 5.2 1.7 8.7 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 OWF44622.1 - 3.7 8.1 8.5 12 6.5 2.0 3.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal CARD PF00619.21 OWF44623.1 - 6.3e-13 48.6 3.3 8.5e-13 48.2 0.0 2.5 2 0 0 2 2 2 1 Caspase recruitment domain PHM7_cyt PF14703.6 OWF44623.1 - 0.23 11.7 10.3 6.2 7.0 0.1 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4407 PF14362.6 OWF44623.1 - 2.5 7.4 6.8 5.7 6.2 6.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CARD PF00619.21 OWF44624.1 - 6.1e-06 26.2 0.1 4.8e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 Caspase recruitment domain COMM_domain PF07258.14 OWF44624.1 - 0.0028 17.7 11.1 0.04 14.0 2.4 3.3 3 0 0 3 3 3 2 COMM domain NPV_P10 PF05531.12 OWF44624.1 - 0.015 15.8 8.1 1.1 9.7 0.1 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cep57_MT_bd PF06657.13 OWF44624.1 - 0.015 15.7 10.8 2.5 8.6 0.0 3.9 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 GIT_CC PF16559.5 OWF44624.1 - 1.2 9.0 9.3 4.5 7.2 1.4 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ESCRT-II PF05871.12 OWF44624.1 - 1.4 9.2 4.8 3.5 7.9 0.1 2.8 2 1 0 2 2 2 0 ESCRT-II complex subunit DUF4407 PF14362.6 OWF44624.1 - 1.9 7.7 16.2 2 7.7 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CorA PF01544.18 OWF44624.1 - 3.2 7.0 12.6 1.6 8.0 1.0 2.5 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein CARD PF00619.21 OWF44625.1 - 5.1e-11 42.4 0.3 1.3e-10 41.2 0.3 1.7 1 0 0 1 1 1 1 Caspase recruitment domain YabA PF06156.13 OWF44625.1 - 0.01 16.5 18.2 0.018 15.7 3.5 3.2 2 1 1 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 OWF44625.1 - 0.056 13.2 21.7 1.1 9.1 3.7 3.8 2 1 1 3 3 3 0 Septum formation initiator Atg14 PF10186.9 OWF44625.1 - 0.062 12.4 12.9 0.12 11.4 12.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 OWF44625.1 - 0.079 12.2 9.6 0.17 11.1 9.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein MctB PF11382.8 OWF44625.1 - 0.083 12.6 2.0 0.61 9.7 0.0 2.3 1 1 0 2 2 2 0 Copper transport outer membrane protein, MctB Amidase_3 PF01520.18 OWF44625.1 - 0.084 13.0 0.6 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase Fmp27_WPPW PF10359.9 OWF44625.1 - 0.13 11.1 9.4 0.25 10.2 9.4 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Plk4_PB2 PF18409.1 OWF44625.1 - 0.26 12.0 7.9 0.12 13.1 4.4 2.2 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 bZIP_1 PF00170.21 OWF44625.1 - 0.4 10.8 20.8 0.25 11.5 6.9 3.2 2 1 1 3 3 3 0 bZIP transcription factor Atypical_Card PF18461.1 OWF44625.1 - 0.4 10.9 3.4 0.5 10.6 0.1 2.8 2 2 2 4 4 4 0 Atypical caspase recruitment domain DUF1664 PF07889.12 OWF44625.1 - 0.57 10.2 8.8 0.38 10.8 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 OWF44625.1 - 0.68 10.6 14.9 0.43 11.2 11.8 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IMD PF08397.11 OWF44625.1 - 0.91 8.9 12.8 2.2 7.6 12.8 1.6 1 0 0 1 1 1 0 IRSp53/MIM homology domain Jnk-SapK_ap_N PF09744.9 OWF44625.1 - 1.1 9.4 17.0 0.21 11.8 11.7 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4472 PF14739.6 OWF44625.1 - 1.1 10.0 15.4 0.32 11.7 10.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) Spectrin PF00435.21 OWF44625.1 - 1.2 9.7 13.8 2 9.0 4.9 3.3 2 1 1 3 3 3 0 Spectrin repeat Spc7 PF08317.11 OWF44625.1 - 1.2 8.0 19.9 0.079 11.8 13.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 OWF44625.1 - 1.3 6.8 7.1 2 6.2 7.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 OWF44625.1 - 1.5 8.1 10.9 0.66 9.2 7.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FapA PF03961.13 OWF44625.1 - 1.6 7.2 15.6 0.21 10.1 11.0 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A ADIP PF11559.8 OWF44625.1 - 1.7 8.7 19.5 0.14 12.2 14.5 1.7 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF4337 PF14235.6 OWF44625.1 - 2 8.5 10.3 4.3 7.4 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GrpE PF01025.19 OWF44625.1 - 2.4 7.8 16.0 0.34 10.5 11.0 2.1 2 0 0 2 2 2 0 GrpE GAS PF13851.6 OWF44625.1 - 2.6 7.4 25.1 0.55 9.5 20.9 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tho2 PF11262.8 OWF44625.1 - 3 7.0 16.7 2.1 7.5 7.7 2.7 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 HMMR_C PF15908.5 OWF44625.1 - 3.8 7.7 16.0 0.55 10.5 6.4 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal BST2 PF16716.5 OWF44625.1 - 6.4 7.4 21.2 1.9 9.1 4.2 3.3 2 2 1 3 3 3 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 OWF44625.1 - 7.1 6.8 18.6 1.3 9.2 14.0 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 OWF44625.1 - 8.6 6.7 17.5 0.2 11.9 8.2 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 Tmemb_cc2 PF10267.9 OWF44626.1 - 0.0056 15.9 3.4 0.0076 15.4 3.4 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein GIT_CC PF16559.5 OWF44626.1 - 0.0098 15.7 0.2 0.028 14.3 0.2 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor WDCP PF15390.6 OWF44626.1 - 0.079 11.3 4.2 0.82 8.0 0.2 2.0 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family Myb_DNA-bind_3 PF12776.7 OWF44626.1 - 0.11 13.5 2.4 3.7 8.6 0.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Fib_alpha PF08702.10 OWF44626.1 - 0.59 10.3 4.3 0.42 10.8 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 OWF44626.1 - 1.5 9.1 7.7 0.25 11.6 1.8 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Acyl-CoA_dh_1 PF00441.24 OWF44627.1 - 2.3e-46 157.7 0.9 3.7e-46 157.0 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OWF44627.1 - 4.3e-35 120.8 0.0 7.5e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OWF44627.1 - 2.8e-26 91.5 0.0 5.4e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF44627.1 - 3.4e-15 56.5 0.1 6e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Myosin_head PF00063.21 OWF44628.1 - 1.1e-118 397.3 0.4 7.3e-66 222.8 0.1 2.4 2 1 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 OWF44628.1 - 0.0002 20.9 1.0 0.0011 18.6 0.1 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_16 PF13191.6 OWF44628.1 - 0.0014 19.0 0.1 0.0071 16.7 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OWF44628.1 - 0.0041 17.4 0.2 0.019 15.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OWF44628.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Secretin_N_2 PF07655.13 OWF44628.1 - 1.8 9.1 8.4 20 5.8 4.6 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain LRRFIP PF09738.9 OWF44628.1 - 2.9 7.3 4.7 5.7 6.3 4.7 1.4 1 0 0 1 1 1 0 LRRFIP family DUF1700 PF08006.11 OWF44629.1 - 0.45 10.0 6.9 0.64 9.5 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) CRPA PF05745.11 OWF44629.1 - 0.47 10.5 4.2 1 9.4 4.2 1.5 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF5325 PF17259.2 OWF44629.1 - 2.8 7.9 6.9 6.1 6.8 6.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF2207 PF09972.9 OWF44629.1 - 7.3 5.2 5.8 13 4.4 5.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Dynactin_p62 PF05502.13 OWF44630.1 - 2.1e-27 96.1 16.2 2.8e-13 49.5 11.4 2.2 1 1 1 2 2 2 2 Dynactin p62 family LIM PF00412.22 OWF44630.1 - 1.4 9.2 7.4 18 5.7 4.0 2.9 2 1 0 2 2 2 0 LIM domain Elf1 PF05129.13 OWF44630.1 - 1.9 8.6 11.0 1.5 8.9 5.3 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-CHY PF05495.12 OWF44630.1 - 3.7 8.1 11.0 6.5 7.3 7.5 2.8 2 1 0 2 2 2 0 CHY zinc finger Gal-3-0_sulfotr PF06990.11 OWF44631.1 - 5.6e-19 68.3 0.7 6.8e-19 68.0 0.7 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Ig_3 PF13927.6 OWF44633.1 - 0.031 14.9 3.5 0.19 12.4 3.5 2.0 1 1 0 1 1 1 0 Immunoglobulin domain Syndecan PF01034.20 OWF44634.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain ig PF00047.25 OWF44634.1 - 0.0019 18.4 1.5 0.0043 17.2 1.5 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Glycophorin_A PF01102.18 OWF44634.1 - 0.0071 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A Orf78 PF06024.12 OWF44634.1 - 0.0096 16.2 0.1 0.027 14.8 0.0 1.7 2 0 0 2 2 2 1 Orf78 (ac78) PTP_tm PF18861.1 OWF44634.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Cytomega_TRL10 PF06084.11 OWF44634.1 - 0.02 14.9 0.9 0.061 13.3 0.9 1.9 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein Amnionless PF14828.6 OWF44634.1 - 0.022 13.6 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 OWF44634.1 - 0.045 13.3 0.3 0.31 10.6 0.3 2.0 1 1 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 OWF44634.1 - 0.14 13.1 0.0 0.36 11.8 0.0 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YqzE PF14038.6 OWF44634.1 - 0.39 10.7 2.0 0.85 9.7 2.0 1.5 1 0 0 1 1 1 0 YqzE-like protein VWD PF00094.25 OWF44635.1 - 7.9e-38 130.2 2.7 2.2e-30 106.0 0.5 2.4 2 0 0 2 2 2 2 von Willebrand factor type D domain TIL PF01826.17 OWF44635.1 - 9.2e-10 38.6 26.0 1.5e-07 31.6 8.2 4.7 4 2 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain V-set PF07686.17 OWF44636.1 - 0.019 15.1 0.2 0.04 14.1 0.2 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain NdhM PF10664.9 OWF44636.1 - 0.026 14.8 0.0 0.078 13.2 0.0 1.7 1 1 1 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M ig PF00047.25 OWF44636.1 - 0.084 13.1 0.3 0.24 11.6 0.1 1.9 2 1 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 OWF44636.1 - 0.094 13.3 0.6 0.26 11.9 0.6 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Cue1_U7BR PF18499.1 OWF44637.1 - 0.066 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Branch PF02485.21 OWF44638.1 - 2.1e-40 138.8 0.0 4e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Core-2/I-Branching enzyme C1q PF00386.21 OWF44640.1 - 4.3e-24 85.2 0.2 6.6e-24 84.5 0.2 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF44640.1 - 7.5e-05 22.6 0.2 0.00011 22.1 0.2 1.2 1 0 0 1 1 1 1 BclA C-terminal domain PA14 PF07691.12 OWF44640.1 - 0.0017 18.1 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 PA14 domain PPC PF04151.15 OWF44640.1 - 0.018 16.2 0.1 2.7 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain SusF_SusE PF16411.5 OWF44640.1 - 0.025 15.1 0.1 0.059 13.9 0.1 1.7 1 1 0 1 1 1 0 Outer membrane protein SusF_SusE Corona_nucleoca PF00937.18 OWF44640.1 - 0.04 13.0 0.1 0.05 12.6 0.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF5397 PF17375.2 OWF44640.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5397) Molybdopterin PF00384.22 OWF44640.1 - 0.1 11.5 0.5 0.42 9.5 0.5 1.8 1 1 0 1 1 1 0 Molybdopterin oxidoreductase Got1 PF04178.12 OWF44641.1 - 1.1e-35 122.4 19.3 1.9e-35 121.7 19.2 1.4 1 1 1 2 2 2 2 Got1/Sft2-like family Y_phosphatase PF00102.27 OWF44642.1 - 4.5e-76 255.5 0.2 1.4e-75 253.9 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase fn3 PF00041.21 OWF44642.1 - 6.5e-28 96.9 14.6 6.1e-08 32.9 0.2 7.3 6 1 0 6 6 6 4 Fibronectin type III domain DSPc PF00782.20 OWF44642.1 - 0.002 17.9 0.0 0.0074 16.1 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pur_ac_phosph_N PF16656.5 OWF44642.1 - 0.019 15.5 22.4 1.8 9.2 0.1 6.2 6 1 0 6 6 6 0 Purple acid Phosphatase, N-terminal domain TonB_2 PF13103.6 OWF44642.1 - 0.051 13.8 0.1 9.7 6.5 0.0 3.0 2 0 0 2 2 2 0 TonB C terminal PTPlike_phytase PF14566.6 OWF44642.1 - 0.073 13.2 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF44642.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family RhodobacterPufX PF11511.8 OWF44642.1 - 0.14 11.7 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Kazal_1 PF00050.21 OWF44643.1 - 1e-76 252.8 166.5 7e-09 35.6 6.1 12.4 6 4 6 12 12 12 12 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF44643.1 - 7e-48 160.5 213.7 8.8e-06 25.8 6.6 12.8 12 0 0 12 12 12 12 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF44644.1 - 1e-18 67.0 32.7 5e-06 26.4 11.0 3.4 1 1 2 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF44644.1 - 6.7e-17 61.3 42.8 2.3e-06 27.6 11.3 3.7 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain Metallothio_5 PF02067.15 OWF44644.1 - 1.6 8.9 43.3 0.7 10.1 7.4 3.6 2 1 1 3 3 3 0 Metallothionein family 5 BIR PF00653.21 OWF44646.1 - 2.4e-54 181.9 22.8 9.2e-20 71.1 0.3 5.4 5 0 0 5 5 5 4 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF44646.1 - 5.1e-08 32.6 17.7 5.1e-08 32.6 17.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44646.1 - 0.004 17.0 16.1 0.012 15.5 16.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 WIYLD PF10440.9 OWF44646.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Elf1 PF05129.13 OWF44646.1 - 4.5 7.4 16.4 59 3.8 0.1 3.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like CxC3 PF18804.1 OWF44647.1 - 0.057 13.3 0.4 0.078 12.8 0.4 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Sigma70_r4_2 PF08281.12 OWF44647.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 zf_ZIC PF18366.1 OWF44648.1 - 3.6e-23 81.4 10.0 3.9e-23 81.3 2.8 3.2 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 OWF44648.1 - 7.4e-18 64.1 23.2 1.4e-07 31.6 0.3 5.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 OWF44648.1 - 6.7e-16 57.8 31.2 9.5e-06 25.8 0.2 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF44648.1 - 1.4e-07 31.8 24.2 0.012 16.4 0.2 6.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OWF44648.1 - 0.24 11.5 7.3 7.8 6.6 0.6 3.4 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 OWF44648.1 - 0.32 11.1 3.5 4.3 7.5 0.0 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF44648.1 - 0.44 10.9 12.3 15 6.0 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OWF44648.1 - 0.96 9.8 14.2 0.19 12.1 5.9 3.2 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 OWF44649.1 - 5.5e-27 93.6 5.5 3.6e-26 91.0 1.2 3.1 3 0 0 3 3 2 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 OWF44649.1 - 9e-18 63.7 29.5 2.5e-05 24.5 0.1 5.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF44649.1 - 3.6e-17 61.9 25.9 1.4e-07 31.6 0.3 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF44649.1 - 1.2e-09 38.1 20.9 0.05 14.4 0.1 6.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF44649.1 - 0.024 14.9 8.5 0.13 12.5 0.9 3.4 1 1 1 3 3 3 0 C2H2-type zinc ribbon DnaI_N PF07319.11 OWF44649.1 - 0.05 14.3 0.0 0.093 13.4 0.0 1.4 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus zf-C2H2_jaz PF12171.8 OWF44649.1 - 0.1 12.9 11.9 9.7 6.6 0.1 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding EAGR_box PF16713.5 OWF44649.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box zf-C2H2_aberr PF17017.5 OWF44649.1 - 0.67 10.1 5.9 28 4.8 0.1 3.2 1 1 2 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 OWF44649.1 - 3.8 8.1 13.5 0.6 10.6 0.2 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type MGC-24 PF05283.11 OWF44649.1 - 6.2 7.3 6.8 10 6.6 0.0 2.9 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf_ZIC PF18366.1 OWF44650.1 - 4.9e-23 81.0 0.6 4.9e-23 81.0 0.6 3.6 4 1 0 4 4 4 1 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 OWF44650.1 - 2.2e-19 68.9 22.5 8.2e-08 32.4 0.3 5.0 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 OWF44650.1 - 1.3e-16 60.0 35.0 5.5e-06 26.6 0.2 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF44650.1 - 2.6e-08 34.0 29.0 0.0069 17.1 0.2 6.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF44650.1 - 0.041 13.9 3.4 2.5 8.2 0.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF44650.1 - 0.89 9.9 13.0 32 5.0 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OWF44650.1 - 1.6 9.4 18.3 17 6.1 0.0 5.1 2 2 3 5 5 5 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 OWF44650.1 - 2.3 8.4 14.3 9.3 6.4 0.1 3.8 1 1 3 4 4 4 0 Aberrant zinc-finger IgGFc_binding PF17517.2 OWF44651.1 - 6.1e-59 199.7 3.4 6.1e-59 199.7 3.4 1.6 2 0 0 2 2 2 1 IgGFc binding protein TSP_1 PF00090.19 OWF44651.1 - 1.3e-14 54.1 43.5 3.7e-07 30.3 9.8 4.4 3 1 0 3 3 3 3 Thrombospondin type 1 domain Cu-binding_MopE PF11617.8 OWF44651.1 - 2.5 8.4 11.6 0.26 11.5 2.2 2.8 2 0 0 2 2 2 0 Putative metal-binding motif IgGFc_binding PF17517.2 OWF44652.1 - 5.9e-67 226.0 3.0 9.6e-67 225.3 3.0 1.4 1 0 0 1 1 1 1 IgGFc binding protein TSP_1 PF00090.19 OWF44652.1 - 4.8e-10 39.5 45.1 0.00064 19.9 13.5 5.1 3 2 0 3 3 3 3 Thrombospondin type 1 domain TPD52 PF04201.15 OWF44653.1 - 0.0032 17.1 0.2 0.75 9.4 0.1 2.7 2 1 0 2 2 2 2 Tumour protein D52 family Tape_meas_lam_C PF09718.10 OWF44653.1 - 0.0063 16.6 2.3 4.8 7.4 0.1 4.1 2 1 3 5 5 5 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) EST1 PF10374.9 OWF44653.1 - 0.04 14.6 1.8 0.13 12.9 1.0 2.2 2 1 0 2 2 2 0 Telomerase activating protein Est1 DUF1664 PF07889.12 OWF44653.1 - 0.053 13.6 0.7 8.7 6.4 0.1 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) LPD38 PF18857.1 OWF44653.1 - 0.08 13.1 0.0 0.34 11.1 0.1 1.9 1 1 1 2 2 2 0 Large polyvalent protein associated domain 38 NPV_P10 PF05531.12 OWF44653.1 - 0.44 11.0 5.0 25 5.4 0.2 4.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Auts2 PF15336.6 OWF44653.1 - 0.98 9.5 3.9 5.9 7.0 0.2 2.4 1 1 1 2 2 2 0 Autism susceptibility gene 2 protein Filamin PF00630.19 OWF44654.1 - 2.6e-75 249.8 7.0 2.4e-13 50.8 0.0 8.3 8 0 0 8 8 8 8 Filamin/ABP280 repeat CH PF00307.31 OWF44654.1 - 1.8e-47 160.0 0.2 3.6e-20 72.2 0.1 3.4 3 0 0 3 3 3 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OWF44654.1 - 1.1e-07 31.5 0.0 0.12 12.2 0.0 3.5 3 0 0 3 3 3 3 CAMSAP CH domain Y_Y_Y PF07495.13 OWF44654.1 - 0.0008 19.3 0.6 13 5.8 0.1 5.1 5 0 0 5 5 5 1 Y_Y_Y domain Big_3_5 PF16640.5 OWF44654.1 - 0.0011 19.1 5.2 1.7 8.9 1.9 4.6 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 3) DUF5060 PF16586.5 OWF44654.1 - 0.14 12.6 0.3 1.1e+02 3.3 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5060) YbbR PF07949.12 OWF44654.1 - 4.1 7.8 7.5 41 4.6 0.1 4.9 4 1 1 5 5 5 0 YbbR-like protein Trypsin_2 PF13365.6 OWF44655.1 - 1.4e-06 29.3 0.0 2.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF44655.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin F-box-like PF12937.7 OWF44656.1 - 3.6e-07 30.0 0.8 5.9e-07 29.3 0.2 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OWF44656.1 - 4e-07 29.7 0.4 8.7e-07 28.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OWF44656.1 - 0.0035 17.2 0.1 0.0057 16.5 0.1 1.3 1 0 0 1 1 1 1 F-box Sulfotransfer_2 PF03567.14 OWF44657.1 - 9.4e-55 186.3 6.7 1.2e-54 185.9 6.7 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF1640 PF07798.11 OWF44657.1 - 0.082 12.9 4.3 0.17 11.9 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Sulfotransfer_1 PF00685.27 OWF44659.1 - 6.2e-27 94.7 2.5 1.2e-26 93.8 2.5 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF44659.1 - 0.086 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family IgGFc_binding PF17517.2 OWF44660.1 - 9e-138 458.4 31.7 1.5e-70 237.8 7.1 3.0 3 0 0 3 3 3 2 IgGFc binding protein TSP_1 PF00090.19 OWF44660.1 - 7.8e-91 298.1 198.2 4.2e-11 42.9 9.1 13.5 13 0 0 13 13 13 12 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF44660.1 - 1.7e-09 37.7 31.3 2.5e-06 27.6 12.1 6.0 5 0 0 5 5 5 2 Low-density lipoprotein receptor domain class A IgGFc_binding PF17517.2 OWF44661.1 - 2e-69 234.1 7.5 2e-69 234.1 7.5 2.0 2 0 0 2 2 2 1 IgGFc binding protein TSP_1 PF00090.19 OWF44661.1 - 4.7e-65 215.6 147.6 1.9e-12 47.2 13.2 8.9 8 0 0 8 8 8 8 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF44661.1 - 2.4e-06 27.7 11.4 2.4e-06 27.7 11.4 5.5 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A Aldedh PF00171.22 OWF44662.1 - 1.1e-186 620.8 0.0 1.3e-186 620.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family KAR PF15222.6 OWF44662.1 - 0.052 13.8 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Kidney androgen-regulated DUF1487 PF07368.11 OWF44662.1 - 0.097 12.1 0.0 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DtxR PF18357.1 OWF44662.1 - 0.19 11.4 0.1 0.39 10.4 0.1 1.5 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain DUF745 PF05335.13 OWF44663.1 - 0.00026 20.8 7.8 0.00026 20.8 7.8 7.2 3 2 5 8 8 8 2 Protein of unknown function (DUF745) NPV_P10 PF05531.12 OWF44663.1 - 0.014 15.8 1.2 0.014 15.8 1.2 9.8 5 3 1 6 6 6 0 Nucleopolyhedrovirus P10 protein TMP_2 PF06791.13 OWF44663.1 - 0.51 10.0 12.5 0.26 10.9 0.2 4.1 4 1 0 4 4 4 0 Prophage tail length tape measure protein Glyco_transf_11 PF01531.16 OWF44664.1 - 0.031 13.5 2.0 0.053 12.7 0.8 2.0 1 1 0 2 2 2 0 Glycosyl transferase family 11 O-FucT PF10250.9 OWF44664.1 - 0.046 13.4 0.3 0.079 12.6 0.3 1.4 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase IBR PF01485.21 OWF44665.1 - 1.2e-18 67.1 24.7 6.3e-13 48.7 9.6 5.2 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OWF44665.1 - 0.00096 19.0 10.1 0.00096 19.0 10.1 5.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RCC1 PF00415.18 OWF44666.1 - 4.5e-56 187.3 13.9 5.6e-10 39.7 0.1 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF44666.1 - 3.5e-30 103.1 32.5 1.6e-07 30.9 1.6 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat zf-H2C2_5 PF13909.6 OWF44667.1 - 2.2e-15 56.1 70.7 3.4e-05 23.5 0.3 8.2 8 0 0 8 8 8 6 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF44667.1 - 8.5e-14 51.1 85.5 0.00082 19.7 5.3 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF44667.1 - 4.7e-11 42.6 63.8 0.00017 21.9 5.9 10.0 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF44667.1 - 0.0033 18.1 77.6 0.37 11.8 4.1 9.6 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_7 PF15269.6 OWF44667.1 - 0.04 14.0 43.7 0.23 11.6 0.1 7.2 3 2 3 6 6 6 0 Zinc-finger 14-3-3 PF00244.20 OWF44669.1 - 1e-94 316.2 6.9 1.2e-94 316.0 6.9 1.0 1 0 0 1 1 1 1 14-3-3 protein SIKE PF05769.11 OWF44669.1 - 0.03 14.2 2.5 0.32 10.9 1.1 2.4 2 0 0 2 2 2 0 SIKE family SF3A2 PF16835.5 OWF44669.1 - 0.11 12.9 0.3 0.34 11.3 0.1 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) RL10P_insert PF17777.1 OWF44670.1 - 1.1e-25 89.5 0.0 1.9e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OWF44670.1 - 3.1e-21 75.4 0.0 4.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 INT_SG_DDX_CT_C PF15300.6 OWF44670.1 - 0.057 13.2 0.3 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus ACOX PF01756.19 OWF44671.1 - 8.3e-60 201.4 0.3 1.6e-59 200.5 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OWF44671.1 - 2.7e-32 111.9 0.1 5.6e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OWF44671.1 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OWF44671.1 - 0.005 17.5 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OWF44671.1 - 0.026 14.7 0.0 0.13 12.4 0.0 2.2 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DCB PF16213.5 OWF44671.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3007 PF11460.8 OWF44671.1 - 1.5 9.1 3.8 6.7 7.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Ion_trans PF00520.31 OWF44672.1 - 3.2e-43 147.7 13.5 4.1e-43 147.4 13.5 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF44672.1 - 4.9e-29 100.5 0.0 1.3e-28 99.2 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF44672.1 - 3.9e-10 39.6 8.5 3.9e-10 39.6 8.5 2.1 2 1 0 2 2 2 1 Ion channel MARVEL PF01284.23 OWF44672.1 - 2.3 8.2 8.9 1.7 8.7 3.5 2.7 2 1 0 2 2 2 0 Membrane-associating domain Arabinose_trans PF04602.12 OWF44674.1 - 0.0082 15.0 88.9 1.2 7.9 4.7 12.3 1 1 19 20 20 20 20 Mycobacterial cell wall arabinan synthesis protein cEGF PF12662.7 OWF44674.1 - 0.024 14.6 0.3 35 4.5 0.0 6.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like Amino_oxidase PF01593.24 OWF44675.1 - 1.9e-65 221.9 0.0 4.1e-64 217.6 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF44675.1 - 4.2e-08 33.3 0.0 8.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF44675.1 - 1.5e-06 28.1 0.0 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF44675.1 - 3.3e-06 26.5 0.5 0.00014 21.2 0.0 2.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OWF44675.1 - 7.7e-06 25.3 0.3 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF44675.1 - 0.00068 19.7 0.2 0.014 15.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OWF44675.1 - 0.013 14.8 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF44675.1 - 0.035 12.8 0.9 1.2 7.7 0.0 3.2 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 OWF44675.1 - 0.041 14.4 0.1 0.46 11.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OWF44675.1 - 0.043 13.1 0.2 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OWF44675.1 - 0.045 12.8 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 OWF44675.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CAP-ZIP_m PF15255.6 OWF44676.1 - 4.5e-20 72.4 8.4 1.5e-12 48.0 2.4 3.5 1 1 1 2 2 2 2 WASH complex subunit CAP-Z interacting, central region ULD PF16534.5 OWF44677.1 - 8.5e-36 122.3 0.0 1.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB CUTL PF16557.5 OWF44677.1 - 2.4e-26 91.7 0.3 2.4e-26 91.7 0.3 2.2 2 0 0 2 2 2 1 CUT1-like DNA-binding domain of SATB Homeodomain PF00046.29 OWF44677.1 - 4.2e-05 23.3 4.0 4.2e-05 23.3 4.0 2.4 3 0 0 3 3 3 1 Homeodomain YdaS_antitoxin PF15943.5 OWF44677.1 - 0.004 17.0 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_20 PF12840.7 OWF44677.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SspO PF08175.12 OWF44677.1 - 0.18 12.3 2.1 0.78 10.3 0.5 2.5 2 0 0 2 2 2 0 Small acid-soluble spore protein O family EMP70 PF02990.16 OWF44678.1 - 3.6e-158 527.5 14.2 5.2e-158 527.0 14.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PTPLA PF04387.14 OWF44679.1 - 9.5e-61 204.3 11.1 9.5e-61 204.3 11.1 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Caps_assemb_Wzi PF14052.6 OWF44680.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Capsule assembly protein Wzi PLAT PF01477.23 OWF44681.1 - 1.8e-18 67.2 1.2 1e-07 32.5 0.1 2.8 2 0 0 2 2 2 2 PLAT/LH2 domain LRR_6 PF13516.6 OWF44681.1 - 2e-11 43.0 20.8 0.00066 19.5 0.1 6.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 OWF44681.1 - 0.029 14.8 0.3 0.029 14.8 0.3 3.4 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) ArfGap PF01412.18 OWF44682.1 - 1.2e-33 115.6 0.1 5.6e-33 113.5 0.0 2.2 2 0 0 2 2 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 OWF44682.1 - 1e-26 94.2 12.7 2.1e-26 93.1 12.7 1.5 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 OWF44682.1 - 4.7e-15 55.9 6.2 1.2e-08 35.4 0.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SH3_9 PF14604.6 OWF44682.1 - 5.5e-15 54.9 0.2 1.3e-14 53.8 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF44682.1 - 1.1e-14 53.7 0.2 2.6e-14 52.6 0.2 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 OWF44682.1 - 8.9e-14 51.9 1.6 1.3e-13 51.4 0.2 2.0 2 0 0 2 2 1 1 PH domain SH3_2 PF07653.17 OWF44682.1 - 2.3e-13 49.6 0.0 6e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 OWF44682.1 - 2.2e-10 40.6 0.1 2.1e-08 34.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF44682.1 - 5.3e-09 36.1 0.0 0.024 15.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OWF44682.1 - 9.7e-05 22.8 0.1 0.14 12.8 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44682.1 - 0.00042 20.5 0.0 1.5 9.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat PH_9 PF15410.6 OWF44682.1 - 0.0038 17.6 1.8 0.016 15.6 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Tektin PF03148.14 OWF44682.1 - 0.013 14.3 5.7 1.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Tektin family BST2 PF16716.5 OWF44682.1 - 0.034 14.7 3.6 0.46 11.1 0.1 3.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4404 PF14357.6 OWF44682.1 - 0.29 11.8 3.3 13 6.5 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 OWF44682.1 - 0.33 11.0 2.4 2.1 8.4 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2408 PF10303.9 OWF44682.1 - 9.7 6.8 11.0 3 8.4 0.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Orthoreo_P10 PF07204.11 OWF44683.1 - 8.8e-13 48.0 103.3 35 4.4 0.3 25.9 1 1 55 56 56 56 55 Orthoreovirus membrane fusion protein p10 PagL PF09411.10 OWF44683.1 - 3.2e-06 27.3 0.5 30 4.8 0.3 11.3 1 1 1 2 2 2 1 Lipid A 3-O-deacylase (PagL) Pkinase PF00069.25 OWF44684.1 - 6.8e-39 133.8 0.0 8.7e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF44684.1 - 5.5e-17 61.9 0.0 7.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF44684.1 - 0.0086 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like CAP_N PF01213.19 OWF44685.1 - 1.8e-104 349.7 0.1 1.8e-104 349.7 0.1 1.9 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OWF44685.1 - 4.7e-63 211.5 8.4 6.3e-63 211.1 8.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OWF44685.1 - 0.035 13.9 3.4 0.089 12.5 3.2 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor C Methyltransf_21 PF05050.12 OWF44686.1 - 6.4e-06 26.3 0.0 9.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain SCRG1 PF15224.6 OWF44686.1 - 0.16 12.1 0.1 0.77 9.9 0.0 2.1 1 1 1 2 2 2 0 Scrapie-responsive protein 1 RRM_1 PF00076.22 OWF44688.1 - 7e-19 67.4 0.0 1.1e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF44688.1 - 0.00069 19.7 0.1 0.0018 18.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif RRM_1 PF00076.22 OWF44689.1 - 3.9e-39 132.3 0.0 1e-23 83.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OWF44689.1 - 8e-26 91.0 0.1 1.6e-25 90.0 0.1 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OWF44689.1 - 7.8e-06 25.7 0.0 8.1e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OWF44689.1 - 0.0073 15.9 0.0 0.12 12.0 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OWF44689.1 - 0.052 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain BRAP2 PF07576.12 OWF44689.1 - 0.065 13.5 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_7 PF16367.5 OWF44689.1 - 0.12 12.5 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF1866 PF08952.11 OWF44689.1 - 0.14 12.0 0.0 5 7.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) MARVEL PF01284.23 OWF44690.1 - 1e-06 28.8 20.8 2.1e-06 27.8 20.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain LapA_dom PF06305.11 OWF44690.1 - 0.033 14.0 0.7 0.033 14.0 0.7 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pex24p PF06398.11 OWF44690.1 - 0.15 11.1 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin IRS PF02174.17 OWF44691.1 - 4.7e-14 52.1 0.0 9.6e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 OWF44691.1 - 0.018 15.5 0.6 0.1 13.1 0.6 2.5 1 1 0 1 1 1 0 PH domain EF_TS PF00889.19 OWF44691.1 - 0.088 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Elongation factor TS Ras PF00071.22 OWF44692.1 - 4e-56 189.1 0.0 5.2e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF44692.1 - 2.7e-36 124.4 0.0 4.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF44692.1 - 4.8e-14 52.2 0.0 5.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF44692.1 - 2.7e-05 24.2 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF44692.1 - 0.0001 21.9 0.0 0.0003 20.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF44692.1 - 0.00049 19.5 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OWF44692.1 - 0.0034 16.8 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OWF44692.1 - 0.021 15.2 0.1 0.031 14.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_34 PF13872.6 OWF44692.1 - 0.049 12.5 0.2 0.092 11.6 0.2 1.4 1 1 1 2 2 2 0 P-loop containing NTP hydrolase pore-1 YwhD PF08741.10 OWF44692.1 - 0.067 12.9 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 YwhD family TniB PF05621.11 OWF44692.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 OWF44692.1 - 0.077 12.9 0.1 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 OWF44692.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase G-alpha PF00503.20 OWF44692.1 - 0.1 11.7 0.4 1.8 7.7 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit Cys_rich_VLP PF14194.6 OWF44693.1 - 0.76 9.9 14.8 2.3 8.4 3.6 2.5 1 1 0 2 2 2 0 Cysteine-rich VLP LytR_cpsA_psr PF03816.14 OWF44693.1 - 1.5 9.0 4.3 14 5.8 1.3 2.6 1 1 2 3 3 3 0 Cell envelope-related transcriptional attenuator domain T-box PF00907.22 OWF44695.1 - 5.4e-78 261.5 0.1 7.4e-78 261.0 0.1 1.2 1 0 0 1 1 1 1 T-box PHD PF00628.29 OWF44696.1 - 0.04 13.8 5.8 0.073 13.0 5.8 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_C48 PF02902.19 OWF44697.1 - 0.0005 20.0 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Epimerase PF01370.21 OWF44698.1 - 2.2e-54 184.5 0.0 3e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF44698.1 - 3.6e-14 52.9 0.6 2.6e-13 50.1 0.6 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OWF44698.1 - 1.5e-05 24.2 0.0 3.5e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OWF44698.1 - 0.00054 19.2 2.0 0.0035 16.5 0.0 2.5 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OWF44698.1 - 0.00091 18.3 0.3 0.0032 16.5 0.3 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OWF44698.1 - 0.0022 17.2 0.1 0.01 15.0 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein UEV PF05743.13 OWF44698.1 - 0.1 12.4 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 UEV domain BIR PF00653.21 OWF44699.1 - 1.2e-23 83.6 13.2 6.2e-12 46.0 2.6 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-Di19 PF05605.12 OWF44699.1 - 0.0011 19.3 4.2 0.64 10.4 0.4 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Fer4_9 PF13187.6 OWF44699.1 - 0.85 9.8 4.0 5.7 7.2 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 OWF44699.1 - 1.6 9.4 11.0 3.1 8.5 1.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain BIR PF00653.21 OWF44700.1 - 3.9e-10 40.2 0.6 8.8e-10 39.1 0.6 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain ArAE_2_N PF10337.9 OWF44700.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal LRR_6 PF13516.6 OWF44701.1 - 2e-14 52.3 26.7 0.012 15.6 0.6 9.2 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 OWF44701.1 - 0.00091 19.5 3.7 5.1 8.0 0.2 6.1 8 0 0 8 8 8 1 Leucine Rich Repeat UPF0175 PF03683.13 OWF44701.1 - 0.082 12.6 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) LRR_4 PF12799.7 OWF44701.1 - 2.9 8.5 21.2 0.24 11.9 0.5 4.6 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) BIR PF00653.21 OWF44702.1 - 1.1e-50 170.2 9.9 8e-21 74.5 0.4 4.1 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain Fam20C PF06702.12 OWF44704.1 - 0.00082 19.3 3.0 0.0062 16.4 0.3 2.8 3 1 0 3 3 3 1 Golgi casein kinase, C-terminal, Fam20 7tm_1 PF00001.21 OWF44705.1 - 3.2e-47 161.1 23.5 5e-47 160.4 23.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF44705.1 - 3e-07 30.1 20.9 4.9e-07 29.4 20.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF44705.1 - 1.9e-06 27.8 17.2 6.1e-06 26.2 17.2 1.8 1 1 0 1 1 1 1 Olfactory receptor UL45 PF05473.12 OWF44706.1 - 0.00035 20.3 0.1 0.00053 19.7 0.1 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF44706.1 - 0.0013 19.4 0.0 0.0022 18.7 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 OWF44706.1 - 0.086 12.1 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein SASA PF03629.18 OWF44707.1 - 7.7e-16 58.4 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DUF4982 PF16355.5 OWF44707.1 - 0.14 12.1 0.0 0.46 10.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) SASA PF03629.18 OWF44708.1 - 5.7e-13 49.0 0.0 1.3e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 OWF44709.1 - 1.3e-15 57.7 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase 7tm_1 PF00001.21 OWF44710.1 - 0.00039 19.8 24.5 0.0005 19.5 24.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44710.1 - 0.11 12.1 24.0 0.057 13.0 22.1 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PBP1_TM PF14812.6 OWF44711.1 - 0.056 13.8 0.9 0.069 13.5 0.9 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sugar_tr PF00083.24 OWF44712.1 - 2.1e-33 115.9 22.5 3.5e-33 115.1 22.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF44712.1 - 8.5e-29 100.6 55.6 8.7e-22 77.5 34.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NCE101 PF11654.8 OWF44712.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 PSI_PSAK PF01241.18 OWF44712.1 - 0.15 12.1 2.3 0.68 10.0 1.7 2.5 2 1 0 2 2 2 0 Photosystem I psaG / psaK TRI12 PF06609.13 OWF44712.1 - 0.63 8.4 11.7 0.17 10.3 1.6 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) SASA PF03629.18 OWF44713.1 - 1.7e-14 54.0 0.0 8.1e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Peptidase_M1 PF01433.20 OWF44714.1 - 6e-70 235.2 1.1 1e-69 234.4 1.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OWF44714.1 - 4.4e-63 213.7 0.3 9.2e-63 212.7 0.1 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OWF44714.1 - 7.3e-41 140.4 0.1 1.2e-40 139.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEPN_DZIP3 PF18738.1 OWF44715.1 - 1.5e-13 50.7 0.4 4.2e-12 46.0 0.4 2.4 1 1 0 1 1 1 1 DZIP3/ hRUL138-like HEPN VWA_2 PF13519.6 OWF44715.1 - 4.1e-08 33.8 0.2 3.7e-07 30.7 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain MIB_HERC2 PF06701.13 OWF44715.1 - 0.0021 18.3 3.2 0.0049 17.1 3.2 1.7 1 0 0 1 1 1 1 Mib_herc2 PBECR3 PF18812.1 OWF44715.1 - 0.015 15.3 1.1 0.95 9.4 0.0 3.1 3 0 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 EMI PF07546.13 OWF44715.1 - 0.032 15.0 0.3 0.21 12.4 0.2 2.3 2 0 0 2 2 2 0 EMI domain Serine_rich PF08824.10 OWF44715.1 - 0.12 12.4 2.8 0.33 10.9 2.8 1.7 1 1 0 1 1 1 0 Serine rich protein interaction domain PAP_central PF04928.17 OWF44715.1 - 0.16 10.9 1.2 0.29 10.1 1.2 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF3585 PF12130.8 OWF44716.1 - 2.8e-42 144.1 26.0 2.8e-42 144.1 26.0 2.7 2 0 0 2 2 1 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 OWF44716.1 - 3.2e-18 65.9 0.1 9.2e-18 64.4 0.1 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OWF44716.1 - 1e-06 28.5 0.0 3.6e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain Pyr_redox_2 PF07992.14 OWF44716.1 - 3.5e-05 23.2 0.9 8.3e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF44716.1 - 4.7e-05 22.6 0.1 8.5e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OWF44716.1 - 5.2e-05 22.6 0.1 5.2e-05 22.6 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 OWF44716.1 - 0.00013 21.3 0.0 0.00045 19.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF44716.1 - 0.00064 20.2 0.1 0.0039 17.7 0.1 2.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF44716.1 - 0.00072 18.4 0.0 0.00072 18.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein LIM PF00412.22 OWF44716.1 - 0.0014 18.8 6.6 0.0034 17.6 6.6 1.7 1 0 0 1 1 1 1 LIM domain Lycopene_cycl PF05834.12 OWF44716.1 - 0.0029 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OWF44716.1 - 0.0034 16.8 0.1 0.0034 16.8 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OWF44716.1 - 0.0079 15.8 0.1 0.023 14.3 0.1 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF44716.1 - 0.04 14.2 0.1 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OWF44716.1 - 0.041 14.3 0.0 0.18 12.2 0.0 2.1 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 OWF44716.1 - 0.044 12.9 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF44716.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PCI PF01399.27 OWF44717.1 - 1e-10 42.0 0.1 4.3e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain DUF2605 PF10792.9 OWF44717.1 - 0.0036 17.2 2.6 0.0077 16.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2605) RPN7 PF10602.9 OWF44717.1 - 0.023 14.4 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF2800 PF10926.8 OWF44717.1 - 0.094 12.0 0.2 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) DUF4298 PF14131.6 OWF44717.1 - 0.13 12.2 1.4 24 5.0 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) HMMR_N PF15905.5 OWF44717.1 - 0.22 11.0 4.5 0.093 12.2 2.0 1.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal NAAA-beta PF15508.6 OWF44718.1 - 1.1e-11 44.9 0.7 1.5e-10 41.2 0.6 2.5 1 1 1 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.18 OWF44718.1 - 1.4e-09 38.1 0.6 5.8e-09 36.0 0.1 1.9 1 1 1 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Transposase_mut PF00872.18 OWF44718.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.4 2 0 0 2 2 2 0 Transposase, Mutator family adh_short PF00106.25 OWF44719.1 - 1.2e-24 86.9 0.5 7.2e-19 68.0 0.4 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF44719.1 - 3.9e-15 56.1 0.1 1.3e-12 47.8 0.1 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF44719.1 - 2.2e-07 31.0 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF44719.1 - 0.018 14.5 0.2 0.2 11.1 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3335 PF11814.8 OWF44719.1 - 0.085 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family GHMP_kinases_C PF08544.13 OWF44719.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 GHMP kinases C terminal Kelch_1 PF01344.25 OWF44721.1 - 3.4e-23 80.9 2.3 7.8e-08 31.8 0.0 5.8 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 OWF44721.1 - 7.2e-22 76.9 2.8 2e-05 24.7 0.0 5.6 3 1 3 6 6 6 4 Kelch motif Kelch_4 PF13418.6 OWF44721.1 - 2.2e-12 46.8 0.1 0.0042 17.0 0.0 4.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF44721.1 - 4.4e-11 42.8 0.0 0.051 13.9 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF44721.1 - 5e-10 39.1 10.5 0.0087 16.0 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 OWF44721.1 - 1.7e-09 37.3 4.1 0.0045 16.9 0.0 5.5 5 1 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 OWF44721.1 - 0.00062 20.2 0.5 0.0064 16.9 0.0 2.6 2 0 0 2 2 2 1 PQQ-like domain PQQ_2 PF13360.6 OWF44721.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain RicinB_lectin_2 PF14200.6 OWF44722.1 - 0.0035 18.0 0.0 0.14 12.9 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Macro PF01661.21 OWF44723.1 - 5.1e-09 36.2 0.0 8.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Macro domain adh_short PF00106.25 OWF44724.1 - 5.5e-20 71.6 0.0 8.7e-19 67.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF44724.1 - 2.2e-12 47.0 0.0 7.5e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF44724.1 - 2.4e-07 30.9 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Ig_J_chain PF15097.6 OWF44724.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin J chain Sulfotransfer_2 PF03567.14 OWF44725.1 - 6.6e-31 108.1 4.6 1e-30 107.5 4.6 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF2572 PF10833.8 OWF44725.1 - 0.13 12.0 2.9 0.069 12.9 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) CRPA PF05745.11 OWF44725.1 - 0.4 10.7 1.7 0.41 10.6 0.4 1.6 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Sulfotransfer_1 PF00685.27 OWF44726.1 - 3.9e-10 39.7 0.1 0.00049 19.7 0.0 2.0 1 1 1 2 2 2 2 Sulfotransferase domain BIR PF00653.21 OWF44727.1 - 2.1e-10 41.1 0.2 2.1e-10 41.1 0.2 2.9 2 1 1 3 3 3 1 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF44727.1 - 6.3e-07 29.2 8.4 6.3e-07 29.2 8.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44727.1 - 0.11 12.3 8.1 0.36 10.7 8.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C6H2 PF15801.5 OWF44727.1 - 5.7 7.3 8.9 5 7.5 0.0 3.6 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding BIR PF00653.21 OWF44728.1 - 2.4e-26 92.2 7.2 5.7e-14 52.5 0.2 3.7 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF44728.1 - 1.3e-05 25.0 8.7 3.6e-05 23.5 8.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44728.1 - 0.0073 16.2 8.2 0.0073 16.2 8.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OWF44728.1 - 0.049 13.5 8.3 0.19 11.6 8.3 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF44728.1 - 0.15 12.1 6.7 0.16 12.0 4.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger ArfGap PF01412.18 OWF44728.1 - 0.37 10.9 4.5 1.6 8.8 4.5 2.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-C3HC4_4 PF15227.6 OWF44728.1 - 0.54 10.5 8.8 2.3 8.4 5.8 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF44728.1 - 0.75 9.8 11.5 1.2 9.1 9.0 2.8 2 1 0 2 2 2 0 zinc-RING finger domain DUF2039 PF10217.9 OWF44728.1 - 1.5 9.2 10.3 0.2 12.0 4.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Zn_Tnp_IS1595 PF12760.7 OWF44728.1 - 6.4 6.8 8.1 21 5.2 6.3 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3795 PF12675.7 OWF44728.1 - 8.4 6.9 12.0 0.53 10.7 3.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) HIGH_NTase1 PF05636.11 OWF44729.1 - 0.059 12.6 0.3 0.062 12.5 0.3 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase BIR PF00653.21 OWF44730.1 - 1.3e-40 137.8 11.0 3.4e-20 72.4 0.9 3.7 3 1 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF44730.1 - 0.00012 21.9 1.9 0.00012 21.9 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) WIYLD PF10440.9 OWF44730.1 - 0.0019 17.9 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-binding WIYLD domain Prok-RING_4 PF14447.6 OWF44730.1 - 0.72 9.8 6.0 0.14 12.1 1.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PyrI_C PF02748.15 OWF44730.1 - 1.9 8.5 6.3 10 6.1 0.2 2.8 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain BIR PF00653.21 OWF44731.1 - 1.9e-67 223.9 23.4 3.6e-21 75.6 0.7 4.8 5 0 0 5 5 5 4 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 OWF44731.1 - 1.8e-06 28.1 5.7 0.31 11.1 0.0 4.5 4 2 0 4 4 4 3 C3HC zinc finger-like ATE_N PF04376.13 OWF44731.1 - 0.18 12.3 0.7 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus BIR PF00653.21 OWF44733.1 - 1.9e-05 25.2 6.8 0.00059 20.4 0.9 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain CYYR1 PF10873.8 OWF44734.1 - 0.038 14.4 2.3 0.054 13.9 2.3 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Ank_2 PF12796.7 OWF44735.1 - 1.1e-24 86.8 0.9 2.1e-15 57.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF44735.1 - 5.8e-16 58.1 0.1 0.004 17.6 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OWF44735.1 - 4.2e-15 54.4 1.6 0.0051 17.2 0.0 4.9 4 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF44735.1 - 7.7e-14 51.6 4.5 8.3e-07 29.2 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF44735.1 - 4.6e-13 49.4 1.8 0.0083 16.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Prok_Ub PF14454.6 OWF44735.1 - 1.8e-05 24.3 1.5 6.6 6.5 0.0 4.2 1 1 3 4 4 4 1 Prokaryotic Ubiquitin Chlam_vir PF05475.11 OWF44735.1 - 0.00011 21.9 0.3 15 5.3 0.0 3.8 1 1 3 4 4 4 0 Pgp3 C-terminal domain DUF429 PF04250.13 OWF44735.1 - 0.0024 17.7 0.0 1.6 8.5 0.0 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF429) Melibiase_2 PF16499.5 OWF44735.1 - 0.011 15.0 4.1 0.013 14.7 0.9 2.2 1 1 1 2 2 2 0 Alpha galactosidase A DUF4744 PF15918.5 OWF44735.1 - 0.024 15.5 0.4 2.8 8.9 0.4 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) TP_methylase PF00590.20 OWF44735.1 - 0.2 11.5 0.0 6.9 6.5 0.0 2.2 1 1 1 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Argos PF11581.8 OWF44735.1 - 0.42 10.6 7.5 16 5.5 0.1 3.4 1 1 3 4 4 4 0 Antagonist of EGFR signalling, Argos CDKN3 PF05706.12 OWF44735.1 - 0.47 10.1 3.6 0.63 9.7 2.8 1.7 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Sdh5 PF03937.16 OWF44735.1 - 0.88 9.6 3.3 27 4.8 0.1 2.8 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase 7tm_1 PF00001.21 OWF44736.1 - 1.2e-21 77.3 20.1 1.4e-21 77.1 20.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF44736.1 - 1.6e-06 27.9 29.1 2.5e-06 27.3 27.0 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF44736.1 - 0.00011 21.7 23.2 0.00014 21.4 23.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-CCHC PF00098.23 OWF44737.1 - 0.0092 16.0 0.3 0.02 15.0 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OWF44737.1 - 0.01 15.5 0.4 0.025 14.3 0.4 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 OWF44737.1 - 0.059 13.1 0.7 0.1 12.3 0.7 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-C2H2_4 PF13894.6 OWF44738.1 - 1.1e-14 53.9 41.4 0.56 11.2 0.6 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF44738.1 - 1.8e-11 44.0 28.6 0.76 10.1 0.3 8.8 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF44738.1 - 3.8e-10 39.8 32.5 0.23 11.9 0.0 9.0 8 0 0 8 8 8 6 Zinc-finger of C2H2 type C1_2 PF03107.16 OWF44738.1 - 4.1e-08 33.4 27.5 3.2 8.2 0.0 8.4 7 1 1 8 8 8 3 C1 domain DUF3449 PF11931.8 OWF44738.1 - 1.3e-05 25.1 34.7 2.8 7.7 0.5 8.1 8 0 0 8 8 8 5 Domain of unknown function (DUF3449) zf-C2H2_6 PF13912.6 OWF44738.1 - 0.00021 21.2 57.3 0.033 14.2 1.6 8.8 8 0 0 8 8 8 5 C2H2-type zinc finger Ephrin_rec_like PF07699.13 OWF44738.1 - 0.00052 19.7 19.0 21 5.0 0.1 7.8 8 0 0 8 8 8 0 Putative ephrin-receptor like zf-C2H2 PF00096.26 OWF44738.1 - 0.0026 18.1 45.8 7.6 7.2 0.9 8.6 8 0 0 8 8 8 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF44738.1 - 0.0065 16.8 36.8 7.3 7.2 0.2 8.7 8 0 0 8 8 8 1 Zinc-finger double domain PknG_rubred PF16919.5 OWF44738.1 - 0.0091 16.2 15.5 14 5.8 0.1 6.5 7 0 0 7 7 6 0 Protein kinase G rubredoxin domain zf-BED PF02892.15 OWF44738.1 - 0.046 13.8 20.8 25 5.0 0.2 7.2 7 0 0 7 7 7 0 BED zinc finger Inos-1-P_synth PF01658.17 OWF44738.1 - 0.096 12.9 13.0 6.3 7.1 1.0 5.0 3 2 2 5 5 5 0 Myo-inositol-1-phosphate synthase zf-nanos PF05741.13 OWF44738.1 - 0.18 12.1 30.8 4.7 7.5 0.2 8.4 8 0 0 8 8 8 0 Nanos RNA binding domain zf-Mss51 PF13824.6 OWF44738.1 - 1.2 9.3 31.5 12 6.1 0.1 8.0 3 3 4 8 8 8 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RRN7 PF11781.8 OWF44738.1 - 4.6 7.0 28.5 4.5 7.0 0.1 7.9 8 0 0 8 8 8 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-Sec23_Sec24 PF04810.15 OWF44738.1 - 9.6 6.4 28.7 76 3.5 0.1 8.2 9 0 0 9 9 9 0 Sec23/Sec24 zinc finger Abhydrolase_1 PF00561.20 OWF44739.1 - 4.1e-36 124.9 0.0 5.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF44739.1 - 1.1e-12 47.7 0.0 5.9e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF44739.1 - 5.1e-11 43.6 1.4 7.2e-11 43.1 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OWF44739.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 OWF44739.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 OWF44739.1 - 0.021 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 OWF44739.1 - 0.023 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.21 OWF44739.1 - 0.031 13.8 0.0 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OWF44740.1 - 4.6e-33 114.9 0.0 9.4e-33 113.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF44740.1 - 3.3e-13 49.5 0.0 9.2e-13 48.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF44740.1 - 6.4e-12 46.5 1.0 8.6e-12 46.1 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OWF44740.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.12 OWF44740.1 - 0.034 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 OWF44740.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 OWF44740.1 - 0.11 12.0 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Gal-bind_lectin PF00337.22 OWF44741.1 - 8.2e-30 103.1 0.0 1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin CUB PF00431.20 OWF44742.1 - 1.2e-15 57.8 0.3 1e-08 35.5 0.5 2.2 2 0 0 2 2 2 2 CUB domain GspH PF12019.8 OWF44742.1 - 0.26 11.7 4.3 0.12 12.9 0.8 2.2 2 1 0 2 2 2 0 Type II transport protein GspH zf-C2H2 PF00096.26 OWF44743.1 - 2.3e-25 87.6 100.3 7.3e-06 26.2 2.9 10.8 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF44743.1 - 1.6e-20 72.0 90.7 9.3e-05 23.0 3.0 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF44743.1 - 3.6e-07 30.3 85.7 0.00062 20.1 1.0 11.6 11 1 0 11 11 11 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF44743.1 - 0.00021 20.9 86.3 0.017 14.8 3.4 9.3 9 1 0 9 9 9 6 C2H2-type zinc-finger domain CpXC PF14353.6 OWF44743.1 - 0.0072 16.4 1.6 0.0072 16.4 1.6 7.0 2 1 4 7 7 7 3 CpXC protein zf-C2H2_6 PF13912.6 OWF44743.1 - 0.016 15.2 0.9 0.016 15.2 0.9 9.0 11 0 0 11 11 11 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF44743.1 - 0.016 15.5 69.7 0.13 12.6 1.9 9.8 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_6 PF14599.6 OWF44743.1 - 0.38 10.8 0.1 0.38 10.8 0.1 7.0 6 1 1 7 7 7 0 Zinc-ribbon Vps36-NZF-N PF16988.5 OWF44743.1 - 2.7 7.4 6.7 2.4 7.6 1.9 3.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Mab-21 PF03281.14 OWF44744.1 - 1.2e-24 87.2 3.1 4.6e-24 85.2 3.4 1.7 2 0 0 2 2 2 1 Mab-21 protein PIF3 PF05006.12 OWF44744.1 - 2.3 8.3 7.1 1.2 9.2 0.1 3.2 3 1 0 3 3 3 0 Per os infectivity factor 3 Mab-21 PF03281.14 OWF44745.1 - 1.4e-24 87.0 2.9 2.1e-24 86.3 2.9 1.3 1 0 0 1 1 1 1 Mab-21 protein B12-binding_2 PF02607.17 OWF44746.1 - 0.0054 17.2 0.0 0.0081 16.6 0.0 1.4 1 1 0 1 1 1 1 B12 binding domain Methyltransf_23 PF13489.6 OWF44747.1 - 4.8e-16 59.0 0.0 1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44747.1 - 1.1e-15 58.2 0.0 3.3e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44747.1 - 4.2e-14 53.0 0.0 8.1e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF44747.1 - 1.4e-11 44.9 0.0 2.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44747.1 - 4.2e-05 23.0 0.0 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OWF44747.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain D5_N PF08706.11 OWF44747.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 D5 N terminal like Methyltransf_24 PF13578.6 OWF44747.1 - 0.042 14.9 0.0 0.12 13.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 OWF44747.1 - 0.11 11.9 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Alba PF01918.21 OWF44748.1 - 1.2e-13 50.7 0.2 1.9e-13 50.0 0.2 1.3 1 0 0 1 1 1 1 Alba Condensin2nSMC PF12422.8 OWF44748.1 - 0.097 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit ExoD PF06055.12 OWF44748.1 - 0.22 10.9 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD DUF3653 PF12375.8 OWF44749.1 - 0.066 13.3 77.1 95 3.2 0.6 24.3 8 3 8 16 16 16 0 Phage protein Glycos_transf_2 PF00535.26 OWF44750.1 - 3e-28 98.8 0.0 5.1e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF44750.1 - 2.4e-14 53.7 0.2 4e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 OWF44750.1 - 1.7e-09 37.9 0.0 2.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF44750.1 - 0.00012 21.6 0.1 0.00029 20.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF44750.1 - 0.081 12.4 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF5440 PF17509.2 OWF44750.1 - 0.14 11.8 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5440) ICAP-1_inte_bdg PF10480.9 OWF44751.1 - 6.3e-24 85.1 0.3 9.3e-24 84.5 0.3 1.3 1 1 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.23 OWF44751.1 - 1.2e-12 48.1 0.2 1.4e-12 47.8 0.2 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 OWF44751.1 - 0.16 12.1 1.3 0.61 10.2 0.7 2.1 1 1 1 2 2 2 0 Phosphotyrosine-binding domain TFIIS_M PF07500.14 OWF44752.1 - 2e-34 118.4 3.1 3.6e-34 117.6 0.4 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OWF44752.1 - 4.7e-18 64.8 5.4 7.9e-18 64.0 5.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OWF44752.1 - 7.4e-11 41.9 3.2 7.4e-11 41.9 3.2 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-RRPl_C4 PF17026.5 OWF44752.1 - 0.036 14.2 1.1 0.082 13.0 1.1 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type LEDGF PF11467.8 OWF44752.1 - 0.056 13.1 0.8 0.11 12.1 0.8 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) LRR_6 PF13516.6 OWF44753.1 - 5.3e-27 91.5 17.2 0.0011 18.9 0.0 9.0 9 0 0 9 9 9 7 Leucine Rich repeat LRR_1 PF00560.33 OWF44753.1 - 9.1e-09 34.7 0.1 7.2 7.6 0.0 7.1 8 0 0 8 8 7 2 Leucine Rich Repeat EF-hand_1 PF00036.32 OWF44753.1 - 9.2e-08 31.1 7.0 0.00016 20.9 0.4 3.3 3 0 0 3 3 3 2 EF hand LRR_4 PF12799.7 OWF44753.1 - 3.3e-07 30.5 6.0 0.0034 17.8 0.1 4.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.6 OWF44753.1 - 2.5e-05 23.8 5.1 0.0014 18.4 0.5 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 OWF44753.1 - 0.0003 20.6 8.8 0.043 13.7 0.7 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF44753.1 - 0.00037 19.9 8.1 0.12 11.9 0.9 3.0 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 OWF44753.1 - 0.00055 20.8 0.1 0.0015 19.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OWF44753.1 - 0.00057 20.3 12.4 0.0022 18.4 5.8 3.3 3 1 1 4 4 4 2 EF-hand domain pair LRR_8 PF13855.6 OWF44753.1 - 0.001 18.8 9.7 1 9.2 0.1 5.6 4 2 1 5 5 5 2 Leucine rich repeat EF-hand_4 PF12763.7 OWF44753.1 - 0.019 14.9 2.5 0.059 13.3 2.4 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand AA_permease_2 PF13520.6 OWF44754.1 - 4.4e-51 174.0 44.1 5.5e-51 173.7 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF44754.1 - 2e-29 102.5 43.6 4e-29 101.5 43.6 1.4 1 1 0 1 1 1 1 Amino acid permease Ndc1_Nup PF09531.10 OWF44754.1 - 3.1 6.4 8.2 7.2 5.2 8.2 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AA_permease_2 PF13520.6 OWF44755.1 - 1.9e-34 119.2 25.4 6.4e-23 81.3 12.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 OWF44755.1 - 6.3e-16 58.0 25.5 1.5e-10 40.3 12.3 2.0 1 1 1 2 2 2 2 Amino acid permease Ank_2 PF12796.7 OWF44756.1 - 8.9e-73 240.9 17.7 5.1e-14 52.6 0.1 8.3 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF44756.1 - 1.1e-66 220.4 17.5 7.2e-11 42.4 0.3 10.8 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 OWF44756.1 - 6.3e-54 178.2 29.8 8.5e-07 29.2 0.0 14.8 15 0 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.6 OWF44756.1 - 8.5e-52 172.5 14.3 2.6e-07 30.8 0.0 12.3 7 4 5 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44756.1 - 2.5e-51 165.6 16.4 0.00028 21.1 0.0 15.0 15 0 0 15 15 15 12 Ankyrin repeat Ion_trans PF00520.31 OWF44756.1 - 3.5e-07 29.7 24.6 4e-07 29.5 23.7 1.5 2 0 0 2 2 2 1 Ion transport protein C12orf66_like PF09404.10 OWF44756.1 - 0.037 12.9 0.3 0.063 12.1 0.3 1.3 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like LURAP PF14854.6 OWF44757.1 - 1.7e-06 27.9 2.5 2e-06 27.7 2.0 1.4 1 1 0 1 1 1 1 Leucine rich adaptor protein DUF3584 PF12128.8 OWF44757.1 - 0.019 12.5 0.1 0.02 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM167 PF11652.8 OWF44757.1 - 0.035 14.6 0.2 0.094 13.2 0.2 1.8 1 0 0 1 1 1 0 FAM167 Lig_chan-Glu_bd PF10613.9 OWF44758.1 - 7.9e-20 71.2 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF44758.1 - 3.5e-18 65.9 0.0 8.3e-18 64.6 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 OWF44758.1 - 1.1e-15 57.8 0.1 2.8e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 OWF44758.1 - 7e-08 32.0 0.0 3.1e-07 29.8 0.0 1.8 1 1 1 2 2 2 1 Receptor family ligand binding region Alba PF01918.21 OWF44758.1 - 0.051 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Alba Glyco_hydro_68 PF02435.16 OWF44758.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Levansucrase/Invertase DUF190 PF02641.15 OWF44758.1 - 0.064 13.6 0.2 18 5.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized ACR, COG1993 Endonuc-BsobI PF09194.10 OWF44759.1 - 0.0023 17.2 0.7 15 4.7 0.0 4.1 1 1 3 4 4 4 3 Restriction endonuclease BsobI DUF577 PF04510.12 OWF44759.1 - 0.012 15.5 3.3 45 3.9 0.1 4.6 1 1 4 5 5 5 0 Family of unknown function (DUF577) HSBP1 PF06825.12 OWF44760.1 - 0.49 10.3 4.5 7 6.6 0.2 3.1 2 1 1 3 3 3 0 Heat shock factor binding protein 1 Pim PF16765.5 OWF44761.1 - 1.4e-08 34.8 0.7 1.4 9.1 0.0 5.0 1 1 6 7 7 7 6 Pesticin immunity protein DUF3739 PF12545.8 OWF44761.1 - 2.3e-06 28.0 0.1 3.7 8.1 0.0 4.1 1 1 3 4 4 4 4 Filamentous haemagglutinin family outer membrane protein RicinB_lectin_2 PF14200.6 OWF44761.1 - 0.00038 21.1 3.7 2.1 9.1 3.7 5.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like HATPase_c_3 PF13589.6 OWF44761.1 - 0.0012 18.6 6.4 10 5.9 0.6 5.7 1 1 3 4 4 4 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GH97_N PF14508.6 OWF44761.1 - 0.0041 16.6 12.6 19 4.7 0.4 5.3 1 1 1 2 2 2 1 Glycosyl-hydrolase 97 N-terminal NdhM PF10664.9 OWF44761.1 - 0.46 10.8 4.5 11 6.4 0.2 3.1 1 1 2 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M Pim PF16765.5 OWF44762.1 - 2.8e-14 53.1 8.4 0.59 10.3 0.0 8.6 1 1 9 10 10 10 6 Pesticin immunity protein DUF3739 PF12545.8 OWF44762.1 - 1.8e-13 50.9 0.5 2.6 8.5 0.0 7.3 2 2 5 7 7 7 5 Filamentous haemagglutinin family outer membrane protein HATPase_c_3 PF13589.6 OWF44762.1 - 0.025 14.4 21.3 6.8 6.5 0.0 9.0 2 2 6 8 8 8 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Polyketide_cyc2 PF10604.9 OWF44762.1 - 0.59 10.4 13.6 7.9 6.7 0.1 4.7 1 1 2 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport NdhM PF10664.9 OWF44762.1 - 3.2 8.1 17.8 17 5.8 1.6 5.4 1 1 5 6 6 6 0 Cyanobacterial and plastid NDH-1 subunit M Pim PF16765.5 OWF44763.1 - 0.00014 21.9 0.5 0.11 12.6 0.1 3.0 1 1 3 4 4 4 4 Pesticin immunity protein DUF3739 PF12545.8 OWF44763.1 - 0.0047 17.4 0.1 3 8.4 0.0 2.7 1 1 2 3 3 3 3 Filamentous haemagglutinin family outer membrane protein GH97_N PF14508.6 OWF44763.1 - 0.0063 16.0 5.0 19 4.7 5.0 3.5 1 1 0 1 1 1 1 Glycosyl-hydrolase 97 N-terminal DUF1386 PF07138.11 OWF44763.1 - 4.2 6.5 6.8 7.8 5.7 0.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1386) Pim PF16765.5 OWF44764.1 - 2e-10 40.7 1.1 0.47 10.6 0.0 5.1 1 1 5 6 6 6 5 Pesticin immunity protein DUF3739 PF12545.8 OWF44764.1 - 1.5e-06 28.6 0.4 2.5 8.6 0.0 4.1 1 1 3 4 4 4 4 Filamentous haemagglutinin family outer membrane protein RicinB_lectin_2 PF14200.6 OWF44764.1 - 8.5e-05 23.2 5.4 2.8 8.7 5.4 5.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Big_3_2 PF12245.8 OWF44764.1 - 0.00097 19.4 0.2 12 6.1 0.0 3.8 1 1 3 4 4 4 1 Bacterial Ig-like domain HATPase_c_3 PF13589.6 OWF44764.1 - 0.0029 17.4 9.9 6.7 6.5 0.1 5.8 1 1 3 4 4 4 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NdhM PF10664.9 OWF44764.1 - 0.065 13.5 3.4 18 5.6 0.1 3.1 1 1 2 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M GH97_N PF14508.6 OWF44764.1 - 0.29 10.6 8.5 8.9 5.7 0.7 4.7 1 1 1 2 2 2 0 Glycosyl-hydrolase 97 N-terminal Lig_chan-Glu_bd PF10613.9 OWF44765.1 - 3.4e-25 88.5 0.1 8e-24 84.1 0.0 2.6 1 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF44765.1 - 8.7e-21 74.4 0.0 1.6e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 OWF44765.1 - 4e-20 72.2 0.0 7.5e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 OWF44765.1 - 3.8e-17 62.4 0.5 8.2e-15 54.8 0.5 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region HDV_ag PF01517.18 OWF44765.1 - 0.19 11.5 0.4 0.34 10.7 0.4 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen ASC PF00858.24 OWF44766.1 - 1.7e-90 304.2 4.4 2.1e-90 303.8 4.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Herpes_UL73 PF03554.13 OWF44766.1 - 0.081 12.9 1.0 0.22 11.6 1.0 1.7 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein YWFCY PF14293.6 OWF44766.1 - 0.099 13.0 0.3 0.28 11.5 0.3 1.8 1 0 0 1 1 1 0 YWFCY protein ASC PF00858.24 OWF44767.1 - 5.3e-68 230.0 12.4 5.6e-38 131.1 9.6 2.2 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel ASC PF00858.24 OWF44768.1 - 7.5e-89 298.7 6.3 9.4e-89 298.4 6.3 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF3073 PF11273.8 OWF44768.1 - 3.1 8.6 7.0 0.39 11.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) Glyco_hydro_20 PF00728.22 OWF44769.1 - 1.1e-13 51.3 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 OWF44769.1 - 3.7e-06 26.5 0.9 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4838) SUI1 PF01253.22 OWF44770.1 - 3e-20 72.5 0.1 6.6e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.18 OWF44770.1 - 6.8e-07 29.1 0.0 2.1e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain Pre-PUA PF17832.1 OWF44770.1 - 3.5e-06 27.6 1.3 6e-06 26.9 0.2 2.1 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 OWF44770.1 - 0.00013 21.9 0.0 0.00033 20.6 0.0 1.7 2 0 0 2 2 2 1 PUA domain Glyco_transf_10 PF00852.19 OWF44771.1 - 1.5e-41 142.1 3.8 2.6e-41 141.3 3.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF44771.1 - 2.8e-17 63.2 0.1 2.8e-17 63.2 0.1 2.5 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal Acyltransferase PF01553.21 OWF44773.1 - 2.3e-07 30.5 0.0 4.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 OWF44773.1 - 0.0023 16.9 0.0 0.0044 16.0 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Octopine_DH PF02317.17 OWF44774.1 - 2.1e-30 105.8 0.0 3.3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 OWF44774.1 - 6e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OWF44774.1 - 0.0035 17.9 0.0 0.0076 16.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OWF44774.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 OWF44774.1 - 0.19 11.3 0.4 1.2 8.7 0.0 2.0 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SDF PF00375.18 OWF44775.1 - 1.1e-92 311.1 34.2 1.3e-92 310.9 34.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5389 PF17364.2 OWF44775.1 - 2.5 8.2 7.2 0.13 12.3 0.8 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5389) SDF PF00375.18 OWF44776.1 - 6.4e-15 55.1 2.4 6.8e-15 55.0 2.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 OWF44777.1 - 2.9e-35 122.1 20.1 9.2e-19 67.7 8.3 3.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family DUF5325 PF17259.2 OWF44777.1 - 0.83 9.6 3.8 2.9 7.9 3.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Metallophos PF00149.28 OWF44778.1 - 3.7e-17 63.5 0.6 5.1e-17 63.1 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Neur_chan_memb PF02932.16 OWF44779.1 - 1.6e-12 48.0 2.1 2.1e-12 47.6 2.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF5336 PF17270.2 OWF44779.1 - 0.69 9.5 3.6 0.36 10.5 1.5 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Neur_chan_LBD PF02931.23 OWF44780.1 - 2.4e-18 66.4 0.3 3.1e-18 66.0 0.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Carm_PH PF17888.1 OWF44780.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Carmil pleckstrin homology domain Reeler PF02014.16 OWF44781.1 - 2.9e-19 70.1 0.1 4.1e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Reeler domain Reeler PF02014.16 OWF44782.1 - 2.3e-21 76.9 0.0 3.7e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Reeler domain s48_45 PF07422.13 OWF44782.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 1 0 1 1 1 0 Sexual stage antigen s48/45 domain SDF PF00375.18 OWF44783.1 - 4.7e-129 430.8 23.2 5.6e-129 430.6 23.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family NiFe_hyd_3_EhaA PF17367.2 OWF44783.1 - 1.2 9.3 9.2 4.5 7.5 0.5 3.2 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A Ribosomal_S21e PF01249.18 OWF44784.1 - 1.3e-42 143.8 0.3 1.4e-42 143.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e WD40 PF00400.32 OWF44785.1 - 6.8e-14 52.1 7.7 0.00081 20.2 0.1 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF44785.1 - 1.3e-11 44.6 1.5 0.0005 20.3 0.1 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Condensin2nSMC PF12422.8 OWF44786.1 - 2.5e-08 34.2 12.9 0.083 13.1 0.2 5.4 1 1 5 6 6 6 5 Condensin II non structural maintenance of chromosomes subunit Rubrerythrin PF02915.17 OWF44786.1 - 6.7e-06 26.5 6.3 1.5 9.2 0.3 4.1 1 1 4 5 5 5 2 Rubrerythrin Apolipoprotein PF01442.18 OWF44786.1 - 1.9e-05 24.6 0.0 6.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF697 PF05128.12 OWF44786.1 - 2e-05 24.3 0.7 4.9 6.9 0.0 4.4 2 1 2 5 5 5 1 Domain of unknown function (DUF697) Serine_rich PF08824.10 OWF44786.1 - 8.7e-05 22.6 6.9 0.52 10.3 0.4 3.6 1 1 1 3 3 3 2 Serine rich protein interaction domain Mus7 PF09462.10 OWF44786.1 - 0.00013 21.0 0.7 0.049 12.5 0.4 2.4 1 1 1 2 2 2 2 Mus7/MMS22 family FAO_M PF16350.5 OWF44786.1 - 0.00016 21.9 10.5 4.1 7.8 0.3 5.5 1 1 7 8 8 8 2 FAD dependent oxidoreductase central domain NYD-SP28_assoc PF14775.6 OWF44786.1 - 0.00018 21.6 12.3 5.4 7.2 0.2 6.2 4 3 2 6 6 6 1 Sperm tail C-terminal domain HD_assoc PF13286.6 OWF44786.1 - 0.00035 21.0 1.9 23 5.6 0.0 4.1 1 1 5 6 6 6 0 Phosphohydrolase-associated domain GAS PF13851.6 OWF44786.1 - 0.00036 20.0 0.1 0.49 9.7 0.0 3.4 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding Allene_ox_cyc PF06351.11 OWF44786.1 - 0.00057 19.7 1.5 40 3.9 0.1 4.4 1 1 6 7 7 7 0 Allene oxide cyclase DUF3130 PF11328.8 OWF44786.1 - 0.00086 19.5 0.0 73 3.7 0.0 4.7 1 1 4 6 6 6 0 Protein of unknown function (DUF3130 Dak2 PF02734.17 OWF44786.1 - 0.0061 16.5 0.0 7.8 6.4 0.0 3.6 1 1 3 4 4 4 0 DAK2 domain DUF1451 PF07295.11 OWF44786.1 - 0.016 15.2 1.2 5.2 7.1 0.1 2.7 1 1 1 2 2 2 0 Zinc-ribbon containing domain Asp5 PF17000.5 OWF44786.1 - 0.018 15.2 11.1 22 5.3 0.0 5.5 2 2 5 7 7 7 0 Accessory secretory protein Sec, Asp5 INTS2 PF14750.6 OWF44786.1 - 0.035 11.7 0.6 0.41 8.1 0.1 1.8 1 1 1 2 2 2 0 Integrator complex subunit 2 Exonuc_VII_L PF02601.15 OWF44786.1 - 0.048 13.2 2.1 0.31 10.5 2.1 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Cdc6_C PF09079.11 OWF44786.1 - 0.065 13.2 19.2 61 3.7 0.1 7.5 1 1 7 8 8 8 0 CDC6, C terminal winged helix domain Spot_14 PF07084.12 OWF44786.1 - 0.067 13.3 2.0 6 7.0 0.1 3.5 1 1 1 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 RICH PF05062.12 OWF44786.1 - 0.12 12.7 0.8 26 5.3 0.0 3.6 1 1 3 4 4 4 0 RICH domain MetOD2 PF18548.1 OWF44786.1 - 0.14 12.3 1.4 25 5.1 0.1 4.0 1 1 4 5 5 5 0 Metanogen output domain 2 Nup35_RRM_2 PF14605.6 OWF44786.1 - 0.17 11.9 1.3 2.9e+02 1.6 0.0 5.2 5 1 0 5 5 5 0 Nup53/35/40-type RNA recognition motif Cep57_MT_bd PF06657.13 OWF44786.1 - 0.26 11.8 2.2 74 3.9 0.1 3.7 1 1 2 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Cor1 PF04803.12 OWF44786.1 - 0.37 11.0 9.2 14 5.9 0.6 3.6 1 1 3 4 4 4 0 Cor1/Xlr/Xmr conserved region Prominin PF05478.11 OWF44786.1 - 0.72 7.7 4.8 3.5 5.5 0.2 1.8 1 1 1 2 2 2 0 Prominin UCR_6-4kD PF08997.10 OWF44786.1 - 1.5 8.8 11.5 16 5.5 0.0 5.8 4 3 3 7 7 7 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein LHH PF14411.6 OWF44787.1 - 0.014 15.6 1.7 16 5.8 0.2 2.9 1 1 2 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH GAS PF13851.6 OWF44787.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.6 OWF44787.1 - 0.074 13.2 0.2 0.36 11.0 0.2 1.8 1 1 1 2 2 2 0 Sperm tail C-terminal domain P22_AR_C PF10548.9 OWF44787.1 - 0.11 12.6 0.2 0.84 9.8 0.2 2.1 1 1 1 2 2 2 0 P22AR C-terminal domain Kelch_5 PF13854.6 OWF44788.1 - 5.6e-40 134.7 28.6 0.00012 22.0 0.1 12.9 12 0 0 12 12 12 10 Kelch motif Kelch_4 PF13418.6 OWF44788.1 - 7.8e-38 128.3 25.2 3.6e-07 30.1 0.1 12.0 11 1 1 12 12 12 8 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF44788.1 - 1.6e-31 107.5 34.2 0.00042 20.5 0.0 12.4 13 0 0 13 13 12 9 Kelch motif Kelch_3 PF13415.6 OWF44788.1 - 5.4e-27 93.5 10.1 0.032 14.5 0.0 11.7 11 0 0 11 11 11 8 Galactose oxidase, central domain Kelch_1 PF01344.25 OWF44788.1 - 1.8e-24 85.0 29.7 0.0053 16.3 0.2 12.3 11 0 0 11 11 11 9 Kelch motif CUB PF00431.20 OWF44788.1 - 6e-21 74.9 4.5 5.7e-14 52.4 0.0 4.1 3 1 0 3 3 3 2 CUB domain Kelch_2 PF07646.15 OWF44788.1 - 2.3e-19 68.5 28.9 0.68 10.0 0.0 12.9 12 0 0 12 12 12 7 Kelch motif EGF_3 PF12947.7 OWF44788.1 - 2.4e-09 37.2 9.8 2.4e-09 37.2 9.8 12.7 13 3 1 14 14 6 2 EGF domain Laminin_EGF PF00053.24 OWF44788.1 - 7.9e-09 35.5 72.7 2.1e-05 24.6 18.7 20.7 15 8 5 20 20 12 4 Laminin EGF domain PSI PF01437.25 OWF44788.1 - 1.2e-08 35.3 41.3 9.4e-06 26.1 8.9 18.2 14 5 3 18 18 10 6 Plexin repeat EGF_CA PF07645.15 OWF44788.1 - 4.1e-07 30.1 27.8 6.4e-07 29.5 11.1 15.5 13 4 4 17 17 5 2 Calcium-binding EGF domain EGF_Tenascin PF18720.1 OWF44788.1 - 1.4e-05 25.0 7.3 1.4e-05 25.0 7.3 9.6 10 0 0 10 10 8 1 Tenascin EGF domain PSI_integrin PF17205.3 OWF44788.1 - 0.003 17.3 5.2 0.003 17.3 5.2 16.1 18 0 0 18 18 10 3 Integrin plexin domain EGF_2 PF07974.13 OWF44788.1 - 0.0049 17.2 13.4 0.0049 17.2 13.4 15.4 14 2 1 15 15 10 3 EGF-like domain Daxx PF03344.15 OWF44789.1 - 0.019 15.0 0.6 0.019 15.0 0.6 2.6 3 0 0 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain Methyltransf_12 PF08242.12 OWF44789.1 - 3 8.6 5.0 2.8 8.7 0.9 3.0 2 1 1 3 3 3 0 Methyltransferase domain INTS5_C PF14838.6 OWF44790.1 - 5.3e-173 577.4 18.5 7.7e-173 576.8 18.5 1.2 1 0 0 1 1 1 1 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 OWF44790.1 - 3.3e-73 245.7 0.8 1.1e-72 244.0 0.1 2.4 2 0 0 2 2 2 1 Integrator complex subunit 5 N-terminus fn3 PF00041.21 OWF44791.1 - 8.3e-05 22.9 1.8 5 7.5 0.1 4.0 3 0 0 3 3 3 3 Fibronectin type III domain TNFR_16_TM PF18422.1 OWF44791.1 - 0.91 9.5 5.1 2.5 8.1 5.1 1.8 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DHHC PF01529.20 OWF44792.1 - 1.4e-21 77.0 18.1 1.4e-21 77.0 18.1 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase UbiA PF01040.18 OWF44792.1 - 0.0028 17.0 1.9 0.0028 17.0 1.9 2.5 2 2 1 3 3 3 1 UbiA prenyltransferase family Halogen_Hydrol PF10112.9 OWF44792.1 - 0.15 12.1 0.1 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2101 PF09874.9 OWF44792.1 - 1.5 8.5 9.5 0.088 12.5 3.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF2663 PF10864.8 OWF44792.1 - 2.7 8.4 5.4 0.34 11.3 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) MRP-S31 PF15433.6 OWF44793.1 - 8.4e-55 186.7 2.4 9.8e-55 186.4 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 KH_1 PF00013.29 OWF44794.1 - 9e-40 134.3 21.8 5.5e-05 22.9 0.1 8.4 8 0 0 8 8 8 7 KH domain KH_2 PF07650.17 OWF44794.1 - 2.6e-13 49.6 36.0 0.045 13.6 0.2 10.2 6 2 3 9 9 8 6 KH domain Lactamase_B_2 PF12706.7 OWF44794.1 - 6.6e-09 35.6 0.8 0.51 9.8 0.0 4.3 1 1 3 4 4 4 4 Beta-lactamase superfamily domain TOC159_MAD PF11886.8 OWF44794.1 - 7.9e-08 31.5 5.7 0.064 12.1 0.1 4.2 2 1 2 4 4 4 3 Translocase of chloroplast 159/132, membrane anchor domain KH_5 PF13184.6 OWF44794.1 - 8.9e-07 28.9 23.5 0.74 9.9 0.1 7.6 8 0 0 8 8 8 2 NusA-like KH domain Phage_DNA_bind PF02303.17 OWF44794.1 - 1.5e-06 28.4 0.1 4.8 7.5 0.0 5.3 5 0 0 5 5 5 1 Helix-destabilising protein DUF2373 PF10180.9 OWF44794.1 - 5.7e-05 22.9 0.0 10 6.0 0.0 4.3 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2373) KH_4 PF13083.6 OWF44794.1 - 0.00041 20.2 9.7 21 5.1 0.0 7.4 7 0 0 7 7 7 0 KH domain Peptidase_M16_C PF05193.21 OWF44794.1 - 0.00054 20.0 9.7 0.73 9.8 1.4 5.5 4 2 0 5 5 5 1 Peptidase M16 inactive domain Myb_Cef PF11831.8 OWF44794.1 - 0.0062 16.1 12.3 0.49 9.9 0.1 5.3 6 0 0 6 6 6 1 pre-mRNA splicing factor component COPI_C PF06957.11 OWF44794.1 - 0.017 13.9 0.6 6.4 5.4 0.0 3.1 2 1 0 3 3 3 0 Coatomer (COPI) alpha subunit C-terminus Qua1 PF16274.5 OWF44794.1 - 0.018 14.9 15.7 6.1 6.8 0.1 5.7 6 0 0 6 6 6 0 Qua1 domain ZapA PF05164.13 OWF44794.1 - 0.041 14.3 13.2 50 4.4 0.2 5.7 6 0 0 6 6 5 0 Cell division protein ZapA ArsR PF09824.9 OWF44794.1 - 0.049 13.2 6.0 21 4.7 0.0 5.4 6 0 0 6 6 6 0 ArsR transcriptional regulator Phage_Coat_B PF05356.11 OWF44794.1 - 0.11 12.4 0.1 83 3.2 0.0 3.9 4 0 0 4 4 4 0 Phage Coat protein B FAD_binding_8 PF08022.12 OWF44794.1 - 0.15 12.1 1.1 95 3.1 0.0 4.1 2 1 1 4 4 4 0 FAD-binding domain Desmo_N PF06771.11 OWF44794.1 - 0.27 11.6 1.5 3.7 8.0 0.1 3.2 3 0 0 3 3 2 0 Viral Desmoplakin N-terminus DUF5320 PF17253.2 OWF44794.1 - 0.48 11.5 1.4 37 5.5 0.0 4.3 7 0 0 7 7 4 0 Family of unknown function (DUF5320) BCAS2 PF05700.11 OWF44794.1 - 4.9 6.8 10.3 75 2.9 0.1 5.3 6 0 0 6 6 6 0 Breast carcinoma amplified sequence 2 (BCAS2) NES_C_h PF18208.1 OWF44794.1 - 7.6 6.8 17.1 2.8 8.2 0.6 4.9 5 0 0 5 5 5 0 Nicking enzyme C-terminal middle helical domain Acetyltransf_18 PF18014.1 OWF44795.1 - 6.2e-16 58.4 0.0 9.6e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF44795.1 - 2.6e-06 27.7 0.0 8.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF44795.1 - 9.8e-06 25.5 0.0 0.098 12.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF44795.1 - 0.0074 16.7 0.0 0.23 11.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OWF44795.1 - 0.091 13.4 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DHHC PF01529.20 OWF44796.1 - 4.4e-36 123.9 3.3 4.4e-36 123.9 3.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase P5-ATPase PF12409.8 OWF44796.1 - 0.08 13.1 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter zf-C2H2 PF00096.26 OWF44797.1 - 2.7e-09 37.0 83.2 0.021 15.3 2.4 9.7 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF44797.1 - 4.5e-09 36.4 80.6 0.0029 18.3 4.0 10.2 10 0 0 10 10 10 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF44797.1 - 1.5e-05 25.2 18.5 0.00083 19.7 0.1 8.6 9 0 0 9 9 9 5 Zinc-finger double domain FOXP-CC PF16159.5 OWF44797.1 - 0.0011 19.5 53.0 0.064 13.9 0.6 9.0 5 4 4 9 9 9 3 FOXP coiled-coil domain zf-met PF12874.7 OWF44797.1 - 0.0035 17.7 28.5 0.0058 17.0 0.8 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF44797.1 - 0.011 16.0 32.7 0.15 12.4 1.7 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding SLIDE PF09111.10 OWF44797.1 - 0.061 13.4 0.4 0.68 10.0 0.0 2.7 3 0 0 3 3 3 0 SLIDE CCDC24 PF15669.5 OWF44797.1 - 0.58 10.0 6.7 3 7.7 1.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-H2C2_5 PF13909.6 OWF44797.1 - 1.3 8.8 55.2 0.3 10.9 0.2 6.4 6 0 0 6 6 6 0 C2H2-type zinc-finger domain AAT PF03417.16 OWF44798.1 - 8.2e-24 84.6 0.0 1.6e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Pkinase_Tyr PF07714.17 OWF44799.1 - 1.3e-61 208.2 0.0 2.2e-61 207.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF44799.1 - 3.6e-27 95.4 0.0 6.5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 OWF44799.1 - 1.2e-20 73.8 1.7 2.9e-11 43.8 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF44799.1 - 1.2e-17 63.7 0.2 7.4e-09 35.6 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF44799.1 - 2.1e-14 53.6 4.1 1.8e-06 28.2 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 OWF44799.1 - 2.7e-14 53.1 1.4 2.1e-06 27.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF44799.1 - 1.5e-06 28.3 7.8 0.093 12.9 0.0 5.6 3 3 1 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF44799.1 - 0.0017 18.3 0.3 0.008 16.2 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF44799.1 - 0.077 13.1 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain DUF4244 PF14029.6 OWF44799.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) PALP PF00291.25 OWF44800.1 - 1e-65 222.0 0.0 1.4e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 OWF44800.1 - 2.4e-10 40.7 0.7 9.4e-07 29.2 0.2 3.6 3 1 0 3 3 3 2 CBS domain Rho_N PF07498.12 OWF44800.1 - 0.27 11.2 1.2 6.3 6.8 0.8 2.8 2 1 0 2 2 2 0 Rho termination factor, N-terminal domain Lipase_GDSL_2 PF13472.6 OWF44801.1 - 0.00029 21.3 0.0 0.0003 21.2 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3143 PF11341.8 OWF44803.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Peptidase_M41 PF01434.18 OWF44804.1 - 4.1e-11 43.1 18.4 0.066 13.0 0.2 7.3 1 1 3 7 7 7 5 Peptidase family M41 T3SS_ExsE PF18286.1 OWF44804.1 - 3.5e-06 26.8 17.6 48 4.0 0.0 12.0 4 2 10 14 14 14 0 Type III secretion system ExsE HCNGP PF07818.13 OWF44804.1 - 4.6e-05 24.0 0.0 1.1e+02 3.5 0.0 7.4 1 1 5 7 7 7 0 HCNGP-like protein Nup35_RRM_2 PF14605.6 OWF44804.1 - 4.7e-05 23.3 0.2 37 4.4 0.0 8.7 10 3 1 11 11 11 0 Nup53/35/40-type RNA recognition motif APC_u13 PF16634.5 OWF44804.1 - 0.00087 19.1 0.2 2.1e+02 1.9 0.0 6.7 5 2 2 7 7 7 0 Unstructured region on APC between APC_crr and SAMP SRCR_2 PF15494.6 OWF44804.1 - 0.00091 19.7 0.0 37 5.0 0.0 4.7 1 1 3 5 5 5 0 Scavenger receptor cysteine-rich domain RecX PF02631.16 OWF44804.1 - 0.008 16.6 5.3 17 5.9 0.0 5.7 1 1 4 5 5 5 1 RecX family Sirohm_synth_M PF14824.6 OWF44804.1 - 0.16 11.4 1.7 2.2e+02 1.4 0.0 4.8 4 0 0 4 4 4 0 Sirohaem biosynthesis protein central RuvX PF03652.15 OWF44804.1 - 0.75 10.2 15.4 1.8e+02 2.5 0.1 7.7 2 2 5 8 8 8 0 Holliday junction resolvase RAG1_imp_bd PF12560.8 OWF44805.1 - 0.057 13.0 1.7 0.077 12.5 1.7 1.1 1 0 0 1 1 1 0 RAG1 importin binding Hydrolase_4 PF12146.8 OWF44806.1 - 1.5e-12 47.4 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OWF44806.1 - 1.1e-08 35.0 0.0 6.6e-05 22.7 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF44806.1 - 0.00019 22.1 0.0 0.00042 21.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OWF44806.1 - 0.0014 18.3 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OWF44806.1 - 0.15 11.6 0.0 0.58 9.7 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Phostensin_N PF13916.6 OWF44807.1 - 0.034 14.5 0.8 0.21 12.0 0.8 2.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal DUF3746 PF12562.8 OWF44807.1 - 6.7 6.7 9.3 9.8 6.2 0.5 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3746) POB3_N PF17292.2 OWF44808.1 - 2.3e-28 98.5 0.8 4.6e-23 81.5 0.4 2.6 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 OWF44808.1 - 6.3e-27 93.3 0.4 2.4e-26 91.4 0.1 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 OWF44808.1 - 4.2e-24 84.8 0.0 1.4e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like HMG_box PF00505.19 OWF44808.1 - 1.7e-17 63.5 3.4 1.7e-17 63.5 3.4 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF44808.1 - 6.5e-08 33.1 1.9 6.5e-08 33.1 1.9 2.3 2 0 0 2 2 2 1 HMG-box domain FGGY_N PF00370.21 OWF44809.1 - 3.1e-32 112.1 0.0 7.4e-32 110.8 0.0 1.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OWF44809.1 - 0.0097 15.4 0.0 0.89 9.0 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Cgr1 PF03879.14 OWF44810.1 - 2.3e-16 60.1 29.1 2.3e-16 60.1 29.1 2.0 2 0 0 2 2 2 1 Cgr1 family Macoilin PF09726.9 OWF44810.1 - 0.016 13.8 20.2 0.017 13.7 20.2 1.1 1 0 0 1 1 1 0 Macoilin family AAA_23 PF13476.6 OWF44810.1 - 0.59 10.6 14.5 0.79 10.2 14.5 1.3 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 OWF44810.1 - 2.2 8.0 14.8 2.7 7.8 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4140 PF13600.6 OWF44810.1 - 3.2 8.2 8.9 14 6.2 5.5 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RRM_1 PF00076.22 OWF44811.1 - 1.4e-11 44.1 0.1 4.8e-11 42.3 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 OWF44811.1 - 1e-07 31.1 7.6 1.4e-07 30.7 7.6 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others CUB PF00431.20 OWF44812.1 - 4.3e-71 236.3 0.9 1.6e-22 79.9 0.1 3.1 3 0 0 3 3 3 3 CUB domain Ldl_recept_a PF00057.18 OWF44812.1 - 1.9e-20 72.8 27.8 6.2e-12 45.5 12.1 3.0 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A CUB_2 PF02408.20 OWF44812.1 - 3.3e-10 39.8 0.2 0.00046 19.9 0.0 3.9 3 1 0 3 3 3 2 CUB-like domain MBT PF02820.18 OWF44812.1 - 0.062 13.7 0.9 0.21 11.9 0.1 2.3 3 0 0 3 3 3 0 mbt repeat Trypsin PF00089.26 OWF44813.1 - 2.9e-65 220.2 0.3 4e-65 219.7 0.3 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 OWF44813.1 - 6.3e-09 36.2 0.7 1.2e-08 35.2 0.1 1.8 2 0 0 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 OWF44813.1 - 2.8e-06 27.4 10.6 1.2e-05 25.4 10.6 2.2 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 OWF44813.1 - 0.0037 17.6 0.0 0.0061 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CLAMP PF14769.6 OWF44814.1 - 3.2e-38 130.1 2.8 6e-38 129.3 2.8 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Na_sulph_symp PF00939.19 OWF44815.1 - 4.3e-102 342.6 16.0 5.4e-102 342.3 16.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF44815.1 - 8.7e-38 130.2 21.6 7.2e-20 71.4 0.0 3.2 2 1 1 3 3 3 3 Citrate transporter Pro_dh PF01619.18 OWF44816.1 - 5.1e-84 282.3 0.3 1.9e-83 280.4 0.3 1.8 1 1 0 1 1 1 1 Proline dehydrogenase DUF871 PF05913.11 OWF44816.1 - 0.052 12.7 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Cellulase PF00150.18 OWF44816.1 - 0.089 12.2 0.0 0.97 8.8 0.0 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) PPR_3 PF13812.6 OWF44816.1 - 0.12 12.4 0.8 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain AP_endonuc_2 PF01261.24 OWF44816.1 - 0.17 11.3 0.0 0.4 10.1 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel CSTF_C PF14304.6 OWF44817.1 - 6.1e-07 28.9 15.0 3.4 7.3 0.1 7.0 1 1 5 8 8 8 5 Transcription termination and cleavage factor C-terminal CENP-M PF11111.8 OWF44818.1 - 3.2e-54 182.8 0.0 3.7e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Ras PF00071.22 OWF44818.1 - 0.026 14.1 0.2 0.56 9.8 0.0 2.3 2 1 0 2 2 2 0 Ras family Transmemb_17 PF09799.9 OWF44819.1 - 4.7e-25 88.2 15.1 6.8e-25 87.7 15.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein Na_Ca_ex PF01699.24 OWF44819.1 - 0.21 11.5 10.8 0.51 10.3 5.4 2.1 2 0 0 2 2 2 0 Sodium/calcium exchanger protein DUF3043 PF11241.8 OWF44819.1 - 1.4 8.9 7.4 0.16 12.0 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) SAP PF02037.27 OWF44820.1 - 4.9e-07 29.3 5.0 4.9e-07 29.3 5.0 2.5 2 0 0 2 2 2 1 SAP domain SNARE_assoc PF09335.11 OWF44820.1 - 6.2e-07 29.9 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein Drf_FH1 PF06346.12 OWF44820.1 - 0.0045 16.7 7.5 0.29 10.8 0.6 2.9 2 1 1 3 3 3 2 Formin Homology Region 1 CUB PF00431.20 OWF44821.1 - 8e-122 399.5 0.8 6.8e-22 77.9 0.0 6.5 6 0 0 6 6 6 6 CUB domain Trypsin PF00089.26 OWF44821.1 - 4.7e-61 206.4 2.1 8.9e-61 205.5 0.2 2.3 2 0 0 2 2 2 1 Trypsin MAM PF00629.23 OWF44821.1 - 1.7e-37 128.8 0.1 4.2e-20 72.3 0.0 3.8 3 0 0 3 3 3 2 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 OWF44821.1 - 2.6e-18 65.9 27.8 1.2e-10 41.5 6.2 3.2 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 OWF44821.1 - 1.6e-12 47.8 1.2 7.6e-12 45.6 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) SRCR_2 PF15494.6 OWF44821.1 - 2.9e-11 43.8 0.5 2.9e-11 43.8 0.5 2.6 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 OWF44821.1 - 6.9e-06 26.5 0.2 3e-05 24.4 0.2 2.1 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Cofilin_ADF PF00241.20 OWF44822.1 - 7.5e-26 90.3 0.8 9.3e-26 90.0 0.8 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pescadillo_N PF06732.11 OWF44823.1 - 5.7e-110 367.2 9.7 5.7e-110 367.2 9.7 2.1 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 OWF44823.1 - 1.7e-12 47.6 0.0 4.4e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OWF44823.1 - 9.6e-05 22.7 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OWF44823.1 - 0.0062 16.8 0.0 0.022 15.0 0.0 2.1 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain DNA_pol_phi PF04931.13 OWF44823.1 - 0.46 8.5 33.8 0.75 7.8 33.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OWF44823.1 - 0.57 8.4 27.2 1.2 7.4 27.2 1.5 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OWF44823.1 - 0.83 9.7 43.6 0.029 14.5 37.2 1.7 2 0 0 2 2 2 0 YL1 nuclear protein PI3K_1B_p101 PF10486.9 OWF44823.1 - 6.1 4.5 20.1 8.6 4.0 20.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PH PF00169.29 OWF44824.1 - 5.2e-11 43.0 0.0 1.3e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 OWF44824.1 - 0.0059 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SPACA9 PF15120.6 OWF44824.1 - 1.2 8.9 4.7 7.1 6.4 0.8 2.6 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 bZIP_2 PF07716.15 OWF44825.1 - 4.4e-15 55.5 13.0 9.6e-15 54.4 13.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF44825.1 - 8.7e-06 25.8 13.1 1.8e-05 24.8 13.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF44825.1 - 0.0053 17.3 6.9 0.0097 16.4 6.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor UPF0164 PF03687.13 OWF44826.1 - 0.0023 16.8 22.5 0.14 11.0 1.7 4.6 1 1 4 5 5 5 5 Uncharacterised protein family (UPF0164) PPE PF00823.19 OWF44826.1 - 0.0078 16.3 22.0 0.048 13.8 3.5 3.1 1 1 2 3 3 3 3 PPE family Phage_holin_3_2 PF04550.12 OWF44826.1 - 0.18 12.4 16.5 12 6.5 0.4 4.1 1 1 4 5 5 5 0 Phage holin family 2 SAD_SRA PF02182.17 OWF44826.1 - 4.8 6.8 20.8 21 4.7 1.6 5.2 1 1 3 4 4 4 0 SAD/SRA domain CAP PF00188.26 OWF44827.1 - 1.9e-22 80.4 1.0 3.9e-22 79.4 1.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Spermine_synth PF01564.17 OWF44828.1 - 8.2e-71 237.3 0.0 1.6e-70 236.4 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OWF44828.1 - 2.3e-25 88.2 0.1 3.9e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OWF44828.1 - 0.0029 18.3 0.0 0.0063 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF44828.1 - 0.014 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 OWF44829.1 - 6.5e-77 257.7 0.0 6.5e-77 257.7 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OWF44829.1 - 5.9e-09 36.3 0.0 2.2e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OWF44829.1 - 0.0041 17.2 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase BUD22 PF09073.10 OWF44829.1 - 7.2 5.8 70.8 0.055 12.8 41.9 2.3 2 0 0 2 2 2 0 BUD22 CHDCT2 PF08074.11 OWF44830.1 - 6.1e-87 290.2 0.2 6.1e-87 290.2 0.2 2.6 3 0 0 3 3 2 1 CHDCT2 (NUC038) domain DUF1086 PF06461.11 OWF44830.1 - 3.6e-60 201.8 0.0 3.6e-60 201.8 0.0 2.2 2 0 0 2 2 1 1 Domain of Unknown Function (DUF1086) SNF2_N PF00176.23 OWF44830.1 - 1.8e-59 201.2 0.0 4.1e-59 200.1 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1087 PF06465.13 OWF44830.1 - 1.5e-27 95.4 4.7 1.5e-27 95.4 4.7 3.9 3 1 0 3 3 1 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 OWF44830.1 - 1.4e-25 89.0 0.2 4.3e-25 87.4 0.2 1.8 1 0 0 1 1 1 1 CHDNT (NUC034) domain PHD PF00628.29 OWF44830.1 - 2.9e-21 75.1 26.7 8.5e-11 41.6 7.1 2.6 2 0 0 2 2 2 2 PHD-finger Helicase_C PF00271.31 OWF44830.1 - 1.4e-20 73.7 0.0 3.1e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OWF44830.1 - 3.4e-16 58.9 8.4 1e-13 51.0 1.9 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 OWF44830.1 - 0.011 16.0 0.0 0.043 14.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain PHD_2 PF13831.6 OWF44830.1 - 0.019 14.5 15.5 0.23 11.1 6.5 2.6 2 0 0 2 2 2 0 PHD-finger Rubredoxin PF00301.20 OWF44830.1 - 0.13 12.3 4.3 1.9 8.5 0.8 2.9 2 0 0 2 2 2 0 Rubredoxin zf-RanBP PF00641.18 OWF44830.1 - 0.67 9.3 7.3 6.9 6.1 0.4 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-HC5HC2H_2 PF13832.6 OWF44830.1 - 0.71 10.1 16.3 1.5 9.0 1.6 2.5 1 1 1 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.22 OWF44830.1 - 1.2 9.0 14.7 6.1 6.8 1.3 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ_CXXCXGXG PF00684.19 OWF44830.1 - 4.2 7.8 13.5 1.8 9.0 5.2 2.7 2 0 0 2 2 2 0 DnaJ central domain zf-C2H2 PF00096.26 OWF44831.1 - 1.6e-26 91.2 72.0 0.00013 22.2 2.1 10.6 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF44831.1 - 4.9e-26 89.2 68.6 0.0054 17.5 3.3 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF44831.1 - 1.3e-19 69.6 56.5 8e-05 22.9 0.6 11.5 12 0 0 12 12 12 6 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 OWF44831.1 - 5.1e-06 26.3 17.6 0.078 12.9 0.0 6.2 5 3 0 5 5 5 2 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 OWF44831.1 - 0.00015 21.4 3.5 0.00015 21.4 3.5 8.7 9 1 1 10 10 9 4 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OWF44831.1 - 0.0021 17.9 2.2 0.0021 17.9 2.2 6.5 6 0 0 6 6 6 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 OWF44831.1 - 0.0025 17.9 34.9 2.9 8.1 3.2 8.7 6 4 3 9 9 9 2 Zinc ribbon domain zinc_ribbon_15 PF17032.5 OWF44831.1 - 0.0026 18.5 28.6 0.67 10.8 0.8 6.3 3 2 2 6 6 6 3 zinc-ribbon family zf-RING_7 PF02591.15 OWF44831.1 - 0.032 14.4 4.5 12 6.2 0.3 4.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-C2H2_jaz PF12171.8 OWF44831.1 - 0.04 14.2 27.6 0.074 13.4 1.9 7.0 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 OWF44831.1 - 0.1 12.2 0.1 0.1 12.2 0.1 7.8 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger Baculo_IE-1 PF05290.11 OWF44831.1 - 0.2 11.6 10.8 1.5 8.8 0.1 4.5 4 0 0 4 4 4 0 Baculovirus immediate-early protein (IE-0) HalOD2 PF18547.1 OWF44831.1 - 0.25 11.3 5.5 20 5.2 0.1 4.8 4 0 0 4 4 4 0 Halobacterial output domain 2 zf-C2H2_2 PF12756.7 OWF44831.1 - 0.66 10.3 51.8 20 5.6 5.4 9.7 3 2 5 9 9 9 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 OWF44831.1 - 1.1 9.5 46.0 0.1 12.7 7.6 7.0 2 2 4 6 6 6 0 FYVE zinc finger zf-C2H2_6 PF13912.6 OWF44831.1 - 2.4 8.3 54.5 0.27 11.3 0.2 10.0 10 0 0 10 10 10 0 C2H2-type zinc finger zf_Hakai PF18408.1 OWF44831.1 - 2.6 7.8 9.4 0.1 12.3 0.3 3.2 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain DUF2256 PF10013.9 OWF44831.1 - 5.9 7.1 34.6 2.8 8.1 0.1 8.0 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) MFS_1 PF07690.16 OWF44832.1 - 4.2e-30 104.9 21.0 6.3e-29 101.0 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OWF44832.1 - 1.9e-16 60.3 3.5 1.9e-16 60.3 3.5 2.1 1 1 1 2 2 2 1 Nodulin-like Pentapeptide_4 PF13599.6 OWF44833.1 - 0.0019 18.3 0.0 15 5.9 0.0 3.6 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Sarcolipin PF05366.11 OWF44834.1 - 1.6 8.5 7.4 0.17 11.6 2.2 1.9 2 0 0 2 2 2 0 Sarcolipin WASH-7_mid PF14744.6 OWF44835.1 - 0.0041 16.3 34.1 4.6 6.2 0.1 11.2 1 1 10 11 11 11 3 WASH complex subunit 7 SopE_GEF PF07487.13 OWF44835.1 - 0.024 14.7 80.8 4.1 7.5 0.8 14.9 1 1 13 17 17 17 0 SopE GEF domain SAC3 PF12209.8 OWF44835.1 - 1.4 9.1 36.0 29 4.9 0.2 14.6 2 1 12 18 18 18 0 Leucine permease transcriptional regulator helical domain LepB_N PF18640.1 OWF44835.1 - 5.6 6.5 85.2 12 5.5 0.8 16.8 1 1 15 16 16 16 0 LepB N-terminal domain PhyH PF05721.13 OWF44836.1 - 0.00014 22.2 0.1 0.00023 21.5 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 OWF44837.1 - 4.7e-12 46.6 0.5 1.3e-11 45.2 0.5 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2715 PF10895.8 OWF44838.1 - 0.0012 18.5 0.2 0.26 10.9 0.2 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2715) PhyH PF05721.13 OWF44839.1 - 4.5e-10 40.1 0.8 1.1e-09 38.8 0.8 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OWF44839.1 - 7.7e-05 21.6 0.4 0.003 16.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) MucBP_2 PF17965.1 OWF44839.1 - 0.16 12.6 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Mucin binding domain Pkinase_Tyr PF07714.17 OWF44840.1 - 7.5e-86 287.6 0.0 1.1e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF44840.1 - 5.3e-44 150.6 0.0 8.2e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GTPase_binding PF09027.10 OWF44840.1 - 1.1e-22 79.7 0.3 3.7e-22 78.1 0.3 1.9 1 0 0 1 1 1 1 GTPase binding SH3_9 PF14604.6 OWF44840.1 - 1.2e-06 28.2 0.2 2.6e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF44840.1 - 1.7e-05 24.3 0.2 4.2e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF44840.1 - 1.8e-05 24.3 0.0 3.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UBA_4 PF14555.6 OWF44840.1 - 0.00018 21.3 0.1 0.17 11.7 0.1 2.4 2 0 0 2 2 2 2 UBA-like domain Kinase-like PF14531.6 OWF44840.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HBS1_N PF08938.10 OWF44840.1 - 0.0027 18.0 0.0 0.0089 16.3 0.0 1.9 1 0 0 1 1 1 1 HBS1 N-terminus Haspin_kinase PF12330.8 OWF44840.1 - 0.049 12.6 0.0 0.098 11.6 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OWF44841.1 - 6.6e-17 61.7 0.0 4.2e-16 59.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 OWF44841.1 - 1.2e-12 48.1 12.0 0.00063 20.5 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.22 OWF44841.1 - 6.1e-07 29.2 0.0 0.21 11.9 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat ANAPC4_WD40 PF12894.7 OWF44841.1 - 0.00027 21.2 1.8 1.2 9.5 0.1 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 OWF44841.1 - 0.0003 20.2 0.0 0.0035 16.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 OWF44841.1 - 0.0019 18.3 0.1 0.13 12.3 0.1 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OWF44841.1 - 0.013 16.0 0.0 2.4 8.8 0.0 3.7 4 1 1 5 5 5 0 HEAT-like repeat PAX PF00292.18 OWF44842.1 - 1.2e-72 241.8 1.4 1.9e-72 241.0 1.4 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 OWF44842.1 - 1.6e-22 79.1 5.7 3.6e-22 78.0 5.7 1.6 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 OWF44842.1 - 3.9e-07 29.7 1.5 2.3e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 OWF44842.1 - 2.3e-05 24.9 4.3 0.0019 18.8 0.0 2.9 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 OWF44842.1 - 2.8e-05 24.1 1.5 0.00017 21.6 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.11 OWF44842.1 - 9e-05 22.3 0.8 9e-05 22.3 0.8 2.5 3 0 0 3 3 3 1 Homeobox KN domain HTH_29 PF13551.6 OWF44842.1 - 0.0002 21.3 0.4 0.00076 19.5 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix OAR PF03826.17 OWF44842.1 - 0.0078 16.0 3.4 0.022 14.6 3.4 1.8 1 0 0 1 1 1 1 OAR domain MarR_2 PF12802.7 OWF44842.1 - 0.075 12.9 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 MarR family Ank_2 PF12796.7 OWF44843.1 - 1.3e-28 99.3 0.1 2.9e-10 40.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF44843.1 - 9.3e-25 84.0 1.1 8.7e-06 25.7 0.0 5.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OWF44843.1 - 6.7e-19 68.0 0.1 9.6e-07 29.2 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF44843.1 - 4.4e-18 65.1 1.3 1.2e-05 25.5 0.0 4.8 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF44843.1 - 9.1e-17 60.7 0.7 0.00055 20.3 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat SOCS_box PF07525.16 OWF44843.1 - 3.7e-08 33.6 2.8 1e-07 32.2 2.8 1.8 1 0 0 1 1 1 1 SOCS box Exc PF07825.11 OWF44843.1 - 0.004 17.1 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 Excisionase-like protein MFS_1 PF07690.16 OWF44844.1 - 1.2e-14 54.0 24.6 1.2e-14 54.0 24.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM144 PF07857.12 OWF44845.1 - 3.7e-90 302.3 12.4 4.8e-90 301.9 12.4 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 OWF44845.1 - 3.4e-07 29.9 14.7 1.2e-06 28.1 1.8 2.4 2 1 0 2 2 2 2 Sugar transport protein Nsp2a_N PF17896.1 OWF44845.1 - 0.13 11.5 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Ion_trans PF00520.31 OWF44846.1 - 2.2e-27 95.9 21.5 2.2e-27 95.9 21.5 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 OWF44846.1 - 6.2e-14 51.7 7.6 6.2e-14 51.7 7.6 2.6 3 0 0 3 3 3 1 Ion channel DUF202 PF02656.15 OWF44846.1 - 0.058 13.8 1.6 8.5 6.9 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) TRP_2 PF08344.11 OWF44847.1 - 1.9e-20 72.9 0.9 6.5e-20 71.1 0.9 2.0 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 OWF44847.1 - 8.6e-13 48.1 14.3 2.2e-12 46.7 14.3 1.7 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 OWF44847.1 - 0.00065 20.2 0.0 0.21 12.2 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) PKD_channel PF08016.12 OWF44847.1 - 0.0011 17.7 12.8 0.088 11.5 4.0 2.5 2 0 0 2 2 2 2 Polycystin cation channel Ank_3 PF13606.6 OWF44847.1 - 0.0039 17.6 2.7 28 5.7 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 OWF44847.1 - 0.15 12.5 0.0 35 4.9 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Hydantoinase_B PF02538.14 OWF44847.1 - 4 5.7 5.0 4.7 5.5 1.8 2.0 1 1 0 2 2 2 0 Hydantoinase B/oxoprolinase P66_CC PF16563.5 OWF44847.1 - 5.3 6.7 7.6 0.29 10.8 1.1 2.3 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 ING PF12998.7 OWF44847.1 - 8.2 7.1 11.4 8.3 7.1 0.1 2.9 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Tcp10_C PF07202.13 OWF44848.1 - 2.8e-05 24.1 0.0 0.00024 21.1 0.0 2.4 1 1 0 1 1 1 1 T-complex protein 10 C-terminus TubC_N PF18563.1 OWF44848.1 - 0.00015 21.6 0.0 36 4.4 0.0 5.8 2 2 3 6 6 6 0 TubC N-terminal docking domain FecR PF04773.13 OWF44848.1 - 0.0018 18.9 1.2 1 10.0 0.1 3.3 2 1 2 4 4 4 1 FecR protein Furin-like_2 PF15913.5 OWF44848.1 - 0.021 15.0 8.5 2.1 8.5 1.1 2.7 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich DUF2218 PF09981.9 OWF44848.1 - 0.15 12.5 0.0 43 4.6 0.0 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) zf-LSD1 PF06943.12 OWF44848.1 - 0.26 11.2 2.9 1.8 8.5 0.0 3.7 3 2 1 4 4 4 0 LSD1 zinc finger RtxA PF07634.11 OWF44848.1 - 0.36 11.4 48.1 1.9 9.2 0.6 9.5 3 2 4 7 7 7 0 RtxA repeat DUF5114 PF17141.4 OWF44848.1 - 0.45 11.1 6.2 27 5.4 6.2 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5114) Lipocalin_4 PF13648.6 OWF44848.1 - 0.61 11.1 10.1 2.4e+02 2.8 9.9 3.4 1 1 0 1 1 1 0 Lipocalin-like domain Sar8_2 PF03058.14 OWF44848.1 - 0.85 10.2 4.8 30 5.3 0.7 3.3 1 1 2 3 3 3 0 Sar8.2 family Imm12 PF15560.6 OWF44848.1 - 3.1 7.7 13.7 34 4.4 0.2 5.2 1 1 3 6 6 6 0 Immunity protein 12 Fascin PF06268.13 OWF44849.1 - 0.048 13.9 0.0 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 Fascin domain Rubella_E1 PF05748.11 OWF44849.1 - 0.051 12.5 1.8 2.2 7.1 0.2 2.2 1 1 1 2 2 2 0 Rubella membrane glycoprotein E1 BRX_assoc PF16627.5 OWF44849.1 - 0.55 10.4 4.4 37 4.6 0.3 3.2 1 1 1 3 3 3 0 Unstructured region between BRX_N and BRX domain NACHT_sigma PF17106.5 OWF44850.1 - 0.0032 17.6 0.0 2.3 8.4 0.0 3.3 3 1 0 3 3 3 1 Sigma domain on NACHT-NTPases NifT PF06988.11 OWF44850.1 - 0.23 11.3 0.3 59 3.5 0.0 3.4 3 2 0 3 3 3 0 NifT/FixU protein Rubella_E1 PF05748.11 OWF44850.1 - 0.37 9.6 11.2 1.4 7.8 0.9 3.0 1 1 2 3 3 3 0 Rubella membrane glycoprotein E1 Bombesin PF02044.17 OWF44850.1 - 8.7 6.7 12.2 1.4e+02 2.9 0.0 5.5 6 0 0 6 6 6 0 Bombesin-like peptide ALC PF17527.2 OWF44851.1 - 0.0002 21.1 1.9 1.9 8.1 0.0 4.9 1 1 5 6 6 6 2 Phage ALC protein DUF896 PF05979.12 OWF44851.1 - 0.0081 16.0 2.1 20 5.1 0.0 4.3 4 1 0 4 4 4 2 Bacterial protein of unknown function (DUF896) DUF3997 PF13162.6 OWF44851.1 - 0.092 13.0 0.1 28 5.1 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3997) DUF780 PF05611.11 OWF44851.1 - 4.6 8.1 6.9 65 4.4 0.1 4.5 4 2 2 6 6 6 0 Caenorhabditis elegans protein of unknown function (DUF780) MFS_1 PF07690.16 OWF44852.1 - 8.4e-41 140.0 17.5 2.7e-29 102.2 2.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF44852.1 - 2.2e-07 30.1 13.5 1.6e-06 27.3 5.8 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OWF44852.1 - 2.4e-05 23.4 10.5 0.01 14.8 2.0 2.9 2 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 OWF44852.1 - 0.0015 16.9 14.1 0.024 12.9 0.4 3.5 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family DctQ PF04290.12 OWF44852.1 - 0.017 15.1 0.9 0.017 15.1 0.9 3.7 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2660 PF10859.8 OWF44852.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF4293 PF14126.6 OWF44852.1 - 0.93 9.7 5.9 0.4 10.9 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) DUF4131 PF13567.6 OWF44852.1 - 0.97 9.1 7.0 1.1 8.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) LacY_symp PF01306.19 OWF44852.1 - 1.4 7.7 10.3 0.25 10.1 1.6 2.3 2 0 0 2 2 2 0 LacY proton/sugar symporter Lipoxygenase PF00305.19 OWF44853.1 - 1.4e-56 192.3 0.0 2.2e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase PI-TkoII_IV PF18714.1 OWF44853.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Myb_DNA-binding PF00249.31 OWF44854.1 - 8.3e-10 38.7 0.4 2.4e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 OWF44854.1 - 3.4e-09 36.4 8.0 7.1e-09 35.3 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OWF44854.1 - 0.0042 17.3 0.3 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_2 PF03107.16 OWF44854.1 - 0.0064 16.8 8.9 0.018 15.4 8.9 1.8 1 0 0 1 1 1 1 C1 domain RcbX PF02341.15 OWF44854.1 - 0.042 14.1 0.2 0.079 13.2 0.2 1.4 1 0 0 1 1 1 0 RbcX protein Nucleoporin_C PF03177.14 OWF44855.1 - 2.2e-35 122.5 12.5 1.4e-32 113.2 12.5 2.4 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OWF44855.1 - 1e-14 54.2 0.0 2.2e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Nup133 N terminal like baeRF_family11 PF18855.1 OWF44855.1 - 0.015 15.6 0.2 0.041 14.2 0.2 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 CoA_transf_3 PF02515.17 OWF44855.1 - 0.082 12.0 0.2 0.21 10.7 0.2 1.7 2 0 0 2 2 2 0 CoA-transferase family III DCAF15_WD40 PF14939.6 OWF44856.1 - 4.3e-67 225.9 0.1 4.3e-67 225.9 0.1 1.5 2 0 0 2 2 2 1 DDB1-and CUL4-substrate receptor 15, WD repeat Sbi-IV PF11621.8 OWF44857.1 - 1.3e-05 25.4 42.5 9 6.7 0.0 14.9 3 2 14 17 17 17 5 C3 binding domain 4 of IgG-bind protein SBI HMMR_C PF15908.5 OWF44857.1 - 0.41 10.9 5.8 0.54 10.5 3.8 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Peptidase_M1 PF01433.20 OWF44858.1 - 9.3e-89 296.7 0.4 1.8e-88 295.8 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OWF44858.1 - 1.3e-79 268.1 2.1 2.1e-79 267.3 1.4 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OWF44858.1 - 2.2e-44 151.8 0.5 2.2e-44 151.8 0.5 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 OWF44858.1 - 0.047 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative aminopeptidase DUF3224 PF11528.8 OWF44858.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) Endotoxin_C PF03944.14 OWF44858.1 - 0.2 12.0 2.5 0.92 9.8 0.3 2.7 2 1 0 2 2 2 0 delta endotoxin Peptidase_M1 PF01433.20 OWF44859.1 - 2.1e-82 275.9 0.4 3.8e-82 275.1 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OWF44859.1 - 1.4e-72 244.9 0.2 2.7e-72 244.0 0.2 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OWF44859.1 - 3.8e-48 164.2 1.6 3.8e-48 164.2 1.6 2.1 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 OWF44859.1 - 0.018 14.5 0.0 0.059 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative aminopeptidase Redoxin PF08534.10 OWF44860.1 - 6.6e-36 123.2 0.1 8.1e-36 122.9 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OWF44860.1 - 2.4e-10 40.4 0.0 2.8e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family ABC2_membrane PF01061.24 OWF44861.1 - 1.2e-27 96.7 15.2 1.8e-27 96.2 15.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OWF44861.1 - 2e-25 89.9 0.1 3.1e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF44861.1 - 5.1e-05 22.8 0.0 0.0014 18.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OWF44861.1 - 0.0001 22.3 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OWF44861.1 - 0.00013 22.4 0.0 0.00025 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OWF44861.1 - 0.0002 22.0 0.0 0.00031 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF44861.1 - 0.00035 20.2 0.7 0.0013 18.5 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OWF44861.1 - 0.00054 19.9 0.1 0.27 11.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OWF44861.1 - 0.029 14.5 0.3 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 OWF44861.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Asp-Al_Ex PF06826.12 OWF44861.1 - 1.7 8.4 7.8 0.38 10.5 4.2 1.7 2 0 0 2 2 2 0 Predicted Permease Membrane Region ABC2_membrane_3 PF12698.7 OWF44861.1 - 2.9 6.9 12.2 7.1 5.6 12.2 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein FA_desaturase PF00487.24 OWF44861.1 - 8.1 6.2 8.0 0.57 10.0 0.6 2.2 1 1 1 2 2 2 0 Fatty acid desaturase ABC_tran PF00005.27 OWF44862.1 - 2.6e-26 92.7 0.0 4.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OWF44862.1 - 4.1e-23 81.9 19.6 4.1e-23 81.9 19.6 1.6 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 OWF44862.1 - 4.5e-05 23.4 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 OWF44862.1 - 0.00012 22.0 0.1 0.00012 22.0 0.1 2.7 3 0 0 3 3 2 1 CDR ABC transporter AAA_23 PF13476.6 OWF44862.1 - 0.0012 19.4 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF44862.1 - 0.0021 17.8 0.1 0.0047 16.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 OWF44862.1 - 0.0026 17.7 0.1 0.0047 16.9 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OWF44862.1 - 0.003 17.9 0.0 0.0063 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OWF44862.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 OWF44862.1 - 0.011 15.2 0.2 0.4 10.1 0.2 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OWF44862.1 - 0.1 12.7 1.7 0.5 10.4 0.8 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 OWF44862.1 - 0.16 11.5 0.0 0.47 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain TAFH PF07531.14 OWF44862.1 - 0.19 11.9 0.1 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 NHR1 homology to TAF ABC2_membrane PF01061.24 OWF44864.1 - 6.4e-30 104.1 22.1 6.4e-30 104.1 22.1 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OWF44864.1 - 4e-26 92.2 0.1 6.2e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF44864.1 - 1.2e-09 38.4 2.1 1.4e-06 28.3 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OWF44864.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OWF44864.1 - 0.031 14.0 0.6 0.031 14.0 0.6 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OWF44864.1 - 0.035 14.5 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 OWF44864.1 - 0.073 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SMC_N PF02463.19 OWF44864.1 - 0.22 11.0 0.2 1 8.7 0.2 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain TMEM154 PF15102.6 OWF44865.1 - 2e-05 24.5 1.4 2e-05 24.5 1.4 2.2 3 0 0 3 3 3 1 TMEM154 protein family LRR19-TM PF15176.6 OWF44865.1 - 0.0038 17.2 0.2 0.049 13.6 0.0 2.3 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain ECSCR PF15820.5 OWF44865.1 - 0.0047 16.7 0.1 0.0095 15.7 0.1 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator DAG1 PF05454.11 OWF44865.1 - 0.0079 15.6 0.7 0.0079 15.6 0.7 2.0 2 1 1 3 3 3 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Baculo_F PF12259.8 OWF44865.1 - 0.0088 14.6 1.1 0.012 14.1 1.1 1.1 1 0 0 1 1 1 1 Baculovirus F protein DUF4711 PF15829.5 OWF44865.1 - 0.037 14.0 0.7 0.037 14.0 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) Pox_EPC_I2-L1 PF12575.8 OWF44865.1 - 0.24 11.6 0.7 0.48 10.7 0.7 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF4366 PF14283.6 OWF44865.1 - 0.3 11.1 5.1 2 8.5 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 OWF44865.1 - 6.5 6.5 5.8 0.77 9.6 1.7 1.4 2 0 0 2 2 2 0 Rifin EphA2_TM PF14575.6 OWF44865.1 - 7.3 7.6 5.7 24 5.9 5.8 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sec3-PIP2_bind PF15277.6 OWF44866.1 - 4.7e-06 26.6 3.5 40 4.4 0.1 7.5 1 1 8 9 9 9 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Nucleoporin_FG PF13634.6 OWF44866.1 - 0.00013 22.8 11.6 3.9 8.4 1.5 4.0 1 1 1 2 2 2 1 Nucleoporin FG repeat region Topo_Zn_Ribbon PF08272.11 OWF44866.1 - 0.00014 21.5 31.5 2.3e+02 1.6 0.0 15.2 17 0 0 17 17 17 0 Topoisomerase I zinc-ribbon-like DUF4642 PF15484.6 OWF44866.1 - 1 9.6 9.0 26 5.0 1.4 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4642) Kunitz_BPTI PF00014.23 OWF44867.1 - 3.5e-35 120.0 26.9 1.8e-17 63.3 11.4 2.3 1 1 1 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 OWF44868.1 - 5.6e-12 45.7 29.1 1.1e-11 44.8 9.4 3.3 2 1 1 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 OWF44869.1 - 2.3e-19 69.4 24.1 7.7e-15 54.9 10.6 2.1 1 1 1 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF2207 PF09972.9 OWF44870.1 - 0.036 12.8 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Neur_chan_LBD PF02931.23 OWF44871.1 - 1.5e-42 145.5 0.2 2.1e-42 145.0 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44871.1 - 2.2e-19 70.5 13.4 3.4e-14 53.5 9.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region SCAMP PF04144.13 OWF44871.1 - 0.04 14.2 0.7 0.04 14.2 0.7 2.2 2 1 0 2 2 2 0 SCAMP family Neur_chan_LBD PF02931.23 OWF44872.1 - 1.2e-74 250.4 8.2 6e-42 143.5 0.6 2.4 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44872.1 - 2.4e-46 158.7 34.8 2.9e-23 83.2 8.5 4.1 2 2 2 4 4 4 4 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF44873.1 - 4.1e-42 144.1 1.3 5.5e-42 143.6 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44873.1 - 3.3e-19 69.9 12.1 2.2e-18 67.2 7.7 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF44874.1 - 1.3e-100 335.2 12.3 9.3e-37 126.6 0.7 3.5 3 1 1 4 4 4 3 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44874.1 - 1.1e-67 228.6 24.0 1.2e-23 84.5 4.7 4.7 3 2 1 4 4 4 4 Neurotransmitter-gated ion-channel transmembrane region CsgG PF03783.14 OWF44874.1 - 0.042 13.1 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Curli production assembly/transport component CsgG E2R135 PF11570.8 OWF44874.1 - 0.058 13.7 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 LRR_8 PF13855.6 OWF44875.1 - 1.7e-22 78.9 21.0 1.2e-11 44.2 10.9 4.3 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OWF44875.1 - 6.5e-20 70.9 27.8 3.2e-07 30.5 6.4 4.7 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF44875.1 - 2.2e-08 33.8 4.4 7.2e-05 22.4 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OWF44875.1 - 4e-07 29.7 25.3 0.38 11.5 0.6 7.4 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 OWF44875.1 - 0.0014 18.5 26.9 0.61 10.3 0.8 7.2 7 0 0 7 7 7 2 Leucine Rich repeat TEP1_N PF05386.11 OWF44875.1 - 0.0098 15.5 2.5 0.03 13.9 2.5 1.8 1 0 0 1 1 1 1 TEP1 N-terminal domain LRR_5 PF13306.6 OWF44875.1 - 0.011 15.7 1.8 0.18 11.7 0.2 2.3 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 OWF44875.1 - 0.015 15.3 0.1 6.6 6.9 0.0 3.5 2 2 2 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain NTPase_1 PF03266.15 OWF44876.1 - 5.5e-53 179.3 0.0 6.8e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 NTPase AAA PF00004.29 OWF44876.1 - 3.4e-07 30.7 0.0 7.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF44876.1 - 1.1e-06 29.2 0.1 2e-06 28.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OWF44876.1 - 1.5e-06 28.6 0.1 5e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OWF44876.1 - 4e-06 26.9 0.0 0.00045 20.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF44876.1 - 1.1e-05 25.7 0.3 7.3e-05 23.1 0.3 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OWF44876.1 - 1.3e-05 25.1 0.1 4.4e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 OWF44876.1 - 4.8e-05 23.2 0.0 8.7e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OWF44876.1 - 5.2e-05 23.0 0.0 0.0004 20.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OWF44876.1 - 0.00014 21.9 0.1 0.013 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OWF44876.1 - 0.0014 19.0 0.0 0.0036 17.7 0.0 1.7 2 0 0 2 2 1 1 RNA helicase ATPase_2 PF01637.18 OWF44876.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OWF44876.1 - 0.0022 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OWF44876.1 - 0.0046 17.0 0.0 0.0071 16.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OWF44876.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 OWF44876.1 - 0.0055 16.3 0.1 0.029 14.0 0.1 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OWF44876.1 - 0.0062 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OWF44876.1 - 0.0093 16.5 0.0 0.014 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 OWF44876.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OWF44876.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF44876.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OWF44876.1 - 0.014 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 OWF44876.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.22 OWF44876.1 - 0.015 14.9 0.1 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 6PF2K PF01591.18 OWF44876.1 - 0.017 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Mg_chelatase PF01078.21 OWF44876.1 - 0.024 14.0 0.1 0.05 13.0 0.0 1.5 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 OWF44876.1 - 0.024 13.6 0.1 0.047 12.6 0.1 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Rad17 PF03215.15 OWF44876.1 - 0.026 14.5 0.6 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 OWF44876.1 - 0.026 14.7 0.1 0.051 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 OWF44876.1 - 0.027 13.9 0.1 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 OWF44876.1 - 0.032 14.0 0.1 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 OWF44876.1 - 0.041 13.7 0.3 0.092 12.5 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.11 OWF44876.1 - 0.043 13.7 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OWF44876.1 - 0.051 12.6 0.1 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 OWF44876.1 - 0.052 12.7 0.1 0.089 12.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 OWF44876.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Viral_helicase1 PF01443.18 OWF44876.1 - 0.072 12.8 0.3 1.2 8.8 0.3 2.1 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 OWF44876.1 - 0.08 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 OWF44876.1 - 0.083 12.0 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain MobB PF03205.14 OWF44876.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 OWF44876.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF853 PF05872.12 OWF44876.1 - 0.15 10.7 0.2 0.25 9.9 0.1 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) HlyIII PF03006.20 OWF44877.1 - 8.6e-33 113.9 22.6 1.4e-32 113.2 22.6 1.3 1 0 0 1 1 1 1 Haemolysin-III related Glyco_transf_4 PF13439.6 OWF44877.1 - 0.0095 16.0 0.1 0.02 14.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Sushi PF00084.20 OWF44878.1 - 4.5e-48 161.7 45.2 3.7e-11 43.4 1.6 7.6 7 0 0 7 7 7 7 Sushi repeat (SCR repeat) AMOP PF03782.17 OWF44878.1 - 1.5e-22 80.3 3.0 2.9e-22 79.3 3.0 1.5 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 OWF44878.1 - 6.8e-22 78.2 0.5 2e-21 76.7 0.5 1.9 1 0 0 1 1 1 1 Nidogen-like VWD PF00094.25 OWF44878.1 - 1.4e-14 54.7 1.8 4.2e-14 53.1 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type D domain VIT PF08487.10 OWF44879.1 - 8.2e-25 87.2 2.8 2.5e-24 85.6 2.8 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OWF44879.1 - 5.5e-21 75.6 0.0 1.2e-20 74.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF44879.1 - 1.4e-17 64.2 0.0 4.3e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF44879.1 - 4.3e-16 59.2 0.0 7.9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF44879.1 - 0.00039 19.9 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Peptidase_S49_N PF08496.10 OWF44879.1 - 0.0011 19.0 0.0 0.0039 17.3 0.0 1.9 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF2201 PF09967.9 OWF44879.1 - 0.0047 17.1 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 VWA-like domain (DUF2201) vWA-TerF-like PF10138.9 OWF44879.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus CobT_C PF11775.8 OWF44879.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Sec23_trunk PF04811.15 OWF44879.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain VIT PF08487.10 OWF44880.1 - 4.6e-24 84.8 2.7 1.3e-23 83.3 2.7 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OWF44880.1 - 1.5e-21 77.4 0.2 3.2e-21 76.4 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF44880.1 - 2.2e-16 60.2 0.0 3.9e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF44880.1 - 8.3e-16 58.6 0.1 2e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF44880.1 - 0.00018 20.9 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 OWF44880.1 - 0.0016 18.5 0.1 0.0047 17.1 0.1 1.9 1 1 0 1 1 1 1 VWA-like domain (DUF2201) Peptidase_S49_N PF08496.10 OWF44880.1 - 0.0099 15.9 0.0 0.042 13.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 N-terminal VIT PF08487.10 OWF44881.1 - 1.1e-07 32.0 0.5 1.3e-07 31.8 0.5 1.1 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OWF44882.1 - 1.6e-16 61.1 0.0 4.3e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF44882.1 - 2.2e-15 56.9 0.0 6.2e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF44882.1 - 1.2e-08 35.5 0.0 4.2e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF44882.1 - 0.0024 17.3 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein BRAP2 PF07576.12 OWF44883.1 - 2.8e-31 107.6 0.0 5.6e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 OWF44883.1 - 3.8e-20 72.0 8.4 9.9e-20 70.6 8.4 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 OWF44883.1 - 7.1e-08 32.7 8.9 7.1e-08 32.7 8.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OWF44883.1 - 6.2e-06 26.0 4.2 6.2e-06 26.0 4.2 2.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF44883.1 - 6.3e-06 25.9 8.6 6.3e-06 25.9 8.6 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF44883.1 - 4.1e-05 23.8 6.4 4.1e-05 23.8 6.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OWF44883.1 - 4.7e-05 23.0 1.6 4.7e-05 23.0 1.6 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OWF44883.1 - 4.8e-05 23.3 0.5 4.8e-05 23.3 0.5 2.9 1 1 1 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF44883.1 - 0.0014 18.5 6.5 0.0014 18.5 6.5 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF44883.1 - 0.0031 17.3 18.4 0.018 14.9 6.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OWF44883.1 - 0.0077 16.3 4.2 0.017 15.1 4.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Gemini_coat PF00844.18 OWF44883.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family GLTP PF08718.11 OWF44883.1 - 0.05 13.9 4.5 0.15 12.3 1.9 2.4 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) RRM_1 PF00076.22 OWF44883.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3H2C3 PF17122.5 OWF44883.1 - 0.26 11.3 6.1 0.84 9.7 6.1 2.0 1 1 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 OWF44883.1 - 2.8 7.9 20.5 0.59 10.0 6.3 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Helicase_C PF00271.31 OWF44884.1 - 0.00013 22.2 0.6 0.00031 21.1 0.6 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TPR_2 PF07719.17 OWF44884.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat LOR PF04525.12 OWF44884.1 - 0.059 13.0 1.0 0.17 11.5 1.0 1.7 1 0 0 1 1 1 0 LURP-one-related IF-2B PF01008.17 OWF44885.1 - 5.8e-77 258.7 0.4 6.6e-77 258.5 0.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 OWF44885.1 - 0.017 15.1 0.2 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 DeoR C terminal sensor domain Spb1_C PF07780.12 OWF44886.1 - 1.2e-59 201.5 33.0 1.2e-59 201.5 33.0 4.0 2 2 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OWF44886.1 - 1.1e-52 178.7 0.7 2.4e-52 177.6 0.2 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OWF44886.1 - 5.3e-44 149.9 15.9 5.3e-44 149.9 15.9 6.1 4 1 2 6 6 6 2 Domain of unknown function (DUF3381) 14-3-3 PF00244.20 OWF44887.1 - 6.6e-101 336.5 6.3 3.2e-50 170.7 0.3 2.0 2 0 0 2 2 2 2 14-3-3 protein FlaF PF07309.11 OWF44887.1 - 0.0016 18.5 0.2 0.56 10.2 0.0 2.5 2 0 0 2 2 2 2 Flagellar protein FlaF DUF4518 PF15008.6 OWF44887.1 - 0.0023 17.2 0.2 1.6 7.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4518) TPR_19 PF14559.6 OWF44887.1 - 0.052 14.1 2.7 2.6 8.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4010 PF13194.6 OWF44887.1 - 0.19 11.4 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) BRE1 PF08647.11 OWF44887.1 - 6.5 6.9 13.1 2.2 8.4 0.3 3.4 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase 14-3-3 PF00244.20 OWF44888.1 - 5.6e-97 323.6 5.9 6.4e-97 323.4 5.9 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 OWF44888.1 - 0.0069 16.4 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Flagellar protein FlaF CRISPR_Cse1 PF09481.10 OWF44888.1 - 0.054 12.6 0.7 0.085 11.9 0.7 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) CK2S PF15011.6 OWF44888.1 - 0.068 13.1 3.7 4.7 7.1 0.2 2.6 3 0 0 3 3 3 0 Casein Kinase 2 substrate VPS28 PF03997.12 OWF44888.1 - 0.076 12.7 2.5 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 VPS28 protein HEAT PF02985.22 OWF44889.1 - 1e-50 165.4 39.6 0.0041 17.2 0.0 25.5 28 0 0 28 28 25 11 HEAT repeat HEAT_EZ PF13513.6 OWF44889.1 - 1.7e-37 127.3 53.3 0.00019 21.8 0.1 23.8 22 5 5 27 27 27 8 HEAT-like repeat HEAT_2 PF13646.6 OWF44889.1 - 1.4e-34 118.3 41.1 0.00011 22.6 0.2 16.4 12 5 7 21 21 20 9 HEAT repeats Cnd1 PF12717.7 OWF44889.1 - 3.5e-22 79.2 1.9 0.028 14.5 0.0 12.1 8 3 0 10 10 10 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OWF44889.1 - 1.2e-17 64.2 2.0 0.00013 21.6 0.0 8.7 8 2 1 9 9 9 4 CLASP N terminal Adaptin_N PF01602.20 OWF44889.1 - 4.4e-15 55.2 9.4 4.1e-05 22.3 0.1 9.7 8 4 1 9 9 9 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OWF44889.1 - 1.3e-12 48.1 0.2 3.5 8.3 0.0 9.8 8 2 2 10 10 9 1 Vacuolar 14 Fab1-binding region UME PF08064.13 OWF44889.1 - 8.8e-09 35.2 7.8 0.021 14.8 0.0 10.2 11 1 1 12 12 11 1 UME (NUC010) domain ParcG PF10274.9 OWF44889.1 - 9.3e-09 35.7 10.0 0.0011 19.1 0.1 8.2 8 2 2 10 10 9 1 Parkin co-regulated protein DUF3385 PF11865.8 OWF44889.1 - 3.4e-07 30.3 4.1 0.15 12.0 0.0 8.9 6 2 0 8 8 8 1 Domain of unknown function (DUF3385) Dopey_N PF04118.14 OWF44889.1 - 0.00011 21.4 0.2 8.6 5.4 0.0 5.8 4 2 1 5 5 5 1 Dopey, N-terminal DUF937 PF06078.11 OWF44889.1 - 0.00067 20.3 10.6 2.7 8.6 0.1 6.5 6 1 1 7 7 7 1 Bacterial protein of unknown function (DUF937) Condensin2nSMC PF12422.8 OWF44889.1 - 0.01 16.0 0.1 0.33 11.1 0.0 3.6 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit BLM10_mid PF16507.5 OWF44889.1 - 0.017 13.8 1.1 1.3 7.6 0.1 3.6 4 0 0 4 4 4 0 Proteasome-substrate-size regulator, mid region Arteri_nucleo PF01481.16 OWF44889.1 - 0.091 13.1 0.5 0.22 11.8 0.5 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Arm PF00514.23 OWF44889.1 - 0.17 12.0 14.0 17 5.6 0.3 8.2 6 1 2 8 8 8 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 OWF44889.1 - 0.25 10.4 0.0 0.25 10.4 0.0 10.1 13 2 2 15 15 15 0 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 OWF44889.1 - 1.3 9.0 4.1 30 4.6 0.1 5.0 5 0 0 5 5 4 0 Domain of unknown function (DUF3437) RIX1 PF08167.12 OWF44889.1 - 3.2 7.5 17.8 2.3 7.9 0.1 7.3 8 0 0 8 8 7 0 rRNA processing/ribosome biogenesis Pkinase PF00069.25 OWF44890.1 - 6.4e-70 235.5 0.0 1e-69 234.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF44890.1 - 3.9e-35 121.4 0.0 5.2e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OWF44890.1 - 4.4e-10 40.1 2.8 1.2e-09 38.7 2.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OWF44890.1 - 1.3e-05 24.7 0.0 3.7e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OWF44890.1 - 0.0014 18.3 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OWF44890.1 - 0.0097 14.7 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF44890.1 - 0.02 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF44890.1 - 0.029 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OWF44890.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 zf-C3HC4_3 PF13920.6 OWF44891.1 - 1.1e-10 41.2 5.6 1.6e-10 40.7 5.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF44891.1 - 3.8e-10 39.5 8.2 5.1e-10 39.1 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF44891.1 - 7.2e-10 39.0 10.3 9.6e-10 38.6 10.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF44891.1 - 8.9e-09 35.1 10.8 1.3e-08 34.5 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF44891.1 - 3.1e-08 33.5 7.7 1.7e-07 31.2 8.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF44891.1 - 2.6e-07 30.5 6.9 3.7e-07 30.0 6.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF44891.1 - 4.9e-07 29.5 6.5 6.8e-07 29.0 6.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OWF44891.1 - 4.1e-06 26.9 8.5 5.9e-06 26.3 8.5 1.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OWF44891.1 - 1.8e-05 24.9 7.8 3.3e-05 24.1 7.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OWF44891.1 - 9.6e-05 22.4 3.9 0.00015 21.8 3.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 OWF44891.1 - 0.00027 20.9 2.1 0.00042 20.3 2.1 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 OWF44891.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_6 PF14835.6 OWF44891.1 - 0.013 15.3 2.2 0.024 14.5 2.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OWF44891.1 - 0.075 12.8 7.4 0.17 11.7 7.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OWF44891.1 - 0.079 12.6 5.2 0.13 11.9 5.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 OWF44891.1 - 0.19 11.9 2.1 0.41 10.8 2.1 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger RecR PF02132.15 OWF44891.1 - 0.29 10.7 2.0 0.63 9.7 0.2 2.1 2 0 0 2 2 2 0 RecR protein IBR PF01485.21 OWF44891.1 - 0.42 10.9 8.2 0.51 10.6 3.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain RINGv PF12906.7 OWF44891.1 - 0.8 9.9 6.4 3.2 8.0 6.4 1.9 1 1 0 1 1 1 0 RING-variant domain DUF3450 PF11932.8 OWF44892.1 - 0.0016 17.8 1.7 0.0016 17.8 1.7 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) PG_binding_4 PF12229.8 OWF44892.1 - 0.019 15.2 1.0 0.019 15.2 1.0 1.9 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TPR_MLP1_2 PF07926.12 OWF44892.1 - 0.035 14.2 2.5 0.035 14.2 2.5 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein H-kinase_dim PF02895.14 OWF44892.1 - 0.048 14.1 7.6 2 8.8 0.1 3.1 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DivIC PF04977.15 OWF44892.1 - 0.051 13.3 1.0 0.051 13.3 1.0 4.6 2 1 3 5 5 5 0 Septum formation initiator TolA_bind_tri PF16331.5 OWF44892.1 - 0.064 13.3 17.1 0.045 13.8 2.7 3.7 3 2 1 4 4 4 0 TolA binding protein trimerisation Tropomyosin_1 PF12718.7 OWF44892.1 - 0.23 11.6 39.5 0.67 10.1 8.8 3.6 1 1 2 3 3 3 0 Tropomyosin like TACC_C PF05010.14 OWF44892.1 - 0.51 10.1 34.8 0.083 12.7 22.3 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 OWF44892.1 - 0.78 9.8 34.0 0.043 13.9 7.2 3.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PhoU PF01895.19 OWF44892.1 - 0.86 10.1 7.2 9.1 6.8 0.0 4.1 1 1 2 3 3 3 0 PhoU domain Baculo_PEP_C PF04513.12 OWF44892.1 - 0.88 9.6 10.9 0.73 9.9 1.1 3.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.11 OWF44892.1 - 1.5 7.6 33.2 8.3 5.1 28.1 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 OWF44892.1 - 1.8 9.0 32.7 1.3 9.4 8.8 2.2 1 1 1 2 2 2 0 Fez1 Hrs_helical PF12210.8 OWF44892.1 - 2.7 8.6 13.9 0.32 11.6 5.7 3.3 1 1 3 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TSC22 PF01166.18 OWF44892.1 - 2.9 8.3 17.7 3.2 8.1 0.0 5.0 3 2 1 4 4 4 0 TSC-22/dip/bun family Spc7 PF08317.11 OWF44892.1 - 5.3 5.8 34.4 0.7 8.7 18.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 OWF44892.1 - 6.3 7.5 17.0 10 6.8 2.6 5.1 1 1 3 4 4 4 0 SlyX Yuri_gagarin PF15934.5 OWF44892.1 - 8 6.2 28.5 0.73 9.6 19.8 2.6 1 1 1 2 2 2 0 Yuri gagarin MADF_DNA_bdg PF10545.9 OWF44892.1 - 8.3 6.8 17.7 0.093 13.1 0.9 3.4 2 2 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF647 PF04884.14 OWF44893.1 - 3.6e-97 324.7 1.8 4.8e-97 324.3 1.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis CitMHS PF03600.16 OWF44893.1 - 0.011 15.0 3.7 0.013 14.7 0.2 2.0 2 0 0 2 2 2 0 Citrate transporter Pkinase_Tyr PF07714.17 OWF44894.1 - 5.6e-48 163.5 0.0 8.1e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_KSR1 PF13543.6 OWF44894.1 - 6.9e-41 139.4 2.1 1.2e-40 138.6 2.1 1.4 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Pkinase PF00069.25 OWF44894.1 - 9.5e-39 133.3 0.0 1.5e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 OWF44894.1 - 8.6e-07 28.8 8.2 1.5e-06 28.0 8.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 OWF44894.1 - 0.00024 20.5 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Oscp1 PF10188.9 OWF44894.1 - 0.081 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Organic solute transport protein 1 C1_2 PF03107.16 OWF44894.1 - 5.5 7.4 11.2 2.9 8.3 8.1 2.1 2 0 0 2 2 2 0 C1 domain Rep_fac_C PF08542.11 OWF44895.1 - 2.1e-23 82.5 0.1 1.4e-21 76.7 0.0 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 OWF44895.1 - 2e-17 63.8 0.0 4.6e-17 62.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OWF44895.1 - 2.8e-14 53.2 0.0 5.4e-10 39.3 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OWF44895.1 - 1.1e-08 35.2 0.0 1e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 OWF44895.1 - 1.3e-05 25.1 0.0 0.00033 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF44895.1 - 8.3e-05 23.0 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OWF44895.1 - 9.1e-05 22.2 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OWF44895.1 - 0.0001 22.6 0.2 0.11 12.7 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 OWF44895.1 - 0.00015 21.7 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OWF44895.1 - 0.00083 18.6 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 OWF44895.1 - 0.00097 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 OWF44895.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OWF44895.1 - 0.0011 19.0 0.0 0.14 12.2 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OWF44895.1 - 0.0012 18.3 0.1 0.16 11.4 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein DEAD PF00270.29 OWF44895.1 - 0.0023 17.7 0.2 0.04 13.7 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 OWF44895.1 - 0.0032 17.0 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 OWF44895.1 - 0.0036 16.7 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 OWF44895.1 - 0.0048 17.2 0.1 0.17 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 OWF44895.1 - 0.0054 16.8 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OWF44895.1 - 0.012 15.3 0.1 0.074 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 OWF44895.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OWF44895.1 - 0.019 14.3 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.23 OWF44895.1 - 0.036 12.8 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain TBP PF00352.21 OWF44895.1 - 0.11 12.5 0.0 0.42 10.6 0.0 2.0 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) AAA_3 PF07726.11 OWF44895.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin_6 PF13848.6 OWF44895.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain zf-H2C2_5 PF13909.6 OWF44896.1 - 6.4e-21 73.8 167.8 0.00058 19.5 0.4 22.1 21 1 0 21 21 21 14 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OWF44896.1 - 0.0044 17.4 0.6 0.0044 17.4 0.6 28.8 34 0 0 34 34 34 6 Zinc-finger double domain Ribosomal_S27e PF01667.17 OWF44896.1 - 6.9 6.5 7.5 3.3 7.5 1.0 4.2 3 0 0 3 3 3 0 Ribosomal protein S27 Rhodanese PF00581.20 OWF44897.1 - 4.4e-35 120.4 0.0 8.8e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain PhnA_Zn_Ribbon PF08274.12 OWF44898.1 - 0.067 13.2 0.2 0.067 13.2 0.2 3.3 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zf_C2H2_ZHX PF18387.1 OWF44898.1 - 0.3 10.8 27.1 0.13 11.9 1.1 5.3 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain Vault PF01505.18 OWF44899.1 - 8.7e-60 198.6 6.9 1.2e-17 63.8 0.2 5.3 6 0 0 6 6 6 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 OWF44899.1 - 4.3e-54 181.6 1.3 8.5e-54 180.6 1.3 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 OWF44899.1 - 1e-36 124.8 2.0 4.6e-34 116.3 0.0 4.0 3 1 0 3 3 3 1 Major Vault Protein Repeat domain Vault_2 PF17794.1 OWF44899.1 - 1e-34 118.7 0.0 1.7e-22 79.5 0.1 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 OWF44899.1 - 1.5e-30 105.0 0.0 3.4e-29 100.7 0.0 3.1 3 0 0 3 3 3 1 Major Vault Protein repeat domain B3_4 PF03483.17 OWF44899.1 - 0.013 15.2 0.3 0.057 13.1 0.0 2.2 2 0 0 2 2 2 0 B3/4 domain NfeD PF01957.18 OWF44899.1 - 0.21 12.0 3.1 24 5.4 0.1 3.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding zf-C3HC4_3 PF13920.6 OWF44900.1 - 2e-11 43.6 11.8 2e-11 43.6 11.8 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 OWF44900.1 - 8.2e-08 32.3 13.3 8.2e-08 32.3 13.3 2.9 2 1 0 2 2 1 1 FYVE zinc finger Armet PF10208.9 OWF44900.1 - 5.9e-05 23.0 12.7 0.011 15.6 1.0 3.1 3 1 0 3 3 3 2 Degradation arginine-rich protein for mis-folding HeH PF12949.7 OWF44900.1 - 6.3e-05 22.6 0.1 0.069 12.9 0.0 2.4 2 0 0 2 2 2 2 HeH/LEM domain SAP PF02037.27 OWF44900.1 - 0.00084 19.0 4.7 0.061 13.1 0.4 3.4 3 0 0 3 3 3 1 SAP domain DUF4518 PF15008.6 OWF44900.1 - 0.00096 18.4 1.4 0.11 11.7 0.1 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4518) Prok-RING_4 PF14447.6 OWF44900.1 - 0.0012 18.6 10.9 0.0012 18.6 10.9 2.6 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF44900.1 - 0.0049 17.2 31.8 0.02 15.2 12.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OWF44900.1 - 0.023 14.6 12.6 0.023 14.6 12.6 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF44900.1 - 0.083 12.8 32.4 0.05 13.5 12.1 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF44900.1 - 2.1 8.6 23.9 0.89 9.8 4.4 3.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Lyase_1 PF00206.20 OWF44901.1 - 4e-99 331.9 0.0 1.3e-98 330.2 0.0 1.7 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 OWF44901.1 - 1.2e-22 80.4 0.0 2.6e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Glyco_hydro_18 PF00704.28 OWF44902.1 - 2.6e-77 260.6 2.1 3.1e-77 260.4 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_10 PF00331.20 OWF44903.1 - 3.8e-43 147.9 2.7 5.7e-43 147.3 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 OWF44903.1 - 4.1e-12 46.5 0.6 2e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 OWF44903.1 - 0.00075 19.1 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PP2 PF14299.6 OWF44903.1 - 0.0095 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Phloem protein 2 CDC48_N PF02359.18 OWF44903.1 - 0.15 12.3 0.0 0.98 9.6 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain AAT PF03417.16 OWF44904.1 - 2e-31 109.4 0.0 3e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Stap_Strp_tox_C PF02876.17 OWF44904.1 - 0.097 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain EGF PF00008.27 OWF44906.1 - 1.1e-78 258.9 258.3 2.5e-07 30.9 5.1 16.7 16 1 0 16 16 16 15 EGF-like domain hEGF PF12661.7 OWF44906.1 - 2.1e-29 101.1 198.1 0.00013 22.4 7.1 17.4 16 1 0 16 16 16 13 Human growth factor-like EGF EGF_2 PF07974.13 OWF44906.1 - 7.2e-05 23.1 271.2 0.0014 18.9 12.5 15.8 16 0 0 16 16 16 12 EGF-like domain cEGF PF12662.7 OWF44906.1 - 0.0093 15.9 2.8 0.0093 15.9 2.8 15.2 15 2 0 15 15 15 4 Complement Clr-like EGF-like nos_propeller_2 PF18793.1 OWF44906.1 - 0.011 16.0 0.1 20 5.6 0.0 4.9 6 0 0 6 6 6 0 Nitrous oxide reductase propeller repeat 2 Nuc_N PF14448.6 OWF44906.1 - 0.029 14.2 0.1 45 4.0 0.0 4.2 4 0 0 4 4 4 0 Nuclease N terminal Sugar_tr PF00083.24 OWF44907.1 - 6.6e-31 107.6 16.4 6.6e-31 107.6 16.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF44907.1 - 4.7e-23 81.7 33.2 1e-15 57.5 12.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF44908.1 - 9.7e-30 103.8 18.2 1.3e-29 103.4 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF44908.1 - 4.9e-19 68.5 40.5 6.1e-12 45.1 14.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily PsaX PF08078.12 OWF44908.1 - 1.9 8.5 5.3 1.6 8.8 0.2 2.9 3 0 0 3 3 3 0 PsaX family Metallophos PF00149.28 OWF44909.1 - 0.0003 21.4 0.6 3.5 8.1 0.0 3.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Gp138_N PF18352.1 OWF44909.1 - 0.00082 19.4 0.4 1.3 9.1 0.0 3.0 1 1 2 3 3 3 2 Phage protein Gp138 N-terminal domain LppA PF16708.5 OWF44909.1 - 0.012 15.6 0.9 0.71 9.8 0.1 3.3 1 1 4 5 5 5 0 Lipoprotein confined to pathogenic Mycobacterium DUF4221 PF13970.6 OWF44909.1 - 0.013 15.1 3.9 0.05 13.2 3.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) MH2 PF03166.14 OWF44909.1 - 0.062 13.5 0.1 5.8 7.1 0.1 3.2 1 1 0 1 1 1 0 MH2 domain NPL PF17800.1 OWF44909.1 - 0.22 12.1 3.9 1.4e+02 3.1 0.5 4.2 2 1 2 5 5 5 0 Nucleoplasmin-like domain Ribosomal_L34e PF01199.18 OWF44909.1 - 0.3 11.4 1.4 23 5.4 0.9 2.7 1 1 1 2 2 2 0 Ribosomal protein L34e DUF5114 PF17141.4 OWF44909.1 - 0.65 10.6 4.2 2.3 8.8 1.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5114) adh_short PF00106.25 OWF44910.1 - 4.1e-25 88.4 0.0 6.4e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF44910.1 - 1.3e-18 67.4 0.0 2.2e-18 66.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF44910.1 - 6.3e-08 32.7 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OWF44910.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 OWF44910.1 - 0.028 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HTH_Tnp_IS1 PF12759.7 OWF44910.1 - 0.069 12.8 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 InsA C-terminal domain Tctex-1 PF03645.13 OWF44911.1 - 1.1e-24 86.7 0.0 2.5e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Tctex-1 family Phage_term_smal PF05944.12 OWF44911.1 - 0.065 13.2 0.5 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Phage small terminase subunit DUF445 PF04286.12 OWF44911.1 - 0.4 10.4 4.6 0.96 9.2 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) IL17 PF06083.11 OWF44912.1 - 7.8e-17 61.5 4.0 1.3e-16 60.9 4.0 1.3 1 0 0 1 1 1 1 Interleukin-17 Anemone_cytotox PF06369.12 OWF44913.1 - 0.00022 20.9 1.9 0.00023 20.8 1.9 1.1 1 0 0 1 1 1 1 Sea anemone cytotoxic protein Glyco_transf_6 PF03414.13 OWF44913.1 - 0.031 13.1 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 Galactosyl_T PF01762.21 OWF44914.1 - 3e-45 154.4 0.1 4.1e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF44914.1 - 0.0066 15.9 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DAO PF01266.24 OWF44915.1 - 1.9e-44 152.7 0.0 2.2e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF44915.1 - 0.00011 22.4 0.9 0.00098 19.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OWF44915.1 - 0.023 13.8 0.0 0.098 11.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A ACTH_domain PF00976.18 OWF44915.1 - 0.033 14.1 0.3 0.093 12.7 0.3 1.7 1 0 0 1 1 1 0 Corticotropin ACTH domain Pyr_redox_2 PF07992.14 OWF44915.1 - 0.037 13.2 0.1 0.65 9.2 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF44915.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 OWF44915.1 - 0.048 13.0 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OWF44915.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OWF44915.1 - 0.16 10.7 0.0 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OWF44915.1 - 0.2 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 OWF44916.1 - 5.2e-43 148.0 0.0 5.8e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF44916.1 - 0.00012 22.2 0.9 0.001 19.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OWF44916.1 - 0.015 14.4 0.0 0.079 12.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OWF44916.1 - 0.04 13.0 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 OWF44916.1 - 0.046 13.1 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OWF44916.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 OWF44916.1 - 0.19 10.9 0.2 0.93 8.7 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF44916.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Gal-3-0_sulfotr PF06990.11 OWF44917.1 - 1.1e-54 185.8 0.0 1.8e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase F-box-like PF12937.7 OWF44918.1 - 1.6e-07 31.1 0.3 3.9e-07 29.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF44918.1 - 7.6e-05 22.5 0.1 0.00016 21.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain SKA2 PF16740.5 OWF44919.1 - 4.9e-24 84.2 5.1 2.7e-23 81.8 5.1 2.0 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF3161 PF11362.8 OWF44919.1 - 1e-14 54.3 0.0 1.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) SKA1 PF07160.12 OWF44919.1 - 7.8e-05 22.6 2.0 0.0002 21.3 1.2 1.9 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF573 PF04504.14 OWF44919.1 - 0.062 14.0 0.3 0.18 12.5 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Syntaxin_2 PF14523.6 OWF44919.1 - 0.087 13.2 4.0 0.17 12.3 4.0 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DUF3164 PF11363.8 OWF44919.1 - 0.091 12.4 0.5 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) Tup_N PF08581.10 OWF44919.1 - 0.21 11.9 4.9 1.3 9.4 1.2 2.8 3 0 0 3 3 3 0 Tup N-terminal CAP_N PF01213.19 OWF44920.1 - 0.032 13.7 8.3 0.022 14.3 6.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal zf_C2H2_13 PF18508.1 OWF44920.1 - 0.078 12.6 0.3 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Zinc finger domain HSBP1 PF06825.12 OWF44920.1 - 0.18 11.7 0.8 0.38 10.6 0.8 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SPX PF03105.19 OWF44920.1 - 0.39 10.6 0.1 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 SPX domain zf-RING_2 PF13639.6 OWF44921.1 - 5.2e-14 52.3 6.1 1.1e-13 51.2 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF44921.1 - 2.8e-11 43.0 3.8 4.3e-11 42.3 2.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OWF44921.1 - 6.7e-10 38.7 4.9 1.4e-09 37.6 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF44921.1 - 8.8e-10 38.3 6.5 1.8e-09 37.2 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF44921.1 - 4.9e-08 33.1 7.0 1.6e-07 31.5 7.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF44921.1 - 6e-07 29.3 3.5 1.1e-06 28.5 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF44921.1 - 6.1e-07 29.4 4.9 1.3e-06 28.3 4.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ZNRF_3_ecto PF18212.1 OWF44921.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-C3HC4_3 PF13920.6 OWF44921.1 - 1.5e-05 24.7 3.4 2.8e-05 23.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44921.1 - 8.4e-05 22.4 4.0 0.00022 21.0 4.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OWF44921.1 - 0.0059 16.7 5.5 0.014 15.6 5.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OWF44921.1 - 0.012 15.7 4.5 0.19 11.8 4.6 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dak1_2 PF13684.6 OWF44921.1 - 0.046 12.8 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family FANCL_C PF11793.8 OWF44921.1 - 0.13 12.5 3.3 0.49 10.6 3.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 OWF44921.1 - 0.32 11.1 2.2 0.8 9.9 2.2 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 OWF44921.1 - 0.47 10.4 3.2 1.1 9.3 3.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 OWF44921.1 - 0.6 10.2 9.1 0.091 12.8 2.2 2.8 4 0 0 4 4 2 0 Zinc-finger Zn_ribbon_17 PF17120.5 OWF44921.1 - 0.83 9.3 4.0 2.3 7.9 4.0 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OWF44921.1 - 4.6 7.5 8.4 14 5.9 5.9 2.4 1 1 1 2 2 2 0 RING-variant domain Endonuc-dimeris PF09124.10 OWF44922.1 - 6.8 6.9 8.8 1.8 8.8 0.5 3.5 1 1 3 4 4 4 0 T4 recombination endonuclease VII, dimerisation CBM_14 PF01607.24 OWF44924.1 - 7.8e-19 67.6 31.7 4.3e-09 36.4 1.7 4.6 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain Laminin_G_3 PF13385.6 OWF44924.1 - 2.6e-05 24.4 0.0 4.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OWF44924.1 - 0.0027 18.3 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 OWF44925.1 - 0.00016 21.9 0.0 0.00034 20.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Adeno_shaft PF00608.17 OWF44925.1 - 0.1 12.5 0.0 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) CBM_14 PF01607.24 OWF44926.1 - 1.2e-05 25.3 2.0 0.022 14.9 0.2 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Laminin_G_3 PF13385.6 OWF44926.1 - 0.0061 16.7 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CBM_14 PF01607.24 OWF44927.1 - 0.0025 17.9 6.9 0.0025 17.9 6.9 3.5 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain DUF5081 PF16887.5 OWF44927.1 - 0.12 11.4 1.1 0.24 10.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) SH3_4 PF06347.13 OWF44928.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain zf-FCS PF06467.14 OWF44928.1 - 0.25 11.3 0.4 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HEAT_2 PF13646.6 OWF44930.1 - 9.3e-20 70.8 0.9 1.1e-09 38.6 0.4 2.6 1 1 1 2 2 2 2 HEAT repeats TIR_2 PF13676.6 OWF44930.1 - 1e-19 71.3 0.1 2.2e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 TIR domain HEAT PF02985.22 OWF44930.1 - 4.4e-07 29.6 0.6 0.02 15.1 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_PBS PF03130.16 OWF44930.1 - 8.4e-05 22.9 2.1 1.2 10.0 0.0 4.0 5 0 0 5 5 5 2 PBS lyase HEAT-like repeat Cbl_N2 PF02761.14 OWF44930.1 - 0.00016 22.3 1.7 0.00076 20.1 1.7 2.2 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Cnd1 PF12717.7 OWF44930.1 - 0.0011 19.1 0.4 0.0031 17.6 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OWF44930.1 - 0.002 18.6 3.8 0.086 13.4 0.1 4.1 3 1 0 4 4 4 1 HEAT-like repeat ERAP1_C PF11838.8 OWF44930.1 - 0.023 14.2 0.0 0.057 13.0 0.0 1.6 1 1 0 1 1 1 0 ERAP1-like C-terminal domain TIR PF01582.20 OWF44930.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.5 1 1 1 2 2 2 0 TIR domain DUF1863 PF08937.11 OWF44930.1 - 0.074 13.4 0.0 1.8 8.9 0.0 2.7 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) SMAP PF15477.6 OWF44931.1 - 4.5e-15 56.4 5.5 4.5e-15 56.4 5.5 3.3 3 1 0 3 3 3 1 Small acidic protein family Tctex-1 PF03645.13 OWF44932.1 - 6.7e-26 90.5 0.2 1.2e-25 89.7 0.2 1.4 1 0 0 1 1 1 1 Tctex-1 family FAM150 PF15129.6 OWF44932.1 - 0.16 12.2 0.9 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 FAM150 family IL17 PF06083.11 OWF44933.1 - 2.2e-17 63.3 0.3 3e-17 62.8 0.3 1.2 1 0 0 1 1 1 1 Interleukin-17 Death PF00531.22 OWF44934.1 - 0.035 14.3 0.4 1 9.6 0.0 3.1 2 0 0 2 2 2 0 Death domain NIL PF09383.10 OWF44934.1 - 0.16 11.8 0.3 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 NIL domain IL17 PF06083.11 OWF44935.1 - 2.2e-17 63.3 7.7 1.6e-16 60.5 1.5 2.8 3 0 0 3 3 3 2 Interleukin-17 IL17 PF06083.11 OWF44936.1 - 1e-10 41.9 0.9 3.3e-10 40.3 0.9 1.9 1 0 0 1 1 1 1 Interleukin-17 PAN_1 PF00024.26 OWF44937.1 - 1.4e-05 25.0 0.0 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PAN domain Lectin_C PF00059.21 OWF44937.1 - 0.00041 21.0 0.1 0.0019 18.9 0.0 1.9 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 OWF44937.1 - 0.0013 18.4 0.2 0.0026 17.4 0.2 1.5 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like PAN_4 PF14295.6 OWF44937.1 - 0.012 15.5 0.2 0.037 13.9 0.2 1.8 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 OWF44937.1 - 0.014 15.5 0.5 0.036 14.2 0.1 1.8 2 0 0 2 2 2 0 PAN-like domain Lectin_C PF00059.21 OWF44938.1 - 5.8e-11 43.1 0.0 6.5e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Lectin C-type domain Neur_chan_LBD PF02931.23 OWF44939.1 - 2.1e-32 112.3 0.5 4.1e-32 111.4 0.0 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44939.1 - 2.4e-16 60.5 11.1 3e-15 56.9 6.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 OWF44939.1 - 0.016 14.2 0.4 0.023 13.7 0.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Orf78 PF06024.12 OWF44939.1 - 0.017 15.4 0.2 0.017 15.4 0.2 2.7 2 1 0 3 3 3 0 Orf78 (ac78) VGCC_beta4Aa_N PF12052.8 OWF44939.1 - 0.056 13.6 0.8 0.11 12.7 0.8 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF2417 PF10329.9 OWF44939.1 - 7.8 5.8 13.8 34 3.7 9.9 2.6 2 1 0 2 2 2 0 Region of unknown function (DUF2417) DUF2207 PF09972.9 OWF44939.1 - 8.4 5.0 8.3 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) LRR_8 PF13855.6 OWF44940.1 - 1.2e-18 66.6 23.8 1.6e-08 34.2 9.2 4.3 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OWF44940.1 - 1.1e-15 57.5 27.6 1.5e-06 28.4 2.2 4.8 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) B3_4 PF03483.17 OWF44940.1 - 5.4e-10 39.2 0.1 8e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 B3/4 domain LRR_9 PF14580.6 OWF44940.1 - 9.5e-05 22.0 6.3 0.052 13.1 0.2 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OWF44940.1 - 0.00013 22.0 12.6 44 5.2 0.1 6.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF44940.1 - 0.23 11.6 31.0 1.1 9.4 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich repeat UNC-93 PF05978.16 OWF44941.1 - 2.4e-10 40.4 2.5 2.4e-10 40.4 2.5 2.5 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 RINGv PF12906.7 OWF44942.1 - 8.3e-15 54.6 13.8 3e-14 52.8 13.8 2.0 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OWF44942.1 - 0.021 15.2 12.7 0.021 15.2 12.7 2.5 3 0 0 3 3 3 0 Ring finger domain DevR PF01905.16 OWF44942.1 - 0.13 11.3 0.0 7.6 5.5 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated negative auto-regulator DevR/Csa2 zf-UDP PF14569.6 OWF44942.1 - 1.3 9.2 7.9 0.19 11.9 3.7 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger WD40 PF00400.32 OWF44943.1 - 3.8e-49 163.6 24.9 3.7e-08 33.9 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF44943.1 - 1.4e-09 38.1 0.4 0.034 14.5 0.0 4.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF44943.1 - 0.00015 21.7 0.7 0.0037 17.2 0.1 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF44943.1 - 0.00064 18.8 0.1 1.9 7.4 0.0 3.4 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OWF44943.1 - 0.0036 16.7 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain PD40 PF07676.12 OWF44943.1 - 0.013 15.5 0.1 11 6.1 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OWF44943.1 - 0.018 13.7 7.4 0.11 11.1 0.1 4.1 2 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF1416 PF07210.12 OWF44943.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Metallophos PF00149.28 OWF44944.1 - 2.4e-34 119.7 0.4 4.2e-34 118.9 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OWF44944.1 - 0.0029 18.0 0.3 0.0063 16.9 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 OWF44944.1 - 0.046 13.0 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) 23S_rRNA_IVP PF05635.11 OWF44944.1 - 0.14 12.4 0.6 0.33 11.3 0.5 1.6 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein SKA2 PF16740.5 OWF44945.1 - 0.085 12.7 5.6 0.085 12.6 0.4 3.5 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Lipoprotein_8 PF02030.15 OWF44947.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Neur_chan_LBD PF02931.23 OWF44948.1 - 6.8e-41 140.1 1.3 6.8e-41 140.1 1.3 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44948.1 - 1.5e-12 48.1 14.3 2e-11 44.4 8.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF44949.1 - 8.8e-38 129.9 0.1 1.3e-37 129.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44949.1 - 1.2e-09 38.6 1.1 1.8e-09 38.0 1.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF44950.1 - 1.6e-43 148.7 1.7 2.1e-43 148.3 1.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44950.1 - 1.9e-08 34.7 3.1 1.9e-08 34.7 3.1 1.6 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF44951.1 - 2e-33 115.7 0.3 2.8e-33 115.2 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF44951.1 - 1.5e-06 28.4 3.8 1.5e-06 28.4 3.8 2.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region GWT1 PF06423.12 OWF44951.1 - 0.16 12.1 2.8 0.5 10.5 2.0 2.1 1 1 0 1 1 1 0 GWT1 Choline_kinase PF01633.20 OWF44953.1 - 7.5e-60 202.1 0.1 1.2e-59 201.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OWF44953.1 - 1.3e-11 44.9 0.0 1.7e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OWF44953.1 - 0.00065 19.1 1.0 0.0038 16.6 1.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OWF44953.1 - 0.0011 18.0 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF1967 PF09269.11 OWF44953.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DUF2114 PF09887.9 OWF44953.1 - 0.3 9.5 0.0 0.44 9.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Sulfotransfer_1 PF00685.27 OWF44954.1 - 1.9e-51 175.1 4.0 1.4e-49 169.0 4.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF44954.1 - 3e-07 31.1 0.1 1.1e-06 29.2 0.1 1.8 2 0 0 2 2 2 1 Sulfotransferase family Ank_4 PF13637.6 OWF44955.1 - 1.6e-16 60.4 0.0 1.6e-12 47.6 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF44955.1 - 3.1e-16 59.7 0.0 1.9e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF44955.1 - 3.6e-12 46.1 0.0 2.8e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OWF44955.1 - 3e-11 43.3 0.0 7.6e-07 29.3 0.0 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF44955.1 - 5.6e-11 41.7 0.0 4e-06 26.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Kdo PF06293.14 OWF44955.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_7 PF02796.15 OWF44955.1 - 0.22 11.6 0.3 7.1 6.8 0.0 3.0 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase Ribosomal_S9 PF00380.19 OWF44956.1 - 1.3e-32 112.9 0.1 1.5e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Thymidylat_synt PF00303.19 OWF44957.1 - 1.3e-117 391.7 0.0 1.5e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase N_BRCA1_IG PF16158.5 OWF44958.1 - 1.6e-31 109.1 0.3 2.6e-31 108.4 0.3 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 OWF44958.1 - 3.2e-09 36.5 0.0 6.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain A_deaminase PF00962.22 OWF44959.1 - 2.8e-21 76.2 0.0 4.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 OWF44959.1 - 3.8e-19 68.8 0.0 8.7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal UPF0444 PF15475.6 OWF44960.1 - 5.6e-09 36.2 5.3 1.3e-08 35.0 5.3 1.7 1 1 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 2-oxoacid_dh PF00198.23 OWF44961.1 - 7.7e-71 238.2 0.5 1.1e-70 237.7 0.5 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OWF44961.1 - 2.1e-16 59.5 1.3 5.8e-16 58.1 1.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OWF44961.1 - 5.9e-09 36.1 0.0 1.6e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain DUF1999 PF09390.10 OWF44961.1 - 0.035 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) DUF3614 PF12267.8 OWF44961.1 - 0.055 14.0 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) GRDP-like PF07173.12 OWF44962.1 - 5.5e-47 160.0 0.7 2.9e-36 125.2 0.5 2.4 1 1 1 2 2 2 2 Glycine-rich domain-containing protein-like ABC_tran PF00005.27 OWF44963.1 - 7.2e-35 120.5 0.0 6.6e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 OWF44963.1 - 8.1e-13 48.0 6.4 8.1e-13 48.0 6.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 OWF44963.1 - 4.4e-11 42.6 5.2 0.00039 19.9 0.4 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OWF44963.1 - 1.2e-09 38.4 1.8 0.13 12.0 1.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 OWF44963.1 - 2.4e-08 33.4 3.2 2.4e-08 33.4 3.2 3.5 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_16 PF13191.6 OWF44963.1 - 2.2e-05 24.9 0.0 0.059 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OWF44963.1 - 2.4e-05 24.3 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 OWF44963.1 - 4.2e-05 23.4 1.6 4.2e-05 23.4 1.6 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_10 PF13237.6 OWF44963.1 - 5.7e-05 23.1 8.3 0.0025 17.9 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_15 PF13175.6 OWF44963.1 - 5.8e-05 23.0 0.2 0.17 11.5 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 OWF44963.1 - 7.6e-05 23.2 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF44963.1 - 0.00016 22.0 0.0 0.032 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OWF44963.1 - 0.00033 20.6 0.2 0.061 13.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 OWF44963.1 - 0.00085 19.1 0.1 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OWF44963.1 - 0.0009 18.9 1.0 1.2 9.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_21 PF14697.6 OWF44963.1 - 0.0012 18.9 12.3 0.0039 17.3 12.3 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 OWF44963.1 - 0.0014 18.6 0.5 0.0014 18.6 0.5 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 OWF44963.1 - 0.0014 18.8 0.0 0.35 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OWF44963.1 - 0.0016 18.1 1.5 0.2 11.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.7 OWF44963.1 - 0.0027 18.3 1.3 0.0027 18.3 1.3 3.1 2 1 2 4 4 4 1 4Fe-4S dicluster domain TsaE PF02367.17 OWF44963.1 - 0.0038 17.2 0.1 0.05 13.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OWF44963.1 - 0.0044 16.6 0.0 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OWF44963.1 - 0.0071 16.7 0.2 2.6 8.5 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Rad17 PF03215.15 OWF44963.1 - 0.0095 15.9 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_16 PF13484.6 OWF44963.1 - 0.0095 16.8 0.3 0.0095 16.8 0.3 2.9 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Thymidylate_kin PF02223.17 OWF44963.1 - 0.011 15.4 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Fer4_9 PF13187.6 OWF44963.1 - 0.017 15.2 11.6 0.017 15.2 11.6 2.0 2 0 0 2 2 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 OWF44963.1 - 0.021 14.6 0.3 1.1 8.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 OWF44963.1 - 0.026 14.6 0.1 7.9 6.6 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_17 PF13534.6 OWF44963.1 - 0.031 14.8 0.2 0.031 14.8 0.2 2.6 2 0 0 2 2 1 0 4Fe-4S dicluster domain AAA_28 PF13521.6 OWF44963.1 - 0.044 14.0 0.7 11 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OWF44963.1 - 0.046 13.8 0.6 16 5.6 0.1 3.0 2 2 1 3 3 3 0 AAA domain NB-ARC PF00931.22 OWF44963.1 - 0.054 12.7 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 OWF44963.1 - 0.065 13.7 7.1 0.17 12.4 0.2 2.6 2 1 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 OWF44963.1 - 0.076 13.5 0.1 0.076 13.5 0.1 2.9 3 0 0 3 3 2 0 4Fe-4S dicluster domain VirE PF05272.11 OWF44963.1 - 0.077 12.7 0.0 5.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E MeaB PF03308.16 OWF44963.1 - 0.11 11.5 0.1 6.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OWF44963.1 - 0.15 12.6 0.0 7 7.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 OWF44963.1 - 0.19 11.7 1.0 2.7 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_4 PF12800.7 OWF44963.1 - 3.4 8.4 14.5 0.98 10.1 3.0 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Hexapep_2 PF14602.6 OWF44964.1 - 0.00059 19.5 99.8 13 5.6 0.0 34.6 41 1 0 41 41 41 5 Hexapeptide repeat of succinyl-transferase DUF4448 PF14610.6 OWF44965.1 - 0.0031 17.3 0.1 0.0082 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Cu2_monooxygen PF01082.20 OWF44966.1 - 9.2e-05 22.7 76.2 11 6.2 2.0 17.1 2 2 23 26 26 26 9 Copper type II ascorbate-dependent monooxygenase, N-terminal domain WD40_4 PF16300.5 OWF44966.1 - 0.00017 21.4 0.0 2e+02 2.0 0.0 8.6 7 2 2 9 9 9 0 Type of WD40 repeat PTS_EIIA_2 PF00359.22 OWF44966.1 - 0.0018 18.2 14.8 5.9 6.8 0.1 10.1 3 3 9 12 12 12 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SGTA_dimer PF16546.5 OWF44966.1 - 0.0041 16.9 0.8 1.7e+02 2.1 0.0 6.1 6 1 0 6 6 6 0 Homodimerisation domain of SGTA DUF3258 PF11646.8 OWF44966.1 - 1.3 9.2 30.6 99 3.2 1.1 10.6 2 2 6 9 9 9 0 Protein of unknown function DUF3258 EIIC-GAT PF03611.14 OWF44966.1 - 1.4 8.0 8.2 67 2.4 0.1 5.6 3 2 1 6 6 6 0 PTS system sugar-specific permease component Lipase_GDSL_2 PF13472.6 OWF44968.1 - 0.0045 17.4 0.0 0.011 16.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF44968.1 - 0.038 13.9 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase AAA_lid_3 PF17862.1 OWF44970.1 - 6.9e-08 32.2 0.6 1.8e-07 30.9 0.1 1.8 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 OWF44970.1 - 0.00081 19.8 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Hexapep_loop PF18776.1 OWF44971.1 - 0.0045 16.6 39.1 20 4.9 0.1 11.0 12 0 0 12 12 12 3 Hexapeptide repeat including loop SAM_2 PF07647.17 OWF44971.1 - 0.011 15.8 0.4 18 5.5 0.1 3.1 1 1 2 3 3 3 0 SAM domain (Sterile alpha motif) LysM PF01476.20 OWF44971.1 - 0.019 15.0 13.6 11 6.2 0.3 6.1 1 1 3 4 4 4 0 LysM domain Ribosomal_L4 PF00573.22 OWF44971.1 - 0.04 13.6 7.1 10 5.8 3.3 3.6 1 1 2 3 3 3 0 Ribosomal protein L4/L1 family CM_1 PF07736.11 OWF44971.1 - 0.079 13.4 19.0 0.77 10.2 3.9 3.5 1 1 2 3 3 3 0 Chorismate mutase type I Oest_recep PF02159.15 OWF44971.1 - 0.13 12.8 3.4 22 5.5 0.9 3.5 1 1 1 2 2 2 0 Oestrogen receptor DUF4518 PF15008.6 OWF44971.1 - 0.38 9.9 9.2 3.3 6.8 1.9 2.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4518) MMR_HSR1_Xtn PF16897.5 OWF44971.1 - 0.46 10.5 5.9 3.7 7.6 2.3 2.4 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain Stealth_CR1 PF17101.5 OWF44972.1 - 0.058 13.1 0.2 0.098 12.4 0.2 1.4 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 DUF3685 PF12452.8 OWF44972.1 - 0.092 12.4 0.6 0.11 12.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) CLN3 PF02487.17 OWF44972.1 - 0.18 10.8 0.3 0.2 10.7 0.3 1.0 1 0 0 1 1 1 0 CLN3 protein zf-C2H2 PF00096.26 OWF44973.1 - 8.7e-13 48.0 13.1 3.1e-06 27.3 1.8 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF44973.1 - 9.1e-10 38.5 10.0 7.5e-05 23.2 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OWF44973.1 - 1.4e-07 31.7 4.1 0.0048 17.3 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OWF44973.1 - 8.9e-05 22.7 15.3 0.00064 20.0 2.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 OWF44973.1 - 0.00012 22.4 3.3 0.16 12.3 0.2 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OWF44973.1 - 0.00012 22.2 9.4 0.068 13.5 1.0 2.7 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 OWF44973.1 - 0.0014 18.5 3.3 0.02 14.8 0.7 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 OWF44973.1 - 0.0047 16.5 2.2 0.25 11.0 0.2 2.4 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 OWF44973.1 - 0.0063 16.4 0.7 0.23 11.4 0.0 2.3 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-Di19 PF05605.12 OWF44973.1 - 0.0074 16.6 3.4 0.013 15.8 3.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 OWF44973.1 - 0.0077 16.1 1.6 2.9 7.9 0.1 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 DZR PF12773.7 OWF44973.1 - 0.012 15.6 1.7 0.018 15.0 1.7 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 OWF44973.1 - 0.017 15.0 4.3 0.1 12.5 0.4 2.2 2 0 0 2 2 2 0 HIT zinc finger DUF1272 PF06906.11 OWF44973.1 - 0.029 14.4 1.3 0.05 13.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Mut7-C PF01927.16 OWF44973.1 - 0.038 14.1 0.5 0.045 13.9 0.5 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain LIM PF00412.22 OWF44973.1 - 0.044 14.0 4.8 0.077 13.2 4.8 1.4 1 0 0 1 1 1 0 LIM domain Zn-C2H2_12 PF18112.1 OWF44973.1 - 0.063 13.8 2.4 1.4 9.5 0.5 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 OWF44973.1 - 0.076 12.9 1.1 2.5 8.0 0.0 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 OWF44973.1 - 0.081 13.1 2.7 0.21 11.7 2.6 1.7 1 1 0 1 1 1 0 Zinc ribbon domain HNH_5 PF14279.6 OWF44973.1 - 0.12 12.3 4.7 1 9.3 4.7 2.1 1 1 0 1 1 1 0 HNH endonuclease zf-C2H2_6 PF13912.6 OWF44973.1 - 0.17 11.9 10.4 1 9.5 0.3 2.8 3 1 0 3 3 2 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 OWF44973.1 - 0.19 12.0 1.9 0.84 10.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon zinc-ribbons_6 PF07191.12 OWF44973.1 - 0.2 11.6 3.2 0.81 9.7 3.4 1.7 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_5 PF13719.6 OWF44973.1 - 0.26 11.1 2.5 1.5 8.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2225 PF09986.9 OWF44973.1 - 0.33 10.6 3.7 2.1 8.0 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_4 PF13717.6 OWF44973.1 - 0.43 10.6 3.8 1.2 9.1 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain FOXP-CC PF16159.5 OWF44973.1 - 0.57 10.8 4.3 17 6.2 1.0 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain Prok-RING_4 PF14447.6 OWF44973.1 - 0.81 9.6 5.7 1.6 8.7 0.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-H2C2_5 PF13909.6 OWF44973.1 - 0.95 9.3 0.1 0.95 9.3 0.1 2.7 3 0 0 3 3 2 0 C2H2-type zinc-finger domain PEP-utilisers_N PF05524.13 OWF44974.1 - 0.023 14.9 0.2 0.029 14.5 0.2 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Complex1_LYR_2 PF13233.6 OWF44974.1 - 0.025 15.3 0.4 0.03 15.1 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like RcsC PF09456.10 OWF44974.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.4 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) DUF3060 PF11259.8 OWF44975.1 - 1.2e-06 28.1 0.0 0.1 12.3 0.0 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3060) Pam17 PF08566.10 OWF44975.1 - 0.34 10.7 0.7 5.6 6.8 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 Cementoin PF10511.9 OWF44975.1 - 2.1 8.8 0.1 2.1 8.8 0.1 6.7 9 0 0 9 9 9 0 Trappin protein transglutaminase binding domain DUF3060 PF11259.8 OWF44976.1 - 1.1e-14 53.9 3.2 0.003 17.2 0.1 4.9 1 1 4 5 5 5 5 Protein of unknown function (DUF3060) ThiP_synth PF10120.9 OWF44976.1 - 0.0052 16.4 10.1 36 3.9 0.1 6.2 4 2 4 8 8 8 2 Thiamine-phosphate synthase Flagellar_put PF12611.8 OWF44976.1 - 0.018 14.8 44.8 56 3.6 0.2 14.7 17 0 0 17 17 17 0 Putative flagellar RP-C_C PF11800.8 OWF44976.1 - 0.59 10.2 1.5 3e+02 1.4 0.0 3.9 4 0 0 4 4 4 0 Replication protein C C-terminal region Pam17 PF08566.10 OWF44976.1 - 0.89 9.4 8.1 7.1 6.5 0.1 3.6 1 1 4 5 5 5 0 Mitochondrial import protein Pam17 Flagellar_put PF12611.8 OWF44977.1 - 0.00039 20.1 7.7 18 5.2 0.1 6.1 7 0 0 7 7 7 3 Putative flagellar DUF4573 PF15140.6 OWF44977.1 - 0.0034 17.2 0.6 0.0038 17.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) DUF3060 PF11259.8 OWF44977.1 - 0.0054 16.4 0.1 0.0073 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3060) Cementoin PF10511.9 OWF44977.1 - 0.13 12.6 0.4 0.13 12.6 0.4 3.6 7 0 0 7 7 7 0 Trappin protein transglutaminase binding domain Regnase_1_C PF18561.1 OWF44977.1 - 1.7 8.4 9.3 45 3.9 0.1 4.5 2 2 3 5 5 5 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Glycos_transf_3 PF00591.21 OWF44978.1 - 1.7e-36 126.1 2.6 2.7e-36 125.5 2.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OWF44978.1 - 2.7e-16 59.2 0.2 5.7e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 OWF44978.1 - 5.3e-14 51.6 0.1 1.4e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain Biotin_lipoyl PF00364.22 OWF44978.1 - 0.031 14.1 0.9 12 5.9 0.0 3.0 2 0 0 2 2 2 0 Biotin-requiring enzyme Methyltransf_25 PF13649.6 OWF44979.1 - 2.3e-11 44.2 0.0 2.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF44979.1 - 6.5e-11 42.7 0.0 8e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF44979.1 - 2.8e-07 30.5 0.0 3.4e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44979.1 - 8.1e-05 22.1 0.0 9.3e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OWF44979.1 - 0.00011 22.9 0.0 0.00013 22.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OWF44979.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 OWF44980.1 - 5.4e-08 33.4 0.1 1.2e-07 32.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44980.1 - 4.1e-07 30.6 0.0 1.1e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44980.1 - 0.00035 21.3 0.0 0.0055 17.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44980.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OWF44980.1 - 0.0022 17.8 0.1 0.0029 17.4 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain CbiK PF06180.11 OWF44980.1 - 0.083 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Methyltransf_11 PF08241.12 OWF44981.1 - 1.6e-09 38.3 0.0 2.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF44981.1 - 3.6e-08 34.0 0.0 5.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF44981.1 - 9.5e-05 23.1 0.0 0.00038 21.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF44981.1 - 0.00014 21.7 0.1 0.00018 21.3 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF44981.1 - 0.00041 19.7 0.0 0.0013 18.1 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF44981.1 - 0.023 14.5 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain BIR PF00653.21 OWF44982.1 - 1.7e-31 108.6 11.4 4.9e-17 62.3 0.4 3.4 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF44982.1 - 5.2e-10 39.0 13.1 5.2e-10 39.0 13.1 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF44982.1 - 0.0031 17.3 12.6 0.0031 17.3 12.6 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 GPR15L PF15854.5 OWF44982.1 - 2.6 8.4 8.8 0.85 9.9 0.5 3.3 3 0 0 3 3 3 0 G-protein coupled receptor ligand 15 Sugar_tr PF00083.24 OWF44983.1 - 1.5e-32 113.1 27.5 4.1e-32 111.6 27.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF44983.1 - 1.4e-28 99.9 46.0 5.5e-25 88.0 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF44983.1 - 3.3 6.9 18.8 0.015 14.6 6.7 2.1 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB Astacin PF01400.24 OWF44984.1 - 3.9e-44 150.6 0.0 4.5e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OWF44984.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Matrixin Sugar_tr PF00083.24 OWF44985.1 - 7.6e-36 123.9 11.7 1.1e-35 123.4 11.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF44985.1 - 4.8e-21 75.1 23.9 8.4e-15 54.5 5.5 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily PIF PF05092.12 OWF44985.1 - 0.036 12.8 0.2 0.055 12.2 0.2 1.2 1 0 0 1 1 1 0 Per os infectivity Lipase_GDSL_2 PF13472.6 OWF44986.1 - 0.00064 20.2 0.0 0.00074 20.0 0.0 1.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sugar_tr PF00083.24 OWF44987.1 - 9.7e-29 100.5 19.5 1.4e-28 100.0 19.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF44987.1 - 1.2e-16 60.6 26.7 2.5e-16 59.5 26.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OWF44987.1 - 0.0029 16.9 3.4 0.0029 16.9 3.4 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sulfotransfer_2 PF03567.14 OWF44988.1 - 5.7e-31 108.3 4.8 8.9e-28 97.9 2.3 2.5 2 0 0 2 2 2 2 Sulfotransferase family Nexin_C PF08628.12 OWF44988.1 - 0.16 12.6 0.1 0.55 10.8 0.0 1.9 2 0 0 2 2 2 0 Sorting nexin C terminal fn3 PF00041.21 OWF44989.1 - 3.2e-46 155.6 39.4 1.4e-09 38.1 1.0 8.4 7 1 0 7 7 7 7 Fibronectin type III domain Reeler PF02014.16 OWF44989.1 - 1.9 9.3 6.9 15 6.4 0.1 4.8 5 0 0 5 5 5 0 Reeler domain DUF2369 PF10179.9 OWF44989.1 - 3.8 8.0 13.7 9.2 6.7 0.1 4.8 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) EB PF01683.18 OWF44990.1 - 4.3e-10 39.7 35.9 5.1e-05 23.5 8.1 3.3 1 1 2 3 3 3 3 EB module EGF_MSP1_1 PF12946.7 OWF44990.1 - 3.5 7.8 27.6 0.16 12.1 2.6 4.1 3 2 0 3 3 3 0 MSP1 EGF domain 1 CARD PF00619.21 OWF44991.1 - 1.1e-22 79.8 2.2 1.9e-16 59.8 0.3 2.7 2 0 0 2 2 2 2 Caspase recruitment domain CARD_2 PF16739.5 OWF44991.1 - 1.5e-06 28.1 0.4 1.1e-05 25.3 0.1 2.4 2 0 0 2 2 2 1 Caspase recruitment domain eIF2_C PF09173.11 OWF44992.1 - 8.3e-37 125.3 0.5 2.6e-36 123.8 0.5 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OWF44992.1 - 6.8e-23 81.2 0.2 5.9e-22 78.2 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OWF44992.1 - 1.4e-11 44.6 0.2 3.3e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OWF44992.1 - 0.00025 21.0 1.3 0.029 14.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF44992.1 - 0.0041 17.2 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OWF44992.1 - 0.0074 16.3 0.2 0.016 15.2 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Peptidase_M50 PF02163.22 OWF44993.1 - 4.6e-24 85.0 0.1 5.5e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M50 DUF1981 PF09324.10 OWF44996.1 - 9.1e-09 35.1 0.2 4.7e-07 29.6 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DCB PF16213.5 OWF44996.1 - 5.5e-08 32.7 2.1 1.7e-07 31.1 2.1 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 OWF44996.1 - 0.0014 18.5 0.0 0.012 15.5 0.0 2.7 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1281_C PF18406.1 OWF44996.1 - 0.17 11.6 0.0 0.48 10.2 0.0 1.7 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein SLC35F PF06027.12 OWF44997.1 - 5.4e-102 341.3 19.8 6.4e-102 341.1 19.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OWF44997.1 - 5.4e-15 55.8 23.4 8.6e-09 35.7 7.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 OWF44997.1 - 2.3e-08 33.4 1.2 2.3e-08 33.4 1.2 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 OWF44997.1 - 5.2e-06 25.9 16.5 8.1e-06 25.2 16.5 1.4 1 1 0 1 1 1 1 UAA transporter family Mg_trans_NIPA PF05653.14 OWF44997.1 - 0.001 18.3 1.0 0.001 18.3 1.0 2.5 1 1 1 2 2 2 1 Magnesium transporter NIPA HCV_core PF01542.18 OWF44997.1 - 0.4 11.1 4.5 3.7 8.0 0.0 3.3 3 0 0 3 3 3 0 Hepatitis C virus core protein YwiC PF14256.6 OWF44997.1 - 2.3 8.5 9.1 0.12 12.7 1.1 2.6 2 1 1 3 3 3 0 YwiC-like protein PWI PF01480.17 OWF44998.1 - 7.2e-27 93.5 0.0 1.6e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 PWI domain TauD PF02668.16 OWF45000.1 - 3.7e-36 125.3 0.0 5.1e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OWF45000.1 - 1.6e-20 73.5 2.1 4.1e-17 62.6 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.10 OWF45000.1 - 0.088 11.9 0.1 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 CsiD DUF2442 PF10387.9 OWF45000.1 - 0.095 13.0 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) TauD PF02668.16 OWF45001.1 - 6.8e-32 111.3 0.1 9.1e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OWF45001.1 - 1.6e-18 67.1 0.5 5.8e-18 65.3 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF971) NAD1 PF18778.1 OWF45001.1 - 0.042 13.9 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 HTH_29 PF13551.6 OWF45001.1 - 0.053 13.5 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Limkain-b1 PF11608.8 OWF45001.1 - 0.071 13.2 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 Imm40 PF15569.6 OWF45001.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 40 Ras PF00071.22 OWF45002.1 - 3.3e-57 192.6 0.0 3.9e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF45002.1 - 2e-35 121.6 0.0 3.6e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF45002.1 - 2.6e-13 49.8 0.0 3.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF45002.1 - 0.00014 21.9 0.1 0.02 14.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OWF45002.1 - 0.00048 19.6 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF45002.1 - 0.00052 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF45002.1 - 0.00066 19.3 0.0 0.0014 18.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OWF45002.1 - 0.012 15.3 0.1 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2093 PF09866.9 OWF45002.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) RabGAP-TBC PF00566.18 OWF45003.1 - 3.4e-49 167.4 8.4 5.3e-49 166.8 8.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OWF45003.1 - 7.3e-32 110.2 0.1 1.6e-31 109.1 0.1 1.6 1 0 0 1 1 1 1 Rab-binding domain (RBD) MRP-L47 PF06984.13 OWF45003.1 - 0.066 13.3 0.9 1 9.5 0.3 2.6 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Calcipressin PF04847.12 OWF45004.1 - 7.9e-43 146.4 0.5 1.3e-42 145.6 0.5 1.3 1 0 0 1 1 1 1 Calcipressin Cytochrom_C552 PF02335.15 OWF45004.1 - 0.006 15.6 0.0 0.0083 15.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c552 Barstar PF01337.18 OWF45004.1 - 0.13 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) WD40 PF00400.32 OWF45005.1 - 1.1e-13 51.4 11.8 0.0024 18.7 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 OWF45005.1 - 0.022 14.1 0.0 0.03 13.6 0.0 1.4 1 1 0 1 1 1 0 WD40-like domain Transmemb_17 PF09799.9 OWF45006.1 - 2.8e-33 114.7 12.8 3.9e-33 114.2 12.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein SNase PF00565.17 OWF45007.1 - 2.6e-64 214.5 1.0 5.5e-16 59.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OWF45007.1 - 5.1e-28 97.6 0.2 9.7e-28 96.6 0.2 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 OWF45007.1 - 0.0029 18.1 0.7 0.13 12.7 0.1 3.2 2 0 0 2 2 2 1 Agenet domain Sugar_tr PF00083.24 OWF45008.1 - 5.4e-28 98.1 21.4 7.7e-28 97.5 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF45008.1 - 1.1e-26 93.6 32.4 7.2e-16 58.0 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LOH1CR12 PF10158.9 OWF45009.1 - 1.2e-35 122.4 0.6 1.6e-35 122.0 0.6 1.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.12 OWF45009.1 - 0.033 14.2 0.4 0.046 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) 2OG-FeII_Oxy_2 PF13532.6 OWF45010.1 - 1e-29 104.1 0.1 1.3e-29 103.8 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 3HCDH_N PF02737.18 OWF45011.1 - 6.9e-42 143.4 0.0 1.4e-41 142.3 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OWF45011.1 - 1.2e-11 45.1 0.0 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OWF45011.1 - 1.8e-05 24.9 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 OWF45011.1 - 9.7e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OWF45011.1 - 0.00038 20.1 0.1 0.00075 19.1 0.1 1.5 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OWF45011.1 - 0.00097 19.1 0.0 0.0028 17.6 0.0 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 OWF45011.1 - 0.0048 16.2 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 OWF45011.1 - 0.047 13.0 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 OWF45011.1 - 0.05 13.2 0.2 0.085 12.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 OWF45011.1 - 0.054 13.7 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain IlvN PF07991.12 OWF45011.1 - 0.13 11.8 0.0 8.7 5.9 0.0 2.2 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 OWF45011.1 - 0.17 12.5 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OWF45012.1 - 1.6e-47 161.7 0.0 2.5e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OWF45012.1 - 2.4e-13 50.5 0.0 4.7e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.14 OWF45012.1 - 0.00033 20.0 0.0 0.0017 17.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OWF45012.1 - 0.0029 17.0 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OWF45012.1 - 0.0045 16.6 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OWF45012.1 - 0.0062 16.5 0.0 0.0093 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 OWF45012.1 - 0.0077 16.4 0.1 0.029 14.5 0.1 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 OWF45012.1 - 0.014 16.0 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OWF45012.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OWF45012.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KdpC PF02669.15 OWF45012.1 - 0.12 12.2 0.2 0.5 10.2 0.2 1.9 1 1 0 1 1 1 0 K+-transporting ATPase, c chain ThiF PF00899.21 OWF45012.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 OWF45012.1 - 0.18 12.3 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Bcl-2 PF00452.19 OWF45013.1 - 1e-05 26.1 0.0 2.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Vault PF01505.18 OWF45014.1 - 6.6e-50 167.0 0.6 3.3e-13 49.5 0.0 4.8 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 OWF45014.1 - 4.2e-45 152.6 0.0 8.6e-45 151.6 0.0 1.6 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 OWF45014.1 - 3.2e-38 129.6 0.2 1.1e-30 105.5 0.0 3.5 3 0 0 3 3 3 3 Major Vault Protein Repeat domain Vault_4 PF17796.1 OWF45014.1 - 5.7e-22 77.6 0.0 8.5e-21 73.8 0.1 2.6 3 0 0 3 3 3 1 Major Vault Protein repeat domain Vault_2 PF17794.1 OWF45014.1 - 6e-17 61.8 5.4 5.2e-09 36.4 1.2 3.2 2 1 0 2 2 2 2 Major Vault Protein repeat domain DUF2917 PF11142.8 OWF45015.1 - 1.5e-15 56.3 36.9 25 4.4 0.1 18.7 1 1 44 46 46 46 1 Protein of unknown function (DUF2917) DUF3992 PF13157.6 OWF45015.1 - 1.7e-08 35.1 69.2 6.6 7.5 2.1 13.4 1 1 4 5 5 5 3 Protein of unknown function (DUF3992) UL11 PF11094.8 OWF45015.1 - 1.2e-07 31.4 3.4 68 3.5 0.0 13.5 3 2 1 5 5 5 0 Membrane-associated tegument protein FLgD_tudor PF13861.6 OWF45015.1 - 0.0036 17.5 0.0 28 5.1 0.0 7.4 1 1 0 1 1 1 0 FlgD Tudor-like domain Ribosomal_S4e PF00900.20 OWF45015.1 - 0.0079 16.1 123.4 8.7 6.3 2.6 20.4 1 1 3 4 4 4 1 Ribosomal family S4e DUF4249 PF14054.6 OWF45015.1 - 0.0086 15.7 0.1 18 4.8 0.1 5.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4249) TOBE PF03459.17 OWF45015.1 - 0.059 13.7 34.7 1e+02 3.3 0.3 10.7 1 1 3 6 6 6 0 TOBE domain DUF1298 PF06974.13 OWF45016.1 - 2.1e-20 73.2 0.0 5.5e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 OWF45016.1 - 1.9e-11 44.3 0.0 7.9e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain zf-rbx1 PF12678.7 OWF45017.1 - 1.2e-06 28.7 1.2 2.7e-06 27.5 1.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain RWD PF05773.22 OWF45017.1 - 2.9e-06 27.5 0.8 5.9e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 RWD domain zf-C3HC4 PF00097.25 OWF45017.1 - 1.3e-05 24.9 2.6 4.1e-05 23.3 2.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF45017.1 - 0.00026 21.3 3.2 0.00026 21.3 3.2 2.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF45017.1 - 0.0053 16.8 2.0 0.016 15.2 2.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF45017.1 - 0.0078 16.2 3.1 0.027 14.4 3.1 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OWF45017.1 - 0.013 15.3 2.0 0.053 13.3 0.2 2.7 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 OWF45017.1 - 0.018 15.1 0.8 0.035 14.1 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OWF45017.1 - 0.019 14.8 1.1 0.019 14.8 1.1 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OWF45017.1 - 0.029 14.5 2.6 0.14 12.4 2.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OWF45017.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF45017.1 - 0.32 10.9 7.5 0.097 12.5 2.7 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 OWF45017.1 - 0.43 10.6 2.7 0.82 9.7 0.4 2.4 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-RING-like PF08746.11 OWF45017.1 - 1.5 9.2 4.3 0.39 11.0 0.4 2.0 2 0 0 2 2 2 0 RING-like domain DNA_pol3_a_NII PF11490.8 OWF45017.1 - 4.5 7.2 6.4 2.6 8.0 0.1 2.8 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus II Pkinase PF00069.25 OWF45018.1 - 5e-54 183.4 0.0 8.3e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF45018.1 - 3.5e-24 85.5 0.0 5.4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4148 PF13663.6 OWF45018.1 - 0.021 15.0 0.2 0.038 14.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) MRVI1 PF05781.12 OWF45019.1 - 8.3e-52 176.6 10.8 8.3e-52 176.6 10.8 3.9 2 1 2 4 4 4 1 MRVI1 protein EF-hand_9 PF14658.6 OWF45019.1 - 2.3e-14 53.5 0.9 5.9e-14 52.1 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain KASH_CCD PF14662.6 OWF45019.1 - 5.9e-14 52.3 42.7 5.9e-14 52.3 42.7 6.6 4 3 2 6 6 6 2 Coiled-coil region of CCDC155 or KASH zf-TRM13_CCCH PF11722.8 OWF45021.1 - 0.0015 18.2 5.7 29 4.5 0.1 6.2 5 1 2 7 7 7 4 CCCH zinc finger in TRM13 protein zf-TRM13_CCCH PF11722.8 OWF45022.1 - 0.00015 21.4 2.9 2.1 8.2 0.1 5.8 5 2 2 7 7 7 1 CCCH zinc finger in TRM13 protein DCR PF14047.6 OWF45022.1 - 0.18 12.1 7.4 23 5.3 0.2 4.1 1 1 2 3 3 3 0 Dppa2/4 conserved region PRNT PF15174.6 OWF45022.1 - 0.77 9.8 5.8 1.2 9.2 0.8 3.0 1 1 2 3 3 3 0 Prion-related protein testis-specific zf-TRM13_CCCH PF11722.8 OWF45023.1 - 0.00014 21.5 6.7 59 3.6 0.0 8.5 7 2 3 10 10 10 1 CCCH zinc finger in TRM13 protein DUF2671 PF10877.8 OWF45023.1 - 7.7 6.4 8.5 2 8.3 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2671) Sushi PF00084.20 OWF45025.1 - 1.5e-11 44.7 2.9 0.0001 22.8 0.3 3.0 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) SKG6 PF08693.10 OWF45025.1 - 0.0044 16.4 0.8 0.0044 16.4 0.8 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CUB PF00431.20 OWF45025.1 - 0.012 16.0 0.0 0.057 13.8 0.0 2.2 1 0 0 1 1 1 0 CUB domain Adeno_E3_CR2 PF02439.15 OWF45025.1 - 0.29 10.9 0.6 0.54 10.1 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GMC_oxred_N PF00732.19 OWF45027.1 - 9.9e-87 291.0 0.1 1.4e-86 290.6 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF45027.1 - 2.3e-39 135.2 0.1 6e-39 133.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OWF45027.1 - 0.0038 17.4 0.5 0.01 16.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OWF45027.1 - 0.08 12.2 0.3 0.93 8.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 OWF45028.1 - 2.9e-91 305.9 0.0 3.7e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF45028.1 - 8.4e-40 136.6 0.2 2.9e-39 134.9 0.1 2.0 3 0 0 3 3 3 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF45028.1 - 5.7e-08 32.3 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OWF45028.1 - 0.00054 20.1 0.6 0.0018 18.5 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OWF45028.1 - 0.0023 17.2 0.3 0.43 9.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF45028.1 - 0.0046 16.2 0.0 0.037 13.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF45028.1 - 0.0062 16.2 0.6 0.018 14.7 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF45028.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 OWF45028.1 - 0.018 13.8 0.1 0.088 11.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 OWF45028.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OWF45028.1 - 0.12 11.4 0.8 2.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 OWF45029.1 - 4.7e-12 45.5 22.5 2.6e-11 43.1 22.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF45029.1 - 0.014 14.3 10.9 0.025 13.5 10.9 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter Glyco_transf_10 PF00852.19 OWF45030.1 - 1.7e-41 141.9 2.1 1e-40 139.3 0.9 2.3 1 1 1 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF45030.1 - 1.3e-22 80.3 0.6 1.3e-22 80.3 0.6 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Tachystatin_A PF11406.8 OWF45031.1 - 0.02 15.0 8.8 18 5.5 0.3 4.7 2 2 2 4 4 4 0 Antimicrobial peptide tachystatin A DUF4212 PF13937.6 OWF45032.1 - 0.024 15.0 1.1 1.2 9.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4212) Tachystatin_A PF11406.8 OWF45032.1 - 0.12 12.4 8.8 21 5.3 0.3 4.1 1 1 3 4 4 4 0 Antimicrobial peptide tachystatin A Glyco_transf_10 PF00852.19 OWF45033.1 - 2.3e-45 154.5 0.9 4.8e-45 153.4 0.9 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF45033.1 - 3e-23 82.4 0.8 3e-23 82.4 0.8 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal ArdA PF07275.11 OWF45033.1 - 0.11 13.1 0.1 0.4 11.2 0.0 2.0 3 0 0 3 3 3 0 Antirestriction protein (ArdA) Phage_XkdX PF09693.10 OWF45034.1 - 0.062 13.3 2.5 12 6.0 0.2 4.2 2 2 2 4 4 4 0 Phage uncharacterised protein (Phage_XkdX) CPW_WPC PF09717.10 OWF45034.1 - 0.08 13.9 8.3 8.3 7.5 0.7 4.2 1 1 3 4 4 4 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Sortilin_C PF15901.5 OWF45034.1 - 0.27 11.6 9.6 39 4.5 9.6 3.0 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, C-terminal BmKX PF09132.10 OWF45034.1 - 0.5 10.4 7.8 46 4.1 0.1 4.8 1 1 5 6 6 6 0 BmKX DUF5048 PF16467.5 OWF45034.1 - 0.73 10.1 5.1 10 6.4 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5048) Ins_beta PF03488.14 OWF45034.1 - 3.9 7.6 12.7 15 5.7 0.7 3.2 1 1 3 4 4 4 0 Nematode insulin-related peptide beta type AIG1 PF04548.16 OWF45035.1 - 1.1e-62 211.1 0.0 2.8e-62 209.8 0.0 1.7 1 0 0 1 1 1 1 AIG1 family ig PF00047.25 OWF45035.1 - 4.6e-20 71.6 6.8 2.5e-06 27.5 0.7 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 OWF45035.1 - 8.2e-19 68.0 5.0 2.6e-05 24.7 0.8 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF45035.1 - 1.3e-15 57.2 5.1 0.00017 21.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain V-set PF07686.17 OWF45035.1 - 1.1e-10 41.6 7.5 0.02 15.0 0.3 5.3 4 3 0 4 4 4 3 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF45035.1 - 4.4e-10 39.7 3.3 0.0043 17.4 0.3 3.6 3 0 0 3 3 3 2 Immunoglobulin domain MMR_HSR1 PF01926.23 OWF45035.1 - 1.1e-07 31.9 0.2 4.7e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF45035.1 - 0.011 15.2 0.0 0.031 13.8 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B Toprim PF01751.22 OWF45035.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 Toprim domain vATP-synt_E PF01991.18 OWF45035.1 - 1 8.7 10.2 2.6 7.4 10.2 1.7 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit PulA_N1 PF17999.1 OWF45035.1 - 4.8 8.0 6.3 63 4.4 0.0 4.2 5 0 0 5 5 4 0 Pullulanase N1-terminal domain PSA_CBD PF18341.1 OWF45036.1 - 0.00077 19.5 6.9 0.073 13.1 0.2 4.0 1 1 3 5 5 5 2 PSA endolysin C-terminal cell wall binding domain DUF3272 PF11676.8 OWF45036.1 - 0.062 13.6 5.0 14 6.0 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3272) MUG113 PF13455.6 OWF45036.1 - 0.096 13.4 0.4 8.5 7.1 0.1 2.3 1 1 1 2 2 2 0 Meiotically up-regulated gene 113 UPF0542 PF15086.6 OWF45036.1 - 1.3 9.0 3.0 3.2 7.7 0.2 2.6 2 1 0 3 3 3 0 Uncharacterised protein family UPF0542 HTH_21 PF13276.6 OWF45037.1 - 3.1e-06 27.2 1.3 3.1e-06 27.2 1.3 2.7 3 0 0 3 3 3 1 HTH-like domain rve PF00665.26 OWF45037.1 - 0.00033 20.8 0.0 0.0013 18.9 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain DUF5617 PF18493.1 OWF45037.1 - 0.18 11.9 0.9 24 5.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5617) p450 PF00067.22 OWF45038.1 - 1.7e-83 281.0 0.4 2e-83 280.7 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_FA PF12248.8 OWF45039.1 - 6.9e-19 68.1 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase Methyltransf_FA PF12248.8 OWF45040.1 - 3.2e-15 56.3 0.0 4.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase PAN_4 PF14295.6 OWF45040.1 - 0.00017 21.4 0.6 0.00038 20.3 0.6 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 OWF45040.1 - 0.00028 20.8 0.2 0.00055 19.9 0.2 1.4 1 0 0 1 1 1 1 PAN domain Hist_deacetyl PF00850.19 OWF45041.1 - 4.8e-86 289.0 0.0 6.3e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TTL PF03133.15 OWF45042.1 - 1.9e-83 280.0 0.1 1.1e-82 277.5 0.0 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF45042.1 - 2e-08 33.8 1.3 0.00056 19.2 0.0 3.4 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF45042.1 - 6.4e-05 22.3 0.0 0.11 11.7 0.0 3.0 2 1 1 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OWF45042.1 - 0.00084 19.4 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OWF45042.1 - 0.0038 16.9 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GTP-bdg_M PF16360.5 OWF45042.1 - 0.065 13.8 2.8 0.24 12.0 2.8 2.0 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region CABIT PF12736.7 OWF45043.1 - 1.7e-20 73.4 0.6 3.6e-18 65.9 0.3 3.0 1 1 1 2 2 2 2 Cell-cycle sustaining, positive selection, CABIT PF12736.7 OWF45044.1 - 2.3e-22 79.6 0.0 3.6e-21 75.7 0.0 2.1 1 1 1 2 2 2 2 Cell-cycle sustaining, positive selection, Inositol_P PF00459.25 OWF45045.1 - 5e-43 147.6 0.7 6.2e-43 147.3 0.7 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Rho_RNA_bind PF07497.12 OWF45045.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain UQ_con PF00179.26 OWF45046.1 - 1.4e-32 112.3 0.1 1.6e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_A PF14457.6 OWF45046.1 - 0.056 13.1 0.1 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A HP_OMP PF01856.17 OWF45046.1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Helicobacter outer membrane protein SRCR PF00530.18 OWF45047.1 - 1.7e-61 204.9 10.1 1.7e-24 86.2 0.1 3.1 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF45047.1 - 1.9e-14 53.9 8.0 4.4e-06 27.1 0.7 3.4 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF45047.1 - 1.2e-07 32.3 0.0 0.22 12.1 0.0 3.3 3 0 0 3 3 3 3 Hepsin, SRCR domain C1q PF00386.21 OWF45048.1 - 3.1e-18 66.2 1.3 3.3e-18 66.1 0.1 1.6 2 0 0 2 2 2 1 C1q domain Nup54 PF13874.6 OWF45048.1 - 0.017 15.2 3.0 0.018 15.2 1.9 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DHR10 PF18595.1 OWF45048.1 - 0.026 14.6 4.2 0.039 14.0 4.2 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain OGFr_N PF04664.13 OWF45048.1 - 0.056 13.0 0.3 0.095 12.2 0.3 1.3 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region SlyX PF04102.12 OWF45048.1 - 0.2 12.3 4.7 0.58 10.8 4.7 1.9 1 1 0 1 1 1 0 SlyX Cnn_1N PF07989.11 OWF45048.1 - 0.4 10.9 3.9 0.44 10.7 0.8 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 C1q PF00386.21 OWF45049.1 - 7.3e-22 77.9 0.1 9.4e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 C1q domain Lectin_C PF00059.21 OWF45050.1 - 6.4e-14 52.6 0.6 1e-13 52.0 0.2 1.6 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 OWF45050.1 - 0.029 14.3 1.3 0.035 14.1 0.3 1.6 2 0 0 2 2 2 0 PAN domain FF PF01846.19 OWF45050.1 - 0.079 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 FF domain Metallophos PF00149.28 OWF45054.1 - 8e-37 127.7 0.0 1.3e-36 127.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OWF45054.1 - 2.7e-32 110.9 0.8 7.3e-32 109.5 0.8 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 OWF45054.1 - 6.6e-16 57.4 6.5 2.8e-07 30.1 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF45054.1 - 3e-14 52.4 1.6 3.3e-08 33.1 0.3 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 OWF45054.1 - 2.9e-12 45.7 8.3 0.00017 21.4 0.1 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF45054.1 - 2.2e-09 36.8 1.4 0.0025 17.9 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF45054.1 - 1.5e-08 34.7 0.0 0.00042 20.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF45054.1 - 3.8e-05 24.3 0.3 0.015 16.0 0.1 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF45054.1 - 8e-05 23.2 0.0 0.24 12.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF45054.1 - 0.00071 19.8 3.2 0.015 15.7 0.4 3.6 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF45054.1 - 0.0025 18.4 0.6 2.3 9.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF45054.1 - 0.0035 17.8 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF45054.1 - 0.017 15.1 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF45054.1 - 0.022 14.8 0.1 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OWF45054.1 - 0.035 14.4 1.4 2.8 8.3 0.5 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OWF45054.1 - 0.07 13.6 0.4 14 6.2 0.0 2.5 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation HEPN PF05168.14 OWF45054.1 - 0.083 13.0 1.7 0.46 10.6 0.2 2.7 2 1 1 3 3 3 0 HEPN domain Glyco_transf_10 PF00852.19 OWF45055.1 - 4.9e-47 159.9 1.1 4.9e-47 159.9 1.1 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF45055.1 - 1e-16 61.4 0.2 3.7e-15 56.3 0.0 2.8 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal BEN PF10523.9 OWF45056.1 - 7.2e-10 39.0 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 BEN domain Kelch_1 PF01344.25 OWF45057.1 - 8.8e-65 214.1 15.4 5.4e-13 48.3 0.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF45057.1 - 2.9e-38 128.9 6.0 2.1e-08 34.1 0.0 6.5 3 2 3 6 6 6 5 Kelch motif BTB PF00651.31 OWF45057.1 - 2.6e-30 104.9 2.5 5.5e-30 103.9 2.5 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF45057.1 - 6.9e-30 103.2 2.0 6.9e-30 103.2 2.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 OWF45057.1 - 4.2e-23 80.4 11.3 3e-06 27.0 0.1 7.0 6 1 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OWF45057.1 - 3e-21 75.2 5.3 0.00048 20.4 0.1 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF45057.1 - 3.6e-14 52.5 11.0 0.00061 19.7 0.1 5.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF45057.1 - 9.3e-11 41.5 8.9 0.026 14.5 0.0 5.6 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 OWF45057.1 - 0.18 12.0 5.6 0.1 12.8 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) UvrD-helicase PF00580.21 OWF45057.1 - 0.24 10.9 0.6 0.32 10.4 0.6 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ABC_tran PF00005.27 OWF45058.1 - 4.4e-55 186.0 0.0 2e-26 93.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 OWF45058.1 - 3e-42 145.0 75.1 2.4e-35 122.3 20.8 4.4 4 1 0 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 OWF45058.1 - 2.4e-17 63.7 0.2 9.7e-07 28.9 0.0 4.1 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF45058.1 - 0.0015 19.1 2.5 1.4 9.4 0.1 3.1 3 0 0 3 3 3 2 AAA domain DUF4162 PF13732.6 OWF45058.1 - 0.074 13.8 0.0 0.48 11.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 OWF45058.1 - 0.09 12.7 0.4 1.3 8.9 0.1 2.9 2 0 0 2 2 2 0 RsgA GTPase F_actin_bind PF08919.10 OWF45058.1 - 0.1 12.7 1.2 8.3 6.6 0.0 3.8 2 0 0 2 2 2 0 F-actin binding ICEA PF05315.11 OWF45058.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 ICEA Protein AAA_30 PF13604.6 OWF45058.1 - 0.18 11.5 0.9 17 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain CHCH PF06747.13 OWF45060.1 - 2.1e-08 34.0 5.0 2.8e-08 33.7 5.0 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OWF45060.1 - 0.0076 16.2 4.3 0.012 15.6 4.3 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OWF45060.1 - 0.038 14.3 4.8 0.053 13.8 4.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 OWF45060.1 - 0.13 12.0 4.3 0.16 11.7 3.8 1.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) RRM_3 PF08777.11 OWF45061.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Ashwin PF15323.6 OWF45061.1 - 7.4 6.5 11.0 4.5 7.2 7.5 1.9 1 1 1 2 2 2 0 Developmental protein CD225 PF04505.12 OWF45062.1 - 1.1e-17 63.9 0.6 1.7e-17 63.3 0.6 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF2852 PF11014.8 OWF45062.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Ost4 PF10215.9 OWF45062.1 - 0.23 11.3 2.2 0.52 10.2 2.2 1.6 1 1 0 1 1 1 0 Oligosaccaryltransferase Peptidase_M41 PF01434.18 OWF45063.1 - 1e-57 195.1 0.0 2e-57 194.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OWF45063.1 - 7.6e-40 136.4 0.0 1.6e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF45063.1 - 3.5e-14 52.3 0.1 9.3e-14 51.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OWF45063.1 - 4.5e-05 23.9 1.1 0.0014 19.0 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OWF45063.1 - 0.00013 22.0 0.2 0.0005 20.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OWF45063.1 - 0.00015 21.6 0.1 0.00054 19.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OWF45063.1 - 0.00022 21.4 0.0 0.00088 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OWF45063.1 - 0.00032 20.0 0.0 0.00063 19.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 OWF45063.1 - 0.0026 18.2 0.1 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF45063.1 - 0.0028 18.0 0.1 0.15 12.3 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OWF45063.1 - 0.0036 17.5 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OWF45063.1 - 0.0078 15.6 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OWF45063.1 - 0.008 15.9 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OWF45063.1 - 0.014 16.0 0.0 0.049 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF45063.1 - 0.041 14.1 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OWF45063.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Kelch_1 PF01344.25 OWF45064.1 - 4.6e-33 112.6 14.8 1.7e-10 40.3 0.5 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OWF45064.1 - 2e-26 91.4 11.7 5e-08 32.9 0.1 6.7 3 2 3 6 6 6 5 Kelch motif BTB PF00651.31 OWF45064.1 - 3.1e-26 91.8 2.0 5.9e-26 90.9 0.9 2.0 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 OWF45064.1 - 4.2e-16 58.2 9.2 0.001 19.0 0.0 7.7 7 1 0 7 7 7 4 Kelch motif BACK PF07707.15 OWF45064.1 - 1.9e-14 53.6 0.1 3.9e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 OWF45064.1 - 3.3e-14 52.7 2.9 6e-06 26.4 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF45064.1 - 4.5e-14 52.2 5.0 0.0015 18.5 0.1 6.6 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF45064.1 - 2.5e-12 46.5 2.2 4.1e-05 23.5 0.1 4.4 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 OWF45064.1 - 0.026 14.7 1.3 0.78 10.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) S6PP_C PF08472.10 OWF45065.1 - 2.7e-06 27.3 2.3 0.58 10.0 0.1 5.3 1 1 5 6 6 6 1 Sucrose-6-phosphate phosphohydrolase C-terminal PH_18 PF18469.1 OWF45065.1 - 2.8e-06 27.4 0.0 32 4.5 0.0 5.5 3 1 3 6 6 6 0 Pleckstrin homology domain DCX PF03607.17 OWF45065.1 - 0.00019 21.4 0.0 17 5.6 0.0 5.3 1 1 5 6 6 6 1 Doublecortin DUF5124 PF17160.4 OWF45065.1 - 0.0002 22.0 0.8 59 4.5 0.0 5.1 1 1 4 6 6 6 0 Domain of unknown function (DUF5124) DUF5554 PF17709.1 OWF45065.1 - 0.00094 19.2 8.2 73 3.6 0.0 5.7 1 1 5 6 6 6 0 Family of unknown function (DUF5554) Tobravirus_2B PF05271.11 OWF45065.1 - 0.6 10.0 4.0 28 4.7 0.1 3.0 1 1 4 5 5 5 0 Tobravirus 2B protein Apidaecin PF00807.17 OWF45066.1 - 0.0047 17.0 22.1 64 3.8 0.0 10.1 1 1 11 13 13 13 0 Apidaecin HMD PF03201.16 OWF45066.1 - 0.0054 16.9 1.4 24 5.2 0.0 3.9 1 1 3 4 4 4 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase KH_10 PF17905.1 OWF45066.1 - 0.54 10.7 8.2 25 5.4 0.3 3.3 1 1 2 3 3 3 0 GLD-3 KH domain 5 DUF4620 PF15399.6 OWF45067.1 - 0.33 11.3 5.7 33 4.9 0.1 4.0 1 1 5 6 6 6 0 Domain of unknown function (DUF4620) DUF5014 PF16406.5 OWF45067.1 - 0.56 10.5 20.7 20 5.5 0.2 7.5 1 1 5 7 7 7 0 Domain of unknown function (DUF5014) ApbA_C PF08546.11 OWF45067.1 - 0.7 10.1 35.3 5.1 7.3 0.4 7.5 1 1 5 6 6 6 0 Ketopantoate reductase PanE/ApbA C terminal YjzC PF14168.6 OWF45067.1 - 0.94 9.9 35.9 1.4 9.3 0.7 7.3 1 1 7 8 8 8 0 YjzC-like protein ESPR PF13018.6 OWF45070.1 - 0.37 10.6 8.0 57 3.6 0.2 6.8 3 0 0 3 3 3 0 Extended Signal Peptide of Type V secretion system OTU PF02338.19 OWF45071.1 - 2e-29 102.6 2.3 5e-29 101.4 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OWF45071.1 - 1.3e-06 28.1 6.4 0.012 15.1 0.0 3.3 1 1 1 3 3 3 2 Peptidase C65 Otubain DUF3915 PF13054.6 OWF45071.1 - 0.013 15.5 2.6 0.013 15.5 2.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3915) Baculo_PEP_C PF04513.12 OWF45071.1 - 0.031 14.3 3.7 3.6 7.6 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DELLA PF12041.8 OWF45071.1 - 0.14 12.1 1.2 0.44 10.5 0.2 2.3 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal DDHD PF02862.17 OWF45071.1 - 3 8.0 6.1 3.7 7.6 6.1 1.3 1 0 0 1 1 1 0 DDHD domain FUSC PF04632.12 OWF45071.1 - 3.2 6.2 4.6 3.8 5.9 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ndc1_Nup PF09531.10 OWF45071.1 - 6.1 5.4 5.3 6.4 5.3 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spc7 PF08317.11 OWF45071.1 - 9.5 5.0 31.0 0.54 9.1 10.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein HEM4 PF02602.15 OWF45072.1 - 0.078 12.3 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Cys_rich_FGFR PF00839.17 OWF45073.1 - 2.5e-155 504.7 109.3 7.7e-14 51.6 0.5 16.4 16 0 0 16 16 16 16 Cysteine rich repeat Biopterin_H PF00351.21 OWF45073.1 - 0.064 12.3 1.0 0.14 11.2 0.1 1.8 2 0 0 2 2 2 0 Biopterin-dependent aromatic amino acid hydroxylase Rab5ip PF07019.12 OWF45074.1 - 1e-13 51.6 2.1 1.8e-13 50.9 2.1 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) UQ_con PF00179.26 OWF45075.1 - 4.5e-22 78.2 0.0 6.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NUDIX PF00293.28 OWF45076.1 - 4.1e-11 43.0 0.1 8.6e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 OWF45077.1 - 4.6e-11 42.9 0.0 6.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RHD_dimer PF16179.5 OWF45078.1 - 6.7e-24 83.9 0.3 6.7e-24 83.9 0.3 2.9 3 0 0 3 3 3 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 OWF45078.1 - 2.2e-20 73.3 0.2 2.2e-20 73.3 0.2 4.2 4 1 0 4 4 4 1 Rel homology DNA-binding domain TIG PF01833.24 OWF45078.1 - 8.7e-05 22.5 0.0 8.7e-05 22.5 0.0 4.8 4 1 1 5 5 5 1 IPT/TIG domain Asp-B-Hydro_N PF05279.11 OWF45078.1 - 0.65 10.0 12.0 1.5 8.8 12.0 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Membralin PF09746.9 OWF45078.1 - 10 5.1 10.2 27 3.7 10.2 1.8 1 0 0 1 1 1 0 Tumour-associated protein DUF2347 PF09804.9 OWF45079.1 - 5.4e-74 249.3 0.0 8e-74 248.7 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 OWF45079.1 - 1.1e-12 47.4 0.2 1.5e-09 37.1 0.0 2.5 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 OWF45079.1 - 1.3e-11 44.5 0.1 2.9e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF4484 PF14831.6 OWF45079.1 - 0.0043 17.1 0.5 0.019 15.0 0.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) TrkA_C PF02080.21 OWF45080.1 - 0.033 14.0 0.5 1 9.2 0.1 2.2 1 1 1 2 2 2 0 TrkA-C domain zf-C2H2 PF00096.26 OWF45081.1 - 2.2e-24 84.5 33.0 4.2e-07 30.1 1.5 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF45081.1 - 3.6e-19 68.3 31.1 1.4e-08 34.7 1.5 5.9 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF45081.1 - 9.7e-17 60.2 38.2 0.00016 22.2 1.4 6.1 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF45081.1 - 8.5e-08 32.3 10.8 0.38 11.1 0.2 4.7 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OWF45081.1 - 2.6e-05 23.9 21.6 0.0063 16.3 1.4 5.5 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 OWF45081.1 - 0.0038 17.2 27.2 0.011 15.8 1.6 5.6 6 0 0 6 6 6 2 C2H2-type zinc finger zf-Di19 PF05605.12 OWF45081.1 - 0.018 15.3 19.5 0.62 10.4 3.7 4.4 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 OWF45081.1 - 0.023 14.3 16.7 3.1 7.5 0.1 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 OWF45081.1 - 0.051 13.5 8.0 39 4.3 0.0 5.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger ROS_MUCR PF05443.11 OWF45081.1 - 0.068 13.2 1.4 2.6 8.1 0.2 2.7 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein HypA PF01155.19 OWF45081.1 - 0.076 13.0 14.1 2 8.5 1.3 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 OWF45081.1 - 0.13 12.3 28.9 0.43 10.6 1.9 5.4 1 1 3 4 4 4 0 BED zinc finger Zn-ribbon_8 PF09723.10 OWF45081.1 - 0.14 12.3 23.7 0.28 11.4 0.5 4.5 5 1 0 5 5 5 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 OWF45081.1 - 0.18 12.2 19.0 4.8 7.6 0.2 4.8 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.18 OWF45081.1 - 0.52 10.4 20.6 4.3 7.5 0.1 5.2 5 0 0 5 5 5 0 XPA protein N-terminal FYDLN_acid PF09538.10 OWF45081.1 - 0.89 10.3 12.4 6.6 7.5 0.3 4.4 2 2 3 5 5 5 0 Protein of unknown function (FYDLN_acid) zf-H2C2_5 PF13909.6 OWF45081.1 - 0.96 9.3 0.0 0.96 9.3 0.0 5.9 7 0 0 7 7 6 0 C2H2-type zinc-finger domain TerY_C PF15616.6 OWF45081.1 - 4.9 7.3 11.4 12 6.0 0.3 3.0 1 1 2 3 3 3 0 TerY-C metal binding domain zinc_ribbon_15 PF17032.5 OWF45081.1 - 7.7 7.3 20.6 17 6.3 6.4 3.5 3 1 1 4 4 3 0 zinc-ribbon family Rpr2 PF04032.16 OWF45081.1 - 8.1 6.8 16.2 0.48 10.8 0.7 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain ADK_lid PF05191.14 OWF45081.1 - 9.3 6.3 17.1 0.63 10.1 2.6 3.5 2 1 1 3 3 3 0 Adenylate kinase, active site lid MTTB PF06253.11 OWF45083.1 - 0.069 11.1 0.0 0.09 10.7 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Mab-21 PF03281.14 OWF45084.1 - 1.9e-31 109.5 0.2 3e-31 108.8 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_1 PF00515.28 OWF45084.1 - 0.034 14.0 0.1 4.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mab-21 PF03281.14 OWF45085.1 - 1.9e-31 109.5 0.2 3e-31 108.8 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_1 PF00515.28 OWF45085.1 - 0.034 14.0 0.1 4.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF PF00209.18 OWF45086.1 - 2.3e-166 554.6 33.5 2.6e-166 554.4 33.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CRAL_TRIO PF00650.20 OWF45087.1 - 5.3e-22 78.2 0.0 8.5e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OWF45087.1 - 3.3e-07 30.4 0.1 8.1e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Abhydrolase_1 PF00561.20 OWF45088.1 - 1.3e-24 87.2 0.1 2.8e-24 86.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF45088.1 - 2.2e-18 67.7 0.2 3.6e-18 67.0 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF45088.1 - 2.5e-13 49.9 0.0 4.5e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OWF45088.1 - 1.2e-07 30.7 0.0 1.3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 OWF45088.1 - 0.0011 18.7 0.0 0.0033 17.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OWF45088.1 - 0.0016 18.0 0.0 0.0065 16.1 0.0 1.9 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 OWF45088.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 OWF45088.1 - 0.0028 17.8 0.0 0.0064 16.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain PAF-AH_p_II PF03403.13 OWF45088.1 - 0.0048 15.5 0.0 0.085 11.4 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.11 OWF45088.1 - 0.015 14.7 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 OWF45088.1 - 0.02 14.8 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 OWF45088.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OWF45088.1 - 0.027 14.2 0.0 0.073 12.8 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S10 PF00450.22 OWF45088.1 - 0.048 13.1 0.2 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Serine carboxypeptidase Palm_thioest PF02089.15 OWF45088.1 - 0.05 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 OWF45088.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 OWF45088.1 - 0.086 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 OWF45088.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 OWF45088.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2920 PF11144.8 OWF45088.1 - 0.14 11.3 0.0 0.82 8.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) DUF5472 PF17566.2 OWF45089.1 - 0.17 11.9 0.3 0.56 10.2 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5472) Ank_2 PF12796.7 OWF45090.1 - 1.9e-28 98.8 0.9 2.3e-13 50.5 0.1 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF45090.1 - 4.5e-23 80.6 1.3 0.00028 21.2 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OWF45090.1 - 1.1e-22 79.7 0.1 1.6e-07 31.4 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF45090.1 - 1.5e-21 76.5 1.3 1.6e-05 25.4 0.1 4.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF45090.1 - 2.1e-17 61.4 0.3 0.0033 17.8 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat DUF1104 PF06518.11 OWF45090.1 - 2 8.9 6.5 0.49 10.8 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1104) Alpha_L_fucos PF01120.17 OWF45091.1 - 5.6e-60 203.7 0.4 7.6e-60 203.2 0.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF45091.1 - 9.4e-26 90.2 0.1 1.7e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 OWF45091.1 - 0.025 14.7 0.5 0.083 13.0 0.5 1.9 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator PUB PF09409.10 OWF45092.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 PUB domain zf-RanBP PF00641.18 OWF45092.1 - 0.0002 20.6 14.3 0.019 14.3 2.1 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 OWF45092.1 - 0.66 10.0 11.5 1.3 9.1 11.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 OWF45093.1 - 1.6e-25 88.0 32.1 5.8e-06 26.5 0.6 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF45093.1 - 3.3e-20 71.0 28.3 0.00047 20.8 0.4 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF45093.1 - 1.1e-16 60.4 30.7 4.5e-05 23.7 1.4 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF45093.1 - 1.2e-11 44.3 31.8 0.0025 17.8 3.6 5.7 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 OWF45093.1 - 7.8e-07 29.3 24.7 0.17 12.3 1.6 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF45093.1 - 1.3e-06 28.5 25.7 0.073 13.4 0.1 5.6 6 0 0 6 6 5 4 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 OWF45093.1 - 5.2e-05 23.2 22.6 0.048 13.7 0.4 5.2 2 1 3 5 5 5 2 BED zinc finger zf_UBZ PF18439.1 OWF45093.1 - 0.00015 21.3 12.1 0.19 11.3 0.1 5.1 5 0 0 5 5 5 1 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 OWF45093.1 - 0.0029 17.6 16.3 2.4 8.3 1.6 5.0 5 0 0 5 5 5 1 XPA protein N-terminal Zn-ribbon_8 PF09723.10 OWF45093.1 - 0.0032 17.6 14.5 0.57 10.3 0.3 4.1 3 2 0 3 3 3 2 Zinc ribbon domain zf-Di19 PF05605.12 OWF45093.1 - 0.0036 17.6 19.5 0.091 13.1 3.0 4.1 1 1 3 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OWF45093.1 - 0.0068 16.1 19.9 0.11 12.2 0.4 5.2 5 0 0 5 5 5 2 zinc-finger C2H2-type C1_4 PF07975.12 OWF45093.1 - 0.037 14.2 15.9 0.78 10.0 2.1 3.6 2 1 1 3 3 3 0 TFIIH C1-like domain HypA PF01155.19 OWF45093.1 - 0.047 13.7 12.1 0.63 10.1 1.3 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 OWF45093.1 - 0.06 14.1 15.6 0.38 11.5 1.3 2.9 2 1 0 2 2 2 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 OWF45093.1 - 0.071 13.8 8.6 4.3 8.0 0.1 3.7 2 2 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 OWF45093.1 - 0.18 12.3 4.2 6.5 7.3 0.3 4.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 OWF45093.1 - 0.27 11.3 18.2 1.1e+04 -3.5 18.2 3.3 1 1 0 1 1 0 0 Double zinc ribbon zf-LYAR PF08790.11 OWF45093.1 - 0.42 10.6 11.0 14 5.7 0.4 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zinc-ribbons_6 PF07191.12 OWF45093.1 - 0.83 9.7 14.5 3.8 7.6 2.1 3.8 2 2 0 2 2 2 0 zinc-ribbons DUF2256 PF10013.9 OWF45093.1 - 0.91 9.7 11.6 9.5 6.4 0.0 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 OWF45093.1 - 0.97 9.6 19.9 9.5 6.4 1.2 3.7 1 1 1 2 2 2 0 FYVE zinc finger Nudix_N_2 PF14803.6 OWF45093.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.9 5 0 0 5 5 5 0 Nudix N-terminal HNH_5 PF14279.6 OWF45093.1 - 1.5 8.7 11.9 1.2 9.1 1.4 4.3 3 2 0 4 4 4 0 HNH endonuclease Rpr2 PF04032.16 OWF45093.1 - 1.8 8.9 14.3 4.5 7.6 0.2 3.0 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.6 OWF45093.1 - 2 7.9 15.8 7 6.2 0.1 4.9 5 0 0 5 5 5 0 zinc-ribbon domain Ribosomal_L37ae PF01780.19 OWF45093.1 - 2.1 8.5 17.6 1.1 9.4 0.3 4.8 2 2 2 4 4 4 0 Ribosomal L37ae protein family zf-AN1 PF01428.16 OWF45093.1 - 2.6 8.3 21.8 11 6.2 0.4 5.4 4 1 1 5 5 5 0 AN1-like Zinc finger CpXC PF14353.6 OWF45093.1 - 3.7 7.6 15.2 9.3 6.3 0.2 4.6 2 2 3 5 5 5 0 CpXC protein PknG_rubred PF16919.5 OWF45093.1 - 4.5 7.4 9.3 3.8 7.7 0.2 3.0 1 1 2 3 3 3 0 Protein kinase G rubredoxin domain zf-C2H2_2 PF12756.7 OWF45093.1 - 4.8 7.6 21.3 2.6 8.4 2.6 4.3 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-MYND PF01753.18 OWF45093.1 - 4.9 7.3 15.7 4 7.6 2.4 3.5 2 1 1 3 3 3 0 MYND finger Sprouty PF05210.13 OWF45093.1 - 7.3 7.0 13.6 0.29 11.5 1.9 3.2 2 1 0 2 2 2 0 Sprouty protein (Spry) zf-C2HC_2 PF13913.6 OWF45093.1 - 9.5 6.3 23.7 0.64 10.0 0.5 4.8 5 0 0 5 5 4 0 zinc-finger of a C2HC-type NUDIX_2 PF13869.6 OWF45095.1 - 1.2e-76 256.5 0.0 1.4e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Arm PF00514.23 OWF45096.1 - 1.2e-05 25.2 0.4 8.8e-05 22.4 0.4 2.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OWF45096.1 - 0.0094 16.4 0.4 0.059 13.9 0.1 2.5 2 0 0 2 2 2 1 HEAT-like repeat VWA PF00092.28 OWF45097.1 - 1.9e-181 598.1 24.7 2.6e-48 164.5 1.9 4.1 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_2 PF13519.6 OWF45097.1 - 5.2e-65 216.8 2.5 9.8e-19 68.0 0.0 4.3 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_3 PF13768.6 OWF45097.1 - 3.5e-22 79.0 0.0 0.00012 22.0 0.0 4.4 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF45097.1 - 1.8e-11 43.9 0.0 0.0012 18.2 0.0 4.3 4 0 0 4 4 4 4 VWA domain containing CoxE-like protein TSP_1 PF00090.19 OWF45097.1 - 2.7e-11 43.5 7.4 2.7e-11 43.5 7.4 6.5 8 0 0 8 8 8 1 Thrombospondin type 1 domain ShK PF01549.24 OWF45097.1 - 3.4e-06 27.5 23.7 2.2e-05 24.9 8.1 11.0 11 0 0 11 11 11 6 ShK domain-like VWC PF00093.18 OWF45097.1 - 9.4e-05 22.6 265.0 0.0026 18.0 13.3 13.5 13 2 2 15 15 15 9 von Willebrand factor type C domain Copine PF07002.16 OWF45097.1 - 0.00029 20.4 5.1 2.2 7.7 0.0 3.9 4 0 0 4 4 4 3 Copine Ank_2 PF12796.7 OWF45098.1 - 2.2e-05 24.9 0.1 5.7e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ubiquitin_2 PF14560.6 OWF45098.1 - 0.00096 19.6 0.0 0.016 15.7 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-like domain Ank_3 PF13606.6 OWF45098.1 - 0.0029 18.0 0.1 6 7.8 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OWF45098.1 - 0.0068 17.0 0.1 0.018 15.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ubiquitin PF00240.23 OWF45098.1 - 0.051 13.3 0.0 0.46 10.3 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family Ank PF00023.30 OWF45098.1 - 0.15 12.5 0.3 65 4.2 0.0 3.5 3 1 0 3 3 3 0 Ankyrin repeat DUF4207 PF13904.6 OWF45098.1 - 0.69 9.6 9.9 1.2 8.8 2.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4207) DAO PF01266.24 OWF45099.1 - 9.6e-22 78.0 0.0 1.2e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OWF45099.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF45100.1 - 2.3e-42 145.9 0.1 2.6e-42 145.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OWF45100.1 - 0.0018 17.0 0.1 0.066 11.9 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 OWF45100.1 - 0.0098 15.2 0.1 0.032 13.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 OWF45101.1 - 4.5e-66 222.0 0.0 7.9e-66 221.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF45101.1 - 6.4e-28 97.3 0.1 1.7e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 OWF45101.1 - 3e-19 69.3 0.1 7.2e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 SPRY domain ERCC3_RAD25_C PF16203.5 OWF45101.1 - 7.6e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OWF45101.1 - 0.0098 15.3 0.1 0.038 13.3 0.1 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Pkinase_Tyr PF07714.17 OWF45102.1 - 3e-41 141.4 0.8 4.5e-25 88.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OWF45102.1 - 3.7e-26 92.1 2.3 2.4e-16 59.9 0.0 3.6 4 1 0 4 4 4 2 Protein kinase domain Cupin_6 PF12852.7 OWF45102.1 - 0.069 12.9 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Cupin Pkinase_Tyr PF07714.17 OWF45103.1 - 6.2e-44 150.2 0.5 2.8e-26 92.4 0.0 3.5 3 1 1 4 4 4 2 Protein tyrosine kinase Pkinase PF00069.25 OWF45103.1 - 2.1e-21 76.5 1.0 9.1e-13 48.2 0.0 3.4 5 0 0 5 5 5 2 Protein kinase domain BEN PF10523.9 OWF45104.1 - 1.3e-06 28.5 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 BEN domain Glyco_transf_90 PF05686.12 OWF45105.1 - 1.4e-74 251.3 0.1 1.3e-66 225.2 0.2 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 90 Filamin PF00630.19 OWF45105.1 - 6.7e-06 26.9 0.0 1.4e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat DUF3689 PF12463.8 OWF45106.1 - 4.9e-138 459.7 10.2 4.9e-138 459.7 10.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3689) TPR_2 PF07719.17 OWF45108.1 - 5.5e-06 26.1 5.5 1.7 8.9 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF45108.1 - 6.1e-05 22.7 7.7 0.26 11.2 0.8 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF45108.1 - 9.1e-05 22.4 3.5 0.54 10.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF45108.1 - 0.00037 20.9 0.8 0.032 14.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF45108.1 - 0.00099 18.7 0.1 2.6 7.8 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_7 PF13176.6 OWF45108.1 - 0.0013 18.6 0.8 0.14 12.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF45108.1 - 0.0015 18.7 0.2 2.1 8.9 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF45108.1 - 0.011 16.0 1.1 0.96 9.8 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF45108.1 - 0.032 15.0 1.7 15 6.7 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 OWF45109.1 - 5.9e-14 52.4 0.0 1.8e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF45109.1 - 2.6e-05 23.8 0.0 5.3e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OWF45109.1 - 0.0001 21.9 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 OWF45109.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) COesterase PF00135.28 OWF45109.1 - 0.015 14.2 0.0 0.2 10.5 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_6 PF12697.7 OWF45109.1 - 0.082 13.5 0.0 0.2 12.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family CAP PF00188.26 OWF45110.1 - 3.6e-22 79.5 2.4 4e-22 79.4 1.5 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_S26 PF10502.9 OWF45111.1 - 1.5e-07 31.3 0.0 0.00016 21.5 0.0 2.6 2 1 1 3 3 3 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OWF45111.1 - 0.00026 20.9 0.1 0.00086 19.2 0.1 1.9 1 1 0 1 1 1 1 Peptidase S24-like ubiquitin PF00240.23 OWF45112.1 - 9e-09 35.0 0.0 2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF4834 PF16118.5 OWF45112.1 - 0.00085 20.3 0.3 0.0027 18.6 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF2407 PF10302.9 OWF45112.1 - 0.00089 19.8 5.2 0.0014 19.1 0.0 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Presenilin PF01080.17 OWF45112.1 - 0.0011 17.8 1.1 0.0019 17.1 1.1 1.4 1 0 0 1 1 1 1 Presenilin Rad60-SLD_2 PF13881.6 OWF45112.1 - 0.0056 16.8 0.0 0.0056 16.8 0.0 2.2 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like CBP_BcsG PF11658.8 OWF45112.1 - 0.011 14.2 0.1 0.019 13.4 0.1 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG MAP17 PF15807.5 OWF45112.1 - 0.015 15.6 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HCO3_cotransp PF00955.21 OWF45112.1 - 0.016 14.1 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 HCO3- transporter family SpoIIP PF07454.11 OWF45112.1 - 0.027 13.9 1.6 0.053 13.0 1.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2370 PF10176.9 OWF45112.1 - 0.033 13.8 0.8 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Kei1 PF08552.11 OWF45112.1 - 0.036 13.9 0.5 0.071 13.0 0.5 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ctr PF04145.15 OWF45112.1 - 0.054 14.1 0.1 0.12 13.0 0.1 1.6 1 0 0 1 1 1 0 Ctr copper transporter family Peroxin-13_N PF04088.13 OWF45112.1 - 0.076 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Peroxin 13, N-terminal region SID-1_RNA_chan PF13965.6 OWF45112.1 - 0.1 11.0 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 OWF45112.1 - 0.15 11.0 0.7 0.27 10.2 0.7 1.3 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 OWF45112.1 - 0.16 12.1 1.3 0.3 11.2 1.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.8 OWF45112.1 - 0.81 9.4 3.7 1.8 8.3 3.7 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 OWF45112.1 - 2.1 7.0 9.7 3.5 6.3 9.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.13 OWF45112.1 - 3.2 8.4 33.4 4.3 8.0 18.8 3.1 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SARAF PF06682.12 OWF45112.1 - 4 7.0 9.5 1 9.0 6.5 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF913 PF06025.12 OWF45112.1 - 5.2 5.9 6.5 8.7 5.2 6.3 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Peroxin-3 PF04882.12 OWF45112.1 - 5.9 5.8 12.5 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Peroxin-3 Pkinase PF00069.25 OWF45113.1 - 1.7e-58 198.0 0.0 2.2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF45113.1 - 7.8e-35 120.4 0.0 9.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF45113.1 - 1.7e-11 44.0 0.0 1.4e-10 40.9 0.0 2.1 1 1 2 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OWF45113.1 - 0.12 11.1 0.0 0.29 9.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OWF45113.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5507 PF17612.2 OWF45113.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5507) STE3 PF02076.15 OWF45113.1 - 0.21 10.7 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Pheromone A receptor TAFH PF07531.14 OWF45114.1 - 2.1e-34 117.5 1.7 4.7e-34 116.4 1.7 1.6 1 0 0 1 1 1 1 NHR1 homology to TAF NHR2 PF08788.11 OWF45114.1 - 3.5e-20 71.5 1.6 9.3e-20 70.2 1.6 1.7 1 0 0 1 1 1 1 NHR2 domain like zf-MYND PF01753.18 OWF45114.1 - 2.4e-07 30.7 16.8 4.2e-07 29.9 16.8 1.4 1 0 0 1 1 1 1 MYND finger HscB_4_cys PF18256.1 OWF45114.1 - 4.8 7.1 6.6 18 5.3 6.6 2.0 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Glyco_hydro_20 PF00728.22 OWF45115.1 - 4.4e-147 490.1 4.4 1.3e-65 222.2 0.1 3.5 2 1 1 3 3 3 3 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OWF45115.1 - 4.5e-36 124.5 1.4 3.1e-18 66.8 0.1 2.9 3 0 0 3 3 3 2 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OWF45115.1 - 3.3e-15 57.0 0.0 4.7e-06 27.4 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.6 OWF45115.1 - 0.024 14.8 0.0 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Ly49 PF08391.10 OWF45116.1 - 2.7e-07 31.0 22.4 0.81 10.1 0.3 7.4 1 1 7 8 8 8 7 Ly49-like protein, N-terminal region AIG1 PF04548.16 OWF45116.1 - 3.5 6.9 5.7 93 2.2 0.1 3.8 3 1 2 5 5 5 0 AIG1 family MFS_1 PF07690.16 OWF45119.1 - 6.6e-11 41.7 42.2 2.8e-07 29.8 28.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF308 PF03729.13 OWF45119.1 - 0.021 15.2 6.8 0.021 15.2 6.8 5.1 3 1 1 4 4 4 0 Short repeat of unknown function (DUF308) Glyco_transf_7N PF13733.6 OWF45120.1 - 6.3e-54 181.2 0.0 1e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF45120.1 - 7.6e-28 96.0 0.1 1.7e-27 94.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Galactosyl_T PF01762.21 OWF45123.1 - 9.6e-35 120.2 0.2 4.4e-34 118.0 0.0 1.9 1 1 1 2 2 2 1 Galactosyltransferase Herpes_heli_pri PF05774.11 OWF45123.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component MAPEG PF01124.18 OWF45124.1 - 3.4e-10 39.9 0.8 4.5e-10 39.5 0.8 1.2 1 0 0 1 1 1 1 MAPEG family HCO3_cotransp PF00955.21 OWF45125.1 - 4.7e-164 547.0 8.5 1e-163 545.8 8.5 1.5 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 OWF45125.1 - 0.00013 21.9 0.6 0.36 10.6 0.0 2.2 2 0 0 2 2 2 2 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 OWF45125.1 - 0.0025 17.7 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 UAE_UbL PF14732.6 OWF45125.1 - 0.11 13.1 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain RVT_1 PF00078.27 OWF45126.1 - 8.4e-43 146.4 0.7 8.4e-43 146.4 0.7 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OWF45126.1 - 5e-05 23.1 0.0 0.0065 16.3 0.0 3.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Asparaginase_2 PF01112.18 OWF45127.1 - 3.5e-68 229.9 1.4 4.8e-68 229.4 1.4 1.0 1 0 0 1 1 1 1 Asparaginase ASC PF00858.24 OWF45129.1 - 4e-54 184.2 3.1 6.2e-54 183.6 3.1 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Cmc1 PF08583.10 OWF45129.1 - 0.075 13.1 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Antimicrobial21 PF14861.6 OWF45129.1 - 0.19 11.4 0.4 0.36 10.6 0.4 1.4 1 0 0 1 1 1 0 Plant antimicrobial peptide ASC PF00858.24 OWF45130.1 - 9.8e-79 265.4 8.3 1.3e-78 265.0 8.3 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Aa_trans PF01490.18 OWF45131.1 - 2.6e-73 247.1 16.5 6.8e-58 196.3 19.2 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Polysacc_deac_1 PF01522.21 OWF45133.1 - 3.2e-05 23.8 0.0 6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 OWF45134.1 - 2.4e-10 40.3 0.3 2.6e-09 37.0 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide deacetylase SGS PF05002.15 OWF45135.1 - 4.3e-34 116.5 2.5 9.4e-34 115.4 2.5 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OWF45135.1 - 7.7e-17 62.1 3.6 1.7e-16 61.0 3.6 1.7 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 OWF45135.1 - 4.4e-16 57.9 4.7 5.1e-05 22.9 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF45135.1 - 1.6e-13 49.6 6.2 0.00079 19.4 0.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF45135.1 - 2.5e-12 47.1 0.8 3.3e-06 27.5 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF45135.1 - 8.3e-09 35.2 0.2 0.0023 18.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF45135.1 - 1.6e-08 34.1 1.1 2.1e-05 24.1 0.7 2.7 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 OWF45135.1 - 7.6e-08 32.0 4.6 0.0081 16.3 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF45135.1 - 1.5e-07 31.9 2.9 9.2e-05 23.0 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Polysacc_deac_1 PF01522.21 OWF45135.1 - 1.8e-06 27.9 0.0 6.4e-06 26.1 0.0 2.0 2 1 0 2 2 1 1 Polysaccharide deacetylase TPR_14 PF13428.6 OWF45135.1 - 4.9e-06 26.9 0.8 0.15 13.0 0.0 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF45135.1 - 2e-05 24.7 2.1 4e-05 23.8 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OWF45135.1 - 0.0043 17.2 0.0 0.24 11.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF627 PF04781.12 OWF45135.1 - 0.0048 16.9 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF627) TPR_12 PF13424.6 OWF45135.1 - 0.015 15.6 4.7 0.081 13.2 0.4 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OWF45135.1 - 0.043 13.9 1.9 0.58 10.3 0.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 OWF45135.1 - 0.24 11.5 6.6 2.2 8.5 0.1 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat RPN6_N PF18055.1 OWF45135.1 - 0.4 11.1 2.2 0.7 10.3 0.9 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_6 PF13174.6 OWF45135.1 - 4 8.3 6.2 32 5.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Torsin PF06309.11 OWF45137.1 - 1.4e-90 299.9 2.3 2.9e-45 153.4 0.3 2.4 2 0 0 2 2 2 2 Torsin AAA PF00004.29 OWF45137.1 - 2.6e-07 31.1 0.1 0.015 15.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 OWF45137.1 - 1e-06 29.0 0.3 0.038 14.1 0.1 3.4 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OWF45137.1 - 0.00016 21.7 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OWF45137.1 - 0.00036 20.3 0.1 0.92 9.2 0.1 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 OWF45137.1 - 0.00081 19.4 0.1 0.66 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 OWF45137.1 - 0.0032 17.5 0.1 1.8 8.6 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OWF45137.1 - 0.006 16.3 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_26 PF13500.6 OWF45137.1 - 0.051 13.4 0.0 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SUV3_C PF12513.8 OWF45137.1 - 0.069 13.1 0.1 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF87 PF01935.17 OWF45137.1 - 0.15 12.1 0.3 9.2 6.3 0.1 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain TMEM144 PF07857.12 OWF45138.1 - 5e-103 344.6 9.5 6.4e-103 344.2 9.5 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 OWF45138.1 - 1.8e-06 27.5 7.7 4.5e-06 26.2 0.2 2.5 2 0 0 2 2 2 2 Sugar transport protein Maff2 PF12750.7 OWF45138.1 - 0.0013 18.5 1.0 0.0047 16.7 1.0 2.0 1 0 0 1 1 1 1 Maff2 family RWD PF05773.22 OWF45139.1 - 1.8e-16 60.4 0.0 3.8e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 OWF45139.1 - 5.8e-16 58.9 0.3 3.2e-15 56.5 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Ndc80_HEC PF03801.13 OWF45139.1 - 0.073 12.7 0.5 0.22 11.2 0.1 2.1 2 1 0 2 2 2 0 HEC/Ndc80p family SSF PF00474.17 OWF45140.1 - 5.4e-08 32.1 20.1 1.1e-07 31.1 20.1 1.6 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3341 PF11821.8 OWF45140.1 - 0.0082 15.8 0.5 0.0082 15.8 0.5 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3341) Phage_holin_6_1 PF09682.10 OWF45140.1 - 0.1 13.0 1.1 10 6.6 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) SSF PF00474.17 OWF45141.1 - 6.8e-07 28.5 24.8 1.5e-05 24.1 14.9 2.3 2 0 0 2 2 2 2 Sodium:solute symporter family DUF2070 PF09843.9 OWF45141.1 - 3.5 5.8 17.6 0.11 10.7 3.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) PAN_1 PF00024.26 OWF45142.1 - 0.0055 16.7 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 PAN domain SSF PF00474.17 OWF45144.1 - 0.00038 19.5 0.4 0.00039 19.4 0.4 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 OWF45145.1 - 5e-06 25.6 25.6 5e-06 25.6 25.6 2.7 3 0 0 3 3 3 2 Sodium:solute symporter family Phage_holin_6_1 PF09682.10 OWF45145.1 - 0.046 14.1 0.1 33 5.0 0.1 3.7 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) SSF PF00474.17 OWF45146.1 - 4.2e-11 42.4 19.9 4.2e-11 42.4 19.9 2.6 3 0 0 3 3 3 2 Sodium:solute symporter family DUF4231 PF14015.6 OWF45146.1 - 1.5 9.4 5.2 0.86 10.1 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF3341 PF11821.8 OWF45146.1 - 4.3 6.9 11.6 0.08 12.6 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) CUB PF00431.20 OWF45147.1 - 0.00055 20.3 0.1 0.00069 19.9 0.1 1.1 1 0 0 1 1 1 1 CUB domain cEGF PF12662.7 OWF45148.1 - 8.3e-71 233.5 170.4 3e-08 33.4 2.2 21.2 19 1 0 19 19 19 17 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF45148.1 - 1.3e-66 220.5 297.2 4.8e-08 33.1 11.5 21.7 20 2 1 21 21 21 16 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 OWF45148.1 - 7e-64 211.8 309.0 1.1e-09 38.3 7.8 21.7 18 2 2 20 20 20 15 Calcium-binding EGF domain Ephrin_rec_like PF07699.13 OWF45148.1 - 1.1e-24 86.0 86.7 3.1e-08 33.2 5.7 11.1 7 1 4 11 11 11 7 Putative ephrin-receptor like EGF_3 PF12947.7 OWF45148.1 - 0.0073 16.5 4.7 0.0073 16.5 4.7 20.3 17 2 1 18 18 18 10 EGF domain EGF PF00008.27 OWF45148.1 - 0.014 15.7 4.5 0.014 15.7 4.5 20.0 18 0 0 18 18 18 0 EGF-like domain TNFR_c6 PF00020.18 OWF45148.1 - 0.029 14.8 0.6 0.029 14.8 0.6 13.9 9 3 5 14 14 14 0 TNFR/NGFR cysteine-rich region DUF4375 PF14300.6 OWF45148.1 - 0.13 12.5 0.0 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF2048 PF09752.9 OWF45149.1 - 2.8e-133 444.4 0.0 3.5e-133 444.1 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Esterase PF00756.20 OWF45149.1 - 0.028 14.1 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 OWF45149.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OWF45149.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) La PF05383.17 OWF45150.1 - 1.7e-22 79.2 0.3 9.2e-22 76.9 0.1 2.4 2 0 0 2 2 2 1 La domain COesterase PF00135.28 OWF45151.1 - 3.4e-142 474.9 0.0 4e-142 474.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF45151.1 - 1.1e-08 35.2 0.6 3.4e-08 33.6 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OWF45151.1 - 0.0078 15.1 0.2 0.034 13.0 0.2 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OWF45151.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4945 PF16303.5 OWF45151.1 - 0.18 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) Gln-synt_N PF03951.19 OWF45152.1 - 7.1 6.4 12.7 5.7 6.7 0.2 4.0 2 2 2 4 4 4 0 Glutamine synthetase, beta-Grasp domain Pkinase PF00069.25 OWF45153.1 - 7.2e-69 232.1 0.0 1.3e-68 231.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF45153.1 - 6e-35 120.8 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase BTB PF00651.31 OWF45154.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 BTB/POZ domain NHL PF01436.21 OWF45155.1 - 0.00044 20.1 2.4 2.6 8.2 0.0 5.0 5 0 0 5 5 5 1 NHL repeat GLEYA PF10528.9 OWF45155.1 - 0.011 16.1 0.2 8.7 6.8 0.0 3.5 3 0 0 3 3 3 0 GLEYA domain DUF3659 PF12396.8 OWF45155.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Peptidase_C37 PF05416.12 OWF45155.1 - 1.1 7.7 10.6 1.7 7.1 10.6 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase zf_Hakai PF18408.1 OWF45155.1 - 8.5 6.2 6.4 0.39 10.5 0.2 2.0 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain C1q PF00386.21 OWF45156.1 - 2.2e-23 82.9 0.5 2.6e-23 82.6 0.5 1.1 1 0 0 1 1 1 1 C1q domain LTD PF00932.19 OWF45156.1 - 0.0056 17.0 0.1 0.0085 16.4 0.1 1.4 1 0 0 1 1 1 1 Lamin Tail Domain AXE1 PF05448.12 OWF45156.1 - 0.12 11.0 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) C1q PF00386.21 OWF45157.1 - 5.9e-17 62.1 0.7 7.2e-17 61.8 0.7 1.1 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 OWF45158.1 - 2.4e-20 73.0 0.8 3e-20 72.7 0.8 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF45158.1 - 0.035 14.0 1.3 0.043 13.7 1.3 1.1 1 0 0 1 1 1 0 BclA C-terminal domain SNF PF00209.18 OWF45159.1 - 1e-190 634.9 40.4 1.2e-190 634.7 40.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4773 PF15998.5 OWF45160.1 - 4e-13 49.9 5.3 5.6e-13 49.5 5.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) DUF4773 PF15998.5 OWF45161.1 - 6.5e-16 58.9 6.7 8.4e-16 58.6 6.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) DUF1387 PF07139.11 OWF45162.1 - 8.5e-63 213.0 3.0 1.5e-62 212.1 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) SPX PF03105.19 OWF45162.1 - 0.0014 18.6 4.3 0.0018 18.3 4.3 1.3 1 0 0 1 1 1 1 SPX domain UBA_4 PF14555.6 OWF45162.1 - 0.013 15.3 0.0 0.077 12.8 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain CUE PF02845.16 OWF45162.1 - 0.043 13.5 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 CUE domain HBS1_N PF08938.10 OWF45162.1 - 0.066 13.5 0.2 0.066 13.5 0.2 2.3 3 0 0 3 3 3 0 HBS1 N-terminus YojJ PF10372.9 OWF45162.1 - 0.072 13.2 0.3 0.25 11.5 0.2 2.0 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Apt1 PF10351.9 OWF45162.1 - 0.85 8.4 10.9 1.3 7.8 10.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC24 PF15669.5 OWF45162.1 - 2.1 8.2 9.2 1.7 8.5 6.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Ank_4 PF13637.6 OWF45163.1 - 1.5e-24 86.0 1.1 7.6e-08 32.8 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF45163.1 - 1.4e-22 80.0 0.0 4.6e-14 52.8 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF45163.1 - 9.4e-22 74.8 0.1 0.00066 19.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OWF45163.1 - 6.4e-19 67.5 0.0 3.5e-05 24.0 0.0 4.7 4 1 1 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF45163.1 - 7e-15 54.9 0.1 2.8e-05 24.3 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) zf-C2H2_6 PF13912.6 OWF45164.1 - 8.6e-14 51.1 30.2 0.00088 19.2 0.2 7.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF45164.1 - 1.8e-10 40.7 38.4 0.00015 22.0 0.8 7.4 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF45164.1 - 4.3e-10 39.6 41.4 0.0051 17.6 0.7 7.9 8 0 0 8 8 7 5 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OWF45164.1 - 5e-07 30.4 10.7 0.84 10.3 0.2 6.1 4 1 2 6 6 6 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 OWF45164.1 - 3.2e-05 24.1 36.1 0.17 12.2 0.3 7.2 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding C1_2 PF03107.16 OWF45164.1 - 0.0027 18.0 32.6 4.1 7.8 0.1 7.0 5 2 1 6 6 6 1 C1 domain CpXC PF14353.6 OWF45164.1 - 0.0037 17.3 0.9 0.056 13.5 0.1 4.1 3 3 1 4 4 3 2 CpXC protein DUF2256 PF10013.9 OWF45164.1 - 0.017 15.3 19.8 0.43 10.7 0.4 6.4 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.6 OWF45164.1 - 0.06 13.3 0.4 0.06 13.3 0.4 5.8 8 0 0 8 8 8 0 Probable zinc-ribbon domain ZZ PF00569.17 OWF45164.1 - 0.11 12.3 33.7 8.7 6.2 3.9 7.2 6 1 1 7 7 7 0 Zinc finger, ZZ type zf-met PF12874.7 OWF45164.1 - 0.21 12.0 38.3 0.47 10.9 0.6 7.6 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OWF45164.1 - 0.71 10.4 0.0 0.71 10.4 0.0 8.8 8 2 0 8 8 8 0 Zinc-finger double domain ADK_lid PF05191.14 OWF45164.1 - 2.6 8.1 18.6 5.4 7.1 0.0 5.6 6 1 0 6 6 6 0 Adenylate kinase, active site lid TauD PF02668.16 OWF45165.1 - 2.2e-20 73.6 0.0 7.7e-20 71.8 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lectin_C PF00059.21 OWF45165.1 - 8.2e-07 29.7 0.2 2.1e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 Lectin C-type domain Lipase_GDSL_2 PF13472.6 OWF45166.1 - 8e-09 36.1 0.0 9.5e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AviRa PF11599.8 OWF45166.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PAF-AH_p_II PF03403.13 OWF45167.1 - 2.6e-104 348.8 0.1 7.7e-103 343.9 0.1 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OWF45167.1 - 1.3e-05 24.6 0.0 0.078 12.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OWF45167.1 - 1.3e-05 24.2 0.0 0.0025 16.8 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 OWF45167.1 - 0.00038 20.2 0.0 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 OWF45167.1 - 0.00041 19.5 0.0 0.16 11.0 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase DLH PF01738.18 OWF45167.1 - 0.0013 18.3 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 OWF45167.1 - 0.0018 17.0 0.2 1 8.0 0.0 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OWF45167.1 - 0.0091 15.5 0.0 0.045 13.2 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OWF45167.1 - 0.024 15.2 0.0 0.053 14.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 OWF45167.1 - 0.042 13.5 0.1 3.4 7.2 0.0 2.7 1 1 2 3 3 3 0 Putative esterase EGF_2 PF07974.13 OWF45168.1 - 0.46 10.9 66.4 0.43 11.0 9.4 4.3 3 1 0 3 3 3 0 EGF-like domain Tmemb_cc2 PF10267.9 OWF45169.1 - 2.9e-136 454.8 12.0 4.8e-136 454.1 12.0 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Prominin PF05478.11 OWF45169.1 - 0.0012 16.9 11.2 0.0023 16.0 2.6 2.1 2 0 0 2 2 2 2 Prominin Spc7 PF08317.11 OWF45169.1 - 0.0027 16.6 19.1 0.047 12.6 7.0 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 OWF45169.1 - 0.0031 17.1 12.5 0.11 12.0 1.8 2.2 2 0 0 2 2 2 2 Exonuclease VII, large subunit DUF16 PF01519.16 OWF45169.1 - 0.005 17.3 14.3 0.23 12.0 3.3 2.8 2 0 0 2 2 2 2 Protein of unknown function DUF16 DUF2383 PF09537.10 OWF45169.1 - 0.025 14.9 5.1 1.6 9.1 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) MetOD2 PF18548.1 OWF45169.1 - 0.22 11.7 14.4 0.092 12.9 5.8 2.9 2 0 0 2 2 2 0 Metanogen output domain 2 Calcyon PF06387.11 OWF45169.1 - 0.26 11.3 2.7 0.37 10.8 0.6 2.3 2 0 0 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) NPV_P10 PF05531.12 OWF45169.1 - 0.33 11.5 7.4 1.7 9.1 1.1 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 OWF45169.1 - 1.1 8.7 23.7 2.5 7.5 5.1 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 OmpH PF03938.14 OWF45169.1 - 1.5 9.2 21.8 2.2 8.6 5.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Phage_GPO PF05929.11 OWF45169.1 - 1.8 8.1 12.2 1.9 8.0 2.7 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ApoLp-III PF07464.11 OWF45169.1 - 2.1 8.5 18.7 9 6.4 1.5 3.5 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Jnk-SapK_ap_N PF09744.9 OWF45169.1 - 9.5 6.4 25.4 7.3 6.8 7.6 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Guanylate_cyc PF00211.20 OWF45170.1 - 2.2e-27 95.9 0.1 7.9e-26 90.8 0.0 2.7 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 OWF45170.1 - 4.7e-27 95.9 0.0 6.7e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 OWF45170.1 - 7.6e-05 22.2 0.4 0.00013 21.5 0.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated DUF5389 PF17364.2 OWF45170.1 - 0.023 14.7 0.2 0.062 13.3 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5389) FlgT_N PF16548.5 OWF45170.1 - 0.05 14.2 0.1 3.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain 7TM_GPCR_Srw PF10324.9 OWF45171.1 - 3.7e-28 98.7 22.0 6.2e-28 98.0 22.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF45171.1 - 1.5e-25 90.0 17.4 2e-25 89.6 17.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF45171.1 - 0.0021 17.8 26.1 0.0021 17.8 26.1 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3262 PF11660.8 OWF45171.1 - 0.37 11.2 11.4 1.9 8.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Serpentine_r_xa PF03383.15 OWF45171.1 - 6.1 6.8 13.9 0.037 14.0 3.9 2.4 3 0 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa MIP PF00230.20 OWF45172.1 - 2.7e-64 217.0 10.8 3.2e-64 216.8 10.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Aminotran_5 PF00266.19 OWF45173.1 - 4e-07 29.3 0.0 1.6e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V RDD PF06271.12 OWF45174.1 - 2.4e-10 40.8 2.4 4.4e-09 36.7 2.4 2.2 1 1 0 1 1 1 1 RDD family DUF543 PF04418.12 OWF45174.1 - 0.27 11.3 1.5 3.2 7.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF543) TLD PF07534.16 OWF45175.1 - 4.4e-33 114.4 1.5 9.5e-33 113.4 1.5 1.6 1 0 0 1 1 1 1 TLD LysM PF01476.20 OWF45175.1 - 7e-09 35.6 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain zf-C2H2 PF00096.26 OWF45176.1 - 2.3e-37 125.4 180.6 4.5e-06 26.8 1.3 20.6 20 0 0 20 20 20 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF45176.1 - 9e-30 100.8 174.2 0.00061 20.4 0.7 20.8 21 0 0 21 21 21 16 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF45176.1 - 1.9e-07 31.2 22.7 6.3e-05 23.2 2.1 19.5 22 0 0 22 22 22 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF45176.1 - 0.0056 16.9 137.5 0.44 10.9 0.7 17.7 18 1 0 18 18 18 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF45176.1 - 0.013 15.5 1.3 0.013 15.5 1.3 18.8 20 0 0 20 20 20 0 C2H2-type zinc finger BolA PF01722.18 OWF45176.1 - 0.017 15.4 8.6 1.2 9.5 0.0 5.1 5 1 0 5 5 5 0 BolA-like protein SET PF00856.28 OWF45176.1 - 0.055 13.8 0.0 0.055 13.8 0.0 4.3 3 1 0 3 3 3 0 SET domain DHHC PF01529.20 OWF45177.1 - 2.5e-28 98.8 12.0 2.5e-28 98.8 12.0 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Tail_VII PF17091.5 OWF45178.1 - 0.051 13.5 2.9 0.14 12.0 2.9 1.8 1 0 0 1 1 1 0 Inovirus G7P protein TMEM173 PF15009.6 OWF45178.1 - 0.32 10.1 2.6 0.53 9.4 2.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 173 TssN PF17555.2 OWF45178.1 - 1.5 8.1 8.5 2.4 7.5 8.5 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4972 PF16342.5 OWF45178.1 - 2.1 8.1 4.1 0.49 10.1 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) DUF5527 PF17665.1 OWF45178.1 - 2.7 7.5 5.5 0.69 9.5 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5527) DUF2427 PF10348.9 OWF45178.1 - 3.1 7.6 8.0 2.8 7.8 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) 7tm_1 PF00001.21 OWF45179.1 - 1.8e-20 73.4 10.7 2.3e-20 73.0 10.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4149 PF13664.6 OWF45179.1 - 1.1 9.6 11.5 1.3 9.4 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) DUF2207 PF09972.9 OWF45179.1 - 1.8 7.2 6.9 21 3.7 4.7 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Spin-Ssty PF02513.17 OWF45180.1 - 0.015 15.1 0.7 0.042 13.6 0.7 1.9 1 1 0 1 1 1 0 Spin/Ssty Family NPH3 PF03000.14 OWF45180.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 NPH3 family Agenet PF05641.12 OWF45180.1 - 0.14 12.7 0.2 0.27 11.7 0.2 1.5 1 0 0 1 1 1 0 Agenet domain Mucin PF01456.17 OWF45180.1 - 0.21 11.6 6.1 0.29 11.1 6.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Arch_flagellin PF01917.16 OWF45180.1 - 0.41 10.8 2.6 0.54 10.4 2.6 1.4 1 1 0 1 1 1 0 Archaebacterial flagellin 7tm_1 PF00001.21 OWF45181.1 - 1.3e-19 70.6 16.9 1.7e-19 70.2 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF45181.1 - 3.1e-09 36.5 21.5 5.6e-08 32.4 21.5 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF45181.1 - 0.14 11.7 26.5 0.0087 15.7 8.8 2.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx PfaD_N PF18328.1 OWF45183.1 - 0.029 14.3 0.1 24 4.9 0.0 3.5 2 1 3 5 5 5 0 Fatty acid synthase subunit PfaD N-terminal domain GP70 PF17429.2 OWF45183.1 - 0.097 12.5 0.2 36 4.3 0.0 3.3 3 1 2 5 5 5 0 Gene product 70 PfaD_N PF18328.1 OWF45184.1 - 0.0035 17.2 0.1 31 4.6 0.0 3.5 2 1 2 4 4 4 1 Fatty acid synthase subunit PfaD N-terminal domain GP70 PF17429.2 OWF45184.1 - 0.022 14.5 0.0 21 5.0 0.0 3.2 3 1 1 4 4 4 0 Gene product 70 NIDO PF06119.14 OWF45184.1 - 0.48 11.4 2.5 48 5.0 0.7 3.1 2 1 0 2 2 2 0 Nidogen-like FAM24 PF15193.6 OWF45184.1 - 0.55 11.0 12.5 13 6.7 0.3 3.9 1 1 4 5 5 5 0 FAM24 family Gly_transf_sug PF04488.15 OWF45185.1 - 1.7e-10 41.4 0.1 5.9e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OWF45185.1 - 0.0058 16.0 0.1 0.025 13.9 0.1 1.8 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 OWF45185.1 - 0.015 14.7 0.5 0.032 13.6 0.4 1.7 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein EF-hand_7 PF13499.6 OWF45186.1 - 9.8e-18 64.4 8.9 5.4e-11 42.8 0.8 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF45186.1 - 1.5e-16 58.6 3.5 4.8e-06 25.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF45186.1 - 1.1e-14 53.0 8.2 2.8e-07 29.9 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OWF45186.1 - 2.9e-12 46.2 5.7 0.00049 19.9 1.6 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF45186.1 - 1.5e-09 36.9 9.5 0.00066 19.1 2.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 OWF45186.1 - 0.0038 17.2 1.3 0.41 10.6 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF45186.1 - 0.0041 17.4 2.3 0.41 11.0 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 OWF45186.1 - 0.069 13.1 1.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Caleosin related protein PHB_acc_N PF07879.11 OWF45186.1 - 0.11 12.6 0.8 0.37 10.9 0.7 1.9 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain EF-hand_7 PF13499.6 OWF45188.1 - 8.6e-23 80.6 3.0 3.2e-11 43.5 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF45188.1 - 1.8e-22 77.1 7.2 2.6e-05 23.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF45188.1 - 1.2e-18 65.4 4.9 9.1e-05 22.1 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF45188.1 - 1.1e-16 59.5 6.0 6.3e-06 25.4 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF45188.1 - 8.2e-12 44.8 7.0 0.002 17.9 0.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF45188.1 - 8.8e-06 26.0 0.2 0.0002 21.6 0.0 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OWF45188.1 - 9.1e-06 25.9 0.6 0.0002 21.6 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_11 PF08976.11 OWF45188.1 - 0.00044 21.1 0.0 0.00087 20.1 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain Pup_ligase PF03136.15 OWF45188.1 - 0.0098 15.0 0.0 0.011 14.8 0.0 1.0 1 0 0 1 1 1 1 Pup-ligase protein EF-hand_14 PF17959.1 OWF45188.1 - 0.026 14.9 0.1 8.4 6.8 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 OWF45188.1 - 1 9.6 4.9 5.6 7.2 0.5 3.4 3 1 1 4 4 4 0 Dockerin type I domain HEV_ORF1 PF02444.16 OWF45189.1 - 0.024 15.2 0.9 0.024 15.2 0.9 1.7 1 1 1 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) EF-hand_7 PF13499.6 OWF45190.1 - 4.4e-14 52.7 0.0 5.2e-06 26.8 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF45190.1 - 1.4e-12 46.2 0.0 0.014 14.9 0.0 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OWF45190.1 - 2.3e-12 45.8 0.0 0.003 17.4 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF45190.1 - 2.3e-11 42.6 0.2 0.00023 20.5 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF45190.1 - 1.2e-08 34.7 0.1 6.3e-06 26.0 0.0 3.1 3 1 1 4 4 4 2 EF-hand domain pair Cornifin PF02389.15 OWF45191.1 - 3.6e-06 27.2 46.5 0.0016 18.6 19.0 3.2 1 1 2 3 3 3 3 Cornifin (SPRR) family DUF5385 PF17359.2 OWF45192.1 - 0.021 14.4 0.1 0.021 14.4 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF5056 PF16479.5 OWF45192.1 - 0.042 14.1 0.1 0.079 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) MORN PF02493.20 OWF45193.1 - 1.2e-20 72.1 22.5 5.9e-08 32.1 2.3 6.2 6 0 0 6 6 6 4 MORN repeat 2-oxoacid_dh PF00198.23 OWF45194.1 - 7.7e-79 264.4 0.0 1.1e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OWF45194.1 - 9e-16 57.5 0.1 2e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 OWF45194.1 - 1.9e-12 47.3 0.2 1.9e-12 47.3 0.2 2.0 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OWF45194.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like DEC-1_N PF04625.13 OWF45194.1 - 1.9 7.4 12.0 3.1 6.7 12.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ubiquitin_4 PF18036.1 OWF45195.1 - 1.7e-12 47.2 0.3 2.8e-12 46.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain SdiA-regulated PF06977.11 OWF45195.1 - 0.017 14.4 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 SdiA-regulated Lyase_8_C PF02884.17 OWF45195.1 - 0.04 14.4 0.1 0.087 13.3 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain TFIIS_C PF01096.18 OWF45196.1 - 2.2e-19 69.0 7.5 2.2e-19 69.0 7.5 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OWF45196.1 - 1.8e-07 30.9 4.0 1.8e-07 30.9 4.0 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 OWF45196.1 - 0.0013 18.4 1.0 0.0027 17.3 1.0 1.6 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain zf-SAP30 PF13866.6 OWF45196.1 - 0.012 15.8 0.3 0.057 13.5 0.1 1.9 2 0 0 2 2 2 0 SAP30 zinc-finger zf-GRF PF06839.12 OWF45196.1 - 0.012 15.7 1.6 0.012 15.7 1.6 2.5 2 1 1 3 3 3 0 GRF zinc finger Opy2 PF09463.10 OWF45196.1 - 0.4 11.1 0.1 0.4 11.1 0.1 3.5 3 1 0 3 3 3 0 Opy2 protein PhnA_Zn_Ribbon PF08274.12 OWF45196.1 - 3.5 7.7 0.0 3.5 7.7 0.0 3.3 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Far-17a_AIG1 PF04750.14 OWF45197.1 - 7.8e-51 172.3 8.0 9.6e-51 172.0 8.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein EF-hand_7 PF13499.6 OWF45198.1 - 2.2e-35 120.9 1.2 9.8e-18 64.4 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF45198.1 - 4.2e-33 110.4 3.0 1.2e-08 33.8 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF45198.1 - 8.8e-29 96.9 0.8 2.3e-07 30.2 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF45198.1 - 3.1e-23 80.2 0.6 4.5e-07 29.1 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF45198.1 - 4.9e-22 77.5 5.2 3.1e-08 33.3 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF45198.1 - 3.6e-09 36.9 0.0 0.0004 20.7 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF45198.1 - 2.5e-06 27.4 0.2 0.0008 19.3 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 OWF45198.1 - 1.1e-05 25.2 0.9 0.17 11.8 0.2 3.8 3 1 1 4 4 4 2 EF hand p25-alpha PF05517.12 OWF45198.1 - 0.0028 17.9 1.4 2.3 8.4 0.0 2.9 1 1 1 3 3 3 2 p25-alpha Dockerin_1 PF00404.18 OWF45198.1 - 0.012 15.8 0.1 0.21 11.8 0.0 2.5 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 OWF45198.1 - 0.033 14.5 0.4 17 5.9 0.0 3.2 1 1 1 3 3 3 0 EF-hand domain DUF3911 PF13050.6 OWF45198.1 - 0.044 13.9 1.1 15 5.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3911) Caleosin PF05042.13 OWF45198.1 - 0.046 13.6 0.3 15 5.5 0.1 3.5 1 1 0 3 3 3 0 Caleosin related protein DUF1722 PF08349.11 OWF45198.1 - 0.14 12.5 0.2 17 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PMBR PF09373.10 OWF45198.1 - 0.25 11.6 0.4 25 5.3 0.0 3.5 5 0 0 5 5 5 0 Pseudomurein-binding repeat FKBP_C PF00254.28 OWF45201.1 - 2.5e-17 63.0 0.0 3.5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EphA2_TM PF14575.6 OWF45202.1 - 0.00049 20.9 2.0 0.0011 19.8 0.0 2.6 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF45202.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 2.8 3 1 0 3 3 3 1 TMEM154 protein family Orthoreo_P10 PF07204.11 OWF45202.1 - 0.0072 16.3 1.1 0.02 14.8 1.1 1.7 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Cortexin PF11057.8 OWF45202.1 - 0.019 14.8 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Cortexin of kidney Cadherin_C_2 PF16492.5 OWF45202.1 - 0.14 12.9 0.0 0.56 11.0 0.0 2.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Protocadherin PF08374.11 OWF45202.1 - 0.2 11.6 7.7 0.023 14.7 2.1 2.3 2 1 0 2 2 2 0 Protocadherin FAM176 PF14851.6 OWF45202.1 - 0.66 9.6 0.0 0.66 9.6 0.0 3.2 2 1 0 2 2 2 0 FAM176 family Adeno_E3_CR2 PF02439.15 OWF45202.1 - 1.4 8.8 10.9 3 7.7 10.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Viral_RdRp_C PF17501.2 OWF45203.1 - 0.063 13.7 0.0 0.19 12.2 0.0 1.7 1 1 1 2 2 2 0 Viral RNA-directed RNA polymerase C1q PF00386.21 OWF45204.1 - 3.4e-22 79.0 0.0 6.6e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 C1q domain Herpes_UL6 PF01763.16 OWF45204.1 - 0.045 12.3 1.1 0.061 11.8 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like ECH_1 PF00378.20 OWF45204.1 - 0.15 11.4 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase PCO_ADO PF07847.12 OWF45205.1 - 0.0063 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 OWF45205.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I CDO_I PF05995.12 OWF45206.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OWF45206.1 - 0.0099 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO RITA PF17066.5 OWF45207.1 - 2.7e-09 37.0 9.5 5e-08 32.9 7.9 2.9 1 1 0 1 1 1 1 RBPJ-interacting and tubulin associated protein Secretogranin_V PF05281.11 OWF45207.1 - 0.11 12.2 0.3 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Peptidase_C98 PF15499.6 OWF45208.1 - 2.7e-80 269.8 7.1 7.2e-79 265.1 7.1 2.3 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Astacin PF01400.24 OWF45210.1 - 2.9e-53 180.3 0.3 5.9e-53 179.3 0.0 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) TSP_1 PF00090.19 OWF45210.1 - 4e-06 26.9 10.9 4e-06 26.9 10.9 3.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain CUB PF00431.20 OWF45210.1 - 0.00075 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 CUB domain Reprolysin_4 PF13583.6 OWF45210.1 - 0.063 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF45210.1 - 0.15 11.9 0.4 5.7 6.8 0.4 2.2 1 1 1 2 2 2 0 Matrixin MAM PF00629.23 OWF45211.1 - 2.9e-83 277.6 0.8 1.3e-31 109.7 0.0 3.4 3 0 0 3 3 3 3 MAM domain, meprin/A5/mu Astacin PF01400.24 OWF45211.1 - 1.7e-39 135.4 1.5 4.1e-39 134.2 1.5 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 OWF45211.1 - 1e-10 41.9 0.0 2.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 CUB domain EGF PF00008.27 OWF45211.1 - 7.8e-08 32.5 5.5 7.8e-08 32.5 5.5 4.2 3 1 1 4 4 4 2 EGF-like domain rve PF00665.26 OWF45213.1 - 0.032 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain MFS_1 PF07690.16 OWF45214.1 - 3.4e-50 170.9 30.7 1.2e-49 169.2 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OWF45215.1 - 2.6e-55 187.8 26.5 2.4e-52 178.0 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RE_BsaWI PF18643.1 OWF45216.1 - 0.028 14.3 0.9 0.074 13.0 0.9 1.7 1 0 0 1 1 1 0 BsaWI restriction endonuclease type 2 UIM PF02809.20 OWF45216.1 - 0.066 13.2 0.3 0.27 11.3 0.3 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF769 PF05590.11 OWF45217.1 - 0.79 9.1 3.6 63 2.9 0.3 3.8 1 1 4 5 5 5 0 Xylella fastidiosa protein of unknown function (DUF769) zf-C2H2_12 PF18658.1 OWF45217.1 - 1.3 8.6 5.2 31 4.2 0.1 4.0 2 1 2 4 4 4 0 Zinc-finger C2H2-type Ribosomal_S17_N PF16205.5 OWF45217.1 - 7.1 7.1 12.6 1.1e+02 3.3 0.0 5.9 8 0 0 8 8 8 0 Ribosomal_S17 N-terminal Reprolysin_5 PF13688.6 OWF45218.1 - 2.6e-29 102.8 1.9 2.6e-29 102.8 1.9 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OWF45218.1 - 8.1e-25 87.9 0.6 1.8e-24 86.7 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF45218.1 - 7.4e-18 65.3 3.0 9.2e-18 64.9 0.3 2.6 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF45218.1 - 2e-11 43.9 1.3 2e-11 43.9 1.3 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OWF45218.1 - 1.2e-09 38.8 27.8 1.2e-09 38.8 27.8 3.9 1 1 1 2 2 2 1 Disintegrin 7kD_DNA_binding PF02294.18 OWF45218.1 - 4.6e-06 26.6 5.9 36 4.5 0.0 6.9 1 1 6 9 9 9 0 7kD DNA-binding domain Pep_M12B_propep PF01562.19 OWF45218.1 - 8.3e-06 26.1 0.2 1.8e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 OWF45218.1 - 1.8e-05 24.7 0.7 4.2e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Imm31 PF15591.6 OWF45218.1 - 2.6 7.9 17.0 41 4.1 0.0 6.8 2 1 3 7 7 7 0 Immunity protein 31 Rhabdo_glycop PF00974.18 OWF45219.1 - 0.04 12.4 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF5560 PF17715.1 OWF45219.1 - 1.4 8.4 6.8 1.2 8.5 5.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5560) adh_short PF00106.25 OWF45220.1 - 8.7e-40 136.3 0.0 1.1e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF45220.1 - 1.5e-20 73.8 0.0 1.7e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF45220.1 - 5.9e-10 39.3 0.0 8.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OWF45220.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fasciclin PF02469.22 OWF45221.1 - 2.7e-71 237.8 0.2 2.1e-34 118.5 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF1930 PF09122.10 OWF45221.1 - 0.17 11.9 1.2 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1930) Fasciclin PF02469.22 OWF45222.1 - 2.4e-69 231.5 0.0 1.2e-33 116.1 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF1930 PF09122.10 OWF45222.1 - 0.36 10.8 2.2 0.4 10.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1930) CNH PF00780.22 OWF45223.1 - 1e-55 189.3 0.0 1.3e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 CNH domain Copine PF07002.16 OWF45223.1 - 0.051 13.0 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Copine Pkinase PF00069.25 OWF45224.1 - 1.3e-61 208.3 0.0 1.8e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF45224.1 - 4.5e-47 160.5 0.0 6e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF45224.1 - 8e-06 24.9 0.4 0.00018 20.4 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 OWF45224.1 - 0.004 16.5 0.3 0.014 14.7 0.0 2.0 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 OWF45224.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OWF45224.1 - 0.0065 16.1 0.1 0.27 10.8 0.0 2.5 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 FAM176 PF14851.6 OWF45224.1 - 6.8 6.4 10.7 1.8 8.2 0.3 2.7 2 1 0 2 2 2 0 FAM176 family Opiods_neuropep PF01160.18 OWF45225.1 - 0.055 13.6 0.5 88 3.3 0.0 3.4 1 1 5 6 6 6 0 Vertebrate endogenous opioids neuropeptide RAG1_imp_bd PF12560.8 OWF45226.1 - 0.016 14.7 0.3 0.024 14.2 0.3 1.2 1 0 0 1 1 1 0 RAG1 importin binding GST_N_4 PF17172.4 OWF45227.1 - 2.6e-18 66.6 0.0 4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF45227.1 - 2.8e-07 30.2 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF45227.1 - 0.023 15.1 0.0 0.073 13.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF45227.1 - 0.043 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TMEM154 PF15102.6 OWF45228.1 - 0.0016 18.4 3.4 0.0016 18.4 3.4 1.7 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 OWF45228.1 - 0.0018 19.1 0.2 0.0084 17.0 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OWF45228.1 - 0.002 17.5 8.5 0.002 17.5 8.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MIG-14_Wnt-bd PF06664.12 OWF45228.1 - 0.013 14.8 0.3 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion YajC PF02699.15 OWF45228.1 - 0.032 14.1 0.3 0.078 12.9 0.3 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit PIRT PF15099.6 OWF45228.1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4381 PF14316.6 OWF45228.1 - 0.17 12.1 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) BatA PF07584.11 OWF45228.1 - 0.21 12.0 0.1 0.21 12.0 0.1 1.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal CcmD PF04995.14 OWF45228.1 - 2.5 8.2 5.2 5.2 7.2 5.2 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PMP1_2 PF08114.11 OWF45228.1 - 7.4 6.4 8.2 0.46 10.3 2.9 1.8 2 0 0 2 2 2 0 ATPase proteolipid family DUF1491 PF07372.12 OWF45229.1 - 2.6e-11 43.8 44.0 0.22 11.9 1.5 10.3 1 1 8 9 9 9 9 Protein of unknown function (DUF1491) LRR_8 PF13855.6 OWF45230.1 - 2.4e-34 116.9 35.8 3.5e-13 49.1 10.9 8.4 8 1 0 9 9 9 6 Leucine rich repeat TIR PF01582.20 OWF45230.1 - 1.7e-14 54.0 0.1 2.8e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF45230.1 - 4.7e-14 53.0 0.0 9.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF45230.1 - 8.3e-11 41.9 45.1 0.024 15.0 1.8 10.1 6 4 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF45230.1 - 1.5e-07 31.4 3.0 4.9e-05 23.3 0.1 3.7 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF45230.1 - 2.6e-06 27.0 7.5 6.5e-05 22.5 1.4 3.1 3 0 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 OWF45230.1 - 0.0045 16.9 30.0 3.8 7.8 0.0 9.8 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.33 OWF45230.1 - 0.021 15.3 34.9 26 5.9 0.0 11.7 12 1 1 13 13 13 0 Leucine Rich Repeat LRRNT PF01462.18 OWF45230.1 - 1.2 8.9 3.2 3.4 7.4 0.5 2.7 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain SSF PF00474.17 OWF45231.1 - 6.7e-15 54.9 6.3 8.9e-15 54.5 6.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family PC4 PF02229.16 OWF45232.1 - 1.6e-22 78.8 0.6 1.6e-11 43.7 0.1 2.4 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) TNF PF00229.18 OWF45233.1 - 5.8e-22 78.0 0.8 8.9e-22 77.4 0.8 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF45233.1 - 0.0092 16.2 0.1 0.025 14.8 0.1 1.7 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF45233.1 - 0.58 10.1 3.3 6.8 6.6 3.3 2.2 1 1 0 1 1 1 0 BclA C-terminal domain MITF_TFEB_C_3_N PF15951.5 OWF45234.1 - 1.4e-22 81.0 2.3 1.4e-22 81.0 2.3 2.8 2 1 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus HLH PF00010.26 OWF45234.1 - 2.2e-15 56.3 2.0 5.8e-15 55.0 2.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HDNR PF15115.6 OWF45235.1 - 2.3e-25 89.8 7.1 3.5e-25 89.2 7.1 1.3 1 0 0 1 1 1 1 Domain of unknown function with conserved HDNR motif Phage_int_SAM_6 PF18644.1 OWF45236.1 - 0.02 14.9 1.1 0.02 14.9 1.1 3.8 3 1 1 4 4 4 0 Phage integrase SAM-like domain Mad3_BUB1_I_2 PF17014.5 OWF45236.1 - 0.47 10.6 5.6 0.24 11.5 1.0 2.6 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein G-patch_2 PF12656.7 OWF45237.1 - 1e-21 76.8 1.5 3.6e-21 75.0 0.1 2.8 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 OWF45237.1 - 4.2e-10 39.3 1.1 9.7e-10 38.2 1.1 1.6 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 OWF45237.1 - 0.0073 16.2 0.0 0.3 11.1 0.0 3.1 3 0 0 3 3 3 1 KOW motif KN17_SH3 PF18131.1 OWF45237.1 - 0.0095 16.0 0.0 0.05 13.7 0.0 2.3 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain HDA2-3 PF11496.8 OWF45238.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DUF4549 PF15082.6 OWF45239.1 - 7.2e-56 187.9 2.5 7.2e-56 187.9 2.5 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4549) CarD_CdnL_TRCF PF02559.16 OWF45239.1 - 0.014 16.0 3.4 0.087 13.5 3.4 2.4 1 0 0 1 1 1 0 CarD-like/TRCF domain Sec23_helical PF04815.15 OWF45239.1 - 0.29 11.0 2.8 1.2 9.0 1.0 2.7 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Baculo_PEP_C PF04513.12 OWF45239.1 - 2 8.5 8.2 2 8.5 0.0 3.5 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MspA PF09203.11 OWF45241.1 - 0.11 12.4 9.7 0.75 9.6 2.4 2.1 1 1 1 2 2 2 0 MspA Keratin_2_head PF16208.5 OWF45241.1 - 0.16 12.1 15.9 1.4 9.0 3.8 2.3 1 1 1 2 2 2 0 Keratin type II head KRTAP PF11759.8 OWF45241.1 - 0.25 11.9 12.1 8e+02 0.7 12.1 2.9 1 1 0 1 1 1 0 Keratin-associated matrix Plasmodium_HRP PF05403.11 OWF45241.1 - 0.52 10.1 7.2 1.4 8.6 7.2 1.7 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF2810 PF10928.8 OWF45241.1 - 2.9 8.0 7.7 56 3.8 0.6 4.5 2 2 3 5 5 5 0 Protein of unknown function (DUF2810) KRTAP PF11759.8 OWF45243.1 - 0.001 19.6 43.8 1.8e+04 -21.4 43.8 4.9 1 1 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 OWF45243.1 - 0.82 9.8 46.7 16 5.6 11.2 4.2 1 1 2 3 3 3 0 Keratin type II head SOUL PF04832.12 OWF45244.1 - 4.7e-48 163.5 0.1 5.5e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein SOUL PF04832.12 OWF45245.1 - 4.6e-43 147.3 0.2 5.4e-43 147.1 0.2 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein ECH_1 PF00378.20 OWF45246.1 - 6.6e-56 189.4 0.0 7.4e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF45246.1 - 1.2e-27 97.3 0.2 7.6e-26 91.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PDZ PF00595.24 OWF45247.1 - 1.5e-22 79.7 0.1 3.2e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OWF45247.1 - 6.5e-21 73.9 0.2 2.7e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OWF45247.1 - 3.3e-18 65.8 0.4 3.4e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 OWF45247.1 - 0.0026 17.7 0.1 0.73 9.8 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain CCM2_C PF16545.5 OWF45247.1 - 0.11 13.1 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology TMEM132D_C PF15706.5 OWF45248.1 - 0.58 10.0 0.0 0.58 10.0 0.0 2.8 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term GPI2 PF06432.11 OWF45248.1 - 3.4 7.1 9.7 3.9 6.8 3.8 2.5 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase PALP PF00291.25 OWF45249.1 - 2.5e-65 220.8 0.2 3.1e-65 220.5 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PDZ PF00595.24 OWF45250.1 - 2.8e-09 37.2 0.0 3.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OWF45250.1 - 5.4e-06 26.1 0.0 2.3e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Death PF00531.22 OWF45250.1 - 0.00062 19.9 0.6 0.002 18.3 0.6 1.9 2 0 0 2 2 2 1 Death domain PDZ_2 PF13180.6 OWF45250.1 - 0.034 14.5 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 PDZ domain Rad52_Rad22 PF04098.15 OWF45252.1 - 4.1e-49 166.4 0.0 7.3e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UCH PF00443.29 OWF45254.1 - 3.7e-47 161.0 0.0 5.9e-46 157.0 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF45254.1 - 1.7e-10 41.1 7.1 4e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ORC_WH_C PF18137.1 OWF45254.1 - 0.024 14.7 0.7 2.1 8.4 0.2 3.2 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Peptidase_C98 PF15499.6 OWF45254.1 - 7.8 5.9 11.3 2.2 7.7 0.3 3.0 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Cast PF10174.9 OWF45255.1 - 2.9e-145 485.4 163.3 1.9e-143 479.4 163.3 2.7 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone UPF0242 PF06785.11 OWF45255.1 - 0.0029 17.7 16.9 0.0029 17.7 16.9 8.8 2 2 6 9 9 9 3 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OWF45255.1 - 0.027 14.9 157.6 0.35 11.3 16.7 7.7 1 1 6 8 8 8 0 Fez1 ERM PF00769.19 OWF45255.1 - 0.093 12.5 166.8 0.011 15.6 26.6 6.6 1 1 5 6 6 6 0 Ezrin/radixin/moesin family Lipoxygenase PF00305.19 OWF45256.1 - 1.7e-39 135.8 0.0 2.6e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase PLAT PF01477.23 OWF45256.1 - 9.1e-08 32.7 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Ank_2 PF12796.7 OWF45257.1 - 2.3e-207 672.2 0.0 4.9e-10 39.9 0.1 26.7 1 1 35 36 36 36 36 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF45257.1 - 2.9e-120 390.8 0.0 0.00047 20.4 0.0 33.6 25 5 11 36 36 36 30 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF45257.1 - 1.5e-118 385.7 20.8 7.3e-05 23.2 0.0 35.3 26 8 10 38 38 38 23 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF45257.1 - 1.5e-93 295.4 6.4 0.78 10.5 0.0 48.7 56 0 0 56 56 53 15 Ankyrin repeat Ank PF00023.30 OWF45257.1 - 6.3e-57 187.7 0.2 5.6 7.6 0.0 34.4 40 7 0 40 40 39 10 Ankyrin repeat SfsA PF03749.13 OWF45257.1 - 2e-17 63.4 10.9 5.7 6.8 0.0 16.3 22 0 0 22 22 22 3 Sugar fermentation stimulation protein RE domain DUF3447 PF11929.8 OWF45257.1 - 6.8e-16 58.0 22.3 0.0096 15.9 3.0 15.7 8 4 14 22 22 22 4 Domain of unknown function (DUF3447) DUF5388 PF17363.2 OWF45257.1 - 1.5e-14 53.9 1.7 30 4.9 0.0 16.4 20 0 0 20 20 18 0 Family of unknown function (DUF5388) T_Ag_DNA_bind PF02217.16 OWF45257.1 - 3e-14 53.4 0.0 46 4.7 0.0 17.7 23 0 0 23 23 23 0 Origin of replication binding protein YBD PF17725.1 OWF45257.1 - 4.2e-11 43.1 26.8 24 4.7 0.0 20.5 24 0 0 24 24 24 0 YAP binding domain PPR_2 PF13041.6 OWF45257.1 - 4e-10 39.7 0.0 2.6 8.3 0.0 14.0 19 0 0 19 19 19 1 PPR repeat family Cyclin_N PF00134.23 OWF45257.1 - 7.1e-09 35.5 0.0 12 5.6 0.0 12.1 21 0 0 21 21 21 0 Cyclin, N-terminal domain CaM_bdg_C0 PF10562.9 OWF45257.1 - 4.9e-07 29.7 16.4 46 4.2 0.1 16.9 25 0 0 25 25 25 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF4811 PF16069.5 OWF45257.1 - 2.1e-06 27.7 0.0 51 3.7 0.0 8.3 12 0 0 12 12 12 0 Domain of unknown function (DUF4811) DDE_1 PF03184.19 OWF45257.1 - 0.059 13.0 4.2 70 3.0 0.0 7.5 11 0 0 11 11 11 0 DDE superfamily endonuclease BTB PF00651.31 OWF45258.1 - 1e-44 151.3 7.5 2e-20 73.1 0.5 3.4 2 1 1 3 3 3 3 BTB/POZ domain BACK PF07707.15 OWF45258.1 - 0.00011 22.3 0.7 0.0017 18.4 0.1 2.9 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF3342 PF11822.8 OWF45258.1 - 0.0073 16.5 2.3 0.12 12.6 0.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) RIF5_SNase_1 PF18187.1 OWF45258.1 - 0.031 14.0 0.1 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 DUF1736 PF08409.11 OWF45258.1 - 0.065 13.2 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) LisH PF08513.11 OWF45259.1 - 7.7e-05 22.5 1.9 0.00071 19.4 0.4 3.1 3 0 0 3 3 3 1 LisH AT_hook PF02178.19 OWF45260.1 - 1.5 9.0 31.4 1.8 8.7 7.6 3.6 3 0 0 3 3 3 0 AT hook motif FAM176 PF14851.6 OWF45261.1 - 0.0028 17.3 0.0 0.0037 16.9 0.0 1.1 1 0 0 1 1 1 1 FAM176 family TMEM154 PF15102.6 OWF45261.1 - 0.0031 17.4 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 OWF45261.1 - 0.032 15.1 0.0 0.04 14.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 OWF45261.1 - 0.082 11.6 0.0 0.094 11.4 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF5305 PF17231.2 OWF45261.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Amnionless PF14828.6 OWF45261.1 - 0.13 11.0 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF3377 PF11857.8 OWF45261.1 - 0.25 11.3 3.5 0.23 11.4 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) AT_hook PF02178.19 OWF45262.1 - 3.7 7.7 45.9 0.59 10.2 3.3 7.3 6 0 0 6 6 6 0 AT hook motif VWA PF00092.28 OWF45263.1 - 8e-08 32.7 0.0 2.1e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF45263.1 - 0.00053 20.6 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L20 PF00453.18 OWF45263.1 - 1.1 9.4 7.2 0.094 12.8 1.5 2.1 2 0 0 2 2 2 0 Ribosomal protein L20 ILEI PF15711.5 OWF45264.1 - 1.3e-41 141.0 0.2 2.1e-21 76.2 0.1 2.6 2 0 0 2 2 2 2 Interleukin-like EMT inducer GNT-I PF03071.15 OWF45264.1 - 1.7e-13 50.2 0.0 2.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 GNT-I family 7tm_3 PF00003.22 OWF45266.1 - 1.7e-56 191.6 30.4 2.3e-56 191.2 30.4 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OWF45266.1 - 4e-45 154.5 0.1 5.4e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.14 OWF45266.1 - 5.9e-13 48.6 13.2 1.7e-12 47.1 13.2 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR CYYR1 PF10873.8 OWF45267.1 - 0.0014 19.1 11.4 0.002 18.6 11.4 1.2 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 RCR PF12273.8 OWF45267.1 - 0.01 16.5 0.7 0.024 15.3 0.7 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mid2 PF04478.12 OWF45267.1 - 0.31 10.9 0.9 0.44 10.4 0.9 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor rve PF00665.26 OWF45268.1 - 0.0026 17.9 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RasGEF PF00617.19 OWF45269.1 - 7.5e-58 195.6 0.0 1.4e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OWF45269.1 - 8.4e-23 80.6 0.0 1.7e-15 57.1 0.0 2.7 2 0 0 2 2 2 2 RasGEF N-terminal motif PH PF00169.29 OWF45269.1 - 4.5e-06 27.1 0.0 1.7e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 PH domain TFIIA PF03153.13 OWF45269.1 - 0.025 14.6 11.2 0.049 13.6 11.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TGT_C2 PF14810.6 OWF45269.1 - 0.044 13.9 0.3 4.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase DUF533 PF04391.12 OWF45269.1 - 0.32 10.5 2.0 0.57 9.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) zf-C2H2 PF00096.26 OWF45270.1 - 1.1e-41 138.9 85.1 6.3e-05 23.2 0.7 11.9 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF45270.1 - 2.5e-30 103.5 71.4 4.2e-05 23.8 1.9 12.5 12 0 0 12 12 12 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF45270.1 - 4.9e-27 92.3 84.0 0.0074 17.0 0.3 12.2 12 0 0 12 12 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF45270.1 - 5e-10 39.4 44.8 0.12 12.7 0.3 10.9 11 0 0 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF45270.1 - 1e-08 35.0 65.6 0.0029 17.5 1.3 10.4 11 0 0 11 11 11 6 C2H2-type zinc finger zf-met PF12874.7 OWF45270.1 - 0.00016 21.9 58.3 0.036 14.5 0.0 11.1 11 0 0 11 11 11 4 Zinc-finger of C2H2 type ADK_lid PF05191.14 OWF45270.1 - 0.00019 21.3 0.4 0.00019 21.3 0.4 6.2 5 1 0 5 5 5 1 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 OWF45270.1 - 0.048 13.8 32.2 0.12 12.5 0.7 6.6 4 2 4 8 8 8 0 Zinc ribbon domain BolA PF01722.18 OWF45270.1 - 0.14 12.4 4.8 4.3 7.7 0.2 4.5 3 2 1 4 4 4 0 BolA-like protein HypA PF01155.19 OWF45270.1 - 0.88 9.6 24.6 2.4 8.2 0.4 5.2 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OWF45270.1 - 1.1 9.4 31.8 0.21 11.7 4.3 5.4 1 1 1 2 2 1 0 Double zinc ribbon zf_ZIC PF18366.1 OWF45270.1 - 1.3 9.2 24.6 0.29 11.3 0.4 6.0 4 2 3 7 7 7 0 Zic proteins zinc finger domain PyrI_C PF02748.15 OWF45270.1 - 2.5 8.1 12.9 3.8 7.5 0.1 4.8 5 1 0 5 5 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TRAF6_Z2 PF18048.1 OWF45270.1 - 3.1 8.0 8.5 8.3 6.6 0.6 4.0 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 PH PF00169.29 OWF45271.1 - 4.1e-09 36.9 0.0 7.2e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF45271.1 - 0.0037 17.7 0.2 0.0067 16.8 0.0 1.5 2 0 0 2 2 2 1 Pleckstrin homology domain Ribosomal_L22e PF01776.17 OWF45271.1 - 0.095 13.1 0.9 0.12 12.8 0.9 1.1 1 0 0 1 1 1 0 Ribosomal L22e protein family DsbG_N PF18257.1 OWF45272.1 - 0.0033 17.5 0.8 2.3 8.4 0.0 3.4 1 1 3 4 4 4 1 Disulfide isomerase DsbG N-terminal SIS PF01380.22 OWF45272.1 - 0.15 11.9 17.0 4.6 7.1 0.3 5.2 1 1 5 6 6 6 0 SIS domain DUF4464 PF14713.6 OWF45272.1 - 0.32 10.5 8.2 10 5.6 0.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4464) Sm_like PF16243.5 OWF45272.1 - 0.33 11.1 4.1 4 7.7 0.5 3.1 1 1 2 3 3 3 0 Sm_like domain CxxCxxCC PF03692.15 OWF45272.1 - 1 10.1 7.1 2e+02 2.7 6.0 3.7 1 1 0 1 1 1 0 Putative zinc- or iron-chelating domain V-ATPase_H_C PF11698.8 OWF45272.1 - 4.9 7.3 7.8 1.6 8.9 1.5 2.4 1 1 1 2 2 2 0 V-ATPase subunit H IalB PF06776.12 OWF45274.1 - 0.02 14.9 0.2 0.042 13.9 0.1 1.6 1 1 0 1 1 1 0 Invasion associated locus B (IalB) protein Porin_3 PF01459.22 OWF45274.1 - 0.18 11.2 5.5 1.3 8.5 0.7 3.0 1 1 2 3 3 3 0 Eukaryotic porin CopB PF05275.11 OWF45274.1 - 0.39 10.2 2.8 30 4.1 0.1 3.0 1 1 3 4 4 4 0 Copper resistance protein B precursor (CopB) SATase_N PF06426.14 OWF45274.1 - 0.7 10.3 7.3 6 7.3 1.3 2.5 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal L1R_F9L PF02442.17 OWF45274.1 - 0.89 9.4 10.6 0.33 10.8 1.7 2.2 1 1 1 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Yos9_DD PF17880.1 OWF45274.1 - 3.3 7.8 5.6 80 3.4 0.2 3.6 2 1 4 6 6 6 0 Yos9 dimerzation domain DUF2834 PF11196.8 OWF45274.1 - 4 7.8 12.2 46 4.5 0.7 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2834) DUF1062 PF06353.12 OWF45274.1 - 5.8 7.7 6.8 17 6.2 0.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1062) HNH_4 PF13395.6 OWF45275.1 - 0.0095 15.8 17.4 1.9 8.4 0.2 5.3 4 2 1 5 5 5 3 HNH endonuclease RP1-2 PF12042.8 OWF45275.1 - 0.66 9.8 6.5 0.96 9.3 6.5 1.2 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain NT-C2 PF10358.9 OWF45276.1 - 0.0023 17.7 0.0 2 8.1 0.0 3.9 1 1 2 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2972 PF11186.8 OWF45276.1 - 0.016 15.1 1.5 0.67 9.8 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2972) Pox_D2 PF04701.13 OWF45276.1 - 0.032 14.4 3.4 3.2 7.9 0.0 3.4 1 1 1 3 3 3 0 Pox virus D2 protein HNH_4 PF13395.6 OWF45276.1 - 0.032 14.1 10.4 3.1 7.8 0.2 4.6 3 2 0 3 3 3 0 HNH endonuclease MeMO_Hyd_G PF02964.16 OWF45276.1 - 0.18 11.8 0.0 10 6.1 0.0 2.8 2 1 0 3 3 3 0 Methane monooxygenase, hydrolase gamma chain Cyclin_N PF00134.23 OWF45277.1 - 3.5e-48 162.5 2.0 6.4e-48 161.7 0.3 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF45277.1 - 9.9e-25 86.9 2.7 2.6e-24 85.6 2.4 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 OWF45277.1 - 2.7e-13 50.9 2.0 4.3e-13 50.2 2.0 1.3 1 0 0 1 1 1 1 N-terminal region of cyclin_N Ig_Tie2_1 PF10430.9 OWF45277.1 - 0.042 14.2 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 DUF3885 PF13021.6 OWF45278.1 - 2.9 8.1 5.5 10 6.4 0.1 4.2 3 3 2 5 5 5 0 Domain of unknown function (DUF3885) Metallophos PF00149.28 OWF45279.1 - 2.1e-26 93.7 1.8 4.2e-26 92.7 1.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 OWF45279.1 - 6.4e-20 71.4 3.1 1.5e-11 44.6 3.0 3.3 2 1 1 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF45279.1 - 8.7e-17 59.4 1.4 6.2e-07 28.5 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF45279.1 - 2.9e-15 54.8 0.3 5.8e-06 25.8 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 OWF45279.1 - 2.1e-11 42.8 2.6 5.4e-06 25.7 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF45279.1 - 3.9e-08 33.0 4.2 8.8e-06 25.5 1.3 3.5 2 1 1 3 3 3 2 EF-hand domain pair PPP5 PF08321.12 OWF45279.1 - 1.8e-07 31.4 0.5 1.3e-06 28.6 0.0 2.6 3 0 0 3 3 3 1 PPP5 TPR repeat region DUF5475 PF17569.2 OWF45279.1 - 0.00027 21.2 0.6 0.00088 19.5 0.6 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5475) IQ PF00612.27 OWF45279.1 - 0.00042 19.9 2.7 0.00042 19.9 2.7 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif EF-hand_9 PF14658.6 OWF45279.1 - 0.0027 18.0 0.3 3 8.2 0.1 3.2 3 1 0 3 3 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF45279.1 - 0.0029 17.9 1.8 0.71 10.2 0.1 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF45279.1 - 0.02 14.8 4.8 1.2 9.2 0.7 3.3 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 OWF45279.1 - 0.022 14.9 0.3 8 6.6 0.0 2.6 2 0 0 2 2 2 0 p25-alpha NAD_binding_2 PF03446.15 OWF45280.1 - 4.6e-37 127.6 0.2 9.1e-37 126.7 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OWF45280.1 - 8.5e-24 84.1 0.2 1.5e-23 83.3 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.17 OWF45280.1 - 9.5e-20 70.8 0.7 1.9e-19 69.8 0.7 1.5 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.17 OWF45280.1 - 1.3e-07 32.1 0.0 4.7e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OWF45280.1 - 2.4e-05 24.4 0.0 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OWF45280.1 - 5.9e-05 22.8 0.1 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 OWF45280.1 - 0.0069 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OWF45280.1 - 0.0084 16.0 0.2 0.03 14.2 0.3 1.9 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OWF45280.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 OWF45280.1 - 0.097 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AF-4 PF05110.13 OWF45281.1 - 1.2e-88 298.6 133.6 4.5e-77 260.3 52.4 3.6 1 1 2 3 3 3 3 AF-4 proto-oncoprotein potato_inhibit PF00280.18 OWF45282.1 - 5.6e-23 81.4 0.4 6e-23 81.3 0.4 1.0 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.8 OWF45282.1 - 2.3e-08 34.0 0.0 2.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family UPF0016 PF01169.19 OWF45283.1 - 2.9e-44 149.3 22.3 4.1e-23 81.5 5.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 OWF45283.1 - 0.0019 18.0 5.7 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 1 Putative manganese efflux pump DUF2207 PF09972.9 OWF45283.1 - 2.2 7.0 3.4 0.58 8.9 0.1 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) WD40 PF00400.32 OWF45284.1 - 1.3e-48 161.9 32.8 2.4e-07 31.3 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat HHH_3 PF12836.7 OWF45284.1 - 1.2e-15 57.4 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif Nup160 PF11715.8 OWF45284.1 - 2.2e-14 53.0 16.5 0.0037 16.0 0.2 6.9 3 2 4 7 7 7 6 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OWF45284.1 - 2.4e-12 47.0 6.8 0.1 12.9 0.0 7.0 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 OWF45284.1 - 3.6e-11 42.8 1.5 7.2e-11 41.8 1.5 1.6 1 0 0 1 1 1 1 F-box-like HHH PF00633.23 OWF45284.1 - 1.9e-07 30.6 0.1 2.4e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif F-box PF00646.33 OWF45284.1 - 2e-05 24.4 0.2 3.9e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 OWF45284.1 - 0.00045 19.9 5.4 0.005 16.4 3.6 3.1 1 1 1 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 OWF45284.1 - 0.0015 17.5 9.2 4.1 6.3 0.1 5.1 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 OWF45284.1 - 0.0054 16.3 1.9 1 9.0 0.1 3.1 3 1 0 3 3 3 1 Cytolethal distending toxin A/C domain HHH_5 PF14520.6 OWF45284.1 - 0.0077 16.8 0.1 0.097 13.3 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain Nop14 PF04147.12 OWF45284.1 - 0.03 12.6 1.1 0.038 12.2 1.1 1.1 1 0 0 1 1 1 0 Nop14-like family AsnC_trans_reg PF01037.21 OWF45284.1 - 0.037 14.0 0.3 3.3 7.8 0.0 3.8 4 0 0 4 4 4 0 Lrp/AsnC ligand binding domain HHH_6 PF14579.6 OWF45284.1 - 0.038 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif PALB2_WD40 PF16756.5 OWF45284.1 - 0.059 12.3 9.6 1 8.2 0.2 4.8 2 2 4 6 6 6 0 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 OWF45284.1 - 0.083 12.9 0.5 62 3.8 0.0 4.7 5 0 0 5 5 5 0 PQQ enzyme repeat DUF655 PF04919.12 OWF45284.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Hira PF07569.11 OWF45284.1 - 0.11 12.2 3.4 15 5.2 0.0 4.7 1 1 4 5 5 5 0 TUP1-like enhancer of split SDA1 PF05285.12 OWF45284.1 - 0.2 11.0 3.1 0.27 10.6 3.1 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 OWF45284.1 - 1.4 8.6 6.8 2.3 7.9 6.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vps5 PF09325.10 OWF45285.1 - 8.4e-10 38.6 7.8 6.9e-06 25.8 3.2 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.18 OWF45285.1 - 3.6e-08 33.4 8.5 5.8e-08 32.7 8.5 1.3 1 0 0 1 1 1 1 BAR domain PX PF00787.24 OWF45285.1 - 1.2e-07 31.7 0.1 3.9e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 PX domain Terminase_4 PF05119.12 OWF45285.1 - 0.052 14.0 1.8 0.1 13.0 0.3 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit Herpes_UL16 PF03044.14 OWF45285.1 - 0.061 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family Sarcoglycan_1 PF04790.13 OWF45286.1 - 2.2e-42 145.2 0.0 2.8e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein Otopetrin PF03189.13 OWF45287.1 - 4.8e-135 450.8 15.6 8.9e-133 443.3 16.1 2.9 2 1 0 2 2 2 1 Otopetrin DUF4715 PF15835.5 OWF45287.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Med15 PF09606.10 OWF45287.1 - 1.6 7.3 5.2 2.3 6.8 5.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MotB_plug PF13677.6 OWF45287.1 - 1.7 8.3 3.2 4.7 6.9 0.4 2.5 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB Cation_efflux PF01545.21 OWF45288.1 - 2.1e-24 86.4 6.3 2.7e-24 86.0 6.3 1.1 1 0 0 1 1 1 1 Cation efflux family IF3_C PF00707.22 OWF45288.1 - 0.0006 19.7 0.2 0.0016 18.4 0.2 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Amidase_3 PF01520.18 OWF45288.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF4845 PF16137.5 OWF45288.1 - 0.081 13.8 0.1 0.081 13.8 0.1 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4845) Hist_deacetyl PF00850.19 OWF45289.1 - 1.7e-48 165.7 0.4 2.6e-48 165.1 0.4 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Zwilch PF09817.9 OWF45290.1 - 7.7e-53 179.8 5.0 9.6e-53 179.5 5.0 1.1 1 0 0 1 1 1 1 RZZ complex, subunit zwilch DUF2175 PF09943.9 OWF45290.1 - 0.2 12.0 1.5 0.52 10.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) RNase_PH PF01138.21 OWF45291.1 - 5.9e-26 91.5 0.0 1.2e-25 90.6 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OWF45291.1 - 9e-10 38.4 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SCIFF PF13165.6 OWF45291.1 - 0.19 11.7 2.9 2 8.4 0.2 2.4 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF MIEAP PF16026.5 OWF45292.1 - 3.7e-29 102.4 0.0 3.7e-29 102.4 0.0 2.8 2 2 1 3 3 3 1 Mitochondria-eating protein SICA_alpha PF12887.7 OWF45292.1 - 0.038 13.9 0.4 0.038 13.9 0.4 3.3 3 0 0 3 3 3 0 SICA extracellular alpha domain GrpE PF01025.19 OWF45292.1 - 0.12 12.0 7.1 0.28 10.8 6.2 2.0 2 0 0 2 2 2 0 GrpE p450 PF00067.22 OWF45293.1 - 1.5e-106 356.9 0.0 1.7e-106 356.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IF-2 PF11987.8 OWF45294.1 - 0.024 14.7 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Translation-initiation factor 2 DUF4976 PF16347.5 OWF45294.1 - 0.071 13.4 0.2 0.087 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) HSP70 PF00012.20 OWF45296.1 - 2.3e-07 29.4 0.0 1.2e-06 27.1 0.0 2.1 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OWF45296.1 - 0.0069 15.2 0.3 4.2 6.1 0.0 2.8 2 1 1 3 3 3 2 MreB/Mbl protein DDR PF08841.10 OWF45296.1 - 0.081 11.9 0.1 0.24 10.3 0.0 1.8 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain zf-RING_2 PF13639.6 OWF45297.1 - 1e-12 48.1 5.9 2.1e-12 47.2 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF45297.1 - 1.8e-09 37.1 3.5 3.9e-09 36.1 3.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF45297.1 - 4.2e-09 36.1 5.9 7.9e-09 35.2 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF45297.1 - 1.8e-08 34.5 3.7 5.4e-08 33.0 3.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF45297.1 - 2.2e-07 30.7 3.4 2.2e-07 30.7 3.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF45297.1 - 3.5e-07 30.0 5.0 7.9e-07 28.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45297.1 - 6.9e-06 25.8 4.0 1.4e-05 24.8 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OWF45297.1 - 3.3e-05 23.8 3.2 7.1e-05 22.8 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PA PF02225.22 OWF45297.1 - 5.2e-05 23.2 0.1 0.00019 21.4 0.0 2.0 2 0 0 2 2 2 1 PA domain zf-C3HC4_3 PF13920.6 OWF45297.1 - 8e-05 22.4 3.3 0.00016 21.5 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OWF45297.1 - 0.00098 19.1 1.2 0.0024 17.9 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CrgA PF06781.12 OWF45297.1 - 0.0017 18.3 0.1 0.0046 17.0 0.1 1.7 1 0 0 1 1 1 1 Cell division protein CrgA Zn_ribbon_17 PF17120.5 OWF45297.1 - 0.0052 16.4 4.6 0.019 14.6 4.9 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OWF45297.1 - 0.013 15.5 2.3 0.034 14.2 2.3 1.7 1 0 0 1 1 1 0 Zinc-finger PspB PF06667.12 OWF45297.1 - 0.013 15.5 0.4 0.059 13.4 0.3 2.0 2 0 0 2 2 2 0 Phage shock protein B Vps39_2 PF10367.9 OWF45297.1 - 0.027 14.9 0.6 0.09 13.2 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Asp5 PF17000.5 OWF45297.1 - 0.094 12.9 0.5 0.22 11.7 0.5 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 PEN-2 PF10251.9 OWF45297.1 - 0.096 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Zf_RING PF16744.5 OWF45297.1 - 0.21 11.7 2.9 0.58 10.3 2.9 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 OWF45297.1 - 0.25 11.5 5.1 0.72 10.0 5.1 1.8 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 OWF45297.1 - 3 7.8 8.2 0.5 10.3 4.0 2.0 2 0 0 2 2 2 0 PHD-finger RRM_1 PF00076.22 OWF45298.1 - 8.3e-14 51.2 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAUS4 PF14735.6 OWF45298.1 - 0.065 12.9 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 FliD_C PF07195.12 OWF45298.1 - 0.13 11.7 1.0 0.31 10.4 0.2 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Macro PF01661.21 OWF45299.1 - 7.6e-37 126.0 0.0 2.5e-17 63.0 0.0 2.9 3 0 0 3 3 3 2 Macro domain PARP PF00644.20 OWF45299.1 - 3.1e-20 72.6 2.1 7.7e-20 71.3 1.0 2.3 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 OWF45300.1 - 8.8e-35 119.3 0.0 6.8e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 Macro domain PARP PF00644.20 OWF45300.1 - 6.8e-17 61.7 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF3990 PF13151.6 OWF45300.1 - 0.087 12.5 0.9 0.29 10.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3990) ART-PolyVal PF18760.1 OWF45300.1 - 0.14 13.1 0.1 0.37 11.8 0.1 1.6 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins DUF5039 PF16442.5 OWF45300.1 - 0.24 10.9 0.4 0.68 9.4 0.1 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5039) PrmA PF06325.13 OWF45301.1 - 1.9e-06 27.5 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OWF45301.1 - 4.9e-06 27.2 0.0 1.6e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TPR_2 PF07719.17 OWF45301.1 - 6.6e-05 22.7 4.5 0.016 15.3 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF45301.1 - 0.0024 18.5 0.1 6.1 7.9 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat MTS PF05175.14 OWF45301.1 - 0.0025 17.4 0.1 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain TPR_8 PF13181.6 OWF45301.1 - 0.004 17.3 0.8 0.73 10.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_18 PF12847.7 OWF45301.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPR_11 PF13414.6 OWF45301.1 - 0.014 15.1 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 TPR repeat Methyltransf_11 PF08241.12 OWF45301.1 - 0.029 15.0 0.0 0.062 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPR_1 PF00515.28 OWF45301.1 - 0.074 12.9 3.9 0.34 10.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Cons_hypoth95 PF03602.15 OWF45301.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 OWF45301.1 - 0.083 12.2 0.0 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DUF1815 PF08844.10 OWF45301.1 - 0.087 12.8 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) RrnaAD PF00398.20 OWF45301.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 OWF45301.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.31 OWF45303.1 - 3.1e-26 91.3 4.5 6.7e-26 90.2 4.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OWF45303.1 - 4.2e-24 85.3 0.0 7.9e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OWF45303.1 - 1.1e-10 41.8 15.7 2.4e-10 40.6 15.7 1.7 1 0 0 1 1 1 1 DnaJ central domain RR_TM4-6 PF06459.12 OWF45303.1 - 2.3 8.0 13.3 0.3 10.9 8.5 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 WD40_4 PF16300.5 OWF45304.1 - 7e-39 131.5 0.5 1.5e-19 69.6 0.1 2.7 2 0 0 2 2 2 2 Type of WD40 repeat DUF1899 PF08953.11 OWF45304.1 - 6.6e-23 80.4 0.1 2.3e-13 49.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) WD40 PF00400.32 OWF45304.1 - 7.8e-20 70.8 17.0 0.00094 20.0 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF45304.1 - 1.4e-14 54.1 0.0 0.0043 17.3 0.0 6.2 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF45304.1 - 7.6e-05 21.8 0.0 0.011 14.8 0.0 3.6 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF45304.1 - 0.00035 20.5 0.0 0.3 10.9 0.0 3.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A BING4CT PF08149.11 OWF45304.1 - 0.0088 15.8 0.1 3.8 7.4 0.1 2.9 2 0 0 2 2 2 2 BING4CT (NUC141) domain PD40 PF07676.12 OWF45304.1 - 2.2 8.3 4.4 2.1 8.4 0.0 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat HSP70 PF00012.20 OWF45305.1 - 0.0034 15.6 0.0 0.007 14.6 0.0 1.5 1 0 0 1 1 1 1 Hsp70 protein Trypsin PF00089.26 OWF45306.1 - 3.3e-54 184.0 0.5 5.7e-31 108.0 0.0 2.1 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 OWF45306.1 - 1.1e-08 36.1 0.0 1.9e-08 35.4 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF45306.1 - 2.1e-06 28.1 0.0 4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 OWF45306.1 - 0.0017 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Chymotrypsin family Peptidase-S1 DUF4598 PF15370.6 OWF45306.1 - 0.12 12.9 3.2 9.1 6.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) zf-Tim10_DDP PF02953.15 OWF45307.1 - 4.9e-20 70.9 4.1 6.1e-20 70.6 4.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 OWF45307.1 - 0.071 12.8 5.4 0.16 11.7 4.9 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) BEN PF10523.9 OWF45307.1 - 0.15 12.3 0.9 0.37 11.1 0.5 1.7 1 1 1 2 2 2 0 BEN domain cNMP_binding PF00027.29 OWF45308.1 - 4.6e-20 71.5 0.2 6.4e-16 58.2 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ribosomal_L22 PF00237.19 OWF45309.1 - 1.2e-17 64.0 0.1 2.3e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3737 PF12541.8 OWF45309.1 - 0.025 13.8 0.2 0.049 12.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3737) ANAPC4_WD40 PF12894.7 OWF45310.1 - 2.1e-21 76.0 6.1 0.00032 21.0 0.0 7.1 7 1 0 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF45310.1 - 1.6e-17 63.5 35.2 0.00094 20.0 0.0 12.1 13 0 0 13 13 13 5 WD domain, G-beta repeat 4HBT_2 PF13279.6 OWF45311.1 - 3e-19 69.7 0.2 4.1e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OWF45311.1 - 0.15 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily LRR_3 PF07725.12 OWF45314.1 - 2.9e-05 23.7 0.0 82 3.3 0.0 6.8 6 2 2 8 8 8 0 Leucine Rich Repeat PMM PF03332.13 OWF45314.1 - 0.1 12.4 0.5 30 4.3 0.0 3.5 1 1 3 4 4 4 0 Eukaryotic phosphomannomutase HlyD_D4 PF16572.5 OWF45314.1 - 2 8.3 11.3 50 3.9 0.0 6.3 5 2 3 8 8 8 0 Long alpha hairpin domain of cation efflux system protein, CusB LRR_3 PF07725.12 OWF45315.1 - 1.2e-05 25.0 0.3 28 4.8 0.0 6.6 5 4 4 9 9 9 1 Leucine Rich Repeat Ldr_toxin PF13940.6 OWF45315.1 - 0.033 14.3 3.3 3.4 7.8 0.3 3.7 1 1 2 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system PMM PF03332.13 OWF45315.1 - 0.32 10.7 0.3 17 5.1 0.0 2.8 1 1 0 2 2 2 0 Eukaryotic phosphomannomutase HlyD_D4 PF16572.5 OWF45315.1 - 0.64 9.9 9.0 33 4.5 0.0 5.5 4 2 2 6 6 6 0 Long alpha hairpin domain of cation efflux system protein, CusB Polysacc_deac_1 PF01522.21 OWF45317.1 - 0.0001 22.2 0.1 0.0004 20.3 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide deacetylase IQ PF00612.27 OWF45319.1 - 9.9e-10 37.4 6.1 8.6e-05 22.0 0.1 3.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif Pan3_PK PF18101.1 OWF45320.1 - 2e-64 215.7 0.1 2.9e-64 215.2 0.1 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain zf-CCCH PF00642.24 OWF45320.1 - 4.1e-07 29.8 2.5 7.8e-07 28.9 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF45320.1 - 1.6e-06 27.9 4.1 3.2e-06 27.0 4.1 1.5 1 0 0 1 1 1 1 Zinc finger domain Pkinase PF00069.25 OWF45320.1 - 3.8e-05 23.2 0.0 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain zf-CCCH_4 PF18044.1 OWF45320.1 - 6.5e-05 22.6 2.1 0.00013 21.7 2.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OWF45320.1 - 0.0015 18.9 3.4 0.0045 17.4 3.4 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OWF45320.1 - 0.013 16.2 0.4 0.026 15.2 0.4 1.4 1 0 0 1 1 1 0 Torus domain Neur_chan_LBD PF02931.23 OWF45321.1 - 3.1e-48 164.1 1.2 4e-48 163.7 1.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45321.1 - 2.3e-30 106.4 5.9 7.6e-26 91.6 3.4 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF45322.1 - 2.2e-46 158.1 2.9 3e-46 157.6 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45322.1 - 1.2e-31 110.6 8.4 3.1e-28 99.4 3.6 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region SKICH PF17751.1 OWF45323.1 - 2.3e-24 85.9 0.0 6.6e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 SKICH domain SlyX PF04102.12 OWF45323.1 - 0.0019 18.8 0.7 0.0019 18.8 0.7 3.2 3 0 0 3 3 3 1 SlyX ATG16 PF08614.11 OWF45323.1 - 0.0044 17.3 0.8 0.0044 17.3 0.8 3.3 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 OWF45323.1 - 0.019 14.8 0.2 0.071 13.0 0.2 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Spc29 PF17082.5 OWF45323.1 - 0.024 14.5 7.9 0.03 14.2 1.2 2.4 2 0 0 2 2 2 0 Spindle Pole Component 29 GATA PF00320.27 OWF45323.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 GATA zinc finger Fib_alpha PF08702.10 OWF45323.1 - 0.25 11.5 12.8 2.4 8.4 2.5 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 OWF45323.1 - 2.2 7.8 9.6 0.18 11.3 2.6 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1515 PF07439.11 OWF45323.1 - 8.1 6.5 13.1 0.83 9.7 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Peptidase_M2 PF01401.18 OWF45324.1 - 0 3954.7 77.4 1.4e-241 803.1 11.4 9.3 6 3 3 9 9 9 9 Angiotensin-converting enzyme DUF2119 PF09892.9 OWF45324.1 - 0.23 10.8 4.1 9.1 5.6 0.2 4.1 3 1 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2119) DUF1870 PF08965.10 OWF45324.1 - 0.61 10.1 6.4 17 5.5 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1870) DUF1054 PF06335.12 OWF45324.1 - 1 9.3 5.5 83 3.0 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1054) DUF3176 PF11374.8 OWF45324.1 - 1.8 8.8 11.5 3 8.1 0.1 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3176) Peptidase_M2 PF01401.18 OWF45325.1 - 1.6e-243 809.5 1.1 1.8e-243 809.3 1.1 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF4949 PF16307.5 OWF45326.1 - 0.0006 19.9 0.3 0.11 12.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4949) GP3 PF03076.14 OWF45326.1 - 0.068 13.2 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Equine arteritis virus GP3 YlbD_coat PF14071.6 OWF45326.1 - 0.16 12.2 1.3 6.6 7.0 0.2 2.4 1 1 1 2 2 2 0 Putative coat protein Helicase_C PF00271.31 OWF45327.1 - 7.1e-10 39.2 0.1 2.2e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OWF45327.1 - 0.0024 18.6 0.1 0.0051 17.5 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding PEHE PF15275.6 OWF45329.1 - 2.9e-06 27.9 17.5 2.9e-06 27.9 17.5 6.3 7 3 1 8 8 8 1 PEHE domain Ninjurin PF04923.12 OWF45330.1 - 2.5e-18 65.9 6.5 3.4e-18 65.5 6.5 1.1 1 0 0 1 1 1 1 Ninjurin SUR7 PF06687.12 OWF45330.1 - 0.027 14.1 0.6 0.029 14.0 0.6 1.1 1 0 0 1 1 1 0 SUR7/PalI family DASH_Duo1 PF08651.10 OWF45331.1 - 1.4e-12 47.2 36.1 0.0045 16.7 4.8 5.1 1 1 5 6 6 6 6 DASH complex subunit Duo1 DegQ PF08181.11 OWF45331.1 - 1.9e-12 47.1 70.0 0.039 14.1 0.3 12.4 1 1 15 16 16 16 1 DegQ (SacQ) family DUF3552 PF12072.8 OWF45331.1 - 9e-12 44.8 48.3 0.0019 17.7 9.1 3.9 1 1 3 4 4 4 4 Domain of unknown function (DUF3552) Tropomyosin PF00261.20 OWF45331.1 - 1.8e-10 40.6 37.9 0.00017 21.0 10.5 3.0 1 1 2 3 3 3 3 Tropomyosin DUF948 PF06103.11 OWF45331.1 - 2.9e-10 40.2 38.7 1.8e+04 -10.3 38.7 4.4 1 1 0 1 1 0 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 OWF45331.1 - 3.8e-10 39.9 44.5 0.00053 20.0 10.8 3.8 1 1 3 4 4 4 4 Laminin Domain II DUF745 PF05335.13 OWF45331.1 - 4.8e-10 39.5 40.4 6.7e-06 25.9 19.7 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF745) YkyA PF10368.9 OWF45331.1 - 2.6e-09 37.0 39.0 0.00087 19.0 17.3 3.1 1 1 2 3 3 3 3 Putative cell-wall binding lipoprotein Exonuc_VII_S PF02609.16 OWF45331.1 - 1.8e-08 34.3 15.0 0.039 14.0 0.4 4.5 1 1 3 4 4 4 4 Exonuclease VII small subunit TMP_2 PF06791.13 OWF45331.1 - 3.9e-08 33.2 20.8 0.023 14.4 0.8 3.9 1 1 3 4 4 4 4 Prophage tail length tape measure protein MCPsignal PF00015.21 OWF45331.1 - 8.4e-08 32.2 21.1 0.0039 17.0 3.4 3.1 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain TPR_MLP1_2 PF07926.12 OWF45331.1 - 1.8e-07 31.2 52.6 0.022 14.8 16.5 3.4 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 OWF45331.1 - 1.1e-06 28.4 62.9 0.0021 17.7 42.9 2.4 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain APG17 PF04108.12 OWF45331.1 - 1.5e-06 27.6 40.9 0.0022 17.2 17.6 2.3 1 1 1 2 2 2 2 Autophagy protein Apg17 DUF3584 PF12128.8 OWF45331.1 - 1.6e-06 26.0 45.9 0.0032 15.1 27.6 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) BORCS7 PF16088.5 OWF45331.1 - 1.8e-06 28.1 42.7 0.17 12.2 6.7 4.4 1 1 3 4 4 4 2 BLOC-1-related complex sub-unit 7 EzrA PF06160.12 OWF45331.1 - 2.1e-06 26.2 40.0 0.00054 18.3 21.9 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA WXG100 PF06013.12 OWF45331.1 - 4.1e-06 26.9 37.7 0.83 9.9 2.8 5.6 1 1 5 6 6 6 2 Proteins of 100 residues with WXG HrpB7 PF09486.10 OWF45331.1 - 8.2e-06 26.3 19.7 0.043 14.2 5.3 3.5 1 1 2 3 3 3 3 Bacterial type III secretion protein (HrpB7) RPW8 PF05659.11 OWF45331.1 - 9.1e-06 25.4 21.0 0.029 14.1 1.1 4.1 1 1 2 3 3 3 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tropomyosin_1 PF12718.7 OWF45331.1 - 1e-05 25.7 48.6 0.0015 18.7 30.3 2.4 1 1 1 2 2 2 2 Tropomyosin like HiaBD2 PF15403.6 OWF45331.1 - 1.2e-05 25.6 58.6 3 8.3 0.8 8.9 1 1 6 7 7 7 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF4200 PF13863.6 OWF45331.1 - 1.4e-05 25.5 34.8 0.036 14.5 14.0 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF4200) Laminin_I PF06008.14 OWF45331.1 - 1.5e-05 24.9 54.6 0.0024 17.6 24.3 2.4 1 1 1 2 2 2 2 Laminin Domain I Plasmid_RAQPRD PF09686.10 OWF45331.1 - 2.9e-05 24.2 30.6 1.8e+04 -17.6 30.6 6.8 1 1 0 1 1 0 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Spc7 PF08317.11 OWF45331.1 - 3.1e-05 23.0 45.7 0.0031 16.5 28.8 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Fusion_gly PF00523.18 OWF45331.1 - 3.1e-05 22.4 48.6 0.29 9.3 4.4 5.6 1 1 6 7 7 7 5 Fusion glycoprotein F0 YscO-like PF16789.5 OWF45331.1 - 3.5e-05 23.9 23.1 0.12 12.4 18.6 3.5 1 1 1 2 2 2 2 YscO-like protein Cep57_CLD_2 PF14197.6 OWF45331.1 - 6.1e-05 23.0 52.1 1.2 9.3 3.4 6.0 1 1 5 6 6 6 2 Centrosome localisation domain of PPC89 DASH_Dad1 PF08649.10 OWF45331.1 - 7.8e-05 22.8 22.4 14 6.0 1.0 6.9 1 1 6 7 7 7 0 DASH complex subunit Dad1 FliJ PF02050.16 OWF45331.1 - 0.00011 22.4 33.3 0.14 12.4 9.3 3.1 1 1 2 3 3 3 3 Flagellar FliJ protein KfrA_N PF11740.8 OWF45331.1 - 0.00011 22.8 22.1 2.2 9.0 2.5 4.7 1 1 5 6 6 6 0 Plasmid replication region DNA-binding N-term IFT57 PF10498.9 OWF45331.1 - 0.00018 20.6 40.0 0.019 14.0 18.6 2.3 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 SNARE PF05739.19 OWF45331.1 - 0.00019 21.4 44.2 1.1 9.3 1.3 7.9 1 1 8 9 9 9 2 SNARE domain DUF2524 PF10732.9 OWF45331.1 - 0.00019 21.7 29.3 0.94 9.8 1.9 4.0 1 1 3 4 4 4 3 Protein of unknown function (DUF2524) Exonuc_VII_L PF02601.15 OWF45331.1 - 0.00022 20.9 43.5 0.028 14.0 23.2 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit FH2 PF02181.23 OWF45331.1 - 0.00025 20.3 32.1 0.053 12.6 7.4 3.0 1 1 2 3 3 3 3 Formin Homology 2 Domain UPF0184 PF03670.13 OWF45331.1 - 0.00026 21.3 41.0 11 6.5 2.2 7.7 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0184) Uds1 PF15456.6 OWF45331.1 - 0.00049 20.3 40.7 1.8e+04 -9.6 40.7 3.3 1 1 0 1 1 0 0 Up-regulated During Septation DUF1664 PF07889.12 OWF45331.1 - 0.00053 20.0 36.3 1.8e+04 -10.2 36.3 3.5 1 1 0 1 1 0 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 OWF45331.1 - 0.00066 19.6 61.9 1.8e+04 -37.4 61.9 5.2 1 1 0 1 1 0 0 TATA element modulatory factor 1 DNA binding HBM PF16591.5 OWF45331.1 - 0.00072 19.1 40.6 1.4 8.3 8.7 4.0 1 1 1 2 2 2 1 Helical bimodular sensor domain Sec8_exocyst PF04048.14 OWF45331.1 - 0.00085 19.2 48.4 1.6 8.6 3.5 5.1 1 1 4 5 5 5 0 Sec8 exocyst complex component specific domain KASH_CCD PF14662.6 OWF45331.1 - 0.0009 19.1 51.9 2.7e+02 1.2 51.9 2.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 OWF45331.1 - 0.0011 19.4 44.9 4 7.9 5.4 5.5 1 1 5 6 6 6 0 Cell division protein ZapB SesA PF17107.5 OWF45331.1 - 0.0012 19.1 29.1 1.8e+04 -5.3 29.1 3.4 1 1 0 1 1 0 0 N-terminal domain on NACHT_NTPase and P-loop NTPases OEP PF02321.18 OWF45331.1 - 0.0014 18.5 38.3 0.19 11.5 10.6 3.4 1 1 2 3 3 3 2 Outer membrane efflux protein CheZ PF04344.13 OWF45331.1 - 0.0014 18.5 32.5 0.25 11.2 7.1 2.9 1 1 1 2 2 2 1 Chemotaxis phosphatase, CheZ Transcrip_act PF04949.13 OWF45331.1 - 0.0031 17.4 13.4 4.4e+02 0.7 13.4 4.2 1 1 0 1 1 1 0 Transcriptional activator V-SNARE PF05008.15 OWF45331.1 - 0.0038 17.6 42.7 1.7 9.1 3.9 5.1 1 1 3 4 4 4 0 Vesicle transport v-SNARE protein N-terminus RmuC PF02646.16 OWF45331.1 - 0.0039 16.4 40.2 0.91 8.6 3.4 4.3 1 1 4 5 5 5 2 RmuC family WEMBL PF05701.11 OWF45331.1 - 0.0052 15.5 31.7 0.0081 14.9 31.7 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DLP_helical PF18709.1 OWF45331.1 - 0.0075 15.5 32.8 0.34 10.0 3.5 4.0 1 1 3 4 4 4 1 Dynamin-like helical domain FIVAR PF07554.13 OWF45331.1 - 0.0075 17.0 71.4 1.2 9.9 20.6 4.7 1 1 4 5 5 5 1 FIVAR domain DHR10 PF18595.1 OWF45331.1 - 0.0084 16.2 43.0 1.8e+04 -10.2 43.0 3.1 1 1 0 1 1 0 0 Designed helical repeat protein 10 domain HMMR_N PF15905.5 OWF45331.1 - 0.0087 15.6 42.0 0.39 10.1 20.6 2.1 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal YscO PF07321.12 OWF45331.1 - 0.0089 16.0 25.1 3 7.8 2.0 4.2 1 1 3 4 4 4 0 Type III secretion protein YscO YojJ PF10372.9 OWF45331.1 - 0.012 15.7 25.8 22 5.2 0.6 6.7 1 1 2 3 3 2 0 Bacterial membrane-spanning protein N-terminus bZIP_1 PF00170.21 OWF45331.1 - 0.014 15.5 44.3 4.9 7.3 2.7 6.1 1 1 6 7 7 7 0 bZIP transcription factor TMPIT PF07851.13 OWF45331.1 - 0.02 14.1 41.4 0.58 9.3 15.5 2.9 1 1 1 2 2 2 0 TMPIT-like protein TelA PF05816.11 OWF45331.1 - 0.027 13.6 39.2 0.46 9.5 17.3 2.2 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) APG6_N PF17675.1 OWF45331.1 - 0.028 14.9 44.0 1.8e+04 -5.8 44.0 2.5 1 1 0 1 1 0 0 Apg6 coiled-coil region AAA_13 PF13166.6 OWF45331.1 - 0.03 13.0 42.3 0.029 13.0 32.0 1.9 1 1 1 2 2 2 0 AAA domain T3SSipB PF16535.5 OWF45331.1 - 0.034 14.6 52.0 60 4.1 27.6 4.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB HemX PF04375.14 OWF45331.1 - 0.035 13.4 54.5 1.1 8.5 14.1 3.0 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Syntaxin-6_N PF09177.11 OWF45331.1 - 0.037 14.6 38.0 1.8e+04 -11.7 38.0 3.5 1 1 0 1 1 0 0 Syntaxin 6, N-terminal Caskin-tail PF16632.5 OWF45331.1 - 0.038 14.4 33.0 25 5.3 1.9 8.0 1 1 2 3 3 2 0 C-terminal region of Caskin Myosin_tail_1 PF01576.19 OWF45331.1 - 0.041 11.7 35.9 0.087 10.6 23.8 1.8 1 1 0 1 1 1 0 Myosin tail Imm6 PF14434.6 OWF45331.1 - 0.043 13.8 21.6 7.8 6.5 0.8 4.9 1 1 2 3 3 3 0 Immunity protein Imm6 Jnk-SapK_ap_N PF09744.9 OWF45331.1 - 0.045 14.0 41.9 1.8e+04 -9.6 41.9 2.8 1 1 0 1 1 0 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 OWF45331.1 - 0.052 12.8 47.1 1.2 8.4 21.2 2.7 1 1 1 2 2 1 0 Protein of unknown function (DUF3450) DegS PF05384.11 OWF45331.1 - 0.07 12.6 24.2 4.3 6.8 15.3 3.1 1 1 1 2 2 2 0 Sensor protein DegS Uso1_p115_C PF04871.13 OWF45331.1 - 0.075 13.4 52.9 1.8e+04 -24.6 52.9 3.7 1 1 0 1 1 0 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2229 PF09989.9 OWF45331.1 - 0.082 12.5 14.8 0.022 14.4 1.9 2.7 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) BLOC1_2 PF10046.9 OWF45331.1 - 0.12 12.7 43.6 1.8e+04 -19.0 43.6 3.7 1 1 0 1 1 0 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0449 PF15136.6 OWF45331.1 - 0.13 12.7 40.9 1.8e+04 -21.9 40.9 4.9 1 1 0 1 1 0 0 Uncharacterised protein family UPF0449 DUF16 PF01519.16 OWF45331.1 - 0.15 12.5 42.0 28 5.3 20.1 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 OWF45331.1 - 0.2 12.3 46.4 2.5e+03 -0.9 23.9 4.1 1 1 1 2 2 0 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LXG PF04740.12 OWF45331.1 - 0.21 11.3 47.2 0.97 9.1 14.6 3.3 1 1 2 3 3 3 0 LXG domain of WXG superfamily BAR PF03114.18 OWF45331.1 - 0.24 11.0 39.1 0.54 9.9 15.8 2.2 1 1 1 2 2 2 0 BAR domain DivIC PF04977.15 OWF45331.1 - 0.24 11.2 52.2 8.4 6.3 4.4 6.1 1 1 5 6 6 5 0 Septum formation initiator Sec20 PF03908.13 OWF45331.1 - 0.24 11.3 39.9 44 4.1 11.3 4.2 1 1 3 4 4 3 0 Sec20 Snf7 PF03357.21 OWF45331.1 - 0.28 10.7 46.0 30 4.2 7.7 3.4 1 1 1 2 2 2 0 Snf7 KxDL PF10241.9 OWF45331.1 - 0.35 11.2 45.5 9.9 6.5 12.2 4.1 1 1 1 2 2 1 0 Uncharacterized conserved protein PTS_IIA PF02255.16 OWF45331.1 - 0.64 10.1 24.2 21 5.2 1.1 6.4 1 1 3 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit ADIP PF11559.8 OWF45331.1 - 0.73 9.9 58.8 4.2 7.4 16.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 OWF45331.1 - 0.74 9.3 35.8 20 4.7 17.1 2.6 1 1 1 2 2 2 0 Intermediate filament protein CALCOCO1 PF07888.11 OWF45331.1 - 0.75 8.6 34.6 0.99 8.2 34.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF812 PF05667.11 OWF45331.1 - 0.75 8.6 42.2 38 3.0 42.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) I_LWEQ PF01608.17 OWF45331.1 - 0.81 9.9 38.8 14 5.9 17.4 2.9 1 1 2 3 3 3 0 I/LWEQ domain V-SNARE_C PF12352.8 OWF45331.1 - 0.83 10.0 35.6 2.5 8.4 6.4 4.5 1 1 3 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus ISG65-75 PF11727.8 OWF45331.1 - 0.84 8.8 33.4 1.4 8.0 12.1 2.6 1 1 1 2 2 2 0 Invariant surface glycoprotein Prefoldin PF02996.17 OWF45331.1 - 0.86 9.5 42.4 1.8e+04 -4.8 18.0 5.2 1 1 1 2 2 0 0 Prefoldin subunit DASH_Dam1 PF08653.10 OWF45331.1 - 0.88 9.4 39.8 13 5.7 1.5 7.5 1 1 9 10 10 10 0 DASH complex subunit Dam1 Rogdi_lz PF10259.9 OWF45331.1 - 1 8.8 35.4 2 7.8 8.2 3.2 1 1 1 2 2 1 0 Rogdi leucine zipper containing protein GAS PF13851.6 OWF45331.1 - 1.1 8.6 45.9 5 6.4 21.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_HK97_TLTM PF06120.11 OWF45331.1 - 1.1 8.3 41.4 3.5e+02 0.2 41.4 3.0 1 1 0 1 1 1 0 Tail length tape measure protein Dermcidin PF15291.6 OWF45331.1 - 1.1 9.8 17.4 1.8e+04 -8.3 17.4 5.0 1 1 0 1 1 0 0 Dermcidin, antibiotic peptide DUF4686 PF15742.5 OWF45331.1 - 1.2 8.2 50.8 7.3e+02 -1.0 50.8 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Borrelia_P83 PF05262.11 OWF45331.1 - 1.3 7.5 47.2 19 3.6 13.9 3.2 1 1 1 2 2 2 0 Borrelia P83/100 protein Snapin_Pallidin PF14712.6 OWF45331.1 - 1.3 9.4 45.3 4.3 7.8 11.5 3.6 1 1 1 2 2 1 0 Snapin/Pallidin Golgin_A5 PF09787.9 OWF45331.1 - 1.6 8.1 39.2 6.3 6.2 20.4 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 ATG16 PF08614.11 OWF45331.1 - 1.8 8.8 52.6 1.9 8.6 39.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LOH1CR12 PF10158.9 OWF45331.1 - 2.1 8.4 17.6 36 4.4 4.1 3.6 1 1 1 2 2 2 0 Tumour suppressor protein Vps54_N PF10475.9 OWF45331.1 - 2.2 7.5 26.0 6 6.0 6.4 3.3 1 1 2 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex STAT_alpha PF01017.20 OWF45331.1 - 2.9 7.8 42.0 0.94 9.4 12.4 3.3 1 1 1 2 2 1 0 STAT protein, all-alpha domain Mce4_CUP1 PF11887.8 OWF45331.1 - 2.9 7.3 33.2 27 4.1 13.1 3.5 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative TACC_C PF05010.14 OWF45331.1 - 3.5 7.3 36.8 6.8e+02 -0.1 36.8 2.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SpecificRecomb PF10136.9 OWF45331.1 - 3.8 5.7 16.4 6.9 4.8 5.9 2.1 1 1 1 2 2 2 0 Site-specific recombinase Fez1 PF06818.15 OWF45331.1 - 4.7 7.6 39.6 14 6.0 21.3 2.1 1 1 1 2 2 2 0 Fez1 JIP_LZII PF16471.5 OWF45331.1 - 5.9 7.1 33.7 23 5.3 0.3 4.8 1 1 4 5 5 5 0 JNK-interacting protein leucine zipper II LMBR1 PF04791.16 OWF45331.1 - 6.2 5.6 41.1 6.4 5.6 20.2 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF4695 PF15766.5 OWF45331.1 - 6.6 7.0 31.2 25 5.1 2.6 5.3 1 1 1 2 2 1 0 Domain of unknown function (DUF4695) SKA1 PF07160.12 OWF45331.1 - 7.6 6.3 36.6 1.1e+04 -4.1 36.6 4.0 1 1 0 1 1 0 0 Spindle and kinetochore-associated protein 1 Lebercilin PF15619.6 OWF45331.1 - 7.6 6.1 50.1 8.3 6.0 29.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.13 OWF45331.1 - 8.8 6.4 48.7 1.8e+04 -18.2 48.7 3.3 1 1 0 1 1 0 0 Modifier of rudimentary (Mod(r)) protein D123 PF07065.14 OWF45332.1 - 2.5e-22 79.4 0.7 8.8e-22 77.6 0.2 1.9 2 0 0 2 2 2 1 D123 R2K_2 PF18299.1 OWF45332.1 - 0.0045 16.9 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 2 Acyl-CoA_dh_1 PF00441.24 OWF45333.1 - 1.3e-19 70.9 0.0 1.6e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 OWF45333.1 - 0.06 13.6 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain VASP_tetra PF08776.11 OWF45334.1 - 1e-05 25.0 16.8 0.027 14.1 0.3 4.6 1 1 4 5 5 5 5 VASP tetramerisation domain DrrA_P4M PF14860.6 OWF45334.1 - 0.0084 15.9 10.4 0.32 10.9 2.6 2.8 1 1 1 2 2 2 2 DrrA phosphatidylinositol 4-phosphate binding domain MinE PF03776.14 OWF45334.1 - 0.027 14.5 11.2 8 6.6 0.1 4.7 1 1 0 2 2 2 0 Septum formation topological specificity factor MinE Orthopox_F6 PF06601.12 OWF45334.1 - 0.29 11.3 6.6 17 5.6 0.7 4.0 1 1 2 3 3 3 0 Orthopoxvirus F6 protein RRM_8 PF11835.8 OWF45334.1 - 3.7 7.8 7.6 3.8 7.8 1.8 2.3 1 1 1 2 2 2 0 RRM-like domain LolA_like PF17131.4 OWF45334.1 - 9.8 5.9 9.4 13 5.5 9.4 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein Acyl-CoA_dh_1 PF00441.24 OWF45335.1 - 1.4e-41 142.2 0.4 2.1e-41 141.6 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OWF45335.1 - 1.7e-32 112.4 0.1 4.7e-32 111.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OWF45335.1 - 4.7e-28 97.2 0.0 1e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OWF45335.1 - 5.5e-08 33.2 0.0 9.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 OWF45335.1 - 0.012 16.2 0.0 0.035 14.7 0.0 1.9 2 1 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Methyltransf_33 PF10017.9 OWF45336.1 - 3.2e-55 187.4 0.0 4e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_12 PF08242.12 OWF45336.1 - 0.082 13.7 0.0 0.24 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OWF45336.1 - 0.15 12.8 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 OWF45337.1 - 1.2e-54 185.6 0.0 1.4e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_12 PF08242.12 OWF45337.1 - 0.11 13.3 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WSC PF01822.19 OWF45338.1 - 2.3e-07 30.9 8.0 1.1e-06 28.7 8.0 2.3 1 0 0 1 1 1 1 WSC domain Lectin_C PF00059.21 OWF45338.1 - 0.00035 21.3 6.3 0.85 10.4 0.2 4.2 3 1 0 3 3 3 2 Lectin C-type domain Lectin_C PF00059.21 OWF45339.1 - 2e-17 63.9 0.3 2.6e-17 63.5 0.3 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF45339.1 - 0.0012 18.5 0.8 0.0029 17.3 0.8 1.7 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lysyl_oxidase PF01186.17 OWF45340.1 - 4.6e-92 307.3 1.1 4.6e-92 307.3 1.1 1.4 2 0 0 2 2 2 1 Lysyl oxidase SRCR PF00530.18 OWF45340.1 - 1.3e-36 125.1 15.7 1.2e-21 77.1 0.6 3.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF45340.1 - 7.2e-07 29.7 1.8 0.012 16.1 0.1 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF45340.1 - 0.0077 16.7 0.1 1.2 9.7 0.0 2.7 2 0 0 2 2 2 1 Hepsin, SRCR domain Y_Y_Y PF07495.13 OWF45340.1 - 0.089 12.8 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Y_Y_Y domain DUF3439 PF11921.8 OWF45340.1 - 0.84 9.6 8.7 1.8 8.6 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) 7tm_1 PF00001.21 OWF45341.1 - 1.5e-50 172.0 27.4 1.8e-50 171.7 27.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF45341.1 - 4e-08 33.0 30.7 5.5e-08 32.5 30.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Fumble PF03630.14 OWF45342.1 - 3.5e-118 394.6 0.1 4.3e-118 394.3 0.1 1.1 1 0 0 1 1 1 1 Fumble Rad21_Rec8_N PF04825.13 OWF45343.1 - 3e-08 33.8 0.0 6.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Synaphin PF05835.12 OWF45345.1 - 1.5e-41 142.0 17.0 1.9e-41 141.7 17.0 1.0 1 0 0 1 1 1 1 Synaphin protein Ferlin_C PF16165.5 OWF45345.1 - 0.15 12.0 7.5 0.2 11.6 7.5 1.1 1 0 0 1 1 1 0 Ferlin C-terminus DUF5401 PF17380.2 OWF45345.1 - 0.24 9.4 13.5 0.29 9.2 13.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Spore_III_AF PF09581.10 OWF45345.1 - 0.53 10.3 7.3 0.17 11.9 3.7 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) GEN1_C PF18380.1 OWF45345.1 - 2.1 9.3 9.2 4.8 8.1 2.8 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Na_Ca_ex_C PF16494.5 OWF45345.1 - 2.5 8.6 9.5 1.9 8.9 8.4 1.4 1 1 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain tRNA_bind_2 PF13725.6 OWF45345.1 - 2.7 7.7 7.0 0.67 9.6 4.2 1.4 2 0 0 2 2 2 0 Possible tRNA binding domain DUF3652 PF12372.8 OWF45346.1 - 8.2e-19 67.2 0.2 8.2e-19 67.2 0.2 2.1 2 0 0 2 2 2 1 Huntingtin protein region HEAT PF02985.22 OWF45346.1 - 8.9e-09 34.9 2.8 0.89 10.0 0.0 5.8 4 0 0 4 4 4 4 HEAT repeat HEAT_2 PF13646.6 OWF45346.1 - 0.00021 21.6 0.8 11 6.5 0.0 5.4 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 OWF45346.1 - 0.0024 18.3 1.6 12 6.6 0.0 4.9 4 0 0 4 4 4 1 HEAT-like repeat V-ATPase_H_C PF11698.8 OWF45346.1 - 0.037 14.1 0.6 1.1 9.4 0.1 3.3 3 0 0 3 3 3 0 V-ATPase subunit H Arm PF00514.23 OWF45346.1 - 0.52 10.4 1.9 2.2 8.5 0.1 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat NIF PF03031.18 OWF45347.1 - 9.3e-30 103.5 0.4 1.5e-29 102.8 0.4 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 OWF45347.1 - 1.3e-08 34.4 0.0 3.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Snf7 PF03357.21 OWF45348.1 - 7.2e-37 126.6 18.6 7.2e-37 126.6 18.6 1.7 2 0 0 2 2 2 1 Snf7 PYC_OADA PF02436.18 OWF45348.1 - 0.0016 18.3 3.4 0.32 10.7 0.5 2.3 2 1 0 2 2 2 2 Conserved carboxylase domain PDEase_I PF00233.19 OWF45348.1 - 0.0032 17.2 3.9 0.0044 16.8 3.9 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_S21 PF01165.20 OWF45348.1 - 0.025 14.3 3.5 0.13 12.0 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S21 Ribophorin_II PF05817.14 OWF45348.1 - 0.058 11.9 2.4 0.063 11.8 2.4 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II VanY PF02557.17 OWF45348.1 - 0.12 12.2 1.8 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase MqsR_toxin PF15723.5 OWF45348.1 - 0.12 12.7 1.9 0.24 11.8 0.4 2.3 1 1 1 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA Sec20 PF03908.13 OWF45348.1 - 1.5 8.8 6.1 0.94 9.4 1.1 2.4 1 1 1 2 2 2 0 Sec20 DUF1824 PF08854.10 OWF45348.1 - 1.6 8.6 4.4 1.3 9.0 0.4 2.3 2 1 0 3 3 3 0 Domain of unknown function (DUF1824) MIEAP PF16026.5 OWF45348.1 - 2.1 8.5 6.8 1.6 8.9 0.2 2.7 1 1 2 3 3 3 0 Mitochondria-eating protein Ank_4 PF13637.6 OWF45349.1 - 8.1e-40 134.7 4.2 1e-13 51.5 0.1 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF45349.1 - 3.2e-38 130.2 6.1 1.5e-10 41.5 0.3 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF45349.1 - 5e-30 103.2 3.6 8e-07 29.2 0.2 7.2 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF45349.1 - 1.2e-28 98.2 5.9 4.5e-06 26.9 0.2 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OWF45349.1 - 9.5e-28 93.2 3.3 8.6e-05 22.7 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat SOCS_box PF07525.16 OWF45349.1 - 6.5e-13 48.8 2.5 1.3e-12 47.8 2.5 1.6 1 0 0 1 1 1 1 SOCS box ERCC4 PF02732.15 OWF45350.1 - 3e-10 40.5 0.0 6.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain CUE PF02845.16 OWF45350.1 - 0.00027 20.5 0.1 0.00073 19.2 0.1 1.8 1 0 0 1 1 1 1 CUE domain zinc-ribbon_6 PF10005.9 OWF45351.1 - 0.00012 22.7 21.7 48 4.7 0.1 8.7 1 1 12 14 14 14 0 zinc-ribbon domain DnaA_N PF11638.8 OWF45351.1 - 0.87 9.4 3.7 98 2.8 0.1 4.7 2 2 2 4 4 4 0 DnaA N-terminal domain UPF0524 PF15823.5 OWF45351.1 - 0.9 8.9 14.2 2.3 7.5 0.7 4.9 2 2 4 6 6 6 0 UPF0524 of C3orf70 A-2_8-polyST PF07388.11 OWF45351.1 - 2.9 6.4 19.0 5.6 5.4 0.8 4.6 1 1 4 5 5 5 0 Alpha-2,8-polysialyltransferase (POLYST) JmjC PF02373.22 OWF45352.1 - 1.1e-13 51.6 0.7 1e-12 48.5 0.0 3.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase FYVE PF01363.21 OWF45352.1 - 0.011 15.8 3.5 0.043 14.0 3.5 2.0 1 0 0 1 1 1 0 FYVE zinc finger zf-UBP PF02148.19 OWF45352.1 - 0.019 15.3 3.2 0.055 13.8 3.2 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Cupin_2 PF07883.11 OWF45352.1 - 0.036 13.8 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain zf-C5HC2 PF02928.16 OWF45352.1 - 0.057 13.8 7.5 0.15 12.5 7.5 1.7 1 0 0 1 1 1 0 C5HC2 zinc finger zinc-ribbon_6 PF10005.9 OWF45352.1 - 0.13 13.0 2.9 0.65 10.7 2.9 2.3 1 0 0 1 1 1 0 zinc-ribbon domain C1_2 PF03107.16 OWF45352.1 - 0.23 11.8 6.8 0.65 10.4 6.8 1.8 1 0 0 1 1 1 0 C1 domain Zn_ribbon_17 PF17120.5 OWF45352.1 - 3.6 7.3 7.3 8.8 6.0 7.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OWF45352.1 - 4.7 7.1 7.0 10 6.1 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TB2_DP1_HVA22 PF03134.19 OWF45353.1 - 1.9e-28 98.2 10.0 2.8e-28 97.6 10.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 OWF45353.1 - 0.05 13.8 3.6 0.085 13.1 3.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF2306 PF10067.9 OWF45353.1 - 0.054 13.7 1.2 0.11 12.7 1.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Arf PF00025.21 OWF45355.1 - 6.3e-37 126.7 0.0 8.7e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF45355.1 - 3.2e-12 46.7 0.0 5.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF45355.1 - 5.5e-08 32.6 0.0 8.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF45355.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF45355.1 - 5.7e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OWF45355.1 - 1.2e-06 27.9 0.2 0.00024 20.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OWF45355.1 - 3.8e-06 26.4 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 OWF45355.1 - 0.0028 17.1 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial TniB protein AAA_16 PF13191.6 OWF45355.1 - 0.011 16.2 0.0 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 OWF45355.1 - 0.014 15.1 0.1 0.028 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 OWF45355.1 - 0.03 14.5 1.0 0.062 13.4 0.2 1.9 2 1 0 2 2 2 0 Shikimate kinase AAA_22 PF13401.6 OWF45355.1 - 0.03 14.6 0.1 0.21 11.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain hSac2 PF12456.8 OWF45356.1 - 0.00098 18.8 1.3 1.4 8.7 0.1 3.9 1 1 2 4 4 4 1 Inositol phosphatase CRM1_C PF08767.11 OWF45356.1 - 0.0012 18.0 3.0 9 5.4 0.0 3.9 1 1 4 5 5 5 2 CRM1 C terminal DUF4248 PF14053.6 OWF45356.1 - 0.0071 16.3 4.8 25 5.0 0.1 4.1 2 1 0 4 4 4 0 Domain of unknown function (DUF4248) Pepsin-I3 PF06394.13 OWF45356.1 - 0.091 13.0 0.6 28 5.0 0.0 3.5 1 1 4 5 5 5 0 Pepsin inhibitor-3-like repeated domain DUF3203 PF11462.8 OWF45356.1 - 0.27 11.5 2.1 72 3.7 0.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3203) TIP39 PF14980.6 OWF45356.1 - 0.28 11.1 6.0 44 4.1 0.1 5.3 4 3 1 6 6 6 0 TIP39 peptide EF-hand_11 PF08976.11 OWF45356.1 - 0.74 10.7 2.7 21 6.0 0.1 2.8 1 1 1 3 3 3 0 EF-hand domain TCP PF03634.13 OWF45356.1 - 2.2 8.9 0.0 2.2 8.9 0.0 3.9 1 1 5 6 6 6 0 TCP family transcription factor Amastin PF07344.11 OWF45356.1 - 4 7.3 5.7 38 4.1 0.1 2.9 1 1 2 3 3 3 0 Amastin surface glycoprotein MFS_2 PF13347.6 OWF45357.1 - 2.4e-28 98.9 14.2 2.9e-27 95.3 14.2 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein zf-B_box PF00643.24 OWF45359.1 - 1.1e-11 44.7 21.6 2e-06 27.8 9.0 2.6 2 0 0 2 2 2 2 B-box zinc finger SGL PF08450.12 OWF45359.1 - 0.0088 15.6 2.4 3.6 7.1 0.0 3.6 4 0 0 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF45359.1 - 0.012 15.7 2.1 11 6.2 0.1 3.8 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.11 OWF45359.1 - 0.028 14.6 0.2 0.51 10.7 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller Mlf1IP PF10248.9 OWF45359.1 - 0.11 12.5 3.0 0.2 11.6 3.0 1.4 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF4407 PF14362.6 OWF45359.1 - 0.47 9.7 4.0 0.77 9.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med31 PF05669.12 OWF45360.1 - 5.6e-39 132.0 12.5 5.6e-39 132.0 12.5 1.4 2 0 0 2 2 2 1 SOH1 INTS2 PF14750.6 OWF45361.1 - 0 1501.7 14.2 0 1501.4 14.2 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 DUF3342 PF11822.8 OWF45362.1 - 1e-36 125.0 1.4 2.2e-36 124.0 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 OWF45362.1 - 0.0037 17.5 0.1 0.0077 16.5 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain CHORD PF04968.12 OWF45362.1 - 0.0094 16.7 6.8 0.026 15.2 6.8 1.8 1 0 0 1 1 1 1 CHORD GYF PF02213.16 OWF45363.1 - 1.1e-16 60.1 1.9 3.2e-16 58.7 1.9 1.8 1 0 0 1 1 1 1 GYF domain Phospholip_A2_2 PF05826.12 OWF45364.1 - 2e-34 117.7 7.6 3.8e-34 116.8 6.2 2.1 2 0 0 2 2 2 1 Phospholipase A2 CryBP1 PF07029.11 OWF45364.1 - 0.025 14.6 0.3 0.046 13.8 0.3 1.4 1 0 0 1 1 1 0 CryBP1 protein Redoxin PF08534.10 OWF45364.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Redoxin Phospholip_A2_1 PF00068.19 OWF45364.1 - 6.5 7.3 16.5 3.1e+02 1.9 15.2 3.0 2 1 0 2 2 2 0 Phospholipase A2 EF-hand_1 PF00036.32 OWF45366.1 - 3.6e-29 98.1 8.7 2.5e-07 29.8 1.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF45366.1 - 1.2e-28 97.2 7.2 9.2e-09 34.4 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF45366.1 - 8.6e-27 93.4 1.4 8.2e-15 55.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF45366.1 - 1.4e-22 77.6 4.1 4.1e-07 29.4 0.2 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF45366.1 - 1.4e-20 72.8 4.5 6.8e-12 45.1 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF45366.1 - 9.6e-08 32.3 0.0 0.0059 16.9 0.0 2.8 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF45366.1 - 1.7e-05 24.9 7.4 0.78 10.0 1.6 4.5 3 1 1 4 4 4 1 Dockerin type I domain EF-hand_4 PF12763.7 OWF45366.1 - 1.8e-05 24.7 0.9 0.012 15.5 0.2 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF45366.1 - 0.00094 19.5 0.0 0.0075 16.6 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain VCBS PF13517.6 OWF45366.1 - 0.0049 17.4 4.6 10 6.8 1.5 3.9 3 1 1 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_13 PF17958.1 OWF45366.1 - 0.0092 15.8 0.0 3.7 7.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain STN1_2 PF09170.10 OWF45367.1 - 5.3e-20 72.4 5.1 5.1e-18 65.9 5.1 2.3 1 1 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.25 OWF45367.1 - 1.2e-07 31.6 0.1 4.5e-07 29.8 0.1 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 OWF45367.1 - 0.0023 17.0 0.0 0.0054 15.7 0.0 1.6 1 0 0 1 1 1 1 Telomere regulation protein Stn1 PaaX PF07848.12 OWF45367.1 - 0.059 13.6 0.1 13 6.1 0.0 2.4 2 0 0 2 2 2 0 PaaX-like protein Penicillinase_R PF03965.16 OWF45367.1 - 0.088 13.2 0.8 1.2 9.6 0.1 2.4 1 1 1 2 2 2 0 Penicillinase repressor Vac_Fusion PF02346.16 OWF45367.1 - 0.15 11.7 0.6 2.6 7.7 0.4 2.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Baculo_PEP_C PF04513.12 OWF45368.1 - 0.21 11.6 16.5 14 5.7 16.5 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MSL2-CXC PF16682.5 OWF45368.1 - 0.54 10.4 25.7 20 5.4 4.2 5.8 2 2 2 4 4 4 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Baculo_PEP_C PF04513.12 OWF45369.1 - 0.0011 19.0 8.7 0.0022 18.0 8.7 1.5 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ArsR PF09824.9 OWF45369.1 - 0.084 12.5 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator DUF2465 PF10239.9 OWF45369.1 - 0.18 11.0 1.3 0.33 10.1 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2465) MSL2-CXC PF16682.5 OWF45369.1 - 1.1 9.5 5.9 11 6.3 0.2 2.5 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Baculo_PEP_C PF04513.12 OWF45370.1 - 0.002 18.2 27.9 0.12 12.4 15.6 3.8 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 OWF45370.1 - 0.026 14.2 0.5 1.9 8.2 0.0 3.1 2 2 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2465 PF10239.9 OWF45370.1 - 1.2 8.3 11.3 6.2 6.0 2.6 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2465) Cse1 PF08506.10 OWF45371.1 - 2.3e-164 546.6 7.2 4.8e-164 545.5 7.2 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 OWF45371.1 - 1.5e-162 541.2 7.8 4e-162 539.7 2.0 2.9 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus IBN_N PF03810.19 OWF45371.1 - 3.8e-13 49.1 2.9 9.3e-13 47.9 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Phyto_Pns9_10 PF05878.11 OWF45371.1 - 6.7e-05 22.2 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns9/Pns10 UME PF08064.13 OWF45371.1 - 0.0031 17.4 0.3 1.2 9.1 0.1 3.7 3 0 0 3 3 3 1 UME (NUC010) domain Xpo1 PF08389.12 OWF45371.1 - 0.0099 15.9 13.2 0.021 14.9 0.0 5.4 5 1 1 6 6 6 1 Exportin 1-like protein Cnd1 PF12717.7 OWF45371.1 - 0.26 11.3 6.2 24 4.9 0.1 5.0 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 XK-related PF09815.9 OWF45372.1 - 2.4e-59 201.1 25.4 2.8e-59 200.9 25.4 1.0 1 0 0 1 1 1 1 XK-related protein XK-related PF09815.9 OWF45373.1 - 6.4e-50 170.1 18.9 7.4e-50 169.9 18.9 1.0 1 0 0 1 1 1 1 XK-related protein GtrA PF04138.14 OWF45373.1 - 0.024 14.9 5.6 0.024 14.9 5.6 2.8 3 1 0 3 3 3 0 GtrA-like protein Paxillin PF03535.13 OWF45373.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Paxillin family DUF4386 PF14329.6 OWF45373.1 - 0.081 12.8 6.0 0.095 12.6 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) DUF2101 PF09874.9 OWF45373.1 - 0.092 12.4 9.7 0.19 11.4 9.4 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2101) S-antigen PF05756.11 OWF45373.1 - 0.98 9.8 3.4 3.4 8.1 2.1 2.6 2 0 0 2 2 2 0 S-antigen protein XK-related PF09815.9 OWF45374.1 - 2.3e-52 178.2 23.6 2.7e-52 177.9 23.6 1.0 1 0 0 1 1 1 1 XK-related protein DUF1422 PF07226.11 OWF45374.1 - 0.025 14.6 1.3 0.025 14.6 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) TMEM132D_C PF15706.5 OWF45374.1 - 0.13 12.0 0.2 0.42 10.4 0.2 1.8 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EGF PF00008.27 OWF45375.1 - 4.9e-06 26.7 7.1 1.1e-05 25.7 7.1 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 OWF45375.1 - 5.8e-05 23.6 6.8 0.00018 22.0 6.8 1.9 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_CA PF07645.15 OWF45375.1 - 0.0019 18.3 7.8 0.0045 17.2 7.8 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 OWF45375.1 - 0.027 14.7 7.3 0.055 13.7 7.3 1.6 1 0 0 1 1 1 0 EGF domain SOG2 PF10428.9 OWF45375.1 - 0.054 12.7 20.5 0.088 12.0 20.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 OWF45375.1 - 0.062 12.0 7.0 0.11 11.2 7.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EGF_2 PF07974.13 OWF45375.1 - 0.42 11.0 9.6 0.88 10.0 9.6 1.6 1 0 0 1 1 1 0 EGF-like domain Hamartin PF04388.12 OWF45375.1 - 0.45 9.1 15.5 0.79 8.3 15.5 1.3 1 0 0 1 1 1 0 Hamartin protein FXa_inhibition PF14670.6 OWF45375.1 - 0.71 10.2 5.8 1.8 8.9 5.8 1.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 OWF45375.1 - 0.8 10.1 7.3 2.5 8.5 7.3 1.9 1 0 0 1 1 1 0 Pvs28 EGF domain PRCC PF10253.9 OWF45375.1 - 0.82 10.4 11.1 1.7 9.4 11.1 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pneumo_att_G PF05539.11 OWF45375.1 - 9.3 5.7 42.1 15 5.0 42.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PAN_1 PF00024.26 OWF45376.1 - 2.4e-36 123.6 55.1 9.2e-09 35.1 5.8 5.6 5 0 0 5 5 5 5 PAN domain BRICHOS PF04089.14 OWF45376.1 - 5.2e-05 23.4 0.2 0.033 14.4 0.0 3.0 3 0 0 3 3 3 2 BRICHOS domain Phage_holin_2_4 PF16082.5 OWF45376.1 - 0.25 11.1 0.3 0.66 9.7 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ndufs5 PF10200.9 OWF45378.1 - 0.00012 22.3 0.1 0.00013 22.2 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.13 OWF45378.1 - 0.00048 20.4 0.9 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 OWF45378.1 - 0.0052 16.9 2.7 0.0094 16.1 2.7 1.4 1 1 0 1 1 1 1 CHCH domain COX6B PF02297.17 OWF45378.1 - 0.02 15.1 1.2 0.028 14.7 1.2 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 OWF45378.1 - 0.18 12.1 6.2 1.4 9.2 6.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 OWF45378.1 - 0.19 12.0 3.4 1 9.6 1.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Ras PF00071.22 OWF45380.1 - 4e-51 172.8 1.4 5.6e-51 172.4 1.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF45380.1 - 3e-32 111.4 0.5 3e-32 111.4 0.5 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF45380.1 - 1e-10 41.4 0.7 1.5e-10 40.8 0.7 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF45380.1 - 1.4e-06 28.4 0.3 2.7e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF45380.1 - 0.00069 19.6 2.0 0.23 11.4 0.2 2.5 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OWF45380.1 - 0.00074 19.1 1.2 0.0014 18.2 1.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF45380.1 - 0.0036 16.7 0.2 0.0067 15.8 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OWF45380.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OWF45380.1 - 0.16 12.3 0.0 0.28 11.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 OWF45380.1 - 0.22 11.3 3.2 0.67 9.7 0.5 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein UCH PF00443.29 OWF45381.1 - 3.5e-49 167.6 0.1 4.3e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF45381.1 - 2.3e-13 50.5 0.5 3.4e-08 33.4 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OWF45381.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family IDO PF01231.18 OWF45381.1 - 0.044 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Peptidase_C98 PF15499.6 OWF45381.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FGGY_N PF00370.21 OWF45381.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain 7tm_1 PF00001.21 OWF45382.1 - 3.7e-51 174.0 16.9 5.2e-51 173.5 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF45382.1 - 5.1e-08 32.6 18.5 8.1e-08 32.0 18.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF45382.1 - 2e-05 24.5 13.2 2e-05 24.5 13.2 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF45382.1 - 0.00075 19.2 22.1 0.0031 17.2 22.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx OppC_N PF12911.7 OWF45382.1 - 0.032 14.2 0.1 0.032 14.2 0.1 3.4 5 1 0 5 5 5 0 N-terminal TM domain of oligopeptide transport permease C Curlin_rpt PF07012.12 OWF45383.1 - 0.0046 16.9 29.5 2 8.5 0.4 6.8 2 1 4 7 7 7 4 Curlin associated repeat DUF725 PF05267.12 OWF45383.1 - 0.031 14.3 6.2 0.031 14.3 6.2 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF725) DUF4111 PF13427.6 OWF45383.1 - 0.17 12.0 0.1 1.4 9.1 0.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4111) Mucin-like PF16058.5 OWF45383.1 - 1.7 8.8 18.6 0.27 11.3 8.9 2.3 1 1 2 3 3 3 0 Mucin-like PRP21_like_P PF12230.8 OWF45384.1 - 0.32 10.8 6.2 0.35 10.7 6.2 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein VWA PF00092.28 OWF45385.1 - 0.0014 18.9 0.1 0.0017 18.7 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF45385.1 - 0.0015 19.2 0.1 0.0018 18.9 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Chromo PF00385.24 OWF45385.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Pribosyltran PF00156.27 OWF45386.1 - 8.3e-24 83.9 0.0 1.3e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OWF45386.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase INSIG PF07281.12 OWF45387.1 - 5.8e-44 150.3 10.1 5.1e-43 147.2 10.1 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF4064 PF13273.6 OWF45387.1 - 0.015 15.6 0.2 0.015 15.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF202 PF02656.15 OWF45387.1 - 0.11 12.9 0.8 0.11 12.9 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2632 PF10943.8 OWF45387.1 - 0.13 11.8 2.3 0.28 10.7 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2632) KOG2701 PF09762.9 OWF45388.1 - 4.4e-76 255.0 0.0 4.4e-76 255.0 0.0 4.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein (DUF2037) Baculo_PEP_C PF04513.12 OWF45388.1 - 4.2 7.4 7.9 7.6 6.6 4.7 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PulA_N1 PF17999.1 OWF45389.1 - 1.1 10.1 7.1 0.82 10.4 2.0 3.0 2 1 0 2 2 2 0 Pullulanase N1-terminal domain DUF948 PF06103.11 OWF45389.1 - 1.8 8.9 8.8 1.7 9.0 0.4 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) C1q PF00386.21 OWF45390.1 - 3.9e-24 85.3 0.7 3.9e-24 85.3 0.7 1.9 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF45390.1 - 0.0013 18.6 0.2 0.0021 18.0 0.2 1.3 1 0 0 1 1 1 1 BclA C-terminal domain MCC-bdg_PDZ PF10506.9 OWF45390.1 - 0.017 15.1 1.7 0.029 14.4 1.7 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GIT_CC PF16559.5 OWF45390.1 - 0.034 14.0 0.9 0.05 13.5 0.2 1.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor NRBF2 PF08961.10 OWF45390.1 - 0.095 12.3 0.9 0.14 11.7 0.9 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF948 PF06103.11 OWF45390.1 - 0.14 12.5 1.0 0.26 11.5 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 OWF45390.1 - 0.15 12.7 2.4 0.23 12.1 1.2 1.8 1 1 1 2 2 2 0 SlyX Gal_Lectin PF02140.18 OWF45391.1 - 1.2e-18 67.3 1.0 1.2e-18 67.3 1.0 3.9 2 1 2 4 4 4 1 Galactose binding lectin domain CBM_14 PF01607.24 OWF45391.1 - 6.9e-09 35.7 34.1 6.8e-06 26.2 8.3 4.4 3 1 1 4 4 4 3 Chitin binding Peritrophin-A domain SAWADEE PF16719.5 OWF45391.1 - 0.058 13.4 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 SAWADEE domain GAS PF13851.6 OWF45392.1 - 0.0024 17.2 10.4 0.003 17.0 10.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF1192 PF06698.11 OWF45392.1 - 0.0027 17.7 8.0 0.0089 16.1 0.5 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1192) Atg14 PF10186.9 OWF45392.1 - 0.006 15.7 13.5 0.0069 15.5 13.5 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CALCOCO1 PF07888.11 OWF45392.1 - 0.011 14.6 17.4 0.013 14.4 17.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.19 OWF45392.1 - 0.016 15.0 18.0 0.021 14.6 18.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TRAF_BIRC3_bd PF16673.5 OWF45392.1 - 0.025 14.3 11.9 0.026 14.3 3.4 2.7 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 OWF45392.1 - 0.03 13.2 16.4 0.031 13.2 15.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 OWF45392.1 - 0.039 13.7 3.1 0.039 13.7 3.1 2.4 1 1 1 2 2 2 0 Septum formation initiator CENP-Q PF13094.6 OWF45392.1 - 0.087 13.0 17.4 8.2 6.6 17.4 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ABC_tran_CTD PF16326.5 OWF45392.1 - 0.11 12.8 14.7 0.99 9.7 10.3 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 OWF45392.1 - 0.18 12.5 11.7 2.1 9.0 2.6 2.6 1 1 1 2 2 2 0 SlyX Fmp27_WPPW PF10359.9 OWF45392.1 - 0.19 10.6 15.1 0.24 10.2 15.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4795 PF16043.5 OWF45392.1 - 0.24 11.0 14.5 0.024 14.2 10.3 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4795) LPP PF04728.13 OWF45392.1 - 0.28 11.6 3.8 8.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 OWF45392.1 - 0.29 11.3 22.0 0.023 14.8 16.1 2.0 2 0 0 2 2 2 0 Tropomyosin like TSC22 PF01166.18 OWF45392.1 - 0.34 11.3 7.9 4.9 7.5 1.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family HIP1_clath_bdg PF16515.5 OWF45392.1 - 0.35 11.5 17.4 0.44 11.2 9.6 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 OWF45392.1 - 0.41 10.8 10.9 2.2 8.4 4.9 2.4 1 1 0 2 2 2 0 TolA binding protein trimerisation Fez1 PF06818.15 OWF45392.1 - 0.49 10.8 19.0 0.24 11.8 14.0 2.0 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 OWF45392.1 - 0.51 10.9 18.7 0.48 10.9 17.8 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region HemX PF04375.14 OWF45392.1 - 0.6 9.3 13.5 0.16 11.2 10.3 1.6 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Pox_A21 PF05323.12 OWF45392.1 - 0.62 10.7 3.2 0.95 10.1 0.8 2.0 1 1 1 2 2 2 0 Poxvirus A21 Protein DUF724 PF05266.14 OWF45392.1 - 0.63 9.8 14.4 0.46 10.3 12.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Herpes_UL6 PF01763.16 OWF45392.1 - 0.91 8.0 12.7 0.054 12.0 4.4 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like Phlebovirus_NSM PF07246.11 OWF45392.1 - 0.93 8.8 12.8 0.47 9.8 11.0 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMF_DNA_bd PF12329.8 OWF45392.1 - 2 8.5 20.9 1.8 8.6 7.6 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Synaptobrevin PF00957.21 OWF45392.1 - 2.1 8.2 6.3 0.72 9.7 3.2 1.8 2 0 0 2 2 2 0 Synaptobrevin GrpE PF01025.19 OWF45392.1 - 2.5 7.8 15.5 2.3e+02 1.4 15.5 2.2 1 1 0 1 1 1 0 GrpE RNase_HII PF01351.18 OWF45392.1 - 2.6 7.8 7.0 0.7 9.7 2.4 1.9 1 1 1 2 2 2 0 Ribonuclease HII Seryl_tRNA_N PF02403.22 OWF45392.1 - 2.7 8.3 12.6 3.4 7.9 1.1 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CLZ PF16526.5 OWF45392.1 - 3 8.3 12.7 3.1 8.2 1.7 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlxA PF14282.6 OWF45392.1 - 3 7.9 18.6 0.96 9.5 5.1 2.7 1 1 1 2 2 2 0 FlxA-like protein Ax_dynein_light PF10211.9 OWF45392.1 - 3.2 7.6 17.5 4.2 7.3 8.6 2.3 1 1 2 3 3 3 0 Axonemal dynein light chain DUF641 PF04859.12 OWF45392.1 - 3.3 8.1 14.7 9.8 6.5 14.7 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) EMP24_GP25L PF01105.24 OWF45392.1 - 3.6 7.5 9.6 0.35 10.8 4.2 1.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.19 OWF45392.1 - 3.9 5.3 15.1 4.5 5.1 15.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 OWF45392.1 - 4.5 7.5 18.9 0.84 9.9 13.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 OWF45392.1 - 6.1 7.3 8.6 6.8 7.2 3.0 2.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Swi5 PF07061.11 OWF45392.1 - 6.2 7.0 10.8 8.7 6.5 3.5 2.7 1 1 1 2 2 2 0 Swi5 DUF2680 PF10925.8 OWF45392.1 - 6.4 6.9 8.8 15 5.7 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Spc24 PF08286.11 OWF45392.1 - 8.3 6.7 16.8 3.1 8.1 7.0 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF5320 PF17253.2 OWF45392.1 - 9.2 7.4 9.2 0.43 11.7 1.3 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) ANAPC4_WD40 PF12894.7 OWF45393.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 OWF45394.1 - 5.3e-07 29.6 11.2 5.3e-07 29.6 11.2 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF45394.1 - 5.6e-06 26.1 10.0 5.6e-06 26.1 10.0 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF45394.1 - 7.6e-06 26.2 10.3 7.6e-06 26.2 10.3 3.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF45394.1 - 0.00019 21.2 10.2 0.00019 21.2 10.2 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF45394.1 - 0.00021 21.4 11.3 0.00021 21.4 11.3 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF45394.1 - 0.0053 16.7 11.1 0.0053 16.7 11.1 3.3 3 2 0 3 3 3 1 zinc-RING finger domain IBR PF01485.21 OWF45394.1 - 0.027 14.7 5.9 0.027 14.7 5.9 3.1 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-ANAPC11 PF12861.7 OWF45394.1 - 4.8 7.3 16.7 0.53 10.4 2.5 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OWF45395.1 - 1.5e-06 28.2 8.3 4.6e-06 26.6 8.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF45395.1 - 7.9e-05 22.4 9.5 7.9e-05 22.4 9.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF45395.1 - 0.00011 22.5 12.1 0.00011 22.5 12.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OWF45395.1 - 0.00075 19.4 9.8 0.00075 19.4 9.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF45395.1 - 0.0037 17.1 9.6 0.0037 17.1 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CCDC53 PF10152.9 OWF45395.1 - 1.1 9.6 3.8 4.9 7.5 3.8 1.9 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex zf-B_box PF00643.24 OWF45395.1 - 3.8 7.8 25.0 0.039 14.1 9.8 3.2 2 1 0 2 2 2 0 B-box zinc finger Gal_Lectin PF02140.18 OWF45396.1 - 7.9e-13 48.7 1.0 7.9e-13 48.7 1.0 3.6 2 1 2 4 4 4 1 Galactose binding lectin domain CBM_14 PF01607.24 OWF45396.1 - 4.2e-12 46.0 34.4 3.6e-07 30.2 7.3 3.9 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain MHC_I_3 PF16497.5 OWF45396.1 - 0.062 12.8 0.2 1.3 8.4 0.0 2.2 1 1 1 2 2 2 0 MHC-I family domain CUB PF00431.20 OWF45397.1 - 2.6e-18 66.4 0.0 1.4e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 OWF45397.1 - 0.091 12.5 0.1 1.2 8.9 0.0 2.6 2 1 1 3 3 3 0 CUB-like domain DAG1 PF05454.11 OWF45397.1 - 0.12 11.8 0.4 0.2 11.0 0.4 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CBM_14 PF01607.24 OWF45398.1 - 3.9e-13 49.4 29.7 4.3e-07 30.0 5.9 3.4 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain An_peroxidase PF03098.15 OWF45399.1 - 1.4e-97 327.5 0.0 2.9e-93 313.3 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase VWD PF00094.25 OWF45401.1 - 1.6e-65 220.2 7.9 1.2e-27 97.2 0.0 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 OWF45401.1 - 1.2e-31 108.9 38.3 1.8e-16 60.3 12.2 8.4 9 1 2 11 11 11 3 C8 domain Ldl_recept_a PF00057.18 OWF45401.1 - 1.3e-24 86.1 62.9 4e-09 36.5 6.0 12.6 14 0 0 14 14 14 4 Low-density lipoprotein receptor domain class A TIL PF01826.17 OWF45401.1 - 4.5e-22 78.0 85.5 1.1e-10 41.6 18.5 14.9 12 2 1 13 13 13 4 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 OWF45401.1 - 0.00097 19.4 4.9 0.00097 19.4 4.9 17.6 8 5 4 13 13 13 2 von Willebrand factor type C domain Fringe PF02434.16 OWF45402.1 - 0.0029 17.1 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Fringe-like BTB_3 PF16017.5 OWF45402.1 - 0.091 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 BTB/POZ domain LRRFIP PF09738.9 OWF45404.1 - 2.5e-72 243.9 48.4 2.5e-72 243.9 48.4 2.9 2 1 0 2 2 2 1 LRRFIP family DUF3450 PF11932.8 OWF45404.1 - 0.0025 17.2 10.9 0.0025 17.2 10.9 4.4 3 1 2 5 5 5 1 Protein of unknown function (DUF3450) SOGA PF11365.8 OWF45404.1 - 0.0056 17.8 6.3 0.0056 17.8 6.3 5.2 2 2 3 5 5 3 1 Protein SOGA BLOC1_2 PF10046.9 OWF45404.1 - 0.011 16.0 1.1 0.011 16.0 1.1 5.9 4 2 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Surfac_D-trimer PF09006.11 OWF45404.1 - 0.012 15.5 2.0 0.32 10.9 0.0 3.3 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation TPR_MLP1_2 PF07926.12 OWF45404.1 - 0.018 15.1 17.2 0.018 15.1 17.2 4.6 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 OWF45404.1 - 0.02 14.9 3.3 0.02 14.9 3.3 4.9 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Med10 PF09748.9 OWF45404.1 - 0.041 13.8 13.8 3.2 7.7 0.4 4.7 3 1 1 4 4 4 0 Transcription factor subunit Med10 of Mediator complex Glutaredoxin PF00462.24 OWF45404.1 - 0.53 10.6 3.3 1.5 9.1 0.0 3.2 3 0 0 3 3 3 0 Glutaredoxin NPV_P10 PF05531.12 OWF45404.1 - 2.5 8.6 12.4 0.24 11.9 1.9 3.7 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Dehydrin PF00257.19 OWF45404.1 - 2.9 8.4 10.8 0.26 11.8 5.9 1.8 2 0 0 2 2 2 0 Dehydrin Baculo_PEP_C PF04513.12 OWF45404.1 - 3.4 7.7 10.3 4.1 7.5 3.3 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_25 PF13649.6 OWF45405.1 - 2e-07 31.6 0.0 3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF45405.1 - 0.00031 21.3 0.0 0.00044 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 OWF45405.1 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_12 PF08242.12 OWF45405.1 - 0.007 17.1 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF45405.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OWF45405.1 - 0.034 13.9 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 OWF45405.1 - 0.044 12.9 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.18 OWF45405.1 - 0.055 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 OWF45405.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 OWF45405.1 - 0.19 10.8 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Neur_chan_LBD PF02931.23 OWF45406.1 - 5.6e-30 104.4 0.6 9.1e-30 103.7 0.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45406.1 - 3.3e-14 53.5 10.3 6e-12 46.1 5.4 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF45407.1 - 6.9e-38 130.3 0.0 9.3e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45407.1 - 2e-06 28.1 13.6 2e-06 28.1 13.6 1.9 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.9 OWF45407.1 - 1.7 6.9 10.3 2.9 6.1 10.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DAGK_cat PF00781.24 OWF45408.1 - 1.7e-21 76.1 1.1 3.4e-21 75.2 0.3 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Peptidase_C48 PF02902.19 OWF45409.1 - 5e-47 160.5 0.3 5e-47 160.5 0.3 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 OWF45409.1 - 0.0028 16.4 3.9 0.024 13.4 0.9 2.5 2 1 0 2 2 2 1 Vaccinia virus I7 processing peptidase adh_short PF00106.25 OWF45410.1 - 2.7e-24 85.7 0.1 5.5e-13 48.8 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF45410.1 - 2e-11 43.9 0.0 0.00022 20.9 0.0 2.3 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF45410.1 - 1.4e-07 31.6 0.1 3.3e-07 30.4 0.1 1.6 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 OWF45410.1 - 0.16 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OWF45410.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fibrinogen_C PF00147.18 OWF45411.1 - 1.2e-41 143.0 2.2 1.2e-41 143.0 2.2 1.6 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain EF-hand_1 PF00036.32 OWF45413.1 - 9.8e-19 65.5 8.2 3.5e-06 26.2 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF45413.1 - 2.7e-17 63.0 14.0 2.1e-13 50.5 3.3 3.3 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF45413.1 - 2e-16 58.6 5.2 0.00017 20.9 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF45413.1 - 2.7e-14 51.8 8.2 3.1e-05 23.6 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF45413.1 - 1.2e-09 37.8 13.4 0.021 14.7 0.7 4.3 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF45413.1 - 0.00011 22.5 5.7 0.31 11.4 0.2 3.7 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region GPP34 PF05719.11 OWF45413.1 - 0.06 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) DUF3683 PF12447.8 OWF45413.1 - 0.51 10.5 2.6 8.1 6.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) NMT_C PF02799.15 OWF45414.1 - 1.6e-78 263.0 0.0 3.2e-78 262.1 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OWF45414.1 - 1.1e-72 243.1 0.0 6.5e-72 240.6 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OWF45414.1 - 0.0013 18.8 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF45414.1 - 0.0015 18.8 0.0 0.0058 16.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family TFIIF_alpha PF05793.12 OWF45414.1 - 2.3 6.7 17.9 2.9 6.4 17.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PXA PF02194.15 OWF45415.1 - 3.3e-50 170.6 5.4 1.1e-49 168.8 0.7 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 OWF45415.1 - 1.6e-28 99.5 0.3 1.8e-27 96.1 0.0 3.0 3 1 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 OWF45415.1 - 6e-21 74.5 0.4 1.8e-20 73.0 0.4 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 OWF45415.1 - 1.8e-19 70.2 1.5 2.3e-18 66.6 0.7 3.0 3 0 0 3 3 3 1 Regulator of G protein signaling domain GerD PF17898.1 OWF45415.1 - 0.21 11.6 1.5 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 Spore germination GerD central core domain Helicase_C_2 PF13307.6 OWF45416.1 - 1.2e-57 194.8 0.5 2.8e-57 193.6 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OWF45416.1 - 4.1e-50 169.8 0.4 4.1e-50 169.8 0.4 2.1 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 OWF45416.1 - 0.0067 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_11 PF13086.6 OWF45416.1 - 0.19 11.5 14.2 0.55 10.0 14.0 2.0 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 OWF45417.1 - 1.7e-69 234.0 0.0 2.3e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF45417.1 - 6.6e-29 101.1 0.0 9.8e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF45417.1 - 5.2e-06 26.0 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like fn3 PF00041.21 OWF45417.1 - 0.00022 21.5 0.0 0.00081 19.7 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain GAPT PF11770.8 OWF45417.1 - 0.048 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) VSP PF03302.13 OWF45417.1 - 0.063 12.1 0.6 0.099 11.5 0.6 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein MRJP PF03022.16 OWF45418.1 - 6e-42 144.0 0.5 9.5e-42 143.3 0.5 1.3 1 0 0 1 1 1 1 Major royal jelly protein MRJP PF03022.16 OWF45420.1 - 3.2e-42 144.8 0.1 5.1e-42 144.2 0.1 1.3 1 0 0 1 1 1 1 Major royal jelly protein MRJP PF03022.16 OWF45421.1 - 6e-39 134.1 0.0 1.1e-38 133.3 0.0 1.4 1 0 0 1 1 1 1 Major royal jelly protein MRJP PF03022.16 OWF45422.1 - 1.3e-42 146.1 0.1 1.9e-42 145.6 0.1 1.2 1 0 0 1 1 1 1 Major royal jelly protein MRJP PF03022.16 OWF45424.1 - 1.3e-37 129.7 0.3 2e-37 129.1 0.3 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 OWF45424.1 - 0.00063 19.4 0.6 0.12 11.9 0.0 3.6 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OWF45424.1 - 0.039 14.2 0.1 0.52 10.5 0.1 2.6 2 0 0 2 2 2 0 Arylesterase MRJP PF03022.16 OWF45425.1 - 3.1e-41 141.6 0.1 4.8e-41 141.0 0.1 1.2 1 0 0 1 1 1 1 Major royal jelly protein Arylesterase PF01731.20 OWF45425.1 - 0.17 12.1 0.9 3 8.1 0.0 3.1 4 0 0 4 4 4 0 Arylesterase Calx-beta PF03160.14 OWF45426.1 - 2.2e-35 120.8 7.6 6.8e-18 64.7 0.1 3.0 3 0 0 3 3 3 2 Calx-beta domain Calx-beta PF03160.14 OWF45427.1 - 5.8e-36 122.7 0.1 7e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 Calx-beta domain DUF4397 PF14344.6 OWF45427.1 - 0.15 12.9 5.4 0.99 10.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4397) Pur_ac_phosph_N PF16656.5 OWF45427.1 - 0.37 11.4 4.6 13 6.4 0.2 2.3 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Big_1 PF02369.16 OWF45427.1 - 8.3 6.5 21.7 0.43 10.6 2.9 4.5 2 2 2 4 4 4 0 Bacterial Ig-like domain (group 1) BTB_2 PF02214.22 OWF45428.1 - 1.2e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OWF45428.1 - 0.017 15.2 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 BTB/POZ domain RNA_helicase PF00910.22 OWF45429.1 - 0.00038 20.8 1.8 0.00078 19.8 0.0 2.4 3 0 0 3 3 3 1 RNA helicase DUF3047 PF11249.8 OWF45429.1 - 0.043 13.3 0.5 0.25 10.8 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3047) zinc-ribbons_6 PF07191.12 OWF45429.1 - 0.24 11.4 8.9 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbons SAM35 PF10806.8 OWF45430.1 - 0.065 13.5 0.0 0.076 13.3 0.0 1.1 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex Peptidase_M28 PF04389.17 OWF45431.1 - 2.5e-21 76.3 0.0 7.3e-21 74.8 0.0 1.8 2 1 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.15 OWF45431.1 - 4.4e-19 68.8 0.0 1.2e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 OWF45431.1 - 1.2e-10 41.3 0.0 3.2e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 OWF45431.1 - 0.073 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Roc PF08477.13 OWF45431.1 - 0.13 12.4 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4731 PF15875.5 OWF45431.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) Arf PF00025.21 OWF45432.1 - 7.7e-55 185.0 0.0 9e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OWF45432.1 - 2.8e-13 49.8 0.0 3.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF45432.1 - 1.1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OWF45432.1 - 0.00012 21.4 0.3 0.36 10.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OWF45432.1 - 0.00026 20.5 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 OWF45432.1 - 0.0023 18.5 0.1 0.014 16.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 OWF45432.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF45432.1 - 0.035 14.2 0.0 0.069 13.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OWF45432.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain Galactosyl_T PF01762.21 OWF45433.1 - 2.9e-42 144.7 0.6 2.9e-42 144.7 0.6 2.1 2 1 0 2 2 2 1 Galactosyltransferase zf-CCHC PF00098.23 OWF45434.1 - 3.3e-16 58.5 28.4 1.4e-06 28.1 0.7 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 OWF45434.1 - 2.4e-05 24.0 20.3 0.031 14.0 0.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 OWF45434.1 - 0.00039 20.2 21.9 0.03 14.1 1.0 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 OWF45434.1 - 0.31 11.0 24.9 2.3 8.2 2.4 4.5 4 1 1 5 5 5 0 Zinc knuckle 7tm_1 PF00001.21 OWF45435.1 - 5.1e-21 75.2 3.5 5.1e-21 75.2 3.5 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF45435.1 - 8.3e-05 22.4 8.4 0.011 15.5 5.1 2.4 2 1 0 2 2 2 2 Olfactory receptor Ilm1 PF10311.9 OWF45435.1 - 0.066 12.9 1.4 0.9 9.2 1.2 2.5 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 7tm_1 PF00001.21 OWF45436.1 - 1e-23 84.0 3.0 1e-23 84.0 3.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF45436.1 - 5.9e-07 29.5 7.8 1.6e-05 24.8 3.4 2.3 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF45436.1 - 0.026 13.9 12.0 0.011 15.2 7.3 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF45437.1 - 1.7e-20 73.5 15.5 4.5e-20 72.1 12.2 2.0 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF45437.1 - 0.0041 16.5 9.7 0.0041 16.5 9.7 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ras PF00071.22 OWF45438.1 - 1.5e-30 105.9 0.0 1.8e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF45438.1 - 7.3e-12 45.6 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF45438.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family KRTDAP PF15200.6 OWF45439.1 - 0.0016 18.2 0.0 40 4.1 0.0 4.3 5 0 0 5 5 5 0 Keratinocyte differentiation-associated PAC2 PF09754.9 OWF45439.1 - 0.013 15.5 0.0 6.4 6.7 0.0 2.4 1 1 1 2 2 2 0 PAC2 family ArabFuran-catal PF09206.11 OWF45439.1 - 0.026 13.8 0.4 3 7.1 0.1 2.4 1 1 0 2 2 2 0 Alpha-L-arabinofuranosidase B, catalytic JAB PF01398.21 OWF45439.1 - 0.037 14.0 15.7 4.2 7.4 0.1 4.5 1 1 4 5 5 5 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NSP11 PF06471.12 OWF45439.1 - 0.05 12.1 0.1 7.1 5.0 0.0 2.9 1 1 1 2 2 2 0 NSP11 RNA_pol_Rpb2_45 PF10385.9 OWF45439.1 - 0.13 12.6 0.0 1.2e+02 3.1 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase beta subunit external 1 domain Tna_leader PF08053.11 OWF45440.1 - 0.45 10.6 4.9 6.4 6.9 0.0 4.5 6 2 1 7 7 7 0 Tryptophanase operon leader peptide Calx-beta PF03160.14 OWF45441.1 - 1.2e-57 192.3 6.0 2.7e-29 101.3 0.5 2.8 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 OWF45441.1 - 2.7e-51 173.5 34.6 9.6e-28 97.0 12.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 OWF45441.1 - 3.3e-33 114.8 4.8 6e-33 114.0 4.8 1.4 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain DUF4843 PF16132.5 OWF45441.1 - 0.011 15.4 0.0 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) Pro_racemase PF05544.11 OWF45442.1 - 4.3e-38 131.2 0.0 5.1e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Proline racemase Pro_racemase PF05544.11 OWF45443.1 - 0.00026 20.1 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 Proline racemase Pro_racemase PF05544.11 OWF45444.1 - 1.5e-93 313.4 0.0 1.8e-93 313.2 0.0 1.0 1 0 0 1 1 1 1 Proline racemase DAP_epimerase PF01678.19 OWF45444.1 - 0.041 14.0 0.1 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Diaminopimelate epimerase Thump_like PF18096.1 OWF45444.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 THUMP domain-like PhzC-PhzF PF02567.16 OWF45444.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein GpcrRhopsn4 PF10192.9 OWF45445.1 - 1.5e-59 201.5 22.1 2.2e-59 200.9 22.1 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 OWF45445.1 - 3.4e-05 23.2 20.4 6e-05 22.4 20.4 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor Tcf25 PF04910.14 OWF45445.1 - 0.073 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Transcriptional repressor TCF25 BRF1 PF07741.13 OWF45446.1 - 3.2e-24 85.2 10.1 3.2e-24 85.2 10.1 2.5 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TFIIB PF00382.19 OWF45446.1 - 4.7e-17 61.8 0.0 8.5e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat PHR PF08005.12 OWF45447.1 - 8.5e-46 156.4 1.8 1.5e-45 155.6 1.8 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 OWF45447.1 - 1.8e-22 79.6 0.1 1.5e-21 76.7 0.0 2.4 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 OWF45447.1 - 6.5e-08 32.6 1.3 1.5e-07 31.4 0.4 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 OWF45447.1 - 0.0026 17.8 0.1 0.007 16.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4082) BET PF17035.5 OWF45447.1 - 0.16 12.2 0.1 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation TF_Zn_Ribbon PF08271.12 OWF45448.1 - 1.3e-12 47.0 3.1 2.2e-12 46.3 3.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 OWF45448.1 - 3e-10 40.0 0.1 4.5e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_N PF00134.23 OWF45448.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-ribbon_3 PF13248.6 OWF45448.1 - 0.03 13.7 6.9 0.067 12.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RB_B PF01857.20 OWF45448.1 - 0.032 14.3 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain OrfB_Zn_ribbon PF07282.11 OWF45448.1 - 0.038 13.9 1.8 0.084 12.8 1.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 OWF45448.1 - 0.25 11.1 5.0 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 OWF45448.1 - 1.6 8.5 6.1 14 5.5 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 OWF45448.1 - 3.2 8.1 7.3 1.7e+02 2.6 1.8 2.7 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase DUF4508 PF14969.6 OWF45449.1 - 6e-33 113.0 2.3 6.9e-33 112.8 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) DUF2158 PF09926.9 OWF45449.1 - 0.28 10.9 2.1 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) C2 PF00168.30 OWF45450.1 - 7.8e-41 138.5 0.5 7.1e-23 80.9 0.2 3.9 4 0 0 4 4 4 2 C2 domain BROMI PF14961.6 OWF45450.1 - 0.0054 14.2 0.1 0.0077 13.7 0.1 1.1 1 0 0 1 1 1 1 Broad-minded protein SMP_LBD PF17047.5 OWF45450.1 - 0.22 11.0 1.1 17 4.8 0.3 2.4 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain DUF4033 PF13225.6 OWF45451.1 - 7.9 6.6 31.3 1.7 8.7 0.4 6.7 1 1 6 8 8 8 0 Domain of unknown function (DUF4033) Forkhead PF00250.18 OWF45452.1 - 1.4e-39 134.2 0.0 2.2e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Ribonuclease_T2 PF00445.18 OWF45453.1 - 1.6e-50 171.9 1.3 2e-50 171.6 1.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family RNase_P_Rpp14 PF01900.19 OWF45453.1 - 0.0097 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Ribonuclease_T2 PF00445.18 OWF45454.1 - 3e-55 187.3 0.7 3.6e-55 187.0 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family CBM53 PF16760.5 OWF45454.1 - 0.074 13.6 0.2 0.27 11.9 0.0 2.0 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) Ribonuclease_T2 PF00445.18 OWF45455.1 - 6.1e-51 173.2 4.3 7.5e-51 173.0 4.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Ribonuclease_T2 PF00445.18 OWF45456.1 - 9.8e-55 185.6 0.7 1.2e-54 185.3 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Kunitz_BPTI PF00014.23 OWF45457.1 - 5e-17 61.9 6.1 7.4e-17 61.3 6.1 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WD40 PF00400.32 OWF45458.1 - 4.4e-26 90.6 13.7 1.9e-06 28.5 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OWF45458.1 - 9.2e-05 21.6 0.4 0.4 9.6 0.1 3.7 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OWF45458.1 - 0.00024 21.3 0.5 2.3 8.6 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Claudin_2 PF13903.6 OWF45459.1 - 1.6 8.4 10.2 0.032 14.0 3.3 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Sod_Cu PF00080.20 OWF45460.1 - 4.1e-22 78.9 0.9 6.1e-22 78.3 0.9 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 OWF45460.1 - 6.2e-13 49.0 0.8 6.2e-13 49.0 0.8 2.5 3 0 0 3 3 3 1 Heavy-metal-associated domain BON PF04972.17 OWF45460.1 - 0.016 15.5 0.9 0.046 14.0 0.6 1.9 1 1 0 1 1 1 0 BON domain zf-HC5HC2H PF13771.6 OWF45461.1 - 7.4e-17 61.4 0.6 7.4e-17 61.4 0.6 5.0 5 0 0 5 5 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OWF45461.1 - 1.4e-06 28.5 2.7 1.4e-06 28.5 2.7 4.0 4 1 1 5 5 5 1 PHD-zinc-finger like domain zf-RING_11 PF17123.5 OWF45461.1 - 5.1 6.9 11.6 0.067 12.9 1.7 2.8 2 0 0 2 2 2 0 RING-like zinc finger HARP PF07443.13 OWF45462.1 - 0.015 14.9 0.1 59 3.4 0.0 3.8 1 1 3 4 4 4 0 HepA-related protein (HARP) DUF3463 PF11946.8 OWF45462.1 - 0.02 14.7 0.4 13 5.6 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3463) Sharpin_PH PF16764.5 OWF45462.1 - 0.092 12.5 0.6 8.9 6.1 0.0 2.8 1 1 2 3 3 3 0 Sharpin PH domain SAD_SRA PF02182.17 OWF45462.1 - 0.19 11.4 5.4 2.4 7.8 0.3 3.3 1 1 2 3 3 3 0 SAD/SRA domain DUF4913 PF16259.5 OWF45462.1 - 0.28 11.3 9.6 7.9 6.6 0.1 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4913) F-box-like PF12937.7 OWF45462.1 - 0.71 9.8 5.7 35 4.4 0.1 3.3 3 0 0 3 3 3 0 F-box-like Peptidase_M28 PF04389.17 OWF45462.1 - 2.5 7.7 10.3 1e+03 -0.7 10.3 3.0 1 1 0 1 1 1 0 Peptidase family M28 YedD PF13987.6 OWF45462.1 - 6.3 6.7 5.8 76 3.2 0.1 3.2 2 1 1 3 3 3 0 YedD-like protein DUF3463 PF11946.8 OWF45463.1 - 0.00013 21.8 6.6 33 4.3 0.0 7.1 1 1 6 8 8 8 0 Domain of unknown function (DUF3463) Sharpin_PH PF16764.5 OWF45463.1 - 0.03 14.1 4.8 30 4.4 0.0 5.1 1 1 6 7 7 7 0 Sharpin PH domain DUF2737 PF10930.8 OWF45463.1 - 0.17 11.5 4.6 3e+02 1.1 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF2737) PH_17 PF18012.1 OWF45463.1 - 0.19 11.4 10.2 9.1 6.1 0.1 5.5 2 2 4 7 7 7 0 PH domain DUF446 PF04287.12 OWF45463.1 - 0.56 10.3 2.4 74 3.5 0.0 3.7 2 2 2 5 5 5 0 tRNA pseudouridine synthase C DUF4913 PF16259.5 OWF45463.1 - 1.1 9.3 30.7 20 5.3 0.1 8.2 1 1 8 9 9 9 0 Domain of unknown function (DUF4913) Ras PF00071.22 OWF45464.1 - 4.3e-35 120.7 0.1 7e-35 120.0 0.1 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF45464.1 - 4.6e-14 52.7 0.0 8.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OWF45464.1 - 0.00028 20.5 0.3 0.00045 19.8 0.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF45464.1 - 0.00053 19.9 0.1 0.54 10.2 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase AFG1_ATPase PF03969.16 OWF45464.1 - 0.13 11.2 0.0 0.31 9.9 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase zf-RING_2 PF13639.6 OWF45465.1 - 1.9e-09 37.7 12.5 3.4e-09 36.9 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OWF45465.1 - 2.2e-07 31.0 12.8 8.3e-07 29.2 12.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF45465.1 - 2e-05 24.4 12.5 3.4e-05 23.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF45465.1 - 3.6e-05 23.5 12.1 6.5e-05 22.7 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OWF45465.1 - 4.5e-05 23.0 5.6 8.8e-05 22.1 5.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OWF45465.1 - 0.00013 21.8 8.4 0.00025 20.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF45465.1 - 0.0003 20.7 8.2 0.00062 19.7 8.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 OWF45465.1 - 0.0047 17.1 4.9 0.011 15.9 4.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 OWF45465.1 - 0.0071 16.6 3.4 0.018 15.3 3.4 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_5 PF14634.6 OWF45465.1 - 0.0077 16.2 10.9 0.022 14.7 11.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF45465.1 - 0.014 15.4 8.5 0.26 11.4 8.5 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OWF45465.1 - 0.022 14.6 7.8 0.04 13.8 7.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 OWF45465.1 - 0.2 12.0 10.7 0.34 11.3 10.7 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 OWF45465.1 - 0.32 10.8 11.5 0.06 13.1 7.8 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 OWF45465.1 - 1.7 8.8 7.0 3.3 7.8 7.0 1.5 1 0 0 1 1 1 0 Zinc-finger DUF2427 PF10348.9 OWF45465.1 - 2.3 8.1 9.9 0.042 13.6 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) RINGv PF12906.7 OWF45465.1 - 3.5 7.8 10.3 8.1 6.7 10.3 1.5 1 0 0 1 1 1 0 RING-variant domain Prenyltrans PF00432.21 OWF45466.1 - 5.3e-13 48.5 0.2 1.8e-09 37.2 0.4 2.5 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat HECT PF00632.25 OWF45467.1 - 2.4e-08 33.8 0.0 7.7e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Neur_chan_LBD PF02931.23 OWF45468.1 - 1.6e-47 161.7 0.1 2.2e-47 161.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45468.1 - 3.5e-14 53.4 5.7 3.5e-14 53.4 5.7 2.1 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF3377 PF11857.8 OWF45468.1 - 0.9 9.5 6.6 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) 7tm_1 PF00001.21 OWF45469.1 - 2.8e-62 210.4 22.5 3.6e-62 210.1 22.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF45469.1 - 4.4e-15 55.8 22.8 6.2e-15 55.3 22.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF45469.1 - 1.4e-05 25.0 17.5 2.3e-05 24.3 17.5 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF45469.1 - 5.9e-05 22.8 18.4 5.9e-05 22.8 18.4 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2116 PF09889.9 OWF45469.1 - 5.1 7.2 10.7 18 5.4 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4573 PF15140.6 OWF45470.1 - 0.0028 17.5 5.2 0.0033 17.3 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) DUF4592 PF15262.6 OWF45470.1 - 0.028 15.1 3.3 0.5 11.1 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4592) FAM165 PF14981.6 OWF45470.1 - 0.7 9.7 5.7 34 4.4 0.5 3.8 1 1 2 3 3 3 0 FAM165 family GCV_T_C PF08669.11 OWF45470.1 - 1.3 9.0 6.4 37 4.3 0.6 3.4 1 1 1 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain DUF1388 PF07142.12 OWF45470.1 - 1.3 9.0 10.2 1.4e+02 2.5 0.0 5.7 7 0 0 7 7 7 0 Repeat of unknown function (DUF1388) DUF3215 PF11503.8 OWF45471.1 - 0.00017 21.3 34.4 15 5.5 0.3 10.0 1 1 13 14 14 14 10 Protein of unknown function (DUF3215) DUF4024 PF13216.6 OWF45471.1 - 0.02 14.8 4.5 45 4.1 0.0 8.2 12 5 2 14 14 14 0 Protein of unknown function (DUF4024) MspA PF09203.11 OWF45472.1 - 0.0028 17.5 6.5 0.48 10.3 2.3 3.1 1 1 1 2 2 2 1 MspA KRTAP PF11759.8 OWF45472.1 - 0.031 14.8 19.6 3.3e+03 -1.3 19.6 3.9 1 1 0 1 1 1 0 Keratin-associated matrix DUF3309 PF11752.8 OWF45472.1 - 3.8 7.6 42.7 8.3 6.6 0.4 8.4 2 2 6 8 8 8 0 Protein of unknown function (DUF3309) DUF2816 PF10992.8 OWF45472.1 - 4 7.4 33.2 14 5.6 0.2 5.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2816) Mucin-like PF16058.5 OWF45473.1 - 0.097 12.8 9.8 0.34 11.0 0.0 2.8 1 1 2 3 3 3 0 Mucin-like ubiquitin PF00240.23 OWF45474.1 - 8.4e-14 51.1 0.4 2.1e-13 49.8 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OWF45474.1 - 0.00013 22.4 0.3 0.0012 19.2 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OWF45474.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain UPF0728 PF15092.6 OWF45475.1 - 1.4e-32 111.3 0.0 1.6e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 Nfu_N PF08712.11 OWF45476.1 - 1.6e-31 108.2 0.0 2.7e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OWF45476.1 - 2.9e-25 88.2 0.1 4.8e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Thioredoxin_8 PF13905.6 OWF45477.1 - 4.1e-22 78.3 0.0 5.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OWF45477.1 - 8.2e-09 35.4 0.0 1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 OWF45477.1 - 1.5e-07 31.4 0.0 8.4e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 OWF45477.1 - 2e-07 30.8 0.1 3.6e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 OWF45477.1 - 0.0001 22.7 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OWF45477.1 - 0.08 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like NusA_N PF08529.11 OWF45477.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 NusA N-terminal domain Thioredoxin_9 PF14595.6 OWF45477.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin AAA_33 PF13671.6 OWF45478.1 - 6.1e-23 81.6 0.0 1.5e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 OWF45478.1 - 1.6e-13 50.8 0.1 1.6e-13 50.8 0.1 2.2 2 0 0 2 2 2 1 SPRY domain AAA_18 PF13238.6 OWF45478.1 - 1.4e-05 25.6 1.0 2.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Astacin PF01400.24 OWF45479.1 - 5.9e-55 185.9 0.5 1.1e-54 185.0 0.4 1.5 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) MAM PF00629.23 OWF45479.1 - 4e-33 114.6 10.2 5.1e-27 94.8 1.7 2.5 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Sushi PF00084.20 OWF45479.1 - 1.7e-10 41.4 0.1 1.7e-10 41.4 0.1 2.5 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) Astacin PF01400.24 OWF45480.1 - 2e-43 148.2 2.5 2.9e-43 147.7 2.5 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) lci PF12197.8 OWF45480.1 - 0.17 11.7 0.4 4.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein Peptidase_M10 PF00413.24 OWF45480.1 - 3.1 7.6 6.0 49 3.7 0.0 2.8 2 1 0 2 2 2 0 Matrixin eIF-3_zeta PF05091.12 OWF45481.1 - 2.7e-214 713.0 1.6 3.2e-214 712.7 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DNA_pol_B_3 PF08408.10 OWF45481.1 - 0.03 14.5 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase family B viral insert NARG2_C PF10505.9 OWF45481.1 - 0.091 12.3 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Alpha_L_fucos PF01120.17 OWF45483.1 - 1.8e-121 405.9 10.3 2.3e-121 405.6 10.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF45483.1 - 3.7e-28 97.9 0.2 7.3e-28 97.0 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 OWF45483.1 - 0.088 12.9 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator 7tm_1 PF00001.21 OWF45484.1 - 3.2e-56 190.6 15.2 5e-56 189.9 15.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF45484.1 - 5.4e-12 45.6 14.6 7.9e-12 45.1 14.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srh PF10318.9 OWF45484.1 - 0.00015 20.9 12.2 0.00015 20.9 12.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srw PF10324.9 OWF45484.1 - 0.0025 17.2 13.7 0.014 14.7 13.7 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Pro_isomerase PF00160.21 OWF45485.1 - 4.6e-45 153.7 0.0 5.3e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 OWF45486.1 - 1e-43 149.3 0.1 1.2e-43 149.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PTS_2-RNA PF01885.16 OWF45487.1 - 9.4e-20 71.4 0.0 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Pro_isomerase PF00160.21 OWF45488.1 - 5.1e-45 153.6 0.2 6.3e-45 153.3 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD His_Phos_2 PF00328.22 OWF45489.1 - 1.1e-28 100.7 0.1 2.3e-28 99.7 0.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CENP-B_dimeris PF09026.10 OWF45489.1 - 0.0049 17.2 1.7 0.0049 17.2 1.7 1.9 2 0 0 2 2 2 1 Centromere protein B dimerisation domain DUF4708 PF15813.5 OWF45489.1 - 0.056 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) IKBKB_SDD PF18397.1 OWF45490.1 - 4.5e-75 252.5 4.6 7.5e-75 251.8 4.6 1.3 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 OWF45490.1 - 7.8e-54 182.8 0.0 3.8e-53 180.5 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF45490.1 - 1.2e-35 123.0 0.0 3.8e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF45490.1 - 0.00048 19.5 0.0 0.0061 15.9 0.1 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OWF45490.1 - 0.00085 18.7 0.1 0.0045 16.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL_2 PF13472.6 OWF45491.1 - 3.2e-07 30.9 0.1 5.9e-07 30.1 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF45491.1 - 0.00037 20.5 0.1 0.00051 20.1 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RRM_1 PF00076.22 OWF45492.1 - 6.2e-10 38.7 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF45492.1 - 5e-05 22.9 0.1 9.7e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PXA PF02194.15 OWF45493.1 - 5.5e-23 81.9 3.9 5.5e-23 81.9 3.9 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 OWF45493.1 - 4.3e-17 62.7 0.2 1.4e-16 61.1 0.2 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 OWF45493.1 - 7.5e-15 54.9 3.7 1.7e-14 53.8 1.5 2.5 2 0 0 2 2 2 1 PX domain Myosin_head PF00063.21 OWF45494.1 - 1.1e-203 678.2 0.3 1.7e-203 677.6 0.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 OWF45494.1 - 5.6e-57 193.1 0.0 1.1e-56 192.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain IQ PF00612.27 OWF45494.1 - 1.5e-45 148.7 107.9 1.2e-05 24.7 0.5 18.0 18 0 0 18 18 18 15 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 OWF45494.1 - 3.1e-40 138.1 0.0 7.2e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_22 PF13401.6 OWF45494.1 - 0.00037 20.8 0.2 0.0026 18.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Haspin_kinase PF12330.8 OWF45494.1 - 0.0029 16.6 0.5 0.0079 15.2 0.5 1.7 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF45494.1 - 0.0059 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC_tran PF00005.27 OWF45494.1 - 0.085 13.4 0.1 0.43 11.1 0.1 2.3 1 0 0 1 1 1 0 ABC transporter PDZ_5 PF17817.1 OWF45495.1 - 1.4e-27 95.8 1.0 1.4e-27 95.8 1.0 3.0 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 OWF45495.1 - 1.7e-14 53.7 0.1 3.6e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 OWF45495.1 - 6.2e-13 48.9 0.8 1.4e-12 47.8 0.8 1.6 1 0 0 1 1 1 1 PDZ domain SAM_1 PF00536.30 OWF45495.1 - 4.6e-09 36.6 0.3 1.1e-08 35.4 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 OWF45495.1 - 0.12 12.2 0.3 0.91 9.4 0.0 2.6 3 0 0 3 3 3 0 PDZ domain zf-C2H2_4 PF13894.6 OWF45496.1 - 0.051 14.4 1.5 0.12 13.3 1.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DnaJ PF00226.31 OWF45497.1 - 2.6e-17 62.7 1.0 4.2e-17 62.0 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain TM2 PF05154.16 OWF45497.1 - 4.1e-11 43.0 14.2 4.1e-11 43.0 14.2 2.6 2 0 0 2 2 2 1 TM2 domain DUF2232 PF09991.9 OWF45497.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ras PF00071.22 OWF45498.1 - 6.5e-43 146.1 0.1 7.6e-43 145.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF45498.1 - 2.3e-23 82.7 0.0 3.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF45498.1 - 1.9e-11 43.7 0.1 2.4e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF45498.1 - 0.00012 22.1 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF45498.1 - 0.0018 17.8 0.1 0.0039 16.7 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OWF45498.1 - 0.032 13.6 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2852 PF11014.8 OWF45500.1 - 0.055 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4538 PF15061.6 OWF45501.1 - 9 6.1 22.5 2.5 7.9 1.6 4.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4538) Lipase_GDSL_2 PF13472.6 OWF45502.1 - 1.3e-07 32.2 0.0 1.6e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF16 PF01519.16 OWF45503.1 - 4.8e-10 39.9 230.0 10 6.7 17.9 11.8 1 1 3 4 4 4 1 Protein of unknown function DUF16 MCPsignal PF00015.21 OWF45503.1 - 2.6e-09 37.1 150.5 1.4 8.7 9.3 10.3 1 1 6 9 9 9 9 Methyl-accepting chemotaxis protein (MCP) signalling domain Exonuc_VII_L PF02601.15 OWF45503.1 - 0.0014 18.3 143.2 5.7 6.4 16.8 7.4 1 1 1 2 2 2 1 Exonuclease VII, large subunit PAPA-1 PF04795.12 OWF45503.1 - 0.0015 19.3 167.3 61 4.5 1.7 26.5 1 1 13 14 14 14 0 PAPA-1-like conserved region Suppressor_APC PF11414.8 OWF45503.1 - 0.0068 16.4 145.3 14 5.8 2.0 18.2 1 1 30 31 31 31 2 Adenomatous polyposis coli tumour suppressor protein DUF3552 PF12072.8 OWF45503.1 - 0.083 12.3 203.2 14 5.1 13.1 11.8 1 1 11 14 14 14 0 Domain of unknown function (DUF3552) DUF745 PF05335.13 OWF45503.1 - 0.18 11.5 157.2 7.3 6.3 11.0 9.6 1 1 5 7 7 7 0 Protein of unknown function (DUF745) Imm51 PF15595.6 OWF45503.1 - 0.42 10.6 82.3 90 3.1 0.3 20.0 1 1 52 53 53 53 0 Immunity protein 51 APG17 PF04108.12 OWF45503.1 - 3.2 6.8 169.4 1.8e+04 -103.9 169.4 5.5 1 1 0 1 1 1 0 Autophagy protein Apg17 MFS_1 PF07690.16 OWF45504.1 - 5.2e-10 38.8 11.5 8.5e-10 38.1 11.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.13 OWF45504.1 - 0.014 15.7 5.7 0.014 15.7 5.7 3.4 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) DUF2561 PF10812.8 OWF45504.1 - 0.15 12.1 0.4 0.43 10.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) TSP_1 PF00090.19 OWF45506.1 - 2.9e-28 97.8 104.4 5.5e-08 32.9 9.7 9.2 8 1 0 8 8 8 6 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 OWF45506.1 - 1.2e-20 73.6 0.0 2.3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.11 OWF45506.1 - 2.2e-08 34.7 12.4 1.2e-07 32.3 12.4 2.5 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain NPR1_interact PF15699.5 OWF45506.1 - 0.84 10.3 4.4 1.6 9.4 4.4 1.3 1 0 0 1 1 1 0 NPR1 interacting Pentapeptide_2 PF01469.18 OWF45506.1 - 4.2 7.3 32.0 16 5.4 20.7 2.6 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) Fibrinogen_C PF00147.18 OWF45507.1 - 2e-38 132.4 2.5 2e-38 132.4 2.5 1.6 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAX PF00292.18 OWF45508.1 - 1.2e-66 222.3 0.3 2.7e-66 221.2 0.2 1.6 2 0 0 2 2 2 1 'Paired box' domain HTH_23 PF13384.6 OWF45508.1 - 7.4e-07 28.8 0.0 2.2e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 OWF45508.1 - 2.6e-05 24.8 0.0 0.00084 19.9 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 OWF45508.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 OWF45508.1 - 0.0034 17.5 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 OWF45508.1 - 0.82 9.5 2.8 1.3 8.9 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain CARD PF00619.21 OWF45509.1 - 1e-26 92.8 3.8 6e-16 58.3 0.0 3.7 4 0 0 4 4 4 2 Caspase recruitment domain CARD_2 PF16739.5 OWF45509.1 - 1.5e-08 34.5 0.4 0.00067 19.6 0.0 2.8 2 0 0 2 2 2 2 Caspase recruitment domain FliS PF02561.14 OWF45509.1 - 0.0053 17.0 0.7 0.019 15.2 0.1 2.3 2 0 0 2 2 2 1 Flagellar protein FliS TPR_2 PF07719.17 OWF45510.1 - 0.023 14.8 4.1 0.063 13.4 1.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Gly_acyl_tr_N PF06021.11 OWF45510.1 - 0.13 12.4 0.7 0.28 11.2 0.2 1.8 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase TPR_1 PF00515.28 OWF45510.1 - 1.6 8.7 5.1 70 3.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CARD PF00619.21 OWF45511.1 - 1.5e-26 92.2 2.5 1e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 Caspase recruitment domain CARD_2 PF16739.5 OWF45511.1 - 2.7e-08 33.7 0.2 6.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Caspase recruitment domain OprF PF05736.11 OWF45511.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 OprF membrane domain FAD_binding_3 PF01494.19 OWF45512.1 - 0.0061 15.8 0.0 0.5 9.6 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 OWF45512.1 - 0.019 14.2 0.0 0.044 13.0 0.0 1.5 2 0 0 2 2 2 0 Thi4 family DUF5380 PF17351.2 OWF45512.1 - 0.21 11.5 0.6 0.47 10.3 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5380) TRC8_N PF13705.6 OWF45513.1 - 5.8e-116 388.3 46.0 6.7e-116 388.1 46.0 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 OWF45513.1 - 2.1e-10 40.7 7.0 4.6e-10 39.7 7.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF45513.1 - 4.1e-10 39.3 6.1 8.5e-10 38.3 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF45513.1 - 1.1e-08 35.2 4.5 3.1e-08 33.8 4.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF45513.1 - 3.3e-07 30.0 6.1 9.8e-07 28.6 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF45513.1 - 4e-07 29.8 4.1 8.9e-07 28.7 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45513.1 - 6.2e-07 29.2 3.1 1.5e-06 27.9 3.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF45513.1 - 5.6e-06 26.2 6.1 1.1e-05 25.3 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF45513.1 - 7.6e-06 25.9 2.6 2e-05 24.6 2.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OWF45513.1 - 0.00023 21.1 7.1 0.00057 19.9 7.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OWF45513.1 - 0.00047 19.9 2.2 0.0012 18.5 2.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger RINGv PF12906.7 OWF45513.1 - 0.026 14.6 3.8 0.061 13.5 3.8 1.7 1 0 0 1 1 1 0 RING-variant domain TackOD1 PF18551.1 OWF45513.1 - 0.046 13.4 0.4 0.078 12.6 0.4 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Zn_ribbon_17 PF17120.5 OWF45513.1 - 0.066 12.8 4.1 0.2 11.3 4.1 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 OWF45513.1 - 0.18 11.7 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 OWF45513.1 - 0.54 10.5 6.7 7.2 6.9 6.7 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OWF45513.1 - 1.5 9.0 7.1 4.3 7.6 7.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 OWF45513.1 - 4.9 6.9 6.4 30 4.4 6.5 2.1 1 1 1 2 2 2 0 P-11 zinc finger TRC8_N PF13705.6 OWF45514.1 - 7.7e-150 500.1 42.3 8.9e-150 499.9 42.3 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-C3HC4_2 PF13923.6 OWF45514.1 - 2.4e-10 40.1 5.6 5.9e-10 38.8 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF45514.1 - 3.8e-09 36.7 5.5 9.4e-09 35.5 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OWF45514.1 - 8.7e-08 32.3 6.5 3.4e-07 30.4 6.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF45514.1 - 3.8e-06 26.7 6.2 8.7e-06 25.5 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF45514.1 - 3.2e-05 23.7 5.0 6.1e-05 22.8 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45514.1 - 0.0001 22.1 3.9 0.00034 20.4 3.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF45514.1 - 0.00019 21.1 2.9 0.00062 19.5 2.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OWF45514.1 - 0.00027 20.8 6.2 0.00057 19.8 6.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF45514.1 - 0.0017 18.4 4.1 0.0047 16.9 4.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF45514.1 - 0.015 15.3 4.6 0.015 15.3 4.6 2.2 2 1 1 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OWF45514.1 - 0.04 13.5 4.9 0.089 12.4 4.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OWF45514.1 - 0.14 12.4 6.2 0.6 10.3 6.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 OWF45514.1 - 0.5 10.5 3.5 0.47 10.6 1.8 1.8 2 0 0 2 2 1 0 KIAA1045 RING finger zf-P11 PF03854.14 OWF45514.1 - 0.77 9.5 10.2 0.26 11.0 6.7 2.1 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.7 OWF45514.1 - 1.6 9.0 6.3 3.8 7.7 6.3 1.7 1 0 0 1 1 1 0 RING-variant domain YwiC PF14256.6 OWF45514.1 - 10 6.5 16.2 2.5 8.4 4.4 3.1 2 0 0 2 2 2 0 YwiC-like protein VWD PF00094.25 OWF45515.1 - 2e-100 333.6 70.0 3.4e-14 53.4 1.9 11.6 11 0 0 11 11 11 9 von Willebrand factor type D domain PAN_1 PF00024.26 OWF45515.1 - 2.5e-23 81.8 23.6 5.5e-07 29.4 0.0 6.6 6 0 0 6 6 6 4 PAN domain EGF_2 PF07974.13 OWF45515.1 - 2.7e-06 27.6 237.5 0.0018 18.6 9.1 15.6 15 0 0 15 15 15 9 EGF-like domain EGF_Tenascin PF18720.1 OWF45515.1 - 0.00013 21.9 144.0 0.022 14.8 10.6 11.2 9 0 0 9 9 9 8 Tenascin EGF domain EphA2_TM PF14575.6 OWF45515.1 - 0.11 13.4 0.0 0.28 12.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AAA PF00004.29 OWF45516.1 - 2.2e-05 24.9 4.4 0.011 16.2 0.1 4.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF45516.1 - 0.00059 19.8 0.0 0.0067 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF45516.1 - 0.0018 18.5 0.1 0.23 11.7 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OWF45516.1 - 0.0026 17.3 0.3 0.18 11.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Prok-RING_4 PF14447.6 OWF45516.1 - 0.011 15.6 17.6 0.0031 17.3 8.5 3.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ABC_tran PF00005.27 OWF45516.1 - 0.039 14.5 0.0 0.3 11.6 0.0 2.6 1 0 0 1 1 1 0 ABC transporter DUF1493 PF07377.12 OWF45516.1 - 0.097 13.1 0.0 0.73 10.3 0.0 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Sigma54_activat PF00158.26 OWF45516.1 - 0.11 12.2 0.5 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain zf-BED PF02892.15 OWF45516.1 - 0.23 11.5 3.4 0.71 9.9 0.2 3.4 3 0 0 3 3 2 0 BED zinc finger zf-RING_4 PF14570.6 OWF45516.1 - 3 7.7 20.3 0.0043 16.8 3.4 4.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OWF45516.1 - 3.3 8.0 10.3 26 5.1 10.3 2.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF45516.1 - 4.5 7.2 28.0 0.029 14.2 8.7 3.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OWF45516.1 - 8.5 6.5 39.1 0.09 12.8 4.8 5.3 4 1 1 5 5 5 0 Double zinc ribbon tRNA_edit PF04073.15 OWF45517.1 - 1.4e-22 80.1 0.0 1.6e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Peptidase_M28 PF04389.17 OWF45518.1 - 6.8e-23 81.4 0.0 1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OWF45518.1 - 1.4e-06 28.2 0.2 1.3e-05 25.0 0.1 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 PA PF02225.22 OWF45518.1 - 0.0018 18.3 0.1 0.0045 17.0 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M1 PF01433.20 OWF45519.1 - 6.7e-48 163.1 2.8 7.9e-48 162.9 1.7 1.6 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OWF45519.1 - 1.1e-23 84.4 0.2 1.5e-23 83.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF4886 PF16227.5 OWF45519.1 - 0.041 13.1 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Peptidase_MA_2 PF13485.6 OWF45519.1 - 0.072 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase MA superfamily ERAP1_C PF11838.8 OWF45520.1 - 1.6e-63 215.2 0.3 2.4e-63 214.6 0.3 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OWF45520.1 - 9.2e-23 80.9 0.1 1.6e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain BTB PF00651.31 OWF45521.1 - 1.2e-20 73.8 2.4 1.2e-20 73.8 0.7 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF45521.1 - 2.4e-16 59.7 3.7 9.5e-15 54.6 0.7 2.7 3 0 0 3 3 3 2 BTB And C-terminal Kelch Antimicrobial22 PF16047.5 OWF45522.1 - 1.2e-18 66.5 21.4 0.075 12.9 0.2 8.9 9 0 0 9 9 9 6 Frog antimicrobial peptide CholecysA-Rec_N PF09193.10 OWF45522.1 - 2.5e-07 30.6 14.9 2.7 8.0 0.3 7.7 1 1 9 10 10 10 5 Cholecystokinin A receptor, N-terminal Ntox35 PF15534.6 OWF45522.1 - 2e-06 28.2 1.5 2.1 8.9 0.0 5.3 2 1 5 7 7 7 1 Bacterial toxin 35 Cyt-b5 PF00173.28 OWF45522.1 - 0.00016 21.8 0.0 3.7 7.7 0.0 4.3 1 1 1 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain EIIBC-GUT_C PF07663.11 OWF45522.1 - 0.00067 19.8 4.7 4.9 7.4 0.2 3.8 1 1 5 6 6 6 2 Sorbitol phosphotransferase enzyme II C-terminus MIP-T3_C PF17749.1 OWF45522.1 - 0.0058 16.6 2.3 7.5 6.5 0.1 3.2 1 1 5 6 6 6 1 Microtubule-binding protein MIP-T3 C-terminal region DUF1474 PF07342.11 OWF45522.1 - 0.0077 16.7 0.5 1.3e+02 3.2 0.0 4.2 1 1 7 8 8 8 0 Protein of unknown function (DUF1474) Syntaxin_2 PF14523.6 OWF45522.1 - 0.015 15.6 4.0 0.46 10.9 0.6 2.1 1 1 1 2 2 2 0 Syntaxin-like protein DUF3231 PF11553.8 OWF45522.1 - 0.15 11.7 0.7 55 3.4 0.0 3.2 1 1 5 6 6 6 0 Protein of unknown function (DUF3231) RuBisCO_large_N PF02788.16 OWF45522.1 - 0.18 12.0 9.8 54 4.0 0.1 5.7 1 1 3 4 4 4 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain HTH_45 PF14947.6 OWF45522.1 - 0.31 11.0 6.1 2.1 8.4 0.1 3.4 1 1 2 4 4 4 0 Winged helix-turn-helix DASH_Dad1 PF08649.10 OWF45522.1 - 1.1 9.5 3.8 49 4.2 0.2 3.1 1 1 4 5 5 5 0 DASH complex subunit Dad1 BIR PF00653.21 OWF45524.1 - 2.2e-30 105.1 10.2 1.3e-16 60.9 0.2 3.2 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF45524.1 - 3.6e-10 39.5 12.7 3.6e-10 39.5 12.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45524.1 - 0.0013 18.6 12.1 0.0013 18.6 12.1 3.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF45524.1 - 0.64 10.4 13.4 3.1 8.2 13.4 2.3 1 0 0 1 1 1 0 Ring finger domain TFIID-18kDa PF02269.16 OWF45526.1 - 3.6e-36 123.0 0.4 4.5e-36 122.8 0.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit LMSTEN PF07988.12 OWF45526.1 - 0.064 12.7 0.9 0.14 11.6 0.9 1.6 1 0 0 1 1 1 0 LMSTEN motif COX17 PF05051.13 OWF45527.1 - 3.5e-21 75.3 7.0 4.1e-21 75.1 7.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DnaJ_C PF01556.18 OWF45528.1 - 8.8e-43 145.9 0.1 1.2e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OWF45528.1 - 1.4e-23 82.7 2.8 2.3e-23 82.1 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain ASH PF15780.5 OWF45529.1 - 3e-35 120.4 8.1 0.00031 20.9 0.0 15.0 17 0 0 17 17 17 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 OWF45529.1 - 9.5e-18 64.2 10.3 0.003 17.8 0.0 8.6 10 0 0 10 10 10 4 Transmembrane protein 131-like Motile_Sperm PF00635.26 OWF45529.1 - 5.6e-11 42.3 5.2 0.075 12.9 0.3 9.5 9 0 0 9 9 9 1 MSP (Major sperm protein) domain PapD-like PF14874.6 OWF45529.1 - 5.2e-07 29.8 4.9 0.019 15.1 0.3 5.4 5 0 0 5 5 5 2 Flagellar-associated PapD-like CH PF00307.31 OWF45529.1 - 5.3e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Transglut_C PF00927.22 OWF45529.1 - 7.1e-05 22.9 3.9 1.2 9.3 0.0 6.5 8 0 0 8 8 8 1 Transglutaminase family, C-terminal ig like domain SRP40_C PF05022.12 OWF45530.1 - 8.2e-29 100.3 3.2 8e-28 97.1 3.2 3.0 1 0 0 1 1 1 1 SRP40, C-terminal domain GCV_T PF01571.21 OWF45531.1 - 1.9e-08 34.0 0.0 2.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain PapC_C PF13953.6 OWF45531.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 PapC C-terminal domain Prenyltransf PF01255.19 OWF45532.1 - 4.4e-09 36.2 0.1 8.6e-09 35.2 0.1 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase BIR PF00653.21 OWF45533.1 - 6.5e-32 110.0 14.9 7e-19 68.3 0.3 3.4 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF45533.1 - 5.2e-11 42.2 9.5 5.2e-11 42.2 9.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45533.1 - 0.0016 18.3 10.1 0.0044 16.9 10.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.9 OWF45533.1 - 1.6 9.1 7.4 10 6.5 5.7 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) PDEase_I PF00233.19 OWF45534.1 - 1.6e-63 214.6 3.0 1.1e-60 205.3 0.2 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Staphylcoagulse PF04022.12 OWF45534.1 - 0.013 15.0 0.1 0.036 13.6 0.1 1.8 1 0 0 1 1 1 0 Staphylocoagulase repeat HS1_rep PF02218.15 OWF45535.1 - 2.1e-137 447.1 86.7 8.4e-21 74.0 5.4 8.6 8 0 0 8 8 8 8 Repeat in HS1/Cortactin SH3_9 PF14604.6 OWF45535.1 - 4.5e-19 68.0 0.1 9.5e-19 67.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF45535.1 - 8.4e-18 63.7 0.2 8.4e-18 63.7 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OWF45535.1 - 4.1e-10 39.2 0.0 7.5e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 OWF45535.1 - 4.8e-08 33.4 11.1 7.5 7.0 0.0 7.3 1 1 5 7 7 7 4 TMEM210 family DUF4192 PF13830.6 OWF45535.1 - 3.8 7.5 5.7 5.8 6.9 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CppA_C PF14507.6 OWF45536.1 - 0.4 11.4 16.8 3.4 8.4 1.4 4.7 1 1 2 3 3 3 0 CppA C-terminal DUF5635 PF18685.1 OWF45537.1 - 0.025 14.5 2.9 1.3 9.0 0.1 3.7 1 1 4 5 5 5 0 Family of unknown function (DUF5635) Reg_prop PF07494.11 OWF45537.1 - 0.09 13.0 1.9 33 5.2 0.0 4.4 4 1 1 5 5 5 0 Two component regulator propeller FAM220 PF15487.6 OWF45537.1 - 0.23 11.0 0.8 4.1 7.0 0.1 2.0 1 1 1 2 2 2 0 FAM220 family LURAP PF14854.6 OWF45537.1 - 0.25 11.3 2.2 1.4e+02 2.4 0.0 4.2 1 1 4 5 5 5 0 Leucine rich adaptor protein SDF PF00375.18 OWF45538.1 - 1e-126 423.1 29.4 1.2e-126 422.8 29.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2207 PF09972.9 OWF45538.1 - 0.31 9.8 3.1 0.38 9.5 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) 7tm_1 PF00001.21 OWF45539.1 - 2.9e-27 95.7 23.8 4.3e-27 95.1 23.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Phospholip_A2_1 PF00068.19 OWF45540.1 - 7.5e-21 74.7 20.6 9.5e-21 74.4 20.6 1.1 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 OWF45540.1 - 0.0091 16.2 20.1 6.1 7.1 20.1 2.5 1 1 0 1 1 1 1 Phospholipase A2 PLA2G12 PF06951.11 OWF45540.1 - 7.6 6.4 19.8 1.8e+04 -5.8 19.8 2.3 1 1 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) RsgA_GTPase PF03193.16 OWF45541.1 - 0.00052 20.0 0.0 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OWF45541.1 - 0.0018 18.4 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OWF45541.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.13 OWF45541.1 - 0.0022 17.2 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AIG1 PF04548.16 OWF45541.1 - 0.0035 16.7 0.1 0.0072 15.7 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 OWF45541.1 - 0.0042 16.4 0.0 0.0085 15.4 0.0 1.5 1 1 0 1 1 1 1 Septin AAA_7 PF12775.7 OWF45541.1 - 0.0097 15.4 0.0 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 OWF45541.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OWF45541.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 OWF45541.1 - 0.032 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 OWF45541.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF45541.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 OWF45542.1 - 2.6e-36 124.7 0.0 3.3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF45542.1 - 1.5e-11 44.6 0.0 2.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF45542.1 - 5.9e-05 22.6 0.0 7.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF45542.1 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF45542.1 - 0.0024 17.8 0.0 0.28 11.1 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 OWF45542.1 - 0.0056 17.2 0.0 0.0098 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF45542.1 - 0.018 15.3 0.1 0.27 11.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 OWF45542.1 - 0.053 13.8 0.4 0.18 12.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 OWF45542.1 - 0.067 12.7 0.0 0.61 9.6 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.20 OWF45542.1 - 0.069 12.3 0.6 7.6 5.6 0.2 2.6 1 1 0 2 2 2 0 G-protein alpha subunit MIT_C PF16565.5 OWF45542.1 - 0.082 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT AAA PF00004.29 OWF45542.1 - 0.088 13.2 0.0 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF45542.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain UPF0220 PF05255.11 OWF45543.1 - 1.5e-44 151.5 3.4 1.6e-44 151.4 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DHHC PF01529.20 OWF45543.1 - 0.79 9.8 3.8 0.36 10.9 1.1 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase GCFC PF07842.12 OWF45544.1 - 2.3e-31 109.4 1.5 7.5e-31 107.8 0.4 2.3 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein UPF0242 PF06785.11 OWF45544.1 - 0.00013 22.1 0.3 0.00013 22.1 0.3 4.5 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus MG4 PF17789.1 OWF45544.1 - 0.2 11.8 1.5 0.98 9.6 0.0 2.4 2 0 0 2 2 2 0 Macroglobulin domain MG4 AAA_5 PF07728.14 OWF45545.1 - 1.6e-123 407.2 0.0 2.3e-23 82.7 0.0 8.8 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OWF45545.1 - 4.9e-54 181.0 0.1 1.6e-19 70.0 0.0 7.1 7 0 0 7 7 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 OWF45545.1 - 3.3e-31 107.5 0.0 1.5e-30 105.4 0.0 2.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 OWF45545.1 - 7.4e-29 100.2 0.0 1.3e-09 38.0 0.0 6.9 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 OWF45545.1 - 5.2e-27 94.9 2.1 3.2e-05 24.4 0.0 7.9 8 0 0 8 8 6 6 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OWF45545.1 - 7.1e-26 90.8 2.9 2.6e-05 23.8 0.0 6.7 6 0 0 6 6 6 5 P-loop containing dynein motor region Dynein_heavy PF03028.15 OWF45545.1 - 4.2e-24 84.9 0.0 4.6e-05 23.5 0.0 7.5 6 0 0 6 6 6 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 OWF45545.1 - 5.9e-24 85.3 10.7 0.011 16.2 0.1 8.4 6 1 0 6 6 6 6 AAA ATPase domain Sigma54_activat PF00158.26 OWF45545.1 - 1.7e-16 60.4 1.8 0.093 12.4 0.0 6.6 7 0 0 7 7 6 5 Sigma-54 interaction domain AAA_22 PF13401.6 OWF45545.1 - 2.9e-16 60.0 10.6 0.003 17.8 0.0 8.5 8 0 0 8 8 7 4 AAA domain TsaE PF02367.17 OWF45545.1 - 3.3e-16 59.4 4.0 0.012 15.6 0.0 6.7 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OWF45545.1 - 1.1e-15 58.4 4.3 0.057 13.9 0.0 8.0 6 0 0 6 6 6 3 ABC transporter AAA_6 PF12774.7 OWF45545.1 - 5.5e-15 55.2 0.2 0.027 13.5 0.0 8.6 8 0 0 8 8 8 2 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 OWF45545.1 - 1.1e-14 54.6 0.0 0.017 15.1 0.0 7.4 7 0 0 7 7 7 3 AAA domain Sigma54_activ_2 PF14532.6 OWF45545.1 - 2.5e-14 53.6 1.3 0.00063 19.9 0.0 6.4 6 0 0 6 6 6 3 Sigma-54 interaction domain NACHT PF05729.12 OWF45545.1 - 1.4e-12 47.8 5.9 0.2 11.6 0.0 7.2 6 0 0 6 6 6 3 NACHT domain AAA_18 PF13238.6 OWF45545.1 - 7.7e-11 42.7 9.2 0.33 11.5 0.0 8.1 7 0 0 7 7 6 1 AAA domain DUF815 PF05673.13 OWF45545.1 - 9.8e-10 38.0 1.1 0.063 12.4 0.0 5.9 6 0 0 6 6 6 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 OWF45545.1 - 3.6e-09 36.9 2.2 2.3 8.4 0.0 6.8 6 0 0 6 6 6 2 AAA domain PduV-EutP PF10662.9 OWF45545.1 - 8.7e-08 32.0 4.4 0.42 10.4 0.0 5.8 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 OWF45545.1 - 9e-08 31.7 8.8 0.62 9.4 0.1 8.2 8 1 1 9 9 8 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OWF45545.1 - 1.3e-07 31.6 1.0 2.3 7.9 0.0 5.8 5 0 0 5 5 5 1 IstB-like ATP binding protein RNA_helicase PF00910.22 OWF45545.1 - 1.6e-07 31.7 7.4 8 6.9 0.0 7.7 7 0 0 7 7 7 0 RNA helicase RuvB_N PF05496.12 OWF45545.1 - 1.8e-07 31.1 4.2 2.2 8.0 0.0 7.0 8 0 0 8 8 6 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 OWF45545.1 - 5.2e-07 29.7 6.9 6.2 6.7 0.0 6.6 6 0 0 6 6 6 0 RsgA GTPase VWA PF00092.28 OWF45545.1 - 6.9e-07 29.7 0.2 4.9e-06 26.9 0.1 2.6 2 0 0 2 2 1 1 von Willebrand factor type A domain AAA_28 PF13521.6 OWF45545.1 - 7.2e-07 29.6 6.6 2.1 8.6 0.0 6.8 6 0 0 6 6 6 1 AAA domain AAA_19 PF13245.6 OWF45545.1 - 7.4e-07 29.6 7.7 6 7.2 0.0 7.0 6 0 0 6 6 5 0 AAA domain T2SSE PF00437.20 OWF45545.1 - 2e-06 27.1 2.7 1.7 7.7 0.0 6.0 6 0 0 6 6 6 1 Type II/IV secretion system protein Roc PF08477.13 OWF45545.1 - 2.3e-06 27.8 4.1 43 4.3 0.0 6.8 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 OWF45545.1 - 3.1e-06 27.3 5.0 6.7 6.6 0.0 5.8 5 0 0 5 5 5 0 Rad17 P-loop domain AAA_8 PF12780.7 OWF45545.1 - 1.6e-05 24.3 8.0 0.78 9.0 0.0 6.4 8 0 0 8 8 6 1 P-loop containing dynein motor region D4 VWA_2 PF13519.6 OWF45545.1 - 2.2e-05 25.1 1.0 0.00064 20.3 0.2 3.7 2 1 0 3 3 2 1 von Willebrand factor type A domain AAA_29 PF13555.6 OWF45545.1 - 7.4e-05 22.4 4.9 14 5.6 0.1 6.2 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_25 PF13481.6 OWF45545.1 - 0.00012 21.7 5.1 6 6.4 0.0 6.3 6 0 0 6 6 6 0 AAA domain TniB PF05621.11 OWF45545.1 - 0.00022 20.7 0.0 4.9 6.5 0.0 5.7 6 0 0 6 6 6 0 Bacterial TniB protein ATPase PF06745.13 OWF45545.1 - 0.00042 19.7 0.8 1.8 7.9 0.0 4.0 4 0 0 4 4 4 2 KaiC SRPRB PF09439.10 OWF45545.1 - 0.00089 18.7 2.6 4 6.8 0.0 5.2 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit dNK PF01712.19 OWF45545.1 - 0.0018 18.2 5.0 4.4 7.1 0.0 5.5 6 0 0 6 6 5 0 Deoxynucleoside kinase Bac_DnaA PF00308.18 OWF45545.1 - 0.0034 17.3 0.1 16 5.2 0.0 5.1 5 0 0 5 5 5 0 Bacterial dnaA protein TIP49 PF06068.13 OWF45545.1 - 0.031 13.5 4.4 1.4 8.0 0.0 4.1 5 0 0 5 5 4 0 TIP49 P-loop domain cobW PF02492.19 OWF45545.1 - 0.042 13.5 5.2 0.71 9.4 0.0 4.0 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 OWF45545.1 - 0.069 12.9 0.1 2 8.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NPV_P10 PF05531.12 OWF45545.1 - 0.14 12.6 3.5 4.5 7.8 0.0 4.4 4 0 0 4 4 2 0 Nucleopolyhedrovirus P10 protein NTPase_1 PF03266.15 OWF45545.1 - 0.58 10.1 7.3 31 4.4 0.0 5.1 5 0 0 5 5 5 0 NTPase SRP54 PF00448.22 OWF45545.1 - 1.2 8.7 15.6 7.1 6.2 0.0 5.9 6 0 0 6 6 5 0 SRP54-type protein, GTPase domain LRR_8 PF13855.6 OWF45546.1 - 1.2e-58 194.7 56.4 9.2e-16 57.4 4.6 5.1 1 1 4 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 OWF45546.1 - 6.4e-27 94.0 0.0 1.4e-09 38.0 0.0 2.9 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF45546.1 - 2e-26 91.6 45.8 1.5e-06 28.4 1.2 7.3 2 1 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF45546.1 - 3.2e-11 43.0 20.2 0.0015 18.1 2.5 4.4 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 OWF45546.1 - 3.5e-11 42.0 30.2 0.5 11.1 0.3 10.2 9 1 1 10 10 10 5 Leucine Rich Repeat CSTF_C PF14304.6 OWF45546.1 - 5.7e-07 29.0 0.2 5.6 6.6 0.0 7.6 9 1 1 10 10 10 1 Transcription termination and cleavage factor C-terminal YcxB PF14317.6 OWF45546.1 - 0.0017 18.0 0.0 1.1 9.0 0.0 4.6 4 2 2 6 6 6 1 YcxB-like protein Kelch_4 PF13418.6 OWF45546.1 - 0.011 15.8 0.8 5 7.2 0.0 4.1 4 1 0 4 4 4 0 Galactose oxidase, central domain GTP_cyclohydroI PF01227.22 OWF45546.1 - 0.016 14.7 0.0 77 2.6 0.0 5.0 3 2 4 7 7 7 0 GTP cyclohydrolase I Kelch_6 PF13964.6 OWF45546.1 - 0.057 13.7 0.0 14 6.1 0.0 3.2 2 1 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 OWF45546.1 - 0.14 12.5 0.2 15 6.0 0.0 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain LRR_6 PF13516.6 OWF45546.1 - 0.15 12.2 0.2 0.15 12.2 0.2 8.0 10 0 0 10 10 10 0 Leucine Rich repeat 7tm_1 PF00001.21 OWF45547.1 - 4.6e-18 65.5 17.0 5.6e-18 65.2 17.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 OWF45547.1 - 1.3e-05 24.7 6.8 1.6e-05 24.4 6.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 OWF45547.1 - 2.8e-05 23.9 14.5 3.4e-05 23.6 13.6 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF45547.1 - 0.0018 17.6 12.7 0.11 11.8 12.7 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srbc PF10316.9 OWF45547.1 - 0.0045 16.5 4.0 0.0045 16.5 4.0 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srsx PF10320.9 OWF45547.1 - 0.0063 15.9 13.5 0.0082 15.5 13.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx WBP-1 PF11669.8 OWF45547.1 - 0.15 12.7 0.3 0.37 11.4 0.3 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 Myb_DNA-bind_4 PF13837.6 OWF45549.1 - 0.00013 22.2 0.1 0.0006 20.1 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain TraC PF07820.12 OWF45549.1 - 0.0032 17.7 0.1 0.0088 16.4 0.1 1.6 1 0 0 1 1 1 1 TraC-like protein Myb_DNA-binding PF00249.31 OWF45549.1 - 0.034 14.3 0.0 0.12 12.6 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain RPE65 PF03055.15 OWF45550.1 - 4.1e-74 250.5 2.0 4.7e-74 250.2 2.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2118 PF09891.9 OWF45551.1 - 0.00025 21.0 0.0 7 6.6 0.0 3.8 1 1 3 4 4 4 4 Uncharacterized protein conserved in archaea (DUF2118) UCR_TM PF02921.14 OWF45552.1 - 0.58 10.7 3.0 4.4 7.9 0.4 2.3 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region DDE_1 PF03184.19 OWF45553.1 - 1.4e-16 60.7 0.0 1.6e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_psq PF05225.16 OWF45553.1 - 2.1e-08 33.7 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 OWF45553.1 - 3.3e-06 26.9 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 OWF45553.1 - 0.042 14.2 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Transposase HTH_Tnp_Tc5 PF03221.16 OWF45553.1 - 0.046 13.7 0.1 0.095 12.7 0.1 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain SAM_decarbox PF01536.16 OWF45555.1 - 1.1e-120 402.9 0.6 1.3e-120 402.7 0.6 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.25 OWF45556.1 - 4.7e-59 199.9 0.1 6.6e-59 199.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF45556.1 - 2.6e-24 85.9 0.0 4.6e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF45556.1 - 0.01 15.2 0.2 0.024 14.0 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF45556.1 - 0.04 13.8 0.2 0.11 12.4 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family GMC_oxred_N PF00732.19 OWF45557.1 - 1.8e-76 257.3 0.1 2.3e-76 257.0 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF45557.1 - 6.3e-43 146.7 0.0 1.2e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF45557.1 - 1e-05 24.8 1.7 0.0043 16.2 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OWF45557.1 - 1.7e-05 24.9 1.5 3.3e-05 24.0 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OWF45557.1 - 0.0001 21.7 0.1 0.0057 15.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF45557.1 - 0.00013 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OWF45557.1 - 0.00018 20.8 0.0 0.05 12.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF45557.1 - 0.00037 19.3 0.1 0.0032 16.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OWF45557.1 - 0.0054 16.4 5.2 0.035 13.7 5.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF45557.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OWF45557.1 - 0.025 13.8 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OWF45557.1 - 0.22 11.5 1.4 0.46 10.5 0.0 2.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding HEPN_DZIP3 PF18738.1 OWF45558.1 - 1.4e-24 86.5 0.0 1.7e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN Abhydrolase_3 PF07859.13 OWF45559.1 - 2.1e-13 50.7 0.1 1.2e-12 48.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF45559.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OWF45559.1 - 0.00011 21.2 0.1 0.069 12.0 0.0 2.5 2 1 1 3 3 3 2 Carboxylesterase family FSH1 PF03959.13 OWF45559.1 - 0.00013 21.8 0.0 0.00026 20.7 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OWF45559.1 - 0.0034 18.0 0.0 0.0046 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OWF45559.1 - 0.0049 16.4 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) LIDHydrolase PF10230.9 OWF45559.1 - 0.0056 16.3 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 OWF45559.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ank_2 PF12796.7 OWF45560.1 - 6.1e-20 71.6 1.4 4.3e-07 30.4 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF45560.1 - 1.6e-14 53.6 9.2 0.00053 20.3 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OWF45560.1 - 1.9e-13 50.6 3.4 9.5e-07 29.3 0.1 5.6 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF45560.1 - 6.9e-12 44.5 8.1 6.7e-05 23.0 0.2 5.6 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF45560.1 - 7.6e-07 29.3 4.6 0.03 14.6 0.1 5.2 4 2 1 5 5 5 2 Ankyrin repeats (many copies) TIR_2 PF13676.6 OWF45561.1 - 8.5e-07 29.6 0.0 1.2e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 TIR domain DUF1685 PF07939.11 OWF45561.1 - 0.0026 17.5 11.1 8.1 6.3 0.1 6.3 1 1 6 7 7 7 1 Protein of unknown function (DUF1685) TIR PF01582.20 OWF45561.1 - 0.0053 16.6 0.0 0.0069 16.2 0.0 1.1 1 0 0 1 1 1 1 TIR domain GTPase_binding PF09027.10 OWF45561.1 - 0.017 15.1 3.9 39 4.3 0.1 4.2 1 1 3 4 4 4 0 GTPase binding Ank_2 PF12796.7 OWF45562.1 - 1.3e-26 92.9 0.7 3.4e-14 53.2 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF45562.1 - 5.4e-26 90.6 0.3 1.2e-09 38.5 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF45562.1 - 1.2e-21 76.4 0.3 7.2e-08 32.6 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF45562.1 - 1.2e-18 65.3 0.1 0.00026 21.2 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OWF45562.1 - 1.8e-17 62.9 0.1 2.9e-06 27.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat MCPVI PF02993.14 OWF45563.1 - 0.025 14.4 0.3 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Btz PF09405.10 OWF45564.1 - 1.4e-18 67.4 10.6 1.4e-18 67.4 10.6 6.0 3 2 2 5 5 5 1 CASC3/Barentsz eIF4AIII binding Chorion_1 PF01723.16 OWF45564.1 - 0.0073 16.3 3.1 0.37 10.7 0.6 2.4 1 1 1 2 2 2 2 Chorion protein Bactofilin PF04519.13 OWF45564.1 - 0.0099 16.2 0.2 0.026 14.8 0.0 1.7 2 0 0 2 2 2 1 Polymer-forming cytoskeletal ASH PF15780.5 OWF45565.1 - 2.4e-29 101.4 14.9 0.004 17.3 0.4 11.0 11 0 0 11 11 11 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OWF45565.1 - 4e-11 42.7 21.9 0.041 13.7 0.0 9.7 10 0 0 10 10 10 5 MSP (Major sperm protein) domain TMEM131_like PF12371.8 OWF45565.1 - 5e-09 36.3 5.2 0.45 10.8 0.0 6.8 6 0 0 6 6 6 2 Transmembrane protein 131-like PapD-like PF14874.6 OWF45565.1 - 3.9e-06 27.0 1.5 7 6.9 0.1 6.2 6 0 0 6 6 6 2 Flagellar-associated PapD-like Radial_spoke_3 PF06098.11 OWF45565.1 - 0.35 10.1 0.0 0.35 10.1 0.0 3.2 3 1 0 3 3 3 0 Radial spoke protein 3 WD40 PF00400.32 OWF45567.1 - 1.6e-37 126.9 26.8 8.4e-08 32.8 0.1 9.2 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF45567.1 - 2.2e-06 27.9 0.0 0.78 10.1 0.1 5.6 4 3 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF45567.1 - 7.9e-05 21.5 2.0 4.8 5.7 0.0 4.9 1 1 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF45567.1 - 0.0001 21.7 0.3 0.12 11.7 0.0 2.8 2 1 0 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 OWF45567.1 - 0.00012 22.5 8.7 5.5 7.6 0.2 6.5 8 0 0 8 8 8 2 PQQ-like domain Nucleoporin_N PF08801.11 OWF45567.1 - 0.00099 18.0 0.3 0.056 12.2 0.0 3.2 4 1 1 5 5 5 1 Nup133 N terminal like PQQ_2 PF13360.6 OWF45567.1 - 0.0087 15.7 0.0 1 8.9 0.0 2.9 2 1 1 3 3 3 1 PQQ-like domain PQQ PF01011.21 OWF45567.1 - 0.44 10.6 1.9 3.6 7.7 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat WD40 PF00400.32 OWF45568.1 - 7.2e-39 131.1 24.3 2.9e-07 31.1 0.2 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat PQQ_3 PF13570.6 OWF45568.1 - 6e-12 45.7 5.1 0.0041 17.6 0.2 6.4 6 2 1 7 7 7 2 PQQ-like domain Nup160 PF11715.8 OWF45568.1 - 1.1e-07 31.0 4.7 0.37 9.4 0.0 5.7 2 2 4 7 7 7 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OWF45568.1 - 2.4e-07 30.9 0.1 0.46 10.8 0.0 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF45568.1 - 0.025 13.6 0.3 0.16 10.9 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 OWF45568.1 - 0.029 13.9 0.1 0.86 9.1 0.1 2.6 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.11 OWF45568.1 - 0.041 12.6 0.1 1.7 7.3 0.0 3.5 3 1 1 4 4 4 0 Nup133 N terminal like PQQ PF01011.21 OWF45568.1 - 0.056 13.4 0.4 3 7.9 0.0 3.2 4 0 0 4 4 4 0 PQQ enzyme repeat Arm PF00514.23 OWF45569.1 - 3.4e-45 150.8 30.5 7.4e-08 32.2 0.2 11.6 11 0 0 11 11 11 7 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OWF45569.1 - 4.6e-10 38.7 4.7 2.2e-06 26.5 1.6 3.2 3 0 0 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.6 OWF45569.1 - 6e-07 29.8 10.1 0.00022 21.5 0.6 5.0 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 OWF45569.1 - 8.6e-07 29.1 6.3 0.0016 18.5 0.7 3.8 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OWF45569.1 - 4.3e-05 23.5 2.6 0.51 10.3 0.1 3.8 3 1 0 3 3 3 2 Domain of unknown function (DUF3361) KAP PF05804.12 OWF45569.1 - 0.00014 20.2 3.6 0.052 11.7 1.7 2.8 3 1 0 3 3 3 2 Kinesin-associated protein (KAP) Arm_2 PF04826.13 OWF45569.1 - 0.00015 21.4 5.1 0.011 15.3 0.5 4.3 3 2 2 5 5 5 1 Armadillo-like HEAT PF02985.22 OWF45569.1 - 0.00019 21.4 9.4 3.4 8.2 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Pes-10 PF07149.11 OWF45569.1 - 0.00042 19.5 1.2 0.32 10.0 0.0 2.6 2 1 1 3 3 3 2 Pes-10 HEAT_EZ PF13513.6 OWF45569.1 - 0.00044 20.7 9.4 6.4 7.4 0.2 5.6 4 1 1 5 5 5 2 HEAT-like repeat V-ATPase_H_N PF03224.14 OWF45569.1 - 0.00053 19.4 2.3 0.98 8.6 0.1 3.6 1 1 1 3 3 3 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 OWF45569.1 - 0.0065 16.5 3.9 0.016 15.2 0.3 3.4 3 2 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 OWF45569.1 - 0.064 13.7 11.0 14 6.1 0.1 5.5 5 2 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Methyltransf_25 PF13649.6 OWF45570.1 - 3.1e-14 53.4 0.0 7.2e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF45570.1 - 2.7e-12 47.2 0.0 5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF45570.1 - 5.1e-06 27.2 0.0 1.1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF45570.1 - 5.2e-06 26.3 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF45570.1 - 5.1e-05 22.7 0.0 0.00018 20.9 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF45570.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF45570.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 OWF45571.1 - 1.8e-15 57.4 0.0 5e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF45571.1 - 3e-14 53.4 0.0 1e-13 51.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF45571.1 - 1.2e-09 38.1 0.0 2.9e-09 36.9 0.0 1.5 1 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF45571.1 - 2.5e-08 33.6 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OWF45571.1 - 3e-08 34.3 0.0 8.9e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF45571.1 - 5e-05 23.2 0.0 5.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF45571.1 - 6.7e-05 22.7 0.0 7.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRODH PF18327.1 OWF45571.1 - 0.041 14.1 0.1 0.074 13.3 0.1 1.4 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain Rsm22 PF09243.10 OWF45571.1 - 0.048 12.9 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Inhibitor_I78 PF11720.8 OWF45571.1 - 0.072 13.2 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Fibrillarin PF01269.17 OWF45571.1 - 0.086 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Ephrin_rec_like PF07699.13 OWF45572.1 - 2.4e-07 30.4 97.2 5.2e-05 22.9 11.8 125.4 89 27 29 125 125 125 77 Putative ephrin-receptor like HCO3_cotransp PF00955.21 OWF45573.1 - 6e-233 774.3 10.3 7.3e-233 774.0 10.3 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 OWF45573.1 - 9.4e-58 196.1 0.0 1.5e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Reprolysin_5 PF13688.6 OWF45574.1 - 3.8e-27 95.7 2.2 3.8e-27 95.7 2.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OWF45574.1 - 4.9e-24 85.3 0.6 4.9e-24 85.3 0.6 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF45574.1 - 3.6e-15 56.6 0.2 6.7e-15 55.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 OWF45574.1 - 4.4e-12 46.2 14.5 4.4e-12 46.2 14.5 3.8 2 1 0 2 2 2 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin PF01421.19 OWF45574.1 - 1.9e-10 41.0 0.2 2.5e-06 27.5 0.1 2.7 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.23 OWF45574.1 - 3e-10 40.7 17.2 3e-10 40.7 17.2 2.9 2 0 0 2 2 2 1 Disintegrin Reprolysin_4 PF13583.6 OWF45574.1 - 4.4e-09 36.3 2.9 1.7e-08 34.3 2.9 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 OWF45574.1 - 1.3e-07 31.9 0.0 3.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide MCRS_N PF13325.6 OWF45575.1 - 9.9e-94 312.9 3.9 1.6e-93 312.2 3.9 1.4 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein FHA PF00498.26 OWF45575.1 - 7.4e-05 23.0 0.1 0.00015 22.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain DnaJ_C PF01556.18 OWF45576.1 - 1.1e-34 119.7 0.0 1.7e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OWF45576.1 - 8e-28 96.4 2.0 8e-28 96.4 2.0 1.6 2 0 0 2 2 2 1 DnaJ domain FapA PF03961.13 OWF45576.1 - 0.033 12.8 1.2 0.087 11.4 0.1 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A ATP-synt_B PF00430.18 OWF45576.1 - 0.071 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2859 PF11072.8 OWF45577.1 - 0.06 13.1 1.0 0.25 11.1 1.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) Med26 PF08711.11 OWF45578.1 - 2.2e-08 34.0 0.6 5.9e-08 32.6 0.6 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Coilin_N PF15862.5 OWF45578.1 - 1.2e-07 31.7 7.9 0.00014 21.7 0.0 4.1 2 2 3 5 5 5 1 Coilin N-terminus zf-CCCH_4 PF18044.1 OWF45578.1 - 2.9e-05 23.7 2.8 4.7e-05 23.1 2.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OWF45578.1 - 4.5e-05 23.2 0.8 7.9e-05 22.5 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF45578.1 - 0.00038 20.4 4.6 0.00067 19.6 4.6 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 OWF45578.1 - 0.027 15.0 2.2 0.052 14.0 2.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OWF45578.1 - 0.065 13.9 0.4 0.065 13.9 0.4 3.2 2 1 0 2 2 2 0 Torus domain DUF4262 PF14081.6 OWF45580.1 - 0.0032 17.7 3.5 36 4.6 0.0 5.7 3 3 3 7 7 7 1 Domain of unknown function (DUF4262) Sigma54_activat PF00158.26 OWF45580.1 - 4.5 7.0 14.6 8.8 6.0 0.3 5.1 2 1 4 7 7 7 0 Sigma-54 interaction domain ATG16 PF08614.11 OWF45581.1 - 0.00028 21.2 14.4 0.00028 21.2 14.4 12.7 2 1 8 12 12 12 3 Autophagy protein 16 (ATG16) AIP3 PF03915.13 OWF45581.1 - 0.00093 18.4 21.3 0.00093 18.4 21.3 6.7 1 1 2 5 5 5 1 Actin interacting protein 3 His_Phos_2 PF00328.22 OWF45583.1 - 1.7e-26 93.5 0.0 1.5e-16 60.8 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) IgGFc_binding PF17517.2 OWF45584.1 - 1.8e-18 66.8 0.2 3.8e-18 65.8 0.1 1.5 2 0 0 2 2 2 1 IgGFc binding protein DUF2644 PF10841.8 OWF45584.1 - 0.09 13.0 0.7 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) SAM_2 PF07647.17 OWF45585.1 - 7.7e-28 96.4 3.6 4.2e-13 49.2 0.0 4.6 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF45585.1 - 4.9e-25 87.8 2.5 2.8e-11 43.7 0.4 3.9 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF45585.1 - 0.00049 20.0 0.8 1.7 8.6 0.0 3.5 3 0 0 3 3 3 2 Sterile alpha motif (SAM)/Pointed domain FxsA PF04186.13 OWF45585.1 - 0.18 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Fib_alpha PF08702.10 OWF45585.1 - 0.32 11.2 19.3 0.095 12.9 5.8 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SesA PF17107.5 OWF45585.1 - 0.83 9.9 8.2 1.3 9.2 0.2 3.2 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DLP_helical PF18709.1 OWF45585.1 - 1.9 7.6 14.0 1.4 8.0 6.5 2.8 2 1 0 2 2 2 0 Dynamin-like helical domain MAD PF05557.13 OWF45585.1 - 2.3 6.5 36.9 3.7 5.8 1.1 3.2 1 1 1 3 3 3 0 Mitotic checkpoint protein ERM PF00769.19 OWF45585.1 - 2.6 7.8 35.7 0.3 10.9 20.2 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 OWF45585.1 - 2.7 7.4 31.0 4.2 6.7 17.8 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 OWF45585.1 - 7.4 5.3 36.6 2.1 7.1 15.5 3.2 1 1 3 4 4 4 0 Spc7 kinetochore protein SCAMP PF04144.13 OWF45587.1 - 0.091 13.1 0.3 0.091 13.1 0.3 1.8 2 0 0 2 2 2 0 SCAMP family EGF_2 PF07974.13 OWF45587.1 - 0.099 13.0 35.7 0.5 10.8 13.2 2.5 2 1 0 2 2 2 0 EGF-like domain EGF PF00008.27 OWF45587.1 - 7.5 7.0 26.8 0.99 9.8 9.7 2.9 2 1 0 2 2 2 0 EGF-like domain E1-E2_ATPase PF00122.20 OWF45588.1 - 8.2e-35 119.9 0.0 2.6e-34 118.3 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 OWF45588.1 - 1.3e-22 80.3 0.3 4.7e-22 78.4 0.3 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 OWF45588.1 - 4.2e-17 63.1 0.0 9.3e-10 39.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OWF45588.1 - 2.6e-06 27.4 0.0 7.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OWF45588.1 - 0.00011 21.8 0.0 0.00027 20.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Fringe PF02434.16 OWF45589.1 - 1.9e-16 60.3 0.8 9.2e-16 58.0 0.8 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF45589.1 - 1.2e-08 35.0 0.0 0.00011 22.0 0.1 2.6 1 1 1 2 2 2 2 Galactosyltransferase Glyco_hydro_9 PF00759.19 OWF45590.1 - 6e-138 460.7 13.9 7e-138 460.5 13.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 OWF45590.1 - 5.8e-08 33.0 0.9 4.7e-07 30.1 0.1 2.9 2 0 0 2 2 2 1 Cellulose binding domain Glyco_hydro_9 PF00759.19 OWF45591.1 - 2.6e-141 471.8 12.5 3.1e-141 471.5 12.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GD_N PF16030.5 OWF45591.1 - 0.16 12.3 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 Serine protease gd N-terminus Glyco_hydro_9 PF00759.19 OWF45592.1 - 1.4e-136 456.2 4.7 1.7e-136 455.9 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 OWF45593.1 - 2.8e-137 458.5 10.4 3.4e-137 458.2 10.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Galactosyl_T PF01762.21 OWF45594.1 - 4e-42 144.2 0.9 5.9e-42 143.7 0.9 1.2 1 0 0 1 1 1 1 Galactosyltransferase MIX PF18529.1 OWF45595.1 - 8.5e-06 25.5 9.6 43 3.7 0.0 9.6 1 1 10 12 12 12 3 Mitochondrial membrane-anchored proteins DUF2048 PF09752.9 OWF45595.1 - 0.00044 19.5 0.0 49 2.9 0.0 5.6 5 0 0 5 5 5 2 Abhydrolase domain containing 18 CDC24 PF06395.11 OWF45595.1 - 0.032 14.5 8.7 1.4e+02 2.8 0.0 7.2 4 2 2 8 8 8 0 CDC24 Calponin KH_1 PF00013.29 OWF45596.1 - 0.0065 16.3 0.0 61 3.5 0.0 4.4 3 2 2 5 5 5 0 KH domain Gag_p19 PF02228.16 OWF45596.1 - 0.042 14.3 1.4 30 5.1 0.0 3.4 1 1 1 3 3 3 0 Major core protein p19 Prolactin_RP PF15172.6 OWF45596.1 - 0.091 12.4 44.7 0.74 9.5 0.2 7.8 4 2 4 8 8 8 0 Prolactin-releasing peptide KH_1 PF00013.29 OWF45597.1 - 0.0012 18.6 0.0 2.4e+02 1.6 0.0 7.0 5 4 6 11 11 11 0 KH domain Prolactin_RP PF15172.6 OWF45597.1 - 0.0069 16.0 67.7 1.7 8.3 0.9 11.8 11 2 2 13 13 13 8 Prolactin-releasing peptide zf-FCS PF06467.14 OWF45597.1 - 3 7.8 12.2 10 6.1 0.1 6.6 7 3 1 8 8 8 0 MYM-type Zinc finger with FCS sequence motif CTD PF12815.7 OWF45598.1 - 0.00074 20.0 139.4 12 6.5 16.5 7.4 1 1 6 7 7 7 3 Spt5 C-terminal nonapeptide repeat binding Spt4 RNase_P_p30 PF01876.16 OWF45599.1 - 8.8e-07 28.6 0.0 79 2.6 0.0 8.7 2 1 13 17 17 17 0 RNase P subunit p30 Phage_tail_T PF06223.12 OWF45599.1 - 4.7e-06 27.0 0.0 4.1 8.0 0.0 6.3 1 1 8 9 9 9 1 Minor tail protein T UMP1 PF05348.11 OWF45599.1 - 0.019 15.2 0.1 71 3.7 0.0 6.0 5 2 2 8 8 8 0 Proteasome maturation factor UMP1 Glt_symporter PF03616.14 OWF45599.1 - 0.33 9.6 11.6 74 1.9 0.0 6.7 1 1 7 11 11 11 0 Sodium/glutamate symporter Plasmodium_HRP PF05403.11 OWF45600.1 - 6.4e-09 35.9 83.0 0.0003 20.7 33.0 3.1 1 1 2 3 3 3 3 Plasmodium histidine-rich protein (HRPII/III) Tcp10_C PF07202.13 OWF45600.1 - 0.0071 16.3 10.9 0.15 12.0 0.9 3.2 1 1 2 3 3 3 3 T-complex protein 10 C-terminus PP2C PF00481.21 OWF45601.1 - 0.00019 21.2 3.9 1.1 8.9 0.2 4.2 1 1 2 3 3 3 3 Protein phosphatase 2C zf-C2H2 PF00096.26 OWF45602.1 - 2.8e-19 68.4 56.9 4.6e-06 26.8 2.7 7.8 7 1 1 8 8 8 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF45602.1 - 2.2e-15 56.3 57.2 1.2e-07 31.9 1.9 7.7 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF45602.1 - 2.3e-10 40.4 58.4 0.00075 20.1 2.1 8.1 7 2 1 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 OWF45602.1 - 0.0074 16.7 1.3 0.0074 16.7 1.3 6.2 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF45602.1 - 0.15 12.3 39.8 0.13 12.6 2.7 4.8 2 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 OWF45602.1 - 0.49 11.2 20.9 1.9 9.3 0.1 3.7 2 1 0 3 3 3 0 zinc-ribbon family zf-C2H2_11 PF16622.5 OWF45602.1 - 4.7 7.0 29.2 0.19 11.5 0.6 5.4 5 0 0 5 5 5 0 zinc-finger C2H2-type PMP22_Claudin PF00822.20 OWF45603.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family WSC PF01822.19 OWF45603.1 - 0.12 12.6 1.2 0.52 10.5 1.2 2.1 1 0 0 1 1 1 0 WSC domain Trypsin PF00089.26 OWF45604.1 - 3.5e-34 118.5 1.8 4.4e-34 118.2 1.8 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 OWF45604.1 - 0.00055 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 OWF45604.1 - 0.0012 19.8 0.2 0.0018 19.2 0.2 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF45605.1 - 5.8e-51 173.4 2.7 6.6e-51 173.2 2.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF45605.1 - 3.4e-05 24.8 0.5 7e-05 23.8 0.5 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF45605.1 - 0.0029 18.0 0.1 0.007 16.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Bac_RepA_C PF18008.1 OWF45606.1 - 0.022 15.1 5.5 4.5 7.7 0.3 4.6 1 1 3 5 5 5 0 Replication initiator protein A C-terminal domain FAD_syn PF06574.12 OWF45606.1 - 0.029 14.2 0.2 9.5 6.1 0.0 2.4 1 1 1 2 2 2 0 FAD synthetase DUF4164 PF13747.6 OWF45606.1 - 0.13 12.6 0.0 2.3 8.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Exonuc_VII_L PF02601.15 OWF45606.1 - 0.35 10.4 4.4 0.45 10.0 4.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM183 PF14886.6 OWF45606.1 - 1.4 9.7 25.3 1.8e+04 -5.8 25.3 3.3 1 1 0 1 1 1 0 FAM183A and FAM183B related Trypsin PF00089.26 OWF45607.1 - 4.7e-16 59.3 0.2 5.5e-16 59.1 0.2 1.0 1 0 0 1 1 1 1 Trypsin Ras PF00071.22 OWF45608.1 - 2e-46 157.5 0.1 1.6e-33 115.6 0.0 2.7 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OWF45608.1 - 9.5e-16 58.1 0.0 1.3e-07 31.8 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase VWA_2 PF13519.6 OWF45608.1 - 3e-07 31.1 0.6 0.0036 17.9 0.0 3.8 3 1 1 4 4 4 2 von Willebrand factor type A domain zf-Sec23_Sec24 PF04810.15 OWF45608.1 - 1.1e-06 28.5 2.3 2.4e-06 27.5 2.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Arf PF00025.21 OWF45608.1 - 2.9e-06 26.8 0.2 0.0014 18.1 0.0 2.7 2 1 1 3 3 3 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF45608.1 - 5.9e-05 22.7 0.1 0.0004 20.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain VWA PF00092.28 OWF45608.1 - 0.00082 19.7 0.5 2.1 8.6 0.0 3.3 3 1 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF45608.1 - 0.0039 16.6 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein DUF1631 PF07793.11 OWF45608.1 - 0.0049 15.4 1.2 0.0049 15.4 1.2 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1631) Sec23_BS PF08033.12 OWF45608.1 - 0.028 15.1 0.0 0.07 13.9 0.0 1.7 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain FeoB_N PF02421.18 OWF45608.1 - 0.065 12.8 0.0 0.065 12.8 0.0 2.8 4 0 0 4 4 4 0 Ferrous iron transport protein B Cas_csx3 PF09620.10 OWF45608.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) WES_acyltransf PF03007.16 OWF45608.1 - 0.15 11.8 0.5 0.3 10.8 0.5 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF4749 PF15936.5 OWF45610.1 - 1.3 10.1 5.7 0.69 11.1 2.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4749) DUF2723 PF11028.8 OWF45611.1 - 3e-34 118.4 9.1 3e-34 118.4 9.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) DUF3931 PF13082.6 OWF45611.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) Auto_anti-p27 PF06677.12 OWF45613.1 - 1.3e-13 50.8 3.3 2.3e-13 50.1 3.3 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Spt4 PF06093.13 OWF45613.1 - 0.18 12.0 1.5 0.58 10.3 1.5 2.0 1 1 0 1 1 1 0 Spt4/RpoE2 zinc finger AMP-binding PF00501.28 OWF45614.1 - 2.6e-69 233.9 0.0 3.7e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OWF45614.1 - 1.6e-47 161.8 0.0 2.4e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Formyl_trans_N PF00551.19 OWF45614.1 - 4.3e-18 65.7 0.0 1.7e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Formyl transferase PP-binding PF00550.25 OWF45614.1 - 2.4e-08 34.2 0.1 5.8e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OWF45614.1 - 1.6e-06 28.9 0.1 3.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 OWF45614.1 - 0.00027 20.0 0.0 0.0005 19.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OWF45614.1 - 0.013 14.9 0.0 0.051 13.0 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF45614.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 OWF45615.1 - 3.1e-51 174.6 0.0 4.4e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S41_N PF11918.8 OWF45615.1 - 0.071 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Methyltransf_25 PF13649.6 OWF45616.1 - 0.00023 21.8 0.0 0.0013 19.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF45616.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF45616.1 - 0.062 14.0 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OWF45616.1 - 0.19 11.3 0.0 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Branch PF02485.21 OWF45617.1 - 1.2e-43 149.5 0.0 1.6e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme INCENP_N PF12178.8 OWF45617.1 - 0.058 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal TFCD_C PF12612.8 OWF45618.1 - 1.4e-66 224.0 0.2 2.1e-65 220.1 0.0 2.9 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 OWF45618.1 - 7.3e-10 38.3 0.8 0.13 12.6 0.0 7.7 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 OWF45618.1 - 2e-08 34.6 1.8 0.091 13.3 0.0 5.6 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 OWF45618.1 - 3.9e-06 27.2 3.0 0.37 11.2 0.0 4.9 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 OWF45618.1 - 0.00027 21.0 0.1 0.65 10.0 0.0 4.7 7 0 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OWF45618.1 - 0.0023 18.5 0.6 24 5.6 0.0 5.0 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cas9_b_hairpin PF17893.1 OWF45618.1 - 0.14 12.0 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain Fam20C PF06702.12 OWF45619.1 - 3.4e-91 304.9 0.8 5.7e-91 304.2 0.2 1.7 2 0 0 2 2 2 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 OWF45619.1 - 0.00046 19.2 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 FAM198 protein DEAD PF00270.29 OWF45620.1 - 3.6e-47 160.4 0.0 7e-47 159.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF45620.1 - 8.4e-30 103.4 0.0 1.7e-27 96.0 0.0 3.6 3 1 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 OWF45620.1 - 3e-26 91.6 0.0 7.4e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 OWF45620.1 - 3e-09 37.1 0.4 1.9e-08 34.5 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OWF45620.1 - 0.00072 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 OWF45620.1 - 0.0016 17.7 0.0 0.0016 17.7 0.0 1.9 2 0 0 2 2 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 OWF45620.1 - 0.0057 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 OWF45620.1 - 0.027 13.8 0.0 0.027 13.8 0.0 2.4 2 0 0 2 2 1 0 U3-containing 90S pre-ribosomal complex subunit Lyase_N PF09092.11 OWF45620.1 - 0.057 13.3 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Lyase, N terminal SecA_DEAD PF07517.14 OWF45620.1 - 0.093 12.0 2.5 0.086 12.1 0.3 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain BSP_II PF05432.11 OWF45620.1 - 0.11 12.2 15.6 0.23 11.1 15.6 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) AAA_11 PF13086.6 OWF45620.1 - 0.85 9.4 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4364 PF14277.6 OWF45620.1 - 1 9.1 4.9 29 4.4 0.0 3.6 3 1 1 4 4 3 0 Domain of unknown function (DUF4364) IRF PF00605.17 OWF45621.1 - 5e-33 113.5 1.2 9e-33 112.7 1.2 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Ets PF00178.22 OWF45621.1 - 0.12 12.9 0.5 0.25 11.8 0.5 1.6 1 0 0 1 1 1 0 Ets-domain NOA36 PF06524.12 OWF45621.1 - 0.23 10.7 3.2 0.37 10.1 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OWF45621.1 - 2.1 8.0 4.4 0.86 9.3 1.3 1.9 2 0 0 2 2 2 0 FAM176 family IRF PF00605.17 OWF45622.1 - 6.4e-34 116.4 1.0 1.1e-33 115.7 1.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor DUF3094 PF11293.8 OWF45622.1 - 0.048 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) MAF_flag10 PF01973.18 OWF45622.1 - 0.2 11.4 0.1 8.2 6.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF115 DWNN PF08783.11 OWF45623.1 - 2.8e-25 88.4 0.6 2.8e-25 88.4 0.6 2.5 2 0 0 2 2 1 1 DWNN domain zf-CCHC_2 PF13696.6 OWF45623.1 - 7.3e-05 22.5 5.6 0.00017 21.4 5.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OWF45623.1 - 0.00018 21.4 3.7 0.00035 20.5 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OWF45623.1 - 0.00051 20.0 0.1 0.0015 18.4 0.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 OWF45623.1 - 0.00074 19.3 14.6 0.0017 18.2 14.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF45623.1 - 0.0015 18.3 12.4 0.0035 17.2 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 OWF45623.1 - 0.0022 18.1 0.5 0.0089 16.2 0.0 2.4 2 0 0 2 2 1 1 U-box domain zf-RING_5 PF14634.6 OWF45623.1 - 0.021 14.8 12.6 0.047 13.7 12.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF45623.1 - 0.022 14.9 15.5 0.048 13.8 15.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF45623.1 - 0.084 13.2 14.2 0.17 12.3 14.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 OWF45623.1 - 0.53 10.2 7.6 1 9.3 7.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 OWF45623.1 - 0.94 9.4 14.6 2 8.4 14.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF45623.1 - 4.9 7.3 11.4 12 6.0 11.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger AAA_12 PF13087.6 OWF45624.1 - 5.7e-38 130.5 0.0 1.8e-37 128.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OWF45624.1 - 1.1e-19 71.3 14.8 6.9e-12 45.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 OWF45624.1 - 1.4e-07 31.5 0.0 6.7e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF45624.1 - 5.7e-05 23.5 0.0 0.00038 20.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 OWF45624.1 - 0.00016 21.7 2.3 0.00025 21.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OWF45624.1 - 0.0012 18.4 0.0 0.047 13.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein TPR_19 PF14559.6 OWF45624.1 - 0.0042 17.6 0.1 0.016 15.7 0.1 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat Helicase_RecD PF05127.14 OWF45624.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Helicase PAM2 PF07145.15 OWF45624.1 - 0.012 15.3 0.2 0.012 15.3 0.2 2.0 2 0 0 2 2 1 0 Ataxin-2 C-terminal region AAA_22 PF13401.6 OWF45624.1 - 0.014 15.6 0.0 0.073 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 OWF45624.1 - 0.027 14.3 0.2 0.094 12.6 0.2 1.9 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain SRP54 PF00448.22 OWF45624.1 - 0.028 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OWF45624.1 - 0.033 14.6 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain zf-CCCH PF00642.24 OWF45624.1 - 0.038 13.9 0.2 0.079 12.9 0.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_7 PF12775.7 OWF45624.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_14 PF13428.6 OWF45624.1 - 0.049 14.5 0.0 7.3 7.7 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Bac_DnaA PF00308.18 OWF45624.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein zf-C2H2_jaz PF12171.8 OWF45624.1 - 0.077 13.3 3.4 0.19 12.1 3.4 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Mg_chelatase PF01078.21 OWF45624.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF45624.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4187 PF13821.6 OWF45624.1 - 0.12 12.2 0.4 0.4 10.5 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) AAA PF00004.29 OWF45624.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ANAPC3 PF12895.7 OWF45624.1 - 0.18 12.1 0.3 0.62 10.3 0.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Laps PF10169.9 OWF45624.1 - 3 8.4 8.4 0.19 12.3 2.2 2.2 2 0 0 2 2 1 0 Learning-associated protein Amino_oxidase PF01593.24 OWF45625.1 - 1.2e-75 255.5 0.0 1.4e-75 255.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF45625.1 - 3.6e-13 49.5 0.3 7e-13 48.6 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF45625.1 - 1.5e-05 24.3 0.2 2.3e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OWF45625.1 - 4.3e-05 23.2 0.3 8.3e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF45625.1 - 0.00066 19.0 0.2 0.0077 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF45625.1 - 0.0012 18.2 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OWF45625.1 - 0.0021 17.4 0.2 0.0034 16.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OWF45625.1 - 0.012 16.2 0.7 0.042 14.4 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF45625.1 - 0.022 14.0 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OWF45625.1 - 0.035 12.8 0.1 0.063 12.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OWF45625.1 - 0.13 11.4 0.2 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OWF45625.1 - 0.17 11.2 0.3 0.29 10.4 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OWF45625.1 - 0.21 10.9 0.1 0.36 10.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAM199X PF15814.5 OWF45626.1 - 0.34 9.9 8.8 0.5 9.4 8.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X CBM_14 PF01607.24 OWF45628.1 - 5.2e-25 87.4 22.2 1.5e-14 53.9 7.4 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain DUF1196 PF06709.11 OWF45628.1 - 0.0094 16.1 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1196) HECT PF00632.25 OWF45629.1 - 6.9e-98 327.9 0.0 9.5e-98 327.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OWF45629.1 - 6.6e-28 96.5 9.7 3e-09 36.8 0.2 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 OWF45629.1 - 6.1e-16 58.6 0.0 1.6e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain AAA PF00004.29 OWF45630.1 - 4.6e-06 27.1 0.1 8.1e-05 23.1 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF45630.1 - 1.4e-05 25.4 1.0 0.0015 18.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain F-box-like PF12937.7 OWF45630.1 - 8.1 6.4 7.8 0.48 10.4 0.1 2.5 3 0 0 3 3 3 0 F-box-like Sec23_trunk PF04811.15 OWF45631.1 - 9.1e-80 267.7 0.0 1.4e-79 267.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OWF45631.1 - 2.1e-27 95.0 0.1 3.6e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OWF45631.1 - 1.6e-16 60.1 0.8 3.2e-16 59.1 0.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OWF45631.1 - 3.5e-16 59.7 0.0 7.1e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 OWF45631.1 - 3.3e-09 36.5 0.1 2.1e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Gelsolin repeat PMP22_Claudin PF00822.20 OWF45632.1 - 1.4e-05 25.0 2.5 5.3e-05 23.2 2.5 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF45632.1 - 9.3e-05 22.3 4.2 0.008 16.0 1.0 2.3 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF45632.1 - 0.0045 16.9 4.3 0.0072 16.3 4.3 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like L_HMGIC_fpl PF10242.9 OWF45632.1 - 0.0062 16.8 3.2 0.018 15.3 3.2 1.9 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 OWF45632.1 - 0.019 14.5 1.3 1.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Clc-like Claudin_2 PF13903.6 OWF45633.1 - 3e-05 23.9 5.5 7.1e-05 22.6 5.5 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 OWF45633.1 - 0.0067 16.6 1.7 0.0067 16.6 1.7 1.9 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Prenyltrans PF00432.21 OWF45633.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DuoxA PF10204.9 OWF45633.1 - 0.034 13.2 1.1 0.072 12.1 1.1 1.5 1 0 0 1 1 1 0 Dual oxidase maturation factor Claudin_3 PF06653.11 OWF45633.1 - 0.11 12.4 10.8 0.23 11.4 10.8 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 OWF45634.1 - 8e-08 32.3 7.8 1.1e-07 31.9 7.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF45634.1 - 2.4e-06 27.4 7.2 9.4e-06 25.5 7.2 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 OWF45634.1 - 0.00031 21.0 7.1 0.00045 20.5 2.1 2.1 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein DuoxA PF10204.9 OWF45634.1 - 0.00046 19.3 1.2 0.00046 19.3 1.2 1.8 2 1 0 2 2 2 1 Dual oxidase maturation factor Claudin_3 PF06653.11 OWF45634.1 - 0.024 14.6 11.7 0.041 13.8 11.7 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Clc-like PF07062.12 OWF45634.1 - 0.026 14.0 9.4 0.8 9.1 3.4 2.2 1 1 0 2 2 2 0 Clc-like Glyco_transf_10 PF00852.19 OWF45635.1 - 1.8e-34 119.0 0.5 3.5e-34 118.0 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF45635.1 - 6.4e-12 45.9 0.1 1.3e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal HHH_5 PF14520.6 OWF45636.1 - 0.044 14.4 0.1 0.088 13.4 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Apolipoprotein PF01442.18 OWF45637.1 - 1.3e-06 28.4 18.7 2.5e-06 27.5 18.7 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 OWF45637.1 - 0.0054 17.2 2.0 0.069 13.7 0.0 3.2 2 2 0 2 2 2 1 YtxH-like protein FliT PF05400.13 OWF45637.1 - 0.018 15.8 18.5 1 10.2 7.0 3.6 2 1 1 3 3 3 0 Flagellar protein FliT NPR1_interact PF15699.5 OWF45637.1 - 0.019 15.6 1.1 0.019 15.6 1.1 3.0 2 1 0 2 2 2 0 NPR1 interacting MHCassoc_trimer PF08831.10 OWF45637.1 - 0.033 14.2 7.5 7.1 6.7 0.3 3.9 1 1 2 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain DUF445 PF04286.12 OWF45637.1 - 0.039 13.8 3.5 0.057 13.2 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Bacillus_HBL PF05791.11 OWF45637.1 - 0.31 10.9 4.9 1.6 8.5 4.9 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF883 PF05957.13 OWF45637.1 - 1.2 9.8 9.5 14 6.4 7.9 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3810 PF12725.7 OWF45637.1 - 1.5 8.1 6.1 1.1 8.5 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) kleA_kleC PF17383.2 OWF45637.1 - 1.6 9.1 9.7 1.2e+02 3.1 2.0 3.6 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A IZUMO PF15005.6 OWF45637.1 - 3.3 8.2 14.6 10 6.6 9.3 2.7 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated AAA_22 PF13401.6 OWF45637.1 - 3.7 7.8 8.5 19 5.5 8.2 2.1 1 1 0 1 1 1 0 AAA domain RcbX PF02341.15 OWF45637.1 - 5.3 7.3 12.2 15 5.9 9.4 2.5 1 1 1 2 2 2 0 RbcX protein Exonuc_VII_L PF02601.15 OWF45637.1 - 6.3 6.3 10.3 9.7 5.6 10.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pro-MCH PF05824.12 OWF45639.1 - 0.93 9.5 9.9 1.3e+02 2.6 0.0 7.1 8 1 1 9 9 9 0 Pro-melanin-concentrating hormone (Pro-MCH) UQ_con PF00179.26 OWF45640.1 - 1.4e-51 173.8 0.0 1.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF45640.1 - 0.026 14.8 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OWF45640.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain C2 PF00168.30 OWF45641.1 - 1.1e-38 131.6 0.2 1.9e-17 63.4 0.0 4.6 3 1 0 3 3 3 2 C2 domain Membr_traf_MHD PF10540.9 OWF45641.1 - 8.2e-12 45.5 6.3 6.4e-06 26.4 0.2 2.7 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain RNA_pol_Rpb1_1 PF04997.12 OWF45643.1 - 4.5e-89 298.9 2.8 6.8e-89 298.3 2.8 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OWF45643.1 - 1.6e-88 296.6 1.7 2.7e-88 295.9 1.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OWF45643.1 - 3.3e-73 245.4 0.1 7e-73 244.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OWF45643.1 - 3.8e-40 137.4 0.0 1.4e-39 135.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OWF45643.1 - 1.2e-30 105.6 0.0 4e-30 103.9 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Chorismate_synt PF01264.21 OWF45643.1 - 0.08 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Chorismate synthase zf-tcix PF14952.6 OWF45643.1 - 0.14 11.8 2.4 0.4 10.3 2.4 1.8 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zinc-ribbons_6 PF07191.12 OWF45643.1 - 4.8 7.2 6.4 3.5 7.7 2.4 2.6 2 0 0 2 2 2 0 zinc-ribbons SF1-HH PF16275.5 OWF45644.1 - 3.8e-41 140.0 2.6 3.8e-41 140.0 2.6 2.1 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 OWF45644.1 - 9.9e-09 34.9 1.4 3.4e-08 33.2 1.4 2.0 1 1 0 1 1 1 1 KH domain zf-CCHC PF00098.23 OWF45644.1 - 0.00065 19.7 0.6 0.0011 18.9 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OWF45644.1 - 0.06 13.1 2.5 1.8 8.3 0.5 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Sulfotransfer_1 PF00685.27 OWF45645.1 - 1.6e-42 145.9 0.4 4.7e-41 141.0 0.4 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF45645.1 - 2.4e-09 37.9 0.0 2.7e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family MOZ_SAS PF01853.18 OWF45646.1 - 3.2e-85 284.3 0.1 4.7e-85 283.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OWF45646.1 - 2.2e-24 84.8 5.8 2.2e-24 84.8 5.8 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 OWF45646.1 - 3.7e-20 71.6 1.2 5.8e-20 70.9 0.3 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OWF45646.1 - 0.0082 16.6 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SAWADEE PF16719.5 OWF45646.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 SAWADEE domain DUF2314 PF10077.9 OWF45646.1 - 0.052 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Evf PF18270.1 OWF45646.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Virulence factor Evf Chromo PF00385.24 OWF45646.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.6 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Ank_2 PF12796.7 OWF45647.1 - 1e-08 35.6 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF45647.1 - 1.6e-08 34.6 0.1 1.1e-06 28.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OWF45647.1 - 5e-08 32.6 0.0 1.9e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OWF45647.1 - 6.3e-08 32.7 0.1 1.6e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF45647.1 - 7.2e-07 29.6 0.2 4.4e-06 27.1 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Glyco_transf_10 PF00852.19 OWF45648.1 - 2.2e-47 161.1 3.2 4e-47 160.2 3.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF45648.1 - 2.8e-17 63.2 1.6 5.3e-17 62.3 0.0 2.2 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal Hat1_N PF10394.9 OWF45648.1 - 0.036 14.3 0.3 0.17 12.1 0.1 2.0 1 1 1 2 2 2 0 Histone acetyl transferase HAT1 N-terminus 7TM_GPCR_Srw PF10324.9 OWF45649.1 - 8.6e-20 71.2 23.3 1.1e-17 64.4 23.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF45649.1 - 1e-18 67.6 11.8 1.4e-18 67.2 11.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF45649.1 - 2.4e-05 23.9 18.9 9e-05 22.0 18.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF45649.1 - 8e-05 22.4 12.5 8e-05 22.4 12.5 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MIB_HERC2 PF06701.13 OWF45650.1 - 4.9e-15 55.5 1.6 4.9e-15 55.5 1.6 2.0 3 0 0 3 3 1 1 Mib_herc2 Fez1 PF06818.15 OWF45650.1 - 0.00024 21.6 6.4 0.00034 21.1 6.4 1.2 1 0 0 1 1 1 1 Fez1 ADIP PF11559.8 OWF45650.1 - 0.00078 19.6 10.2 0.0031 17.6 8.3 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 OWF45650.1 - 0.003 16.3 2.7 0.0037 16.0 2.7 1.0 1 0 0 1 1 1 1 AAA domain DUF4972 PF16342.5 OWF45650.1 - 0.0081 15.9 0.4 0.02 14.6 0.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4972) MbeD_MobD PF04899.12 OWF45650.1 - 0.022 14.9 13.7 0.089 12.9 4.8 2.5 2 1 0 2 2 2 0 MbeD/MobD like FlaC_arch PF05377.11 OWF45650.1 - 0.025 15.0 4.8 0.26 11.7 0.4 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OWF45650.1 - 0.028 14.5 7.7 0.18 11.9 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 OWF45650.1 - 0.034 14.5 5.3 4.6 7.7 0.2 3.0 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 OWF45650.1 - 0.043 12.7 8.7 0.073 11.9 8.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein H-kinase_dim PF02895.14 OWF45650.1 - 0.053 13.9 9.4 0.93 9.9 2.4 2.8 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Meis_PKNOX_N PF16493.5 OWF45650.1 - 0.059 13.7 2.3 4.7 7.6 0.7 2.3 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 KASH_CCD PF14662.6 OWF45650.1 - 0.068 13.0 12.0 0.023 14.6 6.9 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Taxilin PF09728.9 OWF45650.1 - 0.073 12.2 9.5 0.12 11.5 9.5 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein BLOC1_2 PF10046.9 OWF45650.1 - 0.087 13.1 10.7 0.34 11.2 1.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TACC_C PF05010.14 OWF45650.1 - 0.089 12.6 7.1 0.18 11.6 3.1 1.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-F_leu_zip PF10473.9 OWF45650.1 - 0.091 12.8 12.3 0.63 10.1 5.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1028 PF06267.12 OWF45650.1 - 0.11 12.3 2.7 0.2 11.4 2.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF1028) FAM76 PF16046.5 OWF45650.1 - 0.14 11.5 2.6 0.18 11.1 2.6 1.1 1 0 0 1 1 1 0 FAM76 protein DUF812 PF05667.11 OWF45650.1 - 0.14 11.0 8.0 0.07 12.0 5.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DivIVA PF05103.13 OWF45650.1 - 0.15 12.1 10.8 2.1 8.5 0.8 2.2 1 1 1 2 2 2 0 DivIVA protein TSC22 PF01166.18 OWF45650.1 - 0.17 12.2 6.5 0.12 12.7 1.2 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family EzrA PF06160.12 OWF45650.1 - 0.19 9.9 8.6 0.26 9.4 8.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AIP3 PF03915.13 OWF45650.1 - 0.2 10.7 7.0 0.28 10.2 7.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 ATG16 PF08614.11 OWF45650.1 - 0.29 11.3 14.8 1.2 9.3 7.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.13 OWF45650.1 - 0.3 11.8 4.2 5.1 7.9 0.3 2.3 1 1 1 2 2 2 0 Occludin homology domain HAUS-augmin3 PF14932.6 OWF45650.1 - 0.32 10.5 12.8 0.47 10.0 12.1 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 OWF45650.1 - 0.42 9.9 6.4 1.6 8.0 6.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Gastrin PF00918.17 OWF45650.1 - 0.45 11.5 4.0 0.36 11.8 1.8 1.8 1 1 1 2 2 2 0 Gastrin/cholecystokinin family DUF3450 PF11932.8 OWF45650.1 - 0.45 9.8 15.8 0.65 9.3 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 OWF45650.1 - 0.49 10.7 10.3 5.6 7.3 10.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ORF6C PF10552.9 OWF45650.1 - 0.54 10.4 3.6 0.39 10.8 0.8 2.0 1 1 1 2 2 2 0 ORF6C domain HAP1_N PF04849.13 OWF45650.1 - 0.58 9.3 15.4 2.2 7.4 15.4 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Lebercilin PF15619.6 OWF45650.1 - 0.73 9.5 9.8 2 8.0 0.5 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.10 OWF45650.1 - 0.86 9.9 8.7 4.2 7.7 3.4 2.4 1 1 1 2 2 2 0 Tup N-terminal Fib_alpha PF08702.10 OWF45650.1 - 1.2 9.3 13.4 1.1 9.4 0.5 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YabA PF06156.13 OWF45650.1 - 1.5 9.5 10.7 3.7 8.3 4.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 OWF45650.1 - 1.9 8.7 5.2 15 5.7 0.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor Perilipin PF03036.16 OWF45650.1 - 1.9 7.5 15.1 2.6 7.0 15.1 1.1 1 0 0 1 1 1 0 Perilipin family WEMBL PF05701.11 OWF45650.1 - 2.1 6.9 7.6 2.6 6.7 6.5 1.5 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Telomere_reg-2 PF10193.9 OWF45650.1 - 2.3 8.7 6.9 1.4e+02 3.0 7.0 2.8 1 1 0 1 1 1 0 Telomere length regulation protein SKA1 PF07160.12 OWF45650.1 - 2.8 7.7 11.5 4.7 7.0 6.7 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Laminin_II PF06009.12 OWF45650.1 - 3.1 7.8 10.2 3.3 7.7 3.6 2.3 1 1 1 2 2 2 0 Laminin Domain II USP8_interact PF08941.10 OWF45650.1 - 3.2 7.5 9.0 1.4 8.7 1.2 2.2 1 1 1 2 2 2 0 USP8 interacting DivIC PF04977.15 OWF45650.1 - 3.6 7.4 8.8 7.7 6.4 2.7 2.6 1 1 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 OWF45650.1 - 4.7 7.7 16.2 7.2 7.1 0.8 3.0 1 1 1 2 2 2 0 Cell division protein ZapB NPV_P10 PF05531.12 OWF45650.1 - 4.7 7.7 16.9 72 4.0 1.0 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 OWF45650.1 - 6 7.6 17.7 3.4 8.4 1.1 3.3 2 1 1 3 3 3 0 SlyX Tetraspanin PF00335.20 OWF45651.1 - 0.53 10.0 3.9 0.81 9.4 3.9 1.2 1 0 0 1 1 1 0 Tetraspanin family PMP22_Claudin PF00822.20 OWF45651.1 - 1.7 8.5 7.1 4.5 7.1 6.9 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family MgtE PF01769.16 OWF45652.1 - 0.046 14.1 1.1 0.069 13.5 1.1 1.2 1 0 0 1 1 1 0 Divalent cation transporter PIRT PF15099.6 OWF45653.1 - 3.2e-06 26.8 0.2 5.7e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Phage_holin_3_6 PF07332.11 OWF45653.1 - 0.00031 20.8 0.1 0.00046 20.2 0.1 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF3341 PF11821.8 OWF45653.1 - 0.0038 16.9 0.1 0.0049 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) Nucleoside_tran PF01733.18 OWF45653.1 - 0.006 16.0 0.2 0.0071 15.8 0.2 1.1 1 0 0 1 1 1 1 Nucleoside transporter DUF2207 PF09972.9 OWF45653.1 - 0.0062 15.4 0.2 0.0094 14.8 0.2 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM171 PF15471.6 OWF45653.1 - 0.023 13.7 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 SUR7 PF06687.12 OWF45653.1 - 0.032 13.9 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 SUR7/PalI family FtsX PF02687.21 OWF45653.1 - 0.051 14.0 3.1 0.084 13.3 3.1 1.3 1 0 0 1 1 1 0 FtsX-like permease family LapA_dom PF06305.11 OWF45653.1 - 0.051 13.4 1.6 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RseC_MucC PF04246.12 OWF45653.1 - 0.07 13.1 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC OSTbeta PF15048.6 OWF45653.1 - 0.073 13.2 0.2 0.073 13.2 0.2 1.6 2 1 0 2 2 1 0 Organic solute transporter subunit beta protein CrgA PF06781.12 OWF45653.1 - 0.076 13.1 1.0 0.1 12.7 0.1 1.7 2 0 0 2 2 2 0 Cell division protein CrgA TMEM174 PF15029.6 OWF45653.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 Tetraspanin PF00335.20 OWF45653.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3040 PF11239.8 OWF45653.1 - 0.32 11.3 5.7 4.2 7.7 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF973 PF06157.11 OWF45653.1 - 0.42 9.6 8.7 0.41 9.7 8.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) PufQ PF05398.11 OWF45653.1 - 0.47 10.6 4.5 0.36 11.0 1.3 2.4 1 1 1 2 2 2 0 PufQ cytochrome subunit Saf_2TM PF18303.1 OWF45653.1 - 0.53 9.9 5.0 1.6 8.3 5.0 1.9 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain DUF1218 PF06749.12 OWF45653.1 - 0.75 10.4 3.0 19 5.9 1.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1218) HLH PF00010.26 OWF45654.1 - 8e-19 67.4 0.2 1.5e-18 66.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MMADHC PF10229.9 OWF45654.1 - 0.02 14.6 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein Protamine_3 PF08188.11 OWF45654.1 - 0.068 13.4 2.7 0.11 12.6 2.7 1.3 1 0 0 1 1 1 0 Spermatozal protamine family Glyco_hydro_38N PF01074.22 OWF45655.1 - 2.8e-94 315.7 1.3 4e-94 315.2 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF45655.1 - 3.2e-44 151.6 0.0 7.1e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF45655.1 - 3.5e-23 81.6 0.0 1.2e-22 79.9 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OWF45655.1 - 1.1e-08 35.1 0.0 3.6e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain CHU_C PF13585.6 OWF45655.1 - 0.068 13.2 0.4 2.5 8.2 0.0 3.0 2 1 1 3 3 3 0 C-terminal domain of CHU protein family Glyco_hydro_38N PF01074.22 OWF45656.1 - 1.5e-92 310.1 3.9 2.2e-92 309.5 3.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF45656.1 - 4.7e-43 147.7 0.4 8.1e-43 147.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF45656.1 - 6.8e-22 77.4 0.1 1.7e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OWF45656.1 - 6.5e-11 42.2 0.1 1.9e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF4304 PF14137.6 OWF45656.1 - 0.14 12.3 0.9 0.38 10.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) DUF5053 PF16476.5 OWF45656.1 - 0.15 11.8 0.4 6 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) CHGN PF05679.16 OWF45657.1 - 3.9e-85 286.6 0.3 5e-85 286.3 0.3 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 OWF45657.1 - 1.5e-10 40.6 0.6 8.5e-10 38.2 1.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Spc29 PF17082.5 OWF45657.1 - 0.01 15.7 0.8 0.017 15.0 0.8 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 Glyco_tranf_2_2 PF10111.9 OWF45657.1 - 0.016 14.7 0.2 0.15 11.5 0.2 2.1 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Macoilin PF09726.9 OWF45657.1 - 0.13 10.8 2.4 0.18 10.3 2.4 1.1 1 0 0 1 1 1 0 Macoilin family FlaC_arch PF05377.11 OWF45657.1 - 0.2 12.1 1.5 0.41 11.1 1.5 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) KLRAQ PF10205.9 OWF45657.1 - 0.23 11.7 4.9 0.49 10.7 4.9 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein GrpE PF01025.19 OWF45657.1 - 0.46 10.1 6.1 0.32 10.7 1.5 2.5 3 0 0 3 3 3 0 GrpE Acetyltransf_19 PF18015.1 OWF45657.1 - 0.53 10.5 2.7 0.41 10.9 0.4 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RPN7 PF10602.9 OWF45657.1 - 0.55 9.9 3.5 0.88 9.3 2.7 1.7 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DivIC PF04977.15 OWF45657.1 - 0.68 9.7 6.9 0.23 11.2 3.3 2.0 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 OWF45657.1 - 6.3 7.0 7.7 9 6.5 4.1 2.6 2 1 0 2 2 2 0 bZIP transcription factor RHD_DNA_bind PF00554.22 OWF45658.1 - 1.1e-55 188.2 0.1 2e-55 187.3 0.1 1.5 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 OWF45658.1 - 2.4e-38 130.3 0.1 5.1e-38 129.2 0.1 1.6 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.7 OWF45658.1 - 3.1e-23 82.2 5.0 8.4e-12 45.5 0.7 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF45658.1 - 3.5e-20 71.8 6.6 7.9e-07 29.2 0.3 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF45658.1 - 3.1e-19 69.1 4.5 0.00028 21.4 0.0 5.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF45658.1 - 1.4e-18 66.4 14.1 0.00091 19.6 0.1 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OWF45658.1 - 2.9e-16 57.9 5.6 0.013 16.0 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Death PF00531.22 OWF45658.1 - 3.2e-07 30.4 0.0 1.2e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Death domain LigB PF02900.18 OWF45659.1 - 1.2e-33 116.4 0.0 1.3e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Neur_chan_LBD PF02931.23 OWF45660.1 - 2.6e-49 167.6 2.0 4.7e-49 166.7 2.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45660.1 - 2.7e-19 70.2 5.6 3e-16 60.2 5.6 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF996 PF06195.13 OWF45660.1 - 2.6 8.3 8.8 1.1 9.6 5.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Neur_chan_LBD PF02931.23 OWF45661.1 - 2.9e-48 164.2 3.3 4.3e-48 163.6 3.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45661.1 - 7.8e-19 68.7 5.9 1.3e-15 58.2 1.1 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HycA_repressor PF11046.8 OWF45661.1 - 0.038 14.2 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Neur_chan_LBD PF02931.23 OWF45662.1 - 5.8e-48 163.2 3.0 9.2e-48 162.5 3.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45662.1 - 8.9e-19 68.5 6.5 1.1e-15 58.4 0.5 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HycA_repressor PF11046.8 OWF45662.1 - 0.0085 16.3 1.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 1 Transcriptional repressor of hyc and hyp operons Neur_chan_LBD PF02931.23 OWF45663.1 - 9e-49 165.8 2.0 1.4e-48 165.2 2.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF45663.1 - 2.2e-18 67.2 6.6 1.1e-15 58.3 1.1 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HycA_repressor PF11046.8 OWF45663.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons LLGL PF08366.13 OWF45664.1 - 4.3e-39 133.0 2.5 1.2e-38 131.6 0.0 2.9 3 0 0 3 3 3 1 LLGL2 RAB3GAP2_N PF14655.6 OWF45664.1 - 3.5e-09 36.4 4.0 0.17 11.1 0.0 5.5 5 2 0 6 6 6 3 Rab3 GTPase-activating protein regulatory subunit N-terminus ANAPC4_WD40 PF12894.7 OWF45664.1 - 5.2e-09 36.3 0.1 0.58 10.5 0.0 6.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF45664.1 - 1e-07 32.5 0.0 0.31 12.0 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Lgl_C PF08596.10 OWF45664.1 - 0.0001 21.1 7.2 0.00054 18.8 0.0 3.6 4 0 0 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal BBS1 PF14779.6 OWF45664.1 - 0.0029 17.1 0.0 0.024 14.1 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 WD40_like PF17005.5 OWF45664.1 - 0.003 16.9 1.0 0.41 9.9 0.1 3.6 3 1 1 4 4 4 1 WD40-like domain RBD-FIP PF09457.10 OWF45665.1 - 3.2e-12 46.2 1.5 3.2e-12 46.2 1.5 2.4 2 0 0 2 2 1 1 FIP domain EF-hand_9 PF14658.6 OWF45665.1 - 1.3e-08 35.0 0.0 4.9e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OWF45665.1 - 1.9e-07 30.1 0.8 0.015 14.8 0.0 3.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OWF45665.1 - 3.6e-07 30.5 0.1 3.6e-07 30.5 0.1 3.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF45665.1 - 9.1e-05 22.2 2.0 0.00061 19.6 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF45665.1 - 0.00021 20.9 4.1 0.15 12.1 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain HALZ PF02183.18 OWF45665.1 - 0.0018 18.4 3.6 0.0018 18.4 3.6 6.7 6 1 1 7 7 7 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 OWF45665.1 - 0.013 15.6 1.9 0.013 15.6 1.9 5.4 3 2 2 5 5 5 0 bZIP transcription factor DUF1192 PF06698.11 OWF45665.1 - 0.11 12.6 2.9 3.8 7.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Shugoshin_N PF07558.11 OWF45665.1 - 0.15 12.0 0.1 0.15 12.0 0.1 4.7 5 1 1 6 6 6 0 Shugoshin N-terminal coiled-coil region BRI3BP PF14965.6 OWF45665.1 - 0.18 11.3 0.9 4.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Phage_head_chap PF11113.8 OWF45665.1 - 0.22 11.6 0.7 26 5.0 0.0 3.1 3 0 0 3 3 3 0 Head assembly gene product FUSC PF04632.12 OWF45665.1 - 0.3 9.5 7.6 0.46 9.0 7.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.25 OWF45665.1 - 0.71 9.5 27.2 0.019 14.7 12.7 3.0 2 1 1 3 3 3 0 Syntaxin DASH_Dam1 PF08653.10 OWF45665.1 - 0.92 9.4 4.5 15 5.5 0.3 3.8 3 1 0 3 3 3 0 DASH complex subunit Dam1 LPP PF04728.13 OWF45665.1 - 1.2 9.5 8.4 12 6.4 0.1 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 OWF45665.1 - 3.3 8.2 13.9 2.8 8.4 0.1 4.7 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 OWF45665.1 - 3.7 7.4 21.4 0.38 10.5 0.7 4.8 4 2 0 4 4 4 0 Septum formation initiator Exonuc_VII_L PF02601.15 OWF45665.1 - 5.3 6.5 23.8 3.8e+02 0.4 23.8 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 OWF45665.1 - 5.7 7.6 26.8 0.96 10.1 5.6 3.9 2 1 1 3 3 3 0 Initiation control protein YabA NPV_P10 PF05531.12 OWF45665.1 - 6.2 7.4 12.6 15 6.2 5.3 4.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 OWF45665.1 - 7.5 6.6 39.1 0.08 13.0 17.3 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NUDIX PF00293.28 OWF45666.1 - 0.00057 19.9 0.1 0.0018 18.3 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain NADH_u_ox_C PF12853.7 OWF45666.1 - 0.16 12.0 0.4 0.67 10.0 0.1 2.1 3 0 0 3 3 3 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Radial_spoke PF04712.12 OWF45667.1 - 2.5e-15 56.4 0.7 8.9e-08 31.5 1.2 2.5 1 1 1 2 2 2 2 Radial spokehead-like protein CCCAP PF15964.5 OWF45668.1 - 2.4e-95 320.3 82.2 9.2e-94 315.1 82.2 2.0 1 1 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family SHE3 PF17078.5 OWF45668.1 - 5.3 6.7 69.9 0.38 10.4 17.9 6.0 2 2 3 5 5 5 0 SWI5-dependent HO expression protein 3 Pkinase_Tyr PF07714.17 OWF45670.1 - 1e-05 25.0 0.0 2.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF45670.1 - 2.7e-05 23.7 0.4 9.9e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 OWF45670.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1331 PF07048.11 OWF45670.1 - 0.14 11.8 0.7 3.2 7.5 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) DUF420 PF04238.12 OWF45670.1 - 0.24 11.7 1.9 0.64 10.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF420) DUF1218 PF06749.12 OWF45670.1 - 2.8 8.5 9.1 0.12 12.9 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) 7tm_1 PF00001.21 OWF45670.1 - 4.7 6.5 13.9 7.6 5.8 13.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RHD_DNA_bind PF00554.22 OWF45671.1 - 8.8e-05 22.5 0.2 0.0002 21.4 0.2 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 OWF45671.1 - 0.00079 19.4 2.3 0.00081 19.4 0.3 2.0 2 0 0 2 2 2 1 Rel homology dimerisation domain ELO PF01151.18 OWF45672.1 - 2.4e-52 178.0 22.4 3e-52 177.7 22.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Sel1 PF08238.12 OWF45673.1 - 9.3e-49 162.8 36.5 3.6e-09 37.0 0.2 12.0 13 0 0 13 13 13 9 Sel1 repeat Flu_M1_C PF08289.11 OWF45673.1 - 0.046 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Death PF00531.22 OWF45674.1 - 0.0048 17.0 0.9 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Death domain Cob_adeno_trans PF01923.18 OWF45674.1 - 0.088 12.9 1.3 0.15 12.2 1.3 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase bZIP_2 PF07716.15 OWF45674.1 - 0.1 12.7 7.7 0.65 10.1 0.3 2.5 2 0 0 2 2 2 0 Basic region leucine zipper TolA_bind_tri PF16331.5 OWF45674.1 - 0.11 12.6 4.2 4.6 7.4 0.1 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation HALZ PF02183.18 OWF45674.1 - 0.14 12.4 0.6 0.14 12.4 0.6 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper CLZ PF16526.5 OWF45674.1 - 0.16 12.4 6.4 0.66 10.4 1.1 2.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Allexi_40kDa PF05549.11 OWF45674.1 - 0.21 11.1 2.7 0.4 10.2 2.6 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein PilJ PF13675.6 OWF45674.1 - 0.46 10.5 2.9 4.1 7.5 0.7 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term SlyX PF04102.12 OWF45674.1 - 0.9 10.2 3.6 3.5 8.3 0.7 2.7 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 OWF45674.1 - 2.1 8.8 6.2 11 6.5 0.7 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Adap_comp_sub PF00928.21 OWF45676.1 - 1.6e-50 171.9 0.0 3.2e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Acyltransferase PF01553.21 OWF45677.1 - 6.8e-20 71.1 0.0 1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OWF45677.1 - 1.4e-12 47.5 0.4 2.8e-12 46.5 0.4 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Metallophos PF00149.28 OWF45678.1 - 9.8e-24 85.0 1.2 1.5e-23 84.4 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OWF45678.1 - 8.8e-22 77.7 0.1 3.1e-21 76.0 0.1 2.1 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OWF45678.1 - 6.3e-18 65.1 0.9 1.4e-17 64.0 0.9 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 OWF45678.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.21 OWF45678.1 - 0.039 14.3 0.3 0.081 13.3 0.3 1.5 1 0 0 1 1 1 0 Fibronectin type III domain FOXP-CC PF16159.5 OWF45679.1 - 2.2e-27 95.4 5.2 2.2e-27 95.4 5.2 4.1 2 1 2 4 4 4 1 FOXP coiled-coil domain Forkhead PF00250.18 OWF45679.1 - 2.4e-27 95.0 0.4 2.4e-27 95.0 0.4 2.0 2 0 0 2 2 2 1 Forkhead domain Bmt2 PF11968.8 OWF45680.1 - 0.00075 19.4 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF2332 PF10094.9 OWF45680.1 - 0.022 14.2 0.0 0.066 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2332) Methyltransf_12 PF08242.12 OWF45680.1 - 0.09 13.5 0.0 1.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Spore_YabQ PF09578.10 OWF45681.1 - 6.1 7.1 10.2 14 6.0 1.3 3.3 2 1 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF1885 PF08968.10 OWF45682.1 - 9.7e-19 67.8 74.4 5.2 7.2 0.3 21.3 1 1 30 32 32 32 28 Domain of unknown function (DUF1885) DUF1905 PF08922.11 OWF45682.1 - 1e-17 64.0 0.3 52 4.0 0.0 20.1 4 3 8 12 12 12 0 Domain of unknown function (DUF1905) Cornifin PF02389.15 OWF45682.1 - 1.3e-17 64.3 0.0 0.034 14.3 0.0 9.3 1 1 9 11 11 11 9 Cornifin (SPRR) family DSPc PF00782.20 OWF45682.1 - 7.1e-06 25.9 50.6 1e+02 2.7 0.6 20.2 1 1 5 7 7 7 0 Dual specificity phosphatase, catalytic domain Cyc-maltodext_N PF09087.11 OWF45682.1 - 0.037 14.3 66.1 8.3 6.8 0.3 16.0 1 1 26 27 27 27 0 Cyclomaltodextrinase, N-terminal IgGFc_binding PF17517.2 OWF45683.1 - 7.7e-36 123.9 4.7 1.2e-35 123.3 4.7 1.3 1 0 0 1 1 1 1 IgGFc binding protein EGF_CA PF07645.15 OWF45684.1 - 2.1e-51 171.9 146.8 1.1e-09 38.3 7.8 10.2 8 4 1 9 9 9 8 Calcium-binding EGF domain EGF PF00008.27 OWF45684.1 - 6.8e-49 163.8 133.0 1.2e-09 38.3 8.0 10.9 10 1 0 10 10 10 8 EGF-like domain hEGF PF12661.7 OWF45684.1 - 3.9e-24 84.4 132.9 9e-06 26.1 5.1 11.3 10 0 0 10 10 10 8 Human growth factor-like EGF EGF_2 PF07974.13 OWF45684.1 - 2.2e-14 53.5 175.3 0.00048 20.4 13.3 10.7 10 1 2 12 12 12 8 EGF-like domain EGF_3 PF12947.7 OWF45684.1 - 3.2e-05 24.0 135.3 0.1 12.8 7.4 10.0 9 1 0 9 9 9 6 EGF domain FXa_inhibition PF14670.6 OWF45684.1 - 4.9e-05 23.5 125.5 0.3 11.4 9.0 10.6 4 3 6 10 10 10 6 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 OWF45684.1 - 4.3 7.5 112.5 0.052 13.6 6.5 9.0 8 1 0 8 8 8 0 MSP1 EGF domain 1 EGF PF00008.27 OWF45686.1 - 2.4e-28 98.1 74.7 2.5e-06 27.7 6.0 6.7 6 1 0 6 6 6 6 EGF-like domain EGF_2 PF07974.13 OWF45686.1 - 8.8e-16 58.0 90.6 0.00017 21.9 4.5 6.4 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 OWF45686.1 - 5.6e-15 55.3 89.7 2.3e-05 24.8 7.3 8.5 9 0 0 9 9 9 6 Human growth factor-like EGF EGF_CA PF07645.15 OWF45686.1 - 9.5e-12 44.9 77.8 3.8e-07 30.2 9.8 6.3 2 1 4 6 6 6 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF45686.1 - 1.1e-05 25.6 72.6 0.95 9.8 10.4 6.7 3 2 3 6 6 6 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 OWF45686.1 - 0.0015 18.6 68.4 0.036 14.3 5.8 7.3 4 3 2 6 6 6 4 EGF domain TMEM154 PF15102.6 OWF45686.1 - 0.052 13.4 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 OWF45686.1 - 0.15 12.9 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Laminin_EGF PF00053.24 OWF45686.1 - 0.46 10.7 68.4 0.59 10.3 6.7 6.3 2 1 3 6 6 6 0 Laminin EGF domain Exo_endo_phos PF03372.23 OWF45687.1 - 2.9e-08 33.5 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OWF45687.1 - 0.0028 17.5 0.8 0.017 14.9 0.7 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase DUF3285 PF11688.8 OWF45688.1 - 0.74 9.8 2.4 4.9 7.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) CBM_14 PF01607.24 OWF45689.1 - 8.3e-08 32.3 1.0 8.3e-08 32.3 1.0 2.8 2 1 0 2 2 2 1 Chitin binding Peritrophin-A domain PRCC PF10253.9 OWF45689.1 - 0.38 11.5 5.1 0.42 11.4 5.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CDC27 PF09507.10 OWF45689.1 - 3.2 7.0 10.7 4.2 6.7 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDV3 PF15359.6 OWF45689.1 - 5.8 7.4 9.4 8.9 6.8 9.4 1.2 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Dicty_REP PF05086.12 OWF45689.1 - 9 4.1 12.3 12 3.8 12.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SNF PF00209.18 OWF45690.1 - 3.2e-168 560.7 23.5 3.9e-168 560.4 23.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF45691.1 - 1.3e-45 156.1 9.3 1.5e-45 155.9 9.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4690 PF15756.5 OWF45692.1 - 0.015 15.8 0.6 0.015 15.8 0.6 1.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Tim17 PF02466.19 OWF45692.1 - 0.042 14.2 0.5 0.076 13.4 0.5 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family EphA2_TM PF14575.6 OWF45692.1 - 0.11 13.4 0.1 0.22 12.4 0.1 1.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 OWF45692.1 - 1.5 9.3 11.6 1.9 8.9 11.5 1.3 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 FixS PF03597.15 OWF45692.1 - 4 7.2 4.8 8.7 6.1 4.8 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Filamin PF00630.19 OWF45693.1 - 0 1189.9 79.2 4.2e-19 69.3 0.0 24.1 24 0 0 24 24 24 24 Filamin/ABP280 repeat CH PF00307.31 OWF45693.1 - 6e-38 129.4 1.5 8.3e-22 77.4 0.9 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 OWF45693.1 - 2e-15 56.5 24.8 0.1 12.5 0.0 15.0 18 0 0 18 18 16 3 Y_Y_Y domain DUF5060 PF16586.5 OWF45693.1 - 5.5e-12 45.9 0.0 46 4.5 0.0 13.4 16 0 0 16 16 16 0 Domain of unknown function (DUF5060) Big_3_5 PF16640.5 OWF45693.1 - 3.7e-10 39.9 44.7 2.3 8.5 0.1 17.3 19 1 0 19 19 19 3 Bacterial Ig-like domain (group 3) YtkA PF13115.6 OWF45693.1 - 1.1e-08 35.6 13.3 2.5 8.8 0.0 12.5 13 0 0 13 13 13 1 YtkA-like PKD PF00801.20 OWF45693.1 - 4.2e-07 29.7 13.4 12 5.8 0.0 11.1 11 0 0 11 11 11 0 PKD domain Invasin_D3 PF09134.10 OWF45693.1 - 1.4e-06 28.5 28.0 0.88 9.9 0.2 12.0 14 0 0 14 14 14 1 Invasin, domain 3 CAMSAP_CH PF11971.8 OWF45693.1 - 0.0017 18.2 0.1 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain Big_3 PF07523.12 OWF45693.1 - 0.021 15.1 36.2 5.3 7.4 0.0 14.0 15 3 3 18 18 16 0 Bacterial Ig-like domain (group 3) ASH PF15780.5 OWF45693.1 - 0.022 14.9 0.4 17 5.7 0.1 6.0 6 0 0 6 6 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Cupredoxin_1 PF13473.6 OWF45693.1 - 0.078 13.1 2.0 22 5.2 0.0 5.9 6 0 0 6 6 6 0 Cupredoxin-like domain Inhibitor_I42 PF09394.10 OWF45693.1 - 0.13 12.6 9.7 93 3.5 0.0 9.7 13 1 0 13 13 11 0 Chagasin family peptidase inhibitor I42 DUF4369 PF14289.6 OWF45693.1 - 0.34 11.4 6.8 5.2 7.7 0.1 6.2 8 1 0 8 8 5 0 Domain of unknown function (DUF4369) DUF4974 PF16344.5 OWF45693.1 - 1.4 9.0 3.9 1.8e+02 2.2 0.0 5.5 7 0 0 7 7 6 0 Domain of unknown function (DUF4974) He_PIG PF05345.12 OWF45693.1 - 3.2 8.0 28.0 8.4 6.7 0.0 10.7 11 1 0 11 11 11 0 Putative Ig domain FHA PF00498.26 OWF45694.1 - 2.3e-16 59.9 0.0 7.3e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OWF45694.1 - 0.0045 17.3 0.0 0.049 14.0 0.0 2.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF3575 PF12099.8 OWF45694.1 - 0.19 11.0 0.1 0.34 10.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) DUF3539 PF12058.8 OWF45694.1 - 3.5 7.8 6.1 13 6.0 0.4 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3539) SPA PF08616.10 OWF45695.1 - 2.4e-14 53.2 0.0 4.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 OWF45695.1 - 1.7e-06 28.1 2.5 6e-06 26.3 1.1 2.4 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 OWF45695.1 - 1.3e-05 24.0 0.1 2.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.6 OWF45695.1 - 0.032 14.8 0.1 0.071 13.7 0.1 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Ion_trans_2 PF07885.16 OWF45696.1 - 7.2e-29 99.6 24.2 5.9e-15 55.0 8.4 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF45696.1 - 6.9e-05 22.2 20.4 7.9e-05 22.0 3.7 2.3 2 0 0 2 2 2 2 Ion transport protein LPG_synthase_TM PF03706.13 OWF45696.1 - 0.017 14.7 1.5 0.029 13.9 0.5 1.8 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region DUF4044 PF13253.6 OWF45696.1 - 0.27 10.8 1.6 0.95 9.0 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) WBP-1 PF11669.8 OWF45696.1 - 0.47 11.1 4.0 9.1 7.0 0.1 3.1 3 0 0 3 3 3 0 WW domain-binding protein 1 Lipase_GDSL_2 PF13472.6 OWF45697.1 - 3.2e-09 37.5 0.0 3.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF45697.1 - 1.1e-08 35.3 0.0 1.3e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2173 PF09941.9 OWF45698.1 - 6.3e-15 55.4 45.3 0.0082 16.4 0.6 8.2 1 1 7 8 8 8 8 Uncharacterized conserved protein (DUF2173) TRPM_tetra PF16519.5 OWF45698.1 - 1.7e-11 44.0 23.3 0.32 11.1 0.7 8.2 1 1 8 9 9 9 7 Tetramerisation domain of TRPM Snapin_Pallidin PF14712.6 OWF45698.1 - 1.1e-07 32.2 18.8 3.4 8.2 0.2 7.9 2 2 6 8 8 8 1 Snapin/Pallidin Laminin_II PF06009.12 OWF45698.1 - 1.8e-07 31.3 0.0 0.8 9.7 0.0 4.1 1 1 4 5 5 5 3 Laminin Domain II DUF948 PF06103.11 OWF45698.1 - 4.3e-06 26.9 11.1 2.8 8.3 0.3 6.3 1 1 4 5 5 5 1 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 OWF45698.1 - 4.9e-06 25.8 3.1 0.0025 16.9 0.1 2.6 1 1 2 3 3 3 2 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 OWF45698.1 - 9.2e-06 25.7 0.1 0.12 12.5 0.0 3.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus RmuC PF02646.16 OWF45698.1 - 3e-05 23.3 0.0 1.1 8.4 0.0 3.7 1 1 3 4 4 4 2 RmuC family PEARLI-4 PF05278.12 OWF45698.1 - 3.7e-05 23.5 7.6 1.8 8.1 0.5 5.4 1 1 5 6 6 6 2 Arabidopsis phospholipase-like protein (PEARLI 4) Laminin_I PF06008.14 OWF45698.1 - 0.00021 21.1 0.0 1.4 8.6 0.0 3.7 1 1 3 4 4 4 1 Laminin Domain I DUF2333 PF10095.9 OWF45698.1 - 0.00025 20.2 0.0 2.4 7.1 0.0 3.7 1 1 6 7 7 7 2 Uncharacterized protein conserved in bacteria (DUF2333) DUF724 PF05266.14 OWF45698.1 - 0.00051 19.9 0.1 0.76 9.6 0.2 3.3 1 1 1 2 2 2 1 Protein of unknown function (DUF724) LegC3_N PF18654.1 OWF45698.1 - 0.00083 18.7 0.7 12 5.1 0.1 3.9 1 1 3 4 4 4 0 LegC3 N-terminal coiled-coil domain MscS_porin PF12795.7 OWF45698.1 - 0.00089 18.9 0.0 8.3 5.9 0.0 3.8 1 1 4 5 5 5 0 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.19 OWF45698.1 - 0.0015 16.4 0.0 0.028 12.3 0.0 1.9 1 1 1 2 2 2 2 Myosin tail DUF1664 PF07889.12 OWF45698.1 - 0.0021 18.1 7.0 2.8 8.0 0.8 3.8 1 1 4 5 5 5 4 Protein of unknown function (DUF1664) DUF4097 PF13349.6 OWF45698.1 - 0.014 14.8 3.1 0.28 10.5 3.1 2.8 1 1 0 1 1 1 0 Putative adhesin DUF3370 PF11850.8 OWF45698.1 - 0.02 13.8 0.0 18 4.1 0.0 4.3 2 1 4 6 6 6 0 Protein of unknown function (DUF3370) EzrA PF06160.12 OWF45698.1 - 0.047 11.9 0.0 0.18 10.0 0.0 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA PapD-like PF14874.6 OWF45698.1 - 0.07 13.3 3.7 5.6 7.2 0.1 3.9 1 1 4 5 5 5 0 Flagellar-associated PapD-like ATPgrasp_Ter PF15632.6 OWF45698.1 - 0.16 11.8 24.4 69 3.2 0.1 8.8 1 1 7 9 9 9 0 ATP-grasp in the biosynthetic pathway with Ter operon Fibritin_C PF07921.12 OWF45698.1 - 7.9 6.7 18.7 77 3.5 0.1 6.6 7 1 0 7 7 7 0 Fibritin C-terminal region Ubiquitin_2 PF14560.6 OWF45699.1 - 1.5e-28 99.0 0.0 3.5e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 OWF45699.1 - 6.6e-23 80.5 1.3 1.1e-22 79.7 0.7 1.7 2 0 0 2 2 2 1 CAP-Gly domain T6_Ig_like PF18002.1 OWF45699.1 - 0.047 13.6 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 T6 antigen Ig like domain BIRC6 PF12356.8 OWF45700.1 - 6.4e-52 175.5 1.3 6.4e-52 175.5 1.3 2.5 2 0 0 2 2 2 1 Baculoviral IAP repeat-containing protein 6 UQ_con PF00179.26 OWF45700.1 - 1.3e-29 102.7 0.0 4e-29 101.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BIR PF00653.21 OWF45700.1 - 5.9e-20 71.7 3.7 1.6e-19 70.3 3.7 1.8 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UEV PF05743.13 OWF45700.1 - 1.5e-05 24.9 0.4 4.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 UEV domain RWD PF05773.22 OWF45700.1 - 0.043 14.1 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 RWD domain DUF1720 PF08226.11 OWF45701.1 - 1.1e-05 25.7 12.8 1.4 9.3 4.1 4.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1720) zf-DBF PF07535.12 OWF45701.1 - 4.4e-05 23.5 12.9 2.6e+02 1.9 0.0 9.9 11 0 0 11 11 11 0 DBF zinc finger GCP_N_terminal PF17681.1 OWF45701.1 - 0.23 11.1 12.0 5.8 6.5 1.9 3.2 1 1 2 3 3 3 0 Gamma tubulin complex component N-terminal Cys_knot PF00007.22 OWF45701.1 - 0.36 11.2 9.2 19 5.6 0.4 3.0 1 1 1 3 3 3 0 Cystine-knot domain Ten1 PF12658.7 OWF45701.1 - 2.3 8.2 16.1 73 3.3 0.2 7.0 1 1 7 8 8 8 0 Telomere capping, CST complex subunit RRM_1 PF00076.22 OWF45702.1 - 3.6e-13 49.1 0.0 7.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF45702.1 - 0.00047 20.2 0.0 0.00097 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 OWF45702.1 - 0.0018 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF45702.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ank_2 PF12796.7 OWF45703.1 - 5.6e-87 286.4 25.5 1.2e-15 57.8 0.1 13.9 10 3 5 15 15 15 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF45703.1 - 6.5e-85 278.5 18.8 1.2e-07 32.1 0.0 19.4 13 4 8 21 21 21 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF45703.1 - 3.4e-61 196.0 23.9 0.00078 19.7 0.0 23.7 25 0 0 25 25 25 15 Ankyrin repeat Ank_5 PF13857.6 OWF45703.1 - 5.3e-60 198.7 25.3 5.1e-06 26.7 0.2 18.4 13 6 3 17 17 17 12 Ankyrin repeats (many copies) Ank PF00023.30 OWF45703.1 - 2.4e-58 192.2 34.6 0.01 16.3 0.1 22.6 23 0 0 23 23 23 16 Ankyrin repeat PARP PF00644.20 OWF45703.1 - 2.7e-34 118.5 2.8 3.1e-34 118.3 0.0 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OWF45703.1 - 1.1e-24 87.1 1.1 3.2e-24 85.6 1.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OWF45703.1 - 7.5e-20 70.8 0.5 2.3e-19 69.2 0.5 1.9 1 0 0 1 1 1 1 WGR domain DotD PF16816.5 OWF45703.1 - 0.11 12.5 0.1 0.33 10.9 0.1 1.8 1 0 0 1 1 1 0 DotD protein ABA_WDS PF02496.16 OWF45704.1 - 0.051 14.1 0.1 0.088 13.3 0.1 1.3 1 0 0 1 1 1 0 ABA/WDS induced protein Peptidase_S9 PF00326.21 OWF45705.1 - 7.6e-45 153.0 0.1 2.2e-44 151.5 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OWF45705.1 - 2.3e-07 30.6 0.0 5.2e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 OWF45705.1 - 3.3e-05 22.7 0.1 0.0026 16.5 0.1 2.5 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF5050 PF16472.5 OWF45705.1 - 0.00021 20.6 0.0 0.0074 15.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5050) Peptidase_S15 PF02129.18 OWF45705.1 - 0.0043 16.7 0.0 1.1 8.7 0.0 2.4 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 OWF45705.1 - 0.0052 16.7 0.0 0.081 12.9 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 OWF45705.1 - 0.013 14.8 0.1 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OWF45705.1 - 0.13 12.1 0.1 0.69 9.7 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold CRM1_C PF08767.11 OWF45706.1 - 9.5e-132 439.0 4.3 9.5e-132 439.0 4.3 2.7 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OWF45706.1 - 1.5e-40 138.6 2.3 1.5e-40 138.6 2.3 5.5 6 1 1 7 7 7 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OWF45706.1 - 2.1e-37 126.6 1.6 7.6e-37 124.8 1.6 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OWF45706.1 - 7.8e-30 102.8 2.4 1.3e-29 102.0 0.7 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OWF45706.1 - 8.8e-19 66.7 4.2 2e-18 65.6 4.2 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OWF45706.1 - 1e-11 44.6 0.1 1e-11 44.6 0.1 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 OWF45706.1 - 0.00055 20.5 4.2 2.4 8.8 0.1 5.8 4 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region zf-C2H2 PF00096.26 OWF45707.1 - 2.2e-24 84.5 46.4 1.7e-05 25.0 0.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF45707.1 - 3e-23 81.1 56.5 1.3e-08 34.9 0.9 7.0 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF45707.1 - 7.1e-15 54.4 43.4 0.0043 17.8 0.3 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF45707.1 - 1.8e-06 27.6 17.8 0.0085 15.8 0.8 5.5 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 OWF45707.1 - 0.00028 21.1 22.3 0.00069 19.8 0.1 5.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF45707.1 - 0.0048 16.9 0.3 0.0048 16.9 0.3 6.2 6 0 0 6 6 5 2 C2H2-type zinc finger zf-met PF12874.7 OWF45707.1 - 0.0067 16.8 20.8 0.13 12.7 0.3 5.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF45707.1 - 0.0077 16.5 22.5 0.45 10.9 5.7 3.7 1 1 3 4 4 4 4 C2H2-type zinc ribbon zf-RING_7 PF02591.15 OWF45707.1 - 0.012 15.8 0.4 2.1 8.6 0.0 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-DNA_Pol PF08996.10 OWF45707.1 - 0.1 12.4 14.4 0.2 11.4 1.0 3.1 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger FYDLN_acid PF09538.10 OWF45707.1 - 0.3 11.8 11.8 0.27 12.0 1.5 3.4 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf_UBZ PF18439.1 OWF45707.1 - 5.9 6.6 16.3 0.93 9.1 0.1 4.7 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger UPF0564 PF10595.9 OWF45708.1 - 9.7e-70 235.4 52.0 2.2e-69 234.3 52.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 FAD_binding_3 PF01494.19 OWF45709.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OWF45709.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase AAA_16 PF13191.6 OWF45710.1 - 2.3e-06 28.1 0.0 2.7e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OWF45710.1 - 2.6e-05 24.2 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase DUF815 PF05673.13 OWF45710.1 - 0.00016 20.9 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 OWF45710.1 - 0.00039 20.9 0.1 0.00056 20.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OWF45710.1 - 0.00085 19.4 0.8 0.0014 18.7 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OWF45710.1 - 0.0037 17.6 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 OWF45710.1 - 0.0047 16.6 0.7 0.015 15.0 0.5 1.8 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OWF45710.1 - 0.0064 16.8 0.0 0.0076 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OWF45710.1 - 0.0069 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region IIGP PF05049.13 OWF45710.1 - 0.009 15.1 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 OWF45710.1 - 0.0093 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.6 OWF45710.1 - 0.014 14.9 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OWF45710.1 - 0.015 15.5 0.0 0.05 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OWF45710.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 OWF45710.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 OWF45710.1 - 0.024 13.9 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Septin Roc PF08477.13 OWF45710.1 - 0.026 14.7 0.6 0.035 14.3 0.0 1.5 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OWF45710.1 - 0.027 13.6 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 OWF45710.1 - 0.028 14.1 0.1 0.14 11.9 0.0 1.8 1 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF45710.1 - 0.03 14.2 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 OWF45710.1 - 0.055 12.9 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_21 PF13304.6 OWF45710.1 - 0.055 13.3 0.2 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 OWF45710.1 - 0.071 13.0 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Collar PF07484.12 OWF45710.1 - 0.092 12.8 0.1 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Phage Tail Collar Domain AAA PF00004.29 OWF45710.1 - 0.099 13.1 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OWF45710.1 - 0.099 13.1 1.5 0.29 11.6 0.7 2.0 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 OWF45710.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.22 OWF45710.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras family TsaE PF02367.17 OWF45710.1 - 0.15 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AIG1 PF04548.16 OWF45710.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Adeno_IVa2 PF02456.15 OWF45710.1 - 0.18 10.5 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 OWF45710.1 - 0.5 10.4 2.6 0.55 10.3 0.1 2.2 3 0 0 3 3 3 0 Dynamin family RNA_pol_Rpb1_R PF05001.13 OWF45711.1 - 1.5e-07 31.4 214.5 0.05 14.0 16.0 12.8 8 1 6 15 15 15 11 RNA polymerase Rpb1 C-terminal repeat LRR_6 PF13516.6 OWF45712.1 - 2.6e-14 52.0 20.6 0.0021 18.0 0.0 8.7 10 0 0 10 10 10 6 Leucine Rich repeat EF-hand_7 PF13499.6 OWF45712.1 - 5.3e-10 39.6 0.5 2.2e-09 37.6 0.5 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF45712.1 - 4.4e-07 29.3 1.8 0.01 15.7 0.4 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF45712.1 - 4.2e-06 25.9 2.0 0.07 12.7 0.6 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OWF45712.1 - 6.1e-06 25.5 4.8 0.019 14.4 0.6 3.2 3 0 0 3 3 3 2 EF hand LRR_1 PF00560.33 OWF45712.1 - 2.4e-05 24.3 5.6 18 6.4 0.0 7.5 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 OWF45712.1 - 0.0014 19.0 11.6 0.78 10.3 0.2 5.7 6 1 0 6 6 6 1 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 OWF45712.1 - 0.0069 16.2 1.2 0.075 12.9 0.2 2.8 1 1 1 2 2 2 1 EF-hand domain pair zf-B_box PF00643.24 OWF45713.1 - 5 7.4 43.1 4.2 7.6 0.9 5.1 2 1 2 4 4 4 0 B-box zinc finger LRR_6 PF13516.6 OWF45714.1 - 2.5e-17 61.4 18.4 0.0052 16.7 0.0 8.2 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 OWF45714.1 - 1.4e-09 38.0 10.9 0.00033 21.0 0.0 5.5 4 3 1 5 5 5 2 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 OWF45714.1 - 5.6e-09 36.3 0.8 1.4e-08 35.1 0.8 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF45714.1 - 6.1e-07 28.9 2.4 0.027 14.4 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain LRR_1 PF00560.33 OWF45714.1 - 2.8e-06 27.1 9.3 12 6.9 0.0 7.5 8 0 0 8 8 7 1 Leucine Rich Repeat EF-hand_1 PF00036.32 OWF45714.1 - 3e-06 26.4 5.4 0.0093 15.5 1.6 2.6 2 0 0 2 2 2 2 EF hand LRR_8 PF13855.6 OWF45714.1 - 5.5e-06 26.1 7.2 0.0027 17.4 0.5 5.3 4 2 0 4 4 4 1 Leucine rich repeat EF-hand_8 PF13833.6 OWF45714.1 - 0.0018 18.1 2.0 0.0079 16.0 1.0 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF45714.1 - 0.0087 15.5 5.3 0.037 13.5 0.8 2.6 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 OWF45714.1 - 0.039 13.9 0.2 0.088 12.8 0.2 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand RAM PF15320.6 OWF45714.1 - 0.18 12.4 1.6 0.18 12.4 0.1 1.8 2 0 0 2 2 1 0 mRNA cap methylation, RNMT-activating mini protein AHD PF17793.1 OWF45714.1 - 0.2 11.5 1.8 8.2 6.3 0.5 3.0 3 0 0 3 3 2 0 ANC1 homology domain (AHD) SPARC_Ca_bdg PF10591.9 OWF45714.1 - 0.26 11.6 2.1 0.4 11.0 0.1 2.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region HSP70 PF00012.20 OWF45715.1 - 6.3e-252 837.1 7.1 7.2e-252 836.9 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF45715.1 - 4.5e-17 61.9 0.1 5.7e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OWF45715.1 - 0.0026 18.1 3.1 1.2 9.6 0.2 3.2 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 OWF45715.1 - 0.0087 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 OWF45715.1 - 0.017 14.6 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 OWF45715.1 - 0.066 12.5 1.0 0.34 10.1 0.2 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF3153 PF11353.8 OWF45715.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) PIH1_CS PF18201.1 OWF45716.1 - 5.4e-09 36.4 0.0 8.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain Fasciclin PF02469.22 OWF45717.1 - 2.8e-56 189.2 4.4 1.3e-27 96.5 1.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF2671 PF10877.8 OWF45717.1 - 0.063 13.1 0.3 0.44 10.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2671) BTB PF00651.31 OWF45718.1 - 3.4e-13 49.8 0.0 7.9e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF3304 PF11745.8 OWF45718.1 - 0.094 13.1 0.0 0.094 13.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3304) Fasciclin PF02469.22 OWF45719.1 - 7.2e-65 217.0 0.0 7.9e-33 113.4 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain AlaDh_PNT_N PF05222.15 OWF45719.1 - 0.055 13.8 0.1 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain HCBP_related PF06594.11 OWF45719.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain Fasciclin PF02469.22 OWF45720.1 - 7.6e-53 178.1 1.1 1.8e-27 96.1 0.1 2.0 2 0 0 2 2 2 2 Fasciclin domain Glyco_tran_28_C PF04101.16 OWF45720.1 - 0.11 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Lipocalin_2 PF08212.12 OWF45721.1 - 4.8e-06 26.6 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain SRCR PF00530.18 OWF45722.1 - 5.7e-56 187.2 9.3 1.2e-27 96.3 2.3 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_b PF00058.17 OWF45722.1 - 1.1e-50 169.8 15.3 1.2e-08 35.3 0.1 10.3 10 0 0 10 10 10 7 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 OWF45722.1 - 5.6e-26 91.4 0.5 1.9e-08 33.9 0.1 4.1 2 2 2 4 4 4 4 Domain of unknown function (DUF5050) SGL PF08450.12 OWF45722.1 - 4.3e-12 46.1 12.0 0.00037 20.2 1.2 5.2 2 2 4 6 6 6 4 SMP-30/Gluconolactonase/LRE-like region SRCR_2 PF15494.6 OWF45722.1 - 7.9e-11 42.4 2.4 7.4e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain NHL PF01436.21 OWF45722.1 - 3.5e-05 23.6 0.3 10 6.4 0.0 6.3 6 0 0 6 6 6 1 NHL repeat Arylesterase PF01731.20 OWF45722.1 - 5.4e-05 23.3 1.4 2.9 8.1 0.0 6.9 8 1 1 9 9 9 1 Arylesterase Lactonase PF10282.9 OWF45722.1 - 9.4e-05 21.8 1.5 2.1 7.5 0.0 5.3 2 2 0 4 4 4 1 Lactonase, 7-bladed beta-propeller Str_synth PF03088.16 OWF45722.1 - 0.033 14.3 0.1 35 4.6 0.0 4.9 5 2 2 7 7 7 0 Strictosidine synthase Hepsin-SRCR PF09272.10 OWF45722.1 - 0.058 13.9 0.1 7.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Hepsin, SRCR domain SRCR PF00530.18 OWF45724.1 - 9.8e-57 189.7 9.9 7.9e-29 100.1 1.5 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_b PF00058.17 OWF45724.1 - 3.7e-51 171.4 15.0 2.5e-09 37.5 0.1 10.3 10 0 0 10 10 10 7 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 OWF45724.1 - 1.3e-24 86.9 0.5 1.1e-08 34.7 0.3 3.8 2 2 2 4 4 4 4 Domain of unknown function (DUF5050) SRCR_2 PF15494.6 OWF45724.1 - 1.3e-11 44.9 1.3 5.9e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SGL PF08450.12 OWF45724.1 - 3.1e-11 43.3 11.6 0.0011 18.7 0.4 5.4 2 2 4 6 6 6 4 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OWF45724.1 - 7.1e-06 26.1 0.1 2.9 8.1 0.0 7.4 9 1 1 10 10 10 1 Arylesterase NHL PF01436.21 OWF45724.1 - 9e-05 22.3 0.3 10 6.4 0.0 6.3 6 0 0 6 6 6 1 NHL repeat Lactonase PF10282.9 OWF45724.1 - 0.00024 20.5 0.9 2.8 7.1 0.0 5.1 2 2 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Hepsin-SRCR PF09272.10 OWF45724.1 - 0.048 14.2 0.0 21 5.7 0.1 2.6 2 0 0 2 2 2 0 Hepsin, SRCR domain Str_synth PF03088.16 OWF45724.1 - 0.051 13.7 0.2 39 4.5 0.0 4.8 5 2 2 7 7 7 0 Strictosidine synthase Ribosomal_S3_C PF00189.20 OWF45725.1 - 1.6e-23 83.0 0.3 6.1e-23 81.1 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OWF45725.1 - 1.2e-11 44.3 0.1 2e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 KH domain Peptidase_C1 PF00112.23 OWF45726.1 - 1.8e-53 181.8 0.9 2.6e-53 181.3 0.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF45726.1 - 1.7e-14 54.0 7.8 3.2e-14 53.1 7.8 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF45726.1 - 2.4e-06 26.6 0.9 0.0011 17.9 0.0 2.5 2 1 0 2 2 2 2 Peptidase C1-like family AI-2E_transport PF01594.16 OWF45726.1 - 0.23 10.6 0.1 0.31 10.1 0.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter MRG PF05712.13 OWF45727.1 - 1.1e-43 148.9 0.0 1.9e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 OWF45727.1 - 0.0041 17.0 0.2 0.0077 16.1 0.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF229 PF02995.17 OWF45728.1 - 1.1e-34 119.9 3.3 2.2e-26 92.6 0.3 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF229) Humanin PF15040.6 OWF45728.1 - 0.0068 15.8 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 Humanin family Glutaredoxin PF00462.24 OWF45729.1 - 3.3e-08 33.6 2.3 4.7e-08 33.1 0.1 2.3 2 1 1 3 3 3 1 Glutaredoxin SH3BGR PF04908.15 OWF45729.1 - 0.007 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein MutS_II PF05188.17 OWF45729.1 - 0.013 15.7 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 MutS domain II zf-CHY PF05495.12 OWF45729.1 - 0.46 11.0 6.1 1 9.9 6.1 1.6 1 0 0 1 1 1 0 CHY zinc finger DnaJ_CXXCXGXG PF00684.19 OWF45729.1 - 0.71 10.3 7.2 3.1 8.2 2.5 2.2 1 1 1 2 2 2 0 DnaJ central domain DUF4592 PF15262.6 OWF45730.1 - 1.5e-07 32.1 2.9 1.5e-07 32.1 2.9 7.0 3 3 3 6 6 6 1 Domain of unknown function (DUF4592) Trypsin PF00089.26 OWF45733.1 - 2.6e-45 154.9 1.3 5.5e-45 153.9 0.1 2.2 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.18 OWF45733.1 - 2.1e-36 123.9 97.2 4.5e-08 33.2 9.0 6.8 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A SRCR_2 PF15494.6 OWF45733.1 - 5.4e-09 36.5 3.8 5.4e-09 36.5 3.8 3.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 OWF45733.1 - 4.1e-07 30.4 0.4 4.1e-07 30.4 0.4 2.8 2 1 1 3 3 3 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 OWF45733.1 - 5.8e-06 26.7 0.2 2.7e-05 24.5 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Homeodomain PF00046.29 OWF45734.1 - 4.1e-21 74.6 5.6 7.5e-21 73.7 5.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF45734.1 - 0.09 12.7 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain DFRP_C PF16543.5 OWF45734.1 - 4.2 7.9 14.9 0.42 11.1 4.6 2.6 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 cNMP_binding PF00027.29 OWF45735.1 - 8.8e-22 77.0 2.1 3e-13 49.7 0.4 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain SapB_1 PF05184.15 OWF45735.1 - 0.014 15.4 0.1 0.063 13.3 0.1 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 FAINT PF04385.15 OWF45735.1 - 0.026 14.6 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function, DUF529 7tm_2 PF00002.24 OWF45736.1 - 4.2e-45 154.0 22.9 6.6e-45 153.3 22.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TIG PF01833.24 OWF45736.1 - 3.9e-23 81.3 30.4 5e-09 36.1 5.6 6.3 6 0 0 6 6 6 4 IPT/TIG domain GPS PF01825.21 OWF45736.1 - 5e-15 55.7 5.7 1.9e-14 53.9 5.7 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PSI PF01437.25 OWF45736.1 - 1.6e-06 28.5 32.6 0.00083 19.8 3.4 3.9 3 0 0 3 3 3 2 Plexin repeat TIG_2 PF18020.1 OWF45736.1 - 6.7e-05 23.4 0.4 0.00027 21.5 0.4 2.1 1 0 0 1 1 1 1 TIG domain found in plexin GAIN PF16489.5 OWF45736.1 - 0.00078 18.9 1.7 0.0014 18.1 1.7 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain SBBP PF06739.11 OWF45736.1 - 0.014 15.4 0.1 1.4 9.0 0.1 3.1 2 0 0 2 2 2 0 Beta-propeller repeat DUF4992 PF16383.5 OWF45736.1 - 0.15 11.6 0.7 0.8 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function TIG_plexin PF17960.1 OWF45736.1 - 0.15 12.1 1.4 0.89 9.6 0.1 2.9 3 0 0 3 3 3 0 TIG domain DUF483 PF04467.12 OWF45736.1 - 0.28 11.2 1.8 3.8 7.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF483) Herpes_LMP1 PF05297.11 OWF45737.1 - 0.6 9.3 2.9 0.85 8.7 2.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Lsm_C PF14894.6 OWF45738.1 - 1.7 8.5 11.0 1.4e+02 2.4 0.0 6.2 7 0 0 7 7 7 0 Lsm C-terminal DUF664 PF04978.12 OWF45739.1 - 0.0027 18.1 0.1 4.8 7.6 0.0 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF664) HTH_AsnC-type PF13404.6 OWF45739.1 - 0.0031 17.3 0.6 25 4.8 0.0 5.1 2 2 5 7 7 7 1 AsnC-type helix-turn-helix domain HTH_8 PF02954.19 OWF45739.1 - 0.0075 16.0 0.1 11 5.9 0.0 3.8 2 2 2 5 5 5 2 Bacterial regulatory protein, Fis family Pirin_C_2 PF17954.1 OWF45740.1 - 2.6e-05 24.3 1.1 6.4 7.0 0.1 4.0 1 1 3 4 4 4 2 Quercetinase C-terminal cupin domain DUF348 PF03990.14 OWF45740.1 - 0.00043 20.0 3.6 4.9 7.0 0.0 4.7 2 2 2 4 4 4 2 G5-linked-Ubiquitin-like domain DUF4402 PF14352.6 OWF45740.1 - 0.019 15.6 4.0 0.84 10.3 4.0 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) Vps36_ESCRT-II PF11605.8 OWF45740.1 - 0.056 13.6 0.1 27 5.0 0.0 3.1 1 1 1 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Tudor_FRX1 PF18336.1 OWF45740.1 - 0.093 12.7 9.7 26 4.8 0.2 5.8 1 1 5 6 6 6 0 Fragile X mental retardation Tudor domain CEL_III_C PF18054.1 OWF45740.1 - 0.1 12.7 4.1 0.57 10.2 3.0 2.0 1 1 1 2 2 2 0 CEL-III C-terminal DUF4672 PF15716.5 OWF45740.1 - 0.16 11.6 4.2 2.2 7.8 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4672) PA14 PF07691.12 OWF45740.1 - 0.38 10.6 3.9 26 4.6 3.9 2.9 1 1 0 1 1 1 0 PA14 domain GluRS_N PF18466.1 OWF45740.1 - 1.4 9.4 4.4 9.3 6.7 0.6 2.8 1 1 2 3 3 3 0 Glutamate--tRNA ligase N-terminal domain E1_FCCH PF16190.5 OWF45740.1 - 9.9 6.5 8.0 1e+03 0.0 7.9 3.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain MFS_1 PF07690.16 OWF45741.1 - 3.2e-36 125.0 35.2 2.8e-34 118.6 34.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF45741.1 - 7.2e-14 51.4 21.6 1.4e-12 47.2 20.5 2.4 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 OWF45741.1 - 0.012 14.5 28.8 0.14 11.0 10.5 4.5 3 2 1 4 4 4 0 Sugar (and other) transporter ETX_MTX2 PF03318.13 OWF45742.1 - 1.5e-08 34.7 6.1 2e-08 34.3 6.1 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 OMP_b-brl_3 PF14905.6 OWF45742.1 - 0.00042 19.4 1.0 0.00051 19.1 1.0 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family SusF_SusE PF16411.5 OWF45742.1 - 0.049 14.1 1.1 0.083 13.4 0.2 2.1 1 1 1 2 2 2 0 Outer membrane protein SusF_SusE DUF2048 PF09752.9 OWF45742.1 - 0.094 11.8 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 CS PF04969.16 OWF45743.1 - 0.00034 21.6 1.5 0.00044 21.2 0.2 1.8 2 0 0 2 2 2 1 CS domain MBT PF02820.18 OWF45744.1 - 6.3e-81 266.7 4.8 6.8e-27 93.6 0.8 3.5 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 OWF45744.1 - 2.1e-27 94.9 25.1 5e-14 52.2 7.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2HC type SAM_1 PF00536.30 OWF45744.1 - 1.6e-14 54.1 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF45744.1 - 2.9e-07 30.5 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IBR PF01485.21 OWF45744.1 - 4.7 7.5 9.8 1.3 9.3 0.1 3.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain PCMT PF01135.19 OWF45745.1 - 3.6e-21 75.9 0.0 6.9e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 OWF45745.1 - 1.7e-06 28.3 1.2 0.0028 18.0 0.1 2.8 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 OWF45745.1 - 2.8e-06 27.0 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 GCD14 PF08704.10 OWF45745.1 - 0.0018 18.0 1.6 0.0042 16.8 0.0 2.1 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 OWF45745.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 OWF45745.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin zf-C2HC PF01530.18 OWF45746.1 - 5.9e-91 298.2 103.8 1.3e-15 57.3 7.4 8.0 8 0 0 8 8 8 7 Zinc finger, C2HC type MYT1 PF08474.11 OWF45746.1 - 0.011 15.7 3.5 0.054 13.4 3.5 2.3 1 1 0 1 1 1 0 Myelin transcription factor 1 ATG16 PF08614.11 OWF45746.1 - 0.066 13.4 22.3 0.04 14.1 6.3 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) ImpA_N PF06812.12 OWF45746.1 - 0.1 12.7 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system TMF_DNA_bd PF12329.8 OWF45746.1 - 0.45 10.6 14.7 0.13 12.3 10.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BRE1 PF08647.11 OWF45746.1 - 0.61 10.2 10.6 4.4 7.4 7.5 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 OWF45746.1 - 0.8 9.5 10.1 3.3 7.6 0.2 2.7 1 1 1 2 2 2 0 Septum formation initiator HalX PF08663.10 OWF45746.1 - 1.1 9.7 4.2 1.2 9.5 2.3 2.1 1 1 0 1 1 1 0 HalX domain YabA PF06156.13 OWF45746.1 - 2.6 8.7 6.7 0.92 10.2 2.9 2.3 2 0 0 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 OWF45746.1 - 8.2 6.9 9.8 3.1 8.3 4.7 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Laps PF10169.9 OWF45746.1 - 8.7 6.9 8.8 1.2 9.8 2.8 2.6 2 0 0 2 2 2 0 Learning-associated protein WD40 PF00400.32 OWF45747.1 - 5.3e-16 58.7 13.8 8.8e-06 26.4 0.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat DUF5061 PF16587.5 OWF45747.1 - 0.11 12.6 0.1 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 17 kDa common-antigen outer membrane protein TPR_1 PF00515.28 OWF45748.1 - 2.4e-11 43.0 0.0 0.0016 18.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF45748.1 - 6.1e-11 41.6 0.0 0.016 15.3 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF45748.1 - 2e-08 34.6 0.0 0.00024 21.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF45748.1 - 4.3e-07 29.5 0.0 0.0055 16.4 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 OWF45748.1 - 1.2e-06 28.7 0.0 0.001 19.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF45748.1 - 3.3e-05 23.9 0.0 0.001 19.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF45748.1 - 3.4e-05 24.2 0.1 1 10.1 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 OWF45748.1 - 4.1e-05 23.1 0.0 0.00015 21.3 0.1 1.9 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_7 PF13176.6 OWF45748.1 - 5.1e-05 23.0 0.0 0.81 9.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF45748.1 - 0.00013 21.9 0.3 1.1 9.7 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF45748.1 - 0.00061 20.0 0.0 0.26 11.6 0.0 3.3 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OWF45748.1 - 0.00073 19.6 0.0 0.03 14.4 0.0 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF45748.1 - 0.034 15.0 0.0 87 4.4 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF45748.1 - 0.099 13.3 0.0 2.9 8.6 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 OWF45748.1 - 0.13 12.6 0.2 22 5.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5588 PF17826.1 OWF45749.1 - 3.8e-24 85.3 4.4 8.8e-24 84.1 1.4 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF5588) TPR_16 PF13432.6 OWF45749.1 - 0.011 16.4 3.7 0.88 10.3 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat HGD-D PF06050.13 OWF45749.1 - 0.052 13.3 0.4 8.1 6.1 0.4 2.1 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component TPR_2 PF07719.17 OWF45749.1 - 0.052 13.7 0.7 0.052 13.7 0.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF45749.1 - 0.08 13.5 4.0 2.1 8.9 1.7 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF45749.1 - 0.13 12.1 3.6 0.19 11.6 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF45749.1 - 0.36 11.1 3.7 4.7 7.6 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 OWF45750.1 - 3.6e-37 127.0 0.0 5.4e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OWF45750.1 - 1.9e-14 53.6 0.0 2.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OWF45750.1 - 8.5e-13 47.9 0.1 1.4e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin PF00085.20 OWF45751.1 - 4.3e-28 97.3 0.6 5.3e-28 97.0 0.6 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OWF45751.1 - 2.2e-06 28.0 0.1 7.7e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OWF45751.1 - 2.8e-05 23.9 0.1 2.9e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OWF45751.1 - 0.00014 21.8 0.1 0.00016 21.6 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OWF45751.1 - 0.00048 20.4 0.0 0.0013 19.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OWF45751.1 - 0.00067 19.4 0.2 0.00075 19.2 0.2 1.1 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 OWF45751.1 - 0.0008 18.8 0.0 0.00098 18.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OWF45751.1 - 0.024 14.8 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 OWF45751.1 - 0.068 12.1 0.0 0.076 11.9 0.0 1.0 1 0 0 1 1 1 0 Phosducin Rhodanese PF00581.20 OWF45752.1 - 1.4e-08 35.2 0.0 2.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain AAA_22 PF13401.6 OWF45752.1 - 0.023 15.0 0.1 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2385 PF09539.10 OWF45752.1 - 0.12 12.9 0.1 0.29 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Y_phosphatase PF00102.27 OWF45753.1 - 1.9e-116 387.6 8.2 4.5e-76 255.5 3.1 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF45753.1 - 0.0058 16.4 0.5 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF45753.1 - 0.007 16.5 0.0 0.03 14.4 0.0 2.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF45753.1 - 0.026 14.5 0.3 0.073 13.0 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Ribosomal_S7e PF01251.18 OWF45754.1 - 1.6e-90 301.8 5.9 1.8e-90 301.7 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RNase_H PF00075.24 OWF45755.1 - 1.9e-40 138.3 0.5 8e-40 136.3 0.0 2.0 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 OWF45755.1 - 2.4e-21 75.8 0.7 5.1e-21 74.7 0.7 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 OWF45755.1 - 0.00012 21.9 0.2 0.00049 19.9 0.1 2.3 2 1 0 2 2 2 1 Reverse transcriptase-like Collagen PF01391.18 OWF45756.1 - 1.3e-22 79.3 54.1 2.5e-09 36.8 17.8 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) RabGAP-TBC PF00566.18 OWF45757.1 - 8.2e-57 192.3 0.2 8.2e-57 192.3 0.2 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PH PF00169.29 OWF45757.1 - 1.6e-06 28.6 0.0 4.4e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 PH domain FPP PF05911.11 OWF45757.1 - 2.6e-05 22.6 10.8 2.6e-05 22.6 10.8 1.7 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 OWF45757.1 - 1 8.6 10.5 5.3 6.3 3.9 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) IL12 PF03039.14 OWF45757.1 - 1.1 8.6 8.2 0.32 10.3 0.3 2.4 2 1 0 2 2 2 0 Interleukin-12 alpha subunit Sec20 PF03908.13 OWF45757.1 - 1.4 8.9 4.7 0.86 9.6 0.6 2.6 2 0 0 2 2 2 0 Sec20 GAT PF03127.14 OWF45757.1 - 4.7 7.6 10.3 11 6.4 1.7 3.9 3 0 0 3 3 3 0 GAT domain Poxvirus PF06227.12 OWF45758.1 - 2e-06 27.7 1.7 1.5 8.6 0.0 3.6 3 0 0 3 3 3 3 dsDNA Poxvirus MSG PF02349.15 OWF45758.1 - 0.009 16.2 0.8 41 4.5 0.0 3.3 3 0 0 3 3 3 1 Major surface glycoprotein zf-C5HC2 PF02928.16 OWF45758.1 - 5.5 7.5 8.6 26 5.3 0.2 3.4 3 0 0 3 3 3 0 C5HC2 zinc finger AGA2 PF17366.2 OWF45758.1 - 9.1 6.1 6.4 4.2 7.2 0.2 2.9 3 0 0 3 3 3 0 A-agglutinin-binding subunit Aga2 DUF5561 PF17716.1 OWF45760.1 - 3.5e-65 219.8 0.2 4.6e-65 219.4 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5561) JmjC PF02373.22 OWF45761.1 - 3.9e-43 146.5 0.2 3.9e-43 146.5 0.2 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 OWF45761.1 - 4e-31 107.4 9.3 4e-31 107.4 9.3 2.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 OWF45761.1 - 4.2e-22 77.5 5.8 1.1e-11 44.2 2.5 2.7 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain zf-HC5HC2H PF13771.6 OWF45761.1 - 5.2e-16 58.7 4.4 5.2e-16 58.7 4.4 4.0 3 1 1 4 4 4 1 PHD-like zinc-binding domain JmjN PF02375.17 OWF45761.1 - 1.6e-12 47.1 0.1 3.4e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.6 OWF45761.1 - 9.6e-12 44.3 5.7 9.6e-12 44.3 5.7 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 OWF45761.1 - 5.8e-05 22.9 18.2 0.00038 20.3 7.0 3.0 2 0 0 2 2 2 2 PHD-finger TUDOR_5 PF18359.1 OWF45761.1 - 0.0012 18.5 0.6 0.0057 16.3 0.6 2.2 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 RPEL PF02755.15 OWF45762.1 - 1.3e-26 91.4 13.5 2.8e-06 26.8 0.0 4.5 4 0 0 4 4 4 4 RPEL repeat DUF2737 PF10930.8 OWF45762.1 - 0.081 12.5 5.5 3.2 7.4 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2737) PDZ_6 PF17820.1 OWF45763.1 - 1.4e-18 66.5 0.7 2.9e-12 46.2 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OWF45763.1 - 6.9e-18 64.8 2.0 2.3e-09 37.5 0.1 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 OWF45763.1 - 1.5e-12 47.7 1.5 1.1e-08 35.3 0.0 2.5 1 1 1 2 2 2 2 PDZ domain Asp_Arg_Hydrox PF05118.15 OWF45763.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Ketoacyl-synt_2 PF13723.6 OWF45763.1 - 0.38 10.4 2.4 12 5.4 0.0 2.4 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Pkinase_Tyr PF07714.17 OWF45764.1 - 2e-96 322.2 0.0 2.7e-96 321.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF45764.1 - 3.7e-47 160.9 0.0 5.4e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF45764.1 - 1.3e-23 82.9 0.0 3.3e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 OWF45764.1 - 2e-16 59.3 0.1 5.1e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF45764.1 - 4.8e-12 45.5 0.0 2.4e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OWF45764.1 - 8.7e-08 31.7 0.0 1.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 OWF45764.1 - 0.00023 20.2 0.0 0.00043 19.4 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF45764.1 - 0.017 15.0 0.0 0.11 12.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIC1 PF07064.13 OWF45765.1 - 5.7e-86 288.0 0.0 1.3e-85 286.8 0.0 1.7 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 OWF45765.1 - 0.00014 22.1 0.1 0.11 12.8 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Tctex-1 PF03645.13 OWF45766.1 - 2.7e-24 85.4 0.0 3.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF3945 PF13101.6 OWF45766.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Drf_FH1 PF06346.12 OWF45767.1 - 7.8e-07 28.9 3.9 0.0019 18.0 1.0 2.1 1 1 1 2 2 2 2 Formin Homology Region 1 CREPT PF16566.5 OWF45767.1 - 0.031 14.5 23.3 7.2e+02 0.3 0.0 6.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PX PF00787.24 OWF45768.1 - 1.3e-23 83.1 2.3 3.1e-23 81.9 2.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OWF45768.1 - 3.8e-10 39.7 10.4 2.8e-09 36.9 10.4 2.1 1 1 0 1 1 1 1 Vps5 C terminal like MbeD_MobD PF04899.12 OWF45768.1 - 0.023 14.8 1.0 0.4 10.8 0.2 3.0 2 0 0 2 2 2 0 MbeD/MobD like Cep57_MT_bd PF06657.13 OWF45768.1 - 0.11 13.0 5.4 1.7 9.2 0.4 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SOSSC PF15925.5 OWF45769.1 - 4.2e-20 72.9 0.2 7.5e-20 72.1 0.2 1.4 1 1 0 1 1 1 1 SOSS complex subunit C Flg_bbr_C PF06429.13 OWF45769.1 - 0.0032 17.6 0.4 0.0056 16.8 0.4 1.4 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal DUF4813 PF16072.5 OWF45769.1 - 0.0039 16.9 6.1 0.0048 16.6 6.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) Chorion_3 PF05387.11 OWF45769.1 - 0.47 10.0 8.4 0.59 9.7 8.4 1.1 1 0 0 1 1 1 0 Chorion family 3 Reeler PF02014.16 OWF45770.1 - 2e-26 93.3 0.0 4.1e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 OWF45770.1 - 1.4e-14 54.4 1.1 3.1e-14 53.3 1.1 1.6 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 OWF45770.1 - 1.7e-10 41.2 3.0 4.5e-10 39.8 3.0 1.8 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 OWF45770.1 - 0.011 15.6 10.3 0.41 10.6 1.8 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like DUF4079 PF13301.6 OWF45770.1 - 0.015 15.5 1.8 0.054 13.6 1.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF4064 PF13273.6 OWF45770.1 - 0.016 15.5 3.6 0.82 10.0 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF3273 PF11677.8 OWF45770.1 - 0.27 10.5 4.9 0.048 13.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3273) Ni_hydr_CYTB PF01292.20 OWF45770.1 - 2.6 7.6 11.6 29 4.2 11.2 2.7 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 F5_F8_type_C PF00754.25 OWF45771.1 - 8.4e-20 71.2 0.0 1.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain PAN_1 PF00024.26 OWF45771.1 - 8.5e-06 25.6 1.9 1.9e-05 24.5 1.9 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF45771.1 - 8.6e-05 22.4 0.5 0.00035 20.4 0.5 2.1 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 OWF45771.1 - 0.019 15.0 2.4 0.065 13.4 2.4 1.9 1 1 0 1 1 1 0 PAN-like domain PAN_3 PF08277.12 OWF45771.1 - 0.023 14.5 0.6 0.023 14.5 0.6 2.2 3 0 0 3 3 3 0 PAN-like domain F5_F8_type_C PF00754.25 OWF45772.1 - 7.6e-17 61.6 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain PAN_1 PF00024.26 OWF45772.1 - 2.1e-05 24.4 0.2 5.1e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF45772.1 - 7.5e-05 22.6 0.3 0.00022 21.0 0.3 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 OWF45772.1 - 0.0059 16.7 0.2 0.018 15.2 0.2 1.8 1 0 0 1 1 1 1 PAN-like domain PAN_3 PF08277.12 OWF45772.1 - 0.091 12.6 2.7 0.1 12.4 0.3 2.3 2 0 0 2 2 2 0 PAN-like domain F5_F8_type_C PF00754.25 OWF45774.1 - 9.2e-22 77.5 0.1 1.2e-21 77.1 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain PAN_4 PF14295.6 OWF45774.1 - 0.0026 17.6 0.2 0.0083 16.0 0.2 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 OWF45774.1 - 0.0046 16.9 0.1 0.0094 15.9 0.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 OWF45774.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain HDOD PF08668.12 OWF45775.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 HDOD domain TPR_MLP1_2 PF07926.12 OWF45775.1 - 0.024 14.7 7.8 0.086 12.9 5.9 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.13 OWF45775.1 - 0.026 14.6 3.7 0.026 14.6 3.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4164 PF13747.6 OWF45775.1 - 0.032 14.5 9.1 0.7 10.2 0.4 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) Sec66 PF09802.9 OWF45775.1 - 0.049 13.2 0.8 5.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 FtsK_SpoIIIE_N PF12538.8 OWF45775.1 - 0.066 13.4 2.0 0.13 12.5 2.0 1.5 1 0 0 1 1 1 0 DNA transporter Shugoshin_N PF07558.11 OWF45775.1 - 0.075 12.9 5.5 2.9 7.8 0.2 3.6 3 2 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Spectrin PF00435.21 OWF45775.1 - 0.22 12.0 7.5 0.42 11.1 4.8 2.4 1 1 1 2 2 2 0 Spectrin repeat RWD PF05773.22 OWF45776.1 - 7.3e-22 77.8 0.1 1.6e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 OWF45776.1 - 1.3e-18 67.0 16.6 2.6e-12 46.8 1.5 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OWF45776.1 - 0.0024 18.2 5.1 0.0024 18.2 5.1 3.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF45776.1 - 0.0028 17.7 5.7 0.0028 17.7 5.7 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF45776.1 - 0.0028 17.6 8.1 0.0028 17.6 8.1 4.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF45776.1 - 0.011 15.6 4.7 0.011 15.6 4.7 4.4 3 2 2 5 5 5 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.6 OWF45776.1 - 0.15 12.0 11.9 0.12 12.3 7.2 3.3 3 0 0 3 3 3 0 YhfH-like protein OTT_1508_deam PF14441.6 OWF45776.1 - 0.42 10.7 11.0 1.5 8.9 3.0 2.9 2 0 0 2 2 2 0 OTT_1508-like deaminase zf-RING_11 PF17123.5 OWF45776.1 - 2 8.2 9.2 6 6.7 7.2 2.9 2 0 0 2 2 2 0 RING-like zinc finger CARD PF00619.21 OWF45777.1 - 6.6e-11 42.1 0.5 0.00063 19.7 0.1 3.1 2 0 0 2 2 2 2 Caspase recruitment domain CARD_2 PF16739.5 OWF45777.1 - 1.8e-05 24.6 0.1 0.0018 18.2 0.0 3.2 2 1 0 2 2 2 1 Caspase recruitment domain Death PF00531.22 OWF45777.1 - 0.0002 21.5 2.5 0.0033 17.5 0.1 3.1 3 0 0 3 3 3 1 Death domain DUF4407 PF14362.6 OWF45777.1 - 8.9 5.6 7.4 20 4.4 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Anoctamin PF04547.12 OWF45778.1 - 4.2e-118 395.1 8.3 7.9e-118 394.1 8.3 1.5 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OWF45778.1 - 2e-24 86.6 17.3 2.2e-22 79.9 3.8 3.0 3 1 0 3 3 3 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Anoctamin PF04547.12 OWF45779.1 - 6.7e-123 410.8 11.9 1e-122 410.2 11.9 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OWF45779.1 - 1.1e-15 58.1 1.0 1.1e-15 58.1 1.0 3.7 4 1 0 4 4 4 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.9 OWF45779.1 - 0.084 11.6 2.0 0.82 8.4 2.0 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase_Tyr PF07714.17 OWF45780.1 - 1e-87 293.7 0.2 1.7e-87 293.0 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF45780.1 - 2.9e-42 144.9 0.0 5.7e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF45780.1 - 1.1e-19 70.2 0.5 3.5e-19 68.7 0.5 1.9 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 OWF45780.1 - 9.6e-13 48.6 1.0 3.1e-12 46.9 1.0 1.9 2 0 0 2 2 1 1 PH domain SH3_1 PF00018.28 OWF45780.1 - 3.5e-11 42.5 0.1 7.9e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF45780.1 - 1.7e-09 37.4 0.1 4.4e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain BTK PF00779.19 OWF45780.1 - 4.5e-09 36.0 1.1 1.1e-08 34.7 1.1 1.8 1 0 0 1 1 1 1 BTK motif SH3_2 PF07653.17 OWF45780.1 - 2.1e-05 24.1 0.1 9.2e-05 22.0 0.1 2.2 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 OWF45780.1 - 0.0012 19.2 0.0 0.0046 17.3 0.0 2.0 1 0 0 1 1 1 1 Helically-extended SH3 domain Haspin_kinase PF12330.8 OWF45780.1 - 0.042 12.8 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OWF45780.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH_11 PF15413.6 OWF45780.1 - 0.41 11.1 4.8 0.24 11.8 2.3 2.0 2 0 0 2 2 1 0 Pleckstrin homology domain Cuticle_1 PF08140.11 OWF45780.1 - 0.42 10.7 1.1 51 4.0 0.0 3.7 3 1 1 4 4 4 0 Crustacean cuticle protein repeat DUF1876 PF08962.11 OWF45780.1 - 4 7.5 7.7 12 5.9 0.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1876) LZ_Tnp_IS481 PF13011.6 OWF45780.1 - 6.4 7.4 13.1 22 5.7 1.3 4.6 2 2 3 5 5 5 0 leucine-zipper of insertion element IS481 Med7 PF05983.11 OWF45781.1 - 3.4e-51 174.1 10.9 9.2e-50 169.4 10.9 2.0 1 1 0 1 1 1 1 MED7 protein Ank_5 PF13857.6 OWF45782.1 - 2.7e-05 24.3 0.0 6.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF45782.1 - 0.00036 21.1 0.0 0.00074 20.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF45782.1 - 0.00066 20.2 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF45782.1 - 0.0012 19.2 0.0 0.0034 17.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 OWF45782.1 - 0.0013 19.1 0.0 0.0042 17.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat PTEN_C2 PF10409.9 OWF45783.1 - 1.2e-18 67.1 0.3 2.1e-18 66.4 0.3 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OWF45783.1 - 1.5e-05 24.8 0.0 5.5e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF45783.1 - 0.00068 19.8 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate ResB PF05140.14 OWF45783.1 - 0.0031 16.3 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 ResB-like family Y_phosphatase PF00102.27 OWF45783.1 - 0.0051 16.4 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF45783.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family IF3_C PF00707.22 OWF45784.1 - 0.00011 22.1 0.7 0.00011 22.1 0.7 2.3 2 1 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain FtsK_alpha PF17854.1 OWF45784.1 - 0.0072 16.5 0.8 1.4 9.1 0.0 3.1 3 0 0 3 3 3 1 FtsK alpha domain Fip1 PF05182.13 OWF45785.1 - 2.9e-22 77.9 2.6 6.3e-22 76.8 2.6 1.6 1 0 0 1 1 1 1 Fip1 motif Thioredoxin PF00085.20 OWF45786.1 - 2.3e-07 30.7 0.2 4.5e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 OWF45786.1 - 3.3e-06 26.2 0.3 4.2e-06 25.9 0.3 1.1 1 0 0 1 1 1 1 Phosducin DB_JBP1 PF18526.1 OWF45786.1 - 0.038 13.9 1.3 0.051 13.5 1.3 1.1 1 0 0 1 1 1 0 Thymine dioxygenase JBP1 DNA-binding domain KaiB PF07689.12 OWF45786.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 KaiB domain Tat PF00539.18 OWF45787.1 - 0.025 14.7 0.4 0.059 13.5 0.4 1.6 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) FH2 PF02181.23 OWF45788.1 - 7e-85 285.4 1.5 1.9e-84 284.0 1.5 1.8 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OWF45788.1 - 3.4e-28 98.6 3.7 3.4e-28 98.6 3.7 2.8 2 1 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OWF45788.1 - 1.5e-15 57.3 2.0 2e-15 56.8 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain JUPITER PF17054.5 OWF45789.1 - 3.2e-10 40.0 8.0 4.3e-05 23.2 0.2 2.3 1 1 1 2 2 2 2 Microtubule-Associated protein Jupiter Myb_DNA-bind_7 PF15963.5 OWF45790.1 - 0.0014 18.4 0.1 0.004 17.0 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like PTS_EIIA_1 PF00358.20 OWF45790.1 - 0.043 13.6 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Myb_DNA-binding PF00249.31 OWF45790.1 - 0.065 13.4 0.0 0.38 11.0 0.0 2.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain RMI1_N PF08585.12 OWF45791.1 - 1e-25 90.8 0.0 2.7e-23 82.9 0.1 4.6 3 2 1 4 4 4 2 RecQ mediated genome instability protein SMN PF06003.12 OWF45791.1 - 4.1e-10 39.4 0.0 4.1e-10 39.4 0.0 3.7 2 1 0 3 3 3 1 Survival motor neuron protein (SMN) UBA PF00627.31 OWF45791.1 - 6.9e-08 32.2 0.1 1.9e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TUDOR PF00567.24 OWF45791.1 - 5e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Tudor domain CUE PF02845.16 OWF45791.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 CUE domain FH2 PF02181.23 OWF45792.1 - 1.1e-97 327.6 17.7 1.1e-97 327.6 17.7 3.0 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OWF45792.1 - 1.3e-55 188.0 1.1 3.6e-55 186.6 0.1 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OWF45792.1 - 3.6e-39 134.3 0.6 3.6e-39 134.3 0.6 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_DAD PF06345.11 OWF45792.1 - 0.044 13.8 0.1 0.044 13.8 0.1 2.1 2 0 0 2 2 2 0 DRF Autoregulatory Domain DUF3726 PF12525.8 OWF45792.1 - 0.081 13.0 0.0 5.8 7.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) IMS PF00817.20 OWF45792.1 - 0.88 9.6 2.8 6.1 6.8 0.8 3.0 2 1 0 2 2 2 0 impB/mucB/samB family Keratin_B2 PF01500.17 OWF45793.1 - 0.011 15.7 1.4 0.013 15.5 1.4 1.1 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein VERL PF11386.8 OWF45793.1 - 0.14 12.4 3.7 2.1 8.6 0.1 3.2 1 1 2 3 3 3 0 Vitelline envelope receptor for lysin HSP70 PF00012.20 OWF45794.1 - 3.7e-09 35.4 0.0 1.6e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 OWF45794.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.13 OWF45794.1 - 0.015 14.1 0.1 1 8.1 0.0 2.5 2 1 0 2 2 2 0 MreB/Mbl protein p450 PF00067.22 OWF45795.1 - 1.6e-114 383.2 0.0 1.8e-114 383.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S78_2 PF14550.6 OWF45795.1 - 0.00077 19.5 0.1 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Putative phage serine protease XkdF DUF4455 PF14643.6 OWF45795.1 - 0.025 13.2 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) GST_C PF00043.25 OWF45796.1 - 2.4e-26 91.8 0.0 3.1e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF45796.1 - 9.2e-16 57.9 0.0 5.7e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF45796.1 - 4.3e-14 52.3 0.0 1.1e-05 25.4 0.0 3.3 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF45796.1 - 1.2e-13 51.2 0.0 4.8e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF45796.1 - 1.6e-12 47.6 0.0 3.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF45796.1 - 2.2e-09 37.5 0.0 4.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OWF45796.1 - 5.5e-06 26.1 0.1 0.17 11.7 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 OWF45796.1 - 0.003 17.4 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin 2, C terminal domain DUF3311 PF11755.8 OWF45796.1 - 0.054 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) UME PF08064.13 OWF45796.1 - 0.15 12.0 0.1 2 8.4 0.0 2.5 2 1 0 2 2 2 0 UME (NUC010) domain zf-Tim10_DDP PF02953.15 OWF45797.1 - 4.4e-09 35.9 3.1 7e-09 35.2 3.1 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger LRRC37AB_C PF14914.6 OWF45797.1 - 0.0041 17.0 0.4 0.0048 16.8 0.4 1.1 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain CDP-OH_P_transf PF01066.21 OWF45798.1 - 0.0008 20.1 4.3 0.0024 18.6 0.0 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF2189 PF09955.9 OWF45798.1 - 0.094 13.0 9.5 2.5 8.3 4.0 2.9 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2189) Lipase3_N PF03893.16 OWF45798.1 - 0.39 10.8 3.6 19 5.3 0.2 2.8 3 0 0 3 3 3 0 Lipase 3 N-terminal region DUF3919 PF13057.6 OWF45799.1 - 0.042 13.4 0.0 12 5.4 0.0 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3919) Josephin PF02099.17 OWF45799.1 - 0.083 13.0 0.1 44 4.1 0.0 2.9 1 1 1 3 3 3 0 Josephin CDP-OH_P_transf PF01066.21 OWF45800.1 - 0.24 12.2 0.0 0.24 12.2 0.0 3.0 3 1 0 3 3 3 0 CDP-alcohol phosphatidyltransferase STELLO PF03385.17 OWF45801.1 - 6.6e-11 41.6 0.0 9.7e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases Galactosyl_T PF01762.21 OWF45801.1 - 7.2e-07 29.2 0.2 1.6e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Galactosyltransferase TIR_2 PF13676.6 OWF45802.1 - 9.4e-18 64.9 0.0 2.2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF45802.1 - 0.026 14.3 0.0 0.09 12.6 0.0 1.9 1 0 0 1 1 1 0 TIR domain Ish1 PF10281.9 OWF45802.1 - 1.6 9.1 3.9 4.9 7.5 3.9 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein RRM_1 PF00076.22 OWF45803.1 - 0.045 13.6 0.1 3 7.7 0.0 3.5 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1d PF00750.19 OWF45804.1 - 2.8e-137 457.3 0.0 3.9e-137 456.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OWF45804.1 - 1.8e-30 105.5 0.3 5.1e-30 104.1 0.0 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OWF45804.1 - 1.1e-17 64.4 0.1 4.8e-17 62.3 0.1 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Retrotran_gag_2 PF14223.6 OWF45804.1 - 0.0068 16.1 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DivIC PF04977.15 OWF45804.1 - 0.032 14.0 5.5 0.78 9.6 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator HATPase_c_2 PF13581.6 OWF45804.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Spc7 PF08317.11 OWF45804.1 - 0.098 11.5 2.5 0.46 9.3 2.7 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 OWF45804.1 - 0.1 12.6 4.1 0.56 10.2 1.6 2.4 2 0 0 2 2 2 0 FlxA-like protein SKA2 PF16740.5 OWF45804.1 - 0.15 11.9 0.9 24 4.8 0.0 2.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Mto2_bdg PF12808.7 OWF45804.1 - 0.2 12.0 2.3 0.43 10.9 1.8 1.9 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CCDC92 PF14916.6 OWF45804.1 - 0.34 10.7 2.1 0.89 9.4 2.1 1.7 1 1 0 1 1 1 0 Coiled-coil domain of unknown function DUF5082 PF16888.5 OWF45804.1 - 0.95 9.8 3.9 7.2 6.9 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 OWF45804.1 - 1.3 9.1 5.0 12 6.1 0.9 2.7 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.8 OWF45804.1 - 4.2 7.4 8.4 5.1 7.2 5.4 2.3 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 OWF45804.1 - 5.5 7.5 8.5 37 4.8 5.9 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Lamprin PF06403.11 OWF45805.1 - 5 7.1 8.6 1.4 8.9 4.9 2.0 1 1 1 2 2 2 0 Lamprin DUF4728 PF15860.5 OWF45808.1 - 1.3e-08 35.4 6.5 1.3e-08 35.4 6.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4728) LRR_8 PF13855.6 OWF45809.1 - 1.8e-52 174.9 45.8 3.1e-12 46.1 5.8 7.5 5 2 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OWF45809.1 - 3.1e-21 75.1 53.7 2.6e-05 24.5 2.1 9.9 5 2 7 12 12 12 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF45809.1 - 2.3e-15 56.7 3.9 1e-05 25.5 0.0 4.4 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF45809.1 - 2.8e-07 30.2 19.0 0.006 16.1 1.8 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 OWF45809.1 - 0.0011 19.3 38.1 27 5.8 0.2 13.2 12 3 0 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF45809.1 - 0.0083 16.1 40.2 0.63 10.2 0.1 11.2 14 0 0 14 14 14 3 Leucine Rich repeat DUF2682 PF10909.8 OWF45809.1 - 0.12 12.9 4.6 1.3 9.5 0.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2682) PAP2 PF01569.21 OWF45810.1 - 4.1e-26 91.4 0.7 4.1e-26 91.4 0.7 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OWF45810.1 - 0.00029 20.6 0.9 0.001 18.8 0.9 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OWF45810.1 - 0.049 14.2 0.1 0.049 14.2 0.1 2.4 3 1 0 3 3 3 0 PAP2 superfamily C-terminal PhyH PF05721.13 OWF45811.1 - 1.8e-29 103.5 0.0 2.4e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 OWF45811.1 - 0.093 13.6 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 OWF45812.1 - 2.6e-29 103.0 0.0 7.1e-29 101.6 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OWF45812.1 - 0.0026 18.1 0.0 0.0087 16.5 0.0 1.9 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase RCDG1 PF15725.5 OWF45812.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein 2OG-FeII_Oxy_3 PF13640.6 OWF45812.1 - 0.041 14.8 0.0 0.11 13.4 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Usp PF00582.26 OWF45815.1 - 3.5e-17 63.2 0.1 4e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 OWF45816.1 - 3.2e-26 92.5 0.0 5.8e-26 91.7 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family HEPN_Apea PF18739.1 OWF45816.1 - 0.066 13.7 0.1 0.091 13.2 0.1 1.2 1 0 0 1 1 1 0 Apea-like HEPN Pox_polyA_pol_N PF12630.7 OWF45816.1 - 0.1 13.0 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Usp PF00582.26 OWF45817.1 - 5.9e-28 98.2 0.0 7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family HLH PF00010.26 OWF45818.1 - 4.5e-13 48.9 3.5 8e-13 48.1 3.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3958 PF13125.6 OWF45818.1 - 0.79 10.0 4.9 0.44 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) CLCA PF08434.11 OWF45819.1 - 3.9e-57 193.6 0.3 7e-57 192.8 0.3 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 OWF45819.1 - 3.9e-19 69.6 0.7 8e-19 68.6 0.7 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF45819.1 - 4.6e-15 56.2 0.3 1.2e-14 54.8 0.3 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF45819.1 - 1.5e-06 27.8 0.2 4.4e-06 26.3 0.2 1.7 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 OWF45819.1 - 5.6e-05 22.4 0.2 0.0002 20.6 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1194) TraB PF01963.17 OWF45820.1 - 6.6e-29 101.6 0.1 1.1e-28 100.9 0.1 1.2 1 0 0 1 1 1 1 TraB family HIT PF01230.23 OWF45822.1 - 0.034 14.9 0.2 0.088 13.6 0.2 1.6 1 0 0 1 1 1 0 HIT domain SET PF00856.28 OWF45823.1 - 8.7e-22 78.3 0.1 3.4e-21 76.3 0.1 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 OWF45823.1 - 1.1e-17 64.6 9.1 1.1e-17 64.6 9.1 2.4 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 OWF45823.1 - 4.1e-15 55.4 4.1 1.1e-14 54.1 4.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OWF45823.1 - 0.021 14.9 1.0 0.19 11.9 0.2 2.5 2 0 0 2 2 2 0 Chromo shadow domain Ig_3 PF13927.6 OWF45824.1 - 4.1e-08 33.7 1.4 0.047 14.3 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 OWF45824.1 - 0.00073 19.6 0.2 0.0042 17.1 0.2 2.3 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF45824.1 - 0.0012 18.9 1.5 0.068 13.3 0.0 2.9 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF45824.1 - 0.014 15.7 1.6 0.15 12.4 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin domain C2-set PF05790.15 OWF45824.1 - 1 9.6 3.6 5.2 7.3 0.0 3.3 3 1 1 4 4 4 0 Immunoglobulin C2-set domain Sulfotransfer_2 PF03567.14 OWF45825.1 - 2.4e-32 112.8 2.6 4.3e-32 112.0 2.6 1.4 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_M13 PF01431.21 OWF45826.1 - 1.8e-60 204.1 0.0 2.5e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 THAP PF05485.12 OWF45826.1 - 6.4e-13 49.5 0.4 6.4e-13 49.5 0.4 2.1 2 1 1 3 3 3 1 THAP domain XPG_I_2 PF12813.7 OWF45827.1 - 0.016 14.7 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 XPG domain containing XPG_I PF00867.18 OWF45827.1 - 0.017 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 XPG I-region 5_3_exonuc_N PF02739.16 OWF45827.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Methyltransf_25 PF13649.6 OWF45827.1 - 0.16 12.7 0.2 0.69 10.7 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain LPMO_10 PF03067.15 OWF45828.1 - 1e-15 58.9 1.4 1e-15 58.9 1.4 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Peptidase_M13_N PF05649.13 OWF45829.1 - 2.1e-109 366.7 1.1 3e-109 366.2 1.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF45829.1 - 4.6e-69 232.1 0.0 8.1e-69 231.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 MFS_1 PF07690.16 OWF45830.1 - 3.5e-19 68.9 28.3 8.1e-19 67.7 28.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Esterase PF00756.20 OWF45830.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase He_PIG PF05345.12 OWF45831.1 - 9.5e-16 57.7 0.0 69 3.7 0.0 10.9 11 0 0 11 11 11 11 Putative Ig domain DUF3949 PF13133.6 OWF45832.1 - 1.2e-06 28.9 0.0 1.5e+02 2.9 0.0 11.7 12 2 2 18 18 18 0 Protein of unknown function (DUF3949) MHC_I_C PF06623.11 OWF45832.1 - 0.0013 18.6 26.7 58 3.7 0.1 11.1 12 0 0 12 12 12 7 MHC_I C-terminus Calponin PF00402.18 OWF45832.1 - 0.032 13.9 28.8 1e+02 2.6 0.1 12.7 9 0 0 9 9 9 0 Calponin family repeat Sulfotransfer_1 PF00685.27 OWF45834.1 - 4.2e-13 49.4 0.5 1.3e-12 47.8 0.5 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF45834.1 - 2.5e-11 44.4 1.3 1.9e-10 41.5 1.3 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF45834.1 - 0.0011 18.9 2.3 0.0018 18.2 2.3 1.4 1 0 0 1 1 1 1 Sulfotransferase family Glyco_transf_10 PF00852.19 OWF45835.1 - 1.1e-43 149.1 3.5 1.8e-43 148.3 3.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF45835.1 - 7.7e-19 68.2 1.2 9.6e-18 64.7 0.0 2.7 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal zf_PR_Knuckle PF18445.1 OWF45835.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif zf-like PF04071.12 OWF45835.1 - 2.3 8.2 5.8 12 5.9 0.0 3.1 3 1 1 4 4 4 0 Cysteine-rich small domain Adeno_E3A PF05248.12 OWF45836.1 - 1.1 9.3 10.4 2.3 8.3 1.3 2.6 2 1 0 2 2 2 0 Adenovirus E3A VARLMGL PF14383.6 OWF45837.1 - 0.025 14.1 2.1 18 5.0 0.2 4.6 3 1 0 3 3 3 0 DUF761-associated sequence motif Colipase-like PF15083.6 OWF45837.1 - 1.2 9.3 6.8 11 6.2 0.3 2.8 3 1 0 3 3 3 0 Colipase-like Transglut_core PF01841.19 OWF45838.1 - 0.094 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily ATP-gua_Ptrans PF00217.19 OWF45839.1 - 3.9e-80 268.3 0.0 5.1e-80 267.9 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 OWF45839.1 - 1.3e-20 73.6 0.0 2.2e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Glyco_transf_7N PF13733.6 OWF45840.1 - 1.4e-54 183.3 0.0 2.3e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF45840.1 - 8.9e-30 102.2 0.4 2.5e-29 100.7 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF45840.1 - 0.063 12.7 0.1 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 7tm_1 PF00001.21 OWF45842.1 - 6.5e-48 163.3 18.5 9e-48 162.9 18.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF45842.1 - 1.6e-10 40.8 21.3 3e-10 39.9 21.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF45842.1 - 4.2e-10 39.4 18.6 6.2e-10 38.9 18.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF45842.1 - 1e-06 28.7 15.9 5.4e-06 26.4 15.9 2.0 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF45842.1 - 0.0046 16.6 28.1 0.0055 16.4 24.5 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Glyco_hydro_38N PF01074.22 OWF45843.1 - 1.2e-84 284.1 1.4 2e-84 283.4 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF45843.1 - 1.2e-51 175.8 0.0 2e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF45843.1 - 1e-25 89.7 0.1 4.1e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OWF45843.1 - 7.2e-11 42.1 0.0 1.8e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain 7TM_GPCR_Srw PF10324.9 OWF45844.1 - 2e-27 96.3 19.9 2.5e-27 96.0 19.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF45844.1 - 1.8e-13 50.4 17.2 2.3e-13 50.1 17.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF45844.1 - 1.3e-06 28.0 21.1 5.4e-05 22.7 13.0 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4131 PF13567.6 OWF45844.1 - 5.6 6.6 7.5 1.9 8.1 0.1 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Gal_Lectin PF02140.18 OWF45845.1 - 6.5e-05 23.3 3.5 0.00018 21.8 3.5 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain DUF1299 PF06975.11 OWF45846.1 - 0.15 12.1 13.9 0.76 9.9 2.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1299) AA_permease_N PF08403.10 OWF45846.1 - 0.3 10.6 3.5 1.7 8.2 0.6 2.6 1 1 1 2 2 2 0 Amino acid permease N-terminal DUF21 PF01595.20 OWF45847.1 - 5.9e-33 114.0 1.0 1e-32 113.2 1.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OWF45847.1 - 5.6e-06 26.7 3.4 0.021 15.3 0.3 3.7 2 1 0 2 2 2 2 CBS domain CENP-K PF11802.8 OWF45847.1 - 0.15 11.6 0.1 0.47 10.0 0.0 1.7 2 0 0 2 2 2 0 Centromere-associated protein K Vta1 PF04652.16 OWF45848.1 - 3.3e-52 176.3 0.7 3.3e-52 176.3 0.7 1.6 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OWF45848.1 - 7.7e-15 54.3 3.2 7.7e-15 54.3 3.2 2.2 2 0 0 2 2 2 1 Vta1 C-terminal domain FliS PF02561.14 OWF45848.1 - 0.0053 17.0 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Flagellar protein FliS EF-hand_7 PF13499.6 OWF45849.1 - 4.1e-09 36.8 0.1 7.3e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF45849.1 - 2.3e-08 33.0 0.5 0.0025 17.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF45849.1 - 2.4e-06 27.3 1.0 0.014 15.2 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF45849.1 - 2.9e-06 26.8 0.3 0.023 14.6 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF45849.1 - 0.0011 18.4 0.1 1.4 8.5 0.1 2.5 2 0 0 2 2 2 2 EF hand DUF498 PF04430.14 OWF45850.1 - 7.9e-27 93.5 0.0 1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Arm PF00514.23 OWF45851.1 - 2.7e-07 30.4 6.5 0.15 12.2 0.1 5.5 6 1 0 6 6 6 3 Armadillo/beta-catenin-like repeat INSC_LBD PF16748.5 OWF45851.1 - 5e-07 29.1 0.5 1.3e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 Inscuteable LGN-binding domain LRR_8 PF13855.6 OWF45852.1 - 4.4e-43 144.9 53.7 1e-13 50.8 2.6 5.2 2 1 4 6 6 6 5 Leucine rich repeat 7tm_1 PF00001.21 OWF45852.1 - 5.7e-26 91.4 12.7 8.7e-26 90.8 12.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 OWF45852.1 - 9.3e-20 70.9 8.2 2.2e-12 47.0 1.1 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF45852.1 - 1.7e-19 69.6 26.8 2.1e-06 28.0 2.2 5.6 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF45852.1 - 2.4e-08 33.4 18.5 0.77 10.5 0.1 8.0 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 OWF45852.1 - 1.7e-07 30.9 9.3 0.0015 18.1 1.8 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 OWF45852.1 - 0.00041 20.2 20.7 1.1 9.5 0.1 7.3 7 0 0 7 7 7 2 Leucine Rich repeat 7TM_GPCR_Srbc PF10316.9 OWF45852.1 - 0.016 14.8 11.8 0.037 13.5 11.8 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc S-methyl_trans PF02574.16 OWF45854.1 - 4.3e-39 134.9 0.0 5.2e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase S-methyl_trans PF02574.16 OWF45855.1 - 2.1e-38 132.7 0.0 2.6e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Redoxin PF08534.10 OWF45855.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Redoxin ISG65-75 PF11727.8 OWF45855.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein S-methyl_trans PF02574.16 OWF45856.1 - 1.6e-41 142.9 0.0 1.9e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase CCG PF02754.16 OWF45856.1 - 0.1 12.8 0.4 0.94 9.7 0.1 2.5 2 0 0 2 2 2 0 Cysteine-rich domain DUF4821 PF16092.5 OWF45856.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) S-methyl_trans PF02574.16 OWF45857.1 - 3.6e-45 154.9 0.1 7.3e-41 140.7 0.1 2.0 1 1 1 2 2 2 2 Homocysteine S-methyltransferase AP_endonuc_2 PF01261.24 OWF45857.1 - 0.00027 20.4 0.1 1.2 8.6 0.0 2.9 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel DUF4821 PF16092.5 OWF45857.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) CCG PF02754.16 OWF45857.1 - 0.11 12.7 1.7 0.47 10.7 0.1 2.6 2 0 0 2 2 2 0 Cysteine-rich domain ATP-synt_ab_Xtn PF16886.5 OWF45857.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension Toxin_24 PF08094.11 OWF45857.1 - 1.6 8.6 6.3 8.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Conotoxin TVIIA/GS family BPL_N PF09825.9 OWF45858.1 - 2.3e-60 204.7 0.1 1.7e-58 198.5 0.1 2.0 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_3 PF07685.14 OWF45858.1 - 0.00038 20.1 0.1 0.00075 19.1 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 OWF45858.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 CS PF04969.16 OWF45860.1 - 7.5e-15 55.7 0.7 1.9e-14 54.4 0.7 1.7 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 OWF45860.1 - 1.3e-12 47.5 0.7 3e-12 46.3 0.1 2.0 2 1 0 2 2 2 1 N-terminal conserved domain of Nudc. NuDC PF16273.5 OWF45860.1 - 8.3e-09 35.8 25.7 8.3e-09 35.8 25.7 3.3 2 2 1 3 3 3 1 Nuclear distribution C domain Presenilin PF01080.17 OWF45860.1 - 0.16 10.7 11.3 0.26 10.0 11.3 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OWF45860.1 - 0.34 9.0 8.3 0.41 8.7 8.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cwf_Cwc_15 PF04889.12 OWF45860.1 - 5 6.8 33.1 0.22 11.2 27.0 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Zip PF02535.22 OWF45860.1 - 7 5.8 5.4 12 5.0 5.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PhyH PF05721.13 OWF45861.1 - 4.3e-13 50.0 0.0 3e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF5010_C PF18099.1 OWF45861.1 - 0.0043 17.2 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 DUF5010 C-terminal domain Prenyltransf PF01255.19 OWF45863.1 - 1.2e-77 260.5 0.0 1.8e-77 259.9 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_S46 PF10459.9 OWF45863.1 - 0.0057 15.4 2.6 0.0087 14.8 2.6 1.2 1 0 0 1 1 1 1 Peptidase S46 Ten1_2 PF15490.6 OWF45863.1 - 0.0084 15.8 0.2 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 Telomere-capping, CST complex subunit Bromodomain PF00439.25 OWF45864.1 - 2.5e-41 139.6 1.0 4.7e-20 71.5 0.1 2.5 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 OWF45864.1 - 4.7e-36 122.2 15.8 1.9e-06 28.5 0.1 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF45864.1 - 1.1e-10 41.7 0.5 6.8e-05 23.1 0.3 5.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Auxin_resp PF06507.13 OWF45864.1 - 0.016 15.4 1.5 0.039 14.2 0.4 2.2 2 0 0 2 2 2 0 Auxin response factor DUF3104 PF11302.8 OWF45864.1 - 0.028 14.1 0.1 0.058 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) zf-MYND PF01753.18 OWF45865.1 - 1e-07 31.9 20.3 1e-07 31.9 20.3 1.7 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 OWF45865.1 - 0.5 10.7 16.5 1.2 9.5 16.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Reg_prop PF07494.11 OWF45866.1 - 0.52 10.7 43.3 13 6.4 0.3 9.6 1 1 8 9 9 9 0 Two component regulator propeller GMC_oxred_N PF00732.19 OWF45867.1 - 1.6e-77 260.8 0.0 2e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF45867.1 - 0.00027 20.1 2.2 0.091 11.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 OWF45867.1 - 0.0018 17.6 0.9 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF45867.1 - 0.0069 15.7 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF45867.1 - 0.0099 16.1 1.2 0.024 14.8 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF45867.1 - 0.013 15.1 2.5 0.14 11.8 2.4 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF45867.1 - 0.13 11.3 0.2 0.21 10.6 0.0 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein BIR PF00653.21 OWF45868.1 - 2e-27 95.6 8.0 6.6e-18 65.1 2.4 3.4 3 1 1 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF45868.1 - 9.3e-08 31.8 15.8 9.3e-08 31.8 15.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45868.1 - 0.00093 19.0 14.9 0.0028 17.5 14.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC PF07967.13 OWF45868.1 - 2.1 8.4 15.5 0.8 9.7 0.0 3.3 3 0 0 3 3 3 0 C3HC zinc finger-like zf-C3HC4_3 PF13920.6 OWF45869.1 - 6.3e-06 26.0 8.5 6.3e-06 26.0 8.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45869.1 - 0.019 14.8 10.0 0.058 13.3 10.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 WD40 PF00400.32 OWF45871.1 - 2.1e-35 120.1 2.5 5.8e-10 39.6 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF45871.1 - 1.2e-09 38.4 0.0 0.14 12.4 0.0 5.3 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF45871.1 - 0.00024 20.2 0.1 0.16 10.9 0.0 3.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 OWF45871.1 - 0.00059 18.8 0.1 2.3 7.0 0.0 3.3 1 1 2 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 OWF45871.1 - 0.0087 15.7 0.0 0.063 12.8 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain WD40_like PF17005.5 OWF45871.1 - 0.069 12.5 0.0 0.99 8.7 0.1 2.4 1 1 1 2 2 2 0 WD40-like domain Sugar_tr PF00083.24 OWF45872.1 - 9.4e-30 103.8 16.7 1.4e-29 103.3 16.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF45872.1 - 1.5e-22 80.0 35.4 1.7e-11 43.7 11.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Lectin_C PF00059.21 OWF45873.1 - 1.1e-08 35.7 1.5 2.9e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 Lectin C-type domain DUF364 PF04016.12 OWF45874.1 - 0.0052 16.4 0.2 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 Putative heavy-metal chelation Steroid_dh PF02544.16 OWF45875.1 - 2e-52 177.2 1.2 2e-52 177.2 1.2 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OWF45875.1 - 9.5e-05 22.0 0.1 9.5e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) DBD_Tnp_Hermes PF10683.9 OWF45875.1 - 0.011 15.4 0.4 0.03 14.0 0.4 1.7 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain WH1 PF00568.23 OWF45876.1 - 0.0029 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 WH1 domain AbiJ_NTD5 PF18865.1 OWF45876.1 - 0.026 14.3 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 DUF3218 PF11508.8 OWF45878.1 - 0.02 14.4 3.4 8.7 5.8 0.0 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF3218) DUF3218 PF11508.8 OWF45879.1 - 0.07 12.6 11.1 24 4.3 0.0 5.7 1 1 8 9 9 9 0 Protein of unknown function (DUF3218) NEXCaM_BD PF16644.5 OWF45879.1 - 3 8.1 6.8 42 4.4 0.1 3.4 2 1 1 3 3 3 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin DUF3218 PF11508.8 OWF45880.1 - 0.0077 15.7 10.7 6.4 6.2 0.1 5.1 1 1 5 6 6 6 6 Protein of unknown function (DUF3218) Ist1 PF03398.14 OWF45881.1 - 5.7e-64 215.0 3.9 7e-64 214.7 3.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway zf-C4H2 PF10146.9 OWF45881.1 - 0.9 9.8 3.6 3.4 7.9 3.6 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein G_path_suppress PF15991.5 OWF45881.1 - 1.4 9.0 15.1 2.4 8.2 15.0 1.5 1 1 0 1 1 1 0 G-protein pathway suppressor Sec63 PF02889.16 OWF45882.1 - 1.9e-83 279.6 0.3 4e-83 278.5 0.3 1.6 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OWF45882.1 - 1.1e-53 181.6 1.3 1.9e-27 96.1 1.1 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OWF45882.1 - 3.6e-26 92.2 0.1 4.1e-12 46.4 0.3 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 OWF45882.1 - 7.8e-13 48.6 0.0 2.2e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_22 PF13401.6 OWF45882.1 - 7.1e-09 36.1 2.8 0.00043 20.6 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OWF45882.1 - 3.4e-07 30.2 0.4 0.0011 18.7 0.4 3.1 3 0 0 3 3 3 2 AAA domain Helicase_C PF00271.31 OWF45882.1 - 1.2e-06 28.8 0.2 8.1e-05 22.9 0.0 3.8 2 2 0 2 2 2 1 Helicase conserved C-terminal domain T2SSE PF00437.20 OWF45882.1 - 8e-05 21.8 0.0 0.46 9.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 OWF45882.1 - 0.00072 19.9 2.3 0.31 11.4 0.9 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 OWF45882.1 - 0.0017 17.9 0.2 0.65 9.4 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 OWF45882.1 - 0.0027 17.3 0.2 1.3 8.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OWF45882.1 - 0.019 14.7 0.7 0.35 10.6 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein ParA PF10609.9 OWF45882.1 - 0.031 13.7 0.1 3.1 7.2 0.0 2.4 1 1 1 2 2 2 0 NUBPL iron-transfer P-loop NTPase UvrD-helicase PF00580.21 OWF45882.1 - 0.037 13.5 0.2 0.42 10.1 0.2 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain CUB PF00431.20 OWF45883.1 - 2.3e-11 44.0 0.0 4.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 CUB domain Gal_Lectin PF02140.18 OWF45883.1 - 0.00017 22.0 0.6 0.00045 20.6 0.6 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain MGC-24 PF05283.11 OWF45883.1 - 0.0084 16.6 1.5 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2970 PF11174.8 OWF45883.1 - 0.0093 15.8 2.2 0.02 14.7 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) EphA2_TM PF14575.6 OWF45883.1 - 0.12 13.2 0.2 0.32 11.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MRAP PF15183.6 OWF45883.1 - 0.16 12.0 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Calreticulin PF00262.18 OWF45884.1 - 3e-88 296.1 51.1 6 5.6 0.0 53.6 1 1 86 92 92 92 92 Calreticulin family Herpes_gE PF02480.16 OWF45885.1 - 0.00062 18.6 0.0 0.00089 18.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Gal_Lectin PF02140.18 OWF45886.1 - 3.7e-06 27.3 1.9 3.7e-06 27.3 1.9 1.7 2 0 0 2 2 2 1 Galactose binding lectin domain Sec63 PF02889.16 OWF45887.1 - 2.6e-69 233.3 0.0 3.2e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain UCH PF00443.29 OWF45888.1 - 4.4e-40 137.8 1.6 4.4e-40 137.8 1.6 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4 PF00097.25 OWF45888.1 - 3.7e-05 23.5 3.1 3.7e-05 23.5 3.1 9.6 8 2 0 8 8 8 4 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF45888.1 - 0.0049 16.8 14.6 0.0049 16.8 14.6 9.2 7 1 1 8 8 8 4 zinc-RING finger domain UCH PF00443.29 OWF45889.1 - 2.6e-29 102.5 0.7 4.3e-29 101.8 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OWF45890.1 - 1.1e-34 120.1 0.7 1.1e-34 120.1 0.7 2.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OWF45891.1 - 1e-31 110.3 0.2 1.6e-31 109.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF45891.1 - 5.4e-11 42.6 1.2 5.4e-11 42.6 1.2 2.6 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 OWF45892.1 - 6.6e-13 48.9 6.4 1.1e-08 35.4 2.4 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF45892.1 - 1.6e-12 46.0 11.1 2e-05 23.8 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF45892.1 - 8.6e-10 37.8 7.5 0.0063 16.4 0.5 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OWF45892.1 - 4.7e-06 26.3 3.6 8.6e-05 22.3 0.7 2.5 2 0 0 2 2 2 1 EF-hand domain pair EFhand_Ca_insen PF08726.10 OWF45892.1 - 0.00018 21.5 0.8 0.00049 20.1 0.3 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 OWF45892.1 - 0.00035 19.9 4.4 0.022 14.2 0.0 3.6 3 0 0 3 3 3 1 EF hand CDC37_N PF03234.14 OWF45892.1 - 1.5 9.7 12.5 0.14 13.1 2.3 3.0 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding Methyltr_RsmB-F PF01189.17 OWF45893.1 - 1.7e-24 86.6 0.0 2.4e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OWF45893.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 OWF45893.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 OWF45893.1 - 0.073 13.8 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Gal4_dimer PF03902.13 OWF45893.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain UQ_con PF00179.26 OWF45894.1 - 5.1e-17 61.8 0.0 1.2e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MRNIP PF15749.5 OWF45894.1 - 0.019 15.7 2.5 0.12 13.1 0.1 2.4 2 0 0 2 2 2 0 MRN-interacting protein zf-RanBP PF00641.18 OWF45894.1 - 0.02 14.2 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Pox_Ag35 PF03286.14 OWF45894.1 - 1.2 8.9 12.3 2.6 7.8 12.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase PF00069.25 OWF45895.1 - 5.3e-64 216.1 0.0 1.2e-63 214.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF45895.1 - 2.9e-40 138.2 0.0 5.2e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF45895.1 - 2.4e-06 27.1 0.0 1.4e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF45895.1 - 3.6e-05 22.7 0.0 0.0001 21.3 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase T3SS_basalb_I PF17001.5 OWF45895.1 - 0.0029 18.2 0.5 0.017 15.7 0.5 2.4 1 0 0 1 1 1 1 Type III secretion basal body protein I, YscI, HrpB, PscI DUF3206 PF11472.8 OWF45895.1 - 0.016 15.2 1.3 2.9 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) MnmE_helical PF12631.7 OWF45895.1 - 2 8.6 5.3 0.54 10.4 0.3 2.6 3 0 0 3 3 3 0 MnmE helical domain DNA_pol_phi PF04931.13 OWF45895.1 - 2.4 6.1 15.2 11 4.0 11.4 2.6 2 0 0 2 2 2 0 DNA polymerase phi WD40 PF00400.32 OWF45896.1 - 5.6e-07 30.2 14.7 0.44 11.5 0.0 6.7 7 1 0 7 7 7 3 WD domain, G-beta repeat fn1 PF00039.18 OWF45896.1 - 0.0023 18.1 1.6 0.0058 16.8 1.6 1.6 1 0 0 1 1 1 1 Fibronectin type I domain Ank_2 PF12796.7 OWF45897.1 - 3.1e-07 30.9 0.1 0.22 12.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF45897.1 - 9.8e-06 26.0 0.5 0.012 16.2 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF45897.1 - 0.00015 22.0 0.0 0.018 15.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF45897.1 - 0.0033 17.8 0.4 3.1 8.6 0.0 4.5 5 1 0 5 5 5 1 Ankyrin repeat DSPc PF00782.20 OWF45898.1 - 2.6e-30 105.0 0.1 3e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF45898.1 - 0.0028 17.3 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HHV6-IE PF03753.13 OWF45898.1 - 0.037 11.5 1.0 0.046 11.2 1.0 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Init_tRNA_PT PF04179.12 OWF45898.1 - 0.046 14.0 0.2 0.068 13.5 0.2 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain DSPc PF00782.20 OWF45899.1 - 1.9e-40 137.7 0.0 2.6e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF45899.1 - 0.0009 18.9 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Kazal_1 PF00050.21 OWF45900.1 - 8.1e-23 80.2 50.2 6.8e-08 32.4 5.8 5.4 2 1 3 5 5 5 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF45900.1 - 3.5e-22 78.3 49.7 1.4e-06 28.4 7.7 5.0 4 1 1 5 5 5 4 Kazal-type serine protease inhibitor domain Na_trans_assoc PF06512.13 OWF45901.1 - 1.5e-06 28.7 17.3 1.8e+04 -8.5 17.3 10.6 1 1 0 1 1 1 0 Sodium ion transport-associated preATP-grasp_3 PF18301.1 OWF45901.1 - 0.19 12.0 0.3 6.4 7.1 0.0 3.4 2 0 0 2 2 2 0 pre ATP-grasp 3 domain ARID PF01388.21 OWF45902.1 - 7.5e-25 87.4 0.0 2.1e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 OWF45902.1 - 7.5e-08 32.9 0.0 2.1e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain FOXP-CC PF16159.5 OWF45902.1 - 0.0075 16.9 11.4 0.83 10.3 2.2 3.2 1 1 1 2 2 2 2 FOXP coiled-coil domain CDC37_M PF08565.11 OWF45903.1 - 1.8e-24 85.9 0.4 1.8e-24 85.9 0.4 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OWF45903.1 - 1.3e-15 57.3 0.0 1.3e-15 57.3 0.0 4.2 3 2 2 5 5 5 1 Cdc37 C terminal domain CDC37_N PF03234.14 OWF45903.1 - 4.1e-13 50.4 28.2 1.8e-12 48.2 25.2 3.0 1 1 2 3 3 3 1 Cdc37 N terminal kinase binding DUF2894 PF11445.8 OWF45903.1 - 0.32 11.4 5.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) WD40 PF00400.32 OWF45904.1 - 7.2e-18 64.6 7.7 0.0011 19.7 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 OWF45904.1 - 1.4e-07 30.6 1.8 0.0039 15.9 0.4 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OWF45904.1 - 8.3e-06 26.0 1.1 0.00072 19.8 0.5 3.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PLAC8 PF04749.17 OWF45905.1 - 1.9e-15 57.6 16.0 2.7e-15 57.2 16.0 1.2 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 OWF45906.1 - 4.3e-12 46.9 9.8 6e-12 46.4 9.8 1.2 1 0 0 1 1 1 1 PLAC8 family RabGAP-TBC PF00566.18 OWF45907.1 - 1.9e-54 184.6 1.1 3.2e-54 183.8 1.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC_membrane PF00664.23 OWF45908.1 - 1.5e-72 244.5 49.0 4.9e-42 144.5 9.3 3.7 3 1 1 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF45908.1 - 7.8e-55 185.1 2.1 7.1e-31 107.6 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OWF45908.1 - 1e-09 38.1 6.0 0.00018 21.0 0.0 4.4 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OWF45908.1 - 1.4e-06 28.3 3.3 0.013 15.5 0.6 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OWF45908.1 - 1.2e-05 25.8 0.1 0.033 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OWF45908.1 - 2.2e-05 24.4 0.4 0.0093 15.9 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OWF45908.1 - 3.5e-05 23.5 2.4 0.12 12.1 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OWF45908.1 - 0.00011 21.5 0.3 0.018 14.3 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 OWF45908.1 - 0.00016 21.8 0.2 0.0052 16.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 OWF45908.1 - 0.00044 20.1 0.7 0.54 10.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OWF45908.1 - 0.0013 18.8 3.7 0.19 11.8 0.1 3.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 OWF45908.1 - 0.012 15.2 0.3 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OWF45908.1 - 0.017 15.4 2.6 5.5 7.3 0.2 3.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OWF45908.1 - 0.026 14.3 0.3 0.43 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 OWF45908.1 - 0.063 12.8 0.2 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 OWF45908.1 - 0.068 12.3 0.6 4.3 6.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 OWF45908.1 - 0.084 13.1 1.1 16 5.7 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OWF45908.1 - 0.096 13.2 9.8 11 6.4 0.1 3.9 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OWF45908.1 - 0.13 11.5 0.3 4.1 6.5 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 OWF45908.1 - 0.24 11.4 1.5 5.2 7.1 0.1 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Lectin_C PF00059.21 OWF45909.1 - 9.1e-06 26.4 1.2 9.1e-06 26.4 1.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 OWF45909.1 - 1.2e-05 25.0 0.3 2.7e-05 23.9 0.3 1.7 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like FSA_C PF10479.9 OWF45911.1 - 2.9 5.9 6.4 4.5 5.3 6.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sugar_tr PF00083.24 OWF45912.1 - 5.2e-32 111.3 23.3 6.9e-32 110.9 22.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF45912.1 - 1.4e-27 96.6 28.2 1.2e-15 57.4 14.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RNPHF PF08080.12 OWF45912.1 - 0.025 14.5 2.6 3.2 7.8 0.1 3.3 4 0 0 4 4 4 0 RNPHF zinc finger Sugar_tr PF00083.24 OWF45913.1 - 3.1e-33 115.3 27.1 8.5e-33 113.9 27.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF45913.1 - 4.8e-25 88.2 43.2 9.3e-22 77.4 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF45914.1 - 2.8e-39 135.3 20.6 3.5e-39 134.9 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF45914.1 - 9.4e-27 93.9 45.9 1e-22 80.5 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RNPHF PF08080.12 OWF45914.1 - 0.034 14.1 1.0 8.8 6.4 0.1 2.7 2 0 0 2 2 2 0 RNPHF zinc finger Sugar_tr PF00083.24 OWF45915.1 - 4.6e-33 114.8 8.9 7.8e-24 84.3 3.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF45915.1 - 4.1e-17 62.1 34.3 1e-09 37.8 14.2 3.4 3 1 1 4 4 4 3 Major Facilitator Superfamily PMP1_2 PF08114.11 OWF45915.1 - 0.18 11.5 2.7 0.41 10.4 0.8 2.6 2 0 0 2 2 2 0 ATPase proteolipid family SPRY PF00622.28 OWF45917.1 - 7.6e-12 45.4 1.0 2.2e-06 27.8 0.1 3.1 4 0 0 4 4 4 2 SPRY domain CcmH PF03918.14 OWF45918.1 - 0.78 9.0 22.2 1.1 8.5 1.4 5.1 1 1 4 6 6 6 0 Cytochrome C biogenesis protein CHCH PF06747.13 OWF45919.1 - 2.9e-05 24.1 4.8 5.1e-05 23.3 4.8 1.5 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 OWF45919.1 - 0.0079 16.5 2.2 0.012 15.9 2.2 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 OWF45919.1 - 0.012 16.0 2.6 0.019 15.4 2.6 1.4 1 0 0 1 1 1 0 GCK domain MTCP1 PF08991.10 OWF45919.1 - 0.038 14.2 3.1 0.056 13.7 3.1 1.3 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 OWF45919.1 - 0.14 12.2 5.0 0.32 11.0 3.6 2.0 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Tyr_Deacylase PF02580.16 OWF45920.1 - 1.8e-31 109.6 0.0 2.1e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DHC_N1 PF08385.12 OWF45922.1 - 1.9e-176 588.1 13.7 1.9e-176 588.1 13.7 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OWF45922.1 - 7.1e-144 478.8 0.0 2.6e-143 476.9 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF45922.1 - 2.3e-127 425.4 4.8 2.3e-127 425.4 4.8 4.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF45922.1 - 2.7e-94 315.8 0.0 1e-93 313.9 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF45922.1 - 9.8e-91 303.7 0.0 3e-90 302.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF45922.1 - 5.9e-86 287.1 2.0 1.4e-83 279.4 1.2 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF45922.1 - 3.7e-67 225.3 1.9 2.9e-62 209.4 0.0 4.0 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF45922.1 - 2.2e-56 190.2 0.1 5.4e-56 188.9 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF45922.1 - 3.9e-43 147.8 3.3 1e-42 146.4 3.3 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF45922.1 - 2e-40 137.6 0.9 8.5e-40 135.6 0.0 2.8 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OWF45922.1 - 1.6e-21 76.8 0.0 6e-07 29.5 0.0 5.1 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OWF45922.1 - 3.3e-19 69.0 0.1 1.9e-18 66.5 0.0 2.5 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 OWF45922.1 - 4.6e-19 68.8 0.0 4e-17 62.5 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 OWF45922.1 - 6.5e-06 26.6 0.2 1.8 9.0 0.0 5.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF45922.1 - 0.0019 18.4 0.6 90 3.3 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 OWF45922.1 - 0.01 16.2 0.6 12 6.3 0.0 4.9 5 0 0 5 5 4 0 AAA ATPase domain DUF853 PF05872.12 OWF45922.1 - 0.039 12.5 0.5 0.19 10.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Sigma54_activat PF00158.26 OWF45922.1 - 0.059 13.1 0.1 2.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF4298 PF14131.6 OWF45922.1 - 0.7 9.9 3.7 41 4.2 0.4 5.6 5 0 0 5 5 4 0 Domain of unknown function (DUF4298) YebG PF07130.12 OWF45922.1 - 1.4 8.8 6.2 0.29 11.0 0.9 2.6 2 0 0 2 2 2 0 YebG protein TetR_C_24 PF17932.1 OWF45923.1 - 0.12 12.6 3.5 0.072 13.4 0.6 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BLOC1_2 PF10046.9 OWF45923.1 - 0.13 12.5 4.6 0.22 11.9 0.5 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_Mu_Gam PF07352.12 OWF45923.1 - 5.7 6.8 10.9 5.3 6.9 2.0 3.4 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein zf-B_box PF00643.24 OWF45924.1 - 0.00017 21.7 12.5 0.00046 20.3 12.5 1.8 1 0 0 1 1 1 1 B-box zinc finger NHL PF01436.21 OWF45924.1 - 0.0023 17.9 1.2 1.1 9.5 0.0 3.7 4 0 0 4 4 4 2 NHL repeat DUF349 PF03993.12 OWF45924.1 - 0.076 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Apolipoprotein PF01442.18 OWF45924.1 - 0.52 10.2 10.2 0.98 9.3 10.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Acyltransf_C PF16076.5 OWF45925.1 - 1.2e-21 76.6 0.6 2.3e-21 75.7 0.6 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 OWF45925.1 - 2e-17 63.1 0.0 3.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase tRNA-synt_1b PF00579.25 OWF45926.1 - 3.2e-69 233.5 0.0 4e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 OWF45926.1 - 5.1e-29 100.2 0.0 1.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Cep57_CLD PF14073.6 OWF45927.1 - 1.1e-50 172.1 29.4 1.1e-50 172.1 29.4 3.1 3 0 0 3 3 3 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 OWF45927.1 - 8.1e-21 74.3 3.5 8.1e-21 74.3 3.5 4.2 2 1 1 4 4 4 1 Centrosome microtubule-binding domain of Cep57 DUF1754 PF08555.10 OWF45927.1 - 0.034 14.9 2.1 0.034 14.9 2.1 4.8 3 1 1 4 4 4 0 Eukaryotic family of unknown function (DUF1754) FAM76 PF16046.5 OWF45928.1 - 2.1e-79 267.0 70.2 1.4e-62 211.7 27.0 2.2 1 1 1 2 2 2 2 FAM76 protein NicO PF03824.16 OWF45928.1 - 0.014 14.7 0.2 0.014 14.7 0.2 1.7 2 0 0 2 2 2 0 High-affinity nickel-transport protein Cnn_1N PF07989.11 OWF45928.1 - 0.054 13.7 6.8 0.22 11.7 1.5 2.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 RraB PF06877.11 OWF45928.1 - 0.18 12.6 2.3 0.47 11.2 2.3 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B TF_Zn_Ribbon PF08271.12 OWF45928.1 - 8 6.1 8.7 0.43 10.1 2.4 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Tmp39 PF10271.9 OWF45929.1 - 2.3e-146 488.2 28.9 2.9e-146 487.9 28.9 1.0 1 0 0 1 1 1 1 Putative transmembrane protein BIR PF00653.21 OWF45930.1 - 1.2e-30 105.9 16.6 4e-19 69.0 0.5 4.3 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF45930.1 - 2.8e-10 39.9 10.7 2.8e-10 39.9 10.7 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45930.1 - 0.00011 22.0 11.3 0.00023 21.0 11.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Kazal_1 PF00050.21 OWF45931.1 - 2.6e-28 97.8 35.4 1.2e-10 41.2 7.3 4.2 1 1 3 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OWF45931.1 - 6.4e-22 77.4 34.6 2e-07 31.0 5.5 3.8 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain Toxin_11 PF07473.11 OWF45931.1 - 0.033 14.3 8.6 0.12 12.4 1.2 4.7 6 0 0 6 6 6 0 Spasmodic peptide gm9a; conotoxin from Conus species PPP1R32 PF15691.5 OWF45932.1 - 5e-168 559.6 9.4 5.7e-168 559.4 9.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 32 BIR PF00653.21 OWF45933.1 - 2.8e-35 120.8 12.9 7.8e-19 68.1 0.9 3.0 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF45933.1 - 3.4e-11 42.8 11.9 3.4e-11 42.8 11.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF45933.1 - 1.7e-06 27.8 10.5 5.6e-06 26.1 10.5 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UBA_6 PF18039.1 OWF45933.1 - 0.054 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Cep57_CLD_2 PF14197.6 OWF45933.1 - 0.24 11.5 1.6 0.99 9.5 0.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 zf-RING_2 PF13639.6 OWF45933.1 - 6.2 7.2 21.3 0.053 13.9 12.1 2.5 2 0 0 2 2 2 0 Ring finger domain adh_short_C2 PF13561.6 OWF45934.1 - 2.9e-67 226.6 0.0 3.3e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF45934.1 - 7.5e-54 182.2 0.1 8.9e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF45934.1 - 9e-13 48.5 0.0 1.2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 KR domain CBFB_NFYA PF02045.15 OWF45934.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LPMO_10 PF03067.15 OWF45935.1 - 0.0014 19.4 0.0 0.0026 18.4 0.0 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LOR PF04525.12 OWF45937.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 LURP-one-related OSTMP1 PF09777.9 OWF45938.1 - 1.8e-52 178.1 11.2 2.3e-52 177.7 11.2 1.1 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.6 OWF45938.1 - 0.015 15.1 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 CECR6/TMEM121 family Stc1 PF12898.7 OWF45938.1 - 0.25 11.9 8.9 0.078 13.5 1.9 3.2 2 1 0 3 3 3 0 Stc1 domain zf-RING_11 PF17123.5 OWF45939.1 - 0.066 13.0 2.0 0.21 11.4 2.0 1.9 1 0 0 1 1 1 0 RING-like zinc finger PHD PF00628.29 OWF45939.1 - 0.14 12.1 2.2 0.23 11.4 0.6 2.3 2 0 0 2 2 2 0 PHD-finger NuA4 PF09340.10 OWF45940.1 - 1.3e-27 95.4 0.8 2.9e-27 94.3 0.8 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Hid1 PF12722.7 OWF45940.1 - 0.87 7.6 2.2 0.96 7.5 2.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_LMP1 PF05297.11 OWF45940.1 - 6.3 5.9 6.6 8.2 5.5 6.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF5072 PF16807.5 OWF45942.1 - 0.017 15.1 0.0 9.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5072) ANF_receptor PF01094.28 OWF45943.1 - 7e-59 199.7 0.0 9.9e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 OWF45943.1 - 3e-53 179.7 0.6 5.8e-53 178.7 0.6 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF45943.1 - 6.7e-36 123.0 0.0 1.3e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF45943.1 - 9.7e-24 84.0 0.0 2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 OWF45943.1 - 0.0031 17.2 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein Lig_chan PF00060.26 OWF45944.1 - 5.2e-59 198.4 0.6 9.3e-59 197.5 0.6 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF45944.1 - 3.4e-39 133.6 0.0 8.1e-39 132.4 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 OWF45944.1 - 1.6e-28 99.8 0.4 2.6e-28 99.2 0.4 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 OWF45944.1 - 2.3e-19 69.7 0.0 4.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 VirE1 PF12189.8 OWF45944.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Single-strand DNA-binding protein T4_baseplate PF12322.8 OWF45944.1 - 0.087 12.3 0.3 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 T4 bacteriophage base plate protein LTD PF00932.19 OWF45944.1 - 0.13 12.6 0.0 0.77 10.1 0.0 2.2 2 0 0 2 2 2 0 Lamin Tail Domain DUF3552 PF12072.8 OWF45945.1 - 0.00038 19.9 0.0 1.2 8.5 0.0 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF3552) DUF4744 PF15918.5 OWF45945.1 - 1.2 10.0 4.7 2.3 9.1 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) DUF4744 PF15918.5 OWF45946.1 - 0.78 10.6 7.9 1.3 10.0 7.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) DUF3552 PF12072.8 OWF45947.1 - 0.01 15.3 0.0 0.25 10.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF3552 PF12072.8 OWF45948.1 - 4.4e-06 26.3 0.0 0.14 11.5 0.0 3.7 2 1 2 4 4 4 3 Domain of unknown function (DUF3552) S-antigen PF05756.11 OWF45948.1 - 0.065 13.6 1.0 0.065 13.6 1.0 5.2 1 1 4 6 6 6 0 S-antigen protein Fungal_trans_2 PF11951.8 OWF45949.1 - 0.013 14.3 2.6 0.058 12.2 0.3 2.2 1 1 1 2 2 2 0 Fungal specific transcription factor domain p47_phox_C PF08944.11 OWF45949.1 - 0.34 10.4 1.7 1.1 8.7 0.0 2.4 3 0 0 3 3 3 0 NADPH oxidase subunit p47Phox, C terminal domain YrzK PF17449.2 OWF45950.1 - 0.0006 20.1 1.3 1.3e+02 3.0 0.0 5.3 1 1 5 6 6 6 0 Uncharacterized YrzK-like ARTD15_N PF18084.1 OWF45950.1 - 0.003 17.8 3.0 3.6 7.9 0.5 3.8 1 1 2 3 3 3 3 ARTD15 N-terminal domain DUF2826 PF11442.8 OWF45950.1 - 0.012 15.4 2.0 18 5.1 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2826) Lectin_C PF00059.21 OWF45951.1 - 1.2e-08 35.7 0.0 1.6e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF45951.1 - 0.035 13.7 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF5319 PF17252.2 OWF45951.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Lectin_C PF00059.21 OWF45952.1 - 0.0015 19.2 0.0 0.0052 17.5 0.0 2.0 1 1 1 2 2 2 1 Lectin C-type domain THAP PF05485.12 OWF45953.1 - 1.1e-12 48.8 0.5 1.6e-12 48.2 0.1 1.5 2 0 0 2 2 2 1 THAP domain GN3L_Grn1 PF08701.11 OWF45953.1 - 0.0048 17.0 0.1 0.0062 16.6 0.1 1.2 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase CTD_bind PF04818.13 OWF45954.1 - 7.5e-14 52.3 2.5 1.1e-12 48.6 0.3 2.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 OWF45954.1 - 6.1e-09 36.2 0.5 1.6e-08 34.8 0.5 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CHGN PF05679.16 OWF45955.1 - 3.8e-179 596.8 0.1 4.6e-179 596.5 0.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 OWF45955.1 - 2.4e-14 53.4 0.1 9.9e-14 51.4 0.1 1.9 2 0 0 2 2 2 1 Fringe-like Glyco_transf_7C PF02709.14 OWF45955.1 - 1.2e-09 37.6 0.1 3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF45955.1 - 0.00056 19.5 0.2 0.55 9.7 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF45955.1 - 0.0018 18.1 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Galactosyl_T PF01762.21 OWF45955.1 - 0.0028 17.5 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Galactosyltransferase DUF3657 PF12394.8 OWF45955.1 - 0.095 13.3 0.0 0.39 11.3 0.0 2.1 1 0 0 1 1 1 0 Protein FAM135 GTP_EFTU PF00009.27 OWF45956.1 - 1.6e-60 204.0 0.7 4.6e-60 202.5 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OWF45956.1 - 2.3e-15 56.7 0.1 1e-12 48.2 0.1 3.0 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_C PF00679.24 OWF45956.1 - 5.2e-14 52.0 0.0 2.1e-13 50.1 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OWF45956.1 - 7.8e-08 32.3 0.0 2.8e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OWF45956.1 - 0.0018 18.3 0.0 0.0058 16.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 OWF45956.1 - 0.0049 16.6 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV STOP PF05217.12 OWF45957.1 - 0.00064 20.0 7.4 0.00064 20.0 7.4 4.1 4 0 0 4 4 4 2 STOP protein Cu_amine_oxid PF01179.20 OWF45958.1 - 6.3e-97 325.1 1.9 7.8e-97 324.8 1.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OWF45958.1 - 8.5e-07 29.1 0.0 2.1e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 OWF45958.1 - 4.3e-05 23.2 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Takusan PF04822.13 OWF45958.1 - 0.05 13.5 0.3 0.14 12.1 0.3 1.8 1 0 0 1 1 1 0 Takusan Cu_amine_oxid PF01179.20 OWF45959.1 - 3.7e-39 134.8 8.4 3.5e-36 125.0 3.9 2.0 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.20 OWF45960.1 - 3e-08 33.0 0.2 3.9e-08 32.6 0.2 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.20 OWF45961.1 - 1.5e-68 231.6 1.4 5.8e-68 229.7 1.4 1.7 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OWF45961.1 - 7.3e-07 29.3 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain VirB8 PF04335.13 OWF45961.1 - 0.15 11.9 0.3 0.37 10.6 0.1 1.7 2 0 0 2 2 2 0 VirB8 protein DUF4090 PF13319.6 OWF45962.1 - 1.4e-07 31.7 4.9 9.9 6.5 0.0 9.5 1 1 8 11 11 11 2 Protein of unknown function (DUF4090) DUF1758 PF05585.12 OWF45962.1 - 3.2e-05 23.8 34.2 0.22 11.3 1.4 6.9 1 1 7 8 8 8 8 Putative peptidase (DUF1758) 2HCT PF03390.15 OWF45962.1 - 3.9 6.0 6.9 4.6 5.8 0.4 2.8 3 0 0 3 3 3 0 2-hydroxycarboxylate transporter family Cu_amine_oxid PF01179.20 OWF45963.1 - 5.9e-62 209.9 1.4 7.2e-62 209.6 1.4 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OWF45964.1 - 1.3e-06 28.6 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 OWF45965.1 - 6.9e-109 364.5 0.4 8.6e-109 364.2 0.4 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OWF45965.1 - 6.1e-07 29.6 0.0 1.7e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 OWF45965.1 - 8.3e-05 22.3 0.1 0.00023 20.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) MARVEL PF01284.23 OWF45965.1 - 0.032 14.2 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Membrane-associating domain SBF PF01758.16 OWF45966.1 - 9.6e-36 123.3 16.4 9.6e-36 123.3 16.4 2.3 1 1 1 2 2 2 1 Sodium Bile acid symporter family zf-ANAPC11 PF12861.7 OWF45967.1 - 1.1e-07 31.8 1.8 1.7e-07 31.2 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger LRR_9 PF14580.6 OWF45968.1 - 2.8e-11 43.3 0.1 3.8e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF45968.1 - 1.5e-09 38.0 11.8 6.3e-05 23.3 1.1 3.6 2 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF45968.1 - 2.9e-07 30.2 10.0 0.00052 19.7 0.9 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OWF45968.1 - 0.0048 16.9 7.4 2.1 8.6 0.1 4.4 3 1 1 4 4 4 2 Leucine Rich repeat P53_tetramer PF07710.11 OWF45968.1 - 0.031 13.6 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 P53 tetramerisation motif LRR_1 PF00560.33 OWF45968.1 - 5.6 7.9 7.6 14 6.7 0.5 4.4 3 2 0 3 3 3 0 Leucine Rich Repeat HAUS6_N PF14661.6 OWF45969.1 - 2e-55 187.9 1.7 2e-55 187.9 1.7 2.0 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus DUF1390 PF07150.11 OWF45969.1 - 0.18 11.5 0.8 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) DUF4241 PF14025.6 OWF45969.1 - 0.19 12.0 0.0 0.51 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) TRAP_beta PF05753.14 OWF45970.1 - 3e-67 225.5 0.0 3.9e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 OWF45970.1 - 0.029 14.6 0.0 0.046 14.0 0.0 1.4 1 1 0 1 1 1 0 CARDB Collagen PF01391.18 OWF45971.1 - 9.7e-24 82.9 61.1 4.8e-08 32.6 12.3 4.0 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.6 OWF45971.1 - 1.7e-16 60.2 38.4 1.7e-10 41.0 10.2 3.4 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF45971.1 - 2.3e-14 53.0 14.6 8.7e-09 35.2 1.0 3.2 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF45971.1 - 5.6e-12 45.7 35.9 4.8e-07 29.9 9.9 3.4 3 0 0 3 3 3 3 Calcium-binding EGF domain EGF PF00008.27 OWF45971.1 - 2.6e-05 24.4 32.1 0.0014 18.9 5.3 3.7 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 OWF45971.1 - 0.00031 20.9 30.7 0.024 14.8 5.3 3.7 3 0 0 3 3 3 3 EGF domain Tme5_EGF_like PF09064.10 OWF45971.1 - 1.4 8.9 14.8 2.1 8.3 3.7 2.5 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like hEGF PF12661.7 OWF45971.1 - 3.3 8.5 30.2 0.072 13.8 6.6 4.5 3 1 0 3 3 3 0 Human growth factor-like EGF TIL PF01826.17 OWF45971.1 - 5.2 7.4 20.2 5.3 7.4 6.5 2.6 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain TSP_1 PF00090.19 OWF45972.1 - 1.4e-21 76.4 87.6 9.8e-06 25.7 3.5 7.6 6 3 0 6 6 6 5 Thrombospondin type 1 domain PLAC PF08686.11 OWF45972.1 - 1e-09 38.9 9.5 1e-09 38.9 9.5 2.5 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain ADAM_spacer1 PF05986.14 OWF45972.1 - 5.3e-07 29.7 0.0 8.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Galactosyl_T PF01762.21 OWF45973.1 - 4.1e-28 98.5 0.1 1.3e-27 96.8 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase Galactosyl_T PF01762.21 OWF45974.1 - 3.1e-26 92.4 0.1 4.3e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 OWF45975.1 - 1.1e-43 149.4 0.2 2e-43 148.5 0.2 1.5 1 0 0 1 1 1 1 Galactosyltransferase 7TMR-DISM_7TM PF07695.11 OWF45976.1 - 0.023 14.6 1.7 0.023 14.6 1.7 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling Carboxyl_trans PF01039.22 OWF45977.1 - 7.7e-70 235.9 0.0 7.5e-65 219.4 0.1 2.0 2 0 0 2 2 2 2 Carboxyl transferase domain DMAP1 PF05499.12 OWF45978.1 - 1.3e-74 249.6 7.8 2.1e-74 248.9 7.8 1.4 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 OWF45978.1 - 1.9e-29 101.6 4.0 6.7e-29 99.9 4.0 2.0 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Intron_maturas2 PF01348.21 OWF45978.1 - 0.077 13.0 3.9 0.071 13.1 2.5 1.7 2 0 0 2 2 2 0 Type II intron maturase Myb_DNA-bind_6 PF13921.6 OWF45978.1 - 0.2 11.9 2.4 0.29 11.4 0.7 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain Seryl_tRNA_N PF02403.22 OWF45978.1 - 0.94 9.7 9.8 1.3 9.3 6.5 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PI3K_C2 PF00792.24 OWF45979.1 - 0.013 15.4 0.0 1.8 8.5 0.0 2.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 zf-C2H2 PF00096.26 OWF45980.1 - 0.00099 19.4 4.2 0.0019 18.5 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF45980.1 - 0.048 14.5 3.5 0.087 13.7 3.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger 3HCDH_N PF02737.18 OWF45980.1 - 0.051 13.5 0.1 0.073 13.0 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CtIP_N PF10482.9 OWF45980.1 - 0.064 13.3 4.2 0.13 12.4 3.9 1.7 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Zn-ribbon_8 PF09723.10 OWF45980.1 - 0.2 11.8 1.0 0.51 10.5 0.7 1.8 2 0 0 2 2 2 0 Zinc ribbon domain DUF4573 PF15140.6 OWF45981.1 - 3.9e-06 26.8 6.6 1.9 8.3 0.1 5.8 1 1 5 6 6 6 6 Domain of unknown function (DUF4573) DUF3093 PF11292.8 OWF45981.1 - 1.1 9.5 9.5 3.1e+02 1.6 0.0 9.5 2 2 4 9 9 9 0 Protein of unknown function (DUF3093) Crystall PF00030.19 OWF45982.1 - 1.4e-29 102.1 0.0 9.5e-17 61.0 0.0 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 OWF45982.1 - 6.6e-05 22.7 6.2 0.01 15.8 1.0 3.5 2 2 2 4 4 4 2 Peptidase inhibitor family I36 IL4_i_Ig PF18258.1 OWF45982.1 - 0.00021 21.4 0.4 0.56 10.5 0.1 3.4 1 1 2 3 3 3 2 Interleukin-4 inducing immunoglobulin-binding domain CBM_6 PF03422.15 OWF45982.1 - 0.013 15.8 1.9 0.83 10.0 0.2 2.5 1 1 1 2 2 2 0 Carbohydrate binding module (family 6) Methyltransf_21 PF05050.12 OWF45983.1 - 0.0035 17.4 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Bac_DnaA_C PF08299.11 OWF45984.1 - 0.079 13.0 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix GAS PF13851.6 OWF45985.1 - 8.7e-05 22.0 1.1 0.00023 20.6 1.1 1.7 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Lzipper-MIP1 PF14389.6 OWF45985.1 - 0.0018 18.5 13.1 0.63 10.4 0.2 5.6 5 1 0 5 5 5 2 Leucine-zipper of ternary complex factor MIP1 Ribosomal_S28e PF01200.18 OWF45985.1 - 0.012 15.6 0.7 3.8 7.6 0.1 3.6 3 0 0 3 3 3 0 Ribosomal protein S28e DUF5631 PF18645.1 OWF45985.1 - 0.014 15.7 0.1 1.8 9.0 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5631) ZapB PF06005.12 OWF45985.1 - 0.017 15.5 3.3 0.017 15.5 3.3 3.1 4 1 0 4 4 4 0 Cell division protein ZapB GCN5L1 PF06320.13 OWF45985.1 - 0.019 15.1 1.7 0.052 13.7 1.7 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) CENP-F_leu_zip PF10473.9 OWF45985.1 - 0.043 13.8 2.6 0.42 10.6 2.0 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mis14 PF08641.12 OWF45985.1 - 0.088 13.1 4.5 0.051 13.9 1.5 2.2 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Seryl_tRNA_N PF02403.22 OWF45985.1 - 0.1 12.8 1.0 0.19 11.9 0.2 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Chorion_3 PF05387.11 OWF45985.1 - 0.13 11.8 2.8 3.8 7.1 0.4 2.6 2 1 0 2 2 2 0 Chorion family 3 PspA_IM30 PF04012.12 OWF45985.1 - 0.18 11.3 3.4 0.085 12.4 0.6 2.0 2 0 0 2 2 2 0 PspA/IM30 family SCAB_CC PF16712.5 OWF45985.1 - 0.28 11.0 2.9 1.1 9.1 2.9 1.9 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Pilin_GH PF16734.5 OWF45985.1 - 0.92 9.8 7.1 3.3 8.1 0.8 3.3 3 0 0 3 3 3 0 Type IV pilin-like G and H, putative Exonuc_VII_L PF02601.15 OWF45985.1 - 1.8 8.0 6.4 0.79 9.2 0.6 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit C2 PF00168.30 OWF45986.1 - 1.9e-53 179.1 6.0 5.1e-27 94.2 0.3 4.2 4 0 0 4 4 4 3 C2 domain Membr_traf_MHD PF10540.9 OWF45986.1 - 7.4e-48 162.5 1.5 7.4e-48 162.5 1.5 2.5 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.17 OWF45986.1 - 1e-32 112.7 3.9 4.9e-32 110.5 0.5 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 OWF45986.1 - 1.1e-10 41.2 6.5 2.2e-10 40.2 6.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pox_F11 PF04943.12 OWF45986.1 - 0.014 14.5 1.1 0.026 13.6 1.1 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein Pur_DNA_glyco PF02245.16 OWF45987.1 - 7.7e-58 194.8 0.0 1e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Cpn60_TCP1 PF00118.24 OWF45988.1 - 6.4e-125 417.6 2.6 7.3e-125 417.4 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase_Tyr PF07714.17 OWF45989.1 - 1e-40 139.7 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF45989.1 - 2.4e-26 92.7 0.0 4.2e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF45989.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF45989.1 - 0.11 11.9 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1q PF00386.21 OWF45990.1 - 1.3e-10 41.6 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF45990.1 - 5.6e-05 23.0 0.0 8.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 BclA C-terminal domain Fibrinogen_C PF00147.18 OWF45991.1 - 4.3e-54 183.7 1.8 6.8e-54 183.0 1.8 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF45991.1 - 0.049 13.6 0.5 0.049 13.6 0.5 1.8 2 0 0 2 2 2 0 PAN domain zf_CCCH_5 PF18384.1 OWF45991.1 - 9.8 6.4 7.2 0.42 10.8 0.5 2.2 3 0 0 3 3 3 0 Unkempt Zinc finger domain 1 (Znf1) I-set PF07679.16 OWF45992.1 - 3.1e-36 123.3 0.2 9e-12 44.9 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF45992.1 - 1.6e-34 118.3 0.8 1e-12 48.5 0.1 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 OWF45992.1 - 2.2e-24 85.4 0.6 1.1e-06 28.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF45992.1 - 3.9e-21 75.2 0.6 6.9e-08 32.7 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF45992.1 - 1.2e-12 48.0 4.6 0.0011 19.1 0.1 4.5 3 3 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF45992.1 - 0.00013 21.4 0.0 0.022 14.3 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 OWF45992.1 - 0.0071 16.7 0.1 14 6.2 0.0 3.7 3 1 0 3 3 3 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 OWF45992.1 - 0.061 13.4 0.0 20 5.3 0.0 2.7 2 0 0 2 2 2 0 C17orf99 Ig domain GHL5 PF14872.6 OWF45992.1 - 0.16 10.0 0.0 0.3 9.1 0.0 1.3 2 0 0 2 2 2 0 Hypothetical glycoside hydrolase 5 zf-B_box PF00643.24 OWF45993.1 - 5e-06 26.6 20.5 0.00013 22.0 4.5 4.1 4 1 0 4 4 3 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF45993.1 - 2.6e-05 24.0 6.5 2.6e-05 24.0 6.5 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF45993.1 - 0.00026 20.9 3.5 0.00026 20.9 3.5 3.5 3 2 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF45993.1 - 0.0021 18.4 6.9 0.0021 18.4 6.9 4.4 5 0 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 OWF45993.1 - 0.0025 17.7 6.2 0.0025 17.7 6.2 4.4 4 0 0 4 4 4 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF45993.1 - 0.0066 16.3 4.8 0.0066 16.3 4.8 3.9 3 2 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OWF45993.1 - 0.02 14.7 4.3 0.02 14.7 4.3 4.5 5 1 0 5 5 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF45993.1 - 0.033 14.3 5.4 0.033 14.3 5.4 4.2 4 2 0 4 4 3 0 zinc finger of C3HC4-type, RING PI3K_P85_iSH2 PF16454.5 OWF45993.1 - 0.2 11.2 9.5 0.65 9.6 2.5 2.7 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CEBP_ZZ PF16366.5 OWF45993.1 - 1.5 9.2 21.8 0.12 12.6 2.2 3.6 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF4637 PF15470.6 OWF45993.1 - 6.8 6.4 24.8 0.21 11.3 1.2 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4637) Ammonium_transp PF00909.21 OWF45994.1 - 3e-110 368.7 31.1 3.9e-110 368.3 31.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family zf-C2H2_assoc3 PF16637.5 OWF45994.1 - 2.5 8.3 6.8 0.14 12.4 1.2 1.8 2 0 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz DUF999 PF06198.11 OWF45997.1 - 0.099 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF999) CAP PF00188.26 OWF45998.1 - 2.3e-23 83.4 2.7 4.2e-23 82.6 2.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PI3_PI4_kinase PF00454.27 OWF45999.1 - 2.4e-55 188.0 0.1 4.2e-55 187.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OWF45999.1 - 6.7e-45 153.8 9.9 6.7e-45 153.8 9.9 2.8 4 0 0 4 4 4 1 FAT domain UME PF08064.13 OWF45999.1 - 6.7e-16 58.1 1.3 6e-15 55.0 0.4 3.0 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 OWF45999.1 - 2e-15 56.3 0.0 4.4e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_15 PF13429.6 OWF45999.1 - 0.00046 19.5 0.6 0.26 10.5 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF45999.1 - 0.044 14.6 2.1 84 4.4 0.0 5.5 6 2 1 7 7 7 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 OWF45999.1 - 0.084 13.1 0.0 2.6 8.3 0.0 2.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_19 PF14559.6 OWF45999.1 - 0.1 13.1 0.7 4.1 8.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OWF45999.1 - 0.12 12.7 3.8 3.9 7.9 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF45999.1 - 0.51 10.3 3.1 8.8 6.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat YL1_C PF08265.11 OWF46001.1 - 0.029 14.2 1.0 17 5.3 0.0 4.0 4 0 0 4 4 4 0 YL1 nuclear protein C-terminal domain E3_binding PF02817.17 OWF46001.1 - 0.054 13.9 0.0 1.5e+02 2.9 0.0 4.2 5 0 0 5 5 5 0 e3 binding domain DUF5127 PF17168.4 OWF46001.1 - 0.07 12.9 0.0 34 4.1 0.0 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF5127) ResB PF05140.14 OWF46001.1 - 0.37 9.5 0.9 0.43 9.2 0.9 1.1 1 0 0 1 1 1 0 ResB-like family Toxin_33 PF08121.11 OWF46001.1 - 6.1 6.7 15.9 44 4.0 0.3 4.2 4 0 0 4 4 4 0 Waglerin family Homeodomain PF00046.29 OWF46002.1 - 1e-22 79.7 4.0 1.6e-22 79.1 4.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF46002.1 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Pheromone PF08015.11 OWF46002.1 - 0.027 15.5 1.7 0.063 14.3 1.4 1.8 1 1 0 1 1 1 0 Fungal mating-type pheromone Homez PF11569.8 OWF46002.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez RACo_C_ter PF14574.6 OWF46003.1 - 0.0064 15.6 0.3 1.4 7.9 0.1 2.4 1 1 1 2 2 2 2 C-terminal domain of RACo the ASKHA domain DUF5442 PF17514.2 OWF46003.1 - 0.048 13.9 0.1 7.7 6.8 0.0 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5442) DUF3889 PF13028.6 OWF46003.1 - 0.048 13.6 0.1 7.6 6.6 0.0 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3889) FAD_binding_5 PF00941.21 OWF46006.1 - 1.9e-49 167.7 0.0 2.8e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OWF46006.1 - 5.8e-29 99.9 0.1 1.4e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 OWF46006.1 - 2.2e-10 40.3 1.0 2.2e-10 40.3 1.0 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Cation_efflux PF01545.21 OWF46007.1 - 1.2e-23 83.9 13.6 2.4e-23 82.9 13.6 1.5 1 1 0 1 1 1 1 Cation efflux family 7tm_1 PF00001.21 OWF46008.1 - 1.3e-25 90.2 24.8 1.7e-25 89.8 24.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF46008.1 - 9.1e-06 25.6 22.8 0.00027 20.8 11.6 2.6 2 1 0 2 2 2 2 Olfactory receptor Renin_r PF07850.14 OWF46008.1 - 0.047 14.3 4.4 1.3 9.7 0.4 2.8 2 0 0 2 2 2 0 Renin receptor-like protein DUF4328 PF14219.6 OWF46008.1 - 2.9 7.4 7.8 10 5.6 6.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4328) Ank_2 PF12796.7 OWF46009.1 - 7e-123 401.5 31.6 3.7e-16 59.5 0.9 8.0 1 1 11 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF46009.1 - 2.6e-73 241.5 11.6 1.3e-13 51.1 0.0 9.1 5 2 4 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 OWF46009.1 - 9.9e-66 215.5 16.5 2e-05 24.8 0.0 13.8 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.6 OWF46009.1 - 5.6e-54 173.8 15.3 0.0023 18.3 0.0 13.2 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 OWF46009.1 - 6.6e-53 176.1 22.1 1.7e-08 34.5 0.0 12.7 3 2 11 14 14 14 13 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF46009.1 - 2.7e-07 30.8 0.0 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 SOCS box DUF1843 PF08898.10 OWF46009.1 - 0.14 12.6 0.5 5.3 7.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) GPI2 PF06432.11 OWF46011.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase MRF_C1 PF13887.6 OWF46012.1 - 1.7e-06 27.1 7.1 0.78 9.0 0.1 5.3 6 0 0 6 6 6 3 Myelin gene regulatory factor -C-terminal domain 1 Jag_N PF14804.6 OWF46012.1 - 0.001 19.4 3.4 34 4.9 0.1 4.8 5 0 0 5 5 5 0 Jag N-terminus DprA_WH PF17782.1 OWF46012.1 - 0.048 13.8 0.0 34 4.7 0.0 3.2 1 1 4 5 5 5 0 DprA winged helix domain PspA_IM30 PF04012.12 OWF46012.1 - 0.049 13.2 11.2 0.11 12.1 11.2 1.4 1 1 0 1 1 1 0 PspA/IM30 family DicB PF05358.11 OWF46012.1 - 0.055 13.6 9.8 20 5.4 0.2 4.6 1 1 4 5 5 5 0 DicB protein KilA-N PF04383.13 OWF46012.1 - 0.059 13.2 8.1 22 5.0 0.1 3.2 1 1 1 2 2 2 0 KilA-N domain F-box_5 PF18511.1 OWF46012.1 - 0.088 12.4 0.8 1.7e+02 1.8 0.0 4.4 5 0 0 5 5 5 0 F-box CO_deh_flav_C PF03450.17 OWF46012.1 - 0.16 12.2 1.6 2.7 8.2 0.4 2.1 1 1 1 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain MTCP1 PF08991.10 OWF46012.1 - 0.22 11.8 12.9 16 5.8 0.1 4.9 1 1 4 5 5 5 0 Mature-T-Cell Proliferation I type DUF5082 PF16888.5 OWF46012.1 - 0.32 11.3 13.3 1.5 9.1 0.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF2387 PF09526.10 OWF46012.1 - 0.51 10.5 12.7 1.5 9.0 1.6 3.1 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) CLU PF13236.6 OWF46012.1 - 0.67 9.8 8.4 3.3 7.5 2.1 2.5 1 1 2 3 3 3 0 Clustered mitochondria NA37 PF04245.13 OWF46012.1 - 1.4 8.3 8.6 2.7 7.4 1.5 2.0 1 1 1 2 2 2 0 37-kD nucleoid-associated bacterial protein Coatomer_g_Cpla PF16381.5 OWF46012.1 - 4.1 7.6 6.9 37 4.5 0.5 3.0 1 1 2 3 3 3 0 Coatomer subunit gamma-1 C-terminal appendage platform HTH_Bact PF18768.1 OWF46012.1 - 5.8 6.6 9.4 1.1e+02 2.5 0.1 4.6 5 0 0 5 5 5 0 Helix-turn-helix bacterial domain FATC PF02260.20 OWF46012.1 - 6.2 6.7 11.7 38 4.2 0.1 4.6 6 0 0 6 6 6 0 FATC domain Lectin_C PF00059.21 OWF46013.1 - 4.5e-21 75.6 1.9 6.9e-21 75.0 1.9 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF46013.1 - 0.012 15.3 0.6 0.031 13.9 0.6 1.7 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like EGF PF00008.27 OWF46014.1 - 5.9e-44 148.0 67.2 6.5e-08 32.7 2.7 7.0 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 OWF46014.1 - 2.8e-17 62.6 69.8 0.00033 21.1 1.3 8.1 7 0 0 7 7 7 6 Human growth factor-like EGF EGF_CA PF07645.15 OWF46014.1 - 1.1e-11 44.7 73.3 0.0007 19.7 7.6 6.8 4 1 2 6 6 6 5 Calcium-binding EGF domain EGF_2 PF07974.13 OWF46014.1 - 9.2e-08 32.3 87.6 0.00091 19.5 6.4 7.4 7 0 0 7 7 7 5 EGF-like domain EGF_3 PF12947.7 OWF46014.1 - 0.019 15.2 60.3 0.52 10.6 6.3 7.0 5 1 1 6 6 6 0 EGF domain LGFP PF08310.11 OWF46014.1 - 0.051 14.1 0.4 0.2 12.2 0.4 2.0 1 0 0 1 1 1 0 LGFP repeat PKD PF00801.20 OWF46014.1 - 0.055 13.3 0.1 14 5.6 0.0 3.0 2 0 0 2 2 2 0 PKD domain 7tm_1 PF00001.21 OWF46015.1 - 1.3e-34 119.7 9.8 1.8e-34 119.3 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF46015.1 - 9.8e-08 31.9 14.2 1.5e-07 31.3 14.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF46015.1 - 0.0014 18.4 6.7 0.0026 17.6 6.7 1.5 1 1 0 1 1 1 1 Olfactory receptor Podoplanin PF05808.11 OWF46015.1 - 1.7 8.8 3.2 12 6.0 2.7 2.2 2 0 0 2 2 2 0 Podoplanin THAP PF05485.12 OWF46017.1 - 2.2e-10 41.3 0.7 2.3e-10 41.3 0.7 1.0 1 0 0 1 1 1 1 THAP domain Hexapep PF00132.24 OWF46018.1 - 5.1e-11 41.8 2.9 0.075 12.8 0.0 6.4 2 2 4 7 7 7 3 Bacterial transferase hexapeptide (six repeats) LRR_5 PF13306.6 OWF46018.1 - 6.5e-07 29.4 4.3 8e-06 25.8 4.3 2.3 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Carm_PH PF17888.1 OWF46018.1 - 1.5e-06 28.4 6.8 9.4 6.7 0.1 6.7 1 1 5 6 6 6 1 Carmil pleckstrin homology domain Rieske_2 PF13806.6 OWF46018.1 - 0.00016 21.5 1.4 0.81 9.7 0.1 4.0 1 1 0 2 2 2 2 Rieske-like [2Fe-2S] domain Sec23_helical PF04815.15 OWF46018.1 - 0.0004 20.2 0.7 15 5.5 0.0 5.5 2 1 6 8 8 8 1 Sec23/Sec24 helical domain DUF3974 PF13120.6 OWF46018.1 - 0.002 18.2 4.6 5.7 7.1 0.1 4.3 1 1 5 6 6 6 2 Domain of unknown function (DUF3974) Flg_bbr_C PF06429.13 OWF46018.1 - 0.0051 16.9 12.7 6.2 7.0 1.0 4.9 1 1 2 3 3 3 3 Flagellar basal body rod FlgEFG protein C-terminal DUF1667 PF07892.11 OWF46018.1 - 0.016 15.2 7.0 0.78 9.8 0.4 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1667) DUF3783 PF12646.7 OWF46018.1 - 0.19 11.7 4.8 49 4.0 0.1 4.3 2 2 3 5 5 5 0 Domain of unknown function (DUF3783) Connexin50 PF03509.14 OWF46018.1 - 1.7 9.5 4.2 52 4.7 1.5 3.4 1 1 2 3 3 3 0 Gap junction alpha-8 protein (Cx50) STG PF15809.5 OWF46019.1 - 2.2e-15 57.4 243.7 12 5.9 0.5 36.1 1 1 59 61 61 61 60 Simian taste bud-specific gene product family SIX1_SD PF16878.5 OWF46019.1 - 0.034 14.7 0.1 1.3e+02 3.1 0.1 8.1 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain WW PF00397.26 OWF46020.1 - 1e-15 57.5 0.1 2.5e-10 40.3 0.0 2.7 2 0 0 2 2 2 2 WW domain C2 PF00168.30 OWF46020.1 - 7.6e-07 29.4 0.0 2.3e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF3829 PF12889.7 OWF46020.1 - 4.4 6.7 11.2 0.85 9.0 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) BTB PF00651.31 OWF46021.1 - 1.6e-12 47.7 0.2 3.6e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Slx4 PF09494.10 OWF46021.1 - 5.9e-10 38.9 0.3 1.5e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Nudix_N_2 PF14803.6 OWF46021.1 - 0.037 14.0 1.4 0.52 10.3 0.1 2.8 2 0 0 2 2 2 0 Nudix N-terminal Sgf11 PF08209.11 OWF46021.1 - 0.085 12.4 1.7 6.9 6.3 0.1 3.7 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C2H2_jaz PF12171.8 OWF46021.1 - 0.91 9.9 4.0 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OWF46021.1 - 1.4 9.5 6.2 0.42 11.2 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type UBZ_FAAP20 PF15750.5 OWF46021.1 - 1.5 8.9 5.2 12 6.0 0.2 3.7 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger LRR_9 PF14580.6 OWF46023.1 - 2.8e-11 43.2 3.0 4.9e-11 42.4 1.0 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OWF46023.1 - 1.6e-08 34.7 4.7 4e-05 23.9 0.7 4.1 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF46023.1 - 2.1e-06 27.4 3.2 2.3e-06 27.3 0.7 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 OWF46023.1 - 0.87 9.8 8.7 42 4.6 0.5 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Lectin_C PF00059.21 OWF46025.1 - 1.9e-07 31.8 0.3 4.7e-07 30.5 0.3 1.7 1 0 0 1 1 1 1 Lectin C-type domain CytochromB561_N PF09786.9 OWF46025.1 - 2.2 7.2 11.2 5.2 5.9 11.2 1.5 1 1 0 1 1 1 0 Cytochrome B561, N terminal Porin_3 PF01459.22 OWF46026.1 - 9.6e-72 241.7 0.4 1.1e-71 241.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin A_deaminase PF00962.22 OWF46027.1 - 9.2e-120 399.9 0.6 3.3e-119 398.1 0.6 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase RAB3GAP2_C PF14656.6 OWF46027.1 - 0.056 11.7 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF3466 PF11949.8 OWF46027.1 - 0.098 11.3 0.0 0.22 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3466) Ank_2 PF12796.7 OWF46028.1 - 9.3e-09 35.8 1.0 6.6 7.4 0.3 6.9 6 1 0 6 6 6 2 Ankyrin repeats (3 copies) ATPase_2 PF01637.18 OWF46028.1 - 0.0016 18.4 0.2 0.13 12.2 0.0 2.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OWF46028.1 - 0.0019 18.1 0.3 0.0065 16.4 0.1 2.1 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 OWF46028.1 - 0.0023 17.2 0.1 0.0058 15.8 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 OWF46028.1 - 0.0027 16.8 0.2 0.006 15.7 0.2 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OWF46028.1 - 0.012 15.5 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OWF46028.1 - 0.019 15.4 0.1 0.094 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OWF46028.1 - 0.027 14.8 0.1 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 OWF46028.1 - 0.029 14.4 0.0 0.092 12.8 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 OWF46028.1 - 0.8 10.2 0.0 0.8 10.2 0.0 2.7 3 0 0 3 3 3 0 ABC transporter ABC_trans_CmpB PF06541.11 OWF46029.1 - 9.4e-06 25.9 18.5 5.1e-05 23.5 18.5 2.6 1 1 0 1 1 1 1 Putative ABC-transporter type IV 3-HAO PF06052.12 OWF46030.1 - 1.5e-64 216.2 0.3 2.5e-61 205.7 0.2 2.1 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 OWF46030.1 - 1.7e-10 40.5 0.2 3.3e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OWF46030.1 - 9.3e-06 25.3 0.3 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OWF46030.1 - 4.9e-05 23.2 0.0 0.061 13.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.22 OWF46030.1 - 0.0071 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 OWF46030.1 - 0.013 15.7 0.0 0.83 9.9 0.0 2.6 2 1 0 2 2 2 0 Mif2/CENP-C like GTP_EFTU PF00009.27 OWF46031.1 - 3.1e-34 118.2 5.3 9.3e-33 113.4 3.2 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OWF46031.1 - 3.2e-29 101.1 1.2 3.2e-29 101.1 1.2 2.5 3 0 0 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OWF46031.1 - 8.1e-10 38.8 0.2 1.8e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF46031.1 - 5.2e-05 23.2 1.5 0.004 17.1 0.1 2.6 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 OWF46031.1 - 0.0003 20.3 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OWF46031.1 - 0.0007 19.3 0.5 0.0022 17.7 0.5 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OWF46031.1 - 0.00074 19.0 0.1 0.0027 17.2 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 OWF46031.1 - 0.0013 18.8 0.0 0.0063 16.5 0.0 2.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 OWF46031.1 - 0.0016 18.0 0.3 0.0052 16.3 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 OWF46031.1 - 0.0083 16.3 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 OWF46031.1 - 0.058 13.5 1.0 3.7 7.6 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Nup54_57_C PF18570.1 OWF46031.1 - 0.14 11.8 0.8 0.38 10.4 0.8 1.8 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Rpp20 PF12328.8 OWF46032.1 - 1.6e-17 63.7 0.0 1.1e-10 41.6 0.0 2.4 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 OWF46032.1 - 6.8e-11 41.8 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Alba DUF2031 PF09592.10 OWF46032.1 - 0.0081 15.7 1.0 1.7 8.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2031) EGF PF00008.27 OWF46033.1 - 8.7e-82 268.9 252.8 9.5e-11 41.8 3.4 18.8 17 1 0 18 18 18 15 EGF-like domain hEGF PF12661.7 OWF46033.1 - 6.4e-56 185.2 218.2 5.5e-08 33.2 3.9 19.9 19 0 0 19 19 19 14 Human growth factor-like EGF MNNL PF07657.13 OWF46033.1 - 1.6e-26 92.2 3.5 1.6e-26 92.2 3.5 5.9 6 0 0 6 6 6 1 N terminus of Notch ligand DSL PF01414.19 OWF46033.1 - 1e-24 86.6 5.1 1e-24 86.6 5.1 13.2 10 3 3 13 13 13 2 Delta serrate ligand EGF_2 PF07974.13 OWF46033.1 - 1.3e-14 54.3 299.7 0.00097 19.5 4.6 19.6 19 0 0 19 19 19 13 EGF-like domain EGF_CA PF07645.15 OWF46033.1 - 1.3e-14 54.1 264.5 0.00048 20.3 4.7 18.6 9 4 10 19 19 19 11 Calcium-binding EGF domain cEGF PF12662.7 OWF46033.1 - 3.9e-06 26.7 1.0 3.9e-06 26.7 1.0 17.0 16 3 0 16 16 16 4 Complement Clr-like EGF-like Astacin PF01400.24 OWF46034.1 - 2.1e-47 161.2 0.0 2.8e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Astacin PF01400.24 OWF46035.1 - 1.2e-26 93.5 0.3 1.3e-26 93.4 0.3 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OWF46035.1 - 0.14 12.0 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Matrixin Astacin PF01400.24 OWF46036.1 - 1.9e-48 164.6 0.0 2.5e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXMR_C2 PF16098.5 OWF46036.1 - 0.025 15.1 2.2 0.052 14.0 2.2 1.5 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 Peptidase_M10 PF00413.24 OWF46036.1 - 0.13 12.1 0.3 0.43 10.4 0.3 1.5 1 1 0 1 1 1 0 Matrixin FtsX PF02687.21 OWF46038.1 - 0.023 15.1 9.7 0.054 14.0 1.4 2.4 2 1 0 2 2 2 0 FtsX-like permease family DUF3754 PF12576.8 OWF46038.1 - 0.38 10.7 1.6 0.52 10.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Antifungal_prot PF11402.8 OWF46039.1 - 3.3 8.0 19.8 14 6.0 1.6 3.1 1 1 2 3 3 3 0 Antifungal protein Metallothio_2 PF01439.18 OWF46040.1 - 0.033 15.1 0.5 0.14 13.1 0.5 2.1 1 0 0 1 1 1 0 Metallothionein SDF PF00375.18 OWF46041.1 - 1.9e-64 218.1 6.7 2.1e-64 218.0 6.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4718 PF15842.5 OWF46041.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) RRM_1 PF00076.22 OWF46042.1 - 1e-24 86.1 0.0 3.7e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 OWF46042.1 - 5.7e-19 68.9 3.8 1.2e-18 67.8 3.8 1.5 1 0 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins PHM7_cyt PF14703.6 OWF46042.1 - 0.0097 16.1 0.0 0.68 10.1 0.0 2.5 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter WD40 PF00400.32 OWF46043.1 - 7.2e-22 77.3 8.9 7.4e-08 32.9 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46043.1 - 4.3e-09 36.5 3.2 0.18 12.2 0.2 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF46043.1 - 0.00011 21.7 3.0 0.16 11.3 0.0 2.3 1 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 OWF46043.1 - 0.00056 19.0 2.0 0.5 9.3 0.4 3.1 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 OWF46043.1 - 0.003 17.6 1.9 1.4 9.0 0.1 3.6 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DUF5050 PF16472.5 OWF46043.1 - 0.012 14.9 2.6 0.88 8.8 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5050) Ig_Tie2_1 PF10430.9 OWF46043.1 - 0.12 12.7 3.0 10 6.6 0.8 2.7 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Tmemb_14 PF03647.13 OWF46044.1 - 2.7e-29 101.8 12.0 3e-29 101.6 12.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C 7TM-7TMR_HD PF07698.11 OWF46044.1 - 0.0013 18.5 3.3 0.0013 18.5 3.3 1.0 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase OCIA PF07051.11 OWF46044.1 - 0.012 15.7 2.3 0.06 13.4 0.3 2.1 1 1 1 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) PMT_2 PF13231.6 OWF46044.1 - 0.093 12.9 2.1 0.11 12.7 2.1 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase ThrE PF06738.12 OWF46044.1 - 0.21 10.9 5.1 0.26 10.6 5.1 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF4203 PF13886.6 OWF46044.1 - 0.52 9.9 10.7 0.084 12.5 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) PAC3 PF10178.9 OWF46045.1 - 2.1e-19 69.4 0.1 2.9e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Pkinase_Tyr PF07714.17 OWF46046.1 - 5.1e-88 294.7 0.0 7.1e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF46046.1 - 1.1e-36 126.5 0.0 2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 OWF46046.1 - 5e-23 81.2 7.2 1.2e-22 80.0 7.2 1.7 1 0 0 1 1 1 1 Kringle domain I-set PF07679.16 OWF46046.1 - 1.7e-22 79.3 0.0 8.3e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF46046.1 - 1.1e-20 74.0 0.8 2.2e-09 37.8 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF46046.1 - 1.5e-12 47.6 0.4 2.3e-06 27.8 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Fz PF01392.22 OWF46046.1 - 2.6e-10 40.9 4.5 8.4e-10 39.3 4.5 1.9 1 0 0 1 1 1 1 Fz domain ig PF00047.25 OWF46046.1 - 7.7e-09 35.6 1.1 0.003 17.7 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF46046.1 - 1.1e-05 25.6 2.7 0.12 12.5 0.4 4.1 3 1 0 3 3 3 2 Immunoglobulin V-set domain C1-set PF07654.15 OWF46046.1 - 0.00024 21.4 0.1 0.33 11.4 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin C1-set domain C2-set_2 PF08205.12 OWF46046.1 - 0.052 13.6 0.1 2 8.6 0.0 2.6 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Haspin_kinase PF12330.8 OWF46046.1 - 0.066 12.2 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-H2C2_2 PF13465.6 OWF46047.1 - 1.8e-30 104.0 61.9 7.9e-08 32.4 3.2 9.8 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2 PF00096.26 OWF46047.1 - 3.4e-25 87.1 79.2 9.8e-05 22.6 3.8 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF46047.1 - 1e-21 75.7 75.7 0.00043 20.9 0.4 9.8 9 0 0 9 9 9 8 C2H2-type zinc finger Homeodomain PF00046.29 OWF46047.1 - 1.8e-15 56.5 0.3 8.2e-15 54.4 0.3 2.3 1 0 0 1 1 1 1 Homeodomain zf-C2H2_jaz PF12171.8 OWF46047.1 - 9e-07 29.0 52.2 0.01 16.1 0.8 9.0 9 0 0 9 9 8 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 OWF46047.1 - 0.00088 18.8 37.5 1.6 8.4 0.1 8.3 8 0 0 8 8 8 5 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 OWF46047.1 - 0.001 19.4 52.1 0.061 13.7 2.3 8.3 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF46047.1 - 0.0042 17.0 7.5 0.0062 16.5 2.5 8.6 9 0 0 9 9 9 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OWF46047.1 - 0.014 15.2 38.6 0.35 10.8 0.1 8.1 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 OWF46047.1 - 0.14 11.9 49.6 0.086 12.6 1.1 7.8 8 0 0 8 8 8 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 OWF46047.1 - 0.24 11.5 36.4 0.37 11.0 5.7 6.6 4 2 1 5 5 5 0 Zinc ribbon domain CpXC PF14353.6 OWF46047.1 - 1.1 9.3 29.3 0.95 9.5 0.1 7.3 3 2 4 8 8 8 0 CpXC protein zinc_ribbon_4 PF13717.6 OWF46047.1 - 1.1 9.2 30.8 4.7 7.2 0.0 7.1 6 2 1 7 7 7 0 zinc-ribbon domain DUF3621 PF12285.8 OWF46047.1 - 1.2 9.5 3.9 0.63 10.5 0.2 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3621) HypA PF01155.19 OWF46047.1 - 1.8 8.6 27.5 41 4.2 0.1 5.3 3 2 2 5 5 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 OWF46047.1 - 3.2 8.1 42.4 0.029 14.6 2.7 5.4 3 2 3 6 6 5 0 Drought induced 19 protein (Di19), zinc-binding DUF2180 PF09947.9 OWF46047.1 - 3.8 7.6 10.4 5.7 7.0 0.8 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zinc_ribbon_15 PF17032.5 OWF46047.1 - 4.6 8.0 30.2 18 6.1 4.7 5.7 3 2 2 5 5 5 0 zinc-ribbon family TerY_C PF15616.6 OWF46047.1 - 7 6.8 9.7 0.5 10.5 0.2 3.2 2 1 2 4 4 4 0 TerY-C metal binding domain zf-CCHC_4 PF14392.6 OWF46048.1 - 0.036 13.8 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M64 PF09471.10 OWF46048.1 - 0.049 13.2 0.1 0.049 13.2 0.1 1.5 2 0 0 2 2 2 0 IgA Peptidase M64 Nucleoside_tran PF01733.18 OWF46049.1 - 0.003 17.0 1.0 1.3e+02 1.8 0.0 6.4 1 1 8 10 10 10 1 Nucleoside transporter DLH PF01738.18 OWF46050.1 - 0.024 14.2 0.1 0.041 13.4 0.1 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family HMw1_D2 PF18254.1 OWF46050.1 - 0.62 10.5 4.2 1.9 8.9 0.5 2.2 2 0 0 2 2 2 0 HMW1 domain 2 FtsK_alpha PF17854.1 OWF46051.1 - 2.5e-06 27.5 4.9 4.8 7.4 0.1 5.4 1 1 5 6 6 6 3 FtsK alpha domain Homeobox_KN PF05920.11 OWF46052.1 - 2.2e-16 59.4 1.8 4.5e-16 58.5 1.8 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF46052.1 - 1.1e-05 25.2 0.1 2.4e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Homeodomain AZUL PF16558.5 OWF46052.1 - 0.057 13.7 0.4 0.18 12.1 0.4 1.8 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A E_Pc_C PF06752.12 OWF46053.1 - 2.2e-27 96.7 28.5 3.2e-27 96.1 28.5 1.2 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus EPL1 PF10513.9 OWF46053.1 - 2.4e-12 47.5 2.2 2.4e-12 47.5 2.2 3.2 4 0 0 4 4 4 1 Enhancer of polycomb-like CAF1A PF12253.8 OWF46053.1 - 0.077 13.2 0.2 0.29 11.3 0.2 2.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A AP3D1 PF06375.11 OWF46053.1 - 0.15 12.3 0.1 0.15 12.3 0.1 3.5 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Ser_hydrolase PF06821.13 OWF46054.1 - 2.5e-10 40.5 0.0 3.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase DUF1057 PF06342.12 OWF46054.1 - 0.0023 17.0 0.1 0.0076 15.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 OWF46054.1 - 0.0045 16.7 0.2 0.18 11.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF46054.1 - 0.0079 16.8 0.0 0.021 15.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF46054.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 polyprenyl_synt PF00348.17 OWF46055.1 - 6.2e-72 241.7 0.7 7.7e-72 241.4 0.7 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase QVR PF17064.5 OWF46056.1 - 2.1e-23 82.4 7.9 2.8e-23 82.0 7.9 1.2 1 0 0 1 1 1 1 Sleepless protein DuoxA PF10204.9 OWF46057.1 - 2.3e-73 246.6 6.9 2.8e-73 246.3 6.9 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Trp_oprn_chp PF09534.10 OWF46057.1 - 3.9 7.3 5.2 0.52 10.1 0.2 2.1 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) An_peroxidase PF03098.15 OWF46058.1 - 7.6e-125 417.5 0.0 1.3e-124 416.7 0.0 1.4 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 OWF46058.1 - 1.9e-20 73.6 0.0 4.5e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OWF46058.1 - 1.5e-17 63.7 0.1 4.6e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 OWF46058.1 - 8.7e-16 58.2 15.3 2e-15 57.0 15.3 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 OWF46058.1 - 4.3e-07 30.3 1.8 8.2e-07 29.4 0.2 2.5 2 1 1 3 3 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF46058.1 - 3.6e-06 26.7 0.4 0.0005 19.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF46058.1 - 7.6e-06 25.1 2.8 0.001 18.5 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 OWF46058.1 - 8.4e-06 25.3 0.3 0.37 10.9 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain FAD_binding_6 PF00970.24 OWF46058.1 - 0.13 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_5 PF13202.6 OWF46058.1 - 0.23 11.0 1.2 11 5.7 0.0 3.0 3 0 0 3 3 3 0 EF hand TMEM208_SND2 PF05620.11 OWF46058.1 - 3.6 7.3 5.1 3.3 7.5 2.5 2.3 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 BCDHK_Adom3 PF10436.9 OWF46059.1 - 1.8e-48 164.5 0.2 2.7e-48 163.9 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OWF46059.1 - 1.9e-14 54.1 0.0 3.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OWF46059.1 - 0.0013 18.5 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2603 PF10788.9 OWF46059.1 - 0.064 13.3 1.1 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) DUF4806 PF16064.5 OWF46059.1 - 0.074 13.4 0.2 0.17 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) Peptidase_M41 PF01434.18 OWF46060.1 - 1.4e-55 188.1 2.0 3.2e-55 186.9 2.0 1.6 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OWF46060.1 - 1.1e-41 142.3 0.0 3.3e-41 140.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF46060.1 - 6.6e-09 35.4 0.2 1.6e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OWF46060.1 - 2.3e-05 24.9 0.4 0.0016 18.8 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 OWF46060.1 - 0.00011 21.6 0.1 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 OWF46060.1 - 0.00021 21.3 0.0 0.00092 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OWF46060.1 - 0.0004 20.2 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OWF46060.1 - 0.003 17.8 0.0 0.19 12.0 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OWF46060.1 - 0.0045 17.0 0.0 0.023 14.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 OWF46060.1 - 0.011 16.3 0.0 0.068 13.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_2 PF07724.14 OWF46060.1 - 0.012 15.8 0.0 0.044 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OWF46060.1 - 0.025 14.3 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 OWF46060.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OWF46060.1 - 0.072 13.3 0.3 0.47 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 OWF46060.1 - 0.095 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OWF46060.1 - 0.13 11.8 0.1 5 6.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 OWF46060.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 OWF46060.1 - 0.14 12.0 0.1 0.45 10.4 0.0 1.9 2 0 0 2 2 1 0 NTPase FYVE PF01363.21 OWF46061.1 - 0.067 13.3 9.4 0.76 10.0 9.4 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-CCHC_2 PF13696.6 OWF46061.1 - 1.7 8.5 7.4 6.6 6.7 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-AN1 PF01428.16 OWF46061.1 - 4.7 7.5 12.1 6.9 6.9 6.7 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger COesterase PF00135.28 OWF46062.1 - 7.9e-70 236.2 1.4 5.2e-66 223.6 0.3 2.2 2 0 0 2 2 2 2 Carboxylesterase family ORC4_C PF14629.6 OWF46063.1 - 1.7e-50 171.4 0.5 2.7e-50 170.8 0.5 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OWF46063.1 - 1.9e-13 51.1 1.4 7.8e-13 49.2 1.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OWF46063.1 - 8.7e-11 42.4 0.0 1.6e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF46063.1 - 2e-09 37.8 0.1 4.1e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OWF46063.1 - 1.8e-06 27.3 0.0 3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 OWF46063.1 - 4.9e-05 23.3 3.0 0.0001 22.3 0.7 2.6 2 1 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 OWF46063.1 - 5.6e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DAP3 PF10236.9 OWF46063.1 - 0.00037 19.8 0.1 0.34 10.0 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 OWF46063.1 - 0.00065 19.7 0.0 0.0027 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 OWF46063.1 - 0.0087 15.5 0.2 0.061 12.7 0.1 2.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 OWF46063.1 - 0.015 15.4 0.0 0.046 13.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OWF46063.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Cdc6_C PF09079.11 OWF46063.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain AAA_7 PF12775.7 OWF46063.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 OWF46063.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OWF46063.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 OWF46063.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Herpes_BLLF1 PF05109.13 OWF46064.1 - 1.4e-05 23.3 100.7 0.016 13.3 27.2 3.5 1 1 2 3 3 3 3 Herpes virus major outer envelope glycoprotein (BLLF1) VirE1 PF12189.8 OWF46064.1 - 0.013 15.5 20.7 38 4.5 0.1 9.3 3 2 9 12 12 12 0 Single-strand DNA-binding protein Baculo_PEP_C PF04513.12 OWF46064.1 - 0.92 9.5 3.5 1.4 8.9 0.1 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRRC37AB_C PF14914.6 OWF46065.1 - 0.021 14.7 0.2 0.021 14.7 0.2 1.9 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Lambda_Bor PF06291.11 OWF46065.1 - 0.1 12.6 0.2 0.14 12.2 0.2 1.2 1 0 0 1 1 1 0 Bor protein TMEM51 PF15345.6 OWF46065.1 - 1.8 8.4 4.1 1.5 8.6 0.7 1.9 1 1 1 2 2 2 0 Transmembrane protein 51 AI-2E_transport PF01594.16 OWF46066.1 - 0.0048 16.1 0.7 0.0057 15.8 0.7 1.0 1 0 0 1 1 1 1 AI-2E family transporter PH PF00169.29 OWF46067.1 - 3.5e-09 37.1 0.2 1e-08 35.6 0.2 1.9 1 0 0 1 1 1 1 PH domain LSDAT_euk PF18139.1 OWF46068.1 - 7.5e-85 284.5 1.1 1.3e-84 283.8 1.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF46068.1 - 1.6e-31 109.1 0.9 3e-31 108.2 0.9 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 OWF46068.1 - 1.2e-14 54.2 26.2 2.5e-14 53.1 26.2 1.6 1 1 0 1 1 1 1 Ion transport protein NUDIX PF00293.28 OWF46068.1 - 0.00079 19.5 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain LDcluster4 PF18306.1 OWF46068.1 - 0.0098 15.5 0.7 1.1 8.8 0.2 2.3 2 0 0 2 2 2 2 SLOG cluster4 family MFS_1 PF07690.16 OWF46069.1 - 4.1e-22 78.6 23.1 4.1e-22 78.6 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OAR PF03826.17 OWF46069.1 - 0.21 11.4 0.1 0.48 10.3 0.1 1.6 1 0 0 1 1 1 0 OAR domain Amidohydro_1 PF01979.20 OWF46070.1 - 2.6e-64 217.7 0.0 3.4e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OWF46070.1 - 3.4e-08 33.4 0.0 0.00079 19.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Ald_Xan_dh_C2 PF02738.18 OWF46071.1 - 1.1e-171 572.1 0.0 1.4e-171 571.7 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 OWF46071.1 - 7.2e-08 32.8 0.2 3.9e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Ald_Xan_dh_C2 PF02738.18 OWF46072.1 - 1.7e-80 271.1 0.0 2.6e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OWF46072.1 - 9.6e-38 129.6 0.0 1.5e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OWF46072.1 - 4.4e-28 97.1 0.4 1.4e-27 95.5 0.1 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 OWF46072.1 - 8.2e-28 97.0 0.0 1.7e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OWF46072.1 - 2.2e-13 50.3 0.2 1.1e-12 48.0 0.0 2.5 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OWF46072.1 - 1.9e-09 37.3 0.1 6.4e-09 35.6 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.18 OWF46073.1 - 7.8e-83 278.8 0.1 9.7e-83 278.5 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD-oxidase_C PF02913.19 OWF46074.1 - 2.3e-55 187.9 0.0 3.2e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OWF46074.1 - 1.9e-36 124.8 0.0 3.1e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Ald_Xan_dh_C2 PF02738.18 OWF46075.1 - 6.8e-176 586.0 1.2 1e-175 585.4 1.2 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OWF46075.1 - 2.7e-31 108.6 0.0 4.9e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OWF46075.1 - 7e-30 102.9 0.2 2.2e-29 101.3 0.2 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 OWF46075.1 - 4.5e-27 94.6 0.0 8.8e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OWF46075.1 - 9.9e-17 61.0 0.0 3.9e-16 59.1 0.0 2.1 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OWF46075.1 - 2.3e-09 37.1 0.5 1e-08 35.0 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 OWF46075.1 - 0.18 11.6 5.6 0.085 12.7 1.0 2.6 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B TatD_DNase PF01026.21 OWF46076.1 - 2.3e-14 53.4 0.0 2.6e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Lipase_GDSL PF00657.22 OWF46078.1 - 2.7e-05 24.3 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF46078.1 - 9.9e-05 22.8 0.0 0.00013 22.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pyridoxal_deC PF00282.19 OWF46079.1 - 2.4e-110 368.8 0.0 2.8e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OWF46079.1 - 0.0041 16.1 0.0 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OWF46079.1 - 0.022 14.0 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 OWF46079.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Lectin_C PF00059.21 OWF46080.1 - 4.3e-19 69.2 6.1 1.6e-11 44.9 0.3 3.5 3 0 0 3 3 3 3 Lectin C-type domain WSC PF01822.19 OWF46080.1 - 9.5e-05 22.5 3.4 0.00035 20.7 2.8 2.4 2 0 0 2 2 2 1 WSC domain Protocadherin PF08374.11 OWF46080.1 - 0.034 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Cadherin_C_2 PF16492.5 OWF46080.1 - 0.044 14.5 0.1 1.6 9.5 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF473 PF04322.12 OWF46081.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF473) Tubulin_C PF03953.17 OWF46082.1 - 3.4e-50 169.4 0.0 5.1e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 OWF46082.1 - 3.2e-11 43.8 0.0 4.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain MFS_1 PF07690.16 OWF46084.1 - 3e-16 59.3 22.5 3e-16 59.3 22.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1242 PF06842.12 OWF46084.1 - 0.9 9.4 6.8 2.2 8.1 6.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) MFS_1 PF07690.16 OWF46085.1 - 1.5e-18 66.9 43.8 8.3e-12 44.7 20.4 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily Disaggr_repeat PF06848.11 OWF46085.1 - 0.054 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Disaggregatase related repeat DUF829 PF05705.14 OWF46087.1 - 1e-47 163.1 0.0 1.2e-47 162.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF5578 PF17741.1 OWF46088.1 - 1.3e-132 441.2 4.2 2e-132 440.6 4.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Drf_GBD PF06371.13 OWF46088.1 - 2.8e-06 27.0 0.3 5.7e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain HEAT_2 PF13646.6 OWF46088.1 - 0.0008 19.7 3.6 0.11 12.9 0.0 4.1 3 2 1 4 4 4 2 HEAT repeats Arm PF00514.23 OWF46088.1 - 0.0021 18.1 0.1 0.81 9.8 0.1 4.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 OWF46088.1 - 0.098 12.6 1.3 0.27 11.1 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) 7tm_1 PF00001.21 OWF46089.1 - 4.6e-55 186.8 20.5 5.8e-55 186.4 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF46089.1 - 3.3e-05 23.8 9.9 6.4e-05 22.8 9.9 1.5 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF46089.1 - 0.00013 21.7 19.7 0.00013 21.7 19.7 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx BIV_Env PF05858.12 OWF46089.1 - 0.049 11.8 3.0 0.063 11.5 3.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) ACT_3 PF10000.9 OWF46090.1 - 1.2 9.1 7.4 13 5.7 0.2 3.4 1 1 2 3 3 3 0 ACT domain DUF1908 PF08926.11 OWF46091.1 - 3.3e-111 371.0 0.0 3.3e-111 371.0 0.0 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 OWF46091.1 - 3.7e-48 164.2 0.0 9.9e-27 93.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF46091.1 - 2.7e-18 66.2 0.0 5.8e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PDZ_6 PF17820.1 OWF46091.1 - 8.1e-09 35.2 0.1 2e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF46091.1 - 3.7e-07 30.4 0.0 1.1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF46091.1 - 4.6e-06 26.9 0.1 1.4e-05 25.3 0.1 1.9 1 0 0 1 1 1 1 PDZ domain DUF5572 PF17733.1 OWF46091.1 - 0.083 12.7 1.3 12 5.9 0.3 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5572) Pro_isomerase PF00160.21 OWF46092.1 - 2.6e-51 174.0 0.1 4.9e-51 173.1 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OWF46092.1 - 5.4e-11 42.9 1.8 0.095 13.6 0.3 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OWF46092.1 - 0.017 14.1 0.2 4.1 6.3 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OWF46092.1 - 0.021 15.1 0.0 0.35 11.2 0.0 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C54 PF03416.19 OWF46093.1 - 8.7e-109 363.2 0.1 1.6e-108 362.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C54 Glyco_hydro_35 PF01301.19 OWF46093.1 - 0.11 12.1 3.7 0.2 11.2 3.7 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Miga PF10265.9 OWF46093.1 - 0.42 9.5 7.1 7.2 5.5 4.7 2.2 2 0 0 2 2 2 0 Mitoguardin Ribosomal_L27A PF00828.19 OWF46094.1 - 4.9e-21 75.7 0.0 6.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Toxin_TOLIP PF00087.21 OWF46095.1 - 0.0031 17.7 12.7 0.011 16.0 12.7 2.0 1 0 0 1 1 1 1 Snake toxin and toxin-like protein PAS_9 PF13426.7 OWF46096.1 - 5.4e-08 33.0 3.3 1.6 9.0 0.8 5.9 1 1 1 2 2 2 2 PAS domain PAS_2 PF08446.11 OWF46096.1 - 0.0032 18.1 12.9 9.5 6.9 1.2 5.3 1 1 4 5 5 5 3 PAS fold Vps51 PF08700.11 OWF46096.1 - 0.011 15.8 9.8 7.1 6.8 0.1 6.0 1 1 6 7 7 7 0 Vps51/Vps67 CoA_binding PF02629.19 OWF46096.1 - 0.11 13.2 0.9 52 4.6 0.1 3.3 1 1 1 3 3 3 0 CoA binding domain Gp5_C PF06715.12 OWF46096.1 - 0.54 10.5 0.2 0.54 10.5 0.2 5.6 3 2 5 8 8 8 0 Gp5 C-terminal repeat (3 copies) CSTF2_hinge PF14327.6 OWF46096.1 - 7.6 7.1 17.7 6.6 7.3 2.0 4.9 1 1 3 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 PDZ PF00595.24 OWF46097.1 - 4.9e-12 46.0 0.0 8.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 OWF46097.1 - 2.6e-09 38.1 0.1 1e-08 36.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 OWF46097.1 - 2.2e-07 30.6 0.0 6.4e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF46097.1 - 1.5e-06 28.4 0.1 6e-06 26.5 0.0 2.0 3 0 0 3 3 3 1 PDZ domain UbiA PF01040.18 OWF46098.1 - 1.9e-55 187.9 14.9 2.8e-55 187.4 14.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2408 PF10303.9 OWF46098.1 - 0.15 12.6 0.1 0.27 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Rpr2 PF04032.16 OWF46099.1 - 8.3e-19 67.7 2.9 1.2e-18 67.2 2.9 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain F-box-like_2 PF13013.6 OWF46099.1 - 0.089 12.8 1.2 0.12 12.3 1.2 1.4 1 1 0 1 1 1 0 F-box-like domain SelR PF01641.18 OWF46100.1 - 2.4e-19 69.6 2.0 2.9e-19 69.3 2.0 1.2 1 0 0 1 1 1 1 SelR domain DUF983 PF06170.12 OWF46100.1 - 0.018 15.5 0.9 1.7 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Zn_ribbon_recom PF13408.6 OWF46100.1 - 0.024 15.2 2.0 2.7 8.6 0.6 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.12 OWF46100.1 - 0.034 13.6 1.1 0.53 9.8 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 OWF46100.1 - 0.038 13.4 5.2 1.4 8.4 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain RIG-I_C-RD PF11648.8 OWF46100.1 - 0.091 13.0 1.4 0.76 10.0 1.6 1.9 1 1 1 2 2 2 0 C-terminal domain of RIG-I zf-Mss51 PF13824.6 OWF46100.1 - 0.23 11.6 5.1 0.32 11.1 0.7 2.4 1 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_4 PF13717.6 OWF46100.1 - 0.27 11.2 2.4 2.2 8.3 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 OWF46100.1 - 0.41 10.6 0.2 0.41 10.6 0.2 2.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit FWWh PF14922.6 OWF46101.1 - 2.4e-46 157.3 2.9 5.9e-46 156.0 2.9 1.7 1 0 0 1 1 1 1 Protein of unknown function dNK PF01712.19 OWF46102.1 - 8.6e-53 179.2 0.4 1.1e-52 178.9 0.4 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 OWF46102.1 - 4.2e-06 27.0 0.0 4.4e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OWF46102.1 - 9.4e-06 26.2 0.5 0.00029 21.4 0.5 2.4 1 1 0 1 1 1 1 AAA domain DUF2753 PF10952.8 OWF46102.1 - 0.0017 18.5 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) Thymidylate_kin PF02223.17 OWF46102.1 - 0.0056 16.4 0.1 0.021 14.5 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase AAA_22 PF13401.6 OWF46102.1 - 0.017 15.4 0.1 0.081 13.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 OWF46102.1 - 0.03 14.8 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OWF46102.1 - 0.039 14.3 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 OWF46102.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OWF46102.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OWF46103.1 - 6.2e-101 338.1 0.9 8e-101 337.7 0.9 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OWF46103.1 - 7.9e-13 48.2 0.2 6.8e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OWF46103.1 - 0.00015 22.0 0.1 0.72 10.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OWF46103.1 - 0.00048 19.6 0.9 0.056 12.8 0.2 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF46103.1 - 0.00059 19.4 0.1 0.066 12.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 OWF46103.1 - 0.0025 17.5 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OWF46103.1 - 0.039 13.7 0.1 6.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 3-dmu-9_3-mt PF06983.13 OWF46104.1 - 9.5e-05 22.9 69.2 43 4.7 0.1 21.6 2 1 20 24 24 24 2 3-demethylubiquinone-9 3-methyltransferase Gp5_C PF06715.12 OWF46104.1 - 0.012 15.7 2.7 0.012 15.7 2.7 56.8 29 17 32 68 68 68 0 Gp5 C-terminal repeat (3 copies) ATPase PF06745.13 OWF46104.1 - 0.18 11.2 34.8 15 4.8 0.0 13.4 7 4 10 17 17 17 0 KaiC Calycin_like PF13944.6 OWF46105.1 - 2.2e-07 31.2 4.8 0.27 11.5 0.0 5.2 1 1 4 5 5 5 4 Calycin-like beta-barrel domain Imm50 PF15594.6 OWF46105.1 - 4.1e-05 23.8 6.1 8.7 6.6 0.2 5.7 1 1 3 4 4 4 3 Immunity protein 50 GcnA_N PF18229.1 OWF46105.1 - 0.00017 21.5 2.1 47 4.1 0.0 6.2 2 1 4 7 7 7 0 N-acetyl-beta-D-glucosaminidase N-terminal domain H_lectin PF09458.10 OWF46105.1 - 0.00097 19.3 24.4 2.3 8.4 0.3 10.5 2 1 4 6 6 6 1 H-type lectin domain Arcadin_1 PF18653.1 OWF46105.1 - 0.028 14.5 8.2 17 5.5 0.0 6.1 2 2 3 6 6 6 0 Arcadin 1 DUF1110 PF06533.12 OWF46105.1 - 2.8 7.9 12.8 9.3 6.2 0.0 6.2 4 2 2 7 7 7 0 Protein of unknown function (DUF1110) PrpR_N PF06506.11 OWF46105.1 - 3.1 7.3 6.2 30 4.1 0.0 4.8 6 2 1 7 7 7 0 Propionate catabolism activator Calycin_like PF13944.6 OWF46106.1 - 0.00016 22.0 7.1 0.3 11.4 0.4 4.9 1 1 3 4 4 4 2 Calycin-like beta-barrel domain LSM14 PF12701.7 OWF46106.1 - 0.96 9.6 2.4 46 4.2 0.1 3.3 3 0 0 3 3 3 0 Scd6-like Sm domain 7tm_1 PF00001.21 OWF46107.1 - 2.7e-15 56.4 1.8 3.4e-15 56.1 1.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF46107.1 - 2.5e-06 27.0 1.2 3.3e-06 26.6 1.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw FAM176 PF14851.6 OWF46108.1 - 0.059 13.0 2.8 0.093 12.4 2.8 1.3 1 0 0 1 1 1 0 FAM176 family Apolipoprotein PF01442.18 OWF46109.1 - 1e-05 25.5 0.0 1.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OWF46109.1 - 0.0004 20.4 1.5 0.02 14.9 1.5 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 OWF46109.1 - 0.0011 18.4 2.2 0.013 14.9 2.1 2.2 1 1 0 1 1 1 1 SF-assemblin/beta giardin HisKA_3 PF07730.13 OWF46109.1 - 0.0023 18.4 0.5 15 6.2 0.0 3.8 1 1 3 4 4 4 0 Histidine kinase ApoO PF09769.9 OWF46109.1 - 0.0034 17.3 0.5 0.23 11.4 0.5 2.5 1 1 0 1 1 1 1 Apolipoprotein O Amidohydro_1 PF01979.20 OWF46109.1 - 0.0038 16.6 1.3 1.1 8.5 0.2 2.9 1 1 1 2 2 2 2 Amidohydrolase family Prominin PF05478.11 OWF46109.1 - 0.0045 15.0 4.9 0.0063 14.5 4.9 1.3 1 0 0 1 1 1 1 Prominin Phasin PF05597.11 OWF46109.1 - 0.013 15.5 0.2 1.3 9.0 0.1 2.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) COMPASS-Shg1 PF05205.12 OWF46109.1 - 0.056 14.2 5.5 1.8 9.3 0.5 2.3 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 V-SNARE_C PF12352.8 OWF46109.1 - 0.074 13.4 6.7 19 5.7 1.5 3.7 1 1 2 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus ApoLp-III PF07464.11 OWF46109.1 - 0.081 13.0 2.3 0.3 11.2 1.5 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HemX PF04375.14 OWF46109.1 - 0.13 11.5 0.2 8.5 5.6 0.1 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Phasin_2 PF09361.10 OWF46109.1 - 0.18 12.1 0.0 4.6 7.6 0.0 2.3 1 1 1 2 2 2 0 Phasin protein Dynamin_M PF01031.20 OWF46109.1 - 0.45 9.7 6.3 1.2 8.3 6.3 1.7 1 1 0 1 1 1 0 Dynamin central region Fzo_mitofusin PF04799.13 OWF46109.1 - 0.47 10.0 5.7 3 7.4 0.4 2.2 1 1 1 2 2 2 0 fzo-like conserved region Caveolin PF01146.17 OWF46109.1 - 0.93 9.5 6.2 0.57 10.1 1.0 2.1 1 1 1 2 2 2 0 Caveolin HMD PF03201.16 OWF46109.1 - 2.9 8.2 12.2 11 6.3 3.4 3.7 1 1 1 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase UPF0731 PF14982.6 OWF46109.1 - 4.6 7.5 7.3 8 6.7 1.7 2.6 1 1 1 3 3 3 0 UPF0731 family DUF1929 PF09118.11 OWF46110.1 - 0.054 13.8 35.4 1.8e+04 -19.6 35.4 6.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1929) p6 PF17548.2 OWF46110.1 - 0.057 13.4 47.4 1.5 8.9 0.9 8.4 1 1 8 10 10 10 0 Histone-like Protein p6 DUF3927 PF13064.6 OWF46110.1 - 0.5 10.4 6.3 15 5.7 0.1 4.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3927) DUF4655 PF15548.6 OWF46110.1 - 0.64 8.9 2.8 12 4.7 0.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4655) VirArc_Nuclease PF12187.8 OWF46111.1 - 0.045 13.3 21.4 1.5 8.3 0.2 4.8 1 1 3 4 4 4 0 Viral/Archaeal nuclease Ribosomal_L31 PF01197.18 OWF46111.1 - 0.09 13.0 9.4 28 5.0 0.1 5.0 1 1 2 3 3 3 0 Ribosomal protein L31 DUF4767 PF15983.5 OWF46111.1 - 0.22 11.8 4.3 8.9 6.6 1.0 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4767) O_Spanin_T7 PF17531.2 OWF46111.1 - 0.27 11.3 13.1 1.5e+02 2.6 0.0 8.0 2 2 6 9 9 9 0 outer-membrane spanin sub-unit Pox_C7_F8A PF03287.14 OWF46111.1 - 0.95 9.4 20.2 7.1 6.6 0.5 5.4 1 1 5 6 6 6 0 Poxvirus C7/F8A protein Bactofilin PF04519.13 OWF46112.1 - 0.00079 19.7 10.8 0.0023 18.2 10.2 1.9 1 1 0 1 1 1 1 Polymer-forming cytoskeletal p6 PF17548.2 OWF46112.1 - 0.0028 17.6 15.6 1.1 9.3 0.9 4.0 1 1 4 5 5 5 4 Histone-like Protein p6 YscW PF09619.10 OWF46112.1 - 0.082 13.3 8.6 3.1 8.2 5.7 3.7 1 1 1 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) DUF3794 PF12673.7 OWF46112.1 - 0.25 11.6 11.3 6.7 7.1 2.2 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3794) Big_3_5 PF16640.5 OWF46112.1 - 0.53 10.5 9.3 0.33 11.1 2.4 2.3 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) DUF1319 PF07028.11 OWF46112.1 - 4.1 7.7 10.6 4.2 7.6 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF1794 PF08768.11 OWF46114.1 - 0.00024 21.1 3.4 1.9 8.4 0.1 4.5 1 1 1 3 3 3 2 Domain of unknown function (DUF1794) Polyoma_coat PF00718.20 OWF46114.1 - 0.63 9.3 11.5 2.9 7.1 0.1 5.1 1 1 4 6 6 6 0 Polyomavirus coat protein GlgS PF08971.11 OWF46114.1 - 5.8 7.0 0.0 5.8 7.0 0.0 5.6 6 3 2 8 8 8 0 Glycogen synthesis protein Ank_4 PF13637.6 OWF46115.1 - 0.011 16.3 1.0 11 6.7 0.0 4.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) GlgS PF08971.11 OWF46115.1 - 0.06 13.4 1.0 0.6 10.2 0.0 2.9 2 1 2 4 4 4 0 Glycogen synthesis protein ParB_C PF18064.1 OWF46115.1 - 0.087 13.0 1.1 17 5.7 0.1 3.3 1 1 3 4 4 4 0 Centromere-binding protein ParB C-terminal DKCLD PF08068.12 OWF46115.1 - 0.17 12.0 3.7 14 5.9 0.1 3.7 2 1 3 5 5 5 0 DKCLD (NUC011) domain zinc_ribbon_10 PF10058.9 OWF46115.1 - 0.29 10.9 7.2 6.4 6.6 0.1 3.5 3 2 1 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RING_10 PF16685.5 OWF46115.1 - 1.3 9.2 7.0 0.9 9.7 0.4 2.8 2 1 1 3 3 3 0 zinc RING finger of MSL2 ParB_C PF18064.1 OWF46116.1 - 0.073 13.2 2.4 33 4.8 0.0 4.3 4 1 2 6 6 6 0 Centromere-binding protein ParB C-terminal DUF2085 PF09858.9 OWF46116.1 - 5.6 7.5 13.7 55 4.3 0.1 5.0 2 2 3 5 5 5 0 Predicted membrane protein (DUF2085) ParB_C PF18064.1 OWF46117.1 - 0.082 13.1 5.9 7.7 6.8 0.0 4.3 2 1 2 4 4 4 0 Centromere-binding protein ParB C-terminal G8 PF10162.9 OWF46119.1 - 1.3e-20 73.7 0.1 2.6e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 OWF46119.1 - 0.0018 18.1 1.9 0.2 11.5 1.9 3.3 1 1 0 1 1 1 1 Right handed beta helix region ILEI PF15711.5 OWF46119.1 - 0.065 13.7 0.0 0.5 10.9 0.0 2.4 2 0 0 2 2 2 0 Interleukin-like EMT inducer Ank_2 PF12796.7 OWF46120.1 - 6e-12 46.0 0.2 1.4e-06 28.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF46120.1 - 1.1e-10 41.5 0.3 1.2e-06 28.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF46120.1 - 1.4e-10 41.5 0.1 1.1e-07 32.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF46120.1 - 1.2e-09 38.2 0.1 5.7e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OWF46120.1 - 1.8e-09 37.0 0.0 0.00013 22.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DAO PF01266.24 OWF46121.1 - 1.6e-51 176.0 0.0 1.9e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF46121.1 - 6e-05 23.2 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OWF46121.1 - 0.0026 16.7 0.1 0.0051 15.7 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 OWF46121.1 - 0.0052 16.1 0.0 0.0075 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF46121.1 - 0.055 14.0 0.2 0.18 12.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OWF46121.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain EFhand_Ca_insen PF08726.10 OWF46121.1 - 0.08 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand FAD_binding_3 PF01494.19 OWF46121.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Toxin_13 PF07822.11 OWF46121.1 - 0.16 12.1 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein VWA PF00092.28 OWF46122.1 - 3.5e-38 131.6 3.5 6.1e-38 130.8 3.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF46122.1 - 2.3e-12 47.5 1.4 5.1e-12 46.4 1.4 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF46122.1 - 1.6e-11 44.2 27.9 0.00012 22.1 0.2 5.2 4 1 1 5 5 5 4 Chitin binding Peritrophin-A domain Phlebovirus_G1 PF07243.11 OWF46122.1 - 0.0011 17.5 0.7 0.0023 16.4 0.7 1.5 1 0 0 1 1 1 1 Phlebovirus glycoprotein G1 VWA_3 PF13768.6 OWF46122.1 - 0.0016 18.4 0.1 0.0042 17.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 OWF46122.1 - 0.16 11.4 0.3 0.33 10.4 0.3 1.4 1 0 0 1 1 1 0 Copine VWA PF00092.28 OWF46123.1 - 1.7e-42 145.6 2.8 2.9e-42 144.9 2.8 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF46123.1 - 1.5e-16 61.0 0.3 3.8e-16 59.7 0.3 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF46123.1 - 1.8e-09 37.6 12.4 0.0095 16.1 0.1 4.0 4 0 0 4 4 4 3 Chitin binding Peritrophin-A domain VWA_3 PF13768.6 OWF46123.1 - 2.6e-06 27.5 0.1 4.3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 OWF46123.1 - 0.0021 17.3 1.2 0.0035 16.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 OWF46123.1 - 0.0029 17.0 0.1 0.0046 16.4 0.1 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Copine PF07002.16 OWF46123.1 - 0.028 13.9 0.3 0.051 13.0 0.3 1.4 1 0 0 1 1 1 0 Copine Mtf2_C PF14061.6 OWF46124.1 - 1.2e-18 67.0 0.0 2.6e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD PF00628.29 OWF46124.1 - 3.2e-13 49.3 33.9 9.9e-10 38.2 13.3 2.6 2 0 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 OWF46124.1 - 8.4e-12 44.6 0.1 1.6e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Prok-RING_1 PF14446.6 OWF46124.1 - 0.00054 19.8 6.3 0.00054 19.8 6.3 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 LBR_tudor PF09465.10 OWF46124.1 - 0.0015 18.3 0.2 0.0035 17.1 0.2 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 OWF46124.1 - 0.0021 18.1 0.0 0.0058 16.7 0.0 1.7 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor-knot PF11717.8 OWF46124.1 - 0.0038 17.1 0.3 0.019 14.9 0.0 2.3 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain C1_1 PF00130.22 OWF46124.1 - 0.0053 16.6 2.8 0.0053 16.6 2.8 3.3 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4537 PF15057.6 OWF46124.1 - 0.0056 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 OWF46124.1 - 0.072 13.1 0.2 0.21 11.6 0.2 1.8 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Neur_chan_memb PF02932.16 OWF46125.1 - 6.9e-11 42.7 0.8 8.7e-11 42.3 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ABC2_membrane_5 PF13346.6 OWF46125.1 - 0.025 14.1 10.7 0.034 13.7 10.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ank_2 PF12796.7 OWF46126.1 - 2.2e-62 207.6 26.3 9.4e-16 58.2 0.6 8.8 4 1 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF46126.1 - 2.2e-48 162.0 21.2 5.3e-06 26.9 0.0 12.1 7 4 6 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46126.1 - 5.9e-45 146.1 10.8 0.002 18.4 0.0 16.2 17 0 0 17 17 16 8 Ankyrin repeat Ank_5 PF13857.6 OWF46126.1 - 5.8e-41 138.0 22.4 6.9e-08 32.6 0.0 11.1 9 2 2 11 11 10 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF46126.1 - 9.3e-36 120.7 21.0 0.0053 17.2 0.0 14.7 14 0 0 14 14 14 8 Ankyrin repeat Ion_trans PF00520.31 OWF46126.1 - 3.2e-08 33.1 23.7 1.5e-07 30.9 23.8 1.9 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OWF46126.1 - 1.3e-07 30.7 9.3 2.5e-07 29.7 9.3 1.4 1 0 0 1 1 1 1 Polycystin cation channel BLOC1_2 PF10046.9 OWF46126.1 - 0.002 18.4 3.7 0.0062 16.8 3.7 1.8 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 OWF46126.1 - 0.0062 17.0 2.3 0.021 15.2 2.3 1.9 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CCDC53 PF10152.9 OWF46126.1 - 0.03 14.7 3.2 0.1 13.0 3.2 1.9 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Laminin_II PF06009.12 OWF46126.1 - 0.042 13.9 5.1 0.082 12.9 3.9 2.1 2 0 0 2 2 1 0 Laminin Domain II Fib_alpha PF08702.10 OWF46126.1 - 0.05 13.8 4.0 0.16 12.1 4.0 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 OWF46126.1 - 0.086 12.8 0.8 0.21 11.5 0.8 1.6 1 0 0 1 1 1 0 Apolipoprotein O MIP-T3_C PF17749.1 OWF46126.1 - 0.15 12.0 5.2 0.39 10.7 5.2 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Com_YlbF PF06133.11 OWF46126.1 - 0.18 12.4 4.0 0.26 11.9 1.9 2.5 2 0 0 2 2 1 0 Control of competence regulator ComK, YlbF/YmcA DUF4988 PF16378.5 OWF46126.1 - 0.19 11.4 5.4 0.81 9.3 2.7 2.7 3 0 0 3 3 2 0 Domain of unknown function FlaC_arch PF05377.11 OWF46126.1 - 0.21 12.0 5.1 0.76 10.2 5.1 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 OWF46126.1 - 0.22 11.7 4.8 0.92 9.8 4.8 2.1 1 0 0 1 1 1 0 Haemolysin XhlA PAP2 PF01569.21 OWF46126.1 - 0.55 10.0 5.6 0.56 10.0 0.8 2.6 2 0 0 2 2 2 0 PAP2 superfamily DUF948 PF06103.11 OWF46126.1 - 8.8 6.7 12.5 0.63 10.3 5.5 2.8 3 0 0 3 3 1 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.32 OWF46127.1 - 1.1e-28 98.8 6.6 1.6e-08 35.1 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 OWF46127.1 - 1.4e-09 37.2 0.3 0.0014 17.3 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OWF46127.1 - 3e-09 37.1 0.3 0.0001 22.5 0.0 4.5 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF46127.1 - 0.002 17.5 0.2 0.86 8.9 0.0 2.5 3 0 0 3 3 3 2 WD40-like domain TPR_12 PF13424.6 OWF46128.1 - 4.5e-37 126.2 29.5 3.3e-11 43.3 0.3 5.4 4 1 1 5 5 5 5 Tetratricopeptide repeat GoLoco PF02188.17 OWF46128.1 - 5.6e-32 108.8 20.8 6e-10 38.4 2.7 4.4 4 0 0 4 4 4 4 GoLoco motif TPR_1 PF00515.28 OWF46128.1 - 4e-31 105.5 33.8 1.6e-05 24.5 0.2 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46128.1 - 4.7e-31 104.5 20.3 6.8e-05 22.6 0.1 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 OWF46128.1 - 7.7e-20 69.4 28.5 0.002 18.1 0.3 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46128.1 - 1.2e-16 59.4 26.1 0.016 15.4 0.2 8.2 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46128.1 - 1.6e-14 53.2 26.0 0.0023 17.7 0.2 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat Rapsyn_N PF10579.9 OWF46128.1 - 2.6e-08 33.8 1.1 0.033 14.3 0.0 4.2 4 1 1 5 5 5 3 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.6 OWF46128.1 - 3.6e-07 30.7 10.9 0.018 15.7 0.1 5.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF46128.1 - 3.4e-06 26.7 5.7 0.0011 18.5 1.1 3.0 2 1 1 3 3 3 2 MalT-like TPR region TPR_11 PF13414.6 OWF46128.1 - 2.2e-05 24.0 19.6 0.1 12.3 0.3 7.4 7 1 1 8 8 8 1 TPR repeat TPR_4 PF07721.14 OWF46128.1 - 2.7e-05 24.4 1.6 2.3 9.1 0.1 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46128.1 - 0.00016 22.2 6.1 26 6.0 0.1 7.2 7 2 2 9 9 7 0 Tetratricopeptide repeat UreE_C PF05194.12 OWF46128.1 - 0.034 14.6 0.9 4.1 8.0 0.0 3.4 3 1 1 4 4 3 0 UreE urease accessory protein, C-terminal domain ANAPC5 PF12862.7 OWF46128.1 - 0.047 13.8 2.5 33 4.6 0.0 4.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 5 AP_endonuc_2 PF01261.24 OWF46128.1 - 0.061 12.7 0.5 1.1 8.7 0.5 2.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel GCK PF07802.11 OWF46128.1 - 0.074 13.5 0.3 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 GCK domain NRBF2_MIT PF17169.4 OWF46128.1 - 0.076 13.2 0.4 11 6.3 0.0 3.3 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 TPR_17 PF13431.6 OWF46128.1 - 0.12 12.8 11.1 12 6.6 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 OWF46128.1 - 0.27 10.9 2.8 10 5.8 0.1 3.6 2 2 2 5 5 5 0 26S proteasome subunit RPN7 TPR_14 PF13428.6 OWF46129.1 - 1.1e-17 63.2 8.8 0.55 11.2 0.0 11.2 9 3 3 12 12 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46129.1 - 4.1e-12 46.4 1.6 0.01 16.3 0.0 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 OWF46129.1 - 7.3e-11 42.6 16.0 0.0055 16.7 0.5 5.7 4 1 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_2 PF07719.17 OWF46129.1 - 3.1e-10 39.4 15.2 0.047 13.8 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46129.1 - 1.6e-09 37.2 7.3 0.96 9.8 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF46129.1 - 1.9e-09 37.7 2.1 0.43 10.9 0.0 6.3 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 OWF46129.1 - 1.7e-05 24.2 0.3 2.2 7.4 0.0 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF46129.1 - 0.00028 21.3 5.5 11 6.9 0.0 6.9 6 1 1 7 7 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 OWF46129.1 - 0.00078 18.7 15.9 0.16 11.0 1.9 6.7 3 3 1 5 5 5 2 NRDE-2, necessary for RNA interference MIT PF04212.18 OWF46129.1 - 0.001 19.1 0.1 4.5 7.4 0.2 5.1 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain PPR PF01535.20 OWF46129.1 - 0.0025 18.0 3.9 0.14 12.4 0.0 5.3 5 0 0 5 5 5 1 PPR repeat TPR_7 PF13176.6 OWF46129.1 - 0.0029 17.5 0.8 0.83 9.8 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OWF46129.1 - 0.0031 17.5 15.1 5.5 7.0 0.0 6.6 6 3 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 OWF46129.1 - 0.0034 17.7 4.5 54 4.5 0.0 6.9 8 1 0 8 8 6 0 Tetratricopeptide repeat BDHCT_assoc PF16204.5 OWF46129.1 - 0.03 14.0 0.7 0.049 13.3 0.7 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Phage_Cox PF10743.9 OWF46129.1 - 0.14 12.3 0.2 8.2 6.6 0.0 3.0 1 1 1 2 2 2 0 Regulatory phage protein cox PPR_2 PF13041.6 OWF46129.1 - 0.2 11.9 4.1 3.7 7.8 0.0 4.6 6 0 0 6 6 6 0 PPR repeat family TPR_16 PF13432.6 OWF46129.1 - 0.63 10.7 7.9 28 5.4 0.0 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46129.1 - 1.8 8.5 16.2 13 5.8 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat HAT PF02184.16 OWF46129.1 - 5.8 7.0 17.1 23 5.1 0.0 7.2 9 0 0 9 9 9 0 HAT (Half-A-TPR) repeat Cu2_monoox_C PF03712.15 OWF46130.1 - 8.9e-27 93.5 0.7 1.7e-26 92.6 0.7 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF46130.1 - 2.7e-24 85.9 0.2 5.9e-24 84.8 0.2 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain EF-hand_7 PF13499.6 OWF46131.1 - 3.7e-07 30.5 9.6 0.041 14.3 0.1 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF46131.1 - 1.1e-06 27.8 13.3 0.00045 19.6 1.0 4.4 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 OWF46131.1 - 1.1e-05 24.9 9.8 0.035 14.1 0.8 4.1 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OWF46131.1 - 4.5e-05 22.7 8.4 0.033 13.8 0.4 4.1 3 1 1 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 OWF46131.1 - 0.00013 22.2 1.0 2.1 8.7 0.1 3.3 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pan3_PK PF18101.1 OWF46131.1 - 0.097 12.6 0.4 4.5 7.2 0.0 2.1 1 1 1 2 2 2 0 Pan3 Pseudokinase domain EF-hand_1 PF00036.32 OWF46132.1 - 2.6e-07 29.7 8.3 0.014 14.9 0.2 4.2 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF46132.1 - 1.1e-06 28.0 6.6 0.014 15.2 0.3 4.2 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OWF46132.1 - 3.5e-06 27.4 6.6 0.032 14.7 0.2 4.0 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF46132.1 - 0.00055 19.3 11.1 0.018 14.5 0.2 4.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 OWF46132.1 - 0.11 12.4 5.3 0.51 10.2 0.2 3.5 4 0 0 4 4 4 0 EF-hand domain pair DUF4766 PF15973.5 OWF46133.1 - 2.2 8.9 21.6 0.44 11.1 16.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4766) KRTAP PF11759.8 OWF46134.1 - 5.5 7.6 34.6 0.082 13.5 25.9 2.1 2 0 0 2 2 2 0 Keratin-associated matrix KRTAP PF11759.8 OWF46135.1 - 0.015 15.9 24.3 0.015 15.9 24.3 2.0 2 0 0 2 2 2 0 Keratin-associated matrix Choline_transpo PF04515.12 OWF46136.1 - 4.9e-92 308.6 42.6 4.9e-92 308.6 42.6 3.1 3 1 0 3 3 3 1 Plasma-membrane choline transporter Choline_transpo PF04515.12 OWF46137.1 - 5.4e-106 354.5 32.8 5.4e-106 354.5 32.8 3.0 3 1 0 3 3 3 1 Plasma-membrane choline transporter Choline_transpo PF04515.12 OWF46138.1 - 6.8e-100 334.4 29.4 6.8e-100 334.4 29.4 3.2 3 0 0 3 3 3 1 Plasma-membrane choline transporter Picorna_P3A PF06363.11 OWF46138.1 - 0.024 14.5 0.7 1.6 8.7 0.1 3.0 2 0 0 2 2 2 0 Picornaviridae P3A protein Choline_transpo PF04515.12 OWF46139.1 - 7e-101 337.7 33.1 7e-101 337.7 33.1 3.4 3 1 1 4 4 4 1 Plasma-membrane choline transporter 7tm_1 PF00001.21 OWF46140.1 - 5.8e-30 104.5 35.9 7.4e-30 104.1 35.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF46140.1 - 0.00022 20.7 36.4 0.0003 20.3 36.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF46144.1 - 1.6e-28 99.7 3.6 2e-28 99.4 3.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF46144.1 - 8.7e-06 25.2 10.6 0.0066 15.8 3.6 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Shisa PF13908.6 OWF46144.1 - 0.055 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CHD5 PF04420.14 OWF46144.1 - 0.074 12.9 1.4 0.22 11.4 0.2 2.1 2 0 0 2 2 2 0 CHD5-like protein DUF4834 PF16118.5 OWF46144.1 - 0.87 10.6 4.4 7.5 7.6 4.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Methyltransf_21 PF05050.12 OWF46145.1 - 0.00037 20.6 0.1 0.00046 20.2 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Codanin-1_C PF15296.6 OWF46147.1 - 3.7e-33 114.1 0.1 3.7e-33 114.1 0.1 2.4 2 1 0 2 2 2 1 Codanin-1 C-terminus DUF2730 PF10805.8 OWF46147.1 - 0.11 12.6 0.3 0.34 11.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) BTB PF00651.31 OWF46148.1 - 8.2e-16 58.2 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF948 PF06103.11 OWF46148.1 - 0.029 14.6 1.9 0.056 13.7 1.9 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CutA1 PF03091.15 OWF46149.1 - 0.12 12.3 0.1 0.41 10.5 0.1 1.8 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Cactin_mid PF10312.9 OWF46150.1 - 3.4e-64 216.2 5.6 3.4e-64 216.2 5.6 2.4 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OWF46150.1 - 7.7e-57 190.6 11.3 1.6e-56 189.6 11.3 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein LINES_C PF14695.6 OWF46151.1 - 6.1e-08 32.0 0.1 1.3e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Lines C-terminus HLH PF00010.26 OWF46151.1 - 0.039 13.9 0.1 0.098 12.6 0.1 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF1589 PF07628.11 OWF46151.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) TRM PF02005.16 OWF46152.1 - 4.3e-128 427.7 1.4 5.4e-128 427.4 1.4 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OWF46152.1 - 2.1e-05 24.4 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 OWF46152.1 - 0.0004 20.1 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 OWF46152.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.13 OWF46152.1 - 0.023 14.1 1.0 0.045 13.1 0.0 2.0 3 0 0 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 OWF46153.1 - 5e-126 420.9 0.7 6.4e-126 420.5 0.7 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OWF46153.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 OWF46153.1 - 0.00048 19.8 0.0 0.00099 18.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 OWF46153.1 - 0.0005 19.6 0.3 0.0012 18.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 OWF46153.1 - 0.034 13.8 0.9 0.43 10.2 0.0 2.9 3 1 1 4 4 4 0 16S rRNA methyltransferase RsmB/F Methyltransf_3 PF01596.17 OWF46153.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase IQ PF00612.27 OWF46154.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Swi3 PF07962.12 OWF46155.1 - 6.8e-31 106.1 0.1 1.5e-30 105.0 0.0 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 GREB1 PF15782.5 OWF46155.1 - 0.014 12.6 9.2 0.019 12.2 9.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PH_5 PF15405.6 OWF46155.1 - 0.72 10.0 2.8 80 3.3 0.0 3.4 3 0 0 3 3 3 0 Pleckstrin homology domain ubiquitin PF00240.23 OWF46156.1 - 3.2e-08 33.2 0.1 7.4e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OWF46156.1 - 3e-07 30.2 0.5 6.9e-07 29.1 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 OWF46156.1 - 0.00079 19.2 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Ubiquitin_5 PF18037.1 OWF46156.1 - 0.0012 19.2 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OWF46156.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 OWF46156.1 - 0.029 14.4 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair Trp_ring PF18669.1 OWF46157.1 - 2.7e-06 27.4 9.7 7.7 6.8 0.1 8.1 1 1 6 9 9 9 1 Trimeric autotransporter adhesin Trp ring domain Galactosyl_T PF01762.21 OWF46157.1 - 7e-06 26.0 6.4 4.3 7.1 0.0 5.3 1 1 6 7 7 7 1 Galactosyltransferase DUF5001 PF16392.5 OWF46157.1 - 3e-05 23.8 5.7 6.7 6.7 0.0 5.9 1 1 5 6 6 6 1 Ig-like domain DUF4975 PF16346.5 OWF46157.1 - 4.8e-05 23.5 8.0 6 6.9 0.1 5.0 1 1 3 5 5 5 1 Domain of unknown function (DUF4975) Cpn10 PF00166.21 OWF46157.1 - 9.8e-05 22.3 6.0 4.7 7.4 0.2 5.8 1 1 5 6 6 6 1 Chaperonin 10 Kd subunit SAS-6_N PF16531.5 OWF46157.1 - 0.00018 22.0 0.0 33 5.1 0.0 4.6 2 1 1 4 4 4 0 Centriolar protein SAS N-terminal Invas_SpaK PF03519.14 OWF46157.1 - 0.00067 19.7 21.5 5.9 7.0 0.1 6.6 1 1 7 8 8 8 1 Invasion protein B family DUF2715 PF10895.8 OWF46157.1 - 0.0025 17.4 19.7 51 3.4 19.7 3.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) FRG1 PF06229.12 OWF46157.1 - 0.0031 17.2 2.3 1.8 8.3 0.0 4.3 1 1 4 5 5 5 1 FRG1-like domain Ribosomal_L28e PF01778.17 OWF46157.1 - 0.0041 17.9 2.0 28 5.5 0.0 4.3 1 1 3 4 4 4 0 Ribosomal L28e protein family DUF4988 PF16378.5 OWF46157.1 - 0.0043 16.7 8.2 0.15 11.7 0.9 2.7 1 1 1 2 2 2 2 Domain of unknown function PAS_12 PF18095.1 OWF46157.1 - 0.0079 15.8 8.1 40 3.8 0.1 5.8 1 1 4 6 6 6 0 UPF0242 C-terminal PAS-like domain HATPase_c PF02518.26 OWF46157.1 - 0.03 14.8 24.3 1.3e+02 3.1 7.5 5.3 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RsgI_N PF12791.7 OWF46157.1 - 0.044 13.7 4.6 29 4.7 0.1 4.0 4 0 0 4 4 4 0 Anti-sigma factor N-terminus PH_15 PF17339.2 OWF46157.1 - 0.1 12.5 14.5 14 5.6 0.5 5.2 1 1 4 5 5 5 0 PH domain DUF3843 PF12954.7 OWF46157.1 - 0.16 10.9 11.6 5.6 5.8 0.2 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF3843) Apocytochr_F_C PF01333.19 OWF46157.1 - 0.18 11.8 14.1 18 5.4 2.0 5.2 1 1 3 4 4 4 0 Apocytochrome F, C-terminal PA_decarbox PF05870.11 OWF46157.1 - 0.38 10.4 9.8 8.9 5.9 0.2 4.0 2 1 3 5 5 5 0 Phenolic acid decarboxylase (PAD) NPL PF17800.1 OWF46157.1 - 0.5 11.0 10.9 1.3e+02 3.2 0.1 6.6 1 1 1 3 3 3 0 Nucleoplasmin-like domain NTNH_C PF08470.10 OWF46157.1 - 0.64 9.9 2.1 45 3.9 0.0 3.5 1 1 1 3 3 3 0 Nontoxic nonhaemagglutinin C-terminal GatD_N PF18195.1 OWF46157.1 - 1.1 8.7 21.1 4.7 6.6 0.4 6.3 1 1 6 7 7 7 0 GatD N-terminal domain CUB_2 PF02408.20 OWF46157.1 - 1.2 8.9 3.8 1.2e+02 2.5 0.0 4.1 1 1 6 7 7 7 0 CUB-like domain PRORP PF16953.5 OWF46157.1 - 7.9 5.9 7.8 38 3.7 0.1 3.7 1 1 1 4 4 4 0 Protein-only RNase P DUF2170 PF09938.9 OWF46158.1 - 2.2e-07 30.6 1.1 2 8.1 0.0 4.6 1 1 2 4 4 4 3 Uncharacterized protein conserved in bacteria (DUF2170) T6SS_Vgr PF13296.6 OWF46158.1 - 3.2e-05 24.0 2.4 18 5.5 0.0 5.5 1 1 5 6 6 6 0 Putative type VI secretion system Rhs element Vgr DUF5001 PF16392.5 OWF46158.1 - 3.5e-05 23.6 3.6 1.3 9.0 0.0 4.6 1 1 3 4 4 4 1 Ig-like domain FRG1 PF06229.12 OWF46158.1 - 0.0011 18.7 0.7 0.71 9.6 0.0 3.2 2 1 0 3 3 3 1 FRG1-like domain Cpn10 PF00166.21 OWF46158.1 - 0.0013 18.7 3.3 0.41 10.8 0.2 4.1 1 1 0 2 2 2 1 Chaperonin 10 Kd subunit SRX PF09201.10 OWF46158.1 - 0.02 14.7 0.0 9.9 6.0 0.0 3.1 1 1 3 4 4 4 0 SRX, signal recognition particle receptor alpha subunit RE_AccI PF09545.10 OWF46158.1 - 0.026 13.5 19.9 2.2 7.2 0.9 4.1 1 1 2 4 4 4 0 AccI restriction endonuclease Apocytochr_F_C PF01333.19 OWF46158.1 - 0.055 13.5 10.8 11 6.1 0.2 4.1 1 1 3 4 4 4 0 Apocytochrome F, C-terminal Sec_GG PF07549.14 OWF46158.1 - 0.087 12.3 0.0 25 4.5 0.0 5.2 7 2 1 8 8 8 0 SecD/SecF GG Motif HATPase_c PF02518.26 OWF46158.1 - 0.68 10.5 17.5 1.8e+04 -6.1 17.5 4.7 1 1 0 1 1 0 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PH_15 PF17339.2 OWF46158.1 - 8.3 6.4 11.9 29 4.6 0.4 4.0 1 1 3 4 4 4 0 PH domain Plasmod_dom_1 PF09715.10 OWF46158.1 - 8.5 6.5 9.9 22 5.2 0.2 3.7 3 2 2 5 5 5 0 Plasmodium protein of unknown function (Plasmod_dom_1) Sec_GG PF07549.14 OWF46159.1 - 3e-07 29.7 0.0 91 2.8 0.0 10.0 5 2 9 14 14 14 0 SecD/SecF GG Motif DUF4975 PF16346.5 OWF46159.1 - 7.9e-07 29.3 2.3 1.5 8.9 0.1 4.2 1 1 3 5 5 5 4 Domain of unknown function (DUF4975) DUF5001 PF16392.5 OWF46159.1 - 0.0011 18.8 0.5 8.3 6.4 0.0 3.9 1 1 1 2 2 2 2 Ig-like domain Alpha_adaptinC2 PF02883.20 OWF46159.1 - 0.0019 18.5 2.6 3.9 7.8 2.6 4.6 1 1 0 1 1 1 1 Adaptin C-terminal domain DUF2715 PF10895.8 OWF46159.1 - 0.012 15.3 8.3 0.24 11.0 8.3 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) DUF3332 PF11810.8 OWF46159.1 - 0.026 14.1 1.6 0.23 11.1 1.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) Galactosyl_T PF01762.21 OWF46159.1 - 0.028 14.3 1.7 17 5.1 0.1 3.3 1 1 3 4 4 4 0 Galactosyltransferase Fascin PF06268.13 OWF46159.1 - 0.034 14.4 0.0 1.6 9.0 0.0 2.3 1 1 1 2 2 2 0 Fascin domain PA_decarbox PF05870.11 OWF46159.1 - 0.042 13.5 1.1 0.52 9.9 0.2 2.3 1 1 0 2 2 2 0 Phenolic acid decarboxylase (PAD) Apocytochr_F_C PF01333.19 OWF46159.1 - 0.044 13.8 6.8 6.5 6.8 0.4 3.5 1 1 3 4 4 4 0 Apocytochrome F, C-terminal G6PD_C PF02781.16 OWF46159.1 - 0.098 11.8 1.1 6 6.0 1.1 2.7 1 1 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain VEG PF06257.11 OWF46159.1 - 0.13 12.3 7.1 2.1 8.4 0.3 4.7 1 1 4 5 5 5 0 Biofilm formation stimulator VEG Fmp27_GFWDK PF10347.9 OWF46159.1 - 0.82 9.8 4.9 30 4.7 0.1 4.0 2 1 4 6 6 6 0 RNA pol II promoter Fmp27 protein domain Bromo_coat PF01318.18 OWF46159.1 - 3.8 7.5 9.0 8.9 6.4 0.3 3.2 1 1 1 3 3 3 0 Bromovirus coat protein DUF4975 PF16346.5 OWF46160.1 - 0.0011 19.1 0.9 0.37 10.8 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4975) T6SS_Vgr PF13296.6 OWF46160.1 - 0.0022 18.1 0.3 5.3 7.2 0.1 3.5 1 1 2 3 3 3 1 Putative type VI secretion system Rhs element Vgr DUF2170 PF09938.9 OWF46160.1 - 0.0054 16.4 0.7 4.5 7.0 0.0 3.1 1 1 3 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2170) TFX_C PF14601.6 OWF46160.1 - 0.031 14.2 2.0 3.2 7.8 0.1 2.1 1 1 1 2 2 2 0 DNA_binding protein, TFX, C-term Pallilysin PF18663.1 OWF46160.1 - 0.038 14.0 2.4 0.49 10.4 0.2 2.2 1 1 1 2 2 2 0 Pallilysin beta barrel domain Alpha_adaptinC2 PF02883.20 OWF46160.1 - 0.065 13.5 2.6 3.2 8.1 0.2 2.6 1 1 1 3 3 3 0 Adaptin C-terminal domain Invas_SpaK PF03519.14 OWF46160.1 - 0.12 12.4 4.8 5.3 7.2 3.6 2.9 1 1 1 2 2 2 0 Invasion protein B family PulG PF11773.8 OWF46160.1 - 0.18 11.6 6.4 8.1 6.4 0.4 3.3 3 1 0 3 3 3 0 Type II secretory pathway pseudopilin ID PF18543.1 OWF46160.1 - 0.23 11.5 4.8 7 6.8 0.5 2.6 1 1 0 2 2 2 0 Intracellular delivery domain UreD PF01774.17 OWF46160.1 - 0.29 11.0 1.3 9.4 6.1 0.2 2.0 1 1 1 2 2 2 0 UreD urease accessory protein Pilin PF00114.19 OWF46160.1 - 4.3 8.3 8.3 19 6.2 1.4 2.3 1 1 1 2 2 2 0 Pilin (bacterial filament) DUF2715 PF10895.8 OWF46161.1 - 0.00023 20.8 10.5 0.0063 16.2 10.5 3.2 1 1 0 1 1 1 1 Domain of unknown function (DUF2715) DUF5001 PF16392.5 OWF46161.1 - 0.00068 19.5 0.3 2.2 8.2 0.0 3.7 1 1 2 3 3 3 2 Ig-like domain PH_15 PF17339.2 OWF46161.1 - 0.01 15.7 2.1 6.1 6.8 0.2 3.3 1 1 2 3 3 3 0 PH domain Invas_SpaK PF03519.14 OWF46161.1 - 0.018 15.1 17.5 9.4 6.4 0.1 5.6 1 1 6 7 7 7 0 Invasion protein B family T6SS_Vgr PF13296.6 OWF46161.1 - 0.023 14.9 1.4 17 5.6 0.1 4.4 1 1 2 3 3 3 0 Putative type VI secretion system Rhs element Vgr Cupredoxin_1 PF13473.6 OWF46161.1 - 0.043 13.9 0.8 16 5.6 0.0 3.1 2 2 0 2 2 2 0 Cupredoxin-like domain DUF1943 PF09172.11 OWF46161.1 - 2.1 7.5 9.0 2.1 7.5 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) PH_15 PF17339.2 OWF46162.1 - 0.00069 19.5 1.6 0.069 13.0 0.1 2.1 1 1 1 2 2 2 2 PH domain DUF4361 PF14274.6 OWF46162.1 - 0.0018 18.6 3.6 0.5 10.7 0.7 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4361) DUF4975 PF16346.5 OWF46162.1 - 0.01 15.9 0.3 0.053 13.6 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4975) zf-UBP_var PF17807.1 OWF46162.1 - 0.025 14.3 0.1 0.49 10.2 0.1 2.8 1 1 1 2 2 2 0 Variant UBP zinc finger DUF2715 PF10895.8 OWF46162.1 - 0.052 13.2 2.9 0.15 11.7 2.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) Invas_SpaK PF03519.14 OWF46162.1 - 0.058 13.5 4.6 0.97 9.5 0.8 2.9 1 1 2 3 3 3 0 Invasion protein B family DUF5001 PF16392.5 OWF46162.1 - 0.11 12.4 0.1 1.9 8.4 0.1 2.5 1 1 1 2 2 2 0 Ig-like domain NPL PF17800.1 OWF46162.1 - 0.19 12.3 2.6 43 4.7 0.1 3.3 1 1 2 3 3 3 0 Nucleoplasmin-like domain YmgD PF16456.5 OWF46163.1 - 0.002 18.1 3.8 0.64 10.1 0.5 2.7 1 1 1 2 2 2 2 YmgD protein CAAP1 PF15335.6 OWF46163.1 - 0.0097 16.4 15.5 5.1 7.7 0.4 4.1 1 1 1 4 4 4 4 Caspase activity and apoptosis inhibitor 1 SpoU_sub_bind PF08032.12 OWF46163.1 - 0.014 15.6 0.1 45 4.4 0.0 4.3 2 2 4 6 6 6 0 RNA 2'-O ribose methyltransferase substrate binding DUF4806 PF16064.5 OWF46163.1 - 0.12 12.7 0.0 24 5.3 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4806) CTP_synth_N PF06418.14 OWF46163.1 - 1.4 8.1 7.2 7.1 5.9 0.9 2.1 1 1 1 2 2 2 0 CTP synthase N-terminus PEX-1N PF09262.11 OWF46163.1 - 2.2 8.8 8.1 5.7 7.4 1.0 2.2 1 1 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal NHL PF01436.21 OWF46164.1 - 0.018 15.1 1.5 5.9 7.1 0.0 3.4 3 0 0 3 3 3 0 NHL repeat PQQ_2 PF13360.6 OWF46164.1 - 0.052 13.1 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain Plasmodium_HRP PF05403.11 OWF46165.1 - 0.0059 16.4 13.1 0.037 13.8 13.1 1.9 1 1 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) ETF_alpha PF00766.19 OWF46165.1 - 0.28 11.3 8.6 29 4.8 0.2 4.3 1 1 4 5 5 5 0 Electron transfer flavoprotein FAD-binding domain 7tm_1 PF00001.21 OWF46166.1 - 2.1e-41 142.0 11.0 2.6e-41 141.7 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF46166.1 - 0.00021 20.7 10.0 0.00044 19.7 10.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx HSR PF03172.13 OWF46167.1 - 0.0012 18.9 0.3 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 HSR domain CARD_2 PF16739.5 OWF46167.1 - 0.0036 17.3 0.1 0.013 15.5 0.1 2.0 1 0 0 1 1 1 1 Caspase recruitment domain FR47 PF08445.10 OWF46167.1 - 0.076 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein AAA_23 PF13476.6 OWF46168.1 - 2.6e-21 77.1 5.1 2.6e-21 77.1 5.1 5.2 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.19 OWF46168.1 - 5.2e-15 55.5 26.8 1.9e-14 53.7 26.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OWF46168.1 - 3.9e-07 30.1 16.3 3.9e-07 30.1 16.3 3.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OWF46168.1 - 0.00021 21.2 20.5 0.00075 19.4 0.1 4.0 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OWF46168.1 - 0.00087 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.9 OWF46168.1 - 0.036 14.4 53.8 0.06 13.7 0.6 7.9 5 2 4 9 9 9 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RsgA_GTPase PF03193.16 OWF46168.1 - 0.22 11.4 0.0 0.22 11.4 0.0 3.5 4 1 1 5 5 5 0 RsgA GTPase AAA PF00004.29 OWF46168.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Ion_trans PF00520.31 OWF46169.1 - 2.3e-06 27.0 5.7 2.9e-06 26.7 5.7 1.1 1 0 0 1 1 1 1 Ion transport protein NEMP PF10225.9 OWF46169.1 - 0.023 14.4 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 NEMP family MAM PF00629.23 OWF46170.1 - 3.6e-64 215.5 0.1 4e-32 111.4 0.1 2.1 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Ion_trans PF00520.31 OWF46171.1 - 6.9e-07 28.7 0.6 6.9e-07 28.7 0.6 1.4 2 0 0 2 2 2 1 Ion transport protein Tropomyosin PF00261.20 OWF46171.1 - 0.00096 18.6 4.5 0.0019 17.6 4.5 1.4 1 0 0 1 1 1 1 Tropomyosin HAUS5 PF14817.6 OWF46171.1 - 0.0065 15.3 0.3 0.0093 14.8 0.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Prefoldin_2 PF01920.20 OWF46171.1 - 0.013 15.4 2.7 0.013 15.4 2.7 1.8 2 0 0 2 2 2 0 Prefoldin subunit RT_RNaseH_2 PF17919.1 OWF46171.1 - 0.016 15.2 0.7 0.028 14.5 0.1 1.7 2 0 0 2 2 1 0 RNase H-like domain found in reverse transcriptase DUF4094 PF13334.6 OWF46171.1 - 0.021 15.2 0.5 0.021 15.2 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) HR1 PF02185.16 OWF46171.1 - 0.045 13.9 2.1 0.045 13.9 2.1 1.7 2 0 0 2 2 2 0 Hr1 repeat CLZ PF16526.5 OWF46171.1 - 0.077 13.4 3.5 0.28 11.6 3.5 1.9 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mto2_bdg PF12808.7 OWF46171.1 - 0.099 13.0 6.3 0.14 12.5 3.3 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1664 PF07889.12 OWF46171.1 - 0.11 12.5 1.3 0.29 11.2 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 OWF46171.1 - 0.11 12.9 1.8 0.3 11.6 1.8 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.6 OWF46171.1 - 0.12 12.7 6.7 0.51 10.7 3.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF5320 PF17253.2 OWF46171.1 - 0.18 12.9 0.2 0.18 12.9 0.2 1.6 2 0 0 2 2 1 0 Family of unknown function (DUF5320) DUF4200 PF13863.6 OWF46171.1 - 0.32 11.4 11.3 0.047 14.1 7.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.15 OWF46171.1 - 1.1 9.1 5.1 3.1 7.6 5.1 1.8 1 0 0 1 1 1 0 Septum formation initiator Spc24 PF08286.11 OWF46171.1 - 3.3 8.0 6.7 1.2 9.5 1.8 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Lipase_GDSL_2 PF13472.6 OWF46172.1 - 1.7e-08 35.0 0.0 2.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF46172.1 - 2e-08 34.5 0.0 2.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALS_ss_C PF10369.9 OWF46172.1 - 0.082 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Small subunit of acetolactate synthase DUF725 PF05267.12 OWF46172.1 - 0.094 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) T2SSF PF00482.23 OWF46172.1 - 0.16 12.0 0.0 0.86 9.6 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F SPRY PF00622.28 OWF46173.1 - 2.5e-20 72.8 0.1 4.1e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 OWF46173.1 - 4.5e-06 26.9 0.2 7.1e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 SOCS box LRR_9 PF14580.6 OWF46174.1 - 2.8e-90 300.5 3.0 3.9e-90 300.0 3.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OWF46174.1 - 2.5e-06 27.1 5.0 1.4e-05 24.7 4.4 2.4 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 OWF46174.1 - 1.9e-05 24.9 12.9 0.0096 16.3 4.7 3.7 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) Adaptin_N PF01602.20 OWF46175.1 - 3.9e-139 464.6 13.3 5.7e-139 464.0 13.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region AP3D1 PF06375.11 OWF46175.1 - 5e-32 111.3 14.8 5e-32 111.3 14.8 3.4 2 1 0 3 3 3 2 AP-3 complex subunit delta-1 Cnd1 PF12717.7 OWF46175.1 - 3.6e-14 53.1 4.0 2.2e-10 40.8 0.0 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OWF46175.1 - 1.7e-05 25.1 0.1 0.34 11.3 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 OWF46175.1 - 7.9e-05 22.6 0.3 2 8.9 0.1 4.1 5 0 0 5 5 3 2 HEAT repeat RTP1_C1 PF10363.9 OWF46175.1 - 0.00083 19.5 2.7 1.2 9.4 0.8 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 OWF46175.1 - 0.00099 19.5 0.2 0.088 13.2 0.3 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain SR-25 PF10500.9 OWF46175.1 - 0.0037 16.9 7.5 0.0037 16.9 7.5 3.4 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein Arm PF00514.23 OWF46175.1 - 0.024 14.7 0.5 7.3 6.8 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Alpha_adaptinC2 PF02883.20 OWF46175.1 - 0.03 14.6 0.1 0.093 13.0 0.1 1.8 1 0 0 1 1 1 0 Adaptin C-terminal domain Vac14_Fab1_bd PF12755.7 OWF46175.1 - 0.16 12.6 1.2 1.2 9.8 0.0 3.1 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region NST1 PF13945.6 OWF46175.1 - 1.4 9.0 30.8 3 7.9 5.0 3.5 3 0 0 3 3 3 0 Salt tolerance down-regulator 4HBT PF03061.22 OWF46176.1 - 9.7e-15 54.7 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OWF46176.1 - 0.00096 19.3 0.1 0.0012 18.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 OWF46176.1 - 0.0012 19.1 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Dynamin_N PF00350.23 OWF46177.1 - 2.4e-21 76.5 1.2 1.1e-20 74.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Pkinase PF00069.25 OWF46177.1 - 2.8e-17 63.0 0.1 8.7e-17 61.3 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF46177.1 - 3.2e-16 59.4 0.1 7.6e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.23 OWF46177.1 - 7e-09 35.8 0.0 6.2e-06 26.3 0.0 3.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF46177.1 - 8.3e-05 22.6 0.7 0.00041 20.3 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 OWF46177.1 - 0.00099 18.5 0.6 0.015 14.6 0.0 2.9 3 0 0 3 3 3 1 AIG1 family Thioredox_DsbH PF03190.15 OWF46177.1 - 0.0013 18.7 0.3 1.4 8.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF255 Kinase-like PF14531.6 OWF46177.1 - 0.0017 17.7 0.9 0.007 15.7 0.1 2.2 2 0 0 2 2 2 1 Kinase-like NPR1_like_C PF12313.8 OWF46177.1 - 0.0042 16.6 2.3 0.17 11.4 2.7 2.5 2 0 0 2 2 2 1 NPR1/NIM1 like defence protein C terminal ABC_tran PF00005.27 OWF46177.1 - 0.0076 16.8 0.8 0.051 14.1 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OWF46177.1 - 0.0096 16.3 0.3 0.049 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain IIGP PF05049.13 OWF46177.1 - 0.011 14.8 0.0 0.011 14.8 0.0 2.5 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 OWF46177.1 - 0.023 14.0 1.8 0.077 12.3 0.0 2.6 2 1 0 2 2 2 0 Septin T2SSE PF00437.20 OWF46177.1 - 0.087 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 OWF46177.1 - 0.28 11.3 0.0 0.28 11.3 0.0 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain RRF PF01765.19 OWF46177.1 - 4.5 7.2 13.5 0.41 10.6 3.0 2.9 2 0 0 2 2 2 0 Ribosome recycling factor TFIIE_beta PF02186.15 OWF46178.1 - 7.7e-16 58.1 0.0 2.8e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 OWF46178.1 - 0.00059 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 zf-H2C2_5 PF13909.6 OWF46179.1 - 0.0019 17.9 0.7 0.0049 16.6 0.7 1.7 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 OWF46179.1 - 0.01 16.1 0.3 0.01 16.1 0.3 2.0 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_7 PF15269.6 OWF46179.1 - 0.048 13.7 0.4 0.092 12.8 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger zf-C2H2_4 PF13894.6 OWF46179.1 - 0.2 12.6 0.2 0.2 12.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OWF46179.1 - 0.32 11.1 1.6 2.4 8.2 1.6 1.9 1 1 0 1 1 1 0 Aberrant zinc-finger GAGA PF09237.11 OWF46179.1 - 0.87 9.4 4.4 3.9 7.3 0.8 2.5 2 0 0 2 2 2 0 GAGA factor Atg14 PF10186.9 OWF46180.1 - 0.022 13.8 4.8 1.2 8.2 0.7 2.6 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 WEMBL PF05701.11 OWF46180.1 - 0.22 10.2 0.1 0.42 9.3 0.1 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light OEP PF02321.18 OWF46180.1 - 0.54 10.0 3.6 2.9 7.7 1.2 2.4 1 1 2 3 3 3 0 Outer membrane efflux protein Chorein_N PF12624.7 OWF46180.1 - 6.7 6.9 9.9 19 5.4 0.5 2.9 1 1 2 3 3 3 0 N-terminal region of Chorein or VPS13 Mucin-like PF16058.5 OWF46181.1 - 8.8e-36 122.0 15.7 1.4e-09 38.0 0.0 5.6 1 1 4 6 6 6 6 Mucin-like NRD1_2 PF01995.16 OWF46181.1 - 0.0051 16.1 14.3 0.01 15.1 1.9 4.2 2 1 1 3 3 3 2 NrpR regulatory domains NRD1 and 2 Synuclein PF01387.17 OWF46181.1 - 0.66 10.2 22.9 21 5.3 1.7 6.0 1 1 6 8 8 8 0 Synuclein Prominin PF05478.11 OWF46181.1 - 0.89 7.4 1.7 1.4 6.7 1.7 1.2 1 0 0 1 1 1 0 Prominin Tektin PF03148.14 OWF46183.1 - 3.2e-142 473.8 35.7 3.6e-142 473.7 35.7 1.0 1 0 0 1 1 1 1 Tektin family DUF4600 PF15372.6 OWF46183.1 - 0.0051 17.2 6.1 0.0051 17.2 6.1 3.7 2 2 1 3 3 3 1 Domain of unknown function (DUF4600) DUF1664 PF07889.12 OWF46183.1 - 0.0091 16.0 19.2 0.27 11.3 0.6 4.3 4 0 0 4 4 4 2 Protein of unknown function (DUF1664) LIF_OSM PF01291.17 OWF46183.1 - 0.019 15.1 2.0 0.062 13.4 0.3 2.5 2 1 1 3 3 3 0 LIF / OSM family E2R135 PF11570.8 OWF46183.1 - 0.021 15.1 5.8 0.025 14.9 3.5 2.3 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF4618 PF15397.6 OWF46183.1 - 0.23 10.9 25.6 0.42 10.0 4.1 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.12 OWF46183.1 - 0.67 10.0 9.5 0.67 10.0 0.3 3.7 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus betaPIX_CC PF16523.5 OWF46183.1 - 1 9.2 8.1 0.3 10.9 0.3 3.5 2 1 1 3 3 3 0 betaPIX coiled coil XhlA PF10779.9 OWF46183.1 - 2.3 8.5 16.3 1.4 9.2 0.3 4.1 4 0 0 4 4 3 0 Haemolysin XhlA DUF5082 PF16888.5 OWF46183.1 - 4.2 7.7 29.1 0.11 12.8 1.3 4.6 4 2 1 5 5 5 0 Domain of unknown function (DUF5082) AAA_13 PF13166.6 OWF46183.1 - 5.3 5.6 28.4 0.11 11.1 10.4 3.0 1 1 1 3 3 3 0 AAA domain FliD_C PF07195.12 OWF46183.1 - 5.5 6.3 11.9 2.1 7.7 1.6 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF4795 PF16043.5 OWF46183.1 - 7.2 6.2 29.6 0.093 12.3 12.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) GAS PF13851.6 OWF46183.1 - 9.3 5.5 30.6 0.49 9.7 0.7 3.8 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OWF46184.1 - 5.7e-26 91.1 27.8 5.7e-26 91.1 27.8 12.8 4 2 9 13 13 13 4 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 OWF46184.1 - 0.00035 20.9 8.9 0.00035 20.9 8.9 11.8 2 2 9 11 11 11 2 Autophagy protein 16 (ATG16) Spectrin PF00435.21 OWF46185.1 - 0.0047 17.4 5.2 0.0047 17.4 5.2 6.3 2 1 5 7 7 7 1 Spectrin repeat Med9 PF07544.13 OWF46185.1 - 0.01 15.9 5.2 0.01 15.9 5.2 6.8 3 3 2 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 RBD-FIP PF09457.10 OWF46185.1 - 0.049 13.5 1.1 0.049 13.5 1.1 3.3 2 0 0 2 2 2 0 FIP domain DAG1 PF05454.11 OWF46185.1 - 4.6 6.5 6.2 0.49 9.7 0.7 2.1 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PMSR PF01625.21 OWF46185.1 - 8 6.6 7.4 0.81 9.9 1.6 2.4 2 0 0 2 2 2 0 Peptide methionine sulfoxide reductase MR_MLE_C PF13378.6 OWF46186.1 - 8.8e-57 192.2 0.1 1.2e-56 191.7 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OWF46186.1 - 3.6e-05 23.9 0.0 7.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 OWF46186.1 - 0.00042 19.5 0.0 0.00065 18.9 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Strumpellin PF10266.9 OWF46187.1 - 0 1638.3 24.9 0 1638.1 24.9 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin FAD_SOX PF18371.1 OWF46187.1 - 0.2 12.0 1.2 1.5 9.2 0.1 3.2 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Rhomboid PF01694.22 OWF46188.1 - 7.8e-24 84.4 11.1 7.8e-24 84.4 11.1 1.9 2 0 0 2 2 2 1 Rhomboid family DUF3357 PF11837.8 OWF46188.1 - 0.01 16.3 0.1 7.9 7.0 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3357) DUF5383 PF17355.2 OWF46188.1 - 0.27 11.6 3.6 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) FA_desaturase PF00487.24 OWF46188.1 - 5 6.9 12.5 3.4 7.4 9.9 2.1 1 1 0 1 1 1 0 Fatty acid desaturase preSET_CXC PF18264.1 OWF46189.1 - 0.06 13.8 19.7 0.16 12.5 19.7 1.7 1 0 0 1 1 1 0 CXC domain Sua5_yciO_yrdC PF01300.18 OWF46190.1 - 2.9e-28 98.6 0.0 4.4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Flp_Fap PF04964.14 OWF46190.1 - 0.29 11.0 1.8 0.65 9.9 0.1 2.6 2 0 0 2 2 2 0 Flp/Fap pilin component Sua5_yciO_yrdC PF01300.18 OWF46191.1 - 2.5e-31 108.5 0.0 3.7e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Gpr1_Fun34_YaaH PF01184.19 OWF46191.1 - 0.0037 16.9 17.7 0.0037 16.9 17.7 3.7 3 1 0 3 3 3 2 GPR1/FUN34/yaaH family Glyoxalase PF00903.25 OWF46192.1 - 1.6e-10 41.2 0.0 3.5e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OWF46192.1 - 9e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 OWF46192.1 - 0.0031 17.8 0.0 0.014 15.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OWF46192.1 - 0.042 14.0 0.0 0.086 13.0 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain HU-CCDC81_euk_1 PF14908.6 OWF46192.1 - 0.1 12.8 0.0 0.39 10.9 0.0 1.9 1 1 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 Skp1_POZ PF03931.15 OWF46193.1 - 4.3e-11 42.8 0.0 6.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain ECH_1 PF00378.20 OWF46194.1 - 2.9e-39 134.9 0.0 3.8e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF46194.1 - 7.3e-23 81.6 0.2 9.1e-23 81.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_C1 PF00112.23 OWF46195.1 - 5e-59 200.0 1.0 7.9e-59 199.4 1.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 OWF46195.1 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Somatomedin_B PF01033.17 OWF46195.1 - 0.0073 16.7 17.3 0.0073 16.7 17.3 2.9 3 1 1 4 4 4 1 Somatomedin B domain Peptidase_C1_2 PF03051.15 OWF46195.1 - 0.012 14.5 1.0 0.089 11.5 0.3 2.4 3 0 0 3 3 3 0 Peptidase C1-like family HECT PF00632.25 OWF46196.1 - 2e-45 155.6 0.0 3.1e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC10 PF03256.16 OWF46196.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 OWF46196.1 - 0.00073 19.6 0.0 0.0029 17.7 0.0 2.0 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 OWF46197.1 - 3e-08 33.8 0.3 4.6e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 F5/8 type C domain Laminin_EGF PF00053.24 OWF46197.1 - 0.0018 18.4 121.2 4.5 7.5 9.5 7.8 1 1 6 7 7 7 6 Laminin EGF domain DUF2014 PF09427.10 OWF46197.1 - 0.15 11.4 0.1 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Gal-3-0_sulfotr PF06990.11 OWF46198.1 - 1.1e-48 166.1 0.7 1.5e-48 165.7 0.7 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF46198.1 - 0.016 15.1 0.5 0.05 13.5 0.3 2.1 1 1 1 2 2 2 0 Sulfotransferase family COesterase PF00135.28 OWF46199.1 - 6.7e-125 417.9 0.0 7.8e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OWF46199.1 - 0.0054 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OWF46199.1 - 0.017 15.0 0.3 0.068 13.0 0.3 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1765 PF08578.10 OWF46200.1 - 1.7 9.1 13.5 6.5 7.2 1.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1765) LRR_8 PF13855.6 OWF46201.1 - 1.4e-05 24.7 2.1 3e-05 23.7 2.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OWF46201.1 - 0.0028 18.0 5.5 0.0065 16.9 5.5 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) DUF2976 PF11190.8 OWF46201.1 - 0.013 15.3 0.5 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) LRR_6 PF13516.6 OWF46201.1 - 0.38 10.9 3.3 0.85 9.8 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeat FGFR3_TM PF18123.1 OWF46201.1 - 1.3 8.6 6.9 6 6.5 0.5 2.2 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain Peptidase_C39 PF03412.15 OWF46202.1 - 0.022 14.6 0.3 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Peptidase C39 family LapA_dom PF06305.11 OWF46202.1 - 0.033 14.0 1.4 0.13 12.1 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain dCache_2 PF08269.11 OWF46202.1 - 0.054 12.7 3.0 1.2 8.2 0.4 2.7 2 0 0 2 2 2 0 Cache domain DUF2203 PF09969.9 OWF46202.1 - 0.064 14.0 5.7 1.6 9.5 0.7 3.5 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) NICE-3 PF07406.11 OWF46202.1 - 0.066 13.2 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 NICE-3 protein TPR_MLP1_2 PF07926.12 OWF46202.1 - 0.18 11.8 11.6 8.5 6.5 0.8 4.8 5 1 0 5 5 5 0 TPR/MLP1/MLP2-like protein Suppressor_APC PF11414.8 OWF46202.1 - 0.28 11.3 4.1 6.4 6.9 0.5 3.1 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein BLOC1_2 PF10046.9 OWF46202.1 - 0.79 10.1 16.4 0.24 11.7 1.0 4.6 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 OWF46202.1 - 1.1 9.5 19.4 2.8 8.3 0.5 4.9 2 2 4 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OWF46202.1 - 1.5 8.9 27.4 0.16 12.0 2.6 5.3 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) BMFP PF04380.13 OWF46202.1 - 1.9 9.0 4.9 18 5.9 1.5 4.1 3 1 0 3 3 3 0 Membrane fusogenic activity Peptidase_M9_N PF08453.10 OWF46202.1 - 2.3 7.9 5.3 0.73 9.5 0.4 2.6 2 1 1 3 3 3 0 Peptidase family M9 N-terminal DUF4164 PF13747.6 OWF46202.1 - 3.8 7.9 7.1 5.5 7.3 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) Sec34 PF04136.15 OWF46202.1 - 4.4 7.2 18.9 0.42 10.5 0.6 4.8 2 2 4 6 6 6 0 Sec34-like family Matrilin_ccoil PF10393.9 OWF46202.1 - 7.2 6.6 7.4 66 3.5 0.1 4.4 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin RCR PF12273.8 OWF46203.1 - 0.023 15.4 2.0 3.2 8.4 0.3 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF4083 PF13314.6 OWF46203.1 - 0.073 13.0 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) TMEM154 PF15102.6 OWF46203.1 - 0.21 11.5 1.9 1.4 8.8 0.0 2.6 2 1 0 2 2 2 0 TMEM154 protein family Glycophorin_A PF01102.18 OWF46203.1 - 0.56 10.4 0.0 0.56 10.4 0.0 2.5 4 0 0 4 4 4 0 Glycophorin A Insulin_TMD PF17870.1 OWF46204.1 - 0.045 13.8 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TMEM154 PF15102.6 OWF46204.1 - 0.063 13.2 1.9 0.4 10.6 0.0 2.6 2 0 0 2 2 2 0 TMEM154 protein family Shisa PF13908.6 OWF46204.1 - 0.87 9.8 0.0 0.87 9.8 0.0 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator RNF220 PF15926.5 OWF46205.1 - 2.9e-85 285.9 0.7 6.5e-85 284.7 0.7 1.7 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 OWF46205.1 - 5.4e-12 45.3 11.0 5.4e-12 45.3 11.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF46205.1 - 0.00033 20.4 8.1 0.00033 20.4 8.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF46205.1 - 0.00042 20.2 8.5 0.00042 20.2 8.5 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF46205.1 - 0.00078 19.3 10.3 0.00078 19.3 10.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF46205.1 - 0.0068 16.7 10.4 0.0068 16.7 10.4 3.3 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 OWF46205.1 - 0.062 13.2 19.4 0.19 11.6 6.4 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 OWF46205.1 - 0.27 11.5 0.1 0.27 11.5 0.1 3.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Endonuclease_7 PF02945.15 OWF46205.1 - 0.39 10.7 13.7 0.088 12.7 1.5 3.2 3 0 0 3 3 3 0 Recombination endonuclease VII zf-RING_UBOX PF13445.6 OWF46205.1 - 0.62 10.1 20.2 0.028 14.4 6.2 3.3 3 0 0 3 3 3 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF46205.1 - 0.69 10.0 6.8 0.63 10.1 3.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_9 PF16293.5 OWF46205.1 - 1.1 9.1 6.9 3.6 7.5 0.1 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-ribbon_3 PF13248.6 OWF46205.1 - 4.8 6.7 11.3 42 3.7 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_10 PF16685.5 OWF46205.1 - 9.1 6.5 12.1 0.88 9.8 6.0 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Aminotran_1_2 PF00155.21 OWF46206.1 - 1.1e-37 130.1 0.0 1.2e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF902 PF06001.13 OWF46206.1 - 0.4 11.2 3.1 1.1 9.9 3.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) Sel1 PF08238.12 OWF46208.1 - 1.4e-05 25.6 4.8 0.028 15.1 0.1 4.5 5 0 0 5 5 5 2 Sel1 repeat DUF5630 PF18632.1 OWF46208.1 - 0.00085 18.7 1.7 0.0013 18.1 1.7 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5630) TPR_1 PF00515.28 OWF46208.1 - 0.0089 15.8 0.5 0.24 11.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3089 PF11288.8 OWF46208.1 - 0.056 13.0 0.1 0.44 10.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3089) ADK PF00406.22 OWF46209.1 - 1.6e-33 115.9 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OWF46209.1 - 4.9e-30 104.7 0.0 6e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF46209.1 - 0.0022 18.2 0.0 0.0026 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OWF46209.1 - 0.0032 18.0 0.2 0.011 16.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 OWF46209.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OWF46209.1 - 0.039 13.2 0.1 0.046 13.0 0.1 1.4 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 OWF46209.1 - 0.062 13.6 0.1 0.077 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain STIL_N PF15253.6 OWF46210.1 - 5.9e-109 364.7 0.0 1.4e-108 363.5 0.0 1.6 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus Med26 PF08711.11 OWF46211.1 - 1.4e-13 50.6 3.2 1.4e-13 50.6 1.4 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Med26_C PF15693.5 OWF46211.1 - 9.6e-12 45.4 0.5 9.6e-12 45.4 0.5 3.0 3 0 0 3 3 3 1 Mediator complex subunit 26 C-terminal LTV PF04180.14 OWF46212.1 - 3.2e-79 267.4 31.8 1.8e-76 258.4 31.8 2.6 1 1 0 1 1 1 1 Low temperature viability protein CABIT PF12736.7 OWF46213.1 - 5.8e-14 52.1 0.7 1.1e-05 24.9 0.0 4.3 2 2 1 3 3 3 3 Cell-cycle sustaining, positive selection, CREPT PF16566.5 OWF46214.1 - 1.5e-05 25.2 2.6 19 5.4 0.1 5.7 1 1 3 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour CX9C PF16860.5 OWF46214.1 - 3.6e-05 23.7 48.5 3 7.9 0.5 9.8 4 3 5 10 10 10 4 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Paramyx_P_V_C PF03210.13 OWF46214.1 - 7.7e-05 22.5 0.5 12 5.7 0.0 5.2 1 1 2 5 5 5 1 Paramyxovirus P/V phosphoprotein C-terminal DUF948 PF06103.11 OWF46214.1 - 0.0029 17.8 0.1 1.6 9.0 0.1 4.2 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DCX PF03607.17 OWF46214.1 - 0.0052 16.9 12.1 1.5e+02 2.6 0.1 9.2 1 1 6 7 7 7 0 Doublecortin SesA PF17107.5 OWF46214.1 - 0.03 14.5 0.0 16 5.7 0.0 3.9 2 2 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Coatomer_WDAD PF04053.14 OWF46214.1 - 0.065 12.3 3.3 48 2.8 0.0 5.0 1 1 6 7 7 7 0 Coatomer WD associated region DHR10 PF18595.1 OWF46214.1 - 0.12 12.5 6.6 46 4.1 0.1 6.2 1 1 7 9 9 9 0 Designed helical repeat protein 10 domain Thioredoxin_9 PF14595.6 OWF46214.1 - 0.52 10.1 13.7 1.1e+02 2.5 0.1 7.3 4 3 4 10 10 10 0 Thioredoxin DUF3128 PF11326.8 OWF46214.1 - 0.84 10.1 15.7 31 5.0 0.3 5.6 2 2 4 6 6 6 0 Protein of unknown function (DUF3128) FANCI_S4 PF14678.6 OWF46214.1 - 1 8.5 5.1 4.4 6.4 0.3 2.8 1 1 2 3 3 3 0 FANCI solenoid 4 VPS28 PF03997.12 OWF46214.1 - 2.2 7.9 4.7 22 4.7 0.5 3.1 1 1 2 4 4 4 0 VPS28 protein SLR1-BP PF07333.12 OWF46214.1 - 2.9 8.4 23.3 9.3 6.8 2.3 5.6 1 1 3 4 4 4 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) DUF4983 PF16356.5 OWF46214.1 - 8.3 7.3 16.4 5.9 7.8 0.2 5.6 1 1 5 6 6 6 0 Domain of unknown function (DUF4983) CX9C PF16860.5 OWF46215.1 - 4.6e-05 23.3 52.9 1.3 9.1 1.7 10.7 2 2 8 13 13 13 4 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CREPT PF16566.5 OWF46215.1 - 6e-05 23.3 0.6 13 6.0 0.0 5.4 1 1 5 6 6 6 1 Cell-cycle alteration and expression-elevated protein in tumour MKT1_C PF12246.8 OWF46215.1 - 0.0034 16.7 0.0 37 3.4 0.0 4.4 1 1 3 4 4 4 0 Temperature dependent protein affecting M2 dsRNA replication DUF3151 PF11349.8 OWF46215.1 - 0.0077 16.3 0.0 61 3.7 0.0 4.8 1 1 4 7 7 7 0 Protein of unknown function (DUF3151) SesA PF17107.5 OWF46215.1 - 0.024 14.8 0.0 16 5.7 0.0 4.4 4 1 2 6 6 6 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ArsA_HSP20 PF17886.1 OWF46215.1 - 0.041 13.5 0.3 12 5.6 0.0 2.3 2 0 0 2 2 2 0 HSP20-like domain found in ArsA DCX PF03607.17 OWF46215.1 - 0.061 13.4 15.2 25 5.1 0.1 9.0 4 4 3 7 7 7 0 Doublecortin Coatomer_WDAD PF04053.14 OWF46215.1 - 0.68 8.9 4.9 1.1e+02 1.7 0.1 5.2 3 3 5 9 9 9 0 Coatomer WD associated region TTc_toxin_rep PF18807.1 OWF46216.1 - 0.069 13.0 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 0 Tripartite Tc toxins repeat RcsD_ABL PF16359.5 OWF46217.1 - 1.9e-08 34.4 0.4 3.7 7.7 0.0 4.9 1 1 7 8 8 8 7 RcsD-ABL domain RcsC PF09456.10 OWF46217.1 - 2.4e-07 30.6 0.1 9 6.4 0.0 4.9 1 1 5 6 6 6 3 RcsC Alpha-Beta-Loop (ABL) Cadherin_3 PF16184.5 OWF46217.1 - 0.00022 21.2 0.0 43 4.2 0.0 4.6 1 1 5 6 6 6 0 Cadherin-like Kisspeptin PF15152.6 OWF46217.1 - 0.021 15.6 1.1 53 4.7 0.0 4.3 1 1 4 5 5 5 0 Kisspeptin FTHFS PF01268.19 OWF46217.1 - 0.03 12.5 11.0 0.57 8.3 0.4 3.7 1 1 4 5 5 5 0 Formate--tetrahydrofolate ligase Smac_DIABLO PF09057.10 OWF46217.1 - 0.19 11.1 1.0 18 4.6 0.1 3.9 1 1 4 5 5 5 0 Second Mitochondria-derived Activator of Caspases MOSC_N PF03476.16 OWF46217.1 - 0.74 9.7 3.9 38 4.2 0.9 3.6 1 1 2 3 3 3 0 MOSC N-terminal beta barrel domain SAM_2 PF07647.17 OWF46218.1 - 1.4e-21 76.3 1.4 6.7e-12 45.3 0.0 3.3 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF46218.1 - 5.7e-18 65.1 1.0 4.6e-13 49.4 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 OWF46218.1 - 2.1e-10 41.3 0.1 6.7e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 TIR domain SAM_3 PF18016.1 OWF46218.1 - 0.00043 20.0 0.1 0.042 13.6 0.0 2.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF46218.1 - 0.033 14.1 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3432 PF11914.8 OWF46219.1 - 4.9e-05 23.5 5.8 6.8e-05 23.0 2.6 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) BES1_N PF05687.13 OWF46219.1 - 0.14 12.6 0.8 0.17 12.3 0.8 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF2457 PF10446.9 OWF46219.1 - 0.33 10.1 5.3 0.36 9.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) 7tm_3 PF00003.22 OWF46220.1 - 4.3e-33 115.0 16.3 7.4e-33 114.2 16.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OWF46220.1 - 3.1e-28 98.9 0.1 4.3e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF46220.1 - 0.00021 21.1 0.5 0.00034 20.4 0.5 1.3 1 0 0 1 1 1 1 Periplasmic binding protein His_Phos_1 PF00300.22 OWF46221.1 - 6.9e-17 61.8 0.0 1.9e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.6 OWF46221.1 - 1e-12 47.7 0.2 4.2e-12 45.7 0.2 2.2 1 0 0 1 1 1 1 Variant SH3 domain LigT_PEase PF02834.16 OWF46221.1 - 4.8e-06 26.7 0.0 0.059 13.6 0.0 2.4 2 0 0 2 2 2 2 LigT like Phosphoesterase SH3_1 PF00018.28 OWF46221.1 - 8.1e-05 22.2 0.2 0.00018 21.1 0.2 1.6 1 0 0 1 1 1 1 SH3 domain 2_5_RNA_ligase2 PF13563.6 OWF46221.1 - 0.00072 19.5 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily SH3_2 PF07653.17 OWF46221.1 - 0.0018 17.9 0.1 0.0042 16.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain UBA PF00627.31 OWF46221.1 - 0.002 18.0 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Pox_A21 PF05323.12 OWF46221.1 - 4.9 7.8 5.1 1.3 9.6 0.9 2.2 2 1 0 2 2 2 0 Poxvirus A21 Protein DUF1043 PF06295.12 OWF46222.1 - 0.0094 15.9 0.4 0.016 15.2 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) TPR_MLP1_2 PF07926.12 OWF46222.1 - 0.013 15.6 0.6 1.9 8.5 0.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 OWF46222.1 - 0.032 14.4 0.8 0.062 13.5 0.6 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour KxDL PF10241.9 OWF46222.1 - 0.057 13.7 3.7 0.13 12.6 3.1 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF5344 PF17279.2 OWF46222.1 - 0.065 13.8 0.6 0.13 12.9 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5344) TMF_DNA_bd PF12329.8 OWF46222.1 - 0.086 12.9 2.5 0.16 12.0 0.8 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4757 PF15949.5 OWF46222.1 - 0.089 13.3 9.8 0.079 13.4 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Jnk-SapK_ap_N PF09744.9 OWF46222.1 - 0.28 11.4 5.4 2.5 8.3 4.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 PH PF00169.29 OWF46223.1 - 1.2e-18 67.5 0.0 2.4e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 PH domain Metallophos PF00149.28 OWF46223.1 - 3e-11 44.2 5.6 1.2e-10 42.2 4.2 2.4 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase PH_8 PF15409.6 OWF46223.1 - 0.00057 20.1 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 OWF46223.1 - 0.0053 16.6 0.1 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Phospholip_B PF04916.13 OWF46224.1 - 4.4e-189 629.5 0.2 5.4e-189 629.2 0.2 1.0 1 0 0 1 1 1 1 Phospholipase B TBCC PF07986.12 OWF46225.1 - 5.9e-32 109.9 0.1 1.1e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OWF46225.1 - 0.0033 17.0 0.2 0.0052 16.4 0.2 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PID PF00640.23 OWF46226.1 - 3.8e-42 143.6 0.1 8.3e-42 142.5 0.1 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 OWF46226.1 - 2.7e-25 88.5 2.9 1.4e-11 44.6 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OWF46226.1 - 1.9e-16 59.6 0.8 6.8e-07 29.0 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OWF46226.1 - 0.00072 19.8 0.1 0.0082 16.4 0.0 2.4 2 0 0 2 2 2 1 PDZ domain NRho PF16733.5 OWF46226.1 - 0.022 14.8 0.1 0.06 13.4 0.1 1.7 1 0 0 1 1 1 0 Rhomboid N-terminal domain GTP_EFTU PF00009.27 OWF46227.1 - 4.6e-64 215.6 0.2 6.6e-64 215.0 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OWF46227.1 - 9.6e-31 106.1 0.1 4.6e-30 103.9 0.0 2.2 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.24 OWF46227.1 - 2.6e-21 75.5 0.0 8.4e-21 73.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OWF46227.1 - 8e-13 48.3 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OWF46227.1 - 5.8e-12 45.8 0.0 2.1e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF46227.1 - 0.00022 21.3 0.0 0.00068 19.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Staygreen PF12638.7 OWF46227.1 - 0.029 14.2 0.1 0.066 13.0 0.1 1.6 1 0 0 1 1 1 0 Staygreen protein Pkinase PF00069.25 OWF46228.1 - 7.8e-54 182.8 1.3 1.7e-52 178.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF46228.1 - 1.5e-30 106.4 0.0 1.5e-30 106.4 0.0 2.0 2 0 0 2 2 1 1 Protein tyrosine kinase PB1 PF00564.24 OWF46228.1 - 3.8e-09 36.4 0.0 7.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 OWF46228.1 - 1.7e-08 33.7 0.1 2.7e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase TFIIA PF03153.13 OWF46228.1 - 2.2e-05 24.6 31.0 2.8e-05 24.3 31.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 OWF46228.1 - 0.00029 21.1 3.5 0.00044 20.5 3.5 1.3 1 0 0 1 1 1 1 DDHD domain EPL1 PF10513.9 OWF46228.1 - 0.00054 20.4 8.9 0.001 19.5 8.9 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like Velvet PF11754.8 OWF46228.1 - 0.0084 16.1 8.8 0.0084 16.1 8.8 1.5 2 0 0 2 2 1 1 Velvet factor NARP1 PF12569.8 OWF46228.1 - 0.011 14.7 4.9 0.014 14.3 4.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UPF0560 PF10577.9 OWF46228.1 - 0.022 13.3 14.2 0.031 12.8 14.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.9 OWF46228.1 - 0.024 12.9 26.8 0.033 12.5 26.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 OWF46228.1 - 0.038 12.8 14.1 0.053 12.3 14.1 1.1 1 0 0 1 1 1 0 Presenilin Rrn6 PF10214.9 OWF46228.1 - 0.038 12.5 13.4 0.051 12.1 13.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CPSF100_C PF13299.6 OWF46228.1 - 0.046 13.9 9.6 0.073 13.3 9.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 OWF46228.1 - 0.063 13.1 10.1 0.11 12.3 10.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus Haspin_kinase PF12330.8 OWF46228.1 - 0.095 11.6 0.0 0.095 11.6 0.0 2.3 2 1 0 2 2 1 0 Haspin like kinase domain ABC2_membrane_2 PF12679.7 OWF46228.1 - 0.097 11.9 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SpoIIP PF07454.11 OWF46228.1 - 0.1 12.1 13.4 0.15 11.5 13.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_23 PF13476.6 OWF46228.1 - 0.12 12.9 13.5 0.18 12.3 13.5 1.3 1 0 0 1 1 1 0 AAA domain DUF4746 PF15928.5 OWF46228.1 - 0.15 11.5 7.7 0.22 10.9 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PIP5K PF01504.18 OWF46228.1 - 0.17 11.0 7.7 0.26 10.5 7.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Spt20 PF12090.8 OWF46228.1 - 0.18 11.4 46.1 0.36 10.4 46.1 1.5 1 0 0 1 1 1 0 Spt20 family Endostatin PF06482.11 OWF46228.1 - 0.2 11.1 13.3 0.33 10.4 13.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4407 PF14362.6 OWF46228.1 - 0.23 10.7 15.8 0.33 10.3 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pex14_N PF04695.13 OWF46228.1 - 0.24 12.1 29.2 0.42 11.3 29.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MCU PF04678.13 OWF46228.1 - 0.4 10.8 6.7 0.63 10.1 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter MRP-S27 PF10037.9 OWF46228.1 - 0.49 9.2 13.9 0.61 8.9 13.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Ndc1_Nup PF09531.10 OWF46228.1 - 0.52 8.9 11.2 0.76 8.4 11.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cu-oxidase_4 PF02578.15 OWF46228.1 - 0.56 9.8 5.1 1.1 8.8 5.1 1.4 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase EIF4E-T PF10477.9 OWF46228.1 - 0.67 8.7 20.5 0.88 8.3 20.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E EOS1 PF12326.8 OWF46228.1 - 0.77 9.7 4.3 1.3 9.0 4.3 1.3 1 0 0 1 1 1 0 N-glycosylation protein Band_3_cyto PF07565.13 OWF46228.1 - 0.77 9.5 13.3 1.2 8.9 13.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF913 PF06025.12 OWF46228.1 - 0.79 8.6 7.7 1.2 8.0 7.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TERB2 PF15101.6 OWF46228.1 - 1.2 9.1 19.8 2 8.4 19.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Serinc PF03348.15 OWF46228.1 - 1.3 7.9 5.3 1.7 7.5 5.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) MMR1 PF08505.10 OWF46228.1 - 1.4 9.1 18.2 2.1 8.6 18.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.16 OWF46228.1 - 1.5 8.9 10.5 2.2 8.2 10.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4820 PF16091.5 OWF46228.1 - 1.5 8.1 12.4 2.5 7.4 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Hid1 PF12722.7 OWF46228.1 - 1.6 6.8 12.2 2.2 6.3 12.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 OWF46228.1 - 2 7.1 13.7 3 6.5 13.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PepSY_TM PF03929.16 OWF46228.1 - 2.5 7.7 5.4 3.8 7.1 5.4 1.2 1 0 0 1 1 1 0 PepSY-associated TM region SLC12 PF03522.15 OWF46228.1 - 2.9 6.8 15.4 4.6 6.1 15.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 LMBR1 PF04791.16 OWF46228.1 - 4.9 5.9 8.2 12 4.7 7.6 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein Zip PF02535.22 OWF46228.1 - 6.7 5.8 7.8 11 5.2 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4175 PF13779.6 OWF46228.1 - 9.5 4.0 35.2 13 3.6 35.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Keratin_assoc PF09775.9 OWF46229.1 - 2.6e-51 172.6 5.5 2.8e-51 172.5 5.5 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 Yip1 PF04893.17 OWF46229.1 - 0.0052 16.5 9.5 0.0068 16.1 9.5 1.2 1 0 0 1 1 1 1 Yip1 domain Phage_holin_8 PF16931.5 OWF46229.1 - 0.18 11.8 5.3 0.069 13.1 1.1 2.1 1 1 2 3 3 3 0 Putative phage holin TMEM247 PF15444.6 OWF46229.1 - 0.27 11.3 1.5 0.37 10.8 1.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 Bac_export_2 PF01312.19 OWF46229.1 - 0.35 10.0 2.3 0.39 9.9 2.3 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family PRA1 PF03208.19 OWF46229.1 - 0.44 10.2 7.5 3.1 7.4 1.1 2.1 2 0 0 2 2 2 0 PRA1 family protein Phage_holin_3_6 PF07332.11 OWF46229.1 - 0.88 9.6 5.6 0.69 10.0 4.2 1.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III COX14 PF14880.6 OWF46229.1 - 1.2 9.0 3.3 1 9.3 0.6 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF2970 PF11174.8 OWF46229.1 - 6 6.8 7.7 1.5 8.7 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2970) SCAPER_N PF16501.5 OWF46230.1 - 3.2e-42 142.5 0.0 1.2e-41 140.7 0.0 2.0 1 0 0 1 1 1 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 OWF46230.1 - 3e-07 30.6 0.3 7.9e-07 29.3 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF46230.1 - 0.014 15.6 0.2 0.054 13.8 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2929 PF11151.8 OWF46231.1 - 0.034 14.4 12.2 2.8 8.3 1.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2929) LIM PF00412.22 OWF46232.1 - 6.1e-29 100.0 17.4 1.4e-14 54.0 3.0 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 OWF46232.1 - 7.8e-16 57.7 0.9 1.5e-15 56.8 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF46232.1 - 4.4e-05 23.3 0.1 0.00011 22.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain RFXA_RFXANK_bdg PF15289.6 OWF46232.1 - 0.4 11.0 6.2 0.059 13.7 1.7 1.9 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain YhfH PF14149.6 OWF46232.1 - 3.9 7.5 10.4 4.1 7.5 0.4 3.6 4 0 0 4 4 4 0 YhfH-like protein Med27 PF11571.8 OWF46232.1 - 7.5 7.0 8.9 0.77 10.2 1.0 3.1 2 0 0 2 2 2 0 Mediator complex subunit 27 RVT_1 PF00078.27 OWF46235.1 - 8.4e-43 146.4 0.7 8.4e-43 146.4 0.7 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OWF46235.1 - 5e-05 23.1 0.0 0.0065 16.3 0.0 3.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4747 PF15931.5 OWF46236.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4747) NESP55 PF06390.12 OWF46236.1 - 3.1 7.3 11.8 5 6.6 11.8 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF3060 PF11259.8 OWF46238.1 - 0.35 10.6 31.5 0.15 11.8 6.9 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF3060) DUF3060 PF11259.8 OWF46239.1 - 1.2e-06 28.1 58.1 0.042 13.5 7.4 6.9 1 1 7 8 8 8 8 Protein of unknown function (DUF3060) DUF3060 PF11259.8 OWF46241.1 - 5.5e-11 42.0 99.6 0.011 15.4 5.7 8.9 3 1 7 10 10 10 8 Protein of unknown function (DUF3060) PID_2 PF14719.6 OWF46241.1 - 1.6 8.5 6.5 3.5 7.5 0.2 3.4 4 0 0 4 4 4 0 Phosphotyrosine interaction domain (PTB/PID) DUF3060 PF11259.8 OWF46242.1 - 3.1e-05 23.6 74.5 0.00058 19.5 6.3 8.9 1 1 8 9 9 9 9 Protein of unknown function (DUF3060) NPV_P10 PF05531.12 OWF46244.1 - 0.0045 17.4 4.0 0.049 14.1 0.2 3.6 1 1 3 4 4 4 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 OWF46244.1 - 0.0048 16.9 4.4 0.022 14.8 1.2 2.4 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus AIP3 PF03915.13 OWF46244.1 - 0.012 14.7 16.1 0.062 12.4 10.8 2.2 1 1 1 2 2 2 0 Actin interacting protein 3 CmlA_N PF18456.1 OWF46244.1 - 0.013 14.8 0.5 0.024 14.0 0.5 1.4 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Tox-GHH PF15636.6 OWF46244.1 - 0.029 14.4 0.1 0.078 13.0 0.1 1.8 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin ApoO PF09769.9 OWF46244.1 - 0.063 13.2 1.7 0.45 10.5 0.3 2.5 2 1 0 2 2 2 0 Apolipoprotein O LPP PF04728.13 OWF46244.1 - 0.095 13.1 4.6 36 4.8 0.6 5.3 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Apolipoprotein PF01442.18 OWF46244.1 - 0.098 12.5 7.8 0.066 13.1 4.5 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ABC_tran_CTD PF16326.5 OWF46244.1 - 0.1 12.9 4.2 14 6.0 0.0 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain DivIC PF04977.15 OWF46244.1 - 0.12 12.1 6.6 22 4.9 0.6 4.0 3 1 1 4 4 4 0 Septum formation initiator Lectin_N PF03954.14 OWF46244.1 - 0.14 11.9 11.5 0.15 11.8 3.4 3.3 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain PRKG1_interact PF15898.5 OWF46244.1 - 0.17 12.8 10.8 0.36 11.7 4.1 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Spectrin PF00435.21 OWF46244.1 - 0.21 12.1 3.9 0.25 11.9 0.7 2.6 1 1 0 2 2 2 0 Spectrin repeat CENP-F_leu_zip PF10473.9 OWF46244.1 - 0.24 11.4 13.4 5.4 7.0 7.8 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 OWF46244.1 - 0.25 10.8 18.8 1.9 7.9 5.4 2.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 Tup_N PF08581.10 OWF46244.1 - 0.26 11.6 5.0 2.5 8.4 0.3 3.2 3 1 0 3 3 3 0 Tup N-terminal ING PF12998.7 OWF46244.1 - 0.27 11.9 4.6 0.31 11.6 2.9 2.1 2 1 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF2937 PF11157.8 OWF46244.1 - 0.28 10.9 3.4 0.31 10.8 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Spc7 PF08317.11 OWF46244.1 - 0.6 8.9 13.8 0.3 9.9 6.3 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 OWF46244.1 - 0.7 10.2 7.9 1.1 9.6 0.3 3.5 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.9 OWF46244.1 - 0.71 10.0 12.7 11 6.2 0.4 2.9 1 1 2 3 3 3 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 OWF46244.1 - 0.87 10.0 8.1 0.55 10.7 0.5 3.9 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 OWF46244.1 - 1 7.8 3.2 1.3 7.4 3.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 OWF46244.1 - 1.1 9.3 12.1 0.9 9.6 1.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4239 PF14023.6 OWF46244.1 - 1.3 8.7 6.3 1.2 8.8 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF4200 PF13863.6 OWF46244.1 - 1.7 9.1 10.5 4.2 7.8 2.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 OWF46244.1 - 2.3 8.8 9.4 0.58 10.7 1.0 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lebercilin PF15619.6 OWF46244.1 - 3 7.4 13.0 5.2 6.7 11.0 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Remorin_C PF03763.13 OWF46244.1 - 3.4 7.6 6.9 20 5.1 3.8 2.9 2 2 0 2 2 2 0 Remorin, C-terminal region DUF2203 PF09969.9 OWF46244.1 - 5.4 7.8 7.2 3.4 8.4 2.3 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 OWF46244.1 - 8.9 5.8 14.1 1.3e+02 2.0 14.1 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Lectin_C PF00059.21 OWF46245.1 - 1.3e-09 38.8 0.1 3.2e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 OWF46245.1 - 0.0025 17.7 0.1 0.008 16.1 0.1 1.9 1 0 0 1 1 1 1 PAN domain Cyclin_N PF00134.23 OWF46246.1 - 6.3e-28 97.1 0.1 9.1e-28 96.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF46246.1 - 1.3e-06 28.5 0.1 4.5e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain TSP_C PF05735.12 OWF46247.1 - 6.7e-97 323.2 0.1 1.1e-96 322.5 0.1 1.4 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 OWF46247.1 - 4.3e-50 167.1 153.9 2e-13 49.8 13.7 9.6 7 2 1 8 8 8 8 Thrombospondin type 3 repeat EGF PF00008.27 OWF46247.1 - 1.4e-07 31.6 174.7 0.022 15.1 5.7 13.3 12 0 0 12 12 12 8 EGF-like domain EGF_CA PF07645.15 OWF46247.1 - 3e-07 30.5 20.6 9.6e-06 25.7 8.5 12.7 12 0 0 12 12 12 6 Calcium-binding EGF domain EGF_3 PF12947.7 OWF46247.1 - 5.5e-06 26.5 130.1 8.8e-06 25.8 3.7 13.3 12 0 0 12 12 12 5 EGF domain COMP PF11598.8 OWF46247.1 - 0.00028 21.3 5.5 0.00057 20.3 5.5 1.5 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein cEGF PF12662.7 OWF46247.1 - 0.00031 20.6 0.7 0.00031 20.6 0.7 15.1 14 5 0 14 14 14 3 Complement Clr-like EGF-like SK_channel PF03530.14 OWF46248.1 - 6.7e-44 148.6 2.1 6.7e-44 148.6 2.1 2.4 3 0 0 3 3 3 1 Calcium-activated SK potassium channel CaMBD PF02888.16 OWF46248.1 - 9.6e-35 118.6 5.9 9.6e-35 118.6 5.9 2.6 2 0 0 2 2 2 1 Calmodulin binding domain Ion_trans_2 PF07885.16 OWF46248.1 - 3.9e-15 55.6 0.6 1e-14 54.2 0.6 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 OWF46248.1 - 0.0053 16.0 11.1 0.014 14.6 9.9 2.2 1 1 0 1 1 1 1 Ion transport protein Macoilin PF09726.9 OWF46248.1 - 0.03 12.9 23.5 0.054 12.0 23.5 1.4 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 OWF46248.1 - 0.38 9.7 12.8 0.8 8.7 12.8 1.6 1 0 0 1 1 1 0 Solute carrier family 12 Vac7 PF12751.7 OWF46248.1 - 0.8 9.1 19.5 1.8 7.9 19.5 1.6 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DAG_kinase_N PF14513.6 OWF46248.1 - 1.5 9.0 12.2 11 6.2 10.2 2.8 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus TFIIA PF03153.13 OWF46248.1 - 2.8 7.8 34.3 0.072 13.1 26.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PMP1_2 PF08114.11 OWF46248.1 - 9.6 6.0 6.1 6.7 6.5 1.8 2.5 2 0 0 2 2 2 0 ATPase proteolipid family WD40_3 PF15911.5 OWF46250.1 - 6.2e-27 93.4 0.1 7.3e-26 89.9 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Clathrin PF00637.20 OWF46250.1 - 1.1e-12 48.1 2.0 0.00068 19.5 0.7 4.5 1 1 3 4 4 4 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 OWF46250.1 - 2.7e-12 46.8 1.0 0.0078 16.5 0.2 6.7 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OWF46250.1 - 3.8e-06 26.2 1.9 1.7 7.6 0.0 4.6 5 0 0 5 5 5 3 Coatomer WD associated region WD40 PF00400.32 OWF46250.1 - 4.8e-05 24.0 8.2 1.7 9.7 0.1 6.4 6 0 0 6 6 6 1 WD domain, G-beta repeat DZR PF12773.7 OWF46250.1 - 0.00027 20.9 6.1 0.0027 17.7 6.1 2.5 1 1 0 1 1 1 1 Double zinc ribbon ANAPC3 PF12895.7 OWF46250.1 - 0.00095 19.3 5.9 2.8 8.2 0.2 5.1 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OWF46250.1 - 0.0015 19.0 0.5 7.9 7.1 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 OWF46250.1 - 0.0069 15.8 10.8 0.015 14.7 2.1 3.0 3 0 0 3 3 3 2 zinc-ribbon domain TPR_7 PF13176.6 OWF46250.1 - 0.026 14.5 12.9 8.4 6.7 0.4 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46250.1 - 0.078 13.2 14.3 1.3 9.5 0.7 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 OWF46250.1 - 0.11 11.9 5.9 0.41 10.0 4.0 2.5 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP Alkyl_sulf_dimr PF14863.6 OWF46250.1 - 0.44 11.0 2.1 31 5.0 0.5 2.5 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_1 PF00515.28 OWF46250.1 - 1.2 9.1 12.7 42 4.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46250.1 - 1.5 9.9 16.9 0.97 10.4 1.0 6.2 6 1 1 7 7 6 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 OWF46250.1 - 1.5 8.6 12.8 0.05 13.3 3.5 2.9 3 0 0 3 3 2 0 zinc-ribbon domain TPR_2 PF07719.17 OWF46250.1 - 2 8.7 21.0 1.1 9.5 2.1 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat SNF PF00209.18 OWF46251.1 - 8.5e-198 658.3 36.5 4.8e-135 451.2 20.5 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family EpsG PF14897.6 OWF46252.1 - 0.22 10.8 12.8 0.27 10.5 6.4 2.3 2 0 0 2 2 2 0 EpsG family GPI2 PF06432.11 OWF46252.1 - 1.5 8.2 5.9 0.99 8.8 1.4 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Tetraspanin PF00335.20 OWF46252.1 - 1.8 8.2 8.6 16 5.1 0.1 3.1 3 0 0 3 3 3 0 Tetraspanin family Gal-3-0_sulfotr PF06990.11 OWF46253.1 - 2e-53 181.8 2.4 2.7e-53 181.3 2.4 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF46253.1 - 0.00029 20.8 0.9 0.0023 17.9 0.9 2.5 1 1 0 1 1 1 1 Sulfotransferase family Baculo_LEF5 PF04838.12 OWF46253.1 - 0.015 15.4 0.1 5.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 PsbY PF06298.11 OWF46256.1 - 1.7e-14 53.4 3.8 1.4e+02 2.4 0.0 18.8 18 6 5 23 23 23 0 Photosystem II protein Y (PsbY) Pentapeptide_2 PF01469.18 OWF46256.1 - 4.7e-05 23.2 33.2 0.14 12.0 4.5 9.3 6 3 0 6 6 6 2 Pentapeptide repeats (8 copies) DUF4605 PF15378.6 OWF46256.1 - 0.008 16.0 7.8 17 5.3 0.1 5.9 5 0 0 5 5 5 2 Domain of unknown function (DUF4605) PsbL PF02419.17 OWF46256.1 - 0.017 15.1 0.2 1.7e+02 2.3 0.0 5.9 4 1 1 5 5 5 0 PsbL protein Antimicrobial10 PF08105.11 OWF46256.1 - 3.3 7.8 39.3 20 5.3 0.2 11.8 3 2 8 12 12 12 0 Metchnikowin family Ribosomal_L31e PF01198.19 OWF46257.1 - 1.7e-45 153.1 2.0 2.2e-45 152.8 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CopK PF11525.8 OWF46258.1 - 0.013 15.2 1.0 0.028 14.1 1.0 1.5 1 0 0 1 1 1 0 Copper resistance protein K zf-BED PF02892.15 OWF46259.1 - 0.0092 16.0 4.2 0.0092 16.0 4.2 2.9 3 0 0 3 3 3 1 BED zinc finger zf-C2H2_4 PF13894.6 OWF46259.1 - 0.017 15.9 19.8 0.2 12.6 4.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 OWF46259.1 - 0.02 15.2 1.7 0.02 15.2 1.7 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OWF46259.1 - 0.025 15.0 19.9 0.57 10.7 5.9 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type PyrI_C PF02748.15 OWF46259.1 - 0.085 12.8 2.3 1.5 8.8 0.3 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 OWF46259.1 - 2.5 8.8 10.5 2.5 8.8 0.2 3.4 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 OWF46259.1 - 2.7 8.7 10.2 3 8.5 0.6 3.6 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 OWF46260.1 - 1.5e-10 40.9 22.7 0.002 18.5 1.0 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 OWF46260.1 - 7.2e-07 29.4 16.7 0.014 15.8 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OWF46260.1 - 7.6e-07 29.5 30.2 0.014 16.2 1.9 4.8 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF46260.1 - 3.2e-05 24.1 23.7 0.064 13.6 0.5 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF46260.1 - 0.0014 18.5 29.9 0.003 17.5 1.6 4.4 4 1 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF46260.1 - 0.0059 17.0 29.8 0.26 11.8 1.9 4.9 4 1 0 4 4 4 2 Zinc-finger double domain BolA PF01722.18 OWF46260.1 - 0.054 13.8 1.1 8.8 6.7 0.0 3.1 1 1 2 3 3 3 0 BolA-like protein Desulfoferrod_N PF06397.12 OWF46260.1 - 0.12 12.1 0.5 0.12 12.1 0.5 2.8 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-C2HC_2 PF13913.6 OWF46260.1 - 0.26 11.3 15.2 0.42 10.6 0.2 4.2 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 OWF46260.1 - 0.91 9.7 7.4 2.5 8.3 2.9 2.7 2 1 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 OWF46260.1 - 0.93 10.2 14.6 5.7 7.6 8.3 3.0 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF2175 PF09943.9 OWF46260.1 - 2.2 8.6 6.6 1.2 9.4 0.7 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3449 PF11931.8 OWF46260.1 - 2.3 8.0 11.2 0.64 9.8 1.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3449) zf-Sec23_Sec24 PF04810.15 OWF46260.1 - 3 8.0 13.1 2.4 8.3 0.3 3.6 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-BED PF02892.15 OWF46260.1 - 6 7.0 14.2 3.4 7.8 0.8 3.3 2 1 1 3 3 3 0 BED zinc finger DUF629 PF04780.12 OWF46260.1 - 9 4.7 11.3 4.3 5.7 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 OWF46261.1 - 1.3e-08 35.0 23.4 0.00053 20.6 3.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 OWF46261.1 - 1.8e-08 34.2 10.0 0.0019 18.0 0.3 3.1 3 0 0 3 3 3 3 SprT-like zinc ribbon domain zf-C2H2 PF00096.26 OWF46261.1 - 2.3e-06 27.8 24.4 0.021 15.2 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF46261.1 - 1.1e-05 25.6 12.6 0.073 13.4 1.8 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF46261.1 - 2.8e-05 24.4 23.3 0.048 14.1 0.3 3.8 4 0 0 4 4 3 3 Zinc-finger double domain LIM PF00412.22 OWF46261.1 - 0.00036 20.7 5.1 0.00036 20.7 5.1 2.1 2 0 0 2 2 2 1 LIM domain zf-C2H2_6 PF13912.6 OWF46261.1 - 0.0011 18.9 26.5 0.014 15.4 3.2 4.1 3 1 1 4 4 4 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OWF46261.1 - 0.0018 18.3 9.7 0.05 13.7 4.2 2.8 1 1 2 3 3 3 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 OWF46261.1 - 0.021 14.6 18.5 0.69 9.7 1.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 OWF46261.1 - 0.065 13.7 1.0 0.065 13.7 1.0 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 OWF46261.1 - 0.07 12.7 9.4 1.1 9.0 1.4 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PyrI_C PF02748.15 OWF46261.1 - 0.17 11.9 0.8 0.17 11.9 0.8 3.0 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 OWF46261.1 - 0.19 12.1 12.9 0.79 10.1 1.8 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2757 PF10955.8 OWF46261.1 - 0.33 11.3 4.7 0.59 10.4 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) zf-MYST PF17772.1 OWF46261.1 - 0.36 10.5 0.1 0.36 10.5 0.1 2.9 3 1 0 3 3 3 0 MYST family zinc finger domain XPA_N PF01286.18 OWF46261.1 - 0.49 10.5 8.2 3.1 7.9 0.2 3.3 3 0 0 3 3 3 0 XPA protein N-terminal zf-met PF12874.7 OWF46261.1 - 0.61 10.5 14.0 2 8.9 1.6 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type HypA PF01155.19 OWF46261.1 - 0.62 10.1 5.8 9.2 6.3 5.8 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FCS PF06467.14 OWF46261.1 - 0.83 9.6 11.7 3.4 7.7 0.5 3.2 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.15 OWF46261.1 - 2.1 8.4 11.8 0.083 12.9 3.1 2.6 1 1 2 3 3 3 0 BED zinc finger FYVE PF01363.21 OWF46261.1 - 2.2 8.5 18.9 3.1 8.0 10.7 2.4 1 1 1 2 2 2 0 FYVE zinc finger Zf_RING PF16744.5 OWF46261.1 - 2.6 8.2 9.5 48 4.2 7.4 3.1 1 1 2 3 3 3 0 KIAA1045 RING finger Vps39_2 PF10367.9 OWF46261.1 - 2.9 8.4 7.9 5.8 7.4 3.8 2.6 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2 PF00096.26 OWF46262.1 - 1.7e-07 31.3 12.0 0.0022 18.3 4.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF46262.1 - 1.2e-06 28.9 10.2 0.001 19.7 1.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF46262.1 - 4.3e-06 26.9 6.2 0.0013 19.1 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF46262.1 - 7.5e-06 25.6 8.1 8e-06 25.5 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain A2L_zn_ribbon PF08792.10 OWF46262.1 - 4.1e-05 23.2 0.7 0.0064 16.2 0.1 2.6 2 0 0 2 2 2 1 A2L zinc ribbon domain zf-C2H2_11 PF16622.5 OWF46262.1 - 0.0022 17.7 1.5 0.0022 17.7 1.5 2.9 2 1 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 OWF46262.1 - 0.0023 17.7 4.3 0.49 10.3 0.3 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) Actin_micro PF17003.5 OWF46262.1 - 0.01 15.0 3.8 0.013 14.7 3.8 1.3 1 0 0 1 1 1 0 Putative actin-like family IBR PF01485.21 OWF46262.1 - 0.016 15.4 3.8 0.016 15.4 3.8 1.6 2 0 0 2 2 1 0 IBR domain, a half RING-finger domain Nudix_N_2 PF14803.6 OWF46262.1 - 0.03 14.2 2.9 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal GAGA PF09237.11 OWF46262.1 - 0.032 14.0 3.6 3.6 7.5 0.8 2.5 1 1 1 2 2 2 0 GAGA factor Zn-ribbon_8 PF09723.10 OWF46262.1 - 0.034 14.2 2.3 2.4 8.4 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 OWF46262.1 - 0.038 13.6 4.0 0.85 9.3 0.4 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 OWF46262.1 - 0.043 14.1 5.8 0.31 11.4 5.7 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2321 PF10083.9 OWF46262.1 - 0.046 13.4 1.2 0.059 13.0 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf_UBZ PF18439.1 OWF46262.1 - 0.066 12.8 2.1 1.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger betaPIX_CC PF16523.5 OWF46262.1 - 0.085 12.7 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 betaPIX coiled coil GFA PF04828.14 OWF46262.1 - 0.25 11.7 4.5 0.82 10.0 0.3 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rubredoxin_2 PF18073.1 OWF46262.1 - 0.43 10.3 3.0 4.6 7.1 0.4 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain OrfB_Zn_ribbon PF07282.11 OWF46262.1 - 0.73 9.8 7.1 0.94 9.4 0.8 2.9 1 1 2 3 3 3 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 OWF46263.1 - 4.9e-10 39.4 14.6 0.0029 17.9 1.3 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF46263.1 - 5.7e-10 39.2 23.8 0.0001 22.8 0.8 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF46263.1 - 2.9e-08 33.7 27.0 0.0021 18.4 0.8 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 OWF46263.1 - 5.2e-05 23.4 13.7 0.00099 19.4 6.2 2.9 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OWF46263.1 - 9.1e-05 22.7 7.7 0.2 12.1 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF46263.1 - 0.00059 19.8 1.0 0.00059 19.8 1.0 3.6 3 2 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF46263.1 - 0.0019 18.4 7.0 0.46 10.8 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 OWF46263.1 - 0.0048 16.9 8.7 0.025 14.6 3.4 2.7 1 1 1 2 2 2 1 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 OWF46263.1 - 0.0095 15.8 3.7 0.35 10.8 0.1 2.9 3 0 0 3 3 3 1 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 OWF46263.1 - 0.016 15.2 4.2 0.66 10.1 0.2 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Rad50_zn_hook PF04423.14 OWF46263.1 - 0.029 14.2 1.7 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_15 PF17032.5 OWF46263.1 - 0.033 14.9 4.5 0.17 12.7 1.6 2.1 1 1 1 2 2 2 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 OWF46263.1 - 0.038 14.5 0.2 0.038 14.5 0.2 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2197 PF09963.9 OWF46263.1 - 0.038 14.2 0.2 0.038 14.2 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-WRNIP1_ubi PF18279.1 OWF46263.1 - 0.04 14.6 0.5 0.12 13.1 0.1 2.1 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RRPl_C4 PF17026.5 OWF46263.1 - 0.055 13.6 2.2 0.079 13.1 2.2 1.3 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_11 PF16622.5 OWF46263.1 - 0.095 12.5 0.3 0.095 12.5 0.3 3.7 4 1 0 4 4 3 0 zinc-finger C2H2-type PHD PF00628.29 OWF46263.1 - 0.17 11.8 8.4 8.8 6.3 2.4 2.3 1 1 1 2 2 2 0 PHD-finger Zn-ribbon_8 PF09723.10 OWF46263.1 - 0.19 11.8 5.8 0.17 12.1 2.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 OWF46263.1 - 0.27 11.4 12.6 0.32 11.2 0.6 3.3 1 1 2 3 3 3 0 AN1-like Zinc finger zf-CHY PF05495.12 OWF46263.1 - 0.35 11.4 8.9 0.078 13.5 3.1 2.1 1 1 0 1 1 1 0 CHY zinc finger zf-C2H2_9 PF16293.5 OWF46263.1 - 0.66 9.9 0.2 0.66 9.9 0.2 2.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) CpXC PF14353.6 OWF46263.1 - 0.69 10.0 6.0 23 5.0 6.2 2.4 1 1 1 2 2 2 0 CpXC protein ADK_lid PF05191.14 OWF46263.1 - 0.74 9.9 4.8 1.7 8.7 1.0 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf_UBZ PF18439.1 OWF46263.1 - 1.8 8.3 8.7 4.4 7.0 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 OWF46263.1 - 2.7 7.7 11.6 0.21 11.2 2.8 2.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 OWF46263.1 - 4.6 7.5 11.8 7.7 6.7 10.7 1.9 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HE PF16278.5 OWF46263.1 - 7.1 7.2 11.1 4.1 7.9 5.0 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Actin_micro PF17003.5 OWF46263.1 - 8.1 5.5 8.1 93 2.0 8.1 2.1 1 1 0 1 1 1 0 Putative actin-like family zf-DNL PF05180.12 OWF46263.1 - 8.4 6.4 9.4 3.4 7.7 0.5 2.5 2 1 0 2 2 2 0 DNL zinc finger YiiD_C PF09500.10 OWF46264.1 - 0.065 13.1 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) Calreticulin PF00262.18 OWF46265.1 - 5.2e-161 535.6 17.0 8.3e-161 534.9 17.0 1.3 1 0 0 1 1 1 1 Calreticulin family MAP17 PF15807.5 OWF46265.1 - 0.00011 22.4 0.7 0.005 17.1 0.7 2.8 2 1 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CLN3 PF02487.17 OWF46265.1 - 0.0034 16.5 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 CLN3 protein SpoIIIAH PF12685.7 OWF46265.1 - 0.0048 16.8 1.0 0.0048 16.8 1.0 2.0 2 0 0 2 2 2 1 SpoIIIAH-like protein Connexin PF00029.19 OWF46265.1 - 0.024 14.4 4.3 0.2 11.4 4.3 2.3 1 1 0 1 1 1 0 Connexin SARAF PF06682.12 OWF46265.1 - 0.075 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Zip PF02535.22 OWF46265.1 - 0.088 12.0 1.3 0.17 11.0 1.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 OWF46265.1 - 0.27 10.0 0.0 0.47 9.2 0.0 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Orf78 PF06024.12 OWF46265.1 - 4.1 7.8 4.4 4.3 7.7 0.0 3.0 3 0 0 3 3 3 0 Orf78 (ac78) Herpes_UL6 PF01763.16 OWF46266.1 - 0.0028 16.3 0.0 0.0041 15.7 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like TSC22 PF01166.18 OWF46266.1 - 0.0053 17.0 0.0 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 TSC-22/dip/bun family Shisa PF13908.6 OWF46267.1 - 0.00012 22.4 0.1 0.00022 21.5 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FAM163 PF15069.6 OWF46267.1 - 0.0075 16.7 3.1 0.021 15.3 0.4 2.4 2 0 0 2 2 2 1 FAM163 family TMEM154 PF15102.6 OWF46267.1 - 0.053 13.4 0.2 0.053 13.4 0.2 2.0 2 1 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 OWF46267.1 - 0.13 13.2 0.1 0.45 11.4 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OWF46267.1 - 0.24 11.2 13.9 1.1 9.0 13.9 2.1 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Ank_2 PF12796.7 OWF46268.1 - 1.4e-36 125.0 0.0 2.9e-14 53.4 0.0 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF46268.1 - 2.9e-34 117.0 6.6 2.5e-09 37.5 0.0 6.2 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46268.1 - 2.6e-24 82.6 0.3 9.7e-05 22.5 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OWF46268.1 - 2.4e-23 81.9 0.2 1.8e-06 28.1 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 OWF46268.1 - 1.8e-22 79.9 17.4 1.8e-22 79.9 17.4 2.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.30 OWF46268.1 - 5.2e-18 64.6 0.1 0.0063 16.9 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat CCSMST1 PF15013.6 OWF46268.1 - 2.4 8.4 7.3 1.3 9.2 2.0 2.4 2 0 0 2 2 2 0 CCSMST1 family Ig_3 PF13927.6 OWF46270.1 - 0.0016 19.0 0.1 0.0029 18.1 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF46270.1 - 0.029 14.4 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF46270.1 - 0.034 14.5 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Mucin-like PF16058.5 OWF46271.1 - 9.7e-07 28.8 5.1 0.00078 19.5 0.2 2.7 2 1 1 3 3 3 2 Mucin-like Aldo_ket_red PF00248.21 OWF46272.1 - 1.2e-49 169.1 0.0 1.6e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 OWF46273.1 - 7.6e-45 153.3 0.0 1e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family VWD PF00094.25 OWF46274.1 - 6.4e-25 88.3 1.1 2.3e-24 86.5 0.3 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain TIL PF01826.17 OWF46274.1 - 3.5e-09 36.8 9.8 3.5e-09 36.8 9.8 6.0 4 2 2 6 6 6 2 Trypsin Inhibitor like cysteine rich domain C8 PF08742.11 OWF46274.1 - 5.2e-08 33.2 0.9 5.2e-08 33.2 0.9 3.6 3 1 0 3 3 3 1 C8 domain EGF_3 PF12947.7 OWF46274.1 - 0.0051 17.0 2.0 0.0051 17.0 2.0 7.1 6 1 2 8 8 8 2 EGF domain cEGF PF12662.7 OWF46274.1 - 0.059 13.3 0.8 0.059 13.3 0.8 5.6 5 0 0 5 5 5 0 Complement Clr-like EGF-like DPRP PF04244.13 OWF46274.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein EB PF01683.18 OWF46275.1 - 2.8e-06 27.5 373.9 0.37 11.1 5.8 25.6 8 7 17 25 25 25 20 EB module EGF_MSP1_1 PF12946.7 OWF46275.1 - 0.011 15.8 8.5 0.011 15.8 8.5 25.9 25 0 0 25 25 25 0 MSP1 EGF domain 1 PDEase_I PF00233.19 OWF46276.1 - 1.7e-75 253.8 6.5 1.7e-75 253.8 6.5 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OWF46276.1 - 3.3e-26 92.5 0.0 3.4e-15 56.9 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 OWF46276.1 - 7.3e-23 81.4 0.0 3.6e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 OWF46276.1 - 2.4e-09 37.6 0.0 2.1e-05 24.9 0.0 3.0 3 0 0 3 3 3 2 GAF domain M16C_assoc PF08367.11 OWF46276.1 - 0.017 14.3 1.2 0.39 9.8 0.2 2.4 2 0 0 2 2 2 0 Peptidase M16C associated AnmK PF03702.14 OWF46277.1 - 1.9e-52 178.6 0.0 2.5e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase MreB_Mbl PF06723.13 OWF46277.1 - 0.036 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein LRRC37AB_C PF14914.6 OWF46277.1 - 0.2 11.5 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain zf-B_box PF00643.24 OWF46278.1 - 4.7e-07 29.9 8.6 1.1e-06 28.7 8.6 1.6 1 0 0 1 1 1 1 B-box zinc finger NHL PF01436.21 OWF46278.1 - 5.8e-05 22.9 6.2 0.026 14.5 0.3 4.1 3 0 0 3 3 3 3 NHL repeat Erf4 PF10256.9 OWF46279.1 - 2e-10 40.8 0.0 2.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family YiiD_C PF09500.10 OWF46279.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) Homeodomain PF00046.29 OWF46280.1 - 3.8e-21 74.7 2.9 7e-21 73.8 2.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF46280.1 - 0.0013 18.6 0.2 0.0036 17.2 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain tRNA_bind_2 PF13725.6 OWF46280.1 - 0.0091 15.7 1.0 0.0091 15.7 1.0 1.6 2 0 0 2 2 2 1 Possible tRNA binding domain DUF4510 PF14971.6 OWF46280.1 - 0.33 11.3 2.1 1.3 9.3 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) Glyco_transf_7C PF02709.14 OWF46281.1 - 1.2e-24 85.8 0.1 2.4e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 OWF46281.1 - 1.2e-22 80.0 0.3 1.8e-22 79.4 0.3 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 OWF46281.1 - 0.047 13.2 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF46282.1 - 1.9e-25 88.3 0.2 3.7e-25 87.4 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 OWF46282.1 - 2.4e-22 79.0 0.4 3.2e-22 78.6 0.4 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 OWF46282.1 - 0.019 14.5 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 MFS_1 PF07690.16 OWF46283.1 - 6.5e-54 183.2 26.9 4.9e-51 173.7 29.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF46283.1 - 4.9e-08 32.3 24.0 5.4e-07 28.8 23.0 2.6 1 1 2 3 3 3 1 Sugar (and other) transporter tRNA-synt_2c PF01411.19 OWF46284.1 - 1.4e-162 542.1 0.1 2e-162 541.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OWF46284.1 - 7.9e-11 41.9 0.5 2.5e-10 40.3 0.1 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF896 PF05979.12 OWF46284.1 - 0.018 14.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) zf-MYST PF17772.1 OWF46284.1 - 0.072 12.7 1.5 0.17 11.5 1.5 1.6 1 0 0 1 1 1 0 MYST family zinc finger domain Phasin PF05597.11 OWF46284.1 - 0.15 12.1 2.4 2.2 8.3 0.6 2.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tape_meas_lam_C PF09718.10 OWF46284.1 - 0.19 11.9 0.4 0.7 10.1 0.2 2.0 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Spectrin PF00435.21 OWF46285.1 - 3.2e-267 866.5 170.3 8e-25 87.4 5.2 16.3 16 0 0 16 16 16 15 Spectrin repeat CH PF00307.31 OWF46285.1 - 1.3e-47 160.5 4.7 1.1e-25 89.9 0.1 4.2 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OWF46285.1 - 1.3e-07 31.4 0.0 1.9e-05 24.4 0.0 3.0 2 0 0 2 2 2 1 CAMSAP CH domain DUF5616 PF18481.1 OWF46285.1 - 0.052 13.9 3.7 2.9 8.2 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF5616) SesA PF17107.5 OWF46285.1 - 4.5 7.5 17.9 0.18 12.0 0.2 5.6 5 1 0 5 5 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HisKA_2 PF07568.12 OWF46285.1 - 7.6 6.7 8.1 4.3 7.5 0.1 4.2 4 0 0 4 4 4 0 Histidine kinase Vps39_1 PF10366.9 OWF46286.1 - 4.2e-33 113.8 1.0 4.2e-33 113.8 1.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 OWF46286.1 - 4.9e-31 107.4 2.9 4.9e-31 107.4 2.9 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OWF46286.1 - 2.2e-25 89.8 0.1 5e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 OWF46286.1 - 1.3e-12 47.8 16.7 5.4e-05 23.1 0.2 4.5 3 2 1 4 4 4 3 Region in Clathrin and VPS DHC PF09626.10 OWF46286.1 - 0.061 14.2 1.1 0.72 10.7 0.7 2.7 2 0 0 2 2 2 0 Dihaem cytochrome c WD40 PF00400.32 OWF46287.1 - 2.3e-18 66.2 7.1 0.00069 20.4 0.3 6.2 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3991 PF13154.6 OWF46287.1 - 0.05 14.0 0.0 3 8.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) BBS2_Mid PF14783.6 OWF46287.1 - 0.12 12.4 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 OWF46287.1 - 0.13 12.6 0.1 2.9 8.3 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M8 PF01457.16 OWF46288.1 - 5.8e-30 104.5 9.2 6.7e-21 74.6 1.3 2.3 1 1 1 2 2 2 2 Leishmanolysin DUF4611 PF15387.6 OWF46289.1 - 8.4e-07 29.1 1.0 1e-06 28.9 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Gon7 PF08738.10 OWF46289.1 - 0.0081 16.2 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Gon7 family Spt5_N PF11942.8 OWF46289.1 - 0.11 13.5 6.0 0.18 12.8 6.0 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Asparaginase_2 PF01112.18 OWF46291.1 - 9.8e-108 359.8 8.5 1.2e-107 359.5 8.5 1.0 1 0 0 1 1 1 1 Asparaginase Rep_1B PF17873.1 OWF46291.1 - 0.094 12.6 1.6 0.29 11.0 0.1 2.6 2 0 0 2 2 2 0 Replicase polyprotein 1ab MBD PF01429.19 OWF46292.1 - 5.5e-11 42.0 0.0 1.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain F-box-like PF12937.7 OWF46292.1 - 5.6e-09 35.8 1.3 1.2e-08 34.7 1.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF46292.1 - 6.4e-07 29.1 0.5 2.2e-06 27.4 0.5 1.9 1 0 0 1 1 1 1 F-box domain DUF824 PF05688.11 OWF46292.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) LRR_4 PF12799.7 OWF46292.1 - 0.99 9.9 7.9 0.55 10.7 0.1 4.4 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) PHD PF00628.29 OWF46292.1 - 1.6 8.7 8.9 3.6 7.5 8.9 1.6 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 OWF46292.1 - 3 7.5 6.1 6.4 6.4 6.1 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 OWF46293.1 - 3.1e-10 39.9 3.3 3.1e-10 39.9 3.3 3.9 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF46293.1 - 2.1e-08 33.9 6.1 2.1e-08 33.9 6.1 3.9 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF46293.1 - 1.7e-07 31.4 6.0 1.7e-07 31.4 6.0 3.7 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF46293.1 - 1.6e-06 27.8 3.1 1.6e-06 27.8 3.1 4.6 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF46293.1 - 2e-06 27.6 4.7 2e-06 27.6 4.7 3.6 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF46293.1 - 9.5e-06 25.7 8.9 9.5e-06 25.7 8.9 3.1 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF46293.1 - 1.3e-05 25.0 5.6 1.3e-05 25.0 5.6 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF46293.1 - 0.001 19.0 1.4 25 5.1 0.2 4.8 4 0 0 4 4 4 0 NHL repeat SBBP PF06739.11 OWF46293.1 - 0.0024 17.8 0.1 0.007 16.3 0.1 1.7 1 0 0 1 1 1 1 Beta-propeller repeat Cut12 PF11500.8 OWF46293.1 - 0.0064 16.5 3.1 0.013 15.4 3.1 1.4 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Prok-RING_4 PF14447.6 OWF46293.1 - 0.0072 16.2 6.2 0.0072 16.2 6.2 2.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SGL PF08450.12 OWF46293.1 - 0.013 15.1 1.6 0.45 10.0 0.1 3.2 2 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region ANXA2R PF15721.5 OWF46293.1 - 0.053 14.0 0.2 0.13 12.8 0.0 1.6 2 0 0 2 2 1 0 Annexin-2 receptor Snapin_Pallidin PF14712.6 OWF46293.1 - 0.44 11.0 5.9 1.1 9.8 5.9 1.7 1 0 0 1 1 1 0 Snapin/Pallidin L1R_F9L PF02442.17 OWF46293.1 - 2.3 8.1 14.8 0.1 12.4 8.5 2.0 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Antifungal_prot PF11402.8 OWF46294.1 - 0.053 13.8 3.8 4.7 7.5 1.0 2.3 2 0 0 2 2 2 0 Antifungal protein zf-CCCH PF00642.24 OWF46294.1 - 0.22 11.5 7.6 0.67 9.9 3.7 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OWF46294.1 - 2.2 8.2 8.1 2.5 8.0 2.9 2.8 2 2 0 2 2 2 0 CCCH-type zinc finger 7tm_1 PF00001.21 OWF46295.1 - 2e-22 79.8 14.4 2.5e-22 79.5 14.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF46295.1 - 0.0018 18.0 16.6 0.0081 15.8 16.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx BBS2_Mid PF14783.6 OWF46296.1 - 0.032 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Ion_trans_2 PF07885.16 OWF46297.1 - 6e-35 119.1 28.3 1.8e-18 66.3 4.1 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF46297.1 - 2.1e-08 33.7 13.9 3.4e-06 26.5 0.7 2.2 2 0 0 2 2 2 2 Ion transport protein Pex24p PF06398.11 OWF46297.1 - 4.8e-06 25.8 0.3 0.0027 16.8 0.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Senescence PF06911.12 OWF46297.1 - 0.00081 19.8 4.6 0.0016 18.8 4.6 1.5 1 0 0 1 1 1 1 Senescence-associated protein Apolipoprotein PF01442.18 OWF46297.1 - 0.0034 17.3 2.2 0.01 15.8 2.2 1.7 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Spore_III_AF PF09581.10 OWF46297.1 - 0.0063 16.6 0.9 0.0063 16.6 0.9 3.2 3 2 0 3 3 2 1 Stage III sporulation protein AF (Spore_III_AF) DUF1043 PF06295.12 OWF46297.1 - 0.012 15.6 0.9 0.72 9.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ApoLp-III PF07464.11 OWF46297.1 - 0.02 15.0 7.2 0.02 15.0 7.2 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Folate_carrier PF01770.18 OWF46297.1 - 0.021 13.6 2.4 2.5 6.7 0.5 2.3 2 0 0 2 2 2 0 Reduced folate carrier Sds3 PF08598.11 OWF46297.1 - 0.023 14.7 3.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Sds3-like LXG PF04740.12 OWF46297.1 - 0.026 14.2 8.2 0.18 11.5 2.8 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily 7tm_1 PF00001.21 OWF46297.1 - 0.037 13.4 0.0 0.097 12.0 0.0 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ctr PF04145.15 OWF46297.1 - 0.054 14.1 0.1 32 5.1 0.0 3.3 2 1 1 3 3 3 0 Ctr copper transporter family RmuC PF02646.16 OWF46297.1 - 0.067 12.3 4.5 0.17 11.0 4.5 1.6 1 0 0 1 1 1 0 RmuC family Exonuc_VII_L PF02601.15 OWF46297.1 - 0.093 12.3 1.3 0.29 10.6 0.2 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Uds1 PF15456.6 OWF46297.1 - 0.1 12.7 6.7 6.3 7.0 4.2 2.5 2 0 0 2 2 2 0 Up-regulated During Septation DUF4446 PF14584.6 OWF46297.1 - 0.12 12.4 9.1 0.69 9.9 3.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) SOAR PF16533.5 OWF46297.1 - 0.13 12.2 5.6 0.43 10.6 5.6 1.9 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF3974 PF13120.6 OWF46297.1 - 0.14 12.3 0.7 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) tRNA_bind_2 PF13725.6 OWF46297.1 - 0.16 11.6 7.4 0.46 10.1 7.4 1.7 1 0 0 1 1 1 0 Possible tRNA binding domain TssO PF17561.2 OWF46297.1 - 0.23 11.5 7.3 0.24 11.5 2.4 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO Sensor PF13796.6 OWF46297.1 - 0.25 11.4 1.0 36 4.4 0.0 3.2 3 0 0 3 3 3 0 Putative sensor Atg14 PF10186.9 OWF46297.1 - 0.26 10.3 3.6 1.2 8.1 0.9 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM176 PF14851.6 OWF46297.1 - 0.27 10.9 3.4 2.1 8.0 0.0 3.0 3 1 1 4 4 4 0 FAM176 family Prominin PF05478.11 OWF46297.1 - 0.49 8.3 6.7 0.7 7.8 4.2 2.1 2 0 0 2 2 2 0 Prominin T3SS_basalb_I PF17001.5 OWF46297.1 - 0.67 10.6 8.2 0.17 12.5 4.2 2.0 2 0 0 2 2 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI RRF PF01765.19 OWF46297.1 - 2 8.3 20.1 0.11 12.4 14.3 1.8 2 0 0 2 2 2 0 Ribosome recycling factor MIF4G_like_2 PF09090.11 OWF46297.1 - 2 7.8 6.7 5.1 6.5 6.7 1.6 1 0 0 1 1 1 0 MIF4G like DUF883 PF05957.13 OWF46297.1 - 2.2 8.9 5.9 12 6.6 5.9 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) EspB PF05802.11 OWF46297.1 - 5 7.1 10.0 0.4 10.6 4.8 1.8 2 0 0 2 2 2 0 Enterobacterial EspB protein Nup54 PF13874.6 OWF46297.1 - 6.7 6.8 7.7 0.81 9.8 2.2 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.12 OWF46297.1 - 7.8 6.6 13.0 0.34 10.9 5.7 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) TPR_12 PF13424.6 OWF46298.1 - 0.0062 16.8 3.2 0.0062 16.8 3.2 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Phage_term_smal PF05944.12 OWF46298.1 - 0.021 14.8 0.8 0.085 12.8 0.1 2.4 2 0 0 2 2 2 0 Phage small terminase subunit SYCP2_ARLD PF18581.1 OWF46298.1 - 0.64 10.0 4.7 0.9 9.5 0.3 2.8 2 1 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain TetR_C_30 PF17939.1 OWF46298.1 - 0.65 10.2 4.2 15 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain GFO_IDH_MocA PF01408.22 OWF46300.1 - 3.5e-27 95.6 0.0 5.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OWF46300.1 - 0.00029 21.5 0.0 0.00051 20.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OWF46300.1 - 0.0024 18.0 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ank_5 PF13857.6 OWF46301.1 - 8.1e-108 351.1 35.7 2.1e-11 43.8 1.0 15.2 6 5 9 15 15 15 15 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF46301.1 - 1.8e-103 339.3 25.4 2.3e-13 50.6 0.3 11.0 5 3 7 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF46301.1 - 2.1e-103 337.5 38.0 5.8e-12 45.9 0.1 16.0 6 5 12 19 19 19 18 Ankyrin repeats (many copies) Ank PF00023.30 OWF46301.1 - 9.4e-102 329.4 40.4 4.7e-07 30.0 0.0 19.0 19 0 0 19 19 19 15 Ankyrin repeat Ank_3 PF13606.6 OWF46301.1 - 1e-96 305.1 28.7 1.2e-06 28.3 0.0 20.2 22 0 0 22 22 22 16 Ankyrin repeat PARP PF00644.20 OWF46301.1 - 8.6e-27 94.0 2.0 1.8e-24 86.5 2.0 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 OWF46301.1 - 2.7e-14 53.0 0.1 5.9e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF46301.1 - 4.3e-14 52.7 0.3 1.1e-13 51.4 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5521 PF17659.1 OWF46301.1 - 0.035 12.0 0.0 0.099 10.5 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5521) bZIP_1 PF00170.21 OWF46302.1 - 0.0015 18.6 8.9 0.0033 17.5 8.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF46302.1 - 0.31 11.1 4.4 0.7 10.0 4.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper PI3_PI4_kinase PF00454.27 OWF46303.1 - 4.9e-58 196.9 0.0 6e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Toxin_16 PF07945.11 OWF46303.1 - 0.073 13.0 5.2 0.13 12.1 5.2 1.3 1 0 0 1 1 1 0 Janus-atracotoxin FF PF01846.19 OWF46304.1 - 1e-62 208.1 55.2 6.6e-14 51.8 4.5 6.5 6 0 0 6 6 6 6 FF domain WW PF00397.26 OWF46304.1 - 1e-22 79.9 13.2 3.8e-07 30.1 1.2 3.9 3 0 0 3 3 3 3 WW domain RhoGAP-FF1 PF16512.5 OWF46304.1 - 2e-05 25.2 20.1 0.00055 20.6 1.3 4.8 2 2 1 4 4 4 2 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 OWF46304.1 - 0.17 12.2 12.0 1.2 9.4 0.8 3.8 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Glyco_hydro_20 PF00728.22 OWF46305.1 - 9.6e-11 41.7 0.4 2e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Macro PF01661.21 OWF46306.1 - 9.7e-25 86.9 0.0 1.9e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Macro domain IL11 PF07400.11 OWF46306.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Interleukin 11 DUF3357 PF11837.8 OWF46307.1 - 0.016 15.6 0.1 0.043 14.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PLA2_B PF01735.18 OWF46308.1 - 9e-79 265.1 0.0 6.1e-78 262.4 0.0 1.9 1 1 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.30 OWF46308.1 - 6.5e-13 48.9 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF4637 PF15470.6 OWF46308.1 - 2.1 8.1 6.2 6.7 6.4 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 OWF46308.1 - 3.2 5.9 8.7 5 5.3 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_1 PF00583.25 OWF46309.1 - 2.9e-13 50.1 0.0 5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF46309.1 - 1.3e-06 28.7 0.0 2.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF46309.1 - 6.4e-06 26.1 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF46309.1 - 0.00017 21.5 0.0 0.00047 20.1 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OWF46309.1 - 0.0016 18.5 0.0 0.0046 17.1 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 OWF46309.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Mating_N PF12731.7 OWF46309.1 - 0.046 13.8 0.2 0.42 10.7 0.0 2.8 4 1 0 4 4 4 0 Mating-type protein beta 1 Baculo_PEP_C PF04513.12 OWF46309.1 - 0.061 13.4 5.3 2.1 8.4 0.2 3.3 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus EcsC PF12787.7 OWF46309.1 - 0.07 12.8 0.1 0.33 10.6 0.0 1.9 1 1 0 2 2 2 0 EcsC protein family Prominin PF05478.11 OWF46309.1 - 0.24 9.3 0.0 0.34 8.8 0.0 1.2 1 0 0 1 1 1 0 Prominin DUF1043 PF06295.12 OWF46309.1 - 0.24 11.4 2.2 0.6 10.1 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) TetR_C_37 PF18665.1 OWF46310.1 - 0.11 13.1 0.2 5.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Baculo_PEP_C PF04513.12 OWF46310.1 - 0.15 12.1 0.3 3.4 7.7 0.0 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLLAC PF15675.5 OWF46310.1 - 0.42 10.2 2.2 0.89 9.2 2.2 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain SseB PF07179.12 OWF46311.1 - 0.031 14.6 0.1 41 4.4 0.0 3.2 2 1 1 3 3 3 0 SseB protein N-terminal domain GRIP PF01465.20 OWF46311.1 - 0.044 13.7 0.1 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 GRIP domain TMEM51 PF15345.6 OWF46314.1 - 0.0014 18.6 0.0 0.0015 18.4 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 SKG6 PF08693.10 OWF46314.1 - 0.0037 16.6 2.5 0.0037 16.6 2.5 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OWF46314.1 - 0.02 14.8 0.8 0.068 13.1 0.8 1.9 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 OWF46314.1 - 0.028 15.3 0.0 0.034 15.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.12 OWF46314.1 - 0.032 14.4 0.2 0.05 13.8 0.2 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF5129 PF17173.4 OWF46314.1 - 0.043 12.9 0.1 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) F5_F8_type_C PF00754.25 OWF46315.1 - 2.3e-09 37.4 0.5 2.9e-09 37.1 0.5 1.1 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 OWF46316.1 - 8e-09 35.7 2.2 1.4e-08 34.9 2.2 1.4 1 0 0 1 1 1 1 F5/8 type C domain EphA2_TM PF14575.6 OWF46316.1 - 0.11 13.4 0.0 0.39 11.6 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 OWF46316.1 - 0.21 11.4 0.6 0.3 10.9 0.0 1.4 2 0 0 2 2 2 0 Transmembrane protein 51 Laminin_EGF PF00053.24 OWF46316.1 - 0.72 10.0 206.6 0.06 13.5 13.3 13.0 3 1 11 14 14 14 0 Laminin EGF domain Bromo_TP PF07524.13 OWF46317.1 - 0.048 13.7 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Y_phosphatase PF00102.27 OWF46319.1 - 6.4e-119 395.7 1.7 8.3e-72 241.5 0.1 2.6 3 0 0 3 3 3 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 OWF46319.1 - 3.9e-08 33.5 0.6 1.1e-07 32.1 0.3 1.8 2 0 0 2 2 2 1 F5/8 type C domain Laminin_EGF PF00053.24 OWF46319.1 - 1.3e-07 31.7 126.6 0.3 11.3 14.1 9.5 1 1 7 8 8 8 5 Laminin EGF domain SKG6 PF08693.10 OWF46319.1 - 0.00049 19.4 3.3 0.0011 18.3 3.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DSPc PF00782.20 OWF46319.1 - 0.00087 19.1 0.1 0.36 10.6 0.0 3.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain EphA2_TM PF14575.6 OWF46319.1 - 0.0062 17.4 0.0 0.032 15.1 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain PTPlike_phytase PF14566.6 OWF46319.1 - 0.031 14.4 0.1 0.35 11.0 0.0 2.7 3 0 0 3 3 3 0 Inositol hexakisphosphate Podoplanin PF05808.11 OWF46319.1 - 0.04 14.0 1.6 0.095 12.8 1.6 1.5 1 0 0 1 1 1 0 Podoplanin Y_phosphatase3 PF13350.6 OWF46319.1 - 0.14 12.1 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family HlyD_D4 PF16572.5 OWF46320.1 - 0.028 14.3 0.2 4 7.4 0.0 3.1 1 1 3 4 4 4 0 Long alpha hairpin domain of cation efflux system protein, CusB DUF2574 PF10836.8 OWF46320.1 - 0.092 12.6 0.8 50 3.9 0.1 3.1 1 1 2 4 4 4 0 Protein of unknown function (DUF2574) TF_AP-2 PF03299.14 OWF46321.1 - 5.4e-84 281.1 0.0 7.1e-84 280.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 Med31 PF05669.12 OWF46323.1 - 0.00085 19.3 7.9 7.2 6.7 7.9 4.0 1 1 0 1 1 1 1 SOH1 CoiA PF06054.11 OWF46323.1 - 0.0022 17.2 15.9 0.36 9.9 4.4 2.9 1 1 2 3 3 3 3 Competence protein CoiA-like family Polysacc_deac_2 PF04748.13 OWF46323.1 - 0.018 14.2 9.0 1.1 8.3 0.7 3.0 1 1 2 3 3 3 0 Divergent polysaccharide deacetylase LPD34 PF18852.1 OWF46323.1 - 0.095 12.3 27.1 1.8e+04 -10.5 27.1 4.7 1 1 0 1 1 1 0 Large polyvalent protein associated domain 34 PhoPQ_related PF10142.9 OWF46323.1 - 2.9 6.4 18.4 4.7 5.8 4.0 2.7 1 1 1 2 2 2 0 PhoPQ-activated pathogenicity-related protein DUF1761 PF08570.10 OWF46324.1 - 0.25 11.6 23.7 13 6.0 8.4 3.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1761) MFS_1 PF07690.16 OWF46325.1 - 1.8e-51 175.2 27.9 1.8e-51 175.2 27.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily ATP11 PF06644.11 OWF46326.1 - 1.1e-43 150.0 8.0 3.8e-43 148.2 8.0 1.7 1 1 0 1 1 1 1 ATP11 protein EGF PF00008.27 OWF46327.1 - 2.6e-135 440.1 443.9 1.8e-09 37.7 11.6 29.5 29 0 0 29 29 29 28 EGF-like domain hEGF PF12661.7 OWF46327.1 - 6.9e-64 210.5 366.0 0.00012 22.6 4.7 31.2 29 1 0 29 29 29 26 Human growth factor-like EGF EGF_2 PF07974.13 OWF46327.1 - 7.3e-34 115.8 497.1 8.8e-05 22.8 6.8 29.6 29 1 0 29 29 29 25 EGF-like domain EGF_CA PF07645.15 OWF46327.1 - 0.00011 22.3 23.2 0.00095 19.3 6.5 29.3 8 7 21 29 29 29 13 Calcium-binding EGF domain DUF2576 PF10845.8 OWF46327.1 - 0.2 11.3 3.1 1.5 8.5 3.1 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) FA_hydroxylase PF04116.13 OWF46328.1 - 1.3e-15 57.9 15.9 1.3e-15 57.9 15.9 2.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily WAP PF00095.21 OWF46330.1 - 1.3e-18 67.1 39.7 4.4e-11 43.0 16.4 3.3 3 1 0 3 3 3 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF4555 PF15093.6 OWF46331.1 - 2.2e-62 210.9 1.5 4.9e-62 209.8 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4555) CP2 PF04516.15 OWF46332.1 - 1.1e-62 211.3 0.1 2.8e-62 210.0 0.1 1.5 1 1 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 OWF46332.1 - 1.5e-15 56.7 0.0 3.7e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_6 PF13516.6 OWF46333.1 - 5.3e-22 75.9 19.4 0.0014 18.5 0.1 10.3 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 OWF46333.1 - 1.9e-13 50.4 13.1 0.0033 17.8 0.2 6.7 4 2 0 6 6 6 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OWF46333.1 - 8.7e-12 44.7 0.6 2.5e-11 43.3 0.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 OWF46333.1 - 7.8e-07 28.8 27.8 14 6.7 0.0 10.8 10 1 0 10 10 10 1 Leucine Rich Repeat F-box PF00646.33 OWF46333.1 - 5.8e-06 26.1 0.7 2e-05 24.3 0.7 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OWF46333.1 - 0.0037 17.1 0.5 0.019 14.9 0.0 2.4 3 0 0 3 3 3 1 F-box PTE PF02126.18 OWF46333.1 - 0.13 11.6 0.0 7.9 5.8 0.0 2.8 1 1 1 2 2 2 0 Phosphotriesterase family QslA_E PF18226.1 OWF46334.1 - 0.27 11.2 6.9 8.5 6.4 0.4 3.4 1 1 2 3 3 3 0 LasR-specific antiactivator QslA chain E DUF4124 PF13511.6 OWF46334.1 - 0.98 9.8 8.6 49 4.4 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4124) FCH PF00611.23 OWF46335.1 - 3e-18 65.9 0.5 3e-18 65.9 0.5 3.5 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 OWF46335.1 - 3.4e-07 29.8 0.0 6.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF46335.1 - 0.00014 21.7 0.2 0.00081 19.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 OWF46335.1 - 0.0037 17.5 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Rx_N PF18052.1 OWF46335.1 - 0.1 12.9 2.7 0.16 12.2 0.0 2.5 2 1 0 2 2 2 0 Rx N-terminal domain Syntaxin-6_N PF09177.11 OWF46335.1 - 7 7.3 10.2 14 6.3 6.1 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PIN_2 PF10130.9 OWF46336.1 - 0.19 12.0 3.1 0.88 9.8 3.3 1.9 2 0 0 2 2 2 0 PIN domain LPMO_10 PF03067.15 OWF46337.1 - 3.4e-24 86.6 0.0 3.4e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Mucin PF01456.17 OWF46337.1 - 0.12 12.4 36.8 0.23 11.4 36.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 OWF46337.1 - 0.14 10.2 8.2 0.21 9.7 8.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LPMO_10 PF03067.15 OWF46338.1 - 2.6e-08 34.8 0.0 3.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SlyX PF04102.12 OWF46338.1 - 0.00096 19.7 9.7 0.25 12.0 2.3 3.0 1 1 2 3 3 3 3 SlyX Laminin_II PF06009.12 OWF46338.1 - 0.0021 18.1 14.0 0.037 14.0 2.6 2.3 1 1 1 2 2 2 2 Laminin Domain II Apo-CIII PF05778.12 OWF46338.1 - 0.0047 16.5 2.4 11 5.7 0.0 4.3 1 1 5 6 6 6 1 Apolipoprotein CIII (Apo-CIII) Atg14 PF10186.9 OWF46338.1 - 0.0075 15.4 4.5 0.074 12.1 4.5 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 OWF46338.1 - 0.014 15.8 2.2 28 5.2 1.7 3.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 OWF46338.1 - 0.064 13.3 8.4 0.2 11.7 1.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 OWF46338.1 - 0.28 11.2 4.0 7.1 6.7 0.2 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain TTKRSYEDQ PF10212.9 OWF46338.1 - 0.74 8.7 14.4 1.1 8.2 2.2 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF16 PF01519.16 OWF46338.1 - 1.2 9.7 3.0 16 6.0 3.0 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 Sbi-IV PF11621.8 OWF46338.1 - 1.4 9.4 8.9 52 4.3 0.2 4.3 1 1 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Swi5 PF07061.11 OWF46338.1 - 3.9 7.6 5.5 6.8 6.9 0.6 2.6 1 1 1 2 2 2 0 Swi5 NPV_P10 PF05531.12 OWF46338.1 - 5.9 7.4 19.1 26 5.4 6.0 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein NBP1 PF08537.10 OWF46338.1 - 7.1 5.9 29.8 3.2 7.1 10.9 2.3 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 Tropomyosin_1 PF12718.7 OWF46338.1 - 8.1 6.6 7.4 9.7 6.3 5.9 1.7 1 1 0 1 1 1 0 Tropomyosin like zf-B_box PF00643.24 OWF46339.1 - 2.3e-11 43.7 19.4 1.8e-08 34.4 7.2 2.5 2 1 0 2 2 2 2 B-box zinc finger ZZ PF00569.17 OWF46339.1 - 0.03 14.1 4.6 0.03 14.1 4.6 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type Fez1 PF06818.15 OWF46339.1 - 0.079 13.4 3.4 0.13 12.7 3.4 1.3 1 0 0 1 1 1 0 Fez1 DUF1640 PF07798.11 OWF46339.1 - 0.16 12.0 5.9 0.22 11.6 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 OWF46339.1 - 0.17 11.9 3.1 0.29 11.2 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 OWF46339.1 - 0.17 12.4 5.0 0.28 11.7 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Pkinase PF00069.25 OWF46340.1 - 2.2e-72 243.6 0.0 2.5e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF46340.1 - 6.2e-32 110.9 0.0 8.3e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF46340.1 - 2.9e-07 29.8 0.2 4.3e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OWF46340.1 - 0.00051 19.4 0.2 0.1 11.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 OWF46340.1 - 0.049 13.2 1.0 0.19 11.3 1.0 1.8 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 OWF46340.1 - 0.051 12.3 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase BTB PF00651.31 OWF46341.1 - 1.2e-20 73.8 0.1 7.5e-15 55.1 0.0 3.6 4 0 0 4 4 4 2 BTB/POZ domain BACK PF07707.15 OWF46341.1 - 0.00055 20.0 2.1 0.3 11.2 0.0 3.0 3 0 0 3 3 3 2 BTB And C-terminal Kelch CAP PF00188.26 OWF46342.1 - 6.5e-41 140.1 7.4 1.3e-20 74.5 0.3 3.4 3 0 0 3 3 3 2 Cysteine-rich secretory protein family IFT46_B_C PF12317.8 OWF46342.1 - 0.052 13.3 0.2 0.052 13.3 0.2 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal zf-B_box PF00643.24 OWF46343.1 - 4.4e-12 46.0 23.1 2e-07 31.0 5.3 2.7 2 1 0 2 2 2 2 B-box zinc finger DUF1640 PF07798.11 OWF46343.1 - 0.085 12.9 6.6 0.14 12.2 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DLP_helical PF18709.1 OWF46343.1 - 0.13 11.5 4.2 0.2 10.8 4.2 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain FlgD_ig PF13860.6 OWF46343.1 - 0.14 12.0 0.1 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 FlgD Ig-like domain SF-assemblin PF06705.11 OWF46343.1 - 0.21 10.9 9.3 0.35 10.2 9.3 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Med11 PF10280.9 OWF46343.1 - 0.24 11.9 4.3 0.8 10.2 4.3 1.8 1 1 0 1 1 1 0 Mediator complex protein Sec20 PF03908.13 OWF46343.1 - 0.55 10.2 3.1 11 6.0 0.1 2.7 3 0 0 3 3 3 0 Sec20 OmpH PF03938.14 OWF46343.1 - 0.97 9.8 7.9 0.77 10.1 6.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 OWF46343.1 - 1.5 9.3 11.3 2.3 8.6 11.3 1.2 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 OWF46343.1 - 4.2 7.4 12.9 0.83 9.7 3.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5401 PF17380.2 OWF46344.1 - 0.75 7.8 3.0 0.86 7.6 3.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RRM_1 PF00076.22 OWF46345.1 - 2.1e-08 33.9 0.1 4.8e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAP_assoc PF03828.19 OWF46345.1 - 8.4e-07 29.1 0.1 2.1e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-C2H2_jaz PF12171.8 OWF46345.1 - 2.5e-05 24.4 1.2 3.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF46345.1 - 8e-05 22.9 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Mucin PF01456.17 OWF46345.1 - 0.087 12.8 6.3 0.16 12.0 6.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_7 PF16367.5 OWF46345.1 - 0.088 12.9 0.0 0.86 9.8 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif DUF4175 PF13779.6 OWF46345.1 - 3.3 5.5 7.6 6 4.7 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zona_pellucida PF00100.23 OWF46347.1 - 8.4e-15 55.3 0.9 1.3e-14 54.6 0.9 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain EGF_2 PF07974.13 OWF46347.1 - 0.0025 18.1 28.8 0.035 14.5 10.1 3.0 2 0 0 2 2 2 2 EGF-like domain TMEM154 PF15102.6 OWF46347.1 - 0.017 15.1 0.3 0.033 14.1 0.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 OWF46347.1 - 1.3 9.9 3.6 5.6 7.9 1.8 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain hEGF PF12661.7 OWF46347.1 - 1.9 9.3 23.8 2.3 9.0 8.0 3.2 3 0 0 3 3 3 0 Human growth factor-like EGF EGF PF00008.27 OWF46347.1 - 4.2 7.8 28.6 0.27 11.6 9.8 3.2 3 0 0 3 3 3 0 EGF-like domain EGF_2 PF07974.13 OWF46348.1 - 0.00029 21.2 43.5 0.0022 18.4 14.6 2.9 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.27 OWF46348.1 - 0.00032 20.9 27.0 0.0062 16.8 9.4 2.8 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 OWF46349.1 - 2e-05 24.8 12.2 2e-05 24.8 12.2 3.1 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 OWF46349.1 - 0.35 11.0 20.1 0.055 13.5 6.2 2.7 2 0 0 2 2 2 0 Tenascin EGF domain EGF PF00008.27 OWF46349.1 - 2.9 8.3 24.3 0.57 10.5 8.6 2.9 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 OWF46349.1 - 9 6.5 21.1 0.82 9.9 7.7 2.7 1 1 1 2 2 2 0 Laminin EGF domain DUF1831 PF08866.10 OWF46350.1 - 0.0049 17.3 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 Putative amino acid metabolism EGF_2 PF07974.13 OWF46350.1 - 0.023 15.1 11.7 0.023 15.1 11.7 3.2 2 1 0 2 2 2 0 EGF-like domain ATE_C PF04377.15 OWF46351.1 - 3.8e-41 140.9 0.7 3.8e-41 140.9 0.7 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus Acyl-ACP_TE PF01643.17 OWF46352.1 - 8e-11 41.7 0.1 1e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF46352.1 - 0.015 15.7 1.5 0.087 13.3 0.3 2.5 2 1 0 2 2 2 0 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OWF46353.1 - 1.1e-09 37.9 0.0 2.4e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF46353.1 - 3.3e-05 24.4 0.2 0.00014 22.4 0.1 1.9 2 0 0 2 2 2 1 Thioesterase-like superfamily Gal_Lectin PF02140.18 OWF46354.1 - 5.8e-17 61.9 4.7 5.8e-17 61.9 4.7 3.0 4 0 0 4 4 4 1 Galactose binding lectin domain Lectin_C PF00059.21 OWF46354.1 - 4.5e-05 24.1 4.2 0.063 14.0 0.4 3.2 2 0 0 2 2 2 2 Lectin C-type domain WSC PF01822.19 OWF46354.1 - 0.0011 19.1 8.1 0.0027 17.8 5.9 2.9 2 0 0 2 2 2 1 WSC domain TMEM51 PF15345.6 OWF46354.1 - 0.014 15.2 1.8 0.034 14.0 1.8 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 MFS_1 PF07690.16 OWF46355.1 - 1.3e-19 70.4 36.7 1.6e-14 53.6 7.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_1 PF00515.28 OWF46356.1 - 1.1e-09 37.7 1.1 0.0012 18.5 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF46356.1 - 6.4e-08 32.1 5.0 0.078 13.1 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF46356.1 - 6.4e-07 29.6 2.3 0.0044 17.3 0.2 3.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46356.1 - 9.9e-07 28.4 0.0 0.0021 18.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46356.1 - 0.0018 18.3 2.3 0.66 10.3 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF46356.1 - 0.0078 16.4 1.3 3.3 8.0 0.1 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 OWF46356.1 - 0.0084 15.5 0.0 0.019 14.4 0.0 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 OWF46356.1 - 0.031 14.2 3.1 0.14 12.1 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 OWF46356.1 - 0.073 13.2 0.1 0.93 9.6 0.0 2.4 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region EIF_2_alpha PF07541.12 OWF46356.1 - 0.15 12.1 0.3 0.35 11.0 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit TPR_1 PF00515.28 OWF46357.1 - 6.5e-17 60.6 11.3 0.0016 18.2 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF46357.1 - 1e-15 56.5 10.8 0.032 14.4 0.2 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF46357.1 - 6.9e-08 32.7 12.5 0.0099 16.2 0.2 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OWF46357.1 - 5.5e-06 26.9 0.7 1.8 9.2 0.0 4.7 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46357.1 - 6.7e-06 25.8 4.4 0.0039 17.1 0.0 4.6 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46357.1 - 1.1e-05 25.9 2.1 0.24 12.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46357.1 - 2.6e-05 24.7 8.2 0.0098 16.4 0.1 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF46357.1 - 9.9e-05 22.0 0.4 0.17 11.6 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 OWF46357.1 - 0.00079 19.4 12.5 1.2 9.5 0.1 5.7 6 0 0 6 6 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF46357.1 - 0.0011 19.1 11.2 0.96 9.7 2.9 4.7 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OWF46357.1 - 0.0018 18.6 6.0 0.034 14.5 0.1 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF46357.1 - 0.0024 18.0 0.7 0.029 14.5 0.7 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF46357.1 - 0.0037 16.7 1.4 0.041 13.3 0.1 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 OWF46357.1 - 0.69 9.9 8.4 0.25 11.3 0.6 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF46357.1 - 0.91 10.3 7.8 7 7.5 0.2 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4665 PF15679.5 OWF46357.1 - 5.7 7.6 8.2 0.52 11.0 0.4 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4665) TPR_2 PF07719.17 OWF46358.1 - 1.9e-28 96.2 14.5 2.3e-05 24.1 0.1 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 OWF46358.1 - 1.6e-22 79.6 17.7 1.1e-07 32.1 0.1 6.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46358.1 - 3.3e-22 77.3 15.3 3.6e-05 23.4 0.1 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF46358.1 - 8.6e-13 48.4 3.7 3.8e-12 46.3 0.4 2.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 OWF46358.1 - 1.6e-11 43.5 12.6 0.044 14.0 0.3 8.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46358.1 - 3.1e-11 42.5 16.8 0.13 12.3 0.1 7.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OWF46358.1 - 5.1e-11 43.0 4.4 0.00018 22.0 0.0 6.5 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF46358.1 - 8.9e-11 41.3 5.8 0.00026 20.6 0.0 5.9 6 0 0 6 6 6 2 TPR repeat TPR_14 PF13428.6 OWF46358.1 - 1.2e-09 38.1 4.2 2.3 9.3 0.1 7.0 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46358.1 - 1.5e-08 35.0 2.9 0.21 12.1 0.0 5.6 3 2 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF46358.1 - 2e-07 31.1 7.5 0.077 13.2 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OWF46358.1 - 1.4e-06 28.3 4.5 9.5 6.9 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46358.1 - 8.1e-06 25.5 5.0 4.9 7.2 0.0 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF46358.1 - 9.5e-06 25.9 13.2 16 6.4 0.1 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF46358.1 - 0.0047 17.0 1.0 24 5.2 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF5113 PF17140.4 OWF46358.1 - 0.25 11.2 3.9 41 3.9 0.1 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF5113) SID-1_RNA_chan PF13965.6 OWF46358.1 - 9 4.6 6.4 12 4.2 6.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PPP4R2 PF09184.11 OWF46358.1 - 9.4 5.7 32.9 17 4.9 32.9 1.4 1 0 0 1 1 1 0 PPP4R2 DRE2_N PF16803.5 OWF46359.1 - 0.15 12.3 11.1 27 5.0 0.0 6.6 3 2 4 7 7 7 0 Fe-S cluster assembly protein DRE2 N-terminus DUF2862 PF11061.8 OWF46359.1 - 0.31 10.9 11.4 0.42 10.5 0.3 4.9 2 2 6 8 8 8 0 Protein of unknown function (DUF2862) FeoA PF04023.14 OWF46359.1 - 1.8 8.9 6.1 13 6.2 0.3 4.2 2 1 3 5 5 5 0 FeoA domain Sulf_coat_C PF12193.8 OWF46359.1 - 2.2 8.4 5.2 1.7e+02 2.3 0.0 5.7 8 2 0 8 8 8 0 Sulfolobus virus coat protein C terminal ArnB_C PF18677.1 OWF46360.1 - 8.3e-06 25.8 51.8 1.1 9.4 4.9 7.8 1 1 6 7 7 7 6 Archaellum regulatory network B, C-terminal domain Imm3 PF14425.6 OWF46360.1 - 2.3e-05 24.4 35.5 1.5 8.8 1.1 7.3 1 1 7 8 8 8 6 Immunity protein Imm3 PsbU PF06514.11 OWF46360.1 - 0.00029 20.8 20.0 1.1 9.3 0.3 6.1 1 1 2 6 6 6 3 Photosystem II 12 kDa extrinsic protein (PsbU) RII_binding_1 PF10522.9 OWF46360.1 - 0.0026 17.8 11.5 4.5 7.8 0.2 7.9 9 1 0 9 9 9 1 RII binding domain GPHH PF16905.5 OWF46360.1 - 0.0099 15.6 10.5 1.5e+02 2.3 0.0 9.4 9 2 1 11 11 11 0 Voltage-dependent L-type calcium channel, IQ-associated Plasmodium_HRP PF05403.11 OWF46360.1 - 0.056 13.2 53.7 5.7 6.7 15.9 4.4 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) DUF3819 PF12842.7 OWF46360.1 - 2 8.4 34.5 3.4 7.6 1.8 6.3 1 1 5 6 6 6 0 Domain of unknown function (DUF3819) FRB_dom PF08771.11 OWF46360.1 - 2.7 8.5 23.7 7.5 7.0 2.4 5.1 1 1 4 5 5 5 0 FKBP12-rapamycin binding domain IF-2 PF11987.8 OWF46360.1 - 3 8.0 19.3 15 5.8 0.8 5.4 2 1 2 5 5 5 0 Translation-initiation factor 2 DUF2877 PF11392.8 OWF46360.1 - 9 7.1 20.8 22 5.8 0.4 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF2877) SSF PF00474.17 OWF46361.1 - 3.5e-45 154.6 28.7 5.9e-45 153.8 28.7 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF485 PF04341.12 OWF46361.1 - 2.1 8.3 11.1 3.3 7.7 5.9 3.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 zf-RING_UBOX PF13445.6 OWF46362.1 - 1.8e-09 37.4 7.5 1.8e-09 37.4 7.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF46362.1 - 3.7e-08 33.6 7.9 3.7e-08 33.6 7.9 4.7 5 0 0 5 5 4 1 Ring finger domain zf-RING_5 PF14634.6 OWF46362.1 - 8e-08 32.1 8.0 8e-08 32.1 8.0 4.5 4 1 1 5 5 5 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF46362.1 - 1.1e-07 31.6 8.7 1.1e-07 31.6 8.7 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF46362.1 - 3.6e-06 26.7 8.8 3.6e-06 26.7 8.8 3.6 4 1 0 4 4 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF46362.1 - 4.8e-06 26.6 25.9 5.3e-05 23.3 13.2 5.1 5 0 0 5 5 5 2 B-box zinc finger zf-RING_11 PF17123.5 OWF46362.1 - 0.00027 20.6 3.3 0.00027 20.6 3.3 2.5 2 0 0 2 2 2 1 RING-like zinc finger DUF5082 PF16888.5 OWF46362.1 - 0.00078 19.7 4.5 0.036 14.3 0.3 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF5082) zf-C3HC4_4 PF15227.6 OWF46362.1 - 0.0023 18.1 10.5 0.0023 18.1 10.5 4.2 4 1 0 4 4 3 1 zinc finger of C3HC4-type, RING DHC_N1 PF08385.12 OWF46362.1 - 0.0042 15.8 0.3 0.0042 15.8 0.3 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DUF86 PF01934.17 OWF46362.1 - 0.011 15.5 0.2 6.3 6.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF86 DNTTIP1_dimer PF18192.1 OWF46362.1 - 0.024 15.0 0.3 0.087 13.2 0.0 2.1 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain Linocin_M18 PF04454.12 OWF46362.1 - 0.042 13.1 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 Encapsulating protein for peroxidase NPV_P10 PF05531.12 OWF46362.1 - 0.12 12.8 0.7 0.27 11.7 0.1 1.9 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 OWF46362.1 - 0.52 9.6 5.4 0.096 12.0 1.3 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 OWF46362.1 - 0.54 10.5 3.6 0.34 11.1 0.6 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Stn1_C PF12659.7 OWF46362.1 - 0.63 10.0 4.2 1.4 8.9 0.4 2.5 2 1 0 2 2 2 0 Telomere capping C-terminal wHTH Occludin_ELL PF07303.13 OWF46362.1 - 3 8.6 6.4 1.2 9.9 2.5 2.2 2 0 0 2 2 2 0 Occludin homology domain WD40 PF00400.32 OWF46363.1 - 4.2e-19 68.5 4.3 0.00013 22.7 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 OWF46363.1 - 0.016 15.1 0.2 0.12 12.2 0.1 2.0 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A oligo_HPY PF08352.12 OWF46363.1 - 0.073 13.6 0.0 15 6.2 0.0 3.0 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region ANAPC4_WD40 PF12894.7 OWF46363.1 - 0.081 13.2 0.0 2.2 8.7 0.0 3.1 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain KH_9 PF17904.1 OWF46364.1 - 1.4e-32 111.9 0.9 1.7e-31 108.4 0.5 2.5 2 0 0 2 2 2 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 OWF46364.1 - 9e-25 86.3 1.1 1.7e-24 85.4 0.1 2.1 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 OWF46364.1 - 2.1e-16 59.5 0.3 1.1e-09 37.9 0.0 3.1 3 0 0 3 3 3 2 KH domain FXMRP1_C_core PF12235.8 OWF46364.1 - 6e-16 59.3 4.9 6e-16 59.3 4.9 3.7 1 1 3 4 4 4 2 Fragile X-related 1 protein core C terminal KH_2 PF07650.17 OWF46364.1 - 0.0087 15.9 0.3 6.4 6.7 0.1 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 OWF46364.1 - 0.12 12.2 1.7 8.1 6.4 0.1 3.4 3 1 0 3 3 3 0 KH domain ShK PF01549.24 OWF46365.1 - 3.5e-21 75.4 39.4 4e-09 36.9 7.2 3.2 3 0 0 3 3 3 3 ShK domain-like zf-CCCH PF00642.24 OWF46365.1 - 0.036 14.0 10.0 2.1 8.4 0.2 3.9 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L29 PF00831.23 OWF46366.1 - 3.2 7.8 6.7 0.94 9.5 1.8 2.3 2 1 0 2 2 2 0 Ribosomal L29 protein ShK PF01549.24 OWF46367.1 - 3.4e-16 59.5 28.7 4.3e-08 33.6 11.0 2.4 2 0 0 2 2 2 2 ShK domain-like zf-CCCH PF00642.24 OWF46367.1 - 0.11 12.4 6.7 1.3 9.0 0.1 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ETX_MTX2 PF03318.13 OWF46368.1 - 0.025 14.4 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DDE_Tnp_4 PF13359.6 OWF46369.1 - 2.8e-11 43.3 0.0 4.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 OWF46369.1 - 0.00034 20.9 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 OWF46369.1 - 0.00058 19.6 0.1 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain partial_CstF PF15861.5 OWF46369.1 - 0.014 15.1 0.4 0.03 14.1 0.4 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain SWIM PF04434.17 OWF46369.1 - 0.65 9.7 4.3 0.32 10.7 1.4 2.0 2 0 0 2 2 2 0 SWIM zinc finger VKG_Carbox PF05090.14 OWF46370.1 - 5.1e-123 411.1 17.2 6.7e-123 410.7 17.2 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase ig PF00047.25 OWF46372.1 - 6.3e-15 55.1 0.4 3.3e-09 36.8 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 OWF46372.1 - 6.3e-15 55.5 0.0 2.6e-07 31.1 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 OWF46372.1 - 4.5e-13 49.3 0.0 4e-07 30.3 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain 7tm_2 PF00002.24 OWF46372.1 - 2.6e-12 46.6 25.4 4.2e-12 45.9 25.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) I-set PF07679.16 OWF46372.1 - 2.7e-11 43.4 0.0 6.1e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin I-set domain CUB PF00431.20 OWF46372.1 - 7.1e-08 32.8 0.2 6.7e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 CUB domain V-set PF07686.17 OWF46372.1 - 9.7e-06 25.7 0.0 0.0062 16.7 0.0 3.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain GAIN PF16489.5 OWF46372.1 - 0.002 17.6 0.1 0.0038 16.7 0.1 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain cEGF PF12662.7 OWF46372.1 - 0.0049 16.8 0.5 0.0049 16.8 0.5 3.9 4 0 0 4 4 4 1 Complement Clr-like EGF-like GPS PF01825.21 OWF46372.1 - 0.0086 16.6 2.6 0.0086 16.6 2.6 3.4 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif CAP PF00188.26 OWF46373.1 - 1e-13 52.2 5.3 1.6e-13 51.6 5.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ldl_recept_b PF00058.17 OWF46375.1 - 4.2e-42 142.4 7.4 6.2e-12 45.8 0.1 5.2 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B SGL PF08450.12 OWF46375.1 - 0.00014 21.5 2.0 0.1 12.2 0.2 2.8 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DOMON PF03351.17 OWF46377.1 - 8.9e-18 64.7 0.1 1.5e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 OWF46377.1 - 7e-08 32.7 4.0 7e-08 32.7 4.0 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 EF-hand_1 PF00036.32 OWF46378.1 - 2.8e-17 60.9 16.1 5e-06 25.7 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF46378.1 - 3e-16 57.9 10.8 4.9e-05 22.9 0.0 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OWF46378.1 - 7.3e-16 58.4 11.7 1.3e-10 41.6 3.9 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF46378.1 - 3.5e-13 48.4 14.2 1.6e-06 27.3 1.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OWF46378.1 - 1.4e-12 47.2 9.4 5.4e-08 32.6 0.5 3.6 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF46378.1 - 0.00012 22.4 1.7 0.065 13.6 0.2 3.0 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF46378.1 - 0.0071 17.2 0.6 0.25 12.2 0.2 2.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OWF46378.1 - 0.012 15.5 5.6 0.98 9.4 0.1 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Imm40 PF15569.6 OWF46378.1 - 0.018 15.1 0.2 0.04 14.0 0.1 1.6 1 1 0 1 1 1 0 Immunity protein 40 DUF2213 PF09979.9 OWF46378.1 - 0.019 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) EF-hand_9 PF14658.6 OWF46378.1 - 0.038 14.3 0.6 4.7 7.6 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain Acetyltransf_11 PF13720.6 OWF46378.1 - 0.046 14.2 0.1 16 6.0 0.0 2.5 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_14 PF17959.1 OWF46378.1 - 1.1 9.6 3.8 27 5.2 0.1 3.1 3 1 0 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 OWF46378.1 - 2.7 8.2 5.6 4.3 7.6 0.2 2.7 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_7 PF13499.6 OWF46379.1 - 3.6e-25 88.2 1.5 1.2e-14 54.5 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF46379.1 - 1.2e-24 84.1 2.0 1.2e-05 24.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OWF46379.1 - 1.7e-23 80.3 5.5 5.4e-08 31.8 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OWF46379.1 - 6.3e-20 69.7 3.3 1.3e-05 24.5 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF46379.1 - 2.2e-13 49.9 5.7 1.1e-06 28.3 0.1 3.7 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF46379.1 - 1.2e-07 32.1 0.2 0.0092 16.3 0.0 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF46379.1 - 8.1e-06 25.9 0.8 0.44 10.8 0.5 3.3 2 1 1 3 3 3 3 Dockerin type I domain EF-hand_4 PF12763.7 OWF46379.1 - 0.00057 19.8 0.9 0.21 11.6 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 OWF46379.1 - 0.015 15.2 0.3 5 7.1 0.0 3.2 3 1 0 3 3 3 0 EF hand VCBS PF13517.6 OWF46379.1 - 0.076 13.6 0.9 10 6.8 0.0 2.7 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_9 PF14658.6 OWF46379.1 - 0.12 12.7 0.4 0.91 9.9 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain PMBR PF09373.10 OWF46379.1 - 0.4 10.9 1.3 10 6.4 0.0 3.4 3 0 0 3 3 3 0 Pseudomurein-binding repeat Collagen PF01391.18 OWF46380.1 - 5.7e-31 106.1 110.9 1.6e-09 37.3 33.2 4.4 2 1 3 5 5 5 4 Collagen triple helix repeat (20 copies) AdoMetDC_leader PF08132.11 OWF46381.1 - 0.00014 21.7 9.8 5.8 6.9 0.1 5.5 5 2 1 6 6 6 3 S-adenosyl-l-methionine decarboxylase leader peptide Rio2_N PF09202.11 OWF46381.1 - 1.7 8.9 4.5 5 7.4 0.5 2.8 1 1 2 3 3 3 0 Rio2, N-terminal TRP_2 PF08344.11 OWF46383.1 - 4.2e-05 23.7 15.3 65 3.8 0.0 10.0 1 1 11 12 12 12 0 Transient receptor ion channel II DUF2816 PF10992.8 OWF46383.1 - 0.00019 21.2 8.3 2.7 8.0 0.2 5.0 1 1 4 5 5 5 4 Protein of unknown function (DUF2816) SQAPI PF16845.5 OWF46383.1 - 0.0018 18.6 23.2 15 6.0 0.4 6.7 1 1 8 9 9 9 8 Aspartic acid proteinase inhibitor Gemini_AL1_M PF08283.11 OWF46383.1 - 0.047 13.8 0.6 7.5 6.7 0.1 4.0 1 1 3 4 4 4 0 Geminivirus rep protein central domain DUF5481 PF17578.2 OWF46383.1 - 0.64 10.5 9.0 14 6.1 0.4 4.2 1 1 4 5 5 5 0 Family of unknown function (DUF5481) PDZ PF00595.24 OWF46384.1 - 6.2e-172 558.4 74.5 1.5e-16 60.5 0.3 12.7 13 0 0 13 13 13 12 PDZ domain PDZ_6 PF17820.1 OWF46384.1 - 1.4e-81 268.2 45.4 6.5e-09 35.5 0.1 12.6 12 0 0 12 12 12 12 PDZ domain PDZ_2 PF13180.6 OWF46384.1 - 7.8e-48 160.7 39.1 4.5e-05 23.7 0.3 12.7 12 0 0 12 12 12 12 PDZ domain PDZ_4 PF17816.1 OWF46384.1 - 2.8e-05 24.5 4.5 44 4.5 0.0 8.1 8 0 0 8 8 8 0 PDZ domain PUA PF01472.20 OWF46384.1 - 0.76 9.8 10.4 11 6.1 0.1 6.1 7 0 0 7 7 7 0 PUA domain FYRC PF05965.14 OWF46384.1 - 2.2 8.5 4.9 1.2 9.4 0.0 3.1 4 0 0 4 4 4 0 F/Y rich C-terminus ABC_transp_aux PF09822.9 OWF46385.1 - 4.4e-05 23.1 0.0 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Pkinase PF00069.25 OWF46386.1 - 2.6e-70 236.8 0.0 3.4e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF46386.1 - 3.8e-33 114.9 0.0 5.2e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 OWF46386.1 - 2.9e-20 72.3 0.4 5.9e-20 71.4 0.4 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 OWF46386.1 - 2.9e-07 30.1 0.0 7.9e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OWF46386.1 - 0.00037 21.1 0.9 0.00062 20.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 OWF46386.1 - 0.00057 19.6 0.1 0.06 13.0 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OWF46386.1 - 0.0017 17.8 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF46386.1 - 0.05 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain zf-C2H2_4 PF13894.6 OWF46387.1 - 2.1e-14 52.9 62.1 0.00024 21.7 2.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF46387.1 - 1.6e-13 50.3 65.0 1.3e-05 25.4 5.4 8.3 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF46387.1 - 0.00058 20.2 70.8 0.0007 19.9 2.0 7.8 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF46387.1 - 0.0088 16.0 2.3 0.0088 16.0 2.3 7.3 7 0 0 7 7 7 2 C2H2-type zinc finger SET PF00856.28 OWF46387.1 - 0.022 15.2 0.2 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 SET domain DUF4198 PF10670.9 OWF46387.1 - 0.035 14.5 0.5 0.13 12.6 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) zf-C2H2_2 PF12756.7 OWF46387.1 - 3.1 8.2 34.3 12 6.3 5.5 5.6 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 OWF46387.1 - 5.4 7.4 29.7 0.035 14.4 2.7 4.8 2 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding CHCH PF06747.13 OWF46388.1 - 0.00012 22.1 4.0 0.00019 21.4 4.0 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 OWF46388.1 - 0.017 15.4 1.3 0.033 14.5 1.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF1467 PF07330.12 OWF46392.1 - 1.9e-07 30.9 128.4 10 6.1 0.6 19.0 19 0 0 19 19 19 19 Protein of unknown function (DUF1467) Sushi PF00084.20 OWF46394.1 - 4e-124 405.2 106.2 2e-10 41.1 0.5 19.6 19 0 0 19 19 19 17 Sushi repeat (SCR repeat) Kringle PF00051.18 OWF46394.1 - 2.2e-81 268.2 47.4 9.7e-23 80.3 6.0 5.3 4 0 0 4 4 4 4 Kringle domain EF-hand_1 PF00036.32 OWF46395.1 - 1.4e-26 90.0 17.5 0.00014 21.1 0.1 6.8 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 OWF46395.1 - 4.3e-23 81.5 19.2 6.4e-10 39.4 0.6 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF46395.1 - 7.7e-21 72.2 16.2 0.00079 19.2 0.0 7.2 6 1 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 OWF46395.1 - 1.4e-19 68.6 18.0 0.00061 19.2 0.1 7.0 7 0 0 7 7 7 6 EF hand EF-hand_8 PF13833.6 OWF46395.1 - 6.1e-13 48.4 13.2 0.00026 20.7 0.0 5.6 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF46395.1 - 3.9e-06 27.2 17.8 0.045 14.1 2.9 3.4 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OWF46395.1 - 0.012 15.5 11.9 2.7 7.9 0.2 4.4 4 0 0 4 4 4 0 EF hand Imm74 PF15603.6 OWF46395.1 - 0.25 11.6 3.1 0.42 10.8 0.1 2.6 2 1 0 2 2 2 0 Immunity protein 74 DFRP_C PF16543.5 OWF46395.1 - 1 9.9 10.1 0.52 10.8 6.5 2.4 2 1 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Lipocalin_2 PF08212.12 OWF46396.1 - 0.00042 20.3 0.1 0.00066 19.6 0.1 1.4 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF46396.1 - 0.0011 19.2 0.2 0.0069 16.6 0.0 2.0 2 0 0 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 OWF46397.1 - 1e-10 41.7 0.1 1.4e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF46397.1 - 1.3e-08 35.1 0.7 5.6e-08 33.1 0.7 2.0 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF46397.1 - 7.1e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 1 0 1 1 1 1 Triabin VDE PF07137.11 OWF46397.1 - 0.02 14.5 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 VDE lipocalin domain CTK3_C PF12350.8 OWF46397.1 - 0.027 14.6 0.1 0.062 13.5 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus Vps51 PF08700.11 OWF46398.1 - 4.6e-16 58.7 1.2 3.1e-15 56.0 1.5 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 OWF46398.1 - 0.0032 17.3 0.8 0.0088 15.9 0.8 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps53_N PF04100.12 OWF46398.1 - 0.0072 15.3 7.9 0.07 12.1 7.8 2.6 2 1 0 2 2 2 1 Vps53-like, N-terminal GIT1_C PF12205.8 OWF46398.1 - 2 8.5 8.4 19 5.4 0.1 3.7 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term PPP4R2 PF09184.11 OWF46399.1 - 0.03 13.9 1.5 0.04 13.5 1.5 1.2 1 0 0 1 1 1 0 PPP4R2 PDZ_6 PF17820.1 OWF46400.1 - 0.0026 17.6 0.1 0.0053 16.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 OWF46400.1 - 0.0056 17.0 0.0 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 OWF46400.1 - 0.0057 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF46400.1 - 0.0058 17.0 0.6 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Caskin-Pro-rich PF16907.5 OWF46400.1 - 0.26 11.8 4.8 0.78 10.3 0.5 3.0 2 0 0 2 2 2 0 Proline rich region of Caskin proteins PDZ PF00595.24 OWF46401.1 - 1.8e-25 89.1 1.1 1.7e-14 53.9 0.1 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OWF46401.1 - 4.3e-12 45.7 0.0 1.8e-06 27.7 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OWF46401.1 - 0.0083 16.4 0.1 5.2 7.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain YARHG PF13308.6 OWF46401.1 - 0.062 13.2 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 YARHG domain PAS_11 PF14598.6 OWF46403.1 - 4.7e-27 94.3 0.6 4.7e-27 94.3 0.6 4.6 4 0 0 4 4 4 1 PAS domain PAS_3 PF08447.12 OWF46403.1 - 4.6e-09 36.4 0.0 1.1e-05 25.6 0.0 2.7 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 OWF46403.1 - 0.00028 20.8 1.1 0.00028 20.8 1.1 2.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 OWF46403.1 - 0.0006 19.8 0.0 0.0006 19.8 0.0 4.8 5 0 0 5 5 5 1 PAS fold PAS_9 PF13426.7 OWF46403.1 - 0.0014 18.9 0.0 0.016 15.4 0.0 2.8 2 0 0 2 2 2 1 PAS domain RVT_3 PF13456.6 OWF46405.1 - 0.00025 20.8 4.3 0.46 10.3 0.3 2.9 1 1 2 3 3 3 3 Reverse transcriptase-like BRICHOS PF04089.14 OWF46405.1 - 0.002 18.3 7.3 0.56 10.5 0.1 3.6 1 1 3 4 4 4 3 BRICHOS domain ISP3_C PF18045.1 OWF46405.1 - 0.012 15.5 1.2 0.11 12.4 1.0 2.3 1 1 0 1 1 1 0 ISP3 C-terminal FOLN PF09289.10 OWF46405.1 - 0.016 15.4 14.4 58 4.0 0.2 6.0 6 0 0 6 6 6 0 Follistatin/Osteonectin-like EGF domain Colipase-like PF15083.6 OWF46405.1 - 0.019 15.1 1.6 0.026 14.6 1.6 1.2 1 0 0 1 1 1 0 Colipase-like PBSX_XtrA PF17356.2 OWF46405.1 - 0.036 14.0 5.5 1.4 8.9 1.2 2.9 1 1 1 2 2 2 0 Phage-like element PBSX protein XtrA Haem_degrading PF03928.14 OWF46405.1 - 0.1 12.7 0.4 0.39 10.8 0.4 1.8 1 1 0 1 1 1 0 Haem-degrading Colipase PF01114.18 OWF46405.1 - 0.11 12.2 4.3 17 5.2 0.4 3.4 1 1 2 3 3 3 0 Colipase, N-terminal domain Flg_hook PF02120.16 OWF46405.1 - 0.19 11.7 0.1 42 4.1 0.0 2.6 1 1 2 3 3 3 0 Flagellar hook-length control protein FliK Beta_helix PF13229.6 OWF46406.1 - 7e-51 172.2 57.4 1.2e-19 70.7 7.7 5.3 3 2 2 5 5 5 4 Right handed beta helix region NosD PF05048.13 OWF46406.1 - 1e-34 119.9 33.1 1.6e-12 47.2 1.5 4.7 2 1 2 5 5 5 4 Periplasmic copper-binding protein (NosD) F-box PF00646.33 OWF46406.1 - 6.1e-10 38.7 2.9 1.4e-09 37.5 2.9 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OWF46406.1 - 3.1e-08 33.4 3.0 6.2e-08 32.4 3.0 1.5 1 0 0 1 1 1 1 F-box-like DUF3715 PF12509.8 OWF46406.1 - 0.65 10.0 6.5 0.35 10.8 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3715) PDZ PF00595.24 OWF46407.1 - 2.7e-17 62.9 0.1 4.4e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF46407.1 - 4e-11 42.6 0.2 1.2e-10 41.0 0.1 2.0 2 1 0 2 2 2 1 PDZ domain PH_17 PF18012.1 OWF46407.1 - 1.2e-07 31.4 0.0 3.3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PDZ_2 PF13180.6 OWF46407.1 - 0.00011 22.4 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 OWF46407.1 - 0.00092 19.7 0.0 0.014 15.9 0.0 2.4 2 0 0 2 2 2 1 PH domain Tricorn_PDZ PF14685.6 OWF46407.1 - 0.038 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF1126 PF06565.12 OWF46408.1 - 4.8e-103 338.1 1.3 1.3e-34 118.1 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 OWF46408.1 - 0.00042 19.7 0.1 0.0013 18.1 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OWF46408.1 - 0.0025 17.6 0.0 0.013 15.4 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OWF46408.1 - 0.0054 17.2 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair ACOX PF01756.19 OWF46410.1 - 5.6e-58 195.5 2.2 9.7e-58 194.7 0.6 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OWF46410.1 - 1e-30 106.9 1.1 2.4e-30 105.7 0.2 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OWF46410.1 - 9.1e-08 32.2 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OWF46410.1 - 0.0058 17.3 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain ECR1_N PF14382.6 OWF46410.1 - 0.08 12.8 1.2 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Acyl-CoA_dh_1 PF00441.24 OWF46410.1 - 0.084 13.1 2.8 0.39 10.9 0.1 2.8 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain TetR_C_7 PF14246.6 OWF46410.1 - 0.11 12.5 0.9 0.27 11.3 0.9 1.6 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain Filament PF00038.21 OWF46411.1 - 1.4e-05 24.9 52.3 1.4e-05 24.9 52.3 5.8 1 1 4 5 5 5 1 Intermediate filament protein DUF3584 PF12128.8 OWF46411.1 - 2.7e-05 21.9 62.8 2.7e-05 21.9 62.8 3.6 1 1 0 2 2 2 1 Protein of unknown function (DUF3584) GAS PF13851.6 OWF46411.1 - 6.2e-05 22.4 140.7 0.00034 20.0 11.6 8.0 2 2 5 7 7 7 5 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 OWF46411.1 - 0.00067 18.4 77.2 0.0019 16.9 38.2 4.0 1 1 3 4 4 4 2 AAA domain Spc7 PF08317.11 OWF46411.1 - 0.0015 17.5 24.3 0.0015 17.5 24.3 6.4 1 1 5 6 6 6 4 Spc7 kinetochore protein ERM PF00769.19 OWF46411.1 - 0.0032 17.3 139.5 0.027 14.3 28.2 6.1 1 1 5 6 6 6 3 Ezrin/radixin/moesin family FUSC PF04632.12 OWF46411.1 - 0.0043 15.7 16.3 0.015 13.9 3.2 2.8 1 1 1 2 2 2 2 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 OWF46411.1 - 0.0055 16.8 24.0 0.0055 16.8 24.0 8.0 2 1 6 8 8 8 5 TPR/MLP1/MLP2-like protein TLD PF07534.16 OWF46413.1 - 9.1e-16 58.3 0.1 1e-15 58.2 0.1 1.1 1 0 0 1 1 1 1 TLD GTP_EFTU PF00009.27 OWF46414.1 - 3.7e-06 26.6 0.1 0.0018 17.8 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF46414.1 - 8.8e-06 25.7 0.1 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 OWF46414.1 - 0.00014 21.3 0.0 0.0023 17.4 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF46414.1 - 0.00024 21.1 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OWF46414.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 OWF46414.1 - 0.0022 17.4 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Septin cobW PF02492.19 OWF46414.1 - 0.0032 17.1 0.2 0.67 9.5 0.1 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OWF46414.1 - 0.0036 17.1 0.2 2.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein MCM PF00493.23 OWF46414.1 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Gtr1_RagA PF04670.12 OWF46414.1 - 0.013 14.9 0.8 0.83 9.0 0.8 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AIG1 PF04548.16 OWF46414.1 - 0.056 12.8 0.3 0.38 10.0 0.1 2.1 2 1 1 3 3 3 0 AIG1 family G-alpha PF00503.20 OWF46414.1 - 0.067 12.3 0.0 0.073 12.2 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 OWF46414.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 OWF46414.1 - 0.16 12.0 0.3 0.39 10.7 0.3 1.6 1 0 0 1 1 1 0 Dynamin family Pacs-1 PF10254.9 OWF46415.1 - 4.8e-161 536.4 2.5 4.8e-161 536.4 2.5 1.5 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein XAP5 PF04921.14 OWF46416.1 - 4.2e-88 295.4 9.2 4.2e-88 295.4 9.2 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator SURF2 PF05477.11 OWF46416.1 - 8.8 5.9 26.7 1.4 8.5 19.7 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) F420_oxidored PF03807.17 OWF46417.1 - 1.6e-13 51.0 0.0 3.4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OWF46417.1 - 7.4e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 OWF46417.1 - 0.0086 16.3 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 OWF46417.1 - 0.028 14.0 0.0 0.18 11.4 0.0 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 OWF46417.1 - 0.031 13.6 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 OWF46417.1 - 0.13 12.2 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Rossmann-like domain Forkhead PF00250.18 OWF46418.1 - 5.4e-37 125.9 0.1 9.2e-37 125.2 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain Forkhead_N PF08430.12 OWF46418.1 - 2.6e-14 54.0 49.4 2.6e-14 54.0 49.4 3.0 3 1 0 3 3 3 1 Forkhead N-terminal region HNF_C PF09354.10 OWF46418.1 - 2.4e-08 34.9 0.9 2.4e-08 34.9 0.9 4.3 3 1 0 3 3 3 1 HNF3 C-terminal domain Myc-LZ PF02344.15 OWF46419.1 - 0.23 11.6 3.6 0.39 10.8 3.6 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain VGPC1_C PF16799.5 OWF46421.1 - 0.1 12.6 6.0 0.12 12.4 1.2 3.1 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HTH_32 PF13565.6 OWF46422.1 - 0.057 14.0 0.4 0.14 12.8 0.4 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Josephin PF02099.17 OWF46423.1 - 9.2e-51 172.2 0.1 2.6e-50 170.7 0.0 1.7 2 0 0 2 2 2 1 Josephin UIM PF02809.20 OWF46423.1 - 5.4e-05 22.8 4.7 0.018 14.9 0.7 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif DDE_Tnp_1_6 PF13751.6 OWF46424.1 - 0.01 16.0 1.9 0.01 16.0 1.9 3.1 3 0 0 3 3 3 0 Transposase DDE domain zf-met PF12874.7 OWF46424.1 - 0.041 14.3 0.1 0.25 11.8 0.1 2.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PQQ_3 PF13570.6 OWF46424.1 - 0.19 12.3 0.0 0.65 10.6 0.0 2.0 1 0 0 1 1 1 0 PQQ-like domain zf-C2H2_jaz PF12171.8 OWF46424.1 - 0.66 10.3 6.8 2.5 8.5 0.3 3.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OWF46424.1 - 1 10.0 8.3 27 5.5 5.0 3.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Spy1 PF11357.8 OWF46425.1 - 2.2e-56 189.7 5.5 6.1e-56 188.3 4.9 1.9 2 0 0 2 2 2 1 Cell cycle regulatory protein WD40 PF00400.32 OWF46426.1 - 8.9e-70 228.9 86.8 0.00029 21.6 0.0 28.5 29 0 0 29 29 27 16 WD domain, G-beta repeat HELP PF03451.14 OWF46426.1 - 4e-53 177.2 0.6 4.1e-19 68.2 0.1 3.4 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 OWF46426.1 - 7.8e-34 115.8 12.8 1.2e-06 28.7 0.0 12.7 8 4 5 14 14 14 6 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OWF46426.1 - 1.1e-09 37.3 8.2 0.18 10.3 0.0 7.2 6 2 2 8 8 8 5 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OWF46426.1 - 1.6e-09 37.2 0.6 0.29 10.0 0.0 6.2 6 1 0 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF46426.1 - 1.3e-08 35.0 6.3 0.17 11.7 0.0 8.3 8 3 1 9 9 9 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 OWF46426.1 - 1.3e-08 34.0 0.1 0.037 12.8 0.0 4.7 4 0 0 4 4 4 3 Nup133 N terminal like WD40_like PF17005.5 OWF46426.1 - 6.2e-06 25.7 4.9 0.063 12.6 0.0 6.2 6 1 0 6 6 6 2 WD40-like domain PSII_BNR PF14870.6 OWF46426.1 - 6.9e-06 25.5 0.1 1.2 8.3 0.0 4.3 3 0 0 3 3 3 3 Photosynthesis system II assembly factor YCF48 BBS2_Mid PF14783.6 OWF46426.1 - 0.0015 18.5 0.5 17 5.5 0.0 6.5 7 1 0 7 7 7 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 OWF46426.1 - 0.0031 16.2 0.0 1.2 7.6 0.0 3.7 4 0 0 4 4 4 1 Nucleoporin Nup120/160 PI3K_C2 PF00792.24 OWF46426.1 - 0.11 12.4 1.3 6.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 DUF5582 PF17819.1 OWF46427.1 - 6.4e-16 59.1 0.0 6.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 OWF46427.1 - 0.072 12.2 0.7 0.091 11.8 0.2 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5586) ATP-synt_D PF01813.17 OWF46428.1 - 3.1e-79 265.4 6.9 4e-79 265.0 6.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SHOCT PF09851.9 OWF46428.1 - 0.00035 20.2 2.1 0.0019 17.9 2.1 2.4 1 0 0 1 1 1 1 Short C-terminal domain Vps54_N PF10475.9 OWF46428.1 - 0.02 14.2 0.9 0.037 13.3 0.1 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex SNAP-25 PF00835.19 OWF46429.1 - 5.5e-17 61.8 0.3 5.5e-17 61.8 0.3 1.8 2 0 0 2 2 2 1 SNAP-25 family MscS_porin PF12795.7 OWF46429.1 - 0.00088 18.9 0.2 0.00088 18.9 0.2 2.7 3 0 0 3 3 3 1 Mechanosensitive ion channel porin domain V-SNARE_C PF12352.8 OWF46429.1 - 0.0033 17.7 4.4 0.013 15.8 0.7 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 OWF46429.1 - 0.0075 16.2 6.8 0.019 14.9 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) Polysacc_deac_2 PF04748.13 OWF46429.1 - 0.014 14.6 2.3 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Sec20 PF03908.13 OWF46429.1 - 0.044 13.7 1.0 0.044 13.7 1.0 1.9 2 0 0 2 2 2 0 Sec20 SOAR PF16533.5 OWF46429.1 - 0.057 13.4 4.7 5.1 7.1 0.0 3.1 3 0 0 3 3 3 0 STIM1 Orai1-activating region DUF948 PF06103.11 OWF46429.1 - 0.65 10.3 6.4 16 5.9 1.4 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 OWF46429.1 - 0.98 8.9 5.3 3.8 7.0 5.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 OWF46429.1 - 1.8 9.0 8.6 0.26 11.7 1.2 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Snapin_Pallidin PF14712.6 OWF46429.1 - 9 6.8 10.5 8.8 6.8 3.8 2.2 2 0 0 2 2 2 0 Snapin/Pallidin ACBP PF00887.19 OWF46430.1 - 3.9e-16 59.0 0.0 3.9e-16 59.0 0.0 2.3 2 1 0 2 2 2 1 Acyl CoA binding protein tRNA-synt_1c PF00749.21 OWF46430.1 - 0.32 9.8 9.0 0.49 9.2 9.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain TFIIA PF03153.13 OWF46430.1 - 2.6 7.9 26.7 4.3 7.2 26.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tctex-1 PF03645.13 OWF46431.1 - 1.3e-19 70.3 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family HlyD_D4 PF16572.5 OWF46431.1 - 0.11 12.4 0.1 0.35 10.8 0.1 1.9 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB HHV-5_US34A PF17087.5 OWF46432.1 - 7 6.9 13.0 11 6.2 0.4 3.0 1 1 2 3 3 3 0 Herpesvirus US34A protein family AAA_lid_4 PF17864.1 OWF46432.1 - 7.5 6.4 8.8 35 4.2 5.6 2.6 1 1 1 2 2 2 0 RuvB AAA lid domain Aminotran_1_2 PF00155.21 OWF46433.1 - 7e-56 190.0 0.0 8.3e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OWF46433.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 OWF46433.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Reticulon PF02453.17 OWF46434.1 - 6.8e-44 149.6 7.6 8.4e-44 149.3 7.6 1.1 1 0 0 1 1 1 1 Reticulon EI24 PF07264.11 OWF46434.1 - 3.8 7.7 10.0 0.51 10.5 0.5 2.1 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) AAA_6 PF12774.7 OWF46435.1 - 2.5e-155 516.4 0.2 1e-150 501.2 0.0 2.8 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF46435.1 - 4e-131 437.8 7.3 4e-131 437.8 7.3 3.2 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OWF46435.1 - 2e-94 315.7 0.1 7e-94 314.0 0.1 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OWF46435.1 - 3.3e-94 315.6 0.0 3.3e-94 315.6 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OWF46435.1 - 2.1e-80 269.0 1.3 8.4e-80 267.0 1.3 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF46435.1 - 1.7e-63 213.4 0.1 1.1e-44 152.1 0.0 5.8 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF46435.1 - 2.6e-53 180.2 0.0 7.7e-53 178.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF46435.1 - 5.8e-52 176.8 7.8 9.3e-52 176.2 7.8 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF46435.1 - 3.5e-40 136.8 0.0 8.8e-39 132.3 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OWF46435.1 - 1.8e-17 63.6 0.0 0.0085 16.1 0.0 7.4 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OWF46435.1 - 3.9e-14 52.7 0.7 1.8e-13 50.6 0.7 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 OWF46435.1 - 2e-13 50.5 0.0 3.5e-07 30.3 0.0 3.5 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 OWF46435.1 - 6.1e-12 46.2 11.8 1e-07 32.5 0.0 5.6 5 0 0 5 5 4 1 AAA ATPase domain AAA PF00004.29 OWF46435.1 - 4.3e-09 36.9 1.4 0.074 13.5 0.0 5.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OWF46435.1 - 1.2e-06 28.8 1.0 1 9.8 0.0 4.5 5 0 0 5 5 3 2 RNA helicase RsgA_GTPase PF03193.16 OWF46435.1 - 2.2e-06 27.7 0.4 0.0079 16.1 0.1 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 OWF46435.1 - 2.5e-06 27.8 11.2 0.072 13.4 0.0 6.3 6 0 0 6 6 6 1 AAA domain AAA_18 PF13238.6 OWF46435.1 - 1.9e-05 25.2 1.8 6.5 7.3 0.0 5.6 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 OWF46435.1 - 5.9e-05 23.6 4.4 0.33 11.5 0.2 4.8 4 0 0 4 4 3 1 ABC transporter Rad17 PF03215.15 OWF46435.1 - 6.8e-05 22.9 0.6 1.4 8.8 0.0 4.8 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_29 PF13555.6 OWF46435.1 - 0.00028 20.6 0.2 1.1 9.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain UPF0242 PF06785.11 OWF46435.1 - 0.00084 19.5 2.9 0.00084 19.5 2.9 4.2 5 0 0 5 5 2 1 Uncharacterised protein family (UPF0242) N-terminus ATPase_2 PF01637.18 OWF46435.1 - 0.00096 19.1 0.0 0.0041 17.1 0.0 2.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OWF46435.1 - 0.0014 18.3 2.3 5.8 6.6 0.1 4.4 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 OWF46435.1 - 0.0016 17.5 1.0 0.15 11.1 0.0 3.2 4 0 0 4 4 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 OWF46435.1 - 0.0034 17.5 2.7 71 3.5 0.0 5.8 6 0 0 6 6 5 0 AAA domain Sigma54_activat PF00158.26 OWF46435.1 - 0.0035 17.1 1.7 1.1 9.0 0.0 3.6 4 0 0 4 4 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 OWF46435.1 - 0.0058 16.0 1.6 2.4 7.5 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OWF46435.1 - 0.0077 16.2 1.7 22 5.1 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OWF46435.1 - 0.014 14.6 2.5 1.6 7.8 0.1 3.7 5 0 0 5 5 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OWF46435.1 - 0.028 14.1 0.5 12 5.6 0.1 3.8 3 0 0 3 3 3 0 AAA domain Sec8_exocyst PF04048.14 OWF46435.1 - 0.036 13.9 2.8 0.18 11.7 0.4 3.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain AAA_19 PF13245.6 OWF46435.1 - 0.039 14.3 8.1 8.5 6.7 0.0 5.4 5 0 0 5 5 5 0 AAA domain Rad60-SLD PF11976.8 OWF46435.1 - 0.076 12.9 0.3 0.6 10.0 0.0 2.8 2 0 0 2 2 1 0 Ubiquitin-2 like Rad60 SUMO-like Zeta_toxin PF06414.12 OWF46435.1 - 0.12 11.7 1.0 21 4.3 0.0 3.8 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 OWF46435.1 - 0.12 12.4 0.6 3.3 7.8 0.2 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 OWF46435.1 - 0.25 10.3 1.5 10 5.0 0.1 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 OWF46435.1 - 0.7 9.5 6.8 16 5.1 0.1 3.8 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Histone PF00125.24 OWF46435.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.8 3 0 0 3 3 1 0 Core histone H2A/H2B/H3/H4 DUF745 PF05335.13 OWF46435.1 - 1.4 8.6 13.6 4.9 6.8 2.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) RuvB_N PF05496.12 OWF46435.1 - 1.4 8.6 4.1 34 4.1 0.0 3.5 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain FUSC PF04632.12 OWF46435.1 - 3.3 6.1 5.3 1.4 7.3 0.3 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family NACHT PF05729.12 OWF46435.1 - 3.9 7.3 9.1 1.2 9.0 0.0 4.3 4 0 0 4 4 4 0 NACHT domain RGS PF00615.19 OWF46436.1 - 2.4e-25 89.1 10.5 5.9e-09 36.2 0.2 4.7 4 0 0 4 4 4 4 Regulator of G protein signaling domain PUD1_2 PF18457.1 OWF46436.1 - 0.09 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 CHB_HEX_C_1 PF13290.6 OWF46437.1 - 1.1e-11 44.5 0.2 2.8e-11 43.2 0.2 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 OWF46437.1 - 1.4e-09 37.9 0.0 3.2e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Fn3 associated Ank_2 PF12796.7 OWF46437.1 - 8.3e-08 32.7 0.0 2.5e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF46437.1 - 3.8e-07 30.2 0.1 0.0065 16.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF46437.1 - 3.8e-06 27.3 0.1 0.16 12.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF46437.1 - 0.0004 20.7 0.4 0.19 12.2 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OWF46437.1 - 0.00099 19.4 0.2 1.8 9.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat DZR PF12773.7 OWF46437.1 - 0.081 13.0 0.7 0.17 12.0 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon NUSAP PF16006.5 OWF46438.1 - 8.8e-32 111.0 30.9 8.8e-32 111.0 30.9 4.9 1 1 1 3 3 3 1 Nucleolar and spindle-associated protein Glutaredoxin2_C PF04399.13 OWF46438.1 - 0.0062 16.4 1.0 0.015 15.2 1.0 1.6 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain IML1 PF12257.8 OWF46438.1 - 0.031 13.4 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 EMP24_GP25L PF01105.24 OWF46440.1 - 1.9e-50 171.3 0.0 2.2e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bac_rhamnosid PF05592.11 OWF46441.1 - 0.00025 21.0 5.2 2.8 8.0 0.1 4.4 1 1 5 6 6 6 4 Bacterial alpha-L-rhamnosidase concanavalin-like domain DUF3168 PF11367.8 OWF46441.1 - 0.074 13.2 2.6 6 7.1 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3168) DUF4878 PF12870.7 OWF46441.1 - 0.17 12.2 0.0 77 3.6 0.0 3.7 1 1 5 6 6 6 0 Domain of unknown function (DUF4878) DpnD-PcfM PF14207.6 OWF46441.1 - 0.69 9.8 12.7 1.6e+02 2.3 0.0 8.3 12 0 0 12 12 12 0 DpnD/PcfM-like protein 7tm_1 PF00001.21 OWF46442.1 - 2.7e-29 102.3 5.4 2.7e-29 102.3 5.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF46442.1 - 1.5e-06 28.1 2.9 1.5e-06 28.1 2.9 2.6 3 1 0 3 3 3 2 Olfactory receptor RasGAP PF00616.19 OWF46442.1 - 0.045 13.4 0.4 0.07 12.8 0.4 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase 7tm_1 PF00001.21 OWF46443.1 - 2.6e-30 105.6 7.4 3.2e-30 105.3 7.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 OWF46443.1 - 0.0025 17.6 2.6 0.0025 17.6 2.6 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Stevor PF17410.2 OWF46443.1 - 0.014 15.0 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cytomega_TRL10 PF06084.11 OWF46443.1 - 0.044 13.8 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF2062 PF09835.9 OWF46443.1 - 0.067 13.1 1.3 0.11 12.3 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2207 PF09972.9 OWF46443.1 - 0.52 9.0 7.4 1.7 7.3 0.4 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Comm PF15957.5 OWF46443.1 - 6.5 7.1 5.8 27 5.1 0.0 3.0 2 1 0 2 2 2 0 Commissureless S1FA PF04689.13 OWF46443.1 - 7.2 6.8 11.3 0.11 12.7 1.3 2.9 3 0 0 3 3 3 0 DNA binding protein S1FA FCP1_C PF09309.10 OWF46444.1 - 6.9 6.5 7.1 45 3.8 3.3 2.9 1 1 1 2 2 2 0 FCP1, C-terminal OATP PF03137.20 OWF46445.1 - 1.4e-155 518.7 12.4 8.3e-155 516.2 10.3 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF46445.1 - 9.1e-18 64.3 28.5 3.6e-08 32.7 8.0 3.5 3 1 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF46445.1 - 1e-07 31.9 8.4 1e-07 31.9 8.4 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF46445.1 - 0.02 14.9 9.3 0.071 13.1 9.3 2.0 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Ribosomal_L12_N PF16320.5 OWF46445.1 - 0.11 12.3 0.0 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain Oxidored_q4 PF00507.19 OWF46445.1 - 0.21 11.8 3.1 13 6.0 0.1 3.5 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 OATP PF03137.20 OWF46446.1 - 4.4e-129 431.2 10.3 4.4e-129 431.2 10.2 1.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF46446.1 - 3.5e-16 59.1 20.6 3.5e-16 59.1 20.6 2.3 2 2 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF46446.1 - 2.2e-05 24.5 13.2 4.9e-05 23.4 13.2 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF46446.1 - 0.048 13.7 8.5 0.11 12.6 8.5 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF2371 PF10177.9 OWF46446.1 - 0.18 12.0 1.3 40 4.4 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2371) MFS_1_like PF12832.7 OWF46446.1 - 0.83 8.4 17.2 0.04 12.8 1.7 2.9 3 0 0 3 3 3 0 MFS_1 like family HSD3 PF15244.6 OWF46449.1 - 3.3e-39 135.6 26.7 4.4e-23 82.5 18.2 4.6 2 2 0 3 3 3 2 Spermatogenesis-associated protein 7, or HSD3 ProRS-C_1 PF09180.11 OWF46451.1 - 3.5e-23 81.6 0.9 1e-22 80.1 0.9 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 OWF46451.1 - 2e-14 53.5 0.0 6.3e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OWF46451.1 - 2.3e-14 53.8 0.1 5.8e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 OWF46451.1 - 4.1e-06 26.9 4.5 0.0023 18.1 3.1 3.0 2 0 0 2 2 2 2 WHEP-TRS domain Spc29 PF17082.5 OWF46451.1 - 5.4 6.8 8.4 0.27 11.0 1.0 2.4 3 0 0 3 3 3 0 Spindle Pole Component 29 DNA_pol_E_B PF04042.16 OWF46452.1 - 6.9e-44 149.7 0.0 1.1e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OWF46452.1 - 3.8e-38 130.5 0.8 5.9e-38 129.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain NUDE_C PF04880.13 OWF46453.1 - 2.9e-37 128.8 0.3 2.9e-37 128.8 0.3 2.5 2 0 0 2 2 1 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 OWF46453.1 - 0.016 15.3 32.4 0.24 11.5 14.0 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Pol_alpha_B_N PF08418.10 OWF46453.1 - 0.019 14.9 2.5 0.019 14.9 2.5 2.3 1 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Fez1 PF06818.15 OWF46453.1 - 0.037 14.5 25.1 0.3 11.5 8.4 2.3 1 1 1 2 2 2 0 Fez1 DUF3584 PF12128.8 OWF46453.1 - 0.093 10.2 22.2 0.16 9.4 22.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4795 PF16043.5 OWF46453.1 - 0.12 12.0 16.6 0.21 11.2 16.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3450 PF11932.8 OWF46453.1 - 0.13 11.5 22.9 0.077 12.3 17.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) CCDC144C PF14915.6 OWF46453.1 - 0.16 11.0 26.5 0.37 9.9 26.5 1.6 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region ADIP PF11559.8 OWF46453.1 - 0.18 11.9 25.8 0.8 9.8 18.6 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 OWF46453.1 - 0.22 11.5 33.0 0.18 11.8 15.8 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 OWF46453.1 - 0.27 11.9 21.6 0.39 11.4 9.4 3.1 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 OWF46453.1 - 0.31 12.0 27.1 0.045 14.7 8.9 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 OWF46453.1 - 0.5 10.4 33.0 1.8 8.6 19.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 OWF46453.1 - 0.64 10.2 33.1 0.13 12.5 13.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Serine_rich PF08824.10 OWF46453.1 - 0.66 10.0 9.6 2.1 8.3 3.4 2.8 1 1 1 2 2 2 0 Serine rich protein interaction domain TSC22 PF01166.18 OWF46453.1 - 0.7 10.2 16.7 0.39 11.1 4.6 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family Lectin_N PF03954.14 OWF46453.1 - 0.88 9.3 10.5 0.7 9.6 8.3 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain LMBR1 PF04791.16 OWF46453.1 - 0.94 8.3 13.7 1.3 7.9 13.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 OWF46453.1 - 1.1 8.0 28.6 0.41 9.5 19.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CASP_C PF08172.12 OWF46453.1 - 1.3 8.3 21.5 0.31 10.4 13.6 2.8 1 1 0 2 2 2 0 CASP C terminal DHR10 PF18595.1 OWF46453.1 - 1.6 8.8 34.1 0.44 10.6 13.5 3.4 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain ERM PF00769.19 OWF46453.1 - 1.7 8.4 27.5 0.64 9.8 9.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Atg14 PF10186.9 OWF46453.1 - 1.8 7.6 21.3 6.7 5.7 21.3 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 OWF46453.1 - 1.8 9.0 34.8 2 8.9 5.0 3.7 1 1 3 4 4 4 0 Cell division protein ZapB APG6_N PF17675.1 OWF46453.1 - 1.9 9.0 38.8 4.5 7.8 27.3 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region Tektin PF03148.14 OWF46453.1 - 2 7.1 25.5 5.7 5.6 9.0 2.7 1 1 1 2 2 2 0 Tektin family WXG100 PF06013.12 OWF46453.1 - 2.7 8.3 7.1 12 6.2 2.5 3.4 2 1 0 3 3 3 0 Proteins of 100 residues with WXG TBCC_N PF16752.5 OWF46453.1 - 3.1 8.3 21.3 1.7 9.1 12.5 2.9 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain STAT_alpha PF01017.20 OWF46453.1 - 3.4 7.5 16.7 4.1 7.3 15.4 1.8 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF4407 PF14362.6 OWF46453.1 - 3.4 6.9 14.2 7.3 5.9 14.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 OWF46453.1 - 3.9 7.7 22.5 2.6 8.2 8.5 3.8 2 1 0 3 3 3 0 bZIP transcription factor DUF1664 PF07889.12 OWF46453.1 - 4.5 7.3 13.8 2.9 8.0 7.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DinB PF05163.12 OWF46453.1 - 5.3 6.9 14.1 0.34 10.8 4.5 2.6 1 1 2 3 3 3 0 DinB family GAS PF13851.6 OWF46453.1 - 5.4 6.3 29.1 3 7.1 21.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SpecificRecomb PF10136.9 OWF46453.1 - 6 5.1 6.6 8.1 4.6 6.6 1.1 1 0 0 1 1 1 0 Site-specific recombinase IFT57 PF10498.9 OWF46453.1 - 6.6 5.6 21.3 0.93 8.4 14.8 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF5082 PF16888.5 OWF46453.1 - 7 6.9 16.5 13 6.1 5.2 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF5082) Sigma54_AID PF00309.20 OWF46453.1 - 8.4 6.3 13.3 1.3 8.9 0.5 3.5 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) IQ PF00612.27 OWF46454.1 - 1.7e-06 27.3 0.0 3.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.13 OWF46454.1 - 0.00043 19.9 0.3 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Dpy-30 motif Guanylate_cyc PF00211.20 OWF46455.1 - 4.7e-67 225.2 0.2 8.6e-67 224.3 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 OWF46455.1 - 2.5e-43 148.5 0.0 3.9e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 OWF46455.1 - 4.3e-41 140.9 0.0 7.4e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF46455.1 - 2.6e-31 108.9 0.0 4.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF46455.1 - 0.00021 20.8 1.3 0.00036 20.0 1.3 1.3 1 0 0 1 1 1 1 Heme NO binding associated Peptidase_M13_N PF05649.13 OWF46456.1 - 3.4e-25 89.5 0.2 5.3e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF46456.1 - 4.9e-23 81.8 0.0 9.3e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Neur_chan_LBD PF02931.23 OWF46457.1 - 2.3e-37 128.6 0.0 3e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Guanylate_cyc PF00211.20 OWF46458.1 - 2.1e-63 213.3 0.0 3.6e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 OWF46458.1 - 4.6e-41 141.1 0.0 7.2e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 OWF46458.1 - 5.1e-41 140.7 0.0 7.7e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF46458.1 - 1.1e-28 100.4 0.0 2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF46458.1 - 0.00012 21.6 0.9 0.00023 20.7 0.9 1.4 1 0 0 1 1 1 1 Heme NO binding associated EphA2_TM PF14575.6 OWF46459.1 - 0.044 14.7 0.1 0.13 13.2 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Guanylate_cyc PF00211.20 OWF46460.1 - 1e-62 211.0 0.0 2.1e-62 210.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 OWF46460.1 - 1.1e-38 133.2 0.1 1.7e-38 132.7 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 OWF46460.1 - 5.3e-35 120.9 0.0 9.2e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF46460.1 - 1e-29 103.7 0.0 1.9e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF46460.1 - 0.0033 16.9 0.5 0.0082 15.6 0.5 1.6 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 OWF46460.1 - 0.0057 16.4 0.0 2.1 7.9 0.1 2.2 2 0 0 2 2 2 2 Periplasmic binding protein ox_reductase_C PF08635.10 OWF46461.1 - 5.8e-42 142.7 0.0 8.9e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OWF46461.1 - 5.9e-20 72.3 0.0 9.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OWF46461.1 - 0.0088 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ox_reductase_C PF08635.10 OWF46462.1 - 3.1e-38 130.6 0.0 4.6e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OWF46462.1 - 3.1e-19 70.0 0.0 4.8e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OWF46462.1 - 0.0096 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Aminotran_MocR PF12897.7 OWF46462.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase ox_reductase_C PF08635.10 OWF46463.1 - 8.3e-40 135.7 0.0 1.2e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OWF46463.1 - 2.6e-19 70.2 0.0 4.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OWF46463.1 - 0.0014 18.6 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Nop25 PF09805.9 OWF46464.1 - 4.1e-14 53.2 11.5 4.1e-14 53.2 11.5 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF2894 PF11445.8 OWF46464.1 - 0.59 10.6 5.2 0.94 9.9 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DB PF01682.19 OWF46465.1 - 5.4e-61 203.1 98.2 1e-14 54.6 11.7 6.8 5 1 1 6 6 6 5 DB module fn3 PF00041.21 OWF46465.1 - 1.5e-50 169.4 20.8 7.1e-11 42.3 0.1 6.7 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 OWF46465.1 - 2.3e-24 85.3 1.7 1.3e-06 28.4 0.1 6.6 5 2 0 5 5 5 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF46465.1 - 9.5e-21 74.2 9.4 9.6e-07 29.3 0.3 5.4 6 1 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 OWF46465.1 - 5.2e-15 55.5 13.7 4.3e-08 33.4 0.8 5.9 6 0 0 6 6 5 3 Immunoglobulin domain ig PF00047.25 OWF46465.1 - 5.9e-14 52.0 2.9 0.00056 20.0 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF46465.1 - 1.5e-12 47.6 4.2 6.9e-07 29.4 0.1 4.8 4 1 0 4 4 4 3 Immunoglobulin V-set domain Tissue_fac PF01108.17 OWF46465.1 - 7.7e-07 28.9 5.2 0.081 12.8 0.1 5.0 4 0 0 4 4 4 2 Tissue factor Pur_ac_phosph_N PF16656.5 OWF46465.1 - 4.9e-05 23.8 23.4 0.14 12.7 0.0 7.7 7 2 0 7 7 7 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF46465.1 - 6.4e-05 23.2 4.0 0.1 12.9 0.0 5.0 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III V-set_CD47 PF08204.11 OWF46465.1 - 0.0045 17.0 2.2 0.58 10.1 0.1 3.7 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Arylsulfotran_N PF17425.2 OWF46465.1 - 1.8 8.6 11.0 3.7 7.6 0.1 4.4 5 0 0 5 5 5 0 Arylsulfotransferase Ig-like domain Nop PF01798.18 OWF46466.1 - 6e-80 268.0 0.1 6e-80 268.0 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OWF46466.1 - 1.1e-45 155.5 2.0 2.8e-45 154.1 2.0 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain HHH_2 PF12826.7 OWF46466.1 - 0.086 13.0 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Collagen PF01391.18 OWF46468.1 - 3e-31 107.0 121.2 3.5e-09 36.3 34.9 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) Brix PF04427.18 OWF46469.1 - 1.9e-46 158.7 2.3 1.9e-46 158.7 2.3 1.6 2 0 0 2 2 2 1 Brix domain FAM86 PF14904.6 OWF46470.1 - 1.8e-20 72.8 0.0 3.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function Methyltransf_16 PF10294.9 OWF46470.1 - 4.5e-18 65.6 0.4 2.6e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 OWF46470.1 - 0.0017 17.9 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TcpQ PF10671.9 OWF46470.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q UQ_con PF00179.26 OWF46471.1 - 4.1e-37 126.9 0.0 5.6e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Reticulon PF02453.17 OWF46472.1 - 0.00018 21.5 2.9 0.00029 20.9 2.9 1.3 1 0 0 1 1 1 1 Reticulon Peptidase_M50B PF13398.6 OWF46472.1 - 0.0041 16.8 4.8 0.19 11.3 0.8 2.1 2 0 0 2 2 2 2 Peptidase M50B-like HXXEE PF13787.6 OWF46472.1 - 0.33 11.8 5.0 1.7 9.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF2207 PF09972.9 OWF46472.1 - 1.8 7.2 3.9 0.69 8.6 0.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) FA_hydroxylase PF04116.13 OWF46472.1 - 2.6 8.4 7.3 0.21 11.9 0.4 2.2 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Bromodomain PF00439.25 OWF46473.1 - 5.1e-25 87.4 1.8 9.4e-25 86.5 0.2 2.3 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 OWF46473.1 - 1.5e-23 82.4 41.0 2.6e-08 33.6 6.8 3.6 3 0 0 3 3 3 3 PHD-finger DDT PF02791.17 OWF46473.1 - 3.3e-12 46.5 0.4 8.5e-12 45.2 0.4 1.8 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 OWF46473.1 - 5.7e-07 29.9 1.9 5.7e-07 29.9 1.9 5.1 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 OWF46473.1 - 3.1e-06 26.6 0.3 1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Shikimate_DH PF01488.20 OWF46473.1 - 0.076 13.1 2.1 0.35 10.9 0.5 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4428 PF14471.6 OWF46473.1 - 0.6 10.1 4.3 32 4.6 2.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ADK_lid PF05191.14 OWF46473.1 - 0.95 9.5 3.6 4.6 7.3 3.6 2.2 1 0 0 1 1 1 0 Adenylate kinase, active site lid Thioredoxin_16 PF18569.1 OWF46474.1 - 4.3e-26 90.9 0.1 1.2e-25 89.4 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain GST_C PF00043.25 OWF46474.1 - 3.1e-06 27.3 0.0 3.1e-06 27.3 0.0 3.0 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OWF46474.1 - 0.00024 20.8 0.0 0.00068 19.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF46474.1 - 0.00044 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF46474.1 - 0.0074 16.5 2.6 0.0083 16.3 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PIG-X PF08320.12 OWF46475.1 - 2.1e-28 99.7 0.0 2.7e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 Snf7 PF03357.21 OWF46476.1 - 1.8e-37 128.6 21.4 1.8e-37 128.6 21.4 1.3 1 1 0 1 1 1 1 Snf7 Prominin PF05478.11 OWF46476.1 - 0.057 11.4 7.3 0.071 11.1 7.3 1.1 1 0 0 1 1 1 0 Prominin APG12 PF04110.13 OWF46477.1 - 1.3e-34 118.5 0.0 1.7e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 OWF46477.1 - 1.7e-05 25.0 0.0 2.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like WD40 PF00400.32 OWF46478.1 - 2.1e-34 116.9 26.1 5e-05 24.0 0.1 11.2 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46478.1 - 1e-08 35.4 6.5 1.2 9.5 0.0 7.5 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF46478.1 - 6.3e-05 22.4 8.5 0.17 11.2 0.0 4.6 4 1 0 4 4 4 2 WD40-like domain RCC1_2 PF13540.6 OWF46478.1 - 0.066 13.0 1.5 17 5.3 0.0 4.1 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat Forkhead PF00250.18 OWF46479.1 - 2.1e-41 140.1 0.2 3.8e-41 139.2 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OWF46479.1 - 7.9e-08 32.5 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain ATG_C PF09333.11 OWF46479.1 - 0.012 15.9 3.8 0.52 10.7 0.3 2.7 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain Linker_histone PF00538.19 OWF46479.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family Tektin PF03148.14 OWF46480.1 - 2.1e-147 490.9 35.4 2.4e-147 490.7 35.4 1.0 1 0 0 1 1 1 1 Tektin family Filament PF00038.21 OWF46480.1 - 0.0081 15.8 14.8 0.0081 15.8 14.8 2.9 2 1 0 2 2 2 1 Intermediate filament protein Prefoldin PF02996.17 OWF46480.1 - 0.027 14.4 3.1 0.027 14.4 3.1 3.5 4 1 0 4 4 4 0 Prefoldin subunit DUF1798 PF08807.10 OWF46480.1 - 0.44 10.7 6.9 0.81 9.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) DUF1664 PF07889.12 OWF46480.1 - 1.9 8.6 20.6 0.071 13.2 5.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 OWF46480.1 - 3.7 7.1 17.9 0.056 13.0 3.2 3.5 3 1 1 4 4 4 0 fzo-like conserved region DUF4693 PF15764.5 OWF46481.1 - 2.3e-09 37.3 1.5 4.6e-05 23.2 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4693) RRM_1 PF00076.22 OWF46482.1 - 5.6e-14 51.7 0.0 1.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 OWF46482.1 - 2.9e-08 33.3 3.2 5.6e-08 32.3 2.7 1.8 2 0 0 2 2 2 1 SAP domain RRM_5 PF13893.6 OWF46482.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fer4_11 PF13247.6 OWF46483.1 - 0.032 14.3 0.5 0.057 13.5 0.5 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain p450 PF00067.22 OWF46485.1 - 8.6e-30 103.9 0.0 1.1e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MAT1-1-2 PF17043.5 OWF46485.1 - 0.034 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function Ank_4 PF13637.6 OWF46486.1 - 6.6e-19 68.0 0.1 4.3e-12 46.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF46486.1 - 1.6e-17 63.8 0.1 3e-09 37.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF46486.1 - 2.2e-16 59.5 6.0 2.6e-07 30.8 0.2 3.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OWF46486.1 - 7.6e-16 58.0 0.1 3.6e-11 43.1 0.0 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46486.1 - 1.6e-14 52.5 0.1 2.7e-07 30.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Glycos_transf_1 PF00534.20 OWF46487.1 - 9.9e-08 31.7 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OWF46487.1 - 2.2e-07 31.1 0.0 3.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OWF46487.1 - 7.9e-06 26.3 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OWF46487.1 - 0.0019 18.5 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OWF46487.1 - 0.003 18.0 0.0 0.0051 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Ldl_recept_a PF00057.18 OWF46488.1 - 2.2e-30 104.6 43.4 7.4e-11 42.1 7.7 3.2 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_a PF00057.18 OWF46489.1 - 8.5e-66 217.9 109.9 1.8e-12 47.3 11.5 7.2 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 OWF46489.1 - 8.6e-40 135.0 3.9 2.8e-13 50.1 0.0 4.5 4 0 0 4 4 4 4 Low-density lipoprotein receptor repeat class B SGL PF08450.12 OWF46489.1 - 9.3e-05 22.1 4.8 0.045 13.3 0.2 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 OWF46489.1 - 0.0052 16.1 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) Myosin_head PF00063.21 OWF46490.1 - 4e-240 798.7 2.1 4e-240 798.7 2.1 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) MyTH4 PF00784.17 OWF46490.1 - 9.2e-52 174.1 13.1 4.3e-29 101.2 0.3 3.4 3 0 0 3 3 3 2 MyTH4 domain SH3_9 PF14604.6 OWF46490.1 - 2.8e-08 33.5 0.0 6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FERM_M PF00373.18 OWF46490.1 - 5.8e-07 29.9 0.2 7.1e-05 23.2 0.0 3.3 2 0 0 2 2 2 1 FERM central domain SH3_2 PF07653.17 OWF46490.1 - 1.4e-06 27.9 0.0 3.4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 OWF46490.1 - 1e-05 24.9 10.7 0.0079 15.9 0.1 3.7 3 0 0 3 3 3 2 IQ calmodulin-binding motif SH3_1 PF00018.28 OWF46490.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 SH3 domain AAA_22 PF13401.6 OWF46490.1 - 0.19 12.0 2.9 0.55 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OWF46490.1 - 0.36 11.3 0.0 0.36 11.3 0.0 3.0 3 0 0 3 3 3 0 ABC transporter MCM6_C PF18263.1 OWF46490.1 - 0.57 10.4 7.8 7.4 6.9 5.4 3.3 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain Sulfotransfer_1 PF00685.27 OWF46491.1 - 7.9e-16 58.3 0.5 7.2e-15 55.2 0.5 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF46491.1 - 1e-11 45.7 0.2 2e-10 41.4 0.2 2.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 OWF46491.1 - 0.0033 17.3 0.1 0.0065 16.3 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 OWF46491.1 - 0.0065 16.4 2.3 0.011 15.6 2.3 1.4 1 0 0 1 1 1 1 Sulfotransferase family Arm PF00514.23 OWF46492.1 - 3.9e-20 71.2 8.4 3.5e-06 26.8 0.0 7.8 7 1 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OWF46492.1 - 1.4e-08 35.0 3.1 0.0032 18.0 0.0 5.8 6 1 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 OWF46492.1 - 1.5e-07 31.7 5.4 0.16 12.4 0.0 6.2 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 OWF46492.1 - 7.6e-06 25.8 1.5 13 6.4 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Atx10homo_assoc PF09759.9 OWF46492.1 - 0.0016 18.5 2.4 0.0091 16.0 0.0 3.3 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 OWF46492.1 - 0.059 13.6 0.5 24 5.2 0.0 4.7 4 2 3 7 7 7 0 Rapamycin-insensitive companion of mTOR, domain 5 RTTN_N PF14726.6 OWF46492.1 - 0.19 12.5 9.0 4.7 8.1 0.0 5.1 4 2 2 6 6 6 0 Rotatin, an armadillo repeat protein, centriole functioning V-ATPase_H_C PF11698.8 OWF46492.1 - 1.7 8.8 12.0 7.9 6.6 0.0 4.8 4 2 0 5 5 5 0 V-ATPase subunit H SH3_9 PF14604.6 OWF46493.1 - 1.1e-42 143.6 0.8 7.4e-16 57.7 0.2 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 OWF46493.1 - 2.6e-36 123.0 0.3 3.2e-11 42.7 0.0 3.7 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 OWF46493.1 - 1.5e-28 98.2 3.6 1.1e-12 47.5 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.16 OWF46493.1 - 7.9e-19 67.2 0.9 7.9e-19 67.2 0.9 2.3 2 0 0 2 2 2 1 Sorbin homologous domain PDZ_6 PF17820.1 OWF46493.1 - 1.9e-06 27.6 0.3 5e-06 26.3 0.3 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF46493.1 - 4.9e-06 26.8 0.4 1.9e-05 24.9 0.4 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF46493.1 - 0.074 13.4 0.1 0.38 11.1 0.1 2.2 1 0 0 1 1 1 0 PDZ domain OCD_Mu_crystall PF02423.15 OWF46494.1 - 2.3e-76 256.8 0.1 2.8e-76 256.5 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OWF46494.1 - 1.7e-07 31.3 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OWF46494.1 - 0.00036 21.1 0.1 0.0016 19.0 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OWF46494.1 - 0.02 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 OWF46494.1 - 0.073 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GFO_IDH_MocA PF01408.22 OWF46494.1 - 0.086 13.7 0.0 0.19 12.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Nucleopor_Nup85 PF07575.13 OWF46495.1 - 3.5e-164 547.5 17.9 4e-164 547.3 17.9 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin FAM181 PF15238.6 OWF46496.1 - 7.1e-05 22.8 0.1 0.00012 22.1 0.1 1.3 1 0 0 1 1 1 1 FAM181 RRM_1 PF00076.22 OWF46498.1 - 1.3e-09 37.7 0.0 2.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THUMP PF02926.17 OWF46499.1 - 5.2e-16 59.1 0.1 1.1e-15 58.0 0.1 1.6 1 0 0 1 1 1 1 THUMP domain RRP36 PF06102.12 OWF46499.1 - 0.015 15.3 1.7 0.015 15.3 1.7 1.7 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF1824 PF08854.10 OWF46499.1 - 0.03 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Pentapeptide_3 PF13576.6 OWF46499.1 - 4.3 7.6 8.0 18 5.6 0.6 3.4 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) zf-B_box PF00643.24 OWF46500.1 - 4.1e-05 23.6 4.7 4.1e-05 23.6 4.7 2.1 2 0 0 2 2 2 1 B-box zinc finger NHL PF01436.21 OWF46500.1 - 0.0014 18.5 1.2 23 5.2 0.0 5.2 5 0 0 5 5 5 2 NHL repeat Ank_4 PF13637.6 OWF46501.1 - 1.3e-07 32.0 0.0 3.7e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) fn3 PF00041.21 OWF46501.1 - 1.6e-07 31.5 0.0 3.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain RA PF00788.23 OWF46501.1 - 9.1e-06 26.2 0.1 3.3e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ank_5 PF13857.6 OWF46501.1 - 2.4e-05 24.5 0.0 0.01 16.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF46501.1 - 0.00058 20.4 0.0 0.0018 18.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF46501.1 - 0.031 14.8 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat T4SS PF07996.11 OWF46501.1 - 0.32 11.4 4.1 6.1 7.2 0.1 3.6 4 0 0 4 4 4 0 Type IV secretion system proteins Dicty_spore_N PF04562.12 OWF46502.1 - 0.00013 22.6 82.2 16 6.2 4.4 8.6 1 1 4 5 5 5 3 Dictyostelium spore coat protein, N terminus Dicty_spore_N PF04562.12 OWF46503.1 - 0.16 12.7 68.9 12 6.6 9.2 5.4 1 1 4 5 5 5 0 Dictyostelium spore coat protein, N terminus GTP_EFTU PF00009.27 OWF46504.1 - 2e-43 148.2 0.0 2.6e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OWF46504.1 - 4.1e-31 107.6 0.1 4.1e-31 107.6 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OWF46504.1 - 5.6e-07 29.9 0.4 2.2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF46504.1 - 0.0016 18.5 0.0 0.007 16.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 OWF46504.1 - 0.015 14.9 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Cob_adeno_trans PF01923.18 OWF46504.1 - 0.025 14.7 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF5096 PF17019.5 OWF46504.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) PAM2 PF07145.15 OWF46504.1 - 0.66 9.8 9.6 0.062 13.0 0.9 3.0 3 0 0 3 3 3 0 Ataxin-2 C-terminal region LUC7 PF03194.15 OWF46505.1 - 3.2e-81 272.7 41.0 3.2e-81 272.7 41.0 3.4 1 1 2 3 3 3 1 LUC7 N_terminus Pro_isomerase PF00160.21 OWF46507.1 - 2.7e-46 157.7 0.4 3.2e-46 157.5 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_1 PF00036.32 OWF46508.1 - 6.1e-24 81.7 7.8 6.1e-06 25.4 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 OWF46508.1 - 9.4e-22 77.3 3.3 5.4e-09 36.4 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF46508.1 - 1.4e-19 68.2 4.7 0.00014 21.5 0.0 4.7 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF46508.1 - 7.6e-17 60.9 3.8 1.4e-07 31.2 0.0 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF46508.1 - 1.5e-16 59.1 3.9 0.00027 20.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OWF46508.1 - 0.034 14.5 0.3 73 3.8 0.1 4.0 3 2 0 3 3 3 0 EF-hand domain EF-hand_2 PF09068.11 OWF46508.1 - 0.051 13.7 0.0 8.4 6.6 0.0 2.8 4 0 0 4 4 4 0 EF hand PhyH PF05721.13 OWF46509.1 - 1.3e-30 107.3 0.0 3.2e-30 106.0 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Amidohydro_2 PF04909.14 OWF46509.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase DIX PF00778.17 OWF46510.1 - 5.7e-30 103.0 0.0 1.3e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 OWF46510.1 - 8.4e-21 74.4 0.4 2.3e-20 73.0 0.4 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 OWF46510.1 - 2.3e-12 46.8 1.8 2.3e-12 46.8 1.8 4.3 4 0 0 4 4 4 1 Axin beta-catenin binding domain AXIN1_TNKS_BD PF16646.5 OWF46510.1 - 4.2e-07 30.8 13.7 2.7e-06 28.2 0.6 4.2 3 1 1 4 4 4 2 Axin-1 tankyrase binding domain DUF445 PF04286.12 OWF46510.1 - 0.092 12.5 4.4 0.18 11.6 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) NusB PF01029.18 OWF46510.1 - 0.13 12.5 0.7 0.28 11.4 0.7 1.5 1 0 0 1 1 1 0 NusB family KN_motif PF12075.8 OWF46511.1 - 0.15 11.9 1.9 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 KN motif fn3 PF00041.21 OWF46512.1 - 0.00022 21.5 0.0 0.00036 20.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain TMEM51 PF15345.6 OWF46512.1 - 0.052 13.4 0.0 0.06 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 GAPT PF11770.8 OWF46512.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) Cu2_monooxygen PF01082.20 OWF46513.1 - 7.8e-29 100.5 0.0 1.6e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF46513.1 - 1e-23 83.6 0.0 3.3e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DUF596 PF04591.12 OWF46514.1 - 0.057 13.6 8.8 34 4.7 0.0 4.8 3 2 2 5 5 5 0 Protein of unknown function, DUF596 DUF596 PF04591.12 OWF46515.1 - 0.017 15.3 4.4 31 4.8 0.0 4.7 3 1 2 5 5 5 0 Protein of unknown function, DUF596 LisH PF08513.11 OWF46515.1 - 0.12 12.4 4.2 77 3.5 0.1 5.3 6 0 0 6 6 6 0 LisH Importin_rep PF18773.1 OWF46515.1 - 0.37 10.5 9.9 6.6 6.5 0.3 5.4 8 0 0 8 8 8 0 Importin 13 repeat Ank_2 PF12796.7 OWF46516.1 - 4.4e-19 68.9 0.4 1.5e-07 31.9 0.3 4.1 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF46516.1 - 2.1e-16 60.1 0.2 9.4e-06 26.1 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF46516.1 - 1.5e-15 57.1 0.6 3.6e-05 24.0 0.1 5.5 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46516.1 - 5e-13 48.0 2.6 0.026 15.0 0.1 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 OWF46516.1 - 4.1e-07 30.1 8.2 0.036 14.5 0.2 4.8 6 0 0 6 6 6 3 Ankyrin repeat SOCS_box PF07525.16 OWF46516.1 - 6.1e-07 29.7 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 SOCS box DUF2520 PF10728.9 OWF46516.1 - 0.13 12.0 0.2 0.61 9.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) CAP PF00188.26 OWF46517.1 - 8.9e-19 68.6 2.2 1.5e-18 67.8 2.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SurA_N_2 PF13623.6 OWF46517.1 - 0.00051 19.9 0.7 0.00074 19.4 0.7 1.4 1 1 0 1 1 1 1 SurA N-terminal domain SurA_N_3 PF13624.6 OWF46517.1 - 0.03 14.1 0.5 0.046 13.5 0.5 1.4 1 1 0 1 1 1 0 SurA N-terminal domain WG_beta_rep PF14903.6 OWF46517.1 - 0.083 13.2 0.0 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 WG containing repeat 3-alpha PF03475.14 OWF46517.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 3-alpha domain RasGAP PF00616.19 OWF46518.1 - 7.5e-26 91.1 0.2 3.9e-15 56.1 0.0 4.4 4 2 1 5 5 5 2 GTPase-activator protein for Ras-like GTPase DUF3498 PF12004.8 OWF46518.1 - 1.8e-19 70.4 45.0 1.8e-19 70.4 45.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3498) C2 PF00168.30 OWF46518.1 - 1.2e-08 35.2 0.2 4.8e-08 33.2 0.2 2.1 1 0 0 1 1 1 1 C2 domain PH PF00169.29 OWF46518.1 - 0.0035 17.8 0.2 0.017 15.7 0.1 2.3 2 0 0 2 2 2 1 PH domain DUF836 PF05768.14 OWF46518.1 - 0.0068 16.8 1.9 1.7 9.1 0.1 2.9 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) GFA PF04828.14 OWF46518.1 - 0.11 12.9 0.0 0.96 9.8 0.0 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme HAUS6_N PF14661.6 OWF46518.1 - 0.26 10.8 5.8 0.81 9.2 5.8 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.13 OWF46518.1 - 0.6 9.3 5.5 1.7 7.8 5.5 1.7 1 0 0 1 1 1 0 TMPIT-like protein FliD_C PF07195.12 OWF46518.1 - 1.1 8.6 10.2 0.2 11.0 5.7 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF745 PF05335.13 OWF46518.1 - 2 8.1 8.7 7.7 6.2 7.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Apolipoprotein PF01442.18 OWF46519.1 - 0.00021 21.2 4.4 0.00079 19.4 0.0 2.7 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain COG5 PF10392.9 OWF46519.1 - 0.049 13.8 0.1 0.049 13.8 0.1 2.9 2 1 0 2 2 2 0 Golgi transport complex subunit 5 COBRA1 PF06209.13 OWF46520.1 - 1.4e-174 581.4 8.3 1.2e-168 561.8 3.6 2.2 1 1 1 2 2 2 2 Cofactor of BRCA1 (COBRA1) DUF5601 PF18151.1 OWF46520.1 - 0.022 15.1 0.5 4.6 7.6 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) EF-G-binding_N PF07299.11 OWF46520.1 - 0.05 14.1 1.0 1.4 9.5 0.0 3.1 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal SLIDE PF09111.10 OWF46520.1 - 0.053 13.6 0.0 0.48 10.5 0.0 2.5 2 0 0 2 2 2 0 SLIDE SH2 PF00017.24 OWF46521.1 - 7.5e-15 54.8 0.0 1.8e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 OWF46521.1 - 1.8e-13 51.1 0.0 3.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain SAM_2 PF07647.17 OWF46521.1 - 7.9e-06 25.9 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF46521.1 - 0.00023 21.5 0.5 0.0022 18.4 0.1 2.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Band_7 PF01145.25 OWF46523.1 - 1.5e-16 60.9 0.0 1.5e-16 60.9 0.0 2.8 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 OWF46523.1 - 6.1e-07 29.7 13.7 6.1e-07 29.7 13.7 3.8 2 2 1 3 3 3 2 Flotillin FAM76 PF16046.5 OWF46523.1 - 2.3 7.5 8.5 3.3 7.0 8.5 1.3 1 0 0 1 1 1 0 FAM76 protein DUF505 PF04458.12 OWF46525.1 - 0.061 11.7 0.6 0.11 10.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF505) RSS_P20 PF11757.8 OWF46525.1 - 0.092 13.2 0.2 0.4 11.2 0.2 2.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain PGBA_C PF15437.6 OWF46525.1 - 2.3 8.6 10.6 0.37 11.2 0.5 3.9 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA C-terminal Bap31_Bap29_C PF18035.1 OWF46525.1 - 3.2 7.8 8.8 6.1 6.9 0.4 3.3 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Ribosomal_L28e PF01778.17 OWF46526.1 - 1e-33 116.5 1.4 1.3e-33 116.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family SPRY PF00622.28 OWF46527.1 - 1.2e-07 31.8 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Acyl-ACP_TE PF01643.17 OWF46528.1 - 2.7e-06 26.9 0.2 3e-06 26.7 0.2 1.4 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF46528.1 - 0.16 12.4 1.1 0.48 10.9 1.1 1.7 1 1 0 1 1 1 0 Thioesterase-like superfamily Radial_spoke PF04712.12 OWF46530.1 - 1.2e-169 565.4 0.0 1.6e-169 565.0 0.0 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein Zona_pellucida PF00100.23 OWF46531.1 - 1.9e-07 31.1 1.5 2.6e-07 30.7 1.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain IgGFc_binding PF17517.2 OWF46532.1 - 1.1e-57 195.5 2.8 1.1e-57 195.5 2.8 1.9 2 0 0 2 2 2 1 IgGFc binding protein ShK PF01549.24 OWF46532.1 - 0.034 14.7 17.7 0.059 13.9 4.6 2.7 2 0 0 2 2 2 0 ShK domain-like NIF PF03031.18 OWF46533.1 - 3.5e-52 176.3 0.8 3.5e-52 176.3 0.8 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF1899 PF08953.11 OWF46534.1 - 1.1e-32 111.7 0.4 2.4e-32 110.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OWF46534.1 - 4.9e-22 77.5 0.2 9.1e-22 76.7 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OWF46534.1 - 5.5e-14 52.3 8.2 1.5e-06 28.8 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46534.1 - 1.2e-05 25.5 0.1 0.0035 17.6 0.1 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CEP209_CC5 PF16574.5 OWF46535.1 - 0.0011 19.1 1.0 0.0017 18.5 1.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 Geminin PF07412.12 OWF46535.1 - 0.032 14.0 1.3 0.044 13.5 1.3 1.3 1 0 0 1 1 1 0 Geminin RseA_C PF03873.13 OWF46535.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Pox_A11 PF05061.13 OWF46535.1 - 0.14 11.4 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein RabGAP-TBC PF00566.18 OWF46536.1 - 1.2e-32 113.3 1.9 1.2e-32 113.3 1.9 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EphA2_TM PF14575.6 OWF46537.1 - 0.024 15.5 0.1 0.063 14.2 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OWF46537.1 - 0.12 12.3 1.9 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 Protocadherin Syndecan PF01034.20 OWF46537.1 - 0.13 12.2 3.1 0.26 11.2 3.1 1.5 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.6 OWF46537.1 - 1.7 7.4 4.8 0.42 9.4 0.1 1.9 2 0 0 2 2 2 0 Amnionless Prominin PF05478.11 OWF46538.1 - 0.25 9.3 5.4 0.31 8.9 5.4 1.1 1 0 0 1 1 1 0 Prominin DUF4064 PF13273.6 OWF46539.1 - 0.16 12.2 0.2 0.68 10.3 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Shisa PF13908.6 OWF46539.1 - 0.36 11.0 26.2 25 5.0 26.2 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 OWF46539.1 - 2.3 7.5 7.1 0.079 12.3 0.6 1.8 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Ets PF00178.22 OWF46540.1 - 2.5e-24 85.6 0.2 4.1e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 Ets-domain DUF913 PF06025.12 OWF46540.1 - 0.037 13.0 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Retinin_C PF04527.12 OWF46541.1 - 0.015 15.6 2.4 3 8.1 0.6 3.7 1 1 1 2 2 2 0 Drosophila Retinin like protein Phage_GPL PF05926.11 OWF46541.1 - 2.5 8.1 11.8 44 4.1 0.2 4.3 1 1 3 4 4 4 0 Phage head completion protein (GPL) Ank_2 PF12796.7 OWF46542.1 - 1.9e-76 252.7 31.5 1.1e-17 64.4 0.5 6.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 OWF46542.1 - 5e-55 186.6 0.0 8.2e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 OWF46542.1 - 9.8e-52 171.3 16.2 2.5e-07 30.9 0.0 11.1 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 OWF46542.1 - 1.9e-49 165.4 10.5 3.9e-12 46.4 0.1 7.5 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46542.1 - 1.7e-46 150.8 8.9 5.9e-05 23.2 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat Pkinase PF00069.25 OWF46542.1 - 2.8e-44 151.5 0.0 4.7e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OWF46542.1 - 7.3e-37 125.0 11.5 7.4e-06 26.1 0.0 9.7 1 1 8 10 10 10 8 Ankyrin repeats (many copies) APH PF01636.23 OWF46542.1 - 0.0023 17.9 0.1 0.004 17.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF46542.1 - 0.04 13.2 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OWF46542.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nitro_FeMo-Co PF02579.17 OWF46542.1 - 0.14 12.5 0.3 7.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor OST-HTH PF12872.7 OWF46544.1 - 9.7e-06 25.3 1.4 0.16 11.8 0.2 3.4 2 1 1 3 3 3 2 OST-HTH/LOTUS domain Utp8 PF10395.9 OWF46544.1 - 0.091 11.2 5.3 0.1 11.1 5.3 1.0 1 0 0 1 1 1 0 Utp8 family Ubie_methyltran PF01209.18 OWF46544.1 - 0.16 11.3 0.6 12 5.1 0.0 2.6 1 1 2 3 3 3 0 ubiE/COQ5 methyltransferase family DNA_ligase_OB_2 PF14743.6 OWF46544.1 - 9.3 6.4 5.2 1.3e+02 2.7 0.4 3.8 4 1 1 5 5 5 0 DNA ligase OB-like domain ShK PF01549.24 OWF46546.1 - 2.6e-26 91.9 234.8 1.8e-05 25.2 9.6 15.5 16 0 0 16 16 15 11 ShK domain-like Pep_M12B_propep PF01562.19 OWF46546.1 - 3.2e-25 89.0 1.8 3.2e-25 89.0 1.8 2.1 3 0 0 3 3 2 1 Reprolysin family propeptide TSP_1 PF00090.19 OWF46546.1 - 1.4e-17 63.6 63.8 1.8e-10 40.9 9.2 7.4 6 0 0 6 6 5 4 Thrombospondin type 1 domain Reprolysin PF01421.19 OWF46546.1 - 6.9e-17 62.0 0.0 1.8e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 OWF46546.1 - 4.7e-14 52.7 4.2 4.7e-14 52.7 4.2 11.0 7 3 2 9 9 5 1 ADAM cysteine-rich domain ADAM_spacer1 PF05986.14 OWF46546.1 - 1.9e-10 40.8 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin_4 PF13583.6 OWF46546.1 - 1.4e-06 28.1 0.3 5.5e-06 26.2 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF46546.1 - 9.6e-06 25.6 0.2 3.3e-05 23.9 0.2 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF46546.1 - 5.6e-05 23.6 0.0 0.00024 21.6 0.0 2.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF46546.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin Glucodextran_B PF09136.10 OWF46546.1 - 0.021 15.2 1.6 7.3 7.0 0.0 3.9 3 0 0 3 3 3 0 Glucodextranase, domain B SR-25 PF10500.9 OWF46546.1 - 7 6.2 14.0 0.51 9.9 8.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OWF46546.1 - 7.2 7.4 14.2 3.6 8.3 10.2 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein EF-hand_7 PF13499.6 OWF46547.1 - 7.4e-12 45.5 7.9 2.7e-07 30.9 2.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF46547.1 - 8.8e-11 40.6 2.7 6e-05 22.3 0.1 3.4 2 1 1 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF46547.1 - 3.3e-09 36.0 5.2 0.0035 17.1 0.0 3.9 2 2 1 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 OWF46547.1 - 1.1e-05 24.7 2.1 0.00014 21.2 0.0 3.2 3 1 1 4 4 4 1 EF hand Dockerin_1 PF00404.18 OWF46547.1 - 7.8e-05 22.8 1.5 3.8 7.8 0.1 3.2 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_8 PF13833.6 OWF46547.1 - 0.073 12.9 2.8 0.085 12.7 0.3 2.4 2 1 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF46547.1 - 0.097 13.0 0.2 0.57 10.5 0.2 2.2 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region CDO_I PF05995.12 OWF46548.1 - 9.5e-12 44.6 0.0 1.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I Prenylcys_lyase PF07156.14 OWF46548.1 - 0.0052 15.9 0.4 0.0057 15.8 0.4 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase GIT_CC PF16559.5 OWF46549.1 - 0.00039 20.2 4.7 0.00039 20.2 4.7 4.0 3 1 1 4 4 4 1 GIT coiled-coil Rho guanine nucleotide exchange factor CALCOCO1 PF07888.11 OWF46549.1 - 0.0016 17.4 34.5 0.0016 17.4 34.5 1.5 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like KASH_CCD PF14662.6 OWF46549.1 - 0.0036 17.2 12.1 0.0036 17.2 12.1 2.9 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 OWF46549.1 - 0.0037 17.4 11.5 0.0037 17.4 11.5 2.8 1 1 0 2 2 2 1 Tropomyosin like TMF_TATA_bd PF12325.8 OWF46549.1 - 0.026 14.7 2.2 0.026 14.7 2.2 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding FPP PF05911.11 OWF46549.1 - 0.29 9.3 37.0 0.0075 14.5 14.7 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Ly49 PF08391.10 OWF46549.1 - 0.86 10.0 22.3 0.83 10.0 4.0 3.2 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region DUF2353 PF09789.9 OWF46549.1 - 1.2 8.4 38.9 0.06 12.7 22.8 2.5 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF1319 PF07028.11 OWF46549.1 - 6.5 7.0 19.8 0.85 9.9 2.7 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1319) HemX PF04375.14 OWF46549.1 - 6.8 5.9 32.5 4.2 6.6 17.6 2.5 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FlaC_arch PF05377.11 OWF46549.1 - 7 7.1 21.0 1.4 9.4 0.5 4.9 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 OWF46549.1 - 7.2 6.5 28.1 1.1 9.1 3.8 4.3 2 2 1 4 4 4 0 Septum formation initiator Atg14 PF10186.9 OWF46549.1 - 8.9 5.3 48.4 0.17 10.9 20.7 3.1 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lipocalin_7 PF14651.6 OWF46550.1 - 1.4e-08 34.7 0.6 1.5e-08 34.6 0.6 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.6 OWF46550.1 - 0.004 18.1 3.2 0.009 17.0 3.2 1.6 1 1 0 1 1 1 1 Lipocalin-like domain DUF4179 PF13786.6 OWF46551.1 - 9.3e-08 32.4 44.1 0.29 11.6 1.9 8.8 1 1 6 7 7 7 7 Domain of unknown function (DUF4179) Flavi_glycop_C PF02832.16 OWF46551.1 - 7e-06 26.1 21.1 2 8.6 0.8 7.8 1 1 7 8 8 8 4 Flavivirus glycoprotein, immunoglobulin-like domain Calycin_like PF13944.6 OWF46551.1 - 6.7 7.0 14.4 20 5.5 0.3 3.8 2 1 2 4 4 4 0 Calycin-like beta-barrel domain Lipocalin_7 PF14651.6 OWF46552.1 - 2e-13 50.4 1.4 2.5e-13 50.1 1.4 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 OWF46552.1 - 7.3e-12 45.7 0.7 8.1e-12 45.5 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Glyco_hydro_16 PF00722.21 OWF46553.1 - 5e-21 75.0 0.2 1.4e-18 67.0 0.1 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 BCDHK_Adom3 PF10436.9 OWF46554.1 - 4.9e-39 133.8 0.6 7.9e-39 133.1 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OWF46554.1 - 1.5e-12 48.0 0.1 4.3e-12 46.5 0.1 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OWF46554.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VRR_NUC PF08774.11 OWF46554.1 - 0.037 14.1 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 VRR-NUC domain Ion_trans PF00520.31 OWF46555.1 - 1.2e-29 103.3 25.6 1.3e-29 103.2 23.7 1.8 1 1 1 2 2 2 2 Ion transport protein BTB_2 PF02214.22 OWF46555.1 - 2.5e-25 88.7 0.6 9.9e-25 86.7 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF46555.1 - 9.4e-14 51.1 4.1 9.4e-14 51.1 4.1 3.1 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 OWF46555.1 - 0.0098 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Collagen PF01391.18 OWF46556.1 - 8.8e-12 44.6 31.4 5.5e-06 26.1 10.7 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) 3Beta_HSD PF01073.19 OWF46557.1 - 8.1e-59 198.9 0.0 1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OWF46557.1 - 8e-25 87.7 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OWF46557.1 - 2e-13 50.1 0.5 4.2e-11 42.5 0.5 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OWF46557.1 - 3.6e-12 46.0 0.8 1e-11 44.6 0.6 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OWF46557.1 - 6.8e-12 45.4 0.1 2.3e-11 43.7 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OWF46557.1 - 6e-10 39.3 0.1 8.3e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OWF46557.1 - 5.1e-09 35.6 0.0 7.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OWF46557.1 - 3.8e-07 30.2 0.9 1e-06 28.8 0.9 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 OWF46557.1 - 6.5e-05 22.6 0.4 9.3e-05 22.1 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 OWF46557.1 - 0.00029 21.1 0.2 0.00051 20.3 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 OWF46557.1 - 0.0024 17.4 0.9 0.0033 16.9 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_3 PF03447.16 OWF46557.1 - 0.0079 16.8 0.1 0.18 12.5 0.2 2.2 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OWF46557.1 - 0.015 15.5 0.3 0.027 14.7 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 OWF46557.1 - 0.018 15.2 0.2 0.027 14.5 0.2 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RRM_4 PF10598.9 OWF46557.1 - 0.02 15.2 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 Semialdhyde_dh PF01118.24 OWF46557.1 - 0.039 14.4 0.1 0.08 13.4 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OWF46558.1 - 2.4e-10 39.9 0.0 2.6e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OWF46558.1 - 1.9e-06 27.5 0.0 2.1e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF46558.1 - 0.0014 18.1 0.0 0.0015 18.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OWF46558.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 OWF46558.1 - 0.047 12.9 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 OWF46558.1 - 0.16 11.9 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 OWF46558.1 - 0.23 10.9 0.0 0.27 10.7 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 OWF46559.1 - 8.5e-19 67.6 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family C2 PF00168.30 OWF46560.1 - 1.4e-28 99.2 0.3 6.2e-18 65.0 0.0 4.6 3 1 1 4 4 4 2 C2 domain Membr_traf_MHD PF10540.9 OWF46560.1 - 0.0011 19.2 0.0 0.0041 17.3 0.0 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DOCK-C2 PF14429.6 OWF46560.1 - 0.0026 17.6 0.1 0.0064 16.3 0.1 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins T3SS_needle_E PF08988.10 OWF46560.1 - 1 9.6 3.4 0.58 10.4 0.3 2.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle V-SNARE_C PF12352.8 OWF46561.1 - 2.1e-05 24.7 6.7 7.5e-05 22.9 1.2 2.8 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 OWF46561.1 - 4e-05 23.6 5.7 0.00055 19.9 2.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF5089) DUF1664 PF07889.12 OWF46561.1 - 0.0038 17.3 2.2 0.14 12.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 OWF46561.1 - 0.014 15.8 2.5 1.9 9.0 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SNARE PF05739.19 OWF46561.1 - 0.039 14.0 4.9 1.3 9.1 0.6 2.7 2 0 0 2 2 2 0 SNARE domain DUF16 PF01519.16 OWF46561.1 - 0.046 14.2 1.7 7.2 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 OWF46561.1 - 0.053 12.4 2.1 0.096 11.5 0.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DASH_Duo1 PF08651.10 OWF46561.1 - 0.058 13.2 2.8 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 Osmo_CC PF08946.10 OWF46561.1 - 0.078 13.2 0.3 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Laminin_II PF06009.12 OWF46561.1 - 0.089 12.8 2.6 2.6 8.1 0.1 2.5 2 1 0 2 2 2 0 Laminin Domain II XhlA PF10779.9 OWF46561.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.9 3 0 0 3 3 3 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 OWF46561.1 - 0.18 11.8 1.9 0.3 11.1 0.2 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 OWF46561.1 - 0.56 10.5 3.3 2.3 8.6 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 OWF46561.1 - 0.56 10.6 3.2 2.6 8.5 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 OWF46561.1 - 0.94 9.9 4.2 1.8 9.1 0.7 2.3 2 0 0 2 2 2 0 Snapin/Pallidin SlyX PF04102.12 OWF46561.1 - 2.8 8.6 5.0 11 6.7 0.3 3.0 2 1 1 3 3 3 0 SlyX RhoGAP PF00620.27 OWF46562.1 - 1.1e-44 152.0 0.0 3.9e-44 150.1 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.20 OWF46562.1 - 6.7e-28 98.2 1.4 1.9e-27 96.7 1.4 1.8 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 OWF46562.1 - 0.0014 19.1 1.0 0.0084 16.6 1.0 2.4 1 1 0 1 1 1 1 PH domain TPR_MLP1_2 PF07926.12 OWF46562.1 - 2.6 8.1 5.9 0.51 10.4 0.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lactamase_B_2 PF12706.7 OWF46563.1 - 2.1e-05 24.2 0.9 8.8e-05 22.1 0.9 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF46563.1 - 0.0057 16.7 0.2 0.019 15.0 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily OrsD PF12013.8 OWF46563.1 - 0.046 14.2 3.9 1.2 9.7 2.6 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Branch PF02485.21 OWF46564.1 - 9.1e-37 126.9 0.1 1.2e-36 126.5 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WD40 PF00400.32 OWF46566.1 - 1.9e-59 196.2 20.0 1.1e-07 32.4 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46566.1 - 1.6e-13 50.8 2.6 0.17 12.2 0.1 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF46566.1 - 1.1e-07 30.9 6.3 0.42 9.2 0.0 5.6 3 2 2 6 6 6 4 Nucleoporin Nup120/160 LisH PF08513.11 OWF46566.1 - 2.1e-05 24.3 0.2 4.2e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 LisH Pox_A_type_inc PF04508.12 OWF46566.1 - 0.041 13.7 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Methyltransf_10 PF05971.12 OWF46567.1 - 1.2e-37 129.9 0.0 2.2e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 OWF46567.1 - 0.03 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Abhydrolase_1 PF00561.20 OWF46568.1 - 4.4e-28 98.6 0.2 1.1e-21 77.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF46568.1 - 3.8e-17 62.4 0.1 5.6e-17 61.8 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF46568.1 - 6.3e-17 62.9 0.0 7.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OWF46568.1 - 3e-08 32.7 0.0 7.2e-08 31.5 0.0 1.5 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.13 OWF46568.1 - 5e-08 32.9 0.3 2.7e-05 24.0 0.3 2.3 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OWF46568.1 - 6.9e-05 23.1 0.0 9.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 OWF46568.1 - 0.00025 20.8 0.0 0.00047 19.9 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.16 OWF46568.1 - 0.0012 18.4 0.2 0.0028 17.2 0.2 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Palm_thioest PF02089.15 OWF46568.1 - 0.0022 17.9 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 OWF46568.1 - 0.0042 16.6 0.2 0.01 15.3 0.2 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PAF-AH_p_II PF03403.13 OWF46568.1 - 0.0052 15.3 0.1 0.78 8.2 0.0 2.3 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II DUF1057 PF06342.12 OWF46568.1 - 0.0055 15.8 0.1 0.0082 15.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 OWF46568.1 - 0.0087 15.0 0.1 0.013 14.4 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OWF46568.1 - 0.0093 15.0 0.0 0.045 12.7 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.11 OWF46568.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OWF46568.1 - 0.017 14.7 0.0 1.7 8.1 0.0 2.9 2 1 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.15 OWF46568.1 - 0.025 13.8 0.0 0.061 12.5 0.1 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 OWF46568.1 - 0.026 14.4 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1100 PF06500.11 OWF46568.1 - 0.039 12.8 0.2 0.058 12.2 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF2048 PF09752.9 OWF46568.1 - 0.045 12.9 0.0 0.18 10.9 0.0 2.0 1 1 1 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_3 PF07859.13 OWF46568.1 - 0.058 13.2 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF46568.1 - 0.062 12.8 0.0 0.7 9.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OWF46568.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 OWF46568.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase zf-met PF12874.7 OWF46568.1 - 0.13 12.7 0.6 0.4 11.2 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TPR_2 PF07719.17 OWF46569.1 - 4.1e-09 35.8 2.6 0.0011 18.9 1.9 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 OWF46569.1 - 2.5e-07 30.9 0.0 5.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 OWF46569.1 - 1.7e-05 24.5 2.4 0.02 14.7 2.6 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF46569.1 - 4.9e-05 22.9 4.5 0.0092 15.7 4.8 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 OWF46569.1 - 0.0016 19.1 0.6 0.28 11.9 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46569.1 - 0.0043 17.5 1.3 5.2 7.7 0.5 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat CCG PF02754.16 OWF46569.1 - 0.024 14.8 0.1 0.076 13.2 0.1 1.9 1 0 0 1 1 1 0 Cysteine-rich domain TPR_17 PF13431.6 OWF46569.1 - 0.094 13.1 0.3 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF46569.1 - 0.098 13.0 0.2 0.37 11.1 0.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46569.1 - 0.18 11.7 0.5 0.42 10.5 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TIG PF01833.24 OWF46570.1 - 0.00087 19.3 0.3 0.31 11.1 0.2 2.9 1 1 2 3 3 3 3 IPT/TIG domain DUF4813 PF16072.5 OWF46571.1 - 2.3e-10 40.6 17.3 0.73 9.4 0.1 9.0 1 1 6 9 9 9 8 Domain of unknown function (DUF4813) Drf_FH1 PF06346.12 OWF46571.1 - 1.3e-06 28.2 74.9 0.12 12.1 7.1 6.7 1 1 5 6 6 6 6 Formin Homology Region 1 Mlh1_C PF16413.5 OWF46572.1 - 0.18 11.1 0.6 23 4.2 0.1 4.0 2 2 1 4 4 4 0 DNA mismatch repair protein Mlh1 C-terminus DUF4088 PF13317.6 OWF46572.1 - 1.1 8.8 9.0 2.5 7.6 0.1 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF4088) ICMT PF04140.14 OWF46572.1 - 1.6 9.2 25.9 13 6.3 0.3 8.8 1 1 15 16 16 16 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-CRD PF17979.1 OWF46573.1 - 2.8e-16 60.0 44.2 0.014 15.5 8.7 9.7 9 1 0 9 9 9 7 Cysteine rich domain with multizinc binding regions zf-C2H2_4 PF13894.6 OWF46573.1 - 1.7e-11 43.9 113.1 0.099 13.5 0.8 12.7 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF46573.1 - 1.1e-08 35.1 114.0 0.0083 16.5 0.7 12.6 12 0 0 12 12 12 9 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF46573.1 - 0.00011 21.9 15.5 0.002 17.8 3.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-met PF12874.7 OWF46573.1 - 0.0048 17.3 90.2 0.74 10.3 0.1 12.4 12 0 0 12 12 12 7 Zinc-finger of C2H2 type DUF2884 PF11101.8 OWF46573.1 - 4.3 6.8 10.7 0.71 9.3 6.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) BDV_P24 PF06595.11 OWF46574.1 - 5.3e-07 29.7 3.4 0.038 13.9 0.1 4.1 1 1 3 4 4 4 4 Borna disease virus P24 protein DUF16 PF01519.16 OWF46574.1 - 6e-05 23.5 0.2 0.33 11.4 0.1 3.1 1 1 1 2 2 2 2 Protein of unknown function DUF16 Exonuc_VII_S PF02609.16 OWF46574.1 - 0.00087 19.3 4.8 38 4.5 0.0 6.0 2 2 3 6 6 6 0 Exonuclease VII small subunit Sigma_1s PF02454.16 OWF46574.1 - 0.0044 17.0 1.1 4.1 7.4 0.1 2.8 1 1 1 3 3 3 2 Sigma 1s protein DASH_Spc19 PF08287.11 OWF46574.1 - 0.0099 15.8 11.0 7.5 6.4 0.2 5.1 1 1 3 5 5 5 2 Spc19 RIH_assoc PF08454.11 OWF46574.1 - 0.012 15.4 5.2 30 4.5 5.2 3.9 1 1 0 1 1 1 0 RyR and IP3R Homology associated YkyA PF10368.9 OWF46574.1 - 0.1 12.3 0.3 6.4 6.4 0.0 2.4 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein BLOC1_2 PF10046.9 OWF46574.1 - 0.17 12.2 9.8 18 5.7 5.3 3.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT20 PF14931.6 OWF46574.1 - 0.2 11.9 6.8 8.4 6.6 0.3 3.5 1 1 3 4 4 4 0 Intraflagellar transport complex B, subunit 20 DUF1465 PF07323.12 OWF46574.1 - 0.69 9.7 2.2 33 4.3 0.1 3.5 1 1 1 4 4 4 0 Protein of unknown function (DUF1465) DUF2193 PF09959.9 OWF46574.1 - 1 7.7 3.8 1.3 7.4 2.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) DUF1041 PF06292.17 OWF46574.1 - 1.8 9.0 6.5 62 4.1 0.2 3.6 1 1 3 4 4 4 0 Domain of Unknown Function (DUF1041) DUF211 PF02680.14 OWF46574.1 - 2.4 8.4 8.7 7.8 6.7 3.8 2.7 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 CAAP1 PF15335.6 OWF46575.1 - 2.1e-21 76.2 2.1 3e-21 75.7 2.1 1.3 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 Tim54 PF11711.8 OWF46575.1 - 0.044 12.6 4.2 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 EspG PF06872.11 OWF46575.1 - 0.046 12.3 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 EspG protein TetR_C_8 PF14278.6 OWF46575.1 - 0.18 12.0 0.3 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Peptidase_S46 PF10459.9 OWF46575.1 - 0.55 8.8 3.0 0.66 8.6 3.0 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF755 PF05501.11 OWF46575.1 - 0.89 9.8 11.4 1.4 9.2 6.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ku_C PF03730.14 OWF46575.1 - 4.8 7.9 11.3 1.1 10.0 1.4 2.8 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm ATP11 PF06644.11 OWF46575.1 - 6.7 6.4 9.0 5.6 6.7 2.3 2.1 2 0 0 2 2 2 0 ATP11 protein Fibrinogen_C PF00147.18 OWF46576.1 - 9.3e-36 123.7 5.9 6.8e-19 68.6 0.2 2.3 1 1 1 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain CFC PF09443.10 OWF46576.1 - 1.6 8.7 4.7 1.1 9.2 1.3 2.2 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Trypsin_2 PF13365.6 OWF46577.1 - 0.0015 19.4 0.2 0.0051 17.7 0.2 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Ank_5 PF13857.6 OWF46578.1 - 0.19 12.1 0.0 9.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Death PF00531.22 OWF46579.1 - 2.2e-07 30.9 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Death domain DUF2315 PF10231.9 OWF46581.1 - 7.7e-48 161.6 9.4 9.5e-48 161.3 9.4 1.1 1 0 0 1 1 1 1 Apoptogenic protein 1 FliD_N PF02465.18 OWF46581.1 - 0.071 13.8 1.1 0.1 13.3 1.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Homeodomain PF00046.29 OWF46582.1 - 4.3e-22 77.7 3.9 8e-22 76.8 3.9 1.5 1 0 0 1 1 1 1 Homeodomain CD20 PF04103.15 OWF46583.1 - 6.2e-14 52.4 9.4 6.2e-14 52.4 9.4 1.9 1 1 1 2 2 2 1 CD20-like family UbiA PF01040.18 OWF46583.1 - 0.11 11.8 5.8 0.15 11.3 5.8 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Tetraspanin PF00335.20 OWF46583.1 - 0.18 11.5 15.6 0.032 13.9 11.2 1.7 1 1 1 2 2 2 0 Tetraspanin family FIBP PF05427.11 OWF46584.1 - 8.2e-155 515.5 8.4 9.3e-155 515.3 8.4 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Transket_pyr PF02779.24 OWF46585.1 - 7e-61 205.0 0.0 1.1e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OWF46585.1 - 1.2e-44 151.6 0.0 2e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 OWF46585.1 - 5.1e-44 150.4 0.0 8.7e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component PI-TkoII_IV PF18714.1 OWF46585.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV FERM_M PF00373.18 OWF46586.1 - 9.8e-42 142.1 0.0 2.8e-41 140.6 0.0 1.8 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 OWF46586.1 - 2.6e-36 123.7 1.5 8.2e-36 122.1 1.5 1.9 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 OWF46586.1 - 1.9e-07 31.5 0.3 5e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 PH domain FERM_N PF09379.10 OWF46586.1 - 0.015 15.3 0.1 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 FERM N-terminal domain FERM_f0 PF16511.5 OWF46586.1 - 0.029 14.7 0.8 2.1 8.7 0.0 3.4 3 0 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM TPR_2 PF07719.17 OWF46587.1 - 1.9e-27 93.1 20.4 0.00068 19.6 0.2 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46587.1 - 2.4e-23 80.9 26.1 8.5e-06 25.4 0.2 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46587.1 - 1.6e-18 65.3 13.0 0.0074 16.4 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF46587.1 - 2.7e-18 66.0 16.5 0.00043 20.5 0.2 7.7 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46587.1 - 9.3e-14 51.0 10.2 0.28 12.1 0.0 8.5 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46587.1 - 1.6e-12 47.8 14.4 0.0023 18.4 0.3 6.5 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF46587.1 - 3.8e-11 43.4 11.8 8e-07 29.6 0.1 5.6 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46587.1 - 4.2e-10 38.9 11.3 0.044 13.8 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF46587.1 - 8.7e-08 32.3 21.8 0.018 15.3 3.1 5.6 4 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OWF46587.1 - 2.1e-07 31.1 18.5 3.5 8.5 0.0 8.1 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OWF46587.1 - 3.1e-05 24.0 15.0 0.0033 17.7 0.3 6.6 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46587.1 - 0.00013 21.7 6.1 0.53 10.2 0.4 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Glyoxalase PF00903.25 OWF46587.1 - 0.0033 17.6 0.6 0.21 11.8 0.1 2.7 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fis1_TPR_C PF14853.6 OWF46587.1 - 0.0039 17.2 7.4 0.095 12.8 0.1 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 OWF46587.1 - 0.0043 16.5 1.7 0.0084 15.6 0.8 1.9 1 1 0 1 1 1 1 Coatomer epsilon subunit Coatomer_WDAD PF04053.14 OWF46587.1 - 0.0045 16.1 0.0 0.15 11.1 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region TPR_9 PF13371.6 OWF46587.1 - 0.013 15.7 6.7 1.7 8.9 0.2 5.2 5 1 3 8 8 6 0 Tetratricopeptide repeat PPR PF01535.20 OWF46587.1 - 0.027 14.7 2.3 73 4.0 0.1 5.3 6 0 0 6 6 5 0 PPR repeat FAT PF02259.23 OWF46587.1 - 0.043 13.0 2.2 4.2 6.5 0.3 2.6 2 1 0 2 2 2 0 FAT domain SRP_TPR_like PF17004.5 OWF46587.1 - 0.11 12.5 3.1 0.46 10.5 0.5 2.8 2 0 0 2 2 2 0 Putative TPR-like repeat DUF5112 PF17139.4 OWF46587.1 - 0.19 11.2 4.9 1.4 8.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5112) TPR_11 PF13414.6 OWF46587.1 - 0.8 9.4 9.5 5.2 6.8 0.3 5.3 3 1 2 5 5 5 0 TPR repeat WD40 PF00400.32 OWF46588.1 - 1.1e-21 76.8 15.7 5.7e-06 27.0 0.1 6.1 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46588.1 - 2.1e-07 31.1 0.1 0.44 10.9 0.0 4.8 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 OWF46588.1 - 2.9e-05 23.6 0.3 6.5e-05 22.5 0.3 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 OWF46588.1 - 0.00051 19.1 0.0 0.013 14.5 0.0 2.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OWF46588.1 - 0.00063 19.6 2.2 3.9 7.5 0.1 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OWF46588.1 - 0.0014 18.6 0.0 0.1 12.4 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CRR7 PF12095.8 OWF46588.1 - 0.079 13.4 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 Frtz PF11768.8 OWF46588.1 - 0.12 10.7 0.0 0.2 9.9 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Esterase PF00756.20 OWF46589.1 - 0.00077 19.2 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 OWF46589.1 - 0.0023 17.6 0.0 0.0049 16.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF46589.1 - 0.0026 17.1 0.1 0.053 12.8 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 TPR_7 PF13176.6 OWF46589.1 - 0.0056 16.6 0.0 0.032 14.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46589.1 - 0.015 15.5 0.0 0.05 13.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 OWF46589.1 - 0.016 15.0 0.0 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OWF46589.1 - 0.025 14.0 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OWF46589.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TPR_2 PF07719.17 OWF46589.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46589.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 OWF46589.1 - 0.45 11.1 5.8 4.1 7.9 5.8 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Acyltransferase PF01553.21 OWF46590.1 - 7.9e-18 64.4 0.0 1.7e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase UBX PF00789.20 OWF46591.1 - 3.2e-16 59.3 0.0 6.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 OWF46591.1 - 8.1e-09 35.2 0.1 1.7e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Caldesmon PF02029.15 OWF46591.1 - 0.00013 20.9 23.8 0.00016 20.6 23.8 1.1 1 0 0 1 1 1 1 Caldesmon LCD1 PF09798.9 OWF46591.1 - 0.69 8.4 11.9 0.9 8.0 11.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DDHD PF02862.17 OWF46591.1 - 1 9.5 6.5 1.4 9.0 6.5 1.3 1 0 0 1 1 1 0 DDHD domain APG6_N PF17675.1 OWF46591.1 - 1.2 9.6 23.6 2.2 8.8 23.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region U79_P34 PF03064.16 OWF46591.1 - 3.4 6.9 18.6 5.2 6.4 18.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DHHC PF01529.20 OWF46592.1 - 3e-29 101.8 14.0 3e-29 101.8 14.0 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase bZIP_1 PF00170.21 OWF46593.1 - 1.4e-10 41.1 4.0 4e-10 39.6 4.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF46593.1 - 1.8e-05 24.8 3.8 7.3e-05 22.8 3.6 2.1 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF46593.1 - 0.0012 19.4 2.9 0.0034 17.9 2.9 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor Cnn_1N PF07989.11 OWF46593.1 - 0.0017 18.4 0.7 0.007 16.5 0.7 2.1 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 ATG16 PF08614.11 OWF46593.1 - 0.027 14.7 3.4 0.068 13.4 3.4 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 OWF46593.1 - 0.074 13.5 1.2 0.29 11.6 1.2 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 OWF46593.1 - 0.22 12.0 3.3 0.53 10.8 3.3 1.7 1 0 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 OWF46593.1 - 0.68 10.3 3.1 12 6.3 3.1 2.5 1 1 0 1 1 1 0 TSC-22/dip/bun family SNAPc19 PF15497.6 OWF46593.1 - 4 7.9 9.6 0.21 12.1 2.0 2.8 2 1 1 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Lipase_GDSL PF00657.22 OWF46594.1 - 4.5e-22 79.0 0.0 6.9e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF46594.1 - 5.3e-13 49.7 0.1 6.4e-12 46.2 0.1 2.5 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family RNA_pol_I_A49 PF06870.12 OWF46596.1 - 1.2e-80 271.3 0.4 1.5e-80 270.9 0.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF4241 PF14025.6 OWF46596.1 - 0.083 13.2 1.2 0.091 13.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) DUF2040 PF09745.9 OWF46596.1 - 0.39 10.8 5.8 0.88 9.6 2.4 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) NTF2 PF02136.20 OWF46597.1 - 3.6e-19 69.5 0.1 4.2e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 OWF46597.1 - 0.00031 20.7 0.0 0.00037 20.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Ran_BP1 PF00638.18 OWF46598.1 - 5.6e-140 459.3 17.7 1.2e-48 164.4 0.7 4.5 4 0 0 4 4 4 4 RanBP1 domain zf-RanBP PF00641.18 OWF46598.1 - 3.1e-23 80.8 24.7 4.7e-09 35.4 2.9 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Nucleoporin_FG PF13634.6 OWF46598.1 - 9.8e-07 29.5 47.3 3.3e-05 24.6 13.2 9.8 5 2 5 10 10 6 3 Nucleoporin FG repeat region TPR_2 PF07719.17 OWF46598.1 - 1.3e-06 28.1 3.6 0.0079 16.2 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46598.1 - 3.1e-05 23.8 6.2 0.0042 17.2 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46598.1 - 4.1e-05 23.2 5.4 0.00035 20.3 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46598.1 - 0.00019 21.2 5.2 0.0026 17.7 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46598.1 - 0.021 15.3 3.9 2.5 8.7 0.0 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46598.1 - 0.023 15.5 0.2 5.6 8.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Lig_C PF18330.1 OWF46598.1 - 0.024 14.6 4.0 3 7.9 0.0 3.7 4 0 0 4 4 3 0 Ligase Pab1020 C-terminal region PBP1_TM PF14812.6 OWF46598.1 - 0.032 14.6 14.2 0.099 13.0 14.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 OWF46598.1 - 0.1 12.4 12.6 0.3 10.9 12.6 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 OWF46598.1 - 0.1 11.8 10.7 0.21 10.7 10.7 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.11 OWF46598.1 - 0.11 12.5 10.2 0.33 11.0 10.2 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal TPR_12 PF13424.6 OWF46598.1 - 0.16 12.3 5.2 2.3 8.6 0.6 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat YlbE PF14003.6 OWF46598.1 - 0.23 11.9 0.9 5.8 7.4 0.5 2.7 2 0 0 2 2 2 0 YlbE-like protein DNA_pol_phi PF04931.13 OWF46598.1 - 0.88 7.6 24.8 3 5.9 24.8 1.8 1 0 0 1 1 1 0 DNA polymerase phi ANAPC3 PF12895.7 OWF46598.1 - 2 8.7 10.2 0.62 10.3 1.3 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FYDLN_acid PF09538.10 OWF46598.1 - 2.8 8.7 21.7 16 6.2 21.7 2.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CENP-B_dimeris PF09026.10 OWF46598.1 - 7.5 7.0 26.3 25 5.3 26.3 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Malate_synthase PF01274.22 OWF46599.1 - 5.6e-113 378.0 0.0 8.3e-113 377.4 0.0 1.1 1 0 0 1 1 1 1 Malate synthase TFIID_30kDa PF03540.13 OWF46599.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit NARP1 PF12569.8 OWF46600.1 - 6.4e-212 705.0 20.0 6.4e-212 705.0 20.0 1.5 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 OWF46600.1 - 1.7e-18 65.2 7.5 0.0031 17.6 0.0 8.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46600.1 - 2.5e-15 55.8 3.7 0.022 15.5 0.0 7.6 6 2 2 8 8 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OWF46600.1 - 1.4e-12 46.6 21.5 0.0029 17.6 0.2 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OWF46600.1 - 6.1e-11 42.8 0.9 0.44 11.2 0.0 5.7 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46600.1 - 3.5e-10 39.3 9.2 0.042 13.7 0.1 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46600.1 - 6.6e-08 32.9 13.4 0.0022 18.4 0.5 5.9 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 OWF46600.1 - 6.6e-08 32.1 0.1 0.0013 18.4 0.1 4.0 4 0 0 4 4 4 2 TPR repeat TPR_6 PF13174.6 OWF46600.1 - 1.7e-06 28.3 6.1 0.033 14.8 0.0 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF46600.1 - 2.6e-06 27.6 13.0 2.9 8.3 0.3 7.7 6 3 2 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF46600.1 - 3.1e-06 27.3 11.1 0.025 14.8 0.4 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OWF46600.1 - 3.6e-05 23.5 7.3 1.3 9.2 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 OWF46600.1 - 0.00021 21.6 0.3 43 5.2 0.0 5.5 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF46600.1 - 0.0027 17.1 0.3 0.32 10.3 0.1 3.1 3 0 0 3 3 3 1 MalT-like TPR region Mu-like_Pro PF10123.9 OWF46600.1 - 0.0048 16.5 3.7 1.9 7.9 0.0 3.1 3 0 0 3 3 3 2 Mu-like prophage I protein TPR_17 PF13431.6 OWF46600.1 - 0.0048 17.2 3.6 1.2 9.6 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat Vfa1 PF08432.10 OWF46600.1 - 0.056 13.8 10.0 0.14 12.5 10.0 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TPR_9 PF13371.6 OWF46600.1 - 0.093 12.9 2.7 1.4 9.1 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 OWF46600.1 - 0.12 12.7 1.5 38 4.8 0.0 4.4 4 0 0 4 4 3 0 PPR repeat Fis1_TPR_C PF14853.6 OWF46600.1 - 0.14 12.2 5.8 46 4.2 0.0 5.0 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OWF46600.1 - 0.9 9.5 6.4 52 3.9 0.1 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat LpoB PF13036.6 OWF46600.1 - 1.6 8.7 8.2 2.5 8.1 6.6 2.0 2 0 0 2 2 2 0 Peptidoglycan-synthase activator LpoB DUF1682 PF07946.14 OWF46600.1 - 2.5 7.2 12.8 0.29 10.3 8.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.10 OWF46600.1 - 4.2 7.4 8.4 11 6.1 8.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MAS20 PF02064.15 OWF46600.1 - 7.7 6.6 10.1 18 5.4 9.3 2.1 2 0 0 2 2 1 0 MAS20 protein import receptor Ras PF00071.22 OWF46601.1 - 5.2e-52 175.7 0.1 6.5e-52 175.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF46601.1 - 7.9e-34 116.5 0.0 1.3e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF46601.1 - 4.1e-18 65.4 0.1 5.4e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF46601.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF46601.1 - 4.2e-08 33.3 0.0 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF46601.1 - 4.3e-07 29.5 0.1 1.1e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OWF46601.1 - 5.3e-07 29.4 0.3 1.7e-05 24.5 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OWF46601.1 - 1.4e-05 24.5 4.0 0.0006 19.1 0.9 2.7 1 1 1 2 2 2 2 G-protein alpha subunit TniB PF05621.11 OWF46601.1 - 0.0005 19.5 0.0 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein CTD_bind PF04818.13 OWF46603.1 - 9.1e-07 29.6 0.0 2.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf_UBZ PF18439.1 OWF46603.1 - 0.002 17.7 1.6 0.0045 16.6 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Ras PF00071.22 OWF46604.1 - 3.9e-54 182.6 0.1 7.2e-54 181.8 0.1 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF46604.1 - 6.8e-35 119.9 0.0 2.1e-34 118.3 0.0 1.9 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase ASH PF15780.5 OWF46604.1 - 8e-16 58.0 10.2 0.0022 18.2 0.1 10.4 11 1 0 11 11 10 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Arf PF00025.21 OWF46604.1 - 9.4e-12 44.7 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF46604.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PapD-like PF14874.6 OWF46604.1 - 0.00013 22.1 0.0 0.68 10.1 0.0 4.3 4 0 0 4 4 4 1 Flagellar-associated PapD-like MMR_HSR1 PF01926.23 OWF46604.1 - 0.0013 18.8 0.0 0.0039 17.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF46604.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 OWF46604.1 - 0.045 13.9 0.1 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF46604.1 - 0.061 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 OWF46604.1 - 0.069 13.1 0.4 10 6.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OWF46604.1 - 0.078 13.2 0.1 0.3 11.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF46604.1 - 0.082 13.3 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 OWF46604.1 - 0.15 12.1 0.3 0.96 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF229 PF02995.17 OWF46605.1 - 4.1e-119 398.4 0.5 8.6e-119 397.4 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF46605.1 - 1.9e-10 40.7 0.3 3.1e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF46605.1 - 0.17 11.4 1.0 1.5 8.3 1.0 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase LRR_6 PF13516.6 OWF46606.1 - 2.9e-19 67.4 21.4 0.0014 18.6 0.0 8.8 8 0 0 8 8 8 7 Leucine Rich repeat EF-hand_7 PF13499.6 OWF46606.1 - 2.6e-08 34.2 2.4 7.7e-08 32.7 2.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF46606.1 - 3.3e-08 32.5 1.9 0.00036 19.9 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF46606.1 - 7.2e-08 32.2 0.9 0.0064 16.3 0.3 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF46606.1 - 1.1e-07 31.1 2.6 0.00056 19.6 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain LRR_1 PF00560.33 OWF46606.1 - 6.9e-07 28.9 6.2 6.9 7.6 0.0 8.6 9 0 0 9 9 9 1 Leucine Rich Repeat EF-hand_5 PF13202.6 OWF46606.1 - 9e-06 25.0 3.6 0.00078 18.8 0.2 3.0 3 0 0 3 3 3 2 EF hand LRR_4 PF12799.7 OWF46606.1 - 4.4e-05 23.8 10.9 0.0018 18.6 0.1 4.9 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF46606.1 - 0.00065 19.4 9.9 0.083 12.7 0.1 5.4 3 3 0 3 3 3 1 Leucine rich repeat EF-hand_11 PF08976.11 OWF46606.1 - 0.0072 17.2 0.1 0.016 16.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain TMIE PF16038.5 OWF46607.1 - 6.8 6.6 11.8 0.36 10.7 6.0 1.8 2 0 0 2 2 2 0 TMIE protein Methyltransf_FA PF12248.8 OWF46609.1 - 1e-19 70.7 0.2 2e-17 63.4 0.1 2.5 2 0 0 2 2 2 2 Farnesoic acid 0-methyl transferase PNP_UDP_1 PF01048.20 OWF46609.1 - 0.026 13.8 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphorylase superfamily Pribosyl_synth PF14572.6 OWF46609.1 - 0.039 14.0 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain zf-C2H2 PF00096.26 OWF46610.1 - 1e-18 66.6 27.8 7.4e-05 23.0 0.9 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF46610.1 - 6.6e-12 45.3 34.9 2.7e-06 27.5 0.5 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF46610.1 - 4.8e-09 36.3 24.0 0.0047 17.7 0.3 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 OWF46610.1 - 2.6e-05 24.7 10.4 0.067 13.8 0.0 4.2 2 2 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 OWF46610.1 - 0.1 12.6 7.3 0.12 12.4 3.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf_ZIC PF18366.1 OWF46610.1 - 0.2 11.8 5.3 0.5 10.5 0.1 3.5 2 1 1 3 3 3 0 Zic proteins zinc finger domain DUF629 PF04780.12 OWF46610.1 - 0.63 8.5 6.2 1.1 7.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF629) Zap1_zf2 PF18217.1 OWF46610.1 - 0.74 9.9 10.0 0.093 12.7 2.5 3.0 2 1 0 2 2 2 0 Zap1 zinc finger 2 zf-C2H2_2 PF12756.7 OWF46610.1 - 1.7 9.0 12.5 0.98 9.8 1.6 3.3 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 OWF46610.1 - 8 6.6 15.2 1.8 8.7 1.2 4.2 3 2 1 4 4 4 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 OWF46610.1 - 8.6 6.2 9.9 5.2 6.9 0.3 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type p450 PF00067.22 OWF46611.1 - 1.2e-115 386.9 0.3 1.4e-115 386.7 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF46612.1 - 1.3e-116 390.1 0.0 1.5e-116 389.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF46613.1 - 2.5e-92 310.1 0.0 3e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-Tim10_DDP PF02953.15 OWF46614.1 - 3.2e-14 52.3 6.7 7.4e-14 51.1 6.7 1.7 1 1 0 1 1 1 1 Tim10/DDP family zinc finger NBD94 PF16830.5 OWF46614.1 - 0.028 14.8 0.2 0.047 14.1 0.2 1.5 1 1 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH T2SSppdC PF12528.8 OWF46614.1 - 5.5 7.8 9.3 0.16 12.8 2.7 1.8 2 1 0 2 2 2 0 Type II secretion prepilin peptidase dependent protein C Arfaptin PF06456.13 OWF46615.1 - 3.4e-70 236.2 5.4 4.5e-70 235.8 5.4 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.18 OWF46615.1 - 0.0034 17.1 5.6 0.0072 16.0 5.6 1.5 1 1 0 1 1 1 1 BAR domain zf-Tim10_DDP PF02953.15 OWF46616.1 - 1.7e-24 85.2 3.1 2.1e-24 84.9 3.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3053 PF11254.8 OWF46616.1 - 0.02 14.5 0.0 1.5 8.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) dDENN PF03455.19 OWF46616.1 - 0.034 14.1 0.2 4 7.5 0.1 2.3 2 1 0 2 2 2 0 dDENN domain Kunitz_BPTI PF00014.23 OWF46617.1 - 1.3e-19 70.1 9.0 2.8e-19 69.1 9.0 1.6 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Sushi PF00084.20 OWF46617.1 - 1.1e-07 32.3 0.1 2.6e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Ufm1 PF03671.14 OWF46618.1 - 1.8e-42 143.3 0.1 2.7e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Mito_fiss_reg PF05308.11 OWF46618.1 - 2.2 8.3 5.8 2.9 7.9 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 OWF46618.1 - 5.6 6.4 8.8 7.3 6.0 8.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_S28 PF05577.12 OWF46619.1 - 1.5e-96 323.8 0.0 1.8e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OWF46619.1 - 0.00017 21.1 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 OWF46619.1 - 0.00022 20.1 0.4 0.00073 18.3 0.2 1.8 2 0 0 2 2 2 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 OWF46619.1 - 0.0026 17.1 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF46619.1 - 0.01 16.5 0.1 0.02 15.5 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF46619.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 OWF46619.1 - 0.089 11.9 0.6 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) SPC22 PF04573.12 OWF46620.1 - 3.6e-61 205.6 0.3 4e-61 205.4 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit LRR_6 PF13516.6 OWF46621.1 - 8.3e-27 90.9 24.7 0.0014 18.5 0.0 10.4 11 0 0 11 11 11 7 Leucine Rich repeat EF-hand_1 PF00036.32 OWF46621.1 - 7.3e-08 31.4 0.1 0.00072 18.9 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF46621.1 - 3.2e-07 30.7 0.5 1.3e-06 28.8 0.5 2.0 1 0 0 1 1 1 1 EF-hand domain pair LRR_1 PF00560.33 OWF46621.1 - 2.7e-06 27.1 17.1 2.5 9.0 0.0 8.8 10 1 0 10 10 10 2 Leucine Rich Repeat EF-hand_6 PF13405.6 OWF46621.1 - 3.9e-06 26.4 0.2 0.19 11.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF46621.1 - 9.4e-06 24.9 0.4 0.0006 19.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF46621.1 - 2.4e-05 24.1 0.1 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair LRR_4 PF12799.7 OWF46621.1 - 0.00015 22.1 25.3 0.029 14.8 0.3 6.9 6 1 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF46621.1 - 2.4 8.0 31.3 0.47 10.3 2.9 6.9 3 2 3 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 OWF46622.1 - 3e-20 70.5 24.0 0.00026 20.8 0.3 9.2 10 0 0 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.33 OWF46622.1 - 1.3e-07 31.2 7.3 28 5.8 0.0 8.0 7 1 0 7 7 7 0 Leucine Rich Repeat EF-hand_7 PF13499.6 OWF46622.1 - 1.4e-07 31.9 1.4 5.2e-07 30.0 0.8 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF46622.1 - 1.4e-07 31.2 0.1 1.4e-07 31.2 0.1 2.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF46622.1 - 8.3e-05 21.9 2.5 0.0026 17.2 0.1 3.3 3 0 0 3 3 3 1 EF hand LRR_8 PF13855.6 OWF46622.1 - 0.00047 19.9 14.7 0.05 13.4 0.5 6.0 2 1 4 6 6 6 5 Leucine rich repeat EF-hand_6 PF13405.6 OWF46622.1 - 0.0008 19.1 1.4 2.1 8.5 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain LRR_4 PF12799.7 OWF46622.1 - 0.0025 18.2 17.1 1 9.9 0.8 6.0 2 2 5 7 7 7 3 Leucine Rich repeats (2 copies) EF-hand_5 PF13202.6 OWF46622.1 - 0.0026 17.2 1.2 0.013 15.0 0.0 2.7 3 0 0 3 3 3 1 EF hand Methyltransf_22 PF13383.6 OWF46623.1 - 1.1e-26 93.9 2.5 9e-25 87.7 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_21 PF05050.12 OWF46623.1 - 0.00079 19.5 0.4 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase FkbM domain 7tm_1 PF00001.21 OWF46624.1 - 1.1e-24 87.2 10.2 1.6e-24 86.7 10.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.6 OWF46624.1 - 0.0075 16.2 0.0 0.035 14.0 0.0 2.0 1 1 1 2 2 2 1 TMEM154 protein family SdpI PF13630.6 OWF46624.1 - 0.027 14.6 0.1 0.027 14.6 0.1 4.0 3 1 0 3 3 3 0 SdpI/YhfL protein family DUF3328 PF11807.8 OWF46624.1 - 0.047 13.5 0.5 0.098 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF4834 PF16118.5 OWF46624.1 - 0.11 13.4 0.0 0.11 13.4 0.0 3.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4834) cNMP_binding PF00027.29 OWF46625.1 - 8.1e-21 73.9 0.1 1.3e-17 63.6 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 OWF46626.1 - 1.8e-12 47.1 0.1 2.3e-06 27.6 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain CENP-B_dimeris PF09026.10 OWF46626.1 - 0.012 16.0 0.4 0.012 16.0 0.4 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain tRNA-synt_2 PF00152.20 OWF46627.1 - 6.9e-92 307.9 0.8 9e-92 307.5 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OWF46627.1 - 0.048 13.1 0.2 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 OWF46627.1 - 0.093 12.7 0.1 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) LAMTOR PF15454.6 OWF46628.1 - 4e-19 69.0 2.6 6.2e-19 68.4 2.6 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SurA_N_2 PF13623.6 OWF46628.1 - 0.32 10.8 2.9 0.25 11.2 0.3 1.9 1 1 1 2 2 2 0 SurA N-terminal domain ShK PF01549.24 OWF46629.1 - 0.0053 17.3 8.6 0.026 15.1 8.6 2.3 1 0 0 1 1 1 1 ShK domain-like v110 PF01639.17 OWF46630.1 - 1.5 8.7 11.9 1.9 8.4 2.8 2.6 2 0 0 2 2 2 0 Viral family 110 DUF4735 PF15882.5 OWF46632.1 - 9e-75 251.8 2.2 2.3e-64 217.6 1.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4735) PMP22_Claudin PF00822.20 OWF46633.1 - 1.9e-10 40.9 14.7 2.9e-10 40.2 14.7 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family MARVEL PF01284.23 OWF46633.1 - 2.4e-07 30.9 14.0 3.2e-07 30.5 14.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Claudin_3 PF06653.11 OWF46633.1 - 4e-06 26.9 14.6 7e-06 26.1 14.6 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 OWF46633.1 - 0.00022 21.0 25.1 0.061 13.1 17.8 2.9 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction DUF2070 PF09843.9 OWF46633.1 - 0.15 10.3 4.5 0.19 10.0 4.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CD20 PF04103.15 OWF46633.1 - 0.44 10.6 14.3 1.1 9.3 10.2 2.2 2 0 0 2 2 2 0 CD20-like family DUF2231 PF09990.9 OWF46633.1 - 0.46 10.9 10.1 1.6 9.2 1.2 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF1700 PF08006.11 OWF46633.1 - 0.85 9.1 10.7 0.4 10.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Orf78 PF06024.12 OWF46633.1 - 1 9.7 2.9 7.1 7.0 0.4 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF1461 PF07314.11 OWF46633.1 - 3 7.7 8.8 1.3 8.8 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Clc-like PF07062.12 OWF46633.1 - 4.5 6.7 18.3 12 5.3 0.2 2.7 1 1 1 2 2 2 0 Clc-like DUF485 PF04341.12 OWF46633.1 - 4.6 7.3 20.0 0.42 10.6 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF485 EI24 PF07264.11 OWF46633.1 - 5 7.3 14.8 70 3.6 14.8 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF202 PF02656.15 OWF46633.1 - 6.5 7.3 19.4 22 5.6 6.9 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ank_2 PF12796.7 OWF46634.1 - 1.6e-79 262.5 9.7 2.3e-13 50.5 0.9 8.8 2 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF46634.1 - 9.3e-71 233.4 9.4 1.5e-12 47.7 0.0 13.1 7 4 8 15 15 15 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF46634.1 - 4.6e-52 173.4 14.1 4.3e-08 33.3 0.1 11.5 6 4 4 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 OWF46634.1 - 2.2e-50 167.0 20.3 9.6e-05 22.7 0.0 15.4 16 0 0 16 16 16 10 Ankyrin repeat Ank_3 PF13606.6 OWF46634.1 - 7.3e-48 155.0 10.0 0.0021 18.4 0.0 14.6 14 0 0 14 14 14 12 Ankyrin repeat CARD PF00619.21 OWF46636.1 - 3.3e-08 33.4 0.3 1.7e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 Caspase recruitment domain APG6_N PF17675.1 OWF46636.1 - 0.024 15.2 2.1 0.024 15.2 2.1 3.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 OWF46636.1 - 0.46 9.3 37.8 1.2 7.9 33.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 OWF46636.1 - 1.2 9.2 37.1 0.24 11.5 4.8 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding PikAIV_N PF18605.1 OWF46636.1 - 1.5 8.4 8.5 0.06 12.9 0.9 2.6 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HAP1_N PF04849.13 OWF46636.1 - 3 7.0 35.0 4.4 6.4 35.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region BRE1 PF08647.11 OWF46636.1 - 4.2 7.5 37.9 0.2 11.7 3.8 3.6 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 OWF46636.1 - 6.9 5.1 5.5 9.5 4.6 5.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CARD PF00619.21 OWF46637.1 - 2.8e-06 27.3 9.4 2.2e-05 24.4 0.2 3.5 3 1 0 3 3 3 2 Caspase recruitment domain GIT_CC PF16559.5 OWF46637.1 - 0.0013 18.5 4.4 0.007 16.2 4.4 2.3 1 1 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor FUSC PF04632.12 OWF46637.1 - 0.003 16.2 4.1 0.0041 15.7 4.1 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF2968 PF11180.8 OWF46637.1 - 0.01 15.5 1.1 0.01 15.5 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) CARD PF00619.21 OWF46638.1 - 1.3e-06 28.4 0.5 1.3e-06 28.4 0.5 3.0 3 0 0 3 3 3 1 Caspase recruitment domain GAS PF13851.6 OWF46638.1 - 0.00019 20.9 16.3 0.00019 20.9 16.3 3.6 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 OWF46638.1 - 0.025 15.2 9.0 0.025 15.2 9.0 3.9 1 1 2 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 OWF46638.1 - 0.19 12.0 54.2 0.073 13.3 12.6 3.9 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Ycf34 PF10718.9 OWF46638.1 - 0.31 11.7 1.6 0.96 10.2 0.0 2.4 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 Seryl_tRNA_N PF02403.22 OWF46638.1 - 2.2 8.6 40.1 0.58 10.4 16.4 4.4 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.6 OWF46638.1 - 2.3 7.9 45.2 2.9 7.5 27.3 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 OWF46638.1 - 3.6 6.6 39.5 1.2 8.2 8.0 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DHR10 PF18595.1 OWF46638.1 - 7.1 6.7 48.1 6.9 6.8 15.0 3.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain AAA PF00004.29 OWF46639.1 - 1.1e-94 313.9 0.0 4.3e-47 159.8 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF46639.1 - 3.8e-24 84.2 0.0 5.7e-11 42.1 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain Nucleolin_bd PF16725.5 OWF46639.1 - 8e-19 67.1 1.0 8e-19 67.1 1.0 2.0 2 0 0 2 2 1 1 Nucleolin binding domain AAA_2 PF07724.14 OWF46639.1 - 9.4e-14 51.9 0.0 2.3e-05 24.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OWF46639.1 - 5.1e-13 49.7 1.6 0.0012 19.3 0.0 5.3 3 2 1 5 5 5 2 AAA ATPase domain RuvB_N PF05496.12 OWF46639.1 - 1.5e-12 47.6 0.0 8.8e-05 22.3 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OWF46639.1 - 6.1e-11 42.1 1.1 9.8e-05 21.7 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OWF46639.1 - 6.2e-11 42.7 1.2 0.017 15.4 0.0 5.3 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OWF46639.1 - 4.6e-09 36.9 0.0 0.0063 17.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OWF46639.1 - 5.7e-09 36.1 0.4 0.0018 18.3 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OWF46639.1 - 4.9e-08 33.2 0.0 0.0073 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OWF46639.1 - 7e-08 32.6 0.0 0.015 15.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 OWF46639.1 - 2.1e-07 31.3 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OWF46639.1 - 4.8e-07 29.4 0.3 0.032 13.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OWF46639.1 - 5e-07 30.1 0.0 0.053 13.9 0.0 3.8 3 1 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.17 OWF46639.1 - 9.9e-07 28.6 0.1 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 OWF46639.1 - 1.3e-06 28.4 0.0 0.012 15.5 0.0 3.0 2 0 0 2 2 2 2 Rad17 P-loop domain ATPase PF06745.13 OWF46639.1 - 4.6e-06 26.2 0.2 0.049 13.0 0.0 3.6 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.6 OWF46639.1 - 4.8e-06 26.3 2.5 1.3 8.6 0.0 4.2 3 1 1 4 4 4 2 AAA domain TsaE PF02367.17 OWF46639.1 - 4.8e-06 26.6 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OWF46639.1 - 7.6e-06 26.4 0.0 0.17 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OWF46639.1 - 1.1e-05 26.0 0.0 0.4 11.2 0.0 3.2 2 0 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.18 OWF46639.1 - 1.8e-05 24.6 0.0 0.27 11.0 0.0 2.9 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 OWF46639.1 - 2.8e-05 24.3 0.0 0.055 13.6 0.0 2.8 3 0 0 3 3 2 1 Cytidylate kinase-like family Zeta_toxin PF06414.12 OWF46639.1 - 2.9e-05 23.5 0.5 0.049 12.9 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin NACHT PF05729.12 OWF46639.1 - 7.2e-05 22.8 0.6 0.37 10.7 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_3 PF07726.11 OWF46639.1 - 9.6e-05 22.3 0.0 0.37 10.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OWF46639.1 - 0.00023 21.1 0.2 0.2 11.7 0.1 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 OWF46639.1 - 0.00029 20.6 0.4 3.2 7.4 0.0 3.9 3 0 0 3 3 3 1 AAA domain SKI PF01202.22 OWF46639.1 - 0.00043 20.4 0.5 3 8.0 0.0 3.8 4 0 0 4 4 4 1 Shikimate kinase NB-ARC PF00931.22 OWF46639.1 - 0.00049 19.4 0.3 0.84 8.8 0.0 3.1 4 0 0 4 4 3 2 NB-ARC domain AAA_7 PF12775.7 OWF46639.1 - 0.00064 19.3 0.0 0.65 9.5 0.0 3.0 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 OWF46639.1 - 0.0056 16.4 0.0 2.4 7.8 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.16 OWF46639.1 - 0.0056 16.2 0.3 2 7.8 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 OWF46639.1 - 0.0076 16.2 0.1 11 5.8 0.0 3.7 2 2 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 OWF46639.1 - 0.008 15.5 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OWF46639.1 - 0.01 15.5 0.1 7.5 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 OWF46639.1 - 0.022 13.9 0.1 5.6 6.0 0.0 2.5 3 0 0 3 3 2 0 Parvovirus non-structural protein NS1 PduV-EutP PF10662.9 OWF46639.1 - 0.041 13.6 0.0 6.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 OWF46639.1 - 0.045 13.5 4.6 3.5 7.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 OWF46639.1 - 0.046 13.6 0.1 7.4 6.4 0.0 3.1 2 1 1 3 3 2 0 NTPase Sigma54_activ_2 PF14532.6 OWF46639.1 - 0.048 13.8 0.0 5.1 7.2 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 OWF46639.1 - 0.052 12.7 0.0 0.58 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 OWF46639.1 - 0.076 12.4 0.0 13 5.2 0.0 3.5 3 0 0 3 3 3 0 Bacterial TniB protein T2SSE PF00437.20 OWF46639.1 - 0.1 11.6 0.0 9.5 5.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 OWF46639.1 - 0.11 12.3 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 OWF46639.1 - 0.12 12.1 2.8 11 5.7 0.1 3.2 3 0 0 3 3 3 0 Cytidylate kinase AAA_19 PF13245.6 OWF46639.1 - 0.17 12.2 2.5 21 5.5 0.1 3.3 3 1 0 3 3 3 0 AAA domain zf-TRAF PF02176.18 OWF46640.1 - 3.2e-18 66.1 40.2 2.1e-12 47.5 6.9 4.9 2 1 3 5 5 5 4 TRAF-type zinc finger Sina PF03145.16 OWF46640.1 - 2.6e-13 50.4 24.3 2.8e-06 27.4 12.6 2.9 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF_2 PF15965.5 OWF46640.1 - 0.00031 21.1 7.3 0.00031 21.1 7.3 3.1 3 1 1 4 4 4 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 OWF46640.1 - 0.0042 16.9 5.1 0.0042 16.9 5.1 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Herpes_gp2 PF05955.11 OWF46640.1 - 0.051 13.1 1.9 0.091 12.3 1.9 1.3 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 DivIC PF04977.15 OWF46640.1 - 0.13 12.1 1.7 0.39 10.5 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 OWF46640.1 - 1 10.0 4.0 1.1 9.9 0.0 3.1 3 0 0 3 3 3 0 SlyX Yippee-Mis18 PF03226.14 OWF46640.1 - 1.9 8.7 13.5 3.2 8.0 2.4 3.2 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_5 PF14634.6 OWF46640.1 - 5.5 7.0 16.6 0.076 13.0 6.0 2.7 2 0 0 2 2 2 0 zinc-RING finger domain DUF1664 PF07889.12 OWF46640.1 - 9.3 6.3 8.1 12 6.0 3.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_C78 PF07910.13 OWF46641.1 - 7.5e-27 94.2 0.0 8.4e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C78 PF07910.13 OWF46642.1 - 2.2e-44 151.5 0.0 2.5e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 OWF46642.1 - 0.00062 19.3 3.5 0.11 11.9 1.9 2.4 1 1 2 3 3 3 2 Peptidase family C54 RCC1 PF00415.18 OWF46643.1 - 2.1e-33 114.7 10.0 3.2e-11 43.7 0.9 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OWF46643.1 - 3.1e-30 104.7 4.5 4e-16 59.2 0.0 4.5 4 1 1 5 5 5 2 BTB/POZ domain Ank_2 PF12796.7 OWF46643.1 - 3.2e-11 43.6 0.2 2.2e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF46643.1 - 1.3e-09 38.1 0.3 4.2e-05 23.7 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46643.1 - 3.6e-09 36.1 0.1 0.0046 17.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OWF46643.1 - 4.3e-08 33.6 0.4 0.0011 19.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF46643.1 - 4.9e-08 33.1 0.2 0.059 13.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat RCC1_2 PF13540.6 OWF46643.1 - 6.6e-07 29.0 25.5 2.6e-06 27.1 0.9 5.6 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DUF1388 PF07142.12 OWF46643.1 - 0.048 13.6 4.5 0.14 12.1 4.5 1.8 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Spc7 PF08317.11 OWF46644.1 - 0.00022 20.2 1.7 0.00023 20.2 1.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein HMMR_N PF15905.5 OWF46644.1 - 0.00023 20.8 1.7 0.083 12.4 0.3 1.8 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal DUF3580 PF12117.8 OWF46644.1 - 0.00032 20.9 0.7 0.036 14.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3580) KASH_CCD PF14662.6 OWF46644.1 - 0.0013 18.6 1.1 0.33 10.8 0.0 2.0 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 OWF46644.1 - 0.0016 18.0 3.4 0.002 17.6 3.4 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF641 PF04859.12 OWF46644.1 - 0.0022 18.3 1.5 0.021 15.2 0.9 1.9 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Lectin_N PF03954.14 OWF46644.1 - 0.0027 17.5 5.1 0.089 12.5 0.9 2.2 1 1 1 2 2 2 2 Hepatic lectin, N-terminal domain UPF0242 PF06785.11 OWF46644.1 - 0.0032 17.6 2.5 0.011 15.8 2.5 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 OWF46644.1 - 0.0055 17.0 5.3 0.0068 16.7 5.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 OWF46644.1 - 0.0091 16.4 2.7 15 6.1 0.2 3.8 1 1 4 5 5 5 0 Flagella accessory protein C (FlaC) RasGAP_C PF03836.15 OWF46644.1 - 0.011 15.9 7.0 0.66 10.1 0.9 2.0 1 1 1 2 2 2 0 RasGAP C-terminus BST2 PF16716.5 OWF46644.1 - 0.014 15.9 2.1 0.23 12.1 0.9 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 CSN5_C PF18323.1 OWF46644.1 - 0.017 16.0 6.8 0.42 11.6 1.5 2.7 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain TPR_MLP1_2 PF07926.12 OWF46644.1 - 0.019 15.1 1.8 0.12 12.5 1.8 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 OWF46644.1 - 0.019 15.2 1.0 0.33 11.2 0.4 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 OWF46644.1 - 0.019 14.6 2.9 0.038 13.6 2.9 1.5 1 1 0 1 1 1 0 Intermediate filament protein Sec2p PF06428.11 OWF46644.1 - 0.019 14.9 3.0 0.86 9.6 0.3 2.4 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p GLE1 PF07817.13 OWF46644.1 - 0.027 13.7 8.1 0.82 8.8 0.7 2.9 1 1 2 3 3 3 0 GLE1-like protein ATG16 PF08614.11 OWF46644.1 - 0.032 14.5 7.7 0.035 14.3 7.7 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HCMV_UL139 PF12507.8 OWF46644.1 - 0.038 14.4 0.1 9.5 6.6 0.0 2.2 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein DUF724 PF05266.14 OWF46644.1 - 0.04 13.8 1.2 0.044 13.6 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1090 PF06476.12 OWF46644.1 - 0.052 13.7 0.5 0.95 9.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) Sec8_exocyst PF04048.14 OWF46644.1 - 0.066 13.1 5.8 1.4 8.8 0.6 2.1 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF720 PF05302.11 OWF46644.1 - 0.072 12.9 6.4 0.12 12.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF720) Exonuc_VII_L PF02601.15 OWF46644.1 - 0.091 12.3 6.3 0.14 11.7 6.3 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Uds1 PF15456.6 OWF46644.1 - 0.11 12.7 4.9 0.13 12.4 4.9 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Stork_head PF10264.9 OWF46644.1 - 0.12 12.6 1.6 17 5.7 0.1 2.9 1 1 2 3 3 3 0 Winged helix Storkhead-box1 domain FliJ PF02050.16 OWF46644.1 - 0.14 12.4 0.9 0.5 10.6 0.5 1.8 1 1 1 2 2 2 0 Flagellar FliJ protein HR1 PF02185.16 OWF46644.1 - 0.17 12.0 5.3 1.6 8.9 0.3 3.1 1 1 2 3 3 3 0 Hr1 repeat LPP PF04728.13 OWF46644.1 - 0.21 12.0 3.2 4 7.9 0.2 2.6 2 2 0 2 2 2 0 Lipoprotein leucine-zipper MscS_porin PF12795.7 OWF46644.1 - 0.22 11.0 9.7 2.3 7.7 2.1 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FliD_N PF02465.18 OWF46644.1 - 0.24 12.1 5.2 2.4 8.9 0.7 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PRKG1_interact PF15898.5 OWF46644.1 - 0.31 12.0 5.3 2.4 9.1 0.2 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain zf_C2H2_ZHX PF18387.1 OWF46644.1 - 0.34 10.6 6.0 0.5 10.0 0.2 3.4 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain USP8_interact PF08941.10 OWF46644.1 - 0.41 10.4 3.6 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 USP8 interacting TMPIT PF07851.13 OWF46644.1 - 0.64 9.2 4.0 0.65 9.2 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Swi5 PF07061.11 OWF46644.1 - 0.88 9.7 4.6 17 5.6 0.3 2.9 1 1 1 2 2 2 0 Swi5 FAM76 PF16046.5 OWF46644.1 - 1 8.7 6.7 1.1 8.6 6.7 1.0 1 0 0 1 1 1 0 FAM76 protein Tiam_CC_Ex PF18385.1 OWF46649.1 - 6.9e-38 129.0 0.1 1.4e-37 128.0 0.1 1.6 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain RhoGEF PF00621.20 OWF46649.1 - 7e-38 130.7 7.6 2e-37 129.2 7.6 1.9 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 OWF46649.1 - 2e-14 53.9 1.7 1.2e-11 45.0 0.0 2.9 2 0 0 2 2 2 2 PH domain RBD PF02196.15 OWF46649.1 - 8.5e-13 48.2 0.1 4e-12 46.0 0.1 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain PH_9 PF15410.6 OWF46649.1 - 2.3e-10 40.9 0.0 5.7e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ PF00595.24 OWF46649.1 - 9.1e-05 22.7 0.0 0.00036 20.8 0.0 2.0 2 0 0 2 2 2 1 PDZ domain WH1 PF00568.23 OWF46649.1 - 0.00015 21.6 0.0 0.00086 19.2 0.0 2.3 3 0 0 3 3 3 1 WH1 domain PDZ_6 PF17820.1 OWF46649.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ank_2 PF12796.7 OWF46651.1 - 2.8e-21 75.9 5.2 3.4e-12 46.8 2.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF46651.1 - 1.8e-19 69.9 0.5 3.1e-09 37.2 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF46651.1 - 1.1e-17 63.6 3.3 1e-06 28.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OWF46651.1 - 1.8e-16 60.0 1.3 4.2e-10 39.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46651.1 - 7.2e-16 56.7 2.3 3.6e-05 23.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Chromo PF00385.24 OWF46651.1 - 1.1e-14 54.0 0.1 2.6e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3449 PF11931.8 OWF46652.1 - 5.1e-76 254.6 0.3 1.1e-75 253.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 OWF46652.1 - 1.5e-28 98.2 0.7 3.1e-28 97.2 0.7 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 OWF46652.1 - 1.6e-23 83.0 5.9 4.2e-23 81.7 5.9 1.7 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 OWF46652.1 - 7.8e-14 51.3 0.2 1.7e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 OWF46652.1 - 0.031 14.7 0.1 0.061 13.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type BLOC1S3 PF15753.5 OWF46653.1 - 2.5e-48 164.5 4.5 2.8e-48 164.3 4.5 1.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 TarH PF02203.15 OWF46653.1 - 0.027 14.4 0.1 0.027 14.4 0.1 1.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue T6PP_N PF18572.1 OWF46653.1 - 0.042 13.7 0.6 0.075 12.9 0.6 1.4 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1548 PF07579.11 OWF46653.1 - 0.063 13.6 0.1 0.09 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) DUF4389 PF14333.6 OWF46654.1 - 0.072 13.0 49.3 0.1 12.6 0.0 15.6 5 1 13 18 18 18 0 Domain of unknown function (DUF4389) MS_channel PF00924.18 OWF46654.1 - 1.3 8.5 45.3 24 4.4 0.0 14.5 4 2 14 19 19 19 0 Mechanosensitive ion channel TPR_12 PF13424.6 OWF46655.1 - 1e-28 99.5 8.1 9.9e-07 29.0 0.1 5.8 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46655.1 - 7.8e-13 47.7 0.0 0.0061 16.3 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF46655.1 - 9.3e-12 44.1 0.1 0.56 10.5 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46655.1 - 1.4e-11 43.7 0.9 0.02 15.0 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46655.1 - 5.3e-11 42.0 17.6 0.11 12.4 0.0 7.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46655.1 - 2.9e-10 39.4 0.5 0.7 10.1 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF46655.1 - 4.3e-09 36.2 0.0 0.00021 20.8 0.0 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 OWF46655.1 - 5.3e-09 36.6 0.0 0.0072 17.0 0.0 4.2 4 1 0 4 4 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 OWF46655.1 - 0.00014 21.2 0.3 0.65 9.5 0.1 3.4 2 0 0 2 2 2 2 SHNi-TPR TPR_14 PF13428.6 OWF46655.1 - 0.0012 19.5 5.2 38 5.5 0.0 7.1 6 3 3 9 9 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46655.1 - 0.016 15.7 0.8 31 5.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 OWF46655.1 - 0.048 13.4 2.8 10 5.9 0.0 4.5 5 1 0 5 5 5 0 TPR repeat TPR_6 PF13174.6 OWF46655.1 - 0.069 13.8 4.3 77 4.3 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 OWF46655.1 - 0.076 13.1 1.9 15 5.8 0.0 4.3 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain PIN_5 PF08745.11 OWF46655.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 PINc domain ribonuclease SNAP PF14938.6 OWF46655.1 - 0.12 11.8 0.0 1.5 8.2 0.0 2.5 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP NB-ARC PF00931.22 OWF46656.1 - 6e-09 35.5 0.0 8.1e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain TniB PF05621.11 OWF46656.1 - 2e-07 30.6 0.1 2.9e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 OWF46656.1 - 1.9e-06 28.2 0.1 3.3e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OWF46656.1 - 0.00037 20.5 0.6 0.0069 16.3 0.6 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OWF46656.1 - 0.00095 19.5 0.2 0.029 14.8 0.2 2.3 1 1 0 1 1 1 1 RNA helicase Cas_St_Csn2 PF16813.5 OWF46656.1 - 0.0011 18.1 0.4 0.0015 17.7 0.4 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Csn2 subfamily St AAA_14 PF13173.6 OWF46656.1 - 0.0014 18.7 1.0 0.008 16.2 1.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OWF46656.1 - 0.07 13.5 0.1 0.45 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 OWF46656.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 OWF46656.1 - 0.089 13.3 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain Peptidase_M76 PF09768.9 OWF46656.1 - 0.53 10.0 2.7 6 6.6 0.3 2.2 1 1 1 2 2 2 0 Peptidase M76 family DRMBL PF07522.14 OWF46657.1 - 5.6e-31 107.0 0.1 1.9e-30 105.3 0.1 2.0 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OWF46657.1 - 1.3e-07 31.3 0.1 2.6e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF46657.1 - 0.022 14.8 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily HECT PF00632.25 OWF46658.1 - 4e-86 289.3 0.0 6e-86 288.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OrfB_Zn_ribbon PF07282.11 OWF46658.1 - 0.012 15.5 3.5 0.033 14.1 3.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS91 PF14319.6 OWF46658.1 - 0.047 13.7 1.8 0.1 12.7 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-ribbon_3 PF13248.6 OWF46658.1 - 6.1 6.4 11.7 4.8 6.7 9.1 2.3 2 1 0 2 2 2 0 zinc-ribbon domain RrnaAD PF00398.20 OWF46659.1 - 0.042 12.9 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 7tm_1 PF00001.21 OWF46660.1 - 2.7e-77 259.7 12.5 3.4e-77 259.3 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF46660.1 - 8.3e-14 51.6 9.8 1.4e-13 50.8 9.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF46660.1 - 6.3e-08 32.7 12.1 0.00037 20.3 10.6 2.6 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF46660.1 - 5.2e-07 29.6 8.8 5.2e-07 29.6 8.8 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1385 PF07136.11 OWF46660.1 - 0.11 11.8 0.1 0.11 11.8 0.1 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1385) Git3 PF11710.8 OWF46660.1 - 3.7 7.3 13.7 16 5.2 13.7 2.0 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Fra10Ac1 PF09725.9 OWF46661.1 - 9.7e-54 180.8 2.1 2.5e-53 179.4 2.1 1.7 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 SelP_N PF04592.14 OWF46661.1 - 0.0079 15.6 3.0 0.0079 15.6 3.0 1.7 2 0 0 2 2 2 1 Selenoprotein P, N terminal region PriA_CRR PF18319.1 OWF46661.1 - 0.063 13.3 0.5 0.063 13.3 0.5 2.0 2 1 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain SNF2_N PF00176.23 OWF46662.1 - 2.1e-69 233.9 7.2 4.5e-69 232.8 5.2 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF46662.1 - 1.1e-12 48.2 0.0 3.4e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF46662.1 - 8.8e-08 32.3 0.0 2.7e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-GRF PF06839.12 OWF46662.1 - 1.1e-06 28.6 5.2 1.4e-05 25.1 0.5 2.6 2 0 0 2 2 2 1 GRF zinc finger SWI2_SNF2 PF18766.1 OWF46662.1 - 0.0056 16.4 2.2 1.2 8.8 0.0 3.5 3 0 0 3 3 3 1 SWI2/SNF2 ATPase Surfac_D-trimer PF09006.11 OWF46662.1 - 0.099 12.5 0.4 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation KLRAQ PF10205.9 OWF46662.1 - 0.21 11.8 2.6 1.1 9.5 2.6 2.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Rh5 PF18515.1 OWF46662.1 - 2.3 7.4 5.3 5.3 6.3 0.1 2.7 3 0 0 3 3 3 0 Rh5 coiled-coil domain RNase_T PF00929.24 OWF46663.1 - 6.4e-31 108.1 0.1 5e-30 105.2 0.0 2.2 2 0 0 2 2 2 1 Exonuclease SAP PF02037.27 OWF46663.1 - 0.0076 16.0 1.3 0.014 15.1 1.3 1.5 1 0 0 1 1 1 1 SAP domain Homeodomain PF00046.29 OWF46664.1 - 4.7e-21 74.4 7.2 1.1e-20 73.2 7.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF46664.1 - 0.018 14.9 0.1 0.052 13.5 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 OWF46664.1 - 0.036 13.5 0.4 0.071 12.6 0.4 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Ntox17 PF15524.6 OWF46664.1 - 0.084 13.2 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Novel toxin 17 Homeodomain PF00046.29 OWF46665.1 - 1.7e-20 72.6 7.4 3e-20 71.8 7.4 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF46665.1 - 0.002 17.5 0.1 0.0047 16.4 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF46665.1 - 0.057 13.3 0.3 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain Flu_NS2 PF00601.19 OWF46665.1 - 0.12 12.7 1.1 0.36 11.1 0.9 2.0 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) Exo_endo_phos PF03372.23 OWF46666.1 - 2.9e-15 56.4 0.0 6.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 OWF46667.1 - 8.2e-24 83.1 26.2 8.1e-10 38.3 1.7 4.4 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OWF46667.1 - 2.2e-18 66.0 30.1 1.3e-06 28.6 4.4 6.2 2 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF46667.1 - 1.8e-05 24.3 15.1 0.012 15.1 6.6 3.0 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OWF46667.1 - 0.014 15.9 20.9 0.52 11.1 1.3 7.5 6 2 1 7 7 7 0 Leucine Rich Repeat Pes-10 PF07149.11 OWF46667.1 - 0.054 12.5 21.0 0.093 11.8 21.0 1.4 1 0 0 1 1 1 0 Pes-10 RR_TM4-6 PF06459.12 OWF46667.1 - 0.067 13.0 15.6 0.099 12.4 15.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 OWF46667.1 - 0.086 13.1 4.8 0.15 12.3 4.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.12 OWF46667.1 - 0.21 9.7 31.3 0.31 9.2 31.3 1.2 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 OWF46667.1 - 0.33 11.1 3.7 0.53 10.4 3.7 1.4 1 0 0 1 1 1 0 DDHD domain Slu7 PF11708.8 OWF46667.1 - 0.4 10.4 20.0 0.61 9.8 20.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF3475 PF11961.8 OWF46667.1 - 0.56 10.3 2.7 39 4.4 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3475) Mpp10 PF04006.12 OWF46667.1 - 1.2 7.5 31.3 1.8 6.9 31.3 1.2 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 OWF46667.1 - 1.7 6.9 25.4 2.7 6.2 25.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 OWF46667.1 - 3 6.7 31.2 5 6.0 31.2 1.4 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 OWF46667.1 - 9 5.4 19.4 16 4.5 19.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4045 PF13254.6 OWF46667.1 - 9.4 5.8 12.7 13 5.3 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Xan_ur_permease PF00860.20 OWF46668.1 - 3e-72 243.5 34.0 1e-71 241.7 34.0 1.7 1 1 0 1 1 1 1 Permease family RNase_HII PF01351.18 OWF46669.1 - 3.2e-48 164.2 0.0 4e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII HNHc_6 PF16784.5 OWF46669.1 - 0.033 13.7 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease DUF4506 PF14958.6 OWF46669.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) DTC PF18102.1 OWF46670.1 - 1.5e-59 199.9 0.2 2.9e-59 199.0 0.2 1.5 1 0 0 1 1 1 1 Deltex C-terminal domain Macro PF01661.21 OWF46670.1 - 5e-34 116.9 1.2 5.3e-27 94.2 0.3 2.5 2 0 0 2 2 2 2 Macro domain zf-C3HC4_2 PF13923.6 OWF46670.1 - 3.3e-11 42.8 27.5 2e-09 37.1 11.5 3.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF46670.1 - 1.4e-09 38.1 30.2 4.3e-08 33.3 8.4 3.4 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 OWF46670.1 - 6.4e-08 32.3 25.8 2.5e-07 30.4 6.4 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF46670.1 - 2.9e-07 30.3 29.3 7.4e-05 22.6 8.7 3.6 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF46670.1 - 9.5e-07 28.7 3.3 9.5e-07 28.7 3.3 3.7 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF46670.1 - 2.7e-06 27.1 10.3 2.7e-06 27.1 10.3 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF46670.1 - 5.6e-06 26.1 22.4 1.9e-05 24.4 7.4 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OWF46670.1 - 0.002 18.3 8.9 0.002 18.3 8.9 3.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OWF46670.1 - 0.0087 16.2 16.0 0.026 14.7 4.8 3.0 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_11 PF17123.5 OWF46670.1 - 1.1 9.1 17.6 0.027 14.2 5.3 3.3 3 0 0 3 3 3 0 RING-like zinc finger Hormone_recep PF00104.30 OWF46671.1 - 0.0027 17.3 0.4 0.003 17.2 0.4 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor AsnC_trans_reg2 PF17805.1 OWF46673.1 - 0.095 12.9 0.0 0.58 10.3 0.0 1.8 1 1 1 2 2 2 0 AsnC-like ligand binding domain WD40 PF00400.32 OWF46674.1 - 2.1e-22 79.0 6.1 3.9e-06 27.5 0.2 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46674.1 - 5.2e-05 23.5 0.0 0.0063 16.8 0.0 4.4 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 OWF46674.1 - 0.052 12.8 0.1 0.3 10.3 0.0 2.1 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PIG-L PF02585.17 OWF46675.1 - 2.4e-27 96.1 0.3 7.2e-27 94.6 0.0 2.0 2 1 1 3 3 3 1 GlcNAc-PI de-N-acetylase DUF3305 PF11749.8 OWF46675.1 - 0.061 13.4 4.3 13 5.9 0.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3305) Big_6 PF17936.1 OWF46675.1 - 6.6 7.1 9.7 2.8 8.3 0.5 3.4 3 1 1 4 4 4 0 Bacterial Ig domain DUF4148 PF13663.6 OWF46676.1 - 1.4e-09 38.0 20.1 12 6.2 0.2 11.4 3 3 8 11 11 11 1 Domain of unknown function (DUF4148) DUF3305 PF11749.8 OWF46676.1 - 0.00012 22.2 17.6 8.5 6.5 0.9 7.1 1 1 8 9 9 9 4 Protein of unknown function (DUF3305) DUF1816 PF08846.10 OWF46676.1 - 0.0076 16.2 13.9 37 4.4 0.1 6.3 1 1 7 8 8 8 0 Domain of unknown function (DUF1816) Big_6 PF17936.1 OWF46676.1 - 0.013 15.7 21.4 3.6 7.9 1.1 6.0 1 1 6 7 7 7 0 Bacterial Ig domain DUF5512 PF17631.2 OWF46676.1 - 0.15 12.0 7.5 15 5.6 0.1 4.1 1 1 3 4 4 4 0 Family of unknown function (DUF5512) DUF4269 PF14091.6 OWF46676.1 - 0.28 11.4 17.1 10 6.3 0.4 5.8 1 1 5 6 6 6 0 Domain of unknown function (DUF4269) ColG_sub PF18496.1 OWF46676.1 - 0.44 10.7 27.9 3.6 7.8 0.8 5.8 1 1 4 5 5 5 0 Collagenase G catalytic helper subdomain PTS_IIA PF02255.16 OWF46676.1 - 2 8.5 22.0 34 4.6 0.1 7.3 1 1 9 10 10 10 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF5524 PF17662.1 OWF46676.1 - 2.6 7.4 20.0 4.9 6.4 5.1 3.9 1 1 1 3 3 3 0 Family of unknown function (DUF5524) DUF4367 PF14285.6 OWF46676.1 - 2.7 8.5 24.7 5.3 7.5 3.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4367) Ribosomal_S24e PF01282.19 OWF46676.1 - 3 7.8 10.1 34 4.5 0.2 4.5 1 1 3 4 4 4 0 Ribosomal protein S24e DHHA1 PF02272.19 OWF46676.1 - 6.4 7.2 11.1 16 5.9 1.5 4.0 1 1 2 3 3 3 0 DHHA1 domain PseudoU_synth_2 PF00849.22 OWF46677.1 - 5.2e-34 117.6 0.0 5.2e-34 117.6 0.0 3.6 3 1 0 3 3 3 1 RNA pseudouridylate synthase CBF PF03914.17 OWF46678.1 - 1.9e-35 122.4 0.3 2.6e-34 118.7 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 OWF46678.1 - 0.0016 17.1 1.3 0.0025 16.5 1.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Arm PF00514.23 OWF46678.1 - 0.036 14.1 0.5 0.25 11.5 0.1 2.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.23 OWF46679.1 - 3.7e-68 229.8 3.1 8.4e-68 228.6 3.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain EP400_N PF15790.5 OWF46679.1 - 2.7e-31 109.0 16.8 2.7e-31 109.0 16.8 6.5 4 4 0 4 4 4 1 E1A-binding protein p400, N-terminal HSA PF07529.13 OWF46679.1 - 2e-22 79.3 9.6 2e-22 79.3 9.6 5.0 4 1 1 5 5 5 1 HSA Helicase_C PF00271.31 OWF46679.1 - 1.9e-18 66.8 0.1 8e-18 64.8 0.1 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 OWF46679.1 - 0.0015 18.7 0.1 0.0082 16.3 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OWF46679.1 - 0.027 14.8 0.0 0.027 14.8 0.0 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF46679.1 - 0.1 12.8 2.6 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain DZR PF12773.7 OWF46680.1 - 8.9e-05 22.4 4.3 0.089 12.8 4.3 2.6 1 1 0 1 1 1 1 Double zinc ribbon D_CNTX PF17492.2 OWF46680.1 - 0.082 13.1 8.9 16 5.8 0.8 4.2 1 1 4 5 5 5 0 Delta Ctenitoxins DUF3844 PF12955.7 OWF46680.1 - 0.19 11.9 3.6 13 5.9 1.2 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3844) TB PF00683.17 OWF46680.1 - 3.5 7.4 15.5 58 3.5 0.3 4.4 1 1 4 5 5 5 0 TB domain DZR PF12773.7 OWF46681.1 - 5.5e-05 23.1 9.6 0.056 13.5 1.8 3.2 1 1 1 2 2 2 2 Double zinc ribbon DUF3844 PF12955.7 OWF46681.1 - 0.018 15.1 9.5 15 5.8 1.0 4.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3844) D_CNTX PF17492.2 OWF46681.1 - 0.052 13.7 13.4 7.6 6.8 0.4 5.1 1 1 5 6 6 6 0 Delta Ctenitoxins DZR PF12773.7 OWF46682.1 - 8.5e-08 32.1 8.7 0.005 16.8 6.6 3.1 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 OWF46682.1 - 0.27 12.0 5.9 30 5.5 0.2 3.2 1 1 1 2 2 2 0 zinc-ribbon family D_CNTX PF17492.2 OWF46682.1 - 1.5 9.1 9.5 54 4.1 0.7 4.6 1 1 5 6 6 6 0 Delta Ctenitoxins DZR PF12773.7 OWF46683.1 - 5e-09 36.0 9.4 0.044 13.8 1.0 3.8 1 1 2 3 3 3 3 Double zinc ribbon Peptidase_M10 PF00413.24 OWF46684.1 - 9.4e-52 175.0 0.0 1.3e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 OWF46684.1 - 1.9e-10 40.5 11.3 0.013 15.4 0.1 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 OWF46684.1 - 6.1e-07 29.5 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 OWF46684.1 - 0.0035 17.0 0.2 0.49 10.0 0.1 2.4 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) DUF4953 PF16313.5 OWF46684.1 - 0.016 14.5 0.5 0.024 13.8 0.5 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 OWF46684.1 - 0.058 12.3 0.3 0.098 11.6 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 OWF46684.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 OWF46684.1 - 0.19 11.6 0.4 0.4 10.6 0.4 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OWF46684.1 - 0.33 11.1 3.4 0.24 11.5 0.8 1.9 2 1 0 2 2 2 0 Metallo-peptidase family M12 Dicty_REP PF05086.12 OWF46684.1 - 0.37 8.7 4.2 0.51 8.2 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 OWF46684.1 - 2.5 8.1 36.6 0.67 9.9 33.5 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.11 OWF46684.1 - 4.8 7.6 13.8 8.7 6.8 13.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amidohydro_1 PF01979.20 OWF46685.1 - 4e-70 236.8 0.9 6.1e-70 236.2 0.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 OWF46685.1 - 2.7e-54 182.7 2.9 9e-54 181.0 2.5 2.2 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 OWF46685.1 - 3.1e-43 146.1 0.2 9.1e-43 144.6 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 OWF46685.1 - 1.7e-40 137.0 0.0 5.1e-40 135.4 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 OWF46685.1 - 2e-06 27.6 1.0 1.9e-05 24.3 0.1 2.5 2 1 0 2 2 2 1 Amidohydrolase family TSP_1 PF00090.19 OWF46687.1 - 1.9e-11 44.0 27.5 1e-07 32.1 8.2 4.7 5 0 0 5 5 5 2 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF46687.1 - 5e-05 23.8 1.3 0.00046 20.7 0.1 3.3 2 0 0 2 2 2 1 Immunoglobulin domain EGF PF00008.27 OWF46687.1 - 0.0033 17.7 6.8 0.0033 17.7 6.8 2.2 2 0 0 2 2 2 1 EGF-like domain I-set PF07679.16 OWF46687.1 - 0.012 15.7 0.2 0.052 13.6 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin I-set domain DUF5329 PF17263.2 OWF46687.1 - 6.3 7.0 6.8 1 9.6 0.9 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5329) ABC_tran PF00005.27 OWF46688.1 - 8.8e-43 146.1 0.2 3.9e-20 72.8 0.0 3.3 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OWF46688.1 - 4.5e-22 77.9 5.7 4.5e-22 77.9 5.7 1.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 OWF46688.1 - 4.2e-16 59.6 1.4 0.0013 18.6 0.0 4.8 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OWF46688.1 - 7.7e-11 41.8 0.6 0.00055 19.4 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OWF46688.1 - 6.8e-07 29.6 0.1 0.0047 17.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 OWF46688.1 - 1.9e-06 28.3 0.5 0.32 11.4 0.0 4.1 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF46688.1 - 7.3e-06 26.5 0.0 0.099 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 OWF46688.1 - 1.8e-05 24.7 0.2 0.11 12.4 0.0 2.9 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 OWF46688.1 - 2.9e-05 24.0 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF46688.1 - 3e-05 24.1 0.1 0.094 12.8 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase NB-ARC PF00931.22 OWF46688.1 - 0.00024 20.4 0.0 0.14 11.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_29 PF13555.6 OWF46688.1 - 0.00034 20.3 0.5 0.17 11.7 0.0 2.9 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 OWF46688.1 - 0.00036 20.3 0.0 0.095 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 OWF46688.1 - 0.00041 20.2 0.2 0.22 11.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 OWF46688.1 - 0.00067 19.7 0.2 0.37 10.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 OWF46688.1 - 0.0011 18.4 0.1 0.13 11.7 0.0 3.3 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_28 PF13521.6 OWF46688.1 - 0.0012 19.1 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OWF46688.1 - 0.0014 18.2 0.1 0.94 9.0 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OWF46688.1 - 0.0016 19.0 0.8 1.1 9.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 OWF46688.1 - 0.0018 18.5 0.2 0.61 10.3 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 OWF46688.1 - 0.0022 18.2 0.0 3 8.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OWF46688.1 - 0.0044 16.8 0.2 3.1 7.6 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 OWF46688.1 - 0.0059 16.3 0.1 0.95 9.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 OWF46688.1 - 0.0071 16.4 0.0 2.3 8.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 OWF46688.1 - 0.011 16.3 0.2 0.011 16.3 0.2 4.1 3 1 0 4 4 4 0 AAA domain SRP54 PF00448.22 OWF46688.1 - 0.015 14.9 0.2 6.8 6.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 OWF46688.1 - 0.016 15.1 0.2 3.2 7.6 0.1 2.9 3 0 0 3 3 3 0 NTPase SbcCD_C PF13558.6 OWF46688.1 - 0.016 15.4 0.2 4.9 7.5 0.1 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 OWF46688.1 - 0.016 14.7 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OWF46688.1 - 0.017 15.5 0.0 5.5 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 OWF46688.1 - 0.018 14.9 1.2 6.7 6.6 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Septin PF00735.18 OWF46688.1 - 0.021 14.1 0.1 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 OWF46688.1 - 0.044 13.5 19.0 0.055 13.2 0.4 4.5 2 1 2 4 4 3 0 AAA ATPase domain AAA_30 PF13604.6 OWF46688.1 - 0.048 13.4 0.1 5.5 6.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 OWF46688.1 - 0.06 12.8 0.1 0.5 9.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein dNK PF01712.19 OWF46688.1 - 0.066 13.1 0.2 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase RuvB_N PF05496.12 OWF46688.1 - 0.1 12.3 1.1 6.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF46688.1 - 0.14 12.1 0.5 10 6.1 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 OWF46688.1 - 0.35 8.3 9.2 0.98 6.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 OWF46688.1 - 0.92 8.1 7.5 4.2 5.9 0.1 2.9 2 2 1 3 3 3 0 AAA domain DUF87 PF01935.17 OWF46688.1 - 1.4 9.0 6.2 2.5 8.1 0.0 3.4 4 0 0 4 4 3 0 Helicase HerA, central domain DLIC PF05783.11 OWF46688.1 - 1.7 7.4 5.6 5.6 5.7 0.0 3.2 3 1 1 4 4 4 0 Dynein light intermediate chain (DLIC) ORF6C PF10552.9 OWF46689.1 - 0.98 9.5 10.2 0.27 11.3 1.5 2.4 2 0 0 2 2 2 0 ORF6C domain DHR10 PF18595.1 OWF46689.1 - 2.2 8.4 10.5 11 6.1 9.9 2.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain SUZ PF12752.7 OWF46690.1 - 1e-14 55.0 0.3 1e-14 55.0 0.3 2.3 2 1 0 2 2 2 1 SUZ domain SUZ-C PF12901.7 OWF46690.1 - 0.00068 19.6 4.4 0.0014 18.6 4.4 1.6 1 0 0 1 1 1 1 SUZ-C motif T-box PF00907.22 OWF46690.1 - 0.094 13.0 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 T-box UDPGT PF00201.18 OWF46691.1 - 2.6e-79 267.3 0.1 3.2e-79 267.0 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 OWF46692.1 - 2.1e-81 274.3 0.1 2.5e-81 274.0 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OWF46692.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 OWF46693.1 - 3.9e-78 263.4 0.0 4.7e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OWF46693.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Arm PF00514.23 OWF46694.1 - 2.4 8.3 4.7 8.8 6.5 0.1 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat tRNA_synthFbeta PF17759.1 OWF46695.1 - 4.7e-51 173.3 0.0 7.8e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OWF46695.1 - 2.4e-29 101.3 0.3 1.6e-28 98.7 0.2 2.3 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OWF46695.1 - 5.4e-27 94.6 0.0 1e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OWF46695.1 - 8.4e-17 61.2 0.0 3.7e-14 52.8 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetase B5 domain Kinesin PF00225.23 OWF46696.1 - 5.3e-100 334.6 2.8 5.3e-100 334.6 2.8 4.4 5 0 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 OWF46696.1 - 2.8e-17 63.1 5.1 2.5e-15 56.7 0.1 4.5 3 0 0 3 3 3 2 Microtubule binding ANAPC5 PF12862.7 OWF46696.1 - 0.039 14.0 3.8 0.13 12.4 0.2 3.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 RNase_T PF00929.24 OWF46697.1 - 4.8e-06 27.2 0.1 7.8e-05 23.3 0.1 2.8 1 1 0 1 1 1 1 Exonuclease DNA_pol_B_exo1 PF03104.19 OWF46697.1 - 8.8e-06 25.1 0.1 1.4e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF5051 PF16473.5 OWF46697.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_B_exo2 PF10108.9 OWF46697.1 - 0.0033 17.1 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB S6OS1 PF15676.5 OWF46698.1 - 8.6e-17 60.8 13.0 1.2e-16 60.4 13.0 1.3 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family SKA2 PF16740.5 OWF46698.1 - 0.0049 16.6 6.8 0.0049 16.6 6.8 2.6 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 2 RMMBL PF07521.12 OWF46698.1 - 0.026 14.4 1.4 0.044 13.7 0.2 2.2 2 0 0 2 2 1 0 Zn-dependent metallo-hydrolase RNA specificity domain DUF948 PF06103.11 OWF46698.1 - 0.026 14.8 1.4 0.026 14.8 1.4 2.7 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RasGAP_C PF03836.15 OWF46698.1 - 0.032 14.4 1.9 0.032 14.4 1.9 3.5 1 1 1 3 3 3 0 RasGAP C-terminus CLZ PF16526.5 OWF46698.1 - 0.041 14.2 8.3 0.12 12.8 0.6 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Csm1_N PF18504.1 OWF46698.1 - 0.065 13.6 1.2 0.065 13.6 1.2 3.9 4 0 0 4 4 3 0 Csm1 N-terminal domain Nup54_57_C PF18570.1 OWF46698.1 - 0.076 12.6 0.9 0.22 11.2 0.3 2.1 2 0 0 2 2 1 0 NUP57/Nup54 C-terminal domain Phage_tail_NK PF16532.5 OWF46698.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales NPV_P10 PF05531.12 OWF46698.1 - 0.1 13.1 0.5 0.1 13.1 0.5 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 OWF46698.1 - 0.11 13.0 26.9 0.12 12.9 3.1 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc29 PF17082.5 OWF46698.1 - 0.22 11.3 14.8 0.39 10.5 2.5 2.9 1 1 1 2 2 2 0 Spindle Pole Component 29 BLOC1_2 PF10046.9 OWF46698.1 - 0.23 11.8 18.6 0.59 10.5 2.8 3.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PI3K_P85_iSH2 PF16454.5 OWF46698.1 - 0.5 9.9 28.9 1 9.0 2.9 4.1 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CdiA_C PF18451.1 OWF46698.1 - 0.63 10.3 4.0 3.9 7.7 0.5 2.5 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Atg14 PF10186.9 OWF46698.1 - 0.64 9.1 27.8 0.84 8.7 6.4 3.8 2 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4988 PF16378.5 OWF46698.1 - 0.77 9.4 7.7 0.11 12.2 0.8 2.8 3 1 0 3 3 3 0 Domain of unknown function Tropomyosin_1 PF12718.7 OWF46698.1 - 0.79 9.9 29.4 0.13 12.4 4.4 3.0 2 1 1 3 3 3 0 Tropomyosin like Enkurin PF13864.6 OWF46698.1 - 0.84 10.1 19.7 0.07 13.6 10.7 3.2 2 1 0 2 2 2 0 Calmodulin-binding Peptidase_S46 PF10459.9 OWF46698.1 - 1.4 7.5 10.0 1.5 7.4 9.2 1.3 1 1 0 1 1 1 0 Peptidase S46 DUF4407 PF14362.6 OWF46698.1 - 1.7 7.9 18.1 0.065 12.6 10.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LPP PF04728.13 OWF46698.1 - 3.2 8.2 7.6 3.5 8.1 0.7 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper GrpE PF01025.19 OWF46698.1 - 3.3 7.3 15.3 9.8e+02 -0.7 14.9 2.8 1 1 0 1 1 1 0 GrpE ABC_tran_CTD PF16326.5 OWF46698.1 - 4.1 7.7 14.0 0.15 12.4 0.6 3.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain Spore_III_AB PF09548.10 OWF46698.1 - 4.5 7.4 13.7 0.23 11.5 1.0 3.1 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Occludin_ELL PF07303.13 OWF46698.1 - 4.8 8.0 18.3 11 6.8 1.3 3.9 1 1 3 4 4 4 0 Occludin homology domain Spc7 PF08317.11 OWF46698.1 - 5.7 5.7 30.0 1.7 7.4 13.2 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF2730 PF10805.8 OWF46698.1 - 6 7.0 8.5 1 9.5 1.7 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) Lebercilin PF15619.6 OWF46698.1 - 6.2 6.4 29.6 2.3 7.9 19.9 3.0 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 OWF46698.1 - 6.5 6.9 20.8 18 5.5 5.5 3.1 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF812 PF05667.11 OWF46698.1 - 6.9 5.4 27.3 2.3 7.0 16.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF724 PF05266.14 OWF46698.1 - 7.9 6.3 23.8 0.48 10.2 4.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) THOC7 PF05615.13 OWF46698.1 - 9 6.6 21.8 0.43 10.8 9.6 2.6 1 1 1 2 2 1 0 Tho complex subunit 7 CTD PF12815.7 OWF46699.1 - 0.028 15.0 5.1 0.32 11.6 2.2 3.8 2 1 1 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 BAR_3 PF16746.5 OWF46700.1 - 9.4e-77 257.9 10.2 2e-76 256.8 10.2 1.6 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 OWF46700.1 - 5.6e-40 136.1 0.5 1.8e-39 134.4 0.5 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 OWF46700.1 - 2.7e-21 75.9 1.0 2.1e-12 47.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 OWF46700.1 - 2.4e-14 53.7 0.6 2.4e-14 53.7 0.6 2.5 3 0 0 3 3 2 1 PH domain Ank_3 PF13606.6 OWF46700.1 - 5.3e-11 41.8 0.2 0.0024 18.2 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OWF46700.1 - 6.2e-11 42.3 0.3 3.8e-06 27.1 0.0 3.4 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF46700.1 - 1.3e-10 41.6 0.0 0.0057 17.2 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF46700.1 - 4.1e-09 36.5 0.4 0.00043 20.6 0.1 3.8 4 0 0 4 4 3 2 Ankyrin repeat BAR PF03114.18 OWF46700.1 - 0.0026 17.4 2.5 0.0056 16.4 2.5 1.5 1 0 0 1 1 1 1 BAR domain Csm2_III-A PF03750.13 OWF46700.1 - 0.063 14.1 0.2 0.25 12.2 0.2 2.1 1 0 0 1 1 1 0 Csm2 Type III-A PH_8 PF15409.6 OWF46700.1 - 0.066 13.5 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 OWF46700.1 - 0.89 10.0 11.4 0.24 11.8 4.0 3.7 3 1 0 3 3 3 0 Pleckstrin homology domain Bac_RepA_C PF18008.1 OWF46700.1 - 1.4 9.3 4.5 17 5.9 0.2 3.0 3 0 0 3 3 3 0 Replication initiator protein A C-terminal domain Cytochrom_B562 PF07361.11 OWF46700.1 - 7.5 7.3 9.1 0.27 11.9 0.6 2.8 3 0 0 3 3 2 0 Cytochrome b562 RP-C_C PF11800.8 OWF46700.1 - 7.9 6.5 7.9 0.39 10.8 0.1 2.6 3 0 0 3 3 3 0 Replication protein C C-terminal region Enolase_C PF00113.22 OWF46701.1 - 9.3e-154 511.0 0.2 1.4e-153 510.3 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OWF46701.1 - 1.2e-58 197.0 0.1 2.4e-58 196.0 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OWF46701.1 - 4.3e-07 29.7 0.0 1.2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OWF46701.1 - 0.0001 21.6 0.1 0.00018 20.7 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus TamB PF04357.13 OWF46701.1 - 0.053 12.8 0.1 0.084 12.1 0.1 1.2 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex DUF2528 PF10800.8 OWF46701.1 - 0.094 13.3 0.2 0.7 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) Enolase_C PF00113.22 OWF46702.1 - 2.8e-36 125.3 0.0 3.2e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain C5-epim_C PF06662.13 OWF46703.1 - 1.2e-72 243.3 0.3 1.9e-72 242.7 0.3 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Pec_lyase PF09492.10 OWF46703.1 - 0.099 12.0 0.2 9 5.5 0.1 2.2 2 0 0 2 2 2 0 Pectic acid lyase E1-E2_ATPase PF00122.20 OWF46704.1 - 8.5e-35 119.9 2.3 1e-34 119.7 0.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 OWF46704.1 - 1.2e-23 83.6 0.1 4.1e-23 81.8 0.1 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 OWF46704.1 - 1.4e-18 67.9 0.0 6.6e-10 39.6 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OWF46704.1 - 2.9e-07 30.1 0.0 2.9e-07 30.1 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OWF46704.1 - 5.2e-06 26.5 0.0 1.7e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 OWF46704.1 - 0.0057 16.4 7.5 0.0057 16.4 7.5 3.3 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 OWF46704.1 - 0.023 14.4 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DFF40 PF09230.10 OWF46705.1 - 5.3e-72 242.1 1.8 7.2e-72 241.7 1.8 1.2 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa CIDE-N PF02017.15 OWF46705.1 - 1.1e-29 102.3 0.6 1.1e-29 102.3 0.6 1.8 2 0 0 2 2 2 1 CIDE-N domain Jag_N PF14804.6 OWF46705.1 - 0.0035 17.6 0.4 0.0089 16.3 0.3 1.8 2 0 0 2 2 2 1 Jag N-terminus CLASP_N PF12348.8 OWF46706.1 - 0.0013 18.3 0.1 0.0062 16.1 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal UVR PF02151.19 OWF46706.1 - 0.006 16.3 20.8 0.028 14.2 4.2 3.2 3 0 0 3 3 3 2 UvrB/uvrC motif zf_UBZ PF18439.1 OWF46706.1 - 0.007 15.9 6.5 0.21 11.2 0.5 3.2 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger AAA_23 PF13476.6 OWF46706.1 - 0.33 11.4 7.8 0.27 11.7 0.9 2.3 2 0 0 2 2 2 0 AAA domain Sgf11 PF08209.11 OWF46706.1 - 0.45 10.1 3.3 2.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Com_YlbF PF06133.11 OWF46706.1 - 6.3 7.5 16.8 3.2 8.4 4.8 2.8 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA RICTOR_N PF14664.6 OWF46707.1 - 0.008 15.2 0.6 0.015 14.3 0.6 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term V-ATPase_H_N PF03224.14 OWF46707.1 - 0.023 14.0 0.1 0.051 12.9 0.1 1.6 1 0 0 1 1 1 0 V-ATPase subunit H FAST_2 PF08368.12 OWF46708.1 - 0.0017 19.1 0.1 0.0063 17.3 0.0 2.1 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 RAP PF08373.10 OWF46708.1 - 0.011 15.9 0.2 0.037 14.1 0.2 1.9 1 0 0 1 1 1 0 RAP domain KOG2701 PF09762.9 OWF46708.1 - 0.061 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) WAP PF00095.21 OWF46709.1 - 3.2e-05 24.2 13.2 3.2e-05 24.2 13.2 2.6 3 1 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Peptidase_M13_N PF05649.13 OWF46711.1 - 3e-110 369.5 1.3 4.2e-110 369.0 1.3 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF46711.1 - 9.7e-74 247.4 0.0 1.9e-73 246.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 7TM_GPCR_Srw PF10324.9 OWF46712.1 - 1.6e-28 99.9 21.3 1.9e-27 96.4 21.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF46712.1 - 4.5e-16 59.0 17.0 8.3e-16 58.1 17.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 OWF46712.1 - 0.0044 16.2 18.9 0.0063 15.7 18.9 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) RhoGAP-FF1 PF16512.5 OWF46712.1 - 0.07 13.8 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain DUF2723 PF11028.8 OWF46712.1 - 0.076 12.9 9.1 0.78 9.6 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2723) DUF1129 PF06570.11 OWF46712.1 - 4.1 6.8 11.3 3 7.3 3.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Glyco_hydro_9 PF00759.19 OWF46713.1 - 2e-133 445.8 13.4 2.6e-133 445.4 13.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 OWF46713.1 - 1.9e-07 31.3 2.1 5.8e-07 29.8 2.1 1.8 1 0 0 1 1 1 1 Cellulose binding domain Big_3_5 PF16640.5 OWF46713.1 - 0.7 10.1 8.3 1.8 8.8 5.6 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Aminotran_5 PF00266.19 OWF46714.1 - 1.5e-47 162.3 0.0 1.8e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Glyco_transf_11 PF01531.16 OWF46715.1 - 2.8e-13 49.8 0.5 3e-13 49.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Rootletin PF15035.6 OWF46716.1 - 1.4e-64 217.6 24.1 1.4e-64 217.6 24.1 14.5 5 3 7 13 13 13 1 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 OWF46716.1 - 0.005 17.0 19.1 0.005 17.0 19.1 17.4 4 3 12 16 16 16 3 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OWF46716.1 - 0.0085 16.6 4.1 0.0085 16.6 4.1 20.8 5 4 16 21 21 21 7 Apg6 coiled-coil region Pex2_Pex12 PF04757.14 OWF46717.1 - 1.3e-25 90.3 0.4 1.7e-25 89.9 0.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Phage_lysozyme PF00959.19 OWF46717.1 - 0.037 14.5 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 Phage lysozyme HORMA PF02301.18 OWF46718.1 - 3.7e-08 33.2 0.1 2.6e-07 30.4 0.1 2.0 1 1 0 1 1 1 1 HORMA domain DUF3287 PF11690.8 OWF46720.1 - 0.0054 16.5 1.7 0.019 14.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3287) PRANC PF09372.10 OWF46720.1 - 0.029 14.7 0.4 0.11 12.8 0.3 2.1 1 1 0 1 1 1 0 PRANC domain DUF2023 PF09633.10 OWF46720.1 - 0.085 13.0 0.6 0.21 11.7 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) DUF4800 PF16057.5 OWF46720.1 - 0.13 11.5 2.5 0.33 10.2 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4800) CENP-Q PF13094.6 OWF46720.1 - 0.43 10.8 8.0 0.074 13.2 0.7 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.11 OWF46720.1 - 9.2 6.7 11.6 22 5.5 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MIB_HERC2 PF06701.13 OWF46721.1 - 1.9e-50 169.0 23.2 7.4e-26 90.2 4.0 4.1 4 0 0 4 4 4 2 Mib_herc2 Ank_2 PF12796.7 OWF46721.1 - 2.4e-46 156.2 31.9 5.9e-13 49.2 1.3 5.9 1 1 7 8 8 8 6 Ankyrin repeats (3 copies) SH3_15 PF18346.1 OWF46721.1 - 5.8e-42 141.9 10.5 1.6e-21 76.4 0.3 3.8 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank PF00023.30 OWF46721.1 - 6.9e-34 114.8 15.2 1.8e-05 24.9 0.2 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 OWF46721.1 - 8.6e-34 115.5 8.4 4.6e-08 33.5 0.2 7.2 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF46721.1 - 8.9e-29 99.2 10.7 9.6e-07 29.0 1.0 7.5 2 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46721.1 - 2.1e-22 76.8 6.0 0.011 16.2 0.0 9.3 9 0 0 9 9 9 5 Ankyrin repeat zf-C3HC4_3 PF13920.6 OWF46721.1 - 1.4e-12 47.2 44.7 1.3e-07 31.3 10.7 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 OWF46721.1 - 4.3e-11 42.4 6.5 4.3e-11 42.4 6.5 3.9 4 1 0 4 4 4 1 Zinc finger, ZZ type Sun2_CC2 PF18580.1 OWF46721.1 - 0.04 14.1 0.0 2.9 8.2 0.1 2.8 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Dishevelled PF02377.15 OWF46722.1 - 2.3e-53 180.9 27.4 2.3e-53 180.9 27.4 2.1 3 0 0 3 3 3 1 Dishevelled specific domain DIX PF00778.17 OWF46722.1 - 6.1e-32 109.3 0.2 1.3e-31 108.3 0.2 1.6 1 0 0 1 1 1 1 DIX domain PDZ PF00595.24 OWF46722.1 - 1.1e-20 73.7 0.8 1.9e-20 73.0 0.8 1.4 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 OWF46722.1 - 9.5e-17 60.8 0.0 2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 OWF46722.1 - 9.9e-08 31.7 0.1 1.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF46722.1 - 0.00032 20.9 0.2 0.00069 19.9 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Alk_phosphatase PF00245.20 OWF46723.1 - 1.3e-144 482.2 2.6 1.5e-144 482.0 2.6 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF46723.1 - 0.022 14.1 0.6 0.04 13.3 0.1 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily Sulfatase PF00884.23 OWF46723.1 - 0.19 11.1 2.7 5.7 6.2 2.6 2.8 1 1 0 1 1 1 0 Sulfatase PAX PF00292.18 OWF46724.1 - 3.1e-58 195.1 0.9 6.6e-58 194.1 0.9 1.6 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 OWF46724.1 - 3.1e-07 30.0 0.0 6.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 OWF46724.1 - 0.00043 20.8 0.2 0.022 15.3 0.0 2.8 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 OWF46724.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 OWF46724.1 - 0.0017 18.4 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 OWF46724.1 - 0.028 14.2 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PhyH PF05721.13 OWF46725.1 - 0.00045 20.5 0.1 0.0026 18.0 0.1 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3721 PF12518.8 OWF46726.1 - 0.0015 18.3 23.1 17 5.4 0.1 11.6 7 4 8 15 15 15 2 Protein of unknown function DUF3089 PF11288.8 OWF46726.1 - 0.035 13.6 2.5 45 3.5 0.0 5.0 2 1 3 5 5 5 0 Protein of unknown function (DUF3089) NIR_SIR PF01077.22 OWF46726.1 - 0.096 12.2 0.1 27 4.2 0.1 5.2 2 1 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain LSR PF05624.14 OWF46726.1 - 0.3 11.1 3.2 0.74 9.9 3.2 1.7 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Y_phosphatase PF00102.27 OWF46727.1 - 8.7e-74 248.0 0.2 1.5e-73 247.2 0.2 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 OWF46727.1 - 9.2e-49 163.5 0.8 6.2e-23 80.7 0.1 2.8 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.20 OWF46727.1 - 0.00012 21.9 0.2 0.00034 20.4 0.2 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF46727.1 - 0.0004 20.5 0.0 0.0015 18.7 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF46727.1 - 0.036 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family p450 PF00067.22 OWF46728.1 - 1.3e-238 792.3 0.0 5.7e-119 397.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Flp_N PF03930.14 OWF46728.1 - 0.033 14.1 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus DUF1699 PF08004.11 OWF46728.1 - 0.16 11.7 0.0 9.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) DUF4916 PF16262.5 OWF46728.1 - 0.17 11.4 0.0 16 5.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4916) Tma16 PF11176.8 OWF46728.1 - 4.5 7.1 4.9 24 4.8 0.5 2.3 2 0 0 2 2 2 0 Translation machinery-associated protein 16 p450 PF00067.22 OWF46729.1 - 6.9e-96 321.8 0.1 7.7e-96 321.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 ANF_receptor PF01094.28 OWF46730.1 - 2.7e-77 260.3 0.0 3.6e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 OWF46730.1 - 9.6e-61 205.5 18.3 2e-60 204.5 18.3 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 OWF46730.1 - 1.7e-09 37.5 9.5 4e-09 36.3 9.5 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Amino_oxidase PF01593.24 OWF46731.1 - 5.4e-08 32.6 0.0 8.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF46731.1 - 0.00019 21.6 0.1 0.00051 20.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OWF46731.1 - 0.015 14.6 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mucin PF01456.17 OWF46731.1 - 0.71 9.9 22.9 1.4 8.9 22.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Amino_oxidase PF01593.24 OWF46732.1 - 1.1e-11 44.7 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF46732.1 - 1.4e-09 38.0 0.0 3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OWF46732.1 - 3.4e-07 29.8 0.8 1.1e-06 28.2 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF46732.1 - 1.8e-05 24.1 0.0 9.5e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF46732.1 - 5.6e-05 22.4 0.1 8.3e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OWF46732.1 - 6.6e-05 22.6 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OWF46732.1 - 0.00014 20.7 0.4 0.00014 20.7 0.4 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OWF46732.1 - 0.0004 19.7 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OWF46732.1 - 0.00042 20.8 0.3 0.019 15.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF46732.1 - 0.0033 16.8 0.0 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OWF46732.1 - 0.0081 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A IlvN PF07991.12 OWF46732.1 - 0.04 13.5 0.0 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Chorion_2 PF03964.15 OWF46732.1 - 0.043 14.7 7.3 0.12 13.2 7.3 1.7 1 0 0 1 1 1 0 Chorion family 2 Lycopene_cycl PF05834.12 OWF46732.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 OWF46732.1 - 0.045 13.2 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Macoilin PF09726.9 OWF46732.1 - 0.087 11.4 2.5 0.12 11.0 2.5 1.1 1 0 0 1 1 1 0 Macoilin family Thi4 PF01946.17 OWF46732.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 OWF46732.1 - 0.19 11.7 0.0 0.52 10.3 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 OWF46732.1 - 0.2 12.3 0.1 0.4 11.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OWF46732.1 - 0.21 11.9 0.1 0.39 11.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_21 PF05050.12 OWF46734.1 - 0.0006 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain p450 PF00067.22 OWF46735.1 - 1.3e-115 386.8 0.0 1.6e-115 386.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ICAT PF06384.11 OWF46736.1 - 1.1e-32 112.0 0.4 1.1e-32 112.0 0.4 1.8 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.11 OWF46736.1 - 4.9e-05 23.0 0.9 9.4e-05 22.1 0.9 1.5 1 0 0 1 1 1 1 CAMP factor (Cfa) TetR_C_6 PF13977.6 OWF46736.1 - 0.0038 17.4 0.2 0.097 12.9 0.0 2.1 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal DUF2357 PF09823.9 OWF46736.1 - 0.0056 16.0 2.9 0.057 12.7 1.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF2357) T2SSF PF00482.23 OWF46736.1 - 0.016 15.1 2.6 0.31 11.0 0.0 2.5 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F AAA_18 PF13238.6 OWF46736.1 - 0.029 14.9 0.5 0.043 14.4 0.5 1.3 1 0 0 1 1 1 0 AAA domain TetR_C_11 PF16859.5 OWF46736.1 - 0.051 13.9 0.1 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 OWF46736.1 - 0.056 13.5 0.2 0.16 12.0 0.0 1.9 1 1 1 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain GvpG PF05120.12 OWF46736.1 - 0.072 13.1 8.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Gas vesicle protein G CK2S PF15011.6 OWF46736.1 - 0.08 12.8 6.9 2 8.3 1.0 2.9 2 1 1 3 3 3 0 Casein Kinase 2 substrate PRESAN PF09687.10 OWF46736.1 - 0.14 12.7 3.0 0.3 11.7 2.9 1.6 2 0 0 2 2 2 0 Plasmodium RESA N-terminal TMCO5 PF14992.6 OWF46736.1 - 0.2 11.2 12.0 0.17 11.4 9.4 1.8 1 1 1 2 2 2 0 TMCO5 family MnmE_helical PF12631.7 OWF46736.1 - 0.48 10.6 7.4 2.6 8.2 7.4 2.0 1 1 0 1 1 1 0 MnmE helical domain DUF2408 PF10303.9 OWF46736.1 - 0.64 10.6 9.5 0.46 11.1 7.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF883 PF05957.13 OWF46736.1 - 0.71 10.5 5.7 0.8 10.3 1.1 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FapA PF03961.13 OWF46736.1 - 0.79 8.2 9.6 0.62 8.6 7.0 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A YabA PF06156.13 OWF46736.1 - 1.7 9.3 7.9 2.3 8.9 2.0 2.7 1 1 1 2 2 2 0 Initiation control protein YabA YtxH PF12732.7 OWF46736.1 - 4.3 7.9 6.7 3.7 8.2 2.0 2.6 2 2 0 2 2 2 0 YtxH-like protein FlxA PF14282.6 OWF46736.1 - 4.7 7.3 12.5 0.4 10.7 4.7 2.9 2 2 2 4 4 4 0 FlxA-like protein CLZ PF16526.5 OWF46736.1 - 6.6 7.2 12.4 0.38 11.1 1.5 2.9 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Polysacc_deac_1 PF01522.21 OWF46737.1 - 2.7e-06 27.3 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Adaptin_binding PF10199.9 OWF46738.1 - 1.8 9.2 6.3 1.4 9.5 5.0 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RCR PF12273.8 OWF46742.1 - 0.068 13.8 0.1 0.12 13.0 0.1 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red OppC_N PF12911.7 OWF46742.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Amino_oxidase PF01593.24 OWF46743.1 - 1e-17 64.6 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF46743.1 - 2.7e-12 46.8 0.0 7.3e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OWF46743.1 - 4.3e-08 32.8 0.0 6.1e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF46743.1 - 1.3e-05 24.9 0.0 6.3e-05 22.7 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF46743.1 - 0.00031 20.1 0.1 0.00055 19.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OWF46743.1 - 0.001 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF46743.1 - 0.0011 19.5 0.1 0.041 14.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF46743.1 - 0.0017 17.1 0.5 0.0028 16.4 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OWF46743.1 - 0.0022 17.2 0.2 0.0033 16.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OWF46743.1 - 0.0035 16.6 0.1 0.0054 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OWF46743.1 - 0.019 14.1 0.1 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OWF46743.1 - 0.037 13.4 0.0 0.16 11.2 0.0 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF3137 PF11335.8 OWF46743.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3137) GIDA PF01134.22 OWF46743.1 - 0.15 11.2 0.1 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lipase_GDSL_2 PF13472.6 OWF46744.1 - 1.6e-05 25.4 0.0 1.8e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF46744.1 - 0.033 14.1 0.0 0.043 13.8 0.0 1.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase API5 PF05918.11 OWF46745.1 - 9.9e-202 671.3 0.1 1.2e-201 671.0 0.1 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 OWF46745.1 - 0.00071 19.9 0.0 0.041 14.3 0.1 2.5 1 1 1 2 2 2 1 HEAT repeats MMS19_N PF14500.6 OWF46745.1 - 0.015 14.9 0.2 0.049 13.2 0.2 2.1 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II SNURF PF07192.11 OWF46745.1 - 0.06 13.2 0.3 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 SNURF/RPN4 protein RIX1 PF08167.12 OWF46745.1 - 0.11 12.3 0.5 1.7 8.4 0.1 2.6 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 OWF46745.1 - 0.58 10.2 4.2 35 4.4 3.9 3.2 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1619 PF07773.11 OWF46746.1 - 5e-65 220.5 14.6 5.2e-64 217.2 12.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1619) Me-amine-dh_L PF02975.14 OWF46746.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.7 2 0 0 2 2 2 0 Methylamine dehydrogenase, L chain MFS_1 PF07690.16 OWF46748.1 - 2e-33 115.8 46.7 4.9e-31 107.9 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF46748.1 - 1e-32 113.6 18.5 1.3e-32 113.3 18.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter BPL_N PF09825.9 OWF46749.1 - 2.5e-59 201.3 7.8 4e-45 154.5 5.2 2.3 1 1 2 3 3 3 2 Biotin-protein ligase, N terminal GATase_3 PF07685.14 OWF46749.1 - 0.00086 19.0 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 OWF46749.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 Peptidase family S51 Kinesin PF00225.23 OWF46750.1 - 1.7e-110 369.1 0.0 3.4e-110 368.1 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF46750.1 - 9.6e-23 80.8 1.9 1.8e-22 79.9 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding CEP209_CC5 PF16574.5 OWF46750.1 - 0.19 11.9 4.3 0.62 10.2 4.3 1.9 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DUF4570 PF15134.6 OWF46750.1 - 3.1 7.8 6.3 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) WD40 PF00400.32 OWF46751.1 - 4.5e-07 30.5 8.9 0.024 15.5 0.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Tetraspanin PF00335.20 OWF46752.1 - 9.1e-34 117.1 11.6 1.1e-33 116.8 11.6 1.1 1 0 0 1 1 1 1 Tetraspanin family SIT PF15330.6 OWF46752.1 - 0.06 13.8 0.4 5.5 7.5 0.3 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT CitMHS PF03600.16 OWF46752.1 - 0.07 12.3 7.6 0.37 10.0 4.1 2.2 2 0 0 2 2 2 0 Citrate transporter DUF4381 PF14316.6 OWF46752.1 - 0.51 10.6 1.5 51 4.1 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4381) Glycophorin_A PF01102.18 OWF46752.1 - 1.8 8.8 3.2 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A SCIMP PF15050.6 OWF46752.1 - 4.1 7.9 4.6 0.98 9.9 0.2 2.1 2 0 0 2 2 2 0 SCIMP protein Methyltransf_5 PF01795.19 OWF46753.1 - 7.9e-81 271.9 0.1 9.9e-81 271.6 0.1 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 OWF46753.1 - 0.00041 21.0 0.0 0.0011 19.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF46753.1 - 0.0023 17.7 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OWF46753.1 - 0.0082 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_19 PF04672.12 OWF46753.1 - 0.017 14.6 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_15 PF09445.10 OWF46753.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 OWF46753.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 OWF46753.1 - 0.044 14.5 0.0 0.27 12.0 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Sulfotransfer_3 PF13469.6 OWF46753.1 - 0.048 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Methyltransf_24 PF13578.6 OWF46753.1 - 0.075 14.1 0.0 1.5 9.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 OWF46753.1 - 0.13 12.9 0.0 0.34 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain COPIIcoated_ERV PF07970.12 OWF46754.1 - 1.5e-45 155.8 0.1 2.3e-45 155.1 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OWF46754.1 - 1.8e-27 95.5 0.1 3.9e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NDT80_PhoG PF05224.12 OWF46755.1 - 5.1e-27 95.3 0.6 5.7e-26 91.9 0.6 2.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 OWF46755.1 - 2e-21 74.9 2.2 3.8e-21 74.0 2.2 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 MRF_C2 PF13888.6 OWF46755.1 - 5.6e-15 55.4 3.0 1.6e-14 54.0 3.0 1.8 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 Peptidase_S74 PF13884.6 OWF46755.1 - 3.4e-12 46.5 0.2 7.9e-12 45.3 0.2 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase PrgH PF09480.10 OWF46755.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) CarboxypepD_reg PF13620.6 OWF46756.1 - 1.4e-45 153.5 20.8 1e-08 35.3 1.6 10.3 10 1 0 10 10 10 8 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 OWF46756.1 - 1.3e-25 89.7 12.1 7.7e-08 32.5 0.8 8.7 8 1 1 9 9 9 6 SdrD B-like domain DUF2012 PF09430.10 OWF46756.1 - 1.1e-18 67.5 0.1 0.005 17.0 0.0 8.0 6 1 1 8 8 8 4 Protein of unknown function (DUF2012) SpaA PF17802.1 OWF46756.1 - 1.7e-14 53.9 10.6 0.024 14.9 0.1 7.9 5 2 2 7 7 7 3 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 OWF46756.1 - 1.7e-14 53.5 22.8 1.3e-06 28.3 0.2 8.8 11 0 0 11 11 11 3 CarboxypepD_reg-like domain fn3_3 PF14686.6 OWF46756.1 - 1.1e-12 47.5 2.7 0.014 15.2 0.1 6.2 6 0 0 6 6 6 3 Polysaccharide lyase family 4, domain II MG4 PF17789.1 OWF46756.1 - 4.3e-05 23.6 0.1 0.012 15.8 0.0 3.9 3 0 0 3 3 3 1 Macroglobulin domain MG4 Dioxygenase_C PF00775.21 OWF46756.1 - 0.0092 15.4 1.7 7.7 5.9 0.0 5.0 5 3 1 6 6 6 1 Dioxygenase Y_Y_Y PF07495.13 OWF46756.1 - 0.012 15.5 3.2 41 4.2 0.1 5.1 5 0 0 5 5 5 0 Y_Y_Y domain EMP24_GP25L PF01105.24 OWF46756.1 - 0.1 12.5 0.7 5.3 6.9 0.0 3.9 4 2 1 5 5 5 0 emp24/gp25L/p24 family/GOLD DnaJ PF00226.31 OWF46757.1 - 1.7e-25 88.9 0.6 2.5e-25 88.4 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Mob1_phocein PF03637.17 OWF46758.1 - 3.2e-80 268.1 0.5 3.9e-80 267.8 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family Aurora-A_bind PF09041.10 OWF46758.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Aurora-A binding WAP PF00095.21 OWF46759.1 - 3.8e-07 30.4 17.2 3.8e-07 30.4 17.2 3.0 3 0 0 3 3 3 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lustrin_cystein PF14625.6 OWF46761.1 - 0.0023 18.2 10.0 0.0023 18.2 10.0 9.3 6 4 3 9 9 9 3 Lustrin, cysteine-rich repeated domain Ank_2 PF12796.7 OWF46766.1 - 7.3e-13 48.9 0.9 1.5e-05 25.5 0.3 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF46766.1 - 4.3e-08 32.8 2.0 0.4 11.4 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat ATG16 PF08614.11 OWF46766.1 - 1.3e-07 32.1 0.5 1.3e-07 32.1 0.5 2.4 2 1 0 2 2 1 1 Autophagy protein 16 (ATG16) Ank_4 PF13637.6 OWF46766.1 - 2e-07 31.4 1.6 0.093 13.3 0.0 4.6 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF46766.1 - 6.9e-07 29.4 0.4 3.2 8.4 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OWF46766.1 - 0.00083 19.6 3.3 0.072 13.4 0.1 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Tropomyosin_1 PF12718.7 OWF46766.1 - 0.013 15.6 3.9 0.035 14.3 3.9 1.7 1 0 0 1 1 1 0 Tropomyosin like Myosin_tail_1 PF01576.19 OWF46766.1 - 0.015 13.1 4.4 0.022 12.6 4.4 1.1 1 0 0 1 1 1 0 Myosin tail YojJ PF10372.9 OWF46766.1 - 0.047 13.8 1.9 0.12 12.5 1.9 1.7 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus BRE1 PF08647.11 OWF46766.1 - 0.29 11.2 4.3 0.65 10.1 4.3 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 OWF46766.1 - 0.34 10.7 3.5 0.72 9.6 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 OWF46766.1 - 0.51 9.6 4.6 1.1 8.5 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DnaJ PF00226.31 OWF46767.1 - 4.9e-17 61.8 1.9 3.6e-16 59.0 1.9 2.6 1 0 0 1 1 1 1 DnaJ domain Sec61_beta PF03911.16 OWF46767.1 - 0.054 13.5 0.9 0.1 12.7 0.9 1.4 1 0 0 1 1 1 0 Sec61beta family Ank_2 PF12796.7 OWF46768.1 - 2.5e-47 159.4 2.6 3.6e-10 40.3 0.2 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF46768.1 - 1.2e-46 156.1 7.5 1.4e-08 34.8 0.0 7.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF46768.1 - 2.8e-43 145.7 4.4 4.1e-10 40.0 0.1 6.9 2 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46768.1 - 2.1e-38 125.9 1.0 9e-05 22.6 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 OWF46768.1 - 4.3e-34 115.5 8.5 0.0001 22.6 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat MAM PF00629.23 OWF46772.1 - 6e-22 78.3 0.8 8.7e-22 77.7 0.8 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Sushi PF00084.20 OWF46772.1 - 2e-06 28.3 10.9 0.0029 18.2 0.9 2.8 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) MAM PF00629.23 OWF46773.1 - 5.8e-40 136.8 0.0 9.2e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu YrzK PF17449.2 OWF46773.1 - 1.6e-16 60.3 56.9 0.061 13.6 0.4 12.3 4 2 8 13 13 13 9 Uncharacterized YrzK-like Sushi PF00084.20 OWF46773.1 - 4.3e-09 36.8 2.4 0.00059 20.4 0.5 2.8 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Adeno_E3_CR2 PF02439.15 OWF46773.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rax2 PF12768.7 OWF46773.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 OWF46773.1 - 0.03 13.7 1.5 0.067 12.6 1.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 OWF46773.1 - 0.055 13.2 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OWF46773.1 - 0.089 12.9 6.4 0.15 12.1 6.4 1.3 1 0 0 1 1 1 0 Podoplanin PKD_channel PF08016.12 OWF46774.1 - 6.8e-67 226.0 14.0 6.8e-67 226.0 14.0 2.1 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 OWF46774.1 - 8.6e-11 42.4 0.1 2.2e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain BNR PF02012.20 OWF46774.1 - 0.1 12.7 2.0 0.49 10.6 0.1 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat UDPGT PF00201.18 OWF46775.1 - 2.5e-76 257.5 0.0 3.3e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OWF46775.1 - 0.0021 18.1 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain gag-asp_proteas PF13975.6 OWF46776.1 - 9.5e-08 32.5 0.0 2.7e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OWF46776.1 - 4.5e-06 27.2 0.0 1.5e-05 25.5 0.0 1.9 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.20 OWF46776.1 - 4.6e-05 23.7 0.0 0.00016 21.9 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 OWF46776.1 - 0.00056 19.7 0.2 0.0016 18.3 0.1 1.8 2 1 0 2 2 2 1 Aspartyl protease dUTPase PF00692.19 OWF46776.1 - 0.0097 15.6 0.1 0.024 14.3 0.1 1.7 2 0 0 2 2 2 1 dUTPase Lipase_GDSL_2 PF13472.6 OWF46777.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PHD PF00628.29 OWF46778.1 - 3.5e-08 33.2 9.7 5e-08 32.7 9.7 1.3 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 OWF46778.1 - 0.0093 16.3 8.9 0.18 12.2 4.6 2.1 2 0 0 2 2 2 2 C1 domain Prok-RING_2 PF14445.6 OWF46778.1 - 0.11 12.6 7.0 1.6 9.0 1.9 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 zf-RING_9 PF13901.6 OWF46778.1 - 0.12 12.4 8.5 2.2 8.2 5.7 2.1 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon zf-C2H2_jaz PF12171.8 OWF46778.1 - 0.28 11.5 0.7 0.28 11.5 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_2 PF13639.6 OWF46778.1 - 0.3 11.4 9.7 0.5 10.7 9.7 1.3 1 1 0 1 1 1 0 Ring finger domain Integrase_H2C2 PF17921.1 OWF46779.1 - 1.8e-08 34.3 0.4 4.3e-08 33.1 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OWF46779.1 - 6.3e-07 29.6 0.1 1.7e-05 25.0 0.0 2.3 1 1 1 2 2 2 1 Integrase core domain DDHD PF02862.17 OWF46781.1 - 0.064 13.4 3.2 0.098 12.8 3.2 1.4 1 0 0 1 1 1 0 DDHD domain Hamartin PF04388.12 OWF46781.1 - 0.66 8.6 15.1 0.83 8.2 15.1 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 OWF46781.1 - 1.2 7.7 7.8 1.6 7.2 7.8 1.2 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 OWF46781.1 - 1.2 7.6 11.1 1.7 7.1 11.1 1.1 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 OWF46781.1 - 9.5 3.2 12.6 12 2.8 12.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MMR_HSR1 PF01926.23 OWF46782.1 - 2.6e-14 53.2 0.6 5.3e-12 45.8 0.0 3.2 3 1 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF46782.1 - 1.7e-05 24.4 0.0 0.0049 16.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF46782.1 - 0.00081 19.3 2.2 0.34 10.8 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase SGT1 PF07093.11 OWF46782.1 - 0.11 10.9 11.7 0.14 10.5 11.7 1.2 1 0 0 1 1 1 0 SGT1 protein Dynamin_N PF00350.23 OWF46782.1 - 1.4 8.9 13.8 3.1 7.8 0.1 3.9 3 2 0 3 3 3 0 Dynamin family CDC45 PF02724.14 OWF46782.1 - 2.1 6.5 14.8 3.8 5.7 14.8 1.4 1 0 0 1 1 1 0 CDC45-like protein 7TM_GPCR_Srw PF10324.9 OWF46783.1 - 1.4e-29 103.5 25.6 2.2e-29 102.8 25.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF46783.1 - 4.9e-12 45.7 19.2 7.7e-12 45.1 19.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) KH_1 PF00013.29 OWF46784.1 - 1.9e-178 578.6 65.4 1e-15 57.3 0.4 16.1 16 0 0 16 16 16 16 KH domain SLS PF14611.6 OWF46784.1 - 7.9e-20 71.6 22.7 0.0081 16.0 0.1 9.0 2 2 6 9 9 9 7 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 OWF46784.1 - 9.6e-18 63.8 33.9 0.054 13.3 1.3 12.7 12 1 1 13 13 13 9 KH domain MOEP19 PF16005.5 OWF46784.1 - 8.4e-07 28.9 6.7 0.084 12.9 0.1 7.5 8 1 1 9 9 9 1 KH-like RNA-binding domain BMC PF00936.19 OWF46784.1 - 2.3e-05 24.3 1.1 8.1 6.5 0.0 6.3 8 0 0 8 8 8 1 BMC domain KH_5 PF13184.6 OWF46784.1 - 0.00034 20.6 25.0 7.8 6.7 0.0 9.9 10 1 1 11 11 11 2 NusA-like KH domain DUF4140 PF13600.6 OWF46784.1 - 0.21 12.0 7.5 0.32 11.4 0.2 4.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.17 OWF46784.1 - 0.33 10.9 4.3 6.6 6.7 0.0 4.4 4 0 0 4 4 4 0 Prefoldin subunit KH_4 PF13083.6 OWF46784.1 - 0.37 10.7 0.0 0.37 10.7 0.0 8.5 10 1 1 11 11 11 0 KH domain DUF1664 PF07889.12 OWF46784.1 - 0.65 10.0 17.5 0.076 13.1 0.5 5.7 6 1 0 6 6 6 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OWF46784.1 - 2 8.4 8.3 5.2 7.1 0.1 4.4 5 0 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSP_1 PF00090.19 OWF46785.1 - 1.1e-25 89.6 46.2 4.6e-10 39.6 7.9 4.9 4 0 0 4 4 4 3 Thrombospondin type 1 domain Gal_Lectin PF02140.18 OWF46785.1 - 1.9e-09 37.8 3.1 1.8e-06 28.3 0.0 3.9 4 0 0 4 4 4 2 Galactose binding lectin domain Complex1_49kDa PF00346.19 OWF46785.1 - 0.18 10.8 0.0 0.43 9.6 0.0 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ephrin_rec_like PF07699.13 OWF46786.1 - 0.00063 19.5 6.0 0.007 16.1 1.4 2.9 2 0 0 2 2 2 2 Putative ephrin-receptor like TNFR_c6 PF00020.18 OWF46786.1 - 0.00073 19.9 3.3 0.00073 19.9 3.3 3.8 3 1 0 3 3 3 1 TNFR/NGFR cysteine-rich region Carboxyl_trans PF01039.22 OWF46787.1 - 4.4e-152 507.2 0.0 5.3e-152 506.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain FAA_hydrolase PF01557.18 OWF46788.1 - 1.5e-53 181.7 0.0 2.1e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OWF46788.1 - 9.4e-36 122.3 0.0 1.5e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Ifi-6-16 PF06140.13 OWF46789.1 - 1e-12 47.7 36.3 1.5e-12 47.2 35.8 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF975 PF06161.11 OWF46792.1 - 0.11 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) MFS_1 PF07690.16 OWF46793.1 - 9.6e-50 169.5 27.7 1.3e-49 169.0 27.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4212 PF13937.6 OWF46793.1 - 0.94 9.9 7.3 0.21 12.0 1.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF1011 PF06237.12 OWF46794.1 - 7.7e-29 99.9 7.2 7.7e-29 99.9 7.2 3.9 4 1 1 5 5 5 1 Protein of unknown function (DUF1011) TatD_DNase PF01026.21 OWF46795.1 - 3.4e-40 138.0 0.0 4.4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase SpoIIIAH PF12685.7 OWF46796.1 - 0.66 9.8 14.3 0.5 10.2 4.9 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Maelstrom PF13017.6 OWF46797.1 - 5.3e-37 127.6 0.0 7.9e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.10 OWF46797.1 - 9.7e-16 58.1 0.1 2.1e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 OWF46797.1 - 3.8e-07 30.4 0.3 7.2e-07 29.5 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box BIR PF00653.21 OWF46798.1 - 5.9e-26 90.9 5.7 2.6e-16 60.0 0.1 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain FGGY_N PF00370.21 OWF46799.1 - 1.7e-77 260.3 0.3 8.1e-77 258.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OWF46799.1 - 8.1e-65 218.3 1.2 2.1e-64 216.9 1.2 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Acetyltransf_18 PF18014.1 OWF46801.1 - 1.4e-14 54.0 0.0 1.5e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF46801.1 - 0.047 13.6 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peroxidase_ext PF11895.8 OWF46802.1 - 0.027 14.4 2.0 10 6.1 0.0 3.4 3 0 0 3 3 3 0 Fungal peroxidase extension region NPCBM_assoc PF10633.9 OWF46802.1 - 0.33 11.2 3.5 43 4.4 0.1 4.1 3 2 1 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase US22 PF02393.16 OWF46802.1 - 0.45 10.8 5.9 26 5.1 0.2 3.3 2 1 1 3 3 3 0 US22 like PurK_C PF17769.1 OWF46805.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain Sporozoite_P67 PF05642.11 OWF46806.1 - 2.5 6.1 3.6 2.4 6.1 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraT PF05818.12 OWF46806.1 - 3.8 7.1 7.6 4.4 6.9 7.6 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein LRRC37AB_C PF14914.6 OWF46807.1 - 0.00077 19.4 1.0 0.0012 18.7 1.0 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Orf78 PF06024.12 OWF46807.1 - 0.023 15.0 0.4 0.044 14.1 0.4 1.5 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OWF46807.1 - 0.024 15.5 1.8 0.071 14.0 0.2 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF46807.1 - 0.061 13.2 1.9 0.075 12.9 0.8 1.6 1 1 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 OWF46807.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EVI2A PF05399.11 OWF46807.1 - 6.5 6.3 7.9 3.2 7.3 6.0 1.7 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Mab-21 PF03281.14 OWF46808.1 - 3.5e-24 85.6 0.1 3.5e-24 85.6 0.1 1.7 2 0 0 2 2 2 1 Mab-21 protein OTU PF02338.19 OWF46808.1 - 1.4e-11 45.0 0.0 3.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Ribo_biogen_C PF04034.13 OWF46808.1 - 0.13 11.9 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein, C-terminal Mab-21 PF03281.14 OWF46809.1 - 6.3e-23 81.5 1.4 1.2e-22 80.5 1.4 1.5 1 0 0 1 1 1 1 Mab-21 protein OTU PF02338.19 OWF46809.1 - 1.8e-11 44.6 0.0 5.4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease zf-UDP PF14569.6 OWF46809.1 - 0.55 10.4 6.1 1.1 9.4 4.4 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger FYVE PF01363.21 OWF46809.1 - 3 8.1 15.1 0.66 10.2 8.5 2.9 3 0 0 3 3 3 0 FYVE zinc finger Roc PF08477.13 OWF46810.1 - 5.6e-09 36.3 0.1 7.7e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF46810.1 - 2.3e-08 34.1 0.6 0.016 15.3 0.2 3.6 3 0 0 3 3 3 2 Death domain COR PF16095.5 OWF46810.1 - 6.4e-08 32.6 0.4 1.6e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain G-alpha PF00503.20 OWF46810.1 - 0.00018 20.8 0.1 0.00029 20.1 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.27 OWF46810.1 - 0.035 14.6 0.1 0.098 13.2 0.1 1.7 1 0 0 1 1 1 0 ABC transporter PRA1 PF03208.19 OWF46811.1 - 1.1e-36 125.6 0.1 1.8e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 PRA1 family protein DHHC PF01529.20 OWF46811.1 - 0.86 9.7 6.6 0.68 10.0 4.1 2.0 2 1 0 2 2 2 0 DHHC palmitoyltransferase HIG_1_N PF04588.13 OWF46811.1 - 2.8 8.2 0.0 2.8 8.2 0.0 3.0 4 0 0 4 4 4 0 Hypoxia induced protein conserved region LRR_9 PF14580.6 OWF46812.1 - 3.7e-05 23.3 1.4 0.081 12.4 0.0 3.3 1 1 4 5 5 5 1 Leucine-rich repeat ubiquitin PF00240.23 OWF46812.1 - 0.00021 20.9 0.0 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family LRR_4 PF12799.7 OWF46812.1 - 0.00031 21.1 14.3 0.01 16.2 0.5 5.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) FYRN PF05964.14 OWF46812.1 - 0.026 14.3 7.6 15 5.6 0.1 4.8 4 1 1 5 5 5 0 F/Y-rich N-terminus Ubiquitin_2 PF14560.6 OWF46812.1 - 0.059 13.8 0.0 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain LRR_6 PF13516.6 OWF46812.1 - 0.074 13.1 13.3 1.7 8.9 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 OWF46812.1 - 0.22 11.3 15.4 0.27 11.0 0.9 4.0 4 1 0 4 4 4 0 Leucine rich repeat Mab-21 PF03281.14 OWF46813.1 - 5.1e-27 94.9 1.2 8.4e-27 94.2 1.2 1.3 1 0 0 1 1 1 1 Mab-21 protein OTU PF02338.19 OWF46813.1 - 1.5e-13 51.3 0.0 5e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease Oxidored_molyb PF00174.19 OWF46814.1 - 1e-54 184.7 0.0 1.8e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OWF46814.1 - 3.3e-42 143.8 0.5 8.3e-42 142.5 0.1 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 OWF46814.1 - 1.6e-15 57.0 0.0 3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 OWF46814.1 - 0.57 10.4 4.5 0.23 11.6 1.1 2.3 2 0 0 2 2 2 0 BNR/Asp-box repeat C1q PF00386.21 OWF46815.1 - 1.8e-16 60.5 0.0 2.8e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 C1q domain DUF812 PF05667.11 OWF46815.1 - 0.19 10.6 0.3 0.25 10.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NblA PF04485.12 OWF46816.1 - 5.9e-05 23.4 30.1 26 5.3 0.1 10.1 2 1 9 13 13 13 4 Phycobilisome degradation protein nblA DUF924 PF06041.11 OWF46816.1 - 0.027 14.6 12.9 4.4 7.4 1.9 4.9 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF924) SATase_N PF06426.14 OWF46816.1 - 1.6 9.2 10.0 27 5.2 3.2 3.4 1 1 2 3 3 3 0 Serine acetyltransferase, N-terminal Lectin_C PF00059.21 OWF46817.1 - 4.8e-07 30.5 0.0 1.1e-06 29.4 0.0 1.7 1 1 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF46817.1 - 0.0021 18.0 0.3 0.0034 17.3 0.3 1.3 1 0 0 1 1 1 1 PAN domain DUF4377 PF14302.6 OWF46817.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) PIH1_CS PF18201.1 OWF46818.1 - 2.8e-13 50.1 0.0 5.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain PIH1 PF08190.12 OWF46818.1 - 3.1e-06 26.7 2.1 3.2e-05 23.5 2.0 2.3 1 1 0 1 1 1 1 PIH1 N-terminal domain ArsA_HSP20 PF17886.1 OWF46818.1 - 0.0026 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA NKAP PF15692.5 OWF46819.1 - 4.8e-05 24.0 18.7 4.8e-05 24.0 18.7 6.0 2 2 3 5 5 5 1 NF-kappa-B-activating protein MORN PF02493.20 OWF46820.1 - 6.1e-37 123.3 50.9 4e-07 29.5 0.3 7.7 8 0 0 8 8 8 7 MORN repeat Lectin_C PF00059.21 OWF46821.1 - 3.1e-25 89.0 19.2 5.3e-10 40.0 2.3 3.6 3 0 0 3 3 3 3 Lectin C-type domain AAA_16 PF13191.6 OWF46821.1 - 0.00016 22.1 0.0 0.00028 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OWF46821.1 - 0.0078 16.3 0.0 0.0078 16.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OWF46821.1 - 0.01 16.2 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 OWF46821.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OWF46821.1 - 0.022 14.7 0.1 0.25 11.3 0.0 2.6 2 1 0 3 3 3 0 RsgA GTPase FDF PF09532.10 OWF46821.1 - 0.044 14.7 1.2 0.085 13.7 1.2 1.4 1 0 0 1 1 1 0 FDF domain DUF815 PF05673.13 OWF46821.1 - 0.044 12.9 0.0 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 OWF46821.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF46823.1 - 2.3e-07 31.3 0.0 5.1e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OWF46823.1 - 0.00016 21.0 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 OWF46823.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OWF46823.1 - 0.0029 17.7 0.0 0.0067 16.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OWF46823.1 - 0.0034 17.1 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.13 OWF46823.1 - 0.0037 16.4 0.1 0.0072 15.4 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 OWF46823.1 - 0.0082 16.1 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OWF46823.1 - 0.017 15.2 1.0 0.34 10.9 0.8 2.3 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 OWF46823.1 - 0.027 13.6 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 OWF46823.1 - 0.038 13.3 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 OWF46823.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 OWF46823.1 - 0.12 11.8 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 OWF46823.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AIG1 PF04548.16 OWF46823.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family CNOT1_HEAT PF16418.5 OWF46823.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat SMC_N PF02463.19 OWF46823.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Plasmid_RAQPRD PF09686.10 OWF46824.1 - 0.0066 16.6 0.3 1.6e+02 2.6 0.0 7.9 6 3 6 12 12 12 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF2474 PF10617.9 OWF46824.1 - 0.032 14.1 28.2 6.4 6.7 0.0 10.8 5 3 5 12 12 12 0 Protein of unknown function (DUF2474) Baculo_p74 PF04583.12 OWF46824.1 - 3 7.3 7.3 70 2.8 0.1 4.5 3 2 2 5 5 5 0 Baculoviridae p74 conserved region Nairo_nucleo PF02477.15 OWF46824.1 - 3.2 6.5 7.6 16 4.2 0.2 4.7 1 1 3 5 5 5 0 Nucleocapsid N protein CwfJ_C_1 PF04677.15 OWF46824.1 - 6.6 6.6 14.4 97 2.9 0.3 7.0 5 3 1 6 6 6 0 Protein similar to CwfJ C-terminus 1 UPF0051 PF01458.17 OWF46825.1 - 1.5e-05 24.8 0.0 17 5.0 0.0 6.7 1 1 3 5 5 5 2 Uncharacterized protein family (UPF0051) Ycf9 PF01737.17 OWF46825.1 - 0.028 14.3 0.2 1.5e+02 2.3 0.0 7.0 5 1 0 7 7 7 0 YCF9 DUF1664 PF07889.12 OWF46826.1 - 5.2e-28 97.6 38.1 0.0002 21.4 0.3 10.0 1 1 9 10 10 10 8 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 OWF46826.1 - 1.3e-22 79.9 32.8 0.02 15.2 0.4 9.2 1 1 7 10 10 10 10 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 OWF46826.1 - 5.2e-18 65.1 32.1 0.034 14.4 0.2 9.2 1 1 8 9 9 9 7 Bacterial protein of unknown function (DUF948) YabA PF06156.13 OWF46826.1 - 5e-14 52.8 0.0 17 6.2 0.0 10.9 1 1 10 11 11 11 0 Initiation control protein YabA COG2 PF06148.11 OWF46826.1 - 7.6e-14 51.9 4.4 4.8 7.3 0.0 9.1 1 1 10 11 11 11 4 COG (conserved oligomeric Golgi) complex component, COG2 UPF0184 PF03670.13 OWF46826.1 - 9.3e-13 48.4 43.9 24 5.4 0.2 19.3 2 2 22 24 24 24 0 Uncharacterised protein family (UPF0184) Flagellar_rod PF05149.12 OWF46826.1 - 8e-09 35.4 34.7 1.7e+02 1.5 0.2 12.6 1 1 1 3 3 2 0 Paraflagellar rod protein Collagen_mid PF15984.5 OWF46826.1 - 2.5e-08 33.9 18.9 77 2.9 12.6 7.3 1 1 1 2 2 2 0 Bacterial collagen, middle region HALZ PF02183.18 OWF46826.1 - 2.2e-07 31.0 47.5 8.7 6.7 0.1 20.6 8 2 6 21 21 21 2 Homeobox associated leucine zipper EzrA PF06160.12 OWF46826.1 - 4.5e-07 28.4 3.6 0.22 9.7 0.1 4.3 1 1 3 4 4 4 3 Septation ring formation regulator, EzrA FNIP_C PF14638.6 OWF46826.1 - 0.00047 19.9 70.6 1.8 8.1 1.2 11.8 1 1 5 6 6 5 1 Folliculin-interacting protein C-terminus AIP3 PF03915.13 OWF46826.1 - 0.029 13.5 0.4 2.7 7.0 0.4 3.0 1 1 0 1 1 1 0 Actin interacting protein 3 MCPsignal PF00015.21 OWF46826.1 - 0.068 13.0 33.9 5.3e+02 0.3 0.1 7.4 1 1 1 2 2 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DnaJ-X PF14308.6 OWF46826.1 - 0.074 12.5 69.9 53 3.2 2.5 10.0 1 1 4 5 5 4 0 X-domain of DnaJ-containing DUF4744 PF15918.5 OWF46826.1 - 1.3 9.9 140.6 1.6e+02 3.2 8.1 14.2 1 1 9 10 10 7 0 Domain of unknown function (DUF4744) MFS_1 PF07690.16 OWF46827.1 - 4.5e-38 131.1 27.9 4.2e-21 75.3 10.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily zf-H2C2 PF09337.10 OWF46827.1 - 0.22 11.7 1.7 0.4 10.9 0.7 1.9 2 0 0 2 2 2 0 H2C2 zinc finger ORC6 PF05460.13 OWF46827.1 - 0.45 9.7 9.2 0.4 9.9 7.0 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Pap_E4 PF02711.14 OWF46827.1 - 4 8.5 5.3 2.4 9.2 1.4 2.3 2 0 0 2 2 2 0 E4 protein Peptidase_M54 PF07998.11 OWF46828.1 - 1.5e-17 64.2 0.1 2.6e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_3 PF13582.6 OWF46828.1 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 OWF46828.1 - 0.00047 18.9 0.2 0.00071 18.3 0.2 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_4 PF13583.6 OWF46828.1 - 0.00057 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF46828.1 - 0.0041 17.3 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 OWF46828.1 - 0.0087 15.0 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 OWF46828.1 - 0.025 14.5 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 OWF46828.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 OWF46828.1 - 0.17 11.5 0.2 0.25 10.9 0.2 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Tetraspanin PF00335.20 OWF46829.1 - 2e-27 96.4 12.9 2.5e-27 96.1 12.9 1.0 1 0 0 1 1 1 1 Tetraspanin family ASFV_J13L PF05568.11 OWF46829.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.2 1 1 1 2 2 2 0 African swine fever virus J13L protein CBP_BcsG PF11658.8 OWF46829.1 - 0.22 9.9 2.6 0.3 9.4 2.6 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF5337 PF17272.2 OWF46829.1 - 1.7 8.6 0.0 1.7 8.6 0.0 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5337) DUF2981 PF11200.8 OWF46829.1 - 2.2 7.9 5.2 3.5 7.3 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Gram_pos_anchor PF00746.21 OWF46829.1 - 4.2 7.4 9.6 0.76 9.8 1.0 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Ets PF00178.22 OWF46830.1 - 4.7e-34 116.7 0.4 4.7e-34 116.7 0.4 1.8 2 0 0 2 2 2 1 Ets-domain GABP-alpha PF11620.8 OWF46830.1 - 7.4e-33 112.6 1.3 7.4e-33 112.6 1.3 1.8 2 0 0 2 2 2 1 GA-binding protein alpha chain SAM_PNT PF02198.16 OWF46830.1 - 7.8e-27 93.1 0.3 2.1e-26 91.7 0.3 1.8 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 OWF46830.1 - 0.12 12.1 0.0 3.2 7.6 0.0 3.0 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) ATP-synt_F6 PF05511.11 OWF46831.1 - 3e-17 62.8 0.2 3.9e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.9 OWF46831.1 - 0.0034 17.4 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Death PF00531.22 OWF46832.1 - 2.8e-15 56.2 0.3 5.3e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 Death domain Roc PF08477.13 OWF46832.1 - 1e-12 48.4 0.0 6.1e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF46832.1 - 1.8e-08 34.4 0.0 4.7e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Ras PF00071.22 OWF46832.1 - 2.4e-08 33.8 0.0 5e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Ras family AAA_22 PF13401.6 OWF46832.1 - 0.0053 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OWF46832.1 - 0.0085 16.6 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OWF46832.1 - 0.018 15.1 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OWF46832.1 - 0.035 14.3 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF46832.1 - 0.078 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 OWF46832.1 - 0.088 13.2 0.0 0.54 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 OWF46832.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region CLP1_P PF16575.5 OWF46832.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Collagen PF01391.18 OWF46833.1 - 0.00052 19.7 3.2 0.00087 19.0 3.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) C1q PF00386.21 OWF46834.1 - 1.4e-20 73.8 1.7 2.3e-20 73.1 0.1 2.0 2 1 0 2 2 2 1 C1q domain Collagen PF01391.18 OWF46834.1 - 3.4e-07 29.9 13.3 5.6e-07 29.2 13.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) AICARFT_IMPCHas PF01808.18 OWF46835.1 - 0.054 12.9 0.3 0.1 12.0 0.2 1.5 1 1 0 1 1 1 0 AICARFT/IMPCHase bienzyme AA_permease PF00324.21 OWF46836.1 - 5.5e-41 140.7 16.1 2.1e-37 128.9 13.5 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 OWF46836.1 - 2.5e-17 63.1 1.8 3.9e-10 39.3 0.0 3.3 2 1 1 3 3 3 3 Solute carrier family 12 SLC12 PF03522.15 OWF46837.1 - 6.6e-14 51.8 0.1 3e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Solute carrier family 12 TIP49 PF06068.13 OWF46838.1 - 1.1e-163 544.4 3.7 1.6e-163 544.0 3.7 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OWF46838.1 - 1.9e-29 101.6 0.8 5.8e-29 100.0 0.8 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OWF46838.1 - 1.4e-09 38.5 1.8 2.1e-06 28.2 0.1 3.1 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OWF46838.1 - 1.2e-07 31.6 0.5 0.0013 18.5 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 OWF46838.1 - 1.1e-06 28.2 0.4 2.2e-06 27.2 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 OWF46838.1 - 4.3e-06 27.2 0.2 3.3e-05 24.3 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OWF46838.1 - 1.6e-05 24.9 0.1 0.01 15.9 0.0 3.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF46838.1 - 2.5e-05 24.5 0.4 0.11 12.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain Sigma54_activat PF00158.26 OWF46838.1 - 0.0002 21.1 0.1 0.15 11.8 0.1 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 OWF46838.1 - 0.0002 21.0 0.1 0.00079 19.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OWF46838.1 - 0.00023 21.5 6.7 0.0015 18.9 3.5 3.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OWF46838.1 - 0.00088 18.7 1.0 0.035 13.5 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 OWF46838.1 - 0.0023 17.2 0.1 0.0035 16.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 OWF46838.1 - 0.0027 18.3 0.9 0.0027 18.3 0.9 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 OWF46838.1 - 0.0096 15.7 1.1 0.36 10.5 0.5 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OWF46838.1 - 0.011 15.5 0.4 0.023 14.4 0.4 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OWF46838.1 - 0.011 15.2 0.2 0.076 12.5 0.0 2.4 2 1 1 3 3 3 0 P-loop containing dynein motor region PIF1 PF05970.14 OWF46838.1 - 0.023 13.9 1.1 2.1 7.4 0.2 2.3 2 0 0 2 2 2 0 PIF1-like helicase NACHT PF05729.12 OWF46838.1 - 0.038 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 OWF46838.1 - 0.048 13.4 0.7 0.22 11.2 0.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF46838.1 - 0.059 13.5 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OWF46838.1 - 0.075 12.8 0.3 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OWF46838.1 - 0.083 12.2 0.2 0.19 11.0 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 OWF46838.1 - 0.098 13.1 1.8 0.18 12.3 0.8 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 OWF46838.1 - 0.11 12.5 1.1 2.3 8.2 1.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OWF46838.1 - 0.14 11.6 5.6 0.13 11.7 0.6 2.7 3 0 0 3 3 3 0 PhoH-like protein Parvo_NS1 PF01057.17 OWF46838.1 - 0.15 11.1 0.2 0.27 10.3 0.2 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IQ PF00612.27 OWF46839.1 - 1.6e-17 61.5 3.7 0.00022 20.8 0.4 4.1 3 0 0 3 3 3 3 IQ calmodulin-binding motif LRR_4 PF12799.7 OWF46839.1 - 1.2e-15 57.4 33.2 6e-06 26.5 1.5 6.0 4 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF46839.1 - 1.9e-12 46.7 32.8 5.2e-07 29.3 4.3 4.9 3 2 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 OWF46839.1 - 0.55 11.0 32.1 12 6.9 0.1 8.6 7 1 1 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF46839.1 - 8.5 6.7 29.6 0.62 10.3 0.5 7.0 8 0 0 8 8 8 0 Leucine Rich repeat Kelch_4 PF13418.6 OWF46840.1 - 3.8e-21 74.8 14.1 2.2e-06 27.6 0.9 6.4 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF46840.1 - 4.6e-20 71.4 24.4 1.9e-07 31.2 0.2 7.9 7 2 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF46840.1 - 8.3e-14 51.3 12.2 0.002 18.3 0.0 6.1 5 2 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OWF46840.1 - 1.1e-10 40.9 6.4 0.00019 20.9 0.3 4.5 5 0 0 5 5 5 3 Kelch motif Cytochrom_B561 PF03188.16 OWF46840.1 - 9.2e-09 35.5 10.8 9.2e-09 35.5 10.8 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Kelch_5 PF13854.6 OWF46840.1 - 3.2e-08 33.4 10.3 0.00067 19.6 0.0 6.7 6 1 0 6 6 6 1 Kelch motif Kelch_2 PF07646.15 OWF46840.1 - 6.7e-08 32.2 8.0 0.077 13.0 0.1 5.6 5 1 0 5 5 5 3 Kelch motif DUF4231 PF14015.6 OWF46840.1 - 0.38 11.3 6.7 8 7.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) CD20 PF04103.15 OWF46840.1 - 0.39 10.8 15.0 0.45 10.6 2.4 2.7 2 0 0 2 2 2 0 CD20-like family DUF373 PF04123.13 OWF46840.1 - 2 7.8 7.0 0.9 8.9 3.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) QVR PF17064.5 OWF46841.1 - 0.0018 18.5 4.8 0.0061 16.8 0.5 2.2 2 0 0 2 2 2 2 Sleepless protein Attractin PF08037.11 OWF46841.1 - 0.26 11.3 4.5 1.2 9.2 0.4 2.6 2 1 0 2 2 2 0 Attractin family bZIP_1 PF00170.21 OWF46844.1 - 3.6e-17 62.2 15.7 6.6e-17 61.4 15.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF46844.1 - 2.7e-08 34.2 10.6 5.4e-08 33.2 10.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OWF46844.1 - 6.6e-07 29.3 13.7 6.6e-07 29.3 13.7 1.9 1 1 1 2 2 2 2 Basic region leucine zipper FTA4 PF13093.6 OWF46844.1 - 0.00071 19.5 0.4 0.0012 18.8 0.4 1.4 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ADIP PF11559.8 OWF46844.1 - 0.0018 18.4 5.0 0.0018 18.4 5.0 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4404 PF14357.6 OWF46844.1 - 0.0047 17.5 1.6 0.013 16.1 1.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) TRPM_tetra PF16519.5 OWF46844.1 - 0.0091 16.1 1.2 0.03 14.4 1.2 1.8 1 0 0 1 1 1 1 Tetramerisation domain of TRPM DUF4407 PF14362.6 OWF46844.1 - 0.0093 15.4 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 OWF46844.1 - 0.011 16.2 7.9 0.024 15.1 7.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 OWF46844.1 - 0.025 14.8 3.4 0.77 10.1 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2207 PF09972.9 OWF46844.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3450 PF11932.8 OWF46844.1 - 0.026 13.8 3.6 0.057 12.7 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RFX5_DNA_bdg PF14621.6 OWF46844.1 - 0.029 14.1 1.3 0.05 13.4 1.3 1.3 1 0 0 1 1 1 0 RFX5 DNA-binding domain LMBR1 PF04791.16 OWF46844.1 - 0.063 12.2 0.5 0.091 11.7 0.0 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein Jnk-SapK_ap_N PF09744.9 OWF46844.1 - 0.089 13.0 10.3 0.17 12.1 10.3 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 OWF46844.1 - 0.23 10.3 7.4 0.41 9.5 7.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 OWF46844.1 - 0.24 11.8 3.1 1.1 9.6 0.9 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 OWF46844.1 - 0.38 10.5 11.9 0.77 9.5 11.9 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 OWF46844.1 - 0.41 10.0 13.5 0.88 8.9 13.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DivIC PF04977.15 OWF46844.1 - 0.52 10.1 6.5 0.37 10.6 4.3 1.8 1 1 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 OWF46844.1 - 0.55 10.3 8.2 1.2 9.2 8.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 OWF46844.1 - 0.62 10.7 4.8 0.68 10.6 2.9 2.0 1 1 0 1 1 1 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 OWF46844.1 - 2.3 8.3 13.8 1.3 9.0 11.8 1.6 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 OWF46844.1 - 2.9 5.7 5.1 5 4.9 5.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 OWF46844.1 - 9.4 4.0 6.4 1.4 6.8 2.4 1.5 2 0 0 2 2 2 0 Prominin AAA_6 PF12774.7 OWF46845.1 - 1.6e-159 530.2 0.1 2.6e-157 522.9 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF46845.1 - 1.1e-146 489.0 7.3 1.1e-146 489.0 7.3 4.3 4 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF46845.1 - 6.1e-117 390.2 1.6 1.8e-116 388.7 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF46845.1 - 1.7e-101 339.0 0.0 1.7e-101 339.0 0.0 2.9 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF46845.1 - 1.5e-92 308.7 1.9 2.7e-91 304.6 0.3 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF46845.1 - 5.1e-81 270.5 0.0 6.5e-76 253.9 0.0 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF46845.1 - 2.2e-58 196.7 0.2 7.4e-58 195.0 0.1 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF46845.1 - 1.4e-50 172.2 7.0 1.4e-50 172.2 7.0 1.6 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF46845.1 - 1.2e-45 154.4 0.2 1.8e-44 150.6 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF46845.1 - 1.7e-32 112.2 1.9 3.1e-32 111.3 0.1 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OWF46845.1 - 6.4e-22 77.7 0.1 3.6e-21 75.2 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OWF46845.1 - 2.1e-19 69.9 0.0 1.2e-05 25.4 0.0 6.1 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 OWF46845.1 - 3.8e-07 30.6 2.7 0.16 12.4 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF46845.1 - 2.3e-06 27.9 0.1 0.49 10.7 0.0 4.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 OWF46845.1 - 3e-05 24.5 0.7 1.4 9.3 0.0 5.2 5 0 0 5 5 5 1 AAA ATPase domain T2SSE PF00437.20 OWF46845.1 - 5.5e-05 22.3 0.1 0.14 11.2 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein DEAD PF00270.29 OWF46845.1 - 0.00017 21.4 0.8 0.33 10.7 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OWF46845.1 - 0.00023 21.2 2.0 0.68 9.9 0.0 3.7 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.6 OWF46845.1 - 0.00035 21.1 0.1 0.15 12.6 0.0 4.5 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 OWF46845.1 - 0.0011 18.4 0.7 1.8 7.9 0.0 3.3 5 0 0 5 5 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OWF46845.1 - 0.0012 18.6 1.0 6.3 6.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 OWF46845.1 - 0.0045 16.5 1.2 0.35 10.3 0.0 3.5 3 0 0 3 3 3 1 PhoH-like protein RNA_helicase PF00910.22 OWF46845.1 - 0.0048 17.3 0.1 12 6.3 0.0 4.4 3 0 0 3 3 3 0 RNA helicase DUF853 PF05872.12 OWF46845.1 - 0.0067 15.1 1.7 7.6 5.0 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 OWF46845.1 - 0.13 12.5 0.4 72 3.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 OWF46845.1 - 0.22 11.1 3.5 12 5.4 0.1 3.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PRD PF00874.20 OWF46845.1 - 0.29 11.5 2.6 2.7 8.4 2.6 2.8 1 0 0 1 1 1 0 PRD domain AAA_19 PF13245.6 OWF46845.1 - 1 9.7 10.8 7.2 6.9 0.1 5.1 5 0 0 5 5 4 0 AAA domain WD40 PF00400.32 OWF46846.1 - 1.4e-22 79.5 8.3 2.9e-06 27.9 1.5 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46846.1 - 4.5e-14 52.5 0.0 0.012 15.9 0.0 4.8 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OWF46846.1 - 3.9e-07 29.8 0.4 0.18 11.8 0.1 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OWF46846.1 - 4.9e-05 22.4 0.2 0.069 12.1 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF46846.1 - 0.00022 21.1 0.2 1.5 8.7 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 OWF46846.1 - 0.025 14.3 2.2 8.9 6.1 0.0 4.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Tub PF01167.18 OWF46847.1 - 6.4e-30 104.7 0.4 9.9e-26 91.0 1.1 3.2 2 1 0 2 2 2 2 Tub family ANAPC4_WD40 PF12894.7 OWF46847.1 - 2.2e-06 27.8 1.9 0.055 13.8 0.1 5.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain SOCS_box PF07525.16 OWF46847.1 - 0.00078 19.8 1.2 0.0017 18.6 1.2 1.6 1 0 0 1 1 1 1 SOCS box IKI3 PF04762.12 OWF46847.1 - 0.018 13.0 0.1 0.033 12.2 0.1 1.4 1 0 0 1 1 1 0 IKI3 family PD40 PF07676.12 OWF46847.1 - 0.12 12.4 0.8 21 5.2 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 OWF46847.1 - 0.39 11.7 2.8 22 6.1 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat RRM_1 PF00076.22 OWF46848.1 - 3.2e-63 209.5 3.3 1.7e-18 66.2 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OWF46848.1 - 1.8e-05 24.6 0.1 0.47 10.2 0.0 3.9 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 OWF46848.1 - 0.0066 16.4 0.4 0.17 11.9 0.0 3.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OWF46848.1 - 0.0078 15.8 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 OWF46848.1 - 0.063 12.9 0.0 27 4.5 0.1 3.5 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Arm PF00514.23 OWF46849.1 - 2.1e-84 275.2 6.7 2.3e-13 49.6 0.0 8.9 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OWF46849.1 - 1.7e-28 98.9 2.1 7.9e-27 93.5 3.9 2.5 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 OWF46849.1 - 2.5e-22 78.2 2.2 3.5e-22 77.7 0.7 2.0 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 OWF46849.1 - 4.7e-21 74.9 0.1 1.7e-08 34.8 0.0 5.3 3 1 3 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 OWF46849.1 - 1.6e-15 57.2 0.1 5.7e-06 26.6 0.0 6.0 1 1 3 6 6 6 4 HEAT repeats HEAT PF02985.22 OWF46849.1 - 1.3e-11 43.7 0.3 0.0031 17.6 0.0 7.3 9 0 0 9 9 8 2 HEAT repeat Adaptin_N PF01602.20 OWF46849.1 - 1.2e-06 27.4 0.0 3.5e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 OWF46849.1 - 1.8e-05 24.8 0.2 0.076 13.1 0.4 3.5 3 1 1 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 OWF46849.1 - 0.0011 18.5 0.2 13 5.1 0.4 3.3 2 1 1 3 3 3 1 Armadillo-like RICTOR_V PF14668.6 OWF46849.1 - 0.0023 18.1 0.2 6.3 7.1 0.0 4.8 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Fibritin_C PF07921.12 OWF46849.1 - 0.026 14.6 2.0 0.58 10.3 0.3 3.6 3 1 1 4 4 4 0 Fibritin C-terminal region IFRD PF05004.13 OWF46849.1 - 0.06 12.4 0.0 0.97 8.5 0.0 2.6 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 OWF46849.1 - 0.14 12.2 1.6 1.4 9.0 0.8 2.8 2 1 1 3 3 3 0 Parkin co-regulated protein FOP_dimer PF09398.10 OWF46850.1 - 2.6e-22 78.8 0.0 6.1e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 FOP N terminal dimerisation domain EF-hand_6 PF13405.6 OWF46850.1 - 1.8e-05 24.3 1.1 1.8e-05 24.3 1.1 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OWF46850.1 - 2.1e-05 24.9 7.1 2.1e-05 24.9 7.1 2.9 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF46850.1 - 9.9e-05 21.6 2.1 9.9e-05 21.6 2.1 3.6 3 0 0 3 3 3 2 EF hand LisH_2 PF16045.5 OWF46850.1 - 0.00046 19.1 0.0 0.00084 18.3 0.0 1.5 1 0 0 1 1 1 1 LisH EF-hand_5 PF13202.6 OWF46850.1 - 0.00094 18.6 0.8 0.00094 18.6 0.8 3.2 3 0 0 3 3 3 1 EF hand Cofac_haem_bdg PF04187.13 OWF46850.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Pkinase_Tyr PF07714.17 OWF46851.1 - 2e-59 201.0 0.0 3.3e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF46851.1 - 4.6e-55 186.8 0.0 8.7e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OWF46851.1 - 0.0023 17.9 0.0 0.19 11.6 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kelch_1 PF01344.25 OWF46852.1 - 3.3e-76 250.6 10.8 1.9e-14 53.0 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF46852.1 - 7.9e-46 152.9 7.7 1.3e-08 34.8 0.1 6.5 3 1 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 OWF46852.1 - 3.1e-31 106.1 4.2 5.3e-06 26.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 OWF46852.1 - 1.9e-28 98.9 0.1 5.7e-28 97.4 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF46852.1 - 5.8e-28 97.0 0.1 1.1e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 OWF46852.1 - 3.2e-24 84.7 10.1 0.00014 22.0 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF46852.1 - 6.7e-22 77.2 6.2 0.00033 20.6 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF46852.1 - 2.5e-15 56.1 4.3 0.00026 20.9 0.2 6.4 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 OWF46852.1 - 0.17 12.1 1.0 0.65 10.2 0.1 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3342) Neur_chan_LBD PF02931.23 OWF46853.1 - 1.2e-45 155.6 2.4 1.7e-45 155.1 2.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF46853.1 - 4.1e-20 72.9 0.9 5.6e-20 72.4 0.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_2 PF13903.6 OWF46853.1 - 0.034 13.9 4.2 0.098 12.4 0.1 2.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Glycos_transf_2 PF00535.26 OWF46856.1 - 3.5e-23 82.2 0.0 7e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 OWF46856.1 - 9.7e-10 38.0 0.0 2.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF46856.1 - 8.6e-06 25.8 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OWF46856.1 - 5.2e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF46857.1 - 1.7e-26 93.0 0.0 3.3e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 OWF46857.1 - 2.6e-10 39.8 0.0 5.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF46857.1 - 1.5e-07 31.5 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OWF46857.1 - 3.1e-06 26.9 0.0 7.4e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OWF46857.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OWF46857.1 - 0.009 15.5 0.0 0.036 13.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 WD40 PF00400.32 OWF46858.1 - 1.1e-15 57.7 17.9 3.4e-05 24.5 0.0 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46858.1 - 0.0047 17.2 0.0 5.4 7.4 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OWF46858.1 - 0.019 15.4 0.1 23 5.7 0.1 4.3 4 0 0 4 4 4 0 PQQ-like domain DUF1664 PF07889.12 OWF46860.1 - 0.00013 22.0 9.5 0.0029 17.7 0.9 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 OWF46860.1 - 0.00077 19.6 0.4 0.027 14.6 0.0 2.9 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 OWF46860.1 - 0.0015 18.6 7.5 0.031 14.3 2.0 3.0 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 OWF46860.1 - 0.0029 17.5 0.2 0.026 14.4 0.0 2.4 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 OWF46860.1 - 0.014 15.0 2.3 0.03 13.9 0.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1016_N PF17761.1 OWF46860.1 - 0.023 14.9 0.1 0.055 13.6 0.1 1.7 1 0 0 1 1 1 0 DUF1016 N-terminal domain Mce4_CUP1 PF11887.8 OWF46860.1 - 0.029 13.8 0.4 0.059 12.8 0.4 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative KxDL PF10241.9 OWF46860.1 - 0.053 13.8 4.7 0.12 12.7 0.8 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Kinesin_assoc PF16183.5 OWF46860.1 - 0.15 12.2 0.5 0.53 10.4 0.5 1.9 1 1 0 1 1 1 0 Kinesin-associated EspB PF05802.11 OWF46860.1 - 0.35 10.8 4.3 9.7 6.1 1.0 2.5 3 0 0 3 3 2 0 Enterobacterial EspB protein DASH_Dam1 PF08653.10 OWF46860.1 - 0.43 10.4 11.0 2.7 7.9 0.1 4.1 3 1 0 3 3 3 0 DASH complex subunit Dam1 AI-2E_transport PF01594.16 OWF46860.1 - 0.49 9.5 5.4 0.24 10.5 2.0 2.1 2 1 1 3 3 3 0 AI-2E family transporter DUF2205 PF10224.9 OWF46860.1 - 0.56 10.2 4.7 3.6 7.7 0.3 3.3 3 1 0 3 3 3 0 Short coiled-coil protein Muted PF14942.6 OWF46860.1 - 0.64 10.4 8.6 1.1 9.5 0.4 3.1 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Rogdi_lz PF10259.9 OWF46860.1 - 0.99 8.8 5.5 7.4 5.9 0.1 2.4 2 1 0 2 2 2 0 Rogdi leucine zipper containing protein DUF4456 PF14644.6 OWF46860.1 - 1.3 8.7 11.4 0.075 12.7 1.6 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4456) Vps51 PF08700.11 OWF46860.1 - 2.6 8.2 9.2 2.7 8.1 0.0 4.0 3 1 0 4 4 4 0 Vps51/Vps67 FliD_N PF02465.18 OWF46860.1 - 5.6 7.7 9.6 21 5.9 0.1 3.3 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Wtap PF17098.5 OWF46860.1 - 6.3 6.7 9.5 5.4 6.9 0.2 3.0 2 1 0 2 2 2 0 WTAP/Mum2p family DUF2884 PF11101.8 OWF46860.1 - 8.9 5.7 17.1 3.2 7.2 10.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2884) DUF5082 PF16888.5 OWF46860.1 - 9.5 6.5 7.9 4.5 7.6 1.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) HR1 PF02185.16 OWF46860.1 - 9.6 6.4 7.2 0.74 10.0 0.4 2.4 2 1 0 2 2 2 0 Hr1 repeat Sulfotransfer_1 PF00685.27 OWF46861.1 - 5.4e-40 137.6 2.4 1.5e-37 129.6 2.4 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF46861.1 - 5.8e-05 23.6 0.1 0.0004 20.8 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Aminotran_5 PF00266.19 OWF46862.1 - 7.2e-21 74.6 0.0 2.7e-20 72.7 0.0 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OWF46862.1 - 1.2e-06 28.0 0.1 1.7e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OWF46862.1 - 1.5e-05 23.7 0.1 2e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 OWF46862.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OWF46863.1 - 7.5e-23 81.1 0.0 3.7e-22 78.8 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OWF46863.1 - 5e-06 25.9 0.0 7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OWF46863.1 - 3.6e-05 23.2 0.5 5.8e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OWF46863.1 - 0.00025 19.7 0.2 0.00038 19.1 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 OWF46863.1 - 0.0015 17.4 0.3 0.0024 16.7 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 OWF46863.1 - 0.035 12.8 0.0 0.067 11.9 0.0 1.5 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF4806 PF16064.5 OWF46863.1 - 0.079 13.3 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) A_thal_3526 PF09713.10 OWF46863.1 - 0.4 11.0 1.5 11 6.4 0.1 3.0 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) 5_nucleotid_C PF02872.18 OWF46864.1 - 1.2e-43 149.1 0.0 2.6e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OWF46864.1 - 6.9e-13 49.6 0.0 1.4e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Myticin-prepro PF10690.9 OWF46865.1 - 0.088 13.1 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DUF2846 PF11008.8 OWF46865.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Ank_2 PF12796.7 OWF46866.1 - 1.4e-07 32.0 0.6 0.62 10.7 0.0 4.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF46866.1 - 2.8e-07 30.3 6.4 3.4 8.5 0.0 7.1 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 OWF46866.1 - 1.9e-05 25.1 1.5 19 6.0 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF46866.1 - 0.041 14.3 13.8 1 9.9 0.0 5.3 7 0 0 7 7 7 0 Ankyrin repeat RsbU_N PF08673.10 OWF46866.1 - 0.05 13.7 0.1 0.16 12.1 0.1 1.9 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain EGF_2 PF07974.13 OWF46867.1 - 0.1 13.0 196.4 1.2 9.6 6.1 14.3 12 6 0 12 12 12 0 EGF-like domain Membrane_bind PF14564.6 OWF46867.1 - 1.7 9.1 8.6 75 3.8 0.0 5.1 1 1 6 8 8 8 0 Membrane binding RdRP PF05183.12 OWF46868.1 - 1.3e-171 572.2 0.1 1.8e-171 571.8 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Suf PF05843.14 OWF46868.1 - 0.95 9.4 7.4 1.9 8.4 7.4 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AP3D1 PF06375.11 OWF46868.1 - 2.6 8.3 11.6 2.3 8.4 9.7 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 MSA_2 PF00985.17 OWF46868.1 - 2.7 8.3 10.7 4.9 7.5 10.7 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family RdRP PF05183.12 OWF46869.1 - 4.1e-65 220.6 0.0 5.9e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Suf PF05843.14 OWF46869.1 - 1.6 8.6 7.1 3.1 7.7 7.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RdRP PF05183.12 OWF46870.1 - 1.5e-85 288.0 0.2 3.3e-85 286.9 0.2 1.5 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 OWF46871.1 - 3.6e-174 580.7 0.0 6.1e-174 579.9 0.0 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 OWF46872.1 - 3.9e-174 580.6 0.0 6.1e-174 579.9 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Glyco_transf_10 PF00852.19 OWF46873.1 - 6e-41 140.1 5.9 6e-41 140.1 5.9 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF46873.1 - 8.9e-22 77.7 7.4 4.1e-21 75.5 2.9 2.6 2 0 0 2 2 2 2 Fucosyltransferase, N-terminal WD40 PF00400.32 OWF46874.1 - 9.8e-14 51.5 9.5 3.1e-05 24.6 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 OWF46874.1 - 0.00038 19.2 0.2 0.0012 17.6 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Dopey_N PF04118.14 OWF46875.1 - 3.1e-105 351.7 0.0 1.6e-104 349.3 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal OapA_N PF08525.11 OWF46875.1 - 0.11 12.4 0.2 0.34 10.9 0.2 1.9 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif zf-Tim10_DDP PF02953.15 OWF46876.1 - 6.2e-24 83.4 2.1 7.1e-24 83.2 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TIL PF01826.17 OWF46876.1 - 0.016 15.4 0.6 0.022 15.0 0.6 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Globin PF00042.22 OWF46877.1 - 4.8e-15 56.1 0.1 6.4e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Globin Ig_3 PF13927.6 OWF46878.1 - 0.03 14.9 0.1 0.31 11.7 0.0 2.8 2 1 0 2 2 2 0 Immunoglobulin domain EzrA PF06160.12 OWF46878.1 - 0.03 12.5 0.3 0.044 11.9 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2373 PF10180.9 OWF46879.1 - 0.044 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF3678 PF12435.8 OWF46879.1 - 2.8 7.4 8.7 2.1 7.8 6.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3678) Pyridoxal_deC PF00282.19 OWF46880.1 - 3.6e-105 351.8 0.0 4.2e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OWF46880.1 - 4.2e-06 25.9 0.0 6.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OWF46880.1 - 4.5e-05 22.9 0.0 6.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 OWF46880.1 - 0.0047 15.7 0.0 0.0078 14.9 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF1674 PF07896.12 OWF46881.1 - 4.5e-09 36.7 7.1 3.3e-08 33.9 7.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) MIF4G_like_2 PF09090.11 OWF46882.1 - 1.4e-33 116.5 0.9 2.2e-33 115.9 0.9 1.2 1 0 0 1 1 1 1 MIF4G like Trimer_CC PF08954.11 OWF46882.1 - 0.039 13.5 2.8 0.19 11.3 0.8 2.4 2 0 0 2 2 2 0 Trimerisation motif Atg14 PF10186.9 OWF46882.1 - 0.055 12.6 0.7 0.077 12.1 0.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 OWF46882.1 - 0.096 12.7 3.5 0.25 11.4 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 OWF46882.1 - 0.17 12.0 2.6 13 5.9 0.6 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Ax_dynein_light PF10211.9 OWF46882.1 - 0.26 11.2 4.6 0.41 10.6 4.6 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain CLZ PF16526.5 OWF46882.1 - 0.57 10.6 5.7 9 6.7 0.9 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Siah-Interact_N PF09032.11 OWF46882.1 - 1.1 9.6 5.7 2.2 8.6 5.7 1.6 1 1 0 1 1 1 0 Siah interacting protein, N terminal XhlA PF10779.9 OWF46882.1 - 3.7 7.8 5.2 8 6.8 2.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA MIF4G_like PF09088.11 OWF46883.1 - 1.2e-37 129.6 0.5 4.9e-36 124.3 0.2 2.5 1 1 1 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 OWF46883.1 - 2e-31 109.4 0.2 6.4e-31 107.8 0.0 1.9 3 0 0 3 3 3 1 MIF4G like MIF4G PF02854.19 OWF46883.1 - 1.1e-19 71.0 0.3 2.8e-19 69.6 0.1 1.9 2 0 0 2 2 2 1 MIF4G domain DUF4573 PF15140.6 OWF46884.1 - 5.3e-07 29.6 16.4 0.0012 18.6 5.0 4.1 1 1 2 4 4 4 4 Domain of unknown function (DUF4573) MutS_V PF00488.21 OWF46885.1 - 1.5e-68 230.5 0.2 3.4e-68 229.4 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OWF46885.1 - 2e-35 122.7 0.6 2e-35 122.7 0.6 3.1 3 1 0 3 3 3 1 MutS domain III MutS_I PF01624.20 OWF46885.1 - 7.8e-29 100.2 0.0 1.8e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OWF46885.1 - 2.9e-16 60.0 0.0 9.1e-16 58.4 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OWF46885.1 - 4.3e-07 30.2 0.0 1.4e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV DUF1241 PF06840.11 OWF46885.1 - 0.082 12.6 0.1 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) MIB_HERC2 PF06701.13 OWF46886.1 - 1.1e-09 38.4 9.6 1.1e-05 25.6 2.2 2.7 2 0 0 2 2 2 2 Mib_herc2 WWE PF02825.20 OWF46886.1 - 3.2e-09 37.2 0.1 1.1e-08 35.6 0.1 2.0 1 0 0 1 1 1 1 WWE domain VWA_2 PF13519.6 OWF46886.1 - 1.7e-08 35.0 0.2 1.1e-07 32.5 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain Vps53_N PF04100.12 OWF46886.1 - 0.011 14.7 0.7 0.017 14.1 0.7 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal COOH-NH2_lig PF14395.6 OWF46886.1 - 0.044 13.0 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF5641 PF18701.1 OWF46886.1 - 0.11 12.6 0.7 0.69 10.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Noelin-1 PF12308.8 OWF46886.1 - 0.12 12.3 0.8 0.34 10.9 0.8 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein Spc7 PF08317.11 OWF46886.1 - 0.14 11.0 1.6 0.25 10.2 1.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 OWF46886.1 - 1.1 9.5 6.3 0.85 9.9 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF948 PF06103.11 OWF46886.1 - 7.2 6.9 9.3 6.7 7.0 0.3 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MIB_HERC2 PF06701.13 OWF46887.1 - 5.1e-30 103.5 23.3 9.5e-18 64.2 2.6 3.3 3 0 0 3 3 3 2 Mib_herc2 VWA_2 PF13519.6 OWF46887.1 - 1.3e-13 51.5 0.0 1.3e-12 48.3 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OWF46887.1 - 5.6e-10 39.7 0.0 2.1e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain WWE PF02825.20 OWF46887.1 - 9.7e-08 32.5 2.1 9.7e-08 32.5 2.1 2.4 2 0 0 2 2 2 1 WWE domain DUF4314 PF14192.6 OWF46887.1 - 0.0015 18.4 6.0 0.03 14.2 0.2 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4314) bMG6 PF17962.1 OWF46887.1 - 1 9.6 7.6 0.2 11.8 2.0 2.7 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 TIR_2 PF13676.6 OWF46888.1 - 3.1e-12 47.1 0.1 2.2e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 TIR domain RNR_Alpha PF17975.1 OWF46888.1 - 0.017 15.6 0.1 0.19 12.2 0.1 2.8 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain DUF4239 PF14023.6 OWF46889.1 - 0.0032 17.2 1.5 0.18 11.5 0.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4239) DUF3911 PF13050.6 OWF46889.1 - 0.018 15.1 0.3 0.052 13.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) TFB6 PF17110.5 OWF46889.1 - 0.061 13.1 0.2 0.77 9.5 0.1 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH T4_deiodinase PF00837.17 OWF46890.1 - 6.2e-13 48.6 0.0 6.2e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase CENP-P PF13096.6 OWF46890.1 - 0.034 13.8 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P T4_deiodinase PF00837.17 OWF46891.1 - 4.2e-43 147.4 0.0 4.6e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase EF-hand_7 PF13499.6 OWF46892.1 - 3.5e-12 46.6 9.0 2.6e-09 37.4 3.8 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF46892.1 - 1.9e-08 33.6 8.1 0.0022 17.8 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OWF46892.1 - 3.3e-07 29.4 10.4 0.067 12.8 0.1 4.0 4 0 0 4 4 4 3 EF hand Caprin-1_dimer PF18293.1 OWF46892.1 - 0.042 14.3 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 Caprin-1 dimerization domain EF-hand_8 PF13833.6 OWF46892.1 - 1 9.2 11.6 0.53 10.2 1.9 3.1 1 1 2 3 3 3 0 EF-hand domain pair PI3Ka PF00613.20 OWF46893.1 - 5.5e-57 192.2 1.4 1.1e-56 191.2 1.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OWF46893.1 - 2.8e-50 171.5 0.0 1.7e-35 123.0 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OWF46893.1 - 2.4e-46 157.1 0.0 4.3e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 BUD22 PF09073.10 OWF46894.1 - 1.8e-09 37.5 9.9 1.8e-09 37.5 9.9 3.6 1 1 1 2 2 2 1 BUD22 Mlf1IP PF10248.9 OWF46895.1 - 2.2e-09 37.5 14.1 2.3e-08 34.2 13.3 2.1 1 1 1 2 2 2 2 Myelodysplasia-myeloid leukemia factor 1-interacting protein Retrotrans_gag PF03732.17 OWF46896.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein BTB_2 PF02214.22 OWF46897.1 - 1.8e-15 57.1 0.0 5.2e-15 55.6 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 OWF46897.1 - 0.0012 18.9 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF46897.1 - 0.028 14.6 0.0 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Abhydrolase_1 PF00561.20 OWF46898.1 - 3.2e-23 82.7 0.3 6.8e-22 78.4 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF46898.1 - 3e-22 80.3 0.0 3.7e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF46898.1 - 2.5e-11 43.3 0.0 7.9e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OWF46898.1 - 1e-07 30.9 0.0 5.7e-07 28.5 0.0 1.9 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.13 OWF46898.1 - 0.0028 17.4 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 OWF46898.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Cohesin_load PF10345.9 OWF46899.1 - 6.7e-116 388.1 23.9 7.6e-116 387.9 23.9 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 OWF46899.1 - 2.5e-11 43.7 14.4 0.00083 19.6 1.3 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46899.1 - 1.7e-08 34.0 6.6 2.9 8.3 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF46899.1 - 3.1e-07 30.1 22.7 0.00077 18.9 4.9 3.3 2 2 0 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 OWF46899.1 - 2.1e-06 27.4 9.5 4.9 7.5 0.4 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46899.1 - 4.1e-05 23.2 5.4 17 5.4 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46899.1 - 0.00013 21.7 6.7 0.11 12.5 0.4 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 OWF46899.1 - 0.00015 21.6 4.3 0.046 13.4 0.3 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 OWF46899.1 - 0.00092 19.7 4.3 0.14 12.7 0.5 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat HemY_N PF07219.13 OWF46899.1 - 0.019 15.2 0.7 2.3 8.4 0.0 3.6 4 0 0 4 4 4 0 HemY protein N-terminus TPR_7 PF13176.6 OWF46899.1 - 0.036 14.1 8.1 23 5.3 0.0 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 OWF46899.1 - 0.065 12.9 1.5 11 5.8 0.0 4.0 5 0 0 5 5 5 0 TPR repeat AMP-binding PF00501.28 OWF46899.1 - 0.12 11.0 0.5 0.19 10.3 0.5 1.3 1 0 0 1 1 1 0 AMP-binding enzyme HTH_30 PF13556.6 OWF46900.1 - 4.2e-08 32.9 6.2 5.5 6.9 0.0 8.0 6 3 2 8 8 8 2 PucR C-terminal helix-turn-helix domain DUF4121 PF13497.6 OWF46900.1 - 0.024 13.8 0.0 38 3.3 0.0 4.4 1 1 3 5 5 5 0 Domain of unknown function (DUF4121) HTH_3 PF01381.22 OWF46900.1 - 0.1 12.7 9.3 13 5.9 0.1 6.4 5 1 3 8 8 8 0 Helix-turn-helix ROQ_II PF18386.1 OWF46900.1 - 0.16 11.8 0.1 63 3.5 0.0 3.8 2 1 2 4 4 4 0 Roquin II domain Imm6 PF14434.6 OWF46900.1 - 0.21 11.5 6.3 25 4.8 0.1 4.4 4 2 1 5 5 5 0 Immunity protein Imm6 DUF4559 PF15112.6 OWF46900.1 - 0.66 9.6 7.3 9.7 5.8 0.6 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4559) E3_UbLigase_EDD PF11547.8 OWF46900.1 - 1 9.1 11.6 43 3.9 0.1 5.6 5 0 0 5 5 5 0 E3 ubiquitin ligase EDD SPATA24 PF15175.6 OWF46900.1 - 1.3 8.9 12.2 2.2 8.1 0.2 3.9 2 2 0 3 3 3 0 Spermatogenesis-associated protein 24 Jnk-SapK_ap_N PF09744.9 OWF46900.1 - 2.4 8.4 21.0 5 7.3 2.8 4.2 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Rx_N PF18052.1 OWF46900.1 - 5.7 7.3 27.3 1.9 8.8 0.4 6.5 3 2 2 8 8 8 0 Rx N-terminal domain Alkyl_sulf_C PF14864.6 OWF46900.1 - 7 6.9 6.0 51 4.2 0.2 4.2 4 2 1 5 5 5 0 Alkyl sulfatase C-terminal P66_CC PF16563.5 OWF46901.1 - 1.4e-10 40.6 5.6 2.7e-10 39.7 5.6 1.5 1 0 0 1 1 1 1 Coiled-coil and interaction region of P66A and P66B with MBD2 HECT PF00632.25 OWF46902.1 - 2.2e-98 329.5 0.1 3e-98 329.1 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OWF46902.1 - 3.4e-51 171.0 17.2 4.4e-13 49.1 1.5 4.9 4 0 0 4 4 4 4 WW domain C2 PF00168.30 OWF46902.1 - 6.9e-23 80.9 0.0 1.5e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain AMP-binding PF00501.28 OWF46903.1 - 3.5e-56 190.6 0.0 4.6e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF46903.1 - 4.7e-05 24.3 0.0 0.00015 22.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain OCRE PF17780.1 OWF46904.1 - 0.32 11.1 24.6 92 3.2 0.7 6.4 1 1 2 3 3 3 0 OCRE domain DUF1031 PF06275.11 OWF46904.1 - 0.34 11.2 7.6 48 4.3 0.1 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1031) Arg_decarb_HB PF17810.1 OWF46904.1 - 1.3 9.3 5.2 7.9 6.8 0.2 3.5 1 1 2 3 3 3 0 Arginine decarboxylase helical bundle domain UBA PF00627.31 OWF46908.1 - 0.0034 17.2 0.0 0.12 12.3 0.0 3.0 3 0 0 3 3 3 1 UBA/TS-N domain UBA_3 PF09288.10 OWF46908.1 - 0.04 13.7 0.1 2 8.3 0.0 2.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF5401 PF17380.2 OWF46908.1 - 0.22 9.6 6.6 0.34 8.9 6.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF2464 PF10240.9 OWF46908.1 - 0.23 11.0 0.0 0.23 11.0 0.0 2.4 2 1 0 2 2 2 0 Multivesicular body subunit 12 WRNPLPNID PF15017.6 OWF46908.1 - 9.7 7.2 12.2 19 6.2 0.2 3.6 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box 7tm_1 PF00001.21 OWF46909.1 - 2.1e-12 46.9 14.4 3.6e-12 46.2 14.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF898 PF05987.13 OWF46909.1 - 0.0042 16.2 5.1 0.0057 15.8 5.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF1772 PF08592.11 OWF46909.1 - 0.23 11.8 5.5 1 9.7 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) PG_isomerase_N PF18353.1 OWF46910.1 - 0.0023 18.3 0.4 1.8 9.0 0.4 3.0 1 1 0 1 1 1 1 Phosphoglucose isomerase N-terminal domain Cornifin PF02389.15 OWF46910.1 - 0.034 14.3 0.0 0.53 10.5 0.0 1.8 1 1 0 1 1 1 0 Cornifin (SPRR) family Kinesin PF00225.23 OWF46911.1 - 5e-97 324.8 1.0 9.3e-97 323.9 1.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF46911.1 - 4.8e-18 65.5 0.0 9.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_2 PF07647.17 OWF46911.1 - 0.00086 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF46911.1 - 0.091 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NUDIX PF00293.28 OWF46912.1 - 6.9e-21 74.7 0.0 8.8e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Pro_isomerase PF00160.21 OWF46913.1 - 2.9e-40 138.1 0.2 3.8e-40 137.7 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD KH_1 PF00013.29 OWF46914.1 - 0.1 12.5 0.0 0.74 9.7 0.0 2.4 3 0 0 3 3 3 0 KH domain Rav1p_C PF12234.8 OWF46915.1 - 7.4e-82 275.8 8.8 1.2e-64 218.9 1.9 4.2 3 1 1 4 4 4 4 RAVE protein 1 C terminal WD40 PF00400.32 OWF46915.1 - 5e-19 68.3 20.9 0.00021 22.0 0.0 11.5 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF46915.1 - 0.00092 19.5 0.0 0.36 11.2 0.0 4.7 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain LCD1 PF09798.9 OWF46915.1 - 0.5 8.8 3.4 0.16 10.5 0.0 1.7 2 0 0 2 2 2 0 DNA damage checkpoint protein C2 PF00168.30 OWF46916.1 - 2.2e-34 117.8 0.1 6.9e-20 71.3 0.1 2.4 2 0 0 2 2 2 2 C2 domain PorB PF11565.8 OWF46916.1 - 0.019 15.3 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 Alpha helical Porin B NT-C2 PF10358.9 OWF46916.1 - 0.032 14.0 0.3 1.4 8.6 0.0 2.5 1 1 1 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins CEP76-C2 PF15627.6 OWF46916.1 - 0.038 13.5 0.0 0.94 9.0 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain DpaA_N PF16924.5 OWF46917.1 - 0.04 14.0 1.1 0.71 10.0 0.0 2.6 2 1 1 3 3 3 0 Dipicolinate synthase subunit A N-terminal domain RACo_linker PF17650.1 OWF46918.1 - 0.00031 20.5 3.2 17 5.3 0.1 4.9 1 1 6 7 7 7 2 RACo linker region DUF402 PF04167.13 OWF46918.1 - 0.0036 17.5 14.9 4.4 7.6 0.4 4.4 1 1 2 3 3 3 3 Protein of unknown function (DUF402) Fungal_trans PF04082.18 OWF46918.1 - 0.68 8.9 4.9 27 3.6 0.8 3.8 1 1 2 3 3 3 0 Fungal specific transcription factor domain Phage_Arf PF17585.2 OWF46918.1 - 1.5 8.9 8.0 17 5.5 0.2 4.7 2 2 3 6 6 6 0 Accessory recombination function protein Trm5_N PF18093.1 OWF46919.1 - 1.6e-06 27.9 0.4 18 5.3 0.0 6.8 8 2 1 9 9 9 3 tRNA methyltransferase 5 N-terminal domain Acetyltransf_19 PF18015.1 OWF46919.1 - 0.019 15.2 5.9 17 5.7 0.0 5.1 3 2 4 7 7 7 0 Acetyltransferase (GNAT) domain Oxidored_q6 PF01058.22 OWF46919.1 - 0.064 13.1 1.1 78 3.1 0.1 4.9 3 1 2 6 6 6 0 NADH ubiquinone oxidoreductase, 20 Kd subunit zinc_ribbon_9 PF14369.6 OWF46919.1 - 0.64 10.3 16.1 69 3.8 0.2 6.5 3 2 3 6 6 6 0 zinc-ribbon OLF PF02191.16 OWF46920.1 - 2.5e-54 184.4 4.8 3.1e-54 184.1 4.8 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 OWF46920.1 - 5.5e-36 122.1 134.4 3.7e-09 36.2 23.2 5.4 2 1 3 5 5 5 5 Collagen triple helix repeat (20 copies) Mucin PF01456.17 OWF46920.1 - 0.41 10.6 20.5 0.76 9.8 20.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.8 OWF46920.1 - 1.6 7.9 8.7 2.6 7.2 8.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PH PF00169.29 OWF46921.1 - 0.00011 22.6 1.9 0.00021 21.8 1.9 1.5 1 0 0 1 1 1 1 PH domain Glyco_hydro_57 PF03065.15 OWF46921.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 APC_r PF05923.12 OWF46922.1 - 5 7.0 13.4 15 5.4 0.0 5.7 6 1 0 6 6 6 0 APC repeat KxDL PF10241.9 OWF46923.1 - 0.00038 20.7 6.9 0.00038 20.7 6.9 11.0 7 3 3 10 10 10 1 Uncharacterized conserved protein DUF4201 PF13870.6 OWF46923.1 - 0.00096 18.9 13.5 0.00096 18.9 13.5 9.6 6 2 3 10 10 10 2 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.11 OWF46923.1 - 0.0025 17.7 5.1 0.0025 17.7 5.1 7.8 7 3 1 9 9 9 2 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.21 OWF46923.1 - 0.0044 16.7 3.2 0.0044 16.7 3.2 6.9 4 2 1 6 6 6 4 Intermediate filament protein GP57 PF17594.2 OWF46923.1 - 0.013 15.2 0.2 0.15 11.8 0.1 2.8 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 Bap31_Bap29_C PF18035.1 OWF46923.1 - 0.014 15.4 1.5 0.014 15.4 1.5 10.1 9 3 4 13 13 13 0 Bap31/Bap29 cytoplasmic coiled-coil domain RT_RNaseH_2 PF17919.1 OWF46923.1 - 0.092 12.8 4.1 9 6.4 0.1 4.2 2 1 1 3 3 3 0 RNase H-like domain found in reverse transcriptase DAO PF01266.24 OWF46924.1 - 3.2e-29 102.6 0.0 4e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF46924.1 - 0.017 14.4 0.3 0.024 13.9 0.3 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 OWF46924.1 - 0.023 13.8 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 OWF46924.1 - 0.071 12.4 0.3 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OWF46924.1 - 0.082 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase_Tyr PF07714.17 OWF46925.1 - 8.5e-94 313.6 0.0 1.4e-93 313.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 OWF46925.1 - 1.3e-47 160.6 2.1 1.4e-22 79.9 1.1 2.8 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 OWF46925.1 - 2.1e-40 138.7 0.0 4e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 OWF46925.1 - 9.1e-21 74.3 31.2 9.1e-21 74.3 31.2 2.4 2 0 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.21 OWF46925.1 - 5.4e-19 68.3 5.0 2.7e-07 30.8 0.2 4.9 4 0 0 4 4 4 3 Fibronectin type III domain Kinase-like PF14531.6 OWF46925.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YAF2_RYBP PF17219.3 OWF46926.1 - 0.0072 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif Arrestin_C PF02752.22 OWF46928.1 - 2.9e-18 66.6 1.2 7.3e-17 62.1 0.1 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF46928.1 - 4.1e-18 65.8 0.6 2.6e-13 50.3 0.0 3.2 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain MG2 PF01835.19 OWF46928.1 - 0.048 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 MG2 domain DUF2393 PF09624.10 OWF46928.1 - 0.065 13.2 0.4 0.065 13.2 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Arrestin_C PF02752.22 OWF46929.1 - 9.6e-21 74.6 0.0 4e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF46929.1 - 4.4e-17 62.5 0.0 1.9e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OWF46929.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Rgp1 Ski_Sno PF02437.17 OWF46930.1 - 1e-37 128.2 1.2 2.1e-37 127.2 0.6 1.8 2 0 0 2 2 2 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 OWF46930.1 - 5.7e-33 113.0 2.3 5.7e-33 113.0 2.3 1.9 2 0 0 2 2 2 1 c-SKI Smad4 binding domain V_ATPase_I PF01496.19 OWF46931.1 - 0.00022 19.3 0.4 0.00087 17.3 0.4 1.8 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family CLZ PF16526.5 OWF46931.1 - 0.00033 21.0 8.1 0.024 15.0 0.2 4.0 4 0 0 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2205 PF10224.9 OWF46931.1 - 0.0034 17.3 3.0 0.97 9.5 0.1 3.3 3 0 0 3 3 3 1 Short coiled-coil protein CENP-F_leu_zip PF10473.9 OWF46931.1 - 0.0069 16.4 6.0 0.19 11.7 0.1 3.6 3 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 OWF46931.1 - 0.0097 15.4 1.2 0.018 14.6 0.3 1.9 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal YabA PF06156.13 OWF46931.1 - 0.011 16.3 7.1 0.82 10.3 0.3 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Golgin_A5 PF09787.9 OWF46931.1 - 0.012 15.1 1.3 0.015 14.8 0.6 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Nsp1_C PF05064.13 OWF46931.1 - 0.015 15.1 1.0 6.6 6.6 0.1 3.1 4 0 0 4 4 4 0 Nsp1-like C-terminal region DUF4618 PF15397.6 OWF46931.1 - 0.035 13.5 1.9 0.64 9.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) HSP90 PF00183.18 OWF46931.1 - 0.069 12.0 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF1664 PF07889.12 OWF46931.1 - 0.083 12.9 2.5 3.3 7.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 OWF46931.1 - 0.19 11.9 5.1 1.7 8.9 0.4 3.3 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 OWF46931.1 - 0.2 11.9 5.9 1.8 8.8 1.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) HH_signal PF01085.18 OWF46932.1 - 1.2e-10 41.3 0.0 4.1e-06 26.5 0.0 3.6 3 0 0 3 3 3 2 Hedgehog amino-terminal signalling domain Big_9 PF17963.1 OWF46933.1 - 2.9e-08 34.3 0.2 2.9e-08 34.3 0.2 5.0 5 0 0 5 5 5 1 Bacterial Ig domain Cadherin_5 PF17892.1 OWF46933.1 - 1.3e-06 28.3 1.2 5.8e-06 26.2 0.2 2.8 2 1 0 2 2 2 1 Cadherin-like domain Cadherin_4 PF17803.1 OWF46933.1 - 1.6e-06 28.6 4.9 9.5e-05 23.0 0.4 4.1 2 0 0 2 2 2 1 Bacterial cadherin-like domain PAN_1 PF00024.26 OWF46933.1 - 0.0003 20.7 0.3 0.0003 20.7 0.3 2.3 2 0 0 2 2 2 1 PAN domain fn3 PF00041.21 OWF46933.1 - 0.018 15.3 22.2 0.037 14.4 0.0 8.4 10 0 0 10 10 10 0 Fibronectin type III domain Gal_Lectin PF02140.18 OWF46934.1 - 9.3e-17 61.2 7.4 9.3e-17 61.2 7.4 2.7 2 0 0 2 2 2 1 Galactose binding lectin domain fn3 PF00041.21 OWF46934.1 - 0.0029 17.9 10.8 0.35 11.2 0.3 8.1 10 0 0 10 10 10 1 Fibronectin type III domain Big_3_3 PF13750.6 OWF46934.1 - 0.058 13.0 0.8 83 2.8 0.0 5.7 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) Thioredoxin PF00085.20 OWF46935.1 - 1e-66 221.4 0.0 5.1e-32 109.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OWF46935.1 - 1.3e-31 110.0 6.3 5e-24 85.2 6.7 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OWF46935.1 - 2.2e-08 34.5 5.2 0.00045 20.6 0.1 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 OWF46935.1 - 1.5e-07 31.4 0.6 0.34 10.8 0.0 3.4 2 1 1 3 3 3 3 AhpC/TSA family Thioredoxin_8 PF13905.6 OWF46935.1 - 3.8e-07 30.4 0.1 0.078 13.3 0.0 4.2 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 OWF46935.1 - 2.1e-05 24.6 0.0 0.04 14.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 OWF46935.1 - 2.6e-05 23.7 0.1 0.025 14.0 0.0 3.0 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 OWF46935.1 - 0.036 14.3 0.2 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin MMtag PF10159.9 OWF46935.1 - 0.042 14.1 0.2 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Multiple myeloma tumor-associated Thioredoxin_4 PF13462.6 OWF46935.1 - 0.082 13.1 3.1 2.4 8.3 0.0 3.7 3 1 0 4 4 4 0 Thioredoxin LD_cluster3 PF18180.1 OWF46935.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster3 family MBD_C PF14048.6 OWF46936.1 - 6.5e-30 103.7 0.2 1.1e-29 103.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 OWF46936.1 - 1.4e-26 92.4 0.4 2.8e-26 91.5 0.4 1.5 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 OWF46936.1 - 3.2e-23 81.2 0.2 4.4e-17 61.5 0.0 2.3 1 1 1 2 2 2 2 Methyl-CpG binding domain NapD PF03927.13 OWF46936.1 - 0.15 12.1 0.1 0.52 10.4 0.1 1.8 2 0 0 2 2 2 0 NapD protein TERB2 PF15101.6 OWF46937.1 - 9.2e-41 140.2 2.9 2.8e-35 122.2 1.4 2.0 1 1 1 2 2 2 2 Telomere-associated protein TERB2 TPR_12 PF13424.6 OWF46938.1 - 4.2e-36 123.1 15.2 4.5e-08 33.3 0.8 9.6 8 2 1 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 OWF46938.1 - 7.7e-28 94.3 22.5 2e-05 24.3 0.0 12.8 16 0 0 16 16 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46938.1 - 5e-27 92.6 34.2 1.5e-05 24.6 0.1 13.7 13 1 1 14 14 13 6 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46938.1 - 1e-13 50.6 9.8 0.025 14.4 0.0 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF46938.1 - 1.1e-13 51.6 1.4 0.015 15.9 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46938.1 - 3.5e-12 45.5 34.5 0.079 13.2 0.0 11.7 12 1 0 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46938.1 - 5.2e-12 44.9 20.1 0.058 13.5 0.0 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 OWF46938.1 - 1.7e-10 40.8 5.6 0.66 10.7 0.1 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46938.1 - 2e-10 40.6 4.2 0.18 12.7 0.0 8.6 8 1 2 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46938.1 - 2.6e-09 37.5 8.3 0.53 10.8 0.1 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF46938.1 - 1.5e-06 28.4 15.1 1 9.6 0.1 7.0 7 1 1 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 OWF46938.1 - 1e-05 25.5 11.3 0.035 14.2 0.1 7.5 8 0 0 8 8 8 1 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 OWF46938.1 - 0.0019 17.6 7.9 1.6 8.0 0.8 5.3 4 2 1 5 5 5 1 MalT-like TPR region ANAPC5 PF12862.7 OWF46938.1 - 0.0077 16.3 1.3 0.036 14.1 0.4 2.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 OWF46938.1 - 0.0087 16.4 0.1 56 4.5 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat DIOX_N PF14226.6 OWF46938.1 - 0.11 13.3 0.1 0.23 12.2 0.1 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Fis1_TPR_C PF14853.6 OWF46938.1 - 0.15 12.1 3.3 25 5.1 0.0 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat RIG-I_C PF18119.1 OWF46938.1 - 0.2 11.7 1.7 0.48 10.4 0.1 2.5 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain RPN7 PF10602.9 OWF46938.1 - 0.84 9.3 9.2 2.9 7.6 0.2 4.7 4 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_11 PF13414.6 OWF46938.1 - 1 9.1 20.2 3.1 7.6 0.1 7.0 9 1 0 9 9 8 0 TPR repeat Paf67 PF10255.9 OWF46938.1 - 2.8 6.9 9.9 4.8 6.1 0.0 3.6 4 1 1 5 5 5 0 RNA polymerase I-associated factor PAF67 Mad3_BUB1_I PF08311.12 OWF46938.1 - 3.1 7.8 5.4 15 5.6 0.0 4.1 4 0 0 4 4 3 0 Mad3/BUB1 homology region 1 SPO22 PF08631.10 OWF46938.1 - 3.3 7.1 10.6 23 4.4 0.0 5.1 6 1 1 7 7 7 0 Meiosis protein SPO22/ZIP4 like TIR_2 PF13676.6 OWF46940.1 - 0.0016 19.0 0.0 0.0043 17.6 0.0 1.8 1 0 0 1 1 1 1 TIR domain Aldedh PF00171.22 OWF46941.1 - 5.6e-137 457.0 0.1 6.5e-137 456.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 OWF46941.1 - 0.021 14.8 0.2 0.041 13.9 0.2 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated ORC2 PF04084.14 OWF46942.1 - 1.8e-97 326.2 1.8 2.5e-97 325.8 1.8 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PBP1_TM PF14812.6 OWF46942.1 - 1 9.8 8.0 0.11 12.8 2.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORC6 PF05460.13 OWF46942.1 - 1.2 8.4 9.0 1.9 7.6 9.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TPK_catalytic PF04263.16 OWF46943.1 - 9.6e-36 122.5 0.0 1.3e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OWF46943.1 - 4.2e-22 77.6 0.0 6.6e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TIR_2 PF13676.6 OWF46944.1 - 8.3e-22 78.0 0.0 1.8e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain Arm PF00514.23 OWF46944.1 - 0.0024 17.9 0.0 4.3 7.5 0.0 3.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat TIR PF01582.20 OWF46944.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 TIR domain PRTase_2 PF15609.6 OWF46944.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase Cu-oxidase_4 PF02578.15 OWF46945.1 - 4.8e-54 183.4 0.0 6.8e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Forkhead PF00250.18 OWF46946.1 - 7.7e-33 112.6 0.3 1.4e-32 111.7 0.3 1.5 1 0 0 1 1 1 1 Forkhead domain GnHR_trans PF12369.8 OWF46946.1 - 0.032 15.0 0.0 0.078 13.8 0.0 1.6 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region NTPase_I-T PF01931.18 OWF46947.1 - 3.7e-11 43.1 0.0 6.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF84 PRCC PF10253.9 OWF46948.1 - 2.4e-33 116.7 8.7 2.4e-33 116.7 8.7 3.3 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting FAM83 PF07894.12 OWF46948.1 - 0.056 13.0 0.4 0.098 12.2 0.4 1.4 1 0 0 1 1 1 0 FAM83 A-H MtN3_slv PF03083.16 OWF46949.1 - 6.5e-28 96.6 18.1 4.5e-14 52.2 4.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 OWF46949.1 - 3.3e-08 33.2 11.8 0.00028 20.6 0.3 3.7 3 1 1 4 4 4 2 PQ loop repeat LAB_N PF07578.11 OWF46949.1 - 0.0051 16.9 2.3 1.3 9.2 0.1 2.7 2 0 0 2 2 2 2 Lipid A Biosynthesis N-terminal domain TcpE PF12648.7 OWF46949.1 - 0.089 13.3 0.9 0.089 13.3 0.9 2.5 1 1 1 2 2 2 0 TcpE family Imp-YgjV PF10688.9 OWF46949.1 - 2.9 7.7 16.6 0.75 9.6 0.4 3.5 3 1 1 4 4 4 0 Bacterial inner membrane protein SMN PF06003.12 OWF46950.1 - 4e-63 213.1 4.1 5.1e-63 212.8 4.1 1.0 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 OWF46950.1 - 6.8e-05 22.9 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 Tudor domain DUF1764 PF08576.10 OWF46950.1 - 0.0086 16.9 4.9 0.0086 16.9 4.9 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Peptidase_S49_N PF08496.10 OWF46950.1 - 0.14 12.2 2.7 0.2 11.7 2.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tudor_2 PF18104.1 OWF46950.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain LRIF1 PF15741.5 OWF46950.1 - 0.19 10.3 3.6 0.27 9.7 3.6 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Phage_1_1 PF08200.11 OWF46950.1 - 0.29 11.6 11.6 0.62 10.5 11.6 1.6 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein LBR_tudor PF09465.10 OWF46950.1 - 0.62 9.9 3.5 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain G-patch PF01585.23 OWF46951.1 - 1.7e-12 47.0 5.4 4.3e-12 45.7 5.4 1.7 1 0 0 1 1 1 1 G-patch domain Surp PF01805.20 OWF46951.1 - 1.5e-09 37.7 0.2 3.5e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 Surp module G-patch_2 PF12656.7 OWF46951.1 - 0.00029 20.9 0.6 0.00029 20.9 0.6 2.0 2 0 0 2 2 2 1 G-patch domain FeS_assembly_P PF01883.19 OWF46953.1 - 1.9e-07 31.1 0.0 4.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein OTU PF02338.19 OWF46954.1 - 1.9e-22 80.1 0.0 5e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease zf-A20 PF01754.16 OWF46954.1 - 1.4e-09 37.7 22.3 7.1e-07 29.1 4.9 2.6 2 0 0 2 2 2 2 A20-like zinc finger TAP_C PF03943.13 OWF46954.1 - 0.003 17.2 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 OWF46954.1 - 0.028 14.2 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain 7tm_1 PF00001.21 OWF46955.1 - 1.8e-07 30.8 17.5 0.0002 20.8 17.5 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PTPLA PF04387.14 OWF46955.1 - 0.63 9.8 8.8 2.1 8.1 1.8 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA RNA_pol_Rpc82 PF05645.13 OWF46957.1 - 1.3e-23 84.0 0.1 7.8e-23 81.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 OWF46957.1 - 1.5e-17 63.4 8.9 2.3e-15 56.4 3.2 3.6 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 OWF46957.1 - 4.5e-07 29.7 2.2 0.00026 20.8 0.2 3.0 3 0 0 3 3 3 2 TFIIE alpha subunit UBA2_C PF16195.5 OWF46957.1 - 0.042 14.5 0.4 0.1 13.3 0.4 1.6 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus RRF PF01765.19 OWF46957.1 - 0.048 13.6 4.4 0.086 12.8 4.4 1.5 1 0 0 1 1 1 0 Ribosome recycling factor CtsR_C PF17727.1 OWF46957.1 - 0.086 13.0 0.7 1 9.5 0.1 2.7 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Antifungal_prot PF11402.8 OWF46958.1 - 0.00021 21.5 32.4 1.2 9.4 2.2 5.1 1 1 2 3 3 3 2 Antifungal protein Baculo_PEP_C PF04513.12 OWF46958.1 - 0.00073 19.6 0.1 0.028 14.4 0.1 2.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-TRAF PF02176.18 OWF46958.1 - 0.00088 19.9 27.8 1.8e+04 -11.6 27.8 5.3 1 1 0 1 1 1 0 TRAF-type zinc finger PSP1 PF04468.12 OWF46958.1 - 0.1 12.9 8.9 6.8 7.0 0.9 2.9 1 1 3 4 4 4 0 PSP1 C-terminal conserved region MSP1b PF03429.13 OWF46958.1 - 1 7.4 5.0 1.3 7.0 5.0 1.2 1 0 0 1 1 1 0 Major surface protein 1B Sina PF03145.16 OWF46958.1 - 1.7 8.5 18.5 22 4.9 4.2 3.6 1 1 3 4 4 4 0 Seven in absentia protein family Zn_clus PF00172.18 OWF46958.1 - 9.6 6.4 26.4 1.8e+04 -13.9 26.4 5.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ion_trans PF00520.31 OWF46959.1 - 6e-239 788.7 99.6 5.1e-66 222.4 16.6 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 OWF46959.1 - 1.6e-15 56.8 84.5 1.7e-05 23.7 6.6 9.5 6 4 3 9 9 9 8 Polycystin cation channel Na_trans_assoc PF06512.13 OWF46959.1 - 2.4e-07 31.3 16.3 2.4e-07 31.3 16.3 3.4 4 0 0 4 4 4 2 Sodium ion transport-associated GPHH PF16905.5 OWF46959.1 - 2.5e-06 27.1 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 OWF46959.1 - 0.036 13.9 0.5 0.094 12.6 0.5 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif tRNA-synt_2b PF00587.25 OWF46960.1 - 7.1e-35 120.6 0.0 1.2e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OWF46960.1 - 6.3e-20 71.1 0.3 1.1e-19 70.3 0.3 1.4 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 OWF46960.1 - 6.7e-16 58.1 0.2 4e-15 55.6 0.0 2.4 3 0 0 3 3 3 1 TGS domain tRNA_SAD PF07973.14 OWF46960.1 - 2e-12 47.0 0.0 4.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RET_CLD4 PF17813.1 OWF46961.1 - 0.92 9.8 21.5 14 6.0 0.2 5.3 2 2 1 3 3 3 0 RET Cadherin like domain 4 DUF5050 PF16472.5 OWF46961.1 - 0.94 8.7 37.6 0.43 9.8 15.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5050) ArgoMid PF16487.5 OWF46961.1 - 4.7 7.6 8.0 10 6.5 0.5 2.9 1 1 2 3 3 3 0 Mid domain of argonaute Hormone_recep PF00104.30 OWF46962.1 - 1.8e-28 99.5 6.6 3.3e-28 98.7 0.0 2.3 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF46962.1 - 3.2e-27 94.8 16.3 3.9e-27 94.5 14.4 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) CSN5_C PF18323.1 OWF46962.1 - 6.4 7.8 10.5 19 6.3 1.3 2.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF1043 PF06295.12 OWF46963.1 - 0.029 14.4 2.2 0.029 14.4 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Spc7 PF08317.11 OWF46963.1 - 0.56 9.0 29.0 0.19 10.6 21.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Cauli_AT PF03233.13 OWF46963.1 - 1.1 9.2 13.7 0.39 10.6 7.4 2.6 1 1 1 2 2 2 0 Aphid transmission protein FUSC PF04632.12 OWF46963.1 - 2.1 6.8 3.3 2.6 6.5 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 OWF46963.1 - 2.9 6.7 13.3 5.3 5.8 13.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein T2SSF PF00482.23 OWF46963.1 - 2.9 7.9 5.1 10 6.1 4.9 2.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Methyltransf_2 PF00891.18 OWF46964.1 - 1.3e-40 139.0 0.0 2.4e-40 138.1 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 OWF46964.1 - 4.6e-12 45.8 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.14 OWF46964.1 - 1.7e-05 24.4 0.0 4.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OWF46964.1 - 2.2e-05 25.1 0.0 5.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF46964.1 - 8.9e-05 23.2 0.0 0.00058 20.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF46964.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF46964.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OWF46964.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase FERM_C PF09380.10 OWF46965.1 - 3.9e-20 72.0 0.1 7.7e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 OWF46965.1 - 1.6e-16 60.8 0.5 5.8e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 FERM central domain FA PF08736.11 OWF46965.1 - 2.1e-13 50.1 5.7 2.1e-13 50.1 5.7 3.0 3 0 0 3 3 3 1 FERM adjacent (FA) FERM_N PF09379.10 OWF46965.1 - 1.5e-10 40.8 0.8 4.6e-10 39.3 0.2 2.0 2 0 0 2 2 2 1 FERM N-terminal domain SARAF PF06682.12 OWF46965.1 - 0.43 10.2 3.2 2.5 7.6 0.4 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SOCS_box PF07525.16 OWF46966.1 - 1e-07 32.2 1.3 2.2e-07 31.1 1.3 1.6 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 OWF46966.1 - 3.5e-07 30.7 2.7 6.3e-07 29.9 1.9 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF46966.1 - 0.00061 20.0 0.6 0.0014 18.9 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF46966.1 - 0.013 16.1 0.2 0.084 13.5 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF46966.1 - 0.099 13.3 2.0 6.6 7.6 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeat DUF1622 PF07784.11 OWF46966.1 - 0.16 11.9 0.0 24 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) ARF7EP_C PF14949.6 OWF46967.1 - 1.1e-35 122.4 9.6 1.1e-35 122.4 9.6 1.6 2 0 0 2 2 2 1 ARF7 effector protein C-terminus PRP3 PF08572.10 OWF46967.1 - 0.047 13.4 0.4 0.075 12.8 0.1 1.5 1 1 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) DUF3918 PF13056.6 OWF46967.1 - 0.14 11.8 1.1 0.25 11.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) MFS_1 PF07690.16 OWF46968.1 - 8.2e-33 113.8 22.1 2.8e-19 69.2 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF46968.1 - 1.1e-32 113.5 15.6 1.6e-32 113.0 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 OWF46968.1 - 1.5e-06 27.0 15.1 4.9e-05 22.1 4.5 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein PilO PF04350.13 OWF46969.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilO Kelch_1 PF01344.25 OWF46970.1 - 8e-50 166.2 4.6 4e-10 39.1 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OWF46970.1 - 2.1e-38 129.4 5.8 2.9e-09 36.9 0.0 6.6 2 1 4 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OWF46970.1 - 2e-31 107.7 1.7 4.2e-05 23.7 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain BACK PF07707.15 OWF46970.1 - 2.5e-23 82.1 0.1 5.6e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 OWF46970.1 - 2.6e-22 79.2 0.5 6e-22 78.0 0.5 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 OWF46970.1 - 1.4e-19 69.2 2.1 0.0038 17.2 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OWF46970.1 - 1.1e-18 67.0 0.3 0.052 13.6 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF46970.1 - 9.7e-11 41.4 0.5 0.00012 22.0 0.0 5.3 5 0 0 5 5 5 1 Kelch motif PQQ_3 PF13570.6 OWF46970.1 - 0.22 12.0 0.5 17 6.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Spaetzle PF16077.5 OWF46971.1 - 1.6e-08 35.0 0.7 2.3e-08 34.5 0.7 1.2 1 0 0 1 1 1 1 Spaetzle NGF PF00243.18 OWF46971.1 - 2.5e-06 27.7 1.3 3.9e-06 27.1 1.3 1.3 1 0 0 1 1 1 1 Nerve growth factor family Ribosomal_S8e PF01201.22 OWF46972.1 - 1.7e-48 164.2 6.3 1.7e-48 164.2 6.3 2.4 1 1 1 2 2 2 1 Ribosomal protein S8e Pannexin_like PF12534.8 OWF46972.1 - 6.2 5.8 6.5 9.3 5.2 6.5 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 BRCA2 PF00634.18 OWF46973.1 - 9.2e-104 338.8 108.2 7.9e-08 31.8 0.2 23.5 22 3 1 23 23 23 20 BRCA2 repeat BRCA-2_helical PF09169.10 OWF46973.1 - 6.5e-42 143.3 0.0 2.7e-41 141.3 0.0 2.2 1 0 0 1 1 1 1 BRCA2, helical BRCA-2_OB1 PF09103.10 OWF46973.1 - 2.7e-41 140.4 0.0 2e-40 137.6 0.0 2.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 PF09104.10 OWF46973.1 - 3e-19 69.1 0.0 1e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Tower PF09121.10 OWF46973.1 - 3.2e-13 49.6 2.5 1.1e-12 47.9 2.5 2.1 1 0 0 1 1 1 1 Tower bZIP_1 PF00170.21 OWF46974.1 - 0.0002 21.4 11.9 0.0026 17.8 4.4 15.9 11 3 5 17 17 17 8 bZIP transcription factor Filament PF00038.21 OWF46974.1 - 0.00052 19.7 39.8 0.00052 19.7 39.8 7.3 2 1 4 6 6 6 2 Intermediate filament protein ERM PF00769.19 OWF46974.1 - 0.0056 16.5 36.2 0.0056 16.5 36.2 8.0 1 1 6 7 7 7 2 Ezrin/radixin/moesin family Fez1 PF06818.15 OWF46974.1 - 6.7 7.1 140.5 0.68 10.4 2.4 8.0 1 1 5 6 6 6 0 Fez1 C2 PF00168.30 OWF46975.1 - 5.7e-16 58.7 0.2 4.6e-10 39.7 0.1 2.5 2 0 0 2 2 2 2 C2 domain Polo_box_3 PF18544.1 OWF46975.1 - 0.066 13.9 0.1 0.66 10.6 0.0 2.4 2 0 0 2 2 2 0 Polo box domain CSTF1_dimer PF16699.5 OWF46975.1 - 0.13 12.1 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Cleavage stimulation factor subunit 1, dimerisation domain EphA2_TM PF14575.6 OWF46975.1 - 0.13 13.2 0.1 0.33 11.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Plasmid_stab_B PF10784.9 OWF46975.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Plasmid stability protein RRM_1 PF00076.22 OWF46976.1 - 3.2e-30 103.7 0.8 5.2e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF46976.1 - 1.2e-11 44.5 1.4 0.00015 21.8 0.3 2.6 2 1 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 OWF46976.1 - 0.13 12.0 0.8 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM PF05172.13 OWF46976.1 - 0.24 11.4 0.1 0.66 10.0 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PAP2 PF01569.21 OWF46977.1 - 5.4e-23 81.3 1.6 9.9e-23 80.4 1.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OWF46977.1 - 0.04 14.5 2.8 0.04 14.5 2.8 2.1 3 0 0 3 3 3 0 PAP2 superfamily C-terminal PAP2_3 PF14378.6 OWF46977.1 - 0.1 12.3 4.2 0.069 12.8 1.8 2.0 2 1 0 2 2 2 0 PAP2 superfamily zf-H2C2_5 PF13909.6 OWF46978.1 - 1.4e-06 27.9 9.3 2.6e-06 27.1 1.7 2.8 2 1 1 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF46978.1 - 0.00038 20.7 7.5 0.0027 18.1 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Osteoregulin PF07175.11 OWF46978.1 - 0.0011 19.2 0.5 0.0018 18.5 0.5 1.4 1 0 0 1 1 1 1 Osteoregulin Pes-10 PF07149.11 OWF46978.1 - 0.38 9.8 2.3 0.53 9.3 2.3 1.1 1 0 0 1 1 1 0 Pes-10 Pkinase PF00069.25 OWF46979.1 - 2.1e-76 256.8 0.0 2.8e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF46979.1 - 1.4e-45 155.7 0.0 1.8e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF46979.1 - 4.8e-07 29.4 0.0 1.8e-06 27.5 0.0 1.9 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OWF46979.1 - 0.00024 20.8 0.2 0.00047 19.8 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OWF46979.1 - 0.0021 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF46979.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain UBA_2 PF08587.11 OWF46979.1 - 0.02 15.0 0.5 0.061 13.4 0.5 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YrbL-PhoP_reg PF10707.9 OWF46979.1 - 0.063 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UBA PF00627.31 OWF46979.1 - 0.065 13.2 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 UBA/TS-N domain PPPI_inhib PF14895.6 OWF46980.1 - 6.6e-27 94.6 0.0 2.9e-24 85.9 0.3 2.3 1 1 1 2 2 2 2 Protein phosphatase 1 inhibitor tRNA-synt_1 PF00133.22 OWF46981.1 - 6.1e-156 520.2 1.3 8.3e-156 519.7 1.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OWF46981.1 - 2.2e-27 95.9 0.0 5.1e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OWF46981.1 - 1.2e-24 86.8 0.7 2e-16 59.8 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OWF46981.1 - 7.2e-08 32.2 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OWF46981.1 - 2.4e-05 23.8 0.0 0.081 12.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DUF1084 PF06454.11 OWF46982.1 - 5.3e-05 22.7 22.7 9e-05 22.0 22.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Trehalose_recp PF06151.13 OWF46983.1 - 1.1e-18 67.1 16.8 1.8e-17 63.0 16.8 2.1 1 1 0 1 1 1 1 Trehalose receptor 7tm_7 PF08395.12 OWF46983.1 - 7.4e-18 64.9 20.1 1.1e-17 64.3 20.1 1.3 1 0 0 1 1 1 1 7tm Chemosensory receptor Luteo_coat PF00894.18 OWF46983.1 - 0.078 12.9 1.7 6.7 6.6 0.2 2.5 1 1 1 2 2 2 0 Luteovirus coat protein FIT1_2 PF17357.2 OWF46983.1 - 0.16 12.0 2.0 10 6.3 0.1 3.0 2 1 1 3 3 3 0 Facilitor Of iron transport 1 and 2 Senescence PF06911.12 OWF46983.1 - 0.6 10.4 3.8 22 5.3 3.8 2.4 1 1 0 1 1 1 0 Senescence-associated protein LAGLIDADG_3 PF14528.6 OWF46983.1 - 5.8 7.3 5.7 31 5.0 0.7 2.7 1 1 1 2 2 2 0 LAGLIDADG-like domain 7tm_7 PF08395.12 OWF46984.1 - 7.5e-19 68.2 20.9 9.2e-19 67.9 20.9 1.0 1 0 0 1 1 1 1 7tm Chemosensory receptor Trehalose_recp PF06151.13 OWF46984.1 - 1.7e-14 53.3 12.1 1.7e-14 53.3 12.1 1.5 1 1 0 1 1 1 1 Trehalose receptor NTR PF01759.21 OWF46984.1 - 0.11 12.3 0.4 0.46 10.3 0.1 1.9 2 0 0 2 2 2 0 UNC-6/NTR/C345C module Trehalose_recp PF06151.13 OWF46985.1 - 0.013 14.1 18.0 0.32 9.6 18.0 2.2 1 1 0 1 1 1 0 Trehalose receptor Renin_r PF07850.14 OWF46985.1 - 0.06 14.0 1.3 0.16 12.6 0.2 2.2 2 0 0 2 2 2 0 Renin receptor-like protein HAP2-GCS1 PF10699.9 OWF46986.1 - 1.3e-14 53.9 0.1 4.9e-14 52.0 0.1 2.1 1 0 0 1 1 1 1 Male gamete fusion factor Cyt-b5 PF00173.28 OWF46987.1 - 1e-10 41.6 0.2 1.4e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Actin PF00022.19 OWF46988.1 - 1.2e-112 376.5 0.0 1e-111 373.5 0.0 1.9 1 1 0 1 1 1 1 Actin DUF1702 PF08012.11 OWF46988.1 - 0.045 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Metallothio_11 PF02066.15 OWF46989.1 - 0.066 13.4 10.8 13 6.1 0.0 4.0 2 1 2 4 4 4 0 Metallothionein family 11 eIF-5_eIF-2B PF01873.17 OWF46990.1 - 2.3e-41 140.3 0.4 6.1e-41 139.0 0.1 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 OWF46990.1 - 4.3e-11 42.8 0.2 1.2e-10 41.3 0.2 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF2387 PF09526.10 OWF46990.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Ribosomal_S27e PF01667.17 OWF46990.1 - 0.28 10.9 1.8 0.83 9.4 1.8 1.7 1 0 0 1 1 1 0 Ribosomal protein S27 TPR_12 PF13424.6 OWF46991.1 - 9.5e-76 250.1 26.6 7.4e-21 74.2 1.7 4.9 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OWF46991.1 - 4.6e-63 207.5 13.6 1.5e-15 56.5 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 OWF46991.1 - 4e-33 111.0 15.3 5.3e-06 26.1 0.0 6.8 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF46991.1 - 7.7e-30 101.5 31.6 1.7e-07 30.7 0.5 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OWF46991.1 - 2.6e-21 74.0 28.5 0.00033 20.6 2.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OWF46991.1 - 8.1e-19 66.2 23.8 0.0018 18.3 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF46991.1 - 2.2e-14 53.8 12.8 0.00079 20.0 1.5 5.7 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF46991.1 - 1.2e-12 47.4 9.1 0.54 11.2 0.2 6.7 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF46991.1 - 1.6e-11 44.5 11.7 7.8e-05 23.1 1.2 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF46991.1 - 3.4e-11 43.1 1.7 3.4e-11 43.1 1.7 3.3 3 1 0 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 OWF46991.1 - 5.4e-11 42.1 11.2 0.027 14.8 0.4 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 OWF46991.1 - 1.6e-09 37.4 0.0 7.4 7.5 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF46991.1 - 6.6e-08 32.7 11.0 0.00069 19.8 0.1 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 OWF46991.1 - 0.0012 18.9 7.4 0.22 11.9 0.0 5.6 7 0 0 7 7 5 1 PPR repeat NUDE_C PF04880.13 OWF46991.1 - 0.0017 18.8 2.3 0.0034 17.9 2.3 1.6 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region TPR_3 PF07720.12 OWF46991.1 - 0.0032 17.4 14.3 0.36 10.9 0.4 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat GHL5 PF14872.6 OWF46991.1 - 0.015 13.4 3.0 0.028 12.5 3.0 1.4 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Wzy_C_2 PF11846.8 OWF46991.1 - 0.018 15.0 2.9 3.4 7.6 0.1 4.4 3 1 1 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal PPR_2 PF13041.6 OWF46991.1 - 0.025 14.8 4.0 2.6 8.3 0.0 4.1 4 0 0 4 4 3 0 PPR repeat family DUF4919 PF16266.5 OWF46991.1 - 0.089 12.7 2.3 0.33 10.9 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4919) JIP_LZII PF16471.5 OWF46991.1 - 0.11 12.7 14.8 0.12 12.5 4.9 3.6 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II TPR_11 PF13414.6 OWF46991.1 - 0.12 12.1 26.0 0.17 11.6 0.3 6.7 7 0 0 7 7 7 0 TPR repeat TPR_6 PF13174.6 OWF46991.1 - 0.42 11.4 20.4 1.3 9.8 0.8 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 OWF46991.1 - 0.46 10.2 8.5 1.4 8.6 0.6 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 OWF46991.1 - 0.48 10.1 9.3 4.2 7.0 0.2 3.9 3 1 0 4 4 3 0 26S proteasome subunit RPN7 Csm1_N PF18504.1 OWF46991.1 - 0.7 10.3 6.9 0.98 9.8 4.6 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain ATG16 PF08614.11 OWF46991.1 - 0.86 9.8 20.2 1.1 9.4 13.3 3.6 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 OWF46991.1 - 1.3 9.7 13.2 1.5 9.4 10.5 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FapA PF03961.13 OWF46991.1 - 1.5 7.4 7.8 2.9 6.4 7.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A COG2 PF06148.11 OWF46991.1 - 1.5 8.9 7.5 1.7 8.7 5.5 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1897 PF09005.10 OWF46991.1 - 1.7 8.2 5.4 10 5.7 0.2 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF1897) DUF627 PF04781.12 OWF46991.1 - 1.9 8.5 9.1 4.8 7.2 0.0 4.3 6 0 0 6 6 3 0 Protein of unknown function (DUF627) TPR_20 PF14561.6 OWF46991.1 - 2.4 8.6 11.4 9.7 6.6 0.4 4.9 3 1 3 6 6 5 0 Tetratricopeptide repeat Laminin_II PF06009.12 OWF46991.1 - 3.1 7.8 11.4 3.4 7.7 3.6 2.5 1 1 1 2 2 2 0 Laminin Domain II TMF_TATA_bd PF12325.8 OWF46991.1 - 3.2 8.0 21.0 0.058 13.6 9.7 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SOGA PF11365.8 OWF46991.1 - 6.5 8.0 16.4 1.1 10.5 2.2 3.6 2 1 2 4 4 3 0 Protein SOGA YabA PF06156.13 OWF46991.1 - 8.2 7.1 14.4 1.3 9.7 7.3 3.1 1 1 0 2 2 2 0 Initiation control protein YabA CBFD_NFYB_HMF PF00808.23 OWF46992.1 - 7.7e-17 61.3 1.7 9.9e-17 61.0 1.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OWF46992.1 - 4.9e-13 49.6 1.6 5.9e-13 49.3 1.6 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OWF46992.1 - 0.02 15.0 0.2 0.027 14.6 0.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OWF46992.1 - 0.071 13.3 1.6 0.11 12.7 1.6 1.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Cpn60_TCP1 PF00118.24 OWF46993.1 - 3.8e-49 167.6 0.6 5.7e-49 167.1 0.6 1.2 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RTC4 PF14474.6 OWF46994.1 - 0.011 15.9 0.0 0.041 14.0 0.0 2.0 1 0 0 1 1 1 0 RTC4-like domain EF-hand_1 PF00036.32 OWF46995.1 - 2.4e-30 101.8 0.9 4.1e-07 29.1 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF46995.1 - 3.6e-27 94.6 0.1 2.5e-13 50.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF46995.1 - 1.4e-25 88.8 2.6 2e-10 40.4 0.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF46995.1 - 2.5e-22 76.8 0.5 5.3e-07 29.1 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OWF46995.1 - 1.9e-16 58.7 0.5 8e-05 22.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OWF46995.1 - 2.6e-10 40.4 0.0 2.1e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF46995.1 - 6.4e-06 26.5 0.0 0.003 17.9 0.0 2.0 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF46995.1 - 7e-06 26.0 0.0 0.45 10.6 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF46995.1 - 6.6e-05 23.0 0.4 0.25 11.6 0.0 2.8 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_4 PF12763.7 OWF46995.1 - 0.00037 20.4 0.0 0.063 13.2 0.0 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 OWF46995.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.8 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 OWF46995.1 - 0.041 14.8 0.0 0.29 12.0 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain CCD48 PF15799.5 OWF46995.1 - 0.1 10.9 0.0 0.15 10.3 0.0 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 LXG PF04740.12 OWF46996.1 - 0.0011 18.7 1.0 0.0011 18.7 1.0 8.0 2 1 5 8 8 8 2 LXG domain of WXG superfamily CENP-F_leu_zip PF10473.9 OWF46996.1 - 0.0017 18.4 12.6 0.0017 18.4 12.6 10.0 4 4 3 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 OWF46996.1 - 0.0077 16.0 11.5 0.0077 16.0 11.5 6.5 2 1 6 8 8 8 1 Protein of unknown function (DUF745) Occludin_ELL PF07303.13 OWF46996.1 - 0.049 14.4 0.7 0.049 14.4 0.7 11.6 4 2 7 13 13 13 0 Occludin homology domain Fe-S_biosyn PF01521.20 OWF46997.1 - 1.5e-14 54.1 0.1 2e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hfx_Cass5 PF18287.1 OWF46997.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 Pkinase PF00069.25 OWF46999.1 - 1.8e-65 221.0 0.0 2.6e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF46999.1 - 4.5e-37 127.7 0.0 6.3e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 OWF46999.1 - 3e-33 113.5 27.4 2.2e-17 62.7 6.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 OWF46999.1 - 9.9e-16 57.9 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 OWF46999.1 - 1.1e-11 45.3 1.5 2.1e-11 44.3 1.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 OWF46999.1 - 0.0013 18.7 0.2 0.0044 17.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family C1_2 PF03107.16 OWF46999.1 - 0.0016 18.7 18.7 0.046 14.0 4.4 2.7 2 0 0 2 2 2 2 C1 domain Kinase-like PF14531.6 OWF46999.1 - 0.0032 16.8 0.0 0.0075 15.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF46999.1 - 0.0063 15.5 0.1 0.0093 14.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF46999.1 - 0.0083 15.5 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OWF46999.1 - 0.03 13.9 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Zf_RING PF16744.5 OWF46999.1 - 0.11 12.7 13.8 0.09 12.9 3.6 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_9 PF13901.6 OWF46999.1 - 0.11 12.5 18.8 0.79 9.7 3.8 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon RIO1 PF01163.22 OWF46999.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PHD PF00628.29 OWF46999.1 - 3 7.8 22.0 0.88 9.5 4.9 2.6 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 OWF46999.1 - 9.2 6.7 25.8 6.1 7.2 5.8 2.7 2 0 0 2 2 2 0 RING-like domain ATG16 PF08614.11 OWF47000.1 - 0.00038 20.7 0.7 0.00038 20.7 0.7 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) F-box PF00646.33 OWF47000.1 - 0.0028 17.5 0.1 0.0092 15.8 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OWF47000.1 - 0.0071 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OWF47000.1 - 0.027 14.4 0.1 0.079 12.9 0.1 1.8 1 0 0 1 1 1 0 F-box DUF16 PF01519.16 OWF47000.1 - 0.16 12.5 11.9 1.3 9.5 6.6 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Sec34 PF04136.15 OWF47000.1 - 0.57 10.0 10.7 0.33 10.8 5.5 2.3 2 0 0 2 2 2 0 Sec34-like family DUF2935 PF11155.8 OWF47000.1 - 0.86 9.9 4.7 1.1 9.6 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF2408 PF10303.9 OWF47000.1 - 2.1 8.9 13.7 1 9.9 10.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) HemX PF04375.14 OWF47000.1 - 4.7 6.4 11.2 0.94 8.7 6.6 1.9 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase PRANC PF09372.10 OWF47000.1 - 5.7 7.3 7.9 0.78 10.1 0.7 2.5 2 1 0 2 2 2 0 PRANC domain MPS2 PF17060.5 OWF47000.1 - 7.4 5.7 13.1 1.7 7.8 9.7 1.7 2 1 0 2 2 2 0 Monopolar spindle protein 2 SYCE1 PF15233.6 OWF47000.1 - 8.3 6.5 18.1 0.8 9.8 11.7 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 SlyX PF04102.12 OWF47000.1 - 9 7.0 11.3 2.6 8.7 2.7 3.5 2 1 1 3 3 3 0 SlyX PHR PF08005.12 OWF47001.1 - 1.4e-27 97.3 1.1 2.8e-27 96.2 1.1 1.5 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 OWF47001.1 - 4.7e-21 75.1 0.9 1.3e-19 70.4 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF47001.1 - 1.9e-13 50.4 2.2 5.6e-12 45.7 0.6 2.8 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 OWF47001.1 - 0.024 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) BTB PF00651.31 OWF47002.1 - 8.4e-34 116.1 0.3 2.2e-23 82.6 0.0 3.4 2 1 1 3 3 3 3 BTB/POZ domain PHR PF08005.12 OWF47002.1 - 4.1e-28 98.9 1.3 4.1e-28 98.9 1.3 2.0 2 0 0 2 2 2 1 PHR domain BACK PF07707.15 OWF47002.1 - 4e-13 49.3 1.2 6.8e-12 45.4 0.5 2.7 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 OWF47002.1 - 0.0016 18.5 0.1 0.0034 17.4 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4082) PHR PF08005.12 OWF47003.1 - 3.1e-24 86.4 0.9 5.7e-24 85.5 0.9 1.5 1 0 0 1 1 1 1 PHR domain BACK PF07707.15 OWF47003.1 - 1.8e-13 50.5 1.1 2.3e-12 46.9 0.3 2.7 2 1 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF47003.1 - 3.8e-07 30.3 0.8 5.3e-05 23.4 0.2 2.6 1 1 1 2 2 2 2 BTB/POZ domain HIPIP PF01355.17 OWF47003.1 - 1.3 9.5 3.5 38 4.7 0.1 3.0 3 0 0 3 3 3 0 High potential iron-sulfur protein Globin PF00042.22 OWF47004.1 - 1.8e-16 60.7 0.0 2.3e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Globin MFS_1 PF07690.16 OWF47005.1 - 2.1e-24 86.1 40.3 1.3e-17 63.8 19.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF47005.1 - 4.6e-07 29.1 13.6 4.6e-07 29.1 13.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5115 PF17142.4 OWF47005.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5115) MFS_1 PF07690.16 OWF47006.1 - 2e-17 63.1 32.3 2e-17 63.1 32.3 2.6 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF47007.1 - 4.1e-23 81.9 44.0 6.3e-16 58.2 19.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 OWF47007.1 - 0.0016 16.7 5.7 0.0016 16.7 5.7 2.1 2 0 0 2 2 2 2 BT1 family MFS_1 PF07690.16 OWF47008.1 - 2.2e-14 53.1 3.1 2.3e-14 53.1 3.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 OWF47008.1 - 0.0053 15.2 0.4 0.0077 14.7 0.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector ER PF01133.17 OWF47009.1 - 2.5e-74 245.5 1.1 9.4e-41 137.8 0.1 2.1 2 0 0 2 2 2 2 Enhancer of rudimentary Pex19 PF04614.12 OWF47009.1 - 0.004 17.0 0.1 2.2 8.0 0.0 2.1 2 0 0 2 2 2 2 Pex19 protein family HSR PF03172.13 OWF47009.1 - 0.005 17.0 0.4 0.57 10.4 0.0 2.5 2 0 0 2 2 2 1 HSR domain SGIII PF15467.6 OWF47009.1 - 0.0067 15.7 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 1 Secretogranin-3 Pro_sub2 PF18513.1 OWF47009.1 - 0.023 14.9 1.5 5.1 7.3 0.0 2.7 2 1 0 2 2 2 0 Prodomain subtilisin 2 Pox_polyA_pol PF03296.13 OWF47009.1 - 0.041 13.8 0.0 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Mce4_CUP1 PF11887.8 OWF47009.1 - 0.044 13.2 0.0 0.95 8.9 0.0 2.1 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DNA_ligase_A_N PF04675.14 OWF47009.1 - 0.052 13.9 0.0 5.3 7.3 0.0 2.1 2 0 0 2 2 2 0 DNA ligase N terminus Dsl1_C PF11989.8 OWF47009.1 - 0.057 13.1 0.0 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 C terminal DUF2816 PF10992.8 OWF47009.1 - 0.078 12.9 0.1 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) Antimicrobial25 PF16839.5 OWF47009.1 - 0.47 10.6 2.7 27 4.9 0.3 2.8 3 0 0 3 3 3 0 Nematode antimicrobial peptide Zip PF02535.22 OWF47010.1 - 1.2e-38 133.2 23.8 3.8e-27 95.4 10.1 2.4 1 1 1 2 2 2 2 ZIP Zinc transporter MTS PF05175.14 OWF47012.1 - 8.9e-19 67.7 0.1 1.2e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OWF47012.1 - 5.3e-13 49.0 0.2 8.3e-13 48.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OWF47012.1 - 4.3e-12 46.6 0.2 9.3e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF47012.1 - 9.9e-12 44.9 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 OWF47012.1 - 3.5e-11 43.1 0.4 4.9e-11 42.6 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF47012.1 - 2.1e-08 34.7 0.1 4.5e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OWF47012.1 - 8.4e-07 28.7 0.2 1.6e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 OWF47012.1 - 1.4e-06 28.1 0.2 2.5e-06 27.3 0.1 1.6 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 OWF47012.1 - 4.4e-06 26.8 0.1 6.5e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF47012.1 - 1.1e-05 26.1 0.2 3e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 OWF47012.1 - 1.8e-05 24.1 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_16 PF10294.9 OWF47012.1 - 0.00016 21.5 0.1 0.00027 20.7 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase DUF43 PF01861.16 OWF47012.1 - 0.003 16.8 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MetW PF07021.12 OWF47012.1 - 0.0047 16.6 0.2 0.0078 15.8 0.2 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DNA_methylase PF00145.17 OWF47012.1 - 0.0074 15.7 0.1 0.013 14.8 0.0 1.4 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase GcpE PF04551.14 OWF47012.1 - 0.023 13.8 0.2 0.044 12.9 0.2 1.4 1 0 0 1 1 1 0 GcpE protein Methyltransf_5 PF01795.19 OWF47012.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family CheR PF01739.18 OWF47012.1 - 0.078 12.4 0.7 1.3 8.5 0.2 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 OWF47012.1 - 0.13 11.2 1.3 0.12 11.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 OWF47013.1 - 8.9e-85 284.0 0.2 1.4e-84 283.4 0.2 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OWF47013.1 - 8.6e-07 29.5 0.0 5.7e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF47013.1 - 1.4e-05 25.7 0.0 0.001 19.7 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 OWF47013.1 - 0.00045 19.8 0.1 0.002 17.7 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OWF47013.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OWF47013.1 - 0.004 16.9 0.1 0.099 12.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OWF47013.1 - 0.023 13.9 0.6 0.055 12.7 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 OWF47013.1 - 0.073 13.8 0.4 11 6.9 0.0 3.2 2 1 1 3 3 3 0 Methyltransferase domain Protamine_P2 PF00841.19 OWF47013.1 - 0.99 9.9 8.2 0.096 13.2 2.6 2.2 2 0 0 2 2 2 0 Sperm histone P2 Trypsin_2 PF13365.6 OWF47015.1 - 0.037 14.9 0.0 0.068 14.1 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain DED PF01335.21 OWF47015.1 - 0.086 13.2 0.2 2.6 8.4 0.1 2.8 3 0 0 3 3 3 0 Death effector domain DUF3242 PF11586.8 OWF47015.1 - 0.1 12.3 0.3 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) ERM PF00769.19 OWF47016.1 - 3.2e-34 118.8 60.9 3.2e-34 118.8 60.9 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 OWF47016.1 - 4.3e-26 91.1 0.0 2.2e-25 88.9 0.0 2.3 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 OWF47016.1 - 4.3e-20 72.3 0.2 4.3e-20 72.3 0.2 2.8 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 OWF47016.1 - 6.7e-14 51.6 1.9 8.7e-14 51.2 0.3 2.1 2 0 0 2 2 2 1 FERM N-terminal domain Wtap PF17098.5 OWF47017.1 - 1.8e-60 203.4 14.5 1.8e-60 203.4 14.5 2.7 2 1 1 3 3 3 1 WTAP/Mum2p family RBD-FIP PF09457.10 OWF47017.1 - 0.051 13.5 5.8 0.78 9.7 0.8 2.9 2 0 0 2 2 2 0 FIP domain ANTH PF07651.16 OWF47017.1 - 0.19 10.7 7.2 0.063 12.3 3.4 2.1 1 1 0 1 1 1 0 ANTH domain T2SSF PF00482.23 OWF47017.1 - 0.19 11.7 3.4 0.21 11.5 1.4 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Sugar_tr PF00083.24 OWF47018.1 - 3.2e-30 105.4 12.8 5.4e-30 104.6 12.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF47018.1 - 1.5e-16 60.3 15.0 1.5e-16 60.3 15.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF47019.1 - 4.4e-34 118.1 11.1 5.8e-34 117.7 11.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF47019.1 - 5.9e-22 78.1 49.8 4e-17 62.2 29.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 OWF47019.1 - 0.029 14.9 0.0 0.054 14.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 OWF47020.1 - 3.8e-34 118.3 11.1 4.8e-34 118.0 11.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF47020.1 - 2.7e-22 79.2 49.3 3.8e-17 62.2 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 OWF47020.1 - 0.028 14.9 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Glycos_transf_3 PF00591.21 OWF47021.1 - 1e-32 113.8 0.1 1.4e-32 113.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OWF47021.1 - 7.7e-20 70.5 0.1 1.5e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 OWF47021.1 - 4.6e-13 48.6 0.0 9.7e-13 47.6 0.0 1.6 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain DUF3422 PF11902.8 OWF47021.1 - 0.058 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF3187 PF11383.8 OWF47022.1 - 0.53 9.4 8.5 7 5.7 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3187) F-box_4 PF15966.5 OWF47022.1 - 1.4 8.8 10.3 2.2 8.2 4.5 2.1 1 1 1 2 2 2 0 F-box IclR PF01614.18 OWF47022.1 - 4.8 7.0 10.2 24 4.8 0.5 3.4 1 1 4 5 5 5 0 Bacterial transcriptional regulator DUF4279 PF14106.6 OWF47022.1 - 4.8 7.4 13.9 19 5.5 3.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) C1_4 PF07975.12 OWF47022.1 - 7.4 6.9 13.3 16 5.9 1.5 3.7 1 1 2 3 3 3 0 TFIIH C1-like domain Ank_2 PF12796.7 OWF47023.1 - 2.1e-56 188.5 8.5 3.3e-15 56.4 0.3 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF47023.1 - 1.2e-47 159.7 12.7 3.6e-10 40.2 0.1 10.1 3 1 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF47023.1 - 3.8e-45 151.4 19.1 2.4e-07 30.9 0.1 9.2 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 OWF47023.1 - 1.8e-40 135.6 20.0 0.0001 22.6 0.1 11.4 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 OWF47023.1 - 2.6e-40 131.8 12.9 0.00032 20.9 0.0 11.3 11 0 0 11 11 11 8 Ankyrin repeat DUF1296 PF06972.11 OWF47023.1 - 0.079 13.1 0.1 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF5631 PF18645.1 OWF47024.1 - 0.035 14.5 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5631) CelTOS PF18659.1 OWF47025.1 - 3.8e-07 30.6 11.3 7.6 7.0 0.0 7.3 1 1 6 7 7 7 3 Cell-traversal protein for ookinetes and sporozoites DUF1580 PF07618.11 OWF47025.1 - 0.00013 21.5 3.0 22 4.8 0.0 6.2 6 2 2 8 8 8 1 Protein of unknown function (DUF1580) BssC_TutF PF08201.11 OWF47025.1 - 0.06 13.4 1.6 7.1 6.7 0.0 4.6 4 2 2 6 6 6 0 BssC/TutF protein MCM_OB PF17207.3 OWF47025.1 - 0.15 11.9 0.2 1.2e+02 2.5 0.0 4.2 2 1 3 5 5 5 0 MCM OB domain DNA_pol3_theta PF06440.11 OWF47025.1 - 0.38 10.5 1.8 61 3.4 0.0 4.5 3 3 5 8 8 8 0 DNA polymerase III, theta subunit F-box PF00646.33 OWF47025.1 - 1.6 8.7 9.9 3.7 7.5 0.2 5.3 4 2 2 7 7 7 0 F-box domain TERF2_RBM PF16772.5 OWF47026.1 - 0.00097 18.5 15.7 1.2 8.7 0.6 7.1 2 2 8 10 10 10 3 Telomeric repeat-binding factor 2 Rap1-binding motif Cys_Knot_tox PF17486.2 OWF47026.1 - 2.1 8.6 37.8 1.7 8.9 3.6 4.2 1 1 3 4 4 4 0 Cystine knot toxins Amidinotransf PF02274.17 OWF47027.1 - 3.6e-09 36.2 0.1 3.7e-07 29.6 0.1 2.2 1 1 0 1 1 1 1 Amidinotransferase MAM PF00629.23 OWF47028.1 - 4.4e-33 114.5 0.1 3.4e-22 79.1 0.0 2.1 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu EGF PF00008.27 OWF47028.1 - 4.3e-14 52.5 26.0 6.9e-08 32.6 6.6 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 OWF47028.1 - 3.1e-09 37.1 21.7 4.4e-05 24.0 6.2 3.6 3 0 0 3 3 3 2 Human growth factor-like EGF cEGF PF12662.7 OWF47028.1 - 1e-05 25.3 3.3 1e-05 25.3 3.3 3.3 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF_2 PF07974.13 OWF47028.1 - 0.001 19.4 31.6 0.15 12.4 9.1 2.8 2 1 0 2 2 2 2 EGF-like domain EGF_CA PF07645.15 OWF47028.1 - 0.076 13.2 29.8 1.2 9.4 7.8 2.8 2 1 0 2 2 2 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF47028.1 - 9.8 6.6 25.2 1.7 9.0 8.8 2.9 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site ECH_1 PF00378.20 OWF47029.1 - 1.7e-34 119.3 0.0 2.1e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF47029.1 - 2e-13 50.6 0.1 7.6e-11 42.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PspB PF06667.12 OWF47030.1 - 0.0003 20.8 0.3 0.00064 19.7 0.3 1.5 1 0 0 1 1 1 1 Phage shock protein B DUF3139 PF11337.8 OWF47030.1 - 0.0012 19.5 0.7 0.0033 18.1 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) TssO PF17561.2 OWF47030.1 - 0.0016 18.6 1.1 0.0065 16.6 0.3 2.1 2 0 0 2 2 2 1 Type VI secretion system, TssO DUF3021 PF11457.8 OWF47030.1 - 0.0032 17.8 3.0 0.0054 17.1 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3021) MAP17 PF15807.5 OWF47030.1 - 0.0037 17.5 8.4 0.0081 16.4 0.1 2.3 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF1282 PF06930.12 OWF47030.1 - 0.0062 16.3 2.0 0.011 15.5 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) EphA2_TM PF14575.6 OWF47030.1 - 0.0076 17.1 2.1 0.016 16.1 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Sm_multidrug_ex PF06695.11 OWF47030.1 - 0.014 16.0 0.0 0.037 14.7 0.0 1.7 1 0 0 1 1 1 0 Putative small multi-drug export protein ETRAMP PF09716.10 OWF47030.1 - 0.039 14.0 2.4 0.039 14.0 2.4 2.8 3 0 0 3 3 2 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 OWF47030.1 - 0.049 13.9 0.8 0.18 12.1 0.8 1.9 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Vpu PF00558.19 OWF47030.1 - 0.055 13.2 0.7 0.055 13.2 0.7 1.9 2 0 0 2 2 1 0 Vpu protein Phage_Gp23 PF10669.9 OWF47030.1 - 0.059 13.7 0.1 0.059 13.7 0.1 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) MAS20 PF02064.15 OWF47030.1 - 0.072 13.2 0.1 0.072 13.2 0.1 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor Insulin_TMD PF17870.1 OWF47030.1 - 0.1 12.7 2.2 0.22 11.6 2.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Stevor PF17410.2 OWF47030.1 - 0.11 12.0 5.0 0.22 11.0 5.0 1.6 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame EVC2_like PF12297.8 OWF47030.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein SHR3_chaperone PF08229.11 OWF47030.1 - 0.17 10.8 0.0 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 ER membrane protein SH3 DUF4381 PF14316.6 OWF47030.1 - 0.18 12.1 0.3 0.4 10.9 0.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) DUF2681 PF10883.8 OWF47030.1 - 0.22 12.0 0.3 0.22 12.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2371 PF10177.9 OWF47030.1 - 0.31 11.2 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Conotoxin PF02950.17 OWF47030.1 - 0.34 12.0 5.6 6.7 7.8 0.0 3.4 3 0 0 3 3 3 0 Conotoxin SpoIIIAH PF12685.7 OWF47030.1 - 1.1 9.0 9.7 6.9 6.4 9.7 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4834 PF16118.5 OWF47030.1 - 5 8.1 12.8 6.2e+02 1.4 12.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 OWF47030.1 - 7.6 6.2 6.7 4.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Connexin SAM_1 PF00536.30 OWF47031.1 - 7e-07 29.6 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF47031.1 - 6.1e-06 26.3 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CABIT PF12736.7 OWF47031.1 - 2.4e-05 23.8 0.1 0.0031 16.9 0.0 2.3 1 1 1 2 2 2 2 Cell-cycle sustaining, positive selection, DUF4169 PF13770.6 OWF47031.1 - 0.15 12.4 0.7 0.44 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) SAM_1 PF00536.30 OWF47032.1 - 4.5e-06 27.0 0.8 2e-05 24.9 0.2 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF47032.1 - 0.012 15.7 0.1 0.035 14.2 0.1 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Poxvirus_B22R PF04395.12 OWF47032.1 - 0.23 11.0 2.3 0.15 11.6 0.2 1.7 2 0 0 2 2 2 0 Poxvirus B22R protein SAM_1 PF00536.30 OWF47033.1 - 4.2e-06 27.1 0.1 1e-05 25.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF47033.1 - 1.5e-05 25.0 0.1 6.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) CABIT PF12736.7 OWF47033.1 - 0.0015 17.9 0.0 0.0077 15.6 0.0 1.8 1 1 1 2 2 2 2 Cell-cycle sustaining, positive selection, SSF PF00474.17 OWF47034.1 - 1.3e-136 455.7 22.6 2.5e-136 454.8 22.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5480 PF17576.2 OWF47034.1 - 0.022 14.7 1.8 0.35 10.9 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5480) Orf78 PF06024.12 OWF47034.1 - 0.18 12.1 1.5 0.64 10.3 0.1 2.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF4600 PF15372.6 OWF47035.1 - 4.3e-31 108.0 9.6 4.3e-31 108.0 9.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4600) Uso1_p115_C PF04871.13 OWF47035.1 - 0.0021 18.4 15.1 0.071 13.5 0.3 2.3 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_I PF06008.14 OWF47035.1 - 0.013 15.3 12.0 0.016 14.9 12.0 1.2 1 0 0 1 1 1 0 Laminin Domain I ZapB PF06005.12 OWF47035.1 - 0.015 15.7 1.4 0.015 15.7 1.4 3.1 2 1 1 3 3 3 0 Cell division protein ZapB GAS PF13851.6 OWF47035.1 - 0.034 13.5 20.6 0.024 14.0 10.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KELK PF15796.5 OWF47035.1 - 0.039 14.4 2.9 0.039 14.4 2.9 3.2 1 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PI3K_P85_iSH2 PF16454.5 OWF47035.1 - 0.056 13.0 14.5 0.96 9.0 9.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 OWF47035.1 - 0.11 12.5 9.4 0.41 10.7 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HisKA_3 PF07730.13 OWF47035.1 - 0.13 12.8 1.3 12 6.5 0.1 2.8 2 1 0 2 2 2 0 Histidine kinase EzrA PF06160.12 OWF47035.1 - 0.17 10.0 16.7 1.2 7.2 16.7 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 OWF47035.1 - 0.22 11.7 14.5 0.31 11.2 0.8 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 OWF47035.1 - 0.29 10.6 7.2 0.42 10.1 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 OWF47035.1 - 0.3 11.6 3.8 1.2 9.7 1.1 2.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 OWF47035.1 - 0.35 11.0 19.5 0.21 11.7 12.0 2.1 1 1 0 1 1 1 0 Tropomyosin like DUF948 PF06103.11 OWF47035.1 - 0.35 11.1 0.9 1.3 9.3 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 OWF47035.1 - 0.43 10.6 15.2 0.044 13.9 6.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.13 OWF47035.1 - 0.47 10.1 8.0 0.77 9.5 7.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TMPIT PF07851.13 OWF47035.1 - 0.51 9.5 8.9 0.12 11.6 5.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein OTU PF02338.19 OWF47035.1 - 0.68 10.4 7.1 6.1 7.3 1.1 2.1 1 1 1 2 2 2 0 OTU-like cysteine protease Laminin_II PF06009.12 OWF47035.1 - 0.87 9.6 8.5 0.43 10.6 3.5 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4686 PF15742.5 OWF47035.1 - 0.88 8.6 20.1 3.4 6.7 20.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) DUF2951 PF11166.8 OWF47035.1 - 2.1 8.6 15.2 0.046 13.9 4.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) PspA_IM30 PF04012.12 OWF47035.1 - 2.3 7.8 14.8 1.3 8.5 8.3 2.6 1 1 1 2 2 2 0 PspA/IM30 family Ax_dynein_light PF10211.9 OWF47035.1 - 2.5 8.0 19.7 2.8 7.8 3.2 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain T3SSipB PF16535.5 OWF47035.1 - 2.8 8.4 10.0 2.3 8.7 6.2 2.2 1 1 0 1 1 1 0 Type III cell invasion protein SipB T3SS_needle_F PF09392.10 OWF47035.1 - 3.8 7.8 7.7 2.9 8.1 1.6 2.9 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF FlxA PF14282.6 OWF47035.1 - 3.9 7.5 15.0 1.4 8.9 8.4 2.4 1 1 1 2 2 2 0 FlxA-like protein FapA PF03961.13 OWF47035.1 - 5.1 5.6 13.1 0.41 9.2 6.0 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A ALMT PF11744.8 OWF47035.1 - 5.3 5.8 7.7 6.9 5.4 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4200 PF13863.6 OWF47035.1 - 5.6 7.4 21.5 1.5 9.3 12.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 OWF47035.1 - 5.8 5.9 11.0 8.4 5.4 11.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec20 PF03908.13 OWF47035.1 - 8.3 6.4 7.4 3.1 7.8 1.6 2.4 1 1 2 3 3 3 0 Sec20 7tm_1 PF00001.21 OWF47036.1 - 2.5e-25 89.3 8.3 3.1e-25 89.0 8.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF47036.1 - 0.00046 19.6 6.6 0.095 12.0 1.5 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Git3 PF11710.8 OWF47036.1 - 0.36 10.6 7.9 0.55 10.0 5.9 2.5 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srz PF10325.9 OWF47036.1 - 0.37 10.1 9.8 0.055 12.8 3.6 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz DUF5345 PF17280.2 OWF47036.1 - 0.42 10.6 4.3 0.46 10.5 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5345) DUF2207 PF09972.9 OWF47036.1 - 9.8 4.8 7.3 7.5 5.2 0.0 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) 7tm_1 PF00001.21 OWF47037.1 - 1.4e-17 63.9 9.0 1.4e-17 63.9 9.0 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) SHP PF03579.13 OWF47037.1 - 4 7.5 7.2 1.4 9.0 0.1 3.1 3 0 0 3 3 3 0 Small hydrophobic protein PDZ PF00595.24 OWF47038.1 - 4.5e-14 52.6 1.4 9.5e-14 51.5 1.4 1.5 1 0 0 1 1 1 1 PDZ domain CH PF00307.31 OWF47038.1 - 2e-11 44.0 0.0 5.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.22 OWF47038.1 - 8.9e-08 32.3 7.5 1.7e-07 31.3 7.5 1.5 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 OWF47038.1 - 1.7e-05 24.6 1.6 3.4e-05 23.6 1.6 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF47038.1 - 0.001 19.3 2.3 0.0021 18.3 0.6 2.5 2 0 0 2 2 2 1 PDZ domain CAMSAP_CH PF11971.8 OWF47038.1 - 0.0043 16.9 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain TAFII55_N PF04658.13 OWF47039.1 - 9.1e-60 201.0 0.9 9.1e-60 201.0 0.9 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region Smac_DIABLO PF09057.10 OWF47039.1 - 0.0028 17.0 1.4 0.0059 16.0 1.4 1.5 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases CENP-B_dimeris PF09026.10 OWF47039.1 - 9.5 6.7 14.0 11 6.5 10.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2345 PF10106.9 OWF47040.1 - 0.00019 21.3 6.9 7 6.5 0.0 5.8 4 2 2 6 6 6 4 Uncharacterized protein conserved in bacteria (DUF2345) LSDAT_euk PF18139.1 OWF47041.1 - 1.8e-34 119.4 0.0 6.9e-34 117.4 0.0 1.9 1 1 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF47041.1 - 1.4e-11 44.1 0.0 0.0018 17.5 0.0 3.3 3 0 0 3 3 3 3 SLOG in TRPM, prokaryote HLH PF00010.26 OWF47042.1 - 1.2e-17 63.6 2.4 1.6e-17 63.2 0.3 2.4 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 OWF47042.1 - 0.00021 20.9 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain MRP-S22 PF10245.9 OWF47042.1 - 0.023 14.4 1.8 1.2 8.9 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S22 FlaC_arch PF05377.11 OWF47044.1 - 7.4e-06 26.3 1.0 0.75 10.2 0.0 3.4 2 1 1 3 3 3 3 Flagella accessory protein C (FlaC) QIL1 PF15884.5 OWF47044.1 - 0.00038 21.0 4.3 1.7 9.3 0.1 3.3 1 1 2 3 3 3 2 MICOS complex subunit MIC13, QIL1 DUF630 PF04783.12 OWF47044.1 - 0.009 16.2 2.3 34 4.7 0.1 4.3 2 1 1 3 3 3 0 Protein of unknown function (DUF630) DUF1048 PF06304.11 OWF47044.1 - 0.015 15.7 4.8 11 6.6 0.4 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1048) BAR_3_WASP_bdg PF10456.9 OWF47044.1 - 0.029 13.8 8.2 2.9 7.3 3.9 2.9 1 1 2 3 3 3 0 WASP-binding domain of Sorting nexin protein WASH_WAHD PF11945.8 OWF47044.1 - 0.11 12.0 0.4 1.8 8.1 0.1 2.3 1 1 1 2 2 2 0 WAHD domain of WASH complex NOC3p PF07540.11 OWF47044.1 - 0.42 11.1 1.5 2.5 8.6 0.1 2.5 1 1 1 2 2 2 0 Nucleolar complex-associated protein FAT PF02259.23 OWF47044.1 - 1.1 8.4 11.3 2.5 7.2 2.1 2.9 1 1 2 3 3 3 0 FAT domain DUF4509 PF14970.6 OWF47044.1 - 1.4 8.8 8.5 1.8 8.4 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) MKT1_C PF12246.8 OWF47044.1 - 1.6 7.9 3.7 18 4.5 0.1 2.6 1 1 2 3 3 3 0 Temperature dependent protein affecting M2 dsRNA replication Neurexophilin PF06312.12 OWF47045.1 - 1e-08 34.9 0.1 2e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF47045.1 - 0.087 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF3504 PF12012.8 OWF47045.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) p450 PF00067.22 OWF47046.1 - 1.1e-69 235.4 0.0 1.3e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF47047.1 - 9e-106 354.4 0.0 1e-105 354.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF47048.1 - 3.4e-110 369.0 0.0 3.8e-110 368.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF47049.1 - 9.7e-112 374.0 0.0 1.1e-111 373.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DXP_redisom_C PF08436.12 OWF47050.1 - 0.044 13.9 0.6 14 5.9 0.0 3.2 1 1 4 5 5 5 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Hexapep PF00132.24 OWF47050.1 - 0.049 13.4 12.9 0.24 11.2 0.9 3.5 2 1 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) Sushi PF00084.20 OWF47050.1 - 0.06 14.0 3.3 2.2 8.9 0.3 3.5 1 1 2 3 3 3 0 Sushi repeat (SCR repeat) CG-1 PF03859.16 OWF47050.1 - 0.17 11.7 2.2 16 5.3 0.2 3.3 1 1 2 3 3 3 0 CG-1 domain Amidase_5 PF05382.13 OWF47050.1 - 0.3 11.0 14.7 6.1 6.7 1.2 3.5 1 1 1 2 2 2 0 Bacteriophage peptidoglycan hydrolase Cellsynth_D PF03500.13 OWF47051.1 - 0.07 13.0 0.5 2.9 7.8 0.2 2.3 1 1 1 2 2 2 0 Cellulose synthase subunit D Sushi PF00084.20 OWF47051.1 - 0.2 12.3 2.4 5 7.8 1.1 3.3 1 1 1 2 2 2 0 Sushi repeat (SCR repeat) Fve PF09259.11 OWF47051.1 - 0.64 10.2 3.5 6.2 7.0 0.2 2.8 1 1 2 3 3 3 0 Fungal immunomodulatory protein Fve Hexapep PF00132.24 OWF47051.1 - 2.8 7.8 17.1 2.5 8.0 1.0 4.0 1 1 3 4 4 4 0 Bacterial transferase hexapeptide (six repeats) DUF1069 PF06370.11 OWF47051.1 - 8.9 5.8 15.9 9.1 5.8 7.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1069) Cellsynth_D PF03500.13 OWF47052.1 - 0.0059 16.5 2.6 0.75 9.7 0.2 2.9 1 1 0 2 2 2 2 Cellulose synthase subunit D Keratin PF02422.16 OWF47052.1 - 1 9.1 15.5 4.6 7.0 1.6 3.1 1 1 2 3 3 3 0 Keratin FG-GAP_2 PF14312.6 OWF47052.1 - 1.2 9.4 12.1 71 3.8 0.6 6.2 1 1 6 7 7 7 0 FG-GAP repeat DUF1069 PF06370.11 OWF47052.1 - 2.5 7.6 16.5 6.8 6.2 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1069) OMP_b-brl PF13505.6 OWF47052.1 - 2.8 8.0 18.1 1.1e+02 2.8 18.1 3.1 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain Cellsynth_D PF03500.13 OWF47053.1 - 0.00088 19.2 3.8 0.46 10.4 1.1 3.3 1 1 1 2 2 2 2 Cellulose synthase subunit D AzlC PF03591.14 OWF47053.1 - 0.063 13.7 3.7 1.4 9.4 0.4 3.0 1 1 1 2 2 2 0 AzlC protein Keratin PF02422.16 OWF47053.1 - 1.4 8.7 17.7 5.9 6.7 2.8 3.5 1 1 4 5 5 5 0 Keratin FG-GAP_2 PF14312.6 OWF47053.1 - 2.2 8.6 15.0 40 4.6 0.6 6.7 1 1 6 8 8 8 0 FG-GAP repeat OMP_b-brl PF13505.6 OWF47053.1 - 2.5 8.2 19.0 27 4.9 4.7 3.3 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain DUF1069 PF06370.11 OWF47053.1 - 7.5 6.1 18.8 11 5.6 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1069) MMR_HSR1 PF01926.23 OWF47054.1 - 6.1e-14 52.1 0.0 9.4e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF47054.1 - 5.2e-09 36.2 0.2 3.9e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OWF47054.1 - 6.9e-05 22.4 0.1 0.00015 21.4 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OWF47054.1 - 0.00019 20.9 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF47054.1 - 0.00024 20.7 0.1 0.0095 15.5 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OWF47054.1 - 0.0055 16.1 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ploopntkinase1 PF18748.1 OWF47054.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Septin PF00735.18 OWF47054.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Septin Dynamin_N PF00350.23 OWF47054.1 - 0.071 13.2 0.1 7.1 6.7 0.2 2.3 1 1 1 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 OWF47054.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 OWF47054.1 - 0.17 12.1 0.1 0.51 10.6 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ACPS PF01648.20 OWF47055.1 - 4.9e-16 58.9 0.0 9.5e-15 54.7 0.0 2.4 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily EAP30 PF04157.16 OWF47056.1 - 2.7e-44 151.2 1.7 3.8e-44 150.7 1.7 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 OWF47056.1 - 9.4e-15 54.6 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DUF1323 PF07037.11 OWF47056.1 - 0.021 15.2 0.1 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) EcKinase PF02958.20 OWF47056.1 - 0.13 11.6 0.1 0.61 9.3 0.0 2.1 3 0 0 3 3 3 0 Ecdysteroid kinase Fib_alpha PF08702.10 OWF47056.1 - 0.13 12.5 3.1 0.24 11.6 1.1 2.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TssO PF17561.2 OWF47056.1 - 0.26 11.4 3.0 0.28 11.3 1.2 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO Methyltransf_32 PF13679.6 OWF47057.1 - 2.3e-10 40.7 14.6 2.8e-10 40.4 7.5 3.3 3 1 0 3 3 3 1 Methyltransferase domain TRM13 PF05206.14 OWF47057.1 - 8.2e-09 35.4 0.6 0.0048 16.5 1.9 3.6 2 1 1 3 3 3 2 Methyltransferase TRM13 Methyltransf_31 PF13847.6 OWF47057.1 - 1.5e-08 34.6 0.1 3.6e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF47057.1 - 5.8e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GST_C_3 PF14497.6 OWF47057.1 - 0.00048 20.3 0.0 0.002 18.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 OWF47057.1 - 0.0027 18.4 0.1 0.0083 16.8 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OWF47057.1 - 0.0036 16.8 0.0 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 OWF47057.1 - 0.013 16.2 0.2 0.064 14.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 OWF47057.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G GST_C PF00043.25 OWF47057.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MH2 PF03166.14 OWF47058.1 - 4.1e-76 255.4 1.2 5.7e-76 254.9 1.2 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 OWF47058.1 - 3.2e-43 146.1 1.4 7.9e-43 144.9 1.4 1.7 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 OWF47058.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 OWF47058.1 - 0.15 12.0 0.3 0.32 11.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Sedlin_N PF04628.13 OWF47059.1 - 7.6e-48 161.9 0.6 8.5e-48 161.8 0.6 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OWF47059.1 - 5e-07 29.7 0.1 6.9e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family PCM1_C PF15717.5 OWF47060.1 - 7.2e-125 418.1 29.6 7.2e-125 418.1 29.6 6.6 3 3 3 7 7 7 2 Pericentriolar material 1 C terminus Homeodomain PF00046.29 OWF47061.1 - 1.5e-23 82.4 3.4 2.6e-23 81.6 3.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF47061.1 - 0.0017 18.2 0.1 0.004 17.0 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain PNISR PF15996.5 OWF47061.1 - 0.047 14.0 10.9 0.082 13.2 10.9 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Sec10 PF07393.11 OWF47061.1 - 0.11 10.9 7.5 0.13 10.6 7.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Pkinase_fungal PF17667.1 OWF47061.1 - 0.25 10.1 4.9 0.32 9.7 4.9 1.1 1 0 0 1 1 1 0 Fungal protein kinase Hydin_ADK PF17213.3 OWF47061.1 - 0.4 10.9 6.4 0.56 10.4 6.4 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 OWF47061.1 - 0.41 10.2 23.3 0.61 9.7 23.3 1.2 1 0 0 1 1 1 0 Spt20 family Zip PF02535.22 OWF47061.1 - 0.76 8.9 6.0 1.1 8.4 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 OWF47061.1 - 0.84 8.4 12.8 1.1 8.0 12.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 OWF47061.1 - 1.3 7.5 13.1 1.5 7.3 13.1 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OWF47061.1 - 1.3 7.7 15.6 1.8 7.2 15.6 1.1 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 OWF47061.1 - 3 6.7 8.4 4 6.3 8.4 1.1 1 0 0 1 1 1 0 Mitoguardin Menin PF05053.13 OWF47061.1 - 3.2 6.0 12.2 4.1 5.6 12.2 1.1 1 0 0 1 1 1 0 Menin SLC12 PF03522.15 OWF47061.1 - 3.3 6.6 12.8 4 6.4 12.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 OWF47061.1 - 5.7 6.7 13.0 7.5 6.3 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 OWF47061.1 - 8.4 4.2 9.9 9.7 4.0 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-H2C2_2 PF13465.6 OWF47062.1 - 9.8e-15 54.2 21.6 2e-09 37.4 0.7 5.1 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47062.1 - 3e-11 43.1 36.3 0.00019 21.7 2.0 5.2 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47062.1 - 3.7e-09 36.7 28.0 0.002 18.8 0.8 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF47062.1 - 2.7e-06 27.2 19.2 0.00013 21.9 2.3 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 OWF47062.1 - 0.00021 20.8 7.7 2 8.1 0.5 4.6 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 OWF47062.1 - 0.0031 18.2 19.4 0.47 11.1 1.2 4.2 3 1 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 OWF47062.1 - 0.0094 16.1 15.4 1.6 8.9 0.7 4.6 3 1 1 4 4 4 1 Zinc ribbon domain FYVE PF01363.21 OWF47062.1 - 0.023 14.9 16.3 17 5.6 16.3 2.8 1 1 0 1 1 1 0 FYVE zinc finger DUF2259 PF10016.9 OWF47062.1 - 0.1 12.5 1.2 0.2 11.6 0.6 1.7 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) DUF2256 PF10013.9 OWF47062.1 - 0.2 11.8 4.4 29 4.9 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 OWF47062.1 - 0.2 12.1 15.6 0.44 11.0 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type ADK_lid PF05191.14 OWF47062.1 - 0.29 11.1 17.6 0.065 13.2 3.2 4.5 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-MYST PF17772.1 OWF47062.1 - 0.3 10.7 11.3 10 5.8 0.0 4.1 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 OWF47062.1 - 0.5 10.7 18.0 0.1 12.9 1.0 3.9 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 OWF47062.1 - 0.91 9.5 11.4 0.61 10.0 0.9 3.4 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PhnA_Zn_Ribbon PF08274.12 OWF47062.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.3 5 0 0 5 5 3 0 PhnA Zinc-Ribbon XPA_N PF01286.18 OWF47062.1 - 3 8.0 14.0 8.5 6.5 0.2 4.4 4 0 0 4 4 4 0 XPA protein N-terminal DUF3268 PF11672.8 OWF47062.1 - 5.3 7.4 8.4 13 6.1 0.6 3.1 2 1 1 3 3 3 0 zinc-finger-containing domain DZR PF12773.7 OWF47062.1 - 7 6.8 13.5 59 3.8 4.5 3.4 1 1 2 3 3 3 0 Double zinc ribbon HypA PF01155.19 OWF47062.1 - 7.4 6.6 10.7 61 3.7 6.6 3.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_5 PF13909.6 OWF47062.1 - 8.2 6.3 17.0 7.2 6.5 0.2 4.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-TRM13_CCCH PF11722.8 OWF47063.1 - 0.0052 16.5 17.9 35 4.3 0.5 6.6 1 1 5 7 7 7 7 CCCH zinc finger in TRM13 protein zf-H2C2_2 PF13465.6 OWF47064.1 - 1.2e-11 44.5 26.6 1.6e-07 31.5 1.1 5.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47064.1 - 8.4e-08 32.3 36.2 0.003 17.9 1.2 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47064.1 - 0.00021 21.8 35.0 0.02 15.7 0.7 5.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-MYST PF17772.1 OWF47064.1 - 1.6 8.4 6.7 3.5 7.3 1.6 3.1 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 OWF47064.1 - 4.7 7.6 12.1 7.7 6.9 0.3 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF47064.1 - 6 7.4 15.2 9.6 6.8 3.6 4.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DNA_pol_A_exo1 PF01612.20 OWF47065.1 - 2.8e-09 36.9 0.0 5.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease LSM14 PF12701.7 OWF47065.1 - 0.0033 17.5 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Scd6-like Sm domain LSM PF01423.22 OWF47065.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 LSM domain EGF_3 PF12947.7 OWF47066.1 - 1.2e-27 95.8 38.9 6.6e-10 39.0 9.4 3.1 3 0 0 3 3 3 3 EGF domain EGF_CA PF07645.15 OWF47066.1 - 2e-14 53.5 35.9 2.7e-08 33.9 4.9 3.2 2 1 0 3 3 3 3 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 OWF47066.1 - 2.4e-13 49.9 32.4 1.8e-05 24.6 3.9 3.2 3 0 0 3 3 3 3 MSP1 EGF domain 1 EGF PF00008.27 OWF47066.1 - 1.6e-09 37.9 37.3 0.00059 20.1 7.0 4.1 3 1 0 3 3 3 3 EGF-like domain cEGF PF12662.7 OWF47066.1 - 1.4e-08 34.5 24.9 0.00055 19.8 5.3 3.9 3 0 0 3 3 3 3 Complement Clr-like EGF-like hEGF PF12661.7 OWF47066.1 - 4.5e-08 33.4 37.8 0.00063 20.3 3.4 5.9 5 2 1 6 6 6 3 Human growth factor-like EGF EB PF01683.18 OWF47066.1 - 1e-05 25.7 29.9 0.05 13.9 3.6 3.3 2 1 1 3 3 3 3 EB module FXa_inhibition PF14670.6 OWF47066.1 - 0.0001 22.5 29.5 0.0047 17.2 9.4 3.4 2 1 1 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 OWF47066.1 - 0.0017 18.6 33.1 0.53 10.7 5.2 4.6 1 1 2 3 3 3 2 EGF-like domain dCMP_cyt_deam_1 PF00383.23 OWF47067.1 - 2.2e-27 94.9 0.0 2.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OWF47067.1 - 2.5e-11 43.5 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase NAD1 PF18778.1 OWF47067.1 - 0.00067 19.8 0.2 0.0011 19.1 0.2 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 OWF47067.1 - 0.00076 19.6 0.1 0.0013 18.9 0.1 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 OWF47067.1 - 0.003 17.6 0.1 0.0049 16.9 0.1 1.3 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 OWF47067.1 - 0.0062 16.7 0.4 0.0091 16.1 0.4 1.4 1 1 0 1 1 1 1 APOBEC3 NAD2 PF18782.1 OWF47067.1 - 0.019 15.1 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 OWF47067.1 - 0.02 14.8 3.5 0.081 12.8 3.5 1.8 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC4 PF18775.1 OWF47067.1 - 0.021 15.0 0.4 0.037 14.2 0.4 1.4 1 0 0 1 1 1 0 APOBEC4 Bd3614-deam PF14439.6 OWF47067.1 - 0.11 12.6 2.9 0.28 11.2 1.2 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase dCMP_cyt_deam_1 PF00383.23 OWF47068.1 - 7e-30 102.9 0.1 1.1e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OWF47068.1 - 1.8e-15 56.9 0.4 2.3e-15 56.6 0.4 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC4_like PF18774.1 OWF47068.1 - 0.0032 17.4 0.5 0.0057 16.6 0.5 1.5 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 OWF47068.1 - 0.014 15.5 0.6 0.026 14.7 0.2 1.6 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 dCMP_cyt_deam_1 PF00383.23 OWF47069.1 - 5.8e-15 55.0 0.5 8.5e-15 54.5 0.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OWF47069.1 - 1.6e-10 40.8 0.2 2e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 OWF47069.1 - 0.0031 17.6 0.6 0.0064 16.6 0.5 1.5 1 1 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 OWF47069.1 - 0.012 15.6 0.2 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 OWF47069.1 - 0.028 14.5 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 OWF47069.1 - 0.04 14.0 0.1 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 SNAD4 PF18750.1 OWF47069.1 - 0.06 13.5 0.6 0.08 13.1 0.6 1.4 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 HMMR_C PF15908.5 OWF47070.1 - 7.6e-46 156.2 12.3 7.6e-46 156.2 12.3 8.6 2 2 4 8 8 8 1 Hyaluronan mediated motility receptor C-terminal ATG16 PF08614.11 OWF47070.1 - 2.4e-05 24.7 21.4 2.4e-05 24.7 21.4 9.8 1 1 5 9 9 9 3 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OWF47070.1 - 0.00035 21.1 7.2 0.00035 21.1 7.2 11.7 1 1 10 12 12 12 5 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 OWF47070.1 - 0.00056 20.0 195.3 0.024 14.7 8.3 11.9 1 1 12 13 13 13 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 OWF47070.1 - 0.0012 18.4 0.6 0.0012 18.4 0.6 9.5 1 1 9 10 10 10 4 Hyaluronan mediated motility receptor N-terminal DUF4164 PF13747.6 OWF47070.1 - 0.0026 18.0 4.8 0.0026 18.0 4.8 12.5 6 2 8 15 15 15 2 Domain of unknown function (DUF4164) GAS PF13851.6 OWF47070.1 - 1.4 8.2 163.8 0.11 11.9 11.7 9.9 1 1 5 8 8 8 0 Growth-arrest specific micro-tubule binding HNH PF01844.23 OWF47070.1 - 1.5 9.1 6.8 0.82 9.9 3.4 2.3 2 0 0 2 2 2 0 HNH endonuclease BACK PF07707.15 OWF47071.1 - 1.5e-21 76.4 3.5 2.8e-21 75.5 3.5 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 OWF47071.1 - 4.2e-18 65.6 0.1 9.3e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 OWF47071.1 - 2.7e-17 62.4 0.6 1.3e-05 25.3 0.0 4.6 4 1 1 5 5 5 3 Kelch motif FMO-like PF00743.19 OWF47071.1 - 2e-15 56.2 0.1 2.5e-11 42.7 0.0 2.3 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like Kelch_1 PF01344.25 OWF47071.1 - 4.4e-15 55.0 0.6 5.7e-07 29.0 0.0 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OWF47071.1 - 7.2e-12 44.8 1.2 0.00044 20.1 0.5 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 OWF47071.1 - 2.4e-09 37.0 0.1 5.6e-05 23.1 0.0 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain K_oxygenase PF13434.6 OWF47071.1 - 1.6e-07 30.8 0.0 7.6e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OWF47071.1 - 2.2e-07 30.4 0.0 1.4e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Kelch_3 PF13415.6 OWF47071.1 - 2.1e-06 27.9 0.2 0.017 15.4 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF47071.1 - 0.0063 16.5 6.6 0.13 12.2 0.1 4.0 4 0 0 4 4 4 1 Kelch motif FMO-like PF00743.19 OWF47072.1 - 1e-43 149.6 0.1 1.1e-27 96.7 0.1 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF47072.1 - 2e-14 53.6 0.0 1.9e-11 43.8 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF47072.1 - 1.3e-10 41.0 0.0 1.5e-08 34.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OWF47072.1 - 5.6e-08 32.4 0.0 6.7e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF47072.1 - 3.8e-07 30.2 0.0 0.14 12.1 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF47072.1 - 0.0011 19.1 0.1 0.0033 17.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Arfaptin PF06456.13 OWF47074.1 - 0.00077 19.1 1.2 0.0017 18.0 1.2 1.5 1 0 0 1 1 1 1 Arfaptin-like domain CaM_bdg_C0 PF10562.9 OWF47074.1 - 0.045 13.8 0.4 0.16 12.1 0.4 2.0 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit PG_binding_2 PF08823.11 OWF47074.1 - 0.062 13.6 3.4 0.076 13.3 0.1 2.8 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Transglut_core PF01841.19 OWF47074.1 - 0.067 13.6 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily RRM_1 PF00076.22 OWF47075.1 - 7.7e-12 44.9 0.1 1.6e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_Eps PF04627.13 OWF47076.1 - 4.2e-20 71.5 0.1 5.3e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Glycos_transf_2 PF00535.26 OWF47077.1 - 7e-22 78.0 0.0 9.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OWF47077.1 - 7e-07 29.4 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OWF47077.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pyr_redox_2 PF07992.14 OWF47078.1 - 7.2e-43 146.9 0.0 9.4e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 OWF47078.1 - 5.7e-12 46.1 10.5 4e-09 36.9 0.2 3.3 2 1 1 3 3 3 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 OWF47078.1 - 2.2e-09 37.8 0.2 3.5e-08 33.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF47078.1 - 9.5e-07 28.9 0.1 0.0049 16.9 0.2 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OWF47078.1 - 1.4e-05 24.6 0.3 4.7e-05 22.9 0.2 1.7 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OWF47078.1 - 5.4e-05 22.6 0.0 0.00029 20.2 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 OWF47078.1 - 6.5e-05 23.4 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.14 OWF47078.1 - 0.00022 20.0 0.1 0.016 14.0 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 OWF47078.1 - 0.00024 20.8 1.8 0.31 10.6 0.1 3.4 2 2 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OWF47078.1 - 0.001 18.3 0.0 0.18 10.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Deltameth_res PF16020.5 OWF47079.1 - 3.3e-05 23.7 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Deltamethrin resistance Radial_spoke_3 PF06098.11 OWF47080.1 - 0.12 11.6 21.4 0.89 8.8 6.1 2.6 1 1 2 3 3 3 0 Radial spoke protein 3 NusB PF01029.18 OWF47080.1 - 9.9 6.4 12.1 40 4.5 3.9 2.4 1 1 1 2 2 2 0 NusB family IncE PF17627.2 OWF47081.1 - 0.26 11.3 7.3 0.44 10.6 7.3 1.4 1 1 0 1 1 1 0 Inclusion membrane protein E DUF3149 PF11346.8 OWF47081.1 - 1.9 8.2 7.8 9.8 5.9 0.1 4.0 3 2 2 5 5 5 0 Protein of unknown function (DUF3149) HGWP PF03578.15 OWF47081.1 - 3.1 7.4 8.1 92 2.7 0.0 4.4 5 0 0 5 5 5 0 HGWP repeat DUF2273 PF10031.9 OWF47081.1 - 3.2 7.9 11.6 16 5.6 2.3 3.3 1 1 2 3 3 3 0 Small integral membrane protein (DUF2273) zf-B_box PF00643.24 OWF47082.1 - 0.00032 20.8 12.7 0.00062 19.9 12.7 1.5 1 0 0 1 1 1 1 B-box zinc finger Reg_prop PF07494.11 OWF47082.1 - 0.0033 17.5 1.5 0.14 12.5 0.1 3.4 4 0 0 4 4 4 1 Two component regulator propeller NHL PF01436.21 OWF47082.1 - 0.0044 17.0 0.4 0.017 15.1 0.1 2.2 2 0 0 2 2 2 1 NHL repeat DUF5018 PF16410.5 OWF47082.1 - 0.0055 15.5 0.7 0.26 9.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5018) SHE3 PF17078.5 OWF47082.1 - 0.014 15.1 4.9 0.037 13.7 4.9 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 SGL PF08450.12 OWF47082.1 - 0.02 14.5 0.4 0.98 9.0 0.0 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF3659 PF12396.8 OWF47082.1 - 0.075 13.0 0.8 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) FliJ PF02050.16 OWF47082.1 - 0.14 12.4 6.4 0.062 13.5 3.6 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein DegS PF05384.11 OWF47082.1 - 0.5 9.8 7.6 2.6 7.5 1.6 2.4 2 0 0 2 2 2 0 Sensor protein DegS zf-H2C2_2 PF13465.6 OWF47084.1 - 2.9e-33 112.8 13.5 1.9e-05 24.8 0.9 8.5 7 1 1 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47084.1 - 1e-18 66.6 48.9 0.00072 19.9 3.0 8.6 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47084.1 - 3.4e-15 55.4 46.1 0.022 15.6 0.5 8.6 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF47084.1 - 2.3e-07 30.4 0.4 2.3e-07 30.4 0.4 6.6 8 0 0 8 8 8 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 OWF47084.1 - 3.8e-07 30.3 35.6 0.044 14.1 0.1 5.6 3 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding AT_hook PF02178.19 OWF47084.1 - 8.3e-06 25.1 87.8 0.24 11.4 1.5 11.0 10 0 0 10 10 10 9 AT hook motif zf-C2H2_6 PF13912.6 OWF47084.1 - 4.4e-05 23.3 0.2 4.4e-05 23.3 0.2 6.1 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF47084.1 - 0.0013 18.4 1.7 0.0013 18.4 1.7 4.4 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 OWF47084.1 - 1.4 9.2 14.2 7.9 6.9 6.1 2.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon MIEAP PF16026.5 OWF47086.1 - 9.2e-29 101.1 0.0 9.2e-29 101.1 0.0 2.9 2 1 1 3 3 3 1 Mitochondria-eating protein TSC22 PF01166.18 OWF47086.1 - 0.0023 18.2 0.6 0.0023 18.2 0.6 3.8 3 1 2 5 5 5 1 TSC-22/dip/bun family gpW PF02831.15 OWF47086.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 gpW ADIP PF11559.8 OWF47086.1 - 0.15 12.1 37.5 0.98 9.5 4.8 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Dioxygenase_N PF04444.14 OWF47086.1 - 0.15 11.9 0.4 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Catechol dioxygenase N terminus DUF1664 PF07889.12 OWF47086.1 - 0.16 12.0 17.2 0.11 12.5 1.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Phasin PF05597.11 OWF47086.1 - 0.17 11.9 12.8 0.73 9.8 0.2 3.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FapA PF03961.13 OWF47086.1 - 0.28 9.7 24.9 0.018 13.7 18.4 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Filament PF00038.21 OWF47086.1 - 0.3 10.6 40.5 0.043 13.4 11.2 3.2 2 2 1 3 3 3 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 OWF47086.1 - 0.43 10.8 38.1 0.11 12.7 5.4 3.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 OWF47086.1 - 2.3 8.4 33.2 0.52 10.5 6.8 2.9 2 1 0 2 2 2 0 Tropomyosin like DUF812 PF05667.11 OWF47086.1 - 4.4 6.1 32.7 0.018 14.0 3.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF812) MbeD_MobD PF04899.12 OWF47086.1 - 7 6.8 10.6 6.4 7.0 2.5 4.0 3 1 1 4 4 4 0 MbeD/MobD like APG6_N PF17675.1 OWF47086.1 - 7.2 7.1 36.0 0.24 11.9 5.2 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 OWF47086.1 - 7.7 6.6 36.0 3.9 7.5 6.3 3.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus JIP_LZII PF16471.5 OWF47086.1 - 8.5 6.6 22.5 0.36 11.0 2.4 3.3 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II T3SSipB PF16535.5 OWF47086.1 - 8.5 6.8 14.4 2.3 8.7 3.4 2.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB ZapB PF06005.12 OWF47086.1 - 8.6 6.9 33.5 22 5.6 11.7 4.0 1 1 2 3 3 3 0 Cell division protein ZapB MIEAP PF16026.5 OWF47087.1 - 4.4e-30 105.4 2.4 6.1e-30 104.9 0.0 2.0 2 0 0 2 2 2 1 Mitochondria-eating protein CCDC144C PF14915.6 OWF47087.1 - 0.00067 18.9 14.2 0.0028 16.8 10.5 2.4 2 1 1 3 3 3 1 CCDC144C protein coiled-coil region Fungal_TACC PF12709.7 OWF47087.1 - 0.015 15.7 13.3 0.064 13.7 6.1 3.4 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Tho2 PF11262.8 OWF47087.1 - 0.017 14.4 9.3 0.019 14.1 7.5 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Golgin_A5 PF09787.9 OWF47087.1 - 0.029 13.8 10.1 0.012 15.1 7.4 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 CCD48 PF15799.5 OWF47087.1 - 0.042 12.2 0.5 0.057 11.7 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Cep57_CLD_2 PF14197.6 OWF47087.1 - 0.078 13.1 6.4 0.33 11.1 6.4 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 SAS4 PF15460.6 OWF47087.1 - 0.089 12.9 0.5 0.089 12.9 0.5 3.7 4 1 1 5 5 4 0 Something about silencing, SAS, complex subunit 4 DUF4407 PF14362.6 OWF47087.1 - 0.54 9.6 5.1 0.91 8.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 OWF47087.1 - 0.6 10.2 19.3 1.1 9.3 3.9 3.0 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein YlqD PF11068.8 OWF47087.1 - 0.65 10.4 8.4 26 5.2 8.6 2.2 2 0 0 2 2 2 0 YlqD protein Uso1_p115_C PF04871.13 OWF47087.1 - 0.77 10.1 13.4 1.4 9.3 12.5 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 OWF47087.1 - 0.85 10.3 9.4 2 9.1 9.4 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FapA PF03961.13 OWF47087.1 - 1.1 7.8 6.3 2 6.9 6.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 OWF47087.1 - 1.7 9.3 7.7 24 5.7 5.5 2.8 2 1 0 2 2 2 0 Initiation control protein YabA BST2 PF16716.5 OWF47087.1 - 2.1 9.0 8.6 4 8.1 0.8 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF3847 PF12958.7 OWF47087.1 - 3.8 7.7 9.2 0.76 9.9 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) SlyX PF04102.12 OWF47087.1 - 3.8 8.2 7.8 15 6.3 0.6 2.7 1 1 1 2 2 2 0 SlyX DUF4337 PF14235.6 OWF47087.1 - 4.3 7.4 11.7 31 4.6 11.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DivIC PF04977.15 OWF47087.1 - 5 7.0 8.5 9.4 6.1 2.8 2.5 2 0 0 2 2 2 0 Septum formation initiator Csm1_N PF18504.1 OWF47087.1 - 5.3 7.5 11.6 5.8 7.3 1.6 2.6 2 1 0 2 2 2 0 Csm1 N-terminal domain Takusan PF04822.13 OWF47087.1 - 5.7 6.9 9.5 0.4 10.6 2.1 2.4 1 1 0 2 2 2 0 Takusan Med21 PF11221.8 OWF47087.1 - 7.9 6.7 10.0 0.51 10.6 2.8 2.2 1 1 1 2 2 2 0 Subunit 21 of Mediator complex RNase_P_pop3 PF08228.11 OWF47088.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.4 2 0 0 2 2 2 0 RNase P subunit Pop3 BK_channel_a PF03493.18 OWF47090.1 - 0.025 14.7 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit WD40 PF00400.32 OWF47092.1 - 2.8e-30 103.9 15.0 4.8e-06 27.2 0.0 10.7 11 0 0 11 11 10 5 WD domain, G-beta repeat EF-hand_1 PF00036.32 OWF47092.1 - 4.8e-11 41.4 1.1 4.1e-05 22.8 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF47092.1 - 4.7e-10 39.2 3.1 8.4e-10 38.4 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 OWF47092.1 - 9.3e-09 35.6 2.0 1.1e-08 35.4 0.6 1.9 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF47092.1 - 1.2e-07 31.1 0.3 0.011 15.6 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain ANAPC4_WD40 PF12894.7 OWF47092.1 - 3.3e-06 27.3 0.2 0.0029 17.9 0.0 5.1 4 2 1 5 5 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 OWF47092.1 - 5.5e-05 22.5 1.0 0.04 13.4 0.3 2.8 2 0 0 2 2 2 2 EF hand Nup160 PF11715.8 OWF47092.1 - 0.00028 19.7 1.3 0.96 8.0 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OWF47092.1 - 0.0027 16.5 0.0 5.9 5.5 0.0 4.3 3 2 2 6 6 6 1 Nup133 N terminal like TolB_like PF15869.5 OWF47092.1 - 0.0098 15.2 0.0 0.041 13.1 0.1 1.9 2 0 0 2 2 2 1 TolB-like 6-blade propeller-like Tap-RNA_bind PF09162.10 OWF47092.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 Tap, RNA-binding p25-alpha PF05517.12 OWF47092.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 p25-alpha EF-hand_4 PF12763.7 OWF47092.1 - 1 9.4 2.9 2.9 7.9 0.3 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand CH PF00307.31 OWF47093.1 - 2.1e-18 66.5 0.0 3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 OWF47093.1 - 6.9e-12 44.8 3.6 1.5e-11 43.7 3.6 1.6 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 OWF47093.1 - 0.00025 20.8 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Alpha-amylase PF00128.24 OWF47094.1 - 3.3e-93 312.9 0.0 5.3e-93 312.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OWF47094.1 - 0.00028 20.1 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 OWF47094.1 - 0.0089 16.5 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Col_cuticle_N PF01484.17 OWF47094.1 - 9.1 6.4 6.2 0.91 9.6 1.4 1.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain TPR_16 PF13432.6 OWF47095.1 - 0.00061 20.4 0.5 0.0025 18.4 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF47095.1 - 0.059 13.7 1.7 0.1 12.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 OWF47095.1 - 0.084 13.5 0.4 15 6.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat APOC4 PF15119.6 OWF47095.1 - 0.11 12.7 0.4 0.79 10.0 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein C4 TPR_6 PF13174.6 OWF47095.1 - 0.21 12.3 6.1 3.2 8.6 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Gelsolin PF00626.22 OWF47096.1 - 3.4e-25 87.7 0.4 4.6e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 Gelsolin repeat 7tm_1 PF00001.21 OWF47097.1 - 1.1e-24 87.2 0.2 1.5e-24 86.8 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF47097.1 - 1.6 8.1 21.5 0.69 9.2 3.4 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF47098.1 - 1.5e-17 63.8 11.1 2.3e-17 63.2 11.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 OWF47099.1 - 8.2e-29 99.2 46.1 3.9e-10 39.3 4.2 7.5 6 1 3 9 9 9 7 Leucine rich repeat TIR PF01582.20 OWF47099.1 - 1.4e-16 60.8 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 OWF47099.1 - 1.8e-13 50.6 13.8 0.003 17.5 0.4 4.6 2 2 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF47099.1 - 1.7e-12 47.3 35.8 0.022 15.2 0.9 7.8 5 2 2 8 8 8 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 OWF47099.1 - 4.2e-12 46.7 0.0 8.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF47099.1 - 0.00039 20.0 10.3 0.18 11.3 0.1 4.1 1 1 2 4 4 4 3 Leucine-rich repeat LRRCT PF01463.24 OWF47099.1 - 0.037 14.6 0.1 0.1 13.2 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 OWF47099.1 - 0.24 11.5 27.7 8.5 6.7 1.0 8.0 9 0 0 9 9 9 0 Leucine Rich repeat dCMP_cyt_deam_1 PF00383.23 OWF47100.1 - 2e-21 75.8 0.1 2.5e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OWF47100.1 - 1e-10 41.5 0.1 1.3e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 OWF47100.1 - 0.011 15.8 0.2 0.018 15.2 0.2 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 OWF47100.1 - 0.021 14.9 0.3 0.03 14.4 0.3 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 OWF47100.1 - 0.025 14.5 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC2 PF18772.1 OWF47100.1 - 0.052 13.6 0.2 0.078 13.0 0.2 1.2 1 0 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 OWF47100.1 - 0.088 12.9 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 OWF47100.1 - 0.12 12.5 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 OWF47100.1 - 0.17 12.0 5.2 0.56 10.3 1.4 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase dCMP_cyt_deam_1 PF00383.23 OWF47101.1 - 3.8e-10 39.6 0.0 4.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OWF47101.1 - 0.033 14.0 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 OWF47102.1 - 7.2e-11 41.9 0.9 9e-11 41.6 0.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OWF47102.1 - 4.9e-08 32.8 0.1 4.9e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OWF47102.1 - 0.055 13.5 0.1 0.066 13.3 0.1 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase Lipase_GDSL_2 PF13472.6 OWF47103.1 - 0.0042 17.5 0.0 0.0048 17.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family LSDAT_euk PF18139.1 OWF47104.1 - 2.8e-43 148.2 0.0 5.7e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF47104.1 - 2.1e-16 59.8 0.0 2.9e-05 23.4 0.0 3.2 3 0 0 3 3 3 3 SLOG in TRPM, prokaryote FlgD PF03963.14 OWF47104.1 - 0.13 12.6 1.2 0.36 11.2 1.2 1.7 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region TBP PF00352.21 OWF47105.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) PC4 PF02229.16 OWF47106.1 - 1.3e-14 53.5 0.3 1.4e-06 27.8 0.2 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) Pex16 PF08610.10 OWF47108.1 - 5.7e-56 190.0 1.4 6.7e-56 189.8 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF16 PF01519.16 OWF47108.1 - 0.069 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 SNARE PF05739.19 OWF47109.1 - 6.8e-07 29.2 0.0 1.9e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 SNARE domain DUF2207 PF09972.9 OWF47109.1 - 0.061 12.1 0.0 0.069 11.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec20 PF03908.13 OWF47109.1 - 0.063 13.2 0.2 0.081 12.8 0.2 1.2 1 0 0 1 1 1 0 Sec20 Surfac_D-trimer PF09006.11 OWF47109.1 - 0.16 11.9 0.2 1.6 8.7 0.1 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Synaptobrevin PF00957.21 OWF47109.1 - 1.2 9.0 3.7 12 5.8 0.4 2.2 2 0 0 2 2 2 0 Synaptobrevin adh_short PF00106.25 OWF47110.1 - 2.9e-40 137.8 0.5 3.9e-40 137.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF47110.1 - 4.2e-21 75.6 0.0 6.6e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF47110.1 - 3.1e-06 27.2 0.3 0.0049 16.8 0.1 2.4 2 0 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.15 OWF47110.1 - 0.00064 18.9 1.1 0.0025 17.0 1.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OWF47110.1 - 0.014 14.8 0.3 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF47110.1 - 0.14 11.5 0.6 2.6 7.3 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OWF47111.1 - 4.7e-37 127.4 0.1 6.3e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF47111.1 - 8.8e-22 77.8 0.0 1.3e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF47111.1 - 0.00016 21.7 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OWF47111.1 - 0.0028 16.9 0.3 0.011 14.9 0.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TIR PF01582.20 OWF47111.1 - 0.015 15.1 0.1 0.042 13.7 0.1 1.7 2 0 0 2 2 2 0 TIR domain RFX_DNA_binding PF02257.15 OWF47113.1 - 3.3e-17 62.9 0.3 1.3e-16 61.0 0.3 2.1 1 0 0 1 1 1 1 RFX DNA-binding domain DUF4746 PF15928.5 OWF47113.1 - 0.17 11.3 3.7 0.3 10.5 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 OWF47113.1 - 0.26 10.5 2.5 2.2 7.4 2.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Copine PF07002.16 OWF47115.1 - 3.6e-47 160.6 0.0 5.6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OWF47115.1 - 1.5e-13 50.9 0.5 1.1e-08 35.3 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 OWF47115.1 - 1.1e-05 25.6 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 OWF47115.1 - 0.0019 18.5 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain KCNQ_channel PF03520.14 OWF47116.1 - 9.7e-26 90.8 4.6 2.6e-25 89.4 4.6 1.7 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 OWF47116.1 - 2.9e-24 85.6 12.4 4.5e-24 85.0 12.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF47116.1 - 7.7e-12 45.0 6.0 7.7e-12 45.0 6.0 2.5 2 0 0 2 2 2 1 Ion channel GCR1_C PF12550.8 OWF47116.1 - 0.014 15.7 0.3 0.16 12.3 0.1 2.5 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes DUF2798 PF11391.8 OWF47116.1 - 0.016 15.3 1.1 0.016 15.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Sensor PF13796.6 OWF47116.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.1 2 1 0 2 2 2 0 Putative sensor IQ PF00612.27 OWF47116.1 - 0.57 10.1 5.5 0.24 11.3 1.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AgrB PF04647.15 OWF47116.1 - 0.93 8.8 8.2 0.26 10.6 4.8 1.8 2 0 0 2 2 2 0 Accessory gene regulator B Lig_chan PF00060.26 OWF47116.1 - 3.4 7.5 5.5 0.46 10.3 0.6 2.1 2 1 0 2 2 2 0 Ligand-gated ion channel CD225 PF04505.12 OWF47116.1 - 5 7.3 7.1 1.6 8.9 0.1 3.5 4 0 0 4 4 4 0 Interferon-induced transmembrane protein Kinesin PF00225.23 OWF47117.1 - 1.3e-84 284.0 0.2 1.3e-82 277.5 0.1 2.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF47117.1 - 2.6e-42 144.2 0.3 2.1e-41 141.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding FAST_2 PF08368.12 OWF47117.1 - 0.0038 18.0 0.6 5 8.0 0.1 3.7 4 0 0 4 4 3 0 FAST kinase-like protein, subdomain 2 WGR PF05406.15 OWF47117.1 - 0.0075 16.3 0.1 6.9 6.8 0.0 2.8 2 1 1 3 3 2 0 WGR domain YabA PF06156.13 OWF47117.1 - 0.023 15.3 9.3 2.3 8.9 1.2 4.0 3 2 0 3 3 3 0 Initiation control protein YabA Myosin_tail_1 PF01576.19 OWF47117.1 - 0.099 10.4 9.7 0.21 9.3 3.2 2.0 2 0 0 2 2 2 0 Myosin tail DUF2570 PF10828.8 OWF47117.1 - 0.12 12.2 5.3 0.19 11.6 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Filament PF00038.21 OWF47117.1 - 0.15 11.6 11.1 1.5 8.3 1.0 2.2 1 1 0 2 2 2 0 Intermediate filament protein MscS_porin PF12795.7 OWF47117.1 - 0.17 11.4 8.5 0.29 10.6 2.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Herpes_IE2_3 PF03361.14 OWF47117.1 - 0.18 11.7 0.9 0.37 10.7 0.9 1.5 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Tropomyosin_1 PF12718.7 OWF47117.1 - 0.19 11.9 6.7 0.35 11.0 1.1 2.3 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 OWF47117.1 - 0.26 10.1 11.0 4.7 6.0 11.0 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 OWF47117.1 - 0.32 11.2 7.1 0.13 12.5 1.3 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF848 PF05852.11 OWF47117.1 - 0.37 10.9 6.2 0.11 12.6 1.2 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) betaPIX_CC PF16523.5 OWF47117.1 - 0.43 10.4 3.1 8.8 6.2 0.2 2.7 2 0 0 2 2 2 0 betaPIX coiled coil IFT57 PF10498.9 OWF47117.1 - 0.45 9.4 6.8 0.82 8.6 6.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3972 PF13118.6 OWF47117.1 - 0.45 11.0 3.3 0.55 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) EzrA PF06160.12 OWF47117.1 - 0.51 8.4 9.4 1.5 6.9 9.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA CREPT PF16566.5 OWF47117.1 - 0.53 10.5 5.1 1.6 8.9 0.7 2.6 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ADIP PF11559.8 OWF47117.1 - 0.57 10.3 13.3 1.7 8.7 3.1 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 OWF47117.1 - 0.73 9.6 5.1 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 OWF47117.1 - 0.75 10.2 7.9 1.8 9.0 7.9 1.6 1 1 0 1 1 1 0 Fez1 TMF_DNA_bd PF12329.8 OWF47117.1 - 0.79 9.8 7.6 0.71 9.9 2.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 OWF47117.1 - 1 9.6 13.0 0.52 10.5 7.3 2.5 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 OWF47117.1 - 1.1 9.9 5.8 7.6 7.2 0.6 2.8 2 1 0 2 2 2 0 SlyX BLOC1_2 PF10046.9 OWF47117.1 - 1.4 9.2 4.4 3.9 7.8 1.1 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 OWF47117.1 - 1.7 8.6 11.6 2.1 8.4 2.5 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 OWF47117.1 - 2.1 8.4 9.8 6.8 6.7 8.2 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Muted PF14942.6 OWF47117.1 - 3.8 7.8 9.3 0.75 10.1 1.3 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 OWF47117.1 - 4.6 7.3 6.1 6.1 6.9 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 OWF47117.1 - 5 5.6 11.7 0.58 8.7 1.1 2.4 2 1 1 3 3 3 0 AAA domain GAS PF13851.6 OWF47117.1 - 5.2 6.4 11.4 10 5.4 4.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 OWF47117.1 - 5.6 7.0 10.0 21 5.2 2.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 OWF47117.1 - 7.7 6.7 11.8 48 4.1 1.9 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YlqD PF11068.8 OWF47117.1 - 9 6.7 8.2 1.5 9.2 2.1 2.1 2 0 0 2 2 2 0 YlqD protein SPATA1_C PF15743.5 OWF47117.1 - 9.6 6.3 11.0 2 8.5 2.0 2.4 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus TTL PF03133.15 OWF47118.1 - 1.2e-58 198.6 0.1 1.8e-58 198.0 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SET PF00856.28 OWF47118.1 - 0.013 15.9 0.1 0.033 14.6 0.1 1.7 1 0 0 1 1 1 0 SET domain MAPKK1_Int PF08923.10 OWF47119.1 - 8.2e-05 22.4 2.2 5.3 6.9 0.0 4.4 1 1 5 6 6 6 5 Mitogen-activated protein kinase kinase 1 interacting Rab5ip PF07019.12 OWF47119.1 - 0.99 10.0 14.0 38 5.0 0.7 4.7 1 1 4 5 5 5 0 Rab5-interacting protein (Rab5ip) FliG_C PF01706.16 OWF47120.1 - 0.017 15.3 0.7 0.046 13.9 0.7 1.7 1 0 0 1 1 1 0 FliG C-terminal domain RsgA_GTPase PF03193.16 OWF47121.1 - 0.0087 16.0 14.5 0.92 9.4 1.9 3.1 1 1 3 4 4 4 4 RsgA GTPase Phage_fiber_C PF06820.12 OWF47121.1 - 0.19 12.1 7.4 5.1 7.5 0.1 4.1 1 1 3 4 4 4 0 Putative prophage tail fibre C-terminus DegS PF05384.11 OWF47121.1 - 0.22 11.0 17.0 3.4 7.2 1.1 4.6 1 1 4 5 5 5 0 Sensor protein DegS OEP PF02321.18 OWF47121.1 - 0.25 11.1 4.2 24 4.7 0.2 3.0 1 1 2 3 3 3 0 Outer membrane efflux protein DUF3828 PF12883.7 OWF47121.1 - 0.39 11.1 4.5 37 4.7 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3828) RcsD_ABL PF16359.5 OWF47121.1 - 1.4 9.0 15.4 3.8 7.7 1.4 3.4 1 1 4 5 5 5 0 RcsD-ABL domain DUF4843 PF16132.5 OWF47121.1 - 7 6.2 20.6 10 5.7 0.8 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4843) OSCP PF00213.18 OWF47122.1 - 3.4e-42 144.5 0.5 4.3e-42 144.1 0.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Ribosomal_S6 PF01250.17 OWF47123.1 - 6.8e-18 64.7 0.0 8.7e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF5552 PF17706.1 OWF47123.1 - 0.058 13.1 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5552) HSP70 PF00012.20 OWF47124.1 - 1.4e-22 79.6 0.0 1.6e-11 43.1 0.0 3.7 2 2 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OWF47124.1 - 2.6e-15 56.1 0.2 0.0055 15.6 0.0 4.2 4 0 0 4 4 4 4 MreB/Mbl protein FGGY_C PF02782.16 OWF47124.1 - 0.00074 19.3 0.1 0.63 9.7 0.1 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_M22 PF00814.25 OWF47124.1 - 0.034 13.9 0.0 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Glycoprotease family ARL17 PF15840.5 OWF47124.1 - 0.18 12.2 0.1 22 5.5 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor-like protein 17 CW_binding_1 PF01473.20 OWF47124.1 - 3.2 8.3 4.8 37 4.9 0.4 2.5 2 0 0 2 2 2 0 Putative cell wall binding repeat Ion_trans PF00520.31 OWF47125.1 - 1.5e-15 57.1 16.6 2.3e-15 56.5 16.6 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 OWF47125.1 - 4.5e-06 27.1 0.1 0.0056 17.2 0.0 2.7 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF47125.1 - 1.1e-05 25.6 1.9 0.054 14.0 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OWF47125.1 - 0.00014 22.0 0.1 0.25 12.0 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OWF47125.1 - 0.00088 19.5 0.1 0.0024 18.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PKD_channel PF08016.12 OWF47125.1 - 0.0024 16.6 14.3 0.01 14.5 9.7 2.3 1 1 0 2 2 2 2 Polycystin cation channel FHA PF00498.26 OWF47126.1 - 9.5e-17 61.1 0.1 2.6e-16 59.7 0.1 1.8 1 1 0 1 1 1 1 FHA domain MFS_1 PF07690.16 OWF47127.1 - 5.5e-20 71.6 14.3 2.9e-15 56.0 3.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily CCDC106 PF15794.5 OWF47127.1 - 1.6 8.4 10.7 2.8 7.6 10.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PNTB PF02233.16 OWF47127.1 - 2.5 6.9 6.3 1.7 7.5 0.8 2.3 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit PUCC PF03209.15 OWF47127.1 - 6.3 5.7 14.4 2.2 7.2 4.2 3.2 2 1 0 2 2 2 0 PUCC protein zf-H2C2_2 PF13465.6 OWF47128.1 - 4.4e-13 49.0 55.7 4.9e-06 26.7 5.7 8.4 8 0 0 8 8 8 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF47128.1 - 2.7e-05 23.8 0.8 2.7e-05 23.8 0.8 7.0 9 0 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF47128.1 - 4e-05 23.8 3.9 4e-05 23.8 3.9 9.2 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47128.1 - 0.00031 21.3 75.4 0.003 18.3 2.7 9.3 9 0 0 9 9 9 4 C2H2-type zinc finger zf-met PF12874.7 OWF47128.1 - 0.0014 18.9 0.8 0.0014 18.9 0.8 7.3 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OWF47128.1 - 0.035 13.9 19.4 0.33 10.7 0.6 4.8 4 0 0 4 4 4 0 zinc-finger C2H2-type AT_hook PF02178.19 OWF47128.1 - 1 9.4 22.2 0.18 11.8 4.5 2.6 2 0 0 2 2 2 0 AT hook motif Cobl PF09469.10 OWF47128.1 - 1.2 9.4 3.3 46 4.4 0.1 3.3 2 1 1 3 3 3 0 Cordon-bleu ubiquitin-like domain DUF3672 PF12421.8 OWF47132.1 - 8.7e-14 51.6 4.8 0.15 12.0 0.0 7.2 1 1 8 9 9 9 6 Fibronectin type III protein FAINT PF04385.15 OWF47132.1 - 0.0039 17.2 11.2 4.4 7.4 0.2 5.7 2 2 4 6 6 6 2 Domain of unknown function, DUF529 Peptidase_C25_C PF03785.14 OWF47132.1 - 3.6 7.5 22.1 2.8 7.8 1.0 5.2 1 1 5 6 6 6 0 Peptidase family C25, C terminal ig-like domain RMI1_C PF16099.5 OWF47132.1 - 5.8 6.8 14.3 40 4.0 0.1 5.8 1 1 4 7 7 7 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Receptor_2B4 PF11465.8 OWF47132.1 - 6.3 7.0 12.0 53 4.1 0.1 6.6 1 1 6 10 10 10 0 Natural killer cell receptor 2B4 FlgD_ig PF13860.6 OWF47132.1 - 9.1 6.2 47.1 3.7 7.5 0.7 9.8 1 1 11 13 13 13 0 FlgD Ig-like domain Cyclin_N PF00134.23 OWF47133.1 - 1e-38 131.9 1.0 1.8e-38 131.2 1.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF47133.1 - 8.1e-19 67.9 0.9 8.1e-19 67.9 0.9 2.3 3 0 0 3 3 3 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.10 OWF47133.1 - 0.0073 16.7 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 K cyclin, C terminal DUF3875 PF12991.7 OWF47134.1 - 0.41 10.6 7.5 61 3.7 0.2 6.3 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3875) DUF3996 PF13161.6 OWF47135.1 - 0.32 10.7 7.5 32 4.2 7.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3996) OMP_b-brl_3 PF14905.6 OWF47135.1 - 1.6 7.7 17.8 7.2 5.5 17.8 1.8 1 1 0 1 1 1 0 Outer membrane protein beta-barrel family DUF3575 PF12099.8 OWF47135.1 - 5 6.4 12.7 34 3.7 11.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3575) DUF481 PF04338.12 OWF47135.1 - 9.7 6.1 9.6 1.7e+02 2.1 9.4 2.4 1 1 0 1 1 1 0 Protein of unknown function, DUF481 DUF3408 PF11888.8 OWF47136.1 - 0.066 13.4 3.7 0.24 11.5 3.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) IL31 PF15209.6 OWF47136.1 - 0.078 12.8 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Interleukin 31 CENP-B_dimeris PF09026.10 OWF47136.1 - 5.1 7.6 8.6 34 4.9 3.6 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BRCT PF00533.26 OWF47137.1 - 1.3e-13 51.1 0.4 2.4e-06 27.8 0.1 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OWF47137.1 - 2.4e-08 34.3 0.2 0.00076 19.8 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Retinal PF15449.6 OWF47137.1 - 0.0017 16.3 33.2 0.021 12.6 17.8 2.1 1 1 1 2 2 2 2 Retinal protein PTCB-BRCT PF12738.7 OWF47137.1 - 0.0056 16.6 0.4 0.061 13.3 0.2 2.5 2 1 0 2 2 2 1 twin BRCT domain BRCT_3 PF18428.1 OWF47137.1 - 0.029 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OWF47137.1 - 0.038 13.9 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Ndc1_Nup PF09531.10 OWF47137.1 - 1.4 7.5 6.8 2.5 6.7 5.7 1.9 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Pro-rich PF15240.6 OWF47137.1 - 4.7 7.5 69.1 2.1 8.6 51.1 2.4 1 1 1 2 2 2 0 Proline-rich Podoplanin PF05808.11 OWF47137.1 - 5.9 7.0 20.0 3 7.9 3.1 4.0 1 1 3 4 4 4 0 Podoplanin Glyco_transf_10 PF00852.19 OWF47138.1 - 1.5e-48 164.9 2.2 2.8e-48 164.0 2.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF47138.1 - 1.8e-13 50.9 2.5 2e-13 50.8 0.0 2.3 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal Pneumo_M2 PF07380.11 OWF47138.1 - 0.0099 16.1 0.1 0.099 12.9 0.0 2.4 2 0 0 2 2 2 1 Pneumovirus M2 protein CBM_6 PF03422.15 OWF47139.1 - 0.024 14.9 0.1 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) Glyco_hydro_18 PF00704.28 OWF47140.1 - 5.8e-95 318.6 0.9 7.7e-95 318.2 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF47140.1 - 1.1e-19 70.4 19.4 1e-12 48.0 5.6 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Fibrinogen_C PF00147.18 OWF47140.1 - 0.13 12.1 1.1 0.28 11.0 0.2 1.9 2 0 0 2 2 2 0 Fibrinogen beta and gamma chains, C-terminal globular domain Nas2_N PF18265.1 OWF47141.1 - 0.00018 21.4 0.1 15 5.5 0.0 3.9 3 0 0 3 3 3 3 Nas2 N_terminal domain DUF4937 PF16291.5 OWF47141.1 - 0.0047 17.1 5.9 32 4.9 0.1 6.2 5 1 0 5 5 5 1 Domain of unknown function (DUF4937 REF PF05755.12 OWF47141.1 - 0.42 10.4 1.4 54 3.5 0.0 3.7 4 2 0 4 4 4 0 Rubber elongation factor protein (REF) AAA_6 PF12774.7 OWF47142.1 - 1.5e-162 540.1 0.3 4.5e-160 532.0 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF47142.1 - 1.5e-147 491.9 6.9 1.5e-147 491.9 6.9 2.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF47142.1 - 1.9e-119 398.5 0.0 4e-119 397.4 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF47142.1 - 1.2e-105 352.6 0.5 2.8e-105 351.4 0.5 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF47142.1 - 1e-89 299.5 3.0 1e-89 299.5 3.0 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF47142.1 - 5.9e-81 270.3 0.1 1.1e-78 262.9 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF47142.1 - 1.9e-59 200.2 0.0 5.1e-59 198.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF47142.1 - 1.9e-49 168.5 8.5 3.7e-49 167.6 8.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF47142.1 - 2e-46 156.9 0.0 5.3e-44 149.1 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF47142.1 - 2e-35 121.7 0.5 7.5e-35 119.8 0.1 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF47142.1 - 4.5e-22 78.6 0.0 1e-06 28.8 0.0 6.8 5 2 1 6 6 6 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OWF47142.1 - 8.5e-19 67.6 0.4 8.7e-18 64.4 0.2 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 OWF47142.1 - 2.4e-06 28.0 0.0 0.19 12.2 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF47142.1 - 3.1e-05 24.3 0.0 0.031 14.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF47142.1 - 4.4e-05 23.9 0.0 0.17 12.2 0.0 3.5 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 OWF47142.1 - 0.00061 20.2 0.8 1.7 9.1 0.0 4.5 5 0 0 5 5 3 1 RNA helicase T2SSE PF00437.20 OWF47142.1 - 0.0061 15.7 0.0 0.024 13.7 0.0 2.0 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OWF47142.1 - 0.018 14.9 0.4 0.18 11.7 0.0 2.7 3 0 0 3 3 2 0 RsgA GTPase AAA_30 PF13604.6 OWF47142.1 - 0.026 14.2 0.3 2.7 7.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OWF47142.1 - 0.046 13.2 0.2 0.59 9.6 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 OWF47142.1 - 0.12 12.9 6.2 1.5 9.4 0.0 4.6 4 0 0 4 4 3 0 AAA domain T3SSipB PF16535.5 OWF47142.1 - 3.1 8.2 13.5 0.87 10.1 1.0 3.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB Prefoldin_2 PF01920.20 OWF47143.1 - 4.6e-18 65.1 11.1 5.5e-18 64.9 11.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit CENP-Q PF13094.6 OWF47143.1 - 0.0017 18.6 4.4 0.018 15.2 0.4 2.0 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit DUF5320 PF17253.2 OWF47143.1 - 0.052 14.6 1.6 0.14 13.3 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) CC2-LZ PF16516.5 OWF47143.1 - 0.75 10.2 10.2 3.5 8.0 0.2 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Ge1_WD40 PF16529.5 OWF47144.1 - 2.8e-142 473.5 0.0 4.5e-142 472.8 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 OWF47144.1 - 0.0014 19.4 0.0 0.18 12.7 0.0 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ATP-gua_PtransN PF02807.15 OWF47144.1 - 0.2 12.1 0.4 39 4.7 0.0 3.5 4 0 0 4 4 4 0 ATP:guanido phosphotransferase, N-terminal domain DUF4503 PF14951.6 OWF47145.1 - 6.5e-34 117.0 15.9 9.1e-27 93.5 5.9 3.6 3 2 1 4 4 4 2 Domain of unknown function (DUF4503) DUF4502 PF14950.6 OWF47145.1 - 4.8e-25 88.8 17.4 9.2e-25 87.9 17.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) A2L_zn_ribbon PF08792.10 OWF47145.1 - 0.0011 18.7 2.7 0.0037 16.9 2.7 1.9 1 0 0 1 1 1 1 A2L zinc ribbon domain DUF2318 PF10080.9 OWF47145.1 - 0.097 12.8 0.2 0.097 12.8 0.2 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) DZR PF12773.7 OWF47145.1 - 0.13 12.3 1.3 0.76 9.8 0.3 2.6 2 0 0 2 2 2 0 Double zinc ribbon Arm PF00514.23 OWF47146.1 - 3.2e-23 81.0 11.8 0.0036 17.3 0.0 9.7 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF47146.1 - 4.9e-13 49.3 3.3 0.00072 19.9 0.2 6.3 3 2 5 8 8 8 4 HEAT repeats HEAT PF02985.22 OWF47146.1 - 6.3e-08 32.2 8.9 0.057 13.7 0.0 7.6 9 0 0 9 9 6 2 HEAT repeat HEAT_EZ PF13513.6 OWF47146.1 - 3.9e-05 24.0 3.6 0.16 12.5 0.0 5.8 8 0 0 8 8 6 1 HEAT-like repeat V-ATPase_H_C PF11698.8 OWF47146.1 - 0.00028 21.0 7.2 1.8 8.7 0.0 4.8 3 1 2 5 5 5 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 OWF47146.1 - 0.00077 18.8 9.9 0.04 13.2 0.9 3.6 1 1 1 3 3 3 2 V-ATPase subunit H Ank_2 PF12796.7 OWF47146.1 - 0.0014 19.2 0.1 0.019 15.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Cnd1 PF12717.7 OWF47146.1 - 0.0094 16.0 5.5 3.4 7.7 1.0 4.1 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF1981 PF09324.10 OWF47146.1 - 0.04 13.8 0.8 1.3 9.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) RICTOR_V PF14668.6 OWF47146.1 - 0.05 13.8 0.2 4.2 7.7 0.0 3.8 3 1 1 4 4 3 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3361 PF11841.8 OWF47146.1 - 0.057 13.4 15.0 0.18 11.7 1.9 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF3361) IFN-gamma PF00714.17 OWF47146.1 - 0.084 12.7 2.4 0.15 11.9 0.9 2.1 1 1 1 2 2 2 0 Interferon gamma Ank PF00023.30 OWF47146.1 - 0.096 13.2 0.0 0.6 10.7 0.0 2.5 1 0 0 1 1 1 0 Ankyrin repeat BAF250_C PF12031.8 OWF47146.1 - 0.47 9.7 7.8 3 7.1 0.1 3.1 4 0 0 4 4 4 0 SWI/SNF-like complex subunit BAF250/Osa Wap1 PF16997.5 OWF47146.1 - 0.76 8.9 7.3 0.13 11.4 1.9 2.2 1 1 1 2 2 2 0 Wap1 domain RasGEF_N_2 PF14663.6 OWF47146.1 - 2.6 8.5 5.9 4.1 7.8 0.3 4.0 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain 7tm_1 PF00001.21 OWF47147.1 - 1.1e-23 84.0 13.1 1.4e-23 83.6 13.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF47147.1 - 1.7e-09 37.4 10.4 3.3e-09 36.5 10.4 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF47147.1 - 2.3e-06 27.4 7.6 2.3e-06 27.4 7.6 2.3 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RL PF17797.1 OWF47147.1 - 0.19 11.7 0.7 0.65 10.0 0.2 2.1 2 0 0 2 2 2 0 RL domain Cadherin_C_2 PF16492.5 OWF47147.1 - 0.25 12.1 4.5 1.7 9.4 0.2 2.8 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal 7tm_1 PF00001.21 OWF47148.1 - 9.3e-25 87.4 15.4 1.2e-24 87.1 15.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF47148.1 - 3.5e-10 39.7 14.9 6e-10 38.9 14.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF47148.1 - 1.4e-07 31.4 8.1 1.4e-07 31.4 8.1 2.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cadherin_C_2 PF16492.5 OWF47148.1 - 0.25 12.1 2.4 2.2 9.1 0.1 2.7 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal DEAD PF00270.29 OWF47149.1 - 1.3e-07 31.6 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OWF47149.1 - 0.012 15.7 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Alkyl_sulf_dimr PF14863.6 OWF47150.1 - 1.8e-46 158.0 0.0 2.9e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 OWF47150.1 - 4.3e-17 62.8 0.2 1.7e-16 60.8 0.1 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 OWF47150.1 - 9.7e-12 45.3 0.5 6.8e-10 39.3 0.0 2.3 1 1 1 2 2 2 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 OWF47150.1 - 2.7e-05 23.8 0.1 5.4e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FeS_assembly_P PF01883.19 OWF47151.1 - 2.1e-18 66.2 0.1 6.3e-18 64.7 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein AlbA_2 PF04326.14 OWF47152.1 - 6.6e-11 42.6 0.0 1.2e-10 41.7 0.0 1.6 1 1 0 1 1 1 1 Putative DNA-binding domain Dehyd-heme_bind PF09098.10 OWF47152.1 - 0.0099 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Metallophos PF00149.28 OWF47153.1 - 5.4e-07 30.3 1.0 1.1e-06 29.4 1.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF47153.1 - 0.00044 20.5 0.1 0.001 19.3 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 OWF47153.1 - 0.00064 19.1 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily Glyco_hydro_38N PF01074.22 OWF47154.1 - 6.8e-76 255.4 3.8 9.4e-76 254.9 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF47154.1 - 2.3e-24 86.7 0.2 1.5e-23 84.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF47154.1 - 2.7e-17 62.7 0.1 5.9e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Herpes_UL35 PF04496.12 OWF47156.1 - 0.4 11.0 1.7 8.7 6.7 0.1 2.7 1 1 1 3 3 3 0 Herpesvirus UL35 family Mic1 PF07035.12 OWF47157.1 - 4.9e-72 240.8 2.6 1e-71 239.8 2.6 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Frigida PF07899.11 OWF47157.1 - 0.063 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Frigida-like protein 7tm_1 PF00001.21 OWF47158.1 - 9.2e-49 166.1 24.5 9.2e-49 166.1 24.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF47158.1 - 8e-08 32.0 21.7 8e-08 32.0 21.7 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF47158.1 - 1.2e-06 28.5 16.0 3.8e-06 26.8 13.1 2.3 2 1 0 2 2 2 1 Olfactory receptor Lipase_GDSL PF00657.22 OWF47159.1 - 4.5e-09 36.6 0.0 5.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OWF47159.1 - 2.3e-07 31.4 0.0 2.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family G6PD_bact PF10786.9 OWF47159.1 - 0.085 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) T2SSF PF00482.23 OWF47159.1 - 0.11 12.5 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Myosin_N PF02736.19 OWF47160.1 - 2.2e-12 46.6 27.8 0.089 12.6 0.1 9.7 4 3 7 11 11 11 5 Myosin N-terminal SH3-like domain ANAPC4_WD40 PF12894.7 OWF47160.1 - 6.8e-07 29.5 1.4 0.76 10.1 0.1 5.1 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain MoaF PF10703.9 OWF47160.1 - 9.6e-06 25.5 30.6 1.2 9.1 0.8 7.0 1 1 5 6 6 6 3 MoaF N-terminal domain Peptidase_M61_N PF17899.1 OWF47160.1 - 2.1e-05 24.6 6.8 0.76 9.8 0.1 5.9 1 1 5 6 6 6 1 Peptidase M61 N-terminal domain DUF2782 PF11191.8 OWF47160.1 - 3.7e-05 23.9 0.0 8.4 6.7 0.0 5.3 1 1 5 6 6 6 0 Protein of unknown function (DUF2782) DNA_ligase_A_M PF01068.21 OWF47160.1 - 6.2e-05 22.7 4.9 1.6 8.3 2.4 5.3 1 1 1 2 2 2 1 ATP dependent DNA ligase domain DUF3332 PF11810.8 OWF47160.1 - 8.2e-05 22.3 17.7 0.033 13.8 2.6 3.4 1 1 3 4 4 4 3 Domain of unknown function (DUF3332) DUF4752 PF15944.5 OWF47160.1 - 0.00011 22.1 6.6 42 4.3 0.0 6.5 3 2 3 7 7 7 0 Domain of unknown function (DUF4752) SCP1201-deam PF14428.6 OWF47160.1 - 0.00025 20.9 11.8 26 4.7 0.6 7.6 3 1 5 8 8 8 0 SCP1.201-like deaminase DUF2917 PF11142.8 OWF47160.1 - 0.0003 20.1 3.1 36 3.8 0.0 7.1 5 1 5 10 10 10 0 Protein of unknown function (DUF2917) Tudor_RapA PF18337.1 OWF47160.1 - 0.00035 20.7 16.4 20 5.5 0.1 8.4 7 2 0 9 9 8 0 RapA N-terminal Tudor like domain PQQ_2 PF13360.6 OWF47160.1 - 0.0004 20.0 4.6 0.001 18.7 4.6 1.8 1 1 0 1 1 1 1 PQQ-like domain NfeD PF01957.18 OWF47160.1 - 0.0022 18.3 0.0 67 4.0 0.0 5.0 1 1 4 5 5 5 0 NfeD-like C-terminal, partner-binding DUF1918 PF08940.11 OWF47160.1 - 0.0028 17.2 11.7 1.9 8.2 0.2 6.2 2 1 4 7 7 7 1 Domain of unknown function (DUF1918) DUF4920 PF16267.5 OWF47160.1 - 0.0036 17.3 1.6 3.9 7.5 0.1 3.6 2 1 2 4 4 4 1 Domain of unknown function (DUF4920) Myco_19_kDa PF05481.12 OWF47160.1 - 0.0044 17.3 22.0 2.9 8.2 0.2 5.1 1 1 3 4 4 4 1 Mycobacterium 19 kDa lipoprotein antigen Rep_fac-A_3 PF08661.11 OWF47160.1 - 0.0047 17.3 17.7 2.3 8.6 0.2 5.9 2 2 5 7 7 7 1 Replication factor A protein 3 Mcl1_mid PF12341.8 OWF47160.1 - 0.0063 15.9 1.1 1 8.6 0.1 2.6 1 1 1 2 2 2 1 Minichromosome loss protein, Mcl1, middle region PH_15 PF17339.2 OWF47160.1 - 0.008 16.1 8.5 0.76 9.7 0.2 3.9 1 1 2 3 3 3 2 PH domain DUF4881 PF16222.5 OWF47160.1 - 0.039 13.8 2.0 4.9 6.9 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4881) FtsK_SpoIIIE_N PF12538.8 OWF47160.1 - 0.093 12.9 15.0 1.4 9.1 1.3 3.6 1 1 1 3 3 3 0 DNA transporter Big_6 PF17936.1 OWF47160.1 - 0.096 13.0 16.1 20 5.6 0.1 5.5 1 1 3 4 4 4 0 Bacterial Ig domain Med6 PF04934.14 OWF47160.1 - 0.11 12.3 2.2 4.1 7.2 2.2 3.1 1 1 0 1 1 1 0 MED6 mediator sub complex component PCC_BT PF18140.1 OWF47160.1 - 0.14 12.5 16.4 4.8 7.5 2.3 4.3 1 1 2 3 3 3 0 Propionyl-coenzyme A carboxylase BT domain BiPBP_C PF06832.12 OWF47160.1 - 0.19 11.8 13.3 4.1 7.5 0.2 4.6 1 1 3 4 4 4 0 Penicillin-Binding Protein C-terminus Family Cadherin PF00028.17 OWF47160.1 - 0.21 12.1 14.7 46 4.6 4.3 5.4 1 1 2 3 3 3 0 Cadherin domain Gmad1 PF10647.9 OWF47160.1 - 0.41 10.4 8.8 15 5.2 0.5 4.0 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Bys1 PF04681.12 OWF47160.1 - 0.46 10.4 16.4 0.99 9.3 2.0 4.1 1 1 2 3 3 3 0 Blastomyces yeast-phase-specific protein OpcA_G6PD_assem PF10128.9 OWF47160.1 - 0.81 9.1 11.0 13 5.2 1.3 4.0 1 1 1 2 2 2 0 Glucose-6-phosphate dehydrogenase subunit DUF4828 PF16110.5 OWF47160.1 - 0.87 10.1 7.4 18 5.9 0.5 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4828) PapC_C PF13953.6 OWF47160.1 - 0.95 9.3 10.7 40 4.1 0.2 5.3 3 2 2 5 5 5 0 PapC C-terminal domain DUF2397 PF09660.10 OWF47160.1 - 1.8 7.4 23.2 1.8 7.4 0.5 5.1 2 2 4 6 6 6 0 Protein of unknown function (DUF2397) LolB PF03550.14 OWF47160.1 - 2.2 8.3 20.2 13 5.8 0.5 4.6 1 1 5 6 6 6 0 Outer membrane lipoprotein LolB DUF960 PF06124.11 OWF47160.1 - 2.5 8.8 20.3 1.9 9.2 0.3 5.1 2 1 3 5 5 5 0 Staphylococcal protein of unknown function (DUF960) LTD PF00932.19 OWF47160.1 - 2.5 8.5 17.8 1.8e+04 -7.1 17.8 4.4 1 1 0 1 1 0 0 Lamin Tail Domain Fil_haemagg PF05594.14 OWF47160.1 - 3.9 8.1 6.8 2.5 8.7 1.2 3.0 2 2 0 2 2 2 0 Haemagluttinin repeat 7tm_1 PF00001.21 OWF47161.1 - 6.6e-36 124.0 18.4 7.7e-36 123.8 18.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF47161.1 - 5.5e-06 25.9 9.8 0.00028 20.3 9.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF47161.1 - 2.7e-05 23.7 14.5 3.8e-05 23.2 14.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Jiraiya PF15038.6 OWF47161.1 - 0.087 12.3 8.8 1.3 8.4 0.9 2.2 1 1 1 2 2 2 0 Jiraiya DNA_pol3_beta_2 PF02767.16 OWF47161.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain MpPF26 PF07666.11 OWF47161.1 - 0.93 9.6 13.4 0.07 13.2 4.9 2.3 1 1 1 2 2 2 0 M penetrans paralogue family 26 SNF PF00209.18 OWF47162.1 - 2.6e-181 603.9 39.8 1e-180 601.9 39.8 1.7 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Cullin_Nedd8 PF10557.9 OWF47163.1 - 1.6e-25 88.9 1.0 2e-25 88.6 1.0 1.1 1 0 0 1 1 1 1 Cullin protein neddylation domain CEP19 PF14933.6 OWF47164.1 - 7.4e-48 163.0 0.4 8.5e-48 162.8 0.4 1.0 1 0 0 1 1 1 1 CEP19-like protein ENT PF03735.14 OWF47165.1 - 5.7e-28 96.8 1.0 1e-27 95.9 1.0 1.5 1 0 0 1 1 1 1 ENT domain Bromodomain PF00439.25 OWF47165.1 - 2e-20 72.7 0.1 6.2e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Linker_histone PF00538.19 OWF47167.1 - 3.6e-29 100.9 2.8 3.6e-29 100.9 2.8 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family Amino_oxidase PF01593.24 OWF47168.1 - 1.4e-70 238.9 0.0 1.7e-70 238.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF47168.1 - 3.4e-10 40.0 0.3 6.7e-10 39.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF47168.1 - 2.6e-06 26.8 1.3 2.6e-06 26.8 1.3 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OWF47168.1 - 7.6e-06 25.3 0.6 2e-05 23.9 0.6 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OWF47168.1 - 1.1e-05 24.9 0.5 0.00032 20.0 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OWF47168.1 - 3.4e-05 23.3 1.0 5.3e-05 22.6 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF47168.1 - 5.5e-05 22.0 1.2 9.8e-05 21.2 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OWF47168.1 - 5.8e-05 22.6 1.0 5.8e-05 22.6 1.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OWF47168.1 - 0.00015 21.5 0.0 0.00043 20.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OWF47168.1 - 0.00048 20.6 0.8 0.00048 20.6 0.8 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF47168.1 - 0.0029 17.6 0.9 0.38 10.7 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OWF47168.1 - 0.0066 15.5 0.5 0.015 14.3 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 OWF47168.1 - 0.018 14.1 0.8 0.028 13.5 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF47168.1 - 0.031 13.6 0.7 0.054 12.8 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OWF47168.1 - 0.13 11.5 2.2 1.3 8.2 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DHC_N1 PF08385.12 OWF47169.1 - 8.7e-168 559.5 8.7 8.7e-168 559.5 8.7 5.4 5 2 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OWF47169.1 - 3.8e-158 525.7 0.4 6.3e-156 518.4 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF47169.1 - 2e-133 445.4 19.2 2e-133 445.4 19.2 7.7 8 2 1 9 9 9 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OWF47169.1 - 2.6e-106 354.7 0.0 1.6e-105 352.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OWF47169.1 - 5.8e-104 347.6 0.0 5.8e-104 347.6 0.0 3.5 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OWF47169.1 - 6.6e-90 300.1 1.1 6.6e-90 300.1 1.1 4.8 6 0 0 6 6 6 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF47169.1 - 2e-74 249.0 6.8 1.1e-72 243.4 0.0 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 OWF47169.1 - 2.4e-59 201.1 8.7 2.4e-59 201.1 8.7 1.7 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OWF47169.1 - 1.2e-58 197.6 0.3 3.9e-58 195.9 0.3 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OWF47169.1 - 1.2e-46 157.7 0.3 4.3e-43 146.2 0.1 3.7 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF47169.1 - 2.9e-32 111.5 0.3 2e-31 108.7 0.3 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF47169.1 - 6.3e-29 100.7 0.0 3.1e-15 56.4 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OWF47169.1 - 1.9e-25 89.0 4.8 3.3e-23 81.8 0.6 3.1 2 0 0 2 2 2 2 AAA+ lid domain AAA PF00004.29 OWF47169.1 - 3.1e-08 34.1 0.6 0.097 13.1 0.0 4.4 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF47169.1 - 4.4e-05 23.9 1.5 0.52 10.7 0.0 5.9 4 1 1 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 OWF47169.1 - 0.00039 21.0 0.0 3.6 8.1 0.0 5.2 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 OWF47169.1 - 0.00079 19.7 5.6 0.11 12.8 0.0 5.3 5 0 0 5 5 4 1 AAA domain T2SSE PF00437.20 OWF47169.1 - 0.0044 16.1 0.6 5.5 6.0 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF815 PF05673.13 OWF47169.1 - 0.011 14.9 0.2 0.53 9.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OWF47169.1 - 0.02 14.6 0.0 3.5 7.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 OWF47169.1 - 0.023 14.9 0.1 2.7 8.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 OWF47169.1 - 0.06 12.7 0.1 43 3.4 0.0 3.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 OWF47169.1 - 0.28 11.4 1.8 6.4 7.0 0.1 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Guanylate_kin PF00625.21 OWF47169.1 - 3.2 7.4 6.4 38 3.9 1.2 3.5 3 0 0 3 3 3 0 Guanylate kinase Glyco_transf_10 PF00852.19 OWF47170.1 - 6.7e-45 153.0 0.8 1.7e-44 151.7 0.8 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF47170.1 - 1.6e-20 73.6 0.9 4.6e-20 72.1 0.9 1.8 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal EAV_GS PF01309.18 OWF47170.1 - 0.053 13.1 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein RVT_1 PF00078.27 OWF47171.1 - 2e-38 132.1 0.1 3.9e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OWF47171.1 - 1.1e-05 25.3 0.3 3.6e-05 23.6 0.3 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OWF47171.1 - 0.0062 16.1 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family I-set PF07679.16 OWF47173.1 - 1.9e-07 31.0 4.5 0.12 12.4 0.0 5.6 6 0 0 6 6 6 3 Immunoglobulin I-set domain Ig_6 PF18452.1 OWF47173.1 - 2.1e-05 24.0 0.9 3.4 7.3 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin domain CBM_14 PF01607.24 OWF47173.1 - 0.29 11.3 75.4 0.049 13.8 8.6 6.5 6 0 0 6 6 6 0 Chitin binding Peritrophin-A domain zf-RING_9 PF13901.6 OWF47174.1 - 3.7e-67 226.3 10.2 8.2e-67 225.2 10.2 1.6 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon RUN PF02759.19 OWF47174.1 - 1.5e-15 57.4 1.4 3.3e-15 56.2 0.6 2.0 2 0 0 2 2 2 1 RUN domain FYVE PF01363.21 OWF47174.1 - 4.7 7.4 15.0 0.12 12.5 0.8 2.7 2 0 0 2 2 2 0 FYVE zinc finger MFS_1 PF07690.16 OWF47175.1 - 2.2e-40 138.7 33.9 3e-35 121.8 10.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF47175.1 - 0.023 13.5 29.0 0.012 14.5 16.6 3.1 1 1 1 3 3 3 0 Sugar (and other) transporter Pam17 PF08566.10 OWF47175.1 - 0.26 11.1 1.0 3.5 7.4 0.6 2.5 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 OWF47176.1 - 2.7e-23 82.5 19.6 6.7e-15 54.9 5.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF47176.1 - 0.059 12.7 10.8 0.095 12.0 10.8 1.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Pam17 PF08566.10 OWF47176.1 - 0.087 12.7 1.7 1.8 8.4 0.9 2.3 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF2140 PF09911.9 OWF47176.1 - 0.12 11.9 0.0 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Importin_rep_4 PF18808.1 OWF47177.1 - 7e-27 93.6 0.3 7e-27 93.6 0.3 5.9 5 2 2 7 7 5 1 Importin repeat HEAT_2 PF13646.6 OWF47177.1 - 1.1e-23 83.4 3.1 1.7e-10 41.1 0.0 8.3 7 2 2 9 9 8 3 HEAT repeats HEAT PF02985.22 OWF47177.1 - 1.9e-17 61.9 10.8 6.5e-05 22.9 0.0 10.8 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 OWF47177.1 - 2e-17 63.3 15.4 1.6e-09 38.1 0.0 9.2 10 2 2 12 12 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OWF47177.1 - 2.6e-13 50.4 11.9 0.00011 22.7 0.0 9.0 4 3 5 9 9 9 2 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 OWF47177.1 - 7.1e-12 45.4 4.6 1.1e-11 44.8 0.6 3.4 4 0 0 4 4 4 1 Importin repeat 6 Cnd1 PF12717.7 OWF47177.1 - 1.4e-10 41.5 3.6 3.7e-05 23.8 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 OWF47177.1 - 3.1e-08 33.6 0.4 0.0034 17.2 0.0 5.8 6 1 0 6 6 6 1 rRNA processing/ribosome biogenesis Importin_rep_5 PF18816.1 OWF47177.1 - 1.3e-05 25.4 0.1 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 1 Importin repeat MMS19_C PF12460.8 OWF47177.1 - 9.8e-05 21.6 11.6 0.095 11.8 0.5 4.7 4 2 1 5 5 5 3 RNAPII transcription regulator C-terminal Tti2 PF10521.9 OWF47177.1 - 0.00055 19.6 1.0 0.87 9.1 0.0 4.6 4 1 1 5 5 5 1 Tti2 family Arm PF00514.23 OWF47177.1 - 0.003 17.5 3.4 0.62 10.2 0.0 5.5 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 OWF47177.1 - 0.081 12.6 0.2 19 4.9 0.0 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4042) PBP1_TM PF14812.6 OWF47177.1 - 0.8 10.1 7.7 2.2 8.7 7.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4484 PF14831.6 OWF47177.1 - 2.8 7.9 4.8 49 3.9 1.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4484) Pkinase PF00069.25 OWF47178.1 - 4e-74 249.3 0.0 4.7e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF47178.1 - 2.3e-37 128.7 0.0 2.9e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF47178.1 - 1.3e-06 28.0 0.0 6.4e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OWF47178.1 - 0.018 14.0 0.3 0.026 13.5 0.3 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OWF47178.1 - 0.023 14.6 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OWF47178.1 - 0.028 14.0 0.1 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CheW PF01584.19 OWF47178.1 - 0.044 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 CheW-like domain SEA PF01390.20 OWF47179.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 SEA domain SLC3A2_N PF16028.5 OWF47179.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus UL45 PF05473.12 OWF47179.1 - 0.043 13.5 0.0 0.09 12.4 0.0 1.4 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like ABC2_membrane_3 PF12698.7 OWF47179.1 - 0.043 12.9 0.1 0.052 12.6 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3328 PF11807.8 OWF47179.1 - 0.096 12.4 0.1 0.33 10.7 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) ISK_Channel PF02060.15 OWF47179.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel SDF PF00375.18 OWF47181.1 - 1.5e-82 277.7 28.2 1.7e-82 277.5 28.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4271 PF14093.6 OWF47181.1 - 0.22 11.4 8.6 0.078 12.9 2.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4271) SDF PF00375.18 OWF47182.1 - 3.5e-89 299.5 33.2 4.4e-89 299.2 33.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 OWF47183.1 - 9.9e-99 331.0 37.2 1.2e-98 330.7 37.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2157 PF09925.9 OWF47183.1 - 0.21 11.4 5.5 0.67 9.7 0.1 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2626 PF11117.8 OWF47183.1 - 1.4 9.7 6.4 0.21 12.4 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2626) RBP_receptor PF14752.6 OWF47184.1 - 4.6e-102 342.6 14.0 5.3e-102 342.4 14.0 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor DUF2870 PF11069.8 OWF47185.1 - 0.024 15.0 1.1 0.024 15.0 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) zf-HIT PF04438.16 OWF47185.1 - 0.15 11.9 0.6 0.28 11.1 0.6 1.4 1 0 0 1 1 1 0 HIT zinc finger TMEM51 PF15345.6 OWF47185.1 - 0.2 11.5 0.7 0.24 11.2 0.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Flavin_Reduct PF01613.18 OWF47186.1 - 0.038 14.0 0.7 0.25 11.4 0.5 2.1 2 0 0 2 2 2 0 Flavin reductase like domain ENT PF03735.14 OWF47186.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 ENT domain Amino_oxidase PF01593.24 OWF47187.1 - 3.8e-10 39.6 0.0 8.5e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF47187.1 - 2.8e-08 33.9 0.0 5.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OWF47187.1 - 0.00071 18.9 0.0 0.0019 17.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF47187.1 - 0.03 13.6 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF47187.1 - 0.092 12.0 0.0 0.76 9.0 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OWF47187.1 - 0.2 12.3 0.0 0.64 10.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KH_1 PF00013.29 OWF47189.1 - 8.7e-20 70.3 7.3 2.2e-09 37.0 0.3 4.6 4 0 0 4 4 4 2 KH domain KH_2 PF07650.17 OWF47189.1 - 0.0095 15.7 4.7 0.69 9.8 0.1 3.8 2 1 1 3 3 3 2 KH domain TEA PF01285.18 OWF47189.1 - 0.017 15.2 2.2 2 8.6 1.4 2.9 2 1 0 2 2 2 0 TEA/ATTS domain Plant_NMP1 PF06694.11 OWF47189.1 - 0.044 12.9 0.3 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) GHMP_kinases_C PF08544.13 OWF47189.1 - 0.082 13.3 0.2 20 5.7 0.0 3.1 3 0 0 3 3 3 0 GHMP kinases C terminal Img2 PF05046.14 OWF47189.1 - 0.42 10.9 8.3 45 4.4 0.0 4.8 2 2 2 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) Peptidase_S24 PF00717.23 OWF47189.1 - 2.6 8.1 5.8 35 4.4 0.0 3.8 3 2 1 4 4 4 0 Peptidase S24-like DUF885 PF05960.11 OWF47190.1 - 4.2e-132 442.5 0.0 4.8e-132 442.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF885 PF05960.11 OWF47191.1 - 3.6e-124 416.3 0.0 4.1e-124 416.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Ald_deCOase PF11266.8 OWF47191.1 - 0.0033 17.1 1.0 0.034 13.8 0.2 2.2 2 0 0 2 2 2 1 Long-chain fatty aldehyde decarbonylase DUF885 PF05960.11 OWF47192.1 - 1.2e-114 384.9 0.0 1.5e-114 384.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) SYCE1 PF15233.6 OWF47193.1 - 0.00021 21.4 8.9 0.00039 20.5 8.9 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 DUF2722 PF10846.8 OWF47193.1 - 0.0022 17.0 1.7 0.0028 16.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) T7SS_ESX_EspC PF10824.8 OWF47193.1 - 0.0026 18.2 0.4 0.0048 17.3 0.4 1.4 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm DLP_helical PF18709.1 OWF47193.1 - 0.0072 15.6 9.7 0.0092 15.2 9.7 1.0 1 0 0 1 1 1 1 Dynamin-like helical domain Tup_N PF08581.10 OWF47193.1 - 0.022 15.1 11.5 0.027 14.8 1.9 2.4 1 1 1 2 2 2 0 Tup N-terminal YpsA PF06908.11 OWF47193.1 - 0.032 14.2 3.2 0.053 13.5 3.2 1.3 1 0 0 1 1 1 0 YspA SLOG family DUF4795 PF16043.5 OWF47193.1 - 0.079 12.6 7.3 0.1 12.2 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) FapA PF03961.13 OWF47193.1 - 0.11 11.1 8.1 0.13 10.8 8.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SWI-SNF_Ssr4 PF08549.10 OWF47193.1 - 0.25 9.9 6.4 0.31 9.6 6.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF2408 PF10303.9 OWF47193.1 - 0.45 11.1 8.7 3.2 8.3 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TMPIT PF07851.13 OWF47193.1 - 0.81 8.9 6.3 1.1 8.4 6.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 OWF47193.1 - 1 8.2 13.5 2.3 7.0 13.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.24 OWF47193.1 - 1.5 8.7 10.4 0.44 10.5 1.7 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD YabA PF06156.13 OWF47193.1 - 1.5 9.5 8.7 3.6 8.3 0.3 2.2 2 0 0 2 2 2 0 Initiation control protein YabA ACCA PF03255.14 OWF47193.1 - 2.6 7.9 9.6 1.4 8.8 1.0 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2018 PF09442.10 OWF47193.1 - 3.8 8.5 7.9 1.9 9.5 3.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) ZapB PF06005.12 OWF47193.1 - 5.9 7.4 11.8 16 6.1 4.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 OWF47193.1 - 8.6 6.7 12.4 3.6 7.9 2.7 3.0 1 1 2 3 3 3 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 OWF47193.1 - 9.8 6.4 11.3 21 5.3 0.6 2.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1126 PF06565.12 OWF47194.1 - 7.6e-104 340.7 3.4 1.8e-34 117.7 0.0 4.4 3 1 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 OWF47194.1 - 6.3e-05 23.3 0.0 0.55 10.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF47194.1 - 0.0011 18.8 0.4 3.7 7.7 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OWF47194.1 - 0.0014 18.0 0.0 0.74 9.5 0.0 3.2 3 0 0 3 3 3 2 EF hand Skp1 PF01466.19 OWF47194.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain SH3_18 PF18354.1 OWF47195.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 CarS bacterial SH3 domain PDZ PF00595.24 OWF47196.1 - 3.4e-11 43.3 0.0 5.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 OWF47196.1 - 8.8e-11 42.8 1.4 8.8e-11 42.8 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 OWF47196.1 - 0.0037 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF47196.1 - 0.03 14.6 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain p450 PF00067.22 OWF47197.1 - 7e-07 28.3 0.0 7.9e-07 28.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_54 PF04666.13 OWF47198.1 - 5.6e-75 251.9 1.7 1e-74 251.1 1.7 1.4 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Totivirus_coat PF05518.11 OWF47198.1 - 1.1 7.3 2.0 1.7 6.6 2.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein ABC_tran PF00005.27 OWF47199.1 - 5.5e-13 49.6 0.0 1.1e-12 48.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OWF47199.1 - 1e-10 41.4 16.7 1.4e-10 40.9 16.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 OWF47199.1 - 0.00061 19.7 0.2 0.0011 18.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Mito_carr PF00153.27 OWF47200.1 - 1.1e-55 185.6 1.3 3.6e-21 74.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 OWF47201.1 - 1.5e-51 172.3 5.6 5e-20 71.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BioY PF02632.14 OWF47201.1 - 0.51 10.4 5.5 0.12 12.4 0.9 2.3 3 1 0 3 3 3 0 BioY family Mito_carr PF00153.27 OWF47202.1 - 5.9e-56 186.4 1.6 2e-19 69.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PhyH PF05721.13 OWF47203.1 - 4.8e-18 66.2 0.1 1.3e-17 64.8 0.0 1.8 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Siva PF05458.12 OWF47204.1 - 1e-24 87.1 21.0 4.3e-20 72.1 0.0 2.9 2 1 1 3 3 3 3 Cd27 binding protein (Siva) FHA PF00498.26 OWF47205.1 - 6.1e-15 55.3 0.1 6.1e-15 55.3 0.1 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OWF47205.1 - 5e-09 36.4 0.0 1.6e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Hemerythrin PF01814.23 OWF47205.1 - 0.048 14.3 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain SAM_1 PF00536.30 OWF47206.1 - 1.7e-09 38.0 0.0 2.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF47206.1 - 1.8e-09 37.5 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MFS_1 PF07690.16 OWF47207.1 - 8.1e-20 71.0 18.6 8.1e-20 71.0 18.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 OWF47207.1 - 0.14 10.6 11.3 0.37 9.1 11.3 1.9 1 1 0 1 1 1 0 Transmembrane secretion effector EF-hand_1 PF00036.32 OWF47208.1 - 2.1e-09 36.2 2.6 0.00089 18.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF47208.1 - 1.6e-08 33.8 0.3 0.00028 20.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF47208.1 - 3.5e-08 33.8 0.3 7.5e-08 32.7 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair DHR10 PF18595.1 OWF47208.1 - 7.3e-06 26.0 1.0 1.8e-05 24.7 1.0 1.6 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain EF-hand_5 PF13202.6 OWF47208.1 - 6.7e-05 22.2 2.9 0.00012 21.4 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF47208.1 - 0.00066 19.5 2.1 0.035 14.0 1.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair Phage_GP20 PF06810.11 OWF47208.1 - 0.017 15.0 0.5 0.017 15.0 0.5 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 DivIVA PF05103.13 OWF47208.1 - 0.018 15.1 1.2 0.047 13.8 1.2 1.7 1 0 0 1 1 1 0 DivIVA protein TMF_DNA_bd PF12329.8 OWF47208.1 - 0.023 14.7 3.8 0.058 13.4 3.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.11 OWF47208.1 - 0.035 14.1 1.1 0.035 14.1 1.1 1.6 2 0 0 2 2 1 0 GDP/GTP exchange factor Sec2p ERM PF00769.19 OWF47208.1 - 0.037 13.8 1.6 0.059 13.2 1.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Fib_alpha PF08702.10 OWF47208.1 - 0.065 13.4 1.1 0.12 12.5 0.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 OWF47208.1 - 0.069 12.7 2.4 0.12 11.9 2.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RILP PF11461.8 OWF47208.1 - 0.069 13.4 0.5 0.17 12.1 0.5 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF4407 PF14362.6 OWF47208.1 - 0.12 11.7 2.8 0.2 11.0 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 OWF47208.1 - 0.41 9.2 3.7 0.56 8.8 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HR1 PF02185.16 OWF47208.1 - 1.9 8.7 8.4 0.069 13.3 2.1 2.0 2 1 0 2 2 1 0 Hr1 repeat Ribosomal_60s PF00428.19 OWF47208.1 - 8.7 7.0 16.6 23 5.7 12.6 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein HECT PF00632.25 OWF47209.1 - 4e-73 246.6 0.0 7.6e-73 245.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 OWF47209.1 - 7e-23 80.7 2.7 1.8e-22 79.4 2.7 1.8 1 0 0 1 1 1 1 Mib_herc2 Sad1_UNC PF07738.13 OWF47209.1 - 1.5e-16 60.6 0.0 3.3e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ank_2 PF12796.7 OWF47209.1 - 1.8e-13 50.9 0.0 2e-09 37.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF47209.1 - 6.9e-11 42.2 0.0 1.4e-06 28.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF47209.1 - 1.4e-07 31.2 0.0 0.031 14.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OWF47209.1 - 3.5e-07 30.4 0.0 0.00042 20.6 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OWF47209.1 - 1.2e-06 29.0 0.0 0.00019 21.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) F5_F8_type_C PF00754.25 OWF47209.1 - 2.2e-05 24.6 0.1 4.9e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF148 PF02520.17 OWF47209.1 - 0.11 12.7 0.1 0.45 10.7 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 TIP120 PF08623.10 OWF47209.1 - 0.11 12.2 0.1 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) VPS9 PF02204.18 OWF47210.1 - 1.1e-21 76.9 0.0 2.2e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SH2 PF00017.24 OWF47210.1 - 1.8e-09 37.5 0.0 4.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain RA PF00788.23 OWF47210.1 - 1.4e-08 35.2 0.1 4.7e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_f0 PF16511.5 OWF47210.1 - 0.0088 16.3 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM CH PF00307.31 OWF47211.1 - 2.3e-10 40.6 0.0 5.8e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain SAM_1 PF00536.30 OWF47211.1 - 5.6e-10 39.5 0.0 1.6e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF47211.1 - 6.9e-08 32.5 0.0 2.1e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FTO_CTD PF12934.7 OWF47211.1 - 0.022 14.5 3.4 0.67 9.7 0.9 2.7 2 0 0 2 2 2 0 FTO C-terminal domain FUSC PF04632.12 OWF47211.1 - 0.024 13.2 1.7 0.036 12.6 1.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 OWF47211.1 - 0.2 11.9 0.4 5.5 7.2 0.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_9 PF12781.7 OWF47212.1 - 4.3e-74 248.4 0.1 2.7e-72 242.5 0.0 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 OWF47212.1 - 5.6e-48 163.7 0.0 9.7e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OWF47212.1 - 7.5e-40 136.4 0.0 1.8e-39 135.2 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OWF47212.1 - 1.8e-31 108.7 0.0 1.6e-30 105.7 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OWF47212.1 - 3.7e-13 49.2 0.2 8.5e-13 48.0 0.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor TelA PF05816.11 OWF47212.1 - 0.005 15.9 0.9 0.005 15.9 0.9 1.7 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) DUF948 PF06103.11 OWF47212.1 - 0.11 12.7 0.3 26 5.2 0.0 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF724 PF05266.14 OWF47212.1 - 0.17 11.7 4.8 0.032 14.1 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FapA PF03961.13 OWF47212.1 - 2.1 6.8 5.6 0.63 8.6 0.9 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 OWF47212.1 - 8.1 5.2 12.5 11 4.8 1.4 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein DHR10 PF18595.1 OWF47212.1 - 8.4 6.5 9.1 3.2 7.8 1.0 3.1 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 OWF47212.1 - 8.6 6.8 6.3 35 4.9 0.2 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) AAA_6 PF12774.7 OWF47213.1 - 5.2e-130 433.2 0.2 1.2e-127 425.5 0.0 4.0 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OWF47213.1 - 1.8e-128 429.6 7.5 1.8e-128 429.6 7.5 4.0 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OWF47213.1 - 3.7e-116 388.5 9.0 3.7e-116 388.5 9.0 4.2 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OWF47213.1 - 4.8e-67 226.0 0.0 2.8e-66 223.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OWF47213.1 - 5.3e-46 156.4 0.0 1.6e-37 128.8 0.0 5.1 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_5 PF07728.14 OWF47213.1 - 7.7e-30 103.7 0.0 3.1e-12 46.7 0.0 5.9 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OWF47213.1 - 3.6e-18 65.9 0.0 1.3e-17 64.1 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OWF47213.1 - 6.9e-16 58.8 0.3 0.0074 16.6 0.0 6.2 5 0 0 5 5 5 4 AAA domain MT PF12777.7 OWF47213.1 - 4.5e-14 52.2 6.0 9.3e-14 51.2 6.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 OWF47213.1 - 5.2e-14 52.8 0.0 0.014 15.9 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OWF47213.1 - 2.8e-12 47.3 0.4 0.12 12.9 0.0 6.1 5 0 0 5 5 4 3 AAA domain AAA_33 PF13671.6 OWF47213.1 - 3.9e-12 46.5 0.0 0.0078 16.4 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 OWF47213.1 - 6.6e-12 46.1 0.2 0.49 10.8 0.0 6.7 7 0 0 7 7 6 3 AAA ATPase domain ABC_tran PF00005.27 OWF47213.1 - 2.8e-07 31.1 4.3 0.044 14.3 0.0 5.2 5 0 0 5 5 4 2 ABC transporter Mg_chelatase PF01078.21 OWF47213.1 - 4.5e-07 29.5 1.2 0.28 10.5 0.0 4.8 6 0 0 6 6 4 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 OWF47213.1 - 2.6e-06 26.7 0.0 0.2 10.7 0.0 3.9 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_30 PF13604.6 OWF47213.1 - 3e-06 27.1 0.3 3 7.5 0.0 4.6 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 OWF47213.1 - 7.5e-06 25.8 0.5 0.14 11.9 0.0 5.3 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_24 PF13479.6 OWF47213.1 - 8.1e-06 25.7 0.0 2.5 7.8 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 OWF47213.1 - 9.5e-06 25.3 0.0 0.55 10.0 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_28 PF13521.6 OWF47213.1 - 2.8e-05 24.4 0.1 18 5.5 0.0 5.7 6 0 0 6 6 5 0 AAA domain AAA_19 PF13245.6 OWF47213.1 - 7.3e-05 23.1 0.6 0.16 12.3 0.0 4.9 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 OWF47213.1 - 0.00016 22.1 0.0 3.2 8.2 0.0 5.0 4 0 0 4 4 4 1 RNA helicase Rad17 PF03215.15 OWF47213.1 - 0.00017 21.5 0.0 1.4 8.8 0.0 4.6 4 0 0 4 4 4 1 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 OWF47213.1 - 0.00027 20.4 0.0 4.2 6.7 0.0 3.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_lid_1 PF17857.1 OWF47213.1 - 0.00046 20.4 0.0 0.002 18.3 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain RsgA_GTPase PF03193.16 OWF47213.1 - 0.0015 18.5 2.0 8.9 6.2 0.0 4.3 5 0 0 5 5 3 0 RsgA GTPase NACHT PF05729.12 OWF47213.1 - 0.0023 17.9 1.1 71 3.3 0.0 5.4 6 0 0 6 6 5 0 NACHT domain AAA_25 PF13481.6 OWF47213.1 - 0.0072 15.9 0.1 1 8.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 OWF47213.1 - 0.011 15.5 0.1 0.4 10.4 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OWF47213.1 - 0.011 15.7 0.4 5.3 7.1 0.0 4.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 OWF47213.1 - 0.013 14.8 0.0 9.4 5.5 0.0 4.0 3 0 0 3 3 3 0 Zeta toxin AAA_21 PF13304.6 OWF47213.1 - 0.037 13.8 0.0 20 4.9 0.0 3.4 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 OWF47213.1 - 0.078 12.6 0.5 24 4.4 0.0 4.0 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain DUF2205 PF10224.9 OWF47213.1 - 0.45 10.6 14.1 1.8 8.6 1.4 4.6 4 0 0 4 4 3 0 Short coiled-coil protein ERG4_ERG24 PF01222.17 OWF47214.1 - 4e-147 490.4 14.4 1.2e-146 488.9 14.4 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OWF47214.1 - 0.00013 21.6 2.5 0.00032 20.3 0.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OWF47214.1 - 0.035 14.5 1.2 0.092 13.2 0.1 2.4 2 0 0 2 2 2 0 Phospholipid methyltransferase TP2 PF01254.18 OWF47214.1 - 0.19 12.3 17.4 0.36 11.4 17.4 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 Corona_nucleoca PF00937.18 OWF47214.1 - 0.32 10.0 11.8 0.49 9.4 11.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RSRP PF17069.5 OWF47214.1 - 5.2 6.5 24.3 9.5 5.7 24.3 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Roc PF08477.13 OWF47215.1 - 7.2e-24 84.3 0.0 1.7e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 OWF47215.1 - 4.8e-21 74.3 17.9 1.1e-12 47.5 1.6 5.5 4 2 2 6 6 6 4 Leucine rich repeat Ras PF00071.22 OWF47215.1 - 2e-12 47.0 0.0 5.5e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Ras family LRR_4 PF12799.7 OWF47215.1 - 2.4e-10 40.5 27.2 3.3e-05 24.2 1.6 7.6 6 2 2 8 8 7 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF47215.1 - 1.1e-06 28.6 1.4 1.7e-05 24.8 0.0 2.8 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Arf PF00025.21 OWF47215.1 - 0.003 17.0 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_9 PF14580.6 OWF47215.1 - 0.0069 15.9 4.0 0.14 11.6 0.1 3.3 2 1 1 3 3 3 1 Leucine-rich repeat MMR_HSR1 PF01926.23 OWF47215.1 - 0.0072 16.4 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF47215.1 - 0.022 14.7 0.1 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase LRR_1 PF00560.33 OWF47215.1 - 0.035 14.6 11.7 10 7.1 0.3 6.5 4 1 0 4 4 4 0 Leucine Rich Repeat ABC_tran PF00005.27 OWF47215.1 - 0.067 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter EF-hand_6 PF13405.6 OWF47215.1 - 0.069 13.1 0.1 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain COR PF16095.5 OWF47215.1 - 0.092 12.5 0.0 2.3 8.0 0.0 2.8 3 0 0 3 3 3 0 C-terminal of Roc, COR, domain Gtr1_RagA PF04670.12 OWF47215.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OWF47215.1 - 0.17 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 OWF47215.1 - 0.2 10.8 0.1 1.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) COR PF16095.5 OWF47216.1 - 3.5e-42 144.4 0.3 1.4e-41 142.4 0.0 2.1 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain TIR_2 PF13676.6 OWF47216.1 - 5.7e-24 85.0 2.1 3.9e-12 46.8 0.0 4.2 4 0 0 4 4 4 2 TIR domain TIR PF01582.20 OWF47216.1 - 4.9e-05 23.2 8.5 0.00034 20.5 0.4 2.9 3 0 0 3 3 3 2 TIR domain DUF1863 PF08937.11 OWF47216.1 - 0.00095 19.5 0.2 0.25 11.7 0.0 3.4 2 2 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) DUF3920 PF13058.6 OWF47216.1 - 0.097 12.9 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) Patched PF02460.18 OWF47217.1 - 1e-129 434.0 13.0 1.2e-129 433.8 13.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF47217.1 - 7.4e-30 103.8 5.5 7.4e-30 103.8 5.5 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OWF47219.1 - 1.3e-130 437.0 17.0 1.6e-130 436.6 17.0 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF47219.1 - 3e-37 127.8 6.0 3e-37 127.8 6.0 3.3 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OWF47219.1 - 0.18 9.4 14.0 0.35 8.5 14.0 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TMEMspv1-c74-12 PF11044.8 OWF47219.1 - 1 9.4 5.4 0.3 11.1 0.2 2.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MMPL PF03176.15 OWF47219.1 - 1.6 7.6 30.0 0.42 9.5 3.0 3.0 2 1 1 3 3 3 0 MMPL family Med17 PF10156.9 OWF47220.1 - 3.9e-05 22.5 4.6 0.00012 20.9 1.1 2.3 2 0 0 2 2 2 2 Subunit 17 of Mediator complex Mod_r PF07200.13 OWF47220.1 - 8 6.6 8.7 0.82 9.8 0.2 3.1 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Pecanex_C PF05041.15 OWF47221.1 - 4.7e-33 114.7 0.0 8.2e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) MASE2 PF05230.11 OWF47221.1 - 0.019 15.1 3.6 0.037 14.1 0.0 3.2 3 0 0 3 3 3 0 MASE2 domain FYVE PF01363.21 OWF47222.1 - 3.1e-09 36.8 8.2 3.1e-09 36.8 8.2 2.4 2 0 0 2 2 2 2 FYVE zinc finger zf-B_box PF00643.24 OWF47222.1 - 0.0025 17.9 8.2 0.0025 17.9 8.2 3.1 3 0 0 3 3 3 2 B-box zinc finger DUF2786 PF10979.8 OWF47222.1 - 0.027 14.4 0.1 0.079 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Mt_ATP-synt_D PF05873.12 OWF47222.1 - 1.1 9.1 7.0 1.3 8.8 0.7 2.8 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1664 PF07889.12 OWF47222.1 - 1.9 8.6 5.3 24 5.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ADSL_C PF10397.9 OWF47222.1 - 2.3 8.8 5.7 0.31 11.6 0.2 2.4 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus Fer4_12 PF13353.6 OWF47222.1 - 8.6 6.6 8.5 3.4 8.0 2.0 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Glycos_transf_2 PF00535.26 OWF47223.1 - 1.2e-26 93.6 0.1 1.9e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF47223.1 - 1.2e-22 80.5 4.1 2.9e-22 79.3 4.1 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 OWF47223.1 - 2.1e-05 24.5 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF47223.1 - 0.00017 21.1 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF47223.1 - 0.00043 19.9 0.1 0.0012 18.4 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CDtoxinA PF03498.14 OWF47223.1 - 0.0028 17.3 4.8 0.0046 16.6 1.0 2.4 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain Cornifin PF02389.15 OWF47224.1 - 6e-48 162.5 0.0 7.3e-09 35.9 0.0 6.0 1 1 5 6 6 6 6 Cornifin (SPRR) family UFD1 PF03152.14 OWF47224.1 - 5.6e-15 55.2 12.9 1.5 8.3 0.0 11.1 1 1 9 11 11 11 8 Ubiquitin fusion degradation protein UFD1 Fibrinogen_BP PF08017.11 OWF47224.1 - 0.0086 14.6 0.0 0.032 12.7 0.0 1.7 1 1 0 1 1 1 1 Fibrinogen binding protein UCR_hinge PF02320.16 OWF47224.1 - 0.02 15.1 10.2 2.3e+02 2.1 0.0 8.2 2 2 7 9 9 9 0 Ubiquinol-cytochrome C reductase hinge protein TMEM151 PF14857.6 OWF47225.1 - 8.9e-159 529.0 3.3 8.9e-159 529.0 3.3 1.5 2 0 0 2 2 2 1 TMEM151 family DUF3580 PF12117.8 OWF47225.1 - 0.021 15.0 0.2 11 6.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3580) DUF1456 PF07308.13 OWF47226.1 - 0.061 13.7 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) B5 PF03484.15 OWF47226.1 - 0.11 12.8 0.0 10 6.5 0.0 2.8 2 1 0 2 2 2 0 tRNA synthetase B5 domain Filo_glycop PF01611.16 OWF47226.1 - 0.25 10.3 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein UPF0552 PF10574.9 OWF47228.1 - 1.6e-85 286.0 0.0 2e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin bZIP_1 PF00170.21 OWF47230.1 - 2.4e-10 40.4 12.7 3.6e-10 39.8 12.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF47230.1 - 2.1e-07 30.9 12.6 4e-07 30.0 12.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF47230.1 - 7.8e-06 26.3 11.2 1.4e-05 25.5 11.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-F_leu_zip PF10473.9 OWF47230.1 - 0.0002 21.4 6.4 0.00034 20.6 6.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 OWF47230.1 - 0.0007 20.1 6.8 0.00094 19.7 6.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region GAS PF13851.6 OWF47230.1 - 0.0026 17.2 6.2 0.0037 16.6 6.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding RSF PF14876.6 OWF47230.1 - 0.0052 15.8 0.0 0.0052 15.8 0.0 1.1 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator Macoilin PF09726.9 OWF47230.1 - 0.0067 15.0 3.3 0.0084 14.7 3.3 1.2 1 0 0 1 1 1 1 Macoilin family JIP_LZII PF16471.5 OWF47230.1 - 0.0086 16.2 2.0 0.0086 16.2 2.0 2.2 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II FapA PF03961.13 OWF47230.1 - 0.017 13.8 3.1 0.019 13.6 3.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A KASH_CCD PF14662.6 OWF47230.1 - 0.028 14.2 7.7 0.037 13.9 7.7 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 OWF47230.1 - 0.031 14.5 4.2 0.052 13.8 4.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TLE_N PF03920.15 OWF47230.1 - 0.037 14.1 3.1 0.056 13.5 2.6 1.6 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain TMF_TATA_bd PF12325.8 OWF47230.1 - 0.038 14.2 2.8 0.038 14.2 2.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0449 PF15136.6 OWF47230.1 - 0.042 14.3 4.3 0.062 13.8 4.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Suppressor_APC PF11414.8 OWF47230.1 - 0.21 11.7 0.3 0.21 11.7 0.3 2.3 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Spc24 PF08286.11 OWF47230.1 - 0.55 10.5 7.9 0.073 13.3 2.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Med21 PF11221.8 OWF47230.1 - 0.89 9.8 10.7 0.47 10.7 3.2 2.2 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF4407 PF14362.6 OWF47230.1 - 1.3 8.3 4.8 2.1 7.6 4.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 OWF47230.1 - 3.5 7.7 11.5 42 4.2 11.5 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 OWF47230.1 - 5.3 6.9 9.6 3.7 7.4 1.6 2.2 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 OWF47231.1 - 1.2e-08 34.9 5.4 2.1e-08 34.2 5.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF47231.1 - 4.2e-08 33.1 8.2 9.7e-08 32.0 8.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF47231.1 - 3.3e-07 30.7 8.9 3.6e-07 30.6 8.5 1.4 1 1 0 1 1 1 1 bZIP Maf transcription factor I-set PF07679.16 OWF47233.1 - 5.3e-21 74.5 1.2 7.2e-10 38.8 0.2 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF47233.1 - 2.4e-19 69.7 10.3 1.9e-11 44.4 2.7 4.6 4 1 1 5 5 5 2 Immunoglobulin domain ig PF00047.25 OWF47233.1 - 1.7e-17 63.4 11.3 4.3e-09 36.4 3.3 3.0 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF47233.1 - 9.5e-11 41.9 14.3 3.4e-06 27.3 0.4 3.3 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 OWF47233.1 - 3.4e-08 33.6 8.3 0.00091 19.4 0.9 3.9 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 OWF47236.1 - 2.6e-28 98.4 2.9 1.9e-11 44.4 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF47236.1 - 8e-26 89.9 0.9 6.7e-09 35.7 0.1 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 OWF47236.1 - 9.7e-22 77.0 0.3 6e-09 36.0 0.0 3.7 3 2 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF47236.1 - 1.3e-15 57.5 9.6 6.2e-06 26.5 0.0 4.7 3 2 1 4 4 4 3 Immunoglobulin domain V-set PF07686.17 OWF47236.1 - 5.8e-13 49.0 4.0 0.00031 20.9 0.1 4.2 3 1 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF47236.1 - 4.6e-06 26.1 0.4 0.033 13.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 OWF47236.1 - 0.00018 21.9 3.7 0.17 12.3 0.0 3.9 3 2 1 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 OWF47236.1 - 0.001 18.8 1.5 0.03 14.1 0.0 3.5 4 0 0 4 4 4 1 Adenovirus E3 region protein CR1 C2-set_2 PF08205.12 OWF47236.1 - 0.0012 18.9 0.1 0.65 10.1 0.0 2.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF47236.1 - 0.0052 16.8 0.3 18 5.4 0.3 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 OWF47237.1 - 7.8e-24 84.1 0.2 2.7e-10 40.7 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 OWF47237.1 - 7.4e-22 77.2 1.3 2.6e-10 40.2 0.1 3.6 3 1 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 OWF47237.1 - 4.4e-17 62.0 0.5 5.7e-05 23.2 0.0 4.3 3 2 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF47237.1 - 1.9e-12 47.4 0.7 5.2e-05 23.5 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 OWF47237.1 - 3.8e-07 30.2 2.1 0.014 15.5 0.4 3.6 3 1 1 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF47237.1 - 0.00059 19.9 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain PDEase_I PF00233.19 OWF47238.1 - 2.8e-81 272.7 0.7 4.7e-81 272.0 0.7 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase NHL PF01436.21 OWF47239.1 - 1.1e-13 50.4 0.4 8.5e-06 25.6 0.0 4.0 4 0 0 4 4 4 2 NHL repeat zf-RING_UBOX PF13445.6 OWF47239.1 - 1.8e-08 34.3 7.3 1.8e-08 34.3 7.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 OWF47239.1 - 1.9e-08 34.3 19.6 5.1e-07 29.7 5.9 4.8 5 1 0 5 5 5 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF47239.1 - 1.2e-07 31.5 8.6 1.2e-07 31.5 8.6 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF47239.1 - 3.5e-06 26.8 0.0 0.026 14.1 0.0 3.5 2 2 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4_3 PF13920.6 OWF47239.1 - 7.9e-05 22.4 5.2 7.9e-05 22.4 5.2 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF47239.1 - 0.00021 21.1 7.8 0.00021 21.1 7.8 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF47239.1 - 0.0011 19.2 7.9 0.0011 19.2 7.9 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF47239.1 - 0.0061 16.7 8.5 0.0061 16.7 8.5 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING SdiA-regulated PF06977.11 OWF47239.1 - 0.091 12.0 0.0 5.2 6.2 0.0 3.0 1 1 0 1 1 1 0 SdiA-regulated Sulfotransfer_3 PF13469.6 OWF47240.1 - 4.1e-11 43.7 0.0 1.4e-10 41.9 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF47240.1 - 1.3e-09 38.0 0.6 2.3e-09 37.1 0.6 1.4 1 1 0 1 1 1 1 Sulfotransferase domain 7tm_1 PF00001.21 OWF47241.1 - 1.9e-76 256.9 3.7 2.4e-76 256.6 3.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF47241.1 - 1.5e-20 73.6 19.4 3e-15 56.3 9.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF47241.1 - 9.9e-09 35.2 13.0 9.9e-09 35.2 13.0 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF47241.1 - 1.9e-08 34.4 11.5 1.1e-06 28.6 7.9 2.6 2 1 0 2 2 2 2 Olfactory receptor ISK_Channel PF02060.15 OWF47241.1 - 0.14 11.9 0.4 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Slow voltage-gated potassium channel DUF996 PF06195.13 OWF47241.1 - 6.2 7.1 14.0 0.58 10.4 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF996) Herpes_BLLF1 PF05109.13 OWF47242.1 - 2.2e-06 26.0 66.2 7.1e-05 21.0 26.6 2.0 1 1 1 2 2 2 2 Herpes virus major outer envelope glycoprotein (BLLF1) DUF16 PF01519.16 OWF47242.1 - 0.018 15.5 0.0 1.7 9.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 PARM PF17061.5 OWF47242.1 - 9.6 6.2 37.9 14 5.7 37.9 1.2 1 0 0 1 1 1 0 PARM BLOC1_2 PF10046.9 OWF47244.1 - 2.9e-05 24.3 13.6 3.3 8.1 0.5 4.8 1 1 3 4 4 4 4 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 OWF47244.1 - 0.00024 21.3 3.8 2.3 8.4 0.4 3.2 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family EzrA PF06160.12 OWF47244.1 - 0.022 13.0 0.0 3.3 5.8 0.0 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 OWF47244.1 - 0.029 13.3 0.0 6.5 5.5 0.0 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein SHE3 PF17078.5 OWF47244.1 - 0.15 11.8 11.1 10 5.8 0.3 3.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 LAS2 PF15792.5 OWF47245.1 - 0.15 12.6 4.2 5.6 7.6 0.1 3.5 1 1 2 3 3 3 0 Lung adenoma susceptibility protein 2 LAS2 PF15792.5 OWF47246.1 - 0.07 13.7 4.3 2.1 8.9 0.3 3.3 1 1 3 4 4 4 0 Lung adenoma susceptibility protein 2 DUF2572 PF10833.8 OWF47246.1 - 0.22 11.3 0.1 28 4.4 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2572) SRPRB PF09439.10 OWF47246.1 - 0.76 9.2 6.7 23 4.4 0.3 4.0 1 1 4 5 5 5 0 Signal recognition particle receptor beta subunit Arnt_C PF18583.1 OWF47246.1 - 0.82 9.3 2.6 54 3.5 0.1 3.7 2 1 3 5 5 5 0 Aminoarabinose transferase C-terminal domain RPN5_C PF18098.1 OWF47247.1 - 3.6e-18 65.4 6.7 8.7e-18 64.1 6.7 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 OWF47247.1 - 4.5e-18 65.7 0.4 3.3e-17 62.9 0.1 2.6 2 1 0 2 2 2 1 PCI domain PRC2_HTH_1 PF18118.1 OWF47247.1 - 0.092 13.6 0.3 0.38 11.6 0.3 2.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain FH2 PF02181.23 OWF47249.1 - 3.9e-95 319.1 12.2 7.2e-95 318.2 12.2 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain PDZ_6 PF17820.1 OWF47249.1 - 3e-30 103.8 0.8 1.5e-10 40.7 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 OWF47249.1 - 3e-28 98.0 0.2 1.2e-10 41.6 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OWF47249.1 - 4.5e-21 75.0 0.8 3.7e-06 27.2 0.0 4.0 2 1 1 4 4 4 3 PDZ domain Tricorn_PDZ PF14685.6 OWF47249.1 - 0.00045 20.1 0.5 0.078 12.9 0.0 3.6 3 0 0 3 3 3 1 Tricorn protease PDZ domain Mito_fiss_reg PF05308.11 OWF47249.1 - 0.0024 18.0 1.1 0.008 16.3 1.1 1.9 1 0 0 1 1 1 1 Mitochondrial fission regulator PDZ_4 PF17816.1 OWF47249.1 - 0.012 15.9 1.0 0.66 10.4 0.0 3.4 3 1 1 4 4 4 0 PDZ domain TBCC_N PF16752.5 OWF47249.1 - 0.072 13.5 0.2 2.6 8.5 0.0 2.9 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain CAP_N PF01213.19 OWF47249.1 - 0.27 10.7 9.6 0.86 9.0 9.6 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ArlS_N PF18719.1 OWF47249.1 - 1.2 9.4 5.0 3.3 7.9 0.1 3.6 3 0 0 3 3 3 0 ArlS sensor domain DHHC PF01529.20 OWF47250.1 - 1.2e-34 119.3 3.5 1.2e-34 119.3 3.5 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Tmemb_9 PF05434.11 OWF47250.1 - 0.008 16.1 0.0 0.008 16.1 0.0 2.0 2 0 0 2 2 2 1 TMEM9 DUF4834 PF16118.5 OWF47250.1 - 0.054 14.4 1.0 1.9 9.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMC PF07810.13 OWF47251.1 - 1.3e-69 231.8 22.6 2.1e-36 124.9 6.2 4.1 3 0 0 3 3 3 2 TMC domain COesterase PF00135.28 OWF47252.1 - 1e-129 433.8 0.0 1.3e-129 433.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47252.1 - 2.3e-05 24.3 0.3 0.00015 21.7 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47252.1 - 0.003 17.1 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family TPT PF03151.16 OWF47253.1 - 9.5e-18 64.5 22.3 1.3e-17 64.1 22.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OWF47253.1 - 0.00054 20.1 29.6 0.00094 19.4 11.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 OWF47253.1 - 9.4 6.3 19.7 0.41 10.7 0.5 3.8 2 1 2 4 4 4 0 Putative transmembrane family 234 Gpi1 PF05024.15 OWF47254.1 - 1.1e-59 201.7 9.1 2.4e-59 200.6 9.1 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) fn3_4 PF16794.5 OWF47255.1 - 9.1e-39 131.5 0.0 1.8e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-III type domain fn3 PF00041.21 OWF47255.1 - 0.00025 21.3 0.0 0.00076 19.8 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Radical_SAM PF04055.21 OWF47256.1 - 4.5e-18 66.2 0.0 1.6e-17 64.4 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily HemN_C PF06969.16 OWF47256.1 - 5.2e-10 39.3 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 HemN C-terminal domain Fer4_14 PF13394.6 OWF47256.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Radical_SAM_C PF16199.5 OWF47256.1 - 0.018 15.1 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 Radical_SAM C-terminal domain DuoxA PF10204.9 OWF47257.1 - 4.3e-109 363.8 11.3 5e-109 363.6 11.3 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Adeno_knob PF00541.17 OWF47257.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) RRN3 PF05327.11 OWF47257.1 - 1.2 7.6 2.7 1.7 7.1 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Acyl-ACP_TE PF01643.17 OWF47258.1 - 2.4e-10 40.1 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase zf-H2C2_5 PF13909.6 OWF47259.1 - 7.1e-05 22.5 0.4 0.00015 21.5 0.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc-finger domain SSF PF00474.17 OWF47261.1 - 1.4e-29 103.2 13.3 1.4e-29 103.2 13.3 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family zf-H2C2_2 PF13465.6 OWF47262.1 - 1e-40 136.4 63.2 4e-08 33.3 0.1 10.4 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47262.1 - 1.9e-31 106.8 62.2 2.6e-05 24.4 1.1 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47262.1 - 2.3e-26 90.2 68.8 0.0015 19.2 0.7 9.6 10 0 0 10 10 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF47262.1 - 1.1e-06 28.7 34.4 0.19 12.1 0.0 10.0 8 1 2 10 10 10 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF47262.1 - 2.7e-06 27.6 46.7 0.37 11.3 0.1 10.1 10 1 0 10 10 10 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF47262.1 - 4.2e-06 26.6 58.3 0.024 14.6 0.2 10.1 10 0 0 10 10 10 4 C2H2-type zinc finger zf-Di19 PF05605.12 OWF47262.1 - 0.0001 22.5 43.7 0.0031 17.8 1.4 5.9 5 1 1 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 OWF47262.1 - 0.00025 20.8 19.0 0.0054 16.5 0.7 5.7 2 2 5 7 7 7 2 GAGA factor zf_UBZ PF18439.1 OWF47262.1 - 0.0011 18.5 32.3 1.3 8.7 0.1 8.5 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 OWF47262.1 - 0.0039 17.1 1.4 0.0039 17.1 1.4 5.2 5 2 1 6 6 6 2 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 OWF47262.1 - 0.014 15.5 35.0 2.2 8.5 2.2 6.5 3 2 3 6 6 6 0 Zinc ribbon domain DUF3268 PF11672.8 OWF47262.1 - 0.015 15.6 1.1 0.015 15.6 1.1 4.5 1 1 6 7 7 7 0 zinc-finger-containing domain BolA PF01722.18 OWF47262.1 - 0.031 14.6 5.7 3.8 7.8 0.0 4.5 3 1 1 4 4 4 0 BolA-like protein zinc_ribbon_15 PF17032.5 OWF47262.1 - 0.049 14.4 28.5 0.58 11.0 2.7 5.3 2 1 2 4 4 4 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 OWF47262.1 - 0.37 11.3 0.1 0.37 11.3 0.1 7.8 9 0 0 9 9 9 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_8 PF15909.5 OWF47262.1 - 1.6 9.1 23.7 0.43 10.9 0.5 4.9 2 1 2 5 5 5 0 C2H2-type zinc ribbon Rad50_zn_hook PF04423.14 OWF47262.1 - 6.2 6.7 16.9 3.1 7.7 0.1 4.5 5 0 0 5 5 4 0 Rad50 zinc hook motif YjeF_N PF03853.15 OWF47263.1 - 3.6e-37 127.9 0.0 5.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus nec1 PF10379.9 OWF47266.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.4 1 1 0 1 1 1 0 Virulence protein nec1 Ank_2 PF12796.7 OWF47267.1 - 8.7e-22 77.5 2.4 2.4e-14 53.6 0.5 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF47267.1 - 3.1e-17 60.9 0.8 3.1e-05 24.0 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ion_trans PF00520.31 OWF47267.1 - 4.8e-17 62.0 13.7 9.8e-17 61.0 13.7 1.5 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 OWF47267.1 - 1.4e-16 60.6 0.8 5.3e-06 26.9 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF47267.1 - 2.1e-16 59.7 4.1 1.6e-09 37.8 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF47267.1 - 3.6e-13 49.3 1.9 1.6e-06 28.3 0.1 4.9 5 0 0 5 5 5 2 Ankyrin repeat PKD_channel PF08016.12 OWF47267.1 - 8.7e-07 28.0 8.4 0.0015 17.3 7.8 2.9 1 1 1 2 2 2 2 Polycystin cation channel PNP_UDP_1 PF01048.20 OWF47268.1 - 5e-18 65.2 0.0 5.5e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PDCD2_C PF04194.13 OWF47269.1 - 1.5e-50 171.7 4.1 2.9e-48 164.2 0.4 2.5 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 OWF47269.1 - 6.7e-09 35.7 11.4 6.7e-09 35.7 11.4 2.7 3 0 0 3 3 3 1 MYND finger PITH PF06201.13 OWF47270.1 - 6.1e-43 146.6 0.0 7.7e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain XendoU PF09412.10 OWF47271.1 - 3.7e-78 262.4 3.3 2.6e-77 259.6 3.3 1.9 1 1 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 OWF47271.1 - 0.047 14.0 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial EndoU nuclease CDP-OH_P_transf PF01066.21 OWF47272.1 - 1.2e-14 54.8 0.0 1.2e-14 54.8 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2109 PF09882.9 OWF47272.1 - 0.12 12.3 1.9 0.58 10.2 1.7 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2109) Pkinase PF00069.25 OWF47275.1 - 3.3e-59 200.4 0.0 4.2e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF47275.1 - 3.2e-35 121.7 0.0 4.5e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF47275.1 - 7.8e-09 35.3 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF47275.1 - 0.0045 15.8 0.1 0.0089 14.8 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OWF47275.1 - 0.025 14.2 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Asn_synthase PF00733.21 OWF47276.1 - 1.6e-14 54.4 0.1 1.1e-08 35.1 0.0 3.3 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 OWF47276.1 - 1.2e-07 31.6 0.0 5.3e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OWF47276.1 - 0.00082 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain SurA_N_3 PF13624.6 OWF47276.1 - 0.03 14.1 0.7 0.056 13.2 0.7 1.4 1 0 0 1 1 1 0 SurA N-terminal domain AKAP2_C PF15304.6 OWF47277.1 - 0.0012 18.2 7.6 0.0012 18.2 7.6 10.3 4 2 4 10 10 10 4 A-kinase anchor protein 2 C-terminus Integrase_DNA PF02920.15 OWF47277.1 - 1.3 8.8 5.7 1.8 8.3 0.5 2.7 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase DAPG_hydrolase PF18089.1 OWF47277.1 - 1.5 8.3 5.8 0.5 9.9 2.7 1.7 2 0 0 2 2 2 0 DAPG hydrolase PhiG domain R3H-assoc PF13902.6 OWF47278.1 - 9.5e-21 74.6 3.3 9.5e-21 74.6 3.3 1.6 1 1 1 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 OWF47278.1 - 1.9e-08 34.2 0.0 4.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain YL1 PF05764.13 OWF47278.1 - 0.12 12.5 6.7 0.027 14.6 2.5 1.9 2 0 0 2 2 2 0 YL1 nuclear protein CAP_GLY PF01302.25 OWF47279.1 - 1.5e-67 223.5 8.9 3.6e-24 84.6 0.1 3.3 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.7 OWF47279.1 - 1.2e-12 48.2 0.3 2e-11 44.3 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF47279.1 - 6.9e-11 42.2 0.5 5.6e-05 23.4 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF47279.1 - 3.8e-10 40.1 0.2 4.6e-06 27.1 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF47279.1 - 7.7e-10 38.8 0.6 0.24 11.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OWF47279.1 - 6.1e-08 32.3 0.1 0.26 12.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat EF-hand_1 PF00036.32 OWF47281.1 - 6.8e-17 59.7 16.0 4.5e-07 29.0 0.4 4.6 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 OWF47281.1 - 1.6e-16 60.5 18.2 6.5e-14 52.1 2.5 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF47281.1 - 4.8e-14 51.0 6.6 7.2e-06 25.5 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF47281.1 - 7.3e-14 51.4 10.8 5e-07 29.5 0.8 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF47281.1 - 2.7e-08 32.9 16.4 2.6e-06 26.7 0.2 3.8 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 OWF47281.1 - 0.014 15.7 6.1 0.052 13.9 0.3 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF47281.1 - 0.19 11.7 9.8 0.17 11.9 0.2 3.1 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Cadherin_3 PF16184.5 OWF47282.1 - 9.2e-231 750.1 41.0 1.1e-22 80.1 0.1 12.9 12 0 0 12 12 12 12 Cadherin-like Lectin_C PF00059.21 OWF47282.1 - 1.2e-15 58.2 2.7 3.7e-15 56.6 2.7 1.9 1 0 0 1 1 1 1 Lectin C-type domain Calx-beta PF03160.14 OWF47282.1 - 2.3e-14 53.4 0.0 1.2e-13 51.1 0.0 2.4 1 0 0 1 1 1 1 Calx-beta domain Cadherin_4 PF17803.1 OWF47282.1 - 4.5e-11 43.2 16.6 0.046 14.3 0.1 9.4 9 1 0 9 9 9 4 Bacterial cadherin-like domain Big_9 PF17963.1 OWF47282.1 - 5.4e-11 43.1 35.6 0.00074 20.2 0.8 12.5 12 3 0 12 12 12 3 Bacterial Ig domain SR-25 PF10500.9 OWF47282.1 - 0.28 10.8 30.6 0.021 14.5 16.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADAM_spacer1 PF05986.14 OWF47283.1 - 3.1e-37 127.1 0.0 5.3e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 OWF47283.1 - 1.1e-35 122.8 0.1 1.1e-35 122.8 0.1 2.2 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.19 OWF47283.1 - 9.7e-25 87.6 0.6 9.7e-25 87.6 0.6 2.2 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 OWF47283.1 - 4.8e-17 62.8 2.9 1.5e-16 61.2 2.9 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.19 OWF47283.1 - 1.9e-14 53.6 87.4 4.1e-07 30.1 8.2 7.5 6 1 1 7 7 7 5 Thrombospondin type 1 domain Reprolysin_3 PF13582.6 OWF47283.1 - 3.4e-13 50.2 0.4 3.4e-13 50.2 0.4 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF47283.1 - 6e-10 39.3 1.2 1.5e-09 38.0 1.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF47283.1 - 5.1e-08 32.8 1.1 1e-07 31.8 1.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 OWF47283.1 - 6.1e-08 33.3 9.4 4.8e-07 30.4 9.4 2.8 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Peptidase_M57 PF12388.8 OWF47283.1 - 0.67 9.5 4.1 0.15 11.6 0.4 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase TRAPP PF04051.16 OWF47284.1 - 1.3e-39 135.2 0.1 1.6e-39 134.9 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 OWF47285.1 - 1.7e-25 88.7 15.2 8.1e-06 26.5 0.2 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF47285.1 - 4e-19 68.7 6.9 1.5e-06 28.4 0.2 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF47285.1 - 1.2e-05 25.3 0.8 0.096 12.6 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF47285.1 - 1.2e-05 24.4 1.3 0.08 11.9 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 OWF47285.1 - 0.022 14.7 0.0 9.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat DUF1513 PF07433.11 OWF47285.1 - 0.043 12.9 1.1 0.46 9.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) ELYS-bb PF16687.5 OWF47285.1 - 0.071 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 OWF47285.1 - 0.15 10.7 6.2 2.6 6.6 0.4 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 GSHPx PF00255.19 OWF47286.1 - 1.3e-34 118.0 0.1 2.1e-34 117.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OWF47286.1 - 1.2e-05 25.2 0.0 3.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family SelP_N PF04592.14 OWF47288.1 - 2.6e-08 33.6 0.9 3.8e-08 33.0 0.9 1.4 1 1 0 1 1 1 1 Selenoprotein P, N terminal region Elongin_A PF06881.11 OWF47289.1 - 0.01 16.4 0.1 0.056 14.0 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 OWF47289.1 - 0.01 15.7 0.7 0.01 15.7 0.7 2.5 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 OWF47289.1 - 0.025 14.5 1.7 0.098 12.6 0.3 2.6 2 0 0 2 2 2 0 F-box-like DUF5371 PF17341.2 OWF47289.1 - 0.027 14.7 0.1 0.056 13.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5371) ArAE_1_C PF11728.8 OWF47289.1 - 0.07 13.1 0.2 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain MA3 PF02847.17 OWF47289.1 - 0.13 12.2 1.0 1.5 8.8 0.1 2.8 3 0 0 3 3 3 0 MA3 domain Y_phosphatase PF00102.27 OWF47290.1 - 1.5e-75 253.8 0.7 1.8e-75 253.6 0.7 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF47290.1 - 0.021 15.0 0.2 0.06 13.5 0.2 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF47290.1 - 0.021 14.8 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 OWF47290.1 - 0.044 13.6 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF47291.1 - 4.2e-73 245.8 0.5 1e-40 139.8 0.1 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF47291.1 - 2e-06 28.0 0.7 2.7e-05 24.3 0.0 2.6 2 1 1 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF47291.1 - 0.00019 21.5 0.0 0.00045 20.3 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 OWF47291.1 - 0.0012 18.7 0.1 0.028 14.2 0.0 2.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain UPRTase PF14681.6 OWF47291.1 - 0.04 13.4 0.4 0.079 12.4 0.4 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Y_phosphatase PF00102.27 OWF47293.1 - 1.3e-90 303.1 5.8 2.8e-59 200.5 2.2 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF47293.1 - 4e-05 23.8 0.4 0.00043 20.4 0.0 2.8 2 1 1 3 3 3 1 Inositol hexakisphosphate DSPc PF00782.20 OWF47293.1 - 0.00048 20.0 0.3 0.062 13.1 0.0 2.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF47293.1 - 0.00059 19.9 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Stevor PF17410.2 OWF47293.1 - 0.0052 16.4 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Chs7 PF12271.8 OWF47293.1 - 0.2 11.0 0.7 0.46 9.8 0.7 1.5 1 0 0 1 1 1 0 Chitin synthase export chaperone DUF2627 PF11118.8 OWF47293.1 - 0.27 11.8 0.6 0.55 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DEAD PF00270.29 OWF47294.1 - 3.6e-06 26.8 0.0 4.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Arb1 PF09692.10 OWF47294.1 - 0.093 11.9 0.4 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RNB PF00773.19 OWF47295.1 - 1.3e-65 221.8 0.1 1.3e-65 221.8 0.1 2.9 2 2 0 2 2 2 1 RNB domain AAA_12 PF13087.6 OWF47295.1 - 5.5e-49 166.5 1.7 5.5e-49 166.5 1.7 2.8 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 OWF47295.1 - 4.3e-40 138.2 0.0 4.3e-40 138.2 0.0 7.2 3 1 3 7 7 7 1 AAA domain AAA_19 PF13245.6 OWF47295.1 - 7.4e-06 26.4 0.0 0.00017 21.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 OWF47295.1 - 0.0029 17.4 0.1 0.013 15.3 0.1 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Arc_PepC PF06819.11 OWF47295.1 - 0.014 15.5 1.8 0.061 13.5 0.1 2.9 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain Rrp44_CSD1 PF17216.3 OWF47295.1 - 0.016 14.9 1.0 0.1 12.3 0.0 2.9 3 0 0 3 3 3 0 Rrp44-like cold shock domain AAA_22 PF13401.6 OWF47295.1 - 0.035 14.4 0.0 0.4 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNB PF00773.19 OWF47296.1 - 3.1e-72 243.7 0.1 6.3e-72 242.6 0.1 1.6 1 0 0 1 1 1 1 RNB domain AAA_12 PF13087.6 OWF47296.1 - 1.7e-43 148.6 0.0 1.1e-42 146.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OWF47296.1 - 8.4e-39 133.9 0.5 3.5e-38 131.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF47296.1 - 3.7e-12 46.3 0.0 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OWF47296.1 - 4.8e-07 30.2 0.0 1.6e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OWF47296.1 - 3e-05 23.9 0.1 0.21 11.3 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OWF47296.1 - 0.00053 19.3 0.0 0.19 10.9 0.0 3.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OWF47296.1 - 0.0026 18.0 0.0 0.025 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain OB_Dis3 PF17849.1 OWF47296.1 - 0.0062 16.5 0.0 0.04 13.9 0.0 2.4 1 1 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) DEAD PF00270.29 OWF47296.1 - 0.044 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 OWF47296.1 - 0.071 12.9 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 OWF47296.1 - 0.1 12.0 0.2 0.24 10.8 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein Nuclease_act PF08133.11 OWF47296.1 - 0.13 12.4 0.1 0.49 10.7 0.1 2.0 1 0 0 1 1 1 0 Anticodon nuclease activator family ATPase PF06745.13 OWF47296.1 - 0.14 11.5 0.1 0.45 9.8 0.1 1.8 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 OWF47296.1 - 0.15 11.9 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 OWF47296.1 - 0.17 11.9 0.4 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 OWF47296.1 - 0.93 9.0 5.4 19 4.7 0.3 3.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain RNB PF00773.19 OWF47297.1 - 5.3e-69 233.0 0.2 1.5e-68 231.6 0.2 1.9 1 0 0 1 1 1 1 RNB domain AAA_12 PF13087.6 OWF47297.1 - 1.7e-46 158.4 0.3 5.7e-46 156.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OWF47297.1 - 1.7e-40 139.5 0.1 1.7e-40 139.5 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OWF47297.1 - 4.2e-11 42.9 0.0 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OWF47297.1 - 1.5e-06 28.6 0.1 5.6e-06 26.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OWF47297.1 - 3.6e-05 23.6 0.1 0.3 10.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OWF47297.1 - 6e-05 22.4 1.2 0.14 11.4 0.0 3.3 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.6 OWF47297.1 - 6.4e-05 22.5 0.0 0.00068 19.1 0.0 2.5 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 OWF47297.1 - 0.00015 22.1 0.0 0.0031 17.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OWF47297.1 - 0.00067 19.7 0.5 0.032 14.2 0.5 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OWF47297.1 - 0.0036 16.8 0.0 0.0081 15.6 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein OB_Dis3 PF17849.1 OWF47297.1 - 0.0098 15.9 0.0 0.077 13.0 0.0 2.5 1 1 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) AAA_32 PF13654.6 OWF47297.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 OWF47297.1 - 0.045 13.6 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 OWF47297.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ChlI PF13541.6 OWF47297.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase RsgA_GTPase PF03193.16 OWF47297.1 - 0.11 12.3 0.0 9.8 6.1 0.0 2.9 2 0 0 2 2 2 0 RsgA GTPase AAA_11 PF13086.6 OWF47298.1 - 1.6e-14 54.4 1.1 3.4e-14 53.2 1.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF47298.1 - 7e-06 26.4 0.0 2.9e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OWF47298.1 - 0.00019 21.1 2.9 0.00042 19.9 2.3 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 OWF47298.1 - 0.001 18.4 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OWF47298.1 - 0.0012 18.6 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OWF47298.1 - 0.0067 15.9 0.0 0.047 13.1 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 OWF47298.1 - 0.024 14.6 2.1 0.2 11.6 2.2 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF47298.1 - 0.024 14.9 0.1 0.12 12.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OWF47298.1 - 0.027 14.5 0.0 0.079 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OWF47298.1 - 0.03 14.7 0.2 0.53 10.7 0.2 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 OWF47298.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 OWF47298.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 OWF47298.1 - 0.093 13.1 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 OWF47298.1 - 0.11 12.2 0.1 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MFS_1 PF07690.16 OWF47299.1 - 9.9e-56 189.2 28.3 1.1e-52 179.1 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF47299.1 - 3.3e-06 26.2 19.0 3.3e-06 26.2 19.0 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter HEPN_DZIP3 PF18738.1 OWF47300.1 - 1.8e-27 95.9 0.0 4e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN Roc PF08477.13 OWF47300.1 - 2.3e-08 34.3 0.2 4.4e-06 26.9 0.1 2.6 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF47300.1 - 0.024 14.2 2.2 0.041 13.5 0.3 2.3 3 0 0 3 3 3 0 Ras family ComGF PF15980.5 OWF47300.1 - 0.042 14.2 0.3 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Putative Competence protein ComGF VirB3 PF05101.13 OWF47301.1 - 0.011 16.0 0.9 8.5 6.7 0.0 3.5 4 0 0 4 4 4 0 Type IV secretory pathway, VirB3-like protein POT1PC PF16686.5 OWF47301.1 - 1.3 8.9 5.2 19 5.1 1.3 3.2 1 1 1 2 2 2 0 ssDNA-binding domain of telomere protection protein PPR PF01535.20 OWF47301.1 - 3.1 8.3 8.4 3.8 8.0 0.3 3.4 4 1 1 5 5 5 0 PPR repeat OATP PF03137.20 OWF47303.1 - 1.6e-70 238.0 12.9 3.3e-70 236.9 12.9 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF47303.1 - 2.3e-15 56.4 11.3 2.8e-15 56.1 11.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF47303.1 - 3e-07 30.4 2.6 5.8e-07 29.5 2.6 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF47303.1 - 0.002 18.1 3.6 0.0044 17.0 3.6 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain LapA_dom PF06305.11 OWF47303.1 - 0.37 10.6 5.9 0.19 11.6 1.8 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 OWF47304.1 - 3.3e-39 134.8 23.6 4e-19 68.7 10.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF47304.1 - 2.9e-07 29.7 16.7 4.5e-07 29.1 0.7 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 OWF47304.1 - 4.2e-07 28.7 0.3 0.0055 15.0 0.0 3.0 3 0 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family NKAIN PF05640.14 OWF47306.1 - 2.3e-66 223.0 7.0 3e-66 222.6 7.0 1.1 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Asp_Arg_Hydrox PF05118.15 OWF47307.1 - 1.2e-60 203.9 0.1 2.5e-60 202.8 0.1 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.17 OWF47307.1 - 1.1e-08 34.5 0.9 0.1 12.7 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF47307.1 - 3.3e-08 33.7 0.2 0.012 16.3 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF47307.1 - 1.5e-06 28.5 0.0 0.067 14.0 0.0 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF47307.1 - 1.6e-06 27.7 0.1 3.4e-05 23.4 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 OWF47307.1 - 1.3e-05 24.8 0.4 0.15 11.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF47307.1 - 0.00065 20.2 0.0 0.027 15.0 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF47307.1 - 0.0012 18.9 1.0 0.84 10.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF47307.1 - 0.0016 18.7 0.0 1.4 9.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF47307.1 - 0.0017 19.0 0.0 0.04 14.6 0.0 2.8 2 1 2 4 4 4 1 Tetratricopeptide repeat RhoGAP PF00620.27 OWF47308.1 - 6.9e-39 133.1 0.2 1.2e-38 132.3 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain Tyr-DNA_phospho PF06087.12 OWF47308.1 - 0.073 12.0 0.3 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Tyrosyl-DNA phosphodiesterase Glyco_transf_10 PF00852.19 OWF47309.1 - 7e-48 162.7 0.2 1.3e-47 161.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF47309.1 - 2.3e-17 63.4 0.8 6.1e-17 62.1 0.8 1.8 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Arch_fla_DE PF04659.13 OWF47309.1 - 0.16 11.8 0.1 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Archaeal flagella protein Glyco_transf_10 PF00852.19 OWF47310.1 - 8.1e-34 116.9 0.5 1.9e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF47310.1 - 4.2e-17 62.6 0.2 4.2e-17 62.6 0.2 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal RHH_4 PF13467.6 OWF47311.1 - 0.082 12.8 0.1 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain Glyco_transf_10 PF00852.19 OWF47312.1 - 5.6e-41 140.2 0.1 1.1e-40 139.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF47312.1 - 2.3e-17 63.4 0.5 5.3e-17 62.3 0.5 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal NeA_P2 PF12312.8 OWF47312.1 - 0.14 11.6 1.5 9.3 5.6 0.0 3.0 3 0 0 3 3 3 0 Nepovirus subgroup A polyprotein Glyco_transf_10 PF00852.19 OWF47313.1 - 5.5e-48 163.0 0.2 9.8e-48 162.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF47313.1 - 5.3e-17 62.3 0.5 1.4e-16 60.9 0.5 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Tetraspanin PF00335.20 OWF47314.1 - 1.2e-43 149.5 19.3 1.4e-43 149.3 19.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Shisa PF13908.6 OWF47314.1 - 0.013 15.8 2.5 0.013 15.8 2.5 3.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF515 PF04415.12 OWF47314.1 - 0.12 10.7 6.3 1.8 6.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) OATP PF03137.20 OWF47315.1 - 5.5e-178 592.7 16.4 5.5e-178 592.7 16.4 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF47315.1 - 2.5e-23 82.6 15.4 2.5e-23 82.6 15.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF47315.1 - 7.1e-07 29.3 6.5 7.1e-07 29.3 6.5 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF47315.1 - 0.009 16.0 5.8 0.029 14.4 5.8 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DHHC PF01529.20 OWF47316.1 - 2.3e-26 92.5 10.9 2.3e-26 92.5 10.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1894 PF08979.11 OWF47316.1 - 0.97 9.8 4.8 40 4.7 0.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1894) CLIP1_ZNF PF16641.5 OWF47316.1 - 4.4 7.3 8.2 1.7 8.7 0.4 2.3 2 0 0 2 2 2 0 CLIP1 zinc knuckle DHHC PF01529.20 OWF47317.1 - 2.2e-25 89.3 11.8 2.2e-25 89.3 11.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase GCS PF03074.16 OWF47318.1 - 2.9e-177 589.5 0.3 3.6e-177 589.2 0.3 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 OWF47318.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) 7TM_GPCR_Srw PF10324.9 OWF47319.1 - 3.2e-13 49.7 17.4 2.1e-12 47.0 17.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF47319.1 - 4.3e-10 39.4 19.1 4.3e-10 39.4 19.1 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 OWF47320.1 - 4e-09 36.2 19.2 4e-09 36.2 19.2 1.4 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Ig_3 PF13927.6 OWF47321.1 - 3.5e-06 27.5 0.1 3.5e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF47321.1 - 0.00012 22.1 0.0 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Peptidase_S24 PF00717.23 OWF47322.1 - 7.6e-10 38.6 0.1 1.2e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like KaiB PF07689.12 OWF47323.1 - 0.0032 17.2 0.6 0.0071 16.1 0.6 1.5 1 0 0 1 1 1 1 KaiB domain CrgA PF06781.12 OWF47323.1 - 0.011 15.7 2.2 0.032 14.3 2.2 1.8 1 0 0 1 1 1 0 Cell division protein CrgA FtsX PF02687.21 OWF47323.1 - 0.91 10.0 10.5 1.9 9.0 0.6 2.3 1 1 1 2 2 2 0 FtsX-like permease family DUF981 PF06168.11 OWF47323.1 - 4.1 7.3 14.3 1.4 8.9 9.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF981) HIT PF01230.23 OWF47324.1 - 1.6e-29 102.5 0.0 1.9e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OWF47324.1 - 2.8e-25 89.0 0.0 3.4e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.15 OWF47324.1 - 0.00038 20.1 0.2 0.0017 18.1 0.2 1.8 1 1 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase Ras PF00071.22 OWF47325.1 - 1.6e-50 170.8 0.1 1.9e-50 170.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47325.1 - 4.6e-33 114.0 0.1 7.8e-33 113.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF47325.1 - 5.1e-14 52.1 0.0 5.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF47325.1 - 0.0009 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF47325.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF47325.1 - 0.0032 16.8 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 OWF47325.1 - 0.12 11.9 0.6 0.43 10.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Ras PF00071.22 OWF47326.1 - 1.1e-66 223.5 0.6 1.3e-66 223.2 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47326.1 - 2.6e-34 118.0 0.2 4.9e-34 117.1 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF47326.1 - 3.8e-17 62.3 0.3 4.8e-17 62.0 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF47326.1 - 5.7e-06 25.9 0.2 7.3e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OWF47326.1 - 1.4e-05 24.7 0.2 1.8e-05 24.3 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OWF47326.1 - 0.00039 20.0 0.1 0.00067 19.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF47326.1 - 0.0023 18.0 0.1 0.004 17.2 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF47326.1 - 0.014 15.3 0.2 4.9 7.0 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Septin PF00735.18 OWF47326.1 - 0.03 13.6 0.7 0.18 11.0 0.0 2.2 2 1 0 2 2 2 0 Septin AAA_7 PF12775.7 OWF47326.1 - 0.042 13.4 0.2 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OWF47326.1 - 0.17 12.2 0.0 0.42 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 OWF47327.1 - 1.5e-34 119.0 0.0 1.7e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47327.1 - 1.5e-17 63.9 0.0 2.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF47327.1 - 3.9e-08 33.0 0.1 5.5e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF47327.1 - 5e-07 29.5 0.2 3.5e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF47327.1 - 0.0015 18.5 0.1 0.018 14.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OWF47327.1 - 0.0025 17.9 0.2 0.005 16.9 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OWF47327.1 - 0.038 14.0 0.2 0.065 13.3 0.2 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 OWF47327.1 - 0.046 13.5 0.3 0.57 9.9 0.3 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TIR_2 PF13676.6 OWF47328.1 - 4.3e-25 88.6 0.0 1e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 TIR domain Arm PF00514.23 OWF47328.1 - 1.3e-05 25.1 0.0 4.1e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat KAP PF05804.12 OWF47328.1 - 0.0051 15.0 0.3 0.022 13.0 0.1 1.9 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) SAM_3 PF18016.1 OWF47328.1 - 0.0055 16.5 0.1 0.35 10.7 0.0 2.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TIR PF01582.20 OWF47328.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 TIR domain S10_plectin PF03501.15 OWF47328.1 - 0.035 14.2 0.1 0.22 11.6 0.1 2.4 1 0 0 1 1 1 0 Plectin/S10 domain HEAT_EZ PF13513.6 OWF47328.1 - 0.05 14.1 0.0 16 6.1 0.0 2.7 1 1 1 2 2 2 0 HEAT-like repeat Glyoxalase PF00903.25 OWF47328.1 - 0.12 12.5 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TIR_2 PF13676.6 OWF47329.1 - 0.0022 18.6 0.0 0.0062 17.1 0.0 1.8 1 0 0 1 1 1 1 TIR domain ANAPC3 PF12895.7 OWF47329.1 - 0.0033 17.6 5.3 0.015 15.6 0.2 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OWF47329.1 - 0.0039 17.3 0.0 0.025 14.8 0.0 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF47329.1 - 0.0056 16.4 0.2 0.038 13.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF47329.1 - 0.01 15.9 1.9 0.064 13.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF47329.1 - 0.07 13.4 1.6 0.29 11.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OWF47329.1 - 0.073 13.2 0.3 13 5.9 0.0 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Paz_1 PF18349.1 OWF47329.1 - 0.14 12.2 0.1 0.42 10.6 0.1 1.8 1 0 0 1 1 1 0 PAZ domain Neuralized PF07177.12 OWF47330.1 - 1.5e-17 64.0 0.1 5.3e-09 36.3 0.1 2.2 2 0 0 2 2 2 2 Neuralized Kringle PF00051.18 OWF47331.1 - 1e-14 54.6 6.2 2.6e-14 53.3 6.2 1.7 1 0 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.6 OWF47333.1 - 0.0026 18.6 0.9 0.0079 17.1 0.4 2.0 1 1 1 2 2 2 1 Trypsin-like peptidase domain ORC6 PF05460.13 OWF47334.1 - 0.064 12.5 1.5 0.076 12.3 1.5 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ANAPC16 PF17256.2 OWF47334.1 - 0.092 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 RsbRD_N PF14361.6 OWF47335.1 - 0.0095 16.6 3.2 0.18 12.5 0.2 3.3 3 1 0 3 3 3 1 RsbT co-antagonist protein rsbRD N-terminal domain DUF29 PF01724.16 OWF47335.1 - 0.016 15.4 0.6 0.051 13.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF29 Neur_chan_LBD PF02931.23 OWF47336.1 - 5.3e-46 156.8 1.2 7.6e-46 156.3 1.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF47336.1 - 1.1e-17 64.9 0.7 1.1e-17 64.9 0.7 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF47337.1 - 3.1e-41 141.2 5.1 4e-41 140.8 5.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF47337.1 - 5.6e-05 23.3 6.1 0.0001 22.5 6.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4793 PF16041.5 OWF47337.1 - 0.023 14.8 2.7 5.9 7.1 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4793) Neur_chan_LBD PF02931.23 OWF47338.1 - 3.4e-41 141.1 1.1 4.8e-41 140.6 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF47338.1 - 1.9e-11 44.5 11.2 1.9e-11 44.5 11.2 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF47339.1 - 3.9e-46 157.2 3.9 5.1e-46 156.8 3.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF47339.1 - 1.9e-10 41.2 4.2 1.9e-10 41.2 4.2 1.8 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Cation_ATPase_C PF00689.21 OWF47339.1 - 3.5 7.3 9.5 1.2 8.8 5.0 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Neur_chan_LBD PF02931.23 OWF47340.1 - 6.1e-46 156.6 2.1 1e-45 155.9 2.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF47340.1 - 9.5e-12 45.5 11.6 9.5e-12 45.5 11.6 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region F5_F8_type_C PF00754.25 OWF47341.1 - 3.9e-23 81.9 3.6 6.6e-23 81.2 3.6 1.3 1 0 0 1 1 1 1 F5/8 type C domain Lectin_C PF00059.21 OWF47341.1 - 0.00029 21.6 0.0 0.00029 21.6 0.0 2.4 3 1 1 4 4 4 1 Lectin C-type domain Muskelin_N PF06588.11 OWF47341.1 - 0.018 15.0 0.3 0.031 14.2 0.3 1.3 1 0 0 1 1 1 0 Muskelin N-terminus DUF3787 PF12655.7 OWF47341.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) F5_F8_type_C PF00754.25 OWF47342.1 - 7.4e-24 84.3 2.5 1.3e-23 83.5 2.5 1.4 1 0 0 1 1 1 1 F5/8 type C domain Lectin_C PF00059.21 OWF47342.1 - 8.2e-05 23.3 2.5 0.00011 22.9 0.0 2.3 2 1 1 3 3 3 1 Lectin C-type domain Muskelin_N PF06588.11 OWF47342.1 - 0.055 13.4 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Muskelin N-terminus COG5 PF10392.9 OWF47342.1 - 0.11 12.7 2.7 0.83 9.8 0.3 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3787 PF12655.7 OWF47342.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) 7tm_1 PF00001.21 OWF47343.1 - 4.9e-51 173.6 25.2 7.3e-51 173.0 25.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF47343.1 - 1.3e-09 37.8 23.2 1.8e-09 37.4 23.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF47343.1 - 1.7e-06 28.0 17.5 4.2e-05 23.4 17.5 2.4 1 1 0 1 1 1 1 Olfactory receptor Homeodomain PF00046.29 OWF47345.1 - 1.4e-22 79.2 1.7 2.4e-22 78.6 1.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF47345.1 - 0.0086 16.0 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OWF47345.1 - 0.054 13.0 0.1 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 OWF47345.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_28 PF13518.6 OWF47345.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Mtc PF03820.17 OWF47346.1 - 4e-115 384.2 0.3 4.7e-115 383.9 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF2955 PF11168.8 OWF47346.1 - 0.009 15.9 0.3 0.019 14.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2955) HA2 PF04408.23 OWF47347.1 - 5.8e-24 84.5 0.2 1.2e-23 83.4 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OWF47347.1 - 1.3e-20 73.5 0.0 6.1e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OWF47347.1 - 1.6e-12 47.8 0.0 4.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF47347.1 - 3.6e-07 30.1 0.0 6.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OWF47347.1 - 0.00011 22.5 0.1 0.00028 21.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF47347.1 - 0.0008 19.7 0.1 0.0045 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OWF47347.1 - 0.017 14.7 0.1 0.048 13.3 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 OWF47347.1 - 0.019 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_25 PF13481.6 OWF47347.1 - 0.022 14.3 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OWF47347.1 - 0.033 13.7 0.1 0.24 10.9 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region HTH_IclR PF09339.10 OWF47347.1 - 0.052 13.3 0.1 0.21 11.4 0.2 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain ABC_tran PF00005.27 OWF47347.1 - 0.065 13.8 0.0 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 OWF47347.1 - 0.072 13.1 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OWF47347.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OWF47347.1 - 0.15 11.5 0.0 0.43 10.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 OWF47347.1 - 0.15 11.0 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4695 PF15766.5 OWF47348.1 - 0.047 13.9 0.1 0.086 13.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4695) DBB PF14545.6 OWF47349.1 - 0.0025 17.7 34.9 0.16 11.9 3.8 5.1 1 1 4 5 5 5 5 Dof, BCAP, and BANK (DBB) motif, DUF1106 PF06523.11 OWF47349.1 - 0.012 15.6 40.4 12 6.0 2.5 9.7 1 1 9 10 10 10 0 Protein of unknown function (DUF1106) Filamin PF00630.19 OWF47349.1 - 2.4 9.0 47.7 1.1e+02 3.6 1.5 8.8 1 1 2 3 3 3 0 Filamin/ABP280 repeat EMP24_GP25L PF01105.24 OWF47350.1 - 1.6e-44 152.0 0.4 1.8e-44 151.9 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF658 PF04936.12 OWF47350.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) WAP PF00095.21 OWF47351.1 - 1.5e-09 38.1 14.6 1.5e-09 38.1 14.6 7.8 7 0 0 7 7 7 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' zf-CCCH_4 PF18044.1 OWF47352.1 - 2.2e-09 36.9 3.7 3.5e-09 36.3 3.7 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OWF47352.1 - 1.2e-05 25.2 7.0 2e-05 24.5 7.0 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OWF47352.1 - 0.00026 20.8 2.1 0.00047 20.0 2.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OWF47352.1 - 0.0022 18.7 0.1 0.0022 18.7 0.1 3.2 3 0 0 3 3 3 1 Torus domain CTNNBL PF08216.11 OWF47353.1 - 1.2e-37 128.2 3.7 4.1e-37 126.5 3.7 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear PDCD2_C PF04194.13 OWF47353.1 - 0.26 11.3 6.0 0.16 12.1 1.5 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain UCR_TM PF02921.14 OWF47354.1 - 2.4e-17 63.1 0.2 5.8e-17 61.9 0.2 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 OWF47354.1 - 1.4e-11 44.2 0.0 2.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_Fe-S_N PF10399.9 OWF47354.1 - 0.16 11.3 0.1 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Chromo PF00385.24 OWF47355.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Corona_nucleoca PF00937.18 OWF47355.1 - 0.025 13.6 11.2 0.033 13.2 11.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Tudor-knot PF11717.8 OWF47355.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Transformer PF06495.11 OWF47355.1 - 0.16 12.1 13.0 0.27 11.3 13.0 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein DUF4228 PF14009.6 OWF47355.1 - 0.97 9.8 8.0 1.6 9.1 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Peptidase_S64 PF08192.11 OWF47355.1 - 1 7.8 5.1 1.3 7.5 5.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1509 PF07420.11 OWF47355.1 - 7.1 5.5 12.5 10 4.9 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MDFI PF15316.6 OWF47355.1 - 10 6.2 9.4 22 5.1 0.4 2.2 1 1 1 2 2 2 0 MyoD family inhibitor eIF-5_eIF-2B PF01873.17 OWF47356.1 - 3.3e-40 136.6 0.1 5.8e-40 135.8 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TNFR_c6 PF00020.18 OWF47357.1 - 1.9e-20 73.0 40.8 4.3e-07 30.2 1.5 4.3 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region TRP PF06011.12 OWF47357.1 - 0.034 12.9 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Mpv17_PMP22 PF04117.12 OWF47358.1 - 0.0079 16.4 1.0 0.022 15.0 1.0 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family UCH PF00443.29 OWF47359.1 - 1.6e-55 188.4 0.9 2.6e-55 187.7 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OWF47359.1 - 4.7e-17 62.1 12.7 4.7e-17 62.1 12.7 3.3 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OWF47359.1 - 8.9e-15 55.1 9.3 1.3e-14 54.6 3.6 3.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase PH_12 PF16457.5 OWF47360.1 - 5e-14 53.0 0.0 9.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_14 PF17787.1 OWF47360.1 - 9.3e-05 22.3 0.1 0.00023 21.0 0.1 1.6 1 1 0 1 1 1 1 PH domain PI-PLC-X PF00388.19 OWF47361.1 - 2.1e-61 205.8 0.0 4.6e-61 204.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OWF47361.1 - 3.1e-43 146.7 0.6 6.3e-43 145.8 0.6 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 OWF47361.1 - 2.4e-17 63.2 0.0 7.4e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 OWF47361.1 - 6.4e-13 48.9 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain PI-PLC-X PF00388.19 OWF47362.1 - 4.7e-56 188.4 0.1 9e-56 187.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OWF47362.1 - 1.5e-40 138.1 0.3 5.2e-40 136.4 0.3 2.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 OWF47362.1 - 1.4e-12 47.9 0.0 3.8e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 OWF47362.1 - 5.9e-05 23.3 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 OWF47362.1 - 0.022 15.3 3.2 0.11 13.1 0.1 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain PglZ PF08665.12 OWF47362.1 - 0.061 13.4 2.0 0.11 12.6 0.2 2.2 2 0 0 2 2 2 0 PglZ domain PH PF00169.29 OWF47362.1 - 0.082 13.4 1.7 0.23 12.0 0.1 2.8 2 0 0 2 2 2 0 PH domain Pkinase PF00069.25 OWF47363.1 - 2.6e-63 213.8 0.0 4.7e-63 213.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF47363.1 - 3.8e-42 144.4 0.0 6.6e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OWF47363.1 - 9e-26 90.3 0.9 2.5e-08 34.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF47363.1 - 4.2e-23 81.1 1.7 6.5e-07 29.5 0.0 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF47363.1 - 1.9e-22 79.3 1.1 0.00037 21.0 0.0 5.9 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF47363.1 - 2.5e-21 75.1 5.3 0.00069 20.0 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OWF47363.1 - 1.6e-12 46.4 0.1 0.0097 16.4 0.0 6.8 6 1 0 6 6 6 2 Ankyrin repeat Kinase-like PF14531.6 OWF47363.1 - 7e-06 25.6 0.0 0.00039 19.8 0.0 2.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OWF47363.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3782 PF12644.7 OWF47363.1 - 0.097 12.8 0.0 0.46 10.7 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) HEAT_2 PF13646.6 OWF47364.1 - 4.1e-19 68.7 14.5 6.5e-08 32.9 2.5 3.9 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 OWF47364.1 - 2e-16 58.7 5.3 0.03 14.6 0.1 7.3 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 OWF47364.1 - 4.1e-13 49.7 9.6 7.8e-05 22.8 0.2 4.2 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OWF47364.1 - 4.4e-12 45.6 0.1 0.0048 16.9 0.1 4.6 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OWF47364.1 - 7.3e-10 38.0 6.0 1.3e-07 30.6 1.3 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OWF47364.1 - 7e-06 26.6 0.6 0.096 13.3 0.0 3.4 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OWF47364.1 - 4.7e-05 23.8 10.7 0.16 12.5 0.1 5.5 3 3 3 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 OWF47364.1 - 7.9e-05 22.8 1.5 0.12 12.5 0.1 3.1 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OWF47364.1 - 0.00039 20.1 1.8 1.4 8.5 0.1 3.9 3 2 0 3 3 3 2 CLASP N terminal DUF3636 PF12331.8 OWF47364.1 - 0.0049 16.7 0.2 1 9.2 0.0 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF3636) Arm_2 PF04826.13 OWF47364.1 - 0.0056 16.2 0.1 0.051 13.0 0.0 2.1 1 1 0 2 2 2 1 Armadillo-like MMS19_N PF14500.6 OWF47364.1 - 0.0066 16.1 3.3 0.78 9.3 0.2 3.6 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II WAPL PF07814.13 OWF47364.1 - 0.015 14.1 0.8 3 6.5 0.2 2.2 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin V-ATPase_H_C PF11698.8 OWF47364.1 - 0.053 13.6 3.2 0.44 10.7 0.3 3.1 2 1 1 3 3 3 0 V-ATPase subunit H Proteasom_PSMB PF10508.9 OWF47364.1 - 0.058 11.9 2.2 2.1 6.7 0.1 2.9 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit RasGEF_N_2 PF14663.6 OWF47364.1 - 0.14 12.5 5.4 13 6.2 0.1 4.2 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Phosphorylase PF00343.20 OWF47364.1 - 0.15 10.3 0.1 0.24 9.7 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate phosphorylase HEAT_PBS PF03130.16 OWF47364.1 - 0.19 12.5 3.9 3.5 8.6 0.0 4.7 6 2 0 6 6 5 0 PBS lyase HEAT-like repeat RRM_DME PF15628.6 OWF47366.1 - 1.2e-05 25.4 2.6 1.6 9.0 0.2 3.8 1 1 2 3 3 3 2 RRM in Demeter Ribosomal_L14e PF01929.17 OWF47366.1 - 0.06 13.8 0.0 34 5.0 0.0 3.2 1 1 3 4 4 4 0 Ribosomal protein L14 Pex14_N PF04695.13 OWF47366.1 - 0.17 12.5 0.2 18 6.0 0.2 4.2 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1497 PF07384.11 OWF47366.1 - 3.6 8.1 35.8 80 3.8 0.4 11.4 1 1 6 7 7 7 0 Protein of unknown function (DUF1497) zn-ribbon_14 PF16503.5 OWF47366.1 - 4.4 6.9 64.2 4.3 6.9 1.5 12.3 2 2 13 15 15 15 0 Zinc-ribbon DUF4573 PF15140.6 OWF47367.1 - 1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Lambda_Kil PF06301.11 OWF47367.1 - 0.0044 16.6 6.0 36 4.1 0.2 5.8 3 2 2 5 5 5 2 Bacteriophage lambda Kil protein PTS_EIIA_2 PF00359.22 OWF47368.1 - 3e-07 30.4 0.1 4.2 7.3 0.0 6.3 3 2 2 6 6 6 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 RMF PF04957.12 OWF47368.1 - 2.4e-05 24.4 6.8 2.6 8.3 0.0 6.8 5 1 3 8 8 8 1 Ribosome modulation factor P63C PF10546.9 OWF47368.1 - 0.00064 20.3 0.1 28 5.4 0.0 4.5 2 1 2 5 5 5 0 P63C domain N-Term_TEN PF11474.8 OWF47368.1 - 0.0031 17.1 3.3 33 4.0 0.0 5.5 2 2 4 7 7 7 0 Telomerase reverse transcriptase TEN domain CHDNT PF08073.12 OWF47368.1 - 0.0057 16.6 0.5 8.5 6.4 0.0 3.3 3 0 0 3 3 3 2 CHDNT (NUC034) domain Trns_repr_metal PF02583.17 OWF47368.1 - 0.016 15.6 13.3 4.5 7.7 0.1 5.8 4 4 1 5 5 5 0 Metal-sensitive transcriptional repressor HTH_47 PF16221.5 OWF47368.1 - 0.13 11.8 0.0 22 4.7 0.0 3.8 4 1 2 6 6 6 0 winged helix-turn-helix DUF3731 PF12531.8 OWF47368.1 - 0.14 11.9 4.8 2.1 8.1 0.1 3.9 1 1 1 3 3 3 0 DNA-K related protein FYRC PF05965.14 OWF47368.1 - 0.18 12.0 11.3 19 5.5 0.3 5.9 1 1 6 8 8 8 0 F/Y rich C-terminus HWE_HK PF07536.14 OWF47368.1 - 0.46 11.2 10.4 6.9 7.4 0.0 4.6 5 1 1 6 6 5 0 HWE histidine kinase Amelotin PF15757.5 OWF47368.1 - 0.89 9.1 16.9 0.83 9.2 0.3 4.2 2 1 2 4 4 4 0 Amelotin RHH_3 PF12651.7 OWF47369.1 - 0.00086 19.2 1.5 89 3.2 0.0 6.9 8 1 2 10 10 10 0 Ribbon-helix-helix domain Kin17_mid PF10357.9 OWF47369.1 - 0.0014 18.5 6.0 1.6 8.7 0.1 5.4 1 1 5 6 6 6 1 Domain of Kin17 curved DNA-binding protein FcoT PF10862.8 OWF47369.1 - 0.015 14.9 13.0 1.2 8.7 0.2 5.0 1 1 3 5 5 5 0 FcoT-like thioesterase domain DUF1202 PF06717.11 OWF47369.1 - 0.19 11.1 0.0 7.7 5.8 0.0 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1202) Cucumo_coat PF00760.18 OWF47369.1 - 2.2 7.9 7.1 6.2 6.5 1.2 2.5 2 1 1 3 3 3 0 Cucumovirus coat protein Kin17_mid PF10357.9 OWF47370.1 - 0.0071 16.3 10.3 7.7 6.4 0.0 6.2 5 4 2 8 8 8 4 Domain of Kin17 curved DNA-binding protein CBM39 PF15886.5 OWF47371.1 - 0.087 12.7 3.7 0.2 11.6 0.5 2.6 2 1 1 3 3 3 0 Carbohydrate binding domain (family 32) FNIP PF05725.12 OWF47371.1 - 0.24 11.6 2.9 13 6.0 0.0 4.2 6 1 1 7 7 7 0 FNIP Repeat Galactosyl_T PF01762.21 OWF47372.1 - 4.3e-46 157.2 0.2 7.6e-46 156.4 0.2 1.4 1 0 0 1 1 1 1 Galactosyltransferase Phage_HK97_TLTM PF06120.11 OWF47372.1 - 0.06 12.5 1.4 0.11 11.7 1.4 1.4 1 0 0 1 1 1 0 Tail length tape measure protein C1q PF00386.21 OWF47373.1 - 4e-16 59.4 0.0 6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 OWF47374.1 - 3e-19 69.5 0.2 7.7e-19 68.2 0.2 1.7 1 0 0 1 1 1 1 C1q domain Synaptobrevin PF00957.21 OWF47374.1 - 0.19 11.6 6.3 0.11 12.2 3.4 2.1 2 0 0 2 2 2 0 Synaptobrevin C1q PF00386.21 OWF47375.1 - 1.7e-19 70.3 0.2 3.1e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 C1q domain TMF_DNA_bd PF12329.8 OWF47376.1 - 0.014 15.3 1.8 0.021 14.8 1.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding USP8_interact PF08941.10 OWF47376.1 - 0.015 15.1 0.6 0.022 14.6 0.6 1.2 1 0 0 1 1 1 0 USP8 interacting FliJ PF02050.16 OWF47376.1 - 0.035 14.3 6.2 0.049 13.9 6.2 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein IFT57 PF10498.9 OWF47376.1 - 0.087 11.8 2.9 0.12 11.4 2.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3450 PF11932.8 OWF47376.1 - 0.15 11.3 3.8 0.21 10.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 OWF47376.1 - 0.18 12.1 1.2 0.27 11.5 1.2 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Gp58 PF07902.11 OWF47376.1 - 0.18 10.0 5.9 0.25 9.6 5.9 1.1 1 0 0 1 1 1 0 gp58-like protein DUF16 PF01519.16 OWF47376.1 - 0.21 12.1 3.2 0.34 11.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 OWF47376.1 - 1.8 8.8 7.1 3.3 7.9 4.8 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OWF47376.1 - 6.2 7.5 10.0 11 6.7 3.1 2.2 1 1 1 2 2 2 0 SlyX zf-3CxxC_2 PF17180.4 OWF47377.1 - 0.00018 22.2 17.4 0.00065 20.4 17.4 2.0 1 1 0 1 1 1 1 Zinc-binding domain zf-3CxxC PF13695.6 OWF47377.1 - 0.00033 21.1 12.8 0.00058 20.3 12.8 1.5 1 1 0 1 1 1 1 Zinc-binding domain DZR PF12773.7 OWF47377.1 - 1.7 8.7 16.7 7.8 6.6 11.4 2.2 1 1 2 3 3 3 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 OWF47377.1 - 1.9 8.6 11.0 1.9 8.6 6.3 2.9 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Sgf11 PF08209.11 OWF47377.1 - 2.3 7.9 11.1 2.5 7.7 0.5 3.3 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-3CxxC PF13695.6 OWF47378.1 - 3.4e-07 30.7 22.8 3.5e-06 27.4 22.8 2.1 1 1 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 OWF47378.1 - 3.1e-06 27.8 25.6 0.0052 17.5 25.6 2.8 1 1 0 1 1 1 1 Zinc-binding domain DUF1232 PF06803.12 OWF47379.1 - 3.9e-11 42.6 10.1 3.9e-11 42.6 10.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-C3HC4 PF00097.25 OWF47379.1 - 1.3e-08 34.6 2.9 2e-08 33.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF47379.1 - 2.5e-08 33.8 2.4 7.3e-08 32.3 1.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF47379.1 - 3.8e-08 33.0 4.0 7.9e-08 32.0 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF47379.1 - 7.1e-08 32.5 6.0 1.2e-07 31.8 6.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF47379.1 - 1.1e-07 32.0 4.8 1.7e-07 31.4 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF47379.1 - 1.5e-07 31.1 2.4 2.3e-07 30.6 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF47379.1 - 9e-06 25.6 4.2 2.5e-05 24.1 4.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF47379.1 - 5e-05 23.1 3.4 0.0037 17.1 1.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OWF47379.1 - 0.0016 18.2 0.1 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF1644 PF07800.12 OWF47379.1 - 0.0072 16.4 0.2 2.1 8.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1644) zf-Di19 PF05605.12 OWF47379.1 - 0.0076 16.5 2.8 2.9 8.2 0.4 2.4 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF5318 PF17249.2 OWF47379.1 - 0.0081 15.9 0.1 4.6 7.0 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5318) zf-ANAPC11 PF12861.7 OWF47379.1 - 0.11 12.6 2.9 0.21 11.6 2.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OWF47379.1 - 0.74 9.7 4.3 2.2 8.2 4.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OWF47379.1 - 0.77 9.6 6.2 0.23 11.2 2.7 2.0 2 1 0 2 2 2 0 RING-like zinc finger zinc-ribbons_6 PF07191.12 OWF47379.1 - 0.79 9.7 6.5 1 9.4 2.0 2.1 1 1 1 2 2 2 0 zinc-ribbons YacG PF03884.14 OWF47379.1 - 1.2 8.9 3.7 12 5.7 0.1 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-MIZ PF02891.20 OWF47379.1 - 1.2 8.9 4.2 2.2 8.1 4.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 OWF47379.1 - 3.1 8.1 8.5 17 5.8 8.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain TF_Zn_Ribbon PF08271.12 OWF47379.1 - 4.5 6.9 9.3 1.7 8.3 5.6 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Tctex-1 PF03645.13 OWF47380.1 - 1.6e-16 60.4 0.3 2.5e-16 59.8 0.3 1.3 1 0 0 1 1 1 1 Tctex-1 family CFTR_R PF14396.6 OWF47380.1 - 0.6 9.6 11.8 2.1 7.9 7.2 2.6 1 1 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain RHH_7 PF16777.5 OWF47380.1 - 1.1 9.7 5.1 2.8 8.4 0.0 2.6 2 1 1 3 3 3 0 Transcriptional regulator, RHH-like, CopG Tctex-1 PF03645.13 OWF47381.1 - 6e-18 65.0 0.1 8.7e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family gp32 PF08804.10 OWF47381.1 - 0.02 15.0 0.1 0.027 14.5 0.1 1.1 1 0 0 1 1 1 0 gp32 DNA binding protein like PAP_assoc PF03828.19 OWF47382.1 - 8.6e-24 83.5 0.4 2.3e-10 40.5 0.1 3.1 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OWF47382.1 - 6.9e-13 48.7 4.6 2.6e-07 30.8 0.0 4.4 3 1 1 4 4 4 2 Nucleotidyltransferase domain zf-CCHC PF00098.23 OWF47382.1 - 9.8e-06 25.4 10.2 0.0067 16.4 4.1 2.9 2 0 0 2 2 2 2 Zinc knuckle Polbeta PF18765.1 OWF47382.1 - 9.6e-05 22.4 2.0 0.12 12.5 0.0 3.7 3 1 0 3 3 3 2 Polymerase beta, Nucleotidyltransferase zf-C2H2_2 PF12756.7 OWF47382.1 - 0.036 14.4 2.4 0.14 12.5 0.5 3.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) EloA-BP1 PF15870.5 OWF47383.1 - 1.9e-61 207.1 0.0 1.9e-61 207.1 0.0 6.5 3 2 1 4 4 4 1 ElonginA binding-protein 1 Bacteriocin_II PF01721.18 OWF47383.1 - 0.011 15.9 0.2 0.033 14.3 0.2 1.8 1 0 0 1 1 1 0 Class II bacteriocin ShK PF01549.24 OWF47384.1 - 0.00052 20.5 6.9 0.00087 19.8 6.9 1.3 1 0 0 1 1 1 1 ShK domain-like MFS_5 PF05631.14 OWF47387.1 - 0.0019 17.2 4.0 0.14 11.0 0.2 2.5 1 1 2 3 3 3 3 Sugar-tranasporters, 12 TM CysA_C_terminal PF17850.1 OWF47387.1 - 0.043 14.4 3.8 1.6e+02 2.9 0.0 5.0 5 0 0 5 5 5 0 CysA C-terminal regulatory domain HSD3 PF15244.6 OWF47387.1 - 0.3 10.5 10.2 0.28 10.6 0.5 2.8 1 1 2 3 3 3 0 Spermatogenesis-associated protein 7, or HSD3 DUF4149 PF13664.6 OWF47387.1 - 0.56 10.6 3.2 1.4e+02 2.9 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4149) HYLS1_C PF15311.6 OWF47387.1 - 0.7 10.7 8.5 52 4.7 0.2 4.2 1 1 5 6 6 6 0 Hydrolethalus syndrome protein 1 C-terminus Borrelia_orfA PF02414.15 OWF47387.1 - 7.8 6.1 10.1 7.6 6.1 2.0 2.8 1 1 1 2 2 2 0 Borrelia ORF-A Bee_toxin PF17454.2 OWF47388.1 - 0.0002 21.3 13.7 8.4 6.5 0.1 6.7 3 1 5 8 8 8 4 Honey bee toxin CysA_C_terminal PF17850.1 OWF47388.1 - 0.00069 20.1 6.6 2.1e+02 2.6 0.0 7.6 9 0 0 9 9 9 0 CysA C-terminal regulatory domain HYLS1_C PF15311.6 OWF47388.1 - 1 10.2 9.1 47 4.8 0.1 4.4 1 1 2 5 5 5 0 Hydrolethalus syndrome protein 1 C-terminus ASFV_p27 PF06556.11 OWF47388.1 - 1.6 8.8 11.6 0.054 13.6 2.7 2.3 1 1 1 2 2 2 0 IAP-like protein p27 C-terminus MFS_5 PF05631.14 OWF47389.1 - 0.096 11.6 8.6 0.46 9.3 0.9 3.0 1 1 3 4 4 4 0 Sugar-tranasporters, 12 TM MFA1_2 PF17317.2 OWF47389.1 - 0.2 11.5 0.7 66 3.4 0.0 3.5 4 0 0 4 4 4 0 Mating hormone A-factor 1&2 EF-hand_1 PF00036.32 OWF47391.1 - 0.00022 20.5 0.9 0.00045 19.6 0.9 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OWF47391.1 - 0.00027 20.3 0.2 0.00056 19.3 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OWF47391.1 - 0.00029 20.5 0.1 0.00076 19.2 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OWF47391.1 - 0.034 14.6 0.1 0.076 13.5 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 OWF47391.1 - 0.037 13.9 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair PPC PF04151.15 OWF47391.1 - 0.1 13.7 0.1 0.27 12.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain ArfGap PF01412.18 OWF47392.1 - 2.1e-42 143.9 0.6 4.4e-42 142.9 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf LRR_4 PF12799.7 OWF47393.1 - 0.008 16.6 16.5 1.2 9.7 0.0 6.0 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF47393.1 - 0.023 14.7 6.8 30 5.0 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich repeat SPATA1_C PF15743.5 OWF47394.1 - 1.2e-22 80.6 12.2 1.2e-22 80.6 12.2 3.1 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus Hist_deacetyl PF00850.19 OWF47395.1 - 8.4e-79 265.2 0.4 8.4e-79 265.2 0.4 1.3 2 0 0 2 2 2 1 Histone deacetylase domain Sod_Cu PF00080.20 OWF47396.1 - 8.6e-32 110.3 0.3 1.3e-31 109.7 0.3 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2783 PF10932.8 OWF47396.1 - 0.23 11.2 0.2 0.4 10.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) DUF5527 PF17665.1 OWF47397.1 - 0.0018 17.9 11.8 0.76 9.3 1.2 3.7 1 1 3 4 4 4 4 Family of unknown function (DUF5527) Phi29_Phage_SSB PF17427.2 OWF47397.1 - 0.021 15.0 4.6 19 5.5 0.1 3.3 1 1 3 4 4 4 0 Phage Single-stranded DNA-binding protein DUF2259 PF10016.9 OWF47397.1 - 0.025 14.5 1.9 2.8 7.8 1.9 2.9 1 1 0 1 1 1 0 Predicted secreted protein (DUF2259) DnaI_N PF07319.11 OWF47397.1 - 0.21 12.3 2.9 12 6.6 0.1 2.6 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus Coronavirus_5 PF05528.11 OWF47397.1 - 0.3 11.1 11.5 30 4.7 0.1 4.3 1 1 4 6 6 6 0 Coronavirus gene 5 protein GDC-P PF02347.16 OWF47398.1 - 1.5e-189 630.3 0.0 9.4e-181 601.3 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 OWF47398.1 - 8.4e-06 25.0 0.2 0.0012 17.9 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 OWF47398.1 - 1.2e-05 24.7 0.1 2.4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase NPF PF16601.5 OWF47399.1 - 3.1 8.2 5.7 30 5.0 5.1 2.1 1 1 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif Cucumo_2B PF03263.13 OWF47400.1 - 0.15 12.6 0.0 31 5.1 0.0 2.9 1 1 2 3 3 3 0 Cucumovirus protein 2B SnAC PF14619.6 OWF47400.1 - 0.7 10.5 4.3 20 5.9 1.5 3.1 1 1 1 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex PAP2 PF01569.21 OWF47401.1 - 2.3e-14 53.3 2.9 2.3e-14 53.3 2.9 1.7 2 0 0 2 2 2 1 PAP2 superfamily Romo1 PF10247.9 OWF47401.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 AbrB PF05145.12 OWF47401.1 - 0.015 14.3 0.9 0.015 14.3 0.9 2.7 3 0 0 3 3 3 0 Transition state regulatory protein AbrB PhyH PF05721.13 OWF47403.1 - 3.4e-30 105.9 0.0 5.1e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Lipase PF00151.19 OWF47404.1 - 1.3e-104 350.1 0.0 1.7e-104 349.8 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 OWF47404.1 - 1.4e-07 32.3 2.5 2.3e-07 31.6 2.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLAT PF01477.23 OWF47404.1 - 2.1e-05 25.1 0.1 3.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Hydrolase_4 PF12146.8 OWF47404.1 - 0.025 13.8 0.8 0.052 12.8 0.8 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OWF47404.1 - 0.14 11.8 0.9 0.33 10.5 0.9 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold TPR_8 PF13181.6 OWF47405.1 - 1.8e-16 58.9 13.1 0.0014 18.7 0.0 9.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF47405.1 - 3.2e-15 56.4 14.9 0.0028 18.1 0.4 7.3 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 OWF47405.1 - 1e-13 50.5 13.5 0.00065 19.4 0.1 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF47405.1 - 2.6e-13 49.5 5.4 0.00014 22.4 0.1 7.4 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF47405.1 - 1.3e-11 43.7 14.0 0.041 14.0 0.1 8.7 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF47405.1 - 2.1e-11 43.0 1.4 0.2 11.8 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF47405.1 - 5.4e-10 39.3 7.9 0.017 15.7 0.0 7.0 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF47405.1 - 7e-10 39.1 8.0 2.1e-05 24.7 1.0 5.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OWF47405.1 - 5.4e-09 36.1 1.1 0.012 15.7 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF47405.1 - 3.4e-08 33.6 8.2 1.7e-07 31.3 2.0 4.1 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OWF47405.1 - 3.5e-08 34.0 5.3 0.00076 20.1 0.5 5.2 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 OWF47405.1 - 3.6e-08 33.0 6.6 0.0092 15.6 0.1 4.9 4 1 1 5 5 5 2 TPR repeat TPR_15 PF13429.6 OWF47405.1 - 5.7e-07 29.0 5.0 0.00084 18.6 0.8 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF47405.1 - 1.9e-05 24.7 5.2 4.6 7.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Maf_N PF08383.11 OWF47405.1 - 0.0022 17.7 0.3 0.005 16.6 0.3 1.7 1 0 0 1 1 1 1 Maf N-terminal region TPR_20 PF14561.6 OWF47405.1 - 0.0028 18.0 5.5 5.3 7.5 0.0 4.9 2 2 4 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 OWF47405.1 - 0.024 13.7 2.8 0.071 12.1 0.1 2.8 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 OWF47405.1 - 0.028 13.9 2.8 0.42 10.0 0.2 2.7 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPPII_N PF12583.8 OWF47405.1 - 0.032 14.8 1.8 13 6.3 0.0 3.0 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal ANAPC5 PF12862.7 OWF47405.1 - 0.15 12.2 2.9 12 6.0 1.1 3.3 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 5 Alkyl_sulf_dimr PF14863.6 OWF47405.1 - 0.17 12.3 2.9 36 4.8 0.3 3.7 3 1 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 OWF47405.1 - 0.42 10.3 8.9 2 8.1 0.3 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 OWF47405.1 - 1.2 9.1 11.5 9.8 6.2 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 OWF47405.1 - 2.5 9.0 7.4 1.9 9.4 0.3 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.8 OWF47405.1 - 2.8 8.1 13.8 67 3.6 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 ISK_Channel PF02060.15 OWF47406.1 - 6.5e-05 22.6 0.1 8.8e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DUF2678 PF10856.8 OWF47406.1 - 0.0075 16.2 0.0 0.021 14.7 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2678) COX14 PF14880.6 OWF47406.1 - 0.038 13.8 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF5321 PF17254.2 OWF47406.1 - 0.099 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5321) DEK_C PF08766.11 OWF47407.1 - 2.2e-13 49.9 0.6 5.5e-13 48.6 0.6 1.8 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 OWF47407.1 - 0.00044 19.9 0.1 0.0017 18.0 0.1 2.1 1 0 0 1 1 1 1 SAP domain Apt1 PF10351.9 OWF47407.1 - 7.8 5.2 39.8 1.3 7.8 21.0 2.9 3 0 0 3 3 3 0 Golgi-body localisation protein domain IBR PF01485.21 OWF47408.1 - 4.3e-15 55.7 29.7 5.3e-12 45.8 9.5 5.1 3 2 2 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OWF47408.1 - 0.036 14.4 9.0 0.036 14.4 9.0 4.7 4 0 0 4 4 4 0 Ring finger domain Ribonuc_red_sm PF00268.21 OWF47409.1 - 4.7e-123 410.1 3.8 6.1e-123 409.7 3.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SHIPPO-rpt PF07004.12 OWF47410.1 - 0.055 14.4 0.0 0.055 14.4 0.0 5.3 5 1 0 5 5 5 0 Sperm-tail PG-rich repeat Neurensin PF14927.6 OWF47411.1 - 1e-29 102.9 0.0 1.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Neurensin TMEM100 PF16311.5 OWF47411.1 - 0.049 13.2 0.5 0.049 13.2 0.5 2.1 1 1 1 2 2 2 0 Transmembrane protein 100 DUF1427 PF07235.11 OWF47411.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) Ank_3 PF13606.6 OWF47412.1 - 1 10.2 8.9 1.1e+02 3.8 0.0 7.2 6 3 3 9 9 9 0 Ankyrin repeat LRR_1 PF00560.33 OWF47413.1 - 7.1e-05 22.8 0.3 20 6.3 0.3 6.7 1 1 0 1 1 1 1 Leucine Rich Repeat Ank_3 PF13606.6 OWF47413.1 - 0.057 14.0 0.4 1.4e+02 3.6 0.0 4.1 2 2 0 3 3 3 0 Ankyrin repeat DnaB_2 PF07261.11 OWF47413.1 - 2.2 8.1 5.9 28 4.5 0.3 3.7 2 2 1 3 3 3 0 Replication initiation and membrane attachment DUF1106 PF06523.11 OWF47413.1 - 8.9 6.4 5.7 44 4.2 0.7 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1106) PhyH PF05721.13 OWF47415.1 - 1.4e-28 100.6 0.0 2.7e-28 99.7 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MmgE_PrpD PF03972.14 OWF47416.1 - 1.9e-101 339.7 0.0 2.3e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family AIG1 PF04548.16 OWF47417.1 - 1.3e-66 223.9 0.1 4.6e-66 222.2 0.1 1.9 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF47417.1 - 4e-08 33.3 0.0 4e-08 33.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF47417.1 - 9.8e-06 25.2 1.1 1.9e-05 24.2 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 OWF47417.1 - 0.0089 16.5 0.1 0.0089 16.5 0.1 2.7 2 2 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 OWF47417.1 - 0.039 13.9 0.1 0.039 13.9 0.1 2.9 2 1 1 3 3 3 0 RsgA GTPase Toprim PF01751.22 OWF47417.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.2 2 2 0 2 2 2 0 Toprim domain Dynamin_N PF00350.23 OWF47417.1 - 0.2 11.7 0.2 0.2 11.7 0.2 4.5 2 2 1 3 3 3 0 Dynamin family AAA_7 PF12775.7 OWF47417.1 - 0.37 10.3 0.0 0.37 10.3 0.0 3.0 3 1 1 4 4 4 0 P-loop containing dynein motor region ALMT PF11744.8 OWF47417.1 - 5.3 5.8 12.2 6.8 5.4 12.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter AIG1 PF04548.16 OWF47418.1 - 7.4e-59 198.6 0.1 1.1e-58 198.1 0.1 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF47418.1 - 6.3e-06 26.3 0.1 1.6e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OWF47418.1 - 0.0037 17.8 0.1 0.0076 16.8 0.1 1.8 1 1 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 OWF47418.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF87 PF01935.17 OWF47418.1 - 0.015 15.4 0.8 0.073 13.1 0.8 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain Toprim PF01751.22 OWF47418.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Toprim domain GTP-bdg_M PF16360.5 OWF47418.1 - 0.15 12.7 2.7 0.4 11.3 2.2 1.9 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Dynamin_N PF00350.23 OWF47418.1 - 1.7 8.7 6.6 18 5.3 0.1 3.1 2 1 1 3 3 3 0 Dynamin family I-set PF07679.16 OWF47419.1 - 2.7e-06 27.4 0.0 7.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Receptor_2B4 PF11465.8 OWF47419.1 - 0.00045 20.4 0.2 0.0031 17.7 0.1 2.5 2 1 0 2 2 2 1 Natural killer cell receptor 2B4 Ig_3 PF13927.6 OWF47419.1 - 0.00067 20.2 1.1 0.0028 18.2 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain PTEN_C2 PF10409.9 OWF47420.1 - 1.1e-17 64.1 0.1 2e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OWF47420.1 - 2.7e-06 27.2 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ion_trans PF00520.31 OWF47420.1 - 9.3e-05 21.8 8.4 0.00014 21.2 8.4 1.2 1 0 0 1 1 1 1 Ion transport protein Y_phosphatase PF00102.27 OWF47420.1 - 0.00033 20.3 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF47420.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF47420.1 - 0.042 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.9 OWF47421.1 - 5.4e-18 65.0 0.3 5.4e-18 65.0 0.3 1.9 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein Ion_trans PF00520.31 OWF47421.1 - 1e-06 28.2 11.2 1.2e-06 28.0 10.7 1.4 1 1 0 1 1 1 1 Ion transport protein DSPc PF00782.20 OWF47421.1 - 6.7e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF47421.1 - 0.0016 18.6 0.5 0.0029 17.7 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OWF47421.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF47421.1 - 0.046 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EGF PF00008.27 OWF47422.1 - 1.1e-20 73.6 40.2 2.4e-09 37.3 8.4 4.1 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.7 OWF47422.1 - 3.6e-11 43.3 31.8 9.5e-05 22.9 5.6 4.7 3 1 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 OWF47422.1 - 1.9e-08 34.5 44.5 0.0027 18.1 12.7 3.8 3 0 0 3 3 3 3 EGF-like domain EGF_CA PF07645.15 OWF47422.1 - 3.8e-08 33.4 37.6 0.0054 16.9 5.0 3.9 2 1 1 3 3 3 3 Calcium-binding EGF domain EGF_3 PF12947.7 OWF47422.1 - 0.00044 20.4 40.4 0.25 11.6 7.8 4.1 3 0 0 3 3 3 3 EGF domain Plasmod_Pvs28 PF06247.11 OWF47422.1 - 0.0025 18.1 5.3 0.0025 18.1 5.3 4.3 4 0 0 4 4 4 2 Pvs28 EGF domain cEGF PF12662.7 OWF47422.1 - 3.9 7.5 27.7 0.64 10.0 3.1 4.5 3 1 0 3 3 3 0 Complement Clr-like EGF-like EGF PF00008.27 OWF47423.1 - 1.2e-12 47.9 37.2 6.5e-05 23.2 7.5 3.7 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 OWF47423.1 - 2.6e-07 31.0 37.0 0.0015 19.0 5.6 4.7 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 OWF47423.1 - 0.0026 18.1 44.6 0.43 11.0 8.0 3.6 3 0 0 3 3 3 3 EGF-like domain CKAP2_C PF15297.6 OWF47424.1 - 4.8e-23 81.8 10.0 1.7e-17 63.6 0.9 4.2 2 1 1 4 4 4 2 Cytoskeleton-associated protein 2 C-terminus TPR_15 PF13429.6 OWF47424.1 - 0.16 11.1 0.1 0.28 10.3 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat IMD PF08397.11 OWF47425.1 - 2.4e-80 269.1 0.5 3.5e-80 268.5 0.5 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain RRF PF01765.19 OWF47425.1 - 0.98 9.4 8.8 3.8 7.4 8.7 2.0 1 1 0 1 1 1 0 Ribosome recycling factor OmpH PF03938.14 OWF47425.1 - 3.6 7.9 17.3 7.3 6.9 7.1 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) PTS_2-RNA PF01885.16 OWF47426.1 - 1.7e-21 77.1 0.0 2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Tyrosinase PF00264.20 OWF47427.1 - 3.1e-34 119.2 1.5 6.7e-16 59.3 1.1 2.6 1 1 1 2 2 2 2 Common central domain of tyrosinase Plasmod_dom_1 PF09715.10 OWF47428.1 - 4.3e-13 49.1 301.7 53 4.0 0.6 66.8 1 1 75 76 76 76 71 Plasmodium protein of unknown function (Plasmod_dom_1) Hydin_ADK PF17213.3 OWF47429.1 - 2.5e-73 246.6 2.9 2.5e-73 246.6 2.9 4.7 5 1 1 6 6 6 1 Hydin Adenylate kinase-like domain ASH PF15780.5 OWF47429.1 - 3.3e-59 197.2 33.3 7.3e-08 32.5 0.0 26.9 31 1 1 32 32 32 15 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OWF47429.1 - 4.1e-17 62.0 37.3 0.073 12.9 0.0 17.3 20 0 0 20 20 20 5 MSP (Major sperm protein) domain PapD-like PF14874.6 OWF47429.1 - 7.1e-17 61.4 5.9 0.32 11.2 0.0 12.1 14 0 0 14 14 14 4 Flagellar-associated PapD-like DUF1573 PF07610.11 OWF47429.1 - 2.4e-12 46.7 20.6 0.042 13.9 0.0 14.7 18 0 0 18 18 18 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OWF47429.1 - 2e-05 24.8 20.8 0.02 15.2 0.0 11.6 16 0 0 16 16 16 2 Transmembrane protein 131-like ADK PF00406.22 OWF47429.1 - 0.017 15.2 1.5 5 7.2 0.2 2.5 2 0 0 2 2 2 0 Adenylate kinase PRELI PF04707.14 OWF47430.1 - 4.4e-35 120.8 0.4 5.4e-35 120.5 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family FMO-like PF00743.19 OWF47431.1 - 1.1e-22 80.2 0.0 1.3e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OWF47431.1 - 4.9e-05 23.5 0.0 9.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OWF47431.1 - 0.00019 21.5 0.0 0.00031 20.8 0.0 1.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OWF47431.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF47431.1 - 0.0016 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OWF47431.1 - 0.081 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 OWF47431.1 - 0.086 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SAM_PNT PF02198.16 OWF47431.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Lycopene_cycl PF05834.12 OWF47431.1 - 0.16 10.9 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein AMP-binding_C PF13193.6 OWF47432.1 - 0.011 16.8 11.3 49 5.0 2.0 5.4 1 1 2 3 3 3 0 AMP-binding enzyme C-terminal domain BrnT_toxin PF04365.13 OWF47432.1 - 0.019 15.3 0.1 3 8.3 0.1 2.9 1 1 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system DUF2716 PF10898.8 OWF47432.1 - 0.27 11.6 0.0 1.3e+02 2.9 0.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2716) Drf_FH1 PF06346.12 OWF47433.1 - 0.0088 15.8 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Formin Homology Region 1 DUF5342 PF17277.2 OWF47433.1 - 0.013 15.8 21.8 26 5.3 0.2 7.5 1 1 7 9 9 9 0 Family of unknown function (DUF5342) Baculo_FP PF03258.14 OWF47433.1 - 0.34 11.0 1.3 15 5.7 0.1 3.8 3 2 1 4 4 4 0 Baculovirus FP protein Trypan_PARP PF05887.11 OWF47433.1 - 6 6.9 24.7 1.8e+04 -10.0 24.7 3.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PWI PF01480.17 OWF47434.1 - 0.0017 18.6 0.2 0.0039 17.5 0.2 1.6 1 0 0 1 1 1 1 PWI domain DUF3512 PF12024.8 OWF47434.1 - 0.045 13.2 4.9 0.095 12.2 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Ribosomal_S2 PF00318.20 OWF47434.1 - 0.068 12.4 2.9 0.12 11.5 2.9 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 EF-hand_7 PF13499.6 OWF47435.1 - 6e-09 36.2 11.6 0.0017 18.8 0.1 5.6 5 1 1 6 6 6 2 EF-hand domain pair EF-hand_13 PF17958.1 OWF47435.1 - 2e-06 27.5 0.0 3.1e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 OWF47435.1 - 2.9e-05 23.7 5.2 0.97 9.5 0.0 5.7 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 OWF47435.1 - 0.00058 19.2 0.6 0.22 11.1 0.0 4.8 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.6 OWF47435.1 - 0.027 13.9 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 OWF47435.1 - 0.099 13.0 4.7 4.9 7.5 0.0 2.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GSHPx PF00255.19 OWF47436.1 - 7.3e-21 73.8 0.2 1e-20 73.3 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Ank_2 PF12796.7 OWF47437.1 - 1.8e-49 166.2 3.2 9.6e-16 58.2 0.0 5.6 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF47437.1 - 4.2e-42 142.0 2.5 5.1e-12 46.1 0.1 8.3 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF47437.1 - 1.6e-39 129.3 2.1 3.8e-06 26.8 0.0 9.7 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 OWF47437.1 - 1e-33 114.9 6.7 4.6e-07 30.0 0.0 7.9 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF47437.1 - 7.6e-32 108.4 1.3 1.9e-06 28.1 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat EF-hand_7 PF13499.6 OWF47437.1 - 0.00011 22.6 0.1 0.00024 21.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF47437.1 - 0.00061 19.2 1.0 0.39 10.4 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF47437.1 - 0.0012 18.6 1.1 1.1 9.4 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OWF47437.1 - 0.031 14.1 0.9 0.21 11.5 0.4 2.4 1 1 1 2 2 2 0 EF-hand domain pair NPP1 PF05630.11 OWF47437.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Pkinase PF00069.25 OWF47438.1 - 9.8e-56 189.0 0.1 7.4e-51 173.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF47438.1 - 9.4e-19 67.7 0.1 4.1e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF47438.1 - 6.3e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF47438.1 - 0.0084 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OWF47438.1 - 0.064 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 bZIP_2 PF07716.15 OWF47439.1 - 3.3e-12 46.3 10.8 5.7e-12 45.5 10.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF47439.1 - 0.018 15.2 11.7 0.033 14.3 11.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor LRRC37AB_C PF14914.6 OWF47439.1 - 0.083 12.8 0.7 0.2 11.6 0.7 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain PHD PF00628.29 OWF47440.1 - 9.7e-19 67.0 23.7 1.9e-09 37.2 11.1 2.6 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 OWF47440.1 - 7.2e-05 22.3 2.0 7.2e-05 22.3 2.0 3.6 3 1 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 OWF47440.1 - 0.0036 17.2 2.7 0.0036 17.2 2.7 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Requiem_N PF14051.6 OWF47440.1 - 0.024 14.8 0.1 0.075 13.2 0.1 1.9 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. zf-PHD-like PF15446.6 OWF47440.1 - 0.39 10.3 17.1 0.056 13.1 2.6 3.6 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING_9 PF13901.6 OWF47440.1 - 2.9 7.8 21.7 5.2 7.0 10.1 2.5 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 OWF47440.1 - 8.7 6.3 22.3 0.85 9.6 1.7 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Homeodomain PF00046.29 OWF47443.1 - 7.6e-15 54.5 1.2 7.6e-15 54.5 1.2 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF47443.1 - 3e-05 23.8 0.6 9.4e-05 22.2 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain TFIIE-A_C PF11521.8 OWF47443.1 - 5.6 7.3 6.5 28 5.1 0.1 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Homeodomain PF00046.29 OWF47444.1 - 5.6e-08 32.5 4.1 1.3e-07 31.4 4.1 1.6 1 1 0 1 1 1 1 Homeodomain Viral_env_E26 PF11050.8 OWF47444.1 - 0.073 12.4 0.8 0.1 12.0 0.8 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 ATG_C PF09333.11 OWF47445.1 - 9.2e-30 102.9 0.1 3.5e-29 101.0 0.1 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 OWF47445.1 - 8.9e-20 71.0 0.1 5.6e-19 68.4 0.0 2.4 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OWF47445.1 - 7e-09 35.7 0.0 1.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 OWF47445.1 - 2.6e-05 24.0 4.1 0.00024 20.9 0.2 3.7 3 2 0 3 3 3 1 Autophagy-related protein 2 CAD motif VPS13 PF16908.5 OWF47445.1 - 0.0049 16.7 0.1 0.038 13.8 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VWA PF00092.28 OWF47447.1 - 1.3e-10 41.8 0.0 2.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 OWF47447.1 - 1.8e-05 24.7 0.0 4.1e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A VWA PF00092.28 OWF47448.1 - 0.0059 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Cas_Csy4 PF09618.10 OWF47448.1 - 0.23 11.6 1.8 0.53 10.4 0.3 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Fibrinogen_C PF00147.18 OWF47449.1 - 5.1e-30 104.9 0.7 6.1e-30 104.7 0.7 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Galactosyl_T PF01762.21 OWF47450.1 - 3.1e-68 229.5 7.2 5.5e-40 137.3 0.2 3.1 3 0 0 3 3 3 2 Galactosyltransferase Fringe PF02434.16 OWF47450.1 - 0.0021 17.6 0.1 0.061 12.7 0.0 2.4 2 0 0 2 2 2 1 Fringe-like MraZ PF02381.18 OWF47450.1 - 0.16 12.0 0.0 0.52 10.3 0.0 1.8 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like LRR_4 PF12799.7 OWF47452.1 - 3.4e-56 186.2 91.7 5e-06 26.8 0.6 16.7 9 6 6 17 17 17 16 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF47452.1 - 1.1e-52 178.1 48.6 1.4e-12 47.5 2.9 8.7 4 3 4 8 8 8 8 Leucine-rich repeat LRR_8 PF13855.6 OWF47452.1 - 7.5e-42 140.9 92.7 4.1e-08 32.9 1.5 13.2 8 4 6 15 15 15 14 Leucine rich repeat LRR_5 PF13306.6 OWF47452.1 - 1 9.3 7.4 10 6.1 0.0 4.3 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Snapin_Pallidin PF14712.6 OWF47452.1 - 3.2 8.2 7.2 28 5.2 1.9 3.6 2 0 0 2 2 2 0 Snapin/Pallidin Nuc_sug_transp PF04142.15 OWF47453.1 - 3.6e-33 115.1 21.1 4.4e-33 114.8 21.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OWF47453.1 - 0.019 15.1 29.0 0.075 13.2 4.1 2.5 2 1 0 2 2 2 0 EamA-like transporter family C1q PF00386.21 OWF47454.1 - 1.4e-55 186.9 15.9 1.8e-23 83.2 1.3 3.0 3 0 0 3 3 3 3 C1q domain BclA_C PF18573.1 OWF47454.1 - 4.7e-11 42.7 6.7 0.00063 19.6 1.6 3.2 3 0 0 3 3 3 3 BclA C-terminal domain Peptidase_C2 PF00648.21 OWF47454.1 - 0.008 15.2 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease SH3_9 PF14604.6 OWF47454.1 - 0.032 14.1 0.0 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Variant SH3 domain TTL PF03133.15 OWF47455.1 - 8.4e-31 107.2 0.0 1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF47455.1 - 5.9e-06 25.7 0.0 7.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF47455.1 - 0.066 12.4 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp LRR_6 PF13516.6 OWF47456.1 - 2.4e-06 27.2 12.1 3.7e+02 1.6 0.0 14.4 13 4 3 16 16 16 0 Leucine Rich repeat Ribosomal_TL5_C PF14693.6 OWF47456.1 - 0.00051 20.4 12.9 8.4 6.8 0.4 5.9 1 1 6 7 7 7 3 Ribosomal protein TL5, C-terminal domain Meis_PKNOX_N PF16493.5 OWF47456.1 - 0.016 15.5 27.3 14 6.1 1.3 7.2 1 1 6 7 7 7 0 N-terminal of Homeobox Meis and PKNOX1 GT87 PF09594.10 OWF47456.1 - 0.087 12.5 1.8 66 3.1 0.1 5.6 1 1 1 3 3 3 0 Glycosyltransferase family 87 H-kinase_dim PF02895.14 OWF47456.1 - 0.35 11.3 37.2 19 5.7 3.3 9.1 1 1 4 5 5 5 0 Signal transducing histidine kinase, homodimeric domain DUF4314 PF14192.6 OWF47456.1 - 0.36 10.8 8.3 27 4.8 0.0 5.9 5 3 2 7 7 7 0 Domain of unknown function (DUF4314) TPT PF03151.16 OWF47456.1 - 0.65 9.3 10.2 25 4.1 0.1 5.7 2 2 6 8 8 8 0 Triose-phosphate Transporter family DUF1279 PF06916.13 OWF47456.1 - 1.1 9.9 14.2 35 5.1 0.5 5.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1279) CBM39 PF15886.5 OWF47456.1 - 1.4 8.8 21.0 30 4.6 1.0 6.3 1 1 6 7 7 7 0 Carbohydrate binding domain (family 32) DUF5003 PF16394.5 OWF47456.1 - 2.5 7.1 36.7 2.9 6.9 2.9 5.8 1 1 6 7 7 7 0 Domain of unknown function (DUF5003) DUF1326 PF07040.11 OWF47456.1 - 4 7.4 15.5 8.7 6.3 3.0 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1326) DDE_Tnp_1_6 PF13751.6 OWF47456.1 - 8.2 6.7 34.3 2.9 8.1 1.9 5.8 1 1 4 6 6 6 0 Transposase DDE domain F5_F8_type_C PF00754.25 OWF47457.1 - 1.4e-23 83.3 0.2 2.4e-23 82.6 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain He_PIG PF05345.12 OWF47457.1 - 3e-05 24.1 2.6 6.3e-05 23.1 2.6 1.6 1 0 0 1 1 1 1 Putative Ig domain EGF PF00008.27 OWF47457.1 - 0.00027 21.2 9.6 0.00027 21.2 9.6 1.8 2 0 0 2 2 2 1 EGF-like domain F5_F8_type_C PF00754.25 OWF47458.1 - 1.6e-19 70.3 0.2 2.5e-19 69.6 0.2 1.2 1 0 0 1 1 1 1 F5/8 type C domain EGF PF00008.27 OWF47458.1 - 6.3e-08 32.8 7.5 6.3e-08 32.8 7.5 2.0 2 0 0 2 2 2 1 EGF-like domain He_PIG PF05345.12 OWF47458.1 - 1.3e-05 25.3 0.1 1.3e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 Putative Ig domain hEGF PF12661.7 OWF47458.1 - 0.00015 22.3 4.7 0.00059 20.4 4.7 2.1 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.13 OWF47458.1 - 1.9 9.0 9.5 4.3 7.8 9.5 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.15 OWF47458.1 - 3.2 8.0 11.7 6.4 7.1 11.7 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain F5_F8_type_C PF00754.25 OWF47459.1 - 3.1e-18 66.1 0.0 4.9e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain EGF PF00008.27 OWF47459.1 - 0.0014 18.9 10.7 0.0035 17.6 10.7 1.7 1 0 0 1 1 1 1 EGF-like domain DUF4993 PF16384.5 OWF47459.1 - 0.0086 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function EGF_2 PF07974.13 OWF47459.1 - 0.62 10.5 11.7 1.2 9.5 11.7 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_3 PF12947.7 OWF47459.1 - 1.2 9.4 16.2 0.057 13.6 8.2 2.4 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.15 OWF47459.1 - 1.4 9.2 12.5 2.9 8.2 12.5 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain hEGF PF12661.7 OWF47459.1 - 3.3 8.5 12.5 0.63 10.8 7.8 2.3 1 1 1 2 2 2 0 Human growth factor-like EGF F5_F8_type_C PF00754.25 OWF47460.1 - 6.9e-20 71.4 0.2 1.2e-19 70.7 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain He_PIG PF05345.12 OWF47460.1 - 1.3e-07 31.7 0.5 1.3e-07 31.7 0.5 2.0 2 0 0 2 2 2 1 Putative Ig domain EGF PF00008.27 OWF47460.1 - 0.00052 20.3 11.7 0.00097 19.4 11.7 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 OWF47460.1 - 0.029 15.0 8.4 0.08 13.6 8.4 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_CA PF07645.15 OWF47460.1 - 0.16 12.2 14.3 0.29 11.4 14.3 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain F5_F8_type_C PF00754.25 OWF47461.1 - 9.7e-23 80.7 0.6 1.6e-22 80.0 0.6 1.3 1 0 0 1 1 1 1 F5/8 type C domain EGF PF00008.27 OWF47461.1 - 3.1e-07 30.6 10.8 6.1e-07 29.6 10.8 1.5 1 0 0 1 1 1 1 EGF-like domain He_PIG PF05345.12 OWF47461.1 - 6.3e-07 29.5 0.4 6.3e-07 29.5 0.4 2.8 2 0 0 2 2 2 1 Putative Ig domain hEGF PF12661.7 OWF47461.1 - 0.0026 18.3 5.7 0.0026 18.3 5.7 2.1 2 0 0 2 2 2 1 Human growth factor-like EGF Cadherin PF00028.17 OWF47461.1 - 0.0029 18.0 0.0 0.0074 16.7 0.0 1.6 1 0 0 1 1 1 1 Cadherin domain Laminin_EGF PF00053.24 OWF47461.1 - 0.53 10.5 13.5 1 9.6 13.5 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 OWF47461.1 - 0.72 10.3 14.2 1.6 9.2 14.2 1.6 1 0 0 1 1 1 0 EGF-like domain F5_F8_type_C PF00754.25 OWF47462.1 - 3.2e-21 75.7 0.2 4.9e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 F5/8 type C domain He_PIG PF05345.12 OWF47462.1 - 4.6e-05 23.5 2.0 4.6e-05 23.5 2.0 2.4 2 0 0 2 2 2 1 Putative Ig domain EGF PF00008.27 OWF47462.1 - 0.00019 21.6 9.0 0.00019 21.6 9.0 2.0 1 1 1 2 2 2 1 EGF-like domain FXa_inhibition PF14670.6 OWF47462.1 - 0.094 13.0 11.4 0.54 10.6 6.2 2.5 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 OWF47462.1 - 0.1 12.8 13.5 0.22 11.8 13.5 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain hEGF PF12661.7 OWF47462.1 - 0.16 12.7 10.3 0.11 13.2 7.9 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF PQ-loop PF04193.14 OWF47464.1 - 1.3e-19 69.8 0.0 9.4 6.1 0.0 12.5 5 5 11 16 16 16 10 PQ loop repeat Hydrolase_like PF13242.6 OWF47464.1 - 0.0046 17.0 19.5 1.1e+02 3.0 0.0 11.8 3 3 6 9 9 9 0 HAD-hyrolase-like DUF1013 PF06242.11 OWF47464.1 - 0.88 9.6 4.9 1.2e+02 2.7 0.1 5.4 4 3 1 6 6 6 0 Protein of unknown function (DUF1013) VIT PF08487.10 OWF47465.1 - 1.6e-40 137.7 0.1 5.3e-40 136.1 0.1 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain PARP PF00644.20 OWF47465.1 - 8.8e-33 113.5 1.3 4.5e-32 111.2 1.3 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain VWA_3 PF13768.6 OWF47465.1 - 1.4e-17 64.1 0.0 4.3e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 OWF47465.1 - 1.1e-11 44.4 0.0 3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OWF47465.1 - 2.5e-10 40.9 0.0 6.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain BRCT PF00533.26 OWF47465.1 - 3.9e-10 40.0 0.1 1.5e-09 38.1 0.1 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OWF47465.1 - 3.7e-09 36.9 0.5 2.8e-08 34.0 0.1 2.7 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain VWA_2 PF13519.6 OWF47465.1 - 2.8e-06 27.9 0.0 1.1e-05 26.0 0.0 2.1 2 0 0 2 2 1 1 von Willebrand factor type A domain PTCB-BRCT PF12738.7 OWF47465.1 - 2.1e-05 24.4 0.1 5.4e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 OWF47465.1 - 0.00094 19.4 1.1 0.0018 18.5 0.1 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Ribosomal_60s PF00428.19 OWF47465.1 - 0.0035 17.9 10.5 0.0035 17.9 10.5 3.3 3 0 0 3 3 1 1 60s Acidic ribosomal protein VWA_CoxE PF05762.14 OWF47465.1 - 0.047 13.1 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Snf7 PF03357.21 OWF47466.1 - 2e-17 63.3 15.3 3.2e-17 62.7 15.3 1.4 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 OWF47466.1 - 5.8e-07 29.6 6.6 8.5e-07 29.0 6.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RFX5_N PF18326.1 OWF47466.1 - 0.025 14.4 0.5 0.76 9.6 0.5 2.6 1 1 0 1 1 1 0 RFX5 N-terminal domain DMSP_lyase PF16867.5 OWF47466.1 - 0.1 12.2 0.3 0.22 11.1 0.3 1.5 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase hGDE_central PF14702.6 OWF47466.1 - 0.14 11.8 5.2 0.19 11.4 5.2 1.2 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme ABC2_membrane_3 PF12698.7 OWF47466.1 - 6.7 5.7 5.9 15 4.6 5.9 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Npa1 PF11707.8 OWF47467.1 - 3e-63 214.2 2.8 4.9e-63 213.5 1.1 2.4 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OWF47467.1 - 2.6e-48 164.3 1.5 9.9e-48 162.4 1.5 2.2 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 DUF3861 PF12977.7 OWF47467.1 - 0.13 12.5 0.3 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) Ipi1_N PF12333.8 OWF47467.1 - 1 10.0 4.4 8.4 7.1 0.0 4.8 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Il2rg PF15874.5 OWF47468.1 - 1.9e-13 50.4 0.0 1e-12 48.1 0.0 2.3 2 0 0 2 2 2 1 Putative Interleukin 2 receptor, gamma chain NB-ARC PF00931.22 OWF47468.1 - 5.2e-13 48.8 2.3 1.1e-12 47.7 2.3 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OWF47468.1 - 7.6e-08 32.7 0.2 2.8e-07 30.9 0.2 2.0 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.6 OWF47468.1 - 1.1e-06 28.8 3.8 0.0001 22.5 0.3 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat ATPase_2 PF01637.18 OWF47468.1 - 5.4e-06 26.5 0.1 1.6e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_10 PF13374.6 OWF47468.1 - 0.0009 19.0 0.0 0.0009 19.0 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 OWF47468.1 - 0.0011 19.4 0.1 0.0028 18.1 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OWF47468.1 - 0.0012 19.3 0.0 0.0045 17.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_2 PF07719.17 OWF47468.1 - 0.0036 17.3 0.2 0.0036 17.3 0.2 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat NACHT PF05729.12 OWF47468.1 - 0.0039 17.1 0.5 0.0083 16.1 0.5 1.6 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 OWF47468.1 - 0.0053 16.2 0.0 0.02 14.3 0.0 2.0 1 1 0 1 1 1 1 Bacterial TniB protein TPR_8 PF13181.6 OWF47468.1 - 0.011 15.9 8.0 0.02 15.1 0.3 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF47468.1 - 0.056 13.3 0.3 0.056 13.3 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF47468.1 - 0.087 13.2 0.5 60 4.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF47469.1 - 3.1e-09 37.0 1.1 0.0023 18.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 OWF47469.1 - 5.4e-09 36.7 0.0 1.3e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 OWF47469.1 - 6.3e-09 35.4 2.5 1.4e-06 27.7 0.5 3.0 3 0 0 3 3 3 2 NB-ARC domain AAA PF00004.29 OWF47469.1 - 8.2e-07 29.5 0.0 2.2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OWF47469.1 - 0.00049 20.1 0.3 0.0023 18.0 0.3 2.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OWF47469.1 - 0.017 15.1 0.1 0.037 14.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain TPR_2 PF07719.17 OWF47469.1 - 0.026 14.6 15.1 6.5 7.1 0.3 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat AAA_33 PF13671.6 OWF47469.1 - 0.03 14.5 0.2 0.097 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OWF47469.1 - 0.031 14.8 0.8 0.11 13.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 OWF47469.1 - 0.044 13.8 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ten1_2 PF15490.6 OWF47469.1 - 0.055 13.2 0.0 0.27 10.9 0.0 2.2 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit RuvB_N PF05496.12 OWF47469.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TPR_10 PF13374.6 OWF47469.1 - 0.19 11.6 6.8 3.4 7.7 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat NB-ARC PF00931.22 OWF47470.1 - 1.7e-10 40.5 4.9 1.2e-07 31.2 0.2 3.6 4 0 0 4 4 4 2 NB-ARC domain TPR_12 PF13424.6 OWF47470.1 - 3.1e-10 40.2 2.0 0.00072 19.8 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF47470.1 - 4.7e-10 38.8 4.8 0.00027 20.8 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA PF00004.29 OWF47470.1 - 1.9e-06 28.4 0.0 5.1e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_1 PF00515.28 OWF47470.1 - 2.6e-06 27.0 5.5 0.004 16.9 0.1 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF47470.1 - 1.5e-05 24.7 1.4 0.0031 17.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 OWF47470.1 - 2.5e-05 24.7 0.0 8.2e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain TPR_MalT PF17874.1 OWF47470.1 - 0.0001 21.8 3.3 0.0016 17.9 0.5 2.5 1 1 0 2 2 2 1 MalT-like TPR region AAA_22 PF13401.6 OWF47470.1 - 0.00013 22.3 0.0 0.00038 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_8 PF13181.6 OWF47470.1 - 0.00022 21.2 6.9 0.0089 16.2 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF47470.1 - 0.00072 19.4 4.8 0.47 10.6 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 OWF47470.1 - 0.0014 18.3 0.8 0.092 12.4 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 OWF47470.1 - 0.009 15.7 2.6 0.048 13.4 0.6 2.7 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 OWF47470.1 - 0.037 14.7 2.3 0.39 11.5 0.1 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat AAA_5 PF07728.14 OWF47470.1 - 0.072 13.1 0.0 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TPR_9 PF13371.6 OWF47470.1 - 0.088 13.0 0.5 8.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CbiA PF01656.23 OWF47470.1 - 0.095 12.8 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MIT PF04212.18 OWF47470.1 - 0.12 12.5 0.2 2.4 8.3 0.1 3.1 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain AAA_18 PF13238.6 OWF47470.1 - 0.12 13.0 0.1 0.65 10.5 0.0 2.4 2 0 0 2 2 1 0 AAA domain TPR_16 PF13432.6 OWF47470.1 - 0.13 13.0 0.5 1.3 9.7 0.6 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat ClpS PF02617.17 OWF47470.1 - 0.18 11.6 0.7 7.4 6.4 0.0 2.9 2 1 1 3 3 3 0 ATP-dependent Clp protease adaptor protein ClpS TPR_4 PF07721.14 OWF47470.1 - 0.33 11.7 2.8 3.2 8.6 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Adeno_E4_34 PF04528.13 OWF47471.1 - 1.6e-08 34.5 70.6 4.2 7.2 0.3 12.2 1 1 12 13 13 13 13 Adenovirus early E4 34 kDa protein conserved region PAD_M PF08527.10 OWF47471.1 - 8.6e-07 28.7 35.2 0.38 10.4 1.4 5.3 1 1 4 5 5 5 5 Protein-arginine deiminase (PAD) middle domain IFT20 PF14931.6 OWF47471.1 - 0.0001 22.5 21.9 6.6 6.9 0.3 7.0 1 1 10 11 11 11 11 Intraflagellar transport complex B, subunit 20 DUF5082 PF16888.5 OWF47471.1 - 0.01 16.1 14.5 14 5.9 0.2 5.9 1 1 6 7 7 7 0 Domain of unknown function (DUF5082) PHF5 PF03660.14 OWF47471.1 - 1.3 9.3 63.8 17 5.7 3.0 8.2 1 1 9 10 10 10 0 PHF5-like protein PAD_M PF08527.10 OWF47472.1 - 0.002 17.8 4.2 0.077 12.7 2.0 2.2 1 1 1 2 2 2 2 Protein-arginine deiminase (PAD) middle domain Cor1 PF04803.12 OWF47472.1 - 0.0033 17.7 0.0 16 5.8 0.0 3.5 1 1 3 4 4 4 1 Cor1/Xlr/Xmr conserved region NodZ PF05830.11 OWF47472.1 - 0.013 14.3 7.0 2.9 6.6 0.3 3.6 1 1 3 4 4 4 0 Nodulation protein Z (NodZ) IFT20 PF14931.6 OWF47472.1 - 0.018 15.2 0.8 5.6 7.2 0.1 2.9 1 1 3 4 4 4 0 Intraflagellar transport complex B, subunit 20 Adeno_E4_34 PF04528.13 OWF47472.1 - 0.026 14.4 19.0 1.2 9.0 0.4 4.5 1 1 4 5 5 5 0 Adenovirus early E4 34 kDa protein conserved region Sushi PF00084.20 OWF47472.1 - 0.098 13.3 5.3 8 7.1 0.6 3.2 1 1 2 3 3 3 0 Sushi repeat (SCR repeat) PHF5 PF03660.14 OWF47472.1 - 0.15 12.3 15.7 0.66 10.2 1.3 3.2 1 1 3 4 4 4 0 PHF5-like protein SAM_KSR1 PF13543.6 OWF47472.1 - 0.2 11.8 2.9 5.1 7.3 0.2 3.1 1 1 1 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 Ribosomal_L5e PF17144.4 OWF47472.1 - 0.53 10.3 4.8 22 5.0 0.6 2.8 1 1 3 4 4 4 0 Ribosomal large subunit proteins 60S L5, and 50S L18 MSA-2c PF12238.8 OWF47472.1 - 3.2 7.7 13.0 18 5.3 0.6 3.2 1 1 2 3 3 3 0 Merozoite surface antigen 2c Suf PF05843.14 OWF47472.1 - 7.1 6.5 5.7 1.9e+02 1.8 0.0 3.5 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Biopterin_H PF00351.21 OWF47473.1 - 2.3e-171 569.2 0.0 3.1e-171 568.8 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 OWF47473.1 - 2.8e-08 33.4 0.7 6.4e-08 32.2 0.2 1.9 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 OWF47473.1 - 0.00063 20.3 0.7 0.003 18.1 0.5 2.1 2 0 0 2 2 2 1 ACT domain BrkDBD PF09607.10 OWF47474.1 - 0.00049 19.8 22.8 5.2 6.9 0.3 6.8 1 1 6 7 7 7 7 Brinker DNA-binding domain Spore_YabQ PF09578.10 OWF47474.1 - 4.1 7.7 7.3 60 4.0 0.1 3.8 1 1 3 4 4 4 0 Spore cortex protein YabQ (Spore_YabQ) SCP2 PF02036.17 OWF47475.1 - 7e-21 74.6 0.0 1.3e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Band_7 PF01145.25 OWF47475.1 - 1.5e-15 57.7 0.1 3.7e-15 56.4 0.1 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family SCP2_2 PF13530.6 OWF47475.1 - 0.00054 20.3 0.0 0.0023 18.3 0.0 1.9 2 0 0 2 2 2 1 Sterol carrier protein domain Alkyl_sulf_C PF14864.6 OWF47475.1 - 0.0049 17.1 0.0 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal PAC1 PF16094.5 OWF47476.1 - 4.2e-35 121.3 0.8 4.6e-35 121.2 0.8 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 BSD PF03909.17 OWF47477.1 - 1.8e-16 59.9 1.5 1.8e-16 59.9 1.5 2.4 2 0 0 2 2 2 1 BSD domain DUF1103 PF06513.11 OWF47478.1 - 0.047 13.3 0.2 1 8.9 0.1 2.7 1 1 2 3 3 3 0 Repeat of unknown function (DUF1103) Pox_C7_F8A PF03287.14 OWF47478.1 - 4 7.4 33.3 3.5 7.6 1.0 7.5 1 1 8 9 9 9 0 Poxvirus C7/F8A protein HRM PF02793.22 OWF47479.1 - 9.9 6.5 13.6 22 5.5 2.1 5.5 2 2 1 3 3 3 0 Hormone receptor domain Headcase PF16002.5 OWF47481.1 - 1.3e-82 276.0 6.2 1.3e-82 276.0 6.2 1.6 2 0 0 2 2 2 1 Headcase protein HECA PF15353.6 OWF47481.1 - 9.6e-47 157.4 8.8 2.7e-46 156.0 8.8 1.8 1 0 0 1 1 1 1 Headcase protein family homologue Taxilin PF09728.9 OWF47482.1 - 2.8e-99 332.2 70.1 2.8e-99 332.2 70.1 2.5 2 1 0 2 2 2 1 Myosin-like coiled-coil protein Aldedh PF00171.22 OWF47483.1 - 7.7e-197 654.4 0.0 4.1e-155 516.8 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 OWF47483.1 - 0.00014 21.4 1.7 0.029 13.8 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1487) Adipokin_hormo PF06377.11 OWF47483.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Adipokinetic hormone CTP_synth_N PF06418.14 OWF47484.1 - 1.1e-125 418.3 0.1 1.5e-125 417.9 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OWF47484.1 - 5.3e-54 182.9 0.0 7.9e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OWF47484.1 - 1.9e-06 27.8 0.1 5.5e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 OWF47484.1 - 0.0075 16.3 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2961 PF11175.8 OWF47484.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Lectin_C PF00059.21 OWF47485.1 - 0.00038 21.2 0.1 0.0077 17.0 0.0 2.6 2 0 0 2 2 2 1 Lectin C-type domain PAN_4 PF14295.6 OWF47485.1 - 0.064 13.2 4.7 0.17 11.8 4.7 1.7 1 0 0 1 1 1 0 PAN domain BTB_2 PF02214.22 OWF47486.1 - 7.8e-19 67.8 0.3 2.9e-18 66.0 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain Exonuc_VII_L PF02601.15 OWF47486.1 - 0.00062 19.4 8.1 0.00089 18.9 8.1 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4407 PF14362.6 OWF47486.1 - 0.00074 19.0 5.3 0.0011 18.4 5.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FapA PF03961.13 OWF47486.1 - 0.00087 18.0 8.4 0.00087 18.0 8.4 1.6 1 1 1 2 2 2 1 Flagellar Assembly Protein A Fez1 PF06818.15 OWF47486.1 - 0.00092 19.7 10.8 0.0015 19.0 10.8 1.3 1 0 0 1 1 1 1 Fez1 DUF737 PF05300.11 OWF47486.1 - 0.001 19.5 3.3 0.001 19.5 3.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF737) Filament PF00038.21 OWF47486.1 - 0.0014 18.3 13.0 0.0021 17.7 13.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein BTB_3 PF16017.5 OWF47486.1 - 0.004 17.2 0.1 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Imm70 PF15601.6 OWF47486.1 - 0.0084 15.6 2.6 0.29 10.7 0.0 3.0 3 0 0 3 3 3 1 Immunity protein 70 Rootletin PF15035.6 OWF47486.1 - 0.01 15.9 11.2 0.024 14.7 11.2 1.6 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion HAUS-augmin3 PF14932.6 OWF47486.1 - 0.011 15.4 10.6 0.015 14.8 10.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3584 PF12128.8 OWF47486.1 - 0.019 12.5 11.0 0.028 11.9 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HalX PF08663.10 OWF47486.1 - 0.022 15.1 2.3 0.022 15.1 2.3 3.2 2 1 1 3 3 3 0 HalX domain DUF2884 PF11101.8 OWF47486.1 - 0.024 14.2 9.6 0.041 13.4 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) SOG2 PF10428.9 OWF47486.1 - 0.026 13.7 0.2 0.037 13.2 0.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apolipoprotein PF01442.18 OWF47486.1 - 0.029 14.3 15.5 0.096 12.6 15.4 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 OWF47486.1 - 0.046 12.6 18.2 0.072 12.0 18.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mod_r PF07200.13 OWF47486.1 - 0.077 13.1 19.7 0.076 13.1 10.4 2.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 OWF47486.1 - 0.15 12.1 10.2 1.1 9.3 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 OWF47486.1 - 0.16 11.4 16.3 0.25 10.8 16.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3552 PF12072.8 OWF47486.1 - 0.22 10.9 21.2 0.37 10.2 21.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) AAA_23 PF13476.6 OWF47486.1 - 0.25 11.8 9.0 0.43 11.0 9.0 1.4 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 OWF47486.1 - 0.28 11.5 20.6 0.19 12.1 15.9 2.2 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 OWF47486.1 - 0.33 9.6 11.6 0.45 9.1 11.6 1.2 1 0 0 1 1 1 0 AAA domain KfrA_N PF11740.8 OWF47486.1 - 0.39 11.4 10.8 0.11 13.1 7.1 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Phage_GPO PF05929.11 OWF47486.1 - 0.45 10.1 11.0 0.17 11.5 7.8 1.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase COG2 PF06148.11 OWF47486.1 - 0.68 10.0 9.5 1.3 9.1 9.5 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.21 OWF47486.1 - 0.83 10.2 18.6 1.2 9.7 12.6 2.4 1 1 1 2 2 2 0 Spectrin repeat Cnn_1N PF07989.11 OWF47486.1 - 0.89 9.8 22.8 3.9 7.7 6.5 3.3 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Phasin PF05597.11 OWF47486.1 - 1.1 9.3 12.9 0.11 12.5 4.6 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FUSC-like PF12805.7 OWF47486.1 - 1.4 7.9 6.8 14 4.7 0.0 2.2 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS LMBR1 PF04791.16 OWF47486.1 - 1.6 7.5 4.3 2.1 7.1 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 OWF47486.1 - 1.7 8.7 4.5 22 5.1 4.5 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 OWF47486.1 - 2.2 8.6 19.0 5.2 7.4 18.4 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein NPV_P10 PF05531.12 OWF47486.1 - 2.5 8.6 4.5 29 5.2 3.9 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PV-1 PF06637.11 OWF47486.1 - 3 6.6 13.1 4.5 6.0 13.1 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) YlqD PF11068.8 OWF47486.1 - 3.3 8.1 17.1 12 6.3 2.6 2.3 1 1 1 2 2 2 0 YlqD protein VPS38 PF17649.1 OWF47486.1 - 4.5 6.0 9.9 6.3 5.6 9.9 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 FemAB PF02388.16 OWF47486.1 - 8.1 5.2 11.0 3.8 6.3 8.7 1.5 1 1 0 1 1 1 0 FemAB family Mt_ATP-synt_D PF05873.12 OWF47486.1 - 8.5 6.2 10.7 20 5.0 10.7 1.6 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF4618 PF15397.6 OWF47487.1 - 0.61 9.5 22.8 1 8.7 22.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SH3_9 PF14604.6 OWF47488.1 - 3.8e-44 148.3 5.8 6.3e-15 54.8 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 OWF47488.1 - 1.6e-40 136.5 8.4 1.1e-12 47.3 0.2 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 OWF47488.1 - 5.9e-40 134.7 4.1 3e-13 49.2 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain DUF1640 PF07798.11 OWF47488.1 - 0.0016 18.5 6.9 0.0032 17.5 6.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) UPF0242 PF06785.11 OWF47488.1 - 0.03 14.4 2.8 0.077 13.1 2.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 OWF47488.1 - 0.048 14.3 5.7 0.17 12.6 5.7 1.9 1 0 0 1 1 1 0 Initiation control protein YabA TolA_bind_tri PF16331.5 OWF47488.1 - 0.073 13.2 4.0 0.91 9.7 0.8 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation HALZ PF02183.18 OWF47488.1 - 0.082 13.1 2.4 0.57 10.4 2.0 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 OWF47488.1 - 0.28 11.6 10.4 0.098 13.1 6.3 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Cnn_1N PF07989.11 OWF47488.1 - 0.78 9.9 10.1 0.62 10.3 7.3 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 WD40 PF00400.32 OWF47489.1 - 1.1e-15 57.7 12.4 0.0035 18.2 0.2 8.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF47489.1 - 3.3e-05 24.1 0.0 0.12 12.7 0.0 4.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 OWF47491.1 - 1.2e-08 34.8 1.4 4.9e-08 32.8 0.1 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hydrolase_6 PF13344.6 OWF47493.1 - 1.4e-21 76.5 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OWF47493.1 - 5.5e-17 61.6 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OWF47493.1 - 7e-07 29.7 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OWF47493.1 - 0.0034 17.5 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OWF47493.1 - 0.017 14.8 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VraX PF17412.2 OWF47493.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function Kelch_1 PF01344.25 OWF47493.1 - 0.15 11.6 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 Kelch motif PAE PF03283.13 OWF47494.1 - 2.4e-88 296.6 0.0 3.1e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase Runt PF00853.19 OWF47496.1 - 1.7e-67 224.9 0.0 2.7e-67 224.2 0.0 1.3 1 0 0 1 1 1 1 Runt domain TFIID-18kDa PF02269.16 OWF47497.1 - 9.5e-26 89.7 0.0 2.6e-25 88.2 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit MSA-2c PF12238.8 OWF47497.1 - 0.055 13.5 3.5 0.18 11.8 1.3 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c YccV-like PF08755.11 OWF47499.1 - 2.8e-29 101.5 0.2 4.3e-29 100.9 0.2 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like SH2 PF00017.24 OWF47500.1 - 4.7e-11 42.6 0.0 2.2e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 SH2 domain Cys_rich_FGFR PF00839.17 OWF47501.1 - 0.019 15.1 30.0 78 3.5 0.1 13.1 4 3 12 18 18 18 0 Cysteine rich repeat Pneumovirus_M2 PF06436.11 OWF47501.1 - 0.18 11.3 5.8 39 3.7 0.1 5.5 1 1 4 7 7 7 0 Pneumovirus matrix protein 2 (M2) Prominin PF05478.11 OWF47502.1 - 0.0001 20.5 1.7 0.00013 20.1 1.7 1.1 1 0 0 1 1 1 1 Prominin DUF4795 PF16043.5 OWF47502.1 - 0.0013 18.4 1.1 0.0017 18.0 0.5 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) MCC-bdg_PDZ PF10506.9 OWF47502.1 - 0.0032 17.4 0.9 0.0071 16.3 0.3 1.9 2 0 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome RPAP3_C PF13877.6 OWF47502.1 - 0.0048 17.4 0.3 3.3 8.3 0.0 2.3 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 FlaC_arch PF05377.11 OWF47502.1 - 0.0066 16.8 5.5 0.0093 16.3 1.7 2.7 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) TMCO5 PF14992.6 OWF47502.1 - 0.0078 15.8 4.1 0.012 15.3 4.1 1.3 1 0 0 1 1 1 1 TMCO5 family Wtap PF17098.5 OWF47502.1 - 0.013 15.4 2.4 0.024 14.6 2.4 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family DASH_Spc19 PF08287.11 OWF47502.1 - 0.019 14.9 1.8 0.041 13.8 1.8 1.6 1 0 0 1 1 1 0 Spc19 DUF1825 PF08855.10 OWF47502.1 - 0.02 14.8 0.6 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) TMF_TATA_bd PF12325.8 OWF47502.1 - 0.022 15.0 2.2 0.046 14.0 2.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Herpes_UL6 PF01763.16 OWF47502.1 - 0.023 13.2 2.8 0.031 12.8 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like ZapB PF06005.12 OWF47502.1 - 0.028 14.9 2.9 0.11 12.9 2.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapB DUF4988 PF16378.5 OWF47502.1 - 0.03 14.0 0.3 0.066 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function MctB PF11382.8 OWF47502.1 - 0.033 13.9 0.5 0.049 13.3 0.5 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF2959 PF11172.8 OWF47502.1 - 0.039 14.1 0.5 0.039 14.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DUF4140 PF13600.6 OWF47502.1 - 0.05 14.0 1.6 4 7.9 0.6 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 OWF47502.1 - 0.1 13.2 3.4 0.23 12.0 3.4 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 OWF47502.1 - 0.11 12.6 0.8 0.11 12.6 0.8 2.6 3 0 0 3 3 2 0 bZIP transcription factor Cnn_1N PF07989.11 OWF47502.1 - 0.24 11.6 5.8 0.082 13.1 1.0 2.5 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Troponin PF00992.20 OWF47502.1 - 0.39 11.0 8.1 0.31 11.3 3.0 2.6 2 1 0 2 2 2 0 Troponin Fzo_mitofusin PF04799.13 OWF47502.1 - 0.39 10.2 2.6 0.45 10.1 1.4 1.8 2 0 0 2 2 2 0 fzo-like conserved region TMF_DNA_bd PF12329.8 OWF47502.1 - 0.4 10.7 5.6 5.7 7.0 3.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 OWF47502.1 - 0.41 10.8 4.9 0.21 11.7 0.6 2.6 2 1 1 3 3 3 0 Basic region leucine zipper ADIP PF11559.8 OWF47502.1 - 0.49 10.5 9.8 0.041 14.0 4.5 1.9 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 OWF47502.1 - 0.55 10.4 4.2 0.66 10.2 3.1 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Shugoshin_N PF07558.11 OWF47502.1 - 1.8 8.5 6.6 0.21 11.5 0.6 2.7 3 1 0 3 3 2 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 OWF47502.1 - 3.6 8.0 6.5 0.55 10.6 1.1 2.5 3 1 1 4 4 3 0 TSC-22/dip/bun family Kelch_6 PF13964.6 OWF47503.1 - 0.15 12.4 12.5 11 6.5 1.4 5.2 1 1 4 5 5 5 0 Kelch motif DUF3954 PF13128.6 OWF47503.1 - 9.6 6.1 9.1 4.1 7.3 0.2 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3954) DUF3954 PF13128.6 OWF47506.1 - 0.003 17.3 4.2 0.48 10.3 0.2 3.1 1 1 1 3 3 3 2 Protein of unknown function (DUF3954) GARS_C PF02843.16 OWF47506.1 - 2.2 8.6 10.0 1.6e+03 -0.5 10.0 3.7 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain GN3L_Grn1 PF08701.11 OWF47507.1 - 2.9 8.0 13.0 14 5.9 0.0 4.7 1 1 2 3 3 3 0 GNL3L/Grn1 putative GTPase MFS_1 PF07690.16 OWF47509.1 - 2.5e-29 102.3 49.0 9.8e-27 93.8 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.24 OWF47510.1 - 1.5e-129 433.2 0.0 3.8e-129 431.9 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 OWF47510.1 - 5.6e-18 65.1 0.0 3.8e-17 62.4 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 OWF47510.1 - 4.7e-13 49.2 0.5 1e-12 48.1 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF47510.1 - 3.3e-08 33.5 0.0 3.2e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF47510.1 - 2.6e-07 30.2 0.4 4.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OWF47510.1 - 3.7e-06 26.4 0.1 7.8e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OWF47510.1 - 1.8e-05 24.0 1.5 3.3e-05 23.2 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OWF47510.1 - 0.00029 20.1 0.2 0.00059 19.1 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OWF47510.1 - 0.00042 19.1 1.2 0.00042 19.1 1.2 2.1 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OWF47510.1 - 0.00056 19.3 1.0 0.0014 17.9 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain DUF489 PF04356.12 OWF47510.1 - 0.001 19.1 0.9 0.0023 18.0 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF489) FAD_oxidored PF12831.7 OWF47510.1 - 0.0038 16.6 2.7 0.0038 16.6 2.7 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OWF47510.1 - 0.005 17.4 0.9 0.005 17.4 0.9 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF47510.1 - 0.0071 15.6 1.3 0.015 14.6 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF47510.1 - 0.015 14.4 1.2 0.015 14.4 1.2 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OWF47510.1 - 0.026 13.6 0.2 0.041 12.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Vps16_C PF04840.12 OWF47510.1 - 0.05 12.6 4.1 0.078 12.0 4.1 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region 2-Hacid_dh_C PF02826.19 OWF47510.1 - 0.13 11.6 1.4 0.15 11.4 0.2 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DNA_topoisoIV PF00521.20 OWF47510.1 - 0.7 8.7 4.7 1.1 8.1 4.7 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A CAP_N PF01213.19 OWF47510.1 - 2.3 7.6 11.2 6.8 6.1 0.6 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF349 PF03993.12 OWF47510.1 - 8.8 6.7 11.7 1.5 9.2 5.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Ras PF00071.22 OWF47511.1 - 1.1e-32 112.9 0.0 1.3e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47511.1 - 5e-08 33.2 0.1 1.4e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OWF47511.1 - 0.00095 19.1 0.1 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_19 PF13245.6 OWF47511.1 - 0.014 15.7 1.5 0.13 12.6 0.3 2.2 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 OWF47511.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 OWF47511.1 - 0.033 13.9 0.3 0.1 12.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF47511.1 - 0.074 13.4 0.2 0.11 12.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OWF47511.1 - 0.094 13.0 0.2 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Xpo1 PF08389.12 OWF47512.1 - 6.6e-23 81.4 6.6 1.2e-21 77.3 1.0 3.8 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.19 OWF47512.1 - 0.0002 21.2 0.1 0.0006 19.7 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF5110 PF17137.4 OWF47515.1 - 0.0031 17.7 0.0 35 4.8 0.0 4.9 1 1 4 5 5 5 1 Domain of unknown function (DUF5110) GH43_C2 PF17851.1 OWF47515.1 - 8.5 6.0 19.8 7.8 6.2 1.1 4.7 1 1 3 5 5 5 0 Beta xylosidase C-terminal Concanavalin A-like domain Phage_antiter_Q PF06323.11 OWF47516.1 - 2.5e-08 33.7 18.0 0.35 10.4 0.1 7.8 3 2 6 10 10 10 9 Phage antitermination protein Q MliC PF09864.9 OWF47516.1 - 0.78 9.7 1.8 35 4.4 0.0 4.4 5 2 0 6 6 6 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme SAMP PF05924.11 OWF47516.1 - 6.4 6.2 20.0 1.6e+02 1.8 0.0 9.8 13 0 0 13 13 13 0 SAMP Motif DEAD PF00270.29 OWF47517.1 - 1.1e-49 168.5 0.3 5.8e-49 166.2 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF47517.1 - 2.1e-28 98.9 3.2 1e-27 96.7 0.1 3.2 4 1 1 5 5 5 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OWF47517.1 - 0.003 17.9 5.4 0.012 15.9 0.1 3.4 3 2 0 3 3 3 1 AAA domain MCM2_N PF12619.8 OWF47517.1 - 0.096 13.0 2.4 0.18 12.1 2.4 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Ank PF00023.30 OWF47518.1 - 1e-21 76.3 1.5 2e-07 31.1 0.0 5.4 5 1 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 OWF47518.1 - 1.1e-21 77.2 0.3 6.6e-10 39.4 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF47518.1 - 1.6e-20 71.0 0.6 0.00016 21.9 0.0 5.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OWF47518.1 - 2e-20 72.9 1.4 1.4e-10 41.5 0.0 4.2 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF47518.1 - 3e-13 49.7 0.5 0.00016 21.9 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF47518.1 - 2.3e-07 31.0 0.8 5.5e-07 29.8 0.8 1.6 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 OWF47519.1 - 0.066 13.8 0.0 1.4 9.6 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ion_trans_2 PF07885.16 OWF47520.1 - 6.1e-37 125.4 16.7 1.7e-19 69.6 1.2 2.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF47520.1 - 6.7e-08 32.1 2.1 0.0056 16.0 0.3 2.2 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 OWF47521.1 - 6e-37 125.5 13.7 5.6e-20 71.1 1.0 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 OWF47521.1 - 4.6e-09 35.9 0.1 0.00095 18.5 0.0 2.3 2 0 0 2 2 2 2 Ion transport protein Cwf_Cwc_15 PF04889.12 OWF47521.1 - 2.7 7.7 4.9 4.1 7.1 4.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Adaptin_N PF01602.20 OWF47522.1 - 8.7e-174 578.9 16.8 1.1e-173 578.6 16.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.6 OWF47522.1 - 5.9e-46 156.4 0.4 1.5e-45 155.1 0.4 1.8 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.7 OWF47522.1 - 3.2e-25 89.1 11.0 1.5e-20 73.9 0.8 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OWF47522.1 - 4.2e-10 39.9 1.0 2.3e-05 24.7 0.1 4.0 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 OWF47522.1 - 2.8e-05 24.0 2.3 1.1 9.7 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 OWF47522.1 - 0.022 15.3 0.5 5 7.7 0.0 4.3 4 1 0 4 4 4 0 HEAT-like repeat BUD22 PF09073.10 OWF47522.1 - 0.05 12.9 57.2 0.055 12.8 50.4 2.1 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 OWF47522.1 - 1.7 8.0 54.7 0.73 9.2 45.3 2.2 2 0 0 2 2 2 0 SDA1 SCAMP PF04144.13 OWF47523.1 - 1.3e-53 181.9 16.6 1.5e-53 181.6 16.6 1.1 1 0 0 1 1 1 1 SCAMP family OmpH PF03938.14 OWF47523.1 - 0.62 10.4 7.4 1.1 9.5 7.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Conotoxin PF02950.17 OWF47523.1 - 1.4 10.0 3.3 9.1 7.4 1.2 2.3 2 0 0 2 2 2 0 Conotoxin UPF0242 PF06785.11 OWF47523.1 - 3.5 7.7 6.9 1.8 8.6 1.9 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1168 PF06658.12 OWF47524.1 - 1.4 8.8 29.4 0.23 11.3 7.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1168) MIP PF00230.20 OWF47525.1 - 9.4e-54 182.5 7.5 1.2e-53 182.2 7.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 OWF47526.1 - 2.9e-49 167.8 5.2 3.3e-49 167.6 5.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Myosin_head PF00063.21 OWF47527.1 - 2.3e-219 730.1 1.9 2.8e-219 729.8 1.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) SH2 PF00017.24 OWF47527.1 - 1.5e-15 57.1 0.1 4.7e-15 55.5 0.1 2.0 1 0 0 1 1 1 1 SH2 domain IQ PF00612.27 OWF47527.1 - 0.00018 21.0 0.3 0.0006 19.4 0.3 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_22 PF13401.6 OWF47527.1 - 0.017 15.4 0.0 0.068 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OWF47527.1 - 0.021 15.3 0.0 0.083 13.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OWF47527.1 - 0.04 14.3 0.1 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 OWF47527.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Orn_Arg_deC_N PF02784.16 OWF47530.1 - 1.5e-49 168.6 0.0 2.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF47530.1 - 1e-11 44.9 0.3 1.1e-10 41.6 0.0 2.4 3 0 0 3 3 3 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF1863 PF08937.11 OWF47530.1 - 0.022 15.1 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Sugar_tr PF00083.24 OWF47531.1 - 2.6e-28 99.1 9.2 8.1e-28 97.5 9.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF47531.1 - 6.2e-24 84.6 6.9 9.1e-24 84.0 6.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OWF47531.1 - 3.8e-05 22.3 6.7 0.00023 19.7 2.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OWF47532.1 - 1e-31 110.3 11.6 1.8e-29 102.9 11.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF47532.1 - 8.9e-29 100.5 45.3 6.9e-22 77.8 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pico_P2B PF01552.17 OWF47532.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Picornavirus 2B protein BLOC1_2 PF10046.9 OWF47534.1 - 0.0018 18.5 2.8 0.003 17.8 2.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 OWF47534.1 - 0.018 15.5 2.8 0.027 14.9 2.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CALCOCO1 PF07888.11 OWF47534.1 - 0.12 11.2 1.9 0.16 10.8 1.9 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spectrin PF00435.21 OWF47534.1 - 0.12 12.8 1.2 0.19 12.2 1.2 1.1 1 0 0 1 1 1 0 Spectrin repeat Tup_N PF08581.10 OWF47534.1 - 0.22 11.9 2.6 0.37 11.1 2.6 1.2 1 0 0 1 1 1 0 Tup N-terminal CLZ PF16526.5 OWF47534.1 - 0.29 11.5 1.2 0.49 10.8 1.2 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CCDC158 PF15921.5 OWF47534.1 - 0.38 8.5 1.7 0.47 8.2 1.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 GIT_CC PF16559.5 OWF47534.1 - 7.1 6.6 9.0 17 5.4 2.4 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Arf PF00025.21 OWF47535.1 - 1e-33 116.2 0.0 1.4e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF47535.1 - 4.8e-10 39.2 0.0 6.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OWF47535.1 - 5.9e-07 29.7 0.0 8.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF47535.1 - 2.1e-05 24.2 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OWF47535.1 - 0.00066 18.9 0.4 0.079 12.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit ABC_tran PF00005.27 OWF47535.1 - 0.029 14.9 0.0 0.051 14.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 OWF47535.1 - 0.048 13.8 0.0 0.36 10.9 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF47535.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OWF47535.1 - 0.098 12.4 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OWF47535.1 - 0.19 11.4 0.0 3.9 7.2 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SMAP PF15477.6 OWF47537.1 - 3e-14 53.7 2.4 3e-14 53.7 2.4 4.5 2 1 0 2 2 2 1 Small acidic protein family UQ_con PF00179.26 OWF47539.1 - 3.2e-11 43.0 0.0 2.2e-10 40.3 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF47539.1 - 0.0032 17.7 1.0 0.038 14.3 0.2 2.5 2 1 0 2 2 2 1 RWD domain CDC45 PF02724.14 OWF47539.1 - 0.015 13.6 2.3 0.021 13.2 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 OWF47539.1 - 0.022 13.7 1.0 0.034 13.1 1.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 OWF47539.1 - 0.064 11.8 1.5 0.068 11.7 1.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 OWF47539.1 - 0.55 11.2 12.2 1.2 10.1 12.2 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2457 PF10446.9 OWF47539.1 - 3 6.9 12.5 4.5 6.3 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPRCAP PF15713.5 OWF47539.1 - 6.4 7.1 8.9 10 6.4 8.9 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 OWF47539.1 - 9.1 4.2 13.7 13 3.8 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi WRNPLPNID PF15017.6 OWF47540.1 - 0.9 10.5 3.2 1.1 10.2 0.1 2.3 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box TIG PF01833.24 OWF47541.1 - 7.7e-10 38.7 0.8 7.7e-10 38.7 0.8 1.9 2 0 0 2 2 2 1 IPT/TIG domain C2 PF00168.30 OWF47541.1 - 2.2e-08 34.3 0.1 4.8e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 C2 domain RBD-FIP PF09457.10 OWF47541.1 - 0.016 15.1 3.2 0.049 13.6 0.4 2.4 2 0 0 2 2 2 0 FIP domain DivIC PF04977.15 OWF47541.1 - 0.37 10.6 2.4 0.85 9.4 2.4 1.5 1 0 0 1 1 1 0 Septum formation initiator F5_F8_type_C PF00754.25 OWF47542.1 - 2.8e-18 66.2 0.2 4.9e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 F5/8 type C domain PAN_3 PF08277.12 OWF47542.1 - 0.00085 19.1 1.9 0.0018 18.0 1.9 1.5 1 0 0 1 1 1 1 PAN-like domain adh_short PF00106.25 OWF47543.1 - 0.00013 21.5 0.0 0.00014 21.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 OWF47544.1 - 5.4e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Cu2_monoox_C PF03712.15 OWF47545.1 - 8.2e-25 87.1 0.2 1.5e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF47545.1 - 4.5e-18 65.7 0.1 9.9e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monooxygen PF01082.20 OWF47546.1 - 1.2e-21 77.3 0.0 2.5e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain I-set PF07679.16 OWF47547.1 - 2.7e-39 133.1 0.1 2e-14 53.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF47547.1 - 7.8e-35 119.3 4.6 6.2e-12 46.0 0.2 3.5 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 OWF47547.1 - 5.9e-25 87.3 0.2 6.1e-09 35.9 0.1 3.7 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF47547.1 - 6.2e-22 77.7 0.2 1.2e-07 32.0 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF47547.1 - 2.3e-15 56.7 1.1 2e-06 27.9 0.0 4.2 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF47547.1 - 0.0012 18.9 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 OWF47547.1 - 0.0017 18.7 4.9 0.026 14.9 0.1 3.1 4 0 0 4 4 3 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 OWF47547.1 - 0.0035 16.9 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 OWF47547.1 - 0.0038 17.4 1.9 9.6 6.6 0.5 4.4 3 2 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 OWF47547.1 - 0.029 14.4 0.1 1 9.4 0.0 2.6 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF47547.1 - 0.057 13.4 0.0 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 C17orf99 Ig domain SOUL PF04832.12 OWF47548.1 - 7.1e-41 140.2 0.5 8.2e-41 140.0 0.5 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein Glyoxalase_4 PF13669.6 OWF47549.1 - 1.4e-20 73.6 0.0 1.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 OWF47549.1 - 1e-10 41.9 0.0 1.4e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OWF47549.1 - 8e-09 35.9 0.0 9.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OWF47549.1 - 0.16 12.8 0.0 0.23 12.3 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Tim44 PF04280.15 OWF47550.1 - 9.6e-41 139.3 0.2 2.8e-40 137.8 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain PIN_8 PF18476.1 OWF47550.1 - 6.2 6.6 14.5 0.37 10.6 6.9 2.2 1 1 0 2 2 2 0 PIN like domain DUF2039 PF10217.9 OWF47551.1 - 3e-28 98.0 17.3 4e-28 97.6 15.3 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 OWF47551.1 - 0.12 12.4 11.7 0.06 13.3 9.0 1.9 2 0 0 2 2 2 0 zinc-ribbons Cwf_Cwc_15 PF04889.12 OWF47551.1 - 1.2 8.8 11.9 0.1 12.3 7.3 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cript PF10235.9 OWF47551.1 - 5 7.8 15.8 36 5.0 15.8 2.4 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Hydrolase_4 PF12146.8 OWF47552.1 - 4.9e-13 48.9 0.1 3.3e-07 29.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF47552.1 - 9.5e-09 36.2 0.8 7.8e-06 26.6 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF47552.1 - 4.7e-07 29.7 0.3 0.02 14.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47552.1 - 3.5e-06 26.6 0.0 0.00021 20.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OWF47552.1 - 8.8e-05 22.2 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 OWF47552.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 OWF47552.1 - 0.0033 16.5 0.2 0.0069 15.4 0.1 1.5 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 OWF47552.1 - 0.009 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OWF47552.1 - 0.039 13.7 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 OWF47552.1 - 0.14 12.1 0.0 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) EGF_CA PF07645.15 OWF47553.1 - 0 1017.6 724.6 2.9e-11 43.4 5.2 46.9 46 2 2 48 48 48 43 Calcium-binding EGF domain cEGF PF12662.7 OWF47553.1 - 1.3e-219 709.2 401.3 4.6e-10 39.2 0.7 49.2 47 0 0 47 47 47 45 Complement Clr-like EGF-like TB PF00683.17 OWF47553.1 - 2.5e-108 353.6 135.2 1.9e-14 53.1 9.1 11.4 9 0 0 9 9 9 9 TB domain EGF PF00008.27 OWF47553.1 - 1.3e-101 332.3 661.4 0.00021 21.5 10.1 48.2 47 0 0 47 47 47 43 EGF-like domain FXa_inhibition PF14670.6 OWF47553.1 - 8.9e-95 310.7 687.7 6e-11 42.4 6.4 47.3 44 3 3 47 47 47 42 Coagulation Factor Xa inhibitory site hEGF PF12661.7 OWF47553.1 - 3e-80 262.4 663.7 0.0001 22.8 7.5 51.0 50 1 0 50 50 50 39 Human growth factor-like EGF EGF_3 PF12947.7 OWF47553.1 - 4e-42 142.1 624.2 2.5e-11 43.6 9.7 47.4 46 2 1 47 47 47 35 EGF domain Plasmod_Pvs28 PF06247.11 OWF47553.1 - 4.8e-22 78.0 509.0 0.0016 18.7 3.0 45.4 40 4 4 44 44 44 27 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 OWF47553.1 - 0.0012 18.9 5.1 0.0012 18.9 5.1 42.4 44 0 0 44 44 44 14 MSP1 EGF domain 1 Cadherin PF00028.17 OWF47553.1 - 0.21 12.0 0.0 0.45 11.0 0.0 1.4 1 0 0 1 1 1 0 Cadherin domain Cu2_monoox_C PF03712.15 OWF47554.1 - 7e-41 139.3 0.0 1.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF47554.1 - 3.7e-28 98.4 0.1 6.7e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Fibrinogen_C PF00147.18 OWF47555.1 - 1.3e-49 169.0 6.8 1.6e-49 168.7 6.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF47555.1 - 0.0075 16.2 3.7 0.014 15.4 3.7 1.5 1 0 0 1 1 1 1 PAN domain TPR_1 PF00515.28 OWF47556.1 - 1.2e-15 56.5 5.0 0.0002 21.0 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF47556.1 - 4.5e-15 54.5 0.4 0.00015 21.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF47556.1 - 2.8e-08 33.3 0.2 0.0002 20.9 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 OWF47556.1 - 4.1e-06 27.0 0.2 0.96 9.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat CS PF04969.16 OWF47556.1 - 8.9e-06 26.6 0.0 1.8e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_8 PF13181.6 OWF47556.1 - 5.3e-05 23.1 0.4 0.22 11.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF47556.1 - 0.00011 22.3 0.2 0.61 10.3 0.0 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF47556.1 - 0.00025 21.5 1.2 0.0049 17.4 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF47556.1 - 0.00034 21.2 0.3 0.0011 19.6 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF47556.1 - 0.018 15.8 0.0 0.19 12.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF47556.1 - 0.29 11.6 1.6 21 5.8 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4518 PF15008.6 OWF47557.1 - 5.8e-85 284.8 0.0 7.5e-85 284.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) HMG-CoA_red PF00368.18 OWF47558.1 - 1.3e-144 481.7 0.1 1.8e-144 481.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 OWF47558.1 - 2.2e-16 60.1 2.0 5e-16 58.9 2.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OWF47558.1 - 5.3e-07 28.1 0.0 8.8e-07 27.4 0.0 1.3 1 0 0 1 1 1 1 Patched family ACR_tran PF00873.19 OWF47558.1 - 0.012 13.4 0.1 0.017 12.8 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Myosin_head PF00063.21 OWF47559.1 - 7.8e-173 576.3 15.2 9e-140 467.0 11.6 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) RhoGAP PF00620.27 OWF47559.1 - 5.8e-44 149.6 0.1 2.3e-43 147.7 0.1 2.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 OWF47559.1 - 1.5e-06 28.0 9.3 4.4e-06 26.5 9.3 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) IQ PF00612.27 OWF47559.1 - 7.5e-06 25.3 23.8 0.0069 16.1 0.6 4.9 4 0 0 4 4 4 3 IQ calmodulin-binding motif Zf_RING PF16744.5 OWF47559.1 - 0.86 9.8 6.5 2.9 8.1 6.5 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_9 PF13901.6 OWF47559.1 - 4.5 7.2 11.9 1.9 8.4 7.4 2.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon I-set PF07679.16 OWF47560.1 - 3.1e-07 30.4 0.0 6.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF47560.1 - 1.5e-05 25.1 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain MMR_HSR1 PF01926.23 OWF47560.1 - 1.9e-05 24.7 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ig_3 PF13927.6 OWF47560.1 - 3.5e-05 24.3 0.1 7.6e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 OWF47560.1 - 6e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 OWF47560.1 - 0.0012 19.0 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 RsgA_GTPase PF03193.16 OWF47560.1 - 0.0022 17.9 0.1 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OWF47560.1 - 0.011 15.1 0.1 0.023 14.0 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OWF47560.1 - 0.019 14.5 0.0 0.047 13.2 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 OWF47560.1 - 0.028 14.5 0.8 1.1 9.3 0.0 2.5 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 OWF47560.1 - 0.036 13.6 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 OWF47560.1 - 0.045 13.3 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OWF47560.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OWF47560.1 - 0.064 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PHR PF08005.12 OWF47561.1 - 1.7e-52 178.1 1.3 1.7e-52 178.1 1.3 2.2 2 1 0 2 2 2 1 PHR domain AAA PF00004.29 OWF47562.1 - 1.3e-06 28.8 0.4 0.017 15.6 0.2 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF47562.1 - 0.0031 17.5 0.1 0.23 11.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF47562.1 - 0.013 15.8 0.0 12 6.2 0.0 3.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OWF47562.1 - 0.023 15.2 0.2 0.25 11.8 0.0 2.9 3 0 0 3 3 3 0 ABC transporter F-box-like PF12937.7 OWF47565.1 - 0.002 17.9 0.4 0.002 17.9 0.4 3.1 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.6 OWF47565.1 - 0.035 14.2 7.5 33 4.9 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich repeat F-box PF00646.33 OWF47565.1 - 0.095 12.6 10.2 0.034 14.0 2.8 3.6 3 0 0 3 3 3 0 F-box domain DUF3712 PF12505.8 OWF47565.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) LRR_4 PF12799.7 OWF47565.1 - 0.18 12.3 20.5 0.064 13.7 4.3 6.6 8 1 1 9 9 9 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF47565.1 - 0.19 11.5 8.9 1 9.2 0.1 4.8 5 1 0 5 5 5 0 Leucine rich repeat Ank_2 PF12796.7 OWF47566.1 - 4.1e-20 72.1 1.8 6.4e-05 23.5 0.0 5.8 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF47566.1 - 2e-12 47.1 7.2 0.0026 18.0 0.1 7.2 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF47566.1 - 7.9e-11 42.3 1.3 0.15 12.7 0.0 6.9 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF47566.1 - 8.6e-06 25.7 4.6 0.13 12.9 0.0 6.9 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 OWF47566.1 - 1.4e-05 25.3 2.2 0.69 10.5 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat ResIII PF04851.15 OWF47566.1 - 0.028 14.4 0.5 0.064 13.3 0.5 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF47566.1 - 0.029 14.7 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OWF47566.1 - 0.029 13.6 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 OWF47566.1 - 0.052 12.8 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ploopntkinase2 PF18747.1 OWF47566.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 AAA_19 PF13245.6 OWF47566.1 - 0.12 12.7 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.29 OWF47567.1 - 1.6e-12 47.1 5.3 3.2e-06 26.9 0.0 5.3 5 1 0 5 5 5 3 KH domain KH_2 PF07650.17 OWF47567.1 - 0.0011 18.8 0.5 5.5 6.9 0.0 4.3 4 1 0 4 4 4 2 KH domain DUF5061 PF16587.5 OWF47567.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein Parvo_NS1 PF01057.17 OWF47567.1 - 0.087 11.9 0.4 1.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Parvovirus non-structural protein NS1 Spt5-NGN PF03439.13 OWF47567.1 - 0.098 12.6 1.5 11 6.0 0.1 3.6 3 0 0 3 3 3 0 Early transcription elongation factor of RNA pol II, NGN section Yippee-Mis18 PF03226.14 OWF47568.1 - 5.8e-24 84.3 0.6 8.6e-24 83.8 0.6 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OWF47568.1 - 0.015 15.5 0.2 0.033 14.4 0.2 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I SelR PF01641.18 OWF47568.1 - 0.054 13.6 0.2 1.4 9.0 0.2 2.2 1 1 0 1 1 1 0 SelR domain cNMP_binding PF00027.29 OWF47569.1 - 1.3e-22 79.6 0.1 2.2e-12 46.9 0.1 3.2 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Fibrinogen_BP PF08017.11 OWF47571.1 - 3e-05 22.6 0.2 3.7e-05 22.3 0.2 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein DUF2345 PF10106.9 OWF47571.1 - 0.0003 20.7 9.4 1.6 8.6 0.3 3.2 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) CopB PF05275.11 OWF47571.1 - 0.0055 16.3 1.7 1.5 8.4 0.0 3.2 1 1 0 3 3 3 1 Copper resistance protein B precursor (CopB) Exop_C PF18559.1 OWF47571.1 - 0.023 14.6 8.8 3.1 7.6 0.4 3.1 1 1 2 3 3 3 0 Galactose-binding domain-like Neur_chan_LBD PF02931.23 OWF47571.1 - 0.04 13.4 8.0 0.69 9.3 2.5 3.1 1 1 2 3 3 3 0 Neurotransmitter-gated ion-channel ligand binding domain OMP_b-brl_3 PF14905.6 OWF47571.1 - 0.047 12.7 9.5 0.033 13.2 1.7 2.4 1 1 1 2 2 2 0 Outer membrane protein beta-barrel family DUF2807 PF10988.8 OWF47571.1 - 0.055 13.3 29.5 3.2 7.5 29.2 3.3 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Bactofilin PF04519.13 OWF47571.1 - 0.27 11.6 19.7 6.2 7.2 3.0 3.5 1 1 2 3 3 3 0 Polymer-forming cytoskeletal PH_3 PF14593.6 OWF47571.1 - 0.54 10.4 9.1 25 5.0 0.4 4.5 1 1 3 4 4 4 0 PH domain DUF1943 PF09172.11 OWF47571.1 - 1.2 8.4 26.9 32 3.6 12.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) DUF4891 PF16232.5 OWF47571.1 - 6.1 7.4 19.9 26 5.4 0.1 5.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4891) Apc13p PF05839.11 OWF47571.1 - 6.1 7.1 22.5 6.1 7.1 0.9 5.0 1 1 5 6 6 6 0 Apc13p protein ASC PF00858.24 OWF47571.1 - 10 5.0 8.4 5.6e+02 -0.8 8.4 2.9 1 1 0 1 1 1 0 Amiloride-sensitive sodium channel IBR PF01485.21 OWF47572.1 - 1.1 9.5 5.1 8 6.8 5.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Fibrinogen_BP PF08017.11 OWF47573.1 - 3.2e-17 62.0 59.7 3.4e-08 32.3 5.0 3.0 1 1 2 3 3 3 3 Fibrinogen binding protein DUF2345 PF10106.9 OWF47573.1 - 0.0064 16.4 25.7 0.015 15.2 4.8 4.9 2 1 4 6 6 6 4 Uncharacterized protein conserved in bacteria (DUF2345) SIS_2 PF13580.6 OWF47573.1 - 0.43 10.6 12.0 1 9.3 0.3 4.2 1 1 5 6 6 6 0 SIS domain Fibrinogen_BP PF08017.11 OWF47574.1 - 3.3e-09 35.7 24.4 4.3e-09 35.3 24.4 1.2 1 0 0 1 1 1 1 Fibrinogen binding protein DUF2345 PF10106.9 OWF47574.1 - 4.3e-05 23.4 12.3 0.07 13.0 0.7 3.7 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2345) UvrD_C_2 PF13538.6 OWF47574.1 - 5.4e-05 22.9 0.8 6.4 6.7 0.0 5.2 4 2 2 6 6 6 1 UvrD-like helicase C-terminal domain Ntox50 PF15542.6 OWF47574.1 - 0.0088 16.8 19.7 8.5 7.3 2.2 5.1 1 1 3 4 4 4 2 Bacterial toxin 50 SIS_2 PF13580.6 OWF47574.1 - 0.54 10.3 4.0 6 6.9 0.1 2.7 2 1 1 3 3 3 0 SIS domain PmrD PF11183.8 OWF47574.1 - 0.77 9.9 14.8 12 6.2 0.1 5.7 2 1 3 6 6 6 0 Polymyxin resistance protein PmrD Fer4_21 PF14697.6 OWF47574.1 - 3.7 7.8 11.6 42 4.4 0.3 4.9 1 1 4 6 6 6 0 4Fe-4S dicluster domain tRNA-synt_1b PF00579.25 OWF47575.1 - 7.1e-65 219.2 0.0 8.7e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) LRR_8 PF13855.6 OWF47576.1 - 7.5e-82 269.0 64.2 1.9e-13 49.9 0.0 12.1 7 3 6 13 13 13 12 Leucine rich repeat LRR_4 PF12799.7 OWF47576.1 - 4.2e-36 122.4 65.7 7e-05 23.1 0.7 12.9 8 3 5 15 15 15 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF47576.1 - 1.8e-28 99.1 11.9 3.1e-07 30.4 0.0 6.3 4 1 1 6 6 6 6 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 OWF47576.1 - 2.8e-18 66.6 0.2 9.2e-18 65.0 0.2 1.9 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF47576.1 - 9.5e-18 64.6 0.7 2.3e-17 63.4 0.7 1.6 1 1 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF47576.1 - 5.1e-12 45.6 26.2 0.0012 18.4 0.2 7.1 2 2 5 8 8 8 6 Leucine-rich repeat LRR_1 PF00560.33 OWF47576.1 - 0.00012 22.1 45.9 19 6.3 0.2 16.9 17 1 0 17 17 17 0 Leucine Rich Repeat DUF1863 PF08937.11 OWF47576.1 - 0.00075 19.8 0.9 0.0035 17.7 0.9 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRRNT PF01462.18 OWF47576.1 - 0.007 16.0 3.3 0.007 16.0 3.3 4.2 3 0 0 3 3 3 2 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 OWF47576.1 - 0.5 10.6 48.2 6.3 7.1 0.0 13.9 18 0 0 18 18 18 0 Leucine Rich repeat DUF745 PF05335.13 OWF47577.1 - 0.012 15.4 2.7 0.5 10.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) RBM1CTR PF08081.11 OWF47577.1 - 6.2 7.0 24.8 21 5.2 3.1 6.2 1 1 5 7 7 7 0 RBM1CTR (NUC064) family TRAPP PF04051.16 OWF47578.1 - 2.5e-32 111.6 0.0 3.1e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RWD PF05773.22 OWF47579.1 - 9.8e-24 83.9 5.7 2.1e-23 82.8 5.7 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 OWF47579.1 - 1.6e-05 25.3 7.1 1.6e-05 25.3 7.1 2.2 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 DUF445 PF04286.12 OWF47579.1 - 0.012 15.5 1.7 0.013 15.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RraB PF06877.11 OWF47579.1 - 0.039 14.7 7.1 0.18 12.5 1.2 2.6 1 1 1 2 2 2 0 Regulator of ribonuclease activity B HLH PF00010.26 OWF47580.1 - 4.4e-18 65.0 3.0 7.6e-18 64.2 3.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 OWF47581.1 - 9.4e-18 63.9 0.3 1.5e-17 63.3 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cas9-BH PF16593.5 OWF47581.1 - 0.06 13.1 1.6 0.19 11.4 1.6 1.8 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 HLH PF00010.26 OWF47582.1 - 4.9e-19 68.0 0.5 1.1e-18 66.9 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Coatomer_g_Cpla PF16381.5 OWF47582.1 - 0.036 14.2 0.7 1.5 9.0 0.0 2.6 2 1 1 3 3 3 0 Coatomer subunit gamma-1 C-terminal appendage platform HLH PF00010.26 OWF47583.1 - 9.7e-18 63.9 0.2 9.7e-18 63.9 0.2 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain zf-C2H2 PF00096.26 OWF47584.1 - 1.3e-16 60.1 34.9 6.7e-05 23.1 3.9 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47584.1 - 2.8e-13 49.5 30.5 0.0045 17.7 2.0 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF47584.1 - 9.2e-11 41.7 38.2 0.00027 21.2 2.0 6.0 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF47584.1 - 2e-09 37.5 17.5 0.038 14.3 0.0 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF47584.1 - 0.00019 21.7 18.0 0.14 12.6 0.9 4.5 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 OWF47584.1 - 0.0081 16.8 10.9 2.6 8.7 0.6 3.9 3 1 1 4 4 3 2 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 OWF47584.1 - 0.022 14.9 9.6 1.5 9.0 1.2 3.8 3 1 0 3 3 3 0 Zinc ribbon domain RNA_POL_M_15KD PF02150.16 OWF47584.1 - 0.28 11.1 4.1 38 4.3 0.2 3.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-C2H2_6 PF13912.6 OWF47584.1 - 0.37 10.9 28.9 2.6 8.1 5.4 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger BolA PF01722.18 OWF47584.1 - 0.4 11.0 3.9 36 4.7 3.4 2.9 1 1 0 1 1 1 0 BolA-like protein zf-C2H2_2 PF12756.7 OWF47584.1 - 0.56 10.6 20.8 1.7 9.0 1.6 4.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-ribbon_3 PF13248.6 OWF47584.1 - 0.72 9.4 3.3 4.4 6.9 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2HE PF16278.5 OWF47584.1 - 0.78 10.2 19.0 1.7 9.1 1.0 4.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Lar_restr_allev PF14354.6 OWF47584.1 - 1.2 9.6 5.7 33 5.0 0.4 3.4 2 1 0 3 3 3 0 Restriction alleviation protein Lar LIM PF00412.22 OWF47584.1 - 1.4 9.2 9.7 1.2 9.5 2.0 2.9 3 0 0 3 3 3 0 LIM domain DUF2256 PF10013.9 OWF47584.1 - 1.7 8.9 13.5 4.1 7.6 0.7 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 OWF47584.1 - 2.2 8.4 13.9 2.6 8.1 0.3 3.8 4 0 0 4 4 4 0 XPA protein N-terminal Baculo_IE-1 PF05290.11 OWF47584.1 - 2.6 8.0 7.2 35 4.3 2.7 3.2 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) TFIIS_C PF01096.18 OWF47584.1 - 5.7 6.9 10.2 56 3.7 0.1 4.1 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-Di19 PF05605.12 OWF47584.1 - 5.8 7.3 17.4 2.6 8.4 5.0 3.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 OWF47584.1 - 6.8 7.0 16.3 13 6.1 0.1 4.2 3 1 1 4 4 4 0 AN1-like Zinc finger zf-C2H2_9 PF16293.5 OWF47584.1 - 8.2 6.4 6.9 66 3.5 0.1 3.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) ORC3_N PF07034.11 OWF47585.1 - 8.4e-102 340.7 0.7 8.4e-102 340.7 0.7 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 OWF47585.1 - 6.1e-31 107.4 1.3 8.4e-29 100.4 0.1 2.9 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal FadA PF09403.10 OWF47585.1 - 0.0013 19.2 1.8 4.3 7.9 0.0 3.5 3 0 0 3 3 3 1 Adhesion protein FadA Med9 PF07544.13 OWF47585.1 - 0.0018 18.3 0.3 0.0079 16.3 0.3 2.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 OWF47585.1 - 0.81 9.9 6.1 1.9 8.7 1.7 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FliD_N PF02465.18 OWF47585.1 - 0.93 10.2 5.4 0.73 10.6 0.3 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DnaG_DnaB_bind PF08278.11 OWF47585.1 - 3.5 8.3 7.1 51 4.5 1.3 3.6 2 1 0 3 3 3 0 DNA primase DnaG DnaB-binding GMC_oxred_N PF00732.19 OWF47586.1 - 4.1e-76 256.2 0.0 5.1e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OWF47586.1 - 3.8e-43 147.4 0.0 8.6e-43 146.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF47586.1 - 2.3e-06 26.9 2.7 0.0055 15.8 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OWF47586.1 - 3.4e-05 24.0 0.6 9.9e-05 22.5 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OWF47586.1 - 0.00014 21.1 0.2 0.00029 20.0 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OWF47586.1 - 0.00032 20.0 0.1 0.0093 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF47586.1 - 0.0022 16.8 0.6 0.003 16.3 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OWF47586.1 - 0.0033 17.1 0.8 0.033 13.8 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF47586.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OWF47586.1 - 0.027 13.7 0.1 0.08 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OWF47586.1 - 0.036 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OWF47586.1 - 0.25 11.3 1.0 0.62 10.0 0.0 2.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding HLH PF00010.26 OWF47587.1 - 7.7e-13 48.2 0.2 2.6e-12 46.5 0.1 1.9 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain MAD PF05557.13 OWF47587.1 - 0.13 10.6 0.2 0.17 10.2 0.2 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Epiglycanin_TR PF05647.11 OWF47588.1 - 0.13 12.2 40.5 2 8.4 0.9 6.8 2 2 5 8 8 8 0 Tandem-repeating region of mucin, epiglycanin-like DUF2187 PF09953.9 OWF47588.1 - 2.4 8.2 4.2 8 6.5 0.3 3.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) Importin_rep_3 PF18806.1 OWF47589.1 - 0.085 12.9 0.0 7.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Importin 13 repeat Ank_4 PF13637.6 OWF47590.1 - 1.1e-11 45.0 0.1 6.7e-06 26.5 0.0 5.3 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF47590.1 - 3.4e-10 40.4 0.1 3.3e-06 27.6 0.0 4.0 3 2 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF47590.1 - 2.1e-06 27.9 0.5 0.2 12.0 0.0 5.5 4 1 2 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF47590.1 - 7.9e-05 22.8 0.3 20 6.2 0.0 6.1 6 0 0 6 6 5 0 Ankyrin repeat ResIII PF04851.15 OWF47590.1 - 0.0065 16.5 2.0 0.016 15.2 2.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF47590.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OWF47590.1 - 0.03 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OWF47590.1 - 0.048 13.1 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Ank PF00023.30 OWF47590.1 - 0.065 13.7 3.2 17 6.0 0.0 4.6 4 1 0 4 4 4 0 Ankyrin repeat NACHT PF05729.12 OWF47590.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Ploopntkinase2 PF18747.1 OWF47590.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 Sigma54_activat PF00158.26 OWF47590.1 - 0.088 12.5 0.2 0.26 11.0 0.2 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 OWF47590.1 - 0.11 12.5 1.7 0.52 10.3 0.5 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OWF47590.1 - 0.11 12.8 0.1 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 OWF47590.1 - 0.12 11.8 0.1 6.9 6.0 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Bac_rhamnosid_N PF08531.10 OWF47590.1 - 0.15 11.9 0.3 22 4.8 0.0 2.6 2 0 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain Anoctamin PF04547.12 OWF47591.1 - 2.1e-24 86.2 7.0 7.4e-15 54.7 2.8 2.1 1 1 1 2 2 2 2 Calcium-activated chloride channel Ras PF00071.22 OWF47591.1 - 2.4e-08 33.7 0.0 5.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Ras family T4_Rnl2_C PF18043.1 OWF47593.1 - 0.099 12.8 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal SKG6 PF08693.10 OWF47593.1 - 0.11 11.9 0.3 0.28 10.6 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PLDc PF00614.22 OWF47594.1 - 7.3e-18 63.9 1.5 5.2e-09 35.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 OWF47594.1 - 1.1e-16 60.8 7.2 1.4e-15 57.2 5.6 2.8 2 0 0 2 2 2 1 PX domain PLDc_2 PF13091.6 OWF47594.1 - 8.9e-16 58.0 1.0 1.4e-09 37.9 0.2 3.1 2 1 0 2 2 2 2 PLD-like domain Ank_2 PF12796.7 OWF47595.1 - 9.1e-21 74.3 3.5 2.5e-06 28.0 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF47595.1 - 2.9e-12 45.6 2.8 0.62 10.8 0.1 7.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OWF47595.1 - 2.9e-10 40.2 3.8 0.0034 17.7 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF47595.1 - 2.1e-09 37.7 0.0 0.00022 21.7 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) DED PF01335.21 OWF47595.1 - 0.00011 22.4 0.1 0.00011 22.4 0.1 2.8 3 0 0 3 3 3 1 Death effector domain Ank PF00023.30 OWF47595.1 - 0.0017 18.8 1.4 7 7.3 0.0 4.3 4 1 1 5 5 4 2 Ankyrin repeat AAA_22 PF13401.6 OWF47595.1 - 0.015 15.6 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OWF47595.1 - 0.016 14.5 0.0 0.038 13.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OWF47595.1 - 0.017 15.2 1.9 0.057 13.4 1.9 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OWF47595.1 - 0.023 14.1 0.1 0.099 12.1 0.0 2.0 1 1 1 2 2 2 0 PhoH-like protein DUF1128 PF06569.11 OWF47595.1 - 0.03 14.3 0.1 0.58 10.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) NACHT PF05729.12 OWF47595.1 - 0.093 12.6 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 OWF47595.1 - 0.094 12.4 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Anoctamin PF04547.12 OWF47596.1 - 3.7e-09 35.9 0.0 3.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ras PF00071.22 OWF47596.1 - 0.00034 20.3 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47596.1 - 0.00051 20.3 0.0 0.0019 18.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RRN3 PF05327.11 OWF47598.1 - 0.015 13.8 1.5 0.02 13.5 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.12 OWF47598.1 - 0.14 11.9 11.3 0.21 11.3 11.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 OWF47598.1 - 0.23 11.3 5.3 0.37 10.6 5.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM47 PF14642.6 OWF47599.1 - 1.8e-07 31.0 66.0 0.24 10.9 0.3 10.4 2 2 7 11 11 11 11 FAM47 family PKD_channel PF08016.12 OWF47600.1 - 1.5e-101 340.2 11.5 1.5e-101 340.2 11.5 2.3 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 OWF47600.1 - 1.1e-15 58.2 0.0 2.3e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 OWF47600.1 - 2e-05 24.0 28.5 2e-05 24.0 28.5 4.7 4 2 0 5 5 5 1 Ion transport protein GPS PF01825.21 OWF47600.1 - 0.00029 21.3 0.9 0.00088 19.8 0.9 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF3989 PF13150.6 OWF47600.1 - 6.6 6.5 7.1 0.34 10.7 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) zf-CCHC PF00098.23 OWF47601.1 - 0.003 17.5 2.0 0.0046 17.0 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle Citrus_P18 PF05520.11 OWF47602.1 - 0.035 13.8 0.8 2 8.1 0.0 2.7 1 1 2 3 3 3 0 Citrus tristeza virus P18 protein TGFb_propeptide PF00688.18 OWF47604.1 - 7e-24 84.9 0.1 1e-23 84.3 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 OWF47605.1 - 6.2e-34 117.1 0.4 1.2e-33 116.1 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain SR-25 PF10500.9 OWF47605.1 - 0.025 14.2 22.5 0.039 13.6 22.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LMBR1 PF04791.16 OWF47605.1 - 5.5 5.8 8.8 7.2 5.4 8.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cmc1 PF08583.10 OWF47606.1 - 3.9e-05 23.6 0.5 5.3e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like JMY PF15871.5 OWF47606.1 - 0.067 12.5 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein CHCH PF06747.13 OWF47606.1 - 0.08 13.1 2.9 0.11 12.6 2.9 1.3 1 0 0 1 1 1 0 CHCH domain SH3_1 PF00018.28 OWF47607.1 - 4.6e-23 80.6 0.2 1.4e-10 40.6 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 OWF47607.1 - 9.5e-21 73.7 0.2 4.3e-20 71.6 0.1 2.2 2 1 0 2 2 2 1 SH2 domain SH3_9 PF14604.6 OWF47607.1 - 4e-14 52.2 0.0 8.2e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OWF47607.1 - 1.4e-10 40.7 0.1 0.00086 18.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain DUF5093 PF17011.5 OWF47607.1 - 0.1 12.9 0.4 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) SH2 PF00017.24 OWF47608.1 - 9.9e-23 80.0 0.0 1.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 OWF47608.1 - 3.3e-20 71.7 0.4 9.5e-15 54.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OWF47608.1 - 1e-18 66.6 2.9 2.3e-15 55.9 0.2 3.2 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 OWF47608.1 - 4.2e-11 42.4 0.4 3.3e-10 39.5 0.1 2.5 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 OWF47609.1 - 6.2e-28 96.2 2.0 2.8e-16 58.8 0.2 2.8 3 0 0 3 3 3 2 SH3 domain SH2 PF00017.24 OWF47609.1 - 7e-24 83.7 0.0 1.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 OWF47609.1 - 1.6e-22 79.1 0.1 2.9e-15 55.9 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OWF47609.1 - 6.8e-17 60.9 0.0 4.1e-12 45.6 0.0 2.7 2 1 0 2 2 2 2 Variant SH3 domain DUF5093 PF17011.5 OWF47609.1 - 0.05 13.9 0.1 0.095 13.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5093) CDC24 PF06395.11 OWF47609.1 - 0.05 13.8 0.1 0.63 10.3 0.0 2.2 2 0 0 2 2 2 0 CDC24 Calponin Pyridoxal_deC PF00282.19 OWF47610.1 - 5.7e-11 41.7 0.0 1.2e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain GDC-P PF02347.16 OWF47610.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage system P-protein CNDH2_M PF16869.5 OWF47610.1 - 9.5 6.9 15.7 1.2 9.8 2.3 2.7 2 1 0 2 2 2 0 PF16858 MFS_1_like PF12832.7 OWF47611.1 - 1.7e-58 198.3 9.3 2.3e-58 197.9 9.3 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OWF47611.1 - 1.3e-08 34.2 41.0 6.7e-06 25.3 15.8 3.2 2 1 2 4 4 4 3 Major Facilitator Superfamily LacY_symp PF01306.19 OWF47611.1 - 0.00016 20.6 26.3 0.003 16.4 4.6 3.1 2 1 0 2 2 2 2 LacY proton/sugar symporter Cytochrom_B_C PF00032.17 OWF47611.1 - 1.3 9.3 7.9 0.13 12.6 1.6 2.6 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Dickkopf_N PF04706.12 OWF47612.1 - 0.0094 16.4 10.9 0.0095 16.4 1.1 2.4 2 0 0 2 2 2 2 Dickkopf N-terminal cysteine-rich region EB PF01683.18 OWF47612.1 - 5.9 7.3 13.7 1.4 9.2 1.8 2.9 2 1 0 2 2 2 0 EB module p450 PF00067.22 OWF47613.1 - 3.7e-100 335.9 0.0 4.2e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CAGE1 PF15066.6 OWF47614.1 - 0.0047 15.7 54.9 1.3 7.6 6.9 6.1 1 1 6 7 7 7 7 Cancer-associated gene protein 1 family OstA_2 PF13100.6 OWF47615.1 - 0.00035 20.2 0.7 29 4.2 0.0 6.0 1 1 4 6 6 6 2 OstA-like protein NQRA_SLBB PF11973.8 OWF47615.1 - 0.28 11.8 15.6 81 4.0 0.3 9.0 4 3 5 10 10 10 0 NQRA C-terminal domain OstA_2 PF13100.6 OWF47616.1 - 0.22 11.1 0.0 8.6 5.9 0.0 2.3 1 1 1 2 2 2 0 OstA-like protein TrkA_C PF02080.21 OWF47616.1 - 2.7 7.9 26.1 2.8 7.9 2.2 4.8 1 1 3 4 4 4 0 TrkA-C domain Peptidase_S24 PF00717.23 OWF47616.1 - 7.4 6.6 13.8 1.3e+02 2.6 2.9 4.7 1 1 1 2 2 2 0 Peptidase S24-like OstA_2 PF13100.6 OWF47617.1 - 0.0062 16.2 1.3 12 5.5 0.0 4.9 2 2 3 6 6 6 3 OstA-like protein DUF4469 PF14734.6 OWF47617.1 - 0.0078 16.4 6.2 43 4.4 0.0 6.7 3 2 4 7 7 7 1 Domain of unknown function (DUF4469) with IG-like fold Toast_rack_N PF17115.5 OWF47618.1 - 1.1 9.6 20.9 42 4.5 0.2 7.3 3 2 9 13 13 13 0 N-terminal domain of toast_rack, DUF2154 DUF963 PF06131.11 OWF47619.1 - 2.2e-06 27.0 34.8 0.15 11.5 0.5 9.5 4 2 10 15 15 15 9 Schizosaccharomyces pombe repeat of unknown function (DUF963) Chlam_OMP6 PF03504.13 OWF47619.1 - 0.1 12.9 29.9 30 5.0 0.2 8.1 1 1 8 10 10 10 0 Chlamydia cysteine-rich outer membrane protein 6 LVIVD PF08309.11 OWF47619.1 - 0.12 11.7 13.4 41 3.6 0.1 9.2 5 2 5 11 11 11 0 LVIVD repeat Myosin_TH1 PF06017.13 OWF47619.1 - 0.16 11.6 18.5 4.5 6.9 0.4 5.8 1 1 4 5 5 5 0 Unconventional myosin tail, actin- and lipid-binding APC_15aa PF05972.11 OWF47619.1 - 2.4 8.6 9.8 2.7e+02 2.1 0.1 7.1 7 0 0 7 7 7 0 APC 15 residue motif 7tm_1 PF00001.21 OWF47620.1 - 3.2e-11 43.1 27.7 4.2e-11 42.7 27.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF47620.1 - 8.3e-08 31.9 31.5 6.1e-06 25.7 31.5 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Pkinase PF00069.25 OWF47621.1 - 3.8e-08 33.0 0.0 4.4e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PBD PF00786.28 OWF47622.1 - 1.9e-24 85.8 0.1 3.8e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain ARS2 PF04959.13 OWF47623.1 - 0.99 9.7 2.7 1.4 9.3 2.7 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Scramblase PF03803.15 OWF47625.1 - 1.9e-21 76.4 1.4 2.4e-21 76.1 1.4 1.0 1 0 0 1 1 1 1 Scramblase Pro_CA PF00484.19 OWF47626.1 - 3.4e-35 121.6 0.0 5e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase HTH_28 PF13518.6 OWF47627.1 - 0.0014 18.7 0.1 0.48 10.6 0.0 2.9 1 1 2 3 3 3 2 Helix-turn-helix domain NUC205 PF08168.11 OWF47627.1 - 0.024 14.2 11.1 29 4.3 0.1 6.0 2 2 5 7 7 7 0 NUC205 domain Peptidase_MA_2 PF13485.6 OWF47627.1 - 0.025 14.3 0.2 2.7 7.6 0.1 2.3 1 1 1 2 2 2 0 Peptidase MA superfamily HTH_29 PF13551.6 OWF47627.1 - 0.22 11.6 0.5 8.2 6.5 0.1 2.6 1 1 2 3 3 3 0 Winged helix-turn helix DUF229 PF02995.17 OWF47628.1 - 3.5e-119 398.6 0.0 5.3e-119 398.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF47628.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Sulfatase Filamin PF00630.19 OWF47629.1 - 1.7e-71 237.6 9.7 2e-10 41.4 0.0 8.5 8 0 0 8 8 8 8 Filamin/ABP280 repeat CH PF00307.31 OWF47629.1 - 3.1e-41 140.0 0.3 1.1e-18 67.4 0.3 3.3 3 0 0 3 3 3 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OWF47629.1 - 9.1e-08 31.8 0.0 0.89 9.4 0.0 3.6 3 0 0 3 3 3 3 CAMSAP CH domain Invasin_D3 PF09134.10 OWF47629.1 - 0.0014 18.9 0.0 0.043 14.1 0.0 3.4 4 0 0 4 4 4 1 Invasin, domain 3 DUF5060 PF16586.5 OWF47629.1 - 0.0058 17.0 0.4 1 9.8 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF5060) SEA PF01390.20 OWF47630.1 - 5.2e-22 77.9 8.6 5.8e-08 32.8 0.0 4.8 4 1 1 5 5 5 4 SEA domain CCCAP PF15964.5 OWF47631.1 - 9.5e-11 40.7 76.3 9.5e-11 40.7 76.3 2.6 1 1 1 2 2 2 1 Centrosomal colon cancer autoantigen protein family DUF883 PF05957.13 OWF47631.1 - 0.0027 18.3 3.7 0.0027 18.3 3.7 7.8 3 2 5 8 8 8 1 Bacterial protein of unknown function (DUF883) Tropomyosin_1 PF12718.7 OWF47631.1 - 0.0036 17.5 4.4 0.0036 17.5 4.4 6.7 3 1 4 7 7 7 2 Tropomyosin like CENP-F_leu_zip PF10473.9 OWF47631.1 - 0.0041 17.2 9.2 0.0041 17.2 9.2 7.8 3 1 5 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Surfac_D-trimer PF09006.11 OWF47631.1 - 0.09 12.7 0.1 1.1 9.2 0.0 3.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation SH3_10 PF17902.1 OWF47631.1 - 2.4 8.3 6.5 0.55 10.4 0.8 3.0 3 0 0 3 3 3 0 SH3 domain DUF812 PF05667.11 OWF47632.1 - 3.4e-228 759.4 29.6 3.4e-228 759.4 29.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF812) Latarcin PF10279.9 OWF47632.1 - 0.00066 20.0 1.8 0.086 13.3 1.1 4.1 2 1 0 2 2 2 1 Latarcin precursor HALZ PF02183.18 OWF47632.1 - 0.088 13.0 2.1 1.2 9.4 0.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Hemerythrin PF01814.23 OWF47632.1 - 0.17 12.5 0.1 0.17 12.5 0.1 3.5 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain Flu_M1_C PF08289.11 OWF47632.1 - 0.52 10.6 7.4 0.19 11.9 0.6 3.7 2 2 2 4 4 4 0 Influenza Matrix protein (M1) C-terminal domain NMD3 PF04981.13 OWF47632.1 - 0.69 9.3 8.2 0.088 12.3 2.0 2.7 3 0 0 3 3 3 0 NMD3 family Rsd_AlgQ PF04353.13 OWF47632.1 - 6 6.8 14.6 0.3 11.0 3.8 3.9 3 2 1 4 4 4 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Rep_4 PF05797.11 OWF47633.1 - 0.0031 16.7 0.7 0.0031 16.7 0.7 1.9 1 1 1 2 2 2 1 Yeast trans-acting factor (REP1/REP2) GTP_EFTU PF00009.27 OWF47634.1 - 2.6e-53 180.5 0.1 3.9e-53 179.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OWF47634.1 - 4.4e-41 139.4 1.9 9e-41 138.4 1.9 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OWF47634.1 - 2.9e-22 78.5 0.0 9.1e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 OWF47634.1 - 2.9e-05 23.9 0.0 6.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 OWF47634.1 - 2.9e-05 24.4 0.0 6.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 OWF47634.1 - 6.6e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 OWF47634.1 - 0.0056 16.7 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 OWF47634.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 OWF47634.1 - 0.067 13.4 0.1 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF47635.1 - 2.4e-55 186.5 0.0 2.9e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47635.1 - 1.1e-29 103.0 0.0 1.7e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF47635.1 - 1.3e-10 41.0 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF47635.1 - 6.6e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF47635.1 - 0.00027 20.9 0.1 0.0024 17.8 0.1 2.0 1 1 1 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OWF47635.1 - 0.00039 19.8 0.0 0.00068 19.1 0.0 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OWF47635.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OWF47635.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OWF47635.1 - 0.018 15.5 0.0 0.025 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 OWF47635.1 - 0.026 14.1 0.0 0.24 10.9 0.0 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OWF47635.1 - 0.041 14.2 0.0 0.33 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OWF47635.1 - 0.071 12.3 0.6 4.1 6.5 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit ATPase_2 PF01637.18 OWF47635.1 - 0.1 12.5 0.0 0.44 10.4 0.0 1.9 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OWF47635.1 - 0.1 12.3 0.1 0.26 11.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OWF47635.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OWF47635.1 - 0.13 11.5 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Septin Exo_endo_phos PF03372.23 OWF47637.1 - 1.3e-18 67.4 0.0 4.5e-18 65.6 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OWF47637.1 - 0.0027 17.6 0.0 0.0071 16.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Cadherin PF00028.17 OWF47638.1 - 2.2e-95 313.3 21.6 3.8e-19 68.9 0.2 7.3 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 OWF47638.1 - 8.7e-16 57.5 1.5 1.4e-09 37.6 0.1 6.6 6 2 0 6 6 6 1 Cadherin-like Cadherin_3 PF16184.5 OWF47638.1 - 3.5e-06 27.0 14.8 1.3 9.0 0.1 6.5 6 0 0 6 6 6 4 Cadherin-like Cadherin_pro PF08758.11 OWF47638.1 - 0.00098 19.2 0.3 9.2 6.5 0.0 3.8 3 0 0 3 3 3 1 Cadherin prodomain like TMEM154 PF15102.6 OWF47638.1 - 0.051 13.5 0.3 0.2 11.6 0.3 2.0 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OWF47638.1 - 0.3 10.9 2.3 0.65 9.8 2.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin PF00028.17 OWF47639.1 - 1.9e-102 336.0 17.6 3.5e-22 78.7 0.9 7.7 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 OWF47639.1 - 2.1e-17 62.7 0.1 6e-13 48.4 0.2 4.7 4 1 0 4 4 4 1 Cadherin-like Cadherin_3 PF16184.5 OWF47639.1 - 4.9e-08 33.0 15.9 1 9.4 0.1 7.6 7 0 0 7 7 7 4 Cadherin-like Shisa PF13908.6 OWF47639.1 - 0.0077 16.5 0.9 0.027 14.7 0.9 1.9 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF47639.1 - 0.088 13.7 2.1 0.12 13.3 0.4 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.11 OWF47639.1 - 0.12 12.2 0.9 0.34 10.8 0.9 1.7 1 0 0 1 1 1 0 TMEM9 TRP PF06011.12 OWF47639.1 - 0.25 10.0 2.5 0.39 9.4 2.5 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Rotamase PF00639.21 OWF47639.1 - 2.4 9.2 6.0 6.2 7.9 0.9 3.4 3 0 0 3 3 3 0 PPIC-type PPIASE domain DUF4834 PF16118.5 OWF47639.1 - 3.9 8.5 9.7 0.097 13.6 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) HIP1_clath_bdg PF16515.5 OWF47641.1 - 0.0039 17.8 9.0 0.0039 17.8 9.0 3.2 2 1 1 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 HALZ PF02183.18 OWF47641.1 - 0.0063 16.7 6.9 0.0063 16.7 6.9 3.0 3 0 0 3 3 3 1 Homeobox associated leucine zipper WXG100 PF06013.12 OWF47641.1 - 0.17 12.1 8.0 4.1 7.7 3.1 2.8 2 1 0 2 2 2 0 Proteins of 100 residues with WXG GIT_CC PF16559.5 OWF47641.1 - 0.4 10.6 14.5 0.27 11.1 2.4 3.9 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fibin PF15819.5 OWF47641.1 - 0.88 9.3 13.1 1.9 8.2 1.7 2.3 2 0 0 2 2 2 0 Fin bud initiation factor homologue Spc7 PF08317.11 OWF47641.1 - 2.6 6.9 26.2 0.25 10.2 8.7 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Rootletin PF15035.6 OWF47641.1 - 3 7.8 26.7 90 3.0 26.9 2.8 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 OWF47641.1 - 3.8 8.0 27.3 0.098 13.1 9.4 3.6 1 1 2 3 3 3 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 OWF47641.1 - 4.1 7.7 25.1 0.12 12.6 10.1 3.2 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding NEMO PF11577.8 OWF47641.1 - 4.3 7.4 23.5 0.2 11.7 8.9 3.3 2 1 2 4 4 4 0 NF-kappa-B essential modulator NEMO APG6_N PF17675.1 OWF47641.1 - 6.1 7.4 35.3 0.85 10.2 19.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Nsp1_C PF05064.13 OWF47641.1 - 9.1 6.1 18.1 3.4 7.5 8.1 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region HSP70 PF00012.20 OWF47642.1 - 6.5e-13 47.7 0.0 4.6e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein F-box-like PF12937.7 OWF47643.1 - 4.1e-06 26.6 0.3 1.3e-05 25.0 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF47643.1 - 0.00022 21.0 0.3 0.00051 19.9 0.3 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 OWF47643.1 - 0.02 14.2 3.0 0.097 12.0 0.1 2.3 1 1 0 2 2 2 0 WD40-like domain TMEM169 PF15052.6 OWF47643.1 - 0.055 13.6 0.5 0.63 10.2 0.4 2.4 2 0 0 2 2 2 0 TMEM169 protein family Kelch_1 PF01344.25 OWF47644.1 - 8e-42 140.6 1.6 4.6e-13 48.5 0.1 4.7 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OWF47644.1 - 3.2e-33 112.9 0.4 3.6e-08 33.4 0.2 5.0 3 2 2 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OWF47644.1 - 2.1e-24 84.5 0.1 1.1e-08 34.7 0.1 5.9 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 OWF47644.1 - 2.7e-24 85.5 0.5 6.2e-23 81.1 0.6 2.5 1 1 1 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 OWF47644.1 - 5.9e-22 77.4 0.0 5.7e-07 29.4 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain BACK PF07707.15 OWF47644.1 - 7.7e-18 64.5 0.1 3.4e-17 62.4 0.0 2.1 1 1 1 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 OWF47644.1 - 2.5e-17 62.4 1.9 3.4e-05 23.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OWF47644.1 - 2.6e-16 59.5 0.2 5.1e-06 26.6 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Sec34 PF04136.15 OWF47644.1 - 0.014 15.3 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Sec34-like family DUF3342 PF11822.8 OWF47644.1 - 0.018 15.2 0.1 0.046 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 OWF47644.1 - 0.16 12.5 0.1 0.97 10.0 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain SNF PF00209.18 OWF47645.1 - 3.2e-215 715.7 40.1 7.7e-215 714.5 40.1 1.5 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF47646.1 - 2.6e-215 716.1 39.3 3.4e-215 715.7 39.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family T-box PF00907.22 OWF47647.1 - 1e-54 185.6 0.0 1.5e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 T-box T-box PF00907.22 OWF47649.1 - 1.1e-39 136.6 0.0 1.4e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 T-box SeqA_N PF17206.3 OWF47649.1 - 0.097 12.0 0.1 18 4.8 0.0 3.1 3 0 0 3 3 3 0 SeqA protein N-terminal domain T-box PF00907.22 OWF47650.1 - 1.1e-11 45.3 0.0 1.1e-11 45.3 0.0 1.0 1 0 0 1 1 1 1 T-box Scm3 PF10384.9 OWF47651.1 - 0.0025 17.5 0.2 0.0069 16.1 0.2 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Macro PF01661.21 OWF47652.1 - 6.3e-33 113.3 0.0 2.4e-18 66.3 0.0 2.5 2 0 0 2 2 2 2 Macro domain PARP PF00644.20 OWF47652.1 - 1.4e-12 47.7 0.0 3.7e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RBR PF17208.3 OWF47652.1 - 1.4 9.7 5.3 4.9 7.9 5.3 1.9 1 0 0 1 1 1 0 RNA binding Region Complex1_LYR PF05347.15 OWF47653.1 - 4e-11 42.8 0.0 7.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF247 PF03140.15 OWF47653.1 - 0.024 13.9 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Plant protein of unknown function HEPN PF05168.14 OWF47653.1 - 0.22 11.7 1.1 14 5.9 0.1 2.1 1 1 1 2 2 2 0 HEPN domain TMEM232 PF15877.5 OWF47654.1 - 3.3e-112 375.8 0.0 4.1e-83 279.9 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein family 232 Melibiase_2 PF16499.5 OWF47655.1 - 1.1e-127 425.1 2.6 1.3e-127 424.8 2.6 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 OWF47655.1 - 7.3e-06 25.2 0.0 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 OWF47655.1 - 4.8e-05 23.5 0.0 0.00012 22.3 0.0 1.7 1 1 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 OWF47655.1 - 0.00067 19.7 0.0 0.0025 17.9 0.0 2.0 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2 PF16499.5 OWF47656.1 - 3.5e-138 459.5 2.1 4.1e-138 459.3 2.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 OWF47656.1 - 2.4e-14 53.3 0.0 4.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 OWF47656.1 - 2.3e-06 27.6 0.0 6.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OWF47656.1 - 1.4e-05 24.2 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase N2227 PF07942.12 OWF47657.1 - 0.048 12.8 0.7 3.3 6.8 0.1 2.8 1 1 1 2 2 2 0 N2227-like protein SEEK1 PF15357.6 OWF47657.1 - 1.2 9.2 5.0 13 5.9 0.8 3.0 1 1 1 2 2 2 0 Psoriasis susceptibility 1 candidate 1 COesterase PF00135.28 OWF47658.1 - 2.7e-150 501.7 0.0 3.1e-150 501.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47658.1 - 6e-10 39.3 0.1 1.1e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold C1q PF00386.21 OWF47659.1 - 2.3e-17 63.4 0.0 4.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 C1q domain PCB_OB PF17092.5 OWF47659.1 - 0.08 13.7 0.6 10 6.9 0.1 3.0 3 0 0 3 3 3 0 Penicillin-binding protein OB-like domain CCDC-167 PF15188.6 OWF47659.1 - 0.66 10.4 4.5 0.21 12.0 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ABC_tran_CTD PF16326.5 OWF47659.1 - 0.84 9.9 3.6 1.7 8.9 2.9 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain C1q PF00386.21 OWF47660.1 - 4e-18 65.8 0.1 8.1e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 C1q domain CCDC144C PF14915.6 OWF47660.1 - 0.0012 18.1 0.1 0.0012 18.1 0.1 1.4 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region DHR10 PF18595.1 OWF47660.1 - 0.0039 17.2 1.2 0.0039 17.2 1.2 1.5 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain Lipocalin_3 PF12702.7 OWF47660.1 - 0.12 12.5 0.7 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 Lipocalin-like C1q PF00386.21 OWF47661.1 - 1.9e-16 60.5 0.0 3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 C1q domain DUF3552 PF12072.8 OWF47661.1 - 0.0089 15.5 0.4 0.014 14.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF641 PF04859.12 OWF47661.1 - 0.02 15.2 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2730 PF10805.8 OWF47661.1 - 0.29 11.2 1.7 2.6 8.2 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Xan_ur_permease PF00860.20 OWF47663.1 - 5.7e-72 242.6 27.8 7.8e-72 242.1 27.8 1.2 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 OWF47664.1 - 2.1e-69 234.1 30.1 2.8e-69 233.7 30.1 1.1 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 OWF47665.1 - 3.9e-72 243.1 28.4 5.6e-72 242.6 28.4 1.2 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 OWF47666.1 - 1.5e-71 241.2 30.2 2.4e-71 240.5 30.2 1.3 1 0 0 1 1 1 1 Permease family EIAV_GP90 PF00971.18 OWF47666.1 - 0.32 9.6 0.9 0.54 8.9 0.9 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 MFS_MOT1 PF16983.5 OWF47666.1 - 7.2 7.1 21.6 0.17 12.3 3.0 3.8 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily LRR_8 PF13855.6 OWF47667.1 - 1.3e-99 325.9 94.3 1.9e-14 53.2 4.0 13.3 10 3 5 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 OWF47667.1 - 4e-56 186.0 109.1 1.3e-06 28.6 0.3 14.7 13 1 1 14 14 14 14 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF47667.1 - 8.9e-29 100.0 36.3 3.6e-07 30.2 0.0 7.3 2 1 5 8 8 8 8 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF47667.1 - 5.2e-20 68.9 85.6 0.24 12.1 0.6 22.9 27 0 0 27 27 27 8 Leucine Rich Repeat LRR_9 PF14580.6 OWF47667.1 - 4.3e-18 65.4 42.8 0.00052 19.6 2.5 7.4 2 1 5 8 8 8 6 Leucine-rich repeat LRR_6 PF13516.6 OWF47667.1 - 2.2e-06 27.3 97.8 0.34 11.1 0.8 20.8 22 0 0 22 22 22 6 Leucine Rich repeat TIR_2 PF13676.6 OWF47667.1 - 2.5e-06 28.1 0.1 8.9e-06 26.3 0.1 2.0 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF47667.1 - 2.3e-05 24.3 0.1 4.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain Antistasin PF02822.14 OWF47668.1 - 7.3e-06 26.5 4.8 7.3e-06 26.5 4.8 4.6 3 2 1 4 4 4 4 Antistasin family Tir_receptor_C PF07489.11 OWF47668.1 - 0.0083 16.1 1.4 0.011 15.7 1.4 1.2 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) C-terminus Antistasin PF02822.14 OWF47669.1 - 1.3e-06 28.9 57.9 0.04 14.6 8.7 4.3 4 0 0 4 4 4 4 Antistasin family Antistasin PF02822.14 OWF47670.1 - 5.8e-12 46.0 46.5 5.3e-07 30.2 10.9 4.5 4 0 0 4 4 4 2 Antistasin family DUF832 PF05734.11 OWF47670.1 - 0.23 10.9 1.0 0.34 10.4 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus protein of unknown function (DUF832) F5_F8_type_C PF00754.25 OWF47671.1 - 1.7e-22 79.9 1.8 3.9e-22 78.7 1.8 1.6 1 0 0 1 1 1 1 F5/8 type C domain Gal_Lectin PF02140.18 OWF47671.1 - 8e-17 61.4 2.8 8e-17 61.4 2.8 2.7 3 0 0 3 3 3 1 Galactose binding lectin domain Lectin_C PF00059.21 OWF47671.1 - 1.1e-14 55.1 0.1 4.1e-14 53.2 0.1 2.1 1 0 0 1 1 1 1 Lectin C-type domain CBM_14 PF01607.24 OWF47671.1 - 0.0024 18.0 6.8 0.0024 18.0 6.8 4.7 6 0 0 6 6 6 1 Chitin binding Peritrophin-A domain Hormone_recep PF00104.30 OWF47672.1 - 2.6e-31 108.8 0.1 6.4e-31 107.5 0.1 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF47672.1 - 2.2e-28 98.5 16.3 3.5e-28 97.9 16.3 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SID-1_RNA_chan PF13965.6 OWF47673.1 - 2.3e-238 792.5 15.6 3.5e-238 792.0 15.6 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Ceramidase PF05875.12 OWF47673.1 - 0.003 17.0 21.9 0.58 9.5 21.9 2.5 1 1 0 1 1 1 1 Ceramidase YbjM PF11045.8 OWF47673.1 - 0.38 10.9 9.9 0.13 12.4 3.0 2.9 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae 60KD_IMP PF02096.20 OWF47673.1 - 0.61 10.0 9.3 1.7 8.5 2.5 2.6 2 0 0 2 2 2 0 60Kd inner membrane protein DUF2157 PF09925.9 OWF47673.1 - 1.1 9.0 9.0 0.65 9.8 3.2 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SID-1_RNA_chan PF13965.6 OWF47674.1 - 5.1e-173 576.8 41.5 1e-129 433.8 29.6 2.2 1 1 1 2 2 2 2 dsRNA-gated channel SID-1 CstA_5TM PF13722.6 OWF47674.1 - 0.008 16.5 0.7 0.008 16.5 0.7 2.5 3 0 0 3 3 3 1 5TM C-terminal transporter carbon starvation CstA DUF2070 PF09843.9 OWF47674.1 - 2 6.6 20.3 2.8 6.1 14.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2070) p450 PF00067.22 OWF47675.1 - 3.5e-111 372.2 0.0 4e-111 372.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF47676.1 - 8.3e-115 384.2 0.0 9.4e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1495 PF07381.11 OWF47676.1 - 0.14 12.0 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) PXA PF02194.15 OWF47677.1 - 7.4e-32 110.8 0.3 7.4e-32 110.8 0.3 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 OWF47677.1 - 8.6e-25 87.5 0.0 7e-24 84.6 0.0 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal RGS PF00615.19 OWF47677.1 - 1.9e-19 70.1 0.6 1.9e-19 70.1 0.6 2.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain PX PF00787.24 OWF47677.1 - 3.1e-08 33.6 0.2 1.8e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 PX domain Isy1 PF06246.12 OWF47677.1 - 2.6e-06 27.2 6.7 1.9e-05 24.4 0.1 2.4 2 0 0 2 2 2 1 Isy1-like splicing family Fmp27_WPPW PF10359.9 OWF47677.1 - 0.0013 17.7 2.7 0.0027 16.7 2.7 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF4898 PF16239.5 OWF47677.1 - 0.056 13.4 1.4 0.37 10.8 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4898) Jnk-SapK_ap_N PF09744.9 OWF47677.1 - 0.069 13.4 9.2 0.25 11.5 9.2 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 OWF47677.1 - 0.075 12.1 0.7 0.14 11.2 0.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myosin_tail_1 PF01576.19 OWF47677.1 - 0.12 10.1 9.6 0.1 10.4 7.8 1.6 2 0 0 2 2 2 0 Myosin tail Ank_4 PF13637.6 OWF47678.1 - 9.6e-27 93.0 2.3 2.1e-11 44.1 0.1 4.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF47678.1 - 3.8e-25 88.3 0.2 3.9e-13 49.8 0.1 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF47678.1 - 1.3e-17 63.4 0.5 0.00077 19.8 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OWF47678.1 - 5.8e-15 53.9 0.2 0.05 14.2 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF47678.1 - 1.2e-11 44.5 0.7 0.0064 16.8 0.0 4.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Cornifin PF02389.15 OWF47679.1 - 8.2e-13 48.7 93.6 0.00047 20.4 25.5 4.1 1 1 3 4 4 4 4 Cornifin (SPRR) family Forkhead_N PF08430.12 OWF47679.1 - 2.9 8.5 46.9 55 4.4 6.7 5.1 1 1 2 3 3 3 0 Forkhead N-terminal region UQ_con PF00179.26 OWF47680.1 - 1.3e-53 180.5 0.1 1.5e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF47680.1 - 0.0019 18.4 0.2 0.0037 17.5 0.1 1.7 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 OWF47680.1 - 0.0063 16.2 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B bZIP_2 PF07716.15 OWF47680.1 - 0.012 15.7 1.2 0.02 15.0 1.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper UEV PF05743.13 OWF47680.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF5487 PF17589.2 OWF47680.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5487) Peptidase_C78 PF07910.13 OWF47681.1 - 5.5e-49 166.5 0.0 9.9e-49 165.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 ODR4-like PF14778.6 OWF47681.1 - 0.12 11.3 0.1 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 Olfactory receptor 4-like ADP_ribosyl_GH PF03747.14 OWF47682.1 - 1.3e-46 159.7 0.0 1.5e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF4749 PF15936.5 OWF47684.1 - 8e-07 30.1 0.0 8e-07 30.1 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 OWF47684.1 - 4.9e-06 26.3 0.2 9.7e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OWF47684.1 - 1.9e-05 24.9 0.0 3.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Xan_ur_permease PF00860.20 OWF47685.1 - 4e-89 299.0 22.8 6.8e-89 298.3 22.8 1.3 1 0 0 1 1 1 1 Permease family MFS_1 PF07690.16 OWF47686.1 - 0.00012 21.1 1.3 0.00014 21.0 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF47686.1 - 0.00064 18.7 1.7 0.001 18.0 1.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2428 PF10350.9 OWF47686.1 - 0.0071 15.6 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) Cons_hypoth698 PF03601.14 OWF47686.1 - 0.031 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MFS_1 PF07690.16 OWF47687.1 - 3.9e-10 39.2 14.2 3.9e-10 39.2 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sensor_TM1 PF13755.6 OWF47687.1 - 0.039 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Helicase_C PF00271.31 OWF47688.1 - 2.8e-14 53.4 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PyrI_C PF02748.15 OWF47689.1 - 0.068 13.1 0.8 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4520 PF15016.6 OWF47689.1 - 0.084 13.0 0.1 0.16 12.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4520) CFTR_R PF14396.6 OWF47691.1 - 0.091 12.3 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Glyco_transf_10 PF00852.19 OWF47692.1 - 3.3e-44 150.7 1.9 3.7e-44 150.6 1.9 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Nudix_N_2 PF14803.6 OWF47692.1 - 0.16 11.9 3.2 0.83 9.6 0.5 2.8 3 0 0 3 3 3 0 Nudix N-terminal DUF2345 PF10106.9 OWF47693.1 - 8.5e-06 25.7 2.1 1.1 9.1 0.1 4.1 1 1 5 6 6 6 4 Uncharacterized protein conserved in bacteria (DUF2345) DUF826 PF05696.11 OWF47693.1 - 0.87 9.7 16.1 1e+02 3.1 0.1 6.5 3 3 4 7 7 7 0 Protein of unknown function (DUF826) EF-hand_5 PF13202.6 OWF47693.1 - 5.4 6.7 12.2 2.3e+02 1.6 0.0 6.2 6 0 0 6 6 6 0 EF hand Chordopox_G3 PF06129.12 OWF47693.1 - 9 7.1 12.1 36 5.1 3.2 3.3 1 1 2 3 3 3 0 Chordopoxvirus G3 protein HLH PF00010.26 OWF47694.1 - 4e-15 55.5 0.9 7.4e-15 54.6 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Atg31 PF09795.9 OWF47695.1 - 3.3e-11 43.4 4.7 1.5 8.8 0.0 8.4 1 1 6 7 7 7 5 Autophagy-related protein 31 LAP2alpha PF11560.8 OWF47695.1 - 2.1e-05 24.1 0.9 22 4.4 0.0 6.5 1 1 4 6 6 6 3 Lamina-associated polypeptide 2 alpha Fibritin_C PF07921.12 OWF47695.1 - 2.7 8.2 8.5 53 4.0 0.0 5.8 6 2 2 8 8 8 0 Fibritin C-terminal region Glyco_hydro_26 PF02156.15 OWF47696.1 - 2.3e-42 145.5 3.7 4.2e-42 144.7 3.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 Kinesin PF00225.23 OWF47697.1 - 1.1e-107 359.8 0.6 1.1e-107 359.8 0.6 2.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF47697.1 - 5.7e-25 88.0 0.6 2.7e-24 85.8 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding RNA_pol_Rpb6 PF01192.22 OWF47697.1 - 0.026 14.5 2.5 4.7 7.2 0.0 3.8 4 0 0 4 4 4 0 RNA polymerase Rpb6 DUF3584 PF12128.8 OWF47697.1 - 0.54 7.7 90.2 0.41 8.1 50.1 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ASH PF15780.5 OWF47698.1 - 0.17 12.1 5.9 4.1 7.7 0.1 3.8 1 1 3 5 5 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Glyco_hydro_35 PF01301.19 OWF47699.1 - 1.2e-116 389.8 0.1 1.5e-116 389.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OWF47699.1 - 8.7e-14 51.6 0.1 4.9e-12 45.9 0.1 2.2 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 OWF47700.1 - 2.6e-109 365.7 0.0 3.2e-109 365.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OWF47700.1 - 9.9e-13 48.2 0.5 5.2e-11 42.5 0.5 2.1 1 1 0 1 1 1 1 Beta-galactosidase adh_short PF00106.25 OWF47701.1 - 3.4e-29 101.7 0.0 4.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF47701.1 - 1.1e-12 48.1 0.0 1.9e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF47701.1 - 0.00041 20.3 0.0 0.00079 19.4 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OWF47702.1 - 2.5e-26 92.4 0.0 4.5e-26 91.5 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF47702.1 - 2.2e-14 53.6 0.0 3.6e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF47702.1 - 0.0013 18.6 0.1 0.0043 17.0 0.0 1.8 2 1 0 2 2 2 1 KR domain Sigma54_activat PF00158.26 OWF47702.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PALP PF00291.25 OWF47703.1 - 7.1e-24 84.7 0.0 8.6e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 OWF47704.1 - 3.2e-18 65.8 39.0 3.4e-12 46.0 8.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 OWF47704.1 - 0.00011 21.6 11.5 0.0063 15.9 6.1 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Stevor PF17410.2 OWF47704.1 - 0.23 10.9 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame 7TM_GPCR_Srsx PF10320.9 OWF47704.1 - 4.1 6.7 9.7 0.79 9.1 0.2 2.8 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx MFS_1 PF07690.16 OWF47705.1 - 8.4e-08 31.5 53.6 1.5e-05 24.1 27.3 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily MotB_plug PF13677.6 OWF47705.1 - 5.4 6.7 6.3 0.3 10.7 0.6 1.9 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB MFS_1 PF07690.16 OWF47706.1 - 1.4e-08 34.0 14.6 1.4e-08 34.0 14.6 3.3 2 2 2 4 4 4 2 Major Facilitator Superfamily DUF3272 PF11676.8 OWF47706.1 - 6.3 7.1 8.6 59 4.0 6.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3272) Integrin_alpha2 PF08441.12 OWF47708.1 - 7.5e-43 147.1 0.2 1.2e-42 146.4 0.2 1.3 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 OWF47708.1 - 1.8e-12 47.2 11.2 1.1e-05 25.4 0.9 4.1 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.6 OWF47708.1 - 1.1e-05 25.9 9.9 8.3e-05 23.1 4.6 3.7 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 OWF47708.1 - 0.01 15.8 1.5 0.027 14.4 1.5 1.8 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region TcdB_toxin_midN PF12256.8 OWF47708.1 - 0.028 13.8 0.4 0.076 12.4 0.1 1.8 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region DUF4797 PF16051.5 OWF47708.1 - 0.076 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) RRM PF10378.9 OWF47708.1 - 0.15 11.8 0.8 29 4.5 0.0 3.1 3 0 0 3 3 3 0 Putative RRM domain FG-GAP_2 PF14312.6 OWF47708.1 - 1.4 9.3 3.1 9.9 6.5 0.3 3.7 4 0 0 4 4 4 0 FG-GAP repeat Pkinase PF00069.25 OWF47709.1 - 2.5e-36 125.4 0.0 3.5e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF47709.1 - 5.5e-16 58.6 0.0 8.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF47709.1 - 0.0084 15.5 0.0 0.3 10.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OWF47709.1 - 0.035 14.0 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OWF47709.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase VWC PF00093.18 OWF47710.1 - 3.2e-34 117.0 93.8 0.00012 22.3 2.6 13.1 13 0 0 13 13 13 12 von Willebrand factor type C domain Pacifastin_I PF05375.13 OWF47710.1 - 1.7e-33 114.0 106.2 4.7e-07 29.4 5.0 14.3 13 0 0 13 13 13 11 Pacifastin inhibitor (LCMII) TILa PF12714.7 OWF47710.1 - 2.3e-32 110.7 102.9 0.00094 19.1 4.7 13.1 13 0 0 13 13 13 12 TILa domain Minor_capsid_1 PF10665.9 OWF47710.1 - 1.2e-05 25.5 12.7 35 4.7 0.0 7.7 2 1 6 8 8 8 0 Minor capsid protein CFC PF09443.10 OWF47710.1 - 0.00026 20.8 86.0 1.7 8.5 3.0 13.2 13 0 0 13 13 13 8 Cripto_Frl-1_Cryptic (CFC) DUF1496 PF07383.12 OWF47710.1 - 0.00036 20.0 30.9 19 4.9 0.1 9.4 9 0 0 9 9 9 3 Protein of unknown function (DUF1496) ProRS-C_2 PF09181.10 OWF47710.1 - 0.00058 19.9 11.3 1.4e+02 2.6 0.0 8.0 9 0 0 9 9 9 0 Prolyl-tRNA synthetase, C-terminal Glyco_hydro_11 PF00457.17 OWF47710.1 - 0.15 11.6 4.8 41 3.7 0.0 4.3 2 1 6 8 8 8 0 Glycosyl hydrolases family 11 Rif1_N PF12231.8 OWF47711.1 - 1.1e-50 172.7 12.8 1.1e-50 172.7 12.8 2.0 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Integrin_alpha2 PF08441.12 OWF47712.1 - 5e-34 118.0 4.6 9e-34 117.1 4.6 1.4 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 OWF47712.1 - 2.3e-06 27.6 1.6 2.3e-06 27.6 1.6 3.8 4 0 0 4 4 4 1 FG-GAP repeat FG-GAP_2 PF14312.6 OWF47712.1 - 8.2e-05 22.8 2.3 0.94 9.8 0.5 3.9 3 0 0 3 3 3 2 FG-GAP repeat Integrin_alpha PF00357.20 OWF47712.1 - 0.00067 19.5 2.8 0.0017 18.2 2.8 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region VCBS PF13517.6 OWF47712.1 - 0.022 15.3 0.3 0.29 11.8 0.1 3.0 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HTH_Tnp_4 PF13613.6 OWF47713.1 - 1.1e-07 31.5 0.1 2.1e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Na_Ca_ex PF01699.24 OWF47714.1 - 1.2e-52 177.9 45.1 6.3e-28 97.6 16.2 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Kei1 PF08552.11 OWF47714.1 - 0.015 15.1 2.3 0.052 13.4 2.3 1.9 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4131 PF13567.6 OWF47714.1 - 6.2 6.5 7.5 67 3.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Integrin_alpha2 PF08441.12 OWF47715.1 - 1.1e-38 133.3 0.4 2e-38 132.5 0.0 1.6 1 1 1 2 2 2 1 Integrin alpha FG-GAP PF01839.23 OWF47715.1 - 7.5e-16 58.0 8.3 7e-08 32.5 2.3 4.5 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.6 OWF47715.1 - 6.5e-09 36.3 11.3 8.9e-06 26.2 2.4 3.1 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 OWF47715.1 - 3.9e-07 30.2 5.7 0.74 10.1 0.0 4.8 5 0 0 5 5 5 3 FG-GAP repeat HisK_sensor PF18698.1 OWF47715.1 - 0.076 13.4 0.0 26 5.2 0.0 3.2 3 0 0 3 3 3 0 Histidine kinase sensor domain PRY PF13765.6 OWF47715.1 - 0.099 12.3 0.2 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 SPRY-associated domain OB_NTP_bind PF07717.16 OWF47716.1 - 2.2e-25 88.8 0.0 4.9e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OWF47716.1 - 3.2e-24 85.3 0.4 3.2e-24 85.3 0.4 3.7 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OWF47716.1 - 2.6e-13 50.3 0.0 1.8e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.23 OWF47716.1 - 9e-13 48.4 0.6 2.9e-12 46.7 0.6 2.0 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 OWF47716.1 - 3.2e-06 27.0 0.2 8.4e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF47716.1 - 0.00015 22.0 0.3 0.001 19.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OWF47716.1 - 0.00073 19.9 0.1 0.0018 18.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OWF47716.1 - 0.0027 16.8 0.2 0.0073 15.4 0.2 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 OWF47716.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OWF47716.1 - 0.038 14.5 0.0 0.24 11.9 0.0 2.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OWF47716.1 - 0.054 13.9 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 OWF47716.1 - 0.1 12.0 0.1 0.29 10.6 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 OWF47716.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain 7tm_2 PF00002.24 OWF47717.1 - 1e-47 162.5 13.8 1.4e-47 162.0 13.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF47717.1 - 3.2e-12 46.5 2.9 8e-12 45.3 2.9 1.7 1 0 0 1 1 1 1 Hormone receptor domain DUF1651 PF07864.11 OWF47718.1 - 2.8e-12 46.8 3.9 0.22 11.9 0.0 5.8 1 1 7 8 8 8 7 Protein of unknown function (DUF1651) Cytochrom_B559a PF00284.20 OWF47718.1 - 0.0022 17.7 8.4 21 5.0 0.0 7.6 3 2 9 12 12 12 3 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit RcsF PF16358.5 OWF47718.1 - 0.0057 16.7 19.0 33 4.6 0.0 7.3 1 1 4 7 7 7 4 RcsF lipoprotein Fibrinogen_BP PF08017.11 OWF47719.1 - 0.051 12.0 0.0 7.8 4.8 0.0 2.1 1 1 1 2 2 2 0 Fibrinogen binding protein Ribosomal_L28 PF00830.19 OWF47720.1 - 0.0042 17.2 0.1 0.0078 16.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Acetyltransf_16 PF05301.11 OWF47720.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 GGACT PF06094.12 OWF47721.1 - 0.012 16.2 0.1 0.027 15.1 0.1 1.6 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like EMP24_GP25L PF01105.24 OWF47721.1 - 0.23 11.4 2.5 0.25 11.2 0.6 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PTR2 PF00854.21 OWF47722.1 - 0.36 9.6 1.2 0.58 8.9 1.2 1.2 1 0 0 1 1 1 0 POT family DUF2730 PF10805.8 OWF47722.1 - 6.9 6.8 8.5 3.9 7.6 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Bactofilin PF04519.13 OWF47725.1 - 0.00017 21.8 26.5 0.2 12.0 8.1 3.5 1 1 1 2 2 2 2 Polymer-forming cytoskeletal SGP PF17228.2 OWF47725.1 - 0.29 12.0 17.2 87 4.1 0.6 4.9 1 1 2 3 3 3 0 Sulphur globule protein zf-CCHC PF00098.23 OWF47727.1 - 0.00018 21.4 1.6 0.00018 21.4 1.6 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 OWF47727.1 - 0.0064 16.2 0.5 0.014 15.1 0.5 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_2 PF13696.6 OWF47727.1 - 0.89 9.4 5.5 0.19 11.6 1.5 1.9 2 0 0 2 2 2 0 Zinc knuckle Tetraspanin PF00335.20 OWF47728.1 - 5e-45 154.0 11.6 5.6e-45 153.8 11.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2569 PF10754.9 OWF47728.1 - 0.021 15.2 3.1 1.5 9.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) CD20 PF04103.15 OWF47728.1 - 0.15 12.1 9.1 0.02 15.0 2.9 2.2 2 1 0 2 2 2 0 CD20-like family SUR7 PF06687.12 OWF47728.1 - 0.42 10.2 10.6 0.49 10.0 7.0 2.2 2 1 0 2 2 2 0 SUR7/PalI family DctQ PF04290.12 OWF47728.1 - 7.9 6.4 11.1 0.44 10.5 4.6 2.1 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component ATP-synt_ab PF00006.25 OWF47729.1 - 4.1e-72 242.3 0.0 7.5e-72 241.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OWF47729.1 - 7.9e-47 158.7 5.4 1.3e-46 158.0 5.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OWF47729.1 - 3.3e-17 62.8 1.5 8.5e-17 61.4 1.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 OWF47729.1 - 0.025 14.7 0.7 0.13 12.5 0.7 2.1 1 1 1 2 2 2 0 HAS barrel domain DUF4142 PF13628.6 OWF47729.1 - 0.17 12.1 2.4 0.33 11.2 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) DUF2096 PF09869.9 OWF47729.1 - 0.29 11.2 1.6 7.5 6.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Ras PF00071.22 OWF47730.1 - 2.5e-53 180.0 0.0 3e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47730.1 - 2.6e-19 69.6 0.0 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF47730.1 - 4.7e-11 42.4 0.0 5.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF47730.1 - 1.9e-05 24.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OWF47730.1 - 0.00056 19.5 0.0 0.0017 17.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OWF47730.1 - 0.0018 18.1 0.0 0.025 14.4 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 OWF47730.1 - 0.0083 15.7 0.0 0.048 13.2 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OWF47730.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OWF47730.1 - 0.08 13.3 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Det1 PF09737.9 OWF47731.1 - 1.1e-191 637.3 3.1 1.4e-191 637.0 3.1 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 KH_1 PF00013.29 OWF47732.1 - 2.1e-44 149.2 8.0 4.1e-18 65.0 0.9 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OWF47732.1 - 6.6e-16 57.9 4.3 0.00051 19.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OWF47732.1 - 3.4e-07 30.0 2.7 0.086 12.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OWF47732.1 - 3.6e-07 30.2 1.2 0.32 11.1 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain Spc7 PF08317.11 OWF47733.1 - 0.00056 18.9 2.5 0.00056 18.9 2.5 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein Prefoldin_2 PF01920.20 OWF47733.1 - 0.00087 19.2 1.3 0.00087 19.2 1.3 3.4 4 0 0 4 4 4 1 Prefoldin subunit COG5 PF10392.9 OWF47733.1 - 0.062 13.5 9.2 0.8 9.9 0.7 2.5 1 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF1825 PF08855.10 OWF47733.1 - 0.25 11.3 2.6 2.2 8.2 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) Fib_alpha PF08702.10 OWF47733.1 - 1.5 9.0 16.7 3.6 7.8 0.5 3.6 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OWF47733.1 - 3.3 8.4 16.1 6.1 7.5 1.7 4.8 1 1 2 4 4 4 0 SlyX DUF2019 PF09450.10 OWF47734.1 - 0.0051 16.7 2.7 0.071 13.1 0.3 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF2019) DUF802 PF05650.11 OWF47734.1 - 0.2 12.2 6.2 2.4 8.7 2.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF802) CdvA PF18822.1 OWF47734.1 - 0.21 11.4 16.3 0.21 11.4 0.9 4.5 3 1 0 4 4 4 0 CdvA-like coiled-coil domain ASPRs PF17641.2 OWF47734.1 - 4.3 7.6 8.8 0.71 10.2 1.7 2.9 3 0 0 3 3 3 0 Ancylostoma-associated secreted protein related RasGAP PF00616.19 OWF47735.1 - 1.6e-52 178.2 0.9 1.6e-52 178.2 0.9 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OWF47735.1 - 2.1e-37 128.4 9.9 2.1e-37 128.4 9.9 3.2 4 0 0 4 4 4 1 RasGAP C-terminus CH PF00307.31 OWF47735.1 - 2.8e-18 66.1 0.0 1.3e-17 63.9 0.0 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 OWF47735.1 - 3.7e-18 63.5 7.2 4e-05 23.0 0.1 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 OWF47735.1 - 0.021 14.6 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain Na_Ca_ex PF01699.24 OWF47736.1 - 4.9e-58 195.4 43.7 4e-31 108.0 19.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein VWA_2 PF13519.6 OWF47737.1 - 1.5e-12 48.1 0.0 1.5e-11 44.9 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain LRR_9 PF14580.6 OWF47738.1 - 9.3e-10 38.3 3.8 1.6e-07 31.0 3.8 2.2 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF47738.1 - 1.5e-09 37.9 10.4 2.2e-05 24.7 1.8 2.8 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF47738.1 - 3e-07 30.1 10.2 2.4e-05 24.0 0.1 2.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 OWF47738.1 - 0.0067 16.4 13.2 1.4 9.1 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 OWF47738.1 - 0.23 12.1 4.2 85 4.3 0.1 4.6 6 0 0 6 6 6 0 Leucine Rich Repeat PhyH PF05721.13 OWF47739.1 - 1.6e-19 71.0 0.0 3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-H2C2_2 PF13465.6 OWF47740.1 - 6.8e-73 238.1 108.4 1.9e-07 31.2 0.1 17.0 17 0 0 17 17 17 15 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47740.1 - 2.5e-51 169.4 131.0 0.0002 21.6 0.7 17.5 17 0 0 17 17 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47740.1 - 5.7e-51 166.7 120.9 0.00055 20.6 0.3 17.0 17 0 0 17 17 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF47740.1 - 1.4e-28 98.6 92.4 0.0068 16.7 2.1 17.2 17 0 0 17 17 17 12 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF47740.1 - 2e-19 69.3 96.0 0.0094 16.3 1.6 16.0 16 0 0 16 16 16 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF47740.1 - 4e-13 49.0 108.2 0.15 12.1 1.3 16.2 16 0 0 16 16 16 12 C2H2-type zinc finger DUF4764 PF15961.5 OWF47740.1 - 0.001 17.9 0.1 0.001 17.9 0.1 5.0 3 1 2 5 5 5 2 Domain of unknown function (DUF4764) BolA PF01722.18 OWF47740.1 - 0.0057 16.9 20.9 6.9 7.0 0.1 7.0 5 3 1 6 6 6 2 BolA-like protein zf-C2HE PF16278.5 OWF47740.1 - 0.14 12.6 0.2 0.14 12.6 0.2 13.9 5 2 9 14 14 14 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 OWF47740.1 - 0.22 11.8 59.5 0.93 9.8 1.1 8.3 1 1 7 8 8 8 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 OWF47740.1 - 2.5 7.9 0.0 0.4 10.5 0.1 12.0 14 0 0 14 14 13 0 zinc-finger C2H2-type SSTK-IP PF15836.5 OWF47742.1 - 0.0092 16.1 0.5 0.037 14.2 0.5 2.0 1 0 0 1 1 1 1 SSTK-interacting protein, TSSK6-activating co-chaperone protein OrsD PF12013.8 OWF47742.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D COG2 PF06148.11 OWF47742.1 - 1.2 9.2 15.6 3.9 7.6 1.7 3.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 OWF47742.1 - 9.6 6.5 7.8 17 5.8 0.3 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Methyltransf_7 PF03492.15 OWF47743.1 - 1.6e-29 103.2 0.2 1.8e-29 103.0 0.2 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Mlf1IP PF10248.9 OWF47744.1 - 6.2e-59 198.8 11.3 6.2e-59 198.8 11.3 1.7 2 0 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein CPG4 PF15481.6 OWF47745.1 - 0.00043 20.8 26.8 0.016 15.8 1.0 4.2 2 1 2 4 4 4 3 Chondroitin proteoglycan 4 ARTD15_N PF18084.1 OWF47745.1 - 0.11 12.7 0.7 16 5.8 0.0 3.7 4 1 0 4 4 4 0 ARTD15 N-terminal domain Nucleoplasmin PF03066.15 OWF47746.1 - 7.9e-25 87.3 0.1 7.9e-25 87.3 0.1 1.9 2 0 0 2 2 2 1 Nucleoplasmin/nucleophosmin domain NPL PF17800.1 OWF47746.1 - 0.00011 22.8 0.1 0.00011 22.8 0.1 2.6 2 1 0 2 2 2 1 Nucleoplasmin-like domain BUD22 PF09073.10 OWF47746.1 - 0.00033 20.1 20.5 0.00041 19.8 20.5 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 OWF47746.1 - 0.0045 16.5 27.1 0.0072 15.8 27.1 1.3 1 0 0 1 1 1 1 SDA1 Pho88 PF10032.9 OWF47746.1 - 0.032 13.5 0.0 0.098 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphate transport (Pho88) U3_snoRNA_assoc PF08297.11 OWF47746.1 - 1.4 9.7 25.4 1.1 10.0 4.2 2.4 2 0 0 2 2 2 0 U3 snoRNA associated RNase_H2_suC PF08615.11 OWF47746.1 - 2.3 8.4 9.2 1.2 9.3 4.7 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FGF PF00167.18 OWF47747.1 - 3.6e-15 56.2 0.2 3.6e-15 56.2 0.2 1.7 2 0 0 2 2 2 1 Fibroblast growth factor DUF3479 PF11965.8 OWF47748.1 - 0.028 14.5 11.5 1e+02 2.9 0.0 8.0 2 2 9 11 11 11 0 Domain of unknown function (DUF3479) Hormone_3 PF00159.18 OWF47748.1 - 0.13 12.3 26.4 3.3 7.9 0.1 8.6 5 4 4 10 10 10 0 Pancreatic hormone peptide DUF4744 PF15918.5 OWF47748.1 - 0.17 12.8 11.8 38 5.2 0.2 5.0 2 1 3 5 5 5 0 Domain of unknown function (DUF4744) CP_ATPgrasp_1 PF04174.13 OWF47748.1 - 6.4 5.7 6.8 51 2.7 0.0 4.5 2 1 5 7 7 7 0 A circularly permuted ATPgrasp DUF3479 PF11965.8 OWF47749.1 - 0.028 14.6 0.6 5.7 7.0 0.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3479) Hormone_3 PF00159.18 OWF47749.1 - 1.8 8.7 9.4 9.7 6.4 0.1 4.4 1 1 5 6 6 6 0 Pancreatic hormone peptide ThrE_2 PF12821.7 OWF47749.1 - 6.9 6.8 6.7 46 4.2 0.3 2.9 1 1 0 2 2 2 0 Threonine/Serine exporter, ThrE DUF4506 PF14958.6 OWF47750.1 - 1.4e-21 76.5 0.0 2.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) NID PF07292.13 OWF47751.1 - 0.00016 22.3 8.4 0.53 11.0 0.1 5.1 4 1 0 4 4 4 3 Nmi/IFP 35 domain (NID) CooT PF10133.9 OWF47751.1 - 0.0036 17.5 1.3 0.01 16.1 0.4 2.2 2 0 0 2 2 2 1 CO dehydrogenase accessory protein CooT RRM_1 PF00076.22 OWF47751.1 - 0.0038 17.0 2.0 6.3 6.7 0.1 4.5 4 2 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OWF47751.1 - 0.0081 16.1 0.0 3.2 7.8 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Macro PF01661.21 OWF47752.1 - 3.6e-26 91.5 0.1 6.5e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Macro domain Myc_N PF01056.18 OWF47753.1 - 0.055 13.4 0.5 0.076 12.9 0.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nup35_RRM_2 PF14605.6 OWF47753.1 - 0.069 13.2 0.0 9.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CooT PF10133.9 OWF47753.1 - 0.18 12.1 0.3 0.32 11.3 0.3 1.3 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT Ribosomal_60s PF00428.19 OWF47753.1 - 2.6 8.7 13.2 4.3 8.0 13.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Macro PF01661.21 OWF47755.1 - 1.5e-51 173.3 3.9 3.5e-21 75.4 0.0 3.9 4 0 0 4 4 4 3 Macro domain PARP PF00644.20 OWF47755.1 - 3.5e-25 88.8 1.7 3.3e-24 85.6 0.4 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 OWF47755.1 - 0.00057 20.4 0.0 0.0036 17.9 0.0 2.5 1 0 0 1 1 1 1 WWE domain NID PF07292.13 OWF47755.1 - 0.69 10.6 11.7 5.4 7.7 0.1 5.3 6 1 0 6 6 6 0 Nmi/IFP 35 domain (NID) Ribosomal_60s PF00428.19 OWF47755.1 - 1.3 9.6 11.6 1.4 9.6 9.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RICH PF05062.12 OWF47755.1 - 2.4 8.6 6.7 4.5 7.7 0.7 3.3 3 0 0 3 3 3 0 RICH domain Asp_protease_2 PF13650.6 OWF47758.1 - 6.9e-06 26.6 0.0 9.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OWF47758.1 - 3.3e-05 24.4 0.0 4.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease POC1 PF10450.9 OWF47758.1 - 0.09 11.7 0.0 0.095 11.7 0.0 1.1 1 0 0 1 1 1 0 POC1 chaperone RVP PF00077.20 OWF47758.1 - 0.12 12.7 0.2 0.95 9.8 0.0 2.0 1 1 1 2 2 2 0 Retroviral aspartyl protease TssN PF17555.2 OWF47759.1 - 0.0051 16.2 3.1 0.0051 16.2 3.1 3.1 3 0 0 3 3 3 3 Type VI secretion system, TssN COesterase PF00135.28 OWF47761.1 - 1.3e-133 446.6 0.0 1.5e-133 446.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47761.1 - 3.2e-07 30.4 0.0 1.2e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47761.1 - 0.00018 21.1 0.2 0.00046 19.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OWF47761.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.28 OWF47762.1 - 8.4e-136 453.8 0.0 1e-135 453.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47762.1 - 7e-08 32.6 0.2 2.2e-07 31.0 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47762.1 - 0.003 17.1 0.2 0.0045 16.5 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OWF47763.1 - 5.2e-137 457.8 0.0 6.1e-137 457.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47763.1 - 3.3e-10 40.2 0.1 1.1e-09 38.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47763.1 - 0.00021 20.8 0.1 0.00037 20.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OWF47763.1 - 0.055 13.1 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Say1_Mug180 PF10340.9 OWF47763.1 - 0.063 12.1 0.0 0.2 10.5 0.0 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase COesterase PF00135.28 OWF47764.1 - 1.7e-130 436.3 0.0 2e-130 436.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47764.1 - 7.7e-09 35.7 0.2 2.5e-08 34.1 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47764.1 - 0.002 17.7 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OWF47765.1 - 3.7e-134 448.4 0.0 4.4e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47765.1 - 9.8e-09 35.4 0.1 3.7e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47765.1 - 0.00037 20.0 0.0 0.00081 18.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family MBOAT PF03062.19 OWF47767.1 - 1.7e-26 93.5 9.6 2.6e-26 92.8 9.2 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sugar_transport PF06800.12 OWF47767.1 - 0.016 14.5 0.5 0.034 13.5 0.5 1.5 1 0 0 1 1 1 0 Sugar transport protein TACI-CRD2 PF09305.10 OWF47767.1 - 0.095 12.7 0.2 0.095 12.7 0.2 2.1 2 0 0 2 2 2 0 TACI, cysteine-rich domain DUF1925 PF09094.11 OWF47767.1 - 0.27 11.6 1.2 3.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) DUF751 PF05421.11 OWF47767.1 - 0.54 11.0 0.1 0.54 11.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF751) WD40 PF00400.32 OWF47768.1 - 1.7e-23 82.5 14.0 0.00077 20.2 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF47768.1 - 3.8e-05 23.9 0.4 1.3 9.4 0.2 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF47768.1 - 0.00011 21.0 0.9 2.4 6.7 0.0 3.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF47768.1 - 0.0011 18.3 0.0 0.73 9.1 0.1 2.5 1 1 2 3 3 3 3 WD40-like domain SH2 PF00017.24 OWF47769.1 - 5.8e-15 55.1 2.4 6e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 SH2 domain Pkinase PF00069.25 OWF47770.1 - 3.8e-79 265.8 0.0 7.2e-79 264.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF47770.1 - 3.1e-39 134.8 0.1 7.5e-38 130.3 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF47770.1 - 1.6e-07 30.6 0.3 1.6e-07 30.6 0.3 3.0 3 0 0 3 3 3 2 Haspin like kinase domain Kinase-like PF14531.6 OWF47770.1 - 0.0058 16.0 0.0 0.05 12.9 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 OWF47770.1 - 0.038 13.9 0.0 0.81 9.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kelch_1 PF01344.25 OWF47771.1 - 3.8e-84 276.1 22.6 6.2e-16 57.7 1.9 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF47771.1 - 1.8e-35 120.1 4.4 1.1e-06 28.7 0.1 6.3 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 OWF47771.1 - 9.3e-35 118.8 1.1 9.3e-35 118.8 1.1 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF47771.1 - 1.4e-31 109.0 1.6 2.5e-31 108.2 1.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 OWF47771.1 - 1.7e-24 85.5 9.4 4.2e-05 23.7 0.4 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF47771.1 - 5.2e-22 76.9 14.7 2.2e-05 24.2 0.5 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OWF47771.1 - 4.2e-20 71.5 7.0 0.00091 19.2 0.1 6.3 5 1 1 6 6 6 4 Galactose oxidase, central domain PQQ_3 PF13570.6 OWF47771.1 - 0.01 16.3 14.9 1.9 9.1 0.0 4.8 5 0 0 5 5 5 0 PQQ-like domain Kelch_5 PF13854.6 OWF47771.1 - 0.019 14.9 15.7 0.2 11.7 0.1 5.1 5 0 0 5 5 5 0 Kelch motif DUF3342 PF11822.8 OWF47771.1 - 0.085 13.1 1.9 0.67 10.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) Glyoxal_oxid_N PF07250.11 OWF47771.1 - 1.1 8.4 3.2 27 3.9 0.3 3.0 2 1 1 3 3 3 0 Glyoxal oxidase N-terminus Folliculin_C PF16692.5 OWF47773.1 - 2.8e-73 246.4 0.1 4e-73 245.9 0.1 1.2 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 OWF47773.1 - 9.8e-50 169.0 1.2 7.3e-49 166.2 0.1 2.7 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Sterile PF03015.19 OWF47773.1 - 0.02 15.1 0.5 0.75 10.1 0.1 2.5 2 0 0 2 2 2 0 Male sterility protein DNA_pol_phi PF04931.13 OWF47773.1 - 4.4 5.3 12.9 7.6 4.5 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CALM_bind PF16025.5 OWF47774.1 - 1.9e-15 57.1 3.0 1.9e-15 57.1 3.0 4.9 3 0 0 3 3 3 1 Calcium-dependent calmodulin binding LtuB PF17455.2 OWF47774.1 - 0.13 12.9 0.9 0.48 11.1 0.9 2.0 1 0 0 1 1 1 0 Late transcription unit B KH_1 PF00013.29 OWF47775.1 - 2.5e-37 126.5 38.9 1.6e-07 31.1 0.3 7.8 7 1 0 7 7 7 7 KH domain KH_2 PF07650.17 OWF47775.1 - 1.3e-08 34.5 44.1 0.1 12.4 0.0 11.2 9 3 1 10 10 10 4 KH domain LAL_C2 PF18603.1 OWF47775.1 - 7.9e-07 29.1 8.1 0.14 12.4 0.1 6.2 7 0 0 7 7 7 1 L-amino acid ligase C-terminal domain 2 ProRS-C_2 PF09181.10 OWF47775.1 - 1.5e-06 28.3 11.4 0.13 12.4 0.1 5.2 5 0 0 5 5 5 3 Prolyl-tRNA synthetase, C-terminal Glyco_tran_WecB PF03808.13 OWF47775.1 - 5.6e-06 26.4 2.3 2.4 8.1 0.0 5.7 4 1 1 6 6 6 1 Glycosyl transferase WecB/TagA/CpsF family PriA_C PF18074.1 OWF47775.1 - 0.00018 22.3 5.7 32 5.4 0.0 6.7 7 0 0 7 7 7 0 Primosomal protein N C-terminal domain PriX PF18689.1 OWF47775.1 - 0.00066 20.0 9.2 3.8 7.9 0.0 4.9 6 0 0 6 6 4 2 Primase X DUF3801 PF12687.7 OWF47775.1 - 0.0064 16.6 4.6 7.7 6.6 0.0 4.5 4 1 0 4 4 4 2 Protein of unknown function (DUF3801) DUF2277 PF10041.9 OWF47775.1 - 0.009 16.3 1.4 28 5.1 0.0 4.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) Rubrerythrin PF02915.17 OWF47775.1 - 0.016 15.6 1.9 61 4.0 0.0 4.0 3 2 0 4 4 3 0 Rubrerythrin KH_4 PF13083.6 OWF47775.1 - 0.03 14.2 17.9 11 6.0 0.0 6.7 7 0 0 7 7 6 0 KH domain LcrG PF07216.12 OWF47775.1 - 0.039 13.9 9.0 4.6 7.2 0.0 5.3 6 0 0 6 6 6 0 LcrG protein Ribosomal_S10 PF00338.22 OWF47775.1 - 0.048 13.9 3.2 19 5.6 0.0 5.0 5 0 0 5 5 5 0 Ribosomal protein S10p/S20e YtxH PF12732.7 OWF47775.1 - 0.073 13.6 2.2 18 6.0 0.0 4.5 4 1 0 4 4 4 0 YtxH-like protein Anillin_N PF16018.5 OWF47775.1 - 0.08 13.6 0.0 7.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Anillin N-terminus MIF4G_like_2 PF09090.11 OWF47775.1 - 0.081 12.4 3.5 44 3.4 0.0 4.3 5 0 0 5 5 5 0 MIF4G like Spt5-NGN PF03439.13 OWF47775.1 - 0.31 11.0 6.1 3 7.8 0.0 4.7 5 0 0 5 5 5 0 Early transcription elongation factor of RNA pol II, NGN section Carbpep_Y_N PF05388.11 OWF47775.1 - 5.5 7.6 5.2 21 5.7 0.0 4.0 5 1 1 6 6 5 0 Carboxypeptidase Y pro-peptide SicP-binding PF09119.10 OWF47775.1 - 10 6.2 10.3 9.2 6.3 0.2 4.8 6 0 0 6 6 6 0 SicP binding ADP_ribosyl_GH PF03747.14 OWF47776.1 - 2e-53 182.0 0.6 2.5e-53 181.7 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Flavodoxin_1 PF00258.25 OWF47776.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin IRS PF02174.17 OWF47777.1 - 2.5e-09 36.9 0.0 6.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 OWF47777.1 - 0.042 14.4 1.3 0.13 12.8 0.1 2.6 2 0 0 2 2 2 0 PH domain zf-CCCH PF00642.24 OWF47779.1 - 9.4e-19 66.8 36.6 2.7e-06 27.1 0.3 5.6 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF47779.1 - 1.1e-14 53.9 55.9 1e-06 28.6 2.0 7.3 7 1 0 7 7 7 4 Zinc finger domain Torus PF16131.5 OWF47779.1 - 2.7e-11 44.1 28.7 0.00035 21.2 0.2 5.4 1 1 4 5 5 5 4 Torus domain zf-CCHC PF00098.23 OWF47779.1 - 5.1e-10 39.0 15.8 2.2e-06 27.5 3.0 4.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCCH_3 PF15663.5 OWF47779.1 - 6.3e-10 39.2 24.2 4.9e-09 36.4 7.6 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 OWF47779.1 - 2.1e-05 24.2 0.4 2.1e-05 24.2 0.4 5.1 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OWF47779.1 - 0.00013 22.2 47.3 0.38 11.3 1.0 6.3 6 0 0 6 6 6 5 RNA-binding, Nab2-type zinc finger zf-CCHC_2 PF13696.6 OWF47779.1 - 0.0006 19.6 15.7 0.094 12.6 2.2 4.2 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 OWF47779.1 - 0.0023 17.8 6.9 0.41 10.6 1.9 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-C3H1 PF10650.9 OWF47779.1 - 0.024 14.3 0.5 0.024 14.3 0.5 5.2 5 0 0 5 5 5 0 Putative zinc-finger domain zf-CCHC_4 PF14392.6 OWF47779.1 - 0.04 13.7 6.0 2.4 8.0 0.3 2.7 2 0 0 2 2 2 0 Zinc knuckle Complex1_LYR PF05347.15 OWF47781.1 - 2e-09 37.4 0.3 3.8e-09 36.5 0.3 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OWF47781.1 - 0.00052 20.7 0.1 0.00081 20.1 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like LUC7 PF03194.15 OWF47782.1 - 3.9e-82 275.7 13.1 3.9e-82 275.7 13.1 2.3 1 1 2 3 3 3 1 LUC7 N_terminus YtxH PF12732.7 OWF47782.1 - 9.9 6.8 8.9 2.1 8.9 2.8 2.4 2 0 0 2 2 2 0 YtxH-like protein Acyl_transf_1 PF00698.21 OWF47783.1 - 8.8e-82 275.1 0.0 1.7e-81 274.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 OWF47783.1 - 1.5e-73 247.5 0.0 1.4e-72 244.3 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OWF47783.1 - 1.3e-50 171.8 0.0 3.7e-50 170.3 0.0 1.8 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 OWF47783.1 - 5.9e-37 126.3 0.1 2.6e-36 124.2 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OWF47783.1 - 4.3e-32 110.9 0.0 1.5e-31 109.1 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 OWF47783.1 - 4.9e-25 89.0 0.0 8.8e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain ADH_zinc_N PF00107.26 OWF47783.1 - 2e-18 66.6 0.0 9.1e-18 64.5 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.6 OWF47783.1 - 3.4e-17 62.6 0.0 2.3e-16 59.9 0.0 2.1 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 OWF47783.1 - 1.6e-14 55.1 0.0 1.4e-13 52.1 0.0 2.6 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 OWF47783.1 - 7.6e-09 35.8 0.3 1.8e-08 34.6 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OWF47783.1 - 4.1e-08 32.9 0.1 6.8e-07 28.9 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 OWF47783.1 - 7.8e-06 25.8 0.2 1.6e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 OWF47783.1 - 3.4e-05 23.3 0.1 8.4e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.12 OWF47783.1 - 0.015 16.0 0.2 0.048 14.4 0.2 1.9 1 0 0 1 1 1 0 Methyltransferase domain YjeF_N PF03853.15 OWF47783.1 - 0.032 14.1 0.2 0.67 9.8 0.0 3.0 4 0 0 4 4 4 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 OWF47783.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Tektin PF03148.14 OWF47784.1 - 6e-150 499.3 28.4 8.7e-150 498.7 28.4 1.2 1 0 0 1 1 1 1 Tektin family Syntaxin-6_N PF09177.11 OWF47784.1 - 0.16 12.6 19.1 0.12 13.0 3.3 4.3 2 2 1 3 3 3 0 Syntaxin 6, N-terminal SNCAIP_SNCA_bd PF16700.5 OWF47784.1 - 0.76 9.5 3.6 0.5 10.1 0.1 2.5 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain FliD_C PF07195.12 OWF47784.1 - 1.3 8.4 8.3 1.7 8.0 1.2 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Baculo_PEP_C PF04513.12 OWF47784.1 - 1.3 9.1 8.4 11 6.0 0.7 3.4 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM76 PF16046.5 OWF47784.1 - 4.4 6.6 13.0 0.34 10.2 4.3 2.2 2 0 0 2 2 2 0 FAM76 protein ParA PF10609.9 OWF47785.1 - 2.2e-102 341.7 0.0 2.6e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OWF47785.1 - 3.7e-10 39.9 0.0 1.8e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OWF47785.1 - 1.1e-06 28.8 0.2 0.00019 21.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 OWF47785.1 - 1.8e-06 27.5 0.4 1.6e-05 24.4 0.4 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OWF47785.1 - 4.3e-06 26.1 1.0 6.6e-05 22.2 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 OWF47785.1 - 4.9e-06 26.2 0.1 0.017 14.6 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 OWF47785.1 - 3.9e-05 23.3 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OWF47785.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 OWF47785.1 - 0.0026 17.7 0.3 0.0043 17.0 0.3 1.3 1 0 0 1 1 1 1 NACHT domain CLP1_P PF16575.5 OWF47785.1 - 0.0081 16.0 0.0 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 OWF47785.1 - 0.0084 15.1 0.2 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 OWF47785.1 - 0.009 16.0 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE UPF0179 PF03684.13 OWF47785.1 - 0.011 15.7 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) CBP_BcsQ PF06564.12 OWF47785.1 - 0.02 14.4 0.1 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 OWF47785.1 - 0.022 14.0 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 OWF47785.1 - 0.03 14.7 0.1 0.086 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 OWF47785.1 - 0.04 14.3 0.1 0.076 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 OWF47785.1 - 0.055 13.1 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DnaB_C PF03796.15 OWF47785.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DAP3 PF10236.9 OWF47785.1 - 0.14 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ploopntkinase3 PF18751.1 OWF47785.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 COesterase PF00135.28 OWF47786.1 - 4.3e-110 369.0 0.0 7.7e-79 265.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF47786.1 - 1.5e-11 44.5 0.0 1.7e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF47786.1 - 0.0023 17.4 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2369 PF10179.9 OWF47788.1 - 4.2e-20 71.9 5.1 7.8e-17 61.4 1.3 2.9 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 OWF47788.1 - 6.7e-07 29.6 4.0 0.025 14.9 0.0 4.5 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF47788.1 - 0.0036 17.8 5.5 0.041 14.5 0.4 4.1 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain DUF1410 PF07198.11 OWF47788.1 - 2.6 8.6 0.0 2.6 8.6 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1410) Colipase-like PF15083.6 OWF47789.1 - 0.021 14.9 33.4 0.57 10.3 11.3 3.4 1 1 2 3 3 3 0 Colipase-like NEXCaM_BD PF16644.5 OWF47789.1 - 0.038 14.2 11.2 5.6 7.3 0.3 4.6 1 1 4 5 5 5 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Mucin-like PF16058.5 OWF47789.1 - 0.32 11.1 13.6 0.027 14.6 3.9 2.4 1 1 2 3 3 3 0 Mucin-like Glyco_hydro_18 PF00704.28 OWF47790.1 - 1.4e-80 271.3 0.0 1.8e-80 271.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF47790.1 - 0.012 15.8 8.9 0.028 14.6 8.9 1.7 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Glyco_hydro_85 PF03644.13 OWF47790.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 85 Glyco_hydro_18 PF00704.28 OWF47791.1 - 1.1e-90 304.6 4.0 1.4e-90 304.2 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF47791.1 - 1.3e-09 38.1 15.2 2.2e-07 30.9 0.9 2.6 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Cas9_Topo PF17894.1 OWF47791.1 - 0.097 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Glyco_hydro_18 PF00704.28 OWF47792.1 - 3.8e-178 591.9 0.0 4e-88 296.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF47792.1 - 1.5e-05 25.0 17.3 0.00017 21.7 0.8 2.7 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 OWF47793.1 - 2.1e-166 553.3 10.5 3.7e-92 309.4 3.6 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 DUF5012 PF16404.5 OWF47793.1 - 0.087 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) Fz PF01392.22 OWF47794.1 - 7e-06 26.6 2.7 1.3e-05 25.8 2.7 1.4 1 0 0 1 1 1 1 Fz domain CCDC154 PF15450.6 OWF47795.1 - 7.4e-37 127.1 80.8 7.4e-37 127.1 80.8 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 154 WD40 PF00400.32 OWF47796.1 - 2e-18 66.4 21.8 1.1e-07 32.4 0.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 OWF47796.1 - 8.5e-15 54.8 0.1 8e-14 51.7 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 OWF47796.1 - 2.4e-06 27.8 0.7 0.0048 17.2 0.1 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 OWF47796.1 - 0.083 11.8 0.4 0.22 10.4 0.4 1.7 1 1 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain HRM PF02793.22 OWF47796.1 - 0.14 12.4 0.5 0.4 11.0 0.5 1.8 1 0 0 1 1 1 0 Hormone receptor domain Saw1 PF11561.8 OWF47796.1 - 3.2 7.2 4.5 1.3 8.5 0.5 2.0 2 0 0 2 2 2 0 Single strand annealing-weakened 1 FAM176 PF14851.6 OWF47796.1 - 4.8 6.8 13.4 0.15 11.7 3.1 2.3 2 0 0 2 2 2 0 FAM176 family Fe_hyd_lg_C PF02906.14 OWF47797.1 - 1.9e-75 253.7 0.0 3e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 OWF47797.1 - 1.6e-06 28.1 0.0 3.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit FAD_syn PF06574.12 OWF47797.1 - 0.0024 17.8 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD synthetase DbpA PF03880.15 OWF47797.1 - 0.015 15.3 0.0 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain Plasmodium_Vir PF05795.11 OWF47798.1 - 0.55 9.6 10.7 0.97 8.8 10.7 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GalKase_gal_bdg PF10509.9 OWF47799.1 - 6.8e-23 80.0 0.0 1.3e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 OWF47799.1 - 5e-15 55.6 0.0 9.6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OWF47799.1 - 6.3e-09 35.9 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Tet_JBP PF12851.7 OWF47800.1 - 4.2e-101 338.7 0.1 1e-100 337.4 0.1 1.7 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily SAM_Ste50p PF09235.10 OWF47800.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Cofilin_ADF PF00241.20 OWF47801.1 - 0.0043 16.9 0.0 0.0047 16.7 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cadherin PF00028.17 OWF47802.1 - 0 2458.1 395.0 9e-18 64.5 0.2 84.1 84 0 0 84 84 84 84 Cadherin domain RET_CLD1 PF17756.1 OWF47802.1 - 2.3e-24 86.1 0.0 2.2 8.6 0.0 21.6 28 0 0 28 28 28 4 RET Cadherin like domain 1 Cadherin_pro PF08758.11 OWF47802.1 - 2.9e-09 37.0 17.3 43 4.4 0.0 18.3 21 0 0 21 21 21 0 Cadherin prodomain like Y_Y_Y PF07495.13 OWF47802.1 - 0.002 18.0 32.0 6 6.9 0.0 16.0 19 0 0 19 19 19 1 Y_Y_Y domain NAGLU_N PF12971.7 OWF47802.1 - 0.14 12.0 0.1 64 3.4 0.0 5.9 4 0 0 4 4 4 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain RUN PF02759.19 OWF47803.1 - 5.7e-14 52.2 0.1 9.3e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 RUN domain PID PF00640.23 OWF47803.1 - 0.00011 22.2 0.1 0.00026 21.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) IRK PF01007.20 OWF47804.1 - 2.7e-43 147.2 1.6 8.2e-43 145.6 1.7 1.7 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 OWF47804.1 - 4.7e-40 137.0 0.0 6.5e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 OWF47804.1 - 0.0019 18.1 4.9 0.0019 18.1 4.9 1.9 1 1 0 1 1 1 1 Ion channel BioY PF02632.14 OWF47804.1 - 0.069 13.2 1.3 0.11 12.6 1.3 1.3 1 0 0 1 1 1 0 BioY family IRK PF01007.20 OWF47805.1 - 2e-51 173.5 0.2 3.4e-51 172.8 0.2 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 OWF47805.1 - 2.7e-43 147.6 0.0 3.9e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 OWF47805.1 - 2.5e-06 27.3 1.3 4.3e-06 26.6 1.3 1.4 1 0 0 1 1 1 1 Ion channel IRK_C PF17655.1 OWF47806.1 - 5.1e-77 257.4 0.0 7.2e-77 256.9 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OWF47806.1 - 6.6e-62 207.5 1.4 9.8e-62 207.0 1.4 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OWF47806.1 - 0.00013 21.8 0.7 0.00026 20.9 0.7 1.5 1 0 0 1 1 1 1 Ion channel TrkH PF02386.16 OWF47806.1 - 0.11 10.9 1.3 0.16 10.4 1.3 1.1 1 0 0 1 1 1 0 Cation transport protein Pkinase_Tyr PF07714.17 OWF47807.1 - 9.1e-36 123.5 0.0 1.9e-35 122.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF47807.1 - 2e-35 122.4 0.0 3.4e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 OWF47807.1 - 7.5e-34 116.2 4.9 4.5e-12 46.4 0.4 5.7 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) LRR_8 PF13855.6 OWF47807.1 - 1.1e-26 92.4 30.7 1e-08 34.8 0.4 6.5 5 1 1 6 6 6 5 Leucine rich repeat Ank_4 PF13637.6 OWF47807.1 - 8.8e-25 86.8 9.3 0.0015 19.1 0.1 7.1 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF47807.1 - 9.2e-23 77.9 15.8 0.0015 18.8 0.1 9.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OWF47807.1 - 6.9e-22 77.2 5.1 0.0063 16.8 0.0 6.8 5 1 1 6 6 6 5 Ankyrin repeats (many copies) LRR_4 PF12799.7 OWF47807.1 - 1.9e-19 69.5 42.6 1.5e-05 25.3 5.4 8.7 5 3 5 10 10 9 8 Leucine Rich repeats (2 copies) COR PF16095.5 OWF47807.1 - 8.5e-18 64.9 0.0 2.7e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF47807.1 - 2.5e-17 63.2 0.0 4.2e-14 52.8 0.0 2.6 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ank PF00023.30 OWF47807.1 - 1.5e-14 53.6 10.0 0.001 19.4 0.1 7.4 7 0 0 7 7 6 2 Ankyrin repeat Ras PF00071.22 OWF47807.1 - 2.9e-06 27.0 0.0 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Ras family LRR_1 PF00560.33 OWF47807.1 - 0.0076 16.7 25.6 8.5 7.4 0.5 10.1 10 0 0 10 10 9 1 Leucine Rich Repeat Arf PF00025.21 OWF47807.1 - 0.044 13.2 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family LRR_6 PF13516.6 OWF47807.1 - 0.062 13.4 34.6 0.96 9.7 0.0 9.6 10 0 0 10 10 10 0 Leucine Rich repeat AAA_16 PF13191.6 OWF47807.1 - 0.18 12.1 0.0 0.49 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Paf67 PF10255.9 OWF47808.1 - 2.7e-176 586.5 7.7 2.7e-176 586.5 7.7 1.6 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 OWF47808.1 - 0.0013 18.4 0.2 0.81 9.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF47808.1 - 0.009 16.1 0.6 0.48 10.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat PCI PF01399.27 OWF47808.1 - 0.019 15.5 2.1 0.075 13.6 2.1 2.2 1 1 0 1 1 1 0 PCI domain Med15_fungi PF05397.12 OWF47808.1 - 0.081 13.2 2.6 0.21 11.9 2.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 15 DEAD PF00270.29 OWF47809.1 - 7.5e-47 159.3 0.0 1.3e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF47809.1 - 4.5e-28 97.8 0.1 3.1e-27 95.1 0.0 2.4 2 2 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF47809.1 - 9.4e-06 25.7 0.0 4.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OWF47809.1 - 0.0036 16.5 0.1 0.0066 15.7 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Macoilin PF09726.9 OWF47809.1 - 3.9 5.9 9.6 5.3 5.5 9.6 1.1 1 0 0 1 1 1 0 Macoilin family 7tm_1 PF00001.21 OWF47810.1 - 1e-51 175.8 14.6 1.4e-51 175.4 14.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF47810.1 - 9.5e-12 45.2 10.2 1.3e-11 44.8 10.2 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF47810.1 - 5.4e-11 42.4 12.6 9.1e-11 41.6 12.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF47810.1 - 2.3 7.8 16.5 0.38 10.4 11.6 2.0 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Extensin_2 PF04554.13 OWF47811.1 - 1.3e-29 102.0 302.6 0.91 9.7 14.6 22.0 1 1 21 22 22 22 17 Extensin-like region Amino_oxidase PF01593.24 OWF47812.1 - 2.5e-54 185.3 0.0 2.4e-34 119.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF47812.1 - 1.3e-13 51.0 0.1 2.8e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF47812.1 - 1.1e-08 34.6 0.1 2.6e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OWF47812.1 - 8.6e-07 28.8 0.9 1.5e-06 28.1 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OWF47812.1 - 1.8e-06 27.3 0.3 3.4e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OWF47812.1 - 6.8e-06 25.7 0.1 1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF47812.1 - 4.2e-05 22.8 0.2 0.00087 18.4 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 OWF47812.1 - 0.00017 20.8 0.2 0.015 14.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 OWF47812.1 - 0.00069 18.4 0.3 0.0017 17.2 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OWF47812.1 - 0.0013 18.0 0.1 0.011 14.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF47812.1 - 0.013 16.1 0.1 0.028 15.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF47812.1 - 0.037 14.0 0.3 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.15 OWF47812.1 - 0.067 11.7 0.0 0.098 11.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 OWF47812.1 - 0.1 11.8 0.2 0.49 9.6 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 OWF47812.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OWF47812.1 - 0.25 10.6 0.3 0.67 9.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Clathrin-link PF09268.10 OWF47813.1 - 6.4e-07 28.6 11.6 8.7 5.8 0.1 7.9 8 0 0 8 8 8 5 Clathrin, heavy-chain linker IFS PF16718.5 OWF47813.1 - 5.6e-06 26.6 7.0 0.4 10.8 0.2 4.1 1 1 2 4 4 4 3 Immunity factor for SPN UTP15_C PF09384.10 OWF47813.1 - 0.00019 21.1 0.5 5.7 6.6 0.0 4.1 1 1 4 5 5 5 2 UTP15 C terminal Tnp_22_dsRBD PF17490.2 OWF47813.1 - 0.01 15.8 3.4 1.7e+02 2.3 0.0 6.0 3 3 5 8 8 8 0 L1 transposable element dsRBD-like domain PH_11 PF15413.6 OWF47813.1 - 2.6 8.5 7.6 13 6.3 0.0 3.9 1 1 2 3 3 3 0 Pleckstrin homology domain PP-binding PF00550.25 OWF47814.1 - 1.6e-10 41.2 0.2 2.3e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OWF47814.1 - 0.11 12.7 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Acyl-carrier Ras PF00071.22 OWF47815.1 - 2.7e-55 186.4 0.0 3.1e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF47815.1 - 1.1e-22 80.5 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF47815.1 - 3.9e-08 32.9 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CagD PF16567.5 OWF47815.1 - 0.09 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD WD40 PF00400.32 OWF47816.1 - 7.4e-12 45.6 12.1 0.0025 18.6 0.9 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF47816.1 - 9.7e-06 25.8 0.5 1.8 8.9 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF47816.1 - 9.9e-05 21.8 0.1 1.7 7.9 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 OWF47816.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Lactonase PF10282.9 OWF47816.1 - 0.012 14.9 0.0 0.28 10.4 0.0 2.1 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase_Tyr PF07714.17 OWF47817.1 - 3.2e-60 203.6 0.0 5.3e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF47817.1 - 4.5e-28 98.3 0.0 8.7e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF47817.1 - 0.05 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Sec7 PF01369.20 OWF47818.1 - 2.2e-74 249.1 0.1 3.3e-74 248.5 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OWF47818.1 - 4.1e-24 85.1 0.3 9.2e-24 84.0 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF47818.1 - 1.9e-08 34.7 0.4 1.9e-08 34.7 0.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 OWF47818.1 - 0.006 16.7 0.0 0.066 13.3 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 OWF47818.1 - 0.026 14.8 0.2 0.93 9.8 0.0 2.7 2 1 1 3 3 3 0 Pleckstrin homology domain eIF3_N PF09440.10 OWF47818.1 - 0.14 12.6 4.0 2.7 8.4 4.0 2.3 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain APG6_N PF17675.1 OWF47818.1 - 0.25 11.9 3.5 0.4 11.2 3.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region UCH PF00443.29 OWF47819.1 - 2.5e-53 181.2 6.3 2.5e-53 181.2 6.3 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF47819.1 - 7.7e-25 88.2 10.0 7.7e-25 88.2 10.0 3.3 3 1 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase SSXT PF05030.12 OWF47820.1 - 0.0071 15.9 2.3 0.023 14.3 0.8 2.0 2 0 0 2 2 2 1 SSXT protein (N-terminal region) DUF5344 PF17279.2 OWF47820.1 - 0.018 15.6 3.2 0.018 15.6 3.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5344) Prenyltransf PF01255.19 OWF47820.1 - 0.018 14.5 0.9 0.023 14.2 0.9 1.1 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase PriC PF07445.12 OWF47820.1 - 0.019 14.9 2.4 0.022 14.7 2.4 1.1 1 0 0 1 1 1 0 Primosomal replication protein priC HisKA_3 PF07730.13 OWF47820.1 - 0.021 15.4 0.1 11 6.7 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase DUF2524 PF10732.9 OWF47820.1 - 0.022 15.0 3.9 0.028 14.7 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) Med30 PF11315.8 OWF47820.1 - 0.038 14.2 2.3 0.13 12.4 0.9 1.9 1 1 1 2 2 2 0 Mediator complex subunit 30 LUD_dom PF02589.15 OWF47820.1 - 0.058 13.1 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 LUD domain Syntaxin-6_N PF09177.11 OWF47820.1 - 0.058 14.0 4.1 0.075 13.6 1.6 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1798 PF08807.10 OWF47820.1 - 0.059 13.5 0.7 0.09 12.9 0.7 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Prominin PF05478.11 OWF47820.1 - 0.16 9.9 2.6 0.19 9.7 2.6 1.0 1 0 0 1 1 1 0 Prominin YtxH PF12732.7 OWF47820.1 - 0.37 11.4 2.1 0.67 10.5 2.1 1.6 1 1 0 1 1 1 0 YtxH-like protein Snapin_Pallidin PF14712.6 OWF47820.1 - 0.41 11.1 8.6 40 4.7 6.0 2.9 2 1 0 2 2 2 0 Snapin/Pallidin DUF948 PF06103.11 OWF47820.1 - 1.2 9.5 3.5 7.8 6.8 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) VirE1 PF12189.8 OWF47822.1 - 0.02 15.0 16.8 10 6.3 1.1 5.2 2 2 4 6 6 6 0 Single-strand DNA-binding protein Oxygenase-NA PF09859.9 OWF47822.1 - 0.043 13.4 1.3 8.4 5.9 0.0 2.9 2 1 1 3 3 3 0 Oxygenase, catalysing oxidative methylation of damaged DNA SRI PF08236.11 OWF47822.1 - 0.096 12.9 2.7 12 6.1 0.8 3.1 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain COLFI PF01410.18 OWF47822.1 - 0.93 8.7 13.7 2.2 7.5 1.6 2.9 2 2 0 2 2 2 0 Fibrillar collagen C-terminal domain Lectin_C PF00059.21 OWF47823.1 - 2.6e-18 66.7 0.3 4e-18 66.1 0.3 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF47823.1 - 0.1 12.2 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like zf-H2C2_2 PF13465.6 OWF47824.1 - 2.5e-38 128.8 49.6 3e-10 40.0 0.7 7.8 8 0 0 8 8 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47824.1 - 8.3e-30 101.6 54.6 9.1e-07 29.0 0.4 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47824.1 - 1.8e-20 71.9 53.4 0.00047 20.8 1.3 7.8 8 0 0 8 8 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF47824.1 - 5.9e-15 55.1 20.5 0.00073 19.8 0.3 7.2 7 1 1 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF47824.1 - 2.7e-12 46.4 53.6 0.00012 22.0 0.7 7.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 OWF47824.1 - 2e-10 40.7 33.8 0.014 15.8 0.4 7.2 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OWF47824.1 - 0.00039 20.1 39.3 0.092 12.5 0.4 7.9 8 0 0 8 8 8 4 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OWF47824.1 - 0.0012 18.7 21.5 0.6 10.1 0.1 6.6 6 0 0 6 6 6 2 zinc-finger of a C2HC-type BolA PF01722.18 OWF47824.1 - 0.0019 18.5 1.0 20 5.5 0.0 4.0 1 1 2 3 3 3 0 BolA-like protein FYVE PF01363.21 OWF47824.1 - 0.03 14.4 32.3 5.5 7.2 11.3 4.3 2 2 1 3 3 3 0 FYVE zinc finger zf-CHCC PF10276.9 OWF47824.1 - 0.29 11.2 14.9 1.6 8.9 0.1 5.4 6 0 0 6 6 6 0 Zinc-finger domain zf-C2H2_2 PF12756.7 OWF47824.1 - 3.7 7.9 28.4 27 5.2 0.1 5.9 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) PHF5 PF03660.14 OWF47824.1 - 4.1 7.6 16.2 5.6 7.2 1.9 3.2 1 1 1 3 3 3 0 PHF5-like protein LRR_8 PF13855.6 OWF47825.1 - 4.6e-35 119.2 24.8 8.8e-14 51.0 1.6 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OWF47825.1 - 2.9e-20 72.0 30.8 1.1e-06 28.8 1.1 6.6 4 2 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF47825.1 - 3.3e-09 36.8 1.3 1.5e-06 28.2 0.0 2.9 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF47825.1 - 1.4e-08 34.1 25.5 1.8 9.4 0.0 9.6 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.6 OWF47825.1 - 1.9e-07 30.6 30.7 0.53 10.5 0.6 8.6 9 0 0 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.6 OWF47825.1 - 0.00037 20.1 5.4 0.016 14.7 1.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRRCT PF01463.24 OWF47825.1 - 0.006 17.0 0.0 0.02 15.4 0.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain GpcrRhopsn4 PF10192.9 OWF47826.1 - 2.6e-65 220.4 18.1 3.6e-65 219.9 18.1 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 OWF47826.1 - 8.1e-05 22.0 6.4 0.00013 21.3 6.4 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor TPMT PF05724.11 OWF47826.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Tetraspanin PF00335.20 OWF47826.1 - 4.6 6.9 8.2 1.1 8.9 0.1 2.6 2 1 0 2 2 2 0 Tetraspanin family LRR_8 PF13855.6 OWF47827.1 - 7.8e-84 275.4 83.1 1.2e-14 53.8 0.6 7.8 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 OWF47827.1 - 5.8e-26 90.1 50.9 7.4e-06 26.2 4.3 8.9 2 2 11 13 13 13 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF47827.1 - 2e-19 69.8 0.0 4.7e-09 36.3 0.5 3.9 2 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF47827.1 - 1.1e-12 47.9 21.3 0.00082 18.9 1.4 5.6 1 1 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 OWF47827.1 - 7.9e-11 41.0 43.7 2.9 8.8 0.0 13.7 16 0 0 16 16 16 6 Leucine Rich Repeat fn3 PF00041.21 OWF47827.1 - 0.00013 22.2 1.5 0.00029 21.1 1.5 1.5 1 0 0 1 1 1 1 Fibronectin type III domain LRR_6 PF13516.6 OWF47827.1 - 0.00044 20.1 54.5 2.6 8.3 1.0 12.8 14 0 0 14 14 14 6 Leucine Rich repeat Pur_ac_phosph_N PF16656.5 OWF47827.1 - 0.1 13.2 1.5 0.19 12.3 1.5 1.4 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Sulfotransfer_2 PF03567.14 OWF47828.1 - 3.7e-35 122.0 2.2 2.5e-34 119.4 0.3 2.2 2 0 0 2 2 2 1 Sulfotransferase family Neur_chan_memb PF02932.16 OWF47828.1 - 0.078 13.0 0.5 0.14 12.2 0.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SPOB_ab PF14682.6 OWF47828.1 - 0.12 12.4 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal Ig_3 PF13927.6 OWF47829.1 - 1e-20 74.1 11.6 1.8e-14 54.1 0.8 3.9 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF47829.1 - 2.1e-14 53.6 13.1 6.3e-10 39.3 1.2 4.2 3 2 1 4 4 4 2 Immunoglobulin domain I-set PF07679.16 OWF47829.1 - 2.3e-12 46.8 3.8 2.8e-09 36.9 0.2 4.5 4 2 0 4 4 4 1 Immunoglobulin I-set domain ig PF00047.25 OWF47829.1 - 2.4e-11 43.7 7.8 7.6e-05 22.8 0.3 4.2 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 OWF47829.1 - 4.7e-09 36.2 6.2 1.5e-05 25.0 0.4 2.8 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF47829.1 - 7.7e-09 35.7 1.6 0.012 15.7 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 OWF47829.1 - 1.2e-05 25.6 0.7 0.0019 18.6 0.0 3.5 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ninjurin PF04923.12 OWF47829.1 - 0.017 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Ninjurin Ig_4 PF16680.5 OWF47829.1 - 0.022 15.0 0.1 0.13 12.5 0.1 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain GUCT PF08152.12 OWF47829.1 - 0.039 14.3 0.1 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 GUCT (NUC152) domain Gp138_N PF18352.1 OWF47829.1 - 0.097 12.8 0.4 0.5 10.5 0.1 2.1 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain C1-set PF07654.15 OWF47829.1 - 0.53 10.7 5.3 3.2 8.2 0.1 3.9 3 2 0 3 3 3 0 Immunoglobulin C1-set domain Ntox37 PF15535.6 OWF47831.1 - 2.8e-06 27.7 0.9 1.5 9.3 0.4 4.5 1 1 1 2 2 2 2 Bacterial toxin 37 Transglut_C PF00927.22 OWF47831.1 - 0.00085 19.4 0.1 24 5.2 0.0 4.4 1 1 3 5 5 5 1 Transglutaminase family, C-terminal ig like domain Antistasin PF02822.14 OWF47831.1 - 0.14 12.8 16.7 53 4.6 0.5 5.8 1 1 1 2 2 2 0 Antistasin family Hormone_5 PF00184.17 OWF47831.1 - 0.18 12.6 12.8 8.8 7.2 3.4 3.2 1 1 1 2 2 2 0 Neurohypophysial hormones, C-terminal Domain Peptidase_S31 PF05578.12 OWF47831.1 - 0.27 10.7 9.7 0.39 10.2 3.3 2.3 1 1 1 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 GalKase_gal_bdg PF10509.9 OWF47831.1 - 6.9 6.3 9.2 2.1e+02 1.6 0.1 5.1 4 2 2 6 6 6 0 Galactokinase galactose-binding signature I-set PF07679.16 OWF47832.1 - 1.3e-20 73.3 1.7 5.9e-05 23.1 0.0 5.0 4 1 0 4 4 4 4 Immunoglobulin I-set domain CUB PF00431.20 OWF47832.1 - 3e-19 69.4 0.0 2.2e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 CUB domain V-set PF07686.17 OWF47832.1 - 4.7e-13 49.2 5.0 0.043 14.0 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin V-set domain Ig_3 PF13927.6 OWF47832.1 - 1.8e-12 47.7 6.3 0.0033 18.0 0.2 4.7 4 0 0 4 4 4 4 Immunoglobulin domain FRD2 PF03197.13 OWF47832.1 - 0.082 13.2 0.8 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage FRD2 protein Ig_GlcNase PF18368.1 OWF47832.1 - 0.091 12.9 0.3 0.44 10.7 0.1 2.1 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain Izumo-Ig PF16706.5 OWF47832.1 - 0.15 12.1 0.1 14 5.8 0.0 3.0 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain ABC2_membrane_3 PF12698.7 OWF47833.1 - 1.6e-36 126.1 15.3 2.1e-36 125.7 15.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 OWF47833.1 - 7.2e-36 123.6 16.5 7.2e-36 123.6 16.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OWF47833.1 - 5.6e-29 101.4 0.0 9.5e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OWF47833.1 - 4.4e-11 43.2 1.0 1.5e-06 28.3 0.6 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 OWF47833.1 - 0.00017 21.0 7.3 0.00023 20.5 7.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 OWF47833.1 - 0.0072 16.7 0.1 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OWF47833.1 - 0.0098 15.8 0.0 0.025 14.5 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OWF47833.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 OWF47833.1 - 0.043 14.3 0.1 0.091 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OWF47833.1 - 0.047 14.1 0.2 0.15 12.5 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF47833.1 - 0.079 13.2 0.8 0.35 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OWF47833.1 - 0.11 11.7 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 OWF47833.1 - 0.13 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CLP1_P PF16575.5 OWF47833.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop U79_P34 PF03064.16 OWF47835.1 - 0.055 12.8 14.0 0.066 12.6 14.0 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RPN6_C_helix PF18503.1 OWF47837.1 - 0.034 13.9 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Lipase_GDSL_2 PF13472.6 OWF47840.1 - 6e-08 33.3 0.0 7.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AP_endonuc_2 PF01261.24 OWF47840.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel OSK PF17182.4 OWF47840.1 - 0.092 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 OSK domain PTS_2-RNA PF01885.16 OWF47841.1 - 5.9e-22 78.6 0.1 6.6e-22 78.4 0.1 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DDE_1 PF03184.19 OWF47842.1 - 1.2e-24 87.0 0.0 1.8e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OWF47842.1 - 0.00019 21.2 0.0 0.0029 17.4 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Hydrolase_like PF13242.6 OWF47844.1 - 2.4e-21 75.6 0.0 5.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OWF47844.1 - 2.9e-15 56.2 0.0 4.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OWF47844.1 - 4.4e-09 36.7 0.1 4.7e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OWF47844.1 - 8.8e-08 32.7 0.3 1e-06 29.2 0.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C2H2_4 PF13894.6 OWF47845.1 - 1.1e-84 271.6 478.1 0.0033 18.1 0.3 57.6 58 0 0 58 58 58 48 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF47845.1 - 1.9e-63 207.5 484.2 0.00098 19.5 0.2 55.2 55 0 0 55 55 55 46 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF47845.1 - 4e-16 58.6 376.0 0.00011 22.4 0.1 51.5 58 0 0 58 58 58 22 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF47845.1 - 1.5e-09 37.8 295.0 0.02 15.2 0.5 44.7 46 0 0 46 46 46 19 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF47845.1 - 2.3e-06 27.5 17.8 5.9e-06 26.1 2.2 47.5 49 1 1 50 50 50 20 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF47845.1 - 7.8e-05 22.3 12.5 0.0061 16.3 0.4 33.6 36 0 0 36 36 36 12 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 OWF47845.1 - 0.0019 18.8 3.4 0.0019 18.8 3.4 26.8 17 7 9 28 28 28 9 Zinc finger C2H2-type, 3 repeats CdiI PF07262.11 OWF47846.1 - 0.015 15.0 0.3 0.018 14.8 0.3 1.1 1 0 0 1 1 1 0 CDI immunity protein DUF2689 PF10894.8 OWF47846.1 - 0.061 13.1 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) Methyltrn_RNA_3 PF02598.17 OWF47847.1 - 2.4e-107 358.7 0.0 2.9e-107 358.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Tho2 PF11262.8 OWF47847.1 - 2.5 7.2 7.9 3.9 6.6 7.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RhoGAP PF00620.27 OWF47848.1 - 2.2e-41 141.2 0.8 2.2e-41 141.2 0.8 2.9 4 0 0 4 4 4 1 RhoGAP domain Nod1 PF17114.5 OWF47848.1 - 0.024 14.8 1.4 0.095 12.8 1.4 2.1 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 G-patch PF01585.23 OWF47851.1 - 3.4e-13 49.3 0.3 7.5e-13 48.2 0.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OWF47851.1 - 0.011 15.8 0.2 0.011 15.8 0.2 4.5 5 0 0 5 5 5 0 G-patch domain An_peroxidase PF03098.15 OWF47853.1 - 4e-147 491.0 0.0 7e-147 490.2 0.0 1.4 2 0 0 2 2 2 1 Animal haem peroxidase HSP70 PF00012.20 OWF47854.1 - 6.4e-11 41.1 0.1 1.7e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein HSP70 PF00012.20 OWF47855.1 - 6.6e-06 24.6 0.0 0.0058 14.9 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein HSP70 PF00012.20 OWF47856.1 - 1.4e-13 49.9 0.0 1.9e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein DUF2154 PF09922.9 OWF47856.1 - 0.11 12.4 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF RteC PF09357.10 OWF47857.1 - 0.026 14.2 2.7 0.037 13.7 2.3 1.3 1 1 0 1 1 1 0 RteC protein HSP70 PF00012.20 OWF47858.1 - 8.3e-09 34.2 0.1 1.1e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 OWF47860.1 - 3.7e-09 35.3 0.2 2.7e-06 25.9 0.1 2.3 2 0 0 2 2 2 2 Hsp70 protein Antistasin PF02822.14 OWF47861.1 - 8.8e-13 48.6 145.8 2e-06 28.3 11.4 12.3 10 4 0 10 10 10 8 Antistasin family RRM_7 PF16367.5 OWF47862.1 - 1.2e-27 95.9 3.9 1.9e-26 92.0 1.0 3.6 3 1 0 3 3 3 1 RNA recognition motif CEBP1_N PF16368.5 OWF47862.1 - 4.6e-27 95.3 4.0 2.4e-22 79.8 2.6 2.3 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein 1 N-terminus CEBP_ZZ PF16366.5 OWF47862.1 - 2.6e-24 85.2 8.7 2.6e-24 85.2 8.7 2.2 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 OWF47862.1 - 3.6e-09 36.3 0.0 0.0037 17.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_GPD PF05954.11 OWF47862.1 - 2.3 7.4 8.7 1.5 8.0 0.5 2.2 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) Spt20 PF12090.8 OWF47862.1 - 9.3 5.8 26.4 3.2 7.3 10.2 2.2 2 0 0 2 2 2 0 Spt20 family zf-H2C2_2 PF13465.6 OWF47863.1 - 6.5e-79 257.1 84.6 5.8e-09 36.0 1.0 12.6 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47863.1 - 7.4e-52 171.0 88.7 1.6e-05 25.1 3.3 12.4 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47863.1 - 1.3e-37 125.1 84.3 0.00087 19.9 0.8 12.3 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF47863.1 - 4.6e-24 84.1 29.4 0.004 17.4 0.2 11.5 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF47863.1 - 3.7e-17 62.1 67.3 0.0081 16.5 1.2 12.0 12 0 0 12 12 12 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF47863.1 - 7.3e-07 29.0 72.3 0.0058 16.6 0.1 12.6 12 1 0 12 12 12 6 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OWF47863.1 - 0.00082 19.2 52.4 0.17 11.8 0.1 10.5 11 0 0 11 11 11 3 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 OWF47863.1 - 0.00098 18.8 1.7 0.00098 18.8 1.7 12.0 11 4 0 11 11 11 2 C2H2-type zinc-finger domain zf_UBZ PF18439.1 OWF47863.1 - 0.0018 17.8 45.8 4 7.1 0.1 10.7 12 0 0 12 12 12 4 Ubiquitin-Binding Zinc Finger BolA PF01722.18 OWF47863.1 - 0.0019 18.5 14.9 86 3.5 0.1 6.7 2 2 3 5 5 5 0 BolA-like protein GAGA PF09237.11 OWF47863.1 - 0.016 15.0 29.0 0.32 10.8 0.0 7.9 2 1 8 10 10 10 0 GAGA factor zf-C2H2_11 PF16622.5 OWF47863.1 - 0.028 14.2 1.2 0.028 14.2 1.2 10.8 13 0 0 13 13 13 0 zinc-finger C2H2-type Zf_RING PF16744.5 OWF47863.1 - 0.093 12.8 38.5 14 5.9 0.1 10.6 1 1 11 12 12 12 0 KIAA1045 RING finger YqzL PF14006.6 OWF47863.1 - 0.39 11.1 1.3 9.5 6.7 0.0 3.2 3 0 0 3 3 3 0 YqzL-like protein zinc_ribbon_15 PF17032.5 OWF47863.1 - 0.45 11.3 43.4 1.2 9.9 0.3 6.8 1 1 7 9 9 8 0 zinc-ribbon family zf-C2H2_9 PF16293.5 OWF47863.1 - 0.67 9.8 23.5 3.5 7.5 0.0 8.1 8 3 2 10 10 9 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 OWF47863.1 - 0.69 10.1 50.6 0.9 9.7 2.0 8.3 5 2 4 9 9 9 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 OWF47863.1 - 0.74 9.9 0.0 0.74 9.9 0.0 10.4 11 1 0 11 11 10 0 Sec23/Sec24 zinc finger Zn-C2H2_12 PF18112.1 OWF47863.1 - 0.94 10.0 0.1 0.94 10.0 0.1 6.9 8 0 0 8 8 7 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 OWF47864.1 - 2e-64 211.3 60.4 6.3e-10 39.0 0.1 10.2 11 0 0 11 11 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 OWF47864.1 - 2.6e-32 109.5 57.8 3.5e-05 24.0 1.0 10.0 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF47864.1 - 4.8e-30 101.6 58.4 0.00074 20.2 0.8 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF47864.1 - 7.7e-13 47.9 33.9 0.016 15.0 0.2 9.1 10 0 0 10 10 9 5 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 OWF47864.1 - 7.9e-12 44.9 52.7 0.012 15.6 0.5 10.2 10 0 0 10 10 10 6 C2H2-type zinc finger zf-Di19 PF05605.12 OWF47864.1 - 5.8e-10 39.3 32.0 0.00029 21.1 0.7 6.1 5 1 1 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 OWF47864.1 - 9.4e-10 38.5 36.9 1.2 9.4 0.7 8.9 7 2 2 9 9 9 5 Zinc ribbon domain zf-C2H2_8 PF15909.5 OWF47864.1 - 4.1e-09 36.6 25.9 0.00053 20.2 1.7 4.9 1 1 2 4 4 4 3 C2H2-type zinc ribbon DUF3268 PF11672.8 OWF47864.1 - 3.3e-08 33.9 17.7 0.058 13.7 0.1 5.4 5 1 1 6 6 6 4 zinc-finger-containing domain Elf1 PF05129.13 OWF47864.1 - 6.3e-07 29.4 32.3 0.01 15.8 1.1 6.7 1 1 7 8 8 8 6 Transcription elongation factor Elf1 like BolA PF01722.18 OWF47864.1 - 2e-06 28.0 11.9 3.1 8.2 0.7 6.4 1 1 4 6 6 6 1 BolA-like protein zf-C2HC_2 PF13913.6 OWF47864.1 - 3.2e-06 26.9 38.6 0.28 11.1 0.1 10.3 10 0 0 10 10 10 2 zinc-finger of a C2HC-type Desulfoferrod_N PF06397.12 OWF47864.1 - 1.7e-05 24.3 35.3 0.15 11.7 0.3 9.7 10 0 0 10 10 10 2 Desulfoferrodoxin, N-terminal domain DZR PF12773.7 OWF47864.1 - 4.6e-05 23.3 22.8 66 3.6 9.5 5.7 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 OWF47864.1 - 8.4e-05 22.4 37.7 0.39 10.6 2.8 8.1 1 1 8 9 9 9 4 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 OWF47864.1 - 0.00011 22.8 25.9 0.87 10.4 1.5 5.6 2 1 3 5 5 5 3 zinc-ribbon family zf-C2H2_3rep PF18868.1 OWF47864.1 - 0.00014 22.5 33.9 0.18 12.5 0.2 8.5 1 1 6 7 7 7 1 Zinc finger C2H2-type, 3 repeats zf-Sec23_Sec24 PF04810.15 OWF47864.1 - 0.00015 21.7 29.8 7.8 6.6 0.0 9.6 9 1 1 10 10 10 0 Sec23/Sec24 zinc finger zf_UBZ PF18439.1 OWF47864.1 - 0.00024 20.6 39.3 0.3 10.7 0.1 10.4 11 0 0 11 11 11 2 Ubiquitin-Binding Zinc Finger HypA PF01155.19 OWF47864.1 - 0.0003 20.8 24.7 0.58 10.2 0.5 5.8 1 1 5 6 6 6 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 OWF47864.1 - 0.002 18.3 41.4 4.1 7.7 1.0 9.5 9 1 1 10 10 9 1 AN1-like Zinc finger Zn_ribbon_SprT PF17283.2 OWF47864.1 - 0.0036 17.2 25.1 0.39 10.6 0.3 6.4 5 2 3 8 8 7 4 SprT-like zinc ribbon domain FYVE PF01363.21 OWF47864.1 - 0.0054 16.8 34.8 8.4 6.6 5.8 6.7 1 1 4 5 5 5 0 FYVE zinc finger ZZ PF00569.17 OWF47864.1 - 0.011 15.6 26.9 17 5.3 0.1 8.5 9 0 0 9 9 9 0 Zinc finger, ZZ type zf-C2H2_jaz PF12171.8 OWF47864.1 - 0.013 15.8 35.0 3.4 8.1 0.1 8.8 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding Trm112p PF03966.16 OWF47864.1 - 0.019 15.5 6.2 2.7 8.6 0.1 4.3 3 1 0 3 3 3 0 Trm112p-like protein ADK_lid PF05191.14 OWF47864.1 - 0.02 14.9 32.8 1.1 9.3 4.5 7.1 6 2 1 7 7 7 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 OWF47864.1 - 0.02 15.2 40.5 2.7 8.4 0.1 8.7 2 1 7 9 9 9 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.16 OWF47864.1 - 0.028 14.7 47.4 9.6 6.6 0.1 9.4 2 1 2 6 6 6 0 C1 domain zinc-ribbons_6 PF07191.12 OWF47864.1 - 0.042 13.8 27.7 1.1e+02 2.9 4.0 7.5 1 1 2 3 3 3 0 zinc-ribbons zf-FCS PF06467.14 OWF47864.1 - 0.048 13.6 37.3 1.3 9.0 0.2 9.3 8 2 2 10 10 10 0 MYM-type Zinc finger with FCS sequence motif TerY_C PF15616.6 OWF47864.1 - 0.074 13.2 14.3 1.7 8.8 0.1 4.7 3 2 1 4 4 4 0 TerY-C metal binding domain Scramblase PF03803.15 OWF47864.1 - 0.13 11.6 7.0 0.4 9.9 0.7 2.3 1 1 2 3 3 3 0 Scramblase Cys_rich_CPXG PF14255.6 OWF47864.1 - 0.3 11.0 20.8 24 4.9 0.1 7.9 8 2 0 8 8 8 0 Cysteine-rich CPXCG GAGA PF09237.11 OWF47864.1 - 1.8 8.4 12.9 12 5.8 0.7 5.4 3 2 2 6 6 6 0 GAGA factor DUF4428 PF14471.6 OWF47864.1 - 3.1 7.8 31.8 12 5.9 0.2 8.1 7 2 0 7 7 7 0 Domain of unknown function (DUF4428) Tim44 PF04280.15 OWF47865.1 - 0.0099 16.0 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Tim44-like domain C1q PF00386.21 OWF47866.1 - 9.6e-22 77.5 0.6 1.2e-21 77.2 0.6 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF47866.1 - 5.6e-08 32.8 0.2 7.3e-08 32.4 0.2 1.1 1 0 0 1 1 1 1 BclA C-terminal domain SH3_2 PF07653.17 OWF47866.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain FliMN_C PF01052.20 OWF47866.1 - 0.15 12.0 0.0 0.73 9.9 0.0 1.9 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term zf-UBR PF02207.20 OWF47867.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.0 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) VWA_2 PF13519.6 OWF47868.1 - 4.6e-10 40.1 0.0 0.0013 19.4 0.0 2.8 2 0 0 2 2 2 2 von Willebrand factor type A domain Galactosyl_T PF01762.21 OWF47869.1 - 3.6e-39 134.6 0.1 5.5e-39 134.0 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase 7tm_1 PF00001.21 OWF47870.1 - 6.7e-43 146.9 12.8 8.5e-43 146.6 12.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 OWF47870.1 - 9.2e-08 31.8 10.6 1.4e-07 31.2 10.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Dicty_CAR PF05462.11 OWF47870.1 - 3.6e-05 23.1 0.1 3.6e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7TM_GPCR_Srsx PF10320.9 OWF47870.1 - 0.00011 21.7 12.5 0.00058 19.3 12.5 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF47870.1 - 0.00034 20.0 16.0 0.22 10.8 16.0 3.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Ocular_alb PF02101.15 OWF47870.1 - 0.00035 19.6 0.2 0.00064 18.8 0.2 1.4 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_4 PF13853.6 OWF47870.1 - 0.00049 19.9 11.3 0.0014 18.4 8.4 2.3 1 1 1 2 2 2 1 Olfactory receptor PIG-F PF06699.11 OWF47870.1 - 0.0093 16.1 0.6 0.0093 16.1 0.6 1.6 2 0 0 2 2 2 1 GPI biosynthesis protein family Pig-F DUF3671 PF12420.8 OWF47870.1 - 1.5 8.9 10.2 1.3 9.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function Claudin_3 PF06653.11 OWF47871.1 - 4.7e-08 33.2 6.5 6.2e-08 32.8 6.5 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 OWF47871.1 - 9.8e-06 25.4 14.9 0.00038 20.3 14.9 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MIG-14_Wnt-bd PF06664.12 OWF47871.1 - 0.00075 18.8 7.7 0.00089 18.6 7.4 1.3 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Amastin PF07344.11 OWF47871.1 - 0.003 17.4 9.1 0.0033 17.3 7.8 1.8 1 1 0 1 1 1 1 Amastin surface glycoprotein FtsX PF02687.21 OWF47871.1 - 0.077 13.5 0.4 0.077 13.5 0.4 2.8 2 1 0 2 2 2 0 FtsX-like permease family DVL PF08137.12 OWF47871.1 - 0.14 12.1 0.5 0.26 11.2 0.5 1.5 1 0 0 1 1 1 0 DVL family Med26 PF08711.11 OWF47872.1 - 1.7e-11 43.9 1.9 2e-11 43.7 0.4 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 OWF47872.1 - 3.2e-06 27.6 2.1 8.7e-06 26.2 2.0 1.9 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain LEDGF PF11467.8 OWF47872.1 - 0.051 13.2 0.3 0.051 13.2 0.3 2.1 2 1 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Tubulin PF00091.25 OWF47873.1 - 6.7e-56 189.6 0.0 8.1e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 OWF47873.1 - 3.8e-05 24.0 0.0 9.1e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OWF47873.1 - 0.023 14.4 0.0 0.055 13.1 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain Tubulin_2 PF13809.6 OWF47873.1 - 0.023 13.9 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Kri1_C PF12936.7 OWF47876.1 - 1.3e-29 102.2 1.5 1.3e-29 102.2 1.5 5.7 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 OWF47876.1 - 1e-17 64.6 26.2 1e-17 64.6 26.2 7.8 6 4 0 6 6 6 1 KRI1-like family Rubredoxin PF00301.20 OWF47877.1 - 9.6e-13 47.9 31.7 1.4 9.0 0.2 14.8 16 0 0 16 16 16 1 Rubredoxin Glyc_hyd_38C_2 PF18230.1 OWF47877.1 - 6.1e-11 42.3 21.1 0.055 13.6 0.5 7.8 1 1 7 8 8 8 6 Glycosyl hydrolases family 38 C-terminal sub-domain Inp1 PF12634.7 OWF47877.1 - 8.7e-07 29.0 5.1 16 5.5 0.0 9.3 1 1 1 2 2 2 1 Inheritance of peroxisomes protein 1 CD45 PF12567.8 OWF47877.1 - 5.8e-06 26.2 32.5 6.7 6.8 0.4 10.0 1 1 10 13 13 13 6 Leukocyte receptor CD45 DUF2650 PF10853.8 OWF47877.1 - 1.6e-05 24.5 32.2 78 3.1 0.0 13.5 14 0 0 14 14 14 0 Protein of unknown function (DUF2650) SRCR PF00530.18 OWF47877.1 - 7.3e-05 23.2 39.7 5.5 7.6 2.3 9.5 1 1 11 12 12 12 5 Scavenger receptor cysteine-rich domain DUF1589 PF07628.11 OWF47877.1 - 0.0046 17.1 14.9 2.9 8.0 0.2 6.1 1 1 10 11 11 11 2 Protein of unknown function (DUF1589) TILa PF12714.7 OWF47877.1 - 0.084 12.8 59.8 12 6.0 0.4 14.8 3 2 13 16 16 16 0 TILa domain DOMON PF03351.17 OWF47878.1 - 3.9e-37 127.2 1.4 8.2e-20 71.3 0.0 2.9 2 0 0 2 2 2 2 DOMON domain Reeler PF02014.16 OWF47878.1 - 2e-24 86.8 0.1 8e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Reeler domain Cytochrom_B561 PF03188.16 OWF47878.1 - 3.1e-09 37.1 5.7 9.5e-09 35.5 5.7 1.9 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Glycoprotein PF03409.15 OWF47878.1 - 0.0071 15.2 15.0 0.35 9.7 12.8 2.3 2 0 0 2 2 2 2 Transmembrane glycoprotein Pox_A14 PF05767.12 OWF47878.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Dicty_REP PF05086.12 OWF47878.1 - 7.8 4.3 10.0 16 3.3 10.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tma16 PF11176.8 OWF47879.1 - 0.016 15.1 2.5 0.016 15.1 2.5 2.5 2 1 1 3 3 3 0 Translation machinery-associated protein 16 Spt5_N PF11942.8 OWF47879.1 - 1.6 9.8 12.0 4.7 8.2 12.0 1.7 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal eIF-3_zeta PF05091.12 OWF47879.1 - 5 6.0 6.6 5.8 5.8 6.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Fasciclin PF02469.22 OWF47880.1 - 2e-92 306.1 4.3 2.6e-26 92.3 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain DUF211 PF02680.14 OWF47880.1 - 0.98 9.6 6.5 8.1 6.7 0.2 4.1 4 1 0 4 4 4 0 Uncharacterized ArCR, COG1888 LRR_4 PF12799.7 OWF47881.1 - 9.5e-19 67.2 21.0 2.6e-06 27.7 1.4 5.6 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF47881.1 - 3.6e-17 61.9 22.3 2.2e-06 27.3 3.7 4.8 4 1 1 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 OWF47881.1 - 1.9e-07 30.8 8.0 0.00021 20.8 1.6 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OWF47881.1 - 4.9e-06 26.2 13.2 2.4 8.4 0.0 7.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 OWF47881.1 - 0.0007 19.8 16.7 4.6 8.2 0.3 8.1 8 0 0 8 8 8 1 Leucine Rich Repeat CLZ PF16526.5 OWF47881.1 - 0.11 12.9 3.6 0.25 11.7 1.6 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FERM_N_2 PF18038.1 OWF47881.1 - 0.32 11.8 1.6 1.1 10.1 0.1 2.6 3 0 0 3 3 3 0 FERM N-terminal domain Bacillus_HBL PF05791.11 OWF47882.1 - 0.017 15.0 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF1943 PF09172.11 OWF47884.1 - 1e-12 47.9 0.1 2.1e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DUF1081 PF06448.11 OWF47884.1 - 1.7e-06 28.4 0.0 4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1081) VWD PF00094.25 OWF47884.1 - 7.4e-05 23.1 1.7 0.006 16.9 0.0 4.0 3 1 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.11 OWF47884.1 - 0.89 10.0 6.5 2.1 8.8 6.5 1.7 1 0 0 1 1 1 0 C8 domain Cadherin PF00028.17 OWF47885.1 - 7.3e-35 119.3 13.4 5.7e-12 45.9 0.1 5.2 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 OWF47885.1 - 0.0016 18.4 5.9 0.95 9.5 0.3 4.0 4 0 0 4 4 4 2 Cadherin-like Protocadherin PF08374.11 OWF47885.1 - 0.0048 16.9 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 OWF47885.1 - 0.08 13.8 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 OWF47885.1 - 0.7 10.0 3.5 1.9 8.6 3.5 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 OWF47885.1 - 0.95 9.4 6.6 2.1 8.3 6.6 1.5 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 OWF47885.1 - 1.3 8.9 6.2 3.4 7.5 6.2 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2970 PF11174.8 OWF47885.1 - 4.4 7.2 8.8 12 5.8 8.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Cadherin PF00028.17 OWF47886.1 - 2.9e-32 111.0 13.6 1.1e-09 38.7 0.0 5.2 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 OWF47886.1 - 0.00063 19.7 7.5 0.69 9.9 0.2 4.0 4 0 0 4 4 4 2 Cadherin-like Syndecan PF01034.20 OWF47886.1 - 7.4 6.6 6.8 15 5.6 6.8 1.5 1 0 0 1 1 1 0 Syndecan domain DUF229 PF02995.17 OWF47888.1 - 1.8e-120 402.9 0.3 1.9e-119 399.6 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF47888.1 - 2.4e-06 27.2 0.1 3.6e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Sulfatase TMEM173 PF15009.6 OWF47889.1 - 8.9e-46 156.4 0.0 1.3e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 173 TIR_2 PF13676.6 OWF47889.1 - 4.3e-19 69.3 0.0 8.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF47889.1 - 2.9e-14 53.2 0.1 5.7e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 OWF47889.1 - 0.005 17.2 1.7 0.01 16.2 0.3 2.1 2 1 1 3 3 3 1 MTH538 TIR-like domain (DUF1863) TIR-like PF10137.9 OWF47889.1 - 0.059 13.3 0.1 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain SAM_3 PF18016.1 OWF47890.1 - 0.0017 18.1 0.1 0.084 12.7 0.0 3.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Ovate PF04844.13 OWF47890.1 - 0.0034 17.4 0.6 3.1 7.9 0.0 3.1 3 0 0 3 3 3 2 Transcriptional repressor, ovate NifT PF06988.11 OWF47890.1 - 0.05 13.4 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 NifT/FixU protein EGF PF00008.27 OWF47891.1 - 1.1e-25 89.6 101.3 1.4e-09 38.1 4.6 7.8 8 0 0 8 8 8 5 EGF-like domain hEGF PF12661.7 OWF47891.1 - 1.3e-10 41.5 81.9 2.5e-05 24.7 3.1 8.8 8 0 0 8 8 8 4 Human growth factor-like EGF EGF_2 PF07974.13 OWF47891.1 - 0.0038 17.6 33.5 0.007 16.7 8.7 7.7 8 0 0 8 8 8 5 EGF-like domain Protocadherin PF08374.11 OWF47891.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protocadherin EGF_3 PF12947.7 OWF47891.1 - 2.3 8.5 84.9 0.039 14.1 3.9 8.4 6 3 0 7 7 7 0 EGF domain Plasmod_Pvs28 PF06247.11 OWF47891.1 - 6.7 7.1 74.8 0.33 11.3 10.4 7.5 7 1 1 8 8 8 0 Pvs28 EGF domain Ank_4 PF13637.6 OWF47892.1 - 2.5e-44 149.1 2.2 4e-10 40.0 0.0 6.1 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF47892.1 - 1.3e-42 144.3 2.6 1.1e-13 51.6 0.0 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF47892.1 - 8.6e-36 121.5 4.4 1.1e-08 35.2 0.0 7.4 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF47892.1 - 7.6e-27 90.4 3.2 0.0073 16.7 0.0 8.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 OWF47892.1 - 5.2e-21 74.1 8.4 0.00017 21.9 0.1 8.2 8 0 0 8 8 8 4 Ankyrin repeat DUF1843 PF08898.10 OWF47892.1 - 0.11 13.0 0.0 18 6.0 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) BST2 PF16716.5 OWF47892.1 - 0.33 11.6 5.4 0.94 10.1 5.4 1.8 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 OWF47892.1 - 0.72 9.6 8.4 2.6 7.9 7.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Pox_A_type_inc PF04508.12 OWF47892.1 - 1.1 9.2 7.1 0.97 9.4 0.2 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 OWF47892.1 - 1.2 9.0 8.2 2 8.4 0.2 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 OWF47892.1 - 2.3 7.5 9.2 3.6 6.8 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 OWF47892.1 - 2.9 7.9 14.4 0.4 10.7 10.2 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 OWF47892.1 - 4.5 8.1 13.2 6.1 7.6 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) NUFIP1 PF10453.9 OWF47893.1 - 1.6e-13 50.2 2.6 1.6e-13 50.2 2.6 2.8 4 0 0 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 OWF47893.1 - 0.00049 20.3 0.6 0.00049 20.3 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OWF47893.1 - 0.0095 16.7 2.3 0.084 13.8 0.2 2.7 1 1 1 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF47893.1 - 0.013 15.9 2.5 0.16 12.5 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 OWF47893.1 - 0.071 13.5 3.1 0.25 11.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type UCH PF00443.29 OWF47894.1 - 1.7e-54 185.1 0.0 2.4e-50 171.4 0.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 OWF47894.1 - 1.1e-05 25.7 6.8 1.1e-05 25.7 6.8 3.9 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF47894.1 - 5.4e-05 23.1 3.5 0.00031 20.7 3.5 2.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF47894.1 - 0.00061 19.7 6.2 0.00061 19.7 6.2 3.0 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF47894.1 - 0.0013 18.6 6.9 0.0013 18.6 6.9 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF47894.1 - 0.0016 18.2 5.3 0.0016 18.2 5.3 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF47894.1 - 0.003 17.4 7.7 0.003 17.4 7.7 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.14 OWF47894.1 - 0.0099 15.7 0.1 0.0099 15.7 0.1 4.2 4 0 0 4 4 4 1 Zinc finger found in FPG and IleRS zf-C3HC4_4 PF15227.6 OWF47894.1 - 0.18 12.0 14.5 0.019 15.1 8.2 2.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 OWF47894.1 - 4.6 7.2 8.9 6.5 6.7 2.9 2.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DnaJ PF00226.31 OWF47895.1 - 2.2e-19 69.4 0.1 2.2e-19 69.4 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain DUF3990 PF13151.6 OWF47895.1 - 0.019 14.7 0.8 0.031 14.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) DUF1514 PF07438.11 OWF47895.1 - 0.5 10.3 0.1 0.5 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) Herpes_UL33 PF03581.13 OWF47896.1 - 2.7e-06 27.6 3.0 63 4.0 0.0 5.9 6 0 0 6 6 6 0 Herpesvirus UL33-like protein ssDBP PF17878.1 OWF47896.1 - 0.00043 20.4 0.0 2.5 8.4 0.0 3.6 1 1 3 4 4 4 2 Single-stranded DNA-binding protein SPK PF04435.18 OWF47896.1 - 0.0019 18.6 1.1 3.3 8.2 0.3 3.6 1 1 0 2 2 2 1 Domain of unknown function (DUF545) CODH_A_N PF18537.1 OWF47896.1 - 0.0035 17.3 0.2 35 4.5 0.0 4.3 3 2 1 5 5 5 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Afi1 PF07792.12 OWF47896.1 - 0.0048 17.4 1.4 36 4.9 0.1 4.0 4 1 1 5 5 5 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF5078 PF16877.5 OWF47896.1 - 0.019 15.5 0.4 6.5 7.3 0.1 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF5078) zf-RVT PF13966.6 OWF47896.1 - 0.019 15.6 0.5 11 6.8 0.0 3.3 1 1 3 4 4 4 0 zinc-binding in reverse transcriptase Ntox6 PF15544.6 OWF47896.1 - 0.023 14.3 0.1 3.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Bacterial toxin 6 Dehalogenase PF13486.6 OWF47896.1 - 0.028 13.8 6.9 8.7 5.6 1.1 3.7 1 1 2 3 3 3 0 Reductive dehalogenase subunit KH_dom-like PF14714.6 OWF47896.1 - 0.046 14.0 0.2 19 5.6 0.0 2.8 1 1 3 4 4 4 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal DUF192 PF02643.15 OWF47896.1 - 0.067 13.3 3.5 3.1 8.0 3.5 2.4 1 1 0 1 1 1 0 Uncharacterized ACR, COG1430 RAG2_PHD PF13341.6 OWF47896.1 - 0.073 13.1 7.2 8.5 6.5 0.4 4.3 1 1 3 4 4 4 0 RAG2 PHD domain Cu-oxidase_3 PF07732.15 OWF47896.1 - 0.19 11.8 6.0 6.6 6.8 0.1 3.1 1 1 2 3 3 3 0 Multicopper oxidase ketoacyl-synt PF00109.26 OWF47896.1 - 0.4 10.2 5.5 4.3 6.8 0.3 3.2 1 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Renin_r PF07850.14 OWF47896.1 - 1.8 9.2 8.6 2.8 8.6 0.4 3.6 1 1 4 5 5 5 0 Renin receptor-like protein DUF1581 PF07619.11 OWF47896.1 - 3.3 7.9 7.0 1.8e+02 2.3 0.0 4.6 2 1 4 6 6 6 0 Protein of unknown function (DUF1581) Fn_bind PF02986.14 OWF47896.1 - 5.2 6.9 7.7 1.4e+02 2.4 0.1 4.2 4 0 0 4 4 4 0 Fibronectin binding repeat RhoGEF PF00621.20 OWF47897.1 - 1.8e-33 116.3 3.5 4.5e-33 115.0 3.5 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 OWF47897.1 - 5.1e-24 84.8 1.0 5e-13 49.5 0.4 3.1 2 0 0 2 2 2 2 PH domain FERM_C PF09380.10 OWF47897.1 - 7.9e-21 74.3 2.0 1.9e-20 73.0 1.6 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FA PF08736.11 OWF47897.1 - 1.3e-15 57.2 5.3 1.7e-15 56.8 2.8 2.5 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_M PF00373.18 OWF47897.1 - 5.6e-14 52.6 0.5 1.5e-13 51.2 0.1 2.0 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 OWF47897.1 - 7.4e-11 41.8 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain IQ_SEC7_PH PF16453.5 OWF47897.1 - 1.7e-06 28.1 0.4 5.9e-06 26.3 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 OWF47897.1 - 0.00097 19.0 7.2 0.12 12.2 0.0 3.2 3 1 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 OWF47897.1 - 0.0016 18.8 7.0 0.014 15.7 1.4 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 OWF47897.1 - 0.0021 18.3 1.2 0.47 10.8 0.0 3.3 2 1 1 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 OWF47897.1 - 0.18 12.3 6.8 2 8.9 2.1 3.8 3 1 0 3 3 3 0 Pleckstrin homology domain FliJ PF02050.16 OWF47897.1 - 1.8 8.8 4.9 1.1 9.4 2.2 2.1 2 1 0 2 2 1 0 Flagellar FliJ protein TSC22 PF01166.18 OWF47898.1 - 8.4e-27 93.3 4.7 2e-26 92.1 4.7 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 OWF47898.1 - 0.00029 21.4 1.7 0.00076 20.1 1.7 1.7 1 0 0 1 1 1 1 Initiation control protein YabA PGP_phosphatase PF09419.10 OWF47898.1 - 0.0025 17.5 0.1 0.0049 16.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase K-box PF01486.17 OWF47898.1 - 0.006 16.7 2.3 0.012 15.8 2.3 1.4 1 0 0 1 1 1 1 K-box region Nnf1 PF03980.14 OWF47898.1 - 0.0084 16.5 0.3 0.018 15.4 0.3 1.5 1 0 0 1 1 1 1 Nnf1 ZapB PF06005.12 OWF47898.1 - 0.013 16.0 4.6 0.027 14.9 4.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 OWF47898.1 - 0.03 14.1 2.5 0.057 13.2 2.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 OWF47898.1 - 0.23 11.4 2.4 0.49 10.3 2.4 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 OWF47898.1 - 0.96 9.6 4.4 1.6 8.8 4.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF1241 PF06840.11 OWF47899.1 - 1.4e-49 167.5 0.1 2e-49 167.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) APG17 PF04108.12 OWF47899.1 - 0.023 13.8 0.1 0.03 13.4 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 GCP_C_terminal PF04130.13 OWF47899.1 - 0.041 13.4 0.2 0.054 13.0 0.2 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal TIP120 PF08623.10 OWF47899.1 - 0.051 13.3 0.5 0.19 11.5 0.3 1.9 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Sec23_trunk PF04811.15 OWF47899.1 - 0.066 12.8 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Med11 PF10280.9 OWF47899.1 - 0.07 13.6 0.1 0.34 11.4 0.1 1.9 1 1 1 2 2 2 0 Mediator complex protein Syntaxin_2 PF14523.6 OWF47899.1 - 0.07 13.5 1.8 0.16 12.3 1.8 1.6 1 1 0 1 1 1 0 Syntaxin-like protein PTPA PF03095.15 OWF47899.1 - 0.079 12.4 0.4 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein RRF PF01765.19 OWF47899.1 - 0.081 12.9 1.0 0.17 11.8 0.7 1.6 1 1 1 2 2 2 0 Ribosome recycling factor OrfB_IS605 PF01385.19 OWF47899.1 - 0.086 13.1 0.2 0.26 11.5 0.1 1.7 1 1 1 2 2 2 0 Probable transposase Med21 PF11221.8 OWF47899.1 - 0.088 13.1 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Focal_AT PF03623.13 OWF47899.1 - 0.11 12.5 0.1 0.37 10.8 0.1 1.9 1 1 0 1 1 1 0 Focal adhesion targeting region ArfGap PF01412.18 OWF47900.1 - 2.2e-25 89.0 0.1 3.6e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GST_N PF02798.20 OWF47901.1 - 2.1e-12 47.2 0.0 5.1e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF47901.1 - 6.2e-12 45.8 0.1 1.4e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF47901.1 - 6.4e-09 36.0 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF47901.1 - 1.1e-08 35.1 0.0 3.1e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF47901.1 - 1.9e-05 24.8 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF47901.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF47901.1 - 0.029 15.1 0.0 0.26 12.0 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Sulfatase PF00884.23 OWF47902.1 - 1.1e-49 169.5 1.7 1.5e-49 169.1 1.7 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OWF47902.1 - 0.008 14.8 0.0 0.015 13.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 OWF47902.1 - 0.0088 15.7 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF47903.1 - 2.1e-68 231.0 1.0 2.9e-68 230.6 1.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF47903.1 - 5.2e-05 23.0 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OWF47903.1 - 0.013 16.3 0.2 0.041 14.6 0.2 1.8 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.17 OWF47903.1 - 0.046 12.3 0.0 0.063 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF229) Trypsin_2 PF13365.6 OWF47904.1 - 1.4e-08 35.7 0.0 2.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF47904.1 - 0.006 16.4 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin TatD_DNase PF01026.21 OWF47905.1 - 1.7e-23 83.4 0.0 2e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Radical_SAM_C PF16199.5 OWF47905.1 - 0.019 15.0 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Radical_SAM C-terminal domain Ammonium_transp PF00909.21 OWF47906.1 - 2e-94 316.5 27.9 2.4e-94 316.3 27.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family TraT PF05818.12 OWF47906.1 - 0.19 11.4 0.7 0.4 10.3 0.7 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1691 PF07950.11 OWF47906.1 - 0.46 11.2 0.0 0.46 11.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1691) Helicase_C PF00271.31 OWF47907.1 - 1.4e-14 54.4 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 OWF47907.1 - 0.0097 16.1 0.1 0.14 12.3 0.0 2.1 1 1 1 2 2 2 1 Helicase C-terminal domain BNIP3 PF06553.12 OWF47908.1 - 0.037 13.7 0.7 0.055 13.1 0.0 1.7 2 0 0 2 2 2 0 BNIP3 Ig_3 PF13927.6 OWF47908.1 - 0.12 13.0 0.1 0.38 11.4 0.1 1.9 1 0 0 1 1 1 0 Immunoglobulin domain Trypsin_2 PF13365.6 OWF47909.1 - 0.03 15.2 0.1 0.11 13.4 0.1 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain Ank_2 PF12796.7 OWF47910.1 - 0.0032 18.0 0.0 0.0071 16.9 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF47910.1 - 0.026 15.1 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 OWF47910.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat MIB_HERC2 PF06701.13 OWF47911.1 - 2.8e-21 75.5 14.9 1.9e-12 47.2 4.1 3.3 3 0 0 3 3 3 2 Mib_herc2 WWE PF02825.20 OWF47911.1 - 2.2e-11 44.2 4.2 6.1e-11 42.7 0.5 3.0 3 0 0 3 3 3 1 WWE domain VWA_2 PF13519.6 OWF47911.1 - 4.4e-09 37.0 0.0 1.1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF47911.1 - 5.5e-07 30.0 0.0 1.5e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF47911.1 - 0.00089 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 OWF47912.1 - 1.4e-08 35.3 0.0 7.7e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain NHL PF01436.21 OWF47913.1 - 2.3e-24 84.1 7.8 1.7e-06 27.7 0.1 5.7 5 0 0 5 5 5 5 NHL repeat SGL PF08450.12 OWF47913.1 - 0.071 12.7 0.1 2.1 7.8 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region HscB_4_cys PF18256.1 OWF47913.1 - 0.19 11.5 0.4 18 5.2 0.2 3.2 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Perilipin PF03036.16 OWF47914.1 - 9.7e-05 21.6 0.3 0.025 13.6 0.0 2.6 1 1 1 2 2 2 2 Perilipin family Period_C PF12114.8 OWF47915.1 - 0.025 14.2 7.3 0.055 13.0 7.3 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MAM PF00629.23 OWF47916.1 - 2.3e-89 297.4 1.2 1.3e-26 93.5 0.2 4.4 4 0 0 4 4 4 4 MAM domain, meprin/A5/mu DDA1 PF10172.9 OWF47917.1 - 1.3e-29 102.2 1.4 1.5e-29 102.0 0.1 1.7 2 0 0 2 2 2 1 Det1 complexing ubiquitin ligase PCI PF01399.27 OWF47918.1 - 1.4e-24 86.6 5.1 1.6e-24 86.4 1.7 2.5 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 OWF47918.1 - 1.6e-05 24.6 4.4 1.5 9.0 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF47918.1 - 0.0011 18.9 2.9 5.5 7.4 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF47918.1 - 0.0021 17.8 7.0 1.1 9.2 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF4704 PF15787.5 OWF47918.1 - 0.0056 15.9 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) TPR_8 PF13181.6 OWF47918.1 - 3.7 8.0 7.3 37 4.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat adh_short PF00106.25 OWF47920.1 - 5.9e-41 140.1 0.9 1.1e-40 139.2 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF47920.1 - 3.1e-33 115.3 0.2 5e-33 114.6 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OWF47920.1 - 5.9e-33 113.1 0.0 1.4e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SCP2 PF02036.17 OWF47920.1 - 1.6e-22 79.9 0.3 9.6e-22 77.4 0.3 2.2 2 0 0 2 2 2 1 SCP-2 sterol transfer family KR PF08659.10 OWF47920.1 - 1.1e-12 48.2 0.3 1.9e-12 47.4 0.3 1.3 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 OWF47920.1 - 1.6e-08 34.8 0.0 6.2e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 OWF47920.1 - 0.016 15.4 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal UPF0556 PF10572.9 OWF47921.1 - 2.9e-15 56.1 0.0 3.5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 Rhabdo_matrix PF03397.14 OWF47921.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus matrix protein zf-C3HC4_2 PF13923.6 OWF47922.1 - 8.9e-10 38.3 14.9 3.6e-09 36.3 14.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF47922.1 - 1.4e-08 34.5 13.0 1.4e-08 34.5 13.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF47922.1 - 4.3e-08 32.9 15.5 4.3e-08 32.9 15.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF47922.1 - 3.8e-07 30.0 5.4 3.8e-07 30.0 5.4 2.5 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF47922.1 - 4e-07 30.2 14.4 4e-07 30.2 14.4 2.6 3 0 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 OWF47922.1 - 2.4e-05 24.1 10.9 2.4e-05 24.1 10.9 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OWF47922.1 - 6.4e-05 23.0 12.1 6.4e-05 23.0 12.1 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OWF47922.1 - 0.00016 21.5 6.9 0.0005 19.9 6.9 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OWF47922.1 - 0.00017 21.8 13.6 0.0012 19.1 13.6 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF47922.1 - 0.00021 21.2 14.4 0.00021 21.2 14.4 2.9 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 OWF47922.1 - 0.00029 21.0 0.0 0.00083 19.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain DUF5063 PF16702.5 OWF47922.1 - 0.0053 17.2 0.8 0.011 16.2 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5063) Erf4 PF10256.9 OWF47922.1 - 0.041 14.0 1.6 0.078 13.1 0.1 2.2 2 1 1 3 3 2 0 Golgin subfamily A member 7/ERF4 family zf-RING_11 PF17123.5 OWF47922.1 - 0.045 13.5 7.7 0.044 13.5 5.0 2.4 2 0 0 2 2 2 0 RING-like zinc finger DUF87 PF01935.17 OWF47922.1 - 0.15 12.1 1.5 0.29 11.2 1.5 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain YlqD PF11068.8 OWF47922.1 - 0.18 12.1 3.6 0.57 10.6 3.6 1.8 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.15 OWF47922.1 - 0.23 11.0 2.4 0.33 10.5 2.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 OWF47922.1 - 0.28 11.8 2.8 0.69 10.5 2.8 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 OWF47922.1 - 1.1 9.3 4.5 3.8 7.5 0.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 OWF47922.1 - 3.8 6.8 4.7 9.9 5.4 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ECH_2 PF16113.5 OWF47922.1 - 8.1 5.8 6.5 12 5.3 6.5 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Lipocalin_2 PF08212.12 OWF47923.1 - 1.7e-09 37.8 0.1 4.1e-09 36.5 0.1 1.7 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF47923.1 - 1.3e-06 28.7 0.1 2.3e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF47923.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Triabin LIP PF03583.14 OWF47923.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Lipocalin PF00061.23 OWF47924.1 - 0.11 12.7 0.4 0.23 11.6 0.4 1.6 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Poxvirus_B22R_C PF13168.6 OWF47925.1 - 0.0004 19.9 7.4 0.98 8.9 0.1 4.6 1 1 7 8 8 8 4 Poxvirus B22R protein C-terminal Kelch_4 PF13418.6 OWF47925.1 - 0.045 13.8 6.8 1e+02 3.0 0.0 6.6 6 2 2 8 8 8 0 Galactose oxidase, central domain Nuc_deoxyrib_tr PF05014.15 OWF47925.1 - 0.051 13.6 3.3 7.2 6.6 0.1 3.8 1 1 4 5 5 5 0 Nucleoside 2-deoxyribosyltransferase Stn1_C PF12659.7 OWF47925.1 - 0.069 13.1 0.5 31 4.5 0.0 3.2 1 1 3 4 4 4 0 Telomere capping C-terminal wHTH Zn_Tnp_IS91 PF14319.6 OWF47925.1 - 0.074 13.1 6.1 0.74 9.9 0.7 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain PPARgamma_N PF12577.8 OWF47925.1 - 0.24 12.1 19.7 21 5.8 0.3 5.8 1 1 2 3 3 3 0 PPAR gamma N-terminal region Herpes_UL32 PF06070.11 OWF47925.1 - 6.9 4.3 11.1 5.7 4.6 2.4 2.2 1 1 1 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 DUF615 PF04751.14 OWF47925.1 - 8.6 6.3 12.3 86 3.1 6.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF615) Poxvirus_B22R_C PF13168.6 OWF47926.1 - 0.033 13.7 1.7 6.1 6.3 0.2 2.3 1 1 1 2 2 2 0 Poxvirus B22R protein C-terminal C5-epim_C PF06662.13 OWF47926.1 - 0.098 12.2 0.3 0.11 12.0 0.3 1.1 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus PPARgamma_N PF12577.8 OWF47926.1 - 0.13 13.0 9.4 6.3 7.5 1.1 3.4 1 1 3 4 4 4 0 PPAR gamma N-terminal region PPARgamma_N PF12577.8 OWF47927.1 - 0.0023 18.5 6.1 5 7.8 0.1 3.2 1 1 3 4 4 4 3 PPAR gamma N-terminal region Poxvirus_B22R_C PF13168.6 OWF47927.1 - 0.0037 16.8 0.5 0.82 9.1 0.1 2.2 1 1 1 2 2 2 2 Poxvirus B22R protein C-terminal Cadherin_C PF01049.17 OWF47927.1 - 0.018 15.4 1.5 0.23 11.8 1.5 3.1 1 1 0 1 1 1 0 Cadherin cytoplasmic region CENP-Q PF13094.6 OWF47928.1 - 0.2 11.8 1.1 0.55 10.4 1.1 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2706 PF10913.8 OWF47928.1 - 0.45 10.4 2.1 0.6 10.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) Na_Ca_ex PF01699.24 OWF47929.1 - 6.7e-48 162.5 26.5 2.6e-24 85.9 7.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 OWF47929.1 - 4.7e-31 106.9 3.2 6.6e-14 51.9 0.6 3.8 4 0 0 4 4 4 2 Calx-beta domain Pkinase PF00069.25 OWF47931.1 - 6.3e-70 235.5 0.3 4.6e-68 229.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF47931.1 - 7.1e-27 94.3 0.0 1.5e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF47931.1 - 0.0023 17.3 0.2 0.0045 16.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF47931.1 - 0.14 12.1 0.2 0.32 10.9 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ribonuc_P_40 PF08584.11 OWF47931.1 - 0.35 10.1 0.0 0.35 10.1 0.0 3.0 2 2 1 3 3 3 0 Ribonuclease P 40kDa (Rpp40) subunit Iso_dh PF00180.20 OWF47932.1 - 1.4e-97 327.0 0.0 1.8e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 OWF47932.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA HSCB_C PF07743.13 OWF47933.1 - 1.4e-20 73.6 1.9 1.6e-20 73.3 0.5 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OWF47933.1 - 3e-06 27.3 2.5 5.1e-06 26.5 0.8 2.2 2 0 0 2 2 2 1 DnaJ domain STELLO PF03385.17 OWF47933.1 - 0.055 12.3 0.2 0.096 11.5 0.2 1.3 1 0 0 1 1 1 0 STELLO glycosyltransferases CTNNB1_binding PF08347.11 OWF47933.1 - 0.069 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding bZIP_1 PF00170.21 OWF47934.1 - 2e-13 50.2 14.5 4.8e-13 49.0 14.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF47934.1 - 6.6e-08 32.5 8.2 6.6e-08 32.5 8.2 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 OWF47934.1 - 5.5e-07 30.0 8.8 1.3e-06 28.8 8.8 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 OWF47934.1 - 0.0032 17.9 2.8 0.0032 17.9 2.8 2.0 2 0 0 2 2 2 1 Cell division protein ZapB DUF2207 PF09972.9 OWF47934.1 - 0.0089 14.8 0.8 0.016 14.0 0.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) HALZ PF02183.18 OWF47934.1 - 0.036 14.3 2.2 0.12 12.6 2.2 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF639 PF04842.12 OWF47934.1 - 0.056 12.8 0.5 0.098 12.1 0.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) SOGA PF11365.8 OWF47934.1 - 0.14 13.3 7.2 0.45 11.7 7.2 1.9 1 0 0 1 1 1 0 Protein SOGA M PF02370.16 OWF47934.1 - 2.8 8.8 6.4 19 6.2 6.4 2.6 1 0 0 1 1 1 0 M protein repeat BST2 PF16716.5 OWF47934.1 - 3 8.5 10.6 0.37 11.4 5.4 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 OWF47934.1 - 4.3 7.1 14.4 0.066 13.0 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4404 PF14357.6 OWF47934.1 - 6.7 7.4 10.8 0.63 10.7 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Nrap_D5 PF17406.2 OWF47935.1 - 2.4e-48 164.0 0.5 9.2e-48 162.1 0.2 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 OWF47935.1 - 3e-46 157.5 0.0 5.3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 OWF47935.1 - 3.6e-42 144.2 0.0 6.8e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 OWF47935.1 - 3.7e-41 140.7 0.1 8.1e-41 139.6 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 OWF47935.1 - 2.2e-37 128.2 0.1 6.8e-35 120.1 0.0 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 OWF47935.1 - 5.2e-29 101.2 0.0 1.1e-28 100.1 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 SelP_N PF04592.14 OWF47935.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF758 PF05527.11 OWF47936.1 - 4.5e-67 225.5 7.1 5.1e-67 225.4 7.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Pico_P2B PF01552.17 OWF47936.1 - 0.097 12.8 0.5 0.36 11.0 0.3 1.9 1 1 1 2 2 2 0 Picornavirus 2B protein Ribosomal_L12 PF00542.19 OWF47936.1 - 0.16 12.3 1.6 0.4 11.1 0.4 2.4 3 1 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain Ribosomal_S6e PF01092.19 OWF47937.1 - 1.1e-61 206.3 0.5 1.8e-61 205.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e BRCT_3 PF18428.1 OWF47938.1 - 6.2e-27 93.6 0.3 3.7e-26 91.2 0.2 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain 53-BP1_Tudor PF09038.10 OWF47938.1 - 1.8e-11 44.0 0.0 4.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor BRCT PF00533.26 OWF47938.1 - 1.2e-09 38.4 0.1 0.0022 18.3 0.1 3.6 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain Tudor_2 PF18104.1 OWF47938.1 - 4.4e-08 32.7 0.0 2.1e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 OWF47938.1 - 7.2e-08 32.0 0.6 5.2e-07 29.3 0.3 2.5 3 0 0 3 3 3 1 Histone methyltransferase Tudor domain 1 BRCT_2 PF16589.5 OWF47938.1 - 2e-07 31.3 0.2 8e-05 23.0 0.0 3.3 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Tudor_3 PF18115.1 OWF47938.1 - 7.4e-07 28.9 0.1 1.9e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 OWF47938.1 - 9.5e-07 28.9 0.0 3.4e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) RTT107_BRCT_5 PF16770.5 OWF47938.1 - 0.0031 17.4 0.1 0.038 13.9 0.0 2.7 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain DUF4772 PF15997.5 OWF47938.1 - 0.0062 17.1 0.0 0.19 12.3 0.0 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4772) PAP_assoc PF03828.19 OWF47939.1 - 1.1e-12 47.9 0.2 3.7e-12 46.3 0.2 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 OWF47939.1 - 0.072 13.2 0.0 0.38 10.9 0.0 2.2 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 OWF47939.1 - 0.095 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 OWF47939.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase NT domain IKI3 PF04762.12 OWF47940.1 - 6.6e-287 954.4 0.0 8.2e-287 954.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family nec1 PF10379.9 OWF47940.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Virulence protein nec1 AHD PF17793.1 OWF47940.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Bap31_Bap29_C PF18035.1 OWF47940.1 - 0.22 11.6 1.9 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain TPR_2 PF07719.17 OWF47940.1 - 5 7.5 5.0 3.9 7.8 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fibrinogen_BP PF08017.11 OWF47941.1 - 2.5e-05 22.9 0.0 3.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein DUF445 PF04286.12 OWF47941.1 - 0.0035 17.2 9.5 0.0047 16.8 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) GlutR_dimer PF00745.20 OWF47941.1 - 0.7 10.4 15.0 1.8e+04 -5.4 15.0 4.6 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain ABC_membrane_2 PF06472.15 OWF47941.1 - 1.5 8.2 10.4 4.2 6.7 3.2 2.7 1 1 2 3 3 3 0 ABC transporter transmembrane region 2 HI0933_like PF03486.14 OWF47941.1 - 1.6 7.3 22.7 2.6 6.7 7.0 2.3 1 1 1 2 2 2 0 HI0933-like protein LPD14 PF18827.1 OWF47941.1 - 2.2 8.5 23.2 18 5.6 3.5 3.9 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 14 I-set PF07679.16 OWF47942.1 - 4.4e-26 90.8 6.4 1.4e-10 41.1 0.2 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF47942.1 - 1.8e-25 89.3 14.3 2.8e-09 37.4 0.6 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF47942.1 - 9.1e-18 64.4 9.6 8.4e-05 22.7 0.9 5.0 3 2 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 OWF47942.1 - 1.7e-15 57.0 14.0 0.00023 21.2 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF47942.1 - 2.1e-15 56.8 16.5 7.9e-05 22.9 2.6 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Receptor_2B4 PF11465.8 OWF47942.1 - 5.5e-09 36.2 2.8 0.00024 21.3 0.1 3.2 2 1 1 3 3 3 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 OWF47942.1 - 3.8e-07 30.1 0.8 0.19 11.8 0.0 3.6 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 OWF47942.1 - 4.7e-07 29.3 0.3 0.045 13.3 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain RsgA_GTPase PF03193.16 OWF47942.1 - 2.3e-06 27.6 0.2 0.00032 20.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Ig_4 PF16680.5 OWF47942.1 - 9e-05 22.7 13.4 0.26 11.6 0.0 4.0 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain MMR_HSR1 PF01926.23 OWF47942.1 - 0.00011 22.3 0.0 0.00027 21.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ig_5 PF16681.5 OWF47942.1 - 0.00021 21.6 10.8 0.076 13.4 0.8 4.2 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ATP_bind_1 PF03029.17 OWF47942.1 - 0.01 15.6 0.8 0.56 9.9 0.4 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 OWF47942.1 - 0.015 15.4 0.1 0.059 13.4 0.1 2.1 1 1 0 1 1 1 0 Dynamin family BTD PF09270.10 OWF47943.1 - 4e-75 251.2 0.0 8.2e-75 250.2 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 OWF47943.1 - 1.9e-49 168.1 0.4 4.2e-49 167.1 0.4 1.6 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 OWF47943.1 - 0.0015 18.5 0.0 0.0046 17.0 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain MINDY_DUB PF04424.13 OWF47944.1 - 1.1e-37 128.6 0.1 2.2e-37 127.6 0.1 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase IHABP4_N PF16174.5 OWF47944.1 - 4.6 7.8 19.3 1.1 9.9 11.0 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal 7tm_2 PF00002.24 OWF47945.1 - 1.9e-11 43.7 28.2 3e-11 43.1 28.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 OWF47945.1 - 0.0016 18.8 16.3 0.033 14.6 3.9 3.3 2 0 0 2 2 2 2 Somatomedin B domain Cytochrom_C550 PF14495.6 OWF47945.1 - 0.19 11.4 0.6 0.4 10.4 0.2 1.7 2 0 0 2 2 2 0 Cytochrome c-550 domain DUF4064 PF13273.6 OWF47945.1 - 2.5 8.4 10.8 19 5.6 2.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) Neur_chan_LBD PF02931.23 OWF47946.1 - 9.6e-34 116.7 0.6 2.3e-33 115.4 0.6 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain CwfJ_C_1 PF04677.15 OWF47947.1 - 1.5e-37 128.1 0.1 2.9e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OWF47947.1 - 2.2e-15 57.3 0.0 4.5e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.28 OWF47947.1 - 0.047 14.2 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF4471 PF14740.6 OWF47948.1 - 5.4e-107 357.6 4.6 8.4e-107 356.9 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 OWF47948.1 - 4.2e-28 97.4 0.1 1.4e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) Goodbye PF17109.5 OWF47948.1 - 3 8.3 6.1 36 4.8 4.4 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain Defensin_big PF14862.6 OWF47949.1 - 1.7e-12 47.4 0.8 3.7e-12 46.4 0.8 1.6 1 1 0 1 1 1 1 Big defensin adh_short PF00106.25 OWF47950.1 - 3e-54 183.5 0.0 3.8e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF47950.1 - 2.7e-53 180.9 0.0 3.4e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF47950.1 - 1.4e-11 44.6 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF47950.1 - 0.0045 16.4 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OWF47950.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tenui_N PF05733.11 OWF47950.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein PH PF00169.29 OWF47951.1 - 1.8e-18 66.9 1.1 5.1e-18 65.5 1.1 1.8 1 0 0 1 1 1 1 PH domain WW PF00397.26 OWF47951.1 - 2.3e-13 50.0 0.2 4.8e-08 32.9 0.1 3.0 2 0 0 2 2 2 2 WW domain PH_11 PF15413.6 OWF47951.1 - 2.3e-06 28.0 5.2 2.2e-05 24.8 5.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OWF47951.1 - 1.6 9.2 3.8 3.4 8.0 0.9 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain LMBR1 PF04791.16 OWF47951.1 - 1.6 7.5 7.1 5.2 5.9 7.1 1.9 1 0 0 1 1 1 0 LMBR1-like membrane protein DENN PF02141.21 OWF47953.1 - 2.3e-43 148.3 5.6 4.9e-43 147.2 5.6 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OWF47953.1 - 1.7e-14 54.3 0.1 5.1e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OWF47953.1 - 1.1e-08 35.0 1.0 3e-08 33.5 1.0 1.8 1 0 0 1 1 1 1 dDENN domain DUF4015 PF13200.6 OWF47953.1 - 0.0079 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain Ribosomal_L27A PF00828.19 OWF47954.1 - 7.3e-25 88.1 0.0 9.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DDE_2 PF02914.15 OWF47954.1 - 0.025 14.3 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu transposase RTC4 PF14474.6 OWF47954.1 - 0.026 14.7 0.2 0.047 13.8 0.1 1.5 1 1 0 1 1 1 0 RTC4-like domain Acetyltransf_18 PF18014.1 OWF47955.1 - 2.3e-13 50.1 0.0 6.9e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF47955.1 - 2.8e-07 30.8 0.0 6.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF47955.1 - 1e-06 28.7 0.0 0.00036 20.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF47955.1 - 5.8e-06 26.5 0.0 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OWF47955.1 - 0.00032 20.8 0.0 0.032 14.3 0.0 3.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 OWF47955.1 - 0.0044 17.2 0.1 0.13 12.4 0.0 2.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain VCBS PF13517.6 OWF47957.1 - 9.9e-16 58.1 17.6 0.0028 18.2 1.3 5.8 6 0 0 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OWF47957.1 - 6.6e-07 29.3 29.2 0.022 14.9 2.9 5.5 5 0 0 5 5 5 4 FG-GAP repeat PQQ_2 PF13360.6 OWF47957.1 - 1.4e-05 24.8 1.0 0.0056 16.3 0.3 2.8 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OWF47957.1 - 0.002 18.0 10.4 0.014 15.3 0.3 4.7 5 0 0 5 5 5 1 PQQ enzyme repeat TcdB_toxin_midN PF12256.8 OWF47957.1 - 0.0023 17.4 1.4 5.3 6.4 0.0 3.9 3 1 1 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.32 OWF47957.1 - 0.35 10.5 7.5 4.6 7.0 0.1 4.1 4 0 0 4 4 4 0 EF hand EF-hand_5 PF13202.6 OWF47957.1 - 0.54 9.8 11.7 4.1 7.1 0.1 4.5 4 0 0 4 4 4 0 EF hand Glycogen_syn PF05693.13 OWF47958.1 - 0 1088.7 0.5 0 1088.4 0.5 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 OWF47958.1 - 9e-09 35.4 0.0 1.2e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OWF47958.1 - 1.3e-06 28.1 0.0 0.00029 20.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OWF47958.1 - 4.4e-05 23.9 0.0 0.012 16.1 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OWF47958.1 - 0.0014 18.7 0.1 0.0024 17.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF4532 PF15046.6 OWF47960.1 - 5.1e-31 107.9 6.1 9.5e-31 107.0 6.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4532) Syntaxin_2 PF14523.6 OWF47961.1 - 4.3e-21 75.2 8.9 1.9e-20 73.1 6.2 2.1 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 OWF47961.1 - 1.5e-18 66.5 0.8 4.8e-18 64.9 0.1 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 OWF47961.1 - 1.9e-05 24.4 14.8 0.00013 21.7 14.8 2.2 1 1 0 1 1 1 1 Syntaxin TMF_TATA_bd PF12325.8 OWF47961.1 - 0.00036 20.7 8.6 0.0022 18.2 1.8 2.5 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 OWF47961.1 - 0.0029 18.2 11.9 0.012 16.2 0.2 3.6 2 2 2 4 4 4 2 SlyX MCPsignal PF00015.21 OWF47961.1 - 0.0082 16.0 6.1 0.28 11.0 0.3 2.6 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DHR10 PF18595.1 OWF47961.1 - 0.012 15.6 3.2 0.012 15.6 3.2 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 OWF47961.1 - 0.021 14.9 7.1 0.27 11.3 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ApoLp-III PF07464.11 OWF47961.1 - 0.041 14.0 3.1 0.082 13.0 1.0 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cytochrom_C1 PF02167.15 OWF47961.1 - 0.1 12.3 0.2 0.23 11.1 0.2 1.6 1 1 0 1 1 1 0 Cytochrome C1 family Tropomyosin_1 PF12718.7 OWF47961.1 - 0.21 11.8 9.1 0.26 11.5 0.2 2.8 2 2 0 2 2 2 0 Tropomyosin like Gly_acyl_tr_N PF06021.11 OWF47961.1 - 0.24 11.5 2.3 0.38 10.8 1.8 1.5 1 1 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase DUF4366 PF14283.6 OWF47961.1 - 0.4 10.7 4.6 0.5 10.4 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) TMPIT PF07851.13 OWF47961.1 - 2.7 7.2 5.3 5.7 6.1 1.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein MCU PF04678.13 OWF47961.1 - 3.6 7.7 6.2 6.8 6.7 1.8 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CENP-H PF05837.12 OWF47961.1 - 7.9 6.9 9.2 1 9.8 3.4 2.4 2 2 0 2 2 2 0 Centromere protein H (CENP-H) HIP1_clath_bdg PF16515.5 OWF47961.1 - 9.6 6.9 11.7 2.1 9.0 3.7 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-LITAF-like PF10601.9 OWF47962.1 - 6.8e-27 93.5 8.4 8.7e-27 93.2 8.4 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain SAM_1 PF00536.30 OWF47963.1 - 5e-27 94.1 0.5 3e-12 46.8 0.1 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF47963.1 - 1.3e-24 86.0 0.7 9.1e-11 41.7 0.1 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) NRN1 PF15056.6 OWF47963.1 - 1.3 9.2 5.0 4.8 7.3 1.1 3.2 2 0 0 2 2 2 0 Neuritin protein family DUF4253 PF14062.6 OWF47963.1 - 2 8.6 4.7 68 3.7 0.2 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4253) SLATT_5 PF18160.1 OWF47963.1 - 3.7 6.8 7.0 11 5.2 7.0 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 NOB1_Zn_bind PF08772.11 OWF47964.1 - 0.16 12.2 0.5 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like EF-hand_7 PF13499.6 OWF47965.1 - 3.5e-08 33.8 3.7 3.5e-08 33.8 3.7 3.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF47965.1 - 1.9e-06 27.0 1.6 0.008 15.7 0.7 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF47965.1 - 5.4e-06 25.9 3.2 0.0016 18.2 1.6 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OWF47965.1 - 0.0062 16.4 1.8 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair COMM_domain PF07258.14 OWF47966.1 - 9e-25 86.6 0.3 2e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 COMM domain SEFIR PF08357.11 OWF47967.1 - 7.4e-18 65.3 0.1 1.2e-17 64.6 0.1 1.3 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 OWF47967.1 - 5.7e-09 36.6 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain THEG4 PF15834.5 OWF47967.1 - 0.013 15.6 0.2 0.038 14.0 0.1 1.8 1 1 0 1 1 1 0 Testis highly expressed protein 4 ELO PF01151.18 OWF47968.1 - 1e-56 192.3 20.0 1.2e-56 192.1 20.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 OWF47969.1 - 7.9e-64 215.6 24.9 1e-63 215.2 24.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Thioredoxin PF00085.20 OWF47970.1 - 4.3e-14 52.3 0.0 9.2e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 OWF47970.1 - 0.00062 19.7 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 OWF47970.1 - 0.0044 16.9 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OWF47970.1 - 0.0088 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OWF47970.1 - 0.021 15.3 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain ELO PF01151.18 OWF47971.1 - 1.6e-40 139.2 22.6 3.7e-40 138.0 22.6 1.5 1 1 0 1 1 1 1 GNS1/SUR4 family Uso1_p115_head PF04869.14 OWF47972.1 - 2.8e-60 204.1 4.1 7.5e-60 202.7 0.6 2.6 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 OWF47972.1 - 5.9e-30 103.0 4.4 5.9e-30 103.0 4.4 3.2 5 0 0 5 5 5 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 OWF47972.1 - 5e-12 46.3 33.4 5e-12 46.3 33.4 3.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT_2 PF13646.6 OWF47972.1 - 0.0058 17.0 0.0 0.11 12.9 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats DDE_Tnp_IS66 PF03050.14 OWF47972.1 - 0.48 9.8 12.2 0.29 10.5 3.0 2.6 2 1 0 2 2 2 0 Transposase IS66 family UPF0242 PF06785.11 OWF47972.1 - 0.73 9.9 51.8 0.023 14.8 9.9 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OWF47972.1 - 1 8.2 54.1 0.38 9.6 14.9 3.9 1 1 3 4 4 4 0 Spc7 kinetochore protein Yip1 PF04893.17 OWF47972.1 - 2 8.1 3.8 3.5 7.3 3.8 1.3 1 0 0 1 1 1 0 Yip1 domain CALCOCO1 PF07888.11 OWF47972.1 - 3 6.6 47.8 0.03 13.2 27.8 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 OWF47972.1 - 6.8 7.1 42.5 3.5 8.0 14.3 2.7 1 1 0 2 2 2 0 Fez1 Mre11_DNA_bind PF04152.14 OWF47973.1 - 1.6e-51 175.0 3.8 2.4e-51 174.4 0.0 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OWF47973.1 - 1.4e-14 55.1 1.9 2.2e-14 54.5 1.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF47973.1 - 3e-06 27.5 0.0 2.2e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4392 PF14336.6 OWF47973.1 - 0.24 10.8 1.2 0.46 9.9 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF4586 PF15239.6 OWF47974.1 - 1.9e-102 343.5 12.7 2.2e-102 343.3 12.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) USP7_ICP0_bdg PF12436.8 OWF47975.1 - 1.7e-76 256.7 0.0 4.5e-76 255.3 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OWF47975.1 - 9.3e-71 237.8 3.1 2.8e-70 236.2 1.6 2.5 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OWF47975.1 - 1.8e-49 168.5 1.2 4.1e-49 167.4 1.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF47975.1 - 1.3e-19 71.0 2.7 1.9e-19 70.4 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OWF47975.1 - 2.2e-19 69.6 3.5 1.4e-18 67.1 0.8 3.3 3 0 0 3 3 3 1 MATH domain Peptidase_C98 PF15499.6 OWF47975.1 - 0.029 13.8 0.5 7.3 6.0 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4588 PF15251.6 OWF47976.1 - 7.7e-78 261.7 0.2 8.9e-78 261.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) SPRY PF00622.28 OWF47977.1 - 1.4e-22 80.0 0.7 2.7e-22 79.1 0.1 1.7 2 0 0 2 2 2 1 SPRY domain SOCS_box PF07525.16 OWF47977.1 - 0.028 14.8 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 SOCS box ABC2_membrane_3 PF12698.7 OWF47978.1 - 1.4e-64 218.4 38.4 2.2e-40 138.9 21.8 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 OWF47978.1 - 3.2e-53 179.9 0.0 3.8e-26 92.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OWF47978.1 - 2.2e-22 80.3 2.6 1.1e-08 35.2 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF47978.1 - 0.00042 20.9 2.2 0.041 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OWF47978.1 - 0.0011 18.5 0.2 12 5.2 0.0 4.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OWF47978.1 - 0.0013 18.5 0.0 0.57 9.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 OWF47978.1 - 0.0097 15.6 0.5 0.29 10.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OWF47978.1 - 0.016 15.4 0.0 17 5.7 0.0 3.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 OWF47978.1 - 0.022 14.5 0.4 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF47978.1 - 0.051 13.5 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 OWF47978.1 - 0.061 13.2 0.0 4.4 7.2 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain SRP54 PF00448.22 OWF47978.1 - 0.069 12.8 5.1 1.5 8.4 0.6 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4162 PF13732.6 OWF47978.1 - 0.071 13.8 0.0 2.7 8.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_29 PF13555.6 OWF47978.1 - 0.15 11.8 3.6 0.6 9.9 0.5 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OWF47978.1 - 0.16 12.3 1.6 2.4 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 OWF47978.1 - 0.28 11.0 4.5 0.27 11.0 0.5 2.4 3 0 0 3 3 3 0 MukB N-terminal ParA PF10609.9 OWF47979.1 - 9.7e-100 333.1 0.0 1.1e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OWF47979.1 - 4.3e-11 43.0 0.0 5.2e-09 36.2 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OWF47979.1 - 1.2e-08 35.1 0.5 6.6e-08 32.7 0.5 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 OWF47979.1 - 1.6e-08 34.2 0.0 4.1e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OWF47979.1 - 2.7e-06 26.8 0.2 1.7e-05 24.2 0.0 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 OWF47979.1 - 9e-05 22.4 0.5 0.0048 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OWF47979.1 - 0.0007 19.5 0.0 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase MeaB PF03308.16 OWF47979.1 - 0.00088 18.3 0.1 0.0013 17.8 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 OWF47979.1 - 0.0018 17.7 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 OWF47979.1 - 0.0038 16.4 0.2 0.007 15.6 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 OWF47979.1 - 0.011 15.3 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OWF47979.1 - 0.031 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CBP_BcsQ PF06564.12 OWF47979.1 - 0.033 13.7 0.1 0.067 12.7 0.1 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 OWF47979.1 - 0.036 14.0 0.5 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 OWF47979.1 - 0.07 12.8 0.2 0.16 11.5 0.2 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OWF47979.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 OWF47979.1 - 0.11 12.2 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Pox_A3L PF05288.11 OWF47979.1 - 0.14 12.2 0.3 0.64 10.1 0.0 2.2 3 0 0 3 3 3 0 Poxvirus A3L Protein NTPase_1 PF03266.15 OWF47979.1 - 0.25 11.3 0.6 0.57 10.1 0.6 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 OWF47979.1 - 0.25 11.1 0.4 0.5 10.1 0.3 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF47979.1 - 0.26 11.2 0.6 0.5 10.3 0.6 1.4 1 0 0 1 1 1 0 NACHT domain RQC PF09382.10 OWF47980.1 - 0.026 14.3 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 RQC domain ERCC4 PF02732.15 OWF47981.1 - 1.3e-11 44.9 2.7 1.6e-11 44.7 0.1 2.2 2 0 0 2 2 2 1 ERCC4 domain Pex26 PF07163.12 OWF47981.1 - 0.55 9.5 3.4 1.2 8.4 3.4 1.5 1 0 0 1 1 1 0 Pex26 protein Collectrin PF16959.5 OWF47981.1 - 2.1 8.1 8.1 0.17 11.7 1.1 2.6 3 0 0 3 3 3 0 Renal amino acid transporter Ribosomal_L27 PF01016.19 OWF47982.1 - 4.7e-14 52.2 0.2 8e-14 51.4 0.1 1.4 1 1 0 1 1 1 1 Ribosomal L27 protein Biotin_lipoyl_2 PF13533.6 OWF47982.1 - 0.041 13.7 0.4 0.25 11.2 0.2 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like LRR_8 PF13855.6 OWF47983.1 - 1.1e-10 41.1 16.2 0.01 15.6 0.6 5.6 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OWF47983.1 - 2.2e-07 31.1 16.7 0.001 19.4 0.3 5.8 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF47983.1 - 5.7e-07 29.1 10.3 1.5 9.0 0.0 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 OWF47983.1 - 0.29 11.8 17.1 54 4.9 0.1 7.2 6 2 2 8 8 8 0 Leucine Rich Repeat Ribosomal_S7 PF00177.21 OWF47984.1 - 8.3e-29 100.2 0.7 1.1e-28 99.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Vps4_C PF09336.10 OWF47984.1 - 0.056 13.4 0.0 29 4.8 0.0 3.3 3 1 0 3 3 3 0 Vps4 C terminal oligomerisation domain Death PF00531.22 OWF47985.1 - 0.00012 22.2 0.4 0.00021 21.4 0.4 1.3 1 0 0 1 1 1 1 Death domain EF-hand_1 PF00036.32 OWF47985.1 - 0.00042 19.7 1.4 0.0028 17.1 0.5 2.7 2 0 0 2 2 2 1 EF hand Methyltrn_RNA_3 PF02598.17 OWF47985.1 - 0.0021 17.6 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase EF-hand_6 PF13405.6 OWF47985.1 - 0.0034 17.2 1.9 0.022 14.7 0.1 3.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 OWF47985.1 - 0.0034 17.8 0.9 0.087 13.3 0.2 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF47985.1 - 0.0072 16.2 1.7 0.18 11.7 0.3 2.8 3 1 0 3 3 3 1 EF-hand domain pair Herpes_LMP1 PF05297.11 OWF47986.1 - 0.02 14.1 42.6 0.23 10.6 12.5 3.7 1 1 1 3 3 3 0 Herpesvirus latent membrane protein 1 (LMP1) YjcB PF15940.5 OWF47986.1 - 0.58 10.4 31.7 7.4 6.8 1.1 6.5 1 1 7 8 8 8 0 Family of unknown function Cation_ATPase_C PF00689.21 OWF47987.1 - 2.4e-07 30.7 7.2 2.4e-07 30.7 7.2 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OWF47987.1 - 0.0014 18.2 0.0 0.0014 18.2 0.0 3.3 4 0 0 4 4 4 1 E1-E2 ATPase PI-PLC-X PF00388.19 OWF47987.1 - 0.016 14.8 0.0 0.043 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF5074 PF16819.5 OWF47988.1 - 1.7e-13 50.6 59.0 5.2 7.2 0.2 19.5 1 1 19 20 20 20 20 Domain of unknown function (DUF5074) BAH PF01426.18 OWF47989.1 - 2.2e-10 40.4 0.0 5.7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 BAH domain Tudor_3 PF18115.1 OWF47989.1 - 0.00013 21.8 0.0 0.00035 20.3 0.0 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain PBP-Tp47_a PF14889.6 OWF47989.1 - 1.3 8.6 6.4 4.2 7.0 6.4 1.9 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Evr1_Alr PF04777.13 OWF47992.1 - 1.5e-30 105.6 5.4 1.7e-30 105.4 3.0 1.9 2 0 0 2 2 2 1 Erv1 / Alr family FAD_SOX PF18371.1 OWF47992.1 - 0.12 12.8 0.1 1.9 8.9 0.0 2.4 1 1 2 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase p450 PF00067.22 OWF47993.1 - 7.4e-92 308.5 0.1 9.6e-92 308.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 UPF0149 PF03695.13 OWF47993.1 - 0.054 13.8 0.1 0.22 11.8 0.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0149) Metallophos PF00149.28 OWF47994.1 - 2.5e-38 132.7 0.3 3.2e-38 132.3 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OWF47994.1 - 4.3e-18 65.5 1.4 7.1e-18 64.8 1.4 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF903 PF06004.12 OWF47994.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) DNA_binding_1 PF01035.20 OWF47995.1 - 7.1e-24 83.7 0.0 4.3e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain UCH PF00443.29 OWF47996.1 - 1.9e-56 191.5 1.6 3.4e-56 190.6 1.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF47996.1 - 7.9e-15 55.3 6.9 4.3e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Zn_Tnp_IS1595 PF12760.7 OWF47996.1 - 0.044 13.8 1.6 5.7 7.0 0.0 2.6 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 OWF47996.1 - 0.28 10.6 3.2 8.8 5.9 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Sial-lect-inser PF09264.10 OWF47997.1 - 0.0078 16.0 0.5 0.22 11.3 0.1 2.7 1 1 2 3 3 3 1 Vibrio cholerae sialidase, lectin insertion HTH_46 PF15977.5 OWF47997.1 - 0.0092 16.0 0.6 9.6 6.3 0.2 3.9 1 1 1 2 2 2 2 Winged helix-turn-helix DNA binding E3_UbLigase_EDD PF11547.8 OWF47997.1 - 1.4 8.6 34.5 79 3.1 1.6 11.0 1 1 7 8 8 8 0 E3 ubiquitin ligase EDD IL3 PF02059.15 OWF47997.1 - 5.8 7.0 12.9 34 4.5 1.7 3.9 1 1 2 3 3 3 0 Interleukin-3 Arf PF00025.21 OWF47999.1 - 2e-20 73.0 0.1 2.6e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF47999.1 - 0.00028 20.8 0.0 0.082 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OWF47999.1 - 0.0035 17.7 0.1 0.0039 17.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF47999.1 - 0.0039 17.5 0.1 0.014 15.6 0.1 2.1 1 1 1 2 2 2 1 AAA domain Roc PF08477.13 OWF47999.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OWF47999.1 - 0.02 14.4 0.2 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_2 PF07724.14 OWF47999.1 - 0.024 14.8 0.0 0.031 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OWF47999.1 - 0.029 14.3 0.1 0.039 13.9 0.1 1.6 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 OWF47999.1 - 0.033 14.6 0.1 0.049 14.0 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OWF47999.1 - 0.046 13.1 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 OWF47999.1 - 0.057 13.0 0.7 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 OWF47999.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 OWF47999.1 - 0.088 12.1 0.1 0.25 10.7 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AIMP2_LysRS_bd PF16780.5 OWF47999.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain AAA_33 PF13671.6 OWF47999.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OWF47999.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain VHS PF00790.19 OWF48000.1 - 1.8e-42 144.6 0.1 1.8e-42 144.6 0.1 2.5 2 0 0 2 2 2 1 VHS domain Hrs_helical PF12210.8 OWF48000.1 - 2e-39 134.0 7.7 2e-39 134.0 7.7 2.7 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 OWF48000.1 - 2.1e-17 63.0 10.9 4.5e-17 61.9 10.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OWF48000.1 - 0.0099 16.1 3.6 0.0099 16.1 3.6 2.9 3 0 0 3 3 3 1 FYVE-type zinc finger UIM PF02809.20 OWF48000.1 - 0.015 15.1 4.7 0.015 15.1 4.7 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif DZR PF12773.7 OWF48000.1 - 0.4 10.8 9.1 14 5.8 0.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 OWF48000.1 - 1.3 9.1 12.6 3.1 7.8 12.6 1.7 1 1 0 1 1 1 0 zinc-RING finger domain DUF4407 PF14362.6 OWF48000.1 - 4.5 6.5 16.8 0.25 10.6 10.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Kri1 PF05178.12 OWF48000.1 - 6.6 7.4 13.7 0.37 11.4 5.2 3.0 3 0 0 3 3 3 0 KRI1-like family zf-AN1 PF01428.16 OWF48000.1 - 8.4 6.7 12.3 16 5.7 12.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Chromo PF00385.24 OWF48001.1 - 2.6e-15 56.1 1.7 4.4e-15 55.3 1.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 OWF48001.1 - 0.0048 16.6 2.5 0.011 15.4 2.5 1.6 1 0 0 1 1 1 1 CBX family C-terminal motif Mtf2_C PF14061.6 OWF48001.1 - 0.017 15.3 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 G-alpha PF00503.20 OWF48002.1 - 6.5e-97 324.9 9.3 7.8e-97 324.6 9.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OWF48002.1 - 3.8e-14 52.5 1.6 1e-13 51.1 1.6 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF48002.1 - 2.8e-05 23.6 3.1 4.2e-05 23.0 3.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_assoc PF14363.6 OWF48002.1 - 0.052 13.9 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Roc PF08477.13 OWF48002.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.5 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MG1 PF17790.1 OWF48003.1 - 1.9e-06 28.2 0.4 9.7 6.7 0.1 5.0 1 1 5 6 6 6 2 Macroglobulin domain MG1 GTP_EFTU_D3 PF03143.17 OWF48003.1 - 0.00024 21.4 1.0 28 5.1 0.0 4.5 1 1 6 7 7 7 0 Elongation factor Tu C-terminal domain Big_3_5 PF16640.5 OWF48003.1 - 0.0022 18.1 26.2 2.6 8.3 1.4 5.1 1 1 4 5 5 5 4 Bacterial Ig-like domain (group 3) GlyL_C PF12524.8 OWF48003.1 - 0.0042 17.2 14.1 16 5.7 0.1 5.4 1 1 7 8 8 8 2 dsDNA virus glycoprotein L C terminal DUF3568 PF12092.8 OWF48003.1 - 0.043 13.9 7.0 5.7 7.0 1.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3568) PB1-F2 PF11986.8 OWF48003.1 - 0.94 9.7 14.9 24 5.2 0.4 5.0 1 1 7 8 8 8 0 Influenza A Proapoptotic protein DUF5334 PF17268.2 OWF48003.1 - 2.9 8.2 14.5 24 5.3 0.2 4.3 1 1 4 6 6 6 0 Family of unknown function (DUF5334) DUF1720 PF08226.11 OWF48003.1 - 7.7 7.0 18.2 1.8e+04 -4.9 18.2 3.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Zn_ribbon_17 PF17120.5 OWF48004.1 - 2.5e-10 39.8 16.3 2.5e-10 39.8 16.3 2.0 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 OWF48004.1 - 6.2e-10 39.5 16.6 0.00034 21.4 0.3 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 OWF48004.1 - 7.8e-06 26.1 9.0 7.8e-06 26.1 9.0 2.7 2 1 1 3 3 3 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 OWF48004.1 - 0.035 14.4 0.3 1.3 9.4 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RWD PF05773.22 OWF48004.1 - 0.077 13.3 0.5 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 RWD domain Ge1_WD40 PF16529.5 OWF48004.1 - 0.088 11.8 0.0 0.44 9.5 0.0 2.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Phage_min_tail PF05939.13 OWF48004.1 - 0.66 10.4 4.0 0.24 11.8 0.3 2.2 3 0 0 3 3 3 0 Phage minor tail protein zf-RING_2 PF13639.6 OWF48004.1 - 1.4 9.3 11.0 0.54 10.6 7.0 2.5 2 0 0 2 2 2 0 Ring finger domain DREV PF05219.12 OWF48006.1 - 1.8e-95 319.0 0.0 2.2e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 OWF48006.1 - 2.8e-07 30.5 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF48006.1 - 1.4e-06 29.0 0.0 4e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF48006.1 - 2.5e-05 24.8 0.0 5.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF48006.1 - 0.0013 19.4 0.0 0.0037 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 OWF48006.1 - 0.031 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 OWF48006.1 - 0.067 13.0 0.0 0.68 9.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain CheC PF04509.12 OWF48007.1 - 7.8e-07 28.9 0.0 10 6.1 0.0 6.1 6 0 0 6 6 6 1 CheC-like family OCRE PF17780.1 OWF48007.1 - 0.00071 19.6 10.3 39 4.4 0.0 7.5 9 0 0 9 9 9 0 OCRE domain DUF4350 PF14258.6 OWF48007.1 - 0.0086 16.5 4.7 26 5.3 0.0 6.1 2 2 5 7 7 7 0 Domain of unknown function (DUF4350) Phi-29_GP4 PF05464.11 OWF48007.1 - 0.011 16.0 5.1 9.8 6.5 0.1 5.7 5 2 3 8 8 8 0 Phi-29-like late genes activator (early protein GP4) AHSA1 PF08327.11 OWF48007.1 - 0.012 15.8 0.3 3.8 7.8 0.0 3.2 1 1 2 3 3 3 0 Activator of Hsp90 ATPase homolog 1-like protein Drf_FH1 PF06346.12 OWF48007.1 - 1.7 8.4 17.6 1.6 8.4 5.9 2.7 1 1 1 2 2 2 0 Formin Homology Region 1 Dict-STAT-coil PF09267.10 OWF48007.1 - 8.9 6.7 8.7 3e+02 1.8 0.0 5.5 6 1 0 7 7 7 0 Dictyostelium STAT, coiled coil CYTH PF01928.21 OWF48008.1 - 7.9e-20 71.5 0.1 1.2e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 CYTH domain Homeodomain PF00046.29 OWF48010.1 - 1e-61 204.6 22.3 3.8e-17 61.9 0.5 4.8 4 0 0 4 4 4 4 Homeodomain zf-C2H2 PF00096.26 OWF48010.1 - 6e-19 67.4 197.1 0.0081 16.6 0.7 26.1 27 0 0 27 27 27 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF48010.1 - 2e-17 62.4 164.5 0.13 13.2 0.8 25.1 25 0 0 25 25 24 13 C2H2-type zinc finger Homeobox_KN PF05920.11 OWF48010.1 - 1.9e-10 40.5 9.4 0.0063 16.4 0.1 5.4 5 0 0 5 5 5 4 Homeobox KN domain zf-Di19 PF05605.12 OWF48010.1 - 3.2e-08 33.7 7.1 3.2e-08 33.7 7.1 14.0 14 2 0 15 15 13 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 OWF48010.1 - 3.2e-05 23.6 4.9 0.0003 20.5 1.3 13.4 13 0 0 13 13 13 4 C2H2-type zinc-finger domain zf-met PF12874.7 OWF48010.1 - 0.00039 20.7 1.1 0.00039 20.7 1.1 17.0 19 0 0 19 19 18 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF48010.1 - 0.0045 16.9 0.9 0.0045 16.9 0.9 17.6 20 0 0 20 20 20 7 C2H2-type zinc finger Homez PF11569.8 OWF48010.1 - 0.034 13.6 0.9 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez MerR_1 PF13411.6 OWF48010.1 - 0.1 12.7 2.1 5.4 7.2 0.0 4.2 6 0 0 6 6 5 0 MerR HTH family regulatory protein Rad50_zn_hook PF04423.14 OWF48010.1 - 0.57 10.1 5.7 0.36 10.7 1.2 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif AKAP95 PF04988.12 OWF48010.1 - 4.8 7.4 72.9 0.48 10.6 0.0 13.1 15 1 1 16 16 14 0 A-kinase anchoring protein 95 (AKAP95) ATG16 PF08614.11 OWF48011.1 - 0.016 15.4 24.5 0.016 15.4 24.5 4.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PhnA PF03831.14 OWF48011.1 - 0.057 13.3 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 PhnA domain HOOK PF05622.12 OWF48011.1 - 0.41 8.7 63.9 0.46 8.6 26.6 2.4 1 1 1 2 2 2 0 HOOK protein MAD PF05557.13 OWF48011.1 - 4.7 5.5 70.4 0.027 12.8 36.6 2.5 1 1 1 2 2 2 0 Mitotic checkpoint protein MitMem_reg PF13012.6 OWF48012.1 - 1.3e-35 122.2 1.4 2.5e-35 121.3 1.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OWF48012.1 - 8.9e-33 112.8 1.8 1.5e-32 112.0 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SspB PF04386.13 OWF48012.1 - 0.011 15.6 2.6 0.025 14.5 1.2 2.2 3 0 0 3 3 3 0 Stringent starvation protein B RNA_pol_Rpc4 PF05132.14 OWF48012.1 - 0.013 15.9 2.3 0.02 15.3 2.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 OWF48012.1 - 0.015 15.1 4.9 0.025 14.3 4.9 1.3 1 0 0 1 1 1 0 Connexin Coilin_N PF15862.5 OWF48012.1 - 0.068 13.0 11.8 0.11 12.3 11.8 1.4 1 0 0 1 1 1 0 Coilin N-terminus CobT PF06213.12 OWF48012.1 - 0.12 11.8 6.3 0.17 11.2 6.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BT1 PF03092.16 OWF48012.1 - 0.35 9.0 1.3 0.53 8.5 1.3 1.2 1 0 0 1 1 1 0 BT1 family FAM176 PF14851.6 OWF48012.1 - 0.44 10.2 4.8 0.81 9.3 4.8 1.4 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 OWF48012.1 - 0.57 8.9 2.4 0.69 8.6 2.4 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 OWF48012.1 - 2 8.7 18.2 3.4 8.0 18.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.10 OWF48012.1 - 3.1 7.8 10.4 6.3 6.8 10.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF667 PF05018.13 OWF48014.1 - 8.5e-95 315.7 1.0 9.6e-95 315.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.25 OWF48015.1 - 2.4e-66 223.8 0.2 2.9e-66 223.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF48015.1 - 1.3e-17 64.0 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF48015.1 - 7.1e-07 29.4 0.2 1.2e-05 25.4 0.1 2.3 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OWF48015.1 - 0.00041 19.8 0.1 0.00071 19.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF48015.1 - 0.004 16.0 0.1 0.026 13.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 OWF48015.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 OWF48015.1 - 0.04 13.2 0.0 0.1 11.9 0.0 1.6 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 OWF48015.1 - 0.099 12.3 0.2 1.7 8.2 0.1 2.6 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Imm41 PF15592.6 OWF48015.1 - 1.2 9.5 4.8 6.7 7.1 0.4 2.5 1 1 1 2 2 2 0 Immunity protein 41 DUF4201 PF13870.6 OWF48016.1 - 1.2e-52 178.2 38.6 6.7e-52 175.8 29.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 OWF48016.1 - 0.0042 17.1 0.3 0.0042 17.1 0.3 5.2 6 1 1 7 7 7 1 TolA binding protein trimerisation FlaC_arch PF05377.11 OWF48016.1 - 0.032 14.6 1.4 0.032 14.6 1.4 5.7 5 2 2 7 7 7 0 Flagella accessory protein C (FlaC) 3-HAO PF06052.12 OWF48017.1 - 0.0058 16.3 9.0 10 5.7 1.1 4.5 1 1 3 4 4 4 4 3-hydroxyanthranilic acid dioxygenase SNF PF00209.18 OWF48018.1 - 6.3e-180 599.3 27.2 7.4e-180 599.1 27.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3522 PF12036.8 OWF48018.1 - 0.055 13.7 0.2 0.055 13.7 0.2 3.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3522) ATP-synt_J PF04911.12 OWF48018.1 - 0.74 9.4 4.4 0.36 10.4 0.8 2.4 2 0 0 2 2 2 0 ATP synthase j chain DUF4541 PF15074.6 OWF48019.1 - 1.1e-25 90.0 1.0 1.7e-25 89.4 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Ribosomal_L14e PF01929.17 OWF48020.1 - 5.7e-26 90.8 9.2 5.7e-26 90.8 9.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 OWF48020.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 KOW motif FAD-oxidase_C PF02913.19 OWF48021.1 - 7e-65 219.1 0.0 1e-64 218.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OWF48021.1 - 3.1e-35 120.9 0.0 5.3e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Laminin_G_2 PF02210.24 OWF48022.1 - 2.9e-19 69.9 0.0 3.8e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 OWF48022.1 - 1.3e-13 51.3 0.0 1.9e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain CIAPIN1 PF05093.13 OWF48023.1 - 1.4e-20 73.7 20.6 2.3e-18 66.5 2.9 2.9 2 2 1 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 PF08241.12 OWF48023.1 - 0.0052 17.4 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF48023.1 - 0.0091 15.8 0.1 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TPX2_importin PF12214.8 OWF48024.1 - 4.2e-28 98.6 90.2 5e-19 69.1 7.1 8.0 4 3 4 8 8 8 5 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 OWF48024.1 - 1.7e-09 37.8 13.3 1.7e-09 37.8 13.3 5.9 5 0 0 5 5 5 4 Targeting protein for Xklp2 (TPX2) PAC2 PF09754.9 OWF48025.1 - 2.7e-25 89.7 0.0 3.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 PAC2 family NACHT PF05729.12 OWF48025.1 - 0.019 14.9 0.2 0.043 13.7 0.1 1.5 2 0 0 2 2 2 0 NACHT domain FMO-like PF00743.19 OWF48026.1 - 4.3e-71 239.9 0.0 7.7e-52 176.4 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF48026.1 - 1.8e-13 50.4 0.0 2e-09 37.1 0.0 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF48026.1 - 1.9e-12 47.0 0.0 3.1e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF48026.1 - 8.3e-08 32.4 0.4 9.5e-07 29.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF48026.1 - 9.3e-08 32.0 0.3 0.0046 16.6 0.1 3.3 3 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OWF48026.1 - 8.2e-06 25.2 0.0 0.0016 17.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OWF48026.1 - 6.9e-05 22.9 0.3 0.0032 17.5 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 OWF48026.1 - 0.00087 18.6 0.2 0.033 13.4 0.0 2.4 2 1 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OWF48026.1 - 0.001 17.9 0.0 0.1 11.3 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 OWF48026.1 - 0.018 14.5 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 OWF48026.1 - 0.033 14.7 0.0 0.74 10.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF48026.1 - 0.13 11.3 0.1 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 OWF48027.1 - 3.9e-72 243.4 0.0 4.7e-53 180.4 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF48027.1 - 1.5e-14 54.0 0.3 2.2e-11 43.6 0.3 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF48027.1 - 3.4e-12 46.2 0.0 7.3e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF48027.1 - 2.8e-08 33.7 0.0 0.0026 17.4 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF48027.1 - 1.8e-07 31.2 0.0 4.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OWF48027.1 - 1.5e-05 24.3 0.1 0.0096 15.1 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OWF48027.1 - 3.2e-05 24.0 0.2 0.0011 19.0 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OWF48027.1 - 0.0058 15.9 0.0 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OWF48027.1 - 0.05 12.3 0.1 0.092 11.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein UPF0047 PF01894.17 OWF48027.1 - 0.054 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 Pyr_redox PF00070.27 OWF48027.1 - 0.17 12.5 0.1 4.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF48027.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Neur_chan_memb PF02932.16 OWF48029.1 - 2.1e-11 44.3 0.6 2.1e-11 44.3 0.6 2.0 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region PP1 PF07430.11 OWF48029.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Neur_chan_LBD PF02931.23 OWF48030.1 - 2.8e-37 128.3 7.5 1.1e-33 116.6 4.1 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48030.1 - 2.1e-10 41.1 0.7 3.2e-10 40.5 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF48031.1 - 4.7e-37 127.5 4.8 5e-37 127.4 4.8 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 OWF48032.1 - 1.1e-38 132.8 2.3 1.8e-38 132.1 2.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48032.1 - 2.3e-09 37.7 4.9 2.3e-09 37.7 4.9 1.9 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region MMS1_N PF10433.9 OWF48033.1 - 8.6e-181 601.8 0.0 1.7e-180 600.9 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OWF48033.1 - 2.2e-100 336.1 0.1 2e-98 329.7 0.0 2.8 3 0 0 3 3 3 2 CPSF A subunit region COG4 PF08318.12 OWF48034.1 - 1.5e-85 287.2 4.8 1.5e-85 287.2 4.8 2.0 2 0 0 2 2 2 1 COG4 transport protein Vps53_N PF04100.12 OWF48034.1 - 6.5e-06 25.4 4.6 6.5e-06 25.4 4.6 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal Kinesin PF00225.23 OWF48035.1 - 1.6e-107 359.3 2.9 1.6e-107 359.3 2.9 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF48035.1 - 6.4e-50 169.0 1.1 2.2e-49 167.2 0.1 2.5 2 0 0 2 2 2 1 Microtubule binding EzrA PF06160.12 OWF48035.1 - 0.00021 19.6 12.5 0.00021 19.6 12.5 3.4 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 OWF48035.1 - 0.0011 19.0 22.9 0.0011 19.0 22.9 5.7 5 1 0 5 5 5 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 OWF48035.1 - 0.0013 19.2 15.0 0.0013 19.2 15.0 6.0 4 2 2 6 6 6 1 Apg6 coiled-coil region BAF PF02961.14 OWF48035.1 - 0.058 13.8 0.1 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 Barrier to autointegration factor DUF2443 PF10398.9 OWF48035.1 - 0.35 10.9 8.4 0.33 11.0 0.2 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2443) DUF2937 PF11157.8 OWF48035.1 - 0.54 10.0 7.8 0.85 9.3 5.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF4407 PF14362.6 OWF48035.1 - 5 6.4 48.7 1.1 8.5 18.6 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 OWF48035.1 - 6.5 5.5 63.4 0.34 9.7 18.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF812) RVT_1 PF00078.27 OWF48036.1 - 4.9e-11 42.6 0.6 6e-11 42.3 0.6 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPA43_OB PF17875.1 OWF48036.1 - 0.066 13.8 0.0 0.097 13.3 0.0 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I MIP PF00230.20 OWF48037.1 - 1.6e-73 247.1 11.6 1.9e-73 246.9 11.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Rootletin PF15035.6 OWF48039.1 - 0.0043 17.1 2.6 0.0043 17.1 2.6 4.3 3 1 2 5 5 5 1 Ciliary rootlet component, centrosome cohesion Bcr-Abl_Oligo PF09036.10 OWF48039.1 - 0.068 13.2 7.0 0.45 10.5 0.7 4.1 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain RRF_GI PF12614.8 OWF48039.1 - 0.084 13.0 0.1 0.084 13.0 0.1 3.7 3 1 1 4 4 4 0 Ribosome recycling factor TED_complement PF07678.14 OWF48040.1 - 1.1e-59 202.1 2.7 1.6e-59 201.5 2.7 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 OWF48040.1 - 4.2e-20 72.2 0.6 1.2e-19 70.8 0.2 2.1 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 OWF48040.1 - 3.1e-14 53.5 0.4 1.7e-13 51.1 0.1 2.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 OWF48040.1 - 1.2e-13 51.3 0.0 3.9e-09 36.8 0.0 2.9 2 0 0 2 2 2 2 MG2 domain A2M PF00207.22 OWF48040.1 - 3e-11 43.0 0.0 1e-10 41.3 0.0 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG3 PF17791.1 OWF48040.1 - 8.6e-05 22.7 0.0 0.0004 20.6 0.0 2.2 2 0 0 2 2 2 1 Macroglobulin domain MG3 Ldl_recept_a PF00057.18 OWF48040.1 - 0.0012 19.0 11.7 0.0021 18.2 11.7 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A MG4 PF17789.1 OWF48040.1 - 0.022 14.9 0.1 0.28 11.4 0.2 2.8 3 0 0 3 3 3 0 Macroglobulin domain MG4 PrmA PF06325.13 OWF48041.1 - 7.6e-12 45.2 1.0 4.7e-07 29.5 0.0 2.5 3 0 0 3 3 3 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OWF48041.1 - 1.3e-10 41.9 0.0 5.9e-05 23.7 0.1 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OWF48041.1 - 9e-08 32.7 0.0 0.014 16.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Met_10 PF02475.16 OWF48041.1 - 3.6e-06 26.9 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 OWF48041.1 - 1.6e-05 24.5 0.0 0.004 16.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Cons_hypoth95 PF03602.15 OWF48041.1 - 1.8e-05 24.4 0.0 0.096 12.3 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 OWF48041.1 - 0.0013 17.9 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.7 OWF48041.1 - 0.0065 16.4 0.0 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF48041.1 - 0.0082 16.0 0.0 0.037 13.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 OWF48041.1 - 0.019 14.7 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_31 PF13847.6 OWF48041.1 - 0.027 14.3 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 OWF48041.1 - 0.057 12.5 0.0 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 OWF48041.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_2 PF12796.7 OWF48042.1 - 2.2e-32 111.5 5.0 1.2e-13 51.4 0.1 4.2 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48042.1 - 8.8e-31 105.9 9.0 1.1e-08 35.5 0.0 5.4 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF48042.1 - 6.3e-27 93.3 2.0 4.2e-07 30.1 0.1 6.3 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF48042.1 - 4.4e-24 81.9 5.2 0.0022 18.4 0.1 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 OWF48042.1 - 1.1e-20 73.1 5.6 0.00028 21.2 0.2 7.5 7 0 0 7 7 7 4 Ankyrin repeat SOCS_box PF07525.16 OWF48042.1 - 2.7e-08 34.0 5.5 2.7e-08 34.0 5.5 2.4 2 0 0 2 2 2 1 SOCS box Phage_T7_Capsid PF05396.11 OWF48042.1 - 0.0083 16.5 0.3 0.48 10.8 0.3 3.2 4 0 0 4 4 4 1 Phage T7 capsid assembly protein Shigella_OspC PF06128.11 OWF48042.1 - 0.2 11.4 6.8 0.38 10.4 0.0 3.3 2 1 1 3 3 3 0 Shigella flexneri OspC protein tRNA-synt_2 PF00152.20 OWF48043.1 - 1e-77 261.3 0.0 1.6e-77 260.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OWF48043.1 - 9.2e-13 48.0 0.0 2.4e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OWF48043.1 - 1.2e-07 31.5 0.0 0.0071 15.9 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Bul1_C PF04426.12 OWF48043.1 - 0.68 9.3 6.7 1.2 8.5 6.7 1.3 1 0 0 1 1 1 0 Bul1 C terminus EF-hand_1 PF00036.32 OWF48044.1 - 1.4e-34 115.0 13.9 5.7e-07 28.6 0.3 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 OWF48044.1 - 6.5e-31 103.6 17.5 6.4e-06 25.7 0.3 6.9 7 1 0 7 7 6 6 EF-hand domain EF-hand_7 PF13499.6 OWF48044.1 - 2e-29 101.8 17.8 3.9e-11 43.2 0.7 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF48044.1 - 1.6e-23 81.1 18.7 6.8e-05 22.2 0.2 6.5 6 0 0 6 6 6 6 EF hand EF-hand_8 PF13833.6 OWF48044.1 - 3e-11 43.0 13.3 0.011 15.6 0.1 5.5 4 2 2 6 6 6 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF48044.1 - 5.7e-06 26.6 0.0 13 6.2 0.1 5.2 5 1 0 5 5 5 0 EF-hand domain GPHH PF16905.5 OWF48044.1 - 2.1e-05 24.2 0.1 0.045 13.5 0.0 2.6 2 0 0 2 2 2 2 Voltage-dependent L-type calcium channel, IQ-associated DUF1840 PF08895.11 OWF48044.1 - 3.7e-05 24.0 0.1 0.25 11.7 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1840) SPARC_Ca_bdg PF10591.9 OWF48044.1 - 6.9e-05 23.1 15.7 0.045 14.1 6.8 4.9 2 2 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 OWF48044.1 - 0.00013 22.1 0.2 0.037 14.2 0.0 3.1 3 1 0 3 3 3 1 EF hand EF-hand_10 PF14788.6 OWF48044.1 - 0.00018 21.3 6.0 4.9 7.1 0.1 4.9 5 0 0 5 5 5 2 EF hand Dockerin_1 PF00404.18 OWF48044.1 - 0.0018 18.4 0.2 6.8 7.0 0.1 3.9 4 0 0 4 4 4 1 Dockerin type I domain E2F_TDP PF02319.20 OWF48044.1 - 0.065 13.3 0.5 2.6 8.2 0.0 3.4 2 1 1 3 3 3 0 E2F/DP family winged-helix DNA-binding domain WWE PF02825.20 OWF48044.1 - 0.067 13.8 0.4 6 7.5 0.0 2.9 3 0 0 3 3 3 0 WWE domain p25-alpha PF05517.12 OWF48044.1 - 0.13 12.5 3.9 5.2 7.2 0.2 3.3 3 1 1 4 4 4 0 p25-alpha CRR7 PF12095.8 OWF48044.1 - 0.17 12.4 2.7 27 5.3 0.1 3.3 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 EF-hand_4 PF12763.7 OWF48044.1 - 1.6 8.7 13.1 2.2 8.3 0.7 4.8 2 2 2 5 5 5 0 Cytoskeletal-regulatory complex EF hand Transglut_C PF00927.22 OWF48045.1 - 1.5e-21 76.5 0.1 1.9e-10 40.8 0.1 2.2 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Glycos_transf_2 PF00535.26 OWF48046.1 - 1e-31 110.0 0.0 1.4e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OWF48046.1 - 2.7e-09 37.3 0.0 5e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OWF48046.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 OWF48046.1 - 2.6e-05 23.8 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OWF48046.1 - 0.21 12.1 0.0 0.49 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Beach PF02138.18 OWF48047.1 - 2e-110 368.5 0.0 3e-110 367.9 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 OWF48047.1 - 2.8e-16 59.6 17.9 0.04 14.8 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF48047.1 - 5.6e-10 39.4 1.8 0.037 14.3 0.1 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 OWF48047.1 - 1.2e-07 31.6 0.2 6.6e-06 26.0 0.1 2.8 2 0 0 2 2 2 1 GRAM domain PH_BEACH PF14844.6 OWF48047.1 - 1.5e-07 31.5 0.2 9.5e-05 22.4 0.1 3.4 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40_like PF17005.5 OWF48047.1 - 0.00085 18.7 6.4 0.061 12.6 0.3 2.7 3 0 0 3 3 3 2 WD40-like domain Vps36_ESCRT-II PF11605.8 OWF48047.1 - 0.0046 17.1 0.1 4.1 7.7 0.0 2.9 3 0 0 3 3 3 2 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 OWF48047.1 - 0.13 12.7 0.0 34 4.8 0.0 2.7 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain E1_DerP2_DerF2 PF02221.15 OWF48048.1 - 6.7e-07 29.8 0.0 9.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ML domain PAP1 PF08601.10 OWF48048.1 - 0.13 12.0 0.2 0.17 11.6 0.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 adh_short PF00106.25 OWF48049.1 - 4.2e-48 163.4 0.2 8.9e-48 162.3 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF48049.1 - 5.5e-40 137.4 0.1 6.8e-40 137.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF48049.1 - 1.7e-11 44.4 0.1 4.8e-11 42.9 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF48049.1 - 0.00022 20.8 0.0 0.00036 20.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF48049.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OWF48049.1 - 0.0024 16.9 0.7 0.0038 16.3 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PQ-loop PF04193.14 OWF48050.1 - 4.1e-25 87.3 0.5 1.1e-14 53.9 0.0 3.6 4 0 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 OWF48050.1 - 0.0038 18.0 3.6 1.6 9.5 1.9 2.4 2 1 0 2 2 2 2 ER lumen protein retaining receptor DUF2826 PF11442.8 OWF48050.1 - 0.031 14.1 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) DUF3341 PF11821.8 OWF48050.1 - 0.64 9.6 5.5 3.3 7.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) DUF2244 PF10003.9 OWF48050.1 - 0.97 9.1 0.0 0.97 9.1 0.0 2.7 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) DUF4834 PF16118.5 OWF48050.1 - 9.2 7.3 7.5 10 7.2 1.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Ets PF00178.22 OWF48051.1 - 1e-35 122.1 0.2 1.9e-35 121.2 0.2 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 OWF48051.1 - 6.6e-20 70.9 0.1 1.2e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ets PF00178.22 OWF48053.1 - 4.5e-36 123.2 0.5 6.4e-36 122.7 0.5 1.2 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 OWF48053.1 - 0.047 14.3 0.4 0.07 13.7 0.4 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Aminotran_3 PF00202.21 OWF48054.1 - 2.6e-87 293.1 0.0 5.2e-87 292.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Sushi PF00084.20 OWF48055.1 - 4e-13 49.7 2.0 9.9e-10 38.9 0.4 2.5 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) PAN_1 PF00024.26 OWF48055.1 - 1.5e-06 28.0 0.9 3.3e-06 27.0 0.9 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF48055.1 - 0.0098 15.8 0.3 0.033 14.1 0.3 1.9 1 0 0 1 1 1 1 PAN domain HRM PF02793.22 OWF48055.1 - 6.5 7.1 9.7 10 6.5 0.2 3.3 3 1 0 3 3 3 0 Hormone receptor domain Peptidase_S10 PF00450.22 OWF48056.1 - 1.2e-97 327.9 0.8 1.5e-97 327.6 0.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 OWF48056.1 - 0.063 12.7 0.1 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family 7tm_1 PF00001.21 OWF48057.1 - 5.6e-19 68.5 18.7 5.6e-19 68.5 18.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF48057.1 - 3.1e-11 43.1 20.6 1.3e-09 37.8 20.6 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF48057.1 - 2e-08 34.2 16.8 2e-08 34.2 16.8 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cytochrom_B_N_2 PF13631.6 OWF48057.1 - 1.2 9.1 9.8 0.43 10.6 2.6 2.5 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB OB_NTP_bind PF07717.16 OWF48058.1 - 8.1e-22 77.4 0.0 9.6e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DHC_N1 PF08385.12 OWF48059.1 - 1.5e-178 595.0 12.2 1.5e-178 595.0 12.2 3.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OWF48059.1 - 2.6e-144 480.2 0.0 1.1e-142 474.8 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF48059.1 - 3.8e-127 424.7 10.1 3.8e-127 424.7 10.1 4.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF48059.1 - 2e-96 322.9 0.1 8.2e-96 320.8 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF48059.1 - 1.6e-93 312.8 0.0 4.6e-93 311.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF48059.1 - 6.9e-83 277.1 0.6 6.9e-83 277.1 0.6 4.6 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF48059.1 - 1e-69 233.6 1.0 4.4e-63 212.1 0.1 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF48059.1 - 2e-54 183.8 0.1 5.1e-54 182.5 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 OWF48059.1 - 9.7e-50 169.5 13.0 2.5e-49 168.2 13.0 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OWF48059.1 - 1.3e-40 138.2 0.6 1e-39 135.3 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OWF48059.1 - 1.8e-22 79.8 0.0 6.6e-07 29.4 0.0 5.8 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OWF48059.1 - 2.6e-20 72.8 0.6 3.4e-18 66.0 0.5 3.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OWF48059.1 - 1.1e-17 64.1 0.0 5.4e-17 61.8 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OWF48059.1 - 1e-07 32.5 0.5 1.1 9.6 0.0 5.1 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF48059.1 - 9.7e-05 22.8 0.2 2.6 8.4 0.0 5.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 OWF48059.1 - 0.00029 21.1 0.4 38 4.5 0.0 5.1 4 0 0 4 4 4 0 AAA domain HlyE PF06109.13 OWF48059.1 - 0.0068 15.8 1.1 0.031 13.6 1.1 2.2 1 0 0 1 1 1 1 Haemolysin E (HlyE) RNA_helicase PF00910.22 OWF48059.1 - 0.042 14.2 0.8 8 6.9 0.0 4.3 4 0 0 4 4 4 0 RNA helicase Roc PF08477.13 OWF48059.1 - 0.042 14.1 0.0 19 5.5 0.0 3.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 OWF48059.1 - 0.056 13.8 8.9 5.1 7.4 0.0 4.6 4 0 0 4 4 4 0 AAA domain DUF4041 PF13250.6 OWF48059.1 - 0.091 12.7 0.8 2.3 8.1 0.0 4.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4041) FtsK_SpoIIIE PF01580.18 OWF48059.1 - 0.32 10.3 2.3 8.4 5.7 0.0 3.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family ORC6 PF05460.13 OWF48060.1 - 5.2e-07 29.3 4.5 0.00046 19.6 4.5 2.4 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) TFIIB PF00382.19 OWF48060.1 - 0.0015 18.5 1.5 0.025 14.6 0.1 2.9 3 0 0 3 3 3 1 Transcription factor TFIIB repeat DUF2852 PF11014.8 OWF48060.1 - 0.043 14.0 0.7 0.098 12.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SYS1 PF09801.9 OWF48061.1 - 3.2e-47 160.3 8.1 3.7e-47 160.1 8.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CCSMST1 PF15013.6 OWF48061.1 - 0.17 12.0 1.0 6.3 7.0 0.1 2.4 2 0 0 2 2 2 0 CCSMST1 family COX4 PF02936.14 OWF48062.1 - 3e-25 88.8 0.0 4.5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4618 PF15397.6 OWF48063.1 - 5.3e-68 229.2 24.1 6.8e-68 228.9 24.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Syntaxin-6_N PF09177.11 OWF48063.1 - 0.027 15.0 0.6 0.027 15.0 0.6 3.7 1 1 1 4 4 4 0 Syntaxin 6, N-terminal PSD4 PF07631.11 OWF48063.1 - 0.087 13.4 0.3 0.087 13.4 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) SLATT_5 PF18160.1 OWF48063.1 - 0.14 11.4 8.3 0.64 9.3 0.5 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4407 PF14362.6 OWF48063.1 - 0.43 9.9 11.1 1.4 8.2 9.7 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 OWF48063.1 - 8.8 6.9 22.3 0.074 13.5 1.2 4.2 4 1 1 5 5 5 0 Spectrin repeat Cu-oxidase_3 PF07732.15 OWF48064.1 - 1.1e-36 125.4 0.1 1.1e-36 125.4 0.1 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF48064.1 - 1.9e-34 118.3 0.4 1.9e-34 118.3 0.4 4.3 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 OWF48064.1 - 5.3e-30 104.6 0.2 5.4e-24 85.1 0.0 3.4 3 0 0 3 3 3 3 Multicopper oxidase G-alpha PF00503.20 OWF48065.1 - 1.8e-85 287.2 3.7 2.2e-85 286.9 3.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OWF48065.1 - 5.9e-15 55.1 0.7 1.9e-11 43.7 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF48065.1 - 8.5e-05 22.0 2.2 0.0032 16.8 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OWF48065.1 - 0.0021 18.3 0.3 2.2 8.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OWF48065.1 - 0.014 14.8 0.3 0.075 12.4 0.3 1.9 2 0 0 2 2 2 0 Bacterial TniB protein GTP_EFTU PF00009.27 OWF48065.1 - 0.024 14.2 0.0 0.66 9.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 OWF48065.1 - 0.065 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain 7tm_1 PF00001.21 OWF48066.1 - 4.9e-24 85.1 7.7 5.6e-24 84.9 7.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srh PF10318.9 OWF48066.1 - 0.011 14.8 7.4 0.013 14.5 7.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh US10 PF17617.2 OWF48066.1 - 0.03 14.4 1.0 0.04 14.0 1.0 1.3 1 0 0 1 1 1 0 Viral unique short region 10 7TM_GPCR_Srd PF10317.9 OWF48066.1 - 3.8 6.6 14.5 1.1e+02 1.8 14.4 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd COX7a PF02238.15 OWF48066.1 - 7.3 7.1 6.7 40 4.7 3.3 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Cuticle_3 PF11018.8 OWF48069.1 - 2.2e-06 28.0 0.2 0.65 10.2 0.1 4.2 1 1 3 4 4 4 2 Pupal cuticle protein C1 HTH_10 PF04967.12 OWF48069.1 - 0.00043 20.0 9.0 19 5.1 0.0 7.2 6 2 2 8 8 8 1 HTH DNA binding domain SFTA2 PF15210.6 OWF48069.1 - 0.0069 16.3 2.2 1.6e+02 2.3 0.0 6.2 4 3 4 8 8 8 0 Surfactant-associated protein 2 Glyoxalase_4 PF13669.6 OWF48069.1 - 0.0073 16.6 0.0 46 4.3 0.0 4.7 1 1 2 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pim PF16765.5 OWF48069.1 - 3.4 7.9 13.0 14 5.9 0.6 4.4 1 1 4 6 6 6 0 Pesticin immunity protein PPL4 PF18188.1 OWF48070.1 - 0.4 10.6 9.7 0.31 11.0 0.9 2.2 1 1 1 2 2 2 0 Prim-pol 4 FKBP_N_2 PF18023.1 OWF48071.1 - 0.019 15.0 0.5 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 BDBT FKBP like N-terminal Cytidylate_kin2 PF13189.6 OWF48071.1 - 0.092 12.9 0.1 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family Glyco_hydro_10 PF00331.20 OWF48072.1 - 2.9e-46 158.1 4.4 5.2e-46 157.2 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 OWF48072.1 - 1.6e-13 51.1 2.8 1.6e-13 51.1 2.8 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain Phage_P2_GpE PF06528.12 OWF48072.1 - 0.028 14.0 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Phage P2 GpE DUF4132 PF13569.6 OWF48072.1 - 0.077 12.8 0.9 0.24 11.2 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4132) DUF4923 PF16270.5 OWF48072.1 - 0.084 12.7 1.6 0.43 10.4 0.0 2.5 3 0 0 3 3 3 0 Lipocalin-like domain (DUF4923) Glyco_hydro_10 PF00331.20 OWF48073.1 - 3.8e-40 138.0 2.9 3.8e-40 138.0 2.9 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 OWF48073.1 - 2.3e-11 44.1 0.4 1.2e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain Glyco_hydro_cc PF11790.8 OWF48073.1 - 0.0013 18.4 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF3859 PF12975.7 OWF48073.1 - 0.059 13.3 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Big_9 PF17963.1 OWF48074.1 - 1.8e-07 31.8 0.0 1.8e-07 31.8 0.0 5.2 5 0 0 5 5 5 1 Bacterial Ig domain Cadherin_4 PF17803.1 OWF48074.1 - 3.7e-06 27.5 4.7 0.00016 22.2 0.0 4.3 3 0 0 3 3 3 1 Bacterial cadherin-like domain Cadherin_5 PF17892.1 OWF48074.1 - 0.00029 20.8 1.4 0.0016 18.4 0.0 2.9 3 0 0 3 3 3 1 Cadherin-like domain PAN_1 PF00024.26 OWF48075.1 - 1.5e-05 24.9 0.2 1.5e-05 24.9 0.2 2.3 3 0 0 3 3 3 1 PAN domain ANF_receptor PF01094.28 OWF48076.1 - 1.7e-72 244.5 2.0 6.4e-30 104.5 0.2 3.1 3 0 0 3 3 3 3 Receptor family ligand binding region 7tm_3 PF00003.22 OWF48076.1 - 7.8e-08 32.3 27.4 1.6e-07 31.3 27.2 1.6 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 OWF48076.1 - 0.00096 18.9 0.0 0.048 13.3 0.0 3.1 3 1 1 4 4 4 1 Periplasmic binding protein PAPS_reduct PF01507.19 OWF48076.1 - 0.55 10.2 2.3 4 7.4 0.5 2.3 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Galactosyl_T PF01762.21 OWF48077.1 - 4.9e-49 166.8 1.3 6.8e-49 166.3 1.3 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF48077.1 - 0.00039 19.9 0.2 0.00058 19.4 0.2 1.2 1 0 0 1 1 1 1 Fringe-like Rhomboid_N PF12122.8 OWF48077.1 - 0.021 15.0 0.0 0.76 10.0 0.0 2.7 3 0 0 3 3 3 0 Cytoplasmic N-terminal domain of rhomboid serine protease Gal-3-0_sulfotr PF06990.11 OWF48079.1 - 5.2e-38 131.0 1.7 8.9e-38 130.2 1.7 1.3 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF48079.1 - 0.00013 22.0 1.1 0.00037 20.5 0.1 2.2 2 1 0 2 2 2 1 Sulfotransferase family Lipocalin PF00061.23 OWF48080.1 - 1.7e-08 34.8 0.4 2.1e-08 34.5 0.4 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Baseplate_J PF04865.14 OWF48080.1 - 0.035 13.3 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Baseplate J-like protein DS PF01916.17 OWF48081.1 - 9.1e-128 425.5 0.0 1.1e-127 425.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase VWD PF00094.25 OWF48082.1 - 5.4e-43 147.0 12.8 1.5e-25 90.3 6.8 2.4 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 OWF48082.1 - 2.4e-12 47.1 7.5 6.7e-07 29.6 0.2 5.8 5 0 0 5 5 5 2 C8 domain TIL PF01826.17 OWF48082.1 - 1.2e-11 44.7 31.0 1.8e-07 31.3 9.7 8.9 9 1 0 9 9 9 2 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 OWF48082.1 - 2.6e-10 40.3 70.4 5.8e-06 26.4 8.0 8.2 7 0 0 7 7 7 4 EGF domain EGF_CA PF07645.15 OWF48082.1 - 0.00055 20.1 3.3 0.00055 20.1 3.3 8.8 8 0 0 8 8 8 3 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 OWF48082.1 - 0.0034 17.4 5.3 0.0034 17.4 5.3 8.3 8 1 0 8 8 8 3 MSP1 EGF domain 1 G8 PF10162.9 OWF48083.1 - 1.1e-26 93.3 0.0 4.5e-26 91.3 0.0 2.1 2 0 0 2 2 2 1 G8 domain TMEM154 PF15102.6 OWF48083.1 - 0.00052 19.9 7.0 0.0014 18.6 7.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 OWF48083.1 - 0.015 15.6 2.8 0.034 14.4 2.8 1.6 1 0 0 1 1 1 0 Glycophorin A RIFIN PF02009.16 OWF48083.1 - 0.035 14.0 1.1 0.061 13.2 1.1 1.3 1 0 0 1 1 1 0 Rifin Shisa PF13908.6 OWF48083.1 - 0.68 10.2 7.6 0.69 10.1 5.6 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator AJAP1_PANP_C PF15298.6 OWF48083.1 - 2 8.6 12.0 5.6 7.1 12.0 1.7 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TIG PF01833.24 OWF48084.1 - 5.4e-109 356.5 108.6 6.4e-13 48.6 4.1 13.9 13 0 0 13 13 13 11 IPT/TIG domain G8 PF10162.9 OWF48084.1 - 7.1e-37 126.2 2.2 2.3e-36 124.6 0.5 2.9 2 0 0 2 2 2 1 G8 domain Qn_am_d_aIII PF09099.10 OWF48084.1 - 0.0036 17.7 8.3 1.2 9.6 0.0 5.8 6 0 0 6 6 6 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III G6PD_bact PF10786.9 OWF48084.1 - 1.1 8.8 2.6 2 7.9 2.6 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Beta_helix PF13229.6 OWF48084.1 - 3.8 7.3 40.4 0.057 13.3 15.3 6.2 3 1 0 3 3 3 0 Right handed beta helix region TIG PF01833.24 OWF48085.1 - 3.5e-16 59.1 7.6 2.1e-10 40.5 1.7 2.3 2 1 0 2 2 2 2 IPT/TIG domain Methyltransf_22 PF13383.6 OWF48086.1 - 2.3e-24 86.4 3.8 2.3e-23 83.0 0.6 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 OWF48086.1 - 1.6e-08 34.8 0.0 0.0054 16.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase FkbM domain Ank_2 PF12796.7 OWF48087.1 - 9.8e-94 308.1 10.6 2.9e-11 43.8 0.5 11.9 1 1 11 12 12 12 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF48087.1 - 4.3e-83 272.3 11.4 2.2e-06 27.8 0.0 18.8 10 8 10 20 20 20 14 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF48087.1 - 1.1e-55 185.2 15.1 2.4e-07 31.2 0.1 13.1 8 2 6 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF48087.1 - 3.9e-51 165.0 18.9 0.00037 20.7 0.0 18.5 21 1 0 21 21 21 10 Ankyrin repeat Ank PF00023.30 OWF48087.1 - 3.1e-44 147.5 17.6 0.00068 20.0 0.1 18.4 20 0 0 20 20 20 9 Ankyrin repeat AnkUBD PF18418.1 OWF48087.1 - 1e-06 28.8 0.1 9.8 6.4 0.0 7.1 7 0 0 7 7 7 1 Ankyrin ubiquitin-binding domain Regnase_1_C PF18561.1 OWF48087.1 - 0.022 14.5 0.0 22 4.9 0.0 5.3 8 0 0 8 8 8 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain DUF1013 PF06242.11 OWF48087.1 - 0.05 13.7 0.1 12 6.0 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1013) DUF3849 PF12960.7 OWF48087.1 - 0.37 10.8 2.8 12 5.9 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3849) FDX-ACB PF03147.14 OWF48088.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain ABC_membrane PF00664.23 OWF48089.1 - 5.4e-57 193.5 3.3 5.4e-57 193.5 3.3 2.4 3 0 0 3 3 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 OWF48089.1 - 3.1e-33 115.2 0.0 5.9e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF48089.1 - 8.2e-07 28.7 3.1 1.6e-06 27.7 0.9 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OWF48089.1 - 0.00051 20.0 0.0 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 OWF48089.1 - 0.00064 19.1 0.2 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 OWF48089.1 - 0.001 19.5 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MENTAL PF10457.9 OWF48089.1 - 0.0021 17.9 2.3 0.0021 17.9 2.3 1.9 2 0 0 2 2 2 1 Cholesterol-capturing domain AAA_22 PF13401.6 OWF48089.1 - 0.023 15.0 0.1 0.23 11.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OWF48089.1 - 0.046 13.5 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 OWF48089.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OWF48089.1 - 0.079 12.7 0.2 0.37 10.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 OWF48089.1 - 0.13 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain ANF_receptor PF01094.28 OWF48090.1 - 3.1e-182 605.4 20.0 2.3e-45 155.3 0.9 5.4 5 0 0 5 5 5 5 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF48090.1 - 1.7e-40 139.8 14.6 4.5e-12 46.3 0.1 5.5 5 0 0 5 5 5 5 Periplasmic binding protein 7tm_3 PF00003.22 OWF48090.1 - 1.3e-28 100.4 18.8 2.3e-28 99.6 18.8 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_1 PF00001.21 OWF48091.1 - 5.2e-44 150.5 15.9 7.2e-44 150.1 15.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF48091.1 - 2.3e-09 37.0 13.5 3.3e-09 36.5 13.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF48091.1 - 2e-07 30.9 15.5 3.2e-07 30.2 15.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF48091.1 - 0.00017 21.4 2.3 0.00017 21.4 2.3 2.1 2 1 0 2 2 2 1 Olfactory receptor GAS2 PF02187.17 OWF48092.1 - 1.1e-31 108.7 0.1 2.4e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 OWF48092.1 - 8.7e-14 51.6 0.1 2e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Phospholip_A2_2 PF05826.12 OWF48093.1 - 1.6e-35 121.2 3.6 2.7e-35 120.5 3.6 1.4 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 OWF48093.1 - 0.2 12.1 9.4 7.3 7.1 9.4 2.5 1 1 0 1 1 1 0 Phospholipase A2 PTR2 PF00854.21 OWF48094.1 - 7.7e-81 271.9 3.2 4.2e-47 160.8 0.2 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.16 OWF48094.1 - 4.1e-08 32.5 19.9 0.00054 19.0 0.7 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF48094.1 - 0.00044 19.2 7.9 0.012 14.5 2.1 2.9 3 0 0 3 3 3 2 MFS_1 like family Y_phosphatase3 PF13350.6 OWF48095.1 - 5.2e-40 137.9 0.0 1.3e-30 107.1 0.0 2.0 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OWF48095.1 - 3.1e-05 23.6 0.0 6.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Kp4 PF09044.10 OWF48095.1 - 0.0027 17.8 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 Kp4 PTPlike_phytase PF14566.6 OWF48095.1 - 0.0086 16.2 0.4 2.9 8.0 0.1 2.2 2 0 0 2 2 2 2 Inositol hexakisphosphate BTB_2 PF02214.22 OWF48096.1 - 7.4e-16 58.3 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OWF48096.1 - 2.9e-05 24.1 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sulfotransfer_1 PF00685.27 OWF48097.1 - 6.4e-44 150.4 0.1 1e-42 146.4 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF48097.1 - 0.0066 16.9 0.0 0.017 15.5 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Spermine_synth PF01564.17 OWF48098.1 - 6.9e-61 204.9 0.0 1.1e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OWF48098.1 - 1.7e-22 79.1 0.2 2.9e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OWF48098.1 - 0.00015 22.4 0.1 0.00041 21.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 OWF48098.1 - 0.0035 16.6 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain RrnaAD PF00398.20 OWF48098.1 - 0.0064 15.6 0.0 0.0099 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 OWF48098.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_PK PF05891.12 OWF48098.1 - 0.044 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_12 PF08242.12 OWF48098.1 - 0.061 14.1 0.0 0.17 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GSHPx PF00255.19 OWF48099.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase GSHPx PF00255.19 OWF48100.1 - 0.00011 21.7 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 OWF48101.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase GSHPx PF00255.19 OWF48102.1 - 5.5e-19 67.7 0.0 8.1e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Death PF00531.22 OWF48103.1 - 1.8e-12 47.3 0.0 5.5e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Death domain TIR PF01582.20 OWF48103.1 - 2.4e-06 27.5 0.2 9.7e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 TIR domain TIR_2 PF13676.6 OWF48103.1 - 7e-06 26.6 0.0 1.4e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain Death PF00531.22 OWF48104.1 - 2.7e-07 30.7 0.0 5.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Death domain TIR_2 PF13676.6 OWF48104.1 - 4.4e-07 30.5 0.0 9.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF48104.1 - 1.2e-05 25.2 0.0 0.00022 21.1 0.0 2.3 2 0 0 2 2 2 1 TIR domain GKAP PF03359.13 OWF48105.1 - 8.9e-38 130.7 0.2 8.9e-38 130.7 0.2 4.2 3 2 2 5 5 5 1 Guanylate-kinase-associated protein (GKAP) protein Adhesin_P1_N PF18652.1 OWF48105.1 - 8.6 6.5 8.9 0.17 11.9 1.6 1.9 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain SLATT_5 PF18160.1 OWF48106.1 - 0.002 17.5 0.1 0.0023 17.3 0.1 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 LRRNT PF01462.18 OWF48106.1 - 0.0072 16.0 0.9 0.012 15.2 0.9 1.4 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF5058 PF16481.5 OWF48106.1 - 0.018 14.8 1.3 0.022 14.5 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5058) DUF3611 PF12263.8 OWF48106.1 - 0.022 14.6 0.6 0.028 14.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) SfLAP PF11139.8 OWF48106.1 - 0.046 13.2 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein zf-RING_2 PF13639.6 OWF48107.1 - 6.7e-09 35.9 6.1 6.7e-09 35.9 6.1 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF48107.1 - 1e-06 28.4 5.0 1.6e-06 27.7 3.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OWF48107.1 - 1.1e-06 28.4 8.4 4e-06 26.6 8.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF48107.1 - 1.7e-06 27.7 6.4 4.8e-06 26.3 6.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OWF48107.1 - 1.6e-05 24.6 4.1 3.9e-05 23.4 4.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OWF48107.1 - 2.9e-05 24.0 5.1 8.8e-05 22.5 5.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OWF48107.1 - 0.00077 19.7 11.3 0.00077 19.7 11.3 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF48107.1 - 0.0012 18.8 9.9 0.0012 18.7 7.6 2.3 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OWF48107.1 - 0.0015 18.1 4.7 0.0015 18.1 4.7 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OWF48107.1 - 0.028 14.6 6.7 0.028 14.6 6.7 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OWF48107.1 - 0.039 14.0 7.9 0.09 12.8 7.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 OWF48107.1 - 0.98 9.5 8.1 3.9 7.6 8.1 2.1 1 1 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 OWF48107.1 - 5.8 6.8 12.2 0.17 11.7 4.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OWF48108.1 - 5.4e-07 29.8 9.5 5.4e-07 29.8 9.5 2.1 2 1 1 3 3 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF48108.1 - 1.5e-06 27.9 4.1 5.1e-06 26.1 4.1 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF48108.1 - 3.8e-06 26.6 11.2 8.3e-06 25.5 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF48108.1 - 8.4e-06 26.0 6.7 8.4e-06 26.0 6.7 2.4 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF48108.1 - 2.3e-05 24.2 12.9 2.3e-05 24.2 12.9 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF48108.1 - 4.6e-05 23.3 5.3 0.00012 22.1 5.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF48108.1 - 0.00011 22.1 10.0 0.00011 22.1 10.0 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-Nse PF11789.8 OWF48108.1 - 0.00013 21.7 6.4 0.00025 20.8 6.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HisKA_7TM PF16927.5 OWF48108.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase CD34_antigen PF06365.12 OWF48108.1 - 0.028 14.0 1.2 0.031 13.9 0.1 1.8 2 0 0 2 2 2 0 CD34/Podocalyxin family EphA2_TM PF14575.6 OWF48108.1 - 0.036 15.0 5.5 0.68 10.8 3.8 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 7TM_GPCR_Str PF10326.9 OWF48108.1 - 0.072 12.4 0.5 0.096 12.0 0.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF2207 PF09972.9 OWF48108.1 - 0.078 11.7 0.3 0.098 11.4 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 OWF48108.1 - 0.097 13.0 3.6 0.2 12.0 0.0 2.2 1 1 1 2 2 2 0 Orf78 (ac78) Saf_2TM PF18303.1 OWF48108.1 - 0.15 11.7 0.9 0.89 9.1 0.0 2.2 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain zf-ANAPC11 PF12861.7 OWF48108.1 - 0.27 11.3 10.9 0.23 11.6 8.9 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Protocadherin PF08374.11 OWF48108.1 - 0.53 10.2 2.9 0.48 10.4 0.1 2.1 2 0 0 2 2 2 0 Protocadherin RCR PF12273.8 OWF48108.1 - 0.9 10.2 4.6 1.9 9.2 1.0 2.8 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red zf-C3H2C3 PF17122.5 OWF48108.1 - 1.8 8.7 9.6 6.6 6.9 9.6 2.0 1 1 0 1 1 1 0 Zinc-finger TIMELESS PF04821.14 OWF48109.1 - 1.9e-75 253.7 5.0 1.9e-75 253.7 5.0 3.5 4 0 0 4 4 4 1 Timeless protein TIMELESS_C PF05029.13 OWF48109.1 - 5.4e-57 194.2 1.0 5.4e-57 194.2 1.0 3.7 2 1 1 3 3 3 2 Timeless protein C terminal region HflK_N PF12221.8 OWF48109.1 - 0.14 12.2 0.9 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial membrane protein N terminal PX PF00787.24 OWF48110.1 - 3.1e-22 78.7 1.0 9.7e-22 77.1 0.0 2.3 3 0 0 3 3 3 1 PX domain Vps5 PF09325.10 OWF48110.1 - 2.4e-08 33.8 17.7 3.5e-05 23.5 8.7 2.2 1 1 1 2 2 2 2 Vps5 C terminal like FAM92 PF06730.11 OWF48110.1 - 1.4e-05 24.6 6.1 3.9e-05 23.2 6.1 1.7 1 1 0 1 1 1 1 FAM92 protein GAS PF13851.6 OWF48110.1 - 0.0078 15.6 1.0 0.0078 15.6 1.0 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 OWF48110.1 - 0.074 11.0 9.1 0.0064 14.5 2.9 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 OWF48110.1 - 0.26 11.7 4.4 0.32 11.4 1.1 2.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF745 PF05335.13 OWF48110.1 - 0.36 10.5 4.9 0.7 9.6 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Bacillus_HBL PF05791.11 OWF48110.1 - 0.4 10.5 7.1 0.58 10.0 3.7 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.11 OWF48110.1 - 0.57 10.6 3.4 15 6.1 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Sugarporin_N PF11471.8 OWF48110.1 - 0.92 9.5 6.9 2 8.4 6.9 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Csm1_N PF18504.1 OWF48110.1 - 1.9 8.9 13.4 0.17 12.2 6.7 2.7 3 0 0 3 3 2 0 Csm1 N-terminal domain P4Ha_N PF08336.11 OWF48110.1 - 2.1 8.4 7.1 6.3 6.8 1.2 3.2 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HlyD_2 PF12700.7 OWF48110.1 - 2.6 6.7 12.2 0.21 10.3 6.7 1.8 2 0 0 2 2 2 0 HlyD family secretion protein FlxA PF14282.6 OWF48110.1 - 3.4 7.7 15.5 0.15 12.1 7.6 2.6 3 0 0 3 3 3 0 FlxA-like protein Tropomyosin_1 PF12718.7 OWF48110.1 - 3.5 7.8 16.7 3.4 7.8 11.8 2.7 2 1 0 2 2 2 0 Tropomyosin like XhlA PF10779.9 OWF48110.1 - 4.7 7.5 6.4 33 4.8 0.3 2.7 2 0 0 2 2 2 0 Haemolysin XhlA GrpE PF01025.19 OWF48110.1 - 5.7 6.6 14.3 0.069 12.8 3.8 2.6 3 0 0 3 3 3 0 GrpE Guanylate_cyc PF00211.20 OWF48111.1 - 2.6e-56 190.2 0.0 4.4e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 OWF48111.1 - 2.9e-22 80.3 0.0 5.1e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 OWF48111.1 - 2.7e-06 27.0 0.1 4.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Heme NO binding associated YopD PF05844.12 OWF48111.1 - 0.057 12.4 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 YopD protein DUF3479 PF11965.8 OWF48111.1 - 0.11 12.6 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) STAT_bind PF02864.15 OWF48112.1 - 1.4e-31 109.8 2.4 1.4e-31 109.8 2.4 2.7 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 OWF48112.1 - 3.4e-22 79.2 21.3 1.2e-21 77.4 19.0 2.9 2 1 0 2 2 2 1 STAT protein, all-alpha domain STAT_int PF02865.17 OWF48112.1 - 4.7e-21 75.5 1.4 4.7e-21 75.5 1.4 3.8 4 1 0 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.24 OWF48112.1 - 6.8e-10 38.9 0.0 3.2e-09 36.7 0.0 2.2 1 0 0 1 1 1 1 SH2 domain SH3BP5 PF05276.14 OWF48113.1 - 4.1e-59 200.2 25.8 7.4e-59 199.3 25.8 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) TMPIT PF07851.13 OWF48113.1 - 0.0023 17.3 1.1 0.0023 17.3 1.1 2.4 2 0 0 2 2 2 1 TMPIT-like protein 7tm_1 PF00001.21 OWF48115.1 - 2.5e-11 43.4 5.7 3.1e-11 43.1 5.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF48115.1 - 3.2e-05 23.4 7.9 4.5e-05 23.0 7.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF48115.1 - 6.4e-05 22.7 13.1 8.1e-05 22.4 13.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF48115.1 - 0.00043 20.1 4.6 0.00057 19.7 4.6 1.1 1 0 0 1 1 1 1 Olfactory receptor RNase_T PF00929.24 OWF48116.1 - 9.1e-12 45.8 0.0 7.5e-11 42.8 0.0 2.4 2 1 0 2 2 2 1 Exonuclease DUF5051 PF16473.5 OWF48116.1 - 0.0075 16.3 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like SAM_Exu PF18609.1 OWF48116.1 - 0.021 14.9 0.1 0.056 13.5 0.1 1.7 1 0 0 1 1 1 0 Exuperantia SAM-like domain RNase_H_2 PF13482.6 OWF48116.1 - 0.035 14.1 0.1 14 5.6 0.0 3.1 2 1 1 3 3 3 0 RNase_H superfamily Prominin PF05478.11 OWF48117.1 - 2.1e-06 26.1 1.8 2.8e-06 25.6 1.8 1.1 1 0 0 1 1 1 1 Prominin HTH_WhiA PF02650.14 OWF48117.1 - 0.0028 18.0 0.2 0.011 16.0 0.2 2.0 1 0 0 1 1 1 1 WhiA C-terminal HTH domain DUF4795 PF16043.5 OWF48117.1 - 0.0033 17.1 0.9 0.0033 17.1 0.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) RPAP3_C PF13877.6 OWF48117.1 - 0.0046 17.5 0.4 2.4 8.8 0.0 2.6 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 BLOC1_2 PF10046.9 OWF48117.1 - 0.01 16.1 2.8 0.28 11.5 0.4 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCC-bdg_PDZ PF10506.9 OWF48117.1 - 0.011 15.7 0.3 0.011 15.7 0.3 2.2 3 0 0 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2959 PF11172.8 OWF48117.1 - 0.011 15.8 0.5 0.011 15.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DUF1664 PF07889.12 OWF48117.1 - 0.013 15.6 4.4 0.026 14.6 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 OWF48117.1 - 0.016 15.6 1.9 0.016 15.6 1.9 3.2 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1825 PF08855.10 OWF48117.1 - 0.03 14.3 0.6 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Lipoprotein_6 PF01441.19 OWF48117.1 - 0.03 14.3 3.4 0.073 13.1 3.4 1.6 1 0 0 1 1 1 0 Lipoprotein Herpes_UL6 PF01763.16 OWF48117.1 - 0.034 12.7 3.1 0.049 12.2 3.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Fib_alpha PF08702.10 OWF48117.1 - 0.038 14.2 3.3 0.085 13.0 3.3 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.6 OWF48117.1 - 0.039 13.5 5.5 0.065 12.8 5.5 1.3 1 0 0 1 1 1 0 TMCO5 family DUF4988 PF16378.5 OWF48117.1 - 0.04 13.6 0.3 0.11 12.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function MctB PF11382.8 OWF48117.1 - 0.043 13.5 0.2 0.074 12.7 0.2 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Wtap PF17098.5 OWF48117.1 - 0.044 13.7 4.6 0.063 13.2 2.0 1.9 1 1 1 2 2 2 0 WTAP/Mum2p family Spore_GerAC PF05504.11 OWF48117.1 - 0.059 13.6 0.8 0.059 13.6 0.8 2.5 1 1 1 3 3 3 0 Spore germination B3/ GerAC like, C-terminal Spc7 PF08317.11 OWF48117.1 - 0.091 11.6 4.7 0.16 10.8 4.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Transposase_22 PF02994.14 OWF48117.1 - 0.17 12.1 2.6 0.31 11.3 0.3 2.4 2 1 0 2 2 2 0 L1 transposable element RBD-like domain DUF4140 PF13600.6 OWF48117.1 - 0.18 12.3 2.7 9.3 6.8 1.2 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 OWF48117.1 - 0.27 11.3 6.4 0.63 10.1 6.4 1.6 1 1 0 1 1 1 0 Laminin Domain II Sec20 PF03908.13 OWF48117.1 - 0.27 11.2 5.2 5 7.1 0.1 2.9 2 1 1 3 3 3 0 Sec20 APG6_N PF17675.1 OWF48117.1 - 0.46 11.0 8.0 0.14 12.6 5.0 1.7 2 0 0 2 2 1 0 Apg6 coiled-coil region Cnn_1N PF07989.11 OWF48117.1 - 0.5 10.6 6.8 0.26 11.5 1.9 2.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 OWF48117.1 - 0.55 10.1 4.1 0.31 10.9 0.7 2.5 2 1 0 2 2 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 OWF48117.1 - 0.64 10.1 5.1 0.27 11.4 0.7 2.7 2 1 1 3 3 2 0 Basic region leucine zipper Troponin PF00992.20 OWF48117.1 - 0.7 10.2 8.0 0.45 10.8 3.1 2.7 2 1 1 3 3 3 0 Troponin Tropomyosin_1 PF12718.7 OWF48117.1 - 1.1 9.5 9.6 1.6 8.9 6.6 2.4 1 1 1 2 2 2 0 Tropomyosin like Fzo_mitofusin PF04799.13 OWF48117.1 - 1.4 8.5 5.5 0.65 9.5 2.5 2.0 2 0 0 2 2 2 0 fzo-like conserved region ZapB PF06005.12 OWF48117.1 - 1.4 9.4 11.1 0.2 12.1 3.0 2.8 2 1 1 3 3 2 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 OWF48117.1 - 1.7 9.3 5.9 13 6.5 5.9 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ADIP PF11559.8 OWF48117.1 - 1.9 8.6 11.8 0.06 13.4 3.8 2.3 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding EGF PF00008.27 OWF48118.1 - 1.6e-51 172.2 249.8 6.4e-07 29.6 6.5 19.8 20 0 0 20 20 20 14 EGF-like domain EGF_CA PF07645.15 OWF48118.1 - 6.9e-32 109.4 288.2 2e-08 34.3 7.2 19.6 14 4 7 21 21 21 9 Calcium-binding EGF domain hEGF PF12661.7 OWF48118.1 - 1.8e-20 72.7 235.7 0.0003 21.3 4.8 21.1 20 1 0 20 20 20 12 Human growth factor-like EGF EGF_2 PF07974.13 OWF48118.1 - 2.2e-15 56.7 279.8 0.00091 19.6 8.9 19.6 16 3 2 18 18 18 12 EGF-like domain EGF_3 PF12947.7 OWF48118.1 - 0.0002 21.5 19.0 0.00029 21.0 4.6 18.4 14 3 3 17 17 17 8 EGF domain DSL PF01414.19 OWF48118.1 - 0.00021 21.5 7.3 0.00021 21.5 7.3 14.0 8 4 6 14 14 14 1 Delta serrate ligand cEGF PF12662.7 OWF48118.1 - 0.055 13.4 0.5 0.055 13.4 0.5 15.7 15 1 0 15 15 15 0 Complement Clr-like EGF-like DSL PF01414.19 OWF48119.1 - 1.8e-73 242.7 326.4 4.1e-05 23.8 9.0 29.5 1 1 30 31 31 31 31 Delta serrate ligand EGF_2 PF07974.13 OWF48119.1 - 3.1e-28 97.8 274.8 0.15 12.5 1.2 31.8 31 0 0 31 31 31 26 EGF-like domain DUF4224 PF13986.6 OWF48120.1 - 0.033 14.1 3.2 24 4.9 0.0 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4224) IL2RB_N1 PF18707.1 OWF48120.1 - 0.19 12.3 4.7 37 4.9 0.3 3.2 1 1 2 3 3 3 0 Interleukin-2 receptor subunit beta N-terminal domain 1 NTP_transf_7 PF07984.12 OWF48121.1 - 2e-161 536.6 2.0 2.5e-161 536.3 2.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase VWA PF00092.28 OWF48122.1 - 3.5e-11 43.7 0.1 5.4e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48122.1 - 1.2e-06 29.1 0.0 3.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF48123.1 - 3.6e-13 50.1 0.0 8.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48123.1 - 7.6e-10 39.4 0.0 4.5e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF48123.1 - 1.4e-07 31.5 27.5 1.3e-05 25.3 1.0 3.9 4 0 0 4 4 4 2 Chitin binding Peritrophin-A domain ApoO PF09769.9 OWF48124.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein O Phage_holin_Dp1 PF16938.5 OWF48125.1 - 0.0033 17.6 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative phage holin Dp-1 TILa PF12714.7 OWF48126.1 - 5.7e-05 23.0 0.8 5.7e-05 23.0 0.8 2.4 2 1 0 2 2 2 1 TILa domain TILa PF12714.7 OWF48127.1 - 0.0099 15.8 1.0 0.0099 15.8 1.0 2.2 2 0 0 2 2 2 1 TILa domain Fibrinogen_C PF00147.18 OWF48129.1 - 2e-30 106.2 3.6 2.7e-30 105.8 3.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF48130.1 - 8.9e-46 156.4 0.6 1.1e-45 156.1 0.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HCO3_cotransp PF00955.21 OWF48131.1 - 2.7e-222 739.1 7.2 3.7e-222 738.7 7.2 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 OWF48131.1 - 1.2e-79 267.9 0.3 2.4e-79 266.9 0.0 1.7 2 0 0 2 2 2 1 Band 3 cytoplasmic domain DUF4732 PF15876.5 OWF48131.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) Ferlin_C PF16165.5 OWF48131.1 - 5.5 6.9 0.0 5.5 6.9 0.0 3.0 2 1 1 3 3 3 0 Ferlin C-terminus HCO3_cotransp PF00955.21 OWF48132.1 - 2.2e-215 716.3 9.5 3.3e-215 715.7 9.5 1.3 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 OWF48132.1 - 1.1e-60 205.8 0.2 1.8e-60 205.1 0.2 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DBR1 PF05011.13 OWF48133.1 - 2.7e-34 118.6 0.4 6.2e-34 117.4 0.0 1.8 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OWF48133.1 - 9e-11 42.6 0.1 1.6e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF48133.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_transf_11 PF01531.16 OWF48134.1 - 9.3e-37 126.8 1.9 1.3e-36 126.4 1.9 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 NodZ PF05830.11 OWF48134.1 - 0.012 14.5 0.0 2.9 6.6 0.0 2.6 2 1 0 3 3 3 0 Nodulation protein Z (NodZ) DUF1033 PF06279.11 OWF48135.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Glyco_transf_11 PF01531.16 OWF48136.1 - 6.1e-37 127.4 1.8 1.1e-36 126.6 1.8 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 11 USP8_dimer PF08969.11 OWF48136.1 - 0.032 14.4 0.4 0.077 13.2 0.4 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain NodZ PF05830.11 OWF48136.1 - 0.033 13.0 0.0 7.7 5.2 0.0 2.7 3 0 0 3 3 3 0 Nodulation protein Z (NodZ) 7tm_1 PF00001.21 OWF48137.1 - 5.7e-11 42.2 23.1 7.4e-11 41.9 23.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF48137.1 - 5.9e-05 22.5 28.1 0.0021 17.4 5.4 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DDE_Tnp_4 PF13359.6 OWF48138.1 - 7.6e-19 67.9 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OWF48138.1 - 6.9e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain DUF1161 PF06649.12 OWF48138.1 - 0.022 14.9 0.3 0.077 13.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) partial_CstF PF15861.5 OWF48138.1 - 0.027 14.3 0.7 0.056 13.2 0.7 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DDE_Tnp_1_2 PF13586.6 OWF48138.1 - 0.095 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain zf-CCHC PF00098.23 OWF48139.1 - 0.0045 17.0 11.6 0.0065 16.5 3.2 2.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 OWF48139.1 - 0.068 13.1 0.3 0.068 13.1 0.3 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OWF48139.1 - 1.6 8.6 5.1 2.1 8.1 0.5 2.2 2 0 0 2 2 2 0 Zinc knuckle Kelch_6 PF13964.6 OWF48140.1 - 2e-41 139.0 1.7 1.7e-07 31.3 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 OWF48140.1 - 1e-40 137.0 2.9 5.3e-07 29.1 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OWF48140.1 - 3.9e-40 135.6 9.1 5e-07 29.6 0.0 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF48140.1 - 6.3e-37 124.2 9.1 5.3e-08 32.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 OWF48140.1 - 3.7e-35 119.3 2.8 1.3e-05 25.0 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OWF48140.1 - 1.4e-29 101.8 2.3 3e-07 30.6 0.1 7.5 7 1 0 7 7 7 5 Galactose oxidase, central domain Ank_2 PF12796.7 OWF48141.1 - 4.5e-42 142.5 0.0 1.8e-13 50.9 0.0 5.7 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48141.1 - 2e-35 120.7 6.4 2.2e-07 31.3 0.0 7.0 5 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF48141.1 - 7.5e-29 98.9 1.6 6.6e-05 23.2 0.1 9.2 8 1 1 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 OWF48141.1 - 3.1e-26 88.5 3.4 0.0017 18.6 0.0 9.3 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OWF48141.1 - 3.9e-26 90.8 6.4 2.3e-06 27.8 0.0 7.5 4 2 4 8 8 8 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF48141.1 - 2.6e-05 24.5 0.0 6.8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 SOCS box Imm_superinfect PF14373.6 OWF48141.1 - 0.16 11.9 0.1 16 5.6 0.0 4.0 5 0 0 5 5 5 0 Superinfection immunity protein SART-1 PF03343.13 OWF48142.1 - 3.5e-149 498.3 62.2 3.5e-149 498.3 62.2 2.0 2 0 0 2 2 2 1 SART-1 family HYR PF02494.16 OWF48143.1 - 1.3e-18 67.1 1.1 1.9e-14 53.8 0.1 2.7 2 0 0 2 2 2 2 HYR domain Ephrin_rec_like PF07699.13 OWF48143.1 - 2.1e-14 53.0 36.4 9.5e-09 34.9 10.8 4.6 3 1 1 4 4 4 3 Putative ephrin-receptor like TSP_1 PF00090.19 OWF48143.1 - 1.3e-11 44.6 11.0 1.3e-11 44.6 11.0 4.0 3 0 0 3 3 3 1 Thrombospondin type 1 domain EGF PF00008.27 OWF48143.1 - 3.5e-10 40.0 28.1 3.9e-05 23.8 9.9 4.6 2 0 0 2 2 2 2 EGF-like domain Sushi PF00084.20 OWF48143.1 - 0.00015 22.3 6.2 0.00015 22.3 6.2 6.5 6 2 2 8 8 8 2 Sushi repeat (SCR repeat) hEGF PF12661.7 OWF48143.1 - 0.00018 22.0 25.9 0.0072 16.9 6.9 5.5 3 0 0 3 3 3 2 Human growth factor-like EGF DUF1269 PF06897.12 OWF48143.1 - 4.1 7.8 5.8 9.4 6.6 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Ephrin_rec_like PF07699.13 OWF48144.1 - 4.2e-15 55.2 15.9 1.4e-09 37.5 4.7 4.6 3 1 1 4 4 4 3 Putative ephrin-receptor like Sushi PF00084.20 OWF48144.1 - 4.3e-14 52.8 31.1 1.8e-07 31.6 4.2 4.6 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) HYR PF02494.16 OWF48144.1 - 2.3e-13 50.3 0.0 7.4e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 HYR domain TSP_1 PF00090.19 OWF48144.1 - 4.1e-13 49.3 6.8 4.1e-13 49.3 6.8 4.1 3 0 0 3 3 3 1 Thrombospondin type 1 domain EGF PF00008.27 OWF48144.1 - 6.5e-09 35.9 28.3 3e-05 24.2 6.4 4.9 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 OWF48144.1 - 0.0084 16.7 29.7 0.062 14.0 7.7 5.5 4 0 0 4 4 4 2 Human growth factor-like EGF Laminin_G_3 PF13385.6 OWF48144.1 - 0.011 15.8 0.2 0.02 15.0 0.2 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF5011 PF16403.5 OWF48144.1 - 0.045 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) Big_3_4 PF13754.6 OWF48144.1 - 0.092 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function Abhydrolase_1 PF00561.20 OWF48145.1 - 2.9e-22 79.6 0.0 7.6e-21 74.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF48145.1 - 2.3e-19 70.9 0.0 3.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF48145.1 - 7.8e-16 58.1 0.0 2.1e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OWF48145.1 - 0.00056 18.7 0.0 0.0025 16.6 0.0 2.0 2 1 1 3 3 3 1 Ndr family LIDHydrolase PF10230.9 OWF48145.1 - 0.0017 18.0 0.3 0.083 12.4 0.0 2.2 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF915 PF06028.11 OWF48145.1 - 0.025 13.9 0.1 0.075 12.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 OWF48145.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 OWF48145.1 - 0.068 12.9 0.1 0.9 9.2 0.0 2.6 3 0 0 3 3 3 0 PGAP1-like protein Thioesterase PF00975.20 OWF48145.1 - 0.068 13.3 0.1 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_5 PF12695.7 OWF48145.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Plasmid_parti PF01672.16 OWF48146.1 - 0.9 10.2 5.0 0.83 10.3 2.9 1.9 2 0 0 2 2 2 0 Putative plasmid partition protein IGFL PF14653.6 OWF48148.1 - 6 6.9 38.3 0.37 10.8 0.2 5.4 2 1 3 5 5 5 0 Insulin growth factor-like family zf-TRAF PF02176.18 OWF48149.1 - 4.1e-20 72.2 27.8 3.5e-12 46.8 6.4 4.2 1 1 3 4 4 4 4 TRAF-type zinc finger Sina PF03145.16 OWF48149.1 - 1.4e-08 35.0 24.7 0.0007 19.6 5.2 3.4 1 1 2 3 3 3 2 Seven in absentia protein family zf-TRAF_2 PF15965.5 OWF48149.1 - 6.2e-05 23.4 5.4 6.2e-05 23.4 5.4 3.4 3 1 1 4 4 3 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 OWF48149.1 - 0.0018 18.1 5.0 0.0064 16.3 5.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF48149.1 - 0.0067 16.3 2.9 0.0067 16.3 2.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF48149.1 - 0.0072 16.2 5.5 0.0072 16.2 5.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) A2L_zn_ribbon PF08792.10 OWF48149.1 - 0.025 14.3 0.4 0.025 14.3 0.4 2.7 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-RING_6 PF14835.6 OWF48149.1 - 0.19 11.6 5.3 0.28 11.1 1.3 3.0 3 0 0 3 3 3 0 zf-RING of BARD1-type protein FlaC_arch PF05377.11 OWF48149.1 - 0.68 10.4 3.0 4.9 7.6 0.2 3.1 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 OWF48149.1 - 3 8.4 6.5 16 6.0 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-RING_5 PF14634.6 OWF48149.1 - 4.3 7.4 12.7 0.1 12.6 5.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain RrnaAD PF00398.20 OWF48150.1 - 0.0014 17.8 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RdRP_3 PF00998.23 OWF48150.1 - 0.071 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase AAR2 PF05282.11 OWF48151.1 - 2e-112 376.1 0.0 2.3e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Pkinase PF00069.25 OWF48152.1 - 1.4e-143 477.0 0.0 1.4e-72 244.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF48152.1 - 1.7e-74 250.4 0.0 1.9e-38 132.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OWF48152.1 - 4.5e-12 45.8 0.0 1.3e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF48152.1 - 1.2e-10 41.2 0.0 0.00055 19.3 0.0 2.8 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OWF48152.1 - 4.4e-07 29.0 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 OWF48152.1 - 7e-07 29.4 0.1 0.083 12.8 0.0 3.4 3 0 0 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OWF48152.1 - 2.4e-05 24.0 0.1 0.013 15.0 0.0 2.8 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL Pkinase_C PF00433.24 OWF48152.1 - 3e-05 24.6 3.7 0.00011 22.9 3.7 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OWF48152.1 - 0.00013 21.1 0.1 0.012 14.6 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 OWF48152.1 - 0.00032 20.4 0.0 1.9 8.0 0.0 3.2 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OWF48152.1 - 0.012 15.2 0.2 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 RIO1 family Choline_kinase PF01633.20 OWF48152.1 - 0.18 11.3 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Neur_chan_LBD PF02931.23 OWF48153.1 - 2e-11 43.7 0.2 9.7e-11 41.5 0.1 1.8 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48153.1 - 0.077 13.0 1.1 0.13 12.3 1.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APG6_N PF17675.1 OWF48154.1 - 0.00054 20.5 6.1 0.0012 19.4 6.1 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region PRKG1_interact PF15898.5 OWF48154.1 - 0.00065 20.6 14.6 0.0022 18.9 11.5 3.0 2 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 OWF48154.1 - 0.00079 19.6 8.0 0.0016 18.6 8.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 OWF48154.1 - 0.0033 17.7 4.2 0.0033 17.7 4.2 2.0 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 OWF48154.1 - 0.0093 16.3 10.4 0.012 16.0 8.4 2.3 2 1 1 3 3 3 1 Csm1 N-terminal domain FAM76 PF16046.5 OWF48154.1 - 0.011 15.1 2.1 0.011 15.1 2.1 2.0 2 0 0 2 2 2 0 FAM76 protein SHE3 PF17078.5 OWF48154.1 - 0.021 14.6 14.6 0.024 14.3 12.7 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 CEP209_CC5 PF16574.5 OWF48154.1 - 0.025 14.7 7.5 0.026 14.7 6.0 1.7 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 Fib_alpha PF08702.10 OWF48154.1 - 0.028 14.6 0.4 0.065 13.4 0.4 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 OWF48154.1 - 0.032 14.0 8.4 0.063 13.1 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TPD52 PF04201.15 OWF48154.1 - 0.11 12.1 5.7 0.19 11.4 5.7 1.3 1 0 0 1 1 1 0 Tumour protein D52 family ART PF01129.18 OWF48154.1 - 0.31 10.3 1.6 5.3 6.3 1.6 2.1 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase YabA PF06156.13 OWF48154.1 - 0.47 11.1 7.2 0.24 12.1 4.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 OWF48154.1 - 5 4.9 5.4 7.3 4.4 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAT1-1-2 PF17043.5 OWF48155.1 - 0.062 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function MFS_1 PF07690.16 OWF48156.1 - 1.7e-27 96.3 17.1 1.7e-27 96.3 17.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Pentapeptide PF00805.22 OWF48156.1 - 0.00029 20.4 14.2 1.3e+02 2.3 0.0 10.0 2 1 8 13 13 13 0 Pentapeptide repeats (8 copies) DUF3413 PF11893.8 OWF48156.1 - 1.9 7.6 6.3 0.25 10.5 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) SNF PF00209.18 OWF48157.1 - 1.7e-162 541.8 33.5 2e-162 541.6 33.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family OST3_OST6 PF04756.13 OWF48157.1 - 0.27 10.5 0.0 0.27 10.5 0.0 3.0 3 1 0 3 3 3 0 OST3 / OST6 family, transporter family IgGFc_binding PF17517.2 OWF48158.1 - 2.1e-22 79.7 0.0 2.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 IgGFc binding protein PND PF17949.1 OWF48158.1 - 0.048 13.9 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 FANCM pseudonuclease domain DUF445 PF04286.12 OWF48159.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Phage_holin_6_1 PF09682.10 OWF48159.1 - 0.0018 18.7 0.3 1e+02 3.4 0.0 5.3 3 1 2 5 5 5 0 Bacteriophage holin of superfamily 6 (Holin_LLH) SSPI PF14098.6 OWF48159.1 - 0.015 15.5 11.1 24 5.2 0.1 6.5 2 1 5 7 7 7 0 Small, acid-soluble spore protein I RHH_6 PF16762.5 OWF48159.1 - 0.022 15.4 2.8 13 6.4 0.1 4.8 1 1 6 7 7 7 0 Ribbon-helix-helix domain DUF4681 PF15732.5 OWF48159.1 - 0.34 11.2 10.2 6.4 7.1 0.2 4.3 1 1 4 5 5 5 0 Domain of unknown function (DUF4681) OCRE PF17780.1 OWF48159.1 - 0.5 10.4 2.2 10 6.2 0.1 3.7 3 1 2 5 5 5 0 OCRE domain MIP PF00230.20 OWF48161.1 - 3.6e-61 206.8 4.7 4.7e-61 206.4 4.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein AdoHcyase PF05221.17 OWF48162.1 - 2.4e-135 450.5 0.0 3e-131 437.0 0.0 2.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OWF48162.1 - 3.4e-83 277.6 0.9 6.3e-83 276.7 0.9 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OWF48162.1 - 5.2e-09 35.7 0.2 9.1e-09 34.9 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OWF48162.1 - 8.6e-07 28.7 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OWF48162.1 - 0.0075 16.5 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 OWF48162.1 - 0.015 15.7 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 OWF48162.1 - 0.025 13.9 0.2 0.1 11.9 0.2 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 OWF48162.1 - 0.027 14.6 0.2 0.048 13.7 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 OWF48162.1 - 0.073 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase vATP-synt_AC39 PF01992.16 OWF48163.1 - 4.4e-114 381.5 0.2 4.9e-114 381.3 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Lectin_C PF00059.21 OWF48164.1 - 2.4e-11 44.3 1.9 6e-11 43.0 1.9 1.7 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 OWF48164.1 - 4.7e-10 39.8 0.0 1.3e-09 38.3 0.0 1.8 2 0 0 2 2 1 1 CUB domain Shisa PF13908.6 OWF48164.1 - 0.001 19.4 0.1 0.0017 18.6 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF48164.1 - 0.0041 18.0 0.1 0.011 16.6 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.13 OWF48164.1 - 0.018 13.7 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Tweety UL45 PF05473.12 OWF48164.1 - 0.023 14.3 0.1 0.053 13.1 0.1 1.7 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like SIT PF15330.6 OWF48164.1 - 0.024 15.1 0.1 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT WBP-1 PF11669.8 OWF48164.1 - 0.027 15.1 0.0 0.057 14.1 0.0 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF4064 PF13273.6 OWF48164.1 - 0.037 14.3 0.8 0.073 13.4 0.0 1.9 3 0 0 3 3 2 0 Protein of unknown function (DUF4064) UL41A PF17591.2 OWF48164.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus UL41A Orthoreo_P10 PF07204.11 OWF48164.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DAG1 PF05454.11 OWF48164.1 - 0.17 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Adeno_E3_CR2 PF02439.15 OWF48164.1 - 0.27 11.0 3.7 0.56 10.0 3.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LSR PF05624.14 OWF48164.1 - 0.76 9.8 5.4 1.8 8.6 5.4 1.6 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) DUF4476 PF14771.6 OWF48165.1 - 2e-11 44.0 0.3 1.8e-07 31.4 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) LRR_8 PF13855.6 OWF48166.1 - 1.5e-06 27.8 0.3 0.0022 17.7 0.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF48166.1 - 0.00015 22.0 3.2 0.036 14.5 0.3 3.5 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF48166.1 - 0.00064 19.6 3.5 0.27 11.4 0.1 4.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 OWF48166.1 - 0.0043 17.4 2.9 49 5.1 0.0 5.9 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 OWF48167.1 - 4.7e-06 26.3 0.1 0.0048 16.6 0.0 3.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF48167.1 - 6.5e-06 26.4 0.7 0.0022 18.4 0.1 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRRCT PF01463.24 OWF48167.1 - 0.002 18.6 0.0 0.0055 17.2 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 OWF48167.1 - 0.028 14.9 4.1 3.6 8.5 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Ac110_PIF PF07280.11 OWF48167.1 - 0.035 13.9 3.6 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Per os infectivity factor AC110 LRR_6 PF13516.6 OWF48167.1 - 0.085 13.0 3.3 35 4.8 0.0 4.5 5 1 1 6 6 6 0 Leucine Rich repeat TIR PF01582.20 OWF48168.1 - 6.2e-19 68.5 0.2 9.8e-19 67.8 0.2 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF48168.1 - 2.5e-17 63.5 0.0 5.6e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF48168.1 - 5.4e-05 22.9 1.2 0.32 10.8 0.1 3.2 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF48168.1 - 6.8e-05 23.2 1.4 0.19 12.2 0.1 3.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF48168.1 - 0.00018 21.3 0.2 0.46 10.7 0.0 3.6 4 0 0 4 4 4 2 Leucine Rich repeat DUF1863 PF08937.11 OWF48168.1 - 0.0056 17.0 0.1 0.058 13.7 0.2 2.6 2 1 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) zf-UBR PF02207.20 OWF48168.1 - 0.029 14.5 0.1 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TMEM132D_C PF15706.5 OWF48168.1 - 0.29 10.9 1.0 0.61 9.9 0.2 1.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term HTH_21 PF13276.6 OWF48169.1 - 0.035 14.2 0.3 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 HTH-like domain Speriolin_C PF15059.6 OWF48169.1 - 0.048 13.8 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Speriolin C-terminus HTH_33 PF13592.6 OWF48169.1 - 0.1 12.3 1.0 3.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn helix 7tm_1 PF00001.21 OWF48171.1 - 6.6e-54 183.0 17.3 9.2e-54 182.5 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF48171.1 - 4.3e-12 46.0 14.7 4.3e-12 46.0 14.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF48171.1 - 5.4e-12 46.0 13.4 1.2e-11 44.9 13.4 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF48171.1 - 9.4e-10 38.6 19.8 2e-09 37.5 18.3 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF48171.1 - 4.4e-05 22.9 19.1 0.00018 20.9 19.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4731 PF15875.5 OWF48171.1 - 1.3 9.3 4.6 27 5.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) DUF973 PF06157.11 OWF48171.1 - 1.9 7.5 8.8 0.25 10.4 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF973) ShK PF01549.24 OWF48172.1 - 2.8e-16 59.8 62.0 1.6e-07 31.7 11.7 4.6 4 0 0 4 4 4 3 ShK domain-like VWC PF00093.18 OWF48172.1 - 0.00039 20.7 39.9 0.0028 17.9 16.5 5.0 5 0 0 5 5 5 2 von Willebrand factor type C domain fn1 PF00039.18 OWF48172.1 - 0.39 10.9 26.3 2.6 8.3 7.2 3.2 2 0 0 2 2 2 0 Fibronectin type I domain Peptidase_C1 PF00112.23 OWF48173.1 - 6.8e-48 163.6 9.3 9.1e-48 163.2 9.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OWF48173.1 - 0.00015 20.6 0.1 0.00057 18.8 0.4 1.6 2 0 0 2 2 2 1 Peptidase C1-like family Pkinase_Tyr PF07714.17 OWF48174.1 - 7.7e-54 182.7 0.0 3.7e-33 114.9 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OWF48174.1 - 3.9e-30 105.1 0.0 2.6e-20 72.9 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 OWF48174.1 - 0.044 13.1 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like adh_short_C2 PF13561.6 OWF48175.1 - 2.6e-55 187.5 0.0 3.2e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF48175.1 - 2.7e-47 160.7 0.0 3.3e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF48175.1 - 5e-07 29.8 0.1 4.3e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 KR domain DFP PF04127.15 OWF48175.1 - 0.0079 16.0 0.4 0.014 15.2 0.4 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Orn_Arg_deC_N PF02784.16 OWF48175.1 - 0.013 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain UCH_1 PF13423.6 OWF48175.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_10 PF00331.20 OWF48175.1 - 0.16 11.1 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyco_tran_WecB PF03808.13 OWF48175.1 - 0.18 11.7 0.1 0.28 11.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family adh_short_C2 PF13561.6 OWF48176.1 - 8.3e-57 192.4 0.0 1e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF48176.1 - 1.3e-48 165.1 0.3 1.6e-48 164.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF48176.1 - 5e-10 39.6 0.1 7.2e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 OWF48176.1 - 0.029 14.2 0.3 0.067 13.0 0.3 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein LBP_BPI_CETP_C PF02886.17 OWF48177.1 - 3.8e-32 111.7 3.2 2.9e-23 82.6 0.0 2.3 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 OWF48177.1 - 2.1e-26 92.5 0.0 2.9e-25 88.8 0.0 2.3 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain DUF3869 PF12985.7 OWF48177.1 - 0.19 12.1 0.7 0.73 10.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) C1q PF00386.21 OWF48178.1 - 5.4e-23 81.6 0.0 8e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF48178.1 - 0.00025 20.9 0.2 0.00042 20.2 0.2 1.3 1 0 0 1 1 1 1 BclA C-terminal domain ZapB PF06005.12 OWF48178.1 - 0.0043 17.5 2.4 0.0069 16.8 2.4 1.3 1 0 0 1 1 1 1 Cell division protein ZapB TMCO5 PF14992.6 OWF48178.1 - 0.0047 16.5 2.3 0.0068 16.0 2.3 1.1 1 0 0 1 1 1 1 TMCO5 family Leu_zip PF15294.6 OWF48178.1 - 0.006 16.1 0.2 0.0073 15.9 0.2 1.2 1 0 0 1 1 1 1 Leucine zipper TMF_DNA_bd PF12329.8 OWF48178.1 - 0.0079 16.2 2.0 0.011 15.7 2.0 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 OWF48178.1 - 0.021 15.1 0.2 0.042 14.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 OWF48178.1 - 0.025 13.5 0.7 0.035 13.0 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 OWF48178.1 - 0.026 14.7 1.3 0.04 14.1 1.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.8 OWF48178.1 - 0.032 13.6 2.2 0.046 13.1 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Csm1_N PF18504.1 OWF48178.1 - 0.035 14.4 1.4 0.063 13.6 1.4 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain ADIP PF11559.8 OWF48178.1 - 0.04 14.0 0.8 0.059 13.5 0.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 OWF48178.1 - 0.045 13.9 1.6 0.075 13.1 1.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor CEP209_CC5 PF16574.5 OWF48178.1 - 0.045 13.9 1.4 0.064 13.4 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 XhlA PF10779.9 OWF48178.1 - 0.054 13.7 0.4 0.14 12.4 0.4 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF724 PF05266.14 OWF48178.1 - 0.067 13.0 0.7 0.1 12.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 OWF48178.1 - 0.075 13.0 1.4 0.15 12.1 1.4 1.4 1 0 0 1 1 1 0 Laminin Domain II bZIP_2 PF07716.15 OWF48178.1 - 0.1 12.7 3.9 0.36 11.0 3.9 1.9 1 1 0 1 1 1 0 Basic region leucine zipper Cep57_CLD PF14073.6 OWF48178.1 - 0.11 12.5 3.1 0.16 12.0 3.1 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DivIC PF04977.15 OWF48178.1 - 0.2 11.5 0.7 0.35 10.7 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator LBP_BPI_CETP_C PF02886.17 OWF48179.1 - 3.1e-26 92.3 2.2 3.1e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 OWF48179.1 - 1.4e-21 76.8 0.0 3e-11 43.2 0.0 3.2 3 0 0 3 3 3 2 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP PF01273.25 OWF48180.1 - 9.4e-31 106.6 0.0 1.6e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 OWF48180.1 - 4.8e-27 94.9 0.1 1.5e-26 93.3 0.1 1.7 1 1 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain adh_short PF00106.25 OWF48181.1 - 9.2e-38 129.7 0.0 1.2e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF48181.1 - 5.7e-28 98.1 0.0 8.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF48181.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OWF48181.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding RRM_1 PF00076.22 OWF48182.1 - 2.5e-18 65.6 0.3 4.2e-18 64.9 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4878 PF12870.7 OWF48182.1 - 0.029 14.7 0.5 0.047 14.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) DUF4226 PF10774.9 OWF48182.1 - 0.044 14.1 0.2 0.081 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) RL PF17797.1 OWF48182.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RL domain DUF4140 PF13600.6 OWF48182.1 - 0.11 13.0 0.8 0.2 12.1 0.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Mab-21 PF03281.14 OWF48183.1 - 1e-31 110.3 0.2 1.7e-31 109.7 0.2 1.3 1 0 0 1 1 1 1 Mab-21 protein Polbeta PF18765.1 OWF48183.1 - 0.0016 18.4 0.1 0.005 16.9 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Mab-21 PF03281.14 OWF48185.1 - 7.1e-31 107.6 0.4 1.2e-30 106.9 0.4 1.3 1 0 0 1 1 1 1 Mab-21 protein Methyltransf_33 PF10017.9 OWF48186.1 - 1.5e-63 214.8 0.0 1.8e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_31 PF13847.6 OWF48186.1 - 0.056 13.2 0.1 0.23 11.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_33 PF10017.9 OWF48187.1 - 8.5e-61 205.8 0.0 1e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF2013 PF09431.10 OWF48187.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2013) Methyltransf_12 PF08242.12 OWF48187.1 - 0.14 12.9 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 OWF48188.1 - 2.6e-67 227.2 0.0 3e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Mab-21 PF03281.14 OWF48189.1 - 5.8e-32 111.2 0.0 7.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Dzip-like_N PF13815.6 OWF48189.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Methyltransf_33 PF10017.9 OWF48190.1 - 2.6e-60 204.2 0.1 3.3e-60 203.8 0.1 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent SNF PF00209.18 OWF48191.1 - 2.6e-140 468.6 35.9 3.6e-140 468.1 35.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CCDC53 PF10152.9 OWF48192.1 - 8.5 6.8 18.6 12 6.2 18.6 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex AA_permease_2 PF13520.6 OWF48193.1 - 1.6e-58 198.6 34.8 1.9e-58 198.3 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF48193.1 - 1e-19 70.6 29.8 1.7e-19 69.8 29.8 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OWF48194.1 - 1.3e-58 198.9 43.8 1.6e-58 198.5 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF48194.1 - 6.4e-27 94.3 40.3 1.3e-26 93.2 40.3 1.5 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 OWF48195.1 - 1.4e-12 47.2 34.8 1.7e-08 33.8 10.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 OWF48195.1 - 3.9e-11 42.9 7.1 3.9e-11 42.9 7.1 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Forkhead PF00250.18 OWF48196.1 - 3.1e-36 123.5 0.0 5.9e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain STE PF02200.16 OWF48197.1 - 0.015 15.7 0.9 2.3 8.7 0.2 3.4 1 1 1 2 2 2 0 STE like transcription factor DUF273 PF03314.14 OWF48197.1 - 5.2 6.6 14.0 8.2 5.9 1.4 3.2 1 1 1 2 2 2 0 Protein of unknown function, DUF273 DUF273 PF03314.14 OWF48198.1 - 0.16 11.5 23.5 2.9 7.4 2.8 4.4 1 1 5 6 6 6 0 Protein of unknown function, DUF273 DEC1 PF15859.5 OWF48198.1 - 0.29 11.2 13.9 21 5.2 0.7 6.0 1 1 6 7 7 7 0 Deleted in esophageal cancer 1 family DEC1 PF15859.5 OWF48199.1 - 0.00048 20.1 15.3 13 5.9 0.1 7.6 1 1 6 7 7 7 3 Deleted in esophageal cancer 1 family Baculo_p26 PF04766.12 OWF48199.1 - 0.01 15.4 0.2 2 7.8 0.0 3.9 1 1 3 4 4 4 1 Nucleopolyhedrovirus p26 protein DUF273 PF03314.14 OWF48199.1 - 0.043 13.4 24.9 1.4 8.4 2.9 5.2 1 1 4 5 5 5 0 Protein of unknown function, DUF273 Herpes_UL33 PF03581.13 OWF48199.1 - 0.15 12.4 1.6 41 4.6 0.6 3.6 1 1 1 2 2 2 0 Herpesvirus UL33-like protein DUF3658 PF12395.8 OWF48199.1 - 0.62 10.0 4.9 13 5.7 0.2 3.9 1 1 3 4 4 4 0 Protein of unknown function YccV-like PF08755.11 OWF48199.1 - 9.6 6.8 18.7 68 4.1 0.8 7.2 1 1 6 8 8 8 0 Hemimethylated DNA-binding protein YccV like DEC1 PF15859.5 OWF48200.1 - 0.0038 17.2 11.1 4.4 7.4 0.3 5.4 1 1 5 6 6 6 5 Deleted in esophageal cancer 1 family HU-CCDC81_bac_1 PF18174.1 OWF48200.1 - 4 7.4 5.0 43 4.1 0.1 3.4 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 1 DEC1 PF15859.5 OWF48201.1 - 0.29 11.2 4.4 10 6.2 1.0 3.2 1 1 1 2 2 2 0 Deleted in esophageal cancer 1 family CBP PF12192.8 OWF48201.1 - 3.3 8.0 8.6 46 4.3 5.4 3.0 1 1 2 3 3 3 0 Fungal calcium binding protein Thioredoxin PF00085.20 OWF48202.1 - 1.1e-15 57.5 0.2 3.3e-10 39.9 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OWF48202.1 - 4.5e-08 33.2 3.7 8.5e-08 32.3 1.9 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain ERp29 PF07749.12 OWF48202.1 - 2.3e-06 28.4 0.2 5e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 OWF48202.1 - 0.00019 20.9 0.6 0.0015 18.0 0.1 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family HyaE PF07449.11 OWF48202.1 - 0.0022 17.9 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 OWF48202.1 - 0.0028 18.1 2.1 0.36 11.3 1.2 3.5 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OWF48202.1 - 0.0082 16.4 3.0 1.6 9.1 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like Arrestin_C PF02752.22 OWF48204.1 - 7.4e-27 94.4 2.8 6.1e-24 85.0 0.0 3.5 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF48204.1 - 5.3e-22 78.5 1.3 3.2e-21 75.9 0.1 2.9 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain DUF1330 PF07045.11 OWF48204.1 - 9.4e-05 22.7 0.1 0.6 10.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) Macoilin PF09726.9 OWF48204.1 - 0.45 9.0 3.1 0.62 8.6 3.1 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 OWF48204.1 - 5.6 6.8 10.5 8.3 6.3 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 OWF48204.1 - 9.4 5.3 17.7 14 4.7 17.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PDZ PF00595.24 OWF48205.1 - 7.3e-12 45.5 0.1 1.2e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PB1 PF00564.24 OWF48205.1 - 1.6e-10 40.8 0.0 3.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PDZ_6 PF17820.1 OWF48205.1 - 1.2e-08 34.7 0.1 2.3e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SL4P PF17618.2 OWF48205.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein PDZ_2 PF13180.6 OWF48205.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain TPP1 PF10341.9 OWF48206.1 - 5.4e-07 29.6 0.0 1.7e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD ATG16 PF08614.11 OWF48207.1 - 8.5e-05 22.9 14.4 0.00011 22.5 14.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 OWF48207.1 - 0.00023 21.7 21.1 0.0058 17.2 12.7 2.5 1 1 1 2 2 2 1 SlyX Fib_alpha PF08702.10 OWF48207.1 - 0.00026 21.2 15.9 0.00038 20.7 15.9 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family OmpH PF03938.14 OWF48207.1 - 0.00041 20.7 8.5 0.00056 20.3 8.5 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.8 OWF48207.1 - 0.0012 18.8 13.3 0.0054 16.7 6.6 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 OWF48207.1 - 0.0014 19.2 5.7 0.0018 18.8 5.7 1.1 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 OWF48207.1 - 0.0038 16.2 13.5 0.0052 15.7 13.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 OWF48207.1 - 0.0038 16.4 11.0 0.0054 15.9 11.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 OWF48207.1 - 0.005 16.9 12.4 0.0077 16.3 12.4 1.1 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase WEMBL PF05701.11 OWF48207.1 - 0.0061 15.3 5.5 0.0078 15.0 5.5 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Gp58 PF07902.11 OWF48207.1 - 0.0068 14.8 25.1 0.012 14.0 22.8 1.5 1 1 0 1 1 1 1 gp58-like protein MAD PF05557.13 OWF48207.1 - 0.01 14.3 14.7 0.013 13.9 14.7 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Exonuc_VII_L PF02601.15 OWF48207.1 - 0.013 15.1 9.7 0.019 14.5 9.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 OWF48207.1 - 0.017 13.1 10.7 0.024 12.7 10.7 1.1 1 0 0 1 1 1 0 Prominin RskA PF10099.9 OWF48207.1 - 0.019 15.3 4.1 5.5 7.2 4.1 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FapA PF03961.13 OWF48207.1 - 0.02 13.6 4.9 0.025 13.2 4.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF148 PF02520.17 OWF48207.1 - 0.024 14.8 16.5 0.033 14.3 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 AIP3 PF03915.13 OWF48207.1 - 0.035 13.2 9.3 0.044 12.9 9.3 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4686 PF15742.5 OWF48207.1 - 0.036 13.2 18.5 0.051 12.7 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Tropomyosin PF00261.20 OWF48207.1 - 0.036 13.4 2.9 0.058 12.8 2.9 1.3 1 0 0 1 1 1 0 Tropomyosin Myosin_tail_1 PF01576.19 OWF48207.1 - 0.045 11.6 6.3 0.056 11.3 6.3 1.0 1 0 0 1 1 1 0 Myosin tail V_ATPase_I PF01496.19 OWF48207.1 - 0.048 11.6 3.8 0.061 11.2 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.13 OWF48207.1 - 0.051 13.3 18.0 0.07 12.8 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) YscO PF07321.12 OWF48207.1 - 0.051 13.5 9.2 0.072 13.0 9.2 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO TMPIT PF07851.13 OWF48207.1 - 0.068 12.4 11.7 0.087 12.1 11.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein HOOK PF05622.12 OWF48207.1 - 0.068 11.3 15.7 0.087 11.0 15.7 1.0 1 0 0 1 1 1 0 HOOK protein Bacillus_HBL PF05791.11 OWF48207.1 - 0.076 12.8 14.5 0.13 12.1 14.5 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF641 PF04859.12 OWF48207.1 - 0.078 13.3 10.1 0.42 11.0 10.0 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 OWF48207.1 - 0.081 13.0 12.3 0.44 10.6 12.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 OWF48207.1 - 0.082 12.7 14.3 0.26 11.1 6.7 2.1 1 1 1 2 2 2 0 USP8 interacting CENP-F_leu_zip PF10473.9 OWF48207.1 - 0.082 12.9 9.2 0.13 12.3 9.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 OWF48207.1 - 0.082 13.0 13.4 0.3 11.2 4.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ERM PF00769.19 OWF48207.1 - 0.095 12.5 10.5 0.18 11.6 10.5 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.6 OWF48207.1 - 0.096 12.0 11.4 0.13 11.6 11.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 OWF48207.1 - 0.096 11.6 2.8 0.13 11.2 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein YscO-like PF16789.5 OWF48207.1 - 0.11 12.6 4.0 0.15 12.1 4.0 1.1 1 0 0 1 1 1 0 YscO-like protein FliJ PF02050.16 OWF48207.1 - 0.12 12.6 22.1 0.24 11.6 22.1 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein Tropomyosin_1 PF12718.7 OWF48207.1 - 0.13 12.5 9.8 0.18 11.9 9.8 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF3552 PF12072.8 OWF48207.1 - 0.13 11.6 6.4 0.21 11.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) EzrA PF06160.12 OWF48207.1 - 0.14 10.3 9.5 0.19 9.9 9.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 OWF48207.1 - 0.14 12.2 16.7 0.21 11.6 16.7 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3972 PF13118.6 OWF48207.1 - 0.14 12.6 5.6 0.31 11.5 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) Folliculin PF11704.8 OWF48207.1 - 0.15 12.0 4.2 0.25 11.2 4.2 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Lebercilin PF15619.6 OWF48207.1 - 0.17 11.6 12.7 0.3 10.7 12.7 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SKA1 PF07160.12 OWF48207.1 - 0.2 11.5 13.9 0.15 11.9 8.6 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4449 PF14613.6 OWF48207.1 - 0.22 11.6 5.5 0.32 11.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF724 PF05266.14 OWF48207.1 - 0.25 11.2 6.2 0.35 10.7 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAM76 PF16046.5 OWF48207.1 - 0.27 10.6 8.1 0.47 9.8 8.1 1.3 1 0 0 1 1 1 0 FAM76 protein Baculo_PEP_C PF04513.12 OWF48207.1 - 0.33 11.0 22.1 0.74 9.9 3.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 OWF48207.1 - 0.41 9.9 12.5 1.1 8.6 12.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 OWF48207.1 - 0.43 11.1 19.1 1.6 9.2 19.1 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3450 PF11932.8 OWF48207.1 - 0.45 9.8 19.5 0.78 9.0 19.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 OWF48207.1 - 0.46 9.4 16.3 0.64 8.9 16.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 UPF0242 PF06785.11 OWF48207.1 - 0.52 10.4 18.5 1.7 8.7 18.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 OWF48207.1 - 0.63 10.0 17.5 0.81 9.6 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF812 PF05667.11 OWF48207.1 - 0.65 8.8 13.1 0.87 8.4 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.21 OWF48207.1 - 0.72 9.4 13.9 1.5 8.3 13.9 1.4 1 1 0 1 1 1 0 Intermediate filament protein Syntaxin-6_N PF09177.11 OWF48207.1 - 0.76 10.4 9.0 1.2 9.7 9.0 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal XhlA PF10779.9 OWF48207.1 - 0.82 9.9 5.2 2.6 8.3 1.4 2.4 1 1 1 2 2 2 0 Haemolysin XhlA Phage_GPO PF05929.11 OWF48207.1 - 0.84 9.2 10.8 0.47 10.0 9.0 1.4 2 0 0 2 2 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1151 PF06625.11 OWF48207.1 - 0.88 9.5 9.9 1.3 8.9 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) HrpB7 PF09486.10 OWF48207.1 - 0.89 9.9 8.5 1.4 9.2 2.5 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG5 PF10392.9 OWF48207.1 - 0.93 9.7 11.1 1.6 8.9 11.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 BST2 PF16716.5 OWF48207.1 - 0.97 10.1 22.2 0.14 12.8 15.9 2.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 OWF48207.1 - 1 9.9 21.9 3.6 8.1 12.9 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 OWF48207.1 - 1.2 9.5 10.5 2 8.8 10.5 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2570 PF10828.8 OWF48207.1 - 1.2 9.0 16.6 2.4 8.0 16.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Spectrin PF00435.21 OWF48207.1 - 1.2 9.6 11.6 4.5 7.8 11.5 1.8 1 1 1 2 2 2 0 Spectrin repeat CENP-H PF05837.12 OWF48207.1 - 1.6 9.2 12.9 2.7 8.5 12.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 OWF48207.1 - 2.4 8.6 11.9 2.9 8.4 2.9 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CC2-LZ PF16516.5 OWF48207.1 - 2.4 8.6 11.0 1.9 8.9 3.2 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Peptidase_M61 PF05299.12 OWF48207.1 - 2.9 8.3 7.4 9.8 6.6 7.4 1.8 1 1 0 1 1 1 0 M61 glycyl aminopeptidase CALCOCO1 PF07888.11 OWF48207.1 - 3.2 6.5 16.2 6.1 5.6 16.2 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 OWF48207.1 - 4 7.5 20.1 9.3 6.3 20.2 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 OWF48207.1 - 4.3 7.3 16.0 12 5.9 14.5 1.8 1 1 0 1 1 1 0 Laminin Domain II Vps51 PF08700.11 OWF48207.1 - 4.5 7.4 15.3 4.3 7.5 10.8 2.4 1 1 1 2 2 2 0 Vps51/Vps67 DUF4795 PF16043.5 OWF48207.1 - 6.6 6.3 13.7 21 4.6 13.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4094 PF13334.6 OWF48207.1 - 7.9 7.0 14.6 18 5.9 7.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TRAF_BIRC3_bd PF16673.5 OWF48207.1 - 8.3 6.3 7.7 4.9 7.0 1.7 2.1 1 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF2730 PF10805.8 OWF48207.1 - 9.4 6.4 7.2 13 5.9 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) M_domain PF12938.7 OWF48209.1 - 0.00067 19.5 0.5 0.00081 19.3 0.5 1.3 1 0 0 1 1 1 1 M domain of GW182 Tropomyosin PF00261.20 OWF48209.1 - 0.0044 16.4 0.4 0.0057 16.0 0.4 1.1 1 0 0 1 1 1 1 Tropomyosin DivIVA PF05103.13 OWF48209.1 - 0.0048 17.0 0.1 0.0062 16.6 0.1 1.1 1 0 0 1 1 1 1 DivIVA protein CENP-F_leu_zip PF10473.9 OWF48209.1 - 0.0063 16.5 1.0 0.0081 16.2 1.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WxL PF13731.6 OWF48209.1 - 0.0082 16.2 0.1 0.0087 16.1 0.1 1.1 1 0 0 1 1 1 1 WxL domain surface cell wall-binding CALCOCO1 PF07888.11 OWF48209.1 - 0.011 14.7 3.9 0.013 14.4 3.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.8 OWF48209.1 - 0.011 15.7 4.2 0.015 15.2 4.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 OWF48209.1 - 0.02 15.1 4.5 0.026 14.8 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 OWF48209.1 - 0.022 14.9 1.5 0.029 14.5 1.5 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.9 OWF48209.1 - 0.023 14.9 1.2 0.034 14.4 1.2 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 OWF48209.1 - 0.044 14.0 2.3 0.066 13.4 2.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 OWF48209.1 - 0.069 13.6 2.4 0.1 13.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 RskA PF10099.9 OWF48209.1 - 0.08 13.2 0.3 0.1 12.9 0.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Gp58 PF07902.11 OWF48209.1 - 0.087 11.1 3.3 0.11 10.8 3.3 1.0 1 0 0 1 1 1 0 gp58-like protein Tup_N PF08581.10 OWF48209.1 - 0.091 13.1 1.7 0.15 12.4 1.7 1.2 1 0 0 1 1 1 0 Tup N-terminal SlyX PF04102.12 OWF48209.1 - 0.15 12.7 9.1 0.28 11.8 3.6 1.9 1 1 1 2 2 2 0 SlyX DUF3450 PF11932.8 OWF48209.1 - 0.29 10.4 5.5 0.38 10.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 OWF48209.1 - 0.33 11.4 5.5 0.71 10.4 5.4 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 OWF48209.1 - 0.45 10.4 13.1 1.8 8.5 1.6 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5089 PF17002.5 OWF48210.1 - 0.011 15.6 1.9 0.014 15.2 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) DUF16 PF01519.16 OWF48210.1 - 0.094 13.2 0.9 0.13 12.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 COG2 PF06148.11 OWF48210.1 - 0.1 12.7 0.2 0.13 12.3 0.2 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-H2C2_5 PF13909.6 OWF48211.1 - 1.7e-46 155.6 280.0 4.7e-06 26.2 0.8 30.8 32 0 0 32 32 32 20 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OWF48211.1 - 1.5e-17 63.0 286.0 0.00041 20.7 1.7 31.6 32 0 0 32 32 32 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF48211.1 - 1.6e-07 31.6 280.2 0.0045 17.7 1.3 33.0 33 0 0 33 33 33 15 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF48211.1 - 7.5e-07 29.3 3.3 7.5e-07 29.3 3.3 39.1 43 2 0 43 43 43 13 Zinc-finger double domain zf-Di19 PF05605.12 OWF48211.1 - 0.0015 18.7 0.9 0.0015 18.7 0.9 19.8 21 1 1 22 22 22 9 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OWF48211.1 - 0.0077 16.0 0.6 0.0077 16.0 0.6 10.1 10 0 0 10 10 10 2 zinc-finger C2H2-type ARS2 PF04959.13 OWF48211.1 - 0.11 12.8 6.9 1.4 9.3 0.0 4.5 4 0 0 4 4 4 0 Arsenite-resistance protein 2 GAGA PF09237.11 OWF48211.1 - 2.2 8.2 0.0 2.2 8.2 0.0 5.2 6 0 0 6 6 6 0 GAGA factor PhnA_Zn_Ribbon PF08274.12 OWF48211.1 - 7.4 6.6 0.0 7.4 6.6 0.0 7.9 9 1 0 9 9 9 0 PhnA Zinc-Ribbon p450 PF00067.22 OWF48212.1 - 2e-112 376.3 0.0 2.3e-112 376.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tyrosinase PF00264.20 OWF48214.1 - 1e-33 117.5 4.5 6.1e-17 62.7 0.0 2.8 2 1 1 3 3 3 2 Common central domain of tyrosinase Peptidase_S8 PF00082.22 OWF48216.1 - 5.9e-38 130.8 0.0 8.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family ABC_transp_aux PF09822.9 OWF48216.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 ABC-type uncharacterized transport system HEAT PF02985.22 OWF48217.1 - 1.1e-12 47.0 1.5 0.056 13.7 0.0 7.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 OWF48217.1 - 1.4e-10 41.4 0.7 0.038 14.4 0.1 7.0 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 OWF48217.1 - 2.9e-09 37.2 7.4 0.35 11.4 0.1 8.4 8 0 0 8 8 8 2 HEAT-like repeat IFRD PF05004.13 OWF48217.1 - 2.8e-06 26.7 5.1 0.0025 17.0 0.0 5.2 5 0 0 5 5 5 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 OWF48217.1 - 3.2e-05 24.0 14.6 1.9 8.5 0.1 8.0 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Ecm29 PF13001.7 OWF48217.1 - 0.0011 17.7 6.8 0.11 11.1 0.1 4.6 5 0 0 5 5 5 2 Proteasome stabiliser Cohesin_HEAT PF12765.7 OWF48217.1 - 0.036 14.4 0.3 3.2 8.1 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 OWF48217.1 - 0.15 12.1 0.7 46 4.2 0.1 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OWF48217.1 - 0.2 11.2 6.4 9.9 5.6 0.3 5.2 5 0 0 5 5 5 0 CLASP N terminal HeH PF12949.7 OWF48218.1 - 0.0031 17.2 0.1 0.0062 16.2 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Ish1 PF10281.9 OWF48218.1 - 0.038 14.3 0.3 0.11 12.8 0.3 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF4708 PF15813.5 OWF48219.1 - 1.4e-71 240.8 0.7 1.7e-71 240.6 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) ketoacyl-synt PF00109.26 OWF48220.1 - 1.9e-46 158.7 0.0 3.8e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OWF48220.1 - 9.8e-30 103.0 0.0 1.9e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 OWF48220.1 - 1.4e-19 71.1 0.1 5.8e-18 65.8 0.1 2.5 1 1 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 OWF48220.1 - 2.8e-18 66.4 0.0 7.5e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 OWF48220.1 - 0.026 13.9 0.2 0.078 12.3 0.1 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain TRP_2 PF08344.11 OWF48221.1 - 3.9e-25 87.8 0.9 1.1e-24 86.4 0.9 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 OWF48221.1 - 3e-20 72.5 18.0 3e-20 72.5 18.0 1.7 2 0 0 2 2 2 1 Ion transport protein Ank_2 PF12796.7 OWF48221.1 - 1.2e-11 45.0 0.3 6.1e-07 29.9 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48221.1 - 2.2e-09 37.6 0.2 3.8e-05 24.2 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF48221.1 - 2.7e-07 30.4 0.3 0.8 10.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OWF48221.1 - 1.5e-06 28.4 0.0 0.31 11.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OWF48221.1 - 5.4e-06 26.6 0.1 0.09 13.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 OWF48221.1 - 0.0074 15.0 11.0 0.028 13.1 0.1 2.9 3 0 0 3 3 3 2 Polycystin cation channel SUR7 PF06687.12 OWF48221.1 - 0.014 15.0 1.1 0.014 15.0 1.1 2.2 2 1 1 3 3 3 0 SUR7/PalI family DSPc PF00782.20 OWF48222.1 - 1.8e-21 76.3 0.1 2.3e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF48222.1 - 2.6e-06 27.6 0.1 3.9e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OWF48222.1 - 3.9e-05 23.3 0.4 8.3e-05 22.3 0.4 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 OWF48222.1 - 0.00018 21.1 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 OWF48222.1 - 0.0034 17.8 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase3 PF13350.6 OWF48222.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family RNA_pol_Rpb2_4 PF04566.13 OWF48222.1 - 0.079 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 ETF PF01012.21 OWF48223.1 - 7.5e-46 156.3 0.3 9.4e-46 156.0 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Meis_PKNOX_N PF16493.5 OWF48224.1 - 8.7e-38 128.6 1.1 1.7e-37 127.6 1.1 1.5 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 OWF48224.1 - 7.2e-19 67.4 2.1 1.5e-18 66.4 2.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF48224.1 - 4.3e-08 32.9 0.4 9.1e-08 31.8 0.4 1.5 1 0 0 1 1 1 1 Homeodomain Cwf_Cwc_15 PF04889.12 OWF48224.1 - 0.11 12.2 5.4 0.19 11.4 5.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TIG PF01833.24 OWF48225.1 - 2.7e-122 399.1 119.0 9.2e-12 44.9 2.1 17.1 17 0 0 17 17 17 14 IPT/TIG domain G8 PF10162.9 OWF48225.1 - 1.2e-57 193.3 1.0 6.4e-31 107.0 0.4 3.2 2 0 0 2 2 2 2 G8 domain SRCR PF00530.18 OWF48225.1 - 1.2e-25 89.9 2.4 1.8e-25 89.3 0.5 2.5 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Beta_helix PF13229.6 OWF48225.1 - 2.3e-05 24.3 16.1 0.0002 21.2 6.2 7.7 5 2 1 7 7 7 3 Right handed beta helix region PA14 PF07691.12 OWF48225.1 - 0.00033 20.5 0.1 0.0019 18.0 0.1 2.4 1 0 0 1 1 1 1 PA14 domain AIG1 PF04548.16 OWF48226.1 - 3.3e-56 190.0 0.9 4.3e-56 189.6 0.9 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF48226.1 - 7.3e-11 42.2 0.0 1.8e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF48226.1 - 8.6e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OWF48226.1 - 1.2e-05 25.4 6.0 0.0034 17.5 0.0 3.7 3 2 2 5 5 5 2 Dynamin family RsgA_GTPase PF03193.16 OWF48226.1 - 0.0011 18.9 0.7 0.011 15.7 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OWF48226.1 - 0.007 15.7 0.7 0.021 14.1 0.1 1.9 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 OWF48226.1 - 0.01 16.3 0.8 0.022 15.3 0.6 1.9 1 1 0 1 1 1 0 ABC transporter IIGP PF05049.13 OWF48226.1 - 0.02 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GBP PF02263.19 OWF48226.1 - 0.026 13.8 0.5 0.053 12.8 0.0 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain RNA_helicase PF00910.22 OWF48226.1 - 0.028 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase tRNA_lig_kinase PF08303.11 OWF48226.1 - 0.036 14.2 2.4 0.086 12.9 2.3 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_22 PF13401.6 OWF48226.1 - 0.036 14.3 0.5 0.33 11.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 OWF48226.1 - 0.04 13.3 0.4 0.076 12.4 0.1 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit bPH_1 PF08000.11 OWF48226.1 - 0.11 12.5 0.4 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial PH domain TSP9 PF11493.8 OWF48226.1 - 0.22 12.2 2.5 0.36 11.5 0.1 2.5 2 1 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Cu-oxidase_3 PF07732.15 OWF48227.1 - 7.5e-39 132.4 0.6 2.2e-36 124.5 0.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF48227.1 - 1.8e-35 121.6 3.4 1.3e-31 109.2 0.4 3.8 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF48227.1 - 4.4e-26 91.9 0.0 4.7e-24 85.3 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.16 OWF48230.1 - 5.4e-37 127.5 28.0 5.4e-37 127.5 28.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OWF48230.1 - 7.9e-09 34.3 21.2 0.001 17.4 1.1 4.1 2 2 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OWF48230.1 - 9.7e-08 31.0 28.2 3.9e-06 25.7 15.9 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 OWF48230.1 - 5.2e-07 28.9 27.0 1.8e-05 23.8 25.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF48231.1 - 2.4e-39 135.3 24.1 2.4e-39 135.3 24.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF48231.1 - 1.1e-15 57.5 9.3 1.1e-15 57.5 9.3 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OWF48231.1 - 8.7e-15 54.0 18.8 6.8e-07 27.9 0.6 3.8 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OWF48231.1 - 4.1e-07 28.9 23.5 0.0003 19.5 4.6 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 OWF48231.1 - 0.0092 14.9 7.8 0.082 11.8 0.0 3.5 2 1 2 4 4 4 2 MFS_1 like family Tom5 PF10642.9 OWF48231.1 - 1 9.4 4.1 0.32 11.1 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase YdjC PF04794.12 OWF48232.1 - 1.7e-55 188.6 0.0 2.2e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein DSPc PF00782.20 OWF48233.1 - 9.9e-36 122.5 0.1 2.7e-35 121.1 0.1 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 OWF48233.1 - 1.9e-10 40.5 4.9 5e-10 39.2 4.9 1.8 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 OWF48233.1 - 0.00064 19.4 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GGGtGRT PF14057.6 OWF48233.1 - 0.18 10.7 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 GGGtGRT protein UPF0231 PF06062.11 OWF48233.1 - 0.27 11.5 1.5 0.55 10.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Dpy-30 PF05186.13 OWF48234.1 - 7.1e-05 22.4 0.2 0.031 14.0 0.0 2.7 2 0 0 2 2 2 2 Dpy-30 motif GAF PF01590.26 OWF48234.1 - 0.00034 21.3 0.0 0.0012 19.4 0.0 1.9 2 0 0 2 2 2 1 GAF domain EF-hand_6 PF13405.6 OWF48234.1 - 0.00049 19.8 0.3 0.056 13.4 0.1 4.1 4 0 0 4 4 4 1 EF-hand domain GAF_2 PF13185.6 OWF48234.1 - 0.00069 19.9 0.0 0.015 15.6 0.0 2.6 2 0 0 2 2 2 1 GAF domain EF-hand_7 PF13499.6 OWF48234.1 - 0.0034 17.8 9.1 0.0086 16.5 0.7 4.5 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF48234.1 - 0.0082 15.6 0.3 0.13 11.9 0.2 3.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF48234.1 - 0.092 12.6 0.6 0.56 10.1 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair PHR PF08005.12 OWF48235.1 - 3.4e-22 79.8 0.1 8.8e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 PHR domain BTB PF00651.31 OWF48235.1 - 2.6e-20 72.7 0.0 6.6e-20 71.4 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF48235.1 - 4.1e-14 52.5 2.1 2e-13 50.3 1.3 2.6 2 1 0 2 2 2 1 BTB And C-terminal Kelch Bacillus_HBL PF05791.11 OWF48235.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) BTB PF00651.31 OWF48237.1 - 1e-19 70.8 0.1 2.7e-19 69.5 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain PHR PF08005.12 OWF48237.1 - 2.3e-19 70.6 0.0 6.6e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 PHR domain BACK PF07707.15 OWF48237.1 - 2.8e-12 46.6 0.0 1.5e-11 44.3 0.1 2.2 3 0 0 3 3 3 1 BTB And C-terminal Kelch Sulfotransfer_1 PF00685.27 OWF48238.1 - 1.1e-49 169.4 3.7 4.6e-48 164.0 3.7 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF48238.1 - 4e-05 24.1 0.0 0.0011 19.4 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family Glyco_hydro_2_C PF02836.17 OWF48239.1 - 2.3e-40 138.6 0.0 3.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OWF48239.1 - 3.9e-20 72.4 0.3 1.7e-19 70.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OWF48239.1 - 1e-07 32.6 0.0 3.8e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OWF48239.1 - 0.025 15.2 0.1 0.066 13.8 0.1 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain FCP1_C PF09309.10 OWF48240.1 - 0.064 13.1 3.9 0.093 12.6 0.5 2.0 1 1 1 2 2 2 0 FCP1, C-terminal Lectin_C PF00059.21 OWF48241.1 - 6.3e-05 23.7 5.9 8.1e-05 23.3 5.9 1.1 1 0 0 1 1 1 1 Lectin C-type domain BTB PF00651.31 OWF48242.1 - 3.6e-15 56.2 0.6 9.1e-15 54.8 0.6 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 OWF48242.1 - 2.8e-09 36.9 84.4 0.00018 21.8 0.3 11.2 11 0 0 11 11 11 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF48242.1 - 1e-05 25.9 83.4 0.056 14.3 3.7 10.9 11 0 0 11 11 11 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF48242.1 - 1.4e-05 25.3 74.3 0.0029 17.9 1.0 10.3 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF48242.1 - 0.0016 18.3 31.1 0.019 15.0 0.1 7.5 7 0 0 7 7 7 2 C2H2-type zinc finger zf-met PF12874.7 OWF48242.1 - 3.3 8.2 42.4 0.43 11.0 2.9 7.7 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Na_sulph_symp PF00939.19 OWF48243.1 - 2.1e-37 129.3 9.5 2.4e-37 129.1 9.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF48243.1 - 1.5e-13 50.6 18.2 3e-13 49.6 18.1 1.6 1 1 0 1 1 1 1 Citrate transporter DUF565 PF04483.12 OWF48243.1 - 0.58 10.7 3.5 5.2 7.7 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF565) DUF1029 PF06269.12 OWF48243.1 - 0.64 10.2 6.5 1.6 8.9 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1029) DUF4728 PF15860.5 OWF48243.1 - 6.8 7.4 10.7 2.7 8.7 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4728) Na_sulph_symp PF00939.19 OWF48244.1 - 1.5e-54 185.8 1.0 1.8e-54 185.5 1.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF48244.1 - 4.6e-21 75.3 13.4 4e-16 59.1 9.0 2.3 2 0 0 2 2 2 2 Citrate transporter Lectin_C PF00059.21 OWF48245.1 - 3.6e-07 30.9 0.0 5.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain MANEC PF07502.14 OWF48245.1 - 0.055 13.7 1.9 0.36 11.1 0.4 2.5 2 1 0 2 2 2 0 MANEC domain CBM_14 PF01607.24 OWF48246.1 - 9.3e-20 70.5 20.3 4.3e-10 39.6 5.5 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain VWA PF00092.28 OWF48246.1 - 1.1e-08 35.5 0.0 1.6e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-TAZ PF02135.16 OWF48246.1 - 0.98 9.9 4.6 0.48 10.9 2.1 1.7 2 0 0 2 2 2 0 TAZ zinc finger RRM_1 PF00076.22 OWF48247.1 - 9.3e-17 60.6 0.0 1.9e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.7 OWF48247.1 - 1.6e-10 41.1 5.5 0.64 10.5 0.1 6.7 3 2 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF48247.1 - 3.1e-09 36.2 9.5 0.26 11.5 0.0 8.2 10 0 0 10 10 10 3 Leucine Rich repeat F-box-like PF12937.7 OWF48247.1 - 7.1e-07 29.0 2.0 2.5e-06 27.3 1.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 OWF48247.1 - 4.7e-06 26.3 2.4 1 9.2 0.0 5.0 5 1 0 5 5 5 2 Leucine rich repeat LRR_5 PF13306.6 OWF48247.1 - 8.3e-06 25.8 1.5 0.11 12.5 0.0 3.1 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) F-box PF00646.33 OWF48247.1 - 1.1e-05 25.1 1.7 7.5e-05 22.5 1.4 2.5 2 0 0 2 2 2 1 F-box domain RRM_7 PF16367.5 OWF48247.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif PCAF_N PF06466.11 OWF48247.1 - 0.73 9.4 3.9 0.25 10.9 0.7 1.8 2 0 0 2 2 2 0 PCAF (P300/CBP-associated factor) N-terminal domain RNA_helicase PF00910.22 OWF48250.1 - 0.0064 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 OWF48250.1 - 0.0079 16.1 0.1 0.018 15.0 0.1 1.6 1 1 0 1 1 1 1 NACHT domain T2SSE PF00437.20 OWF48250.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OWF48250.1 - 0.026 14.4 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 OWF48250.1 - 0.026 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF48250.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 OWF48250.1 - 0.049 13.6 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 OWF48250.1 - 0.053 12.7 0.2 0.93 8.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 OWF48250.1 - 0.066 12.4 0.5 0.14 11.4 0.2 1.7 1 1 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.12 OWF48250.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OWF48250.1 - 0.16 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF48250.1 - 0.2 12.0 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain fn3 PF00041.21 OWF48251.1 - 2.7e-08 34.0 2.9 6.7e-07 29.6 1.5 3.0 2 1 0 2 2 2 1 Fibronectin type III domain Sugar_tr PF00083.24 OWF48252.1 - 1.2e-19 70.5 8.9 1e-11 44.4 0.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF48252.1 - 1.1e-06 27.9 17.4 4.7e-06 25.8 5.6 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Ribonuclease PF00545.20 OWF48252.1 - 0.15 12.8 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 ribonuclease CvfB_WH PF17783.1 OWF48253.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 CvfB-like winged helix domain Tyrosinase PF00264.20 OWF48254.1 - 1.7e-32 113.5 0.9 8e-17 62.3 0.0 4.4 2 2 1 3 3 3 2 Common central domain of tyrosinase GREB1 PF15782.5 OWF48254.1 - 0.13 9.4 17.2 0.19 8.9 17.2 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 OWF48254.1 - 1.6 7.9 28.4 2.8 7.1 28.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein MecA PF05389.12 OWF48254.1 - 2.2 7.9 7.4 4 7.0 7.4 1.5 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Peptidase_M1 PF01433.20 OWF48254.1 - 5.5 6.5 7.2 0.28 10.7 0.1 2.1 2 0 0 2 2 2 0 Peptidase family M1 domain Ten_N PF06484.12 OWF48254.1 - 8 6.2 19.7 13 5.5 19.7 1.4 1 0 0 1 1 1 0 Teneurin Intracellular Region Cystatin PF00031.21 OWF48255.1 - 4.8e-12 46.0 0.2 5.6e-12 45.8 0.2 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 OWF48255.1 - 0.0027 18.0 0.1 0.0038 17.5 0.1 1.4 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor HET-s_218-289 PF11558.8 OWF48255.1 - 0.032 14.3 0.1 0.33 11.0 0.1 2.1 1 1 0 1 1 1 0 Het-s 218-289 ETRAMP PF09716.10 OWF48255.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_21 PF05050.12 OWF48256.1 - 0.00089 19.3 0.2 0.0016 18.5 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain RrnaAD PF00398.20 OWF48256.1 - 0.038 13.0 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 7tm_1 PF00001.21 OWF48257.1 - 3e-11 43.2 8.3 4.3e-11 42.6 8.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SPC25 PF06703.11 OWF48257.1 - 0.43 10.4 3.3 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4573 PF15140.6 OWF48258.1 - 0.006 16.4 35.5 0.01 15.6 9.4 2.7 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) DUF4845 PF16137.5 OWF48258.1 - 0.59 11.0 13.9 1.4e+02 3.4 0.1 6.3 1 1 6 7 7 7 0 Domain of unknown function (DUF4845) LRRC37 PF15779.5 OWF48258.1 - 4.4 7.7 12.8 4.8e+02 1.2 0.3 5.6 1 1 1 2 2 2 0 Leucine-rich repeat-containing protein 37 family PEP-utilizers PF00391.23 OWF48258.1 - 6.6 6.5 31.2 65 3.4 0.6 11.2 1 1 3 4 4 4 0 PEP-utilising enzyme, mobile domain Cystatin PF00031.21 OWF48259.1 - 9.2e-05 22.6 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain EVC2_like PF12297.8 OWF48260.1 - 0.0058 15.4 0.1 0.0071 15.1 0.1 1.0 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein Ank_2 PF12796.7 OWF48261.1 - 4.6e-21 75.2 2.1 3.8e-08 33.8 0.0 7.1 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48261.1 - 1.7e-19 69.9 2.0 0.19 12.3 0.0 9.8 8 1 2 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF48261.1 - 1.9e-13 50.2 4.6 0.066 13.7 0.2 9.3 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 OWF48261.1 - 2.2e-13 50.1 0.2 0.066 13.6 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF48261.1 - 2.1e-10 39.9 6.0 1.2 10.0 0.1 9.9 12 0 0 12 12 12 2 Ankyrin repeat SOCS_box PF07525.16 OWF48261.1 - 7.1e-09 35.9 0.4 7.1e-09 35.9 0.4 2.0 2 0 0 2 2 2 1 SOCS box TAF6_C PF07571.13 OWF48261.1 - 0.15 12.4 0.0 4 7.8 0.0 2.6 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Vsr PF03852.15 OWF48262.1 - 0.087 12.7 0.4 21 5.1 0.0 2.9 1 1 2 3 3 3 0 DNA mismatch endonuclease Vsr PLDc PF00614.22 OWF48262.1 - 0.092 13.0 6.0 69 3.9 0.2 5.6 6 1 0 6 6 6 0 Phospholipase D Active site motif HOK_GEF PF01848.16 OWF48262.1 - 1.1 8.8 16.3 9.2 5.8 0.1 5.7 2 2 5 7 7 7 0 Hok/gef family Toxin_19 PF08088.12 OWF48262.1 - 3.7 7.8 25.2 4 7.6 0.8 5.0 1 1 5 6 6 6 0 Conotoxin I-superfamily Vsr PF03852.15 OWF48263.1 - 0.065 13.1 3.4 36 4.3 0.0 3.7 3 1 1 4 4 4 0 DNA mismatch endonuclease Vsr Toxin_19 PF08088.12 OWF48264.1 - 0.15 12.2 26.1 6.6 6.9 2.8 5.9 1 1 5 6 6 6 0 Conotoxin I-superfamily CUB PF00431.20 OWF48265.1 - 4.1e-37 126.9 0.5 1.4e-22 80.1 1.4 2.5 2 0 0 2 2 2 2 CUB domain TMEM154 PF15102.6 OWF48265.1 - 0.0019 18.1 0.4 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family DAG1 PF05454.11 OWF48265.1 - 0.0019 17.6 0.2 0.0019 17.6 0.2 2.0 1 1 1 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM132D_C PF15706.5 OWF48265.1 - 0.039 13.7 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Collectrin PF16959.5 OWF48265.1 - 0.064 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Renal amino acid transporter CoA_binding_3 PF13727.6 OWF48265.1 - 0.2 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain Ldl_recept_a PF00057.18 OWF48265.1 - 0.27 11.5 18.1 1.4 9.2 18.1 2.2 1 1 0 1 1 1 0 Low-density lipoprotein receptor domain class A PMG PF05287.12 OWF48266.1 - 1.7e-08 34.7 0.0 3.5 7.6 0.0 4.9 1 1 4 5 5 5 4 PMG protein Keratin_B2 PF01500.17 OWF48266.1 - 0.19 11.7 0.0 7.9 6.4 0.0 3.4 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Coprogen_oxidas PF01218.18 OWF48267.1 - 9.1e-143 474.4 0.0 1.1e-142 474.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase LLGL PF08366.13 OWF48268.1 - 4.6e-36 123.3 0.0 1.2e-35 122.0 0.0 1.7 1 0 0 1 1 1 1 LLGL2 Lgl_C PF08596.10 OWF48268.1 - 6.8e-09 34.9 0.0 1.8e-06 26.9 0.0 3.0 3 0 0 3 3 3 2 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 OWF48268.1 - 2.8e-06 27.5 0.1 0.96 9.8 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 OWF48268.1 - 9.5e-06 25.3 0.1 2.5e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin WD40 PF00400.32 OWF48268.1 - 0.00049 20.9 2.1 8.3 7.5 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Skp1 PF01466.19 OWF48269.1 - 1.3 9.2 3.5 3.1 8.0 3.1 1.9 2 0 0 2 2 2 0 Skp1 family, dimerisation domain STI1 PF17830.1 OWF48270.1 - 0.04 13.8 0.0 1.4 8.9 0.2 2.7 2 0 0 2 2 2 0 STI1 domain UBM PF14377.6 OWF48270.1 - 0.067 12.7 0.7 0.36 10.4 0.7 2.4 1 0 0 1 1 1 0 Ubiquitin binding region DUF1272 PF06906.11 OWF48270.1 - 0.18 11.9 1.6 0.61 10.2 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rhodanese PF00581.20 OWF48271.1 - 2.7e-11 44.0 0.0 4.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain SAP PF02037.27 OWF48271.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 SAP domain p450 PF00067.22 OWF48275.1 - 8.1e-42 143.5 0.0 1.4e-41 142.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SopD PF11047.8 OWF48275.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Salmonella outer protein D TIR_2 PF13676.6 OWF48276.1 - 4.2e-19 69.3 0.4 5.3e-14 52.8 0.0 3.4 2 1 0 2 2 2 2 TIR domain DUF4062 PF13271.6 OWF48276.1 - 0.12 12.8 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) 7tm_1 PF00001.21 OWF48279.1 - 3.9e-48 164.1 14.9 6.3e-48 163.4 14.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF48279.1 - 8e-12 45.1 16.1 1.2e-11 44.5 16.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF48279.1 - 1.1e-06 28.6 11.2 1.1e-06 28.6 11.2 2.7 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF202 PF02656.15 OWF48281.1 - 0.01 16.3 0.1 0.014 15.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) CYYR1 PF10873.8 OWF48281.1 - 7.3 7.0 27.0 24 5.3 27.0 2.1 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF948 PF06103.11 OWF48282.1 - 0.0045 17.2 6.6 0.21 11.9 2.3 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Cas9_a PF18470.1 OWF48282.1 - 0.019 14.5 9.0 2.4 7.6 0.5 3.1 1 1 2 3 3 3 0 Cas9 alpha-helical lobe domain MCPsignal PF00015.21 OWF48282.1 - 0.027 14.3 2.3 0.079 12.8 2.4 1.7 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec20 PF03908.13 OWF48282.1 - 0.066 13.1 11.3 0.69 9.9 2.3 3.0 1 1 1 2 2 2 0 Sec20 Laminin_II PF06009.12 OWF48282.1 - 0.13 12.3 0.3 0.18 11.8 0.3 1.2 1 0 0 1 1 1 0 Laminin Domain II MetOD2 PF18548.1 OWF48282.1 - 0.2 11.8 7.7 7.9 6.7 0.9 3.3 1 1 3 4 4 4 0 Metanogen output domain 2 CCDC154 PF15450.6 OWF48282.1 - 1.2 7.6 7.9 1.5 7.3 7.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Noelin-1 PF12308.8 OWF48282.1 - 3.9 7.5 14.5 8.6 6.4 4.3 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein YabA PF06156.13 OWF48282.1 - 4.2 8.1 12.8 25 5.6 12.8 2.2 1 1 0 1 1 1 0 Initiation control protein YabA LXG PF04740.12 OWF48282.1 - 4.8 6.8 16.3 8.1 6.1 5.1 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF745 PF05335.13 OWF48282.1 - 7.3 6.3 9.2 12 5.6 8.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Synaptonemal_3 PF15191.6 OWF48282.1 - 7.6 6.4 11.0 8.7 6.2 2.4 2.6 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 Homeodomain PF00046.29 OWF48283.1 - 9.5e-22 76.6 2.3 1.7e-21 75.8 2.3 1.4 1 0 0 1 1 1 1 Homeodomain Methyltransf_FA PF12248.8 OWF48285.1 - 1.3e-28 99.3 0.1 1.9e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase Lectin_C PF00059.21 OWF48285.1 - 3e-08 34.3 4.6 4.8e-07 30.5 1.0 2.4 2 0 0 2 2 2 2 Lectin C-type domain ENTH PF01417.20 OWF48286.1 - 2.2e-43 147.2 0.1 3.8e-43 146.5 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OWF48286.1 - 3.3e-05 23.0 0.0 5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF3240 PF11582.8 OWF48287.1 - 0.00029 20.9 7.5 2.9 8.1 0.1 4.0 1 1 4 5 5 5 4 Protein of unknown function (DUF3240) HHH PF00633.23 OWF48287.1 - 0.0041 16.9 5.7 51 4.0 0.0 7.7 7 2 4 11 11 11 0 Helix-hairpin-helix motif SCP1201-deam PF14428.6 OWF48287.1 - 0.061 13.2 14.3 0.18 11.7 2.3 3.2 1 1 2 3 3 3 0 SCP1.201-like deaminase DUF2345 PF10106.9 OWF48287.1 - 0.21 11.5 2.1 1.9 8.4 0.5 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) SAM_PNT PF02198.16 OWF48287.1 - 0.21 11.6 0.0 44 4.1 0.0 3.2 1 1 3 4 4 4 0 Sterile alpha motif (SAM)/Pointed domain AcetylCoA_hydro PF02550.15 OWF48287.1 - 0.23 11.4 1.8 1.5 8.7 0.3 2.2 1 1 1 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain FdsD PF11390.8 OWF48287.1 - 0.36 11.2 5.4 12 6.3 0.7 3.4 1 1 3 4 4 4 0 NADH-dependant formate dehydrogenase delta subunit FdsD DUF4637 PF15470.6 OWF48287.1 - 0.62 9.8 6.9 22 4.8 0.7 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) DUF1104 PF06518.11 OWF48287.1 - 0.73 10.3 2.9 12 6.4 1.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) PLD_C PF12357.8 OWF48287.1 - 0.91 9.5 7.8 25 4.9 0.3 3.4 1 1 1 3 3 3 0 Phospholipase D C terminal 7tm_1 PF00001.21 OWF48288.1 - 5.4e-56 189.8 21.7 7.3e-56 189.4 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF48288.1 - 1.3e-11 44.4 23.3 1.9e-11 43.9 23.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF48288.1 - 3.5e-06 26.5 23.5 3.5e-06 26.5 23.5 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF1467 PF07330.12 OWF48288.1 - 0.034 14.1 2.9 0.068 13.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) 7tm_4 PF13853.6 OWF48288.1 - 0.33 10.6 16.2 0.56 9.9 16.2 1.4 1 0 0 1 1 1 0 Olfactory receptor Voltage_CLC PF00654.20 OWF48288.1 - 0.61 9.3 9.7 0.074 12.3 5.6 1.5 2 0 0 2 2 2 0 Voltage gated chloride channel Ig_3 PF13927.6 OWF48289.1 - 6e-37 126.1 28.6 9.7e-07 29.3 0.2 7.0 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 OWF48289.1 - 6.1e-25 87.1 13.1 5.3e-06 26.4 0.0 7.3 7 3 0 7 7 7 4 Immunoglobulin I-set domain C2-set_2 PF08205.12 OWF48289.1 - 3.8e-22 78.2 7.6 4.5e-14 52.3 0.2 4.7 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF48289.1 - 7.9e-19 67.8 13.6 9.3e-06 25.8 0.1 7.2 5 2 2 7 7 7 3 Immunoglobulin V-set domain ig PF00047.25 OWF48289.1 - 8.7e-18 64.3 18.7 0.00034 20.7 0.2 7.5 6 1 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 OWF48289.1 - 5.4e-15 55.5 17.8 5.6e-05 23.4 0.6 6.5 6 1 0 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 OWF48289.1 - 1.2e-07 31.9 4.9 4.6e-07 30.1 0.3 3.7 4 0 0 4 4 4 1 Fibronectin type III domain Ig_4 PF16680.5 OWF48289.1 - 1.3e-07 31.8 0.0 0.00043 20.5 0.0 5.1 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 OWF48289.1 - 1.1e-05 25.9 0.2 1.1e-05 25.9 0.2 4.4 5 0 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain Ig_5 PF16681.5 OWF48289.1 - 1.8e-05 25.1 0.9 0.17 12.3 0.0 4.7 4 1 0 4 4 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF48289.1 - 0.0021 17.6 0.2 0.36 10.4 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.15 OWF48289.1 - 0.0039 17.6 12.9 0.046 14.1 0.1 6.0 6 1 0 6 6 6 1 Immunoglobulin C1-set domain DUF5438 PF17506.2 OWF48289.1 - 0.032 14.6 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5438) Asp-Al_Ex PF06826.12 OWF48289.1 - 0.049 13.5 0.1 3.8 7.3 0.1 2.3 2 0 0 2 2 2 0 Predicted Permease Membrane Region Galactosyl_T PF01762.21 OWF48290.1 - 2e-42 145.2 0.1 3.5e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF48290.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 OWF48291.1 - 4.2e-41 140.9 0.0 6.1e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF48291.1 - 4e-05 23.2 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Nab2p_Zf1 PF18260.1 OWF48292.1 - 0.028 14.3 10.2 55 3.8 0.0 5.4 5 0 0 5 5 5 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Spermine_synth PF01564.17 OWF48293.1 - 2.7e-21 75.9 1.3 7.8e-21 74.3 0.7 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OWF48293.1 - 6.2e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain SpmSyn_N PF17950.1 OWF48293.1 - 1.2e-05 25.4 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase N -terminal Methyltransf_25 PF13649.6 OWF48293.1 - 0.0022 18.7 0.0 0.0047 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 OWF48293.1 - 0.011 15.0 0.1 0.021 14.1 0.1 1.5 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain IBR PF01485.21 OWF48294.1 - 1.2e-06 28.7 41.8 1.3e-05 25.3 11.0 3.6 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain Ribosomal_L37ae PF01780.19 OWF48294.1 - 0.017 15.2 1.7 0.061 13.4 1.7 1.9 1 0 0 1 1 1 0 Ribosomal L37ae protein family IBR PF01485.21 OWF48295.1 - 0.0058 16.8 15.4 0.0058 16.8 15.4 3.8 1 1 1 3 3 3 2 IBR domain, a half RING-finger domain Peptidase_M1 PF01433.20 OWF48296.1 - 6.5e-74 248.2 2.1 1.3e-73 247.2 2.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OWF48296.1 - 5.8e-69 233.0 1.2 8.7e-69 232.5 1.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OWF48296.1 - 3.9e-45 154.3 0.0 6.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2436 PF10365.9 OWF48296.1 - 0.096 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Death PF00531.22 OWF48298.1 - 0.0096 16.1 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 1 Death domain DUF446 PF04287.12 OWF48298.1 - 0.037 14.1 0.2 72 3.5 0.0 4.6 4 1 1 5 5 5 0 tRNA pseudouridine synthase C GDYXXLXY PF14345.6 OWF48298.1 - 1.5 8.6 7.2 15 5.4 1.2 3.4 1 1 0 2 2 2 0 GDYXXLXY protein DUF2291 PF10054.9 OWF48301.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) Death PF00531.22 OWF48302.1 - 0.16 12.1 0.1 0.56 10.4 0.1 1.9 1 0 0 1 1 1 0 Death domain rve PF00665.26 OWF48303.1 - 0.002 18.3 0.0 0.0049 17.1 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 OWF48303.1 - 0.007 16.5 0.2 0.007 16.5 0.2 2.7 3 0 0 3 3 3 1 HTH-like domain Zip PF02535.22 OWF48304.1 - 0.15 11.3 1.4 0.16 11.1 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.12 OWF48304.1 - 0.44 9.9 8.8 0.63 9.4 8.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 OWF48304.1 - 0.64 8.2 7.8 0.68 8.2 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OWF48304.1 - 0.64 8.7 3.7 0.79 8.4 3.7 1.1 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 OWF48304.1 - 1.1 9.1 9.9 1.8 8.3 9.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Transketolase_N PF00456.21 OWF48305.1 - 3.9e-51 174.0 0.0 6.8e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OWF48305.1 - 4.3e-37 127.5 0.0 7.7e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OWF48305.1 - 2.5e-25 88.7 0.0 6.7e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 OWF48305.1 - 5.3e-09 35.4 0.0 8.4e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OWF48305.1 - 2.9e-07 30.0 0.0 1.1e-05 24.7 0.0 2.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 OWF48305.1 - 6.9e-07 28.4 0.1 1.6e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 XFP N-terminal domain TPP_enzyme_C PF02775.21 OWF48305.1 - 4.8e-06 26.4 0.2 9.2e-05 22.3 0.1 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain VGLL4 PF15245.6 OWF48306.1 - 8.6e-13 48.9 9.8 1.1e-10 41.9 9.6 3.0 2 1 0 2 2 2 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.14 OWF48306.1 - 1.4e-06 27.9 0.0 1.5 8.6 0.0 3.6 3 0 0 3 3 3 3 Vestigial/Tondu family DUF5582 PF17819.1 OWF48306.1 - 0.1 13.0 1.5 0.12 12.8 0.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5582) Rft-1 PF04506.13 OWF48307.1 - 1.4e-126 423.2 17.5 1.7e-126 423.0 17.5 1.0 1 0 0 1 1 1 1 Rft protein MAGE PF01454.19 OWF48308.1 - 1.7e-33 116.1 0.1 5.7e-32 111.2 0.1 2.3 1 1 0 1 1 1 1 MAGE family TatC PF00902.18 OWF48309.1 - 0.057 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF1515 PF07439.11 OWF48309.1 - 0.13 12.2 7.0 0.93 9.5 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) UPF0227 PF05728.12 OWF48309.1 - 0.16 11.9 6.5 0.095 12.6 2.2 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF2232 PF09991.9 OWF48309.1 - 0.46 9.6 2.0 0.62 9.2 0.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF2779 PF11074.8 OWF48309.1 - 1.2 9.6 4.5 1.1 9.7 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) Shisa PF13908.6 OWF48310.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 OWF48310.1 - 2.2 7.6 10.5 16 4.8 10.5 2.2 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TPT PF03151.16 OWF48311.1 - 1.3e-08 34.5 3.2 1.6e-08 34.3 3.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OWF48311.1 - 1.6e-05 25.1 10.3 6.4e-05 23.1 3.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF2085 PF09858.9 OWF48311.1 - 4.7 7.8 14.3 2.8 8.5 1.3 3.4 1 1 2 3 3 3 0 Predicted membrane protein (DUF2085) Acyltransferase PF01553.21 OWF48313.1 - 7.7e-25 87.1 0.0 1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DPM3 PF08285.11 OWF48315.1 - 6.4e-28 96.8 0.4 8.8e-28 96.3 0.4 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) B12D PF06522.11 OWF48315.1 - 0.062 13.1 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3678 PF12435.8 OWF48315.1 - 0.11 11.9 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF3742 PF12553.8 OWF48315.1 - 0.5 10.5 1.6 6.5 6.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Tim17 PF02466.19 OWF48316.1 - 8e-26 90.6 5.0 1.1e-25 90.1 5.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TRAM_LAG1_CLN8 PF03798.16 OWF48317.1 - 7.2e-14 52.0 23.8 7.2e-14 52.0 23.8 1.7 1 1 1 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 OWF48318.1 - 1.4e-10 41.3 20.8 2.3e-10 40.5 20.8 1.3 1 0 0 1 1 1 1 TLC domain DUF2627 PF11118.8 OWF48318.1 - 0.19 12.3 1.5 0.61 10.7 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) DnaJ PF00226.31 OWF48320.1 - 1.7e-27 95.3 1.8 1.7e-27 95.3 1.8 2.4 2 1 0 2 2 2 1 DnaJ domain LON_substr_bdg PF02190.16 OWF48321.1 - 6.8e-21 75.1 0.0 1.2e-20 74.3 0.0 1.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 OWF48321.1 - 1.8e-10 40.9 0.0 4.6e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CC2-LZ PF16516.5 OWF48322.1 - 1.1e-21 77.0 11.2 1.1e-21 77.0 11.2 7.3 3 2 4 7 7 7 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf_C2H2_10 PF18414.1 OWF48322.1 - 3.5e-10 39.2 10.2 6.9e-10 38.3 10.2 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger NEMO PF11577.8 OWF48322.1 - 5.6e-06 26.3 12.4 5.6e-06 26.3 12.4 6.5 6 1 1 7 7 7 2 NF-kappa-B essential modulator NEMO bZIP_2 PF07716.15 OWF48322.1 - 0.0001 22.3 5.7 0.0001 22.3 5.7 10.6 11 1 1 12 12 12 1 Basic region leucine zipper Phasin_2 PF09361.10 OWF48322.1 - 0.00013 22.2 0.7 0.00013 22.2 0.7 3.2 4 0 0 4 4 4 1 Phasin protein HOOK PF05622.12 OWF48322.1 - 0.00037 18.8 37.1 0.00037 18.8 37.1 4.1 1 1 3 4 4 4 2 HOOK protein bZIP_1 PF00170.21 OWF48322.1 - 0.0013 18.7 3.6 0.0013 18.7 3.6 11.2 7 4 4 11 11 11 2 bZIP transcription factor PSD2 PF07624.11 OWF48322.1 - 5.2 6.9 6.3 29 4.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) Hist_deacetyl PF00850.19 OWF48323.1 - 2.5e-170 565.8 1.7 2.8e-89 299.6 0.1 2.4 2 0 0 2 2 2 2 Histone deacetylase domain zf-UBP PF02148.19 OWF48323.1 - 3.9e-17 62.3 9.5 1.3e-16 60.6 9.5 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_7 PF02591.15 OWF48323.1 - 0.078 13.2 0.0 25 5.2 0.0 3.0 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-UBP_var PF17807.1 OWF48323.1 - 0.081 12.7 0.4 0.36 10.6 0.4 2.1 1 0 0 1 1 1 0 Variant UBP zinc finger YgaB PF14182.6 OWF48323.1 - 1.1 9.7 10.1 0.73 10.3 0.5 3.7 4 0 0 4 4 4 0 YgaB-like protein Cu-oxidase_3 PF07732.15 OWF48324.1 - 1.3e-34 118.8 1.7 1.3e-32 112.3 0.4 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF48324.1 - 3.6e-30 105.2 0.4 2e-29 102.8 0.3 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF48324.1 - 5.6e-29 100.6 3.6 2.2e-25 89.0 0.0 4.3 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OWF48325.1 - 7.8e-43 145.3 0.9 3.4e-38 130.3 0.2 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF48325.1 - 4.4e-33 113.9 3.5 2.2e-28 98.7 0.1 4.0 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF48325.1 - 6.5e-30 104.3 0.1 1.3e-27 96.9 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase DUF3589 PF12141.8 OWF48325.1 - 0.17 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Beta-mannosyltransferases DUF2615 PF11027.8 OWF48326.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) PalH PF08733.10 OWF48326.1 - 0.09 11.8 0.0 0.097 11.7 0.0 1.0 1 0 0 1 1 1 0 PalH/RIM21 Orf78 PF06024.12 OWF48326.1 - 0.11 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Glycophorin_A PF01102.18 OWF48326.1 - 0.23 11.7 0.8 0.43 10.8 0.3 1.6 1 1 0 1 1 1 0 Glycophorin A Cu-oxidase_3 PF07732.15 OWF48327.1 - 6.6e-41 139.1 0.4 5.6e-38 129.6 0.2 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF48327.1 - 7.1e-29 101.0 0.4 7.3e-27 94.4 0.1 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF48327.1 - 1.6e-23 82.9 0.3 2.4e-17 62.9 0.0 4.1 3 1 0 3 3 3 3 Multicopper oxidase DUF3589 PF12141.8 OWF48327.1 - 0.17 10.4 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Beta-mannosyltransferases Cu-oxidase_3 PF07732.15 OWF48328.1 - 2.3e-42 143.8 0.7 2.4e-38 130.8 0.3 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF48328.1 - 5.4e-33 113.6 3.5 5.1e-28 97.5 0.1 4.1 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF48328.1 - 2e-29 102.8 0.0 4.3e-27 95.2 0.1 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OWF48329.1 - 1.4e-40 138.0 2.4 1.4e-37 128.4 0.9 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF48329.1 - 9.7e-36 122.5 4.1 1.8e-31 108.7 0.3 3.7 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF48329.1 - 8.9e-32 110.4 0.2 3.6e-28 98.7 0.1 2.7 3 0 0 3 3 3 2 Multicopper oxidase CGI-121 PF08617.10 OWF48330.1 - 1.6e-38 132.4 3.8 1.8e-38 132.2 3.8 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Adaptin_N PF01602.20 OWF48331.1 - 2.7e-126 422.2 11.7 3.4e-126 421.9 11.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OWF48331.1 - 7.9e-62 207.9 0.5 2.2e-61 206.4 0.5 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OWF48331.1 - 1.5e-39 134.7 0.0 3.4e-39 133.6 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OWF48331.1 - 1.3e-18 67.2 0.5 1.5e-07 31.7 0.0 5.9 3 2 4 7 7 7 3 HEAT repeats Cnd1 PF12717.7 OWF48331.1 - 3e-08 33.9 15.6 0.0043 17.1 0.5 4.4 3 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OWF48331.1 - 0.00039 20.4 3.5 23 5.6 0.0 5.8 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 OWF48331.1 - 0.002 18.6 1.5 0.25 11.9 0.2 4.3 5 0 0 5 5 5 1 HEAT-like repeat Phage_tail_U PF06141.11 OWF48331.1 - 0.1 13.0 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Phage minor tail protein U HEAT_PBS PF03130.16 OWF48331.1 - 0.2 12.4 0.2 12 6.9 0.1 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Il13Ra_Ig PF18001.1 OWF48332.1 - 0.026 14.6 2.2 0.48 10.5 0.1 2.2 1 1 1 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain DUF481 PF04338.12 OWF48332.1 - 0.19 11.7 0.6 0.34 10.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF481 OTU PF02338.19 OWF48333.1 - 0.058 13.9 0.0 0.14 12.7 0.0 1.6 1 1 0 1 1 1 0 OTU-like cysteine protease WH1 PF00568.23 OWF48336.1 - 8 6.4 53.8 19 5.2 0.8 11.7 3 3 7 12 12 12 0 WH1 domain Ig_3 PF13927.6 OWF48337.1 - 1.7e-85 281.7 0.5 3.1e-15 56.5 0.0 7.4 7 0 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 OWF48337.1 - 8e-81 266.2 0.0 9.3e-14 51.3 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin I-set domain Pkinase_Tyr PF07714.17 OWF48337.1 - 4.6e-68 229.3 0.0 6.8e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.6 OWF48337.1 - 3.1e-56 187.6 0.7 2.3e-10 40.7 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 OWF48337.1 - 3.6e-49 164.9 0.5 3.4e-10 40.0 0.0 7.4 7 0 0 7 7 7 7 Immunoglobulin domain Pkinase PF00069.25 OWF48337.1 - 6.6e-33 114.2 0.0 9.8e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 OWF48337.1 - 2e-25 89.1 15.2 0.0006 20.0 0.1 11.1 7 6 3 10 10 10 6 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF48337.1 - 1.1e-21 76.1 0.2 0.0025 17.4 0.0 7.4 7 0 0 7 7 7 4 Immunoglobulin domain Ig_4 PF16680.5 OWF48337.1 - 4.2e-12 46.1 0.1 1.2 9.5 0.0 6.8 7 0 0 7 7 6 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 OWF48337.1 - 6.2e-11 42.2 0.6 0.14 12.2 0.0 7.0 7 0 0 7 7 6 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF48337.1 - 1.7e-09 37.6 0.2 4.2 7.5 0.0 6.7 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 OWF48337.1 - 5.2e-06 26.8 0.9 0.17 12.2 0.0 5.8 6 0 0 6 6 5 1 Immunoglobulin C1-set domain Herpes_gE PF02480.16 OWF48337.1 - 3.1e-05 22.9 0.4 2.5 6.8 0.0 5.2 3 2 2 5 5 5 2 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 OWF48337.1 - 0.0021 18.0 0.1 1.8 8.7 0.0 4.1 4 1 0 4 4 4 1 C17orf99 Ig domain ACAS_N PF16177.5 OWF48337.1 - 0.029 14.3 0.1 0.16 11.9 0.0 2.3 3 0 0 3 3 2 0 Acetyl-coenzyme A synthetase N-terminus Pkinase_fungal PF17667.1 OWF48337.1 - 0.074 11.8 1.3 0.15 10.8 1.3 1.4 1 1 0 1 1 1 0 Fungal protein kinase InaF-motif PF15018.6 OWF48338.1 - 2e-18 66.0 3.6 2.6e-18 65.6 3.6 1.2 1 0 0 1 1 1 1 TRP-interacting helix Orf78 PF06024.12 OWF48338.1 - 0.049 13.9 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Costars PF14705.6 OWF48339.1 - 5.9e-30 103.3 0.2 8.9e-30 102.7 0.2 1.3 1 0 0 1 1 1 1 Costars DUF3060 PF11259.8 OWF48340.1 - 8.5e-15 54.2 99.8 0.0026 17.4 8.2 11.1 1 1 10 12 12 12 12 Protein of unknown function (DUF3060) DUF4440 PF14534.6 OWF48340.1 - 6.5e-07 29.7 10.7 9.6 6.7 0.1 7.8 1 1 6 8 8 8 2 Domain of unknown function (DUF4440) PCC_BT PF18140.1 OWF48340.1 - 0.00016 22.0 44.7 1 9.7 7.7 6.5 1 1 5 6 6 6 5 Propionyl-coenzyme A carboxylase BT domain DUF5590 PF17881.1 OWF48340.1 - 0.0064 16.6 0.8 4.8 7.4 0.1 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5590) DapH_N PF08503.10 OWF48340.1 - 0.02 15.1 15.2 2.6 8.3 0.7 6.8 2 2 5 7 7 7 0 Tetrahydrodipicolinate succinyltransferase N-terminal Oxidoreduct_C PF16490.5 OWF48340.1 - 0.036 13.7 19.2 1.8 8.2 0.5 5.7 1 1 5 6 6 6 0 Putative oxidoreductase C terminal domain VWD PF00094.25 OWF48340.1 - 0.42 10.9 48.4 1.4 9.1 10.4 4.7 1 1 2 3 3 3 0 von Willebrand factor type D domain DUF3868 PF12984.7 OWF48340.1 - 2.3 8.1 22.2 15 5.5 0.2 7.3 1 1 5 8 8 8 0 Domain of unknown function, B. Theta Gene description (DUF3868) Avidin PF01382.17 OWF48340.1 - 2.5 8.6 16.0 80 3.8 0.1 5.9 3 3 1 4 4 4 0 Avidin family Pkinase PF00069.25 OWF48341.1 - 7.8e-20 71.3 0.0 3.8e-19 69.1 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF48341.1 - 5e-14 52.2 0.0 1.9e-13 50.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PGM_PMM_I PF02878.16 OWF48341.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I EGF PF00008.27 OWF48342.1 - 2.4e-33 114.1 82.9 6.1e-09 36.0 6.9 6.2 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.7 OWF48342.1 - 1.5e-15 57.2 69.2 4.4e-05 24.0 6.2 7.0 6 0 0 6 6 6 5 Human growth factor-like EGF EGF_CA PF07645.15 OWF48342.1 - 2.5e-10 40.4 69.2 0.0024 18.0 8.6 5.9 2 1 3 5 5 5 5 Calcium-binding EGF domain EGF_2 PF07974.13 OWF48342.1 - 3.1e-08 33.9 90.1 0.0018 18.6 9.8 6.3 6 0 0 6 6 6 5 EGF-like domain EGF_3 PF12947.7 OWF48342.1 - 0.00039 20.5 57.6 0.13 12.5 4.3 6.6 3 3 3 6 6 6 4 EGF domain cEGF PF12662.7 OWF48342.1 - 0.0012 18.8 3.7 0.0012 18.8 3.7 5.7 5 1 0 5 5 5 2 Complement Clr-like EGF-like PTase_Orf2 PF11468.8 OWF48342.1 - 0.058 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 adh_short PF00106.25 OWF48343.1 - 2.1e-49 167.6 0.0 4e-49 166.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF48343.1 - 7e-33 114.1 0.0 9.3e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF48343.1 - 5.2e-10 39.5 0.1 8.2e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF963 PF06131.11 OWF48344.1 - 0.00014 21.2 5.8 0.0075 15.7 0.9 2.6 1 1 1 2 2 2 2 Schizosaccharomyces pombe repeat of unknown function (DUF963) NNMT_PNMT_TEMT PF01234.17 OWF48345.1 - 4.8e-32 111.1 0.0 5.5e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 OWF48345.1 - 1.9e-05 25.2 0.0 2.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF48345.1 - 3.8e-05 24.3 0.0 6.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF48345.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF48345.1 - 0.00095 19.8 0.0 0.0015 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF48345.1 - 0.0065 16.3 0.0 0.0071 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 OWF48345.1 - 0.079 12.0 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Ubie_methyltran PF01209.18 OWF48345.1 - 0.15 11.4 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ras PF00071.22 OWF48347.1 - 1.7e-56 190.3 0.1 1.9e-56 190.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF48347.1 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF48347.1 - 2.2e-09 37.0 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF48347.1 - 6.3e-06 26.2 0.1 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF48347.1 - 0.00049 20.1 0.1 0.00081 19.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF48347.1 - 0.0005 19.7 0.3 0.0023 17.5 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OWF48347.1 - 0.023 14.2 0.2 0.07 12.7 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B NHL PF01436.21 OWF48348.1 - 2.6e-05 24.0 3.5 0.098 12.7 0.0 3.7 3 0 0 3 3 3 2 NHL repeat Sulfotransfer_2 PF03567.14 OWF48350.1 - 6.4e-38 131.1 3.9 8.8e-36 124.1 0.8 2.2 1 1 0 2 2 2 2 Sulfotransferase family Chordopox_A13L PF05961.11 OWF48350.1 - 0.15 12.3 0.1 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Nop14 PF04147.12 OWF48352.1 - 1.4 7.0 39.0 2.2 6.4 39.0 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_54 PF04666.13 OWF48353.1 - 1.5e-77 260.3 3.2 4.1e-77 258.9 3.2 1.6 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF5374 PF17344.2 OWF48354.1 - 0.0001 22.1 28.3 0.94 9.4 0.0 9.5 5 3 5 12 12 12 4 Family of unknown function (DUF5374) DUF4968 PF16338.5 OWF48354.1 - 0.005 17.1 1.1 1.1 9.6 0.0 2.8 1 1 0 2 2 2 2 Domain of unknown function (DUF4968) Par3_HAL_N_term PF12053.8 OWF48354.1 - 1.6 9.0 9.7 9.6 6.5 0.4 4.3 2 2 3 5 5 5 0 N-terminal of Par3 and HAL proteins WHAMM-JMY_N PF15920.5 OWF48354.1 - 2.1 8.3 49.2 9.9 6.1 1.2 12.1 1 1 7 10 10 10 0 N-terminal of Junction-mediating and WASP homolog-associated Cupin_8 PF13621.6 OWF48355.1 - 1.9e-64 217.8 1.0 1.9e-64 217.8 1.0 1.5 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 OWF48355.1 - 3.7e-06 26.6 0.0 0.017 14.6 0.0 2.5 2 0 0 2 2 2 2 Cupin superfamily protein dCMP_cyt_deam_1 PF00383.23 OWF48356.1 - 2.2e-15 56.4 0.4 2.8e-15 56.0 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OWF48356.1 - 2e-11 44.2 0.2 5.1e-10 39.7 0.2 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OWF48356.1 - 0.053 13.1 0.5 0.36 10.4 0.1 2.0 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Fucokinase PF07959.12 OWF48356.1 - 0.078 11.9 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase EphA2_TM PF14575.6 OWF48357.1 - 0.033 15.1 0.0 0.069 14.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4079 PF13301.6 OWF48357.1 - 0.037 14.2 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) UPF0697 PF15117.6 OWF48357.1 - 0.11 12.6 0.3 0.83 9.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 Cadherin_C_2 PF16492.5 OWF48357.1 - 0.13 13.0 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Laminin_EGF PF00053.24 OWF48358.1 - 3.5e-05 23.9 139.6 0.00072 19.6 20.7 8.8 4 3 5 9 9 9 5 Laminin EGF domain FxsA PF04186.13 OWF48358.1 - 0.051 13.7 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein EphA2_TM PF14575.6 OWF48358.1 - 0.098 13.6 0.3 0.37 11.7 0.3 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 OWF48358.1 - 4.6 7.6 5.5 0.76 10.1 0.1 2.3 3 0 0 3 3 3 0 Protein melan-A zf-TRAF PF02176.18 OWF48359.1 - 5.1e-24 84.7 35.0 1.4e-16 60.9 5.6 4.8 3 1 2 5 5 5 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 OWF48359.1 - 2.7e-11 43.1 5.0 2.7e-11 43.1 5.0 3.6 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF48359.1 - 8.3e-10 38.7 5.3 8.3e-10 38.7 5.3 2.6 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF48359.1 - 1.8e-09 37.3 4.9 1.8e-09 37.3 4.9 3.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF48359.1 - 4.3e-09 36.6 5.1 4.3e-09 36.6 5.1 3.6 3 1 2 5 5 1 1 Ring finger domain zf-TRAF_2 PF15965.5 OWF48359.1 - 6.2e-08 33.0 24.4 0.0044 17.4 3.1 4.4 1 1 3 4 4 4 3 TRAF-like zinc-finger zf-RING_UBOX PF13445.6 OWF48359.1 - 2.8e-07 30.5 7.5 1e-06 28.7 7.5 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF48359.1 - 2.3e-06 27.3 2.4 2.3e-06 27.3 2.4 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF48359.1 - 9.9e-06 25.4 3.2 9.9e-06 25.4 3.2 3.5 2 1 1 3 3 1 1 zinc-RING finger domain U-box PF04564.15 OWF48359.1 - 3.8e-05 23.8 0.0 0.0025 18.0 0.0 3.0 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.7 OWF48359.1 - 0.00027 21.2 6.4 0.00027 21.2 6.4 4.2 3 2 1 4 4 3 1 RING-H2 zinc finger domain zf-Nse PF11789.8 OWF48359.1 - 0.00046 19.9 2.2 0.00046 19.9 2.2 3.5 2 1 1 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit XhlA PF10779.9 OWF48359.1 - 0.0006 20.0 2.5 0.0013 18.9 2.5 1.5 1 0 0 1 1 1 1 Haemolysin XhlA zf_C2HC_14 PF18574.1 OWF48359.1 - 0.0019 17.9 0.1 0.0019 17.9 0.1 3.1 3 0 0 3 3 3 1 C2HC Zing finger domain MAD PF05557.13 OWF48359.1 - 0.0021 16.5 0.6 0.0037 15.7 0.6 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein zf-ANAPC11 PF12861.7 OWF48359.1 - 0.0021 18.1 0.3 0.0021 18.1 0.3 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Nup54 PF13874.6 OWF48359.1 - 0.0051 16.9 1.7 0.03 14.4 0.1 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 KLRAQ PF10205.9 OWF48359.1 - 0.01 16.0 0.5 0.01 16.0 0.5 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Sina PF03145.16 OWF48359.1 - 0.013 15.5 3.5 0.013 15.5 3.5 3.4 1 1 2 3 3 3 0 Seven in absentia protein family DUF812 PF05667.11 OWF48359.1 - 0.018 14.0 6.3 0.027 13.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_1 PF00170.21 OWF48359.1 - 0.021 14.9 1.1 0.048 13.8 1.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor zf-RING_6 PF14835.6 OWF48359.1 - 0.025 14.5 0.9 0.077 12.9 0.9 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DivIC PF04977.15 OWF48359.1 - 0.071 12.9 1.6 0.16 11.8 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 OWF48359.1 - 0.26 9.8 7.8 0.39 9.2 7.8 1.2 1 0 0 1 1 1 0 Macoilin family SlyX PF04102.12 OWF48359.1 - 0.32 11.6 7.0 0.057 14.1 2.0 2.3 2 0 0 2 2 1 0 SlyX ADIP PF11559.8 OWF48359.1 - 0.35 11.0 6.6 0.25 11.4 4.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CREPT PF16566.5 OWF48359.1 - 0.72 10.0 4.8 0.22 11.7 0.9 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour A2L_zn_ribbon PF08792.10 OWF48359.1 - 8.6 6.2 7.7 17 5.3 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain 7TM_GPCR_Srw PF10324.9 OWF48360.1 - 4e-13 49.3 18.6 1.7e-07 30.8 4.8 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF48360.1 - 1.2e-11 44.4 16.5 1.6e-11 44.0 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DC_STAMP PF07782.13 OWF48361.1 - 9.4e-53 178.9 0.8 9.4e-53 178.9 0.8 1.7 2 0 0 2 2 2 1 DC-STAMP-like protein Prominin PF05478.11 OWF48361.1 - 0.00096 17.2 0.5 0.0016 16.5 0.5 1.3 1 0 0 1 1 1 1 Prominin Transcrip_act PF04949.13 OWF48361.1 - 0.0023 17.8 0.7 0.005 16.7 0.7 1.5 1 0 0 1 1 1 1 Transcriptional activator AAA_13 PF13166.6 OWF48361.1 - 0.0061 15.3 0.5 0.011 14.5 0.5 1.3 1 0 0 1 1 1 1 AAA domain Apolipoprotein PF01442.18 OWF48361.1 - 0.014 15.3 0.5 0.028 14.3 0.5 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 OWF48361.1 - 0.019 15.2 3.7 1.7 8.9 1.2 3.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Senescence PF06911.12 OWF48361.1 - 0.075 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Senescence-associated protein DUF4455 PF14643.6 OWF48361.1 - 0.17 10.5 1.4 0.26 9.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) zf-C2HC PF01530.18 OWF48361.1 - 0.22 11.8 3.3 0.53 10.5 3.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2HC type Baculo_PEP_C PF04513.12 OWF48361.1 - 0.32 11.0 2.7 0.4 10.7 0.6 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OWF48361.1 - 0.34 10.9 6.0 0.54 10.3 1.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 OWF48361.1 - 0.43 10.7 5.8 0.11 12.6 1.7 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.21 OWF48361.1 - 0.73 9.6 5.5 2.8 7.7 2.2 2.7 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-RING_2 PF13639.6 OWF48361.1 - 4.8 7.6 9.7 14 6.1 9.7 1.9 1 0 0 1 1 1 0 Ring finger domain DC_STAMP PF07782.13 OWF48362.1 - 2.7e-53 180.7 0.6 5.9e-53 179.5 0.6 1.6 1 0 0 1 1 1 1 DC-STAMP-like protein DUF948 PF06103.11 OWF48362.1 - 0.00058 20.1 2.8 0.74 10.1 1.2 3.5 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Transcrip_act PF04949.13 OWF48362.1 - 0.0019 18.1 0.8 0.0041 17.0 0.8 1.5 1 0 0 1 1 1 1 Transcriptional activator DUF1664 PF07889.12 OWF48362.1 - 0.0037 17.3 2.5 0.51 10.4 1.5 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) AAA_13 PF13166.6 OWF48362.1 - 0.0063 15.2 0.7 0.011 14.4 0.7 1.3 1 0 0 1 1 1 1 AAA domain Apolipoprotein PF01442.18 OWF48362.1 - 0.018 14.9 0.7 0.034 14.0 0.7 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PMEI PF04043.15 OWF48362.1 - 0.037 14.4 0.9 0.25 11.7 1.2 1.9 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Senescence PF06911.12 OWF48362.1 - 0.042 14.2 0.1 0.079 13.3 0.1 1.4 1 0 0 1 1 1 0 Senescence-associated protein Baculo_PEP_C PF04513.12 OWF48362.1 - 0.07 13.2 0.6 0.36 10.9 0.6 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAP206 PF12018.8 OWF48362.1 - 0.086 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function zf-C2HC PF01530.18 OWF48362.1 - 0.21 11.8 3.3 0.53 10.5 3.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2HC type ApoLp-III PF07464.11 OWF48362.1 - 0.42 10.7 5.2 0.16 12.1 1.9 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.21 OWF48362.1 - 0.49 10.2 6.2 0.85 9.4 1.4 2.9 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synuclein PF01387.17 OWF48362.1 - 0.74 10.0 3.6 0.87 9.8 0.7 2.2 1 1 1 2 2 2 0 Synuclein zf-C3HC4_3 PF13920.6 OWF48362.1 - 4.1 7.4 11.9 14 5.7 11.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Med25_VWA PF11265.8 OWF48365.1 - 5.6e-84 281.2 0.0 1.1e-83 280.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Med25 PF11232.8 OWF48365.1 - 1.2e-53 181.1 0.0 1.2e-53 181.1 0.0 2.7 2 0 0 2 2 2 1 Mediator complex subunit 25 PTOV activation and synapsin 2 TFIIA PF03153.13 OWF48365.1 - 0.007 16.4 58.4 0.007 16.4 58.4 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4948 PF16306.5 OWF48365.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) Piezo_RRas_bdg PF12166.8 OWF48365.1 - 5.3 6.2 15.6 9.2 5.4 15.6 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain GBP_PSP PF02425.15 OWF48366.1 - 0.0034 17.0 17.0 5.6 6.7 0.2 6.0 5 0 0 5 5 5 3 Paralytic/GBP/PSP peptide Mfa1 PF17445.2 OWF48366.1 - 0.0041 17.1 12.0 13 5.9 0.1 6.7 3 3 4 7 7 7 2 Mating factor A1 HIRA_B PF09453.10 OWF48366.1 - 0.21 11.5 2.0 41 4.2 0.2 3.8 3 0 0 3 3 3 0 HIRA B motif Gag_p12 PF01141.18 OWF48366.1 - 0.27 11.6 1.4 8.1 6.9 0.1 3.2 3 2 0 3 3 3 0 Gag polyprotein, inner coat protein p12 YadA_anchor PF03895.15 OWF48366.1 - 0.87 9.8 5.8 4.1 7.6 0.1 3.3 3 2 0 3 3 3 0 YadA-like membrane anchor domain Glyco_hydro_72 PF03198.14 OWF48366.1 - 0.89 8.7 2.6 53 2.9 0.1 4.1 1 1 3 5 5 5 0 Glucanosyltransferase FYRN PF05964.14 OWF48366.1 - 4.3 7.3 6.2 78 3.2 0.0 5.0 6 0 0 6 6 6 0 F/Y-rich N-terminus THDPS_N PF14790.6 OWF48367.1 - 0.002 18.0 9.3 76 3.1 0.0 9.7 10 3 1 11 11 11 2 Tetrahydrodipicolinate N-succinyltransferase N-terminal zf-H2C2_5 PF13909.6 OWF48368.1 - 0.00044 19.9 0.3 0.0013 18.4 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OWF48368.1 - 0.0063 17.3 2.8 2 9.5 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 OWF48368.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 OWF48368.1 - 0.11 13.0 3.1 0.14 12.7 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF48368.1 - 0.37 11.3 4.2 0.82 10.2 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Lectin_C PF00059.21 OWF48369.1 - 6.1e-18 65.5 1.7 9e-18 65.0 1.7 1.3 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF48369.1 - 0.003 17.5 0.2 0.003 17.5 0.2 2.3 2 0 0 2 2 2 1 PAN domain CDP-OH_P_transf PF01066.21 OWF48370.1 - 6.6e-16 58.8 0.1 6.6e-16 58.8 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NAD_binding_4 PF07993.12 OWF48371.1 - 3e-76 256.0 0.0 3.9e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 OWF48371.1 - 7.6e-30 103.0 0.6 2.2e-29 101.5 0.6 1.8 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OWF48371.1 - 9e-08 31.9 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OWF48371.1 - 2.2e-06 26.9 0.8 5.8e-05 22.2 0.6 2.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OWF48371.1 - 4.3e-06 26.1 0.0 7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OWF48371.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OWF48371.1 - 0.0029 18.0 0.0 0.0076 16.7 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 OWF48372.1 - 1e-77 260.8 0.0 1.3e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 OWF48372.1 - 1.5e-28 98.8 1.1 4.4e-28 97.3 0.3 2.2 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 OWF48372.1 - 5.6e-07 29.3 0.1 1.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OWF48372.1 - 1.6e-06 27.5 0.1 2.5e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OWF48372.1 - 2.2e-05 24.0 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OWF48372.1 - 0.00013 21.1 0.0 0.0026 16.8 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OWF48372.1 - 0.00028 21.3 0.0 0.00071 20.0 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OWF48372.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Mab-21 PF03281.14 OWF48373.1 - 1.1e-06 28.2 0.0 3e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.14 OWF48374.1 - 1.1e-06 28.2 0.0 3e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.14 OWF48377.1 - 6.8e-07 28.9 0.0 4.2e-06 26.3 0.0 2.3 1 1 1 2 2 2 1 Mab-21 protein Mab-21 PF03281.14 OWF48378.1 - 3.9e-06 26.4 0.0 9.3e-06 25.1 0.0 1.7 1 1 1 2 2 2 1 Mab-21 protein Neur_chan_LBD PF02931.23 OWF48380.1 - 2.6e-38 131.6 0.0 3.7e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48380.1 - 5.3e-25 88.9 0.0 7.1e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF5336 PF17270.2 OWF48380.1 - 0.42 10.2 1.4 0.86 9.2 0.8 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5336) Neur_chan_LBD PF02931.23 OWF48381.1 - 3.2e-39 134.6 0.1 5.2e-39 133.9 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48381.1 - 8.4e-24 84.9 4.0 1.3e-22 81.0 4.0 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Plant_tran PF04827.14 OWF48381.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein DUF4131 PF13567.6 OWF48381.1 - 0.25 11.0 0.9 6.2 6.4 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Neur_chan_LBD PF02931.23 OWF48382.1 - 2.2e-08 33.8 0.0 2.4e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain EST1_DNA_bind PF10373.9 OWF48383.1 - 2.5e-45 155.1 6.5 2.5e-40 138.7 2.8 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 OWF48383.1 - 8.8e-25 87.9 0.3 8.8e-25 87.9 0.3 2.9 3 0 0 3 3 3 1 Telomerase activating protein Est1 PIN_4 PF13638.6 OWF48383.1 - 3.7e-08 33.7 0.1 2.2e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 PIN domain TPR_14 PF13428.6 OWF48383.1 - 0.16 12.9 0.4 37 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TLE_N PF03920.15 OWF48384.1 - 2.9e-72 240.9 7.6 4.9e-72 240.2 7.6 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 OWF48384.1 - 3.7e-17 62.4 19.5 0.0016 19.3 0.5 7.7 8 0 0 8 8 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF48384.1 - 2.8e-08 33.9 0.0 0.47 10.8 0.0 4.7 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF48384.1 - 0.0089 15.4 0.0 4.3 6.6 0.0 2.6 2 1 1 3 3 3 2 WD40-like domain Transketolase_N PF00456.21 OWF48384.1 - 0.0096 14.9 0.1 0.017 14.1 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain HAP1_N PF04849.13 OWF48384.1 - 0.011 15.0 1.3 0.022 14.0 1.3 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HALZ PF02183.18 OWF48384.1 - 0.015 15.5 0.1 0.015 15.5 0.1 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cytochrom_D1 PF02239.16 OWF48384.1 - 0.098 11.2 0.0 4.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Spc24 PF08286.11 OWF48384.1 - 0.11 12.8 0.4 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Nup160 PF11715.8 OWF48384.1 - 0.13 10.9 0.2 2.8 6.5 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SKA2 PF16740.5 OWF48384.1 - 2.1 8.1 6.4 1.2 9.0 3.7 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 C1q PF00386.21 OWF48385.1 - 4.6e-21 75.3 0.0 5.1e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF48385.1 - 1.7e-06 28.0 0.2 1.9e-06 27.8 0.2 1.1 1 0 0 1 1 1 1 BclA C-terminal domain zf-C3HC4_2 PF13923.6 OWF48386.1 - 4.1e-08 32.9 8.6 9.4e-08 31.8 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF48386.1 - 6.2e-07 29.2 8.0 1.7e-06 27.8 8.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF48386.1 - 7.2e-07 29.0 6.0 1.6e-06 27.8 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF48386.1 - 9.4e-07 29.1 8.8 3.1e-06 27.4 8.8 2.0 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OWF48386.1 - 0.00023 21.0 7.1 0.00063 19.5 7.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OWF48386.1 - 0.00072 19.6 2.3 0.0019 18.2 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OWF48386.1 - 0.00078 19.7 5.9 0.0036 17.6 5.9 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF48386.1 - 0.004 17.2 3.7 0.0068 16.4 2.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF48386.1 - 0.0045 16.9 8.5 0.01 15.8 8.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 OWF48386.1 - 0.085 13.0 5.6 0.23 11.6 5.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OWF48386.1 - 0.55 10.4 8.2 1.8 8.8 8.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OWF48386.1 - 5.6 6.8 7.5 15 5.5 7.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SNF2_N PF00176.23 OWF48387.1 - 3.2e-44 151.1 0.0 5.6e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF48387.1 - 6.2e-19 68.4 0.0 8e-18 64.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF48387.1 - 1.3e-07 31.8 0.0 8.2e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit VIGSSK PF14773.6 OWF48387.1 - 1.3e-06 28.5 0.3 2.3e-05 24.4 0.0 2.9 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal HDA2-3 PF11496.8 OWF48387.1 - 7.7e-05 22.0 0.0 0.00047 19.4 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SMN PF06003.12 OWF48387.1 - 0.00094 18.5 0.1 0.00094 18.5 0.1 2.8 3 0 0 3 3 3 1 Survival motor neuron protein (SMN) ERCC3_RAD25_C PF16203.5 OWF48387.1 - 0.0063 15.8 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Syndecan PF01034.20 OWF48388.1 - 0.034 14.1 0.5 0.067 13.1 0.1 1.6 2 0 0 2 2 2 0 Syndecan domain Adeno_E3_CR2 PF02439.15 OWF48388.1 - 0.73 9.6 2.1 1.4 8.7 2.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ctr PF04145.15 OWF48389.1 - 5e-16 59.6 7.4 4.7e-15 56.5 7.4 2.0 1 1 0 1 1 1 1 Ctr copper transporter family FGE-sulfatase PF03781.16 OWF48391.1 - 3.2e-33 115.4 1.5 4.5e-32 111.6 1.5 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OWF48391.1 - 3.5e-06 27.5 0.0 7.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 DinB superfamily Forkhead PF00250.18 OWF48392.1 - 9.4e-38 128.4 0.0 1.8e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Polysacc_deac_1 PF01522.21 OWF48393.1 - 6.7e-06 26.0 0.0 0.00015 21.7 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide deacetylase TGT PF01702.18 OWF48393.1 - 0.067 12.3 0.0 0.39 9.8 0.0 1.9 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase DUF2334 PF10096.9 OWF48393.1 - 0.071 12.8 0.9 3.6 7.2 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Forkhead PF00250.18 OWF48394.1 - 2.7e-36 123.7 0.1 5.5e-36 122.7 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain COX5A PF02284.16 OWF48395.1 - 5.1e-24 84.2 0.0 7.5e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va AAA_lid_7 PF17867.1 OWF48395.1 - 0.13 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Midasin AAA lid domain Arrestin_C PF02752.22 OWF48396.1 - 8.8e-29 100.7 0.0 2.8e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF48396.1 - 7.2e-23 81.3 0.4 1.6e-22 80.1 0.4 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OWF48396.1 - 0.00026 20.3 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 Rgp1 sCache_2 PF17200.4 OWF48396.1 - 0.021 14.7 0.4 0.037 13.9 0.4 1.3 1 0 0 1 1 1 0 Single Cache domain 2 LDB19 PF13002.7 OWF48396.1 - 0.037 13.7 0.0 0.095 12.4 0.0 1.7 1 1 0 1 1 1 0 Arrestin_N terminal like Viral_Rep PF02407.16 OWF48396.1 - 0.12 12.6 0.2 0.26 11.6 0.2 1.5 1 0 0 1 1 1 0 Putative viral replication protein NICE-3 PF07406.11 OWF48397.1 - 9.4e-49 165.8 0.0 1.3e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein Ank_2 PF12796.7 OWF48399.1 - 4.4e-52 174.6 25.2 3e-14 53.4 0.6 6.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF48399.1 - 1.3e-41 140.1 10.7 5.7e-09 36.1 0.1 7.2 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF48399.1 - 8.5e-36 121.9 9.2 1.7e-07 31.6 0.1 9.5 2 2 9 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF48399.1 - 3.6e-35 118.9 21.3 0.00017 21.9 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 OWF48399.1 - 4.8e-32 106.4 13.2 0.0016 18.8 0.0 11.2 11 0 0 11 11 11 7 Ankyrin repeat Mab-21 PF03281.14 OWF48399.1 - 2e-10 40.4 0.0 2.1e-06 27.3 0.0 3.3 2 1 0 2 2 2 2 Mab-21 protein Aldose_epim PF01263.20 OWF48400.1 - 2.4e-42 145.3 0.1 2.7e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase LicD PF04991.13 OWF48401.1 - 5.3e-18 66.0 0.3 1.1e-16 61.7 0.1 2.1 1 1 1 2 2 2 2 LicD family LicD PF04991.13 OWF48402.1 - 6e-13 49.5 7.1 6e-12 46.2 0.5 3.0 2 1 1 3 3 3 2 LicD family Nnf1 PF03980.14 OWF48403.1 - 1.4e-11 44.7 5.3 1.4e-11 44.7 5.3 2.0 2 0 0 2 2 2 1 Nnf1 Osteoregulin PF07175.11 OWF48403.1 - 0.0078 16.4 0.9 0.013 15.8 0.9 1.5 1 0 0 1 1 1 1 Osteoregulin LicD PF04991.13 OWF48404.1 - 1.1e-18 68.3 6.4 1.6e-13 51.3 1.0 3.4 2 1 1 3 3 3 3 LicD family Aldedh PF00171.22 OWF48405.1 - 7.6e-182 604.9 0.0 8.6e-182 604.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OWF48405.1 - 0.16 11.0 0.1 0.72 8.8 0.1 2.1 2 1 0 2 2 2 0 Acyl-CoA reductase (LuxC) ANAPC4_WD40 PF12894.7 OWF48406.1 - 2.4e-07 31.0 0.1 0.54 10.6 0.0 5.1 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF48406.1 - 3.6e-07 30.8 7.7 1.6 9.7 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OWF48406.1 - 0.0014 17.7 0.0 0.0029 16.6 0.0 1.5 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 OWF48406.1 - 0.032 13.5 0.2 3.2 6.9 0.2 2.6 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF4191 PF13829.6 OWF48406.1 - 0.045 13.1 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FAM219A PF15260.6 OWF48407.1 - 3.3e-22 79.2 3.1 3.3e-22 79.2 3.1 1.7 1 1 1 2 2 2 1 Protein family FAM219A Aldedh PF00171.22 OWF48408.1 - 1.5e-180 600.6 0.0 1.5e-180 600.6 0.0 2.7 2 1 1 3 3 3 1 Aldehyde dehydrogenase family WEMBL PF05701.11 OWF48408.1 - 7.2e-11 41.5 25.3 1.4e-07 30.6 9.9 2.0 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Spc7 PF08317.11 OWF48408.1 - 3.9e-05 22.7 2.5 0.019 13.9 0.4 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein YscO PF07321.12 OWF48408.1 - 0.00011 22.2 13.7 0.013 15.5 6.0 2.8 1 1 2 3 3 3 3 Type III secretion protein YscO COG2 PF06148.11 OWF48408.1 - 0.0018 18.3 3.4 12 6.0 0.1 4.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 EzrA PF06160.12 OWF48408.1 - 0.0027 16.0 0.2 1.7 6.7 0.0 2.1 1 1 0 2 2 2 2 Septation ring formation regulator, EzrA DUF745 PF05335.13 OWF48408.1 - 0.0057 16.4 14.3 0.0057 16.4 14.3 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF745) Atg14 PF10186.9 OWF48408.1 - 0.0086 15.2 25.4 0.32 10.0 11.9 2.4 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 OWF48408.1 - 0.012 15.7 14.5 0.11 12.5 4.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 OWF48408.1 - 0.014 15.0 7.0 0.41 10.1 2.7 2.7 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Filament PF00038.21 OWF48408.1 - 0.016 14.8 16.3 1.3 8.6 2.4 3.1 1 1 1 2 2 2 0 Intermediate filament protein FliJ PF02050.16 OWF48408.1 - 0.022 15.0 15.1 0.8 9.9 2.3 3.2 1 1 1 2 2 2 0 Flagellar FliJ protein Cue1_U7BR PF18499.1 OWF48408.1 - 0.061 13.4 0.1 1.5e+02 2.5 0.0 5.5 5 4 4 9 9 9 0 Ubc7p-binding region of Cue1 OEP PF02321.18 OWF48408.1 - 0.1 12.4 3.6 6.2 6.6 0.7 3.5 1 1 1 2 2 2 0 Outer membrane efflux protein DUF2846 PF11008.8 OWF48408.1 - 0.15 12.1 1.2 0.96 9.5 0.0 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF2846) AAA_13 PF13166.6 OWF48408.1 - 0.15 10.7 10.5 0.22 10.2 10.5 1.1 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 OWF48408.1 - 0.28 11.0 9.1 3.6 7.4 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HrpB7 PF09486.10 OWF48408.1 - 0.62 10.4 27.9 7 7.0 22.5 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) YqjK PF13997.6 OWF48408.1 - 0.77 10.0 9.8 27 5.1 0.3 4.0 1 1 3 4 4 4 0 YqjK-like protein USP8_interact PF08941.10 OWF48408.1 - 1.2 8.9 12.7 8.2 6.2 1.4 3.6 1 1 3 4 4 4 0 USP8 interacting Fez1 PF06818.15 OWF48408.1 - 2.7 8.4 6.2 8.5 6.8 6.2 1.8 1 1 0 1 1 1 0 Fez1 AIP3 PF03915.13 OWF48408.1 - 4.8 6.2 16.1 2.7e+02 0.4 16.1 2.2 1 1 0 1 1 1 0 Actin interacting protein 3 DUF3584 PF12128.8 OWF48408.1 - 5.6 4.3 16.2 9.1 3.6 6.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Aldedh PF00171.22 OWF48409.1 - 1.1e-179 597.8 0.0 1.3e-179 597.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family VWA PF00092.28 OWF48410.1 - 5.7e-14 52.7 0.1 7e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48410.1 - 1.2e-06 29.1 0.0 2.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Toprim_3 PF13362.6 OWF48410.1 - 0.027 14.8 0.4 0.098 13.0 0.1 1.9 2 0 0 2 2 2 0 Toprim domain VWA_3 PF13768.6 OWF48410.1 - 0.029 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 OWF48411.1 - 4.3e-28 98.7 11.2 1e-20 74.7 1.3 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48411.1 - 1.8e-06 28.6 1.2 0.014 16.0 0.0 3.0 2 1 0 3 3 3 2 von Willebrand factor type A domain FleQ PF06490.11 OWF48411.1 - 0.011 16.1 0.0 0.069 13.5 0.0 2.1 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Daxx PF03344.15 OWF48411.1 - 0.075 13.1 0.1 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain VWA PF00092.28 OWF48412.1 - 2.4e-89 298.2 3.7 1.4e-41 142.7 0.2 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48412.1 - 5.9e-33 113.7 0.9 5.7e-16 59.1 0.0 3.8 4 0 0 4 4 4 2 von Willebrand factor type A domain VWA_3 PF13768.6 OWF48412.1 - 5.8e-11 42.6 0.0 8.9e-06 25.7 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF48412.1 - 6.2e-07 29.0 0.1 0.00053 19.4 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 OWF48412.1 - 9.7e-05 22.6 0.6 0.01 16.0 0.1 2.4 2 0 0 2 2 2 1 vWA found in TerF C terminus Copine PF07002.16 OWF48412.1 - 0.00024 20.7 0.0 0.71 9.3 0.0 2.4 2 0 0 2 2 2 2 Copine Integrin_beta PF00362.18 OWF48412.1 - 0.014 15.1 0.1 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Integrin beta chain VWA domain DUF2659 PF10858.8 OWF48412.1 - 0.035 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) VWA PF00092.28 OWF48414.1 - 5.2e-50 170.1 1.7 2.3e-36 125.6 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48414.1 - 7.6e-14 52.3 0.0 3.1e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF48414.1 - 7.9e-07 29.1 0.0 0.0059 16.5 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain AhpC-TSA_2 PF13911.6 OWF48414.1 - 0.065 13.4 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme SAM_decarbox PF01536.16 OWF48414.1 - 0.089 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase VWA PF00092.28 OWF48415.1 - 6.1e-47 160.1 7.6 5.9e-35 121.1 0.2 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48415.1 - 1.2e-12 48.4 0.3 3.8e-11 43.6 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF48415.1 - 1.4e-07 31.6 0.1 0.0039 17.1 0.0 3.3 2 1 1 3 3 3 2 von Willebrand factor type A domain Copine PF07002.16 OWF48415.1 - 0.0063 16.0 0.2 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 Copine Integrin_beta PF00362.18 OWF48415.1 - 0.08 12.6 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 Integrin beta chain VWA domain VWA PF00092.28 OWF48416.1 - 1.5e-43 149.1 2.6 1.8e-34 119.5 0.1 2.3 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48416.1 - 3e-11 43.9 0.0 4.7e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF48416.1 - 8.6e-05 22.5 0.0 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 OWF48416.1 - 0.015 15.4 0.2 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 vWA found in TerF C terminus VWA_CoxE PF05762.14 OWF48416.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.5 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DUF1319 PF07028.11 OWF48416.1 - 0.089 13.0 0.3 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) AhpC-TSA_2 PF13911.6 OWF48416.1 - 0.094 12.8 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme Coagulin PF02035.15 OWF48416.1 - 0.17 11.8 0.0 0.87 9.5 0.0 1.9 2 0 0 2 2 2 0 Coagulin VWA PF00092.28 OWF48417.1 - 9.2e-55 185.6 3.4 5.9e-34 117.8 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48417.1 - 3.4e-15 56.6 0.1 6.7e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OWF48417.1 - 0.00054 19.9 0.0 0.002 18.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF48417.1 - 0.0026 17.2 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Ins134_P3_kin PF05770.11 OWF48417.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain AhpC-TSA_2 PF13911.6 OWF48417.1 - 0.094 12.8 1.1 19 5.4 0.0 2.7 3 0 0 3 3 3 0 AhpC/TSA antioxidant enzyme VWA PF00092.28 OWF48418.1 - 2.2e-93 311.4 12.7 8.3e-45 153.2 0.8 4.0 3 1 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48418.1 - 1.2e-33 115.9 2.0 2.7e-16 60.1 0.1 2.9 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 OWF48418.1 - 5.7e-11 42.6 0.0 0.0003 20.8 0.0 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain vWA-TerF-like PF10138.9 OWF48418.1 - 1.2e-07 32.0 2.4 0.0049 17.0 0.4 2.3 2 0 0 2 2 2 2 vWA found in TerF C terminus Copine PF07002.16 OWF48418.1 - 1.1e-05 25.0 0.0 0.045 13.2 0.0 2.3 2 0 0 2 2 2 2 Copine Rgp1 PF08737.10 OWF48418.1 - 0.012 14.9 0.0 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Rgp1 T3SS_basalb_I PF17001.5 OWF48418.1 - 0.12 13.0 0.0 0.31 11.7 0.0 1.7 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI ASFV_J13L PF05568.11 OWF48418.1 - 0.26 11.0 10.9 0.53 10.0 10.5 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein VWA PF00092.28 OWF48419.1 - 8.7e-77 257.3 3.0 3.9e-35 121.7 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF48419.1 - 2.1e-27 95.8 0.1 1.4e-12 48.2 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OWF48419.1 - 4.6e-09 36.4 0.0 0.0026 17.7 0.0 2.9 2 1 0 2 2 2 2 von Willebrand factor type A domain WD40 PF00400.32 OWF48420.1 - 1.8e-27 95.0 22.0 2e-06 28.4 0.3 8.7 9 1 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF48420.1 - 7.8e-10 38.9 0.1 0.0049 17.1 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SLC12 PF03522.15 OWF48421.1 - 6.3e-145 483.5 6.5 6.5e-145 483.4 0.7 2.6 2 1 0 2 2 2 1 Solute carrier family 12 AA_permease PF00324.21 OWF48421.1 - 8.8e-114 380.7 38.6 1.1e-113 380.4 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.10 OWF48421.1 - 1.1e-10 40.8 0.2 2.9e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Amino acid permease N-terminal FIST_C PF10442.9 OWF48422.1 - 3.2e-11 43.3 0.1 8.2e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 FIST C domain F-box PF00646.33 OWF48422.1 - 1.6e-06 27.9 0.5 4.1e-06 26.5 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OWF48422.1 - 0.0023 17.8 0.2 0.0056 16.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like Utp13 PF08625.11 OWF48422.1 - 0.075 12.9 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain LZ3wCH PF18517.1 OWF48423.1 - 0.074 13.2 1.3 0.19 11.8 1.3 1.8 1 0 0 1 1 1 0 Leucine zipper with capping helix domain DUF4649 PF15507.6 OWF48423.1 - 0.13 12.3 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) SlyX PF04102.12 OWF48423.1 - 0.54 10.9 25.2 0.3 11.7 1.3 4.6 2 1 2 4 4 4 0 SlyX Tuberculin PF12198.8 OWF48423.1 - 1.8 8.7 5.0 6.4 7.0 3.4 2.4 2 0 0 2 2 2 0 Theoretical tuberculin protein DAO PF01266.24 OWF48424.1 - 7e-43 147.5 0.0 8e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF48424.1 - 0.00047 20.3 0.2 0.0012 19.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OWF48424.1 - 0.0032 16.8 0.0 0.0065 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF48424.1 - 0.0051 16.2 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OWF48424.1 - 0.0063 17.0 0.8 0.091 13.3 0.1 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF48424.1 - 0.0082 15.3 0.1 0.02 14.0 0.2 1.6 1 1 1 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 OWF48424.1 - 0.011 15.0 0.3 0.041 13.1 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 OWF48424.1 - 0.04 13.2 0.2 0.086 12.1 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OWF48424.1 - 0.048 12.7 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.22 OWF48425.1 - 3.4e-16 58.8 0.1 5.6e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF48425.1 - 0.00022 20.8 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF48425.1 - 0.0017 18.4 0.2 0.0077 16.3 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif GIDE PF12483.8 OWF48426.1 - 0.047 13.1 0.9 6.9 6.0 0.1 2.7 1 1 1 2 2 2 0 E3 Ubiquitin ligase MF_alpha PF04648.12 OWF48426.1 - 0.3 11.4 11.6 54 4.3 0.1 5.5 5 0 0 5 5 5 0 Yeast mating factor alpha hormone YEATS PF03366.16 OWF48427.1 - 9.1e-24 83.2 0.1 1.8e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 YEATS family AHD PF17793.1 OWF48427.1 - 1.6e-21 75.9 0.8 2.8e-21 75.1 0.8 1.4 1 0 0 1 1 1 1 ANC1 homology domain (AHD) S36_mt PF10937.8 OWF48428.1 - 1.2e-07 33.3 0.4 2.5e-07 32.3 0.4 1.6 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Peptidase_S8 PF00082.22 OWF48429.1 - 6.6e-44 150.3 1.6 1e-43 149.7 1.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OWF48429.1 - 2.5e-26 91.5 0.1 4.7e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OWF48429.1 - 4e-24 85.2 0.9 7.2e-24 84.4 0.9 1.4 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like PF00757.20 OWF48429.1 - 3.4e-09 36.7 30.6 3.4e-09 36.7 30.6 4.5 2 1 2 4 4 4 2 Furin-like cysteine rich region GF_recep_IV PF14843.6 OWF48429.1 - 6.6e-07 29.2 103.3 2.2e-05 24.2 18.4 4.7 1 1 3 4 4 4 2 Growth factor receptor domain IV Furin-like_2 PF15913.5 OWF48429.1 - 2.6e-06 27.6 32.0 4e-06 26.9 12.0 6.1 1 1 5 6 6 6 4 Furin-like repeat, cysteine-rich Orf78 PF06024.12 OWF48429.1 - 0.023 15.0 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) VSP PF03302.13 OWF48429.1 - 0.15 10.8 88.3 0.0055 15.6 56.0 3.7 1 1 2 3 3 3 0 Giardia variant-specific surface protein Arch_flagellin PF01917.16 OWF48429.1 - 0.67 10.1 4.1 7.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Archaebacterial flagellin Sec1 PF00995.23 OWF48430.1 - 8.7e-134 447.9 0.6 1e-133 447.6 0.6 1.1 1 0 0 1 1 1 1 Sec1 family TNF PF00229.18 OWF48430.1 - 0.044 13.7 0.4 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family GRIM-19 PF06212.12 OWF48431.1 - 3.7e-36 124.0 0.0 4.4e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein wnt PF00110.19 OWF48432.1 - 1.9e-115 385.7 27.5 2.1e-115 385.5 27.5 1.0 1 0 0 1 1 1 1 wnt family DUF620 PF04788.12 OWF48432.1 - 0.078 12.4 0.5 0.38 10.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF620) DUF4601 PF15373.6 OWF48433.1 - 3.2e-14 52.7 12.1 2.3e-13 50.0 12.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4601) DUF4719 PF15843.5 OWF48434.1 - 5 7.2 6.4 0.46 10.6 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) CALM_bind PF16025.5 OWF48434.1 - 7.6 7.1 10.4 0.6 10.6 3.4 3.0 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding YcgR_2 PF12945.7 OWF48435.1 - 0.11 12.7 0.0 2.5 8.3 0.0 2.3 1 1 1 2 2 2 0 Flagellar protein YcgR Pro-kuma_activ PF09286.11 OWF48435.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 1 1 2 2 2 0 Pro-kumamolisin, activation domain DUF4558 PF15104.6 OWF48437.1 - 6.8e-18 64.5 7.5 6.8e-18 64.5 7.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) Guanylate_cyc_2 PF09778.9 OWF48437.1 - 0.0011 18.4 1.5 0.0069 15.8 0.3 2.0 1 1 1 2 2 2 1 Guanylylate cyclase CAF-1_p150 PF11600.8 OWF48437.1 - 0.0028 17.4 9.7 0.0035 17.0 9.7 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Vfa1 PF08432.10 OWF48437.1 - 0.15 12.3 7.8 0.19 12.1 7.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1151 PF06625.11 OWF48437.1 - 0.21 11.5 11.5 0.13 12.2 8.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) zf-C2HE PF16278.5 OWF48439.1 - 0.0093 16.4 1.5 50 4.4 1.5 5.8 3 3 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_UBOX PF13445.6 OWF48440.1 - 4.3e-13 49.0 4.6 4.3e-13 49.0 4.6 1.9 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF48440.1 - 2.5e-10 40.3 7.4 2.5e-10 40.3 7.4 2.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF48440.1 - 7.8e-10 38.5 8.9 7.8e-10 38.5 8.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF48440.1 - 3e-09 37.1 8.1 3e-09 37.1 8.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF48440.1 - 7.2e-08 32.1 14.7 5.5e-07 29.3 11.9 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF48440.1 - 1.3e-07 31.4 7.5 1.3e-07 31.4 7.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF48440.1 - 9.1e-07 28.6 11.2 1.1e-06 28.3 7.8 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OWF48440.1 - 0.002 17.9 7.0 0.0044 16.8 7.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OWF48440.1 - 0.011 15.4 8.0 0.011 15.4 8.0 1.8 2 0 0 2 2 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 OWF48440.1 - 0.082 12.8 18.0 0.39 10.6 14.5 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF48440.1 - 0.23 11.3 10.0 0.28 11.0 7.2 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain FlhC PF05280.11 OWF48440.1 - 0.24 11.1 5.6 0.15 11.8 1.8 2.0 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) Zn-C2H2_12 PF18112.1 OWF48440.1 - 0.49 10.9 0.4 0.49 10.9 0.4 3.5 3 1 1 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_6 PF14835.6 OWF48440.1 - 0.86 9.5 6.6 3 7.8 6.6 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-WRNIP1_ubi PF18279.1 OWF48440.1 - 2 9.2 6.6 8 7.4 0.4 3.4 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_4 PF13894.6 OWF48440.1 - 2.1 9.4 15.0 1.8 9.6 1.4 4.4 4 1 1 5 5 4 0 C2H2-type zinc finger zf-ANAPC11 PF12861.7 OWF48440.1 - 3.1 7.9 7.1 2.7 8.1 3.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OWF48440.1 - 4.4 7.7 11.8 5.3 7.4 8.9 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-met PF12874.7 OWF48440.1 - 7.9 7.0 10.1 7.2 7.2 0.3 3.8 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OWF48440.1 - 7.9 6.5 13.6 9.1 6.3 4.7 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-B_box PF00643.24 OWF48441.1 - 4e-05 23.7 20.3 0.00083 19.5 5.3 3.2 2 1 1 3 3 3 2 B-box zinc finger DUF2387 PF09526.10 OWF48441.1 - 0.01 16.0 1.0 0.01 16.0 1.0 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Baculo_PEP_C PF04513.12 OWF48441.1 - 0.024 14.7 5.3 0.38 10.8 5.3 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bac_GDH PF05088.12 OWF48441.1 - 0.042 11.3 0.8 0.062 10.8 0.8 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase HEPPP_synt_1 PF07307.11 OWF48441.1 - 0.067 12.8 0.3 0.067 12.8 0.3 1.6 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DUF1722 PF08349.11 OWF48441.1 - 0.22 11.8 0.9 0.83 10.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) Phasin PF05597.11 OWF48441.1 - 0.36 10.8 2.5 0.41 10.7 1.4 1.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HrcA_DNA-bdg PF03444.15 OWF48441.1 - 0.47 10.1 1.6 9.7 5.9 0.1 3.2 4 0 0 4 4 4 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Syntaxin_2 PF14523.6 OWF48441.1 - 0.52 10.7 6.8 0.54 10.7 4.5 2.1 1 1 1 2 2 2 0 Syntaxin-like protein CorA PF01544.18 OWF48441.1 - 0.57 9.4 3.3 0.79 9.0 3.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Alpha-mann_mid PF09261.11 OWF48441.1 - 0.66 10.2 2.2 3.8 7.7 0.1 2.9 3 0 0 3 3 3 0 Alpha mannosidase middle domain DUF16 PF01519.16 OWF48441.1 - 3.5 8.2 6.5 0.5 10.9 1.8 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 7tm_2 PF00002.24 OWF48442.1 - 1.3e-15 57.4 20.3 2.6e-15 56.4 20.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 OWF48442.1 - 2.8 8.4 26.7 0.42 11.1 12.9 3.1 2 0 0 2 2 2 0 Somatomedin B domain Sulfotransfer_1 PF00685.27 OWF48443.1 - 0.00038 20.0 0.3 0.16 11.4 0.0 2.0 1 1 1 2 2 2 2 Sulfotransferase domain ATP-grasp PF02222.22 OWF48444.1 - 0.0017 17.9 0.0 12 5.4 0.0 3.1 1 1 2 3 3 3 3 ATP-grasp domain T2SSL PF05134.13 OWF48444.1 - 0.093 12.1 0.5 2.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein L F5_F8_type_C PF00754.25 OWF48445.1 - 2.3e-07 31.0 0.1 3.8e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain Neur_chan_LBD PF02931.23 OWF48446.1 - 1.6e-23 83.3 0.0 2.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48446.1 - 9.1e-06 25.9 10.4 2.6e-05 24.4 5.1 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Dyp_perox PF04261.12 OWF48447.1 - 5.8e-41 140.5 0.2 7.5e-41 140.2 0.2 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family Tautomerase_3 PF14832.6 OWF48447.1 - 0.15 12.2 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Putative oxalocrotonate tautomerase enzyme DUF16 PF01519.16 OWF48448.1 - 1.2 9.6 9.5 20 5.7 0.3 4.3 1 1 2 4 4 4 0 Protein of unknown function DUF16 T2SSppdC PF12528.8 OWF48449.1 - 0.027 15.2 0.4 4.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Type II secretion prepilin peptidase dependent protein C WW_like PF17890.1 OWF48449.1 - 0.09 12.9 5.8 62 3.8 0.1 5.1 1 1 5 6 6 6 0 Peptidoglycan hydrolase LytB WW-like domain BTD PF09270.10 OWF48450.1 - 0.0002 21.6 0.3 6.1 7.1 0.0 4.2 1 1 3 4 4 4 2 Beta-trefoil DNA-binding domain Big_4 PF07532.11 OWF48450.1 - 0.0022 17.7 6.1 16 5.3 0.0 6.1 5 3 2 7 7 7 1 Bacterial Ig-like domain (group 4) Hfq PF17209.3 OWF48450.1 - 0.003 17.1 0.0 43 3.8 0.0 5.4 6 0 0 6 6 6 0 Hfq protein DUF2499 PF10693.9 OWF48450.1 - 0.0038 17.5 3.7 5.9 7.2 0.0 3.9 2 1 2 4 4 4 2 Protein of unknown function (DUF2499) Ribosomal_L26 PF16906.5 OWF48450.1 - 0.18 12.3 0.0 6.8 7.2 0.0 2.8 1 1 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal T2SSppdC PF12528.8 OWF48450.1 - 0.21 12.4 9.7 5.4 7.9 0.5 4.0 4 0 0 4 4 4 0 Type II secretion prepilin peptidase dependent protein C RBD PF02196.15 OWF48450.1 - 2 8.6 5.0 93 3.2 0.0 4.8 3 1 2 5 5 5 0 Raf-like Ras-binding domain WW_like PF17890.1 OWF48450.1 - 4.3 7.5 16.4 41 4.3 0.6 6.5 4 2 4 8 8 8 0 Peptidoglycan hydrolase LytB WW-like domain DUF2135 PF09906.9 OWF48450.1 - 4.8 7.6 7.6 1.3e+02 3.0 0.4 4.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) Homeodomain PF00046.29 OWF48451.1 - 6.8e-21 73.9 4.7 1.1e-20 73.2 4.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF48451.1 - 0.023 14.6 0.2 0.023 14.6 0.2 1.8 2 0 0 2 2 2 0 Homeobox KN domain Polyketide_cyc PF03364.20 OWF48451.1 - 0.14 12.4 0.2 0.19 11.9 0.2 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Prominin PF05478.11 OWF48452.1 - 1.2e-73 248.5 11.1 3.1e-42 144.5 1.4 2.2 1 1 1 2 2 2 2 Prominin Na_Ca_ex PF01699.24 OWF48452.1 - 0.00052 20.0 5.6 0.28 11.1 0.4 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Baculo_PEP_C PF04513.12 OWF48452.1 - 0.00067 19.7 40.6 0.079 13.0 6.1 5.0 2 2 2 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus HemX PF04375.14 OWF48452.1 - 0.0071 15.7 0.2 0.0071 15.7 0.2 2.8 3 1 0 3 3 3 1 HemX, putative uroporphyrinogen-III C-methyltransferase Med9 PF07544.13 OWF48452.1 - 0.026 14.6 2.7 2.5 8.2 0.0 3.7 3 1 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Apolipoprotein PF01442.18 OWF48452.1 - 0.06 13.2 3.1 9.2 6.1 0.0 3.5 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain ApoO PF09769.9 OWF48452.1 - 0.061 13.3 0.5 1.6 8.7 0.1 3.2 2 1 1 3 3 3 0 Apolipoprotein O MdcG PF10620.9 OWF48452.1 - 0.092 12.5 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG COG2 PF06148.11 OWF48452.1 - 0.12 12.5 1.7 11 6.2 0.2 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Myosin_tail_1 PF01576.19 OWF48452.1 - 0.25 9.1 0.7 1.7 6.4 0.1 2.0 2 0 0 2 2 2 0 Myosin tail DASH_Duo1 PF08651.10 OWF48452.1 - 0.6 9.9 3.9 3.4 7.5 0.3 3.6 3 1 0 3 3 3 0 DASH complex subunit Duo1 V-SNARE PF05008.15 OWF48452.1 - 0.64 10.4 3.3 11 6.5 0.0 4.0 4 1 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.11 OWF48452.1 - 0.85 10.2 9.7 2.9 8.5 0.1 4.3 4 1 1 5 5 5 0 Syntaxin 6, N-terminal Phasin PF05597.11 OWF48452.1 - 0.9 9.6 4.6 17 5.4 0.3 3.5 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.12 OWF48452.1 - 0.94 10.0 33.3 0.46 11.0 4.6 6.0 4 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.12 OWF48452.1 - 1.1 9.5 12.7 1.8 8.8 0.2 4.0 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Tape_meas_lam_C PF09718.10 OWF48452.1 - 1.5 9.1 4.7 0.56 10.4 0.3 2.5 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phage_GP20 PF06810.11 OWF48452.1 - 2.1 8.2 24.2 0.59 9.9 1.4 4.5 4 2 1 5 5 5 0 Phage minor structural protein GP20 HalX PF08663.10 OWF48452.1 - 2.3 8.6 4.2 49 4.3 0.0 4.0 5 1 0 5 5 5 0 HalX domain LXG PF04740.12 OWF48452.1 - 2.5 7.8 16.0 0.64 9.7 0.8 3.6 3 0 0 3 3 3 0 LXG domain of WXG superfamily DUF3502 PF12010.8 OWF48452.1 - 4.5 7.9 5.6 39 4.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3502) AlbA_2 PF04326.14 OWF48453.1 - 1e-12 48.4 0.1 2.3e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 Putative DNA-binding domain DUF2075 PF09848.9 OWF48453.1 - 1.2e-06 28.1 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_12 PF13087.6 OWF48453.1 - 0.00023 20.8 0.0 0.0005 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OWF48453.1 - 0.00032 20.7 0.1 0.0088 16.1 0.0 2.9 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 OWF48453.1 - 0.00038 20.5 0.0 0.00089 19.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OWF48453.1 - 0.00041 20.2 0.1 0.0021 17.9 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF48453.1 - 0.00042 20.6 0.0 0.0064 16.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OWF48453.1 - 0.00044 20.6 0.8 0.014 15.8 0.0 3.0 2 1 1 3 3 3 1 RNA helicase AAA PF00004.29 OWF48453.1 - 0.0017 18.8 0.0 0.0059 17.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OWF48453.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OWF48453.1 - 0.0051 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 OWF48453.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OWF48453.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OWF48453.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OWF48453.1 - 0.035 14.7 0.0 0.093 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF48453.1 - 0.049 14.0 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain AAA_24 PF13479.6 OWF48453.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OWF48453.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PRANC PF09372.10 OWF48453.1 - 0.12 12.7 0.6 4.2 7.8 1.7 2.7 2 0 0 2 2 2 0 PRANC domain DUF3781 PF12636.7 OWF48453.1 - 0.54 10.2 4.9 28 4.7 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CoA_binding PF02629.19 OWF48454.1 - 1.6e-28 99.3 2.9 1.7e-28 99.2 0.6 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OWF48454.1 - 5.8e-23 81.4 0.1 9.5e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OWF48454.1 - 1.2e-07 31.6 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OWF48454.1 - 0.00042 20.8 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain zf-CHY PF05495.12 OWF48455.1 - 4.9 7.7 8.1 0.12 12.9 1.2 1.8 2 0 0 2 2 2 0 CHY zinc finger Raffinose_syn PF05691.12 OWF48456.1 - 3.3e-16 58.3 102.6 8.7 4.0 0.1 41.7 4 3 58 66 66 66 49 Raffinose synthase or seed imbibition protein Sip1 BppL_N PF18338.1 OWF48456.1 - 0.48 10.3 1.3 9.1e+02 -0.1 0.0 6.2 4 0 0 4 4 4 0 Lower baseplate protein N-terminal domain EF-hand_7 PF13499.6 OWF48457.1 - 8.9e-18 64.5 4.2 8.2e-12 45.4 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF48457.1 - 2.5e-16 57.9 3.3 1.1e-07 30.9 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF48457.1 - 9.2e-13 47.0 2.0 0.0073 16.2 0.1 4.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 OWF48457.1 - 6.3e-11 42.0 6.6 2.5e-10 40.0 0.4 3.4 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OWF48457.1 - 3.6e-09 36.8 0.1 2.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF48457.1 - 0.00013 21.3 0.1 0.014 14.9 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_11 PF08976.11 OWF48457.1 - 0.00053 20.8 0.4 0.15 12.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF48457.1 - 0.033 14.2 1.1 0.039 13.9 0.3 1.5 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 OWF48458.1 - 1.7e-41 136.7 14.6 8.7e-10 37.4 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF48458.1 - 2.4e-36 124.0 5.4 1.6e-18 66.9 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF48458.1 - 9.6e-32 108.6 14.9 7.8e-16 57.7 1.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF48458.1 - 5.1e-31 103.9 8.1 1.7e-09 36.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF48458.1 - 4.1e-27 92.4 9.9 7e-07 28.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF48458.1 - 1.1e-16 60.9 0.5 1.9e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF48458.1 - 7.5e-10 38.7 1.0 0.00013 21.9 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF48458.1 - 5.1e-08 33.2 0.1 0.0084 16.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF48458.1 - 1.1e-05 26.3 0.1 0.0035 18.2 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 OWF48458.1 - 4.5e-05 23.4 0.0 0.14 12.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 OWF48458.1 - 0.00027 19.6 0.0 0.0003 19.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 OWF48458.1 - 0.00032 20.8 3.9 0.29 11.4 0.3 2.8 1 1 2 3 3 3 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 OWF48458.1 - 0.00056 19.9 0.4 0.0066 16.5 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 OWF48458.1 - 0.00065 19.7 1.7 0.45 10.4 0.0 3.5 1 1 2 3 3 3 1 Caleosin related protein DUF4497 PF14924.6 OWF48458.1 - 0.001 19.5 0.0 1.4 9.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 OWF48458.1 - 0.0017 18.7 0.8 0.67 10.3 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 MotA_activ PF09114.10 OWF48458.1 - 0.0033 17.5 0.1 0.1 12.7 0.0 2.3 2 1 0 2 2 2 1 Transcription factor MotA, activation domain TerB PF05099.13 OWF48458.1 - 0.0035 17.3 0.3 0.16 11.9 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB Spore_III_AB PF09548.10 OWF48458.1 - 0.0046 17.1 0.1 0.0058 16.7 0.1 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) DUF3349 PF11829.8 OWF48458.1 - 0.0055 17.4 0.5 6.8 7.5 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) dCache_2 PF08269.11 OWF48458.1 - 0.0086 15.3 0.1 0.7 9.0 0.0 2.1 1 1 1 2 2 2 1 Cache domain DUF1103 PF06513.11 OWF48458.1 - 0.039 13.6 1.7 0.043 13.4 1.7 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) EF-hand_14 PF17959.1 OWF48458.1 - 0.04 14.2 0.2 5.9 7.3 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 OWF48458.1 - 0.049 13.5 0.5 0.68 9.8 0.2 2.1 1 1 1 2 2 2 0 SurA N-terminal domain AAA_assoc_C PF09821.9 OWF48458.1 - 0.065 13.8 0.5 0.96 10.0 0.1 2.3 2 1 0 2 2 2 0 C-terminal AAA-associated domain TetR_C_7 PF14246.6 OWF48458.1 - 0.12 12.4 0.0 4.7 7.3 0.0 2.4 1 1 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Extensin_2 PF04554.13 OWF48459.1 - 0.17 11.9 23.3 57 3.9 9.1 3.8 1 1 2 3 3 3 0 Extensin-like region Keratin_B2_2 PF13885.6 OWF48459.1 - 0.4 10.7 2.6 19 5.3 0.1 3.2 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein 7tm_1 PF00001.21 OWF48460.1 - 1.1e-20 74.1 12.0 1.8e-20 73.4 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF898 PF05987.13 OWF48460.1 - 0.0038 16.3 3.9 0.0038 16.3 3.9 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) GSAP-16 PF14959.6 OWF48460.1 - 1.6 8.6 0.0 1.6 8.6 0.0 3.1 3 1 0 3 3 3 0 gamma-Secretase-activating protein C-term 7tm_1 PF00001.21 OWF48461.1 - 9.9e-55 185.7 19.9 1.2e-54 185.4 19.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF48461.1 - 2.9e-13 49.8 19.8 5.3e-13 48.9 19.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF48461.1 - 2e-07 30.6 21.0 4.6e-07 29.4 21.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Gaa1 PF04114.14 OWF48461.1 - 0.0017 17.5 0.9 0.0017 17.5 0.9 2.0 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component Rab5ip PF07019.12 OWF48461.1 - 0.3 11.7 0.1 0.3 11.7 0.1 2.9 3 1 0 3 3 3 0 Rab5-interacting protein (Rab5ip) DUF2231 PF09990.9 OWF48461.1 - 1.4 9.4 6.3 0.45 11.0 0.9 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) Clc-like PF07062.12 OWF48462.1 - 0.0018 17.8 12.8 0.01 15.3 6.4 2.2 2 0 0 2 2 2 2 Clc-like DUF4514 PF14986.6 OWF48462.1 - 0.015 15.2 0.4 0.047 13.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) SSF PF00474.17 OWF48463.1 - 2.5e-06 26.6 3.1 3.3e-06 26.2 3.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Tetraspanin PF00335.20 OWF48463.1 - 0.67 9.6 4.0 1.8 8.2 4.0 1.6 1 1 1 2 2 2 0 Tetraspanin family zf-C2H2 PF00096.26 OWF48464.1 - 1.7e-48 160.4 195.0 0.00011 22.4 0.3 22.5 22 2 1 23 23 23 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF48464.1 - 1.8e-42 140.3 182.9 0.0024 18.6 3.3 22.2 24 0 0 24 24 24 20 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF48464.1 - 8.4e-34 114.5 147.4 1e-06 28.9 2.9 21.6 22 0 0 22 22 22 16 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF48464.1 - 2.6e-10 40.0 152.2 0.00025 20.9 0.4 20.2 22 0 0 22 22 22 13 C2H2-type zinc finger zf-met PF12874.7 OWF48464.1 - 4.3e-08 33.3 144.2 0.022 15.1 2.5 20.2 22 0 0 22 22 22 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF48464.1 - 1.9e-05 24.8 138.5 0.012 15.9 1.6 19.1 20 0 0 20 20 20 9 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 OWF48464.1 - 0.0018 18.0 25.6 0.41 10.5 1.0 8.4 6 2 4 10 10 10 3 GAGA factor zf-H2C2_5 PF13909.6 OWF48464.1 - 0.19 11.6 0.1 0.19 11.6 0.1 14.1 16 0 0 16 16 16 0 C2H2-type zinc-finger domain SSF PF00474.17 OWF48465.1 - 2.5e-40 138.6 28.6 3.5e-40 138.1 28.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Pox_A14 PF05767.12 OWF48465.1 - 0.038 14.2 0.2 0.038 14.2 0.2 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 MFS_1 PF07690.16 OWF48466.1 - 5.6e-19 68.3 30.7 5.6e-19 68.3 30.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ArsB PF02040.15 OWF48467.1 - 0.069 12.5 2.4 1e+02 2.1 0.0 5.0 4 1 2 6 6 6 0 Arsenical pump membrane protein DNA_gyraseA_C PF03989.13 OWF48467.1 - 0.11 12.0 0.1 1.6e+02 1.9 0.0 4.3 4 0 0 4 4 4 0 DNA gyrase C-terminal domain, beta-propeller C9orf72-like PF15019.6 OWF48467.1 - 3.1 7.3 14.5 91 2.5 0.1 6.1 3 3 2 7 7 7 0 C9orf72-like protein family Laminin_N PF00055.17 OWF48468.1 - 5.1e-82 275.0 2.4 5.1e-82 275.0 2.4 3.3 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) NTR PF01759.21 OWF48468.1 - 7.9e-27 93.2 0.8 2e-26 91.8 0.8 1.8 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 OWF48468.1 - 1.1e-20 73.5 73.6 9.3e-11 41.7 13.9 4.7 6 0 0 6 6 6 3 Laminin EGF domain COX5B PF01215.19 OWF48471.1 - 0.00043 20.0 7.3 52 3.5 0.0 6.7 2 2 2 6 6 6 4 Cytochrome c oxidase subunit Vb DUF3303 PF11746.8 OWF48471.1 - 0.057 13.7 0.3 60 4.0 0.0 4.5 2 1 1 5 5 5 0 Protein of unknown function (DUF3303) DUF2403 PF10290.9 OWF48472.1 - 0.055 13.9 0.4 0.099 13.1 0.4 1.4 1 0 0 1 1 1 0 Glycine-rich protein domain (DUF2403) Fringe PF02434.16 OWF48473.1 - 4.5e-97 324.4 0.3 5.5e-97 324.1 0.3 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF48473.1 - 4.2e-05 23.4 0.0 0.00013 21.8 0.0 1.8 1 1 1 2 2 2 1 Galactosyltransferase NPCC PF08058.11 OWF48473.1 - 0.098 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore complex component SNARE PF05739.19 OWF48474.1 - 0.024 14.6 0.1 0.068 13.2 0.1 1.8 1 0 0 1 1 1 0 SNARE domain Exonuc_VII_L PF02601.15 OWF48474.1 - 0.29 10.7 7.1 6.5 6.2 3.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit EzrA PF06160.12 OWF48474.1 - 0.82 7.8 8.3 0.066 11.4 2.9 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ALMT PF11744.8 OWF48474.1 - 1.2 7.9 6.0 1.6 7.4 5.8 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 OWF48474.1 - 2 7.7 5.1 3.3 7.0 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 OWF48474.1 - 2.5 8.7 7.7 0.58 10.7 2.7 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PH PF00169.29 OWF48475.1 - 1.3e-09 38.5 1.4 1.8e-09 38.0 0.3 1.9 2 0 0 2 2 2 1 PH domain RsbRD_N PF14361.6 OWF48475.1 - 0.14 12.9 0.3 0.36 11.5 0.3 1.8 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain RRN3 PF05327.11 OWF48475.1 - 0.66 8.4 4.7 9.8 4.6 1.9 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF465 PF04325.13 OWF48476.1 - 5.2e-06 26.4 40.3 1.5e+02 2.5 0.0 15.4 1 1 28 29 29 29 0 Protein of unknown function (DUF465) DUF2808 PF10989.8 OWF48476.1 - 1.7 8.6 58.8 23 5.0 8.7 5.7 1 1 3 4 4 4 0 Protein of unknown function (DUF2808) EGF PF00008.27 OWF48477.1 - 0.0009 19.5 3.5 0.002 18.4 3.5 1.6 1 0 0 1 1 1 1 EGF-like domain EphA2_TM PF14575.6 OWF48477.1 - 0.053 14.4 0.0 0.1 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain hEGF PF12661.7 OWF48477.1 - 0.054 14.1 1.2 0.13 12.9 1.2 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 OWF48477.1 - 0.076 13.4 4.5 0.25 11.7 4.5 1.9 1 1 0 1 1 1 0 EGF-like domain MFS_Mycoplasma PF07672.13 OWF48477.1 - 0.095 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter MAP17 PF15807.5 OWF48477.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Phage_Gp23 PF10669.9 OWF48477.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Herpes_gE PF02480.16 OWF48477.1 - 0.15 10.8 0.3 0.27 10.0 0.0 1.5 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ank_2 PF12796.7 OWF48478.1 - 1e-83 276.0 41.1 7.1e-17 61.8 1.2 9.8 4 3 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48478.1 - 4.7e-68 224.8 28.9 3.3e-11 43.5 0.0 11.5 5 3 7 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF48478.1 - 6e-63 201.3 29.6 0.00014 22.0 0.0 16.6 16 0 0 16 16 16 14 Ankyrin repeat Ank PF00023.30 OWF48478.1 - 1.1e-60 199.6 45.3 6.3e-05 23.2 0.0 16.7 16 1 1 17 17 17 12 Ankyrin repeat Ank_5 PF13857.6 OWF48478.1 - 8.7e-58 191.6 37.3 1.4e-09 38.0 0.2 13.7 3 3 11 14 14 14 13 Ankyrin repeats (many copies) PEGA PF08308.11 OWF48478.1 - 0.0057 16.5 0.0 1.4 8.9 0.0 3.3 3 0 0 3 3 3 1 PEGA domain VWA_3_C PF18571.1 OWF48478.1 - 0.12 12.2 1.2 83 3.2 0.0 3.6 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain NDUFB10 PF10249.9 OWF48479.1 - 4.5e-45 153.2 6.3 5.3e-45 153.0 6.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Ribosomal_L3 PF00297.22 OWF48480.1 - 9.2e-180 597.4 13.9 1e-179 597.2 13.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF22 PF01629.16 OWF48480.1 - 0.066 12.9 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 DUF1639 PF07797.14 OWF48480.1 - 0.082 12.9 5.8 2.3 8.3 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) Ank_2 PF12796.7 OWF48481.1 - 6.7e-18 65.1 0.2 7.2e-09 36.1 0.0 3.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48481.1 - 2.2e-15 56.8 0.2 6e-06 26.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF48481.1 - 1.8e-08 34.5 0.6 0.01 16.2 0.2 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF48481.1 - 2.4e-06 27.4 0.2 2.2 9.1 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 OWF48481.1 - 0.0011 19.3 0.0 1.5 9.4 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat 7tm_1 PF00001.21 OWF48482.1 - 3.5e-59 200.3 12.3 4.4e-59 199.9 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF48482.1 - 2.8e-15 56.6 14.0 4e-15 56.2 14.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF48482.1 - 4.1e-11 42.7 10.9 5.7e-11 42.3 10.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF48482.1 - 4.9e-09 36.3 14.0 2.3e-08 34.1 14.0 2.1 1 1 0 1 1 1 1 Olfactory receptor TAS2R PF05296.13 OWF48482.1 - 4.4e-05 22.7 2.7 4.4e-05 22.7 2.7 2.0 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) Git3 PF11710.8 OWF48482.1 - 0.0013 18.5 11.9 0.0024 17.7 11.9 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Serpentine_r_xa PF03383.15 OWF48482.1 - 0.31 11.0 6.5 0.095 12.7 2.8 2.0 2 1 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srt PF10321.9 OWF48482.1 - 0.67 8.9 13.2 1.5 7.7 13.2 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt Trypsin PF00089.26 OWF48483.1 - 9.2e-69 231.6 0.6 1.8e-68 230.7 0.6 1.5 1 0 0 1 1 1 1 Trypsin SRCR PF00530.18 OWF48483.1 - 1.5e-48 163.4 10.0 4.2e-27 94.6 1.3 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF48483.1 - 1.1e-11 45.1 4.4 1e-05 26.0 0.4 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 OWF48483.1 - 2.6e-10 40.3 8.6 2.6e-10 40.3 8.6 2.6 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Hepsin-SRCR PF09272.10 OWF48483.1 - 4.5e-05 23.9 7.7 0.0084 16.6 0.1 3.7 4 0 0 4 4 4 2 Hepsin, SRCR domain Trypsin_2 PF13365.6 OWF48483.1 - 7.9e-05 23.6 0.0 0.00028 21.8 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF48483.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) MFS_1 PF07690.16 OWF48484.1 - 2.1e-27 96.0 26.3 2.1e-27 96.0 26.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CrgA PF06781.12 OWF48485.1 - 0.0039 17.2 0.2 0.0039 17.2 0.2 1.5 2 0 0 2 2 2 1 Cell division protein CrgA DUF2207 PF09972.9 OWF48485.1 - 0.0043 15.9 0.1 0.0056 15.5 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 OWF48485.1 - 0.022 15.0 0.3 0.037 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2721 PF11026.8 OWF48485.1 - 0.027 14.4 0.2 0.038 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2157 PF09925.9 OWF48485.1 - 0.033 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Phage_holin_3_6 PF07332.11 OWF48485.1 - 0.078 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM174 PF15029.6 OWF48485.1 - 0.12 12.1 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 SdpI PF13630.6 OWF48486.1 - 0.044 13.9 1.1 0.044 13.9 1.1 1.5 2 0 0 2 2 2 0 SdpI/YhfL protein family TIG_plexin PF17960.1 OWF48486.1 - 0.14 12.2 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 TIG domain GPS2_interact PF15784.5 OWF48487.1 - 0.012 16.1 3.8 0.012 16.1 3.8 2.5 2 1 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain MCC-bdg_PDZ PF10506.9 OWF48487.1 - 0.014 15.4 0.9 0.014 15.4 0.9 2.5 2 2 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_TATA_bd PF12325.8 OWF48487.1 - 0.82 9.9 21.1 2.1 8.6 5.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 OWF48487.1 - 1 9.6 22.8 0.19 11.9 7.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec34 PF04136.15 OWF48487.1 - 1.3 8.9 12.1 0.12 12.2 3.5 2.3 2 0 0 2 2 2 0 Sec34-like family YabA PF06156.13 OWF48487.1 - 1.7 9.3 19.3 7.5 7.3 5.1 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 OWF48487.1 - 2.7 7.3 13.6 0.3 10.4 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 OWF48487.1 - 3 7.7 10.3 4.1 7.2 1.0 3.0 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.8 OWF48487.1 - 7.7 6.6 23.5 0.32 11.1 6.9 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 OWF48487.1 - 8.4 6.4 8.5 40 4.3 8.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RA PF00788.23 OWF48488.1 - 1.4e-13 51.3 0.0 2.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LIM PF00412.22 OWF48488.1 - 3.2e-13 49.7 4.4 5.3e-13 49.0 4.4 1.4 1 0 0 1 1 1 1 LIM domain Ras_bdg_2 PF14847.6 OWF48488.1 - 3.3e-05 24.2 0.0 9.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Nore1-SARAH PF16517.5 OWF48488.1 - 0.00044 20.1 0.3 0.0012 18.7 0.3 1.7 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zf_UBZ PF18439.1 OWF48488.1 - 0.025 14.2 3.9 2 8.1 1.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DCP1 PF06058.13 OWF48488.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family zf_C2H2_13 PF18508.1 OWF48488.1 - 0.17 11.5 2.5 0.89 9.2 0.1 2.4 2 0 0 2 2 2 0 Zinc finger domain zinc_ribbon_2 PF13240.6 OWF48488.1 - 0.22 11.3 3.4 10 6.0 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OWF48488.1 - 0.25 10.8 2.1 9.6 5.8 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain UQ_con PF00179.26 OWF48489.1 - 7.2e-42 142.4 0.0 8.2e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF48489.1 - 0.0021 18.3 0.0 0.0039 17.4 0.0 1.5 2 0 0 2 2 2 1 RWD domain MitoNEET_N PF10660.9 OWF48490.1 - 1.3e-20 73.1 2.5 1.8e-20 72.7 2.5 1.1 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 OWF48490.1 - 6.7e-11 42.2 0.2 1.2e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Transgly_assoc PF04226.13 OWF48492.1 - 0.0069 16.6 14.5 8.2 6.8 0.6 5.5 1 1 2 3 3 3 2 Transglycosylase associated protein Vut_1 PF02592.15 OWF48492.1 - 0.19 12.0 16.4 1.9 8.8 11.3 2.4 1 1 1 2 2 2 0 Putative vitamin uptake transporter Ntox10 PF15520.6 OWF48492.1 - 0.23 11.3 0.8 13 5.6 0.1 2.6 1 1 0 2 2 2 0 Novel toxin 10 MccV PF17508.2 OWF48492.1 - 0.69 10.5 12.6 13 6.4 1.0 3.8 1 1 2 3 3 3 0 Microcin V bacteriocin Baculo_p74 PF04583.12 OWF48492.1 - 4.8 6.6 14.2 2.1 7.8 5.3 2.2 1 1 1 2 2 2 0 Baculoviridae p74 conserved region AIG1 PF04548.16 OWF48493.1 - 7.2e-65 218.3 0.2 7.2e-65 218.3 0.2 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF48493.1 - 4e-07 30.1 0.5 1.2e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF48493.1 - 0.0038 16.8 0.4 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 OWF48493.1 - 0.0044 16.5 0.0 0.0044 16.5 0.0 2.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF48493.1 - 0.008 16.1 0.3 0.008 16.1 0.3 2.4 3 0 0 3 3 3 1 RsgA GTPase Hypoth_Ymh PF09509.10 OWF48493.1 - 0.032 14.1 2.9 0.046 13.6 1.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) AAA_7 PF12775.7 OWF48493.1 - 0.037 13.5 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 OWF48493.1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 OWF48493.1 - 0.22 12.0 0.1 0.22 12.0 0.1 2.6 2 1 0 2 2 1 0 ABC transporter DUF445 PF04286.12 OWF48493.1 - 0.29 10.9 6.9 1.5 8.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Peptidase_M24_C PF16188.5 OWF48493.1 - 0.47 10.5 2.4 6.7 6.9 0.1 2.7 2 1 0 2 2 2 0 C-terminal region of peptidase_M24 AAA_22 PF13401.6 OWF48493.1 - 0.66 10.3 4.2 0.43 10.9 0.6 2.6 1 1 1 2 2 2 0 AAA domain DUF4407 PF14362.6 OWF48493.1 - 2.7 7.2 7.0 5.2 6.3 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF87 PF01935.17 OWF48493.1 - 4.1 7.4 11.6 11 6.0 2.7 2.9 2 1 1 3 3 3 0 Helicase HerA, central domain OmpH PF03938.14 OWF48493.1 - 8.5 6.7 18.1 1.4 9.2 1.9 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) TetR_C_37 PF18665.1 OWF48493.1 - 10 6.8 8.0 7.7 7.2 0.3 3.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GST_C_3 PF14497.6 OWF48494.1 - 9.9e-17 61.0 0.0 1.5e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF48494.1 - 2e-08 34.5 0.0 4.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF48494.1 - 5.6e-08 32.9 0.0 8.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF48494.1 - 3.8e-06 27.2 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF48494.1 - 2.6e-05 24.4 0.1 5.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF48494.1 - 7.5e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF48494.1 - 0.0075 17.0 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF48494.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF48494.1 - 0.018 15.4 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Ifi-6-16 PF06140.13 OWF48495.1 - 6.5e-14 51.6 28.5 1e-13 51.0 28.5 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family TMEM154 PF15102.6 OWF48497.1 - 0.0037 17.2 2.3 0.0064 16.4 2.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 OWF48499.1 - 0.00012 22.3 3.9 0.00012 22.3 3.9 3.1 1 1 2 3 3 1 1 Wnt and FGF inhibitory regulator Cadherin_C_2 PF16492.5 OWF48499.1 - 0.001 19.7 0.6 0.0036 18.0 0.3 2.1 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal TMEM51 PF15345.6 OWF48499.1 - 0.0014 18.5 2.9 0.0035 17.2 2.9 1.7 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.6 OWF48499.1 - 0.002 19.0 0.1 0.005 17.7 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Sarcoglycan_2 PF05510.13 OWF48499.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Orthoreo_P10 PF07204.11 OWF48499.1 - 0.032 14.2 1.4 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 H-K_ATPase_N PF09040.11 OWF48499.1 - 0.033 14.6 0.0 2.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Gastric H+/K+-ATPase, N terminal domain Hamartin PF04388.12 OWF48499.1 - 0.066 11.9 23.1 0.082 11.6 23.1 1.1 1 0 0 1 1 1 0 Hamartin protein MIG-14_Wnt-bd PF06664.12 OWF48499.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion TrbL PF04610.14 OWF48499.1 - 0.19 11.4 1.5 0.35 10.6 1.5 1.3 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Sigma_reg_N PF13800.6 OWF48499.1 - 0.2 12.0 0.9 2.5 8.5 0.1 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ABA_WDS PF02496.16 OWF48499.1 - 0.98 9.9 8.2 0.072 13.6 1.9 2.3 2 1 1 3 3 3 0 ABA/WDS induced protein Aa_trans PF01490.18 OWF48500.1 - 4.8e-73 246.2 13.9 6.4e-73 245.8 13.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OWF48500.1 - 1.5e-08 34.1 13.6 3e-08 33.1 13.6 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 OWF48500.1 - 0.0012 17.8 12.2 0.017 14.0 5.6 2.7 2 1 0 2 2 2 2 Spore germination protein DUF1201 PF06716.11 OWF48500.1 - 1.2 9.2 4.7 22 5.2 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) COesterase PF00135.28 OWF48501.1 - 4e-154 514.3 0.0 4.6e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF48501.1 - 1.2e-08 35.1 0.0 9e-08 32.2 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold CENP-F_leu_zip PF10473.9 OWF48502.1 - 7.9e-05 22.7 51.9 0.00015 21.8 24.1 83.5 10 7 71 90 90 90 19 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kinocilin PF15033.6 OWF48502.1 - 0.14 11.8 0.1 0.75 9.5 0.1 2.4 1 0 0 1 1 1 0 Kinocilin protein 5_nucleotid PF05761.14 OWF48503.1 - 1.6e-60 205.4 0.3 2e-60 205.0 0.3 1.1 1 0 0 1 1 1 1 5' nucleotidase family DUF3891 PF13030.6 OWF48503.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) EF-hand_11 PF08976.11 OWF48504.1 - 1.5e-60 202.5 26.2 3.9e-10 40.5 0.0 13.2 13 0 0 13 13 13 9 EF-hand domain EF-hand_7 PF13499.6 OWF48504.1 - 9.2e-52 173.4 56.3 1.5e-05 25.3 0.1 13.6 12 1 1 13 13 13 12 EF-hand domain pair EF-hand_6 PF13405.6 OWF48504.1 - 5.5e-32 106.9 58.7 0.0022 17.8 0.4 18.5 19 0 0 19 19 19 9 EF-hand domain EF-hand_1 PF00036.32 OWF48504.1 - 4e-28 94.8 42.9 0.025 14.1 0.0 19.3 21 0 0 21 21 21 6 EF hand EF-hand_8 PF13833.6 OWF48504.1 - 4.3e-16 58.5 37.1 0.0003 20.6 0.0 13.2 14 1 1 15 15 14 5 EF-hand domain pair EF-hand_5 PF13202.6 OWF48504.1 - 2.3e-10 39.5 22.8 0.00028 20.2 0.0 8.3 10 0 0 10 10 10 4 EF hand EF-hand_9 PF14658.6 OWF48504.1 - 2.4e-09 37.4 0.3 0.22 11.9 0.0 7.8 9 0 0 9 9 8 1 EF-hand domain DUF5580 PF17743.1 OWF48504.1 - 9.2e-05 21.2 12.2 0.8 8.2 0.0 6.7 4 2 2 7 7 7 3 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 OWF48504.1 - 0.0016 18.6 1.7 14 6.0 0.1 4.7 5 0 0 5 5 4 0 Dockerin type I domain GPHH PF16905.5 OWF48504.1 - 0.0017 18.0 0.1 0.13 12.0 0.0 4.3 4 0 0 4 4 4 1 Voltage-dependent L-type calcium channel, IQ-associated DUF1456 PF07308.13 OWF48504.1 - 0.0038 17.5 3.0 0.13 12.6 0.0 5.0 6 0 0 6 6 4 1 Protein of unknown function (DUF1456) DUF2666 PF10869.8 OWF48504.1 - 0.0056 16.9 11.6 23 5.2 0.1 6.7 7 0 0 7 7 6 0 Protein of unknown function (DUF2666) TerB PF05099.13 OWF48504.1 - 0.015 15.2 0.6 3.3 7.7 0.0 4.4 5 0 0 5 5 5 0 Tellurite resistance protein TerB Herpes_BLRF2 PF05812.12 OWF48504.1 - 0.019 15.1 0.3 12 6.0 0.0 4.2 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein STAT1_TAZ2bind PF12162.8 OWF48504.1 - 0.024 14.2 1.4 0.087 12.4 0.2 2.7 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain DIL PF01843.19 OWF48504.1 - 0.1 12.9 0.2 1.6 9.0 0.0 2.9 2 0 0 2 2 2 0 DIL domain DUF3303 PF11746.8 OWF48504.1 - 0.14 12.4 0.1 8.5 6.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3303) EF-hand_14 PF17959.1 OWF48504.1 - 1.8 8.9 8.7 2e+02 2.4 0.0 6.3 6 0 0 6 6 6 0 EF-hand domain DUF1002 PF06207.11 OWF48504.1 - 2.6 7.5 6.5 1.1e+02 2.3 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1002) DUF5582 PF17819.1 OWF48505.1 - 0.0089 16.5 0.2 0.029 14.8 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5582) Exo_endo_phos PF03372.23 OWF48506.1 - 9.2e-14 51.5 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INPP5B_PH PF16776.5 OWF48506.1 - 1.7e-12 47.2 0.0 5.1e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain RhoGAP PF00620.27 OWF48507.1 - 1.4e-21 76.9 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain CTD PF12815.7 OWF48510.1 - 4.7e-05 23.9 0.0 0.032 14.8 0.0 2.4 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 LRR_4 PF12799.7 OWF48510.1 - 0.0019 18.6 23.7 4.2e+02 1.6 9.0 7.5 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) zf-RING_6 PF14835.6 OWF48510.1 - 0.0095 15.8 17.1 1.7 8.6 1.6 4.3 1 1 3 4 4 4 3 zf-RING of BARD1-type protein zf-RING_6 PF14835.6 OWF48511.1 - 1.3e-05 24.9 50.5 1.1 9.2 1.5 8.8 2 1 6 8 8 8 8 zf-RING of BARD1-type protein LRR_4 PF12799.7 OWF48511.1 - 0.002 18.5 32.2 18 5.9 0.3 9.5 2 2 3 5 5 5 1 Leucine Rich repeats (2 copies) Secretin PF00263.21 OWF48511.1 - 0.28 10.8 2.4 3.1 7.4 0.2 2.1 1 1 1 2 2 2 0 Bacterial type II and III secretion system protein Calici_MSP PF05752.11 OWF48511.1 - 4 7.2 25.1 60 3.4 0.0 7.9 2 1 4 6 6 6 0 Calicivirus minor structural protein TMEM154 PF15102.6 OWF48512.1 - 0.00078 19.4 6.4 0.0019 18.1 6.4 1.7 1 1 0 1 1 1 1 TMEM154 protein family Utp11 PF03998.13 OWF48513.1 - 1.1e-71 241.7 31.1 1.3e-71 241.5 31.1 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 OWF48513.1 - 0.052 12.9 0.4 0.052 12.9 0.4 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Ribosomal_S9 PF00380.19 OWF48514.1 - 4.5e-32 111.1 0.0 6.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ig_3 PF13927.6 OWF48515.1 - 1.4e-10 41.6 1.3 1.4e-06 28.8 0.1 3.5 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 OWF48515.1 - 5e-06 26.5 0.5 0.016 15.2 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin I-set domain fn3 PF00041.21 OWF48515.1 - 0.00015 22.0 0.1 0.00054 20.3 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.6 OWF48515.1 - 0.00057 20.2 2.1 0.0024 18.2 0.1 2.8 3 1 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 OWF48515.1 - 0.00083 19.5 1.1 0.0015 18.7 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain PRP38 PF03371.15 OWF48516.1 - 4.2e-56 189.6 0.0 5.4e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF3244 PF11589.8 OWF48517.1 - 0.45 10.6 49.2 9 6.5 2.5 7.9 1 1 5 7 7 7 0 Domain of unknown function (DUF3244) RabGAP-TBC PF00566.18 OWF48518.1 - 2.7e-06 27.2 0.3 6.4e-06 26.0 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SKA1 PF07160.12 OWF48518.1 - 9.1 6.0 8.1 5.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Fibrinogen_C PF00147.18 OWF48519.1 - 1.8e-64 217.6 9.5 3.8e-64 216.5 9.5 1.6 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Laminin_II PF06009.12 OWF48519.1 - 0.00027 20.9 2.0 0.00027 20.9 2.0 5.5 4 3 1 5 5 5 1 Laminin Domain II MADF_DNA_bdg PF10545.9 OWF48519.1 - 1.8 8.9 9.7 6.3 7.2 0.1 3.8 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TcdB_N PF12918.7 OWF48519.1 - 4.7 7.6 8.5 6.5 7.1 0.0 3.8 3 1 1 4 4 4 0 TcdB toxin N-terminal helical domain DUF948 PF06103.11 OWF48519.1 - 7.5 6.9 22.2 44 4.4 1.0 6.1 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) RabGAP-TBC PF00566.18 OWF48520.1 - 2.5e-35 122.1 0.9 6e-35 120.9 0.9 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 OWF48520.1 - 4.2e-09 36.9 0.3 2e-08 34.7 0.1 2.1 2 0 0 2 2 2 1 PH domain Adhesin_P1_N PF18652.1 OWF48520.1 - 0.033 14.2 0.1 6 7.0 0.1 2.7 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain TMF_TATA_bd PF12325.8 OWF48520.1 - 0.15 12.3 9.7 0.26 11.5 3.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Angiomotin_C PF12240.8 OWF48520.1 - 4.8 6.7 11.1 1.7 8.1 7.0 2.0 1 1 1 2 2 2 0 Angiomotin C terminal PIP49_C PF12260.8 OWF48521.1 - 2.8e-35 121.7 0.3 3.9e-35 121.2 0.3 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 OWF48521.1 - 5.8e-08 32.8 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 N-term cysteine-rich ER, FAM69 NT-C2 PF10358.9 OWF48522.1 - 7.3e-28 97.1 0.1 7.3e-28 97.1 0.1 1.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins TPR_16 PF13432.6 OWF48523.1 - 0.00019 22.0 0.0 0.00025 21.6 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF48523.1 - 0.00052 20.5 0.0 0.00086 19.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Pentapeptide_4 PF13599.6 OWF48523.1 - 0.0015 18.6 0.8 0.15 12.2 0.2 3.0 2 1 2 4 4 4 2 Pentapeptide repeats (9 copies) TPR_14 PF13428.6 OWF48523.1 - 0.004 17.9 0.0 0.026 15.3 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Ig_2 PF13895.6 OWF48523.1 - 0.0098 16.2 3.6 6.8 7.1 0.1 3.5 1 1 2 3 3 3 1 Immunoglobulin domain Sulf_coat_C PF12193.8 OWF48523.1 - 0.013 15.5 1.2 10 6.2 0.0 3.7 1 1 0 3 3 3 0 Sulfolobus virus coat protein C terminal ANAPC3 PF12895.7 OWF48523.1 - 0.043 14.0 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4376 PF14301.6 OWF48523.1 - 0.13 12.6 0.1 12 6.4 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4376) DinI PF06183.13 OWF48523.1 - 0.15 12.4 0.1 0.96 9.8 0.1 2.3 1 1 1 2 2 2 0 DinI-like family UPF0240 PF06784.11 OWF48523.1 - 0.3 11.1 5.8 0.75 9.8 5.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) TPR_14 PF13428.6 OWF48524.1 - 0.0028 18.3 2.4 0.73 10.8 0.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF48524.1 - 0.022 14.9 0.4 0.53 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3549 PF12069.8 OWF48524.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) TPR_5 PF12688.7 OWF48524.1 - 0.028 14.7 0.0 1.4 9.2 0.0 2.9 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_19 PF14559.6 OWF48524.1 - 0.03 14.8 2.2 0.36 11.4 0.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF48524.1 - 0.072 13.2 2.4 5.7 7.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OWF48524.1 - 0.075 13.5 0.1 19 5.7 0.1 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_11 PF13414.6 OWF48524.1 - 0.076 12.7 0.4 16 5.3 0.0 2.8 3 0 0 3 3 3 0 TPR repeat Tfb2 PF03849.14 OWF48525.1 - 9.6e-134 445.8 0.0 1.1e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OWF48525.1 - 4.3e-27 94.3 2.1 5.1e-27 94.1 0.7 1.9 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OWF48525.1 - 0.0023 18.0 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HATPase_c_3 PF13589.6 OWF48527.1 - 0.00038 20.3 0.3 0.58 10.0 0.5 3.6 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OWF48528.1 - 0.025 14.4 0.2 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SSF PF00474.17 OWF48529.1 - 9.7e-35 120.2 18.6 1.4e-34 119.7 18.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF485 PF04341.12 OWF48529.1 - 0.041 13.8 0.2 0.34 10.9 0.2 2.6 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF5316 PF17247.2 OWF48529.1 - 6.7 6.8 7.5 3.2 7.8 0.0 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5316) Filament PF00038.21 OWF48530.1 - 1.4e-66 225.3 61.5 5.8e-66 223.2 61.5 1.8 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 OWF48530.1 - 7.5e-18 64.9 0.1 1.8e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 Lamin Tail Domain Pih1_fungal_CS PF18482.1 OWF48530.1 - 0.59 10.7 4.5 1.9 9.1 0.4 2.8 2 0 0 2 2 2 0 Fungal Pih1 CS domain FlaC_arch PF05377.11 OWF48530.1 - 2.3 8.7 12.4 14 6.2 0.3 5.3 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) SNCAIP_SNCA_bd PF16700.5 OWF48530.1 - 6.2 6.6 8.2 0.44 10.3 1.1 2.8 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain Abhydrolase_1 PF00561.20 OWF48531.1 - 1e-07 31.9 0.3 1.6e-07 31.3 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF48531.1 - 7.6e-05 23.4 0.0 9.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF48531.1 - 0.0027 17.0 0.0 0.0061 15.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 OWF48531.1 - 0.021 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family GFO_IDH_MocA PF01408.22 OWF48532.1 - 1e-20 74.8 0.0 1.7e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OWF48532.1 - 5.5e-08 32.8 0.1 1.6e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1091 PF06477.13 OWF48532.1 - 0.078 13.5 0.0 3.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) Cys_Knot_tox PF17486.2 OWF48532.1 - 0.15 12.3 2.8 0.7 10.2 0.1 2.8 3 0 0 3 3 3 0 Cystine knot toxins DUF5305 PF17231.2 OWF48534.1 - 0.012 15.0 0.2 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) UDG PF03167.19 OWF48535.1 - 8.2e-24 84.4 0.0 1.9e-23 83.2 0.0 1.5 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily C_Hendra PF16821.5 OWF48535.1 - 0.13 12.1 1.4 0.22 11.4 1.4 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses RIIa PF02197.17 OWF48535.1 - 0.14 11.8 0.2 0.41 10.4 0.2 1.7 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit UDG PF03167.19 OWF48536.1 - 3.8e-22 78.9 0.0 8.9e-22 77.7 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily COesterase PF00135.28 OWF48537.1 - 3.5e-13 49.3 0.0 3.9e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 OWF48538.1 - 3.6e-11 42.6 0.0 4.2e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family RBFA PF02033.18 OWF48539.1 - 2 8.9 65.3 1.8e+04 -17.7 27.6 11.7 1 1 1 2 2 2 0 Ribosome-binding factor A MucB_RseB PF03888.14 OWF48540.1 - 0.0011 18.6 8.1 1.9 8.0 0.2 4.8 3 1 2 5 5 5 4 MucB/RseB N-terminal domain I-set PF07679.16 OWF48542.1 - 0.0003 20.8 0.0 0.0003 20.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF48542.1 - 0.00083 19.5 0.2 0.0011 19.1 0.2 1.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 OWF48542.1 - 0.0055 17.3 1.5 0.01 16.5 1.5 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF48542.1 - 0.0063 16.8 1.8 0.0099 16.2 1.8 1.4 1 1 0 1 1 1 1 Immunoglobulin domain PHD PF00628.29 OWF48543.1 - 0.00017 21.4 5.2 0.00046 20.0 5.2 1.8 1 0 0 1 1 1 1 PHD-finger BUD22 PF09073.10 OWF48543.1 - 1.7 7.9 7.1 3.1 7.1 7.1 1.3 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 OWF48543.1 - 3.7 7.4 11.8 6 6.7 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_C PF00271.31 OWF48544.1 - 6.4e-14 52.2 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF48544.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4744 PF15918.5 OWF48545.1 - 0.0003 21.5 24.7 0.028 15.2 0.8 4.0 1 1 3 4 4 4 4 Domain of unknown function (DUF4744) NLE PF08154.12 OWF48545.1 - 7.6 7.1 12.8 1.3e+02 3.2 0.8 5.8 2 2 2 4 4 4 0 NLE (NUC135) domain Mesothelin PF06060.12 OWF48546.1 - 0.05 11.8 0.0 0.056 11.6 0.0 1.0 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Cu2_monoox_C PF03712.15 OWF48547.1 - 2.2e-25 89.0 1.0 6e-25 87.6 1.0 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF48547.1 - 3.4e-25 88.8 0.3 3.4e-25 88.8 0.3 2.9 3 0 0 3 3 3 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Fibrillin_U_N PF18193.1 OWF48548.1 - 0.00047 20.2 13.5 0.29 11.3 1.0 3.1 3 0 0 3 3 3 3 Fibrillin 1 unique N-terminal domain PPR_long PF17177.4 OWF48548.1 - 0.012 15.0 0.5 4.1 6.7 0.1 2.9 1 1 2 3 3 3 0 Pentacotripeptide-repeat region of PRORP DUF1475 PF07343.11 OWF48548.1 - 0.027 14.3 2.1 0.69 9.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1475) Defensin_int PF17858.1 OWF48548.1 - 0.042 13.8 7.5 5.1 7.2 0.3 3.2 3 0 0 3 3 3 0 Platypus intermediate defensin-like peptide HTH_ABP1_N PF18107.1 OWF48548.1 - 0.078 12.7 0.7 23 4.8 0.1 3.0 3 0 0 3 3 3 0 Fission yeast centromere protein N-terminal domain PaRep2b PF07775.11 OWF48548.1 - 0.25 9.8 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 PaRep2b protein PLAC PF08686.11 OWF48548.1 - 5.1 7.9 10.3 26 5.7 0.4 3.2 3 0 0 3 3 3 0 PLAC (protease and lacunin) domain GTP_EFTU_D3 PF03143.17 OWF48549.1 - 7.8e-35 119.6 0.0 1.7e-34 118.5 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OWF48549.1 - 1.9e-05 25.0 0.3 5.3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 OWF48550.1 - 7e-22 77.9 0.0 8.8e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OWF48550.1 - 0.0015 18.3 0.2 0.83 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OWF48550.1 - 0.0069 16.5 1.2 0.04 14.0 1.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF48550.1 - 0.027 14.8 0.4 0.07 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 OWF48550.1 - 0.032 13.5 0.4 0.66 9.3 0.1 2.7 3 0 0 3 3 3 0 AIG1 family G-alpha PF00503.20 OWF48550.1 - 0.035 13.2 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 OWF48550.1 - 0.039 14.5 0.4 2.7 8.5 0.7 2.2 1 1 1 2 2 2 0 ABC transporter POTRA PF07244.15 OWF48550.1 - 0.052 14.1 0.1 0.48 11.0 0.0 2.5 2 1 1 3 3 3 0 Surface antigen variable number repeat AIP3 PF03915.13 OWF48551.1 - 8.4e-27 94.3 11.2 3.5e-17 62.6 5.3 2.7 3 0 0 3 3 3 2 Actin interacting protein 3 ARL6IP6 PF15062.6 OWF48554.1 - 0.2 11.8 1.0 0.3 11.2 0.5 1.6 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix P34-Arc PF04045.14 OWF48555.1 - 3e-102 341.4 1.1 3.6e-102 341.1 1.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 OWF48555.1 - 0.11 12.1 0.1 0.74 9.4 0.1 2.1 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Citrate_synt PF00285.21 OWF48556.1 - 5e-106 354.8 0.0 6.1e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Methyltransf_21 PF05050.12 OWF48557.1 - 2.2e-11 44.1 0.1 4e-11 43.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase FkbM domain ThiS PF02597.20 OWF48557.1 - 0.0052 17.4 0.0 0.067 13.8 0.0 2.3 2 0 0 2 2 2 1 ThiS family Cation_ATPase PF13246.6 OWF48557.1 - 0.006 16.6 0.0 8.4 6.6 0.0 3.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Fuseless PF15993.5 OWF48557.1 - 0.045 12.9 0.2 0.062 12.5 0.2 1.1 1 0 0 1 1 1 0 Fuseless ODV-E18 PF10717.9 OWF48557.1 - 0.15 11.9 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 C1q PF00386.21 OWF48558.1 - 9.3e-27 93.7 2.2 1.1e-26 93.6 0.7 1.8 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF48558.1 - 0.0022 17.9 0.3 0.0041 17.0 0.3 1.4 1 0 0 1 1 1 1 BclA C-terminal domain GAS PF13851.6 OWF48558.1 - 0.11 11.9 14.2 0.34 10.2 14.6 1.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 OWF48558.1 - 0.44 10.4 5.3 0.74 9.6 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 OWF48558.1 - 0.51 10.4 9.7 0.28 11.2 4.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 OWF48558.1 - 0.79 9.7 17.7 11 6.0 0.3 5.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Atg14 PF10186.9 OWF48558.1 - 1.2 8.2 8.9 1.5 7.8 8.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PspB PF06667.12 OWF48558.1 - 2.3 8.3 11.2 1.6 8.8 2.1 3.4 3 0 0 3 3 3 0 Phage shock protein B DUF5595 PF18077.1 OWF48558.1 - 3.2 7.9 8.3 7.9 6.6 3.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) TRAF_BIRC3_bd PF16673.5 OWF48558.1 - 4.6 7.1 9.0 5.7 6.8 0.5 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain C1q PF00386.21 OWF48559.1 - 7.6e-26 90.8 2.4 1.1e-25 90.3 0.2 2.2 2 0 0 2 2 2 1 C1q domain Atg14 PF10186.9 OWF48559.1 - 0.12 11.5 13.6 0.15 11.1 13.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF465 PF04325.13 OWF48559.1 - 0.46 10.6 25.2 0.84 9.7 3.1 4.9 3 2 2 5 5 5 0 Protein of unknown function (DUF465) TRAF_BIRC3_bd PF16673.5 OWF48559.1 - 0.56 10.0 13.9 3.3 7.6 2.8 3.7 1 1 3 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain V_ATPase_I PF01496.19 OWF48559.1 - 3.2 5.6 9.0 3.9 5.3 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BBP1_C PF15272.6 OWF48559.1 - 5.5 6.8 27.3 2.7 7.8 19.9 2.4 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Cortex-I_coil PF09304.10 OWF48559.1 - 6.9 6.9 17.7 4.1 7.7 13.4 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil C1q PF00386.21 OWF48560.1 - 2.9e-25 88.9 1.6 2.9e-25 88.9 1.6 1.6 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF48560.1 - 0.15 12.0 0.4 0.3 11.0 0.4 1.5 1 0 0 1 1 1 0 BclA C-terminal domain CtIP_N PF10482.9 OWF48560.1 - 0.27 11.3 9.2 1 9.4 1.2 2.6 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Mg_chelatase_C PF13335.6 OWF48560.1 - 0.44 11.2 3.8 61 4.4 0.2 3.8 2 2 2 4 4 4 0 Magnesium chelatase, subunit ChlI C-terminal Macoilin PF09726.9 OWF48560.1 - 3.5 6.1 10.5 5.2 5.5 10.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF465 PF04325.13 OWF48560.1 - 5.8 7.0 11.8 9.7 6.3 2.4 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF465) DUF5595 PF18077.1 OWF48560.1 - 6.1 7.0 9.2 6.5 6.9 1.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) Pox_A_type_inc PF04508.12 OWF48560.1 - 8.5 6.4 9.2 7.7 6.6 0.4 3.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Med24_N PF11277.8 OWF48561.1 - 2.2e-279 929.8 12.6 2.7e-279 929.5 12.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal 7tm_1 PF00001.21 OWF48562.1 - 2e-11 43.8 12.0 2.6e-11 43.4 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 OWF48562.1 - 0.0023 17.1 12.8 0.0037 16.4 12.8 1.4 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) CcmF_C PF16327.5 OWF48562.1 - 0.69 9.1 5.7 0.11 11.8 1.8 1.6 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal His_Phos_2 PF00328.22 OWF48563.1 - 2.9e-30 105.9 0.3 1.3e-16 61.0 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) RNA_pol_Rpb2_6 PF00562.28 OWF48565.1 - 1.2e-102 343.9 0.0 2.2e-79 267.3 0.0 2.6 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 OWF48565.1 - 3.4e-29 100.8 0.1 6.6e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 OWF48565.1 - 9.3e-22 77.2 0.1 2.6e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 OWF48565.1 - 3.9e-20 71.6 0.0 8.2e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain zf-Sec23_Sec24 PF04810.15 OWF48565.1 - 0.021 14.9 3.1 0.17 11.9 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger FYVE_2 PF02318.16 OWF48565.1 - 0.34 11.1 1.3 1.6 9.0 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger EzrA PF06160.12 OWF48566.1 - 0.1 10.8 0.5 0.13 10.4 0.5 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fringe PF02434.16 OWF48567.1 - 2.5e-11 43.5 0.6 2.3e-10 40.3 0.6 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF48567.1 - 4.3e-06 26.7 0.5 0.01 15.7 0.1 2.4 1 1 1 2 2 2 2 Galactosyltransferase Glyco_trans_2_3 PF13632.6 OWF48567.1 - 0.048 13.6 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_25 PF01755.17 OWF48567.1 - 0.055 13.3 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Rab5ip PF07019.12 OWF48567.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Fringe PF02434.16 OWF48568.1 - 4.9e-10 39.3 0.6 3.2e-09 36.6 0.6 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF48568.1 - 2.3e-05 24.3 0.2 0.042 13.7 0.1 2.5 1 1 1 2 2 2 2 Galactosyltransferase Glyco_transf_25 PF01755.17 OWF48568.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Thiolase_N PF00108.23 OWF48569.1 - 7e-76 255.0 0.2 1e-75 254.5 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OWF48569.1 - 2.5e-45 153.1 0.3 5.8e-45 151.9 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 OWF48569.1 - 0.00012 22.2 0.0 0.00045 20.3 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 OWF48569.1 - 0.00037 20.1 0.5 0.0045 16.6 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Raf1_HTH PF18579.1 OWF48569.1 - 0.12 12.1 0.1 2.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain p450 PF00067.22 OWF48571.1 - 5.5e-26 91.3 0.0 6.4e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF48572.1 - 1e-119 400.4 0.0 1.1e-119 400.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF48573.1 - 9.6e-14 51.0 0.0 1.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DIM PF08194.12 OWF48573.1 - 1.6 9.0 5.9 1.9 8.8 0.5 2.3 2 0 0 2 2 2 0 DIM protein YjcZ_2 PF09680.10 OWF48573.1 - 7.8 6.2 11.7 0.35 10.6 5.5 2.0 2 0 0 2 2 2 0 Family of unknown function CotH PF08757.11 OWF48574.1 - 0.0026 17.3 1.9 0.69 9.4 0.2 2.6 1 1 0 2 2 2 2 CotH kinase protein Lip_prot_lig_C PF10437.9 OWF48574.1 - 0.049 13.6 1.0 26 4.9 0.1 3.8 1 1 3 5 5 5 0 Bacterial lipoate protein ligase C-terminus Cortex-I_coil PF09304.10 OWF48574.1 - 0.085 13.1 2.7 0.13 12.5 1.2 2.1 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF1967 PF09269.11 OWF48574.1 - 0.087 12.8 11.5 3.7 7.6 0.2 5.4 1 1 6 7 7 7 0 Domain of unknown function (DUF1967) DUF445 PF04286.12 OWF48574.1 - 9.2 6.0 25.0 31 4.2 1.5 4.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF1133 PF06576.11 OWF48574.1 - 9.3 5.6 11.6 1.3 8.4 1.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1133) LRR_8 PF13855.6 OWF48575.1 - 1.5e-99 325.7 117.1 2.9e-15 55.8 3.2 10.5 3 2 8 11 11 11 11 Leucine rich repeat LRR_5 PF13306.6 OWF48575.1 - 7.6e-43 145.5 30.4 7e-13 48.7 3.3 5.9 2 2 4 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF48575.1 - 5.4e-34 115.7 79.3 0.00024 21.4 0.8 12.1 6 2 6 13 13 13 12 Leucine Rich repeats (2 copies) 7tm_1 PF00001.21 OWF48575.1 - 7.2e-26 91.1 11.8 1.1e-25 90.5 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_9 PF14580.6 OWF48575.1 - 3.4e-13 49.5 34.1 0.0025 17.3 0.9 6.4 2 2 4 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 OWF48575.1 - 3.6e-10 39.0 58.2 0.24 12.1 0.6 17.2 17 0 0 17 17 17 3 Leucine Rich Repeat NosD PF05048.13 OWF48575.1 - 0.00015 21.1 16.0 0.0008 18.7 3.0 2.7 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) 7TM_GPCR_Srv PF10323.9 OWF48575.1 - 0.0017 17.8 8.6 0.0017 17.8 8.6 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv LRR_6 PF13516.6 OWF48575.1 - 0.0022 17.9 40.6 6.5 7.1 0.1 12.1 14 0 0 14 14 12 1 Leucine Rich repeat DUF4457 PF14652.6 OWF48575.1 - 0.0089 15.3 0.9 0.96 8.6 0.0 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4457) 7TM_GPCR_Srw PF10324.9 OWF48575.1 - 0.76 9.0 12.4 11 5.1 12.4 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Beta_helix PF13229.6 OWF48575.1 - 2.8 7.8 14.0 1.9 8.3 5.0 3.3 1 1 2 3 3 3 0 Right handed beta helix region MFS_1 PF07690.16 OWF48577.1 - 1.2e-09 37.6 23.3 8e-06 25.0 12.9 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_M19 PF01244.21 OWF48578.1 - 4.3e-106 354.7 0.0 6.6e-106 354.1 0.0 1.3 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Dus PF01207.17 OWF48579.1 - 2.3e-58 197.8 0.0 5.9e-58 196.4 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 OWF48579.1 - 1.2e-07 31.3 8.9 3.3e-06 26.8 0.3 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 OWF48579.1 - 1.6e-07 31.0 9.9 0.0015 18.3 2.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF48579.1 - 5e-05 23.2 13.9 0.021 14.9 1.5 2.7 2 0 0 2 2 2 2 Zinc finger domain PEP_mutase PF13714.6 OWF48579.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase RNA_pol_Rbc25 PF08292.12 OWF48579.1 - 1.3 9.2 5.8 0.4 10.9 1.1 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 zf-CCCH_2 PF14608.6 OWF48579.1 - 4.2 8.0 9.4 2.3 8.8 1.0 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PAN_1 PF00024.26 OWF48580.1 - 2.7e-08 33.6 1.8 2.9e-08 33.6 1.8 1.1 1 0 0 1 1 1 1 PAN domain DUF3892 PF13031.6 OWF48581.1 - 0.00084 19.9 0.2 43 4.8 0.1 5.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3892) DUF1107 PF06526.12 OWF48581.1 - 0.035 14.0 2.7 4 7.4 0.0 5.1 4 2 3 7 7 7 0 Protein of unknown function (DUF1107) DUF4221 PF13970.6 OWF48581.1 - 0.95 9.0 5.3 5.8 6.4 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) MFS_1 PF07690.16 OWF48582.1 - 2.2e-19 69.6 31.1 2.7e-19 69.3 21.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Band_7 PF01145.25 OWF48583.1 - 4.6e-29 101.7 1.4 6.6e-29 101.2 1.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OWF48583.1 - 0.0044 16.8 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Tweety PF04906.13 OWF48583.1 - 0.041 12.6 0.4 0.76 8.4 0.0 2.1 2 0 0 2 2 2 0 Tweety FAM60A PF15396.6 OWF48583.1 - 0.13 12.3 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Band_7 PF01145.25 OWF48584.1 - 5e-30 104.8 0.1 6.7e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OWF48584.1 - 0.0016 18.2 0.1 0.0023 17.7 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 OWF48584.1 - 0.054 13.9 0.9 0.13 12.7 0.4 1.9 1 1 0 1 1 1 0 Phage protein Gp68 PGDYG PF14083.6 OWF48584.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 PGDYG protein Cnn_1N PF07989.11 OWF48585.1 - 1.2e-21 76.7 5.2 1.2e-21 76.7 5.2 24.2 15 6 12 29 29 29 2 Centrosomin N-terminal motif 1 Lzipper-MIP1 PF14389.6 OWF48585.1 - 0.00035 20.8 4.2 0.00035 20.8 4.2 19.5 17 6 4 22 22 22 4 Leucine-zipper of ternary complex factor MIP1 DUF4634 PF15465.6 OWF48585.1 - 5 7.4 6.1 78 3.6 0.1 5.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4634) PIP5K PF01504.18 OWF48586.1 - 2.5e-57 194.2 0.2 4.2e-57 193.5 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SGL PF08450.12 OWF48589.1 - 3.6e-07 30.0 0.7 0.046 13.3 0.0 3.5 2 1 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 OWF48589.1 - 9.8e-06 25.6 2.1 2.5e-05 24.3 2.1 1.8 1 0 0 1 1 1 1 B-box zinc finger NHL PF01436.21 OWF48589.1 - 2.6e-05 24.0 2.5 0.0023 17.9 0.3 3.8 4 0 0 4 4 4 1 NHL repeat DUF4515 PF14988.6 OWF48589.1 - 0.0012 18.8 4.8 0.0012 18.8 4.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4515) Atg14 PF10186.9 OWF48589.1 - 0.0072 15.4 9.6 0.011 14.8 9.6 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Reg_prop PF07494.11 OWF48589.1 - 0.0097 16.0 0.7 73 4.1 0.0 4.8 4 1 1 5 5 4 0 Two component regulator propeller zf-UBR PF02207.20 OWF48589.1 - 0.028 14.6 1.9 0.088 13.0 1.9 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Fib_alpha PF08702.10 OWF48589.1 - 0.03 14.5 5.8 0.044 14.0 5.0 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Apolipoprotein PF01442.18 OWF48589.1 - 0.032 14.1 6.9 0.05 13.5 6.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain LMBR1 PF04791.16 OWF48589.1 - 0.069 12.1 1.8 0.087 11.7 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 OWF48589.1 - 0.086 11.7 1.6 0.12 11.1 1.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Prominin PF05478.11 OWF48589.1 - 0.088 10.8 9.1 0.12 10.3 9.1 1.1 1 0 0 1 1 1 0 Prominin DUF2203 PF09969.9 OWF48589.1 - 0.089 13.5 3.9 5.7 7.7 1.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) 7TMR-HDED PF07697.11 OWF48589.1 - 0.12 12.5 2.6 0.18 11.9 2.6 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Exonuc_VII_L PF02601.15 OWF48589.1 - 0.28 10.7 5.8 0.43 10.1 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BshC PF10079.9 OWF48589.1 - 0.3 9.8 6.2 0.41 9.3 6.2 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC ApoLp-III PF07464.11 OWF48589.1 - 0.32 11.1 4.3 0.67 10.0 4.1 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DLP_helical PF18709.1 OWF48589.1 - 0.53 9.4 7.0 3 6.9 7.0 1.9 1 1 0 1 1 1 0 Dynamin-like helical domain DUF883 PF05957.13 OWF48589.1 - 0.55 10.9 5.8 7.6 7.2 5.8 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 OWF48589.1 - 4.3 7.9 6.6 3.8 8.1 3.2 2.2 2 0 0 2 2 2 0 YtxH-like protein Phage_Mu_Gam PF07352.12 OWF48589.1 - 5.3 6.9 8.6 0.48 10.3 1.9 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein FapA PF03961.13 OWF48589.1 - 8.8 4.8 8.3 15 4.0 7.6 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A zf-B_box PF00643.24 OWF48590.1 - 1.4e-07 31.5 2.2 2.6e-07 30.7 2.2 1.5 1 0 0 1 1 1 1 B-box zinc finger SGL PF08450.12 OWF48590.1 - 0.00073 19.2 0.1 0.43 10.1 0.0 2.9 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF48590.1 - 0.0021 18.1 0.3 14 6.4 0.0 4.5 4 0 0 4 4 3 1 Two component regulator propeller DUF507 PF04368.13 OWF48590.1 - 0.0065 16.4 8.2 0.0071 16.3 6.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF507) Clathrin_lg_ch PF01086.17 OWF48590.1 - 0.0069 16.5 0.4 0.011 15.8 0.4 1.2 1 0 0 1 1 1 1 Clathrin light chain Baculo_PEP_C PF04513.12 OWF48590.1 - 0.014 15.4 1.6 0.026 14.6 1.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NHL PF01436.21 OWF48590.1 - 0.045 13.8 0.5 1.3 9.2 0.2 3.2 3 0 0 3 3 3 0 NHL repeat zf-UBR PF02207.20 OWF48590.1 - 0.093 12.9 3.7 0.075 13.2 1.6 1.9 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) HAUS5 PF14817.6 OWF48590.1 - 0.17 10.6 2.3 0.24 10.1 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 COG2 PF06148.11 OWF48590.1 - 0.22 11.6 4.4 1.2 9.3 4.4 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Muted PF14942.6 OWF48590.1 - 0.27 11.6 5.5 0.34 11.3 4.8 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein V_ATPase_I PF01496.19 OWF48590.1 - 1.4 6.7 3.6 2 6.2 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2475 PF10629.9 OWF48591.1 - 3.3e-27 94.5 8.2 7.4e-11 42.1 0.1 4.4 4 0 0 4 4 4 4 Protein of unknown function (DUF2475) zf-H2C2_2 PF13465.6 OWF48592.1 - 2.3e-09 37.3 57.0 0.0038 17.6 3.3 9.1 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.26 OWF48592.1 - 5e-07 29.8 64.7 0.018 15.5 0.2 10.0 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF48592.1 - 6.1e-06 26.6 64.9 0.097 13.6 0.2 10.5 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF48592.1 - 0.0044 16.7 2.3 0.0044 16.7 2.3 5.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-met PF12874.7 OWF48592.1 - 0.2 12.1 0.0 0.2 12.1 0.0 8.5 10 0 0 10 10 10 0 Zinc-finger of C2H2 type RNA_pol_Rpb1_4 PF05000.17 OWF48593.1 - 0.016 15.2 0.0 0.016 15.2 0.0 2.3 2 1 1 3 3 3 0 RNA polymerase Rpb1, domain 4 Suf PF05843.14 OWF48593.1 - 0.13 12.2 1.4 0.22 11.5 1.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TRAP_alpha PF03896.16 OWF48593.1 - 0.69 9.1 4.1 12 5.0 0.7 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4834 PF16118.5 OWF48593.1 - 4.7 8.2 0.0 4.7 8.2 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) LIP1 PF15904.5 OWF48594.1 - 4.1e-13 49.5 1.5 7.5e-12 45.4 1.5 2.8 1 1 0 1 1 1 1 LKB1 serine/threonine kinase interacting protein 1 LRR_8 PF13855.6 OWF48594.1 - 6.4e-08 32.2 19.6 0.0021 17.8 0.2 5.0 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OWF48594.1 - 0.0015 18.9 28.2 0.12 12.8 4.2 6.7 4 1 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF48594.1 - 0.0037 16.8 2.1 0.067 12.7 0.9 2.5 1 1 1 2 2 2 2 Leucine-rich repeat SCP2_2 PF13530.6 OWF48594.1 - 0.071 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Sterol carrier protein domain Sulfotransfer_2 PF03567.14 OWF48595.1 - 6e-27 95.2 0.4 1.5e-24 87.3 0.4 2.1 1 1 0 1 1 1 1 Sulfotransferase family Ribosomal_L27e PF01777.18 OWF48595.1 - 0.0022 18.3 0.1 2.9 8.3 0.1 3.1 3 0 0 3 3 3 2 Ribosomal L27e protein family PKD_3 PF16820.5 OWF48595.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 PKD-like domain EF-hand_7 PF13499.6 OWF48596.1 - 3.8e-08 33.7 0.2 5.6e-08 33.1 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF48596.1 - 5.2e-07 29.1 0.5 0.043 13.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF48596.1 - 5.6e-07 28.7 0.8 0.037 13.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OWF48596.1 - 1.1e-06 27.9 0.2 0.032 13.7 0.0 2.4 2 0 0 2 2 2 2 EF hand Msg2_C PF12373.8 OWF48596.1 - 0.022 14.2 0.1 0.047 13.1 0.1 1.6 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal SPARC_Ca_bdg PF10591.9 OWF48596.1 - 0.022 15.1 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 OWF48596.1 - 0.066 13.1 1.2 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 OWF48598.1 - 1.8e-07 31.5 0.5 2.7e-07 30.9 0.5 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF48598.1 - 1.5e-06 27.3 1.9 0.012 15.2 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF48598.1 - 1.6e-06 27.6 1.6 0.015 15.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF48598.1 - 6.5e-06 25.4 0.6 0.047 13.2 0.1 2.5 2 0 0 2 2 2 2 EF hand Kelch_5 PF13854.6 OWF48599.1 - 2e-25 88.3 0.9 1.6e-06 27.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OWF48599.1 - 3.3e-25 87.5 3.0 1.7e-07 31.3 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OWF48599.1 - 1.8e-23 82.3 9.6 2.2e-09 37.3 0.3 6.7 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF48599.1 - 7.9e-22 77.0 11.2 6.1e-05 22.9 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF48599.1 - 2.3e-20 71.7 5.9 0.005 16.8 0.0 7.1 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OWF48599.1 - 1.6e-19 69.2 2.7 0.0027 17.3 0.0 5.6 6 0 0 6 6 6 5 Kelch motif EMP70 PF02990.16 OWF48600.1 - 1.9e-115 386.5 24.7 2.4e-115 386.2 24.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 CUB PF00431.20 OWF48601.1 - 1.2e-163 534.2 15.8 2.4e-41 140.5 0.4 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 OWF48601.1 - 1.4e-74 249.8 0.2 1.4e-74 249.8 0.2 1.9 2 0 0 2 2 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 OWF48601.1 - 9.1e-18 64.3 34.0 5.3e-11 42.6 11.5 3.5 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 OWF48601.1 - 3.6e-13 49.5 28.9 2.3e-06 27.7 9.2 3.0 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 OWF48601.1 - 4.3e-10 39.3 5.9 5.8e-05 22.9 0.4 3.0 2 0 0 2 2 2 2 Complement Clr-like EGF-like CUB_2 PF02408.20 OWF48601.1 - 2.5e-06 27.3 2.6 0.024 14.4 0.0 4.4 4 0 0 4 4 4 2 CUB-like domain EGF_3 PF12947.7 OWF48601.1 - 1.7e-05 24.9 26.9 0.00047 20.3 6.6 3.3 2 1 0 2 2 2 2 EGF domain EGF PF00008.27 OWF48601.1 - 5.6e-05 23.3 27.1 0.0017 18.6 5.0 3.8 2 1 1 3 3 3 2 EGF-like domain Reprolysin_4 PF13583.6 OWF48601.1 - 0.022 14.4 0.2 0.059 13.0 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like hEGF PF12661.7 OWF48601.1 - 0.045 14.4 17.8 0.66 10.7 3.8 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF Peptidase_M10 PF00413.24 OWF48601.1 - 0.048 13.5 0.6 0.45 10.3 0.3 2.3 1 1 1 2 2 2 0 Matrixin Plasmod_Pvs28 PF06247.11 OWF48601.1 - 3.9 7.9 23.8 2.6 8.4 8.5 3.3 2 0 0 2 2 2 0 Pvs28 EGF domain L_HMGIC_fpl PF10242.9 OWF48602.1 - 1.1e-40 139.8 2.5 1.2e-40 139.6 2.5 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 OWF48602.1 - 1.1e-11 44.9 2.0 2e-11 44.0 2.0 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.16 OWF48602.1 - 4.5e-06 25.8 4.9 0.00053 19.0 7.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PMP22_Claudin PF00822.20 OWF48602.1 - 0.0029 17.5 11.5 0.026 14.4 11.5 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 OWF48602.1 - 0.096 12.6 10.6 0.031 14.2 5.2 2.3 2 1 0 2 2 2 0 Tight junction protein, Claudin-like Phage_holin_1 PF04531.13 OWF48602.1 - 0.24 11.9 4.7 4.1 8.0 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage holin Astacin PF01400.24 OWF48603.1 - 1.2e-28 100.0 0.0 1.9e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) UPF0731 PF14982.6 OWF48604.1 - 0.00039 20.5 11.0 26 5.1 0.0 8.0 1 1 7 9 9 9 1 UPF0731 family YwcE PF17368.2 OWF48604.1 - 0.097 13.3 2.3 66 4.3 0.0 3.9 1 1 2 4 4 4 0 Spore morphogenesis and germination YwcE SmpB PF01668.18 OWF48604.1 - 0.25 11.2 2.4 20 5.0 0.1 4.0 3 1 2 5 5 5 0 SmpB protein Glyco_transf_11 PF01531.16 OWF48606.1 - 1.6e-30 106.3 3.7 2.2e-30 105.9 3.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 Terminase_4 PF05119.12 OWF48606.1 - 0.13 12.7 0.3 5.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit Pribosyltran PF00156.27 OWF48607.1 - 2.1e-11 43.6 0.0 4.5e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.6 OWF48607.1 - 6.4e-08 32.6 0.0 2.8e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OWF48607.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain LPMO_10 PF03067.15 OWF48608.1 - 2.7e-28 100.0 0.8 2.7e-28 100.0 0.8 2.5 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cadherin PF00028.17 OWF48609.1 - 1.9e-17 63.5 22.6 4.3e-06 27.1 0.3 6.1 6 0 0 6 6 6 4 Cadherin domain Cadherin_3 PF16184.5 OWF48609.1 - 0.0091 16.0 0.2 0.18 11.8 0.1 3.2 3 0 0 3 3 3 1 Cadherin-like DUF5586 PF17824.1 OWF48610.1 - 8.4e-16 58.1 13.2 3.9e-08 32.8 3.2 3.1 2 2 0 2 2 2 2 Family of unknown function (DUF5586) DUF5582 PF17819.1 OWF48610.1 - 0.18 12.3 3.8 0.17 12.3 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5582) Mab-21 PF03281.14 OWF48611.1 - 1.1e-23 84.0 1.4 1.7e-23 83.4 1.4 1.3 1 0 0 1 1 1 1 Mab-21 protein Imm3 PF14425.6 OWF48611.1 - 0.043 13.9 0.1 0.85 9.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein Imm3 Nucleoporin_FG PF13634.6 OWF48612.1 - 8.5e-09 36.2 18.9 0.00045 21.0 3.4 2.2 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF1983 PF09327.11 OWF48612.1 - 0.0016 18.5 5.6 4.2 7.5 0.1 4.8 1 1 5 8 8 8 2 Domain of unknown function (DUF1983) MAM PF00629.23 OWF48612.1 - 0.024 14.6 7.5 0.48 10.3 7.5 2.6 1 1 0 1 1 1 0 MAM domain, meprin/A5/mu SpmSyn_N PF17950.1 OWF48612.1 - 0.29 11.3 10.6 14 5.9 0.1 3.9 1 1 3 4 4 4 0 S-adenosylmethionine decarboxylase N -terminal TLP-20 PF06088.11 OWF48612.1 - 0.62 9.9 20.1 1.1 9.1 0.8 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SUN PF03856.13 OWF48612.1 - 0.65 9.4 9.2 2.2 7.7 0.4 2.8 1 1 0 2 2 2 0 Beta-glucosidase (SUN family) VasI PF11319.8 OWF48612.1 - 0.71 9.5 7.6 2.3 7.8 2.9 2.5 1 1 1 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 DUF916 PF06030.12 OWF48612.1 - 1.9 8.6 27.4 1 9.5 3.8 3.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF916) MHC_II_beta PF00969.19 OWF48612.1 - 3.6 7.8 8.1 22 5.3 0.1 4.5 3 3 2 5 5 5 0 Class II histocompatibility antigen, beta domain Plus-3 PF03126.18 OWF48612.1 - 5.4 7.6 15.3 20 5.7 1.7 3.2 1 1 2 3 3 3 0 Plus-3 domain Pilin_N PF07790.11 OWF48612.1 - 6 7.9 6.9 1.2e+02 3.7 0.4 3.9 1 1 1 2 2 2 0 Archaeal Type IV pilin, N-terminal Sulfatase PF00884.23 OWF48613.1 - 1.9e-58 198.3 1.3 3.1e-58 197.6 1.3 1.4 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.8 OWF48613.1 - 2.5e-12 47.5 2.6 2.5e-12 47.5 2.6 2.6 3 0 0 3 3 3 1 Sulfatase protein Phosphodiest PF01663.22 OWF48613.1 - 7.1e-05 22.6 4.2 0.0004 20.1 1.6 2.9 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF5344 PF17279.2 OWF48613.1 - 0.35 11.5 2.8 31 5.2 0.6 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5344) zf-C2H2 PF00096.26 OWF48614.1 - 4.7e-26 89.8 33.7 4.7e-07 29.9 2.1 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF48614.1 - 3.5e-25 87.3 43.9 5.1e-07 29.8 1.2 5.8 6 0 0 6 6 5 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF48614.1 - 1.6e-19 68.9 30.7 0.00029 21.4 1.3 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF48614.1 - 6.9e-14 51.4 24.0 0.00041 20.3 0.8 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF48614.1 - 1.4e-13 50.8 12.7 0.0059 16.9 0.2 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OWF48614.1 - 6.5e-06 26.4 18.7 0.0035 17.6 3.5 3.4 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OWF48614.1 - 1.3e-05 25.4 13.2 0.91 10.0 0.3 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 OWF48614.1 - 0.0049 17.0 12.3 0.53 10.4 0.8 3.8 1 1 4 5 5 5 3 Zinc ribbon domain BolA PF01722.18 OWF48614.1 - 0.01 16.1 0.0 0.01 16.1 0.0 2.7 3 1 1 4 4 2 0 BolA-like protein Zn_ribbon_SprT PF17283.2 OWF48614.1 - 0.02 14.8 2.4 0.02 14.8 2.4 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 OWF48614.1 - 0.034 13.7 11.0 1.6 8.4 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger DUF1524 PF07510.11 OWF48614.1 - 0.061 13.2 1.3 0.1 12.5 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1524) zinc_ribbon_9 PF14369.6 OWF48614.1 - 0.086 13.1 7.9 0.68 10.2 0.0 3.3 4 0 0 4 4 3 0 zinc-ribbon ADK_lid PF05191.14 OWF48614.1 - 0.087 12.8 18.5 0.76 9.8 4.2 3.9 4 0 0 4 4 3 0 Adenylate kinase, active site lid CpXC PF14353.6 OWF48614.1 - 0.15 12.1 11.6 7.5 6.6 0.6 4.4 3 1 1 4 4 4 0 CpXC protein zf-CCHC_5 PF14787.6 OWF48614.1 - 0.22 11.3 5.4 2.2 8.1 0.1 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Prok-RING_1 PF14446.6 OWF48614.1 - 0.35 10.8 16.0 8.2 6.4 0.1 4.9 4 1 0 5 5 5 0 Prokaryotic RING finger family 1 zf-C2HC_2 PF13913.6 OWF48614.1 - 0.82 9.6 21.0 3.2 7.7 0.7 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type GAGA PF09237.11 OWF48614.1 - 0.85 9.5 9.4 0.16 11.8 0.4 2.9 2 1 1 3 3 2 0 GAGA factor DZR PF12773.7 OWF48614.1 - 0.88 9.6 16.0 1.1e+03 -0.2 16.0 3.2 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 OWF48614.1 - 0.98 9.4 17.2 7.2 6.6 0.8 4.0 2 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3268 PF11672.8 OWF48614.1 - 1.1 9.6 10.0 0.98 9.8 0.6 3.0 2 1 1 3 3 3 0 zinc-finger-containing domain zinc_ribbon_10 PF10058.9 OWF48614.1 - 1.5 8.6 9.6 1.5 8.6 4.2 3.0 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc-ribbons_6 PF07191.12 OWF48614.1 - 2.7 8.0 12.0 2e+02 2.0 0.1 3.3 1 1 1 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 OWF48614.1 - 3.1 7.3 13.5 6.5 6.3 1.0 4.3 4 0 0 4 4 4 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 OWF48614.1 - 3.2 7.9 12.0 0.16 12.0 0.7 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-AN1 PF01428.16 OWF48614.1 - 3.8 7.8 19.3 10 6.4 0.2 5.2 5 0 0 5 5 5 0 AN1-like Zinc finger zinc_ribbon_15 PF17032.5 OWF48614.1 - 4.4 8.1 12.6 12 6.7 5.1 2.9 1 1 0 2 2 2 0 zinc-ribbon family zf-C2H2_9 PF16293.5 OWF48614.1 - 6.2 6.8 8.4 1.6 8.6 0.2 3.6 4 0 0 4 4 3 0 C2H2 type zinc-finger (1 copy) Cript PF10235.9 OWF48614.1 - 8.7 7.0 16.1 1.5 9.5 1.4 4.4 1 1 3 4 4 4 0 Microtubule-associated protein CRIPT 7tm_1 PF00001.21 OWF48615.1 - 5.1e-37 127.6 5.8 6.3e-37 127.3 5.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF48615.1 - 1.4e-09 38.0 14.0 1.4e-09 38.0 14.0 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF48615.1 - 1.9e-06 27.5 2.7 1.9e-06 27.5 2.7 3.0 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 OWF48615.1 - 9.7e-05 22.2 8.8 9.7e-05 22.2 8.8 2.3 2 1 0 2 2 2 1 Olfactory receptor DUF2116 PF09889.9 OWF48615.1 - 0.0098 15.9 0.2 0.0098 15.9 0.2 3.4 4 1 1 5 5 5 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) Stevor PF17410.2 OWF48615.1 - 0.021 14.4 7.9 0.1 12.1 0.2 3.2 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame 7TM_GPCR_Srt PF10321.9 OWF48615.1 - 0.22 10.5 25.5 1.3 8.0 16.7 3.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt Orf78 PF06024.12 OWF48615.1 - 0.73 10.2 8.2 8.1 6.8 0.1 3.7 3 0 0 3 3 3 0 Orf78 (ac78) Git3 PF11710.8 OWF48615.1 - 0.78 9.5 22.4 0.032 14.0 16.1 1.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 HEPN_DZIP3 PF18738.1 OWF48616.1 - 7.2e-30 103.6 0.2 1.5e-29 102.6 0.2 1.5 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN PDZ_3 PF17815.1 OWF48616.1 - 5.3 6.9 5.5 1.1e+02 2.6 5.5 2.3 1 1 0 1 1 1 0 PDZ domain IPK PF03770.16 OWF48617.1 - 9.8e-60 201.8 0.1 1.7e-59 201.0 0.1 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase UPF0231 PF06062.11 OWF48617.1 - 0.037 14.3 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) Ank_2 PF12796.7 OWF48618.1 - 2.6e-157 511.8 62.4 1.6e-19 70.3 1.1 14.7 2 1 15 17 17 17 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48618.1 - 5.8e-128 415.8 29.1 5.8e-16 58.6 0.2 18.2 12 4 5 18 18 18 16 Ankyrin repeats (many copies) Ank PF00023.30 OWF48618.1 - 1.7e-113 366.6 57.3 6.8e-08 32.6 0.8 29.2 27 2 2 29 29 29 24 Ankyrin repeat Ank_3 PF13606.6 OWF48618.1 - 6.4e-111 348.7 24.9 7.6e-06 25.9 0.2 29.0 29 0 0 29 29 29 24 Ankyrin repeat Ank_5 PF13857.6 OWF48618.1 - 2.2e-100 327.4 36.9 1.2e-09 38.2 0.5 24.0 6 3 17 24 24 24 22 Ankyrin repeats (many copies) Ion_trans PF00520.31 OWF48618.1 - 1.9e-10 40.4 20.9 5.8e-10 38.8 20.9 1.7 1 1 0 1 1 1 1 Ion transport protein DUF3447 PF11929.8 OWF48618.1 - 0.042 13.8 0.8 11 6.0 0.0 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) DUF2520 PF10728.9 OWF48618.1 - 0.11 12.3 4.6 3.3 7.5 0.0 4.9 5 1 1 6 6 6 0 Domain of unknown function (DUF2520) PKD_channel PF08016.12 OWF48618.1 - 4.8 5.7 13.8 1.6 7.3 3.6 2.5 2 0 0 2 2 2 0 Polycystin cation channel DUF21 PF01595.20 OWF48618.1 - 5.8 6.6 9.6 0.057 13.1 0.9 2.1 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain RrnaAD PF00398.20 OWF48619.1 - 9.2e-38 129.8 0.0 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OWF48619.1 - 0.013 16.2 0.0 0.033 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 OWF48619.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PELOTA_1 PF15608.6 OWF48619.1 - 0.15 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 PELOTA RNA binding domain XK-related PF09815.9 OWF48620.1 - 2.6e-91 306.2 32.4 3.2e-91 305.9 32.4 1.1 1 0 0 1 1 1 1 XK-related protein CarboxypepD_reg PF13620.6 OWF48620.1 - 0.081 13.2 1.6 4.3 7.7 0.1 3.3 1 1 1 3 3 3 0 Carboxypeptidase regulatory-like domain BSD PF03909.17 OWF48621.1 - 3.1e-13 49.5 0.2 3.1e-13 49.5 0.2 2.2 2 0 0 2 2 2 1 BSD domain Integrin_beta PF00362.18 OWF48621.1 - 0.0081 15.9 0.2 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain SAM_1 PF00536.30 OWF48622.1 - 0.036 14.5 0.0 0.071 13.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CABIT PF12736.7 OWF48623.1 - 9.3e-09 35.0 0.0 1.8e-06 27.5 0.0 2.3 1 1 0 2 2 2 2 Cell-cycle sustaining, positive selection, CABIT PF12736.7 OWF48624.1 - 5.4e-08 32.5 0.1 0.0017 17.8 0.0 2.9 2 1 0 2 2 2 2 Cell-cycle sustaining, positive selection, TMEM154 PF15102.6 OWF48625.1 - 0.0044 16.9 1.6 0.032 14.1 0.1 2.1 2 0 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 OWF48625.1 - 0.034 14.4 0.2 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) Homeodomain PF00046.29 OWF48627.1 - 2.1e-24 85.1 6.1 4.7e-24 84.0 6.1 1.7 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 OWF48627.1 - 3e-07 30.0 2.6 3e-07 30.0 2.6 1.9 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.11 OWF48627.1 - 0.015 15.2 0.1 0.059 13.3 0.1 2.1 1 0 0 1 1 1 0 Homeobox KN domain PDDEXK_6 PF04720.12 OWF48627.1 - 1.7 8.5 8.0 0.22 11.5 3.6 1.7 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Anemone_cytotox PF06369.12 OWF48628.1 - 1.2e-07 31.6 0.3 1.3e-07 31.4 0.3 1.2 1 0 0 1 1 1 1 Sea anemone cytotoxic protein dsDNA_bind PF01984.20 OWF48629.1 - 4.4e-07 30.2 0.4 18 5.6 0.0 6.6 1 1 5 6 6 6 2 Double-stranded DNA-binding domain MgtE_N PF03448.17 OWF48629.1 - 7.9e-06 26.4 20.0 0.0026 18.3 1.4 3.2 1 1 1 3 3 3 3 MgtE intracellular N domain LodA_N PF17990.1 OWF48629.1 - 0.078 12.9 5.2 5.8 6.8 0.2 3.6 1 1 2 3 3 3 0 L-Lysine epsilon oxidase N-terminal Spore_Cse60 PF10957.8 OWF48629.1 - 3.2 7.9 32.9 43 4.2 0.2 8.9 1 1 6 8 8 8 0 Sporulation protein Cse60 Top6b_C PF18000.1 OWF48629.1 - 4 7.6 27.5 34 4.6 6.0 6.8 1 1 6 7 7 7 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain DUF637 PF04830.13 OWF48630.1 - 0.083 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) MFS_1 PF07690.16 OWF48631.1 - 6.3e-21 74.7 9.9 6.3e-21 74.7 9.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 OWF48631.1 - 3.9 7.9 7.4 33 4.9 0.3 3.7 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF1907 PF08925.11 OWF48632.1 - 7.4e-119 396.4 0.0 8.4e-119 396.2 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Lectin_C PF00059.21 OWF48633.1 - 7.3e-23 81.4 5.6 1.8e-10 41.5 1.5 2.8 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 OWF48633.1 - 0.00042 20.0 4.1 0.1 12.3 0.0 3.6 3 1 0 3 3 3 1 UL45 protein, carbohydrate-binding C-type lectin-like SNCAIP_SNCA_bd PF16700.5 OWF48633.1 - 0.00042 20.0 0.3 0.00091 18.9 0.3 1.4 1 0 0 1 1 1 1 Synphilin-1 alpha-Synuclein-binding domain DUF1741 PF08427.10 OWF48633.1 - 0.012 15.3 2.2 0.021 14.5 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Podoplanin PF05808.11 OWF48633.1 - 0.084 13.0 0.4 1.6 8.9 0.4 2.3 2 0 0 2 2 2 0 Podoplanin CBM_14 PF01607.24 OWF48633.1 - 0.09 13.0 1.6 0.32 11.2 1.6 1.9 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Xlink PF00193.17 OWF48633.1 - 8.7 6.8 8.1 8.8 6.8 0.0 4.1 4 1 0 4 4 4 0 Extracellular link domain Stomoxyn PF11585.8 OWF48634.1 - 2.2 8.4 9.0 64 3.7 0.2 4.7 3 1 3 6 6 6 0 Insect antimicrobial peptide, stomoxyn Cupin_2 PF07883.11 OWF48635.1 - 0.07 12.8 2.7 3.8 7.3 0.6 2.5 1 1 1 2 2 2 0 Cupin domain DUF346 PF03984.13 OWF48635.1 - 0.08 12.7 0.0 20 5.0 0.0 2.9 3 1 0 3 3 3 0 Repeat of unknown function (DUF346) Caudo_bapla16 PF16792.5 OWF48635.1 - 0.56 9.1 4.7 7.1 5.5 0.3 2.0 1 1 1 2 2 2 0 Phage tail base-plate attachment protein of Caudovirales ORF16 Peptidase_C53 PF05550.11 OWF48635.1 - 0.77 9.4 4.8 25 4.5 0.1 3.4 1 1 3 4 4 4 0 Pestivirus Npro endopeptidase C53 Cdc6_C PF09079.11 OWF48635.1 - 2.9 7.9 4.9 31 4.6 0.1 3.6 2 1 2 4 4 4 0 CDC6, C terminal winged helix domain FAD_binding_3 PF01494.19 OWF48636.1 - 8.4e-18 64.7 0.0 1.6e-17 63.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OWF48636.1 - 1.5e-07 30.7 0.0 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 OWF48636.1 - 2.3e-07 30.7 0.0 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF48636.1 - 2.7e-06 27.5 0.0 9e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF48636.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OWF48636.1 - 4.3e-05 22.9 0.0 9.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF48636.1 - 0.00036 19.4 0.0 0.0006 18.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OWF48636.1 - 0.00036 19.7 0.0 0.0008 18.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OWF48636.1 - 0.00064 18.9 0.0 0.00091 18.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OWF48636.1 - 0.00072 18.7 0.0 0.96 8.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 OWF48636.1 - 0.0028 18.2 0.0 0.0089 16.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF48636.1 - 0.0034 16.7 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OWF48636.1 - 0.025 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.7 OWF48636.1 - 0.046 13.1 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3024 PF11225.8 OWF48636.1 - 0.062 13.6 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) IP_trans PF02121.18 OWF48637.1 - 9.5e-103 343.1 3.3 1.4e-102 342.5 3.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein ABC_membrane PF00664.23 OWF48638.1 - 1.4e-66 224.9 43.2 2e-36 126.0 14.2 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF48638.1 - 7e-50 169.1 0.2 2.5e-29 102.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 OWF48638.1 - 1.3e-06 28.5 1.0 0.022 14.9 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF48638.1 - 2.5e-06 27.5 0.3 0.00067 19.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OWF48638.1 - 2.7e-06 27.0 2.5 0.024 14.1 0.0 4.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 OWF48638.1 - 1e-05 25.2 0.0 0.0041 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF48638.1 - 8.1e-05 23.1 0.7 0.045 14.1 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain Dynamin_N PF00350.23 OWF48638.1 - 0.00077 19.6 1.2 0.013 15.6 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 OWF48638.1 - 0.0023 17.7 2.1 1.5 8.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain P53_TAD PF08563.11 OWF48638.1 - 0.0038 16.7 1.3 0.0087 15.5 0.1 2.3 2 0 0 2 2 2 1 P53 transactivation motif Zeta_toxin PF06414.12 OWF48638.1 - 0.0049 16.2 0.7 0.067 12.5 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 OWF48638.1 - 0.006 16.1 0.5 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 OWF48638.1 - 0.013 16.0 0.2 5.2 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OWF48638.1 - 0.018 15.2 5.6 0.74 9.9 0.8 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 OWF48638.1 - 0.019 15.2 1.3 3.6 7.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 OWF48638.1 - 0.024 14.9 0.5 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OWF48638.1 - 0.032 13.9 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OWF48638.1 - 0.059 12.3 0.1 4.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 OWF48638.1 - 0.14 12.0 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 OWF48638.1 - 9.8 5.7 6.1 3.7 7.1 0.3 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Homeodomain PF00046.29 OWF48639.1 - 8e-12 44.8 1.1 8.3e-10 38.4 0.1 2.6 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 OWF48639.1 - 2.7e-09 36.8 0.2 6.7e-09 35.5 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain HOCHOB PF17943.1 OWF48639.1 - 0.0053 17.4 0.3 2.4 8.9 0.0 3.1 2 1 1 3 3 3 2 Homeobox-cysteine loop-homeobox Homez PF11569.8 OWF48639.1 - 0.056 12.9 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zinc_ribbon_9 PF14369.6 OWF48639.1 - 6.3 7.1 8.6 4.2 7.7 2.2 2.8 2 1 0 2 2 2 0 zinc-ribbon Ras PF00071.22 OWF48640.1 - 2.8e-29 101.8 0.0 1e-28 100.0 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF48640.1 - 2.4e-10 40.7 0.0 2.3e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF48640.1 - 1.6e-07 31.0 0.0 0.00088 18.8 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 OWF48640.1 - 0.00046 19.4 0.0 0.00066 18.9 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 OWF48640.1 - 0.0043 16.5 0.0 0.011 15.1 0.0 1.7 1 1 1 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 OWF48640.1 - 0.0063 16.8 0.0 0.053 13.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OWF48640.1 - 0.007 16.4 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF48640.1 - 0.0079 16.1 0.0 3.7 7.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OWF48640.1 - 0.01 15.6 0.0 0.042 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OWF48640.1 - 0.034 14.5 0.0 0.047 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OWF48640.1 - 0.042 14.3 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OWF48640.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF48640.1 - 0.05 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 OWF48640.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 OWF48640.1 - 0.087 12.6 0.1 3.6 7.3 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 OWF48640.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.18 OWF48640.1 - 0.12 11.7 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family MNR PF15718.5 OWF48641.1 - 3.2e-93 313.6 30.7 2.6e-91 307.3 30.7 2.6 1 1 0 1 1 1 1 Protein moonraker PEP-utilisers_N PF05524.13 OWF48641.1 - 0.56 10.4 5.6 26 5.0 0.0 3.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF2721 PF11026.8 OWF48642.1 - 0.088 12.7 6.5 0.13 12.1 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2207 PF09972.9 OWF48642.1 - 0.47 9.2 2.0 0.65 8.7 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 OWF48642.1 - 1.4 8.5 5.4 2.5 7.7 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EF-hand_4 PF12763.7 OWF48643.1 - 0.00097 19.1 0.0 0.0054 16.7 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand ANF_receptor PF01094.28 OWF48644.1 - 1.1e-38 133.2 0.1 1.4e-38 133.0 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF48644.1 - 0.0054 16.4 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Guanylate_cyc PF00211.20 OWF48646.1 - 5.7e-60 202.1 0.2 1.2e-59 201.0 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF48646.1 - 2.4e-27 95.8 0.0 5.1e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF48646.1 - 4.5e-27 95.1 0.0 8e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF48646.1 - 0.0024 17.4 1.3 0.0079 15.7 0.2 2.0 2 0 0 2 2 2 1 Heme NO binding associated zf-A20 PF01754.16 OWF48646.1 - 0.025 14.5 0.5 0.057 13.4 0.5 1.6 1 0 0 1 1 1 0 A20-like zinc finger Apt1 PF10351.9 OWF48647.1 - 6.3e-96 322.1 18.3 5.4e-66 223.4 8.5 2.9 3 1 1 4 4 4 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 OWF48647.1 - 3.4e-28 98.7 2.9 4.4e-28 98.4 0.0 2.8 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 OWF48647.1 - 1.2e-08 35.0 1.2 4.4e-08 33.2 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) KCNQ2_u3 PF16642.5 OWF48647.1 - 0.026 15.5 0.2 0.18 12.8 0.2 2.5 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Med13_C PF06333.12 OWF48648.1 - 1.2e-99 333.8 0.1 1.2e-99 333.8 0.1 4.8 5 0 0 5 5 5 2 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 OWF48648.1 - 4.7e-61 206.7 0.2 4.7e-61 206.7 0.2 2.1 2 0 0 2 2 2 1 MID domain of medPIWI Med13_N PF11597.8 OWF48648.1 - 1.5e-28 100.1 1.0 3.8e-28 98.8 0.2 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Sulfotransfer_1 PF00685.27 OWF48649.1 - 8.1e-10 38.6 0.3 1.9e-08 34.1 0.1 2.1 1 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF48649.1 - 1.9e-06 28.4 0.2 5e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family DUF4573 PF15140.6 OWF48650.1 - 1.4e-19 70.6 26.0 4.2e-09 36.5 2.8 2.6 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) Plasmodium_HRP PF05403.11 OWF48650.1 - 1.1e-10 41.8 204.1 0.077 12.8 38.1 6.6 2 2 4 6 6 6 6 Plasmodium histidine-rich protein (HRPII/III) DUF365 PF04033.12 OWF48650.1 - 0.033 14.5 28.6 2.5 8.4 0.7 8.1 2 2 8 11 11 11 0 Domain of unknown function (DUF365) AbiEi_3 PF11459.8 OWF48650.1 - 1.1 9.0 3.9 12 5.6 0.0 4.0 3 1 2 5 5 5 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system HTH_39 PF14090.6 OWF48650.1 - 2.7 7.8 4.0 48 3.8 0.1 3.9 3 1 1 4 4 4 0 Helix-turn-helix domain LPMO_10 PF03067.15 OWF48652.1 - 1e-35 124.2 4.6 1.9e-35 123.3 4.6 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SecD_SecF PF02355.16 OWF48652.1 - 0.019 14.4 0.4 0.028 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein export membrane protein LPMO_10 PF03067.15 OWF48653.1 - 5.7e-36 125.0 5.6 8.9e-36 124.4 5.6 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 OWF48654.1 - 2.5e-35 122.9 5.5 5e-35 121.9 5.5 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading OLF PF02191.16 OWF48655.1 - 2.2e-63 214.1 0.0 3.2e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Usp PF00582.26 OWF48656.1 - 8.1e-06 26.4 0.0 8.6e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Neur_chan_memb PF02932.16 OWF48657.1 - 4.8e-17 62.8 7.9 4.8e-17 62.8 7.9 2.0 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Plasmodium_Vir PF05795.11 OWF48657.1 - 0.047 13.1 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_LBD PF02931.23 OWF48658.1 - 3.6e-30 105.0 0.3 4.3e-30 104.8 0.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 OWF48659.1 - 1.6e-30 106.2 0.9 2.6e-30 105.5 0.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48659.1 - 6.5e-15 55.8 12.5 3.3e-12 47.0 10.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Globin PF00042.22 OWF48660.1 - 1.8e-11 44.6 0.0 2.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Globin SERTA PF06031.13 OWF48661.1 - 2.9e-14 52.4 1.1 5.8e-14 51.5 1.1 1.6 1 0 0 1 1 1 1 SERTA motif DUF2040 PF09745.9 OWF48661.1 - 0.017 15.2 3.4 0.036 14.1 3.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Ig_3 PF13927.6 OWF48663.1 - 5.4e-63 209.6 7.6 1.6e-13 51.0 1.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 OWF48663.1 - 4.3e-54 180.6 0.0 1.1e-11 44.6 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF48663.1 - 4.6e-45 151.8 14.6 1.3e-09 38.3 0.5 6.6 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 OWF48663.1 - 1.1e-30 105.8 10.3 1e-09 38.6 0.0 5.0 4 0 0 4 4 4 4 Fibronectin type III domain ig PF00047.25 OWF48663.1 - 2.9e-29 101.0 5.5 9.7e-05 22.5 0.6 6.8 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 OWF48663.1 - 6e-20 71.4 15.6 0.0005 20.2 0.1 9.5 6 4 2 8 8 8 5 Immunoglobulin V-set domain Ig_5 PF16681.5 OWF48663.1 - 1.8e-10 41.0 0.0 1.1 9.7 0.0 6.8 6 1 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF48663.1 - 2.2e-08 33.5 0.7 1.3 8.6 0.0 6.2 6 0 0 6 6 6 2 Immunoglobulin domain UL45 PF05473.12 OWF48663.1 - 2.2e-07 30.7 0.0 5.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like C2-set_2 PF08205.12 OWF48663.1 - 4.2e-06 26.7 1.2 0.18 11.9 0.1 4.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Lectin_C PF00059.21 OWF48663.1 - 5e-06 27.2 1.1 1e-05 26.2 0.1 2.0 2 0 0 2 2 2 1 Lectin C-type domain Izumo-Ig PF16706.5 OWF48663.1 - 1.2e-05 25.3 1.8 1 9.5 0.0 5.4 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 OWF48663.1 - 0.00063 20.3 0.0 0.00063 20.3 0.0 5.2 5 0 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF48663.1 - 0.0062 16.8 0.0 5.8 7.3 0.0 3.0 3 0 0 3 3 2 1 Interferon-alpha/beta receptor, fibronectin type III V-set_CD47 PF08204.11 OWF48663.1 - 0.038 14.0 7.4 3.4 7.7 0.2 4.8 3 1 1 4 4 4 0 CD47 immunoglobulin-like domain C2-set PF05790.15 OWF48663.1 - 0.085 13.1 0.3 8.6 6.6 0.0 3.8 3 1 1 4 4 4 0 Immunoglobulin C2-set domain Receptor_2B4 PF11465.8 OWF48663.1 - 0.14 12.3 0.1 15 5.9 0.0 3.6 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Homeodomain PF00046.29 OWF48664.1 - 2.1e-23 81.9 7.3 3.8e-23 81.1 7.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF48664.1 - 0.13 12.2 0.2 0.29 11.0 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Orn_Arg_deC_N PF02784.16 OWF48665.1 - 8.9e-74 248.0 0.0 1.2e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF48665.1 - 4.5e-10 39.6 0.0 9e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OWF48665.1 - 0.047 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Orn_Arg_deC_N PF02784.16 OWF48666.1 - 2.6e-72 243.2 0.0 3.4e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF48666.1 - 7.3e-12 45.4 0.0 8.6e-09 35.5 0.0 2.4 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OWF48666.1 - 0.00036 20.0 0.0 0.00068 19.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel zf-B_box PF00643.24 OWF48667.1 - 1.2e-10 41.4 22.3 5.3e-06 26.5 3.5 2.5 2 0 0 2 2 2 2 B-box zinc finger Orn_Arg_deC_N PF02784.16 OWF48668.1 - 5.9e-123 409.0 0.1 1.5e-70 237.4 0.0 2.9 2 1 1 3 3 3 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF48668.1 - 2.4e-24 85.4 0.4 1.7e-10 41.0 0.0 3.8 3 1 0 4 4 4 2 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ClpS PF02617.17 OWF48668.1 - 0.53 10.1 4.6 0.93 9.3 0.0 3.2 4 0 0 4 4 4 0 ATP-dependent Clp protease adaptor protein ClpS Orn_Arg_deC_N PF02784.16 OWF48669.1 - 2.2e-67 227.0 0.1 7.4e-67 225.3 0.1 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF48669.1 - 2e-08 34.3 0.0 4.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 OWF48670.1 - 4.3e-72 242.4 0.0 6.9e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF48670.1 - 1.1e-11 44.8 0.1 9.3e-11 41.8 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 OWF48671.1 - 2.5e-11 43.4 0.1 3.5e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF48671.1 - 7.3e-09 35.7 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 OWF48672.1 - 2.8e-15 56.4 0.0 3.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain CUB PF00431.20 OWF48674.1 - 0 2208.4 14.2 3.8e-33 114.1 0.0 26.1 26 0 0 26 26 26 26 CUB domain EGF PF00008.27 OWF48674.1 - 1.9e-19 69.6 117.2 4.4e-06 26.9 6.3 9.1 8 0 0 8 8 7 6 EGF-like domain CUB_2 PF02408.20 OWF48674.1 - 8.5e-19 67.5 48.9 0.098 12.4 0.0 18.8 21 0 0 21 21 21 8 CUB-like domain EGF_CA PF07645.15 OWF48674.1 - 7.4e-17 61.3 127.6 5.1e-05 23.4 13.7 8.9 6 2 2 8 8 8 7 Calcium-binding EGF domain hEGF PF12661.7 OWF48674.1 - 1.1e-13 51.3 82.3 5.7e-05 23.6 3.4 8.1 7 0 0 7 7 7 6 Human growth factor-like EGF EGF_3 PF12947.7 OWF48674.1 - 1.5e-11 44.3 116.4 1.6e-09 37.8 6.8 9.6 7 1 1 8 8 8 4 EGF domain cEGF PF12662.7 OWF48674.1 - 0.00046 20.1 3.6 0.00046 20.1 3.6 9.0 9 0 0 9 9 9 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF48674.1 - 0.00082 19.6 121.4 0.003 17.8 10.7 9.4 6 3 3 9 9 9 5 Coagulation Factor Xa inhibitory site Dynamitin PF04912.14 OWF48674.1 - 0.023 14.0 1.3 0.033 13.5 1.3 1.1 1 0 0 1 1 1 0 Dynamitin Nup35_RRM_2 PF14605.6 OWF48674.1 - 0.091 12.8 0.0 55 3.9 0.0 4.6 5 0 0 5 5 3 0 Nup53/35/40-type RNA recognition motif Crp PF00325.20 OWF48674.1 - 0.62 9.8 3.5 12 5.6 0.0 4.5 5 0 0 5 5 5 0 Bacterial regulatory proteins, crp family HEXIM PF15313.6 OWF48675.1 - 2e-44 151.2 13.7 2e-44 151.2 13.7 2.4 3 0 0 3 3 3 1 Hexamethylene bis-acetamide-inducible protein Mst1_SARAH PF11629.8 OWF48675.1 - 0.085 13.0 9.0 0.16 12.1 6.2 2.6 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 BRO1 PF03097.18 OWF48676.1 - 2.1e-114 382.3 8.9 2.1e-114 382.3 8.9 2.1 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OWF48676.1 - 1.2e-90 303.8 8.8 1.2e-90 303.8 8.8 2.3 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Kinesin_assoc PF16183.5 OWF48676.1 - 0.028 14.6 0.6 0.028 14.6 0.6 2.6 3 0 0 3 3 3 0 Kinesin-associated DUF4618 PF15397.6 OWF48676.1 - 0.95 8.8 8.9 0.4 10.1 2.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 OWF48676.1 - 8.9 6.5 12.5 12 6.1 1.9 3.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 OWF48676.1 - 9.6 5.4 9.1 63 2.8 9.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) THAP PF05485.12 OWF48677.1 - 2.9e-11 44.1 0.4 3.4e-11 43.9 0.4 1.0 1 0 0 1 1 1 1 THAP domain QVR PF17064.5 OWF48678.1 - 1e-25 89.8 7.3 1.3e-25 89.4 7.3 1.2 1 0 0 1 1 1 1 Sleepless protein Cys_knot PF00007.22 OWF48678.1 - 0.018 15.4 5.3 0.03 14.6 5.3 1.3 1 0 0 1 1 1 0 Cystine-knot domain PDEase_I PF00233.19 OWF48679.1 - 2.5e-77 259.8 2.0 4.6e-77 258.9 0.7 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OWF48679.1 - 2.7e-29 102.5 0.0 1.6e-14 54.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 OWF48679.1 - 7.5e-13 49.0 0.0 2.5e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 OWF48679.1 - 2.4e-06 27.9 0.0 1.4 9.2 0.0 3.4 3 0 0 3 3 3 3 GAF domain HD PF01966.22 OWF48679.1 - 0.13 12.5 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 HD domain WSC PF01822.19 OWF48680.1 - 0.00015 21.9 7.7 0.00015 21.9 7.7 5.4 6 0 0 6 6 6 1 WSC domain Lectin_C PF00059.21 OWF48680.1 - 0.12 13.1 36.5 0.48 11.2 3.1 6.9 6 3 2 8 8 8 0 Lectin C-type domain GATA PF00320.27 OWF48681.1 - 2e-07 30.5 4.7 3.7e-07 29.6 4.7 1.4 1 0 0 1 1 1 1 GATA zinc finger SHMT PF00464.19 OWF48682.1 - 5.8e-202 670.6 0.0 6.8e-202 670.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 OWF48682.1 - 3.7e-05 23.1 0.0 0.00017 20.9 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class I and II DUF349 PF03993.12 OWF48682.1 - 0.42 11.0 2.4 6.3 7.2 0.4 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) HlyIII PF03006.20 OWF48683.1 - 1.6e-39 136.0 13.6 2.4e-39 135.4 13.6 1.3 1 0 0 1 1 1 1 Haemolysin-III related Condensin2nSMC PF12422.8 OWF48684.1 - 3.1e-50 170.2 2.3 2.1e-48 164.3 0.0 3.7 4 0 0 4 4 4 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 OWF48684.1 - 0.00066 19.7 10.3 0.52 10.7 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 OWF48684.1 - 0.0073 16.4 4.8 0.067 13.2 3.1 2.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF4810 PF16068.5 OWF48684.1 - 0.12 12.9 0.0 1.8 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) UBN_AB PF14075.6 OWF48684.1 - 0.29 10.8 0.0 0.29 10.8 0.0 3.0 3 0 0 3 3 3 0 Ubinuclein conserved middle domain bZIP_2 PF07716.15 OWF48685.1 - 1.6e-10 40.9 12.8 1.6e-10 40.9 12.8 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF48685.1 - 4.4e-05 23.5 9.4 4.4e-05 23.5 9.4 1.9 2 0 0 2 2 2 1 bZIP transcription factor Pkinase PF00069.25 OWF48686.1 - 1.2e-33 116.7 0.0 2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF48686.1 - 9e-31 107.1 0.0 1.8e-30 106.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 OWF48686.1 - 1.5e-07 32.4 19.9 3.3e-07 31.3 19.9 1.6 1 0 0 1 1 1 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 OWF48686.1 - 3.1e-06 26.2 0.0 5.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TMEM154 PF15102.6 OWF48686.1 - 0.0081 16.1 0.2 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 TMEM154 protein family DAG1 PF05454.11 OWF48686.1 - 0.015 14.7 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF753 PF05444.12 OWF48686.1 - 0.027 14.5 15.0 0.049 13.6 15.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF753) APH PF01636.23 OWF48686.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ODV-E18 PF10717.9 OWF48686.1 - 0.11 12.4 1.2 0.21 11.5 1.2 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 LtrA PF06772.11 OWF48686.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Toxin_TOLIP PF00087.21 OWF48686.1 - 2 8.7 17.3 4.7 7.5 17.3 1.6 1 0 0 1 1 1 0 Snake toxin and toxin-like protein SKG6 PF08693.10 OWF48686.1 - 4.5 6.8 10.3 8.5 5.9 10.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RhoGAP PF00620.27 OWF48687.1 - 5.7e-44 149.6 0.0 9.4e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 OWF48687.1 - 1.5e-14 53.6 7.5 2.7e-14 52.8 7.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 OWF48687.1 - 2e-12 47.0 0.0 6.1e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain zf-RING-like PF08746.11 OWF48687.1 - 0.065 13.5 2.1 0.15 12.4 2.1 1.6 1 0 0 1 1 1 0 RING-like domain FYVE_2 PF02318.16 OWF48687.1 - 0.065 13.4 0.5 0.15 12.3 0.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Dermcidin PF15291.6 OWF48687.1 - 0.24 12.0 0.6 0.81 10.3 0.1 2.0 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide zf-B_box PF00643.24 OWF48689.1 - 7.8e-13 48.4 18.3 4e-07 30.1 6.7 2.5 2 0 0 2 2 2 2 B-box zinc finger FAM184 PF15665.5 OWF48689.1 - 0.011 15.5 7.2 0.027 14.2 7.2 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF445 PF04286.12 OWF48689.1 - 0.023 14.5 2.1 0.028 14.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Fzo_mitofusin PF04799.13 OWF48689.1 - 0.35 10.4 8.0 1.1 8.7 8.0 1.8 1 1 0 1 1 1 0 fzo-like conserved region TPR_MLP1_2 PF07926.12 OWF48689.1 - 0.82 9.7 8.4 0.85 9.7 4.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Siva PF05458.12 OWF48689.1 - 0.88 9.2 9.6 0.94 9.1 0.6 2.4 2 0 0 2 2 2 0 Cd27 binding protein (Siva) IBR PF01485.21 OWF48689.1 - 1.4 9.2 20.2 0.22 11.8 5.8 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 OWF48689.1 - 6.3 6.9 14.4 0.89 9.6 4.0 2.6 2 0 0 2 2 2 0 zinc-ribbons Drf_FH1 PF06346.12 OWF48690.1 - 0.037 13.8 21.3 0.08 12.7 21.3 1.6 1 1 0 1 1 1 0 Formin Homology Region 1 TP2 PF01254.18 OWF48690.1 - 1.2 9.7 6.5 13 6.4 0.6 3.4 1 1 2 4 4 4 0 Nuclear transition protein 2 zf-B_box PF00643.24 OWF48691.1 - 4.3e-13 49.2 19.2 2.9e-07 30.5 6.7 2.7 2 0 0 2 2 2 2 B-box zinc finger ZZ PF00569.17 OWF48691.1 - 0.018 14.8 8.4 0.018 14.8 8.4 2.7 2 0 0 2 2 2 0 Zinc finger, ZZ type Siva PF05458.12 OWF48691.1 - 1.9 8.2 10.9 1.8 8.2 0.7 2.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) SAS4 PF15460.6 OWF48691.1 - 2.4 8.3 9.0 1.6 8.8 0.9 2.7 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 IBR PF01485.21 OWF48691.1 - 8.8 6.6 24.4 0.38 11.0 5.9 3.4 2 1 0 3 3 3 0 IBR domain, a half RING-finger domain Methyltransf_22 PF13383.6 OWF48692.1 - 5.3e-19 68.8 0.2 6.8e-19 68.4 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF48692.1 - 3.4e-07 30.5 0.0 5.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain GRAM PF02893.20 OWF48693.1 - 1.6e-19 69.9 0.1 3.2e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 GRAM domain MAM PF00629.23 OWF48695.1 - 3.2e-43 147.4 0.1 4.9e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Collagen PF01391.18 OWF48695.1 - 2.4e-18 65.6 68.5 3.1e-07 30.0 22.8 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) I-set PF07679.16 OWF48695.1 - 4.5e-09 36.3 0.0 4.5e-08 33.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF48695.1 - 1.7e-08 34.9 0.8 1e-07 32.4 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 OWF48695.1 - 2.1e-06 28.0 0.6 5.9e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Lectin_leg-like PF03388.13 OWF48697.1 - 2.8e-74 249.3 0.0 5.8e-74 248.3 0.0 1.5 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 OWF48697.1 - 2.9e-09 37.2 0.2 7.3e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial lectin HflK_N PF12221.8 OWF48697.1 - 0.089 12.8 1.8 0.78 9.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial membrane protein N terminal Tubulin_2 PF13809.6 OWF48697.1 - 0.11 11.7 1.1 0.23 10.6 1.1 1.6 1 1 0 1 1 1 0 Tubulin like Nsp1_C PF05064.13 OWF48697.1 - 0.89 9.4 6.6 0.56 10.0 0.5 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region DASH_Dad1 PF08649.10 OWF48697.1 - 0.9 9.8 3.2 0.56 10.4 0.5 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad1 Drf_FH1 PF06346.12 OWF48698.1 - 6e-11 42.3 12.8 1e-06 28.6 0.4 2.4 1 1 1 2 2 2 2 Formin Homology Region 1 PTR PF12789.7 OWF48698.1 - 0.0001 22.3 33.3 0.057 13.5 9.5 5.1 1 1 6 7 7 7 6 Phage tail repeat like Cuticle_3 PF11018.8 OWF48698.1 - 0.04 14.1 5.1 0.17 12.1 0.4 2.9 1 1 2 3 3 3 0 Pupal cuticle protein C1 E3_UbLigase_RBR PF18091.1 OWF48698.1 - 0.043 13.9 0.0 17 5.6 0.0 4.0 2 1 2 5 5 5 0 E3 Ubiquitin Ligase RBR C-terminal domain Ribosomal_L29 PF00831.23 OWF48698.1 - 0.054 13.5 0.1 0.2 11.6 0.1 2.0 1 0 0 1 1 1 0 Ribosomal L29 protein PROCN PF08083.11 OWF48699.1 - 3.7e-234 776.8 8.2 3.7e-234 776.8 8.2 1.5 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OWF48699.1 - 9.6e-130 431.1 0.9 1.6e-129 430.3 0.9 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OWF48699.1 - 1.8e-89 297.8 3.0 4e-89 296.6 2.4 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OWF48699.1 - 1.1e-84 281.9 5.7 1.1e-84 281.9 5.7 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OWF48699.1 - 6.6e-74 246.3 0.0 1.4e-73 245.3 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 OWF48699.1 - 8.2e-53 177.5 0.1 2.1e-52 176.2 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 OWF48699.1 - 8.5e-48 160.6 0.6 2.4e-47 159.2 0.6 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 OWF48699.1 - 3.4e-10 39.9 0.0 9.1e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease C1q PF00386.21 OWF48700.1 - 1.1e-24 87.1 3.1 1.7e-24 86.5 1.2 1.9 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF48700.1 - 7.5e-05 22.6 1.6 0.00011 22.1 1.6 1.2 1 0 0 1 1 1 1 BclA C-terminal domain CCDC74_C PF14917.6 OWF48700.1 - 0.096 13.2 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal CCDC92 PF14916.6 OWF48701.1 - 3.2e-19 68.5 0.9 1.4e-18 66.4 0.9 2.1 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Golgin_A5 PF09787.9 OWF48701.1 - 0.019 14.5 15.6 0.027 13.9 15.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Glutaredoxin2_C PF04399.13 OWF48701.1 - 0.16 11.8 3.3 0.16 11.8 0.4 2.2 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain UPF0242 PF06785.11 OWF48701.1 - 0.25 11.4 16.5 0.38 10.8 16.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 OWF48701.1 - 0.46 10.8 13.8 0.52 10.6 0.3 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 OWF48701.1 - 0.46 9.8 9.4 0.65 9.3 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RPW8 PF05659.11 OWF48701.1 - 0.49 10.1 9.4 2.1 8.0 4.5 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Seryl_tRNA_N PF02403.22 OWF48701.1 - 1.2 9.4 16.9 0.77 10.0 5.2 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 OWF48701.1 - 1.6 9.3 15.3 1.4 9.4 3.9 2.5 1 1 1 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 OWF48701.1 - 2.3 8.3 21.6 1.9 8.6 1.5 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding FliD_N PF02465.18 OWF48701.1 - 2.4 8.9 8.2 1.8 9.3 2.5 2.6 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PHM7_cyt PF14703.6 OWF48701.1 - 5 7.3 14.1 4.1 7.6 10.8 2.0 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Syntaxin-6_N PF09177.11 OWF48701.1 - 5.2 7.7 8.9 44 4.7 5.3 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KxDL PF10241.9 OWF48701.1 - 6.6 7.1 15.0 14 6.1 2.2 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein DTC PF18102.1 OWF48702.1 - 6.6e-52 175.2 0.0 1.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 OWF48702.1 - 2.4e-34 117.7 0.3 5.9e-16 58.8 0.0 2.4 2 0 0 2 2 2 2 WWE domain zf-rbx1 PF12678.7 OWF48702.1 - 0.00023 21.4 11.4 0.0004 20.6 11.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OWF48702.1 - 0.00052 19.8 14.0 0.00094 19.0 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF48702.1 - 0.0038 17.5 11.6 0.0082 16.5 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF48702.1 - 0.018 15.0 13.8 0.03 14.3 13.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF48702.1 - 0.03 14.4 4.2 0.069 13.2 4.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OWF48702.1 - 0.043 13.8 8.8 0.087 12.9 8.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 OWF48702.1 - 0.27 11.4 6.5 0.54 10.4 6.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Nse PF11789.8 OWF48702.1 - 1.1 9.1 6.8 2.7 7.9 6.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OWF48702.1 - 3.5 7.5 15.2 61 3.5 15.2 2.4 1 1 0 1 1 1 0 RING-like zinc finger SpoU_methylase PF00588.19 OWF48703.1 - 2.8e-25 89.1 0.0 4.8e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OWF48703.1 - 1.3e-15 57.4 0.0 6.9e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Sulfotransfer_2 PF03567.14 OWF48705.1 - 1.2e-27 97.4 5.0 1.3e-27 97.3 1.9 2.0 2 0 0 2 2 2 1 Sulfotransferase family MIP PF00230.20 OWF48706.1 - 4.2e-60 203.3 5.1 5e-60 203.0 5.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein Fis1_TPR_C PF14853.6 OWF48707.1 - 3.3e-05 23.9 0.1 7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat FAM176 PF14851.6 OWF48707.1 - 0.25 11.0 14.0 0.17 11.6 1.5 2.7 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.10 OWF48707.1 - 2.6 7.3 31.1 1.3 8.3 28.9 1.4 1 1 0 1 1 1 0 BUD22 TLP-20 PF06088.11 OWF48707.1 - 2.7 7.9 13.1 1 9.2 2.8 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cwf_Cwc_15 PF04889.12 OWF48707.1 - 9 5.9 38.5 1.1 8.9 14.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C3Hc3H PF13891.6 OWF48708.1 - 1.6e-26 92.4 27.8 7.5e-15 55.0 7.9 2.6 2 0 0 2 2 2 2 Potential DNA-binding domain zf-primase PF09329.11 OWF48708.1 - 0.27 11.1 4.1 4.9 7.0 0.2 2.6 2 0 0 2 2 2 0 Primase zinc finger Tropomyosin PF00261.20 OWF48709.1 - 0.004 16.6 20.5 0.004 16.6 20.5 6.0 5 2 0 5 5 5 2 Tropomyosin G2F PF07474.12 OWF48710.1 - 2.4e-58 197.0 0.1 4e-58 196.2 0.1 1.4 1 0 0 1 1 1 1 G2F domain EGF_3 PF12947.7 OWF48710.1 - 6.3e-53 176.7 187.0 2.4e-09 37.3 7.2 12.4 12 0 0 12 12 12 11 EGF domain Ldl_recept_b PF00058.17 OWF48710.1 - 2.5e-35 120.7 7.7 3e-11 43.6 0.1 5.6 6 0 0 6 6 5 3 Low-density lipoprotein receptor repeat class B EGF PF00008.27 OWF48710.1 - 9.8e-24 83.3 164.3 0.00022 21.4 7.9 12.7 12 0 0 12 12 12 10 EGF-like domain cEGF PF12662.7 OWF48710.1 - 1.2e-23 82.6 118.1 8.9e-08 31.9 4.5 11.6 11 0 0 11 11 11 9 Complement Clr-like EGF-like NIDO PF06119.14 OWF48710.1 - 1.1e-22 80.8 0.0 3.2e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 Nidogen-like EGF_MSP1_1 PF12946.7 OWF48710.1 - 1.2e-13 50.8 132.0 0.00037 20.5 7.1 10.8 10 0 0 10 10 10 8 MSP1 EGF domain 1 EGF_CA PF07645.15 OWF48710.1 - 1.2e-09 38.2 23.6 3.7e-09 36.6 7.8 12.4 12 1 0 12 12 11 5 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF48710.1 - 1.7e-06 28.2 6.1 1.7e-06 28.2 6.1 12.5 9 3 3 12 12 11 3 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 OWF48710.1 - 0.00035 20.8 2.6 0.00035 20.8 2.6 10.7 11 0 0 11 11 10 5 Pvs28 EGF domain hEGF PF12661.7 OWF48710.1 - 0.00097 19.7 4.4 0.00097 19.7 4.4 13.7 14 1 0 14 14 12 7 Human growth factor-like EGF SGL PF08450.12 OWF48710.1 - 0.0011 18.6 2.2 0.032 13.8 2.2 3.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region LRR_6 PF13516.6 OWF48711.1 - 6e-11 41.5 2.3 0.042 13.9 0.0 6.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 OWF48711.1 - 0.16 12.6 3.5 83 4.4 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat tRNA-synt_1b PF00579.25 OWF48712.1 - 2.6e-24 86.1 0.0 7.3e-24 84.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4287 PF14117.6 OWF48712.1 - 0.069 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Invas_SpaK PF03519.14 OWF48712.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Invasion protein B family WD40 PF00400.32 OWF48713.1 - 1.4e-17 63.7 17.3 0.0017 19.2 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF48713.1 - 4.4e-06 26.9 0.1 1.3 9.4 0.2 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 OWF48714.1 - 4.8e-39 133.8 0.0 1.1e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF48714.1 - 3.5e-08 33.1 0.8 5.3e-08 32.6 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 OWF48714.1 - 2.6e-06 27.3 0.1 8.8e-06 25.5 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain MIT PF04212.18 OWF48714.1 - 6.1e-05 23.0 0.1 0.00014 21.8 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 OWF48714.1 - 6.3e-05 22.9 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 OWF48714.1 - 9.2e-05 22.7 0.2 0.018 15.3 0.0 3.2 1 1 2 3 3 3 1 AAA domain TniB PF05621.11 OWF48714.1 - 0.00035 20.0 0.2 0.46 9.9 0.0 3.4 2 1 1 3 3 3 1 Bacterial TniB protein AAA_5 PF07728.14 OWF48714.1 - 0.00038 20.5 0.1 0.0031 17.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OWF48714.1 - 0.00043 19.6 0.0 0.00074 18.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OWF48714.1 - 0.0016 18.6 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OWF48714.1 - 0.0019 17.6 0.3 0.011 15.2 0.3 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 OWF48714.1 - 0.012 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OWF48714.1 - 0.013 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Bac_DnaA PF00308.18 OWF48714.1 - 0.033 14.0 0.0 0.097 12.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_14 PF13173.6 OWF48714.1 - 0.036 14.1 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF48714.1 - 0.037 14.4 0.1 0.13 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain TPR_1 PF00515.28 OWF48714.1 - 0.066 13.1 1.5 6.1 6.8 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat RNA_helicase PF00910.22 OWF48714.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OWF48714.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 OWF48714.1 - 0.18 12.1 2.0 16 6.0 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF908 PF06012.12 OWF48714.1 - 2.4 7.5 6.6 3.2 7.1 4.7 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) SOCS_box PF07525.16 OWF48715.1 - 1.3e-07 31.9 0.8 2.6e-07 30.9 0.8 1.6 1 0 0 1 1 1 1 SOCS box Pkinase PF00069.25 OWF48715.1 - 2.5e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Rossmann-like PF10727.9 OWF48716.1 - 9.7 6.1 19.6 36 4.2 1.5 4.1 1 1 3 4 4 4 0 Rossmann-like domain Arginase PF00491.21 OWF48718.1 - 2e-72 244.0 0.1 2.3e-72 243.8 0.1 1.0 1 0 0 1 1 1 1 Arginase family EB PF01683.18 OWF48719.1 - 0.16 12.3 0.7 18 5.7 0.7 3.3 1 1 0 1 1 1 0 EB module DUF1441 PF07278.11 OWF48719.1 - 0.2 11.6 0.0 2.6 8.0 0.0 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1441) TMEM125 PF15109.6 OWF48720.1 - 0.12 12.8 11.5 5.4 7.4 2.7 4.1 1 1 2 3 3 3 0 TMEM125 protein family Antimicrobial_8 PF08103.11 OWF48720.1 - 0.29 11.4 16.3 21 5.5 0.4 7.4 8 2 2 10 10 10 0 Uperin family BAAT_C PF08840.11 OWF48720.1 - 0.44 10.4 3.4 1.1 9.2 1.5 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FANCI_HD1 PF14679.6 OWF48720.1 - 0.67 9.9 8.8 3.2 7.8 0.6 3.5 1 1 2 3 3 3 0 FANCI helical domain 1 TEX29 PF15839.5 OWF48720.1 - 1 10.0 19.5 9.6e+02 0.5 0.1 4.2 1 1 1 2 2 2 0 Testis-expressed sequence 29 protein DUF1071 PF06378.11 OWF48720.1 - 4.5 6.8 6.8 24 4.5 4.4 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1071) NADH5_C PF06455.11 OWF48720.1 - 6.3 6.3 20.6 20 4.7 5.5 3.2 1 1 2 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus Virulence_RhuM PF13310.6 OWF48721.1 - 0.0067 15.7 0.7 0.015 14.5 0.7 1.6 1 0 0 1 1 1 1 Virulence protein RhuM family Glyco_trans_4_3 PF12000.8 OWF48721.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 4 group CdiI_2 PF18593.1 OWF48721.1 - 0.15 12.7 1.9 0.32 11.7 0.8 2.1 1 1 1 2 2 2 0 CdiI immunity protein Phlebovirus_NSM PF07246.11 OWF48721.1 - 0.27 10.6 7.7 0.67 9.3 7.5 1.6 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3450 PF11932.8 OWF48721.1 - 0.77 9.0 13.5 0.14 11.5 3.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 OWF48721.1 - 0.86 9.7 20.6 0.77 9.8 5.6 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus KinB_sensor PF16767.5 OWF48721.1 - 2.9 8.4 8.3 7.1 7.1 1.2 2.7 1 1 1 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Il2rg PF15874.5 OWF48722.1 - 1.3e-22 79.9 0.1 1.9e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain DUF5350 PF17299.2 OWF48722.1 - 0.084 13.4 1.9 0.28 11.7 2.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5350) AMPK1_CBM PF16561.5 OWF48723.1 - 1.8e-34 117.8 0.9 2.8e-34 117.2 0.5 1.5 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 OWF48723.1 - 2.4e-18 66.2 1.6 2.4e-18 66.2 1.6 1.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 OWF48723.1 - 0.037 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ras PF00071.22 OWF48724.1 - 3.5e-43 147.0 0.0 4.1e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF48724.1 - 4.9e-19 68.7 0.0 7e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OWF48724.1 - 1.2e-05 24.9 0.1 0.00028 20.5 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF48724.1 - 2.4e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OWF48724.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF48724.1 - 0.0022 17.9 0.3 0.038 13.9 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OWF48724.1 - 0.0066 16.7 0.0 0.11 12.7 0.0 2.5 2 1 1 3 3 3 1 AAA domain PduV-EutP PF10662.9 OWF48724.1 - 0.0068 16.2 0.1 0.31 10.8 0.1 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OWF48724.1 - 0.01 16.2 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OWF48724.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OWF48724.1 - 0.035 14.1 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OWF48724.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OWF48724.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OWF48724.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain GTP_EFTU PF00009.27 OWF48725.1 - 3.3e-59 199.7 0.1 5.7e-59 198.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OWF48725.1 - 2.5e-30 104.4 0.4 9.3e-29 99.4 0.1 2.7 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 OWF48725.1 - 1.6e-18 66.5 0.0 3.6e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 OWF48725.1 - 3.4e-10 39.7 0.0 6.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 OWF48725.1 - 6.7e-09 35.7 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 OWF48725.1 - 0.00015 22.1 0.0 0.00041 20.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF48725.1 - 0.00019 21.5 0.0 0.00052 20.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF48725.1 - 0.022 14.3 0.0 0.065 12.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Ank_4 PF13637.6 OWF48726.1 - 0.00013 22.4 0.3 1.2 9.8 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF48726.1 - 0.00045 20.7 0.0 0.0016 19.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OWF48727.1 - 2.6e-09 37.5 3.4 0.0043 17.6 0.2 4.9 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) UvrD_C_2 PF13538.6 OWF48727.1 - 1.3e-06 28.1 0.0 0.01 15.6 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Ank_4 PF13637.6 OWF48727.1 - 3.2e-06 27.6 1.2 1.8 9.3 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) AAA_19 PF13245.6 OWF48727.1 - 3.9e-05 24.0 0.7 0.016 15.5 0.2 3.4 3 0 0 3 3 2 1 AAA domain Ank_5 PF13857.6 OWF48727.1 - 0.00058 20.1 0.3 0.4 11.1 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 OWF48727.1 - 0.015 15.6 0.0 0.92 9.8 0.0 3.3 2 0 0 2 2 2 0 AAA domain Ank PF00023.30 OWF48727.1 - 0.031 14.7 1.9 0.6 10.7 0.0 3.7 4 0 0 4 4 3 0 Ankyrin repeat Clathrin PF00637.20 OWF48727.1 - 0.06 13.2 8.1 0.11 12.4 1.2 3.9 2 1 0 2 2 2 0 Region in Clathrin and VPS Ank_3 PF13606.6 OWF48727.1 - 0.096 13.3 1.0 18 6.3 0.0 4.5 5 0 0 5 5 4 0 Ankyrin repeat TPR_7 PF13176.6 OWF48727.1 - 0.25 11.5 4.4 30 4.9 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Clr5 PF14420.6 OWF48727.1 - 0.31 11.3 1.4 2.4 8.4 1.6 2.6 2 0 0 2 2 2 0 Clr5 domain ANAPC3 PF12895.7 OWF48727.1 - 0.72 10.1 6.2 20 5.5 0.3 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OWF48727.1 - 1.4 8.6 7.9 20 5.0 0.0 4.7 5 0 0 5 5 5 0 TPR repeat PPR PF01535.20 OWF48727.1 - 4.5 7.7 5.2 5.5 7.5 0.9 3.5 4 0 0 4 4 4 0 PPR repeat Lectin_C PF00059.21 OWF48728.1 - 1.3e-10 41.9 0.9 2.2e-10 41.2 0.9 1.4 1 0 0 1 1 1 1 Lectin C-type domain Takusan PF04822.13 OWF48728.1 - 0.09 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Takusan DUF2140 PF09911.9 OWF48729.1 - 0.0027 17.3 1.6 0.0036 16.9 1.1 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) ABC2_membrane_3 PF12698.7 OWF48729.1 - 0.18 10.9 0.0 0.19 10.8 0.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein O-antigen_lig PF13425.6 OWF48729.1 - 0.22 10.3 4.8 0.27 10.0 4.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein OSTbeta PF15048.6 OWF48729.1 - 0.29 11.3 6.1 0.2 11.8 4.6 1.5 1 1 1 2 2 2 0 Organic solute transporter subunit beta protein FAM195 PF14799.6 OWF48729.1 - 0.35 11.2 6.1 0.48 10.8 6.1 1.2 1 0 0 1 1 1 0 FAM195 family ETRAMP PF09716.10 OWF48729.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ureide_permease PF07168.11 OWF48729.1 - 0.6 8.8 3.4 0.72 8.5 3.4 1.1 1 0 0 1 1 1 0 Ureide permease SID-1_RNA_chan PF13965.6 OWF48729.1 - 0.89 7.9 4.1 0.97 7.8 4.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 OWF48729.1 - 1 9.4 7.6 1.4 9.0 7.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GRP PF07172.11 OWF48729.1 - 1.9 9.3 4.3 5.1 7.8 4.3 1.9 1 1 0 1 1 1 0 Glycine rich protein family Gal-3-0_sulfotr PF06990.11 OWF48730.1 - 3.3e-44 151.4 1.3 4.4e-44 151.0 1.3 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase PKD PF00801.20 OWF48731.1 - 0.00067 19.5 3.6 2.2 8.2 0.0 4.5 5 0 0 5 5 5 2 PKD domain Amino_oxidase PF01593.24 OWF48732.1 - 2.5e-49 168.8 0.0 6e-48 164.3 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF48732.1 - 1.7e-09 37.7 0.0 4.5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF48732.1 - 5.1e-07 29.6 1.5 0.00045 19.9 0.4 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OWF48732.1 - 9.4e-07 28.3 0.2 1.5e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OWF48732.1 - 1.5e-06 28.3 0.6 0.0087 16.1 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OWF48732.1 - 1.4e-05 24.3 0.3 2.5e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF48732.1 - 0.00012 21.0 0.6 0.013 14.2 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OWF48732.1 - 0.00015 21.2 0.1 0.0003 20.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF48732.1 - 0.00021 20.6 0.0 0.043 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF48732.1 - 0.00034 20.0 0.2 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF48732.1 - 0.00067 18.8 0.5 0.0077 15.3 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OWF48732.1 - 0.0071 16.9 1.0 0.014 15.9 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OWF48732.1 - 0.02 14.2 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OWF48732.1 - 0.031 13.4 0.9 0.39 9.7 0.2 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Chordopox_A33R PF05966.12 OWF48732.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Cadherin PF00028.17 OWF48733.1 - 5.1e-141 459.5 48.1 3.9e-17 62.5 0.3 14.4 14 0 0 14 14 14 14 Cadherin domain Cadherin_3 PF16184.5 OWF48733.1 - 2.8e-14 53.0 33.7 0.027 14.5 0.0 11.6 11 1 1 12 12 12 5 Cadherin-like Cadherin_2 PF08266.12 OWF48733.1 - 6.9e-11 41.8 1.4 0.0011 18.7 0.1 7.3 9 0 0 9 9 9 2 Cadherin-like Y_Y_Y PF07495.13 OWF48733.1 - 2e-05 24.4 5.5 0.28 11.1 0.0 6.7 7 0 0 7 7 7 1 Y_Y_Y domain RET_CLD1 PF17756.1 OWF48733.1 - 0.00012 22.4 0.0 0.54 10.6 0.0 5.3 5 1 0 5 5 5 1 RET Cadherin like domain 1 Shisa PF13908.6 OWF48733.1 - 0.0086 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Comm PF15957.5 OWF48733.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Commissureless Cadherin PF00028.17 OWF48734.1 - 7.8e-133 433.3 51.0 2.5e-18 66.3 0.4 15.1 14 2 0 14 14 14 14 Cadherin domain Cadherin_3 PF16184.5 OWF48734.1 - 1.5e-11 44.2 27.1 0.11 12.5 0.0 9.9 10 0 0 10 10 10 5 Cadherin-like Cadherin_2 PF08266.12 OWF48734.1 - 0.00085 19.1 0.0 18 5.2 0.0 6.4 7 1 0 7 7 7 1 Cadherin-like RET_CLD1 PF17756.1 OWF48734.1 - 0.0016 18.8 0.0 3.1 8.1 0.0 4.4 5 0 0 5 5 5 1 RET Cadherin like domain 1 SNN_transmemb PF09049.10 OWF48734.1 - 0.84 9.6 4.5 4.4 7.3 0.0 3.8 3 0 0 3 3 3 0 Stannin transmembrane Cadherin PF00028.17 OWF48736.1 - 1.7e-167 544.4 37.5 5.1e-20 71.7 0.1 14.7 14 1 0 14 14 14 14 Cadherin domain Cadherin_2 PF08266.12 OWF48736.1 - 9.4e-25 86.3 0.3 0.46 10.3 0.0 10.9 10 0 0 10 10 10 8 Cadherin-like Cadherin_3 PF16184.5 OWF48736.1 - 1.7e-16 60.2 33.5 0.13 12.2 0.2 13.1 14 0 0 14 14 14 7 Cadherin-like RET_CLD1 PF17756.1 OWF48736.1 - 7.7e-12 45.6 0.0 0.0086 16.4 0.0 7.2 8 0 0 8 8 8 3 RET Cadherin like domain 1 TMEM154 PF15102.6 OWF48736.1 - 0.0069 16.3 0.2 0.024 14.6 0.2 1.9 1 0 0 1 1 1 1 TMEM154 protein family MucB_RseB PF03888.14 OWF48736.1 - 0.025 14.1 0.1 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 MucB/RseB N-terminal domain EptA_B_N PF08019.12 OWF48736.1 - 0.085 12.7 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB Invasin_D3 PF09134.10 OWF48736.1 - 0.13 12.5 23.4 3 8.2 0.2 8.0 7 1 0 7 7 7 0 Invasin, domain 3 Y_Y_Y PF07495.13 OWF48736.1 - 0.22 11.5 1.8 15 5.6 0.1 4.4 3 0 0 3 3 3 0 Y_Y_Y domain DUF5011 PF16403.5 OWF48736.1 - 0.27 11.4 3.1 8.1 6.7 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) Cadherin_4 PF17803.1 OWF48736.1 - 0.51 11.0 70.2 0.29 11.8 1.5 11.5 11 0 0 11 11 11 0 Bacterial cadherin-like domain PNP_phzG_C PF10590.9 OWF48737.1 - 0.00051 20.1 2.1 29 4.8 2.1 6.1 1 1 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pox_F17 PF04767.12 OWF48737.1 - 0.63 10.6 25.9 7.2 7.2 0.6 4.8 1 1 3 4 4 4 0 DNA-binding 11 kDa phosphoprotein SRCR PF00530.18 OWF48738.1 - 0.058 13.9 2.9 0.069 13.7 0.6 2.2 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain SelK_SelG PF10961.8 OWF48738.1 - 1.2 9.8 4.2 2.8 8.6 0.2 3.5 3 1 0 3 3 3 0 Selenoprotein SelK_SelG SET PF00856.28 OWF48739.1 - 0.024 15.0 5.6 0.29 11.5 5.3 3.4 1 1 0 1 1 1 0 SET domain PSI_integrin PF17205.3 OWF48739.1 - 0.092 12.5 0.6 0.27 11.0 0.6 1.7 1 0 0 1 1 1 0 Integrin plexin domain FAM176 PF14851.6 OWF48739.1 - 0.23 11.1 0.0 0.23 11.1 0.0 3.4 3 1 1 4 4 4 0 FAM176 family p450 PF00067.22 OWF48740.1 - 6.7e-35 120.7 0.8 7.6e-27 94.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Rif1_N PF12231.8 OWF48740.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal DASH_Spc19 PF08287.11 OWF48741.1 - 0.0044 16.9 8.8 0.01 15.8 8.8 1.6 1 0 0 1 1 1 1 Spc19 COG5 PF10392.9 OWF48741.1 - 0.057 13.6 5.4 0.13 12.4 4.7 2.0 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Sec34 PF04136.15 OWF48741.1 - 0.14 12.0 7.2 0.37 10.7 6.2 2.1 1 1 1 2 2 2 0 Sec34-like family Nuf2 PF03800.14 OWF48741.1 - 0.17 12.0 4.0 0.92 9.6 3.4 2.3 2 1 0 2 2 2 0 Nuf2 family Gp-FAR-1 PF05823.12 OWF48741.1 - 0.18 12.1 10.2 0.079 13.3 7.1 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SieB PF14163.6 OWF48741.1 - 0.23 10.9 3.4 0.46 10.0 3.4 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B SPRR2 PF14820.6 OWF48742.1 - 0.34 11.0 11.1 5.6 7.1 0.1 2.3 1 1 1 2 2 2 0 Small proline-rich 2 SfsA_N PF17746.1 OWF48742.1 - 0.56 10.4 6.6 7.9 6.7 2.8 3.3 1 1 1 2 2 2 0 SfsA N-terminal OB domain FGF-BP1 PF06473.12 OWF48742.1 - 1.9 8.3 6.3 9.3 6.0 0.3 2.4 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) Peptidase_M99_m PF17130.4 OWF48743.1 - 3.3 7.7 5.0 37 4.3 2.5 2.4 1 1 1 2 2 2 0 beta-barrel domain of carboxypeptidase M99 zf-Mss51 PF13824.6 OWF48743.1 - 3.7 7.7 12.4 13 6.0 0.5 3.6 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 RNA_pol_N PF01194.17 OWF48743.1 - 4.6 7.6 7.4 18 5.7 0.5 3.1 1 1 1 2 2 2 0 RNA polymerases N / 8 kDa subunit Sulfotransfer_2 PF03567.14 OWF48744.1 - 9.8e-55 186.2 2.8 1.3e-54 185.8 2.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family Apo-CIII PF05778.12 OWF48745.1 - 6.2e-05 22.5 0.4 10 5.8 0.0 4.5 1 1 4 5 5 5 3 Apolipoprotein CIII (Apo-CIII) Halo_GVPC PF05465.13 OWF48745.1 - 0.0002 21.5 1.7 24 5.3 0.0 5.5 2 1 5 7 7 7 0 Halobacterial gas vesicle protein C (GVPC) repeat PMEI PF04043.15 OWF48745.1 - 0.00042 20.7 0.0 0.025 14.9 0.0 2.1 1 1 1 2 2 2 2 Plant invertase/pectin methylesterase inhibitor UPF0444 PF15475.6 OWF48745.1 - 0.0014 18.9 4.3 8.8 6.7 1.1 4.3 1 1 2 3 3 3 1 Transmembrane protein C12orf23, UPF0444 HBM PF16591.5 OWF48745.1 - 0.013 15.0 0.0 5.4 6.4 0.0 3.1 1 1 2 3 3 3 0 Helical bimodular sensor domain DASH_Spc19 PF08287.11 OWF48745.1 - 0.043 13.7 0.0 16 5.3 0.0 2.9 1 1 3 4 4 4 0 Spc19 DUF2618 PF10940.8 OWF48745.1 - 0.24 11.2 2.4 1 9.2 2.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2618) LPD7 PF18821.1 OWF48745.1 - 0.49 10.6 3.7 1.6e+02 2.5 3.7 3.9 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 7 AAA_12 PF13087.6 OWF48746.1 - 3.7e-47 160.5 0.1 5.2e-45 153.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 OWF48746.1 - 1.8e-30 106.6 0.8 3.5e-15 56.5 0.1 3.1 3 0 0 3 3 3 2 AAA domain S1-like PF14444.6 OWF48746.1 - 2.3e-19 69.0 15.4 1.1e-08 34.8 0.1 4.8 5 0 0 5 5 5 3 S1-like AAA_30 PF13604.6 OWF48746.1 - 2.7e-12 46.8 0.0 4.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF48746.1 - 5.3e-10 39.8 0.0 2e-09 37.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 OWF48746.1 - 1.7e-06 27.8 0.0 9.1e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 OWF48746.1 - 0.00011 21.7 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 OWF48746.1 - 0.00012 22.1 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OWF48746.1 - 0.0018 18.3 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UvrD_C PF13361.6 OWF48746.1 - 0.021 14.2 0.0 0.45 9.8 0.0 2.8 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 OWF48746.1 - 0.029 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 OWF48746.1 - 0.042 14.3 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 OWF48746.1 - 0.1 11.8 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_7 PF12775.7 OWF48746.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OWF48746.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain IBR PF01485.21 OWF48747.1 - 7.8e-19 67.7 29.9 2.6e-14 53.2 4.4 4.1 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OWF48747.1 - 0.00016 21.6 13.7 0.00016 21.6 13.7 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF48747.1 - 0.021 15.1 12.8 0.021 15.1 12.8 4.0 3 0 0 3 3 3 0 Ring finger domain PROCT PF08084.11 OWF48747.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain SHIPPO-rpt PF07004.12 OWF48748.1 - 1.3e-12 48.0 70.5 2e-05 25.3 0.3 10.8 10 2 0 10 10 10 7 Sperm-tail PG-rich repeat Exo_endo_phos PF03372.23 OWF48749.1 - 1e-13 51.4 0.0 2.4e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TMEM132D_N PF15705.5 OWF48749.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Exo_endo_phos_2 PF14529.6 OWF48749.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Prp18 PF02840.15 OWF48750.1 - 7.6e-61 204.4 0.1 7.6e-61 204.4 0.1 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 OWF48750.1 - 2.8e-12 46.0 1.7 5.9e-12 44.9 1.7 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like bZIP_2 PF07716.15 OWF48751.1 - 1.5e-11 44.2 15.3 1.8e-11 43.9 9.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF48751.1 - 0.00018 21.5 10.5 0.00021 21.3 5.9 2.4 2 0 0 2 2 2 1 bZIP transcription factor Mto2_bdg PF12808.7 OWF48751.1 - 0.013 15.7 1.2 0.04 14.2 1.2 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.18 OWF48751.1 - 0.35 11.1 0.2 0.35 11.1 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper SH3_3 PF08239.11 OWF48752.1 - 0.23 11.7 0.4 1.1 9.6 0.4 2.0 1 1 0 1 1 1 0 Bacterial SH3 domain Sugar_tr PF00083.24 OWF48753.1 - 9e-39 133.6 14.5 2e-29 102.8 6.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OWF48753.1 - 1e-06 27.9 15.1 0.0021 17.1 3.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI_integrin PF17205.3 OWF48753.1 - 0.97 9.2 9.8 0.18 11.6 6.1 1.7 2 0 0 2 2 2 0 Integrin plexin domain Sugar_tr PF00083.24 OWF48754.1 - 1.2e-35 123.3 13.0 1.4e-35 123.0 13.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF48754.1 - 4.7e-18 65.2 15.0 5.5e-18 65.0 15.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF48754.1 - 0.0043 16.0 3.9 0.0046 15.9 3.9 1.0 1 0 0 1 1 1 1 MFS_1 like family Carn_acyltransf PF00755.20 OWF48755.1 - 2.3e-186 620.9 0.0 2.6e-186 620.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Trypsin PF00089.26 OWF48756.1 - 3.3e-19 69.6 0.4 3.9e-19 69.3 0.4 1.0 1 0 0 1 1 1 1 Trypsin UQ_con PF00179.26 OWF48757.1 - 1e-47 161.3 0.0 1.2e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF48757.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OWF48757.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OWF48757.1 - 0.027 14.7 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Aminotran_1_2 PF00155.21 OWF48758.1 - 3.8e-77 259.9 0.0 4.7e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.10 OWF48758.1 - 2.8e-09 37.5 3.1 1.7e-07 31.8 1.4 2.8 1 1 1 2 2 2 1 5-aminolevulinate synthase presequence Aminotran_5 PF00266.19 OWF48758.1 - 1.2e-06 27.7 0.0 7.1e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OWF48758.1 - 2e-05 23.3 0.0 3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OWF48758.1 - 0.0021 17.5 0.1 0.0041 16.5 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AAA_13 PF13166.6 OWF48758.1 - 0.0082 14.9 0.1 0.016 13.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.21 OWF48758.1 - 0.11 11.1 0.1 0.22 10.1 0.1 1.5 1 1 0 1 1 1 0 Aminotransferase class-III Laminin_EGF PF00053.24 OWF48759.1 - 7.6e-102 333.3 275.9 7.4e-10 38.8 14.2 14.6 14 0 0 14 14 14 13 Laminin EGF domain Laminin_N PF00055.17 OWF48759.1 - 1.1e-74 251.0 0.2 4.6e-74 249.0 0.2 2.2 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) F5_F8_type_C PF00754.25 OWF48759.1 - 8.9e-06 25.8 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain BNR_6 PF15899.5 OWF48759.1 - 0.076 13.1 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 BNR-Asp box repeat Rx_N PF18052.1 OWF48759.1 - 0.78 10.1 9.6 1.7 8.9 0.6 3.4 2 1 0 2 2 2 0 Rx N-terminal domain Fib_alpha PF08702.10 OWF48759.1 - 3.9 7.7 45.1 0.2 11.8 3.6 4.9 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 OWF48760.1 - 2.3e-56 191.1 0.0 3.6e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF48760.1 - 7.7e-44 149.9 0.0 1.1e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF48760.1 - 0.0031 16.3 0.0 0.0059 15.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OWF48760.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like WBP-1 PF11669.8 OWF48761.1 - 0.0012 19.5 0.6 0.0017 18.9 0.6 1.2 1 0 0 1 1 1 1 WW domain-binding protein 1 RCR PF12273.8 OWF48761.1 - 0.013 16.1 0.1 0.021 15.5 0.1 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SCIMP PF15050.6 OWF48761.1 - 0.041 14.3 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein SKN1 PF03935.15 OWF48761.1 - 0.057 11.8 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Actin PF00022.19 OWF48762.1 - 2.4e-144 480.9 0.0 8.2e-144 479.2 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 OWF48763.1 - 2e-126 421.9 0.0 7.3e-126 420.1 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 OWF48764.1 - 6.2e-131 436.8 0.0 2.4e-130 434.8 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 OWF48765.1 - 1.8e-117 392.4 0.0 7.6e-116 387.1 0.0 2.0 1 1 0 1 1 1 1 Actin Actin PF00022.19 OWF48766.1 - 9.3e-143 475.7 0.0 3.5e-142 473.8 0.0 1.7 1 1 0 1 1 1 1 Actin WASH-7_N PF14745.6 OWF48767.1 - 2.8e-239 795.4 13.4 9.4e-239 793.7 9.7 2.1 2 0 0 2 2 2 2 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 OWF48767.1 - 1.6e-169 563.5 7.6 1.6e-169 563.5 7.6 1.8 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_C PF14746.6 OWF48767.1 - 1.1e-73 246.6 0.2 3.3e-73 245.1 0.2 1.9 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Stap_Strp_tox_C PF02876.17 OWF48767.1 - 0.003 17.8 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 Staphylococcal/Streptococcal toxin, beta-grasp domain DUF3586 PF12131.8 OWF48767.1 - 0.94 9.7 4.5 2.5 8.4 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Ig_3 PF13927.6 OWF48768.1 - 5.6e-66 219.1 1.2 4.1e-12 46.5 0.1 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 OWF48768.1 - 8.6e-52 173.2 0.0 6.2e-09 35.8 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF48768.1 - 1.2e-45 153.8 2.0 1.1e-10 41.7 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 OWF48768.1 - 1.5e-41 140.5 1.5 2.2e-06 27.8 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 OWF48768.1 - 9.3e-27 93.2 9.1 1.9e-08 34.5 0.1 5.1 5 0 0 5 5 5 4 Fibronectin type III domain V-set PF07686.17 OWF48768.1 - 1.1e-18 67.3 11.5 5e-05 23.4 0.0 8.3 6 3 1 7 7 7 5 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF48768.1 - 1.5e-12 46.8 1.1 0.37 10.4 0.0 7.0 7 0 0 7 7 7 3 Immunoglobulin domain Ig_5 PF16681.5 OWF48768.1 - 3.8e-08 33.6 0.0 0.37 11.2 0.0 5.9 6 1 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain UL45 PF05473.12 OWF48768.1 - 1.1e-07 31.7 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Ig_C17orf99 PF17736.1 OWF48768.1 - 5.7e-07 29.5 0.0 0.42 10.7 0.0 4.9 5 0 0 5 5 5 2 C17orf99 Ig domain Izumo-Ig PF16706.5 OWF48768.1 - 2.4e-06 27.5 2.7 2.7 8.1 0.0 6.2 7 0 0 7 7 6 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 OWF48768.1 - 7.8e-06 26.1 0.3 2.5 8.4 0.0 6.1 6 1 0 6 6 6 1 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 OWF48768.1 - 3.2e-05 24.4 2.9 0.43 11.2 0.0 3.7 4 0 0 4 4 3 2 Purple acid Phosphatase, N-terminal domain Lectin_C PF00059.21 OWF48768.1 - 0.00012 22.7 0.0 0.00031 21.4 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain V-set_CD47 PF08204.11 OWF48768.1 - 0.00017 21.5 0.2 12 5.9 0.0 5.1 3 1 1 4 4 4 0 CD47 immunoglobulin-like domain DUF2369 PF10179.9 OWF48768.1 - 0.0012 19.2 0.1 1.7 9.1 0.1 2.9 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) Receptor_2B4 PF11465.8 OWF48768.1 - 0.0016 18.7 0.7 8.4 6.6 0.0 5.0 5 1 1 6 6 5 1 Natural killer cell receptor 2B4 C2-set PF05790.15 OWF48768.1 - 0.1 12.8 0.0 44 4.4 0.0 4.0 4 1 0 4 4 4 0 Immunoglobulin C2-set domain Pkinase PF00069.25 OWF48769.1 - 1.5e-68 231.0 0.0 1.8e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF48769.1 - 8.6e-33 113.7 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF48769.1 - 2.5e-06 27.0 0.2 3.9e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF48769.1 - 0.0026 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OWF48769.1 - 0.0039 17.1 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OWF48769.1 - 0.0073 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OWF48769.1 - 0.0095 14.9 0.2 0.014 14.3 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OWF48769.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Arf PF00025.21 OWF48770.1 - 1.8e-49 167.6 0.0 2e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OWF48770.1 - 1e-12 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OWF48770.1 - 9.7e-12 44.7 2.0 7.7e-07 28.6 0.3 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OWF48770.1 - 1.2e-11 44.9 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OWF48770.1 - 4.4e-10 39.3 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF48770.1 - 1.1e-09 38.0 0.1 1.4e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF48770.1 - 6.6e-07 29.1 0.1 0.00027 20.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF48770.1 - 6.9e-07 29.3 0.0 9.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 OWF48770.1 - 0.0039 17.7 0.0 0.0061 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OWF48770.1 - 0.0077 16.1 0.0 0.85 9.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OWF48770.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 OWF48770.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 OWF48770.1 - 0.037 13.8 0.0 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OWF48770.1 - 0.051 13.9 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OWF48770.1 - 0.087 12.2 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.18 OWF48770.1 - 0.12 11.9 0.1 0.33 10.4 0.0 1.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 OWF48770.1 - 0.13 12.3 0.0 6.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Dynamin family T4_tail_cap PF11091.8 OWF48770.1 - 0.15 10.9 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Tail-tube assembly protein Bromo_TP PF07524.13 OWF48771.1 - 1.4e-17 63.4 0.0 2.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 OWF48771.1 - 1.6e-10 40.7 8.8 3.1e-10 39.8 8.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OWF48771.1 - 7.5e-05 22.2 4.7 7.5e-05 22.2 4.7 2.2 2 0 0 2 2 2 1 PHD-finger ANF_receptor PF01094.28 OWF48772.1 - 9.5e-56 189.4 1.7 5.1e-36 124.5 0.3 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF48772.1 - 1.4e-10 41.4 0.2 8.6e-10 38.8 0.0 2.3 3 0 0 3 3 3 1 Periplasmic binding protein EphA2_TM PF14575.6 OWF48772.1 - 0.092 13.6 0.0 0.26 12.2 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 OWF48772.1 - 0.092 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF4692 PF15763.5 OWF48772.1 - 0.3 11.6 3.4 0.18 12.3 0.6 2.0 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) PDE8 PF08629.10 OWF48772.1 - 0.3 11.1 3.6 4.8 7.3 0.3 3.2 2 0 0 2 2 2 0 PDE8 phosphodiesterase DUF2970 PF11174.8 OWF48772.1 - 2.6 8.0 7.9 5.7 6.9 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DIPSY PF11763.8 OWF48774.1 - 4e-08 33.5 1.6 8.4 6.6 0.0 7.3 1 1 5 8 8 8 2 Cell-wall adhesin ligand-binding C-terminal Kazal_3 PF18434.1 OWF48774.1 - 0.00023 20.9 1.3 9.4 6.1 0.0 6.5 7 1 1 8 8 8 1 Kazal-type serine protease inhibitor domain Lipocalin_2 PF08212.12 OWF48774.1 - 9.9 6.1 39.1 4.1 7.3 2.8 8.7 2 1 9 11 11 11 0 Lipocalin-like domain Pentapeptide_4 PF13599.6 OWF48775.1 - 7.1e-09 35.7 7.8 0.019 15.1 0.1 6.1 2 2 3 6 6 6 5 Pentapeptide repeats (9 copies) HC2 PF07382.11 OWF48775.1 - 0.00017 21.7 0.1 0.38 10.8 0.0 3.5 1 1 1 3 3 3 3 Histone H1-like nucleoprotein HC2 Cupin_2 PF07883.11 OWF48775.1 - 3.7 7.3 10.9 28 4.5 0.1 6.4 4 3 2 7 7 7 0 Cupin domain Pep_M12B_propep PF01562.19 OWF48776.1 - 4e-25 88.7 0.0 6.1e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide zf-HC5HC2H_2 PF13832.6 OWF48777.1 - 1.1e-37 128.6 6.5 1.1e-37 128.6 6.5 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain EPL1 PF10513.9 OWF48777.1 - 1.7e-29 103.2 11.7 1.7e-29 103.2 11.7 5.0 5 1 1 6 6 6 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 OWF48777.1 - 1.5e-25 89.3 3.0 1.5e-25 89.3 3.0 4.4 4 0 0 4 4 4 1 PHD-like zinc-binding domain Bromodomain PF00439.25 OWF48777.1 - 6.1e-23 80.7 1.2 1.5e-22 79.5 1.2 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 OWF48777.1 - 1.1e-14 53.7 3.2 1.1e-14 53.7 3.2 3.3 3 1 1 4 4 4 1 PHD-finger PHD PF00628.29 OWF48777.1 - 2.7e-07 30.4 9.0 2.7e-07 30.4 9.0 3.3 3 0 0 3 3 3 2 PHD-finger zf-SAP30 PF13866.6 OWF48777.1 - 0.017 15.2 0.3 0.051 13.7 0.3 1.9 1 0 0 1 1 1 0 SAP30 zinc-finger zf-C2H2_aberr PF17017.5 OWF48777.1 - 0.028 14.5 0.1 0.067 13.3 0.1 1.7 1 0 0 1 1 1 0 Aberrant zinc-finger PWWP PF00855.17 OWF48778.1 - 1.1e-17 64.2 1.0 1.8e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 PWWP domain AIRS_C PF02769.22 OWF48779.1 - 3.6e-28 98.7 0.0 5.4e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 OWF48779.1 - 5.5e-10 39.8 0.2 1.4e-09 38.5 0.2 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF229 PF02995.17 OWF48780.1 - 1.3e-120 403.3 2.0 1.7e-120 403.0 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF48780.1 - 0.00022 20.7 0.6 0.0032 16.9 0.0 2.2 1 1 1 2 2 2 1 Sulfatase DUF1501 PF07394.12 OWF48780.1 - 0.077 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 OWF48780.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase HECT PF00632.25 OWF48784.1 - 3.8e-12 46.3 0.1 1.4e-11 44.5 0.1 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Zmiz1_N PF18028.1 OWF48784.1 - 0.02 15.2 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain zf-C2HC5 PF06221.13 OWF48784.1 - 0.04 13.9 0.3 0.1 12.6 0.3 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type 7tm_1 PF00001.21 OWF48786.1 - 3.7e-23 82.2 14.0 6.4e-23 81.4 14.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF48786.1 - 2.5e-18 66.5 23.3 3.6e-18 65.9 23.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Sdh_cyt PF01127.22 OWF48786.1 - 0.48 10.5 3.6 11 6.1 0.6 2.6 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit rve PF00665.26 OWF48787.1 - 1e-19 70.9 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OWF48787.1 - 5.6e-08 32.8 0.2 1.5e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OWF48787.1 - 0.00031 20.5 0.0 0.00078 19.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OWF48787.1 - 0.06 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Pentapeptide_4 PF13599.6 OWF48789.1 - 0.011 15.8 0.0 23 5.2 0.0 4.4 3 2 2 5 5 5 0 Pentapeptide repeats (9 copies) NDUF_B7 PF05676.13 OWF48790.1 - 5.1 6.9 38.1 0.43 10.3 0.4 6.5 2 1 4 6 6 6 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF29 PF01724.16 OWF48792.1 - 0.18 12.0 0.2 3.4 7.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF29 PC4 PF02229.16 OWF48793.1 - 2e-11 43.3 0.4 5.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) SNF PF00209.18 OWF48794.1 - 9.6e-179 595.4 37.6 1.2e-178 595.1 37.6 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family C1q PF00386.21 OWF48795.1 - 2.4e-13 50.4 0.0 4.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 C1q domain SlyX PF04102.12 OWF48795.1 - 0.0059 17.2 2.0 0.015 15.9 2.0 1.7 1 0 0 1 1 1 1 SlyX DUF2046 PF09755.9 OWF48795.1 - 0.0065 15.7 2.1 0.0082 15.4 2.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) TelA PF05816.11 OWF48795.1 - 0.017 14.2 0.6 0.023 13.8 0.6 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) TMF_DNA_bd PF12329.8 OWF48795.1 - 0.032 14.2 0.7 0.064 13.3 0.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding E2R135 PF11570.8 OWF48795.1 - 0.087 13.1 0.2 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 PKcGMP_CC PF16808.5 OWF48795.1 - 0.28 11.1 1.5 0.54 10.2 0.6 1.7 1 1 2 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 OWF48795.1 - 0.52 10.5 5.2 0.074 13.3 1.2 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APCDDC PF14921.6 OWF48796.1 - 4e-92 307.9 2.9 8.7e-70 234.8 0.5 2.5 2 1 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 CFC PF09443.10 OWF48796.1 - 5.8 6.9 5.3 14 5.6 0.1 3.0 3 0 0 3 3 3 0 Cripto_Frl-1_Cryptic (CFC) Vault PF01505.18 OWF48798.1 - 0.65 10.2 1.8 49 4.2 0.0 3.2 3 0 0 3 3 3 0 Major Vault Protein repeat domain DEAD PF00270.29 OWF48801.1 - 2.6e-07 30.6 0.0 3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OWF48801.1 - 0.052 13.5 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Myb_DNA-bind_5 PF13873.6 OWF48802.1 - 3.6e-19 68.6 2.2 5.1e-19 68.1 2.2 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF5617 PF18493.1 OWF48803.1 - 0.07 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) 7tm_1 PF00001.21 OWF48804.1 - 4.9e-42 144.1 25.9 7.8e-42 143.4 25.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zinc_ribbon_15 PF17032.5 OWF48804.1 - 0.089 13.5 1.3 0.32 11.8 1.3 2.0 1 1 0 1 1 1 0 zinc-ribbon family 7TM_GPCR_Srsx PF10320.9 OWF48804.1 - 0.16 11.4 26.7 0.27 10.6 26.7 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF48804.1 - 2.4 7.7 32.3 0.17 11.5 19.9 2.9 3 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx UPF0029 PF01205.19 OWF48806.1 - 2.2e-35 121.1 0.1 5.8e-35 119.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OWF48806.1 - 2.8e-19 69.5 0.5 5.7e-19 68.5 0.5 1.5 1 0 0 1 1 1 1 RWD domain DUF4600 PF15372.6 OWF48806.1 - 0.057 13.8 0.3 5.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) BNIP2 PF12496.8 OWF48806.1 - 0.21 12.0 1.9 0.23 11.9 1.0 1.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PS_Dcarbxylase PF02666.15 OWF48807.1 - 6.4e-64 215.2 0.0 8.3e-64 214.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 OWF48807.1 - 0.0003 20.4 0.0 0.0008 19.0 0.0 1.7 1 0 0 1 1 1 1 MNLL subunit Peptidase_M23 PF01551.22 OWF48807.1 - 0.052 13.8 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M23 Pkinase_Tyr PF07714.17 OWF48808.1 - 2.2e-44 151.7 0.0 6.9e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OWF48808.1 - 1.9e-39 135.7 0.0 4.4e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Death PF00531.22 OWF48808.1 - 1.3e-05 25.2 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Death domain ABC1 PF03109.16 OWF48808.1 - 0.1 12.8 0.0 0.49 10.6 0.0 2.2 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 OWF48808.1 - 9.3 4.9 11.3 0.17 10.7 0.1 2.9 4 0 0 4 4 4 0 Fungal protein kinase CS PF04969.16 OWF48809.1 - 1.5e-12 48.3 0.0 4.3e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 CS domain DUF2415 PF10313.9 OWF48809.1 - 0.056 13.4 0.1 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF218 PF02698.17 OWF48810.1 - 2.6e-18 66.3 0.0 3.4e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain DUF218 PF02698.17 OWF48811.1 - 8.8e-20 71.1 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Kinesin PF00225.23 OWF48812.1 - 5.7e-107 357.5 0.1 5.7e-107 357.5 0.1 2.9 5 0 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 OWF48812.1 - 8.1e-28 97.2 0.8 5.6e-27 94.5 0.0 2.9 2 0 0 2 2 2 1 Microtubule binding DUF2205 PF10224.9 OWF48812.1 - 0.025 14.5 0.1 0.025 14.5 0.1 7.9 7 1 1 8 8 8 0 Short coiled-coil protein HMMR_C PF15908.5 OWF48813.1 - 3.4e-06 27.4 13.0 3.4e-06 27.4 13.0 2.8 1 1 2 3 3 3 1 Hyaluronan mediated motility receptor C-terminal UPF0242 PF06785.11 OWF48813.1 - 0.0059 16.7 15.3 0.0059 16.7 15.3 3.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus PAGK PF15284.6 OWF48813.1 - 0.024 14.6 0.1 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 Phage-encoded virulence factor CENP-F_leu_zip PF10473.9 OWF48813.1 - 0.025 14.6 1.6 0.025 14.6 1.6 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1045 PF06299.12 OWF48813.1 - 0.1 12.6 2.2 0.27 11.2 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) ERM PF00769.19 OWF48813.1 - 0.55 10.0 46.6 0.046 13.5 32.6 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Mod_r PF07200.13 OWF48813.1 - 1.3 9.1 36.0 0.018 15.2 13.3 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.12 OWF48813.1 - 7.9 4.9 7.3 5.6 5.4 2.1 1.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family cEGF PF12662.7 OWF48814.1 - 0.047 13.6 6.9 0.83 9.6 0.7 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like hEGF PF12661.7 OWF48814.1 - 0.061 14.0 5.4 3.6 8.4 0.4 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_CA PF07645.15 OWF48814.1 - 0.062 13.5 10.9 1.8 8.8 2.9 3.0 2 0 0 2 2 2 0 Calcium-binding EGF domain EGF_3 PF12947.7 OWF48814.1 - 0.13 12.5 15.8 0.096 12.9 2.6 2.9 2 0 0 2 2 2 0 EGF domain dCache_1 PF02743.18 OWF48814.1 - 0.19 11.5 9.1 4.5 7.0 0.3 3.2 2 2 0 2 2 2 0 Cache domain FXa_inhibition PF14670.6 OWF48814.1 - 4.9 7.5 11.5 2 8.8 1.3 2.6 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site TIR PF01582.20 OWF48815.1 - 8e-23 81.1 0.1 1.1e-22 80.7 0.1 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF48815.1 - 2.8e-12 47.3 0.0 4.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain Glycophorin_A PF01102.18 OWF48815.1 - 0.0049 17.1 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycophorin A tRNA_int_endo PF01974.17 OWF48815.1 - 0.035 14.2 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain SPP PF06550.11 OWF48815.1 - 0.049 13.1 1.5 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease TIR PF01582.20 OWF48816.1 - 2.1e-23 83.0 0.0 2.4e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF48816.1 - 8.8e-13 48.9 0.0 1.1e-12 48.6 0.0 1.1 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 OWF48816.1 - 0.032 14.6 0.1 0.092 13.1 0.1 1.7 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF871 PF05913.11 OWF48816.1 - 0.059 12.6 0.0 0.095 11.9 0.0 1.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF871) TIR PF01582.20 OWF48817.1 - 7.8e-22 77.9 0.1 1.1e-21 77.4 0.1 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF48817.1 - 7.6e-13 49.1 0.0 1.3e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF48817.1 - 0.00022 20.9 0.0 0.014 15.1 0.0 1.9 1 1 1 2 2 2 2 Leucine rich repeat Glycophorin_A PF01102.18 OWF48817.1 - 0.002 18.4 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A LRR_4 PF12799.7 OWF48817.1 - 0.0075 16.7 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) TPKR_C2 PF16920.5 OWF48817.1 - 0.12 12.5 0.3 0.24 11.6 0.3 1.5 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain tRNA_int_endo PF01974.17 OWF48817.1 - 0.15 12.1 0.1 0.38 10.9 0.1 1.7 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain DUF871 PF05913.11 OWF48817.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Glyco_transf_11 PF01531.16 OWF48818.1 - 0.035 13.3 0.1 0.07 12.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 11 EF-hand_6 PF13405.6 OWF48819.1 - 2.6e-06 26.9 0.2 0.026 14.4 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF48819.1 - 2.9e-06 26.4 0.0 0.035 13.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF48819.1 - 2.1e-05 24.9 0.3 0.21 12.1 0.2 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF48819.1 - 0.0092 15.8 0.1 1.1 9.1 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF48819.1 - 0.016 14.7 0.3 0.39 10.3 0.0 2.7 2 0 0 2 2 2 0 EF hand Tmemb_161AB PF10268.9 OWF48820.1 - 4.4e-182 606.0 13.9 4.9e-182 605.8 13.9 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB AtpR PF12966.7 OWF48820.1 - 0.0089 16.4 1.8 0.048 14.1 1.8 2.3 1 0 0 1 1 1 1 N-ATPase, AtpR subunit ATE_C PF04377.15 OWF48821.1 - 5.2e-55 185.7 8.6 2.2e-47 161.1 4.2 2.4 2 0 0 2 2 2 2 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OWF48821.1 - 1.4e-27 95.9 6.0 6.9e-27 93.7 5.3 2.4 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus IL4 PF00727.18 OWF48821.1 - 0.2 11.9 2.2 0.21 11.8 0.2 2.0 2 0 0 2 2 2 0 Interleukin 4 Transket_pyr PF02779.24 OWF48822.1 - 1.2e-42 145.6 0.0 2.1e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OWF48822.1 - 1.4e-33 115.4 0.0 2.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Leptin PF02024.15 OWF48823.1 - 1.4 8.7 6.0 9.3 6.0 0.2 3.2 1 1 3 4 4 4 0 Leptin Drf_FH1 PF06346.12 OWF48823.1 - 2.2 8.0 19.3 29 4.4 14.8 2.5 2 1 0 2 2 2 0 Formin Homology Region 1 Trypan_PARP PF05887.11 OWF48824.1 - 0.3 11.1 0.3 0.43 10.6 0.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Med31 PF05669.12 OWF48824.1 - 1.2 9.1 15.0 0.74 9.9 2.7 3.0 1 1 1 2 2 2 0 SOH1 Tcp10_C PF07202.13 OWF48825.1 - 0.01 15.8 22.1 1.2 9.1 2.3 3.8 1 1 3 4 4 4 0 T-complex protein 10 C-terminus ANF_receptor PF01094.28 OWF48826.1 - 1.7e-72 244.5 0.0 2.3e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 OWF48826.1 - 3.4e-53 180.8 26.0 6e-53 180.0 26.0 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 OWF48826.1 - 2e-13 50.1 14.9 2e-13 50.1 14.9 2.3 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 OWF48826.1 - 2.4e-05 24.2 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Tub PF01167.18 OWF48827.1 - 1.1e-91 306.9 0.0 1.6e-91 306.4 0.0 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 OWF48827.1 - 0.044 13.4 0.2 0.76 9.3 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3527) SPOC PF07744.13 OWF48828.1 - 0.11 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 SPOC domain Pkinase PF00069.25 OWF48829.1 - 5e-68 229.3 0.0 9.7e-68 228.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF48829.1 - 2.7e-42 144.8 0.0 6.6e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF48829.1 - 4.1e-09 36.2 0.0 1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF48829.1 - 1.6e-07 30.9 0.1 1.6e-07 30.9 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF48829.1 - 9.7e-05 22.4 0.0 0.00024 21.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF48829.1 - 0.00011 21.3 0.2 0.00019 20.5 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OWF48829.1 - 0.0011 17.8 0.9 0.0053 15.6 0.6 2.3 1 1 1 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OWF48829.1 - 0.097 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Sulfotransfer_1 PF00685.27 OWF48830.1 - 1.7e-34 119.6 0.0 9.7e-29 100.7 0.0 2.1 1 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF48830.1 - 3.4e-05 24.3 0.0 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 Sulfotransferase family Peptidase_M1 PF01433.20 OWF48831.1 - 2e-68 230.2 0.9 3.2e-68 229.6 0.9 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OWF48831.1 - 4.5e-48 164.4 0.2 1.2e-47 163.0 0.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OWF48831.1 - 8e-40 137.0 0.1 1.4e-39 136.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_C14 PF00656.22 OWF48832.1 - 4.9e-22 79.1 0.1 1.8e-21 77.2 0.1 1.9 1 1 0 1 1 1 1 Caspase domain Poxvirus PF06227.12 OWF48832.1 - 0.0041 16.9 1.4 0.0048 16.7 0.3 1.7 2 0 0 2 2 2 1 dsDNA Poxvirus HSR PF03172.13 OWF48832.1 - 0.062 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 HSR domain Lectin_C PF00059.21 OWF48833.1 - 0.0095 16.7 2.1 0.046 14.5 0.1 2.6 2 1 1 3 3 3 1 Lectin C-type domain Stevor PF17410.2 OWF48833.1 - 0.01 15.4 0.4 0.017 14.7 0.0 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 OWF48833.1 - 0.012 16.5 0.0 0.022 15.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OWF48833.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Syndecan PF01034.20 OWF48833.1 - 0.02 14.8 0.5 0.046 13.6 0.5 1.5 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 OWF48833.1 - 0.021 14.6 0.3 0.037 13.8 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gram_pos_anchor PF00746.21 OWF48833.1 - 0.23 11.4 1.0 0.49 10.4 1.0 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif RIFIN PF02009.16 OWF48833.1 - 1.1 9.0 7.6 0.19 11.6 1.6 2.4 2 1 0 2 2 2 0 Rifin Flp1_like PF16982.5 OWF48833.1 - 9.3 5.7 9.1 18 4.9 9.1 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain SRCR PF00530.18 OWF48834.1 - 1e-34 119.0 7.0 2.2e-19 69.8 0.9 3.9 4 1 0 4 4 4 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF48834.1 - 1.2e-10 41.7 6.6 7.6e-05 23.2 0.1 3.3 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain EB PF01683.18 OWF48834.1 - 0.0011 19.2 5.8 0.0011 19.2 5.8 6.9 2 1 4 6 6 6 3 EB module RBM39linker PF15519.6 OWF48834.1 - 0.017 16.2 0.4 68 4.6 0.0 3.3 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein GatD_N PF18195.1 OWF48834.1 - 0.2 11.0 0.0 14 5.1 0.0 2.5 2 0 0 2 2 2 0 GatD N-terminal domain AAA_lid_8 PF17868.1 OWF48834.1 - 0.65 9.9 2.9 91 3.1 0.1 3.4 3 0 0 3 3 3 0 AAA lid domain RSF PF14876.6 OWF48834.1 - 3.6 6.4 14.2 5.8 5.8 0.8 3.2 3 0 0 3 3 3 0 Respiratory growth transcriptional regulator Lectin_C PF00059.21 OWF48835.1 - 1.5e-14 54.7 1.5 2.1e-14 54.2 1.5 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF48835.1 - 4.4e-05 23.2 0.2 9.7e-05 22.1 0.2 1.6 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF1724 PF08350.10 OWF48836.1 - 0.044 13.9 3.5 5.3 7.2 0.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1724) Invas_SpaK PF03519.14 OWF48837.1 - 0.12 12.4 0.3 0.64 10.1 0.1 1.8 1 1 1 2 2 2 0 Invasion protein B family DUF4713 PF15831.5 OWF48838.1 - 0.0086 16.5 0.5 0.014 15.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) DNA_pol3_a_NII PF11490.8 OWF48839.1 - 0.034 14.0 0.6 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Cyclin_C_2 PF16899.5 OWF48839.1 - 0.096 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin C-terminal domain PDEase_I PF00233.19 OWF48840.1 - 1.3e-77 260.8 2.6 1.3e-77 260.8 2.6 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase AIF-MLS PF14962.6 OWF48840.1 - 0.014 15.4 4.6 0.024 14.6 4.6 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence SgrT PF15894.5 OWF48841.1 - 0.0037 17.2 7.3 1.4 8.9 0.1 4.0 1 1 3 4 4 4 2 Inhibitor of glucose uptake transporter SgrT Nanovirus_coat PF04660.12 OWF48841.1 - 0.0044 17.1 1.1 2.3 8.3 0.2 2.5 1 1 1 2 2 2 2 Nanovirus coat protein DUF2594 PF10769.9 OWF48841.1 - 0.18 11.9 1.7 26 4.9 0.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2594) DUF5534 PF17686.1 OWF48841.1 - 0.2 11.9 0.8 7.1 6.8 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5534) ELM2 PF01448.24 OWF48842.1 - 1.7e-09 38.3 2.6 2e-09 38.1 0.1 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 OWF48842.1 - 0.001 19.2 0.1 0.0021 18.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OWF48842.1 - 0.002 17.9 0.2 0.0069 16.3 0.2 1.9 1 0 0 1 1 1 1 Myb DNA-binding like WD40 PF00400.32 OWF48843.1 - 8.5e-09 35.9 3.3 0.0051 17.6 0.1 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF48843.1 - 2e-05 24.8 0.1 2.8 8.3 0.0 4.6 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 OWF48843.1 - 0.0039 16.2 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 OWF48843.1 - 0.018 13.4 0.0 0.028 12.7 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1069 PF06370.11 OWF48844.1 - 0.00059 19.5 2.6 1.8 8.1 0.1 3.5 1 1 3 4 4 4 2 Protein of unknown function (DUF1069) GN3L_Grn1 PF08701.11 OWF48844.1 - 0.001 19.2 0.1 8 6.6 0.0 4.6 2 2 3 5 5 5 1 GNL3L/Grn1 putative GTPase Shal-type PF11601.8 OWF48844.1 - 0.0072 15.8 0.0 84 2.8 0.0 5.3 7 0 0 7 7 7 0 Shal-type voltage-gated potassium channels, N-terminal DUF3369 PF11849.8 OWF48844.1 - 0.01 16.0 0.2 7.3 6.8 0.1 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF3369) Ald_deCOase PF11266.8 OWF48844.1 - 0.072 12.8 1.7 12 5.6 0.1 2.9 1 1 3 4 4 4 0 Long-chain fatty aldehyde decarbonylase Zein PF01559.16 OWF48844.1 - 0.077 12.6 0.4 0.31 10.6 0.4 1.6 1 1 0 1 1 1 0 Zein seed storage protein YjcZ PF13990.6 OWF48844.1 - 0.13 11.7 0.4 3.2 7.1 0.1 1.8 1 1 0 1 1 1 0 YjcZ-like protein Aida_N PF08910.10 OWF48844.1 - 0.18 12.2 0.0 5.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Aida N-terminus Bacillus_PapR PF05968.11 OWF48844.1 - 0.19 11.7 4.4 44 4.0 0.0 5.5 7 0 0 7 7 7 0 Bacillus PapR protein NACHT PF05729.12 OWF48845.1 - 2e-06 27.8 0.0 4.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OWF48845.1 - 0.00011 22.5 0.0 0.00035 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OWF48845.1 - 0.00018 21.9 0.0 0.00039 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 OWF48845.1 - 0.00086 19.6 0.0 3.7 7.9 0.0 4.8 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 OWF48845.1 - 0.038 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OWF48845.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PQQ_2 PF13360.6 OWF48845.1 - 0.13 11.8 0.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain Phosphodiest PF01663.22 OWF48846.1 - 9.4e-80 268.9 4.1 1.1e-79 268.6 4.1 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF48846.1 - 2.6e-12 46.8 0.1 7.2e-06 25.6 0.0 2.5 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 OWF48846.1 - 5.4e-10 39.1 0.0 1.6e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 OWF48847.1 - 1.8e-80 271.2 5.8 2.2e-80 271.0 5.8 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF48847.1 - 4.4e-12 46.0 2.0 2.8e-09 36.8 1.9 2.8 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 OWF48847.1 - 3e-06 26.8 0.1 6.5e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 OWF48847.1 - 0.05 12.2 0.1 0.06 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DAGK_cat PF00781.24 OWF48848.1 - 7.1e-21 74.1 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GREB1 PF15782.5 OWF48849.1 - 0.12 9.5 11.0 0.48 7.5 3.6 2.1 1 1 1 2 2 2 0 Gene regulated by oestrogen in breast cancer DUF2829 PF11195.8 OWF48849.1 - 0.26 11.5 10.5 6.9e+02 0.6 10.5 3.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2829) DUF2130 PF09903.9 OWF48849.1 - 0.36 10.1 3.1 0.41 9.9 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF4358 PF14270.6 OWF48849.1 - 3.6 7.9 16.0 1.3 9.4 1.9 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4358) GhoS PF11080.8 OWF48849.1 - 6.9 6.7 20.3 13 5.9 0.5 5.0 2 2 0 3 3 3 0 Endoribonuclease GhoS DAGK_cat PF00781.24 OWF48850.1 - 1.5e-26 92.5 0.0 2.4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CAP PF00188.26 OWF48851.1 - 5.5e-21 75.7 1.8 1.2e-20 74.6 1.4 1.8 1 1 1 2 2 2 1 Cysteine-rich secretory protein family ShK PF01549.24 OWF48851.1 - 6.5e-13 49.0 22.5 3.3e-06 27.5 8.6 3.2 2 0 0 2 2 2 2 ShK domain-like Utp21 PF04192.12 OWF48852.1 - 2.4e-62 210.5 0.1 3.9e-62 209.8 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 OWF48852.1 - 2.6e-17 62.9 28.3 4.8e-07 30.4 0.4 10.7 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF48852.1 - 2.3e-14 53.4 0.6 0.00015 22.0 0.0 6.6 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain SIR2 PF02146.17 OWF48853.1 - 5.5e-27 94.8 0.1 1.2e-25 90.4 0.1 2.5 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OWF48853.1 - 0.13 12.0 0.0 7 6.4 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Tctex-1 PF03645.13 OWF48854.1 - 2.5e-24 85.5 0.6 4.1e-24 84.8 0.6 1.3 1 0 0 1 1 1 1 Tctex-1 family Tctex-1 PF03645.13 OWF48855.1 - 2.3e-22 79.2 1.0 3.6e-22 78.5 1.0 1.3 1 0 0 1 1 1 1 Tctex-1 family zf-H2C2_2 PF13465.6 OWF48856.1 - 5.3e-11 42.4 9.1 1.9e-07 31.2 2.3 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF48856.1 - 1.7e-09 37.6 26.2 9.4e-05 22.7 5.2 4.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF48856.1 - 0.0007 20.2 9.9 0.003 18.2 3.5 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger MMR1 PF08505.10 OWF48856.1 - 0.0024 18.2 2.3 0.0024 18.2 2.3 2.0 2 0 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein zf-C2H2_8 PF15909.5 OWF48856.1 - 0.13 12.6 6.3 0.41 11.0 6.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 OWF48856.1 - 0.17 12.4 4.4 7.9 7.0 0.5 3.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 OWF48856.1 - 0.19 12.1 6.0 6.4 7.2 0.9 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF48856.1 - 0.37 11.2 7.9 3.9 8.0 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Thioredoxin PF00085.20 OWF48857.1 - 7.3e-08 32.3 0.1 4.3e-05 23.5 0.0 4.1 5 0 0 5 5 5 1 Thioredoxin Thioredoxin_6 PF13848.6 OWF48857.1 - 9.9e-05 22.3 0.8 0.11 12.5 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OWF48857.1 - 0.081 13.3 5.9 3.1 8.2 0.1 4.5 5 1 0 5 5 5 0 Thioredoxin-like Thioredoxin_2 PF13098.6 OWF48857.1 - 0.085 13.3 1.0 6 7.4 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin-like domain Actin PF00022.19 OWF48858.1 - 1.1e-150 501.8 0.0 3.6e-150 500.1 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 OWF48859.1 - 1.6e-152 507.9 0.0 5.1e-152 506.2 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 OWF48860.1 - 2.1e-151 504.2 0.0 6.8e-151 502.5 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 OWF48861.1 - 5e-261 865.2 0.0 3.8e-144 480.3 0.0 3.1 2 2 0 2 2 2 2 Actin GerD PF17898.1 OWF48861.1 - 0.024 14.6 0.3 0.9 9.5 0.1 2.4 2 0 0 2 2 2 0 Spore germination GerD central core domain MreB_Mbl PF06723.13 OWF48861.1 - 0.054 12.3 0.0 2.7 6.7 0.0 2.8 3 0 0 3 3 3 0 MreB/Mbl protein Ribosomal_L7Ae PF01248.26 OWF48862.1 - 5.2e-08 32.5 0.2 8.7e-08 31.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L7Ae PF01248.26 OWF48863.1 - 3.3e-07 29.9 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L7Ae PF01248.26 OWF48864.1 - 4.4e-06 26.3 0.1 6.5e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Paramyxo_P_V_N PF13825.6 OWF48864.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus AAL_decarboxy PF03306.13 OWF48864.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase Ribosomal_L7Ae PF01248.26 OWF48865.1 - 0.00096 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MnmE_helical PF12631.7 OWF48865.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain Ribosomal_L7Ae PF01248.26 OWF48866.1 - 4.6e-09 35.9 0.0 8.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 OWF48866.1 - 0.12 12.2 1.4 7 6.6 0.1 2.7 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_CoA_synt_C PF08540.10 OWF48867.1 - 8.7e-104 347.1 0.1 1.1e-103 346.7 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 OWF48867.1 - 2.4e-93 310.8 0.6 3.5e-93 310.3 0.6 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 OWF48867.1 - 0.0056 16.5 0.8 0.012 15.4 0.8 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Vitellogenin_N PF01347.22 OWF48868.1 - 4.9e-89 299.4 0.0 1.2e-88 298.1 0.0 1.7 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.11 OWF48868.1 - 2.8e-74 250.2 3.6 6.6e-74 248.9 3.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) VWD PF00094.25 OWF48868.1 - 2.3e-24 86.5 2.3 4.6e-23 82.2 0.0 4.2 3 0 0 3 3 3 1 von Willebrand factor type D domain DUF1081 PF06448.11 OWF48868.1 - 5.1e-08 33.3 0.0 5.1e-08 33.3 0.0 6.0 7 1 1 8 8 8 1 Domain of Unknown Function (DUF1081) Apolipoprotein PF01442.18 OWF48868.1 - 4e-05 23.6 9.1 4e-05 23.6 9.1 2.5 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain C8 PF08742.11 OWF48868.1 - 0.00017 21.9 4.3 0.00035 20.9 4.3 1.6 1 0 0 1 1 1 1 C8 domain Prominin PF05478.11 OWF48868.1 - 0.049 11.6 11.5 0.027 12.4 8.3 1.9 1 1 1 2 2 2 0 Prominin CREPT PF16566.5 OWF48868.1 - 0.32 11.2 8.3 1.4 9.1 1.5 2.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 OWF48868.1 - 3.1 7.9 8.2 0.76 9.8 0.3 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) MT-A70 PF05063.14 OWF48869.1 - 6.7e-37 127.0 1.2 1.2e-36 126.2 1.2 1.4 1 0 0 1 1 1 1 MT-A70 APG6_N PF17675.1 OWF48870.1 - 0.0024 18.4 86.8 0.085 13.4 13.8 5.4 1 1 4 5 5 5 4 Apg6 coiled-coil region DUF2730 PF10805.8 OWF48870.1 - 2.8 8.1 37.3 0.19 11.9 0.5 5.7 2 2 0 5 5 5 0 Protein of unknown function (DUF2730) OmpH PF03938.14 OWF48870.1 - 8.8 6.7 83.1 0.045 14.1 3.1 6.1 2 2 4 6 6 6 0 Outer membrane protein (OmpH-like) WD40 PF00400.32 OWF48871.1 - 3.9e-18 65.5 5.0 1.6e-07 31.9 0.8 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat SH3_1 PF00018.28 OWF48871.1 - 1.7e-16 59.5 0.1 8e-16 57.4 0.1 2.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF48871.1 - 1.4e-14 53.7 0.1 6.5e-14 51.5 0.1 2.3 1 0 0 1 1 1 1 Variant SH3 domain ANAPC4_WD40 PF12894.7 OWF48871.1 - 1.4e-09 38.1 0.1 0.35 11.2 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SH3_2 PF07653.17 OWF48871.1 - 2.3e-09 36.8 0.0 7.6e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Nup160 PF11715.8 OWF48871.1 - 0.029 13.0 0.1 0.34 9.5 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF4648 PF15505.6 OWF48871.1 - 0.035 15.0 0.1 0.18 12.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) DUF4115 PF13464.6 OWF48872.1 - 7.9 6.7 27.5 53 4.1 0.1 9.9 2 1 9 12 12 12 0 Domain of unknown function (DUF4115) Trypsin PF00089.26 OWF48873.1 - 3.3e-63 213.5 4.5 4.6e-63 213.0 4.5 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF48873.1 - 2.9e-07 31.5 1.6 3.9e-07 31.1 0.9 1.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF48873.1 - 0.092 13.1 0.2 0.21 12.0 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) DNA_pol_A_exo1 PF01612.20 OWF48874.1 - 1.1e-10 41.5 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease MIB_HERC2 PF06701.13 OWF48875.1 - 2.3e-44 149.5 17.2 2.5e-26 91.7 4.0 3.5 3 0 0 3 3 3 2 Mib_herc2 SH3_15 PF18346.1 OWF48875.1 - 1.1e-43 147.3 4.5 5.4e-21 74.7 0.0 3.3 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain Ank_2 PF12796.7 OWF48875.1 - 1.8e-43 147.0 8.5 2.3e-12 47.3 0.0 5.3 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF48875.1 - 8.9e-42 140.6 11.1 5.5e-09 36.1 0.0 7.6 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF48875.1 - 4.2e-34 116.5 11.3 1.2e-08 35.3 0.5 6.7 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF48875.1 - 1.8e-30 104.0 13.9 4.4e-05 23.7 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 OWF48875.1 - 6.2e-28 93.8 6.9 0.0024 18.2 0.0 10.5 11 0 0 11 11 10 6 Ankyrin repeat zf-C3HC4_3 PF13920.6 OWF48875.1 - 2e-27 94.8 56.8 3e-11 43.0 11.5 4.5 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 OWF48875.1 - 1.1e-09 37.9 8.4 1.1e-09 37.9 8.4 4.3 4 0 0 4 4 4 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 OWF48875.1 - 8.2e-09 35.2 10.3 8.2e-09 35.2 10.3 4.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF48875.1 - 0.003 17.4 56.5 0.049 13.5 10.8 5.4 4 1 1 5 5 5 3 Prokaryotic RING finger family 4 DUF4314 PF14192.6 OWF48875.1 - 0.59 10.1 3.3 15 5.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) SNURF PF07192.11 OWF48876.1 - 2 8.3 5.4 0.61 10.0 0.2 2.8 4 0 0 4 4 4 0 SNURF/RPN4 protein Rieske PF00355.26 OWF48877.1 - 9.4e-12 44.7 0.2 2.7e-11 43.2 0.1 1.7 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OWF48877.1 - 2.2e-11 43.6 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Glyco_transf_11 PF01531.16 OWF48878.1 - 1.2e-37 129.8 0.8 1.4e-37 129.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 NodZ PF05830.11 OWF48878.1 - 0.03 13.2 0.0 0.72 8.6 0.1 2.1 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) O-FucT PF10250.9 OWF48878.1 - 0.12 12.0 0.3 1.5 8.4 0.2 2.1 1 1 1 2 2 2 0 GDP-fucose protein O-fucosyltransferase Yip1 PF04893.17 OWF48880.1 - 3.7e-17 62.6 17.3 5.2e-17 62.1 17.3 1.3 1 0 0 1 1 1 1 Yip1 domain Asp-Al_Ex PF06826.12 OWF48880.1 - 0.076 12.8 6.3 0.79 9.5 3.5 2.2 1 1 1 2 2 2 0 Predicted Permease Membrane Region DUF2070 PF09843.9 OWF48880.1 - 0.081 11.2 5.9 0.11 10.8 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fic PF02661.18 OWF48880.1 - 0.13 13.2 0.2 0.8 10.6 0.0 2.3 2 1 1 3 3 3 0 Fic/DOC family Aim21 PF11489.8 OWF48880.1 - 1.3 7.9 10.7 0.13 11.1 5.9 1.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 21 UCR_hinge PF02320.16 OWF48881.1 - 2.1e-23 82.3 9.7 3e-23 81.8 9.7 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DERM PF14704.6 OWF48882.1 - 0.036 14.5 0.5 0.036 14.5 0.5 3.8 4 1 0 4 4 4 0 Dermatopontin DUF3638 PF12340.8 OWF48883.1 - 0.26 10.6 3.6 3 7.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3638) DUF4458 PF14660.6 OWF48883.1 - 0.55 10.5 6.3 0.66 10.2 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4458) Phytochelatin_C PF09328.10 OWF48884.1 - 0.019 14.3 1.9 35 3.6 0.0 4.7 3 2 2 5 5 5 0 Domain of unknown function (DUF1984) MgtE_N PF03448.17 OWF48884.1 - 0.023 15.3 0.0 11 6.7 0.0 2.1 2 0 0 2 2 2 0 MgtE intracellular N domain DEK_C PF08766.11 OWF48884.1 - 0.16 11.9 9.0 13 5.8 0.0 6.3 3 3 6 10 10 10 0 DEK C terminal domain PBECR3 PF18812.1 OWF48884.1 - 0.26 11.2 3.4 49 3.9 0.2 4.1 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 URO-D PF01208.17 OWF48885.1 - 3.5e-115 384.8 0.0 4.3e-115 384.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PKcGMP_CC PF16808.5 OWF48886.1 - 0.0066 16.3 10.9 0.63 9.9 2.0 3.4 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Exonuc_VII_L PF02601.15 OWF48886.1 - 0.1 12.1 8.7 0.12 11.9 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RcbX PF02341.15 OWF48886.1 - 0.16 12.2 4.5 0.17 12.2 1.8 2.1 1 1 1 2 2 2 0 RbcX protein Matrilin_ccoil PF10393.9 OWF48886.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Svf1_C PF17187.4 OWF48886.1 - 0.42 10.4 2.3 0.8 9.5 2.3 1.5 1 1 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain TMPIT PF07851.13 OWF48886.1 - 0.44 9.8 6.1 0.59 9.3 6.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein ING PF12998.7 OWF48886.1 - 0.49 11.0 9.6 0.98 10.0 9.6 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding FAM76 PF16046.5 OWF48886.1 - 0.74 9.1 9.5 1.2 8.4 9.5 1.4 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 OWF48886.1 - 0.76 8.6 15.3 1.1 8.1 15.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 OWF48886.1 - 1 8.6 3.5 1.5 8.1 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 OWF48886.1 - 1.2 9.5 15.3 2.1 8.8 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) UPF0242 PF06785.11 OWF48886.1 - 1.6 8.8 19.1 2.4 8.2 19.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Spc19 PF08287.11 OWF48886.1 - 1.8 8.4 14.6 3.4 7.6 14.4 1.6 1 1 0 1 1 1 0 Spc19 SPT16 PF08644.11 OWF48886.1 - 2.6 8.2 8.5 5.1 7.3 8.5 1.5 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF3552 PF12072.8 OWF48886.1 - 8.1 5.8 18.4 1.4 8.3 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) FapA PF03961.13 OWF48886.1 - 8.4 4.9 9.5 11 4.5 9.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 OWF48886.1 - 9.3 5.0 8.6 25 3.5 7.7 1.8 1 1 1 2 2 2 0 Aluminium activated malate transporter ASF1_hist_chap PF04729.13 OWF48887.1 - 2.6e-71 238.6 0.0 3.2e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone WD40 PF00400.32 OWF48888.1 - 0.00077 20.2 3.1 0.2 12.6 0.0 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat Aa_trans PF01490.18 OWF48889.1 - 8.4e-34 117.0 38.5 1.9e-18 66.4 6.4 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein SAD_SRA PF02182.17 OWF48890.1 - 2.3e-57 193.1 0.2 5.2e-57 191.9 0.2 1.6 1 0 0 1 1 1 1 SAD/SRA domain TTD PF12148.8 OWF48890.1 - 1.4e-50 171.2 2.6 1.6e-50 171.0 0.5 2.2 2 1 0 2 2 2 1 Tandem tudor domain within UHRF1 ubiquitin PF00240.23 OWF48890.1 - 4.2e-13 48.8 0.1 1.1e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family PHD PF00628.29 OWF48890.1 - 4.3e-11 42.5 11.8 4.3e-11 42.5 11.8 3.0 3 1 0 3 3 1 1 PHD-finger zf-C3HC4_3 PF13920.6 OWF48890.1 - 0.00067 19.5 11.9 0.00067 19.5 11.9 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF48890.1 - 0.00084 19.2 15.5 0.00084 19.2 15.5 3.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF48890.1 - 0.0012 18.6 14.1 0.0012 18.6 14.1 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF48890.1 - 0.0023 17.7 10.9 0.0023 17.7 10.9 3.2 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 Agenet PF05641.12 OWF48890.1 - 0.0058 17.1 0.1 1.2 9.7 0.0 3.2 3 0 0 3 3 3 1 Agenet domain Rad60-SLD PF11976.8 OWF48890.1 - 0.0063 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_5 PF14634.6 OWF48890.1 - 0.01 15.7 13.6 0.01 15.7 13.6 3.5 2 1 0 2 2 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 OWF48890.1 - 0.02 15.2 13.5 0.02 15.2 13.5 3.9 3 1 1 4 4 3 0 Ring finger domain BRF1 PF07741.13 OWF48890.1 - 8.9 6.7 12.2 0.22 11.9 3.8 2.7 3 0 0 3 3 3 0 Brf1-like TBP-binding domain FAD_binding_4 PF01565.23 OWF48891.1 - 7.2e-15 54.9 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain CytochromB561_N PF09786.9 OWF48891.1 - 0.073 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-IS66 PF13005.7 OWF48891.1 - 0.075 13.4 0.6 1 9.8 0.0 2.5 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 MFS_1 PF07690.16 OWF48893.1 - 5.4e-30 104.5 33.8 5.4e-30 104.5 33.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OWF48893.1 - 2 6.6 13.2 0.1 10.9 1.1 3.0 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_LBD PF02931.23 OWF48894.1 - 1.4e-31 109.7 0.2 2.4e-31 108.9 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF48894.1 - 2.8e-22 80.0 0.4 1.6e-21 77.4 0.4 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MASE3 PF17159.4 OWF48894.1 - 0.012 15.2 1.9 0.025 14.2 1.9 1.5 1 0 0 1 1 1 0 Membrane-associated sensor domain VirB3 PF05101.13 OWF48894.1 - 8.9 6.6 8.4 0.73 10.1 0.1 3.2 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Neur_chan_memb PF02932.16 OWF48895.1 - 5.4e-13 49.6 7.0 6.6e-13 49.3 7.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Caa3_CtaG PF09678.10 OWF48895.1 - 0.19 11.2 4.5 0.22 11.0 4.5 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF5392 PF17370.2 OWF48895.1 - 4.2 7.4 5.9 11 6.1 0.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5392) ATP-synt_8 PF00895.20 OWF48895.1 - 6.2 7.4 6.0 20 5.7 1.1 2.8 3 0 0 3 3 3 0 ATP synthase protein 8 XPC-binding PF09280.11 OWF48896.1 - 5.4e-06 26.1 0.2 0.74 9.6 0.0 4.5 2 1 3 5 5 5 3 XPC-binding domain PAS_8 PF13188.7 OWF48896.1 - 0.00043 20.2 3.6 4.6 7.4 2.8 5.0 1 1 1 2 2 2 1 PAS domain PI-PLC-Y PF00387.19 OWF48896.1 - 0.2 12.0 0.3 6 7.2 0.0 2.7 1 1 1 2 2 2 0 Phosphatidylinositol-specific phospholipase C, Y domain RbcS PF12338.8 OWF48896.1 - 7.2 6.9 26.4 16 5.8 1.0 5.6 2 1 3 5 5 5 0 Ribulose-1,5-bisphosphate carboxylase small subunit Pentapeptide PF00805.22 OWF48896.1 - 8 6.2 6.8 12 5.7 0.4 3.6 2 1 2 4 4 4 0 Pentapeptide repeats (8 copies) Phage_tail_X PF05489.12 OWF48896.1 - 8.7 6.1 14.1 73 3.1 0.1 4.6 1 1 2 3 3 3 0 Phage Tail Protein X CENP-W PF15510.6 OWF48897.1 - 6.8e-06 26.2 0.9 9.6e-06 25.7 0.4 1.4 2 0 0 2 2 2 1 CENP-W protein Radical_SAM_N PF08497.10 OWF48897.1 - 0.031 13.5 0.2 0.035 13.3 0.2 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal NGP1NT PF08153.12 OWF48898.1 - 4.8e-52 175.5 3.7 1.3e-51 174.2 3.7 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OWF48898.1 - 7.6e-16 58.2 0.3 3.9e-13 49.5 0.0 3.5 3 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF48898.1 - 4.9e-06 26.1 0.1 3.9e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF48898.1 - 0.00013 21.9 0.0 0.00066 19.6 0.0 2.3 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 OWF48898.1 - 0.0041 16.6 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family F5_F8_type_C PF00754.25 OWF48899.1 - 0.082 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 F5/8 type C domain Antimicrobial13 PF08108.11 OWF48899.1 - 0.24 11.5 7.8 2.7 8.2 0.5 3.7 3 0 0 3 3 3 0 Halocidin family Y_phosphatase PF00102.27 OWF48900.1 - 2.1e-77 259.9 0.0 1.3e-40 139.4 0.0 2.0 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF48900.1 - 5e-05 23.1 0.0 0.018 14.8 0.0 3.1 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF48900.1 - 0.00011 22.4 0.0 0.00063 19.9 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF48900.1 - 0.0008 19.4 0.0 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 OWF48900.1 - 0.0062 15.5 0.0 2.8 6.8 0.0 2.3 2 1 0 2 2 2 2 Myotubularin-like phosphatase domain Filament PF00038.21 OWF48901.1 - 9.1e-21 74.7 44.2 3.6e-20 72.8 44.2 2.0 1 1 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 OWF48901.1 - 1.1e-05 25.5 30.9 0.00013 22.0 4.5 4.4 3 2 1 4 4 4 3 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 OWF48901.1 - 0.0065 16.5 31.3 0.0088 16.1 0.0 7.2 6 2 1 7 7 7 2 bZIP transcription factor DUF3450 PF11932.8 OWF48901.1 - 0.0073 15.6 25.5 0.036 13.4 3.0 4.2 2 2 2 4 4 4 2 Protein of unknown function (DUF3450) ATG16 PF08614.11 OWF48901.1 - 0.018 15.3 33.0 0.053 13.8 14.6 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 OWF48901.1 - 0.085 12.3 38.9 0.0078 15.7 21.3 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3072 PF11272.8 OWF48901.1 - 0.14 12.1 0.6 0.56 10.1 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) ADIP PF11559.8 OWF48901.1 - 0.35 10.9 33.9 0.055 13.6 1.6 4.9 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding DUF4472 PF14739.6 OWF48901.1 - 0.47 11.2 25.5 0.052 14.3 2.9 4.2 2 2 3 5 5 5 0 Domain of unknown function (DUF4472) DUF2333 PF10095.9 OWF48901.1 - 0.87 8.5 4.1 0.69 8.9 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Atg14 PF10186.9 OWF48901.1 - 1 8.4 35.4 0.074 12.1 9.0 3.9 1 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 OWF48901.1 - 2.3 6.0 15.0 0.035 12.1 0.3 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 OWF48901.1 - 3.4 7.7 13.3 1.8 8.6 1.2 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 OWF48901.1 - 4.4 8.0 22.6 3.7 8.3 0.4 5.2 3 2 2 5 5 5 0 SlyX APG6_N PF17675.1 OWF48901.1 - 6 7.4 39.5 0.44 11.1 6.5 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region AAA_13 PF13166.6 OWF48901.1 - 7.8 5.0 32.9 1.5 7.3 8.7 3.0 1 1 2 3 3 3 0 AAA domain CBM39 PF15886.5 OWF48902.1 - 3.8e-08 33.2 16.5 4 7.4 0.1 8.0 1 1 7 9 9 9 7 Carbohydrate binding domain (family 32) CH PF00307.31 OWF48902.1 - 0.0013 18.9 0.1 24 5.2 0.0 3.9 1 1 3 4 4 4 1 Calponin homology (CH) domain DUF2011 PF09428.10 OWF48902.1 - 0.002 18.3 6.5 31 4.9 0.3 6.2 1 1 2 3 3 3 0 Fungal protein of unknown function (DUF2011) RNA_pol_Rpb1_1 PF04997.12 OWF48902.1 - 0.13 11.6 0.1 8.5 5.6 0.0 2.5 1 1 0 2 2 2 0 RNA polymerase Rpb1, domain 1 RdRP_4 PF02123.16 OWF48902.1 - 0.15 10.9 4.5 1.6 7.5 0.3 2.6 1 1 2 3 3 3 0 Viral RNA-directed RNA-polymerase FERM_f0 PF16511.5 OWF48902.1 - 0.25 11.7 21.1 60 4.1 0.2 8.7 3 3 6 11 11 11 0 N-terminal or F0 domain of Talin-head FERM DUF1829 PF08862.10 OWF48902.1 - 1.3 9.5 4.8 22 5.6 0.2 3.4 1 1 1 3 3 3 0 Domain of unknown function DUF1829 CBM39 PF15886.5 OWF48903.1 - 0.0011 18.8 3.6 1.4 8.8 0.1 3.0 1 1 2 3 3 3 3 Carbohydrate binding domain (family 32) DUF433 PF04255.14 OWF48903.1 - 0.035 14.0 2.3 0.04 13.8 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF433) MiAMP1 PF09117.10 OWF48904.1 - 0.00065 19.9 43.0 9.4 6.5 1.4 8.0 1 1 4 5 5 5 4 MiAMP1 Herpes_glycop_D PF01537.17 OWF48904.1 - 0.77 9.9 51.4 17 5.6 0.5 8.2 1 1 11 12 12 12 0 Herpesvirus glycoprotein D/GG/GX domain Tudor_1_RapA PF18339.1 OWF48905.1 - 5.8e-05 22.9 0.6 18 5.4 0.0 5.6 3 1 1 6 6 6 3 RapA N-terminal Tudor like domain 1 RNA_pol_Rpb1_5 PF04998.17 OWF48905.1 - 0.37 10.2 2.1 46 3.3 0.0 3.0 1 1 2 3 3 3 0 RNA polymerase Rpb1, domain 5 Vanabin-2 PF11437.8 OWF48906.1 - 3.4 7.9 80.7 17 5.7 2.5 8.5 1 1 9 11 11 11 0 Vanadium-binding protein 2 Tau95 PF09734.9 OWF48907.1 - 7.6e-33 114.3 2.6 1e-32 113.9 0.5 2.1 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 OWF48907.1 - 1.1e-27 96.7 0.0 6.3e-27 94.3 0.0 2.3 1 1 0 1 1 1 1 Tau95 Triple barrel domain RPAP2_Rtr1 PF04181.13 OWF48908.1 - 2e-23 82.5 0.6 6.8e-23 80.8 0.6 2.0 1 0 0 1 1 1 1 Rtr1/RPAP2 family SapB_1 PF05184.15 OWF48908.1 - 0.036 14.1 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Saposin-like type B, region 1 Mab-21 PF03281.14 OWF48909.1 - 0.0015 17.9 0.1 0.0038 16.6 0.1 1.8 1 1 0 1 1 1 1 Mab-21 protein MAPEG PF01124.18 OWF48910.1 - 6.3e-21 74.6 0.0 7.1e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 MAPEG family FadR_C PF07840.12 OWF48910.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 FadR C-terminal domain Zona_pellucida PF00100.23 OWF48911.1 - 3.8e-07 30.2 0.3 4.8e-07 29.8 0.3 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Gp5_C PF06715.12 OWF48911.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.4 2 1 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) VWA PF00092.28 OWF48912.1 - 1.4e-06 28.6 3.0 2.3e-06 28.0 3.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain CDP-OH_P_transf PF01066.21 OWF48913.1 - 0.00023 21.9 1.0 0.0009 20.0 0.1 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF588 PF04535.12 OWF48913.1 - 0.0072 16.1 1.1 0.011 15.5 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) PIG-P PF08510.12 OWF48913.1 - 0.064 13.2 0.5 0.22 11.4 0.5 1.9 1 0 0 1 1 1 0 PIG-P FPL PF09758.9 OWF48913.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein CDP-OH_P_transf PF01066.21 OWF48914.1 - 0.00057 20.6 0.1 0.00057 20.6 0.1 3.4 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase THAP PF05485.12 OWF48916.1 - 2.2e-15 57.3 1.0 2.7e-15 57.1 1.0 1.1 1 0 0 1 1 1 1 THAP domain Lectin_C PF00059.21 OWF48917.1 - 3.7e-12 46.9 0.0 5.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 OWF48917.1 - 0.019 15.0 0.3 0.054 13.5 0.0 1.9 2 0 0 2 2 2 0 PAN domain PAN_4 PF14295.6 OWF48917.1 - 0.06 13.3 0.2 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 PAN domain EGF PF00008.27 OWF48918.1 - 6.2e-30 103.1 138.7 1.1e-06 28.8 8.8 11.3 9 1 1 10 10 10 8 EGF-like domain DSL PF01414.19 OWF48918.1 - 6e-23 80.9 2.6 6e-23 80.9 2.6 7.1 4 2 2 7 7 7 1 Delta serrate ligand MNNL PF07657.13 OWF48918.1 - 1.1e-20 73.4 0.1 1.1e-20 73.4 0.1 5.1 4 3 0 4 4 4 1 N terminus of Notch ligand EGF_2 PF07974.13 OWF48918.1 - 2.3e-14 53.4 162.0 0.0038 17.6 8.1 11.7 11 0 0 11 11 11 9 EGF-like domain hEGF PF12661.7 OWF48918.1 - 3.3e-12 46.6 126.7 0.0016 19.0 2.3 13.1 13 0 0 13 13 13 7 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 OWF48918.1 - 0.0019 18.5 1.5 0.0019 18.5 1.5 9.7 10 2 0 10 10 10 3 Pvs28 EGF domain Laminin_EGF PF00053.24 OWF48918.1 - 5.1 7.3 138.2 1.8 8.7 10.9 11.7 2 2 9 11 11 11 0 Laminin EGF domain Stanniocalcin PF03298.13 OWF48919.1 - 1.5e-09 37.5 4.5 2.4e-09 36.8 4.5 1.2 1 0 0 1 1 1 1 Stanniocalcin family CLZ PF16526.5 OWF48920.1 - 1.4e-25 89.4 9.2 4.5e-25 87.8 9.2 1.9 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ion_trans PF00520.31 OWF48920.1 - 1.5e-25 89.9 16.0 2.1e-25 89.4 16.0 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OWF48920.1 - 7.3e-19 67.6 0.0 1.4e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OWF48920.1 - 0.0013 18.7 4.8 0.0041 17.1 4.7 2.0 1 1 0 1 1 1 1 Ion channel DUF4455 PF14643.6 OWF48920.1 - 0.0043 15.8 0.3 0.0066 15.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DUF148 PF02520.17 OWF48920.1 - 0.0084 16.2 5.3 0.018 15.1 2.6 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF148 DLP_helical PF18709.1 OWF48920.1 - 0.054 12.7 2.5 0.091 12.0 2.5 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain Baculo_PEP_C PF04513.12 OWF48920.1 - 0.12 12.4 2.7 0.82 9.7 2.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.19 OWF48920.1 - 0.32 10.6 2.6 0.63 9.7 2.6 1.4 1 0 0 1 1 1 0 GrpE DUF1043 PF06295.12 OWF48920.1 - 0.45 10.5 3.5 0.79 9.7 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4570 PF15134.6 OWF48920.1 - 0.54 10.3 4.7 1.3 9.1 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF1843 PF08898.10 OWF48920.1 - 0.58 10.7 3.3 7.5 7.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Nup54 PF13874.6 OWF48920.1 - 1.2 9.3 5.0 3.4 7.8 2.0 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 GvpK PF05121.12 OWF48920.1 - 1.6 8.8 5.8 1.5 8.9 3.9 2.0 2 0 0 2 2 2 0 Gas vesicle protein K CR6_interact PF10147.9 OWF48920.1 - 3.2 7.4 5.7 13 5.4 0.1 2.3 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 CRAL_TRIO PF00650.20 OWF48921.1 - 5.4e-33 114.0 1.0 1.1e-32 113.0 1.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.26 OWF48921.1 - 2.5e-22 78.8 1.2 2e-21 75.9 0.1 2.3 2 0 0 2 2 2 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.6 OWF48921.1 - 6.7e-05 23.1 2.6 0.00035 20.8 1.2 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain ZapA PF05164.13 OWF48921.1 - 0.07 13.6 0.1 0.43 11.0 0.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapA MazG-like PF12643.7 OWF48922.1 - 1.3e-11 44.6 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 OWF48922.1 - 1.2e-06 28.6 0.1 2.7e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain TMEM154 PF15102.6 OWF48923.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 OWF48923.1 - 0.25 12.2 1.2 0.65 10.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF624 PF04854.14 OWF48923.1 - 0.78 9.9 4.1 16 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Lectin_C PF00059.21 OWF48923.1 - 0.8 10.5 12.3 11 6.8 0.4 4.0 2 2 0 2 2 2 0 Lectin C-type domain PRKG1_interact PF15898.5 OWF48924.1 - 0.037 14.9 0.8 0.037 14.9 0.8 4.9 1 1 4 5 5 5 0 cGMP-dependent protein kinase interacting domain DASH_Dad1 PF08649.10 OWF48924.1 - 0.74 10.0 5.5 0.4 10.9 0.7 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad1 RPW8 PF05659.11 OWF48924.1 - 4.2 7.0 19.1 4.8 6.9 9.0 4.4 4 1 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MIEAP PF16026.5 OWF48925.1 - 1.7e-30 106.7 0.0 2.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondria-eating protein MIEAP PF16026.5 OWF48926.1 - 7.6e-31 107.9 0.4 7.6e-31 107.9 0.4 2.2 2 1 0 2 2 2 1 Mitochondria-eating protein TSNAXIP1_N PF15739.5 OWF48926.1 - 0.0097 16.3 1.4 0.0097 16.3 1.4 2.1 3 0 0 3 3 3 1 Translin-associated factor X-interacting N-terminus GAS PF13851.6 OWF48926.1 - 0.041 13.2 10.4 0.11 11.9 10.4 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 OWF48926.1 - 0.62 10.3 13.1 1.2 9.3 12.1 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 OWF48926.1 - 9.6 5.5 7.9 18 4.5 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIEAP PF16026.5 OWF48927.1 - 9.5e-28 97.8 0.5 1.1e-27 97.5 0.5 1.0 1 0 0 1 1 1 1 Mitochondria-eating protein Neuraminidase PF18413.1 OWF48927.1 - 0.11 12.1 0.0 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Neuraminidase-like domain MIEAP PF16026.5 OWF48928.1 - 5.5e-30 105.1 0.2 5.5e-30 105.1 0.2 2.5 2 1 1 3 3 3 1 Mitochondria-eating protein Fungal_TACC PF12709.7 OWF48928.1 - 0.069 13.6 8.0 0.07 13.6 2.6 3.2 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Neuraminidase PF18413.1 OWF48928.1 - 0.11 12.1 3.5 3.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Neuraminidase-like domain FliD_N PF02465.18 OWF48928.1 - 0.6 10.8 10.4 6.9 7.4 0.2 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4094 PF13334.6 OWF48928.1 - 2.3 8.7 7.5 0.48 10.9 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Cortex-I_coil PF09304.10 OWF48928.1 - 2.3 8.5 9.7 8.2 6.7 3.4 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil MIEAP PF16026.5 OWF48929.1 - 2.2e-33 116.2 0.0 2.2e-33 116.2 0.0 2.6 2 1 0 2 2 2 1 Mitochondria-eating protein Uso1_p115_C PF04871.13 OWF48929.1 - 0.021 15.2 14.1 0.021 15.2 14.1 3.0 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region LMBR1 PF04791.16 OWF48929.1 - 0.46 9.3 7.8 0.65 8.8 7.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3847 PF12958.7 OWF48929.1 - 2.7 8.2 20.8 6.1 7.0 15.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) XhlA PF10779.9 OWF48929.1 - 3.9 7.8 11.4 1.9 8.8 2.8 3.1 3 0 0 3 3 3 0 Haemolysin XhlA AAA_13 PF13166.6 OWF48929.1 - 8 5.0 21.3 0.083 11.5 13.2 1.8 2 1 0 2 2 2 0 AAA domain 2-Hacid_dh_C PF02826.19 OWF48930.1 - 1.6e-54 184.0 0.0 2.1e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF48930.1 - 1e-27 96.4 0.0 1.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OWF48930.1 - 0.0005 20.3 0.0 0.00077 19.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 OWF48930.1 - 0.0013 19.1 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding IlvN PF07991.12 OWF48930.1 - 0.022 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OWF48930.1 - 0.024 15.2 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OWF48930.1 - 0.087 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4116 PF13475.6 OWF48930.1 - 0.095 12.4 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) 2-Hacid_dh_C PF02826.19 OWF48931.1 - 4.5e-40 136.9 0.0 5.2e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OWF48931.1 - 0.036 13.7 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Myelin_PLP PF01275.19 OWF48932.1 - 1.7e-46 159.0 17.2 1.9e-46 158.9 17.2 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF3810 PF12725.7 OWF48932.1 - 1.3 8.3 9.1 0.69 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) SNF PF00209.18 OWF48933.1 - 3.4e-203 676.1 40.7 1.3e-202 674.1 40.7 1.7 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family HSP70 PF00012.20 OWF48934.1 - 3.7e-14 51.8 0.0 1.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein OHCU_decarbox PF09349.10 OWF48935.1 - 2.1e-39 135.5 0.0 2.3e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase RhoGAP PF00620.27 OWF48936.1 - 2.6e-36 124.7 0.3 7.7e-36 123.2 0.3 1.8 1 0 0 1 1 1 1 RhoGAP domain START PF01852.19 OWF48936.1 - 9.4e-34 116.7 0.5 2.6e-33 115.2 0.5 1.8 1 0 0 1 1 1 1 START domain Arm PF00514.23 OWF48938.1 - 6.3e-40 134.0 11.4 8.1e-05 22.5 0.0 11.6 12 0 0 12 12 12 6 Armadillo/beta-catenin-like repeat EDR1 PF14381.6 OWF48938.1 - 4e-37 127.9 0.0 2.3e-36 125.4 0.0 2.3 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 OWF48938.1 - 1.5e-25 89.4 12.8 7.5e-06 26.2 0.0 6.3 3 2 2 6 6 6 5 HEAT repeats HEAT PF02985.22 OWF48938.1 - 3.5e-18 64.1 13.5 0.076 13.3 0.1 9.4 10 0 0 10 10 9 6 HEAT repeat HEAT_EZ PF13513.6 OWF48938.1 - 1.2e-16 60.8 10.6 0.11 13.0 0.2 9.2 8 1 1 9 9 9 5 HEAT-like repeat V-ATPase_H_C PF11698.8 OWF48938.1 - 1.9e-11 44.1 3.4 0.00047 20.2 0.0 5.5 3 1 3 6 6 6 4 V-ATPase subunit H Cnd1 PF12717.7 OWF48938.1 - 1.2e-09 38.5 15.3 0.021 14.8 0.1 6.1 3 2 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 OWF48938.1 - 3.6e-07 29.9 7.8 0.046 13.2 0.0 4.8 2 2 3 5 5 5 3 Armadillo-like V-ATPase_H_N PF03224.14 OWF48938.1 - 2.6e-06 27.0 2.0 0.26 10.6 0.6 3.9 1 1 2 3 3 3 2 V-ATPase subunit H NopRA1 PF16201.5 OWF48938.1 - 0.0037 16.9 0.4 7.2 6.1 0.0 4.4 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 OWF48938.1 - 0.0057 16.7 1.4 0.22 11.6 0.0 4.0 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 OWF48938.1 - 0.0074 15.4 2.3 0.0074 15.4 2.3 4.8 4 1 1 5 5 5 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 OWF48938.1 - 0.02 15.1 3.1 19 5.5 0.1 4.4 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 OWF48938.1 - 0.029 14.7 11.6 9.6 6.7 0.0 6.1 4 2 3 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF4407 PF14362.6 OWF48938.1 - 1.4 8.2 5.1 4.9 6.4 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MID_MedPIWI PF18296.1 OWF48938.1 - 5.8 6.6 7.9 1 9.1 3.9 1.7 2 0 0 2 2 2 0 MID domain of medPIWI Lig_chan PF00060.26 OWF48940.1 - 4.6e-39 133.6 0.6 7.1e-39 133.0 0.6 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF48940.1 - 3e-38 130.6 0.1 8.1e-38 129.2 0.1 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 OWF48940.1 - 2.6e-23 82.7 0.3 6.7e-23 81.3 0.3 1.6 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 OWF48940.1 - 8.3e-18 64.6 0.0 2.2e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF348 PF03990.14 OWF48942.1 - 0.00041 20.0 0.3 29 4.5 0.0 6.1 2 1 2 4 4 4 2 G5-linked-Ubiquitin-like domain DUF4853 PF16145.5 OWF48942.1 - 0.072 13.2 0.7 45 4.2 0.0 3.7 2 1 3 5 5 5 0 Domain of unknown function (DUF4853) YlmH_RBD PF17774.1 OWF48942.1 - 2.8 8.3 7.8 40 4.6 0.1 4.2 2 2 3 5 5 5 0 Putative RNA-binding domain in YlmH Lig_chan PF00060.26 OWF48943.1 - 4.6e-33 114.2 0.3 8.8e-33 113.2 0.3 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF48943.1 - 2.7e-32 111.3 0.0 5.5e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF48943.1 - 1.1e-14 54.4 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 OWF48943.1 - 1.5e-12 47.3 3.9 8.1e-12 44.9 3.9 1.9 1 1 0 1 1 1 1 Receptor family ligand binding region OAD_gamma PF04277.13 OWF48943.1 - 0.076 13.6 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Homeodomain PF00046.29 OWF48944.1 - 4.2e-21 74.6 4.0 7.3e-21 73.8 4.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF48944.1 - 0.054 13.4 0.3 0.13 12.2 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF658 PF04936.12 OWF48944.1 - 0.088 12.6 0.5 0.56 9.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF658) HTH_23 PF13384.6 OWF48944.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homeodomain PF00046.29 OWF48945.1 - 1.5e-22 79.2 5.4 2.7e-22 78.4 5.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 OWF48946.1 - 1.5e-19 69.5 3.9 2.6e-19 68.8 3.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF48946.1 - 0.008 16.1 0.6 0.015 15.2 0.6 1.4 1 0 0 1 1 1 1 Homeobox KN domain Ank_2 PF12796.7 OWF48947.1 - 3e-110 361.0 43.5 5.6e-16 58.9 0.1 10.4 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF48947.1 - 3.8e-84 276.1 21.5 1.9e-10 41.0 0.0 13.8 3 3 11 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 OWF48947.1 - 2.9e-63 207.7 35.0 2.8e-06 27.5 0.0 17.1 17 1 0 17 17 17 14 Ankyrin repeat Ank_5 PF13857.6 OWF48947.1 - 8.1e-60 198.1 33.7 1.1e-09 38.4 0.1 12.4 4 3 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF48947.1 - 1.7e-56 181.5 13.3 0.0012 19.2 0.0 17.5 17 0 0 17 17 17 14 Ankyrin repeat AAA_16 PF13191.6 OWF48947.1 - 3.5e-07 30.8 0.0 1.3e-06 29.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OWF48947.1 - 2.4e-06 27.6 0.9 1.3e-05 25.2 0.9 2.2 1 1 0 1 1 1 1 NACHT domain DUF4407 PF14362.6 OWF48948.1 - 0.42 9.9 5.2 0.72 9.1 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-B_box PF00643.24 OWF48949.1 - 3.5e-09 36.7 8.6 3.5e-09 36.7 8.6 4.4 4 1 1 5 5 4 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF48949.1 - 2e-06 27.6 9.5 2e-06 27.6 9.5 4.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF48949.1 - 2.3e-06 27.3 6.6 2.3e-06 27.3 6.6 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF48949.1 - 1.2e-05 25.6 9.3 1.2e-05 25.6 9.3 3.8 3 0 0 3 3 2 1 Ring finger domain NHL PF01436.21 OWF48949.1 - 1.6e-05 24.7 3.5 0.34 11.0 0.5 5.3 5 0 0 5 5 5 1 NHL repeat Prok-RING_4 PF14447.6 OWF48949.1 - 0.00011 22.0 7.4 0.00011 22.0 7.4 3.3 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF48949.1 - 0.00015 21.6 9.3 0.00015 21.6 9.3 3.9 2 1 1 3 3 2 1 zinc-RING finger domain SGL PF08450.12 OWF48949.1 - 0.00015 21.4 2.7 1.3 8.6 0.0 4.0 1 1 3 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4_2 PF13923.6 OWF48949.1 - 0.00017 21.4 9.7 0.00017 21.4 9.7 3.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DUF3583 PF12126.8 OWF48949.1 - 0.00049 19.7 0.1 0.00082 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-C3HC4_4 PF15227.6 OWF48949.1 - 0.00063 19.8 8.0 0.00063 19.8 8.0 4.0 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF48949.1 - 0.00077 19.4 8.2 0.00077 19.4 8.2 3.6 3 0 0 3 3 2 1 RING-type zinc-finger Not3 PF04065.15 OWF48949.1 - 0.001 18.6 4.6 0.0018 17.7 4.6 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component MCPsignal PF00015.21 OWF48949.1 - 0.0038 17.0 0.4 0.0073 16.1 0.4 1.4 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Reg_prop PF07494.11 OWF48949.1 - 0.0058 16.7 0.1 1 9.8 0.0 4.1 4 0 0 4 4 3 1 Two component regulator propeller Tropomyosin_1 PF12718.7 OWF48949.1 - 0.0069 16.5 3.3 0.015 15.4 3.3 1.7 1 0 0 1 1 1 1 Tropomyosin like Spc7 PF08317.11 OWF48949.1 - 0.0083 15.0 4.3 0.013 14.4 4.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4208 PF13907.6 OWF48949.1 - 0.04 14.4 3.0 0.15 12.5 3.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) FlxA PF14282.6 OWF48949.1 - 0.042 13.8 4.3 0.031 14.3 2.6 1.7 1 1 0 1 1 1 0 FlxA-like protein GrpE PF01025.19 OWF48949.1 - 0.18 11.4 2.7 0.32 10.6 2.7 1.4 1 0 0 1 1 1 0 GrpE DUF1192 PF06698.11 OWF48949.1 - 0.21 11.7 0.5 0.42 10.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) SKA2 PF16740.5 OWF48949.1 - 1.3 8.9 6.3 2.2 8.1 4.0 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Swi5 PF07061.11 OWF48949.1 - 1.5 8.9 6.8 1.6 8.9 3.9 2.3 2 0 0 2 2 2 0 Swi5 RecG_N PF17190.4 OWF48949.1 - 3 8.6 5.9 12 6.7 4.7 2.6 2 1 0 2 2 1 0 RecG N-terminal helical domain Pirin PF02678.16 OWF48950.1 - 2.2e-30 104.8 0.1 7.4e-30 103.1 0.1 1.8 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 OWF48950.1 - 4.9e-28 97.5 0.0 4.2e-27 94.5 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OWF48950.1 - 0.0021 17.7 5.5 0.019 14.7 2.0 2.7 3 1 0 3 3 3 1 Cupin domain Cupin_3 PF05899.12 OWF48950.1 - 0.0021 17.7 0.2 0.59 9.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Pirin PF02678.16 OWF48951.1 - 6.3e-32 109.8 0.2 2.7e-31 107.7 0.1 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 OWF48951.1 - 3.2e-31 107.8 0.0 1.1e-29 102.8 0.0 2.5 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OWF48951.1 - 0.037 13.8 2.0 0.68 9.7 0.3 2.9 3 0 0 3 3 3 0 Cupin domain Cupin_3 PF05899.12 OWF48951.1 - 0.054 13.2 0.1 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Tox-GHH PF15636.6 OWF48952.1 - 1.9e-28 98.2 2.0 4e-28 97.2 0.3 2.4 2 0 0 2 2 2 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin RHS_repeat PF05593.14 OWF48952.1 - 5.8e-17 61.8 24.4 0.0046 17.4 0.1 11.9 11 2 0 11 11 11 4 RHS Repeat NHL PF01436.21 OWF48952.1 - 3.8e-10 39.3 0.7 0.38 10.9 0.0 6.4 6 0 0 6 6 6 2 NHL repeat EGF_2 PF07974.13 OWF48952.1 - 2.2e-09 37.5 123.5 4.9e-05 23.6 12.4 7.8 8 0 0 8 8 8 6 EGF-like domain RHS PF03527.14 OWF48952.1 - 0.00046 19.9 0.0 0.0016 18.1 0.0 2.0 1 0 0 1 1 1 1 RHS protein CarboxypepD_reg PF13620.6 OWF48952.1 - 0.001 19.3 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF839 PF05787.13 OWF48952.1 - 0.015 14.5 0.3 0.14 11.2 0.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF839) CarbopepD_reg_2 PF13715.6 OWF48952.1 - 0.099 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 CarboxypepD_reg-like domain LIAS_N PF16881.5 OWF48954.1 - 8.8e-34 116.2 0.1 1.7e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OWF48954.1 - 2.4e-14 54.1 0.0 3.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily INT_SG_DDX_CT_C PF15300.6 OWF48954.1 - 0.16 11.8 0.2 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Methyltransf_11 PF08241.12 OWF48956.1 - 2.1e-14 53.9 0.0 6e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF48956.1 - 1.1e-11 45.2 0.0 3.1e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF48956.1 - 1.6e-09 37.8 0.0 8.2e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF48956.1 - 2e-06 28.4 0.2 5.1e-05 23.9 0.1 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF48956.1 - 9.6e-06 25.5 0.0 4.2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF48956.1 - 0.0003 20.2 0.0 0.00096 18.6 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OWF48956.1 - 0.0015 17.9 0.0 0.0089 15.3 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OWF48956.1 - 0.0017 17.4 0.0 0.012 14.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 OWF48956.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 OWF48956.1 - 0.015 14.9 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HNOBA PF07701.14 OWF48957.1 - 2.8e-59 200.2 4.4 1.3e-57 194.8 4.4 2.4 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 OWF48957.1 - 1.2e-57 194.5 0.0 2e-57 193.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 OWF48957.1 - 1.1e-53 181.6 0.0 1.8e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 OWF48958.1 - 6.7e-58 195.3 0.0 1e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OWF48958.1 - 2.9e-44 151.1 3.0 2e-42 145.1 3.0 2.3 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 OWF48958.1 - 8.7e-23 81.1 0.0 1.6e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Haem-NO-binding DUF3791 PF12668.7 OWF48958.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) 7tm_1 PF00001.21 OWF48959.1 - 3.8e-36 124.8 12.4 7.1e-36 123.9 12.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF48959.1 - 0.00072 19.4 10.8 0.29 10.8 0.1 3.0 2 1 0 2 2 2 2 Olfactory receptor DUF3671 PF12420.8 OWF48959.1 - 0.5 10.5 9.8 2.1 8.4 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function 7TM_GPCR_Srx PF10328.9 OWF48959.1 - 2.5 7.6 31.1 0.058 13.0 22.8 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Ribonuc_red_lgC PF02867.15 OWF48960.1 - 1.4e-189 631.0 0.0 2e-189 630.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OWF48960.1 - 1.3e-23 82.8 0.0 3.3e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OWF48960.1 - 2e-17 63.6 0.0 6.6e-17 61.9 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain LRR_6 PF13516.6 OWF48961.1 - 1.3e-25 87.2 18.1 0.00012 21.9 0.1 8.8 10 0 0 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.33 OWF48961.1 - 4.7e-09 35.6 0.1 3.9 8.4 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich Repeat EF-hand_8 PF13833.6 OWF48961.1 - 9.1e-07 28.6 3.2 1.1e-06 28.4 0.8 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF48961.1 - 1.9e-05 23.9 6.2 0.061 12.9 0.7 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OWF48961.1 - 2.4e-05 23.9 5.0 0.35 10.9 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 OWF48961.1 - 2.6e-05 24.6 5.4 5.4e-05 23.6 2.4 2.9 2 1 1 3 3 3 2 EF-hand domain pair LRR_4 PF12799.7 OWF48961.1 - 0.00014 22.1 6.6 0.11 12.9 0.1 5.4 3 3 2 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF48961.1 - 0.13 12.1 11.9 3.9 7.3 0.7 4.7 4 2 1 5 5 5 0 Leucine rich repeat EphA2_TM PF14575.6 OWF48962.1 - 0.019 15.9 0.0 0.027 15.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PhoR PF11808.8 OWF48962.1 - 0.052 14.0 0.2 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR FixQ PF05545.11 OWF48962.1 - 0.052 13.5 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ LapA_dom PF06305.11 OWF48962.1 - 0.082 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TraL PF07178.11 OWF48962.1 - 0.13 12.8 0.2 0.13 12.8 0.2 1.6 2 0 0 2 2 2 0 TraL protein CYYR1 PF10873.8 OWF48964.1 - 0.00071 20.1 3.1 0.00076 20.0 3.1 1.1 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 OWF48964.1 - 0.015 16.1 0.0 0.025 15.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sigma_reg_N PF13800.6 OWF48964.1 - 0.12 12.7 1.5 0.14 12.4 0.3 1.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Alpha-amylase PF00128.24 OWF48965.1 - 9.5e-14 51.7 0.0 2.6e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Str_synth PF03088.16 OWF48966.1 - 3.8e-07 30.1 12.9 2.6 8.2 0.0 7.6 1 1 7 9 9 9 4 Strictosidine synthase Synapsin_N PF10581.9 OWF48966.1 - 2.5e-06 27.3 23.2 18 5.4 0.0 12.7 10 4 5 15 15 15 1 Synapsin N-terminal BNR_6 PF15899.5 OWF48966.1 - 2.3e-05 24.0 0.3 2.4e+02 2.2 0.0 8.2 9 0 0 9 9 9 0 BNR-Asp box repeat Peptidase_M57 PF12388.8 OWF48966.1 - 0.0002 21.0 7.7 12 5.5 0.1 6.3 1 1 7 8 8 8 1 Dual-action HEIGH metallo-peptidase RcsD_ABL PF16359.5 OWF48966.1 - 0.00038 20.6 0.0 57 3.9 0.0 5.5 1 1 8 9 9 9 0 RcsD-ABL domain Toxin_4 PF00706.17 OWF48966.1 - 0.026 14.9 0.2 2.2e+02 2.3 0.0 5.4 4 3 3 7 7 7 0 Anenome neurotoxin RHINO PF15319.6 OWF48966.1 - 0.026 14.6 2.3 48 3.9 0.0 4.6 1 1 2 4 4 4 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Peptidase_M1_N PF17900.1 OWF48966.1 - 1.4 9.1 9.2 46 4.1 0.1 4.9 1 1 4 6 6 6 0 Peptidase M1 N-terminal domain DUF1639 PF07797.14 OWF48967.1 - 0.89 9.6 3.3 2.2 8.3 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Tyrosinase PF00264.20 OWF48968.1 - 5.1e-24 85.8 1.0 7.6e-12 46.0 0.1 2.9 2 1 1 3 3 3 2 Common central domain of tyrosinase Tyrosinase PF00264.20 OWF48969.1 - 8.5e-23 81.8 3.3 2.7e-11 44.2 0.3 2.7 2 1 1 3 3 3 2 Common central domain of tyrosinase PSD2 PF07624.11 OWF48969.1 - 0.00083 19.1 0.0 0.0098 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1585) Tyrosinase PF00264.20 OWF48970.1 - 4.5e-25 89.2 5.4 9.1e-12 45.7 0.5 3.0 2 1 1 3 3 3 2 Common central domain of tyrosinase TLD PF07534.16 OWF48971.1 - 9.2e-13 48.6 0.2 1.6e-11 44.6 0.0 2.6 2 1 0 2 2 2 1 TLD SLATT_6 PF18169.1 OWF48971.1 - 0.2 11.2 1.5 0.39 10.3 1.5 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 DHHC PF01529.20 OWF48972.1 - 2e-34 118.6 11.2 2e-34 118.6 11.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase EpsG PF14897.6 OWF48972.1 - 0.01 15.1 1.4 0.01 15.1 1.4 1.6 2 0 0 2 2 2 0 EpsG family zf-RING_UBOX PF13445.6 OWF48973.1 - 1.1e-09 38.2 7.2 1.1e-09 38.2 7.2 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF48973.1 - 2.7e-08 33.5 6.7 2.7e-08 33.5 6.7 4.2 4 1 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF48973.1 - 5.4e-08 32.9 9.1 5.4e-08 32.9 9.1 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF48973.1 - 3.2e-07 30.5 6.0 3.2e-07 30.5 6.0 3.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF48973.1 - 1e-06 28.5 5.5 1e-06 28.5 5.5 3.4 4 1 0 4 4 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF48973.1 - 4e-06 26.6 4.9 4e-06 26.6 4.9 3.9 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF48973.1 - 1.6e-05 24.9 3.8 1.6e-05 24.9 3.8 4.0 5 0 0 5 5 3 2 B-box zinc finger NHL PF01436.21 OWF48973.1 - 5.9e-05 22.9 1.3 0.099 12.7 0.1 4.0 4 0 0 4 4 3 1 NHL repeat zf-C3HC4_2 PF13923.6 OWF48973.1 - 9.3e-05 22.2 9.0 9.3e-05 22.2 9.0 4.3 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) SBBP PF06739.11 OWF48973.1 - 0.00015 21.6 0.5 0.00015 21.6 0.5 2.1 2 0 0 2 2 2 1 Beta-propeller repeat zf-Nse PF11789.8 OWF48973.1 - 0.024 14.5 3.0 0.079 12.8 3.0 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OWF48973.1 - 0.088 12.7 13.8 0.023 14.5 7.3 3.5 3 1 0 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF48973.1 - 0.12 12.2 4.4 0.81 9.5 4.4 2.6 1 0 0 1 1 1 0 RING-like zinc finger PHD_like PF12910.7 OWF48973.1 - 0.45 10.5 2.6 0.42 10.6 1.1 1.6 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system ALMT PF11744.8 OWF48973.1 - 1.3 7.8 4.6 1.9 7.2 4.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Syntaxin_2 PF14523.6 OWF48973.1 - 2.7 8.4 7.6 3 8.2 5.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein MFS_1 PF07690.16 OWF48975.1 - 2.4e-14 53.0 35.2 2.4e-14 53.0 35.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OWF48975.1 - 1.5 7.1 7.1 0.068 11.5 1.6 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector SSF PF00474.17 OWF48976.1 - 2e-39 135.6 22.7 2.6e-39 135.3 22.7 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4271 PF14093.6 OWF48976.1 - 0.2 11.5 10.9 4.8 7.0 3.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) Sigma_reg_N PF13800.6 OWF48976.1 - 2.8 8.3 4.8 2.4 8.5 0.1 3.2 4 0 0 4 4 4 0 Sigma factor regulator N-terminal SSF PF00474.17 OWF48977.1 - 1e-08 34.5 2.6 1.3e-08 34.2 2.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family TctB PF07331.11 OWF48977.1 - 0.075 13.3 7.5 0.1 12.9 7.5 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Tmemb_55A PF09788.9 OWF48977.1 - 0.1 11.6 1.4 0.13 11.3 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Ig_2 PF13895.6 OWF48978.1 - 2.7e-10 40.4 0.1 5.6e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 OWF48978.1 - 1.2e-08 35.4 1.5 1.2e-08 35.4 1.5 2.1 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF48978.1 - 6.5e-08 32.5 0.3 8.3e-06 25.8 0.3 2.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF48978.1 - 3.9e-05 23.7 1.0 0.0027 17.9 0.4 2.8 2 1 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 OWF48978.1 - 8.2e-05 22.6 0.1 0.00019 21.4 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF48978.1 - 0.0032 17.8 0.0 0.044 14.2 0.0 2.3 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Collagen PF01391.18 OWF48978.1 - 0.048 13.4 0.3 0.076 12.8 0.3 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ig_3 PF13927.6 OWF48980.1 - 1.2e-07 32.3 0.1 2.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF48980.1 - 2.2e-07 30.9 0.2 7.6e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 OWF48980.1 - 0.00029 21.0 0.2 0.00078 19.6 0.2 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF48981.1 - 1.2e-71 236.8 0.0 2.3e-15 56.4 0.0 6.3 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF48981.1 - 9.2e-63 208.8 20.7 2.5e-13 50.4 0.1 6.7 6 1 1 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 OWF48981.1 - 8.1e-42 141.4 16.0 2.8e-10 40.4 0.1 6.5 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 OWF48981.1 - 5.1e-37 125.9 20.9 1.3e-07 31.7 0.0 6.9 6 1 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 OWF48981.1 - 3.9e-13 49.5 15.8 0.0024 18.0 0.2 9.3 6 4 1 7 7 7 2 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF48981.1 - 1.3e-10 40.7 0.2 0.048 13.2 0.0 5.6 5 0 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 OWF48981.1 - 4.1e-05 23.5 18.8 1.1 9.4 0.0 7.0 7 2 0 7 7 7 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF48981.1 - 0.0019 18.2 0.1 6.2 7.0 0.0 4.1 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain DUF3458 PF11940.8 OWF48981.1 - 0.097 13.1 0.2 0.27 11.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold Gly-rich_Ago1 PF12764.7 OWF48984.1 - 0.2 12.4 3.3 0.25 12.1 3.3 1.1 1 0 0 1 1 1 0 Glycine-rich region of argonaut Lipase_GDSL_2 PF13472.6 OWF48986.1 - 0.0019 18.6 0.0 0.0021 18.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GAS2 PF02187.17 OWF48988.1 - 0.00052 20.0 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain NST1 PF13945.6 OWF48988.1 - 0.9 9.6 13.4 3.6 7.7 0.4 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator GAS2 PF02187.17 OWF48990.1 - 5.8e-05 23.1 0.7 0.0002 21.4 0.2 2.0 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain GAS2 PF02187.17 OWF48991.1 - 3e-05 24.0 0.1 0.0001 22.3 0.1 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Tube PF17212.3 OWF48992.1 - 0.91 9.6 8.2 10 6.2 0.2 3.5 1 1 4 5 5 5 0 Tail tubular protein DUF4195 PF13836.6 OWF48992.1 - 3.1 7.9 14.2 19 5.3 0.3 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4195) PAT1 PF09770.9 OWF48993.1 - 1.6e-10 40.0 24.2 1.2e-08 33.8 0.9 4.3 3 2 0 3 3 3 2 Topoisomerase II-associated protein PAT1 SAND PF01342.21 OWF48994.1 - 9.6e-28 95.7 0.1 2.3e-27 94.5 0.1 1.7 1 0 0 1 1 1 1 SAND domain Peptidase_M17 PF00883.21 OWF48994.1 - 0.0001 21.7 1.9 0.00017 21.0 1.9 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF1397 PF07165.11 OWF48995.1 - 0.045 13.2 0.2 0.075 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) INCENP_N PF12178.8 OWF48996.1 - 0.058 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal TPR_1 PF00515.28 OWF48997.1 - 6.7e-43 142.8 23.7 1.2e-09 37.5 0.2 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 OWF48997.1 - 4.9e-38 126.2 24.5 4.2e-07 29.6 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 OWF48997.1 - 1.5e-31 106.0 24.7 4.4e-05 23.4 0.1 9.6 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 OWF48997.1 - 9.5e-31 105.9 31.2 3.7e-09 36.7 0.9 6.4 2 2 3 5 5 5 5 Tetratricopeptide repeat DUF1736 PF08409.11 OWF48997.1 - 9.2e-30 102.5 1.9 2.3e-29 101.2 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_16 PF13432.6 OWF48997.1 - 1.2e-29 102.7 14.7 7.5e-08 32.9 0.1 5.6 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 OWF48997.1 - 1.3e-27 95.2 17.2 3.6e-07 29.7 0.2 8.6 4 3 5 9 9 9 7 TPR repeat TPR_17 PF13431.6 OWF48997.1 - 5.2e-22 76.6 21.1 0.00013 22.1 0.1 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 OWF48997.1 - 1.6e-19 68.9 16.3 0.00068 20.2 0.3 8.1 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 OWF48997.1 - 6.8e-19 66.5 22.9 0.0064 16.4 0.2 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_10 PF13374.6 OWF48997.1 - 7e-19 67.1 38.1 0.00052 19.8 0.1 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 OWF48997.1 - 3.3e-15 56.4 19.6 0.0003 21.2 0.8 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_4 PF07721.14 OWF48997.1 - 4.7e-09 36.0 3.3 5.7 7.9 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF48997.1 - 4.4e-07 30.1 15.2 0.016 15.8 0.5 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF48997.1 - 2.8e-05 24.3 13.2 0.079 13.2 1.9 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 OWF48997.1 - 0.00032 20.2 17.1 0.12 11.7 3.5 3.7 1 1 2 4 4 4 3 MalT-like TPR region TPR_3 PF07720.12 OWF48997.1 - 0.046 13.7 9.0 0.54 10.3 0.1 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat NARP1 PF12569.8 OWF48997.1 - 0.048 12.6 12.6 3.4 6.4 1.6 3.5 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 OWF48997.1 - 0.051 13.3 15.1 6.4 6.4 1.4 5.3 1 1 2 4 4 4 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 OWF48997.1 - 0.19 11.9 11.6 2 8.6 0.4 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 OWF48997.1 - 0.24 12.1 9.2 56 4.6 0.1 6.1 5 0 0 5 5 5 0 Sel1 repeat MIT PF04212.18 OWF48997.1 - 0.92 9.6 15.8 0.88 9.7 0.1 5.6 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 OWF48997.1 - 2.8 8.4 12.5 40 4.6 0.1 5.0 3 2 3 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 OWF48997.1 - 4.6 7.7 6.2 19 5.8 0.2 4.6 6 0 0 6 6 5 0 PPR repeat Pyr_redox_2 PF07992.14 OWF48998.1 - 3e-28 98.9 0.2 4.2e-14 52.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 OWF48998.1 - 1.1e-08 34.9 0.3 1.1e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 OWF48998.1 - 1.2e-05 25.3 0.1 0.28 11.2 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OWF48998.1 - 0.00013 21.3 4.6 0.059 12.6 0.1 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF48998.1 - 0.0027 18.2 0.5 0.46 11.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF48998.1 - 0.0057 15.8 0.1 0.097 11.8 0.1 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 OWF48998.1 - 0.011 14.8 3.4 0.41 9.7 0.0 2.9 4 0 0 4 4 4 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OWF48998.1 - 0.023 14.9 0.1 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF48998.1 - 0.036 13.6 0.2 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF48998.1 - 0.045 12.8 0.4 0.13 11.3 0.1 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein Insulin PF00049.18 OWF48999.1 - 1.7e-08 35.4 7.2 2.6e-07 31.6 5.0 2.6 2 1 0 2 2 2 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 OWF48999.1 - 0.04 13.9 2.7 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type PCNP PF15473.6 OWF49000.1 - 2.4e-37 129.1 10.4 3e-37 128.7 10.4 1.1 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family MOLO1 PF17175.4 OWF49001.1 - 1.9e-18 66.7 0.7 1e-17 64.3 0.1 2.1 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 Pkinase PF00069.25 OWF49002.1 - 0.00012 21.5 0.0 0.024 14.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49002.1 - 0.0076 15.6 0.1 0.26 10.5 0.0 2.7 1 1 2 3 3 3 1 Protein tyrosine kinase DUF4834 PF16118.5 OWF49004.1 - 0.11 13.4 0.0 0.22 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) WSK PF03832.13 OWF49004.1 - 0.12 12.1 0.9 0.3 10.8 0.9 1.7 1 0 0 1 1 1 0 WSK motif GAS2 PF02187.17 OWF49005.1 - 1.6e-18 66.6 0.4 3.2e-18 65.6 0.4 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 OWF49005.1 - 7e-12 45.5 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain GAS2 PF02187.17 OWF49007.1 - 0.0002 21.4 1.3 0.00022 21.3 0.3 1.6 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain GAS2 PF02187.17 OWF49008.1 - 0.00023 21.2 0.2 0.00069 19.7 0.2 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain dsrm PF00035.26 OWF49009.1 - 1.2e-44 150.8 8.4 5.8e-11 42.9 0.1 5.3 5 0 0 5 5 5 4 Double-stranded RNA binding motif DND1_DSRM PF14709.7 OWF49009.1 - 3.1e-10 40.2 23.4 0.00023 21.3 0.6 5.8 4 4 0 4 4 4 4 double strand RNA binding domain from DEAD END PROTEIN 1 RNase_T PF00929.24 OWF49009.1 - 1.1e-06 29.3 0.0 4.8e-06 27.2 0.0 2.3 1 0 0 1 1 1 1 Exonuclease Mur_ligase PF01225.25 OWF49009.1 - 1.5e-06 28.4 0.1 2.8 8.4 0.0 4.1 4 0 0 4 4 4 3 Mur ligase family, catalytic domain DUF5055 PF16478.5 OWF49009.1 - 0.0002 21.6 2.8 20 5.5 0.0 4.7 5 0 0 5 5 4 0 Domain of unknown function (DUF5055) Peptidase_M85 PF13678.6 OWF49009.1 - 0.00099 18.8 0.1 3.7 7.1 0.0 3.3 3 0 0 3 3 3 1 NFkB-p65-degrading zinc protease Dicer_dimer PF03368.14 OWF49009.1 - 0.0016 18.6 2.5 26 5.1 0.1 4.6 4 0 0 4 4 4 0 Dicer dimerisation domain SapB_2 PF03489.17 OWF49009.1 - 0.015 15.4 2.3 43 4.3 0.0 5.0 5 0 0 5 5 5 0 Saposin-like type B, region 2 DUF3905 PF13045.6 OWF49009.1 - 0.022 14.8 0.1 15 5.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3905) Pet20 PF08692.10 OWF49009.1 - 0.086 13.6 0.9 5.5 7.7 0.2 3.6 2 1 0 2 2 2 0 Mitochondrial protein Pet20 DUF4599 PF15371.6 OWF49009.1 - 0.086 13.4 0.7 5.2 7.7 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) CorC_HlyC PF03471.17 OWF49009.1 - 0.16 12.0 0.0 62 3.7 0.0 3.8 4 0 0 4 4 4 0 Transporter associated domain APG6_N PF17675.1 OWF49009.1 - 0.18 12.3 3.7 7.1 7.2 0.3 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF5039 PF16442.5 OWF49009.1 - 0.31 10.6 18.0 7.4 6.1 0.8 5.2 4 1 0 5 5 5 0 Domain of unknown function (DUF5039) DNA_Packaging PF11053.8 OWF49009.1 - 0.71 9.7 3.0 4.5 7.1 0.1 3.3 4 0 0 4 4 4 0 Terminase DNA packaging enzyme dsrm PF00035.26 OWF49010.1 - 5.9e-26 91.0 0.2 2.7e-12 47.2 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif RNase_T PF00929.24 OWF49010.1 - 1.7e-14 54.7 0.0 5.3e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Exonuclease DND1_DSRM PF14709.7 OWF49010.1 - 0.00017 21.8 6.6 0.034 14.4 1.0 3.1 2 2 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 OWF49010.1 - 0.011 15.8 0.5 2.4 8.4 0.1 2.9 2 0 0 2 2 2 0 Dicer dimerisation domain DNA_pol_A_exo1 PF01612.20 OWF49010.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease LIX1 PF14954.6 OWF49010.1 - 0.038 13.3 3.3 0.61 9.3 0.4 2.4 1 1 1 2 2 2 0 Limb expression 1 TYW3 PF02676.14 OWF49010.1 - 0.052 12.9 1.2 7.8 5.8 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase TYW3 DUF5055 PF16478.5 OWF49010.1 - 0.065 13.5 0.1 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5055) DUF4303 PF14136.6 OWF49010.1 - 0.12 12.1 1.5 12 5.6 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) Serum_albumin PF00273.20 OWF49010.1 - 0.48 10.2 5.4 8.6 6.1 0.5 2.6 2 0 0 2 2 2 0 Serum albumin family Bowman-Birk_leg PF00228.20 OWF49010.1 - 1.2 9.6 4.1 28 5.2 0.3 2.6 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family GCFC PF07842.12 OWF49011.1 - 4.2e-89 298.8 16.7 4.2e-89 298.8 16.7 2.0 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 OWF49011.1 - 2.6e-22 79.2 6.5 2.6e-22 79.2 6.5 2.2 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.23 OWF49011.1 - 8e-18 64.1 1.8 1.8e-17 62.9 1.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OWF49011.1 - 1.4e-05 25.1 0.6 5.8e-05 23.1 0.6 2.1 1 0 0 1 1 1 1 G-patch domain CENP-B_dimeris PF09026.10 OWF49011.1 - 1.8 9.0 5.0 1.2 9.6 0.8 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF3868 PF12984.7 OWF49013.1 - 0.00076 19.3 4.5 75 3.2 0.1 5.5 1 1 5 6 6 6 3 Domain of unknown function, B. Theta Gene description (DUF3868) ComGG PF14173.6 OWF49013.1 - 1.4 9.3 10.5 1.6e+02 2.8 0.1 5.2 1 1 5 6 6 6 0 ComG operon protein 7 ATP_bind_3 PF01171.20 OWF49016.1 - 0.1 12.4 3.1 15 5.3 0.1 3.3 2 1 1 3 3 3 0 PP-loop family PDE8 PF08629.10 OWF49016.1 - 0.59 10.2 3.4 44 4.2 0.0 3.9 4 0 0 4 4 4 0 PDE8 phosphodiesterase DUF3437 PF11919.8 OWF49016.1 - 1.9 8.5 4.7 33 4.5 0.5 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF3437) UPF0515 PF15135.6 OWF49019.1 - 3.7e-54 183.9 8.9 4.3e-54 183.7 8.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 UBA_4 PF14555.6 OWF49019.1 - 1.5e-05 24.7 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Zn-ribbon_8 PF09723.10 OWF49019.1 - 2 8.6 7.1 1.4 9.1 2.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Sulfotransfer_2 PF03567.14 OWF49020.1 - 1.2e-26 94.2 1.0 6.3e-23 82.0 0.2 2.4 2 0 0 2 2 2 2 Sulfotransferase family Fis1_TPR_N PF14852.6 OWF49021.1 - 0.035 13.8 0.3 1.8e+02 1.9 0.0 4.3 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 OWF49022.1 - 3.2e-09 37.5 0.0 3.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF49022.1 - 1.1e-08 35.3 0.0 1.3e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-CCCH PF00642.24 OWF49023.1 - 0.00034 20.4 3.2 0.00075 19.3 3.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF49023.1 - 0.0037 17.2 5.9 0.0073 16.3 5.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 OWF49023.1 - 0.064 13.1 3.8 0.12 12.2 3.8 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger Nexin_C PF08628.12 OWF49024.1 - 0.076 13.6 0.1 0.23 12.1 0.1 1.8 1 0 0 1 1 1 0 Sorting nexin C terminal DUF5340 PF17275.2 OWF49024.1 - 0.079 13.1 0.3 0.27 11.4 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5340) Sulfotransfer_1 PF00685.27 OWF49025.1 - 1.1e-42 146.4 2.0 7.9e-42 143.6 2.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF49025.1 - 1.3e-06 29.0 0.3 2.5e-05 24.8 0.2 2.2 1 1 0 2 2 2 1 Sulfotransferase family Crl PF07417.12 OWF49025.1 - 0.015 15.4 0.4 0.026 14.6 0.4 1.4 1 0 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl Arc_PepC_II PF06847.11 OWF49026.1 - 0.00033 21.1 2.9 20 5.8 0.1 5.4 2 1 2 5 5 5 1 Archaeal Peptidase A24 C-terminus Type II FARP PF01581.16 OWF49026.1 - 0.0036 17.5 79.6 52 5.0 0.3 18.8 19 0 0 19 19 19 0 FMRFamide related peptide family TES PF08034.11 OWF49026.1 - 0.016 15.5 4.6 13 6.2 0.1 4.5 1 1 4 6 6 6 0 Trematode eggshell synthesis protein GRAB PF10375.9 OWF49026.1 - 0.12 12.3 2.6 50 4.0 0.0 3.8 3 0 0 3 3 3 0 GRIP-related Arf-binding domain DUF2400 PF09674.10 OWF49026.1 - 5.1 7.0 7.6 13 5.7 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) TSP_C PF05735.12 OWF49028.1 - 9.8e-57 192.1 0.8 1.6e-56 191.4 0.8 1.4 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 OWF49028.1 - 8.4e-46 153.4 138.7 2e-11 43.4 10.7 10.8 7 3 2 9 9 9 7 Thrombospondin type 3 repeat F5_F8_type_C PF00754.25 OWF49028.1 - 3.2e-24 85.5 0.0 7e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_3 PF13385.6 OWF49028.1 - 3.3e-20 72.8 1.1 3.3e-20 72.8 1.1 2.9 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 OWF49028.1 - 3.3e-11 43.2 18.4 4.7e-08 33.1 6.8 7.3 5 1 2 7 7 6 3 Calcium-binding EGF domain EGF_3 PF12947.7 OWF49028.1 - 6.6e-11 42.2 47.9 8.6e-06 25.9 6.6 6.1 4 0 0 4 4 4 3 EGF domain Cadherin PF00028.17 OWF49028.1 - 1e-10 41.9 0.5 0.00039 20.8 0.0 3.2 3 0 0 3 3 3 2 Cadherin domain Ephrin_rec_like PF07699.13 OWF49028.1 - 2.5e-08 33.6 7.3 2.5e-08 33.6 7.3 8.1 7 1 1 8 8 6 2 Putative ephrin-receptor like cEGF PF12662.7 OWF49028.1 - 0.00065 19.6 2.1 0.00065 19.6 2.1 7.4 6 1 0 6 6 6 3 Complement Clr-like EGF-like Pentaxin PF00354.17 OWF49028.1 - 0.029 14.1 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Pentaxin family Sialidase PF02973.16 OWF49028.1 - 0.12 11.8 0.9 0.3 10.5 0.2 1.9 2 0 0 2 2 2 0 Sialidase, N-terminal domain LRR_8 PF13855.6 OWF49029.1 - 1.3e-77 255.4 78.5 1.2e-09 37.8 3.5 15.4 7 6 9 17 17 17 15 Leucine rich repeat TSP_C PF05735.12 OWF49029.1 - 5.8e-61 205.9 2.4 1.3e-60 204.7 2.4 1.7 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 OWF49029.1 - 2.6e-44 148.6 136.9 1.6e-12 46.8 10.9 10.3 8 2 2 10 10 10 7 Thrombospondin type 3 repeat LRR_5 PF13306.6 OWF49029.1 - 6.2e-33 113.5 38.2 8.3e-09 35.5 2.7 7.4 3 1 5 8 8 8 7 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF49029.1 - 1.3e-28 98.6 85.0 0.00046 20.5 1.0 15.2 9 3 6 16 16 16 11 Leucine Rich repeats (2 copies) F5_F8_type_C PF00754.25 OWF49029.1 - 2.4e-24 85.9 2.4 9.3e-24 84.0 2.4 2.1 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_3 PF13385.6 OWF49029.1 - 3.5e-18 66.2 0.6 3.5e-18 66.2 0.6 3.5 4 0 0 4 4 3 1 Concanavalin A-like lectin/glucanases superfamily LRR_9 PF14580.6 OWF49029.1 - 6.7e-11 42.0 23.4 0.00056 19.4 0.8 6.5 4 2 2 6 6 6 5 Leucine-rich repeat EGF_CA PF07645.15 OWF49029.1 - 6.6e-10 39.0 23.5 1.6e-06 28.2 5.4 7.3 6 1 1 7 7 5 2 Calcium-binding EGF domain EGF_3 PF12947.7 OWF49029.1 - 5.2e-09 36.1 69.1 4.5e-06 26.8 8.1 5.9 5 0 0 5 5 4 3 EGF domain Cadherin PF00028.17 OWF49029.1 - 1.2e-07 32.1 0.9 4.8e-06 26.9 0.2 3.2 3 0 0 3 3 3 1 Cadherin domain Ephrin_rec_like PF07699.13 OWF49029.1 - 1.5e-06 27.9 5.3 1.5e-06 27.9 5.3 7.7 6 2 2 8 8 5 2 Putative ephrin-receptor like LRR_1 PF00560.33 OWF49029.1 - 0.00016 21.7 37.5 4.2 8.3 0.1 14.8 17 1 1 18 18 13 1 Leucine Rich Repeat cEGF PF12662.7 OWF49029.1 - 0.003 17.5 4.8 0.003 17.5 4.8 7.7 7 1 0 7 7 5 4 Complement Clr-like EGF-like fn3 PF00041.21 OWF49029.1 - 0.31 11.4 12.0 0.032 14.6 3.1 3.8 3 1 0 3 3 3 0 Fibronectin type III domain Actin PF00022.19 OWF49030.1 - 3.8e-141 470.4 0.0 4.3e-141 470.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OWF49030.1 - 0.16 10.8 0.2 11 4.8 0.0 2.6 2 1 1 3 3 3 0 MreB/Mbl protein Fz PF01392.22 OWF49031.1 - 5e-27 94.7 2.2 5e-27 94.7 2.2 1.6 2 0 0 2 2 2 1 Fz domain NTR PF01759.21 OWF49031.1 - 3.9e-10 39.5 1.7 9.5e-10 38.2 1.7 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module RAM PF15320.6 OWF49031.1 - 5.8 7.6 14.1 13 6.5 14.1 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein ADH_zinc_N PF00107.26 OWF49032.1 - 1.3e-25 89.9 0.3 2.2e-25 89.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF49032.1 - 6.3e-23 82.3 0.0 1.2e-22 81.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF49032.1 - 6.5e-09 35.6 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sulfotransfer_2 PF03567.14 OWF49033.1 - 3.2e-26 92.8 0.2 3.2e-24 86.2 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Nexin_C PF08628.12 OWF49033.1 - 0.052 14.1 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 Sorting nexin C terminal Ank_2 PF12796.7 OWF49034.1 - 1.9e-34 118.1 17.1 6e-11 42.8 0.2 10.5 3 2 7 11 11 11 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF49034.1 - 4.1e-31 106.9 11.2 0.013 16.1 0.0 14.2 14 2 3 17 17 15 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF49034.1 - 2.3e-21 75.6 7.0 9.2e-05 22.7 0.0 10.5 11 2 0 11 11 10 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF49034.1 - 4.7e-17 61.6 10.6 0.00088 19.6 0.0 11.6 12 0 0 12 12 11 2 Ankyrin repeat HEPN_DZIP3 PF18738.1 OWF49034.1 - 1.3e-14 54.1 0.1 1.3e-14 54.1 0.1 2.8 3 0 0 3 3 3 1 DZIP3/ hRUL138-like HEPN Ank_3 PF13606.6 OWF49034.1 - 3.9e-11 42.1 9.4 0.34 11.6 0.0 11.6 14 0 0 14 14 10 1 Ankyrin repeat ResIII PF04851.15 OWF49034.1 - 0.00044 20.3 0.4 0.0063 16.5 0.0 2.7 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 OWF49034.1 - 0.0097 15.4 0.1 0.078 12.5 0.0 2.5 2 1 1 3 3 3 1 P-loop containing dynein motor region NACHT PF05729.12 OWF49034.1 - 0.014 15.3 0.1 0.09 12.7 0.1 2.6 2 1 0 2 2 1 0 NACHT domain DUF2075 PF09848.9 OWF49034.1 - 0.015 14.5 0.2 0.042 13.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 OWF49034.1 - 0.016 15.3 0.1 0.049 13.7 0.1 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 OWF49034.1 - 0.023 15.1 0.0 0.11 12.9 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OWF49034.1 - 0.024 14.9 0.1 0.18 12.1 0.0 2.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 OWF49034.1 - 0.034 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OWF49034.1 - 0.083 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 OWF49034.1 - 0.087 12.4 0.0 0.32 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OWF49034.1 - 0.092 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 OWF49034.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Condensin2nSMC PF12422.8 OWF49034.1 - 0.13 12.5 0.6 0.95 9.6 0.6 2.6 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit APS_kinase PF01583.20 OWF49034.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.23 OWF49034.1 - 0.18 11.9 0.5 2.2 8.3 0.1 3.1 2 1 1 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4186 PF13811.6 OWF49034.1 - 0.2 11.7 1.6 0.72 9.9 0.2 2.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4186) AAA_18 PF13238.6 OWF49034.1 - 0.48 11.0 4.0 1.3 9.6 0.0 3.6 4 0 0 4 4 2 0 AAA domain DED PF01335.21 OWF49034.1 - 6.5 7.1 7.4 1.4 9.3 0.0 3.9 5 0 0 5 5 2 0 Death effector domain Lectin_C PF00059.21 OWF49035.1 - 1.5e-05 25.7 3.6 1.5e-05 25.7 3.6 2.5 2 1 0 2 2 2 1 Lectin C-type domain Macoilin PF09726.9 OWF49035.1 - 0.06 11.9 13.3 0.07 11.7 13.3 1.1 1 0 0 1 1 1 0 Macoilin family Mitofilin PF09731.9 OWF49035.1 - 0.16 10.7 11.3 0.2 10.4 11.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein KIAA1328 PF15369.6 OWF49035.1 - 4.6 7.0 13.6 6.9 6.4 13.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 DUF4757 PF15949.5 OWF49035.1 - 7.6 7.0 14.8 0.54 10.7 5.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4757) DUF5435 PF17503.2 OWF49035.1 - 7.6 6.2 15.3 7.8 6.2 13.8 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5435) UPF0449 PF15136.6 OWF49036.1 - 0.27 11.7 5.9 29 5.2 0.1 4.0 1 1 3 4 4 4 0 Uncharacterised protein family UPF0449 SIP PF04954.13 OWF49036.1 - 0.52 10.8 1.5 81 3.8 0.0 3.6 1 1 4 5 5 5 0 Siderophore-interacting protein GSH-S_ATP PF02955.16 OWF49037.1 - 0.047 13.1 7.3 4.1 6.8 0.2 2.9 1 1 2 3 3 3 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF645 PF04875.12 OWF49037.1 - 0.32 11.1 3.0 63 3.7 0.1 4.3 1 1 4 5 5 5 0 Protein of unknown function, DUF645 Urease_linker PF18473.1 OWF49037.1 - 0.55 10.2 16.8 11 6.0 0.2 5.2 3 2 2 5 5 5 0 Urease subunit beta-alpha linker domain DNA_pol_B_3 PF08408.10 OWF49037.1 - 1.1 9.5 10.3 1.7 8.9 3.1 2.1 1 1 1 2 2 2 0 DNA polymerase family B viral insert TFR_dimer PF04253.15 OWF49038.1 - 9e-31 106.5 0.0 1.7e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OWF49038.1 - 3.7e-21 75.7 0.0 2.6e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 OWF49038.1 - 1.8e-11 43.9 0.0 4.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OWF49038.1 - 0.0027 17.4 0.0 0.0094 15.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 HbrB PF08539.11 OWF49039.1 - 2.8e-08 33.9 1.3 1.9e-06 28.0 0.0 2.5 1 1 1 2 2 2 2 HbrB-like Serpin PF00079.20 OWF49040.1 - 3.7e-117 391.8 0.0 4.1e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FBPase PF00316.20 OWF49040.1 - 0.016 14.7 0.1 0.073 12.5 0.0 2.0 2 0 0 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain BIR PF00653.21 OWF49041.1 - 7.5e-36 122.6 0.5 3.7e-18 66.0 0.2 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 OWF49041.1 - 0.0076 16.3 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like DoxX_2 PF13564.6 OWF49042.1 - 3.1e-13 49.7 1.2 3.8e-13 49.4 1.2 1.1 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 OWF49042.1 - 5.4e-06 26.9 0.9 9.2e-06 26.2 0.9 1.3 1 0 0 1 1 1 1 DoxX DoxX_2 PF13564.6 OWF49043.1 - 9e-07 29.0 2.5 1.9e-06 27.9 2.5 1.5 1 1 0 1 1 1 1 DoxX-like family Sua5_yciO_yrdC PF01300.18 OWF49044.1 - 1.2e-41 142.1 0.0 1.5e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination Radical_SAM PF04055.21 OWF49045.1 - 2.7e-31 109.2 0.0 5.5e-29 101.7 0.0 2.5 2 0 0 2 2 2 2 Radical SAM superfamily UPF0004 PF00919.20 OWF49045.1 - 4e-30 103.7 1.2 9.1e-30 102.6 1.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 OWF49045.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Peptidase_C14 PF00656.22 OWF49046.1 - 1.3e-17 64.6 0.0 3.3e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 Caspase domain TatD_DNase PF01026.21 OWF49047.1 - 2.3e-42 145.1 0.0 2.7e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase BTB_2 PF02214.22 OWF49048.1 - 3.3e-17 62.6 0.1 5.5e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 OWF49048.1 - 0.002 18.2 0.0 0.0044 17.1 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain Tra_M PF05261.11 OWF49049.1 - 0.0031 17.5 0.8 1.5 8.8 0.0 2.9 1 1 2 3 3 3 2 TraM protein, DNA-binding LSPR PF06049.12 OWF49049.1 - 0.019 14.7 3.4 79 3.8 0.0 4.9 5 0 0 5 5 5 0 Coagulation Factor V LSPD Repeat DUF3552 PF12072.8 OWF49049.1 - 0.031 13.7 4.1 0.93 8.9 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Hyd_WA PF06462.12 OWF49051.1 - 0.0045 17.0 18.1 38 4.4 1.5 8.7 1 1 3 4 4 4 1 Propeller Thg1C PF14413.6 OWF49051.1 - 0.057 13.6 0.5 10 6.3 0.5 3.8 1 1 0 1 1 1 0 Thg1 C terminal domain DUF2627 PF11118.8 OWF49051.1 - 1.3 9.6 13.9 3.9e+03 -1.5 13.0 3.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) DciA PF05258.12 OWF49052.1 - 6.7e-05 23.2 0.8 7.2 7.1 0.1 4.9 3 2 2 5 5 5 2 Dna[CI] antecedent, DciA Perilipin PF03036.16 OWF49052.1 - 0.33 9.9 0.0 9.9 5.1 0.0 2.6 3 0 0 3 3 3 0 Perilipin family DUF969 PF06149.12 OWF49052.1 - 0.97 8.8 6.1 12 5.2 0.1 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF969) HAGH_C PF16123.5 OWF49053.1 - 2.1e-19 69.8 0.3 4e-19 68.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OWF49053.1 - 3.8e-12 46.6 0.3 9.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OWF49053.1 - 0.0027 17.3 0.6 0.0058 16.2 0.6 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SoDot-IcmSS PF16848.5 OWF49054.1 - 0.0003 20.8 32.2 2.5 8.0 0.1 10.1 2 2 9 12 12 12 6 Substrate of the Dot/Icm secretion system, putative AvrM_N PF18247.1 OWF49054.1 - 0.0014 18.5 22.4 1.4e+02 2.5 0.1 12.8 4 3 13 20 20 20 0 Flax-rust effector AvrM N-terminal domain 7tm_1 PF00001.21 OWF49055.1 - 1.5e-44 152.3 23.6 2.1e-44 151.8 23.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49055.1 - 3.6e-08 33.1 19.0 5.2e-08 32.6 19.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srd PF10317.9 OWF49055.1 - 0.034 13.3 23.0 0.45 9.7 22.8 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF445 PF04286.12 OWF49056.1 - 0.00045 20.1 3.6 0.00052 19.9 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Cas_Cas2CT1978 PF09707.10 OWF49056.1 - 0.018 15.1 0.1 10 6.3 0.0 3.5 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) MeMO_Hyd_G PF02964.16 OWF49056.1 - 0.043 13.8 1.3 3.6 7.6 0.1 3.2 1 1 2 3 3 3 0 Methane monooxygenase, hydrolase gamma chain T2SSM_b PF10741.9 OWF49056.1 - 0.12 12.1 0.1 8.5 6.2 0.0 2.8 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b MBD_C PF14048.6 OWF49056.1 - 0.18 12.5 4.1 1.4 9.7 0.1 3.4 1 1 3 4 4 4 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF3201 PF11447.8 OWF49056.1 - 0.19 11.2 3.5 3.6 7.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3201) DUF3198 PF11433.8 OWF49056.1 - 0.42 10.5 6.0 12 5.9 0.2 4.5 3 2 3 6 6 6 0 Protein of unknown function (DUF3198) MutL PF13941.6 OWF49056.1 - 0.82 8.2 5.5 3.1 6.3 1.2 2.2 1 1 1 2 2 2 0 MutL protein DUF1360 PF07098.11 OWF49056.1 - 1.3 9.1 6.0 15 5.6 0.2 3.9 1 1 5 6 6 6 0 Protein of unknown function (DUF1360) Imm3 PF14425.6 OWF49056.1 - 3.6 7.7 8.6 8.4 6.5 3.2 2.6 1 1 1 2 2 2 0 Immunity protein Imm3 Cas_Cas2CT1978 PF09707.10 OWF49057.1 - 4.6e-05 23.4 0.2 2 8.5 0.0 4.1 1 1 2 3 3 3 2 CRISPR-associated protein (Cas_Cas2CT1978) FliG_C PF01706.16 OWF49057.1 - 0.00081 19.5 0.1 1 9.6 0.0 2.6 1 1 2 3 3 3 3 FliG C-terminal domain DREV PF05219.12 OWF49057.1 - 0.0029 16.7 10.8 0.3 10.2 3.4 3.1 1 1 2 3 3 3 2 DREV methyltransferase DUF3198 PF11433.8 OWF49057.1 - 0.0089 15.9 3.7 2.5 8.1 0.0 4.6 2 2 3 5 5 5 1 Protein of unknown function (DUF3198) DUF3510 PF12022.8 OWF49057.1 - 0.022 15.1 8.7 0.23 11.8 1.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) 5-FTHF_cyc-lig PF01812.20 OWF49057.1 - 0.086 12.7 1.3 8.9 6.1 0.2 2.7 1 1 1 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family Nop52 PF05997.12 OWF49057.1 - 0.57 9.9 4.1 0.84 9.4 1.7 2.0 1 1 1 2 2 2 0 Nucleolar protein,Nop52 SspH PF08141.12 OWF49057.1 - 1.3 9.2 12.3 15 5.8 0.5 4.3 2 2 3 5 5 5 0 Small acid-soluble spore protein H family PRRSV_2b PF07069.11 OWF49057.1 - 1.7 9.2 11.1 40 4.8 0.6 5.0 1 1 6 7 7 7 0 Porcine reproductive and respiratory syndrome virus 2b NleF_casp_inhib PF16809.5 OWF49057.1 - 4.2 7.3 26.3 3.1 7.7 4.4 3.1 1 1 2 3 3 3 0 NleF caspase inhibitor 7tm_1 PF00001.21 OWF49058.1 - 6e-18 65.1 10.3 2e-09 37.1 3.1 2.4 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) DHHC PF01529.20 OWF49058.1 - 0.56 10.3 11.9 0.11 12.5 2.3 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase 7tm_1 PF00001.21 OWF49060.1 - 7.7e-50 169.7 19.5 1.3e-49 168.9 19.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49060.1 - 1.2e-07 31.4 16.1 2.4e-07 30.4 16.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Plasmodium_HRP PF05403.11 OWF49061.1 - 0.03 14.1 0.1 0.043 13.6 0.1 1.3 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Sir1 PF11603.8 OWF49062.1 - 0.3 11.6 7.1 14 6.2 0.1 3.8 1 1 3 4 4 4 0 Regulatory protein Sir1 Crisp PF08562.10 OWF49062.1 - 10 6.8 22.7 12 6.6 4.7 3.4 1 1 3 4 4 4 0 Crisp Sir1 PF11603.8 OWF49063.1 - 0.039 14.4 10.6 2 8.9 0.4 4.3 1 1 4 5 5 5 0 Regulatory protein Sir1 Ipi1_N PF12333.8 OWF49064.1 - 0.029 14.9 0.1 19 5.9 0.0 3.8 1 1 3 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DUF2267 PF10025.9 OWF49064.1 - 0.053 13.8 0.4 0.13 12.5 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) RisS_PPD PF16524.5 OWF49064.1 - 0.17 12.1 0.1 0.57 10.5 0.1 1.9 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS MazG PF03819.17 OWF49064.1 - 0.34 11.1 2.1 11 6.3 0.1 3.1 1 1 1 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Regnase_1_C PF18561.1 OWF49064.1 - 2.4 7.9 7.7 52 3.7 0.1 5.0 5 2 2 7 7 7 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain ATP-synt_ab PF00006.25 OWF49065.1 - 1.2e-61 208.1 0.0 1.7e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OWF49065.1 - 6.7e-21 74.6 1.0 1.4e-20 73.6 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 OWF49065.1 - 0.0022 17.3 0.4 0.0048 16.1 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 OWF49065.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OWF49065.1 - 0.032 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 OWF49065.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 OWF49065.1 - 0.057 13.8 0.0 0.88 10.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF49065.1 - 0.13 12.6 0.1 0.33 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 OWF49065.1 - 0.14 12.5 0.9 0.31 11.4 0.3 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OWF49065.1 - 0.17 12.3 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 OWF49065.1 - 0.19 12.2 0.1 0.41 11.1 0.1 1.5 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 OWF49065.1 - 0.22 10.7 0.1 0.59 9.3 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) bZIP_1 PF00170.21 OWF49066.1 - 3.2e-17 62.4 15.8 3.2e-17 62.4 15.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor pKID PF02173.17 OWF49066.1 - 1.2e-15 56.6 0.8 3.4e-15 55.2 0.8 1.8 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 OWF49066.1 - 1.1e-06 28.6 14.4 2.4e-06 27.5 14.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF49066.1 - 0.015 15.8 6.4 0.015 15.8 6.4 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor ASD2 PF08687.11 OWF49066.1 - 0.036 13.6 5.1 0.044 13.3 0.5 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DUF4988 PF16378.5 OWF49066.1 - 0.086 12.5 0.5 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function sCache_2 PF17200.4 OWF49066.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Single Cache domain 2 Rh5 PF18515.1 OWF49066.1 - 0.31 10.3 4.3 0.25 10.6 1.8 1.9 2 0 0 2 2 2 0 Rh5 coiled-coil domain NINJA_B PF16136.5 OWF49066.1 - 0.79 10.1 10.1 3.9 7.9 5.0 2.5 2 0 0 2 2 2 0 Putative nuclear localisation signal Phage_Gp23 PF10669.9 OWF49066.1 - 3.1 8.2 7.9 0.51 10.7 3.9 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4803 PF16061.5 OWF49068.1 - 1.8e-05 24.4 1.8 1 8.7 0.1 3.3 1 1 3 4 4 4 3 Domain of unknown function (DUF4803) Vault_2 PF17794.1 OWF49068.1 - 0.00018 21.8 0.1 0.97 9.9 0.0 4.7 3 3 1 5 5 5 1 Major Vault Protein repeat domain Laminin_I PF06008.14 OWF49068.1 - 0.00027 20.8 7.1 2.6 7.7 0.1 4.1 1 1 1 4 4 4 3 Laminin Domain I DUF3850 PF12961.7 OWF49068.1 - 0.00036 20.5 0.2 9.1 6.4 0.0 5.2 1 1 4 5 5 5 1 Domain of unknown function (DUF3850) DUF1803 PF08820.10 OWF49068.1 - 0.0041 17.1 4.2 21 5.2 0.1 5.3 1 1 3 5 5 5 1 Domain of unknown function (DUF1803) WYL PF13280.6 OWF49068.1 - 0.17 11.9 11.1 12 5.9 0.5 4.8 1 1 3 5 5 5 0 WYL domain DUF812 PF05667.11 OWF49068.1 - 1.1 8.1 8.3 41 2.9 0.0 4.8 3 3 1 5 5 5 0 Protein of unknown function (DUF812) CYYR1 PF10873.8 OWF49069.1 - 1.3e-06 28.9 19.7 1.3e-06 28.9 19.7 1.7 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Shisa PF13908.6 OWF49069.1 - 3.7e-06 27.3 2.6 3.7e-06 27.3 2.6 1.5 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF4719 PF15843.5 OWF49069.1 - 1.9e-05 24.9 3.3 3.2e-05 24.1 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4719) DUF998 PF06197.13 OWF49069.1 - 0.009 15.6 0.4 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF998) EphA2_TM PF14575.6 OWF49069.1 - 0.079 13.9 0.1 0.34 11.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 OWF49069.1 - 0.1 12.7 2.2 0.11 12.6 1.1 1.5 2 0 0 2 2 2 0 Podoplanin DUF485 PF04341.12 OWF49069.1 - 0.1 12.6 0.7 0.21 11.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Mid2 PF04478.12 OWF49069.1 - 0.35 10.7 2.9 0.73 9.7 2.9 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Neurensin PF14927.6 OWF49069.1 - 2.3 8.0 6.7 16 5.2 6.0 2.3 1 1 0 1 1 1 0 Neurensin DUF4690 PF15756.5 OWF49069.1 - 8 7.1 9.1 4.2 8.0 4.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Lipase_GDSL_2 PF13472.6 OWF49070.1 - 3.9e-05 24.1 0.0 5.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family C1q PF00386.21 OWF49072.1 - 7.4e-16 58.5 0.0 1.1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 C1q domain ADIP PF11559.8 OWF49072.1 - 0.005 16.9 3.2 0.0074 16.4 3.2 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 OWF49072.1 - 0.012 15.2 0.6 0.016 14.8 0.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 OWF49072.1 - 0.018 15.2 5.4 0.026 14.7 5.4 1.2 1 0 0 1 1 1 0 Tropomyosin like BclA_C PF18573.1 OWF49072.1 - 0.021 14.8 0.3 0.031 14.2 0.3 1.3 1 0 0 1 1 1 0 BclA C-terminal domain DUF641 PF04859.12 OWF49072.1 - 0.027 14.8 3.9 0.042 14.2 3.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 OWF49072.1 - 0.03 14.5 0.8 0.046 13.9 0.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 OWF49072.1 - 0.094 12.8 2.9 0.17 12.0 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3287 PF11690.8 OWF49072.1 - 0.68 9.7 6.7 0.14 11.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Noelin-1 PF12308.8 OWF49072.1 - 0.85 9.6 3.6 1.4 9.0 3.6 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein MetOD2 PF18548.1 OWF49072.1 - 1.7 8.8 5.9 3.9 7.6 0.6 2.2 1 1 1 2 2 2 0 Metanogen output domain 2 XhlA PF10779.9 OWF49072.1 - 2.9 8.2 5.0 6 7.1 5.0 1.5 1 0 0 1 1 1 0 Haemolysin XhlA C1q PF00386.21 OWF49073.1 - 3.7e-18 66.0 0.0 5.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 C1q domain Tropomyosin_1 PF12718.7 OWF49073.1 - 0.00073 19.7 3.3 0.0012 19.1 3.3 1.3 1 0 0 1 1 1 1 Tropomyosin like HrpB7 PF09486.10 OWF49073.1 - 0.03 14.7 2.1 0.048 14.0 2.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) BAR_3 PF16746.5 OWF49073.1 - 0.034 13.9 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 BAR domain of APPL family PC_rep PF01851.22 OWF49074.1 - 3.8e-25 87.0 11.5 3.3e-06 27.2 0.4 6.2 6 0 0 6 6 6 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OWF49074.1 - 4.4e-06 27.0 0.1 0.0023 18.3 0.0 3.8 4 0 0 4 4 4 1 HEAT repeats RPN1_RPN2_N PF17781.1 OWF49074.1 - 0.00014 21.4 0.9 0.00024 20.6 0.9 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain TRF PF08558.10 OWF49074.1 - 0.046 13.3 0.2 0.12 11.9 0.2 1.7 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Clathrin_H_link PF13838.6 OWF49074.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Clathrin-H-link HEAT PF02985.22 OWF49074.1 - 0.17 12.2 0.1 13 6.4 0.1 3.9 5 0 0 5 5 5 0 HEAT repeat 7tm_1 PF00001.21 OWF49075.1 - 1.1e-68 231.4 0.8 1.6e-68 230.9 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49075.1 - 3.2e-07 30.0 27.4 8.8e-07 28.6 15.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF49075.1 - 0.00086 19.1 6.4 0.00086 19.1 6.4 2.8 2 1 1 3 3 3 1 Olfactory receptor RPN2_C PF18004.1 OWF49076.1 - 3.6e-50 170.0 18.3 5.5e-50 169.4 18.3 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OWF49076.1 - 1.4e-11 44.2 0.9 8.8e-09 35.4 0.1 2.6 2 0 0 2 2 2 1 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OWF49076.1 - 2.4e-08 34.3 0.0 5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 OWF49076.1 - 2.3e-05 24.8 0.2 5.4e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 HEAT-like repeat Zip PF02535.22 OWF49076.1 - 0.00057 19.2 0.8 0.00082 18.7 0.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter TAF4 PF05236.14 OWF49076.1 - 0.0012 18.7 7.6 0.0016 18.2 7.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Cnd1 PF12717.7 OWF49076.1 - 0.003 17.6 0.2 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OWF49076.1 - 0.0057 16.8 0.2 1.4 9.4 0.0 3.0 3 0 0 3 3 2 1 HEAT repeat DDHD PF02862.17 OWF49076.1 - 0.046 13.9 3.6 0.067 13.4 3.6 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 OWF49076.1 - 0.046 12.5 8.4 0.062 12.1 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPL5 PF18168.1 OWF49076.1 - 0.091 12.0 6.0 0.14 11.4 6.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF2151 PF10221.9 OWF49076.1 - 0.11 11.1 9.4 0.14 10.7 9.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Vfa1 PF08432.10 OWF49076.1 - 0.12 12.6 27.2 0.18 12.1 27.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.8 OWF49076.1 - 0.16 10.8 22.6 0.23 10.4 22.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CENP-N PF05238.13 OWF49076.1 - 0.17 11.2 7.5 0.22 10.8 7.5 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like TT_ORF1 PF02956.14 OWF49076.1 - 0.21 10.2 0.9 0.29 9.7 0.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 Spore_coat_CotO PF14153.6 OWF49076.1 - 0.23 11.4 19.5 0.37 10.7 19.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO SID-1_RNA_chan PF13965.6 OWF49076.1 - 0.26 9.7 1.4 0.33 9.3 1.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rrn6 PF10214.9 OWF49076.1 - 0.54 8.7 4.8 0.68 8.4 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RR_TM4-6 PF06459.12 OWF49076.1 - 0.71 9.7 20.1 1.1 9.1 20.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.8 OWF49076.1 - 0.76 9.8 6.9 1.3 9.0 6.9 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DBINO PF13892.6 OWF49076.1 - 0.78 10.1 19.8 1.6 9.1 19.8 1.4 1 0 0 1 1 1 0 DNA-binding domain CDC45 PF02724.14 OWF49076.1 - 0.83 7.9 16.4 1.1 7.4 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 OWF49076.1 - 1.1 7.6 15.1 1.4 7.2 15.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FancD2 PF14631.6 OWF49076.1 - 1.2 6.5 15.4 1.6 6.1 15.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SLC12 PF03522.15 OWF49076.1 - 1.2 8.1 11.2 1.6 7.6 11.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 OWF49076.1 - 1.5 7.7 10.2 2.3 7.1 10.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 OWF49076.1 - 2 7.1 15.4 3 6.5 15.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cellulose_synt PF03552.14 OWF49076.1 - 2 6.8 7.9 2.8 6.3 7.9 1.1 1 0 0 1 1 1 0 Cellulose synthase TRAP_alpha PF03896.16 OWF49076.1 - 2.5 7.3 13.4 2.2 7.4 11.8 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit BPL_N PF09825.9 OWF49076.1 - 2.6 7.0 8.5 3.9 6.5 8.5 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Connexin PF00029.19 OWF49076.1 - 3.5 7.3 10.9 6.1 6.5 10.9 1.4 1 0 0 1 1 1 0 Connexin PA26 PF04636.13 OWF49076.1 - 3.8 6.3 7.2 5.2 5.9 7.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF262 PF03235.14 OWF49076.1 - 4.1 7.5 7.7 6.1 7.0 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Membralin PF09746.9 OWF49076.1 - 4.3 6.3 4.5 6 5.8 4.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein Afi1 PF07792.12 OWF49076.1 - 4.3 7.8 12.0 8.2 6.9 12.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DNA_pol_phi PF04931.13 OWF49076.1 - 4.6 5.2 19.5 6.6 4.7 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 OWF49076.1 - 4.6 6.5 19.5 6.8 6.0 19.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ALMT PF11744.8 OWF49076.1 - 5.1 5.8 10.6 8.7 5.0 10.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 OWF49076.1 - 6.6 5.4 14.8 9.3 4.9 14.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 OWF49076.1 - 8.9 5.0 14.2 13 4.4 14.2 1.2 1 0 0 1 1 1 0 Presenilin TP53IP5 PF15331.6 OWF49076.1 - 8.9 6.4 14.3 14 5.7 14.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF35_N PF12172.8 OWF49077.1 - 0.055 13.4 0.5 0.055 13.4 0.5 2.0 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 OWF49077.1 - 0.094 12.7 8.2 0.94 9.6 8.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 OWF49077.1 - 0.24 11.9 3.8 2.8 8.5 0.6 2.5 2 0 0 2 2 2 0 Cytochrome c3 NCD3G PF07562.14 OWF49077.1 - 0.24 11.4 9.7 0.52 10.3 2.4 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR zf-C3HC4_3 PF13920.6 OWF49077.1 - 0.26 11.2 9.0 2.2 8.2 1.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 OWF49077.1 - 0.28 10.8 10.9 0.69 9.5 1.0 2.3 2 0 0 2 2 2 0 RecR protein PHF5 PF03660.14 OWF49077.1 - 0.31 11.3 5.6 6.9 6.9 1.2 2.5 2 1 0 2 2 2 0 PHF5-like protein zinc_ribbon_15 PF17032.5 OWF49077.1 - 0.71 10.7 0.1 0.71 10.7 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbon family PLA2_B PF01735.18 OWF49078.1 - 1.9e-48 165.1 0.2 2.7e-37 128.3 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain C2 PF00168.30 OWF49078.1 - 2e-09 37.7 0.6 4.4e-09 36.5 0.6 1.6 1 0 0 1 1 1 1 C2 domain SNAPc19 PF15497.6 OWF49079.1 - 0.085 13.3 0.3 0.085 13.3 0.3 1.7 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 wnt PF00110.19 OWF49080.1 - 8e-109 363.9 21.3 9.3e-109 363.7 21.3 1.0 1 0 0 1 1 1 1 wnt family RhoGEF67_u1 PF16615.5 OWF49081.1 - 0.01 16.4 2.5 0.01 16.4 2.5 2.0 2 0 0 2 2 2 1 Unstructured region one on RhoGEF 6 and 7 Tetraspanin PF00335.20 OWF49082.1 - 0.0019 18.0 0.1 0.0024 17.7 0.1 1.1 1 0 0 1 1 1 1 Tetraspanin family GAPT PF11770.8 OWF49082.1 - 0.018 14.9 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Herpes_LAMP2 PF06126.11 OWF49082.1 - 0.19 10.3 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 LRR19-TM PF15176.6 OWF49082.1 - 0.37 10.8 3.0 2.5 8.1 3.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Mito_morph_reg PF14972.6 OWF49083.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator I-set PF07679.16 OWF49084.1 - 1.1e-20 73.5 1.6 2.2e-09 37.3 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF49084.1 - 8.2e-16 58.4 3.8 3.5e-07 30.7 1.1 2.8 3 0 0 3 3 2 2 Immunoglobulin domain V-set PF07686.17 OWF49084.1 - 8.4e-14 51.7 2.6 5.1e-06 26.6 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF49084.1 - 8.4e-12 45.3 2.7 1.5e-06 28.4 0.6 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 OWF49084.1 - 2.4e-08 34.0 8.3 0.0004 20.5 1.2 3.5 3 1 0 3 3 3 2 Immunoglobulin domain MMR_HSR1 PF01926.23 OWF49084.1 - 3.1e-08 33.7 0.1 6.5e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF49084.1 - 1.5e-07 31.5 1.5 9.2e-05 22.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Ig_6 PF18452.1 OWF49084.1 - 7.1e-05 22.3 0.0 0.57 9.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Septin PF00735.18 OWF49084.1 - 0.0002 20.7 0.5 0.00039 19.8 0.5 1.5 1 0 0 1 1 1 1 Septin AAA_23 PF13476.6 OWF49084.1 - 0.00051 20.6 1.0 0.00051 20.6 1.0 2.0 1 1 1 2 2 2 1 AAA domain Ig_5 PF16681.5 OWF49084.1 - 0.00064 20.1 5.0 0.063 13.7 1.1 3.4 2 2 1 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain G-alpha PF00503.20 OWF49084.1 - 0.00077 18.7 1.0 0.0016 17.7 0.1 1.9 2 0 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 OWF49084.1 - 0.00089 18.8 0.7 0.055 13.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B C2-set PF05790.15 OWF49084.1 - 0.001 19.2 1.6 3.3 8.0 0.0 3.6 4 0 0 4 4 3 2 Immunoglobulin C2-set domain IIGP PF05049.13 OWF49084.1 - 0.0023 17.0 0.3 0.005 15.9 0.0 1.6 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Ig_4 PF16680.5 OWF49084.1 - 0.0025 18.0 5.0 0.11 12.8 0.3 3.3 3 0 0 3 3 2 1 T-cell surface glycoprotein CD3 delta chain GTP_EFTU PF00009.27 OWF49084.1 - 0.0034 16.9 3.1 0.49 9.9 0.1 2.9 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OWF49084.1 - 0.016 15.3 4.5 0.13 12.3 0.1 2.9 2 1 1 3 3 3 0 Dynamin family AAA_29 PF13555.6 OWF49084.1 - 0.016 15.0 0.1 0.047 13.4 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 OWF49084.1 - 0.03 13.8 0.1 0.067 12.6 0.1 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 OWF49084.1 - 0.031 14.7 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AIG1 PF04548.16 OWF49084.1 - 0.063 12.6 0.1 0.063 12.6 0.1 2.6 2 1 1 3 3 3 0 AIG1 family Receptor_2B4 PF11465.8 OWF49084.1 - 0.07 13.3 0.1 2.7 8.2 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 OWF49084.1 - 0.082 12.9 4.9 1.2 9.1 0.3 3.2 1 1 0 2 2 2 0 CD47 immunoglobulin-like domain BIR PF00653.21 OWF49085.1 - 2.5e-13 50.5 0.3 3.9e-13 49.9 0.0 1.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Galactosyl_T PF01762.21 OWF49087.1 - 1.4e-35 122.9 0.6 2.4e-35 122.1 0.6 1.3 1 0 0 1 1 1 1 Galactosyltransferase CTD PF12815.7 OWF49088.1 - 5.5e-05 23.6 9.5 0.02 15.4 2.2 2.1 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Cyt-b5 PF00173.28 OWF49088.1 - 0.32 11.2 5.9 1.9 8.7 1.9 2.9 2 1 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Galactosyl_T PF01762.21 OWF49089.1 - 3.9e-81 271.5 0.5 1.1e-41 142.9 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 OWF49089.1 - 0.00044 19.8 0.9 0.0046 16.4 0.0 2.4 3 0 0 3 3 3 1 Fringe-like Galactosyl_T PF01762.21 OWF49090.1 - 4.4e-25 88.6 0.8 7.5e-25 87.9 0.8 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF49090.1 - 2.4e-05 23.9 0.8 5.4e-05 22.8 0.9 1.6 1 1 1 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OWF49091.1 - 1.7e-74 249.8 4.7 3.4e-40 138.0 0.4 2.2 2 0 0 2 2 2 2 Galactosyltransferase Galactosyl_T PF01762.21 OWF49092.1 - 4.4e-43 147.4 0.1 7.3e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF49092.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 1 0 1 1 1 1 Fringe-like Glycos_transf_2 PF00535.26 OWF49092.1 - 0.036 13.9 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Galactosyl_T PF01762.21 OWF49093.1 - 1.8e-46 158.5 0.2 6.9e-27 94.5 0.1 2.2 2 0 0 2 2 2 2 Galactosyltransferase Galactosyl_T PF01762.21 OWF49094.1 - 1.1e-68 230.9 3.3 1.9e-35 122.4 0.3 2.3 2 0 0 2 2 2 2 Galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF49094.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 SCHIP-1 PF10148.9 OWF49095.1 - 1.9e-72 243.7 5.7 1.9e-72 243.7 5.7 3.2 3 0 0 3 3 3 1 Schwannomin-interacting protein 1 IQCJ-SCHIP1 PF15157.6 OWF49095.1 - 1.1e-05 25.3 0.5 1.1e-05 25.3 0.5 3.4 4 0 0 4 4 4 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif IQ PF00612.27 OWF49095.1 - 9.5e-05 21.9 13.4 0.0016 18.1 0.2 2.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif EF-hand_13 PF17958.1 OWF49096.1 - 2.4e-37 126.6 0.0 1.4e-36 124.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OWF49096.1 - 3.9e-20 72.1 6.2 8.7e-19 67.8 0.7 4.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF49096.1 - 1e-05 24.7 2.0 0.016 14.7 0.1 4.7 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.6 OWF49096.1 - 1.4e-05 24.3 0.2 0.00027 20.3 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OWF49096.1 - 0.00057 19.6 3.3 0.03 14.3 0.0 4.3 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.6 OWF49096.1 - 0.058 13.3 1.7 0.25 11.2 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair MFS_1 PF07690.16 OWF49098.1 - 2.3e-25 89.3 46.7 1.5e-19 70.2 25.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.10 OWF49098.1 - 0.014 15.3 1.7 0.041 13.7 1.7 1.8 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 HRG PF16954.5 OWF49098.1 - 0.53 10.7 0.1 0.53 10.7 0.1 4.4 7 1 0 7 7 7 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Lipase PF00151.19 OWF49099.1 - 7.7e-88 295.0 0.2 1e-87 294.6 0.2 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 OWF49099.1 - 2.8e-06 28.1 1.0 4.8e-06 27.3 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 OWF49099.1 - 0.00014 21.4 0.3 0.00068 19.2 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 OWF49099.1 - 0.00096 18.9 0.2 0.0016 18.1 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OWF49099.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lbh PF15317.6 OWF49099.1 - 0.036 14.9 0.0 0.065 14.1 0.0 1.3 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein DUF676 PF05057.14 OWF49099.1 - 0.046 13.2 0.3 0.082 12.4 0.3 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OWF49099.1 - 0.1 11.8 1.2 0.16 11.2 1.2 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PTPRCAP PF15713.5 OWF49100.1 - 0.11 12.8 1.3 0.19 12.0 1.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Ribosomal_60s PF00428.19 OWF49100.1 - 8.5 7.0 7.5 19 5.9 7.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein GPHR_N PF12537.8 OWF49101.1 - 3.9 7.6 4.4 4.7 7.4 0.0 3.1 3 1 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal Sec34 PF04136.15 OWF49103.1 - 5.1e-48 162.7 6.8 5.1e-48 162.7 6.8 2.9 2 1 0 2 2 2 1 Sec34-like family DUF501 PF04417.12 OWF49103.1 - 0.015 15.1 0.0 0.054 13.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF2935 PF11155.8 OWF49103.1 - 0.039 14.3 0.2 0.79 10.1 0.2 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ACP53EA PF06313.11 OWF49103.1 - 0.055 13.7 1.9 3.2 8.0 0.1 2.9 2 0 0 2 2 2 0 Drosophila ACP53EA protein COX17 PF05051.13 OWF49103.1 - 0.098 13.0 2.7 9.2 6.7 0.2 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) PCI PF01399.27 OWF49104.1 - 1e-18 67.7 2.8 1.3e-18 67.5 1.7 1.7 2 0 0 2 2 2 1 PCI domain Lig_chan PF00060.26 OWF49105.1 - 2.2e-26 92.5 0.3 4.5e-26 91.5 0.2 1.6 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF49105.1 - 2.1e-23 82.7 0.0 4.7e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF49105.1 - 1.8e-14 53.7 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 OWF49105.1 - 0.7 9.9 4.6 0.2 11.6 1.1 2.0 2 0 0 2 2 2 0 Ion channel Ydr279_N PF17745.1 OWF49109.1 - 1.5e-11 44.4 0.0 2.4e-10 40.5 0.0 2.4 2 1 0 2 2 2 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 OWF49109.1 - 9.7e-10 38.9 0.5 2.2e-09 37.7 0.0 1.8 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ribosomal_L7Ae PF01248.26 OWF49110.1 - 5.5e-06 26.0 0.1 1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NupH_GANP PF16768.5 OWF49111.1 - 0.25 11.0 1.9 7.7 6.1 0.3 2.1 1 1 1 2 2 2 0 Nucleoporin homology of Germinal-centre associated nuclear protein KRTAP PF11759.8 OWF49111.1 - 0.68 10.5 53.7 8.2e+03 -2.6 23.6 3.8 1 1 1 2 2 2 0 Keratin-associated matrix LRR_8 PF13855.6 OWF49113.1 - 1e-26 92.4 36.9 4.6e-09 35.9 2.8 5.7 3 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 OWF49113.1 - 7.7e-14 51.6 33.6 0.00014 22.2 3.1 8.6 5 2 5 11 11 11 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF49113.1 - 1.6e-06 28.1 4.2 2.1e-05 24.5 1.1 2.9 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF49113.1 - 0.00073 19.1 8.5 0.029 13.9 1.6 3.1 2 2 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 OWF49113.1 - 0.092 13.3 27.2 2 9.3 0.1 10.0 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF49113.1 - 4.7 7.5 24.4 7.2 6.9 0.5 8.5 11 0 0 11 11 11 0 Leucine Rich repeat LRR_8 PF13855.6 OWF49114.1 - 9.8e-30 102.1 24.8 9.5e-10 38.1 1.3 6.4 4 2 2 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 OWF49114.1 - 1.4e-09 38.0 5.1 0.00029 20.8 1.3 4.2 2 2 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF49114.1 - 4.4e-09 36.5 33.1 0.016 15.6 3.0 7.7 4 4 1 7 7 7 5 Leucine Rich repeats (2 copies) LRRNT PF01462.18 OWF49114.1 - 0.00023 20.8 2.7 0.00023 20.8 2.7 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 OWF49114.1 - 0.00095 18.7 7.7 0.18 11.3 0.2 2.9 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 OWF49114.1 - 0.97 10.2 21.4 11 7.1 0.5 8.0 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 OWF49115.1 - 2.3e-21 75.3 33.7 3.4e-07 29.9 1.1 7.6 3 3 7 10 10 9 9 Leucine rich repeat LRR_4 PF12799.7 OWF49115.1 - 2.3e-17 62.8 37.9 8.3e-07 29.2 0.9 8.6 4 2 7 11 11 11 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF49115.1 - 7.5e-06 25.6 17.8 0.58 10.4 0.5 7.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_5 PF13306.6 OWF49115.1 - 0.00012 22.0 5.5 0.0055 16.7 0.3 3.8 1 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF49115.1 - 0.00015 21.8 20.1 24 6.0 0.0 9.4 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_9 PF14580.6 OWF49115.1 - 0.0091 15.5 12.8 0.36 10.3 0.5 3.6 2 1 2 4 4 4 3 Leucine-rich repeat DUF4089 PF13318.6 OWF49116.1 - 5.1e-15 55.7 0.0 26 5.4 0.0 11.4 2 2 12 15 15 15 0 Protein of unknown function (DUF4089) Cdc13_OB2 PF18691.1 OWF49116.1 - 2.9e-09 36.9 1.0 12 6.0 0.0 6.5 1 1 5 7 7 7 1 Cell division control protein 13, OB2 domain DUF5016 PF16408.5 OWF49116.1 - 0.001 19.1 13.3 23 5.0 0.1 8.2 1 1 8 10 10 10 0 Domain of unknown function (DUF5016) HU-CCDC81_bac_1 PF18174.1 OWF49116.1 - 0.0092 15.8 19.7 28 4.7 0.1 11.0 2 2 10 15 15 15 0 CCDC81-like prokaryotic HU domain 1 Tax PF02959.16 OWF49116.1 - 0.018 14.5 4.5 13 5.1 0.2 4.1 1 1 3 4 4 4 0 HTLV Tax LAGLIDADG_1 PF00961.19 OWF49116.1 - 0.18 12.8 6.0 17 6.4 0.0 4.0 1 1 2 3 3 3 0 LAGLIDADG endonuclease DnaB PF00772.21 OWF49116.1 - 0.3 11.2 8.6 19 5.4 0.1 4.4 4 2 0 4 4 4 0 DnaB-like helicase N terminal domain UBA_e1_thiolCys PF10585.9 OWF49116.1 - 0.36 10.7 0.7 79 3.0 0.0 3.6 2 2 2 4 4 4 0 Ubiquitin-activating enzyme active site MDD_C PF18376.1 OWF49116.1 - 6.1 6.5 10.2 9.8 5.9 0.8 3.9 1 1 3 4 4 4 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain LRR_8 PF13855.6 OWF49117.1 - 7.7e-18 64.0 32.6 3.9e-08 32.9 1.8 6.6 3 3 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OWF49117.1 - 3e-14 52.9 33.9 0.00063 20.1 3.1 8.5 3 2 8 11 11 11 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF49117.1 - 6.2e-06 26.2 8.8 4e-05 23.6 3.8 3.4 3 2 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF49117.1 - 0.00011 22.3 19.1 3.3 8.6 0.2 10.3 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_9 PF14580.6 OWF49117.1 - 0.0064 16.0 4.1 0.03 13.8 1.9 2.6 1 1 1 2 2 2 2 Leucine-rich repeat DoxA PF07680.11 OWF49117.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 TQO small subunit DoxA TPKR_C2 PF16920.5 OWF49117.1 - 0.078 13.1 0.2 0.078 13.1 0.2 2.7 3 0 0 3 3 3 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 OWF49117.1 - 0.32 11.2 34.1 0.55 10.4 0.2 9.6 10 0 0 10 10 10 0 Leucine Rich repeat DUF1610 PF07754.11 OWF49118.1 - 1.5e-07 31.2 1.1 4.1e+02 1.1 0.0 15.1 14 0 0 14 14 14 0 Domain of unknown function (DUF1610) Tfb5 PF06331.12 OWF49118.1 - 0.02 14.9 19.5 26 4.9 0.1 8.3 1 1 3 4 4 4 0 Transcription factor TFIIH complex subunit Tfb5 Coq4 PF05019.13 OWF49118.1 - 0.032 13.6 82.6 4.5 6.5 2.7 9.2 1 1 13 14 14 14 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Galactosyl_T PF01762.21 OWF49119.1 - 1.1e-32 113.5 1.3 1.2e-32 113.3 1.3 1.0 1 0 0 1 1 1 1 Galactosyltransferase AAA_11 PF13086.6 OWF49122.1 - 6.4e-16 58.9 4.1 1.5e-15 57.7 4.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF49122.1 - 6.6e-06 26.5 0.0 1.4e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OWF49122.1 - 0.00042 19.7 0.0 0.00078 18.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OWF49122.1 - 0.00043 20.1 0.3 0.00095 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF49122.1 - 0.0021 18.3 0.2 0.0078 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OWF49122.1 - 0.0048 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 OWF49122.1 - 0.0063 16.9 0.3 0.033 14.6 0.3 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 OWF49122.1 - 0.008 16.0 0.0 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 OWF49122.1 - 0.012 16.1 0.0 0.036 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 OWF49122.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 OWF49122.1 - 0.013 15.2 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OWF49122.1 - 0.02 15.4 0.0 0.11 13.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain Sod_Ni PF09055.11 OWF49122.1 - 0.02 15.4 2.6 0.031 14.9 0.4 2.2 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase AAA_5 PF07728.14 OWF49122.1 - 0.027 14.5 0.0 0.1 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OWF49122.1 - 0.041 13.8 0.2 0.19 11.6 0.0 2.2 3 0 0 3 3 3 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OWF49122.1 - 0.049 13.4 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OWF49122.1 - 0.081 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 OWF49122.1 - 0.094 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF424 PF04242.13 OWF49123.1 - 9.5e-06 25.8 10.4 0.039 14.2 1.5 3.8 1 1 2 3 3 3 3 Protein of unknown function (DUF424) HTH_45 PF14947.6 OWF49123.1 - 1.9e-05 24.5 29.3 0.31 11.1 4.7 6.0 1 1 5 6 6 6 5 Winged helix-turn-helix DUF4385 PF14328.6 OWF49123.1 - 0.0025 17.9 8.1 2.5 8.2 0.2 4.5 1 1 4 5 5 5 2 Domain of unknown function (DUF4385) RNR_N PF08343.10 OWF49123.1 - 0.019 15.0 13.9 6.8 6.8 0.8 4.6 1 1 3 4 4 4 0 Ribonucleotide reductase N-terminal Prefoldin_3 PF13758.6 OWF49123.1 - 0.52 10.4 10.5 4.5 7.4 0.9 3.6 1 1 3 4 4 4 0 Prefoldin subunit AstB PF04996.12 OWF49123.1 - 2.7 6.6 4.8 13 4.3 4.3 2.2 1 1 0 1 1 1 0 Succinylarginine dihydrolase DUF3562 PF12085.8 OWF49124.1 - 0.11 12.1 11.9 27 4.4 0.0 7.4 5 2 4 9 9 9 0 Protein of unknown function (DUF3562) zf-PHD-like PF15446.6 OWF49124.1 - 0.21 11.2 8.7 18 4.9 0.1 4.9 1 1 2 5 5 5 0 PHD/FYVE-zinc-finger like domain RNR_N PF08343.10 OWF49124.1 - 1.7 8.7 27.2 32 4.7 0.8 7.5 1 1 8 9 9 9 0 Ribonucleotide reductase N-terminal DUF424 PF04242.13 OWF49125.1 - 0.00015 22.0 2.9 0.027 14.7 0.5 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF424) DUF3258 PF11646.8 OWF49125.1 - 0.069 13.3 3.1 11 6.2 0.8 3.4 1 1 1 2 2 2 0 Protein of unknown function DUF3258 RNR_N PF08343.10 OWF49125.1 - 0.093 12.8 4.8 1.4 9.0 0.3 2.8 1 1 1 2 2 2 0 Ribonucleotide reductase N-terminal HERV-K_REC PF15695.5 OWF49125.1 - 0.3 11.2 9.4 2.3 8.3 0.2 3.6 1 1 3 4 4 4 0 Rec (regulator of expression encoded by corf) of HERV-K-113 DUF3562 PF12085.8 OWF49125.1 - 0.33 10.6 1.7 24 4.6 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3562) ILEI PF15711.5 OWF49125.1 - 0.34 11.4 9.3 2.7 8.6 0.4 3.0 1 1 3 4 4 4 0 Interleukin-like EMT inducer Cdc13_OB4_dimer PF18233.1 OWF49125.1 - 0.87 9.7 20.5 3.9 7.7 2.1 3.7 1 1 3 4 4 4 0 Cdc13 OB4 dimerization domain HTH_45 PF14947.6 OWF49125.1 - 0.89 9.6 14.6 0.29 11.1 2.7 3.1 1 1 3 4 4 4 0 Winged helix-turn-helix ADH_zinc_N PF00107.26 OWF49126.1 - 7.2e-12 45.4 0.4 4.9e-11 42.7 0.2 2.2 2 1 1 3 3 3 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OWF49126.1 - 0.00037 20.1 0.2 0.0033 17.0 0.2 2.2 1 1 1 2 2 2 1 Glucose dehydrogenase C-terminus Cu-oxidase_3 PF07732.15 OWF49127.1 - 8.9e-40 135.4 5.0 2.6e-36 124.2 1.3 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF49127.1 - 1.2e-34 119.0 11.1 4.3e-30 104.2 0.9 3.4 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF49127.1 - 2e-20 73.5 2.7 8.8e-19 68.2 1.8 2.7 2 1 0 2 2 2 1 Multicopper oxidase DUF295 PF03478.18 OWF49127.1 - 0.037 13.6 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF295) HtrL_YibB PF09612.10 OWF49128.1 - 2.8e-16 59.9 2.1 4e-16 59.3 2.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Ank_2 PF12796.7 OWF49129.1 - 1.2e-07 32.3 0.0 0.0012 19.3 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF49129.1 - 4.8e-06 27.0 0.2 0.046 14.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) MLTD_N PF06474.12 OWF49130.1 - 2.4e-08 34.0 22.5 13 6.1 0.7 9.3 1 1 11 12 12 12 12 MltD lipid attachment motif DUF3272 PF11676.8 OWF49130.1 - 0.14 12.4 27.6 14 6.0 0.3 6.7 1 1 6 7 7 7 0 Protein of unknown function (DUF3272) DUF5409 PF17421.2 OWF49130.1 - 0.89 10.3 27.9 4 8.2 0.1 5.1 1 1 1 2 2 2 0 Family of unknown function (DUF5409) MLTD_N PF06474.12 OWF49131.1 - 6e-07 29.5 14.2 8.3 6.7 0.6 7.0 1 1 8 9 9 9 9 MltD lipid attachment motif DUF5409 PF17421.2 OWF49131.1 - 0.25 12.1 17.1 3.1 8.6 0.1 3.8 1 1 1 2 2 2 0 Family of unknown function (DUF5409) DUF3272 PF11676.8 OWF49131.1 - 0.38 11.0 16.8 32 4.9 0.5 4.8 1 1 5 6 6 6 0 Protein of unknown function (DUF3272) HMG_box PF00505.19 OWF49133.1 - 8.5e-26 90.2 0.6 4.9e-25 87.7 0.9 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF49133.1 - 1.6e-09 38.2 0.4 3.3e-09 37.2 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.25 OWF49134.1 - 1.7e-68 230.9 0.0 2.9e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49134.1 - 2.3e-38 131.9 0.0 4.5e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF49134.1 - 4.9e-08 32.6 0.0 1.5e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OWF49134.1 - 7.9e-05 22.1 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OWF49134.1 - 0.0088 15.7 0.7 0.075 12.6 0.0 2.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 OWF49134.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF49134.1 - 7.2 5.3 10.0 0.57 8.9 0.0 2.9 4 0 0 4 4 4 0 Fungal protein kinase XK-related PF09815.9 OWF49135.1 - 3e-93 312.6 20.5 3.6e-93 312.3 20.5 1.0 1 0 0 1 1 1 1 XK-related protein SGL PF08450.12 OWF49136.1 - 1.6e-80 270.3 0.9 1.9e-80 270.0 0.9 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_2 PF13360.6 OWF49136.1 - 0.0039 16.8 0.0 0.57 9.7 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Reg_prop PF07494.11 OWF49136.1 - 0.0048 17.0 0.8 0.4 11.0 0.1 3.1 2 0 0 2 2 2 1 Two component regulator propeller Arylesterase PF01731.20 OWF49136.1 - 0.09 13.0 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Arylesterase SGL PF08450.12 OWF49137.1 - 4.6e-78 262.2 0.3 5.3e-78 262.0 0.3 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF49137.1 - 0.0035 17.4 0.9 1.2 9.6 0.1 2.9 2 0 0 2 2 2 2 Two component regulator propeller DUF839 PF05787.13 OWF49137.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) SGL PF08450.12 OWF49138.1 - 4.2e-47 160.8 0.1 4.6e-47 160.7 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Cytotoxic PF09000.10 OWF49138.1 - 0.033 14.5 0.2 6.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Cytotoxic SGL PF08450.12 OWF49139.1 - 5e-21 75.4 0.1 5.7e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region SGL PF08450.12 OWF49140.1 - 1.7e-78 263.7 0.4 1.9e-78 263.5 0.4 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF49140.1 - 0.0018 18.2 0.1 4 8.0 0.0 2.7 2 0 0 2 2 2 2 Two component regulator propeller NHL PF01436.21 OWF49140.1 - 0.032 14.3 0.1 0.22 11.6 0.0 2.5 3 0 0 3 3 3 0 NHL repeat WD40 PF00400.32 OWF49141.1 - 1.9e-14 53.8 14.6 0.00066 20.4 0.1 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 OWF49141.1 - 0.00068 18.4 1.8 0.54 8.8 0.1 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 OWF49141.1 - 0.0019 18.1 1.1 1.1 9.1 0.1 2.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Thyroglobulin_1 PF00086.18 OWF49141.1 - 0.072 12.8 1.0 14 5.4 0.2 2.8 3 0 0 3 3 3 0 Thyroglobulin type-1 repeat Exonuc_X-T_C PF08411.10 OWF49141.1 - 0.083 12.0 0.0 1.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Exonuclease C-terminal G-gamma PF00631.22 OWF49142.1 - 2.3e-11 43.5 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain LRR_8 PF13855.6 OWF49143.1 - 4.1e-30 103.3 48.0 1.6e-12 46.9 12.6 7.7 7 1 0 8 8 8 6 Leucine rich repeat TIR_2 PF13676.6 OWF49143.1 - 4.7e-13 49.8 0.3 1.1e-12 48.6 0.1 1.7 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 OWF49143.1 - 1.3e-12 47.7 54.9 0.0005 20.4 4.8 11.2 7 2 3 11 11 11 5 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF49143.1 - 4e-11 43.0 0.2 7.3e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 OWF49143.1 - 4.5e-06 26.6 4.1 2.9e-05 24.0 0.2 3.4 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF49143.1 - 9e-06 25.6 36.8 1.5 9.7 0.4 12.5 12 1 0 12 12 12 2 Leucine Rich Repeat LRR_9 PF14580.6 OWF49143.1 - 0.00014 21.4 10.1 0.00017 21.1 1.6 2.9 3 0 0 3 3 3 2 Leucine-rich repeat DUF1385 PF07136.11 OWF49143.1 - 0.05 12.9 0.3 0.12 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) LRR_6 PF13516.6 OWF49143.1 - 0.13 12.4 40.8 8.1 6.8 0.9 11.5 12 0 0 12 12 12 0 Leucine Rich repeat Glyco_transf_10 PF00852.19 OWF49144.1 - 3.5e-31 108.3 0.0 4.5e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term MFS_1 PF07690.16 OWF49145.1 - 2.1e-54 184.8 27.0 2.7e-54 184.4 27.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF49145.1 - 1.9e-10 40.2 15.6 2.7e-10 39.7 6.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Ni_hydr_CYTB PF01292.20 OWF49145.1 - 0.65 9.6 11.5 0.79 9.3 9.5 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4010 PF13194.6 OWF49145.1 - 2 8.1 11.8 0.02 14.6 2.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) Glyco_transf_10 PF00852.19 OWF49146.1 - 2e-45 154.7 1.3 3.7e-45 153.8 1.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF49146.1 - 1.8e-16 60.6 1.8 4.6e-16 59.2 0.4 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 OWF49147.1 - 4.2e-43 147.1 3.0 4.2e-43 147.1 3.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF49147.1 - 9.7e-18 64.6 2.0 1.2e-16 61.2 0.7 2.6 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 OWF49148.1 - 1.1e-50 171.8 3.3 1.7e-50 171.2 3.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF49148.1 - 1.2e-16 61.1 0.3 3.2e-16 59.7 0.3 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF1461 PF07314.11 OWF49148.1 - 0.086 12.7 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF347 PF03988.12 OWF49149.1 - 0.0091 16.2 1.1 0.029 14.6 0.3 2.2 3 0 0 3 3 3 1 Repeat of Unknown Function (DUF347) TMEM154 PF15102.6 OWF49149.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 OWF49149.1 - 0.062 12.1 0.3 0.2 10.5 0.1 1.7 2 0 0 2 2 2 0 Amnionless Ninjurin PF04923.12 OWF49149.1 - 0.065 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Ninjurin DUF3377 PF11857.8 OWF49149.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 OWF49149.1 - 0.14 13.1 0.0 0.23 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5367 PF17329.2 OWF49149.1 - 0.15 12.2 0.3 0.24 11.5 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5367) LRR19-TM PF15176.6 OWF49149.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Podoplanin PF05808.11 OWF49149.1 - 0.22 11.6 1.2 0.27 11.3 0.6 1.5 1 1 0 1 1 1 0 Podoplanin MAM PF00629.23 OWF49150.1 - 4.4e-34 117.7 0.0 8.7e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Astacin PF01400.24 OWF49150.1 - 3e-24 85.7 0.0 5e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) HLH PF00010.26 OWF49151.1 - 6.9e-17 61.2 2.7 1.2e-16 60.4 2.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF49151.1 - 1e-12 48.0 0.2 2.2e-12 47.0 0.2 1.5 1 0 0 1 1 1 1 Hairy Orange dCache_2 PF08269.11 OWF49151.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cache domain MRP-S35 PF10246.9 OWF49152.1 - 3.9e-36 123.2 0.0 5.7e-36 122.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 HD_3 PF13023.6 OWF49153.1 - 4.7e-49 166.5 0.4 5.4e-49 166.3 0.4 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OWF49153.1 - 8.5e-14 51.7 0.1 1.2e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OWF49153.1 - 7.2e-05 23.0 0.0 0.00019 21.6 0.0 1.7 1 1 0 1 1 1 1 HD domain LcrG PF07216.12 OWF49153.1 - 0.062 13.2 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 LcrG protein Cytochrom_B562 PF07361.11 OWF49153.1 - 1.4 9.7 4.5 3.3 8.4 0.1 2.6 2 1 1 3 3 3 0 Cytochrome b562 IBR PF01485.21 OWF49154.1 - 4.2e-14 52.5 20.8 6.9e-09 35.8 6.5 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Peptidase_S9_N PF02897.15 OWF49155.1 - 6.2e-143 476.5 0.1 8.5e-143 476.1 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OWF49155.1 - 5.7e-68 228.6 0.0 9.2e-68 227.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2345 PF10106.9 OWF49156.1 - 8e-11 42.0 35.5 0.00072 19.4 13.2 4.7 1 1 3 4 4 4 4 Uncharacterized protein conserved in bacteria (DUF2345) MNSV_P7B PF06692.11 OWF49156.1 - 0.00098 19.1 28.8 2.9 7.9 0.3 7.7 1 1 6 7 7 7 4 Melon necrotic spot virus P7B protein DUF2345 PF10106.9 OWF49157.1 - 0.027 14.4 0.5 0.035 14.0 0.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) MNSV_P7B PF06692.11 OWF49157.1 - 0.051 13.6 1.7 0.49 10.4 0.2 2.1 1 1 1 2 2 2 0 Melon necrotic spot virus P7B protein DUF1654 PF07867.11 OWF49157.1 - 0.13 12.0 0.5 9.2 6.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1654) MFA1_2 PF17317.2 OWF49157.1 - 2.9 7.7 6.7 10 6.0 0.5 2.9 2 2 1 3 3 3 0 Mating hormone A-factor 1&2 DUF4573 PF15140.6 OWF49158.1 - 3.2e-16 59.6 21.0 2.2e-08 34.1 3.5 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) DUF684 PF05075.14 OWF49158.1 - 7.6e-11 41.6 17.4 0.74 8.7 0.1 7.2 1 1 9 10 10 10 10 Protein of unknown function (DUF684) TEX13 PF15186.6 OWF49158.1 - 0.001 18.8 30.6 3 7.5 1.8 6.6 1 1 5 6 6 6 6 Testis-expressed sequence 13 protein family MEIOC PF15189.6 OWF49158.1 - 0.002 17.7 10.1 10 5.7 0.1 5.5 1 1 5 6 6 6 3 Meiosis-specific coiled-coil domain-containing protein MEIOC FLYWCH_N PF15423.6 OWF49158.1 - 0.0027 17.8 38.7 9.3 6.4 1.1 9.2 1 1 10 11 11 11 6 FLYWCH-type zinc finger-containing protein TPR_12 PF13424.6 OWF49158.1 - 0.097 13.0 8.3 1.1 9.6 0.0 5.0 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_5 PF12688.7 OWF49158.1 - 1 9.6 27.5 3.5 7.9 0.6 6.3 1 1 6 7 7 7 0 Tetratrico peptide repeat Kelch_1 PF01344.25 OWF49159.1 - 4.2e-17 61.5 5.5 0.00024 20.6 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OWF49159.1 - 8.1e-17 60.8 2.9 0.00091 19.2 0.1 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 OWF49159.1 - 4.9e-14 52.1 13.7 0.0015 18.5 0.2 6.0 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF49159.1 - 1.3e-12 47.2 9.1 0.0016 18.4 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OWF49159.1 - 6.9e-12 45.3 4.5 0.037 14.3 0.0 6.6 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF49159.1 - 1.8e-11 43.9 4.2 0.021 15.1 0.0 5.3 6 0 0 6 6 6 3 Kelch motif RAG2 PF03089.14 OWF49159.1 - 0.19 10.7 0.0 0.79 8.6 0.0 2.0 2 0 0 2 2 2 0 Recombination activating protein 2 zf-C2H2_4 PF13894.6 OWF49160.1 - 0.0007 20.2 44.9 0.12 13.3 1.6 6.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF49160.1 - 0.23 11.9 19.0 0.24 11.9 1.1 4.2 5 0 0 5 5 5 0 Zinc-finger double domain Mut7-C PF01927.16 OWF49160.1 - 0.4 10.8 10.7 2.6 8.1 0.2 3.5 3 0 0 3 3 3 0 Mut7-C RNAse domain zf-C2H2 PF00096.26 OWF49160.1 - 2.3 8.8 43.8 0.13 12.7 1.1 6.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type Myotub-related PF06602.14 OWF49161.1 - 1.4e-135 451.8 1.2 1.4e-135 451.8 1.2 1.3 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain GRAM PF02893.20 OWF49161.1 - 0.0023 17.8 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 GRAM domain HMMR_C PF15908.5 OWF49161.1 - 0.034 14.4 0.6 0.074 13.3 0.6 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal KELK PF15796.5 OWF49161.1 - 0.079 13.4 3.0 0.17 12.3 3.0 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TSP_1 PF00090.19 OWF49162.1 - 6.3e-26 90.3 25.4 3.5e-13 49.6 10.0 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF49162.1 - 1.2e-13 51.4 0.9 3.1e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 OWF49162.1 - 2.8e-09 37.2 1.0 4.9e-09 36.4 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF49162.1 - 3.7e-09 36.5 0.0 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain CarboxypepD_reg PF13620.6 OWF49162.1 - 1.4e-05 25.3 0.0 8.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain ig PF00047.25 OWF49162.1 - 0.00016 21.8 0.4 0.0005 20.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 OWF49162.1 - 0.00082 19.5 2.4 0.044 13.9 0.0 3.6 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF49162.1 - 0.022 15.0 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Peptidase_S8 PF00082.22 OWF49164.1 - 1.5e-32 113.1 4.6 2e-32 112.7 4.6 1.2 1 0 0 1 1 1 1 Subtilase family DUF382 PF04037.13 OWF49165.1 - 0.12 12.6 0.1 6.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF382) FoP_duplication PF13865.6 OWF49165.1 - 0.22 12.1 3.1 0.4 11.3 3.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Tristanin_u2 PF16638.5 OWF49165.1 - 2.2 9.1 4.7 5.2 7.9 4.7 1.7 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers BK_channel_a PF03493.18 OWF49166.1 - 1.6e-10 41.0 0.7 5.7e-10 39.3 0.1 2.2 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit ADAM_CR_2 PF17771.1 OWF49167.1 - 3.3e-11 43.5 5.9 3.3e-11 43.5 5.9 3.0 2 1 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 OWF49167.1 - 4.3e-08 33.3 0.1 1.2e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease FAP PF07174.11 OWF49167.1 - 4.4 6.7 15.9 6.5 6.1 15.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Cpn60_TCP1 PF00118.24 OWF49168.1 - 1.5e-157 525.2 14.6 1.7e-157 525.0 14.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 OWF49168.1 - 0.039 13.4 0.0 0.09 12.3 0.0 1.7 1 0 0 1 1 1 0 Telomere recombination ECH_1 PF00378.20 OWF49169.1 - 5.8e-42 143.7 0.0 8.2e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF49169.1 - 2.8e-19 69.8 0.0 3.8e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OWF49169.1 - 0.016 15.1 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S49 Glyco_hydro_64 PF16483.5 OWF49169.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 Beta-1,3-glucanase Suc_Fer-like PF06999.12 OWF49170.1 - 0.02 14.7 0.2 0.037 13.9 0.2 1.3 1 1 0 1 1 1 0 Sucrase/ferredoxin-like Presenilin PF01080.17 OWF49170.1 - 0.48 9.1 2.9 0.83 8.4 2.9 1.3 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OWF49171.1 - 7.4e-48 163.2 0.1 9.5e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49171.1 - 6.2e-21 74.8 0.2 4.8e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Gemin7 PF11095.8 OWF49172.1 - 3.1e-25 87.8 0.1 3.6e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) DUF3808 PF10300.9 OWF49173.1 - 1.2e-111 373.8 8.1 1.8e-111 373.3 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.6 OWF49173.1 - 1.2e-06 28.3 6.3 0.28 11.5 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF49173.1 - 3e-05 23.6 5.8 1.1 9.1 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF49173.1 - 8.9e-05 22.7 8.4 1.1 9.7 0.1 4.7 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF49173.1 - 0.00018 21.9 8.9 37 5.2 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF49173.1 - 0.00031 21.3 0.7 7.9 7.6 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF49173.1 - 0.00061 19.7 11.9 6.7 7.1 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat Pox_H7 PF04787.12 OWF49173.1 - 0.023 15.2 1.0 0.023 15.2 1.0 2.0 2 0 0 2 2 2 0 Late protein H7 TPR_11 PF13414.6 OWF49173.1 - 0.025 14.3 0.1 5.4 6.8 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 OWF49173.1 - 0.028 14.9 8.4 31 5.2 0.0 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat DUF1266 PF06889.11 OWF49173.1 - 0.063 13.3 0.4 0.17 11.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) ANAPC5 PF12862.7 OWF49173.1 - 0.11 12.5 2.3 0.49 10.5 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 OWF49173.1 - 0.61 10.2 2.5 33 4.8 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat BST2 PF16716.5 OWF49173.1 - 3.4 8.3 7.2 0.83 10.3 2.0 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 EF-hand_1 PF00036.32 OWF49174.1 - 2.5e-28 95.5 9.0 4.2e-08 32.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF49174.1 - 1e-26 93.2 5.4 5.3e-13 49.2 1.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF49174.1 - 1.1e-23 81.6 7.4 1.7e-09 36.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF49174.1 - 5.2e-23 79.0 4.4 1.9e-08 33.6 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF49174.1 - 2.1e-14 53.1 12.8 2e-07 30.8 0.6 4.1 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF49174.1 - 2.6e-06 27.7 1.4 0.0064 16.8 0.5 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OWF49174.1 - 3.3e-06 27.1 1.4 0.29 11.1 0.0 3.9 1 1 3 4 4 4 2 Caleosin related protein EF-hand_4 PF12763.7 OWF49174.1 - 2.3e-05 24.3 1.9 0.028 14.4 0.3 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand PMBR PF09373.10 OWF49174.1 - 0.0028 17.7 0.1 9.6 6.6 0.0 4.5 4 0 0 4 4 4 1 Pseudomurein-binding repeat DUF1707 PF08044.11 OWF49174.1 - 0.0079 16.2 0.4 11 6.2 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1707) IL5 PF02025.15 OWF49174.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 Interleukin 5 ClpS PF02617.17 OWF49174.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS EF-hand_9 PF14658.6 OWF49174.1 - 0.047 14.0 0.1 0.37 11.2 0.0 2.1 2 1 0 2 2 2 0 EF-hand domain Excalibur PF05901.11 OWF49174.1 - 0.1 13.2 1.3 11 6.7 0.0 2.7 2 0 0 2 2 2 0 Excalibur calcium-binding domain COQ7 PF03232.13 OWF49174.1 - 0.11 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 SOGA PF11365.8 OWF49174.1 - 0.14 13.3 1.7 0.16 13.1 0.3 1.8 2 0 0 2 2 2 0 Protein SOGA zf-C2HC_2 PF13913.6 OWF49175.1 - 3.4 7.7 5.2 2.7 8.0 0.5 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Cript PF10235.9 OWF49175.1 - 5.5 7.6 9.1 0.32 11.6 2.9 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT F5_F8_type_C PF00754.25 OWF49176.1 - 8.2e-15 55.0 0.0 9.1e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain 7tm_1 PF00001.21 OWF49177.1 - 5.1e-29 101.4 6.7 6.6e-29 101.0 6.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF49177.1 - 1.1e-05 25.3 8.8 0.00013 21.8 7.0 2.2 2 0 0 2 2 2 1 Olfactory receptor TMCO5 PF14992.6 OWF49177.1 - 0.012 15.2 1.2 0.017 14.7 0.6 1.5 1 1 0 1 1 1 0 TMCO5 family Ninjurin PF04923.12 OWF49177.1 - 9.2 6.3 10.4 55 3.8 0.1 3.7 2 1 0 2 2 2 0 Ninjurin DTC PF18102.1 OWF49178.1 - 1.4e-57 193.6 0.2 3.4e-57 192.3 0.0 1.8 2 0 0 2 2 2 1 Deltex C-terminal domain zf-RING_2 PF13639.6 OWF49178.1 - 5.4e-08 33.0 10.9 1.4e-07 31.8 9.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF49178.1 - 1.1e-06 28.4 11.2 2.6e-06 27.1 11.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF49178.1 - 2.5e-06 27.2 11.7 6.8e-06 25.9 11.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF49178.1 - 3.3e-06 26.9 8.8 3.3e-06 26.9 8.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF49178.1 - 2.9e-05 23.8 8.2 2.9e-05 23.8 8.2 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF49178.1 - 5e-05 23.2 10.5 0.00014 21.7 10.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Macro PF01661.21 OWF49178.1 - 0.00011 22.2 0.0 0.00031 20.7 0.0 1.7 1 0 0 1 1 1 1 Macro domain zf-RING_UBOX PF13445.6 OWF49178.1 - 0.00023 21.1 4.1 0.00023 21.1 4.1 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 OWF49178.1 - 0.00035 20.8 6.7 0.00087 19.5 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF49178.1 - 0.005 17.0 11.4 0.021 15.0 9.2 2.6 2 1 1 3 3 3 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OWF49178.1 - 0.014 15.2 6.3 0.042 13.6 6.3 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 OWF49178.1 - 0.038 13.9 0.9 0.088 12.8 0.9 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 OWF49178.1 - 0.062 13.4 4.0 0.21 11.7 4.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OWF49178.1 - 0.11 12.4 2.6 0.33 10.9 2.6 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 OWF49178.1 - 0.73 10.0 5.6 0.99 9.6 2.6 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-P11 PF03854.14 OWF49178.1 - 0.88 9.3 6.1 3 7.6 6.1 1.9 1 0 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.8 OWF49178.1 - 1 9.2 5.5 2.5 8.0 5.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OWF49178.1 - 4.6 7.1 10.8 0.2 11.4 4.2 2.2 2 0 0 2 2 2 0 RING-like zinc finger Rubredoxin_2 PF18073.1 OWF49178.1 - 7.7 6.3 6.3 0.4 10.5 0.9 1.7 2 0 0 2 2 1 0 Rubredoxin metal binding domain Macro PF01661.21 OWF49179.1 - 9.1e-38 128.9 0.1 9.4e-22 77.3 0.0 2.6 2 0 0 2 2 2 2 Macro domain RRM_1 PF00076.22 OWF49179.1 - 2.8e-06 27.1 3.7 0.029 14.2 0.0 4.8 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF49179.1 - 1.1e-05 25.2 0.2 0.35 10.8 0.1 4.1 3 0 0 3 3 3 3 Occluded RNA-recognition motif NID PF07292.13 OWF49179.1 - 2.2e-05 25.0 10.8 0.29 11.8 0.0 6.7 7 1 0 7 7 7 3 Nmi/IFP 35 domain (NID) Glycoprotein_B PF00606.18 OWF49179.1 - 0.026 14.0 0.2 0.064 12.7 0.2 1.6 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain Macro PF01661.21 OWF49180.1 - 5.9e-08 32.8 0.2 2.1e-07 31.0 0.1 2.0 2 1 0 2 2 2 1 Macro domain ACOX PF01756.19 OWF49181.1 - 1.1e-41 142.4 0.6 2.5e-41 141.2 0.6 1.5 1 1 0 1 1 1 1 Acyl-CoA oxidase Neur_chan_LBD PF02931.23 OWF49182.1 - 2.3e-44 151.5 0.0 4e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF49182.1 - 1.4e-14 54.8 11.1 2.5e-14 53.9 10.7 1.6 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.9 OWF49182.1 - 6.3 5.0 8.6 9.2 4.4 8.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Elicitin PF00964.17 OWF49184.1 - 0.00062 19.8 29.6 7.7 6.7 0.6 9.8 1 1 8 9 9 9 2 Elicitin Autophagy_act_C PF03987.15 OWF49184.1 - 0.0049 17.4 47.5 4.4e+02 1.6 0.0 19.4 23 1 1 24 24 24 0 Autophagocytosis associated protein, active-site domain RGS_DHEX PF18148.1 OWF49184.1 - 0.025 14.7 48.7 7.3 6.8 0.6 10.8 2 1 12 14 14 14 0 Regulator of G-protein signalling DHEX domain HMG_box PF00505.19 OWF49185.1 - 1.1e-11 44.9 35.3 1.2e-07 32.1 4.8 5.6 4 2 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF49185.1 - 0.0035 17.9 15.1 0.007 16.9 5.1 4.9 4 2 0 4 4 4 2 HMG-box domain Myb_DNA-binding PF00249.31 OWF49185.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Piwi PF02171.17 OWF49186.1 - 1.7e-114 382.2 0.0 2.4e-114 381.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 OWF49186.1 - 2.8e-34 117.2 0.0 8.6e-34 115.7 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 OWF49186.1 - 1.9e-32 112.7 0.0 7.3e-32 110.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 OWF49186.1 - 2.9e-25 88.7 0.4 5.5e-25 87.8 0.4 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 OWF49186.1 - 1.6e-23 82.1 0.0 3.2e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OWF49186.1 - 3.3e-17 62.5 0.1 7.5e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain RIO1 PF01163.22 OWF49187.1 - 3.7e-63 212.6 1.2 7.4e-63 211.6 1.2 1.5 1 0 0 1 1 1 1 RIO1 family PHA_gran_rgn PF09650.10 OWF49187.1 - 0.064 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Reeler PF02014.16 OWF49188.1 - 3e-27 95.9 0.2 3e-27 95.9 0.2 1.5 2 0 0 2 2 2 1 Reeler domain Ribosomal_L19 PF01245.20 OWF49188.1 - 0.074 13.0 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L19 Reeler PF02014.16 OWF49189.1 - 1.8e-26 93.4 0.4 3.1e-26 92.6 0.1 1.5 2 0 0 2 2 2 1 Reeler domain PHO4 PF01384.20 OWF49190.1 - 1e-130 435.7 15.9 1.3e-130 435.4 15.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family She9_MDM33 PF05546.11 OWF49190.1 - 0.0059 16.4 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PHO4 PF01384.20 OWF49191.1 - 3.2e-131 437.4 14.9 4.3e-131 437.0 14.9 1.2 1 0 0 1 1 1 1 Phosphate transporter family She9_MDM33 PF05546.11 OWF49191.1 - 0.0082 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family SAP PF02037.27 OWF49192.1 - 0.0073 16.0 1.2 0.012 15.3 1.2 1.4 1 0 0 1 1 1 1 SAP domain C1q PF00386.21 OWF49193.1 - 0.00031 21.0 0.0 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 C1q domain Cnn_1N PF07989.11 OWF49193.1 - 0.0023 18.1 2.5 0.0023 18.1 2.5 2.1 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 PI_PP_I PF18363.1 OWF49193.1 - 0.015 15.5 0.5 0.033 14.4 0.5 1.6 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain YabA PF06156.13 OWF49193.1 - 0.33 11.6 10.2 1.3 9.7 3.4 2.4 1 1 1 2 2 2 0 Initiation control protein YabA KASH_CCD PF14662.6 OWF49193.1 - 0.43 10.4 12.0 16 5.2 12.0 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 OWF49193.1 - 0.46 9.8 6.5 0.75 9.1 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 OWF49193.1 - 0.87 9.8 9.5 5.6 7.2 9.6 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 OWF49193.1 - 1 9.9 6.9 2.7 8.5 6.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 OWF49193.1 - 1.2 8.4 4.9 1.8 7.8 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 OWF49193.1 - 1.7 9.1 13.6 2.7e+02 2.1 13.6 2.3 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 OWF49193.1 - 1.9 8.6 12.7 0.44 10.7 1.2 3.2 2 1 1 3 3 3 0 Basic region leucine zipper DivIC PF04977.15 OWF49193.1 - 2.9 7.7 8.3 0.65 9.8 3.2 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF3967 PF13152.6 OWF49193.1 - 3.5 7.5 4.8 0.63 9.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) bZIP_1 PF00170.21 OWF49193.1 - 4.4 7.5 9.6 2.3 8.4 0.8 2.9 1 1 3 4 4 4 0 bZIP transcription factor zf-C4H2 PF10146.9 OWF49193.1 - 5 7.4 10.8 6.8 6.9 10.8 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein NRBF2 PF08961.10 OWF49193.1 - 5.9 6.5 10.4 38 3.8 0.5 3.0 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Mod_r PF07200.13 OWF49193.1 - 6.3 6.9 10.4 25 5.0 8.9 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ank_2 PF12796.7 OWF49194.1 - 5.5e-11 42.9 1.5 8.9e-05 23.0 0.6 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF49194.1 - 8.9e-10 38.9 0.1 0.028 15.0 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 OWF49194.1 - 1.4e-08 34.3 24.8 1.4e-07 31.0 20.2 2.3 1 1 1 2 2 2 2 Ion transport protein Ank_5 PF13857.6 OWF49194.1 - 8.3e-08 32.4 0.1 0.1 12.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF49194.1 - 2e-06 27.7 0.0 3.2 8.6 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 OWF49194.1 - 0.0016 18.8 0.2 23 5.7 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat SUR7 PF06687.12 OWF49194.1 - 0.27 10.8 7.2 0.071 12.7 0.3 2.3 2 0 0 2 2 2 0 SUR7/PalI family GWT1 PF06423.12 OWF49194.1 - 0.46 10.6 4.7 0.26 11.4 1.2 2.4 2 0 0 2 2 2 0 GWT1 Renin_r PF07850.14 OWF49195.1 - 4.2e-35 120.3 0.1 9.7e-35 119.1 0.1 1.6 1 0 0 1 1 1 1 Renin receptor-like protein RabGAP-TBC PF00566.18 OWF49196.1 - 6e-54 183.0 0.7 7.6e-54 182.6 0.7 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Potex_coat PF06184.11 OWF49196.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein MSV199 PF10553.9 OWF49196.1 - 0.12 12.6 0.0 3.7 7.8 0.0 2.2 2 0 0 2 2 2 0 MSV199 domain DUF241 PF03087.14 OWF49197.1 - 0.028 14.2 2.9 0.096 12.5 2.5 1.9 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DASH_Duo1 PF08651.10 OWF49197.1 - 0.029 14.2 3.3 0.068 12.9 0.4 2.6 2 1 1 3 3 3 0 DASH complex subunit Duo1 LXG PF04740.12 OWF49197.1 - 0.042 13.6 1.8 0.077 12.7 1.8 1.6 1 1 0 1 1 1 0 LXG domain of WXG superfamily Ion_trans PF00520.31 OWF49197.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Ion transport protein DUF16 PF01519.16 OWF49197.1 - 0.11 12.9 2.5 0.16 12.5 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 KxDL PF10241.9 OWF49197.1 - 0.22 11.8 6.7 0.33 11.2 3.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein DHR10 PF18595.1 OWF49197.1 - 2.5 8.2 8.2 0.96 9.5 5.5 1.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Ion_trans PF00520.31 OWF49198.1 - 3e-14 52.8 22.2 4.7e-14 52.2 22.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 OWF49198.1 - 1.5e-09 38.3 0.0 0.00012 22.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF49198.1 - 0.00012 22.2 0.0 0.15 12.7 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OWF49198.1 - 0.00056 20.2 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF49198.1 - 0.00091 19.6 0.0 0.074 13.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OWF49198.1 - 0.013 16.1 0.0 0.1 13.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Post_transc_reg PF13797.6 OWF49198.1 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Post-transcriptional regulator DUF241 PF03087.14 OWF49198.1 - 0.37 10.6 2.3 0.82 9.5 1.3 2.1 2 1 0 2 2 2 0 Arabidopsis protein of unknown function Lipase_GDSL_2 PF13472.6 OWF49199.1 - 3.4e-05 24.3 0.0 3.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Neurexophilin PF06312.12 OWF49200.1 - 1.4e-06 27.9 0.4 3.2e-06 26.8 0.4 1.5 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF49200.1 - 0.0017 19.1 0.0 0.0037 18.0 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Invasin_D3 PF09134.10 OWF49200.1 - 0.067 13.5 0.3 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Invasin, domain 3 Cadherin_5 PF17892.1 OWF49200.1 - 0.076 13.0 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 Cadherin-like domain 2TM PF13239.6 OWF49200.1 - 0.13 12.5 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 2TM domain Tubulin PF00091.25 OWF49201.1 - 3.1e-67 226.6 0.0 4.9e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF49201.1 - 1.3e-36 125.5 0.0 2.1e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OWF49201.1 - 0.0009 19.5 0.1 0.0066 16.7 0.1 2.3 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OWF49201.1 - 0.0033 17.1 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OWF49201.1 - 0.029 13.6 0.0 0.077 12.2 0.0 1.7 1 0 0 1 1 1 0 Tubulin like Astacin PF01400.24 OWF49202.1 - 1.8e-60 203.9 1.2 3.4e-60 202.9 1.2 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 OWF49202.1 - 9.3e-29 100.4 0.2 1.8e-28 99.5 0.2 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu HNHc_6 PF16784.5 OWF49202.1 - 1.2 8.7 3.8 0.67 9.5 0.6 2.0 2 0 0 2 2 2 0 Putative HNHc nuclease TFIIF_beta_N PF17683.1 OWF49203.1 - 7.9e-23 81.6 0.3 3.5e-22 79.5 0.3 2.0 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TMEM208_SND2 PF05620.11 OWF49203.1 - 9.8 5.9 8.0 8.5 6.1 1.6 2.2 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Rep_fac_C PF08542.11 OWF49204.1 - 1.2e-18 67.2 0.2 2.5e-18 66.2 0.2 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OWF49204.1 - 7.8e-16 58.7 0.0 4.1e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OWF49204.1 - 2.9e-12 46.7 0.0 1.2e-09 38.2 0.0 2.5 1 1 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OWF49204.1 - 8.3e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 OWF49204.1 - 1.8e-05 25.0 0.3 7.4e-05 23.0 0.3 2.1 1 1 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 OWF49204.1 - 0.0003 21.2 0.0 0.0088 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 OWF49204.1 - 0.00042 20.2 0.0 0.0011 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF49204.1 - 0.00054 20.2 0.1 0.096 13.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OWF49204.1 - 0.00075 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OWF49204.1 - 0.0028 17.4 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OWF49204.1 - 0.0083 15.5 0.0 0.099 12.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OWF49204.1 - 0.016 15.6 0.0 0.27 11.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OWF49204.1 - 0.031 14.0 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 OWF49204.1 - 0.048 13.7 0.0 0.18 11.8 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OWF49204.1 - 0.087 12.8 0.0 0.61 10.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OWF49204.1 - 0.1 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OWF49204.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HMG_box PF00505.19 OWF49205.1 - 4.5e-28 97.5 3.7 7.4e-28 96.8 3.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF49205.1 - 3.6e-11 43.5 1.7 6.3e-11 42.7 1.7 1.3 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 OWF49205.1 - 5.8e-07 30.5 0.3 1.8e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 SOX transcription factor AAA PF00004.29 OWF49208.1 - 1e-55 187.8 0.0 1.6e-41 141.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OWF49208.1 - 5.6e-26 90.8 0.2 2.1e-25 88.9 0.2 2.1 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PEX-2N PF09263.10 OWF49208.1 - 1.8e-14 53.8 0.0 4.7e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OWF49208.1 - 2.1e-11 43.4 0.0 1.7e-08 34.1 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain NACHT PF05729.12 OWF49208.1 - 1.9e-09 37.7 0.7 1.4e-06 28.3 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 OWF49208.1 - 3.1e-09 37.4 1.8 0.0028 18.0 0.0 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OWF49208.1 - 1.1e-06 28.9 1.6 0.021 15.1 0.0 4.6 3 2 1 4 4 4 2 AAA domain AAA_14 PF13173.6 OWF49208.1 - 4.2e-06 26.8 0.0 0.0019 18.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 OWF49208.1 - 1.6e-05 25.2 0.0 0.18 12.2 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.14 OWF49208.1 - 6.9e-05 22.9 0.3 0.71 9.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OWF49208.1 - 0.00021 21.1 0.0 0.0026 17.5 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 OWF49208.1 - 0.00071 20.1 0.0 0.033 14.7 0.0 3.2 2 0 0 2 2 2 1 ABC transporter AAA_2 PF07724.14 OWF49208.1 - 0.00074 19.7 0.0 0.046 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 OWF49208.1 - 0.00095 18.8 0.3 2.6 7.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 OWF49208.1 - 0.0013 18.0 0.1 0.25 10.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 OWF49208.1 - 0.0017 17.6 0.0 0.043 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 OWF49208.1 - 0.0021 18.6 5.9 0.02 15.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 OWF49208.1 - 0.0021 18.2 0.0 3.7 7.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OWF49208.1 - 0.0029 17.0 0.3 1.4 8.2 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OWF49208.1 - 0.0036 17.0 0.0 0.79 9.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 OWF49208.1 - 0.004 17.7 0.3 6.7 7.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 OWF49208.1 - 0.0058 15.9 0.0 0.6 9.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 OWF49208.1 - 0.0063 16.2 0.1 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 OWF49208.1 - 0.008 16.3 0.0 1.3 9.2 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 OWF49208.1 - 0.0098 15.6 0.0 5 6.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 OWF49208.1 - 0.016 15.5 0.1 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OWF49208.1 - 0.049 13.6 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 OWF49208.1 - 0.068 13.1 0.0 1.3 8.9 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OWF49208.1 - 0.068 12.7 0.0 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 OWF49208.1 - 0.071 13.5 0.5 26 5.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 OWF49208.1 - 0.074 12.2 0.0 4.5 6.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 OWF49208.1 - 0.077 12.7 0.1 13 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 OWF49208.1 - 0.086 12.6 0.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 OWF49208.1 - 0.096 12.8 0.1 0.45 10.6 0.0 2.3 2 0 0 2 2 1 0 50S ribosome-binding GTPase ATPase PF06745.13 OWF49208.1 - 0.11 11.8 0.2 7.9 5.8 0.0 2.4 2 0 0 2 2 2 0 KaiC Apolipoprotein PF01442.18 OWF49208.1 - 1.3 8.9 4.3 0.45 10.4 0.3 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain WW PF00397.26 OWF49209.1 - 3.3e-13 49.4 14.9 1.8e-09 37.5 2.5 3.5 3 0 0 3 3 3 3 WW domain FAM181 PF15238.6 OWF49209.1 - 4.8e-08 33.2 1.5 4.8e-08 33.2 1.5 2.9 2 1 0 3 3 3 1 FAM181 POP1 PF06978.11 OWF49209.1 - 0.047 13.7 5.1 0.088 12.8 5.1 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 TMEM247 PF15444.6 OWF49209.1 - 0.067 13.2 3.7 0.15 12.1 3.7 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Roughex PF06020.11 OWF49209.1 - 0.23 10.6 7.5 0.47 9.5 7.5 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Glyco_transf_24 PF18404.1 OWF49210.1 - 1.7e-145 483.4 4.5 3.3e-145 482.5 4.5 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OWF49210.1 - 4.9e-70 236.4 2.7 2e-61 208.2 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_15 PF18403.1 OWF49210.1 - 4.3e-59 200.0 4.7 1.5e-49 168.8 0.5 3.8 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OWF49210.1 - 3.3e-52 177.1 0.1 6.7e-52 176.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OWF49210.1 - 9e-37 125.5 0.0 2.7e-36 124.0 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 OWF49210.1 - 1.5e-33 115.6 0.8 3.9e-33 114.2 0.2 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OWF49210.1 - 1.2e-06 28.3 0.5 4.7e-06 26.4 0.5 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF4218 PF13960.6 OWF49211.1 - 1.3e-11 44.1 0.0 3.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TatD_DNase PF01026.21 OWF49212.1 - 6.2e-11 42.2 0.0 7.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Pox_A32 PF04665.12 OWF49213.1 - 0.01 15.3 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Cyclin_N PF00134.23 OWF49214.1 - 1.1e-12 47.8 0.1 1.7e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OWF49214.1 - 6.6e-10 39.6 0.1 8.8e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin UCH PF00443.29 OWF49215.1 - 5.1e-14 52.4 1.8 5.1e-14 52.4 1.8 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF49215.1 - 8.3 5.9 12.3 19 4.7 12.3 1.8 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PDZ_6 PF17820.1 OWF49216.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Spc7 PF08317.11 OWF49216.1 - 0.031 13.2 0.2 0.043 12.7 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Bclt PF15318.6 OWF49216.1 - 0.044 13.6 0.4 0.089 12.6 0.4 1.4 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis Cnn_1N PF07989.11 OWF49216.1 - 0.068 13.3 0.5 0.11 12.6 0.5 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 MPS2 PF17060.5 OWF49216.1 - 0.15 11.3 0.4 0.23 10.7 0.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Hepatitis_core PF00906.20 OWF49216.1 - 3.5 7.1 6.9 8 5.9 6.9 1.6 1 0 0 1 1 1 0 Hepatitis core antigen RhoGEF PF00621.20 OWF49218.1 - 4.4e-39 134.6 1.1 7.5e-39 133.8 1.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 OWF49218.1 - 0.026 14.3 0.1 0.084 12.7 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain UPAR_LY6_2 PF16975.5 OWF49219.1 - 4.2e-06 26.9 15.5 7.2e-06 26.2 15.5 1.4 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Cdc6_C PF09079.11 OWF49220.1 - 3.4e-16 59.0 0.4 6.6e-16 58.1 0.4 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 OWF49220.1 - 1.7e-13 51.0 0.0 4.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OWF49220.1 - 5.7e-13 49.6 0.1 1.1e-10 42.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OWF49220.1 - 4e-12 46.7 0.0 8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OWF49220.1 - 8.4e-08 32.3 0.1 2e-07 31.1 0.0 1.7 2 0 0 2 2 1 1 NACHT domain AAA_lid_10 PF17872.1 OWF49220.1 - 1.6e-07 31.3 0.4 4.3e-07 30.0 0.4 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 OWF49220.1 - 2.2e-05 24.8 0.3 0.00022 21.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OWF49220.1 - 0.00041 20.1 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OWF49220.1 - 0.0012 18.8 0.0 0.011 15.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OWF49220.1 - 0.0013 18.5 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 OWF49220.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OWF49220.1 - 0.0034 17.2 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 OWF49220.1 - 0.0062 15.7 0.0 0.014 14.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 OWF49220.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OWF49220.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 OWF49220.1 - 0.017 15.1 0.1 0.7 9.8 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_7 PF12775.7 OWF49220.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OWF49220.1 - 0.019 14.9 0.0 0.47 10.3 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OWF49220.1 - 0.023 13.8 0.1 0.049 12.7 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 OWF49220.1 - 0.033 13.1 0.0 0.071 12.0 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD-helicase PF00580.21 OWF49220.1 - 0.039 13.5 0.9 0.058 12.9 0.0 1.7 2 0 0 2 2 1 0 UvrD/REP helicase N-terminal domain KAP_NTPase PF07693.14 OWF49220.1 - 0.046 13.0 0.1 7 5.8 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain cobW PF02492.19 OWF49220.1 - 0.049 13.2 0.1 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 OWF49220.1 - 0.058 13.6 0.3 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OWF49220.1 - 0.064 12.6 0.2 0.19 11.1 0.1 1.8 1 1 1 2 2 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.6 OWF49220.1 - 0.065 13.4 0.0 0.59 10.3 0.0 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain MA3 PF02847.17 OWF49221.1 - 9.8e-25 86.7 0.6 1.9e-24 85.8 0.6 1.5 1 0 0 1 1 1 1 MA3 domain Skp1 PF01466.19 OWF49221.1 - 0.19 11.9 3.0 0.76 9.9 3.0 2.1 1 0 0 1 1 1 0 Skp1 family, dimerisation domain PTB PF08416.13 OWF49222.1 - 4.5e-37 127.1 0.0 7e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 OWF49222.1 - 6.9e-10 38.9 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain PTEN_C2 PF10409.9 OWF49223.1 - 2.2e-31 108.4 0.6 7.7e-31 106.6 0.0 2.3 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OWF49223.1 - 0.91 9.3 4.2 0.77 9.6 1.0 2.6 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Exonuc_VII_L PF02601.15 OWF49223.1 - 9.2 5.7 20.9 3.5 7.1 10.5 2.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit HD PF01966.22 OWF49224.1 - 1.7e-12 47.6 0.5 5.1e-12 46.1 0.1 2.1 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 OWF49224.1 - 0.0018 18.1 1.0 0.0021 17.8 0.1 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Fz PF01392.22 OWF49225.1 - 2.1e-29 102.3 1.8 2.7e-29 102.0 1.8 1.1 1 0 0 1 1 1 1 Fz domain Innexin PF00876.18 OWF49226.1 - 1e-105 353.9 17.9 1.2e-105 353.7 17.9 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 OWF49227.1 - 1.8e-95 320.2 10.3 2.1e-95 320.0 10.3 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 OWF49229.1 - 8.1e-96 321.4 19.9 9.7e-96 321.1 19.9 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 OWF49230.1 - 6.1e-117 390.8 15.8 7e-117 390.6 15.8 1.0 1 0 0 1 1 1 1 Innexin GWT1 PF06423.12 OWF49230.1 - 0.13 12.3 2.3 3.1 7.9 0.2 2.8 2 1 0 2 2 2 0 GWT1 TatD_DNase PF01026.21 OWF49231.1 - 7.1e-10 38.7 0.0 9.3e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Methyltransf_21 PF05050.12 OWF49232.1 - 0.0013 18.8 0.1 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 OWF49232.1 - 0.005 16.4 0.5 0.0096 15.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FGAR-AT_linker PF18072.1 OWF49233.1 - 7.4e-07 29.6 45.1 2.3 8.9 0.9 13.0 1 1 13 14 14 14 5 Formylglycinamide ribonucleotide amidotransferase linker domain RepB-RCR_reg PF10723.9 OWF49233.1 - 8e-06 25.7 0.2 52 3.9 0.0 7.5 1 1 7 10 10 10 0 Replication regulatory protein RepB Abhydrolase_5 PF12695.7 OWF49233.1 - 0.053 13.3 0.2 72 3.1 0.0 4.4 1 1 3 5 5 5 0 Alpha/beta hydrolase family Glyco_hydro_56 PF01630.18 OWF49233.1 - 2.7 6.9 7.8 58 2.5 0.1 5.0 1 1 5 7 7 7 0 Hyaluronidase Galactosyl_T PF01762.21 OWF49234.1 - 7.7e-40 136.8 0.1 1.7e-39 135.6 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 OWF49234.1 - 0.009 15.5 0.4 0.02 14.3 0.4 1.7 1 1 0 1 1 1 1 Fringe-like Glycos_transf_2 PF00535.26 OWF49234.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Imm5 PF14423.6 OWF49234.1 - 0.13 12.5 0.2 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm5 zf-C3HC4_3 PF13920.6 OWF49236.1 - 5.6e-15 54.9 9.3 9.7e-15 54.2 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF49236.1 - 1.4e-07 31.3 10.5 2.5e-07 30.4 10.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF49236.1 - 1e-05 25.7 12.4 2.2e-05 24.7 12.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF49236.1 - 0.0066 16.4 10.2 0.011 15.6 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF49236.1 - 0.025 14.4 12.3 0.043 13.7 12.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF49236.1 - 0.16 11.7 5.1 0.14 11.9 1.6 2.8 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_UBOX PF13445.6 OWF49236.1 - 0.53 10.4 8.1 8.1 6.6 4.8 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 OWF49236.1 - 2.5 8.0 12.1 0.89 9.4 9.1 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Death PF00531.22 OWF49237.1 - 3.4e-05 23.9 0.0 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 Death domain Neur_chan_LBD PF02931.23 OWF49238.1 - 1.3e-35 122.9 0.0 2.6e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF49238.1 - 1.1e-14 55.1 2.3 1.5e-14 54.7 2.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.10 OWF49238.1 - 0.46 8.7 2.3 0.7 8.0 2.3 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ank_4 PF13637.6 OWF49240.1 - 2.7e-39 133.1 6.6 1e-13 51.4 0.0 5.0 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF49240.1 - 8.9e-38 127.9 12.8 2.9e-11 43.4 0.2 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF49240.1 - 1.4e-34 118.5 2.1 1.7e-12 47.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF49240.1 - 1.2e-32 108.3 1.5 7.7e-07 29.0 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 OWF49240.1 - 6.5e-30 102.2 3.5 9e-06 25.9 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Dynein_light PF01221.18 OWF49241.1 - 3e-28 97.9 0.6 3.6e-28 97.7 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.8 OWF49241.1 - 0.0046 16.8 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) Ground-like PF04155.18 OWF49241.1 - 0.039 14.6 0.1 0.055 14.1 0.1 1.2 1 0 0 1 1 1 0 Ground-like domain Swm2 PF17083.5 OWF49241.1 - 0.054 13.5 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Telomere_reg-2 PF10193.9 OWF49242.1 - 1.6e-28 99.3 2.4 3.3e-28 98.3 0.1 2.8 3 0 0 3 3 3 1 Telomere length regulation protein Ribonuclease_3 PF00636.26 OWF49242.1 - 0.16 12.6 0.1 0.6 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease III domain AAA PF00004.29 OWF49243.1 - 8.4e-39 133.0 0.0 2.4e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OWF49243.1 - 3.4e-05 23.6 0.0 6.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF49243.1 - 0.00011 22.3 0.1 0.00079 19.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF49243.1 - 0.0019 18.6 1.4 0.019 15.4 1.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OWF49243.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OWF49243.1 - 0.0048 17.2 2.5 0.08 13.2 1.1 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 OWF49243.1 - 0.043 13.0 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OWF49243.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OWF49243.1 - 0.1 12.2 0.6 7.1 6.2 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 OWF49243.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OWF49243.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain 7tm_7 PF08395.12 OWF49244.1 - 2.4e-18 66.5 22.9 3e-18 66.2 22.9 1.0 1 0 0 1 1 1 1 7tm Chemosensory receptor Trehalose_recp PF06151.13 OWF49244.1 - 9.2e-08 31.1 5.5 9.2e-08 31.1 5.5 2.0 2 0 0 2 2 2 2 Trehalose receptor Anoctamin PF04547.12 OWF49246.1 - 4.8e-15 55.3 9.8 1.7e-08 33.8 0.1 2.8 1 1 1 3 3 3 3 Calcium-activated chloride channel Thg1 PF04446.12 OWF49248.1 - 1.8e-50 170.1 0.6 2.8e-50 169.5 0.6 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OWF49248.1 - 6.7e-45 152.2 0.0 1.2e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain PH PF00169.29 OWF49249.1 - 2.9e-14 53.4 0.1 9.1e-14 51.8 0.1 1.9 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 OWF49249.1 - 9.8e-08 32.0 0.2 2.5e-07 30.7 0.2 1.8 1 0 0 1 1 1 1 SH2 domain PH_11 PF15413.6 OWF49249.1 - 0.022 15.2 0.1 0.58 10.6 0.1 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 OWF49249.1 - 0.062 13.7 0.4 0.77 10.1 0.0 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain DUF3740 PF12548.8 OWF49249.1 - 0.47 10.9 6.9 0.66 10.4 5.5 1.9 1 1 1 2 2 2 0 Sulfatase protein eIF3_subunit PF08597.10 OWF49249.1 - 4.3 7.2 18.5 9.8 6.0 18.5 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Fur_reg_FbpB PF13040.6 OWF49250.1 - 1e-06 28.2 6.3 99 2.6 0.0 12.4 14 0 0 14 14 14 0 Fur-regulated basic protein B Tudor-knot PF11717.8 OWF49250.1 - 0.00064 19.6 27.4 2.6e+02 1.6 0.1 11.6 2 1 2 4 4 4 0 RNA binding activity-knot of a chromodomain LRR_8 PF13855.6 OWF49251.1 - 1e-10 41.2 12.7 1.2e-09 37.8 2.5 3.8 1 1 3 4 4 4 4 Leucine rich repeat Ig_3 PF13927.6 OWF49251.1 - 8.2e-08 32.7 0.2 5.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF49251.1 - 3.4e-07 30.2 0.2 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF49251.1 - 1.2e-05 25.5 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRRCT PF01463.24 OWF49251.1 - 0.017 15.7 0.7 0.041 14.4 0.7 1.7 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain ig PF00047.25 OWF49251.1 - 0.069 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain LRR_4 PF12799.7 OWF49251.1 - 0.53 10.8 18.7 14 6.3 3.1 4.6 3 2 4 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF49251.1 - 3.7 8.5 11.2 27 5.8 0.0 5.8 6 1 0 6 6 6 0 Leucine Rich Repeat Drf_FH1 PF06346.12 OWF49252.1 - 2.7e-24 85.7 90.8 0.0015 18.2 8.6 8.1 1 1 4 6 6 6 6 Formin Homology Region 1 DUF1414 PF07208.11 OWF49253.1 - 0.042 13.8 1.9 1e+02 3.0 0.0 5.0 5 3 3 8 8 8 0 Protein of unknown function (DUF1414) Tail_P2_I PF09684.10 OWF49253.1 - 0.17 11.8 11.7 16 5.4 0.4 5.2 1 1 5 6 6 6 0 Phage tail protein (Tail_P2_I) DUF1413 PF07205.11 OWF49253.1 - 0.42 10.7 16.2 10 6.2 0.8 5.5 1 1 6 7 7 7 0 Domain of unknown function (DUF1413) Parvo_coat PF00740.18 OWF49253.1 - 0.65 8.6 3.8 1.2 7.7 0.4 2.0 1 1 1 2 2 2 0 Parvovirus coat protein VP2 TMEM237 PF15383.6 OWF49254.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 RRM_1 PF00076.22 OWF49255.1 - 1.4e-09 37.6 0.1 7.6e-08 32.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF49255.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA binding motif Nup188 PF10487.9 OWF49256.1 - 0.025 12.5 5.7 0.034 12.1 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 Methyltransf_14 PF08484.11 OWF49256.1 - 0.58 10.0 10.3 0.066 13.0 3.8 2.4 1 1 1 2 2 2 0 C-methyltransferase C-terminal domain SLED PF12140.8 OWF49256.1 - 6.7 7.3 6.2 1.6 9.2 1.1 2.4 1 1 1 2 2 2 0 SLED domain EXOSC1 PF10447.9 OWF49257.1 - 2.8e-18 66.5 0.7 2.1e-13 50.8 0.1 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 OWF49257.1 - 4.1e-10 39.3 1.1 4.2e-10 39.3 0.1 1.6 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region R2K_2 PF18299.1 OWF49257.1 - 0.0093 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 MOZ_SAS PF01853.18 OWF49258.1 - 2.9e-86 287.7 0.8 4.5e-86 287.1 0.8 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OWF49258.1 - 3.6e-23 80.9 2.4 1.1e-22 79.4 2.4 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain zf-C2HC PF01530.18 OWF49258.1 - 3.3e-13 49.5 4.5 7.7e-13 48.4 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 OWF49258.1 - 0.0024 18.2 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF305 PF03713.13 OWF49258.1 - 7 6.8 7.2 0.86 9.7 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF305) Adeno_E3_CR2 PF02439.15 OWF49259.1 - 0.045 13.5 2.1 0.045 13.5 2.1 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF3177 PF11375.8 OWF49259.1 - 0.082 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Mid2 PF04478.12 OWF49259.1 - 0.09 12.6 0.6 0.13 12.1 0.6 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DAG1 PF05454.11 OWF49259.1 - 0.12 11.8 0.7 0.13 11.6 0.0 1.4 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Cadherin_C_2 PF16492.5 OWF49259.1 - 0.2 12.4 0.0 0.2 12.4 0.0 2.3 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4690 PF15756.5 OWF49259.1 - 0.22 12.2 0.5 0.22 12.2 0.5 1.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 OWF49259.1 - 0.58 11.1 0.2 0.58 11.1 0.2 1.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PSS PF03034.15 OWF49260.1 - 2e-112 375.4 10.7 2e-112 375.4 10.7 1.6 2 0 0 2 2 2 1 Phosphatidyl serine synthase DUF998 PF06197.13 OWF49260.1 - 0.0088 15.7 0.1 0.0088 15.7 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF998) TctB PF07331.11 OWF49260.1 - 0.029 14.7 0.6 0.029 14.7 0.6 3.6 3 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF3382 PF11862.8 OWF49260.1 - 0.033 14.4 0.9 1.2 9.5 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) ABC2_membrane_3 PF12698.7 OWF49260.1 - 1.6 7.7 9.5 0.81 8.7 3.5 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2630 PF10944.8 OWF49261.1 - 0.13 12.8 0.1 9.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) PAM2 PF07145.15 OWF49262.1 - 5.9e-07 28.7 0.2 1.1e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Ataxin-2 C-terminal region LRR_8 PF13855.6 OWF49263.1 - 8.1e-41 137.6 38.8 5.6e-14 51.6 6.3 5.8 4 1 3 7 7 7 5 Leucine rich repeat 7tm_1 PF00001.21 OWF49263.1 - 1.8e-27 96.3 12.7 1.8e-27 96.3 12.7 1.9 3 0 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 OWF49263.1 - 4.4e-18 65.5 8.4 6.7e-12 45.5 0.1 3.0 2 1 0 3 3 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF49263.1 - 1.8e-14 53.6 25.8 0.0039 17.6 0.6 6.4 4 1 1 6 6 6 5 Leucine Rich repeats (2 copies) 7TM_GPCR_Srx PF10328.9 OWF49263.1 - 4.7e-12 46.1 15.2 1.1e-11 44.9 15.2 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Ldl_recept_a PF00057.18 OWF49263.1 - 4.9e-09 36.2 25.8 2.7e-05 24.3 3.8 3.6 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A LRR_6 PF13516.6 OWF49263.1 - 7.2e-09 35.0 6.5 0.94 9.7 0.0 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 OWF49263.1 - 4e-08 32.7 18.4 0.15 12.7 0.1 7.4 6 1 0 6 6 6 3 Leucine Rich Repeat 7TM_GPCR_Srsx PF10320.9 OWF49263.1 - 4e-06 26.4 14.4 4e-06 26.4 14.4 2.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_9 PF14580.6 OWF49263.1 - 8.5e-06 25.4 8.1 7.6e-05 22.3 3.4 2.8 1 1 1 2 2 2 1 Leucine-rich repeat 7TM_GPCR_Srv PF10323.9 OWF49263.1 - 0.00023 20.6 13.2 0.00044 19.7 13.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srbc PF10316.9 OWF49263.1 - 0.00054 19.5 11.4 0.00054 19.5 11.4 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Pkinase PF00069.25 OWF49263.1 - 0.00056 19.4 0.3 0.0039 16.6 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 OWF49263.1 - 0.0073 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Git3 PF11710.8 OWF49263.1 - 0.0079 16.0 6.4 0.022 14.5 6.4 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Pkinase_Tyr PF07714.17 OWF49263.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1647 PF07801.11 OWF49263.1 - 0.69 9.7 6.6 13 5.6 0.1 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1647) Ldl_recept_a PF00057.18 OWF49264.1 - 3.2e-15 56.1 28.3 6.4e-08 32.7 15.7 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 OWF49264.1 - 0.0072 17.1 1.2 0.016 15.9 0.1 2.0 1 1 1 2 2 2 1 Lectin C-type domain Porin_8 PF16966.5 OWF49264.1 - 0.054 12.5 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Porin-like glycoporin RafY Bac_rhamnosid_C PF17390.2 OWF49265.1 - 0.028 14.2 0.0 4.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_transf_7N PF13733.6 OWF49266.1 - 1.5e-52 176.8 0.0 2.9e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF49266.1 - 1.7e-28 98.0 0.0 9.7e-28 95.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF49266.1 - 0.019 14.4 0.0 0.052 13.0 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 CIDR1_gamma PF18562.1 OWF49266.1 - 0.5 10.5 2.1 1.1 9.5 2.1 1.6 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma Glyco_transf_7N PF13733.6 OWF49267.1 - 1.8e-51 173.3 0.1 1.8e-51 173.3 0.1 4.5 4 2 0 4 4 4 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF49267.1 - 4.3e-28 96.8 0.4 8.9e-28 95.8 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DAP10 PF07213.11 OWF49268.1 - 0.025 14.5 0.3 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 DAP10 membrane protein TMEM154 PF15102.6 OWF49268.1 - 0.046 13.6 2.4 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family TPPK_C PF12555.8 OWF49268.1 - 0.29 11.2 3.3 0.3 11.2 1.4 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Ribosomal_L26 PF16906.5 OWF49269.1 - 3.7e-40 136.3 7.7 5.2e-40 135.8 7.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OWF49269.1 - 2.1e-06 27.4 3.9 2.1e-06 27.4 3.9 2.0 2 0 0 2 2 2 1 KOW motif FlgT_C PF16538.5 OWF49269.1 - 0.029 14.9 0.2 0.048 14.2 0.2 1.3 1 0 0 1 1 1 0 Flagellar assembly protein T, C-terminal domain VEG PF06257.11 OWF49269.1 - 0.17 11.9 4.3 0.61 10.2 0.6 2.4 1 1 1 2 2 2 0 Biofilm formation stimulator VEG Macro PF01661.21 OWF49270.1 - 2.8e-52 175.7 1.7 3.9e-18 65.6 0.0 5.6 5 0 0 5 5 5 4 Macro domain SLS PF14611.6 OWF49270.1 - 0.00016 21.6 2.2 0.028 14.2 1.6 3.3 1 1 2 3 3 3 1 Mitochondrial inner-membrane-bound regulator DUF3106 PF11304.8 OWF49270.1 - 6.1 7.4 8.1 20 5.7 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Macro PF01661.21 OWF49271.1 - 2.7e-54 182.2 0.8 1.9e-18 66.6 0.0 4.7 4 0 0 4 4 4 4 Macro domain SLS PF14611.6 OWF49272.1 - 0.0011 18.8 5.9 0.0083 16.0 2.5 3.1 2 1 1 3 3 3 1 Mitochondrial inner-membrane-bound regulator Fasciclin PF02469.22 OWF49273.1 - 2e-70 235.0 2.4 3e-35 121.2 0.1 2.0 2 0 0 2 2 2 2 Fasciclin domain Chlamy_scaf PF09675.10 OWF49273.1 - 0.047 14.1 0.0 7 7.1 0.0 2.4 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) RseA_N PF03872.13 OWF49273.1 - 0.11 12.9 0.0 5.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain Fasciclin PF02469.22 OWF49274.1 - 3.9e-70 234.0 6.3 2.5e-35 121.5 0.2 2.0 2 0 0 2 2 2 2 Fasciclin domain Chlamy_scaf PF09675.10 OWF49274.1 - 0.0072 16.7 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 2 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) DUF211 PF02680.14 OWF49274.1 - 0.25 11.5 3.2 1.2 9.3 0.3 2.6 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 7tm_1 PF00001.21 OWF49275.1 - 5.3e-45 153.8 19.5 6.4e-45 153.5 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49275.1 - 4.2e-06 26.3 17.0 7.2e-05 22.3 17.0 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF49275.1 - 1.2e-05 24.8 17.0 0.00027 20.3 17.0 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF49275.1 - 5e-05 23.1 17.4 7e-05 22.6 17.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF49275.1 - 0.0032 17.2 13.7 0.01 15.6 13.7 1.8 1 1 0 1 1 1 1 Olfactory receptor Oxidored_q3 PF00499.20 OWF49275.1 - 0.0088 15.8 1.3 0.0088 15.8 1.3 1.9 3 0 0 3 3 3 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF898 PF05987.13 OWF49275.1 - 0.11 11.5 8.3 0.013 14.6 3.5 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Cation_ATPase_C PF00689.21 OWF49275.1 - 2.4 7.8 16.7 0.18 11.5 6.6 2.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus TMIE PF16038.5 OWF49276.1 - 0.024 14.5 0.2 0.033 14.0 0.2 1.2 1 0 0 1 1 1 0 TMIE protein SIT PF15330.6 OWF49276.1 - 0.044 14.2 0.1 0.1 13.1 0.1 1.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT RNA_pol_Rpb2_6 PF00562.28 OWF49277.1 - 1e-125 419.9 0.0 1.5e-125 419.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OWF49277.1 - 1.5e-68 230.4 0.0 2.1e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OWF49277.1 - 5.5e-55 185.9 0.0 1.1e-54 185.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OWF49277.1 - 4.7e-34 116.6 0.0 1.3e-33 115.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OWF49277.1 - 2.5e-24 85.2 0.0 6.1e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OWF49277.1 - 2.5e-23 82.1 1.2 7.6e-23 80.6 1.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OWF49277.1 - 6.9e-18 65.0 0.8 1.6e-17 63.8 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Amidoligase_2 PF12224.8 OWF49277.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative amidoligase enzyme Syndecan PF01034.20 OWF49278.1 - 0.026 14.5 0.8 0.051 13.5 0.8 1.4 1 0 0 1 1 1 0 Syndecan domain Chordopox_G3 PF06129.12 OWF49278.1 - 0.063 14.0 0.1 0.1 13.3 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Adeno_E3_CR2 PF02439.15 OWF49278.1 - 0.16 11.7 1.2 0.38 10.5 1.2 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2970 PF11174.8 OWF49278.1 - 4.6 7.2 8.1 37 4.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Peptidase_M13_N PF05649.13 OWF49279.1 - 1.3e-66 225.9 1.0 1.8e-66 225.4 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF49279.1 - 2.5e-58 197.1 0.0 5.9e-58 195.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 PgdA_N PF18627.1 OWF49280.1 - 0.036 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain DUF4094 PF13334.6 OWF49280.1 - 0.14 12.6 0.9 3.9 8.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Mitofilin PF09731.9 OWF49281.1 - 1.7e-101 341.0 61.2 8.1e-101 338.8 61.2 1.8 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DHOase PF12890.7 OWF49281.1 - 0.26 11.2 1.9 2.9 7.8 0.1 2.7 1 1 1 2 2 2 0 Dihydro-orotase-like TMEM215 PF15746.5 OWF49281.1 - 0.39 10.2 9.0 0.87 9.0 9.0 1.5 1 0 0 1 1 1 0 TMEM215 family Ribosomal_L35p PF01632.19 OWF49282.1 - 1.3e-13 51.2 1.3 2.4e-13 50.4 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 Fasciclin PF02469.22 OWF49283.1 - 3.8e-70 234.1 0.1 8.3e-34 116.6 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF1930 PF09122.10 OWF49283.1 - 0.034 14.1 0.6 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1930) LLC1 PF14945.6 OWF49284.1 - 3.5e-08 34.0 1.2 2.2e-07 31.4 0.6 2.0 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Leuk-A4-hydro_C PF09127.11 OWF49285.1 - 0.0011 19.0 7.8 47 4.1 0.1 7.1 1 1 4 7 7 7 0 Leukotriene A4 hydrolase, C-terminal DUF3094 PF11293.8 OWF49285.1 - 0.0012 18.5 29.8 28 4.5 0.1 12.0 4 3 7 12 12 12 1 Protein of unknown function (DUF3094) DUF4338 PF14236.6 OWF49285.1 - 0.084 12.1 5.1 20 4.3 0.4 4.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4338) KcnmB2_inactiv PF09303.10 OWF49285.1 - 4.5 7.2 8.0 90 3.0 0.1 4.9 4 0 0 4 4 4 0 KCNMB2, ball and chain domain Sh_2 PF17512.2 OWF49286.1 - 0.012 15.4 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein Phage_Gp23 PF10669.9 OWF49286.1 - 0.026 14.9 0.1 0.033 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) PRIMA1 PF16101.5 OWF49286.1 - 0.03 14.4 0.2 0.041 13.9 0.2 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4381 PF14316.6 OWF49286.1 - 0.03 14.6 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2844 PF11005.8 OWF49286.1 - 0.03 14.3 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) Herpes_gE PF02480.16 OWF49286.1 - 0.038 12.8 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SHR3_chaperone PF08229.11 OWF49286.1 - 0.044 12.8 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 OppC_N PF12911.7 OWF49286.1 - 0.083 12.9 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4834 PF16118.5 OWF49286.1 - 0.089 13.8 0.1 0.14 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1461 PF07314.11 OWF49286.1 - 0.09 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) UPF0542 PF15086.6 OWF49286.1 - 0.12 12.3 0.5 0.28 11.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Vpu PF00558.19 OWF49286.1 - 0.16 11.7 0.7 0.25 11.1 0.7 1.3 1 0 0 1 1 1 0 Vpu protein MTS PF05175.14 OWF49288.1 - 7.6e-09 35.3 0.0 2.5e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OWF49288.1 - 4.4e-06 27.3 0.0 9.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OWF49288.1 - 8.6e-05 22.1 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OWF49288.1 - 0.00044 21.0 0.0 0.0011 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF49288.1 - 0.0005 19.9 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF49288.1 - 0.019 15.6 0.0 0.058 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 OWF49288.1 - 0.075 14.1 0.0 0.18 12.9 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain DUF43 PF01861.16 OWF49288.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_16 PF10294.9 OWF49288.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 OWF49288.1 - 0.15 11.9 0.0 0.96 9.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 OWF49288.1 - 0.18 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ARD PF03079.14 OWF49289.1 - 2.6e-44 151.2 0.7 3.1e-44 150.9 0.7 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 OWF49289.1 - 4.2e-09 36.0 0.0 6.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OWF49289.1 - 2.7e-06 27.3 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OWF49289.1 - 0.0059 16.2 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 Cupin VHS PF00790.19 OWF49290.1 - 4.2e-37 127.1 0.0 1.8e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 OWF49290.1 - 3.4e-15 55.4 0.1 6.4e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF49290.1 - 2e-10 40.2 0.0 3.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OWF49290.1 - 1.3e-08 34.6 0.1 2.2e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 OWF49290.1 - 0.0001 21.9 1.1 0.00034 20.3 1.1 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Sigma54_CBD PF04963.13 OWF49290.1 - 0.0058 16.5 0.1 0.015 15.1 0.1 1.6 1 1 1 2 2 2 1 Sigma-54 factor, core binding domain GAT PF03127.14 OWF49290.1 - 0.043 14.1 0.8 0.11 12.8 0.8 1.8 1 0 0 1 1 1 0 GAT domain Tubulin_C PF03953.17 OWF49291.1 - 1.5e-48 164.1 0.0 4.4e-48 162.6 0.0 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin PF00091.25 OWF49291.1 - 2.2e-37 129.2 0.0 3.3e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 OWF49291.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Clc-like PF07062.12 OWF49292.1 - 0.0011 18.5 10.8 0.12 11.8 6.0 2.3 1 1 1 2 2 2 2 Clc-like Trp_oprn_chp PF09534.10 OWF49292.1 - 0.04 13.7 2.0 0.066 13.0 2.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4064 PF13273.6 OWF49292.1 - 1.1 9.5 10.2 7.5 6.9 6.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Tubulin PF00091.25 OWF49293.1 - 1.4e-67 227.7 0.0 1.9e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF49293.1 - 3e-49 166.4 0.0 4.9e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OWF49293.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Suf PF05843.14 OWF49294.1 - 0.13 12.2 0.4 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nucleo_P87 PF07267.11 OWF49294.1 - 0.53 9.1 2.7 0.61 8.9 2.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOG2 PF10428.9 OWF49294.1 - 0.73 9.0 7.5 0.96 8.6 7.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MSA-2c PF12238.8 OWF49294.1 - 0.99 9.4 7.0 1.7 8.6 7.0 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF4573 PF15140.6 OWF49296.1 - 0.022 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) EF-hand_1 PF00036.32 OWF49297.1 - 3.7e-34 113.7 17.9 5e-09 35.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF49297.1 - 1.3e-28 99.2 10.9 2.2e-14 53.7 2.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF49297.1 - 1.7e-26 89.8 11.0 4.1e-08 32.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF49297.1 - 1e-25 88.0 12.2 1.9e-07 30.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF49297.1 - 6.9e-25 86.7 16.2 3e-13 49.4 1.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF49297.1 - 3e-09 37.2 1.8 0.00042 20.6 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF49297.1 - 6.7e-09 35.6 6.8 0.0013 18.7 1.2 3.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF49297.1 - 1.4e-08 34.9 0.3 0.00035 20.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain TerB PF05099.13 OWF49297.1 - 2.8e-05 24.1 0.0 0.18 11.7 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 OWF49297.1 - 4.8e-05 23.5 4.3 0.56 10.4 0.2 3.7 2 2 2 4 4 4 3 Dockerin type I domain EF-hand_11 PF08976.11 OWF49297.1 - 0.0076 17.1 0.8 3.8 8.4 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 OWF49297.1 - 0.017 15.0 1.0 5.6 6.9 0.0 3.3 2 2 1 3 3 3 0 Caleosin related protein UPF0154 PF03672.13 OWF49297.1 - 0.099 12.7 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0154) RRM_1 PF00076.22 OWF49297.1 - 0.27 11.1 2.0 8.2 6.3 0.0 3.5 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_10 PF14788.6 OWF49297.1 - 0.82 9.6 4.4 7.3 6.5 0.3 3.3 2 2 2 4 4 4 0 EF hand VCBS PF13517.6 OWF49297.1 - 2.7 8.7 5.5 34 5.1 0.1 3.1 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 7tm_1 PF00001.21 OWF49298.1 - 5.4e-18 65.3 10.7 6.4e-18 65.0 10.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF456 PF04306.13 OWF49298.1 - 1.5 9.1 7.4 0.3 11.4 1.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF456) Wzy_C PF04932.15 OWF49298.1 - 5.6 6.6 8.1 62 3.2 8.1 2.3 1 1 0 1 1 1 0 O-Antigen ligase 7tm_1 PF00001.21 OWF49299.1 - 2.2e-24 86.2 4.9 2.8e-24 85.8 4.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4834 PF16118.5 OWF49299.1 - 0.0032 18.4 2.1 0.0047 17.9 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) DUF1201 PF06716.11 OWF49299.1 - 0.0064 16.5 0.6 0.026 14.5 0.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1201) CDC45 PF02724.14 OWF49299.1 - 0.18 10.0 1.6 1.2 7.4 0.1 2.0 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.6 OWF49299.1 - 0.27 10.9 1.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 FAM176 family Miff PF05644.11 OWF49300.1 - 1.7e-23 83.7 2.5 1.7e-17 64.0 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff REC114-like PF15165.6 OWF49301.1 - 9.8e-33 113.9 2.3 1.1e-17 64.6 0.3 2.0 1 1 1 2 2 2 2 Meiotic recombination protein REC114-like PCC_BT PF18140.1 OWF49301.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain 7tm_1 PF00001.21 OWF49302.1 - 3.4e-36 124.9 16.8 4.7e-36 124.5 16.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Lipase_GDSL_2 PF13472.6 OWF49302.1 - 0.056 13.8 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family 7tm_1 PF00001.21 OWF49303.1 - 4.5e-36 124.5 15.0 6.3e-36 124.1 15.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1772 PF08592.11 OWF49303.1 - 0.24 11.7 4.7 4.4 7.6 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) 7TM_GPCR_Srw PF10324.9 OWF49303.1 - 1 8.5 23.8 47 3.1 23.8 2.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Cadherin PF00028.17 OWF49306.1 - 2.4e-26 92.0 24.7 3e-08 34.0 0.9 7.4 7 0 0 7 7 7 7 Cadherin domain CopC PF04234.12 OWF49306.1 - 0.00086 20.3 3.2 0.0075 17.3 0.4 3.4 3 0 0 3 3 3 1 CopC domain DUF4625 PF15418.6 OWF49306.1 - 0.021 15.1 0.0 27 5.0 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4625) DUF5011 PF16403.5 OWF49306.1 - 0.49 10.6 5.8 13 6.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5011) Cadherin PF00028.17 OWF49309.1 - 3.4e-18 65.9 17.4 1.4e-08 35.0 0.5 6.5 6 2 0 6 6 6 3 Cadherin domain Cadherin_3 PF16184.5 OWF49309.1 - 0.00016 21.6 0.3 0.12 12.4 0.1 3.9 3 0 0 3 3 3 2 Cadherin-like A_deaminase PF00962.22 OWF49310.1 - 7.1e-72 242.5 0.0 8.8e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mpv17_PMP22 PF04117.12 OWF49312.1 - 3.6e-27 94.4 0.8 5.8e-27 93.7 0.8 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family GTP_EFTU PF00009.27 OWF49313.1 - 1e-55 188.3 0.0 1.5e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OWF49313.1 - 3.2e-38 130.5 0.0 8e-38 129.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OWF49313.1 - 1.8e-13 50.6 0.3 1.8e-13 50.6 0.3 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OWF49313.1 - 0.00063 19.8 0.1 0.02 15.0 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 OWF49313.1 - 0.0055 16.6 0.2 0.0055 16.6 0.2 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.12 OWF49313.1 - 0.0099 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OWF49313.1 - 0.023 14.4 0.2 12 5.7 0.0 3.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 OWF49313.1 - 0.12 12.4 0.1 24 4.9 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Ribosomal_S14 PF00253.21 OWF49314.1 - 7.3e-19 67.3 1.2 1e-18 66.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Kelch_1 PF01344.25 OWF49315.1 - 6.8e-77 252.9 13.6 1.9e-15 56.1 0.0 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 OWF49315.1 - 4.8e-42 140.9 8.0 3e-10 40.0 0.0 6.5 2 1 4 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OWF49315.1 - 9.7e-31 104.6 1.5 1.2e-07 31.4 0.0 6.7 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 OWF49315.1 - 2.2e-27 95.1 0.1 3.4e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 OWF49315.1 - 1.1e-26 92.5 6.4 3.5e-06 27.1 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 OWF49315.1 - 3.7e-26 91.5 0.0 9.2e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 OWF49315.1 - 6.3e-24 83.7 6.1 2e-05 24.5 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF49315.1 - 2e-13 50.0 8.2 0.0021 18.0 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Gp37 PF09646.10 OWF49315.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Gp37 protein DUF1896 PF08989.10 OWF49315.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) zf-C2H2 PF00096.26 OWF49316.1 - 4.2e-39 130.8 82.5 4.1e-05 23.8 0.7 11.8 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF49316.1 - 7.8e-39 130.4 71.5 2.7e-08 33.9 0.3 12.3 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF49316.1 - 7.5e-34 113.5 78.9 0.0032 18.2 0.6 11.7 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF49316.1 - 7.1e-12 45.0 67.9 0.13 12.3 0.8 11.6 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF49316.1 - 5.5e-07 29.7 58.8 0.13 12.6 0.3 11.3 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OWF49316.1 - 2.3e-05 24.1 34.0 0.048 13.4 0.8 7.7 7 0 0 7 7 7 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 OWF49316.1 - 2.5e-05 24.3 31.1 0.009 16.1 0.1 7.7 5 4 2 7 7 7 3 Zinc ribbon domain zf-met PF12874.7 OWF49316.1 - 0.00051 20.3 63.6 0.086 13.3 0.5 10.6 11 0 0 11 11 11 5 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF49316.1 - 0.0015 18.7 34.0 0.038 14.3 1.7 5.5 2 1 5 7 7 7 4 C2H2-type zinc ribbon BolA PF01722.18 OWF49316.1 - 0.36 11.2 7.0 17 5.8 0.1 4.9 4 3 1 5 5 5 0 BolA-like protein zf-MYST PF17772.1 OWF49316.1 - 0.37 10.4 32.9 4 7.1 0.1 8.9 6 3 4 10 10 10 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 OWF49316.1 - 0.54 11.0 39.4 0.4 11.5 2.0 6.3 1 1 8 9 9 9 0 zinc-ribbon family zf-H2C2_5 PF13909.6 OWF49316.1 - 0.6 9.9 0.0 0.6 9.9 0.0 9.7 11 1 0 11 11 11 0 C2H2-type zinc-finger domain Ta0938 PF11494.8 OWF49316.1 - 1.3 9.3 24.2 3.6 7.9 0.1 6.3 2 2 4 6 6 6 0 Ta0938 GAGA PF09237.11 OWF49316.1 - 6.8 6.6 17.9 42 4.1 0.0 6.3 4 1 3 7 7 7 0 GAGA factor zf-C2H2_4 PF13894.6 OWF49317.1 - 7.8e-26 88.5 49.6 0.0019 18.9 1.0 7.8 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF49317.1 - 8e-22 76.4 61.5 2.3e-05 24.6 1.8 8.1 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF49317.1 - 4.5e-20 71.1 53.5 1.9e-07 31.2 2.4 8.7 9 0 0 9 9 8 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF49317.1 - 2.7e-13 49.5 42.7 9.2e-05 22.3 0.3 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF49317.1 - 2.6e-11 43.5 31.7 0.081 13.2 0.0 7.7 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF49317.1 - 1.5e-05 25.3 44.6 0.031 14.6 11.3 5.7 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OWF49317.1 - 1.7e-05 25.0 33.2 0.011 16.1 0.2 7.4 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF49317.1 - 3e-05 24.2 41.8 0.0068 16.7 6.3 5.2 4 2 1 5 5 4 3 Drought induced 19 protein (Di19), zinc-binding IBD PF10416.9 OWF49317.1 - 0.0022 18.0 1.5 0.79 9.7 0.0 3.1 2 1 1 3 3 3 2 Transcription-initiator DNA-binding domain IBD zf-CHCC PF10276.9 OWF49317.1 - 0.0052 16.8 6.5 1.8 8.7 0.2 4.9 5 0 0 5 5 5 1 Zinc-finger domain Rad50_zn_hook PF04423.14 OWF49317.1 - 0.015 15.1 3.9 0.12 12.2 0.3 3.0 1 1 1 2 2 2 0 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 OWF49317.1 - 0.02 15.0 34.0 0.18 12.0 1.4 6.7 5 1 2 7 7 7 0 Zinc ribbon domain Spt46 PF17734.1 OWF49317.1 - 0.029 14.2 1.3 0.029 14.2 1.3 4.0 2 1 1 4 4 4 0 Spermatogenesis-associated protein 46 zf-C2H2_11 PF16622.5 OWF49317.1 - 0.045 13.5 37.6 0.27 11.0 0.6 7.6 8 0 0 8 8 8 0 zinc-finger C2H2-type DUF2709 PF10915.8 OWF49317.1 - 0.076 12.3 2.3 1.6 8.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2709) zinc_ribbon_9 PF14369.6 OWF49317.1 - 0.25 11.7 18.9 0.53 10.6 0.4 5.9 6 1 1 7 7 7 0 zinc-ribbon ADK_lid PF05191.14 OWF49317.1 - 0.46 10.5 20.8 0.71 9.9 1.4 5.4 3 1 2 5 5 4 0 Adenylate kinase, active site lid RNA_POL_M_15KD PF02150.16 OWF49317.1 - 2.2 8.2 10.5 3.7 7.5 0.0 4.8 4 1 1 5 5 5 0 RNA polymerases M/15 Kd subunit zf-RING_7 PF02591.15 OWF49317.1 - 2.5 8.4 14.3 0.23 11.7 1.6 4.1 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2H2_9 PF16293.5 OWF49317.1 - 3.7 7.5 19.4 2 8.3 0.2 5.8 4 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) LNS2 PF08235.13 OWF49318.1 - 2.2e-101 338.1 0.5 3.5e-101 337.4 0.2 1.5 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OWF49318.1 - 1.8e-42 143.4 0.0 4e-42 142.3 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 OWF49318.1 - 2.2e-31 108.0 0.1 5.8e-31 106.6 0.1 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 OWF49318.1 - 0.0047 17.8 0.2 0.0047 17.8 0.2 3.0 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box THEG4 PF15834.5 OWF49318.1 - 0.12 12.4 0.9 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Testis highly expressed protein 4 C2-set PF05790.15 OWF49318.1 - 0.71 10.1 3.6 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin C2-set domain BTB PF00651.31 OWF49319.1 - 2.9e-29 101.6 0.4 3.9e-27 94.7 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 OWF49319.1 - 1.2e-12 47.9 0.5 5.5e-12 45.7 0.5 2.1 1 1 0 1 1 1 1 BTB And C-terminal Kelch PHR PF08005.12 OWF49319.1 - 2.9e-10 41.0 0.0 6.5e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PHR domain Skp1_POZ PF03931.15 OWF49319.1 - 0.0066 16.6 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF4082 PF13313.6 OWF49319.1 - 0.12 12.4 0.2 0.3 11.1 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4082) BTB PF00651.31 OWF49320.1 - 1.6e-28 99.1 0.2 4e-27 94.6 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain PHR PF08005.12 OWF49320.1 - 1.2e-11 45.5 0.0 2.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 PHR domain BACK PF07707.15 OWF49320.1 - 1.8e-11 44.0 0.3 1.1e-10 41.5 0.2 2.3 2 1 0 2 2 2 1 BTB And C-terminal Kelch Skp1_POZ PF03931.15 OWF49320.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF4082 PF13313.6 OWF49320.1 - 0.054 13.5 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) BTB PF00651.31 OWF49321.1 - 2e-29 102.0 0.3 3.1e-27 95.0 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 OWF49321.1 - 2.3e-11 43.7 0.5 1.2e-10 41.4 0.3 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch PHR PF08005.12 OWF49321.1 - 2.4e-11 44.5 0.0 4.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 PHR domain DUF1207 PF06727.11 OWF49321.1 - 0.0061 15.5 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1207) Skp1_POZ PF03931.15 OWF49321.1 - 0.0078 16.4 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF3455 PF11937.8 OWF49321.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) BRE1 PF08647.11 OWF49322.1 - 0.015 15.3 9.9 0.015 15.3 9.9 3.8 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3037 PF11236.8 OWF49322.1 - 0.45 11.0 13.8 4 7.9 6.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) FUSC PF04632.12 OWF49322.1 - 0.71 8.3 7.9 1.1 7.7 7.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RFX_DNA_binding PF02257.15 OWF49323.1 - 3.3e-28 98.1 0.0 6.7e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain RFX5_N PF18326.1 OWF49323.1 - 2.6e-06 27.1 0.0 1e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 RFX5 N-terminal domain Pox_D5 PF03288.16 OWF49323.1 - 0.016 15.7 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF4471 PF14740.6 OWF49323.1 - 0.086 12.0 1.4 0.53 9.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Thioredoxin PF00085.20 OWF49324.1 - 6.4e-98 321.6 0.2 2.1e-24 85.5 0.0 6.3 6 0 0 6 6 6 6 Thioredoxin OST3_OST6 PF04756.13 OWF49324.1 - 3.5e-23 82.4 0.1 3.2e-07 30.0 0.1 4.5 2 1 2 4 4 4 4 OST3 / OST6 family, transporter family DnaJ PF00226.31 OWF49324.1 - 2.3e-20 72.5 3.8 4.4e-20 71.6 3.8 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_2 PF13098.6 OWF49324.1 - 3.2e-16 59.7 5.0 0.00057 20.3 0.1 6.4 6 2 0 6 6 6 4 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OWF49324.1 - 4.6e-14 52.5 1.3 0.087 13.2 0.0 6.1 5 1 1 6 6 6 3 Thioredoxin-like Thioredoxin_6 PF13848.6 OWF49324.1 - 1.7e-11 44.4 0.0 3.6e-05 23.8 0.0 4.4 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OWF49324.1 - 1e-08 35.2 5.6 0.0028 17.8 0.0 4.9 4 1 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 OWF49324.1 - 1.1e-08 35.1 4.9 0.055 13.4 0.0 5.0 5 0 0 5 5 5 3 AhpC/TSA family Redoxin PF08534.10 OWF49324.1 - 8.2e-08 32.1 1.9 0.19 11.4 0.0 4.0 4 0 0 4 4 4 3 Redoxin Thioredoxin_9 PF14595.6 OWF49324.1 - 5.5e-06 26.2 0.3 1.5 8.6 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_5 PF13743.6 OWF49324.1 - 0.00031 20.5 0.1 0.27 10.9 0.1 4.5 4 2 2 6 6 6 1 Thioredoxin Thioredoxin_3 PF13192.6 OWF49324.1 - 0.00044 20.3 5.2 0.53 10.4 0.0 4.3 5 0 0 5 5 5 2 Thioredoxin domain TraF PF13728.6 OWF49324.1 - 0.036 13.9 2.5 5.3 6.8 0.0 4.0 5 0 0 5 5 5 0 F plasmid transfer operon protein Gasdermin PF04598.12 OWF49325.1 - 3.8e-14 52.7 0.0 5.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Gasdermin pore forming domain TIP120 PF08623.10 OWF49325.1 - 0.041 13.7 1.5 0.063 13.0 0.5 1.8 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DPCD PF14913.6 OWF49326.1 - 6.3e-66 221.4 0.7 7.8e-66 221.1 0.1 1.4 2 0 0 2 2 2 1 DPCD protein family NusG_add PF18298.1 OWF49326.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 NusG additional domain zf-C3HC4_3 PF13920.6 OWF49327.1 - 3e-11 43.0 12.1 5.4e-11 42.2 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF49327.1 - 9.9e-06 25.3 12.0 2e-05 24.3 12.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OWF49327.1 - 0.00069 19.4 12.3 0.0016 18.3 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF49327.1 - 0.0081 16.1 14.2 0.014 15.3 14.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF49327.1 - 0.015 15.1 13.4 0.036 13.9 13.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF49327.1 - 0.044 13.8 12.3 0.077 13.0 7.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 OWF49327.1 - 0.053 13.9 14.5 0.096 13.0 14.5 1.5 1 0 0 1 1 1 0 Ring finger domain Baculo_IE-1 PF05290.11 OWF49327.1 - 0.19 11.6 3.5 0.31 11.0 3.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 OWF49327.1 - 5.9 7.1 11.4 13 6.0 11.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OWF49327.1 - 8.2 6.6 10.2 19 5.4 3.9 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger rve PF00665.26 OWF49328.1 - 0.00046 20.4 0.0 0.0013 18.9 0.0 1.7 1 1 0 1 1 1 1 Integrase core domain DDE_1 PF03184.19 OWF49329.1 - 5.5e-27 94.5 0.0 7.1e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OWF49329.1 - 0.0039 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 OWF49330.1 - 3.6e-11 42.6 0.0 5.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 OWF49330.1 - 3.9e-05 23.7 0.1 0.00022 21.2 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 OWF49330.1 - 0.00027 20.9 0.1 0.00046 20.2 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_7 PF02796.15 OWF49330.1 - 0.019 15.0 0.1 0.22 11.6 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 OWF49330.1 - 0.022 14.4 0.0 0.07 12.8 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 OWF49330.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 OWF49330.1 - 0.11 12.3 0.1 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain REPA_OB_2 PF16900.5 OWF49331.1 - 0.0003 20.7 0.6 0.0081 16.1 0.1 2.5 2 0 0 2 2 2 1 Replication protein A OB domain HypA PF01155.19 OWF49331.1 - 0.033 14.2 1.1 0.063 13.3 1.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 OWF49331.1 - 0.14 12.1 1.5 11 6.1 0.2 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain TFIIS_C PF01096.18 OWF49331.1 - 3.8 7.4 7.4 16 5.4 1.0 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Bcl-2 PF00452.19 OWF49332.1 - 4.5e-13 49.7 0.3 7.8e-13 49.0 0.3 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Bcl-2_BAD PF10514.9 OWF49332.1 - 0.065 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD ATG27 PF09451.10 OWF49333.1 - 2.1e-15 57.3 0.7 2.8e-15 56.9 0.7 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF49333.1 - 1.3e-11 44.1 0.2 2.1e-11 43.4 0.2 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PalH PF08733.10 OWF49334.1 - 0.0049 15.9 0.2 0.0049 15.9 0.2 2.2 2 0 0 2 2 2 1 PalH/RIM21 Lon_C PF05362.13 OWF49335.1 - 2e-69 233.3 0.0 4.4e-69 232.1 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OWF49335.1 - 3.3e-24 85.9 14.1 3.3e-24 85.9 14.1 2.1 2 1 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OWF49335.1 - 8.1e-23 81.3 0.0 3.9e-22 79.1 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF49335.1 - 3.5e-10 40.0 0.0 3.1e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OWF49335.1 - 3.6e-09 37.0 0.6 2.3e-08 34.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 OWF49335.1 - 4.8e-07 29.6 0.1 9.9e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 OWF49335.1 - 3.6e-06 27.5 0.1 5e-05 23.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 OWF49335.1 - 1.1e-05 24.6 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 OWF49335.1 - 3.2e-05 24.2 0.6 0.00094 19.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OWF49335.1 - 5.2e-05 23.1 0.0 0.00022 21.0 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OWF49335.1 - 0.0014 18.7 2.0 0.0047 17.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 OWF49335.1 - 0.0019 18.6 0.0 0.0099 16.3 0.0 2.3 2 0 0 2 2 1 1 RNA helicase IstB_IS21 PF01695.17 OWF49335.1 - 0.0079 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein NB-ARC PF00931.22 OWF49335.1 - 0.0084 15.3 0.0 0.023 13.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 OWF49335.1 - 0.013 15.5 0.0 0.087 12.7 0.0 2.6 2 1 0 2 2 1 0 NACHT domain AAA_33 PF13671.6 OWF49335.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OWF49335.1 - 0.036 14.0 0.3 0.31 10.9 0.0 2.6 2 1 1 3 3 3 0 NTPase RsgA_GTPase PF03193.16 OWF49335.1 - 0.039 13.8 0.0 0.19 11.6 0.0 2.2 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 OWF49335.1 - 0.045 13.3 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OWF49335.1 - 0.049 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OWF49335.1 - 0.065 13.1 0.0 0.23 11.3 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OWF49335.1 - 0.072 13.6 0.0 0.072 13.6 0.0 3.6 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.6 OWF49335.1 - 0.075 13.6 0.0 0.075 13.6 0.0 2.5 3 0 0 3 3 1 0 AAA domain TsaE PF02367.17 OWF49335.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF720 PF05302.11 OWF49335.1 - 0.15 11.9 0.3 0.34 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Thr_synth_N PF14821.6 OWF49335.1 - 0.16 12.2 0.2 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus ABC_tran PF00005.27 OWF49335.1 - 0.25 11.9 2.8 0.54 10.8 0.0 2.8 3 0 0 3 3 2 0 ABC transporter AAA_11 PF13086.6 OWF49335.1 - 0.43 10.3 7.1 0.66 9.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF45 PF01863.17 OWF49335.1 - 0.56 10.2 5.5 23 5.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF45 Cytidylate_kin PF02224.18 OWF49335.1 - 0.73 9.5 0.0 0.73 9.5 0.0 3.2 4 0 0 4 4 4 0 Cytidylate kinase SKI PF01202.22 OWF49335.1 - 1.2 9.2 4.8 2.3 8.3 0.0 3.4 3 0 0 3 3 3 0 Shikimate kinase C2 PF00168.30 OWF49337.1 - 3.5e-49 165.4 0.0 1.2e-25 89.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 OWF49337.1 - 0.00018 21.1 0.0 0.00051 19.6 0.0 1.8 2 0 0 2 2 2 1 CEP76 C2 domain Shisa PF13908.6 OWF49337.1 - 0.012 15.9 0.2 0.02 15.1 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 OWF49337.1 - 0.075 12.8 2.1 0.14 11.9 2.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CD34_antigen PF06365.12 OWF49337.1 - 0.08 12.5 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 OWF49337.1 - 0.1 13.5 0.0 0.3 12.0 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.6 OWF49337.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 SCIMP protein RCR PF12273.8 OWF49337.1 - 0.15 12.7 0.0 0.34 11.6 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Recep_L_domain PF01030.24 OWF49338.1 - 1e-50 170.5 302.9 15 5.8 0.3 83.0 1 1 99 100 100 100 99 Receptor L domain DUF3821 PF12863.7 OWF49338.1 - 5e-22 78.8 147.5 3.8 7.3 0.1 32.1 1 1 56 57 57 57 57 Domain of unknown function (DUF3821) Ependymin PF00811.18 OWF49339.1 - 0.00075 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF49340.1 - 6.7e-05 23.1 0.8 0.00072 19.8 0.8 2.1 1 1 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF49341.1 - 4.5e-06 26.9 0.8 4.4e-05 23.7 0.8 2.1 1 1 0 1 1 1 1 Ependymin ECR1_N PF14382.6 OWF49341.1 - 0.054 13.3 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Ependymin PF00811.18 OWF49342.1 - 2.1e-06 28.0 0.1 7.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Ependymin Ependymin PF00811.18 OWF49343.1 - 0.00021 21.6 0.4 0.0012 19.1 0.4 2.0 1 1 0 1 1 1 1 Ependymin Ependymin PF00811.18 OWF49344.1 - 0.00041 20.6 1.0 0.0014 18.9 1.0 1.9 1 1 0 1 1 1 1 Ependymin PARP_regulatory PF01358.18 OWF49344.1 - 0.047 12.6 1.9 0.059 12.3 0.7 1.6 2 0 0 2 2 2 0 Poly A polymerase regulatory subunit SH2 PF00017.24 OWF49346.1 - 5.5e-08 32.8 0.0 6.7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Mab-21 PF03281.14 OWF49347.1 - 7.7e-20 71.4 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Mab-21 protein ASC PF00858.24 OWF49348.1 - 1.5e-49 169.2 7.1 1.5e-49 169.2 7.1 1.4 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel Tox-ODYAM1 PF15642.6 OWF49348.1 - 0.12 11.4 0.3 0.25 10.3 0.3 1.4 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Peptidase_M28 PF04389.17 OWF49349.1 - 2.5e-14 53.4 0.0 4.6e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 OWF49349.1 - 2.2e-06 27.3 0.0 5.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Nicastrin zf-BED PF02892.15 OWF49351.1 - 1.4 9.0 5.6 24 5.0 0.1 3.0 3 0 0 3 3 3 0 BED zinc finger DUF1176 PF06674.11 OWF49352.1 - 0.12 11.7 0.7 0.19 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Macoilin PF09726.9 OWF49352.1 - 1.1 7.7 8.0 1.4 7.4 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Axin_b-cat_bind PF08833.10 OWF49352.1 - 6.4 7.0 6.8 14 5.9 0.2 2.7 2 0 0 2 2 2 0 Axin beta-catenin binding domain RIIa PF02197.17 OWF49354.1 - 0.00021 20.9 0.1 0.00021 20.9 0.1 1.8 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Ig_3 PF13927.6 OWF49355.1 - 1.6e-31 108.8 21.5 4.6e-11 43.2 0.1 6.8 7 0 0 7 7 7 4 Immunoglobulin domain I-set PF07679.16 OWF49355.1 - 1.7e-22 79.3 4.5 1.6e-06 28.1 0.0 7.1 6 1 0 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF49355.1 - 3.2e-18 65.8 12.3 1.6e-05 25.1 0.1 6.5 7 0 0 7 7 7 4 Immunoglobulin domain fn3 PF00041.21 OWF49355.1 - 1.3e-13 51.0 1.5 1.6e-12 47.5 0.1 3.3 4 0 0 4 4 4 1 Fibronectin type III domain ig PF00047.25 OWF49355.1 - 2e-12 47.1 15.2 6.1e-05 23.1 0.1 5.6 5 1 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 OWF49355.1 - 2.3e-08 34.0 11.4 0.0041 17.2 0.7 4.3 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF49355.1 - 0.011 15.9 15.2 0.037 14.2 0.1 5.3 6 1 1 7 7 7 0 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF49355.1 - 0.067 13.3 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain C2-set PF05790.15 OWF49355.1 - 0.1 12.8 0.2 27 5.0 0.0 3.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain FYVE PF01363.21 OWF49356.1 - 0.03 14.5 9.0 0.078 13.1 9.1 1.7 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.7 OWF49356.1 - 0.069 13.2 8.9 2.2 8.4 3.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 OWF49356.1 - 0.097 12.6 11.8 0.73 9.8 11.2 2.3 1 1 1 2 2 2 0 PHD-finger zf-AN1 PF01428.16 OWF49356.1 - 0.33 11.2 10.9 3 8.1 6.6 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger DUF4637 PF15470.6 OWF49356.1 - 0.85 9.3 9.3 3.3 7.4 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) LRR_4 PF12799.7 OWF49357.1 - 0.00011 22.6 12.6 1 9.9 2.9 5.8 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF49357.1 - 0.00011 21.9 10.8 0.016 15.0 4.5 5.0 4 2 1 5 5 5 2 Leucine rich repeat Arm PF00514.23 OWF49357.1 - 0.00096 19.1 8.0 4.2 7.6 0.1 7.1 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat LRR_6 PF13516.6 OWF49357.1 - 0.0012 18.7 8.9 6 7.2 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 OWF49357.1 - 0.0021 18.3 11.9 1.4 9.7 0.7 6.5 6 0 0 6 6 6 1 Leucine Rich Repeat DUF3361 PF11841.8 OWF49357.1 - 0.1 12.5 0.0 7 6.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Laminin_G_3 PF13385.6 OWF49358.1 - 3.3e-21 76.0 0.0 6.6e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sushi PF00084.20 OWF49358.1 - 3.3e-14 53.2 41.9 6.2e-06 26.7 1.6 6.5 7 0 0 7 7 7 4 Sushi repeat (SCR repeat) Peptidase_M43 PF05572.13 OWF49358.1 - 6.9e-05 22.8 1.5 0.0001 22.2 0.1 2.0 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Pentaxin PF00354.17 OWF49358.1 - 0.0022 17.7 0.1 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Pentaxin family Notch PF00066.17 OWF49358.1 - 0.0055 17.1 9.4 0.0055 17.1 9.4 6.9 6 0 0 6 6 6 3 LNR domain Laminin_G_2 PF02210.24 OWF49358.1 - 0.0058 17.2 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain DUF1080 PF06439.11 OWF49358.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) Peptidase_M54 PF07998.11 OWF49358.1 - 0.13 12.3 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Peptidase family M54 I-set PF07679.16 OWF49359.1 - 3e-90 296.4 0.0 4.2e-17 62.0 0.0 8.8 8 0 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF49359.1 - 1.9e-88 291.1 0.3 3.4e-11 43.6 0.0 10.0 10 0 0 10 10 10 8 Immunoglobulin domain fn3 PF00041.21 OWF49359.1 - 4.2e-60 200.1 11.5 2.5e-13 50.2 0.0 6.6 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.6 OWF49359.1 - 1.7e-59 198.1 0.1 9.8e-10 38.6 0.0 8.7 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 OWF49359.1 - 9.8e-50 166.7 0.0 8.2e-06 25.9 0.0 9.6 8 2 0 8 8 8 8 Immunoglobulin domain C2-set_2 PF08205.12 OWF49359.1 - 9.5e-21 73.7 0.0 0.00025 21.0 0.0 7.7 7 0 0 7 7 7 6 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF49359.1 - 5.6e-20 71.5 10.2 0.0071 16.5 0.1 11.9 8 6 2 10 10 10 5 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF49359.1 - 7.1e-07 28.7 0.0 10 5.8 0.0 6.8 7 0 0 7 7 7 1 Immunoglobulin domain V-set_CD47 PF08204.11 OWF49359.1 - 1.3e-05 25.1 0.0 1.1 9.2 0.0 5.8 6 0 0 6 6 6 1 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 OWF49359.1 - 0.039 14.0 0.0 63 3.7 0.0 4.3 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 OWF49359.1 - 0.067 13.0 0.3 2.4 8.0 0.1 3.3 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Orn_Arg_deC_N PF02784.16 OWF49360.1 - 3.2e-70 236.3 0.0 4.4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OWF49360.1 - 6.7e-10 39.1 0.0 1.4e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-C2H2_4 PF13894.6 OWF49361.1 - 0.093 13.6 15.5 0.09 13.7 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF49361.1 - 0.12 12.8 21.8 0.26 11.8 2.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 OWF49361.1 - 0.26 11.6 8.7 6.2 7.2 7.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 OWF49361.1 - 3.8 8.1 5.0 9.2 6.9 5.0 1.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-met PF12874.7 OWF49361.1 - 5.2 7.6 11.0 5.8 7.4 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DFP PF04127.15 OWF49362.1 - 3.7e-21 75.8 0.0 2.4e-12 47.1 0.1 2.2 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein SIMPL PF04402.14 OWF49362.1 - 0.052 14.0 0.1 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF541) ECH_2 PF16113.5 OWF49363.1 - 1.4e-127 425.8 0.0 1.6e-127 425.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OWF49363.1 - 3.1e-28 98.7 0.0 6.3e-28 97.8 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase SNF PF00209.18 OWF49364.1 - 4.6e-171 570.1 36.4 7e-171 569.5 36.4 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF49365.1 - 2.3e-165 551.3 40.5 7.7e-120 401.0 19.2 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 OWF49365.1 - 1.7 7.9 6.8 0.16 11.3 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) adh_short_C2 PF13561.6 OWF49366.1 - 1.8e-50 171.7 0.1 2.3e-50 171.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF49366.1 - 7.5e-45 152.8 0.5 9.5e-45 152.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF49366.1 - 3.7e-07 30.2 0.2 7.1e-07 29.3 0.1 1.5 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 OWF49366.1 - 9e-05 23.0 0.1 0.00017 22.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OWF49366.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OWF49366.1 - 0.00028 21.0 0.1 0.00044 20.3 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 OWF49366.1 - 0.0066 15.6 0.2 0.01 15.0 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OWF49366.1 - 0.0095 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 OWF49366.1 - 0.015 15.2 0.0 0.042 13.8 0.0 1.7 1 1 1 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OWF49366.1 - 0.026 13.9 0.0 0.065 12.6 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OWF49366.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 OWF49366.1 - 0.041 12.9 0.1 0.056 12.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OWF49366.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 OWF49367.1 - 4.5e-34 118.0 0.0 6.4e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49367.1 - 5.4e-24 84.9 0.0 5.4e-23 81.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF49367.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Zip PF02535.22 OWF49368.1 - 6.6e-63 212.9 14.5 6.6e-63 212.9 14.5 3.4 2 1 0 2 2 2 1 ZIP Zinc transporter SPX PF03105.19 OWF49368.1 - 0.93 9.3 11.6 1.6 8.5 11.6 1.4 1 0 0 1 1 1 0 SPX domain DAZAP2 PF11029.8 OWF49369.1 - 1.9e-19 70.9 40.6 3.1e-18 67.0 40.6 2.0 1 1 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) Cullin PF00888.22 OWF49370.1 - 1.3e-199 664.8 16.5 1.3e-199 664.8 16.5 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 OWF49370.1 - 9.8e-28 96.0 5.8 9e-27 92.9 3.6 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 OWF49370.1 - 0.0082 16.5 0.1 0.038 14.4 0.1 2.2 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC Acyl-ACP_TE PF01643.17 OWF49371.1 - 9.7e-08 31.6 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF49371.1 - 6.8e-05 23.3 0.9 0.0012 19.3 0.4 2.4 2 1 0 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.22 OWF49371.1 - 0.073 13.4 0.2 2.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Thioesterase superfamily YscK PF06578.12 OWF49372.1 - 0.032 13.7 8.4 1.7 8.1 1.2 3.4 1 1 1 2 2 2 0 YOP proteins translocation protein K (YscK) PAC4 PF16093.5 OWF49372.1 - 0.12 12.6 3.6 61 3.9 3.6 3.2 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 DUF2390 PF09523.10 OWF49372.1 - 0.24 11.7 2.2 2 8.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) Bcl-2 PF00452.19 OWF49372.1 - 0.63 10.8 5.6 6.4 7.5 0.9 2.8 1 1 2 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Sulfotransfer_1 PF00685.27 OWF49373.1 - 2.1e-26 93.0 0.2 2.7e-26 92.6 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF49373.1 - 6.2e-14 52.9 0.1 9.1e-09 36.0 0.1 2.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF49373.1 - 0.01 15.8 0.4 0.018 15.0 0.4 1.4 1 0 0 1 1 1 0 Sulfotransferase family DUF446 PF04287.12 OWF49374.1 - 8.9e-57 189.2 146.9 7.9 6.6 0.0 62.1 1 1 84 85 85 85 32 tRNA pseudouridine synthase C Med31 PF05669.12 OWF49374.1 - 3e-15 56.0 374.5 1e+02 3.0 8.8 41.9 1 1 9 10 10 10 0 SOH1 DUF166 PF02593.14 OWF49374.1 - 8.7e-10 38.5 27.8 51 3.3 0.2 18.6 1 1 20 21 21 21 1 Domain of unknown function Keratin_B2_2 PF13885.6 OWF49375.1 - 0.0011 18.9 1.0 0.038 13.9 1.2 2.5 1 1 0 1 1 1 1 Keratin, high sulfur B2 protein PMG PF05287.12 OWF49375.1 - 0.0024 18.0 0.4 0.0046 17.0 0.4 1.5 1 1 0 1 1 1 1 PMG protein TRAM_LAG1_CLN8 PF03798.16 OWF49375.1 - 0.0043 16.8 0.3 0.37 10.5 0.1 2.1 1 1 1 2 2 2 2 TLC domain Keratin_B2 PF01500.17 OWF49375.1 - 0.1 12.6 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein U3snoRNP10 PF12397.8 OWF49376.1 - 0.0095 16.3 10.1 0.069 13.5 2.2 2.6 1 1 2 3 3 3 2 U3 small nucleolar RNA-associated protein 10 Flu_M2 PF00599.17 OWF49376.1 - 0.3 11.2 4.4 8.7 6.5 0.1 3.4 2 2 2 4 4 4 0 Influenza Matrix protein (M2) Chordopox_G3 PF06129.12 OWF49376.1 - 2.2 9.0 7.5 8.7 7.1 0.7 3.3 1 1 2 3 3 3 0 Chordopoxvirus G3 protein Med20 PF08612.11 OWF49377.1 - 0.091 12.1 9.6 0.11 11.9 9.6 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Lant_dehydr_C PF14028.6 OWF49378.1 - 0.17 11.4 2.3 0.22 11.0 2.3 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term HTH_48 PF17906.1 OWF49378.1 - 0.18 12.0 5.7 37 4.5 0.1 4.2 1 1 3 4 4 4 0 HTH domain in Mos1 transposase Aft1_OSA PF11785.8 OWF49378.1 - 0.19 12.2 7.0 3.2 8.2 0.1 3.7 3 1 1 4 4 4 0 Aft1 osmotic stress response (OSM) domain THAP PF05485.12 OWF49379.1 - 4.6e-16 59.5 0.2 4.6e-16 59.5 0.2 1.4 2 0 0 2 2 2 1 THAP domain Sulfotransfer_1 PF00685.27 OWF49380.1 - 9e-28 97.5 0.4 1.2e-27 97.0 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF49380.1 - 1.6e-09 38.5 0.0 2.9e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF49380.1 - 0.022 14.7 0.2 0.042 13.8 0.2 1.7 1 1 0 1 1 1 0 Sulfotransferase family Nrf1_DNA-bind PF10491.9 OWF49381.1 - 6.8e-14 52.1 0.2 2.2e-13 50.4 0.1 1.9 1 1 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 zf-MYST PF17772.1 OWF49381.1 - 0.0087 15.6 1.2 0.023 14.3 1.2 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain DUF2841 PF11001.8 OWF49381.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) zf-C2H2_jaz PF12171.8 OWF49381.1 - 0.23 11.8 1.4 0.65 10.3 1.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RhoGAP PF00620.27 OWF49382.1 - 3.9e-44 150.1 0.0 2.6e-43 147.5 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 OWF49382.1 - 1.8e-14 53.8 4.0 1.8e-14 53.8 4.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 OWF49382.1 - 3.9e-14 52.0 0.1 7.5e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF49382.1 - 2.8e-08 33.3 0.0 5.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OWF49382.1 - 4.8e-07 29.5 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4164 PF13747.6 OWF49382.1 - 9.6 6.6 13.0 0.039 14.2 1.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) FAM72 PF14976.6 OWF49383.1 - 3.5e-51 173.2 5.9 3.9e-51 173.0 5.9 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 OWF49383.1 - 0.09 13.0 7.7 0.21 11.8 7.8 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4486 PF14858.6 OWF49384.1 - 1.6e-226 753.1 0.0 2.4e-226 752.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) DUF908 PF06012.12 OWF49384.1 - 0.0021 17.5 3.3 0.0067 15.9 0.1 3.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) fn3 PF00041.21 OWF49384.1 - 0.0047 17.3 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain CYYR1 PF10873.8 OWF49386.1 - 0.03 14.7 7.5 0.048 14.1 7.5 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF4229 PF14012.6 OWF49386.1 - 0.079 13.1 0.1 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FAM176 PF14851.6 OWF49387.1 - 0.0075 15.9 7.4 1.7 8.3 8.2 2.3 2 0 0 2 2 2 1 FAM176 family Glycophorin_A PF01102.18 OWF49387.1 - 0.025 14.8 3.1 0.071 13.4 2.0 2.3 1 1 0 1 1 1 0 Glycophorin A SKG6 PF08693.10 OWF49387.1 - 0.13 11.7 0.3 0.32 10.4 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MAP17 PF15807.5 OWF49387.1 - 0.19 12.0 5.4 4 7.7 0.0 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Peptidase_S64 PF08192.11 OWF49387.1 - 0.61 8.5 6.3 0.86 8.0 6.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 PBP1_TM PF14812.6 OWF49387.1 - 1.8 9.0 17.0 4.1 7.8 17.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OWF49387.1 - 2 6.6 11.6 2.9 6.1 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 OWF49387.1 - 6.8 5.4 11.3 13 4.4 11.2 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MAP17 PF15807.5 OWF49388.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 OWF49388.1 - 0.16 12.8 0.1 0.7 10.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OWF49388.1 - 0.18 12.1 2.1 0.34 11.1 1.9 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF49389.1 - 0.014 16.3 0.1 0.047 14.6 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Histone PF00125.24 OWF49389.1 - 0.027 14.8 4.7 0.059 13.7 0.0 2.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Linker_histone PF00538.19 OWF49389.1 - 0.056 13.8 0.9 0.15 12.4 0.9 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family Ras PF00071.22 OWF49391.1 - 1.2e-18 67.2 0.4 1.5e-18 66.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF49391.1 - 0.011 15.9 0.1 0.023 14.9 0.0 1.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF49391.1 - 0.02 14.4 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family zf-C2H2_4 PF13894.6 OWF49392.1 - 2.6 9.1 6.8 29 5.9 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2HC_14 PF18574.1 OWF49392.1 - 4.9 7.0 7.8 0.77 9.6 1.3 2.6 3 0 0 3 3 3 0 C2HC Zing finger domain AMP_N PF05195.16 OWF49393.1 - 0.052 13.3 0.1 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain CWC25 PF12542.8 OWF49393.1 - 0.099 13.6 2.9 0.38 11.7 2.9 1.9 1 1 0 1 1 1 0 Pre-mRNA splicing factor Lipase_GDSL_2 PF13472.6 OWF49394.1 - 7.4e-06 26.5 0.0 8.9e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family 7tm_1 PF00001.21 OWF49395.1 - 5.6e-16 58.7 16.8 7.5e-16 58.2 16.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF49395.1 - 5.9e-15 55.4 23.4 1.4e-14 54.1 23.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF49395.1 - 2.8e-09 36.7 23.6 0.00014 21.3 9.0 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF49395.1 - 4.2e-05 23.3 10.8 4.2e-05 23.3 10.8 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 OWF49396.1 - 4.2e-16 59.1 17.3 5.8e-16 58.6 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF49396.1 - 1.1e-13 51.1 22.9 3.9e-13 49.4 22.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF49396.1 - 1.3e-08 34.6 20.4 5.1e-07 29.3 20.4 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF49397.1 - 7.3e-16 58.3 17.0 9.9e-16 57.8 17.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF49397.1 - 3.4e-15 56.1 24.0 8e-15 54.9 24.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF49397.1 - 2.2e-09 37.1 24.5 6.3e-07 29.0 24.5 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF49397.1 - 3.9e-05 23.4 12.4 3.9e-05 23.4 12.4 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2985 PF11204.8 OWF49397.1 - 0.72 10.0 6.1 0.12 12.6 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) 7tm_1 PF00001.21 OWF49398.1 - 1.3e-16 60.8 17.6 1.8e-16 60.3 17.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF49398.1 - 3.9e-14 52.7 23.7 1.2e-13 51.1 23.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF49398.1 - 8.8e-09 35.1 21.9 3.5e-07 29.9 21.9 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Sru PF10322.9 OWF49398.1 - 0.071 12.4 20.2 0.014 14.7 13.2 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF3143 PF11341.8 OWF49402.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Cu_amine_oxid PF01179.20 OWF49403.1 - 9.3e-109 364.1 0.2 1.5e-108 363.4 0.2 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OWF49403.1 - 1.2e-05 25.6 0.2 3.6e-05 24.1 0.2 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OWF49403.1 - 0.001 19.2 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 OWF49403.1 - 0.018 14.8 0.1 0.052 13.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) C2 PF00168.30 OWF49404.1 - 6.2e-25 87.5 0.1 6.1e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain EphA2_TM PF14575.6 OWF49404.1 - 0.039 14.8 0.0 0.086 13.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CEP76-C2 PF15627.6 OWF49404.1 - 0.072 12.7 0.2 0.81 9.2 0.1 2.4 2 1 0 2 2 2 0 CEP76 C2 domain Cadherin_C_2 PF16492.5 OWF49404.1 - 0.087 13.6 0.1 22 5.9 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Adeno_E3_CR2 PF02439.15 OWF49404.1 - 0.17 11.7 0.6 0.31 10.8 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Filamin PF00630.19 OWF49406.1 - 2.8e-98 323.6 6.8 5.8e-12 46.3 0.0 9.5 10 0 0 10 10 10 9 Filamin/ABP280 repeat Y_Y_Y PF07495.13 OWF49406.1 - 1.3e-10 41.0 0.5 0.24 11.4 0.1 6.3 6 0 0 6 6 6 4 Y_Y_Y domain DUF5060 PF16586.5 OWF49406.1 - 0.0037 17.6 0.0 35 4.9 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF5060) PapC_N PF13954.6 OWF49406.1 - 0.014 15.4 0.0 12 5.9 0.0 3.8 5 0 0 5 5 5 0 PapC N-terminal domain Gryzun-like PF12742.7 OWF49406.1 - 0.18 11.8 0.0 14 5.8 0.0 3.3 3 0 0 3 3 3 0 Gryzun, putative Golgi trafficking Mito_carr PF00153.27 OWF49407.1 - 1.6e-61 204.2 2.0 1.7e-19 69.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF49407.1 - 0.0041 16.3 1.3 0.11 11.6 0.1 3.0 2 1 3 5 5 5 1 Gammaproteobacterial serine protease SSF PF00474.17 OWF49408.1 - 2.8e-29 102.2 20.7 1.2e-28 100.2 19.7 1.9 1 1 1 2 2 2 2 Sodium:solute symporter family 7tm_2 PF00002.24 OWF49409.1 - 1.1e-28 100.1 18.4 2.2e-28 99.2 18.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_3 PF13385.6 OWF49409.1 - 3.3e-12 46.8 0.6 6.1e-12 45.9 0.6 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 OWF49409.1 - 1.2e-11 44.7 0.1 3.1e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Pentaxin family GAIN PF16489.5 OWF49409.1 - 2.6e-10 40.1 0.1 5.5e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain HRM PF02793.22 OWF49409.1 - 0.00024 21.3 0.6 0.00064 20.0 0.6 1.8 1 0 0 1 1 1 1 Hormone receptor domain TauE PF01925.19 OWF49409.1 - 0.096 12.3 7.2 2.5 7.7 0.1 2.7 3 0 0 3 3 3 0 Sulfite exporter TauE/SafE FXa_inhibition PF14670.6 OWF49409.1 - 2.2 8.6 5.2 7 7.0 5.2 1.8 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site LHC PF00556.20 OWF49409.1 - 3.1 8.1 5.6 2.7 8.3 0.4 2.9 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit zf-RING_2 PF13639.6 OWF49410.1 - 1e-14 54.6 5.6 1.5e-14 54.0 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF49410.1 - 8.8e-12 44.7 5.9 1.5e-11 43.9 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF49410.1 - 9.5e-10 38.2 4.1 1.5e-09 37.5 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF49410.1 - 2e-09 37.0 1.8 2e-09 37.0 1.8 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OWF49410.1 - 3.7e-09 36.7 7.6 1e-08 35.3 7.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF49410.1 - 8.1e-08 32.2 1.6 8.1e-08 32.2 1.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 OWF49410.1 - 2.8e-06 27.1 2.7 0.029 14.2 0.2 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_5 PF14634.6 OWF49410.1 - 3.1e-06 27.0 3.6 4.9e-06 26.4 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF49410.1 - 9.4e-06 25.6 1.1 1.6e-05 24.9 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OWF49410.1 - 0.00024 20.9 5.1 0.00051 19.9 5.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF49410.1 - 0.00036 20.3 3.5 0.00036 20.3 3.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF49410.1 - 0.0013 18.5 3.7 0.0022 17.7 3.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OWF49410.1 - 0.0024 18.0 3.8 0.0065 16.6 3.8 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OWF49410.1 - 0.0037 17.4 3.3 0.028 14.6 3.3 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 OWF49410.1 - 0.0068 16.3 1.8 0.38 10.7 0.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-Nse PF11789.8 OWF49410.1 - 0.046 13.5 2.0 0.084 12.7 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OWF49410.1 - 0.33 11.1 4.1 0.81 9.9 4.1 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 OWF49410.1 - 0.67 9.9 4.6 1.7 8.6 4.6 1.7 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 OWF49410.1 - 1.5 8.5 5.3 4.3 7.0 5.3 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OWF49410.1 - 3.5 8.0 5.7 1.9 8.9 1.4 2.1 2 0 0 2 2 2 0 RING-like domain UPF0547 PF10571.9 OWF49410.1 - 4.7 7.4 10.8 2.3 8.4 0.2 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zip PF02535.22 OWF49411.1 - 3.9e-32 111.8 0.1 4.9e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4212 PF13937.6 OWF49411.1 - 8.4 6.9 7.0 0.41 11.1 0.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) MTBP_C PF14920.6 OWF49412.1 - 2.5e-22 79.9 15.6 2.5e-22 79.9 15.6 2.5 1 1 1 2 2 2 1 MDM2-binding MTBP_mid PF14919.6 OWF49412.1 - 2.2e-21 76.5 0.2 1e-20 74.2 0.1 2.0 2 0 0 2 2 2 1 MDM2-binding MTBP_N PF14918.6 OWF49412.1 - 1.5e-07 31.2 0.1 5.8e-07 29.2 0.0 2.0 2 1 0 2 2 2 1 MDM2-binding RsbRD_N PF14361.6 OWF49412.1 - 0.15 12.8 0.9 0.31 11.8 0.1 2.0 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain zf-C2H2 PF00096.26 OWF49414.1 - 1.9e-11 43.8 30.7 0.00035 20.9 0.2 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF49414.1 - 6.4e-10 39.0 29.1 0.012 16.4 0.1 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF49414.1 - 2.4e-09 37.2 23.2 0.14 12.6 0.2 6.0 5 1 0 5 5 5 4 Zinc-finger double domain C1_4 PF07975.12 OWF49414.1 - 0.0051 17.0 17.9 0.012 15.9 0.2 4.2 3 1 1 4 4 4 1 TFIIH C1-like domain zf-C2H2_6 PF13912.6 OWF49414.1 - 0.035 14.1 24.8 0.89 9.6 0.3 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF49414.1 - 0.045 14.1 0.2 0.045 14.1 0.2 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.16 OWF49414.1 - 0.057 13.7 13.3 0.53 10.6 0.8 3.4 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-met PF12874.7 OWF49414.1 - 0.17 12.3 0.0 0.17 12.3 0.0 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 OWF49414.1 - 0.45 10.3 13.8 0.76 9.6 1.0 4.0 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 OWF49414.1 - 4.5 7.7 14.6 3.6 8.0 0.1 3.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 OWF49414.1 - 6.6 7.3 8.4 3 8.4 0.7 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 OWF49415.1 - 3.3e-11 43.0 22.2 4.7e-05 23.6 0.7 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF49415.1 - 1.3e-07 31.8 23.7 0.0023 18.6 0.5 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF49415.1 - 8.6e-07 28.8 10.7 0.056 13.5 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF49415.1 - 4e-05 23.9 18.5 0.017 15.5 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF49415.1 - 0.00011 22.4 13.3 0.66 10.3 2.4 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 OWF49415.1 - 0.015 16.0 5.3 0.015 16.0 5.3 1.8 2 0 0 2 2 2 0 zinc-ribbon family zf-met PF12874.7 OWF49415.1 - 0.015 15.6 11.5 0.18 12.2 1.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OWF49415.1 - 0.16 11.8 0.3 0.16 11.8 0.3 3.0 3 1 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OWF49415.1 - 0.29 11.1 9.4 9.6 6.2 0.0 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF629 PF04780.12 OWF49415.1 - 8.9 4.7 9.8 1.5 7.3 4.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) SSF PF00474.17 OWF49416.1 - 1.4e-05 24.2 2.8 1.9e-05 23.7 2.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 OWF49417.1 - 2.7e-30 105.6 13.7 4.6e-30 104.8 13.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3149 PF11346.8 OWF49417.1 - 1.3 8.7 6.5 7.3 6.3 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) Methyltransf_11 PF08241.12 OWF49418.1 - 3e-10 40.6 0.0 9.1e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF49418.1 - 3.5e-09 37.3 0.0 6.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF49418.1 - 5.1e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF49418.1 - 0.00036 21.2 0.0 0.0006 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF49418.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short PF00106.25 OWF49419.1 - 3.8e-44 150.5 0.1 5.2e-44 150.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF49419.1 - 3.4e-27 95.5 0.0 4.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF49419.1 - 7e-08 32.6 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF49419.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Vac14_Fab1_bd PF12755.7 OWF49420.1 - 1.7e-15 57.4 2.6 0.0029 18.2 0.0 7.1 6 1 2 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 OWF49420.1 - 6.4e-15 55.3 0.3 2.3e-05 24.7 0.0 6.1 5 2 2 7 7 7 5 HEAT repeats HEAT PF02985.22 OWF49420.1 - 1.1e-14 53.2 11.5 0.28 11.5 0.0 10.0 12 0 0 12 12 10 4 HEAT repeat HEAT_EZ PF13513.6 OWF49420.1 - 6.8e-13 48.8 0.8 0.087 13.4 0.1 8.8 9 1 1 10 10 10 2 HEAT-like repeat Cnd1 PF12717.7 OWF49420.1 - 1.6e-10 41.3 9.8 0.0004 20.5 0.0 6.2 5 2 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OWF49420.1 - 3.1e-09 36.7 1.0 0.086 12.4 0.0 5.1 3 1 2 5 5 5 4 CLASP N terminal Nipped-B_C PF12830.7 OWF49420.1 - 0.0088 16.0 0.5 2.8 7.8 0.0 4.0 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Dopey_N PF04118.14 OWF49420.1 - 0.014 14.5 0.9 1 8.4 0.4 3.5 3 0 0 3 3 3 0 Dopey, N-terminal Xpo1 PF08389.12 OWF49420.1 - 0.015 15.3 0.7 3.5 7.7 0.0 4.1 3 1 0 3 3 3 0 Exportin 1-like protein MMS19_N PF14500.6 OWF49420.1 - 0.021 14.4 4.0 0.1 12.2 0.6 3.5 6 0 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.7 OWF49420.1 - 0.042 14.2 0.4 0.15 12.3 0.4 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion RPAP3_C PF13877.6 OWF49420.1 - 0.063 13.8 0.4 0.52 10.9 0.1 2.6 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 UNC45-central PF11701.8 OWF49420.1 - 0.69 9.9 4.9 27 4.7 0.1 4.0 3 2 0 3 3 3 0 Myosin-binding striated muscle assembly central VWA_3 PF13768.6 OWF49422.1 - 2.3e-46 157.6 0.0 4e-20 72.3 0.0 3.7 3 1 0 3 3 3 3 von Willebrand factor type A domain VWA PF00092.28 OWF49422.1 - 7.4e-20 71.9 0.0 3.8e-11 43.6 0.0 3.7 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF49422.1 - 2.4e-14 53.9 0.0 4.3e-06 27.3 0.0 3.9 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF49422.1 - 0.0011 18.4 0.2 0.11 11.9 0.0 3.2 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein DUF3787 PF12655.7 OWF49422.1 - 0.1 12.5 0.1 4.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) ATP11 PF06644.11 OWF49422.1 - 1.6 8.5 5.2 0.16 11.8 0.4 1.7 2 0 0 2 2 2 0 ATP11 protein Arf PF00025.21 OWF49423.1 - 3.8e-49 166.5 0.0 4.8e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF49423.1 - 1.7e-08 34.1 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OWF49423.1 - 2.9e-07 30.0 0.0 0.00024 20.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF49423.1 - 4.1e-07 30.1 0.0 6.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OWF49423.1 - 5.8e-07 29.2 0.0 8.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF49423.1 - 7.6e-07 29.4 0.0 1.8e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OWF49423.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF49423.1 - 0.004 16.7 0.1 0.26 10.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OWF49423.1 - 0.037 14.5 0.3 0.047 14.2 0.3 1.6 1 1 0 1 1 1 0 ABC transporter Methyltransf_31 PF13847.6 OWF49424.1 - 1.8e-31 109.0 0.0 2.7e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF49424.1 - 5.2e-22 78.4 0.0 8.7e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF49424.1 - 1.8e-21 76.6 0.0 3.3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF49424.1 - 2.1e-18 66.9 0.0 3.6e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF49424.1 - 2.9e-15 56.5 0.0 3.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF49424.1 - 2.7e-12 46.6 0.0 3.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OWF49424.1 - 2.7e-12 46.5 0.0 4.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OWF49424.1 - 3e-09 36.7 0.1 4.5e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 OWF49424.1 - 1.4e-07 31.1 0.1 2e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 OWF49424.1 - 1.5e-07 31.3 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 OWF49424.1 - 6.3e-07 29.0 0.0 1.9e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_24 PF13578.6 OWF49424.1 - 6.6e-07 30.3 0.1 1.3e-06 29.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OWF49424.1 - 5.2e-05 23.3 0.0 8.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OWF49424.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 OWF49424.1 - 8.6e-05 22.4 0.0 0.0002 21.2 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 OWF49424.1 - 0.00024 21.1 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 OWF49424.1 - 0.0003 20.6 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit UPF0020 PF01170.18 OWF49424.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.19 OWF49424.1 - 0.0052 16.9 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 OWF49424.1 - 0.0078 15.6 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 OWF49424.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_15 PF09445.10 OWF49424.1 - 0.021 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.17 OWF49424.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Spermine_synth PF01564.17 OWF49424.1 - 0.092 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain TPMT PF05724.11 OWF49424.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) tRNA_U5-meth_tr PF05958.11 OWF49424.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cytochrom_B561 PF03188.16 OWF49425.1 - 1.7e-43 148.1 11.1 1.7e-43 148.1 11.1 1.9 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 OWF49425.1 - 0.00046 20.2 8.6 0.015 15.2 0.1 2.9 1 1 2 3 3 3 1 Tight junction protein, Claudin-like CUB PF00431.20 OWF49426.1 - 7.4e-18 64.9 0.2 4.5e-11 43.1 0.1 2.3 2 0 0 2 2 2 2 CUB domain IncD PF17628.2 OWF49427.1 - 0.23 11.2 3.1 34 4.2 0.0 3.6 1 1 2 4 4 4 0 Inclusion membrane protein D Phage_antitermQ PF06530.12 OWF49427.1 - 0.91 9.4 3.8 30 4.5 0.2 3.1 1 1 3 4 4 4 0 Phage antitermination protein Q DUF2656 PF10847.8 OWF49427.1 - 2.5 8.2 3.4 27 4.9 0.1 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2656) Bactofilin PF04519.13 OWF49428.1 - 0.00046 20.4 15.9 4.5e+02 1.2 15.9 4.7 1 1 0 1 1 1 0 Polymer-forming cytoskeletal SCP2 PF02036.17 OWF49428.1 - 0.00074 20.0 0.0 24 5.5 0.0 4.1 1 1 1 3 3 3 2 SCP-2 sterol transfer family Phage_antitermQ PF06530.12 OWF49428.1 - 0.055 13.4 6.7 7 6.6 0.2 3.7 1 1 2 4 4 4 0 Phage antitermination protein Q Baculo_PEP_C PF04513.12 OWF49428.1 - 0.11 12.5 5.2 1.8 8.6 0.9 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YbjQ_1 PF01906.17 OWF49428.1 - 0.12 13.0 22.3 1.5 9.5 2.1 3.3 1 1 3 4 4 4 0 Putative heavy-metal-binding DUF3672 PF12421.8 OWF49428.1 - 0.64 9.9 10.5 10 6.1 2.3 3.3 1 1 2 3 3 3 0 Fibronectin type III protein Apolipoprotein PF01442.18 OWF49429.1 - 0.0001 22.3 5.4 0.061 13.2 1.2 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mucin-like PF16058.5 OWF49429.1 - 0.0074 16.3 21.0 0.075 13.1 8.6 2.2 1 1 1 2 2 2 2 Mucin-like TryThrA_C PF12319.8 OWF49429.1 - 0.036 13.5 21.4 0.15 11.6 7.8 2.3 1 1 1 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal GrpE PF01025.19 OWF49429.1 - 1.8 8.2 15.9 2.5 7.7 3.0 3.1 1 1 1 2 2 2 0 GrpE Apolipoprotein PF01442.18 OWF49430.1 - 6.7e-26 91.3 50.6 0.00071 19.5 3.4 7.6 1 1 7 8 8 8 8 Apolipoprotein A1/A4/E domain TryThrA_C PF12319.8 OWF49430.1 - 1.4e-12 47.5 148.2 0.14 11.6 34.4 10.8 1 1 9 10 10 10 10 Tryptophan-Threonine-rich plasmodium antigen C terminal Mucin-like PF16058.5 OWF49430.1 - 0.00014 21.9 135.4 4.7 7.4 10.3 9.3 1 1 2 5 5 5 5 Mucin-like An_peroxidase PF03098.15 OWF49431.1 - 2.2e-163 544.6 0.0 3.3e-163 544.1 0.0 1.3 1 0 0 1 1 1 1 Animal haem peroxidase DUF2158 PF09926.9 OWF49431.1 - 0.2 11.4 0.0 0.54 10.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) An_peroxidase PF03098.15 OWF49432.1 - 1e-149 499.5 0.0 1.3e-149 499.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase 7tm_1 PF00001.21 OWF49433.1 - 7e-56 189.5 17.0 8.6e-56 189.2 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49433.1 - 2.9e-13 49.8 14.6 4.4e-13 49.2 14.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 OWF49433.1 - 1.4e-10 41.0 11.8 2.2e-10 40.4 11.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 OWF49433.1 - 1.1e-05 25.2 17.4 1.1e-05 25.2 17.4 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF49433.1 - 0.0044 16.8 8.1 0.0094 15.7 8.1 1.7 1 0 0 1 1 1 1 Olfactory receptor TatD_DNase PF01026.21 OWF49434.1 - 4.5e-14 52.4 0.0 5.8e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Arf PF00025.21 OWF49435.1 - 4.3e-51 172.8 0.0 5e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF49435.1 - 2e-13 50.6 0.0 2.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OWF49435.1 - 3.1e-12 46.3 0.0 4.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OWF49435.1 - 1.6e-11 44.0 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OWF49435.1 - 5.8e-10 38.9 0.1 2.3e-06 27.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF49435.1 - 3.5e-07 30.3 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF49435.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF49435.1 - 0.0014 18.2 0.1 0.018 14.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 OWF49435.1 - 0.003 17.6 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OWF49435.1 - 0.004 17.6 0.0 0.0063 16.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 OWF49435.1 - 0.011 14.7 0.1 3.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DAP3 PF10236.9 OWF49435.1 - 0.022 13.9 0.0 0.065 12.4 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.6 OWF49435.1 - 0.024 14.8 0.1 0.042 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 OWF49435.1 - 0.037 13.9 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 OWF49435.1 - 0.11 12.1 0.3 0.61 9.7 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OWF49435.1 - 0.12 11.4 0.2 0.24 10.4 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 OWF49435.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Tachylectin PF14517.6 OWF49435.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Tachylectin NACHT PF05729.12 OWF49435.1 - 0.17 11.8 0.8 3.3 7.6 0.8 2.1 1 1 0 1 1 1 0 NACHT domain SAP PF02037.27 OWF49436.1 - 1.8e-15 56.3 2.6 2e-15 56.1 0.5 2.3 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 OWF49436.1 - 1.1e-10 41.2 14.1 0.0002 21.1 0.2 4.5 2 2 2 4 4 4 4 Tho1/MOS11 C-terminal domain GP40 PF11025.8 OWF49436.1 - 0.0044 16.8 0.3 0.0044 16.8 0.3 1.6 2 0 0 2 2 2 1 Glycoprotein GP40 of Cryptosporidium SCO1-SenC PF02630.14 OWF49436.1 - 0.019 14.9 0.2 0.044 13.7 0.2 1.6 1 0 0 1 1 1 0 SCO1/SenC DUF4065 PF13274.6 OWF49436.1 - 0.11 13.4 0.3 0.33 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) TubC_N PF18563.1 OWF49436.1 - 0.13 12.3 0.0 0.68 10.0 0.0 2.2 1 0 0 1 1 1 0 TubC N-terminal docking domain Mago-bind PF09282.10 OWF49437.1 - 4.7e-16 58.3 2.0 7.7e-16 57.7 2.0 1.4 1 0 0 1 1 1 1 Mago binding T4SS PF07996.11 OWF49438.1 - 0.06 13.7 7.6 0.068 13.6 6.9 1.4 1 1 0 1 1 1 0 Type IV secretion system proteins SNN_linker PF09050.10 OWF49438.1 - 0.089 12.6 0.4 0.22 11.3 0.4 1.7 1 0 0 1 1 1 0 Stannin unstructured linker CCDC-167 PF15188.6 OWF49438.1 - 0.25 11.7 13.6 0.8 10.1 5.5 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Phage_int_SAM_6 PF18644.1 OWF49438.1 - 0.63 10.1 3.5 0.79 9.8 1.3 2.1 2 0 0 2 2 2 0 Phage integrase SAM-like domain SLX9 PF15341.6 OWF49438.1 - 0.83 10.0 21.1 0.79 10.1 14.3 2.0 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 DUF573 PF04504.14 OWF49438.1 - 0.89 10.3 7.9 2.3 8.9 8.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF573 PCRF PF03462.18 OWF49438.1 - 2.4 8.0 9.0 1.7 8.5 7.6 1.4 1 1 0 1 1 1 0 PCRF domain zf-B_box PF00643.24 OWF49439.1 - 1.7e-07 31.2 7.9 3.9e-07 30.1 7.9 1.6 1 0 0 1 1 1 1 B-box zinc finger DUF4347 PF14252.6 OWF49439.1 - 0.054 13.4 1.0 0.13 12.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) HMw1_D2 PF18254.1 OWF49439.1 - 0.14 12.5 0.8 12 6.4 0.0 3.2 3 1 0 3 3 3 0 HMW1 domain 2 Prot_inhib_II PF02428.15 OWF49439.1 - 1.4 9.4 7.3 3.3 8.2 7.3 1.6 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family HU-CCDC81_bac_2 PF18175.1 OWF49439.1 - 1.6 8.7 6.3 3.9 7.4 0.4 3.0 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 FAT PF02259.23 OWF49440.1 - 2.5e-66 224.3 6.2 7.3e-66 222.7 6.2 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OWF49440.1 - 2.4e-17 63.6 0.1 1.1e-16 61.4 0.1 2.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OWF49440.1 - 1.3e-05 24.8 0.0 4.4e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 FATC domain ACDC PF14733.6 OWF49440.1 - 0.0044 17.3 0.8 0.054 13.8 0.1 3.4 2 0 0 2 2 2 1 AP2-coincident C-terminal IFRD PF05004.13 OWF49440.1 - 0.01 15.0 7.1 0.017 14.3 0.1 4.1 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) TPR_2 PF07719.17 OWF49440.1 - 0.061 13.5 3.1 2.7 8.3 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 OWF49440.1 - 0.14 12.5 0.0 1.9e+02 2.7 0.0 4.7 3 0 0 3 3 3 0 HEAT repeat TPR_16 PF13432.6 OWF49440.1 - 0.24 12.1 2.0 26 5.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 OWF49440.1 - 0.24 11.1 2.6 0.52 10.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain MMS19_N PF14500.6 OWF49440.1 - 0.32 10.5 12.6 5.1 6.6 0.5 5.5 5 1 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 OWF49440.1 - 0.38 10.3 10.5 0.64 9.5 0.2 4.9 5 0 0 5 5 5 0 CLASP N terminal Ras PF00071.22 OWF49441.1 - 3.1e-38 130.9 0.1 4.1e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF49441.1 - 5.9e-23 81.4 0.0 1.2e-22 80.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF49441.1 - 1.9e-05 24.2 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF49441.1 - 7.8e-05 22.6 0.0 0.22 11.4 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF49441.1 - 9.9e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF49441.1 - 0.00031 20.2 0.1 0.0005 19.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OWF49441.1 - 0.00065 19.3 0.1 0.0018 17.8 0.1 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 OWF49441.1 - 0.0043 17.3 0.3 0.0099 16.1 0.1 1.7 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 OWF49441.1 - 0.0043 17.1 0.1 0.0078 16.2 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 OWF49441.1 - 0.0076 15.1 0.0 0.0091 14.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) TniB PF05621.11 OWF49441.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 OWF49441.1 - 0.049 13.4 0.2 0.11 12.2 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 OWF49441.1 - 0.064 12.8 0.3 0.52 9.9 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 OWF49441.1 - 0.094 13.2 0.1 0.27 11.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 OWF49441.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea zf-C3HC4 PF00097.25 OWF49442.1 - 8.9e-07 28.7 5.9 8.9e-07 28.7 5.9 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF49442.1 - 1.5e-06 28.1 7.8 1.5e-06 28.1 7.8 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 OWF49442.1 - 3.6e-05 23.8 5.4 3.6e-05 23.8 5.4 3.7 3 0 0 3 3 3 2 B-box zinc finger zf-RING_5 PF14634.6 OWF49442.1 - 0.0001 22.2 8.2 0.0001 22.2 8.2 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF49442.1 - 0.00015 21.6 4.9 0.00015 21.6 4.9 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF49442.1 - 0.00044 20.5 8.1 0.00044 20.5 8.1 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF49442.1 - 0.0022 18.1 9.8 0.0022 18.1 9.8 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Exonuc_VII_L PF02601.15 OWF49442.1 - 0.94 9.0 6.0 1.5 8.4 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DSPc PF00782.20 OWF49443.1 - 4.6e-32 110.6 0.0 6.3e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF49443.1 - 5.5e-05 22.8 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RA PF00788.23 OWF49444.1 - 1.2e-07 32.2 0.1 3.3e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 OWF49444.1 - 2.4e-07 31.2 0.3 6.1e-07 29.9 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF49444.1 - 0.025 15.0 0.2 0.16 12.4 0.3 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SWIRM-assoc_1 PF16495.5 OWF49444.1 - 0.33 11.0 4.5 0.57 10.2 2.6 2.2 2 0 0 2 2 2 0 SWIRM-associated region 1 MCCD1 PF15707.5 OWF49444.1 - 6.4 7.3 7.9 4.5 7.8 0.6 3.5 4 0 0 4 4 4 0 Mitochondrial coiled-coil domain protein 1 Cullin PF00888.22 OWF49445.1 - 2.4e-169 564.9 7.2 3.1e-169 564.5 7.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OWF49445.1 - 1.2e-26 92.5 2.8 1.2e-26 92.5 2.8 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain TPR_1 PF00515.28 OWF49446.1 - 1.8e-41 138.3 6.8 8.6e-07 28.5 0.2 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 OWF49446.1 - 5.4e-35 116.7 4.6 1.6e-05 24.7 0.3 9.5 8 1 1 9 9 9 8 Tetratricopeptide repeat RPAP3_C PF13877.6 OWF49446.1 - 4.4e-21 75.2 0.3 1.9e-20 73.2 0.0 2.3 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 OWF49446.1 - 1.1e-17 62.7 8.1 3.2e-05 23.8 0.1 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 OWF49446.1 - 1.2e-15 57.4 0.2 1.6e-05 24.9 0.2 5.2 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF49446.1 - 2.2e-14 52.9 3.2 0.11 12.3 0.3 8.0 5 3 4 9 9 9 4 TPR repeat TPR_12 PF13424.6 OWF49446.1 - 1.2e-12 47.9 6.7 0.09 13.1 0.1 7.0 5 2 1 6 6 6 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF49446.1 - 2.6e-09 37.0 5.7 0.028 14.5 0.5 4.5 3 1 1 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 OWF49446.1 - 8.8e-08 32.3 1.6 0.26 12.2 0.4 6.6 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF49446.1 - 7.6e-07 28.7 7.2 13 6.1 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF49446.1 - 2.2e-06 28.1 5.5 0.61 10.6 0.0 5.9 3 3 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF49446.1 - 2.8e-05 24.2 8.5 9.1 6.9 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF49446.1 - 0.00021 21.7 7.2 0.33 11.7 0.4 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 OWF49446.1 - 0.0014 17.9 5.2 3.6 6.7 0.1 4.8 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF49446.1 - 0.0083 16.0 5.9 5.7 7.0 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 OWF49446.1 - 0.015 15.4 16.0 5 7.3 0.1 6.3 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 OWF49446.1 - 0.016 15.8 11.0 0.52 11.0 0.6 4.9 4 3 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF49446.1 - 0.024 14.9 8.1 0.74 10.1 0.3 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OWF49446.1 - 0.045 14.2 4.7 11 6.4 0.0 4.6 4 1 0 4 4 4 0 Bacterial transcriptional activator domain DUF5638 PF18688.1 OWF49446.1 - 0.075 13.3 1.0 0.43 10.9 1.0 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5638) ATP-grasp_3 PF02655.14 OWF49447.1 - 0.013 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.16 OWF49448.1 - 1.5e-44 152.4 47.5 7.9e-27 94.1 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF49448.1 - 3.9e-06 26.0 26.1 0.0034 16.3 5.7 3.6 2 2 1 3 3 3 3 MFS_1 like family Mob1_phocein PF03637.17 OWF49449.1 - 4.9e-34 117.8 0.8 6.8e-34 117.3 0.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family LRAT PF04970.13 OWF49450.1 - 1.9e-07 31.4 0.5 0.0031 17.8 0.1 2.1 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF49450.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 NlpC/P60 family 7tm_1 PF00001.21 OWF49451.1 - 3.2e-43 147.9 18.1 4e-43 147.6 18.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF49451.1 - 9.6e-07 28.8 11.0 2.7e-06 27.3 11.1 1.7 1 1 0 1 1 1 1 Olfactory receptor Pkinase PF00069.25 OWF49453.1 - 1.1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49453.1 - 8.8e-09 35.0 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PTS_EIIB PF00367.20 OWF49454.1 - 0.0001 21.7 4.8 55 3.4 0.0 9.1 11 0 0 11 11 11 0 phosphotransferase system, EIIB Phage_Treg PF04761.12 OWF49454.1 - 0.46 10.6 26.2 14 5.9 0.6 6.6 1 1 6 7 7 7 0 Lactococcus bacteriophage putative transcription regulator Cytomega_UL84 PF06284.11 OWF49454.1 - 0.48 8.8 7.4 2 6.8 0.7 3.2 1 1 2 3 3 3 0 Cytomegalovirus UL84 protein AKAP95 PF04988.12 OWF49454.1 - 2 8.6 8.8 20 5.4 0.3 3.5 1 1 4 5 5 5 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.25 OWF49455.1 - 6e-23 81.5 0.1 9.8e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49455.1 - 3.4e-18 65.9 0.2 5.1e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4559 PF15112.6 OWF49456.1 - 3.1e-14 53.4 3.1 3.7e-14 53.1 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) Glyco_hydro_3 PF00933.21 OWF49457.1 - 1.6e-44 152.6 0.0 6.3e-44 150.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OWF49457.1 - 1.4e-41 142.7 0.0 2.1e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OWF49457.1 - 2.3e-07 30.8 0.4 1.1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain CARDB PF07705.11 OWF49457.1 - 0.021 15.1 0.1 0.046 14.0 0.1 1.5 1 0 0 1 1 1 0 CARDB EF-hand_1 PF00036.32 OWF49458.1 - 2.1e-23 80.1 3.7 8.1e-07 28.2 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF49458.1 - 7.2e-22 77.6 3.1 1.6e-14 54.1 0.5 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF49458.1 - 7.3e-19 66.0 2.2 3.1e-05 23.6 0.0 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF49458.1 - 3.9e-16 57.7 3.0 3.5e-05 23.1 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OWF49458.1 - 1.2e-13 50.6 6.7 0.00013 21.7 0.2 3.7 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF49458.1 - 7.2e-07 29.5 0.8 6e-05 23.3 0.8 3.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF49458.1 - 4.8e-05 23.3 0.8 0.54 10.2 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OWF49458.1 - 0.025 14.8 0.7 2.5 8.3 0.0 2.7 2 1 1 3 3 3 0 Dockerin type I domain MecA_N PF05223.11 OWF49458.1 - 0.086 13.1 0.9 4.4 7.6 0.3 2.9 2 1 1 3 3 3 0 NTF2-like N-terminal transpeptidase domain ANF_receptor PF01094.28 OWF49459.1 - 8.9e-41 140.2 0.7 1.4e-37 129.6 0.7 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 OWF49459.1 - 3.3e-38 130.9 0.0 7.1e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF49459.1 - 1.6e-30 105.7 0.0 5.6e-30 103.9 0.0 1.9 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF49459.1 - 9.6e-24 84.1 0.0 3.2e-23 82.3 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 OWF49459.1 - 2.5e-16 59.4 0.9 5.2e-16 58.4 0.9 1.6 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.6 OWF49459.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Ion_trans_2 PF07885.16 OWF49459.1 - 0.025 14.6 1.5 0.1 12.6 0.8 2.4 2 0 0 2 2 2 0 Ion channel Csa1 PF06023.12 OWF49459.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 bZIP_Maf PF03131.17 OWF49460.1 - 4.8e-30 103.9 7.4 6.4e-30 103.5 7.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 OWF49460.1 - 1.5e-07 31.4 8.5 5.3e-07 29.7 8.9 1.7 2 0 0 2 2 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF49460.1 - 8.5e-05 22.6 12.8 0.0001 22.3 10.7 2.1 1 1 1 2 2 2 1 Basic region leucine zipper FapA PF03961.13 OWF49460.1 - 0.00047 18.9 0.5 0.00053 18.7 0.5 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A JIP_LZII PF16471.5 OWF49460.1 - 0.03 14.5 0.5 0.03 14.5 0.5 2.3 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 OWF49460.1 - 0.036 13.8 1.0 0.036 13.8 1.0 2.2 1 1 1 2 2 2 0 Septum formation initiator KASH_CCD PF14662.6 OWF49460.1 - 0.041 13.7 5.9 0.12 12.2 4.2 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF5384 PF17358.2 OWF49460.1 - 0.072 13.1 5.8 0.18 11.9 5.9 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5384) DUF1825 PF08855.10 OWF49460.1 - 0.11 12.4 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) ZapB PF06005.12 OWF49460.1 - 0.14 12.6 6.3 0.16 12.4 0.1 2.5 1 1 1 2 2 2 0 Cell division protein ZapB CorA PF01544.18 OWF49460.1 - 0.18 11.1 0.9 0.22 10.8 0.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 OWF49460.1 - 0.23 11.5 3.6 0.32 11.1 3.5 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1192 PF06698.11 OWF49460.1 - 0.3 11.2 2.4 5.1 7.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Myb_DNA-bind_3 PF12776.7 OWF49460.1 - 0.45 11.5 1.8 4.2 8.4 1.1 2.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HALZ PF02183.18 OWF49460.1 - 0.5 10.6 9.5 0.57 10.5 3.3 2.9 2 1 2 4 4 4 0 Homeobox associated leucine zipper DUF5364 PF17322.2 OWF49460.1 - 1.8 8.9 9.4 0.88 9.9 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5364) Oxidored-like PF09791.9 OWF49462.1 - 1.1e-13 50.6 3.9 1.9e-13 49.8 3.9 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal POC3_POC4 PF10448.9 OWF49462.1 - 0.048 13.7 0.0 0.068 13.2 0.0 1.1 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 DUF982 PF06169.12 OWF49462.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Linker_histone PF00538.19 OWF49464.1 - 5.1e-17 62.0 0.2 5.1e-17 62.0 0.2 3.0 2 1 0 2 2 2 1 linker histone H1 and H5 family DUF3263 PF11662.8 OWF49464.1 - 0.44 10.4 2.1 22 5.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3263) MscS_TM PF12794.7 OWF49464.1 - 0.62 8.9 3.3 0.91 8.3 3.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2052 PF09747.9 OWF49464.1 - 0.76 9.9 8.9 0.98 9.5 8.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Dicty_REP PF05086.12 OWF49464.1 - 1.9 6.3 15.7 2.2 6.2 15.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GAGA_bind PF06217.12 OWF49464.1 - 2.6 8.3 18.7 3.4 7.9 18.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Membralin PF09746.9 OWF49464.1 - 8.4 5.3 10.3 10 5.0 10.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF4464 PF14713.6 OWF49465.1 - 2.7e-06 27.1 4.6 27 4.2 0.0 8.1 2 2 8 11 11 11 6 Domain of unknown function (DUF4464) DUF3433 PF11915.8 OWF49467.1 - 2.3e-08 34.4 9.1 0.029 14.8 0.1 5.0 1 1 4 5 5 5 4 Protein of unknown function (DUF3433) DUF5476 PF17570.2 OWF49467.1 - 3.1 8.3 19.8 52 4.3 0.4 6.0 4 2 0 6 6 6 0 Family of unknown function (DUF5476) LRR_8 PF13855.6 OWF49469.1 - 5.1e-54 179.9 40.0 1.3e-13 50.5 5.1 9.1 3 3 7 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 OWF49469.1 - 3.7e-26 90.8 41.1 2.7e-05 24.4 0.1 9.9 4 2 5 11 11 11 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF49469.1 - 2.5e-17 63.0 0.0 0.00067 19.6 0.0 4.7 4 1 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF49469.1 - 1.6e-08 33.9 34.5 0.11 13.1 0.0 11.9 14 1 1 15 15 15 3 Leucine Rich Repeat LRR_9 PF14580.6 OWF49469.1 - 1.6e-07 31.0 8.7 0.21 11.1 1.3 4.4 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 OWF49469.1 - 1.7e-05 24.4 27.8 0.5 10.6 0.1 10.5 11 0 0 11 11 11 2 Leucine Rich repeat fn3 PF00041.21 OWF49469.1 - 0.00053 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRRNT PF01462.18 OWF49469.1 - 0.012 15.3 2.9 0.012 15.3 2.9 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain RasGEF PF00617.19 OWF49470.1 - 7.3e-19 68.6 0.2 1.5e-18 67.7 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OWF49470.1 - 3.7e-13 49.6 0.5 1.2e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif KIND PF16474.5 OWF49470.1 - 1.6e-10 41.3 0.2 0.00077 19.4 0.0 3.5 3 0 0 3 3 3 2 Kinase non-catalytic C-lobe domain Pkinase PF00069.25 OWF49470.1 - 0.037 13.4 0.0 0.91 8.8 0.0 2.7 1 1 0 1 1 1 0 Protein kinase domain Aminotran_1_2 PF00155.21 OWF49471.1 - 8.7e-84 281.8 0.0 9.9e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Mab-21 PF03281.14 OWF49472.1 - 1e-36 126.7 0.4 1.3e-36 126.4 0.4 1.1 1 0 0 1 1 1 1 Mab-21 protein Galanin PF01296.18 OWF49473.1 - 0.00042 20.3 4.0 12 6.0 0.0 4.9 4 0 0 4 4 4 3 Galanin FtsK_4TM PF13491.6 OWF49473.1 - 0.034 13.9 0.4 30 4.3 0.1 3.0 2 1 1 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE DUF1232 PF06803.12 OWF49473.1 - 2.8 7.8 15.0 20 5.1 0.0 6.2 7 0 0 7 7 7 0 Protein of unknown function (DUF1232) HLH PF00010.26 OWF49474.1 - 2.3e-10 40.2 0.1 5.4e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain KASH_CCD PF14662.6 OWF49474.1 - 0.022 14.6 1.4 0.022 14.6 1.4 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GTA_TIM PF13547.6 OWF49475.1 - 0.11 11.8 0.6 0.17 11.2 0.6 1.2 1 0 0 1 1 1 0 GTA TIM-barrel-like domain Bromodomain PF00439.25 OWF49477.1 - 4.7e-19 68.2 0.2 1.6e-18 66.5 0.2 2.0 1 0 0 1 1 1 1 Bromodomain ATP-synt_ab PF00006.25 OWF49478.1 - 6.1e-67 225.4 0.0 9.2e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OWF49478.1 - 1.3e-12 48.0 0.7 2.4e-12 47.2 0.2 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF5526 PF17664.1 OWF49479.1 - 3.7e-28 98.2 0.8 4.8e-28 97.8 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5526) ATG19_autophagy PF12744.7 OWF49479.1 - 0.0013 17.9 0.2 0.0017 17.6 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding RRM_1 PF00076.22 OWF49480.1 - 3.2e-42 142.2 0.9 1.3e-19 69.7 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_1_7 PF13843.6 OWF49480.1 - 1.9e-06 27.5 0.0 0.0042 16.5 0.0 2.5 2 0 0 2 2 2 2 Transposase IS4 RRM_7 PF16367.5 OWF49480.1 - 0.00017 21.6 0.5 1.1 9.5 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 OWF49480.1 - 0.12 12.4 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Ribosomal_L7Ae PF01248.26 OWF49481.1 - 5.3e-27 93.4 0.1 7e-27 93.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family baeRF_family2 PF18844.1 OWF49481.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 DUF1601 PF07671.11 OWF49481.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DDRGK PF09756.9 OWF49482.1 - 3.2e-59 199.7 32.1 3.2e-59 199.7 32.1 1.4 2 0 0 2 2 2 1 DDRGK domain FeoC PF09012.10 OWF49482.1 - 0.0003 20.8 0.2 0.86 9.7 0.0 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator HTH_DeoR PF08220.12 OWF49482.1 - 0.0014 18.3 0.3 0.082 12.7 0.0 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain PCI PF01399.27 OWF49482.1 - 0.0086 16.6 2.4 0.0093 16.5 0.6 1.9 2 0 0 2 2 2 1 PCI domain DUF3347 PF11827.8 OWF49482.1 - 0.072 13.3 12.6 0.14 12.4 12.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) FAM60A PF15396.6 OWF49482.1 - 0.23 11.5 8.4 0.41 10.6 8.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A AAA_11 PF13086.6 OWF49482.1 - 0.6 9.8 8.9 0.77 9.5 8.9 1.3 1 0 0 1 1 1 0 AAA domain DUF5401 PF17380.2 OWF49482.1 - 0.75 7.8 24.7 0.87 7.6 24.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) OAD_gamma PF04277.13 OWF49482.1 - 1.4 9.6 0.0 1.4 9.6 0.0 3.0 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Zip PF02535.22 OWF49482.1 - 3.2 6.9 5.1 7.3 5.7 4.9 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter MDM10 PF12519.8 OWF49482.1 - 6.9 5.4 6.8 8.9 5.1 6.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Rhodanese PF00581.20 OWF49483.1 - 3.1e-10 40.5 0.0 5.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 OWF49484.1 - 2e-10 41.1 0.0 3.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain LRR_4 PF12799.7 OWF49485.1 - 9.5e-10 38.6 17.4 0.42 11.1 0.5 8.1 7 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF49485.1 - 1e-05 25.2 22.5 1.4 9.1 0.0 9.8 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 OWF49485.1 - 0.006 17.0 12.2 3.5 8.5 0.1 6.8 6 1 0 6 6 6 2 Leucine Rich Repeat AP-5_subunit_s1 PF15001.6 OWF49486.1 - 7.6e-58 195.7 1.0 8.6e-58 195.5 1.0 1.0 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 PAS_3 PF08447.12 OWF49487.1 - 4.6e-20 71.7 0.2 1.2e-14 54.3 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 OWF49487.1 - 4.4e-18 65.4 0.5 4.4e-14 52.6 0.0 3.5 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 OWF49487.1 - 7.4e-16 58.2 1.2 1.5e-06 28.2 0.0 3.4 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 OWF49487.1 - 5.3e-08 33.1 0.0 0.0019 18.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OWF49487.1 - 0.0021 18.3 0.0 3.1 8.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold 7tm_1 PF00001.21 OWF49488.1 - 6.9e-53 179.6 20.6 6.9e-53 179.6 20.6 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49488.1 - 1.9e-11 43.9 21.0 2.6e-11 43.4 21.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF49488.1 - 0.00016 21.5 15.1 0.00027 20.8 15.1 1.4 1 1 0 1 1 1 1 Olfactory receptor IgGFc_binding PF17517.2 OWF49489.1 - 1.3e-67 228.1 7.2 1.3e-67 228.1 7.2 2.2 2 0 0 2 2 2 1 IgGFc binding protein TSP_1 PF00090.19 OWF49489.1 - 1.2e-35 121.4 59.7 2.6e-11 43.6 7.6 4.7 4 0 0 4 4 4 4 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF49489.1 - 4.1e-05 23.7 13.9 4.1e-05 23.7 13.9 4.3 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A DDE_Tnp_4 PF13359.6 OWF49490.1 - 9.5e-31 106.6 0.0 1.2e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OWF49490.1 - 2.6e-10 40.2 0.0 7.5e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OWF49490.1 - 8.1e-06 25.6 0.0 0.00069 19.3 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OWF49490.1 - 0.0036 17.6 0.1 0.0077 16.6 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE domain Galactosyl_T PF01762.21 OWF49491.1 - 4.2e-39 134.4 0.1 5.8e-39 133.9 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF49491.1 - 0.021 14.3 0.2 0.058 12.8 0.2 1.6 1 1 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 OWF49492.1 - 1.5e-23 83.7 0.0 2.3e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase RXT2_N PF08595.11 OWF49493.1 - 0.4 10.7 2.7 0.39 10.7 0.2 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Mei5 PF10376.9 OWF49494.1 - 5.3e-21 75.4 8.7 5.3e-21 75.4 8.7 2.7 2 1 1 3 3 3 1 Double-strand recombination repair protein Mei5_like PF17021.5 OWF49494.1 - 9.9e-06 25.6 0.5 2.1e-05 24.6 0.5 1.5 1 0 0 1 1 1 1 Putative double-strand recombination repair-like Borrelia_lipo_1 PF05714.11 OWF49494.1 - 0.023 14.5 2.7 0.04 13.7 2.7 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein NBP1 PF08537.10 OWF49494.1 - 1.5 8.1 15.4 0.11 11.9 3.7 3.0 3 1 0 3 3 3 0 Fungal Nap binding protein NBP1 adh_short PF00106.25 OWF49495.1 - 1e-27 96.9 0.0 1.4e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF49495.1 - 2.3e-23 83.0 0.0 1.5e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF49495.1 - 3.1e-06 27.2 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OWF49495.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OWF49495.1 - 0.071 13.0 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding COPIIcoated_ERV PF07970.12 OWF49496.1 - 4.7e-35 121.4 0.1 9.7e-35 120.4 0.1 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OWF49496.1 - 8.6e-31 106.1 0.1 8.6e-31 106.1 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Galactosyl_T PF01762.21 OWF49498.1 - 9.9e-39 133.2 0.6 1.3e-38 132.7 0.6 1.2 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 OWF49499.1 - 3.1e-41 141.4 0.3 4.5e-41 140.8 0.3 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF49499.1 - 0.0016 18.0 2.4 0.002 17.6 0.3 2.2 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OWF49500.1 - 7.3e-42 143.4 0.2 1e-41 142.9 0.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF49500.1 - 0.001 18.6 2.3 0.0014 18.1 0.3 2.2 2 1 0 2 2 2 1 Fringe-like Glycos_transf_2 PF00535.26 OWF49500.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Transglut_core PF01841.19 OWF49501.1 - 2e-13 50.8 0.1 1.5e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase-like superfamily Retinal PF15449.6 OWF49501.1 - 5.7 4.6 6.5 0.23 9.2 0.3 1.5 1 1 1 2 2 2 0 Retinal protein DUF2043 PF09740.9 OWF49502.1 - 4e-34 117.5 0.0 1.8e-33 115.4 0.0 2.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) Enolase_C PF00113.22 OWF49503.1 - 2.2e-38 132.2 0.0 4.1e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OWF49503.1 - 4.2e-12 46.4 5.7 3.9e-09 36.8 0.1 3.6 4 0 0 4 4 4 2 Enolase, N-terminal domain 2OG-FeII_Oxy PF03171.20 OWF49504.1 - 3e-15 56.5 0.0 5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OWF49504.1 - 2e-14 54.4 0.0 2.9e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal zf-C2H2_4 PF13894.6 OWF49505.1 - 3.4e-20 71.0 44.2 0.00073 20.2 4.9 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF49505.1 - 2e-19 68.9 49.2 6.5e-05 23.2 5.7 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF49505.1 - 1.4e-10 41.2 41.2 0.001 19.3 0.2 7.5 6 2 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF49505.1 - 2.2e-10 40.5 52.1 0.00023 21.5 1.3 8.1 8 1 0 8 8 8 5 Zinc-finger double domain zf-C2HC_2 PF13913.6 OWF49505.1 - 1.2e-05 25.0 24.9 0.029 14.3 0.1 6.2 6 0 0 6 6 6 3 zinc-finger of a C2HC-type zf-met PF12874.7 OWF49505.1 - 6e-05 23.3 23.6 1.2 9.7 1.2 6.6 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 OWF49505.1 - 0.00017 21.1 28.1 0.43 10.2 0.1 6.2 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OWF49505.1 - 0.0029 17.7 30.4 0.2 11.8 4.8 5.6 3 2 4 7 7 7 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 OWF49505.1 - 0.0037 17.0 0.2 0.0037 17.0 0.2 5.6 7 0 0 7 7 7 2 zinc-finger C2H2-type zf_Hakai PF18408.1 OWF49505.1 - 0.013 15.2 0.2 0.013 15.2 0.2 3.4 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain Zn_ribbon_SprT PF17283.2 OWF49505.1 - 0.017 15.0 3.1 0.017 15.0 3.1 4.5 2 2 2 4 4 4 0 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 OWF49505.1 - 0.036 14.8 26.6 0.1 13.4 3.3 3.8 1 1 3 5 5 5 0 zinc-ribbon family zf-C2H2_8 PF15909.5 OWF49505.1 - 0.04 14.2 23.3 0.14 12.5 7.6 3.8 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 OWF49505.1 - 0.12 12.0 0.3 0.12 12.0 0.3 4.6 3 1 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 OWF49505.1 - 0.13 12.2 18.1 7 6.6 0.8 5.7 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger ARS2 PF04959.13 OWF49505.1 - 0.24 11.7 8.6 0.77 10.1 3.6 3.0 1 1 0 2 2 2 0 Arsenite-resistance protein 2 XPA_N PF01286.18 OWF49505.1 - 0.26 11.4 23.2 1.6 8.8 0.2 6.1 6 0 0 6 6 6 0 XPA protein N-terminal Spt46 PF17734.1 OWF49505.1 - 0.42 10.4 16.8 0.089 12.6 3.4 3.0 1 1 1 3 3 3 0 Spermatogenesis-associated protein 46 C1_4 PF07975.12 OWF49505.1 - 1.4 9.2 32.9 7 7.0 4.8 5.5 1 1 5 6 6 6 0 TFIIH C1-like domain DUF3268 PF11672.8 OWF49505.1 - 3.2 8.1 17.2 8.3 6.8 2.3 3.4 2 1 0 3 3 3 0 zinc-finger-containing domain zf-C2HE PF16278.5 OWF49505.1 - 3.6 8.1 43.9 0.49 10.9 2.1 6.4 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-FCS PF06467.14 OWF49505.1 - 4.5 7.3 26.2 4.4 7.3 0.4 6.2 6 1 1 7 7 6 0 MYM-type Zinc finger with FCS sequence motif Evr1_Alr PF04777.13 OWF49505.1 - 6.5 7.3 25.9 2.9 8.4 1.3 5.0 1 1 3 4 4 4 0 Erv1 / Alr family 7tm_1 PF00001.21 OWF49506.1 - 5.6e-76 255.3 9.2 8.4e-45 153.1 2.9 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49506.1 - 1.1e-13 51.1 9.0 3.4e-12 46.3 3.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF49506.1 - 7.8e-11 42.1 4.5 7.8e-11 42.1 4.5 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF49506.1 - 8.7e-05 22.0 11.7 0.0046 16.3 0.2 2.9 3 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 OWF49506.1 - 0.00013 21.8 1.7 0.00013 21.8 1.7 2.4 3 0 0 3 3 3 2 Olfactory receptor Syntaxin-18_N PF10496.9 OWF49507.1 - 3.7e-20 72.0 0.4 3.7e-20 72.0 0.4 2.5 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OWF49507.1 - 0.0059 16.6 0.4 0.024 14.6 0.4 2.0 1 0 0 1 1 1 1 SNARE domain DUF5352 PF17303.2 OWF49507.1 - 0.34 10.7 3.1 0.17 11.7 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5352) ALMT PF11744.8 OWF49507.1 - 0.85 8.4 7.9 1.2 7.9 7.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-tcix PF14952.6 OWF49508.1 - 6.9e-23 80.0 5.8 1.6e-22 78.8 5.8 1.7 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.9 OWF49508.1 - 0.096 12.2 2.5 0.25 10.8 2.5 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Glyco_hydro_18 PF00704.28 OWF49509.1 - 8.9e-19 68.3 0.0 1.1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Rad52_Rad22 PF04098.15 OWF49510.1 - 1.6e-08 34.6 0.2 2.5e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 OWF49510.1 - 7.3e-05 22.5 0.2 0.34 10.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 OWF49511.1 - 1.2e-42 145.6 0.1 1.4e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OWF49511.1 - 0.00069 19.5 0.0 0.00091 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF49511.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Lipocalin_2 PF08212.12 OWF49512.1 - 2.8e-16 59.7 0.2 3.5e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF49512.1 - 2e-12 47.5 0.0 2.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 OWF49512.1 - 0.00082 19.0 0.1 0.0011 18.6 0.1 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Triabin PF03973.13 OWF49512.1 - 0.0062 16.4 1.5 0.017 15.0 1.5 1.8 1 1 0 1 1 1 1 Triabin Shisa PF13908.6 OWF49513.1 - 0.0028 17.9 19.7 0.017 15.4 0.7 2.1 1 1 1 2 2 2 2 Wnt and FGF inhibitory regulator Herpes_LAMP2 PF06126.11 OWF49513.1 - 0.3 9.7 4.0 0.36 9.4 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Lipocalin PF00061.23 OWF49514.1 - 2.8e-05 24.3 0.0 5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF49514.1 - 0.0067 16.3 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 1 Triabin Amidase_2 PF01510.25 OWF49515.1 - 6.3e-17 62.2 0.1 8.4e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Amidase_2 PF01510.25 OWF49516.1 - 3.7e-18 66.2 0.1 4.9e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Fibrinogen_BP PF08017.11 OWF49517.1 - 1.3e-13 50.2 81.3 6.8e-07 28.1 33.4 2.2 1 1 1 2 2 2 2 Fibrinogen binding protein Cornifin PF02389.15 OWF49517.1 - 7.1 6.8 23.3 9 6.5 1.7 4.9 1 1 3 5 5 5 0 Cornifin (SPRR) family Homeodomain PF00046.29 OWF49518.1 - 1e-21 76.5 5.2 1.6e-21 75.9 5.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF49518.1 - 0.097 12.6 0.3 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF5409 PF17421.2 OWF49519.1 - 0.9 10.3 4.7 1.6 9.5 0.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5409) TRAP-gamma PF07074.12 OWF49519.1 - 3.2 7.3 4.2 17 4.9 0.4 2.2 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Baculo_PEP_C PF04513.12 OWF49520.1 - 3e-07 30.6 0.0 0.084 12.9 0.0 3.3 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0184 PF03670.13 OWF49520.1 - 0.069 13.6 5.7 1e+02 3.4 0.0 5.3 1 1 6 7 7 7 0 Uncharacterised protein family (UPF0184) Glyco_H_20C_C PF18088.1 OWF49520.1 - 1.2 8.9 17.2 51 3.6 0.4 7.5 2 2 4 7 7 7 0 Glycoside Hydrolase 20C C-terminal domain L51_S25_CI-B8 PF05047.16 OWF49521.1 - 8.6e-11 41.6 0.3 1.8e-10 40.6 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain 7tm_1 PF00001.21 OWF49522.1 - 4.1e-43 147.6 26.1 6.1e-43 147.0 26.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF49522.1 - 3.2e-09 36.6 25.1 4.6e-09 36.0 25.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF49522.1 - 3.9e-05 23.4 24.2 8.9e-05 22.2 24.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SSF PF00474.17 OWF49523.1 - 4.9e-36 124.5 29.1 6.4e-36 124.1 29.1 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family TraQ PF09679.10 OWF49523.1 - 0.013 15.4 0.3 0.07 13.1 0.3 2.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) CCAP PF11105.8 OWF49524.1 - 4.8e-06 26.6 15.5 0.012 15.6 1.6 4.3 1 1 2 3 3 3 3 Arthropod cardioacceleratory peptide 2a Pkinase PF00069.25 OWF49525.1 - 4.5e-64 216.3 0.0 5.3e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49525.1 - 5.4e-35 120.9 0.0 6.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF49525.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF49525.1 - 0.00059 18.7 0.0 0.0012 17.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase DUF2371 PF10177.9 OWF49526.1 - 0.00052 20.2 2.0 0.19 11.9 0.6 2.6 1 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2371) DUF3899 PF13038.6 OWF49526.1 - 0.021 15.3 0.0 0.42 11.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Ring_hydroxyl_A PF00848.19 OWF49526.1 - 0.042 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) DUF2207 PF09972.9 OWF49526.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RGS PF00615.19 OWF49527.1 - 0.086 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain zf-LYAR PF08790.11 OWF49528.1 - 1.6e-14 53.5 2.5 1.6e-14 53.5 2.5 3.0 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 OWF49528.1 - 0.019 14.5 0.2 9.2 6.0 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CDC27 PF09507.10 OWF49528.1 - 0.027 13.9 39.6 0.042 13.2 39.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ATG16 PF08614.11 OWF49529.1 - 0.0091 16.2 20.1 0.0091 16.2 20.1 4.0 2 2 2 5 5 5 2 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 OWF49529.1 - 0.027 15.0 34.0 0.17 12.4 5.5 5.2 3 1 2 5 5 5 0 Syntaxin 6, N-terminal LPP PF04728.13 OWF49529.1 - 0.035 14.5 1.6 0.035 14.5 1.6 4.3 3 2 2 5 5 5 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 OWF49529.1 - 0.11 12.9 0.4 0.11 12.9 0.4 5.6 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) PilJ PF13675.6 OWF49529.1 - 0.37 10.8 11.6 1.5 8.9 0.7 4.3 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_13 PF13166.6 OWF49529.1 - 1.1 7.9 43.0 0.015 14.0 21.6 2.4 1 1 0 2 2 2 0 AAA domain DUF4407 PF14362.6 OWF49529.1 - 3.7 6.8 29.9 0.07 12.5 1.6 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) HisKA_3 PF07730.13 OWF49529.1 - 5.3 7.6 8.9 5.5 7.6 0.4 4.2 4 0 0 4 4 4 0 Histidine kinase zf-nanos PF05741.13 OWF49530.1 - 6.4e-26 90.3 3.4 1.3e-25 89.4 3.4 1.6 1 0 0 1 1 1 1 Nanos RNA binding domain zf-HIT PF04438.16 OWF49530.1 - 2.9 7.8 12.6 0.22 11.4 2.3 2.9 3 0 0 3 3 3 0 HIT zinc finger PC-Esterase PF13839.6 OWF49532.1 - 2.2e-06 27.7 4.9 4.2e-05 23.4 0.2 3.3 1 1 1 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PC-Esterase PF13839.6 OWF49533.1 - 0.00078 19.3 4.1 0.044 13.5 0.5 3.0 1 1 1 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Shufflon_N PF04917.12 OWF49533.1 - 0.1 12.0 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region LMF1 PF06762.14 OWF49534.1 - 1.6e-114 383.5 16.4 5.1e-69 233.5 1.6 2.6 1 1 1 2 2 2 2 Lipase maturation factor SUB1_ProdP9 PF18213.1 OWF49535.1 - 0.024 14.5 0.0 0.086 12.7 0.0 1.9 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF4127 PF13552.6 OWF49535.1 - 0.14 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Peptidase_C36 PF05415.11 OWF49535.1 - 0.27 11.4 1.7 25 5.2 0.2 2.4 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase LRR_4 PF12799.7 OWF49535.1 - 0.96 10.0 6.3 4.7 7.8 0.1 4.1 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF49535.1 - 3.2 8.0 6.8 7.7 6.9 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat WD40 PF00400.32 OWF49536.1 - 1.9e-09 37.9 0.6 0.051 14.5 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF49536.1 - 0.00015 22.0 0.0 7.4 6.9 0.0 5.8 3 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OWF49536.1 - 1.2 9.7 6.2 1.6e+02 3.0 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain BcrAD_BadFG PF01869.20 OWF49537.1 - 1.9e-21 76.8 0.2 2.5e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family CC2-LZ PF16516.5 OWF49538.1 - 1.2e-08 35.2 13.8 1.2e-08 35.2 13.8 6.8 2 2 4 7 7 7 3 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator UPF0242 PF06785.11 OWF49538.1 - 0.013 15.6 66.0 0.099 12.7 7.3 4.8 2 1 3 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus EABR PF12180.8 OWF49538.1 - 0.013 15.1 4.8 0.013 15.1 4.8 2.2 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 Spc7 PF08317.11 OWF49538.1 - 0.041 12.7 67.0 0.0097 14.8 6.3 4.3 2 1 2 4 4 4 0 Spc7 kinetochore protein GAS PF13851.6 OWF49538.1 - 0.048 13.0 65.5 0.06 12.7 4.7 5.0 2 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding DUF4250 PF14056.6 OWF49538.1 - 0.17 11.9 1.3 27 4.8 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Pkinase PF00069.25 OWF49539.1 - 4.7e-28 98.3 0.1 6.1e-28 97.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49539.1 - 1.5e-15 57.2 0.0 1.8e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF49539.1 - 7.7e-11 41.4 0.1 1e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF49539.1 - 0.042 13.2 0.1 0.078 12.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF49539.1 - 0.054 12.8 0.0 1.1 8.6 0.0 2.2 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 OWF49539.1 - 0.18 11.7 0.0 0.47 10.3 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lectin_C PF00059.21 OWF49540.1 - 8.4e-06 26.5 1.8 8.4e-06 26.5 1.8 2.5 2 0 0 2 2 2 1 Lectin C-type domain PAN_4 PF14295.6 OWF49540.1 - 0.0019 18.1 0.3 0.0053 16.6 0.3 1.7 1 0 0 1 1 1 1 PAN domain Per1 PF04080.13 OWF49540.1 - 0.0071 16.1 0.3 0.015 15.1 0.3 1.5 1 0 0 1 1 1 1 Per1-like family PAN_2 PF08276.11 OWF49540.1 - 0.045 13.9 2.1 0.096 12.8 0.2 2.5 3 0 0 3 3 3 0 PAN-like domain Tic110 PF16940.5 OWF49540.1 - 2.1 6.7 4.5 3.1 6.2 4.5 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Cu-oxidase_3 PF07732.15 OWF49541.1 - 2.8e-18 66.0 4.5 6.4e-06 26.2 0.1 5.2 4 1 0 4 4 4 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF49541.1 - 0.0028 17.4 5.6 4.9 6.9 0.5 4.8 5 1 0 5 5 5 2 Multicopper oxidase adh_short PF00106.25 OWF49544.1 - 6.5e-35 120.4 0.0 4.2e-34 117.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF49544.1 - 1.8e-24 86.6 0.0 1.4e-23 83.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF49544.1 - 1.8e-07 31.2 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF49544.1 - 5.1e-06 26.1 0.0 7.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OWF49544.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Cytochrome-c551 PF10643.9 OWF49544.1 - 0.87 9.1 4.6 4.1 6.9 4.6 2.0 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Shisa PF13908.6 OWF49545.1 - 0.013 15.8 8.1 0.018 15.3 8.1 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 OWF49545.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 CYYR1 PF10873.8 OWF49545.1 - 0.087 13.3 32.6 0.56 10.6 32.6 1.9 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 OWF49545.1 - 0.46 11.4 3.4 0.74 10.7 3.4 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OWF49545.1 - 7.5 6.5 5.3 12 5.9 5.3 1.3 1 0 0 1 1 1 0 Syndecan domain CYYR1 PF10873.8 OWF49546.1 - 0.0021 18.5 20.8 0.0032 17.9 20.8 1.4 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Comm PF15957.5 OWF49547.1 - 0.051 13.9 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Commissureless Minor_capsid_1 PF10665.9 OWF49547.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein Zn_peptidase_2 PF04298.12 OWF49547.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DAG1 PF05454.11 OWF49547.1 - 0.61 9.4 7.3 3.3 7.0 1.4 2.1 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) BTB_2 PF02214.22 OWF49548.1 - 6.7e-18 64.8 0.4 2.2e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DUSP PF06337.12 OWF49548.1 - 8.8e-08 32.7 1.2 3.2e-06 27.7 0.5 2.9 2 1 0 2 2 2 1 DUSP domain Ubiquitin_3 PF14836.6 OWF49548.1 - 0.00029 20.8 0.1 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain PNKP_ligase PF16542.5 OWF49548.1 - 0.024 14.2 0.9 0.037 13.5 0.9 1.2 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain HopW1-1 PF15457.6 OWF49548.1 - 0.043 13.1 1.0 0.066 12.5 1.0 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA BTB_3 PF16017.5 OWF49548.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF4407 PF14362.6 OWF49548.1 - 0.63 9.3 4.8 1 8.6 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OWF49548.1 - 1.1 8.7 4.9 1.6 8.2 4.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TIR_2 PF13676.6 OWF49549.1 - 0.0005 20.7 0.0 0.00099 19.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF49549.1 - 0.00071 19.4 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF49550.1 - 1.6e-16 59.8 22.0 0.0011 18.6 1.7 7.8 6 2 0 7 7 7 6 Leucine rich repeat TIR_2 PF13676.6 OWF49550.1 - 6.9e-14 52.5 0.1 2.8e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 OWF49550.1 - 9.7e-13 48.3 0.1 1.8e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF49550.1 - 2.1e-08 34.3 19.6 0.17 12.4 2.3 9.2 5 3 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF49550.1 - 0.0084 16.1 18.3 8.2 6.8 0.0 8.6 10 0 0 10 10 10 1 Leucine Rich repeat Gal_Lectin PF02140.18 OWF49551.1 - 1.7e-45 153.3 18.6 1.8e-24 85.9 6.6 2.1 2 0 0 2 2 2 2 Galactose binding lectin domain PBP3 PF18056.1 OWF49551.1 - 0.029 14.5 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain DUF3395 PF11875.8 OWF49551.1 - 0.041 13.8 0.4 10 6.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3395) fn3_6 PF17766.1 OWF49551.1 - 0.041 14.1 0.4 11 6.3 0.1 2.2 2 0 0 2 2 2 0 Fibronectin type-III domain TUG-UBL1 PF11470.8 OWF49551.1 - 0.044 14.0 0.1 38 4.6 0.0 3.1 3 0 0 3 3 3 0 TUG ubiquitin-like domain Ldl_recept_a PF00057.18 OWF49551.1 - 0.18 12.1 10.8 18 5.7 0.6 4.2 4 1 1 5 5 5 0 Low-density lipoprotein receptor domain class A CPW_WPC PF09717.10 OWF49551.1 - 4 8.5 15.4 1.8 9.6 0.6 3.4 1 1 2 3 3 3 0 Plasmodium falciparum domain of unknown function (CPW_WPC) T-box PF00907.22 OWF49552.1 - 1.2e-75 253.8 0.1 1.8e-75 253.2 0.1 1.3 1 0 0 1 1 1 1 T-box HCV_capsid PF01543.17 OWF49552.1 - 0.034 14.3 0.1 0.092 12.9 0.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus capsid protein 7tm_1 PF00001.21 OWF49553.1 - 3.2e-31 108.6 5.2 4.9e-31 108.0 5.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF49553.1 - 0.00068 19.5 12.5 0.00075 19.3 9.7 2.3 2 1 0 2 2 2 1 Olfactory receptor Fuseless PF15993.5 OWF49553.1 - 0.14 11.3 12.0 0.32 10.2 12.0 1.5 1 0 0 1 1 1 0 Fuseless DUF2207 PF09972.9 OWF49553.1 - 0.36 9.6 13.4 2.5 6.7 0.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2706 PF10913.8 OWF49553.1 - 3.7 7.5 7.7 1.6 8.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2706) DUF4448 PF14610.6 OWF49553.1 - 4.4 7.1 8.0 3 7.6 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4448) 7tm_1 PF00001.21 OWF49554.1 - 1e-31 110.2 0.0 1.6e-31 109.6 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4448 PF14610.6 OWF49554.1 - 0.28 10.9 0.8 17 5.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) DASH_Spc19 PF08287.11 OWF49555.1 - 0.12 12.2 0.2 0.17 11.7 0.2 1.1 1 0 0 1 1 1 0 Spc19 FAD_binding_4 PF01565.23 OWF49557.1 - 9.3e-24 83.7 0.1 1.9e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OWF49557.1 - 1e-11 44.7 0.2 3.5e-11 43.0 0.2 1.9 1 0 0 1 1 1 1 Berberine and berberine like NfrA_C PF13283.6 OWF49557.1 - 0.21 11.1 1.9 0.63 9.5 1.9 1.8 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Cadherin PF00028.17 OWF49559.1 - 1.2e-21 76.9 22.0 1.5e-05 25.3 0.2 6.8 6 1 0 6 6 6 6 Cadherin domain Cadherin_3 PF16184.5 OWF49559.1 - 0.00048 20.1 9.8 0.34 10.9 0.1 4.7 4 1 1 5 5 5 3 Cadherin-like Big_9 PF17963.1 OWF49559.1 - 0.0029 18.3 92.1 0.45 11.3 12.4 7.0 5 2 1 6 6 6 4 Bacterial Ig domain Cadherin_4 PF17803.1 OWF49559.1 - 0.049 14.3 86.4 0.11 13.1 13.5 7.7 5 2 1 6 6 6 0 Bacterial cadherin-like domain GATA PF00320.27 OWF49560.1 - 2.5e-29 100.6 15.6 3.2e-15 55.4 4.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 OWF49560.1 - 0.00019 20.8 9.0 0.022 14.3 2.6 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 OWF49560.1 - 0.021 15.0 1.6 2.1 8.6 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Prim_Zn_Ribbon PF08273.12 OWF49560.1 - 0.13 12.6 8.5 0.56 10.5 1.1 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.7 OWF49560.1 - 0.24 11.4 2.7 17 5.5 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 OWF49560.1 - 0.26 11.2 1.6 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 OWF49560.1 - 1.1 9.5 5.6 1.5 9.0 0.4 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) A2L_zn_ribbon PF08792.10 OWF49560.1 - 1.9 8.3 5.8 33 4.4 0.0 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain Elf1 PF05129.13 OWF49560.1 - 3 8.0 8.1 7.8 6.6 0.2 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Hydin_ADK PF17213.3 OWF49560.1 - 9.6 6.4 11.6 0.79 10.0 4.2 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Glyco_hydro_35 PF01301.19 OWF49561.1 - 2.9e-107 358.9 0.1 3.7e-107 358.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OWF49561.1 - 9.3e-10 38.4 0.0 2.8e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 OWF49561.1 - 0.00013 21.5 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Astacin PF01400.24 OWF49562.1 - 5.4e-37 127.3 0.1 8.3e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 OWF49562.1 - 1.7e-27 95.9 0.0 8.5e-17 61.5 0.0 2.6 2 0 0 2 2 2 2 CUB domain fn3 PF00041.21 OWF49562.1 - 1.3e-08 35.1 0.0 1.3e-05 25.5 0.0 2.9 2 0 0 2 2 2 2 Fibronectin type III domain CUB_2 PF02408.20 OWF49562.1 - 7.4e-06 25.7 0.1 0.037 13.8 0.0 2.9 2 0 0 2 2 2 2 CUB-like domain Hamartin PF04388.12 OWF49562.1 - 5.5 5.5 7.9 7.4 5.1 7.9 1.1 1 0 0 1 1 1 0 Hamartin protein Ras PF00071.22 OWF49563.1 - 1.7e-31 109.0 0.0 2.9e-31 108.3 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF49563.1 - 2.8e-21 76.0 0.0 4.2e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF49563.1 - 4.9e-11 42.4 0.0 5.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF49563.1 - 3.4e-05 23.5 0.0 0.00025 20.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF49563.1 - 0.0046 17.0 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_FA PF12248.8 OWF49564.1 - 1.4e-13 51.0 0.3 2e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase TatD_DNase PF01026.21 OWF49565.1 - 3.3e-14 52.9 0.0 5.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase PMP22_Claudin PF00822.20 OWF49566.1 - 8.3e-14 51.8 8.8 1.1e-13 51.4 8.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF49566.1 - 7e-10 39.0 13.8 3.5e-09 36.7 13.8 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 OWF49566.1 - 2 8.0 16.9 0.016 14.9 6.1 2.3 1 1 0 2 2 2 0 SUR7/PalI family Polysacc_syn_2C PF08485.10 OWF49567.1 - 0.64 9.8 10.5 5.6 6.7 0.4 3.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein C-terminal VPS11_C PF12451.8 OWF49568.1 - 2.6e-21 75.6 1.3 2.6e-21 75.6 1.3 2.2 2 0 0 2 2 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 OWF49568.1 - 1.4e-15 57.4 19.6 2.8e-13 50.0 6.2 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 OWF49568.1 - 8.9e-05 22.3 9.8 0.00018 21.3 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF49568.1 - 0.00017 21.9 9.5 0.00035 20.8 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3H2C3 PF17122.5 OWF49568.1 - 0.0041 17.1 12.5 0.0096 15.9 12.5 1.7 1 0 0 1 1 1 1 Zinc-finger WD40 PF00400.32 OWF49568.1 - 0.012 16.5 0.0 0.32 11.9 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-rbx1 PF12678.7 OWF49568.1 - 0.042 14.2 8.8 0.14 12.5 8.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Vps8 PF12816.7 OWF49568.1 - 0.13 11.7 2.8 4.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 zf-RING-like PF08746.11 OWF49568.1 - 0.44 10.9 6.6 1.3 9.4 6.6 1.8 1 0 0 1 1 1 0 RING-like domain FAM163 PF15069.6 OWF49568.1 - 0.5 10.8 3.5 1.1 9.6 3.5 1.5 1 0 0 1 1 1 0 FAM163 family zf-RING_5 PF14634.6 OWF49568.1 - 0.6 10.1 9.3 1.4 9.0 9.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF49568.1 - 0.85 9.5 10.3 1.7 8.6 10.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Guanylin PF02058.15 OWF49568.1 - 1.2 9.7 7.3 38 4.8 0.0 3.4 3 0 0 3 3 3 0 Guanylin precursor zf-C3HC4_3 PF13920.6 OWF49568.1 - 1.2 9.0 5.7 2.9 7.8 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 OWF49568.1 - 2 8.9 12.1 0.11 12.9 2.2 3.1 3 1 1 4 4 3 0 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 OWF49568.1 - 2.9 7.6 5.5 5.6 6.7 5.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TPR_11 PF13414.6 OWF49568.1 - 5.2 6.8 6.1 12 5.7 0.0 3.9 5 0 0 5 5 5 0 TPR repeat Methyltransf_12 PF08242.12 OWF49569.1 - 0.003 18.3 0.0 0.006 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF49569.1 - 0.0045 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF49569.1 - 0.036 14.7 0.0 0.094 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L10 PF00466.20 OWF49570.1 - 8.4e-20 70.8 0.1 1.4e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 OWF49570.1 - 1.5e-19 70.3 4.9 1.5e-19 70.3 4.9 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 OWF49570.1 - 5.7e-16 58.3 0.1 1.8e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P CBFD_NFYB_HMF PF00808.23 OWF49572.1 - 3.7e-11 43.2 0.0 7.3e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IFT81_CH PF18383.1 OWF49572.1 - 0.15 12.3 2.4 0.99 9.7 0.5 2.1 1 1 1 2 2 2 0 Intraflagellar transport 81 calponin homology domain EF1_GNE PF00736.19 OWF49573.1 - 2.7e-31 107.6 2.8 2.7e-31 107.6 2.8 2.4 3 0 0 3 3 3 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OWF49573.1 - 1.3e-05 25.5 6.9 1.3e-05 25.5 6.9 3.4 4 0 0 4 4 2 1 Eukaryotic elongation factor 1 beta central acidic region Med9 PF07544.13 OWF49573.1 - 0.0047 17.0 4.1 0.51 10.5 0.0 3.2 3 0 0 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 OWF49573.1 - 0.022 15.1 0.7 0.022 15.1 0.7 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) CCD48 PF15799.5 OWF49573.1 - 0.026 12.9 5.7 0.044 12.1 5.7 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 SepF PF04472.12 OWF49573.1 - 0.026 14.8 0.5 1 9.7 0.0 3.0 3 0 0 3 3 3 0 Cell division protein SepF bZIP_1 PF00170.21 OWF49573.1 - 0.033 14.3 3.2 0.034 14.2 0.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor JIP_LZII PF16471.5 OWF49573.1 - 0.086 13.0 0.6 0.086 13.0 0.6 2.3 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II DUF5473 PF17567.2 OWF49573.1 - 0.4 11.0 2.1 10 6.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5473) NinG PF05766.12 OWF49573.1 - 0.55 10.1 3.8 0.9 9.4 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DUF4407 PF14362.6 OWF49573.1 - 8 5.7 9.3 11 5.3 7.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OWF49573.1 - 8.4 6.2 12.0 0.45 10.3 0.3 3.3 3 0 0 3 3 3 0 Septum formation initiator Pkinase PF00069.25 OWF49574.1 - 7.3e-12 45.2 0.1 1.3e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49574.1 - 3.8e-06 26.4 0.1 6.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF49574.1 - 5.7e-06 25.8 0.1 1.1e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF49574.1 - 0.0026 16.6 0.1 0.0038 16.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OWF49574.1 - 0.027 14.4 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF49574.1 - 0.028 13.4 0.6 0.059 12.3 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 OWF49574.1 - 0.047 13.3 0.2 4.1 6.9 0.0 2.7 2 1 1 3 3 3 0 Choline/ethanolamine kinase Fanconi_A PF03511.14 OWF49574.1 - 0.055 13.4 0.1 1.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Fanconi anaemia group A protein YTH PF04146.15 OWF49575.1 - 4.6e-43 147.0 0.2 1.4e-42 145.5 0.2 1.8 1 1 0 1 1 1 1 YT521-B-like domain TIR_2 PF13676.6 OWF49576.1 - 3.1e-08 34.2 0.0 4.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF49576.1 - 4.8e-06 26.5 0.0 6.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 TIR domain Hexapep PF00132.24 OWF49577.1 - 0.0031 17.2 22.6 0.3 10.9 0.4 7.5 6 2 1 7 7 7 2 Bacterial transferase hexapeptide (six repeats) T4-Gluco-transf PF09198.10 OWF49577.1 - 0.022 14.3 39.6 6 6.6 0.8 11.3 1 1 13 14 14 14 0 Bacteriophage T4 beta-glucosyltransferase Flavi_NS4A PF01350.17 OWF49577.1 - 0.12 12.3 34.7 0.059 13.3 4.2 4.0 1 1 3 4 4 4 0 Flavivirus non-structural protein NS4A DUF2985 PF11204.8 OWF49577.1 - 0.42 10.8 42.1 0.93 9.7 1.3 6.4 1 1 5 7 7 7 0 Protein of unknown function (DUF2985) ComP_DUS PF16732.5 OWF49578.1 - 0.015 16.2 0.0 5.7 7.9 0.0 3.2 1 1 1 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor Homoserine_dh PF00742.19 OWF49578.1 - 0.019 14.9 5.5 0.4 10.6 0.5 3.6 1 1 3 4 4 4 0 Homoserine dehydrogenase rve PF00665.26 OWF49578.1 - 0.051 13.8 0.4 8.4 6.6 0.0 2.6 1 1 1 2 2 2 0 Integrase core domain Flavi_NS4A PF01350.17 OWF49578.1 - 0.073 13.0 15.3 0.042 13.8 3.3 3.2 1 1 3 4 4 4 0 Flavivirus non-structural protein NS4A Hexapep PF00132.24 OWF49578.1 - 0.093 12.5 3.9 7.4 6.5 1.4 4.0 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) DUF2985 PF11204.8 OWF49578.1 - 0.35 11.1 14.0 2.6 8.2 0.6 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2985) Rap1a PF18602.1 OWF49578.1 - 0.36 11.2 7.5 27 5.2 0.1 5.5 2 1 4 6 6 6 0 Rap1a immunity proteins GHMP_kinases_C PF08544.13 OWF49578.1 - 0.61 10.5 4.4 49 4.4 0.0 3.4 2 1 0 2 2 2 0 GHMP kinases C terminal T4-Gluco-transf PF09198.10 OWF49578.1 - 1.1 9.0 17.9 17 5.2 0.2 6.9 1 1 8 9 9 9 0 Bacteriophage T4 beta-glucosyltransferase Pox_A32 PF04665.12 OWF49578.1 - 2.1 7.7 14.1 9.2 5.6 0.9 3.6 1 1 1 3 3 3 0 Poxvirus A32 protein Ycf4 PF02392.16 OWF49578.1 - 2.4 7.7 12.4 0.36 10.4 2.4 2.2 1 1 2 3 3 3 0 Ycf4 DUF3456 PF11938.8 OWF49579.1 - 0.0046 17.5 3.6 0.37 11.3 0.4 2.6 1 1 2 3 3 3 3 TLR4 regulator and MIR-interacting MSAP Cnn_1N PF07989.11 OWF49580.1 - 9e-05 22.6 10.3 0.013 15.6 1.7 2.3 2 0 0 2 2 2 2 Centrosomin N-terminal motif 1 Stanniocalcin PF03298.13 OWF49580.1 - 0.0031 16.9 0.5 0.0067 15.8 0.5 1.5 1 0 0 1 1 1 1 Stanniocalcin family Cep57_CLD_2 PF14197.6 OWF49580.1 - 0.0035 17.4 8.2 0.15 12.2 2.8 2.4 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 PRKG1_interact PF15898.5 OWF49580.1 - 0.0042 18.0 8.5 0.55 11.2 0.5 2.7 2 1 0 2 2 2 2 cGMP-dependent protein kinase interacting domain Csm1_N PF18504.1 OWF49580.1 - 0.0083 16.4 9.9 0.26 11.7 1.2 2.7 2 0 0 2 2 2 2 Csm1 N-terminal domain Plk4_PB2 PF18409.1 OWF49580.1 - 0.018 15.7 2.8 1.4 9.7 0.5 2.2 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 HisKA PF00512.25 OWF49580.1 - 0.029 14.4 1.6 0.5 10.4 0.1 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF5320 PF17253.2 OWF49580.1 - 0.032 15.3 1.8 6.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) ADIP PF11559.8 OWF49580.1 - 0.041 14.0 10.9 0.25 11.4 2.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Hemerythrin PF01814.23 OWF49580.1 - 0.044 14.4 1.6 3.2 8.4 0.7 2.3 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain FlaC_arch PF05377.11 OWF49580.1 - 0.047 14.1 5.3 2.1 8.8 0.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 OWF49580.1 - 0.064 13.5 8.9 1.4 9.2 1.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 OWF49580.1 - 0.083 13.3 9.2 0.95 9.8 1.1 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nup88 PF10168.9 OWF49580.1 - 0.086 10.6 9.7 0.1 10.4 9.7 1.1 1 0 0 1 1 1 0 Nuclear pore component zf-CpG_bind_C PF12269.8 OWF49580.1 - 0.1 12.4 8.8 0.19 11.5 0.8 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF1917 PF08939.10 OWF49580.1 - 0.11 12.4 4.1 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) AIP3 PF03915.13 OWF49580.1 - 0.19 10.8 12.6 0.045 12.8 3.7 2.0 1 1 0 2 2 2 0 Actin interacting protein 3 DUF2746 PF10874.8 OWF49580.1 - 0.2 12.1 1.4 1.6 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) BLOC1_2 PF10046.9 OWF49580.1 - 0.37 11.1 7.7 1.1 9.6 0.7 2.6 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JHY PF15261.6 OWF49580.1 - 0.37 11.5 5.9 0.54 11.0 0.6 2.2 2 0 0 2 2 2 0 Jhy protein COMP PF11598.8 OWF49580.1 - 0.47 11.0 3.2 0.33 11.4 0.5 2.2 2 0 0 2 2 1 0 Cartilage oligomeric matrix protein bZIP_Maf PF03131.17 OWF49580.1 - 0.48 11.0 14.8 3.2 8.3 3.3 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor Orthopox_A5L PF06193.11 OWF49580.1 - 0.56 9.6 3.8 0.19 11.1 0.7 1.7 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like YabA PF06156.13 OWF49580.1 - 0.69 10.6 5.9 4.6 7.9 0.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA FUSC-like PF12805.7 OWF49580.1 - 0.7 8.9 3.5 3.2 6.7 1.2 2.0 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS UPF0242 PF06785.11 OWF49580.1 - 0.78 9.8 11.5 1.1 9.4 2.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2968 PF11180.8 OWF49580.1 - 0.79 9.3 10.5 0.54 9.9 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) APG6_N PF17675.1 OWF49580.1 - 1.1 9.8 15.2 3.4 8.2 2.7 2.1 1 1 0 2 2 2 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 OWF49580.1 - 1.2 7.8 14.6 1 8.1 4.0 2.0 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain bZIP_1 PF00170.21 OWF49580.1 - 1.3 9.2 9.1 6 7.0 1.6 2.6 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 OWF49580.1 - 1.3 8.8 13.0 2.6 7.9 3.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Occludin_ELL PF07303.13 OWF49580.1 - 1.5 9.6 10.8 1.5 9.6 1.9 2.3 2 0 0 2 2 2 0 Occludin homology domain Glyco_transf_18 PF15024.6 OWF49580.1 - 1.7 7.2 7.7 0.4 9.2 0.9 2.0 1 1 1 2 2 2 0 Glycosyltransferase family 18 JIP_LZII PF16471.5 OWF49580.1 - 1.9 8.7 8.4 0.93 9.7 1.1 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II CENP-B_N PF04218.13 OWF49580.1 - 2.3 7.9 7.2 1.8 8.2 0.4 3.2 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain bZIP_2 PF07716.15 OWF49580.1 - 2.8 8.1 14.5 5.8 7.1 4.3 2.7 2 0 0 2 2 2 0 Basic region leucine zipper LMBR1 PF04791.16 OWF49580.1 - 5.5 5.8 10.8 11 4.8 10.8 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Fungal_TACC PF12709.7 OWF49580.1 - 8 7.0 12.3 7.2 7.1 1.4 3.0 2 2 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins HALZ PF02183.18 OWF49580.1 - 8.5 6.7 14.8 5 7.4 0.2 3.6 3 1 1 4 4 3 0 Homeobox associated leucine zipper FapA PF03961.13 OWF49580.1 - 9.9 4.6 10.7 1.2 7.7 2.1 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A Trypsin PF00089.26 OWF49581.1 - 7.8e-63 212.2 0.1 9.8e-63 211.9 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF49581.1 - 4e-10 40.8 0.2 7.4e-10 39.9 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF49581.1 - 0.0048 17.3 0.0 0.0079 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 OWF49582.1 - 2.1e-59 201.0 0.6 3.9e-59 200.1 0.1 1.6 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 OWF49582.1 - 9.5e-09 35.7 0.3 2.7e-08 34.2 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 OWF49582.1 - 0.0025 18.7 0.0 0.0083 17.0 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain RRM_5 PF13893.6 OWF49583.1 - 1.1e-56 189.7 0.3 1.1e-42 144.6 0.1 3.2 2 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OWF49583.1 - 4.1e-30 103.4 0.8 2.1e-06 27.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OWF49583.1 - 9.1e-12 45.0 0.0 1.5e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 OWF49583.1 - 3e-10 39.8 0.1 0.16 11.8 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 OWF49583.1 - 0.00013 21.9 0.0 4.5 7.4 0.0 3.9 4 0 0 4 4 4 2 RNA binding motif RL PF17797.1 OWF49583.1 - 0.00023 21.0 0.1 0.082 12.9 0.0 3.5 3 0 0 3 3 3 1 RL domain Limkain-b1 PF11608.8 OWF49583.1 - 0.00034 20.6 0.1 0.13 12.4 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 DUF4523 PF15023.6 OWF49583.1 - 0.03 14.1 0.2 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) DDE_Tnp_4 PF13359.6 OWF49584.1 - 8.2e-18 64.6 0.1 1.4e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OWF49584.1 - 1.1e-08 35.0 0.2 3.2e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OWF49584.1 - 0.00072 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain partial_CstF PF15861.5 OWF49584.1 - 0.021 14.6 0.4 0.053 13.3 0.4 1.7 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain SAND PF01342.21 OWF49584.1 - 0.12 12.1 0.7 8.2 6.2 0.0 3.0 3 0 0 3 3 3 0 SAND domain Aminotran_3 PF00202.21 OWF49585.1 - 8.2e-75 252.0 0.0 1e-74 251.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SIS PF01380.22 OWF49586.1 - 9.5e-61 203.4 0.0 3e-34 117.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OWF49586.1 - 2.1e-18 66.8 0.0 4.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OWF49586.1 - 6e-14 52.0 0.0 1.7e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OWF49586.1 - 6.4e-06 25.3 0.1 1.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 OWF49586.1 - 0.002 16.9 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 OWF49586.1 - 0.0031 17.6 0.0 0.031 14.3 0.0 2.5 2 0 0 2 2 2 1 SIS domain DUF1871 PF08958.10 OWF49586.1 - 0.051 13.9 0.5 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) UBA_e1_thiolCys PF10585.9 OWF49586.1 - 0.086 12.8 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site DNA_pol_B_palm PF14792.6 OWF49587.1 - 2.9e-34 117.7 0.0 5.3e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 OWF49587.1 - 5.1e-21 74.2 0.0 9.8e-21 73.3 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 OWF49587.1 - 3.3e-20 72.0 0.0 1.2e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 OWF49587.1 - 6.2e-19 68.1 0.5 7.7e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_5 PF14520.6 OWF49587.1 - 1.9e-06 28.3 0.2 4.4e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 OWF49587.1 - 0.001 19.2 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 Pathogenicity locus NTP_transf_2 PF01909.23 OWF49587.1 - 0.0048 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain 5_3_exonuc PF01367.20 OWF49587.1 - 0.02 15.5 0.3 0.057 14.0 0.1 1.8 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 OWF49587.1 - 0.053 13.6 0.0 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 OWF49587.1 - 0.066 13.6 0.4 2.5 8.6 0.0 2.7 2 0 0 2 2 2 0 IMS family HHH motif HHH_3 PF12836.7 OWF49587.1 - 0.074 13.3 0.2 4.1 7.7 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif BAF PF02961.14 OWF49587.1 - 0.077 13.4 0.4 8 7.0 0.0 2.7 2 0 0 2 2 2 0 Barrier to autointegration factor UBX PF00789.20 OWF49588.1 - 2.6e-11 43.5 0.0 4.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain Selenoprotein_S PF06936.11 OWF49588.1 - 0.00098 19.0 2.8 0.00098 19.0 2.8 1.5 1 1 0 1 1 1 1 Selenoprotein S (SelS) S-AdoMet_synt_C PF02773.16 OWF49589.1 - 9.5e-68 226.5 0.4 2.3e-67 225.2 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OWF49589.1 - 2.9e-44 150.1 0.0 6.8e-44 149.0 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OWF49589.1 - 6.4e-44 148.7 1.0 1.3e-43 147.7 0.2 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OWF49589.1 - 0.0076 15.1 1.8 0.13 11.0 0.2 2.1 1 1 1 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) HDPD PF02924.14 OWF49590.1 - 1.2e-26 93.1 51.2 4 7.6 0.1 17.4 1 1 42 43 43 43 43 Bacteriophage lambda head decoration protein D Thg1C PF14413.6 OWF49590.1 - 1.5e-13 50.9 37.6 5.2 7.2 1.0 14.0 1 1 13 15 15 15 14 Thg1 C terminal domain NHR2 PF08788.11 OWF49590.1 - 0.00018 21.2 86.8 59 3.5 0.6 24.0 1 1 46 47 47 47 1 NHR2 domain like Calx-beta PF03160.14 OWF49591.1 - 2.6e-61 204.0 7.2 3.9e-15 55.8 0.0 6.0 6 0 0 6 6 6 5 Calx-beta domain Shisa PF13908.6 OWF49591.1 - 3e-06 27.6 1.1 7.7e-06 26.3 1.1 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF49591.1 - 0.00049 20.9 0.5 0.0013 19.5 0.5 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Miga PF10265.9 OWF49591.1 - 0.0067 15.5 3.7 0.01 14.9 3.7 1.1 1 0 0 1 1 1 1 Mitoguardin TMEM51 PF15345.6 OWF49591.1 - 0.0071 16.2 0.3 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 DUF4381 PF14316.6 OWF49591.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Comm PF15957.5 OWF49591.1 - 0.017 15.5 1.3 0.04 14.3 0.4 2.1 2 0 0 2 2 2 0 Commissureless TMEM100 PF16311.5 OWF49591.1 - 0.022 14.4 1.2 0.058 13.0 1.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 TMEM154 PF15102.6 OWF49591.1 - 0.023 14.6 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family WBP-1 PF11669.8 OWF49591.1 - 0.058 14.0 0.9 0.14 12.8 0.9 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 MAP17 PF15807.5 OWF49591.1 - 0.067 13.4 0.6 0.12 12.6 0.6 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SID-1_RNA_chan PF13965.6 OWF49591.1 - 0.07 11.5 0.8 0.11 10.9 0.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM132D_C PF15706.5 OWF49591.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM52 PF14979.6 OWF49591.1 - 0.085 12.8 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Transmembrane 52 Protocadherin PF08374.11 OWF49591.1 - 0.093 12.7 3.3 0.15 12.0 2.7 1.6 2 0 0 2 2 1 0 Protocadherin LST1 PF05083.13 OWF49591.1 - 0.17 12.2 1.9 0.41 10.9 1.9 1.6 1 0 0 1 1 1 0 LST-1 protein OSTbeta PF15048.6 OWF49591.1 - 0.2 11.8 0.6 0.38 10.9 0.6 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein NusG_II PF07009.11 OWF49591.1 - 0.2 11.9 2.5 0.66 10.2 2.5 1.9 1 0 0 1 1 1 0 NusG domain II Nucleoside_tran PF01733.18 OWF49591.1 - 0.21 10.9 0.4 0.37 10.1 0.4 1.3 1 0 0 1 1 1 0 Nucleoside transporter TMIE PF16038.5 OWF49591.1 - 0.47 10.3 3.6 0.93 9.4 3.6 1.4 1 0 0 1 1 1 0 TMIE protein Neur_chan_memb PF02932.16 OWF49591.1 - 0.91 9.5 3.2 1.6 8.7 3.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.16 OWF49592.1 - 2.3e-34 118.9 32.5 5.1e-29 101.3 14.7 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF49592.1 - 1.5e-30 106.4 15.6 2.8e-20 72.6 6.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Reovirus_cap PF00979.17 OWF49592.1 - 0.19 10.9 0.1 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 TRI12 PF06609.13 OWF49592.1 - 1.6 7.0 12.6 0.048 12.1 5.4 2.0 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) CLZ PF16526.5 OWF49593.1 - 0.00084 19.6 6.8 0.037 14.4 0.7 2.1 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmpH PF03938.14 OWF49593.1 - 0.0016 18.8 5.8 0.0022 18.3 5.8 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) ADIP PF11559.8 OWF49593.1 - 0.0029 17.7 7.0 0.004 17.3 7.0 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 OWF49593.1 - 0.0046 16.3 8.0 0.0058 16.0 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 OWF49593.1 - 0.0058 16.2 4.7 0.0076 15.9 4.7 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 OWF49593.1 - 0.0099 14.8 4.9 0.013 14.4 4.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4407 PF14362.6 OWF49593.1 - 0.01 15.2 4.0 0.014 14.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 OWF49593.1 - 0.011 16.0 11.1 0.017 15.5 11.1 1.1 1 0 0 1 1 1 0 YlqD protein BRE1 PF08647.11 OWF49593.1 - 0.012 15.6 7.3 0.018 15.1 7.3 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4200 PF13863.6 OWF49593.1 - 0.014 15.8 5.0 0.019 15.4 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 OWF49593.1 - 0.017 15.1 6.5 0.025 14.5 6.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 OWF49593.1 - 0.017 15.6 6.5 0.029 14.8 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Uso1_p115_C PF04871.13 OWF49593.1 - 0.018 15.4 4.3 0.026 14.9 4.3 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 OWF49593.1 - 0.018 15.1 8.4 0.025 14.6 8.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.9 OWF49593.1 - 0.019 13.5 5.7 0.024 13.2 5.7 1.0 1 0 0 1 1 1 0 Macoilin family Tropomyosin PF00261.20 OWF49593.1 - 0.023 14.1 0.6 0.031 13.7 0.6 1.1 1 0 0 1 1 1 0 Tropomyosin MscS_porin PF12795.7 OWF49593.1 - 0.028 14.0 12.7 0.037 13.6 12.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Jnk-SapK_ap_N PF09744.9 OWF49593.1 - 0.037 14.3 6.6 0.05 13.8 6.6 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 SKA1 PF07160.12 OWF49593.1 - 0.042 13.7 3.3 0.058 13.2 3.3 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF1640 PF07798.11 OWF49593.1 - 0.048 13.7 4.0 0.07 13.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1204 PF06721.11 OWF49593.1 - 0.05 13.0 0.1 0.066 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DASH_Spc34 PF08657.10 OWF49593.1 - 0.051 13.4 3.7 0.067 13.0 3.7 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 TMF_TATA_bd PF12325.8 OWF49593.1 - 0.057 13.6 5.9 0.081 13.2 5.9 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4349 PF14257.6 OWF49593.1 - 0.074 12.5 2.7 0.12 11.8 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Laminin_II PF06009.12 OWF49593.1 - 0.075 13.0 3.0 0.1 12.6 3.0 1.1 1 0 0 1 1 1 0 Laminin Domain II HIP1_clath_bdg PF16515.5 OWF49593.1 - 0.076 13.6 9.7 0.16 12.6 9.7 1.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 OWF49593.1 - 0.077 13.1 4.4 0.11 12.7 4.4 1.1 1 0 0 1 1 1 0 Tropomyosin like HAUS6_N PF14661.6 OWF49593.1 - 0.085 12.4 1.3 0.11 12.1 1.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Phage_GPO PF05929.11 OWF49593.1 - 0.086 12.5 1.6 0.11 12.1 1.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IFT57 PF10498.9 OWF49593.1 - 0.11 11.5 8.5 0.14 11.1 8.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HOOK PF05622.12 OWF49593.1 - 0.13 10.4 6.3 0.16 10.1 6.3 1.0 1 0 0 1 1 1 0 HOOK protein Gp58 PF07902.11 OWF49593.1 - 0.22 9.8 6.0 0.31 9.3 6.0 1.1 1 0 0 1 1 1 0 gp58-like protein Spectrin PF00435.21 OWF49593.1 - 0.22 12.0 4.1 0.35 11.4 4.1 1.2 1 0 0 1 1 1 0 Spectrin repeat ING PF12998.7 OWF49593.1 - 0.36 11.5 5.1 0.55 10.8 5.1 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Nup88 PF10168.9 OWF49593.1 - 0.37 8.5 6.4 0.47 8.2 6.4 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF3073 PF11273.8 OWF49593.1 - 0.65 10.8 3.4 1.1 10.1 0.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3073) GrpE PF01025.19 OWF49593.1 - 1 9.0 5.1 2 8.0 5.1 1.5 1 1 0 1 1 1 0 GrpE Fib_alpha PF08702.10 OWF49593.1 - 1.2 9.3 8.6 1.9 8.7 8.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 OWF49593.1 - 1.7 8.9 10.1 6.2 7.1 2.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tup_N PF08581.10 OWF49593.1 - 2.5 8.5 9.4 6 7.2 1.1 2.2 1 1 1 2 2 2 0 Tup N-terminal SlyX PF04102.12 OWF49593.1 - 2.7 8.7 9.9 0.51 11.0 3.4 2.1 1 1 1 2 2 2 0 SlyX NPV_P10 PF05531.12 OWF49593.1 - 3.6 8.1 8.3 37 4.9 8.3 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 OWF49593.1 - 3.9 8.2 12.1 33 5.3 12.1 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4298 PF14131.6 OWF49593.1 - 6.1 6.9 11.4 13 5.9 4.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) CPG4 PF15481.6 OWF49594.1 - 0.0025 18.4 29.3 0.12 13.0 2.2 5.8 3 2 2 5 5 5 4 Chondroitin proteoglycan 4 Phage_Gp15 PF06854.11 OWF49594.1 - 0.074 13.0 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage Gp15 protein NRN1 PF15056.6 OWF49594.1 - 0.13 12.3 9.4 3.6 7.8 0.4 4.8 4 1 1 5 5 5 0 Neuritin protein family PDEase_I PF00233.19 OWF49595.1 - 3.8e-84 282.2 2.4 6.6e-84 281.4 2.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS_9 PF13426.7 OWF49595.1 - 2.9e-15 56.4 0.0 9.7e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OWF49595.1 - 3.3e-11 43.2 0.0 1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OWF49595.1 - 1.3e-10 41.4 0.2 3.5e-10 40.0 0.1 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OWF49595.1 - 6.7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OWF49595.1 - 0.0075 16.3 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain DUF3417 PF11897.8 OWF49595.1 - 0.019 15.4 0.4 0.097 13.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) PAS_12 PF18095.1 OWF49595.1 - 0.059 13.0 0.6 0.36 10.5 0.0 2.6 3 0 0 3 3 3 0 UPF0242 C-terminal PAS-like domain START PF01852.19 OWF49596.1 - 4.8e-17 62.1 0.0 4.5e-12 45.8 0.0 2.1 1 1 1 2 2 2 2 START domain EMI PF07546.13 OWF49596.1 - 0.87 10.4 4.3 2.3 9.0 4.3 1.8 1 1 0 1 1 1 0 EMI domain CAAP1 PF15335.6 OWF49597.1 - 1.8e-05 25.2 0.0 4.9 7.8 0.0 3.3 1 1 2 3 3 3 2 Caspase activity and apoptosis inhibitor 1 Bromo_TP PF07524.13 OWF49597.1 - 0.00046 20.1 1.5 0.66 10.0 0.1 3.3 1 1 2 3 3 3 2 Bromodomain associated Sec15 PF04091.12 OWF49597.1 - 0.0013 18.2 0.2 0.6 9.5 0.0 2.8 1 1 2 3 3 3 1 Exocyst complex subunit Sec15-like CelTOS PF18659.1 OWF49597.1 - 0.0027 18.1 2.5 10 6.6 0.1 3.7 2 1 2 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites Transketolase_C PF02780.20 OWF49597.1 - 0.016 15.1 6.0 8.1 6.3 0.3 3.2 1 1 2 3 3 3 0 Transketolase, C-terminal domain SWC7 PF17330.2 OWF49597.1 - 0.027 14.5 2.6 30 4.7 0.1 3.2 1 1 1 3 3 3 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Pox_VLTF3 PF04947.14 OWF49597.1 - 0.031 14.0 0.2 11 5.7 0.1 3.1 1 1 1 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like DUF4473 PF14747.6 OWF49597.1 - 0.032 14.8 0.4 8.3 7.0 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) DUF559 PF04480.12 OWF49597.1 - 0.035 14.0 0.9 4.5 7.2 0.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF559) KBP_C PF12309.8 OWF49597.1 - 0.047 13.2 7.1 48 3.3 6.9 3.3 1 1 0 1 1 1 0 KIF-1 binding protein C terminal Elongin_A PF06881.11 OWF49597.1 - 0.074 13.6 6.4 27 5.3 0.1 5.0 1 1 4 5 5 5 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FliG_N PF14842.6 OWF49597.1 - 0.077 13.6 13.6 7.6 7.1 0.8 3.8 1 1 1 2 2 2 0 FliG N-terminal domain MgtE_N PF03448.17 OWF49597.1 - 0.1 13.2 9.1 0.81 10.3 3.7 2.8 1 1 2 3 3 3 0 MgtE intracellular N domain CaMBD PF02888.16 OWF49597.1 - 0.1 12.8 12.7 40 4.5 1.4 6.2 1 1 1 2 2 2 0 Calmodulin binding domain DUF3734 PF12536.8 OWF49597.1 - 0.22 11.9 10.4 18 5.8 0.3 3.8 1 1 2 3 3 3 0 Patatin phospholipase TetR_C_9 PF14514.6 OWF49597.1 - 0.33 11.1 4.0 3.8 7.6 0.1 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3991 PF13154.6 OWF49597.1 - 0.34 11.3 9.2 1.3e+02 3.0 0.1 6.1 1 1 5 7 7 7 0 Protein of unknown function (DUF3991) Nudix_N PF12535.8 OWF49597.1 - 0.36 10.5 21.0 24 4.6 0.4 7.6 1 1 3 5 5 5 0 Hydrolase of X-linked nucleoside diphosphate N terminal ATC_hydrolase PF14196.6 OWF49597.1 - 1.3 9.7 5.0 17 6.2 2.0 2.7 1 1 1 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase ARGLU PF15346.6 OWF49597.1 - 2.1 8.2 19.4 9.4 6.1 3.1 3.4 1 1 2 3 3 3 0 Arginine and glutamate-rich 1 PNISR PF15996.5 OWF49597.1 - 4.1 7.6 8.9 52 4.0 4.1 3.1 1 1 1 2 2 2 0 Arginine/serine-rich protein PNISR Dicty_spore_N PF04562.12 OWF49598.1 - 1.9 9.2 18.0 32 5.3 18.2 2.2 1 1 0 1 1 1 0 Dictyostelium spore coat protein, N terminus Adeno_shaft PF00608.17 OWF49598.1 - 4.9 7.1 13.4 7.4 6.5 0.4 4.4 1 1 5 6 6 6 0 Adenoviral fibre protein (repeat/shaft region) Shugoshin_N PF07558.11 OWF49599.1 - 4.9e-06 26.3 0.3 1.3 9.0 0.1 3.5 3 0 0 3 3 3 2 Shugoshin N-terminal coiled-coil region CLZ PF16526.5 OWF49599.1 - 0.0017 18.7 2.0 0.0053 17.1 0.5 2.0 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAUS-augmin3 PF14932.6 OWF49599.1 - 0.0038 16.9 3.0 0.0043 16.7 3.0 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 OWF49599.1 - 0.0052 17.0 1.8 0.0058 16.9 1.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 OWF49599.1 - 0.0056 16.8 4.2 0.0071 16.4 4.2 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Reprolysin_4 PF13583.6 OWF49599.1 - 0.0058 16.3 0.4 0.0062 16.2 0.4 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CCDC154 PF15450.6 OWF49599.1 - 0.0075 14.9 0.2 0.0084 14.7 0.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 TMF_TATA_bd PF12325.8 OWF49599.1 - 0.017 15.3 1.1 0.02 15.1 1.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DASH_Spc34 PF08657.10 OWF49599.1 - 0.02 14.7 6.1 0.021 14.6 6.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF1204 PF06721.11 OWF49599.1 - 0.03 13.8 0.1 0.034 13.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Fib_alpha PF08702.10 OWF49599.1 - 0.051 13.8 2.9 0.063 13.5 2.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 OWF49599.1 - 0.057 13.7 3.3 0.1 12.9 3.3 1.5 1 1 0 1 1 1 0 Tup N-terminal HIP1_clath_bdg PF16515.5 OWF49599.1 - 0.081 13.5 2.7 0.097 13.3 2.7 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 OWF49599.1 - 0.26 10.6 1.6 0.28 10.5 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliD_N PF02465.18 OWF49599.1 - 0.91 10.3 7.1 2.3 9.0 7.1 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus BA14K PF07886.11 OWF49600.1 - 1e-06 28.5 41.3 0.028 14.3 2.7 8.1 7 3 1 8 8 8 5 BA14K-like protein DUF4106 PF13388.6 OWF49600.1 - 0.05 12.8 39.5 0.26 10.5 8.4 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF4106) SPASM PF13186.6 OWF49600.1 - 0.4 11.2 5.6 5.1 7.7 0.2 3.1 3 1 0 3 3 3 0 Iron-sulfur cluster-binding domain DUF3645 PF12359.8 OWF49600.1 - 3.2 7.2 5.1 12 5.4 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3645) DUF4744 PF15918.5 OWF49601.1 - 3.7e-06 27.7 8.4 0.0036 18.1 1.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4744) DUF4244 PF14029.6 OWF49601.1 - 0.11 12.0 23.0 2.6 7.5 1.4 5.4 1 1 4 5 5 5 0 Protein of unknown function (DUF4244) DUF4744 PF15918.5 OWF49602.1 - 1.3e-05 25.9 29.4 0.0083 16.9 0.9 4.2 1 1 3 4 4 4 4 Domain of unknown function (DUF4744) CAT PF00302.18 OWF49602.1 - 1.3 8.9 4.2 4.6 7.1 0.2 2.8 1 1 1 3 3 3 0 Chloramphenicol acetyltransferase CelTOS PF18659.1 OWF49603.1 - 0.044 14.2 17.9 1.1 9.7 6.6 3.0 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites DsrH PF04077.12 OWF49604.1 - 0.11 12.6 8.2 0.1 12.8 1.2 2.9 1 1 2 3 3 3 0 DsrH like protein UPF0113_N PF17833.1 OWF49604.1 - 0.18 12.4 1.5 4.3 8.0 0.9 2.4 1 1 1 2 2 2 0 UPF0113 Pre-PUA domain betaPIX_CC PF16523.5 OWF49604.1 - 2.9 7.8 7.4 1.1 9.2 3.4 2.2 1 1 1 2 2 2 0 betaPIX coiled coil RHH_6 PF16762.5 OWF49604.1 - 7.5 7.2 8.9 3 8.5 1.0 2.6 1 1 2 3 3 3 0 Ribbon-helix-helix domain DUF1918 PF08940.11 OWF49605.1 - 0.061 13.0 0.8 0.21 11.2 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1918) PTCB-BRCT PF12738.7 OWF49606.1 - 0.037 14.0 0.1 41 4.2 0.0 3.4 2 2 2 4 4 4 0 twin BRCT domain zf-C5HC2 PF02928.16 OWF49606.1 - 4.5 7.7 10.0 18 5.8 4.3 2.7 1 1 1 2 2 2 0 C5HC2 zinc finger Guanylate_cyc PF00211.20 OWF49608.1 - 5.2e-69 231.5 0.1 8e-69 230.9 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OWF49608.1 - 1.2e-45 155.7 14.5 2.3e-44 151.4 9.0 2.5 2 1 0 2 2 2 1 Heme NO binding associated NPCC PF08058.11 OWF49608.1 - 0.07 13.2 1.6 0.12 12.4 0.7 1.8 1 1 1 2 2 2 0 Nuclear pore complex component Glyco_hydro_20 PF00728.22 OWF49609.1 - 1.5e-95 320.6 0.0 2.2e-95 320.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 OWF49609.1 - 2.1e-24 86.0 0.0 4.5e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 OWF49609.1 - 4.7e-21 74.6 0.2 8.5e-20 70.5 0.2 2.4 1 1 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 OWF49609.1 - 6.6e-10 39.8 0.0 1.4e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 BNR PF02012.20 OWF49609.1 - 4.3 7.8 9.1 0.19 11.9 1.9 2.8 3 0 0 3 3 3 0 BNR/Asp-box repeat DUF808 PF05661.12 OWF49610.1 - 0.1 11.6 0.2 0.11 11.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF808) LapA_dom PF06305.11 OWF49610.1 - 1.3 8.9 8.2 4.8 7.1 8.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UPF0542 PF15086.6 OWF49610.1 - 6.7 6.7 11.9 20 5.2 11.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 SNAPc19 PF15497.6 OWF49611.1 - 7.3e-15 55.2 15.0 2.1e-14 53.7 15.0 1.7 1 1 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Glyco_hydro_20 PF00728.22 OWF49612.1 - 1.6e-88 297.5 0.0 2.5e-88 296.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 OWF49612.1 - 8.6e-27 93.8 0.1 2e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 OWF49612.1 - 6.9e-21 74.0 0.0 2.2e-20 72.4 0.0 2.0 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 OWF49612.1 - 1.5e-10 41.9 2.3 2.8e-10 41.1 0.1 2.7 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 BNR PF02012.20 OWF49612.1 - 0.12 12.4 0.2 0.51 10.5 0.2 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat adh_short_C2 PF13561.6 OWF49613.1 - 1.2e-63 214.8 0.0 1.3e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF49613.1 - 4.3e-54 183.0 0.2 5.2e-54 182.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF49613.1 - 5.7e-16 58.9 0.1 7.2e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF49613.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OWF49613.1 - 0.0032 16.7 0.1 0.0052 16.0 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 OWF49613.1 - 0.0063 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) IMS_C PF11799.8 OWF49613.1 - 0.086 13.5 0.0 0.77 10.5 0.0 2.1 2 1 0 2 2 2 0 impB/mucB/samB family C-terminal domain Pacifastin_I PF05375.13 OWF49614.1 - 0.033 13.9 4.5 0.095 12.4 4.5 1.8 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) PSP94 PF05825.11 OWF49614.1 - 0.068 13.7 3.0 0.15 12.6 3.0 1.5 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) EF-hand_1 PF00036.32 OWF49616.1 - 0.0032 16.9 0.0 0.0071 15.8 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OWF49616.1 - 0.022 14.7 0.1 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 OWF49616.1 - 0.063 13.7 0.1 0.1 13.1 0.1 1.5 1 1 0 1 1 1 0 EF-hand domain pair zf-C2H2 PF00096.26 OWF49618.1 - 2.1e-32 109.7 103.0 2.1e-05 24.7 1.2 12.7 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF49618.1 - 3.1e-20 71.1 105.6 0.0011 19.6 1.0 12.9 13 0 0 13 13 13 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF49618.1 - 3.4e-09 36.7 71.2 0.02 15.2 1.9 11.7 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF49618.1 - 8.5e-06 26.0 102.5 0.0034 17.7 2.4 14.1 16 2 0 16 16 16 8 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 OWF49618.1 - 0.016 14.9 25.3 0.58 9.9 0.1 9.0 7 1 2 9 9 9 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 OWF49618.1 - 0.017 15.4 62.0 0.67 10.3 8.9 10.6 4 1 7 11 11 11 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OWF49618.1 - 0.039 13.9 0.0 0.039 13.9 0.0 11.2 11 0 0 11 11 11 0 C2H2-type zinc finger DUF4428 PF14471.6 OWF49618.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) Trm112p PF03966.16 OWF49618.1 - 0.52 10.9 9.2 2.7 8.6 0.7 4.3 4 1 0 4 4 4 0 Trm112p-like protein 7tm_1 PF00001.21 OWF49619.1 - 1.2e-20 74.0 24.2 1.4e-20 73.8 24.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF49619.1 - 3.9e-08 33.2 27.5 3.9e-08 33.2 27.5 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF49619.1 - 1.1e-05 24.9 8.8 1.1e-05 24.9 8.8 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF49620.1 - 1.6e-21 76.9 25.6 1.9e-21 76.6 25.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF49620.1 - 1.1e-07 31.7 32.7 2.4e-07 30.7 30.6 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF49620.1 - 5.1e-07 29.3 27.3 0.00021 20.7 27.3 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF49620.1 - 8.5e-06 25.3 26.7 1.2e-05 24.9 26.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF969 PF06149.12 OWF49620.1 - 0.023 14.1 0.5 0.054 12.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF969) Fibrinogen_C PF00147.18 OWF49621.1 - 1.6e-55 188.3 7.2 2.4e-55 187.8 7.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF49621.1 - 0.0023 17.8 1.9 0.0042 17.0 1.9 1.5 1 0 0 1 1 1 1 PAN domain IL17R_fnIII_D2 PF16578.5 OWF49621.1 - 0.061 13.8 1.6 0.21 12.2 0.1 2.4 2 0 0 2 2 2 0 Interleukin 17 receptor D Aminotran_5 PF00266.19 OWF49622.1 - 3.3e-60 204.0 0.0 3.7e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V EF-hand_7 PF13499.6 OWF49623.1 - 1.3e-08 35.2 0.0 8.3e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF49623.1 - 9.9e-06 25.1 0.4 0.007 16.2 0.0 4.1 3 2 1 4 4 4 1 EF-hand domain DUF1456 PF07308.13 OWF49623.1 - 0.0011 19.2 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) EF-hand_1 PF00036.32 OWF49623.1 - 0.0016 17.9 0.1 0.62 9.8 0.0 3.9 4 0 0 4 4 4 1 EF hand Big_8 PF17961.1 OWF49623.1 - 0.0078 16.3 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial Ig domain DUF4368 PF14287.6 OWF49623.1 - 0.018 15.3 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) DUF3666 PF12408.8 OWF49623.1 - 0.039 13.2 1.3 0.26 10.5 0.4 2.3 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase DUF5580 PF17743.1 OWF49623.1 - 0.048 12.2 0.0 0.049 12.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Mito_carr PF00153.27 OWF49624.1 - 2.7e-68 225.9 0.9 7.1e-22 77.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF49624.1 - 0.0017 17.5 2.5 1.7 7.7 0.0 3.5 1 1 2 4 4 4 2 Gammaproteobacterial serine protease Formyl_trans_N PF00551.19 OWF49625.1 - 3.1e-28 98.7 0.0 1.2e-27 96.9 0.0 2.0 2 1 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 OWF49625.1 - 2.8e-10 40.3 0.0 6.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Ras PF00071.22 OWF49626.1 - 5.7e-59 198.3 0.3 6.8e-59 198.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF49626.1 - 1.3e-35 122.2 0.1 2e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF49626.1 - 1e-14 54.4 0.1 1.2e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF49626.1 - 1.9e-06 27.9 0.2 4.7e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF49626.1 - 0.00015 21.7 0.9 0.025 14.5 0.2 2.3 1 1 1 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OWF49626.1 - 0.00026 20.4 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OWF49626.1 - 0.00049 19.6 0.1 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OWF49626.1 - 0.00092 19.6 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF49626.1 - 0.0029 17.9 0.1 0.014 15.7 0.1 2.0 1 1 1 2 2 2 1 AAA domain DLIC PF05783.11 OWF49626.1 - 0.0039 16.1 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 OWF49626.1 - 0.0075 15.8 0.2 0.022 14.3 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF4623 PF15416.6 OWF49626.1 - 0.009 14.6 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4623) TniB PF05621.11 OWF49626.1 - 0.011 15.2 0.0 0.044 13.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein DNA_pol_E_B PF04042.16 OWF49626.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_5 PF07728.14 OWF49626.1 - 0.022 14.7 0.1 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OWF49626.1 - 0.024 15.2 0.3 0.031 14.8 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OWF49626.1 - 0.028 13.9 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 OWF49626.1 - 0.041 13.4 0.2 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 OWF49626.1 - 0.041 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 OWF49626.1 - 0.043 13.5 0.1 0.13 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OWF49626.1 - 0.056 13.0 0.2 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OWF49626.1 - 0.067 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 OWF49626.1 - 0.08 13.5 0.1 0.26 11.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OWF49626.1 - 0.088 12.8 0.2 0.22 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain PglL_A PF15864.5 OWF49628.1 - 9.1e-05 22.1 4.9 1.5e+02 2.2 0.0 7.9 2 1 6 8 8 8 7 Protein glycosylation ligase Tetraspanin PF00335.20 OWF49629.1 - 1e-22 81.0 7.8 1.4e-22 80.6 7.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Wzy_C PF04932.15 OWF49629.1 - 0.0075 15.9 0.5 0.0075 15.9 0.5 1.8 3 0 0 3 3 3 1 O-Antigen ligase Stevor PF17410.2 OWF49629.1 - 0.62 9.6 2.5 15 5.0 0.0 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame PsaM PF07465.13 OWF49629.1 - 0.71 9.6 7.6 0.069 12.9 1.8 2.2 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) DUF2897 PF11446.8 OWF49629.1 - 2.9 7.9 6.6 2.9 7.9 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) LRR_6 PF13516.6 OWF49630.1 - 8.6e-15 53.5 34.8 0.062 13.4 0.0 10.8 11 0 0 11 11 11 7 Leucine Rich repeat LRR_1 PF00560.33 OWF49630.1 - 3.4 8.6 15.8 68 4.6 0.0 8.8 13 0 0 13 13 13 0 Leucine Rich Repeat LRR_4 PF12799.7 OWF49630.1 - 3.8 8.1 47.5 4.9 7.7 0.8 9.5 7 3 3 10 10 10 0 Leucine Rich repeats (2 copies) YqaJ PF09588.10 OWF49631.1 - 0.00021 21.4 0.0 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain CSF-1 PF05337.11 OWF49631.1 - 0.00094 19.3 1.6 0.28 11.3 0.4 2.9 3 0 0 3 3 3 2 Macrophage colony stimulating factor-1 (CSF-1) Peptidase_C48 PF02902.19 OWF49635.1 - 0.024 14.5 0.1 3.5 7.4 0.1 2.3 1 1 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain Phage_int_SAM_4 PF13495.6 OWF49635.1 - 0.04 14.4 0.1 0.078 13.5 0.1 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain KH_1 PF00013.29 OWF49636.1 - 1.2e-17 63.5 8.6 1.3e-05 24.9 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OWF49636.1 - 2.6e-08 33.6 19.2 0.0094 15.8 0.1 4.6 3 3 1 4 4 4 3 KH domain KH_5 PF13184.6 OWF49636.1 - 0.00063 19.8 12.0 0.21 11.7 0.9 4.1 2 1 2 4 4 4 2 NusA-like KH domain DASH_Dad4 PF08650.10 OWF49636.1 - 0.081 12.9 1.1 0.45 10.5 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad4 WXG100 PF06013.12 OWF49636.1 - 0.12 12.6 0.6 49 4.3 0.0 3.3 4 0 0 4 4 4 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.9 OWF49636.1 - 0.2 11.7 6.2 1.4 8.9 0.1 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 OWF49636.1 - 0.31 11.2 2.7 2.3 8.4 0.4 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Img2 PF05046.14 OWF49636.1 - 0.63 10.4 7.4 0.41 11.0 2.4 2.9 1 1 3 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) MIF4G_like_2 PF09090.11 OWF49636.1 - 1.5 8.2 6.4 1.1 8.7 1.5 2.5 1 1 1 2 2 2 0 MIF4G like Fez1 PF06818.15 OWF49636.1 - 1.6 9.1 6.1 1.9 8.9 3.0 2.2 1 1 1 2 2 2 0 Fez1 NPV_P10 PF05531.12 OWF49636.1 - 4.1 7.9 8.6 14 6.3 0.5 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 OWF49636.1 - 4.2 7.6 8.6 3.6 7.8 5.9 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family JAKMIP_CC3 PF16034.5 OWF49636.1 - 6.5 6.7 7.8 5.8 6.8 5.8 2.0 2 1 0 2 2 2 0 JAKMIP CC3 domain zf-C2H2 PF00096.26 OWF49637.1 - 2.7e-15 55.9 23.8 1.3e-06 28.5 0.8 4.8 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF49637.1 - 1.4e-12 47.4 6.9 1.6e-07 31.4 1.0 4.8 5 1 0 5 5 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF49637.1 - 2.7e-09 37.1 25.9 0.00018 22.1 1.4 4.8 3 1 1 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF49637.1 - 0.019 15.0 15.9 0.079 13.0 1.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF49637.1 - 0.021 15.1 3.4 0.021 15.1 3.4 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon DUF3797 PF12677.7 OWF49637.1 - 0.58 10.1 4.4 5.8 6.9 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-C2H2_jaz PF12171.8 OWF49637.1 - 0.71 10.2 7.6 7.2 7.0 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 OWF49637.1 - 2.1 9.0 11.0 0.97 10.1 0.1 3.2 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 OWF49637.1 - 2.9 7.8 5.6 1.8 8.5 0.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) TFIIA PF03153.13 OWF49637.1 - 2.9 7.8 12.1 6.5 6.6 12.1 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_aberr PF17017.5 OWF49637.1 - 7.3 6.7 7.3 7.4 6.7 0.7 2.6 2 1 0 2 2 2 0 Aberrant zinc-finger PAX PF00292.18 OWF49638.1 - 1.8e-71 237.9 0.5 3e-71 237.2 0.5 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 OWF49638.1 - 9.6e-05 22.1 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 OWF49638.1 - 0.00083 19.9 0.1 0.46 11.1 0.0 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 OWF49638.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain VWA PF00092.28 OWF49639.1 - 3e-119 395.6 18.1 5.2e-43 147.3 1.3 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF49639.1 - 3.2e-40 137.1 7.1 2e-13 50.9 0.2 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF49639.1 - 3e-12 46.7 0.0 0.0035 17.3 0.0 3.4 3 1 0 3 3 3 3 von Willebrand factor type A domain Copine PF07002.16 OWF49639.1 - 0.0054 16.2 2.4 0.73 9.3 0.2 2.9 3 0 0 3 3 3 2 Copine DUF2201 PF09967.9 OWF49639.1 - 1.8 8.7 6.6 18 5.5 0.2 3.5 4 0 0 4 4 4 0 VWA-like domain (DUF2201) VWA PF00092.28 OWF49640.1 - 3.6e-110 366.0 16.7 2.2e-42 145.3 1.5 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF49640.1 - 7.7e-37 126.2 6.5 7.2e-13 49.1 0.3 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF49640.1 - 2.2e-17 63.4 0.1 4.5e-06 26.7 0.0 3.5 3 1 0 3 3 3 3 von Willebrand factor type A domain vWA-TerF-like PF10138.9 OWF49640.1 - 0.0035 17.5 3.0 0.041 14.0 0.0 3.3 3 1 1 4 4 4 1 vWA found in TerF C terminus Copine PF07002.16 OWF49640.1 - 0.026 14.0 0.6 1.2 8.5 0.0 3.0 3 0 0 3 3 3 0 Copine VWA PF00092.28 OWF49641.1 - 1.2e-116 387.1 14.3 8.5e-39 133.6 0.5 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF49641.1 - 2.1e-40 137.7 3.6 4.1e-15 56.3 0.3 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF49641.1 - 3.2e-09 36.9 0.0 0.039 13.9 0.0 4.3 3 3 0 3 3 3 3 von Willebrand factor type A domain Sec23_trunk PF04811.15 OWF49641.1 - 0.005 16.4 0.6 1.6 8.3 0.1 2.6 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Peptidase_MA_2 PF13485.6 OWF49641.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Copine PF07002.16 OWF49641.1 - 0.013 15.0 0.7 6 6.2 0.0 2.9 3 1 0 3 3 3 0 Copine ClpB_D2-small PF10431.9 OWF49641.1 - 0.061 13.4 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Pox_F15 PF04596.12 OWF49643.1 - 0.049 13.4 20.9 6.2 6.6 0.9 4.8 1 1 5 6 6 6 0 Poxvirus protein F15 DUF4628 PF15429.6 OWF49643.1 - 0.94 9.1 45.6 45 3.6 1.6 10.1 1 1 7 8 8 8 0 Domain of unknown function (DUF4628) Fibrinogen_C PF00147.18 OWF49644.1 - 2.8e-40 138.5 5.2 2.3e-39 135.5 5.2 1.9 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF49645.1 - 5.7e-15 55.7 0.4 5.8e-15 55.7 0.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain VWA PF00092.28 OWF49646.1 - 1.6e-117 390.0 14.8 1.1e-40 139.7 1.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF49646.1 - 2.5e-42 143.9 1.0 3.1e-15 56.7 0.1 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF49646.1 - 6.5e-13 48.9 0.0 0.0015 18.5 0.0 4.1 3 2 0 3 3 3 3 von Willebrand factor type A domain Sulfotransfer_1 PF00685.27 OWF49647.1 - 1.6e-52 178.6 1.3 4.2e-52 177.3 1.3 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF49647.1 - 9.9e-05 22.8 0.0 0.00071 20.0 0.1 2.0 2 0 0 2 2 2 1 Sulfotransferase family Lectin_C PF00059.21 OWF49648.1 - 1.8e-09 38.3 6.0 2.3e-09 37.9 6.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain PROCT PF08084.11 OWF49648.1 - 3.1e-05 23.9 0.7 4.4e-05 23.4 0.7 1.1 1 0 0 1 1 1 1 PROCT (NUC072) domain Lectin_C PF00059.21 OWF49649.1 - 8.8e-08 32.8 2.8 1.1e-07 32.5 2.8 1.1 1 0 0 1 1 1 1 Lectin C-type domain PROCT PF08084.11 OWF49649.1 - 0.0015 18.5 0.2 0.002 18.1 0.2 1.2 1 0 0 1 1 1 1 PROCT (NUC072) domain Usp PF00582.26 OWF49650.1 - 1.9e-20 73.8 0.1 1.9e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 Universal stress protein family FtsK_SpoIIIE PF01580.18 OWF49650.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-B_box PF00643.24 OWF49651.1 - 3.3e-11 43.2 27.5 1.5e-06 28.2 9.0 2.9 3 0 0 3 3 3 2 B-box zinc finger SGL PF08450.12 OWF49651.1 - 0.00059 19.5 0.6 0.62 9.6 0.0 3.4 1 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF49651.1 - 0.0033 17.4 2.8 20 5.5 0.0 4.2 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.11 OWF49651.1 - 0.014 15.5 0.1 0.31 11.4 0.0 3.1 3 0 0 3 3 2 0 Two component regulator propeller DUF5082 PF16888.5 OWF49651.1 - 0.14 12.4 15.4 0.18 12.1 12.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 OWF49651.1 - 0.57 9.5 2.7 0.91 8.8 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 OWF49651.1 - 0.63 10.1 17.1 0.84 9.7 7.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 OWF49651.1 - 0.82 8.5 5.3 1.1 8.1 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_M15_2 PF05951.13 OWF49651.1 - 3.4 7.3 10.6 0.58 9.8 0.3 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF882) DUF948 PF06103.11 OWF49651.1 - 7.4 6.9 6.9 6.5 7.1 0.6 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 OWF49651.1 - 8 6.8 18.2 0.061 13.6 1.3 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Med31 PF05669.12 OWF49652.1 - 1.2e-06 28.5 0.1 1.4e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 SOH1 Uteroglobin PF01099.17 OWF49653.1 - 0.027 14.8 0.2 0.081 13.3 0.0 1.9 2 0 0 2 2 2 0 Uteroglobin family Lig_chan-Glu_bd PF10613.9 OWF49654.1 - 4.4e-24 84.9 0.0 3.3e-23 82.1 0.0 2.5 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 OWF49654.1 - 8.3e-23 80.9 0.1 1.5e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OWF49654.1 - 3.4e-16 59.4 0.0 1.2e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 MFS_1 PF07690.16 OWF49656.1 - 5.2e-25 88.1 30.9 2.2e-14 53.2 10.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF49656.1 - 0.00038 19.4 6.2 0.00097 18.1 5.0 1.7 1 1 0 1 1 1 1 MFS_1 like family TMEM234 PF10639.9 OWF49656.1 - 0.012 15.6 0.3 0.012 15.6 0.3 2.4 3 0 0 3 3 3 0 Putative transmembrane family 234 NADHdh-2_N PF12155.8 OWF49656.1 - 3.2 8.2 8.5 0.57 10.6 1.6 3.2 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 N-terminal Astacin PF01400.24 OWF49657.1 - 6.3e-54 182.5 0.0 1e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 OWF49657.1 - 2.3e-20 72.8 93.5 3e-06 27.7 10.9 6.4 6 0 0 6 6 6 5 ShK domain-like DUF3606 PF12244.8 OWF49657.1 - 0.066 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Peptidase_M10 PF00413.24 OWF49657.1 - 0.076 12.9 1.9 0.24 11.3 1.9 1.8 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 OWF49657.1 - 0.17 10.8 0.2 0.29 10.1 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 zf-CCCH PF00642.24 OWF49657.1 - 1.2 9.1 7.6 28 4.8 0.1 4.2 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_8 PF13855.6 OWF49658.1 - 8.7e-12 44.6 15.3 1.1e-11 44.3 3.0 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OWF49658.1 - 1.4e-08 34.9 13.3 5.1e-05 23.6 0.1 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF49658.1 - 0.00012 22.1 12.2 0.9 10.3 0.0 5.9 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 OWF49658.1 - 0.0011 18.8 8.8 0.95 9.7 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich repeat Arginase PF00491.21 OWF49659.1 - 1.9e-86 290.0 0.0 2.5e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OWF49659.1 - 0.066 13.4 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 UPF0489 domain Ion_trans PF00520.31 OWF49660.1 - 2.5e-128 426.4 109.8 1.8e-36 125.6 21.7 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 OWF49660.1 - 0.0013 17.5 1.3 0.0013 17.5 1.3 8.6 7 3 3 10 10 10 4 Polycystin cation channel Sod_Fe_C PF02777.18 OWF49660.1 - 1.3 9.2 3.6 6 7.1 0.2 2.9 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, C-terminal domain 7tm_1 PF00001.21 OWF49661.1 - 9.5e-14 51.3 16.9 1.3e-13 50.9 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Neurexophilin PF06312.12 OWF49662.1 - 5.6e-07 29.2 0.2 9.9e-07 28.4 0.2 1.3 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF49662.1 - 5.8e-05 23.9 0.0 0.00013 22.8 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Invasin_D3 PF09134.10 OWF49662.1 - 0.0095 16.2 0.6 0.019 15.3 0.6 1.4 1 0 0 1 1 1 1 Invasin, domain 3 Cadherin_5 PF17892.1 OWF49662.1 - 0.097 12.7 0.5 0.22 11.5 0.5 1.6 1 0 0 1 1 1 0 Cadherin-like domain Nuc_deoxyrib_tr PF05014.15 OWF49663.1 - 1.9e-14 53.8 0.0 3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Rhomboid PF01694.22 OWF49663.1 - 3.2e-06 27.2 1.0 5.9e-06 26.4 1.0 1.3 1 0 0 1 1 1 1 Rhomboid family ABC_membrane PF00664.23 OWF49664.1 - 9.8e-59 199.2 35.1 1.2e-40 140.0 17.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF49664.1 - 1.9e-49 167.7 0.1 3.8e-28 98.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF49664.1 - 1.1e-08 34.8 7.8 0.00058 19.4 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 OWF49664.1 - 0.00014 21.7 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein MMR_HSR1 PF01926.23 OWF49664.1 - 0.00051 20.1 2.0 0.96 9.6 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF49664.1 - 0.0014 18.6 2.0 0.095 12.6 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OWF49664.1 - 0.0015 18.2 0.5 0.7 9.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OWF49664.1 - 0.0018 18.1 1.4 2.8 7.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 OWF49664.1 - 0.0019 18.3 4.4 0.0022 18.1 0.0 2.8 3 0 0 3 3 3 1 Dynamin family AAA_18 PF13238.6 OWF49664.1 - 0.013 16.0 0.2 6.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OWF49664.1 - 0.034 13.9 1.9 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family fragilysinNterm PF16376.5 OWF49664.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of fragilysin AAA_7 PF12775.7 OWF49664.1 - 0.17 11.4 0.2 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 OWF49664.1 - 0.42 10.9 3.8 22 5.3 0.2 3.2 2 1 0 2 2 2 0 AAA domain Dzip-like_N PF13815.6 OWF49665.1 - 5.3e-38 129.6 5.2 5.3e-38 129.6 5.2 4.5 4 1 1 5 5 5 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_4 PF13894.6 OWF49665.1 - 0.0053 17.5 1.6 0.013 16.2 1.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 OWF49665.1 - 0.0056 16.9 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OWF49665.1 - 0.018 15.5 2.0 0.052 14.0 2.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OWF49665.1 - 0.14 12.5 0.8 0.31 11.4 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding HflK_N PF12221.8 OWF49666.1 - 0.00023 21.1 12.1 31 4.7 0.0 8.7 11 0 0 11 11 11 2 Bacterial membrane protein N terminal GET2 PF08690.10 OWF49666.1 - 0.0018 18.0 56.5 0.65 9.6 9.5 5.9 1 1 5 6 6 6 6 GET complex subunit GET2 Spc7 PF08317.11 OWF49666.1 - 0.15 11.0 12.3 0.73 8.7 0.7 3.5 2 1 3 5 5 5 0 Spc7 kinetochore protein Dicty_CTDC PF00526.18 OWF49667.1 - 4.8 7.2 13.9 5.7 6.9 1.7 3.9 3 0 0 3 3 3 0 Dictyostelium (slime mold) repeat DUF4744 PF15918.5 OWF49668.1 - 1.9e-05 25.4 8.7 0.00099 19.9 1.9 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4744) NLE PF08154.12 OWF49668.1 - 1.4 9.5 2.6 73 4.0 0.1 3.8 1 1 2 3 3 3 0 NLE (NUC135) domain Peroxin-3 PF04882.12 OWF49669.1 - 2.8e-56 191.5 5.2 2.2e-38 132.5 2.0 3.0 1 1 1 2 2 2 2 Peroxin-3 DUF2828 PF11443.8 OWF49669.1 - 0.0026 15.9 0.0 0.003 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) UcrQ PF02939.16 OWF49669.1 - 0.034 14.1 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 UcrQ family Tetraspanin PF00335.20 OWF49670.1 - 9.1e-34 117.1 5.7 1.1e-33 116.8 5.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 OWF49670.1 - 0.024 13.4 2.4 0.27 10.0 2.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Consortin_C PF15281.6 OWF49670.1 - 0.12 12.4 0.9 1 9.4 0.2 2.5 2 1 1 3 3 3 0 Consortin C-terminus DUF4293 PF14126.6 OWF49670.1 - 0.21 11.8 8.6 0.065 13.5 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) TarH PF02203.15 OWF49670.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.8 1 1 2 3 3 3 0 Tar ligand binding domain homologue Claudin_2 PF13903.6 OWF49670.1 - 2.1 8.1 11.8 0.2 11.4 2.3 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DctQ PF04290.12 OWF49670.1 - 4.1 7.3 13.8 0.08 12.9 2.1 2.8 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Steroid_dh PF02544.16 OWF49671.1 - 1.2e-41 142.2 3.5 1.2e-41 142.2 3.5 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OWF49671.1 - 2.9e-09 36.8 0.9 6.1e-09 35.8 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OWF49671.1 - 4e-06 27.2 0.3 4e-06 27.2 0.3 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase FtsX PF02687.21 OWF49671.1 - 5 7.7 7.9 4.7 7.7 0.2 3.2 3 1 0 3 3 3 0 FtsX-like permease family YjbR PF04237.13 OWF49673.1 - 0.097 13.2 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 YjbR Neurexophilin PF06312.12 OWF49674.1 - 1.1e-07 31.5 0.4 2.2e-07 30.6 0.4 1.5 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF49674.1 - 0.0016 19.3 0.0 0.0033 18.2 0.0 1.6 1 0 0 1 1 1 1 Filamin/ABP280 repeat Invasin_D3 PF09134.10 OWF49674.1 - 0.05 13.9 0.4 0.093 13.0 0.4 1.4 1 0 0 1 1 1 0 Invasin, domain 3 Cadherin_5 PF17892.1 OWF49674.1 - 0.11 12.5 0.5 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Cadherin-like domain RuBisCO_large_N PF02788.16 OWF49675.1 - 2.9 8.1 42.5 29 4.9 1.3 9.6 1 1 7 10 10 10 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain NGP1NT PF08153.12 OWF49675.1 - 3.3 7.9 35.6 9.4 6.4 0.9 8.1 1 1 7 8 8 8 0 NGP1NT (NUC091) domain 7tm_1 PF00001.21 OWF49676.1 - 8.1e-23 81.1 20.1 1.2e-22 80.5 20.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 OWF49677.1 - 1.6e-28 99.7 34.7 2.2e-22 79.5 17.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF49677.1 - 0.0047 15.8 5.3 0.0047 15.8 5.3 3.7 2 1 1 3 3 3 2 MFS_1 like family DUF3392 PF11872.8 OWF49677.1 - 1.5 9.1 13.7 4.8 7.5 3.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) CENP-I PF07778.11 OWF49678.1 - 2.2e-111 373.1 5.1 2.8e-111 372.8 5.1 1.1 1 0 0 1 1 1 1 Mis6 CEP63 PF17045.5 OWF49680.1 - 7.7e-56 190.0 47.1 7.7e-56 190.0 47.1 4.6 3 1 0 4 4 4 2 Centrosomal protein of 63 kDa Tropomyosin_1 PF12718.7 OWF49680.1 - 5.9e-05 23.3 13.9 5.9e-05 23.3 13.9 7.1 2 1 4 7 7 7 1 Tropomyosin like Baculo_PEP_C PF04513.12 OWF49680.1 - 0.00012 22.2 2.2 0.00012 22.2 2.2 6.0 4 2 2 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus Yop-YscD_cpl PF16697.5 OWF49680.1 - 1.2 9.5 8.1 2.7 8.4 0.3 3.7 3 0 0 3 3 3 0 Inner membrane component of T3SS, cytoplasmic domain DUF3584 PF12128.8 OWF49680.1 - 2.2 5.7 110.2 2 5.8 34.2 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) COMM_domain PF07258.14 OWF49681.1 - 2.2e-16 59.8 0.2 7e-16 58.1 0.1 1.9 2 0 0 2 2 2 1 COMM domain Clr5 PF14420.6 OWF49681.1 - 0.015 15.5 0.2 0.032 14.4 0.2 1.6 1 0 0 1 1 1 0 Clr5 domain DUF2935 PF11155.8 OWF49681.1 - 0.041 14.2 0.6 0.079 13.3 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF229 PF02995.17 OWF49683.1 - 7.2e-120 400.9 7.0 1.1e-119 400.3 1.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF49683.1 - 0.00029 20.4 0.0 0.00083 18.8 0.0 1.8 1 1 1 2 2 2 1 Sulfatase AAA_34 PF13872.6 OWF49684.1 - 1.3e-122 408.4 0.0 2e-122 407.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 OWF49684.1 - 7e-110 367.0 0.3 1.1e-109 366.3 0.3 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 OWF49684.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF49684.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase COesterase PF00135.28 OWF49685.1 - 2.7e-160 534.6 0.0 3.1e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF49685.1 - 2e-06 27.8 0.2 6.4e-06 26.2 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold AChE_tetra PF08674.10 OWF49685.1 - 2.1e-06 27.3 7.3 6.1e-06 25.8 7.3 1.9 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain DUF423 PF04241.15 OWF49687.1 - 5.3e-21 74.6 0.1 8.1e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Peptidase_C3G PF12381.8 OWF49687.1 - 0.034 13.6 0.3 5.6 6.4 0.1 2.1 1 1 1 2 2 2 0 Tungro spherical virus-type peptidase MAPEG PF01124.18 OWF49688.1 - 2e-19 69.8 0.2 2.2e-19 69.6 0.2 1.0 1 0 0 1 1 1 1 MAPEG family zf-C4 PF00105.18 OWF49689.1 - 7.7e-30 103.2 12.9 7.7e-30 103.2 12.9 2.8 4 0 0 4 4 4 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF49689.1 - 2.6e-09 37.0 6.9 8.1e-09 35.4 6.9 1.8 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor IQ PF00612.27 OWF49690.1 - 3e-127 402.6 382.4 0.00019 20.9 0.3 68.3 71 0 0 71 71 71 49 IQ calmodulin-binding motif ASH PF15780.5 OWF49690.1 - 5.8e-23 80.9 0.0 2.2e-22 79.1 0.0 2.1 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 OWF49690.1 - 6.2e-17 61.8 0.3 4.4e-07 30.0 0.0 3.6 3 1 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OWF49690.1 - 8.4e-09 35.2 0.1 3.8e-06 26.6 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 OWF49690.1 - 0.0021 18.1 4.2 13 6.0 0.0 5.6 5 0 0 5 5 5 2 CH-like domain in sperm protein Pectate_lyase22 PF14583.6 OWF49690.1 - 0.0022 16.7 0.1 26 3.3 0.0 5.1 6 0 0 6 6 6 0 Oligogalacturonate lyase HTH_16 PF12645.7 OWF49690.1 - 0.086 12.9 0.0 13 5.9 0.1 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain Arm-DNA-bind_2 PF12167.8 OWF49690.1 - 0.65 10.0 3.9 1.4 8.8 0.3 3.7 4 0 0 4 4 4 0 Arm DNA-binding domain Ctr PF04145.15 OWF49691.1 - 6.4e-21 75.5 0.1 1e-20 74.8 0.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF3099 PF11298.8 OWF49691.1 - 0.086 13.0 0.2 0.086 13.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) DUF2897 PF11446.8 OWF49691.1 - 1.4 8.9 3.2 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) zf-C3HC4_3 PF13920.6 OWF49692.1 - 1.3e-09 37.7 14.7 1.3e-09 37.7 14.7 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF49692.1 - 0.00068 19.5 16.1 0.00068 19.5 16.1 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF49692.1 - 0.0014 18.4 14.6 0.0014 18.4 14.6 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OWF49692.1 - 0.012 15.6 13.1 0.082 13.0 13.1 2.5 1 0 0 1 1 1 0 RING-type zinc-finger MinE PF03776.14 OWF49692.1 - 0.015 15.3 0.1 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE zf-RING_5 PF14634.6 OWF49692.1 - 0.022 14.7 16.7 0.022 14.7 16.7 3.6 3 1 1 4 4 4 0 zinc-RING finger domain Claudin_2 PF13903.6 OWF49692.1 - 0.84 9.4 24.4 6.7 6.4 6.4 3.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SRCR PF00530.18 OWF49694.1 - 4e-114 373.8 43.8 1.4e-24 86.5 3.9 5.7 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF49694.1 - 4.9e-25 87.9 28.4 5.4e-05 23.7 0.2 6.2 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF49694.1 - 4.7e-08 33.5 5.4 0.34 11.4 0.1 5.8 5 1 0 6 6 6 3 Hepsin, SRCR domain P5-ATPase PF12409.8 OWF49694.1 - 0.14 12.3 0.2 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 P5-type ATPase cation transporter SRCR PF00530.18 OWF49695.1 - 0 1571.9 165.2 6.1e-31 106.9 2.2 19.1 19 0 0 19 19 19 18 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF49695.1 - 6.6e-98 321.6 74.9 1e-05 25.9 0.1 18.7 18 0 0 18 18 18 18 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF49695.1 - 1.8e-38 131.4 12.7 2.2 8.8 0.0 18.6 18 0 0 18 18 18 13 Hepsin, SRCR domain Ldl_recept_a PF00057.18 OWF49695.1 - 2.1e-15 56.6 26.2 7.2e-07 29.3 9.4 5.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF4758 PF15950.5 OWF49695.1 - 6.4e-05 23.3 17.4 8.3 6.8 0.1 9.1 10 0 0 10 10 10 1 Putative sperm flagellar membrane protein Ig_3 PF13927.6 OWF49695.1 - 0.0012 19.5 1.2 0.0047 17.5 0.2 2.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF49695.1 - 0.01 15.9 0.1 0.032 14.3 0.1 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain Trypan_PARP PF05887.11 OWF49695.1 - 0.25 11.3 8.8 0.3 11.1 5.8 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Baculo_PEP_C PF04513.12 OWF49695.1 - 2.1 8.4 13.0 1.2 9.1 6.8 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TonB_N PF16031.5 OWF49695.1 - 3.1 8.3 9.8 13 6.3 9.8 2.0 1 0 0 1 1 1 0 TonB polyproline region SRCR PF00530.18 OWF49696.1 - 1.4e-83 275.8 20.7 3.3e-29 101.3 2.4 3.8 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF49696.1 - 1.7e-14 54.1 13.8 0.0001 22.7 0.9 3.9 4 0 0 4 4 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF49696.1 - 2e-08 34.7 0.0 0.077 13.5 0.0 3.5 3 0 0 3 3 3 2 Hepsin, SRCR domain DUF2353 PF09789.9 OWF49696.1 - 0.0066 15.8 0.3 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 OWF49696.1 - 0.019 15.2 0.7 0.032 14.5 0.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 OWF49696.1 - 0.022 15.2 0.6 0.053 14.0 0.6 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3573 PF12097.8 OWF49696.1 - 0.048 12.5 0.8 0.091 11.6 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) SF-assemblin PF06705.11 OWF49696.1 - 0.053 12.9 0.7 0.078 12.3 0.7 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin FlaC_arch PF05377.11 OWF49696.1 - 0.063 13.7 2.0 0.13 12.6 2.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIVA PF05103.13 OWF49696.1 - 0.065 13.3 0.8 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 DivIVA protein bZIP_2 PF07716.15 OWF49696.1 - 0.079 13.1 1.4 0.13 12.4 1.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Prefoldin PF02996.17 OWF49696.1 - 0.081 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Prefoldin subunit SKA2 PF16740.5 OWF49696.1 - 0.088 12.6 1.9 0.3 10.9 0.3 2.5 3 0 0 3 3 2 0 Spindle and kinetochore-associated protein 2 LPP PF04728.13 OWF49696.1 - 0.1 13.0 2.0 0.19 12.1 2.0 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 OWF49696.1 - 0.11 12.9 0.5 0.21 11.9 0.2 1.6 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Histone_HNS PF00816.21 OWF49696.1 - 0.12 13.2 0.7 26 5.7 0.3 2.3 2 0 0 2 2 2 0 H-NS histone family DivIC PF04977.15 OWF49696.1 - 0.12 12.1 0.4 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 Septum formation initiator FliD_N PF02465.18 OWF49696.1 - 0.14 12.8 0.2 0.27 11.9 0.2 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.11 OWF49696.1 - 0.15 10.9 1.7 0.23 10.3 1.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Wtap PF17098.5 OWF49696.1 - 0.16 11.9 1.4 0.27 11.1 1.4 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Siah-Interact_N PF09032.11 OWF49696.1 - 0.17 12.2 0.4 0.35 11.2 0.4 1.5 1 0 0 1 1 1 0 Siah interacting protein, N terminal DUF4349 PF14257.6 OWF49696.1 - 0.2 11.1 1.0 0.34 10.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) RGM_N PF06535.12 OWF49696.1 - 0.22 11.7 4.9 0.44 10.7 0.3 3.0 2 1 1 3 3 3 0 Repulsive guidance molecule (RGM) N-terminus TolA_bind_tri PF16331.5 OWF49696.1 - 0.26 11.4 9.8 0.13 12.3 5.2 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation HalX PF08663.10 OWF49696.1 - 0.46 10.8 2.4 0.86 10.0 2.4 1.4 1 0 0 1 1 1 0 HalX domain Prefoldin_2 PF01920.20 OWF49696.1 - 0.5 10.3 3.6 0.94 9.5 3.6 1.4 1 0 0 1 1 1 0 Prefoldin subunit SlyX PF04102.12 OWF49696.1 - 1.3 9.7 6.6 0.15 12.7 2.1 1.8 2 0 0 2 2 1 0 SlyX Csm1_N PF18504.1 OWF49696.1 - 3.3 8.1 4.8 6.4 7.2 4.8 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain TSP_1 PF00090.19 OWF49699.1 - 1.5e-17 63.5 70.2 8.8e-05 22.6 2.4 6.7 6 0 0 6 6 6 6 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 OWF49699.1 - 0.00088 19.3 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 7tm_1 PF00001.21 OWF49700.1 - 1.5e-18 67.1 25.4 1.5e-18 67.1 25.4 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) ECF_trnsprt PF12822.7 OWF49700.1 - 0.14 12.3 12.0 38 4.3 12.1 3.0 1 1 1 2 2 2 0 ECF transporter, substrate-specific component DUF1345 PF07077.11 OWF49700.1 - 4.8 6.9 7.5 5.2 6.7 1.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1345) zf-C3HC4 PF00097.25 OWF49701.1 - 2e-10 40.3 10.2 4.5e-10 39.2 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF49701.1 - 6.5e-10 38.9 10.2 1.8e-09 37.5 10.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF49701.1 - 6.1e-08 32.7 8.7 6.1e-08 32.7 8.7 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF49701.1 - 6.6e-08 32.3 11.4 6.6e-08 32.3 11.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF49701.1 - 1.3e-06 28.2 10.3 3.7e-06 26.7 10.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF49701.1 - 4.1e-06 27.0 13.6 4.1e-06 27.0 13.6 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OWF49701.1 - 8.7e-06 25.5 8.8 8.7e-06 25.5 8.8 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF49701.1 - 0.00018 21.4 12.9 0.00055 19.8 12.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain SGL PF08450.12 OWF49701.1 - 0.015 14.9 0.1 0.21 11.2 0.0 2.6 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF49701.1 - 0.029 14.4 2.3 3.4 7.9 0.0 4.3 5 0 0 5 5 4 0 NHL repeat zf-Sec23_Sec24 PF04810.15 OWF49701.1 - 0.065 13.3 2.4 3.1 7.9 1.6 3.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rad50_zn_hook PF04423.14 OWF49701.1 - 0.23 11.3 3.6 5.4 6.9 0.6 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 OWF49701.1 - 0.24 11.7 8.0 0.66 10.3 8.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OWF49701.1 - 0.37 10.6 8.2 0.31 10.8 0.9 3.4 2 1 1 3 3 3 0 RING-like zinc finger zf-RING_4 PF14570.6 OWF49701.1 - 0.92 9.4 11.2 2.3 8.1 9.2 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OWF49701.1 - 1.5 9.2 10.5 0.13 12.6 3.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding 7tm_1 PF00001.21 OWF49702.1 - 2.5e-11 43.4 26.7 3.3e-11 43.0 25.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.6 OWF49702.1 - 0.068 13.1 3.3 0.32 10.9 0.3 2.6 2 0 0 2 2 2 0 TMEM154 protein family Pox_RNA_pol_35 PF03396.15 OWF49703.1 - 0.13 11.5 0.9 15 4.7 0.1 2.9 1 1 2 3 3 3 0 Poxvirus DNA-directed RNA polymerase, 35 kD subunit Chlam_OMP6 PF03504.13 OWF49703.1 - 1.4 9.2 8.1 17 5.8 0.5 3.3 1 1 3 4 4 4 0 Chlamydia cysteine-rich outer membrane protein 6 AWS PF17907.1 OWF49703.1 - 4.3 7.5 21.4 2.3 8.3 0.5 4.4 2 1 3 5 5 5 0 AWS domain 7tm_1 PF00001.21 OWF49704.1 - 1.2e-17 64.1 19.1 1.8e-17 63.5 19.1 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RSN1_TM PF13967.6 OWF49704.1 - 0.017 14.9 2.8 0.035 13.9 1.9 2.0 1 1 1 2 2 2 0 Late exocytosis, associated with Golgi transport TMEM154 PF15102.6 OWF49704.1 - 0.069 13.1 0.8 0.55 10.1 0.1 2.5 2 0 0 2 2 2 0 TMEM154 protein family CPSF73-100_C PF11718.8 OWF49705.1 - 2.1e-51 174.6 0.5 4.1e-51 173.6 0.5 1.5 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OWF49705.1 - 9.4e-33 112.8 0.0 2.1e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 OWF49705.1 - 2.3e-21 75.4 0.0 4.8e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OWF49705.1 - 1.1e-12 48.3 0.1 2.4e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OWF49705.1 - 9e-11 41.6 0.0 1.8e-07 30.8 0.0 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OWF49705.1 - 1.7e-06 27.7 0.1 2.9e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OWF49705.1 - 0.00066 19.6 0.8 0.013 15.4 0.1 3.0 2 1 1 3 3 3 2 Beta-lactamase superfamily domain DUF4891 PF16232.5 OWF49705.1 - 0.034 14.7 0.0 0.082 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4891) polyprenyl_synt PF00348.17 OWF49706.1 - 1.5e-92 309.3 0.3 2e-92 308.9 0.3 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 OWF49706.1 - 0.019 14.3 0.7 0.31 10.4 0.1 2.3 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain DUF547 PF04784.14 OWF49707.1 - 1.3e-33 115.7 0.0 2.1e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 TPP_enzyme_N PF02776.18 OWF49708.1 - 4.3e-51 172.9 0.5 1.2e-50 171.5 0.5 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OWF49708.1 - 4e-20 72.2 0.1 2.1e-18 66.6 0.2 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OWF49708.1 - 1.4e-15 57.2 0.1 1.4e-14 54.0 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain zf-H2C2_2 PF13465.6 OWF49709.1 - 1.7e-36 123.0 49.4 1.8e-09 37.6 1.2 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 OWF49709.1 - 4e-27 93.1 51.0 1.9e-05 24.9 0.4 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF49709.1 - 3.9e-15 55.2 48.6 0.0026 18.4 0.4 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF49709.1 - 7.5e-06 26.2 17.1 0.003 17.8 3.9 3.1 1 1 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 OWF49709.1 - 7e-05 23.0 15.4 0.12 12.7 0.2 5.7 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 OWF49709.1 - 0.00032 20.9 24.8 0.05 13.7 0.4 5.5 2 2 4 6 6 6 3 Aberrant zinc-finger zf-TRAF PF02176.18 OWF49709.1 - 0.0014 19.3 1.5 0.0014 19.3 1.5 3.9 3 2 1 4 4 4 1 TRAF-type zinc finger CopK PF11525.8 OWF49709.1 - 0.021 14.4 0.3 69 3.2 0.0 4.4 2 2 1 4 4 4 0 Copper resistance protein K zf-MYST PF17772.1 OWF49709.1 - 0.2 11.3 3.0 0.34 10.5 1.2 2.2 2 0 0 2 2 2 0 MYST family zinc finger domain DUF629 PF04780.12 OWF49709.1 - 2.5 6.5 9.5 1.3 7.5 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-met PF12874.7 OWF49709.1 - 9.7 6.7 17.2 24 5.5 0.0 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type TPR_1 PF00515.28 OWF49710.1 - 0.0006 19.5 25.4 2.1 8.3 0.5 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF49710.1 - 0.0018 17.9 7.2 0.015 15.0 0.0 5.3 7 0 0 7 7 7 1 TPR repeat TPR_17 PF13431.6 OWF49710.1 - 0.0033 17.7 7.5 21 5.8 0.2 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF49710.1 - 0.016 16.0 3.7 71 4.6 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF49710.1 - 1.4 9.2 34.8 2.5 8.4 0.2 9.8 12 0 0 12 12 12 0 Tetratricopeptide repeat zf-C2H2_6 PF13912.6 OWF49711.1 - 0.06 13.4 1.1 0.19 11.8 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF49711.1 - 0.098 13.2 0.7 0.098 13.2 0.7 2.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type ARS2 PF04959.13 OWF49711.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 TIR PF01582.20 OWF49712.1 - 2.7e-18 66.4 0.2 5.5e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF49712.1 - 9.4e-18 64.9 0.0 1.8e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF49712.1 - 6.7e-06 26.4 13.2 0.00047 20.5 0.3 4.9 3 2 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF49712.1 - 0.00017 21.3 6.0 0.019 14.7 0.9 4.5 3 1 0 3 3 3 1 Leucine rich repeat Multi-haem_cyto PF13447.6 OWF49712.1 - 0.035 13.4 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Seven times multi-haem cytochrome CxxCH TIR-like PF10137.9 OWF49712.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF1863 PF08937.11 OWF49712.1 - 0.093 13.1 0.1 0.82 10.0 0.1 2.3 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) SKG6 PF08693.10 OWF49712.1 - 0.48 9.9 2.1 1 8.8 2.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_6 PF13516.6 OWF49712.1 - 0.98 9.6 5.5 36 4.8 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OWF49712.1 - 2.1 9.2 14.7 25 5.9 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat F-box PF00646.33 OWF49713.1 - 0.008 16.0 1.4 0.023 14.6 0.3 2.3 2 0 0 2 2 2 1 F-box domain CK_II_beta PF01214.18 OWF49714.1 - 2.9e-75 252.1 0.1 3.5e-75 251.8 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 OWF49714.1 - 0.11 12.7 0.3 0.26 11.5 0.3 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain SAM_3 PF18016.1 OWF49715.1 - 0.06 13.2 0.1 0.2 11.5 0.1 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glyco_transf_25 PF01755.17 OWF49716.1 - 2.1e-33 115.9 0.0 6.7e-32 111.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 OWF49716.1 - 1.5e-11 44.6 1.7 3.2e-11 43.6 1.7 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 OWF49716.1 - 1.2e-10 41.3 1.0 2e-10 40.6 1.0 1.2 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 OWF49716.1 - 0.044 13.6 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Lustrin_cystein PF14625.6 OWF49717.1 - 1.3e-07 31.8 87.9 0.12 12.8 8.9 6.5 6 0 0 6 6 6 6 Lustrin, cysteine-rich repeated domain Thyroglobulin_1 PF00086.18 OWF49718.1 - 1e-38 130.8 30.8 1.2e-14 53.7 6.3 5.1 3 0 0 3 3 3 3 Thyroglobulin type-1 repeat Kunitz_BPTI PF00014.23 OWF49718.1 - 3.5e-37 126.4 39.0 2.8e-17 62.7 11.4 6.4 4 0 0 4 4 4 3 Kunitz/Bovine pancreatic trypsin inhibitor domain WAP PF00095.21 OWF49718.1 - 9.1e-26 90.0 89.2 2.5e-10 40.6 17.7 26.2 20 5 7 27 27 27 5 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lustrin_cystein PF14625.6 OWF49718.1 - 4.4e-05 23.8 7.6 4.4e-05 23.8 7.6 27.3 27 2 2 29 29 29 12 Lustrin, cysteine-rich repeated domain TMEM154 PF15102.6 OWF49718.1 - 0.1 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family BatA PF07584.11 OWF49718.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal SCAI PF12070.8 OWF49719.1 - 7.2e-227 754.5 0.8 8.6e-227 754.2 0.9 1.1 1 0 0 1 1 1 1 Protein SCAI Peptidase_M90 PF06167.12 OWF49719.1 - 0.016 14.8 0.1 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 Mur_ligase_M PF08245.12 OWF49720.1 - 0.0013 18.8 0.1 0.0064 16.5 0.0 2.2 1 1 1 2 2 2 1 Mur ligase middle domain FtsJ PF01728.19 OWF49722.1 - 3.4e-26 92.4 0.0 6.8e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase dsrm PF00035.26 OWF49723.1 - 8.2e-07 29.6 0.0 0.31 11.8 0.0 4.7 4 0 0 4 4 4 3 Double-stranded RNA binding motif PLA2_B PF01735.18 OWF49724.1 - 2.1e-76 257.3 0.0 2e-75 254.1 0.0 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.30 OWF49724.1 - 8.3e-13 48.5 0.0 1.9e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain Patatin PF01734.22 OWF49724.1 - 0.017 15.3 0.4 0.95 9.6 0.1 2.4 2 1 0 2 2 2 0 Patatin-like phospholipase TSA PF03249.13 OWF49724.1 - 0.035 12.9 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Type specific antigen DUF4637 PF15470.6 OWF49724.1 - 9.7 5.9 11.0 19 4.9 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) An_peroxidase PF03098.15 OWF49726.1 - 1.9e-47 162.1 0.0 1.1e-42 146.3 0.0 2.4 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.27 OWF49726.1 - 0.0021 18.3 11.1 0.0044 17.3 11.1 1.5 1 0 0 1 1 1 1 EGF-like domain TPR_1 PF00515.28 OWF49727.1 - 1.7e-09 37.1 5.0 6.5e-08 32.1 0.1 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF49727.1 - 9e-09 34.8 0.9 1.2e-06 28.2 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 OWF49727.1 - 8.1e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 BDBT FKBP like N-terminal TPR_11 PF13414.6 OWF49727.1 - 5.1e-05 22.9 2.7 0.00026 20.6 0.8 3.0 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 OWF49727.1 - 5.3e-05 23.1 0.4 0.00039 20.4 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat HemY_N PF07219.13 OWF49727.1 - 0.009 16.2 0.2 0.98 9.6 0.1 2.9 2 1 1 3 3 3 1 HemY protein N-terminus TPR_16 PF13432.6 OWF49727.1 - 0.014 16.0 0.3 0.13 12.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF49727.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF49727.1 - 0.02 15.7 0.0 0.15 13.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF49727.1 - 0.055 13.9 0.1 0.055 13.9 0.1 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Nse4-Nse3_bdg PF15412.6 OWF49727.1 - 0.056 13.6 0.4 3.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE NERD PF08378.11 OWF49727.1 - 0.1 13.1 0.2 0.52 10.8 0.0 2.0 1 1 1 2 2 2 0 Nuclease-related domain GRIP PF01465.20 OWF49728.1 - 2.4e-13 49.8 1.0 7.3e-13 48.2 1.0 1.9 1 0 0 1 1 1 1 GRIP domain ATG16 PF08614.11 OWF49728.1 - 0.0016 18.7 16.8 0.0016 18.7 16.8 6.9 2 2 5 7 7 7 2 Autophagy protein 16 (ATG16) SlyX PF04102.12 OWF49728.1 - 0.0088 16.6 4.0 0.0088 16.6 4.0 11.6 5 3 8 13 13 13 4 SlyX P16-Arc PF04699.14 OWF49729.1 - 4.3e-45 153.8 1.7 3.8e-44 150.7 1.7 1.9 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 OWF49729.1 - 0.0039 17.5 0.0 0.005 17.1 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family PBP1_TM PF14812.6 OWF49729.1 - 5.6 7.4 6.7 60 4.1 6.7 2.0 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L29 PF00831.23 OWF49730.1 - 5.3e-19 67.9 2.0 5.3e-19 67.9 2.0 2.4 2 1 0 2 2 2 1 Ribosomal L29 protein Endonuc_Holl PF10107.9 OWF49730.1 - 0.022 14.6 1.0 0.022 14.6 1.0 1.5 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF737 PF05300.11 OWF49730.1 - 0.077 13.3 8.3 0.092 13.1 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ApoC-I PF04691.12 OWF49730.1 - 1.7 8.6 5.4 1.4 8.9 1.0 2.3 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) zf-RING_UBOX PF13445.6 OWF49731.1 - 3.1e-08 33.5 4.9 3.1e-08 33.5 4.9 3.4 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF49731.1 - 4.8e-08 32.7 6.9 4.8e-08 32.7 6.9 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF49731.1 - 1.5e-07 31.6 6.8 1.5e-07 31.6 6.8 3.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF49731.1 - 8.1e-07 28.9 5.2 8.1e-07 28.9 5.2 3.3 3 1 0 3 3 2 1 zinc-RING finger domain zf-B_box PF00643.24 OWF49731.1 - 1e-06 28.8 36.4 7.3e-05 22.8 6.5 4.7 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 OWF49731.1 - 2.4e-06 27.6 9.1 2.4e-06 27.6 9.1 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF49731.1 - 2.9e-06 27.0 5.7 2.9e-06 27.0 5.7 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF49731.1 - 4.2e-06 26.5 6.7 0.0019 18.2 0.1 4.4 4 0 0 4 4 4 2 NHL repeat zf-C3HC4_2 PF13923.6 OWF49731.1 - 0.00055 19.7 9.3 0.00055 19.7 9.3 3.6 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF49731.1 - 0.001 18.7 1.6 0.012 15.2 0.3 2.5 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OWF49731.1 - 0.003 17.5 0.2 0.0076 16.2 0.2 1.7 1 0 0 1 1 1 1 Beta-propeller repeat zf-Nse PF11789.8 OWF49731.1 - 0.031 14.1 3.8 0.1 12.5 3.8 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OWF49731.1 - 0.27 11.1 15.1 0.021 14.7 7.1 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1722 PF08349.11 OWF49731.1 - 0.34 11.2 1.1 1.2 9.4 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) MukF_M PF17192.4 OWF49731.1 - 1.4 8.7 8.8 2.5 7.8 8.8 1.4 1 0 0 1 1 1 0 MukF middle domain Pup PF05639.11 OWF49731.1 - 2 9.4 5.1 22 6.0 1.1 3.0 1 1 1 2 2 2 0 Pup-like protein MutS_III PF05192.18 OWF49731.1 - 3.1 8.0 5.3 5.7 7.1 5.3 1.4 1 0 0 1 1 1 0 MutS domain III zf-RING_UBOX PF13445.6 OWF49732.1 - 1.4e-08 34.6 4.4 1.4e-08 34.6 4.4 3.5 3 1 1 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF49732.1 - 7e-08 32.2 7.4 7e-08 32.2 7.4 3.8 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF49732.1 - 2.7e-07 30.8 7.0 2.7e-07 30.8 7.0 3.6 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF49732.1 - 1.1e-06 28.5 5.7 1.1e-06 28.5 5.7 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF49732.1 - 1.2e-06 28.6 9.1 1.2e-06 28.6 9.1 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF49732.1 - 3.5e-06 26.8 5.9 3.5e-06 26.8 5.9 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF49732.1 - 0.00024 21.0 13.1 0.00074 19.4 0.2 4.9 4 0 0 4 4 4 1 NHL repeat zf-C3HC4_2 PF13923.6 OWF49732.1 - 0.0005 19.8 9.1 0.0005 19.8 9.1 4.2 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF49732.1 - 0.0011 19.1 34.1 0.0089 16.2 6.2 4.6 4 0 0 4 4 4 2 B-box zinc finger SGL PF08450.12 OWF49732.1 - 0.0014 18.2 1.9 0.017 14.7 0.3 2.7 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OWF49732.1 - 0.0053 16.7 0.4 0.013 15.4 0.4 1.7 1 0 0 1 1 1 1 Beta-propeller repeat DUF1216 PF06746.11 OWF49732.1 - 0.02 14.9 3.4 0.041 13.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) zf-Nse PF11789.8 OWF49732.1 - 0.38 10.6 7.5 0.17 11.7 4.5 2.0 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3450 PF11932.8 OWF49732.1 - 0.86 8.9 11.5 1.4 8.2 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MukF_M PF17192.4 OWF49732.1 - 1.1 8.9 8.8 2 8.1 8.8 1.4 1 0 0 1 1 1 0 MukF middle domain Pup PF05639.11 OWF49732.1 - 2.2 9.2 5.4 25 5.9 1.4 2.9 1 1 1 2 2 2 0 Pup-like protein Prok-RING_4 PF14447.6 OWF49732.1 - 3.6 7.5 20.5 0.023 14.5 7.7 3.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 PHD_2 PF13831.6 OWF49732.1 - 8.7 6.0 10.9 5 6.8 0.4 3.6 3 0 0 3 3 3 0 PHD-finger NHL PF01436.21 OWF49733.1 - 1.4e-05 24.8 7.7 2.2 8.5 0.0 5.1 5 0 0 5 5 5 3 NHL repeat SBBP PF06739.11 OWF49733.1 - 0.0061 16.5 0.8 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Beta-propeller repeat SGL PF08450.12 OWF49733.1 - 0.023 14.3 0.1 1 8.9 0.1 2.9 1 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 OWF49734.1 - 3.1e-10 39.9 3.6 3.1e-10 39.9 3.6 3.2 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF49734.1 - 3.6e-08 33.1 6.8 3.6e-08 33.1 6.8 3.9 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF49734.1 - 5.9e-08 32.9 6.5 5.9e-08 32.9 6.5 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF49734.1 - 1.1e-06 28.4 2.7 1.1e-06 28.4 2.7 4.2 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF49734.1 - 1.5e-06 28.1 5.0 1.5e-06 28.1 5.0 3.6 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF49734.1 - 2.1e-06 27.5 4.5 2.1e-06 27.5 4.5 3.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF49734.1 - 6.7e-06 26.2 9.6 6.7e-06 26.2 9.6 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING NHL PF01436.21 OWF49734.1 - 0.00018 21.4 9.5 4.7 7.4 0.0 5.3 4 0 0 4 4 4 2 NHL repeat zf-Nse PF11789.8 OWF49734.1 - 0.0061 16.3 4.7 0.017 14.9 4.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OWF49734.1 - 0.012 15.5 6.8 0.012 15.5 6.8 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 mIF3 PF14877.6 OWF49734.1 - 0.014 15.0 3.9 0.044 13.5 3.9 1.8 1 0 0 1 1 1 0 Mitochondrial translation initiation factor zf-B_box PF00643.24 OWF49734.1 - 0.018 15.2 6.3 0.018 15.2 6.3 4.1 3 0 0 3 3 3 0 B-box zinc finger SBBP PF06739.11 OWF49734.1 - 0.036 14.1 1.7 0.042 13.9 0.1 2.0 2 0 0 2 2 1 0 Beta-propeller repeat SGL PF08450.12 OWF49734.1 - 0.071 12.7 0.1 1.2 8.7 0.1 2.6 1 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region zf-RING_11 PF17123.5 OWF49734.1 - 0.12 12.1 5.3 0.64 9.8 5.3 2.4 1 0 0 1 1 1 0 RING-like zinc finger LRR_8 PF13855.6 OWF49735.1 - 1.1e-26 92.4 47.7 6.9e-10 38.6 12.1 8.0 7 1 0 8 8 8 5 Leucine rich repeat TIR_2 PF13676.6 OWF49735.1 - 6.4e-14 52.6 0.3 1.8e-13 51.2 0.2 1.8 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 OWF49735.1 - 1.3e-12 47.6 56.6 0.0013 19.1 4.6 11.1 6 2 5 11 11 11 7 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF49735.1 - 2.8e-12 46.8 0.6 4.6e-12 46.1 0.6 1.3 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF49735.1 - 0.00022 21.3 36.7 1.4 9.7 0.4 12.2 12 1 0 12 12 12 2 Leucine Rich Repeat LRR_9 PF14580.6 OWF49735.1 - 0.00068 19.2 2.6 0.00068 19.2 2.6 3.1 4 0 0 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 OWF49735.1 - 0.006 16.5 38.1 7.9 6.8 0.9 11.7 12 0 0 12 12 12 2 Leucine Rich repeat DUF1385 PF07136.11 OWF49735.1 - 0.057 12.7 0.4 0.13 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) CobT PF06213.12 OWF49736.1 - 0.024 14.0 11.7 0.18 11.1 13.1 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RP-C_C PF11800.8 OWF49736.1 - 0.094 12.8 7.9 0.22 11.6 7.9 1.7 1 0 0 1 1 1 0 Replication protein C C-terminal region Asp-B-Hydro_N PF05279.11 OWF49736.1 - 0.22 11.6 16.8 0.12 12.4 14.8 1.6 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PIEZO PF15917.5 OWF49736.1 - 1.3 8.5 9.4 2.6 7.5 9.4 1.5 1 0 0 1 1 1 0 Piezo DUF883 PF05957.13 OWF49736.1 - 1.4 9.6 4.7 8.1 7.1 2.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_transf_10 PF00852.19 OWF49737.1 - 1.5e-40 138.7 1.9 2.4e-40 138.1 1.9 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF49737.1 - 1.9e-13 50.8 0.2 1.9e-13 50.8 0.2 2.4 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal KASH PF10541.9 OWF49737.1 - 0.0031 17.7 1.7 0.0086 16.3 1.7 1.7 1 0 0 1 1 1 1 Nuclear envelope localisation domain Tudor-knot PF11717.8 OWF49738.1 - 2.4e-07 30.5 1.7 1.8e-06 27.7 1.1 2.5 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 OWF49738.1 - 6.7e-07 28.9 0.3 2.8e-06 26.9 0.3 2.1 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain PHD PF00628.29 OWF49738.1 - 6.4e-06 26.0 9.8 1.8e-05 24.6 9.8 1.8 1 0 0 1 1 1 1 PHD-finger MBT PF02820.18 OWF49738.1 - 0.0016 18.7 0.2 0.0056 17.0 0.1 2.0 2 0 0 2 2 2 1 mbt repeat zf-C2H2 PF00096.26 OWF49738.1 - 0.037 14.5 0.7 0.17 12.4 0.7 2.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rad9_Rad53_bind PF08605.10 OWF49738.1 - 0.072 13.3 0.1 3.1 8.0 0.0 2.8 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding TUDOR_5 PF18359.1 OWF49738.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Ank_2 PF12796.7 OWF49739.1 - 1.1e-06 29.2 0.2 5.4e-05 23.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF49739.1 - 1.1e-05 25.4 1.2 0.35 11.6 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OWF49739.1 - 1.3e-05 25.4 0.1 0.0024 18.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF49739.1 - 5.1e-05 23.7 0.1 0.019 15.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF49739.1 - 0.024 15.1 2.2 0.28 11.7 0.1 3.2 4 0 0 4 4 4 0 Ankyrin repeat DUF2760 PF10816.8 OWF49739.1 - 0.053 13.4 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) C12orf66_like PF09404.10 OWF49740.1 - 1.7e-142 475.3 12.4 2.1e-142 475.1 12.4 1.0 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like Nse4-Nse3_bdg PF15412.6 OWF49740.1 - 0.01 15.9 0.1 15 5.7 0.0 3.5 3 0 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE UPF0242 PF06785.11 OWF49741.1 - 2.2 8.3 14.2 4.8 7.2 14.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-ZPR1 PF03367.13 OWF49742.1 - 0.00026 20.9 27.5 20 5.0 0.9 10.5 8 2 2 10 10 10 8 ZPR1 zinc-finger domain zf-C2H2_11 PF16622.5 OWF49742.1 - 0.018 14.8 40.8 25 4.8 0.2 11.2 10 0 0 10 10 10 0 zinc-finger C2H2-type RhoGAP-FF1 PF16512.5 OWF49743.1 - 1.1e-12 48.5 40.3 3.9 8.2 0.1 16.2 2 2 17 19 19 19 5 p190-A and -B Rho GAPs FF domain Protoglobin PF11563.8 OWF49743.1 - 8.4e-08 32.3 47.2 1.7 8.5 2.2 10.4 2 2 5 7 7 7 7 Protoglobin HTH_18 PF12833.7 OWF49743.1 - 0.0066 16.7 3.7 55 4.1 0.0 6.7 4 2 3 8 8 8 0 Helix-turn-helix domain AvrM_N PF18247.1 OWF49743.1 - 0.078 12.9 28.0 23 5.0 0.1 10.8 5 2 6 13 13 13 0 Flax-rust effector AvrM N-terminal domain FAM220 PF15487.6 OWF49743.1 - 0.32 10.6 18.4 15 5.1 0.1 7.2 3 3 5 10 10 10 0 FAM220 family A2M_BRD PF07703.14 OWF49744.1 - 5e-16 59.3 3.7 8.6e-16 58.6 1.9 2.3 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 OWF49744.1 - 7.3e-12 45.4 0.1 2.3e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 OWF49744.1 - 1e-11 45.1 0.0 4.8e-11 43.0 0.0 2.3 1 0 0 1 1 1 1 MG2 domain Big_1 PF02369.16 OWF49744.1 - 0.00073 19.5 0.6 0.00073 19.5 0.6 4.0 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 1) Gln-synt_N_2 PF16952.5 OWF49744.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain MG4 PF17789.1 OWF49744.1 - 0.17 12.1 1.4 23 5.2 0.0 3.6 3 0 0 3 3 3 0 Macroglobulin domain MG4 C1q PF00386.21 OWF49745.1 - 4.3e-19 69.0 0.3 1.2e-18 67.6 0.3 1.8 1 0 0 1 1 1 1 C1q domain betaPIX_CC PF16523.5 OWF49745.1 - 0.0017 18.2 4.4 0.0028 17.4 4.4 1.3 1 0 0 1 1 1 1 betaPIX coiled coil ZapB PF06005.12 OWF49745.1 - 0.0029 18.0 6.6 0.0083 16.6 6.6 1.7 1 1 0 1 1 1 1 Cell division protein ZapB NRBF2 PF08961.10 OWF49745.1 - 0.0069 16.0 4.1 0.0097 15.5 4.1 1.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator NICE-3 PF07406.11 OWF49745.1 - 0.0088 16.0 0.4 0.014 15.4 0.4 1.3 1 0 0 1 1 1 1 NICE-3 protein UPF0242 PF06785.11 OWF49745.1 - 0.022 14.9 3.8 0.031 14.4 3.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BclA_C PF18573.1 OWF49745.1 - 0.024 14.5 2.1 0.045 13.6 1.1 1.9 2 0 0 2 2 2 0 BclA C-terminal domain RasGAP_C PF03836.15 OWF49745.1 - 0.18 11.9 6.2 0.3 11.2 6.2 1.3 1 0 0 1 1 1 0 RasGAP C-terminus YabA PF06156.13 OWF49745.1 - 0.4 11.3 4.7 0.73 10.5 4.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Tup_N PF08581.10 OWF49745.1 - 0.51 10.7 6.5 0.92 9.9 6.5 1.4 1 0 0 1 1 1 0 Tup N-terminal PRKG1_interact PF15898.5 OWF49745.1 - 1.3 9.9 10.5 3.3 8.7 1.3 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF5094 PF17015.5 OWF49745.1 - 1.9 8.6 7.6 1.6 8.8 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) TIG PF01833.24 OWF49746.1 - 3.5e-89 293.0 88.7 3.7e-13 49.3 3.5 13.9 13 0 0 13 13 13 10 IPT/TIG domain G8 PF10162.9 OWF49746.1 - 2.6e-48 163.2 1.1 1.1e-29 103.0 0.2 3.0 2 0 0 2 2 2 2 G8 domain Beta_helix PF13229.6 OWF49746.1 - 2.6e-10 40.3 15.9 0.0024 17.8 10.1 5.6 2 2 1 4 4 4 3 Right handed beta helix region Insulin_TMD PF17870.1 OWF49746.1 - 0.055 13.5 1.7 0.18 11.9 1.7 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Arm_vescicular PF18770.1 OWF49748.1 - 0.0026 17.7 4.3 4.8 7.2 0.4 3.8 1 1 3 4 4 4 3 Armadillo tether-repeat of vescicular transport factor DUF5359 PF17313.2 OWF49748.1 - 0.13 12.3 0.4 4.8 7.2 0.1 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5359) DUF3320 PF11784.8 OWF49748.1 - 1.3 9.0 8.1 13 5.8 0.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3320) DNA_pol_A_exo1 PF01612.20 OWF49749.1 - 4.7e-32 111.1 0.4 9.5e-32 110.1 0.4 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HD_3 PF13023.6 OWF49749.1 - 0.016 15.2 0.7 0.034 14.1 0.7 1.5 1 0 0 1 1 1 0 HD domain SopE_GEF PF07487.13 OWF49749.1 - 0.43 10.7 3.3 3.7 7.6 0.1 3.2 2 2 1 3 3 3 0 SopE GEF domain AbiH PF14253.6 OWF49749.1 - 5.2 6.9 6.5 11 5.9 0.5 2.3 1 1 0 2 2 2 0 Bacteriophage abortive infection AbiH p450 PF00067.22 OWF49750.1 - 9.5e-106 354.3 0.1 1.2e-105 354.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_A_exo1 PF01612.20 OWF49751.1 - 1.7e-26 93.0 1.1 2.7e-26 92.4 1.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Lectin_C PF00059.21 OWF49752.1 - 2.3e-13 50.8 0.2 2.3e-13 50.8 0.2 2.3 2 1 0 3 3 3 1 Lectin C-type domain PAN_1 PF00024.26 OWF49752.1 - 0.00019 21.3 4.2 0.00019 21.3 4.2 1.8 2 0 0 2 2 2 1 PAN domain IgGFc_binding PF17517.2 OWF49753.1 - 2.3e-38 132.2 0.9 3.3e-38 131.6 0.9 1.3 1 0 0 1 1 1 1 IgGFc binding protein Lipase_GDSL_2 PF13472.6 OWF49755.1 - 6.9e-07 29.8 0.0 7.6e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF49755.1 - 0.069 13.1 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase mTERF PF02536.14 OWF49756.1 - 5.1e-17 61.8 4.5 6.3e-17 61.5 4.5 1.1 1 0 0 1 1 1 1 mTERF dUTPase_2 PF08761.11 OWF49756.1 - 0.1 12.8 0.4 0.31 11.2 0.0 2.0 2 1 0 2 2 2 0 dUTPase HTH_Mga PF08280.11 OWF49756.1 - 0.13 12.3 3.4 10 6.3 0.6 2.8 2 1 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain PDCD9 PF07147.12 OWF49757.1 - 0.027 13.7 0.2 2.3 7.3 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) APP_E2 PF12925.7 OWF49758.1 - 1.8e-48 164.8 19.9 1.8e-48 164.8 19.9 1.7 2 0 0 2 2 2 1 E2 domain of amyloid precursor protein APP_amyloid PF10515.9 OWF49758.1 - 3.5e-26 91.4 0.5 3.5e-26 91.4 0.5 2.4 2 0 0 2 2 2 1 Beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.7 OWF49758.1 - 7.5e-16 58.6 5.5 7.5e-16 58.6 5.5 2.3 2 0 0 2 2 2 1 Copper-binding of amyloid precursor, CuBD APP_N PF02177.16 OWF49758.1 - 3.2e-15 56.3 0.3 9.9e-15 54.7 0.3 1.9 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding Amnionless PF14828.6 OWF49758.1 - 0.0045 15.9 0.1 0.008 15.1 0.1 1.4 1 0 0 1 1 1 1 Amnionless TipAS PF07739.13 OWF49758.1 - 0.46 11.0 7.1 0.9 10.1 5.9 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF3106 PF11304.8 OWF49758.1 - 1.2 9.7 15.0 2.3 8.7 0.4 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3106) MFS_1 PF07690.16 OWF49759.1 - 4.2e-54 183.8 49.8 9.6e-53 179.3 39.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_2 PF03567.14 OWF49760.1 - 1.7e-15 57.6 1.9 6.5e-15 55.7 0.1 2.0 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF49761.1 - 9.4e-19 68.3 2.1 2.1e-18 67.2 0.1 2.1 2 0 0 2 2 2 1 Sulfotransferase family Head_binding PF09008.10 OWF49761.1 - 0.092 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Head binding Zona_pellucida PF00100.23 OWF49762.1 - 2.1e-07 31.0 3.7 2.5e-07 30.7 3.7 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain C2 PF00168.30 OWF49763.1 - 5.6e-17 61.9 0.0 2e-16 60.2 0.0 2.0 1 0 0 1 1 1 1 C2 domain SMP_C2CD2L PF18696.1 OWF49763.1 - 1.2e-09 38.1 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Synaptotagmin-like, mitochondrial and lipid-binding domain DNA_pol_A_exo1 PF01612.20 OWF49764.1 - 2.3e-13 50.2 0.0 7.5e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 3'-5' exonuclease PNPase PF03726.14 OWF49764.1 - 0.16 12.5 3.8 0.38 11.3 3.3 2.0 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain TatD_DNase PF01026.21 OWF49765.1 - 9.9e-17 61.2 0.0 1.2e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Radical_SAM_C PF16199.5 OWF49765.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Radical_SAM C-terminal domain SGL PF08450.12 OWF49766.1 - 0.00012 21.8 0.1 0.13 11.8 0.0 2.8 2 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF49766.1 - 0.0018 18.2 7.3 0.71 10.0 0.9 4.8 4 0 0 4 4 4 1 NHL repeat Phytase-like PF13449.6 OWF49766.1 - 0.0058 16.6 0.0 0.015 15.2 0.0 1.7 1 1 1 2 2 2 1 Esterase-like activity of phytase 7tm_1 PF00001.21 OWF49767.1 - 2.7e-14 53.1 9.1 3.9e-14 52.6 9.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ntox50 PF15542.6 OWF49768.1 - 0.18 12.6 5.8 12 6.7 0.4 2.9 1 1 2 3 3 3 0 Bacterial toxin 50 MIT_C PF16565.5 OWF49768.1 - 1.4 8.9 10.4 97 2.9 0.2 3.9 1 1 2 3 3 3 0 Phospholipase D-like domain at C-terminus of MIT ATP-grasp_4 PF13535.6 OWF49769.1 - 4.1e-11 42.7 0.0 9.7e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 OWF49769.1 - 3.7e-09 36.4 0.2 2.6e-08 33.7 0.2 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 OWF49769.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 OWF49769.1 - 0.0001 22.4 0.0 0.00032 20.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OWF49769.1 - 0.02 14.4 0.0 0.12 11.8 0.0 2.1 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_N PF18130.1 OWF49769.1 - 0.027 15.0 0.0 0.065 13.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp N-terminal domain FGAR-AT_N PF18076.1 OWF49770.1 - 0.1 12.6 0.0 32 4.5 0.0 3.4 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Chlam_OMP3 PF03503.13 OWF49770.1 - 2 8.8 12.7 0.84 10.0 0.3 5.7 5 0 0 5 5 5 0 Chlamydia cysteine-rich outer membrane protein 3 Bcl-2 PF00452.19 OWF49771.1 - 9.5e-25 87.2 0.1 1.7e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family zf-NF-X1 PF01422.17 OWF49772.1 - 0.12 12.5 3.3 0.31 11.1 3.3 1.8 1 0 0 1 1 1 0 NF-X1 type zinc finger EF-hand_1 PF00036.32 OWF49773.1 - 7.2e-15 53.4 5.4 3.1e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF49773.1 - 3.1e-10 40.3 1.1 6.8e-10 39.3 1.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF49773.1 - 6.4e-10 38.2 2.3 0.00013 21.6 1.2 2.7 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OWF49773.1 - 7.9e-10 37.8 3.0 0.00012 21.5 2.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF49773.1 - 4.3e-09 36.1 2.4 0.00067 19.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair DUF3471 PF11954.8 OWF49773.1 - 0.048 14.1 0.1 0.096 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) EF-hand_9 PF14658.6 OWF49773.1 - 0.11 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain YolD PF08863.10 OWF49773.1 - 1.2 9.3 5.2 2.2 8.4 0.4 2.4 1 1 1 2 2 2 0 YolD-like protein RRP36 PF06102.12 OWF49773.1 - 1.2 9.1 6.0 0.13 12.2 1.8 1.5 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 E1_dh PF00676.20 OWF49774.1 - 1.8e-113 378.4 0.1 2.2e-113 378.1 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OWF49774.1 - 0.00034 20.4 0.4 0.00064 19.5 0.4 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OWF49774.1 - 0.00096 18.4 0.0 0.0023 17.2 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase MobL PF18555.1 OWF49774.1 - 0.01 15.1 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 MobL relaxases Erythro_esteras PF05139.14 OWF49774.1 - 0.019 14.8 0.2 0.039 13.8 0.0 1.5 2 0 0 2 2 2 0 Erythromycin esterase EGF_3 PF12947.7 OWF49775.1 - 0.00024 21.2 9.6 0.11 12.7 2.5 2.6 2 0 0 2 2 2 2 EGF domain EGF_CA PF07645.15 OWF49775.1 - 0.00041 20.5 11.2 0.06 13.6 2.0 3.0 2 0 0 2 2 2 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF49775.1 - 0.0033 17.7 11.9 0.015 15.5 1.8 2.5 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF49775.1 - 0.0095 15.8 10.3 0.046 13.6 0.8 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like hEGF PF12661.7 OWF49775.1 - 0.032 14.9 16.2 0.12 13.1 3.4 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF EGF PF00008.27 OWF49775.1 - 0.048 14.0 13.7 1.4 9.3 1.9 2.7 2 0 0 2 2 2 0 EGF-like domain zf-H2C2_2 PF13465.6 OWF49776.1 - 1.5e-25 88.5 50.8 1.7e-05 25.0 0.6 7.9 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.26 OWF49776.1 - 2.4e-24 84.4 56.1 6e-06 26.4 3.3 8.4 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF49776.1 - 4.2e-18 64.5 49.8 0.00043 20.9 2.0 8.3 7 1 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 OWF49776.1 - 8.3e-05 22.8 33.1 0.36 11.3 1.0 7.0 6 0 0 6 6 6 4 Zinc-finger of C2H2 type SET PF00856.28 OWF49776.1 - 0.0038 17.6 1.1 0.012 16.1 0.0 2.4 3 0 0 3 3 3 1 SET domain zf-C2H2_jaz PF12171.8 OWF49776.1 - 0.008 16.4 36.2 0.01 16.1 0.3 6.7 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 OWF49776.1 - 0.031 14.4 18.6 0.034 14.3 1.3 4.9 4 1 1 5 5 5 0 Zinc ribbon domain zf-CHCC PF10276.9 OWF49776.1 - 0.059 13.4 0.1 0.059 13.4 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger domain HLH PF00010.26 OWF49776.1 - 0.14 12.2 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain zinc_ribbon_9 PF14369.6 OWF49776.1 - 0.15 12.4 9.5 55 4.1 0.0 5.6 5 1 1 6 6 6 0 zinc-ribbon zf-C2H2_6 PF13912.6 OWF49776.1 - 0.44 10.6 40.1 0.03 14.3 2.7 7.2 7 0 0 7 7 7 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 OWF49776.1 - 0.91 10.3 26.8 0.96 10.2 1.9 4.8 2 1 2 5 5 4 0 zinc-ribbon family FYVE PF01363.21 OWF49776.1 - 5.8 7.1 33.5 4.5 7.5 0.4 5.3 2 1 2 4 4 3 0 FYVE zinc finger zf_C2H2_10 PF18414.1 OWF49776.1 - 9.9 5.8 8.4 1.9 8.1 1.5 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger Octopine_DH PF02317.17 OWF49777.1 - 6.4e-31 107.5 0.0 8.9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 OWF49777.1 - 0.00095 19.7 0.1 0.0023 18.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 OWF49777.1 - 0.01 15.9 0.2 0.037 14.0 0.1 2.0 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 OWF49777.1 - 0.057 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.17 OWF49777.1 - 0.089 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Bac_export_2 PF01312.19 OWF49777.1 - 0.097 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family ParBc PF02195.18 OWF49778.1 - 1.9e-06 28.1 0.0 6.8e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 ParB-like nuclease domain ParBc PF02195.18 OWF49780.1 - 2.1e-06 27.9 0.0 7.5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 ParB-like nuclease domain ParBc PF02195.18 OWF49781.1 - 4.2e-05 23.7 0.0 0.00016 21.9 0.0 1.9 2 0 0 2 2 2 1 ParB-like nuclease domain Sgf11_N PF18519.1 OWF49782.1 - 0.027 14.0 36.0 0.6 9.7 2.9 5.2 2 1 3 5 5 5 0 SAGA-associated factor 11 N-terminal domain DUF384 PF04064.13 OWF49782.1 - 2.3 8.2 8.2 12 5.8 0.1 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF384) MFS_1 PF07690.16 OWF49784.1 - 9.2e-12 44.5 9.4 1.4e-11 44.0 9.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF49785.1 - 2.6e-20 72.7 13.9 2.6e-20 72.7 13.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SIR2 PF02146.17 OWF49786.1 - 1.4e-25 90.2 1.1 1.2e-24 87.3 1.1 2.3 1 1 0 1 1 1 1 Sir2 family SmAKAP PF15127.6 OWF49786.1 - 0.067 14.4 0.1 0.47 11.7 0.0 2.2 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein MRP-S34 PF16053.5 OWF49787.1 - 2.2e-23 82.3 0.1 2.7e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Toxin_R_bind_C PF07951.12 OWF49787.1 - 0.084 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Arf PF00025.21 OWF49788.1 - 7e-54 181.9 0.0 7.9e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF49788.1 - 2.7e-16 59.8 0.0 3.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF49788.1 - 9e-15 54.6 0.0 9.4e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF49788.1 - 1.9e-10 40.5 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OWF49788.1 - 1.6e-07 30.8 1.2 4.5e-05 22.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OWF49788.1 - 1.4e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF49788.1 - 0.0035 16.9 0.0 0.021 14.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain P66_CC PF16563.5 OWF49788.1 - 0.02 14.5 0.4 0.11 12.2 0.5 2.0 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 RF-1 PF00472.20 OWF49789.1 - 4.1e-20 71.9 0.6 6.4e-20 71.2 0.6 1.2 1 0 0 1 1 1 1 RF-1 domain Pkinase PF00069.25 OWF49790.1 - 9.3e-68 228.4 0.0 2.2e-67 227.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49790.1 - 2.9e-38 131.6 0.0 4.8e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 OWF49790.1 - 6.6e-35 118.8 23.9 3.3e-18 65.3 11.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 OWF49790.1 - 5.9e-25 87.5 0.0 1.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 OWF49790.1 - 4.7e-07 30.4 1.5 1e-06 29.3 1.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 OWF49790.1 - 3.3e-05 24.1 18.4 0.011 16.1 4.4 2.5 2 0 0 2 2 2 2 C1 domain FTA2 PF13095.6 OWF49790.1 - 0.014 15.0 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OWF49790.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OWF49790.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF49790.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like PHD PF00628.29 OWF49790.1 - 0.11 12.4 18.8 1.2 9.1 6.6 2.6 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 OWF49790.1 - 0.93 9.4 17.5 2.2 8.2 7.4 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FYVE_2 PF02318.16 OWF49790.1 - 1.3 9.2 9.5 3 8.1 1.0 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Pkinase_Tyr PF07714.17 OWF49791.1 - 1.1e-34 119.9 0.0 1.7e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF49791.1 - 5.3e-32 111.2 0.0 8.3e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 OWF49791.1 - 7.2e-12 44.6 0.7 1.5e-11 43.6 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 OWF49791.1 - 3.2e-11 44.1 9.0 3.2e-11 44.1 9.0 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 OWF49791.1 - 0.00011 21.2 0.9 0.00012 21.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OWF49791.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Mito_carr PF00153.27 OWF49792.1 - 1.1e-61 204.8 4.0 4.7e-20 71.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CHU_C PF13585.6 OWF49793.1 - 0.027 14.5 8.8 8.4 6.5 0.1 4.5 1 1 3 5 5 5 0 C-terminal domain of CHU protein family NTS PF15447.6 OWF49793.1 - 0.029 14.8 0.1 26 5.4 0.0 4.3 5 0 0 5 5 5 0 N-terminal segments of PfEMP1 UPF0253 PF06786.12 OWF49793.1 - 0.043 14.1 1.0 44 4.5 0.1 3.7 1 1 2 4 4 4 0 Uncharacterised protein family (UPF0253) Cmc1 PF08583.10 OWF49793.1 - 0.077 13.0 0.5 3.5 7.7 0.1 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF5128 PF17170.4 OWF49793.1 - 1.4 8.0 12.3 6.9 5.7 0.1 4.0 1 1 2 4 4 4 0 6-bladed beta-propeller Gtr1_RagA PF04670.12 OWF49793.1 - 1.5 8.1 8.6 3.3 7.0 0.1 3.3 1 1 0 3 3 3 0 Gtr1/RagA G protein conserved region DUF848 PF05852.11 OWF49793.1 - 3.2 7.8 8.6 21 5.2 0.0 4.8 2 1 3 5 5 5 0 Gammaherpesvirus protein of unknown function (DUF848) 7tm_1 PF00001.21 OWF49794.1 - 7.2e-14 51.7 22.9 9e-14 51.4 22.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF49794.1 - 1.2e-12 47.8 25.3 1.6e-12 47.3 25.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF49794.1 - 1.2e-08 34.6 22.7 1.2e-07 31.4 22.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF49794.1 - 0.0029 17.3 28.6 0.029 14.0 28.5 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx YqzH PF14164.6 OWF49794.1 - 0.099 12.7 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 YqzH-like protein DUF4407 PF14362.6 OWF49794.1 - 2.4 7.4 4.9 5.3 6.3 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-B_box PF00643.24 OWF49795.1 - 1.1e-09 38.3 8.6 1.1e-09 38.3 8.6 2.0 2 0 0 2 2 2 1 B-box zinc finger NHL PF01436.21 OWF49795.1 - 0.00089 19.2 7.6 0.026 14.5 1.5 4.1 4 0 0 4 4 4 1 NHL repeat IFT57 PF10498.9 OWF49795.1 - 0.0023 17.0 5.7 0.0023 17.0 5.7 1.7 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Phage_Mu_Gam PF07352.12 OWF49795.1 - 0.0045 16.9 0.0 0.59 10.0 0.0 2.3 1 1 1 2 2 2 2 Bacteriophage Mu Gam like protein DUF3430 PF11912.8 OWF49795.1 - 0.039 14.0 0.3 0.088 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Laminin_I PF06008.14 OWF49795.1 - 0.046 13.4 1.3 0.071 12.8 1.3 1.2 1 0 0 1 1 1 0 Laminin Domain I Prominin PF05478.11 OWF49795.1 - 0.058 11.4 2.5 0.081 10.9 2.5 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 OWF49795.1 - 0.38 10.8 5.6 0.42 10.7 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cor1 PF04803.12 OWF49795.1 - 0.48 10.6 4.0 0.91 9.7 4.0 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Ras PF00071.22 OWF49796.1 - 8.6e-60 201.0 0.2 1.1e-59 200.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF49796.1 - 1.1e-33 116.0 0.2 2.1e-33 115.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF49796.1 - 1.8e-14 53.6 0.1 2.3e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF49796.1 - 2.9e-05 23.5 0.1 3.8e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF49796.1 - 0.00034 20.7 0.0 0.00065 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF49796.1 - 0.00048 19.6 0.0 0.0008 18.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OWF49796.1 - 0.00051 19.8 0.0 0.00088 19.0 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OWF49796.1 - 0.0043 17.0 0.2 0.23 11.4 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OWF49796.1 - 0.012 15.2 0.5 0.032 13.8 0.1 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OWF49796.1 - 0.029 14.6 0.1 0.21 11.9 0.0 2.3 1 1 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 OWF49796.1 - 0.031 13.8 0.2 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_24 PF13479.6 OWF49796.1 - 0.044 13.5 0.2 0.082 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OWF49796.1 - 0.045 13.0 0.2 0.11 11.8 0.2 1.6 1 1 0 1 1 1 0 Septin AAA_16 PF13191.6 OWF49796.1 - 0.094 13.1 0.1 0.15 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OWF49796.1 - 0.11 12.0 0.1 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 OWF49796.1 - 0.2 11.4 0.6 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain LuxT_C PF18285.1 OWF49797.1 - 0.034 14.7 0.1 0.074 13.6 0.1 1.6 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain AbiEi_1 PF09407.10 OWF49797.1 - 0.034 14.5 0.4 0.66 10.3 0.0 2.4 3 0 0 3 3 3 0 AbiEi antitoxin C-terminal domain RRM_1 PF00076.22 OWF49798.1 - 2.1e-12 46.7 0.0 3.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OWF49798.1 - 6.3e-06 26.6 31.7 6.3e-06 26.6 31.7 4.4 2 2 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 FYTT PF07078.11 OWF49798.1 - 0.0017 17.7 4.9 0.0027 17.1 4.9 1.3 1 0 0 1 1 1 1 Forty-two-three protein RRM_occluded PF16842.5 OWF49798.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RGS_DHEX PF18148.1 OWF49799.1 - 2.5e-30 104.5 3.3 2.5e-30 104.5 3.3 2.7 3 0 0 3 3 3 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 OWF49799.1 - 1.3e-29 102.9 5.1 1.3e-29 102.9 5.1 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 OWF49799.1 - 4.7e-10 39.4 0.0 1.4e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 OWF49799.1 - 6.2e-08 32.5 0.5 6.2e-08 32.5 0.5 2.2 2 0 0 2 2 2 1 GGL domain Isochorismatase PF00857.20 OWF49799.1 - 0.084 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Isochorismatase family DEK_C PF08766.11 OWF49799.1 - 0.71 9.9 2.7 29 4.7 0.0 3.1 3 0 0 3 3 3 0 DEK C terminal domain Vac_ImportDeg PF09783.9 OWF49800.1 - 1.3e-62 210.4 4.9 1.5e-62 210.2 4.9 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein ATP12 PF07542.11 OWF49801.1 - 2e-37 128.1 0.3 3.3e-37 127.4 0.3 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein MT-A70 PF05063.14 OWF49801.1 - 0.05 13.5 0.3 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 MT-A70 LRR_9 PF14580.6 OWF49802.1 - 4e-18 65.5 6.0 1.6e-17 63.5 2.2 2.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OWF49802.1 - 9.1e-11 41.8 25.5 6.3e-06 26.4 3.2 4.5 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF49802.1 - 0.0011 18.6 4.2 0.0011 18.6 4.2 3.9 2 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 OWF49802.1 - 5.3 8.0 7.2 1.6e+02 3.5 0.0 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat DUF3632 PF12311.8 OWF49802.1 - 5.9 7.3 9.2 0.21 12.0 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3632) VHS PF00790.19 OWF49803.1 - 8.9e-42 142.3 0.1 3.2e-41 140.5 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 OWF49803.1 - 1.2e-22 80.0 3.3 1.2e-22 80.0 3.3 2.2 3 0 0 3 3 3 1 GAT domain ENTH PF01417.20 OWF49803.1 - 0.00032 20.7 0.0 0.00077 19.5 0.0 1.7 1 0 0 1 1 1 1 ENTH domain ZapB PF06005.12 OWF49803.1 - 0.028 14.9 0.3 0.028 14.9 0.3 2.9 4 0 0 4 4 4 0 Cell division protein ZapB NPA PF16469.5 OWF49803.1 - 0.82 10.3 3.2 0.56 10.8 0.7 2.0 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 Forkhead_N PF08430.12 OWF49803.1 - 3.2 8.4 21.3 1.8 9.2 14.7 2.5 2 0 0 2 2 2 0 Forkhead N-terminal region USP8_dimer PF08969.11 OWF49804.1 - 1.6e-20 73.4 0.0 1.6e-20 73.4 0.0 2.1 2 1 0 3 3 3 1 USP8 dimerisation domain JAB PF01398.21 OWF49804.1 - 7.1e-17 61.5 1.5 1.4e-16 60.5 0.0 2.1 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MIT PF04212.18 OWF49804.1 - 0.00012 22.0 1.2 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Prok-JAB PF14464.6 OWF49804.1 - 0.00014 21.6 0.4 0.00037 20.2 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain AP1AR PF15745.5 OWF49804.1 - 0.22 11.1 12.6 0.33 10.5 12.6 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein OmpH PF03938.14 OWF49804.1 - 0.52 10.6 17.7 0.87 9.9 17.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RhoGAP PF00620.27 OWF49805.1 - 3e-41 140.8 0.0 9.9e-41 139.1 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain ADH_zinc_N PF00107.26 OWF49806.1 - 2.1e-26 92.4 0.4 5e-26 91.2 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF49806.1 - 4.7e-25 87.6 3.9 8.9e-25 86.7 3.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OWF49806.1 - 2.5e-10 40.2 0.2 3.8e-10 39.6 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OWF49806.1 - 1.4e-07 32.6 0.1 2.3e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OWF49806.1 - 0.00011 21.5 0.3 0.0002 20.8 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 OWF49806.1 - 0.00021 21.9 0.8 0.00072 20.2 0.1 2.3 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 OWF49806.1 - 0.00075 19.0 0.3 0.0013 18.2 0.3 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.19 OWF49806.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.14 OWF49806.1 - 0.01 15.4 0.6 0.29 10.7 0.6 2.2 1 1 0 1 1 1 0 Methyltransferase small domain ADH_N_2 PF16884.5 OWF49806.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 OWF49806.1 - 0.069 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF43 PF01861.16 OWF49806.1 - 0.15 11.3 0.3 0.27 10.4 0.3 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Nuc_recep-AF1 PF11825.8 OWF49807.1 - 0.34 11.0 4.9 1.6 8.8 0.2 3.0 1 1 1 2 2 2 0 Nuclear/hormone receptor activator site AF-1 CRM1_repeat_3 PF18787.1 OWF49807.1 - 3.5 7.8 11.2 6.7 6.9 0.4 4.4 1 1 4 5 5 5 0 CRM1 / Exportin repeat 3 zf-CCHC_5 PF14787.6 OWF49808.1 - 1.7e-06 27.6 47.9 0.12 12.1 1.5 9.3 6 2 6 12 12 12 9 GAG-polyprotein viral zinc-finger VCX_VCY PF15231.6 OWF49808.1 - 0.0004 21.1 0.2 16 6.2 0.0 4.4 1 1 4 5 5 5 1 Variable charge X/Y family PMG PF05287.12 OWF49808.1 - 0.02 14.9 3.4 0.65 10.0 1.0 2.4 1 1 1 2 2 2 0 PMG protein DUF2197 PF09963.9 OWF49808.1 - 1.1 9.6 37.9 32 4.9 2.5 8.2 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2197) Peptidase_C2 PF00648.21 OWF49809.1 - 7.5e-103 343.6 0.0 1.3e-102 342.8 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF49809.1 - 6e-34 117.3 1.1 2.3e-33 115.4 0.0 2.6 3 0 0 3 3 3 1 Calpain large subunit, domain III zf-CCHC_5 PF14787.6 OWF49809.1 - 1.4e-07 31.1 68.1 0.21 11.4 4.2 12.2 9 3 4 13 13 13 7 GAG-polyprotein viral zinc-finger EF-hand_8 PF13833.6 OWF49809.1 - 2.1e-06 27.5 0.0 2.4e-05 24.1 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF49809.1 - 3.8e-06 26.4 0.0 0.16 11.9 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OWF49809.1 - 9.7e-06 24.8 0.0 0.28 10.8 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF49809.1 - 7.5e-05 23.1 0.1 0.21 12.1 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair VCX_VCY PF15231.6 OWF49809.1 - 0.033 14.9 0.6 96 3.7 0.0 4.5 1 1 4 5 5 5 0 Variable charge X/Y family p450 PF00067.22 OWF49810.1 - 1.2e-113 380.4 0.0 1.4e-113 380.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.6 OWF49811.1 - 0.00028 21.2 0.0 0.095 13.1 0.0 3.4 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 OWF49811.1 - 0.013 15.6 9.3 0.12 12.4 0.2 4.8 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OWF49811.1 - 0.2 12.0 3.5 12 6.5 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat Tti2 PF10521.9 OWF49811.1 - 0.34 10.4 4.9 4.6 6.7 0.2 3.0 3 0 0 3 3 3 0 Tti2 family TAN PF11640.8 OWF49811.1 - 1.3 9.2 5.2 2.1 8.5 0.1 3.9 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair Peptidase_M16 PF00675.20 OWF49812.1 - 1.6e-20 73.6 0.0 3e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OWF49812.1 - 5.6e-11 42.8 0.0 8.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain MT-A70 PF05063.14 OWF49813.1 - 2.7e-56 190.2 0.0 4e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 RNA_polI_A34 PF08208.11 OWF49813.1 - 0.012 15.7 5.2 0.02 15.0 5.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CTP_transf_like PF01467.26 OWF49814.1 - 2e-46 157.7 0.1 6e-30 104.3 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OWF49814.1 - 0.003 17.5 0.8 0.32 10.9 0.2 3.1 3 0 0 3 3 3 1 FAD synthetase SOCS_box PF07525.16 OWF49816.1 - 0.022 15.1 0.3 0.022 15.1 0.3 2.6 3 0 0 3 3 3 0 SOCS box zf-B_box PF00643.24 OWF49817.1 - 2.5e-06 27.5 0.3 6.7e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 B-box zinc finger NHL PF01436.21 OWF49817.1 - 0.06 13.4 0.7 0.44 10.7 0.0 2.7 2 0 0 2 2 2 0 NHL repeat Spc7 PF08317.11 OWF49817.1 - 0.077 11.9 6.8 0.13 11.2 6.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 OWF49817.1 - 0.13 12.5 5.4 2.2 8.6 2.3 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 OWF49817.1 - 1.8 7.9 5.2 6.2 6.1 0.5 2.1 2 0 0 2 2 2 0 FAM76 protein SKA2 PF16740.5 OWF49817.1 - 2.1 8.1 8.7 3.7 7.4 4.6 2.7 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1477 PF07346.11 OWF49818.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) TENA_THI-4 PF03070.16 OWF49819.1 - 5.3e-08 32.9 0.8 8.1e-08 32.3 0.8 1.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family RIBIOP_C PF04950.12 OWF49820.1 - 2.9e-90 302.7 0.1 2.9e-90 302.7 0.1 2.7 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OWF49820.1 - 9.3e-29 99.4 0.0 5.5e-28 96.9 0.0 2.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 OWF49820.1 - 1.1e-06 28.3 1.7 0.00044 19.9 0.0 3.4 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF49820.1 - 0.0013 18.8 0.1 0.024 14.7 0.1 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OWF49820.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OWF49820.1 - 0.035 14.5 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OWF49820.1 - 0.038 14.4 0.6 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OWF49820.1 - 0.038 14.1 0.2 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OWF49820.1 - 0.041 14.2 0.3 0.63 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OWF49820.1 - 0.56 10.7 0.0 0.56 10.7 0.0 4.2 4 1 0 4 4 4 0 ABC transporter 3HCDH_N PF02737.18 OWF49822.1 - 1.1e-62 211.2 1.8 1.5e-62 210.7 1.8 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OWF49822.1 - 9.3e-25 87.1 0.0 2.7e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain F420_oxidored PF03807.17 OWF49822.1 - 1.7e-05 25.3 3.4 7.8e-05 23.2 3.4 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 OWF49822.1 - 7.4e-05 22.0 1.0 9.8e-05 21.6 1.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 OWF49822.1 - 0.00014 21.5 1.0 0.00032 20.3 0.9 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 OWF49822.1 - 0.00015 21.9 2.7 0.00089 19.5 2.7 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 OWF49822.1 - 0.0003 20.1 0.3 0.00042 19.6 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF49822.1 - 0.00044 20.8 0.1 0.0011 19.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 OWF49822.1 - 0.00046 20.2 3.6 0.00068 19.6 2.1 2.1 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 OWF49822.1 - 0.00049 20.4 2.0 0.0011 19.2 1.5 1.9 2 0 0 2 2 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OWF49822.1 - 0.00076 19.9 1.4 0.0017 18.8 1.4 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 OWF49822.1 - 0.0013 18.1 3.3 0.0023 17.2 3.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OWF49822.1 - 0.0017 18.6 1.4 0.0041 17.4 1.4 1.8 1 1 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 OWF49822.1 - 0.004 16.4 0.3 0.0067 15.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain XdhC_C PF13478.6 OWF49822.1 - 0.0056 17.2 0.2 0.0099 16.4 0.2 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain HI0933_like PF03486.14 OWF49822.1 - 0.018 13.7 0.5 0.03 13.1 0.5 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 OWF49822.1 - 0.025 14.2 0.2 0.036 13.6 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DXP_synthase_N PF13292.6 OWF49822.1 - 0.044 13.0 1.1 0.069 12.3 1.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase 2-Hacid_dh_C PF02826.19 OWF49822.1 - 0.046 13.1 0.2 0.088 12.2 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OWF49822.1 - 0.11 11.9 0.4 0.17 11.4 0.4 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 OWF49822.1 - 0.14 12.4 0.2 0.32 11.2 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Phosphodiest PF01663.22 OWF49823.1 - 3.6e-70 237.3 1.5 4.2e-70 237.1 1.5 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF49823.1 - 3.3e-12 46.4 0.0 7.7e-06 25.5 0.0 2.4 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 OWF49823.1 - 1e-07 31.6 0.2 7.5e-07 28.8 0.3 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily Plk4_PB1 PF18190.1 OWF49823.1 - 0.13 12.4 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 SH2 PF00017.24 OWF49824.1 - 2.8e-35 120.3 0.3 6.3e-17 61.5 0.1 3.2 3 0 0 3 3 3 2 SH2 domain RasGAP PF00616.19 OWF49824.1 - 6.8e-28 97.8 2.0 1.8e-19 70.3 0.1 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 OWF49824.1 - 1.5e-14 54.4 0.5 4.7e-14 52.8 0.2 2.0 2 0 0 2 2 2 1 PH domain C2 PF00168.30 OWF49824.1 - 2.2e-11 43.9 0.1 5e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 OWF49824.1 - 7.1e-07 28.7 0.2 1.9e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OWF49824.1 - 0.00019 21.2 0.1 0.0005 19.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF49824.1 - 0.0003 20.4 0.0 0.00071 19.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH2_2 PF14633.6 OWF49824.1 - 0.00075 19.0 0.0 0.1 12.0 0.0 2.6 2 0 0 2 2 2 1 SH2 domain Gly_transf_sug PF04488.15 OWF49825.1 - 1.1e-17 64.5 0.0 2.5e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OWF49825.1 - 1.9e-05 24.1 1.8 0.14 11.4 1.5 2.2 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Glyco_transf_21 PF13506.6 OWF49826.1 - 4.5e-40 136.9 0.0 5.7e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OWF49826.1 - 8.3e-12 45.5 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OWF49826.1 - 1.8e-09 37.8 2.4 3e-09 37.1 2.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Treslin_N PF15292.6 OWF49827.1 - 3.6e-55 187.7 23.2 2.4e-52 178.4 19.6 3.2 3 0 0 3 3 3 3 Treslin N-terminus DUF4495 PF14906.6 OWF49828.1 - 1e-108 363.2 4.5 2.9e-108 361.7 4.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4495) TAP42 PF04177.12 OWF49828.1 - 0.047 12.8 0.3 0.08 12.1 0.3 1.3 1 0 0 1 1 1 0 TAP42-like family Phage_RpbA PF10789.9 OWF49828.1 - 0.2 11.8 0.6 2 8.5 1.1 2.4 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA WD40 PF00400.32 OWF49829.1 - 5.2e-37 125.2 21.8 9.6e-08 32.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF49829.1 - 3.1e-14 53.0 0.0 0.14 12.5 0.0 5.4 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF49829.1 - 4.3e-07 29.6 0.0 0.12 11.7 0.0 4.7 1 1 3 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 OWF49829.1 - 9.1e-05 21.6 0.4 2.1 7.2 0.1 3.6 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Mito_carr PF00153.27 OWF49830.1 - 1.3e-18 66.6 0.5 5.9e-12 45.3 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein Arrestin_C PF02752.22 OWF49831.1 - 3.5e-24 85.8 0.1 3.6e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF49831.1 - 2.1e-23 83.0 0.3 1.4e-22 80.3 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CARDB PF07705.11 OWF49831.1 - 0.081 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 CARDB GalKase_gal_bdg PF10509.9 OWF49832.1 - 2.4e-23 81.4 0.1 4.4e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OWF49832.1 - 3.3e-13 49.7 1.6 7.8e-13 48.5 1.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OWF49832.1 - 5.4e-11 42.7 0.0 1.6e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Pkinase PF00069.25 OWF49833.1 - 4.7e-71 239.2 0.0 5.6e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF49833.1 - 1e-30 106.9 0.0 1.3e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF49833.1 - 4.8e-08 32.7 0.0 9.5e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF49833.1 - 0.0041 16.5 0.1 0.0083 15.5 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2805 PF10985.8 OWF49833.1 - 0.03 14.7 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) bZIP_2 PF07716.15 OWF49834.1 - 4.4e-23 81.1 25.0 7.8e-15 54.7 6.7 2.7 3 0 0 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 OWF49834.1 - 1.2e-12 47.7 18.7 2.2e-07 30.9 8.7 2.4 2 0 0 2 2 2 2 bZIP transcription factor Baculo_p24 PF05073.12 OWF49834.1 - 0.19 11.5 0.2 0.34 10.7 0.2 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein bZIP_Maf PF03131.17 OWF49834.1 - 0.64 10.6 18.0 0.5 10.9 6.7 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 OWF49834.1 - 4.5 6.6 8.6 3.2 7.1 4.2 2.1 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M ATP-synt_B PF00430.18 OWF49835.1 - 0.27 11.3 6.0 0.62 10.2 6.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Sec6 PF06046.13 OWF49835.1 - 0.35 9.2 5.2 0.5 8.7 5.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 CABIT PF12736.7 OWF49836.1 - 3.8e-24 85.5 0.0 9.8e-24 84.1 0.0 1.7 1 1 0 1 1 1 1 Cell-cycle sustaining, positive selection, Rrp44_S1 PF17215.3 OWF49836.1 - 0.16 11.9 0.2 0.53 10.3 0.2 1.8 1 0 0 1 1 1 0 S1 domain CAP PF00188.26 OWF49837.1 - 6.9e-14 52.8 1.6 6.9e-14 52.8 1.6 4.0 4 1 0 4 4 4 1 Cysteine-rich secretory protein family ShK PF01549.24 OWF49837.1 - 6.5e-08 33.0 26.3 3.4e-05 24.3 6.7 3.4 4 0 0 4 4 4 2 ShK domain-like Ependymin PF00811.18 OWF49838.1 - 4.8e-14 52.7 1.3 5e-14 52.7 0.2 1.5 2 0 0 2 2 2 1 Ependymin ELFV_dehydrog_N PF02812.18 OWF49839.1 - 2.2e-59 199.0 0.0 4.2e-59 198.1 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 OWF49839.1 - 1.6e-48 165.6 0.2 1.1e-45 156.3 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L1 PF00687.21 OWF49840.1 - 2e-14 53.8 0.1 2.3e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Exo_endo_phos PF03372.23 OWF49841.1 - 5.4e-23 81.7 0.1 5.8e-22 78.3 0.1 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TMEM72 PF16054.5 OWF49842.1 - 3e-35 121.5 5.4 3.7e-35 121.3 5.4 1.0 1 0 0 1 1 1 1 Transmembrane protein family 72 Cg6151-P PF10233.9 OWF49842.1 - 0.00061 20.1 11.0 0.062 13.6 11.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 OWF49842.1 - 0.0045 17.0 4.3 0.055 13.5 0.0 2.2 2 0 0 2 2 2 1 COPI associated protein DUF308 PF03729.13 OWF49842.1 - 0.0049 17.2 0.0 0.0049 17.2 0.0 2.4 3 0 0 3 3 3 1 Short repeat of unknown function (DUF308) OSTMP1 PF09777.9 OWF49842.1 - 0.039 13.4 0.2 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3719 PF12516.8 OWF49843.1 - 1.1e-14 53.8 0.1 2.8e-12 46.2 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3719) Glyco_hydro_72 PF03198.14 OWF49844.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase BTB PF00651.31 OWF49845.1 - 1.1e-21 77.1 0.0 1.9e-14 53.8 0.0 3.4 2 1 0 2 2 2 2 BTB/POZ domain DUF4562 PF15123.6 OWF49846.1 - 4.8e-35 120.0 0.1 7.2e-35 119.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) Dpy-30 PF05186.13 OWF49847.1 - 1.3e-13 50.4 0.1 1.8e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif Membralin PF09746.9 OWF49847.1 - 0.45 9.5 7.5 0.57 9.2 7.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein Hid1 PF12722.7 OWF49847.1 - 6.8 4.7 16.8 8.5 4.4 16.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 OWF49848.1 - 1.7e-71 240.7 0.0 1.2e-70 237.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 OWF49848.1 - 2.7e-38 129.9 0.0 1.5e-19 69.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OWF49848.1 - 6.8e-38 130.4 0.0 1.7e-36 125.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PKcGMP_CC PF16808.5 OWF49848.1 - 4.5e-09 36.0 11.1 8.6e-09 35.1 11.1 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Kinase-like PF14531.6 OWF49848.1 - 7.7e-05 22.1 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF641 PF04859.12 OWF49848.1 - 0.0066 16.8 1.6 0.015 15.6 1.0 1.8 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) Pkinase_C PF00433.24 OWF49848.1 - 0.036 14.8 2.7 0.35 11.6 2.1 2.4 2 0 0 2 2 2 0 Protein kinase C terminal domain APH PF01636.23 OWF49848.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family P4Ha_N PF08336.11 OWF49848.1 - 0.054 13.5 0.4 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spc29 PF17082.5 OWF49848.1 - 0.069 13.0 0.8 0.15 11.9 0.8 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 DHR10 PF18595.1 OWF49848.1 - 0.34 11.0 5.7 0.58 10.2 3.1 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Phage_HK97_TLTM PF06120.11 OWF49848.1 - 3.3 6.8 6.4 0.3 10.2 1.7 1.7 2 0 0 2 2 2 0 Tail length tape measure protein Claudin_2 PF13903.6 OWF49849.1 - 1.4e-05 25.0 1.1 1.7e-05 24.7 1.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF49849.1 - 0.011 15.6 1.8 0.015 15.2 1.8 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family I-set PF07679.16 OWF49850.1 - 1e-15 57.6 1.8 0.00023 21.2 0.0 5.1 4 2 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF49850.1 - 2.8e-11 43.9 4.6 0.003 18.1 0.2 4.2 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 OWF49850.1 - 2.2e-07 31.0 0.6 0.85 9.8 0.1 3.9 3 2 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 OWF49850.1 - 0.0014 18.8 3.7 0.14 12.4 0.4 3.8 3 2 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 OWF49850.1 - 0.0083 16.4 4.2 0.28 11.6 0.1 4.0 3 2 1 4 4 4 1 Immunoglobulin domain TPM_phosphatase PF04536.14 OWF49851.1 - 1.2e-07 31.9 0.5 16 5.6 0.0 7.1 2 1 4 7 7 7 2 TPM domain DUF5450 PF17529.2 OWF49851.1 - 3.7e-05 23.9 5.1 27 4.9 0.0 6.2 2 1 3 6 6 6 1 Family of unknown function (DUF5450) TAFH PF07531.14 OWF49851.1 - 0.0054 16.8 15.5 22 5.2 0.0 9.0 4 2 8 12 12 12 1 NHR1 homology to TAF AMH_N PF04709.12 OWF49851.1 - 0.0098 14.8 2.5 0.0098 14.8 2.5 2.9 1 1 1 3 3 3 1 Anti-Mullerian hormone, N terminal region DUF4389 PF14333.6 OWF49851.1 - 0.085 12.8 3.5 26 4.8 0.0 5.1 4 1 1 6 6 6 0 Domain of unknown function (DUF4389) Ephrin_rec_like PF07699.13 OWF49853.1 - 5.9e-26 90.0 54.8 2.2e-12 46.5 7.4 6.5 4 2 2 6 6 6 4 Putative ephrin-receptor like HYR PF02494.16 OWF49853.1 - 1e-25 89.8 1.6 3.6e-15 56.0 0.1 2.8 2 0 0 2 2 2 2 HYR domain TSP_1 PF00090.19 OWF49853.1 - 2.3e-12 46.9 9.2 2.3e-12 46.9 9.2 5.3 5 0 0 5 5 5 1 Thrombospondin type 1 domain Sushi PF00084.20 OWF49853.1 - 6.3e-11 42.7 22.5 1.7e-08 35.0 1.2 8.3 7 1 1 8 8 8 3 Sushi repeat (SCR repeat) Laminin_G_3 PF13385.6 OWF49853.1 - 6.5e-06 26.4 0.5 6.5e-06 26.4 0.5 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 OWF49853.1 - 0.00088 19.5 36.3 0.0023 18.2 7.6 5.3 4 0 0 4 4 4 2 EGF-like domain NCD3G PF07562.14 OWF49853.1 - 0.0049 16.8 2.0 0.0049 16.8 2.0 9.6 6 3 5 11 11 11 5 Nine Cysteines Domain of family 3 GPCR DUF5011 PF16403.5 OWF49853.1 - 0.028 14.5 2.1 2.7 8.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) DUF1269 PF06897.12 OWF49853.1 - 2.4 8.5 6.2 5.6 7.3 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) MCLC PF05934.11 OWF49854.1 - 1.7e-14 53.5 0.0 2.1e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) Seipin PF06775.14 OWF49855.1 - 0.0024 18.0 2.6 16 5.5 0.0 4.0 1 1 2 4 4 4 2 Putative adipose-regulatory protein (Seipin) Borealin PF10512.9 OWF49855.1 - 0.0044 17.0 5.7 13 5.8 0.0 5.4 3 2 2 6 6 6 1 Cell division cycle-associated protein 8 hGDE_N PF14699.6 OWF49855.1 - 0.0058 16.7 3.7 14 5.9 0.3 5.1 4 2 1 5 5 5 2 N-terminal domain from the human glycogen debranching enzyme OsmC PF02566.19 OWF49855.1 - 0.0063 17.0 0.0 1.8 9.1 0.0 3.8 2 1 2 4 4 4 1 OsmC-like protein zf-TFIIB PF13453.6 OWF49855.1 - 0.11 11.9 5.8 62 3.0 0.0 5.5 6 1 1 7 7 7 0 Transcription factor zinc-finger DUF3859 PF12975.7 OWF49855.1 - 0.15 12.1 0.8 4.7 7.2 0.1 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF3859) DUF2614 PF11023.8 OWF49855.1 - 0.28 11.3 15.9 5 7.3 0.1 5.4 2 1 1 5 5 5 0 Zinc-ribbon containing domain YbbR PF07949.12 OWF49855.1 - 2.2 8.7 6.3 17 5.9 0.0 4.5 2 2 2 4 4 4 0 YbbR-like protein LRR_8 PF13855.6 OWF49857.1 - 3.1e-47 158.2 77.8 5.2e-11 42.1 4.9 8.5 5 3 6 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 OWF49857.1 - 3.4e-44 148.1 55.6 2.6e-07 30.8 0.2 11.4 8 3 4 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF49857.1 - 1e-12 46.7 51.1 0.86 10.4 0.6 16.7 17 2 0 17 17 17 7 Leucine Rich Repeat LRR_9 PF14580.6 OWF49857.1 - 1.9e-09 37.3 25.9 0.0032 17.0 0.5 5.7 2 2 3 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 OWF49857.1 - 5.7e-05 22.8 52.0 4.9 7.5 0.1 14.5 15 0 0 15 15 15 5 Leucine Rich repeat Pkip-1 PF06878.11 OWF49857.1 - 0.17 12.0 0.6 0.48 10.5 0.1 2.1 2 0 0 2 2 2 0 Pkip-1 protein Glycos_transf_2 PF00535.26 OWF49858.1 - 1.1e-29 103.4 0.2 3.6e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF49858.1 - 2.1e-20 73.2 0.1 2.1e-20 73.2 0.1 2.1 2 0 0 2 2 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 OWF49858.1 - 8.4e-06 25.4 0.1 2.1e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase FAM60A PF15396.6 OWF49858.1 - 0.0016 18.5 3.7 0.0025 17.9 3.7 1.2 1 0 0 1 1 1 1 Protein Family FAM60A UPF0242 PF06785.11 OWF49858.1 - 0.0034 17.5 16.3 0.0055 16.8 16.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus O-antigen_lig PF13425.6 OWF49858.1 - 0.029 13.2 9.9 0.042 12.6 9.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Zip PF02535.22 OWF49858.1 - 0.062 12.5 1.1 0.087 12.0 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OWF49858.1 - 0.083 12.9 3.6 0.13 12.3 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF3_subunit PF08597.10 OWF49858.1 - 0.087 12.7 14.3 0.14 12.1 14.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DDHD PF02862.17 OWF49858.1 - 0.11 12.7 3.8 0.16 12.1 3.8 1.2 1 0 0 1 1 1 0 DDHD domain CTNNB1_binding PF08347.11 OWF49858.1 - 0.14 12.3 4.7 0.27 11.4 4.7 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Exonuc_VII_L PF02601.15 OWF49858.1 - 0.22 11.0 10.5 0.32 10.5 10.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 OWF49858.1 - 0.25 9.2 11.6 0.36 8.7 11.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 OWF49858.1 - 0.71 8.1 9.0 0.91 7.7 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 OWF49858.1 - 1.4 7.8 11.3 2.1 7.3 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RP-C_C PF11800.8 OWF49858.1 - 1.7 8.7 10.3 2.8 8.0 10.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.7 OWF49858.1 - 1.8 6.6 9.5 2.4 6.2 9.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLN3 PF02487.17 OWF49858.1 - 1.9 7.5 5.1 3 6.8 5.1 1.3 1 0 0 1 1 1 0 CLN3 protein Coilin_N PF15862.5 OWF49858.1 - 2.6 7.8 17.0 5.6 6.8 17.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus Phlebovirus_NSM PF07246.11 OWF49858.1 - 4.4 6.6 12.2 7.3 5.9 12.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M NARP1 PF12569.8 OWF49858.1 - 4.7 6.0 17.8 7.4 5.4 17.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 OWF49858.1 - 9.8 4.8 13.4 14 4.3 13.4 1.1 1 0 0 1 1 1 0 Presenilin MOZART1 PF12554.8 OWF49859.1 - 3.4e-05 23.5 20.0 25 4.7 0.0 10.6 1 1 14 15 15 15 4 Mitotic-spindle organizing gamma-tubulin ring associated DUF3902 PF13042.6 OWF49859.1 - 0.0014 18.2 15.7 0.51 9.9 0.5 3.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3902) SL4P PF17618.2 OWF49859.1 - 0.11 12.5 7.2 13 5.9 0.2 3.9 1 1 3 5 5 5 0 Uncharacterized Strongylid L4 protein LNS2 PF08235.13 OWF49859.1 - 0.66 9.4 8.1 21 4.5 0.2 3.7 1 1 3 5 5 5 0 LNS2 (Lipin/Ned1/Smp2) GBR2_CC PF18455.1 OWF49859.1 - 1.4 9.1 12.4 2e+02 2.2 0.1 6.6 8 1 1 9 9 9 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Peptidase_S10 PF00450.22 OWF49860.1 - 9.2e-102 341.6 1.4 1.2e-101 341.2 1.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CUB PF00431.20 OWF49861.1 - 8.8e-71 235.3 9.1 7.5e-13 48.8 0.3 9.4 9 0 0 9 9 9 9 CUB domain CUB PF00431.20 OWF49862.1 - 2.5e-23 82.5 3.9 2.5e-11 43.9 0.0 4.5 4 1 0 4 4 4 4 CUB domain zf-RING_UBOX PF13445.6 OWF49863.1 - 2.3e-08 33.9 7.4 2.3e-08 33.9 7.4 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF49863.1 - 2.8e-07 30.3 10.8 2.8e-07 30.3 10.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF49863.1 - 1.1e-06 28.3 6.5 1.1e-06 28.3 6.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF49863.1 - 1e-05 25.8 10.5 1e-05 25.8 10.5 2.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF49863.1 - 2.5e-05 24.1 9.3 2.5e-05 24.1 9.3 3.2 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF49863.1 - 4.2e-05 23.3 15.6 0.0016 18.3 10.4 3.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OWF49863.1 - 0.00028 20.7 13.0 0.00028 20.7 13.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF49863.1 - 0.0055 16.7 7.1 0.042 13.9 0.2 4.1 5 0 0 5 5 5 1 NHL repeat SBBP PF06739.11 OWF49863.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-propeller repeat zf-C3HC4_4 PF15227.6 OWF49863.1 - 1.1 9.4 18.1 0.075 13.2 11.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OWF49863.1 - 8.5 6.2 9.5 8.2 6.3 6.5 2.6 2 0 0 2 2 2 0 RING-like zinc finger HCV_NS5a_1b PF08301.13 OWF49864.1 - 0.00081 19.9 26.4 31 5.2 0.4 6.9 1 1 4 7 7 7 7 Hepatitis C virus non-structural 5a domain 1b Ank_5 PF13857.6 OWF49865.1 - 5.3e-26 90.3 1.0 3.5e-06 27.2 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF49865.1 - 1e-23 83.7 1.3 6e-08 33.2 0.4 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF49865.1 - 1.1e-22 80.0 3.2 3.1e-06 27.6 0.0 7.2 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF49865.1 - 2.6e-21 73.4 6.4 9e-05 22.6 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 OWF49865.1 - 4.7e-16 58.4 9.7 0.0001 22.6 0.0 7.5 7 1 0 7 7 7 4 Ankyrin repeat B_solenoid_ydck PF18836.1 OWF49866.1 - 0.29 11.1 4.6 57 3.8 0.0 5.2 8 0 0 8 8 8 0 Beta solenoid repeat from YDCK Peptidase_C13 PF01650.18 OWF49867.1 - 3.5e-46 157.8 0.0 4.8e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family CPSase_L_D3 PF02787.19 OWF49867.1 - 0.1 12.9 0.0 7 7.0 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ADK PF00406.22 OWF49868.1 - 1.2e-221 726.6 3.6 1e-51 175.0 0.0 5.1 5 0 0 5 5 5 5 Adenylate kinase AAA_17 PF13207.6 OWF49868.1 - 7e-153 502.5 7.0 2.5e-34 118.6 0.1 5.2 5 0 0 5 5 5 5 AAA domain AAA_18 PF13238.6 OWF49868.1 - 1.3e-39 135.8 0.4 1e-08 35.8 0.1 5.7 5 0 0 5 5 5 5 AAA domain AAA_33 PF13671.6 OWF49868.1 - 1e-35 123.0 0.0 5.9e-07 29.7 0.0 6.0 5 1 0 5 5 5 5 AAA domain Zeta_toxin PF06414.12 OWF49868.1 - 2.4e-13 49.8 3.0 0.053 12.8 0.0 5.8 6 0 0 6 6 5 4 Zeta toxin AAA_28 PF13521.6 OWF49868.1 - 1.1e-10 42.1 0.3 2.5 8.3 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.6 OWF49868.1 - 4.9e-10 39.9 17.2 0.5 10.7 0.0 6.8 7 0 0 7 7 7 4 AAA domain AAA PF00004.29 OWF49868.1 - 1.2e-09 38.7 4.8 0.36 11.3 0.1 6.5 5 3 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF49868.1 - 1.6e-09 38.2 5.5 3.1 8.1 0.1 5.9 5 1 0 5 5 5 3 AAA domain Cytidylate_kin PF02224.18 OWF49868.1 - 1.8e-09 37.6 0.8 0.29 10.8 0.0 4.8 4 1 0 4 4 4 2 Cytidylate kinase Ploopntkinase3 PF18751.1 OWF49868.1 - 1.9e-09 37.7 2.4 0.32 10.9 0.0 6.2 6 0 0 6 6 6 2 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 OWF49868.1 - 3.5e-07 30.8 6.8 0.22 12.0 0.0 5.8 5 0 0 5 5 5 1 ABC transporter CPT PF07931.12 OWF49868.1 - 8.8e-07 28.9 0.1 2 8.2 0.0 5.1 5 0 0 5 5 5 1 Chloramphenicol phosphotransferase-like protein Thymidylate_kin PF02223.17 OWF49868.1 - 3.1e-06 27.0 21.5 0.64 9.7 0.0 9.0 8 2 2 10 10 10 1 Thymidylate kinase AAA_30 PF13604.6 OWF49868.1 - 4.3e-05 23.3 8.5 6.3 6.5 0.0 5.4 5 0 0 5 5 5 0 AAA domain Hydin_ADK PF17213.3 OWF49868.1 - 7.5e-05 23.1 0.0 1.4 9.2 0.0 5.2 5 0 0 5 5 5 1 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 OWF49868.1 - 0.0002 21.8 3.7 12 6.2 0.0 5.6 6 0 0 6 6 5 0 AAA ATPase domain T2SSE PF00437.20 OWF49868.1 - 0.0013 17.8 3.8 16 4.5 0.0 4.9 5 0 0 5 5 5 0 Type II/IV secretion system protein NB-ARC PF00931.22 OWF49868.1 - 0.0015 17.8 7.5 7.2 5.7 0.1 4.9 5 0 0 5 5 5 0 NB-ARC domain DUF5599 PF18141.1 OWF49868.1 - 0.0032 17.7 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5599) AAA_24 PF13479.6 OWF49868.1 - 0.0041 16.9 5.8 26 4.5 0.1 5.5 5 0 0 5 5 5 0 AAA domain Sigma54_activ_2 PF14532.6 OWF49868.1 - 0.0044 17.1 1.9 22 5.2 0.0 4.9 5 0 0 5 5 5 0 Sigma-54 interaction domain NTPase_1 PF03266.15 OWF49868.1 - 0.0083 16.0 12.7 5.4 6.9 0.0 5.2 5 0 0 5 5 5 0 NTPase DUF5586 PF17824.1 OWF49868.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5586) RuvB_N PF05496.12 OWF49868.1 - 0.018 14.8 1.5 23 4.7 0.0 4.7 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OWF49868.1 - 0.03 13.7 9.3 4.8 6.5 0.0 5.4 5 0 0 5 5 5 0 KaiC GATase PF00117.28 OWF49868.1 - 0.046 13.5 2.6 18 5.0 0.0 4.6 5 0 0 5 5 5 0 Glutamine amidotransferase class-I Rad17 PF03215.15 OWF49868.1 - 0.076 12.9 2.2 14 5.5 0.0 4.2 5 0 0 5 5 5 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 OWF49868.1 - 0.1 11.9 2.4 61 2.8 0.0 4.8 5 0 0 5 5 5 0 FtsK/SpoIIIE family Sof1 PF04158.14 OWF49868.1 - 0.12 12.7 0.2 9.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Sof1-like domain RNA_pol_Rpb2_2 PF04561.14 OWF49868.1 - 0.17 11.5 0.4 68 3.0 0.0 3.8 4 0 0 4 4 4 0 RNA polymerase Rpb2, domain 2 SRP54 PF00448.22 OWF49868.1 - 0.22 11.1 9.0 2.6 7.6 0.1 5.2 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 OWF49868.1 - 0.3 10.3 9.6 15 4.6 0.1 4.7 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2075) CobU PF02283.16 OWF49868.1 - 0.41 10.2 3.3 1e+02 2.4 0.0 5.1 5 0 0 5 5 5 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NACHT PF05729.12 OWF49868.1 - 0.88 9.5 12.9 31 4.5 0.0 5.6 5 1 1 6 6 6 0 NACHT domain Cylicin_N PF15241.6 OWF49868.1 - 0.9 9.7 3.5 1.9 8.6 3.5 1.5 1 0 0 1 1 1 0 Cylicin N-terminus KTI12 PF08433.10 OWF49868.1 - 3 7.2 10.4 17 4.8 0.1 4.6 5 0 0 5 5 5 0 Chromatin associated protein KTI12 MeaB PF03308.16 OWF49868.1 - 3.8 6.4 9.8 29 3.5 0.1 4.4 5 0 0 5 5 5 0 Methylmalonyl Co-A mutase-associated GTPase MeaB tRNA_lig_kinase PF08303.11 OWF49868.1 - 5.2 7.1 6.9 67 3.5 0.1 4.6 5 1 0 5 5 3 0 tRNA ligase kinase domain ATP_bind_1 PF03029.17 OWF49868.1 - 8.2 6.1 20.9 14 5.4 0.2 5.7 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein Actin PF00022.19 OWF49870.1 - 4.8e-18 64.9 0.1 8.7e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Actin DUF3040 PF11239.8 OWF49870.1 - 0.0019 18.4 0.6 0.0019 18.4 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) Noggin PF05806.12 OWF49870.1 - 0.45 10.4 3.9 0.82 9.5 3.9 1.4 1 0 0 1 1 1 0 Noggin DUF913 PF06025.12 OWF49871.1 - 0.17 10.8 0.5 41 3.0 0.0 3.2 1 1 3 4 4 4 0 Domain of Unknown Function (DUF913) DUF4405 PF14358.6 OWF49872.1 - 0.23 12.0 1.2 51 4.5 1.2 3.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) E1_DerP2_DerF2 PF02221.15 OWF49873.1 - 1.5e-09 38.4 0.3 2e-09 38.0 0.3 1.2 1 0 0 1 1 1 1 ML domain Drf_FH1 PF06346.12 OWF49878.1 - 1.1e-15 57.7 0.0 0.0047 16.7 0.0 4.8 1 1 2 4 4 4 4 Formin Homology Region 1 SeqA_N PF17206.3 OWF49878.1 - 0.00045 19.5 24.4 64 3.0 0.0 17.0 17 6 8 25 25 25 0 SeqA protein N-terminal domain TsaE PF02367.17 OWF49878.1 - 0.0019 18.2 28.5 37 4.3 0.1 14.2 2 2 8 13 13 13 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3992 PF13157.6 OWF49878.1 - 1.3 9.8 26.2 1.1e+02 3.6 0.0 12.1 1 1 11 14 14 14 0 Protein of unknown function (DUF3992) HAUS4 PF14735.6 OWF49879.1 - 2.1e-69 233.8 5.5 2.1e-69 233.8 5.5 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 CHASE7 PF17151.4 OWF49879.1 - 0.047 13.3 1.1 0.46 10.1 0.0 2.6 3 0 0 3 3 3 0 Periplasmic sensor domain DUF3631 PF12307.8 OWF49879.1 - 0.061 13.5 1.9 0.11 12.7 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) SesA PF17107.5 OWF49879.1 - 0.073 13.3 3.3 2.1 8.6 0.2 3.5 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases N-Term_TEN PF11474.8 OWF49880.1 - 0.036 13.7 0.2 0.047 13.3 0.2 1.1 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Bunya_NS-S_2 PF03231.13 OWF49881.1 - 0.015 14.1 0.6 0.017 14.0 0.6 1.1 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-S TMEM95 PF15203.6 OWF49881.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 TMEM95 family Helicase_C PF00271.31 OWF49883.1 - 1.9e-13 50.7 0.0 3.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OWF49883.1 - 0.033 14.9 2.2 0.074 13.8 2.2 1.6 1 0 0 1 1 1 0 RecQ zinc-binding DUF2465 PF10239.9 OWF49883.1 - 0.11 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) OST_P2 PF18235.1 OWF49884.1 - 0.19 11.7 14.1 8.6 6.3 0.2 5.3 3 1 4 7 7 7 0 Oligosaccharyltransferase Peripheral 2 domain SNARE_assoc PF09335.11 OWF49885.1 - 6.8e-16 58.9 5.5 1.5e-15 57.7 5.5 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF443 PF04276.12 OWF49885.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF443) ECF-ribofla_trS PF07155.12 OWF49885.1 - 0.98 9.4 9.8 1.3 9.0 5.5 2.3 2 0 0 2 2 2 0 ECF-type riboflavin transporter, S component DUF2070 PF09843.9 OWF49885.1 - 5.5 5.2 11.9 4.3 5.5 5.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) TMEM70 PF06979.12 OWF49886.1 - 2.3e-41 141.3 3.8 4.4e-41 140.4 3.8 1.4 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DUF3087 PF11286.8 OWF49886.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Fanconi_A_N PF15865.5 OWF49887.1 - 3e-60 204.4 0.1 3e-60 204.4 0.1 3.0 2 1 1 3 3 3 1 Fanconi anaemia group A protein N terminus FERM_N PF09379.10 OWF49887.1 - 0.016 15.2 0.1 0.061 13.3 0.1 2.0 1 0 0 1 1 1 0 FERM N-terminal domain MA3 PF02847.17 OWF49887.1 - 0.044 13.8 0.6 2.2 8.3 0.0 3.8 4 0 0 4 4 4 0 MA3 domain Hyr1 PF15789.5 OWF49887.1 - 0.066 12.8 0.0 0.32 10.6 0.0 2.2 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 MIF4G PF02854.19 OWF49887.1 - 0.077 12.6 3.2 0.61 9.7 0.2 3.4 3 1 0 3 3 3 0 MIF4G domain Complex1_LYR PF05347.15 OWF49888.1 - 6.3e-06 26.2 0.1 1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OWF49888.1 - 0.015 16.0 0.0 0.021 15.6 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Nefa_Nip30_N PF10187.9 OWF49889.1 - 3.9e-25 88.2 13.5 6.1e-25 87.6 13.5 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4717 PF15838.5 OWF49889.1 - 0.14 12.2 2.7 0.31 11.1 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) Mss4 PF04421.13 OWF49890.1 - 1.3e-33 114.9 0.0 1.8e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein NOB1_Zn_bind PF08772.11 OWF49890.1 - 0.018 15.2 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DNA_ligase_OB_2 PF14743.6 OWF49891.1 - 2.6e-27 94.6 0.3 6.2e-27 93.4 0.3 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain zf-CCHH PF10283.9 OWF49891.1 - 1.9e-17 62.9 17.4 8.4e-09 35.3 6.5 2.6 2 0 0 2 2 2 2 PBZ domain DNA_ligase_A_M PF01068.21 OWF49891.1 - 3.3e-13 49.8 0.1 7.1e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 OWF49891.1 - 2.5e-05 24.7 0.4 0.00019 21.8 0.4 2.1 1 1 0 1 1 1 1 RNA ligase Brr6_like_C_C PF10104.9 OWF49891.1 - 0.12 12.1 3.2 5 6.9 0.4 2.4 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain zf-CCCH_2 PF14608.6 OWF49891.1 - 6.7 7.3 9.9 25 5.5 3.8 3.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger AA_permease_2 PF13520.6 OWF49892.1 - 1.8e-60 205.0 35.8 2.2e-60 204.7 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF49892.1 - 3.7e-30 105.0 32.1 4.8e-30 104.6 31.9 1.3 1 1 0 1 1 1 1 Amino acid permease Ndr PF03096.14 OWF49892.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Destabilase PF05497.12 OWF49893.1 - 1.9e-24 86.3 14.9 1.9e-24 86.3 14.9 1.6 2 0 0 2 2 2 1 Destabilase SH3_3 PF08239.11 OWF49893.1 - 0.004 17.4 0.4 0.01 16.1 0.4 1.7 1 1 0 1 1 1 1 Bacterial SH3 domain AMP-binding PF00501.28 OWF49894.1 - 2.2e-91 306.6 0.1 2.8e-91 306.2 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF49894.1 - 5.2e-16 59.4 0.1 2.9e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AA_permease_2 PF13520.6 OWF49895.1 - 1.1e-44 153.0 26.7 1.5e-44 152.5 26.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF49895.1 - 1.6e-22 79.8 22.3 3e-22 78.9 22.3 1.3 1 0 0 1 1 1 1 Amino acid permease ANAPC4_WD40 PF12894.7 OWF49896.1 - 3.8e-17 62.4 2.3 0.0011 19.2 0.0 7.2 3 3 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF49896.1 - 3.4e-15 56.2 12.5 0.0041 17.9 0.0 8.8 10 0 0 10 10 10 4 WD domain, G-beta repeat IKI3 PF04762.12 OWF49896.1 - 0.00015 19.9 0.6 0.93 7.4 0.0 3.3 3 1 0 3 3 3 3 IKI3 family Glyco_transf_11 PF01531.16 OWF49897.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 FAM167 PF11652.8 OWF49898.1 - 3e-06 27.6 14.2 0.19 12.2 0.7 3.7 1 1 3 4 4 4 3 FAM167 Stealth_CR2 PF11380.8 OWF49898.1 - 0.013 15.6 10.7 0.44 10.7 0.5 3.2 1 1 2 3 3 3 0 Stealth protein CR2, conserved region 2 LIN52 PF10044.9 OWF49898.1 - 0.028 15.1 13.8 3.6 8.4 0.7 4.6 1 1 3 4 4 4 0 Retinal tissue protein Vip3A_N PF12495.8 OWF49898.1 - 0.041 13.8 12.1 0.81 9.6 1.8 3.1 1 1 2 3 3 3 0 Vegetative insecticide protein 3A N terminal RasGEF_N_2 PF14663.6 OWF49898.1 - 0.051 14.0 12.3 0.35 11.3 2.3 2.8 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2171 PF09939.9 OWF49898.1 - 0.062 13.6 18.7 25 5.3 0.1 6.7 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2171) DUF948 PF06103.11 OWF49898.1 - 0.15 12.3 17.5 3.9 7.8 2.7 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Carm_PH PF17888.1 OWF49898.1 - 0.19 12.1 17.2 11 6.4 2.2 5.2 1 1 5 6 6 6 0 Carmil pleckstrin homology domain ACT_4 PF13291.6 OWF49898.1 - 5.2 7.7 19.7 1.5 9.4 3.3 3.8 1 1 2 4 4 4 0 ACT domain IF-2 PF11987.8 OWF49899.1 - 0.022 14.9 0.3 0.026 14.6 0.3 1.1 1 0 0 1 1 1 0 Translation-initiation factor 2 Carm_PH PF17888.1 OWF49899.1 - 0.048 14.0 1.6 2 8.8 0.2 2.0 1 1 1 2 2 2 0 Carmil pleckstrin homology domain Cag12 PF13117.6 OWF49900.1 - 1.5e-05 25.4 21.8 0.71 10.4 0.5 4.7 1 1 5 6 6 6 6 Cag pathogenicity island protein Cag12 NEAT PF05031.12 OWF49900.1 - 0.026 15.1 10.5 14 6.4 1.1 3.9 1 1 1 2 2 2 0 Iron Transport-associated domain GerPE PF10970.8 OWF49900.1 - 0.11 12.7 3.8 39 4.4 0.1 3.0 1 1 2 3 3 3 0 Spore germination protein GerPE FANCI_HD1 PF14679.6 OWF49900.1 - 0.12 12.3 10.8 49 4.0 0.1 4.6 1 1 5 6 6 6 0 FANCI helical domain 1 IZUMO PF15005.6 OWF49900.1 - 0.25 11.8 2.8 17 5.9 0.2 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Chorein_N PF12624.7 OWF49900.1 - 0.73 10.0 12.2 46 4.2 0.2 4.0 1 1 3 4 4 4 0 N-terminal region of Chorein or VPS13 Antigen_C PF16364.5 OWF49900.1 - 0.99 9.8 13.6 4.4 7.7 2.5 2.9 1 1 2 3 3 3 0 Cell surface antigen C-terminus RhoGEF PF00621.20 OWF49901.1 - 2.6e-15 57.1 2.1 3.4e-15 56.8 1.0 1.8 2 0 0 2 2 2 1 RhoGEF domain C2 PF00168.30 OWF49901.1 - 2.9e-15 56.4 0.0 5.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 OWF49901.1 - 1.9e-12 46.8 0.7 5.1e-12 45.5 0.7 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF49901.1 - 2.3e-07 31.1 0.1 5.2e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF49901.1 - 1.4e-06 28.5 0.1 5.3e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 OWF49901.1 - 0.0071 16.3 0.1 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain PH PF00169.29 OWF49901.1 - 0.057 13.9 0.1 0.2 12.2 0.1 1.9 1 0 0 1 1 1 0 PH domain Ecl1 PF12855.7 OWF49901.1 - 0.38 11.9 12.5 0.19 12.9 9.5 2.0 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Miga PF10265.9 OWF49902.1 - 2.3e-143 479.0 0.5 3.2e-143 478.6 0.5 1.1 1 0 0 1 1 1 1 Mitoguardin MOLO1 PF17175.4 OWF49902.1 - 0.026 14.7 0.1 0.052 13.7 0.1 1.5 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 TMEM154 PF15102.6 OWF49902.1 - 0.027 14.4 0.3 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family SSF PF00474.17 OWF49903.1 - 3.6e-125 418.0 22.5 5.8e-125 417.3 22.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4231 PF14015.6 OWF49903.1 - 6 7.4 12.3 4 8.0 0.2 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) SSF PF00474.17 OWF49904.1 - 4.4e-81 272.8 14.6 4.4e-81 272.8 14.6 2.0 1 1 2 3 3 3 1 Sodium:solute symporter family Tyrosinase PF00264.20 OWF49905.1 - 1.6e-33 116.9 7.9 1.5e-16 61.4 0.0 3.1 2 1 1 3 3 3 2 Common central domain of tyrosinase YdjO PF14169.6 OWF49905.1 - 0.048 13.4 0.6 0.15 11.8 0.3 2.0 2 0 0 2 2 2 0 Cold-inducible protein YdjO Lectin_C PF00059.21 OWF49906.1 - 2.7e-213 694.0 95.0 3.6e-21 75.9 0.3 12.2 12 0 0 12 12 12 12 Lectin C-type domain UL45 PF05473.12 OWF49906.1 - 1.2e-14 54.5 28.2 0.016 14.8 0.0 11.4 8 3 5 13 13 13 6 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF49906.1 - 1.9e-05 24.0 13.8 5.2 6.3 0.0 7.2 7 0 0 7 7 7 3 Chordopoxvirus A33R protein Podoplanin PF05808.11 OWF49906.1 - 0.0013 18.9 0.0 0.0039 17.3 0.0 1.8 2 0 0 2 2 2 1 Podoplanin Esterase_phd PF10503.9 OWF49907.1 - 2.1e-08 33.9 1.9 0.0018 17.8 0.1 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Xan_ur_permease PF00860.20 OWF49908.1 - 3.9e-85 285.9 26.3 3.9e-85 285.9 26.3 1.4 2 0 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 OWF49908.1 - 2.1 8.8 24.9 0.2 12.1 7.8 4.1 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily 7TMR-HDED PF07697.11 OWF49910.1 - 0.065 13.3 1.0 0.11 12.7 0.2 1.8 2 1 0 2 2 2 0 7TM-HD extracellular Nucleolin_bd PF16725.5 OWF49910.1 - 0.14 11.8 4.7 0.56 9.9 3.0 2.6 3 0 0 3 3 3 0 Nucleolin binding domain CAP PF00188.26 OWF49911.1 - 6.9e-10 39.8 0.8 1.3e-09 39.0 0.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ShK PF01549.24 OWF49911.1 - 0.85 10.2 9.1 0.6 10.7 6.8 2.1 2 0 0 2 2 2 0 ShK domain-like Aminotran_5 PF00266.19 OWF49913.1 - 6.8e-52 176.7 0.0 6.2e-26 91.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OWF49913.1 - 0.00057 19.3 4.9 0.012 15.0 1.8 2.8 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OWF49913.1 - 0.0024 17.1 1.5 1.4 8.0 0.1 2.7 3 0 0 3 3 3 2 Aminotransferase class I and II SepSecS PF05889.13 OWF49913.1 - 0.028 13.1 0.2 2.6 6.6 0.0 2.3 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 OWF49913.1 - 0.12 10.9 3.0 0.94 7.9 0.4 2.2 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Skp1 PF01466.19 OWF49913.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Drf_FH1 PF06346.12 OWF49915.1 - 6.2 6.5 65.4 17 5.1 29.1 3.5 1 1 2 3 3 3 0 Formin Homology Region 1 SF3b10 PF07189.11 OWF49916.1 - 3e-06 27.3 7.6 4.6 7.4 0.1 6.0 1 1 5 6 6 6 3 Splicing factor 3B subunit 10 (SF3b10) UBX PF00789.20 OWF49916.1 - 0.00045 20.4 7.2 0.35 11.1 0.3 3.3 1 1 2 3 3 3 3 UBX domain Cullin_binding PF03556.15 OWF49916.1 - 0.00077 19.9 5.1 2.9 8.3 5.2 3.2 1 1 0 1 1 1 1 Cullin binding ssDNA-exonuc_C PF10141.9 OWF49916.1 - 0.0091 15.7 2.3 3.3 7.3 0.0 3.6 1 1 4 5 5 5 1 Single-strand DNA-specific exonuclease, C terminal domain AvrPto PF11592.8 OWF49916.1 - 0.17 11.9 10.2 0.56 10.3 0.2 3.2 1 1 1 3 3 3 0 Central core of the bacterial effector protein AvrPto Catalase-rel PF06628.12 OWF49916.1 - 0.18 12.0 3.3 80 3.6 0.1 4.3 5 0 0 5 5 5 0 Catalase-related immune-responsive VirB8 PF04335.13 OWF49916.1 - 3.7 7.3 12.8 10 5.9 1.9 3.0 1 1 2 3 3 3 0 VirB8 protein EF-hand_1 PF00036.32 OWF49917.1 - 1.2e-14 52.6 5.6 0.00011 21.5 0.1 4.2 3 1 1 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF49917.1 - 1.3e-12 46.6 3.2 0.0014 18.0 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF49917.1 - 2e-11 42.9 1.8 0.029 14.3 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OWF49917.1 - 2.1e-09 37.7 5.2 0.0019 18.6 0.3 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 OWF49917.1 - 4.6e-06 26.4 3.3 0.28 11.0 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF49917.1 - 0.047 14.0 0.1 14 6.1 0.0 3.0 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.6 OWF49917.1 - 0.13 12.9 2.2 0.91 10.2 2.2 2.3 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.18 OWF49917.1 - 1 9.6 4.2 4.5 7.5 0.0 3.3 3 1 1 4 4 4 0 Dockerin type I domain EF-hand_1 PF00036.32 OWF49918.1 - 3.7e-10 38.6 7.9 0.044 13.4 0.1 4.2 3 1 1 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF49918.1 - 4.5e-10 38.6 4.4 0.0047 16.4 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF49918.1 - 2.1e-09 36.6 7.7 0.11 12.5 0.2 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OWF49918.1 - 1.3e-07 31.9 10.1 0.027 14.9 6.5 4.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF49918.1 - 0.0003 21.1 0.6 1.7 9.0 0.1 3.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 OWF49918.1 - 0.011 15.5 9.2 0.79 9.6 0.3 4.0 3 1 1 4 4 4 0 EF-hand domain pair VCBS PF13517.6 OWF49918.1 - 5.9 7.6 7.6 0.97 10.1 1.1 2.4 1 1 3 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF1416 PF07210.12 OWF49919.1 - 0.51 10.3 4.7 29 4.7 0.0 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF1416) FMO-like PF00743.19 OWF49920.1 - 2.1e-195 650.2 0.0 2.5e-195 649.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF49920.1 - 1.4e-20 73.8 0.1 5.6e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF49920.1 - 1.2e-13 51.0 0.7 7.8e-11 41.7 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OWF49920.1 - 1.9e-12 47.0 0.0 1.1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF49920.1 - 0.0006 20.3 0.0 0.058 14.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF49920.1 - 0.00093 19.4 0.0 0.0059 16.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF49920.1 - 0.003 16.8 0.1 1.8 7.7 0.1 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 OWF49920.1 - 0.011 14.5 0.7 1.3 7.7 0.6 2.3 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 OWF49920.1 - 0.11 11.7 0.1 5.8 6.2 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OWF49920.1 - 0.18 10.9 0.4 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 OWF49920.1 - 0.25 10.9 1.6 8.5 5.9 0.2 3.3 3 1 0 3 3 3 0 FAD dependent oxidoreductase FMO-like PF00743.19 OWF49921.1 - 6.4e-143 477.0 0.0 7.2e-143 476.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF49921.1 - 2.6e-14 53.2 0.4 9.9e-10 38.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF49921.1 - 1.1e-08 34.7 0.0 7.1e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF49921.1 - 6.9e-08 32.0 0.2 7e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 OWF49921.1 - 0.11 12.1 0.1 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 OWF49921.1 - 0.16 11.4 0.0 0.63 9.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OWF49921.1 - 0.17 12.5 0.2 0.45 11.1 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OWF49922.1 - 4.9e-45 154.0 0.0 5.5e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OWF49922.1 - 2.1e-05 24.7 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OWF49922.1 - 0.085 11.5 0.3 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OWF49922.1 - 0.096 11.9 0.4 0.14 11.4 0.3 1.3 1 1 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 OWF49922.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 OWF49923.1 - 1e-214 713.9 0.1 1.2e-214 713.6 0.1 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF49923.1 - 3.2e-21 75.9 1.6 7.7e-16 58.2 0.6 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF49923.1 - 3.2e-14 52.8 0.0 3.8e-13 49.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF49923.1 - 1.4e-11 44.1 0.3 9.9e-09 34.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OWF49923.1 - 9.7e-05 22.4 0.0 0.47 10.4 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF49923.1 - 0.00023 21.3 0.0 0.00056 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OWF49923.1 - 0.0023 18.4 0.4 0.16 12.5 0.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF49923.1 - 0.003 17.2 1.7 0.44 10.1 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF49923.1 - 0.013 14.8 0.2 0.83 8.8 0.1 2.4 2 0 0 2 2 2 0 Thi4 family IlvN PF07991.12 OWF49923.1 - 0.047 13.3 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 OWF49923.1 - 0.19 11.0 0.2 5.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OWF49923.1 - 0.31 9.7 1.2 2 7.0 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein zf-MYND PF01753.18 OWF49924.1 - 2.3e-10 40.4 12.4 2.3e-10 40.4 12.4 4.2 2 1 0 2 2 2 1 MYND finger SET PF00856.28 OWF49924.1 - 2.8e-05 24.6 0.1 0.00026 21.4 0.0 2.4 1 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 OWF49924.1 - 0.0018 18.5 0.0 0.0082 16.4 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Bcr-Abl_Oligo PF09036.10 OWF49924.1 - 0.27 11.3 1.8 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PhyH PF05721.13 OWF49925.1 - 5.6e-32 111.7 0.0 9.6e-32 111.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 OWF49925.1 - 0.0048 17.8 0.0 0.0094 16.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 OWF49925.1 - 0.038 14.4 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PhyH PF05721.13 OWF49926.1 - 2.4e-33 116.2 0.0 3.3e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OWF49926.1 - 9e-05 22.8 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OWF49926.1 - 0.0031 18.4 0.0 0.0059 17.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PapJ PF14855.6 OWF49927.1 - 0.084 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone BssS PF13991.6 OWF49929.1 - 0.04 14.0 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 BssS protein family ArAE_2_N PF10337.9 OWF49929.1 - 0.042 12.9 0.0 0.05 12.6 0.0 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF2279 PF10043.9 OWF49930.1 - 0.15 12.9 25.5 71 4.3 0.3 9.5 3 3 4 10 10 10 0 Predicted periplasmic lipoprotein (DUF2279) DUF2279 PF10043.9 OWF49931.1 - 0.3 11.9 3.2 33 5.3 0.1 3.3 2 2 1 3 3 3 0 Predicted periplasmic lipoprotein (DUF2279) IspD PF01128.19 OWF49934.1 - 4.7e-37 127.9 0.0 7.7e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 OWF49934.1 - 1.5e-08 35.2 0.0 3.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 OWF49934.1 - 0.0036 16.9 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NUC205 PF08168.11 OWF49934.1 - 0.09 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 NUC205 domain zf-C3HC4_3 PF13920.6 OWF49935.1 - 1.8e-07 30.9 7.1 3.4e-07 30.0 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 OWF49935.1 - 3.4e-07 30.0 4.6 3.4e-07 30.0 4.6 3.3 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 OWF49935.1 - 5.1e-07 29.4 10.8 1.2e-06 28.3 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF49935.1 - 2.3e-05 24.5 9.1 6.6e-05 23.0 9.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF49935.1 - 2.4e-05 24.1 11.6 5.2e-05 23.0 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF49935.1 - 2.5e-05 24.1 12.0 5.5e-05 23.1 12.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF49935.1 - 0.0001 22.2 10.6 0.00026 21.0 10.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF49935.1 - 0.00044 20.5 9.3 0.00044 20.5 9.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 OWF49935.1 - 0.00076 19.6 4.4 0.00076 19.6 4.4 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf_CCCH_4 PF18345.1 OWF49935.1 - 0.0021 18.1 6.8 0.0021 18.1 6.8 3.1 4 0 0 4 4 3 1 Zinc finger domain Prok-RING_4 PF14447.6 OWF49935.1 - 0.0022 17.8 6.3 0.0044 16.9 6.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OWF49935.1 - 0.024 14.5 5.7 0.055 13.3 5.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_4 PF18044.1 OWF49935.1 - 0.029 14.2 4.6 0.029 14.2 4.6 3.2 3 0 0 3 3 3 0 CCCH-type zinc finger zf-P11 PF03854.14 OWF49935.1 - 1.1 9.0 5.0 2.4 7.9 5.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger C1q PF00386.21 OWF49936.1 - 9.4e-24 84.0 2.6 1.1e-23 83.8 0.2 1.9 2 0 0 2 2 2 1 C1q domain HMMR_N PF15905.5 OWF49936.1 - 0.0092 15.5 0.4 0.012 15.1 0.4 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Nsp1_C PF05064.13 OWF49936.1 - 0.026 14.3 0.5 0.039 13.7 0.5 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region ADIP PF11559.8 OWF49936.1 - 0.026 14.6 2.3 0.037 14.1 2.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding C6 PF01681.17 OWF49936.1 - 0.043 14.3 0.1 0.24 12.0 0.0 2.1 2 1 0 2 2 2 0 C6 domain MIP-T3_C PF17749.1 OWF49936.1 - 0.044 13.8 1.4 0.063 13.2 1.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region HrpB7 PF09486.10 OWF49936.1 - 0.068 13.6 0.6 0.093 13.1 0.6 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ZapB PF06005.12 OWF49936.1 - 0.08 13.4 0.8 0.08 13.4 0.8 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DUF905 PF06006.12 OWF49936.1 - 0.082 12.9 0.1 0.25 11.3 0.1 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF905) BST2 PF16716.5 OWF49936.1 - 0.098 13.3 2.8 0.16 12.6 2.8 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 SlyX PF04102.12 OWF49936.1 - 0.29 11.8 4.1 0.5 11.0 4.1 1.3 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 OWF49936.1 - 0.48 10.2 4.5 1.4 8.7 3.5 1.9 1 1 1 2 2 2 0 Septum formation initiator MFS_1_like PF12832.7 OWF49937.1 - 7.6e-94 314.7 0.4 9.5e-94 314.4 0.4 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OWF49937.1 - 1.5e-26 93.2 22.2 1.4e-17 63.7 12.0 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OWF49937.1 - 3e-10 39.6 18.9 4.7e-07 29.1 6.8 3.2 3 0 0 3 3 3 3 Nucleoside H+ symporter MFS_2 PF13347.6 OWF49937.1 - 1.7e-05 23.6 17.4 0.0066 15.1 1.8 3.5 4 0 0 4 4 4 3 MFS/sugar transport protein LacY_symp PF01306.19 OWF49937.1 - 0.00019 20.3 23.4 0.0014 17.5 7.0 3.3 3 0 0 3 3 3 2 LacY proton/sugar symporter MFS_3 PF05977.13 OWF49937.1 - 0.069 11.5 3.1 0.14 10.5 1.8 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector NTP_transf_2 PF01909.23 OWF49938.1 - 0.00039 20.7 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OWF49938.1 - 0.0011 19.1 0.0 0.0037 17.3 0.0 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_central PF04928.17 OWF49938.1 - 0.01 14.8 2.3 0.54 9.2 0.0 3.0 3 0 0 3 3 3 0 Poly(A) polymerase central domain PAP_assoc PF03828.19 OWF49938.1 - 0.012 15.8 0.5 0.039 14.1 0.2 2.1 2 0 0 2 2 2 0 Cid1 family poly A polymerase DUF4269 PF14091.6 OWF49938.1 - 0.034 14.4 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) EF-hand_1 PF00036.32 OWF49939.1 - 1.8e-15 55.2 1.6 5.7e-06 25.5 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF49939.1 - 8.4e-15 53.4 1.0 1.2e-05 24.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OWF49939.1 - 3.7e-14 52.9 0.9 6.6e-07 29.7 1.3 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF49939.1 - 3.3e-09 36.5 1.9 7.8e-05 22.4 0.3 3.3 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF49939.1 - 2.3e-08 33.2 4.2 0.0016 17.8 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 OWF49939.1 - 2.9e-07 30.7 0.0 3.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain LXG PF04740.12 OWF49939.1 - 0.0013 18.4 0.4 0.19 11.4 0.0 2.1 2 0 0 2 2 2 2 LXG domain of WXG superfamily EF-hand_14 PF17959.1 OWF49939.1 - 0.13 12.6 0.2 23 5.4 0.0 2.7 1 1 1 2 2 2 0 EF-hand domain RAP PF08373.10 OWF49941.1 - 6.9e-05 22.9 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 RAP domain FAST_2 PF08368.12 OWF49941.1 - 0.021 15.6 0.4 0.33 11.7 0.2 2.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 ATP-cone PF03477.16 OWF49942.1 - 0.0091 16.6 4.5 21 5.8 0.0 6.2 3 3 6 9 9 9 2 ATP cone domain CX9C PF16860.5 OWF49943.1 - 5.7e-06 26.2 11.1 4.9e-05 23.3 0.8 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 OWF49943.1 - 0.015 15.5 2.3 0.015 15.5 2.3 3.0 2 1 1 3 3 3 0 CHCH domain Cmc1 PF08583.10 OWF49943.1 - 0.029 14.4 1.4 0.029 14.4 1.4 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like TIR_2 PF13676.6 OWF49944.1 - 4.2e-12 46.7 0.0 7.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF49944.1 - 6.8e-09 35.8 0.1 1.2e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 TIR domain Death PF00531.22 OWF49944.1 - 1.5e-08 34.7 0.5 5.1e-08 33.0 0.1 2.1 2 0 0 2 2 2 1 Death domain Proton_antipo_N PF00662.20 OWF49945.1 - 0.016 15.3 8.2 2.6 8.2 0.2 4.4 1 1 4 5 5 5 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF3868 PF12984.7 OWF49945.1 - 2.3 8.1 11.9 0.63 9.9 1.1 2.9 1 1 2 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3868) UPF0262 PF06793.12 OWF49946.1 - 0.0081 16.3 2.7 6.9 6.8 0.0 4.7 1 1 3 6 6 6 1 Uncharacterised protein family (UPF0262) DUF3110 PF11360.8 OWF49946.1 - 0.036 14.3 31.8 3.8 7.8 0.2 9.0 2 1 9 11 11 11 0 Protein of unknown function (DUF3110) DUF4825 PF16107.5 OWF49946.1 - 0.19 11.9 37.0 13 6.0 1.4 8.0 1 1 5 6 6 6 0 Domain of unknown function (DUF4825) PAXX PF15384.6 OWF49946.1 - 0.3 10.8 15.5 33 4.1 0.1 6.3 1 1 4 7 7 7 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 CARM1 PF11531.8 OWF49946.1 - 0.67 10.2 22.7 1.8 8.8 0.5 5.2 1 1 4 6 6 6 0 Coactivator-associated arginine methyltransferase 1 N terminal Proton_antipo_N PF00662.20 OWF49947.1 - 0.0011 19.0 13.4 3.2 7.9 0.6 4.8 1 1 5 6 6 6 5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NUC205 PF08168.11 OWF49947.1 - 0.0045 16.5 9.9 26 4.4 0.0 5.9 4 2 2 6 6 6 0 NUC205 domain Apolipoprotein PF01442.18 OWF49947.1 - 0.02 14.8 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1451 PF07295.11 OWF49947.1 - 0.02 14.9 0.1 0.034 14.2 0.0 1.3 1 1 0 1 1 1 0 Zinc-ribbon containing domain DUF4677 PF15726.5 OWF49947.1 - 0.39 10.9 10.7 0.57 10.3 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4677) DUF5106 PF17127.4 OWF49947.1 - 0.48 10.7 2.0 1.2 9.4 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5106) DUF3868 PF12984.7 OWF49947.1 - 1.4 8.8 22.3 1.1 9.1 1.5 4.3 1 1 4 5 5 5 0 Domain of unknown function, B. Theta Gene description (DUF3868) ACOX PF01756.19 OWF49947.1 - 7.6 6.1 14.3 14 5.1 0.5 4.0 1 1 4 5 5 5 0 Acyl-CoA oxidase Antirestrict PF03230.13 OWF49948.1 - 0.011 15.7 5.7 0.076 13.1 0.6 3.0 1 1 2 3 3 3 0 Antirestriction protein PAXX PF15384.6 OWF49948.1 - 0.051 13.3 0.6 11 5.7 0.1 2.7 1 1 1 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 OSR1_C PF12202.8 OWF49948.1 - 0.078 13.2 5.4 59 4.0 0.1 5.4 4 2 3 7 7 7 0 Oxidative-stress-responsive kinase 1 C-terminal domain Big_9 PF17963.1 OWF49948.1 - 0.17 12.7 12.2 4.2e+02 1.8 12.2 3.3 1 1 0 1 1 1 0 Bacterial Ig domain CRC_subunit PF08624.10 OWF49948.1 - 2.5 8.6 7.5 23 5.4 0.2 3.2 1 1 2 3 3 3 0 Chromatin remodelling complex Rsc7/Swp82 subunit CHRD PF07452.12 OWF49948.1 - 2.7 9.0 7.6 71 4.4 7.6 2.4 1 1 0 1 1 1 0 CHRD domain Big_8 PF17961.1 OWF49948.1 - 5.1 7.3 11.4 7.1 6.8 2.5 2.7 1 1 0 2 2 2 0 Bacterial Ig domain Proton_antipo_N PF00662.20 OWF49949.1 - 0.00072 19.6 13.3 2.8 8.1 0.5 5.0 1 1 3 4 4 4 4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Apolipoprotein PF01442.18 OWF49949.1 - 0.0017 18.3 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain NUC205 PF08168.11 OWF49949.1 - 0.079 12.5 9.6 26 4.4 0.0 5.9 3 2 3 7 7 7 0 NUC205 domain DUF3868 PF12984.7 OWF49949.1 - 0.2 11.5 24.4 1.2 8.9 1.4 4.4 1 1 3 4 4 4 0 Domain of unknown function, B. Theta Gene description (DUF3868) WD40_alt PF14077.6 OWF49949.1 - 0.7 9.8 2.1 1.4e+02 2.4 0.1 3.5 1 1 1 3 3 3 0 Alternative WD40 repeat motif Proton_antipo_N PF00662.20 OWF49950.1 - 0.0042 17.1 4.7 0.22 11.6 0.2 3.4 1 1 2 3 3 3 2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF3868 PF12984.7 OWF49950.1 - 0.81 9.5 8.4 10 6.0 4.2 3.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3868) 7tm_1 PF00001.21 OWF49951.1 - 0.0019 17.6 0.3 0.0024 17.2 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SNF PF00209.18 OWF49952.1 - 5.2e-182 606.2 39.9 1e-181 605.2 39.9 1.4 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Epiglycanin_C PF14654.6 OWF49952.1 - 0.52 10.4 6.0 0.15 12.1 1.0 2.7 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region COX4 PF02936.14 OWF49952.1 - 1.1 9.2 2.6 6 6.9 0.0 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Glyco_hydro_18 PF00704.28 OWF49953.1 - 6.8e-89 298.7 0.0 8.8e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ldl_recept_a PF00057.18 OWF49953.1 - 4.8e-21 74.7 29.4 2.5e-11 43.6 13.6 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DNMT1-RFD PF12047.8 OWF49953.1 - 0.054 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain S1-like PF14444.6 OWF49954.1 - 4.1 7.4 21.7 1.1e+02 2.8 0.1 8.8 5 4 8 13 13 13 0 S1-like dUTPase PF00692.19 OWF49955.1 - 3.8e-47 159.2 0.0 4.5e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase CFEM PF05730.11 OWF49956.1 - 1.3 9.2 7.2 2.2 8.5 0.6 2.6 3 0 0 3 3 3 0 CFEM domain zf-RING_2 PF13639.6 OWF49957.1 - 1.4e-14 54.1 7.9 3.8e-14 52.7 7.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF49957.1 - 1.4e-09 37.6 7.0 3.5e-09 36.4 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF49957.1 - 3.6e-09 36.2 4.7 3.6e-09 36.2 4.7 2.7 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OWF49957.1 - 2.8e-08 33.5 7.2 5.9e-08 32.5 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF49957.1 - 4.6e-08 32.8 4.7 1.1e-07 31.6 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF49957.1 - 6.7e-08 32.4 4.9 1.3e-07 31.5 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OWF49957.1 - 9e-07 29.1 13.0 9.3e-07 29.0 9.0 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF49957.1 - 1.3e-05 25.1 5.9 4.3e-05 23.5 5.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OWF49957.1 - 0.00011 21.9 4.3 0.00011 21.9 4.3 2.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 RINGv PF12906.7 OWF49957.1 - 0.0074 16.4 5.2 0.021 15.0 5.2 1.8 1 1 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 OWF49957.1 - 0.0077 16.3 4.0 0.0077 16.3 4.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OWF49957.1 - 0.0079 15.8 3.1 0.019 14.6 3.1 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OWF49957.1 - 0.19 11.5 4.5 0.5 10.2 4.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OWF49957.1 - 0.29 11.3 5.8 1.3 9.3 5.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 OWF49957.1 - 0.3 11.1 4.6 8.2 6.4 0.9 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 IBR PF01485.21 OWF49959.1 - 1.5e-07 31.5 38.5 7.2e-07 29.3 12.8 2.9 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain MCM PF00493.23 OWF49960.1 - 0.12 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain ubiquitin PF00240.23 OWF49961.1 - 6.8e-09 35.4 0.1 2.1e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OWF49961.1 - 0.0054 16.5 0.1 0.014 15.2 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 OWF49962.1 - 7.2e-05 22.9 44.2 0.0011 19.1 18.8 3.1 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain Epimerase PF01370.21 OWF49963.1 - 1.5e-26 93.4 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF49963.1 - 7.4e-17 61.7 0.0 9.3e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OWF49963.1 - 2.6e-10 39.8 0.0 7.9e-06 25.1 0.0 2.5 2 1 1 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OWF49963.1 - 3.2e-09 36.3 0.0 4.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OWF49963.1 - 1.3e-08 34.9 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OWF49963.1 - 0.00036 19.8 0.0 0.47 9.6 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 OWF49963.1 - 0.0098 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OWF49963.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 OWF49963.1 - 0.085 12.4 0.0 0.23 11.0 0.0 1.7 2 1 0 2 2 2 0 NmrA-like family Galactosyl_T PF01762.21 OWF49964.1 - 2.9e-39 134.9 0.3 3.9e-39 134.5 0.3 1.1 1 0 0 1 1 1 1 Galactosyltransferase MFS_1 PF07690.16 OWF49965.1 - 1.4e-08 34.0 44.3 1.7e-08 33.8 40.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily CCSMST1 PF15013.6 OWF49965.1 - 0.59 10.3 2.2 54 4.1 0.0 3.4 3 0 0 3 3 3 0 CCSMST1 family I-set PF07679.16 OWF49966.1 - 2.9e-46 155.4 0.0 2.6e-12 46.6 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF49966.1 - 1.7e-43 147.1 9.7 2.3e-11 44.1 0.3 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 OWF49966.1 - 7.4e-33 112.7 10.5 2.7e-07 30.8 0.0 5.2 4 1 1 5 5 5 4 Immunoglobulin domain ig PF00047.25 OWF49966.1 - 6.2e-20 71.2 14.7 1.3e-05 25.3 0.1 5.7 5 3 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 OWF49966.1 - 2.5e-13 50.1 12.6 0.0034 17.5 0.1 7.2 4 3 2 6 6 6 3 Immunoglobulin V-set domain LCCL PF03815.19 OWF49966.1 - 5.1e-12 45.7 1.4 1.4e-11 44.3 1.4 1.7 1 0 0 1 1 1 1 LCCL domain Collagen PF01391.18 OWF49966.1 - 1.5e-08 34.3 44.3 1.8e-08 34.0 22.5 3.1 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) C2-set_2 PF08205.12 OWF49966.1 - 3.7e-07 30.1 4.6 0.071 13.2 0.2 4.4 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 OWF49966.1 - 8.8e-05 22.0 0.1 0.31 10.6 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 OWF49966.1 - 0.032 14.5 0.0 55 4.1 0.0 3.7 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain B_lectin PF01453.24 OWF49966.1 - 0.076 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 D-mannose binding lectin LPMO_10 PF03067.15 OWF49967.1 - 2.9e-24 86.8 0.1 3.5e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading IgGFc_binding PF17517.2 OWF49968.1 - 8.5e-31 107.3 3.7 1.2e-30 106.8 3.7 1.2 1 0 0 1 1 1 1 IgGFc binding protein Cyclin_C_2 PF16899.5 OWF49969.1 - 3.3e-21 75.6 0.2 5.8e-20 71.6 0.0 2.5 2 1 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 OWF49969.1 - 2.6e-08 33.6 0.3 7e-08 32.3 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF49969.1 - 0.00038 20.5 0.3 0.0016 18.5 0.3 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.19 OWF49969.1 - 0.086 12.9 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat RUN PF02759.19 OWF49970.1 - 2.6e-09 37.2 0.0 5.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RUN domain CDO_I PF05995.12 OWF49971.1 - 2.6e-58 196.1 0.2 3.3e-58 195.7 0.2 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OWF49971.1 - 0.0015 18.0 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO AAA_6 PF12774.7 OWF49972.1 - 7.9e-165 547.6 0.1 1.2e-163 543.8 0.0 2.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF49972.1 - 2.2e-134 448.5 3.4 2.2e-134 448.5 3.4 3.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OWF49972.1 - 3.4e-110 367.5 0.2 2.2e-109 364.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OWF49972.1 - 7.4e-105 350.5 0.5 8.5e-103 343.8 0.0 3.9 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OWF49972.1 - 1e-96 322.3 0.3 6.9e-94 313.1 0.5 3.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF49972.1 - 3.6e-82 274.2 1.1 4e-75 251.3 0.0 4.9 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 OWF49972.1 - 4.4e-57 193.7 17.5 1.2e-56 192.3 17.5 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OWF49972.1 - 1.9e-55 187.1 0.1 8e-55 185.1 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OWF49972.1 - 9.9e-44 148.2 0.0 1.9e-42 144.1 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF49972.1 - 3.1e-23 82.3 4.7 7.9e-23 81.0 0.2 3.9 4 0 0 4 4 4 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF49972.1 - 1.2e-21 77.2 0.2 5.8e-07 29.6 0.0 6.0 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OWF49972.1 - 1.1e-19 70.5 0.1 7.1e-19 67.9 0.1 2.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OWF49972.1 - 1.1e-11 45.3 4.5 0.008 16.6 0.0 6.0 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OWF49972.1 - 1.8e-08 35.0 0.1 0.068 13.7 0.0 5.7 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 OWF49972.1 - 4.8e-08 33.4 3.5 0.33 11.2 0.0 5.7 5 1 0 5 5 4 2 AAA domain T2SSE PF00437.20 OWF49972.1 - 4.1e-07 29.3 0.1 0.014 14.5 0.0 3.7 4 0 0 4 4 4 2 Type II/IV secretion system protein RNA_helicase PF00910.22 OWF49972.1 - 5.9e-07 29.8 0.8 0.47 10.9 0.0 4.9 4 0 0 4 4 4 1 RNA helicase AAA_16 PF13191.6 OWF49972.1 - 0.00011 22.7 14.5 1.2 9.5 0.0 6.8 6 2 1 7 7 5 1 AAA ATPase domain Sigma54_activat PF00158.26 OWF49972.1 - 0.00011 22.0 0.9 0.14 11.8 0.0 4.0 4 0 0 4 4 4 1 Sigma-54 interaction domain TsaE PF02367.17 OWF49972.1 - 0.0006 19.8 3.4 9.1 6.3 0.0 4.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 OWF49972.1 - 0.021 13.8 2.4 1 8.2 0.0 4.4 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain TMF_TATA_bd PF12325.8 OWF49972.1 - 0.039 14.2 22.6 0.15 12.3 1.0 5.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Peptidase_S39 PF02122.15 OWF49972.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase S39 AAA_33 PF13671.6 OWF49972.1 - 0.069 13.3 1.2 1.6e+02 2.4 0.0 5.0 4 0 0 4 4 4 0 AAA domain DUF1640 PF07798.11 OWF49972.1 - 0.074 13.1 9.3 0.49 10.4 3.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) AAA_28 PF13521.6 OWF49972.1 - 0.085 13.1 1.3 1e+02 3.1 0.0 4.0 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 OWF49972.1 - 0.089 12.2 2.3 3.3 7.0 0.0 3.1 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OWF49972.1 - 0.093 12.6 0.6 8.9 6.2 0.0 4.0 4 0 0 4 4 4 0 NACHT domain AAA_29 PF13555.6 OWF49972.1 - 0.16 11.7 1.8 20 5.0 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Exonuc_VII_L PF02601.15 OWF49972.1 - 0.16 11.5 18.1 0.51 9.9 2.1 3.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit MoCF_biosynth PF00994.24 OWF49972.1 - 0.16 11.6 0.1 3.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Probable molybdopterin binding domain Pox_A32 PF04665.12 OWF49972.1 - 0.3 10.5 1.9 0.72 9.3 0.1 2.7 3 0 0 3 3 1 0 Poxvirus A32 protein GPS2_interact PF15784.5 OWF49972.1 - 0.32 11.5 6.9 2.8 8.4 0.2 3.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain ABC_tran PF00005.27 OWF49972.1 - 0.71 10.4 5.4 45 4.6 0.1 4.6 4 0 0 4 4 3 0 ABC transporter CEP63 PF17045.5 OWF49972.1 - 1.3 8.8 26.3 0.0087 16.0 4.3 3.8 3 0 0 3 3 3 0 Centrosomal protein of 63 kDa DUF853 PF05872.12 OWF49972.1 - 1.9 7.0 11.0 1.5 7.3 0.1 3.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF853) AAA_30 PF13604.6 OWF49972.1 - 3.2 7.4 9.0 7.2 6.3 0.1 4.5 5 0 0 5 5 4 0 AAA domain Tropomodulin PF03250.14 OWF49973.1 - 4e-50 169.5 5.4 4e-50 169.5 5.4 1.9 2 0 0 2 2 2 1 Tropomodulin LRR_4 PF12799.7 OWF49973.1 - 0.12 12.9 5.9 0.82 10.2 1.5 2.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) FumaraseC_C PF10415.9 OWF49973.1 - 0.14 12.6 2.5 0.26 11.7 0.0 2.6 3 0 0 3 3 3 0 Fumarase C C-terminus LRR_2 PF07723.13 OWF49973.1 - 0.17 12.6 1.1 4.8 8.0 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich Repeat TINF2_N PF14973.6 OWF49973.1 - 0.55 10.6 4.6 0.11 12.9 0.8 1.8 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Cactin_mid PF10312.9 OWF49973.1 - 3 7.5 11.3 1.6 8.4 6.3 2.7 2 1 0 2 2 2 0 Conserved mid region of cactin Ocnus PF05005.15 OWF49974.1 - 0.24 11.5 15.8 1.8e+04 -6.7 15.8 5.2 1 1 0 1 1 1 0 Janus/Ocnus family (Ocnus) NPFF PF15085.6 OWF49974.1 - 1.5 9.2 5.0 54 4.2 5.0 2.4 1 1 0 1 1 1 0 Neuropeptide FF N_NLPC_P60 PF12912.7 OWF49974.1 - 5.2 7.5 8.7 2.2e+03 -1.0 8.7 3.2 1 1 0 1 1 1 0 NLPC_P60 stabilising domain, N term TES PF08034.11 OWF49974.1 - 6.7 7.1 17.5 1.7e+04 -3.9 17.5 2.8 1 1 0 1 1 1 0 Trematode eggshell synthesis protein SGP PF17228.2 OWF49974.1 - 7.5 7.5 18.9 72 4.3 18.9 2.0 1 1 0 1 1 1 0 Sulphur globule protein DUF2911 PF11138.8 OWF49974.1 - 8.2 6.3 10.7 4.2 7.2 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2911) Galactosyl_T PF01762.21 OWF49976.1 - 5.6e-42 143.8 0.0 1.3e-41 142.6 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF49976.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 zf-H2C2_2 PF13465.6 OWF49977.1 - 6.3e-55 181.3 79.1 7.9e-07 29.2 2.4 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 OWF49977.1 - 4.6e-50 165.4 96.0 9.1e-06 25.9 0.9 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF49977.1 - 4e-44 145.4 89.4 8e-05 23.2 0.6 13.2 13 0 0 13 13 13 12 C2H2-type zinc finger zf-met PF12874.7 OWF49977.1 - 1e-27 95.7 73.9 0.0047 17.3 1.9 13.0 13 0 0 13 13 13 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF49977.1 - 1.6e-25 88.8 64.7 0.00044 20.5 2.7 12.5 12 0 0 12 12 12 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF49977.1 - 2.4e-21 75.3 90.7 0.0021 18.0 0.4 13.2 13 0 0 13 13 13 11 C2H2-type zinc finger BolA PF01722.18 OWF49977.1 - 2.5e-13 50.1 13.4 0.0021 18.3 0.1 8.1 3 3 5 9 9 9 3 BolA-like protein DUF678 PF05077.12 OWF49977.1 - 3.2e-05 24.0 3.5 3.2e-05 24.0 3.5 4.7 3 2 2 5 5 5 1 Protein of unknown function (DUF678) zf-C2H2_8 PF15909.5 OWF49977.1 - 0.0075 16.5 48.4 1.7 9.0 6.4 6.6 1 1 6 8 8 8 6 C2H2-type zinc ribbon Sprouty PF05210.13 OWF49977.1 - 0.015 15.7 1.9 0.015 15.7 1.9 5.2 3 3 2 5 5 3 0 Sprouty protein (Spry) zf-C2HC_2 PF13913.6 OWF49977.1 - 0.054 13.4 0.0 0.054 13.4 0.0 10.4 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf-trcl PF13451.6 OWF49977.1 - 0.14 12.1 0.3 0.14 12.1 0.3 10.2 12 1 0 12 12 12 0 Probable zinc-ribbon domain Zf_RING PF16744.5 OWF49977.1 - 0.26 11.4 63.8 4.6 7.4 0.2 11.4 2 2 9 12 12 12 0 KIAA1045 RING finger MPS2 PF17060.5 OWF49978.1 - 0.0018 17.6 1.9 0.003 16.9 1.9 1.4 1 0 0 1 1 1 1 Monopolar spindle protein 2 FliJ PF02050.16 OWF49978.1 - 0.061 13.5 13.8 0.4 10.9 0.4 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.9 OWF49978.1 - 0.14 12.2 10.2 0.3 11.1 4.8 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 OWF49978.1 - 0.62 10.6 3.5 5.3 7.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 OmpH PF03938.14 OWF49978.1 - 0.74 10.1 7.2 0.43 10.9 2.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TACC_C PF05010.14 OWF49978.1 - 2 8.2 16.9 0.35 10.6 9.1 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Phage_Mu_Gam PF07352.12 OWF49978.1 - 2.2 8.2 10.3 0.88 9.5 0.8 3.4 3 1 1 4 4 4 0 Bacteriophage Mu Gam like protein DUF4407 PF14362.6 OWF49978.1 - 2.4 7.4 5.9 0.97 8.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 OWF49978.1 - 4 8.0 9.5 29 5.2 0.2 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Fib_alpha PF08702.10 OWF49978.1 - 4.6 7.4 8.9 10 6.3 5.0 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DSPc PF00782.20 OWF49979.1 - 1e-31 109.5 0.0 1.5e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DnaJ PF00226.31 OWF49980.1 - 7.3e-17 61.2 0.1 1.4e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain FA_hydroxylase PF04116.13 OWF49980.1 - 0.0049 17.2 0.4 0.0092 16.3 0.4 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily LRAT PF04970.13 OWF49981.1 - 5.5e-29 101.0 0.0 6.8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF49981.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Calici_PP_N PF08405.11 OWF49981.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Viral polyprotein N-terminal YHYH PF14240.6 OWF49982.1 - 0.0014 18.7 12.5 31 4.4 0.0 6.6 1 1 6 7 7 7 3 YHYH protein Drf_FH1 PF06346.12 OWF49982.1 - 0.018 14.7 9.2 0.039 13.7 9.2 1.6 1 1 0 1 1 1 0 Formin Homology Region 1 amfpi-1 PF12190.8 OWF49982.1 - 0.22 12.2 8.5 15 6.3 1.6 2.8 1 1 0 2 2 2 0 Fungal protease inhibitor GPCR_chapero_1 PF11904.8 OWF49983.1 - 1.4e-65 221.8 0.2 2.1e-65 221.2 0.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 OWF49983.1 - 6.3e-10 39.5 0.1 1.1e-09 38.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF49983.1 - 1.1e-08 34.6 0.4 8.6e-05 22.7 0.4 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OWF49983.1 - 2e-08 34.6 0.0 5.8e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF49983.1 - 1.2e-07 31.9 1.9 6.6e-07 29.5 1.3 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OWF49983.1 - 4.6e-07 30.0 0.0 1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) fn3 PF00041.21 OWF49984.1 - 0.0003 21.1 15.0 0.026 14.9 0.5 5.2 5 0 0 5 5 5 2 Fibronectin type III domain Interfer-bind PF09294.10 OWF49984.1 - 0.0014 18.9 3.7 0.05 13.9 0.2 3.4 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF4773 PF15998.5 OWF49984.1 - 0.0082 16.7 0.3 0.086 13.4 0.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4773) CortBP2 PF09727.9 OWF49985.1 - 2.2e-05 24.5 0.0 0.64 9.9 0.0 4.2 2 2 2 4 4 4 2 Cortactin-binding protein-2 GcrA PF07750.11 OWF49985.1 - 0.00032 21.1 12.5 22 5.4 0.7 7.6 1 1 3 4 4 4 1 GcrA cell cycle regulator PBP5_C PF07943.13 OWF49985.1 - 0.0083 16.3 0.0 21 5.4 0.0 5.2 4 3 0 5 5 5 1 Penicillin-binding protein 5, C-terminal domain DUF3320 PF11784.8 OWF49985.1 - 0.084 12.8 2.6 50 4.0 0.0 6.7 5 2 4 9 9 9 0 Protein of unknown function (DUF3320) P22_portal PF16510.5 OWF49985.1 - 0.51 8.9 17.2 6.9 5.1 0.2 5.3 1 1 5 6 6 6 0 Phage P22-like portal protein TbpB_B_D PF01298.18 OWF49985.1 - 0.76 10.2 12.1 45 4.4 5.2 4.5 1 1 1 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Clathrin PF00637.20 OWF49987.1 - 1.6e-208 683.0 47.0 6.3e-35 120.1 1.6 8.1 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 OWF49987.1 - 2.2e-44 147.7 4.9 1.7e-08 34.4 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 OWF49987.1 - 9e-34 115.2 0.4 4.7e-33 112.9 0.4 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 OWF49987.1 - 1.5e-10 40.3 0.1 4.7e-10 38.6 0.1 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 OWF49987.1 - 1e-06 28.1 6.6 8.7e-05 21.7 0.1 4.0 4 0 0 4 4 4 2 Coatomer WD associated region TPR_2 PF07719.17 OWF49987.1 - 0.00054 19.9 4.0 4.6 7.6 0.0 5.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF49987.1 - 0.00076 19.3 8.3 0.51 10.5 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF49987.1 - 0.0055 17.4 5.8 20 6.4 0.0 6.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF49987.1 - 0.01 16.3 3.2 12 6.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OWF49987.1 - 0.4 11.0 4.7 15 6.1 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF49987.1 - 0.66 9.9 9.9 0.88 9.5 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF49987.1 - 0.77 10.0 4.9 9.1 6.6 0.0 4.9 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 adh_short PF00106.25 OWF49988.1 - 2.2e-46 157.8 1.1 2.6e-46 157.6 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF49988.1 - 5.5e-45 153.7 0.1 6.6e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF49988.1 - 1.4e-09 38.1 2.8 2.5e-09 37.3 2.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF49988.1 - 0.0059 16.1 0.3 0.012 15.1 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4514 PF14986.6 OWF49988.1 - 0.043 13.8 0.4 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) DFP PF04127.15 OWF49988.1 - 0.093 12.6 2.2 1.1 9.1 0.4 2.2 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein wnt PF00110.19 OWF49989.1 - 6.5e-128 426.6 25.3 7.5e-128 426.5 25.3 1.0 1 0 0 1 1 1 1 wnt family Linker_histone PF00538.19 OWF49989.1 - 0.037 14.4 0.0 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 linker histone H1 and H5 family DUF778 PF05608.12 OWF49990.1 - 2.8e-41 142.0 7.1 7e-24 85.2 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) FHA PF00498.26 OWF49991.1 - 2.8e-10 40.4 0.1 6.4e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 FHA domain PHD PF00628.29 OWF49991.1 - 0.00066 19.5 13.1 0.0015 18.3 13.1 1.6 1 0 0 1 1 1 1 PHD-finger DUF4718 PF15842.5 OWF49991.1 - 9.9 5.9 19.1 10 5.9 16.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) LRR_4 PF12799.7 OWF49993.1 - 3.6e-13 49.4 7.2 9.7e-06 25.8 1.5 4.1 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF49993.1 - 1.4e-10 41.0 0.4 4.1e-05 23.2 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OWF49993.1 - 2.1e-07 30.6 8.5 0.0047 16.7 0.2 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 OWF49993.1 - 0.0057 17.0 0.5 16 6.5 0.0 3.8 3 1 0 3 3 3 2 Leucine Rich Repeat Ribosomal_S10 PF00338.22 OWF49994.1 - 1.8e-25 89.0 0.8 3.9e-25 87.9 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e RRM_1 PF00076.22 OWF49994.1 - 4.6e-10 39.2 0.0 0.00061 19.6 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_lid_5 PF17865.1 OWF49994.1 - 0.036 14.1 0.4 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 Midasin AAA lid domain RRM_occluded PF16842.5 OWF49994.1 - 0.05 13.5 0.0 2.7 7.9 0.0 2.7 2 1 0 2 2 2 0 Occluded RNA-recognition motif RRM_1 PF00076.22 OWF49995.1 - 1.4e-17 63.2 0.0 1.9e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 OWF49995.1 - 1.4e-08 34.4 4.7 2.8e-08 33.4 4.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OWF49995.1 - 0.0012 18.8 1.2 0.0023 17.9 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OWF49995.1 - 0.03 14.1 4.5 0.076 12.9 4.5 1.7 1 0 0 1 1 1 0 Zinc knuckle RNA_bind PF08675.11 OWF49995.1 - 0.086 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain RRM_5 PF13893.6 OWF49995.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF49995.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OWF49995.1 - 0.21 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 zf-CCHC_5 PF14787.6 OWF49995.1 - 0.34 10.6 9.5 0.13 12.0 5.4 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CCDC85 PF10226.9 OWF49996.1 - 8.8e-65 218.0 4.4 8.8e-65 218.0 4.4 2.1 3 0 0 3 3 3 1 CCDC85 family TSC22 PF01166.18 OWF49996.1 - 0.16 12.3 3.4 3.8 7.9 0.6 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Syndecan PF01034.20 OWF49997.1 - 0.17 11.8 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain RepB PF07506.11 OWF49998.1 - 0.57 10.2 11.2 4 7.5 0.1 6.0 3 3 2 7 7 7 0 RepB plasmid partitioning protein DUF1187 PF06688.11 OWF49999.1 - 0.0013 19.0 2.3 22 5.5 0.1 4.2 1 1 3 4 4 4 2 Protein of unknown function (DUF1187) HCV_capsid PF01543.17 OWF49999.1 - 4.7 7.5 10.4 5.1 7.3 1.5 2.2 1 1 1 2 2 2 0 Hepatitis C virus capsid protein IDO PF01231.18 OWF50000.1 - 4.4e-76 256.4 0.0 1.6e-75 254.6 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase MitMem_reg PF13012.6 OWF50000.1 - 0.097 13.1 0.2 1.6 9.2 0.2 2.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Cnd1 PF12717.7 OWF50000.1 - 0.099 12.7 0.5 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Rad52_Rad22 PF04098.15 OWF50000.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Malectin PF11721.8 OWF50001.1 - 5.2e-45 153.5 0.1 6.4e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 Malectin domain Astacin PF01400.24 OWF50002.1 - 4.7e-49 166.6 0.5 9.1e-49 165.7 0.5 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 OWF50002.1 - 2.1e-27 96.0 1.0 4.6e-27 94.9 1.0 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu CUB PF00431.20 OWF50002.1 - 1e-07 32.3 0.0 2.1e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 CUB domain Peptidase_M10 PF00413.24 OWF50002.1 - 0.00018 21.4 1.2 0.14 12.0 0.3 2.4 1 1 0 2 2 2 2 Matrixin Reprolysin_3 PF13582.6 OWF50002.1 - 0.00038 21.0 0.1 0.0011 19.5 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Exo_endo_phos PF03372.23 OWF50004.1 - 2.4e-10 40.3 0.0 5.7e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family pKID PF02173.17 OWF50005.1 - 0.00056 19.3 0.0 13 5.3 0.0 4.5 4 1 1 5 5 5 2 pKID domain HTH_32 PF13565.6 OWF50005.1 - 0.0042 17.7 0.4 1.5 9.5 0.1 2.4 1 1 1 2 2 2 2 Homeodomain-like domain PBECR3 PF18812.1 OWF50005.1 - 0.0088 16.0 0.1 0.15 12.1 0.0 2.4 1 1 1 2 2 2 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Cdc6_C PF09079.11 OWF50005.1 - 0.072 13.1 0.5 3.1 7.9 0.1 2.6 1 1 2 3 3 3 0 CDC6, C terminal winged helix domain DUF2972 PF11186.8 OWF50005.1 - 0.077 12.9 0.0 3.7 7.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) zf-MYST PF17772.1 OWF50005.1 - 0.11 12.1 2.8 4 7.1 0.1 2.6 2 1 1 3 3 3 0 MYST family zinc finger domain Ank_2 PF12796.7 OWF50006.1 - 7.4e-09 36.1 0.1 0.0022 18.6 0.0 4.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50006.1 - 5.6e-08 33.2 1.0 0.00021 21.8 0.3 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) UvrD-helicase PF00580.21 OWF50006.1 - 2.8e-07 30.4 0.7 2.8e-07 30.4 0.7 6.8 7 1 1 8 8 8 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 OWF50006.1 - 1.8e-05 25.1 0.1 0.0021 18.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 OWF50006.1 - 6.7e-05 22.6 0.0 0.25 11.2 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Clathrin PF00637.20 OWF50006.1 - 0.00032 20.6 1.6 0.0099 15.8 0.2 3.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Ank PF00023.30 OWF50006.1 - 0.038 14.5 0.3 14 6.3 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ank_3 PF13606.6 OWF50006.1 - 0.16 12.6 0.2 4e+02 2.2 0.0 5.1 5 0 0 5 5 5 0 Ankyrin repeat AAA_22 PF13401.6 OWF50006.1 - 0.31 11.3 3.2 18 5.6 0.0 5.0 5 0 0 5 5 5 0 AAA domain MFS_1 PF07690.16 OWF50007.1 - 6.3e-26 91.1 37.8 3e-21 75.7 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SEA PF01390.20 OWF50008.1 - 4e-05 23.7 0.1 9.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 SEA domain Orthoreo_P10 PF07204.11 OWF50008.1 - 0.017 15.0 0.2 0.036 14.0 0.2 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 OWF50008.1 - 0.02 15.7 0.0 0.043 14.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF50008.1 - 0.029 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 OWF50008.1 - 0.04 13.9 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Protocadherin S_locus_glycop PF00954.20 OWF50008.1 - 0.071 13.6 15.0 3.8 8.1 6.2 2.6 1 1 1 2 2 2 0 S-locus glycoprotein domain LST1 PF05083.13 OWF50008.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 LST-1 protein FGFR3_TM PF18123.1 OWF50008.1 - 1.3 8.6 8.1 2.3 7.8 8.1 1.4 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain zf-RING_UBOX PF13445.6 OWF50009.1 - 2.8e-11 43.3 8.4 2.8e-11 43.3 8.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF50009.1 - 3.3e-08 33.2 10.1 3.3e-08 33.2 10.1 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF50009.1 - 1.1e-07 32.0 9.0 1.1e-07 32.0 9.0 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF50009.1 - 4.1e-07 29.9 8.3 4.1e-07 29.9 8.3 2.6 3 0 0 3 3 1 1 zinc-RING finger domain zf-B_box PF00643.24 OWF50009.1 - 1.3e-06 28.5 5.7 1.3e-06 28.5 5.7 3.4 4 0 0 4 4 3 1 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF50009.1 - 1.4e-06 28.0 6.2 1.4e-06 28.0 6.2 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF50009.1 - 7.5e-06 26.0 11.6 7.5e-06 26.0 11.6 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF50009.1 - 1.7e-05 24.5 10.4 1.7e-05 24.5 10.4 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF3071 PF11268.8 OWF50009.1 - 0.0003 20.9 0.1 0.0089 16.1 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3071) Prok-RING_4 PF14447.6 OWF50009.1 - 0.0068 16.2 7.8 0.0068 16.2 7.8 2.9 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 PAM2 PF07145.15 OWF50009.1 - 0.0073 15.9 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DLP_helical PF18709.1 OWF50009.1 - 0.042 13.0 2.3 0.063 12.5 2.3 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain AAA_32 PF13654.6 OWF50009.1 - 0.11 11.2 1.2 0.17 10.7 1.2 1.1 1 0 0 1 1 1 0 AAA domain Osmo_CC PF08946.10 OWF50009.1 - 0.14 12.4 0.8 0.32 11.3 0.8 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Sgf11 PF08209.11 OWF50009.1 - 0.31 10.6 2.5 0.5 10.0 0.3 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF1664 PF07889.12 OWF50009.1 - 1.1 9.3 3.2 3.1 7.8 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tn7_TnsC_Int PF11426.8 OWF50010.1 - 0.057 13.6 0.4 0.18 12.0 0.4 1.8 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC Ndufs5 PF10200.9 OWF50010.1 - 0.14 12.5 0.5 0.27 11.5 0.5 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TB2_DP1_HVA22 PF03134.19 OWF50011.1 - 3.9e-29 100.4 5.7 3.9e-29 100.4 5.7 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Phage_term_smal PF05944.12 OWF50011.1 - 0.1 12.6 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Phage small terminase subunit MT0933_antitox PF14013.6 OWF50011.1 - 0.52 10.7 5.0 0.77 10.1 2.5 2.4 2 1 0 2 2 2 0 MT0933-like antitoxin protein zf-C3HC4 PF00097.25 OWF50012.1 - 1.2e-06 28.3 12.5 1.2e-06 28.3 12.5 3.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF50012.1 - 3.3e-05 23.9 25.5 0.0004 20.5 3.3 4.0 4 1 1 5 5 5 2 B-box zinc finger zf-RING_2 PF13639.6 OWF50012.1 - 0.00013 22.2 11.7 0.00013 22.2 11.7 3.7 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF50012.1 - 0.00037 20.4 12.9 0.00037 20.4 12.9 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF50012.1 - 0.0048 17.0 12.7 0.0048 17.0 12.7 4.0 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF50012.1 - 0.0088 16.0 11.3 0.0088 16.0 11.3 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF50013.1 - 5.8e-06 26.1 12.3 5.8e-06 26.1 12.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF50013.1 - 0.00029 20.8 11.8 0.00029 20.8 11.8 2.7 2 0 0 2 2 2 1 RING-type zinc-finger NHL PF01436.21 OWF50013.1 - 0.00044 20.1 0.2 0.22 11.6 0.0 3.3 2 0 0 2 2 2 1 NHL repeat zf-RING_2 PF13639.6 OWF50013.1 - 0.00067 19.9 11.9 0.00067 19.9 11.9 3.8 3 1 0 3 3 3 1 Ring finger domain zf-B_box PF00643.24 OWF50013.1 - 0.0017 18.5 3.4 0.0017 18.5 3.4 3.7 3 1 0 3 3 3 2 B-box zinc finger zf-RING_5 PF14634.6 OWF50013.1 - 0.0071 16.3 11.1 0.0071 16.3 11.1 3.8 3 0 0 3 3 3 1 zinc-RING finger domain Herpes_capsid PF06112.11 OWF50014.1 - 0.035 14.2 7.9 0.039 14.0 7.9 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RGCC PF15151.6 OWF50014.1 - 0.46 10.7 4.1 0.57 10.4 4.1 1.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family zf-C2H2 PF00096.26 OWF50016.1 - 0.00053 20.3 0.3 0.00053 20.3 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF50016.1 - 0.0026 18.4 5.6 0.0029 18.3 0.5 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF50016.1 - 0.052 13.9 2.7 0.65 10.3 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-UBP PF02148.19 OWF50016.1 - 4.5 7.7 10.7 0.25 11.7 3.5 2.5 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein BB_PF PF18063.1 OWF50017.1 - 0.051 13.2 6.2 0.87 9.1 0.1 3.2 1 1 1 3 3 3 0 Beta barrel Pore-forming domain DUF4964 PF16334.5 OWF50017.1 - 0.55 9.8 5.4 5 6.7 0.0 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4964) Glyco_hydro_cc PF11790.8 OWF50018.1 - 1.9 8.0 4.8 5.3 6.5 2.6 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase catalytic core Fe-S_assembly PF04384.13 OWF50019.1 - 0.011 16.4 0.1 0.018 15.6 0.1 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly DUF4420 PF14390.6 OWF50019.1 - 0.061 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) DUF4881 PF16222.5 OWF50020.1 - 3.2 7.5 3.9 26 4.6 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4881) Thyroglobulin_1 PF00086.18 OWF50021.1 - 1.3e-15 56.8 6.7 1.4e-08 34.2 0.0 2.3 1 1 1 2 2 2 2 Thyroglobulin type-1 repeat Thyroglobulin_1 PF00086.18 OWF50022.1 - 1.8e-13 49.9 9.2 1.3e-06 28.0 1.5 2.3 1 1 1 2 2 2 2 Thyroglobulin type-1 repeat BTB PF00651.31 OWF50023.1 - 2.4e-11 43.8 0.2 2.4e-09 37.4 0.0 2.9 2 1 1 3 3 3 2 BTB/POZ domain BTB PF00651.31 OWF50024.1 - 4.8e-08 33.2 0.1 2e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 OWF50025.1 - 7.2e-06 26.2 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Striatin PF08232.12 OWF50026.1 - 0.0035 17.9 2.0 0.0041 17.7 2.0 1.1 1 0 0 1 1 1 1 Striatin family BTB PF00651.31 OWF50027.1 - 1.1e-10 41.8 0.0 2.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF50028.1 - 5.8e-11 42.6 0.1 2.7e-10 40.5 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain SL4P PF17618.2 OWF50028.1 - 0.079 13.0 0.4 5.4 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein SusD-like_3 PF14322.6 OWF50028.1 - 0.085 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane TAFH PF07531.14 OWF50028.1 - 0.14 12.2 0.0 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 NHR1 homology to TAF Nup54 PF13874.6 OWF50029.1 - 3.3e-07 30.5 5.8 1.1e-05 25.5 3.7 2.2 1 1 1 2 2 2 2 Nucleoporin complex subunit 54 Sec34 PF04136.15 OWF50029.1 - 1.4e-06 28.2 2.3 0.012 15.5 0.5 2.4 1 1 1 2 2 2 2 Sec34-like family EzrA PF06160.12 OWF50029.1 - 1.8e-06 26.5 14.3 5.5e-06 24.8 13.9 1.6 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA RmuC PF02646.16 OWF50029.1 - 3.8e-06 26.3 2.2 0.00087 18.5 0.4 2.2 1 1 1 2 2 2 2 RmuC family Spc7 PF08317.11 OWF50029.1 - 4.5e-06 25.8 1.1 6.3e-06 25.3 1.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein MscS_porin PF12795.7 OWF50029.1 - 3.3e-05 23.5 0.1 0.044 13.3 0.3 2.1 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain GAS PF13851.6 OWF50029.1 - 5.5e-05 22.6 6.1 0.0011 18.4 1.2 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding OmpH PF03938.14 OWF50029.1 - 6.4e-05 23.3 1.3 0.00046 20.5 1.3 2.3 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Mod_r PF07200.13 OWF50029.1 - 7e-05 23.0 6.9 0.25 11.4 1.0 3.2 1 1 2 3 3 3 1 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.9 OWF50029.1 - 7e-05 23.1 10.1 0.084 13.2 0.9 3.3 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 OWF50029.1 - 0.00015 20.5 7.3 0.00051 18.8 6.3 1.8 1 1 1 2 2 2 2 Flagellar Assembly Protein A SKA2 PF16740.5 OWF50029.1 - 0.00024 20.9 0.2 1.8 8.4 0.1 3.6 1 1 2 3 3 3 1 Spindle and kinetochore-associated protein 2 IFT57 PF10498.9 OWF50029.1 - 0.00031 19.8 15.2 0.015 14.3 9.3 2.1 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Syntaxin-6_N PF09177.11 OWF50029.1 - 0.00044 20.8 3.8 0.12 12.9 0.3 2.3 1 1 1 2 2 2 2 Syntaxin 6, N-terminal DUF5344 PF17279.2 OWF50029.1 - 0.00044 20.8 11.8 0.19 12.3 4.1 4.6 1 1 3 4 4 4 1 Family of unknown function (DUF5344) SOAR PF16533.5 OWF50029.1 - 0.00045 20.2 6.2 2.5 8.1 0.2 4.0 1 1 3 4 4 4 0 STIM1 Orai1-activating region TMPIT PF07851.13 OWF50029.1 - 0.00059 19.2 2.2 0.00077 18.8 2.2 1.3 1 0 0 1 1 1 1 TMPIT-like protein DUF1664 PF07889.12 OWF50029.1 - 0.00061 19.8 0.0 0.34 11.0 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) COG6 PF06419.11 OWF50029.1 - 0.001 17.4 1.1 0.44 8.7 0.1 2.3 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 TetR PF13972.6 OWF50029.1 - 0.0011 18.7 8.3 3.7 7.2 0.8 4.3 1 1 2 3 3 3 0 Bacterial transcriptional repressor ALIX_LYPXL_bnd PF13949.6 OWF50029.1 - 0.0014 18.0 11.7 0.0054 16.1 6.4 2.4 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV FliD_N PF02465.18 OWF50029.1 - 0.0014 19.3 0.4 1.8 9.3 0.1 2.9 1 1 2 3 3 2 0 Flagellar hook-associated protein 2 N-terminus APG17 PF04108.12 OWF50029.1 - 0.0015 17.7 12.6 0.0024 17.0 11.2 1.8 1 1 1 2 2 2 1 Autophagy protein Apg17 WXG100 PF06013.12 OWF50029.1 - 0.0016 18.7 0.0 0.015 15.5 0.0 2.3 1 1 0 1 1 1 1 Proteins of 100 residues with WXG PI_PP_I PF18363.1 OWF50029.1 - 0.0016 18.6 0.1 0.42 10.8 0.0 2.7 1 1 2 3 3 3 2 Phosphoinositide phosphatase insertion domain DUF4472 PF14739.6 OWF50029.1 - 0.0018 19.0 3.3 0.38 11.5 1.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4472) DUF349 PF03993.12 OWF50029.1 - 0.0026 18.0 0.6 0.093 13.0 0.6 3.1 1 1 3 4 4 4 1 Domain of Unknown Function (DUF349) DUF573 PF04504.14 OWF50029.1 - 0.0029 18.2 6.2 2.9 8.6 1.2 3.4 1 1 2 3 3 3 0 Protein of unknown function, DUF573 TMF_TATA_bd PF12325.8 OWF50029.1 - 0.0031 17.7 4.1 0.18 12.0 1.9 3.0 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Syntaxin PF00804.25 OWF50029.1 - 0.0034 17.1 6.1 0.0093 15.7 5.9 1.9 1 1 0 1 1 1 1 Syntaxin Jnk-SapK_ap_N PF09744.9 OWF50029.1 - 0.0035 17.6 6.5 0.017 15.3 5.7 2.2 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 YabA PF06156.13 OWF50029.1 - 0.0039 17.8 4.9 0.56 10.9 2.5 2.3 1 1 1 2 2 2 2 Initiation control protein YabA Laminin_II PF06009.12 OWF50029.1 - 0.004 17.2 0.1 2.3 8.2 0.1 2.6 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 OWF50029.1 - 0.0044 17.1 3.4 0.17 12.0 0.5 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 OWF50029.1 - 0.0046 16.7 9.1 0.0068 16.2 9.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Atg14 PF10186.9 OWF50029.1 - 0.0058 15.8 6.2 0.0071 15.5 6.2 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BicD PF09730.9 OWF50029.1 - 0.0061 15.1 9.3 0.034 12.6 1.8 2.1 1 1 1 2 2 2 2 Microtubule-associated protein Bicaudal-D Fez1 PF06818.15 OWF50029.1 - 0.0079 16.7 2.5 0.019 15.4 2.5 1.6 1 1 0 1 1 1 1 Fez1 DUF745 PF05335.13 OWF50029.1 - 0.0087 15.8 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) CREPT PF16566.5 OWF50029.1 - 0.0091 16.2 8.0 0.79 9.9 1.8 2.8 1 1 1 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour Lipoprotein_7 PF01540.16 OWF50029.1 - 0.0091 15.3 0.3 0.19 11.0 0.2 1.9 1 1 1 2 2 2 1 Adhesin lipoprotein DUF3552 PF12072.8 OWF50029.1 - 0.0096 15.4 2.9 0.016 14.7 2.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) DUF3543 PF12063.8 OWF50029.1 - 0.01 15.3 9.0 1.1 8.6 0.5 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3543) DUF2203 PF09969.9 OWF50029.1 - 0.011 16.4 2.7 0.12 13.1 2.7 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FPP PF05911.11 OWF50029.1 - 0.012 13.8 1.0 0.013 13.7 1.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil KxDL PF10241.9 OWF50029.1 - 0.013 15.7 2.0 2.6 8.4 0.3 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein PI3K_P85_iSH2 PF16454.5 OWF50029.1 - 0.013 15.0 13.7 2.7 7.6 4.0 3.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Vps5 PF09325.10 OWF50029.1 - 0.014 14.9 3.1 0.38 10.3 0.6 2.6 1 1 2 3 3 3 0 Vps5 C terminal like Lge1 PF11488.8 OWF50029.1 - 0.015 15.5 6.9 6.4 7.0 2.6 4.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Tup_N PF08581.10 OWF50029.1 - 0.016 15.5 19.6 0.58 10.5 10.7 3.2 1 1 2 3 3 3 0 Tup N-terminal Occludin_ELL PF07303.13 OWF50029.1 - 0.018 15.8 20.9 0.079 13.7 9.1 2.8 1 1 2 3 3 3 0 Occludin homology domain Myb_DNA-bind_3 PF12776.7 OWF50029.1 - 0.019 16.0 11.7 4.8e+02 1.8 11.7 3.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Syntaxin_2 PF14523.6 OWF50029.1 - 0.02 15.2 5.7 0.26 11.7 5.2 2.6 1 1 1 2 2 2 0 Syntaxin-like protein DUF2959 PF11172.8 OWF50029.1 - 0.024 14.8 11.6 0.084 13.0 8.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) TPR_12 PF13424.6 OWF50029.1 - 0.033 14.5 6.1 0.6 10.4 2.3 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 OWF50029.1 - 0.036 14.0 2.8 4.3 7.4 0.3 2.8 1 1 2 3 3 3 0 Prefoldin subunit Macoilin PF09726.9 OWF50029.1 - 0.036 12.6 5.3 0.085 11.4 5.2 1.6 1 1 0 1 1 1 0 Macoilin family DUF4200 PF13863.6 OWF50029.1 - 0.041 14.3 5.0 0.068 13.6 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) LPD39 PF18858.1 OWF50029.1 - 0.049 13.7 14.3 2.7e+02 1.5 13.7 3.4 1 1 1 2 2 1 0 Large polyvalent protein associated domain 39 ECM11 PF15463.6 OWF50029.1 - 0.059 14.0 4.8 5.4 7.6 2.3 3.1 1 1 1 2 2 2 0 Extracellular mutant protein 11 DUF724 PF05266.14 OWF50029.1 - 0.069 13.0 1.2 0.093 12.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.13 OWF50029.1 - 0.07 13.5 0.3 0.26 11.6 0.5 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region KELK PF15796.5 OWF50029.1 - 0.08 13.4 9.4 0.4 11.2 3.0 3.5 2 1 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ING PF12998.7 OWF50029.1 - 0.085 13.5 9.9 0.058 14.0 4.5 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4407 PF14362.6 OWF50029.1 - 0.085 12.2 2.1 0.27 10.6 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FH2 PF02181.23 OWF50029.1 - 0.089 11.9 2.5 4.1 6.4 0.2 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain NBD94 PF16830.5 OWF50029.1 - 0.11 12.9 14.0 1.6e+03 -0.4 13.1 3.9 1 1 1 2 2 1 0 Nucleotide-Binding Domain 94 of RH DUF4527 PF15030.6 OWF50029.1 - 0.11 11.9 0.1 10 5.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) MCPsignal PF00015.21 OWF50029.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Exonuc_VII_L PF02601.15 OWF50029.1 - 0.11 12.0 4.4 0.14 11.7 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit STAT_alpha PF01017.20 OWF50029.1 - 0.14 12.1 5.8 0.2 11.5 5.4 1.6 1 1 1 2 2 1 0 STAT protein, all-alpha domain zf-C4H2 PF10146.9 OWF50029.1 - 0.15 12.3 6.7 0.23 11.8 6.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Nmad5 PF18757.1 OWF50029.1 - 0.16 12.2 2.9 0.45 10.7 2.9 2.0 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 CheZ PF04344.13 OWF50029.1 - 0.17 11.7 0.2 2.8 7.8 0.2 2.0 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ HAUS6_N PF14661.6 OWF50029.1 - 0.18 11.3 10.3 1.2 8.7 2.9 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HAUS4 PF14735.6 OWF50029.1 - 0.2 11.3 11.1 0.78 9.4 4.0 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 4 Fib_alpha PF08702.10 OWF50029.1 - 0.2 11.8 9.7 0.41 10.8 9.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SLATT_6 PF18169.1 OWF50029.1 - 0.22 11.1 12.4 25 4.4 12.4 2.8 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 HAUS-augmin3 PF14932.6 OWF50029.1 - 0.23 11.0 3.4 0.8 9.2 2.2 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 HalX PF08663.10 OWF50029.1 - 0.25 11.7 4.8 0.87 10.0 1.1 3.0 1 1 2 3 3 3 0 HalX domain GH97_N PF14508.6 OWF50029.1 - 0.29 10.6 11.4 4 6.9 1.0 3.3 1 1 2 3 3 3 0 Glycosyl-hydrolase 97 N-terminal Dynactin_p22 PF07426.11 OWF50029.1 - 0.39 10.6 12.9 3.4 7.5 2.8 3.8 1 1 3 4 4 4 0 Dynactin subunit p22 ZapB PF06005.12 OWF50029.1 - 0.44 11.0 4.5 3.2 8.2 1.0 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF1409 PF07197.12 OWF50029.1 - 0.47 10.4 23.1 17 5.4 0.1 7.1 1 1 7 8 8 6 0 Protein of unknown function (DUF1409) HMMR_N PF15905.5 OWF50029.1 - 0.56 9.6 3.7 0.66 9.4 3.7 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Lipid_DES PF08557.10 OWF50029.1 - 0.65 9.5 5.2 31 4.2 0.0 4.4 4 1 3 7 7 5 0 Sphingolipid Delta4-desaturase (DES) FliD_C PF07195.12 OWF50029.1 - 0.86 9.0 8.4 2.2 7.6 1.9 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus AI-2E_transport PF01594.16 OWF50029.1 - 0.94 8.6 2.0 8.6 5.4 2.0 2.1 1 1 0 1 1 1 0 AI-2E family transporter CorA PF01544.18 OWF50029.1 - 1.1 8.5 6.8 1.3 8.3 6.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SHE3 PF17078.5 OWF50029.1 - 1.2 8.8 18.3 5.4 6.7 18.1 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CotJB PF12652.7 OWF50029.1 - 1.5 9.1 16.2 58 4.0 2.4 4.9 1 1 1 2 2 1 0 CotJB protein Trigger_C PF05698.14 OWF50029.1 - 1.6 8.7 7.3 34 4.4 0.5 3.3 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus DUF410 PF04190.13 OWF50029.1 - 1.7 8.4 5.8 3.2 7.5 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF410) Alpha-2-MRAP_C PF06401.11 OWF50029.1 - 1.9 8.4 11.6 7 6.6 2.7 2.2 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain YkyA PF10368.9 OWF50029.1 - 2.1 8.0 14.5 8.6 6.0 14.5 2.1 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein HOCHOB PF17943.1 OWF50029.1 - 2.9 8.6 15.8 2.2e+03 -0.7 15.4 3.6 1 1 0 1 1 0 0 Homeobox-cysteine loop-homeobox FliJ PF02050.16 OWF50029.1 - 3.7 7.8 12.5 11 6.2 10.7 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein DUF5486 PF17588.2 OWF50029.1 - 4.8 7.1 39.3 0.55 10.2 1.2 6.8 1 1 6 7 7 7 0 Family of unknown function (DUF5486) DUF3800 PF12686.7 OWF50029.1 - 5 7.8 9.7 1.5e+02 3.0 9.7 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4047 PF13256.6 OWF50029.1 - 8.9 6.5 14.3 14 5.9 4.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) PX PF00787.24 OWF50030.1 - 3.9e-12 46.2 0.4 9.1e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 PX domain CobT PF06213.12 OWF50030.1 - 0.0081 15.6 4.0 0.013 14.9 4.0 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Claudin_2 PF13903.6 OWF50031.1 - 1.5e-13 50.9 11.6 2.4e-13 50.3 11.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF50031.1 - 0.00032 20.7 15.0 0.014 15.3 15.8 2.2 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 OWF50031.1 - 0.00042 20.2 10.8 0.0049 16.8 1.8 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family GSG-1 PF07803.11 OWF50031.1 - 0.029 14.3 1.2 0.72 9.8 0.1 2.3 2 0 0 2 2 2 0 GSG1-like protein DUF4271 PF14093.6 OWF50031.1 - 0.06 13.2 13.2 0.19 11.6 7.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) EamA PF00892.20 OWF50031.1 - 1.2 9.3 16.6 1.7 8.8 10.8 2.7 2 1 1 3 3 3 0 EamA-like transporter family Zip PF02535.22 OWF50031.1 - 1.8 7.7 4.2 0.36 10.0 0.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter MARVEL PF01284.23 OWF50031.1 - 4.1 7.4 15.0 2.9 7.9 9.4 2.3 2 1 0 2 2 2 0 Membrane-associating domain Fibrinogen_C PF00147.18 OWF50032.1 - 2.3e-42 145.3 2.0 2.7e-42 145.1 2.0 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PI3_PI4_kinase PF00454.27 OWF50033.1 - 1.3e-34 120.2 3.1 1.6e-25 90.4 0.1 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OWF50033.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF4797 PF16051.5 OWF50033.1 - 5.7 7.0 12.6 0.33 10.9 2.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) V-SNARE_C PF12352.8 OWF50034.1 - 5.9e-17 61.7 2.5 2.2e-16 59.9 1.9 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OWF50034.1 - 1e-06 28.6 0.2 3.4e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 Sec20 Syntaxin_2 PF14523.6 OWF50034.1 - 0.035 14.5 3.3 0.54 10.7 0.2 2.7 2 1 1 3 3 3 0 Syntaxin-like protein HTH_Tnp_Tc5 PF03221.16 OWF50035.1 - 9.7e-15 54.4 0.1 2.9e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Bromodomain PF00439.25 OWF50035.1 - 5.6e-12 45.6 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 OWF50035.1 - 1.3e-09 38.3 0.4 2.4e-08 34.2 0.1 3.4 2 0 0 2 2 2 1 PWWP domain BrkDBD PF09607.10 OWF50035.1 - 2.7e-07 30.3 0.2 8.1e-07 28.7 0.2 1.8 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_psq PF05225.16 OWF50035.1 - 1.4e-06 27.9 0.1 3e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain PHD PF00628.29 OWF50035.1 - 1.1e-05 25.3 13.2 1.1e-05 25.3 13.2 2.8 3 0 0 3 3 3 1 PHD-finger CENP-B_N PF04218.13 OWF50035.1 - 0.00069 19.2 0.0 0.0038 16.8 0.0 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain zf-MYND PF01753.18 OWF50035.1 - 0.0011 19.0 14.5 0.0011 19.0 14.5 3.3 3 1 0 3 3 3 1 MYND finger HTH_Tnp_1 PF01527.20 OWF50035.1 - 0.0073 16.6 2.6 0.14 12.5 0.1 3.8 3 0 0 3 3 3 1 Transposase Cornifin PF02389.15 OWF50036.1 - 4e-30 104.8 13.0 1.4e-16 60.9 0.8 2.2 1 1 1 2 2 2 2 Cornifin (SPRR) family AraC_binding_2 PF14525.6 OWF50036.1 - 0.0002 21.1 6.9 4.3 7.0 0.4 4.5 1 1 4 5 5 5 4 AraC-binding-like domain B_solenoid_ydck PF18836.1 OWF50036.1 - 0.025 14.4 0.0 55 3.9 0.0 3.8 3 0 0 3 3 3 0 Beta solenoid repeat from YDCK DUF3432 PF11914.8 OWF50036.1 - 3.1 8.1 18.4 3.2 8.1 1.2 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF3432) Otopetrin PF03189.13 OWF50037.1 - 4.7e-111 371.8 12.0 4.7e-111 371.8 12.0 1.5 2 0 0 2 2 2 1 Otopetrin DUF2207 PF09972.9 OWF50037.1 - 0.0029 16.5 0.3 0.049 12.4 0.0 2.2 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF3784 PF12650.7 OWF50037.1 - 4.2 7.6 12.6 0.046 13.9 1.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) HlyIII PF03006.20 OWF50037.1 - 9.9 5.8 17.5 0.22 11.2 0.9 3.4 2 1 0 2 2 2 0 Haemolysin-III related OATP PF03137.20 OWF50039.1 - 2.5e-104 349.5 11.4 3e-104 349.3 11.4 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF50039.1 - 5.1e-15 55.3 27.6 2.7e-14 52.8 27.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF50039.1 - 0.00014 21.9 9.3 0.00029 20.9 9.3 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF50039.1 - 0.032 14.2 8.6 0.068 13.2 8.6 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain MFS_1 PF07690.16 OWF50040.1 - 6.4e-11 41.8 11.5 9.1e-11 41.3 11.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 OWF50040.1 - 1.1 9.6 9.7 0.12 12.7 3.7 2.5 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V MFS_1 PF07690.16 OWF50041.1 - 1.9e-31 109.3 25.9 5.2e-30 104.6 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VCBS PF13517.6 OWF50042.1 - 1.5e-24 86.3 30.6 1.8e-11 44.4 4.1 5.7 4 2 3 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 OWF50042.1 - 5.2e-12 45.5 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 OWF50042.1 - 4.9e-06 26.6 25.3 0.036 14.2 0.1 6.0 6 0 0 6 6 6 3 FG-GAP repeat PA PF02225.22 OWF50042.1 - 0.00038 20.4 0.0 0.00084 19.3 0.0 1.5 1 0 0 1 1 1 1 PA domain Dockerin_1 PF00404.18 OWF50042.1 - 0.62 10.3 6.4 68 3.8 0.1 4.3 4 0 0 4 4 4 0 Dockerin type I domain VCBS PF13517.6 OWF50043.1 - 2.9e-31 107.9 3.2 2.9e-09 37.4 0.2 4.6 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OWF50043.1 - 9.7e-17 60.8 12.2 0.00075 19.6 0.2 5.8 6 0 0 6 6 6 5 FG-GAP repeat UnbV_ASPIC PF07593.12 OWF50043.1 - 2.5e-12 46.6 0.2 8.3e-12 44.9 0.2 1.9 1 0 0 1 1 1 1 ASPIC and UnbV SWM_repeat PF13753.6 OWF50043.1 - 0.028 14.6 0.1 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 Putative flagellar system-associated repeat FAM167 PF11652.8 OWF50044.1 - 4.8e-23 81.4 0.6 4.8e-23 81.4 0.6 2.0 2 1 1 3 3 3 1 FAM167 Med30 PF11315.8 OWF50044.1 - 0.0035 17.6 1.7 0.006 16.8 1.7 1.4 1 0 0 1 1 1 1 Mediator complex subunit 30 ZIP4_domain PF18292.1 OWF50044.1 - 0.012 15.5 0.2 0.015 15.2 0.2 1.2 1 0 0 1 1 1 0 Zinc transporter ZIP4 domain NACHT_N PF17100.5 OWF50044.1 - 0.028 14.3 0.3 0.033 14.0 0.3 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase FlxA PF14282.6 OWF50044.1 - 0.056 13.4 4.8 0.094 12.7 4.8 1.3 1 0 0 1 1 1 0 FlxA-like protein ELH PF02323.15 OWF50045.1 - 1.7e-11 44.0 3.0 2.5e-05 23.8 0.2 2.2 2 0 0 2 2 2 2 Egg-laying hormone precursor 7tm_1 PF00001.21 OWF50048.1 - 5.3e-21 75.1 11.3 6.2e-21 74.9 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF50048.1 - 0.0046 16.7 15.5 0.009 15.8 15.1 1.5 1 1 0 1 1 1 1 Olfactory receptor OATP PF03137.20 OWF50049.1 - 2e-127 425.8 17.1 2.4e-127 425.5 17.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF50049.1 - 3e-13 49.5 32.0 1.3e-10 40.8 6.9 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF50049.1 - 1.5e-06 28.3 7.1 1.5e-06 28.3 7.1 2.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF50049.1 - 0.097 12.7 6.8 0.053 13.5 2.1 2.6 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain FAD_binding_2 PF00890.24 OWF50050.1 - 3.5e-126 421.7 1.5 4.8e-126 421.2 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OWF50050.1 - 7.6e-41 139.1 0.4 1.1e-40 138.5 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 OWF50050.1 - 1.3e-05 24.6 0.1 0.012 14.8 0.0 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 OWF50050.1 - 1.4e-05 24.4 1.2 0.0048 16.0 1.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OWF50050.1 - 2.3e-05 23.8 0.2 0.00029 20.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OWF50050.1 - 0.016 14.5 0.2 0.028 13.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OWF50050.1 - 0.042 13.4 0.3 0.091 12.3 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OWF50050.1 - 0.13 10.9 0.2 0.32 9.7 0.2 1.6 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 OWF50050.1 - 0.17 10.9 0.1 0.95 8.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Ank_2 PF12796.7 OWF50051.1 - 3.3e-44 149.4 12.7 3.5e-13 49.9 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF50051.1 - 3.3e-40 131.5 12.9 5.1e-07 29.5 0.1 9.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 OWF50051.1 - 4.6e-40 135.5 9.0 1.3e-10 41.6 0.2 6.8 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF50051.1 - 1e-34 118.1 8.8 4e-08 33.4 0.0 7.8 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF50051.1 - 1.1e-28 98.4 18.0 0.00012 22.4 0.0 8.5 8 0 0 8 8 8 8 Ankyrin repeat SOCS_box PF07525.16 OWF50051.1 - 8.4e-05 22.8 0.6 0.00016 21.9 0.6 1.5 1 0 0 1 1 1 1 SOCS box DUF249 PF03158.13 OWF50051.1 - 0.11 12.2 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 Multigene family 530 protein Amdo_NSP PF12475.8 OWF50051.1 - 0.24 11.5 1.3 8.9 6.5 0.1 3.6 4 0 0 4 4 4 0 Amdovirus non-structural protein zf-C2HC_2 PF13913.6 OWF50052.1 - 8.1e-10 38.4 13.9 6.5e-06 25.9 1.9 2.7 3 0 0 3 3 2 2 zinc-finger of a C2HC-type DZR PF12773.7 OWF50052.1 - 0.0017 18.4 13.2 0.11 12.5 2.9 3.5 3 0 0 3 3 3 2 Double zinc ribbon NinG PF05766.12 OWF50052.1 - 0.0029 17.6 5.6 0.0029 17.6 5.6 2.8 3 0 0 3 3 3 1 Bacteriophage Lambda NinG protein YacG PF03884.14 OWF50052.1 - 0.0049 16.6 4.8 0.31 10.8 0.4 2.7 2 0 0 2 2 2 2 DNA gyrase inhibitor YacG zf-CpG_bind_C PF12269.8 OWF50052.1 - 0.055 13.2 5.6 0.1 12.3 0.0 2.8 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain HypA PF01155.19 OWF50052.1 - 0.14 12.2 10.2 0.45 10.6 1.4 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 OWF50052.1 - 0.31 12.0 0.1 0.31 12.0 0.1 4.3 4 1 1 5 5 4 0 C2H2-type zinc finger zinc_ribbon_2 PF13240.6 OWF50052.1 - 0.35 10.6 22.1 0.58 10.0 9.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2 PF00096.26 OWF50052.1 - 0.67 10.5 0.1 0.67 10.5 0.1 4.5 5 0 0 5 5 4 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OWF50052.1 - 4 7.3 13.5 4.9 7.0 0.1 4.2 3 1 1 4 4 4 0 zinc-finger C2H2-type YhfH PF14149.6 OWF50052.1 - 4.2 7.4 10.5 42 4.2 0.0 4.1 4 0 0 4 4 4 0 YhfH-like protein DUF2318 PF10080.9 OWF50052.1 - 4.3 7.5 8.5 1.2 9.2 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) zinc_ribbon_9 PF14369.6 OWF50052.1 - 7.6 6.9 15.6 7 7.0 0.9 3.5 3 0 0 3 3 3 0 zinc-ribbon Yippee-Mis18 PF03226.14 OWF50053.1 - 0.00012 22.2 0.0 0.00031 20.9 0.0 1.6 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn-ribbon_8 PF09723.10 OWF50053.1 - 0.0077 16.3 0.2 1.5 9.0 0.1 2.5 2 1 0 2 2 2 1 Zinc ribbon domain Ogr_Delta PF04606.12 OWF50053.1 - 0.024 14.6 0.4 0.35 10.9 0.1 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.6 OWF50053.1 - 0.042 13.6 3.7 4.5 7.1 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 OWF50053.1 - 0.059 13.3 0.4 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 OWF50053.1 - 0.06 12.8 2.5 1.1 8.7 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.8 OWF50053.1 - 0.086 12.7 0.3 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Nudix_N_2 PF14803.6 OWF50053.1 - 0.1 12.6 1.5 8.9 6.3 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal DiS_P_DiS PF06750.13 OWF50053.1 - 0.11 12.6 0.0 9.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PhnA_Zn_Ribbon PF08274.12 OWF50053.1 - 0.15 12.0 0.7 7.4 6.6 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DNA_RNApol_7kD PF03604.13 OWF50053.1 - 0.16 11.6 1.8 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.6 OWF50053.1 - 2 8.5 4.2 3.8 7.6 0.9 2.3 2 0 0 2 2 2 0 YhfH-like protein DUF4772 PF15997.5 OWF50054.1 - 1.9e-28 99.4 0.0 7.8e-28 97.4 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4772) Tudor_3 PF18115.1 OWF50054.1 - 2.6e-06 27.2 0.0 5.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 OWF50054.1 - 3.3e-06 26.7 0.2 7.3e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_2 PF18104.1 OWF50054.1 - 0.00028 20.5 0.5 0.006 16.2 0.5 2.5 1 1 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain 53-BP1_Tudor PF09038.10 OWF50054.1 - 0.0032 17.4 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor DUF4537 PF15057.6 OWF50054.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) XendoU PF09412.10 OWF50055.1 - 1.8e-86 289.6 5.9 2.2e-86 289.3 5.9 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 OWF50055.1 - 0.055 13.8 1.6 0.14 12.5 0.1 2.2 2 1 0 2 2 2 0 Bacterial EndoU nuclease Pox_G7 PF05503.12 OWF50055.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like Forkhead PF00250.18 OWF50056.1 - 1.6e-22 79.6 0.5 3.3e-22 78.5 0.1 1.7 2 0 0 2 2 2 1 Forkhead domain Nodulin_late PF07127.11 OWF50057.1 - 1.3e-06 28.6 15.2 0.00079 19.7 1.8 2.1 2 0 0 2 2 2 2 Late nodulin protein WAP PF00095.21 OWF50057.1 - 0.94 9.9 22.4 2.4 8.6 7.6 2.5 1 1 1 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' EB PF01683.18 OWF50057.1 - 1.3 9.4 30.5 54 4.2 15.0 3.2 1 1 1 2 2 2 0 EB module Ureidogly_lyase PF04115.12 OWF50058.1 - 5.8e-10 39.3 0.0 1.5e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Ureidoglycolate lyase zf-C2H2_4 PF13894.6 OWF50059.1 - 7.9e-24 82.3 68.9 0.00081 20.0 0.2 10.9 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF50059.1 - 2.1e-18 65.7 78.9 0.00016 22.0 0.6 11.0 11 0 0 11 11 10 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF50059.1 - 1.9e-08 34.4 8.7 3.1e-05 24.2 3.5 10.2 11 0 0 11 11 10 5 Zinc-finger double domain zf-Di19 PF05605.12 OWF50059.1 - 0.00014 22.0 48.7 0.016 15.5 2.3 7.2 6 1 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 OWF50059.1 - 0.017 15.4 1.2 0.017 15.4 1.2 8.8 5 3 6 11 11 10 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OWF50059.1 - 0.025 14.3 0.2 0.025 14.3 0.2 6.4 6 0 0 6 6 6 0 zinc-finger C2H2-type zf_C2H2_13 PF18508.1 OWF50059.1 - 0.042 13.4 0.0 0.042 13.4 0.0 3.3 4 0 0 4 4 3 0 Zinc finger domain zf-C2H2_6 PF13912.6 OWF50059.1 - 0.084 12.9 0.3 0.084 12.9 0.3 8.8 11 0 0 11 11 11 0 C2H2-type zinc finger zf-met PF12874.7 OWF50059.1 - 0.15 12.5 0.1 0.15 12.5 0.1 8.9 10 0 0 10 10 9 0 Zinc-finger of C2H2 type zf_C2H2_6 PF18450.1 OWF50059.1 - 0.16 11.7 0.1 0.16 11.7 0.1 4.8 4 0 0 4 4 4 0 Zinc Finger domain zf-C2H2_9 PF16293.5 OWF50059.1 - 1.9 8.4 13.5 2.8 7.8 0.7 5.2 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) TRAF6_Z2 PF18048.1 OWF50059.1 - 5.1 7.3 6.8 20 5.4 0.0 3.7 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 PRP21_like_P PF12230.8 OWF50059.1 - 6.9 6.5 8.4 6.3 6.6 3.7 2.7 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_3rep PF18868.1 OWF50059.1 - 7.7 7.2 21.7 9.3 7.0 4.5 5.6 3 2 4 7 7 7 0 Zinc finger C2H2-type, 3 repeats Curlin_rpt PF07012.12 OWF50060.1 - 0.0029 17.6 8.4 3.5 7.7 0.7 4.7 2 2 2 4 4 4 3 Curlin associated repeat DUF5583 PF17821.1 OWF50060.1 - 0.0093 15.9 5.7 6 6.8 0.7 4.4 1 1 2 3 3 3 2 Family of unknown function (DUF5583) DUF3575 PF12099.8 OWF50060.1 - 0.021 14.1 0.4 2.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3575) DUF4634 PF15465.6 OWF50060.1 - 0.37 11.1 11.8 8.8 6.6 0.1 4.9 1 1 2 4 4 4 0 Domain of unknown function (DUF4634) UBX PF00789.20 OWF50061.1 - 1.6e-08 34.6 0.3 1.8e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 OWF50061.1 - 1.9e-08 34.0 0.2 3e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 OWF50061.1 - 0.00065 19.8 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like N6_Mtase PF02384.16 OWF50061.1 - 0.081 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 N-6 DNA Methylase TAP_C PF03943.13 OWF50061.1 - 0.12 12.1 0.1 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 TAP C-terminal domain DUF4670 PF15709.5 OWF50061.1 - 5.7 6.2 20.4 7.9 5.7 20.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) 7tm_2 PF00002.24 OWF50062.1 - 1.5e-19 70.3 21.5 2.2e-19 69.7 21.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF50062.1 - 8.3e-13 48.4 4.8 1.9e-12 47.3 4.8 1.6 1 0 0 1 1 1 1 Hormone receptor domain adh_short PF00106.25 OWF50063.1 - 2.8e-47 160.7 0.1 3.7e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50063.1 - 2.2e-32 112.5 0.0 3.2e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF50063.1 - 1.4e-09 38.1 0.0 2.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OWF50063.1 - 0.021 14.0 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_L30 PF00327.20 OWF50064.1 - 4.6e-19 68.0 0.7 1.9e-18 66.1 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 OWF50064.1 - 3.7e-05 23.9 0.0 7.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Neur_chan_LBD PF02931.23 OWF50065.1 - 7e-40 136.8 0.1 1.2e-39 136.0 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50065.1 - 1.2e-15 58.2 0.6 1.7e-15 57.7 0.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF50066.1 - 1.4e-45 155.4 0.2 1.9e-45 155.0 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50066.1 - 3.8e-18 66.4 0.2 5.8e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4064 PF13273.6 OWF50066.1 - 0.015 15.5 1.4 3.1 8.1 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Neur_chan_LBD PF02931.23 OWF50067.1 - 1.8e-45 155.1 0.1 2.7e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50067.1 - 7.4e-19 68.7 1.3 1.3e-18 68.0 0.8 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4446 PF14584.6 OWF50067.1 - 0.15 12.1 0.1 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DTC PF18102.1 OWF50068.1 - 6.3e-59 197.9 0.0 1.5e-58 196.6 0.0 1.7 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_2 PF13639.6 OWF50068.1 - 8e-08 32.5 10.7 2.7e-07 30.8 10.7 2.0 1 0 0 1 1 1 1 Ring finger domain Macro PF01661.21 OWF50068.1 - 1.2e-07 31.8 0.0 3.9e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Macro domain zf-C3HC4_2 PF13923.6 OWF50068.1 - 2.7e-07 30.3 11.5 6.1e-07 29.2 11.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF50068.1 - 3.5e-05 23.6 9.4 7.4e-05 22.5 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF50068.1 - 6.6e-05 22.8 10.1 0.00016 21.5 10.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF50068.1 - 0.00029 20.7 11.9 0.00029 20.7 11.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OWF50068.1 - 0.00056 19.7 3.7 0.0014 18.5 3.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 OWF50068.1 - 0.00062 19.7 6.0 0.00062 19.7 6.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 OWF50068.1 - 0.00079 19.7 7.5 0.0027 18.0 7.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF50068.1 - 0.048 13.8 6.5 0.13 12.4 6.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OWF50068.1 - 0.055 13.3 12.8 1.5 8.7 12.9 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF50068.1 - 0.066 13.0 8.5 0.18 11.5 8.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 OWF50068.1 - 0.13 12.5 10.3 0.34 11.1 10.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 OWF50068.1 - 0.33 10.9 6.2 0.77 9.7 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OWF50068.1 - 0.89 9.4 7.0 1.9 8.4 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA_21 PF13304.6 OWF50069.1 - 2.2 8.0 6.7 4.2 7.1 6.7 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system EF-hand_7 PF13499.6 OWF50070.1 - 1.4e-28 99.1 12.0 4e-15 56.0 1.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF50070.1 - 5.2e-27 91.3 15.2 7.6e-08 31.4 1.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF50070.1 - 5e-20 69.7 14.0 1.8e-05 24.3 0.9 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF50070.1 - 1.1e-17 63.6 16.7 1.2e-07 31.5 0.9 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF50070.1 - 5.7e-15 54.1 18.0 1.8e-05 24.0 0.9 4.6 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 OWF50070.1 - 2.7e-06 27.3 10.0 0.011 15.6 0.8 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF50070.1 - 5.4e-06 26.7 2.5 0.078 13.3 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OWF50070.1 - 5.1e-05 23.5 1.2 0.046 14.1 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain TerB PF05099.13 OWF50070.1 - 0.021 14.8 1.3 1.2 9.1 0.1 2.8 1 1 2 3 3 3 0 Tellurite resistance protein TerB EF-hand_10 PF14788.6 OWF50070.1 - 0.038 13.8 6.4 10 6.1 0.1 3.4 3 0 0 3 3 3 0 EF hand p25-alpha PF05517.12 OWF50070.1 - 0.11 12.6 6.7 0.26 11.4 2.0 2.3 1 1 1 2 2 2 0 p25-alpha Toprim_4 PF13662.6 OWF50070.1 - 0.12 12.9 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Caleosin PF05042.13 OWF50070.1 - 0.25 11.3 4.0 16 5.4 0.1 3.0 1 1 1 3 3 3 0 Caleosin related protein Ribophorin_II PF05817.14 OWF50071.1 - 3.9e-218 726.1 7.2 4.5e-218 725.9 7.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II TPD52 PF04201.15 OWF50072.1 - 1.5e-39 135.2 18.3 4.6e-21 75.1 6.9 2.9 1 1 1 2 2 2 2 Tumour protein D52 family Apo-CII PF05355.11 OWF50072.1 - 0.048 13.8 2.1 4.5 7.5 1.0 2.4 1 1 1 2 2 2 0 Apolipoprotein C-II Spore_III_AB PF09548.10 OWF50072.1 - 0.16 12.1 3.8 3.5 7.7 3.8 2.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DHquinase_II PF01220.19 OWF50072.1 - 0.41 10.3 2.7 4 7.1 1.4 2.2 1 1 1 2 2 2 0 Dehydroquinase class II RRM_1 PF00076.22 OWF50073.1 - 4.1e-17 61.8 0.6 6.2e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF50073.1 - 4.2e-06 26.4 0.0 4.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OWF50073.1 - 0.03 14.5 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain RRM_7 PF16367.5 OWF50073.1 - 0.037 14.2 0.3 0.17 12.1 0.3 2.1 1 1 0 1 1 1 0 RNA recognition motif DUF3791 PF12668.7 OWF50073.1 - 0.089 12.9 0.1 2.4 8.3 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3791) ApoO PF09769.9 OWF50074.1 - 0.099 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein O Bacteriocin_IIc PF10439.9 OWF50074.1 - 0.54 10.4 12.5 0.91 9.7 12.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide zf-Nse PF11789.8 OWF50075.1 - 7.2e-18 64.2 0.5 1.3e-17 63.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HrpJ PF07201.11 OWF50075.1 - 0.00021 21.6 0.4 0.00037 20.9 0.4 1.3 1 0 0 1 1 1 1 HrpJ-like domain zf-MIZ PF02891.20 OWF50075.1 - 0.00087 19.0 0.2 0.0028 17.4 0.2 1.9 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 OWF50075.1 - 0.026 14.5 0.1 0.065 13.3 0.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF4239 PF14023.6 OWF50075.1 - 0.031 14.0 0.3 0.041 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) zf-rbx1 PF12678.7 OWF50075.1 - 0.041 14.2 0.1 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain U-box PF04564.15 OWF50075.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_2 PF13639.6 OWF50075.1 - 0.058 13.7 0.2 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 Ring finger domain ACOX PF01756.19 OWF50076.1 - 1.3e-55 187.8 0.6 2.7e-55 186.7 0.4 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OWF50076.1 - 1.8e-28 99.6 0.1 1e-27 97.2 0.1 2.2 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OWF50076.1 - 5.5e-11 42.5 0.1 1.6e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OWF50076.1 - 1e-05 25.8 0.1 2.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OWF50076.1 - 3.9e-05 24.3 0.1 0.00035 21.2 0.0 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain DUF5063 PF16702.5 OWF50076.1 - 0.00044 20.7 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5063) HATPase_c_3 PF13589.6 OWF50077.1 - 5.5e-12 45.7 0.0 1.6e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_hinge PF06470.13 OWF50077.1 - 2.7e-09 37.3 0.0 6.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain HATPase_c PF02518.26 OWF50077.1 - 7.3e-05 23.2 0.0 0.00039 20.9 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF641 PF04859.12 OWF50077.1 - 0.25 11.7 2.5 0.99 9.7 2.5 2.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Big_1 PF02369.16 OWF50077.1 - 0.49 10.4 6.8 6.7 6.8 0.1 4.7 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 1) EGF PF00008.27 OWF50078.1 - 5.1e-06 26.7 8.9 5.1e-06 26.7 8.9 2.9 2 1 0 2 2 2 1 EGF-like domain hEGF PF12661.7 OWF50078.1 - 3.9e-05 24.1 5.7 3.9e-05 24.1 5.7 3.0 2 0 0 2 2 2 1 Human growth factor-like EGF CUB PF00431.20 OWF50078.1 - 0.00044 20.6 0.0 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 CUB domain EGF_2 PF07974.13 OWF50078.1 - 0.00059 20.1 8.8 0.00059 20.1 8.8 2.8 2 1 0 2 2 2 1 EGF-like domain Defensin_like PF10868.8 OWF50078.1 - 0.0029 18.3 8.2 0.0029 18.3 8.2 2.7 2 0 0 2 2 2 1 Cysteine-rich antifungal protein 2, defensin-like Fer4_23 PF18009.1 OWF50078.1 - 0.039 14.4 0.9 14 6.2 0.0 2.8 2 1 1 3 3 3 0 4Fe-4S iron-sulfur cluster binding domain MAM PF00629.23 OWF50079.1 - 1.4e-15 57.6 0.0 1.5e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Astacin PF01400.24 OWF50080.1 - 5e-31 107.8 1.7 9.5e-31 106.9 1.7 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF PF00008.27 OWF50080.1 - 1.1e-06 28.8 24.5 1.7e-06 28.2 8.2 3.3 2 1 0 2 2 2 1 EGF-like domain CUB PF00431.20 OWF50080.1 - 2e-05 24.9 0.0 4.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 CUB domain Defensin_like PF10868.8 OWF50080.1 - 0.0032 18.2 8.4 0.0032 18.2 8.4 3.0 3 0 0 3 3 3 1 Cysteine-rich antifungal protein 2, defensin-like hEGF PF12661.7 OWF50080.1 - 0.02 15.5 5.1 0.02 15.5 5.1 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF DUF45 PF01863.17 OWF50080.1 - 0.099 12.7 1.2 0.19 11.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 EGF_2 PF07974.13 OWF50080.1 - 0.1 13.0 28.9 0.044 14.2 9.7 3.2 2 1 0 2 2 2 0 EGF-like domain UPF0054 PF02130.17 OWF50080.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Dpy19 PF10034.9 OWF50081.1 - 7.3e-237 787.7 11.2 8.7e-237 787.5 11.2 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Macro PF01661.21 OWF50082.1 - 8.1e-51 171.0 1.1 3.9e-24 85.0 0.1 3.8 3 0 0 3 3 3 3 Macro domain PARP PF00644.20 OWF50082.1 - 4.6e-10 39.4 0.0 2.2e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain NID PF07292.13 OWF50082.1 - 4.5e-08 33.6 6.9 0.82 10.4 0.1 6.6 5 1 0 5 5 5 4 Nmi/IFP 35 domain (NID) RRM_occluded PF16842.5 OWF50082.1 - 3.3e-07 30.1 0.4 0.00052 19.8 0.1 3.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif WWE PF02825.20 OWF50082.1 - 3.7e-05 24.2 0.1 0.00018 22.0 0.1 2.3 1 0 0 1 1 1 1 WWE domain RRM_1 PF00076.22 OWF50082.1 - 0.00016 21.4 4.0 0.61 10.0 0.0 4.0 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2963 PF11178.8 OWF50082.1 - 0.047 13.4 1.7 0.24 11.1 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) ABC1 PF03109.16 OWF50083.1 - 1.4e-10 41.4 0.0 3.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family DUF2457 PF10446.9 OWF50083.1 - 0.021 14.0 2.2 0.034 13.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AMNp_N PF10423.9 OWF50083.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Pex14_N PF04695.13 OWF50083.1 - 0.082 13.6 6.1 0.21 12.2 6.1 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lipase_GDSL_2 PF13472.6 OWF50084.1 - 4.8e-07 30.3 0.0 5.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 OWF50084.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 OSK domain UPF0183 PF03676.14 OWF50085.1 - 5e-164 546.2 0.3 5.7e-164 546.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Not1 PF04054.15 OWF50086.1 - 8e-151 502.1 5.1 8e-151 502.1 5.1 3.3 4 0 0 4 4 4 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OWF50086.1 - 4.6e-93 310.7 1.2 4.6e-93 310.7 1.2 3.0 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OWF50086.1 - 5.7e-73 244.1 33.6 4.4e-70 234.7 31.6 3.4 2 1 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OWF50086.1 - 4.4e-53 179.4 0.0 4.4e-53 179.4 0.0 3.3 2 0 0 2 2 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3819 PF12842.7 OWF50086.1 - 9.3e-51 171.6 6.1 9.3e-51 171.6 6.1 3.2 2 0 0 2 2 1 1 Domain of unknown function (DUF3819) EPL1 PF10513.9 OWF50086.1 - 0.0021 18.5 2.0 0.0041 17.5 2.0 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like DDHD PF02862.17 OWF50086.1 - 0.034 14.3 4.9 0.087 13.0 4.9 1.6 1 0 0 1 1 1 0 DDHD domain DUF4820 PF16091.5 OWF50086.1 - 0.1 11.9 6.6 0.29 10.5 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AAA_23 PF13476.6 OWF50086.1 - 0.11 13.0 7.6 0.27 11.7 7.6 1.6 1 0 0 1 1 1 0 AAA domain SID-1_RNA_chan PF13965.6 OWF50086.1 - 0.16 10.3 1.0 0.25 9.7 1.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMR1 PF08505.10 OWF50086.1 - 0.19 12.0 16.2 0.54 10.5 16.2 1.7 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Lin-8 PF03353.15 OWF50086.1 - 0.23 11.0 15.5 0.68 9.4 15.5 1.8 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Suf PF05843.14 OWF50086.1 - 0.36 10.8 12.6 0.82 9.6 12.6 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 OWF50086.1 - 0.37 9.7 13.7 0.69 8.8 13.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 OWF50086.1 - 0.46 9.9 10.1 0.91 8.9 10.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 OWF50086.1 - 0.55 10.3 6.8 1.1 9.3 6.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 OWF50086.1 - 0.8 9.5 8.5 1.5 8.5 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRM13 PF05206.14 OWF50086.1 - 1 8.8 6.9 2.1 7.8 6.9 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF4770 PF15994.5 OWF50086.1 - 1.1 9.4 13.2 2.4 8.4 13.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) STAG PF08514.11 OWF50086.1 - 2.9 7.9 10.1 9.8 6.1 0.0 3.4 3 0 0 3 3 2 0 STAG domain Presenilin PF01080.17 OWF50086.1 - 3 6.5 13.0 5 5.8 13.0 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 OWF50086.1 - 3.6 7.1 41.8 9.2 5.8 41.8 1.6 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 OWF50086.1 - 4.1 7.4 19.2 9 6.3 19.2 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Hydin_ADK PF17213.3 OWF50086.1 - 4.5 7.5 10.3 12 6.1 10.3 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CPSF100_C PF13299.6 OWF50086.1 - 5.1 7.3 8.7 11 6.2 8.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.13 OWF50086.1 - 7.1 6.3 11.7 14 5.4 11.7 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF702 PF05142.12 OWF50086.1 - 9.7 6.7 15.4 26 5.3 15.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CUB PF00431.20 OWF50087.1 - 1.7e-11 44.4 0.0 2.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 OWF50087.1 - 2.5e-06 27.6 8.6 2.5e-06 27.6 8.6 1.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A EphA2_TM PF14575.6 OWF50087.1 - 0.0025 18.7 0.0 0.017 16.0 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 OWF50087.1 - 0.24 11.5 0.1 0.32 11.1 0.1 1.2 1 0 0 1 1 1 0 Podoplanin BTB_2 PF02214.22 OWF50088.1 - 1.1e-16 61.0 0.0 1.8e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LSM PF01423.22 OWF50089.1 - 2.5e-19 68.7 0.0 3.2e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sel1 PF08238.12 OWF50090.1 - 1.3e-11 44.8 5.8 2.1e-08 34.6 0.0 2.8 3 0 0 3 3 3 2 Sel1 repeat Robl_LC7 PF03259.17 OWF50091.1 - 7.7e-22 76.9 0.0 9.3e-22 76.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain UPF0176_N PF17773.1 OWF50091.1 - 0.0021 18.4 0.0 0.0028 18.0 0.0 1.1 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain LAMTOR5 PF16672.5 OWF50091.1 - 0.0046 16.9 0.0 0.0057 16.5 0.0 1.3 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 Metallophos PF00149.28 OWF50093.1 - 2e-10 41.5 0.0 5.2e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF50093.1 - 0.0049 17.1 0.0 0.0078 16.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acid_PPase PF12689.7 OWF50094.1 - 5.9e-53 179.2 0.0 7.3e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 OWF50094.1 - 3.2e-06 27.4 0.5 5e-05 23.5 0.0 2.2 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 OWF50094.1 - 0.035 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase IBR PF01485.21 OWF50095.1 - 3.1e-06 27.3 8.8 3.1e-06 27.3 8.8 2.4 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OWF50095.1 - 0.085 12.9 15.6 0.18 11.9 0.1 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 OWF50095.1 - 0.24 11.7 17.3 3.6 8.0 10.0 3.3 2 1 1 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 OWF50095.1 - 2.2 8.2 13.2 1 9.3 4.5 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF50095.1 - 3.2 7.7 14.8 14 5.6 0.2 3.5 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF50095.1 - 3.2 7.7 15.3 64 3.5 0.1 3.4 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NIP_1 PF08995.10 OWF50096.1 - 0.044 14.2 1.6 0.092 13.1 1.7 1.4 1 1 0 1 1 1 0 Necrosis inducing protein-1 IBR PF01485.21 OWF50099.1 - 1.4e-05 25.2 11.7 1.4e-05 25.2 11.7 2.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain p450 PF00067.22 OWF50100.1 - 9.8e-101 337.8 0.1 1.3e-100 337.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.28 OWF50101.1 - 7e-22 77.4 0.0 9.7e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1659 PF07872.11 OWF50102.1 - 1.4 8.6 43.5 3.9 7.2 0.3 10.8 6 5 7 13 13 13 0 Protein of unknown function (DUF1659) DUF753 PF05444.12 OWF50103.1 - 0.014 15.4 6.7 0.017 15.1 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF753) DUF359 PF04019.12 OWF50104.1 - 0.031 13.9 0.2 0.038 13.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF359) TPX2 PF06886.11 OWF50104.1 - 0.088 13.1 11.9 0.14 12.4 11.9 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) RGS PF00615.19 OWF50105.1 - 8.7e-31 106.6 5.5 1.1e-12 48.2 0.2 5.4 6 0 0 6 6 6 4 Regulator of G protein signaling domain IgGFc_binding PF17517.2 OWF50106.1 - 1e-48 166.1 14.2 2.6e-47 161.5 8.4 2.2 2 0 0 2 2 2 2 IgGFc binding protein PNP_UDP_1 PF01048.20 OWF50107.1 - 3.2e-50 170.6 0.6 3.9e-50 170.3 0.6 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 OWF50108.1 - 5.1e-16 58.6 0.1 5.6e-16 58.5 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily LLC1 PF14945.6 OWF50109.1 - 8.7e-43 145.7 3.9 9.8e-43 145.5 3.9 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.6 OWF50109.1 - 0.2 12.4 3.5 0.44 11.3 3.5 1.5 1 1 0 1 1 1 0 FAM183A and FAM183B related HSP70 PF00012.20 OWF50110.1 - 2.9e-261 867.9 5.0 3.3e-261 867.7 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF50110.1 - 4e-17 62.0 0.0 1.2e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OWF50110.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OWF50110.1 - 0.0013 19.1 1.3 6.5 7.2 0.0 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OWF50110.1 - 0.0082 15.4 0.3 0.052 12.8 0.1 2.3 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase HSP70 PF00012.20 OWF50111.1 - 1.3e-260 865.7 4.4 1.5e-260 865.6 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF50111.1 - 4.2e-17 62.0 0.0 1.3e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OWF50111.1 - 0.00061 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OWF50111.1 - 0.0015 19.0 1.2 6.4 7.2 0.0 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OWF50111.1 - 0.0097 15.2 0.4 0.052 12.8 0.1 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase LIM PF00412.22 OWF50112.1 - 5.9e-29 100.1 43.1 4.3e-12 46.1 9.0 3.4 3 0 0 3 3 3 3 LIM domain MORN PF02493.20 OWF50113.1 - 3.9e-40 133.4 45.9 2.5e-07 30.2 3.9 9.4 9 0 0 9 9 9 8 MORN repeat MG4 PF17789.1 OWF50113.1 - 0.031 14.4 0.0 0.087 13.0 0.0 1.8 1 0 0 1 1 1 0 Macroglobulin domain MG4 DUF3211 PF11485.8 OWF50113.1 - 0.082 13.1 0.6 0.32 11.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3211) CDC45 PF02724.14 OWF50113.1 - 0.74 8.0 4.7 1 7.6 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OWF50113.1 - 3.3 5.8 12.1 5.4 5.1 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family EF-hand_6 PF13405.6 OWF50114.1 - 4.5e-09 35.5 3.4 0.00012 21.7 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF50114.1 - 6e-09 34.8 3.2 7.8e-06 25.1 0.9 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF50114.1 - 8e-09 35.8 2.0 0.00084 19.7 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF50114.1 - 2e-08 33.9 2.0 0.00027 20.7 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF50114.1 - 3.5e-07 29.4 1.7 2.2e-06 26.9 0.7 2.6 2 0 0 2 2 2 1 EF hand ABM PF03992.16 OWF50114.1 - 0.0033 17.5 0.0 0.0096 16.0 0.0 1.8 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF2014 PF09427.10 OWF50114.1 - 0.014 14.8 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) PMT2_N PF17987.1 OWF50114.1 - 0.097 12.9 0.4 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoethanolamine N-methyltransferase 2 N-terminal EF-hand_10 PF14788.6 OWF50114.1 - 0.22 11.4 6.8 4.4 7.3 0.1 2.9 3 0 0 3 3 3 0 EF hand TINF2_N PF14973.6 OWF50116.1 - 4.5e-23 82.2 0.9 4.5e-23 82.2 0.9 1.8 2 0 0 2 2 2 1 TERF1-interacting nuclear factor 2 N-terminus RBP_receptor PF14752.6 OWF50117.1 - 1.7e-27 96.3 0.4 1.9e-27 96.1 0.4 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor KRTAP PF11759.8 OWF50118.1 - 0.013 16.0 5.3 4.5 7.9 5.3 2.8 1 1 0 1 1 1 0 Keratin-associated matrix Cuticle_3 PF11018.8 OWF50118.1 - 0.017 15.3 8.0 0.15 12.3 1.6 2.1 1 1 1 2 2 2 0 Pupal cuticle protein C1 Archaeal_AmoA PF12942.7 OWF50118.1 - 0.27 10.9 13.9 9.4 5.9 0.9 3.8 1 1 3 4 4 4 0 Archaeal ammonia monooxygenase subunit A (AmoA) Extensin_2 PF04554.13 OWF50118.1 - 2.2 8.4 30.6 0.26 11.4 9.8 3.0 1 1 1 2 2 2 0 Extensin-like region FAM47 PF14642.6 OWF50119.1 - 0.019 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 FAM47 family Drf_FH1 PF06346.12 OWF50119.1 - 0.019 14.7 8.7 0.022 14.5 8.7 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 FAM47 PF14642.6 OWF50120.1 - 3.8e-11 43.0 0.0 0.00026 20.6 0.0 3.0 1 1 2 3 3 3 3 FAM47 family Drf_FH1 PF06346.12 OWF50120.1 - 2.4e-06 27.4 43.0 0.00047 19.9 25.4 2.2 1 1 1 2 2 2 2 Formin Homology Region 1 RBP_receptor PF14752.6 OWF50121.1 - 8.2e-98 328.5 22.0 1.3e-97 327.9 22.0 1.2 1 0 0 1 1 1 1 Retinol binding protein receptor Orthoreo_P17 PF07272.11 OWF50121.1 - 0.2 11.7 2.1 0.24 11.4 0.6 1.8 2 0 0 2 2 2 0 Orthoreovirus P17 protein DUF1129 PF06570.11 OWF50121.1 - 9.2 5.7 8.8 2.2 7.7 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) 7tm_1 PF00001.21 OWF50122.1 - 7.3e-51 173.0 25.1 1.3e-50 172.2 20.2 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF50122.1 - 2.2e-10 40.4 18.2 3.1e-10 39.9 18.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF50122.1 - 8.7e-10 38.7 12.9 8.7e-10 38.7 12.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF50122.1 - 1.8e-07 31.2 13.3 1.3e-06 28.3 13.3 2.2 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 OWF50122.1 - 7.2e-06 25.5 19.3 1.5e-05 24.5 19.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TMEM154 PF15102.6 OWF50122.1 - 0.0064 16.4 0.6 0.09 12.7 0.1 2.3 2 0 0 2 2 2 1 TMEM154 protein family DUF3377 PF11857.8 OWF50122.1 - 0.078 12.9 3.3 0.087 12.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Anoctamin PF04547.12 OWF50123.1 - 2.7e-136 455.0 19.3 3.3e-136 454.7 19.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OWF50123.1 - 0.00019 21.3 0.2 0.00053 19.8 0.2 1.8 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Pyr_excise PF03013.14 OWF50123.1 - 0.1 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase LRR_8 PF13855.6 OWF50124.1 - 2.3e-50 168.2 51.4 5e-13 48.6 10.9 6.4 2 1 4 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 OWF50124.1 - 4.5e-23 81.6 19.9 4.5e-09 36.3 7.6 3.9 2 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF50124.1 - 9e-19 67.3 51.0 0.00025 21.4 1.1 8.3 5 2 3 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF50124.1 - 5.1e-11 42.4 15.1 5.9e-05 22.6 2.5 4.5 1 1 4 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 OWF50124.1 - 6.1e-07 29.1 52.9 1.8 9.4 0.1 12.2 12 1 1 13 13 13 5 Leucine Rich Repeat Rax2 PF12768.7 OWF50124.1 - 0.02 14.3 0.0 0.02 14.3 0.0 3.4 5 0 0 5 5 5 0 Cortical protein marker for cell polarity Sarcoglycan_2 PF05510.13 OWF50124.1 - 0.064 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF3744 PF12558.8 OWF50124.1 - 0.24 12.2 3.4 0.47 11.3 0.1 3.1 3 1 0 3 3 3 0 ATP-binding cassette cobalt transporter DUF1647 PF07801.11 OWF50124.1 - 0.45 10.3 3.4 2.7 7.8 0.1 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1647) LRR_6 PF13516.6 OWF50124.1 - 2.7 8.3 43.6 7 7.0 0.3 9.9 10 0 0 10 10 10 0 Leucine Rich repeat Acyl-ACP_TE PF01643.17 OWF50125.1 - 0.022 14.1 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF50125.1 - 0.076 13.5 0.4 0.33 11.4 0.1 1.9 2 0 0 2 2 2 0 Thioesterase-like superfamily 4HBT PF03061.22 OWF50125.1 - 0.14 12.5 0.0 1.2 9.6 0.0 2.2 2 1 0 2 2 2 0 Thioesterase superfamily Proteasome PF00227.26 OWF50126.1 - 1e-63 214.3 0.1 1.3e-63 213.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OWF50126.1 - 1.4e-14 53.4 0.2 2.7e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SSXT PF05030.12 OWF50127.1 - 4e-30 103.2 3.1 1e-29 102.0 3.1 1.7 1 0 0 1 1 1 1 SSXT protein (N-terminal region) NTF2 PF02136.20 OWF50128.1 - 8.1e-25 87.7 0.3 9.3e-25 87.5 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 OWF50128.1 - 0.0016 18.4 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 EnY2 PF10163.9 OWF50131.1 - 1.9e-35 121.1 0.9 2.2e-35 120.8 0.9 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2294 PF10057.9 OWF50131.1 - 0.017 15.2 0.5 0.28 11.3 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) Sin3a_C PF16879.5 OWF50131.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein E2F_CC-MB PF16421.5 OWF50132.1 - 2e-32 111.4 0.1 3.3e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 OWF50132.1 - 3.7e-24 84.6 0.2 7.1e-24 83.7 0.2 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Pil1 PF13805.6 OWF50132.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 ZapB PF06005.12 OWF50132.1 - 0.2 12.1 1.6 0.48 10.9 1.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB BTB PF00651.31 OWF50133.1 - 1.5e-20 73.5 0.1 3.5e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF50133.1 - 2.2e-15 56.6 2.7 2.9e-13 49.8 1.1 2.8 2 1 0 2 2 2 2 BTB And C-terminal Kelch gag_pre-integrs PF13976.6 OWF50133.1 - 8.5 6.3 8.1 4.7 7.1 0.0 3.8 4 0 0 4 4 4 0 GAG-pre-integrase domain Kinesin PF00225.23 OWF50134.1 - 2.8e-106 355.2 0.1 5.7e-106 354.2 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF50134.1 - 5.9e-22 78.2 6.5 9.5e-22 77.5 0.3 3.8 3 1 0 3 3 3 1 Microtubule binding Kinesin_assoc PF16183.5 OWF50134.1 - 5.2e-08 33.2 12.6 2.3e-05 24.6 1.2 4.2 3 1 1 4 4 4 2 Kinesin-associated FHA PF00498.26 OWF50134.1 - 7.2e-08 32.7 0.2 6.7e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 OWF50134.1 - 6.1e-07 29.8 0.4 2.1e-06 28.0 0.1 2.2 2 0 0 2 2 2 1 Kinesin protein 1B AAA_33 PF13671.6 OWF50134.1 - 0.024 14.8 0.0 0.098 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Choline_kinase PF01633.20 OWF50134.1 - 0.051 13.1 1.2 0.18 11.4 0.5 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF4790 PF16037.5 OWF50134.1 - 3.4 8.2 5.9 1.6 9.3 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) AA_permease PF00324.21 OWF50135.1 - 2.4e-58 197.9 43.6 1.2e-42 146.1 9.8 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 OWF50135.1 - 2e-29 102.9 0.1 4.5e-14 52.3 0.1 2.1 1 1 1 2 2 2 2 Solute carrier family 12 DUF4661 PF15576.6 OWF50136.1 - 3.6 7.5 11.2 4.6 7.1 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PI-PLC-X PF00388.19 OWF50138.1 - 3.6e-58 195.3 0.0 8.7e-58 194.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 OWF50138.1 - 4.7e-46 154.8 1.9 2.2e-22 78.9 0.1 2.6 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.19 OWF50138.1 - 4.4e-36 123.7 0.1 1.4e-35 122.1 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 PF00018.28 OWF50138.1 - 5.2e-16 58.0 0.4 1.4e-15 56.6 0.4 1.8 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 OWF50138.1 - 2e-13 50.7 0.2 1.1e-05 25.9 0.0 4.1 4 0 0 4 4 4 3 PH domain C2 PF00168.30 OWF50138.1 - 2.5e-12 47.0 0.0 7.2e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.6 OWF50138.1 - 1.6e-09 37.5 0.5 4.5e-09 36.0 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OWF50138.1 - 6e-05 22.6 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_12 PF16457.5 OWF50138.1 - 0.0049 17.4 0.0 0.16 12.5 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain DASH_Dad3 PF08656.10 OWF50138.1 - 0.29 11.2 1.5 8.3 6.6 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF2807 PF10988.8 OWF50139.1 - 0.39 10.5 3.3 7.2 6.4 3.3 2.0 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain SpoVS PF04232.12 OWF50139.1 - 3.2 7.5 5.0 40 4.0 0.4 3.5 1 1 4 5 5 5 0 Stage V sporulation protein S (SpoVS) Carb_anhydrase PF00194.21 OWF50140.1 - 3.5e-47 161.1 0.0 4.1e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ets PF00178.22 OWF50142.1 - 3.9e-35 120.2 0.2 9.7e-35 118.9 0.2 1.7 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 OWF50142.1 - 3.7e-15 55.7 1.1 7.7e-15 54.6 1.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain C1q PF00386.21 OWF50143.1 - 3.4e-16 59.6 0.1 5.7e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 C1q domain PKcGMP_CC PF16808.5 OWF50143.1 - 0.0023 17.8 1.7 0.0023 17.8 1.7 2.3 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 OWF50143.1 - 0.0072 16.9 2.1 0.008 16.8 0.5 1.9 1 1 1 2 2 2 1 SlyX Spc29 PF17082.5 OWF50143.1 - 0.014 15.2 0.9 0.024 14.5 0.9 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 NOPS PF08075.11 OWF50143.1 - 0.015 15.4 0.2 0.97 9.7 0.0 2.6 2 0 0 2 2 2 0 NOPS (NUC059) domain XhlA PF10779.9 OWF50143.1 - 0.022 15.0 2.4 0.045 14.0 2.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA CCDC53 PF10152.9 OWF50143.1 - 0.034 14.6 1.9 0.062 13.7 1.9 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex BclA_C PF18573.1 OWF50143.1 - 0.042 13.8 1.4 0.07 13.0 1.4 1.3 1 0 0 1 1 1 0 BclA C-terminal domain TMF_DNA_bd PF12329.8 OWF50143.1 - 0.078 13.0 5.5 0.48 10.4 3.5 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 OWF50143.1 - 0.18 9.7 2.0 0.22 9.4 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 OWF50143.1 - 0.34 11.4 3.1 0.85 10.1 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 C1q PF00386.21 OWF50144.1 - 3.9e-15 56.2 0.1 7.6e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 C1q domain SlyX PF04102.12 OWF50144.1 - 8e-05 23.2 9.4 0.0031 18.1 0.9 2.2 1 1 2 3 3 3 2 SlyX BclA_C PF18573.1 OWF50144.1 - 0.006 16.5 0.4 0.01 15.7 0.4 1.4 1 0 0 1 1 1 1 BclA C-terminal domain Spc29 PF17082.5 OWF50144.1 - 0.006 16.4 3.6 0.0091 15.9 3.6 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 BLOC1_2 PF10046.9 OWF50144.1 - 0.012 15.9 2.9 0.025 14.9 2.9 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 OWF50144.1 - 0.016 15.2 3.2 0.029 14.4 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.9 OWF50144.1 - 0.019 15.2 2.9 0.04 14.1 2.9 1.5 1 0 0 1 1 1 0 Haemolysin XhlA PKcGMP_CC PF16808.5 OWF50144.1 - 0.038 13.9 6.3 0.076 12.9 3.2 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Filo_VP35 PF02097.15 OWF50144.1 - 0.068 12.2 0.3 0.11 11.5 0.3 1.3 1 0 0 1 1 1 0 Filoviridae VP35 TMF_DNA_bd PF12329.8 OWF50144.1 - 0.075 13.0 8.4 0.076 13.0 5.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 OWF50144.1 - 0.11 13.0 4.5 0.15 12.5 4.5 1.2 1 0 0 1 1 1 0 Fez1 DUF3450 PF11932.8 OWF50144.1 - 0.13 11.6 4.0 0.19 11.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 OWF50144.1 - 0.13 12.4 8.7 0.15 12.3 6.9 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 OWF50144.1 - 0.14 12.2 4.4 0.27 11.3 4.3 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 OWF50144.1 - 0.16 12.1 2.4 0.41 10.8 2.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HSBP1 PF06825.12 OWF50144.1 - 0.19 11.6 2.4 1.1 9.2 1.9 2.5 1 1 0 1 1 1 0 Heat shock factor binding protein 1 DUF16 PF01519.16 OWF50144.1 - 0.44 11.1 6.5 0.27 11.7 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 CpxA_peri PF16527.5 OWF50144.1 - 0.64 10.4 3.7 14 6.0 0.9 2.4 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain UPF0242 PF06785.11 OWF50144.1 - 0.65 10.1 5.8 5.7 7.0 4.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 OWF50144.1 - 0.95 9.9 3.9 1.4 9.4 2.6 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 OWF50144.1 - 1.1 8.5 9.2 1.1 8.5 8.1 1.5 1 1 1 2 2 2 0 FAM76 protein DivIC PF04977.15 OWF50144.1 - 3.1 7.6 5.5 5.4 6.9 0.2 2.9 2 1 1 3 3 3 0 Septum formation initiator DUF948 PF06103.11 OWF50144.1 - 4.2 7.7 6.2 0.29 11.4 0.6 2.0 3 0 0 3 3 1 0 Bacterial protein of unknown function (DUF948) C1q PF00386.21 OWF50145.1 - 9.4e-12 45.2 0.0 9.7e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 OWF50145.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF50146.1 - 5.1e-14 52.6 0.1 1.2e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 C1q domain Sec20 PF03908.13 OWF50146.1 - 0.17 11.8 1.8 0.44 10.5 1.8 1.6 1 0 0 1 1 1 0 Sec20 SlyX PF04102.12 OWF50146.1 - 0.25 12.0 3.4 1.3 9.7 2.6 2.3 1 1 1 2 2 2 0 SlyX PKcGMP_CC PF16808.5 OWF50146.1 - 0.29 11.0 1.7 0.5 10.2 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF16 PF01519.16 OWF50146.1 - 3.7 8.1 7.4 0.48 10.9 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 OWF50146.1 - 4.9 7.2 6.3 1.2 9.2 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2981 PF11200.8 OWF50147.1 - 0.013 15.2 4.8 0.017 14.9 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Inhibitor_I53 PF11714.8 OWF50147.1 - 0.42 10.8 4.2 0.86 9.8 0.6 2.5 2 0 0 2 2 2 0 Thrombin inhibitor Madanin DUF5453 PF17534.2 OWF50147.1 - 0.43 10.5 3.8 2.8 7.9 3.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5453) Hid1 PF12722.7 OWF50147.1 - 0.91 7.6 11.2 1.1 7.2 11.2 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 OWF50147.1 - 6 6.8 13.1 12 5.9 13.1 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 OWF50147.1 - 6.7 5.4 16.8 8.4 5.1 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zip PF02535.22 OWF50147.1 - 6.9 5.8 11.5 1.3e+02 1.5 11.5 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter GSH_synth_ATP PF03917.17 OWF50150.1 - 1e-120 403.0 0.0 1.2e-120 402.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OWF50150.1 - 4.3e-29 101.0 0.1 1.3e-28 99.4 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Phi-29_GP16_7 PF06720.11 OWF50150.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 GSH_synth_ATP PF03917.17 OWF50151.1 - 3e-121 404.7 0.0 3.4e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OWF50151.1 - 1.6e-30 105.6 0.0 3.1e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Phi-29_GP16_7 PF06720.11 OWF50151.1 - 0.01 15.7 0.1 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 WAP PF00095.21 OWF50152.1 - 3.6e-07 30.5 11.0 4.9e-07 30.0 11.0 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Sfi1_C PF10638.9 OWF50153.1 - 0.33 11.7 3.3 2.5 8.9 0.6 2.1 1 1 1 2 2 2 0 Spindle body associated protein C-terminus zf-His_Me_endon PF05551.11 OWF50154.1 - 7.3e-06 26.2 7.1 8.8e-06 25.9 7.1 1.3 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease HNH_3 PF13392.6 OWF50154.1 - 0.023 14.5 1.4 0.044 13.5 1.4 1.7 1 1 0 1 1 1 0 HNH endonuclease Cytochrom_NNT PF03264.14 OWF50154.1 - 0.13 11.9 8.3 0.2 11.3 8.3 1.3 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region protein_MS5 PF04776.12 OWF50154.1 - 0.16 12.1 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein MS5 Cytochrome_C7 PF14522.6 OWF50154.1 - 0.16 12.0 7.7 0.22 11.5 7.7 1.3 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Claudin_2 PF13903.6 OWF50155.1 - 7.4e-06 25.8 11.0 7.7e-05 22.5 11.0 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 OWF50155.1 - 0.00021 21.6 3.1 0.00021 21.6 3.1 1.6 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 OWF50155.1 - 0.58 9.6 12.3 3.4 7.1 0.2 2.1 1 1 0 2 2 2 0 Clc-like Claudin_3 PF06653.11 OWF50155.1 - 1.4 8.8 15.7 2.9 7.8 15.7 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Retrotrans_gag PF03732.17 OWF50156.1 - 0.00038 20.7 0.0 0.071 13.4 0.0 2.3 1 1 1 2 2 2 2 Retrotransposon gag protein FtsK_alpha PF17854.1 OWF50157.1 - 0.0084 16.2 9.2 12 6.2 0.5 4.2 1 1 3 4 4 4 4 FtsK alpha domain SRCR PF00530.18 OWF50158.1 - 1e-16 61.2 0.1 3.3e-16 59.6 0.1 1.9 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Sushi PF00084.20 OWF50158.1 - 0.00014 22.4 4.5 0.00029 21.4 4.5 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) PAN_1 PF00024.26 OWF50158.1 - 0.0076 16.2 0.1 0.0076 16.2 0.1 2.0 2 0 0 2 2 2 1 PAN domain PARP PF00644.20 OWF50159.1 - 1.6e-67 226.9 0.0 3e-67 226.0 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OWF50159.1 - 4.1e-43 146.7 0.0 8.2e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OWF50159.1 - 1.5e-24 85.8 1.8 1.5e-24 85.8 1.8 2.5 3 0 0 3 3 3 1 WGR domain WWE PF02825.20 OWF50159.1 - 3.6e-24 85.1 8.5 9.6e-16 58.1 1.5 2.6 2 0 0 2 2 2 2 WWE domain Pkinase_Tyr PF07714.17 OWF50160.1 - 6.1e-84 281.3 0.0 1e-83 280.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 OWF50160.1 - 3.7e-51 174.3 0.4 6.1e-51 173.6 0.4 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.25 OWF50160.1 - 8.1e-44 150.0 0.0 5.1e-43 147.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Peripla_BP_6 PF13458.6 OWF50160.1 - 2.1e-15 57.2 0.0 5.4e-15 55.9 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 OWF50160.1 - 0.0094 15.0 0.2 0.02 13.9 0.2 1.5 1 0 0 1 1 1 1 Periplasmic binding protein domain OpuAC PF04069.12 OWF50160.1 - 0.015 14.9 0.0 0.77 9.3 0.0 2.4 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system Sedlin_N PF04628.13 OWF50160.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region MRAP PF15183.6 OWF50160.1 - 0.47 10.4 3.1 0.38 10.7 1.0 1.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family CobS_N PF12556.8 OWF50161.1 - 0.084 12.6 10.5 28 4.5 0.1 7.1 8 0 0 8 8 8 0 Cobaltochelatase CobS subunit N terminal MFS_1 PF07690.16 OWF50162.1 - 7.1e-31 107.4 23.1 8.3e-31 107.2 23.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2105 PF09878.9 OWF50162.1 - 0.0011 18.8 1.8 0.0011 18.8 1.8 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2105) OATP PF03137.20 OWF50162.1 - 0.0078 14.6 16.3 0.013 13.8 3.6 3.3 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OWF50162.1 - 0.27 10.1 30.0 0.078 11.8 2.2 3.1 1 1 2 3 3 3 0 Sugar (and other) transporter CPBP PF02517.16 OWF50162.1 - 0.34 11.3 4.5 0.25 11.7 0.1 2.5 2 2 0 2 2 2 0 CPBP intramembrane metalloprotease MFS_1 PF07690.16 OWF50163.1 - 7.8e-09 34.9 6.9 8.5e-09 34.8 6.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OWF50163.1 - 0.00019 19.9 9.5 0.00038 18.9 0.9 2.1 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_C48 PF02902.19 OWF50164.1 - 0.00022 21.2 0.5 0.011 15.6 0.0 2.0 1 1 1 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain PHD PF00628.29 OWF50164.1 - 0.082 12.8 11.4 0.17 11.8 11.4 1.6 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 OWF50165.1 - 5.8e-17 61.8 1.0 0.0003 21.5 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT_2 PF13646.6 OWF50165.1 - 0.088 13.2 0.0 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats Pkinase PF00069.25 OWF50166.1 - 6.4e-33 114.2 0.0 9.6e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF50166.1 - 1.3e-32 113.1 0.0 3.1e-32 111.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 OWF50166.1 - 6.1e-13 48.0 0.1 6.1e-13 48.0 0.1 1.8 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 OWF50166.1 - 0.00011 21.1 1.0 0.00016 20.6 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF4448 PF14610.6 OWF50166.1 - 0.0092 15.8 0.0 0.032 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) UPAR_LY6_2 PF16975.5 OWF50166.1 - 0.014 15.6 4.5 0.032 14.4 4.5 1.5 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 PspB PF06667.12 OWF50166.1 - 0.052 13.6 6.8 0.44 10.6 0.2 2.8 3 0 0 3 3 3 0 Phage shock protein B TMEM154 PF15102.6 OWF50166.1 - 0.078 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family FTA2 PF13095.6 OWF50166.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 BAMBI PF06211.12 OWF50166.1 - 0.41 10.9 3.5 0.94 9.8 3.5 1.5 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain TPR_12 PF13424.6 OWF50168.1 - 0.00029 21.1 0.3 0.37 11.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF50168.1 - 0.003 17.3 0.4 0.091 12.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF50168.1 - 0.02 15.0 0.1 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2 PF14299.6 OWF50168.1 - 0.038 14.0 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Phloem protein 2 TPR_7 PF13176.6 OWF50168.1 - 0.13 12.3 0.1 4.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 OWF50169.1 - 8.1e-44 148.1 15.1 6e-16 58.8 0.9 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OWF50169.1 - 2.3e-26 91.0 9.7 1.1e-06 28.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OWF50169.1 - 7.2e-25 87.0 5.5 3.3e-09 37.1 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50169.1 - 1.8e-23 80.0 6.5 0.00036 20.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OWF50169.1 - 8.8e-19 67.3 8.2 2.7e-06 27.5 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF50169.1 - 1.4e-05 25.3 0.9 2.9e-05 24.3 0.9 1.5 1 0 0 1 1 1 1 SOCS box M16C_assoc PF08367.11 OWF50170.1 - 4.3e-79 265.2 0.0 6.6e-79 264.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OWF50170.1 - 1.4e-26 93.6 0.1 4.9e-20 72.3 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OWF50170.1 - 6.9e-09 35.8 0.0 4.9e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) PP2C PF00481.21 OWF50171.1 - 2.7e-38 132.1 0.7 3.5e-30 105.5 0.0 3.8 2 1 0 3 3 3 3 Protein phosphatase 2C Paramyxo_ncap PF00973.19 OWF50171.1 - 9.8 5.0 10.5 1.2 8.0 3.7 2.0 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein EF-hand_7 PF13499.6 OWF50172.1 - 2.2e-10 40.8 0.1 1.1e-09 38.6 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF50172.1 - 5.4e-08 32.2 0.5 0.012 15.5 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF50172.1 - 4.4e-07 29.0 3.0 0.0046 16.4 0.1 2.9 3 0 0 3 3 3 2 EF hand DUF5580 PF17743.1 OWF50172.1 - 2.7e-05 22.9 0.0 4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_5 PF13202.6 OWF50172.1 - 5.9e-05 22.4 0.1 0.22 11.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF50172.1 - 0.0047 16.7 0.6 0.063 13.1 0.1 3.0 3 1 1 4 4 4 1 EF-hand domain pair Ras PF00071.22 OWF50173.1 - 1.8e-62 209.7 0.3 2.1e-62 209.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50173.1 - 2.6e-35 121.2 0.0 4.5e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50173.1 - 1.1e-12 47.7 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF50173.1 - 9.9e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF50173.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF50173.1 - 0.00043 20.2 0.2 0.32 10.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OWF50173.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MCR_beta PF02241.18 OWF50173.1 - 0.01 15.5 0.2 0.012 15.3 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain AAA_16 PF13191.6 OWF50173.1 - 0.02 15.3 0.1 0.033 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OWF50173.1 - 0.076 13.3 0.1 1.3 9.3 0.0 2.1 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 OWF50173.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 OWF50174.1 - 1.8e-53 180.5 0.1 2.2e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50174.1 - 2.2e-32 111.8 0.0 3.2e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50174.1 - 4.7e-13 49.0 0.0 6.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF50174.1 - 8e-05 22.6 0.8 0.1 12.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF50174.1 - 0.00036 20.6 0.0 0.00075 19.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF50174.1 - 0.00047 19.6 0.0 0.00068 19.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OWF50174.1 - 0.0034 17.2 0.1 0.0058 16.4 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 OWF50174.1 - 0.016 14.9 0.3 0.076 12.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF50174.1 - 0.029 14.9 0.3 0.047 14.2 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Hpr_kinase_C PF07475.12 OWF50174.1 - 0.056 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 OWF50174.1 - 0.067 13.6 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OWF50174.1 - 0.075 13.0 0.1 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 OWF50174.1 - 0.079 12.3 2.2 4 6.7 0.3 2.2 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 OWF50174.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 OWF50175.1 - 6.6e-57 191.6 0.3 8e-57 191.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50175.1 - 7.3e-32 110.1 0.1 1.9e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50175.1 - 3.2e-14 52.7 0.0 4.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF50175.1 - 7.3e-08 32.2 0.2 4.8e-07 29.5 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF50175.1 - 0.0013 18.7 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OWF50175.1 - 0.0013 18.2 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF50175.1 - 0.0081 16.2 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF50175.1 - 0.013 14.9 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OWF50175.1 - 0.015 15.1 0.1 0.044 13.5 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 OWF50175.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain 7tm_1 PF00001.21 OWF50176.1 - 8.8e-52 176.0 11.6 1.3e-51 175.4 11.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF50176.1 - 0.00027 20.8 12.6 0.00027 20.8 12.6 2.2 2 1 0 2 2 2 1 Olfactory receptor Pho88 PF10032.9 OWF50176.1 - 1.5 8.1 6.2 1.9 7.7 0.2 2.4 2 0 0 2 2 2 0 Phosphate transport (Pho88) DUF5620 PF18522.1 OWF50177.1 - 1.2e-10 41.9 9.7 15 6.0 0.1 9.3 1 1 9 10 10 10 7 Domain of unknown function (DUF5620) YceI PF04264.13 OWF50177.1 - 0.0057 17.2 0.0 7.3 7.1 0.0 4.2 1 1 0 1 1 1 1 YceI-like domain DUF4403 PF14356.6 OWF50177.1 - 0.019 13.7 0.0 7.2 5.2 0.0 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4403) Band_7 PF01145.25 OWF50178.1 - 7.6e-20 71.7 0.6 2.5e-19 70.0 0.1 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Shisa PF13908.6 OWF50179.1 - 0.00079 19.7 2.1 0.00079 19.7 2.1 3.0 3 1 0 3 3 3 2 Wnt and FGF inhibitory regulator DUF3836 PF12930.7 OWF50179.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Exo_endo_phos PF03372.23 OWF50180.1 - 2.1e-13 50.4 0.0 6.8e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Neur_chan_memb PF02932.16 OWF50181.1 - 4.6e-26 92.3 10.8 3.9e-21 76.2 8.7 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF50181.1 - 2.1e-23 82.9 0.1 3.7e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain C1q PF00386.21 OWF50182.1 - 1.7e-17 63.8 0.1 3.8e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF50182.1 - 0.00023 21.1 0.2 0.00023 21.1 0.2 1.8 2 0 0 2 2 2 1 BclA C-terminal domain FAM76 PF16046.5 OWF50182.1 - 0.014 14.7 2.2 0.026 13.9 2.2 1.4 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 OWF50182.1 - 0.023 15.3 3.6 0.055 14.1 3.6 1.7 1 0 0 1 1 1 0 SlyX DUF641 PF04859.12 OWF50182.1 - 0.025 14.9 0.6 0.045 14.1 0.6 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 OWF50182.1 - 0.035 14.6 4.3 0.063 13.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 XLF PF09302.11 OWF50182.1 - 0.059 13.5 5.8 0.32 11.1 1.1 2.3 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component AAA_13 PF13166.6 OWF50182.1 - 0.061 12.0 0.9 0.088 11.4 0.9 1.1 1 0 0 1 1 1 0 AAA domain Tup_N PF08581.10 OWF50182.1 - 0.071 13.4 2.7 0.13 12.5 2.7 1.4 1 0 0 1 1 1 0 Tup N-terminal Spc29 PF17082.5 OWF50182.1 - 0.082 12.7 2.5 0.14 11.9 2.5 1.4 1 1 0 1 1 1 0 Spindle Pole Component 29 Fib_alpha PF08702.10 OWF50182.1 - 0.086 13.0 2.4 0.15 12.3 2.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 OWF50182.1 - 0.17 11.9 3.0 0.36 10.9 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 OWF50182.1 - 0.19 11.7 4.1 0.34 10.9 4.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 OWF50182.1 - 1.6 8.6 4.4 3.6 7.4 2.2 2.4 2 1 1 3 3 3 0 Septum formation initiator Myb_DNA-bind_4 PF13837.6 OWF50183.1 - 4.6e-13 49.4 0.2 4.6e-13 49.4 0.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 OWF50183.1 - 0.0016 18.7 0.7 0.0016 18.7 0.7 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 OWF50183.1 - 0.0019 19.1 0.5 0.0053 17.7 0.5 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF3334 PF11813.8 OWF50183.1 - 0.17 11.6 0.1 0.17 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Ank_2 PF12796.7 OWF50184.1 - 1.1e-22 80.4 0.0 1.3e-16 60.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF50184.1 - 1.8e-16 60.0 0.0 3.5e-06 27.2 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF50184.1 - 2.3e-16 59.9 0.0 5.5e-07 30.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50184.1 - 1.8e-11 43.2 0.0 0.063 13.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OWF50184.1 - 2.1e-11 43.7 0.0 0.00015 22.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat C1q PF00386.21 OWF50185.1 - 9.9e-23 80.7 0.4 1.6e-22 80.1 0.4 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF50185.1 - 0.00051 20.0 0.4 0.0009 19.1 0.4 1.4 1 0 0 1 1 1 1 BclA C-terminal domain BRI3BP PF14965.6 OWF50185.1 - 0.0021 17.6 0.2 0.0035 16.9 0.2 1.3 1 0 0 1 1 1 1 Negative regulator of p53/TP53 MYO10_CC PF16735.5 OWF50185.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain TolA_bind_tri PF16331.5 OWF50185.1 - 0.065 13.3 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation DivIC PF04977.15 OWF50185.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 OWF50185.1 - 0.14 12.6 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) C1q PF00386.21 OWF50186.1 - 7.2e-24 84.4 0.5 1e-23 84.0 0.5 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF50186.1 - 0.0011 18.9 0.4 0.0021 18.0 0.4 1.5 1 0 0 1 1 1 1 BclA C-terminal domain BRI3BP PF14965.6 OWF50186.1 - 0.0034 16.9 0.2 0.0049 16.4 0.2 1.3 1 0 0 1 1 1 1 Negative regulator of p53/TP53 TNF PF00229.18 OWF50186.1 - 0.055 13.4 0.2 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family DivIC PF04977.15 OWF50186.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator TPR_MLP1_2 PF07926.12 OWF50186.1 - 0.21 11.7 0.1 0.43 10.6 0.1 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 OWF50186.1 - 0.22 12.2 0.3 0.64 10.7 0.2 1.7 2 0 0 2 2 2 0 SlyX Complex1_49kDa PF00346.19 OWF50187.1 - 8.1e-129 428.5 0.0 1.2e-128 427.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 OWF50187.1 - 0.0095 14.9 0.0 0.018 14.0 0.0 1.5 1 1 0 1 1 1 1 Nickel-dependent hydrogenase TIG PF01833.24 OWF50188.1 - 1.8e-146 476.6 156.6 2.1e-14 53.4 2.9 16.1 15 0 0 15 15 15 14 IPT/TIG domain G8 PF10162.9 OWF50188.1 - 1.7e-63 212.2 2.7 1.8e-35 121.7 0.5 3.2 2 0 0 2 2 2 2 G8 domain PA14 PF07691.12 OWF50188.1 - 1.8e-05 24.6 1.9 4.9e-05 23.2 1.0 2.3 2 0 0 2 2 2 1 PA14 domain Cadherin_C_2 PF16492.5 OWF50188.1 - 0.0015 19.2 2.0 0.0046 17.7 0.0 2.7 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal GLEYA PF10528.9 OWF50188.1 - 0.013 15.9 0.2 0.086 13.3 0.2 2.6 1 0 0 1 1 1 0 GLEYA domain TMEM154 PF15102.6 OWF50188.1 - 0.074 13.0 0.1 0.34 10.8 0.1 2.2 1 0 0 1 1 1 0 TMEM154 protein family RVT_1 PF00078.27 OWF50189.1 - 2.6e-17 63.1 4.8 1.6e-14 53.9 0.8 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4 PF00097.25 OWF50190.1 - 0.00021 21.1 5.0 0.00021 21.1 5.0 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF50190.1 - 0.00056 19.7 5.6 0.00056 19.7 5.6 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF50190.1 - 0.0013 18.7 4.4 0.0013 18.7 4.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF50190.1 - 0.0043 17.4 6.3 0.0043 17.4 6.3 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF50190.1 - 0.013 15.6 5.3 0.013 15.6 5.3 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING BOF PF04076.13 OWF50190.1 - 0.017 15.2 0.1 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial OB fold (BOF) protein zf-C3HC4_2 PF13923.6 OWF50190.1 - 0.019 14.8 6.4 0.019 14.8 6.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 OWF50190.1 - 0.054 13.3 0.7 0.16 11.9 0.4 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 OWF50190.1 - 5.2 7.2 15.2 0.12 12.5 7.1 2.5 2 1 0 2 2 2 0 RING-type zinc-finger NUDIX PF00293.28 OWF50191.1 - 1.9e-17 63.5 0.0 3.7e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain NUDIX_2 PF13869.6 OWF50191.1 - 0.00018 21.2 0.0 0.0023 17.6 0.0 2.3 2 1 0 2 2 2 1 Nucleotide hydrolase Pro_isomerase PF00160.21 OWF50192.1 - 7.1e-39 133.6 0.0 7.1e-39 133.6 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OWF50192.1 - 1e-16 60.5 0.1 2.3e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF50192.1 - 0.063 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAP1C PF05609.12 OWF50192.1 - 4.7 6.2 16.2 78 2.2 16.5 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 OWF50192.1 - 5.1 6.8 16.6 10 5.9 16.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.27 OWF50193.1 - 6.9e-61 202.2 0.2 3.6e-19 68.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF50193.1 - 0.16 11.1 0.2 8.2 5.5 0.0 2.6 1 1 2 3 3 3 0 Gammaproteobacterial serine protease NAD_synthase PF02540.17 OWF50194.1 - 3.1e-28 98.5 0.0 6e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 OWF50194.1 - 5.5e-17 62.0 0.0 1.2e-16 60.8 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.21 OWF50194.1 - 0.044 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase DUF1125 PF06563.11 OWF50195.1 - 0.003 17.4 83.2 1.2 9.1 0.6 16.2 3 3 12 15 15 15 9 Protein of unknown function (DUF1125) UPAR_LY6_2 PF16975.5 OWF50195.1 - 0.64 10.2 42.5 5.8 7.2 1.2 7.7 1 1 4 6 6 6 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Catalase PF00199.19 OWF50196.1 - 3.9e-196 651.7 0.3 4.7e-196 651.4 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OWF50196.1 - 2e-21 76.0 0.1 9.3e-21 73.8 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF4128 PF13554.6 OWF50196.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Catalase PF00199.19 OWF50197.1 - 6.8e-194 644.3 0.2 8.5e-194 644.0 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OWF50197.1 - 2.2e-20 72.6 0.1 1e-19 70.5 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive ADH_N PF08240.12 OWF50198.1 - 1.2e-26 92.7 0.6 1.2e-26 92.7 0.6 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OWF50198.1 - 7.6e-25 87.4 0.2 1e-23 83.7 0.0 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OWF50198.1 - 2.5e-05 23.7 0.1 3.9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 OWF50198.1 - 5.1e-05 22.8 0.1 0.00026 20.6 0.1 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OWF50198.1 - 0.0098 17.0 0.0 0.02 15.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MTS PF05175.14 OWF50198.1 - 0.16 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Mt_ATP-synt_B PF05405.14 OWF50199.1 - 4.2e-17 62.2 0.1 5.7e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PsbM PF05151.12 OWF50199.1 - 0.32 10.8 1.2 2.1 8.2 0.6 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) PID PF00640.23 OWF50200.1 - 6.7e-22 78.0 0.1 1.7e-21 76.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 OWF50200.1 - 8.2e-11 41.6 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF50200.1 - 8.5e-09 34.9 0.0 1.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PID_2 PF14719.6 OWF50200.1 - 0.00039 20.3 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 OWF50200.1 - 0.00087 18.9 0.0 0.0049 16.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Tmemb_9 PF05434.11 OWF50201.1 - 3.6e-45 153.4 7.9 3.6e-45 153.4 7.9 1.8 1 1 1 2 2 2 1 TMEM9 Gemini_mov PF01708.16 OWF50201.1 - 0.0039 16.9 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Geminivirus putative movement protein V_ATPase_I PF01496.19 OWF50201.1 - 0.057 11.3 0.2 0.073 11.0 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T2SSM PF04612.12 OWF50201.1 - 0.073 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Pex24p PF06398.11 OWF50201.1 - 0.075 12.0 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF5531 PF17671.1 OWF50201.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5531) TRP PF06011.12 OWF50201.1 - 0.11 11.2 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF4834 PF16118.5 OWF50201.1 - 0.12 13.3 0.1 0.25 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4061 PF13270.6 OWF50202.1 - 1e-33 115.5 6.0 1.4e-33 115.1 6.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) MRPL52 PF18699.1 OWF50202.1 - 0.04 14.1 0.1 0.081 13.1 0.1 1.6 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Shikimate_DH PF01488.20 OWF50203.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 OWF50204.1 - 3.7e-19 70.1 0.0 6.5e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OWF50204.1 - 2.5e-11 43.7 0.0 4.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF50204.1 - 2.6e-09 36.9 0.8 1.2e-08 34.8 0.0 2.2 2 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 OWF50204.1 - 0.0061 16.3 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 OWF50204.1 - 0.066 12.7 0.2 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 OWF50204.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Neur_chan_LBD PF02931.23 OWF50205.1 - 3.3e-43 147.6 0.4 4.4e-43 147.2 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50205.1 - 5.6e-11 43.0 16.9 7.1e-11 42.6 7.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ank_2 PF12796.7 OWF50207.1 - 7.7e-17 61.7 0.9 3.4e-05 24.3 0.0 4.9 3 2 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50207.1 - 5.3e-10 39.6 0.4 0.0018 18.8 0.0 6.1 6 1 1 7 7 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF50207.1 - 5.8e-09 36.0 3.1 0.078 13.3 0.0 6.4 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50207.1 - 6.1e-07 29.3 3.2 0.62 10.8 0.0 7.1 7 1 1 8 8 6 1 Ankyrin repeat DUF2075 PF09848.9 OWF50207.1 - 0.004 16.5 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OWF50207.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ank PF00023.30 OWF50207.1 - 0.024 15.1 0.1 93 3.7 0.0 4.3 3 0 0 3 3 3 0 Ankyrin repeat NACHT PF05729.12 OWF50207.1 - 0.041 13.8 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Ploopntkinase2 PF18747.1 OWF50207.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 Hormone_4 PF00220.17 OWF50207.1 - 0.13 12.3 1.5 0.59 10.2 1.5 2.1 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain ResIII PF04851.15 OWF50207.1 - 0.14 12.1 4.9 0.2 11.6 3.5 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SYF2 PF08231.12 OWF50207.1 - 0.14 12.5 3.6 0.083 13.3 0.9 1.9 2 0 0 2 2 2 0 SYF2 splicing factor AAA_7 PF12775.7 OWF50207.1 - 0.2 11.1 1.3 2.4 7.6 0.0 2.8 2 1 1 3 3 3 0 P-loop containing dynein motor region Ank_2 PF12796.7 OWF50208.1 - 1e-09 38.8 0.1 5.9e-06 26.8 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF50208.1 - 1.5e-06 28.3 0.1 0.015 15.6 0.1 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF50208.1 - 7e-06 26.5 0.0 0.00067 20.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50208.1 - 0.00012 22.2 0.0 4 8.3 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat ResIII PF04851.15 OWF50208.1 - 0.0068 16.4 0.8 0.0068 16.4 0.8 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF50208.1 - 0.0092 16.3 0.0 0.055 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OWF50208.1 - 0.028 14.4 0.3 0.11 12.5 0.3 2.1 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 OWF50208.1 - 0.028 13.7 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OWF50208.1 - 0.04 13.4 0.0 0.096 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Ank PF00023.30 OWF50208.1 - 0.088 13.3 0.0 11 6.7 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat APS_kinase PF01583.20 OWF50208.1 - 0.13 12.2 0.2 18 5.2 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase 5_nucleotid_C PF02872.18 OWF50209.1 - 1.3e-45 155.5 0.0 2.1e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OWF50209.1 - 6.4e-14 52.9 0.2 1.2e-13 52.0 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 OWF50209.1 - 0.001 18.6 1.0 0.014 14.8 1.0 2.4 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap CDKN3 PF05706.12 OWF50209.1 - 0.12 12.0 0.1 8.4 6.0 0.1 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) APG17 PF04108.12 OWF50209.1 - 0.21 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Phosducin PF02114.16 OWF50210.1 - 5.1e-20 71.5 0.1 1.5e-19 69.9 0.1 1.5 1 1 1 2 2 2 1 Phosducin DUF3886 PF13025.6 OWF50210.1 - 0.0019 18.3 2.3 0.0039 17.3 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3886) iPGM_N PF06415.13 OWF50210.1 - 0.12 11.8 1.3 0.18 11.3 1.3 1.2 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) DUF572 PF04502.13 OWF50210.1 - 0.24 11.0 3.2 0.32 10.6 3.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PIH1 PF08190.12 OWF50211.1 - 5.8e-38 130.0 0.0 8.6e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 OWF50211.1 - 1.2e-13 51.3 0.0 2.7e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain CMS1 PF14617.6 OWF50212.1 - 4.4e-21 75.4 7.0 6.9e-21 74.7 7.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OWF50212.1 - 0.0068 16.2 0.2 0.0084 15.9 0.2 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.14 OWF50212.1 - 5.1 5.3 11.1 6.6 4.9 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.6 OWF50212.1 - 7.3 6.1 10.5 2.3 7.8 0.0 2.6 2 1 0 2 2 2 0 Putative metallopeptidase domain TRAPPC10 PF12584.8 OWF50213.1 - 2.2e-13 50.2 0.5 8e-13 48.4 0.5 2.0 1 1 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 OWF50213.1 - 4.7e-05 23.1 0.1 0.00011 21.9 0.1 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 SNAP PF14938.6 OWF50213.1 - 0.034 13.6 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 OWF50213.1 - 0.088 13.3 0.5 0.23 12.0 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF50213.1 - 0.21 11.9 2.1 0.75 10.1 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Phos_pyr_kin PF08543.12 OWF50214.1 - 3.3e-23 82.4 0.0 4e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OWF50214.1 - 2.2e-14 53.4 0.0 4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase adh_short_C2 PF13561.6 OWF50215.1 - 3.4e-61 206.8 0.0 4e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF50215.1 - 1.1e-44 152.2 0.0 1.4e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OWF50215.1 - 3e-05 23.6 0.0 8.3e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OWF50215.1 - 4.8e-05 23.4 0.1 0.00012 22.1 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OWF50215.1 - 0.0012 18.8 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 OWF50215.1 - 0.03 14.3 0.2 0.058 13.4 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OWF50215.1 - 0.072 12.7 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OWF50215.1 - 0.099 12.9 0.1 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MGC-24 PF05283.11 OWF50216.1 - 1.2e-06 29.0 3.0 1.2e-06 29.0 3.0 2.5 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 OWF50216.1 - 1.8e-06 27.9 1.3 1.8e-06 27.9 1.3 2.6 2 2 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 OWF50216.1 - 0.00019 22.2 0.0 0.00049 20.9 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 OWF50216.1 - 0.00024 21.2 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5305 PF17231.2 OWF50216.1 - 0.0017 17.8 3.6 0.004 16.6 3.6 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Stevor PF17410.2 OWF50216.1 - 0.0045 16.6 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Herpes_gE PF02480.16 OWF50216.1 - 0.005 15.7 0.0 0.008 15.0 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 OWF50216.1 - 0.0075 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Amnionless Adeno_E3_CR2 PF02439.15 OWF50216.1 - 0.011 15.5 0.2 0.02 14.6 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 OWF50216.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YajC PF02699.15 OWF50216.1 - 0.015 15.1 0.2 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Neur_chan_memb PF02932.16 OWF50216.1 - 0.023 14.8 0.6 0.048 13.7 0.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SIT PF15330.6 OWF50216.1 - 0.1 13.1 0.4 0.38 11.2 0.0 2.1 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Syndecan PF01034.20 OWF50216.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain FixQ PF05545.11 OWF50216.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ ABC2_membrane_3 PF12698.7 OWF50216.1 - 0.36 9.9 2.4 0.27 10.3 0.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein FeoB_associated PF12669.7 OWF50216.1 - 1.1 9.7 4.4 2.3 8.7 4.4 1.5 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CCDC144C PF14915.6 OWF50218.1 - 0.0031 16.7 2.5 0.0048 16.1 2.5 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF1664 PF07889.12 OWF50218.1 - 0.015 15.3 0.7 0.028 14.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DSBA PF01323.20 OWF50218.1 - 0.048 13.4 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Angiomotin_C PF12240.8 OWF50218.1 - 0.076 12.6 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Angiomotin C terminal ADK PF00406.22 OWF50219.1 - 1.6e-53 180.8 11.2 1.4e-20 73.9 0.0 6.5 6 0 0 6 6 6 4 Adenylate kinase AAA_17 PF13207.6 OWF50219.1 - 4.7e-26 91.8 50.8 7.8e-11 42.6 0.0 9.3 7 2 2 10 10 6 5 AAA domain FAP206 PF12018.8 OWF50219.1 - 1.5e-24 86.9 2.4 2.8e-08 33.6 0.1 5.9 6 0 0 6 6 5 3 Domain of unknown function AAA_33 PF13671.6 OWF50219.1 - 9.2e-16 58.3 13.2 0.001 19.2 0.0 6.6 5 1 1 6 6 5 3 AAA domain AAA PF00004.29 OWF50219.1 - 4.2e-13 49.9 4.5 0.012 16.0 0.0 5.1 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF50219.1 - 6.9e-12 45.8 0.9 0.0061 16.8 0.0 5.0 5 0 0 5 5 4 3 AAA domain AAA_24 PF13479.6 OWF50219.1 - 4.9e-07 29.7 3.0 0.097 12.4 0.0 4.4 5 0 0 5 5 4 2 AAA domain RNA_helicase PF00910.22 OWF50219.1 - 5.4e-07 30.0 1.0 0.38 11.2 0.0 5.0 5 0 0 5 5 4 1 RNA helicase Hydin_ADK PF17213.3 OWF50219.1 - 5.5e-07 30.1 2.8 1.2e-06 28.9 2.1 6.8 7 2 1 8 8 3 2 Hydin Adenylate kinase-like domain YHS PF04945.13 OWF50219.1 - 3.8e-06 26.9 2.0 0.059 13.5 0.0 4.4 5 0 0 5 5 4 2 YHS domain NACHT PF05729.12 OWF50219.1 - 4e-06 26.8 0.1 0.0024 17.8 0.0 3.8 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.27 OWF50219.1 - 6e-06 26.8 4.6 0.15 12.6 0.1 5.3 5 0 0 5 5 4 1 ABC transporter AAA_5 PF07728.14 OWF50219.1 - 8.4e-06 25.8 1.2 0.29 11.1 0.0 4.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OWF50219.1 - 5.9e-05 22.5 0.4 0.37 10.1 0.0 4.1 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 OWF50219.1 - 7.4e-05 22.2 0.0 0.18 11.2 0.0 3.6 3 0 0 3 3 3 1 Bacterial TniB protein AAA_14 PF13173.6 OWF50219.1 - 0.00015 21.8 2.2 5.4 7.1 0.1 5.1 5 0 0 5 5 4 1 AAA domain Roc PF08477.13 OWF50219.1 - 0.00021 21.5 0.0 2 8.7 0.0 3.9 4 0 0 4 4 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 OWF50219.1 - 0.00022 21.5 25.8 0.005 17.1 0.0 6.3 6 1 0 6 6 5 3 AAA domain SKI PF01202.22 OWF50219.1 - 0.00023 21.3 0.0 0.00023 21.3 0.0 6.0 6 1 1 7 7 4 2 Shikimate kinase RuvB_N PF05496.12 OWF50219.1 - 0.00026 20.8 0.1 2.4 7.9 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OWF50219.1 - 0.00047 20.6 19.5 0.1 13.0 0.0 6.4 7 0 0 7 7 6 2 AAA ATPase domain KTI12 PF08433.10 OWF50219.1 - 0.0028 17.2 0.2 7.4 5.9 0.0 3.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 OWF50219.1 - 0.0036 17.4 1.1 23 5.1 0.0 4.2 4 0 0 4 4 3 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OWF50219.1 - 0.0036 17.8 0.1 0.12 12.9 0.0 7.3 6 2 1 7 7 5 4 AAA domain IstB_IS21 PF01695.17 OWF50219.1 - 0.0036 17.0 0.0 2.1 8.1 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 OWF50219.1 - 0.0066 16.0 0.0 8.5 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 OWF50219.1 - 0.023 14.6 0.2 8.1 6.3 0.0 3.8 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 OWF50219.1 - 0.051 13.6 0.0 6.3 6.8 0.0 3.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OWF50219.1 - 0.06 13.1 0.1 80 3.1 0.0 3.6 4 0 0 4 4 3 0 P-loop containing region of AAA domain AAA_19 PF13245.6 OWF50219.1 - 0.16 12.3 0.4 6.5 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 OWF50219.1 - 0.17 11.4 2.3 1.8 7.9 0.0 3.4 4 0 0 4 4 3 0 PhoH-like protein Cytidylate_kin PF02224.18 OWF50219.1 - 0.18 11.5 16.1 0.76 9.5 0.0 5.4 6 0 0 6 6 4 0 Cytidylate kinase SRPRB PF09439.10 OWF50219.1 - 1.4 8.3 11.9 20 4.6 0.0 4.6 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit Phosphodiest PF01663.22 OWF50220.1 - 3.3e-64 217.7 1.5 4.2e-64 217.4 1.5 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF50220.1 - 0.00018 21.1 0.1 0.0035 16.8 0.0 2.2 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.17 OWF50220.1 - 0.031 12.9 0.5 2.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Utp14 PF04615.13 OWF50221.1 - 1.4e-161 539.8 66.2 1.4e-161 539.8 66.2 2.1 1 1 1 2 2 2 1 Utp14 protein TTL PF03133.15 OWF50223.1 - 2.4e-79 266.5 0.1 5.7e-79 265.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF50223.1 - 1.3e-05 24.6 0.0 0.0011 18.2 0.0 3.1 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF50223.1 - 0.0043 16.3 0.0 0.085 12.1 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Acyl-CoA_ox_N PF14749.6 OWF50223.1 - 0.0055 17.3 0.3 0.014 16.0 0.3 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF5137 PF17220.3 OWF50224.1 - 0.026 15.4 32.2 1.6 9.6 4.0 5.0 1 1 2 3 3 3 0 Protein of unknown function (DUF5137) Torsin PF06309.11 OWF50224.1 - 0.53 10.4 10.2 4 7.6 0.5 3.1 1 1 2 3 3 3 0 Torsin FAO_M PF16350.5 OWF50224.1 - 1.3 9.5 9.7 0.99 9.8 0.7 3.9 1 1 3 4 4 4 0 FAD dependent oxidoreductase central domain SEP PF08059.13 OWF50225.1 - 9.5e-17 61.3 0.0 2.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OWF50225.1 - 7.5e-06 26.1 0.0 5.3e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 UBX domain TMPIT PF07851.13 OWF50225.1 - 0.0029 16.9 0.9 0.0047 16.2 0.9 1.2 1 0 0 1 1 1 1 TMPIT-like protein FAM76 PF16046.5 OWF50225.1 - 0.0039 16.6 0.1 0.0064 15.9 0.1 1.3 1 0 0 1 1 1 1 FAM76 protein sCache_like PF16736.5 OWF50225.1 - 0.1 12.7 1.8 0.22 11.6 1.8 1.5 1 0 0 1 1 1 0 Single Cache-like Nup54 PF13874.6 OWF50225.1 - 0.13 12.3 2.3 0.24 11.5 2.3 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF16 PF01519.16 OWF50225.1 - 0.14 12.7 2.7 0.22 12.0 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 OWF50225.1 - 1.1 9.9 3.3 1.8 9.2 2.0 2.0 1 1 1 2 2 2 0 SlyX Sec23_trunk PF04811.15 OWF50226.1 - 1.8e-08 34.3 0.2 3.9e-07 29.9 0.2 2.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain VWA_2 PF13519.6 OWF50226.1 - 2.7e-07 31.2 1.1 0.00068 20.2 0.5 3.9 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-Sec23_Sec24 PF04810.15 OWF50226.1 - 3.9e-06 26.8 0.2 9.5e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OWF50226.1 - 0.0098 16.6 0.1 0.1 13.4 0.1 2.7 2 1 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain VWA_CoxE PF05762.14 OWF50226.1 - 0.035 13.5 0.5 6.5 6.1 0.1 2.4 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein eRF1_2 PF03464.15 OWF50226.1 - 0.51 10.7 2.1 1.3 9.4 0.0 2.7 4 0 0 4 4 4 0 eRF1 domain 2 Big_3_4 PF13754.6 OWF50227.1 - 0.025 14.3 10.1 4.9 7.0 0.1 4.5 1 1 3 5 5 5 0 Domain of unknown function DUF4979 PF16351.5 OWF50227.1 - 0.048 13.9 7.8 1.6 9.0 0.6 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4979) Limkain-b1 PF11608.8 OWF50227.1 - 4.2 7.5 12.9 90 3.3 0.1 6.4 3 2 4 8 8 8 0 Limkain b1 Ank_2 PF12796.7 OWF50228.1 - 3e-17 63.0 0.5 4.8e-10 39.9 0.1 3.9 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50228.1 - 4e-10 40.0 0.2 0.0034 17.9 0.0 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50228.1 - 8.5e-10 38.0 0.5 0.13 12.9 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OWF50228.1 - 7.7e-08 32.5 1.2 0.00052 20.2 0.1 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DED PF01335.21 OWF50228.1 - 1.1e-06 28.9 0.2 4.4e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 Death effector domain Ank PF00023.30 OWF50228.1 - 1.1e-05 25.6 1.8 1.3 9.6 0.0 4.8 6 0 0 6 6 4 2 Ankyrin repeat AAA_22 PF13401.6 OWF50228.1 - 0.0049 17.2 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OWF50228.1 - 0.014 15.3 0.0 0.097 12.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.15 OWF50228.1 - 0.016 15.2 0.6 0.041 13.9 0.6 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OWF50228.1 - 0.02 14.4 0.3 0.17 11.3 0.0 2.2 1 1 1 2 2 2 0 PhoH-like protein ATP-grasp_6 PF18419.1 OWF50228.1 - 0.05 13.2 0.7 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 ATP-grasp-like domain DUF2075 PF09848.9 OWF50228.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L44 PF00935.19 OWF50229.1 - 2e-35 121.1 13.0 3.3e-35 120.4 13.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 LRV_FeS PF05484.11 OWF50229.1 - 3.2 7.8 6.0 0.84 9.7 0.6 2.0 2 0 0 2 2 2 0 LRV protein FeS4 cluster Thiolase_N PF00108.23 OWF50230.1 - 8.4e-102 340.0 4.8 8.4e-102 340.0 4.8 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OWF50230.1 - 6.6e-50 167.9 2.8 8.5e-50 167.5 0.4 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OWF50230.1 - 0.00091 18.9 1.6 0.00091 18.9 1.6 2.9 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 OWF50230.1 - 0.00095 19.3 0.1 0.01 16.0 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 OWF50230.1 - 0.0038 17.0 1.8 0.19 11.6 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Adeno_E3_CR2 PF02439.15 OWF50232.1 - 1e-05 25.2 0.1 2.3e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 OWF50232.1 - 0.00078 19.5 0.3 0.0013 18.7 0.3 1.3 1 0 0 1 1 1 1 Protocadherin MAP17 PF15807.5 OWF50232.1 - 0.031 14.5 0.3 0.056 13.7 0.3 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 OWF50232.1 - 0.039 14.8 0.3 0.12 13.2 0.3 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S49_N PF08496.10 OWF50232.1 - 0.09 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMEM154 PF15102.6 OWF50232.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family LSM PF01423.22 OWF50233.1 - 1.2e-17 63.4 0.5 1.4e-17 63.1 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OWF50233.1 - 0.0064 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Hfq protein EF-hand_7 PF13499.6 OWF50234.1 - 1e-08 35.5 1.0 0.00044 20.6 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF50234.1 - 0.00011 21.8 1.2 0.019 14.8 0.0 4.1 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 OWF50234.1 - 0.00059 19.2 1.7 0.013 15.0 0.0 3.9 5 0 0 5 5 5 1 EF hand DUF1126 PF06565.12 OWF50234.1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 DUF1126 PH-like domain EF-hand_10 PF14788.6 OWF50234.1 - 0.012 15.5 0.1 0.2 11.6 0.0 2.9 3 0 0 3 3 3 0 EF hand BORG_CEP PF14957.6 OWF50234.1 - 2 9.6 0.0 2 9.6 0.0 3.5 3 1 0 3 3 3 0 Cdc42 effector Ost5 PF05251.12 OWF50236.1 - 4.4e-28 97.4 6.1 4.4e-28 97.4 6.1 2.3 2 1 0 2 2 2 1 Oligosaccharyltransferase subunit 5 Phage_holin_3_3 PF16083.5 OWF50236.1 - 0.0047 17.0 1.2 0.0086 16.2 0.9 1.6 1 1 0 1 1 1 1 LydA holin phage, holin superfamily III SSPI PF14098.6 OWF50236.1 - 0.09 12.9 3.8 1.8 8.8 0.0 2.3 1 1 0 2 2 2 0 Small, acid-soluble spore protein I DUF4059 PF13268.6 OWF50236.1 - 1.7 9.1 7.2 0.12 12.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) C2 PF00168.30 OWF50237.1 - 1e-31 109.3 0.4 1.6e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 OWF50237.1 - 0.059 13.2 0.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 C2 domain in Dock180 and Zizimin proteins PROL5-SMR PF15621.6 OWF50237.1 - 0.085 13.4 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family C2 PF00168.30 OWF50238.1 - 3.9e-39 133.1 0.3 3.3e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 OWF50238.1 - 0.00049 20.0 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.6 OWF50238.1 - 0.0038 17.1 0.5 1.1 9.1 0.2 2.4 1 1 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins Protocadherin PF08374.11 OWF50238.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Voltage_CLC PF00654.20 OWF50238.1 - 0.052 12.8 0.2 0.072 12.3 0.2 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel UPAR_LY6 PF00021.21 OWF50239.1 - 9.1e-05 23.1 11.4 9.1e-05 23.1 11.4 5.0 5 0 0 5 5 5 2 u-PAR/Ly-6 domain ShK PF01549.24 OWF50239.1 - 0.0033 17.9 5.6 0.0033 17.9 5.6 5.9 4 1 0 5 5 5 2 ShK domain-like Ank_2 PF12796.7 OWF50240.1 - 6.1e-13 49.2 0.1 0.00088 19.8 0.0 5.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF50240.1 - 0.00014 22.0 0.0 68 4.5 0.0 6.3 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 OWF50240.1 - 0.00016 21.9 0.0 16 6.0 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 OWF50240.1 - 0.006 16.9 0.0 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OWF50240.1 - 0.011 15.7 1.6 0.011 15.7 1.6 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OWF50240.1 - 0.032 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 OWF50240.1 - 0.045 13.0 0.0 0.098 11.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 OWF50240.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 OWF50240.1 - 0.17 11.6 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain rve PF00665.26 OWF50242.1 - 0.015 15.5 0.0 0.018 15.2 0.0 1.2 1 1 0 1 1 1 0 Integrase core domain HECT PF00632.25 OWF50243.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Ras PF00071.22 OWF50244.1 - 1.7e-49 167.5 0.0 2.1e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50244.1 - 3.9e-18 65.8 0.1 1e-17 64.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50244.1 - 2.6e-07 30.2 0.0 3.8e-07 29.7 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF50244.1 - 1.5e-06 28.2 0.4 0.019 14.8 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 OWF50244.1 - 8.9e-05 21.6 0.1 0.13 11.2 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OWF50244.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF50244.1 - 0.0022 17.6 0.0 0.0067 16.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OWF50244.1 - 0.011 15.3 0.1 0.055 13.0 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 OWF50244.1 - 0.014 15.8 0.1 0.029 14.7 0.1 1.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 OWF50244.1 - 0.015 15.0 0.8 0.37 10.5 0.0 2.7 1 1 1 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 OWF50244.1 - 0.069 13.2 0.0 0.24 11.4 0.0 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 OWF50244.1 - 0.085 13.1 0.5 1 9.6 0.0 2.4 1 1 2 3 3 3 0 AAA domain AAA_28 PF13521.6 OWF50244.1 - 0.086 13.1 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RdRP PF05183.12 OWF50245.1 - 1.5e-145 486.2 0.1 1.6e-145 486.0 0.1 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase Myosin_head PF00063.21 OWF50247.1 - 1.6e-185 618.2 0.8 2.7e-185 617.5 0.8 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Chitin_synth_2 PF03142.15 OWF50247.1 - 1.4e-29 103.1 5.8 9.6e-24 83.9 0.0 2.5 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF50247.1 - 7.5e-13 48.8 3.7 7.5e-13 48.8 3.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF50247.1 - 3.4e-05 23.8 0.2 0.00012 22.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF50247.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 AAA_16 PF13191.6 OWF50247.1 - 0.068 13.6 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2371 PF10177.9 OWF50247.1 - 0.1 12.7 0.2 0.77 9.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) MSP1a PF11670.8 OWF50247.1 - 5.9 6.1 13.3 0.047 13.0 3.9 2.3 3 0 0 3 3 3 0 Major surface protein 1a (MSP1a) Insulin_TMD PF17870.1 OWF50248.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 1.9 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment DUF4448 PF14610.6 OWF50248.1 - 0.011 15.6 0.6 0.16 11.8 0.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Phage_holin_2_1 PF04971.12 OWF50248.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S Orf78 PF06024.12 OWF50248.1 - 0.043 14.1 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 OWF50248.1 - 0.073 14.0 0.2 0.55 11.1 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF202 PF02656.15 OWF50248.1 - 0.084 13.3 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF2678 PF10856.8 OWF50248.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Ly49 PF08391.10 OWF50248.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF3185 PF11381.8 OWF50248.1 - 0.19 11.8 1.4 0.75 9.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) PTP_tm PF18861.1 OWF50248.1 - 0.27 11.2 3.8 0.57 10.1 0.7 2.4 2 1 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SNF PF00209.18 OWF50249.1 - 2.3e-78 264.2 24.8 2.7e-78 264.0 24.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF50250.1 - 5.7e-133 444.4 31.8 7.2e-133 444.0 31.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Neur_chan_LBD PF02931.23 OWF50251.1 - 4.9e-38 130.7 0.2 6.8e-38 130.3 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50251.1 - 2.6e-13 50.6 12.3 5e-11 43.1 8.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2569 PF10754.9 OWF50251.1 - 3.3 8.2 14.9 0.41 11.1 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Branch PF02485.21 OWF50253.1 - 1.5e-40 139.3 3.0 1.6e-40 139.2 0.9 1.9 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Rootletin PF15035.6 OWF50254.1 - 4e-05 23.7 30.3 4e-05 23.7 30.3 4.5 2 1 1 4 4 4 2 Ciliary rootlet component, centrosome cohesion zf-C2H2 PF00096.26 OWF50254.1 - 0.0049 17.2 1.3 0.13 12.8 0.6 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type Prefoldin_2 PF01920.20 OWF50254.1 - 0.0089 16.0 7.5 0.0089 16.0 7.5 7.3 4 2 2 7 7 7 2 Prefoldin subunit DUF1664 PF07889.12 OWF50254.1 - 0.24 11.4 46.7 0.81 9.7 8.2 6.1 3 1 2 6 6 6 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OWF50254.1 - 0.27 11.8 79.2 5.8 7.4 0.1 5.7 3 1 3 6 6 6 0 Apg6 coiled-coil region Cep57_CLD PF14073.6 OWF50254.1 - 0.42 10.6 70.9 3.7 7.5 31.4 4.5 3 1 1 4 4 4 0 Centrosome localisation domain of Cep57 Syntaxin-6_N PF09177.11 OWF50254.1 - 0.49 11.0 50.0 1.4 9.5 7.3 6.7 3 1 3 6 6 6 0 Syntaxin 6, N-terminal Tropomyosin PF00261.20 OWF50254.1 - 0.83 9.0 62.7 0.032 13.6 4.0 4.8 3 1 1 4 4 4 0 Tropomyosin Mce4_CUP1 PF11887.8 OWF50254.1 - 1.5 8.2 20.7 2.4 7.5 0.6 3.8 2 1 2 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative THOC7 PF05615.13 OWF50254.1 - 2.5 8.4 56.4 1.4e+02 2.7 26.0 5.1 2 1 1 3 3 3 0 Tho complex subunit 7 FUSC PF04632.12 OWF50254.1 - 2.8 6.4 16.7 0.79 8.2 13.0 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF3800 PF12686.7 OWF50254.1 - 2.9 8.6 5.8 4.2e+02 1.6 5.8 3.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Spc7 PF08317.11 OWF50254.1 - 3.5 6.4 74.1 0.92 8.3 30.6 4.7 2 1 4 6 6 6 0 Spc7 kinetochore protein Lebercilin PF15619.6 OWF50254.1 - 3.6 7.2 75.1 2.7 7.6 32.7 4.2 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Phage_GP20 PF06810.11 OWF50254.1 - 5.1 6.9 66.9 2.7 7.8 14.6 6.9 2 1 3 6 6 6 0 Phage minor structural protein GP20 FPP PF05911.11 OWF50254.1 - 5.2 5.1 66.0 0.6 8.2 30.3 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil PALP PF00291.25 OWF50255.1 - 7.6e-68 229.1 0.0 8.7e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 OWF50255.1 - 0.053 13.4 2.2 3 7.6 0.0 2.6 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein Glycos_transf_N PF04413.16 OWF50255.1 - 0.068 12.8 0.0 0.73 9.5 0.0 2.4 2 1 1 3 3 3 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Guanylate_cyc PF00211.20 OWF50256.1 - 1e-61 207.7 0.0 2.1e-61 206.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 OWF50256.1 - 2.2e-34 119.2 0.2 3.2e-34 118.6 0.2 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 OWF50256.1 - 1.8e-31 109.4 0.0 3.6e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF50256.1 - 1.1e-22 80.7 0.0 1.6e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF50256.1 - 5.1e-06 26.1 0.7 9.2e-06 25.2 0.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 OWF50256.1 - 0.073 12.7 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein DED PF01335.21 OWF50257.1 - 6.8e-15 55.2 1.3 1.1e-12 48.1 0.0 3.5 3 0 0 3 3 3 1 Death effector domain Nucleic_acid_bd PF13820.6 OWF50257.1 - 5.2e-07 29.6 0.1 1.2e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Putative nucleic acid-binding region PHM7_cyt PF14703.6 OWF50257.1 - 9.3 6.4 8.2 0.95 9.7 0.7 2.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Fructosamin_kin PF03881.14 OWF50258.1 - 2.1e-70 237.2 0.1 4.1e-70 236.3 0.1 1.4 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OWF50258.1 - 1.6e-12 47.8 0.0 2.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 OWF50259.1 - 1.1e-56 192.1 0.0 2.1e-56 191.3 0.0 1.4 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OWF50259.1 - 2.8e-13 50.4 0.0 4.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OWF50259.1 - 0.00032 20.3 0.0 0.043 13.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family FAM47 PF14642.6 OWF50260.1 - 0.032 13.8 2.0 0.048 13.2 2.0 1.2 1 0 0 1 1 1 0 FAM47 family DUF3304 PF11745.8 OWF50260.1 - 0.49 10.8 13.2 1.2e+02 3.1 0.0 6.6 2 2 4 7 7 7 0 Protein of unknown function (DUF3304) APCDDC PF14921.6 OWF50260.1 - 6.3 6.2 65.6 2.5 7.5 0.7 10.7 1 1 9 11 11 11 0 Adenomatosis polyposis coli down-regulated 1 DUF2615 PF11027.8 OWF50261.1 - 5.6e-37 126.1 0.2 6.8e-37 125.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) FKBP_C PF00254.28 OWF50262.1 - 3.7e-22 78.5 0.0 7.9e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 OWF50262.1 - 1.2e-07 31.3 2.9 0.00015 21.6 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF50262.1 - 7.1e-06 25.8 1.0 0.013 15.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF50262.1 - 9.4e-05 22.9 0.3 0.0078 17.0 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF50262.1 - 9.9e-05 22.0 5.2 0.089 12.7 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF50262.1 - 0.00033 21.1 0.9 0.0018 18.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF50262.1 - 0.00074 19.5 1.9 0.61 10.2 0.1 2.9 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OWF50262.1 - 0.00091 19.4 3.6 0.0035 17.5 3.4 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OWF50262.1 - 0.0012 18.5 2.7 1.5 8.6 0.1 3.2 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 OWF50262.1 - 0.0017 18.9 1.2 0.021 15.5 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF50262.1 - 0.0045 17.2 2.2 0.32 11.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat IRK_C PF17655.1 OWF50263.1 - 2e-55 187.0 0.0 5e-55 185.8 0.0 1.6 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OWF50263.1 - 2.1e-46 157.2 0.3 3e-46 156.8 0.3 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans PF00520.31 OWF50263.1 - 4.2e-08 32.7 1.3 7.6e-08 31.9 1.3 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF50263.1 - 6.8e-07 29.2 4.7 1.2e-06 28.3 4.7 1.4 1 0 0 1 1 1 1 Ion channel IRK_C PF17655.1 OWF50264.1 - 3.1e-55 186.5 0.0 5.8e-55 185.6 0.0 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OWF50264.1 - 9.3e-45 151.9 3.7 1.4e-44 151.3 3.7 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OWF50264.1 - 0.076 13.0 8.1 0.16 12.0 8.1 1.5 1 0 0 1 1 1 0 Ion channel SWIRM-assoc_2 PF16496.5 OWF50264.1 - 0.16 10.8 4.2 0.21 10.4 4.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal WD40 PF00400.32 OWF50265.1 - 9.4e-13 48.4 8.4 2.1e-06 28.3 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF50265.1 - 2.4e-06 27.8 0.0 0.099 13.0 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF50265.1 - 0.00072 18.6 0.1 0.06 12.3 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 OWF50265.1 - 0.058 13.3 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_3 PF13570.6 OWF50265.1 - 0.13 12.8 0.0 0.61 10.6 0.0 2.3 1 0 0 1 1 1 0 PQQ-like domain GMP_PDE_delta PF05351.11 OWF50266.1 - 1.4e-75 252.6 1.1 1.8e-75 252.3 1.1 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit adh_short PF00106.25 OWF50267.1 - 9e-35 119.9 0.0 9.4e-28 97.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50267.1 - 7.2e-23 81.4 0.0 4.2e-21 75.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF50267.1 - 6.4e-09 36.0 0.0 8.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF50267.1 - 0.017 14.6 0.1 0.024 14.1 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hpr_kinase_C PF07475.12 OWF50267.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain GDP_Man_Dehyd PF16363.5 OWF50267.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NIF PF03031.18 OWF50268.1 - 0.00039 20.2 0.5 0.00051 19.8 0.5 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 OWF50268.1 - 0.0032 17.3 0.5 0.0049 16.7 0.5 1.4 1 1 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 OWF50268.1 - 0.034 14.2 0.8 0.18 11.9 0.8 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AAA_33 PF13671.6 OWF50268.1 - 0.034 14.3 0.2 0.089 12.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain PGP_phosphatase PF09419.10 OWF50268.1 - 0.065 12.9 0.1 2.1 7.9 0.1 2.3 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase TetR_C_9 PF14514.6 OWF50268.1 - 0.09 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Na_sulph_symp PF00939.19 OWF50269.1 - 3.2e-102 343.0 23.8 4.1e-102 342.7 23.8 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF50269.1 - 6e-36 124.2 34.3 1.1e-18 67.5 10.5 3.3 2 1 1 3 3 3 3 Citrate transporter DUF3007 PF11460.8 OWF50269.1 - 0.11 12.8 1.3 1.2 9.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Na_sulph_symp PF00939.19 OWF50270.1 - 1.8e-88 297.7 26.2 2.1e-88 297.4 26.2 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OWF50270.1 - 4.9e-45 154.0 40.9 1.4e-18 67.1 3.7 3.4 3 1 1 4 4 4 3 Citrate transporter DUF4655 PF15548.6 OWF50271.1 - 0.00055 19.0 5.6 0.023 13.7 0.6 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4655) DUF3106 PF11304.8 OWF50271.1 - 0.0031 18.0 0.0 1.2 9.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3106) Ub-RnfH PF03658.14 OWF50271.1 - 0.1 13.0 15.9 18 5.8 4.2 5.5 1 1 3 4 4 4 0 RnfH family Ubiquitin LD_cluster2 PF18163.1 OWF50271.1 - 2 7.9 6.3 3.8 7.0 0.5 2.4 1 1 2 3 3 3 0 SLOG cluster2 DUF3127 PF11325.8 OWF50271.1 - 9.6 6.5 27.3 8.4e+02 0.3 6.8 6.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3127) DUF3106 PF11304.8 OWF50272.1 - 3.6e-08 33.8 0.4 0.21 12.1 0.0 3.6 1 1 3 4 4 4 4 Protein of unknown function (DUF3106) Bactofilin PF04519.13 OWF50272.1 - 0.00015 22.0 10.3 0.73 10.2 1.4 4.3 1 1 1 2 2 2 2 Polymer-forming cytoskeletal Ub-RnfH PF03658.14 OWF50272.1 - 0.00056 20.2 25.9 0.4 11.1 3.2 7.5 1 1 3 4 4 4 2 RnfH family Ubiquitin DUF4655 PF15548.6 OWF50272.1 - 0.0038 16.3 15.1 0.18 10.7 3.3 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF4655) MgtE_N PF03448.17 OWF50272.1 - 0.33 11.6 15.8 0.72 10.5 2.8 3.3 1 1 3 4 4 4 0 MgtE intracellular N domain Gln-synt_C-ter PF18318.1 OWF50272.1 - 0.55 10.1 32.0 9.3 6.1 2.1 6.1 1 1 4 5 5 5 0 Glutamine synthetase C-terminal domain DUF3127 PF11325.8 OWF50272.1 - 5.9 7.2 41.4 32 4.9 1.6 8.9 1 1 6 7 7 7 0 Domain of unknown function (DUF3127) DUF1619 PF07773.11 OWF50273.1 - 0.0057 16.6 29.3 2.6 7.9 0.4 7.1 1 1 6 7 7 7 6 Protein of unknown function (DUF1619) ARTD15_N PF18084.1 OWF50274.1 - 4.6e-05 23.6 0.8 3.5 8.0 0.8 5.6 1 1 1 2 2 2 1 ARTD15 N-terminal domain Lipoprotein_7 PF01540.16 OWF50274.1 - 0.0006 19.2 1.8 0.38 10.0 0.2 2.7 1 1 1 2 2 2 2 Adhesin lipoprotein DUF3839 PF12943.7 OWF50274.1 - 0.051 13.0 1.2 4.4 6.7 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3839) ACT_4 PF13291.6 OWF50274.1 - 0.23 12.1 15.4 32 5.2 2.0 5.6 1 1 4 5 5 5 0 ACT domain UPF0449 PF15136.6 OWF50274.1 - 0.43 11.1 12.9 6.8 7.2 0.3 5.5 2 1 3 5 5 5 0 Uncharacterised protein family UPF0449 Plk4_PB1 PF18190.1 OWF50274.1 - 2.4 8.4 12.0 4.6 7.5 0.9 4.4 1 1 3 4 4 4 0 Polo-like Kinase 4 Polo Box 1 Prominin PF05478.11 OWF50274.1 - 4.8 5.0 16.5 2.2 6.1 5.6 2.7 1 1 2 3 3 3 0 Prominin tRNA_anti-codon PF01336.25 OWF50275.1 - 0.036 14.1 3.0 7.3 6.7 1.6 4.3 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain CAMSAP_CKK PF08683.11 OWF50275.1 - 0.054 13.6 0.5 8.1 6.6 0.1 2.5 1 1 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated Sema PF01403.19 OWF50275.1 - 0.31 9.8 4.4 2.7 6.7 0.6 2.0 1 1 1 2 2 2 0 Sema domain DUF3674 PF12426.8 OWF50275.1 - 0.48 10.5 7.9 8.1 6.6 0.1 5.1 3 3 3 6 6 6 0 RNA dependent RNA polymerase PerB PF06590.11 OWF50275.1 - 0.59 10.6 8.4 1.1 9.7 0.7 2.8 1 1 1 2 2 2 0 PerB protein Syntaxin-5_N PF11416.8 OWF50275.1 - 2.5 7.4 7.0 21 4.5 0.1 4.0 3 0 0 3 3 3 0 Syntaxin-5 N-terminal, Sly1p-binding domain DUF5090 PF17009.5 OWF50275.1 - 2.6 7.9 8.1 3.4 7.6 1.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5090) SRCR PF00530.18 OWF50276.1 - 1.1e-19 70.7 2.1 1.3e-19 70.6 2.1 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF50276.1 - 3.9e-08 33.7 2.8 6.6e-08 33.0 2.8 1.4 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain TROVE PF05731.11 OWF50277.1 - 6.4e-26 91.4 0.8 5.3e-25 88.4 0.8 2.0 1 1 0 1 1 1 1 TROVE domain Fibrinogen_C PF00147.18 OWF50277.1 - 0.013 15.3 0.0 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 Fibrinogen beta and gamma chains, C-terminal globular domain ShK PF01549.24 OWF50278.1 - 1.5e-10 41.4 39.9 3e-05 24.5 6.9 6.5 6 1 0 6 6 6 3 ShK domain-like CRAM_rpt PF07016.11 OWF50278.1 - 0.00037 20.1 52.7 0.11 12.4 0.9 8.6 2 1 6 8 8 8 6 Cysteine-rich acidic integral membrane protein precursor DUF3386 PF11866.8 OWF50279.1 - 0.0015 18.1 17.2 37 3.7 0.1 10.2 1 1 7 13 13 13 1 Protein of unknown function (DUF3386) FAM47 PF14642.6 OWF50279.1 - 1.7 8.2 57.1 27 4.2 0.5 11.0 1 1 8 12 12 12 0 FAM47 family DUF4636 PF15468.6 OWF50280.1 - 0.0021 17.8 1.2 0.0026 17.5 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4636) Corona_S2 PF01601.16 OWF50280.1 - 0.025 13.1 2.3 0.033 12.7 2.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein HSP20 PF00011.21 OWF50282.1 - 2.7e-13 49.9 1.4 3.8e-13 49.5 1.4 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family 7tm_1 PF00001.21 OWF50283.1 - 8.6e-53 179.3 9.1 1.1e-52 179.0 9.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF50283.1 - 2.8e-10 40.3 10.7 2.8e-10 40.3 10.7 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF50283.1 - 1.3e-09 38.2 4.6 1.3e-09 38.2 4.6 2.0 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF50283.1 - 0.00063 19.2 10.4 0.0016 17.8 10.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 OWF50283.1 - 0.038 13.3 15.8 0.22 10.9 15.8 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv PLAC8 PF04749.17 OWF50283.1 - 0.5 11.4 2.8 0.81 10.7 0.0 2.4 2 1 0 2 2 2 0 PLAC8 family LRR_8 PF13855.6 OWF50284.1 - 1.9e-41 139.6 57.7 5.2e-07 29.3 5.1 8.7 5 4 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 OWF50284.1 - 6.7e-33 112.2 62.3 4e-05 23.9 2.1 10.3 7 2 1 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF50284.1 - 1.8e-07 30.8 20.1 0.0068 15.9 3.7 5.3 2 2 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 OWF50284.1 - 5.8e-06 26.3 4.7 0.0044 17.0 0.4 4.3 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) COPR5 PF15340.6 OWF50284.1 - 0.083 13.5 1.8 0.18 12.4 1.8 1.6 1 0 0 1 1 1 0 Cooperator of PRMT5 family LRR_1 PF00560.33 OWF50284.1 - 1 10.1 63.9 5.5 7.9 0.1 14.9 16 1 1 17 17 17 0 Leucine Rich Repeat Pox_A_type_inc PF04508.12 OWF50285.1 - 0.00031 20.4 27.3 0.13 12.2 0.2 8.0 7 0 0 7 7 7 3 Viral A-type inclusion protein repeat DUF641 PF04859.12 OWF50285.1 - 0.00075 19.8 5.9 0.00075 19.8 5.9 10.9 3 3 9 12 12 12 3 Plant protein of unknown function (DUF641) Cnn_1N PF07989.11 OWF50285.1 - 0.0037 17.4 2.1 0.0037 17.4 2.1 12.0 5 2 4 9 9 9 2 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 OWF50285.1 - 0.0068 16.4 10.9 0.0068 16.4 10.9 9.9 2 1 8 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RP854 PF17460.2 OWF50285.1 - 0.082 12.6 2.7 4.3 7.0 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein RP854 Golgin_A5 PF09787.9 OWF50285.1 - 4.2 6.7 137.5 0.0074 15.8 16.0 7.2 1 1 5 6 6 6 0 Golgin subfamily A member 5 Nuf2 PF03800.14 OWF50286.1 - 1.2e-30 106.4 0.9 1.2e-30 106.4 0.9 2.6 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 OWF50286.1 - 1.7e-12 47.4 15.5 1.7e-12 47.4 15.5 3.8 2 1 1 3 3 3 1 Designed helical repeat protein 10 domain ING PF12998.7 OWF50286.1 - 0.0011 19.5 15.6 0.0011 19.5 15.6 3.5 2 2 1 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding T3SSipB PF16535.5 OWF50286.1 - 1.5 9.3 30.1 0.23 11.9 10.0 3.0 1 1 1 3 3 3 0 Type III cell invasion protein SipB ApoO PF09769.9 OWF50286.1 - 4.3 7.3 9.5 8.5 6.3 5.2 3.4 2 1 0 2 2 2 0 Apolipoprotein O Spc7 PF08317.11 OWF50286.1 - 5.1 5.9 53.7 1.1 8.1 14.6 3.6 1 1 2 4 4 4 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 OWF50286.1 - 8.1 5.9 39.2 0.64 9.5 10.2 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit ELP6 PF09807.9 OWF50287.1 - 5.9e-61 206.1 0.2 6.5e-61 205.9 0.2 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 OWF50287.1 - 0.00072 19.0 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 KaiC DUF835 PF05763.12 OWF50287.1 - 0.0043 16.8 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF835) ATPase_2 PF01637.18 OWF50287.1 - 0.02 14.8 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Elong_Iki1 PF10483.9 OWF50287.1 - 0.021 14.3 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 Myosin_head PF00063.21 OWF50288.1 - 6.2e-285 946.8 0.3 6.2e-285 946.8 0.3 3.0 4 0 0 4 4 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 OWF50288.1 - 5.1e-173 577.6 260.2 6.4e-173 577.3 260.2 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 OWF50288.1 - 3.7e-15 55.5 1.0 8.7e-15 54.3 1.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 OWF50288.1 - 8.1e-07 29.1 150.6 0.067 13.2 8.6 14.5 1 1 12 14 14 14 9 Protein of unknown function (DUF1664) ATG16 PF08614.11 OWF50288.1 - 2.5e-05 24.6 245.8 0.0051 17.1 28.2 10.9 2 1 10 12 12 12 4 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 OWF50288.1 - 8.9e-05 22.2 44.8 8.9e-05 22.2 44.8 10.2 2 2 6 9 9 7 3 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 OWF50288.1 - 0.00031 21.0 2.4 0.00031 21.0 2.4 11.4 1 1 10 13 13 12 3 Fibrinogen alpha/beta chain family IQ PF00612.27 OWF50288.1 - 0.00075 19.1 6.1 0.0031 17.2 0.6 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif Filament PF00038.21 OWF50288.1 - 0.0012 18.5 50.1 0.0012 18.5 50.1 7.9 1 1 5 6 6 5 2 Intermediate filament protein TPR_MLP1_2 PF07926.12 OWF50288.1 - 0.002 18.2 6.3 0.002 18.2 6.3 12.7 2 2 9 13 13 11 4 TPR/MLP1/MLP2-like protein LPP PF04728.13 OWF50288.1 - 0.011 16.1 0.1 0.011 16.1 0.1 13.5 9 5 4 13 13 12 0 Lipoprotein leucine-zipper AAA_19 PF13245.6 OWF50288.1 - 0.16 12.3 1.6 5.2 7.4 0.0 3.6 2 0 0 2 2 2 0 AAA domain DUF812 PF05667.11 OWF50288.1 - 0.21 10.4 217.6 0.18 10.6 32.5 7.1 1 1 4 5 5 5 0 Protein of unknown function (DUF812) AAA_22 PF13401.6 OWF50288.1 - 0.42 10.9 0.0 0.42 10.9 0.0 4.7 4 1 0 4 4 4 0 AAA domain Spc7 PF08317.11 OWF50288.1 - 0.66 8.8 237.1 0.005 15.8 32.2 10.4 1 1 9 11 11 11 0 Spc7 kinetochore protein AAA_16 PF13191.6 OWF50288.1 - 0.74 10.2 0.0 0.74 10.2 0.0 6.5 3 1 1 6 6 2 0 AAA ATPase domain Il2rg PF15874.5 OWF50289.1 - 7.1e-23 80.7 0.9 1e-22 80.2 0.9 1.2 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain 7tm_1 PF00001.21 OWF50290.1 - 4.6e-32 111.4 11.9 5.9e-32 111.0 11.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-LITAF-like PF10601.9 OWF50290.1 - 0.086 13.1 1.9 3.4 8.0 0.0 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain SNARE PF05739.19 OWF50290.1 - 0.21 11.6 2.3 0.74 9.9 2.3 2.1 1 0 0 1 1 1 0 SNARE domain 7TM_GPCR_Srx PF10328.9 OWF50290.1 - 0.29 10.7 11.5 0.51 9.9 9.7 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PIRT PF15099.6 OWF50290.1 - 0.58 9.7 7.6 0.15 11.7 4.3 1.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF3040 PF11239.8 OWF50290.1 - 0.74 10.1 3.0 37 4.7 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) Ctr PF04145.15 OWF50290.1 - 3.2 8.4 9.4 0.83 10.3 4.9 2.3 2 1 0 2 2 2 0 Ctr copper transporter family SEA PF01390.20 OWF50291.1 - 0.00091 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 SEA domain ETRAMP PF09716.10 OWF50291.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF927 PF06048.11 OWF50291.1 - 0.18 11.3 0.1 0.25 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) TIP41 PF04176.13 OWF50291.1 - 0.31 10.5 1.1 0.44 10.0 1.1 1.3 1 0 0 1 1 1 0 TIP41-like family AMOP PF03782.17 OWF50292.1 - 2.9e-26 92.3 7.0 7.3e-26 91.0 7.0 1.7 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 OWF50292.1 - 4.2e-23 82.1 0.6 1.4e-22 80.4 0.3 2.1 2 0 0 2 2 2 1 Nidogen-like Sushi PF00084.20 OWF50292.1 - 3.2e-15 56.5 13.2 0.00011 22.7 0.6 3.8 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) VWD PF00094.25 OWF50292.1 - 5.3e-10 39.8 0.4 5.3e-10 39.8 0.4 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain Cadherin_C_2 PF16492.5 OWF50292.1 - 0.024 15.4 0.8 0.28 12.0 0.1 3.3 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal zf-C2HC PF01530.18 OWF50292.1 - 0.13 12.5 10.5 10 6.4 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2HC type Ank_4 PF13637.6 OWF50293.1 - 2.7e-31 107.5 10.1 9.6e-07 29.2 0.1 6.5 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF50293.1 - 1.8e-29 102.2 3.5 2.3e-12 47.3 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF50293.1 - 2.4e-20 70.5 11.4 0.0082 16.6 0.1 7.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 OWF50293.1 - 4.1e-19 68.4 14.2 7.1e-07 29.4 0.1 5.3 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF50293.1 - 4.8e-18 64.7 17.4 3.1e-06 27.4 0.1 8.0 7 1 0 7 7 7 4 Ankyrin repeat SOCS_box PF07525.16 OWF50293.1 - 1.8e-08 34.6 0.8 4.6e-08 33.3 0.8 1.7 1 0 0 1 1 1 1 SOCS box JAB PF01398.21 OWF50294.1 - 1.5e-32 112.1 0.3 3e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OWF50294.1 - 1.6e-15 57.5 1.6 2.7e-15 56.8 1.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OWF50294.1 - 2.4e-06 27.3 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4525 PF15027.6 OWF50294.1 - 0.0055 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) UBA_4 PF14555.6 OWF50295.1 - 8.2e-10 38.4 0.1 1.6e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Exo_endo_phos PF03372.23 OWF50295.1 - 2.8e-07 30.3 0.0 4.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TAP_C PF03943.13 OWF50295.1 - 0.003 17.2 0.2 0.0065 16.1 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain Methyltransf_FA PF12248.8 OWF50296.1 - 8.7e-11 42.1 0.1 1.6e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase UPF0506 PF11703.8 OWF50297.1 - 0.017 15.5 6.9 0.017 15.5 6.9 2.7 1 1 1 2 2 2 0 UPF0506 ATP-synt_Z PF16594.5 OWF50298.1 - 1.1 8.8 11.9 2.8 7.5 0.4 4.3 3 1 2 5 5 5 0 Putative AtpZ or ATP-synthase-associated SRP54_N PF02881.19 OWF50300.1 - 7.4e-05 22.9 18.6 14 6.0 0.9 6.8 1 1 4 5 5 5 5 SRP54-type protein, helical bundle domain DED PF01335.21 OWF50301.1 - 0.039 14.2 0.0 0.048 14.0 0.0 1.1 1 0 0 1 1 1 0 Death effector domain Rubrerythrin PF02915.17 OWF50301.1 - 0.074 13.5 0.3 0.095 13.1 0.3 1.2 1 0 0 1 1 1 0 Rubrerythrin DUF4581 PF15167.6 OWF50301.1 - 0.091 12.9 0.1 0.14 12.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4581) Fic PF02661.18 OWF50301.1 - 0.12 13.3 0.2 0.25 12.3 0.1 1.6 1 1 1 2 2 2 0 Fic/DOC family PH PF00169.29 OWF50302.1 - 1.4e-14 54.5 0.4 2.6e-14 53.6 0.4 1.5 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 OWF50302.1 - 2e-10 40.1 1.8 3.3e-10 39.4 0.5 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OWF50302.1 - 5.9e-09 35.5 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OWF50302.1 - 6.2e-08 32.4 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 OWF50302.1 - 0.00058 20.3 2.2 0.0015 18.9 2.2 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OWF50302.1 - 0.0013 19.0 0.2 0.0029 17.9 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain bZIP_1 PF00170.21 OWF50303.1 - 0.0004 20.4 12.7 0.001 19.1 12.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF50303.1 - 0.0048 16.9 13.8 0.011 15.8 13.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF1068 PF06364.12 OWF50303.1 - 0.18 11.6 3.7 0.16 11.9 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1068) Chordopox_RPO7 PF05864.12 OWF50303.1 - 0.43 10.9 0.2 0.43 10.9 0.2 2.0 2 1 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) bZIP_1 PF00170.21 OWF50304.1 - 3.2e-06 27.2 12.3 3.2e-06 27.2 12.3 2.9 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 OWF50304.1 - 5.5e-06 26.4 7.6 1.6e-05 24.9 7.6 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF50304.1 - 0.0061 17.1 10.7 0.0061 17.1 10.7 2.5 2 1 1 3 3 3 1 bZIP Maf transcription factor TGF_beta PF00019.20 OWF50305.1 - 1e-29 103.6 1.2 1.6e-29 102.9 0.2 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 OWF50305.1 - 3e-21 76.3 5.2 2.3e-20 73.4 5.2 2.2 1 1 0 1 1 1 1 TGF-beta propeptide SMG1 PF15785.5 OWF50305.1 - 0.36 9.1 1.7 0.41 9.0 0.1 1.8 2 1 0 2 2 2 0 Serine/threonine-protein kinase smg-1 Cullin_binding PF03556.15 OWF50307.1 - 2.9e-30 105.2 0.3 4.8e-30 104.5 0.3 1.4 1 0 0 1 1 1 1 Cullin binding PP2C PF00481.21 OWF50308.1 - 7.6e-40 137.2 0.5 5e-38 131.2 0.5 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OWF50308.1 - 0.0042 16.8 0.0 0.045 13.4 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C Complex1_LYR PF05347.15 OWF50309.1 - 2.1e-10 40.5 0.3 3.7e-10 39.7 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OWF50309.1 - 0.0085 16.8 0.1 0.01 16.6 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like adh_short PF00106.25 OWF50310.1 - 1.7e-37 128.8 0.3 2.4e-37 128.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50310.1 - 3.7e-25 88.8 0.0 5e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF50310.1 - 1.8e-07 31.3 0.0 2.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF50310.1 - 3e-05 23.5 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OWF50310.1 - 0.038 13.4 0.2 0.67 9.4 0.2 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RPEL PF02755.15 OWF50312.1 - 5.9e-15 54.4 15.4 6.5e-05 22.5 3.1 3.9 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.27 OWF50312.1 - 4.7e-12 45.4 1.5 5.8e-12 45.1 0.1 1.9 2 0 0 2 2 2 1 SAP domain DUF3847 PF12958.7 OWF50312.1 - 0.14 12.3 7.7 0.4 10.8 7.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) OrfB_IS605 PF01385.19 OWF50312.1 - 8.3 6.7 7.0 22 5.3 7.0 1.6 1 0 0 1 1 1 0 Probable transposase Pkinase PF00069.25 OWF50313.1 - 6e-66 222.5 0.0 8.1e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 OWF50313.1 - 1.1e-42 144.3 1.0 4.7e-42 142.3 0.1 2.2 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 OWF50313.1 - 1.3e-31 109.8 0.1 3.7e-31 108.3 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF50313.1 - 1.7e-06 27.6 0.0 0.0024 17.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OWF50313.1 - 6e-06 25.4 0.4 9.3e-06 24.8 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF50313.1 - 0.0017 17.8 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 OWF50313.1 - 0.0019 18.5 0.8 0.0051 17.1 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.23 OWF50313.1 - 0.0071 16.3 0.5 0.041 13.8 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OWF50313.1 - 0.065 12.8 1.0 0.21 11.1 1.0 1.8 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OWF50313.1 - 0.12 12.0 0.6 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 BTB_2 PF02214.22 OWF50314.1 - 1.1e-22 80.1 0.0 1.8e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF50314.1 - 0.0088 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DCP1 PF06058.13 OWF50314.1 - 0.044 13.7 0.8 0.39 10.7 0.8 2.2 1 1 0 1 1 1 0 Dcp1-like decapping family Mt_ATP-synt_D PF05873.12 OWF50315.1 - 5.6e-37 127.0 0.6 5.6e-37 127.0 0.6 2.2 2 0 0 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) Pyr_excise PF03013.14 OWF50315.1 - 0.45 10.5 2.7 0.74 9.8 0.4 2.1 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase HlyIII PF03006.20 OWF50316.1 - 8.8e-47 159.7 28.4 1e-46 159.5 28.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related NEMP PF10225.9 OWF50316.1 - 1.5 8.4 13.1 2.3 7.8 13.1 1.4 1 0 0 1 1 1 0 NEMP family Pkinase PF00069.25 OWF50317.1 - 3.3e-41 141.4 0.1 3.3e-41 141.4 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF50317.1 - 8.4e-19 67.9 0.0 8.4e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF50317.1 - 0.0039 16.0 0.2 0.0039 16.0 0.2 3.1 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 OWF50317.1 - 0.097 12.6 10.5 1 9.2 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family SPRY PF00622.28 OWF50318.1 - 5.7e-13 49.0 1.2 1.9e-07 31.2 0.1 3.1 3 0 0 3 3 3 2 SPRY domain PHD PF00628.29 OWF50318.1 - 0.033 14.1 10.0 0.058 13.3 10.0 1.4 1 0 0 1 1 1 0 PHD-finger polyprenyl_synt PF00348.17 OWF50319.1 - 8.4e-68 228.2 0.0 9.9e-68 228.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Sec5 PF15469.6 OWF50319.1 - 0.12 12.2 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Myb_DNA-binding PF00249.31 OWF50319.1 - 0.23 11.7 0.7 0.84 9.9 0.2 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain bZIP_1 PF00170.21 OWF50320.1 - 5.4e-09 36.0 7.0 1.1e-08 35.1 7.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF50320.1 - 2.8e-06 27.8 8.9 5.3e-06 26.9 8.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OWF50320.1 - 0.0067 16.5 18.2 0.034 14.2 18.2 2.1 1 1 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.9 OWF50320.1 - 0.36 9.3 4.4 0.71 8.4 4.4 1.5 1 0 0 1 1 1 0 Macoilin family bZIP_1 PF00170.21 OWF50321.1 - 1.9e-08 34.3 18.0 1.9e-08 34.3 18.0 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF50321.1 - 3.8e-07 30.6 15.6 3.8e-07 30.6 15.6 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OWF50321.1 - 1.7e-05 24.8 18.9 1.7e-05 24.8 18.9 2.0 2 0 0 2 2 2 1 Basic region leucine zipper FapA PF03961.13 OWF50321.1 - 0.1 11.2 4.1 0.12 10.9 4.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A GCN5L1 PF06320.13 OWF50321.1 - 0.29 11.3 8.2 2.2 8.4 6.9 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) UPF0242 PF06785.11 OWF50321.1 - 0.61 10.2 8.2 1.1 9.4 8.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 OWF50321.1 - 0.92 8.8 3.2 1.2 8.4 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OWF50321.1 - 1.3 8.0 11.3 1.8 7.5 11.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 OWF50321.1 - 1.7 8.5 12.1 0.36 10.6 5.7 2.5 3 0 0 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.19 OWF50321.1 - 1.8 6.4 5.1 2.2 6.1 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 OWF50322.1 - 4.4e-07 29.9 17.9 7.2e-07 29.2 17.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF50322.1 - 0.0026 17.8 18.5 0.0041 17.2 18.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor LCD1 PF09798.9 OWF50322.1 - 0.058 11.9 0.7 0.069 11.7 0.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein bZIP_Maf PF03131.17 OWF50322.1 - 0.88 10.1 15.5 1.4 9.5 15.5 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 OWF50322.1 - 1.7 8.5 7.5 2.9 7.7 7.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Apis_Csd PF11671.8 OWF50322.1 - 2.6 8.0 8.8 5.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein TPR_MLP1_2 PF07926.12 OWF50323.1 - 0.00023 21.2 14.8 0.013 15.6 8.1 2.1 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 OWF50323.1 - 0.0066 15.6 15.0 0.0077 15.4 15.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 OWF50323.1 - 0.069 13.7 18.1 0.19 12.3 13.7 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 OWF50323.1 - 0.21 12.0 16.7 0.13 12.7 15.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) KfrA_N PF11740.8 OWF50323.1 - 0.69 10.6 21.1 60 4.4 11.6 3.4 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term ERM PF00769.19 OWF50323.1 - 1.5 8.6 25.5 0.65 9.8 14.9 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SWIRM-assoc_1 PF16495.5 OWF50323.1 - 1.9 8.5 25.7 1.8 8.6 3.6 4.0 1 1 3 4 4 4 0 SWIRM-associated region 1 CEP209_CC5 PF16574.5 OWF50323.1 - 4.5 7.5 23.6 16 5.7 2.7 3.0 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 APG6_N PF17675.1 OWF50324.1 - 0.17 12.4 11.4 0.23 12.0 11.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 OWF50324.1 - 0.18 11.1 9.6 0.2 11.0 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 OWF50324.1 - 0.67 9.7 11.6 0.8 9.5 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 OWF50324.1 - 2.9 6.9 9.3 2.9 6.9 9.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KfrA_N PF11740.8 OWF50324.1 - 8.7 7.1 12.6 10 6.8 2.2 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term bZIP_2 PF07716.15 OWF50325.1 - 1.3e-06 28.3 13.9 1.3e-06 28.3 13.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF50325.1 - 4.2e-05 23.6 14.2 9.6e-05 22.4 14.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OWF50325.1 - 0.015 15.8 11.9 0.015 15.8 11.9 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor MbeD_MobD PF04899.12 OWF50325.1 - 0.14 12.3 1.6 0.27 11.4 1.6 1.5 1 0 0 1 1 1 0 MbeD/MobD like bZIP_1 PF00170.21 OWF50326.1 - 3.5e-12 46.2 9.3 6.6e-12 45.4 9.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF50326.1 - 2e-08 34.2 9.6 3.6e-08 33.4 9.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF50326.1 - 0.0017 18.8 7.6 0.0034 17.9 7.6 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor NCKAP5 PF15246.6 OWF50326.1 - 0.0024 17.6 2.1 0.003 17.2 2.1 1.1 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein Prominin PF05478.11 OWF50326.1 - 0.022 12.7 0.8 0.024 12.6 0.8 1.2 1 0 0 1 1 1 0 Prominin Tyosinase_C PF18132.1 OWF50326.1 - 0.051 14.2 0.3 0.32 11.6 0.0 2.0 2 0 0 2 2 2 0 Tyosinase C-terminal domain Peptidase_C2 PF00648.21 OWF50327.1 - 7.7e-124 412.5 0.4 1e-123 412.1 0.4 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF50327.1 - 3.8e-47 160.1 0.0 6.9e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 OWF50327.1 - 5.8e-07 28.6 0.1 0.032 13.8 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF50327.1 - 8.2e-06 25.3 1.3 0.084 12.9 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OWF50327.1 - 0.00028 20.7 0.6 0.0011 18.8 0.5 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 OWF50327.1 - 0.2 12.1 1.1 23 5.5 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair Spec3 PF15795.5 OWF50328.1 - 4.8e-30 103.9 9.4 6.7e-30 103.5 9.4 1.2 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein Shisa PF13908.6 OWF50329.1 - 0.014 15.7 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1664 PF07889.12 OWF50330.1 - 0.047 13.7 0.0 0.054 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Peptidase_C1 PF00112.23 OWF50332.1 - 4.5e-56 190.4 2.8 6.4e-56 189.9 2.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OWF50332.1 - 6.3e-07 28.5 0.6 5.5e-05 22.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Sulfotransfer_3 PF13469.6 OWF50333.1 - 1.2e-09 38.9 0.0 1.8e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF50333.1 - 1.6e-09 37.6 1.9 3.8e-09 36.4 1.9 1.6 1 1 0 1 1 1 1 Sulfotransferase domain PilJ_C PF18223.1 OWF50333.1 - 0.061 13.8 0.5 0.83 10.2 0.2 2.2 2 0 0 2 2 2 0 Pili PilJ C-terminal domain TatD_DNase PF01026.21 OWF50334.1 - 4.3e-33 114.8 0.0 6.2e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase 53-BP1_Tudor PF09038.10 OWF50334.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor PC4 PF02229.16 OWF50334.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Sulfotransfer_1 PF00685.27 OWF50335.1 - 2.5e-13 50.1 0.5 7.3e-13 48.6 0.5 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF50335.1 - 8.1e-12 46.0 0.0 1.6e-11 45.0 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family ApeC PF16977.5 OWF50336.1 - 3.1e-55 187.3 1.8 3.1e-55 187.3 1.8 1.9 2 0 0 2 2 2 1 C-terminal domain of apextrin LEAP-2 PF07359.11 OWF50336.1 - 2.6 7.9 8.5 11 5.9 0.2 4.7 3 1 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) CLPTM1 PF05602.12 OWF50337.1 - 5.2e-128 427.7 0.1 6.2e-128 427.5 0.1 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OWF50337.1 - 0.0033 17.2 4.3 0.92 9.3 0.0 3.8 3 0 0 3 3 3 3 PQ loop repeat Lipase_GDSL_2 PF13472.6 OWF50338.1 - 6.1e-05 23.5 0.0 6.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family P4Ha_N PF08336.11 OWF50339.1 - 1.2e-34 119.2 0.1 1.4e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TcdB_N PF12918.7 OWF50339.1 - 0.023 15.0 0.1 4.4 7.7 0.0 2.2 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain IATP PF04568.12 OWF50339.1 - 0.49 10.9 1.7 0.49 10.9 0.3 1.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP ID PF18543.1 OWF50342.1 - 0.0043 17.0 0.0 16 5.6 0.0 4.3 3 2 2 5 5 5 1 Intracellular delivery domain MDD_C PF18376.1 OWF50342.1 - 0.0058 16.4 7.4 9.1 6.0 0.2 3.9 1 1 3 4 4 4 4 Mevalonate 5-diphosphate decarboxylase C-terminal domain Aminotran_4 PF01063.19 OWF50342.1 - 0.59 10.0 5.4 6.8 6.5 5.4 2.5 1 1 0 1 1 1 0 Amino-transferase class IV DUF1322 PF07032.11 OWF50342.1 - 1.1 9.9 7.1 10 6.7 0.2 4.1 1 1 3 5 5 5 0 Protein of unknown function (DUF1322) p450 PF00067.22 OWF50344.1 - 5.3e-97 325.5 0.0 6e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MtrF PF09472.10 OWF50346.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) HlyIII PF03006.20 OWF50346.1 - 0.046 13.4 7.4 0.058 13.1 7.4 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF1600 PF07667.11 OWF50346.1 - 0.1 12.8 4.7 0.16 12.2 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) Peptidase_C13 PF01650.18 OWF50347.1 - 4.7e-104 347.4 0.2 8.1e-104 346.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase C13 family Gal-3-0_sulfotr PF06990.11 OWF50348.1 - 4.7e-48 164.0 2.1 6.3e-48 163.6 2.1 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF50348.1 - 0.00071 19.6 0.3 0.003 17.5 0.2 2.3 1 1 0 1 1 1 1 Sulfotransferase family GST_C_3 PF14497.6 OWF50349.1 - 6.5e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF50349.1 - 5.4e-06 26.5 0.0 9.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF50349.1 - 3.4e-05 23.8 0.0 7.3e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF50349.1 - 0.0027 18.1 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF50349.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-TRAF PF02176.18 OWF50350.1 - 4.2e-16 59.4 24.1 1.6e-10 41.5 4.2 4.6 2 1 3 5 5 5 4 TRAF-type zinc finger Sina PF03145.16 OWF50350.1 - 1.1e-05 25.5 11.0 0.012 15.6 0.2 3.0 1 1 2 3 3 3 3 Seven in absentia protein family UPF0242 PF06785.11 OWF50350.1 - 0.011 15.9 1.8 0.021 14.9 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-TRAF_2 PF15965.5 OWF50350.1 - 0.02 15.3 7.0 0.02 15.3 7.0 3.4 1 1 2 3 3 3 0 TRAF-like zinc-finger Herpes_IE68 PF02479.16 OWF50350.1 - 0.16 11.6 0.6 0.31 10.7 0.6 1.4 1 0 0 1 1 1 0 Herpesvirus immediate early protein APG6_N PF17675.1 OWF50350.1 - 0.77 10.3 10.5 2.5 8.6 10.5 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C3HC4 PF00097.25 OWF50350.1 - 0.93 9.4 13.4 0.029 14.2 6.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.11 OWF50350.1 - 8.1 6.6 15.4 0.38 10.9 9.2 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Nup54 PF13874.6 OWF50350.1 - 8.6 6.5 10.3 6.4 6.9 1.5 2.8 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Abhydrolase_2 PF02230.16 OWF50351.1 - 1.5e-34 119.7 0.0 1.8e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OWF50351.1 - 2.3e-06 27.1 0.2 1.8e-05 24.1 0.1 2.2 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OWF50351.1 - 0.00012 22.0 0.0 0.0004 20.3 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF50351.1 - 0.0002 22.0 0.1 0.00025 21.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 OWF50351.1 - 0.0018 18.2 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 OWF50351.1 - 0.0035 17.1 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF50351.1 - 0.0045 16.7 0.1 0.0084 15.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 OWF50351.1 - 0.023 14.4 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 OWF50351.1 - 0.047 13.2 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.18 OWF50351.1 - 0.05 13.1 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 OWF50351.1 - 0.1 12.2 0.0 0.4 10.3 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Cutinase PF01083.22 OWF50351.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase PGAP1 PF07819.13 OWF50351.1 - 0.16 11.7 0.2 0.45 10.2 0.2 1.7 1 1 0 1 1 1 0 PGAP1-like protein TPR_2 PF07719.17 OWF50352.1 - 7.4e-18 63.2 18.9 0.0046 17.0 0.0 11.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF50352.1 - 3e-17 61.3 12.2 0.012 15.8 0.0 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 OWF50352.1 - 4.6e-11 43.1 13.0 0.0051 17.3 0.6 7.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF50352.1 - 2e-10 40.8 29.0 0.16 12.3 0.2 10.0 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF50352.1 - 1.4e-09 37.9 20.3 0.0031 18.2 0.1 10.5 11 1 2 13 13 11 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF50352.1 - 5.9e-09 36.0 27.1 0.012 15.8 2.2 6.2 6 1 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OWF50352.1 - 1.3e-08 34.3 31.8 0.032 14.1 0.1 9.3 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 OWF50352.1 - 1.4e-08 35.3 8.0 0.58 10.8 0.2 8.2 6 3 5 11 11 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF50352.1 - 2.2e-05 24.5 16.0 0.023 15.1 0.0 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF50352.1 - 0.00042 19.9 7.4 17 5.2 0.1 6.7 8 0 0 8 8 7 0 TPR repeat DUF3808 PF10300.9 OWF50352.1 - 0.0012 17.7 1.5 0.091 11.5 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_21 PF09976.9 OWF50352.1 - 0.0026 17.5 10.6 0.79 9.4 0.0 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 OWF50352.1 - 0.003 17.4 15.9 1.7 8.6 0.0 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF50352.1 - 0.0032 18.0 8.2 0.47 11.2 0.0 6.6 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF50352.1 - 0.0047 16.3 0.4 0.0047 16.3 0.4 4.0 5 1 0 5 5 5 1 MalT-like TPR region TPR_20 PF14561.6 OWF50352.1 - 0.025 14.9 10.4 0.79 10.1 0.1 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.10 OWF50352.1 - 0.063 12.3 4.6 2.3 7.2 0.1 3.1 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Gln_deamidase_2 PF18626.1 OWF50352.1 - 0.13 12.5 0.2 9.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Glutaminase TPR_7 PF13176.6 OWF50352.1 - 0.15 12.1 15.9 56 4.1 0.1 9.0 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF50352.1 - 1 9.6 10.7 7 6.9 0.0 5.3 6 1 2 8 8 6 0 Tetratricopeptide repeat Neur_chan_LBD PF02931.23 OWF50353.1 - 3.1e-41 141.2 1.1 4.2e-41 140.8 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50353.1 - 6.2e-12 46.1 5.6 6.2e-12 46.1 5.6 1.8 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region SSF PF00474.17 OWF50356.1 - 2.2e-06 26.8 1.8 3.3e-06 26.2 1.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5090 PF17009.5 OWF50356.1 - 0.22 11.5 7.6 0.29 11.1 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) IgGFc_binding PF17517.2 OWF50357.1 - 3.3e-68 230.1 2.8 5.4e-68 229.4 0.9 2.2 2 0 0 2 2 2 1 IgGFc binding protein TSP_1 PF00090.19 OWF50357.1 - 4.9e-54 180.3 118.5 6.2e-09 35.9 5.0 9.5 9 0 0 9 9 9 7 Thrombospondin type 1 domain VWD PF00094.25 OWF50357.1 - 2.8e-24 86.2 0.6 2.8e-24 86.2 0.6 2.9 2 0 0 2 2 2 1 von Willebrand factor type D domain Kringle PF00051.18 OWF50357.1 - 4.6e-23 81.3 21.8 8.3e-15 54.9 9.2 5.8 5 1 0 5 5 5 2 Kringle domain Methyltransf_FA PF12248.8 OWF50357.1 - 2.5e-18 66.3 0.3 2.8e-17 62.9 0.2 2.8 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase C8 PF08742.11 OWF50357.1 - 6.1e-09 36.2 1.8 6.1e-09 36.2 1.8 3.4 2 1 1 3 3 3 1 C8 domain TIL PF01826.17 OWF50357.1 - 2.6e-07 30.8 10.8 2.6e-07 30.8 10.8 8.8 7 2 1 8 8 8 1 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 OWF50357.1 - 0.00082 19.5 7.6 0.00082 19.5 7.6 3.7 2 0 0 2 2 2 1 EGF domain Kringle PF00051.18 OWF50358.1 - 1.1e-27 96.2 30.2 2.1e-16 60.0 8.5 4.0 3 1 0 3 3 3 2 Kringle domain VWD PF00094.25 OWF50358.1 - 1.6e-26 93.4 3.8 1.6e-26 93.4 3.8 2.0 3 0 0 3 3 3 1 von Willebrand factor type D domain TIL PF01826.17 OWF50358.1 - 6.9e-17 61.4 33.4 6e-10 39.2 12.3 7.3 7 1 0 7 7 7 2 Trypsin Inhibitor like cysteine rich domain C8 PF08742.11 OWF50358.1 - 1.9e-08 34.6 1.6 1.9e-08 34.6 1.6 5.4 6 2 0 6 6 6 1 C8 domain TILa PF12714.7 OWF50358.1 - 1.2e-05 25.1 4.3 1.2e-05 25.1 4.3 6.4 5 2 1 6 6 6 2 TILa domain EGF_3 PF12947.7 OWF50358.1 - 1.3e-05 25.3 16.6 0.00018 21.6 4.0 8.0 7 2 0 7 7 7 2 EGF domain Plasmod_Pvs28 PF06247.11 OWF50358.1 - 0.0077 16.5 6.8 0.0077 16.5 6.8 8.0 8 3 1 9 9 9 2 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 OWF50358.1 - 1.2 9.3 33.6 0.66 10.1 2.3 6.2 6 0 0 6 6 6 0 MSP1 EGF domain 1 VWD PF00094.25 OWF50359.1 - 1.5e-26 93.5 3.3 1.5e-26 93.5 3.3 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain Gal_Lectin PF02140.18 OWF50359.1 - 1.6e-20 73.3 1.4 1.6e-20 73.3 1.4 4.9 4 1 3 7 7 7 1 Galactose binding lectin domain TIL PF01826.17 OWF50359.1 - 4.2e-10 39.7 12.3 4.2e-10 39.7 12.3 5.3 5 0 0 5 5 5 1 Trypsin Inhibitor like cysteine rich domain C8 PF08742.11 OWF50359.1 - 1.2e-08 35.3 1.5 1.2e-08 35.3 1.5 4.4 6 1 0 6 6 6 1 C8 domain TILa PF12714.7 OWF50359.1 - 8.7e-06 25.6 4.4 8.7e-06 25.6 4.4 5.0 5 1 0 5 5 5 1 TILa domain EGF_3 PF12947.7 OWF50359.1 - 0.00013 22.1 4.0 0.00013 22.1 4.0 5.9 4 1 0 4 4 4 1 EGF domain Plasmod_Pvs28 PF06247.11 OWF50359.1 - 0.0014 18.9 4.0 0.0014 18.9 4.0 5.1 4 2 0 4 4 4 2 Pvs28 EGF domain DUF3395 PF11875.8 OWF50359.1 - 0.038 13.9 0.0 7.2 6.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3395) Homeodomain PF00046.29 OWF50360.1 - 8.1e-20 70.4 2.4 1.4e-19 69.7 2.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF50360.1 - 0.0092 15.9 0.3 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 Homeobox KN domain AAA_33 PF13671.6 OWF50361.1 - 1.5e-05 25.2 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PAS_3 PF08447.12 OWF50362.1 - 1.2e-22 80.0 0.2 2.9e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 OWF50362.1 - 4.9e-20 71.7 1.4 6.6e-17 61.7 0.3 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 OWF50362.1 - 1e-17 64.1 0.0 9.9e-08 32.0 0.0 2.8 1 1 2 3 3 3 2 PAS fold PAS_9 PF13426.7 OWF50362.1 - 7.7e-11 42.2 0.1 0.00015 21.9 0.1 2.8 2 1 0 2 2 2 2 PAS domain HIF-1a_CTAD PF08778.10 OWF50362.1 - 4.4e-07 29.4 0.0 9.7e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.8 OWF50362.1 - 6.5e-07 28.6 4.2 4.2e-06 26.1 3.8 2.5 2 0 0 2 2 2 1 Hypoxia-inducible factor-1 PAS_4 PF08448.10 OWF50362.1 - 3.3e-06 27.3 0.0 0.075 13.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold DUF2200 PF09966.9 OWF50362.1 - 0.083 13.0 0.1 0.33 11.1 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) HLH PF00010.26 OWF50362.1 - 0.083 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain I_LWEQ PF01608.17 OWF50362.1 - 0.19 12.0 1.2 0.39 10.9 1.2 1.5 1 0 0 1 1 1 0 I/LWEQ domain Cys_knot PF00007.22 OWF50363.1 - 3.4e-09 36.9 5.8 4.7e-09 36.5 5.8 1.2 1 0 0 1 1 1 1 Cystine-knot domain NAM-associated PF14303.6 OWF50364.1 - 0.13 13.0 5.4 0.23 12.1 5.4 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SRP-alpha_N PF04086.13 OWF50364.1 - 0.61 10.0 6.6 0.76 9.6 6.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-C2H2 PF00096.26 OWF50366.1 - 1.3e-10 41.1 54.7 6.6e-05 23.2 7.2 5.8 6 0 0 6 6 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF50366.1 - 9.6e-10 38.4 19.2 8.2e-06 26.0 3.9 6.5 8 0 0 8 8 7 3 Zinc-finger double domain zf-met PF12874.7 OWF50366.1 - 1.8e-09 37.6 18.8 0.039 14.4 0.2 4.9 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OWF50366.1 - 5.9e-08 32.9 39.3 0.0038 17.9 2.2 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF50366.1 - 0.00015 21.9 17.8 0.27 11.6 0.3 4.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 OWF50366.1 - 0.0076 16.1 16.9 0.077 12.9 0.5 4.2 4 0 0 4 4 4 2 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 OWF50366.1 - 0.15 12.4 22.0 0.29 11.5 9.8 5.0 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 OWF50366.1 - 0.17 12.2 3.9 11 6.3 0.5 3.2 3 0 0 3 3 3 0 zinc-finger-containing domain 7tm_4 PF13853.6 OWF50366.1 - 0.2 11.4 0.6 0.3 10.8 0.6 1.2 1 0 0 1 1 1 0 Olfactory receptor Trypan_PARP PF05887.11 OWF50366.1 - 0.43 10.6 6.8 1.7 8.6 6.8 2.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HypA PF01155.19 OWF50366.1 - 0.72 9.9 5.6 0.85 9.7 1.0 3.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.5 OWF50366.1 - 4.2 7.2 16.6 0.94 9.3 1.8 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type FAM176 PF14851.6 OWF50366.1 - 8.3 6.1 23.6 0.77 9.4 3.1 3.5 3 0 0 3 3 3 0 FAM176 family zf_UBZ PF18439.1 OWF50366.1 - 9.8 5.9 7.9 3.7 7.2 0.5 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Homeodomain PF00046.29 OWF50367.1 - 3.7e-22 77.9 3.2 7.3e-22 77.0 3.2 1.5 1 0 0 1 1 1 1 Homeodomain SatD PF16264.5 OWF50367.1 - 0.081 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 SatD family (SatD) CPSF73-100_C PF11718.8 OWF50367.1 - 2 7.9 5.8 8.2 5.9 5.8 1.8 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MULE PF10551.9 OWF50368.1 - 4.1e-06 27.1 0.0 7.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FLYWCH PF04500.16 OWF50368.1 - 4.7e-06 26.6 0.3 1.4e-05 25.1 0.2 1.8 2 0 0 2 2 2 1 FLYWCH zinc finger domain DDE_Tnp_ISL3 PF01610.17 OWF50368.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposase Ribosomal_S5_C PF03719.15 OWF50369.1 - 2.2e-19 68.7 0.1 4.1e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 OWF50369.1 - 1.2e-10 41.2 2.3 1.4e-10 41.0 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain PNPase_C PF12111.8 OWF50369.1 - 4.1 6.9 4.8 1.3 8.5 0.3 2.2 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Cupin_8 PF13621.6 OWF50370.1 - 0.03 14.0 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 Cupin-like domain TPR_14 PF13428.6 OWF50371.1 - 1.1e-11 44.5 8.1 0.43 11.5 0.0 7.4 6 2 2 8 8 8 3 Tetratricopeptide repeat NRDE-2 PF08424.10 OWF50371.1 - 2.9e-06 26.7 8.8 0.0018 17.5 0.0 4.1 3 2 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 OWF50371.1 - 0.0004 20.8 1.4 1.5 9.4 0.2 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OWF50371.1 - 0.0079 15.4 4.7 2.7 7.1 0.1 4.1 2 2 1 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OWF50371.1 - 0.0079 16.2 17.9 0.9 9.5 0.2 5.8 4 4 2 6 6 6 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 OWF50371.1 - 0.024 15.3 6.5 1.3 9.7 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat FliG_N PF14842.6 OWF50371.1 - 0.076 13.6 1.6 0.14 12.7 0.1 2.3 2 0 0 2 2 2 0 FliG N-terminal domain HAT PF02184.16 OWF50371.1 - 3.8 7.5 10.8 2.5 8.1 0.1 4.5 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat Suf PF05843.14 OWF50371.1 - 4.5 7.2 15.2 0.11 12.4 0.9 3.8 3 2 1 4 4 4 0 Suppressor of forked protein (Suf) MARVEL PF01284.23 OWF50372.1 - 1.4e-05 25.2 14.2 4.2e-05 23.6 14.2 1.7 1 1 0 1 1 1 1 Membrane-associating domain CbiM PF01891.16 OWF50372.1 - 0.001 19.0 4.8 0.0018 18.1 4.7 1.7 1 1 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region EamA PF00892.20 OWF50372.1 - 0.0015 18.7 15.4 0.0025 18.0 3.4 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF1418 PF07214.12 OWF50372.1 - 1 9.2 0.1 1 9.2 0.1 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1418) Zap1_zf2 PF18217.1 OWF50373.1 - 0.065 13.2 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Zap1 zinc finger 2 LRR_4 PF12799.7 OWF50374.1 - 0.0039 17.6 1.7 1.7 9.2 0.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) MCU PF04678.13 OWF50374.1 - 0.35 10.9 2.7 0.22 11.6 0.7 1.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter SpoU_methylase PF00588.19 OWF50375.1 - 2.6e-26 92.5 0.0 6e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family IPK PF03770.16 OWF50375.1 - 0.18 11.6 0.1 0.61 9.9 0.1 1.9 1 0 0 1 1 1 0 Inositol polyphosphate kinase DUF902 PF06001.13 OWF50375.1 - 1 9.9 4.3 2.6e+02 2.2 0.1 4.9 2 1 4 6 6 6 0 Domain of Unknown Function (DUF902) Cofilin_ADF PF00241.20 OWF50376.1 - 3.6e-25 88.1 0.1 4.6e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EGF PF00008.27 OWF50377.1 - 2e-07 31.2 8.4 2e-07 31.2 8.4 4.4 4 0 0 4 4 4 3 EGF-like domain SKG6 PF08693.10 OWF50377.1 - 1.2e-06 27.8 7.7 2.8e-06 26.6 7.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain hEGF PF12661.7 OWF50377.1 - 7.7e-06 26.4 5.5 7.7e-06 26.4 5.5 4.6 3 1 1 4 4 4 1 Human growth factor-like EGF DUF3377 PF11857.8 OWF50377.1 - 0.00022 21.1 0.1 0.00056 19.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) EGF_2 PF07974.13 OWF50377.1 - 0.022 15.1 45.0 0.059 13.8 11.2 3.8 3 0 0 3 3 3 0 EGF-like domain EGF_CA PF07645.15 OWF50377.1 - 0.04 14.1 35.8 0.047 13.9 6.6 3.7 3 0 0 3 3 3 0 Calcium-binding EGF domain DUF4448 PF14610.6 OWF50377.1 - 0.058 13.2 0.2 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) cEGF PF12662.7 OWF50377.1 - 1.3 9.0 21.0 0.39 10.7 3.5 4.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like Insulin_TMD PF17870.1 OWF50377.1 - 8.5 6.5 7.6 2.4 8.3 3.8 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment 7tm_3 PF00003.22 OWF50378.1 - 6.5e-41 140.6 25.0 6.5e-41 140.6 25.0 1.7 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR hEGF PF12661.7 OWF50378.1 - 0.6 10.8 5.1 0.25 12.0 1.3 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF Ank_2 PF12796.7 OWF50379.1 - 3.5e-25 88.4 6.8 6.2e-08 33.1 0.1 5.0 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50379.1 - 1.1e-21 76.9 2.3 7e-08 32.9 0.0 6.2 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF50379.1 - 2.3e-19 68.9 1.4 0.2 12.1 0.1 8.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 OWF50379.1 - 5.7e-16 58.4 7.3 1.9e-06 28.0 0.4 5.1 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50379.1 - 1.2e-14 53.0 7.6 0.029 14.9 0.1 8.5 8 1 0 8 8 8 4 Ankyrin repeat DUF2757 PF10955.8 OWF50379.1 - 0.0087 16.3 0.1 8.3 6.7 0.0 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2757) DUF3447 PF11929.8 OWF50379.1 - 0.37 10.8 13.6 2.6 8.1 0.5 4.7 3 1 2 5 5 5 0 Domain of unknown function (DUF3447) Abhydrolase_3 PF07859.13 OWF50380.1 - 5.8e-57 192.9 0.0 7.3e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF50380.1 - 1.8e-05 24.4 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OWF50380.1 - 3.3e-05 23.0 1.2 9.8e-05 21.4 1.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 OWF50380.1 - 0.022 14.3 0.2 0.15 11.6 0.2 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 OWF50380.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OWF50380.1 - 0.17 11.1 0.0 0.34 10.2 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 TMEM72 PF16054.5 OWF50381.1 - 8.6e-22 77.7 6.3 1.2e-21 77.2 6.3 1.1 1 0 0 1 1 1 1 Transmembrane protein family 72 COPI_assoc PF08507.10 OWF50381.1 - 0.0092 16.0 6.4 0.077 13.0 6.4 2.2 1 1 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 OWF50381.1 - 0.01 16.1 5.6 0.01 16.1 5.6 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein CG6151-P DUF1980 PF09323.10 OWF50381.1 - 0.039 13.9 0.8 0.15 11.9 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DSRB PF10781.9 OWF50381.1 - 0.069 12.8 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Dextransucrase DSRB fn3 PF00041.21 OWF50382.1 - 2.8e-11 43.6 4.5 8.5e-05 22.8 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF50382.1 - 0.0063 17.1 3.1 0.63 10.7 0.2 3.3 2 1 1 3 3 3 1 Purple acid Phosphatase, N-terminal domain FTHFS PF01268.19 OWF50383.1 - 1.8e-260 864.9 0.0 2.7e-260 864.3 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OWF50383.1 - 1.1e-66 223.1 0.3 1.1e-66 223.1 0.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OWF50383.1 - 1.2e-31 109.3 0.4 3.1e-31 108.0 0.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GST_N_3 PF13417.6 OWF50384.1 - 3.3e-17 62.6 0.0 7.9e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF50384.1 - 5.9e-15 55.4 0.0 9.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF50384.1 - 2.4e-13 50.2 0.0 3.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF50384.1 - 3.2e-06 27.3 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF50384.1 - 2.8e-05 24.2 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF50384.1 - 0.00037 20.5 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OWF50384.1 - 0.05 14.2 0.0 0.09 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OWF50384.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin Methyltransf_22 PF13383.6 OWF50385.1 - 0.022 14.3 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OWF50385.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DM PF00751.18 OWF50386.1 - 2.8e-17 62.3 14.2 4.8e-17 61.6 14.2 1.4 1 0 0 1 1 1 1 DM DNA binding domain DSX_dimer PF08828.10 OWF50386.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Doublesex dimerisation domain zf-CCHC_3 PF13917.6 OWF50388.1 - 0.1 12.6 4.3 0.15 12.0 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle CBM9_1 PF06452.11 OWF50389.1 - 6.4e-08 32.7 1.9 2.1e-07 31.0 1.9 1.8 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like HPD PF05044.12 OWF50390.1 - 4.7e-77 257.1 4.1 1.2e-76 255.8 4.1 1.7 1 0 0 1 1 1 1 Homeo-prospero domain 2-oxoacid_dh PF00198.23 OWF50391.1 - 6.6e-80 267.9 0.1 8.5e-80 267.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OWF50391.1 - 5.3e-21 74.2 0.1 8.6e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OWF50391.1 - 0.00018 21.3 0.0 0.0019 18.0 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 OWF50391.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion QRPTase_N PF02749.16 OWF50391.1 - 0.041 14.0 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain MSP1_C PF07462.11 OWF50391.1 - 0.21 10.2 1.0 0.31 9.7 1.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus adh_short PF00106.25 OWF50392.1 - 8.8e-39 133.0 0.7 6.9e-38 130.1 0.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50392.1 - 1.8e-24 86.6 0.2 8.8e-24 84.3 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF50392.1 - 2.9e-09 37.1 0.2 6e-09 36.1 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF50392.1 - 1.1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF50392.1 - 3.4e-05 23.4 0.0 4.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase HECT_2 PF09814.9 OWF50392.1 - 0.0039 16.1 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding 2-Hacid_dh_C PF02826.19 OWF50392.1 - 0.031 13.6 0.2 0.11 11.9 0.1 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OWF50392.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_transf_4 PF13439.6 OWF50392.1 - 0.097 12.7 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Reprolysin_5 PF13688.6 OWF50393.1 - 5.7e-28 98.4 0.2 2e-27 96.6 0.2 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OWF50393.1 - 1.6e-25 90.1 1.4 2.3e-25 89.7 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF50393.1 - 3.7e-12 46.9 0.1 1.6e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OWF50393.1 - 3.2e-09 37.5 23.2 3.2e-09 37.5 23.2 3.4 2 1 0 2 2 1 1 Disintegrin Pep_M12B_propep PF01562.19 OWF50393.1 - 9.9e-06 25.8 0.0 2.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 OWF50393.1 - 2.4e-05 24.1 0.5 5.4e-05 22.9 0.5 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 OWF50393.1 - 0.0009 19.2 0.0 0.0009 19.2 0.0 4.2 4 1 0 4 4 4 2 Reprolysin (M12B) family zinc metalloprotease Phage_Gp23 PF10669.9 OWF50393.1 - 0.059 13.7 1.4 0.14 12.5 1.4 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) UPF0370 PF13980.6 OWF50393.1 - 0.25 11.4 1.3 0.57 10.3 1.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF3810 PF12725.7 OWF50393.1 - 0.63 9.3 5.0 2.5 7.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) ETRAMP PF09716.10 OWF50393.1 - 2.2 8.4 5.9 0.96 9.6 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sde2_N_Ubi PF13019.6 OWF50394.1 - 2.1e-24 86.2 1.4 5e-24 85.0 1.4 1.6 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 OWF50394.1 - 9.7e-20 70.0 0.9 9.7e-20 70.0 0.9 1.8 2 0 0 2 2 2 1 Telomere stability C-terminal RecC_C PF17946.1 OWF50394.1 - 0.044 13.6 1.6 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 RecC C-terminal domain SAP PF02037.27 OWF50394.1 - 0.099 12.4 0.9 0.35 10.7 0.9 2.0 1 0 0 1 1 1 0 SAP domain Redoxin PF08534.10 OWF50395.1 - 1.1e-31 109.5 0.0 1.4e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OWF50395.1 - 2.8e-10 40.2 0.0 3.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family TPR_17 PF13431.6 OWF50396.1 - 1.5e-06 28.1 1.6 0.00047 20.3 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF50396.1 - 9.8e-06 26.0 2.4 1.8e-05 25.1 0.9 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF50396.1 - 2.4e-05 24.1 8.9 0.095 12.9 0.2 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF50396.1 - 3.4e-05 23.5 15.9 0.054 13.3 0.2 4.3 4 1 0 4 4 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF50396.1 - 6.1e-05 23.2 7.4 9.3e-05 22.6 1.7 2.6 2 2 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OWF50396.1 - 0.0018 18.3 0.7 0.15 12.2 0.1 2.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OWF50396.1 - 0.0023 18.2 5.0 0.0079 16.5 2.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF50396.1 - 0.0023 18.5 3.3 0.14 12.9 0.7 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OWF50396.1 - 0.0056 16.7 0.7 0.0056 16.7 0.7 1.8 2 0 0 2 2 2 1 Putative TPR-like repeat Sec16_C PF12931.7 OWF50396.1 - 0.046 13.4 0.8 0.058 13.0 0.8 1.1 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_14 PF13428.6 OWF50396.1 - 0.056 14.3 1.3 13 6.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF50396.1 - 0.082 13.0 3.7 0.56 10.4 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OWF50396.1 - 0.1 12.5 5.9 4.9 7.2 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF50396.1 - 0.14 12.8 5.6 7.9 7.4 0.2 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Sas6_CC PF18594.1 OWF50396.1 - 0.29 10.9 7.6 0.07 12.9 2.7 2.3 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain TPR_8 PF13181.6 OWF50396.1 - 1.1 9.7 4.6 1.2 9.5 0.1 3.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OWF50396.1 - 1.5 8.6 6.4 1.8 8.3 0.1 3.5 4 1 1 5 5 5 0 TPR repeat AMP-binding PF00501.28 OWF50397.1 - 9.9e-98 327.5 0.0 1.3e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF50397.1 - 2.6e-18 66.7 1.7 4.1e-18 66.1 0.2 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF50398.1 - 5.6e-97 325.0 0.0 7.6e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF50398.1 - 2.4e-17 63.7 0.0 9.1e-17 61.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF50399.1 - 5e-43 147.3 0.0 6e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF50399.1 - 1.3e-18 67.7 0.0 3.6e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF50400.1 - 5.1e-100 335.0 0.0 6.3e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF50400.1 - 7.2e-17 62.1 0.0 2e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_Mga PF08280.11 OWF50400.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain AMP-binding PF00501.28 OWF50401.1 - 1.7e-99 333.3 0.0 2.1e-99 333.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF50401.1 - 4.1e-18 66.1 0.0 9.6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF50402.1 - 3.3e-94 315.9 0.0 4e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF50402.1 - 5.5e-12 46.5 0.0 1.4e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ac76 PF05814.11 OWF50403.1 - 0.46 10.5 1.6 16 5.6 0.4 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) Rota_NSP4 PF01452.16 OWF50403.1 - 2.5 7.8 5.1 3.1 7.4 1.3 2.7 2 1 0 2 2 2 0 Rotavirus non structural protein TTKRSYEDQ PF10212.9 OWF50404.1 - 5.8e-194 645.9 25.0 5.8e-194 645.9 25.0 2.9 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein KLRAQ PF10205.9 OWF50404.1 - 6.9e-31 106.5 4.2 6.9e-31 106.5 4.2 5.6 5 1 0 5 5 4 1 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.7 OWF50404.1 - 0.0036 17.4 4.8 0.0036 17.4 4.8 5.5 5 1 0 5 5 5 3 Tropomyosin like CENP-F_leu_zip PF10473.9 OWF50404.1 - 0.0066 16.5 13.8 0.0066 16.5 13.8 5.5 6 0 0 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 OWF50404.1 - 0.018 15.3 10.4 0.018 15.3 10.4 6.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OWF50404.1 - 0.64 10.7 40.5 0.059 14.0 7.9 6.5 4 2 0 5 5 5 0 SlyX DHR10 PF18595.1 OWF50404.1 - 1.2 9.2 73.3 0.13 12.3 11.9 6.5 5 1 1 6 6 6 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 OWF50404.1 - 1.4 9.3 62.3 0.28 11.6 12.0 5.0 3 2 2 5 5 5 0 Fez1 Filament PF00038.21 OWF50404.1 - 3.8 7.0 60.0 0.13 11.8 27.2 4.0 5 1 0 5 5 5 0 Intermediate filament protein RuvX PF03652.15 OWF50404.1 - 4 7.8 7.0 3 8.2 0.2 3.6 2 1 1 3 3 3 0 Holliday junction resolvase Packaging_FI PF14000.6 OWF50404.1 - 5.7 7.4 8.9 5.4 7.5 0.1 3.4 3 0 0 3 3 3 0 DNA packaging protein FI DASH_Dam1 PF08653.10 OWF50404.1 - 6.7 6.6 9.6 2 8.3 0.5 4.6 5 0 0 5 5 5 0 DASH complex subunit Dam1 HSP70 PF00012.20 OWF50405.1 - 2.6e-09 35.9 0.1 4.1e-08 31.9 0.1 2.1 1 1 0 1 1 1 1 Hsp70 protein DDR PF08841.10 OWF50405.1 - 0.0081 15.2 0.4 0.2 10.6 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain MreB_Mbl PF06723.13 OWF50405.1 - 0.021 13.7 4.5 0.45 9.3 0.1 2.9 2 1 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 OWF50406.1 - 5.3e-09 34.8 0.1 8.8e-08 30.8 0.1 2.1 1 1 0 1 1 1 1 Hsp70 protein DDR PF08841.10 OWF50406.1 - 0.011 14.7 0.3 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MreB_Mbl PF06723.13 OWF50406.1 - 0.023 13.5 4.2 0.73 8.6 0.1 2.9 2 1 0 2 2 2 0 MreB/Mbl protein TSP_1 PF00090.19 OWF50408.1 - 2.8e-60 200.3 122.5 2.8e-12 46.7 10.1 7.5 8 0 0 8 8 8 6 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF50408.1 - 4.4e-07 30.0 9.6 4.4e-07 30.0 9.6 5.1 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A EGF PF00008.27 OWF50408.1 - 2.8e-05 24.3 10.9 2.8e-05 24.3 10.9 5.1 4 0 0 4 4 4 1 EGF-like domain Rhodanese PF00581.20 OWF50408.1 - 0.26 11.8 2.7 13 6.4 0.0 4.3 5 0 0 5 5 5 0 Rhodanese-like domain DUF4177 PF13783.6 OWF50409.1 - 3.9e-05 23.9 0.2 0.036 14.3 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4177) Memo PF01875.17 OWF50410.1 - 2.5e-83 279.3 0.0 2.9e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein HXXSHH PF07586.11 OWF50410.1 - 0.051 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Med29 PF11568.8 OWF50412.1 - 1.3e-44 151.8 0.3 1.6e-44 151.5 0.3 1.1 1 0 0 1 1 1 1 Mediator complex subunit 29 WASH-7_mid PF14744.6 OWF50412.1 - 0.02 14.0 0.1 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 Dynamin_M PF01031.20 OWF50412.1 - 0.049 12.8 0.5 0.1 11.8 0.5 1.8 1 1 0 1 1 1 0 Dynamin central region DUF4842 PF16130.5 OWF50412.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4842) RII_binding_1 PF10522.9 OWF50413.1 - 0.16 12.3 0.8 0.38 11.1 0.8 1.7 1 0 0 1 1 1 0 RII binding domain NACHT_N PF17100.5 OWF50413.1 - 3.9 7.3 6.0 7.7 6.3 1.9 2.2 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase 2OG-FeII_Oxy_2 PF13532.6 OWF50414.1 - 6.8e-34 117.8 0.1 2.5e-33 115.9 0.1 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zip PF02535.22 OWF50416.1 - 5e-53 180.5 11.9 1.2e-42 146.3 5.5 2.6 3 1 1 4 4 4 2 ZIP Zinc transporter Wyosine_form PF08608.12 OWF50417.1 - 0.1 12.9 2.9 2.2e+02 2.3 0.0 5.6 4 3 2 6 6 6 0 Wyosine base formation Drf_FH1 PF06346.12 OWF50417.1 - 0.55 9.9 34.0 16 5.2 14.8 2.7 1 1 1 2 2 2 0 Formin Homology Region 1 Rhodanese_C PF12368.8 OWF50417.1 - 6.9 7.1 11.9 17 5.9 0.0 4.5 2 2 2 4 4 4 0 Rhodanase C-terminal DUF4821 PF16092.5 OWF50418.1 - 2.5e-105 351.9 0.4 2.1e-96 322.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 OWF50418.1 - 7.7e-06 25.4 0.0 4.6e-05 22.8 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Dsh_C PF12316.8 OWF50418.1 - 4.7 7.6 16.8 10 6.4 16.8 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal HAT PF02184.16 OWF50419.1 - 1.5e-33 114.5 73.5 7.2e-18 64.3 1.9 13.7 13 2 0 13 13 13 6 HAT (Half-A-TPR) repeat Suf PF05843.14 OWF50419.1 - 2.6e-14 53.9 27.5 0.00015 21.8 5.3 5.8 2 2 3 5 5 5 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OWF50419.1 - 5.4e-14 51.7 20.6 0.4 11.6 0.0 10.8 6 5 5 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF50419.1 - 2e-10 41.0 0.0 0.029 14.9 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF50419.1 - 2.8e-07 30.4 0.2 0.015 15.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF50419.1 - 3.8e-05 23.5 4.6 15 6.0 0.1 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF50419.1 - 0.00012 22.3 3.4 0.68 10.3 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OWF50419.1 - 0.00022 21.2 25.0 0.019 14.9 1.2 6.7 5 2 1 6 6 6 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 OWF50419.1 - 0.0017 19.0 0.6 5.5 7.7 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF50419.1 - 0.022 15.0 1.3 2.9 8.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat QIL1 PF15884.5 OWF50419.1 - 0.13 12.9 0.9 15 6.3 0.0 4.1 3 1 1 4 4 4 0 MICOS complex subunit MIC13, QIL1 TPR_6 PF13174.6 OWF50419.1 - 0.47 11.2 14.1 43 5.1 0.0 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF50419.1 - 2 8.6 6.5 33 4.7 0.6 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 OWF50419.1 - 3 8.0 25.3 1.4 9.0 0.2 7.0 4 4 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Kazal_2 PF07648.15 OWF50420.1 - 4.6e-09 36.3 4.6 4.6e-09 36.3 4.6 3.7 5 1 0 5 5 5 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF50420.1 - 9.9e-06 25.5 7.3 9.9e-06 25.5 7.3 2.5 2 2 0 2 2 2 1 Kazal-type serine protease inhibitor domain IGFBP PF00219.18 OWF50420.1 - 0.0019 18.8 14.5 0.0019 18.8 14.5 2.6 2 1 0 2 2 2 1 Insulin-like growth factor binding protein SR-25 PF10500.9 OWF50420.1 - 0.084 12.5 19.2 0.13 11.8 19.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acetyltransf_1 PF00583.25 OWF50421.1 - 3.4e-13 49.9 0.0 4.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF50421.1 - 1.6e-10 41.0 0.1 2.2e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF50421.1 - 7.8e-09 35.8 0.1 1.1e-08 35.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF50421.1 - 6.9e-08 32.4 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OWF50421.1 - 0.00064 19.8 0.0 0.0013 18.9 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OWF50421.1 - 0.027 14.6 0.1 0.034 14.3 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF832 PF05734.11 OWF50421.1 - 0.17 11.3 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) DUF4485 PF14846.6 OWF50422.1 - 2.6e-28 97.9 0.0 2.6e-28 97.9 0.0 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF4485) Tup_N PF08581.10 OWF50422.1 - 0.016 15.5 7.2 0.016 15.5 7.2 11.6 4 3 7 12 12 12 0 Tup N-terminal FAM184 PF15665.5 OWF50422.1 - 7.1 6.4 165.2 0.74 9.6 19.2 6.6 1 1 6 7 7 7 0 Family with sequence similarity 184, A and B WH1 PF00568.23 OWF50423.1 - 1.1e-32 112.2 0.4 1.5e-32 111.8 0.4 1.1 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 OWF50423.1 - 3.4e-17 61.7 3.4 3.4e-17 61.7 3.4 1.9 2 0 0 2 2 2 1 VASP tetramerisation domain Ran_BP1 PF00638.18 OWF50423.1 - 0.00011 22.5 0.1 0.00025 21.3 0.1 1.5 1 1 0 1 1 1 1 RanBP1 domain HI0933_like PF03486.14 OWF50423.1 - 0.32 9.6 5.7 0.58 8.8 5.7 1.3 1 0 0 1 1 1 0 HI0933-like protein Serglycin PF04360.12 OWF50423.1 - 0.94 9.4 3.9 2.1 8.3 3.9 1.6 1 0 0 1 1 1 0 Serglycin Phosphorylase PF00343.20 OWF50424.1 - 0 1151.4 0.0 0 1151.1 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF2391 PF09622.10 OWF50424.1 - 0.051 12.9 0.1 6.2 6.1 0.0 2.8 3 0 0 3 3 3 0 Putative integral membrane protein (DUF2391) Neur_chan_LBD PF02931.23 OWF50426.1 - 4.3e-17 62.3 0.2 5.9e-17 61.8 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50426.1 - 1.6e-11 44.8 7.6 1.6e-11 44.8 7.6 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region GWT1 PF06423.12 OWF50426.1 - 0.86 9.7 4.2 1 9.4 3.0 1.8 1 1 0 1 1 1 0 GWT1 DUF2258 PF10015.9 OWF50427.1 - 0.07 13.3 0.2 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) E1_DerP2_DerF2 PF02221.15 OWF50428.1 - 3.3e-23 82.6 0.3 3.7e-23 82.4 0.3 1.0 1 0 0 1 1 1 1 ML domain BLM10_mid PF16507.5 OWF50429.1 - 1.5e-102 344.0 3.3 1.2e-100 337.7 3.3 2.7 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OWF50429.1 - 3.1e-36 123.2 0.0 3.1e-35 119.9 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 OWF50429.1 - 0.0073 16.5 0.1 2 8.9 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 OWF50429.1 - 0.035 14.6 0.0 6.1 7.5 0.0 4.1 3 0 0 3 3 3 0 HEAT-like repeat UME PF08064.13 OWF50429.1 - 0.11 12.4 0.0 2.3 8.2 0.2 3.3 3 0 0 3 3 3 0 UME (NUC010) domain Whirly PF08536.11 OWF50430.1 - 0.091 12.6 53.7 40 4.0 1.3 11.3 1 1 12 14 14 14 0 Whirly transcription factor DEAD PF00270.29 OWF50431.1 - 2.1e-51 174.2 0.0 6.4e-51 172.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF50431.1 - 4.2e-25 88.3 0.0 3.7e-24 85.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF50431.1 - 3.4e-05 23.9 0.0 0.00027 21.0 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CdAMP_rec PF06153.11 OWF50431.1 - 0.0095 16.1 0.7 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 Cyclic-di-AMP receptor DUF3928 PF13065.6 OWF50431.1 - 0.13 13.0 0.1 0.39 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) Gar1 PF04410.14 OWF50432.1 - 6.5e-32 110.4 1.8 8.5e-32 110.1 1.8 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Chibby PF14645.6 OWF50433.1 - 1.7e-41 141.3 0.3 1.9e-41 141.1 0.3 1.0 1 0 0 1 1 1 1 Chibby family TMC PF07810.13 OWF50434.1 - 3.7e-39 133.7 1.4 3.7e-39 133.7 1.4 2.4 2 0 0 2 2 2 1 TMC domain Ank_2 PF12796.7 OWF50435.1 - 7.6e-31 106.6 2.0 3.2e-12 46.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50435.1 - 1.9e-17 63.4 0.0 1.4e-07 32.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF50435.1 - 5.1e-16 58.5 0.6 1.8e-06 28.1 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) PLAT PF01477.23 OWF50435.1 - 1.7e-15 57.6 0.0 5.3e-15 56.0 0.0 2.0 1 0 0 1 1 1 1 PLAT/LH2 domain Ank PF00023.30 OWF50435.1 - 5.6e-15 55.0 1.0 0.00041 20.7 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 OWF50435.1 - 5.5e-14 50.9 1.3 0.019 15.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Cupin_8 PF13621.6 OWF50436.1 - 1.2e-42 146.4 0.9 1.6e-42 146.0 0.9 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OWF50436.1 - 1.1e-10 41.5 0.3 2.1e-10 40.6 0.2 1.6 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OWF50436.1 - 0.0035 17.7 0.5 0.038 14.4 0.1 2.8 1 1 1 2 2 2 1 JmjC domain, hydroxylase Med14 PF08638.11 OWF50436.1 - 0.062 12.7 0.2 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit MED14 Peptidase_M24 PF00557.24 OWF50438.1 - 4e-23 82.2 0.2 4.7e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 LMBR1 PF04791.16 OWF50439.1 - 1.3e-87 294.9 24.2 1.1e-58 199.4 13.5 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF3671 PF12420.8 OWF50439.1 - 0.0026 17.8 16.1 0.2 11.8 0.1 4.1 4 0 0 4 4 4 3 Protein of unknown function DUF575 PF04746.12 OWF50439.1 - 0.074 13.3 1.2 5.9 7.2 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF575) CrgA PF06781.12 OWF50439.1 - 0.24 11.5 3.8 2.6 8.1 1.3 3.2 3 0 0 3 3 3 0 Cell division protein CrgA SH PF01445.17 OWF50439.1 - 0.29 11.1 3.8 0.77 9.8 0.0 3.0 2 0 0 2 2 2 0 Viral small hydrophobic protein TMEM154 PF15102.6 OWF50439.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.1 4 1 0 4 4 4 0 TMEM154 protein family FAD_binding_1 PF00667.20 OWF50440.1 - 3.6e-41 141.2 0.0 5.3e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OWF50440.1 - 8.5e-35 120.1 0.0 1.9e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OWF50440.1 - 3.7e-16 59.7 0.0 1.2e-15 58.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OWF50440.1 - 0.00017 21.8 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 OWF50440.1 - 0.11 12.2 0.1 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain IQ PF00612.27 OWF50441.1 - 1.4e-10 39.9 13.2 0.00059 19.4 2.5 4.1 3 0 0 3 3 3 3 IQ calmodulin-binding motif TetR_C_13 PF16925.5 OWF50441.1 - 0.078 12.9 5.0 0.12 12.3 0.1 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Hus1 PF04005.12 OWF50442.1 - 1.3e-82 277.2 1.2 1.5e-82 277.0 1.2 1.0 1 0 0 1 1 1 1 Hus1-like protein AIG1 PF04548.16 OWF50443.1 - 5.7e-30 104.2 0.1 9.3e-30 103.5 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF50443.1 - 4.9e-06 26.6 0.8 8.9e-06 25.8 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OWF50443.1 - 0.0069 16.5 3.8 3.2 7.8 0.0 3.2 3 0 0 3 3 3 2 Dynamin family Sigma54_activat PF00158.26 OWF50443.1 - 0.016 14.9 0.4 0.049 13.3 0.1 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 OWF50443.1 - 0.042 13.4 0.1 0.099 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region THDPS_N PF14790.6 OWF50443.1 - 0.051 13.4 3.7 0.028 14.2 1.5 1.6 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal RNA_helicase PF00910.22 OWF50443.1 - 0.078 13.4 1.2 1.7 9.0 0.0 2.9 3 0 0 3 3 3 0 RNA helicase RsgA_GTPase PF03193.16 OWF50443.1 - 0.1 12.5 0.7 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 OWF50443.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.4 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 OWF50443.1 - 0.15 11.4 3.0 1.8 7.9 0.2 3.1 2 1 2 4 4 4 0 FtsK/SpoIIIE family DUF4337 PF14235.6 OWF50443.1 - 4.7 7.3 6.6 7.6 6.6 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ACBP PF00887.19 OWF50444.1 - 1.2e-24 86.3 0.2 2.1e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 OWF50444.1 - 4.3e-18 65.1 0.3 4.1e-11 42.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF50444.1 - 6.8e-13 48.4 0.6 8.4e-05 22.8 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OWF50444.1 - 9.5e-13 48.6 0.1 1.7e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF50444.1 - 9.7e-12 44.0 0.1 8.9e-06 25.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OWF50444.1 - 5.6e-11 42.8 0.2 3.3e-08 33.9 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Bactofilin PF04519.13 OWF50445.1 - 0.00026 21.2 0.0 0.29 11.5 0.0 2.3 1 1 1 2 2 2 2 Polymer-forming cytoskeletal HtaA PF04213.13 OWF50445.1 - 0.0094 16.4 1.5 2.7 8.4 0.1 2.1 1 1 1 2 2 2 2 Htaa I-set PF07679.16 OWF50445.1 - 0.025 14.7 5.4 3.2 7.9 0.2 4.1 3 2 1 4 4 4 0 Immunoglobulin I-set domain GLEYA PF10528.9 OWF50445.1 - 0.029 14.8 5.2 5 7.6 0.2 3.5 3 1 0 3 3 3 0 GLEYA domain DUF1943 PF09172.11 OWF50445.1 - 0.06 12.6 0.1 0.26 10.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) DUF481 PF04338.12 OWF50445.1 - 0.14 12.1 0.2 11 5.9 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function, DUF481 Prok-RING_2 PF14445.6 OWF50445.1 - 0.21 11.8 8.4 5.2 7.3 0.3 3.8 2 1 2 4 4 4 0 Prokaryotic RING finger family 2 Cas6b_C PF17262.2 OWF50445.1 - 0.31 11.1 6.7 20 5.3 0.3 3.2 1 1 1 3 3 3 0 Cas6b C-terminal domain Neocarzinostat PF00960.18 OWF50445.1 - 0.39 10.7 9.5 2.6 8.1 0.5 3.3 1 1 2 3 3 3 0 Neocarzinostatin family R_equi_Vir PF05526.11 OWF50445.1 - 0.54 10.1 6.0 11 5.8 0.1 3.2 1 1 1 3 3 3 0 Rhodococcus equi virulence-associated protein MG3 PF17791.1 OWF50445.1 - 1.8 8.9 10.0 19 5.6 10.0 2.4 1 1 0 1 1 1 0 Macroglobulin domain MG3 DUF4893 PF16233.5 OWF50445.1 - 5 6.7 10.8 1.5 8.4 0.4 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4893) Hex_IIIa PF02455.16 OWF50445.1 - 5.5 5.6 7.2 8.6 5.0 1.8 2.3 1 1 1 2 2 2 0 Hexon-associated protein (IIIa) 7tm_1 PF00001.21 OWF50446.1 - 1.9e-20 73.3 6.7 4e-20 72.3 6.8 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF50446.1 - 0.011 15.5 6.4 0.054 13.2 5.1 2.1 2 0 0 2 2 2 0 Olfactory receptor Croc_4 PF17691.1 OWF50446.1 - 0.058 13.4 0.1 0.098 12.7 0.1 1.2 1 0 0 1 1 1 0 Contingent replication of cDNA 4 FAST_1 PF06743.15 OWF50446.1 - 0.18 11.7 1.1 0.97 9.4 0.2 2.2 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 1 Flu_M2 PF00599.17 OWF50447.1 - 4.6 7.4 5.6 1.7 8.8 0.8 2.2 1 1 1 2 2 2 0 Influenza Matrix protein (M2) HLH PF00010.26 OWF50448.1 - 2.6e-18 65.7 0.3 4e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 OWF50449.1 - 1.3e-19 69.9 0.1 1.3e-19 69.9 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Drf_FH3 PF06367.16 OWF50449.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain HLH PF00010.26 OWF50452.1 - 2.6e-18 65.7 0.6 4.3e-18 65.0 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Amidase_3 PF01520.18 OWF50452.1 - 0.14 12.2 0.2 6.5 6.8 0.0 2.1 1 1 1 2 2 2 0 N-acetylmuramoyl-L-alanine amidase Glycophorin_A PF01102.18 OWF50453.1 - 0.0021 18.3 0.1 0.0035 17.6 0.1 1.3 1 0 0 1 1 1 1 Glycophorin A DUF4690 PF15756.5 OWF50453.1 - 0.0048 17.5 0.1 0.0086 16.7 0.1 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage VSP PF03302.13 OWF50453.1 - 0.0052 15.7 0.1 0.0052 15.7 0.1 2.0 2 1 0 2 2 2 1 Giardia variant-specific surface protein pP_pnuc_2 PF18166.1 OWF50453.1 - 0.023 14.8 0.0 0.065 13.3 0.0 1.7 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease CD99L2 PF12301.8 OWF50453.1 - 0.028 14.7 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Podoplanin PF05808.11 OWF50453.1 - 0.05 13.7 0.3 0.074 13.2 0.3 1.2 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.6 OWF50453.1 - 0.059 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family SecE PF00584.20 OWF50453.1 - 0.095 12.6 2.5 0.16 11.9 2.5 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex FAM24 PF15193.6 OWF50454.1 - 1.6e-07 32.0 3.5 27 5.6 0.0 7.4 4 1 3 8 8 8 2 FAM24 family Metallothio_2 PF01439.18 OWF50454.1 - 0.023 15.6 5.2 92 4.0 0.1 7.0 5 3 5 10 10 10 0 Metallothionein RRM_9 PF18444.1 OWF50454.1 - 0.13 12.1 2.0 55 3.7 0.1 4.1 3 2 1 5 5 5 0 RNA recognition motif MRPL52 PF18699.1 OWF50454.1 - 0.19 11.9 10.8 54 4.1 0.0 6.5 6 3 3 9 9 9 0 Mitoribosomal protein mL52 TGF_beta PF00019.20 OWF50455.1 - 0.0073 17.3 0.0 0.019 15.9 0.0 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain FYDLN_acid PF09538.10 OWF50456.1 - 0.1 13.3 1.7 0.52 11.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pentapeptide_4 PF13599.6 OWF50457.1 - 1.4e-06 28.3 32.1 0.26 11.5 3.4 5.4 1 1 4 5 5 5 5 Pentapeptide repeats (9 copies) Cytochrom_B559 PF00283.19 OWF50457.1 - 0.0032 16.9 15.1 8.9 5.9 0.1 8.4 4 2 3 7 7 7 4 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits EF-hand_7 PF13499.6 OWF50458.1 - 7.5e-09 35.9 1.5 2e-07 31.3 1.7 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF50458.1 - 3.7e-08 32.4 2.2 0.00016 21.0 0.8 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF50458.1 - 3.8e-08 32.6 0.4 0.0011 18.7 0.7 3.2 3 0 0 3 3 3 2 EF-hand domain IBP39 PF11422.8 OWF50458.1 - 0.00021 21.1 0.2 0.00026 20.8 0.2 1.3 1 0 0 1 1 1 1 Initiator binding protein 39 kDa EF-hand_5 PF13202.6 OWF50458.1 - 0.00022 20.5 3.6 0.12 11.9 0.2 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 OWF50458.1 - 0.0023 18.2 0.7 0.077 13.3 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 OWF50458.1 - 0.013 15.4 3.4 0.042 13.7 1.0 2.7 2 1 0 2 2 2 0 EF-hand domain pair zf-UBR PF02207.20 OWF50459.1 - 6.4e-18 64.7 8.7 6.4e-18 64.7 8.7 3.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Aminotran_1_2 PF00155.21 OWF50460.1 - 1.7e-28 99.9 0.0 2e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OWF50460.1 - 4.3e-08 32.4 0.0 7.1e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 OWF50461.1 - 7.2e-35 120.8 0.0 8.7e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OWF50461.1 - 1.2e-10 40.8 0.0 1.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ABC_membrane PF00664.23 OWF50462.1 - 4.8e-134 446.2 24.0 4.6e-72 243.0 6.7 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF50462.1 - 4.2e-76 254.0 0.2 1e-36 126.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF50462.1 - 1.1e-17 64.3 0.5 2.9e-08 33.4 0.0 3.7 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OWF50462.1 - 3.4e-09 36.0 0.1 0.00011 21.2 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 OWF50462.1 - 7.6e-09 36.2 2.2 0.0044 17.4 0.6 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OWF50462.1 - 3e-08 34.0 1.0 0.012 15.9 0.1 3.2 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OWF50462.1 - 4e-07 30.1 0.0 0.018 14.9 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase Zeta_toxin PF06414.12 OWF50462.1 - 6.8e-07 28.8 0.1 0.034 13.4 0.0 3.4 3 0 0 3 3 3 2 Zeta toxin Rad17 PF03215.15 OWF50462.1 - 1.3e-06 28.5 0.1 0.077 12.9 0.0 2.7 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_5 PF07728.14 OWF50462.1 - 5.3e-06 26.5 0.1 0.29 11.1 0.0 3.9 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OWF50462.1 - 6.4e-06 25.6 0.0 0.073 12.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_15 PF13175.6 OWF50462.1 - 1.3e-05 25.1 5.2 0.05 13.3 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 OWF50462.1 - 1.9e-05 25.1 2.6 0.85 10.1 0.4 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OWF50462.1 - 2.1e-05 24.2 0.2 0.13 12.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 OWF50462.1 - 2.1e-05 24.7 0.1 0.63 10.1 0.0 3.7 4 0 0 4 4 3 2 Helicase HerA, central domain AAA_30 PF13604.6 OWF50462.1 - 3.1e-05 23.8 2.6 0.24 11.1 0.2 3.5 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OWF50462.1 - 3.2e-05 23.5 0.0 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 OWF50462.1 - 6e-05 23.2 7.4 0.17 12.1 0.4 4.4 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 OWF50462.1 - 0.0001 22.0 0.4 0.26 10.9 0.1 2.9 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 OWF50462.1 - 0.00035 20.4 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OWF50462.1 - 0.00037 19.8 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_18 PF13238.6 OWF50462.1 - 0.00046 20.7 0.0 1.3 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain tRNA_lig_kinase PF08303.11 OWF50462.1 - 0.00075 19.6 0.1 0.58 10.2 0.0 2.6 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_28 PF13521.6 OWF50462.1 - 0.001 19.4 0.4 2.2 8.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_21 PF13304.6 OWF50462.1 - 0.0011 18.9 0.0 3.7 7.3 0.0 4.1 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 OWF50462.1 - 0.0014 18.4 0.0 0.9 9.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 OWF50462.1 - 0.0025 18.2 0.0 3 8.3 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.6 OWF50462.1 - 0.0087 15.6 0.2 1.2 8.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OWF50462.1 - 0.0089 15.8 0.5 22 4.7 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_33 PF13671.6 OWF50462.1 - 0.012 15.7 0.0 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain FUSC PF04632.12 OWF50462.1 - 0.013 14.1 0.1 0.028 13.0 0.1 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_14 PF13173.6 OWF50462.1 - 0.016 15.3 0.0 12 6.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 OWF50462.1 - 0.018 14.9 0.1 4.7 7.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 OWF50462.1 - 0.019 14.1 0.9 7.8 5.6 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain APS_kinase PF01583.20 OWF50462.1 - 0.025 14.5 0.1 9.9 6.0 0.0 2.9 3 0 0 3 3 2 0 Adenylylsulphate kinase TniB PF05621.11 OWF50462.1 - 0.033 13.6 0.0 22 4.4 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein DUF2207 PF09972.9 OWF50462.1 - 0.042 12.6 0.1 0.042 12.6 0.1 3.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Sigma54_activat PF00158.26 OWF50462.1 - 0.049 13.3 0.0 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain YL1_C PF08265.11 OWF50463.1 - 5.2e-12 45.3 0.1 1.1e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Man-6-P_recep PF02157.15 OWF50464.1 - 1.5e-22 80.0 0.1 2e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OWF50464.1 - 6.2e-17 62.3 1.5 9.9e-17 61.7 1.5 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OWF50464.1 - 8.3e-06 25.9 0.2 0.092 12.8 0.2 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Ion_trans PF00520.31 OWF50464.1 - 0.03 13.6 0.2 0.048 12.9 0.2 1.3 1 0 0 1 1 1 0 Ion transport protein SP_C-Propep PF08999.10 OWF50464.1 - 0.032 14.0 0.1 0.083 12.7 0.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Glyco_transf_11 PF01531.16 OWF50465.1 - 8.2e-47 159.8 3.6 1e-46 159.6 3.6 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 ATG27 PF09451.10 OWF50466.1 - 2.2e-16 60.5 0.8 3.1e-16 60.0 0.8 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF50466.1 - 6.7e-14 51.6 0.0 8.6e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 OWF50466.1 - 2.6e-08 34.0 0.9 0.00085 19.4 0.0 2.1 1 1 1 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat RHS_repeat PF05593.14 OWF50466.1 - 0.18 12.4 3.4 0.79 10.3 1.2 2.6 2 0 0 2 2 2 0 RHS Repeat Aldo_ket_red PF00248.21 OWF50467.1 - 5.2e-53 180.2 0.0 7e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 OWF50467.1 - 0.0025 18.1 0.2 0.86 9.9 0.0 2.7 2 1 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain PdxJ PF03740.13 OWF50467.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ CpxA_peri PF16527.5 OWF50467.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain VWC PF00093.18 OWF50468.1 - 3.4e-11 43.3 35.4 6.4e-06 26.4 7.7 4.0 2 1 2 4 4 4 2 von Willebrand factor type C domain zf_CCCH_4 PF18345.1 OWF50468.1 - 0.22 11.6 9.1 1.6 8.9 2.0 4.4 3 0 0 3 3 3 0 Zinc finger domain Reg_prop PF07494.11 OWF50469.1 - 0.024 14.8 2.6 37 5.0 0.0 5.1 6 0 0 6 6 6 0 Two component regulator propeller NHL PF01436.21 OWF50469.1 - 0.054 13.6 6.6 0.39 10.8 0.0 4.6 4 0 0 4 4 4 0 NHL repeat DUF1664 PF07889.12 OWF50469.1 - 0.25 11.4 2.3 0.48 10.5 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Dynactin_p22 PF07426.11 OWF50469.1 - 0.56 10.0 4.8 11 5.8 1.2 2.0 1 1 1 2 2 2 0 Dynactin subunit p22 SnAPC_2_like PF11035.8 OWF50470.1 - 5.1e-09 36.7 0.6 5.1e-09 36.7 0.6 3.8 3 1 1 4 4 4 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF4755 PF15947.5 OWF50470.1 - 0.13 12.3 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4755) Glycogen_syn PF05693.13 OWF50470.1 - 0.53 8.8 1.5 0.93 8.0 1.5 1.3 1 0 0 1 1 1 0 Glycogen synthase Pkinase PF00069.25 OWF50471.1 - 3.4e-67 226.6 0.0 4.1e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF50471.1 - 1.8e-25 89.7 0.0 2.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF50471.1 - 3.1e-07 30.0 0.0 6.3e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 OWF50471.1 - 5.7e-05 23.1 0.0 0.025 14.5 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OWF50471.1 - 0.0038 16.6 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 OWF50471.1 - 0.029 13.2 0.6 0.051 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OWF50471.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 OWF50471.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 ABC1 family LRR_8 PF13855.6 OWF50472.1 - 1.2e-30 105.0 31.3 1.8e-08 34.0 10.3 5.3 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OWF50472.1 - 7.9e-19 67.5 39.4 1.4e-06 28.6 1.0 6.9 4 1 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF50472.1 - 5.3e-07 29.3 33.8 1 10.2 0.0 9.1 8 2 0 8 8 8 5 Leucine Rich Repeat LRR_5 PF13306.6 OWF50472.1 - 0.047 13.7 3.3 0.23 11.4 1.7 2.4 1 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Pex19 PF04614.12 OWF50473.1 - 6.6e-50 170.2 22.0 6.6e-50 170.2 22.0 1.5 2 0 0 2 2 2 1 Pex19 protein family VPS28 PF03997.12 OWF50473.1 - 0.0079 15.9 3.7 0.071 12.8 3.0 2.4 1 1 0 1 1 1 1 VPS28 protein DUF4487 PF14868.6 OWF50473.1 - 0.0093 14.8 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4487) AAA_13 PF13166.6 OWF50473.1 - 0.037 12.7 3.7 0.064 11.9 3.7 1.3 1 0 0 1 1 1 0 AAA domain ZapD PF07072.11 OWF50473.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.2 2 1 0 2 2 2 0 Cell division protein Plasmid_RAQPRD PF09686.10 OWF50473.1 - 0.15 12.2 3.7 0.25 11.6 0.6 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MetOD1 PF18546.1 OWF50473.1 - 0.33 10.9 5.2 0.59 10.1 0.2 2.2 2 0 0 2 2 2 0 Metanogen output domain 1 Lant_dehydr_C PF14028.6 OWF50473.1 - 0.41 10.1 0.8 1.4 8.4 0.1 1.8 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term PHA_synth_III_E PF09712.10 OWF50473.1 - 0.42 9.7 11.3 0.94 8.5 11.3 1.5 1 1 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) KinB_sensor PF16767.5 OWF50473.1 - 0.61 10.6 5.5 0.51 10.8 0.5 2.7 2 2 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF1664 PF07889.12 OWF50473.1 - 0.67 10.0 3.8 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 OWF50473.1 - 0.88 10.1 10.7 0.061 13.8 2.3 2.8 3 1 1 4 4 4 0 Spectrin repeat ING PF12998.7 OWF50473.1 - 3.1 8.4 8.6 21 5.8 5.4 3.1 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Ets PF00178.22 OWF50474.1 - 8.1e-33 112.7 0.5 1.6e-32 111.8 0.5 1.5 1 0 0 1 1 1 1 Ets-domain NPM1-C PF16276.5 OWF50474.1 - 0.023 14.7 0.2 6.1 6.9 0.1 2.8 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain Collagen PF01391.18 OWF50475.1 - 6.4e-07 29.0 0.2 0.00018 21.2 0.2 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Cuticle_1 PF08140.11 OWF50475.1 - 0.091 12.8 31.4 7.5 6.7 0.9 6.8 1 1 6 7 7 7 0 Crustacean cuticle protein repeat Drf_FH1 PF06346.12 OWF50475.1 - 0.14 11.8 3.7 0.17 11.6 3.7 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 SPASM PF13186.6 OWF50475.1 - 1.1 9.8 6.7 1.1e+02 3.4 0.6 4.8 1 1 1 2 2 2 0 Iron-sulfur cluster-binding domain Phi_1 PF04674.12 OWF50475.1 - 4.5 6.5 9.6 24 4.1 0.4 3.5 1 1 3 4 4 4 0 Phosphate-induced protein 1 conserved region Ets PF00178.22 OWF50477.1 - 5e-35 119.8 0.3 8.5e-35 119.1 0.3 1.4 1 0 0 1 1 1 1 Ets-domain IgGFc_binding PF17517.2 OWF50478.1 - 8.2e-46 156.6 9.3 8.2e-46 156.6 9.3 1.4 2 0 0 2 2 2 1 IgGFc binding protein MF_alpha_N PF05436.11 OWF50479.1 - 0.052 13.4 0.1 0.059 13.3 0.1 1.0 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Lectin_C PF00059.21 OWF50480.1 - 5.2e-14 52.9 0.0 6.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 OWF50481.1 - 0.0014 18.9 1.0 0.013 15.9 0.2 2.5 2 1 0 2 2 2 1 CUB domain Lipase_GDSL_2 PF13472.6 OWF50482.1 - 0.014 15.8 0.0 0.014 15.8 0.0 1.0 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Hamartin PF04388.12 OWF50483.1 - 0.26 9.9 11.0 0.3 9.7 11.0 1.1 1 0 0 1 1 1 0 Hamartin protein Drf_FH1 PF06346.12 OWF50483.1 - 0.41 10.4 6.5 0.53 10.0 6.5 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 CUB PF00431.20 OWF50484.1 - 4.9e-32 110.5 7.5 1.7e-10 41.2 0.1 5.4 4 2 0 4 4 4 4 CUB domain Chordopox_A13L PF05961.11 OWF50484.1 - 0.0015 18.7 1.2 0.0031 17.7 0.3 2.0 2 0 0 2 2 2 1 Chordopoxvirus A13L protein Cadherin_C_2 PF16492.5 OWF50484.1 - 0.0017 19.0 0.0 0.0055 17.4 0.0 1.9 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal LTD PF00932.19 OWF50484.1 - 0.0022 18.3 0.4 2.9 8.3 0.0 2.8 2 1 0 2 2 2 2 Lamin Tail Domain EphA2_TM PF14575.6 OWF50484.1 - 0.0044 17.9 0.4 0.011 16.6 0.4 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OWF50484.1 - 0.0072 16.6 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 Orf78 (ac78) Peptidase_C97 PF05903.14 OWF50484.1 - 0.0084 15.9 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 2 PPPDE putative peptidase domain TMEM154 PF15102.6 OWF50484.1 - 0.023 14.6 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family Ig_mannosidase PF17753.1 OWF50484.1 - 0.023 14.4 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Ig-fold domain Lysyl_oxidase PF01186.17 OWF50484.1 - 0.22 11.2 3.5 9 5.9 0.1 3.2 3 0 0 3 3 3 0 Lysyl oxidase ECH_1 PF00378.20 OWF50485.1 - 8.5e-46 156.3 0.2 1.5e-45 155.4 0.2 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF50485.1 - 9.3e-27 94.4 0.1 4.1e-25 89.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 OWF50486.1 - 1.3e-35 122.7 0.0 2.1e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50486.1 - 3.8e-22 79.0 0.0 6.4e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OWF50486.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OWF50486.1 - 1.6e-07 31.4 0.0 2.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OWF50486.1 - 0.0034 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 OWF50486.1 - 0.0064 16.7 0.1 0.018 15.3 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 OWF50486.1 - 0.023 14.8 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.6 OWF50486.1 - 0.039 13.9 0.0 0.074 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Plasmodium_HRP PF05403.11 OWF50487.1 - 0.00034 20.5 60.2 0.16 11.8 37.1 2.3 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) DUF1816 PF08846.10 OWF50487.1 - 0.00058 19.8 0.1 28 4.8 0.0 4.7 2 2 2 4 4 4 3 Domain of unknown function (DUF1816) Plasmodium_HRP PF05403.11 OWF50488.1 - 3e-05 23.9 81.1 0.028 14.2 23.2 3.6 1 1 3 4 4 4 4 Plasmodium histidine-rich protein (HRPII/III) DUF4690 PF15756.5 OWF50488.1 - 0.0007 20.1 0.7 27 5.5 0.0 4.6 1 1 4 6 6 6 1 Small Novel Rich in Cartilage FimH_man-bind PF09160.10 OWF50488.1 - 0.047 13.4 4.2 1.6 8.4 0.1 3.8 1 1 3 4 4 4 0 FimH, mannose binding DUF3911 PF13050.6 OWF50488.1 - 5.9 7.1 6.9 48 4.2 0.2 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF3911) Plasmodium_HRP PF05403.11 OWF50489.1 - 5.8e-07 29.5 48.8 5.6e-05 23.1 23.6 2.0 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) NFACT-R_1 PF05670.13 OWF50490.1 - 9.2e-34 116.4 2.0 1.8e-33 115.4 0.0 2.6 3 0 0 3 3 3 1 NFACT protein RNA binding domain FbpA PF05833.11 OWF50490.1 - 1.6e-30 106.3 11.3 1.6e-30 106.3 11.3 3.4 2 2 2 4 4 4 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 OWF50490.1 - 1.4e-09 37.8 0.0 1.4e-09 37.8 0.0 4.3 4 1 0 4 4 4 1 NFACT protein C-terminal domain Glyco_hydro_38N PF01074.22 OWF50491.1 - 1.3e-84 284.0 4.4 2e-84 283.4 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF50491.1 - 1.5e-27 97.1 0.0 4.1e-27 95.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF50491.1 - 3.9e-23 81.4 0.1 9.8e-23 80.1 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain BRO1 PF03097.18 OWF50492.1 - 2e-39 135.5 0.9 2.6e-39 135.1 0.9 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF4423 PF14394.6 OWF50492.1 - 0.098 12.4 0.5 0.35 10.6 0.1 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4423) TFIIA PF03153.13 OWF50493.1 - 3.2 7.7 32.2 0.049 13.6 24.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 OWF50494.1 - 2.5e-37 128.3 0.0 3.4e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50494.1 - 1.2e-28 100.2 0.0 1.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF50494.1 - 4.7e-09 36.4 0.0 7.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF50494.1 - 3.9e-06 26.5 0.0 5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OWF50494.1 - 0.0032 17.0 0.1 0.0083 15.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HMG_box PF00505.19 OWF50494.1 - 0.19 12.2 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box adh_short PF00106.25 OWF50495.1 - 1.1e-124 413.3 0.0 2.6e-41 141.2 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50495.1 - 4.8e-94 314.3 0.0 8.2e-30 104.1 0.0 3.1 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF50495.1 - 3.8e-26 92.1 0.0 6.3e-08 32.7 0.0 3.3 3 0 0 3 3 3 3 KR domain DUF1776 PF08643.10 OWF50495.1 - 7.3e-22 78.1 0.0 1.5e-05 24.5 0.0 4.9 3 3 0 3 3 3 3 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OWF50495.1 - 8.8e-15 54.8 0.2 0.00038 20.0 0.0 3.7 3 1 0 3 3 3 3 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OWF50495.1 - 1.2e-11 44.8 0.1 0.014 15.3 0.0 3.4 3 0 0 3 3 3 3 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OWF50495.1 - 8.5e-09 35.2 0.1 0.03 13.7 0.0 3.4 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase LEM PF03020.15 OWF50495.1 - 5.7e-07 29.0 0.0 1.6 8.3 0.0 3.6 3 0 0 3 3 3 3 LEM domain Peptidase_S49 PF01343.18 OWF50495.1 - 1.5e-06 28.2 1.2 0.35 10.8 0.0 3.5 3 0 0 3 3 3 2 Peptidase family S49 Peptidase_S13 PF02113.15 OWF50495.1 - 0.00034 19.5 0.0 2.4 6.8 0.0 3.2 3 0 0 3 3 3 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family AP_endonuc_2 PF01261.24 OWF50495.1 - 0.0017 17.8 0.0 6.2 6.2 0.0 3.8 4 0 0 4 4 4 1 Xylose isomerase-like TIM barrel YpzI PF14140.6 OWF50495.1 - 0.0038 16.9 0.0 5.1 6.9 0.0 2.7 2 0 0 2 2 2 2 YpzI-like protein Gamma_PGA_hydro PF05908.11 OWF50495.1 - 0.0048 16.3 0.2 1.6 8.1 0.0 2.9 3 0 0 3 3 3 1 Poly-gamma-glutamate hydrolase Eno-Rase_NADH_b PF12242.8 OWF50495.1 - 0.0076 16.0 0.0 5.5 6.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrbH PF07283.11 OWF50495.1 - 0.015 15.4 0.1 4.3 7.5 0.0 2.9 3 0 0 3 3 3 0 Conjugal transfer protein TrbH Phi-29_GP3 PF05435.11 OWF50495.1 - 0.016 14.7 0.1 22 4.4 0.1 3.2 3 0 0 3 3 3 0 Phi-29 DNA terminal protein GP3 Sulphotransf PF09037.10 OWF50495.1 - 0.068 12.7 0.1 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Stf0 sulphotransferase QRPTase_C PF01729.19 OWF50495.1 - 0.076 12.8 0.4 3.8 7.3 0.1 3.0 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Mst1_SARAH PF11629.8 OWF50495.1 - 0.15 12.2 0.8 29 4.8 0.1 2.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 GreA_GreB_N PF03449.15 OWF50495.1 - 0.24 11.6 1.7 17 5.7 0.1 3.3 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal zf-C2HC_2 PF13913.6 OWF50496.1 - 8.4e-16 57.4 13.4 1.2e-08 34.6 1.2 3.0 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DUF2318 PF10080.9 OWF50496.1 - 0.00019 21.5 1.4 0.0011 19.1 0.3 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2318) HypA PF01155.19 OWF50496.1 - 0.019 15.0 3.5 0.25 11.4 0.2 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 OWF50496.1 - 0.031 14.2 5.8 1.2 9.1 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_7 PF02591.15 OWF50496.1 - 0.15 12.3 3.3 6 7.2 0.3 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-C2H2_4 PF13894.6 OWF50496.1 - 0.21 12.5 6.9 3.9 8.6 1.1 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF50496.1 - 0.29 11.6 1.5 23 5.6 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf_UBZ PF18439.1 OWF50496.1 - 0.39 10.4 2.0 20 4.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-CHCC PF10276.9 OWF50496.1 - 0.63 10.1 2.7 14 5.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger domain Sgf11 PF08209.11 OWF50496.1 - 0.65 9.6 6.4 3.2 7.4 0.4 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2 PF00096.26 OWF50496.1 - 1.8 9.2 6.4 11 6.7 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type ADK_lid PF05191.14 OWF50496.1 - 3.9 7.6 6.1 14 5.8 0.6 2.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid MutL_C PF08676.11 OWF50497.1 - 3.1e-15 56.2 0.1 1.3e-14 54.2 0.1 2.0 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OWF50497.1 - 7.5e-11 41.8 0.0 2e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OWF50497.1 - 1.2e-08 34.8 0.0 7.5e-08 32.3 0.0 2.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OWF50497.1 - 8.2e-06 26.3 0.0 2.7e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_22 PF13383.6 OWF50498.1 - 7.4e-15 55.2 0.1 1.1e-14 54.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF50498.1 - 9.3e-05 22.5 0.1 0.0003 20.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase FkbM domain 7tm_1 PF00001.21 OWF50499.1 - 1.4e-25 90.1 13.9 1.8e-25 89.8 13.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Claudin_2 PF13903.6 OWF50499.1 - 0.0039 17.0 9.3 0.014 15.1 1.7 2.8 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction PLAC8 PF04749.17 OWF50499.1 - 1.6 9.8 6.2 1.6 9.8 0.1 2.8 2 1 0 2 2 2 0 PLAC8 family BIR PF00653.21 OWF50500.1 - 2.2e-09 37.8 0.2 2.2e-09 37.8 0.2 1.7 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Trypsin_2 PF13365.6 OWF50502.1 - 1.5e-10 42.2 0.0 3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF50502.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Trypsin p450 PF00067.22 OWF50503.1 - 2.4e-72 244.2 0.0 2.9e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5624 PF18538.1 OWF50504.1 - 0.051 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) CD225 PF04505.12 OWF50505.1 - 2.3e-13 50.1 0.1 3.3e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 OWF50505.1 - 0.018 14.8 1.5 0.035 13.9 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) DUF4064 PF13273.6 OWF50505.1 - 0.043 14.1 0.5 0.29 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Orf78 PF06024.12 OWF50505.1 - 0.053 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) SOGA PF11365.8 OWF50507.1 - 0.032 15.3 0.9 0.059 14.5 0.9 1.5 1 0 0 1 1 1 0 Protein SOGA Innexin PF00876.18 OWF50508.1 - 1.2e-125 419.4 19.9 1.4e-125 419.2 19.9 1.0 1 0 0 1 1 1 1 Innexin Phage_int_SAM_5 PF13102.6 OWF50508.1 - 0.095 13.0 1.1 0.36 11.2 0.3 2.3 2 1 1 3 3 3 0 Phage integrase SAM-like domain EamA PF00892.20 OWF50510.1 - 0.035 14.3 6.7 1.2 9.3 0.3 2.1 1 1 1 2 2 2 0 EamA-like transporter family KRAP_IP3R_bind PF14722.6 OWF50510.1 - 0.14 11.9 0.7 95 2.7 0.0 3.5 4 0 0 4 4 4 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain SUV3_C PF12513.8 OWF50510.1 - 0.14 12.1 7.0 0.23 11.4 0.2 3.9 4 1 1 5 5 5 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF411 PF04214.13 OWF50510.1 - 0.62 10.0 3.5 4.5 7.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF ASFV_J13L PF05568.11 OWF50511.1 - 0.87 9.3 25.5 30 4.3 0.4 7.8 1 1 7 9 9 9 0 African swine fever virus J13L protein ASFV_J13L PF05568.11 OWF50513.1 - 1.5 8.6 3.7 17 5.1 0.1 3.1 1 1 3 4 4 4 0 African swine fever virus J13L protein Neuralized PF07177.12 OWF50514.1 - 2e-255 836.1 5.3 1.4e-44 151.7 0.1 6.2 6 0 0 6 6 6 6 Neuralized SPRY PF00622.28 OWF50514.1 - 4.4e-20 72.0 2.4 0.00091 19.3 0.0 6.4 6 0 0 6 6 6 6 SPRY domain Laminin_G_3 PF13385.6 OWF50514.1 - 0.0099 16.0 1.4 21 5.2 0.1 4.4 4 0 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily ADH_N PF08240.12 OWF50514.1 - 0.036 13.9 1.3 6.5 6.7 0.1 3.9 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-like domain ING PF12998.7 OWF50515.1 - 3.5e-29 101.4 2.9 3.5e-29 101.4 2.9 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OWF50515.1 - 1.5e-06 28.0 7.7 2.6e-06 27.2 7.7 1.4 1 0 0 1 1 1 1 PHD-finger SR-25 PF10500.9 OWF50515.1 - 0.00073 19.2 5.4 0.0009 18.9 5.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PHD_2 PF13831.6 OWF50515.1 - 0.012 15.2 1.2 0.019 14.5 1.2 1.4 1 0 0 1 1 1 0 PHD-finger DUF4355 PF14265.6 OWF50515.1 - 0.088 13.0 12.7 3 8.1 8.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) zf-RING_UBOX PF13445.6 OWF50517.1 - 1.4e-09 37.8 6.1 1.4e-09 37.8 6.1 2.5 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF50517.1 - 2.5e-08 33.6 7.3 2.5e-08 33.6 7.3 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF50517.1 - 1.1e-06 28.8 7.1 1.1e-06 28.8 7.1 3.6 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF50517.1 - 2.2e-05 24.2 3.5 2.2e-05 24.2 3.5 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF50517.1 - 3.6e-05 23.8 20.0 6.2e-05 23.1 8.2 4.4 5 0 0 5 5 5 2 B-box zinc finger zf-RING_5 PF14634.6 OWF50517.1 - 9.9e-05 22.2 6.2 9.9e-05 22.2 6.2 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF50517.1 - 0.0001 22.4 8.0 0.0001 22.4 8.0 3.2 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF50517.1 - 0.00022 21.0 3.2 0.00022 21.0 3.2 2.9 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OWF50517.1 - 0.00033 20.4 6.6 0.00033 20.4 6.6 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MethyltransfD12 PF02086.15 OWF50517.1 - 0.011 15.5 1.3 0.023 14.4 1.3 1.5 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase FAM167 PF11652.8 OWF50517.1 - 3.2 8.3 7.7 5.7 7.5 0.4 3.8 3 1 1 4 4 4 0 FAM167 zf-RING_UBOX PF13445.6 OWF50518.1 - 3.1e-08 33.5 7.6 3.1e-08 33.5 7.6 3.6 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF50518.1 - 9e-08 31.9 9.6 9e-08 31.9 9.6 4.2 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) SBBP PF06739.11 OWF50518.1 - 2.9e-07 30.4 0.3 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 2 Beta-propeller repeat zf-B_box PF00643.24 OWF50518.1 - 6.6e-07 29.4 19.2 8.3e-05 22.7 2.9 4.2 5 0 0 5 5 5 2 B-box zinc finger zf-RING_2 PF13639.6 OWF50518.1 - 0.00014 22.2 8.0 0.00014 22.2 8.0 4.8 4 0 0 4 4 4 2 Ring finger domain zf-RING_5 PF14634.6 OWF50518.1 - 0.00031 20.7 8.6 0.00031 20.7 8.6 4.2 4 0 0 4 4 3 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF50518.1 - 0.00081 19.5 7.8 0.00081 19.5 7.8 3.8 5 0 0 5 5 3 1 zinc finger of C3HC4-type, RING zf-4CXXC_R1 PF10497.9 OWF50518.1 - 0.0021 18.2 3.4 0.0021 18.2 3.4 3.5 2 1 0 2 2 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_2 PF13923.6 OWF50518.1 - 0.0022 17.8 11.7 0.0022 17.8 11.7 4.3 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 OWF50518.1 - 0.025 14.6 4.3 0.19 11.8 0.2 3.2 3 0 0 3 3 3 0 NHL repeat Synaptobrevin PF00957.21 OWF50518.1 - 0.059 13.2 1.0 0.12 12.1 1.0 1.5 1 0 0 1 1 1 0 Synaptobrevin SGL PF08450.12 OWF50518.1 - 0.1 12.2 0.0 0.39 10.3 0.0 1.9 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region RNA_pol_Rpb2_7 PF04560.20 OWF50518.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.4 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 7 Fcf2 PF08698.11 OWF50519.1 - 6.3e-37 125.9 2.5 6.3e-37 125.9 2.5 2.5 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing TM2 PF05154.16 OWF50520.1 - 5.5e-14 52.2 5.6 1.3e-13 51.0 5.6 1.6 1 0 0 1 1 1 1 TM2 domain GOLGA2L5 PF15070.6 OWF50521.1 - 2.4e-85 287.5 92.5 2.4e-85 287.5 92.5 5.8 1 1 1 3 3 3 1 Putative golgin subfamily A member 2-like protein 5 TMF_TATA_bd PF12325.8 OWF50521.1 - 0.0061 16.8 21.0 0.0061 16.8 21.0 9.8 1 1 8 10 10 10 5 TATA element modulatory factor 1 TATA binding ANAPC5 PF12862.7 OWF50522.1 - 2.3e-30 104.5 8.9 3.8e-27 94.2 2.5 3.4 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 OWF50522.1 - 1.5e-08 34.8 11.8 0.0053 17.0 0.8 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF50522.1 - 1.4e-05 24.8 1.1 0.0042 16.9 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 OWF50522.1 - 3.9e-05 23.4 0.6 0.0017 18.1 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 OWF50522.1 - 0.00049 20.1 1.5 2.8 8.4 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF50522.1 - 0.00092 19.1 0.7 3.6 7.9 0.8 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.11 OWF50522.1 - 0.0011 16.4 1.4 0.25 8.6 0.2 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_14 PF13428.6 OWF50522.1 - 0.003 18.3 4.1 5.4 8.1 0.5 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 OWF50522.1 - 0.0034 17.9 5.5 2.4 9.0 2.9 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF50522.1 - 0.0076 16.7 7.1 2.9 8.4 0.0 5.7 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 OWF50522.1 - 0.027 14.8 3.1 8.8 6.7 0.0 4.4 2 2 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF50522.1 - 0.037 14.0 5.0 2 8.6 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF50522.1 - 0.048 14.3 5.4 75 4.3 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF50522.1 - 0.24 12.1 3.3 8.9 7.1 0.5 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_47 PF01532.20 OWF50523.1 - 1e-117 393.9 0.1 2.1e-117 392.9 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 OWF50523.1 - 2.8e-10 40.1 0.0 6.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 PA domain C5-epim_C PF06662.13 OWF50523.1 - 0.098 12.2 0.3 15 5.0 0.1 2.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus DUF2358 PF10184.9 OWF50524.1 - 2.5e-07 31.0 2.2 4.7e-07 30.1 2.2 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DSPc PF00782.20 OWF50525.1 - 3e-28 98.3 0.0 4.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF50525.1 - 0.00043 19.9 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.14 OWF50525.1 - 0.0089 16.2 0.2 0.043 14.0 0.1 2.0 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 OWF50525.1 - 0.038 12.8 2.5 0.38 9.6 0.2 2.1 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-HIT PF04438.16 OWF50525.1 - 0.078 12.9 2.1 7 6.6 0.1 2.5 2 0 0 2 2 2 0 HIT zinc finger JmjC PF02373.22 OWF50526.1 - 2.2e-26 92.5 1.4 1.6e-25 89.8 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OWF50526.1 - 2.8e-21 76.4 1.6 3.1e-21 76.2 0.3 1.7 1 1 1 2 2 2 1 Cupin-like domain CDC45 PF02724.14 OWF50526.1 - 5.7 5.1 14.0 8.7 4.5 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein 7tm_1 PF00001.21 OWF50527.1 - 4.3e-35 121.3 10.4 6e-35 120.8 10.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4834 PF16118.5 OWF50527.1 - 0.0045 17.9 0.6 0.0045 17.9 0.6 2.7 1 1 0 2 2 2 1 Domain of unknown function (DUF4834) Shisa PF13908.6 OWF50527.1 - 0.0047 17.2 0.5 0.0047 17.2 0.5 2.2 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator DUF2981 PF11200.8 OWF50527.1 - 0.014 15.2 0.4 0.023 14.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Tmemb_9 PF05434.11 OWF50527.1 - 0.078 12.9 0.1 0.078 12.9 0.1 2.2 3 1 0 3 3 3 0 TMEM9 DUF2633 PF11119.8 OWF50527.1 - 0.41 10.6 8.3 2.1 8.3 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) CrgA PF06781.12 OWF50527.1 - 1.6 8.8 3.9 24 5.1 0.0 3.6 4 0 0 4 4 4 0 Cell division protein CrgA DUF4605 PF15378.6 OWF50527.1 - 9.1 6.2 9.8 0.31 10.9 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) zf-RING_9 PF13901.6 OWF50529.1 - 4.9e-50 170.4 14.6 3.8e-44 151.1 2.4 2.4 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 OWF50529.1 - 4.2e-05 23.3 14.3 4.2e-05 23.3 14.3 2.9 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SUIM_assoc PF16619.5 OWF50529.1 - 0.76 9.9 4.1 27 4.9 0.0 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 C1_2 PF03107.16 OWF50529.1 - 3 8.2 22.3 1.9 8.9 8.7 3.6 3 0 0 3 3 3 0 C1 domain BAR_3_WASP_bdg PF10456.9 OWF50530.1 - 6.6e-84 281.0 7.3 6.6e-84 281.0 7.3 1.6 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 OWF50530.1 - 9.1e-24 83.6 1.6 2.1e-23 82.5 0.2 2.3 2 0 0 2 2 2 1 PX domain SH3_1 PF00018.28 OWF50530.1 - 1.2e-11 44.1 0.8 6.4e-11 41.7 0.2 2.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OWF50530.1 - 2.9e-09 36.6 0.7 6.5e-09 35.5 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OWF50530.1 - 4e-08 32.8 0.0 1.2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 OWF50530.1 - 0.00017 21.2 0.9 0.11 12.0 2.6 2.6 1 1 1 2 2 2 2 Vps5 C terminal like OTCace PF00185.24 OWF50530.1 - 0.001 19.2 0.9 0.13 12.3 0.4 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain HBM PF16591.5 OWF50530.1 - 0.028 13.9 0.9 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Helical bimodular sensor domain EST1 PF10374.9 OWF50530.1 - 0.074 13.7 1.4 0.24 12.0 1.3 1.9 1 1 0 1 1 1 0 Telomerase activating protein Est1 Tetraspanin PF00335.20 OWF50531.1 - 3.8e-31 108.6 15.5 4.7e-31 108.3 15.5 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 OWF50531.1 - 8.7 5.0 6.3 15 4.2 5.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF829 PF05705.14 OWF50533.1 - 8.7e-37 127.3 0.0 1.2e-36 126.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_3 PF07859.13 OWF50533.1 - 0.00056 19.8 0.0 0.00081 19.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF50533.1 - 0.019 14.3 0.0 6.6 5.9 0.0 2.3 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Gsf2 PF11055.8 OWF50533.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 DUF829 PF05705.14 OWF50534.1 - 1.2e-38 133.3 0.0 1.6e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Hydrolase_4 PF12146.8 OWF50534.1 - 0.016 14.5 0.0 2.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 SEFIR PF08357.11 OWF50536.1 - 4.1e-08 33.6 0.4 1.1e-06 28.9 0.2 2.7 2 1 0 2 2 2 1 SEFIR domain zf-C2H2_6 PF13912.6 OWF50537.1 - 0.0094 15.9 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF50537.1 - 0.01 16.1 3.2 0.018 15.4 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OWF50537.1 - 0.015 16.1 6.0 0.057 14.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger ATPase PF06745.13 OWF50537.1 - 0.16 11.3 1.8 0.47 9.8 0.8 1.9 2 0 0 2 2 2 0 KaiC zf-C2H2 PF00096.26 OWF50537.1 - 0.29 11.7 0.1 0.29 11.7 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2HC_14 PF18574.1 OWF50537.1 - 0.83 9.5 4.7 1 9.2 0.4 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain Ank_2 PF12796.7 OWF50538.1 - 8.2e-45 151.3 1.4 2.3e-12 47.3 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50538.1 - 1.2e-41 140.5 4.8 5.9e-07 29.9 0.5 9.3 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF50538.1 - 7.8e-33 112.1 9.7 1.5e-07 31.6 0.1 8.5 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF50538.1 - 4.2e-32 109.2 3.0 2.1e-06 27.9 0.1 10.1 9 1 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 OWF50538.1 - 7.9e-31 102.6 11.3 1.5e-07 31.1 0.1 10.9 11 0 0 11 11 11 6 Ankyrin repeat CH PF00307.31 OWF50538.1 - 8e-07 29.2 1.6 1.4e-05 25.2 0.0 3.2 4 0 0 4 4 4 1 Calponin homology (CH) domain Snf7 PF03357.21 OWF50538.1 - 0.028 14.0 0.3 0.06 12.9 0.3 1.5 1 0 0 1 1 1 0 Snf7 HCNGP PF07818.13 OWF50539.1 - 7.4e-33 113.1 0.0 1.5e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein Kinesin PF00225.23 OWF50540.1 - 7.1e-110 367.0 1.2 1.3e-109 366.2 1.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF50540.1 - 1.2e-60 203.8 0.5 2.6e-60 202.7 0.1 1.9 2 0 0 2 2 2 1 Microtubule binding CENP-F_leu_zip PF10473.9 OWF50540.1 - 1.4e-06 28.3 23.3 0.0069 16.4 7.4 2.9 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OWF50540.1 - 0.00013 21.0 9.4 0.00013 21.0 9.4 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein KASH_CCD PF14662.6 OWF50540.1 - 0.00043 20.2 15.4 0.0012 18.7 15.4 1.7 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 OWF50540.1 - 0.0056 17.3 9.1 1 10.0 0.4 3.8 2 1 1 3 3 3 1 SlyX AAA_13 PF13166.6 OWF50540.1 - 0.0066 15.2 12.7 0.017 13.8 12.7 1.6 1 0 0 1 1 1 1 AAA domain DUF3450 PF11932.8 OWF50540.1 - 0.008 15.5 6.1 0.008 15.5 6.1 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF3450) Lebercilin PF15619.6 OWF50540.1 - 0.027 14.1 24.3 0.025 14.2 9.6 2.7 3 0 0 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease Myosin_tail_1 PF01576.19 OWF50540.1 - 0.059 11.2 21.9 0.091 10.6 21.9 1.2 1 0 0 1 1 1 0 Myosin tail DUF812 PF05667.11 OWF50540.1 - 0.072 12.0 18.1 0.21 10.4 18.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) BRE1 PF08647.11 OWF50540.1 - 0.2 11.7 16.9 0.044 13.8 3.0 3.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 OWF50540.1 - 0.26 11.1 18.4 1.1 9.1 4.3 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 OWF50540.1 - 0.34 11.3 10.3 1.9 8.8 3.3 3.1 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 OWF50540.1 - 0.34 11.2 7.9 1.1 9.6 0.1 3.8 1 1 3 4 4 4 0 Tup N-terminal DUF5082 PF16888.5 OWF50540.1 - 0.38 11.0 16.5 2.3 8.5 3.2 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 OWF50540.1 - 0.52 10.5 14.3 1.3 9.2 2.3 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OWF50540.1 - 0.57 10.2 8.7 0.036 14.1 2.3 2.4 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 OWF50540.1 - 0.76 9.2 19.2 0.069 12.6 10.2 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 CREPT PF16566.5 OWF50540.1 - 1 9.5 11.3 3.2 7.9 2.4 3.0 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SYCE1 PF15233.6 OWF50540.1 - 1.5 8.9 14.6 0.51 10.4 3.0 2.7 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Filament PF00038.21 OWF50540.1 - 2.2 7.8 22.4 0.37 10.3 8.3 2.8 2 1 2 4 4 4 0 Intermediate filament protein Cortex-I_coil PF09304.10 OWF50540.1 - 3.2 8.0 14.6 0.11 12.8 1.2 3.7 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF1664 PF07889.12 OWF50540.1 - 3.7 7.6 9.5 1.4 9.0 1.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 OWF50540.1 - 3.8 7.9 16.2 1.9 8.9 4.5 3.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Occludin_ELL PF07303.13 OWF50540.1 - 4 8.2 7.6 18 6.2 0.8 2.9 2 1 0 2 2 2 0 Occludin homology domain YabA PF06156.13 OWF50540.1 - 6.7 7.4 18.9 22 5.7 2.0 5.5 4 1 1 6 6 6 0 Initiation control protein YabA DUF4407 PF14362.6 OWF50540.1 - 7.9 5.7 14.2 33 3.7 14.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Kinesin PF00225.23 OWF50541.1 - 2.5e-109 365.2 0.3 2.5e-109 365.2 0.3 3.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OWF50541.1 - 4e-27 95.0 0.1 4e-27 95.0 0.1 4.1 4 1 0 4 4 4 1 Microtubule binding CobD_Cbib PF03186.13 OWF50541.1 - 0.12 11.5 0.0 0.45 9.7 0.0 1.9 2 0 0 2 2 2 0 CobD/Cbib protein GlcNAc-1_reg PF18440.1 OWF50541.1 - 0.2 11.9 0.0 0.2 11.9 0.0 4.1 4 0 0 4 4 4 0 Putative GlcNAc-1 phosphotransferase regulatory domain Casc1_N PF15927.5 OWF50542.1 - 1.1e-49 168.8 19.4 1.1e-49 168.8 19.4 3.6 2 2 1 3 3 3 1 Cancer susceptibility candidate 1 N-terminus MFS_1 PF07690.16 OWF50543.1 - 1.2e-23 83.6 62.9 3.4e-13 49.2 14.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 OWF50543.1 - 0.00021 20.7 21.0 0.028 13.7 3.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF3671 PF12420.8 OWF50543.1 - 0.061 13.4 13.5 0.23 11.5 3.5 3.8 3 1 0 3 3 3 0 Protein of unknown function SIT PF15330.6 OWF50543.1 - 0.38 11.2 1.2 21 5.6 0.0 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Stevor PF17410.2 OWF50543.1 - 2.4 7.6 6.3 0.18 11.3 0.4 2.1 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Dicty_REP PF05086.12 OWF50543.1 - 3.5 5.5 10.6 6.5 4.6 10.6 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF443 PF04276.12 OWF50543.1 - 8.7 6.1 17.1 0.016 15.0 2.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF443) YIF1 PF03878.15 OWF50544.1 - 6.5e-06 25.8 6.7 0.0001 21.9 6.7 2.1 1 1 0 1 1 1 1 YIF1 Yip1 PF04893.17 OWF50544.1 - 8.9e-06 25.5 17.0 2.6e-05 24.0 16.6 1.8 1 1 1 2 2 2 1 Yip1 domain DUF4692 PF15763.5 OWF50544.1 - 0.1 13.1 0.1 0.16 12.4 0.1 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF4271 PF14093.6 OWF50544.1 - 3 7.7 14.3 0.37 10.7 9.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) TMEM117 PF15113.6 OWF50545.1 - 2.7e-189 629.3 25.5 3.2e-189 629.1 25.5 1.0 1 0 0 1 1 1 1 TMEM117 protein family SDF PF00375.18 OWF50546.1 - 8.9e-88 294.9 26.2 1.1e-87 294.7 26.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Sulfotransfer_2 PF03567.14 OWF50547.1 - 5.6e-29 101.8 1.8 1.9e-24 87.0 0.2 2.3 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF50547.1 - 0.024 14.1 0.1 0.18 11.2 0.1 2.2 1 1 0 1 1 1 0 Sulfotransferase domain Sulfotransfer_1 PF00685.27 OWF50548.1 - 1.4e-47 162.4 1.2 5.3e-47 160.5 1.2 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF50548.1 - 5.1e-07 30.3 0.1 3e-05 24.5 0.0 2.4 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF50548.1 - 0.024 14.6 0.1 0.04 13.8 0.1 1.5 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF50549.1 - 2.9e-46 158.1 1.1 1.1e-45 156.2 1.1 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF50549.1 - 4.3e-06 27.3 0.0 3.1e-05 24.5 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF50549.1 - 0.021 14.7 0.1 0.035 14.0 0.1 1.5 1 1 0 1 1 1 0 Sulfotransferase family Ald_Xan_dh_C2 PF02738.18 OWF50550.1 - 3.4e-179 596.8 0.0 5.2e-179 596.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OWF50550.1 - 1.4e-35 122.6 0.0 2.4e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 OWF50550.1 - 8e-30 103.4 0.0 1.6e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OWF50550.1 - 1.5e-24 85.8 1.1 4.2e-23 81.2 0.7 2.8 2 0 0 2 2 2 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OWF50550.1 - 9.7e-24 83.5 0.0 3.3e-23 81.8 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Peptidase_M14 PF00246.24 OWF50551.1 - 1.5e-19 70.9 0.0 6.8e-19 68.8 0.0 2.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OWF50551.1 - 6.8e-17 61.8 7.0 8.9e-17 61.4 3.1 2.8 3 0 0 3 3 3 1 Cytosolic carboxypeptidase N-terminal domain Ribosomal_L39 PF00832.20 OWF50552.1 - 3.1e-24 84.3 13.9 3.9e-24 84.0 13.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_L28e PF01778.17 OWF50552.1 - 0.014 16.1 0.3 0.015 16.0 0.3 1.1 1 0 0 1 1 1 0 Ribosomal L28e protein family TraN PF06986.11 OWF50552.1 - 0.037 13.7 1.4 0.043 13.5 1.4 1.1 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation RabGAP-TBC PF00566.18 OWF50553.1 - 5.1e-09 36.1 0.4 3.5e-07 30.1 0.1 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain zf-RING_2 PF13639.6 OWF50554.1 - 3.3e-10 40.1 3.5 1e-09 38.6 3.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OWF50554.1 - 3.9e-08 33.0 1.1 3.9e-08 33.0 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF50554.1 - 1.7e-07 30.9 2.6 1.7e-07 30.9 2.6 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF50554.1 - 4.9e-07 29.7 4.2 1.4e-06 28.3 4.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF50554.1 - 5.4e-06 26.2 0.9 5.4e-06 26.2 0.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF50554.1 - 6.3e-06 26.1 2.2 1.8e-05 24.6 2.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OWF50554.1 - 0.00015 22.0 6.5 0.00035 20.8 5.2 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OWF50554.1 - 0.00036 20.3 5.1 0.0076 16.1 0.3 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OWF50554.1 - 0.00061 19.9 2.7 0.0038 17.3 2.9 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OWF50554.1 - 0.0013 18.4 1.1 0.0034 17.1 1.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger WD40 PF00400.32 OWF50554.1 - 0.0075 17.1 0.4 15 6.7 0.0 5.1 5 0 0 5 5 4 0 WD domain, G-beta repeat zf-UDP PF14569.6 OWF50554.1 - 0.0078 16.3 0.4 0.022 14.8 0.4 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 OWF50554.1 - 0.0096 15.7 1.7 0.028 14.2 1.7 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OWF50554.1 - 0.012 15.6 1.2 0.053 13.6 1.2 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OWF50554.1 - 0.015 15.1 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 OWF50554.1 - 0.099 12.8 2.1 0.27 11.4 2.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger FANCL_C PF11793.8 OWF50554.1 - 0.13 12.5 5.6 1.5 9.0 5.6 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OWF50554.1 - 0.19 11.3 2.4 0.55 9.9 2.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ADH_zinc_N PF00107.26 OWF50555.1 - 5.9e-28 97.5 0.0 9.8e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF50555.1 - 4.7e-13 50.4 0.0 9.6e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF50555.1 - 9.6e-11 41.5 0.3 3.6e-09 36.5 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OWF50555.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 OWF50555.1 - 0.029 13.8 0.1 0.078 12.4 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Big_2 PF02368.18 OWF50557.1 - 1.5e-09 37.6 13.1 0.016 15.1 0.0 8.5 9 1 0 9 9 9 4 Bacterial Ig-like domain (group 2) SH3_2 PF07653.17 OWF50558.1 - 1.2e-23 82.5 2.3 3.1e-11 42.8 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 OWF50558.1 - 8e-22 76.6 1.2 2.8e-15 55.7 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 OWF50558.1 - 2.8e-18 65.8 0.0 4.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 OWF50558.1 - 5.1e-15 55.1 0.0 2.4e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 OWF50558.1 - 4.3e-07 30.3 0.0 9e-06 26.0 0.0 2.6 3 0 0 3 3 3 1 Helically-extended SH3 domain SH2_2 PF14633.6 OWF50558.1 - 0.039 13.4 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 SH2 domain SH3_10 PF17902.1 OWF50558.1 - 0.067 13.3 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 SH3 domain Forkhead PF00250.18 OWF50559.1 - 1.5e-14 54.0 0.0 2.2e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 Forkhead domain Hormone_1 PF00103.20 OWF50559.1 - 0.065 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Glyco_transf_10 PF00852.19 OWF50560.1 - 5.2e-23 81.7 0.2 6.2e-23 81.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_transf_10 PF00852.19 OWF50561.1 - 1.8e-29 102.7 0.1 2.7e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF50561.1 - 5.6e-26 91.2 0.0 1.1e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal zf_C2HC_14 PF18574.1 OWF50561.1 - 0.035 13.9 0.3 0.097 12.5 0.3 1.7 1 0 0 1 1 1 0 C2HC Zing finger domain CdhD PF03599.16 OWF50562.1 - 5.9 5.5 6.8 65 2.1 6.9 2.3 1 1 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Haem_bd PF14376.6 OWF50563.1 - 0.00036 20.5 0.7 0.75 9.7 0.0 2.6 1 1 2 3 3 3 2 Haem-binding domain Casein PF00363.18 OWF50564.1 - 3.8 7.9 11.7 18 5.8 3.2 2.7 1 1 1 2 2 2 0 Casein CLN3 PF02487.17 OWF50565.1 - 1.4e-61 208.7 11.4 1.9e-61 208.3 11.4 1.1 1 0 0 1 1 1 1 CLN3 protein Lip_A_acyltrans PF03279.13 OWF50565.1 - 0.13 11.4 1.5 8.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase SH3_9 PF14604.6 OWF50566.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF50566.1 - 0.0028 17.2 0.0 0.0092 15.6 0.0 2.0 1 1 0 1 1 1 1 SH3 domain FCH PF00611.23 OWF50566.1 - 0.003 17.8 0.1 0.0085 16.4 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Lipocalin PF00061.23 OWF50567.1 - 0.012 15.8 0.5 0.013 15.7 0.5 1.1 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Flavodoxin_NdrI PF07972.11 OWF50567.1 - 0.03 14.5 0.0 0.064 13.4 0.0 1.5 1 1 1 2 2 2 0 NrdI Flavodoxin like Vps36-NZF-N PF16988.5 OWF50567.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36-NZF-N PF16988.5 OWF50568.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Lipocalin_7 PF14651.6 OWF50570.1 - 0.002 18.1 2.6 0.003 17.5 2.6 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 OWF50571.1 - 0.0091 15.9 0.3 0.013 15.4 0.3 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 OWF50572.1 - 2e-06 27.7 0.3 4.3e-06 26.7 0.1 1.5 1 1 1 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1972 PF09314.11 OWF50572.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) NusG_II PF07009.11 OWF50572.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 NusG domain II DEAD PF00270.29 OWF50574.1 - 0.00067 19.5 0.0 0.00089 19.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Annexin PF00191.20 OWF50575.1 - 1.3e-06 28.3 32.3 0.032 14.3 0.1 8.7 5 2 3 9 9 9 3 Annexin GerPC PF10737.9 OWF50575.1 - 0.026 14.6 12.8 0.14 12.2 3.5 2.7 1 1 2 3 3 3 0 Spore germination protein GerPC Bactofilin PF04519.13 OWF50575.1 - 0.034 14.4 12.5 0.4 11.0 0.4 4.4 2 2 1 3 3 3 0 Polymer-forming cytoskeletal Fibrinogen_BP PF08017.11 OWF50575.1 - 0.26 9.7 17.6 0.39 9.1 17.6 1.3 1 0 0 1 1 1 0 Fibrinogen binding protein ARGLU PF15346.6 OWF50575.1 - 1.6 8.6 34.5 3.2 7.6 2.7 4.0 1 1 3 4 4 4 0 Arginine and glutamate-rich 1 Xrn1_D3 PF18194.1 OWF50575.1 - 3.3 7.9 6.5 52 4.0 0.1 4.0 4 0 0 4 4 4 0 Exoribonuclease 1 Domain-3 Annexin PF00191.20 OWF50576.1 - 0.0027 17.7 4.5 2.7 8.2 0.2 3.3 1 1 2 3 3 3 3 Annexin Bactofilin PF04519.13 OWF50576.1 - 0.086 13.1 0.2 0.19 12.1 0.2 1.7 1 1 0 1 1 1 0 Polymer-forming cytoskeletal Bactofilin PF04519.13 OWF50577.1 - 0.0011 19.2 4.1 0.008 16.5 1.0 2.8 1 1 1 2 2 2 2 Polymer-forming cytoskeletal Annexin PF00191.20 OWF50577.1 - 0.0066 16.5 19.4 2.4 8.3 0.2 6.2 1 1 3 6 6 6 5 Annexin SGP PF17228.2 OWF50577.1 - 0.56 11.1 10.3 27 5.7 0.8 3.3 2 1 1 3 3 3 0 Sulphur globule protein Spore_GerAC PF05504.11 OWF50577.1 - 1.4 9.1 7.5 1 9.6 2.6 2.2 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Lipocalin_7 PF14651.6 OWF50578.1 - 0.004 17.1 0.6 0.0054 16.7 0.6 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 OWF50579.1 - 0.085 12.8 0.1 0.11 12.5 0.1 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family DUF2335 PF10097.9 OWF50581.1 - 0.00017 21.5 0.2 15 5.7 0.0 7.4 9 0 0 9 9 9 1 Predicted membrane protein (DUF2335) DUF538 PF04398.12 OWF50581.1 - 0.12 12.8 0.2 12 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF538 DUF2661 PF10860.8 OWF50581.1 - 0.2 11.7 0.9 0.83 9.8 0.9 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) ApoL PF05461.11 OWF50582.1 - 2.8e-14 53.2 3.9 8e-08 32.0 2.0 2.0 1 1 1 2 2 2 2 Apolipoprotein L Linker_histone PF00538.19 OWF50583.1 - 9.2e-26 90.0 1.8 9.2e-26 90.0 1.8 2.4 3 0 0 3 3 3 1 linker histone H1 and H5 family HC2 PF07382.11 OWF50583.1 - 6.1e-05 23.2 36.7 6.1e-05 23.2 36.7 3.4 1 1 1 2 2 2 1 Histone H1-like nucleoprotein HC2 7tm_1 PF00001.21 OWF50584.1 - 2.5e-18 66.3 4.8 3.6e-18 65.9 4.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HORMA PF02301.18 OWF50585.1 - 6.8e-62 208.8 1.7 9.8e-62 208.3 0.0 2.0 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 OWF50585.1 - 0.00024 21.0 8.7 0.00061 19.6 8.7 1.8 1 0 0 1 1 1 1 PHD-finger Sin3_corepress PF08295.12 OWF50585.1 - 0.011 15.8 0.1 0.011 15.8 0.1 2.3 3 1 0 3 3 3 0 Sin3 family co-repressor MarR_2 PF12802.7 OWF50585.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 MarR family Ribosomal_S25 PF03297.15 OWF50585.1 - 0.7 10.1 0.0 0.7 10.1 0.0 3.3 3 0 0 3 3 3 0 S25 ribosomal protein S_layer_C PF05124.12 OWF50585.1 - 2.7 8.0 7.1 8.1 6.4 6.9 1.9 1 1 0 1 1 1 0 S-layer like family, C-terminal region RIIa PF02197.17 OWF50586.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit U1snRNP70_N PF12220.8 OWF50588.1 - 7.9e-26 90.5 3.5 7.9e-26 90.5 3.5 2.8 3 1 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 OWF50588.1 - 2.1e-16 59.5 0.0 3.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF50588.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ion_trans PF00520.31 OWF50589.1 - 3.5e-49 167.3 13.0 4.4e-49 166.9 13.0 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF50589.1 - 1e-28 99.5 0.1 2.2e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF50589.1 - 1.6e-13 50.4 4.6 1.6e-13 50.4 4.6 2.9 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 OWF50589.1 - 0.0056 15.4 0.9 0.0056 15.4 0.9 2.2 1 1 1 2 2 2 1 Polycystin cation channel BTB_3 PF16017.5 OWF50589.1 - 0.033 14.3 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain YrhC PF14143.6 OWF50589.1 - 0.22 11.7 7.4 0.23 11.6 0.1 3.0 3 0 0 3 3 3 0 YrhC-like protein Sigma_reg_N PF13800.6 OWF50589.1 - 8.5 6.7 7.6 16 5.9 0.1 3.7 4 0 0 4 4 4 0 Sigma factor regulator N-terminal LPAM_2 PF13627.6 OWF50590.1 - 0.27 11.1 78.7 90 3.1 0.1 18.5 19 0 0 19 19 19 0 Prokaryotic lipoprotein-attachment site DUF3672 PF12421.8 OWF50591.1 - 6.8e-05 22.8 0.0 15 5.5 0.0 5.6 1 1 5 6 6 6 4 Fibronectin type III protein Lipocalin PF00061.23 OWF50592.1 - 0.039 14.2 0.0 0.064 13.4 0.0 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 OWF50593.1 - 0.00059 20.1 0.1 0.0021 18.2 0.0 1.9 2 0 0 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF50593.1 - 0.074 12.9 0.3 0.41 10.5 0.0 2.2 3 0 0 3 3 3 0 Triabin Tetraspanin PF00335.20 OWF50595.1 - 6.2e-49 166.8 14.5 7.4e-49 166.5 14.5 1.1 1 0 0 1 1 1 1 Tetraspanin family CcmD PF04995.14 OWF50595.1 - 0.47 10.6 2.7 2.2 8.4 2.7 2.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Med18 PF09637.10 OWF50596.1 - 1.1e-29 104.0 0.1 2.8e-23 83.0 0.1 2.1 1 1 1 2 2 2 2 Med18 protein Claudin_2 PF13903.6 OWF50597.1 - 2.7e-22 79.5 4.5 3.6e-22 79.1 4.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF50597.1 - 9.6e-12 45.1 10.8 3.4e-08 33.6 4.1 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 OWF50597.1 - 0.00032 20.2 5.9 0.00064 19.2 5.9 1.5 1 1 0 1 1 1 1 Clc-like DuoxA PF10204.9 OWF50597.1 - 1.5 7.7 8.4 0.19 10.7 2.6 2.1 2 1 0 2 2 2 0 Dual oxidase maturation factor DBC1 PF14443.6 OWF50599.1 - 2.3e-48 163.3 0.0 2.3e-48 163.3 0.0 2.8 3 0 0 3 3 3 1 DBC1 S1-like PF14444.6 OWF50599.1 - 2.5e-30 104.2 0.9 5.1e-30 103.2 0.9 1.5 1 0 0 1 1 1 1 S1-like SAP PF02037.27 OWF50599.1 - 5.5e-08 32.4 0.8 5.5e-08 32.4 0.8 2.6 3 0 0 3 3 3 1 SAP domain Amino_oxidase PF01593.24 OWF50600.1 - 0.00017 21.0 0.5 0.00024 20.5 0.5 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Peptidase_C14 PF00656.22 OWF50601.1 - 2.1e-15 57.3 0.1 3.8e-15 56.5 0.1 1.4 1 1 0 1 1 1 1 Caspase domain ARA70 PF12489.8 OWF50602.1 - 1e-06 29.0 14.6 0.00043 20.5 0.2 5.6 6 1 1 7 7 7 3 Nuclear coactivator Stork_head PF10264.9 OWF50603.1 - 4.9e-29 100.3 0.2 9.7e-29 99.4 0.2 1.5 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain WBP-1 PF11669.8 OWF50603.1 - 2.8 8.6 6.3 12 6.6 0.8 3.2 2 0 0 2 2 2 0 WW domain-binding protein 1 RRM_1 PF00076.22 OWF50604.1 - 5e-12 45.5 0.0 9.1e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rho_GDI PF02115.17 OWF50605.1 - 1.1e-61 208.0 3.7 1.3e-61 207.7 3.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Phosducin PF02114.16 OWF50605.1 - 0.13 11.2 2.3 0.18 10.7 2.3 1.2 1 0 0 1 1 1 0 Phosducin Pyr_redox_2 PF07992.14 OWF50606.1 - 7.8e-10 38.5 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF50606.1 - 0.0072 16.5 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OWF50606.1 - 0.051 14.0 0.0 5.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OWF50606.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OWF50606.1 - 0.2 10.3 0.0 0.35 9.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Sad1_UNC PF07738.13 OWF50607.1 - 5.2e-41 139.7 0.0 2.8e-40 137.4 0.0 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Ependymin PF00811.18 OWF50608.1 - 3.3e-17 62.9 0.1 4.5e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Ependymin LRR_4 PF12799.7 OWF50609.1 - 1.5e-28 98.4 29.6 4.6e-09 36.4 2.0 7.3 5 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF50609.1 - 9.9e-20 70.1 21.5 9.3e-06 25.3 2.0 5.3 1 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 OWF50609.1 - 3.5e-14 52.7 3.8 4.7e-07 29.5 0.0 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 OWF50609.1 - 0.047 14.2 25.6 36 5.5 0.2 8.4 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF50609.1 - 0.068 13.3 19.7 9 6.6 0.2 8.3 8 1 1 9 9 9 0 Leucine Rich repeat DUF3432 PF11914.8 OWF50610.1 - 2.1 8.6 20.8 4.4 7.6 3.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Ras PF00071.22 OWF50611.1 - 8.5e-39 132.7 0.2 1e-38 132.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50611.1 - 2.6e-17 63.2 0.0 3.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50611.1 - 4.5e-06 26.2 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF50611.1 - 5.3e-05 23.2 0.1 0.056 13.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF50611.1 - 6e-05 23.1 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OWF50611.1 - 0.014 15.4 0.3 0.022 14.8 0.3 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 OWF50611.1 - 0.034 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DnaJ PF00226.31 OWF50612.1 - 2.8e-22 78.6 0.5 5.4e-22 77.7 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain zf-BED PF02892.15 OWF50612.1 - 0.014 15.4 0.3 0.56 10.3 0.1 2.7 2 0 0 2 2 2 0 BED zinc finger PyrI_C PF02748.15 OWF50612.1 - 0.032 14.1 0.1 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain JHY PF15261.6 OWF50612.1 - 0.035 14.8 0.4 0.035 14.8 0.4 3.4 3 1 0 3 3 2 0 Jhy protein zf-C2HC_2 PF13913.6 OWF50612.1 - 0.039 13.9 9.6 0.077 12.9 1.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 OWF50612.1 - 0.12 13.3 8.8 2 9.5 0.3 3.5 3 0 0 3 3 2 0 C2H2-type zinc finger zf-AN1 PF01428.16 OWF50612.1 - 0.14 12.4 0.5 9.8 6.4 0.0 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf-CHCC PF10276.9 OWF50612.1 - 0.18 11.9 2.4 0.36 10.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger domain HNH PF01844.23 OWF50612.1 - 0.4 10.9 1.9 0.51 10.6 0.3 2.1 2 0 0 2 2 2 0 HNH endonuclease YacG PF03884.14 OWF50612.1 - 1.1 9.1 5.0 6.3 6.6 0.4 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-C2H2 PF00096.26 OWF50612.1 - 2.2 8.9 9.1 2.5 8.7 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Neur_chan_LBD PF02931.23 OWF50615.1 - 4.1e-38 131.0 0.4 6.6e-38 130.3 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50615.1 - 1.6e-22 80.8 8.5 3.1e-22 79.8 7.4 1.9 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF1569 PF07606.11 OWF50615.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Neur_chan_LBD PF02931.23 OWF50616.1 - 2.8e-25 89.1 0.3 2.8e-25 89.1 0.3 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF50616.1 - 6.8e-21 75.4 3.9 9.7e-21 74.9 3.6 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CUB PF00431.20 OWF50618.1 - 3.3e-13 49.9 0.1 3.1e-10 40.4 0.0 2.9 2 0 0 2 2 2 2 CUB domain fn3 PF00041.21 OWF50619.1 - 6.7e-50 167.4 0.0 2.4e-10 40.6 0.1 5.5 5 0 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF50619.1 - 4.7e-08 33.5 6.9 2.6 8.7 0.4 5.9 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF50619.1 - 2.9e-07 30.8 1.6 0.48 10.8 0.2 5.4 5 0 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III AIG1 PF04548.16 OWF50619.1 - 5.3e-07 29.2 0.7 1.9e-06 27.4 0.7 1.8 1 1 0 1 1 1 1 AIG1 family Septin PF00735.18 OWF50619.1 - 5.4e-07 29.2 0.1 1.1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Septin AAA_29 PF13555.6 OWF50619.1 - 2.2e-05 24.1 0.1 4.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OWF50619.1 - 9.9e-05 22.4 0.0 0.00033 20.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF50619.1 - 0.00021 20.9 0.2 0.0005 19.7 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OWF50619.1 - 0.0068 16.3 0.2 0.022 14.7 0.2 1.8 1 1 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 OWF50619.1 - 0.0094 16.3 0.2 1.5 9.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 OWF50619.1 - 0.017 15.6 0.7 0.066 13.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OWF50619.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2369 PF10179.9 OWF50619.1 - 0.02 15.2 0.4 20 5.6 0.0 4.2 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) ABC_tran PF00005.27 OWF50619.1 - 0.026 15.1 0.0 0.073 13.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Arylsulfotran_N PF17425.2 OWF50619.1 - 0.045 13.8 0.0 10 6.2 0.0 3.5 4 0 0 4 4 3 0 Arylsulfotransferase Ig-like domain SMC_N PF02463.19 OWF50619.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OWF50619.1 - 0.053 14.1 0.8 0.59 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 OWF50619.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 OWF50619.1 - 0.084 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 OWF50619.1 - 0.092 13.1 0.2 0.39 11.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OWF50619.1 - 0.28 10.9 1.1 1.2 8.8 0.1 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Tissue_fac PF01108.17 OWF50619.1 - 0.53 10.1 11.2 18 5.2 0.9 5.1 5 1 1 6 6 6 0 Tissue factor BACK PF07707.15 OWF50620.1 - 7.5e-28 96.6 4.5 1.5e-26 92.4 2.3 2.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF50620.1 - 3.5e-27 94.8 0.6 1.1e-26 93.3 0.1 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.25 OWF50620.1 - 4.5e-25 87.0 3.6 1.5e-11 43.7 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OWF50620.1 - 3.5e-24 84.2 1.2 5.1e-08 32.9 0.0 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 OWF50620.1 - 6.9e-10 38.8 6.3 0.0042 17.1 0.0 5.0 3 2 1 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF50620.1 - 8.6e-09 35.0 2.4 0.0053 16.7 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 OWF50620.1 - 9.4e-09 35.1 6.5 0.002 18.0 0.2 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OWF50620.1 - 2.8e-06 27.5 0.0 0.61 10.4 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF3342 PF11822.8 OWF50620.1 - 0.0087 16.2 1.1 0.067 13.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) BTB_2 PF02214.22 OWF50620.1 - 0.13 12.6 0.1 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Peptidase_M13_N PF05649.13 OWF50621.1 - 7.4e-104 348.5 1.0 1.1e-103 347.9 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF50621.1 - 8e-68 228.1 0.1 1.5e-67 227.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 Neuralized PF07177.12 OWF50622.1 - 3.4e-15 56.3 0.3 2e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Neuralized Trypsin_2 PF13365.6 OWF50624.1 - 0.048 14.6 0.6 0.32 11.9 0.6 2.2 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 OWF50624.1 - 0.13 11.4 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Neuralized PF07177.12 OWF50625.1 - 4.6e-10 39.7 0.1 8.6e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Neuralized Lipocalin_2 PF08212.12 OWF50627.1 - 1.5e-12 47.6 0.1 2.1e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF50627.1 - 1.1e-06 28.9 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Transglut_N PF00868.20 OWF50628.1 - 1.5e-29 102.7 0.0 3.8e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 OWF50628.1 - 1.8e-15 57.4 0.1 7.4e-15 55.4 0.2 2.0 3 0 0 3 3 3 1 Transglutaminase-like superfamily Transglut_C PF00927.22 OWF50628.1 - 3.1e-12 46.6 0.0 2.7e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain A2M PF00207.22 OWF50628.1 - 0.00034 20.4 0.0 0.00085 19.1 0.0 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family ABC_tran_2 PF16949.5 OWF50629.1 - 0.0016 17.4 1.3 19 3.9 0.0 5.5 3 2 5 8 8 8 4 Putative ATP-binding cassette Elf1 PF05129.13 OWF50630.1 - 0.00042 20.3 1.1 0.0011 19.0 1.1 1.7 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 OWF50630.1 - 0.39 10.7 3.2 0.94 9.5 3.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain E1_FCCH PF16190.5 OWF50631.1 - 1.7e-12 47.3 31.7 52 4.1 0.1 16.0 1 1 21 22 22 22 21 Ubiquitin-activating enzyme E1 FCCH domain ADH_N_2 PF16884.5 OWF50631.1 - 6.3e-10 38.9 8.2 35 4.3 0.0 9.0 1 1 16 17 17 17 16 N-terminal domain of oxidoreductase P4Ha_N PF08336.11 OWF50632.1 - 0.00068 19.7 4.1 0.9 9.5 0.9 3.4 1 1 2 3 3 3 3 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fib_alpha PF08702.10 OWF50632.1 - 0.056 13.6 1.5 12 6.1 0.2 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family She2p PF11435.8 OWF50632.1 - 0.3 10.7 15.7 4.2 7.0 3.7 3.2 1 1 2 3 3 3 0 RNA binding protein She2p DUF2403 PF10290.9 OWF50633.1 - 3.6 8.1 5.7 45 4.6 0.1 3.1 1 1 2 3 3 3 0 Glycine-rich protein domain (DUF2403) Malic_M PF03949.15 OWF50634.1 - 7.5e-95 317.1 1.2 9.6e-95 316.7 1.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OWF50634.1 - 1.6e-78 262.7 0.0 2.6e-78 262.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Ras PF00071.22 OWF50635.1 - 3.5e-55 186.0 0.0 4.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50635.1 - 1.3e-30 106.0 0.0 1.9e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50635.1 - 5.9e-16 58.4 0.0 7.5e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF50635.1 - 3.7e-06 27.0 0.0 6.9e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF50635.1 - 1.6e-05 24.3 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OWF50635.1 - 0.002 18.1 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 OWF50635.1 - 0.14 11.9 0.0 17 5.2 0.0 2.8 1 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ank_2 PF12796.7 OWF50638.1 - 2.5e-22 79.2 7.1 9.5e-10 38.9 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50638.1 - 4.7e-21 74.9 3.1 2.7e-10 40.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) SAM_1 PF00536.30 OWF50638.1 - 1.8e-17 63.5 0.0 4.2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 OWF50638.1 - 9.3e-15 54.5 3.6 2.3e-08 34.2 0.1 3.6 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50638.1 - 3.1e-13 48.6 6.7 0.0011 19.3 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OWF50638.1 - 5.7e-13 48.7 9.5 0.00032 21.0 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat PDZ_6 PF17820.1 OWF50638.1 - 1.5e-11 44.0 0.3 9.5e-11 41.4 0.2 2.4 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OWF50638.1 - 5e-11 42.8 0.0 1.6e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 OWF50638.1 - 3.2e-10 40.0 0.0 8e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FERM_f0 PF16511.5 OWF50638.1 - 5.5e-07 29.8 0.0 1.7e-06 28.2 0.0 1.9 2 0 0 2 2 1 1 N-terminal or F0 domain of Talin-head FERM SH3_2 PF07653.17 OWF50638.1 - 1.5e-06 27.8 0.3 4.5e-06 26.3 0.3 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF50638.1 - 7.9e-06 25.4 0.1 2.4e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 SH3 domain PDZ_2 PF13180.6 OWF50638.1 - 0.0043 17.4 0.1 0.034 14.5 0.1 2.6 2 0 0 2 2 2 1 PDZ domain Roc PF08477.13 OWF50639.1 - 6e-34 116.8 0.2 3e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF50639.1 - 2.6e-32 111.7 0.1 3.2e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OWF50639.1 - 5.3e-11 42.3 0.0 9.9e-11 41.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF50639.1 - 2e-07 30.6 0.1 2.5e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF50639.1 - 2e-05 24.7 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF50639.1 - 2.2e-05 24.1 0.0 0.00026 20.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OWF50639.1 - 0.00035 20.1 0.0 0.00058 19.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OWF50639.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3460 PF11943.8 OWF50639.1 - 0.07 13.4 0.4 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) TniB PF05621.11 OWF50639.1 - 0.081 12.3 0.0 0.54 9.7 0.0 2.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA_16 PF13191.6 OWF50639.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain COR PF16095.5 OWF50640.1 - 2.5e-14 53.6 1.4 6.6e-14 52.2 0.6 2.1 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 OWF50640.1 - 3.7e-14 53.1 0.0 7.1e-05 23.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Roc PF08477.13 OWF50640.1 - 2.8e-12 46.9 0.0 1.7e-06 28.2 0.1 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ank_4 PF13637.6 OWF50640.1 - 7.3e-08 32.8 0.1 0.0063 17.1 0.1 3.8 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50640.1 - 7.6e-06 25.9 0.1 20 6.1 0.0 5.9 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 OWF50640.1 - 1e-05 25.7 0.8 0.045 14.1 0.1 4.3 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ras PF00071.22 OWF50640.1 - 0.00054 19.6 0.0 0.45 10.1 0.0 2.5 2 0 0 2 2 2 2 Ras family Arf PF00025.21 OWF50640.1 - 0.0033 16.9 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Death PF00531.22 OWF50640.1 - 0.0037 17.4 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 Death domain MMR_HSR1 PF01926.23 OWF50640.1 - 0.0088 16.1 0.0 0.027 14.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OWF50640.1 - 0.09 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OWF50640.1 - 0.098 12.9 0.0 0.73 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arylesterase PF01731.20 OWF50641.1 - 9.4e-14 51.4 0.0 1.9e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 OWF50641.1 - 5.7e-07 29.4 0.0 8.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OWF50641.1 - 6.2e-06 26.3 0.0 1.9e-05 24.7 0.0 1.9 1 1 1 2 2 2 1 Strictosidine synthase SBP56 PF05694.11 OWF50641.1 - 0.094 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Ank_2 PF12796.7 OWF50642.1 - 2.7e-16 59.9 0.2 4.5e-06 27.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Roc PF08477.13 OWF50642.1 - 4.9e-14 52.6 0.0 6.4e-08 32.8 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ank_4 PF13637.6 OWF50642.1 - 3.1e-11 43.6 1.3 0.001 19.6 0.1 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF50642.1 - 2.6e-07 30.8 1.5 0.00025 21.3 0.4 4.1 1 1 4 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50642.1 - 8.5e-07 28.8 0.6 14 6.7 0.0 6.1 6 0 0 6 6 5 0 Ankyrin repeat COR PF16095.5 OWF50642.1 - 9.3e-07 28.9 1.2 4.8e-06 26.5 0.5 2.4 2 1 0 2 2 2 1 C-terminal of Roc, COR, domain Ras PF00071.22 OWF50642.1 - 3.7e-06 26.6 0.0 0.014 15.0 0.1 2.5 2 0 0 2 2 2 2 Ras family Arf PF00025.21 OWF50642.1 - 6.3e-05 22.5 0.1 0.0066 15.9 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Death PF00531.22 OWF50642.1 - 0.00032 20.8 0.1 0.00092 19.3 0.1 1.8 1 0 0 1 1 1 1 Death domain AAA_28 PF13521.6 OWF50642.1 - 0.0027 18.0 0.2 0.019 15.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 OWF50642.1 - 0.013 16.0 0.1 0.086 13.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ank PF00023.30 OWF50642.1 - 0.045 14.2 1.8 15 6.2 0.2 4.4 4 0 0 4 4 4 0 Ankyrin repeat MMR_HSR1 PF01926.23 OWF50642.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 OWF50642.1 - 0.055 13.2 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CUB PF00431.20 OWF50643.1 - 8.1e-14 51.9 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 OWF50643.1 - 0.00029 21.0 14.4 0.00029 21.0 14.4 2.3 2 1 0 2 2 2 1 Low-density lipoprotein receptor domain class A Phage_Gp23 PF10669.9 OWF50643.1 - 0.035 14.4 1.3 0.057 13.8 1.3 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Holin_BhlA PF10960.8 OWF50643.1 - 0.09 12.8 0.0 0.09 12.8 0.0 1.7 2 0 0 2 2 2 0 BhlA holin family FAM176 PF14851.6 OWF50643.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 FAM176 family LapA_dom PF06305.11 OWF50643.1 - 0.63 9.9 2.3 1 9.3 0.4 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain T2SSN PF01203.19 OWF50644.1 - 1.1e-05 25.7 2.4 0.029 14.6 0.6 2.6 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein N Attacin_N PF03768.15 OWF50644.1 - 8.3e-05 22.6 7.9 11 6.3 0.2 7.3 1 1 7 9 9 9 1 Attacin, N-terminal region BBP2_2 PF10082.9 OWF50644.1 - 9.1e-05 21.5 0.4 0.092 11.6 0.2 2.7 1 1 1 2 2 2 2 Putative beta-barrel porin 2 Foamy_BEL PF03274.14 OWF50644.1 - 0.0015 17.9 0.2 15 4.8 0.0 3.7 1 1 3 4 4 4 2 Foamy virus BEL 1/2 protein DUF1794 PF08768.11 OWF50644.1 - 0.0032 17.4 4.2 3.6 7.5 1.6 3.8 1 1 2 3 3 3 1 Domain of unknown function (DUF1794) Propep_M14 PF02244.16 OWF50644.1 - 0.0084 16.5 5.8 3e+02 1.9 5.5 6.1 1 1 0 1 1 1 0 Carboxypeptidase activation peptide DUF3617 PF12276.8 OWF50644.1 - 0.032 14.6 30.1 4.8 7.5 4.5 4.8 1 1 3 5 5 5 0 Protein of unknown function (DUF3617) Exop_C PF18559.1 OWF50644.1 - 0.032 14.1 0.8 35 4.2 0.1 3.6 1 1 2 4 4 4 0 Galactose-binding domain-like DUF745 PF05335.13 OWF50644.1 - 0.32 10.7 0.1 6.7 6.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF5395 PF17373.2 OWF50644.1 - 0.53 10.9 28.2 39 5.0 0.6 8.5 1 1 9 10 10 10 0 Family of unknown function (DUF5395) Kazal_2 PF07648.15 OWF50645.1 - 3.9e-18 65.3 13.3 7e-11 42.1 2.7 3.3 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF50645.1 - 3.7e-13 49.2 21.9 1.3e-08 34.7 5.8 2.8 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain FOLN PF09289.10 OWF50645.1 - 0.0029 17.7 13.0 0.0082 16.3 1.6 2.8 2 0 0 2 2 2 2 Follistatin/Osteonectin-like EGF domain DUF4774 PF15999.5 OWF50646.1 - 0.0047 16.7 0.2 1.9 8.3 0.1 3.6 1 1 3 4 4 4 2 Domain of unknown function (DUF4774) MMtag PF10159.9 OWF50646.1 - 0.059 13.7 1.8 2.7e+02 1.9 0.0 5.0 5 1 1 6 6 6 0 Multiple myeloma tumor-associated DUF3203 PF11462.8 OWF50647.1 - 0.087 13.0 0.2 4.9 7.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3203) YabP PF07873.11 OWF50647.1 - 0.14 11.9 1.9 68 3.4 0.1 4.0 1 1 3 5 5 5 0 YabP family IL5 PF02025.15 OWF50647.1 - 4 7.8 6.8 7.8 6.8 0.6 2.3 1 1 1 2 2 2 0 Interleukin 5 DUF3794 PF12673.7 OWF50648.1 - 0.5 10.7 5.4 72 3.8 0.1 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF3794) Keratin_B2 PF01500.17 OWF50648.1 - 7.2 6.6 16.3 8.1 6.4 3.4 3.7 2 2 2 4 4 4 0 Keratin, high sulfur B2 protein SDF PF00375.18 OWF50649.1 - 2.1e-77 260.8 27.8 2.7e-77 260.4 27.8 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF5528 PF17666.1 OWF50650.1 - 0.0001 22.3 5.5 0.00054 19.9 3.2 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5528) XRCC4 PF06632.12 OWF50651.1 - 6.3e-32 110.8 8.5 7.6e-32 110.5 8.5 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DTHCT PF08070.11 OWF50651.1 - 0.00018 22.2 11.1 0.00018 22.2 11.1 2.8 1 1 1 2 2 2 1 DTHCT (NUC029) region TMEM101 PF15111.6 OWF50652.1 - 2.8e-49 167.9 4.5 3.3e-49 167.7 4.5 1.0 1 0 0 1 1 1 1 TMEM101 protein family SPC12 PF06645.13 OWF50652.1 - 0.0013 18.8 0.8 0.0046 17.0 0.8 2.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) O-antigen_lig PF13425.6 OWF50652.1 - 0.15 10.8 6.6 0.062 12.1 4.1 1.8 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DJ-1_PfpI PF01965.24 OWF50653.1 - 0.00062 19.6 0.0 0.002 17.9 0.0 1.8 2 1 0 2 2 2 1 DJ-1/PfpI family WXG100 PF06013.12 OWF50654.1 - 0.026 14.8 7.0 0.28 11.4 1.4 3.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF812 PF05667.11 OWF50654.1 - 0.095 11.6 5.6 0.11 11.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YadA_head PF05658.14 OWF50654.1 - 0.33 11.4 19.1 0.41 11.1 0.2 6.2 4 2 2 6 6 6 0 Head domain of trimeric autotransporter adhesin DUF3540 PF12059.8 OWF50654.1 - 0.48 10.2 6.2 3.4 7.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) DBD_HTH PF18430.1 OWF50654.1 - 0.64 9.8 12.9 1.1e+02 2.7 0.1 8.3 6 5 1 7 7 7 0 Putative DNA-binding domain SRP-alpha_N PF04086.13 OWF50654.1 - 1.7 8.5 19.1 2 8.2 19.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Draxin PF15550.6 OWF50654.1 - 9.4 6.0 16.1 13 5.5 13.5 1.8 1 1 1 2 2 2 0 Draxin DUF2059 PF09832.9 OWF50654.1 - 9.6 6.4 7.7 25 5.0 0.7 3.1 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2059) Astro_capsid_N PF03115.14 OWF50656.1 - 0.032 12.9 0.0 0.033 12.8 0.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Guanylate_cyc PF00211.20 OWF50658.1 - 6.1e-64 215.0 0.1 1.2e-63 214.0 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF50658.1 - 4.5e-36 124.4 0.0 1.2e-35 123.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF50658.1 - 2.4e-30 105.8 0.0 4.4e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 OWF50658.1 - 2.8e-15 56.3 0.0 5.5e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 OWF50658.1 - 9.2e-07 28.5 2.1 1.5e-06 27.8 2.1 1.3 1 0 0 1 1 1 1 Heme NO binding associated MazE_antitoxin PF04014.18 OWF50660.1 - 5.8e-07 29.3 9.6 8.7 6.4 0.0 8.3 9 0 0 9 9 9 3 Antidote-toxin recognition MazE, bacterial antitoxin RuvB_C PF05491.13 OWF50660.1 - 0.035 14.0 3.4 6.2 6.8 0.0 4.6 3 2 3 6 6 6 0 RuvB C-terminal winged helix domain DUF4957 PF16318.5 OWF50660.1 - 1.9 8.4 28.2 1.4 8.9 0.3 5.1 3 2 1 4 4 4 0 Domain of unknown function (DUF4957) TYA PF01021.19 OWF50660.1 - 7.4 7.0 13.2 42 4.5 0.1 4.7 3 2 2 5 5 5 0 TYA transposon protein PXT1 PF15214.6 OWF50662.1 - 0.066 13.6 3.7 1.2 9.6 0.6 2.6 1 1 1 2 2 2 0 Peroxisomal testis-specific protein 1 DUF3918 PF13056.6 OWF50662.1 - 0.11 12.1 2.9 3 7.5 0.2 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3918) Ion_trans PF00520.31 OWF50663.1 - 0.00027 20.2 0.3 0.00043 19.6 0.3 1.3 1 0 0 1 1 1 1 Ion transport protein DUF853 PF05872.12 OWF50664.1 - 0.13 10.8 0.4 0.21 10.1 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MFS_1 PF07690.16 OWF50665.1 - 7.7e-17 61.2 27.7 9.6e-14 51.1 18.5 3.6 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OWF50665.1 - 7.8e-17 60.9 21.3 2.8e-12 45.9 2.6 3.6 4 0 0 4 4 4 3 MFS/sugar transport protein PUCC PF03209.15 OWF50665.1 - 0.011 14.8 0.4 0.011 14.8 0.4 2.7 3 0 0 3 3 3 0 PUCC protein PHD PF00628.29 OWF50666.1 - 7.1e-10 38.6 8.7 1.3e-09 37.8 8.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OWF50666.1 - 0.013 15.8 0.1 0.041 14.1 0.1 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 OWF50666.1 - 0.034 14.2 1.7 0.034 14.2 1.7 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger AT_hook PF02178.19 OWF50666.1 - 0.11 12.5 6.5 0.34 10.9 6.5 2.0 1 0 0 1 1 1 0 AT hook motif PHD_2 PF13831.6 OWF50666.1 - 0.6 9.7 3.9 1.4 8.6 3.9 1.6 1 0 0 1 1 1 0 PHD-finger Syntaxin_2 PF14523.6 OWF50666.1 - 0.69 10.3 12.3 0.2 12.0 1.4 2.6 2 0 0 2 2 2 0 Syntaxin-like protein DUF4164 PF13747.6 OWF50666.1 - 1.1 9.6 7.9 0.65 10.3 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ADIP PF11559.8 OWF50666.1 - 1.2 9.2 18.7 0.43 10.7 7.3 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding C1_1 PF00130.22 OWF50666.1 - 2.7 7.9 7.3 0.12 12.2 1.3 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 OWF50666.1 - 4.3 7.4 13.0 9.9 6.2 0.5 4.2 4 0 0 4 4 4 0 Adenylate kinase, active site lid GNT-I PF03071.15 OWF50666.1 - 5.1 5.8 6.7 0.5 9.1 2.3 1.5 2 0 0 2 2 2 0 GNT-I family Prok-RING_1 PF14446.6 OWF50666.1 - 6.9 6.7 9.2 1.9 8.5 4.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 OWF50666.1 - 9.6 5.8 11.1 0.25 10.9 2.6 2.5 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain NUP50 PF08911.11 OWF50667.1 - 6.6e-18 65.1 3.2 6.6e-18 65.1 3.2 3.1 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 OWF50667.1 - 1e-10 41.9 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain PDZ PF00595.24 OWF50668.1 - 1.1e-40 137.8 10.4 8.5e-13 48.5 0.1 4.5 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 OWF50668.1 - 2e-35 120.4 13.5 1.2e-12 47.5 0.3 3.7 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 OWF50668.1 - 1.2e-22 80.0 14.7 1.6e-07 31.5 0.2 4.7 4 1 1 5 5 5 3 PDZ domain Tricorn_PDZ PF14685.6 OWF50668.1 - 1.3e-06 28.2 6.3 0.26 11.3 0.1 3.5 3 0 0 3 3 3 3 Tricorn protease PDZ domain Amidase_6 PF12671.7 OWF50668.1 - 0.0017 18.5 2.3 3.8 7.6 0.1 3.2 3 0 0 3 3 3 2 Putative amidase domain DWNN PF08783.11 OWF50668.1 - 0.46 10.8 3.1 7.3 7.0 0.1 2.7 3 0 0 3 3 3 0 DWNN domain Mitofilin PF09731.9 OWF50668.1 - 4.1 6.1 12.4 8.6 5.1 12.4 1.5 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Vps39_2 PF10367.9 OWF50669.1 - 5.9e-26 91.1 0.8 5.9e-26 91.1 0.8 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OWF50669.1 - 8.8e-20 71.4 0.9 1.2e-19 71.0 0.1 1.6 2 0 0 2 2 2 1 CNH domain Vps39_1 PF10366.9 OWF50669.1 - 1.5e-16 60.6 4.5 4.5e-13 49.4 0.1 3.6 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 OWF50669.1 - 1.1e-15 57.8 9.5 9.9e-10 38.5 3.3 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS HTH_10 PF04967.12 OWF50670.1 - 1.1e-09 37.9 0.5 19 5.2 0.0 7.7 7 1 1 8 8 8 1 HTH DNA binding domain MALT1_Ig PF18703.1 OWF50670.1 - 7.4e-07 29.3 32.4 2.4 8.2 0.6 7.8 1 1 7 8 8 8 7 MALT1 Ig-like domain NADH-G_4Fe-4S_3 PF10588.9 OWF50670.1 - 8.9e-07 28.4 7.2 19 4.9 0.0 7.2 7 0 0 7 7 7 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Arylesterase PF01731.20 OWF50670.1 - 0.0062 16.7 20.5 22 5.3 0.0 7.9 7 2 1 9 9 9 1 Arylesterase DUF2642 PF10842.8 OWF50670.1 - 0.055 13.3 7.8 1.4e+02 2.4 0.0 6.5 7 0 0 7 7 7 0 Protein of unknown function (DUF2642) HCV_NS5a_1b PF08301.13 OWF50670.1 - 0.098 13.2 20.8 29 5.3 0.1 7.4 1 1 7 8 8 8 0 Hepatitis C virus non-structural 5a domain 1b ENT PF03735.14 OWF50670.1 - 1.4 9.1 13.7 13 5.9 0.1 5.3 3 3 4 7 7 7 0 ENT domain SSB PF00436.25 OWF50671.1 - 8.3e-19 67.6 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family CdiI_2 PF18593.1 OWF50672.1 - 0.088 13.5 0.0 5 7.9 0.0 2.2 2 0 0 2 2 2 0 CdiI immunity protein PAP2 PF01569.21 OWF50673.1 - 3.4e-28 98.1 4.0 6.6e-28 97.2 4.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OWF50673.1 - 1.7e-05 25.3 4.2 5.7e-05 23.6 4.2 1.9 1 0 0 1 1 1 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 OWF50673.1 - 0.00016 21.4 2.5 0.00016 21.4 2.5 2.2 1 1 1 2 2 2 1 PAP2 superfamily DUF996 PF06195.13 OWF50673.1 - 0.0059 16.9 0.2 0.063 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF996) Phage_holin_3_1 PF05106.12 OWF50673.1 - 0.024 15.1 0.5 0.048 14.1 0.1 1.7 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) YfhO PF09586.10 OWF50673.1 - 0.049 11.9 3.8 0.067 11.4 3.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2070 PF09843.9 OWF50673.1 - 1.4 7.2 5.8 0.12 10.7 1.4 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) HKR_ArcB_TM PF18415.1 OWF50673.1 - 7.9 7.4 7.6 0.54 11.1 1.2 2.4 2 1 1 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain EVE PF01878.18 OWF50674.1 - 1.6e-46 157.9 0.0 2e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 EVE domain LRR_4 PF12799.7 OWF50675.1 - 2.3e-11 43.7 16.6 6.6e-08 32.7 2.8 3.7 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF50675.1 - 2.6e-08 33.6 0.1 5.2e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OWF50675.1 - 1.9e-06 27.5 1.7 1.9e-06 27.5 1.7 3.2 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 OWF50675.1 - 0.0018 18.1 1.1 0.89 9.8 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeat LRR_1 PF00560.33 OWF50675.1 - 0.14 12.8 9.6 7.1 7.6 0.1 4.4 4 1 1 5 5 5 0 Leucine Rich Repeat Tetraspanin PF00335.20 OWF50676.1 - 1.8e-45 155.5 15.7 2.2e-45 155.1 15.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2301 PF10063.9 OWF50676.1 - 0.18 12.2 3.7 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) DUF2304 PF10066.9 OWF50676.1 - 2.5 8.4 9.6 3.2 8.0 1.3 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2304) Reprolysin PF01421.19 OWF50677.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Methyltransf_FA PF12248.8 OWF50678.1 - 6.1e-23 81.1 0.3 2.8e-22 79.0 0.1 2.3 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase DCX PF03607.17 OWF50678.1 - 1.2e-13 51.0 0.0 0.084 13.0 0.0 6.4 6 0 0 6 6 6 4 Doublecortin Ricin_B_lectin PF00652.22 OWF50678.1 - 7.5e-08 32.7 2.2 0.0076 16.5 0.0 3.9 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain KHA PF11834.8 OWF50678.1 - 5.5e-05 23.2 0.0 0.35 11.0 0.0 3.8 3 0 0 3 3 3 1 KHA, dimerisation domain of potassium ion channel Arc_PepC_II PF06847.11 OWF50678.1 - 0.0084 16.6 0.2 0.67 10.5 0.0 3.9 4 0 0 4 4 4 1 Archaeal Peptidase A24 C-terminus Type II Myc_N PF01056.18 OWF50678.1 - 0.073 13.0 2.6 0.22 11.4 2.6 1.8 1 0 0 1 1 1 0 Myc amino-terminal region Adaptin_N PF01602.20 OWF50679.1 - 5.2e-146 487.3 4.4 6.3e-146 487.0 4.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OWF50679.1 - 8e-37 125.9 0.0 1.9e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OWF50679.1 - 5.4e-18 65.3 0.7 1.4e-17 64.0 0.7 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OWF50679.1 - 1.7e-05 24.9 0.5 0.00045 20.3 0.0 2.7 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OWF50679.1 - 0.0012 19.2 4.2 0.23 11.9 0.1 4.3 3 2 1 5 5 5 1 HEAT repeats HEAT PF02985.22 OWF50679.1 - 0.0036 17.4 4.9 42 4.8 0.0 6.2 6 1 1 7 7 7 0 HEAT repeat B2-adapt-app_C PF09066.10 OWF50679.1 - 0.056 13.5 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain RIX1 PF08167.12 OWF50679.1 - 0.085 12.6 2.4 2 8.1 0.5 3.5 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Ribosomal_S26e PF01283.19 OWF50680.1 - 2.8e-09 37.4 35.5 15 6.0 0.0 22.9 2 1 36 38 38 38 1 Ribosomal protein S26e NAC PF01849.18 OWF50681.1 - 0.00047 20.1 19.8 17 5.5 0.1 8.3 1 1 6 7 7 7 2 NAC domain ZipA_C PF04354.13 OWF50681.1 - 0.06 13.2 9.8 1.8 8.4 0.2 3.9 1 1 3 4 4 4 0 ZipA, C-terminal FtsZ-binding domain DUF2649 PF10854.8 OWF50681.1 - 0.092 13.1 0.8 73 3.8 0.0 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF2649) LAT PF15234.6 OWF50681.1 - 0.89 9.2 7.5 3.7e+02 0.7 7.5 3.1 1 1 0 1 1 1 0 Linker for activation of T-cells DUF1743 PF08489.11 OWF50681.1 - 3 7.9 9.2 8.3 6.5 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1743) IL4Ra_N PF09238.10 OWF50686.1 - 0.024 14.9 15.1 0.024 14.9 15.1 2.1 1 1 1 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal Peptidase_C2 PF00648.21 OWF50689.1 - 7.1e-92 307.6 0.0 1e-91 307.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF50689.1 - 5e-22 78.7 0.0 2.6e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_8 PF13833.6 OWF50689.1 - 0.035 14.0 0.0 0.95 9.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 OWF50689.1 - 0.093 12.3 0.0 0.28 10.8 0.0 1.9 1 0 0 1 1 1 0 EF hand Tetraspanin PF00335.20 OWF50690.1 - 6.8e-42 143.7 19.1 8.3e-42 143.4 19.1 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2157 PF09925.9 OWF50690.1 - 2.4e-05 24.2 0.0 0.0069 16.2 0.0 2.4 1 1 1 2 2 2 2 Predicted membrane protein (DUF2157) DUF2981 PF11200.8 OWF50690.1 - 0.081 12.7 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) MLANA PF14991.6 OWF50690.1 - 0.49 10.7 0.1 0.49 10.7 0.1 3.3 2 1 2 4 4 4 0 Protein melan-A MIG-14_Wnt-bd PF06664.12 OWF50690.1 - 2.7 7.1 8.8 0.48 9.6 1.9 2.0 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion MacB_PCD PF12704.7 OWF50690.1 - 6 7.2 10.7 5.6 7.3 0.0 2.4 2 0 0 2 2 2 0 MacB-like periplasmic core domain ANF_receptor PF01094.28 OWF50691.1 - 3.6e-41 141.5 0.2 4.7e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF50691.1 - 8.4e-07 29.0 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DUF3425 PF11905.8 OWF50691.1 - 0.13 12.3 0.1 0.76 9.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) Guanylate_cyc PF00211.20 OWF50692.1 - 1e-65 220.8 0.0 1.8e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF50692.1 - 3.6e-35 121.5 0.0 5.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF50692.1 - 5.1e-32 111.3 0.0 1.1e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF50692.1 - 2.2e-05 24.0 0.5 4.3e-05 23.0 0.5 1.5 1 0 0 1 1 1 1 Heme NO binding associated Dynein_AAA_lid PF17852.1 OWF50692.1 - 0.043 13.9 0.1 6 7.0 0.1 2.6 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain Aldo_ket_red PF00248.21 OWF50693.1 - 1.3e-37 129.6 0.0 4.9e-29 101.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family MAGUK_N_PEST PF10608.9 OWF50694.1 - 0.015 15.7 0.6 10 6.6 1.0 2.4 2 1 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK DUF2492 PF10678.9 OWF50694.1 - 1.4 9.3 6.4 1.1e+02 3.2 0.0 4.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2492) DGF-1_4 PF11024.8 OWF50694.1 - 1.9 9.4 10.2 12 6.8 0.1 3.2 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 ApoL PF05461.11 OWF50696.1 - 0.44 9.8 12.8 3.1 7.0 12.8 2.0 1 1 0 1 1 1 0 Apolipoprotein L PLAC8 PF04749.17 OWF50697.1 - 1.8e-19 70.5 9.3 2.1e-19 70.3 9.3 1.0 1 0 0 1 1 1 1 PLAC8 family Lipase_GDSL_2 PF13472.6 OWF50698.1 - 0.095 13.1 0.1 0.23 11.8 0.1 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Galactosyl_T PF01762.21 OWF50699.1 - 1.3e-47 162.2 2.0 1.5e-47 162.0 2.0 1.0 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF50699.1 - 6.6e-06 25.7 0.1 8.3e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Fringe-like Focal_AT PF03623.13 OWF50699.1 - 0.019 14.9 0.4 4 7.4 0.1 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region ERM PF00769.19 OWF50700.1 - 0.0076 16.1 54.8 0.012 15.4 42.4 2.3 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Macoilin PF09726.9 OWF50700.1 - 0.0084 14.7 28.2 0.012 14.2 28.2 1.2 1 0 0 1 1 1 1 Macoilin family APG6_N PF17675.1 OWF50700.1 - 0.051 14.1 57.3 25 5.4 1.0 3.6 1 1 1 3 3 3 0 Apg6 coiled-coil region DUF3450 PF11932.8 OWF50700.1 - 0.15 11.3 39.0 3.5 6.9 22.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 OWF50700.1 - 0.18 10.7 49.0 0.14 11.0 33.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 OWF50700.1 - 0.31 10.6 38.1 0.92 9.0 13.1 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit SOBP PF15279.6 OWF50700.1 - 0.69 10.5 11.0 1 9.9 11.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GAS PF13851.6 OWF50700.1 - 2.5 7.4 48.4 0.54 9.6 38.5 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 OWF50700.1 - 8.7 6.1 54.6 22 4.8 25.7 3.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH PurA PF04845.13 OWF50701.1 - 4.7e-98 326.9 0.0 5.4e-98 326.7 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 OWF50701.1 - 3.4e-06 27.2 0.8 1 9.5 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3276) EFG_C PF00679.24 OWF50701.1 - 0.017 15.1 0.1 14 5.8 0.0 3.0 3 0 0 3 3 3 0 Elongation factor G C-terminus DUF5109 PF17134.4 OWF50702.1 - 0.21 11.5 0.3 0.46 10.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) G_glu_transpept PF01019.21 OWF50703.1 - 1.5e-150 502.3 0.0 1.9e-150 502.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DERM PF14704.6 OWF50704.1 - 0.00018 22.0 0.1 0.00082 19.9 0.0 1.9 1 1 1 2 2 2 1 Dermatopontin Hormone_recep PF00104.30 OWF50705.1 - 0.035 13.7 0.3 0.86 9.1 0.0 2.2 1 1 1 2 2 2 0 Ligand-binding domain of nuclear hormone receptor G_glu_transpept PF01019.21 OWF50706.1 - 3.3e-145 484.8 0.0 3.8e-145 484.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ion_trans PF00520.31 OWF50707.1 - 3.2e-41 141.2 15.7 4.1e-41 140.8 15.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF50707.1 - 2.9e-29 101.3 0.0 5.7e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF50707.1 - 2.9e-09 36.8 6.4 2.9e-09 36.8 6.4 2.7 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 OWF50707.1 - 0.0035 17.4 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TM140 PF14985.6 OWF50707.1 - 0.014 14.9 0.3 0.028 14.0 0.3 1.4 1 0 0 1 1 1 0 TM140 protein family PKD_channel PF08016.12 OWF50707.1 - 1.4 7.5 9.9 0.29 9.8 2.9 2.1 1 1 1 2 2 2 0 Polycystin cation channel EF-hand_1 PF00036.32 OWF50708.1 - 1.7e-11 42.8 5.4 6.7e-06 25.3 0.4 3.3 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 OWF50708.1 - 2e-10 39.8 3.6 0.00017 21.2 0.3 3.4 2 1 1 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 OWF50708.1 - 1.7e-07 31.5 5.4 4.6e-06 27.0 5.2 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF50708.1 - 1.4e-06 27.6 1.4 0.0002 20.7 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 OWF50708.1 - 0.0005 19.9 0.6 0.035 14.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF50708.1 - 0.012 16.0 0.9 3.5 8.0 0.0 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PDZ PF00595.24 OWF50709.1 - 9.4e-14 51.5 0.0 1e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF50709.1 - 0.00039 20.7 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF50709.1 - 0.06 13.2 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 PDZ domain Cpn10 PF00166.21 OWF50710.1 - 4.4e-11 42.7 37.3 0.098 12.7 0.7 9.8 1 1 6 7 7 7 5 Chaperonin 10 Kd subunit Glyco_hydro_65C PF03633.15 OWF50710.1 - 1.6e-09 37.6 25.2 0.38 10.7 0.7 9.2 3 3 4 9 9 9 2 Glycosyl hydrolase family 65, C-terminal domain C1q PF00386.21 OWF50710.1 - 1.6e-09 38.1 2.5 0.71 10.1 0.2 6.3 1 1 7 8 8 8 3 C1q domain Poly_export PF02563.16 OWF50710.1 - 1.3e-08 35.0 23.1 1.2e+02 3.0 0.0 9.9 1 1 1 2 2 1 0 Polysaccharide biosynthesis/export protein TOBE_2 PF08402.10 OWF50710.1 - 1.2e-07 31.7 6.5 0.23 11.6 0.2 6.4 1 1 6 8 8 8 3 TOBE domain GcnA_N PF18229.1 OWF50710.1 - 2.2e-06 27.6 14.6 23 5.1 0.0 9.2 2 2 4 7 7 7 0 N-acetyl-beta-D-glucosaminidase N-terminal domain DUF5599 PF18141.1 OWF50710.1 - 3.7e-06 27.1 20.5 3.6 7.9 1.1 7.6 1 1 2 4 4 4 2 Domain of unknown function (DUF5599) PBP5_C PF07943.13 OWF50710.1 - 3e-05 24.2 33.2 0.57 10.5 5.3 6.1 1 1 4 6 6 6 3 Penicillin-binding protein 5, C-terminal domain CusF_Ec PF11604.8 OWF50710.1 - 0.00017 21.5 31.0 14 5.7 1.0 10.6 2 2 9 13 13 13 0 Copper binding periplasmic protein CusF Cupredoxin_1 PF13473.6 OWF50710.1 - 0.00017 21.6 26.8 7.1 6.8 0.5 8.5 1 1 5 6 6 6 0 Cupredoxin-like domain TOBE PF03459.17 OWF50710.1 - 0.0002 21.6 1.5 46 4.4 0.0 6.5 2 2 7 9 9 9 0 TOBE domain VWD PF00094.25 OWF50710.1 - 0.00039 20.7 16.4 0.95 9.7 0.3 4.1 1 1 2 3 3 3 2 von Willebrand factor type D domain DUF4251 PF14059.6 OWF50710.1 - 0.0013 18.6 12.2 7.6 6.5 5.0 5.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4251) M60-like_N PF17291.2 OWF50710.1 - 0.0057 16.5 15.3 4.7 7.1 2.0 5.5 1 1 3 4 4 4 1 N-terminal domain of M60-like peptidases DUF2917 PF11142.8 OWF50710.1 - 0.0073 15.7 3.8 20 4.6 0.0 6.8 4 2 4 9 9 9 0 Protein of unknown function (DUF2917) CLP1_N PF16573.5 OWF50710.1 - 0.044 14.0 9.5 1.1e+02 3.1 0.3 7.5 2 2 6 9 9 9 0 N-terminal beta-sandwich domain of polyadenylation factor FixG_C PF11614.8 OWF50710.1 - 0.053 13.7 16.6 1.6e+02 2.6 6.7 5.0 1 1 1 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase OapA PF04225.12 OWF50710.1 - 0.06 13.5 37.3 5.7 7.1 1.5 8.7 1 1 8 9 9 9 0 Opacity-associated protein A LysM-like domain Arch_flagellin PF01917.16 OWF50710.1 - 0.079 13.1 5.5 1.2e+02 2.8 5.5 4.3 1 1 0 1 1 1 0 Archaebacterial flagellin PmbA_TldD PF01523.16 OWF50710.1 - 0.1 12.4 30.7 0.47 10.2 1.5 5.4 1 1 5 6 6 6 0 Putative modulator of DNA gyrase Alpha-amylase_N PF02903.14 OWF50710.1 - 0.39 10.9 31.1 23 5.2 0.2 8.3 1 1 4 6 6 6 0 Alpha amylase, N-terminal ig-like domain DUF1857 PF08982.11 OWF50710.1 - 0.46 10.3 3.4 1.7e+02 2.0 2.8 4.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1857) zf-ZPR1 PF03367.13 OWF50710.1 - 0.94 9.3 22.0 22 4.9 0.3 6.1 1 1 7 8 8 8 0 ZPR1 zinc-finger domain EspG PF06872.11 OWF50710.1 - 2.1 6.8 15.2 26 3.2 0.1 5.4 1 1 5 7 7 7 0 EspG protein Laminin_G_1 PF00054.23 OWF50710.1 - 3.7 7.8 17.6 22 5.3 0.9 4.9 1 1 3 4 4 4 0 Laminin G domain Myosin_N PF02736.19 OWF50710.1 - 5.5 6.9 56.2 0.77 9.7 0.5 11.0 3 2 12 16 16 16 0 Myosin N-terminal SH3-like domain Cornifin PF02389.15 OWF50711.1 - 0.14 12.3 0.3 0.22 11.7 0.3 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family CNOT11 PF10155.9 OWF50712.1 - 6e-54 181.5 6.9 1.2e-53 180.5 6.9 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 RIC3 PF15361.6 OWF50713.1 - 5.8e-28 98.1 0.2 5.8e-28 98.1 0.2 2.6 2 2 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 SARAF PF06682.12 OWF50713.1 - 0.49 10.0 10.6 1.9 8.1 9.1 2.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis AA_permease_N PF08403.10 OWF50714.1 - 4e-05 23.0 0.0 6 6.4 0.0 5.9 4 2 1 5 5 5 1 Amino acid permease N-terminal B1 PF02246.15 OWF50714.1 - 7.7e-05 22.7 1.1 38 4.4 0.0 5.4 3 1 4 7 7 7 0 Protein L b1 domain DUF452 PF04301.13 OWF50714.1 - 0.00012 21.7 11.5 6.9 6.1 0.0 6.5 1 1 4 6 6 6 1 Protein of unknown function (DUF452) ApoLp-III PF07464.11 OWF50714.1 - 0.00021 21.4 0.3 0.00075 19.6 0.2 1.8 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.21 OWF50714.1 - 0.00074 19.4 1.5 0.0051 16.6 1.0 2.6 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.11 OWF50714.1 - 0.0065 14.5 3.6 0.0084 14.1 3.6 1.2 1 0 0 1 1 1 1 Prominin LIN52 PF10044.9 OWF50714.1 - 0.0071 17.0 0.5 5.9 7.7 0.1 3.5 1 1 2 3 3 3 1 Retinal tissue protein PmrD PF11183.8 OWF50714.1 - 0.018 15.2 0.7 78 3.5 0.0 4.8 4 1 0 5 5 5 0 Polymyxin resistance protein PmrD Ribosomal_L11 PF00298.19 OWF50714.1 - 0.023 15.2 0.0 22 5.6 0.0 4.4 4 1 1 6 6 6 0 Ribosomal protein L11, RNA binding domain DUF3275 PF11679.8 OWF50714.1 - 0.033 14.2 1.6 0.18 11.8 0.1 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3275) Toxin_15 PF07906.13 OWF50714.1 - 0.068 12.7 1.7 0.12 11.9 1.7 1.4 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region DUF4242 PF14026.6 OWF50714.1 - 0.11 12.7 9.8 12 6.1 0.1 5.2 2 1 4 7 7 7 0 Protein of unknown function (DUF4242) DUF1833 PF08875.11 OWF50714.1 - 0.77 9.3 4.2 27 4.3 1.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1833) PAN_2 PF08276.11 OWF50714.1 - 0.96 9.6 25.3 65 3.8 0.2 8.5 5 2 5 10 10 10 0 PAN-like domain PH_BEACH PF14844.6 OWF50714.1 - 1.3 9.2 11.9 30 4.8 0.1 6.2 2 1 4 7 7 7 0 PH domain associated with Beige/BEACH Bromodomain PF00439.25 OWF50716.1 - 6.2e-16 58.3 0.0 1.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain EMP24_GP25L PF01105.24 OWF50717.1 - 2.6e-40 138.3 0.9 3e-40 138.1 0.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4698 PF15769.5 OWF50717.1 - 0.049 12.7 0.2 0.059 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Spt5_N PF11942.8 OWF50717.1 - 0.078 14.0 4.2 0.12 13.3 4.2 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4589 PF15252.6 OWF50717.1 - 0.21 11.5 0.8 0.31 11.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) CD225 PF04505.12 OWF50718.1 - 0.07 13.3 0.5 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Leader_CPA1 PF08252.11 OWF50719.1 - 0.0024 17.2 4.2 41 3.7 0.0 6.4 8 0 0 8 8 8 1 arg-2/CPA1 leader peptide Drf_FH1 PF06346.12 OWF50719.1 - 0.07 12.9 1.8 0.46 10.2 1.8 2.1 1 1 0 1 1 1 0 Formin Homology Region 1 DUF4841 PF16129.5 OWF50719.1 - 1 9.6 3.3 92 3.4 0.0 3.9 3 2 1 5 5 5 0 Domain of unknown function (DUF4841) Usp PF00582.26 OWF50720.1 - 0.045 14.3 11.7 12 6.4 0.2 4.6 1 1 3 5 5 5 0 Universal stress protein family SCP_3 PF17844.1 OWF50720.1 - 0.13 12.1 0.0 0.83 9.5 0.0 2.2 1 1 0 2 2 2 0 Bacterial SCP ortholog DUF4033 PF13225.6 OWF50721.1 - 0.36 10.9 11.0 0.86 9.6 0.5 4.1 2 1 3 5 5 5 0 Domain of unknown function (DUF4033) DUF4797 PF16051.5 OWF50722.1 - 0.063 13.2 37.9 1.1e+02 2.9 0.6 13.5 2 2 12 14 14 14 0 Domain of unknown function (DUF4797) PCC_BT PF18140.1 OWF50723.1 - 0.015 15.7 7.9 3.2 8.1 0.2 4.2 1 1 3 4 4 4 0 Propionyl-coenzyme A carboxylase BT domain LRR_5 PF13306.6 OWF50723.1 - 0.091 12.7 13.0 9.2 6.2 0.2 3.4 1 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Mucin-like PF16058.5 OWF50724.1 - 4.5e-06 26.7 2.7 0.0014 18.7 2.6 2.5 1 1 1 2 2 2 2 Mucin-like DUF4376 PF14301.6 OWF50724.1 - 0.12 12.8 10.8 1.3e+02 3.0 0.0 6.3 2 1 8 10 10 10 0 Domain of unknown function (DUF4376) SBF2 PF12335.8 OWF50724.1 - 0.19 11.3 31.5 1.3 8.6 2.2 4.2 1 1 3 4 4 4 0 Myotubularin protein FIVAR PF07554.13 OWF50724.1 - 0.36 11.6 26.8 1.1e+02 3.7 1.9 7.5 1 1 3 4 4 4 0 FIVAR domain HALZ PF02183.18 OWF50724.1 - 2.8 8.2 24.0 69 3.8 0.3 8.6 3 1 7 10 10 10 0 Homeobox associated leucine zipper DUF883 PF05957.13 OWF50724.1 - 6.8 7.4 29.8 3.9 8.2 2.2 4.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) MyTH4 PF00784.17 OWF50725.1 - 4.1e-31 107.7 3.6 4.1e-31 107.7 3.6 3.6 3 1 0 3 3 2 1 MyTH4 domain PH PF00169.29 OWF50725.1 - 2.7e-27 95.3 2.1 5.7e-15 55.7 1.2 2.9 2 0 0 2 2 2 2 PH domain FERM_M PF00373.18 OWF50725.1 - 8.6e-11 42.3 0.0 8.6e-11 42.3 0.0 2.9 3 1 1 4 4 1 1 FERM central domain PH_3 PF14593.6 OWF50725.1 - 1.5e-07 31.5 3.8 2.7e-06 27.4 1.7 3.3 2 1 1 3 3 3 1 PH domain PH_11 PF15413.6 OWF50725.1 - 1.6e-07 31.7 8.2 1.6e-06 28.5 5.4 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 OWF50725.1 - 0.00068 19.9 0.0 0.01 16.1 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain V_ATPase_I PF01496.19 OWF50725.1 - 0.00084 17.4 8.8 0.0015 16.6 8.8 1.4 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HMMR_N PF15905.5 OWF50725.1 - 0.0039 16.7 24.7 0.0094 15.5 24.7 1.6 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Tropomyosin PF00261.20 OWF50725.1 - 0.0039 16.6 23.3 0.01 15.2 23.3 1.6 1 0 0 1 1 1 1 Tropomyosin MscS_porin PF12795.7 OWF50725.1 - 0.015 14.8 25.6 0.036 13.6 25.6 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain FERM_C PF09380.10 OWF50725.1 - 0.067 13.6 0.1 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 FERM C-terminal PH-like domain YfdX PF10938.8 OWF50725.1 - 0.16 11.9 4.6 0.33 10.9 4.6 1.5 1 0 0 1 1 1 0 YfdX protein HALZ PF02183.18 OWF50725.1 - 0.17 12.1 3.7 0.76 10.1 3.7 2.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper CEP63 PF17045.5 OWF50725.1 - 0.19 11.6 26.4 0.5 10.2 26.4 1.6 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Tropomyosin_1 PF12718.7 OWF50725.1 - 0.25 11.5 28.5 3.1 7.9 4.4 3.5 1 1 2 3 3 3 0 Tropomyosin like ApoO PF09769.9 OWF50725.1 - 0.26 11.3 9.6 1 9.3 0.2 3.2 3 0 0 3 3 3 0 Apolipoprotein O Sec3-PIP2_bind PF15277.6 OWF50725.1 - 0.28 11.3 2.2 0.96 9.6 0.1 3.0 3 0 0 3 3 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF4686 PF15742.5 OWF50725.1 - 0.44 9.6 32.2 0.78 8.8 32.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF3584 PF12128.8 OWF50725.1 - 0.53 7.7 23.0 0.82 7.1 23.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 OWF50725.1 - 0.64 9.4 27.5 0.28 10.6 23.8 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 OWF50725.1 - 0.88 8.4 29.1 3.7 6.3 29.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein VPS38 PF17649.1 OWF50725.1 - 1.7 7.4 12.0 2.5 6.9 11.4 1.5 1 1 0 1 1 1 0 Vacuolar protein sorting 38 Exonuc_VII_L PF02601.15 OWF50725.1 - 2 7.9 16.5 5.8 6.4 16.5 1.8 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 OWF50725.1 - 4.5 7.4 19.6 1.8 8.7 3.3 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TSC22 PF01166.18 OWF50725.1 - 5.3 7.4 10.2 3 8.2 0.6 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family Laminin_II PF06009.12 OWF50725.1 - 5.6 7.0 18.2 1.9 8.5 1.3 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 OWF50725.1 - 7.4 6.6 20.1 0.16 12.0 2.1 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF2428 PF10350.9 OWF50726.1 - 1.1e-79 267.5 0.0 3.3e-79 266.0 0.0 1.9 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) Arm PF00514.23 OWF50726.1 - 0.082 13.0 0.4 0.58 10.3 0.1 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CHASE4 PF05228.13 OWF50726.1 - 0.29 11.3 1.0 39 4.4 0.0 2.9 3 0 0 3 3 3 0 CHASE4 domain HEAT PF02985.22 OWF50726.1 - 6.6 7.3 11.2 28 5.3 0.0 5.6 7 0 0 7 7 7 0 HEAT repeat Fibrinogen_BP PF08017.11 OWF50728.1 - 5.6e-40 137.0 12.4 1.1e-21 76.8 1.5 2.0 1 1 1 2 2 2 2 Fibrinogen binding protein zf-CCCH PF00642.24 OWF50730.1 - 1.4e-21 75.9 17.9 1.1e-10 41.1 4.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF50730.1 - 5.3e-11 42.2 16.7 3.6e-06 26.9 4.1 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OWF50730.1 - 2.5e-05 23.9 15.1 0.0011 18.7 2.6 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger Tis11B_N PF04553.12 OWF50730.1 - 5.9e-05 23.6 0.2 5.9e-05 23.6 0.2 2.7 2 2 0 2 2 2 1 Tis11B like protein, N terminus zf-CCCH_2 PF14608.6 OWF50730.1 - 0.078 13.5 18.9 0.15 12.6 2.1 2.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OWF50730.1 - 0.082 13.6 9.5 2.6 8.8 2.0 2.8 1 1 0 2 2 2 0 Torus domain oligo_HPY PF08352.12 OWF50730.1 - 0.25 11.9 3.4 7.8 7.1 0.4 2.8 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region DUF411 PF04214.13 OWF50731.1 - 0.00057 19.8 12.7 5.9 6.9 0.0 6.5 3 2 4 7 7 7 3 Protein of unknown function, DUF Pox_polyA_pol PF03296.13 OWF50731.1 - 0.19 11.6 11.8 6.1 6.7 0.2 4.0 1 1 3 4 4 4 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain DUF488 PF04343.13 OWF50731.1 - 0.49 11.0 1.6 1.1e+02 3.4 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function, DUF488 Photo_RC PF00124.19 OWF50731.1 - 3.8 6.7 8.8 4.2 6.5 0.3 3.6 2 1 2 4 4 4 0 Photosynthetic reaction centre protein PAS_8 PF13188.7 OWF50732.1 - 6.9e-08 32.3 4.8 5 7.2 0.2 8.2 1 1 3 5 5 5 4 PAS domain SAM_1 PF00536.30 OWF50733.1 - 1.6e-26 92.5 0.2 4e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF50733.1 - 4.1e-21 74.8 0.4 1.5e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PID PF00640.23 OWF50733.1 - 5.1e-17 62.2 0.2 1.1e-16 61.2 0.2 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 OWF50733.1 - 0.0063 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Ank_2 PF12796.7 OWF50734.1 - 2.1e-43 146.8 2.3 1.6e-16 60.6 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF50734.1 - 3.3e-29 100.6 7.3 2.6e-10 40.3 0.1 6.6 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF50734.1 - 3.9e-29 100.7 0.0 8.1e-08 32.7 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF50734.1 - 6e-29 99.2 3.5 8.4e-05 22.8 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 OWF50734.1 - 7.8e-28 93.5 2.1 0.00032 20.9 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat YhhN PF07947.14 OWF50735.1 - 1.7e-43 148.4 18.4 2.2e-43 148.0 18.4 1.1 1 0 0 1 1 1 1 YhhN family Pkinase PF00069.25 OWF50736.1 - 2.9e-63 213.7 0.3 2.1e-62 210.9 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF50736.1 - 6.3e-32 110.9 1.4 1.5e-22 80.1 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF50736.1 - 5e-06 25.7 0.4 6.6e-06 25.3 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 OWF50736.1 - 1.3e-05 25.8 1.1 2.5e-05 24.9 0.4 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 OWF50736.1 - 2.2e-05 23.9 0.2 0.012 15.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OWF50736.1 - 0.00015 21.2 1.5 0.0002 20.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF50736.1 - 0.00086 19.3 0.3 0.068 13.1 0.2 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OWF50736.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4850 PF16142.5 OWF50736.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) TAFII28 PF04719.14 OWF50737.1 - 6.6e-38 128.7 0.3 1e-37 128.1 0.3 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 OWF50737.1 - 3.4e-06 27.3 0.0 7.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ORC6 PF05460.13 OWF50737.1 - 0.045 13.0 12.2 0.064 12.5 12.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SOBP PF15279.6 OWF50737.1 - 0.5 10.9 8.9 0.54 10.8 8.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.9 OWF50737.1 - 0.65 8.8 11.1 0.79 8.5 11.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 OWF50737.1 - 1.2 7.5 8.1 1.2 7.5 8.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 OWF50737.1 - 2.2 6.9 6.6 2.6 6.6 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 OWF50737.1 - 6.2 5.0 13.6 6.9 4.8 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 OWF50737.1 - 8.2 4.9 11.5 11 4.4 11.5 1.2 1 0 0 1 1 1 0 Macoilin family CDC50 PF03381.15 OWF50738.1 - 3.3e-95 318.8 0.2 4.3e-95 318.4 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 OWF50738.1 - 0.038 14.0 1.3 9.2 6.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2157 PF09925.9 OWF50738.1 - 0.053 13.3 0.7 2.7 7.8 0.9 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3955 PF13127.6 OWF50738.1 - 0.44 10.4 7.3 1.8 8.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) Tetraspanin PF00335.20 OWF50739.1 - 4.6e-48 163.9 9.3 5.1e-48 163.8 9.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 OWF50739.1 - 0.017 15.4 13.0 0.043 14.1 9.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) YtpI PF14007.6 OWF50739.1 - 0.18 11.9 0.3 0.18 11.9 0.3 2.7 3 0 0 3 3 3 0 YtpI-like protein DUF981 PF06168.11 OWF50739.1 - 2.2 8.2 11.6 0.12 12.2 6.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF981) Ldl_recept_b PF00058.17 OWF50740.1 - 8.8e-156 506.2 47.7 1.9e-11 44.3 0.0 20.4 20 0 0 20 20 20 18 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 OWF50740.1 - 7.1e-43 144.6 56.7 4.2e-12 46.1 8.4 4.9 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site SGL PF08450.12 OWF50740.1 - 2.7e-21 76.3 18.4 0.0073 15.9 0.1 11.3 6 4 3 10 10 10 6 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_a PF00057.18 OWF50740.1 - 1.6e-20 73.1 32.3 1.5e-11 44.3 11.1 3.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF5050 PF16472.5 OWF50740.1 - 1.8e-20 73.4 0.0 0.00018 20.8 0.0 5.0 4 2 0 4 4 4 4 Domain of unknown function (DUF5050) Arylesterase PF01731.20 OWF50740.1 - 1.8e-07 31.3 0.0 6.7 7.0 0.0 7.6 8 0 0 8 8 8 2 Arylesterase cEGF PF12662.7 OWF50740.1 - 0.011 15.7 23.4 1.1 9.2 2.4 5.5 4 1 0 4 4 4 0 Complement Clr-like EGF-like CLTH PF10607.9 OWF50741.1 - 2e-35 121.8 4.0 2.6e-35 121.5 4.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OWF50741.1 - 2.5e-09 36.8 0.4 9.1e-09 35.0 0.1 2.0 2 0 0 2 2 2 1 LisH TINF2_N PF14973.6 OWF50741.1 - 0.00098 19.5 0.4 0.0027 18.1 0.1 1.8 1 1 1 2 2 2 1 TERF1-interacting nuclear factor 2 N-terminus MyTH4 PF00784.17 OWF50742.1 - 1.1e-32 112.8 1.5 4.2e-32 110.8 0.3 2.7 3 0 0 3 3 3 1 MyTH4 domain RhoGAP PF00620.27 OWF50742.1 - 2.5e-31 108.5 0.0 6.3e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 OWF50742.1 - 1.8e-06 27.9 12.1 0.00023 21.2 5.8 2.7 2 0 0 2 2 2 2 WW domain PHD PF00628.29 OWF50743.1 - 5.7e-09 35.7 6.9 1.2e-08 34.7 6.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OWF50743.1 - 5.3e-07 29.1 2.1 9.8e-07 28.2 2.1 1.4 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 OWF50743.1 - 0.0043 17.2 3.8 0.0079 16.4 3.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zinc_ribbon_15 PF17032.5 OWF50743.1 - 0.044 14.5 2.7 0.044 14.5 2.7 1.6 2 0 0 2 2 2 0 zinc-ribbon family C1_1 PF00130.22 OWF50743.1 - 0.045 13.7 0.8 0.045 13.7 0.8 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C5HC2 PF02928.16 OWF50743.1 - 1.3 9.5 6.8 2.7 8.4 2.0 2.5 2 0 0 2 2 2 0 C5HC2 zinc finger DUF2197 PF09963.9 OWF50743.1 - 1.3 9.3 7.7 3.2 8.1 7.7 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-CW PF07496.15 OWF50743.1 - 1.3 9.1 6.9 0.64 10.1 4.4 1.8 2 0 0 2 2 2 0 CW-type Zinc Finger AATF-Che1 PF13339.6 OWF50744.1 - 1.3e-29 103.7 7.0 1.3e-29 103.7 7.0 5.2 3 3 1 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 OWF50744.1 - 8.7e-29 99.9 1.3 8.7e-29 99.9 1.3 2.9 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal DUF3263 PF11662.8 OWF50744.1 - 0.022 14.6 1.3 0.21 11.5 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3263) Stealth_CR2 PF11380.8 OWF50745.1 - 2.7e-46 156.2 1.3 1.7e-45 153.6 0.1 2.6 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 OWF50745.1 - 9.2e-24 83.1 1.0 2.8e-23 81.5 1.0 1.9 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 OWF50745.1 - 3.8e-20 71.5 1.3 1.1e-19 70.0 1.3 1.9 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 OWF50745.1 - 3.5e-14 53.0 34.3 4.8e-09 36.5 14.1 2.5 2 0 0 2 2 2 2 LNR domain GlcNAc-1_reg PF18440.1 OWF50745.1 - 9.4e-14 51.4 0.1 2.7e-13 49.9 0.1 1.9 1 0 0 1 1 1 1 Putative GlcNAc-1 phosphotransferase regulatory domain Stealth_CR1 PF17101.5 OWF50745.1 - 4.6e-12 45.4 0.2 9.2e-12 44.5 0.2 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 RRM_9 PF18444.1 OWF50745.1 - 0.073 12.9 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif EF-hand_1 PF00036.32 OWF50745.1 - 0.13 11.8 0.1 0.78 9.4 0.0 2.5 2 0 0 2 2 2 0 EF hand Glyco_hydro_38C PF07748.13 OWF50746.1 - 1.4e-23 84.2 0.1 5.2e-23 82.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38N PF01074.22 OWF50746.1 - 8.7e-18 64.7 0.3 1.3e-17 64.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 OWF50746.1 - 3.2e-17 62.5 0.1 6.6e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38N PF01074.22 OWF50747.1 - 7.7e-25 87.8 0.1 1e-24 87.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Cas9_a PF18470.1 OWF50747.1 - 0.038 13.5 0.2 0.065 12.8 0.2 1.3 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain P53_tetramer PF07710.11 OWF50748.1 - 7.6e-07 28.4 1.9 1.1e+02 2.2 0.0 9.2 11 0 0 11 11 11 0 P53 tetramerisation motif DicB PF05358.11 OWF50748.1 - 1.6e-06 28.2 14.9 12 6.1 0.1 8.1 1 1 9 10 10 10 1 DicB protein Potassium_chann PF11404.8 OWF50748.1 - 9.1e-06 25.4 7.1 64 3.5 0.0 9.8 11 0 0 11 11 11 0 Potassium voltage-gated channel PTS_2-RNA PF01885.16 OWF50748.1 - 8.3e-05 22.7 0.1 1.4 8.9 0.0 4.5 1 1 1 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family GSHPx PF00255.19 OWF50748.1 - 0.00055 19.5 0.2 22 4.7 0.0 4.8 1 1 5 6 6 6 0 Glutathione peroxidase DNA_ligase_OB_2 PF14743.6 OWF50748.1 - 0.034 14.2 3.6 0.32 11.1 0.2 3.6 2 2 2 4 4 4 0 DNA ligase OB-like domain Lysyl_oxidase PF01186.17 OWF50748.1 - 0.069 12.8 1.5 26 4.4 0.0 3.9 1 1 4 6 6 6 0 Lysyl oxidase EF1G PF00647.19 OWF50748.1 - 0.11 12.6 1.7 51 4.0 0.0 4.4 1 1 4 5 5 5 0 Elongation factor 1 gamma, conserved domain DUF3539 PF12058.8 OWF50748.1 - 0.11 12.7 2.3 56 4.0 0.0 5.4 1 1 6 8 8 8 0 Protein of unknown function (DUF3539) QVR PF17064.5 OWF50748.1 - 1.2 9.4 10.2 18 5.6 0.7 3.7 1 1 3 4 4 4 0 Sleepless protein DicB PF05358.11 OWF50749.1 - 6.4e-16 58.2 69.5 74 3.6 0.1 26.6 1 1 46 47 47 47 46 DicB protein Arm PF00514.23 OWF50750.1 - 0.03 14.4 0.0 1.5 8.9 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 OWF50750.1 - 0.076 13.3 0.6 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 PqqA PF08042.11 OWF50750.1 - 0.56 10.3 3.2 7.5 6.7 0.1 2.4 2 0 0 2 2 2 0 PqqA family CH PF00307.31 OWF50751.1 - 1.4e-12 47.8 0.1 1.8e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Lipase_GDSL_2 PF13472.6 OWF50752.1 - 0.00045 20.6 0.0 0.001 19.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF50752.1 - 0.14 12.2 0.0 0.67 9.9 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Glyco_transf_11 PF01531.16 OWF50753.1 - 3.9e-32 111.7 3.3 5e-32 111.3 3.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 SPATA48 PF15073.6 OWF50754.1 - 3e-08 34.0 24.5 8.6 6.7 0.1 11.1 1 1 13 14 14 14 14 Spermatogenesis-associated protein 48 Myb_DNA-bind_7 PF15963.5 OWF50755.1 - 9.6e-26 89.5 6.1 9.6e-26 89.5 6.1 2.5 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OWF50755.1 - 1.3e-05 25.3 0.0 3.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain tRNA_edit PF04073.15 OWF50756.1 - 9e-17 61.3 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain MFS_1 PF07690.16 OWF50758.1 - 8.5e-25 87.4 26.1 8.5e-25 87.4 26.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OWF50758.1 - 2.1e-05 23.0 8.0 2.2e-05 23.0 5.1 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family VWA PF00092.28 OWF50759.1 - 2.5e-10 40.9 0.0 3.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF50760.1 - 9.7e-10 39.0 0.0 1.4e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF50760.1 - 6.9e-05 23.4 0.0 0.00011 22.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain SICA_alpha PF12887.7 OWF50760.1 - 0.15 11.9 0.0 0.49 10.2 0.0 1.7 2 0 0 2 2 2 0 SICA extracellular alpha domain VWA PF00092.28 OWF50761.1 - 5.5e-09 36.5 0.0 8.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Stathmin PF00836.19 OWF50761.1 - 0.087 12.8 0.8 0.34 10.9 0.6 2.0 3 0 0 3 3 3 0 Stathmin family RabGAP-TBC PF00566.18 OWF50762.1 - 5.2e-48 163.5 2.4 7.4e-48 163.0 0.0 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 OWF50762.1 - 3.8e-34 117.0 0.1 1.7e-19 69.8 0.0 2.6 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 OWF50762.1 - 0.00063 19.1 4.8 0.0009 18.6 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 OWF50762.1 - 0.00093 19.0 0.4 0.0067 16.3 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 OWF50762.1 - 0.01 15.6 0.2 0.047 13.5 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 OWF50762.1 - 0.015 14.8 0.2 0.07 12.7 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 OWF50762.1 - 0.088 13.3 0.6 0.54 10.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair WSC PF01822.19 OWF50763.1 - 1.5e-05 25.1 4.4 1.5e-05 25.1 4.4 2.2 2 0 0 2 2 2 1 WSC domain PAN_1 PF00024.26 OWF50763.1 - 0.00011 22.1 2.1 0.00032 20.6 0.3 2.5 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 OWF50763.1 - 0.062 13.1 0.9 0.062 13.1 0.9 2.3 2 0 0 2 2 2 0 PAN-like domain FAM221 PF14753.6 OWF50764.1 - 1.1e-88 296.0 7.0 1.4e-88 295.6 7.0 1.1 1 0 0 1 1 1 1 Protein FAM221A/B DUF3827 PF12877.7 OWF50765.1 - 2.2e-11 42.9 9.1 2.2e-11 42.9 9.1 4.5 3 1 2 5 5 5 2 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 OWF50765.1 - 0.26 12.2 1.4 0.47 11.4 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ShK PF01549.24 OWF50766.1 - 9.6e-12 45.2 41.6 3.5e-05 24.2 8.0 3.4 3 0 0 3 3 3 3 ShK domain-like DUF1590 PF07629.11 OWF50766.1 - 0.05 13.4 6.1 0.29 11.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) Patched PF02460.18 OWF50767.1 - 4.7e-131 438.5 20.3 9.1e-131 437.5 20.3 1.4 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF50767.1 - 8.5e-34 116.6 9.1 8.5e-34 116.6 9.1 2.8 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation KR PF08659.10 OWF50768.1 - 2.6e-54 183.9 0.0 4.9e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 OWF50768.1 - 3.6e-37 128.6 0.0 1.8e-36 126.3 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 OWF50768.1 - 1.9e-28 99.5 0.0 4.1e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.20 OWF50768.1 - 7.4e-21 74.3 1.2 1.6e-20 73.2 1.2 1.5 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 OWF50768.1 - 3.5e-09 36.9 0.1 1e-08 35.4 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OWF50768.1 - 1.2e-08 34.7 0.9 4.2e-08 32.9 0.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF50768.1 - 1.5e-05 24.7 0.0 4.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase BAH PF01426.18 OWF50768.1 - 0.1 12.5 0.2 33 4.4 0.1 3.4 3 0 0 3 3 3 0 BAH domain ketoacyl-synt PF00109.26 OWF50769.1 - 6.6e-82 274.9 0.0 1.2e-81 274.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OWF50769.1 - 3.5e-38 130.3 0.1 7.1e-38 129.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OWF50769.1 - 9.5e-16 58.3 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 OWF50769.1 - 1.3e-06 28.0 0.1 2.5e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Acyl_transf_1 PF00698.21 OWF50769.1 - 0.038 13.5 0.2 0.058 12.9 0.2 1.3 1 0 0 1 1 1 0 Acyl transferase domain ACP_syn_III PF08545.10 OWF50769.1 - 0.051 13.4 1.7 0.082 12.8 0.6 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Patched PF02460.18 OWF50770.1 - 1.1e-142 476.9 24.0 1.3e-142 476.6 24.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF50770.1 - 1.8e-38 131.8 4.1 1.8e-38 131.8 4.1 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OWF50770.1 - 0.085 11.8 24.3 0.079 11.9 6.1 2.3 2 0 0 2 2 2 0 MMPL family ACR_tran PF00873.19 OWF50770.1 - 1.6 6.3 13.7 2.5 5.7 13.7 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Ras PF00071.22 OWF50771.1 - 1.4e-36 125.6 0.2 1.8e-36 125.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50771.1 - 1.1e-17 64.3 0.0 2.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50771.1 - 2.1e-06 27.3 0.1 3.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF50771.1 - 7.5e-05 22.8 0.1 0.00031 20.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF50771.1 - 0.00059 19.4 0.1 0.0011 18.6 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OWF50771.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 OWF50771.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF50771.1 - 0.016 15.1 0.2 4.2 7.2 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OWF50771.1 - 0.036 13.8 0.1 0.27 11.0 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3545 PF12065.8 OWF50771.1 - 0.16 12.0 0.3 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) PA14 PF07691.12 OWF50773.1 - 2.7e-05 24.0 18.0 2.7 7.8 0.9 6.5 1 1 1 2 2 2 1 PA14 domain C1q PF00386.21 OWF50773.1 - 0.00015 22.0 17.5 0.58 10.4 1.2 4.2 1 1 3 4 4 4 4 C1q domain CLP1_N PF16573.5 OWF50773.1 - 0.024 14.9 1.5 1.7e+02 2.5 0.0 5.1 1 1 6 8 8 8 0 N-terminal beta-sandwich domain of polyadenylation factor MAP PF03642.13 OWF50774.1 - 1.2e-11 44.8 8.2 4 7.8 0.0 9.7 1 1 10 12 12 12 4 MAP domain C1q PF00386.21 OWF50774.1 - 0.0023 18.1 30.0 2 8.6 1.0 6.2 1 1 8 9 9 9 8 C1q domain CLP1_N PF16573.5 OWF50774.1 - 0.022 14.9 1.2 1.2e+02 3.0 0.0 5.9 3 2 5 9 9 9 0 N-terminal beta-sandwich domain of polyadenylation factor PA14 PF07691.12 OWF50774.1 - 0.028 14.2 29.0 1.8e+04 -19.9 29.0 9.6 1 1 0 1 1 1 0 PA14 domain Pilin_PilA PF14245.6 OWF50774.1 - 0.03 14.3 0.5 49 3.9 0.0 4.6 3 2 2 5 5 5 0 Type IV pilin PilA Laminin_G_3 PF13385.6 OWF50774.1 - 0.085 13.0 3.2 27 4.9 0.1 4.8 4 2 2 6 6 6 0 Concanavalin A-like lectin/glucanases superfamily DUF1481 PF07356.12 OWF50774.1 - 1.8 8.3 19.8 1.1 9.0 1.1 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF1481) Neurexophilin PF06312.12 OWF50775.1 - 1.7e-05 24.4 0.1 4.9e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Neurexophilin PC-Esterase PF13839.6 OWF50775.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Invasin_D3 PF09134.10 OWF50775.1 - 0.036 14.4 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Invasin, domain 3 Filamin PF00630.19 OWF50775.1 - 0.051 14.4 0.0 0.12 13.3 0.0 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat Laminin_G_3 PF13385.6 OWF50776.1 - 0.00022 21.4 0.5 0.00045 20.4 0.5 1.5 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OWF50776.1 - 0.039 14.5 0.1 1 9.9 0.1 2.2 1 1 0 1 1 1 0 Laminin G domain SDF PF00375.18 OWF50777.1 - 6.1e-97 325.1 30.4 7.6e-97 324.8 30.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Ank_2 PF12796.7 OWF50780.1 - 8.1e-51 170.5 25.8 2.1e-14 53.9 0.6 5.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50780.1 - 1.6e-32 111.4 11.8 7.3e-07 29.6 0.0 7.8 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF50780.1 - 3e-29 100.7 10.7 1.3e-06 28.5 0.2 7.8 3 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50780.1 - 1.2e-27 92.9 11.9 0.01 16.3 0.0 10.3 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 OWF50780.1 - 6.4e-25 86.5 15.3 0.00091 19.6 0.1 9.4 9 1 1 10 10 10 7 Ankyrin repeat SOCS_box PF07525.16 OWF50780.1 - 2.6e-10 40.5 1.6 7e-10 39.1 1.6 1.7 1 0 0 1 1 1 1 SOCS box CRR7 PF12095.8 OWF50780.1 - 0.054 13.9 1.4 7 7.2 0.1 3.6 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 Lipase_GDSL_2 PF13472.6 OWF50781.1 - 0.00084 19.8 0.0 0.0009 19.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RPN6_N PF18055.1 OWF50782.1 - 5.1e-35 120.4 0.7 5.1e-35 120.4 0.7 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OWF50782.1 - 3.8e-17 62.7 1.0 9.2e-17 61.5 0.1 2.2 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 OWF50782.1 - 4.6e-15 55.0 0.6 1.2e-14 53.7 0.6 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 OWF50782.1 - 0.045 14.1 6.7 0.32 11.3 2.6 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PIN_3 PF13470.6 OWF50782.1 - 0.068 13.9 0.3 0.24 12.2 0.1 1.9 2 0 0 2 2 2 0 PIN domain NUDIX PF00293.28 OWF50783.1 - 7.4e-18 64.8 0.0 9.7e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Hist_deacetyl PF00850.19 OWF50784.1 - 1e-80 271.5 0.0 1e-80 271.5 0.0 3.2 3 0 0 3 3 3 2 Histone deacetylase domain HDAC4_Gln PF12203.8 OWF50784.1 - 1.3e-11 44.5 46.8 1.3e-11 44.5 46.8 4.7 5 1 1 6 6 6 1 Glutamine rich N terminal domain of histone deacetylase 4 Ntox5 PF15543.6 OWF50785.1 - 0.00047 20.0 0.0 5.6 6.8 0.0 4.4 1 1 1 4 4 4 2 Bacterial toxin 5 DoxX_3 PF13781.6 OWF50785.1 - 1 10.0 3.2 41 4.9 0.0 4.2 3 1 3 6 6 6 0 DoxX-like family ECH_1 PF00378.20 OWF50786.1 - 1.7e-19 70.1 0.0 2e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF50786.1 - 1.7e-09 37.6 0.0 2.1e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SepQ PF06622.11 OWF50786.1 - 0.019 14.1 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 SepQ protein Gal-3-0_sulfotr PF06990.11 OWF50787.1 - 3.1e-41 141.6 0.9 3.9e-41 141.3 0.9 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF50787.1 - 0.0011 19.0 0.9 0.0026 17.7 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family Archease PF01951.16 OWF50787.1 - 0.011 16.0 0.1 3.6 7.8 0.0 2.6 3 0 0 3 3 3 0 Archease protein family (MTH1598/TM1083) Gal-3-0_sulfotr PF06990.11 OWF50788.1 - 4.5e-38 131.2 0.6 6.1e-38 130.7 0.6 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF50788.1 - 0.00023 21.2 1.8 0.00058 19.8 0.1 2.3 2 1 0 2 2 2 1 Sulfotransferase family Acyltransferase PF01553.21 OWF50789.1 - 9.8e-23 80.3 0.0 1.8e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MAP65_ASE1 PF03999.12 OWF50790.1 - 4.4e-113 379.1 30.7 4.4e-113 379.1 30.7 1.3 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) PNRC PF15365.6 OWF50791.1 - 6.8e-07 28.9 5.0 6.8e-07 28.9 5.0 2.7 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif zf-RING_2 PF13639.6 OWF50792.1 - 3.5e-13 49.7 11.1 1.2e-12 47.9 11.1 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OWF50792.1 - 1e-08 35.3 8.2 1e-08 35.3 8.2 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OWF50792.1 - 2.1e-08 33.8 5.9 2.1e-08 33.8 5.9 2.6 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF50792.1 - 4.2e-07 29.7 10.5 4.2e-07 29.7 10.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF50792.1 - 5.9e-07 29.2 10.2 1.4e-06 28.0 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF50792.1 - 3.2e-06 27.0 8.7 7.5e-06 25.8 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF50792.1 - 3.9e-05 23.4 7.5 3.9e-05 23.4 7.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF50792.1 - 0.00015 21.7 6.7 0.00047 20.1 6.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OWF50792.1 - 0.00068 19.6 3.5 0.00068 19.6 3.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OWF50792.1 - 0.0044 16.8 7.1 0.0044 16.8 7.1 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 OWF50792.1 - 0.35 11.0 9.9 0.74 10.0 9.9 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 OWF50792.1 - 0.41 10.9 7.7 1.4 9.2 7.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OWF50792.1 - 3.3 7.4 15.0 0.096 12.3 7.8 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OWF50792.1 - 3.6 7.4 7.5 13 5.7 7.5 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain M-inducer_phosp PF06617.13 OWF50794.1 - 4.9e-18 65.4 20.5 3.9e-17 62.5 20.5 2.1 1 1 0 1 1 1 1 M-phase inducer phosphatase Rhodanese PF00581.20 OWF50794.1 - 5.3e-10 39.8 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain SLBP_RNA_bind PF15247.6 OWF50795.1 - 4.3e-25 87.6 5.6 4.3e-25 87.6 5.6 2.2 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain ARID PF01388.21 OWF50796.1 - 1.4e-16 60.9 0.0 3.6e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain COE1_DBD PF16422.5 OWF50797.1 - 2.1e-130 433.1 0.1 2.9e-130 432.7 0.1 1.1 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 OWF50797.1 - 7.2e-30 102.4 0.8 1.2e-29 101.7 0.8 1.4 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 OWF50797.1 - 4.8e-13 49.0 0.2 2.5e-12 46.7 0.3 2.1 2 0 0 2 2 2 1 IPT/TIG domain Cpn60_TCP1 PF00118.24 OWF50798.1 - 2.6e-158 527.7 5.0 2.9e-158 527.5 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Galactosyl_T PF01762.21 OWF50799.1 - 1.2e-31 110.1 0.1 1.7e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase SANT_DAMP1_like PF16282.5 OWF50799.1 - 0.039 14.2 0.2 0.73 10.1 0.2 2.5 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Galactosyl_T PF01762.21 OWF50800.1 - 7.5e-47 159.7 0.2 1.6e-46 158.6 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase SdpI PF13630.6 OWF50800.1 - 0.15 12.2 0.9 0.3 11.2 0.9 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family PBP-Tp47_c PF14888.6 OWF50800.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain C Galactosyl_T PF01762.21 OWF50801.1 - 1.2e-31 110.1 0.1 1.7e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase SANT_DAMP1_like PF16282.5 OWF50801.1 - 0.038 14.2 0.1 0.73 10.1 0.2 2.5 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 ECSCR PF15820.5 OWF50802.1 - 0.0089 15.8 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 OWF50802.1 - 0.032 15.1 0.9 0.11 13.4 1.0 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF50802.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_S49_N PF08496.10 OWF50802.1 - 0.19 11.8 4.2 11 6.1 2.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Helicase_C PF00271.31 OWF50803.1 - 1.2e-12 48.1 0.1 1.7e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TatD_DNase PF01026.21 OWF50804.1 - 3.8e-16 59.2 0.0 4e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase V-set PF07686.17 OWF50805.1 - 2e-13 50.4 3.6 1.9e-06 28.0 0.9 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 OWF50805.1 - 8e-13 48.8 1.7 1e-05 26.1 0.6 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF50805.1 - 9.4e-12 44.9 0.1 2.1e-05 24.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 OWF50805.1 - 5.9e-09 36.0 2.6 9.5e-05 22.5 0.5 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF50805.1 - 8.2e-09 35.7 5.1 0.0014 18.9 0.1 3.4 1 1 1 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 OWF50805.1 - 1.4e-07 31.8 2.2 0.00073 19.9 0.6 3.6 2 2 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 OWF50805.1 - 2.9e-05 24.2 1.2 7.2 7.0 0.1 4.0 3 1 1 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 OWF50805.1 - 0.00026 21.0 0.1 0.68 10.0 0.0 2.4 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Tudor_2 PF18104.1 OWF50805.1 - 0.025 14.3 5.7 2 8.2 0.0 4.3 5 0 0 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain DUF281 PF03436.13 OWF50805.1 - 0.14 12.6 0.1 38 4.8 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF281) DUF756 PF05506.12 OWF50805.1 - 0.16 12.9 0.5 2.6 9.0 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF756) SSF PF00474.17 OWF50807.1 - 1.3e-137 459.0 19.6 1.9e-137 458.4 19.6 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family HPP PF04982.13 OWF50807.1 - 1 9.6 7.3 0.077 13.2 0.6 2.7 3 0 0 3 3 3 0 HPP family Ras PF00071.22 OWF50809.1 - 1.7e-35 122.0 0.3 2e-35 121.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50809.1 - 5.1e-16 59.0 0.0 8.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF50810.1 - 1.3e-36 125.7 0.3 1.5e-36 125.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50810.1 - 6.4e-17 61.9 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50810.1 - 0.023 14.2 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family RVT_1 PF00078.27 OWF50811.1 - 1.2e-33 116.5 0.1 1.9e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OWF50811.1 - 0.17 12.6 1.9 0.6 10.9 1.9 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Peptidase_M41 PF01434.18 OWF50812.1 - 1.1e-05 25.4 0.0 0.077 12.8 0.0 3.3 1 1 0 3 3 3 2 Peptidase family M41 APC_u13 PF16634.5 OWF50812.1 - 0.00091 19.1 5.3 34 4.4 0.0 6.4 5 2 0 6 6 6 1 Unstructured region on APC between APC_crr and SAMP DUF1610 PF07754.11 OWF50812.1 - 0.012 15.5 0.7 1.4e+02 2.6 0.0 5.5 6 1 1 7 7 7 0 Domain of unknown function (DUF1610) Ras PF00071.22 OWF50813.1 - 8.1e-34 116.6 0.0 9.7e-34 116.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50813.1 - 2.1e-11 44.1 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OWF50813.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein PHD_Oberon PF07227.11 OWF50813.1 - 0.012 15.5 1.4 0.021 14.7 0.7 1.7 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein Baculo_ODV-E27 PF05314.11 OWF50813.1 - 0.034 13.3 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 AAA_22 PF13401.6 OWF50813.1 - 0.038 14.3 0.0 0.22 11.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OWF50813.1 - 0.09 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 OWF50814.1 - 1.1e-32 112.9 0.7 1.3e-32 112.7 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50814.1 - 2.3e-13 50.4 0.2 3.9e-13 49.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF50815.1 - 1.6e-36 125.4 0.1 1.9e-36 125.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50815.1 - 1.2e-13 51.3 0.0 2.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_38N PF01074.22 OWF50816.1 - 2.4e-90 302.8 7.6 2.4e-90 302.8 7.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OWF50816.1 - 1e-34 120.5 0.0 2.1e-34 119.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OWF50816.1 - 2.2e-21 75.8 0.7 5.8e-21 74.5 0.7 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Pkinase PF00069.25 OWF50817.1 - 1.6e-50 171.9 0.0 4.4e-50 170.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF50817.1 - 7.1e-26 91.0 0.0 5.5e-16 58.6 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase RICTOR_V PF14668.6 OWF50817.1 - 1.1e-05 25.6 1.1 3.9 7.8 0.0 3.8 3 0 0 3 3 3 3 Rapamycin-insensitive companion of mTOR, domain 5 Mo25 PF08569.11 OWF50817.1 - 0.001 18.5 0.0 0.017 14.5 0.0 2.7 2 1 0 2 2 2 1 Mo25-like DUF5584 PF17822.1 OWF50817.1 - 0.083 12.4 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5584) TetR_C_29 PF17938.1 OWF50817.1 - 0.092 12.8 0.7 0.34 11.0 0.3 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HEAT PF02985.22 OWF50817.1 - 0.12 12.6 2.9 57 4.4 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat CelTOS PF18659.1 OWF50817.1 - 2.3 8.7 4.9 6.4 7.2 0.0 4.2 6 0 0 6 6 6 0 Cell-traversal protein for ookinetes and sporozoites IBN_N PF03810.19 OWF50817.1 - 7.3 6.6 8.7 8.6 6.4 0.0 3.9 4 0 0 4 4 4 0 Importin-beta N-terminal domain Cnd1 PF12717.7 OWF50817.1 - 9.2 6.3 14.5 0.2 11.7 0.3 4.4 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Aldose_epim PF01263.20 OWF50818.1 - 5.3e-95 318.2 0.9 6e-95 318.0 0.9 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RAMP PF04901.13 OWF50818.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Receptor activity modifying family DUF5067 PF16729.5 OWF50818.1 - 0.27 11.1 2.1 1.6 8.7 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5067) CCDC32 PF14989.6 OWF50819.1 - 8.2e-09 35.6 2.7 8.2e-09 35.6 2.7 1.6 1 1 1 2 2 2 1 Coiled-coil domain containing 32 SF3b10 PF07189.11 OWF50820.1 - 0.18 12.0 37.3 8.6 6.6 1.0 8.1 1 1 8 9 9 9 0 Splicing factor 3B subunit 10 (SF3b10) DUF5512 PF17631.2 OWF50820.1 - 1.2 9.2 4.6 17 5.4 0.1 4.0 1 1 6 7 7 7 0 Family of unknown function (DUF5512) Ras PF00071.22 OWF50821.1 - 1.6e-50 170.8 0.0 2e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF50821.1 - 7.4e-21 74.6 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF50821.1 - 0.00092 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF50821.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 OWF50821.1 - 0.2 11.0 0.0 0.42 10.0 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Helicase_C PF00271.31 OWF50822.1 - 5.8e-21 74.9 0.4 2.2e-20 73.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF50822.1 - 3.5e-19 69.4 2.7 1.2e-18 67.7 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF50822.1 - 5.8e-17 62.0 0.0 1.7e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase FANCM-MHF_bd PF16783.5 OWF50822.1 - 9.1e-14 51.5 0.0 9e-13 48.3 0.0 2.8 2 0 0 2 2 2 1 FANCM to MHF binding domain DUF4497 PF14924.6 OWF50823.1 - 1.7e-22 79.9 0.0 5.7e-22 78.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4497) HPHLAWLY PF14925.6 OWF50823.1 - 1.3e-05 24.1 34.7 1.3e-05 24.1 34.7 3.1 2 1 1 3 3 3 2 Domain of unknown function PLDc_2 PF13091.6 OWF50824.1 - 2.7e-29 101.7 0.1 3.6e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 OWF50824.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif FAM83 PF07894.12 OWF50824.1 - 0.01 15.4 1.7 0.32 10.5 1.7 2.1 1 1 0 1 1 1 0 FAM83 A-H SPA PF08616.10 OWF50824.1 - 0.047 13.6 0.6 0.66 10.0 0.1 2.1 1 1 0 2 2 2 0 Stabilization of polarity axis OST-HTH PF12872.7 OWF50825.1 - 9.1e-45 150.4 0.1 5.3e-13 48.6 0.0 7.9 8 0 0 8 8 8 6 OST-HTH/LOTUS domain NYN PF01936.18 OWF50825.1 - 3.7e-17 63.2 0.1 8.8e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 NYN domain Limkain-b1 PF11608.8 OWF50825.1 - 1.8e-16 60.0 0.0 5.2e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Limkain b1 RRM_1 PF00076.22 OWF50825.1 - 9.6e-06 25.3 0.0 0.15 11.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SSTK-IP PF15836.5 OWF50825.1 - 0.8 9.9 4.9 0.44 10.7 2.0 2.1 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Glycos_transf_2 PF00535.26 OWF50826.1 - 1.6e-21 76.8 0.0 2.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OWF50826.1 - 2.2e-09 37.6 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OWF50826.1 - 3.1e-08 34.0 0.3 1.2e-05 25.7 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 OWF50826.1 - 2.2e-07 30.7 0.1 1.1e-06 28.4 0.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase like family 2 GramPos_pilinD1 PF16555.5 OWF50826.1 - 0.035 14.3 0.0 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain DHHC PF01529.20 OWF50827.1 - 2.8e-31 108.4 11.7 2.8e-31 108.4 11.7 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase SH3_2 PF07653.17 OWF50827.1 - 0.057 13.1 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain ANAPC16 PF17256.2 OWF50828.1 - 0.053 13.9 0.2 0.14 12.5 0.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 16 Trypsin PF00089.26 OWF50829.1 - 1.4e-65 221.3 0.1 3.1e-65 220.1 0.1 1.7 1 0 0 1 1 1 1 Trypsin Fz PF01392.22 OWF50829.1 - 1.6e-35 122.1 12.8 6.4e-20 71.8 4.4 4.2 5 0 0 5 5 5 2 Fz domain SRCR_2 PF15494.6 OWF50829.1 - 1.7e-13 50.9 0.4 6.3e-13 49.1 0.4 2.1 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 OWF50829.1 - 3e-10 40.5 0.4 3e-10 40.5 0.4 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 OWF50829.1 - 5.2e-09 36.2 36.7 8.4e-08 32.3 10.6 3.4 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SEA PF01390.20 OWF50829.1 - 1.9e-06 27.9 0.6 3.3e-06 27.2 0.6 1.3 1 0 0 1 1 1 1 SEA domain Trypsin_2 PF13365.6 OWF50829.1 - 4.2e-05 24.5 0.0 0.00011 23.1 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Hepsin-SRCR PF09272.10 OWF50829.1 - 0.00011 22.7 0.1 0.00026 21.5 0.1 1.6 1 0 0 1 1 1 1 Hepsin, SRCR domain DUF1986 PF09342.11 OWF50829.1 - 0.00012 22.4 0.0 0.00033 21.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Peptidase_S78_2 PF14550.6 OWF50830.1 - 0.017 15.2 0.7 8.2 6.5 0.1 2.9 1 1 1 3 3 3 0 Putative phage serine protease XkdF CP_ATPgrasp_2 PF14403.6 OWF50830.1 - 0.074 12.0 0.1 0.54 9.1 0.1 1.9 1 1 1 2 2 2 0 Circularly permuted ATP-grasp type 2 DUF3046 PF11248.8 OWF50830.1 - 0.16 12.4 0.0 31 5.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3046) PAN_4 PF14295.6 OWF50831.1 - 0.0031 17.4 1.0 0.0031 17.4 1.0 2.3 2 1 0 2 2 2 1 PAN domain EB PF01683.18 OWF50831.1 - 0.0045 17.3 12.4 0.077 13.3 12.4 2.3 1 1 0 1 1 1 1 EB module TIL PF01826.17 OWF50831.1 - 0.044 14.0 11.1 0.2 11.9 3.4 2.4 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain PAN_3 PF08277.12 OWF50831.1 - 0.048 13.5 0.4 0.048 13.5 0.4 2.4 2 1 0 2 2 2 0 PAN-like domain TRAPPC-Trs85 PF12739.7 OWF50832.1 - 1.2e-133 446.1 7.1 1.8e-133 445.5 7.1 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 OWF50832.1 - 0.74 10.1 2.7 30 5.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ERCC3_RAD25_C PF16203.5 OWF50833.1 - 8.7e-05 21.8 11.5 0.19 10.9 0.3 5.3 1 1 4 5 5 5 2 ERCC3/RAD25/XPB C-terminal helicase Pertactin PF03212.14 OWF50833.1 - 0.0015 18.4 9.2 0.18 11.7 0.4 3.8 1 1 2 4 4 4 3 Pertactin SspK PF08176.12 OWF50833.1 - 0.0043 17.3 20.4 4.1 7.8 0.1 10.4 5 4 4 10 10 10 1 Small acid-soluble spore protein K family Calx-beta PF03160.14 OWF50833.1 - 0.0068 16.6 5.9 1.1 9.5 0.8 4.8 1 1 5 6 6 6 1 Calx-beta domain DUF3395 PF11875.8 OWF50833.1 - 0.13 12.2 0.3 61 3.5 0.1 3.9 1 1 1 3 3 3 0 Domain of unknown function (DUF3395) DcuC PF03606.15 OWF50833.1 - 0.24 9.8 3.6 3.6 5.9 0.2 2.8 2 1 1 3 3 3 0 C4-dicarboxylate anaerobic carrier DUF2039 PF10217.9 OWF50833.1 - 1.3 9.4 15.7 15 6.0 0.3 4.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) DUF5049 PF16468.5 OWF50834.1 - 2.9e-06 27.1 11.4 17 5.4 0.0 8.3 3 3 4 7 7 7 5 Domain of unknown function (DUF5049) Methyltransf_28 PF02636.17 OWF50834.1 - 0.0089 15.7 4.6 2.8 7.5 0.2 3.3 1 1 2 3 3 3 3 Putative S-adenosyl-L-methionine-dependent methyltransferase LolA_like PF17131.4 OWF50834.1 - 0.012 15.3 0.6 44 3.7 0.0 4.0 1 1 0 3 3 3 0 Outer membrane lipoprotein-sorting protein Alpha_kinase PF02816.18 OWF50835.1 - 8.2e-23 81.5 3.8 8.4e-23 81.4 3.0 1.4 1 1 1 2 2 2 1 Alpha-kinase family Methyltransf_7 PF03492.15 OWF50835.1 - 0.042 13.1 0.4 0.66 9.1 0.1 2.1 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase DUF3408 PF11888.8 OWF50836.1 - 4.9e-05 23.5 0.1 2.7 8.2 0.0 6.7 3 2 2 7 7 7 1 Protein of unknown function (DUF3408) PRTase_3 PF15610.6 OWF50836.1 - 0.15 11.3 0.1 20 4.3 0.0 3.2 2 2 2 4 4 4 0 PRTase ComF-like LtuB PF17455.2 OWF50836.1 - 2.4 8.8 7.5 18 6.0 0.2 5.1 2 2 5 7 7 7 0 Late transcription unit B MIP PF00230.20 OWF50838.1 - 1.3e-59 201.7 5.2 1.7e-59 201.3 5.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein SNF PF00209.18 OWF50839.1 - 1.8e-204 680.3 33.2 2.2e-204 680.0 33.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TrbC PF04956.13 OWF50839.1 - 0.09 13.0 1.4 0.41 10.9 0.3 2.5 1 1 1 2 2 2 0 TrbC/VIRB2 family PigN PF04987.14 OWF50840.1 - 1.1e-125 420.1 41.9 1.5e-125 419.6 41.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 OWF50840.1 - 1.3e-10 41.4 0.1 3.6e-07 30.1 0.1 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OWF50840.1 - 0.0025 17.2 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Cytochrom_B558a PF05038.13 OWF50841.1 - 4e-48 163.5 0.1 5.2e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.9 OWF50841.1 - 0.00027 21.2 8.9 0.0041 17.4 8.9 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 OWF50841.1 - 0.22 11.2 6.0 1.8 8.2 6.0 2.2 1 1 0 1 1 1 0 Transmembrane protein family 72 HHV-5_US34A PF17087.5 OWF50841.1 - 1.8 8.8 4.3 0.61 10.3 0.4 2.1 2 0 0 2 2 2 0 Herpesvirus US34A protein family AMP-binding PF00501.28 OWF50842.1 - 3.2e-83 279.7 0.2 4.2e-83 279.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF50842.1 - 2.1e-10 41.4 0.0 4.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain I-set PF07679.16 OWF50843.1 - 7.1e-31 106.1 0.3 6.2e-10 39.0 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF50843.1 - 3.7e-29 101.2 16.3 1.1e-12 48.4 0.2 6.1 7 0 0 7 7 5 3 Immunoglobulin domain Ig_2 PF13895.6 OWF50843.1 - 4.7e-20 71.7 6.0 4.7e-08 33.2 0.1 4.9 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 OWF50843.1 - 1.7e-13 50.5 20.8 1.2e-06 28.6 0.1 5.8 6 0 0 6 6 5 3 Immunoglobulin domain V-set PF07686.17 OWF50843.1 - 3e-09 37.0 9.5 0.071 13.3 0.1 7.5 5 3 2 7 7 7 3 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF50843.1 - 1.9e-05 24.8 0.2 0.15 12.3 0.0 3.8 4 0 0 4 4 3 2 T-cell surface glycoprotein CD3 delta chain RIFIN PF02009.16 OWF50843.1 - 0.00023 21.2 1.8 0.00036 20.5 1.8 1.2 1 0 0 1 1 1 1 Rifin C2-set_2 PF08205.12 OWF50843.1 - 0.0036 17.4 13.5 0.038 14.1 0.0 4.5 4 1 0 4 4 3 2 CD80-like C2-set immunoglobulin domain DAG1 PF05454.11 OWF50843.1 - 0.0086 15.5 2.0 0.018 14.5 2.0 1.5 1 1 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Podoplanin PF05808.11 OWF50843.1 - 0.025 14.7 13.1 0.065 13.3 13.1 1.7 1 0 0 1 1 1 0 Podoplanin MID_MedPIWI PF18296.1 OWF50843.1 - 0.044 13.6 1.8 0.076 12.8 1.8 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Prominin PF05478.11 OWF50843.1 - 0.05 11.6 0.5 0.069 11.1 0.5 1.1 1 0 0 1 1 1 0 Prominin Oxidored_q2 PF00420.24 OWF50843.1 - 0.17 11.6 1.5 0.96 9.1 1.5 2.1 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4366 PF14283.6 OWF50843.1 - 0.17 11.9 4.1 0.17 11.9 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Pex14_N PF04695.13 OWF50843.1 - 0.2 12.3 7.2 0.44 11.2 7.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Stevor PF17410.2 OWF50843.1 - 0.25 10.8 5.2 0.3 10.6 3.9 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Mucin PF01456.17 OWF50843.1 - 0.28 11.2 37.4 0.98 9.4 37.4 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M56 PF05569.11 OWF50843.1 - 0.31 10.2 1.2 0.51 9.5 1.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1180 PF06679.12 OWF50843.1 - 0.32 11.4 6.9 0.62 10.5 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AJAP1_PANP_C PF15298.6 OWF50843.1 - 1.2 9.3 20.7 3 8.0 20.7 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MGC-24 PF05283.11 OWF50843.1 - 1.7 9.1 18.0 5.5 7.4 18.0 1.9 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 OWF50843.1 - 2.9 7.8 18.1 17 5.3 18.1 2.0 1 1 0 1 1 1 0 TMEM154 protein family p450 PF00067.22 OWF50844.1 - 1.4e-62 212.0 0.1 1.7e-62 211.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF50845.1 - 1.3e-78 264.9 0.1 2e-78 264.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF50846.1 - 6.3e-80 269.2 0.0 7.3e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 G-gamma PF00631.22 OWF50846.1 - 0.084 12.9 1.4 1.5 8.9 0.1 3.0 2 1 1 3 3 3 0 GGL domain p450 PF00067.22 OWF50847.1 - 8.6e-22 77.5 0.0 1.1e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF50849.1 - 2.1e-18 66.3 0.0 2.6e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1229 PF06797.11 OWF50853.1 - 1.1 9.5 4.1 9.5 6.4 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1229) MgsA_C PF12002.8 OWF50854.1 - 7.6e-59 198.4 0.1 1.5e-58 197.4 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 OWF50854.1 - 6.4e-24 84.1 0.4 1.7e-23 82.8 0.4 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 OWF50854.1 - 7.6e-18 65.2 0.1 1.6e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OWF50854.1 - 3.8e-16 59.2 0.0 6.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF50854.1 - 3.1e-10 40.2 0.1 1.5e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OWF50854.1 - 9.5e-07 28.9 0.1 3.2e-06 27.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 OWF50854.1 - 1.3e-06 28.2 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 OWF50854.1 - 2.7e-06 26.9 0.1 0.066 12.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OWF50854.1 - 3.1e-06 27.7 0.2 0.00075 19.9 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OWF50854.1 - 5.5e-06 26.2 0.0 9.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 OWF50854.1 - 1.1e-05 24.8 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TRAF6_Z2 PF18048.1 OWF50854.1 - 6.8e-05 22.9 3.6 7.4e-05 22.8 1.6 2.1 2 0 0 2 2 1 1 TNF receptor-associated factor 6 zinc finger 2 AAA_30 PF13604.6 OWF50854.1 - 9.2e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OWF50854.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain ABC_tran PF00005.27 OWF50854.1 - 0.00015 22.3 0.2 0.00081 19.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_2 PF07724.14 OWF50854.1 - 0.00018 21.7 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 OWF50854.1 - 0.00018 21.1 0.0 0.0059 16.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 OWF50854.1 - 0.00047 20.4 3.4 0.007 16.6 0.9 3.4 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.6 OWF50854.1 - 0.00068 20.0 1.2 0.21 11.9 0.3 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 OWF50854.1 - 0.0012 19.3 0.0 0.0031 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OWF50854.1 - 0.0014 17.8 0.1 0.033 13.4 0.0 2.2 1 1 1 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 OWF50854.1 - 0.0016 18.4 0.2 0.052 13.5 0.1 2.1 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 OWF50854.1 - 0.0029 17.7 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 OWF50854.1 - 0.0043 16.8 1.3 0.0061 16.3 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 OWF50854.1 - 0.0048 16.9 0.2 0.014 15.3 0.2 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 OWF50854.1 - 0.0048 16.8 0.2 0.013 15.4 0.2 1.8 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 OWF50854.1 - 0.0085 16.5 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase zf-C2HC_2 PF13913.6 OWF50854.1 - 0.011 15.6 0.7 0.03 14.2 0.7 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type AAA_33 PF13671.6 OWF50854.1 - 0.017 15.3 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OWF50854.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UBZ_FAAP20 PF15750.5 OWF50854.1 - 0.025 14.5 0.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger AAA_24 PF13479.6 OWF50854.1 - 0.032 13.9 0.0 0.093 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OWF50854.1 - 0.033 14.2 2.1 5.3 7.0 0.0 2.7 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 OWF50854.1 - 0.038 13.4 0.0 0.3 10.5 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 OWF50854.1 - 0.042 13.8 0.2 0.091 12.7 0.2 1.6 1 1 0 1 1 1 0 NTPase zf-WRNIP1_ubi PF18279.1 OWF50854.1 - 0.054 14.2 0.4 0.32 11.7 0.4 2.5 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zeta_toxin PF06414.12 OWF50854.1 - 0.08 12.2 0.1 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 OWF50854.1 - 0.096 12.9 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OWF50854.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.6 OWF50854.1 - 0.17 12.3 0.5 0.52 10.7 0.5 2.0 1 1 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 OWF50854.1 - 0.39 11.7 1.9 1.6 9.8 0.4 2.9 2 0 0 2 2 1 0 C2H2-type zinc finger DNA_pol3_delta2 PF13177.6 OWF50854.1 - 0.44 10.3 5.4 0.24 11.2 2.2 2.4 2 1 0 2 2 1 0 DNA polymerase III, delta subunit ThiF PF00899.21 OWF50855.1 - 1.2e-16 60.8 0.0 1.8e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family Transglut_N PF00868.20 OWF50856.1 - 7.1e-35 119.9 0.0 6.9e-33 113.5 0.0 3.0 3 0 0 3 3 3 1 Transglutaminase family Transglut_C PF00927.22 OWF50856.1 - 4.3e-23 81.5 1.8 6.3e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 OWF50856.1 - 2.4e-15 56.9 0.2 5.6e-15 55.8 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.20 OWF50857.1 - 1.2e-34 119.2 0.0 3.6e-34 117.6 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 OWF50857.1 - 7.5e-13 48.5 1.1 3.5e-06 27.1 0.6 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 OWF50857.1 - 2.2e-08 34.5 0.0 5.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily HydF_tetramer PF18133.1 OWF50857.1 - 0.023 14.5 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain Ldl_recept_a PF00057.18 OWF50858.1 - 2.3e-12 46.9 23.4 1.3e-07 31.7 7.0 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A CUB PF00431.20 OWF50858.1 - 1.5e-08 34.9 0.1 0.00045 20.5 0.0 3.4 3 0 0 3 3 3 2 CUB domain Sld5 PF05916.11 OWF50859.1 - 8.7e-11 42.3 0.1 1.2e-10 41.8 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein LSM14 PF12701.7 OWF50861.1 - 3.8e-31 107.0 0.0 6.4e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OWF50861.1 - 1.3e-19 71.0 8.7 1.3e-19 71.0 8.7 2.6 3 0 0 3 3 3 2 FDF domain SM-ATX PF14438.6 OWF50861.1 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TAF4 PF05236.14 OWF50862.1 - 1.3e-62 212.1 11.9 2.6e-62 211.1 11.9 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 OWF50862.1 - 1.5e-36 124.4 0.6 7.5e-36 122.1 0.6 2.4 1 0 0 1 1 1 1 NHR1 homology to TAF TH1 PF04858.13 OWF50863.1 - 4.6e-255 847.7 0.0 6.1e-255 847.3 0.0 1.0 1 0 0 1 1 1 1 TH1 protein FMN_red PF03358.15 OWF50863.1 - 0.0049 16.6 0.1 0.68 9.7 0.0 3.0 3 0 0 3 3 3 1 NADPH-dependent FMN reductase VCBS PF13517.6 OWF50864.1 - 0.00036 21.1 0.4 0.24 12.0 0.0 3.9 4 0 0 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OWF50864.1 - 0.024 14.8 0.1 0.024 14.8 0.1 3.1 3 0 0 3 3 3 0 FG-GAP repeat CUB PF00431.20 OWF50865.1 - 2.1e-07 31.3 0.3 0.0092 16.3 0.0 2.8 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 OWF50865.1 - 7.6e-07 29.2 8.5 1.6e-06 28.2 8.5 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TMEM154 PF15102.6 OWF50865.1 - 0.042 13.8 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 OWF50865.1 - 0.11 12.5 1.6 0.22 11.5 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Endomucin PF07010.12 OWF50865.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.7 3 0 0 3 3 3 0 Endomucin Gemini_mov PF01708.16 OWF50865.1 - 0.2 11.4 0.2 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF4519 PF15012.6 OWF50865.1 - 0.31 11.2 4.1 0.8 9.9 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) CcmD PF04995.14 OWF50865.1 - 0.43 10.7 1.5 0.99 9.5 1.5 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) CENP-N PF05238.13 OWF50866.1 - 7.5e-26 91.4 0.5 1.3e-25 90.6 0.5 1.5 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Peptidase_M8 PF01457.16 OWF50867.1 - 7.3e-66 222.9 8.1 1.7e-65 221.7 5.6 2.4 2 1 0 2 2 2 1 Leishmanolysin SprT-like PF10263.9 OWF50867.1 - 0.06 13.2 0.0 0.96 9.3 0.0 2.3 2 0 0 2 2 2 0 SprT-like family BTB PF00651.31 OWF50868.1 - 5.4e-18 65.2 0.0 1.4e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 OWF50868.1 - 2.3e-17 62.4 138.1 0.013 15.9 0.2 15.7 16 0 0 16 16 16 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF50868.1 - 2.3e-14 52.8 128.4 0.0078 17.0 1.7 15.3 15 0 0 15 15 15 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF50868.1 - 2.2e-12 46.5 25.2 4.8e-06 26.2 0.3 8.6 9 0 0 9 9 9 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OWF50868.1 - 1e-05 25.7 14.1 0.00012 22.4 4.4 13.8 14 0 0 14 14 14 5 Zinc-finger double domain LMBR1 PF04791.16 OWF50868.1 - 1.4 7.7 5.3 2.3 7.0 5.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2_11 PF16622.5 OWF50868.1 - 1.6 8.6 45.3 0.12 12.1 0.3 8.8 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 OWF50868.1 - 3.1 8.5 67.2 1.4 9.6 1.5 9.4 3 2 4 9 9 9 0 Zinc finger C2H2-type, 3 repeats TPR_12 PF13424.6 OWF50869.1 - 1.5e-13 50.8 1.7 7.7e-06 26.1 0.0 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF50869.1 - 1.7e-09 37.5 0.0 7.2e-07 28.9 0.0 2.2 1 1 0 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 OWF50869.1 - 1.5e-08 35.0 1.8 0.0086 16.6 0.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF50869.1 - 3.1e-07 30.6 2.7 4.2 8.5 0.1 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF50869.1 - 1.3e-06 28.0 13.5 0.17 12.1 0.1 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF50869.1 - 3.9e-05 23.3 12.1 0.038 13.8 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF50869.1 - 0.00025 21.0 13.3 0.69 10.3 0.2 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF50869.1 - 0.0019 18.1 2.5 0.16 12.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF50869.1 - 0.002 17.9 0.5 31 4.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OWF50869.1 - 0.0046 17.0 0.1 0.016 15.3 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 5 PPR PF01535.20 OWF50869.1 - 0.016 15.4 4.4 38 4.9 0.1 4.6 4 0 0 4 4 4 0 PPR repeat TPR_17 PF13431.6 OWF50869.1 - 0.071 13.5 1.1 9.7 6.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat COBRA PF04833.15 OWF50869.1 - 0.14 12.1 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 COBRA-like protein AA_permease_2 PF13520.6 OWF50870.1 - 0.003 16.5 7.6 0.0036 16.2 7.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OWF50871.1 - 2e-49 168.6 28.9 2.5e-49 168.3 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF50871.1 - 7.8e-18 64.3 31.6 1.6e-17 63.3 31.6 1.5 1 1 0 1 1 1 1 Amino acid permease DUF4448 PF14610.6 OWF50871.1 - 1.3 8.7 5.0 5.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Scs3p PF10261.9 OWF50872.1 - 1.1e-26 93.9 14.4 9.4e-18 64.6 0.9 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 OWF50872.1 - 0.046 13.5 0.3 0.046 13.5 0.3 2.5 1 1 1 3 3 3 0 PAP2 superfamily DUF3139 PF11337.8 OWF50872.1 - 0.23 12.1 1.4 0.63 10.7 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) zf-H2C2_2 PF13465.6 OWF50873.1 - 1.1e-34 117.2 134.0 9e-07 29.0 0.5 19.3 19 1 0 19 19 18 12 Zinc-finger double domain zf-C2H2 PF00096.26 OWF50873.1 - 1.2e-29 101.1 167.6 0.00021 21.6 0.4 19.5 19 0 0 19 19 19 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF50873.1 - 2.2e-25 87.2 152.9 0.0082 16.9 2.7 19.5 19 0 0 19 19 19 13 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF50873.1 - 1.8e-09 37.2 125.5 4.8e-05 23.0 3.1 13.8 15 1 0 15 15 15 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 OWF50873.1 - 1.9e-07 31.2 96.7 0.16 12.3 0.3 14.2 15 0 0 15 15 14 9 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF50873.1 - 8.2e-07 28.9 9.2 2.3e-06 27.5 1.2 14.6 17 1 0 17 17 16 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OWF50873.1 - 0.012 15.9 2.3 0.012 15.9 2.3 14.1 5 2 9 16 16 16 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 OWF50873.1 - 0.015 14.9 0.8 0.015 14.9 0.8 12.5 10 3 5 15 15 14 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 OWF50873.1 - 0.067 13.7 0.0 0.067 13.7 0.0 14.4 11 3 3 14 14 13 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 OWF50873.1 - 0.25 11.2 8.7 6.2 6.7 0.7 5.0 4 1 1 5 5 5 0 GAGA factor zf-C2H2_7 PF15269.6 OWF50873.1 - 6.2 7.0 48.5 1 9.5 3.7 8.0 6 3 3 9 9 9 0 Zinc-finger Neurochondrin PF05536.11 OWF50874.1 - 1.6e-111 373.6 11.8 6.4e-86 289.0 3.4 2.1 2 0 0 2 2 2 2 Neurochondrin Xpo1 PF08389.12 OWF50874.1 - 0.017 15.2 0.2 0.017 15.2 0.2 2.8 3 0 0 3 3 3 0 Exportin 1-like protein RNase_PH PF01138.21 OWF50875.1 - 2.6e-34 118.6 0.0 3.6e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OWF50875.1 - 6e-06 26.2 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Lambda_CIII PF02061.16 OWF50875.1 - 0.033 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Lambda Phage CIII FAM92 PF06730.11 OWF50876.1 - 7.5e-67 225.0 10.6 1e-66 224.6 10.6 1.2 1 0 0 1 1 1 1 FAM92 protein BAR_3 PF16746.5 OWF50876.1 - 9.8e-07 28.7 12.7 1.7e-06 27.9 12.7 1.5 1 0 0 1 1 1 1 BAR domain of APPL family Vps5 PF09325.10 OWF50876.1 - 0.00025 20.7 18.3 0.00065 19.3 8.4 2.6 2 1 1 3 3 3 2 Vps5 C terminal like Dopey_N PF04118.14 OWF50876.1 - 0.0081 15.3 0.1 0.025 13.7 0.0 1.9 1 1 1 2 2 2 1 Dopey, N-terminal DUF4477 PF14780.6 OWF50876.1 - 0.13 11.9 3.3 0.2 11.2 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4477) DUF2203 PF09969.9 OWF50876.1 - 0.21 12.3 5.6 4.7 8.0 3.5 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Uteroglobin PF01099.17 OWF50876.1 - 1.6 9.1 7.5 11 6.5 0.2 3.0 3 1 1 4 4 4 0 Uteroglobin family Nucleo_P87 PF07267.11 OWF50876.1 - 4.2 6.1 26.0 1.5e+02 1.0 26.0 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 OWF50876.1 - 5.5 6.2 22.8 0.034 13.5 13.2 2.0 2 1 1 3 3 3 0 NOA36 protein DUF563 PF04577.14 OWF50877.1 - 2.2e-14 54.1 0.0 4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) ABC_trans_N PF14510.6 OWF50878.1 - 0.025 15.2 0.0 0.035 14.7 0.0 1.3 1 0 0 1 1 1 0 ABC-transporter N-terminal Pox_vIL-18BP PF05566.12 OWF50880.1 - 1.4 9.1 26.5 17 5.6 4.9 6.4 1 1 3 4 4 4 0 Orthopoxvirus interleukin 18 binding protein DUF724 PF05266.14 OWF50880.1 - 5.7 6.7 6.4 21 4.9 0.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF724) HMG_box PF00505.19 OWF50882.1 - 3.2e-17 62.7 0.5 6e-17 61.8 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF50882.1 - 4.8e-11 43.1 0.5 9.2e-11 42.2 0.5 1.4 1 0 0 1 1 1 1 HMG-box domain OrfB_Zn_ribbon PF07282.11 OWF50882.1 - 0.058 13.3 2.2 0.16 11.9 2.2 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YABBY PF04690.13 OWF50882.1 - 0.13 12.8 4.5 0.095 13.3 2.9 1.6 1 1 0 1 1 1 0 YABBY protein K_channel_TID PF07941.11 OWF50882.1 - 2 9.0 10.7 32 5.1 8.4 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SNF PF00209.18 OWF50883.1 - 2e-191 637.3 30.0 2.4e-191 637.0 30.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LRR_8 PF13855.6 OWF50884.1 - 9.5e-38 127.8 45.1 2.1e-08 33.8 1.3 9.4 7 2 2 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 OWF50884.1 - 1.2e-16 60.5 65.3 0.0012 19.2 2.5 11.4 6 3 6 13 13 13 9 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF50884.1 - 2.4e-16 60.0 0.2 6.1e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF50884.1 - 1.1e-15 58.3 0.1 4.8e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 OWF50884.1 - 0.00055 19.5 21.5 0.31 10.5 0.1 6.0 4 1 3 7 7 7 4 Leucine-rich repeat LRR_1 PF00560.33 OWF50884.1 - 0.0013 19.0 46.1 13 6.8 0.9 14.4 15 2 0 15 15 15 1 Leucine Rich Repeat LRRNT PF01462.18 OWF50884.1 - 0.064 12.9 0.1 0.19 11.4 0.1 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 OWF50884.1 - 0.075 13.1 53.3 1.7 8.9 0.1 14.0 16 0 0 16 16 16 0 Leucine Rich repeat DUF1077 PF06417.12 OWF50885.1 - 8.4e-46 154.8 2.6 1.1e-45 154.5 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) FA_hydroxylase PF04116.13 OWF50887.1 - 1.2e-15 58.0 10.5 1.2e-15 58.0 10.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 OWF50887.1 - 1.6e-14 53.8 2.0 3.4e-13 49.5 0.1 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Aa_trans PF01490.18 OWF50888.1 - 7.7e-17 61.1 22.2 3.9e-11 42.3 9.1 2.4 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OWF50888.1 - 2.6e-06 26.7 21.4 0.00017 20.8 6.7 2.4 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family FixQ PF05545.11 OWF50888.1 - 0.22 11.5 0.1 0.22 11.5 0.1 4.7 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ SMN PF06003.12 OWF50889.1 - 2 7.6 11.6 2.3 7.4 11.6 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TEX33 PF15400.6 OWF50890.1 - 2.2e-27 96.2 1.6 2.2e-27 96.2 1.6 1.7 2 0 0 2 2 2 1 Testis-expressed sequence 33 protein family 7tm_1 PF00001.21 OWF50891.1 - 1.1e-35 123.3 19.6 1.3e-35 123.0 19.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF50891.1 - 1.2e-08 34.7 19.8 1.4e-08 34.4 19.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF50891.1 - 9.4e-05 22.3 11.6 0.00082 19.2 11.6 2.2 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF50891.1 - 0.0036 17.0 20.3 0.0071 16.0 20.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Mad3_BUB1_I PF08311.12 OWF50892.1 - 3.1e-41 140.2 0.7 3.1e-41 140.2 0.7 2.3 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OWF50892.1 - 1.7e-11 44.0 2.7 2.4e-11 43.5 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 OWF50892.1 - 2.1e-06 27.9 0.1 6.3e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Kinase-like PF14531.6 OWF50892.1 - 0.0012 18.2 0.1 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF50892.1 - 0.074 11.8 12.0 24 3.5 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase Golgin_A5 PF09787.9 OWF50892.1 - 2 7.8 37.9 5.1 6.5 37.9 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 OWF50892.1 - 4.4 6.6 30.4 9.4 5.5 30.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IPK PF03770.16 OWF50893.1 - 8.2e-46 156.4 0.0 1.3e-45 155.7 0.0 1.3 1 1 0 1 1 1 1 Inositol polyphosphate kinase Pacifastin_I PF05375.13 OWF50896.1 - 0.0084 15.8 4.3 0.0084 15.8 4.3 1.9 2 0 0 2 2 2 1 Pacifastin inhibitor (LCMII) TILa PF12714.7 OWF50896.1 - 0.051 13.5 8.3 0.042 13.8 2.3 2.4 2 0 0 2 2 2 0 TILa domain TILa PF12714.7 OWF50897.1 - 1.4 9.0 10.4 0.37 10.8 1.3 2.5 2 0 0 2 2 2 0 TILa domain DUF3432 PF11914.8 OWF50898.1 - 5.2e-05 23.4 2.2 5.2e-05 23.4 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3432) DUF3368 PF11848.8 OWF50899.1 - 0.15 11.9 0.1 0.43 10.4 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3368) PerC PF06069.11 OWF50899.1 - 0.18 12.1 1.7 0.31 11.3 0.8 1.7 1 1 1 2 2 2 0 PerC transcriptional activator DUF4509 PF14970.6 OWF50899.1 - 0.34 10.8 4.8 3.9 7.4 5.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4509) Phage_GPO PF05929.11 OWF50899.1 - 0.4 10.2 3.1 0.59 9.7 3.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RAI1 PF08652.11 OWF50899.1 - 0.82 9.9 3.1 0.81 9.9 1.0 2.0 2 1 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease FapA PF03961.13 OWF50899.1 - 7 5.1 8.1 11 4.4 8.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Xylo_C PF12529.8 OWF50901.1 - 5.1e-49 166.4 0.2 7.7e-49 165.8 0.2 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 OWF50901.1 - 2.6e-36 125.4 0.6 3.7e-36 124.9 0.6 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WSC PF01822.19 OWF50901.1 - 1.7e-16 60.2 5.1 1.7e-16 60.2 5.1 1.8 2 0 0 2 2 2 1 WSC domain Mab-21 PF03281.14 OWF50902.1 - 8.4e-28 97.5 0.8 1.8e-27 96.4 0.8 1.5 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF50902.1 - 0.039 14.3 0.0 0.49 10.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MAPKK1_Int PF08923.10 OWF50903.1 - 1.4e-38 131.3 0.2 1.6e-38 131.1 0.2 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Apyrase PF06079.11 OWF50904.1 - 2e-125 417.9 4.5 2.3e-125 417.6 4.5 1.0 1 0 0 1 1 1 1 Apyrase Calcyon PF06387.11 OWF50904.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) AAL_decarboxy PF03306.13 OWF50904.1 - 0.045 13.1 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase SUB1_ProdP9 PF18213.1 OWF50904.1 - 0.32 10.9 1.1 1.1 9.2 0.9 2.0 1 1 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Ribosomal_L1 PF00687.21 OWF50905.1 - 1.2e-44 152.5 3.4 1.2e-44 152.5 3.4 2.3 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family TolB_N PF04052.13 OWF50905.1 - 0.0043 17.2 0.1 0.0098 16.1 0.1 1.6 1 0 0 1 1 1 1 TolB amino-terminal domain RINT1_TIP1 PF04437.13 OWF50906.1 - 4.5e-116 388.7 1.8 4.5e-116 388.7 1.8 2.4 2 2 0 2 2 2 1 RINT-1 / TIP-1 family Sec5 PF15469.6 OWF50906.1 - 0.0079 16.0 2.4 0.0079 16.0 2.4 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 DUF4763 PF15960.5 OWF50906.1 - 0.0086 15.4 0.5 0.025 13.9 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Syntaxin_2 PF14523.6 OWF50906.1 - 0.0092 16.3 8.5 0.012 16.0 2.1 3.1 2 1 1 3 3 3 1 Syntaxin-like protein TMF_TATA_bd PF12325.8 OWF50906.1 - 0.12 12.7 3.8 0.15 12.3 0.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 OWF50906.1 - 0.15 12.1 2.7 0.75 9.9 2.6 2.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec6 PF06046.13 OWF50906.1 - 0.16 10.3 7.7 0.026 12.9 1.6 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec6 CENP-F_leu_zip PF10473.9 OWF50906.1 - 0.19 11.7 4.8 0.07 13.1 1.5 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.13 OWF50906.1 - 0.29 10.7 3.7 0.35 10.4 1.5 2.3 2 0 0 2 2 2 0 fzo-like conserved region Sec8_exocyst PF04048.14 OWF50906.1 - 8.2 6.3 9.9 9.9 6.0 5.1 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DEAD PF00270.29 OWF50907.1 - 6.4e-09 35.8 0.0 4.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OWF50907.1 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ShK PF01549.24 OWF50908.1 - 1.6e-06 28.6 30.9 0.0061 17.1 8.0 3.1 3 0 0 3 3 3 3 ShK domain-like Ribosomal_S4 PF00163.19 OWF50909.1 - 1.6e-09 38.5 1.3 2.4e-09 38.0 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 OWF50909.1 - 2.3e-08 33.6 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ets PF00178.22 OWF50909.1 - 0.0073 16.8 2.9 0.6 10.6 2.1 2.6 2 1 0 2 2 2 2 Ets-domain EGF PF00008.27 OWF50910.1 - 5.7e-186 602.0 575.0 6.5e-09 35.9 7.6 37.3 36 0 0 36 36 36 35 EGF-like domain hEGF PF12661.7 OWF50910.1 - 2.6e-102 332.4 493.7 1.6e-06 28.5 5.0 38.4 37 0 0 37 37 35 33 Human growth factor-like EGF EGF_CA PF07645.15 OWF50910.1 - 4e-42 142.1 592.2 1e-07 32.0 8.6 37.3 23 11 15 38 38 34 26 Calcium-binding EGF domain Ank_2 PF12796.7 OWF50910.1 - 1.4e-25 89.7 4.3 3.5e-13 49.9 1.6 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) EGF_2 PF07974.13 OWF50910.1 - 9.8e-25 86.6 657.7 0.0013 19.1 9.9 38.4 38 1 0 38 38 37 27 EGF-like domain Notch PF00066.17 OWF50910.1 - 4.3e-24 84.7 51.7 5e-11 42.9 12.5 20.4 21 7 1 22 22 3 3 LNR domain Ank PF00023.30 OWF50910.1 - 3.1e-23 81.2 6.1 0.00018 21.8 0.4 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OWF50910.1 - 6.8e-23 80.4 6.3 1.8e-07 31.3 1.2 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) DUF3454 PF11936.8 OWF50910.1 - 1.1e-18 67.4 20.7 1.1e-18 67.4 20.7 3.7 3 1 0 3 3 1 1 Domain of unknown function (DUF3454) Ank_3 PF13606.6 OWF50910.1 - 1.5e-16 58.7 0.9 0.00071 19.8 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OWF50910.1 - 1.9e-16 60.2 0.4 0.00035 21.1 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) NOD PF06816.13 OWF50910.1 - 6.9e-14 51.2 0.1 1.2e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 NOTCH protein NODP PF07684.12 OWF50910.1 - 0.00015 21.9 0.0 0.00015 21.9 0.0 3.7 3 0 0 3 3 2 1 NOTCH protein Peptidase_C12 PF01088.21 OWF50911.1 - 2.4e-69 233.3 0.1 8.4e-69 231.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 OWF50911.1 - 1.4e-19 69.7 5.6 1.4e-19 69.7 5.6 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases zf-CDGSH PF09360.10 OWF50912.1 - 1.8e-16 60.1 7.3 1.2e-08 35.0 2.5 2.6 2 1 0 2 2 2 2 Iron-binding zinc finger CDGSH type NHL PF01436.21 OWF50913.1 - 4.4e-05 23.3 3.2 0.16 12.1 0.0 3.4 4 0 0 4 4 4 2 NHL repeat zf-B_box PF00643.24 OWF50913.1 - 0.00025 21.1 10.6 0.00063 19.8 10.6 1.7 1 0 0 1 1 1 1 B-box zinc finger Cor1 PF04803.12 OWF50913.1 - 0.01 16.1 6.1 0.024 14.8 6.1 1.6 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region ApoLp-III PF07464.11 OWF50913.1 - 0.036 14.1 6.3 0.061 13.4 4.3 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SGL PF08450.12 OWF50913.1 - 0.069 12.7 0.8 6.7 6.2 0.0 3.1 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Mitofilin PF09731.9 OWF50913.1 - 0.15 10.9 5.4 0.23 10.3 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Syntaxin-6_N PF09177.11 OWF50913.1 - 0.22 12.1 2.4 1.8 9.2 1.8 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 OWF50913.1 - 0.25 11.5 11.4 0.89 9.7 11.4 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 OWF50913.1 - 0.25 10.2 3.4 0.33 9.8 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Apolipoprotein PF01442.18 OWF50913.1 - 0.3 10.9 3.2 0.92 9.4 3.2 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ZYG-11_interact PF05884.12 OWF50913.1 - 0.31 10.4 0.3 0.42 10.0 0.3 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF4455 PF14643.6 OWF50913.1 - 0.31 9.6 9.2 0.28 9.8 4.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) DUF1664 PF07889.12 OWF50913.1 - 0.39 10.8 6.6 1.1 9.4 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sipho_Gp157 PF05565.11 OWF50913.1 - 0.42 10.6 8.7 0.6 10.1 0.7 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 ALMT PF11744.8 OWF50913.1 - 0.83 8.4 7.0 1.1 8.0 7.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Nup54 PF13874.6 OWF50913.1 - 1.3 9.1 4.1 1.4 9.1 2.9 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 BshC PF10079.9 OWF50913.1 - 1.4 7.6 5.7 1.9 7.1 5.7 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Med9 PF07544.13 OWF50913.1 - 2 8.5 9.8 4.7 7.4 0.5 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GldM_N PF12081.8 OWF50913.1 - 9.7 6.2 10.7 34 4.5 0.5 2.0 1 1 1 2 2 2 0 GldM N-terminal domain Sec1 PF00995.23 OWF50914.1 - 4.7e-121 405.8 0.2 5.6e-121 405.6 0.2 1.0 1 0 0 1 1 1 1 Sec1 family DUF5071 PF16804.5 OWF50914.1 - 0.013 15.7 1.2 1.1 9.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) RasGEF PF00617.19 OWF50915.1 - 6.1e-50 169.9 1.1 6.1e-50 169.9 1.1 4.2 5 0 0 5 5 5 1 RasGEF domain RasGEF_N PF00618.20 OWF50915.1 - 9.1e-07 29.1 0.0 5.2e-06 26.6 0.0 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF2533 PF10752.9 OWF50915.1 - 0.035 14.5 0.1 0.16 12.4 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) ATG16 PF08614.11 OWF50915.1 - 1.6 9.0 4.0 1.1 9.4 1.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) GDWWSH PF15667.5 OWF50916.1 - 0.0028 17.1 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function with motif GDWWSH NmrA PF05368.13 OWF50917.1 - 7.6e-10 38.7 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OWF50917.1 - 0.00016 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AlbA_2 PF04326.14 OWF50918.1 - 4.8e-09 36.6 0.0 1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Putative DNA-binding domain TUDOR PF00567.24 OWF50918.1 - 5.1e-06 26.5 0.1 4.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 Tudor domain REGB_T4 PF10715.9 OWF50918.1 - 0.04 14.1 0.1 0.09 13.0 0.1 1.6 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB Ric8 PF10165.9 OWF50918.1 - 0.051 12.6 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn NinB PF05772.12 OWF50918.1 - 0.079 12.8 2.4 4.7 7.0 0.0 2.7 3 0 0 3 3 3 0 NinB protein Proteasome PF00227.26 OWF50919.1 - 3e-50 170.4 0.1 3.5e-50 170.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit NAD_Gly3P_dh_C PF07479.14 OWF50919.1 - 0.099 12.9 0.1 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PAP2 PF01569.21 OWF50920.1 - 2e-21 76.2 3.1 3.2e-21 75.5 3.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OWF50920.1 - 1.8e-05 24.5 8.5 8e-05 22.4 8.5 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OWF50920.1 - 0.003 18.0 1.0 0.003 18.0 1.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal VirB8 PF04335.13 OWF50921.1 - 0.073 12.9 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 VirB8 protein Pkinase PF00069.25 OWF50922.1 - 7.9e-65 218.8 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF50922.1 - 5.8e-47 160.2 0.0 7.7e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF50922.1 - 8.2e-07 28.6 0.0 1.3e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF50922.1 - 1e-05 24.7 0.1 2e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OWF50922.1 - 1.7e-05 23.8 0.0 2.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF50922.1 - 0.002 17.5 0.2 0.0041 16.5 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF50922.1 - 0.0079 16.1 0.0 0.17 11.8 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF309 PF03745.14 OWF50922.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Nucleoporin_FG PF13634.6 OWF50923.1 - 2.6e-15 57.0 137.4 1.4e-09 38.6 34.6 16.0 4 3 11 15 15 15 5 Nucleoporin FG repeat region eIF2A PF08662.11 OWF50923.1 - 0.00083 19.3 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OWF50923.1 - 0.0093 16.3 0.0 0.25 11.7 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TolA_bind_tri PF16331.5 OWF50923.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.3 3 0 0 3 3 3 0 TolA binding protein trimerisation Troponin PF00992.20 OWF50923.1 - 0.18 12.1 2.8 0.39 11.0 0.4 2.3 2 0 0 2 2 2 0 Troponin CENP-B_dimeris PF09026.10 OWF50923.1 - 2.7 8.5 15.4 6.4 7.2 15.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_C14 PF00656.22 OWF50924.1 - 7.9e-14 52.2 0.0 1.2e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain TDP43_N PF18694.1 OWF50924.1 - 9.4e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain 2OG-FeII_Oxy PF03171.20 OWF50924.1 - 0.1 13.1 0.0 7.7 7.1 0.0 2.4 1 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily HEAT_2 PF13646.6 OWF50925.1 - 0.00032 21.0 0.0 0.00058 20.2 0.0 1.4 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 OWF50925.1 - 0.0019 18.3 0.0 0.98 9.9 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 OWF50926.1 - 1.1e-06 28.9 0.2 0.00049 20.4 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 OWF50926.1 - 1e-05 25.4 0.1 2.4 8.7 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 OWF50926.1 - 0.0073 16.4 0.1 0.027 14.5 0.1 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 OWF50926.1 - 0.02 14.8 1.0 0.39 10.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) V-ATPase_H_C PF11698.8 OWF50926.1 - 0.12 12.5 0.2 7.3 6.7 0.0 2.3 1 1 1 2 2 2 0 V-ATPase subunit H DUF1154 PF06631.11 OWF50927.1 - 0.025 14.6 0.8 0.053 13.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Bap31_Bap29_C PF18035.1 OWF50927.1 - 0.37 10.8 2.9 0.9 9.6 2.9 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain RhoGEF PF00621.20 OWF50928.1 - 1.1e-31 110.5 0.4 3e-31 109.1 0.4 1.8 1 0 0 1 1 1 1 RhoGEF domain DUF4347 PF14252.6 OWF50928.1 - 3.4e-11 43.3 0.0 9.2e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) F-box-like PF12937.7 OWF50928.1 - 1.2e-06 28.3 0.8 2.3e-06 27.4 0.8 1.5 1 0 0 1 1 1 1 F-box-like IQ_SEC7_PH PF16453.5 OWF50928.1 - 0.00076 19.5 0.1 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 PH domain F-box PF00646.33 OWF50928.1 - 0.0013 18.5 0.1 0.0058 16.5 0.1 2.1 1 1 1 2 2 2 1 F-box domain Dpy-30 PF05186.13 OWF50928.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif DUF4508 PF14969.6 OWF50928.1 - 0.012 15.8 7.1 0.081 13.2 1.5 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4508) Sec8_exocyst PF04048.14 OWF50928.1 - 0.05 13.5 0.1 4.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF2856 PF11043.8 OWF50928.1 - 0.071 13.2 1.6 5.9 7.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) QIL1 PF15884.5 OWF50928.1 - 0.12 13.0 0.0 0.58 10.8 0.0 2.3 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 PA26 PF04636.13 OWF50929.1 - 4.5e-193 642.1 3.3 5.2e-193 641.9 3.3 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 OWF50929.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Sugar_tr PF00083.24 OWF50930.1 - 4.3e-31 108.3 13.7 4.3e-31 108.3 13.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF50930.1 - 3.7e-28 98.5 47.2 3.6e-25 88.6 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF50931.1 - 1.8e-28 99.7 17.0 1.8e-28 99.7 17.0 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF50931.1 - 2.9e-25 89.0 34.4 4.5e-18 65.3 7.5 2.4 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF50932.1 - 7.2e-24 84.5 21.7 9e-24 84.1 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF50932.1 - 5.3e-22 78.2 25.8 5.3e-22 78.2 25.8 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF3433 PF11915.8 OWF50932.1 - 0.72 10.4 10.4 0.044 14.2 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Yae1_N PF09811.9 OWF50933.1 - 9.4e-06 25.2 5.7 1.9e-05 24.3 5.7 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SMAP PF15477.6 OWF50934.1 - 4.8e-12 46.7 0.9 4.8e-12 46.7 0.9 2.0 2 0 0 2 2 2 1 Small acidic protein family Glyco_transf_7N PF13733.6 OWF50935.1 - 4.3e-46 155.9 0.1 7e-46 155.2 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF50935.1 - 1.9e-19 69.0 0.0 3.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4293 PF14126.6 OWF50935.1 - 0.051 13.8 0.2 0.08 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) SYF2 PF08231.12 OWF50936.1 - 1.2e-53 181.8 15.8 1.2e-53 181.8 15.8 2.5 1 1 1 2 2 2 1 SYF2 splicing factor Ribosomal_S30AE PF02482.19 OWF50936.1 - 0.23 12.2 0.1 0.23 12.2 0.1 3.1 3 1 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein HU-CCDC81_euk_1 PF14908.6 OWF50937.1 - 6.3e-27 93.6 0.5 1.7e-26 92.2 0.5 1.8 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 OWF50937.1 - 6.7e-27 93.5 0.1 5.9e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 OWF50937.1 - 1.2e-05 25.4 2.3 0.0023 18.1 0.1 2.9 3 0 0 3 3 3 2 Bacterial DNA-binding protein HU-HIG PF18291.1 OWF50937.1 - 0.053 13.6 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif SwrA PF17423.2 OWF50938.1 - 0.035 14.1 0.2 0.041 13.9 0.2 1.1 1 0 0 1 1 1 0 Swarming motility protein Arm PF00514.23 OWF50939.1 - 7.5e-90 292.6 16.7 2.7e-12 46.3 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 OWF50939.1 - 1.4e-24 85.4 0.7 1.3e-23 82.3 1.4 2.2 3 0 0 3 3 3 1 Atypical Arm repeat IBB PF01749.20 OWF50939.1 - 1.4e-24 86.3 1.4 2.8e-24 85.4 1.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 OWF50939.1 - 2.9e-21 75.7 0.0 2.8e-06 27.6 0.0 4.8 2 1 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 OWF50939.1 - 3.3e-21 75.4 2.4 0.00029 21.3 0.1 6.5 5 1 1 6 6 6 3 HEAT-like repeat HEAT PF02985.22 OWF50939.1 - 1.6e-15 55.9 6.8 0.018 15.3 0.0 7.9 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.13 OWF50939.1 - 6.7e-07 29.0 0.1 0.0028 17.2 0.1 3.4 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 OWF50939.1 - 6.7e-05 21.6 0.1 0.73 8.3 0.0 3.2 2 1 0 3 3 3 2 Adaptin N terminal region RICTOR_V PF14668.6 OWF50939.1 - 9.9e-05 22.5 0.6 0.79 10.0 0.0 4.9 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 OWF50939.1 - 0.00019 21.6 0.3 0.26 11.4 0.1 3.6 3 2 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 OWF50939.1 - 0.0034 17.9 0.1 3.8 8.5 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 OWF50939.1 - 0.0096 15.5 0.1 13 5.3 0.0 3.9 1 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 OWF50939.1 - 0.0098 15.9 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 OWF50939.1 - 0.084 12.8 0.9 11 5.9 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) CTNNBL PF08216.11 OWF50939.1 - 0.12 12.5 0.0 4.2 7.6 0.0 3.6 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear NUSAP PF16006.5 OWF50939.1 - 0.13 12.0 4.5 0.18 11.5 4.5 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein Cid2 PF09774.9 OWF50940.1 - 3.8e-13 50.2 0.3 2.4e-11 44.3 0.3 2.1 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Peptidase_C78 PF07910.13 OWF50941.1 - 2.3e-59 200.4 0.1 4.3e-59 199.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 OWF50941.1 - 1.1e-12 48.1 15.5 0.032 14.5 0.1 5.7 5 1 1 6 6 5 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OWF50941.1 - 9.4e-11 41.6 12.7 0.097 13.2 0.2 5.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF50941.1 - 6.2e-10 39.1 12.8 0.045 14.6 0.2 6.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 OWF50941.1 - 7.9e-08 32.4 11.6 0.24 11.9 0.1 5.6 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 OWF50941.1 - 1.9e-05 24.3 3.2 0.045 13.5 0.0 4.5 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 OWF50941.1 - 0.00024 21.4 11.6 0.088 13.2 0.4 4.8 3 2 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OWF50941.1 - 0.00048 20.3 9.1 0.34 11.3 0.0 5.5 6 0 0 6 6 5 1 Zinc-finger double-stranded RNA-binding zf_C2H2_10 PF18414.1 OWF50941.1 - 0.0036 16.8 13.2 0.088 12.4 0.1 4.5 4 0 0 4 4 4 2 C2H2 type zinc-finger Peptidase_C54 PF03416.19 OWF50941.1 - 0.043 13.2 0.6 0.14 11.6 0.4 1.8 1 1 1 2 2 2 0 Peptidase family C54 Rtf2 PF04641.12 OWF50941.1 - 0.11 11.9 10.0 0.98 8.7 1.6 2.5 2 1 0 2 2 2 0 Rtf2 RING-finger zf_Hakai PF18408.1 OWF50941.1 - 0.23 11.2 1.5 14 5.4 0.1 3.3 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain AKAP95 PF04988.12 OWF50941.1 - 0.59 10.3 3.4 3.8 7.7 0.0 3.5 3 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) Elf1 PF05129.13 OWF50941.1 - 1.6 8.8 8.1 8 6.6 0.5 4.0 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like DUF1178 PF06676.11 OWF50941.1 - 1.9 8.9 14.8 1 9.8 0.4 3.3 3 2 2 5 5 3 0 Protein of unknown function (DUF1178) zf-C2H2_9 PF16293.5 OWF50941.1 - 2 8.3 12.8 6 6.8 0.2 4.3 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 OWF50941.1 - 2.5 8.8 9.6 9.9 6.9 1.7 3.7 2 2 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-CHCC PF10276.9 OWF50941.1 - 6.6 6.9 9.1 73 3.5 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger domain zf-H2C2_2 PF13465.6 OWF50941.1 - 7 7.3 15.7 23 5.6 0.1 4.9 5 0 0 5 5 4 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 OWF50941.1 - 7.6 6.3 9.3 52 3.6 0.0 4.7 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain BIR PF00653.21 OWF50941.1 - 9.6 6.9 8.0 10 6.9 0.1 3.7 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain DUF3504 PF12012.8 OWF50942.1 - 7.8e-66 221.0 4.3 7.8e-66 221.0 4.3 4.9 5 1 2 7 7 7 1 Domain of unknown function (DUF3504) zf-FCS PF06467.14 OWF50942.1 - 4.3e-13 49.0 78.1 1.2e-07 31.6 5.5 8.9 8 0 0 8 8 8 6 MYM-type Zinc finger with FCS sequence motif RRM_1 PF00076.22 OWF50943.1 - 4.7e-30 103.2 0.1 8.6e-15 54.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 OWF50943.1 - 9.5e-23 80.1 4.6 2.6e-22 78.8 4.6 1.8 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 OWF50943.1 - 0.022 14.9 0.0 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif DUF4337 PF14235.6 OWF50943.1 - 0.88 9.7 2.8 1.6 8.8 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LPD25 PF18840.1 OWF50944.1 - 0.066 13.8 0.3 0.13 12.8 0.3 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 Ank_2 PF12796.7 OWF50945.1 - 2.2e-39 133.9 2.0 5.4e-10 39.7 0.0 5.8 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50945.1 - 3.3e-35 120.0 4.1 1.6e-05 25.4 0.0 9.6 7 2 3 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF50945.1 - 9.9e-28 95.9 11.7 1.1e-05 25.6 0.3 7.5 6 1 0 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF50945.1 - 2.7e-25 87.7 8.0 0.0021 18.4 0.0 10.7 11 0 0 11 11 11 7 Ankyrin repeat Ank_3 PF13606.6 OWF50945.1 - 1e-18 65.5 6.1 0.29 11.8 0.0 9.9 10 0 0 10 10 10 4 Ankyrin repeat Mab-21 PF03281.14 OWF50945.1 - 1.2e-08 34.7 0.0 0.002 17.5 0.1 2.6 2 0 0 2 2 2 2 Mab-21 protein Imm41 PF15592.6 OWF50945.1 - 0.018 15.4 0.0 0.067 13.5 0.0 2.0 1 0 0 1 1 1 0 Immunity protein 41 DUF2315 PF10231.9 OWF50946.1 - 0.57 10.3 6.6 0.063 13.4 2.1 1.8 2 1 0 2 2 2 0 Apoptogenic protein 1 NHL PF01436.21 OWF50947.1 - 1.8e-24 84.4 2.8 1.8e-06 27.7 0.0 5.4 5 0 0 5 5 5 4 NHL repeat SGL PF08450.12 OWF50947.1 - 0.00016 21.3 0.0 0.32 10.6 0.0 3.1 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 OWF50947.1 - 0.00038 19.7 0.8 0.0011 18.2 0.5 2.0 1 1 0 1 1 1 1 6-bladed beta-propeller C2 PF00168.30 OWF50951.1 - 6.9e-54 180.5 0.5 4.6e-27 94.3 0.1 2.6 3 0 0 3 3 3 2 C2 domain TMEM52 PF14979.6 OWF50951.1 - 8.8e-05 22.5 3.2 0.00016 21.6 3.2 1.4 1 0 0 1 1 1 1 Transmembrane 52 DOCK-C2 PF14429.6 OWF50951.1 - 0.0076 16.1 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins PI3K_C2 PF00792.24 OWF50951.1 - 0.01 15.8 0.0 0.065 13.2 0.0 2.4 3 0 0 3 3 3 0 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 OWF50951.1 - 0.028 14.0 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 CEP76 C2 domain Alpha_GJ PF03229.13 OWF50951.1 - 0.062 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J EphA2_TM PF14575.6 OWF50951.1 - 0.13 13.1 0.0 0.32 11.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HECT PF00632.25 OWF50952.1 - 6.4e-88 295.2 0.0 1.3e-87 294.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 OWF50952.1 - 2.3e-28 98.6 8.3 7.5e-14 52.1 0.9 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF50952.1 - 1.8e-27 95.3 8.8 1.9e-08 34.7 1.1 5.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF50952.1 - 3.7e-22 76.0 7.0 1.6e-05 24.9 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OWF50952.1 - 2.4e-21 75.5 9.4 3.6e-06 27.1 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF50952.1 - 5.2e-21 74.1 10.7 2.4e-05 24.5 0.4 5.6 5 0 0 5 5 5 4 Ankyrin repeat TraI_2 PF07514.11 OWF50952.1 - 0.16 10.9 0.5 9.9 5.0 0.0 2.5 2 0 0 2 2 2 0 Putative helicase Frizzled PF01534.17 OWF50953.1 - 4.7e-129 430.1 19.6 7.7e-129 429.4 19.6 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 OWF50953.1 - 5.5e-31 107.5 1.1 1.2e-30 106.4 1.1 1.6 1 0 0 1 1 1 1 Fz domain Oxidored_q2 PF00420.24 OWF50953.1 - 0.064 12.9 0.3 0.24 11.1 0.3 1.9 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TMEM135_C_rich PF15982.5 OWF50954.1 - 1.3e-50 171.4 1.0 1.3e-50 171.4 1.0 2.2 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 OWF50954.1 - 2e-06 28.1 0.5 4.7e-06 26.9 0.5 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DiS_P_DiS PF06750.13 OWF50954.1 - 0.0096 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Profilin PF00235.19 OWF50956.1 - 1.6e-18 67.2 0.0 2.1e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Profilin GST_C_2 PF13410.6 OWF50957.1 - 3.8e-07 30.0 0.0 7.8e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF50957.1 - 5.7e-06 26.5 0.0 1.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF50957.1 - 3.1e-05 24.1 0.0 6.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NPP PF08384.10 OWF50958.1 - 0.67 10.1 10.4 21 5.3 0.2 5.0 4 2 2 6 6 6 0 Pro-opiomelanocortin, N-terminal region zf-WRNIP1_ubi PF18279.1 OWF50958.1 - 2.9 8.7 15.9 50 4.9 0.1 6.2 7 0 0 7 7 7 0 Werner helicase-interacting protein 1 ubiquitin-binding domain TPR_2 PF07719.17 OWF50959.1 - 7.5e-08 31.9 17.2 0.038 14.1 0.4 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF50959.1 - 1.8e-06 28.1 14.5 0.018 15.3 0.2 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF50959.1 - 1.9e-06 27.4 21.4 0.0094 15.7 0.8 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OWF50959.1 - 3.3e-06 26.7 0.2 0.91 9.7 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF50959.1 - 1.3e-05 25.7 1.2 11 7.1 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF50959.1 - 0.00027 20.5 0.0 0.098 12.4 0.0 3.9 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 OWF50959.1 - 0.0021 18.2 11.8 2.7 8.5 0.2 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF50959.1 - 0.0048 16.9 0.7 0.22 11.6 0.3 3.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 OWF50959.1 - 0.0084 16.6 7.9 0.27 11.8 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat RPN7 PF10602.9 OWF50959.1 - 0.14 11.9 2.2 3.3 7.4 0.0 3.3 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 OWF50959.1 - 0.23 11.4 8.2 0.48 10.4 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF50959.1 - 0.85 10.2 5.6 2e+02 2.7 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF50959.1 - 4 7.7 19.4 4.2 7.7 2.2 5.7 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 LSM PF01423.22 OWF50960.1 - 5e-11 42.1 0.2 5e-11 42.1 0.2 1.8 2 1 0 2 2 2 1 LSM domain Homeodomain PF00046.29 OWF50961.1 - 6.9e-20 70.6 5.2 1.3e-19 69.8 5.2 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF50961.1 - 0.0036 16.7 0.2 0.0068 15.9 0.2 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF50961.1 - 0.015 15.2 0.2 0.037 13.9 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 OWF50961.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Auxin_canalis PF05703.11 OWF50961.1 - 1.3 8.9 3.9 2 8.3 3.9 1.2 1 0 0 1 1 1 0 Auxin canalisation Transferrin PF00405.17 OWF50962.1 - 7.6e-137 455.9 0.9 7.3e-68 229.1 0.1 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 OWF50962.1 - 6e-18 65.3 0.0 8.1e-09 35.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3421 PF11901.8 OWF50962.1 - 0.13 12.2 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) Ig_3 PF13927.6 OWF50963.1 - 1.8e-15 57.3 0.0 3.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF50963.1 - 3.8e-13 49.3 0.0 7.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF50963.1 - 5.1e-11 42.8 0.0 1.2e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 OWF50963.1 - 4e-06 26.9 0.0 7.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 OWF50963.1 - 5.2e-06 26.6 0.2 0.04 14.1 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF50963.1 - 0.027 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 OWF50963.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 C17orf99 Ig domain Acetyltransf_19 PF18015.1 OWF50964.1 - 0.00014 22.0 1.1 4.3 7.6 0.0 4.7 1 1 4 5 5 5 2 Acetyltransferase (GNAT) domain HHH_2 PF12826.7 OWF50964.1 - 0.067 13.3 1.0 36 4.6 0.0 4.4 4 0 0 4 4 4 0 Helix-hairpin-helix motif DUF928 PF06051.12 OWF50964.1 - 0.28 11.0 1.6 0.77 9.6 0.5 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF928) Ntox22 PF15527.6 OWF50964.1 - 0.55 10.3 1.6 48 4.0 0.1 3.0 1 1 3 4 4 4 0 Bacterial toxin 22 DUF5613 PF18467.1 OWF50964.1 - 1.6 9.2 11.5 31 5.1 0.2 5.0 3 1 1 6 6 6 0 Domain of unknown function (DUF5613) DUF4898 PF16239.5 OWF50964.1 - 9.7 6.2 19.5 27 4.8 0.5 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4898) Pax7 PF12360.8 OWF50965.1 - 1e-09 38.4 43.8 0.052 13.7 0.7 9.7 1 1 11 12 12 12 7 Paired box protein 7 AP_endonuc_2_N PF07582.12 OWF50965.1 - 2.9e-06 26.9 0.2 29 4.5 0.0 7.1 2 2 5 8 8 8 0 AP endonuclease family 2 C terminus AbrB PF05145.12 OWF50965.1 - 0.0018 17.3 0.6 3.1 6.7 0.0 2.8 2 1 1 3 3 3 2 Transition state regulatory protein AbrB DUF1132 PF06575.12 OWF50965.1 - 0.0028 18.0 4.7 43 4.6 0.1 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1132) TPP_enzyme_N PF02776.18 OWF50965.1 - 0.021 14.5 0.2 4.4 6.9 0.0 2.7 1 1 2 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Pox_A8 PF04745.12 OWF50965.1 - 0.051 12.7 0.3 16 4.4 0.0 3.1 1 1 1 3 3 3 0 VITF-3 subunit protein IL12 PF03039.14 OWF50965.1 - 2.6 7.3 15.5 4.2 6.7 0.4 4.0 1 1 5 6 6 6 0 Interleukin-12 alpha subunit YliH PF10799.8 OWF50965.1 - 8.6 6.3 39.0 12 5.8 0.2 10.1 1 1 7 10 10 10 0 Biofilm formation protein (YliH/bssR) Sec63 PF02889.16 OWF50966.1 - 7e-175 579.2 8.5 1.8e-94 315.7 0.9 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OWF50966.1 - 5.9e-53 179.2 0.1 1.2e-25 90.3 0.2 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OWF50966.1 - 1.3e-35 121.9 0.2 1.3e-35 121.9 0.2 2.5 3 0 0 3 3 3 1 N-terminal helicase PWI domain ResIII PF04851.15 OWF50966.1 - 2.6e-25 89.4 0.0 6e-12 45.9 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OWF50966.1 - 2.5e-17 63.2 0.1 6.7e-08 32.9 0.0 4.5 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 OWF50966.1 - 4.1e-08 33.2 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OWF50966.1 - 1.1e-06 29.0 0.1 0.007 16.6 0.1 3.8 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 OWF50966.1 - 0.0025 17.3 0.0 1.9 7.9 0.0 3.0 2 0 0 2 2 2 2 PhoH-like protein T2SSE PF00437.20 OWF50966.1 - 0.0044 16.1 0.0 1 8.4 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 OWF50966.1 - 0.012 15.3 0.0 0.077 12.7 0.0 2.3 2 0 0 2 2 2 0 SWI2/SNF2 ATPase AAA_7 PF12775.7 OWF50966.1 - 0.021 14.4 0.0 0.93 9.0 0.0 3.2 3 0 0 3 3 3 0 P-loop containing dynein motor region 5_nucleotid PF05761.14 OWF50967.1 - 3.8e-176 586.5 1.2 4.4e-176 586.3 1.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 OWF50967.1 - 0.09 12.9 0.0 21 5.2 0.0 3.3 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 OWF50968.1 - 7e-23 80.2 7.8 1.1e-22 79.7 7.8 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF50968.1 - 0.0083 15.6 0.2 0.016 14.7 0.2 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF50968.1 - 0.021 14.8 2.9 0.022 14.6 1.1 2.2 2 1 0 2 2 2 0 Homeobox KN domain Spond_N PF06468.13 OWF50969.1 - 4.2e-65 219.5 0.1 5.3e-65 219.1 0.1 1.1 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 OWF50969.1 - 9.9e-10 38.5 5.3 2.1e-09 37.4 5.3 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain zf-RRPl_C4 PF17026.5 OWF50970.1 - 0.013 15.6 0.3 0.02 15.0 0.3 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF1133 PF06576.11 OWF50970.1 - 0.079 12.3 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Tetraspanin PF00335.20 OWF50970.1 - 1.7 8.3 5.6 0.77 9.4 3.1 1.5 1 1 1 2 2 2 0 Tetraspanin family PAN_1 PF00024.26 OWF50971.1 - 2.4e-16 59.5 17.9 5.3e-09 35.9 3.1 3.2 3 0 0 3 3 3 2 PAN domain Lectin_C PF00059.21 OWF50971.1 - 1.6e-15 57.8 1.3 1.6e-15 57.8 1.3 2.4 2 0 0 2 2 2 1 Lectin C-type domain PAN_4 PF14295.6 OWF50971.1 - 0.034 14.0 5.1 0.067 13.1 0.8 3.2 2 0 0 2 2 2 0 PAN domain DUF3439 PF11921.8 OWF50971.1 - 0.67 9.9 19.3 0.13 12.3 14.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 OWF50971.1 - 3.1 7.8 22.2 2.5 8.1 13.9 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Homeodomain PF00046.29 OWF50972.1 - 2.8e-20 71.9 6.2 5.1e-20 71.1 6.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF50972.1 - 0.049 13.5 0.4 0.15 12.0 0.4 1.9 1 0 0 1 1 1 0 Homeobox KN domain Ion_trans PF00520.31 OWF50973.1 - 4.3e-05 22.9 3.1 4.3e-05 22.9 3.1 1.5 2 0 0 2 2 2 1 Ion transport protein LSDAT_euk PF18139.1 OWF50974.1 - 5.6e-26 91.5 0.1 1.3e-25 90.3 0.1 1.6 1 1 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 OWF50974.1 - 1.1e-11 44.4 0.0 7.5e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 SLOG in TRPM, prokaryote LuxT_C PF18285.1 OWF50974.1 - 0.06 13.9 0.1 0.2 12.2 0.1 2.0 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain FNIP_M PF14637.6 OWF50974.1 - 0.083 12.9 0.5 0.2 11.6 0.5 1.6 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Ank_2 PF12796.7 OWF50974.1 - 0.15 12.7 0.1 5.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) MFS_1 PF07690.16 OWF50975.1 - 3.9e-22 78.7 66.3 1.2e-21 77.1 40.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OWF50976.1 - 1.7e-25 89.7 46.1 6.2e-22 78.0 34.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YiaAB PF05360.14 OWF50976.1 - 0.025 14.8 0.2 0.025 14.8 0.2 5.9 7 1 0 7 7 7 0 yiaA/B two helix domain Xan_ur_permease PF00860.20 OWF50977.1 - 1.6e-49 168.7 13.8 2.2e-49 168.2 13.8 1.2 1 0 0 1 1 1 1 Permease family FAM70 PF14967.6 OWF50977.1 - 0.33 10.4 2.0 0.6 9.5 2.0 1.4 1 0 0 1 1 1 0 FAM70 protein DUF2231 PF09990.9 OWF50977.1 - 0.55 10.7 3.9 0.3 11.5 1.1 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) MFS_MOT1 PF16983.5 OWF50977.1 - 0.69 10.3 10.0 0.16 12.4 5.8 2.2 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 OWF50978.1 - 2.8e-37 128.4 12.2 3.8e-37 127.9 12.2 1.0 1 0 0 1 1 1 1 Permease family Sulfotransfer_1 PF00685.27 OWF50979.1 - 1.2e-14 54.4 0.2 2.8e-14 53.2 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF50979.1 - 2e-12 48.0 0.0 1.3e-11 45.3 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Halogen_Hydrol PF10112.9 OWF50979.1 - 0.09 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YlbD_coat PF14071.6 OWF50979.1 - 0.26 11.6 2.8 0.68 10.2 2.8 1.7 1 0 0 1 1 1 0 Putative coat protein Prominin PF05478.11 OWF50982.1 - 1.9e-163 545.5 4.2 2.3e-163 545.2 4.2 1.0 1 0 0 1 1 1 1 Prominin Cyt_bd_oxida_II PF02322.15 OWF50982.1 - 0.0055 16.1 2.6 1.2 8.4 0.2 2.4 2 0 0 2 2 2 2 Cytochrome bd terminal oxidase subunit II Oxidored_q3 PF00499.20 OWF50982.1 - 0.0081 15.9 2.4 1.6 8.4 0.6 2.5 2 0 0 2 2 2 2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Flavi_NS4A PF01350.17 OWF50982.1 - 0.033 14.1 2.4 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF1664 PF07889.12 OWF50982.1 - 0.083 12.9 4.5 8 6.5 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF3824 PF12868.7 OWF50982.1 - 0.11 13.1 6.0 0.23 12.1 6.0 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF16 PF01519.16 OWF50982.1 - 0.16 12.5 3.8 3.8 8.0 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function DUF16 Agglutinin PF07468.11 OWF50984.1 - 9.3e-11 42.2 6.9 14 5.8 0.0 11.6 1 1 14 15 15 15 1 Agglutinin domain Ribosomal_L19 PF01245.20 OWF50984.1 - 3.3e-07 30.2 13.9 33 4.5 0.0 9.0 1 1 9 12 12 12 0 Ribosomal protein L19 Fucose_iso_N2 PF07882.12 OWF50984.1 - 0.00019 21.1 2.3 15 5.2 0.0 6.0 2 2 6 8 8 8 2 L-fucose isomerase, second N-terminal domain DnaB_bind PF10410.9 OWF50984.1 - 0.0025 17.9 14.4 1.7e+02 2.5 0.0 11.5 12 3 2 16 16 16 0 DnaB-helicase binding domain of primase She2p PF11435.8 OWF50984.1 - 0.04 13.6 20.7 14 5.3 0.6 7.8 1 1 6 9 9 9 0 RNA binding protein She2p Methyltransf_4 PF02390.17 OWF50984.1 - 0.1 12.1 28.0 2.1 7.8 0.2 8.1 1 1 10 11 11 11 0 Putative methyltransferase DUF2974 PF11187.8 OWF50984.1 - 0.23 11.0 8.2 12 5.3 0.0 5.0 1 1 4 5 5 5 0 Protein of unknown function (DUF2974) Homeodomain PF00046.29 OWF50985.1 - 1.5e-21 75.9 5.2 2.3e-21 75.4 5.2 1.3 1 0 0 1 1 1 1 Homeodomain Allantoicase PF03561.15 OWF50986.1 - 1.8e-94 313.3 0.0 3.8e-49 166.4 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat NiFe_hyd_SSU_C PF14720.6 OWF50986.1 - 0.018 15.4 0.1 2.7 8.4 0.0 3.0 3 0 0 3 3 3 0 NiFe/NiFeSe hydrogenase small subunit C-terminal LPD18 PF18832.1 OWF50987.1 - 1.1e-05 25.3 20.4 0.63 10.2 1.3 8.7 2 2 3 6 6 6 4 Large polyvalent protein-associated domain 18 Fascin PF06268.13 OWF50987.1 - 0.083 13.1 0.0 33 4.7 0.0 3.9 2 2 1 4 4 4 0 Fascin domain Prot_ATP_ID_OB PF16450.5 OWF50987.1 - 0.1 12.6 14.9 3.8e+02 1.1 7.9 6.7 2 1 1 3 3 3 0 Proteasomal ATPase OB C-terminal domain TLP1_add_C PF18313.1 OWF50987.1 - 0.15 12.0 1.8 5.3 7.0 0.0 3.9 3 2 3 6 6 6 0 Thiolase-like protein type 1 additional C-terminal domain Cag12 PF13117.6 OWF50987.1 - 6.6 7.3 5.4 99 3.6 0.1 4.3 4 1 0 4 4 4 0 Cag pathogenicity island protein Cag12 Glyoxalase PF00903.25 OWF50988.1 - 4e-08 33.5 0.0 2.3e-05 24.6 0.0 2.8 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OWF50988.1 - 1.2e-06 28.8 0.0 0.0028 17.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AIG1 PF04548.16 OWF50989.1 - 3.4e-16 59.2 0.8 3.4e-16 59.2 0.8 3.7 1 1 2 3 3 3 1 AIG1 family TFIIA PF03153.13 OWF50989.1 - 0.4 10.6 38.6 0.54 10.2 38.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C1q PF00386.21 OWF50990.1 - 6.6e-18 65.1 0.4 1.1e-17 64.4 0.1 1.6 2 0 0 2 2 2 1 C1q domain TMF_DNA_bd PF12329.8 OWF50990.1 - 0.033 14.2 6.5 0.062 13.3 6.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BclA_C PF18573.1 OWF50990.1 - 0.076 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 BclA C-terminal domain IFT20 PF14931.6 OWF50990.1 - 0.13 12.5 6.0 0.19 11.9 6.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 HIP1_clath_bdg PF16515.5 OWF50990.1 - 0.26 11.9 6.3 0.43 11.2 5.6 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cep57_MT_bd PF06657.13 OWF50990.1 - 0.43 11.1 7.8 0.16 12.4 1.4 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 bZIP_1 PF00170.21 OWF50990.1 - 1.6 8.9 7.1 6 7.1 0.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor CH_2 PF06294.11 OWF50991.1 - 1.2e-30 105.5 0.7 3.2e-30 104.1 0.1 1.9 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OWF50991.1 - 5.1e-15 55.1 0.0 9.3e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 OWF50991.1 - 3.6e-05 23.9 0.5 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 OWF50992.1 - 8.7e-29 99.5 0.0 1.5e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OWF50992.1 - 2.3e-14 53.0 0.0 6.6e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 CAMSAP CH domain PKcGMP_CC PF16808.5 OWF50992.1 - 0.065 13.1 1.3 0.065 13.1 1.3 2.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase 2OG-FeII_Oxy_5 PF13759.6 OWF50993.1 - 2.2 8.8 15.0 3.3 8.2 15.0 1.4 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sulfotransfer_2 PF03567.14 OWF50994.1 - 1.9e-27 96.8 4.3 2.2e-26 93.3 3.0 2.1 2 0 0 2 2 2 2 Sulfotransferase family Period_C PF12114.8 OWF50997.1 - 0.19 11.3 0.1 29 4.2 0.1 3.6 2 2 1 4 4 4 0 Period protein 2/3C-terminal region pPIWI_RE_REase PF18154.1 OWF50998.1 - 0.034 14.1 0.1 54 3.8 0.0 3.6 2 1 2 4 4 4 0 REase associating with pPIWI_RE RGS12_usC PF16612.5 OWF50998.1 - 1.5 9.3 8.1 4.5 7.7 0.6 2.5 1 1 1 3 3 3 0 C-terminal unstructured region of RGS12 DUF4998 PF16389.5 OWF50998.1 - 4.7 6.8 6.9 10 5.7 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function pPIWI_RE_REase PF18154.1 OWF50999.1 - 1.1e-05 25.4 6.1 24 4.9 0.0 8.1 4 4 5 10 10 10 3 REase associating with pPIWI_RE AcetylCoA_hyd_C PF13336.6 OWF50999.1 - 0.78 9.7 29.1 1.1 9.2 0.2 6.9 1 1 4 7 7 7 0 Acetyl-CoA hydrolase/transferase C-terminal domain Peptidase_M10 PF00413.24 OWF51000.1 - 3.5e-37 127.7 0.1 6.5e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 OWF51000.1 - 9e-12 44.7 22.2 0.00048 20.0 0.5 4.7 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 OWF51000.1 - 1.1e-06 28.8 0.1 1.6e-05 25.0 0.1 2.5 1 1 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 OWF51000.1 - 0.0036 17.0 0.0 0.25 10.9 0.0 2.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Metallopep PF12044.8 OWF51000.1 - 0.0062 15.2 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family PLRV_ORF5 PF01690.17 OWF51000.1 - 0.024 13.4 0.1 0.038 12.7 0.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Reprolysin_3 PF13582.6 OWF51000.1 - 0.041 14.4 0.7 0.12 12.9 0.7 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Zn_peptidase_2 PF04298.12 OWF51000.1 - 0.44 9.9 0.0 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Reprolysin_4 PF13583.6 OWF51000.1 - 0.44 10.1 3.4 0.3 10.7 0.1 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF51000.1 - 0.53 10.4 2.8 0.26 11.4 0.3 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 HEM4 PF02602.15 OWF51001.1 - 7.9e-42 143.2 0.0 9.4e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Sulfotransfer_2 PF03567.14 OWF51002.1 - 4.4e-26 92.3 1.1 6.3e-22 78.7 0.1 2.1 2 0 0 2 2 2 2 Sulfotransferase family Zip PF02535.22 OWF51003.1 - 1.2 8.3 3.1 1.3 8.1 3.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter VWD PF00094.25 OWF51004.1 - 9.4e-30 104.0 0.8 2.2e-29 102.7 0.8 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain DUF3011 PF11218.8 OWF51004.1 - 1.1e-19 71.2 53.0 4e-12 46.5 25.6 4.1 2 1 2 4 4 4 3 Protein of unknown function (DUF3011) TIL PF01826.17 OWF51004.1 - 5.1e-07 29.9 9.5 5.1e-07 29.9 9.5 7.1 6 2 0 6 6 6 2 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 OWF51004.1 - 2.7e-06 27.5 5.1 2.7e-06 27.5 5.1 8.7 8 0 0 8 8 8 3 EGF domain EGF PF00008.27 OWF51004.1 - 0.004 17.4 3.5 0.004 17.4 3.5 7.0 7 1 0 7 7 7 2 EGF-like domain EGF_MSP1_1 PF12946.7 OWF51004.1 - 0.0063 16.5 6.9 0.0063 16.5 6.9 6.5 5 0 0 5 5 5 1 MSP1 EGF domain 1 cEGF PF12662.7 OWF51004.1 - 0.0087 16.0 34.7 0.17 11.9 1.4 6.1 5 0 0 5 5 5 4 Complement Clr-like EGF-like S-antigen PF05756.11 OWF51004.1 - 8.6 6.8 9.0 1 9.8 0.5 3.4 2 1 1 3 3 3 0 S-antigen protein 2OG-FeII_Oxy_3 PF13640.6 OWF51005.1 - 1.1e-20 74.4 0.1 6.2e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 OWF51005.1 - 1.1e-11 44.7 10.2 2.8e-11 43.3 10.2 1.8 1 0 0 1 1 1 1 MYND finger 2OG-FeII_Oxy_4 PF13661.6 OWF51005.1 - 5.4e-10 39.8 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TGF_beta PF00019.20 OWF51007.1 - 4.7e-24 85.3 2.1 6.3e-24 84.9 0.5 2.0 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 OWF51007.1 - 1.8e-11 44.2 0.1 3.6e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 TGF-beta propeptide MFS_1 PF07690.16 OWF51009.1 - 7.8e-37 127.0 30.0 4.8e-25 88.2 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OWF51010.1 - 3.9e-44 151.0 35.9 1.8e-25 89.7 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF51010.1 - 3.5e-07 29.4 18.3 0.00023 20.1 0.8 3.3 2 2 0 3 3 3 3 MFS_1 like family DnaJ PF00226.31 OWF51011.1 - 0.0006 19.9 0.1 0.0006 19.9 0.1 2.6 2 1 1 3 3 3 1 DnaJ domain RNase_J_C PF17770.1 OWF51011.1 - 0.067 14.2 1.4 0.067 14.2 1.4 2.8 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain Rad50_zn_hook PF04423.14 OWF51011.1 - 0.43 10.5 5.0 2.9 7.8 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif ArAE_2_N PF10337.9 OWF51011.1 - 1.2 8.1 3.8 1.7 7.6 3.8 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal YtxH PF12732.7 OWF51011.1 - 1.9 9.1 5.9 6.3 7.4 2.8 2.6 2 1 1 3 3 3 0 YtxH-like protein REV1_C PF16727.5 OWF51011.1 - 5.2 7.5 11.4 1.1e+02 3.3 9.3 3.0 2 1 0 2 2 2 0 DNA repair protein REV1 C-terminal domain AbiH PF14253.6 OWF51011.1 - 5.5 6.8 10.0 2.3 8.0 5.7 1.9 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH TPR_8 PF13181.6 OWF51011.1 - 9.5 6.7 6.4 2.6 8.5 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 OWF51012.1 - 0.0055 16.8 0.3 0.045 13.9 0.0 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.6 OWF51012.1 - 9 6.8 6.3 5.4 7.5 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 OWF51013.1 - 0.032 14.4 0.1 0.16 12.1 0.1 2.2 1 0 0 1 1 1 0 DnaJ domain Peptidase_A8 PF01252.18 OWF51013.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Signal peptidase (SPase) II Tubulin PF00091.25 OWF51015.1 - 2.1e-68 230.4 0.0 2.9e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF51015.1 - 3.7e-52 175.8 0.0 5.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OWF51015.1 - 0.00096 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 OWF51016.1 - 4.6e-68 229.3 0.0 6.1e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF51016.1 - 5e-52 175.3 0.0 7.8e-52 174.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OWF51016.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pertus-S5-tox PF09276.10 OWF51017.1 - 0.014 15.5 0.6 9.2 6.4 0.1 3.7 1 1 4 5 5 5 0 Pertussis toxin S5 subunit MotA_ExbB PF01618.16 OWF51017.1 - 0.035 13.8 7.6 41 3.9 0.0 6.1 1 1 5 6 6 6 0 MotA/TolQ/ExbB proton channel family CTXphi_pIII-N1 PF16710.5 OWF51017.1 - 0.041 14.0 1.7 0.055 13.6 0.7 1.6 1 1 1 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Tubulin PF00091.25 OWF51018.1 - 7.9e-68 228.5 0.0 1.1e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF51018.1 - 3.9e-50 169.2 0.0 6e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OWF51018.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain DUF4773 PF15998.5 OWF51019.1 - 3.1e-21 76.1 4.0 5.6e-21 75.3 4.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) Bcl-2 PF00452.19 OWF51020.1 - 6.3e-31 107.0 0.2 1e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 OWF51020.1 - 2e-06 27.4 1.5 2.6e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.6 OWF51020.1 - 0.047 14.4 0.0 0.078 13.6 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like MRJP PF03022.16 OWF51022.1 - 5.6e-43 147.4 1.9 8.4e-43 146.8 1.9 1.2 1 0 0 1 1 1 1 Major royal jelly protein Chorion_1 PF01723.16 OWF51023.1 - 0.0003 20.8 0.1 1.9 8.4 0.1 3.9 1 1 0 1 1 1 1 Chorion protein DUF4900 PF16241.5 OWF51023.1 - 0.044 14.1 3.7 16 5.9 0.3 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4900) DUF4788 PF16032.5 OWF51023.1 - 0.045 12.7 0.6 17 4.2 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4788) MRJP PF03022.16 OWF51024.1 - 4.4e-37 128.0 0.0 8.1e-37 127.1 0.0 1.4 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 OWF51024.1 - 0.0038 16.8 2.3 0.79 9.3 0.2 3.1 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Pkinase PF00069.25 OWF51025.1 - 1.2e-60 205.1 0.4 2.5e-60 204.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51025.1 - 7e-34 117.3 0.0 1.4e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fic_N PF13784.6 OWF51025.1 - 0.083 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Fic/DOC family N-terminal YabA PF06156.13 OWF51025.1 - 2.3 8.9 13.7 17 6.1 7.3 3.2 2 1 0 2 2 2 0 Initiation control protein YabA C1q PF00386.21 OWF51026.1 - 1.2e-22 80.5 0.8 1.8e-22 79.9 0.8 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF51026.1 - 0.029 14.3 0.2 0.049 13.5 0.2 1.4 1 0 0 1 1 1 0 BclA C-terminal domain SOAR PF16533.5 OWF51026.1 - 0.038 14.0 0.4 0.069 13.1 0.4 1.4 1 0 0 1 1 1 0 STIM1 Orai1-activating region Csm1_N PF18504.1 OWF51026.1 - 2.3 8.6 5.3 1.1 9.6 2.0 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain AD PF09793.9 OWF51027.1 - 8.3e-25 86.8 0.3 1.4e-24 86.1 0.0 1.5 2 0 0 2 2 2 1 Anticodon-binding domain Gemin6 PF06372.12 OWF51027.1 - 0.013 15.0 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 0 Gemin6 protein Ribosomal_L39 PF00832.20 OWF51028.1 - 0.08 12.6 0.5 18 5.1 0.0 3.6 3 2 0 3 3 3 0 Ribosomal L39 protein MMR_HSR1 PF01926.23 OWF51029.1 - 5.4e-23 81.3 0.0 9.9e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 OWF51029.1 - 1.4e-21 76.7 6.4 3.5e-21 75.4 6.4 1.6 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 OWF51029.1 - 1.8e-09 37.3 0.0 1.9e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 OWF51029.1 - 0.063 12.3 0.2 7.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OWF51029.1 - 0.17 11.9 0.4 7.8 6.5 0.0 2.8 1 1 1 2 2 2 0 Dynamin family TPP_enzyme_N PF02776.18 OWF51030.1 - 9.9e-45 152.2 0.1 2e-44 151.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OWF51030.1 - 2e-35 121.5 0.2 1.4e-34 118.8 0.1 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OWF51030.1 - 7.5e-26 90.8 1.5 2.4e-25 89.1 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3941 PF13081.6 OWF51030.1 - 0.037 14.4 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) CO_dh PF02552.16 OWF51030.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Methyltransf_31 PF13847.6 OWF51031.1 - 5.2e-26 91.3 0.0 5.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF51031.1 - 3.9e-19 69.1 0.0 5.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF51031.1 - 6.3e-19 68.4 0.0 9.1e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF51031.1 - 3.6e-16 59.7 0.0 5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF51031.1 - 1.6e-12 47.6 0.0 2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF51031.1 - 7.8e-11 41.8 0.0 9.9e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OWF51031.1 - 2.5e-08 33.5 0.1 2.9e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OWF51031.1 - 2.6e-08 33.6 0.0 3.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OWF51031.1 - 2.7e-07 30.2 0.0 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 OWF51031.1 - 9.1e-06 25.3 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 OWF51031.1 - 2.5e-05 25.3 0.1 3.4e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OWF51031.1 - 3.8e-05 23.4 0.0 5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OWF51031.1 - 5.6e-05 23.2 0.0 6.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF51031.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OWF51031.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DREV PF05219.12 OWF51031.1 - 0.033 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase GidB PF02527.15 OWF51031.1 - 0.06 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_8 PF05148.15 OWF51031.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltr_RsmB-F PF01189.17 OWF51031.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 OWF51032.1 - 1.4e-07 31.5 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF51032.1 - 2.1e-06 28.3 0.0 6.3e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF51032.1 - 2.1e-05 25.1 0.0 4e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OWF51032.1 - 2.4e-05 24.0 0.0 3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OWF51032.1 - 8.3e-05 22.5 0.0 9.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OWF51032.1 - 0.00062 19.1 0.0 0.00067 19.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 OWF51032.1 - 0.0008 20.0 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OWF51032.1 - 0.011 14.8 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.17 OWF51032.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 OWF51032.1 - 0.024 14.7 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OWF51032.1 - 0.052 12.9 0.1 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 OWF51032.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 OWF51032.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 OWF51032.1 - 0.2 11.8 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase T3SS_ATPase_C PF18269.1 OWF51033.1 - 0.02 14.8 0.0 22 5.0 0.0 4.3 2 1 4 6 6 6 0 T3SS EscN ATPase C-terminal domain Pox_E10 PF04805.12 OWF51033.1 - 0.02 14.7 18.6 0.7 9.8 4.5 3.8 1 1 3 4 4 4 0 E10-like protein conserved region Croc_4 PF17691.1 OWF51033.1 - 0.098 12.7 3.7 11 6.0 0.1 3.1 1 1 1 3 3 3 0 Contingent replication of cDNA 4 BBS2_N PF14781.6 OWF51033.1 - 4.9 7.1 8.9 27 4.7 0.2 3.4 1 1 3 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal p450 PF00067.22 OWF51034.1 - 1.7e-68 231.5 0.0 2e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-B_box PF00643.24 OWF51035.1 - 2.9e-05 24.1 4.0 6.8e-05 22.9 4.0 1.6 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 OWF51035.1 - 8.9e-05 22.6 0.7 0.0002 21.4 0.7 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DASH_Dam1 PF08653.10 OWF51035.1 - 0.16 11.8 0.7 1.2 8.9 0.5 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF4207 PF13904.6 OWF51036.1 - 4.2e-23 82.3 56.7 5.8e-23 81.9 56.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) YjbH PF06082.11 OWF51036.1 - 9.1 4.9 15.0 11 4.6 15.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Dpy-30 PF05186.13 OWF51037.1 - 2e-11 43.4 0.2 5.6e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 Dpy-30 motif Ank_5 PF13857.6 OWF51037.1 - 1.1e-09 38.3 0.1 8e-07 29.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF51037.1 - 3.2e-09 37.3 0.1 1.5e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF51037.1 - 0.00045 20.7 0.0 0.0045 17.5 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF51037.1 - 0.00058 20.1 0.0 0.027 15.0 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OWF51037.1 - 0.0064 16.9 0.0 7.7 7.1 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat THRAP3_BCLAF1 PF15440.6 OWF51037.1 - 0.18 10.8 15.8 0.24 10.4 15.8 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Borrelia_P83 PF05262.11 OWF51037.1 - 0.9 8.0 18.2 1.3 7.5 18.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 OWF51037.1 - 1.3 6.9 8.0 1.9 6.3 8.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 OWF51037.1 - 2.1 8.4 3.4 3.5 7.6 3.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dynactin_p62 PF05502.13 OWF51037.1 - 2.5 6.8 9.3 3.6 6.2 9.3 1.2 1 0 0 1 1 1 0 Dynactin p62 family Presenilin PF01080.17 OWF51037.1 - 6.4 5.4 11.8 9.1 4.9 11.8 1.2 1 0 0 1 1 1 0 Presenilin MAT1 PF06391.13 OWF51037.1 - 9.5 6.0 25.3 5.1 6.9 18.5 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF16 PF01519.16 OWF51038.1 - 8.4e-17 61.6 26.7 1.5e-05 25.4 2.9 4.8 1 1 3 4 4 4 4 Protein of unknown function DUF16 Herpes_BLLF1 PF05109.13 OWF51038.1 - 2.8e-13 48.8 85.4 3.8e-07 28.5 27.0 2.5 1 1 2 3 3 3 3 Herpes virus major outer envelope glycoprotein (BLLF1) DASH_Duo1 PF08651.10 OWF51038.1 - 9.4e-13 47.7 51.7 0.00094 18.9 1.9 7.4 1 1 6 7 7 7 6 DASH complex subunit Duo1 DUF3540 PF12059.8 OWF51038.1 - 1.3e-11 44.8 15.4 0.0047 16.8 0.2 4.4 1 1 3 4 4 4 4 Protein of unknown function (DUF3540) WXG100 PF06013.12 OWF51038.1 - 3.4e-11 43.2 22.3 0.02 15.1 2.0 7.3 1 1 4 5 5 5 5 Proteins of 100 residues with WXG DUF3552 PF12072.8 OWF51038.1 - 4.4e-11 42.6 34.0 0.025 14.0 1.7 6.3 1 1 4 5 5 5 4 Domain of unknown function (DUF3552) DUF948 PF06103.11 OWF51038.1 - 1.4e-10 41.3 52.8 0.0074 16.5 9.0 5.8 1 1 4 5 5 5 3 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OWF51038.1 - 3e-10 40.2 39.9 0.023 14.8 4.2 5.1 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) MCPsignal PF00015.21 OWF51038.1 - 1.9e-09 37.6 49.0 0.023 14.5 7.7 4.9 1 1 5 6 6 6 6 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE_C PF12352.8 OWF51038.1 - 3.1e-08 33.8 35.5 0.32 11.3 0.9 8.2 1 1 8 9 9 8 5 Snare region anchored in the vesicle membrane C-terminus Spc7 PF08317.11 OWF51038.1 - 4.5e-08 32.3 38.2 0.00041 19.3 9.4 3.1 1 1 2 3 3 3 3 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 OWF51038.1 - 9.9e-08 32.3 21.7 0.0068 16.8 2.5 5.3 1 1 6 7 7 7 5 Snapin/Pallidin HrpB7 PF09486.10 OWF51038.1 - 2.2e-07 31.4 0.9 0.016 15.6 0.0 4.2 1 1 3 4 4 4 3 Bacterial type III secretion protein (HrpB7) Arfaptin PF06456.13 OWF51038.1 - 2.2e-07 30.7 24.4 0.0043 16.7 8.4 3.3 1 1 2 3 3 3 3 Arfaptin-like domain Exonuc_VII_L PF02601.15 OWF51038.1 - 7.4e-07 29.0 28.1 0.076 12.6 8.3 3.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit KxDL PF10241.9 OWF51038.1 - 8.5e-07 29.2 30.9 0.54 10.6 2.8 6.2 1 1 4 5 5 5 2 Uncharacterized conserved protein IFT57 PF10498.9 OWF51038.1 - 7e-06 25.3 40.6 0.01 14.8 7.9 4.2 1 1 5 6 6 6 6 Intra-flagellar transport protein 57 TMP_2 PF06791.13 OWF51038.1 - 1.2e-05 25.1 32.6 0.042 13.5 8.7 4.6 1 1 4 5 5 5 4 Prophage tail length tape measure protein DUF745 PF05335.13 OWF51038.1 - 1.6e-05 24.7 16.3 0.046 13.4 2.4 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF745) DUF4200 PF13863.6 OWF51038.1 - 2e-05 25.0 4.1 0.23 11.9 0.1 3.6 1 1 1 3 3 3 2 Domain of unknown function (DUF4200) Laminin_II PF06009.12 OWF51038.1 - 2.4e-05 24.4 45.0 0.49 10.4 6.2 5.3 1 1 5 6 6 6 5 Laminin Domain II APG17 PF04108.12 OWF51038.1 - 2.8e-05 23.4 38.8 0.015 14.4 7.1 3.5 1 1 2 3 3 3 3 Autophagy protein Apg17 YtxH PF12732.7 OWF51038.1 - 6.6e-05 23.4 31.5 1.8e+04 -16.5 31.5 6.3 1 1 0 1 1 0 0 YtxH-like protein Mce4_CUP1 PF11887.8 OWF51038.1 - 8e-05 22.2 46.2 0.013 14.9 13.5 3.4 1 1 2 3 3 3 2 Cholesterol uptake porter CUP1 of Mce4, putative PI3K_P85_iSH2 PF16454.5 OWF51038.1 - 0.00012 21.7 22.3 1.2 8.7 0.7 5.7 1 1 2 3 3 3 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RPW8 PF05659.11 OWF51038.1 - 0.0003 20.5 29.4 0.048 13.3 1.4 5.2 1 1 3 5 5 5 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Collagen_mid PF15984.5 OWF51038.1 - 0.00048 19.9 23.9 0.53 10.0 1.7 4.6 1 1 2 3 3 3 1 Bacterial collagen, middle region HMMR_N PF15905.5 OWF51038.1 - 0.0007 19.2 39.2 0.029 13.8 8.9 3.1 1 1 2 3 3 3 3 Hyaluronan mediated motility receptor N-terminal UPF0449 PF15136.6 OWF51038.1 - 0.00074 19.9 33.0 1.9 9.0 2.4 5.6 1 1 3 4 4 4 1 Uncharacterised protein family UPF0449 BLOC1_2 PF10046.9 OWF51038.1 - 0.0015 18.8 37.1 0.47 10.8 8.5 5.6 1 1 3 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.20 OWF51038.1 - 0.0019 17.6 39.7 0.26 10.6 6.0 4.4 1 1 4 5 5 5 3 Tropomyosin EzrA PF06160.12 OWF51038.1 - 0.002 16.4 33.2 0.016 13.4 33.2 2.2 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA YkyA PF10368.9 OWF51038.1 - 0.002 17.8 37.5 1.7 8.3 7.4 4.0 1 1 2 3 3 3 1 Putative cell-wall binding lipoprotein YjcZ PF13990.6 OWF51038.1 - 0.0021 17.5 15.3 0.56 9.5 1.1 3.4 1 1 1 3 3 3 3 YjcZ-like protein FH2 PF02181.23 OWF51038.1 - 0.0027 16.9 21.1 0.16 11.1 1.2 3.7 1 1 4 5 5 5 5 Formin Homology 2 Domain DUF3450 PF11932.8 OWF51038.1 - 0.003 16.9 31.2 0.16 11.3 7.2 3.2 1 1 1 3 3 3 3 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 OWF51038.1 - 0.0038 17.3 21.5 17 5.6 0.3 7.1 1 1 7 8 8 8 0 bZIP transcription factor Filament PF00038.21 OWF51038.1 - 0.0049 16.5 35.0 0.34 10.5 4.3 3.9 1 1 2 3 3 3 2 Intermediate filament protein Sipho_Gp157 PF05565.11 OWF51038.1 - 0.005 16.9 13.6 0.21 11.6 0.6 4.0 1 1 3 4 4 4 1 Siphovirus Gp157 DHR10 PF18595.1 OWF51038.1 - 0.0076 16.3 30.4 2 8.5 8.9 4.5 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain DUF3584 PF12128.8 OWF51038.1 - 0.0086 13.7 37.7 0.014 12.9 36.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) HemX PF04375.14 OWF51038.1 - 0.01 15.2 35.5 0.74 9.0 3.8 4.1 1 1 3 4 4 4 0 HemX, putative uroporphyrinogen-III C-methyltransferase BAR PF03114.18 OWF51038.1 - 0.011 15.4 23.1 0.35 10.5 9.7 3.3 1 1 2 3 3 3 0 BAR domain DUF148 PF02520.17 OWF51038.1 - 0.012 15.7 41.8 1 9.5 3.7 5.1 1 1 3 5 5 5 0 Domain of unknown function DUF148 APG6_N PF17675.1 OWF51038.1 - 0.014 15.9 40.4 1.7 9.2 7.4 3.9 1 1 1 2 2 1 0 Apg6 coiled-coil region COG2 PF06148.11 OWF51038.1 - 0.019 15.1 20.9 2.7 8.1 3.3 4.7 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Pro_Al_protease PF02983.14 OWF51038.1 - 0.046 13.8 30.4 37 4.5 0.8 10.8 1 1 7 8 8 7 0 Alpha-lytic protease prodomain UPF0242 PF06785.11 OWF51038.1 - 0.049 13.7 36.4 1.7 8.7 11.1 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus mTERF PF02536.14 OWF51038.1 - 0.07 12.1 0.0 11 4.8 0.0 2.7 1 1 0 2 2 2 0 mTERF Atg14 PF10186.9 OWF51038.1 - 0.075 12.1 32.9 2.5 7.1 13.3 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ING PF12998.7 OWF51038.1 - 0.085 13.5 15.9 9.3 6.9 1.4 4.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Prefoldin_2 PF01920.20 OWF51038.1 - 0.099 12.6 39.9 10 6.1 1.0 7.4 1 1 6 8 8 8 0 Prefoldin subunit RasGAP_C PF03836.15 OWF51038.1 - 0.13 12.4 33.4 15 5.7 1.1 5.4 1 1 2 3 3 2 0 RasGAP C-terminus WEMBL PF05701.11 OWF51038.1 - 0.14 10.9 30.7 0.3 9.7 8.0 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF2959 PF11172.8 OWF51038.1 - 0.14 12.3 22.6 1.6 8.8 5.0 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) TMPIT PF07851.13 OWF51038.1 - 0.22 10.7 31.7 1.8 7.7 6.9 3.6 1 1 1 2 2 1 0 TMPIT-like protein Nre_C PF04895.12 OWF51038.1 - 0.47 10.4 19.9 56 3.7 2.4 5.8 1 1 4 5 5 5 0 Archaeal Nre, C-terminal FliT PF05400.13 OWF51038.1 - 0.58 11.0 10.5 59 4.6 2.3 4.8 1 1 2 3 3 3 0 Flagellar protein FliT Prefoldin PF02996.17 OWF51038.1 - 0.77 9.7 37.7 5.7 6.9 2.0 7.0 1 1 5 6 6 6 0 Prefoldin subunit ArAE_2_N PF10337.9 OWF51038.1 - 0.96 8.4 21.2 8.5 5.3 6.8 2.8 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal Fib_alpha PF08702.10 OWF51038.1 - 0.99 9.6 44.1 1.4e+02 2.7 10.1 4.2 1 1 2 3 3 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 OWF51038.1 - 1 9.5 59.9 60 3.8 8.9 4.4 1 1 1 2 2 1 0 Tropomyosin like Aida_N PF08910.10 OWF51038.1 - 1.6 9.2 19.0 5.4 7.5 0.8 4.9 1 1 4 5 5 5 0 Aida N-terminus DUF1759 PF03564.15 OWF51038.1 - 1.8 8.5 19.5 11 5.9 0.9 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1759) TMF_TATA_bd PF12325.8 OWF51038.1 - 2 8.7 35.5 1.6 9.0 7.9 4.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CheZ PF04344.13 OWF51038.1 - 2.1 8.3 36.5 8.2 6.3 10.4 3.9 1 1 4 5 5 5 0 Chemotaxis phosphatase, CheZ NPV_P10 PF05531.12 OWF51038.1 - 2.4 8.7 52.1 1.8e+04 -37.5 52.1 7.4 1 1 0 1 1 0 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 OWF51038.1 - 3 8.1 18.5 14 5.9 1.6 4.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.21 OWF51038.1 - 3.8 8.1 18.0 1.8 9.1 2.5 3.7 1 1 2 3 3 3 0 Spectrin repeat MAD PF05557.13 OWF51038.1 - 4.6 5.5 34.1 4 5.7 14.3 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Synaptobrevin PF00957.21 OWF51038.1 - 5.3 6.9 47.7 25 4.8 0.5 7.9 1 1 6 7 7 7 0 Synaptobrevin BAG6 PF12057.8 OWF51038.1 - 6.2 6.5 24.7 6.4 6.5 0.5 6.2 1 1 6 7 7 7 0 BCL2-associated athanogene 6 MCC-bdg_PDZ PF10506.9 OWF51038.1 - 6.5 6.9 19.8 5.9 7.0 0.5 6.8 1 1 7 10 10 10 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TPR_MLP1_2 PF07926.12 OWF51038.1 - 7.7 6.6 38.3 19 5.3 10.8 4.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 OWF51038.1 - 8.8 6.3 38.5 9.4 6.3 14.5 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OWF51038.1 - 9.1 6.7 37.2 15 6.0 12.5 3.2 1 1 1 2 2 1 0 Fez1 RmuC PF02646.16 OWF51038.1 - 9.8 5.2 38.0 5.5 6.0 3.1 5.5 1 1 3 4 4 3 0 RmuC family Ank_2 PF12796.7 OWF51039.1 - 1.7e-21 76.5 0.3 1.2e-14 54.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF51039.1 - 5.7e-21 74.6 1.9 3e-14 53.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF51039.1 - 1e-18 66.9 0.2 5.2e-07 29.8 0.1 4.3 4 0 0 4 4 3 3 Ankyrin repeat Ank_5 PF13857.6 OWF51039.1 - 4.6e-18 65.0 2.2 1.4e-08 34.8 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Pkinase PF00069.25 OWF51039.1 - 1.2e-12 47.8 0.6 1.9e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_3 PF13606.6 OWF51039.1 - 3.2e-11 42.4 0.2 0.0013 19.1 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Pkinase_Tyr PF07714.17 OWF51039.1 - 6.2e-09 35.5 0.2 1.4e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Golgin_A5 PF09787.9 OWF51039.1 - 0.012 15.1 3.0 0.02 14.4 3.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Kinase-like PF14531.6 OWF51039.1 - 0.036 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF745 PF05335.13 OWF51039.1 - 0.038 13.7 0.2 0.068 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) YabA PF06156.13 OWF51039.1 - 0.3 11.7 3.8 0.8 10.4 3.8 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DUF4709 PF15821.5 OWF51040.1 - 1.2e-42 144.7 4.4 1.2e-42 144.7 4.4 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4709) ArAE_2 PF10334.9 OWF51040.1 - 0.00026 20.9 0.6 0.0014 18.5 0.6 2.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 DUF3450 PF11932.8 OWF51040.1 - 0.032 13.6 0.4 0.032 13.6 0.4 5.0 3 2 2 5 5 5 0 Protein of unknown function (DUF3450) DUF4988 PF16378.5 OWF51040.1 - 0.21 11.2 9.9 0.085 12.5 2.3 2.8 3 0 0 3 3 3 0 Domain of unknown function BCL_N PF04714.13 OWF51040.1 - 2.2 8.4 8.6 0.41 10.7 0.3 3.5 3 0 0 3 3 3 0 BCL7, N-terminal conserver region AAA_13 PF13166.6 OWF51040.1 - 8.8 4.8 52.3 0.0073 15.0 9.7 3.1 2 1 2 4 4 4 0 AAA domain LCM PF04072.14 OWF51041.1 - 1.6e-31 109.7 0.0 7e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 OWF51041.1 - 1.4e-18 66.6 16.1 1e-05 25.4 0.1 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF51041.1 - 4.1e-14 52.2 9.3 4.9e-06 26.4 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 OWF51041.1 - 1.4e-11 44.2 13.3 0.01 16.1 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OWF51041.1 - 1.3e-10 40.7 4.0 0.043 13.4 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OWF51041.1 - 5e-07 29.4 16.9 0.065 13.2 0.1 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 OWF51041.1 - 0.0063 16.8 4.3 2.7 8.4 0.0 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF4205 PF13898.6 OWF51042.1 - 2.1e-62 211.1 0.1 6.6e-56 189.7 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) EF-hand_1 PF00036.32 OWF51042.1 - 0.0011 18.4 0.0 0.0058 16.1 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OWF51042.1 - 0.0048 16.7 0.0 0.014 15.3 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain DUF3583 PF12126.8 OWF51042.1 - 0.025 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Mucin PF01456.17 OWF51043.1 - 0.6 10.1 21.7 0.032 14.2 15.8 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein F-box-like PF12937.7 OWF51044.1 - 5.8e-09 35.7 0.2 5.8e-09 35.7 0.2 2.6 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.6 OWF51044.1 - 0.00021 21.1 3.6 5.6 7.3 0.0 7.4 9 0 0 9 9 9 1 Leucine Rich repeat F-box PF00646.33 OWF51044.1 - 0.00023 20.9 1.1 0.001 18.9 0.2 2.7 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 OWF51044.1 - 0.1 12.4 4.2 10 6.0 0.3 4.5 4 0 0 4 4 4 0 Leucine rich repeat Rod_C PF10493.9 OWF51044.1 - 0.12 10.8 1.0 0.87 7.9 0.0 2.3 2 0 0 2 2 2 0 Rough deal protein C-terminal region zf-HC5HC2H_2 PF13832.6 OWF51045.1 - 4.6e-28 97.6 14.5 4.6e-28 97.6 14.5 2.7 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OWF51045.1 - 1.5e-19 70.0 12.2 1.5e-19 70.0 12.2 3.4 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OWF51045.1 - 2.9e-13 49.1 3.8 2.9e-13 49.1 3.8 3.3 2 1 1 3 3 3 1 PHD-finger PHD PF00628.29 OWF51045.1 - 1.9e-08 34.0 9.3 1.9e-08 34.0 9.3 3.5 3 1 0 3 3 3 1 PHD-finger FANCL_C PF11793.8 OWF51045.1 - 4 7.7 19.1 2.6 8.3 2.3 3.1 2 0 0 2 2 2 0 FANCL C-terminal domain Glycos_transf_2 PF00535.26 OWF51046.1 - 8.8e-36 123.3 0.0 2e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF51046.1 - 1.4e-28 99.7 2.5 2.5e-28 98.9 2.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 OWF51046.1 - 2.1e-07 31.1 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF51046.1 - 2.4e-06 27.1 0.1 5.9e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF51046.1 - 0.00022 20.8 0.0 0.00048 19.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 OWF51046.1 - 0.00029 21.5 0.6 1.1 10.0 0.4 2.8 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Glyco_trans_2_3 PF13632.6 OWF51046.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_10 PF00852.19 OWF51049.1 - 2.2e-47 161.0 1.7 3.7e-47 160.3 1.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF51049.1 - 1.1e-16 61.2 0.2 2.6e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DUF2787 PF10980.8 OWF51049.1 - 0.0041 17.3 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2787) UCR_14kD PF02271.16 OWF51049.1 - 0.084 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DER1 PF04511.15 OWF51050.1 - 2e-66 223.6 14.7 2.3e-66 223.4 14.7 1.0 1 0 0 1 1 1 1 Der1-like family RabGAP-TBC PF00566.18 OWF51051.1 - 3.3e-14 53.1 2.2 3.3e-14 53.1 2.2 2.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 OWF51051.1 - 1.2e-06 29.1 1.6 8.5 7.4 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 OWF51051.1 - 0.00023 20.6 0.1 0.0055 16.1 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain Neisseria_PilC PF05567.11 OWF51051.1 - 0.21 10.6 0.0 0.35 9.8 0.0 1.4 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain 7tm_1 PF00001.21 OWF51052.1 - 2.1e-45 155.1 14.2 3.3e-45 154.5 14.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FAM92 PF06730.11 OWF51053.1 - 8.4e-55 185.6 8.1 1.1e-54 185.2 8.1 1.1 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.18 OWF51053.1 - 8.1e-08 32.2 7.6 1.4e-07 31.4 7.6 1.4 1 0 0 1 1 1 1 BAR domain Vps5 PF09325.10 OWF51053.1 - 8.3e-06 25.5 8.3 9.8e-05 22.0 8.3 2.1 1 1 0 1 1 1 1 Vps5 C terminal like BAR_3 PF16746.5 OWF51053.1 - 3.7e-05 23.5 10.4 5.3e-05 23.0 10.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 OWF51053.1 - 0.061 12.8 3.4 0.094 12.2 3.4 1.5 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein TPR_MLP1_2 PF07926.12 OWF51053.1 - 0.48 10.5 7.6 0.046 13.8 1.9 2.1 2 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 OWF51053.1 - 0.84 9.2 7.3 4.4 6.8 0.4 2.5 2 1 0 2 2 2 0 fzo-like conserved region TEX13 PF15186.6 OWF51053.1 - 7.3 6.3 8.7 3.9 7.1 0.1 3.1 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family DUF3472 PF11958.8 OWF51054.1 - 2.1e-38 132.5 0.5 2.7e-38 132.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 OWF51054.1 - 5.1e-07 29.8 0.0 9.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) Ldl_recept_a PF00057.18 OWF51055.1 - 0.0018 18.5 6.2 0.0018 18.5 6.2 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Comm PF15957.5 OWF51055.1 - 0.005 17.2 1.2 0.053 13.9 1.2 2.4 1 1 0 1 1 1 1 Commissureless HemY_N PF07219.13 OWF51055.1 - 0.044 14.0 0.5 0.083 13.1 0.5 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Prominin PF05478.11 OWF51055.1 - 0.045 11.7 0.0 0.061 11.3 0.0 1.1 1 0 0 1 1 1 0 Prominin CUB PF00431.20 OWF51055.1 - 0.047 14.0 0.2 0.3 11.5 0.1 2.1 2 0 0 2 2 2 0 CUB domain Isochorismatase PF00857.20 OWF51056.1 - 1.7e-31 109.7 0.0 4.4e-31 108.4 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family EF-hand_7 PF13499.6 OWF51056.1 - 2.6e-08 34.2 1.3 9.2e-08 32.4 1.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF51056.1 - 4.2e-08 32.2 7.7 0.00031 20.1 1.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OWF51056.1 - 6.1e-07 29.2 5.0 0.012 15.5 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF51056.1 - 8.3e-06 25.3 7.4 0.015 15.1 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OWF51056.1 - 2.7e-05 23.4 2.8 0.0048 16.3 0.8 2.8 2 0 0 2 2 2 2 EF hand IspD PF01128.19 OWF51056.1 - 0.016 15.0 0.2 0.025 14.3 0.2 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SPARC_Ca_bdg PF10591.9 OWF51056.1 - 0.025 14.9 0.5 0.18 12.1 0.3 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF51056.1 - 0.12 12.3 1.1 0.79 9.7 0.1 2.5 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand ELK PF03789.13 OWF51057.1 - 1.8e-05 24.7 3.6 12 6.2 0.0 5.8 6 0 0 6 6 5 1 ELK domain DUF4939 PF16297.5 OWF51057.1 - 0.001 19.0 5.7 1.2 9.0 0.1 3.8 1 1 0 3 3 3 1 Domain of unknown function (DUF4939) CCDC53 PF10152.9 OWF51057.1 - 0.0014 19.1 4.1 17 5.8 0.1 4.9 1 1 4 6 6 6 0 Subunit CCDC53 of WASH complex HTH_16 PF12645.7 OWF51057.1 - 0.0017 18.4 25.0 5.2 7.2 0.1 8.2 1 1 9 11 11 11 4 Helix-turn-helix domain CspB_prodomain PF18425.1 OWF51057.1 - 0.0091 16.0 3.5 7.5 6.6 0.1 4.1 1 1 3 5 5 5 1 Csp protease B prodomain GlnE PF03710.15 OWF51057.1 - 0.051 13.0 4.2 0.24 10.8 0.9 2.6 1 1 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase ACP_PD PF04336.12 OWF51057.1 - 0.15 12.5 22.1 2.2 8.8 6.5 3.9 1 1 3 4 4 4 0 Acyl carrier protein phosphodiesterase Importin_rep_4 PF18808.1 OWF51057.1 - 0.2 11.9 2.4 28 5.1 0.1 3.5 1 1 3 4 4 4 0 Importin repeat MetOD1 PF18546.1 OWF51057.1 - 0.22 11.5 2.2 48 3.9 0.0 3.6 1 1 2 4 4 4 0 Metanogen output domain 1 BRE PF06113.12 OWF51057.1 - 0.3 9.9 5.8 1.8 7.3 0.8 2.7 1 1 2 3 3 3 0 Brain and reproductive organ-expressed protein (BRE) DUF1043 PF06295.12 OWF51057.1 - 0.58 10.2 33.4 3.7 7.6 5.4 4.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) CLASP_N PF12348.8 OWF51057.1 - 1.8 8.1 20.4 3.2 7.2 4.5 2.1 1 1 1 2 2 2 0 CLASP N terminal nlz1 PF12402.8 OWF51057.1 - 4 7.9 16.7 91 3.6 0.3 7.0 2 2 6 9 9 9 0 NocA-like zinc-finger protein 1 SDH_sah PF01972.16 OWF51057.1 - 8.9 5.2 12.8 4.8 6.1 0.7 3.6 1 1 2 4 4 4 0 Serine dehydrogenase proteinase HTH_16 PF12645.7 OWF51058.1 - 0.0014 18.6 18.8 7.5 6.7 0.6 6.9 1 1 6 7 7 7 2 Helix-turn-helix domain DUF4939 PF16297.5 OWF51058.1 - 0.0029 17.5 5.7 0.34 10.8 0.1 3.4 1 1 2 3 3 3 2 Domain of unknown function (DUF4939) ELK PF03789.13 OWF51058.1 - 0.0094 16.0 1.5 21 5.3 0.0 4.4 5 0 0 5 5 5 0 ELK domain CCDC53 PF10152.9 OWF51058.1 - 0.02 15.3 5.3 15 6.0 0.2 4.4 1 1 4 5 5 5 0 Subunit CCDC53 of WASH complex MetOD1 PF18546.1 OWF51058.1 - 0.054 13.5 1.9 0.89 9.5 0.2 2.9 1 1 2 3 3 3 0 Metanogen output domain 1 Ribosomal_S18 PF01084.20 OWF51058.1 - 0.18 12.1 4.7 5.5 7.3 0.1 4.0 2 1 2 4 4 4 0 Ribosomal protein S18 CspB_prodomain PF18425.1 OWF51058.1 - 0.26 11.3 3.0 25 4.9 0.2 3.2 1 1 3 4 4 4 0 Csp protease B prodomain ISG65-75 PF11727.8 OWF51058.1 - 0.32 10.2 1.5 2.6 7.2 0.1 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein nlz1 PF12402.8 OWF51058.1 - 1.8 9.1 6.7 76 3.8 0.1 4.8 3 1 3 6 6 6 0 NocA-like zinc-finger protein 1 DUF1043 PF06295.12 OWF51058.1 - 1.8 8.6 23.0 5.8 6.9 5.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) HAUS2 PF15003.6 OWF51058.1 - 7.3 6.3 10.6 1.7 8.3 0.4 2.6 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 2 CLASP_N PF12348.8 OWF51058.1 - 7.3 6.1 13.2 1.3 8.5 5.5 2.0 1 1 1 2 2 2 0 CLASP N terminal ATP-gua_Ptrans PF00217.19 OWF51059.1 - 4.1e-71 238.8 0.0 5.2e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 OWF51059.1 - 6.7e-19 68.1 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF4390 PF14334.6 OWF51059.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) zf-RING_UBOX PF13445.6 OWF51060.1 - 1.7e-09 37.5 5.7 1.7e-09 37.5 5.7 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF51060.1 - 1.7e-08 34.2 3.6 1.7e-08 34.2 3.6 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51060.1 - 3.3e-07 30.4 5.2 3.3e-07 30.4 5.2 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF51060.1 - 1.2e-06 28.3 2.8 1.2e-06 28.3 2.8 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51060.1 - 1.7e-06 28.3 4.3 1.7e-06 28.3 4.3 2.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF51060.1 - 2.4e-06 27.3 2.9 2.4e-06 27.3 2.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF51060.1 - 7.1e-06 25.9 4.3 7.1e-06 25.9 4.3 2.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-B_box PF00643.24 OWF51060.1 - 0.00042 20.4 12.7 0.00042 20.4 12.7 2.6 3 0 0 3 3 2 1 B-box zinc finger Prok-RING_4 PF14447.6 OWF51060.1 - 0.00045 20.0 2.3 0.00045 20.0 2.3 2.7 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 Apolipoprotein PF01442.18 OWF51060.1 - 0.029 14.3 1.9 0.065 13.1 1.9 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-RING_10 PF16685.5 OWF51060.1 - 1.1 9.5 16.3 2 8.6 1.3 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Laminin_II PF06009.12 OWF51060.1 - 1.2 9.2 8.4 15 5.6 6.4 2.5 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.11 OWF51060.1 - 5.4 5.8 7.3 8.1 5.2 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MIEAP PF16026.5 OWF51061.1 - 1.1e-51 175.9 1.5 1.9e-51 175.1 0.0 1.9 2 0 0 2 2 2 1 Mitochondria-eating protein Spc7 PF08317.11 OWF51061.1 - 0.0099 14.8 6.1 0.018 13.9 6.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein LURAP PF14854.6 OWF51061.1 - 0.012 15.5 1.9 0.034 14.1 1.9 1.7 1 0 0 1 1 1 0 Leucine rich adaptor protein HMMR_N PF15905.5 OWF51061.1 - 0.015 14.8 3.9 0.034 13.6 3.9 1.7 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 OWF51061.1 - 0.015 15.4 5.8 0.051 13.6 4.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 OWF51061.1 - 0.016 14.7 7.3 0.026 14.0 7.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 KxDL PF10241.9 OWF51061.1 - 0.017 15.4 3.1 0.029 14.7 1.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein IceA2 PF05862.11 OWF51061.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Fez1 PF06818.15 OWF51061.1 - 0.047 14.2 5.9 0.091 13.2 5.9 1.4 1 0 0 1 1 1 0 Fez1 DUF641 PF04859.12 OWF51061.1 - 0.059 13.7 6.2 0.34 11.2 1.1 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) OmpH PF03938.14 OWF51061.1 - 0.062 13.6 4.5 0.12 12.7 4.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPD52 PF04201.15 OWF51061.1 - 0.065 12.8 0.3 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 Tumour protein D52 family Filament PF00038.21 OWF51061.1 - 0.087 12.4 9.5 0.35 10.4 9.5 1.8 1 1 0 1 1 1 0 Intermediate filament protein Lzipper-MIP1 PF14389.6 OWF51061.1 - 0.18 12.1 2.1 0.51 10.7 1.8 2.0 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4200 PF13863.6 OWF51061.1 - 0.19 12.1 6.8 0.59 10.5 6.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Macoilin PF09726.9 OWF51061.1 - 0.2 10.2 3.7 0.34 9.4 3.7 1.4 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 OWF51061.1 - 0.26 10.6 3.7 0.41 9.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 OWF51061.1 - 0.38 10.9 9.8 1 9.5 2.7 2.4 1 1 1 2 2 2 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 OWF51061.1 - 0.38 11.0 8.6 0.77 10.0 8.6 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 OWF51061.1 - 0.46 10.5 2.2 0.92 9.6 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 OWF51061.1 - 0.47 9.8 7.7 1.1 8.6 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 OWF51061.1 - 0.67 10.1 4.6 1.8 8.8 4.6 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 OWF51061.1 - 5 7.4 8.1 80 3.6 8.1 2.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Cep57_CLD_2 PF14197.6 OWF51061.1 - 8.1 6.6 12.2 1.7 8.8 1.0 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Nup96 PF12110.8 OWF51062.1 - 2.4e-86 289.5 5.5 3.5e-86 288.9 5.5 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OWF51062.1 - 8.7e-44 149.2 0.0 1.9e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OWF51062.1 - 0.0042 17.9 39.0 0.0042 17.9 39.0 8.9 4 2 3 7 7 7 3 Nucleoporin FG repeat region SH3_2 PF07653.17 OWF51063.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4226 PF10774.9 OWF51063.1 - 0.0092 16.2 2.8 0.02 15.1 2.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4226) SH3_1 PF00018.28 OWF51063.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.9 1 1 0 1 1 1 0 SH3 domain Sec8_exocyst PF04048.14 OWF51063.1 - 0.23 11.3 5.9 0.35 10.8 0.1 2.6 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Cadherin PF00028.17 OWF51064.1 - 0 1811.1 136.0 7.2e-24 84.1 2.1 35.4 35 0 0 35 35 35 34 Cadherin domain Laminin_G_2 PF02210.24 OWF51064.1 - 6e-36 123.8 5.4 5.8e-18 65.7 0.1 3.8 3 0 0 3 3 2 2 Laminin G domain Laminin_G_1 PF00054.23 OWF51064.1 - 1.9e-33 115.4 0.5 9.8e-16 58.2 0.0 3.7 3 0 0 3 3 3 2 Laminin G domain Cadherin_2 PF08266.12 OWF51064.1 - 2.6e-32 110.5 0.1 0.28 11.0 0.0 23.3 28 1 0 28 28 28 4 Cadherin-like Cadherin_pro PF08758.11 OWF51064.1 - 2.2e-18 66.2 4.0 0.028 14.6 0.1 12.8 15 0 0 15 15 13 3 Cadherin prodomain like RET_CLD1 PF17756.1 OWF51064.1 - 1.4e-14 54.5 0.6 0.94 9.8 0.0 13.7 17 0 0 17 17 15 2 RET Cadherin like domain 1 Cadherin_3 PF16184.5 OWF51064.1 - 5e-14 52.2 84.5 0.075 13.0 0.0 24.1 26 1 1 27 27 27 6 Cadherin-like EGF PF00008.27 OWF51064.1 - 4e-13 49.4 74.3 1.3e-07 31.7 10.3 6.4 6 0 0 6 6 6 4 EGF-like domain hEGF PF12661.7 OWF51064.1 - 2.1e-07 31.3 61.1 0.0012 19.4 6.5 6.2 6 0 0 6 6 5 4 Human growth factor-like EGF Laminin_G_3 PF13385.6 OWF51064.1 - 1.3e-06 28.6 7.2 0.00048 20.3 1.0 4.3 3 0 0 3 3 2 2 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 OWF51064.1 - 1.7e-05 25.1 90.9 0.01 16.2 12.0 6.5 6 1 0 6 6 5 4 EGF-like domain EGF_CA PF07645.15 OWF51064.1 - 0.0012 19.0 7.2 0.0012 19.0 7.2 5.8 4 2 2 6 6 6 1 Calcium-binding EGF domain EphA2_TM PF14575.6 OWF51064.1 - 0.014 16.3 0.0 0.032 15.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4879 PF16219.5 OWF51064.1 - 0.023 14.9 0.6 0.16 12.2 0.1 2.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4879) ChitinaseA_N PF08329.10 OWF51064.1 - 0.15 11.7 1.4 15 5.3 0.0 3.9 3 0 0 3 3 3 0 Chitinase A, N-terminal domain DUF347 PF03988.12 OWF51064.1 - 0.39 11.0 2.0 0.72 10.1 0.2 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Senescence PF06911.12 OWF51065.1 - 4.8e-39 134.6 6.7 4.8e-39 134.6 6.7 2.3 3 0 0 3 3 3 1 Senescence-associated protein MIT PF04212.18 OWF51065.1 - 5.2e-05 23.2 2.1 0.00012 22.0 2.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Intron_maturas2 PF01348.21 OWF51065.1 - 0.086 12.8 0.1 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Type II intron maturase Aida_N PF08910.10 OWF51065.1 - 0.1 13.0 3.1 0.14 12.6 1.3 2.1 2 0 0 2 2 2 0 Aida N-terminus TPR_1 PF00515.28 OWF51065.1 - 0.57 10.1 1.5 2.1 8.3 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Solute_trans_a PF03619.16 OWF51066.1 - 7.1e-97 324.1 14.3 9.6e-97 323.6 14.3 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MAJIN PF15077.6 OWF51066.1 - 5.8 6.6 6.3 11 5.7 6.3 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Gti1_Pac2 PF09729.9 OWF51068.1 - 2.4 8.2 15.3 0.018 15.2 5.4 2.3 2 1 0 2 2 2 0 Gti1/Pac2 family Denso_VP4 PF02336.15 OWF51069.1 - 0.39 9.6 17.8 12 4.6 0.0 6.9 2 2 7 9 9 9 0 Capsid protein VP4 TTc_toxin_rep PF18807.1 OWF51069.1 - 1.3 8.9 15.5 1.4e+02 2.4 0.0 9.2 13 0 0 13 13 13 0 Tripartite Tc toxins repeat Lig_chan-Glu_bd PF10613.9 OWF51070.1 - 2.1e-24 86.0 0.0 3.4e-22 78.8 0.0 2.6 2 0 0 2 2 2 2 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF51070.1 - 8.7e-24 84.2 0.0 2.1e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 OWF51070.1 - 3e-23 82.3 0.0 5.6e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 OWF51070.1 - 9.2e-15 54.6 0.0 2.7e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 Receptor family ligand binding region TMC PF07810.13 OWF51071.1 - 1e-35 122.7 1.0 1e-35 122.7 1.0 3.4 4 0 0 4 4 4 1 TMC domain Shisa PF13908.6 OWF51071.1 - 0.013 15.7 0.5 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator CBM_35 PF16990.5 OWF51071.1 - 0.028 14.7 0.4 0.24 11.7 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) SSF PF00474.17 OWF51072.1 - 2.2e-08 33.4 9.3 2.8e-08 33.1 9.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DHHC PF01529.20 OWF51072.1 - 5 7.2 6.8 1.4 9.0 0.3 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase SSF PF00474.17 OWF51073.1 - 1.8e-06 27.1 1.7 2.2e-06 26.8 1.7 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Tetraspanin PF00335.20 OWF51073.1 - 0.096 12.4 0.6 0.14 11.8 0.6 1.3 1 1 0 1 1 1 0 Tetraspanin family DHHC PF01529.20 OWF51073.1 - 0.43 10.7 2.7 1.3 9.2 2.7 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase Neur_chan_LBD PF02931.23 OWF51074.1 - 1.1e-44 152.5 2.7 1.5e-44 152.0 2.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51074.1 - 2.1e-24 86.9 4.8 1.1e-22 81.3 0.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF51075.1 - 1.1e-35 123.1 1.0 1.8e-35 122.3 1.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51075.1 - 1.9e-22 80.5 4.9 1.3e-21 77.7 1.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 OWF51075.1 - 0.053 12.9 4.0 0.38 10.1 4.4 1.9 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF1656 PF07869.12 OWF51075.1 - 0.1 12.6 0.4 0.1 12.6 0.4 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1656) Bac_small_YrzI PF09501.10 OWF51075.1 - 0.76 9.9 3.0 4.9 7.4 2.0 2.3 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) zf-C2H2 PF00096.26 OWF51076.1 - 2.3e-45 150.6 149.6 1.6e-06 28.3 0.8 19.3 19 0 0 19 19 19 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF51076.1 - 5.3e-45 148.2 140.1 0.00013 22.5 0.4 19.4 19 0 0 19 19 19 17 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF51076.1 - 6.6e-38 127.5 125.8 1.1e-08 35.1 0.9 19.7 21 0 0 21 21 21 12 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF51076.1 - 7.8e-20 70.6 109.0 0.0051 17.1 0.8 16.4 16 0 0 16 16 16 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF51076.1 - 9e-16 57.7 109.0 0.00016 22.0 0.3 16.5 16 0 0 16 16 16 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF51076.1 - 5.8e-11 42.1 126.8 3.7e-05 23.6 0.6 16.6 17 1 0 17 17 16 9 C2H2-type zinc finger FOXP-CC PF16159.5 OWF51076.1 - 0.0051 17.4 0.1 0.0051 17.4 0.1 8.5 9 2 2 11 11 11 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 OWF51076.1 - 0.015 15.0 1.2 0.015 15.0 1.2 12.2 13 0 0 13 13 13 0 zinc-finger C2H2-type DNA_ligase_ZBD PF03119.16 OWF51076.1 - 0.084 12.9 1.6 16 5.6 0.5 3.0 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1013 PF06242.11 OWF51076.1 - 0.1 12.6 3.1 0.43 10.6 3.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) BolA PF01722.18 OWF51076.1 - 0.4 11.0 17.9 4.6 7.6 0.1 6.5 5 2 1 6 6 6 0 BolA-like protein zf-C2H2_3rep PF18868.1 OWF51076.1 - 1.4 9.6 75.8 0.96 10.1 8.0 10.3 3 2 7 11 11 11 0 Zinc finger C2H2-type, 3 repeats HCO3_cotransp PF00955.21 OWF51077.1 - 7.2e-202 671.7 13.1 9.5e-202 671.3 13.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 OWF51077.1 - 3.6e-94 315.5 0.0 3.6e-94 315.5 0.0 3.2 4 0 0 4 4 4 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 OWF51077.1 - 0.0045 16.9 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7tm_1 PF00001.21 OWF51077.1 - 0.02 14.2 2.3 0.84 8.9 1.8 2.8 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) AMP-binding PF00501.28 OWF51078.1 - 1.3e-62 211.7 0.0 1.6e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4573 PF15140.6 OWF51079.1 - 7.9e-09 35.5 0.0 0.00016 21.5 0.0 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) SF3b10 PF07189.11 OWF51079.1 - 4.8 7.4 25.2 7.4 6.8 0.0 8.2 3 3 6 10 10 10 0 Splicing factor 3B subunit 10 (SF3b10) DUF4573 PF15140.6 OWF51080.1 - 8.2e-10 38.7 0.0 0.00013 21.8 0.0 2.9 1 1 1 3 3 3 3 Domain of unknown function (DUF4573) DUF4573 PF15140.6 OWF51081.1 - 2.6e-18 66.5 0.0 1.3e-09 38.1 0.0 3.2 1 1 1 3 3 3 3 Domain of unknown function (DUF4573) GCV_H PF01597.19 OWF51081.1 - 0.00021 21.2 0.3 15 5.5 0.0 4.8 3 1 0 4 4 4 3 Glycine cleavage H-protein zf-B_box PF00643.24 OWF51082.1 - 1.1e-10 41.5 23.6 2.2e-05 24.5 10.7 2.7 2 0 0 2 2 2 2 B-box zinc finger Fez1 PF06818.15 OWF51082.1 - 0.044 14.2 9.7 0.075 13.5 9.7 1.3 1 0 0 1 1 1 0 Fez1 IBR PF01485.21 OWF51082.1 - 0.18 12.0 17.2 0.19 12.0 5.0 2.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain MnmE_helical PF12631.7 OWF51082.1 - 0.29 11.3 4.2 0.5 10.5 4.2 1.3 1 0 0 1 1 1 0 MnmE helical domain HAUS6_N PF14661.6 OWF51082.1 - 0.32 10.5 6.0 0.54 9.8 6.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SAS4 PF15460.6 OWF51082.1 - 0.57 10.3 6.2 3.3 7.9 0.9 2.8 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 TMPIT PF07851.13 OWF51082.1 - 8.5 5.5 7.8 14 4.8 2.0 1.9 1 1 1 2 2 2 0 TMPIT-like protein zf-B_box PF00643.24 OWF51083.1 - 5.3e-11 42.5 23.0 2.6e-05 24.3 10.3 2.5 2 0 0 2 2 2 2 B-box zinc finger Fez1 PF06818.15 OWF51083.1 - 0.01 16.3 8.6 0.017 15.5 8.6 1.3 1 0 0 1 1 1 1 Fez1 HAUS6_N PF14661.6 OWF51083.1 - 0.13 11.9 4.8 0.21 11.1 4.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IBR PF01485.21 OWF51083.1 - 0.56 10.5 18.6 0.33 11.2 4.4 3.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DNA_topoisoIV PF00521.20 OWF51083.1 - 0.64 8.8 6.4 0.99 8.2 6.4 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A CdvA PF18822.1 OWF51083.1 - 3.5 7.5 8.5 1.2 9.0 1.3 2.8 2 1 1 3 3 3 0 CdvA-like coiled-coil domain zf-B_box PF00643.24 OWF51084.1 - 3.1e-11 43.2 23.2 1.2e-05 25.3 10.7 2.5 2 0 0 2 2 2 2 B-box zinc finger Fez1 PF06818.15 OWF51084.1 - 0.018 15.5 9.7 0.029 14.8 9.7 1.3 1 0 0 1 1 1 0 Fez1 IBR PF01485.21 OWF51084.1 - 0.065 13.5 17.0 0.081 13.2 4.6 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain MnmE_helical PF12631.7 OWF51084.1 - 0.14 12.3 4.2 0.22 11.7 4.2 1.2 1 0 0 1 1 1 0 MnmE helical domain HAUS6_N PF14661.6 OWF51084.1 - 0.14 11.7 6.0 0.24 11.0 6.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SAS4 PF15460.6 OWF51084.1 - 0.99 9.5 8.6 1.8 8.7 0.9 2.8 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 DNA_topoisoIV PF00521.20 OWF51084.1 - 1.7 7.4 7.3 2.6 6.9 7.3 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A TMPIT PF07851.13 OWF51084.1 - 4 6.6 8.4 3.1 7.0 3.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein LRR_6 PF13516.6 OWF51085.1 - 8.8e-28 94.0 15.8 0.0016 18.4 0.1 11.3 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 OWF51085.1 - 8.2e-14 51.5 0.9 0.038 14.4 0.1 6.7 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OWF51085.1 - 9.5e-12 44.6 0.8 2.7e-11 43.2 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF51085.1 - 1.6e-06 27.8 1.3 1.1e-05 25.2 1.3 2.5 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 OWF51085.1 - 1.5e-05 24.9 15.0 2 9.3 0.0 9.2 10 1 0 10 10 10 1 Leucine Rich Repeat Lin-8 PF03353.15 OWF51085.1 - 0.87 9.1 6.1 1.6 8.3 6.1 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.9 OWF51085.1 - 1.3 8.2 12.8 1.9 7.6 12.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAM220 PF15487.6 OWF51085.1 - 3.1 7.4 8.1 4.8 6.7 8.1 1.2 1 0 0 1 1 1 0 FAM220 family Pkinase PF00069.25 OWF51087.1 - 2.9e-73 246.5 0.1 6.1e-73 245.4 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51087.1 - 3.7e-37 128.0 0.0 6.6e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DCX PF03607.17 OWF51087.1 - 7.4e-30 102.8 0.0 5.9e-17 61.5 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Kinase-like PF14531.6 OWF51087.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OWF51087.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OWF51089.1 - 1.4e-68 231.1 0.1 4.3e-67 226.3 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51089.1 - 4.4e-34 117.9 0.1 2.2e-33 115.7 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase cNMP_binding PF00027.29 OWF51089.1 - 1.4e-29 102.0 0.7 2.6e-17 62.6 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain APH PF01636.23 OWF51089.1 - 0.00099 19.1 0.0 0.0039 17.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Med4 PF10018.9 OWF51089.1 - 0.002 17.8 1.6 0.0033 17.1 1.6 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Kinase-like PF14531.6 OWF51089.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pedibin PF08182.11 OWF51089.1 - 4.4 7.2 7.0 12 5.8 0.1 2.6 2 0 0 2 2 2 0 Pedibin/Hym-346 family AAA PF00004.29 OWF51090.1 - 1.4e-12 48.1 0.0 4.4e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF51090.1 - 4.7e-08 33.1 0.0 3.1e-07 30.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OWF51090.1 - 7.6e-06 26.0 0.0 4.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OWF51090.1 - 7.6e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 OWF51090.1 - 0.00012 22.0 0.0 0.0025 17.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 OWF51090.1 - 0.00014 22.4 2.4 0.00037 21.0 0.0 3.0 4 0 0 4 4 2 1 AAA domain dNK PF01712.19 OWF51090.1 - 0.00046 20.1 0.5 0.74 9.6 0.0 2.6 2 0 0 2 2 2 2 Deoxynucleoside kinase SMYLE_N PF18615.1 OWF51090.1 - 0.0012 18.5 1.2 0.0024 17.5 1.2 1.5 1 0 0 1 1 1 1 Short myomegalin-like EB1 binding proteins, N-terminal domain AAA_33 PF13671.6 OWF51090.1 - 0.0015 18.7 0.1 0.0073 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OWF51090.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OWF51090.1 - 0.0019 17.9 0.1 0.0056 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF51090.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF51090.1 - 0.0043 17.3 0.4 0.13 12.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF51090.1 - 0.0051 17.2 0.2 0.032 14.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 OWF51090.1 - 0.015 15.6 0.0 0.057 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OWF51090.1 - 0.017 15.1 0.7 0.3 11.0 0.0 3.0 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 OWF51090.1 - 0.021 14.8 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OWF51090.1 - 0.031 14.0 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 OWF51090.1 - 0.039 13.2 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 OWF51090.1 - 0.042 14.3 0.8 0.53 10.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OWF51090.1 - 0.044 14.3 0.2 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter TIP49 PF06068.13 OWF51090.1 - 0.067 12.4 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain RFC1 PF08519.12 OWF51090.1 - 0.071 13.3 2.2 0.11 12.7 0.3 2.2 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain AAA_25 PF13481.6 OWF51090.1 - 0.081 12.5 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 OWF51090.1 - 0.089 12.1 0.1 1.8 7.9 0.0 2.7 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 PIP5K PF01504.18 OWF51091.1 - 4.1e-43 147.6 2.4 3.6e-34 118.3 0.9 2.9 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OWF51091.1 - 2.3e-26 92.5 0.1 4e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OWF51091.1 - 3.6e-17 62.3 11.7 1.1e-16 60.7 11.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger DEP PF00610.21 OWF51091.1 - 1.5e-16 60.2 0.0 3.3e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Arc_PepC_II PF06847.11 OWF51091.1 - 0.0014 19.1 0.4 0.029 14.9 0.0 2.9 2 0 0 2 2 2 1 Archaeal Peptidase A24 C-terminus Type II DUF148 PF02520.17 OWF51091.1 - 0.47 10.6 3.5 0.4 10.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 Neur_chan_LBD PF02931.23 OWF51092.1 - 5.6e-22 78.3 0.0 8.5e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51092.1 - 8e-15 55.6 1.5 1e-14 55.2 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 OWF51092.1 - 0.1 12.0 3.1 0.17 11.3 3.1 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) LicD PF04991.13 OWF51093.1 - 3.2e-09 37.3 0.0 7.3e-08 32.8 0.0 2.7 2 1 1 3 3 3 1 LicD family DUF3573 PF12097.8 OWF51094.1 - 0.078 11.8 0.1 0.75 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Surfac_D-trimer PF09006.11 OWF51094.1 - 0.086 12.7 1.0 0.16 11.9 1.0 1.3 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Glycos_transf_1 PF00534.20 OWF51095.1 - 1.1e-13 51.1 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OWF51095.1 - 3.7e-11 43.6 0.0 6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OWF51095.1 - 3.5e-10 40.1 0.0 1.2e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 IRF-2BP1_2 PF11261.8 OWF51095.1 - 0.1 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger zf-B_box PF00643.24 OWF51096.1 - 3.4e-10 39.9 26.3 2.1e-08 34.2 11.4 4.0 4 0 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF51096.1 - 8.2e-08 32.1 12.1 8.2e-08 32.1 12.1 3.5 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF51096.1 - 9.5e-06 25.4 16.0 9.5e-06 25.4 16.0 3.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51096.1 - 5.4e-05 23.4 14.0 5.4e-05 23.4 14.0 3.7 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF51096.1 - 0.00052 20.1 12.5 0.00052 20.1 12.5 4.0 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF51096.1 - 0.0047 16.9 15.2 0.0047 16.9 15.2 4.0 3 1 0 3 3 2 1 zinc-RING finger domain KaiA PF07688.12 OWF51096.1 - 0.019 15.1 0.1 0.048 13.8 0.1 1.6 1 0 0 1 1 1 0 KaiA C-terminal domain HR1 PF02185.16 OWF51096.1 - 0.019 15.0 2.7 2.7 8.2 0.3 2.7 2 0 0 2 2 2 0 Hr1 repeat DUF4806 PF16064.5 OWF51096.1 - 0.12 12.7 1.0 11 6.5 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) MIT PF04212.18 OWF51096.1 - 0.13 12.4 0.1 0.4 10.8 0.1 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Phage_GPO PF05929.11 OWF51096.1 - 0.71 9.4 6.4 1.9 8.0 0.9 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase REV PF00424.18 OWF51096.1 - 6.8 6.8 9.6 0.45 10.6 3.1 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Ion_trans_2 PF07885.16 OWF51097.1 - 5.3e-36 122.4 19.2 6.9e-19 67.6 1.5 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF51097.1 - 5.8e-09 35.5 8.6 6.9e-06 25.5 0.4 2.3 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 OWF51097.1 - 0.0035 17.2 0.4 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Ligand-gated ion channel RAMP4 PF06624.12 OWF51097.1 - 0.19 11.8 0.5 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 PMP1_2 PF08114.11 OWF51097.1 - 0.42 10.4 4.4 13 5.6 0.5 2.6 2 0 0 2 2 2 0 ATPase proteolipid family Glyco_transf_21 PF13506.6 OWF51098.1 - 1.7e-46 157.8 0.0 2.2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OWF51098.1 - 8.7e-27 94.5 0.0 1.1e-26 94.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OWF51098.1 - 2.7e-10 40.5 1.0 4.4e-10 39.8 1.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OWF51098.1 - 2.1e-08 34.2 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 CAP_GLY PF01302.25 OWF51099.1 - 2.4e-44 149.2 2.0 8.9e-22 76.9 0.1 2.4 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 OWF51099.1 - 8.2e-09 35.1 15.6 9.7e-07 28.5 5.7 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle TMF_TATA_bd PF12325.8 OWF51099.1 - 0.0013 19.0 15.8 0.0013 19.0 15.8 12.2 2 1 11 13 13 13 2 TATA element modulatory factor 1 TATA binding BST2 PF16716.5 OWF51099.1 - 0.0099 16.4 10.1 0.0099 16.4 10.1 13.2 3 1 10 14 14 14 3 Bone marrow stromal antigen 2 DUF641 PF04859.12 OWF51101.1 - 0.0011 19.3 0.2 0.0016 18.8 0.2 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) MscS_porin PF12795.7 OWF51101.1 - 0.0025 17.4 2.0 0.0033 17.0 2.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 OWF51101.1 - 0.0036 16.6 0.2 0.0052 16.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF3158 PF11358.8 OWF51101.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) SlyX PF04102.12 OWF51101.1 - 0.019 15.6 0.4 0.029 15.0 0.4 1.2 1 0 0 1 1 1 0 SlyX Bacillus_HBL PF05791.11 OWF51101.1 - 0.042 13.7 1.1 0.061 13.1 1.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Gp58 PF07902.11 OWF51101.1 - 0.045 12.1 1.8 0.064 11.5 1.8 1.1 1 0 0 1 1 1 0 gp58-like protein BAP PF06639.11 OWF51101.1 - 0.056 13.8 0.1 0.29 11.5 0.0 2.3 2 1 0 2 2 2 0 Basal layer antifungal peptide (BAP) Mod_r PF07200.13 OWF51101.1 - 0.099 12.7 0.9 0.15 12.2 0.9 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Tup_N PF08581.10 OWF51101.1 - 0.11 12.8 0.5 0.17 12.2 0.5 1.2 1 0 0 1 1 1 0 Tup N-terminal ATG16 PF08614.11 OWF51101.1 - 0.15 12.3 1.0 0.21 11.8 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4763 PF15960.5 OWF51101.1 - 0.15 11.3 0.3 0.22 10.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CLZ PF16526.5 OWF51101.1 - 0.21 12.0 0.4 0.37 11.2 0.4 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PspA_IM30 PF04012.12 OWF51101.1 - 0.21 11.1 0.4 0.29 10.7 0.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family IFT57 PF10498.9 OWF51101.1 - 0.28 10.1 1.4 0.38 9.7 1.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Csm1_N PF18504.1 OWF51101.1 - 0.35 11.2 0.9 5.7 7.4 0.1 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain GIT_CC PF16559.5 OWF51101.1 - 0.58 10.1 2.1 0.73 9.8 1.1 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HemX PF04375.14 OWF51102.1 - 0.00047 19.5 2.2 0.00058 19.2 2.2 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Fib_alpha PF08702.10 OWF51102.1 - 0.00096 19.4 14.0 0.0034 17.6 3.5 1.6 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family ATG16 PF08614.11 OWF51102.1 - 0.0017 18.7 3.9 0.0024 18.1 3.9 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Mod_r PF07200.13 OWF51102.1 - 0.0029 17.7 3.9 0.0041 17.2 3.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Bacillus_HBL PF05791.11 OWF51102.1 - 0.0035 17.2 5.3 0.0048 16.7 5.3 1.1 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF3450 PF11932.8 OWF51102.1 - 0.0051 16.2 1.1 0.0068 15.7 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF641 PF04859.12 OWF51102.1 - 0.0055 17.0 0.7 0.0094 16.3 0.7 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Spc7 PF08317.11 OWF51102.1 - 0.0083 15.0 1.8 0.011 14.6 1.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein WXG100 PF06013.12 OWF51102.1 - 0.018 15.3 6.5 0.069 13.4 0.8 2.2 1 1 0 2 2 2 0 Proteins of 100 residues with WXG HIP1_clath_bdg PF16515.5 OWF51102.1 - 0.019 15.5 5.3 0.028 15.0 5.3 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HAUS-augmin3 PF14932.6 OWF51102.1 - 0.025 14.2 3.3 0.032 13.8 3.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CEP63 PF17045.5 OWF51102.1 - 0.043 13.7 3.3 0.044 13.7 1.6 1.6 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa zf-BED PF02892.15 OWF51102.1 - 0.05 13.6 1.8 0.48 10.5 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger Atg14 PF10186.9 OWF51102.1 - 0.053 12.6 1.2 0.071 12.2 1.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 OWF51102.1 - 0.053 13.1 0.5 0.074 12.7 0.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fez1 PF06818.15 OWF51102.1 - 0.059 13.8 3.5 0.18 12.2 3.5 1.6 1 1 0 1 1 1 0 Fez1 DUF1664 PF07889.12 OWF51102.1 - 0.073 13.1 1.9 0.11 12.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2046 PF09755.9 OWF51102.1 - 0.078 12.2 0.3 0.11 11.7 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) FPP PF05911.11 OWF51102.1 - 0.08 11.1 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Phage_GP20 PF06810.11 OWF51102.1 - 0.08 12.7 0.9 0.12 12.1 0.9 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 ADIP PF11559.8 OWF51102.1 - 0.084 13.0 6.4 0.13 12.4 6.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 OWF51102.1 - 0.093 12.3 2.0 0.13 11.8 2.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein Fzo_mitofusin PF04799.13 OWF51102.1 - 0.093 12.3 2.7 0.14 11.7 2.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF745 PF05335.13 OWF51102.1 - 0.11 12.2 1.4 0.15 11.8 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 OWF51102.1 - 0.11 12.5 2.1 0.16 12.0 2.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 OWF51102.1 - 0.11 12.5 4.1 0.15 12.1 4.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 OWF51102.1 - 0.12 13.0 1.9 0.16 12.5 1.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 OWF51102.1 - 0.15 12.4 3.6 0.21 11.9 3.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PspA_IM30 PF04012.12 OWF51102.1 - 0.15 11.6 1.3 0.22 11.1 1.3 1.2 1 0 0 1 1 1 0 PspA/IM30 family Tup_N PF08581.10 OWF51102.1 - 0.15 12.4 2.7 0.4 11.0 2.7 1.7 1 1 0 1 1 1 0 Tup N-terminal RmuC PF02646.16 OWF51102.1 - 0.17 11.0 3.5 0.2 10.8 3.5 1.1 1 0 0 1 1 1 0 RmuC family Surfac_D-trimer PF09006.11 OWF51102.1 - 0.17 11.8 6.2 1.1 9.2 0.7 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Med9 PF07544.13 OWF51102.1 - 0.21 11.7 1.6 0.31 11.1 1.6 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Csm1_N PF18504.1 OWF51102.1 - 0.25 11.7 5.7 1.3 9.4 0.4 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain Not3 PF04065.15 OWF51102.1 - 0.26 10.7 1.5 0.35 10.3 1.5 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component IFT57 PF10498.9 OWF51102.1 - 0.63 9.0 5.1 0.88 8.5 5.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF16 PF01519.16 OWF51102.1 - 0.77 10.3 4.6 1.2 9.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 CLZ PF16526.5 OWF51102.1 - 0.92 9.9 4.5 2.6 8.5 0.8 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 OWF51102.1 - 1.3 9.7 4.0 1.9 9.1 1.8 2.1 2 0 0 2 2 2 0 Initiation control protein YabA FliJ PF02050.16 OWF51102.1 - 1.7 8.9 7.3 2.7 8.2 7.3 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Trimer_CC PF08954.11 OWF51102.1 - 3.7 7.2 10.7 6.1 6.5 1.1 2.6 1 1 1 2 2 2 0 Trimerisation motif SlyX PF04102.12 OWF51102.1 - 4.3 8.0 10.9 1.5 9.5 3.6 2.1 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 OWF51102.1 - 4.8 7.0 5.0 4.1 7.2 0.9 2.3 1 1 1 2 2 2 0 Septum formation initiator BST2 PF16716.5 OWF51102.1 - 6 7.5 11.2 14 6.4 11.2 1.5 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 Wyosine_form PF08608.12 OWF51103.1 - 1.2e-27 96.1 0.1 3.7e-27 94.5 0.1 1.9 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 OWF51103.1 - 1.3e-23 84.2 0.0 3.3e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 OWF51103.1 - 2.5e-22 79.7 0.1 6.9e-22 78.2 0.1 1.8 1 0 0 1 1 1 1 Flavodoxin Hydrolase PF00702.26 OWF51103.1 - 0.049 13.9 0.0 5.3 7.3 0.0 3.1 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Adaptin_binding PF10199.9 OWF51103.1 - 0.65 10.6 6.6 2 9.0 6.1 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DED PF01335.21 OWF51104.1 - 1.7e-12 47.4 1.1 1.7e-12 47.4 1.1 2.7 2 0 0 2 2 2 1 Death effector domain Nucleic_acid_bd PF13820.6 OWF51104.1 - 0.044 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative nucleic acid-binding region DUF3450 PF11932.8 OWF51104.1 - 5.4 6.2 8.0 0.44 9.8 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DED PF01335.21 OWF51105.1 - 1.4e-13 51.0 0.3 1.4e-13 51.0 0.3 3.0 4 0 0 4 4 4 1 Death effector domain Nucleic_acid_bd PF13820.6 OWF51105.1 - 0.0082 16.0 0.7 0.036 13.9 0.1 2.4 2 0 0 2 2 2 1 Putative nucleic acid-binding region DED PF01335.21 OWF51106.1 - 1.8e-14 53.8 0.3 1.8e-14 53.8 0.3 2.8 3 0 0 3 3 3 1 Death effector domain Nucleic_acid_bd PF13820.6 OWF51106.1 - 0.00065 19.6 0.0 0.00065 19.6 0.0 2.8 1 1 2 3 3 3 1 Putative nucleic acid-binding region L1R_F9L PF02442.17 OWF51106.1 - 0.019 14.8 0.7 0.049 13.5 0.7 1.6 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Ion_trans PF00520.31 OWF51107.1 - 8e-20 71.1 15.5 1.2e-19 70.5 15.5 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OWF51107.1 - 5e-14 52.1 0.1 1.1e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OWF51107.1 - 7.3e-06 25.9 2.6 1.7e-05 24.7 2.6 1.6 1 0 0 1 1 1 1 Ion channel OmpH PF03938.14 OWF51108.1 - 0.0042 17.4 2.3 0.006 16.9 2.3 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4972 PF16342.5 OWF51108.1 - 0.011 15.4 2.0 0.011 15.4 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) TPR_MLP1_2 PF07926.12 OWF51108.1 - 0.017 15.1 8.7 0.026 14.6 8.7 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 OWF51108.1 - 0.025 14.8 8.4 0.035 14.3 8.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) USP8_interact PF08941.10 OWF51108.1 - 0.064 13.1 1.4 0.097 12.5 1.4 1.2 1 0 0 1 1 1 0 USP8 interacting ADIP PF11559.8 OWF51108.1 - 0.56 10.3 9.1 0.82 9.7 9.1 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding BST2 PF16716.5 OWF51108.1 - 1.1 9.8 12.0 1.7 9.3 12.0 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF16 PF01519.16 OWF51108.1 - 1.3 9.6 6.3 2.1 8.9 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 TolA_bind_tri PF16331.5 OWF51108.1 - 6.2 7.0 14.2 12 6.0 6.9 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation DASH_Spc34 PF08657.10 OWF51108.1 - 7.4 6.3 9.6 17 5.1 3.8 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 Bacillus_HBL PF05791.11 OWF51111.1 - 0.0062 16.4 0.9 0.0085 15.9 0.9 1.1 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) BST2 PF16716.5 OWF51111.1 - 0.02 15.5 1.4 0.033 14.8 1.4 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF4972 PF16342.5 OWF51111.1 - 0.035 13.8 0.2 0.06 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF3450 PF11932.8 OWF51111.1 - 0.046 13.0 2.1 0.066 12.5 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 OWF51111.1 - 0.074 13.7 1.9 0.11 13.1 1.9 1.2 1 0 0 1 1 1 0 SlyX ABC_tran_CTD PF16326.5 OWF51111.1 - 0.12 12.6 0.8 1.4 9.2 0.2 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 OWF51112.1 - 3.8e-05 23.9 36.8 0.062 13.5 5.8 4.2 1 1 4 5 5 5 3 Fibrinogen alpha/beta chain family ATG16 PF08614.11 OWF51112.1 - 0.00055 20.2 43.2 0.073 13.3 17.4 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 OWF51112.1 - 0.0017 18.1 30.1 0.003 17.3 9.9 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF16 PF01519.16 OWF51112.1 - 0.0042 17.5 39.4 0.11 13.0 11.3 3.2 1 1 2 3 3 3 2 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 OWF51112.1 - 0.0047 16.9 7.8 0.0047 16.9 7.8 3.1 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Cast PF10174.9 OWF51112.1 - 0.0052 15.1 21.7 0.0072 14.6 21.7 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ADIP PF11559.8 OWF51112.1 - 0.0076 16.4 45.7 0.28 11.2 21.1 2.5 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Filament PF00038.21 OWF51112.1 - 0.02 14.5 33.9 1.1 8.8 8.1 2.6 1 1 1 2 2 2 0 Intermediate filament protein HNH_repeat PF18780.1 OWF51112.1 - 0.031 14.1 0.0 6.5e+02 0.3 0.0 6.4 9 0 0 9 9 9 0 Homing endonuclease repeat HAUS-augmin3 PF14932.6 OWF51112.1 - 0.035 13.7 43.0 0.33 10.5 22.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 WEMBL PF05701.11 OWF51112.1 - 0.048 12.4 22.9 0.068 11.9 22.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.9 OWF51112.1 - 0.05 13.6 34.3 0.36 10.9 11.1 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OWF51112.1 - 0.085 13.3 28.9 0.13 12.7 18.3 2.2 1 1 1 2 2 2 0 Fez1 Lebercilin PF15619.6 OWF51112.1 - 0.15 11.7 35.6 0.11 12.2 20.5 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 OWF51112.1 - 0.22 10.4 34.6 0.15 10.9 20.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CEP63 PF17045.5 OWF51112.1 - 0.31 10.9 31.7 0.65 9.9 12.3 2.1 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF4407 PF14362.6 OWF51112.1 - 0.35 10.2 33.2 1.2 8.4 33.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 OWF51112.1 - 0.46 10.8 28.2 6.2 7.2 5.1 3.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) OmpH PF03938.14 OWF51112.1 - 0.64 10.4 39.9 1.8e+04 -9.1 39.9 2.6 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) DUF812 PF05667.11 OWF51112.1 - 0.73 8.6 30.0 1.1 8.1 30.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HIP1_clath_bdg PF16515.5 OWF51112.1 - 0.73 10.5 48.6 1.4 9.6 8.7 4.4 2 1 4 6 6 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 OWF51112.1 - 0.75 8.8 28.3 18 4.3 27.5 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med9 PF07544.13 OWF51112.1 - 0.82 9.8 29.6 2.3 8.4 6.1 3.7 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Prominin PF05478.11 OWF51112.1 - 0.97 7.3 23.0 1.3 6.9 23.0 1.1 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 OWF51112.1 - 2 6.2 15.0 3.5 5.4 15.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 OWF51112.1 - 2.2 8.7 26.6 0.57 10.6 18.5 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.6 OWF51112.1 - 2.4 6.7 20.0 4.2 5.9 20.0 1.3 1 0 0 1 1 1 0 AAA domain SCO1-SenC PF02630.14 OWF51112.1 - 2.8 7.9 16.3 4.2 7.3 3.3 3.0 1 1 2 3 3 3 0 SCO1/SenC NPV_P10 PF05531.12 OWF51112.1 - 3 8.4 44.1 0.76 10.3 10.1 4.2 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 OWF51112.1 - 3.1 7.9 40.4 0.39 10.8 32.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 OWF51112.1 - 4.1 6.8 38.2 9 5.7 37.7 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tup_N PF08581.10 OWF51112.1 - 4.7 7.6 31.9 33 4.9 7.4 5.7 1 1 4 5 5 5 0 Tup N-terminal Arylsulfotran_N PF17425.2 OWF51112.1 - 5.6 7.1 19.7 9.4 6.3 1.0 3.5 1 1 3 4 4 4 0 Arylsulfotransferase Ig-like domain DUF2203 PF09969.9 OWF51112.1 - 6.2 7.6 18.6 14 6.4 5.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FPP PF05911.11 OWF51112.1 - 8.4 4.4 30.2 11 4.0 30.2 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF5082 PF16888.5 OWF51112.1 - 9.1 6.6 30.2 13 6.1 11.1 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) AIP3 PF03915.13 OWF51112.1 - 9.1 5.2 24.9 14 4.6 24.9 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Ion_trans PF00520.31 OWF51113.1 - 1.5e-20 73.5 14.7 2.3e-20 72.9 14.7 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OWF51113.1 - 2e-15 56.6 0.1 4.5e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OWF51113.1 - 4e-06 26.7 2.7 1e-05 25.4 2.7 1.7 1 0 0 1 1 1 1 Ion channel DUF5095 PF17016.5 OWF51113.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Ion_trans PF00520.31 OWF51114.1 - 1.1e-15 57.5 10.9 1.5e-15 57.1 10.9 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5095 PF17016.5 OWF51114.1 - 0.034 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Ion_trans_2 PF07885.16 OWF51114.1 - 0.13 12.3 1.5 0.44 10.5 1.5 1.9 1 1 0 1 1 1 0 Ion channel KOW PF00467.29 OWF51115.1 - 0.16 12.0 4.9 20 5.3 0.0 4.9 6 1 1 7 7 7 0 KOW motif HTH_57 PF18679.1 OWF51115.1 - 0.65 10.3 8.6 3.1 8.1 1.0 3.9 2 2 0 2 2 2 0 ThcOx helix turn helix domain DUF4349 PF14257.6 OWF51115.1 - 1.2 8.5 9.4 2.8 7.3 0.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) Med3 PF11593.8 OWF51115.1 - 1.4 8.1 4.0 7.6 5.6 0.2 2.6 2 1 1 3 3 3 0 Mediator complex subunit 3 fungal DUF1495 PF07381.11 OWF51116.1 - 0.011 15.6 4.9 60 3.6 0.0 5.0 3 2 2 5 5 5 0 Winged helix DNA-binding domain (DUF1495) Complex1_LYR_1 PF13232.6 OWF51116.1 - 0.83 10.3 11.7 3.5 8.3 1.2 3.5 1 1 3 4 4 4 0 Complex1_LYR-like CDP-OH_P_tran_2 PF08009.11 OWF51117.1 - 0.039 13.9 12.7 36 4.4 0.4 7.5 7 2 1 8 8 8 0 CDP-alcohol phosphatidyltransferase 2 DSBA PF01323.20 OWF51117.1 - 0.1 12.3 5.9 12 5.6 0.1 4.0 2 2 1 4 4 4 0 DSBA-like thioredoxin domain SF3A2 PF16835.5 OWF51118.1 - 0.031 14.7 5.4 1.5e+02 2.8 0.0 6.6 5 4 1 6 6 6 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Ig_3 PF13927.6 OWF51120.1 - 6.8e-13 49.0 4.7 1.4e-12 48.0 4.7 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF51120.1 - 8.5e-12 45.0 0.3 1.4e-11 44.3 0.3 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 OWF51120.1 - 3.8e-11 43.0 3.5 6.7e-11 42.2 3.5 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF51120.1 - 2.7e-09 37.2 2.2 5.5e-09 36.2 2.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain DED PF01335.21 OWF51120.1 - 4.6e-07 30.1 0.2 0.0037 17.5 0.0 2.3 2 0 0 2 2 2 2 Death effector domain V-set PF07686.17 OWF51120.1 - 1.3e-06 28.5 2.7 1e-05 25.7 2.7 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain DnaB_2 PF07261.11 OWF51120.1 - 0.04 13.7 1.0 7 6.5 0.1 2.6 2 1 0 2 2 2 0 Replication initiation and membrane attachment Glyco_hydro_42 PF02449.15 OWF51120.1 - 0.046 13.1 0.1 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase Gcd10p PF04189.13 OWF51120.1 - 0.086 11.9 0.7 0.49 9.5 0.2 2.0 2 0 0 2 2 2 0 Gcd10p family Abp2 PF09441.10 OWF51120.1 - 0.15 12.1 0.1 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 ARS binding protein 2 PRESAN PF09687.10 OWF51120.1 - 0.62 10.6 6.1 13 6.4 0.5 2.8 2 1 0 2 2 2 0 Plasmodium RESA N-terminal FeThRed_A PF02941.15 OWF51121.1 - 0.097 12.8 0.0 41 4.4 0.0 3.6 4 1 0 4 4 4 0 Ferredoxin thioredoxin reductase variable alpha chain FTO_CTD PF12934.7 OWF51121.1 - 2.3 8.0 7.7 4.1 7.1 0.1 3.7 3 1 1 4 4 4 0 FTO C-terminal domain Myco_19_kDa PF05481.12 OWF51121.1 - 8.7 6.7 11.3 35 4.7 1.0 4.2 1 1 3 4 4 4 0 Mycobacterium 19 kDa lipoprotein antigen Ion_trans PF00520.31 OWF51122.1 - 2.1e-41 141.8 10.1 3e-41 141.3 10.1 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF51122.1 - 1.7e-27 95.6 0.6 3.9e-27 94.4 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Shal-type PF11601.8 OWF51122.1 - 3.5e-15 55.2 9.2 7.8e-15 54.1 9.2 1.6 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal Ion_trans_2 PF07885.16 OWF51122.1 - 3.6e-12 46.1 5.5 3.6e-12 46.1 5.5 2.4 2 0 0 2 2 2 1 Ion channel DUF3399 PF11879.8 OWF51122.1 - 1.4e-09 38.2 1.2 2.9e-09 37.2 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) BTB_3 PF16017.5 OWF51122.1 - 0.00091 19.3 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain WW_FCH_linker PF16623.5 OWF51122.1 - 0.069 13.9 1.2 0.21 12.3 1.2 1.8 1 0 0 1 1 1 0 Unstructured linker region between on GAS7 protein G0-G1_switch_2 PF15103.6 OWF51122.1 - 0.08 13.4 0.0 0.98 9.9 0.2 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 PKD_channel PF08016.12 OWF51122.1 - 0.27 9.9 4.8 0.39 9.3 4.8 1.2 1 0 0 1 1 1 0 Polycystin cation channel NTP_transferase PF00483.23 OWF51123.1 - 1.1e-54 185.6 0.0 1.7e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OWF51123.1 - 8.7e-11 41.1 7.9 7.1e-09 35.1 3.3 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OWF51123.1 - 2.3e-10 41.0 0.0 3.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OWF51123.1 - 8.9e-06 25.4 6.1 4e-05 23.3 1.9 3.6 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 OWF51123.1 - 0.00035 20.6 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase DUF4954 PF16314.5 OWF51123.1 - 0.00062 18.0 0.2 0.00093 17.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 OWF51123.1 - 0.08 11.9 0.2 0.7 8.8 0.1 2.1 2 0 0 2 2 2 0 L-fucokinase IspD PF01128.19 OWF51123.1 - 0.17 11.6 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase WASH_WAHD PF11945.8 OWF51124.1 - 1.3e-98 330.1 2.1 1.8e-98 329.7 2.1 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex XhlA PF10779.9 OWF51124.1 - 0.077 13.2 0.3 0.22 11.7 0.3 1.8 1 0 0 1 1 1 0 Haemolysin XhlA WH2 PF02205.20 OWF51124.1 - 2 8.4 7.1 0.39 10.6 0.6 2.5 2 0 0 2 2 2 0 WH2 motif Glyco_transf_90 PF05686.12 OWF51128.1 - 3.3e-104 348.9 4.2 4e-104 348.7 4.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OWF51128.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-NOSIP PF15906.5 OWF51128.1 - 0.082 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein EB PF01683.18 OWF51128.1 - 1.8 8.9 6.1 20 5.5 0.8 2.9 3 0 0 3 3 3 0 EB module DUF4972 PF16342.5 OWF51128.1 - 6.8 6.4 5.7 16 5.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) DUF19 PF01579.18 OWF51129.1 - 0.00022 21.0 8.1 0.0016 18.3 8.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF19) RPN7 PF10602.9 OWF51129.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 CN_hydrolase PF00795.22 OWF51131.1 - 1.3e-63 214.8 0.0 1.7e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 OWF51131.1 - 1.4e-16 61.0 0.1 3.5e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OWF51131.1 - 0.012 16.1 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding LPD29 PF18847.1 OWF51131.1 - 0.15 13.0 0.1 0.39 11.7 0.1 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 MFS_1 PF07690.16 OWF51136.1 - 1.4e-17 63.7 26.2 1.4e-17 63.7 26.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_22 PF13383.6 OWF51137.1 - 1.8e-07 31.0 0.1 1.9e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF51137.1 - 0.00012 22.2 0.5 0.00018 21.6 0.4 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain TNFR_c6 PF00020.18 OWF51139.1 - 3.6e-34 116.9 96.9 3.9e-08 33.6 9.4 7.0 7 0 0 7 7 7 6 TNFR/NGFR cysteine-rich region DUF3139 PF11337.8 OWF51139.1 - 0.044 14.4 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Peptidase_S49_N PF08496.10 OWF51139.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LRR_8 PF13855.6 OWF51140.1 - 6.4e-25 86.7 25.1 1.3e-08 34.4 1.1 5.5 5 1 0 5 5 5 4 Leucine rich repeat TIR PF01582.20 OWF51140.1 - 1.7e-17 63.8 0.1 2.8e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF51140.1 - 4.3e-14 52.4 24.7 0.00057 20.2 0.6 5.8 3 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF51140.1 - 1.2e-10 41.4 1.8 1.4e-05 25.0 0.5 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 OWF51140.1 - 7.5e-10 39.5 0.0 1.3e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF51140.1 - 2e-07 30.7 6.1 0.046 13.2 0.1 3.6 1 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 OWF51140.1 - 1.7 8.9 8.6 72 3.8 0.2 4.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 OWF51141.1 - 1.8e-24 85.2 27.7 2.4e-08 33.6 1.6 5.5 4 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OWF51141.1 - 6e-12 45.6 26.9 0.0078 16.6 0.7 6.5 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF51141.1 - 9.8e-11 41.7 3.1 1.1e-05 25.4 1.2 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF51141.1 - 4.5e-08 32.8 5.8 0.03 13.8 0.1 3.7 1 1 3 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 OWF51142.1 - 1.1e-34 117.9 44.7 3.8e-09 36.2 2.7 7.8 5 2 1 7 7 7 7 Leucine rich repeat TIR PF01582.20 OWF51142.1 - 7.9e-18 64.9 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF51142.1 - 1.5e-15 57.1 38.9 0.0019 18.6 1.4 8.2 3 1 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF51142.1 - 2e-14 53.6 14.9 1.3e-05 25.2 0.5 4.3 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 OWF51142.1 - 2.9e-10 40.8 0.0 6.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF51142.1 - 4.6e-09 36.0 8.7 0.0066 16.0 1.3 4.8 1 1 3 5 5 5 3 Leucine-rich repeat TIR PF01582.20 OWF51143.1 - 1.1e-11 44.8 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF51143.1 - 1.3e-06 29.0 0.0 2.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF51143.1 - 0.00024 20.8 3.1 0.00065 19.4 3.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_8 PF13855.6 OWF51144.1 - 2e-23 81.9 25.1 3.4e-10 39.5 2.5 6.1 3 3 3 6 6 6 5 Leucine rich repeat LRR_5 PF13306.6 OWF51144.1 - 2.4e-13 50.2 16.3 2.1e-06 27.7 1.8 3.1 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF51144.1 - 2.4e-06 27.8 35.6 0.0022 18.4 3.8 6.5 3 3 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF51144.1 - 0.0022 17.5 4.8 0.03 13.8 0.1 2.8 2 1 1 3 3 3 2 Leucine-rich repeat Kelch_4 PF13418.6 OWF51144.1 - 0.24 11.4 1.2 0.84 9.7 0.1 2.4 3 0 0 3 3 3 0 Galactose oxidase, central domain MFS_1 PF07690.16 OWF51145.1 - 9.4e-14 51.1 27.2 2.1e-13 50.0 27.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF51146.1 - 1.9e-18 66.5 47.1 3.7e-17 62.3 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF51146.1 - 0.00022 20.2 1.4 0.00022 20.2 1.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TcpE PF12648.7 OWF51146.1 - 10 6.8 7.3 25 5.5 0.1 3.2 3 0 0 3 3 3 0 TcpE family Amino_oxidase PF01593.24 OWF51147.1 - 1e-64 219.5 0.0 1.7e-64 218.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF51147.1 - 2.7e-14 53.1 1.2 6.3e-14 52.0 1.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF51147.1 - 2e-05 23.9 0.1 4e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF51147.1 - 0.00081 18.2 1.2 0.0014 17.4 1.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OWF51147.1 - 0.0013 18.1 1.0 0.0023 17.2 0.4 1.7 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 OWF51147.1 - 0.0018 17.6 1.2 0.0033 16.8 1.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OWF51147.1 - 0.0043 16.3 2.8 0.0067 15.7 0.9 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF51147.1 - 0.0048 16.5 2.1 0.0074 15.9 2.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OWF51147.1 - 0.012 14.9 0.9 0.03 13.6 0.9 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF51147.1 - 0.022 14.1 2.0 0.045 13.1 2.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OWF51147.1 - 0.026 13.8 0.2 0.051 12.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 OWF51147.1 - 0.042 13.9 0.3 0.073 13.1 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OWF51147.1 - 0.075 13.6 1.9 0.12 12.9 0.4 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF51147.1 - 0.11 11.5 1.2 0.19 10.7 1.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A CUB PF00431.20 OWF51148.1 - 4.7e-14 52.7 0.0 7.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF5518 PF17647.1 OWF51148.1 - 0.0052 16.9 0.0 0.0084 16.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5518) FH2 PF02181.23 OWF51149.1 - 3.7e-78 263.3 2.4 3.7e-78 263.3 2.4 1.8 1 1 1 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OWF51149.1 - 4.7e-27 94.9 1.3 4.7e-27 94.9 1.3 2.8 2 1 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OWF51149.1 - 7.9e-12 45.1 1.4 1.5e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Spectrin PF00435.21 OWF51149.1 - 0.0076 16.7 1.8 0.039 14.4 1.8 2.3 1 1 0 1 1 1 1 Spectrin repeat DUF1351 PF07083.11 OWF51149.1 - 0.019 14.7 8.2 0.04 13.7 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) HsbA PF12296.8 OWF51149.1 - 0.04 14.4 0.4 8.1 6.9 0.1 3.4 3 1 0 3 3 3 0 Hydrophobic surface binding protein A NPV_P10 PF05531.12 OWF51149.1 - 0.044 14.3 2.9 0.084 13.4 0.8 2.6 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Myb_DNA-bind_5 PF13873.6 OWF51149.1 - 0.069 13.2 2.5 0.39 10.8 0.0 2.9 3 0 0 3 3 2 0 Myb/SANT-like DNA-binding domain DASH_Spc34 PF08657.10 OWF51149.1 - 0.21 11.4 12.0 9.3 6.0 9.1 3.3 2 1 1 3 3 3 0 DASH complex subunit Spc34 DUF948 PF06103.11 OWF51149.1 - 0.21 11.9 4.1 0.2 11.9 0.5 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3886 PF13025.6 OWF51149.1 - 0.28 11.4 6.0 1.3 9.3 6.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) RPW8 PF05659.11 OWF51149.1 - 0.86 9.3 6.8 2.6 7.7 6.0 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 P4Ha_N PF08336.11 OWF51149.1 - 2.8 7.9 6.5 3.7 7.6 0.7 2.8 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ApoLp-III PF07464.11 OWF51149.1 - 3.5 7.7 9.5 4.3 7.4 1.0 2.6 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Syntaxin-6_N PF09177.11 OWF51149.1 - 3.8 8.1 7.8 45 4.7 7.8 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal KxDL PF10241.9 OWF51149.1 - 7.1 7.0 7.8 0.92 9.8 0.7 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF2203 PF09969.9 OWF51149.1 - 8.8 7.1 8.7 37 5.1 1.9 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Galactosyl_T PF01762.21 OWF51150.1 - 2.4e-41 141.7 0.5 3.6e-41 141.1 0.5 1.2 1 0 0 1 1 1 1 Galactosyltransferase CotE PF10628.9 OWF51150.1 - 0.051 13.2 1.1 0.09 12.4 1.1 1.3 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) Galactosyl_T PF01762.21 OWF51151.1 - 7.7e-40 136.8 0.5 1.2e-39 136.2 0.5 1.2 1 0 0 1 1 1 1 Galactosyltransferase Abhydrolase_6 PF12697.7 OWF51152.1 - 3.7e-27 96.4 0.1 2.7e-26 93.5 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF51152.1 - 7.1e-12 45.5 0.0 1.3e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF51152.1 - 2.4e-07 30.3 0.0 4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OWF51152.1 - 0.0003 20.6 0.2 0.00069 19.4 0.1 1.7 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 OWF51152.1 - 0.0043 17.2 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 OWF51152.1 - 0.007 16.2 0.0 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_3 PF07859.13 OWF51152.1 - 0.011 15.6 0.8 0.095 12.5 0.8 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OWF51152.1 - 0.018 14.8 0.1 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase C2 PF00168.30 OWF51153.1 - 3.6e-16 59.3 0.0 1e-05 25.7 0.1 6.0 6 1 0 6 6 6 4 C2 domain DOCK-C2 PF14429.6 OWF51153.1 - 0.0078 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Beta-lactamase PF00144.24 OWF51154.1 - 8.7e-52 176.4 0.0 1.2e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 OWF51154.1 - 0.00053 20.4 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) RhoGEF PF00621.20 OWF51155.1 - 2.1e-35 122.6 2.2 4.3e-35 121.6 2.2 1.6 1 0 0 1 1 1 1 RhoGEF domain T3SS_NleG PF06416.12 OWF51155.1 - 0.011 15.6 0.3 0.027 14.4 0.3 1.6 1 0 0 1 1 1 0 Effector protein NleG VWA PF00092.28 OWF51156.1 - 4.4e-33 115.0 5.7 9.1e-33 113.9 5.7 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF51156.1 - 7e-18 65.2 1.6 1.6e-17 64.0 1.6 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF51156.1 - 8.9e-07 29.0 0.2 1.3e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF51156.1 - 5.6e-05 22.6 2.4 8.5e-05 22.0 2.4 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CD99L2 PF12301.8 OWF51156.1 - 0.0028 18.0 7.1 0.3 11.4 3.5 2.4 2 1 0 2 2 2 2 CD99 antigen like protein 2 TrbC PF04956.13 OWF51156.1 - 1.8 8.8 6.8 18 5.6 0.3 3.0 3 0 0 3 3 3 0 TrbC/VIRB2 family VWA PF00092.28 OWF51158.1 - 2.9e-25 89.5 0.1 4.7e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF51158.1 - 7.9e-13 49.0 0.1 1.7e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF51158.1 - 2.6e-06 27.5 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Gp58 PF07902.11 OWF51158.1 - 0.0046 15.3 0.0 0.012 14.0 0.0 1.6 1 1 0 1 1 1 1 gp58-like protein VWA_CoxE PF05762.14 OWF51158.1 - 0.018 14.5 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Mur_ligase_C PF02875.21 OWF51158.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Gram_pos_anchor PF00746.21 OWF51158.1 - 0.23 11.4 11.3 8.7 6.4 0.2 5.8 6 0 0 6 6 6 0 LPXTG cell wall anchor motif SF-assemblin PF06705.11 OWF51158.1 - 0.24 10.7 1.0 6.5 6.0 0.1 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF5409 PF17421.2 OWF51159.1 - 0.04 14.6 5.6 1.3 9.8 0.0 3.6 1 1 3 4 4 4 0 Family of unknown function (DUF5409) Aldedh PF00171.22 OWF51159.1 - 9.1 4.7 7.5 14 4.0 0.3 3.0 2 1 1 3 3 3 0 Aldehyde dehydrogenase family VWA PF00092.28 OWF51160.1 - 1.1e-44 152.7 10.7 4.6e-22 79.1 1.5 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OWF51160.1 - 1.6e-05 24.9 0.7 0.049 13.6 0.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Sec23_trunk PF04811.15 OWF51160.1 - 0.00013 21.6 6.5 0.014 15.0 0.6 2.7 2 1 0 2 2 2 2 Sec23/Sec24 trunk domain RBR PF17208.3 OWF51160.1 - 1.8 9.3 5.7 5.5 7.8 5.7 1.8 1 0 0 1 1 1 0 RNA binding Region TMEM154 PF15102.6 OWF51160.1 - 4.3 7.2 0.0 4.3 7.2 0.0 3.8 3 1 1 4 4 4 0 TMEM154 protein family RNase_PH PF01138.21 OWF51161.1 - 1.3e-16 61.3 0.0 2.7e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OWF51161.1 - 1.3e-10 41.2 0.1 1.3e-10 41.2 0.1 2.3 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 ThiS-like PF14453.6 OWF51161.1 - 0.064 13.3 1.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 ThiS-like ubiquitin PhoLip_ATPase_C PF16212.5 OWF51162.1 - 1.3e-87 293.7 23.9 1.3e-87 293.7 23.9 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OWF51162.1 - 4.4e-25 87.2 5.1 4.4e-25 87.2 5.1 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OWF51162.1 - 6.6e-14 51.8 0.0 7.9e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OWF51162.1 - 7.1e-12 46.1 2.1 7.4e-07 29.7 1.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OWF51162.1 - 3.2e-08 33.3 0.0 1.8e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OWF51162.1 - 0.011 15.5 0.1 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FtsL PF04999.13 OWF51162.1 - 0.076 13.0 1.5 9 6.4 0.0 2.8 2 0 0 2 2 2 0 Cell division protein FtsL HMG_box_2 PF09011.10 OWF51163.1 - 4e-32 110.6 11.6 2e-21 76.4 4.5 2.1 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 OWF51163.1 - 4.1e-31 107.2 6.9 1.5e-15 57.3 2.5 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box YABBY PF04690.13 OWF51163.1 - 0.0036 17.9 2.1 0.0047 17.5 2.1 1.2 1 0 0 1 1 1 1 YABBY protein Use1 PF09753.9 OWF51163.1 - 0.013 15.2 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ccdc124 PF06244.12 OWF51163.1 - 0.043 14.4 2.5 0.12 13.0 2.5 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 OWF51163.1 - 1.4 9.0 7.1 4 7.5 3.0 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 zf-SAP30 PF13866.6 OWF51164.1 - 1.4e-39 134.0 7.5 3.7e-39 132.7 7.5 1.7 1 0 0 1 1 1 1 SAP30 zinc-finger SAP30_Sin3_bdg PF13867.6 OWF51164.1 - 2.6e-21 75.7 0.3 2.6e-21 75.7 0.3 2.0 3 0 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF5496 PF17600.2 OWF51164.1 - 0.26 11.3 1.7 4.6 7.4 0.5 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5496) JAB PF01398.21 OWF51165.1 - 6.6e-26 90.6 0.1 1.2e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OWF51165.1 - 5.9e-24 84.7 1.0 9.4e-24 84.0 1.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function NFRKB_winged PF14465.6 OWF51166.1 - 6.3e-37 125.9 1.4 2.1e-36 124.2 1.0 2.2 2 0 0 2 2 2 1 NFRKB Winged Helix-like 7tm_1 PF00001.21 OWF51167.1 - 1e-24 87.3 23.8 1.5e-24 86.8 23.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF51167.1 - 1.5e-05 24.7 27.4 1.8e-05 24.5 26.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx VWA PF00092.28 OWF51168.1 - 2.9e-06 27.6 0.9 1e-05 25.9 0.1 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF51168.1 - 0.00014 22.4 0.0 0.00056 20.5 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF51168.1 - 0.069 12.5 0.1 0.25 10.7 0.1 2.0 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein QVR PF17064.5 OWF51169.1 - 2.4e-08 34.1 11.4 3e-08 33.8 11.4 1.1 1 0 0 1 1 1 1 Sleepless protein Activin_recp PF01064.23 OWF51169.1 - 0.44 11.7 16.0 0.62 11.2 16.0 1.2 1 0 0 1 1 1 0 Activin types I and II receptor domain Neur_chan_LBD PF02931.23 OWF51171.1 - 4.3e-35 121.1 0.7 6.1e-35 120.6 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51171.1 - 4.5e-32 112.0 1.8 3.9e-27 95.9 3.2 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region MNHE PF01899.16 OWF51171.1 - 0.0032 17.2 1.6 0.0052 16.5 1.6 1.3 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit Methyltransf_FA PF12248.8 OWF51172.1 - 0.0031 17.8 15.1 6.7 7.1 0.1 7.4 4 2 6 11 11 11 6 Farnesoic acid 0-methyl transferase fn3 PF00041.21 OWF51173.1 - 1e-07 32.2 3.0 0.11 12.8 0.3 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.6 OWF51173.1 - 0.00011 22.5 0.1 0.031 14.6 0.0 3.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 OWF51173.1 - 0.00058 20.0 1.4 0.53 10.5 0.1 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 OWF51173.1 - 0.02 15.5 1.4 0.42 11.2 0.1 3.7 3 0 0 3 3 3 0 Immunoglobulin domain Interfer-bind PF09294.10 OWF51173.1 - 0.11 12.8 0.4 1.1 9.6 0.1 2.8 2 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III V-set PF07686.17 OWF51173.1 - 0.94 9.7 6.3 3.2 8.0 0.3 4.4 4 1 1 5 5 5 0 Immunoglobulin V-set domain p450 PF00067.22 OWF51174.1 - 1.2e-91 307.8 0.0 1.5e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF51175.1 - 3.7e-117 391.9 0.0 4.2e-117 391.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tma16 PF11176.8 OWF51175.1 - 0.23 11.3 0.1 0.37 10.7 0.1 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 NADH_dh_m_C1 PF15088.6 OWF51175.1 - 0.27 10.9 2.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial p450 PF00067.22 OWF51176.1 - 6.7e-113 377.9 0.0 8.3e-113 377.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tma16 PF11176.8 OWF51176.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 LAX PF15681.5 OWF51176.1 - 0.3 9.9 0.1 0.48 9.2 0.1 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X DEAD PF00270.29 OWF51177.1 - 2.2e-19 69.9 0.1 5.3e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF51177.1 - 3.5e-13 49.9 0.0 3.5e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OWF51177.1 - 8.4e-11 42.4 1.2 3.5e-10 40.5 1.2 2.2 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 OWF51177.1 - 2.2e-06 27.8 0.8 6.3e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_transf_54 PF04666.13 OWF51178.1 - 1.9e-119 397.9 0.0 2.8e-119 397.3 0.0 1.3 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Ank_2 PF12796.7 OWF51179.1 - 1.9e-31 108.5 2.3 9.8e-12 45.3 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF51179.1 - 1.2e-26 92.4 7.5 5.8e-10 39.2 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF51179.1 - 3.7e-22 76.0 5.2 0.00071 19.8 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OWF51179.1 - 6.9e-21 74.4 6.4 2e-09 37.8 0.4 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF51179.1 - 1e-19 70.0 17.1 0.00035 20.9 0.2 7.1 7 0 0 7 7 7 6 Ankyrin repeat TolA PF06519.11 OWF51179.1 - 0.21 11.8 0.3 1.2 9.4 0.2 2.1 1 1 1 2 2 2 0 TolA C-terminal MIEAP PF16026.5 OWF51180.1 - 7.4e-26 91.6 2.5 5.8e-25 88.7 0.0 2.2 2 0 0 2 2 2 1 Mitochondria-eating protein ATG16 PF08614.11 OWF51180.1 - 0.0064 16.7 11.8 0.012 15.9 11.8 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 OWF51180.1 - 0.008 16.4 10.7 0.016 15.4 10.7 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 OWF51180.1 - 0.02 14.4 13.4 0.035 13.6 13.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 OWF51180.1 - 0.17 11.9 3.5 0.35 10.9 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 OWF51180.1 - 0.23 11.5 13.1 0.41 10.7 13.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 OWF51180.1 - 0.34 10.2 20.4 0.059 12.7 16.7 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OWF51180.1 - 0.38 9.6 12.8 0.58 9.0 12.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TipAS PF07739.13 OWF51180.1 - 0.41 11.2 3.1 0.82 10.2 2.8 1.6 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain KxDL PF10241.9 OWF51180.1 - 0.54 10.6 10.1 1.5 9.2 10.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein PRKG1_interact PF15898.5 OWF51180.1 - 0.68 10.9 16.5 1.7 9.6 6.0 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 OWF51180.1 - 0.68 10.1 12.1 8.6 6.5 6.7 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 OWF51180.1 - 0.77 10.2 14.2 26 5.4 14.1 2.7 1 1 0 1 1 1 0 Cell division protein ZapB V_ATPase_I PF01496.19 OWF51180.1 - 1 7.2 4.3 1.4 6.8 4.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 OWF51180.1 - 2.2 8.1 15.5 2.8 7.8 7.3 2.5 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 OWF51180.1 - 2.8 8.3 9.7 1.1 9.6 6.3 2.1 2 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 OWF51180.1 - 4.3 7.5 16.3 7.6 6.7 15.3 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fungal_TACC PF12709.7 OWF51180.1 - 5 7.7 10.3 2.3 8.7 6.1 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_Maf PF03131.17 OWF51180.1 - 6 7.5 18.9 1.8 9.1 11.3 2.5 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF4407 PF14362.6 OWF51180.1 - 7.1 5.9 9.0 12 5.2 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4349 PF14257.6 OWF51180.1 - 8.5 5.8 6.7 4.8 6.6 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) GIT_CC PF16559.5 OWF51180.1 - 8.7 6.3 13.0 20 5.1 7.0 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UBN_AB PF14075.6 OWF51181.1 - 1.8e-72 243.5 10.8 1.8e-72 243.5 10.8 3.4 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 OWF51181.1 - 5.1e-19 68.0 0.0 1.4e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain PID PF00640.23 OWF51182.1 - 3.8e-26 91.8 0.0 9.6e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.26 OWF51182.1 - 6.4e-05 22.9 0.7 6.4e-05 22.9 0.7 2.0 2 0 0 2 2 2 1 WW domain PTB PF08416.13 OWF51182.1 - 0.00013 22.1 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Methyltr_RsmB-F PF01189.17 OWF51183.1 - 4.1e-06 26.6 0.0 1.1e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Carb_anhydrase PF00194.21 OWF51184.1 - 1.6e-67 227.7 0.0 1.9e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase SMBP PF16785.5 OWF51185.1 - 1.5e-07 31.6 0.0 0.011 16.0 0.0 3.5 1 1 1 2 2 2 2 Small metal-binding protein RPW8 PF05659.11 OWF51185.1 - 7.7e-05 22.4 0.0 18 5.0 0.0 4.5 1 1 3 4 4 4 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3342 PF11822.8 OWF51185.1 - 0.00012 22.2 6.9 15 5.8 6.9 4.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) FH2 PF02181.23 OWF51185.1 - 0.096 11.8 1.6 0.45 9.6 1.2 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain FSA_C PF10479.9 OWF51185.1 - 1.3 7.1 5.2 39 2.2 0.1 3.9 1 1 2 4 4 4 0 Fragile site-associated protein C-terminus Sad1_UNC PF07738.13 OWF51185.1 - 2.3 8.2 11.4 1.1e+02 2.8 0.4 4.3 1 1 1 2 2 2 0 Sad1 / UNC-like C-terminal adh_short PF00106.25 OWF51186.1 - 1.1e-33 116.4 0.0 1.1e-26 93.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF51186.1 - 2.5e-24 86.1 0.0 2e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF51186.1 - 6.4e-09 36.0 0.1 9.2e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF51186.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 OWF51186.1 - 0.09 13.3 0.0 0.23 12.0 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 OWF51187.1 - 1.8e-29 102.6 0.0 1.1e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF51187.1 - 2.2e-22 79.8 0.0 6.6e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF51187.1 - 6.4e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain HATPase_c_5 PF14501.6 OWF51187.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 GHKL domain HATPase_c PF02518.26 OWF51187.1 - 0.13 12.8 0.0 0.37 11.3 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 OWF51188.1 - 7.5e-31 107.1 0.0 2e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF51188.1 - 1e-22 80.9 0.0 3.9e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF51188.1 - 1.5e-05 25.0 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF51188.1 - 2.1e-05 24.1 0.0 0.00066 19.2 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OWF51188.1 - 0.0059 15.8 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Fe-S_biosyn PF01521.20 OWF51189.1 - 0.004 17.3 0.3 2.9 8.1 0.0 3.3 1 1 1 3 3 3 2 Iron-sulphur cluster biosynthesis Cyclin_N PF00134.23 OWF51189.1 - 1 9.1 10.8 25 4.6 0.7 4.3 1 1 4 5 5 5 0 Cyclin, N-terminal domain Zip PF02535.22 OWF51190.1 - 0.63 9.2 3.4 0.79 8.9 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OWF51190.1 - 9.8 4.8 17.4 12 4.6 17.4 1.1 1 0 0 1 1 1 0 Presenilin VWA PF00092.28 OWF51191.1 - 8.8e-65 218.2 4.3 1.6e-31 109.9 0.3 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF51191.1 - 8.5e-29 100.4 0.6 5.9e-13 49.4 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF51191.1 - 4.6e-12 45.8 0.2 7.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA_3 PF13768.6 OWF51191.1 - 2.8e-11 43.6 0.0 0.00028 20.8 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF2201 PF09967.9 OWF51191.1 - 2.9e-07 30.6 0.1 0.041 14.0 0.0 2.6 2 0 0 2 2 2 2 VWA-like domain (DUF2201) Sec23_trunk PF04811.15 OWF51191.1 - 0.0098 15.5 3.1 2.3 7.7 0.2 2.4 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain DUF2140 PF09911.9 OWF51191.1 - 0.027 14.0 0.1 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) PrpR_N PF06506.11 OWF51191.1 - 0.066 12.8 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator AFOR_N PF02730.15 OWF51191.1 - 0.11 12.3 0.2 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain BDM PF10684.9 OWF51191.1 - 0.26 11.7 0.8 33 4.9 0.1 2.5 2 0 0 2 2 2 0 Putative biofilm-dependent modulation protein HCV_NS4a PF01006.20 OWF51191.1 - 0.87 9.4 2.8 2.2 8.1 2.8 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF3364 PF11844.8 OWF51192.1 - 1.1 9.5 10.5 1.2e+02 3.0 0.0 6.0 6 0 0 6 6 6 0 Domain of unknown function (DUF3364) Neur_chan_LBD PF02931.23 OWF51193.1 - 1.2e-39 136.0 0.4 1.7e-39 135.5 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51193.1 - 3.5e-29 102.5 6.3 3.8e-27 95.9 1.8 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Anth_Ig PF05587.13 OWF51194.1 - 0.0078 16.5 9.8 1.6 9.1 0.3 3.9 1 1 4 5 5 5 3 Anthrax receptor extracellular domain Crust_neurohorm PF01147.17 OWF51194.1 - 0.072 12.9 13.9 13 5.7 0.6 5.4 1 1 5 6 6 6 0 Crustacean CHH/MIH/GIH neurohormone family OFCC1 PF15680.5 OWF51194.1 - 5.1 7.7 14.6 14 6.3 2.9 3.3 1 1 2 3 3 3 0 Orofacial cleft 1 candidate gene 1 protein DUF4573 PF15140.6 OWF51195.1 - 3.9e-09 36.5 0.0 2.4e-05 24.2 0.0 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) HTH_1 PF00126.27 OWF51195.1 - 0.0075 16.2 2.2 25 4.9 0.0 5.2 6 0 0 6 6 6 1 Bacterial regulatory helix-turn-helix protein, lysR family UPF0147 PF03685.13 OWF51195.1 - 0.016 15.3 3.9 0.15 12.1 0.4 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0147) Phage_Gp19 PF09355.10 OWF51195.1 - 2.7 8.4 7.3 0.93 9.9 2.3 2.1 1 1 1 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Mgm101p PF06420.12 OWF51196.1 - 0.034 13.7 9.1 1.4 8.4 0.4 3.3 1 1 1 3 3 3 0 Mitochondrial genome maintenance MGM101 Anth_Ig PF05587.13 OWF51196.1 - 0.12 12.7 12.7 9.3 6.6 0.1 4.5 1 1 4 5 5 5 0 Anthrax receptor extracellular domain Crust_neurohorm PF01147.17 OWF51196.1 - 0.25 11.2 23.8 1.5 8.7 0.3 5.1 1 1 3 5 5 5 0 Crustacean CHH/MIH/GIH neurohormone family DUF4458 PF14660.6 OWF51196.1 - 0.99 9.7 8.1 1.5 9.0 1.0 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4458) OFCC1 PF15680.5 OWF51196.1 - 5.3 7.7 10.9 4 8.0 2.7 3.3 1 1 3 4 4 4 0 Orofacial cleft 1 candidate gene 1 protein Neur_chan_LBD PF02931.23 OWF51197.1 - 7e-41 140.0 2.7 9.8e-41 139.6 2.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51197.1 - 7.6e-29 101.4 4.9 3.9e-24 86.0 4.0 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region MIEAP PF16026.5 OWF51198.1 - 1.7e-30 106.8 1.0 3.2e-29 102.6 0.0 2.3 2 0 0 2 2 2 1 Mitochondria-eating protein ATG16 PF08614.11 OWF51198.1 - 0.044 14.0 17.2 0.14 12.3 17.1 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 OWF51198.1 - 0.42 10.2 18.4 0.94 9.0 18.4 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Golgin_A5 PF09787.9 OWF51198.1 - 0.55 9.7 21.0 2 7.8 21.0 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4407 PF14362.6 OWF51198.1 - 0.67 9.2 11.0 1 8.6 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 OWF51198.1 - 1.7 8.7 27.1 4.1 7.4 27.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 OWF51198.1 - 1.8 9.1 27.5 6.9 7.2 27.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 OWF51198.1 - 2.3 7.7 9.0 3.8 7.0 9.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit KLRAQ PF10205.9 OWF51198.1 - 3.2 8.0 18.5 1.7 8.9 4.3 3.4 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Spore_III_AB PF09548.10 OWF51198.1 - 4.4 7.4 11.3 0.13 12.4 3.6 2.4 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) FapA PF03961.13 OWF51198.1 - 5.8 5.4 10.1 13 4.3 10.1 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A CCDC-167 PF15188.6 OWF51198.1 - 6.4 7.2 20.8 1.2 9.5 14.4 2.9 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.19 OWF51198.1 - 7.3 4.4 10.9 10 3.9 10.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MIEAP PF16026.5 OWF51199.1 - 3.9e-31 108.8 1.5 5.3e-30 105.1 0.0 2.6 2 0 0 2 2 2 1 Mitochondria-eating protein ADIP PF11559.8 OWF51199.1 - 0.021 14.9 20.0 0.46 10.6 17.0 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 OWF51199.1 - 0.083 10.8 8.0 0.17 9.8 8.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 OWF51199.1 - 0.14 11.4 5.9 0.22 10.8 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SYCE1 PF15233.6 OWF51199.1 - 0.75 9.8 19.7 0.44 10.6 17.1 1.8 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Exonuc_VII_L PF02601.15 OWF51199.1 - 1.3 8.5 7.7 0.16 11.5 3.3 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF812 PF05667.11 OWF51199.1 - 1.5 7.6 19.7 0.09 11.6 13.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) FapA PF03961.13 OWF51199.1 - 4.3 5.8 10.9 7.8 5.0 10.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ERM PF00769.19 OWF51199.1 - 4.9 6.9 22.8 0.27 11.0 15.7 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family rve PF00665.26 OWF51202.1 - 0.0099 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Rap1_C PF11626.8 OWF51202.1 - 0.016 15.3 0.0 0.041 14.0 0.0 1.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MIEAP PF16026.5 OWF51203.1 - 1.8e-34 119.7 0.0 1.8e-34 119.7 0.0 2.4 3 0 0 3 3 3 1 Mitochondria-eating protein DUF812 PF05667.11 OWF51203.1 - 0.0063 15.5 10.6 0.013 14.5 10.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MatP_C PF17414.2 OWF51203.1 - 0.013 15.7 1.6 0.038 14.2 1.6 1.8 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain SYCE1 PF15233.6 OWF51203.1 - 0.12 12.5 16.7 0.26 11.3 16.7 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 V_ATPase_I PF01496.19 OWF51203.1 - 0.14 10.0 5.6 0.25 9.2 5.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1843 PF08898.10 OWF51203.1 - 1.3 9.6 5.0 9.3 6.8 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) DUF4404 PF14357.6 OWF51203.1 - 5 7.8 8.7 18 6.1 8.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) MIEAP PF16026.5 OWF51204.1 - 8.7e-07 29.4 0.0 8.7e-07 29.4 0.0 2.3 2 1 0 2 2 2 1 Mitochondria-eating protein Herpes_UL6 PF01763.16 OWF51204.1 - 0.051 12.1 7.0 0.072 11.6 7.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like FapA PF03961.13 OWF51204.1 - 0.14 10.8 11.8 0.19 10.3 11.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A tRNA-synt_1d PF00750.19 OWF51204.1 - 0.57 9.1 6.1 0.41 9.5 3.4 1.9 1 1 1 2 2 2 0 tRNA synthetases class I (R) DUF4407 PF14362.6 OWF51204.1 - 1.3 8.3 11.8 2 7.7 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 OWF51204.1 - 2.4 7.4 12.5 4 6.7 11.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HSP70 PF00012.20 OWF51205.1 - 1.4e-13 49.9 0.6 3.3e-13 48.7 0.6 1.6 1 1 0 1 1 1 1 Hsp70 protein DDR PF08841.10 OWF51205.1 - 0.008 15.2 0.6 0.02 13.9 0.6 1.7 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain MreB_Mbl PF06723.13 OWF51205.1 - 0.028 13.2 0.0 0.76 8.5 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 OWF51206.1 - 4e-06 25.3 0.0 1.4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 OWF51206.1 - 0.046 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 OWF51207.1 - 5.5e-11 41.4 0.0 2.7e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF51207.1 - 0.0038 16.1 0.4 2.4 6.9 0.1 2.8 2 1 0 2 2 2 2 MreB/Mbl protein RNA_pol_L PF01193.24 OWF51207.1 - 0.048 13.1 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DDR PF08841.10 OWF51207.1 - 0.11 11.5 0.5 1.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 OWF51207.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MIEAP PF16026.5 OWF51208.1 - 1.1e-40 140.0 3.3 1.1e-40 140.0 0.0 2.4 3 1 0 3 3 3 1 Mitochondria-eating protein TipAS PF07739.13 OWF51208.1 - 0.25 11.9 2.9 0.4 11.2 0.3 2.6 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain MIEAP PF16026.5 OWF51209.1 - 2.9e-32 112.5 10.1 1.3e-23 84.3 0.0 2.8 3 0 0 3 3 3 2 Mitochondria-eating protein CcdA PF07362.12 OWF51209.1 - 5.1 7.6 6.2 2.6 8.5 1.5 2.9 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA MIEAP PF16026.5 OWF51210.1 - 1.8e-33 116.4 0.2 1.8e-33 116.4 0.2 1.8 2 0 0 2 2 2 1 Mitochondria-eating protein DUF1779 PF08680.10 OWF51210.1 - 0.049 13.8 5.6 0.062 13.5 3.2 2.0 1 1 1 2 2 2 0 TATA-box binding PARP PF00644.20 OWF51211.1 - 2e-21 76.5 0.2 8.1e-21 74.5 0.0 2.2 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Macro PF01661.21 OWF51211.1 - 0.00043 20.3 0.0 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 Macro domain Pox_H7 PF04787.12 OWF51211.1 - 0.022 15.3 0.2 0.07 13.6 0.0 1.9 2 0 0 2 2 2 0 Late protein H7 DUF3990 PF13151.6 OWF51211.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Exotox-A_cataly PF09009.10 OWF51211.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic I-set PF07679.16 OWF51212.1 - 6.5e-152 494.1 0.0 3e-21 75.3 0.0 10.6 11 0 0 11 11 10 8 Immunoglobulin I-set domain fn3 PF00041.21 OWF51212.1 - 1.1e-148 484.0 44.3 2.1e-11 44.0 0.0 18.8 19 0 0 19 19 19 18 Fibronectin type III domain Pkinase PF00069.25 OWF51212.1 - 8.5e-101 336.7 0.0 2.3e-55 187.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 OWF51212.1 - 1.2e-100 330.2 0.6 3.8e-12 46.6 0.0 9.8 9 0 0 9 9 9 8 Immunoglobulin domain Ig_2 PF13895.6 OWF51212.1 - 3.2e-60 200.4 4.4 6e-08 32.9 0.0 8.9 8 0 0 8 8 8 8 Immunoglobulin domain Pkinase_Tyr PF07714.17 OWF51212.1 - 1.4e-50 172.0 0.0 4.6e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase ig PF00047.25 OWF51212.1 - 1.6e-48 162.8 7.4 3e-07 30.5 0.2 8.6 8 0 0 8 8 8 8 Immunoglobulin domain V-set PF07686.17 OWF51212.1 - 1.6e-24 86.1 9.0 0.0039 17.3 0.3 11.0 9 2 0 9 9 8 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 OWF51212.1 - 8.5e-22 77.5 12.8 0.33 11.6 0.1 16.5 15 2 0 15 15 15 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 OWF51212.1 - 2.3e-14 53.2 1.1 1.8 8.7 0.0 7.7 7 0 0 7 7 7 3 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.6 OWF51212.1 - 1.7e-10 40.7 0.0 3.6e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OWF51212.1 - 8.6e-07 28.5 1.3 3.6e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family C1-set PF07654.15 OWF51212.1 - 1.5e-06 28.5 0.9 0.83 10.1 0.0 6.7 6 0 0 6 6 6 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 OWF51212.1 - 4.2e-06 26.2 3.1 3 7.5 0.1 6.6 7 0 0 7 7 7 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF51212.1 - 4.5e-05 23.4 0.0 2 8.5 0.0 5.5 6 0 0 6 6 5 1 C17orf99 Ig domain Ig_5 PF16681.5 OWF51212.1 - 9.7e-05 22.7 7.0 0.18 12.2 0.0 5.6 7 0 0 7 7 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain fn3_2 PF16893.5 OWF51212.1 - 0.0002 21.5 0.0 3.6 7.8 0.0 6.5 7 0 0 7 7 7 1 Fibronectin type III domain DUF5581 PF17744.1 OWF51212.1 - 0.035 13.5 0.0 32 3.7 0.0 4.4 6 0 0 6 6 6 0 Family of unknown function (DUF5581) PKD_3 PF16820.5 OWF51212.1 - 0.057 13.2 0.0 1.7 8.4 0.0 3.1 2 0 0 2 2 2 0 PKD-like domain I-set PF07679.16 OWF51213.1 - 2e-17 63.0 0.0 5.9e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF51213.1 - 3.5e-11 43.6 0.1 2.1e-10 41.0 0.1 2.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 OWF51213.1 - 1.5e-08 34.6 0.2 4.6e-08 33.1 0.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF51213.1 - 5.1e-05 23.5 0.1 0.0001 22.6 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 OWF51213.1 - 0.021 15.0 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF51213.1 - 0.079 13.2 2.9 0.15 12.3 0.1 2.9 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain zf-B_box PF00643.24 OWF51214.1 - 5.2e-14 52.1 24.4 3.7e-09 36.6 9.4 2.7 2 0 0 2 2 2 2 B-box zinc finger NHL PF01436.21 OWF51214.1 - 0.013 15.5 0.3 3.5 7.8 0.1 3.3 2 0 0 2 2 2 0 NHL repeat Reg_prop PF07494.11 OWF51214.1 - 0.025 14.8 0.3 0.95 9.9 0.0 3.6 4 0 0 4 4 4 0 Two component regulator propeller zf-UBP PF02148.19 OWF51214.1 - 0.066 13.6 14.7 0.19 12.0 14.4 2.0 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein V-SNARE PF05008.15 OWF51214.1 - 0.23 11.9 4.1 0.23 11.9 0.7 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Lectin_C PF00059.21 OWF51215.1 - 1.6e-13 51.3 0.0 2.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF51215.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF51216.1 - 2.4e-11 44.3 0.0 3.5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF51216.1 - 0.074 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Spectrin PF00435.21 OWF51217.1 - 1.1e-09 38.7 2.4 7.2e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 Spectrin repeat RNase_T PF00929.24 OWF51218.1 - 9.8e-07 29.5 0.0 1.3e-05 25.9 0.0 2.4 2 0 0 2 2 2 1 Exonuclease RNase_H_2 PF13482.6 OWF51218.1 - 0.00092 19.2 0.0 0.027 14.5 0.0 2.7 3 0 0 3 3 3 1 RNase_H superfamily DEAD PF00270.29 OWF51219.1 - 1e-49 168.7 0.0 1.2e-48 165.2 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF51219.1 - 2.8e-22 79.1 0.0 1.3e-21 77.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OWF51219.1 - 1.9e-15 56.8 0.0 4.9e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OWF51219.1 - 4.4e-08 33.3 1.7 7.5e-08 32.6 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4691 PF15762.5 OWF51219.1 - 0.18 11.9 4.5 0.76 9.9 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4691) UPF0449 PF15136.6 OWF51220.1 - 2.9e-19 69.4 0.3 4.1e-19 68.9 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 DivIVA PF05103.13 OWF51220.1 - 0.011 15.9 0.3 0.015 15.3 0.3 1.3 1 0 0 1 1 1 0 DivIVA protein mCpol PF18182.1 OWF51220.1 - 0.011 16.1 0.9 0.14 12.5 0.1 2.1 1 1 1 2 2 2 0 minimal CRISPR polymerase domain GerE PF00196.19 OWF51221.1 - 0.00049 19.6 8.5 0.54 9.9 0.3 4.4 1 1 5 6 6 6 2 Bacterial regulatory proteins, luxR family Tcp10_C PF07202.13 OWF51221.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 T-complex protein 10 C-terminus DUF2689 PF10894.8 OWF51221.1 - 0.0084 15.9 39.6 1.2 9.0 2.7 7.8 1 1 7 8 8 8 6 Protein of unknown function (DUF2689) DUF1411 PF07199.11 OWF51221.1 - 0.059 13.0 13.2 0.27 10.9 1.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1411) DUF3898 PF13037.6 OWF51221.1 - 0.067 13.3 0.0 28 4.9 0.0 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF3898) Crisp PF08562.10 OWF51221.1 - 0.11 13.1 75.5 0.17 12.5 17.2 4.9 1 1 3 4 4 4 0 Crisp GerE PF00196.19 OWF51222.1 - 0.0036 16.8 6.9 0.46 10.1 0.4 3.7 1 1 3 4 4 4 2 Bacterial regulatory proteins, luxR family DUF2689 PF10894.8 OWF51222.1 - 0.011 15.5 33.4 1.1 9.1 3.0 6.7 1 1 7 8 8 8 0 Protein of unknown function (DUF2689) DUF3898 PF13037.6 OWF51222.1 - 0.084 13.0 0.0 22 5.2 0.0 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF3898) Tcp10_C PF07202.13 OWF51222.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 T-complex protein 10 C-terminus Crisp PF08562.10 OWF51222.1 - 0.22 12.1 68.2 0.14 12.8 17.3 4.3 1 1 3 4 4 4 0 Crisp DUF1411 PF07199.11 OWF51222.1 - 0.23 11.1 11.1 0.38 10.4 2.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1411) Vanabin-2 PF11437.8 OWF51222.1 - 2 8.6 64.2 35 4.6 16.7 3.2 1 1 2 3 3 3 0 Vanadium-binding protein 2 DUF2357 PF09823.9 OWF51222.1 - 5.6 6.2 5.0 73 2.5 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF2357) Stn1_C PF12659.7 OWF51222.1 - 7.5 6.5 10.2 5.9 6.9 3.4 2.2 1 1 1 2 2 2 0 Telomere capping C-terminal wHTH Ank_4 PF13637.6 OWF51223.1 - 3.2e-06 27.6 0.0 1.6e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF51223.1 - 4.3e-05 23.7 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF51223.1 - 0.00013 22.5 0.0 0.00032 21.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF51223.1 - 0.0011 19.2 0.0 0.76 10.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OWF51223.1 - 0.0029 18.0 0.0 2.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Fip1 PF05182.13 OWF51223.1 - 0.021 14.3 1.2 0.021 14.3 1.2 2.4 2 0 0 2 2 2 0 Fip1 motif Adeno_IVa2 PF02456.15 OWF51223.1 - 0.049 12.4 0.1 0.088 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2072 PF09845.9 OWF51223.1 - 0.093 13.0 5.5 0.28 11.4 5.5 1.8 1 0 0 1 1 1 0 Zn-ribbon containing protein Tup_N PF08581.10 OWF51223.1 - 0.18 12.2 9.5 0.27 11.5 2.4 3.3 1 1 1 3 3 3 0 Tup N-terminal DUF883 PF05957.13 OWF51223.1 - 2.8 8.6 4.6 8.4 7.1 4.6 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF87 PF01935.17 OWF51223.1 - 8.3 6.4 8.3 13 5.8 7.4 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain PAN_1 PF00024.26 OWF51224.1 - 0.0013 18.7 0.2 0.003 17.5 0.2 1.6 1 0 0 1 1 1 1 PAN domain NARP1 PF12569.8 OWF51225.1 - 8.5 5.2 22.9 14 4.4 22.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.11 OWF51226.1 - 0.39 10.9 4.3 0.6 10.3 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) BRD4_CDT PF17105.5 OWF51227.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Ribosomal_L29 PF00831.23 OWF51227.1 - 2.6 8.1 4.7 0.8 9.7 0.6 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein Dehydrin PF00257.19 OWF51227.1 - 8.9 6.8 8.8 6.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Dehydrin zf-RING_UBOX PF13445.6 OWF51228.1 - 1.1e-10 41.4 7.0 1.1e-10 41.4 7.0 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF51228.1 - 3e-09 36.6 11.3 3e-09 36.6 11.3 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51228.1 - 1.2e-07 31.9 10.4 1.2e-07 31.9 10.4 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF51228.1 - 3.7e-07 30.2 12.0 3.7e-07 30.2 12.0 3.6 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF51228.1 - 7.3e-07 29.0 9.0 7.3e-07 29.0 9.0 4.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF51228.1 - 1.1e-06 28.4 7.6 1.1e-06 28.4 7.6 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF51228.1 - 6.5e-06 25.9 10.6 6.5e-06 25.9 10.6 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF51228.1 - 0.00031 20.5 9.7 0.00031 20.5 9.7 3.8 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 OWF51228.1 - 0.0011 19.1 9.3 0.0011 19.1 9.3 4.8 4 2 0 4 4 4 1 B-box zinc finger NUC130_3NT PF08158.12 OWF51228.1 - 0.26 11.6 0.1 0.26 11.6 0.1 1.7 2 0 0 2 2 2 0 NUC130/3NT domain SGL PF08450.12 OWF51229.1 - 0.025 14.1 0.1 0.11 12.1 0.0 2.0 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DHR10 PF18595.1 OWF51229.1 - 0.04 14.0 0.1 0.076 13.1 0.1 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF5024 PF16427.5 OWF51229.1 - 0.053 13.9 0.9 0.11 12.8 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) SBBP PF06739.11 OWF51229.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Beta-propeller repeat Nab2 PF11517.8 OWF51230.1 - 0.13 12.6 3.1 2 8.7 0.2 3.3 2 1 2 4 4 4 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Pox_A_type_inc PF04508.12 OWF51230.1 - 1.1 9.2 12.3 13 5.8 4.8 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Vac_Fusion PF02346.16 OWF51230.1 - 1.7 8.3 13.7 1.6 8.4 1.4 4.1 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF745 PF05335.13 OWF51230.1 - 2.2 7.9 42.3 0.031 14.0 6.2 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF745) GAS PF13851.6 OWF51230.1 - 6.3 6.1 60.7 0.039 13.3 34.2 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spore_YhaL PF14147.6 OWF51232.1 - 7.4e-09 35.2 5.0 31 4.4 0.0 7.8 1 1 11 12 12 12 11 Sporulation protein YhaL DUF3461 PF11944.8 OWF51232.1 - 1.3e-07 31.8 0.0 40 4.4 0.0 8.2 1 1 11 12 12 12 1 Protein of unknown function (DUF3461) Av_adeno_fibre PF06536.11 OWF51232.1 - 2.7e-06 27.2 17.9 1.1e+02 2.7 0.1 10.8 1 1 11 12 12 12 0 Avian adenovirus fibre, N-terminal Cna_B PF05738.13 OWF51232.1 - 2.3 8.8 5.4 3.3e+02 1.9 2.3 5.7 1 1 1 2 2 2 0 Cna protein B-type domain CBF PF03914.17 OWF51234.1 - 0.068 13.2 0.1 4.8 7.2 0.1 3.9 1 1 0 1 1 1 0 CBF/Mak21 family Qua1 PF16274.5 OWF51234.1 - 0.87 9.5 19.8 74 3.3 0.0 10.2 15 0 0 15 15 15 0 Qua1 domain FANCF PF11107.8 OWF51234.1 - 2.7 7.1 14.1 23 4.0 0.9 4.2 2 1 1 3 3 3 0 Fanconi anemia group F protein (FANCF) Gly_acyl_tr_C PF08444.10 OWF51235.1 - 0.095 12.9 2.6 22 5.4 0.1 3.6 1 1 2 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region CXCR4_N PF12109.8 OWF51235.1 - 0.55 10.5 1.4 1.5e+02 2.7 0.0 3.9 4 1 1 5 5 5 0 CXCR4 Chemokine receptor N terminal EF-hand_7 PF13499.6 OWF51237.1 - 0.00023 21.5 1.3 0.00068 20.0 1.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF51237.1 - 0.0025 17.6 0.8 0.03 14.2 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 OWF51237.1 - 0.19 11.5 2.3 0.41 10.4 0.4 2.3 3 0 0 3 3 3 0 SurA N-terminal domain GST_C_3 PF14497.6 OWF51238.1 - 1.4e-15 57.3 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF51238.1 - 4.1e-11 43.1 0.0 7.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF51238.1 - 1.3e-06 28.6 0.0 2.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF51238.1 - 0.0018 18.6 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Arf PF00025.21 OWF51239.1 - 1.5e-45 154.8 0.1 1.9e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OWF51239.1 - 2.9e-18 66.0 0.0 3.3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF51239.1 - 2.7e-16 59.9 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OWF51239.1 - 8.5e-10 38.4 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF51239.1 - 3.2e-08 33.1 0.1 3.5e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OWF51239.1 - 6.6e-08 32.2 0.0 8.3e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF51239.1 - 3.5e-06 27.1 0.0 6.8e-06 26.2 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OWF51239.1 - 0.065 13.3 0.0 3.4 7.7 0.1 2.1 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 OWF51239.1 - 0.13 12.0 0.0 4.4 7.0 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein VirE PF05272.11 OWF51239.1 - 0.15 11.8 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Peptidase_C1 PF00112.23 OWF51240.1 - 5.6e-63 212.9 4.0 1.1e-62 212.0 4.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 OWF51240.1 - 1.8e-46 157.3 1.3 3.7e-46 156.3 1.3 1.5 1 0 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 OWF51240.1 - 6.3e-05 21.9 1.1 0.00093 18.1 0.1 2.7 3 0 0 3 3 3 1 Peptidase C1-like family Propeptide_C1 PF08127.13 OWF51240.1 - 0.00018 21.3 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide PIG-P PF08510.12 OWF51241.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 PIG-P ATP19 PF11022.8 OWF51241.1 - 0.25 11.7 0.5 0.44 11.0 0.1 1.6 2 0 0 2 2 2 0 ATP synthase subunit K Galactosyl_T PF01762.21 OWF51242.1 - 1.2e-43 149.2 0.1 2.3e-43 148.3 0.1 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF51242.1 - 0.028 13.9 0.4 0.15 11.5 0.4 2.3 1 1 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 OWF51243.1 - 1.1e-43 149.4 0.4 1.6e-43 148.8 0.4 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF51243.1 - 0.004 16.6 0.9 0.0086 15.5 0.9 1.6 1 1 0 1 1 1 1 Fringe-like Homeodomain PF00046.29 OWF51244.1 - 4.9e-22 77.5 0.5 9.3e-22 76.6 0.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF51244.1 - 1.3e-05 25.0 0.2 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain Tetraspanin PF00335.20 OWF51245.1 - 2.6e-48 164.8 14.3 2.9e-48 164.6 14.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Exo_endo_phos PF03372.23 OWF51246.1 - 5.6e-05 22.8 0.4 0.00036 20.1 0.4 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNA_polI_A34 PF08208.11 OWF51248.1 - 6.9e-16 59.0 1.3 6.9e-16 59.0 1.3 3.5 2 2 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 OWF51248.1 - 2.4 6.8 6.7 3.4 6.3 6.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4691 PF15762.5 OWF51248.1 - 4.4 7.4 10.2 17 5.5 4.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4691) Bap31 PF05529.12 OWF51249.1 - 2e-44 150.7 6.2 2e-44 150.7 6.2 1.5 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OWF51249.1 - 1.7e-10 40.7 11.5 1.7e-10 40.7 11.5 2.6 2 2 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 OWF51249.1 - 0.00092 18.6 4.3 0.00092 18.6 4.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) DUF3810 PF12725.7 OWF51249.1 - 0.0014 18.0 3.6 0.0023 17.4 3.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) UPF0242 PF06785.11 OWF51249.1 - 0.0059 16.7 9.3 0.012 15.8 9.3 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 OWF51249.1 - 0.013 14.1 6.4 0.016 13.9 6.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3627 PF12299.8 OWF51249.1 - 0.028 14.5 0.7 0.054 13.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) Cluap1 PF10234.9 OWF51249.1 - 0.029 13.8 8.5 0.041 13.3 8.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TolA_bind_tri PF16331.5 OWF51249.1 - 0.12 12.5 7.7 2.7 8.1 1.1 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation JIP_LZII PF16471.5 OWF51249.1 - 0.26 11.5 7.9 3 8.1 0.5 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 OWF51249.1 - 0.31 9.9 16.0 0.42 9.4 16.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CAF-1_p150 PF11600.8 OWF51249.1 - 0.39 10.4 16.2 0.53 10.0 16.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WASH-7_C PF14746.6 OWF51249.1 - 0.39 10.4 6.7 1.2 8.7 6.7 1.8 1 1 0 1 1 1 0 WASH complex subunit 7, C-terminal CRA PF06589.11 OWF51249.1 - 1.8 8.7 8.5 0.44 10.7 1.7 2.5 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) AAA PF00004.29 OWF51250.1 - 1.2e-12 48.4 0.0 3e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 OWF51250.1 - 0.0052 16.5 1.0 0.012 15.3 1.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF815 PF05673.13 OWF51250.1 - 0.015 14.5 0.0 0.04 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 OWF51250.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OWF51250.1 - 0.12 12.4 0.0 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CECR6_TMEM121 PF14997.6 OWF51251.1 - 7.3e-44 150.0 8.8 1.2e-43 149.3 8.8 1.3 1 0 0 1 1 1 1 CECR6/TMEM121 family zf-CCCH_4 PF18044.1 OWF51252.1 - 1e-18 66.7 34.6 3.9e-08 32.9 2.2 4.7 4 0 0 4 4 4 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OWF51252.1 - 2e-16 59.4 35.3 4.7e-05 23.3 4.3 4.9 4 1 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 OWF51252.1 - 1.3e-15 56.8 31.3 6.7e-05 22.7 1.3 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OWF51252.1 - 1.6e-14 54.5 19.8 0.0014 19.3 1.5 4.4 3 1 1 4 4 4 4 Torus domain zf-C3HC4 PF00097.25 OWF51252.1 - 2.5e-07 30.5 5.7 2.5e-07 30.5 5.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51252.1 - 1.2e-06 28.8 6.1 1.2e-06 28.8 6.1 3.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF51252.1 - 1e-05 25.5 2.3 3.1e-05 23.9 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF51252.1 - 8.4e-05 22.5 5.0 8.4e-05 22.5 5.0 3.1 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF51252.1 - 0.00016 21.7 3.8 0.0009 19.4 3.8 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OWF51252.1 - 0.00093 19.4 4.5 0.00093 19.4 4.5 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-CCCH_3 PF15663.5 OWF51252.1 - 0.001 19.3 4.0 0.001 19.3 4.0 3.2 4 0 0 4 4 4 1 Zinc-finger containing family BRD4_CDT PF17105.5 OWF51252.1 - 0.0015 18.1 0.5 0.0027 17.3 0.5 1.4 1 0 0 1 1 1 1 C-terminal domain of bromodomain protein 4 zf-C3HC4_2 PF13923.6 OWF51252.1 - 0.0036 17.1 13.1 0.0084 15.9 8.4 3.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 OWF51252.1 - 0.0096 16.4 38.7 0.016 15.6 0.9 4.9 5 0 0 5 5 4 3 RNA-binding, Nab2-type zinc finger zf-RING_11 PF17123.5 OWF51252.1 - 0.01 15.6 3.5 0.04 13.7 3.5 2.1 1 0 0 1 1 1 0 RING-like zinc finger Cript PF10235.9 OWF51252.1 - 0.02 15.5 0.1 0.02 15.5 0.1 3.2 3 1 1 4 4 2 0 Microtubule-associated protein CRIPT DUF4929 PF16283.5 OWF51252.1 - 0.052 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) zf-UDP PF14569.6 OWF51252.1 - 0.66 10.1 12.2 0.038 14.1 2.4 3.2 3 0 0 3 3 3 0 Zinc-binding RING-finger WD40 PF00400.32 OWF51253.1 - 4.5e-22 77.9 21.8 0.00061 20.5 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF51253.1 - 2.9e-09 37.1 3.6 0.053 13.8 0.4 4.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF51253.1 - 0.0084 15.1 2.6 0.27 10.2 0.1 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1041 PF06292.17 OWF51254.1 - 2.2e-32 111.6 2.5 2.2e-32 111.6 2.5 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) PH PF00169.29 OWF51254.1 - 7.3e-09 36.1 0.0 2.2e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 PH domain Rep_3 PF01051.21 OWF51254.1 - 0.011 15.6 0.4 0.028 14.2 0.4 1.7 1 0 0 1 1 1 0 Initiator Replication protein Filament PF00038.21 OWF51254.1 - 0.04 13.5 6.5 0.18 11.3 2.0 3.0 3 1 0 3 3 3 0 Intermediate filament protein PAP1 PF08601.10 OWF51254.1 - 0.11 12.2 4.6 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 PHD PF00628.29 OWF51255.1 - 2.6e-08 33.6 12.2 7.7e-08 32.1 12.2 1.9 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OWF51255.1 - 0.0085 15.6 7.6 0.021 14.3 7.6 1.7 1 0 0 1 1 1 1 PHD-finger Fer4_8 PF13183.6 OWF51255.1 - 0.011 16.1 1.1 0.11 13.0 1.1 2.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pex26 PF07163.12 OWF51256.1 - 1.1e-35 123.4 0.5 1.4e-35 123.1 0.5 1.0 1 0 0 1 1 1 1 Pex26 protein DUF1700 PF08006.11 OWF51256.1 - 0.055 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Peptidase_M28 PF04389.17 OWF51257.1 - 3e-14 53.2 0.0 4.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OWF51257.1 - 6.4e-10 38.9 0.0 1.8e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 OWF51257.1 - 0.052 13.0 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Nicastrin Ldl_recept_a PF00057.18 OWF51259.1 - 1.1e-15 57.6 29.7 2.2e-11 43.8 10.0 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A ORC_WH_C PF18137.1 OWF51260.1 - 0.042 13.9 0.1 1e+02 3.0 0.0 4.3 2 1 2 4 4 4 0 Origin recognition complex winged helix C-terminal DUF5335 PF17269.2 OWF51260.1 - 9.8 6.1 5.9 16 5.4 0.2 3.3 1 1 2 4 4 4 0 Family of unknown function (DUF5335) NHL PF01436.21 OWF51261.1 - 4.8e-07 29.5 5.8 0.19 11.8 0.0 5.3 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 OWF51261.1 - 0.00033 20.3 0.1 0.36 10.4 0.0 3.9 1 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 OWF51261.1 - 0.021 15.0 8.7 0.021 15.0 8.7 2.1 2 0 0 2 2 2 0 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF51261.1 - 0.22 11.4 11.5 3 7.8 6.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.16 OWF51261.1 - 0.68 9.9 4.6 0.87 9.5 1.0 2.4 2 0 0 2 2 2 0 HIT zinc finger IBR PF01485.21 OWF51261.1 - 0.83 9.9 8.4 3.3 8.0 8.4 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OWF51261.1 - 2.8 8.4 11.3 11 6.4 0.2 2.6 2 0 0 2 2 2 0 Ring finger domain AMP-binding PF00501.28 OWF51263.1 - 4.9e-60 203.3 0.0 5.7e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51263.1 - 7.8e-08 33.2 0.0 1.9e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF51264.1 - 1.5e-62 211.6 0.0 1.8e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51264.1 - 2e-07 31.9 0.0 3.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SRCR PF00530.18 OWF51265.1 - 3.2e-94 309.9 18.0 2.6e-24 85.6 0.9 4.0 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF51265.1 - 3.2e-13 50.0 14.8 5.9e-05 23.5 0.1 4.2 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain REGB_T4 PF10715.9 OWF51265.1 - 4e-05 23.9 0.0 0.43 10.8 0.0 3.7 4 0 0 4 4 4 2 T4-page Endoribonuclease RegB Hepsin-SRCR PF09272.10 OWF51265.1 - 0.00011 22.7 1.0 0.81 10.2 0.0 4.0 4 0 0 4 4 4 1 Hepsin, SRCR domain Peptidase_C97 PF05903.14 OWF51265.1 - 0.00041 20.2 4.0 0.29 10.9 0.1 3.8 4 0 0 4 4 4 1 PPPDE putative peptidase domain DUF5640 PF18692.1 OWF51265.1 - 0.027 14.5 0.0 13 5.9 0.0 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5640) Glyco_hydro_59M PF17387.2 OWF51265.1 - 0.06 13.5 0.0 13 5.9 0.0 3.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 59 central domain LSPR PF06049.12 OWF51267.1 - 0.0018 17.8 29.8 33 4.9 0.1 9.1 12 0 0 12 12 12 7 Coagulation Factor V LSPD Repeat Ribosomal_L30 PF00327.20 OWF51268.1 - 2.7e-39 132.8 0.0 25 4.8 0.0 23.6 1 1 43 44 44 44 44 Ribosomal protein L30p/L7e NDK PF00334.19 OWF51269.1 - 4.6e-116 382.8 0.1 1.3e-38 132.0 0.0 4.0 3 1 1 4 4 4 3 Nucleoside diphosphate kinase Thioredoxin PF00085.20 OWF51269.1 - 1.8e-08 34.3 0.0 5.6e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin DNA_pol3_a_NII PF11490.8 OWF51269.1 - 0.00026 20.8 5.9 0.00026 20.8 5.9 6.2 2 1 3 5 5 5 1 DNA polymerase III polC-type N-terminus II Arg_repressor PF01316.21 OWF51269.1 - 0.81 9.5 6.4 5.6 6.8 0.1 3.5 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain Vps8 PF12816.7 OWF51270.1 - 4.1e-65 219.0 3.1 2.8e-62 209.8 0.1 3.1 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OWF51270.1 - 1.9e-12 47.3 8.2 2.5e-08 33.9 0.1 4.3 4 1 0 4 4 4 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 OWF51270.1 - 0.0024 18.2 0.1 0.28 11.5 0.0 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_1 PF14446.6 OWF51270.1 - 0.0081 16.1 0.9 0.025 14.5 0.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.29 OWF51270.1 - 0.47 10.4 6.5 0.34 10.8 3.5 2.3 2 0 0 2 2 2 0 PHD-finger SET_assoc PF11767.8 OWF51271.1 - 0.13 11.9 0.1 0.43 10.2 0.1 1.9 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated PMP1_2 PF08114.11 OWF51271.1 - 2 8.2 4.5 0.39 10.5 0.3 1.9 2 0 0 2 2 2 0 ATPase proteolipid family zf-B_box PF00643.24 OWF51273.1 - 0.00019 21.5 31.7 0.00039 20.5 7.3 3.0 2 1 0 2 2 2 2 B-box zinc finger C1_2 PF03107.16 OWF51273.1 - 0.029 14.7 3.9 0.029 14.7 3.9 2.9 2 1 1 3 3 3 0 C1 domain DUF899 PF05988.12 OWF51273.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) FYVE_2 PF02318.16 OWF51273.1 - 7 6.9 23.8 4.2 7.6 7.2 2.5 1 1 1 2 2 2 0 FYVE-type zinc finger zf-UDP PF14569.6 OWF51273.1 - 9.1 6.5 18.4 1.8 8.8 4.0 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger NHL PF01436.21 OWF51274.1 - 0.036 14.1 0.4 0.086 12.9 0.4 1.6 1 0 0 1 1 1 0 NHL repeat Syndecan PF01034.20 OWF51275.1 - 0.063 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Neur_chan_LBD PF02931.23 OWF51276.1 - 1.2e-44 152.4 0.3 1.7e-44 151.8 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51276.1 - 2e-18 67.4 15.5 1.9e-16 60.9 9.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region LPG_synthase_TM PF03706.13 OWF51276.1 - 0.00012 21.8 0.6 0.002 17.7 0.1 2.3 2 1 0 2 2 2 1 Lysylphosphatidylglycerol synthase TM region Neur_chan_LBD PF02931.23 OWF51277.1 - 4.8e-46 156.9 3.8 6.6e-46 156.5 3.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51277.1 - 4.8e-12 46.5 14.5 1.3e-10 41.7 7.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF51279.1 - 4.8e-46 156.9 3.8 6.6e-46 156.5 3.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51279.1 - 4.8e-12 46.5 14.5 1.3e-10 41.7 7.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4744 PF15918.5 OWF51280.1 - 0.071 14.0 0.0 0.21 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Neur_chan_LBD PF02931.23 OWF51281.1 - 2.5e-42 144.8 0.7 3.3e-42 144.4 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51281.1 - 3.7e-11 43.5 17.8 4.4e-11 43.3 9.9 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF51282.1 - 1.2e-43 149.1 0.7 1.7e-43 148.6 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51282.1 - 7.7e-15 55.6 15.6 1.4e-13 51.5 7.9 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF51283.1 - 1e-45 155.8 0.9 1.5e-45 155.3 0.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51283.1 - 8.2e-24 85.0 15.6 1.6e-19 70.9 7.8 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Octopine_DH PF02317.17 OWF51284.1 - 6.1e-33 114.0 0.0 8.7e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain ApbA PF02558.16 OWF51284.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OWF51284.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 OWF51284.1 - 0.14 13.0 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Neur_chan_LBD PF02931.23 OWF51285.1 - 1.1e-14 54.4 0.1 1.4e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51285.1 - 3.3e-11 43.7 5.3 4.6e-11 43.2 5.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF51286.1 - 2e-14 53.6 0.1 2.2e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ARL2_Bind_BART PF11527.8 OWF51286.1 - 0.097 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART DUF2514 PF10721.9 OWF51287.1 - 0.035 14.1 2.9 0.042 13.9 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TPR_12 PF13424.6 OWF51288.1 - 4.9e-21 74.8 14.5 1.1e-07 32.1 0.0 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF51288.1 - 1.2e-20 71.9 15.7 0.0067 16.5 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 OWF51288.1 - 4.5e-19 67.4 10.6 0.01 15.6 0.1 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 OWF51288.1 - 1.7e-13 49.6 10.0 0.00086 19.2 0.0 8.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF51288.1 - 2e-13 49.4 12.3 0.27 11.6 0.1 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF51288.1 - 2e-09 37.8 8.3 0.0074 16.8 0.5 5.6 3 3 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF51288.1 - 1.1e-07 31.9 4.5 0.00056 20.1 0.6 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OWF51288.1 - 1.5e-07 31.6 7.6 1.2 10.1 0.7 6.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF51288.1 - 4.1e-07 29.7 5.3 8.1e-06 25.4 0.8 2.5 2 1 0 2 2 2 2 MalT-like TPR region TPR_6 PF13174.6 OWF51288.1 - 1.4e-06 28.5 3.5 8.3 7.3 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF51288.1 - 2e-06 27.8 2.4 0.38 10.9 0.7 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF51288.1 - 3.9e-06 27.4 6.6 0.8 10.4 0.0 5.5 5 2 1 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF51288.1 - 4.7e-06 26.6 1.4 4.2 8.0 0.1 5.5 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF51288.1 - 0.00016 21.3 4.8 8 6.2 0.0 5.2 5 0 0 5 5 5 1 TPR repeat TPR_4 PF07721.14 OWF51288.1 - 0.00028 21.2 1.1 0.97 10.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 OWF51288.1 - 0.0005 19.8 4.4 0.0014 18.4 0.1 3.6 2 2 2 4 4 4 1 26S proteasome subunit RPN7 DUF3856 PF12968.7 OWF51288.1 - 0.00097 19.2 5.6 1.7 8.7 0.1 4.7 3 2 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 OWF51288.1 - 0.0022 17.8 11.3 1.2 9.1 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 OWF51288.1 - 0.024 14.7 2.5 2.2 8.5 0.0 3.8 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region AKAP7_RIRII_bdg PF10470.9 OWF51288.1 - 0.024 14.7 0.4 0.11 12.6 0.1 2.3 2 0 0 2 2 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein NusB PF01029.18 OWF51288.1 - 0.067 13.4 1.7 4.7 7.4 0.0 3.3 3 0 0 3 3 3 0 NusB family BTAD PF03704.17 OWF51288.1 - 0.6 10.5 10.2 0.18 12.2 1.0 3.4 3 1 0 4 4 3 0 Bacterial transcriptional activator domain P4Ha_N PF08336.11 OWF51289.1 - 4.8e-14 52.5 0.1 9.9e-14 51.5 0.1 1.6 1 1 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_2 PF07719.17 OWF51289.1 - 0.0035 17.3 0.0 0.19 11.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF51289.1 - 0.13 13.1 0.0 0.42 11.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat fn3 PF00041.21 OWF51290.1 - 5.8e-31 106.7 7.4 3.3e-10 40.2 0.0 5.5 5 1 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OWF51290.1 - 2.2e-05 24.9 0.6 1.2 9.7 0.1 4.2 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 OWF51290.1 - 0.00051 20.3 0.4 0.71 10.2 0.0 4.0 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III DUF1281_C PF18406.1 OWF51290.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein DUF2369 PF10179.9 OWF51290.1 - 0.13 12.6 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Cu2_monooxygen PF01082.20 OWF51291.1 - 2.8e-16 60.0 0.0 4.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF51291.1 - 2e-07 30.6 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain CAP_GLY PF01302.25 OWF51292.1 - 2e-18 66.2 0.3 3.7e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain TSC22 PF01166.18 OWF51292.1 - 0.045 14.1 0.2 0.36 11.2 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 OWF51292.1 - 0.056 13.3 0.8 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF2407_C PF13373.6 OWF51292.1 - 0.12 12.6 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain ATG16 PF08614.11 OWF51292.1 - 1.8 8.8 7.1 4.4 7.5 0.1 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) zf-C4 PF00105.18 OWF51293.1 - 2.7e-30 104.6 17.5 5.5e-30 103.6 17.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF51293.1 - 1.5e-20 73.7 0.1 2.6e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor FA_desaturase PF00487.24 OWF51294.1 - 2.7e-36 125.7 25.3 3.6e-36 125.3 25.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OWF51294.1 - 1.7e-22 79.4 0.6 3.4e-22 78.4 0.6 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IBR PF01485.21 OWF51295.1 - 1e-20 73.7 23.8 8.7e-14 51.5 1.8 5.4 5 1 1 6 6 6 2 IBR domain, a half RING-finger domain Ank_2 PF12796.7 OWF51295.1 - 7.2e-10 39.3 3.9 0.00032 21.2 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF51295.1 - 1e-09 38.4 0.8 0.00039 20.7 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OWF51295.1 - 4.5e-09 36.7 1.6 0.0047 17.5 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF51295.1 - 2.8e-08 33.9 1.8 0.00032 20.9 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF51295.1 - 4.3e-07 29.7 3.3 0.069 13.7 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat zf-RING_2 PF13639.6 OWF51295.1 - 0.0024 18.2 9.7 0.0024 18.2 9.7 4.9 4 1 1 5 5 5 2 Ring finger domain UIM PF02809.20 OWF51295.1 - 6.5 6.9 11.7 41 4.4 0.0 3.9 3 0 0 3 3 3 0 Ubiquitin interaction motif Recep_L_domain PF01030.24 OWF51296.1 - 2.7e-21 75.8 0.0 3.6e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Receptor L domain GF_recep_IV PF14843.6 OWF51296.1 - 0.062 13.1 1.1 0.12 12.2 1.1 1.4 1 0 0 1 1 1 0 Growth factor receptor domain IV Peptidase_M76 PF09768.9 OWF51300.1 - 2.9e-43 147.6 6.8 3.5e-43 147.3 6.8 1.1 1 0 0 1 1 1 1 Peptidase M76 family Sulfotransfer_1 PF00685.27 OWF51301.1 - 1.4e-07 31.2 0.2 1.8e-07 30.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF51301.1 - 3.6e-05 24.3 0.2 6.2e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Sulfotransferase family DUF1891 PF09004.10 OWF51301.1 - 0.1 12.2 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) Fibrinogen_C PF00147.18 OWF51302.1 - 2.2e-52 178.1 3.8 3.2e-52 177.5 3.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF51302.1 - 0.12 12.3 5.5 0.23 11.5 5.5 1.6 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 OWF51302.1 - 0.61 10.0 5.3 0.3 11.0 2.8 1.8 2 0 0 2 2 2 0 PAN domain CFC PF09443.10 OWF51302.1 - 2.9 7.8 6.5 0.5 10.2 1.1 2.3 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) DUF480 PF04337.12 OWF51304.1 - 0.054 13.6 0.3 0.083 13.0 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function, DUF480 DUF1664 PF07889.12 OWF51304.1 - 0.07 13.2 0.1 0.086 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Trypsin PF00089.26 OWF51305.1 - 6.7e-47 160.1 0.9 7.9e-47 159.9 0.9 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF51305.1 - 6e-05 24.0 0.5 9.5e-05 23.3 0.5 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Tyrosinase PF00264.20 OWF51306.1 - 7.3e-21 75.5 4.8 1.6e-18 67.8 1.0 3.3 2 1 0 2 2 2 1 Common central domain of tyrosinase MYO10_CC PF16735.5 OWF51306.1 - 0.027 14.6 0.1 0.077 13.1 0.1 1.7 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain SRA1 PF07304.11 OWF51306.1 - 0.15 11.9 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Spectrin PF00435.21 OWF51307.1 - 7.9e-93 305.9 153.9 1.2e-11 45.0 4.5 20.4 17 2 3 20 20 20 16 Spectrin repeat Plectin PF00681.20 OWF51307.1 - 6.4e-56 186.0 2.6 1.3e-06 28.2 0.0 15.2 14 1 1 15 15 15 11 Plectin repeat GAS2 PF02187.17 OWF51307.1 - 9.4e-30 102.5 0.1 3e-29 100.9 0.1 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SH3_10 PF17902.1 OWF51307.1 - 2.9e-20 72.1 0.0 1.2e-19 70.2 0.0 2.2 1 0 0 1 1 1 1 SH3 domain EF-hand_6 PF13405.6 OWF51307.1 - 0.0015 18.3 2.7 0.039 13.9 0.1 3.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OWF51307.1 - 0.0024 18.3 2.5 0.0024 18.3 2.5 4.8 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF51307.1 - 0.0037 16.7 6.7 0.049 13.2 0.1 3.9 3 0 0 3 3 3 1 EF hand DASH_Dad1 PF08649.10 OWF51307.1 - 0.021 15.0 2.9 0.51 10.6 0.1 4.7 4 0 0 4 4 4 0 DASH complex subunit Dad1 EF-hand_8 PF13833.6 OWF51307.1 - 2.3 8.1 9.0 0.27 11.1 0.8 3.9 4 1 1 5 5 5 0 EF-hand domain pair IPK PF03770.16 OWF51308.1 - 9.2e-35 120.3 0.2 2.4e-34 118.9 0.2 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase TPR_12 PF13424.6 OWF51309.1 - 9.9e-74 243.6 28.7 5.5e-23 81.1 1.4 7.5 3 2 4 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 OWF51309.1 - 5.1e-56 185.1 28.3 9.6e-12 44.4 0.4 9.6 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 OWF51309.1 - 2.6e-35 118.8 28.0 7.7e-07 28.7 0.9 9.1 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 OWF51309.1 - 6.4e-32 107.2 20.5 3.1e-06 26.8 0.4 9.2 9 1 0 9 9 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 OWF51309.1 - 4.1e-23 79.6 27.3 0.00026 21.0 0.8 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 OWF51309.1 - 5.6e-22 76.0 29.1 2.8e-05 23.9 0.9 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF51309.1 - 3.8e-18 66.0 22.4 5.5e-11 42.4 0.9 4.1 3 1 2 5 5 5 3 MalT-like TPR region TPR_16 PF13432.6 OWF51309.1 - 1e-16 61.3 16.5 9.3e-09 35.8 1.1 6.5 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 OWF51309.1 - 7.7e-10 38.5 10.0 0.12 12.8 0.1 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF51309.1 - 1.2e-09 38.2 18.8 0.2 12.6 0.2 7.7 5 3 3 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OWF51309.1 - 1.5e-08 35.1 17.7 0.00063 20.2 0.6 5.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF51309.1 - 6.8e-08 32.1 28.3 0.0011 18.6 0.6 7.6 9 0 0 9 9 7 3 TPR repeat NACHT PF05729.12 OWF51309.1 - 6.9e-08 32.6 0.1 1.7e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 NACHT domain DUF2225 PF09986.9 OWF51309.1 - 9.4e-06 25.5 11.8 0.094 12.4 0.7 4.1 2 1 1 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 OWF51309.1 - 0.00021 21.6 0.1 1.2 10.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF51309.1 - 0.00036 20.7 13.9 0.017 15.3 1.2 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 OWF51309.1 - 0.00037 20.5 21.1 0.037 14.1 1.2 5.9 3 2 2 5 5 5 2 MIT (microtubule interacting and transport) domain RPN6_N PF18055.1 OWF51309.1 - 0.0014 18.9 7.0 0.49 10.8 0.2 4.3 2 1 1 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain AAA_16 PF13191.6 OWF51309.1 - 0.0021 18.5 0.0 0.017 15.5 0.0 2.6 1 0 0 1 1 1 1 AAA ATPase domain 14-3-3 PF00244.20 OWF51309.1 - 0.025 14.1 10.1 0.15 11.5 1.0 3.2 2 1 2 4 4 4 0 14-3-3 protein TPR_9 PF13371.6 OWF51309.1 - 0.036 14.2 7.9 1.8 8.8 0.0 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat bZIP_1 PF00170.21 OWF51309.1 - 0.077 13.1 3.5 0.31 11.2 3.5 2.1 1 0 0 1 1 1 0 bZIP transcription factor AAA_22 PF13401.6 OWF51309.1 - 0.083 13.2 0.0 0.55 10.5 0.0 2.5 2 0 0 2 2 1 0 AAA domain TPR_6 PF13174.6 OWF51309.1 - 0.12 13.0 26.3 0.51 11.1 0.4 7.4 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 OWF51309.1 - 1.4 9.0 23.5 1.7 8.7 0.3 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Tcf25 PF04910.14 OWF51309.1 - 1.7 7.7 5.5 12 4.9 0.2 4.1 2 1 4 6 6 6 0 Transcriptional repressor TCF25 kleA_kleC PF17383.2 OWF51309.1 - 1.9 8.9 5.3 12 6.3 1.9 3.5 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A YabA PF06156.13 OWF51309.1 - 3 8.5 5.6 14 6.4 2.2 3.3 2 1 0 2 2 2 0 Initiation control protein YabA Recep_L_domain PF01030.24 OWF51310.1 - 8.1e-20 71.0 0.1 1.7e-19 70.0 0.1 1.5 1 1 0 1 1 1 1 Receptor L domain Furin-like PF00757.20 OWF51310.1 - 6.5e-13 48.8 21.7 1.1e-12 48.1 21.7 1.3 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 OWF51310.1 - 0.00015 21.5 21.9 0.00035 20.4 21.4 1.8 1 1 0 1 1 1 1 Growth factor receptor domain IV EGF_3 PF12947.7 OWF51311.1 - 9.5e-13 48.1 27.9 1.5e-08 34.7 10.9 2.5 2 1 0 2 2 2 2 EGF domain EGF_MSP1_1 PF12946.7 OWF51311.1 - 9.3e-08 32.0 22.3 1.4e-06 28.2 6.2 2.3 2 0 0 2 2 2 2 MSP1 EGF domain 1 EGF_CA PF07645.15 OWF51311.1 - 2.8e-07 30.6 9.5 2.8e-07 30.6 9.5 2.6 2 1 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 OWF51311.1 - 0.0031 17.4 14.3 0.0077 16.1 4.0 3.0 2 1 1 3 3 3 2 Complement Clr-like EGF-like hEGF PF12661.7 OWF51311.1 - 0.0039 17.8 19.0 0.027 15.1 1.4 4.0 3 1 1 4 4 4 2 Human growth factor-like EGF EGF PF00008.27 OWF51311.1 - 0.013 15.8 23.0 0.024 14.9 6.1 2.5 2 0 0 2 2 2 0 EGF-like domain EB PF01683.18 OWF51311.1 - 0.22 11.9 21.3 0.36 11.2 7.3 2.3 2 0 0 2 2 2 0 EB module Plasmod_Pvs28 PF06247.11 OWF51311.1 - 2 8.8 19.7 0.98 9.8 8.0 2.6 2 1 0 2 2 2 0 Pvs28 EGF domain BIV_Env PF05858.12 OWF51312.1 - 0.13 10.4 2.1 0.24 9.6 2.1 1.5 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) PAN_1 PF00024.26 OWF51313.1 - 0.00052 19.9 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 PAN domain Lectin_C PF00059.21 OWF51313.1 - 0.0034 18.1 0.0 0.0067 17.2 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain CLIP_SPH_mas PF18398.1 OWF51313.1 - 0.23 11.9 0.2 0.23 11.9 0.2 2.2 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade HTH_26 PF13443.6 OWF51314.1 - 4.1e-10 39.9 9.6 0.016 15.6 0.3 4.3 1 1 3 4 4 4 4 Cro/C1-type HTH DNA-binding domain AvrM_N PF18247.1 OWF51314.1 - 9e-05 22.3 3.5 3.8 7.5 0.1 4.3 1 1 4 5 5 5 3 Flax-rust effector AvrM N-terminal domain HU-CCDC81_euk_2 PF18289.1 OWF51314.1 - 0.0015 18.7 6.0 15 5.8 0.1 4.4 1 1 4 6 6 6 4 CCDC81 eukaryotic HU domain 2 GlutR_dimer PF00745.20 OWF51314.1 - 0.0041 17.5 3.8 0.39 11.2 3.4 2.5 1 1 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain Fibrinogen_BP PF08017.11 OWF51314.1 - 0.0048 15.4 18.2 0.0054 15.2 18.2 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein AlaDh_PNT_N PF05222.15 OWF51314.1 - 0.017 15.4 1.0 40 4.5 0.0 3.0 1 1 2 3 3 3 0 Alanine dehydrogenase/PNT, N-terminal domain HTH_31 PF13560.6 OWF51314.1 - 0.025 14.9 13.3 8.2e+02 0.5 13.2 3.4 1 1 0 1 1 1 0 Helix-turn-helix domain CelTOS PF18659.1 OWF51314.1 - 0.2 12.1 0.2 4.5 7.7 0.1 2.1 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Gasdermin PF04598.12 OWF51316.1 - 1.9e-24 86.4 0.8 3.9e-24 85.4 0.1 1.9 2 0 0 2 2 2 1 Gasdermin pore forming domain Pentapeptide_4 PF13599.6 OWF51316.1 - 0.011 15.9 0.0 0.078 13.2 0.0 2.3 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Gasdermin PF04598.12 OWF51317.1 - 8.1e-22 77.8 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Gasdermin pore forming domain Pentapeptide_4 PF13599.6 OWF51318.1 - 0.0085 16.2 0.0 14 5.9 0.0 4.3 2 1 1 4 4 4 2 Pentapeptide repeats (9 copies) KRAP_IP3R_bind PF14722.6 OWF51319.1 - 3.1e-10 40.0 0.1 1.5e-09 37.8 0.1 2.2 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain SSFA2_C PF14723.6 OWF51319.1 - 1.7e-05 24.8 0.9 1.7e-05 24.8 0.9 3.2 3 0 0 3 3 3 1 Sperm-specific antigen 2 C-terminus Methyltransf_21 PF05050.12 OWF51320.1 - 0.00054 20.0 0.9 0.01 15.9 0.8 2.8 1 1 0 1 1 1 1 Methyltransferase FkbM domain HMA PF00403.26 OWF51320.1 - 0.056 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Heavy-metal-associated domain Ank_2 PF12796.7 OWF51321.1 - 3.3e-98 322.4 5.9 2e-17 63.5 0.2 8.3 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF51321.1 - 1.8e-87 286.7 12.7 1.6e-11 44.5 0.3 11.0 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 OWF51321.1 - 1e-75 247.1 18.7 4e-06 27.0 0.0 16.0 16 0 0 16 16 16 15 Ankyrin repeat Ank_5 PF13857.6 OWF51321.1 - 8.2e-74 242.7 10.9 1.3e-10 41.3 0.0 10.0 4 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF51321.1 - 1.9e-73 233.6 8.6 0.0006 20.1 0.0 16.3 16 0 0 16 16 16 15 Ankyrin repeat IQ PF00612.27 OWF51321.1 - 8e-07 28.3 17.7 0.00072 19.1 0.2 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif Gelsolin PF00626.22 OWF51322.1 - 1.1e-18 66.9 1.7 8.2e-05 22.4 0.0 5.8 6 0 0 6 6 6 3 Gelsolin repeat VHP PF02209.19 OWF51322.1 - 5.5e-15 55.1 0.8 1.7e-14 53.6 0.8 1.9 1 0 0 1 1 1 1 Villin headpiece domain Myb_CC_LHEQLE PF14379.6 OWF51323.1 - 1.1e-09 37.9 14.4 0.41 10.4 0.1 6.5 4 1 2 6 6 6 4 MYB-CC type transfactor, LHEQLE motif Spectrin PF00435.21 OWF51323.1 - 0.00093 19.7 12.5 0.1 13.1 0.6 4.2 1 1 3 4 4 4 2 Spectrin repeat DUF2274 PF10038.9 OWF51323.1 - 0.0025 18.2 0.3 1.6 9.3 0.0 3.7 1 1 2 4 4 4 1 Protein of unknown function (DUF2274) Nsp1_C PF05064.13 OWF51323.1 - 0.022 14.6 11.5 4 7.3 0.2 4.2 1 1 3 4 4 4 0 Nsp1-like C-terminal region Pih1_fungal_CS PF18482.1 OWF51323.1 - 0.027 15.0 14.6 0.65 10.5 0.6 3.9 1 1 3 4 4 4 0 Fungal Pih1 CS domain PKD_2 PF16407.5 OWF51323.1 - 0.074 13.2 6.4 5.9 7.0 0.3 2.9 1 1 2 3 3 3 0 PKD-like family DUF4790 PF16037.5 OWF51323.1 - 0.34 11.4 9.3 1.4 9.5 1.5 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4790) HiaBD2 PF15403.6 OWF51323.1 - 4.3 7.8 13.8 16 6.0 0.3 4.3 4 0 0 4 4 4 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Myb_CC_LHEQLE PF14379.6 OWF51324.1 - 0.00032 20.3 23.6 3.2 7.5 0.1 7.0 4 2 3 7 7 7 4 MYB-CC type transfactor, LHEQLE motif Invas_SpaK PF03519.14 OWF51324.1 - 0.0033 17.4 1.8 9 6.4 0.1 4.4 2 2 3 5 5 5 1 Invasion protein B family Spectrin PF00435.21 OWF51324.1 - 0.016 15.7 15.1 1.9 9.0 0.3 4.5 1 1 2 4 4 4 0 Spectrin repeat VHL_C PF17211.3 OWF51324.1 - 0.017 15.1 5.1 2.7 8.1 0.2 4.5 2 2 1 4 4 4 0 VHL box domain Endonuc-EcoRV PF09233.11 OWF51324.1 - 0.1 11.9 5.3 5.1 6.4 0.1 3.0 1 1 3 4 4 4 0 Restriction endonuclease EcoRV DUF5115 PF17142.4 OWF51324.1 - 0.25 11.0 8.2 6.3 6.4 0.3 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF5115) Pih1_fungal_CS PF18482.1 OWF51324.1 - 4.6 7.8 17.9 3.1 8.4 1.0 4.4 1 1 2 4 4 4 0 Fungal Pih1 CS domain HiaBD2 PF15403.6 OWF51324.1 - 7.4 7.0 15.8 82 3.7 0.1 6.7 5 1 2 7 7 7 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Nsp1_C PF05064.13 OWF51324.1 - 7.9 6.3 14.0 11 5.9 0.5 4.9 2 2 3 5 5 5 0 Nsp1-like C-terminal region Myb_CC_LHEQLE PF14379.6 OWF51325.1 - 0.00047 19.8 9.1 1.3 8.8 2.1 4.1 3 1 0 3 3 3 2 MYB-CC type transfactor, LHEQLE motif Spectrin PF00435.21 OWF51325.1 - 0.00094 19.6 5.4 0.5 10.9 0.6 2.5 1 1 2 3 3 3 2 Spectrin repeat NOD PF06816.13 OWF51325.1 - 0.0093 15.6 0.0 8.4 6.1 0.0 3.8 3 0 0 3 3 3 1 NOTCH protein Alk_phosphatase PF00245.20 OWF51325.1 - 0.011 14.7 4.3 0.03 13.3 1.1 1.9 1 1 1 2 2 2 0 Alkaline phosphatase Nsp1_C PF05064.13 OWF51325.1 - 0.037 13.8 7.0 3.1 7.6 0.4 3.1 1 1 2 3 3 3 0 Nsp1-like C-terminal region Aida_N PF08910.10 OWF51325.1 - 0.1 13.0 0.1 2 8.8 0.0 2.4 1 1 2 3 3 3 0 Aida N-terminus Pih1_fungal_CS PF18482.1 OWF51325.1 - 0.11 13.0 9.6 1.9 9.1 0.5 3.1 1 1 2 3 3 3 0 Fungal Pih1 CS domain PKD_2 PF16407.5 OWF51325.1 - 0.18 11.9 2.5 0.68 10.1 0.5 1.9 1 1 1 2 2 2 0 PKD-like family HiaBD2 PF15403.6 OWF51325.1 - 2.7 8.4 7.2 48 4.4 0.1 3.8 3 1 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Furin-like PF00757.20 OWF51327.1 - 4.6e-27 94.7 194.0 2e-06 27.7 5.2 14.9 1 1 12 13 13 13 12 Furin-like cysteine rich region Furin-like_2 PF15913.5 OWF51327.1 - 9.1e-05 22.6 24.7 0.00013 22.1 10.5 16.3 3 2 11 15 15 15 6 Furin-like repeat, cysteine-rich TIR_2 PF13676.6 OWF51328.1 - 6.1e-16 59.1 0.0 1.2e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF51328.1 - 3.3e-10 40.1 0.5 8.3e-10 38.7 0.5 1.7 1 0 0 1 1 1 1 TIR domain CdiA_C PF18451.1 OWF51328.1 - 0.011 16.0 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain DUF1863 PF08937.11 OWF51328.1 - 0.023 15.0 0.9 0.1 12.9 0.1 2.5 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) Glyco_transf_7N PF13733.6 OWF51329.1 - 3.9e-49 165.7 0.6 6.6e-49 165.0 0.6 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF51329.1 - 2.5e-23 81.5 0.3 5.4e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase TBPIP PF07106.13 OWF51330.1 - 1.2e-25 89.2 0.9 2.4e-25 88.3 0.9 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 OWF51330.1 - 2.1e-14 53.4 0.8 2.1e-14 53.4 0.8 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Spc24 PF08286.11 OWF51330.1 - 0.0081 16.4 0.7 0.033 14.4 0.7 2.0 1 1 0 1 1 1 1 Spc24 subunit of Ndc80 FlxA PF14282.6 OWF51330.1 - 0.28 11.2 4.0 0.29 11.1 0.7 2.2 1 1 1 2 2 2 0 FlxA-like protein YyzF PF14116.6 OWF51330.1 - 1.1 9.4 4.0 15 5.7 0.4 2.4 2 0 0 2 2 2 0 YyzF-like protein DUF2140 PF09911.9 OWF51331.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Ras PF00071.22 OWF51332.1 - 6.4e-42 142.9 0.0 7.9e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF51332.1 - 5.3e-24 84.7 0.0 7.2e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF51332.1 - 9.2e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF51332.1 - 4.6e-05 23.5 0.0 0.0001 22.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF51332.1 - 0.0006 19.4 0.0 0.016 14.8 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF51332.1 - 0.0038 16.6 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 OWF51332.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 OWF51332.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 OWF51332.1 - 0.13 12.2 0.0 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Glyco_tran_WbsX PF14307.6 OWF51332.1 - 0.21 11.0 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX Glycos_transf_2 PF00535.26 OWF51334.1 - 1.3e-33 116.3 0.0 2.3e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF51334.1 - 8.4e-20 71.3 0.6 1.4e-19 70.6 0.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 OWF51334.1 - 6.6e-08 32.4 0.0 3e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF51334.1 - 1.2e-05 24.9 0.4 2.5e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 OWF51334.1 - 0.092 13.5 0.0 0.51 11.1 0.0 2.2 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OWF51334.1 - 0.17 11.5 0.6 0.82 9.2 0.1 2.1 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain BTB PF00651.31 OWF51335.1 - 3.5e-16 59.4 0.2 8.7e-16 58.1 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain zf-AN1 PF01428.16 OWF51335.1 - 1.1 9.5 7.7 0.63 10.2 5.0 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger FYVE_2 PF02318.16 OWF51335.1 - 2.6 8.3 13.1 0.22 11.8 6.6 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger YrbL-PhoP_reg PF10707.9 OWF51337.1 - 0.075 12.5 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ATG16 PF08614.11 OWF51338.1 - 4.2e-05 23.9 5.9 5.2e-05 23.6 5.9 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OWF51338.1 - 0.0009 19.8 8.6 0.0012 19.3 8.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 OWF51338.1 - 0.0058 15.6 9.8 0.0071 15.3 9.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Phlebovirus_NSM PF07246.11 OWF51338.1 - 0.032 13.6 8.1 0.042 13.2 8.1 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4201 PF13870.6 OWF51338.1 - 0.049 13.4 12.1 0.071 12.8 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GrpE PF01025.19 OWF51338.1 - 0.11 12.2 8.8 0.14 11.8 8.8 1.3 1 0 0 1 1 1 0 GrpE Atg14 PF10186.9 OWF51338.1 - 0.37 9.8 10.7 0.46 9.5 10.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 OWF51338.1 - 0.58 10.0 8.5 0.76 9.6 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 OWF51338.1 - 0.77 9.8 17.1 0.35 10.9 11.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 OWF51338.1 - 1.4 8.2 8.2 1.8 7.8 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5339 PF17274.2 OWF51338.1 - 7.1 7.6 10.5 8.9 7.3 3.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5339) DegT_DnrJ_EryC1 PF01041.17 OWF51339.1 - 2.5e-26 92.8 0.0 5.5e-25 88.4 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OWF51339.1 - 0.034 13.3 0.1 0.079 12.1 0.1 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II Aminotran_5 PF00266.19 OWF51339.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V C1q PF00386.21 OWF51340.1 - 1e-20 74.2 0.6 2.2e-20 73.1 0.1 1.9 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF51340.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 BclA C-terminal domain Gly_transf_sug PF04488.15 OWF51341.1 - 1.6e-10 41.5 2.2 3e-09 37.4 0.8 2.8 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Nucleotid_trans PF03407.16 OWF51341.1 - 1.7e-05 24.9 0.7 3e-05 24.1 0.7 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Caps_synth PF05704.12 OWF51341.1 - 2.7e-05 23.7 0.1 5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 OWF51341.1 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain UPF0060 PF02694.15 OWF51341.1 - 0.064 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family 7tm_1 PF00001.21 OWF51342.1 - 1.3e-18 67.3 12.8 1.3e-18 67.3 12.8 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) OGFr_N PF04664.13 OWF51342.1 - 0.022 14.3 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region Srg PF02118.21 OWF51342.1 - 0.34 10.5 27.1 0.11 12.1 18.6 2.9 1 1 0 2 2 2 0 Srg family chemoreceptor CopD PF05425.13 OWF51342.1 - 0.43 11.0 3.6 0.75 10.2 0.1 2.5 2 0 0 2 2 2 0 Copper resistance protein D Serpentine_r_xa PF03383.15 OWF51342.1 - 4.9 7.1 15.3 0.05 13.6 3.4 2.8 3 1 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa zf-C3HC4_3 PF13920.6 OWF51344.1 - 2.6e-11 43.2 19.3 2.6e-11 43.2 19.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF51344.1 - 8.5e-05 22.3 17.6 8.5e-05 22.3 17.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF51344.1 - 0.002 18.5 15.8 0.002 18.5 15.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF51344.1 - 0.0034 17.3 15.7 0.0034 17.3 15.7 2.6 2 1 1 3 3 3 1 zinc-RING finger domain HATPase_c_3 PF13589.6 OWF51344.1 - 0.075 12.9 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PMC2NT PF08066.12 OWF51344.1 - 0.81 10.4 3.3 0.65 10.7 0.5 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain EF-G-binding_N PF07299.11 OWF51344.1 - 2.5 8.7 6.4 2.8 8.5 1.6 2.6 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal HSA PF07529.13 OWF51344.1 - 3.9 7.9 9.7 9.4 6.6 0.3 2.7 2 0 0 2 2 2 0 HSA MutS_III PF05192.18 OWF51344.1 - 5.1 7.3 12.0 33 4.6 0.1 2.5 2 0 0 2 2 2 0 MutS domain III N_BRCA1_IG PF16158.5 OWF51345.1 - 1.5e-29 102.7 0.1 4.8e-29 101.1 0.1 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 OWF51345.1 - 2.2e-09 37.1 0.0 9.9e-09 35.0 0.0 2.3 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 OWF51345.1 - 9.9e-08 31.7 10.6 1.9e-07 30.8 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 OWF51345.1 - 0.78 10.1 11.4 1.7 9.0 11.4 1.5 1 0 0 1 1 1 0 C1 domain HAP1_N PF04849.13 OWF51346.1 - 4.1e-98 328.4 40.2 6.7e-98 327.7 40.2 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 OWF51346.1 - 6e-30 104.6 10.3 6e-30 104.6 10.3 4.2 2 2 1 4 4 4 1 Kinesin associated protein Rootletin PF15035.6 OWF51346.1 - 0.002 18.2 41.0 0.0043 17.1 5.1 2.8 3 0 0 3 3 3 2 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 OWF51346.1 - 0.023 14.8 24.9 0.36 11.0 1.9 4.4 3 1 0 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 OWF51346.1 - 1.1 9.2 14.6 1.8 8.5 0.1 3.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Shugoshin_N PF07558.11 OWF51346.1 - 8.8 6.3 12.0 1.1 9.1 0.4 3.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region HEPN PF05168.14 OWF51347.1 - 6e-16 58.6 0.1 9.2e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 HEPN domain Patched PF02460.18 OWF51348.1 - 1.5e-138 463.2 12.5 1.9e-138 462.9 12.5 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF51348.1 - 2.3e-34 118.4 17.9 8.4e-34 116.6 2.6 2.9 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OWF51348.1 - 1.1 6.8 17.2 1.8 6.1 17.2 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Patched PF02460.18 OWF51349.1 - 1.2e-134 450.4 14.9 1.5e-134 450.0 14.9 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF51349.1 - 9.1e-35 119.8 5.7 9.1e-35 119.8 5.7 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OWF51349.1 - 0.013 13.2 13.6 0.026 12.2 13.6 1.4 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family LRR_6 PF13516.6 OWF51351.1 - 3.1e-20 70.5 13.3 1.4e-06 27.9 0.1 7.3 7 0 0 7 7 7 4 Leucine Rich repeat EF-hand_1 PF00036.32 OWF51351.1 - 9e-10 37.4 3.9 0.00011 21.5 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF51351.1 - 1.7e-07 31.6 1.3 4.5e-07 30.2 1.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF51351.1 - 2.8e-07 29.9 2.6 0.0011 18.7 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain LRR_1 PF00560.33 OWF51351.1 - 4.5e-07 29.5 1.5 2.1 9.2 0.0 6.3 5 0 0 5 5 5 1 Leucine Rich Repeat EF-hand_8 PF13833.6 OWF51351.1 - 2.6e-05 24.0 4.1 8.6e-05 22.3 1.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF51351.1 - 0.00064 19.1 5.7 0.19 11.3 0.4 2.7 2 0 0 2 2 2 2 EF hand LRR_8 PF13855.6 OWF51351.1 - 0.026 14.3 12.1 1.5 8.6 0.8 4.6 4 2 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 OWF51351.1 - 0.51 10.8 13.6 1.9 9.0 0.5 4.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) BBS2_Mid PF14783.6 OWF51352.1 - 0.0014 18.6 0.2 4.9 7.2 0.0 4.0 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 OWF51352.1 - 0.0018 18.8 0.5 2.4 8.8 0.0 2.8 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 OWF51352.1 - 0.029 13.4 0.0 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 OWF51352.1 - 0.11 12.7 1.3 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 FG-GAP repeat KH_1 PF00013.29 OWF51353.1 - 0.0019 18.0 0.6 0.0019 18.0 0.6 2.0 2 0 0 2 2 2 1 KH domain KH_8 PF17903.1 OWF51353.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain zf-Tim10_DDP PF02953.15 OWF51354.1 - 2.2e-14 52.8 3.6 3.1e-14 52.3 3.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TALPID3 PF15324.6 OWF51355.1 - 1.1e-27 96.3 14.6 2e-27 95.4 14.6 1.4 1 0 0 1 1 1 1 Hedgehog signalling target EcoRII-C PF09019.11 OWF51356.1 - 0.19 11.8 0.3 55 3.8 0.0 4.3 1 1 3 6 6 6 0 EcoRII C terminal ANAPC10 PF03256.16 OWF51356.1 - 0.5 10.0 3.2 20 4.7 0.9 4.4 1 1 2 4 4 4 0 Anaphase-promoting complex, subunit 10 (APC10) IRF-2BP1_2 PF11261.8 OWF51357.1 - 4.3e-34 115.8 1.1 9.2e-34 114.8 1.1 1.6 1 0 0 1 1 1 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.25 OWF51357.1 - 0.002 18.0 6.8 0.0048 16.7 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF51357.1 - 0.013 15.3 6.0 0.038 13.8 6.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51357.1 - 8.5 6.8 12.2 0.52 10.7 6.7 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 OWF51357.1 - 9.2 6.2 15.4 0.028 14.3 5.4 1.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) 4HBT_2 PF13279.6 OWF51358.1 - 0.0081 16.6 14.3 3.6e+03 -1.6 14.3 4.8 1 1 0 1 1 1 0 Thioesterase-like superfamily TALPID3 PF15324.6 OWF51359.1 - 4.6e-66 223.4 56.2 2e-57 194.8 25.1 2.7 2 1 0 2 2 2 2 Hedgehog signalling target Atg8 PF02991.16 OWF51360.1 - 2e-39 133.9 0.4 2.4e-39 133.7 0.4 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OWF51360.1 - 4.2e-05 23.9 0.2 6.1e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad60-SLD PF11976.8 OWF51360.1 - 0.078 12.8 0.2 1.5 8.7 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like CSN8_PSD8_EIF3K PF10075.9 OWF51361.1 - 1.8e-32 112.3 0.2 2.6e-32 111.8 0.2 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OWF51361.1 - 1.6e-05 24.4 0.8 2.4e-05 23.9 0.8 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF4912 PF16258.5 OWF51361.1 - 0.038 14.2 0.1 4.4 7.5 0.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4912) DUF2465 PF10239.9 OWF51362.1 - 2.7e-117 391.6 0.6 3.2e-117 391.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DUF2313 PF10076.9 OWF51362.1 - 0.072 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) LPP PF04728.13 OWF51363.1 - 1.8e-05 25.0 2.3 10 6.6 0.1 5.7 1 1 6 7 7 7 1 Lipoprotein leucine-zipper S10_plectin PF03501.15 OWF51363.1 - 0.00057 19.9 0.8 30 4.8 0.0 5.6 2 1 2 5 5 5 0 Plectin/S10 domain DUF948 PF06103.11 OWF51363.1 - 0.01 16.1 29.8 2.2 8.6 1.9 4.3 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) COG7 PF10191.9 OWF51363.1 - 0.017 13.4 15.1 1.2 7.3 0.6 4.6 1 1 3 4 4 4 0 Golgi complex component 7 (COG7) Rab3-GTPase_cat PF13890.6 OWF51363.1 - 0.064 12.9 0.6 84 2.8 0.1 4.3 1 1 3 4 4 4 0 Rab3 GTPase-activating protein catalytic subunit PHM7_ext PF12621.8 OWF51363.1 - 0.067 13.4 23.8 5.3 7.3 0.4 5.7 1 1 5 6 6 6 0 Extracellular tail, of 10TM putative phosphate transporter I_LWEQ PF01608.17 OWF51363.1 - 0.36 11.1 1.6 36 4.6 0.5 3.7 1 1 1 2 2 2 0 I/LWEQ domain DUF2935 PF11155.8 OWF51363.1 - 0.44 10.9 7.7 1.5e+02 2.7 7.7 3.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DNA_pol_B_3 PF08408.10 OWF51363.1 - 0.46 10.7 31.0 2 8.6 11.7 3.3 1 1 3 4 4 4 0 DNA polymerase family B viral insert Ank_4 PF13637.6 OWF51364.1 - 3.8e-13 49.6 5.3 1.3e-07 32.1 0.5 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF51364.1 - 1.4e-10 41.2 0.8 2.3e-05 24.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF51364.1 - 2.8e-10 40.7 1.8 1.4e-09 38.4 1.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF51364.1 - 7.1e-10 38.9 2.2 0.00019 21.7 0.9 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OWF51364.1 - 4e-09 36.0 1.4 2.2e-05 24.5 0.3 2.8 3 0 0 3 3 3 2 Ankyrin repeat PIR PF00399.19 OWF51364.1 - 0.00086 18.8 0.8 0.0024 17.4 0.8 1.7 1 0 0 1 1 1 1 Yeast PIR protein repeat Ammonium_transp PF00909.21 OWF51366.1 - 7.4e-116 387.1 28.1 9.5e-116 386.8 28.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family 7tm_6 PF02949.20 OWF51366.1 - 0.58 9.2 3.3 1.1 8.2 3.3 1.4 1 0 0 1 1 1 0 7tm Odorant receptor TED_complement PF07678.14 OWF51367.1 - 1.6e-93 313.2 0.2 2.2e-93 312.7 0.2 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 OWF51367.1 - 2.3e-33 115.5 0.1 5.9e-30 104.5 0.0 2.8 2 0 0 2 2 2 2 Alpha-2-macroglobulin bait region domain A2M_recep PF07677.14 OWF51367.1 - 2.6e-23 82.5 0.7 2.6e-23 82.5 0.7 3.4 3 0 0 3 3 3 1 A-macroglobulin receptor binding domain A2M PF00207.22 OWF51367.1 - 1.8e-20 72.6 0.0 5.3e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG3 PF17791.1 OWF51367.1 - 2.4e-20 72.6 0.0 9.6e-20 70.7 0.0 2.1 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG2 PF01835.19 OWF51367.1 - 9.4e-17 61.3 0.0 1.9e-15 57.1 0.0 2.9 3 0 0 3 3 3 1 MG2 domain MG4 PF17789.1 OWF51367.1 - 4.6e-12 45.9 0.1 1.9e-11 44.0 0.1 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG4 SVA PF05326.11 OWF51367.1 - 2.4e-05 24.3 0.0 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) NTR PF01759.21 OWF51367.1 - 0.024 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 UNC-6/NTR/C345C module SQHop_cyclase_C PF13243.6 OWF51367.1 - 0.032 13.3 0.0 0.086 11.9 0.0 1.7 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain TPMT PF05724.11 OWF51368.1 - 6.6e-37 127.3 0.0 8.7e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 OWF51368.1 - 0.00054 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF51368.1 - 0.027 15.2 0.1 0.29 11.9 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain RNA_pol PF00940.19 OWF51368.1 - 0.04 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase Vps5 PF09325.10 OWF51369.1 - 2.8e-82 275.8 20.5 4e-82 275.3 20.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 OWF51369.1 - 6.4e-23 80.9 0.2 6.4e-23 80.9 0.2 2.6 3 0 0 3 3 3 1 PX domain BAR_3_WASP_bdg PF10456.9 OWF51369.1 - 4.2e-08 33.0 9.8 1.9e-05 24.3 9.5 2.8 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein TMEM108 PF15759.5 OWF51369.1 - 0.0022 17.1 4.2 0.0033 16.5 4.2 1.2 1 0 0 1 1 1 1 TMEM108 family Spc7 PF08317.11 OWF51369.1 - 0.073 11.9 20.1 0.5 9.2 7.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1835 PF08874.10 OWF51369.1 - 0.12 12.5 0.3 0.12 12.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) FUSC PF04632.12 OWF51369.1 - 0.31 9.5 1.6 0.44 9.0 1.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3138 PF11336.8 OWF51369.1 - 1.3 7.5 3.7 0.45 9.1 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) UvrC_HhH_N PF08459.11 OWF51369.1 - 2.3 8.1 5.5 3.4 7.6 0.4 3.2 2 1 0 3 3 3 0 UvrC Helix-hairpin-helix N-terminal Exonuc_VII_L PF02601.15 OWF51369.1 - 8.2 5.9 14.4 1.8 8.1 3.5 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF848 PF05852.11 OWF51369.1 - 8.5 6.5 11.1 1.7 8.8 3.7 2.7 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) L_HMGIC_fpl PF10242.9 OWF51370.1 - 0.0046 17.2 11.5 0.0072 16.5 11.5 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein EI24 PF07264.11 OWF51370.1 - 0.013 15.8 0.5 0.013 15.8 0.5 2.1 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF973 PF06157.11 OWF51370.1 - 1.5 7.8 11.5 0.47 9.4 7.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Lipocalin PF00061.23 OWF51371.1 - 0.0016 18.7 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF51371.1 - 0.045 13.6 1.2 0.068 13.0 0.1 1.7 2 0 0 2 2 2 0 Triabin LGT PF01790.18 OWF51372.1 - 0.032 13.5 4.8 0.06 12.6 4.8 1.4 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase PAP_PilO PF06864.12 OWF51372.1 - 0.13 11.1 0.2 0.22 10.3 0.2 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Mem_trans PF03547.18 OWF51372.1 - 0.21 10.0 3.8 0.52 8.6 3.8 1.6 1 0 0 1 1 1 0 Membrane transport protein Tetraspanin PF00335.20 OWF51372.1 - 0.23 11.1 10.5 0.43 10.3 9.8 1.7 1 1 0 1 1 1 0 Tetraspanin family L_HMGIC_fpl PF10242.9 OWF51372.1 - 0.33 11.1 9.1 0.47 10.6 9.1 1.3 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF2749 PF10907.8 OWF51372.1 - 0.47 10.7 2.7 1 9.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF1129 PF06570.11 OWF51372.1 - 0.48 9.9 5.6 0.15 11.6 2.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Claudin_3 PF06653.11 OWF51372.1 - 0.56 10.1 16.8 1.5 8.8 16.8 1.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like YtxH PF12732.7 OWF51372.1 - 0.63 10.6 0.2 0.63 10.6 0.2 2.2 2 0 0 2 2 2 0 YtxH-like protein DUF2157 PF09925.9 OWF51372.1 - 0.79 9.5 10.4 0.11 12.3 5.5 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) MARVEL PF01284.23 OWF51372.1 - 0.81 9.7 12.7 1.9 8.5 12.8 1.5 1 1 0 1 1 1 0 Membrane-associating domain SUR7 PF06687.12 OWF51372.1 - 1.3 8.6 15.2 0.2 11.3 6.7 2.1 1 1 1 2 2 2 0 SUR7/PalI family Ost5 PF05251.12 OWF51372.1 - 2.8 8.3 15.9 0.13 12.5 3.8 2.5 3 0 0 3 3 2 0 Oligosaccharyltransferase subunit 5 DUF2852 PF11014.8 OWF51372.1 - 3.9 7.6 6.7 7.5 6.7 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) PEX11 PF05648.14 OWF51373.1 - 4.2e-17 62.3 0.1 4.7e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 OWF51374.1 - 5.8e-38 130.6 1.2 6.5e-38 130.4 1.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) LAB_N PF07578.11 OWF51374.1 - 0.047 13.8 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF2781 PF10914.8 OWF51375.1 - 1.7e-12 48.0 4.9 1.7e-12 48.0 4.9 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2781) JTB PF05439.12 OWF51376.1 - 9.8e-19 67.4 2.2 1.6e-18 66.7 2.2 1.3 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) DUF3139 PF11337.8 OWF51376.1 - 0.043 14.5 0.5 11 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Insulin_TMD PF17870.1 OWF51376.1 - 0.14 12.3 6.0 0.14 12.2 0.4 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Cupin_8 PF13621.6 OWF51377.1 - 2.8e-36 125.5 5.7 3.3e-35 122.0 0.8 3.0 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 OWF51377.1 - 0.0001 22.7 0.4 0.00082 19.8 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 OWF51377.1 - 0.054 13.0 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein zf-C2H2_4 PF13894.6 OWF51378.1 - 3.1e-12 46.2 109.3 0.026 15.4 0.7 18.9 19 0 0 19 19 19 8 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF51378.1 - 1.2e-10 40.9 37.8 2.5e-09 36.7 0.2 10.1 11 0 0 11 11 11 3 zinc-finger C2H2-type zf-C2H2 PF00096.26 OWF51378.1 - 1.2e-10 41.2 109.9 0.034 14.6 0.2 16.4 17 0 0 17 17 17 9 Zinc finger, C2H2 type zf-Di19 PF05605.12 OWF51378.1 - 0.0017 18.6 5.7 0.0017 18.6 5.7 9.3 9 3 2 11 11 11 2 Drought induced 19 protein (Di19), zinc-binding zf_Hakai PF18408.1 OWF51378.1 - 0.0034 17.0 7.0 0.049 13.3 0.1 3.6 3 0 0 3 3 3 2 C2H2 Hakai zinc finger domain zf-C2H2_3rep PF18868.1 OWF51378.1 - 0.0072 17.0 0.6 0.0072 17.0 0.6 8.7 3 1 6 9 9 9 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 OWF51378.1 - 0.041 13.9 0.1 0.041 13.9 0.1 13.7 15 2 0 15 15 15 0 C2H2-type zinc finger FATC PF02260.20 OWF51378.1 - 0.096 12.5 2.3 22 5.0 0.1 3.8 3 0 0 3 3 3 0 FATC domain zf-H2C2_2 PF13465.6 OWF51378.1 - 0.28 11.7 0.1 0.26 11.8 0.2 15.6 17 0 0 17 17 17 0 Zinc-finger double domain FERM_C PF09380.10 OWF51379.1 - 1.1e-23 83.4 0.6 2.3e-23 82.4 0.6 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 OWF51379.1 - 5.7e-19 68.7 0.3 2.3e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 OWF51379.1 - 1.6e-15 56.8 0.1 3.3e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain Ribosomal_S19 PF00203.21 OWF51380.1 - 1.5e-21 76.0 0.5 2.6e-21 75.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 OWF51380.1 - 0.046 13.8 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Neur_chan_memb PF02932.16 OWF51381.1 - 0.00024 21.2 0.1 0.00024 21.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 7tm_6 PF02949.20 OWF51381.1 - 0.036 13.2 0.1 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 7tm Odorant receptor IFRD PF05004.13 OWF51381.1 - 0.08 12.0 0.4 0.094 11.8 0.4 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Ras PF00071.22 OWF51382.1 - 2.5e-34 118.2 0.1 3e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF51382.1 - 8.2e-16 58.3 0.0 1.3e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF51382.1 - 4.9e-06 26.1 0.1 8e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF51382.1 - 0.00088 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OWF51382.1 - 0.0042 17.1 0.1 0.0067 16.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OWF51382.1 - 0.0054 16.8 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF51382.1 - 0.0097 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OWF51382.1 - 0.02 14.7 0.3 0.29 10.9 0.3 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DAO PF01266.24 OWF51383.1 - 4.1e-55 187.8 0.0 6.3e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OWF51383.1 - 3.1e-41 140.2 0.1 5.8e-41 139.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 OWF51383.1 - 3e-12 46.8 0.6 7.3e-12 45.6 0.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 OWF51383.1 - 2.3e-08 33.5 2.0 5.2e-05 22.5 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain EF-hand_1 PF00036.32 OWF51383.1 - 3.2e-08 32.6 0.2 0.0088 15.5 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF51383.1 - 3e-07 30.2 0.1 1.6e-06 27.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF51383.1 - 1.1e-06 28.1 0.6 0.0006 19.5 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain FAD_oxidored PF12831.7 OWF51383.1 - 1.6e-05 24.5 1.3 7.4e-05 22.3 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OWF51383.1 - 0.00021 20.5 0.3 0.0083 15.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A EF-hand_9 PF14658.6 OWF51383.1 - 0.0005 20.4 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain FAD_binding_3 PF01494.19 OWF51383.1 - 0.0018 17.6 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OWF51383.1 - 0.0074 15.5 1.1 0.052 12.8 1.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF51383.1 - 0.012 14.6 0.7 1.9 7.5 0.3 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 OWF51383.1 - 0.036 12.8 0.3 0.06 12.0 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 OWF51383.1 - 0.055 13.7 0.4 0.26 11.5 0.3 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MGS PF02142.22 OWF51383.1 - 0.087 13.0 0.0 26 5.1 0.0 2.8 3 0 0 3 3 2 0 MGS-like domain EF-hand_4 PF12763.7 OWF51383.1 - 0.12 12.4 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Pyr_redox_3 PF13738.6 OWF51383.1 - 0.14 11.3 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF51383.1 - 0.27 11.8 1.7 0.58 10.8 0.5 2.2 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 OWF51384.1 - 1.3e-61 208.5 0.0 1.6e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme YrbL-PhoP_reg PF10707.9 OWF51384.1 - 0.013 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AMP-binding PF00501.28 OWF51385.1 - 1.9e-54 184.9 0.0 3.1e-29 101.8 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme Npa1 PF11707.8 OWF51385.1 - 0.0085 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal AMP-binding PF00501.28 OWF51386.1 - 1.6e-65 221.4 0.0 1.9e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme YrbL-PhoP_reg PF10707.9 OWF51386.1 - 0.0056 16.2 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Ion_trans PF00520.31 OWF51387.1 - 1.1e-30 106.7 12.7 1.5e-30 106.2 12.7 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 OWF51387.1 - 1.9e-19 69.9 0.0 4.4e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain Ion_trans_2 PF07885.16 OWF51387.1 - 4e-10 39.5 0.3 4e-10 39.5 0.3 2.2 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 OWF51387.1 - 3.5e-09 36.6 0.0 1.2e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_3 PF08447.12 OWF51387.1 - 3e-06 27.4 0.0 7.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OWF51387.1 - 6.4e-05 22.9 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OWF51387.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold NPV_P10 PF05531.12 OWF51387.1 - 0.05 14.1 1.2 0.1 13.1 0.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 OWF51387.1 - 2.1 8.7 9.7 0.17 12.2 0.4 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IRK PF01007.20 OWF51387.1 - 2.3 8.1 5.1 8.5 6.2 5.1 1.9 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Osmo_CC PF08946.10 OWF51387.1 - 3 8.2 5.3 0.74 10.1 0.2 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Kelch_1 PF01344.25 OWF51388.1 - 1.6e-68 226.1 12.2 1.3e-12 47.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OWF51388.1 - 4.6e-28 96.5 5.9 1.1e-06 28.7 0.1 5.9 3 1 3 6 6 6 5 Kelch motif BTB PF00651.31 OWF51388.1 - 8.2e-28 96.9 0.0 1.7e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF51388.1 - 2.3e-27 95.1 0.2 4.6e-27 94.1 0.1 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 OWF51388.1 - 1.8e-24 84.7 6.0 4e-05 23.4 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OWF51388.1 - 3.1e-21 75.2 6.2 0.00028 21.1 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OWF51388.1 - 2.8e-20 72.1 4.7 6.4e-05 22.9 0.0 5.4 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF51388.1 - 9.5e-13 47.8 5.7 0.0093 15.9 0.1 5.5 5 0 0 5 5 5 3 Kelch motif Skp1_POZ PF03931.15 OWF51388.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF1269 PF06897.12 OWF51389.1 - 0.00072 19.8 5.3 1.7 9.0 0.2 4.0 1 1 2 3 3 3 3 Protein of unknown function (DUF1269) Glyco_hydro_42C PF08533.10 OWF51389.1 - 0.0021 17.7 3.4 21 4.9 0.0 4.8 1 1 4 6 6 6 1 Beta-galactosidase C-terminal domain PurS PF02700.14 OWF51389.1 - 0.024 14.8 9.7 1.2 9.3 0.7 3.6 1 1 4 5 5 5 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF3201 PF11447.8 OWF51389.1 - 0.24 10.9 16.5 0.79 9.3 1.3 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF3201) DUF4504 PF14953.6 OWF51389.1 - 0.45 9.9 5.9 5.5 6.3 0.3 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4504) EXOSC1 PF10447.9 OWF51389.1 - 7.2 7.3 18.7 9.1 6.9 4.7 3.5 1 1 3 4 4 4 0 Exosome component EXOSC1/CSL4 DUF1667 PF07892.11 OWF51389.1 - 8.8 6.5 12.4 20 5.3 0.5 4.5 1 1 5 6 6 6 0 Protein of unknown function (DUF1667) EPTP PF03736.17 OWF51390.1 - 8.6e-80 262.5 16.5 6.8e-15 54.8 0.3 7.3 7 0 0 7 7 7 7 EPTP domain Laminin_G_2 PF02210.24 OWF51390.1 - 0.00031 21.3 0.0 0.00079 20.0 0.0 1.7 1 0 0 1 1 1 1 Laminin G domain WYL_2 PF10902.8 OWF51390.1 - 0.23 11.8 3.8 5.9 7.3 0.2 3.0 2 1 1 3 3 3 0 WYL_2, Sm-like SH3 beta-barrel fold DUF2818 PF10993.8 OWF51390.1 - 0.88 10.2 10.1 1.7 9.2 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2818) VWA PF00092.28 OWF51391.1 - 1.1e-19 71.4 0.5 1.3e-19 71.1 0.5 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1943 PF09172.11 OWF51392.1 - 2.4e-05 23.7 4.6 6e-05 22.4 4.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1943) Attacin_C PF03769.15 OWF51392.1 - 0.002 18.3 7.6 0.047 13.9 2.1 2.1 1 1 1 2 2 2 2 Attacin, C-terminal region Porin_3 PF01459.22 OWF51392.1 - 0.043 13.3 7.1 0.045 13.2 7.1 1.0 1 0 0 1 1 1 0 Eukaryotic porin DUF481 PF04338.12 OWF51392.1 - 0.26 11.3 7.1 0.3 11.1 6.3 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF481 DUF1943 PF09172.11 OWF51393.1 - 0.06 12.6 0.1 0.06 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3194 PF11419.8 OWF51393.1 - 1.8 9.0 12.0 4.3 7.8 5.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3194) DUF481 PF04338.12 OWF51393.1 - 2.9 7.8 8.3 3.1 7.8 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF481 Collagen PF01391.18 OWF51394.1 - 1.2e-86 284.4 400.6 4.1e-09 36.0 27.4 16.5 5 4 9 14 14 14 14 Collagen triple helix repeat (20 copies) Endostatin PF06482.11 OWF51394.1 - 1.1e-73 248.5 0.0 6e-62 209.9 0.1 2.1 1 1 1 2 2 2 2 Collagenase NC10 and Endostatin Laminin_G_3 PF13385.6 OWF51394.1 - 0.00015 21.9 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1554 PF07588.11 OWF51394.1 - 0.0016 18.2 0.3 0.0055 16.5 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1554) Cupin_8 PF13621.6 OWF51395.1 - 6.3e-44 150.6 0.1 7.8e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OWF51395.1 - 1.5e-08 34.5 0.2 2.1e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OWF51395.1 - 0.038 14.4 0.1 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase Peptidase_C14 PF00656.22 OWF51397.1 - 5.1e-40 138.0 0.0 7.9e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DED PF01335.21 OWF51397.1 - 6.4e-33 112.9 11.2 6.3e-18 64.9 2.1 2.4 2 0 0 2 2 2 2 Death effector domain Death PF00531.22 OWF51397.1 - 7.1e-05 22.9 0.1 0.028 14.6 0.0 3.4 3 0 0 3 3 3 1 Death domain Ras PF00071.22 OWF51398.1 - 1.4e-34 119.1 0.0 1.7e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF51398.1 - 2.8e-16 59.8 0.0 3.7e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF51398.1 - 1.5e-07 31.0 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF51398.1 - 0.00017 21.2 0.2 0.0026 17.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF51398.1 - 0.00022 21.3 0.0 0.0003 20.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF51398.1 - 0.012 15.9 0.2 0.17 12.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 OWF51398.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF51398.1 - 0.042 13.8 0.0 0.94 9.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 OWF51398.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ATPase_2 PF01637.18 OWF51398.1 - 0.07 13.0 0.1 0.078 12.9 0.1 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea XFP_N PF09364.10 OWF51398.1 - 0.086 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Lectin_C PF00059.21 OWF51399.1 - 1.3e-07 32.3 0.2 1.6e-07 32.0 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 OWF51400.1 - 1.8e-12 47.9 0.9 2.3e-12 47.6 0.9 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF51400.1 - 5.8e-05 22.8 0.1 7e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like EF-hand_7 PF13499.6 OWF51401.1 - 1.3e-23 83.2 3.9 2.9e-16 59.7 0.3 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF51401.1 - 5.9e-22 75.5 6.3 6.2e-07 28.5 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OWF51401.1 - 4.2e-20 70.3 1.9 2.7e-07 29.8 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF51401.1 - 9.9e-20 68.7 3.8 8.4e-06 25.3 0.0 4.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 OWF51401.1 - 7.8e-14 51.3 7.1 2.2e-06 27.4 2.2 3.8 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF51401.1 - 5.7e-08 33.1 0.4 0.0012 19.1 0.0 4.0 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF51401.1 - 0.0021 18.0 1.8 7.3 6.6 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_2 PF09068.11 OWF51401.1 - 0.13 12.4 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 OWF51401.1 - 0.55 10.5 2.5 16 5.8 0.1 2.5 2 1 0 2 2 2 0 Dockerin type I domain DUF4994 PF16385.5 OWF51402.1 - 0.0086 16.0 0.2 1.5 8.7 0.0 2.6 1 1 2 3 3 3 2 Domain of unknown function DUF3088 PF11287.8 OWF51402.1 - 0.0091 15.8 1.0 10 5.9 0.1 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3088) PUMA PF15826.5 OWF51402.1 - 0.17 12.1 1.3 3.4 7.8 0.3 1.9 1 1 1 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Mucin-like PF16058.5 OWF51402.1 - 0.2 11.7 7.0 0.27 11.3 7.0 1.3 1 0 0 1 1 1 0 Mucin-like PTN13_u3 PF16599.5 OWF51403.1 - 0.084 12.9 1.4 0.11 12.6 1.4 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ FGGY_N PF00370.21 OWF51404.1 - 1.4e-20 73.9 0.0 2.6e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OWF51404.1 - 8.1e-15 55.1 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain 7tm_1 PF00001.21 OWF51405.1 - 9.6e-46 156.2 26.2 1.2e-45 155.9 26.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF51405.1 - 1e-10 41.4 25.7 1.5e-10 40.9 25.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx YHYH PF14240.6 OWF51406.1 - 2e-17 63.8 4.2 3.2e-14 53.3 0.2 2.9 2 1 1 3 3 3 2 YHYH protein FXa_inhibition PF14670.6 OWF51406.1 - 0.1 12.9 0.8 0.27 11.6 0.8 1.7 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site F-box-like PF12937.7 OWF51407.1 - 4e-07 29.8 0.4 9e-07 28.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF51407.1 - 0.0052 16.6 0.5 0.014 15.2 0.5 1.8 1 0 0 1 1 1 1 F-box domain zf-C2H2 PF00096.26 OWF51407.1 - 0.034 14.6 0.9 0.13 12.7 0.9 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type LRR_4 PF12799.7 OWF51407.1 - 0.052 14.0 0.1 0.59 10.6 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Reprolysin_5 PF13688.6 OWF51408.1 - 3.2e-21 76.4 6.4 3.2e-21 76.4 6.4 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OWF51408.1 - 4e-16 59.5 3.7 2.7e-15 56.8 3.7 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 OWF51408.1 - 1.4e-09 38.2 17.3 1.4e-09 38.2 17.3 3.6 3 1 0 3 3 3 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin_3 PF13582.6 OWF51408.1 - 1.8e-06 28.5 0.0 5.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 OWF51408.1 - 0.00091 19.2 0.6 0.016 15.1 0.4 2.6 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Fez1 PF06818.15 OWF51409.1 - 2.4e-22 80.3 17.5 2.4e-22 80.3 17.5 2.9 1 1 0 2 2 2 2 Fez1 PKcGMP_CC PF16808.5 OWF51409.1 - 0.002 17.9 16.5 0.0069 16.2 0.4 4.2 2 1 2 4 4 4 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3450 PF11932.8 OWF51409.1 - 0.79 9.0 37.0 0.15 11.4 14.4 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3450) TatD_DNase PF01026.21 OWF51410.1 - 6e-28 97.9 0.0 1.2e-27 97.0 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase THEG PF14912.6 OWF51412.1 - 6.5e-44 148.2 12.6 4.2e-12 46.3 0.5 6.0 4 2 2 6 6 6 6 Testicular haploid expressed repeat Nop16 PF09420.10 OWF51413.1 - 6.9e-23 81.8 10.7 5.3e-16 59.3 0.6 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 DUF3086 PF11285.8 OWF51413.1 - 0.42 9.7 2.8 0.77 8.8 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) HIG_1_N PF04588.13 OWF51414.1 - 0.00076 19.7 0.8 0.0012 19.0 0.8 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region FYRN PF05964.14 OWF51415.1 - 7.5e-22 76.9 0.2 1.2e-21 76.2 0.2 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 OWF51415.1 - 2.4e-17 62.9 0.0 5.6e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus Viral_P18 PF04521.13 OWF51416.1 - 4.5 7.1 7.1 3.8 7.3 1.6 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Baculo_p24 PF05073.12 OWF51417.1 - 0.003 17.3 0.0 0.0088 15.9 0.0 1.7 1 0 0 1 1 1 1 Baculovirus P24 capsid protein IFT81_CH PF18383.1 OWF51417.1 - 0.069 13.4 0.0 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 Intraflagellar transport 81 calponin homology domain DUF4646 PF15496.6 OWF51419.1 - 2.9e-13 50.5 22.1 1.6 9.3 0.1 10.9 1 1 9 10 10 10 9 Domain of unknown function (DUF4646) aGPT-Pplase2 PF18724.1 OWF51419.1 - 0.0084 15.9 31.4 7.8 6.2 0.3 8.5 1 1 8 9 9 9 5 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 AsnC_trans_reg2 PF17805.1 OWF51419.1 - 0.2 11.9 12.9 15 5.8 0.1 5.6 2 1 5 7 7 7 0 AsnC-like ligand binding domain Adeno_IVa2 PF02456.15 OWF51419.1 - 0.84 8.4 13.0 3.3 6.4 1.2 3.6 1 1 3 4 4 4 0 Adenovirus IVa2 protein DUF294 PF03445.13 OWF51419.1 - 6.5 6.6 8.6 1.5e+02 2.1 0.1 5.3 2 1 4 7 7 7 0 Putative nucleotidyltransferase DUF294 Amelogenin PF02948.15 OWF51422.1 - 0.0025 18.5 41.6 0.03 15.0 17.3 2.3 1 1 1 2 2 2 2 Amelogenin DUF4573 PF15140.6 OWF51422.1 - 0.0076 16.1 14.8 0.1 12.4 13.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) YafQ_toxin PF15738.5 OWF51422.1 - 2.1 8.7 15.9 20 5.6 0.3 5.6 1 1 5 6 6 6 0 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF3405 PF11885.8 OWF51422.1 - 6.5 5.2 15.9 9 4.8 2.7 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3405) PI-PLC-X PF00388.19 OWF51423.1 - 5.5e-60 201.2 0.0 1.5e-59 199.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OWF51423.1 - 1.9e-30 105.5 0.1 1.9e-30 105.5 0.1 3.2 3 0 0 3 3 2 1 Phosphatidylinositol-specific phospholipase C, Y domain RasGEF PF00617.19 OWF51423.1 - 1.3e-25 90.6 0.0 4.8e-25 88.8 0.0 2.1 1 0 0 1 1 1 1 RasGEF domain RA PF00788.23 OWF51423.1 - 1.5e-18 67.2 1.4 9.2e-10 39.0 0.0 3.8 4 0 0 4 4 3 2 Ras association (RalGDS/AF-6) domain FERM_M PF00373.18 OWF51423.1 - 3.6e-10 40.3 0.0 3.6e-10 40.3 0.0 3.8 3 0 0 3 3 2 1 FERM central domain Ank_4 PF13637.6 OWF51423.1 - 4.2e-10 40.0 0.0 7.3e-08 32.8 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) C2 PF00168.30 OWF51423.1 - 5.3e-10 39.5 0.0 1.8e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain Ank_3 PF13606.6 OWF51423.1 - 1.3e-07 31.3 0.2 0.34 11.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OWF51423.1 - 1.2e-06 29.0 0.1 2.8e-05 24.6 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF51423.1 - 1.8e-06 28.1 0.0 0.00026 21.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) EF-hand_like PF09279.11 OWF51423.1 - 3e-05 24.4 0.0 3e-05 24.4 0.0 2.9 2 0 0 2 2 1 1 Phosphoinositide-specific phospholipase C, efhand-like TFIIA PF03153.13 OWF51423.1 - 5.7e-05 23.3 27.8 5.7e-05 23.3 27.8 4.2 6 0 0 6 6 3 1 Transcription factor IIA, alpha/beta subunit Ank PF00023.30 OWF51423.1 - 0.00082 19.7 0.3 5.8 7.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Spt20 PF12090.8 OWF51423.1 - 0.0011 18.7 30.9 0.0011 18.7 30.9 3.7 4 0 0 4 4 4 1 Spt20 family Mem_trans PF03547.18 OWF51423.1 - 0.25 9.7 1.9 0.74 8.1 1.9 1.8 1 0 0 1 1 1 0 Membrane transport protein DUF4407 PF14362.6 OWF51423.1 - 0.76 9.1 8.0 2 7.7 8.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mob_synth_C PF06463.13 OWF51423.1 - 1.4 8.8 6.1 0.7 9.8 0.0 2.7 2 0 0 2 2 1 0 Molybdenum Cofactor Synthesis C DUF4175 PF13779.6 OWF51423.1 - 3.6 5.4 24.8 6 4.7 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) V_ATPase_I PF01496.19 OWF51423.1 - 3.8 5.3 9.2 8.6 4.1 9.2 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM51 PF15345.6 OWF51423.1 - 4.4 7.1 18.7 18 5.1 18.7 2.0 1 0 0 1 1 1 0 Transmembrane protein 51 Podoplanin PF05808.11 OWF51424.1 - 0.0046 17.1 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 Podoplanin MtrF PF09472.10 OWF51424.1 - 0.055 12.9 0.4 0.096 12.1 0.4 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) An_peroxidase PF03098.15 OWF51425.1 - 3e-174 580.5 0.0 2.3e-173 577.6 0.0 1.9 2 0 0 2 2 2 2 Animal haem peroxidase Methyltransf_31 PF13847.6 OWF51426.1 - 9e-30 103.5 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF51426.1 - 1e-16 61.4 0.0 1.9e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF51426.1 - 4.9e-15 56.0 0.0 9.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF51426.1 - 7e-14 51.7 0.0 2.7e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF51426.1 - 3.5e-10 40.0 0.0 5.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF51426.1 - 7e-10 39.5 0.0 1.4e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF51426.1 - 2.7e-05 24.0 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 OWF51426.1 - 0.0043 16.5 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 OWF51426.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2670 PF10875.8 OWF51426.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) TehB PF03848.14 OWF51426.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Laminin_G_3 PF13385.6 OWF51427.1 - 0.00026 21.1 2.0 0.00026 21.1 2.0 1.8 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Neur_chan_LBD PF02931.23 OWF51428.1 - 6.7e-15 55.1 0.0 8.9e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51428.1 - 7.2e-13 49.1 4.3 9.2e-13 48.8 4.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF5336 PF17270.2 OWF51428.1 - 0.086 12.5 1.7 0.15 11.7 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) RNase_T PF00929.24 OWF51430.1 - 1.9e-15 57.8 0.8 9.2e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OWF51430.1 - 0.00094 18.9 0.0 0.0025 17.6 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease MDM1 PF15501.6 OWF51431.1 - 7.3e-93 312.6 50.3 2.7e-72 244.7 18.8 3.2 1 1 2 3 3 3 3 Nuclear protein MDM1 tRNA_m1G_MT PF01746.21 OWF51432.1 - 1e-07 31.8 0.1 2.4e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DNTTIP1_dimer PF18192.1 OWF51433.1 - 0.12 12.8 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain IFN-gamma PF00714.17 OWF51434.1 - 0.051 13.4 1.2 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 Interferon gamma OppC_N PF12911.7 OWF51434.1 - 0.081 12.9 0.3 0.081 12.9 0.3 3.9 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C LRAT PF04970.13 OWF51435.1 - 6.2e-21 75.0 2.4 3.3e-13 50.0 0.4 2.1 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF51435.1 - 0.018 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family Calici_PP_N PF08405.11 OWF51435.1 - 0.034 13.0 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal LRAT PF04970.13 OWF51436.1 - 1.6e-19 70.5 1.1 5.8e-12 46.0 0.1 2.3 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF51436.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family Calici_PP_N PF08405.11 OWF51436.1 - 0.032 13.1 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal Cep57_CLD_2 PF14197.6 OWF51437.1 - 0.024 14.7 12.0 0.024 14.7 12.0 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Sas6_CC PF18594.1 OWF51437.1 - 0.12 12.2 6.5 1.2 8.9 1.5 3.0 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain FlaC_arch PF05377.11 OWF51437.1 - 0.29 11.5 0.2 0.29 11.5 0.2 4.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 OWF51437.1 - 0.45 10.8 15.4 0.47 10.7 1.8 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 OWF51437.1 - 0.93 8.3 32.9 0.032 13.1 19.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein TSC22 PF01166.18 OWF51437.1 - 1.3 9.4 15.4 2.8 8.3 2.8 4.1 1 1 2 3 3 3 0 TSC-22/dip/bun family HAP1_N PF04849.13 OWF51437.1 - 3 7.0 27.4 12 5.0 27.4 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region UPF0242 PF06785.11 OWF51437.1 - 4 7.5 28.3 33 4.5 28.3 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 OWF51437.1 - 8.5 6.4 14.3 2.7 8.1 5.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 OWF51437.1 - 8.5 5.4 26.4 0.0094 15.1 13.3 2.1 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_M14 PF00246.24 OWF51438.1 - 1.7e-37 129.8 0.0 2.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Ion_trans_2 PF07885.16 OWF51439.1 - 9.2e-34 115.3 20.8 4.7e-17 61.7 6.5 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF51439.1 - 3.6e-09 36.2 8.8 5.1e-06 25.9 0.6 2.4 2 1 0 2 2 2 2 Ion transport protein IRK PF01007.20 OWF51439.1 - 0.023 14.5 5.4 0.06 13.2 0.2 3.0 2 2 1 3 3 3 0 Inward rectifier potassium channel transmembrane domain Lig_chan PF00060.26 OWF51439.1 - 0.053 13.4 3.9 1.1 9.1 0.6 2.3 1 1 0 2 2 2 0 Ligand-gated ion channel HutP PF09021.11 OWF51439.1 - 0.073 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 HutP MacB_PCD PF12704.7 OWF51439.1 - 0.18 12.2 3.0 9.3 6.5 0.0 2.2 2 0 0 2 2 2 0 MacB-like periplasmic core domain GRP PF07172.11 OWF51439.1 - 0.21 12.3 0.4 38 5.1 0.1 2.5 2 0 0 2 2 2 0 Glycine rich protein family Ninjurin PF04923.12 OWF51439.1 - 0.23 11.4 2.7 25 4.9 0.1 3.2 2 1 1 3 3 3 0 Ninjurin DUF4064 PF13273.6 OWF51439.1 - 0.47 10.8 8.5 4.7 7.5 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4271 PF14093.6 OWF51439.1 - 0.52 10.2 8.0 4.8 7.0 0.6 3.4 1 1 0 3 3 3 0 Domain of unknown function (DUF4271) Frizzled PF01534.17 OWF51439.1 - 1.6 7.7 7.3 0.13 11.3 0.2 2.3 2 2 1 3 3 3 0 Frizzled/Smoothened family membrane region DUF5565 PF17720.1 OWF51440.1 - 0.038 12.8 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) MDH PF02315.16 OWF51441.1 - 0.00088 19.3 0.3 0.3 11.2 0.3 2.5 2 0 0 2 2 2 2 Methanol dehydrogenase beta subunit Rap_GAP PF02145.15 OWF51442.1 - 2.1e-45 154.6 0.0 9.7e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 Rap/ran-GAP SERTA PF06031.13 OWF51443.1 - 3.2e-12 45.9 0.9 8.1e-12 44.6 0.7 1.8 2 0 0 2 2 2 1 SERTA motif FEZ PF07763.13 OWF51444.1 - 7.7e-88 294.3 7.9 1.1e-87 293.8 7.9 1.2 1 0 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 OWF51444.1 - 0.00028 21.0 2.8 0.0017 18.5 2.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) DUF4727 PF15856.5 OWF51444.1 - 0.044 13.4 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) RRM_1 PF00076.22 OWF51445.1 - 1.4e-30 104.9 0.1 1.5e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF51445.1 - 7.1e-05 22.8 0.3 0.00044 20.3 0.1 2.1 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 OWF51445.1 - 0.016 14.8 0.0 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OWF51445.1 - 0.053 13.5 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Rtf2 PF04641.12 OWF51445.1 - 0.98 8.7 9.0 1.4 8.2 9.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF5427 PF10310.9 OWF51445.1 - 5.8 5.8 15.0 7.6 5.4 15.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SNF2_N PF00176.23 OWF51446.1 - 3.3e-66 223.4 0.4 3.3e-66 223.4 0.4 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 OWF51446.1 - 1.1e-47 161.8 25.7 1.1e-47 161.8 25.7 4.3 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 OWF51446.1 - 4e-18 65.8 0.0 1.5e-17 63.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF51446.1 - 6.5e-08 32.8 3.5 1.7e-05 24.9 0.0 3.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OWF51446.1 - 0.00017 20.9 0.0 0.00017 20.9 0.0 3.8 5 1 0 5 5 5 1 Class II histone deacetylase complex subunits 2 and 3 ChaC PF04752.12 OWF51447.1 - 1.7e-54 184.6 0.1 2.3e-54 184.1 0.1 1.2 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 OWF51447.1 - 0.006 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like adh_short_C2 PF13561.6 OWF51448.1 - 0.2 11.1 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF51449.1 - 7.3e-30 103.9 0.0 1.5e-28 99.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF51449.1 - 4.4e-21 75.5 0.0 1.2e-20 74.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF51449.1 - 4.9e-10 39.6 0.0 7.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF51449.1 - 0.0064 16.0 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OWF51449.1 - 0.037 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OWF51449.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 OWF51449.1 - 0.096 12.0 0.0 0.44 9.9 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) CAMP_factor PF07373.11 OWF51449.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 CAMP factor (Cfa) Orexin PF02072.15 OWF51450.1 - 0.042 13.8 1.9 4.2 7.3 0.2 3.5 1 1 1 2 2 2 0 Prepro-orexin CLPTM1 PF05602.12 OWF51451.1 - 2.2e-149 498.1 5.3 2.7e-149 497.9 5.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OWF51451.1 - 0.00062 19.5 1.4 0.62 9.9 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat Menin PF05053.13 OWF51452.1 - 1.4e-219 730.9 1.5 4.2e-217 722.7 1.5 2.0 1 1 0 1 1 1 1 Menin Vps39_1 PF10366.9 OWF51452.1 - 0.25 11.6 2.3 1.1 9.6 0.1 2.8 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Seipin PF06775.14 OWF51453.1 - 1.8e-42 145.7 0.0 2.6e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Dicty_CAR PF05462.11 OWF51453.1 - 0.056 12.6 3.4 0.039 13.1 0.9 1.8 1 1 0 2 2 2 0 Slime mold cyclic AMP receptor PAP_central PF04928.17 OWF51454.1 - 1.4e-112 374.7 0.0 2e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OWF51454.1 - 6.3e-27 94.3 4.2 5.7e-16 58.6 0.2 2.5 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OWF51454.1 - 2.3e-12 47.1 0.4 6.3e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 OWF51454.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Peptidase_M28 PF04389.17 OWF51456.1 - 3.3e-38 131.4 0.0 4.8e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SRF-TF PF00319.18 OWF51457.1 - 8.5e-21 73.2 0.1 1.4e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF971 PF06155.12 OWF51458.1 - 1.1e-10 42.0 0.3 5.2e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF971) dCache_1 PF02743.18 OWF51459.1 - 4.2e-20 72.6 5.0 9.1e-09 35.5 0.2 3.3 3 0 0 3 3 3 3 Cache domain VWA_2 PF13519.6 OWF51459.1 - 2.3e-14 53.9 0.2 7.7e-14 52.2 0.2 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_N PF08399.11 OWF51459.1 - 3.1e-13 50.3 0.4 3e-05 24.5 0.0 2.7 3 0 0 3 3 3 2 VWA N-terminal VWA PF00092.28 OWF51459.1 - 4.7e-13 49.7 1.1 1.1e-12 48.6 1.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF51459.1 - 1.3e-09 38.2 0.1 6e-09 36.0 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 OWF51459.1 - 1.1e-05 25.7 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 OWF51459.1 - 0.01 15.2 0.0 0.032 13.6 0.0 1.7 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein VGCC_alpha2 PF08473.11 OWF51459.1 - 0.019 13.7 0.4 0.1 11.4 0.3 2.1 1 1 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd EphA2_TM PF14575.6 OWF51459.1 - 0.089 13.7 0.0 0.23 12.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 OWF51459.1 - 3.1 7.8 5.3 0.55 10.1 0.8 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 TPR_19 PF14559.6 OWF51460.1 - 1.3e-49 166.6 45.7 8.9e-06 26.1 1.2 17.8 13 4 3 18 18 18 9 Tetratricopeptide repeat TPR_2 PF07719.17 OWF51460.1 - 1e-44 147.0 49.6 0.00091 19.2 0.0 21.6 23 0 0 23 23 22 10 Tetratricopeptide repeat TPR_14 PF13428.6 OWF51460.1 - 8.7e-40 132.0 31.0 0.0039 17.9 0.0 20.7 13 5 7 20 20 20 7 Tetratricopeptide repeat TPR_1 PF00515.28 OWF51460.1 - 1.5e-27 94.2 50.1 0.00042 20.0 0.0 18.3 20 0 0 20 20 18 7 Tetratricopeptide repeat TPR_16 PF13432.6 OWF51460.1 - 1.5e-26 92.8 26.4 1.6e-05 25.4 0.1 16.0 17 3 1 19 19 17 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF51460.1 - 1.2e-25 87.6 20.1 0.00092 19.1 0.0 15.0 14 1 1 15 15 15 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF51460.1 - 5e-24 82.5 33.5 0.017 15.3 0.0 15.9 17 0 0 17 17 14 7 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF51460.1 - 2.8e-20 72.3 42.4 0.0086 16.3 1.7 13.2 11 4 3 15 15 13 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OWF51460.1 - 2.9e-20 72.3 46.1 0.0016 18.7 1.2 15.1 14 3 1 15 15 14 5 Tetratricopeptide repeat TPR_6 PF13174.6 OWF51460.1 - 7e-18 64.0 48.8 0.56 11.0 0.0 21.2 24 1 0 24 24 22 4 Tetratricopeptide repeat TPR_11 PF13414.6 OWF51460.1 - 6.3e-15 54.6 16.1 4.9e-05 22.9 0.0 10.7 11 2 1 12 12 12 4 TPR repeat TPR_21 PF09976.9 OWF51460.1 - 9.7e-10 38.5 39.2 0.0049 16.6 4.6 8.6 5 2 3 9 9 9 4 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 OWF51460.1 - 2.7e-09 36.7 36.5 0.0051 16.1 8.0 9.1 5 2 3 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 OWF51460.1 - 6.5e-09 35.6 24.3 3.5 8.2 0.0 14.4 17 0 0 17 17 15 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF51460.1 - 2.3e-07 30.5 25.2 1.1 9.2 0.1 12.3 12 1 1 13 13 12 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF51460.1 - 9.1e-07 28.9 14.2 0.097 12.8 0.0 9.3 8 2 2 10 10 8 2 Tetratricopeptide repeat TPR_20 PF14561.6 OWF51460.1 - 1.6e-06 28.4 29.7 4.1 7.8 0.1 12.8 8 2 7 15 15 14 1 Tetratricopeptide repeat TPR_4 PF07721.14 OWF51460.1 - 1.4e-05 25.3 14.0 30 5.6 0.0 9.5 11 0 0 11 11 8 0 Tetratricopeptide repeat Sel1 PF08238.12 OWF51460.1 - 0.0021 18.7 11.1 12 6.8 0.2 6.8 6 0 0 6 6 5 0 Sel1 repeat Wzy_C_2 PF11846.8 OWF51460.1 - 0.014 15.3 2.5 14 5.5 0.0 4.5 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Vir_act_alpha_C PF10400.9 OWF51460.1 - 0.019 15.6 1.1 2 9.2 0.2 3.4 2 0 0 2 2 2 0 Virulence activator alpha C-term Fis1_TPR_C PF14853.6 OWF51460.1 - 0.036 14.1 19.2 3.5 7.8 0.1 8.9 9 0 0 9 9 9 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 OWF51460.1 - 0.23 11.1 13.3 1.8 8.2 0.1 6.4 8 0 0 8 8 6 0 Bacterial type III secretion protein (HrpB1_HrpK) ChAPs PF09295.10 OWF51460.1 - 0.29 10.1 0.0 0.29 10.1 0.0 4.9 4 2 2 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 OWF51460.1 - 1.4 9.1 23.8 0.65 10.1 0.3 8.9 9 1 1 10 10 10 0 MIT (microtubule interacting and transport) domain YfdX PF10938.8 OWF51460.1 - 3 7.7 17.4 0.25 11.3 0.1 6.0 6 2 0 6 6 4 0 YfdX protein DUF3808 PF10300.9 OWF51460.1 - 3.7 6.2 17.6 0.63 8.7 0.2 6.0 5 2 2 7 7 7 0 Protein of unknown function (DUF3808) Spore_YhaL PF14147.6 OWF51461.1 - 3.2 7.5 4.4 9.6 6.0 4.4 1.8 1 0 0 1 1 1 0 Sporulation protein YhaL EGF PF00008.27 OWF51462.1 - 1.8e-13 50.5 57.6 0.00045 20.5 8.6 4.7 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 OWF51462.1 - 4.9e-05 23.8 45.2 0.12 13.0 3.0 6.0 5 1 1 6 6 6 4 Human growth factor-like EGF DASH_Dam1 PF08653.10 OWF51462.1 - 0.057 13.2 1.1 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 EGF_3 PF12947.7 OWF51462.1 - 0.062 13.5 48.8 0.1 12.8 6.1 4.7 3 2 1 4 4 4 0 EGF domain CHASE8 PF17152.4 OWF51462.1 - 0.063 13.5 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Periplasmic sensor domain BLOC1_2 PF10046.9 OWF51462.1 - 0.29 11.5 3.7 2 8.8 4.0 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT_CC PF16559.5 OWF51462.1 - 0.33 10.9 3.2 6.2 6.8 0.5 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 OWF51462.1 - 0.84 9.9 2.8 7.3 6.9 1.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 OWF51462.1 - 0.98 9.9 4.7 6.7 7.3 0.7 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein VWA_2 PF13519.6 OWF51464.1 - 1.3e-07 32.2 0.0 1.3e-07 32.2 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 OWF51464.1 - 0.0003 21.1 0.9 0.0003 21.1 0.9 2.6 3 0 0 3 3 3 1 von Willebrand factor type A domain Ephrin_rec_like PF07699.13 OWF51465.1 - 1.1e-28 98.7 47.5 8.8e-11 41.4 12.5 5.6 3 2 2 5 5 5 3 Putative ephrin-receptor like HYR PF02494.16 OWF51465.1 - 3.7e-22 78.4 6.8 9.4e-12 45.1 0.3 3.3 3 0 0 3 3 3 2 HYR domain TSP_1 PF00090.19 OWF51465.1 - 6.1e-13 48.8 5.7 6.1e-13 48.8 5.7 4.8 4 0 0 4 4 4 1 Thrombospondin type 1 domain EGF PF00008.27 OWF51465.1 - 4.1e-06 27.0 35.3 7.3e-06 26.2 5.8 5.1 4 0 0 4 4 4 2 EGF-like domain Sushi PF00084.20 OWF51465.1 - 3.3e-05 24.4 6.0 0.0012 19.4 0.1 9.0 8 0 0 8 8 8 4 Sushi repeat (SCR repeat) hEGF PF12661.7 OWF51465.1 - 0.00014 22.4 6.3 0.00014 22.4 6.3 7.0 7 0 0 7 7 7 2 Human growth factor-like EGF DUF5011 PF16403.5 OWF51465.1 - 0.0025 17.9 0.1 0.0083 16.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5011) EphA2_TM PF14575.6 OWF51465.1 - 0.13 13.2 0.0 0.36 11.7 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FGFR3_TM PF18123.1 OWF51465.1 - 7.6 6.2 9.0 8.4 6.0 4.0 2.4 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain Sushi PF00084.20 OWF51466.1 - 1.3e-16 60.9 11.1 6.6e-11 42.6 1.2 3.3 2 1 0 2 2 2 2 Sushi repeat (SCR repeat) EGF PF00008.27 OWF51466.1 - 2.2e-08 34.3 7.2 2.2e-08 34.3 7.2 4.1 3 0 0 3 3 3 1 EGF-like domain HYR PF02494.16 OWF51466.1 - 7.4e-07 29.4 0.4 1.5e-06 28.4 0.4 1.5 1 0 0 1 1 1 1 HYR domain hEGF PF12661.7 OWF51466.1 - 0.00032 21.2 7.5 0.00032 21.2 7.5 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 OWF51466.1 - 0.0024 18.2 9.7 0.0024 18.2 9.7 4.2 4 0 0 4 4 4 1 EGF-like domain zf-B_box PF00643.24 OWF51467.1 - 3.3e-07 30.4 27.9 5.1e-05 23.3 11.5 2.6 2 0 0 2 2 2 2 B-box zinc finger FAM150 PF15129.6 OWF51467.1 - 0.0049 17.0 0.7 0.0049 17.0 0.7 1.7 2 0 0 2 2 2 1 FAM150 family HNF_C PF09354.10 OWF51467.1 - 0.022 15.8 0.1 0.043 14.9 0.1 1.5 1 0 0 1 1 1 0 HNF3 C-terminal domain DUF3795 PF12675.7 OWF51467.1 - 0.025 15.0 3.6 0.025 15.0 3.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3795) DUF4062 PF13271.6 OWF51467.1 - 0.038 14.4 0.2 0.11 12.9 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4062) zf-piccolo PF05715.13 OWF51467.1 - 1.2 9.4 16.9 3.6 7.8 8.1 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger zf-RING_UBOX PF13445.6 OWF51468.1 - 8.8e-10 38.4 2.3 8.8e-10 38.4 2.3 3.1 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF51468.1 - 9e-09 35.5 7.5 9e-09 35.5 7.5 6.4 6 1 0 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF51468.1 - 2e-08 33.9 6.7 2e-08 33.9 6.7 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF51468.1 - 2.3e-08 33.7 6.4 2.3e-08 33.7 6.4 6.0 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51468.1 - 6.2e-08 32.7 6.1 6.2e-08 32.7 6.1 5.1 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF51468.1 - 7e-08 32.2 5.1 7e-08 32.2 5.1 5.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF51468.1 - 4.3e-07 29.8 7.2 4.3e-07 29.8 7.2 5.8 6 0 0 6 6 6 1 zinc-RING finger domain zf-B_box PF00643.24 OWF51468.1 - 2.1e-06 27.8 5.3 2.1e-06 27.8 5.3 6.9 6 1 1 7 7 7 3 B-box zinc finger zf-RING_2 PF13639.6 OWF51469.1 - 7e-08 32.7 12.5 7e-08 32.7 12.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 OWF51469.1 - 1.1e-07 31.6 12.9 1.1e-07 31.6 12.9 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51469.1 - 1.8e-06 28.0 10.7 1.8e-06 28.0 10.7 3.9 4 1 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF51469.1 - 3e-06 27.0 11.2 3e-06 27.0 11.2 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF51469.1 - 6.7e-06 26.2 4.6 6.7e-06 26.2 4.6 4.3 4 2 1 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF51469.1 - 1.2e-05 25.3 6.1 1.2e-05 25.3 6.1 3.9 4 1 0 4 4 4 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF51469.1 - 0.00014 21.7 12.9 0.00014 21.7 12.9 4.1 3 3 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OWF51469.1 - 0.0008 19.2 4.9 0.0008 19.2 4.9 2.7 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OWF51469.1 - 0.0012 18.7 12.8 0.0012 18.7 12.8 3.3 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OWF51469.1 - 0.0077 16.0 4.2 0.0077 16.0 4.2 3.1 3 0 0 3 3 3 1 RING-like zinc finger Transp_Tc5_C PF04236.15 OWF51469.1 - 0.031 14.6 3.1 0.031 14.6 3.1 3.5 3 1 0 3 3 2 0 Tc5 transposase C-terminal domain DUF2715 PF10895.8 OWF51470.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) TMEM154 PF15102.6 OWF51470.1 - 1.9 8.4 6.6 0.86 9.5 0.7 2.9 1 1 1 2 2 2 0 TMEM154 protein family Ferrochelatase PF00762.19 OWF51471.1 - 7.9e-109 363.6 0.0 9.4e-109 363.3 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase zf-RING_UBOX PF13445.6 OWF51472.1 - 2e-08 34.1 1.5 2e-08 34.1 1.5 3.8 4 1 1 5 5 5 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF51472.1 - 3.2e-08 33.8 6.4 3.2e-08 33.8 6.4 3.9 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF51472.1 - 3.2e-08 33.3 7.0 3.2e-08 33.3 7.0 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF51472.1 - 4.3e-08 33.2 9.1 4.3e-08 33.2 9.1 4.0 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF51472.1 - 5.2e-08 32.6 5.4 5.2e-08 32.6 5.4 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF51472.1 - 1.8e-07 30.9 5.8 1.8e-07 30.9 5.8 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51472.1 - 5.6e-07 29.6 6.5 5.6e-07 29.6 6.5 3.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF51472.1 - 9.1e-06 25.5 7.3 9.1e-06 25.5 7.3 4.0 2 1 1 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF51472.1 - 0.00019 21.2 5.8 0.00019 21.2 5.8 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF51472.1 - 0.035 13.8 4.1 0.035 13.8 4.1 3.2 3 1 0 3 3 3 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF51473.1 - 1.9e-07 30.8 4.0 1.9e-07 30.8 4.0 4.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF51473.1 - 5.2e-07 29.4 2.6 5.2e-07 29.4 2.6 4.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF51473.1 - 2.6e-06 27.2 1.8 2.6e-06 27.2 1.8 3.6 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51473.1 - 3e-06 27.3 1.2 3e-06 27.3 1.2 4.6 4 2 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF51473.1 - 3.2e-05 24.2 2.6 3.2e-05 24.2 2.6 3.9 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF51473.1 - 0.00023 21.1 0.4 0.00023 21.1 0.4 4.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 OWF51473.1 - 0.00026 21.1 8.0 0.00026 21.1 8.0 4.6 4 2 0 4 4 4 1 B-box zinc finger Prok-RING_4 PF14447.6 OWF51473.1 - 0.027 14.3 3.0 0.027 14.3 3.0 4.7 3 3 2 5 5 5 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 OWF51473.1 - 0.083 12.7 10.0 6.1 6.8 0.1 4.1 4 0 0 4 4 4 0 Rad50 zinc hook motif SLATT_fungal PF18142.1 OWF51473.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain CBFB_NFYA PF02045.15 OWF51475.1 - 2.2e-25 89.1 4.3 3.2e-25 88.5 4.3 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Coprogen_oxidas PF01218.18 OWF51475.1 - 0.17 10.6 0.1 0.44 9.2 0.0 1.7 2 0 0 2 2 2 0 Coproporphyrinogen III oxidase NAGidase PF07555.13 OWF51476.1 - 5.2e-80 268.9 0.0 9.8e-80 268.0 0.0 1.4 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase DHHC PF01529.20 OWF51477.1 - 2.6e-26 92.3 11.1 2.6e-26 92.3 11.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase VIT PF08487.10 OWF51478.1 - 0.0023 18.1 4.4 0.44 10.8 0.8 3.0 1 1 1 2 2 2 2 Vault protein inter-alpha-trypsin domain D_CNTX PF17492.2 OWF51478.1 - 0.0034 17.5 19.5 0.4 10.9 0.8 5.5 3 1 0 4 4 4 1 Delta Ctenitoxins Methyltransf_16 PF10294.9 OWF51478.1 - 0.018 14.8 1.0 2.5 7.8 0.1 2.1 1 1 1 2 2 2 0 Lysine methyltransferase BD_b_sandwich PF18820.1 OWF51478.1 - 0.023 14.7 0.3 1.3 9.0 0.0 2.1 1 1 0 2 2 2 0 Bdellovibrio Beta-sandwich LigA PF07746.11 OWF51478.1 - 0.025 14.7 0.0 8.8 6.6 0.0 2.8 1 1 2 3 3 3 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Gal_mutarotas_3 PF18080.1 OWF51478.1 - 0.25 11.3 5.0 2.6 7.9 1.3 2.3 1 1 1 2 2 2 0 Galactose mutarotase-like fold domain NOG1 PF06858.14 OWF51478.1 - 1.1 9.1 7.6 11 5.9 0.5 3.5 2 2 2 4 4 4 0 Nucleolar GTP-binding protein 1 (NOG1) DUF5404 PF17397.2 OWF51478.1 - 1.1 9.4 7.9 2.8 8.1 3.8 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5404) A_amylase_inhib PF01356.19 OWF51478.1 - 1.7 8.7 11.3 0.86 9.7 0.3 3.1 1 1 2 3 3 3 0 Alpha amylase inhibitor HECT PF00632.25 OWF51479.1 - 3.2e-10 40.0 0.0 4.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PRAS PF15798.5 OWF51480.1 - 3.3e-27 95.6 3.2 2.4e-26 92.8 2.0 2.7 3 0 0 3 3 3 1 Proline-rich AKT1 substrate 1 BPS1 PF05633.11 OWF51480.1 - 0.015 14.4 0.3 0.029 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein BYPASS1-related Prp19 PF08606.11 OWF51480.1 - 0.086 12.8 1.4 0.16 11.9 1.4 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like DUF1057 PF06342.12 OWF51481.1 - 3.4e-06 26.3 0.0 4.2e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 OWF51481.1 - 0.0096 16.5 0.0 0.019 15.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OWF51481.1 - 0.14 12.0 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Oxysterol_BP PF01237.18 OWF51482.1 - 1.9e-78 263.9 3.8 1e-76 258.2 3.8 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 OWF51482.1 - 1.5e-12 47.9 0.6 5e-12 46.3 0.1 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 OWF51482.1 - 1.3e-08 35.0 0.1 2.7e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 OWF51482.1 - 8.4e-06 26.0 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OWF51482.1 - 0.0097 16.3 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OWF51482.1 - 0.011 16.1 0.8 0.15 12.5 0.8 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 OWF51482.1 - 0.037 13.8 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Trypan_glycop_C PF10659.9 OWF51482.1 - 0.041 14.3 0.8 0.1 12.9 0.8 1.6 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain bZIP_Maf PF03131.17 OWF51483.1 - 0.038 14.5 1.4 0.038 14.5 1.4 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor F-box-like PF12937.7 OWF51484.1 - 7.9e-15 54.5 1.4 1.7e-14 53.5 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF51484.1 - 9e-10 38.2 0.3 2.5e-09 36.8 0.3 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OWF51484.1 - 0.00053 20.3 15.5 0.051 14.0 0.1 6.1 2 1 6 8 8 8 2 Leucine Rich repeats (2 copies) PRANC PF09372.10 OWF51484.1 - 0.0057 16.9 0.0 0.022 15.1 0.0 2.0 1 0 0 1 1 1 1 PRANC domain Neur_chan_memb PF02932.16 OWF51484.1 - 0.025 14.6 0.3 0.025 14.6 0.3 4.7 4 2 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region zf-ribbon_3 PF13248.6 OWF51484.1 - 0.041 13.3 2.5 0.12 11.8 2.5 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Gp-FAR-1 PF05823.12 OWF51484.1 - 0.17 12.2 3.7 1.9 8.8 2.2 2.6 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DZR PF12773.7 OWF51484.1 - 0.21 11.6 4.2 0.1 12.6 0.7 2.3 2 0 0 2 2 2 0 Double zinc ribbon LRR_1 PF00560.33 OWF51484.1 - 5.9 7.9 19.2 37 5.4 0.1 8.6 8 1 1 9 9 9 0 Leucine Rich Repeat SF3A2 PF16835.5 OWF51485.1 - 4.8e-38 129.4 0.3 7.4e-38 128.8 0.3 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OWF51485.1 - 5.9e-07 29.7 2.0 5.9e-07 29.7 2.0 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 OWF51485.1 - 5.6e-05 23.1 0.5 8.9e-05 22.4 0.5 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 OWF51485.1 - 0.094 12.3 3.2 0.16 11.6 3.2 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like zf-C2H2_jaz PF12171.8 OWF51485.1 - 8.4 6.8 6.3 13 6.2 4.6 2.2 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ets PF00178.22 OWF51486.1 - 6.4e-32 109.9 1.9 1.1e-31 109.2 1.9 1.4 1 0 0 1 1 1 1 Ets-domain DUF4424 PF14415.6 OWF51487.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) G8 PF10162.9 OWF51488.1 - 1.3e-26 93.1 0.0 2.5e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 G8 domain TSP_1 PF00090.19 OWF51488.1 - 7.1e-05 22.9 6.5 0.00019 21.6 6.5 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain ILEI PF15711.5 OWF51488.1 - 0.022 15.2 0.2 0.078 13.5 0.0 2.0 2 0 0 2 2 2 0 Interleukin-like EMT inducer DUF5522 PF17653.1 OWF51489.1 - 4.7e-22 77.7 7.6 9.6e-22 76.7 7.6 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5522) DENN PF02141.21 OWF51490.1 - 2e-51 174.6 2.2 4.6e-51 173.4 2.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OWF51490.1 - 1.2e-12 47.6 3.0 2.8e-12 46.4 3.0 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 OWF51490.1 - 5.2e-07 30.3 1.0 1.2e-06 29.1 1.0 1.7 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 OWF51490.1 - 0.00032 20.6 0.2 0.001 19.0 0.2 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 OWF51490.1 - 0.001 17.8 1.4 0.35 9.5 0.1 2.5 1 1 1 2 2 2 2 Transport protein Avl9 Histone PF00125.24 OWF51491.1 - 1.4e-44 151.7 1.0 1.7e-44 151.4 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OWF51491.1 - 0.00014 22.2 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OWF51491.1 - 0.00097 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OWF51491.1 - 0.0092 16.3 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LSM PF01423.22 OWF51492.1 - 2.8e-17 62.1 0.1 3.4e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OWF51492.1 - 0.0033 17.5 0.1 0.0041 17.2 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Proteasome PF00227.26 OWF51493.1 - 1.7e-36 125.5 0.0 2.1e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit MBF1 PF08523.10 OWF51494.1 - 1.7e-18 66.9 5.9 1.7e-18 66.9 5.9 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OWF51494.1 - 2.6e-13 49.8 0.3 4.6e-13 49.0 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OWF51494.1 - 0.00032 21.0 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OWF51494.1 - 0.017 15.2 0.4 0.029 14.4 0.4 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Cluap1 PF10234.9 OWF51494.1 - 0.03 13.7 5.4 0.038 13.4 5.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 MqsA_antitoxin PF15731.5 OWF51494.1 - 0.083 13.0 0.5 0.21 11.7 0.3 1.7 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA CemA PF03040.14 OWF51494.1 - 1.1 9.2 4.8 1.3 8.9 4.8 1.1 1 0 0 1 1 1 0 CemA family TMPIT PF07851.13 OWF51494.1 - 1.6 7.9 7.0 1.9 7.7 7.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 OWF51494.1 - 1.9 8.5 9.8 2.2 8.3 9.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Presenilin PF01080.17 OWF51494.1 - 2.9 6.5 5.9 3.2 6.4 5.9 1.0 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 OWF51494.1 - 5.2 5.8 7.7 6.2 5.5 7.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Branch PF02485.21 OWF51495.1 - 5.3e-07 29.4 0.0 7.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 OWF51496.1 - 3.9e-38 131.4 0.0 5.9e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2809 PF10990.8 OWF51496.1 - 0.077 13.7 0.1 0.14 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) Ig_3 PF13927.6 OWF51497.1 - 6.3e-09 36.3 3.2 1.2e-05 25.8 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 OWF51497.1 - 4e-07 30.3 0.7 8.3e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 OWF51497.1 - 4.3e-06 26.8 0.1 1.4e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 OWF51497.1 - 1.6e-05 24.9 0.8 0.00039 20.4 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF51497.1 - 0.00011 22.4 0.3 0.01 16.0 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.16 OWF51497.1 - 0.00027 20.9 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain fn3 PF00041.21 OWF51497.1 - 0.0074 16.6 0.1 0.035 14.4 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain CBM_4_9 PF02018.17 OWF51497.1 - 0.022 15.0 0.1 0.073 13.3 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain Nicastrin PF05450.15 OWF51498.1 - 2.1e-58 197.6 0.3 4.1e-58 196.6 0.3 1.4 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 OWF51498.1 - 1.6e-53 181.2 0.1 1.8e-52 177.7 0.0 2.4 2 0 0 2 2 2 1 Nicastrin small lobe Peptidase_M28 PF04389.17 OWF51498.1 - 1.9e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Exosortase_EpsH PF09721.10 OWF51498.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) DUF4017 PF13209.6 OWF51498.1 - 0.15 12.0 0.2 4.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) TIR PF01582.20 OWF51499.1 - 3.8e-21 75.7 0.0 6.2e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF51499.1 - 6.3e-19 67.5 35.2 1.5e-09 37.5 10.0 5.9 4 1 1 5 5 5 5 Leucine rich repeat TIR_2 PF13676.6 OWF51499.1 - 1.9e-18 67.2 0.0 1.3e-16 61.2 0.0 2.9 3 0 0 3 3 3 1 TIR domain LRR_4 PF12799.7 OWF51499.1 - 1.2e-13 50.9 42.6 2.4e-05 24.6 2.6 7.7 6 1 1 8 8 8 6 Leucine Rich repeats (2 copies) DUF1863 PF08937.11 OWF51499.1 - 0.00097 19.5 0.1 0.0027 18.0 0.1 1.8 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_9 PF14580.6 OWF51499.1 - 0.033 13.7 11.9 1 8.9 3.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 OWF51499.1 - 6.2 7.1 36.3 0.36 11.0 0.2 8.5 9 0 0 9 9 9 0 Leucine Rich repeat Acetyltransf_18 PF18014.1 OWF51500.1 - 1.5e-20 73.3 0.0 2.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF51500.1 - 0.00044 20.5 0.0 0.74 10.1 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF51500.1 - 0.0014 18.6 0.0 0.053 13.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FAD_syn PF06574.12 OWF51500.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Galactosyl_T PF01762.21 OWF51501.1 - 3.3e-52 177.1 0.4 4.8e-52 176.6 0.4 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF51501.1 - 0.00054 19.5 0.1 0.00085 18.8 0.1 1.3 1 0 0 1 1 1 1 Fringe-like Cornifin PF02389.15 OWF51502.1 - 7.3e-13 48.9 89.6 0.11 12.7 8.4 7.1 1 1 6 7 7 7 7 Cornifin (SPRR) family Ribosomal_L12 PF00542.19 OWF51502.1 - 4.3 7.8 46.1 2e+02 2.4 0.1 16.2 2 2 16 23 23 23 0 Ribosomal protein L7/L12 C-terminal domain Galactosyl_T PF01762.21 OWF51503.1 - 2.9e-51 174.1 0.3 5.2e-51 173.2 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 OWF51503.1 - 0.0017 17.8 1.2 0.0042 16.5 1.2 1.6 1 1 0 1 1 1 1 Fringe-like UL41A PF17591.2 OWF51503.1 - 0.09 12.9 0.2 0.09 12.9 0.2 3.1 3 0 0 3 3 3 0 Herpesvirus UL41A DUF1157 PF06636.11 OWF51504.1 - 0.68 8.7 3.5 16 4.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1157) RL10P_insert PF17777.1 OWF51505.1 - 0.01 15.8 0.1 40 4.3 0.0 5.2 2 2 0 4 4 4 0 Insertion domain in 60S ribosomal protein L10P PARP PF00644.20 OWF51507.1 - 5e-25 88.2 0.4 5e-25 88.2 0.4 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 OWF51507.1 - 2.3e-11 44.1 13.2 4.4e-07 30.4 8.7 2.8 2 0 0 2 2 2 2 WWE domain zf-CCCH PF00642.24 OWF51507.1 - 0.012 15.5 21.8 0.058 13.3 6.1 3.7 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OWF51507.1 - 0.18 11.7 10.8 1.1 9.2 5.3 3.0 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OWF51507.1 - 1.5 9.0 25.5 0.37 10.9 0.2 4.6 5 0 0 5 5 5 0 Zinc finger domain DUF3024 PF11225.8 OWF51507.1 - 2.7 8.3 6.5 0.78 10.0 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) PARP PF00644.20 OWF51508.1 - 1.2e-23 83.7 1.0 1.2e-23 83.7 1.0 2.3 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.16 OWF51508.1 - 1.3e-23 84.0 0.0 4.3e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 RNA 2'-phosphotransferase, Tpt1 / KptA family WWE PF02825.20 OWF51508.1 - 3.8e-18 65.8 7.4 7.5e-13 48.9 3.6 2.7 2 0 0 2 2 2 2 WWE domain Torus PF16131.5 OWF51508.1 - 0.032 14.9 0.1 0.032 14.9 0.1 3.3 3 1 0 3 3 3 0 Torus domain Peptidase_C14 PF00656.22 OWF51510.1 - 2.5e-35 122.6 0.1 4.4e-35 121.8 0.1 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 OWF51510.1 - 1.1e-15 57.4 0.0 2.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF51510.1 - 2.9e-07 30.4 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Caspase recruitment domain GalP_UDP_transf PF01087.22 OWF51511.1 - 5.8e-06 26.9 186.9 18 5.7 2.0 25.2 1 1 22 23 23 23 15 Galactose-1-phosphate uridyl transferase, N-terminal domain 7tm_1 PF00001.21 OWF51512.1 - 5.4e-22 78.4 16.2 5.5e-18 65.2 2.3 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Synaptobrevin PF00957.21 OWF51512.1 - 4.1 7.3 6.1 3.1 7.7 0.0 3.4 2 1 1 3 3 3 0 Synaptobrevin NusG_add PF18298.1 OWF51513.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 NusG additional domain Eno-Rase_NADH_b PF12242.8 OWF51514.1 - 0.17 11.7 3.9 2.6 7.8 0.4 2.9 1 1 2 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rad21_Rec8 PF04824.16 OWF51514.1 - 0.19 11.0 0.3 78 2.7 0.0 3.3 1 1 1 3 3 3 0 Conserved region of Rad21 / Rec8 like protein RNA_lig_T4_1 PF09511.10 OWF51516.1 - 0.0015 18.4 0.5 1.2 8.9 0.2 3.2 1 1 1 2 2 2 2 RNA ligase DUF1997 PF09366.10 OWF51516.1 - 0.0031 17.7 0.9 3.6 7.7 0.1 3.7 1 1 3 4 4 4 2 Protein of unknown function (DUF1997) Rad21_Rec8 PF04824.16 OWF51516.1 - 0.071 12.4 4.8 8.8 5.7 0.1 4.8 4 2 1 5 5 5 0 Conserved region of Rad21 / Rec8 like protein XPB_DRD PF18458.1 OWF51516.1 - 0.11 12.4 8.6 85 3.1 0.2 6.8 4 2 2 6 6 6 0 Xeroderma pigmentosum group B helicase damage recognition domain PAPA-1 PF04795.12 OWF51516.1 - 1.3 9.8 3.6 37 5.2 0.1 3.4 3 1 0 3 3 3 0 PAPA-1-like conserved region Ribosomal_L30 PF00327.20 OWF51516.1 - 1.7 8.6 10.5 1.2e+02 2.7 0.0 5.9 3 1 4 7 7 7 0 Ribosomal protein L30p/L7e Pkinase_Tyr PF07714.17 OWF51517.1 - 3.2e-41 141.3 0.0 5.9e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF51517.1 - 1.1e-40 139.6 0.0 3.4e-40 138.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain COG5 PF10392.9 OWF51517.1 - 0.21 11.8 2.6 0.56 10.4 1.8 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 SSF PF00474.17 OWF51518.1 - 8.5e-26 90.7 8.8 1.4e-15 57.1 1.0 2.3 1 1 1 2 2 2 2 Sodium:solute symporter family Filamin PF00630.19 OWF51519.1 - 0.00055 20.7 0.0 0.0024 18.7 0.0 2.0 1 1 0 1 1 1 1 Filamin/ABP280 repeat Neurexophilin PF06312.12 OWF51519.1 - 0.00073 19.1 0.0 0.0029 17.1 0.0 1.9 1 1 1 2 2 2 1 Neurexophilin FemAB_like PF04339.12 OWF51519.1 - 0.18 10.9 1.8 0.28 10.2 1.8 1.2 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Neurexophilin PF06312.12 OWF51520.1 - 0.00039 19.9 0.1 0.00083 18.9 0.1 1.6 1 0 0 1 1 1 1 Neurexophilin Vma12 PF11712.8 OWF51521.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FTCD_N PF07837.12 OWF51522.1 - 1.1e-14 54.6 0.0 8.4 6.1 0.0 12.4 1 1 12 13 13 13 9 Formiminotransferase domain, N-terminal subdomain Imm17 PF15562.6 OWF51522.1 - 3.4e-12 46.0 31.1 45 4.0 0.1 17.1 1 1 22 23 23 23 12 Immunity protein 17 KIAA1430 PF13879.6 OWF51524.1 - 4.9e-26 91.5 8.3 4.9e-26 91.5 8.3 2.7 2 1 0 2 2 2 1 KIAA1430 homologue Kei1 PF08552.11 OWF51524.1 - 7 6.5 7.2 11 5.9 7.2 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 WD40 PF00400.32 OWF51525.1 - 1.7e-13 50.8 9.8 0.0039 18.0 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF51525.1 - 1.6e-09 37.9 1.3 0.019 15.3 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 OWF51525.1 - 0.017 14.7 0.3 0.16 11.5 0.0 2.4 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 OWF51525.1 - 0.018 14.4 0.9 0.04 13.3 0.9 1.5 1 0 0 1 1 1 0 WD40-like domain eIF2A PF08662.11 OWF51525.1 - 0.052 13.4 0.2 0.16 11.8 0.2 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A AMMECR1 PF01871.17 OWF51526.1 - 8.3e-41 139.4 0.0 9.8e-41 139.1 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 PARG_cat PF05028.14 OWF51527.1 - 3.3e-102 342.2 0.0 1.7e-82 277.5 0.0 2.3 2 0 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) RNA_pol_Rpb1_1 PF04997.12 OWF51528.1 - 2.1e-108 362.3 2.0 2.5e-108 362.1 0.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OWF51528.1 - 6.2e-101 337.3 0.1 9.5e-101 336.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OWF51528.1 - 3.2e-74 248.7 0.1 5.9e-74 247.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OWF51528.1 - 9.6e-65 218.0 0.0 2.5e-64 216.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 OWF51528.1 - 1.7e-55 186.7 5.0 4.3e-55 185.4 5.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 OWF51528.1 - 3.9e-48 163.3 0.0 1e-47 162.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OWF51528.1 - 1.7e-38 130.9 0.4 2.3e-37 127.2 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OWF51528.1 - 1.5e-16 59.7 586.0 0.0087 16.4 11.9 28.8 6 2 42 48 48 48 40 RNA polymerase Rpb1 C-terminal repeat Glyco_transf_10 PF00852.19 OWF51529.1 - 1.5e-48 164.9 5.1 1.5e-48 164.9 5.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF51529.1 - 8.2e-20 71.3 4.6 1e-19 71.0 2.6 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Mab-21 PF03281.14 OWF51530.1 - 4.5e-18 65.6 0.0 1.8e-17 63.6 0.0 1.9 1 1 0 1 1 1 1 Mab-21 protein FXa_inhibition PF14670.6 OWF51531.1 - 7.2 7.0 15.1 1.8 8.9 4.5 3.9 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site NapE PF06796.11 OWF51535.1 - 1.7 8.2 4.3 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE KRTAP PF11759.8 OWF51535.1 - 7.8 7.1 32.0 6.7 7.3 30.6 1.6 1 1 0 1 1 1 0 Keratin-associated matrix Peptidase_S64 PF08192.11 OWF51536.1 - 0.01 14.4 0.1 0.025 13.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase family S64 KaiB PF07689.12 OWF51536.1 - 0.064 13.0 0.1 0.27 11.0 0.1 2.0 1 0 0 1 1 1 0 KaiB domain Cu-binding_MopE PF11617.8 OWF51536.1 - 0.78 10.0 0.0 0.78 10.0 0.0 3.8 5 0 0 5 5 5 0 Putative metal-binding motif Synaptobrevin PF00957.21 OWF51537.1 - 3.9e-33 113.1 0.6 4.8e-33 112.8 0.6 1.1 1 0 0 1 1 1 1 Synaptobrevin Ferlin_C PF16165.5 OWF51537.1 - 0.0067 16.4 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 Ferlin C-terminus ODV-E18 PF10717.9 OWF51537.1 - 0.013 15.4 0.6 0.023 14.5 0.6 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2275 PF10039.9 OWF51537.1 - 0.023 14.8 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) LRRC37AB_C PF14914.6 OWF51537.1 - 0.053 13.4 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain SNARE PF05739.19 OWF51537.1 - 0.068 13.2 5.4 0.14 12.2 5.4 1.6 1 0 0 1 1 1 0 SNARE domain UPF0258 PF06789.12 OWF51537.1 - 0.07 13.3 0.1 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) TMC PF07810.13 OWF51539.1 - 1.4e-33 115.7 2.3 1.4e-33 115.7 2.3 3.5 5 1 1 6 6 6 1 TMC domain EVE PF01878.18 OWF51540.1 - 0.0059 16.6 8.4 1.5 8.8 0.2 3.2 1 1 1 3 3 3 3 EVE domain OapA PF04225.12 OWF51540.1 - 1.3 9.1 7.8 17 5.6 0.7 3.3 1 1 3 4 4 4 0 Opacity-associated protein A LysM-like domain CMD PF02627.20 OWF51541.1 - 5e-09 36.1 0.3 2.4e-08 33.9 0.1 2.0 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 OWF51541.1 - 0.002 17.1 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) V-set PF07686.17 OWF51542.1 - 1.2e-10 41.5 0.8 2.4e-07 30.9 0.3 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF51542.1 - 5.2e-08 33.1 1.7 2.6e-05 24.5 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 OWF51542.1 - 3.5e-07 30.7 4.5 0.00069 20.2 0.2 3.6 2 2 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 OWF51542.1 - 4.9e-06 26.6 1.9 0.088 13.0 0.0 3.5 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF51542.1 - 5.4e-05 23.2 0.9 0.87 9.7 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin I-set domain C2-set_2 PF08205.12 OWF51542.1 - 7.5e-05 22.7 0.1 0.0002 21.4 0.1 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain CfAFP PF05264.11 OWF51543.1 - 1.3e-09 38.2 431.3 1.8e+04 -11.5 21.7 58.1 1 1 3 4 4 4 0 Choristoneura fumiferana antifreeze protein (CfAFP) CDC45 PF02724.14 OWF51544.1 - 8.9 4.5 14.7 9.3 4.4 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein 7tm_1 PF00001.21 OWF51545.1 - 2.1e-40 138.7 14.5 3.3e-40 138.1 14.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2807 PF10988.8 OWF51546.1 - 0.072 12.9 1.8 1.4 8.7 2.3 2.0 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain zf-CCHH PF10283.9 OWF51546.1 - 4.6 7.3 17.8 54 3.9 0.1 7.4 9 0 0 9 9 9 0 PBZ domain BIR PF00653.21 OWF51547.1 - 8.3e-19 68.0 1.2 8.3e-19 68.0 1.2 2.7 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF51547.1 - 6.2e-14 51.6 7.7 6.2e-14 51.6 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF51547.1 - 3e-06 27.0 6.9 7.3e-06 25.7 6.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF51547.1 - 0.01 16.1 9.3 0.01 16.1 9.3 2.1 2 0 0 2 2 2 0 Ring finger domain Stevor PF17410.2 OWF51547.1 - 0.031 13.8 1.0 0.051 13.1 1.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame zf-RING_5 PF14634.6 OWF51547.1 - 0.18 11.8 11.9 0.036 14.0 7.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF51548.1 - 8.1e-15 54.4 7.7 1.8e-14 53.3 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF51548.1 - 1.1e-06 28.4 6.9 2.2e-06 27.4 6.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF51548.1 - 0.0012 19.1 9.3 0.0033 17.7 9.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF51548.1 - 0.0052 16.7 6.7 0.0052 16.7 6.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Stevor PF17410.2 OWF51548.1 - 0.0082 15.7 1.2 0.0093 15.5 1.2 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame zf-C3HC4_2 PF13923.6 OWF51548.1 - 0.04 13.8 9.8 0.04 13.8 9.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tim54 PF11711.8 OWF51548.1 - 0.059 12.2 0.5 0.066 12.0 0.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 zf-RING_UBOX PF13445.6 OWF51548.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-FPG_IleRS PF06827.14 OWF51548.1 - 0.16 11.9 0.8 0.16 11.9 0.8 3.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Zn-C2H2_12 PF18112.1 OWF51548.1 - 1.4 9.4 6.4 13 6.3 0.9 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 OWF51548.1 - 8.5 6.8 12.3 14 6.1 0.6 3.9 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding MFS_1 PF07690.16 OWF51550.1 - 4.6e-21 75.1 11.8 4.6e-21 75.1 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OWF51550.1 - 3.3e-09 35.6 4.1 0.00054 18.4 0.1 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF51551.1 - 1.5e-25 89.9 33.3 9.6e-21 74.1 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OWF51551.1 - 0.00032 19.2 14.0 0.0051 15.2 4.3 2.8 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Nodulin-like PF06813.13 OWF51551.1 - 0.0015 18.1 7.5 0.0021 17.6 7.5 1.3 1 0 0 1 1 1 1 Nodulin-like CPBP PF02517.16 OWF51551.1 - 0.073 13.5 2.8 0.33 11.3 2.8 2.2 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease Sugar_tr PF00083.24 OWF51551.1 - 0.079 11.8 23.1 0.18 10.6 11.3 2.6 1 1 2 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 OWF51552.1 - 2.1e-22 79.5 29.0 2.2e-20 72.9 13.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OWF51552.1 - 0.00036 19.0 15.3 0.0057 15.0 4.1 2.6 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF639 PF04842.12 OWF51552.1 - 0.03 13.7 0.5 5.9 6.2 0.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF639) Sugar_tr PF00083.24 OWF51552.1 - 0.048 12.5 20.8 0.052 12.4 10.7 2.3 1 1 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 OWF51553.1 - 1.8e-31 109.3 49.5 8.9e-28 97.2 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OWF51553.1 - 0.00031 19.2 1.9 0.00031 19.2 1.9 3.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OWF51553.1 - 0.11 11.3 33.8 0.61 8.9 12.0 3.0 1 1 1 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 OWF51554.1 - 4.2e-25 88.4 28.0 6e-19 68.2 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OWF51554.1 - 5.9e-05 21.6 15.8 0.00022 19.7 1.2 2.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OWF51554.1 - 0.013 14.4 22.0 0.26 10.1 2.7 2.3 1 1 1 2 2 2 0 Sugar (and other) transporter NDUF_B12 PF08122.12 OWF51554.1 - 0.15 12.1 0.5 31 4.7 0.0 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family CPBP PF02517.16 OWF51554.1 - 0.96 9.9 5.6 1.2 9.5 3.8 2.2 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease Thioredoxin_6 PF13848.6 OWF51555.1 - 4.4e-43 147.3 0.1 8.4e-41 139.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 OWF51555.1 - 9.9e-21 73.7 0.0 2.3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.17 OWF51555.1 - 2.8e-11 43.1 0.0 3.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 OWF51555.1 - 0.0013 19.0 0.1 0.0065 16.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 OWF51555.1 - 0.0083 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family PHTB1_N PF14727.6 OWF51556.1 - 1.6e-156 521.8 0.0 2e-156 521.5 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 OWF51556.1 - 7.4e-142 472.9 0.0 1e-141 472.5 0.0 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus VWD PF00094.25 OWF51557.1 - 6.5e-36 124.0 0.1 1.2e-35 123.2 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.18 OWF51557.1 - 8e-28 96.5 150.8 1.2e-10 41.5 12.8 8.0 6 1 2 8 8 8 5 von Willebrand factor type C domain C8 PF08742.11 OWF51557.1 - 6e-15 55.4 12.6 6e-15 55.4 12.6 4.7 5 2 0 5 5 5 1 C8 domain TIL PF01826.17 OWF51557.1 - 9.4e-09 35.4 19.1 9.4e-09 35.4 19.1 9.8 4 2 2 6 6 6 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 OWF51557.1 - 0.018 15.0 7.0 0.018 15.0 7.0 9.7 6 3 3 10 10 10 0 TILa domain ISG65-75 PF11727.8 OWF51559.1 - 0.18 11.0 5.6 0.23 10.7 5.6 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein M16C_assoc PF08367.11 OWF51559.1 - 0.27 10.3 4.4 0.35 9.9 4.4 1.2 1 0 0 1 1 1 0 Peptidase M16C associated DUF4407 PF14362.6 OWF51559.1 - 0.44 9.8 2.8 0.63 9.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ly49 PF08391.10 OWF51559.1 - 0.67 10.3 3.5 1 9.7 3.5 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4200 PF13863.6 OWF51559.1 - 0.67 10.4 10.1 0.91 9.9 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FliJ PF02050.16 OWF51559.1 - 0.89 9.8 13.3 1.2 9.3 13.3 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein V_ATPase_I PF01496.19 OWF51559.1 - 1.6 6.5 3.9 2 6.2 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 OWF51559.1 - 2.2 9.0 13.7 0.13 12.9 1.8 2.3 2 0 0 2 2 2 0 SlyX CENP-K PF11802.8 OWF51559.1 - 2.7 7.5 10.4 4.9 6.6 10.4 1.4 1 1 0 1 1 1 0 Centromere-associated protein K AMP-binding PF00501.28 OWF51560.1 - 1.9e-64 217.9 0.0 2.2e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51560.1 - 3.4e-07 31.2 0.0 6.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF51561.1 - 6.7e-63 212.7 0.0 8e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51561.1 - 2.6e-08 34.7 0.0 5.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF51562.1 - 9.3e-61 205.7 0.0 1.1e-60 205.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51562.1 - 7.3e-08 33.3 0.1 1.6e-07 32.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TIR_2 PF13676.6 OWF51563.1 - 6.7e-21 75.1 0.1 1.4e-20 74.1 0.1 1.5 1 0 0 1 1 1 1 TIR domain I-set PF07679.16 OWF51563.1 - 1.4e-19 70.0 0.5 1e-09 38.3 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF51563.1 - 2.3e-18 66.6 0.4 8.3e-09 35.9 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain TIR PF01582.20 OWF51563.1 - 3.5e-18 66.0 0.0 3.5e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 TIR domain ig PF00047.25 OWF51563.1 - 6.2e-14 51.9 4.2 5.6e-08 32.8 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF51563.1 - 4e-12 46.3 1.2 4e-07 30.3 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain DUF1863 PF08937.11 OWF51563.1 - 0.00013 22.3 0.6 0.00013 22.3 0.6 2.4 2 1 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) Ig_C17orf99 PF17736.1 OWF51563.1 - 0.00033 20.6 0.0 0.0018 18.3 0.0 2.3 2 1 0 2 2 2 1 C17orf99 Ig domain V-set PF07686.17 OWF51563.1 - 0.0034 17.5 9.3 0.066 13.4 0.6 4.1 2 2 1 3 3 3 1 Immunoglobulin V-set domain TIR_3 PF18567.1 OWF51563.1 - 0.06 13.3 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain C1-set PF07654.15 OWF51563.1 - 0.062 13.7 0.7 0.62 10.5 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Sirohm_synth_C PF14823.6 OWF51563.1 - 0.58 9.8 4.6 1.3 8.7 3.0 2.2 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal UQ_con PF00179.26 OWF51564.1 - 4.1e-46 156.1 0.0 5e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF51564.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 OWF51564.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 UEV domain DNA_primase_lrg PF04104.14 OWF51565.1 - 4e-39 134.6 0.5 7.6e-39 133.7 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit NAD_binding_8 PF13450.6 OWF51566.1 - 4.3e-11 42.9 0.0 8.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OWF51566.1 - 1.2e-10 41.4 0.0 2.8e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OWF51566.1 - 8.1e-06 25.3 0.0 0.00035 19.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF51566.1 - 0.00014 22.3 0.0 0.015 15.9 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF51566.1 - 0.00031 20.5 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OWF51566.1 - 0.00063 18.5 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OWF51566.1 - 0.0039 16.4 0.0 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF51566.1 - 0.0058 15.9 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OWF51566.1 - 0.0079 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OWF51566.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain SRI PF08236.11 OWF51568.1 - 2.6e-24 85.2 7.2 2.6e-24 85.2 7.2 2.8 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 OWF51568.1 - 1.2e-14 55.0 0.0 1.2e-14 55.0 0.0 7.0 5 1 0 5 5 5 1 SET domain AWS PF17907.1 OWF51568.1 - 6.6e-11 42.1 7.7 1.5e-10 41.0 7.7 1.6 1 0 0 1 1 1 1 AWS domain WW PF00397.26 OWF51568.1 - 9e-10 38.5 3.4 2.5e-09 37.1 3.4 1.9 1 0 0 1 1 1 1 WW domain DUF587 PF04532.12 OWF51568.1 - 0.59 9.4 2.1 1.1 8.5 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF587) Pre-SET PF05033.16 OWF51568.1 - 4.4 8.0 12.0 2.8 8.6 7.3 3.2 3 0 0 3 3 3 0 Pre-SET motif Apolipoprotein PF01442.18 OWF51569.1 - 1.3e-06 28.4 5.3 0.011 15.6 0.5 2.4 1 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain TPR_7 PF13176.6 OWF51569.1 - 0.00015 21.5 0.3 16 5.8 0.0 6.4 3 3 3 6 6 6 2 Tetratricopeptide repeat PIN_8 PF18476.1 OWF51569.1 - 0.17 11.7 18.4 2.5 7.9 3.9 3.1 1 1 2 3 3 3 0 PIN like domain Nepo_coat_C PF03688.14 OWF51569.1 - 2.5 7.9 11.3 8.7 6.2 1.3 2.9 1 1 3 4 4 4 0 Nepovirus coat protein, C-terminal domain NPR1_interact PF15699.5 OWF51569.1 - 6.6 7.4 11.2 59 4.4 0.3 3.7 1 1 1 2 2 2 0 NPR1 interacting SUI1 PF01253.22 OWF51570.1 - 5.6e-27 94.1 0.1 8.6e-27 93.5 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 OWF51570.1 - 0.082 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) La PF05383.17 OWF51571.1 - 4.1e-14 52.4 0.2 7.5e-14 51.5 0.2 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OWF51571.1 - 0.17 11.7 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vac7 PF12751.7 OWF51572.1 - 0.0079 15.7 0.1 0.0099 15.4 0.1 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 ETRAMP PF09716.10 OWF51572.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) VSP PF03302.13 OWF51572.1 - 0.02 13.8 0.1 0.023 13.6 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SNARE PF05739.19 OWF51572.1 - 0.048 13.7 7.5 0.069 13.2 6.7 1.7 1 1 1 2 2 2 0 SNARE domain DotU PF09850.9 OWF51572.1 - 0.061 13.0 0.2 0.075 12.7 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF2207 PF09972.9 OWF51572.1 - 0.071 11.9 0.1 0.075 11.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 OWF51572.1 - 0.072 12.9 0.8 0.082 12.7 0.8 1.1 1 0 0 1 1 1 0 Fatty acid desaturase EOS1 PF12326.8 OWF51572.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 N-glycosylation protein DUF515 PF04415.12 OWF51572.1 - 0.25 9.7 0.9 0.3 9.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FeoB_associated PF12669.7 OWF51572.1 - 0.36 11.3 3.6 0.84 10.1 3.6 1.7 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Herpes_US9 PF06072.11 OWF51572.1 - 7.1 6.6 8.6 22 5.0 8.6 1.8 1 1 0 1 1 1 0 Alphaherpesvirus tegument protein US9 TT_ORF1 PF02956.14 OWF51572.1 - 8.6 4.9 12.7 9.8 4.7 12.7 1.0 1 0 0 1 1 1 0 TT viral orf 1 PLAC8 PF04749.17 OWF51573.1 - 1.1e-21 77.6 1.7 1.3e-21 77.4 1.7 1.0 1 0 0 1 1 1 1 PLAC8 family Spaetzle PF16077.5 OWF51574.1 - 5.6e-06 26.8 7.5 5.6e-06 26.8 7.5 1.8 2 0 0 2 2 2 1 Spaetzle ADAM_CR_2 PF17771.1 OWF51575.1 - 2.6e-05 24.7 0.8 9.4e-05 22.8 0.8 2.0 1 0 0 1 1 1 1 ADAM cysteine-rich domain GREB1 PF15782.5 OWF51575.1 - 0.8 6.7 7.2 0.98 6.4 7.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GON PF08685.11 OWF51576.1 - 1.2e-28 100.3 2.8 2.3e-27 96.2 2.8 2.2 1 1 0 1 1 1 1 GON domain Mod_r PF07200.13 OWF51576.1 - 0.001 19.2 2.8 0.0018 18.4 2.8 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 OWF51576.1 - 0.012 14.2 0.4 0.019 13.6 0.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4404 PF14357.6 OWF51576.1 - 0.014 16.1 1.3 0.029 15.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) COLFI PF01410.18 OWF51576.1 - 0.027 13.8 0.0 0.061 12.6 0.0 1.6 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Snapin_Pallidin PF14712.6 OWF51576.1 - 0.029 14.8 2.5 3.4 8.2 1.8 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DUF812 PF05667.11 OWF51576.1 - 0.033 13.1 3.0 0.043 12.7 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EzrA PF06160.12 OWF51576.1 - 0.038 12.2 2.2 0.061 11.5 2.2 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF948 PF06103.11 OWF51576.1 - 0.062 13.6 1.4 0.32 11.3 1.4 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OWF51576.1 - 0.076 13.1 4.0 0.9 9.6 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3847 PF12958.7 OWF51576.1 - 0.083 13.0 0.6 0.14 12.3 0.2 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3847) Prominin PF05478.11 OWF51576.1 - 0.091 10.7 2.0 0.12 10.3 2.0 1.1 1 0 0 1 1 1 0 Prominin KxDL PF10241.9 OWF51576.1 - 0.097 13.0 3.9 1.1 9.6 1.8 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.12 OWF51576.1 - 0.1 12.6 3.2 1 9.4 3.4 2.1 1 1 1 2 2 2 0 Laminin Domain II Adaptin_binding PF10199.9 OWF51576.1 - 0.13 12.9 2.0 0.22 12.1 2.0 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Exonuc_VII_L PF02601.15 OWF51576.1 - 0.14 11.7 4.4 0.15 11.6 3.0 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 OWF51576.1 - 0.21 11.9 3.1 1.2 9.5 1.6 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_UL6 PF01763.16 OWF51576.1 - 0.24 9.9 2.5 0.34 9.4 2.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Phasin PF05597.11 OWF51576.1 - 0.28 11.2 2.6 0.37 10.8 1.2 1.8 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.10 OWF51576.1 - 0.32 11.2 7.5 0.1 12.8 3.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family C4bp_oligo PF18453.1 OWF51577.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha Pkinase PF00069.25 OWF51578.1 - 1.7e-50 171.9 0.0 3.9e-50 170.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51578.1 - 9.4e-48 162.7 0.0 1.3e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF51578.1 - 4.7e-06 26.1 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OWF51578.1 - 0.0032 16.3 0.1 0.0079 15.0 0.1 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF51578.1 - 0.0061 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OWF51579.1 - 7.4e-42 143.5 0.0 8.7e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51579.1 - 1.2e-37 129.7 0.0 1.4e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF51579.1 - 0.0029 17.0 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF51579.1 - 0.063 12.6 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF51579.1 - 0.09 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OWF51581.1 - 3.3e-49 167.6 0.0 3.9e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51581.1 - 4.8e-47 160.4 0.0 5.7e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF51581.1 - 3.1e-08 33.3 0.0 4.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF51581.1 - 0.00041 19.8 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OWF51581.1 - 0.001 18.0 0.1 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase AMP-binding PF00501.28 OWF51582.1 - 9.4e-20 70.6 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51582.1 - 0.008 17.1 0.0 0.018 16.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF51583.1 - 2.5e-66 224.0 0.0 3.1e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51583.1 - 0.00037 21.4 0.0 0.00098 20.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1508 PF07411.12 OWF51584.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) DUF3128 PF11326.8 OWF51585.1 - 0.0011 19.3 3.5 5.8 7.4 0.1 4.6 4 1 0 4 4 4 2 Protein of unknown function (DUF3128) Crystall_2 PF09076.10 OWF51585.1 - 0.67 9.9 3.9 46 4.0 0.0 3.8 4 0 0 4 4 4 0 Beta/Gamma crystallin Keratin_B2_2 PF13885.6 OWF51585.1 - 3.3 7.7 59.7 7.4 6.6 9.2 5.8 1 1 5 6 6 6 0 Keratin, high sulfur B2 protein EamA PF00892.20 OWF51586.1 - 3.3e-14 53.2 27.1 2.2e-10 40.8 10.8 3.1 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 OWF51586.1 - 0.00011 21.6 9.7 0.0004 19.7 9.7 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 OWF51586.1 - 0.023 14.2 14.3 0.044 13.3 5.2 3.1 2 1 1 3 3 3 0 Solute carrier family 35 EGF PF00008.27 OWF51588.1 - 1.6e-156 507.8 599.4 2.4e-07 30.9 7.8 40.5 39 1 0 39 39 39 38 EGF-like domain hEGF PF12661.7 OWF51588.1 - 8.6e-89 289.5 520.1 4.2e-06 27.2 6.2 43.1 41 2 0 41 41 41 32 Human growth factor-like EGF Laminin_G_2 PF02210.24 OWF51588.1 - 1.3e-35 122.8 9.8 1.3e-12 48.4 0.0 4.4 4 0 0 4 4 4 4 Laminin G domain EGF_CA PF07645.15 OWF51588.1 - 1.6e-35 121.0 633.3 2.4e-07 30.8 13.5 40.7 27 10 13 40 40 40 19 Calcium-binding EGF domain Laminin_G_1 PF00054.23 OWF51588.1 - 2e-31 108.9 4.0 1.7e-15 57.4 0.0 4.8 4 1 0 4 4 4 4 Laminin G domain Insulin_TMD PF17870.1 OWF51588.1 - 0.00071 19.6 0.3 0.0014 18.6 0.3 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment EGF_2 PF07974.13 OWF51588.1 - 0.0043 17.4 0.4 0.0043 17.4 0.4 39.2 36 3 2 38 38 38 14 EGF-like domain EGF_3 PF12947.7 OWF51588.1 - 0.0049 17.0 11.4 0.0049 17.0 11.4 40.1 34 4 5 39 39 39 18 EGF domain EF-hand_6 PF13405.6 OWF51589.1 - 1.4e-09 37.1 14.5 0.00029 20.5 0.2 3.9 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OWF51589.1 - 7e-09 36.0 6.2 0.0099 16.3 0.1 3.3 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF51589.1 - 1.3e-07 30.6 14.3 0.0025 17.2 0.1 3.6 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF51589.1 - 3.7e-06 26.7 8.2 0.091 12.6 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF51589.1 - 1.9e-05 23.9 8.1 0.022 14.3 0.4 3.4 3 0 0 3 3 3 2 EF hand Caleosin PF05042.13 OWF51589.1 - 0.022 14.7 1.4 0.065 13.2 0.5 2.0 1 1 0 1 1 1 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 OWF51589.1 - 0.11 12.8 2.9 2.7 8.3 2.0 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UBA PF00627.31 OWF51590.1 - 5.6e-12 45.3 0.0 2e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 OWF51590.1 - 0.0032 17.2 0.1 0.025 14.3 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 OWF51590.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 OWF51590.1 - 0.13 12.3 0.1 0.76 9.8 0.1 2.4 2 0 0 2 2 2 0 STI1 domain DUF3173 PF11372.8 OWF51590.1 - 0.14 12.0 0.0 13 5.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3173) SHIPPO-rpt PF07004.12 OWF51591.1 - 0.012 16.4 14.9 0.048 14.6 0.2 5.1 5 1 0 5 5 5 0 Sperm-tail PG-rich repeat PhyH PF05721.13 OWF51592.1 - 4.5e-21 76.1 0.2 7.2e-21 75.4 0.0 1.5 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 OWF51593.1 - 5.7e-07 30.0 0.0 5.8e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRAT PF04970.13 OWF51594.1 - 1.1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF51594.1 - 0.0011 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Calici_PP_N PF08405.11 OWF51594.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral polyprotein N-terminal LRR_8 PF13855.6 OWF51595.1 - 6.4e-16 57.9 11.9 2.7e-09 36.7 1.3 3.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF51595.1 - 2.6e-12 46.8 14.2 0.00074 19.9 0.7 4.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF51595.1 - 1.9e-11 43.8 9.0 1.9e-06 27.5 2.3 2.5 2 0 0 2 2 2 2 Leucine-rich repeat TIR PF01582.20 OWF51595.1 - 1.7e-10 41.0 0.2 2.7e-10 40.4 0.2 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF51595.1 - 1.8e-09 38.2 0.1 4.5e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF51595.1 - 0.49 11.1 7.9 4.4 8.2 0.1 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat DUF1863 PF08937.11 OWF51595.1 - 0.57 10.5 2.4 1.4 9.2 1.4 2.2 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) LRR_6 PF13516.6 OWF51595.1 - 9.1 6.6 10.3 7.9 6.8 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat N-glycanase_C PF09113.10 OWF51596.1 - 5.9e-39 133.0 0.2 1.2e-38 132.0 0.2 1.5 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal N-glycanase_N PF09112.10 OWF51596.1 - 1.5e-21 77.0 0.0 5.6e-20 71.8 0.0 2.4 1 1 0 1 1 1 1 Peptide-N-glycosidase F, N terminal PA PF02225.22 OWF51596.1 - 7.7e-08 32.3 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PA domain HEPN_DZIP3 PF18738.1 OWF51597.1 - 3.9e-06 26.7 2.5 4.3e-05 23.3 2.5 2.2 1 1 0 1 1 1 1 DZIP3/ hRUL138-like HEPN DUF1351 PF07083.11 OWF51597.1 - 0.0037 17.1 1.8 0.054 13.3 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1351) Methyltransf_21 PF05050.12 OWF51598.1 - 2.5e-11 43.9 0.2 6.7e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 OWF51598.1 - 0.018 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain V_cholerae_RfbT PF05575.11 OWF51598.1 - 0.022 14.1 0.2 0.065 12.5 0.2 1.7 1 1 0 1 1 1 0 Vibrio cholerae RfbT protein 7tm_1 PF00001.21 OWF51601.1 - 2.5e-59 200.8 19.7 3.3e-59 200.4 19.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF51601.1 - 2.1e-17 63.3 19.3 2.7e-17 63.0 19.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF51601.1 - 6.6e-07 29.2 23.1 1.9e-06 27.7 23.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF51601.1 - 0.00014 21.3 17.3 0.0038 16.6 17.3 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 OWF51601.1 - 0.00074 19.3 16.6 0.0041 16.9 16.6 2.0 1 1 0 1 1 1 1 Olfactory receptor FA_desaturase PF00487.24 OWF51602.1 - 3.2e-13 50.1 12.6 3.2e-13 50.1 12.6 1.5 1 1 1 2 2 2 2 Fatty acid desaturase CUB PF00431.20 OWF51603.1 - 5.4e-108 355.0 5.0 1.9e-28 99.0 0.0 4.4 4 0 0 4 4 4 4 CUB domain Trypsin PF00089.26 OWF51603.1 - 7.9e-70 235.1 2.7 2.4e-69 233.5 2.7 1.9 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 OWF51603.1 - 9.1e-32 109.0 53.2 3.4e-11 43.1 17.2 4.0 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A CUB_2 PF02408.20 OWF51603.1 - 2.2e-14 53.2 4.0 5.2e-05 23.0 0.3 5.0 4 2 0 4 4 4 3 CUB-like domain Trypsin_2 PF13365.6 OWF51603.1 - 0.00011 23.2 0.1 0.00038 21.4 0.1 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain MOZ_SAS PF01853.18 OWF51604.1 - 7.7e-81 270.0 0.5 1.3e-80 269.3 0.5 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OWF51604.1 - 1.7e-22 78.8 5.3 6.8e-22 76.8 5.3 2.1 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 OWF51604.1 - 3.3e-16 58.9 32.4 1.4e-09 37.7 11.6 3.0 2 1 1 3 3 3 2 PHD-finger Linker_histone PF00538.19 OWF51604.1 - 1.8e-11 44.3 0.5 4.7e-06 26.9 0.1 2.8 2 0 0 2 2 2 2 linker histone H1 and H5 family zf-C2HC PF01530.18 OWF51604.1 - 1.7e-08 34.5 0.5 4.7e-08 33.1 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2HC type TnsD PF15978.5 OWF51604.1 - 0.0024 17.0 1.8 0.0046 16.0 1.8 1.3 1 0 0 1 1 1 1 Tn7-like transposition protein D Acetyltransf_7 PF13508.7 OWF51604.1 - 0.012 16.1 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_2 PF13831.6 OWF51604.1 - 2.1 8.0 13.5 3 7.5 1.5 2.7 2 0 0 2 2 2 0 PHD-finger PD40 PF07676.12 OWF51605.1 - 0.001 18.9 0.1 0.095 12.7 0.1 2.5 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 OWF51605.1 - 0.0013 19.5 0.1 0.12 13.3 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF51605.1 - 0.0015 18.8 0.0 0.0082 16.4 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 OWF51605.1 - 0.042 13.6 0.1 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.14 OWF51605.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region TMEM237 PF15383.6 OWF51606.1 - 5.3e-53 179.7 0.1 8e-53 179.1 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 237 DUF1772 PF08592.11 OWF51606.1 - 0.26 11.6 1.6 0.42 10.9 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Peptidase_S64 PF08192.11 OWF51606.1 - 5.9 5.2 9.1 7.7 4.9 9.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 TPP_enzyme_C PF02775.21 OWF51607.1 - 7.5e-20 71.3 0.2 2.2e-19 69.8 0.2 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 OWF51607.1 - 1.1e-18 67.5 0.6 5.4e-17 61.9 0.0 2.4 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PALP PF00291.25 OWF51607.1 - 0.001 18.5 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4573 PF15140.6 OWF51608.1 - 1e-11 45.0 0.0 1.1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Plasmodium_HRP PF05403.11 OWF51608.1 - 0.0035 17.2 10.1 0.0036 17.1 10.1 1.0 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) RsbRD_N PF14361.6 OWF51608.1 - 0.005 17.5 0.8 5.5 7.7 0.2 2.9 1 1 1 2 2 2 2 RsbT co-antagonist protein rsbRD N-terminal domain Pan3_PK PF18101.1 OWF51608.1 - 0.031 14.3 0.2 7.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Pan3 Pseudokinase domain TMEM125 PF15109.6 OWF51608.1 - 0.2 12.0 3.8 5.7 7.3 0.1 3.4 1 1 3 4 4 4 0 TMEM125 protein family MIF4G PF02854.19 OWF51609.1 - 1.4e-56 191.5 3.3 1.4e-56 191.5 3.3 2.3 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.18 OWF51609.1 - 5.4e-21 74.5 2.6 2e-20 72.7 2.6 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.17 OWF51609.1 - 1.7e-14 53.8 1.7 2.3e-12 46.9 0.6 2.9 2 0 0 2 2 2 2 MA3 domain SNF PF00209.18 OWF51610.1 - 4.9e-198 659.0 35.9 7.6e-198 658.4 35.9 1.3 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DHHC PF01529.20 OWF51611.1 - 3.2e-23 82.3 16.4 3.2e-23 82.3 16.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 OWF51612.1 - 2.7e-25 89.0 9.3 2.7e-25 89.0 9.3 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2244 PF10003.9 OWF51612.1 - 2.4 7.8 7.3 3 7.5 0.5 2.9 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) RUN PF02759.19 OWF51613.1 - 1.4e-31 109.3 0.2 3.3e-31 108.0 0.0 1.8 2 0 0 2 2 2 1 RUN domain DUF4004 PF13171.6 OWF51613.1 - 0.042 14.1 3.4 0.085 13.1 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) DUF3964 PF13107.6 OWF51613.1 - 0.043 14.2 0.8 0.14 12.5 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3964) Ldl_recept_a PF00057.18 OWF51614.1 - 9.1e-28 96.2 58.7 1.4e-07 31.6 10.3 6.3 7 0 0 7 7 7 5 Low-density lipoprotein receptor domain class A 7tm_1 PF00001.21 OWF51614.1 - 3.9e-07 29.7 0.2 8.6e-07 28.5 0.2 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase_Tyr PF07714.17 OWF51614.1 - 0.0008 18.8 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF51614.1 - 0.07 12.5 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein kinase domain FA_desaturase PF00487.24 OWF51614.1 - 0.14 12.0 0.2 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 Fatty acid desaturase Ig_3 PF13927.6 OWF51615.1 - 1.7e-09 38.2 3.4 0.00018 22.0 0.3 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF51615.1 - 3.1e-06 27.2 0.4 0.015 15.3 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 OWF51615.1 - 8.7e-06 25.9 4.7 0.002 18.3 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 OWF51615.1 - 0.0003 20.9 6.2 0.1 12.8 0.7 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Caenor_Her-1 PF09232.10 OWF51615.1 - 0.0027 17.8 0.5 0.28 11.3 0.0 2.2 2 0 0 2 2 2 2 Caenorhabditis elegans Her-1 Flexi_CP PF00286.20 OWF51616.1 - 0.024 14.6 16.4 0.19 11.7 1.7 3.1 1 1 1 3 3 3 0 Viral coat protein Arena_ncap_C PF17290.2 OWF51616.1 - 0.81 9.0 8.0 5.3 6.3 0.7 2.5 2 0 0 2 2 2 0 Arenavirus nucleocapsid C-terminal domain nsp9 PF08710.10 OWF51616.1 - 1.8 9.0 5.0 21 5.5 0.1 2.9 3 1 0 3 3 3 0 nsp9 replicase Mvb12 PF09452.10 OWF51617.1 - 0.0073 16.7 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 GerD PF17898.1 OWF51617.1 - 0.12 12.3 0.1 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Spore germination GerD central core domain TEP1_N PF05386.11 OWF51618.1 - 0.0094 15.5 14.6 7.6 6.2 0.2 6.7 8 0 0 8 8 8 3 TEP1 N-terminal domain DsrC PF04358.13 OWF51618.1 - 0.031 14.8 13.1 1.5 9.4 0.6 3.3 1 1 2 3 3 3 0 DsrC like protein AsiA PF09010.10 OWF51618.1 - 0.039 14.0 2.5 3.3 7.9 0.2 2.6 2 0 0 2 2 2 0 Anti-Sigma Factor A Methyltransf_31 PF13847.6 OWF51619.1 - 0.013 15.3 2.5 0.045 13.5 2.5 1.8 1 0 0 1 1 1 0 Methyltransferase domain MDH PF02315.16 OWF51620.1 - 0.044 13.9 0.1 1.2e+02 2.9 0.0 4.0 5 0 0 5 5 5 0 Methanol dehydrogenase beta subunit LRR_8 PF13855.6 OWF51621.1 - 1.2e-74 246.0 64.8 3.1e-14 52.5 11.1 7.5 4 1 3 7 7 7 7 Leucine rich repeat I-set PF07679.16 OWF51621.1 - 3.3e-52 174.5 0.1 2.3e-20 72.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF51621.1 - 5.7e-45 151.8 3.0 1.8e-13 50.9 0.0 4.1 4 0 0 4 4 3 3 Immunoglobulin domain LRR_4 PF12799.7 OWF51621.1 - 1.4e-34 117.5 69.0 1.7e-05 25.0 1.0 9.5 3 1 6 11 11 11 11 Leucine Rich repeats (2 copies) ig PF00047.25 OWF51621.1 - 2.1e-33 114.3 0.5 2.5e-10 40.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 OWF51621.1 - 4.4e-31 107.5 15.6 3.8e-13 49.5 1.3 4.5 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) Ig_2 PF13895.6 OWF51621.1 - 6.5e-30 103.3 0.2 1.3e-08 35.0 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain LRR_9 PF14580.6 OWF51621.1 - 1.4e-20 73.5 33.1 4e-07 29.7 1.2 5.2 1 1 4 5 5 5 5 Leucine-rich repeat V-set PF07686.17 OWF51621.1 - 9.4e-15 54.7 6.9 0.002 18.3 1.3 6.2 3 3 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF51621.1 - 6e-11 42.3 0.1 0.00075 19.5 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 OWF51621.1 - 1.6e-08 34.8 0.8 0.00025 21.3 0.1 3.8 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 OWF51621.1 - 3.7e-06 26.4 0.0 0.75 9.4 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF51621.1 - 7e-05 22.8 0.1 1.7 8.8 0.0 3.5 3 0 0 3 3 3 1 C17orf99 Ig domain LRR_1 PF00560.33 OWF51621.1 - 0.00011 22.2 49.5 2.3 9.1 0.5 14.0 15 1 0 15 15 14 3 Leucine Rich Repeat LRRNT PF01462.18 OWF51621.1 - 0.0011 18.6 2.6 0.0011 18.6 2.6 2.7 3 0 0 3 3 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 OWF51621.1 - 0.037 14.6 0.5 0.14 12.8 0.0 2.4 2 0 0 2 2 1 0 Leucine rich repeat C-terminal domain Receptor_2B4 PF11465.8 OWF51621.1 - 0.096 12.9 0.1 13 6.0 0.0 3.6 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 PRIMA1 PF16101.5 OWF51621.1 - 0.26 11.3 0.0 0.26 11.3 0.0 3.2 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 Y_phosphatase PF00102.27 OWF51622.1 - 7.7e-78 261.3 0.1 1.1e-77 260.7 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF51622.1 - 4.8e-06 26.7 0.1 9.1e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OWF51622.1 - 0.00013 21.8 1.1 0.0007 19.4 0.4 2.5 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF51622.1 - 0.00074 19.7 0.2 0.0052 16.9 0.0 2.4 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF1416 PF07210.12 OWF51623.1 - 3.6e-06 26.8 33.3 27 4.8 0.2 11.7 1 1 14 15 15 15 11 Protein of unknown function (DUF1416) Peptidase_S37 PF05576.11 OWF51623.1 - 0.00018 20.4 10.8 15 4.1 0.0 7.0 1 1 7 8 8 8 8 PS-10 peptidase S37 Castor_Poll_mid PF06241.12 OWF51624.1 - 0.072 13.1 1.8 2.8 7.9 0.1 2.7 2 1 1 3 3 3 0 Castor and Pollux, part of voltage-gated ion channel Baculo_gp41 PF04700.12 OWF51624.1 - 0.24 11.1 1.4 17 5.1 0.1 2.4 1 1 2 3 3 3 0 Structural glycoprotein p40/gp41 conserved region DUF3574 PF12098.8 OWF51624.1 - 6.8 6.5 6.4 1.2e+02 2.5 0.1 4.0 2 2 6 8 8 8 0 Protein of unknown function (DUF3574) Fer4_11 PF13247.6 OWF51625.1 - 0.088 12.9 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain 7tm_1 PF00001.21 OWF51626.1 - 1.9e-71 240.5 0.0 3e-71 239.8 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF51626.1 - 1.4e-08 34.9 6.8 1.4e-08 34.9 6.8 1.7 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF51626.1 - 5.4e-07 29.5 10.3 5.4e-07 29.5 10.3 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF51626.1 - 2.1e-06 27.3 5.7 2.1e-06 27.3 5.7 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 OWF51626.1 - 0.023 14.0 18.1 0.12 11.8 12.0 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF485 PF04341.12 OWF51626.1 - 0.38 10.7 2.8 0.9 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF485 7TM_GPCR_Srbc PF10316.9 OWF51626.1 - 0.91 9.0 15.1 0.022 14.3 7.9 1.9 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc RWP-RK PF02042.15 OWF51627.1 - 0.034 14.1 0.1 0.21 11.6 0.1 2.1 1 1 1 2 2 2 0 RWP-RK domain Nrf1_DNA-bind PF10491.9 OWF51628.1 - 5.4e-105 349.8 0.0 9.1e-105 349.0 0.0 1.4 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 VWA_2 PF13519.6 OWF51628.1 - 0.076 13.7 0.6 0.24 12.0 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain DnaJ_CXXCXGXG PF00684.19 OWF51629.1 - 9.4e-05 22.7 26.4 0.32 11.4 27.7 3.6 1 1 2 3 3 3 3 DnaJ central domain Roc PF08477.13 OWF51630.1 - 2.5e-05 24.5 0.0 5.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 OWF51630.1 - 0.021 15.4 0.6 0.055 14.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 OWF51630.1 - 0.026 14.6 0.8 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family Usp PF00582.26 OWF51631.1 - 6.1e-28 98.1 0.0 6.9e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 OWF51632.1 - 1.6e-24 87.0 0.0 1.8e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family 7tm_1 PF00001.21 OWF51634.1 - 4.7e-61 206.4 14.0 1e-60 205.3 14.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF51634.1 - 2.4e-11 43.5 14.9 8.9e-06 25.3 8.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF51634.1 - 6.3e-10 39.1 11.4 6.3e-10 39.1 11.4 1.8 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF51634.1 - 0.00028 20.7 8.7 0.00098 18.9 6.2 2.2 2 0 0 2 2 2 1 Olfactory receptor GWT1 PF06423.12 OWF51634.1 - 0.03 14.5 5.7 0.4 10.8 0.1 2.6 2 1 0 2 2 2 0 GWT1 Tetraspanin PF00335.20 OWF51634.1 - 0.81 9.4 6.5 3.4 7.3 6.5 2.2 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 OWF51634.1 - 1.1 9.7 6.5 2.8 8.4 3.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) TIMP PF00965.17 OWF51635.1 - 6.3e-40 136.9 3.6 7.2e-40 136.7 3.6 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 OWF51635.1 - 1.8e-06 27.7 0.3 1.1e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 UNC-6/NTR/C345C module AraC_binding PF02311.19 OWF51635.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Cadherin PF00028.17 OWF51636.1 - 1.3e-66 221.0 24.0 1.8e-17 63.6 0.0 7.8 7 1 0 7 7 7 7 Cadherin domain Cadherin_3 PF16184.5 OWF51636.1 - 2.8e-17 62.7 1.7 0.0065 16.5 0.0 5.9 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 OWF51636.1 - 0.00025 21.6 97.0 0.0088 16.7 6.1 8.0 5 2 1 7 7 7 5 Bacterial cadherin-like domain LT-IIB PF06453.11 OWF51636.1 - 0.057 13.3 3.4 0.64 9.9 0.3 3.6 3 0 0 3 3 3 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) TPT PF03151.16 OWF51638.1 - 1.2e-25 90.4 24.2 1.5e-25 90.2 24.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OWF51638.1 - 7e-08 32.7 28.0 2e-05 24.8 12.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family RRM_1 PF00076.22 OWF51639.1 - 1e-20 73.3 0.1 1.6e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF51639.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF51639.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCHC PF00098.23 OWF51639.1 - 2.2e-05 24.3 3.0 3.7e-05 23.6 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Limkain-b1 PF11608.8 OWF51639.1 - 0.00031 20.7 0.1 0.00079 19.4 0.1 1.7 1 0 0 1 1 1 1 Limkain b1 zf-CCHC_3 PF13917.6 OWF51639.1 - 0.0011 18.9 0.7 0.002 18.0 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_8 PF11835.8 OWF51639.1 - 0.0094 16.1 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 RRM-like domain DNA_topoisoIV PF00521.20 OWF51639.1 - 0.017 14.1 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RRM_7 PF16367.5 OWF51639.1 - 0.15 12.2 0.0 0.65 10.2 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif Pox_Ag35 PF03286.14 OWF51639.1 - 4.1 7.1 13.5 7.8 6.2 13.4 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 OWF51639.1 - 4.9 6.8 10.3 0.97 9.1 6.6 1.7 1 1 1 2 2 2 0 FAM176 family QVR PF17064.5 OWF51640.1 - 0.00043 20.5 9.4 0.0017 18.6 9.4 1.8 1 1 0 1 1 1 1 Sleepless protein UPAR_LY6_2 PF16975.5 OWF51640.1 - 0.55 10.4 7.2 0.047 13.9 2.4 1.6 2 0 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 EF-hand_7 PF13499.6 OWF51641.1 - 1.1e-11 45.0 1.2 1.7e-07 31.6 0.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF51641.1 - 4.8e-07 29.2 7.8 0.0019 18.0 0.9 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OWF51641.1 - 1.8e-05 24.0 10.0 0.0087 15.5 1.7 3.7 3 0 0 3 3 3 2 EF hand Caleosin PF05042.13 OWF51641.1 - 0.065 13.2 1.5 0.21 11.5 0.2 2.1 2 0 0 2 2 2 0 Caleosin related protein EF-hand_5 PF13202.6 OWF51641.1 - 0.37 10.4 3.2 14 5.4 0.3 2.8 2 0 0 2 2 2 0 EF hand ESSS PF10183.9 OWF51642.1 - 7e-16 58.3 0.0 9.5e-16 57.9 0.0 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FAM76 PF16046.5 OWF51643.1 - 0.01 15.2 16.7 0.019 14.3 16.7 1.4 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 OWF51643.1 - 0.26 10.1 13.4 0.45 9.3 13.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 OWF51643.1 - 0.45 9.0 29.1 0.92 8.0 29.1 1.4 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 OWF51643.1 - 0.83 9.7 17.2 1.7 8.7 17.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RAP1 PF07218.11 OWF51643.1 - 0.87 7.8 14.8 1.8 6.7 14.8 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.6 OWF51643.1 - 7.6 5.8 10.3 13 5.0 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DltD PF04914.12 OWF51644.1 - 0.0011 18.5 0.1 0.0012 18.3 0.1 1.1 1 0 0 1 1 1 1 DltD protein Siva PF05458.12 OWF51644.1 - 0.21 11.3 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) NUDIX PF00293.28 OWF51645.1 - 8.6e-13 48.5 0.0 1.9e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain Pkinase PF00069.25 OWF51646.1 - 1.7e-66 224.3 0.0 2.2e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51646.1 - 3.5e-32 111.7 0.0 4.7e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF51646.1 - 7.6e-09 35.3 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF51646.1 - 3.4e-06 26.2 0.1 1.2e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF51646.1 - 0.00028 20.3 0.2 0.00052 19.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OWF51646.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OWF51646.1 - 0.013 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family UAA PF08449.11 OWF51647.1 - 4.1e-94 315.2 16.8 4.6e-94 315.0 16.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OWF51647.1 - 0.00025 21.2 23.6 0.0035 17.5 6.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OWF51647.1 - 0.006 16.0 0.5 0.006 16.0 0.5 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family GWT1 PF06423.12 OWF51647.1 - 0.71 10.0 7.6 0.5 10.5 4.1 2.6 1 1 1 2 2 2 0 GWT1 Peptidase_C97 PF05903.14 OWF51648.1 - 0.062 13.1 2.1 0.12 12.2 2.1 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-RING_13 PF17977.1 OWF51649.1 - 0.0044 17.1 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Peptidase_S9 PF00326.21 OWF51650.1 - 9.7e-35 120.0 0.0 1.6e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OWF51650.1 - 9e-10 38.2 0.1 0.00037 19.8 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 OWF51650.1 - 1.2e-05 24.9 0.0 5.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OWF51650.1 - 7.3e-05 22.5 3.2 0.019 14.7 1.4 3.0 2 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF51650.1 - 0.001 19.7 3.5 0.0037 17.9 3.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 OWF51650.1 - 0.0011 17.8 0.2 0.035 12.8 0.2 2.7 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 OWF51650.1 - 0.0024 17.5 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 OWF51650.1 - 0.059 12.2 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Macro PF01661.21 OWF51652.1 - 8.2e-15 54.9 0.1 1.5e-11 44.4 0.0 3.3 3 0 0 3 3 3 2 Macro domain F5_F8_type_C PF00754.25 OWF51653.1 - 6.4e-11 42.5 0.9 1e-09 38.6 0.0 3.2 3 1 0 3 3 3 1 F5/8 type C domain Sid-5 PF17204.3 OWF51654.1 - 0.00078 19.6 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Sid-5 family TMEMspv1-c74-12 PF11044.8 OWF51654.1 - 0.019 15.0 0.5 0.033 14.2 0.5 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sigma_reg_N PF13800.6 OWF51654.1 - 0.068 13.5 0.9 0.27 11.5 0.0 2.5 2 1 1 3 3 3 0 Sigma factor regulator N-terminal EphA2_TM PF14575.6 OWF51654.1 - 0.099 13.5 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4083 PF13314.6 OWF51654.1 - 0.2 11.6 1.8 0.5 10.4 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) RIFIN PF02009.16 OWF51654.1 - 0.26 11.1 14.8 0.83 9.5 10.5 2.4 1 1 1 2 2 2 0 Rifin SKG6 PF08693.10 OWF51654.1 - 0.38 10.2 4.5 1.1 8.7 4.5 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3290 PF11694.8 OWF51654.1 - 1.9 8.4 4.8 8.7 6.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) FeoB_associated PF12669.7 OWF51654.1 - 2.3 8.7 3.8 4.3 7.8 3.8 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF5622 PF18533.1 OWF51655.1 - 0.19 11.9 1.4 0.44 10.7 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5622) COMM_domain PF07258.14 OWF51657.1 - 6.3e-17 61.5 0.0 2.2e-16 59.7 0.0 2.0 1 0 0 1 1 1 1 COMM domain WD40 PF00400.32 OWF51658.1 - 2.5e-12 47.1 13.5 0.00015 22.5 0.2 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF51658.1 - 0.00028 21.1 0.3 0.23 11.8 0.0 3.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF51658.1 - 0.011 14.4 2.4 0.048 12.3 0.8 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Usp PF00582.26 OWF51659.1 - 2.2e-27 96.3 0.0 3e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Lipocalin PF00061.23 OWF51660.1 - 0.075 13.2 12.7 0.041 14.1 2.0 3.7 2 1 1 3 3 3 0 Lipocalin / cytosolic fatty-acid binding protein family Ank_2 PF12796.7 OWF51661.1 - 1.9e-58 195.0 7.8 2.6e-14 53.5 0.1 5.0 3 1 3 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF51661.1 - 4.9e-39 132.2 4.6 1.3e-08 35.2 0.2 7.6 2 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF51661.1 - 8.9e-39 127.1 4.3 4.5e-07 29.7 0.1 8.9 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 OWF51661.1 - 7e-35 118.0 9.8 1.5e-06 28.4 0.4 8.3 7 1 1 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OWF51661.1 - 3.3e-30 103.8 3.9 4.8e-06 26.8 0.0 5.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) HEPN_DZIP3 PF18738.1 OWF51661.1 - 1e-26 93.4 0.0 4.3e-26 91.4 0.0 2.2 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN AAA_10 PF12846.7 OWF51661.1 - 0.0014 17.6 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Hpr_kinase_C PF07475.12 OWF51661.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain TrwB_AAD_bind PF10412.9 OWF51661.1 - 0.086 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 OWF51661.1 - 0.14 12.5 0.0 0.69 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 OWF51661.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Peptidase_C48 PF02902.19 OWF51662.1 - 2.1e-10 40.8 0.0 5.8e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 OWF51662.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain UDG PF03167.19 OWF51663.1 - 1.6e-20 73.7 0.0 3.4e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF4516 PF14990.6 OWF51664.1 - 5.7e-07 29.1 0.0 7.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) Trp_syntA PF00290.20 OWF51664.1 - 0.016 14.1 0.0 0.017 14.0 0.0 1.0 1 0 0 1 1 1 0 Tryptophan synthase alpha chain ABC2_membrane_3 PF12698.7 OWF51665.1 - 4e-67 226.8 47.0 1.4e-43 149.4 26.2 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 OWF51665.1 - 3e-52 176.8 0.1 2.3e-26 92.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OWF51665.1 - 2.2e-21 77.0 3.2 1.8e-07 31.3 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 OWF51665.1 - 1.3e-05 25.8 0.0 0.063 14.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SMC_N PF02463.19 OWF51665.1 - 0.00011 21.7 1.0 8.8 5.7 0.1 4.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OWF51665.1 - 0.01 15.6 0.0 1.3 8.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 OWF51665.1 - 0.015 15.7 0.0 3.4 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 OWF51665.1 - 0.016 15.4 0.0 6.9 7.0 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 OWF51665.1 - 0.023 14.6 0.8 2.5 8.0 0.2 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 OWF51665.1 - 0.032 14.7 11.0 0.12 12.9 1.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 OWF51665.1 - 0.032 14.0 3.1 0.55 10.0 0.5 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OWF51665.1 - 0.063 13.0 0.0 6.9 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OWF51665.1 - 0.067 13.3 0.1 20 5.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF51665.1 - 0.075 13.3 0.1 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 OWF51665.1 - 0.12 12.2 3.0 0.11 12.2 0.6 2.1 2 0 0 2 2 2 0 MukB N-terminal Zeta_toxin PF06414.12 OWF51665.1 - 0.13 11.6 0.0 9.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin LAP2alpha PF11560.8 OWF51665.1 - 0.19 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha SRP54 PF00448.22 OWF51665.1 - 0.75 9.4 3.7 2.1 8.0 0.7 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PNTB PF02233.16 OWF51665.1 - 2.1 7.1 5.5 4.4 6.1 5.5 1.4 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit ABC2_membrane_3 PF12698.7 OWF51666.1 - 6.5e-73 245.8 55.9 8e-42 143.6 26.9 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 OWF51666.1 - 3.5e-52 176.5 0.1 2.7e-27 96.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OWF51666.1 - 3.9e-21 76.1 0.1 9.1e-08 32.2 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF51666.1 - 5.1e-05 23.9 3.9 0.02 15.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 OWF51666.1 - 0.0003 20.3 0.0 4.4 6.7 0.1 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OWF51666.1 - 0.00064 19.9 0.0 1.5 9.1 0.0 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 OWF51666.1 - 0.0014 18.4 0.2 0.63 9.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 OWF51666.1 - 0.0014 17.9 0.0 0.67 9.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF4162 PF13732.6 OWF51666.1 - 0.0016 19.1 0.1 0.71 10.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 OWF51666.1 - 0.0023 17.7 0.0 0.095 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain MukB PF04310.12 OWF51666.1 - 0.012 15.4 1.6 0.096 12.5 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal Sterile PF03015.19 OWF51666.1 - 0.014 15.6 0.0 0.41 10.9 0.0 2.8 2 0 0 2 2 2 0 Male sterility protein Rad17 PF03215.15 OWF51666.1 - 0.017 15.0 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 OWF51666.1 - 0.018 14.7 0.7 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OWF51666.1 - 0.019 14.7 3.5 0.47 10.2 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 OWF51666.1 - 0.047 13.3 2.1 1.9 8.1 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 OWF51666.1 - 0.062 13.2 1.5 0.87 9.5 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_27 PF13514.6 OWF51666.1 - 0.069 12.7 0.6 0.87 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OWF51666.1 - 0.12 12.7 1.8 5.1 7.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OWF51666.1 - 0.13 11.4 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RabGAP-TBC PF00566.18 OWF51666.1 - 0.15 11.7 1.2 0.38 10.4 1.2 1.6 1 0 0 1 1 1 0 Rab-GTPase-TBC domain MMR_HSR1 PF01926.23 OWF51666.1 - 2.4 8.3 4.7 65 3.6 0.1 3.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase Glyco_hydro_47 PF01532.20 OWF51667.1 - 5.5e-117 391.5 0.0 1.1e-116 390.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 WBP-1 PF11669.8 OWF51670.1 - 0.0045 17.6 6.0 0.046 14.4 6.0 2.4 1 1 0 1 1 1 1 WW domain-binding protein 1 OPT PF03169.15 OWF51670.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Shisa PF13908.6 OWF51670.1 - 0.21 11.8 23.9 0.068 13.4 2.1 2.5 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Fasciclin PF02469.22 OWF51672.1 - 1.9e-63 212.4 1.3 8.1e-17 61.6 0.1 4.2 4 0 0 4 4 4 4 Fasciclin domain EGF_3 PF12947.7 OWF51672.1 - 1.3e-39 134.0 239.7 6.1e-08 32.7 9.3 16.2 15 2 0 15 15 15 10 EGF domain FXa_inhibition PF14670.6 OWF51672.1 - 0.00028 21.1 10.3 0.00028 21.1 10.3 17.1 13 4 4 17 17 17 5 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 OWF51672.1 - 0.013 15.8 14.6 0.013 15.8 14.6 17.5 15 3 2 17 17 17 0 EGF-like domain PTN_MK_C PF01091.18 OWF51673.1 - 4e-19 68.8 36.6 3.4e-07 30.5 2.5 4.5 1 1 3 4 4 4 4 PTN/MK heparin-binding protein family, C-terminal domain BTG PF07742.12 OWF51673.1 - 0.00082 19.2 1.1 0.96 9.3 0.1 2.2 2 0 0 2 2 2 2 BTG family RRXRR PF14239.6 OWF51673.1 - 0.0029 17.5 5.1 0.13 12.1 4.7 2.4 2 0 0 2 2 2 1 RRXRR protein Med19 PF10278.9 OWF51673.1 - 0.036 14.0 10.5 0.062 13.2 10.5 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CNDH2_C PF16858.5 OWF51673.1 - 0.075 12.9 5.0 0.12 12.2 5.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TIP41 PF04176.13 OWF51675.1 - 3.4e-65 218.7 3.2 4.3e-65 218.4 3.2 1.1 1 0 0 1 1 1 1 TIP41-like family WD40 PF00400.32 OWF51676.1 - 1.3e-24 85.9 7.0 5.8e-05 23.8 0.5 7.0 7 0 0 7 7 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF51676.1 - 1.4e-10 41.3 0.0 0.006 16.9 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 OWF51676.1 - 8e-08 31.8 4.1 0.024 14.8 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF51676.1 - 2.2e-06 27.2 7.7 0.0012 18.5 0.4 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF51676.1 - 8.2e-05 23.0 0.3 0.00033 21.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF51676.1 - 0.00061 20.0 2.6 0.0018 18.4 2.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OWF51676.1 - 0.0014 19.3 1.2 1.2 10.1 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF51676.1 - 0.0015 18.1 2.9 0.075 12.7 0.5 2.6 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 OWF51676.1 - 0.0023 18.0 0.7 0.0075 16.4 0.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF51676.1 - 0.0039 17.5 1.3 0.24 11.8 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF51676.1 - 0.023 15.4 0.5 15 6.3 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF51676.1 - 0.027 14.8 3.5 3.4 8.0 0.8 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF51676.1 - 0.11 13.2 0.4 18 6.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CRAL_TRIO_2 PF13716.6 OWF51677.1 - 1.3e-32 112.9 2.3 1.8e-32 112.4 1.3 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Macro PF01661.21 OWF51677.1 - 1.4e-17 63.8 0.0 3.3e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.20 OWF51677.1 - 1.1e-10 41.5 0.5 2.5e-10 40.3 0.5 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain PGA_cap PF09587.10 OWF51677.1 - 0.057 12.9 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap RNase_T PF00929.24 OWF51679.1 - 0.033 14.7 0.0 0.098 13.2 0.0 1.8 1 0 0 1 1 1 0 Exonuclease STb_secrete PF09075.10 OWF51680.1 - 5.2e-05 23.2 25.2 20 5.3 0.2 7.7 1 1 12 13 13 13 13 Heat-stable enterotoxin B, secretory Tachystatin_B PF11478.8 OWF51680.1 - 0.0082 16.1 23.3 1.2e+02 2.7 0.1 10.4 1 1 12 13 13 13 0 Antimicrobial chitin binding protein tachystatin B Perilipin PF03036.16 OWF51680.1 - 0.13 11.3 0.0 3.9 6.4 0.0 2.6 1 1 0 1 1 1 0 Perilipin family Med14 PF08638.11 OWF51681.1 - 0.028 13.8 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 Methyltransf_7 PF03492.15 OWF51681.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Extensin_1 PF02095.15 OWF51683.1 - 0.0039 17.3 2.0 1.8e+02 2.7 0.0 5.7 6 0 0 6 6 6 0 Extensin-like protein repeat Ribosomal_L44 PF00935.19 OWF51684.1 - 2.4e-34 117.6 13.1 4e-34 116.9 13.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 LRV_FeS PF05484.11 OWF51684.1 - 1.9 8.5 5.1 0.57 10.2 0.6 2.0 2 0 0 2 2 2 0 LRV protein FeS4 cluster IF-2B PF01008.17 OWF51685.1 - 1.5e-75 254.1 0.0 2.4e-75 253.4 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family LAP1C PF05609.12 OWF51685.1 - 1.5 7.8 12.2 2.1 7.4 12.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ADK PF00406.22 OWF51686.1 - 6.5e-58 195.1 0.0 8.1e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OWF51686.1 - 1.5e-23 83.7 0.0 4.2e-23 82.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 OWF51686.1 - 1.6e-17 63.1 0.0 6.7e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 OWF51686.1 - 0.0048 17.1 0.0 0.025 14.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain Hydin_ADK PF17213.3 OWF51686.1 - 0.016 15.5 0.2 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 OWF51686.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase GFD1 PF17331.2 OWF51686.1 - 0.024 14.8 0.9 0.05 13.8 0.9 1.4 1 0 0 1 1 1 0 GFD1 mRNA transport factor AAA_18 PF13238.6 OWF51686.1 - 0.051 14.1 0.0 0.19 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 OWF51686.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNX17_FERM_C PF18116.1 OWF51687.1 - 8.7e-38 128.7 0.1 2.2e-37 127.4 0.0 1.7 2 0 0 2 2 2 1 Sorting Nexin 17 FERM C-terminal domain PX PF00787.24 OWF51687.1 - 1.3e-11 44.5 1.2 3e-11 43.3 1.2 1.7 1 0 0 1 1 1 1 PX domain RA PF00788.23 OWF51687.1 - 0.0022 18.6 0.0 0.0051 17.4 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 OWF51687.1 - 0.018 15.0 0.1 0.047 13.6 0.1 1.9 1 1 0 1 1 1 0 FERM N-terminal domain FERM_M PF00373.18 OWF51687.1 - 0.13 12.7 0.4 4.5 7.7 0.1 2.6 1 1 1 2 2 2 0 FERM central domain BPL_LplA_LipB PF03099.19 OWF51688.1 - 2.7e-05 24.1 0.0 0.00073 19.4 0.0 2.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SAPS PF04499.15 OWF51689.1 - 0.0069 15.2 12.2 0.0091 14.8 12.2 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein PWI PF01480.17 OWF51689.1 - 0.038 14.3 1.9 1.5 9.2 1.9 2.4 1 1 0 1 1 1 0 PWI domain DUF572 PF04502.13 OWF51689.1 - 2.5 7.6 24.5 3.4 7.2 24.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) GET2 PF08690.10 OWF51689.1 - 4.1 7.0 13.2 0.38 10.4 1.7 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 SRP-alpha_N PF04086.13 OWF51689.1 - 5.6 6.8 23.5 6.9 6.5 23.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Cytomega_UL84 PF06284.11 OWF51689.1 - 7.8 4.8 7.6 14 4.0 7.6 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Thioredoxin PF00085.20 OWF51690.1 - 9.1e-66 218.3 0.0 1.9e-31 108.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OWF51690.1 - 7.7e-10 39.0 0.0 1.6e-07 31.4 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OWF51690.1 - 6.1e-07 29.9 1.4 0.48 10.9 0.1 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OWF51690.1 - 1.4e-05 25.3 0.0 0.3 11.4 0.0 3.5 3 2 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 OWF51690.1 - 9.1e-05 21.9 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 OWF51690.1 - 0.001 19.1 0.0 0.9 9.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 OWF51690.1 - 0.0011 18.8 0.0 0.85 9.5 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 OWF51690.1 - 0.0047 17.1 0.9 4.8 7.4 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_4 PF13462.6 OWF51690.1 - 0.035 14.3 0.2 2.8 8.1 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin Alk_phosphatase PF00245.20 OWF51691.1 - 2.8e-137 458.1 0.0 3.2e-137 457.9 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF51691.1 - 0.00028 20.3 0.0 0.00046 19.6 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily MAM PF00629.23 OWF51692.1 - 1.9e-161 531.7 0.2 1.9e-32 112.4 0.0 5.5 5 0 0 5 5 5 5 MAM domain, meprin/A5/mu Astacin PF01400.24 OWF51692.1 - 1.7e-30 106.0 1.1 5.8e-27 94.5 1.1 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF PF00008.27 OWF51692.1 - 6.1e-22 77.6 98.4 1.9e-05 24.8 9.5 8.1 7 0 0 7 7 7 6 EGF-like domain CUB PF00431.20 OWF51692.1 - 9.4e-10 38.8 0.0 2.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 CUB domain hEGF PF12661.7 OWF51692.1 - 7.8e-08 32.7 97.7 0.0014 19.2 5.7 8.7 8 0 0 8 8 8 5 Human growth factor-like EGF EGF_2 PF07974.13 OWF51692.1 - 4.9e-07 30.0 123.0 0.063 13.7 10.1 8.0 7 0 0 7 7 7 6 EGF-like domain MAM PF00629.23 OWF51693.1 - 1.2e-112 373.1 0.0 3.9e-29 101.6 0.0 4.2 4 0 0 4 4 4 4 MAM domain, meprin/A5/mu EGF PF00008.27 OWF51693.1 - 2.9e-09 37.1 42.7 8.9e-05 22.7 5.7 4.5 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 OWF51693.1 - 0.6 10.8 41.8 0.037 14.7 6.4 5.5 4 2 2 6 6 6 0 Human growth factor-like EGF EGF_2 PF07974.13 OWF51693.1 - 1.4 9.3 53.1 0.23 11.9 8.8 4.4 4 0 0 4 4 4 0 EGF-like domain Lectin_C PF00059.21 OWF51694.1 - 1.7e-07 32.0 0.5 6.9e-07 30.0 0.1 2.0 1 1 1 2 2 2 1 Lectin C-type domain UPF0122 PF04297.14 OWF51694.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like YjbE PF11106.8 OWF51694.1 - 9.6 6.5 6.4 17 5.7 6.4 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Lectin_C PF00059.21 OWF51695.1 - 4.9e-08 33.7 0.5 1.4e-07 32.2 0.1 1.9 1 1 1 2 2 2 1 Lectin C-type domain UPF0122 PF04297.14 OWF51695.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like YjbE PF11106.8 OWF51695.1 - 5.3 7.3 7.5 9.5 6.5 7.5 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Hormone_5 PF00184.17 OWF51696.1 - 1.3e-19 70.8 29.1 1.3e-19 70.8 29.1 1.7 2 1 0 2 2 2 1 Neurohypophysial hormones, C-terminal Domain Macro PF01661.21 OWF51697.1 - 1.5e-46 157.3 4.9 2e-17 63.3 0.1 3.7 3 0 0 3 3 3 3 Macro domain PARP PF00644.20 OWF51697.1 - 2.1e-24 86.2 0.8 1e-23 84.0 0.8 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 OWF51697.1 - 0.00033 21.2 0.2 0.00098 19.7 0.2 1.8 1 0 0 1 1 1 1 WWE domain NID PF07292.13 OWF51698.1 - 4.6e-05 24.0 0.7 1.4 9.6 0.0 4.8 4 0 0 4 4 4 2 Nmi/IFP 35 domain (NID) RRM_1 PF00076.22 OWF51698.1 - 0.0027 17.5 0.2 5.6 6.9 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 OWF51700.1 - 5.8e-05 23.3 1.5 0.0066 16.7 0.0 4.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PAP2 PF01569.21 OWF51701.1 - 1.9e-30 105.4 1.6 1.9e-30 105.4 1.6 1.6 2 0 0 2 2 2 1 PAP2 superfamily EamA PF00892.20 OWF51701.1 - 0.043 14.0 2.7 4.2 7.5 0.2 2.5 2 1 0 2 2 2 0 EamA-like transporter family MNHE PF01899.16 OWF51701.1 - 0.067 12.9 1.0 1 9.1 0.2 2.4 2 1 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF5510 PF17629.2 OWF51701.1 - 0.17 11.8 1.7 0.56 10.2 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5510) DUF2339 PF10101.9 OWF51701.1 - 0.3 9.6 3.7 0.57 8.7 1.1 1.8 1 1 0 2 2 2 0 Predicted membrane protein (DUF2339) PAP2_3 PF14378.6 OWF51701.1 - 0.49 10.1 9.2 7.7 6.2 9.2 2.5 1 1 0 1 1 1 0 PAP2 superfamily DUF4131 PF13567.6 OWF51701.1 - 3.4 7.3 9.5 8.7 6.0 2.8 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) ANAPC4_WD40 PF12894.7 OWF51702.1 - 5.6e-27 93.9 0.7 3.6e-05 24.0 0.0 6.6 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF51702.1 - 8.7e-26 89.7 13.2 6e-05 23.7 0.0 7.0 6 1 1 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 OWF51702.1 - 2.4e-10 40.6 0.0 3e-06 27.3 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OWF51702.1 - 6.7e-05 22.7 0.2 0.0067 16.3 0.0 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 OWF51702.1 - 0.00043 18.4 0.0 0.011 13.8 0.0 2.3 1 1 1 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 OWF51702.1 - 0.0029 16.6 0.1 0.78 8.6 0.0 3.4 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OWF51702.1 - 0.0043 15.8 0.0 0.0074 15.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 OWF51702.1 - 0.0086 14.9 2.8 3.2 6.4 0.0 3.3 2 1 2 4 4 4 2 Prolyl oligopeptidase, N-terminal beta-propeller domain WD40_like PF17005.5 OWF51702.1 - 0.01 15.2 0.0 0.094 12.0 0.0 2.3 2 1 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 OWF51702.1 - 0.011 14.3 0.0 0.23 9.9 0.0 2.4 1 1 2 3 3 3 0 Cytochrome D1 heme domain Frtz PF11768.8 OWF51702.1 - 0.087 11.1 0.0 2.3 6.4 0.0 2.3 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 OWF51702.1 - 0.16 10.4 1.1 0.64 8.3 0.3 2.0 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family RAB3GAP2_N PF14655.6 OWF51702.1 - 0.19 11.0 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SH3_2 PF07653.17 OWF51703.1 - 8.5e-23 79.8 0.0 6e-11 41.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 OWF51703.1 - 9.3e-17 60.6 0.1 7.2e-09 35.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OWF51703.1 - 5.8e-08 32.2 0.0 0.0052 16.4 0.0 3.0 3 0 0 3 3 3 2 SH3 domain DUF2838 PF10998.8 OWF51704.1 - 1.4e-32 112.2 11.9 1.4e-32 112.2 11.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) VacA2 PF03077.14 OWF51705.1 - 0.00015 21.6 7.3 2.1 8.3 1.9 3.5 1 1 2 3 3 3 3 Putative vacuolating cytotoxin DUF2953 PF11167.8 OWF51705.1 - 0.017 15.2 6.3 12 6.1 2.1 4.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2953) DUF3887 PF13026.6 OWF51705.1 - 0.87 10.4 7.7 32 5.4 2.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3887) PTP_N PF12453.8 OWF51705.1 - 5.2 6.9 13.8 2.4e+02 1.5 0.1 6.2 7 0 0 7 7 7 0 Protein tyrosine phosphatase N terminal Chitin_synth_2 PF03142.15 OWF51706.1 - 2.6e-31 108.8 25.2 9.5e-30 103.7 0.0 5.0 4 1 1 5 5 5 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF51706.1 - 3.3e-11 43.5 5.6 3.3e-11 43.5 5.6 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF51706.1 - 6.8e-11 42.5 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF51706.1 - 0.0076 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3007 PF11460.8 OWF51706.1 - 0.076 13.3 0.1 0.43 10.9 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) EOS1 PF12326.8 OWF51706.1 - 0.12 12.4 2.0 0.53 10.2 0.6 2.6 2 0 0 2 2 2 0 N-glycosylation protein DUF2489 PF10675.9 OWF51706.1 - 8.5 6.3 6.4 9.6 6.1 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) EF-hand_7 PF13499.6 OWF51708.1 - 7.7e-11 42.3 2.6 3.5e-06 27.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF51708.1 - 4.8e-08 32.3 7.1 7.7e-06 25.4 0.2 3.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 OWF51708.1 - 4.9e-06 25.7 0.8 4.9e-06 25.7 0.8 3.3 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 OWF51708.1 - 0.00013 21.2 3.1 0.00014 21.2 0.5 2.3 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 OWF51708.1 - 0.0008 19.4 0.1 0.26 11.3 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 OWF51708.1 - 0.011 16.0 0.0 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 OWF51708.1 - 0.041 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Dockerin type I domain DUF4851 PF16143.5 OWF51708.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4851) DDHD PF02862.17 OWF51709.1 - 2.7e-53 181.4 0.8 4.6e-52 177.4 0.0 2.4 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 OWF51709.1 - 4.9e-07 30.3 1.3 0.0031 18.1 0.5 2.7 2 0 0 2 2 2 2 WWE domain SAM_1 PF00536.30 OWF51709.1 - 7.6e-06 26.3 0.2 1.5e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF747 PF05346.11 OWF51710.1 - 3.9e-103 345.3 18.7 6.4e-103 344.6 18.7 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family fn3_5 PF06280.12 OWF51710.1 - 0.028 15.1 0.5 0.059 14.1 0.5 1.5 1 0 0 1 1 1 0 Fn3-like domain Glutaredoxin PF00462.24 OWF51711.1 - 2.1e-41 139.9 0.1 1.3e-18 67.0 0.0 4.0 3 1 1 4 4 4 2 Glutaredoxin Thioredoxin PF00085.20 OWF51711.1 - 5.1e-16 58.5 0.1 1.5e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OWF51711.1 - 3.8e-07 30.5 0.0 2.5e-05 24.7 0.0 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain DIM1 PF02966.16 OWF51711.1 - 1.1e-05 25.3 0.0 2.9e-05 23.9 0.0 1.7 1 1 1 2 2 2 1 Mitosis protein DIM1 SH3BGR PF04908.15 OWF51711.1 - 1.1e-05 25.5 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein HyaE PF07449.11 OWF51711.1 - 1.9e-05 24.6 0.3 0.00087 19.2 0.1 3.4 3 2 1 4 4 4 1 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.6 OWF51711.1 - 7.9e-05 23.0 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain RdRP PF05183.12 OWF51711.1 - 0.0095 14.6 0.0 2.4 6.7 0.0 2.2 1 1 1 2 2 2 2 RNA dependent RNA polymerase Thioredoxin_8 PF13905.6 OWF51711.1 - 0.016 15.5 0.1 1.8 8.9 0.0 3.1 2 1 1 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 OWF51711.1 - 0.033 13.6 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 OWF51711.1 - 0.056 13.5 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain Fumerase_C PF05683.12 OWF51711.1 - 0.068 12.5 0.0 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 Fumarase C-terminus Thioredoxin_7 PF13899.6 OWF51711.1 - 0.086 13.0 0.1 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like DUF5381 PF17353.2 OWF51711.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Ribosomal_L36 PF00444.18 OWF51712.1 - 2.4e-09 37.2 14.0 1.1e+02 3.1 0.0 13.6 15 0 0 15 15 15 0 Ribosomal protein L36 Pullulanase_Ins PF18494.1 OWF51712.1 - 3.8e-06 27.3 37.1 1.4 9.5 0.3 9.0 1 1 11 12 12 12 8 Pullulanase Ins domain Glyco_transf_24 PF18404.1 OWF51712.1 - 2e-05 24.2 4.4 26 4.1 0.0 5.4 1 1 4 5 5 5 5 Glucosyltransferase 24 Peptidase_M55 PF04951.13 OWF51712.1 - 0.2 11.0 3.6 47 3.2 0.1 3.2 1 1 4 5 5 5 0 D-aminopeptidase Cys_box PF17869.1 OWF51712.1 - 1.1 9.5 37.7 8.5 6.6 3.5 6.2 1 1 5 6 6 6 0 Anosmin cysteine rich domain DUF4060 PF13269.6 OWF51713.1 - 0.28 11.3 1.2 10 6.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) PP1c_bdg PF10488.9 OWF51714.1 - 0.0063 16.0 4.2 1.1 8.6 0.1 3.0 1 1 2 3 3 3 3 Phosphatase-1 catalytic subunit binding region DYW_deaminase PF14432.6 OWF51715.1 - 0.13 12.1 0.0 1.8 8.4 0.0 2.0 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases Pentapeptide PF00805.22 OWF51716.1 - 4.6e-11 42.1 0.0 0.047 13.3 0.0 5.4 6 1 0 6 6 6 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OWF51716.1 - 3.8e-06 27.0 0.0 0.73 10.0 0.0 3.2 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Glucodextran_N PF09137.11 OWF51716.1 - 0.24 10.9 0.1 3.7 7.0 0.0 2.3 1 1 1 2 2 2 0 Glucodextranase, domain N IGFL PF14653.6 OWF51716.1 - 2 8.4 9.6 8.1 6.5 0.7 3.0 2 1 1 3 3 3 0 Insulin growth factor-like family DUF1435 PF07256.12 OWF51716.1 - 4.5 7.5 8.7 24 5.1 0.1 3.9 2 2 1 5 5 5 0 Protein of unknown function (DUF1435) Pentapeptide PF00805.22 OWF51717.1 - 7.6e-10 38.3 0.0 0.005 16.5 0.0 3.1 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OWF51717.1 - 0.00034 20.7 0.0 0.13 12.5 0.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Reticulon PF02453.17 OWF51718.1 - 0.0083 16.1 18.7 0.77 9.7 18.7 2.5 1 1 0 1 1 1 1 Reticulon DUF639 PF04842.12 OWF51718.1 - 0.035 13.5 0.9 0.061 12.7 0.9 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Tubulin PF00091.25 OWF51719.1 - 1.9e-70 237.1 0.0 3.3e-70 236.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF51719.1 - 4e-48 162.7 0.4 6.8e-48 162.0 0.4 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OWF51719.1 - 3.4e-05 24.1 0.0 9.4e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OWF51719.1 - 0.00053 19.3 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 OWF51719.1 - 0.032 13.9 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain Aldo_ket_red PF00248.21 OWF51720.1 - 1.9e-46 158.6 0.0 2.2e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Nucleos_tra2_C PF07662.13 OWF51721.1 - 3.1e-57 193.8 4.0 3.1e-57 193.8 4.0 2.8 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF51721.1 - 7.4e-23 81.0 7.4 7.4e-23 81.0 7.4 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Nucleos_tra2_C PF07662.13 OWF51722.1 - 1.1e-57 195.2 6.2 1.1e-57 195.2 6.2 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF51722.1 - 2e-21 76.4 6.8 2e-21 76.4 6.8 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus zf-CCHH PF10283.9 OWF51723.1 - 5.6e-23 80.6 7.3 8.1e-12 44.9 0.2 2.5 2 0 0 2 2 2 2 PBZ domain PARP PF00644.20 OWF51723.1 - 5.8e-15 55.4 1.1 2.4e-13 50.1 0.0 2.7 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain BRCT_2 PF16589.5 OWF51723.1 - 0.0032 17.8 0.0 0.0077 16.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OWF51723.1 - 0.014 15.7 0.4 0.24 11.8 0.0 2.8 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain DUF4600 PF15372.6 OWF51723.1 - 0.027 14.9 4.9 0.24 11.9 5.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF2115 PF09888.9 OWF51723.1 - 0.094 13.2 1.5 0.2 12.2 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) zf-CCCH PF00642.24 OWF51723.1 - 0.52 10.3 10.1 0.4 10.7 1.2 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FapA PF03961.13 OWF51723.1 - 0.62 8.6 6.7 0.93 8.0 6.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-CCCH_2 PF14608.6 OWF51723.1 - 7.5 7.2 7.9 29 5.3 0.7 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Methyltransf_31 PF13847.6 OWF51724.1 - 6.6e-25 87.7 0.0 9.8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF51724.1 - 1.3e-18 67.5 0.0 2.4e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF51724.1 - 4.7e-18 65.6 0.0 1.1e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF51724.1 - 2e-15 57.3 0.0 3.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF51724.1 - 1.3e-11 44.6 0.0 1.9e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF51724.1 - 2.2e-10 40.3 0.0 4.7e-10 39.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OWF51724.1 - 8e-09 35.1 0.1 1.2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 OWF51724.1 - 7.1e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OWF51724.1 - 2.2e-06 27.3 0.0 5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 OWF51724.1 - 4.9e-05 22.9 0.0 6.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OWF51724.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OWF51724.1 - 0.00017 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 OWF51724.1 - 0.00036 21.5 0.0 0.001 20.1 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OWF51724.1 - 0.003 17.3 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OWF51724.1 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DREV PF05219.12 OWF51724.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase GidB PF02527.15 OWF51724.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 OWF51725.1 - 6.4e-24 84.5 0.0 7.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF51725.1 - 3.3e-16 59.7 0.0 5.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF51725.1 - 4.5e-16 59.3 0.0 1.1e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF51725.1 - 1.1e-14 55.0 0.0 1.9e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF51725.1 - 5.2e-13 49.2 0.0 7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF51725.1 - 5.9e-10 38.9 0.0 8.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OWF51725.1 - 1.5e-06 27.7 0.0 1.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 OWF51725.1 - 6.9e-06 25.6 0.0 0.00011 21.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 OWF51725.1 - 2.4e-05 24.0 0.0 3.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 OWF51725.1 - 0.0021 19.0 0.0 0.0036 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OWF51725.1 - 0.0026 17.2 0.1 0.0052 16.2 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 OWF51725.1 - 0.027 14.6 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 OWF51725.1 - 0.081 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_16 PF10294.9 OWF51725.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase TPMT PF05724.11 OWF51725.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) p450 PF00067.22 OWF51726.1 - 3.3e-98 329.4 0.2 5.7e-98 328.7 0.2 1.3 1 1 0 1 1 1 1 Cytochrome P450 SWIM PF04434.17 OWF51727.1 - 0.015 14.9 2.0 0.036 13.8 2.0 1.7 1 0 0 1 1 1 0 SWIM zinc finger Pyr_redox_2 PF07992.14 OWF51728.1 - 1e-18 67.6 0.2 7.9e-10 38.4 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF51728.1 - 0.0012 18.6 1.3 0.12 11.9 1.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OWF51728.1 - 0.0017 18.4 0.1 0.8 9.7 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OWF51728.1 - 0.004 16.3 0.1 0.0075 15.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OWF51728.1 - 0.018 14.3 1.0 0.56 9.4 0.2 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF51728.1 - 0.018 15.6 2.1 0.12 12.9 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF51728.1 - 0.028 13.5 0.2 0.048 12.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 OWF51728.1 - 0.16 12.2 0.8 0.43 10.8 0.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OWF51728.1 - 0.24 10.7 3.2 6.9 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase CARD PF00619.21 OWF51729.1 - 2.4e-11 43.5 0.7 8e-11 41.8 0.7 2.0 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF51729.1 - 3.4e-06 26.9 0.1 1.2e-05 25.2 0.1 2.0 1 0 0 1 1 1 1 Caspase recruitment domain Metal_resist PF13801.6 OWF51729.1 - 0.28 11.4 2.2 0.33 11.1 0.0 2.2 3 0 0 3 3 3 0 Heavy-metal resistance PNISR PF15996.5 OWF51729.1 - 0.57 10.4 21.7 1.5 9.1 21.4 1.9 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR CDT1_C PF16679.5 OWF51729.1 - 9.1 6.8 9.7 7.2 7.1 0.3 3.3 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain ODC_AZ PF02100.17 OWF51730.1 - 6.9e-21 74.4 0.0 2.2e-20 72.7 0.0 1.7 1 1 1 2 2 2 1 Ornithine decarboxylase antizyme COX7C PF02935.16 OWF51731.1 - 2.6e-10 40.4 0.4 3.2e-10 40.1 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc MASE2 PF05230.11 OWF51731.1 - 0.027 14.5 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 MASE2 domain SH3_2 PF07653.17 OWF51732.1 - 0.058 13.1 0.0 25 4.7 0.0 4.5 3 2 0 3 3 3 0 Variant SH3 domain MF_alpha PF04648.12 OWF51732.1 - 0.13 12.6 8.2 1e+02 3.4 0.0 6.6 6 0 0 6 6 6 0 Yeast mating factor alpha hormone Gal-3-0_sulfotr PF06990.11 OWF51733.1 - 5.1e-50 170.5 6.3 8.5e-50 169.8 6.3 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Acetyltransf_10 PF13673.7 OWF51734.1 - 3.5e-09 36.7 0.0 8.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF51734.1 - 3.8e-08 33.6 0.0 7.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF51734.1 - 2.5e-07 31.0 0.0 5.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD PF00628.29 OWF51734.1 - 0.00011 22.0 3.0 0.00023 21.0 3.0 1.6 1 0 0 1 1 1 1 PHD-finger Acetyltransf_9 PF13527.7 OWF51734.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD_2 PF13831.6 OWF51734.1 - 0.04 13.5 0.3 0.092 12.3 0.3 1.6 1 0 0 1 1 1 0 PHD-finger FR47 PF08445.10 OWF51734.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein FANCL_C PF11793.8 OWF51734.1 - 0.24 11.6 1.8 0.49 10.6 1.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DEAD_2 PF06733.15 OWF51735.1 - 3.5e-54 183.1 3.8 9.4e-54 181.7 3.8 1.8 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 OWF51735.1 - 3.7e-42 144.4 0.5 1.6e-41 142.4 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.29 OWF51735.1 - 1.1e-06 28.6 0.2 0.00025 20.8 0.1 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 OWF51735.1 - 1.2e-05 25.4 4.0 0.019 14.9 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Pkinase PF00069.25 OWF51735.1 - 0.033 13.6 0.0 0.095 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein kinase domain LIN52 PF10044.9 OWF51735.1 - 0.46 11.2 2.4 40 5.0 0.1 3.4 3 0 0 3 3 3 0 Retinal tissue protein Stathmin PF00836.19 OWF51736.1 - 4.7e-50 169.1 37.7 9e-35 119.6 9.4 3.1 2 1 1 3 3 3 3 Stathmin family DUF4946 PF16304.5 OWF51736.1 - 0.025 14.3 0.2 0.053 13.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) DUF4279 PF14106.6 OWF51736.1 - 0.056 13.6 8.3 1.2 9.4 0.3 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4279) LURAP PF14854.6 OWF51737.1 - 1.1e-05 25.3 2.8 1.1e-05 25.3 2.8 2.1 1 1 1 2 2 2 1 Leucine rich adaptor protein HTH_WhiA PF02650.14 OWF51737.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.2 2 1 0 2 2 2 0 WhiA C-terminal HTH domain ISK_Channel PF02060.15 OWF51738.1 - 0.0093 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Slow voltage-gated potassium channel BTB PF00651.31 OWF51739.1 - 1.9e-20 73.2 0.4 5.2e-20 71.7 0.3 1.8 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF51739.1 - 0.024 14.7 0.1 0.61 10.2 0.1 2.7 1 1 0 1 1 1 0 BTB And C-terminal Kelch Jacalin PF01419.17 OWF51739.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Jacalin-like lectin domain DUF3342 PF11822.8 OWF51739.1 - 1.2 9.3 3.8 2.7 8.2 0.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) T4_deiodinase PF00837.17 OWF51740.1 - 7.8e-34 117.0 0.0 8.8e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase T4_deiodinase PF00837.17 OWF51741.1 - 3.9e-33 114.7 0.0 4.4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase T4_deiodinase PF00837.17 OWF51742.1 - 8.3e-32 110.4 0.0 9.3e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase TMEM154 PF15102.6 OWF51743.1 - 0.025 14.5 0.3 0.035 14.0 0.3 1.4 1 1 0 1 1 1 0 TMEM154 protein family COX2_TM PF02790.15 OWF51743.1 - 0.075 13.2 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1270 PF06900.11 OWF51743.1 - 0.088 13.2 0.3 0.2 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) ISK_Channel PF02060.15 OWF51743.1 - 0.094 12.4 1.1 0.11 12.2 0.2 1.6 2 0 0 2 2 2 0 Slow voltage-gated potassium channel EphA2_TM PF14575.6 OWF51743.1 - 0.13 13.1 0.1 0.25 12.2 0.1 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_18 PF00704.28 OWF51744.1 - 5e-169 561.9 12.3 2.6e-89 300.0 3.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF51744.1 - 9.7e-10 38.5 96.2 0.0068 16.6 7.1 6.8 6 0 0 6 6 6 5 Chitin binding Peritrophin-A domain DUF4666 PF15697.5 OWF51744.1 - 0.0036 18.0 0.4 7 7.4 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4666) DUF4849 PF16141.5 OWF51744.1 - 0.17 11.1 0.0 20 4.3 0.0 2.2 2 0 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 TBCC_N PF16752.5 OWF51744.1 - 0.18 12.3 0.0 38 4.8 0.0 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Glyco_hydro_18 PF00704.28 OWF51745.1 - 1.3e-179 596.7 8.9 3.9e-92 309.3 1.4 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 WW PF00397.26 OWF51745.1 - 0.13 12.3 3.7 4.3 7.5 0.3 2.7 2 0 0 2 2 2 0 WW domain Snf7 PF03357.21 OWF51747.1 - 0.52 9.9 10.4 3.5 7.2 2.0 3.4 1 1 1 2 2 2 0 Snf7 Laminin_EGF PF00053.24 OWF51748.1 - 3.7e-07 30.2 142.5 1.4 9.1 13.5 9.1 1 1 8 9 9 9 7 Laminin EGF domain SKG6 PF08693.10 OWF51748.1 - 0.33 10.4 2.6 0.53 9.7 2.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Y_phosphatase PF00102.27 OWF51749.1 - 2.2e-80 269.6 4.9 2e-45 155.2 2.9 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF51749.1 - 1.2e-08 35.3 0.1 2e-05 24.7 0.0 2.5 2 1 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 OWF51749.1 - 2.9e-06 27.1 1.6 0.00017 21.4 0.0 3.2 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF51749.1 - 0.00018 21.7 0.6 0.0086 16.2 0.0 3.1 3 1 0 3 3 3 1 Inositol hexakisphosphate RibD_C PF01872.17 OWF51749.1 - 0.03 14.1 0.0 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 RibD C-terminal domain Y_phosphatase2 PF03162.13 OWF51749.1 - 0.045 13.3 2.5 0.43 10.1 0.1 2.9 3 1 0 3 3 3 0 Tyrosine phosphatase family DSL PF01414.19 OWF51750.1 - 0.015 15.6 15.8 0.015 15.6 15.8 9.7 7 1 2 9 9 9 0 Delta serrate ligand EphA2_TM PF14575.6 OWF51750.1 - 0.14 13.1 0.0 0.38 11.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain 7tm_1 PF00001.21 OWF51751.1 - 2.5e-72 243.4 8.1 3.7e-72 242.8 8.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF51751.1 - 1.6e-08 34.2 14.4 3.2e-06 26.7 7.2 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF51751.1 - 6e-05 22.8 10.5 6e-05 22.8 10.5 2.1 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF51751.1 - 0.00087 19.1 10.0 0.0018 18.0 6.1 2.2 2 0 0 2 2 2 1 Olfactory receptor FERM_f0 PF16511.5 OWF51752.1 - 0.00015 22.0 22.5 2 8.8 0.6 7.0 2 2 4 6 6 6 5 N-terminal or F0 domain of Talin-head FERM AGS_C PF18134.1 OWF51752.1 - 0.0021 18.1 5.8 33 4.5 0.0 5.2 1 1 3 4 4 4 4 Adenylyl/Guanylyl and SMODS C-terminal sensor domain FtsK_SpoIIIE_N PF12538.8 OWF51752.1 - 3.9 7.7 25.7 27 5.0 0.3 6.3 1 1 5 7 7 7 0 DNA transporter DUF3933 PF13069.6 OWF51753.1 - 9.1e-06 25.4 9.3 4.6 7.2 0.1 6.0 1 1 5 6 6 6 4 Protein of unknown function (DUF3933) DUF3603 PF12227.8 OWF51753.1 - 0.0013 18.1 11.8 0.37 10.1 0.9 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3603) DUF3922 PF13059.6 OWF51753.1 - 0.11 13.0 22.8 2.8 8.4 5.2 4.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3992) EST1 PF10374.9 OWF51753.1 - 0.63 10.7 7.8 12 6.6 7.8 2.2 1 1 0 1 1 1 0 Telomerase activating protein Est1 HlyD PF00529.20 OWF51753.1 - 0.73 9.8 7.1 21 5.1 1.1 4.2 2 2 1 3 3 3 0 HlyD membrane-fusion protein of T1SS Imm59 PF15597.6 OWF51753.1 - 5.5 7.5 9.4 4.3 7.9 0.4 3.2 1 1 2 3 3 3 0 Immunity protein 59 DHHC PF01529.20 OWF51755.1 - 3e-32 111.5 12.0 3e-32 111.5 12.0 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 OWF51755.1 - 0.027 14.3 3.2 0.052 13.4 3.2 1.4 1 0 0 1 1 1 0 Ribosomal L40e family DUF4744 PF15918.5 OWF51756.1 - 0.0065 17.3 46.7 3.1 8.7 3.9 6.5 2 2 4 6 6 6 6 Domain of unknown function (DUF4744) zf-B_box PF00643.24 OWF51758.1 - 1.3e-11 44.5 22.5 2.5e-09 37.1 7.9 3.9 3 1 0 3 3 2 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF51758.1 - 2.1e-08 33.9 11.4 2.1e-08 33.9 11.4 3.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF51758.1 - 2.4e-08 33.8 8.8 2.4e-08 33.8 8.8 3.1 3 1 0 3 3 2 1 RING-type zinc-finger NHL PF01436.21 OWF51758.1 - 2.7e-08 33.5 1.0 0.0041 17.1 0.1 3.8 3 0 0 3 3 3 2 NHL repeat SGL PF08450.12 OWF51758.1 - 1.1e-06 28.5 3.9 0.14 11.7 0.1 4.4 1 1 4 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4_2 PF13923.6 OWF51758.1 - 3.5e-06 26.8 11.2 3.5e-06 26.8 11.2 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF51758.1 - 4e-06 26.6 9.3 4e-06 26.6 9.3 4.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51758.1 - 1.1e-05 25.5 12.2 1.1e-05 25.5 12.2 4.2 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF51758.1 - 1.3e-05 25.4 10.6 1.3e-05 25.4 10.6 3.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OWF51758.1 - 5.2e-05 23.1 11.4 5.2e-05 23.1 11.4 3.6 3 1 0 3 3 2 1 zinc-RING finger domain SBBP PF06739.11 OWF51758.1 - 0.0002 21.3 0.1 0.0059 16.6 0.0 2.6 2 0 0 2 2 2 1 Beta-propeller repeat Prok-RING_4 PF14447.6 OWF51758.1 - 0.00036 20.3 8.3 0.00036 20.3 8.3 3.7 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 C1_4 PF07975.12 OWF51758.1 - 0.001 19.2 2.1 0.001 19.2 2.1 4.7 3 1 0 3 3 2 1 TFIIH C1-like domain Reg_prop PF07494.11 OWF51758.1 - 0.0016 18.4 1.4 5 7.7 0.1 4.4 5 0 0 5 5 3 1 Two component regulator propeller zf-MIZ PF02891.20 OWF51758.1 - 8.8 6.2 19.3 0.046 13.5 8.6 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger NDK PF00334.19 OWF51759.1 - 0.08 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Nucleoside diphosphate kinase TFIIA_gamma_C PF02751.14 OWF51760.1 - 0.068 13.3 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit Ni_hydr_CYTB PF01292.20 OWF51760.1 - 0.071 12.7 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SEA PF01390.20 OWF51761.1 - 9e-12 45.0 0.1 9e-12 45.0 0.1 6.4 1 1 4 7 7 7 1 SEA domain SEA PF01390.20 OWF51762.1 - 4.3e-25 87.9 4.4 6.9e-15 55.0 0.2 3.1 2 0 0 2 2 2 2 SEA domain WAP PF00095.21 OWF51762.1 - 3.5e-11 43.3 16.7 3.7e-10 40.0 16.7 3.0 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' HNH_3 PF13392.6 OWF51763.1 - 0.045 13.5 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 HNH endonuclease HTH_psq PF05225.16 OWF51764.1 - 8.1e-27 92.7 0.1 6.3e-13 48.2 0.1 2.4 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_23 PF13384.6 OWF51764.1 - 0.13 12.0 0.2 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain PAAR_motif PF05488.13 OWF51765.1 - 8.7e-05 22.6 0.0 3 8.1 0.0 3.6 1 1 3 4 4 4 3 PAAR motif Cep57_CLD_2 PF14197.6 OWF51765.1 - 0.0036 17.4 35.2 0.098 12.8 8.3 4.9 1 1 2 3 3 3 1 Centrosome localisation domain of PPC89 ZapB PF06005.12 OWF51765.1 - 0.0048 17.3 50.5 6.4 7.3 6.8 5.6 1 1 3 4 4 4 2 Cell division protein ZapB FtsL PF04999.13 OWF51765.1 - 0.008 16.2 32.1 0.55 10.3 2.9 5.1 1 1 4 5 5 5 3 Cell division protein FtsL CENP-H PF05837.12 OWF51765.1 - 0.013 15.9 35.3 0.026 14.9 5.4 3.4 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Rootletin PF15035.6 OWF51765.1 - 0.45 10.5 43.9 2 8.4 6.1 3.4 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 OWF51765.1 - 1.2 9.6 42.2 1.3 9.5 19.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 OWF51765.1 - 9.6 6.9 38.3 69 4.2 10.2 4.9 1 1 2 3 3 3 0 Initiation control protein YabA MORN PF02493.20 OWF51766.1 - 5.4e-21 73.2 21.7 1.4e-05 24.7 2.1 5.8 6 0 0 6 6 6 4 MORN repeat Rib PF08428.10 OWF51766.1 - 0.13 12.3 0.7 9.8 6.2 0.0 2.9 2 1 0 2 2 2 0 Rib/alpha-like repeat DEAD PF00270.29 OWF51767.1 - 1.3e-15 57.6 0.2 2.1e-14 53.7 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF51767.1 - 4.8e-11 43.0 0.0 8.5e-10 39.0 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_79n PF03662.14 OWF51768.1 - 4.7e-31 107.9 0.5 1e-29 103.5 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain LRR_8 PF13855.6 OWF51769.1 - 2e-12 46.6 9.5 2.1e-09 37.0 1.5 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF51769.1 - 6.8e-09 35.9 11.9 2.8e-05 24.4 1.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) AAA_23 PF13476.6 OWF51769.1 - 0.068 13.7 11.3 0.13 12.7 1.1 2.3 2 0 0 2 2 2 0 AAA domain LRR_1 PF00560.33 OWF51769.1 - 0.094 13.3 16.8 0.29 11.8 0.1 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat DUF1064 PF06356.11 OWF51770.1 - 0.013 15.9 15.7 0.62 10.4 0.2 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1064) Ig_3 PF13927.6 OWF51772.1 - 2.2e-23 82.6 0.0 6.8e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF51772.1 - 1.2e-21 76.6 0.0 1.5e-09 37.8 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF51772.1 - 3.2e-16 59.4 0.0 3.3e-07 30.5 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 OWF51772.1 - 2e-15 56.7 0.0 1.2e-07 31.8 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF51772.1 - 1.1e-07 32.0 0.0 0.0044 17.2 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF51772.1 - 1.1e-06 28.6 0.1 0.0077 16.3 0.0 2.8 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF51772.1 - 0.0034 17.7 0.0 6 7.4 0.0 3.7 2 2 2 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 OWF51772.1 - 0.079 13.3 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Xan_ur_permease PF00860.20 OWF51773.1 - 2.4e-59 201.0 20.9 3e-59 200.7 20.9 1.1 1 0 0 1 1 1 1 Permease family DoxD PF04173.13 OWF51773.1 - 0.0042 17.0 0.6 0.012 15.5 0.6 1.7 1 0 0 1 1 1 1 TQO small subunit DoxD Xan_ur_permease PF00860.20 OWF51774.1 - 1.7e-68 231.1 28.9 6.7e-68 229.2 28.9 1.8 1 1 0 1 1 1 1 Permease family CARD_2 PF16739.5 OWF51775.1 - 2.3e-15 56.3 0.6 2.3e-15 56.3 0.6 1.9 2 0 0 2 2 2 1 Caspase recruitment domain Death PF00531.22 OWF51775.1 - 8.6e-10 38.7 7.6 2.6e-09 37.1 1.4 2.4 2 0 0 2 2 2 2 Death domain Tetraspanin PF00335.20 OWF51776.1 - 2.4e-48 164.8 6.4 2.8e-48 164.6 6.4 1.0 1 0 0 1 1 1 1 Tetraspanin family Herpes_LMP1 PF05297.11 OWF51776.1 - 5.7 6.0 9.2 20 4.3 7.2 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Glyco_transf_10 PF00852.19 OWF51779.1 - 2.8e-46 157.4 3.1 4.2e-46 156.9 3.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF51779.1 - 5e-16 59.1 1.0 5.5e-15 55.8 0.1 2.4 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal RNA_pol_Rpc4 PF05132.14 OWF51780.1 - 4.7e-28 98.5 2.7 2.7e-27 96.0 0.4 2.9 2 1 0 2 2 2 1 RNA polymerase III RPC4 CH PF00307.31 OWF51781.1 - 5.7e-13 49.0 0.3 4.9e-05 23.5 0.1 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain FPP PF05911.11 OWF51781.1 - 0.001 17.4 4.7 0.001 17.4 4.7 2.3 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 OWF51781.1 - 0.0044 17.4 4.1 0.0044 17.4 4.1 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4200) YkyA PF10368.9 OWF51781.1 - 0.93 9.1 12.8 0.76 9.4 1.1 3.0 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein CENP-F_leu_zip PF10473.9 OWF51781.1 - 6.6 6.8 35.6 0.025 14.6 10.1 4.3 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 OWF51781.1 - 8 5.6 8.2 1.5 8.0 1.7 2.2 2 0 0 2 2 2 0 TMPIT-like protein zf-B_box PF00643.24 OWF51782.1 - 6.7e-08 32.6 4.5 2.2e-07 30.9 4.5 1.9 1 0 0 1 1 1 1 B-box zinc finger NHL PF01436.21 OWF51782.1 - 6e-05 22.9 0.5 0.053 13.6 0.1 3.3 2 0 0 2 2 2 2 NHL repeat SGL PF08450.12 OWF51782.1 - 0.0002 21.1 0.0 1.4 8.5 0.0 3.1 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF51782.1 - 0.016 15.3 0.1 12 6.5 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller OrsD PF12013.8 OWF51782.1 - 0.078 13.4 2.1 0.43 11.1 1.0 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D PI3K_P85_iSH2 PF16454.5 OWF51782.1 - 0.16 11.6 6.5 0.17 11.4 4.3 1.9 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Siva PF05458.12 OWF51782.1 - 0.17 11.5 3.1 1.4 8.6 1.6 2.4 2 0 0 2 2 2 0 Cd27 binding protein (Siva) GrpE PF01025.19 OWF51782.1 - 0.56 9.8 3.2 0.85 9.3 1.9 1.9 2 0 0 2 2 2 0 GrpE Sec7 PF01369.20 OWF51783.1 - 5.5e-63 212.0 1.5 8.7e-63 211.3 1.5 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OWF51783.1 - 1.2e-27 96.8 5.5 1.2e-27 96.8 5.5 4.6 4 1 1 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1045 PF06299.12 OWF51783.1 - 0.069 13.1 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) UME PF08064.13 OWF51783.1 - 0.21 11.5 1.0 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 UME (NUC010) domain Homeodomain PF00046.29 OWF51784.1 - 1.7e-22 79.0 8.5 2.9e-22 78.3 8.5 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 OWF51784.1 - 6.6e-08 32.1 0.9 2.1e-07 30.5 0.8 1.9 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.11 OWF51784.1 - 0.0019 18.1 0.6 0.0019 18.1 0.6 2.6 3 0 0 3 3 3 1 Homeobox KN domain GAIN_A PF18619.1 OWF51784.1 - 0.31 11.3 2.0 0.74 10.1 2.0 1.6 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A QLQ PF08880.11 OWF51784.1 - 3.4 7.5 5.2 0.69 9.7 1.2 1.9 2 0 0 2 2 2 0 QLQ ERAP1_C PF11838.8 OWF51785.1 - 5.3e-82 275.9 0.2 7.8e-82 275.3 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OWF51785.1 - 1.5e-81 273.1 1.2 2.8e-81 272.3 1.2 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OWF51785.1 - 4.7e-43 147.5 0.3 9.4e-43 146.6 0.1 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain TM2 PF05154.16 OWF51786.1 - 2e-41 140.1 63.3 3.2e-13 49.8 6.1 4.2 4 0 0 4 4 4 4 TM2 domain DUF2076 PF09849.9 OWF51786.1 - 8.9 6.3 19.2 16 5.4 19.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) 7tm_1 PF00001.21 OWF51788.1 - 3.6e-34 118.3 16.1 6.6e-34 117.4 16.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF51788.1 - 5.2e-05 23.0 25.0 0.00045 19.9 21.6 2.6 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.13 OWF51788.1 - 0.0051 16.0 18.3 0.012 14.7 18.3 1.6 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) Annexin PF00191.20 OWF51789.1 - 1.7e-95 313.1 12.9 9.6e-25 86.4 0.6 4.2 4 0 0 4 4 4 4 Annexin IMUP PF15761.5 OWF51789.1 - 0.0078 16.9 10.6 0.0078 16.9 10.6 1.9 2 0 0 2 2 2 1 Immortalisation up-regulated protein SR-25 PF10500.9 OWF51789.1 - 0.022 14.4 13.4 0.037 13.7 13.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myb_DNA-bind_7 PF15963.5 OWF51789.1 - 0.036 14.0 0.5 3.4 7.6 0.1 3.2 3 0 0 3 3 3 0 Myb DNA-binding like DUF508 PF04370.12 OWF51789.1 - 0.13 12.0 2.0 0.22 11.2 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF4605 PF15378.6 OWF51790.1 - 5e-21 74.3 2.7 8.3e-21 73.6 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) zf_C2HC_14 PF18574.1 OWF51791.1 - 4.9e-06 26.2 0.1 19 5.1 0.0 7.1 6 2 2 8 8 8 1 C2HC Zing finger domain Peptidase_C21 PF05381.12 OWF51791.1 - 2e-05 24.9 14.1 1.1 9.6 0.3 5.5 1 1 4 5 5 5 5 Tymovirus endopeptidase VKG_Carbox PF05090.14 OWF51791.1 - 1 8.2 6.0 2.5 6.8 0.3 2.1 1 1 0 2 2 2 0 Vitamin K-dependent gamma-carboxylase HlyIII PF03006.20 OWF51792.1 - 1.3e-25 90.5 16.9 1.3e-25 90.5 16.9 2.3 2 0 0 2 2 2 1 Haemolysin-III related Cas_Csn2 PF09711.10 OWF51792.1 - 0.096 12.3 0.7 0.16 11.6 0.7 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) HlyIII PF03006.20 OWF51793.1 - 1.2e-28 100.3 16.2 1.2e-28 100.3 16.2 1.6 2 0 0 2 2 2 1 Haemolysin-III related HlyIII PF03006.20 OWF51794.1 - 7e-27 94.6 22.9 7e-27 94.6 22.9 1.4 2 0 0 2 2 2 1 Haemolysin-III related PDCD2_C PF04194.13 OWF51795.1 - 3.1e-35 121.8 0.6 3.3e-34 118.5 0.0 2.5 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain SIN1 PF05422.12 OWF51795.1 - 1.1 9.9 4.4 0.47 11.0 0.6 2.3 3 0 0 3 3 3 0 Stress-activated map kinase interacting protein 1 (SIN1) WD40 PF00400.32 OWF51796.1 - 2.7e-24 85.0 0.7 3.6e-05 24.4 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF51796.1 - 4.6e-06 26.8 0.1 0.052 13.9 0.0 4.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF51796.1 - 0.003 16.6 0.1 1.5 7.7 0.0 3.2 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OWF51796.1 - 0.0044 15.8 0.1 0.67 8.6 0.0 3.0 1 1 3 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 OWF51796.1 - 0.026 13.9 0.0 0.29 10.4 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain HPS3_N PF14761.6 OWF51796.1 - 0.041 13.4 0.0 0.097 12.2 0.0 1.6 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 DUF2415 PF10313.9 OWF51796.1 - 0.06 13.3 0.0 0.51 10.3 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Frtz PF11768.8 OWF51796.1 - 0.08 11.2 0.0 0.28 9.5 0.0 1.7 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2367 PF10164.9 OWF51797.1 - 4.3e-36 123.6 9.5 4.3e-36 123.6 9.5 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2367) zf-ribbon_3 PF13248.6 OWF51797.1 - 0.028 13.8 1.3 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 OWF51798.1 - 5e-76 255.6 0.0 5.7e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51798.1 - 3.6e-35 121.5 0.0 5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF51798.1 - 1.3e-05 24.3 0.1 4.6e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OWF51798.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OWF51798.1 - 0.0061 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OWF51798.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OWF51798.1 - 0.087 12.2 0.1 0.32 10.3 0.1 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Raptor_N PF14538.6 OWF51799.1 - 3.7e-72 241.1 0.0 7.5e-72 240.1 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OWF51799.1 - 4.6e-13 49.4 10.3 0.021 15.7 0.0 7.6 8 0 0 8 8 8 3 WD domain, G-beta repeat HEAT PF02985.22 OWF51799.1 - 5.7e-08 32.4 2.1 0.00095 19.2 0.0 4.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 OWF51799.1 - 2.4e-05 24.6 0.3 0.00029 21.2 0.0 2.8 2 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 OWF51799.1 - 5e-05 23.7 0.3 0.0029 18.1 0.0 3.1 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 OWF51799.1 - 8.8e-05 22.6 0.0 0.002 18.2 0.0 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 OWF51799.1 - 0.0023 18.2 0.0 7.6 6.9 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SUFU PF05076.13 OWF51800.1 - 1.6e-41 142.2 0.0 2.7e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) SUFU_C PF12470.8 OWF51800.1 - 1.4e-26 93.8 0.1 2.3e-19 70.3 0.0 2.1 1 1 1 2 2 2 2 Suppressor of Fused Gli/Ci N terminal binding domain PKD_channel PF08016.12 OWF51801.1 - 1.7e-84 284.0 19.7 1.7e-84 284.0 19.7 2.1 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.15 OWF51801.1 - 1e-43 149.8 2.0 2.2e-36 125.7 0.8 2.7 2 0 0 2 2 2 2 REJ domain PLAT PF01477.23 OWF51801.1 - 7.2e-13 49.1 0.0 2.7e-12 47.3 0.0 2.0 1 0 0 1 1 1 1 PLAT/LH2 domain TSP_1 PF00090.19 OWF51801.1 - 3.4e-08 33.6 34.2 1.1e-06 28.7 6.3 3.8 3 1 0 3 3 3 2 Thrombospondin type 1 domain GPS PF01825.21 OWF51801.1 - 0.012 16.1 2.0 0.012 16.1 2.0 3.4 3 0 0 3 3 3 0 GPCR proteolysis site, GPS, motif Toxin_ToxA PF11584.8 OWF51801.1 - 0.062 13.3 0.3 2.1 8.4 0.0 3.1 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA CBM_6 PF03422.15 OWF51801.1 - 0.58 10.5 4.3 1.6 9.0 0.0 3.2 3 0 0 3 3 3 0 Carbohydrate binding module (family 6) PALP PF00291.25 OWF51802.1 - 3.4e-66 223.6 0.1 4e-66 223.4 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LpxI_N PF17930.1 OWF51802.1 - 1.2 9.0 3.6 32 4.4 0.1 3.6 3 1 1 4 4 4 0 LpxI N-terminal domain PALP PF00291.25 OWF51803.1 - 2.5e-64 217.5 0.1 2.9e-64 217.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NPL4 PF05021.15 OWF51804.1 - 2.4e-114 381.8 0.0 3.2e-114 381.4 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 OWF51804.1 - 9.5e-59 197.7 0.3 1.7e-58 196.9 0.3 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OWF51804.1 - 6.3e-20 71.4 0.0 2.3e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 ADD_DNMT3 PF17980.1 OWF51804.1 - 0.013 15.5 0.8 0.032 14.2 0.8 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 MarR_2 PF12802.7 OWF51805.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 MarR family DUF3715 PF12509.8 OWF51806.1 - 2.7e-21 76.1 0.0 2.7e-21 76.1 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3715) Vps35 PF03635.17 OWF51807.1 - 1.1e-05 24.2 22.8 0.0015 17.1 7.2 3.8 2 2 2 4 4 4 3 Vacuolar protein sorting-associated protein 35 DUF4441 PF14536.6 OWF51807.1 - 0.073 13.3 3.0 8.8 6.6 0.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) TPR_2 PF07719.17 OWF51807.1 - 0.08 13.1 0.4 39 4.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Med9 PF07544.13 OWF51808.1 - 6.1e-20 71.1 3.0 7.1e-20 70.9 3.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 OWF51808.1 - 0.0016 18.7 2.1 0.006 16.8 2.2 1.7 1 1 1 2 2 2 1 Subunit 21 of Mediator complex RPW8 PF05659.11 OWF51808.1 - 0.0019 17.9 2.0 0.0057 16.4 2.0 1.7 1 1 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_p24 PF05073.12 OWF51808.1 - 0.008 16.0 2.0 0.0085 15.9 2.0 1.1 1 0 0 1 1 1 1 Baculovirus P24 capsid protein BLOC1_2 PF10046.9 OWF51808.1 - 0.018 15.4 1.4 0.022 15.0 1.1 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.6 OWF51808.1 - 0.023 14.2 0.4 0.023 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CC2-LZ PF16516.5 OWF51808.1 - 0.032 14.6 3.3 0.045 14.1 3.3 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1460 PF07313.12 OWF51808.1 - 0.053 12.9 0.4 0.06 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Rho_Binding PF08912.11 OWF51808.1 - 0.081 13.8 3.8 0.18 12.6 3.1 1.8 1 1 1 2 2 2 0 Rho Binding Gemin6 PF06372.12 OWF51809.1 - 3.2e-43 147.2 0.1 3.9e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 Gemin6 protein AD PF09793.9 OWF51809.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.6 1 1 0 1 1 1 0 Anticodon-binding domain POTRA PF07244.15 OWF51809.1 - 0.085 13.4 0.2 0.15 12.7 0.2 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat SNF2_N PF00176.23 OWF51810.1 - 4.1e-53 180.3 0.0 9.3e-53 179.2 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF51810.1 - 1.1e-17 64.4 0.0 3e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF51810.1 - 3.8e-09 36.8 0.0 4.6e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OWF51810.1 - 0.0014 17.8 0.0 0.0042 16.3 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 OWF51810.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2439 PF10382.9 OWF51810.1 - 0.11 12.9 0.8 0.44 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) zf-RING_UBOX PF13445.6 OWF51811.1 - 2.4e-07 30.6 3.9 2.4e-07 30.6 3.9 2.5 2 1 0 2 2 1 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 OWF51811.1 - 5.7e-07 29.9 7.4 5.7e-07 29.9 7.4 2.9 1 1 2 3 3 3 1 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 OWF51811.1 - 5.7e-07 29.3 7.5 5.7e-07 29.3 7.5 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 OWF51811.1 - 6.4e-07 30.0 7.2 6.4e-07 30.0 7.2 4.3 2 1 2 4 4 4 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 OWF51811.1 - 1.8e-06 27.7 8.9 1.8e-06 27.7 8.9 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF51811.1 - 2.1e-06 27.5 9.3 2.1e-06 27.5 9.3 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51811.1 - 1.1e-05 25.4 7.0 1.1e-05 25.4 7.0 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF51811.1 - 7.9e-05 22.5 8.4 7.9e-05 22.5 8.4 3.8 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF51811.1 - 0.00046 20.5 8.4 0.00046 20.5 8.4 3.7 3 1 1 4 4 3 1 Ring finger domain Prok-RING_4 PF14447.6 OWF51811.1 - 0.00046 20.0 7.9 0.00046 20.0 7.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OWF51811.1 - 0.0011 18.8 2.7 0.0011 18.8 2.7 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 OWF51811.1 - 0.0017 18.1 4.1 0.0017 18.1 4.1 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.16 OWF51811.1 - 0.003 17.5 10.6 0.0035 17.3 8.6 2.1 1 1 0 2 2 2 1 Seven in absentia protein family U-box PF04564.15 OWF51811.1 - 0.024 14.8 0.1 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 U-box domain Rad50_zn_hook PF04423.14 OWF51811.1 - 0.035 14.0 4.0 0.12 12.2 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Mlf1IP PF10248.9 OWF51811.1 - 0.24 11.4 2.6 0.46 10.4 2.6 1.4 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein NUDIX PF00293.28 OWF51812.1 - 8.7e-13 48.4 0.2 1.5e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain ECH_1 PF00378.20 OWF51813.1 - 1e-62 211.7 0.0 1.2e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF51813.1 - 2e-15 57.2 0.0 2.5e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OWF51813.1 - 0.012 15.6 0.2 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 M_domain PF12938.7 OWF51814.1 - 1.3e-06 28.4 65.1 1.3e-06 28.4 65.1 8.3 5 3 3 8 8 8 1 M domain of GW182 UBA PF00627.31 OWF51814.1 - 6e-06 26.1 0.3 1.3e-05 25.0 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.22 OWF51814.1 - 2e-05 24.3 0.0 4.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C4 PF00105.18 OWF51816.1 - 2.6e-27 95.1 9.8 5.4e-27 94.0 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF51816.1 - 4.3e-16 59.1 0.1 1.7e-15 57.2 0.1 2.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF2362 PF10154.9 OWF51817.1 - 6.5e-203 675.2 16.4 7.5e-203 675.0 16.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Sulfotransfer_3 PF13469.6 OWF51817.1 - 0.26 11.6 2.3 1.3 9.4 2.3 2.1 1 1 0 1 1 1 0 Sulfotransferase family TPR_21 PF09976.9 OWF51817.1 - 0.56 9.9 5.2 0.066 12.9 0.6 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Thioredoxin PF00085.20 OWF51818.1 - 4.4e-62 206.5 0.3 3.8e-31 107.1 0.0 3.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 OWF51818.1 - 1.4e-45 155.5 0.2 1.9e-37 129.0 0.3 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OWF51818.1 - 1.4e-11 44.8 1.2 4e-05 24.0 0.0 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OWF51818.1 - 3.4e-10 40.0 0.1 0.00095 19.3 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 OWF51818.1 - 2.5e-09 36.9 0.0 0.00054 19.4 0.0 3.1 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OWF51818.1 - 2.8e-07 30.8 0.4 0.0048 17.2 0.1 4.0 3 1 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.17 OWF51818.1 - 4.2e-07 29.3 1.6 5.8e-07 28.9 0.6 1.8 2 0 0 2 2 2 1 Calsequestrin ERp29_N PF07912.13 OWF51818.1 - 5.3e-07 29.8 1.0 0.36 11.0 0.0 4.4 4 0 0 4 4 4 1 ERp29, N-terminal domain AhpC-TSA PF00578.21 OWF51818.1 - 6.8e-07 29.3 0.8 0.031 14.2 0.1 3.6 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 OWF51818.1 - 6.1e-06 26.0 0.7 0.065 12.9 0.1 3.5 3 0 0 3 3 3 1 Redoxin Thioredoxin_9 PF14595.6 OWF51818.1 - 0.0044 16.8 0.0 0.57 10.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 OWF51818.1 - 0.014 15.4 0.0 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE NOA36 PF06524.12 OWF51818.1 - 0.018 14.4 5.3 0.028 13.8 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein SGT1 PF07093.11 OWF51818.1 - 0.024 13.1 3.6 0.039 12.4 3.6 1.2 1 0 0 1 1 1 0 SGT1 protein Glutaredoxin PF00462.24 OWF51818.1 - 0.045 14.0 0.1 2.8 8.2 0.0 2.9 2 0 0 2 2 2 0 Glutaredoxin DUF4170 PF13773.6 OWF51818.1 - 0.11 12.6 0.7 0.29 11.3 0.2 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4170) TraF PF13728.6 OWF51818.1 - 0.2 11.5 0.0 4 7.2 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein RXT2_N PF08595.11 OWF51818.1 - 0.73 9.9 3.9 1.3 9.0 3.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal KIND PF16474.5 OWF51818.1 - 1.5 8.6 5.3 3.3 7.6 5.3 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain DNA_pol_phi PF04931.13 OWF51818.1 - 3.3 5.7 11.2 4.7 5.2 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 OWF51818.1 - 3.6 8.0 14.4 13 6.3 14.4 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ECH_1 PF00378.20 OWF51819.1 - 2e-88 295.9 0.5 2.3e-88 295.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF51819.1 - 3.1e-35 122.3 0.8 2.7e-30 106.0 0.2 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OWF51819.1 - 0.0094 15.9 0.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase family S49 APOBEC_C PF05240.14 OWF51819.1 - 0.17 11.9 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Acyl_transf_1 PF00698.21 OWF51822.1 - 1.3e-83 281.2 0.0 3.1e-83 279.9 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 OWF51822.1 - 4.8e-55 186.9 0.0 8.4e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 OWF51822.1 - 2.1e-47 161.4 0.1 5.7e-47 159.9 0.0 1.9 2 0 0 2 2 1 1 KR domain Ketoacyl-synt_C PF02801.22 OWF51822.1 - 8.7e-25 87.0 0.0 2e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 OWF51822.1 - 3.9e-17 62.4 0.0 8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 OWF51822.1 - 1.2e-16 61.2 0.1 3.2e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 OWF51822.1 - 1.9e-15 57.7 0.0 4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 OWF51822.1 - 5.2e-08 33.1 0.3 2.2e-07 31.1 0.3 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 OWF51822.1 - 2.6e-05 24.1 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OWF51822.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_6 PF12697.7 OWF51822.1 - 0.00017 22.2 0.0 0.026 15.1 0.0 3.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.6 OWF51822.1 - 0.0002 21.2 0.0 0.00092 19.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 OWF51822.1 - 0.00043 21.3 0.0 0.01 16.9 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OWF51822.1 - 0.013 15.5 0.0 0.19 11.7 0.0 2.9 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 OWF51822.1 - 0.075 13.8 0.0 0.31 11.8 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 OWF51822.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pentapeptide_2 PF01469.18 OWF51822.1 - 0.27 11.2 2.5 0.58 10.1 2.5 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Arfaptin PF06456.13 OWF51823.1 - 1.5e-78 263.5 5.6 1.5e-78 263.5 5.6 1.4 2 0 0 2 2 2 1 Arfaptin-like domain PDZ PF00595.24 OWF51823.1 - 7.3e-10 39.1 0.1 1.5e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain BAR PF03114.18 OWF51823.1 - 1.8e-06 27.8 6.1 6.5e-06 26.0 5.4 2.2 1 1 1 2 2 2 1 BAR domain PDZ_6 PF17820.1 OWF51823.1 - 3.7e-06 26.7 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF51823.1 - 1.3e-05 25.4 0.0 3.9e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain BAR_3 PF16746.5 OWF51823.1 - 6.6e-05 22.7 5.4 0.0026 17.5 5.4 2.3 1 1 0 1 1 1 1 BAR domain of APPL family GIDA_assoc PF13932.6 OWF51823.1 - 9.3 6.4 8.0 2.5 8.2 1.0 2.8 1 1 2 3 3 3 0 GidA associated domain SPRY PF00622.28 OWF51824.1 - 2.5e-17 63.1 0.0 3.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 OWF51824.1 - 0.00012 22.4 0.0 0.0002 21.7 0.0 1.3 1 0 0 1 1 1 1 SOCS box DUF5557 PF17712.1 OWF51824.1 - 0.055 13.4 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5557) BTB PF00651.31 OWF51825.1 - 5.3e-24 84.6 0.4 4.9e-23 81.5 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF51825.1 - 5.8e-06 26.3 0.2 1.8e-05 24.8 0.2 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch TetR_N PF00440.23 OWF51825.1 - 0.0072 16.1 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family c-SKI_SMAD_bind PF08782.10 OWF51826.1 - 0.00079 19.6 1.0 0.003 17.8 1.0 2.0 1 0 0 1 1 1 1 c-SKI Smad4 binding domain E1_dh PF00676.20 OWF51827.1 - 6.7e-80 268.2 0.1 1.1e-79 267.6 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 OWF51827.1 - 6.6e-62 208.3 0.0 1.2e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OWF51827.1 - 1.8e-54 183.5 0.0 3e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OWF51827.1 - 3.5e-17 61.7 1.4 9.7e-17 60.3 0.7 2.2 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus GGA_N-GAT PF18308.1 OWF51827.1 - 0.06 13.0 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 GGA N-GAT domain Beach PF02138.18 OWF51828.1 - 4.5e-124 413.3 1.0 7.6e-124 412.5 1.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 OWF51828.1 - 1.3e-17 63.7 11.5 1.3e-17 63.7 11.5 2.2 2 0 0 2 2 2 1 FYVE zinc finger PH_BEACH PF14844.6 OWF51828.1 - 7.5e-12 45.2 0.0 2.8e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 OWF51828.1 - 4.5e-09 35.9 0.4 4.3e-08 32.7 0.6 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) WD40 PF00400.32 OWF51828.1 - 1.2e-07 32.2 8.6 0.00068 20.4 0.1 6.0 5 1 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 OWF51828.1 - 0.0076 16.4 0.1 0.037 14.2 0.1 2.1 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily IBR PF01485.21 OWF51828.1 - 0.086 13.1 5.9 0.34 11.2 5.9 2.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 OWF51828.1 - 1.5 9.1 6.4 5.3 7.3 6.4 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 OWF51828.1 - 5 7.4 6.5 18 5.6 6.5 1.9 1 0 0 1 1 1 0 B-box zinc finger DLP_helical PF18709.1 OWF51829.1 - 0.063 12.5 0.0 0.43 9.7 0.0 2.3 1 1 0 1 1 1 0 Dynamin-like helical domain QCR10 PF09796.9 OWF51829.1 - 0.099 12.7 1.3 11 6.1 0.0 3.3 4 0 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF494 PF04361.13 OWF51830.1 - 0.051 13.5 0.2 25 4.7 0.1 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF494) Ly49 PF08391.10 OWF51830.1 - 0.29 11.5 1.8 0.71 10.3 1.8 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region TetR_C_19 PF17924.1 OWF51830.1 - 0.74 10.4 13.8 16 6.1 1.4 3.8 2 1 3 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Cornifin PF02389.15 OWF51830.1 - 1.2 9.4 26.9 6.7 6.9 9.6 4.5 3 2 0 3 3 3 0 Cornifin (SPRR) family MtlR PF05068.12 OWF51830.1 - 9.7 6.2 7.3 52 3.8 1.9 3.1 1 1 1 2 2 2 0 Mannitol repressor Antimicrobial_2 PF08023.12 OWF51831.1 - 0.03 14.9 0.8 36 5.0 0.0 3.7 1 1 2 3 3 3 0 Frog antimicrobial peptide MttA_Hcf106 PF02416.16 OWF51831.1 - 0.033 13.5 1.0 2.5 7.5 0.1 3.3 1 1 1 3 3 3 0 mttA/Hcf106 family Baculo_PEP_C PF04513.12 OWF51832.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short_C2 PF13561.6 OWF51833.1 - 7.1e-50 169.7 1.1 9.3e-50 169.4 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF51833.1 - 1.6e-39 135.4 0.8 2.1e-39 135.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF51833.1 - 3e-09 37.1 0.1 4.2e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OWF51834.1 - 2.4e-49 168.0 0.3 3.2e-49 167.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF51834.1 - 3.2e-41 140.9 0.2 4.1e-41 140.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF51834.1 - 7.9e-10 38.9 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Myosin_tail_1 PF01576.19 OWF51835.1 - 0 1239.1 314.8 0 1238.8 314.8 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 OWF51835.1 - 7.2e-302 1002.7 0.2 7.2e-302 1002.7 0.2 3.0 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.19 OWF51835.1 - 2.3e-12 46.5 0.1 6.8e-12 45.0 0.1 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 OWF51835.1 - 0.0023 18.0 9.2 0.0023 18.0 9.2 15.3 3 1 16 19 19 19 4 Protein of unknown function (DUF1664) IQ PF00612.27 OWF51835.1 - 0.016 15.0 2.5 0.021 14.6 0.3 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 OWF51835.1 - 0.034 14.4 0.0 0.034 14.4 0.0 6.3 5 1 1 6 6 6 0 AAA domain zf-HC5HC2H PF13771.6 OWF51836.1 - 1.8e-11 44.1 6.0 1.8e-11 44.1 6.0 3.4 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OWF51836.1 - 2.1e-08 34.3 5.7 2.1e-08 34.3 5.7 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain SAM_1 PF00536.30 OWF51836.1 - 5.5e-07 29.9 0.0 1.2e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF51836.1 - 7e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHD PF00628.29 OWF51836.1 - 6.3 6.8 19.2 1 9.3 8.7 4.0 4 0 0 4 4 4 0 PHD-finger MAD PF05557.13 OWF51837.1 - 1.9e-142 476.0 91.9 2.2e-142 475.7 91.9 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Peptidase_M14 PF00246.24 OWF51838.1 - 1.1e-72 245.2 0.1 1.5e-72 244.9 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 OWF51838.1 - 1.8e-07 31.3 0.1 3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OWF51838.1 - 0.06 13.3 0.2 0.27 11.3 0.2 2.0 1 1 0 1 1 1 0 CarboxypepD_reg-like domain DUF2817 PF10994.8 OWF51838.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 OWF51838.1 - 0.12 11.5 0.2 0.36 9.9 0.1 1.8 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family HMG_box PF00505.19 OWF51839.1 - 2e-22 79.4 7.8 4.8e-14 52.5 0.4 5.7 5 1 1 6 6 6 3 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF51839.1 - 1e-15 58.1 6.6 1.3e-08 35.3 0.0 4.9 5 2 1 6 6 6 3 HMG-box domain Peptidase_S49 PF01343.18 OWF51839.1 - 0.22 11.5 8.9 2.9 7.8 0.2 2.4 2 0 0 2 2 2 0 Peptidase family S49 CAML PF14963.6 OWF51840.1 - 1.5e-12 48.2 8.0 3.3e-12 47.1 8.0 1.5 1 1 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand Macoilin PF09726.9 OWF51840.1 - 2.6 6.5 7.9 3.2 6.2 7.9 1.0 1 0 0 1 1 1 0 Macoilin family Mito_carr PF00153.27 OWF51841.1 - 2.8e-63 209.9 0.9 4.1e-20 71.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF51841.1 - 0.093 11.9 2.0 5.5 6.1 0.0 3.3 4 0 0 4 4 4 0 Gammaproteobacterial serine protease CT47 PF15623.6 OWF51841.1 - 0.34 10.7 0.0 0.5 10.2 0.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 LPMO_10 PF03067.15 OWF51842.1 - 2.1e-38 132.9 1.4 2.9e-38 132.5 1.4 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading HLH PF00010.26 OWF51843.1 - 1e-14 54.2 0.2 2.7e-14 52.8 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MDM31_MDM32 PF08118.11 OWF51843.1 - 0.024 13.3 1.1 0.036 12.8 1.1 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Mucin-like PF16058.5 OWF51844.1 - 0.0026 17.8 0.0 0.011 15.8 0.0 1.4 1 1 0 1 1 1 1 Mucin-like VIT PF08487.10 OWF51845.1 - 7.8e-22 77.6 1.5 1.6e-21 76.6 0.6 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OWF51845.1 - 1.1e-18 68.0 1.1 2.2e-18 67.1 0.2 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF51845.1 - 7.7e-13 48.7 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF51845.1 - 1.8e-12 47.9 0.2 4.8e-12 46.5 0.2 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF51845.1 - 2.9e-06 26.9 0.1 5.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 OWF51845.1 - 9.3e-05 22.6 0.1 0.00028 21.1 0.1 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus CobT_C PF11775.8 OWF51845.1 - 0.047 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain DUF2201 PF09967.9 OWF51845.1 - 0.12 12.6 0.1 0.4 10.8 0.1 2.0 1 1 0 1 1 1 0 VWA-like domain (DUF2201) DUF2129 PF09902.9 OWF51845.1 - 0.12 12.5 0.3 0.43 10.7 0.3 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) NOG1 PF06858.14 OWF51845.1 - 0.12 12.2 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) VWA PF00092.28 OWF51846.1 - 1.9e-18 67.3 2.1 2.7e-18 66.8 0.4 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF51846.1 - 3.4e-18 66.1 0.0 6.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF51846.1 - 2e-12 47.7 0.1 8.3e-12 45.7 0.1 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OWF51846.1 - 5.7e-07 29.7 0.1 1.3e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 OWF51846.1 - 2.2e-06 27.2 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 OWF51846.1 - 2.5e-05 24.5 0.7 3.7e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 vWA found in TerF C terminus DUF2201 PF09967.9 OWF51846.1 - 0.0005 20.2 0.1 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 VWA-like domain (DUF2201) NOG1 PF06858.14 OWF51846.1 - 0.059 13.1 0.1 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) DUF2129 PF09902.9 OWF51846.1 - 0.12 12.5 0.3 0.37 10.9 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) PhzC-PhzF PF02567.16 OWF51847.1 - 5.3e-64 216.4 0.0 6.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein N_NLPC_P60 PF12912.7 OWF51847.1 - 0.027 14.9 0.1 0.24 11.8 0.0 2.3 2 1 1 3 3 3 0 NLPC_P60 stabilising domain, N term VPS28 PF03997.12 OWF51847.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 VPS28 protein DUF1487 PF07368.11 OWF51847.1 - 0.13 11.6 0.0 0.37 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) BRCC36_C PF18110.1 OWF51848.1 - 0.11 12.7 6.1 20 5.4 0.1 3.4 1 1 1 3 3 3 0 BRCC36 C-terminal helical domain POTRA_1 PF08478.10 OWF51849.1 - 0.00013 22.2 7.9 51 4.3 0.1 8.1 1 1 9 10 10 10 0 POTRA domain, FtsQ-type TFIIIC_sub6 PF10419.9 OWF51849.1 - 0.0017 18.2 0.7 13 5.7 0.1 4.6 1 1 4 5 5 5 1 TFIIIC subunit triple barrel domain DUF4430 PF14478.6 OWF51849.1 - 0.0017 18.9 22.3 3.6 8.3 0.2 7.7 1 1 6 7 7 7 1 Domain of unknown function (DUF4430) LRR_5 PF13306.6 OWF51849.1 - 0.013 15.5 5.2 0.26 11.3 1.6 2.1 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) DUF3319 PF11782.8 OWF51849.1 - 0.75 9.8 5.8 5.4 7.1 0.3 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF3319) Olfactory_mark PF06554.12 OWF51849.1 - 1.5 8.5 31.6 23 4.7 0.8 7.6 1 1 6 8 8 8 0 Olfactory marker protein Amidase02_C PF12123.8 OWF51849.1 - 2.1 8.1 7.3 1.4e+02 2.3 0.0 5.4 6 1 1 7 7 7 0 N-acetylmuramoyl-l-alanine amidase Metallophos PF00149.28 OWF51850.1 - 4.3e-38 131.9 0.0 6.7e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OWF51850.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) PTEN_C2 PF10409.9 OWF51850.1 - 0.094 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein RAWUL PF16207.5 OWF51851.1 - 8e-24 84.1 0.0 1.4e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 OWF51851.1 - 2.2e-16 59.4 10.9 3.8e-16 58.6 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF51851.1 - 4.6e-10 39.2 11.0 7.8e-10 38.5 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51851.1 - 3.3e-09 36.9 9.1 5.6e-09 36.2 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF51851.1 - 5.2e-08 32.6 8.3 7.7e-08 32.1 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF51851.1 - 2.5e-06 27.4 8.7 4.9e-06 26.5 8.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF51851.1 - 1.2e-05 25.1 9.2 2.1e-05 24.4 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF51851.1 - 2.7e-05 24.2 8.1 5.1e-05 23.4 8.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OWF51851.1 - 0.0001 22.1 5.7 0.00018 21.2 5.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OWF51851.1 - 0.00027 20.7 7.0 0.0006 19.6 7.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 OWF51851.1 - 0.0013 18.6 3.5 0.0027 17.6 3.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OWF51851.1 - 0.0021 18.3 7.7 0.0057 16.9 7.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-UDP PF14569.6 OWF51851.1 - 0.0031 17.6 0.6 0.049 13.7 2.2 2.0 2 0 0 2 2 2 1 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OWF51851.1 - 0.059 13.3 8.9 0.72 9.8 9.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 OWF51851.1 - 0.066 13.1 7.7 0.24 11.3 7.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF51851.1 - 0.24 11.2 4.6 0.59 9.9 4.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 OWF51851.1 - 0.7 10.1 7.2 1.3 9.2 7.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-MIZ PF02891.20 OWF51851.1 - 1.7 8.4 7.5 3.7 7.4 7.5 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C4_Topoisom PF01396.19 OWF51851.1 - 2.5 7.9 5.2 0.28 11.0 0.9 1.6 2 0 0 2 2 1 0 Topoisomerase DNA binding C4 zinc finger cNMP_binding PF00027.29 OWF51852.1 - 9e-24 83.4 0.1 8.1e-17 61.1 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ras PF00071.22 OWF51853.1 - 3.4e-43 147.0 0.0 4.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF51853.1 - 1.9e-15 57.1 0.0 3.7e-15 56.2 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OWF51853.1 - 8.2e-06 25.5 0.0 0.00055 19.5 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OWF51853.1 - 1.5e-05 24.6 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF51853.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF51853.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 OWF51853.1 - 0.052 13.0 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 OWF51853.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 OWF51853.1 - 0.13 12.3 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain DNA_pol_B_3 PF08408.10 OWF51854.1 - 4.4 7.5 4.5 1e+02 3.1 0.3 3.0 3 0 0 3 3 3 0 DNA polymerase family B viral insert Metallophos PF00149.28 OWF51855.1 - 3.7e-14 53.7 0.0 6e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF51855.1 - 0.0001 22.5 0.0 0.0084 16.3 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OWF51856.1 - 3.6e-12 47.2 0.0 5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF51856.1 - 0.0008 19.6 0.0 0.029 14.6 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OWF51857.1 - 7.5e-14 52.7 0.0 1.1e-13 52.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MIOX PF05153.15 OWF51858.1 - 3.9e-112 373.9 2.7 4.5e-112 373.6 2.7 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 OWF51858.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 HD domain SPARC_Ca_bdg PF10591.9 OWF51859.1 - 1.4e-18 67.3 5.4 1.4e-18 67.3 5.4 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 OWF51859.1 - 1.8e-11 43.5 3.7 1.8e-11 43.5 3.7 2.7 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat EF-hand_1 PF00036.32 OWF51859.1 - 0.001 18.4 0.1 1.4 8.7 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF51859.1 - 0.0013 19.2 0.5 0.0051 17.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF51859.1 - 0.019 14.8 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain LRR_9 PF14580.6 OWF51860.1 - 1.9e-07 30.8 4.1 4.9e-07 29.4 4.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF51860.1 - 4.1e-06 27.0 15.8 0.0013 19.1 0.8 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF51860.1 - 0.0022 17.7 10.8 0.084 12.6 0.0 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 OWF51860.1 - 0.66 10.2 3.3 3 8.1 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 OWF51860.1 - 5.2 8.0 8.8 68 4.6 0.0 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat Linker_histone PF00538.19 OWF51861.1 - 2.8e-39 133.3 0.7 3.6e-14 52.9 0.1 3.6 3 0 0 3 3 3 3 linker histone H1 and H5 family RFX_DNA_binding PF02257.15 OWF51861.1 - 0.00026 21.6 0.0 0.0005 20.6 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Hid1 PF12722.7 OWF51861.1 - 0.52 8.4 15.6 0.68 8.0 15.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 OWF51861.1 - 3.6 6.9 11.2 7.3 5.8 11.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 OWF51861.1 - 5.2 5.2 33.3 12 4.1 33.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 OWF51861.1 - 6.3 5.2 31.3 9.8 4.5 31.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RPN7 PF10602.9 OWF51862.1 - 4.1e-63 212.2 1.1 9.2e-63 211.1 1.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OWF51862.1 - 3.6e-19 69.2 0.9 3e-17 63.1 0.1 2.6 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 OWF51862.1 - 0.011 15.8 2.8 0.57 10.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TAF6_C PF07571.13 OWF51862.1 - 0.083 13.2 0.0 6 7.3 0.0 3.2 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain DnaGprimase_HBD PF16730.5 OWF51862.1 - 0.19 11.8 1.1 26 4.9 0.0 3.3 3 1 1 4 4 4 0 DnaG-primase C-terminal, helicase-binding domain V_ATPase_I PF01496.19 OWF51863.1 - 0 1067.2 3.5 0 1067.0 3.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family EVI2A PF05399.11 OWF51863.1 - 0.55 9.8 2.2 3.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Dus PF01207.17 OWF51864.1 - 2.2e-74 250.4 0.0 3.8e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF702 PF05142.12 OWF51864.1 - 0.01 16.3 8.5 0.01 16.3 8.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF702) SOR_SNZ PF01680.17 OWF51864.1 - 0.017 14.9 0.0 0.14 11.9 0.0 2.0 1 1 1 2 2 2 0 SOR/SNZ family ThiG PF05690.14 OWF51864.1 - 0.018 14.3 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 OWF51864.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Peptidase_C97 PF05903.14 OWF51865.1 - 3.8e-37 127.5 0.0 8.8e-37 126.3 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain RNA_pol_Rpb1_3 PF04983.18 OWF51865.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 WD40 PF00400.32 OWF51866.1 - 8.8e-61 200.4 36.8 2.3e-07 31.4 0.2 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 OWF51866.1 - 2.9e-43 147.2 2.7 2.9e-43 147.2 2.7 2.2 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OWF51866.1 - 1.8e-19 69.8 14.7 0.0037 17.5 0.0 8.1 4 3 5 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OWF51866.1 - 0.00015 20.4 2.2 0.0004 19.0 0.1 2.5 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 OWF51866.1 - 0.0003 19.7 10.2 1.3 7.7 0.1 6.4 4 3 3 7 7 7 2 Nup133 N terminal like WD40_like PF17005.5 OWF51866.1 - 0.00081 18.8 5.2 0.13 11.6 0.0 4.3 1 1 1 4 4 4 1 WD40-like domain Diphthami_syn_2 PF01902.17 OWF51866.1 - 0.012 15.1 1.4 3.6 7.0 0.0 3.8 4 1 0 4 4 4 0 Diphthamide synthase UTP15_C PF09384.10 OWF51866.1 - 0.018 14.8 1.6 0.032 13.9 1.6 1.4 1 0 0 1 1 1 0 UTP15 C terminal Osteopontin PF00865.18 OWF51866.1 - 0.19 11.2 24.3 0.79 9.2 23.4 2.1 2 0 0 2 2 2 0 Osteopontin YL1 PF05764.13 OWF51866.1 - 0.28 11.3 24.3 0.52 10.4 24.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein zf-C3HC4_2 PF13923.6 OWF51867.1 - 9.3e-07 28.6 20.2 2.7e-06 27.1 20.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51867.1 - 2.1e-06 27.9 20.8 8.5e-06 26.0 20.8 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF51867.1 - 1.8e-05 24.5 16.4 5.1e-05 23.1 16.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 OWF51867.1 - 2.6e-05 24.3 4.0 6.9e-05 22.9 4.0 1.7 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4 PF00097.25 OWF51867.1 - 0.00023 21.0 21.4 0.00074 19.3 21.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 OWF51867.1 - 0.00071 20.2 5.4 0.00071 20.2 5.4 3.3 2 1 1 3 3 2 2 TRAF-type zinc finger zf-rbx1 PF12678.7 OWF51867.1 - 0.0016 18.7 15.2 0.0068 16.7 15.2 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OWF51867.1 - 0.0031 17.4 16.5 0.013 15.4 16.5 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OWF51867.1 - 0.02 14.9 18.7 0.069 13.2 18.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger KxDL PF10241.9 OWF51867.1 - 0.1 12.9 0.8 0.28 11.5 0.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4482 PF14818.6 OWF51867.1 - 0.56 11.1 0.0 0.56 11.1 0.0 4.1 4 2 0 4 4 3 0 Domain of unknown function (DUF4482) zf-RING_5 PF14634.6 OWF51867.1 - 0.88 9.6 17.3 3.5 7.7 17.3 2.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OWF51867.1 - 1.3 9.3 18.8 3.8 7.8 18.8 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Phosphodiest PF01663.22 OWF51868.1 - 1.5e-78 264.9 2.9 1.8e-78 264.6 2.9 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF51868.1 - 2.1e-12 47.1 0.0 3.3e-05 23.5 0.0 2.5 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 OWF51868.1 - 2.3e-05 23.9 0.0 4.6e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF3746 PF12562.8 OWF51868.1 - 0.054 13.4 3.1 0.29 11.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) Dynactin PF12455.8 OWF51868.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Dynein associated protein zf-LITAF-like PF10601.9 OWF51869.1 - 6.1e-26 90.5 10.2 8.6e-26 90.0 10.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 OWF51869.1 - 0.04 13.9 0.9 2 8.4 0.0 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon RRM_1 PF00076.22 OWF51871.1 - 2.9e-05 23.8 0.0 7.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OWF51871.1 - 0.0062 16.3 0.0 0.021 14.6 0.0 1.9 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Orthopox_A5L PF06193.11 OWF51871.1 - 2.9 7.3 6.8 0.28 10.6 1.9 1.7 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like AMP-binding PF00501.28 OWF51872.1 - 1.3e-101 340.3 0.0 1.7e-101 339.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF51872.1 - 7.6e-05 23.6 0.0 0.00018 22.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HSNSD PF12062.8 OWF51873.1 - 6.4e-162 539.7 1.4 1e-161 539.0 1.4 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 OWF51873.1 - 5.2e-36 124.5 0.0 5.2e-36 124.5 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF51873.1 - 1e-08 35.8 2.2 0.0026 18.2 0.1 2.8 2 1 1 3 3 3 2 Sulfotransferase family Histone PF00125.24 OWF51874.1 - 2.9e-38 131.2 0.7 3.6e-38 130.9 0.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OWF51874.1 - 0.00043 20.6 0.0 0.00067 20.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OWF51874.1 - 0.0015 18.6 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OWF51874.1 - 0.0066 16.7 0.1 0.011 16.0 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UCH PF00443.29 OWF51875.1 - 4.5e-19 69.0 1.1 1.3e-18 67.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HNH_5 PF14279.6 OWF51875.1 - 8.2 6.4 8.4 4.2 7.3 4.0 2.5 2 0 0 2 2 2 0 HNH endonuclease ZU5 PF00791.20 OWF51877.1 - 0.037 14.4 0.0 0.098 13.0 0.0 1.7 1 0 0 1 1 1 0 ZU5 domain Gal-3-0_sulfotr PF06990.11 OWF51879.1 - 7.5e-53 179.8 3.0 9.8e-53 179.5 3.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF51879.1 - 6.1e-07 29.6 2.1 2.6e-06 27.5 2.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family RRM_1 PF00076.22 OWF51880.1 - 9.6e-43 143.9 0.0 1.3e-14 53.7 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF51880.1 - 0.00049 19.9 0.0 2.4 8.1 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OWF51880.1 - 0.0005 20.0 0.2 0.52 10.3 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OWF51880.1 - 0.0015 18.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OWF51880.1 - 0.017 15.2 0.0 0.31 11.1 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 UPF0047 PF01894.17 OWF51881.1 - 3e-36 124.1 0.0 3.5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 7tm_1 PF00001.21 OWF51882.1 - 1.2e-57 195.3 21.1 1.5e-57 194.9 21.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 OWF51882.1 - 1e-11 44.8 16.6 1.5e-11 44.2 16.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 OWF51882.1 - 2.3e-07 30.8 16.3 2.3e-07 30.8 16.3 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF51882.1 - 4.8e-06 26.5 8.7 4.8e-06 26.5 8.7 1.6 2 0 0 2 2 2 1 Olfactory receptor PRIMA1 PF16101.5 OWF51882.1 - 4.5 7.3 5.7 14 5.8 2.5 2.8 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 OWF51883.1 - 5.5e-24 84.9 0.0 6.1e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Granulin PF00396.18 OWF51884.1 - 1.7e-155 505.1 459.3 5.3e-14 52.3 23.5 23.9 16 10 8 24 24 24 20 Granulin MTS_N PF08468.11 OWF51884.1 - 0.3 11.1 1.4 2.5e+02 1.6 0.0 4.5 6 0 0 6 6 6 0 Methyltransferase small domain N-terminal Kazal_2 PF07648.15 OWF51885.1 - 8.8e-09 35.4 35.6 3.9e-05 23.7 1.7 6.3 4 1 1 5 5 5 3 Kazal-type serine protease inhibitor domain Pacifastin_I PF05375.13 OWF51885.1 - 1.2e-07 31.3 2.9 1.2e-07 31.3 2.9 4.8 3 0 0 3 3 3 1 Pacifastin inhibitor (LCMII) Kazal_1 PF00050.21 OWF51885.1 - 1.1e-06 28.6 31.7 0.0011 19.0 3.6 5.4 3 1 1 4 4 4 3 Kazal-type serine protease inhibitor domain BRCT PF00533.26 OWF51886.1 - 2.5e-14 53.4 0.1 2.8e-07 30.8 0.0 3.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OWF51886.1 - 1.2e-10 41.6 0.0 1e-05 25.8 0.0 3.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4 PF00097.25 OWF51886.1 - 2.8e-07 30.3 4.5 2.8e-07 30.3 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF51886.1 - 1.2e-05 25.4 4.1 2.9e-05 24.1 4.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF51886.1 - 8.9e-05 22.3 5.7 0.00025 20.8 5.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51886.1 - 0.00017 21.8 4.4 0.00052 20.3 4.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF51886.1 - 0.0002 21.2 3.1 0.0005 19.9 3.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF51886.1 - 0.00042 20.2 3.8 0.0014 18.6 3.8 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 OWF51886.1 - 0.0016 18.2 2.5 0.0046 16.7 2.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OWF51886.1 - 0.0042 17.3 3.0 0.017 15.4 3.0 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OWF51886.1 - 0.03 14.2 2.4 0.096 12.6 2.4 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OWF51886.1 - 0.23 11.3 5.2 0.2 11.5 3.4 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Val_tRNA-synt_C PF10458.9 OWF51886.1 - 0.29 11.4 4.5 0.68 10.3 2.3 2.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm zf-RING_UBOX PF13445.6 OWF51886.1 - 0.45 10.6 5.7 0.6 10.2 4.1 2.2 1 1 0 1 1 1 0 RING-type zinc-finger NARG2_C PF10505.9 OWF51887.1 - 3.1e-46 157.6 0.0 1.6e-45 155.2 0.0 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus AT_hook PF02178.19 OWF51887.1 - 0.085 12.8 17.6 1.6 8.9 6.5 3.2 2 0 0 2 2 2 0 AT hook motif Enkurin PF13864.6 OWF51888.1 - 9e-29 99.8 4.8 9e-29 99.8 4.8 2.3 3 1 0 3 3 3 1 Calmodulin-binding OmpH PF03938.14 OWF51888.1 - 0.3 11.4 3.8 0.58 10.5 3.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spectrin_like PF18373.1 OWF51888.1 - 0.33 11.1 2.1 0.71 10.0 0.2 2.4 2 1 0 2 2 2 0 Spectrin like domain Pkinase PF00069.25 OWF51889.1 - 1.7e-57 194.8 0.0 2.1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51889.1 - 3.7e-43 147.7 0.1 5.3e-43 147.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 OWF51889.1 - 1.6e-20 73.1 0.7 4.3e-20 71.7 0.7 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 OWF51889.1 - 7e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OWF51889.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF51889.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRR18 PF15671.5 OWF51889.1 - 1.5 8.6 8.6 2.5 7.9 8.6 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 Totivirus_coat PF05518.11 OWF51889.1 - 4 5.4 7.9 5.7 4.9 7.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein Pex2_Pex12 PF04757.14 OWF51890.1 - 1.1e-33 116.7 3.7 1.3e-33 116.5 3.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OWF51890.1 - 1.5e-10 40.7 12.9 3.1e-10 39.8 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF51890.1 - 3.4e-09 36.9 17.1 3.4e-09 36.9 17.1 1.7 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 OWF51890.1 - 1.7e-08 34.2 12.0 2.9e-08 33.5 12.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OWF51890.1 - 1.3e-07 31.4 15.9 2.9e-07 30.2 15.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF51890.1 - 1.8e-07 30.9 16.3 3.6e-07 29.9 16.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF51890.1 - 9.4e-06 25.8 12.8 9.4e-06 25.8 12.8 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF51890.1 - 8.8e-05 22.4 11.6 9.1e-05 22.4 9.8 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF51890.1 - 0.00016 21.6 14.0 0.00036 20.4 14.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF51890.1 - 0.028 14.4 7.3 0.037 14.1 6.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OWF51890.1 - 0.17 12.0 15.7 0.11 12.7 13.6 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OWF51890.1 - 0.38 10.6 11.8 0.79 9.6 11.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 OWF51890.1 - 0.71 10.0 9.4 1.9 8.6 9.4 1.7 1 0 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 OWF51890.1 - 0.88 9.4 10.9 0.48 10.2 5.2 3.1 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_10 PF16685.5 OWF51890.1 - 1.9 8.7 10.8 3.7 7.8 10.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 EF-hand_6 PF13405.6 OWF51891.1 - 2.8e-15 54.9 5.6 8.1e-06 25.4 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 OWF51891.1 - 3.6e-15 54.3 8.6 2.1e-05 23.8 0.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OWF51891.1 - 3.8e-15 56.1 11.1 2.1e-11 44.1 3.6 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF51891.1 - 3.1e-11 42.2 5.1 0.00032 20.1 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OWF51891.1 - 6.4e-07 29.1 8.8 0.0013 18.5 2.6 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_3 PF09069.11 OWF51891.1 - 0.00011 22.5 0.5 0.0062 16.9 0.2 2.3 2 0 0 2 2 2 1 EF-hand SPARC_Ca_bdg PF10591.9 OWF51891.1 - 0.00088 19.6 2.4 0.33 11.3 0.9 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region KIP1 PF07765.12 OWF51891.1 - 0.48 10.6 5.4 0.78 9.9 0.1 2.8 2 1 1 3 3 3 0 KIP1-like protein SRF-TF PF00319.18 OWF51892.1 - 0.83 9.2 20.5 13 5.4 0.3 6.9 2 1 4 7 7 7 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Ig_3 PF13927.6 OWF51894.1 - 7.2e-10 39.3 0.7 2.2e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 OWF51894.1 - 6.6e-07 29.4 1.8 0.0022 18.1 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF51894.1 - 2.4e-05 24.3 0.0 0.025 14.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_5 PF16681.5 OWF51894.1 - 0.0064 16.9 0.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Syndecan PF01034.20 OWF51894.1 - 0.18 11.8 1.1 0.55 10.2 0.4 2.1 2 0 0 2 2 2 0 Syndecan domain Herpes_IE2_3 PF03361.14 OWF51895.1 - 0.024 14.5 0.3 0.065 13.1 0.2 1.8 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Como_SCP PF02248.16 OWF51895.1 - 0.03 13.9 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Small coat protein 7tm_1 PF00001.21 OWF51896.1 - 2e-38 132.2 21.2 2.5e-38 131.9 21.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF51896.1 - 6.5e-14 52.3 15.3 1.6e-13 51.1 15.3 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srab PF10292.9 OWF51896.1 - 0.0017 17.3 8.3 0.0027 16.7 8.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor 7TM_GPCR_Srx PF10328.9 OWF51896.1 - 0.015 14.9 20.0 0.017 14.8 19.1 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx BRI3BP PF14965.6 OWF51896.1 - 3.8 7.0 9.8 0.63 9.5 4.7 2.0 1 1 1 2 2 2 0 Negative regulator of p53/TP53 DUF4205 PF13898.6 OWF51897.1 - 2.2e-91 306.4 0.1 4.5e-89 298.8 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) PA PF02225.22 OWF51898.1 - 3.2e-05 23.8 0.1 6.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 OWF51898.1 - 0.0036 17.0 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 OWF51898.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain STAG PF08514.11 OWF51899.1 - 1.8e-38 130.9 0.4 1.8e-38 130.9 0.4 3.5 4 0 0 4 4 4 1 STAG domain HMG_CoA_synt_N PF01154.17 OWF51899.1 - 0.17 11.8 0.0 0.64 9.9 0.0 1.9 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF406 PF04175.12 OWF51899.1 - 0.52 10.8 3.6 11 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF406) MerR-DNA-bind PF09278.11 OWF51899.1 - 0.58 10.7 5.0 2.7 8.6 2.0 2.8 2 0 0 2 2 2 0 MerR, DNA binding Mab-21 PF03281.14 OWF51902.1 - 3.4e-29 102.1 0.2 5.7e-29 101.3 0.2 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_2 PF07719.17 OWF51902.1 - 0.0021 18.0 0.0 3.6 7.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF51902.1 - 0.0075 16.5 0.3 7.3 7.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF51902.1 - 0.05 13.4 0.0 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF51902.1 - 0.17 12.0 0.1 31 4.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat YhdX PF17444.2 OWF51903.1 - 5e-09 35.8 52.7 5.1 7.0 0.1 16.3 18 0 0 18 18 18 8 Uncharacterized YhdX-like p6 PF17548.2 OWF51903.1 - 0.00061 19.7 25.6 1.8 8.6 0.3 9.0 1 1 7 9 9 9 4 Histone-like Protein p6 ODC_AZ PF02100.17 OWF51903.1 - 0.013 15.4 6.7 24 4.9 0.1 5.4 1 1 5 6 6 6 0 Ornithine decarboxylase antizyme INPP5B_PH PF16776.5 OWF51903.1 - 1.2 8.8 12.4 12 5.7 0.3 5.2 1 1 8 9 9 9 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain zf-CCHC PF00098.23 OWF51904.1 - 0.008 16.2 0.3 0.021 14.9 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OWF51904.1 - 0.15 11.8 1.1 0.32 10.8 1.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 OWF51904.1 - 0.44 10.3 3.7 0.15 11.8 0.6 1.9 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 OWF51904.1 - 0.69 9.8 3.5 1.9 8.4 3.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Packaging_FI PF14000.6 OWF51905.1 - 0.29 11.6 0.4 1.3e+02 3.0 0.0 3.6 1 1 2 4 4 4 0 DNA packaging protein FI Tfb2_C PF18307.1 OWF51906.1 - 0.017 15.6 13.7 1.3 9.5 0.9 4.3 1 1 2 4 4 4 0 Transcription factor Tfb2 (p52) C-terminal domain Phage_ABA_S PF18066.1 OWF51906.1 - 0.33 11.6 7.9 65 4.3 1.1 4.5 1 1 1 2 2 2 0 Phage ABA sandwich domain SVS_QK PF10578.9 OWF51907.1 - 5.7 7.8 19.6 1e+02 3.9 0.1 6.4 7 0 0 7 7 7 0 Seminal vesicle protein repeat Leu_leader PF08054.11 OWF51907.1 - 7.9 6.2 23.7 5.7 6.6 0.2 6.8 8 0 0 8 8 8 0 Leucine operon leader peptide F-box_4 PF15966.5 OWF51908.1 - 2.9e-25 88.4 2.7 1.1e-15 57.6 0.1 2.6 1 1 1 2 2 2 2 F-box zf-TRAF_2 PF15965.5 OWF51908.1 - 3.4e-20 72.3 19.2 3.4e-20 72.3 19.2 2.0 3 0 0 3 3 3 1 TRAF-like zinc-finger F-box PF00646.33 OWF51908.1 - 1.3e-05 25.0 1.0 3.2e-05 23.7 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OWF51908.1 - 1.4e-05 24.8 1.9 3.5e-05 23.6 1.9 1.7 1 0 0 1 1 1 1 F-box-like Aph-1 PF06105.12 OWF51909.1 - 1.1e-92 309.7 18.5 1.2e-92 309.5 18.5 1.0 1 0 0 1 1 1 1 Aph-1 protein F-box_4 PF15966.5 OWF51910.1 - 1.2e-34 118.6 1.3 2.8e-34 117.4 0.6 2.0 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 OWF51910.1 - 6.1e-33 113.2 16.7 6.1e-33 113.2 16.7 2.6 2 1 0 2 2 2 1 TRAF-like zinc-finger zf-TRAF PF02176.18 OWF51910.1 - 2.6e-05 24.8 19.7 0.00065 20.3 3.5 3.9 3 1 1 4 4 4 2 TRAF-type zinc finger F-box-like PF12937.7 OWF51910.1 - 0.00059 19.7 2.3 0.00059 19.7 2.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OWF51910.1 - 0.0012 18.7 4.3 0.0012 18.7 4.3 1.9 2 0 0 2 2 2 1 F-box domain zf-ACC PF17848.1 OWF51910.1 - 3.7 7.7 6.0 1.4 9.1 1.1 3.0 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Sina PF03145.16 OWF51910.1 - 3.9 7.4 11.1 0.053 13.5 2.0 2.4 1 1 1 2 2 2 0 Seven in absentia protein family Zfx_Zfy_act PF04704.13 OWF51911.1 - 8.8e-09 34.9 73.9 2.7 7.0 5.1 10.5 1 1 3 4 4 4 1 Zfx / Zfy transcription activation region zf-B_box PF00643.24 OWF51912.1 - 0.0034 17.5 8.2 0.0073 16.4 8.2 1.6 1 0 0 1 1 1 1 B-box zinc finger HeLo PF14479.6 OWF51912.1 - 0.016 15.0 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation S1 PF00575.23 OWF51913.1 - 2e-12 47.2 0.2 2e-12 47.2 0.2 1.8 2 0 0 2 2 2 1 S1 RNA binding domain zf-CCHC PF00098.23 OWF51913.1 - 0.00045 20.2 5.3 0.00088 19.2 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle FGF-BP1 PF06473.12 OWF51913.1 - 0.41 10.4 16.1 3.1 7.6 11.8 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) DUF4820 PF16091.5 OWF51913.1 - 1.7 8.0 8.8 2.9 7.2 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4228 PF14009.6 OWF51913.1 - 2 8.8 12.2 1.2 9.5 10.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) RR_TM4-6 PF06459.12 OWF51913.1 - 4.9 6.9 22.0 8.7 6.1 21.7 1.7 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 FYVE PF01363.21 OWF51914.1 - 1.1e-19 70.3 8.0 2.2e-19 69.4 8.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 OWF51914.1 - 1.6e-08 35.0 0.5 3.1e-08 34.1 0.2 1.6 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 OWF51914.1 - 0.0018 18.5 5.9 0.003 17.8 5.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger IQ_SEC7_PH PF16453.5 OWF51914.1 - 0.0019 18.2 0.2 0.0033 17.4 0.2 1.3 1 0 0 1 1 1 1 PH domain Relaxase PF03432.14 OWF51914.1 - 0.0036 16.9 0.1 0.0051 16.4 0.1 1.2 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain PH_13 PF16652.5 OWF51914.1 - 0.0045 16.8 1.3 0.09 12.6 1.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Zn_ribbon_SprT PF17283.2 OWF51914.1 - 3.6 7.6 13.5 1.9 8.5 10.4 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF2650 PF10853.8 OWF51915.1 - 0.0028 17.3 9.5 0.03 14.0 3.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2650) Thiolase_N PF00108.23 OWF51916.1 - 1.7e-87 293.1 0.8 2.3e-87 292.7 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OWF51916.1 - 1.1e-44 151.1 0.9 1.1e-44 151.1 0.9 1.9 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OWF51916.1 - 8.3e-06 25.6 4.3 0.00024 20.8 1.3 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 OWF51916.1 - 0.00077 18.3 1.2 0.072 11.8 0.0 2.1 2 0 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) DUF963 PF06131.11 OWF51918.1 - 6.4e-13 47.9 67.5 0.27 10.7 0.1 14.4 3 2 10 15 15 15 14 Schizosaccharomyces pombe repeat of unknown function (DUF963) Hexapep PF00132.24 OWF51918.1 - 0.57 10.0 23.1 42 4.1 0.1 9.5 7 2 1 9 9 9 0 Bacterial transferase hexapeptide (six repeats) Cu2_monooxygen PF01082.20 OWF51919.1 - 3e-22 79.2 0.3 5.5e-22 78.4 0.3 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF51919.1 - 4e-18 65.4 0.0 8.1e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DUF5374 PF17344.2 OWF51919.1 - 0.094 12.6 0.0 4.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5374) MFAP1 PF06991.11 OWF51920.1 - 3.7e-71 239.4 25.5 3.7e-71 239.4 25.5 2.5 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing CAP PF00188.26 OWF51920.1 - 5e-20 72.6 1.4 1.1e-19 71.5 1.4 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase PF00069.25 OWF51921.1 - 3.3e-50 170.9 0.0 5e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF51921.1 - 2.1e-28 99.3 0.0 3.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF51921.1 - 0.0052 16.1 0.0 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF51921.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OWF51921.1 - 0.046 13.1 0.4 0.088 12.2 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OWF51921.1 - 0.075 12.0 0.2 0.16 11.0 0.2 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Spt5-NGN PF03439.13 OWF51922.1 - 5.5e-25 87.1 0.1 1.2e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 OWF51922.1 - 1.2e-22 79.1 14.5 9.9e-08 31.7 0.3 5.4 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.8 OWF51922.1 - 2.3e-13 51.0 7.0 2.3e-13 51.0 7.0 2.5 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 OWF51922.1 - 2.3e-08 34.4 13.9 2.3e-08 34.4 13.9 3.4 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF150_C PF17384.2 OWF51922.1 - 0.0023 18.0 0.5 5.5 7.2 0.1 3.7 4 0 0 4 4 4 2 RimP C-terminal SH3 domain DUF3912 PF13051.6 OWF51922.1 - 0.0067 16.7 0.1 0.057 13.7 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) PPV_E1_N PF00524.18 OWF51922.1 - 0.71 10.3 5.3 1.9 9.0 5.3 1.7 1 0 0 1 1 1 0 E1 Protein, N terminal domain zf-CCCH PF00642.24 OWF51923.1 - 2.1e-11 43.4 12.8 6.3e-05 22.8 2.8 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF51923.1 - 3.4e-10 39.6 22.9 0.00014 21.8 5.7 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 OWF51923.1 - 2.4e-07 30.4 19.6 0.01 15.6 0.7 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 OWF51923.1 - 0.00019 21.6 10.7 0.029 14.6 3.0 3.0 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 OWF51923.1 - 0.0019 18.6 21.7 0.0062 17.0 1.9 3.5 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OWF51923.1 - 0.0056 17.4 0.3 0.0056 17.4 0.3 3.8 2 1 1 3 3 3 2 Torus domain Neur_chan_LBD PF02931.23 OWF51924.1 - 7.7e-48 162.8 1.5 1.1e-47 162.3 1.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51924.1 - 3.6e-17 63.2 7.8 1.4e-13 51.4 1.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region 7tm_1 PF00001.21 OWF51925.1 - 6.4e-08 32.2 1.7 6.4e-08 32.2 1.7 2.9 2 1 1 3 3 3 1 7 transmembrane receptor (rhodopsin family) FAM199X PF15814.5 OWF51926.1 - 1.9e-33 115.9 23.8 1.8e-25 89.7 10.5 2.1 1 1 1 2 2 2 2 Protein family FAM199X Phage_min_cap2 PF06152.11 OWF51926.1 - 0.057 12.3 2.2 0.083 11.8 2.2 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 CMV_1a PF12467.8 OWF51926.1 - 0.1 12.9 1.7 14 6.0 0.0 2.4 1 1 1 2 2 2 0 Cucumber mosaic virus 1a protein family Adipokin_hormo PF06377.11 OWF51927.1 - 0.27 11.6 34.5 10 6.6 0.0 9.6 9 1 0 9 9 9 0 Adipokinetic hormone FSIP2 PF15783.5 OWF51927.1 - 0.31 8.9 0.0 0.38 8.6 0.0 1.0 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Bclt PF15318.6 OWF51928.1 - 3.2 7.6 6.3 15 5.3 0.1 3.4 1 1 3 4 4 4 0 Putative Bcl-2 like protein of testis Ras PF00071.22 OWF51929.1 - 8.3e-40 136.0 0.0 1.1e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF51929.1 - 2.1e-13 50.6 0.0 4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OWF51929.1 - 2.7e-06 27.5 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OWF51929.1 - 3.4e-06 26.6 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF51929.1 - 1.8e-05 24.7 0.0 0.00098 19.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OWF51929.1 - 0.017 14.6 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OWF51929.1 - 0.03 13.9 0.0 2.3 7.7 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 OWF51929.1 - 0.034 14.4 0.2 1.4 9.2 0.0 2.7 1 1 1 2 2 2 0 AAA domain DUF4562 PF15123.6 OWF51930.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) Chromo PF00385.24 OWF51931.1 - 1.2e-07 31.5 0.5 3.7e-07 30.0 0.3 1.8 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Homeodomain PF00046.29 OWF51932.1 - 7.1e-21 73.8 2.8 1.2e-20 73.0 2.8 1.4 1 0 0 1 1 1 1 Homeodomain DUF2986 PF11661.8 OWF51932.1 - 0.011 16.3 0.6 0.011 16.3 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 OWF51932.1 - 0.014 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 OWF51932.1 - 0.17 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CARD PF00619.21 OWF51933.1 - 5.4e-07 29.6 0.2 2.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Caspase recruitment domain Peptidase_C14 PF00656.22 OWF51933.1 - 6.7e-05 23.0 0.2 0.00043 20.3 0.2 2.1 1 1 0 1 1 1 1 Caspase domain CARD_2 PF16739.5 OWF51933.1 - 0.022 14.7 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Caspase recruitment domain Caprin-1_dimer PF18293.1 OWF51933.1 - 0.11 13.1 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Caprin-1 dimerization domain DUF2650 PF10853.8 OWF51933.1 - 0.13 12.0 0.6 0.3 10.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) TAF1_subA PF14929.6 OWF51933.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A PAH PF02671.21 OWF51933.1 - 0.14 12.3 0.3 0.32 11.2 0.3 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat Neur_chan_LBD PF02931.23 OWF51934.1 - 3.6e-34 118.1 0.1 4.7e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51934.1 - 1.7e-09 38.1 11.2 1.7e-09 38.1 11.2 2.3 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Doppel PF11466.8 OWF51934.1 - 0.73 9.5 3.2 4.3 7.1 0.3 2.6 2 0 0 2 2 2 0 Prion-like protein Doppel Neur_chan_LBD PF02931.23 OWF51935.1 - 2.7e-33 115.2 0.0 3.6e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF51935.1 - 2.1e-09 37.8 11.1 2.1e-09 37.8 11.1 2.3 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Doppel PF11466.8 OWF51935.1 - 0.72 9.6 3.2 4.3 7.1 0.3 2.6 2 0 0 2 2 2 0 Prion-like protein Doppel EMI PF07546.13 OWF51936.1 - 0.00036 21.2 4.7 0.00098 19.8 4.7 1.8 1 0 0 1 1 1 1 EMI domain TRAP_alpha PF03896.16 OWF51936.1 - 0.0068 15.6 0.8 0.06 12.5 0.1 2.0 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit TMEM154 PF15102.6 OWF51936.1 - 0.02 14.8 0.8 0.02 14.8 0.8 2.4 1 1 1 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 OWF51936.1 - 0.025 15.4 0.3 0.44 11.4 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OWF51936.1 - 0.025 15.3 0.2 0.087 13.6 0.0 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal PRIMA1 PF16101.5 OWF51936.1 - 0.11 12.6 1.5 0.21 11.6 0.3 2.0 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 ECSCR PF15820.5 OWF51936.1 - 10 6.0 9.8 2.5 7.9 3.8 2.6 1 1 2 3 3 3 0 Endothelial cell-specific chemotaxis regulator TMEM154 PF15102.6 OWF51937.1 - 7e-05 22.8 2.1 7e-05 22.8 2.1 1.7 1 1 1 2 2 2 1 TMEM154 protein family SKG6 PF08693.10 OWF51937.1 - 0.03 13.7 1.1 0.058 12.8 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RIFIN PF02009.16 OWF51937.1 - 0.096 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Rifin DUF1180 PF06679.12 OWF51937.1 - 0.39 11.1 5.3 1 9.7 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Glycophorin_A PF01102.18 OWF51937.1 - 0.81 9.9 5.8 2.4 8.4 5.8 1.8 1 1 0 1 1 1 0 Glycophorin A Tetraspanin PF00335.20 OWF51938.1 - 7.2e-39 133.8 12.6 8.5e-39 133.6 12.6 1.0 1 0 0 1 1 1 1 Tetraspanin family AmpE PF17113.5 OWF51938.1 - 0.021 14.2 0.6 0.021 14.2 0.6 1.8 2 0 0 2 2 2 0 Regulatory signalling modulator protein AmpE TMEM154 PF15102.6 OWF51938.1 - 0.3 11.0 3.1 0.26 11.2 0.6 2.0 2 0 0 2 2 2 0 TMEM154 protein family Sensor PF13796.6 OWF51938.1 - 1.5 8.9 10.9 2.5 8.1 1.0 3.0 3 1 0 3 3 3 0 Putative sensor PIRT PF15099.6 OWF51938.1 - 1.7 8.2 6.9 2.6 7.6 2.0 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family MFS_1 PF07690.16 OWF51938.1 - 3.2 6.6 10.9 0.6 9.0 6.5 1.8 2 0 0 2 2 2 0 Major Facilitator Superfamily CD20 PF04103.15 OWF51938.1 - 5.9 7.0 12.9 0.16 12.0 5.9 2.0 2 1 0 2 2 2 0 CD20-like family Spec3 PF15795.5 OWF51938.1 - 8.7 7.0 12.1 16 6.1 0.8 2.4 2 1 0 2 2 2 0 Ectodermal ciliogenesis protein MOZART1 PF12554.8 OWF51939.1 - 3.3e-25 87.6 1.3 3.9e-25 87.4 1.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated BORA_N PF15280.6 OWF51940.1 - 1.6e-48 165.3 1.7 1.6e-48 165.3 1.7 2.4 2 0 0 2 2 2 1 Protein aurora borealis N-terminus DUF4968 PF16338.5 OWF51940.1 - 0.12 12.7 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) TNFR_c6 PF00020.18 OWF51941.1 - 5.4e-07 29.9 3.4 5.4e-07 29.9 3.4 1.8 2 0 0 2 2 2 1 TNFR/NGFR cysteine-rich region Orf78 PF06024.12 OWF51941.1 - 0.027 14.8 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 OWF51941.1 - 0.18 10.5 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TNFR_c6 PF00020.18 OWF51942.1 - 3e-08 33.9 9.6 3e-08 33.9 9.6 2.0 2 0 0 2 2 2 1 TNFR/NGFR cysteine-rich region ECSCR PF15820.5 OWF51942.1 - 0.0012 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 OWF51942.1 - 0.0017 18.6 0.1 0.003 17.8 0.1 1.4 1 0 0 1 1 1 1 Orf78 (ac78) Sec62 PF03839.16 OWF51942.1 - 0.077 12.5 0.7 0.13 11.8 0.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ABC_membrane PF00664.23 OWF51942.1 - 0.091 12.4 0.2 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF5325 PF17259.2 OWF51942.1 - 0.62 10.0 3.2 3.5 7.6 3.2 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5325) SUR7 PF06687.12 OWF51942.1 - 1.5 8.4 4.8 2.5 7.7 4.8 1.5 1 1 0 1 1 1 0 SUR7/PalI family Troponin PF00992.20 OWF51943.1 - 1.6e-09 38.1 11.5 1.6e-09 38.1 11.5 2.6 1 1 1 2 2 2 2 Troponin zf-RING_2 PF13639.6 OWF51944.1 - 8.1e-10 38.9 7.0 2.2e-09 37.5 7.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OWF51944.1 - 1.4e-07 31.2 6.4 3.5e-07 30.0 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF51944.1 - 1.2e-06 28.2 6.4 2.7e-06 27.1 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF51944.1 - 8.3e-06 26.0 4.9 8.3e-06 26.0 4.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF51944.1 - 3.6e-05 23.7 3.1 0.00012 22.1 3.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF51944.1 - 5.3e-05 23.1 5.6 0.00011 22.0 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF51944.1 - 7e-05 22.6 4.5 0.00014 21.6 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF51944.1 - 9.2e-05 22.1 7.3 0.00024 20.8 7.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OWF51944.1 - 0.0012 18.5 6.2 0.0012 18.5 6.2 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OWF51944.1 - 0.016 15.2 1.3 0.04 14.0 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MEIOC PF15189.6 OWF51944.1 - 0.027 14.1 0.3 0.081 12.5 0.3 1.8 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC zf-C3HC4_4 PF15227.6 OWF51944.1 - 0.066 13.4 5.1 0.17 12.1 5.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF51944.1 - 0.071 13.0 5.1 0.18 11.7 5.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 OWF51944.1 - 0.54 10.6 6.7 1.2 9.5 6.7 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 OWF51944.1 - 0.79 9.6 5.3 2.6 7.9 5.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 OWF51944.1 - 0.89 9.7 4.3 2.7 8.2 4.3 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_9 PF13901.6 OWF51944.1 - 2.2 8.2 8.3 0.22 11.5 2.7 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon RCC1 PF00415.18 OWF51945.1 - 5.6e-78 257.4 29.7 3.3e-15 56.4 0.6 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF51945.1 - 2.5e-46 154.6 46.9 6.6e-08 32.2 0.5 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Kelch_5 PF13854.6 OWF51945.1 - 0.033 14.2 1.5 7.1 6.7 0.1 2.9 2 0 0 2 2 2 0 Kelch motif SBBP PF06739.11 OWF51945.1 - 0.042 13.9 0.2 0.36 10.8 0.1 2.7 2 0 0 2 2 2 0 Beta-propeller repeat Hira PF07569.11 OWF51945.1 - 0.14 11.8 1.6 42 3.8 0.1 3.4 3 1 1 4 4 4 0 TUP1-like enhancer of split CBFB_NFYA PF02045.15 OWF51946.1 - 7e-28 97.0 7.5 1.4e-27 96.1 7.5 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ras PF00071.22 OWF51947.1 - 6.5e-31 107.1 0.1 7.8e-31 106.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OWF51947.1 - 7.9e-11 41.7 0.1 9.8e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF51947.1 - 2.6e-10 40.6 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OWF51947.1 - 2e-07 30.6 0.1 9.6e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF51947.1 - 0.00032 20.6 0.2 0.048 13.6 0.0 2.2 1 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OWF51947.1 - 0.0007 19.7 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OWF51947.1 - 0.00094 19.6 0.1 0.0011 19.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 OWF51947.1 - 0.0015 18.1 0.4 0.019 14.5 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OWF51947.1 - 0.026 14.8 0.3 0.91 9.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 OWF51947.1 - 0.028 13.7 0.1 0.048 12.9 0.1 1.5 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 OWF51947.1 - 0.087 12.5 0.2 0.62 9.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain TIG_2 PF18020.1 OWF51947.1 - 0.16 12.6 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 TIG domain found in plexin Ank_2 PF12796.7 OWF51948.1 - 1.6e-56 188.8 10.6 7.5e-12 45.7 0.0 7.3 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF51948.1 - 1.4e-45 153.1 16.8 3.9e-08 33.7 0.0 10.4 6 4 6 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF51948.1 - 9.9e-40 130.0 12.9 1.2e-05 25.3 0.0 14.7 17 0 0 17 17 17 8 Ankyrin repeat Ank_5 PF13857.6 OWF51948.1 - 1.4e-37 127.3 18.1 1.2e-07 31.8 2.6 9.5 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 OWF51948.1 - 4.4e-33 112.3 21.9 0.00039 20.7 0.0 13.6 13 1 0 13 13 13 9 Ankyrin repeat SOCS_box PF07525.16 OWF51948.1 - 0.00018 21.8 0.2 0.00039 20.7 0.2 1.6 1 0 0 1 1 1 1 SOCS box Glyco_hydro_47 PF01532.20 OWF51949.1 - 5e-113 378.4 0.0 7.9e-113 377.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glucan_synthase PF02364.15 OWF51949.1 - 0.0094 14.2 1.7 0.014 13.6 1.7 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Nop14 PF04147.12 OWF51949.1 - 0.22 9.7 24.0 0.31 9.2 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family KIND PF16474.5 OWF51949.1 - 3.2 7.6 10.9 5.7 6.8 10.9 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain S10_plectin PF03501.15 OWF51950.1 - 2e-46 156.0 0.1 2.5e-46 155.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Alg6_Alg8 PF03155.15 OWF51951.1 - 1.3e-175 585.1 26.5 1.5e-175 584.9 26.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Hfq PF17209.3 OWF51952.1 - 0.00015 21.4 4.7 3.4 7.4 0.2 4.3 1 1 3 4 4 4 3 Hfq protein ITI_HC_C PF06668.12 OWF51952.1 - 0.004 16.8 4.3 13 5.4 0.0 4.2 1 1 1 4 4 4 2 Inter-alpha-trypsin inhibitor heavy chain C-terminus ER PF01133.17 OWF51952.1 - 0.0045 17.0 12.5 4.3 7.4 0.3 4.8 1 1 3 4 4 4 3 Enhancer of rudimentary CAP_C PF08603.11 OWF51952.1 - 0.12 12.0 2.9 5.6 6.6 0.3 3.0 1 1 2 3 3 3 0 Adenylate cyclase associated (CAP) C terminal Homeodomain PF00046.29 OWF51953.1 - 6.8e-24 83.5 1.8 8.1e-24 83.2 0.5 1.8 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 OWF51953.1 - 8.7e-07 28.6 1.4 2.9e-06 26.9 1.4 2.0 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF51953.1 - 0.0004 20.2 0.8 0.0009 19.1 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Herpes_LMP1 PF05297.11 OWF51953.1 - 3.1 6.9 4.9 4.5 6.4 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DNA_pol_phi PF04931.13 OWF51953.1 - 9.3 4.2 7.6 12 3.9 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi KIAA1430 PF13879.6 OWF51954.1 - 3.7e-25 88.6 4.4 3.7e-25 88.6 4.4 1.9 2 0 0 2 2 2 1 KIAA1430 homologue Tektin PF03148.14 OWF51955.1 - 1.4e-139 465.1 29.5 1.6e-139 464.9 29.5 1.0 1 0 0 1 1 1 1 Tektin family MitMem_reg PF13012.6 OWF51955.1 - 0.069 13.6 0.2 0.069 13.6 0.2 3.5 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DivIC PF04977.15 OWF51955.1 - 0.31 10.8 9.2 2.3 8.0 0.6 3.8 3 0 0 3 3 3 0 Septum formation initiator Sucrose_synth PF00862.19 OWF51955.1 - 0.41 8.9 5.7 0.047 12.0 1.3 1.6 2 0 0 2 2 2 0 Sucrose synthase Leu_zip PF15294.6 OWF51955.1 - 1.9 7.9 23.1 4.4 6.7 3.1 3.2 2 1 1 3 3 3 0 Leucine zipper Baculo_PEP_C PF04513.12 OWF51955.1 - 5.2 7.1 6.0 11 6.0 0.6 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 OWF51955.1 - 9.7 6.9 13.7 5.9 7.6 0.0 4.1 4 1 1 5 5 5 0 SlyX Fibrinogen_BP PF08017.11 OWF51956.1 - 8.6e-16 57.3 22.7 1e-15 57.1 22.7 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein CEL_III_C PF18054.1 OWF51956.1 - 1.6e-06 28.2 1.7 0.062 13.4 0.1 2.5 1 1 2 3 3 3 3 CEL-III C-terminal SecD_SecF PF02355.16 OWF51956.1 - 2.4e-05 23.8 0.4 4.4 6.6 0.2 4.6 1 1 2 3 3 3 3 Protein export membrane protein DUF5314 PF17241.2 OWF51956.1 - 0.00044 20.0 1.5 1.3 8.6 1.0 3.4 1 1 1 2 2 2 1 Family of unknown function (DUF5314) Hairpins PF04877.12 OWF51956.1 - 0.0005 19.8 0.7 0.45 10.1 0.7 3.4 1 1 0 1 1 1 1 HrpZ HEPN_Swt1 PF18731.1 OWF51956.1 - 0.017 15.4 0.5 7.1 7.0 0.5 3.4 1 1 0 1 1 1 0 Swt1-like HEPN FAM75 PF14650.6 OWF51956.1 - 0.15 11.6 13.7 2.1 7.8 4.1 2.1 1 1 1 2 2 2 0 FAM75 family AAA_15 PF13175.6 OWF51956.1 - 0.45 10.2 13.3 61 3.2 13.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain SSPI PF14098.6 OWF51956.1 - 7.7 6.8 24.4 35 4.7 0.3 5.8 1 1 3 4 4 4 0 Small, acid-soluble spore protein I Fibrinogen_BP PF08017.11 OWF51957.1 - 3e-14 52.3 50.3 3.8e-14 51.9 50.3 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein CEL_III_C PF18054.1 OWF51957.1 - 6.4e-06 26.3 17.3 0.029 14.4 0.7 3.2 1 1 2 3 3 3 3 CEL-III C-terminal DUF445 PF04286.12 OWF51957.1 - 0.00085 19.2 36.6 0.049 13.4 14.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF445) DUF5314 PF17241.2 OWF51957.1 - 0.031 13.9 20.6 0.27 10.9 0.2 4.4 1 1 2 3 3 3 0 Family of unknown function (DUF5314) GerPC PF10737.9 OWF51957.1 - 0.15 12.1 25.6 0.022 14.8 6.0 3.5 1 1 2 3 3 3 0 Spore germination protein GerPC TagF_N PF09867.9 OWF51957.1 - 0.29 11.2 1.6 26 4.8 0.0 4.2 1 1 3 4 4 4 0 TagF N-terminal domain, Type VI secretion system-associated DUF45 PF01863.17 OWF51957.1 - 0.82 9.7 23.5 1.6 8.7 2.0 3.8 1 1 3 4 4 4 0 Protein of unknown function DUF45 RNase_J_C PF17770.1 OWF51957.1 - 1.7 9.8 24.4 12 7.0 0.9 5.1 1 1 5 6 6 6 0 Ribonuclease J C-terminal domain SecD_SecF PF02355.16 OWF51957.1 - 1.9 7.8 11.0 32 3.8 0.1 5.0 1 1 4 5 5 5 0 Protein export membrane protein DUF4918 PF16265.5 OWF51957.1 - 3.1 7.3 12.8 0.058 12.9 1.6 3.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4918) FAM75 PF14650.6 OWF51957.1 - 8.4 5.8 46.8 3.8 7.0 15.1 3.2 1 1 2 3 3 3 0 FAM75 family Fibrinogen_BP PF08017.11 OWF51958.1 - 2.7e-10 39.3 26.2 3.1e-10 39.1 26.2 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein CEL_III_C PF18054.1 OWF51958.1 - 0.00046 20.3 10.8 0.068 13.2 3.1 2.5 1 1 0 2 2 2 2 CEL-III C-terminal DUF5314 PF17241.2 OWF51958.1 - 0.0032 17.2 7.1 0.088 12.5 0.7 2.4 1 1 0 2 2 2 2 Family of unknown function (DUF5314) AAA_lid_6 PF17866.1 OWF51958.1 - 0.083 13.1 15.1 15 5.8 1.6 5.2 1 1 1 2 2 2 0 AAA lid domain DUF445 PF04286.12 OWF51958.1 - 0.18 11.6 19.7 0.3 10.9 19.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) GerPC PF10737.9 OWF51958.1 - 0.22 11.6 8.1 3 7.9 8.1 2.1 1 1 0 1 1 1 0 Spore germination protein GerPC FAM75 PF14650.6 OWF51958.1 - 0.41 10.1 28.2 0.84 9.1 13.8 2.1 1 1 1 2 2 2 0 FAM75 family WGG PF10273.9 OWF51958.1 - 0.55 10.9 7.0 7.5 7.3 0.3 3.8 2 2 1 3 3 3 0 Pre-rRNA-processing protein TSR2 RNase_J_C PF17770.1 OWF51958.1 - 0.83 10.7 14.0 11 7.2 0.6 3.5 1 1 3 4 4 4 0 Ribonuclease J C-terminal domain DUF2924 PF11149.8 OWF51958.1 - 1.3 9.4 8.0 1.4 9.3 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) AAA_lid_5 PF17865.1 OWF51958.1 - 1.4 9.1 5.4 5.1 7.2 0.3 2.9 1 1 1 3 3 3 0 Midasin AAA lid domain Tam41_Mmp37 PF09139.11 OWF51958.1 - 1.7 8.0 8.7 14 5.0 8.7 1.9 1 1 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial GTP_EFTU PF00009.27 OWF51959.1 - 2.3e-29 102.3 0.0 4e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OWF51959.1 - 5.9e-12 45.4 0.0 4e-11 42.8 0.0 2.3 1 1 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OWF51959.1 - 9e-06 25.6 0.0 5.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OWF51959.1 - 3.8e-05 24.0 0.6 0.00011 22.5 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PMP22_Claudin PF00822.20 OWF51960.1 - 2e-05 24.5 5.8 2.7e-05 24.1 5.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 OWF51960.1 - 0.36 11.0 11.8 0.017 15.3 6.4 1.4 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein PGF-CTERM PF18204.1 OWF51961.1 - 0.00075 19.4 0.0 0.0023 17.8 0.0 1.9 1 0 0 1 1 1 1 PGF-CTERM motif DUF4149 PF13664.6 OWF51961.1 - 0.11 12.8 6.1 2 8.7 4.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Sex_peptide PF08138.11 OWF51961.1 - 0.51 10.5 0.1 0.51 10.5 0.1 2.3 3 0 0 3 3 3 0 Sex peptide (SP) family Ndc1_Nup PF09531.10 OWF51961.1 - 2.4 6.8 5.7 3 6.4 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM43 PF07787.12 OWF51961.1 - 3.7 6.9 10.7 0.13 11.6 4.4 1.7 2 0 0 2 2 2 0 Transmembrane protein 43 Ependymin PF00811.18 OWF51962.1 - 5.3e-08 33.2 0.2 5.3e-07 29.9 0.0 2.1 1 1 1 2 2 2 1 Ependymin Ependymin PF00811.18 OWF51963.1 - 5e-09 36.5 0.4 1e-08 35.5 0.1 1.7 2 0 0 2 2 2 1 Ependymin TNFR_c6 PF00020.18 OWF51964.1 - 1.1e-05 25.8 5.4 1.9e-05 25.0 5.4 1.4 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region DUF5527 PF17665.1 OWF51964.1 - 0.0052 16.3 0.1 0.87 9.1 0.0 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5527) TMEM132D_C PF15706.5 OWF51964.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Chordopox_A13L PF05961.11 OWF51964.1 - 0.047 13.9 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF3951 PF13131.6 OWF51964.1 - 0.078 13.2 0.5 0.15 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) EphA2_TM PF14575.6 OWF51964.1 - 0.15 12.9 0.3 0.68 10.9 0.5 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TSC21 PF15217.6 OWF51966.1 - 0.022 14.7 0.1 9.3 6.2 0.1 2.3 2 0 0 2 2 2 0 TSC21 family HSP20 PF00011.21 OWF51967.1 - 5e-32 110.1 11.8 3.9e-17 62.3 0.2 3.0 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OWF51967.1 - 1.4e-07 31.0 0.2 0.0083 15.7 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA YabP PF07873.11 OWF51967.1 - 0.0098 15.7 0.4 0.82 9.5 0.0 3.1 3 0 0 3 3 3 1 YabP family Peptidase_S26 PF10502.9 OWF51968.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 FCH PF00611.23 OWF51969.1 - 1.4e-15 57.3 0.6 1.4e-15 57.3 0.6 3.4 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 OWF51969.1 - 1.4e-10 40.9 0.0 3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF51969.1 - 9.8e-10 37.9 0.0 9.8e-10 37.9 0.0 1.8 2 0 0 2 2 1 1 SH3 domain Atg14 PF10186.9 OWF51969.1 - 0.0043 16.2 5.7 0.0043 16.2 5.7 1.5 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF285 PF03382.14 OWF51969.1 - 0.033 14.0 2.3 0.34 10.7 0.1 2.7 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 EzrA PF06160.12 OWF51969.1 - 0.12 10.5 13.0 0.052 11.7 10.3 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 OWF51969.1 - 0.32 10.3 8.6 0.6 9.4 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SH3BP5 PF05276.14 OWF51969.1 - 0.68 9.7 17.0 0.23 11.2 0.9 3.4 1 1 2 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) SHE3 PF17078.5 OWF51969.1 - 2 8.0 18.2 0.05 13.3 6.9 2.9 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 TPR_MLP1_2 PF07926.12 OWF51969.1 - 2.3 8.3 16.4 4.3 7.4 12.2 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Med30 PF11315.8 OWF51969.1 - 3.1 8.0 8.5 0.71 10.1 2.1 2.9 2 1 1 3 3 3 0 Mediator complex subunit 30 OmpH PF03938.14 OWF51969.1 - 9.9 6.5 19.4 1.4 9.3 14.6 2.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Frag1 PF10277.9 OWF51970.1 - 2.2e-28 99.3 13.5 2.5e-28 99.1 13.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3859 PF12975.7 OWF51970.1 - 0.097 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Ank_2 PF12796.7 OWF51971.1 - 2.1e-23 82.7 7.6 8.4e-07 29.5 0.1 6.5 3 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF51971.1 - 4.9e-16 58.6 4.1 0.00085 19.6 0.1 8.4 6 1 3 9 9 9 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF51971.1 - 8.6e-14 51.7 0.5 0.17 12.5 0.0 7.7 7 1 0 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF51971.1 - 1.4e-13 49.7 4.9 1.4 9.7 0.0 9.4 10 0 0 10 10 8 3 Ankyrin repeat Ank PF00023.30 OWF51971.1 - 1.4e-05 25.3 0.7 5.5 7.6 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeat ABC_tran PF00005.27 OWF51971.1 - 0.028 14.9 0.1 0.13 12.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 OWF51971.1 - 0.053 13.5 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3450 PF11932.8 OWF51971.1 - 0.075 12.3 0.9 0.12 11.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Hormone_4 PF00220.17 OWF51971.1 - 0.12 12.4 1.5 0.55 10.3 1.5 2.2 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain AAA_22 PF13401.6 OWF51971.1 - 0.15 12.4 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 OWF51971.1 - 0.16 12.0 0.1 0.82 9.7 0.0 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1378 PF07125.11 OWF51971.1 - 0.45 10.7 1.7 93 3.3 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1378) DUF1664 PF07889.12 OWF51971.1 - 0.81 9.7 5.6 2.3 8.3 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TIR PF01582.20 OWF51973.1 - 3.8e-13 49.6 0.0 6.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF51973.1 - 8.9e-13 48.9 0.0 1.7e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain GAIN PF16489.5 OWF51974.1 - 3.5e-18 65.8 1.1 6.4e-18 65.0 1.1 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain 7tm_2 PF00002.24 OWF51974.1 - 2.3e-16 59.8 10.5 3.8e-16 59.1 10.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) fn3 PF00041.21 OWF51974.1 - 6e-12 45.7 4.2 0.00022 21.5 0.5 3.7 3 0 0 3 3 3 2 Fibronectin type III domain GPS PF01825.21 OWF51974.1 - 2e-10 41.1 4.6 5e-10 39.8 4.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Ig_3 PF13927.6 OWF51974.1 - 2.7e-10 40.7 0.3 1.3e-07 32.2 0.1 3.5 2 0 0 2 2 2 1 Immunoglobulin domain HRM PF02793.22 OWF51974.1 - 1.1e-08 35.2 0.6 2.2e-08 34.3 0.6 1.5 1 0 0 1 1 1 1 Hormone receptor domain V-set PF07686.17 OWF51974.1 - 5e-08 33.1 5.8 3.3e-05 24.0 0.2 4.4 3 1 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.25 OWF51974.1 - 3.5e-06 27.1 0.3 1.1e-05 25.5 0.3 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF51974.1 - 1.3e-05 25.1 0.1 9.7e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF51974.1 - 0.0012 19.1 2.1 0.013 15.8 0.1 3.0 3 0 0 3 3 2 1 Immunoglobulin domain Ig_6 PF18452.1 OWF51974.1 - 0.025 14.2 0.1 0.11 12.1 0.1 2.2 1 0 0 1 1 1 0 Immunoglobulin domain C1-set PF07654.15 OWF51974.1 - 0.16 12.4 1.5 0.53 10.7 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin C1-set domain 7tm_2 PF00002.24 OWF51975.1 - 2.4e-46 158.0 22.8 3.8e-46 157.4 22.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 OWF51975.1 - 4.6e-16 58.9 1.4 8e-16 58.1 1.4 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Ig_3 PF13927.6 OWF51975.1 - 1e-12 48.4 0.0 3e-06 27.7 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain GPS PF01825.21 OWF51975.1 - 3.6e-11 43.4 4.0 8.7e-11 42.2 4.0 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif I-set PF07679.16 OWF51975.1 - 1.1e-09 38.2 0.0 0.00025 21.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain HRM PF02793.22 OWF51975.1 - 6.9e-08 32.7 1.2 1.7e-07 31.4 1.2 1.7 1 0 0 1 1 1 1 Hormone receptor domain ig PF00047.25 OWF51975.1 - 8.2e-08 32.3 0.1 0.00049 20.2 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF51975.1 - 9.9e-08 32.2 0.1 5.8e-05 23.4 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 OWF51975.1 - 0.00014 22.0 2.1 2.4 8.4 0.6 4.7 3 2 0 3 3 3 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF51975.1 - 0.0027 17.7 0.1 0.1 12.6 0.1 2.7 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 OWF51975.1 - 0.17 11.5 0.6 0.59 9.7 0.0 2.2 3 0 0 3 3 3 0 Immunoglobulin domain PMG PF05287.12 OWF51976.1 - 1.4e-05 25.2 18.9 24 4.9 0.0 10.3 2 2 5 8 8 8 4 PMG protein 7tm_2 PF00002.24 OWF51977.1 - 4.3e-50 170.3 22.6 7e-50 169.6 22.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 OWF51977.1 - 3.1e-17 62.7 2.8 6.8e-17 61.6 2.8 1.5 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Ig_3 PF13927.6 OWF51977.1 - 1.3e-15 57.7 6.6 2.2e-09 37.8 0.1 4.2 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 OWF51977.1 - 3.7e-09 36.8 4.1 2.7e-06 27.6 1.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain GPS PF01825.21 OWF51977.1 - 1.5e-08 35.0 9.3 4.7e-08 33.4 9.3 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif I-set PF07679.16 OWF51977.1 - 2.2e-08 34.1 1.4 0.00093 19.2 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 OWF51977.1 - 1.9e-07 31.2 9.3 8.2e-05 22.7 0.6 3.5 4 0 0 4 4 4 2 Immunoglobulin domain HRM PF02793.22 OWF51977.1 - 1.2e-05 25.5 1.1 3e-05 24.2 1.1 1.6 1 0 0 1 1 1 1 Hormone receptor domain V-set PF07686.17 OWF51977.1 - 8.9e-05 22.6 5.7 0.65 10.2 2.4 4.0 3 1 0 3 3 3 2 Immunoglobulin V-set domain UPF0715 PF17094.5 OWF51977.1 - 0.0011 19.5 0.8 0.0011 19.5 0.8 2.7 2 1 0 2 2 1 1 Uncharacterised protein family (UPF0715) DUF4492 PF14899.6 OWF51977.1 - 0.052 13.5 0.3 0.16 11.9 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) DUF1772 PF08592.11 OWF51977.1 - 1.3 9.3 8.8 20 5.5 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Brix PF04427.18 OWF51978.1 - 7.8e-40 137.0 0.0 7.8e-40 137.0 0.0 1.8 2 1 0 2 2 2 1 Brix domain NUP50 PF08911.11 OWF51978.1 - 5.6 7.7 8.8 0.54 11.0 2.3 2.3 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) E2F_TDP PF02319.20 OWF51979.1 - 8.2e-43 144.3 0.9 1.5e-22 79.4 0.1 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 OWF51979.1 - 0.00044 20.1 0.1 0.0014 18.5 0.1 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB UPF0122 PF04297.14 OWF51979.1 - 0.2 11.9 0.9 6.9 7.0 0.1 2.6 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like UbiD PF01977.16 OWF51980.1 - 7.8e-14 51.3 5.3 0.16 10.8 0.2 7.9 2 2 4 6 6 6 6 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YebF PF13995.6 OWF51980.1 - 1.6e-05 24.8 0.0 42 4.3 0.0 7.2 2 2 8 11 11 11 0 YebF-like protein DotD PF16816.5 OWF51980.1 - 2.1e-05 24.5 2.3 61 3.6 0.0 7.0 2 2 5 8 8 8 0 DotD protein DUF2870 PF11069.8 OWF51980.1 - 0.0011 19.2 1.4 0.61 10.5 0.0 4.1 2 1 1 4 4 4 1 Protein of unknown function (DUF2870) GlnE PF03710.15 OWF51980.1 - 0.016 14.6 1.1 62 2.9 0.0 4.4 3 2 1 5 5 5 0 Glutamate-ammonia ligase adenylyltransferase PilJ PF13675.6 OWF51980.1 - 0.026 14.6 19.4 44 4.2 0.9 8.7 5 2 1 8 8 8 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4062 PF13271.6 OWF51981.1 - 7.9e-12 45.4 0.0 2.4e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) NACHT PF05729.12 OWF51981.1 - 2.7e-09 37.2 0.0 7.1e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OWF51981.1 - 2.5e-05 24.5 0.0 7.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OWF51981.1 - 0.00017 21.6 0.0 0.00055 19.9 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OWF51981.1 - 0.00019 20.7 0.0 0.00046 19.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OWF51981.1 - 0.00035 21.0 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 OWF51981.1 - 0.0092 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OWF51981.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OWF51981.1 - 0.1 12.7 0.0 0.66 10.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OWF51981.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 OWF51981.1 - 0.16 11.7 0.1 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein MANEC PF07502.14 OWF51982.1 - 1.9e-08 34.5 8.7 3.5e-08 33.6 8.7 1.4 1 0 0 1 1 1 1 MANEC domain PAN_3 PF08277.12 OWF51982.1 - 0.033 14.0 7.4 0.11 12.3 7.4 1.9 1 0 0 1 1 1 0 PAN-like domain Cadherin PF00028.17 OWF51983.1 - 2e-43 146.7 22.1 2.7e-11 43.7 0.2 7.9 7 1 0 7 7 7 6 Cadherin domain DUF1735 PF08522.10 OWF51983.1 - 0.06 13.9 0.3 0.06 13.9 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1735) Vpu PF00558.19 OWF51983.1 - 0.4 10.5 4.9 0.23 11.2 1.4 2.2 2 0 0 2 2 2 0 Vpu protein Glyco_hydro_2 PF00703.21 OWF51983.1 - 1.6 9.4 7.7 1.6 9.4 0.0 4.4 5 0 0 5 5 5 0 Glycosyl hydrolases family 2 CSD PF00313.22 OWF51984.1 - 2.5e-23 81.7 0.1 3.3e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 OWF51984.1 - 3.6e-07 29.9 12.1 0.00065 19.7 0.7 3.1 2 1 0 2 2 2 2 Zinc knuckle OB_RNB PF08206.11 OWF51984.1 - 0.00027 20.6 0.0 0.00053 19.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain eIF3g PF12353.8 OWF51984.1 - 0.0026 18.2 3.9 0.21 12.0 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 OWF51984.1 - 0.0042 16.9 1.0 0.014 15.2 1.0 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OWF51984.1 - 0.11 12.3 5.5 2.9 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 OWF51984.1 - 0.43 10.5 8.4 4.6 7.2 0.8 2.6 2 0 0 2 2 2 0 Zinc knuckle 7tm_2 PF00002.24 OWF51985.1 - 2.9e-51 174.2 19.6 4e-51 173.7 19.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 OWF51985.1 - 4.7e-15 55.9 4.8 8.8e-15 55.0 4.8 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Frizzled PF01534.17 OWF51985.1 - 1.7e-07 30.6 21.6 3.8e-05 22.9 21.7 2.4 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_1 PF00001.21 OWF51985.1 - 0.013 14.9 11.8 0.024 14.0 11.8 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) LTP_2 PF14368.6 OWF51985.1 - 0.098 12.8 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 Probable lipid transfer DUF4834 PF16118.5 OWF51985.1 - 3.9 8.5 5.3 9.5 7.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) UEV PF05743.13 OWF51987.1 - 2e-43 147.1 0.1 3.9e-43 146.2 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 OWF51987.1 - 1.8e-25 88.7 3.2 4.1e-25 87.5 0.6 2.3 2 0 0 2 2 2 1 Vps23 core domain SOG2 PF10428.9 OWF51987.1 - 0.014 14.7 1.9 0.016 14.4 1.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PTS_IIA PF02255.16 OWF51987.1 - 0.058 13.4 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit FapA PF03961.13 OWF51987.1 - 0.059 12.0 1.7 0.082 11.5 1.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5415 PF17436.2 OWF51987.1 - 0.061 13.4 0.3 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5415) PL48 PF15903.5 OWF51987.1 - 0.071 12.1 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 Prominin PF05478.11 OWF51987.1 - 0.11 10.5 2.0 0.14 10.1 2.0 1.1 1 0 0 1 1 1 0 Prominin Poly_export PF02563.16 OWF51987.1 - 0.16 12.2 0.3 2.8 8.2 0.0 3.1 3 1 0 3 3 3 0 Polysaccharide biosynthesis/export protein Spc24 PF08286.11 OWF51987.1 - 0.31 11.3 5.4 0.13 12.5 2.1 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3552 PF12072.8 OWF51987.1 - 3 7.2 8.9 4.8 6.6 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Abhydrolase_1 PF00561.20 OWF51988.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cpn60_TCP1 PF00118.24 OWF51989.1 - 2e-145 485.2 9.8 2.3e-145 485.0 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1104 PF06518.11 OWF51989.1 - 0.46 10.9 3.8 0.86 10.0 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) Anoct_dimer PF16178.5 OWF51990.1 - 7.1e-39 133.8 0.8 9.2e-39 133.5 0.8 1.1 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin BIR PF00653.21 OWF51992.1 - 3.4e-35 120.5 6.1 4.9e-18 65.5 0.2 2.8 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 OWF51992.1 - 0.00039 20.5 0.1 0.33 11.0 0.0 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like TMEM154 PF15102.6 OWF51994.1 - 0.014 15.3 2.3 0.033 14.1 2.3 1.8 1 0 0 1 1 1 0 TMEM154 protein family DUF908 PF06012.12 OWF51995.1 - 0.96 8.8 6.5 1.1 8.6 6.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Orthoreo_P10 PF07204.11 OWF51996.1 - 0.0051 16.7 0.1 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 OWF51996.1 - 0.012 16.5 0.0 0.047 14.6 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF51996.1 - 0.58 10.1 23.8 0.63 9.9 15.6 3.6 2 2 0 2 2 2 0 TMEM154 protein family CEP209_CC5 PF16574.5 OWF51997.1 - 5.7e-38 130.0 19.6 5.7e-38 130.0 19.6 20.1 12 7 8 21 21 21 2 Coiled-coil region of centrosome protein CE290 KASH_CCD PF14662.6 OWF51997.1 - 0.0016 18.3 13.3 0.0016 18.3 13.3 21.8 7 5 13 22 22 22 3 Coiled-coil region of CCDC155 or KASH Cytomega_TRL10 PF06084.11 OWF51998.1 - 0.057 13.4 0.2 0.057 13.4 0.2 2.0 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein IGFL PF14653.6 OWF51998.1 - 0.14 12.2 2.2 0.25 11.3 0.3 2.4 2 0 0 2 2 2 0 Insulin growth factor-like family DUF3953 PF13129.6 OWF51998.1 - 0.19 11.5 2.4 0.37 10.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) Trp_oprn_chp PF09534.10 OWF51998.1 - 0.19 11.5 0.1 0.57 10.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PAS_3 PF08447.12 OWF51999.1 - 1.7e-22 79.5 0.0 2.6e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 OWF51999.1 - 5.3e-15 55.5 0.3 3.7e-13 49.6 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OWF51999.1 - 1.2e-14 54.3 0.0 1.2e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 OWF51999.1 - 1.5e-06 28.0 0.2 2.9e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 OWF51999.1 - 0.00012 22.3 0.0 0.00085 19.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain UPAR_LY6 PF00021.21 OWF52000.1 - 4.4e-06 27.3 26.3 0.00013 22.6 10.7 4.6 5 1 0 5 5 5 2 u-PAR/Ly-6 domain TMEM154 PF15102.6 OWF52001.1 - 0.016 15.1 1.2 0.016 15.1 1.2 1.9 2 0 0 2 2 2 0 TMEM154 protein family Y_phosphatase PF00102.27 OWF52003.1 - 7.6e-120 398.8 0.0 1.4e-69 234.3 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF52003.1 - 1.3e-05 25.1 0.1 5.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF52003.1 - 0.00081 19.5 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF52003.1 - 0.0015 18.5 0.9 0.0061 16.6 0.0 2.3 2 1 1 3 3 3 1 Tyrosine phosphatase family Herpes_gE PF02480.16 OWF52003.1 - 0.0016 17.3 0.1 0.0027 16.5 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E CxC3 PF18804.1 OWF52003.1 - 0.094 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases F5_F8_type_C PF00754.25 OWF52004.1 - 0.0016 18.5 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PHD PF00628.29 OWF52005.1 - 5.1e-18 64.7 26.2 4.4e-11 42.5 10.3 2.9 1 1 1 2 2 2 2 PHD-finger SAM_1 PF00536.30 OWF52005.1 - 8e-13 48.6 0.2 6.6e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF52005.1 - 2.8e-08 33.7 0.0 7.8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Prok-RING_1 PF14446.6 OWF52005.1 - 0.0037 17.2 1.1 0.0037 17.2 1.1 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 OWF52005.1 - 0.004 17.0 19.5 0.011 15.7 1.5 2.8 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OWF52005.1 - 0.0072 15.9 1.7 0.0072 15.9 1.7 3.0 3 1 0 3 3 3 2 PHD-finger SAM_PNT PF02198.16 OWF52005.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Sua5_yciO_yrdC PF01300.18 OWF52005.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Telomere recombination ADK_lid PF05191.14 OWF52005.1 - 0.63 10.1 9.7 14 5.8 2.6 4.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid PHD PF00628.29 OWF52006.1 - 4e-17 61.8 23.0 9.2e-12 44.7 7.0 2.5 1 1 1 2 2 2 2 PHD-finger SAM_1 PF00536.30 OWF52006.1 - 8.3e-09 35.8 0.2 2.1e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF52006.1 - 1.3e-05 25.2 0.5 3.6e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 OWF52006.1 - 0.0023 17.8 17.7 0.055 13.4 2.9 2.6 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OWF52006.1 - 0.0024 17.4 2.3 0.0024 17.4 2.3 2.9 3 1 0 3 3 3 2 PHD-finger PHD_4 PF16866.5 OWF52006.1 - 0.0096 16.0 7.5 0.0096 16.0 7.5 3.0 1 1 1 2 2 2 1 PHD-finger SAM_PNT PF02198.16 OWF52006.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain C1_2 PF03107.16 OWF52006.1 - 1.6 9.1 23.7 0.2 12.0 2.7 2.9 3 0 0 3 3 3 0 C1 domain GDP_Man_Dehyd PF16363.5 OWF52008.1 - 3.5e-58 197.6 0.0 4.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OWF52008.1 - 1e-50 172.4 0.0 1.2e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OWF52008.1 - 1.1e-15 57.5 0.0 1.1e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OWF52008.1 - 1.1e-12 47.8 0.0 2.7e-11 43.2 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OWF52008.1 - 5.6e-11 42.1 0.0 8.5e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OWF52008.1 - 2.3e-08 34.2 0.0 3.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OWF52008.1 - 1.1e-07 31.3 0.0 1.3e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OWF52008.1 - 1.5e-07 31.5 0.2 4.3e-07 30.0 0.2 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OWF52008.1 - 9.8e-06 25.1 0.1 1.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 OWF52008.1 - 5.2e-05 22.9 0.2 0.0054 16.3 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family Rtf2 PF04641.12 OWF52009.1 - 2.6e-84 282.7 8.9 3.3e-84 282.3 8.9 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger PEPCK_N PF17297.2 OWF52009.1 - 0.0072 16.0 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain NuDC PF16273.5 OWF52009.1 - 0.015 15.8 5.5 0.015 15.8 5.5 2.7 3 0 0 3 3 3 0 Nuclear distribution C domain Hid1 PF12722.7 OWF52009.1 - 2.1 6.4 6.0 2.4 6.2 6.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 OWF52009.1 - 9 5.4 6.2 12 5.1 6.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mtp PF03821.16 OWF52010.1 - 3.6e-20 72.5 4.1 3.3e-10 40.0 0.2 2.2 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 OWF52010.1 - 0.0041 17.8 8.4 0.018 15.7 0.1 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4728) Arrestin_N PF00339.29 OWF52011.1 - 4.2e-28 98.2 0.0 8.1e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF52011.1 - 4.1e-19 69.4 0.0 1.9e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 OWF52011.1 - 0.0021 17.7 0.0 0.087 12.4 0.0 2.5 3 0 0 3 3 3 1 SpoOM protein Vps26 PF03643.15 OWF52011.1 - 0.036 13.1 0.6 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 OWF52011.1 - 0.042 13.0 0.9 28 3.7 0.2 3.8 4 0 0 4 4 4 0 Rgp1 DUF4572 PF15139.6 OWF52012.1 - 1.2e-71 240.6 4.5 1.4e-71 240.5 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) Laminin_EGF PF00053.24 OWF52013.1 - 7.7e-152 493.4 446.0 6.8e-10 38.9 13.4 23.1 22 1 1 23 23 23 22 Laminin EGF domain Laminin_G_2 PF02210.24 OWF52013.1 - 5.5e-111 366.3 0.0 4.7e-26 91.8 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 OWF52013.1 - 5.8e-105 346.8 0.0 4e-25 88.5 0.0 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 OWF52013.1 - 3.7e-78 262.3 0.0 3.7e-78 262.3 0.0 2.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 OWF52013.1 - 2.1e-28 98.9 0.0 4.5e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.6 OWF52013.1 - 3.6e-14 53.2 1.0 0.017 15.2 0.0 5.4 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily Laminin_II PF06009.12 OWF52013.1 - 1.5e-13 50.9 4.2 1.5e-13 50.9 4.2 4.4 2 2 1 5 5 5 1 Laminin Domain II PI3K_P85_iSH2 PF16454.5 OWF52014.1 - 8.8e-35 119.7 20.4 1.7e-34 118.7 20.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 OWF52014.1 - 3.5e-33 113.5 0.1 2.6e-20 72.3 0.0 2.9 3 0 0 3 3 2 2 SH2 domain RhoGAP PF00620.27 OWF52014.1 - 1.1e-24 87.0 0.2 5.1e-24 84.8 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 OWF52014.1 - 1.5e-09 37.6 8.9 3.8e-09 36.3 8.9 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SKA2 PF16740.5 OWF52014.1 - 0.013 15.3 4.6 0.013 15.3 4.6 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 HALZ PF02183.18 OWF52014.1 - 0.039 14.2 0.9 0.039 14.2 0.9 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper Caps_synth_GfcC PF06251.11 OWF52014.1 - 0.21 11.2 1.4 0.34 10.5 1.4 1.4 1 0 0 1 1 1 0 Capsule biosynthesis GfcC BLOC1_2 PF10046.9 OWF52014.1 - 0.29 11.4 13.7 0.13 12.5 4.6 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT1_C PF12205.8 OWF52014.1 - 0.45 10.6 6.0 0.71 10.0 2.0 2.8 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Latarcin PF10279.9 OWF52014.1 - 0.61 10.5 3.4 2.1 8.8 3.4 2.1 1 1 0 1 1 1 0 Latarcin precursor PHD PF00628.29 OWF52014.1 - 0.67 9.9 7.3 2 8.4 7.3 1.8 1 0 0 1 1 1 0 PHD-finger Troponin PF00992.20 OWF52014.1 - 1.3 9.3 17.4 0.091 13.1 8.7 2.4 1 1 1 2 2 2 0 Troponin HAUS6_N PF14661.6 OWF52014.1 - 6.5 6.3 12.1 14 5.2 12.0 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Mod_r PF07200.13 OWF52014.1 - 7 6.8 23.6 1.6 8.8 5.8 3.3 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 OWF52014.1 - 8.4 5.9 8.3 14 5.1 8.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 OWF52014.1 - 8.6 5.6 12.5 0.71 9.1 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SH3_9 PF14604.6 OWF52015.1 - 1.7e-08 34.2 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF52015.1 - 0.0001 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF52015.1 - 0.00079 19.0 0.4 0.0019 17.7 0.4 1.6 1 1 0 1 1 1 1 SH3 domain 3HCDH_N PF02737.18 OWF52016.1 - 9.1e-54 182.1 2.4 1e-53 181.9 0.8 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 OWF52016.1 - 7.5e-43 146.7 0.1 1.2e-42 145.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 OWF52016.1 - 8.7e-31 106.4 0.0 3.6e-24 85.2 0.0 3.1 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 OWF52016.1 - 9.1e-24 84.6 0.1 1.5e-23 83.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1203 PF06718.11 OWF52016.1 - 0.18 12.1 0.1 0.66 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) Thiolase_N PF00108.23 OWF52017.1 - 2.2e-77 260.0 0.4 3.3e-77 259.4 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OWF52017.1 - 1.2e-46 157.4 0.0 2.5e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OWF52017.1 - 6e-07 29.3 0.2 1.5e-06 28.0 0.2 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 OWF52017.1 - 0.0092 14.7 0.2 0.02 13.6 0.2 1.5 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) AAA PF00004.29 OWF52018.1 - 6.5e-45 152.8 0.0 2.5e-41 141.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 OWF52018.1 - 3.1e-20 72.0 0.2 7.2e-20 70.9 0.2 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 OWF52018.1 - 1.6e-11 43.8 0.4 5.2e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OWF52018.1 - 5e-05 23.7 0.0 0.00036 21.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OWF52018.1 - 6.8e-05 23.0 0.0 0.00027 21.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OWF52018.1 - 0.00032 20.5 0.0 0.00092 19.0 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 OWF52018.1 - 0.01 16.4 0.6 0.068 13.7 0.0 2.8 3 0 0 3 3 1 0 AAA domain AAA_22 PF13401.6 OWF52018.1 - 0.011 16.0 4.5 0.12 12.6 0.0 3.8 3 1 1 4 4 4 0 AAA domain RNA_helicase PF00910.22 OWF52018.1 - 0.025 15.0 0.0 0.071 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 OWF52018.1 - 0.025 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OWF52018.1 - 0.037 13.5 0.0 0.66 9.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 OWF52018.1 - 0.039 13.7 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF52018.1 - 0.042 13.8 0.0 0.26 11.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OWF52018.1 - 0.07 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OWF52018.1 - 0.1 12.0 0.1 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OWF52018.1 - 0.11 12.7 0.0 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PAN_1 PF00024.26 OWF52019.1 - 3.9e-30 103.6 28.6 5.9e-10 39.0 5.8 4.4 4 0 0 4 4 4 4 PAN domain BRICHOS PF04089.14 OWF52019.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 BRICHOS domain TMEM51 PF15345.6 OWF52019.1 - 0.089 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 TUDOR PF00567.24 OWF52020.1 - 0 1026.2 23.6 1e-34 119.2 0.2 13.6 13 0 0 13 13 13 13 Tudor domain DUF4537 PF15057.6 OWF52020.1 - 3.2e-21 75.6 0.3 0.11 12.5 0.0 10.9 11 0 0 11 11 11 6 Domain of unknown function (DUF4537) Agenet PF05641.12 OWF52020.1 - 7.3e-21 74.4 16.7 0.18 12.3 0.0 12.0 11 0 0 11 11 11 6 Agenet domain SAWADEE PF16719.5 OWF52020.1 - 4.2e-11 43.0 18.9 0.43 10.6 0.0 11.4 12 0 0 12 12 12 4 SAWADEE domain DUF1325 PF07039.11 OWF52020.1 - 1.1e-10 41.8 3.4 0.046 13.8 0.0 8.6 10 0 0 10 10 10 2 SGF29 tudor-like domain Tudor_4 PF18358.1 OWF52020.1 - 0.18 11.4 4.4 14 5.4 0.0 5.3 5 0 0 5 5 5 0 Histone methyltransferase Tudor domain Tetraspanin PF00335.20 OWF52021.1 - 5.9e-44 150.5 6.7 6.7e-44 150.3 6.7 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 OWF52021.1 - 3.7 7.9 16.9 4.9 7.5 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) SURF2 PF05477.11 OWF52022.1 - 1.7e-36 126.1 22.4 9.4e-36 123.7 22.4 2.0 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 OWF52022.1 - 0.36 9.0 11.2 0.48 8.6 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family UCH PF00443.29 OWF52023.1 - 2.6e-61 207.4 0.0 9.1e-60 202.3 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF52023.1 - 2.4e-17 63.5 3.7 2.4e-17 63.5 3.7 5.2 3 2 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OWF52023.1 - 1.2e-15 57.5 6.5 1.2e-15 57.5 6.5 3.4 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein DUSP PF06337.12 OWF52023.1 - 2.3e-15 56.9 6.9 1.2e-11 45.1 0.1 3.8 3 1 0 3 3 3 2 DUSP domain DUF4005 PF13178.6 OWF52023.1 - 0.021 15.5 3.7 0.021 15.5 3.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4005) RsfS PF02410.15 OWF52025.1 - 6.9e-22 77.8 0.2 1.5e-21 76.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SNARE_assoc PF09335.11 OWF52026.1 - 1.7e-17 64.0 7.9 2.4e-17 63.5 6.8 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein ATP-grasp_4 PF13535.6 OWF52029.1 - 3.8e-08 33.1 0.0 1.3e-07 31.4 0.0 1.9 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 OWF52029.1 - 5e-08 32.8 0.0 2.6e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_N PF18130.1 OWF52029.1 - 7.4e-07 29.6 0.0 2.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_3 PF02655.14 OWF52029.1 - 0.00053 20.1 0.0 0.0076 16.3 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 OWF52029.1 - 0.00066 19.2 0.0 0.0016 17.9 0.0 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 OWF52029.1 - 0.0056 16.3 0.0 0.022 14.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OWF52029.1 - 0.021 14.4 0.0 0.11 12.0 0.0 2.2 2 1 0 2 2 2 0 RimK-like ATP-grasp domain DUF4489 PF14879.6 OWF52030.1 - 0.063 13.4 7.0 5.2 7.2 0.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4489) MRP-S22 PF10245.9 OWF52030.1 - 0.25 11.1 0.0 32 4.1 0.0 2.6 1 1 2 3 3 3 0 Mitochondrial 28S ribosomal protein S22 Cohesin_HEAT PF12765.7 OWF52030.1 - 0.6 10.5 16.7 36 4.8 0.2 6.6 2 2 7 9 9 9 0 HEAT repeat associated with sister chromatid cohesion Neur_chan_LBD PF02931.23 OWF52031.1 - 8.9e-47 159.3 0.7 1.2e-46 158.8 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52031.1 - 2.8e-16 60.3 17.2 4.2e-14 53.2 10.4 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HAP PF03866.13 OWF52031.1 - 0.025 14.6 1.5 0.05 13.6 1.5 1.4 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) Furin-like PF00757.20 OWF52032.1 - 1.8e-16 60.3 168.7 0.0016 18.3 16.5 13.6 1 1 9 11 11 11 10 Furin-like cysteine rich region Furin-like_2 PF15913.5 OWF52032.1 - 0.00094 19.3 8.6 0.00094 19.3 8.6 13.9 2 1 9 13 13 13 4 Furin-like repeat, cysteine-rich NNMT_PNMT_TEMT PF01234.17 OWF52033.1 - 2.2e-51 174.5 0.1 3.1e-51 174.0 0.1 1.1 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 OWF52033.1 - 1.3e-05 25.7 0.0 0.00012 22.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF52033.1 - 1.6e-05 24.8 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF52033.1 - 1.9e-05 25.3 0.0 0.0069 17.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF52033.1 - 0.00014 21.7 0.0 0.0022 17.8 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF52033.1 - 0.00051 20.7 0.0 0.0023 18.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain N2227 PF07942.12 OWF52033.1 - 0.00096 18.4 0.2 0.0016 17.7 0.2 1.3 1 0 0 1 1 1 1 N2227-like protein Pox_MCEL PF03291.16 OWF52033.1 - 0.0035 16.5 2.8 0.011 14.9 0.0 2.6 2 1 1 3 3 3 1 mRNA capping enzyme NNMT_PNMT_TEMT PF01234.17 OWF52034.1 - 1.8e-51 174.8 0.1 1.9e-51 174.7 0.1 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 OWF52034.1 - 4.6e-06 27.2 0.0 5.8e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF52034.1 - 6.4e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF52034.1 - 1.8e-05 25.4 0.0 0.016 15.9 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 OWF52034.1 - 0.00027 20.8 0.0 0.0052 16.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF52034.1 - 0.0011 19.7 0.0 0.0033 18.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 OWF52034.1 - 0.0061 15.8 0.1 0.0083 15.3 0.1 1.2 1 0 0 1 1 1 1 N2227-like protein Pox_MCEL PF03291.16 OWF52034.1 - 0.0083 15.3 0.0 0.019 14.1 0.1 1.6 1 1 0 1 1 1 1 mRNA capping enzyme DUF5524 PF17662.1 OWF52036.1 - 2.6e-24 86.1 11.6 3.1e-23 82.6 10.9 2.3 1 1 0 1 1 1 1 Family of unknown function (DUF5524) HJURP_mid PF12346.8 OWF52036.1 - 0.023 15.1 0.9 0.082 13.4 0.9 1.9 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat TRIQK PF15168.6 OWF52036.1 - 0.84 9.6 3.1 1.3 9.0 0.4 2.3 1 1 1 2 2 2 0 Triple QxxK/R motif-containing protein family Methyltransf_16 PF10294.9 OWF52037.1 - 2.3e-38 131.7 1.5 2.9e-38 131.3 1.5 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OWF52037.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OWF52037.1 - 7.7e-05 22.5 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF52037.1 - 0.00014 21.4 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OWF52037.1 - 0.00073 19.3 0.0 0.00097 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 OWF52037.1 - 0.0035 18.0 0.0 0.0064 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF52037.1 - 0.0049 16.7 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain SBP_bac_5 PF00496.22 OWF52037.1 - 0.19 10.7 0.4 0.74 8.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle 7tm_1 PF00001.21 OWF52040.1 - 2.2e-38 132.1 13.3 2.7e-38 131.8 13.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ESSS PF10183.9 OWF52041.1 - 0.022 15.0 0.1 0.028 14.6 0.1 1.1 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AvrPtoB-E3_ubiq PF09046.10 OWF52042.1 - 3.4 7.9 18.4 1.4e+02 2.7 0.0 7.5 1 1 7 8 8 8 0 AvrPtoB E3 ubiquitin ligase MFS_1 PF07690.16 OWF52043.1 - 4e-37 128.0 37.5 1.1e-27 96.9 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 OWF52043.1 - 1.8e-09 36.8 2.3 4.6e-09 35.4 2.3 1.7 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 OWF52043.1 - 1.1e-05 24.5 11.1 7.5e-05 21.8 1.0 2.7 1 1 1 2 2 2 2 MFS_1 like family RCR PF12273.8 OWF52045.1 - 0.0011 19.6 1.2 0.0041 17.8 1.2 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM132D_C PF15706.5 OWF52045.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Mid2 PF04478.12 OWF52045.1 - 0.035 14.0 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Meckelin PF09773.9 OWF52045.1 - 0.22 9.6 0.1 0.28 9.2 0.1 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Lipocalin_2 PF08212.12 OWF52046.1 - 4.8e-05 23.3 16.3 0.3 11.0 0.5 4.6 1 1 3 4 4 4 3 Lipocalin-like domain DUF2439 PF10382.9 OWF52046.1 - 0.00036 20.8 8.2 0.93 9.9 0.3 4.1 1 1 3 4 4 4 2 Protein of unknown function (DUF2439) MSG PF02349.15 OWF52046.1 - 0.0028 17.8 24.2 0.56 10.4 5.5 4.1 3 2 0 3 3 3 3 Major surface glycoprotein Multi_ubiq PF14452.6 OWF52046.1 - 0.0094 16.2 1.8 12 6.3 0.0 4.6 5 1 1 6 6 6 1 Multiubiquitin Nup54 PF13874.6 OWF52046.1 - 0.031 14.4 1.4 3.2 7.9 0.3 2.9 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Glyco_hyd_101C PF17451.2 OWF52046.1 - 0.032 14.5 4.4 67 3.8 4.4 4.1 1 1 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain Vac_Fusion PF02346.16 OWF52046.1 - 0.039 13.6 26.0 4.7 6.9 1.7 5.8 1 1 6 8 8 8 0 Chordopoxvirus multifunctional envelope protein A27 BLOC1_2 PF10046.9 OWF52046.1 - 0.045 14.1 0.9 12 6.2 0.1 3.0 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.20 OWF52046.1 - 0.12 11.8 15.7 0.017 14.5 9.2 2.0 1 1 1 2 2 2 0 Tropomyosin Prefoldin_2 PF01920.20 OWF52046.1 - 1.7 8.6 6.5 3.1 7.8 0.3 2.9 3 0 0 3 3 3 0 Prefoldin subunit XhlA PF10779.9 OWF52046.1 - 3.1 8.0 8.6 22 5.4 0.4 3.5 3 1 1 4 4 4 0 Haemolysin XhlA Paramecium_SA PF01508.16 OWF52046.1 - 8.4 6.9 20.2 17 6.0 6.0 4.2 1 1 1 2 2 2 0 Paramecium surface antigen domain Lipase_GDSL_2 PF13472.6 OWF52047.1 - 0.085 13.2 0.0 0.091 13.1 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Bac_surface_Ag PF01103.23 OWF52048.1 - 7.9e-49 166.9 0.2 9.5e-49 166.6 0.2 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 OWF52048.1 - 0.01 16.4 0.1 0.021 15.4 0.1 1.5 1 0 0 1 1 1 0 Surface antigen variable number repeat ShlB PF03865.13 OWF52048.1 - 0.012 15.0 0.2 2.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB zf-RING_UBOX PF13445.6 OWF52049.1 - 2.4e-10 40.2 7.0 2.4e-10 40.2 7.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF52049.1 - 1.1e-08 35.1 11.7 2.1e-08 34.2 11.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF52049.1 - 2.1e-08 34.3 9.5 2.1e-08 34.3 9.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OWF52049.1 - 2.1e-07 30.7 9.5 2.1e-07 30.7 9.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF52049.1 - 4.8e-07 29.5 6.4 4.8e-07 29.5 6.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF52049.1 - 1.9e-06 27.7 7.0 1.9e-06 27.7 7.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF52049.1 - 1.4e-05 24.9 12.4 1.4e-05 24.9 12.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF52049.1 - 0.0042 16.9 9.0 0.0042 16.9 9.0 2.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OWF52049.1 - 1.6 8.7 6.5 4.9 7.1 6.5 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2_6 PF13912.6 OWF52049.1 - 3.3 7.8 11.7 20 5.4 0.5 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-RING_11 PF17123.5 OWF52049.1 - 4.1 7.2 10.9 0.89 9.4 6.7 2.1 2 1 0 2 2 2 0 RING-like zinc finger NHL PF01436.21 OWF52050.1 - 6.9e-07 29.0 13.1 7.7e-05 22.5 0.0 5.4 6 0 0 6 6 6 1 NHL repeat SGL PF08450.12 OWF52050.1 - 4.4e-06 26.4 0.2 0.011 15.3 0.1 3.4 1 1 3 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OWF52050.1 - 7.5e-05 22.6 0.3 0.00016 21.6 0.3 1.5 1 0 0 1 1 1 1 Beta-propeller repeat PQQ_2 PF13360.6 OWF52050.1 - 0.03 13.9 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain DUF3053 PF11254.8 OWF52050.1 - 0.03 13.9 0.6 0.051 13.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) GAPES3 PF17154.4 OWF52050.1 - 0.044 13.8 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain T3SchapCesA PF11439.8 OWF52050.1 - 0.055 13.6 0.6 12 6.1 0.0 2.7 2 1 0 2 2 2 0 Type III secretion system filament chaperone CesA DUF2652 PF10851.8 OWF52050.1 - 0.068 13.3 0.9 0.17 12.0 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2652) Exonuc_VII_L PF02601.15 OWF52050.1 - 0.19 11.3 2.7 0.29 10.7 2.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit VWA PF00092.28 OWF52051.1 - 1.1e-08 35.6 0.0 1.8e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain SH3_1 PF00018.28 OWF52052.1 - 6.3e-16 57.7 0.2 1.7e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OWF52052.1 - 4.5e-11 42.4 0.0 9.4e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF52052.1 - 4.4e-10 39.1 2.3 6.4e-10 38.6 0.0 2.6 2 1 0 2 2 2 1 Variant SH3 domain PcF PF09461.10 OWF52052.1 - 0.48 10.8 2.4 1.5 9.2 2.4 1.9 1 0 0 1 1 1 0 Phytotoxin PcF protein WD40 PF00400.32 OWF52053.1 - 1.2e-13 51.3 9.0 0.00069 20.4 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 OWF52053.1 - 1.7e-12 47.6 0.1 0.036 13.9 0.0 4.9 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OWF52053.1 - 8.1e-12 45.3 1.2 0.00057 20.1 0.0 5.7 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 OWF52053.1 - 0.0058 15.4 0.6 13 4.5 0.0 4.4 5 0 0 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.12 OWF52053.1 - 0.0062 14.6 2.0 2.1 6.2 0.1 3.6 2 2 0 3 3 3 2 IKI3 family P53 PF00870.18 OWF52054.1 - 1.5e-66 223.9 0.3 2.7e-66 223.1 0.3 1.4 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.11 OWF52054.1 - 7.8e-18 63.5 0.1 1.7e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.17 OWF52054.1 - 1.3e-10 41.2 0.2 2.8e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF52054.1 - 2.5e-09 37.4 0.3 5.3e-09 36.4 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) P53_TAD PF08563.11 OWF52054.1 - 5.6e-09 35.3 0.2 1.4e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 P53 transactivation motif Voltage_CLC PF00654.20 OWF52055.1 - 2.9e-82 276.8 25.2 2.9e-82 276.8 25.2 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel ABC_trans_CmpB PF06541.11 OWF52055.1 - 0.32 11.2 10.9 0.029 14.6 4.7 2.4 2 0 0 2 2 2 0 Putative ABC-transporter type IV Phage_holin_3_1 PF05106.12 OWF52055.1 - 7 7.2 6.1 32 5.1 0.0 4.1 3 1 1 4 4 4 0 Phage holin family (Lysis protein S) BTP PF05232.12 OWF52056.1 - 0.078 13.1 0.7 0.078 13.1 0.7 2.8 3 1 0 3 3 3 0 Chlorhexidine efflux transporter DUF1772 PF08592.11 OWF52056.1 - 0.52 10.6 9.3 4.1 7.7 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF872 PF05915.12 OWF52056.1 - 0.84 9.8 7.2 1.2 9.3 6.1 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) PHO4 PF01384.20 OWF52056.1 - 2.1 7.3 4.9 2.8 6.9 4.9 1.3 1 0 0 1 1 1 0 Phosphate transporter family ABC2_membrane_3 PF12698.7 OWF52056.1 - 6.4 5.8 18.8 9.5 5.2 18.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CSD PF00313.22 OWF52057.1 - 9.1e-28 95.9 0.8 1.5e-27 95.2 0.8 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OWF52057.1 - 0.0012 18.5 0.3 0.007 16.0 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain SRCR PF00530.18 OWF52058.1 - 3.4e-79 261.7 20.1 3.1e-31 107.8 3.2 3.4 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF52058.1 - 1e-16 61.2 15.4 3.5e-05 24.3 0.1 3.9 4 1 0 4 4 4 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF52058.1 - 1.4e-09 38.4 1.5 0.037 14.5 0.3 3.5 3 0 0 3 3 3 3 Hepsin, SRCR domain DUF3439 PF11921.8 OWF52058.1 - 0.016 15.1 12.4 0.86 9.6 8.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) REGB_T4 PF10715.9 OWF52058.1 - 0.24 11.6 0.0 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 T4-page Endoribonuclease RegB SNF PF00209.18 OWF52059.1 - 5.5e-187 622.6 32.0 6.3e-187 622.4 32.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Glyco_tran_10_N PF17039.5 OWF52059.1 - 0.021 15.3 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal Glyco_hydro_31 PF01055.26 OWF52060.1 - 3.9e-55 187.8 0.9 6.3e-55 187.1 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 OWF52060.1 - 0.00026 20.1 1.3 0.0004 19.4 1.3 1.3 1 0 0 1 1 1 1 Melibiase FixS PF03597.15 OWF52060.1 - 5.3 6.8 6.7 18 5.1 5.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type PP2C PF00481.21 OWF52061.1 - 6.9e-59 199.6 0.1 9.2e-59 199.2 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OWF52061.1 - 6.7e-05 22.6 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C LPMO_10 PF03067.15 OWF52062.1 - 4e-29 102.6 1.3 6.5e-29 102.0 1.3 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading 7TM_GPCR_Srw PF10324.9 OWF52063.1 - 1.8e-25 89.9 19.8 2.8e-25 89.3 19.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF52063.1 - 1.9e-10 40.5 11.0 3.8e-10 39.5 11.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.6 OWF52064.1 - 0.02 15.7 0.0 0.064 14.1 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF52064.1 - 0.096 12.6 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF812 PF05667.11 OWF52065.1 - 0.0053 15.7 5.4 0.0053 15.7 5.4 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF812) Ion_trans PF00520.31 OWF52066.1 - 2.1e-27 95.9 27.4 6.5e-27 94.3 27.8 1.6 1 1 1 2 2 2 1 Ion transport protein BTB_2 PF02214.22 OWF52066.1 - 2.3e-18 66.3 0.1 7.5e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF52066.1 - 2.8e-11 43.2 10.9 2.8e-11 43.2 10.9 2.7 3 0 0 3 3 3 1 Ion channel Beta-Casp PF10996.8 OWF52067.1 - 9.1e-26 90.3 0.0 3.2e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OWF52067.1 - 5.1e-25 88.0 0.1 1.5e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OWF52067.1 - 9.4e-17 60.7 0.0 2.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OWF52067.1 - 1e-11 45.3 0.1 1.4e-10 41.5 0.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OWF52067.1 - 3.6e-10 39.7 0.4 3.5e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OWF52067.1 - 8.4e-07 29.0 0.0 3.4e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 OWF52067.1 - 2.1e-05 23.9 0.1 7.6e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Putative beta-lactamase-like family PhyH PF05721.13 OWF52068.1 - 1.4e-06 28.7 0.2 1.1e-05 25.8 0.2 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TPR_2 PF07719.17 OWF52068.1 - 0.13 12.5 0.0 25 5.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Scramblase PF03803.15 OWF52069.1 - 3.9e-47 160.4 0.1 4.5e-47 160.2 0.1 1.0 1 0 0 1 1 1 1 Scramblase AIP3 PF03915.13 OWF52070.1 - 2.8e-12 46.5 23.9 6.4e-12 45.3 16.1 2.2 2 0 0 2 2 2 2 Actin interacting protein 3 zf-B_box PF00643.24 OWF52070.1 - 2.5e-07 30.7 6.5 2.5e-07 30.7 6.5 3.9 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4 PF00097.25 OWF52070.1 - 5.9e-05 22.9 6.8 5.9e-05 22.9 6.8 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF52070.1 - 0.00012 22.0 3.4 0.00012 22.0 3.4 2.4 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF52070.1 - 0.00019 21.2 9.0 0.00019 21.2 9.0 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF52070.1 - 0.0004 20.2 6.3 0.0004 20.2 6.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF52070.1 - 0.00051 19.9 8.1 0.00051 19.9 8.1 3.7 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF52070.1 - 0.0045 16.8 6.4 0.0045 16.8 6.4 3.3 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 Ntox28 PF15605.6 OWF52070.1 - 0.0063 16.7 0.7 0.0063 16.7 0.7 3.3 4 1 1 5 5 4 1 Bacterial toxin 28 CEBP_ZZ PF16366.5 OWF52070.1 - 0.012 15.8 6.1 0.012 15.8 6.1 3.0 3 0 0 3 3 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF4715 PF15835.5 OWF52070.1 - 0.076 13.1 8.7 0.015 15.4 3.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4715) DUF1664 PF07889.12 OWF52070.1 - 0.19 11.7 19.7 0.064 13.3 4.5 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) OmpH PF03938.14 OWF52070.1 - 1.1 9.6 21.0 0.14 12.5 8.2 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 OWF52070.1 - 4.3 6.8 19.7 1.6 8.2 10.2 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit WXG100 PF06013.12 OWF52070.1 - 5.3 7.3 11.0 0.36 11.1 2.6 3.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG zf-C2H2_4 PF13894.6 OWF52071.1 - 8.3e-18 63.6 89.4 0.024 15.4 2.0 12.3 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF52071.1 - 5.8e-16 58.0 85.1 0.011 16.1 1.6 11.7 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 OWF52071.1 - 2.6e-05 24.9 51.9 0.0015 19.2 10.8 8.4 6 2 2 8 8 8 4 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 OWF52071.1 - 0.0019 18.2 1.4 0.0019 18.2 1.4 10.3 11 1 1 12 12 12 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF52071.1 - 0.0023 18.2 0.4 0.0023 18.2 0.4 9.2 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OWF52071.1 - 6.9 7.0 44.0 5.9 7.2 9.4 7.9 5 3 4 9 9 9 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 OWF52071.1 - 7.4 6.3 30.1 1.3 8.7 0.0 8.1 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger Reprolysin PF01421.19 OWF52072.1 - 2e-20 73.6 0.1 8.4e-20 71.5 0.1 1.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 OWF52072.1 - 9.7e-12 45.4 1.0 1.5e-11 44.8 1.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF52072.1 - 2.2e-10 41.1 0.1 4.6e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF52072.1 - 6.7e-10 39.2 0.1 1.1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 OWF52072.1 - 1.2e-09 38.6 2.0 2.4e-09 37.6 2.0 1.5 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin_4 PF13583.6 OWF52072.1 - 5e-09 36.1 2.3 1.1e-07 31.7 1.2 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF52072.1 - 0.00078 19.3 0.1 0.0019 18.1 0.1 1.6 1 0 0 1 1 1 1 Matrixin Pep_M12B_propep PF01562.19 OWF52072.1 - 0.11 12.7 0.0 0.73 10.1 0.0 2.2 1 1 0 1 1 1 0 Reprolysin family propeptide Cyclase PF04199.13 OWF52073.1 - 2e-35 122.0 0.1 2.4e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 OWF52074.1 - 8.5e-37 126.4 0.1 1.1e-36 126.1 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase UbiA PF01040.18 OWF52075.1 - 5.8e-35 120.8 11.6 7.3e-35 120.5 11.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAT PF02259.23 OWF52076.1 - 1.6e-117 392.7 9.9 1.6e-117 392.6 3.8 2.6 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OWF52076.1 - 2.4e-74 250.3 0.2 2.4e-74 250.3 0.2 2.5 3 0 0 3 3 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OWF52076.1 - 8.5e-62 207.8 10.2 2.5e-56 190.0 0.7 5.3 3 1 0 4 4 4 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OWF52076.1 - 3e-44 149.4 0.2 3e-44 149.4 0.2 4.3 4 1 1 5 5 5 1 FKBP12-rapamycin binding domain FATC PF02260.20 OWF52076.1 - 2.7e-16 59.1 2.5 6.3e-16 57.9 0.5 2.5 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.6 OWF52076.1 - 1.9e-14 53.8 19.0 8.5e-05 23.0 0.1 11.0 11 1 1 12 12 10 3 HEAT-like repeat HEAT_2 PF13646.6 OWF52076.1 - 1e-11 45.0 11.2 0.0041 17.5 0.0 9.6 7 3 5 12 12 12 5 HEAT repeats Sec7_N PF12783.7 OWF52076.1 - 5.1e-08 33.0 3.3 0.0056 16.6 0.0 5.3 4 1 1 5 5 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 OWF52076.1 - 1.2e-07 31.4 19.4 0.00039 20.4 0.0 11.4 14 0 0 14 14 12 1 HEAT repeat IFRD PF05004.13 OWF52076.1 - 2.8e-07 30.0 6.5 0.0011 18.2 0.0 5.7 4 2 2 6 6 6 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 OWF52076.1 - 5.5e-06 26.9 11.1 1.7 9.3 0.2 8.3 7 2 2 9 9 9 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OWF52076.1 - 0.00041 20.4 2.8 0.84 9.7 0.2 5.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 OWF52076.1 - 0.0092 16.2 0.1 1.8 8.8 0.0 3.8 3 1 1 4 4 3 1 Rapamycin-insensitive companion of mTOR, domain 5 UME PF08064.13 OWF52076.1 - 0.19 11.7 16.8 16 5.4 0.0 7.6 8 1 1 9 9 9 0 UME (NUC010) domain TPR_19 PF14559.6 OWF52076.1 - 0.51 10.9 4.7 1.1 9.8 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CLASP_N PF12348.8 OWF52076.1 - 2.8 7.4 12.0 6.7 6.2 0.0 6.0 6 0 0 6 6 6 0 CLASP N terminal ANAPC3 PF12895.7 OWF52076.1 - 8.2 6.7 6.3 23 5.3 0.1 4.4 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Lectin_C PF00059.21 OWF52078.1 - 9.2e-18 65.0 0.0 1.3e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain zf-C2H2 PF00096.26 OWF52079.1 - 5.7e-09 35.9 42.3 0.00045 20.5 1.1 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF52079.1 - 3e-08 33.8 40.4 0.011 16.5 2.2 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF52079.1 - 5.3e-06 26.6 0.3 5.3e-06 26.6 0.3 7.1 8 0 0 8 8 8 2 Zinc-finger double domain zf-met PF12874.7 OWF52079.1 - 0.0095 16.3 36.9 0.29 11.6 3.6 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF52079.1 - 9.1 6.7 26.5 7.6 7.0 0.1 5.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding HLH PF00010.26 OWF52080.1 - 2e-15 56.5 3.8 4.5e-15 55.4 3.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF52080.1 - 2.8e-15 56.2 0.1 5.9e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Hairy Orange Staphostatin_B PF09023.10 OWF52080.1 - 0.037 14.1 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Staphostatin B DUF4768 PF15989.5 OWF52081.1 - 0.69 9.9 21.2 68 3.5 2.4 6.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4768) DUF4768 PF15989.5 OWF52082.1 - 0.26 11.2 11.2 11 6.0 0.6 4.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4768) AROS PF15684.5 OWF52083.1 - 7.6e-19 68.5 11.2 9.5e-19 68.2 11.2 1.1 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DUF349 PF03993.12 OWF52083.1 - 0.088 13.1 3.9 0.14 12.4 3.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF1836 PF08876.11 OWF52083.1 - 0.14 12.2 3.0 0.22 11.6 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) 7tm_1 PF00001.21 OWF52084.1 - 2.8e-48 164.5 14.3 3.7e-48 164.2 14.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF621 PF04789.15 OWF52084.1 - 0.00012 21.3 9.3 0.00012 21.3 9.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF621) DUF3262 PF11660.8 OWF52084.1 - 0.026 14.9 0.1 0.026 14.9 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3262) Piezo_RRas_bdg PF12166.8 OWF52084.1 - 0.035 13.4 1.5 0.059 12.7 1.5 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain 7TM_GPCR_Srsx PF10320.9 OWF52084.1 - 0.039 13.3 21.2 0.01 15.3 8.7 2.3 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF52085.1 - 1.4e-55 188.5 23.6 1.8e-55 188.1 23.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF52085.1 - 1.8e-13 50.5 24.7 2.3e-13 50.1 24.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF52085.1 - 1.4e-08 34.8 17.2 1.8e-08 34.5 17.2 1.1 1 0 0 1 1 1 1 Olfactory receptor Pox_A28 PF04584.14 OWF52085.1 - 0.12 12.6 3.7 0.44 10.7 3.7 2.0 1 0 0 1 1 1 0 Poxvirus A28 family DUF948 PF06103.11 OWF52086.1 - 5.3e-22 77.9 45.2 2e-05 24.8 5.8 6.2 1 1 5 6 6 6 6 Bacterial protein of unknown function (DUF948) PMC2NT PF08066.12 OWF52086.1 - 3.5e-15 56.5 57.9 0.08 13.6 3.9 11.1 1 1 8 9 9 9 5 PMC2NT (NUC016) domain RmuC PF02646.16 OWF52086.1 - 6.2e-12 45.3 13.3 0.02 14.0 0.2 5.2 1 1 2 4 4 4 4 RmuC family Sec34 PF04136.15 OWF52086.1 - 4.7e-11 42.8 25.5 0.0049 16.8 1.8 5.0 1 1 3 4 4 4 4 Sec34-like family Pup PF05639.11 OWF52086.1 - 8.2e-10 39.4 58.8 0.17 12.8 0.6 11.1 1 1 8 10 10 9 3 Pup-like protein DUF16 PF01519.16 OWF52086.1 - 1.9e-07 31.5 25.6 0.0057 17.1 1.8 5.1 1 1 4 5 5 5 3 Protein of unknown function DUF16 YkyA PF10368.9 OWF52086.1 - 2.4e-07 30.6 28.9 0.0023 17.6 7.4 3.3 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein Apolipoprotein PF01442.18 OWF52086.1 - 3.7e-07 30.2 0.1 0.038 13.9 0.0 3.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain BLOC1_2 PF10046.9 OWF52086.1 - 8.4e-07 29.2 21.6 0.6 10.5 2.1 6.0 1 1 4 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 OWF52086.1 - 1.2e-06 28.6 13.9 0.0022 18.0 1.3 3.7 1 1 3 4 4 4 3 Laminin Domain II Baculo_PEP_C PF04513.12 OWF52086.1 - 2.1e-06 27.8 15.5 0.0018 18.3 2.6 3.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.6 OWF52086.1 - 2.3e-06 27.6 9.0 2.2 8.2 0.1 5.7 1 1 5 6 6 6 0 Casein Kinase 2 substrate RPW8 PF05659.11 OWF52086.1 - 2.3e-06 27.3 39.4 0.064 13.0 1.0 6.4 1 1 5 6 6 6 3 Arabidopsis broad-spectrum mildew resistance protein RPW8 NPV_P10 PF05531.12 OWF52086.1 - 2.5e-06 27.8 29.9 0.12 12.8 1.1 5.8 1 1 4 5 5 5 3 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 OWF52086.1 - 3.8e-06 25.4 36.3 4e-05 22.0 36.3 2.1 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Dynactin_p22 PF07426.11 OWF52086.1 - 8.5e-06 25.7 18.8 0.53 10.1 5.6 5.6 1 1 4 5 5 5 2 Dynactin subunit p22 DUF2833 PF11090.8 OWF52086.1 - 1e-05 25.8 18.0 16 6.0 0.1 8.5 1 1 6 7 7 7 0 Protein of unknown function (DUF2833) DUF745 PF05335.13 OWF52086.1 - 1.2e-05 25.2 3.0 0.38 10.4 0.2 3.5 1 1 4 5 5 5 1 Protein of unknown function (DUF745) Seryl_tRNA_N PF02403.22 OWF52086.1 - 1.5e-05 25.2 3.8 0.81 10.0 0.1 4.9 1 1 4 5 5 5 1 Seryl-tRNA synthetase N-terminal domain DUF5063 PF16702.5 OWF52086.1 - 3e-05 24.5 25.9 0.005 17.3 3.8 4.5 1 1 3 4 4 4 1 Domain of unknown function (DUF5063) COG5 PF10392.9 OWF52086.1 - 4.1e-05 23.8 22.3 0.032 14.4 1.3 5.0 1 1 4 5 5 5 3 Golgi transport complex subunit 5 Fib_alpha PF08702.10 OWF52086.1 - 4.8e-05 23.6 36.5 0.015 15.5 7.3 3.7 1 1 2 3 3 3 2 Fibrinogen alpha/beta chain family Spc7 PF08317.11 OWF52086.1 - 9.2e-05 21.5 16.3 0.0059 15.5 2.1 2.9 1 1 2 3 3 3 3 Spc7 kinetochore protein DUF3540 PF12059.8 OWF52086.1 - 0.0001 22.2 19.3 0.15 11.9 1.5 4.2 1 1 3 4 4 4 3 Protein of unknown function (DUF3540) CAP_N PF01213.19 OWF52086.1 - 0.00015 21.4 6.8 0.26 10.7 0.3 3.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal DUF2205 PF10224.9 OWF52086.1 - 0.00019 21.3 17.1 1.6 8.8 0.5 6.4 1 1 5 6 6 6 1 Short coiled-coil protein DUF717 PF05338.12 OWF52086.1 - 0.00028 20.9 11.4 39 4.5 0.2 8.9 2 2 6 8 8 8 0 Protein of unknown function (DUF717) DASH_Dad2 PF08654.10 OWF52086.1 - 0.00033 21.0 18.1 9.3 6.7 0.5 6.1 1 1 2 3 3 3 0 DASH complex subunit Dad2 Lipoprotein_2 PF00921.17 OWF52086.1 - 0.00042 20.0 15.4 0.0013 18.4 4.1 2.8 1 1 1 2 2 2 1 Borrelia lipoprotein DUF1664 PF07889.12 OWF52086.1 - 0.00047 20.2 49.1 0.028 14.5 10.5 4.6 1 1 4 5 5 5 1 Protein of unknown function (DUF1664) DUF2397 PF09660.10 OWF52086.1 - 0.0005 19.1 8.9 0.35 9.7 0.5 3.9 1 1 2 3 3 3 2 Protein of unknown function (DUF2397) CREPT PF16566.5 OWF52086.1 - 0.00084 19.5 10.6 1.1 9.4 1.7 3.7 1 1 2 3 3 3 2 Cell-cycle alteration and expression-elevated protein in tumour COG6 PF06419.11 OWF52086.1 - 0.00086 17.7 25.1 0.041 12.1 0.9 4.3 1 1 4 5 5 5 4 Conserved oligomeric complex COG6 TssO PF17561.2 OWF52086.1 - 0.0011 19.1 35.1 2.2 8.4 2.6 6.3 1 1 4 5 5 5 0 Type VI secretion system, TssO UvsY PF11056.8 OWF52086.1 - 0.0012 19.2 33.4 2.4 8.5 0.5 6.3 1 1 4 5 5 5 0 Recombination, repair and ssDNA binding protein UvsY Nup88 PF10168.9 OWF52086.1 - 0.0012 16.7 23.7 0.013 13.3 9.6 2.1 1 1 1 2 2 2 2 Nuclear pore component DUF1043 PF06295.12 OWF52086.1 - 0.0018 18.3 20.7 0.093 12.7 0.7 5.5 1 1 3 5 5 5 1 Protein of unknown function (DUF1043) RasGAP_C PF03836.15 OWF52086.1 - 0.002 18.3 19.0 3.9 7.6 0.9 5.1 1 1 1 2 2 2 0 RasGAP C-terminus DUF1722 PF08349.11 OWF52086.1 - 0.0025 18.1 16.2 0.42 10.9 1.4 4.5 1 1 2 4 4 4 1 Protein of unknown function (DUF1722) Het-C PF07217.11 OWF52086.1 - 0.0026 16.4 34.6 0.11 11.0 14.1 3.8 1 1 2 3 3 3 2 Heterokaryon incompatibility protein Het-C Taxilin PF09728.9 OWF52086.1 - 0.0032 16.7 10.7 0.0058 15.8 6.0 2.4 1 1 1 2 2 2 1 Myosin-like coiled-coil protein T3SSipB PF16535.5 OWF52086.1 - 0.0039 17.7 0.0 13 6.3 0.0 4.1 1 1 4 5 5 5 0 Type III cell invasion protein SipB CorA PF01544.18 OWF52086.1 - 0.0042 16.4 40.0 0.84 8.9 9.5 4.1 1 1 2 3 3 3 1 CorA-like Mg2+ transporter protein HBM PF16591.5 OWF52086.1 - 0.0045 16.4 0.2 4.5 6.6 0.1 2.8 2 2 0 2 2 2 0 Helical bimodular sensor domain DHR10 PF18595.1 OWF52086.1 - 0.0054 16.8 9.2 8.4 6.5 0.2 4.6 1 1 2 4 4 4 0 Designed helical repeat protein 10 domain Noelin-1 PF12308.8 OWF52086.1 - 0.0076 16.2 24.1 0.28 11.2 2.2 5.0 1 1 4 5 5 5 1 Neurogenesis glycoprotein ISG65-75 PF11727.8 OWF52086.1 - 0.0076 15.5 38.3 0.079 12.2 5.9 4.8 1 1 4 5 5 5 2 Invariant surface glycoprotein THOC7 PF05615.13 OWF52086.1 - 0.0082 16.4 9.9 0.56 10.5 1.7 2.8 1 1 1 2 2 2 2 Tho complex subunit 7 RAC_head PF16717.5 OWF52086.1 - 0.014 16.4 37.1 6.2 7.9 1.2 8.1 1 1 5 6 6 6 0 Ribosome-associated complex head domain COG2 PF06148.11 OWF52086.1 - 0.023 14.8 12.8 1.7 8.7 2.3 4.8 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3829 PF12889.7 OWF52086.1 - 0.024 14.1 17.6 0.51 9.8 2.3 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3829) MCPsignal PF00015.21 OWF52086.1 - 0.024 14.4 48.0 0.25 11.1 9.0 5.1 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spectrin PF00435.21 OWF52086.1 - 0.025 15.1 14.9 3.1 8.3 1.3 4.6 1 1 4 5 5 5 0 Spectrin repeat Dor1 PF04124.12 OWF52086.1 - 0.035 12.8 17.7 0.37 9.4 1.3 4.3 1 1 3 4 4 4 0 Dor1-like family DASH_Duo1 PF08651.10 OWF52086.1 - 0.039 13.7 39.0 0.86 9.4 1.6 7.0 2 2 3 5 5 5 0 DASH complex subunit Duo1 P4Ha_N PF08336.11 OWF52086.1 - 0.049 13.7 19.0 7.5 6.6 1.8 5.5 1 1 4 5 5 5 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HsbA PF12296.8 OWF52086.1 - 0.055 13.9 11.3 8.1 6.9 1.0 5.4 1 1 2 4 4 4 0 Hydrophobic surface binding protein A ZapB PF06005.12 OWF52086.1 - 0.057 13.9 0.3 15 6.1 0.0 4.2 2 2 1 3 3 2 0 Cell division protein ZapB Goodbye PF17109.5 OWF52086.1 - 0.066 13.7 12.9 4.4 7.8 0.8 5.1 1 1 3 4 4 4 0 fungal STAND N-terminal Goodbye domain MAAL_C PF07476.11 OWF52086.1 - 0.085 12.0 23.6 0.75 8.9 1.2 3.8 1 1 3 4 4 4 0 Methylaspartate ammonia-lyase C-terminus PHA_synth_III_E PF09712.10 OWF52086.1 - 0.086 11.9 6.6 1.2 8.1 0.3 2.9 1 1 1 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) FAP206 PF12018.8 OWF52086.1 - 0.097 12.2 20.4 0.53 9.7 3.9 3.9 1 1 4 5 5 5 0 Domain of unknown function Mce4_CUP1 PF11887.8 OWF52086.1 - 0.11 11.9 13.9 2.7 7.4 0.6 3.4 1 1 3 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative Csm2_III-A PF03750.13 OWF52086.1 - 0.14 13.0 2.8 27 5.6 0.0 3.9 1 1 1 3 3 3 0 Csm2 Type III-A TMPIT PF07851.13 OWF52086.1 - 0.15 11.3 20.0 1.8e+04 -6.2 19.8 3.8 1 1 0 1 1 0 0 TMPIT-like protein Med30 PF11315.8 OWF52086.1 - 0.17 12.1 32.5 3 8.0 4.2 4.8 1 1 3 4 4 4 0 Mediator complex subunit 30 ANAPC4 PF12896.7 OWF52086.1 - 0.18 11.3 28.7 3.4 7.1 1.4 5.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 Laminin_I PF06008.14 OWF52086.1 - 0.2 11.4 26.4 0.65 9.7 4.7 4.2 1 1 5 6 6 6 0 Laminin Domain I DASH_Dad1 PF08649.10 OWF52086.1 - 0.21 11.8 12.8 27 5.1 0.1 6.0 3 2 3 6 6 5 0 DASH complex subunit Dad1 HrpB7 PF09486.10 OWF52086.1 - 0.21 11.9 1.6 3.9 7.8 0.1 2.9 1 1 2 3 3 2 0 Bacterial type III secretion protein (HrpB7) IZUMO PF15005.6 OWF52086.1 - 0.22 12.1 19.3 13 6.3 1.4 4.7 1 1 4 5 5 5 0 Izumo sperm-egg fusion, Ig domain-associated MitMem_reg PF13012.6 OWF52086.1 - 0.24 11.9 28.6 7.3 7.0 2.3 4.4 1 1 3 4 4 4 0 Maintenance of mitochondrial structure and function DUF148 PF02520.17 OWF52086.1 - 0.29 11.3 25.0 6.2 7.0 2.2 4.8 1 1 4 5 5 5 0 Domain of unknown function DUF148 Tropomyosin PF00261.20 OWF52086.1 - 0.32 10.3 17.1 4.5 6.6 10.3 3.5 1 1 0 2 2 2 0 Tropomyosin Spore_II_R PF09551.10 OWF52086.1 - 0.33 11.4 25.3 12 6.4 0.6 5.6 1 1 3 4 4 4 0 Stage II sporulation protein R (spore_II_R) Rogdi_lz PF10259.9 OWF52086.1 - 0.36 10.2 16.1 4.3 6.7 0.8 4.4 1 1 3 4 4 4 0 Rogdi leucine zipper containing protein Med27 PF11571.8 OWF52086.1 - 0.39 11.1 2.5 3.1 8.2 0.1 3.6 2 1 0 3 3 2 0 Mediator complex subunit 27 PTPA PF03095.15 OWF52086.1 - 0.4 10.1 16.8 3.2 7.1 1.4 3.6 1 1 2 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein Glu-tRNAGln PF02686.15 OWF52086.1 - 0.41 11.0 47.0 12 6.3 1.5 8.8 1 1 5 6 6 5 0 Glu-tRNAGln amidotransferase C subunit APG17 PF04108.12 OWF52086.1 - 0.42 9.7 47.5 0.13 11.3 18.0 2.7 1 1 1 2 2 2 0 Autophagy protein Apg17 Death PF00531.22 OWF52086.1 - 0.42 10.8 7.0 35 4.6 0.2 5.2 1 1 5 6 6 6 0 Death domain UTP15_C PF09384.10 OWF52086.1 - 0.73 9.5 26.3 3.8 7.2 0.4 5.0 1 1 4 5 5 5 0 UTP15 C terminal DUF3450 PF11932.8 OWF52086.1 - 0.9 8.8 11.2 3.1 7.1 1.4 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DivIVA PF05103.13 OWF52086.1 - 0.94 9.6 13.8 4.2 7.4 0.1 4.5 1 1 3 5 5 5 0 DivIVA protein Serine_rich PF08824.10 OWF52086.1 - 1 9.4 14.4 0.76 9.8 3.7 3.3 1 1 1 2 2 2 0 Serine rich protein interaction domain AIP3 PF03915.13 OWF52086.1 - 1.2 8.2 33.1 0.47 9.5 19.2 2.4 1 1 1 2 2 2 0 Actin interacting protein 3 DUF4208 PF13907.6 OWF52086.1 - 1.3 9.6 21.0 0.83 10.1 0.7 4.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4208) HMMR_N PF15905.5 OWF52086.1 - 1.7 8.0 18.8 1.1 8.7 7.4 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fer4_24 PF18109.1 OWF52086.1 - 1.9 8.9 52.7 23 5.4 0.3 13.1 8 4 6 14 14 13 0 Ferredoxin I 4Fe-4S cluster domain Cbl_N PF02262.16 OWF52086.1 - 2 8.4 7.9 73 3.4 2.6 3.9 1 1 2 3 3 3 0 CBL proto-oncogene N-terminal domain 1 LXG PF04740.12 OWF52086.1 - 2.1 8.0 49.1 4.4 7.0 13.3 4.3 1 1 3 4 4 4 0 LXG domain of WXG superfamily IFT57 PF10498.9 OWF52086.1 - 2.3 7.1 42.3 0.39 9.6 5.0 4.3 1 1 2 4 4 4 0 Intra-flagellar transport protein 57 DUF2120 PF09893.9 OWF52086.1 - 2.4 8.3 41.5 9.6 6.3 10.8 5.1 1 1 2 3 3 2 0 Uncharacterized protein conserved in archaea (DUF2120) Lipoprotein_7 PF01540.16 OWF52086.1 - 2.5 7.3 20.6 1.3 8.3 13.4 2.2 1 1 1 2 2 2 0 Adhesin lipoprotein SEO_N PF14576.6 OWF52086.1 - 2.5 7.2 41.1 0.19 10.8 3.6 3.9 1 1 2 3 3 3 0 Sieve element occlusion N-terminus Hormone_1 PF00103.20 OWF52086.1 - 2.7 7.7 24.9 13 5.5 1.9 5.0 1 1 3 4 4 4 0 Somatotropin hormone family NACHT_N PF17100.5 OWF52086.1 - 3.2 7.5 19.4 4.6 7.0 1.3 4.1 1 1 5 6 6 6 0 N-terminal domain of NWD NACHT-NTPase ING PF12998.7 OWF52086.1 - 4.3 8.0 34.8 2.9 8.5 5.9 4.7 1 1 3 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding YabA PF06156.13 OWF52086.1 - 4.6 7.9 39.2 16 6.2 1.2 6.1 1 1 3 4 4 3 0 Initiation control protein YabA Peptidase_C65 PF10275.9 OWF52086.1 - 4.7 6.6 31.1 4.5 6.6 2.2 4.2 1 1 3 4 4 4 0 Peptidase C65 Otubain UPF0242 PF06785.11 OWF52086.1 - 4.7 7.3 18.1 5.1 7.2 1.3 3.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MukB PF04310.12 OWF52086.1 - 5.2 6.8 17.2 3.4 7.4 0.7 3.5 1 1 3 4 4 4 0 MukB N-terminal Tropomyosin_1 PF12718.7 OWF52086.1 - 5.4 7.2 14.5 15 5.7 0.8 3.5 1 1 3 4 4 4 0 Tropomyosin like EMP24_GP25L PF01105.24 OWF52086.1 - 5.7 6.8 41.5 12 5.8 1.3 6.4 1 1 3 4 4 2 0 emp24/gp25L/p24 family/GOLD Bac_globin PF01152.21 OWF52086.1 - 6.4 6.9 45.5 9.5 6.4 1.5 6.9 1 1 6 7 7 7 0 Bacterial-like globin SPG48 PF14764.6 OWF52086.1 - 7 7.2 9.7 55 4.3 0.2 3.8 1 1 2 4 4 4 0 AP-5 complex subunit, vesicle trafficking Folliculin PF11704.8 OWF52086.1 - 7.2 6.4 23.8 0.35 10.7 5.7 4.8 1 1 1 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport Baculo_IE-1 PF05290.11 OWF52086.1 - 7.7 6.5 25.1 37 4.3 1.1 5.9 1 1 6 7 7 7 0 Baculovirus immediate-early protein (IE-0) Njmu-R1 PF15053.6 OWF52087.1 - 7.2e-52 176.6 12.6 8.3e-51 173.2 12.6 2.1 1 1 0 1 1 1 1 Mjmu-R1-like protein family REPA_OB_2 PF16900.5 OWF52088.1 - 2.6e-15 56.1 0.2 6.4e-11 42.0 0.5 2.5 2 0 0 2 2 2 2 Replication protein A OB domain CDC24_OB3 PF17244.2 OWF52088.1 - 7.1e-05 22.6 0.9 0.00014 21.7 0.9 1.4 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 MTHFR_C PF12225.8 OWF52088.1 - 0.00034 20.2 1.4 0.00041 19.9 0.2 1.8 2 0 0 2 2 2 1 Methylene-tetrahydrofolate reductase C terminal Rep_fac-A_C PF08646.10 OWF52088.1 - 0.0047 16.7 3.5 0.026 14.3 0.2 2.8 2 1 1 3 3 3 1 Replication factor-A C terminal domain Ribosomal_L44 PF00935.19 OWF52088.1 - 2.7 8.5 7.2 9.5 6.8 0.7 2.6 2 0 0 2 2 2 0 Ribosomal protein L44 RRM_1 PF00076.22 OWF52089.1 - 9.3e-32 108.7 0.1 3.2e-18 65.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF52089.1 - 0.0037 17.3 0.0 0.014 15.5 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif ANAPC4_WD40 PF12894.7 OWF52090.1 - 0.0015 18.8 0.0 1.1 9.6 0.0 4.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF52090.1 - 0.0081 17.0 0.0 13 6.8 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat VID27 PF08553.10 OWF52090.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain LRR_8 PF13855.6 OWF52092.1 - 1.5e-20 72.7 5.6 1.5e-11 43.9 2.0 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OWF52092.1 - 5.1e-16 58.5 5.3 0.0001 22.6 0.0 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF52092.1 - 2.2e-07 30.5 4.3 3.9 8.4 0.1 5.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 OWF52092.1 - 1.3e-05 24.8 8.6 0.00018 21.1 2.4 1.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OWF52092.1 - 0.00058 19.7 9.9 13 6.1 0.9 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 OWF52093.1 - 8.9e-15 54.2 1.2 2.4e-07 30.4 0.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF52093.1 - 1.5e-13 50.6 4.7 5.5e-05 23.4 0.1 3.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OWF52093.1 - 8.7e-08 31.6 3.1 2.2 8.6 0.0 4.9 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 OWF52093.1 - 2.1e-06 27.5 6.8 3.5 8.5 0.0 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 OWF52093.1 - 0.00022 20.8 0.6 0.0004 19.9 0.4 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 OWF52094.1 - 6.3e-07 28.9 24.3 0.0011 18.8 0.2 6.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 OWF52094.1 - 0.0095 16.4 3.3 16 6.5 0.1 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat MAP PF03642.13 OWF52094.1 - 0.68 10.3 6.7 2 8.8 0.2 3.7 3 1 1 4 4 4 0 MAP domain HU-CCDC81_bac_2 PF18175.1 OWF52094.1 - 0.85 9.5 7.1 0.14 12.1 0.3 3.3 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Sulfatase PF00884.23 OWF52095.1 - 1.1e-52 179.4 0.0 3.9e-52 177.6 0.0 1.9 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OWF52095.1 - 5.6e-14 52.2 4.2 2.3e-09 37.5 1.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 OWF52095.1 - 6.4e-05 22.7 0.0 0.02 14.5 0.0 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OWF52095.1 - 0.042 14.6 1.4 0.12 13.1 1.4 1.7 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 OWF52095.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfate_transp PF00916.20 OWF52096.1 - 2e-97 326.3 18.4 2.6e-97 326.0 18.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OWF52096.1 - 1.4e-11 44.0 0.3 2.8e-11 43.1 0.3 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OWF52096.1 - 0.0072 16.7 2.4 0.0072 16.7 2.4 3.4 2 2 2 4 4 4 1 Molybdate transporter of MFS superfamily DUF5408 PF17402.2 OWF52096.1 - 0.01 15.7 1.0 0.063 13.2 0.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5408) STAS_2 PF13466.6 OWF52096.1 - 0.03 14.7 0.0 0.091 13.1 0.0 1.7 2 0 0 2 2 2 0 STAS domain Na_H_antiport_2 PF13726.6 OWF52096.1 - 1.4 9.1 7.8 0.15 12.3 1.4 2.8 3 0 0 3 3 3 0 Na+-H+ antiporter family Pkinase PF00069.25 OWF52097.1 - 3.4e-75 252.8 0.0 5.1e-75 252.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 OWF52097.1 - 1.4e-56 190.1 0.1 3e-56 189.1 0.1 1.6 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 OWF52097.1 - 9.9e-34 116.8 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4440 PF14534.6 OWF52097.1 - 1.3e-09 38.4 0.0 2.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 OWF52097.1 - 3.1e-09 37.1 0.0 5.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.23 OWF52097.1 - 0.00017 21.6 0.1 0.59 10.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF52097.1 - 0.00094 18.1 0.0 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF52097.1 - 0.0049 16.2 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OWF52097.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OWF52097.1 - 0.15 11.4 0.9 1 8.6 0.0 2.3 1 1 1 2 2 2 0 Kinase-like 3Beta_HSD PF01073.19 OWF52098.1 - 2.8e-60 203.7 0.0 4.6e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OWF52098.1 - 5.2e-31 107.9 0.0 7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OWF52098.1 - 2.1e-13 50.0 0.0 3.2e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OWF52098.1 - 2.8e-13 50.0 0.0 5.6e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OWF52098.1 - 2.5e-10 40.5 0.0 4.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OWF52098.1 - 1.2e-08 34.4 0.0 2.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OWF52098.1 - 2.5e-08 33.4 0.0 5.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OWF52098.1 - 0.0027 17.3 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family ESSS PF10183.9 OWF52098.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SHIPPO-rpt PF07004.12 OWF52099.1 - 1.3e-08 35.3 25.4 0.025 15.5 2.5 6.6 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat SHIPPO-rpt PF07004.12 OWF52100.1 - 7.1e-06 26.7 11.6 2.2 9.3 0.1 4.7 4 1 0 4 4 4 4 Sperm-tail PG-rich repeat HMMR_N PF15905.5 OWF52100.1 - 0.22 11.0 0.7 6.6 6.1 0.3 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TFIIA PF03153.13 OWF52101.1 - 0.0044 17.1 17.1 0.005 16.9 17.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Plasmodium_HRP PF05403.11 OWF52101.1 - 0.0085 15.9 3.1 0.013 15.3 3.1 1.2 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) Macoilin PF09726.9 OWF52101.1 - 0.069 11.7 22.4 0.072 11.6 22.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF966 PF06136.13 OWF52101.1 - 0.21 11.3 16.2 0.24 11.1 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2981 PF11200.8 OWF52101.1 - 1.5 8.5 11.3 1.7 8.3 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) LAP1C PF05609.12 OWF52101.1 - 1.5 7.8 19.4 1.9 7.5 19.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 OWF52101.1 - 1.6 7.3 16.5 1.9 7.1 16.5 1.1 1 0 0 1 1 1 0 Hamartin protein CDK5_activator PF03261.15 OWF52101.1 - 1.7 8.1 29.6 2.5 7.6 29.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Utp14 PF04615.13 OWF52101.1 - 2.4 6.6 21.9 2.8 6.4 21.9 1.0 1 0 0 1 1 1 0 Utp14 protein Endomucin PF07010.12 OWF52101.1 - 5.1 7.0 25.9 7.1 6.5 25.9 1.2 1 0 0 1 1 1 0 Endomucin GREB1 PF15782.5 OWF52101.1 - 5.2 4.1 20.2 5.9 3.9 20.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UPA PF17217.3 OWF52102.1 - 1.2e-50 171.1 0.0 2.1e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 OWF52102.1 - 6.1e-32 109.9 0.0 6.9e-30 103.3 0.0 2.7 2 0 0 2 2 2 1 ZU5 domain Death PF00531.22 OWF52102.1 - 1.2e-14 54.2 0.0 2.4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Death domain TSP_1 PF00090.19 OWF52102.1 - 3.5e-12 46.3 28.2 7.9e-10 38.8 10.9 2.9 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_3 PF13927.6 OWF52102.1 - 4.4e-11 43.2 0.0 3e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OWF52102.1 - 1.9e-09 37.4 0.0 4.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF52102.1 - 3e-07 30.7 1.5 7.5e-06 26.2 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 OWF52102.1 - 2.3e-06 27.7 0.0 8.3e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 OWF52102.1 - 0.00014 21.3 0.0 0.00037 20.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 OWF52102.1 - 0.00015 21.7 0.0 0.059 13.4 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 OWF52102.1 - 0.0036 17.5 0.5 2 8.6 0.0 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain EphA2_TM PF14575.6 OWF52102.1 - 0.14 13.1 0.0 0.3 12.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1451 PF07295.11 OWF52103.1 - 0.064 13.3 0.4 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF5460 PF17544.2 OWF52103.1 - 0.073 12.1 0.1 0.54 9.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5460) DUF1397 PF07165.11 OWF52103.1 - 0.13 11.7 2.4 4.6 6.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) Ant_C PF05586.11 OWF52103.1 - 0.16 12.6 0.0 1.9 9.1 0.0 2.4 2 0 0 2 2 2 0 Anthrax receptor C-terminus region DUF5009 PF16401.5 OWF52104.1 - 1.5e-06 27.9 3.2 1.5e-06 27.9 3.2 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) ArfGap PF01412.18 OWF52105.1 - 0.099 12.7 0.9 1.5 8.9 0.1 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf DUF3574 PF12098.8 OWF52105.1 - 0.1 12.4 4.3 2 8.2 0.1 3.2 1 1 2 4 4 4 0 Protein of unknown function (DUF3574) DUF2171 PF09939.9 OWF52105.1 - 0.15 12.3 12.6 0.54 10.6 1.5 3.6 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2171) STAS_2 PF13466.6 OWF52105.1 - 2.5 8.5 22.9 16 5.9 2.3 6.9 1 1 6 7 7 7 0 STAS domain RHH_1 PF01402.21 OWF52105.1 - 4 7.5 15.7 38 4.4 0.2 6.1 4 3 3 7 7 7 0 Ribbon-helix-helix protein, copG family PI3K_C2 PF00792.24 OWF52107.1 - 1.8e-07 31.1 6.0 0.019 14.9 1.7 3.7 1 1 1 2 2 2 2 Phosphoinositide 3-kinase C2 APC_u13 PF16634.5 OWF52107.1 - 2.9e-05 23.9 18.0 2.5 8.1 0.1 5.6 1 1 4 5 5 5 4 Unstructured region on APC between APC_crr and SAMP Chordopox_G3 PF06129.12 OWF52107.1 - 0.0069 17.1 6.0 3.4 8.4 0.9 2.9 1 1 2 3 3 3 3 Chordopoxvirus G3 protein DUF1771 PF08590.10 OWF52107.1 - 0.01 16.2 0.1 22 5.5 0.0 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF1771) Sec2p PF06428.11 OWF52107.1 - 0.012 15.6 3.1 12 6.0 0.2 3.6 1 1 3 4 4 4 0 GDP/GTP exchange factor Sec2p PAS_7 PF12860.7 OWF52107.1 - 0.02 15.0 0.0 1.4 9.1 0.0 2.3 1 1 1 2 2 2 0 PAS fold Vta1 PF04652.16 OWF52107.1 - 0.62 10.0 4.9 31 4.5 0.2 3.6 1 1 2 3 3 3 0 Vta1 like PHM7_cyt PF14703.6 OWF52107.1 - 4.1 7.6 6.6 18 5.5 0.5 2.3 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter GvpH PF05455.11 OWF52108.1 - 0.084 12.9 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 GvpH Roc PF08477.13 OWF52110.1 - 4.9e-11 42.9 0.0 1.7e-07 31.4 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF52110.1 - 5.8e-07 29.5 0.1 1.6e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 OWF52110.1 - 1.3e-06 28.9 0.0 2.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ras PF00071.22 OWF52110.1 - 2e-05 24.3 0.6 0.018 14.6 0.0 3.0 3 0 0 3 3 3 2 Ras family Ank_5 PF13857.6 OWF52110.1 - 0.00015 22.0 0.1 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF52110.1 - 0.00018 22.0 0.0 0.00053 20.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) ABC_tran PF00005.27 OWF52110.1 - 0.1 13.1 0.2 0.61 10.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 OWF52110.1 - 0.14 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF5352 PF17303.2 OWF52110.1 - 0.29 11.0 1.7 1.6 8.5 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5352) DUF1657 PF07870.11 OWF52113.1 - 0.0046 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1657) Coagulase PF08764.10 OWF52113.1 - 0.046 13.9 0.1 0.081 13.1 0.1 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase SUI1 PF01253.22 OWF52113.1 - 0.076 13.5 0.0 0.85 10.2 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor SUI1 CheX PF13690.6 OWF52113.1 - 0.092 12.9 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX NusG_add PF18298.1 OWF52114.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 NusG additional domain Sec7 PF01369.20 OWF52115.1 - 0.09 12.5 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Sec7 domain Myb_DNA-bind_4 PF13837.6 OWF52116.1 - 7.2e-05 23.1 0.1 7.2e-05 23.1 0.1 2.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1170 PF06663.13 OWF52116.1 - 0.002 17.9 0.5 0.002 17.9 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1170) Methyltr_RsmB-F PF01189.17 OWF52116.1 - 0.0053 16.4 0.2 0.0085 15.7 0.1 1.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Sod_Ni PF09055.11 OWF52116.1 - 0.011 16.3 1.3 0.015 15.9 1.1 1.4 1 1 0 1 1 1 0 Nickel-containing superoxide dismutase zf-C2H2 PF00096.26 OWF52118.1 - 7.5e-45 148.9 178.8 9.5e-05 22.7 4.9 20.3 20 0 0 20 20 20 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF52118.1 - 3.2e-43 142.6 175.6 0.00056 20.5 1.1 20.9 21 0 0 21 21 20 18 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF52118.1 - 5.7e-41 137.2 147.7 3.9e-09 36.5 0.4 23.3 23 1 0 23 23 22 11 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF52118.1 - 2.2e-10 40.1 22.9 2.3e-09 36.8 1.7 15.6 17 0 0 17 17 16 8 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OWF52118.1 - 3.9e-07 29.9 2.6 0.00036 20.4 0.1 16.6 20 0 0 20 20 20 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF52118.1 - 0.0089 16.3 111.4 0.19 12.1 0.1 17.6 20 0 0 20 20 19 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF52118.1 - 0.016 15.6 0.1 0.016 15.6 0.1 15.3 17 0 0 17 17 16 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF52118.1 - 0.022 15.0 0.4 0.022 15.0 0.4 10.2 10 1 0 10 10 10 0 C2H2-type zinc ribbon BolA PF01722.18 OWF52118.1 - 0.19 12.0 12.0 4.3 7.7 0.6 4.5 4 1 0 4 4 3 0 BolA-like protein zf-CHCC PF10276.9 OWF52118.1 - 0.25 11.4 12.3 33 4.6 0.2 5.8 4 0 0 4 4 4 0 Zinc-finger domain PyrI_C PF02748.15 OWF52118.1 - 2.6 8.0 19.9 9.1 6.3 0.1 7.6 8 0 0 8 8 8 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ABC1 PF03109.16 OWF52119.1 - 1.3e-33 115.6 0.0 3.1e-33 114.4 0.0 1.7 1 0 0 1 1 1 1 ABC1 family HrpB2 PF09487.10 OWF52119.1 - 0.066 13.6 0.0 0.46 10.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Zn-ribbon_8 PF09723.10 OWF52119.1 - 0.099 12.8 0.1 20 5.4 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-FCS PF06467.14 OWF52119.1 - 0.16 12.0 0.4 0.38 10.7 0.4 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif SNF PF00209.18 OWF52121.1 - 1.2e-146 489.4 34.1 1.8e-146 488.9 34.1 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tsg PF04668.12 OWF52122.1 - 9.1e-42 142.9 4.1 9.1e-42 142.9 4.1 2.6 2 0 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region Epiglycanin_TR PF05647.11 OWF52123.1 - 0.071 13.0 3.6 0.22 11.5 3.6 1.8 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like HC2 PF07382.11 OWF52124.1 - 2.3e-10 40.9 27.9 2.6e-06 27.6 17.1 2.2 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 PGI PF00342.19 OWF52125.1 - 2.7e-230 765.1 4.7 6.5e-206 684.6 0.2 2.3 2 1 1 3 3 3 2 Phosphoglucose isomerase TDP43_N PF18694.1 OWF52126.1 - 1e-32 111.8 0.0 1.9e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 OWF52126.1 - 1.6e-24 85.5 0.1 2.4e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF52126.1 - 1.4e-06 28.4 0.1 0.069 13.3 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif RL PF17797.1 OWF52126.1 - 5.5e-05 23.0 0.0 0.029 14.3 0.0 2.4 2 0 0 2 2 2 2 RL domain GRP PF07172.11 OWF52126.1 - 0.39 11.4 15.1 1.2 9.8 2.4 2.3 2 0 0 2 2 2 0 Glycine rich protein family RRM_1 PF00076.22 OWF52127.1 - 1.7e-13 50.2 0.1 3.6e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HGTP_anticodon PF03129.20 OWF52127.1 - 5.6e-05 23.2 0.1 9.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain RRM_7 PF16367.5 OWF52127.1 - 0.027 14.6 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif Anillin PF08174.11 OWF52128.1 - 4.5e-24 85.5 0.1 2.8e-23 82.9 0.0 2.5 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 OWF52128.1 - 1.8e-16 60.5 0.3 9.9e-16 58.2 0.0 2.5 2 0 0 2 2 2 1 PH domain Anillin_N PF16018.5 OWF52128.1 - 2.4e-10 40.9 3.0 2.4e-10 40.9 3.0 6.7 5 1 0 5 5 5 2 Anillin N-terminus Lipase_GDSL PF00657.22 OWF52129.1 - 9.5e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cu-binding_MopE PF11617.8 OWF52129.1 - 0.00031 20.8 3.1 0.0011 19.1 3.1 2.0 1 1 0 1 1 1 1 Putative metal-binding motif Lipase_GDSL_2 PF13472.6 OWF52129.1 - 0.00046 20.6 0.9 0.075 13.4 0.5 3.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family SSF PF00474.17 OWF52130.1 - 8.4e-09 34.8 4.8 1.2e-08 34.2 4.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 OWF52131.1 - 6.5e-19 68.1 19.3 1.8e-18 66.6 19.3 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 OWF52132.1 - 2.7e-27 95.7 28.2 8.7e-27 94.0 28.2 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 OWF52133.1 - 1.1e-28 100.3 28.8 3e-28 98.8 28.8 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family 7tm_1 PF00001.21 OWF52134.1 - 5.1e-17 62.1 15.4 5.1e-17 62.1 15.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATG16 PF08614.11 OWF52135.1 - 0.22 11.7 38.3 91 3.2 33.4 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) A2M_recep PF07677.14 OWF52135.1 - 0.29 11.8 1.7 0.72 10.6 0.2 2.6 2 1 0 2 2 2 0 A-macroglobulin receptor binding domain Tropomyosin PF00261.20 OWF52135.1 - 0.37 10.1 32.2 0.71 9.2 18.2 2.9 1 1 1 2 2 2 0 Tropomyosin AAA_25 PF13481.6 OWF52135.1 - 0.61 9.6 5.1 0.4 10.2 0.3 2.5 2 1 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 OWF52135.1 - 1.1 9.3 10.8 5.2 7.1 2.7 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 OWF52135.1 - 2 8.5 32.3 0.072 13.1 6.4 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5339 PF17274.2 OWF52135.1 - 3.2 8.7 10.5 3.3 8.6 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5339) V-SNARE PF05008.15 OWF52135.1 - 4.7 7.7 18.4 0.25 11.7 7.8 3.8 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Fib_alpha PF08702.10 OWF52135.1 - 4.7 7.4 26.9 6.9 6.9 3.0 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3037 PF11236.8 OWF52135.1 - 6.3 7.3 8.1 4.7 7.7 1.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) IFT57 PF10498.9 OWF52135.1 - 8.4 5.3 26.9 1.3 7.9 11.8 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 PfkB PF00294.24 OWF52136.1 - 3.7e-32 111.9 0.0 4.4e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ABC_transp_aux PF09822.9 OWF52136.1 - 0.045 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system THAP PF05485.12 OWF52137.1 - 4.2e-10 40.4 1.0 4.4e-10 40.4 1.0 1.0 1 0 0 1 1 1 1 THAP domain DUF1619 PF07773.11 OWF52138.1 - 2.7e-45 155.7 23.1 3.8e-44 151.9 15.6 3.7 3 1 0 3 3 3 2 Protein of unknown function (DUF1619) Med3 PF11593.8 OWF52138.1 - 1.6 7.9 9.3 4.2 6.5 9.3 1.7 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAF1 PF04857.20 OWF52139.1 - 2.2e-81 273.5 5.7 2.7e-81 273.2 5.7 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 OWF52139.1 - 3.9e-05 23.6 0.1 0.0001 22.2 0.1 1.8 1 0 0 1 1 1 1 RNA binding domain UCH PF00443.29 OWF52140.1 - 1.6e-75 253.9 0.2 2.7e-75 253.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OWF52140.1 - 1.6e-21 76.8 0.0 8.6e-21 74.4 0.0 2.4 1 1 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 OWF52140.1 - 1.2e-15 58.0 0.9 7.4e-09 35.6 1.4 2.9 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 OWF52140.1 - 3.2e-10 40.3 1.1 3.3e-05 24.3 0.8 3.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF52140.1 - 1.1e-09 37.2 0.4 0.0034 16.8 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OWF52140.1 - 2.1e-08 33.5 0.6 0.025 14.5 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OWF52140.1 - 6e-08 31.8 0.4 0.0074 15.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OWF52140.1 - 1.8e-05 24.5 0.1 0.0039 17.0 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair Ubiquitin_3 PF14836.6 OWF52140.1 - 4e-05 23.5 0.4 0.0001 22.2 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain SET PF00856.28 OWF52141.1 - 8e-18 65.4 0.3 8e-18 65.4 0.3 4.8 2 1 1 3 3 3 1 SET domain N-SET PF11764.8 OWF52141.1 - 1.7e-11 44.5 0.4 3.6e-09 36.9 0.0 6.3 4 3 2 6 6 6 2 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 OWF52141.1 - 1.3e-07 31.3 0.1 2.6e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MotB_plug PF13677.6 OWF52142.1 - 0.027 14.1 0.0 0.027 14.1 0.0 3.3 3 0 0 3 3 3 0 Membrane MotB of proton-channel complex MotA/MotB EIIA-man PF03610.16 OWF52142.1 - 0.04 14.1 0.7 1.2 9.4 0.3 2.9 2 0 0 2 2 2 0 PTS system fructose IIA component BTB PF00651.31 OWF52143.1 - 1.2e-25 89.8 0.9 1.2e-24 86.7 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF52143.1 - 4e-13 49.3 0.2 2.6e-12 46.7 0.1 2.3 2 1 0 2 2 2 1 BTB And C-terminal Kelch PHR PF08005.12 OWF52143.1 - 2.4e-12 47.8 0.1 4.6e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 PHR domain DUF4065 PF13274.6 OWF52143.1 - 0.075 13.9 0.1 6.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Thioredoxin_2 PF13098.6 OWF52143.1 - 0.16 12.5 0.3 0.43 11.1 0.1 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain UQ_con PF00179.26 OWF52144.1 - 3.8e-44 149.8 0.2 4.3e-44 149.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OWF52144.1 - 9.7e-06 25.3 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OWF52144.1 - 3.9e-05 23.9 0.4 5.4e-05 23.5 0.4 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 OWF52144.1 - 4e-05 23.4 0.1 5.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 UEV domain BRE PF06113.12 OWF52144.1 - 0.092 11.6 0.1 0.14 11.0 0.1 1.3 1 1 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) DER1 PF04511.15 OWF52145.1 - 2.3e-73 246.2 14.5 2.6e-73 246.0 14.5 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 OWF52145.1 - 0.0025 17.6 1.0 0.0063 16.3 0.0 1.9 1 1 1 2 2 2 1 Oleosin Sds3 PF08598.11 OWF52146.1 - 5.9e-17 62.4 15.6 5.9e-17 62.4 15.6 1.5 1 1 1 2 2 2 1 Sds3-like CAMSAP_CC1 PF17095.5 OWF52146.1 - 2.6 8.0 7.1 1.1 9.1 0.1 2.9 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Peptidase_A22B PF04258.13 OWF52147.1 - 1.5e-89 300.3 14.7 2.1e-89 299.8 14.7 1.1 1 0 0 1 1 1 1 Signal peptide peptidase MMR_HSR1 PF01926.23 OWF52148.1 - 9.4e-18 64.4 0.1 3.5e-17 62.5 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF52148.1 - 2.4e-09 37.0 0.6 0.0013 18.3 0.2 3.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OWF52148.1 - 1e-06 28.9 0.5 1e-06 28.9 0.5 3.3 3 2 1 4 4 4 1 Dynamin family FeoB_N PF02421.18 OWF52148.1 - 1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF52148.1 - 7.4e-05 22.7 0.8 0.27 11.1 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 OWF52148.1 - 0.00011 21.7 0.7 0.068 12.6 0.3 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family PduV-EutP PF10662.9 OWF52148.1 - 0.00097 18.9 0.1 0.2 11.4 0.1 3.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 OWF52148.1 - 0.0015 17.9 0.0 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family ATP_bind_1 PF03029.17 OWF52148.1 - 0.0024 17.7 0.4 0.13 12.1 0.1 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 OWF52148.1 - 0.0042 16.7 0.5 0.019 14.6 0.1 2.2 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KH_2 PF07650.17 OWF52148.1 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 KH domain AAA_18 PF13238.6 OWF52148.1 - 0.0065 17.0 0.0 0.032 14.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF2201_N PF13203.6 OWF52148.1 - 0.0071 16.0 2.5 0.018 14.6 2.5 1.6 1 0 0 1 1 1 1 Putative metallopeptidase domain KH_1 PF00013.29 OWF52148.1 - 0.0082 16.0 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 KH domain Roc PF08477.13 OWF52148.1 - 0.012 15.8 2.5 0.16 12.2 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 OWF52148.1 - 0.015 15.8 0.2 0.015 15.8 0.2 2.4 2 1 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 OWF52148.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OWF52148.1 - 0.096 12.1 0.0 0.096 12.1 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 OWF52148.1 - 0.15 11.8 2.1 1.2 8.9 0.1 2.5 2 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HEPPP_synt_1 PF07307.11 OWF52148.1 - 0.35 10.4 3.6 2.3 7.8 0.9 2.3 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 T-box PF00907.22 OWF52149.1 - 2.1e-83 279.1 0.1 3.3e-83 278.5 0.1 1.3 1 0 0 1 1 1 1 T-box Morc6_S5 PF17942.1 OWF52150.1 - 2.5e-24 85.9 5.1 1.2e-16 61.0 0.3 2.5 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 OWF52150.1 - 8.7e-21 74.2 0.0 3.8e-20 72.1 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.15 OWF52150.1 - 3.6e-13 49.3 1.2 1.2e-12 47.7 1.2 2.0 1 0 0 1 1 1 1 CW-type Zinc Finger Agenet PF05641.12 OWF52150.1 - 0.0025 18.2 0.6 0.0065 16.9 0.6 1.7 1 0 0 1 1 1 1 Agenet domain HATPase_c PF02518.26 OWF52150.1 - 0.0043 17.5 0.0 0.014 15.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TUDOR_5 PF18359.1 OWF52150.1 - 0.039 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 TetR_C_13 PF16925.5 OWF52150.1 - 0.068 13.1 0.1 0.24 11.4 0.1 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Exonuc_VII_L PF02601.15 OWF52150.1 - 2.9 7.4 16.7 6.1 6.3 4.0 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit UvrD-helicase PF00580.21 OWF52150.1 - 3 7.3 15.7 0.99 8.9 1.0 3.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain TMEM219 PF14940.6 OWF52152.1 - 2.4e-60 204.1 1.5 3e-60 203.7 1.5 1.1 1 0 0 1 1 1 1 Transmembrane 219 SR-25 PF10500.9 OWF52154.1 - 1.4e-43 149.1 72.7 1.5e-41 142.5 26.4 2.3 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 OWF52154.1 - 0.77 8.5 26.3 1.1 8.1 26.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Chorion_2 PF03964.15 OWF52154.1 - 0.99 10.3 11.4 2 9.3 11.4 1.6 1 0 0 1 1 1 0 Chorion family 2 SOBP PF15279.6 OWF52154.1 - 1.2 9.6 25.1 1.5 9.4 25.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF966 PF06136.13 OWF52154.1 - 2.2 7.9 30.6 2.7 7.6 30.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 OWF52154.1 - 2.6 6.2 32.3 3.4 5.8 32.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Dsh_C PF12316.8 OWF52154.1 - 2.8 8.3 28.5 3.9 7.8 28.0 1.5 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal GREB1 PF15782.5 OWF52154.1 - 6 3.8 21.4 6.4 3.8 21.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Draxin PF15550.6 OWF52154.1 - 6.1 6.6 27.8 8.2 6.2 27.8 1.2 1 0 0 1 1 1 0 Draxin Macoilin PF09726.9 OWF52154.1 - 9.4 4.7 28.2 11 4.4 28.2 1.1 1 0 0 1 1 1 0 Macoilin family LRR_9 PF14580.6 OWF52155.1 - 3.3e-12 46.2 0.6 5.6e-07 29.2 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OWF52155.1 - 5.7e-09 35.6 11.2 0.00015 21.5 2.2 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF52155.1 - 1.3e-07 31.8 12.5 0.002 18.5 1.5 4.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF52155.1 - 2.2 9.1 9.2 68 4.6 0.8 4.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF52155.1 - 5.5 7.3 9.0 6.5 7.1 0.5 4.6 5 0 0 5 5 5 0 Leucine Rich repeat ketoacyl-synt PF00109.26 OWF52156.1 - 2.9e-56 190.9 0.1 4.1e-56 190.4 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OWF52156.1 - 4.3e-35 120.3 0.1 9.1e-35 119.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 OWF52156.1 - 2.1e-05 24.0 0.0 4.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 OWF52156.1 - 0.01 16.3 0.1 0.02 15.4 0.1 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension SRR1 PF07985.12 OWF52157.1 - 1.5e-16 60.1 0.7 2.7e-16 59.3 0.1 1.8 2 0 0 2 2 2 1 SRR1 EF-hand_7 PF13499.6 OWF52158.1 - 1.6e-08 34.8 2.6 8.8e-05 22.9 0.9 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF52158.1 - 1.7e-07 30.3 0.4 8.1e-05 21.9 0.1 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 OWF52158.1 - 4.1e-07 29.4 1.8 0.062 13.3 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF52158.1 - 1.9e-05 24.4 3.6 0.023 14.5 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF52158.1 - 0.0087 15.5 0.0 0.027 14.0 0.0 1.9 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.9 OWF52158.1 - 0.022 15.1 0.2 0.045 14.1 0.3 1.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Myosin_head PF00063.21 OWF52160.1 - 2.8e-121 405.9 0.0 2.8e-121 405.9 0.0 3.4 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 OWF52160.1 - 8.1e-12 43.8 159.8 8.1e-12 43.8 159.8 2.7 2 1 1 3 3 3 2 Myosin tail PDZ_6 PF17820.1 OWF52160.1 - 1.4e-07 31.3 0.1 5.9e-07 29.2 0.1 2.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OWF52160.1 - 2.8e-07 30.8 2.3 2.8e-07 30.8 0.2 2.3 2 0 0 2 2 2 1 PDZ domain IQ PF00612.27 OWF52160.1 - 0.02 14.6 1.6 0.13 12.2 0.1 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 OWF52160.1 - 0.033 14.4 1.1 2.1 8.6 0.0 4.2 4 0 0 4 4 4 0 AAA domain QRPTase_C PF01729.19 OWF52161.1 - 1.3e-53 181.3 0.0 1.6e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OWF52161.1 - 9.8e-21 73.6 0.0 2.1e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SM-ATX PF14438.6 OWF52162.1 - 1.2e-19 70.2 0.0 2.9e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 OWF52162.1 - 5.6e-18 65.3 4.6 5.6e-18 65.3 4.6 2.3 2 0 0 2 2 2 1 LsmAD domain LSM14 PF12701.7 OWF52162.1 - 0.00045 20.3 0.0 0.00099 19.2 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain LSM PF01423.22 OWF52162.1 - 0.0042 16.8 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 LSM domain RabGAP-TBC PF00566.18 OWF52163.1 - 2.2e-55 187.7 0.0 2.2e-55 187.7 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain VPR PF00522.18 OWF52163.1 - 0.043 13.8 0.1 0.19 11.8 0.1 2.1 1 1 1 2 2 2 0 VPR/VPX protein HECT PF00632.25 OWF52164.1 - 1.2e-39 136.7 0.0 2.4e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1204 PF06721.11 OWF52164.1 - 0.6 9.5 5.3 0.075 12.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) AbfS_sensor PF18225.1 OWF52165.1 - 0.0043 16.9 0.1 26 4.8 0.0 3.0 3 0 0 3 3 3 3 Sensor histidine kinase (AbfS) sensor domain DUF2335 PF10097.9 OWF52165.1 - 0.065 13.2 8.5 7 6.7 0.4 3.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2335) DNA_pol3_tau_5 PF12170.8 OWF52165.1 - 0.21 11.6 7.8 0.42 10.7 7.7 1.6 1 1 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha TMF_DNA_bd PF12329.8 OWF52165.1 - 0.34 10.9 8.5 2.5 8.1 3.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ion_trans_2 PF07885.16 OWF52167.1 - 1.1e-33 115.0 19.6 1.2e-18 66.8 0.3 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF52167.1 - 7.2e-08 32.0 8.3 6.1e-05 22.4 0.1 2.6 1 1 1 2 2 2 2 Ion transport protein Lig_chan PF00060.26 OWF52167.1 - 0.0041 17.0 0.1 0.0041 17.0 0.1 2.0 2 1 0 2 2 2 1 Ligand-gated ion channel IRK PF01007.20 OWF52167.1 - 0.0089 15.8 0.4 0.052 13.4 0.0 2.4 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain UPF0715 PF17094.5 OWF52167.1 - 0.3 11.6 4.6 0.93 10.1 0.1 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0715) Trypsin PF00089.26 OWF52168.1 - 5.5e-52 176.8 5.9 6.4e-52 176.6 5.9 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OWF52168.1 - 1.5e-06 29.2 0.5 2.2e-06 28.6 0.5 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF52169.1 - 4.2e-31 108.5 3.1 4.6e-31 108.4 3.1 1.0 1 0 0 1 1 1 1 Trypsin Arf PF00025.21 OWF52170.1 - 5e-65 218.2 0.0 6.2e-65 217.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF52170.1 - 5.8e-13 49.1 0.0 8.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF52170.1 - 5.1e-12 45.7 0.0 5.7e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF52170.1 - 3.5e-11 42.9 0.0 4.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF52170.1 - 2.1e-10 40.4 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF52170.1 - 3.8e-09 36.2 0.1 3.9e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF52170.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OWF52170.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Arf PF00025.21 OWF52171.1 - 6.8e-65 217.8 0.0 8.3e-65 217.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF52171.1 - 1.9e-12 47.5 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF52171.1 - 2e-11 43.7 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF52171.1 - 1e-10 41.3 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF52171.1 - 4.4e-10 39.3 0.0 5.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF52171.1 - 4.7e-10 39.2 0.1 2.9e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF52171.1 - 0.00058 19.9 0.0 0.00087 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OWF52171.1 - 0.0054 16.1 0.0 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Tachylectin PF14517.6 OWF52171.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Tachylectin ATP_bind_1 PF03029.17 OWF52171.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.21 OWF52172.1 - 1.4e-64 216.7 0.0 1.7e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF52172.1 - 3.4e-13 49.9 0.0 4.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF52172.1 - 5.6e-12 45.6 0.0 6.2e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF52172.1 - 1.5e-11 44.1 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OWF52172.1 - 2.4e-10 40.1 0.2 8e-07 28.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OWF52172.1 - 3.8e-10 39.5 0.0 4.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF52172.1 - 0.0004 20.4 0.0 0.00075 19.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OWF52172.1 - 0.013 14.8 0.0 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 OWF52172.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OWF52172.1 - 0.04 14.3 0.1 0.28 11.6 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain TFR_dimer PF04253.15 OWF52173.1 - 2.9e-25 88.7 0.0 6.5e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OWF52173.1 - 1.3e-20 73.9 0.0 2.8e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OWF52173.1 - 1.4e-10 41.0 0.0 4.1e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.15 OWF52174.1 - 5.9e-29 100.6 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OWF52174.1 - 3.9e-18 65.9 0.0 2.4e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 OWF52174.1 - 1.3e-10 41.1 0.0 2.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF237 PF03072.14 OWF52174.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF237) P3A PF08727.11 OWF52174.1 - 0.17 11.3 0.0 23 4.5 0.0 2.4 2 0 0 2 2 2 0 Poliovirus 3A protein like Presenilin PF01080.17 OWF52175.1 - 4.4e-166 552.6 3.0 4.4e-166 552.6 3.0 1.4 2 0 0 2 2 2 1 Presenilin Pox_A14 PF05767.12 OWF52175.1 - 0.046 13.9 1.5 0.086 13.0 0.1 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Pox_Ag35 PF03286.14 OWF52175.1 - 2.2 8.0 7.1 0.063 13.1 0.4 1.8 2 1 1 3 3 3 0 Pox virus Ag35 surface protein RGS_DHEX PF18148.1 OWF52176.1 - 4.2e-48 161.6 0.8 1.4e-47 159.9 0.8 1.9 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 OWF52176.1 - 9.6e-32 109.7 0.1 9.6e-32 109.7 0.1 2.2 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 OWF52176.1 - 9.5e-16 57.6 0.0 2.6e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 OWF52176.1 - 7.2e-12 45.1 0.1 2.7e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 GGL domain Piwi PF02171.17 OWF52177.1 - 0.027 13.7 0.5 0.06 12.6 0.1 1.7 2 0 0 2 2 2 0 Piwi domain TT1725 PF18324.1 OWF52177.1 - 0.065 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Hypothetical protein TT1725 Guanylate_kin PF00625.21 OWF52177.1 - 0.069 12.8 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Guanylate kinase CwfJ_C_1 PF04677.15 OWF52178.1 - 3.2e-34 117.4 0.5 8.4e-34 116.1 0.5 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OWF52178.1 - 5.1e-31 107.5 1.4 5.1e-31 107.5 1.4 4.1 5 0 0 5 5 5 1 Protein similar to CwfJ C-terminus 2 Pro_isomerase PF00160.21 OWF52179.1 - 7.1e-51 172.6 0.8 8.3e-51 172.4 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF212 PF02681.14 OWF52180.1 - 0.34 11.1 3.6 3.7 7.7 0.5 2.3 1 1 1 2 2 2 0 Divergent PAP2 family Cu-oxidase_3 PF07732.15 OWF52181.1 - 1e-35 122.3 1.0 2e-35 121.4 1.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 OWF52181.1 - 4.3e-05 23.7 2.5 0.00056 20.1 2.2 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF52181.1 - 0.0039 16.9 2.1 0.049 13.4 2.1 2.4 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OWF52182.1 - 2e-38 131.0 7.0 2e-35 121.4 0.8 3.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF52182.1 - 1.8e-35 121.6 6.2 1.2e-31 109.2 0.2 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF52182.1 - 8.3e-27 94.3 2.5 2.9e-23 82.7 1.8 3.2 2 1 0 2 2 2 2 Multicopper oxidase Clathrin_H_link PF13838.6 OWF52183.1 - 5.5e-13 48.6 10.6 22 5.1 0.0 11.9 5 2 10 15 15 15 13 Clathrin-H-link CRF-BP PF05428.11 OWF52183.1 - 0.012 14.5 11.5 20 3.8 0.0 7.4 1 1 8 9 9 9 0 Corticotropin-releasing factor binding protein (CRF-BP) AKAP7_NLS PF10469.9 OWF52184.1 - 1e-54 185.6 0.0 1.9e-54 184.7 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 OWF52184.1 - 4.4e-10 39.2 1.8 1.1e-09 38.0 1.8 1.7 1 0 0 1 1 1 1 KH domain HVSL PF09749.9 OWF52184.1 - 0.0033 16.9 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein RYDR_ITPR PF01365.21 OWF52185.1 - 1.5e-28 99.6 19.6 6.9e-24 84.4 1.1 5.6 5 0 0 5 5 5 2 RIH domain Ins145_P3_rec PF08709.11 OWF52185.1 - 5.7e-24 84.5 1.9 1e-21 77.1 2.8 2.9 3 0 0 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 OWF52185.1 - 3.2e-21 75.1 1.8 3.2e-21 75.1 1.8 6.2 9 0 0 9 9 9 1 RyR and IP3R Homology associated MIR PF02815.19 OWF52185.1 - 2.5e-14 53.5 6.9 8.3e-12 45.3 0.6 4.1 3 1 0 3 3 3 2 MIR domain Ion_trans PF00520.31 OWF52185.1 - 1.6e-05 24.3 20.1 6.2e-05 22.3 20.1 2.0 1 1 0 1 1 1 1 Ion transport protein AgrB PF04647.15 OWF52185.1 - 1.6 8.0 12.1 0.045 13.1 4.3 2.3 2 0 0 2 2 2 0 Accessory gene regulator B Autophagy_N PF03986.13 OWF52186.1 - 2.6e-53 179.6 1.7 2.6e-53 179.6 1.7 1.5 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OWF52186.1 - 6.7e-21 74.6 1.1 1.6e-20 73.4 1.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OWF52186.1 - 2e-14 52.8 0.9 3.5e-14 52.0 0.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Nucleo_P87 PF07267.11 OWF52186.1 - 0.81 8.5 3.4 1 8.1 3.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SDA1 PF05285.12 OWF52186.1 - 1.1 8.6 13.7 0.88 8.9 12.5 1.4 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 OWF52186.1 - 2.1 6.5 11.2 2.6 6.2 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 OWF52186.1 - 5.1 4.7 5.5 6.6 4.4 5.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CBM_14 PF01607.24 OWF52188.1 - 1.2e-84 278.3 246.6 1.2e-05 25.3 3.8 32.1 28 4 3 31 31 31 30 Chitin binding Peritrophin-A domain zf-C2H2_4 PF13894.6 OWF52188.1 - 1.3 10.1 10.6 15 6.8 0.3 5.7 3 0 0 3 3 3 0 C2H2-type zinc finger Guanylate_cyc PF00211.20 OWF52189.1 - 7.6e-53 178.8 0.0 1.2e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OWF52189.1 - 1.3e-33 116.3 2.6 4.8e-31 107.9 2.6 2.3 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 OWF52189.1 - 4.3e-17 62.6 0.2 8e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 Haem-NO-binding PaO PF08417.12 OWF52189.1 - 0.12 12.5 0.1 3.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Pheophorbide a oxygenase Myelin_MBP PF01669.17 OWF52190.1 - 0.0023 18.6 3.6 42 4.7 0.1 4.7 3 1 2 5 5 5 3 Myelin basic protein Nuf2 PF03800.14 OWF52190.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Nuf2 family Ank_4 PF13637.6 OWF52191.1 - 9.8e-32 108.9 1.5 7.5e-14 51.9 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF52191.1 - 1.3e-24 86.6 0.4 1.7e-17 63.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF52191.1 - 3e-23 81.6 0.1 2.5e-08 34.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF52191.1 - 3.8e-23 80.9 2.7 1.1e-09 38.3 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OWF52191.1 - 4.9e-21 72.6 0.2 8.8e-08 31.8 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat CD20 PF04103.15 OWF52192.1 - 2.8e-05 24.3 4.4 2.8e-05 24.3 4.4 2.2 1 1 1 2 2 2 1 CD20-like family DUF3341 PF11821.8 OWF52192.1 - 0.05 13.3 7.1 1.8 8.2 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Claudin_2 PF13903.6 OWF52192.1 - 2 8.1 9.8 2.1 8.1 2.9 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DAO PF01266.24 OWF52193.1 - 5.5e-24 85.4 0.0 7.1e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OWF52193.1 - 0.0015 17.6 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OWF52193.1 - 0.0085 15.4 0.1 0.021 14.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF52193.1 - 0.01 15.9 0.2 0.64 10.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OWF52193.1 - 0.064 13.5 0.4 0.16 12.2 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OWF52193.1 - 0.12 11.4 0.7 5.5 6.0 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Phlebovirus_G1 PF07243.11 OWF52193.1 - 0.19 10.1 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 CD20 PF04103.15 OWF52194.1 - 0.021 14.9 0.5 0.021 14.9 0.5 2.2 2 1 1 3 3 3 0 CD20-like family DUF3784 PF12650.7 OWF52194.1 - 3.4 7.9 10.1 0.25 11.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF885 PF05960.11 OWF52195.1 - 2.7e-106 357.3 0.0 3.1e-106 357.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) ALC PF17527.2 OWF52195.1 - 0.006 16.3 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 Phage ALC protein CbeA_antitoxin PF06154.11 OWF52195.1 - 0.087 13.4 0.0 0.74 10.4 0.0 2.2 2 0 0 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A TSP_1 PF00090.19 OWF52196.1 - 4.3e-20 71.7 17.4 1.9e-11 44.0 7.3 2.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF52196.1 - 8.2e-09 35.5 11.7 8.2e-09 35.5 11.7 2.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A zf-B_box PF00643.24 OWF52197.1 - 9.3e-07 28.9 22.4 0.0017 18.5 4.8 2.6 2 0 0 2 2 2 2 B-box zinc finger Apolipoprotein PF01442.18 OWF52197.1 - 0.0026 17.7 6.5 0.0045 16.9 6.5 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_13 PF13166.6 OWF52197.1 - 0.0031 16.2 10.0 0.0044 15.7 10.0 1.1 1 0 0 1 1 1 1 AAA domain Exonuc_VII_L PF02601.15 OWF52197.1 - 0.021 14.4 6.3 0.035 13.7 6.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BAR PF03114.18 OWF52197.1 - 0.028 14.1 11.7 0.05 13.2 11.7 1.4 1 0 0 1 1 1 0 BAR domain ATP-synt_B PF00430.18 OWF52197.1 - 0.047 13.8 6.5 0.1 12.7 6.5 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MRP-S31 PF15433.6 OWF52197.1 - 0.065 12.9 8.8 0.099 12.3 8.8 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 LMBR1 PF04791.16 OWF52197.1 - 0.45 9.4 7.9 0.83 8.5 7.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein NleF_casp_inhib PF16809.5 OWF52197.1 - 0.66 9.9 0.0 0.66 9.9 0.0 2.8 2 1 0 2 2 2 0 NleF caspase inhibitor DUF1640 PF07798.11 OWF52197.1 - 1.5 8.8 12.9 2.1 8.3 11.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Tropomyosin_1 PF12718.7 OWF52197.1 - 2.6 8.2 19.3 5.2 7.2 17.7 2.1 2 0 0 2 2 2 0 Tropomyosin like TSP_1 PF00090.19 OWF52199.1 - 4e-15 55.7 28.7 6.4e-09 35.9 10.2 2.9 3 1 0 3 3 3 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF52199.1 - 2.8e-07 30.6 10.0 2.8e-07 30.6 10.0 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A COX2-transmemb PF09125.10 OWF52199.1 - 0.094 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane TSP_1 PF00090.19 OWF52200.1 - 7e-19 67.8 24.6 4.8e-13 49.1 12.5 2.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 OWF52200.1 - 3e-06 27.3 7.6 3e-06 27.3 7.6 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF4524 PF15025.6 OWF52201.1 - 2.5e-43 147.3 0.1 5.6e-43 146.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4524) DUF4520 PF15016.6 OWF52201.1 - 4.8e-27 93.9 0.2 2.6e-24 85.1 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) Mo25 PF08569.11 OWF52202.1 - 3.5e-136 453.9 11.5 3.9e-136 453.7 11.5 1.0 1 0 0 1 1 1 1 Mo25-like Occludin_ELL PF07303.13 OWF52202.1 - 0.0036 18.0 2.5 0.75 10.6 0.1 2.8 2 0 0 2 2 2 2 Occludin homology domain HEAT_2 PF13646.6 OWF52202.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats FMO-like PF00743.19 OWF52203.1 - 3.4e-96 322.8 0.0 4.2e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF52203.1 - 3.8e-24 85.5 0.2 1.5e-18 67.1 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF52203.1 - 3.1e-15 56.2 0.0 1.3e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF52203.1 - 4.5e-10 39.2 0.1 8.7e-07 28.4 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OWF52203.1 - 3.3e-08 33.6 0.1 8e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF52203.1 - 4.8e-07 29.2 0.4 4.8e-07 29.2 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OWF52203.1 - 1.4e-06 28.0 0.3 1.4e-06 28.0 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OWF52203.1 - 1.6e-06 27.7 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 OWF52203.1 - 2.8e-06 27.2 0.4 0.0003 20.5 0.6 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF52203.1 - 2.8e-06 26.8 0.6 7.3e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OWF52203.1 - 1.5e-05 24.4 0.5 3.1e-05 23.4 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF52203.1 - 7.1e-05 21.7 0.2 0.00026 19.8 0.1 1.9 1 1 1 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OWF52203.1 - 0.0017 18.9 4.5 0.059 13.9 0.7 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF52203.1 - 0.0086 15.2 0.5 0.0086 15.2 0.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 OWF52203.1 - 0.011 15.9 0.3 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OWF52203.1 - 0.036 14.0 0.2 1.7 8.6 0.2 2.9 2 1 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OWF52203.1 - 0.082 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OWF52203.1 - 0.95 8.7 6.9 0.068 12.5 0.6 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lipocalin PF00061.23 OWF52204.1 - 7.3e-05 23.0 0.1 0.00018 21.7 0.0 1.6 2 0 0 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF52204.1 - 0.0047 16.8 0.2 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 Triabin Lipocalin PF00061.23 OWF52205.1 - 0.00046 20.4 0.0 0.0013 18.9 0.0 1.7 2 0 0 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 OWF52205.1 - 0.0075 16.1 0.5 0.075 12.9 0.1 2.2 2 1 0 2 2 2 1 Triabin Peptidase_C2 PF00648.21 OWF52206.1 - 3.2e-117 390.8 0.4 4.6e-117 390.3 0.4 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF52206.1 - 3.4e-32 111.6 0.0 7e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 OWF52206.1 - 4.1e-18 65.6 0.9 1.1e-16 60.9 0.0 2.7 2 1 1 3 3 3 1 C2 domain Lectin_C PF00059.21 OWF52207.1 - 2.5e-09 37.8 0.0 2.9e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain HC2 PF07382.11 OWF52208.1 - 4.3e-09 36.7 7.8 5.5e-09 36.4 7.8 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DDE_Tnp_1_3 PF13612.6 OWF52208.1 - 0.0029 17.6 13.5 8.6 6.4 0.4 5.1 1 1 2 3 3 3 3 Transposase DDE domain zf-LITAF-like PF10601.9 OWF52209.1 - 8.1e-23 80.5 7.7 1.2e-22 79.9 7.7 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf_Rg PF17915.1 OWF52209.1 - 0.028 13.8 1.4 5.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Reverse gyrase zinc finger Rubredoxin PF00301.20 OWF52209.1 - 0.042 13.9 1.1 0.64 10.1 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin Sgf11 PF08209.11 OWF52209.1 - 0.046 13.3 2.9 0.87 9.2 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) UPF0547 PF10571.9 OWF52209.1 - 0.062 13.4 2.1 6 7.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.6 OWF52209.1 - 0.07 13.0 3.9 5.5 6.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIB PF13453.6 OWF52209.1 - 0.86 9.0 5.2 11 5.5 0.1 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger SSF PF00474.17 OWF52210.1 - 9.6e-28 97.2 4.2 1.4e-27 96.7 4.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 OWF52211.1 - 1.8e-10 40.2 0.2 2.3e-10 39.9 0.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family MFS_1 PF07690.16 OWF52212.1 - 2.1e-18 66.4 39.0 6e-13 48.4 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 OWF52213.1 - 2.4e-20 72.1 0.2 3.6e-20 71.5 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF52213.1 - 9.1e-07 28.9 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Ten1_2 PF15490.6 OWF52214.1 - 0.042 13.6 15.9 25 4.6 0.3 5.8 1 1 7 8 8 8 0 Telomere-capping, CST complex subunit Bd3614_N PF14442.6 OWF52214.1 - 7.8 6.9 15.8 38 4.7 1.5 5.3 1 1 3 5 5 5 0 Bd3614-like deaminase N-terminal Deltaretro_Tax PF05599.11 OWF52215.1 - 0.0025 18.3 14.0 14 6.3 0.1 6.6 1 1 7 8 8 8 4 Deltaretrovirus Tax protein Ten1_2 PF15490.6 OWF52215.1 - 0.37 10.5 24.4 2.2 8.0 0.8 7.2 1 1 7 8 8 8 0 Telomere-capping, CST complex subunit Astacin PF01400.24 OWF52216.1 - 1.1e-30 106.7 0.0 2.2e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4744 PF15918.5 OWF52217.1 - 0.0052 17.6 10.4 0.052 14.4 3.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4744) SNF PF00209.18 OWF52218.1 - 1.7e-210 700.2 34.2 2.1e-210 699.9 34.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2517 PF10725.9 OWF52218.1 - 0.001 18.8 1.1 0.0035 17.1 0.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2517) Innexin PF00876.18 OWF52220.1 - 3.4e-98 329.2 19.8 4e-98 328.9 19.8 1.0 1 0 0 1 1 1 1 Innexin MRAP PF15183.6 OWF52220.1 - 3.9 7.5 8.5 4.7 7.2 0.9 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Y_phosphatase PF00102.27 OWF52222.1 - 1.1e-77 260.7 0.1 1.8e-77 260.1 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Receptor_IA-2 PF11548.8 OWF52222.1 - 6.7e-09 35.6 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase receptor IA-2 Y_phosphatase3 PF13350.6 OWF52222.1 - 0.032 14.2 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family RESP18 PF14948.6 OWF52222.1 - 0.055 13.8 1.7 0.34 11.2 0.0 2.7 3 0 0 3 3 3 0 RESP18 domain FGAR-AT_linker PF18072.1 OWF52222.1 - 0.057 14.0 0.2 65 4.2 0.1 3.7 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain DSPc PF00782.20 OWF52222.1 - 0.11 12.2 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF5009 PF16401.5 OWF52223.1 - 6e-08 32.5 3.9 6e-08 32.5 3.9 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) DUF1624 PF07786.12 OWF52223.1 - 8.6e-05 22.2 1.8 8.6e-05 22.2 1.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1624) OAD_gamma PF04277.13 OWF52223.1 - 0.0032 18.0 1.2 1.5 9.4 0.0 3.2 3 0 0 3 3 3 1 Oxaloacetate decarboxylase, gamma chain Pex14_N PF04695.13 OWF52223.1 - 0.033 14.8 0.0 9.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OpgC_C PF10129.9 OWF52223.1 - 0.44 9.4 12.5 0.48 9.3 1.0 3.1 2 1 0 2 2 2 0 OpgC protein WH2 PF02205.20 OWF52224.1 - 5e-10 38.9 0.1 1.1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 WH2 motif Kunitz_BPTI PF00014.23 OWF52225.1 - 1.7e-15 57.0 13.8 3.7e-15 55.9 13.8 1.6 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PIF3 PF05006.12 OWF52225.1 - 1.8 8.6 7.9 3.7 7.6 0.4 2.9 3 0 0 3 3 3 0 Per os infectivity factor 3 BPL_N PF09825.9 OWF52225.1 - 4.2 6.4 10.3 5.6 5.9 10.3 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal GIDA PF01134.22 OWF52226.1 - 7e-05 22.1 0.3 1.2 8.1 0.0 2.9 1 1 2 3 3 3 3 Glucose inhibited division protein A EZH2_N PF18601.1 OWF52226.1 - 0.003 17.9 4.7 25 5.3 0.1 4.7 1 1 6 7 7 7 2 EZH2 N-terminal domain DUF4293 PF14126.6 OWF52226.1 - 0.61 10.3 3.1 13 6.0 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) UAA PF08449.11 OWF52227.1 - 2.3e-55 187.9 13.6 2.7e-55 187.7 13.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OWF52227.1 - 4.3e-14 52.9 22.3 8.1e-08 32.5 9.6 2.8 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 OWF52227.1 - 2.2e-09 37.1 4.3 2.4e-06 27.1 0.7 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family SLC35F PF06027.12 OWF52227.1 - 0.00015 21.4 10.3 0.00064 19.3 10.3 1.9 1 1 0 1 1 1 1 Solute carrier family 35 IRK PF01007.20 OWF52227.1 - 0.053 13.3 0.2 0.053 13.3 0.2 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF4293 PF14126.6 OWF52227.1 - 5.1 7.3 8.2 3.3 7.9 0.1 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4293) Wzy_C PF04932.15 OWF52227.1 - 10 5.8 9.7 2 8.0 4.8 2.2 2 1 1 3 3 3 0 O-Antigen ligase Npun_R1517 PF18068.1 OWF52228.1 - 0.095 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Npun R1517 cwf18 PF08315.12 OWF52229.1 - 9.1e-37 126.7 14.6 1.1e-36 126.5 14.6 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF3461 PF11944.8 OWF52229.1 - 0.011 15.9 1.1 0.018 15.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Arg_tRNA_synt_N PF03485.16 OWF52229.1 - 0.023 15.3 1.6 0.27 11.8 0.9 2.2 1 1 1 2 2 2 0 Arginyl tRNA synthetase N terminal domain SIR4_SID PF16991.5 OWF52229.1 - 0.18 11.8 2.2 0.26 11.3 1.8 1.5 1 1 0 1 1 1 0 Sir4 SID domain Phage_min_cap2 PF06152.11 OWF52229.1 - 0.34 9.8 7.4 0.15 10.9 0.5 2.0 2 0 0 2 2 2 0 Phage minor capsid protein 2 BET PF17035.5 OWF52229.1 - 2.4 8.4 6.1 4.1 7.7 0.4 2.6 2 1 1 3 3 3 0 Bromodomain extra-terminal - transcription regulation RHH_1 PF01402.21 OWF52229.1 - 3.2 7.8 6.7 1.8 8.6 2.5 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family 3HCDH_N PF02737.18 OWF52230.1 - 1.9e-44 151.7 0.0 2.6e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OWF52230.1 - 3.8e-08 33.8 0.0 7.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OWF52230.1 - 2.6e-07 30.9 0.0 5.6e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 OWF52230.1 - 0.0015 18.2 0.5 0.0026 17.3 0.5 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 OWF52230.1 - 0.0018 17.9 0.4 0.1 12.1 0.4 2.2 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 OWF52230.1 - 0.0084 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OWF52230.1 - 0.0088 16.0 0.1 0.019 14.9 0.1 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 OWF52230.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 OWF52230.1 - 0.072 12.3 0.0 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 OWF52231.1 - 7.2e-65 215.6 24.7 6.2e-19 68.4 1.0 8.6 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF52231.1 - 8.2e-59 195.3 13.0 2.7e-12 46.9 0.0 11.3 6 5 6 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF52231.1 - 2e-50 162.9 11.0 3e-05 24.1 0.0 17.3 18 0 0 18 18 18 11 Ankyrin repeat Ank_5 PF13857.6 OWF52231.1 - 5.1e-48 160.5 22.0 9.1e-10 38.6 0.0 13.3 7 3 9 16 16 16 11 Ankyrin repeats (many copies) Ank PF00023.30 OWF52231.1 - 7.6e-38 127.3 19.6 8.4e-07 29.2 0.1 16.0 15 1 0 15 15 15 8 Ankyrin repeat Ion_trans PF00520.31 OWF52231.1 - 9.3e-11 41.4 25.8 9.3e-11 41.4 25.8 1.8 1 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 OWF52231.1 - 0.0017 17.1 19.9 0.0034 16.1 19.9 1.6 1 0 0 1 1 1 1 Polycystin cation channel CHDCT2 PF08074.11 OWF52231.1 - 0.021 15.0 0.1 0.068 13.3 0.1 1.9 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF1741 PF08427.10 OWF52231.1 - 0.033 13.8 0.1 0.07 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Ank_2 PF12796.7 OWF52232.1 - 2.3e-54 181.9 24.2 2.1e-14 53.8 0.4 8.0 5 2 2 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF52232.1 - 1.3e-47 159.6 22.5 1e-10 41.9 0.1 11.6 6 3 5 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF52232.1 - 3.8e-47 157.7 20.9 4.9e-09 36.3 0.1 11.2 10 2 3 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF52232.1 - 4.6e-41 134.1 17.1 0.001 19.3 0.0 15.8 16 0 0 16 16 16 10 Ankyrin repeat Ank PF00023.30 OWF52232.1 - 3e-34 116.0 23.6 0.0032 17.9 0.0 13.9 14 0 0 14 14 14 8 Ankyrin repeat Ion_trans PF00520.31 OWF52232.1 - 1.8e-10 40.5 30.0 3e-10 39.7 30.0 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OWF52232.1 - 0.0025 16.6 21.0 0.0038 16.0 21.0 1.3 1 0 0 1 1 1 1 Polycystin cation channel MPC PF03650.13 OWF52233.1 - 1.8e-31 108.5 0.1 2.2e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF2953 PF11167.8 OWF52233.1 - 0.031 14.3 0.1 0.068 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) MFS18 PF17352.2 OWF52234.1 - 0.33 11.3 13.8 46 4.5 0.1 7.3 7 1 0 7 7 7 0 Male Flower Specific protein 18 EGF_CA PF07645.15 OWF52237.1 - 4.1e-66 218.9 517.2 8.8e-08 32.2 3.2 31.0 24 5 6 30 30 30 18 Calcium-binding EGF domain cEGF PF12662.7 OWF52237.1 - 3.2e-58 193.2 287.8 9e-09 35.1 2.2 29.8 29 0 0 29 29 29 23 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF52237.1 - 1e-26 92.9 148.2 3e-08 33.8 11.5 29.0 19 7 10 29 29 29 17 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 OWF52237.1 - 1.2e-13 51.0 51.3 1.4e-08 34.8 8.4 29.5 29 0 0 29 29 29 16 EGF domain NIDO PF06119.14 OWF52237.1 - 2.7e-06 28.2 0.1 2.7e-06 28.2 0.1 3.8 3 0 0 3 3 3 1 Nidogen-like hEGF PF12661.7 OWF52237.1 - 0.008 16.8 2.3 0.008 16.8 2.3 31.6 32 1 0 32 32 32 15 Human growth factor-like EGF PID PF00640.23 OWF52238.1 - 3.6e-25 88.6 0.4 1e-24 87.2 0.4 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SIN1_PH PF16979.5 OWF52238.1 - 0.013 15.8 1.4 0.013 15.8 1.4 2.2 3 0 0 3 3 3 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CREPT PF16566.5 OWF52238.1 - 0.021 15.0 2.2 0.028 14.6 0.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TPPII_N PF12583.8 OWF52239.1 - 0.027 15.1 0.5 0.027 15.1 0.5 3.0 1 1 2 3 3 3 0 Tripeptidyl peptidase II N terminal LRR_5 PF13306.6 OWF52240.1 - 5.4e-06 26.4 20.4 0.00041 20.3 3.3 3.5 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) DUF4768 PF15989.5 OWF52240.1 - 0.013 15.4 21.7 5 7.1 1.3 8.3 1 1 8 10 10 10 0 Domain of unknown function (DUF4768) Methyltransf_2 PF00891.18 OWF52240.1 - 0.016 14.5 3.1 8.6 5.6 0.1 4.3 3 1 2 5 5 5 0 O-methyltransferase domain Colipase-like PF15083.6 OWF52240.1 - 0.096 12.8 34.4 0.061 13.4 5.0 4.6 2 1 2 4 4 4 0 Colipase-like FAM194 PF14977.6 OWF52240.1 - 0.13 11.5 2.7 12 5.2 0.1 3.4 2 1 0 3 3 3 0 FAM194 protein AGO_N PF18236.1 OWF52240.1 - 0.26 11.5 0.6 68 3.7 0.0 4.3 2 1 2 5 5 5 0 Argonaute N domain Colipase-like PF15083.6 OWF52241.1 - 0.0035 17.4 37.8 0.04 14.0 9.9 4.2 1 1 2 4 4 4 4 Colipase-like Methyltransf_2 PF00891.18 OWF52241.1 - 0.0043 16.4 0.8 4.3 6.6 0.0 3.3 2 2 1 3 3 3 2 O-methyltransferase domain Cucumo_coat PF00760.18 OWF52241.1 - 0.043 13.5 0.2 2.3 7.9 0.0 2.5 2 1 0 2 2 2 0 Cucumovirus coat protein LRR_5 PF13306.6 OWF52241.1 - 0.21 11.5 7.3 0.18 11.7 1.3 2.2 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Polysacc_synt_4 PF04669.13 OWF52241.1 - 0.38 10.3 13.8 8.6 5.9 0.2 5.6 1 1 6 8 8 8 0 Polysaccharide biosynthesis DUF4768 PF15989.5 OWF52241.1 - 0.74 9.8 21.3 7.5 6.6 0.4 6.8 1 1 6 8 8 8 0 Domain of unknown function (DUF4768) MFS_1 PF07690.16 OWF52242.1 - 9.4e-16 57.7 19.8 2.6e-06 26.6 0.6 4.2 3 1 1 4 4 4 4 Major Facilitator Superfamily MFS_2 PF13347.6 OWF52242.1 - 2.8e-06 26.1 0.5 2.8e-06 26.1 0.5 4.0 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 OWF52242.1 - 0.49 9.2 18.4 8.7 5.1 2.4 4.4 2 1 0 2 2 2 0 MFS_1 like family Shisa PF13908.6 OWF52243.1 - 0.0076 16.5 0.4 0.014 15.7 0.4 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MAP17 PF15807.5 OWF52243.1 - 0.034 14.4 2.3 0.071 13.3 0.0 2.2 2 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SARAF PF06682.12 OWF52244.1 - 0.00015 21.5 0.1 0.00023 20.9 0.1 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Vpu PF00558.19 OWF52244.1 - 0.00027 20.6 0.2 0.0005 19.8 0.2 1.3 1 0 0 1 1 1 1 Vpu protein DUF2207 PF09972.9 OWF52244.1 - 0.0029 16.4 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 OWF52244.1 - 0.015 15.2 0.0 0.015 15.2 0.0 2.6 2 1 1 3 3 3 0 TMEM154 protein family Shisa PF13908.6 OWF52244.1 - 0.02 15.1 0.2 0.02 15.1 0.2 1.8 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 OWF52244.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Tetraspanin PF00335.20 OWF52244.1 - 0.042 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF4834 PF16118.5 OWF52244.1 - 0.045 14.7 0.8 0.16 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF5305 PF17231.2 OWF52244.1 - 0.052 12.9 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4448 PF14610.6 OWF52244.1 - 0.07 12.9 0.1 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) m04gp34like PF12216.8 OWF52244.1 - 0.086 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Immune evasion protein EphA2_TM PF14575.6 OWF52244.1 - 0.1 13.5 0.0 0.25 12.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 OWF52244.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2615 PF11027.8 OWF52244.1 - 0.11 12.7 0.1 0.34 11.1 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) Tad PF13400.6 OWF52244.1 - 0.22 11.9 2.4 0.35 11.2 2.4 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Vpu PF00558.19 OWF52245.1 - 5.5e-05 22.9 1.0 9.8e-05 22.0 1.0 1.3 1 0 0 1 1 1 1 Vpu protein Sigma_reg_N PF13800.6 OWF52245.1 - 0.0059 16.9 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 Sigma factor regulator N-terminal Phage_holin_3_6 PF07332.11 OWF52245.1 - 0.052 13.6 0.7 0.087 12.9 0.7 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ASFV_J13L PF05568.11 OWF52245.1 - 0.064 13.0 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Cadherin_C_2 PF16492.5 OWF52245.1 - 0.077 13.7 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal SARAF PF06682.12 OWF52245.1 - 0.081 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TMEM154 PF15102.6 OWF52245.1 - 0.11 12.4 4.9 2.2 8.2 1.4 2.5 2 0 0 2 2 2 0 TMEM154 protein family DUF4381 PF14316.6 OWF52245.1 - 0.18 12.0 0.2 0.31 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) bZIP_2 PF07716.15 OWF52247.1 - 1.5e-15 57.0 12.5 2.8e-15 56.1 12.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF52247.1 - 3.8e-05 23.7 7.9 3.8e-05 23.7 7.9 1.8 2 0 0 2 2 2 1 bZIP transcription factor DUF3621 PF12285.8 OWF52247.1 - 0.081 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) Macoilin PF09726.9 OWF52247.1 - 2 6.9 14.2 0.66 8.5 2.0 2.2 2 0 0 2 2 2 0 Macoilin family CBM_14 PF01607.24 OWF52248.1 - 1.9e-16 59.9 17.7 5.1e-09 36.2 4.5 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF52249.1 - 1.1e-13 51.1 17.9 2.5e-10 40.3 7.7 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF52250.1 - 1.8e-17 63.2 16.7 1.8e-11 44.0 6.7 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Acyltransf_C PF16076.5 OWF52250.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Acyltransferase C-terminus CBM_14 PF01607.24 OWF52252.1 - 1.7e-17 63.3 20.3 1.7e-10 40.9 9.7 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain GP70 PF17429.2 OWF52252.1 - 0.081 12.8 0.5 0.36 10.7 0.1 2.2 3 0 0 3 3 3 0 Gene product 70 ABC_tran PF00005.27 OWF52253.1 - 5.1e-29 101.5 0.0 8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OWF52253.1 - 2.2e-20 73.0 8.6 2.8e-20 72.6 8.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 OWF52253.1 - 5.9e-07 29.6 0.4 0.0026 17.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OWF52253.1 - 0.00018 21.5 0.3 0.00032 20.6 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 OWF52253.1 - 0.0014 17.7 0.5 0.0024 17.0 0.5 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 OWF52253.1 - 0.0096 15.5 0.2 0.02 14.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OWF52253.1 - 0.028 14.5 0.5 0.12 12.4 0.5 2.1 1 1 0 1 1 1 0 Dynamin family Rad17 PF03215.15 OWF52253.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 OWF52253.1 - 0.048 13.8 0.2 0.087 12.9 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 OWF52253.1 - 0.055 13.9 0.2 0.59 10.6 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF52253.1 - 0.059 13.7 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 OWF52253.1 - 0.066 12.9 0.2 0.14 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OWF52253.1 - 0.068 13.7 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OWF52253.1 - 0.071 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OWF52253.1 - 0.1 13.1 0.1 0.63 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF52253.1 - 0.13 11.8 0.2 0.25 10.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OWF52253.1 - 0.15 12.5 0.1 0.36 11.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 OWF52254.1 - 8.3e-29 100.9 0.0 1.5e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OWF52254.1 - 8.4e-26 90.7 14.3 1.3e-25 90.1 14.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 OWF52254.1 - 1.2e-06 28.6 0.1 0.0011 18.8 0.0 2.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OWF52254.1 - 0.00021 21.3 0.1 0.00047 20.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 OWF52254.1 - 0.00038 19.6 0.3 0.0007 18.7 0.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 OWF52254.1 - 0.0011 18.6 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OWF52254.1 - 0.005 16.9 0.1 0.011 15.8 0.1 1.6 1 1 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 OWF52254.1 - 0.015 15.7 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 OWF52254.1 - 0.02 14.6 0.1 0.043 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OWF52254.1 - 0.027 14.8 0.1 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OWF52254.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 OWF52254.1 - 0.07 13.2 0.5 0.41 10.7 0.3 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OWF52254.1 - 0.079 13.5 0.3 0.32 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF52254.1 - 0.082 12.4 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 OWF52254.1 - 0.083 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 OWF52254.1 - 0.14 12.1 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 OWF52254.1 - 0.15 12.5 0.3 1.6 9.1 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OWF52254.1 - 0.16 11.7 0.8 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AMP-binding PF00501.28 OWF52255.1 - 1.7e-66 224.6 0.0 2.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF52255.1 - 7.2e-06 26.9 0.0 1.4e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IL34 PF15036.6 OWF52255.1 - 0.15 12.1 0.3 15 5.6 0.0 2.6 3 0 0 3 3 3 0 Interleukin 34 AMP-binding PF00501.28 OWF52256.1 - 5.4e-10 38.4 0.1 6.6e-10 38.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF52256.1 - 0.077 14.0 0.3 0.13 13.2 0.3 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Peptidase_C48 PF02902.19 OWF52257.1 - 1.9e-11 44.2 0.3 5.7e-11 42.7 0.3 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF2862 PF11061.8 OWF52257.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) DUF1003 PF06210.11 OWF52258.1 - 1 9.5 7.3 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Neur_chan_LBD PF02931.23 OWF52259.1 - 1e-08 34.9 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52259.1 - 3e-05 24.2 3.7 4.3e-05 23.7 3.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4519 PF15012.6 OWF52259.1 - 0.23 11.7 3.3 0.36 11.0 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF792 PF05632.11 OWF52260.1 - 2.7 7.8 11.1 3.7 7.4 5.6 2.0 1 1 1 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF792) ABC1 PF03109.16 OWF52261.1 - 1.5e-35 121.9 0.0 2.7e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 OWF52261.1 - 0.00055 19.4 0.2 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 OWF52261.1 - 0.023 14.6 0.1 0.27 11.1 0.2 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family SKIP_SNW PF02731.15 OWF52262.1 - 6.2e-73 243.7 4.6 6.2e-73 243.7 4.6 2.0 2 0 0 2 2 2 1 SKIP/SNW domain BHD_1 PF10403.9 OWF52263.1 - 0.099 12.5 0.0 10 6.1 0.0 3.0 2 1 1 3 3 3 0 Rad4 beta-hairpin domain 1 Albumin_I PF08027.11 OWF52263.1 - 0.63 9.7 7.1 4.6 6.9 1.0 3.3 2 2 0 2 2 2 0 Albumin I chain b MIT PF04212.18 OWF52264.1 - 0.16 12.1 10.3 91 3.2 0.0 6.9 4 1 4 8 8 8 0 MIT (microtubule interacting and transport) domain Extensin_2 PF04554.13 OWF52264.1 - 0.75 9.9 9.0 2.7 8.1 3.7 2.3 1 1 1 2 2 2 0 Extensin-like region Colicin_immun PF09204.10 OWF52264.1 - 5.1 7.7 16.5 6.8 7.3 1.0 4.3 1 1 3 4 4 4 0 Bacterial self-protective colicin-like immunity Proho_convert PF12177.8 OWF52265.1 - 0.00042 20.2 0.0 24 5.0 0.0 7.6 3 2 6 9 9 9 1 Prohormone convertase enzyme MIT PF04212.18 OWF52266.1 - 0.013 15.6 9.9 43 4.3 0.1 6.7 3 2 5 8 8 8 0 MIT (microtubule interacting and transport) domain Proho_convert PF12177.8 OWF52266.1 - 0.22 11.6 0.0 24 5.0 0.0 3.6 2 2 1 4 4 4 0 Prohormone convertase enzyme Colicin_immun PF09204.10 OWF52266.1 - 0.63 10.6 8.3 8 7.1 2.0 3.3 1 1 3 4 4 4 0 Bacterial self-protective colicin-like immunity Sec23_BS PF08033.12 OWF52266.1 - 0.88 10.3 8.7 30 5.4 0.2 3.8 2 2 1 3 3 3 0 Sec23/Sec24 beta-sandwich domain zf-RING_UBOX PF13445.6 OWF52268.1 - 2.8e-10 40.1 8.1 2.8e-10 40.1 8.1 3.6 4 1 1 5 5 5 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF52268.1 - 1.9e-07 31.3 9.7 1.9e-07 31.3 9.7 3.6 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF52268.1 - 2.5e-07 30.7 10.1 2.5e-07 30.7 10.1 3.5 3 2 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF52268.1 - 4.7e-07 29.5 5.7 4.7e-07 29.5 5.7 4.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF52268.1 - 5.6e-07 29.3 10.6 5.6e-07 29.3 10.6 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF52268.1 - 6.4e-06 26.2 4.5 6.4e-06 26.2 4.5 4.3 4 2 0 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF52268.1 - 1.5e-05 24.8 10.0 1.5e-05 24.8 10.0 3.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF52268.1 - 2.6e-05 24.1 9.0 2.6e-05 24.1 9.0 3.6 3 1 0 3 3 3 1 zinc-RING finger domain DUF2387 PF09526.10 OWF52268.1 - 0.013 15.6 2.7 0.013 15.6 2.7 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) LRAT PF04970.13 OWF52269.1 - 6e-20 71.8 1.4 8.7e-12 45.5 0.1 2.3 1 1 1 2 2 2 2 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 OWF52269.1 - 0.016 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 NlpC/P60 family Calici_PP_N PF08405.11 OWF52269.1 - 0.066 12.0 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal UL45 PF05473.12 OWF52270.1 - 0.031 13.9 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like NapE PF06796.11 OWF52271.1 - 0.63 9.6 0.1 0.63 9.6 0.1 2.1 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Transcrip_act PF04949.13 OWF52274.1 - 9.7e-07 28.8 18.6 9.7e-07 28.8 18.6 1.9 2 0 0 2 2 2 1 Transcriptional activator HTH_Tnp_Tc5 PF03221.16 OWF52274.1 - 3.1e-06 27.1 0.0 6.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_24 PF13412.6 OWF52274.1 - 0.00015 21.3 0.0 0.00035 20.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 OWF52274.1 - 0.00036 20.2 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 OWF52274.1 - 0.00051 19.9 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 MarR family CENP-B_N PF04218.13 OWF52274.1 - 0.0033 17.0 0.6 0.013 15.2 0.6 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 OWF52274.1 - 0.0035 17.3 0.2 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain UPF0175 PF03683.13 OWF52274.1 - 0.013 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) MarR PF01047.22 OWF52274.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 OWF52274.1 - 0.028 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 OWF52274.1 - 0.05 13.7 0.0 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_4 PF13613.6 OWF52274.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_11 PF08279.12 OWF52274.1 - 0.062 13.2 0.1 0.25 11.3 0.1 2.0 1 0 0 1 1 1 0 HTH domain MFS18 PF17352.2 OWF52274.1 - 0.07 13.5 10.1 0.29 11.5 10.1 2.0 1 0 0 1 1 1 0 Male Flower Specific protein 18 Sigma70_r4 PF04545.16 OWF52274.1 - 0.07 12.7 0.1 0.22 11.1 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 OWF52274.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 OWF52274.1 - 0.18 11.8 1.4 0.74 9.8 0.0 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain DUF1013 PF06242.11 OWF52274.1 - 7.8 6.5 10.8 0.12 12.4 0.3 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1013) EMC3_TMCO1 PF01956.16 OWF52275.1 - 2.2e-37 128.4 0.4 2.5e-37 128.2 0.4 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DivIC PF04977.15 OWF52275.1 - 0.063 13.1 0.6 0.063 13.1 0.6 2.3 1 1 1 2 2 2 0 Septum formation initiator XhlA PF10779.9 OWF52275.1 - 0.076 13.2 4.0 0.29 11.4 3.7 2.1 1 1 0 1 1 1 0 Haemolysin XhlA DUF1090 PF06476.12 OWF52275.1 - 0.41 10.8 11.9 0.27 11.4 10.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Cons_hypoth95 PF03602.15 OWF52276.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 META PF03724.16 OWF52276.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 META domain cNMP_binding PF00027.29 OWF52277.1 - 1.3e-23 82.9 0.2 7.6e-12 45.1 0.0 4.3 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain HetR_C PF18460.1 OWF52277.1 - 0.046 13.6 0.1 0.53 10.3 0.0 2.8 2 1 1 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain DnaJ PF00226.31 OWF52278.1 - 3.1e-20 72.1 0.6 8.8e-20 70.6 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain zf-B_box PF00643.24 OWF52279.1 - 0.00076 19.6 11.1 0.00076 19.6 11.1 2.9 2 1 0 2 2 2 1 B-box zinc finger WD40 PF00400.32 OWF52281.1 - 0.00035 21.3 3.2 0.12 13.2 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat C2 PF00168.30 OWF52282.1 - 3.7e-56 187.8 0.8 1.4e-20 73.5 0.0 3.5 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 OWF52282.1 - 2.4e-53 180.3 0.4 5.2e-53 179.2 0.4 1.6 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DUF4283 PF14111.6 OWF52282.1 - 0.15 11.6 0.3 3.1 7.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) zinc_ribbon_2 PF13240.6 OWF52283.1 - 5.1 7.0 6.7 8 6.3 0.4 3.0 3 0 0 3 3 3 0 zinc-ribbon domain 7tm_1 PF00001.21 OWF52285.1 - 3.2e-16 59.5 13.6 3.9e-16 59.2 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FAM193_C PF15914.5 OWF52285.1 - 0.13 12.1 0.2 0.13 12.1 0.2 2.0 2 0 0 2 2 2 0 FAM193 family C-terminal SHP PF03579.13 OWF52285.1 - 0.14 12.1 0.2 0.14 12.1 0.2 2.3 1 1 1 2 2 2 0 Small hydrophobic protein MbeD_MobD PF04899.12 OWF52286.1 - 2.8e-20 72.2 31.2 0.41 10.8 0.2 11.0 1 1 10 11 11 11 11 MbeD/MobD like OstA PF03968.14 OWF52286.1 - 1.5e-13 50.9 45.1 0.3 11.3 0.7 9.5 1 1 8 9 9 9 9 OstA-like protein LPP PF04728.13 OWF52286.1 - 1.5e-11 44.5 66.0 0.4 11.1 1.7 11.3 1 1 14 15 15 15 14 Lipoprotein leucine-zipper Prefoldin PF02996.17 OWF52286.1 - 3.7e-11 43.0 0.0 11 6.0 0.0 7.1 1 1 4 7 7 7 0 Prefoldin subunit DASH_Dam1 PF08653.10 OWF52286.1 - 1.3e-08 34.5 35.0 14 5.6 0.2 11.8 1 1 12 13 13 13 0 DASH complex subunit Dam1 SlyX PF04102.12 OWF52286.1 - 7.3e-07 29.7 0.1 21 5.8 0.0 5.9 1 1 5 6 6 6 0 SlyX Rbsn PF11464.8 OWF52286.1 - 1.4e-06 28.0 34.2 39 4.1 0.1 14.2 1 1 14 17 17 17 0 Rabenosyn Rab binding domain NPV_P10 PF05531.12 OWF52286.1 - 6.2e-06 26.6 68.6 1.8e+04 -47.1 68.6 8.3 1 1 0 1 1 0 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 OWF52286.1 - 6.8e-06 26.5 1.3 7.2 7.2 0.3 5.5 1 1 1 2 2 2 1 Protein of unknown function DUF16 DUF948 PF06103.11 OWF52286.1 - 0.00027 21.1 60.9 1.8 8.9 7.3 5.5 1 1 4 5 5 5 2 Bacterial protein of unknown function (DUF948) PAAR_motif PF05488.13 OWF52286.1 - 0.0003 20.9 8.6 55 4.0 0.1 5.8 1 1 2 3 3 3 0 PAAR motif ATG16 PF08614.11 OWF52286.1 - 0.00053 20.3 0.0 2 8.6 0.0 2.9 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 OWF52286.1 - 0.001 19.1 28.9 2 8.5 3.3 4.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Laminin_I PF06008.14 OWF52286.1 - 0.0032 17.2 7.5 0.9 9.2 0.6 3.4 1 1 2 3 3 3 2 Laminin Domain I GOLGA2L5 PF15070.6 OWF52286.1 - 0.0074 15.0 0.0 18 3.8 0.0 3.4 1 1 3 4 4 4 0 Putative golgin subfamily A member 2-like protein 5 CaMKII_AD PF08332.10 OWF52286.1 - 0.15 12.2 25.6 1e+02 3.1 0.4 9.3 1 1 9 10 10 10 0 Calcium/calmodulin dependent protein kinase II association domain Flu_B_M2 PF04772.12 OWF52286.1 - 0.17 12.2 42.7 49 4.2 1.2 11.5 1 1 2 3 3 2 0 Influenza B matrix protein 2 (BM2) FlaC_arch PF05377.11 OWF52286.1 - 0.21 12.0 49.0 57 4.2 1.0 10.0 1 1 3 4 4 3 0 Flagella accessory protein C (FlaC) DUF4988 PF16378.5 OWF52286.1 - 0.24 11.1 42.8 1.8e+04 -29.2 42.8 7.1 1 1 0 1 1 0 0 Domain of unknown function Ribonuc_P_40 PF08584.11 OWF52286.1 - 0.37 10.0 50.0 8.9 5.5 0.6 9.5 1 1 10 11 11 11 0 Ribonuclease P 40kDa (Rpp40) subunit BDV_P24 PF06595.11 OWF52286.1 - 4.7 7.1 25.5 33 4.3 0.9 5.5 1 1 3 4 4 4 0 Borna disease virus P24 protein RTBV_P46 PF06216.11 OWF52286.1 - 8.5 5.1 10.5 16 4.2 1.8 3.2 1 1 2 3 3 3 0 Rice tungro bacilliform virus P46 protein TSKS PF15358.6 OWF52286.1 - 8.9 4.6 15.0 13 4.0 0.7 3.6 1 1 4 5 5 5 0 Testis-specific serine kinase substrate Pentapeptide_4 PF13599.6 OWF52287.1 - 1.9e-06 27.9 0.0 15 5.8 0.0 6.1 2 1 5 7 7 7 2 Pentapeptide repeats (9 copies) HC2 PF07382.11 OWF52287.1 - 2.6e-06 27.7 106.7 0.04 14.0 6.5 6.1 2 2 4 6 6 6 5 Histone H1-like nucleoprotein HC2 PMG PF05287.12 OWF52287.1 - 0.0064 16.6 7.1 0.0064 16.6 7.1 5.8 1 1 4 6 6 6 2 PMG protein Keratin_B2_2 PF13885.6 OWF52287.1 - 0.084 12.8 18.9 0.33 11.0 0.4 5.2 3 2 1 5 5 5 0 Keratin, high sulfur B2 protein Methyltransf_FA PF12248.8 OWF52287.1 - 0.43 10.9 25.6 0.51 10.7 0.7 7.1 2 2 4 7 7 7 0 Farnesoic acid 0-methyl transferase UPF0086 PF01868.16 OWF52287.1 - 0.57 10.1 39.2 61 3.6 1.7 10.7 2 2 2 4 4 4 0 Domain of unknown function UPF0086 HC2 PF07382.11 OWF52288.1 - 0.0084 16.2 16.7 0.011 15.8 16.7 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Ribonucleas_3_3 PF14622.6 OWF52289.1 - 3.1e-43 147.0 0.6 2.6e-21 76.1 0.0 3.4 2 1 1 3 3 3 3 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OWF52289.1 - 7.2e-42 142.3 0.1 2e-19 70.1 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 OWF52289.1 - 1.2e-09 38.8 0.4 5.1e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif IMUP PF15761.5 OWF52289.1 - 0.0084 16.8 6.1 0.0084 16.8 6.1 4.1 3 1 0 4 4 4 1 Immortalisation up-regulated protein Bactofilin PF04519.13 OWF52290.1 - 0.0002 21.6 15.8 0.00069 19.9 15.3 1.8 1 1 1 2 2 2 2 Polymer-forming cytoskeletal Chorion_1 PF01723.16 OWF52290.1 - 0.0064 16.5 15.7 0.17 11.8 8.1 2.2 1 1 1 2 2 2 2 Chorion protein Drf_FH1 PF06346.12 OWF52290.1 - 0.066 12.9 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 CRAM_rpt PF07016.11 OWF52290.1 - 0.17 11.7 21.4 0.61 9.9 0.5 5.1 1 1 2 4 4 4 0 Cysteine-rich acidic integral membrane protein precursor PhnG PF06754.12 OWF52290.1 - 8.8 6.3 6.8 14 5.7 1.4 2.3 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnG VWA PF00092.28 OWF52291.1 - 2.1e-41 142.1 4.2 3e-39 135.1 2.8 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF52291.1 - 5.9e-15 55.8 0.1 1.3e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF52291.1 - 3e-07 30.5 0.0 7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OWF52291.1 - 0.00087 18.7 0.1 0.0017 17.8 0.1 1.5 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein Herpes_env PF01673.18 OWF52291.1 - 0.021 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Peptidase_C2 PF00648.21 OWF52292.1 - 9.3e-103 343.3 0.2 1.2e-102 342.9 0.2 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF52292.1 - 1.3e-23 83.8 0.0 3.1e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 Calpain large subunit, domain III DUF1654 PF07867.11 OWF52292.1 - 0.29 10.9 2.8 0.9 9.3 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) TSP_1 PF00090.19 OWF52293.1 - 1.7e-30 105.0 124.5 1e-05 25.6 3.8 13.0 12 1 0 12 12 12 9 Thrombospondin type 1 domain I-set PF07679.16 OWF52293.1 - 3.3e-08 33.5 0.0 9.2e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF52293.1 - 1.5e-07 31.9 0.0 5.5e-07 30.1 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain PLAC PF08686.11 OWF52293.1 - 3.4e-06 27.7 9.2 3.4e-06 27.7 9.2 3.6 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Ig_2 PF13895.6 OWF52293.1 - 6.6e-06 26.4 0.0 3.5e-05 24.0 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain DENN PF02141.21 OWF52294.1 - 1.9e-56 191.0 3.2 1.9e-56 191.0 3.2 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 OWF52294.1 - 4.2e-17 62.6 0.2 1.2e-16 61.2 0.2 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OWF52294.1 - 2.1e-14 53.2 4.0 5.2e-14 52.0 4.0 1.8 1 0 0 1 1 1 1 dDENN domain DUF2464 PF10240.9 OWF52294.1 - 3.9e-07 29.9 0.7 1.6e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 Multivesicular body subunit 12 PPR_2 PF13041.6 OWF52294.1 - 4.9e-07 29.8 0.3 0.00017 21.7 0.0 2.9 1 1 1 2 2 2 2 PPR repeat family PPR_long PF17177.4 OWF52294.1 - 0.0083 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 OWF52294.1 - 0.012 15.7 0.2 0.3 11.2 0.1 2.6 1 1 1 2 2 2 0 Pentatricopeptide repeat domain PPR PF01535.20 OWF52294.1 - 0.13 12.5 0.4 0.9 9.9 0.0 2.6 2 0 0 2 2 2 0 PPR repeat Peptidase_M14 PF00246.24 OWF52295.1 - 1.5e-14 54.5 0.0 3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OWF52295.1 - 4.5e-12 46.3 2.8 5.9e-12 45.9 0.6 2.3 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 OWF52295.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF4523 PF15023.6 OWF52295.1 - 0.14 12.0 1.4 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) CLN6 PF15156.6 OWF52296.1 - 4.7e-127 423.1 16.1 5.9e-127 422.7 16.1 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 PXT1 PF15214.6 OWF52296.1 - 0.35 11.2 1.7 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 DUF3959 PF13105.6 OWF52296.1 - 0.36 10.3 2.5 0.5 9.8 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) zf-RING_UBOX PF13445.6 OWF52297.1 - 3.3e-09 36.6 1.8 3.3e-09 36.6 1.8 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 OWF52297.1 - 1.9e-07 31.1 7.6 1.9e-07 31.1 7.6 2.9 3 0 0 3 3 3 1 B-box zinc finger zf-RING_5 PF14634.6 OWF52297.1 - 5.8e-07 29.4 8.2 5.8e-07 29.4 8.2 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF52297.1 - 1.1e-05 25.7 11.6 1.1e-05 25.7 11.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OWF52297.1 - 2e-05 24.4 8.6 2e-05 24.4 8.6 3.0 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF52297.1 - 0.00017 21.3 3.8 0.00017 21.3 3.8 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF52297.1 - 0.00059 19.5 4.9 0.0015 18.2 4.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 OWF52297.1 - 0.0031 17.4 3.0 0.0031 17.4 3.0 3.0 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF52297.1 - 0.0055 16.5 9.5 0.0055 16.5 9.5 3.0 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OWF52297.1 - 0.0057 16.8 1.8 0.0057 16.8 1.8 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING DUF745 PF05335.13 OWF52297.1 - 0.0091 15.7 6.1 0.016 14.9 6.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 OWF52297.1 - 0.022 14.4 4.9 0.035 13.7 4.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2616 PF11077.8 OWF52297.1 - 0.31 10.7 7.4 0.64 9.7 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Fzo_mitofusin PF04799.13 OWF52297.1 - 0.99 8.9 3.2 2.7 7.5 2.7 2.0 1 1 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 OWF52297.1 - 2.5 7.2 4.7 3.8 6.7 4.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF2180 PF09947.9 OWF52297.1 - 3 7.9 8.2 0.19 11.7 1.8 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Spc7 PF08317.11 OWF52297.1 - 6.1 5.6 20.1 0.099 11.5 13.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-RING_5 PF14634.6 OWF52298.1 - 2.1e-06 27.6 4.9 2.1e-06 27.6 4.9 2.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-B_box PF00643.24 OWF52298.1 - 6.3e-06 26.2 13.7 6.3e-06 26.2 13.7 3.2 3 0 0 3 3 3 1 B-box zinc finger zf-RING_UBOX PF13445.6 OWF52298.1 - 2.3e-05 24.3 4.4 2.3e-05 24.3 4.4 3.0 3 0 0 3 3 1 1 RING-type zinc-finger DUF5082 PF16888.5 OWF52298.1 - 0.00034 20.9 10.3 0.026 14.8 0.9 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) zf-C3HC4 PF00097.25 OWF52298.1 - 0.00085 19.1 4.4 0.00085 19.1 4.4 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OWF52298.1 - 0.0028 17.4 1.8 0.0028 17.4 1.8 2.9 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OWF52298.1 - 0.014 15.7 8.1 0.014 15.7 8.1 3.2 3 1 0 3 3 1 0 Ring finger domain Spc7 PF08317.11 OWF52298.1 - 0.045 12.6 14.7 0.05 12.5 13.1 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein HMMR_N PF15905.5 OWF52298.1 - 0.053 13.0 16.2 0.09 12.2 16.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal zf-FPG_IleRS PF06827.14 OWF52298.1 - 0.087 12.7 4.7 4.6 7.2 1.3 3.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Exonuc_VII_L PF02601.15 OWF52298.1 - 0.095 12.3 2.3 0.13 11.8 2.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Leu_zip PF15294.6 OWF52298.1 - 0.16 11.4 17.9 0.77 9.2 9.7 2.4 2 1 1 3 3 3 0 Leucine zipper Apolipoprotein PF01442.18 OWF52298.1 - 0.24 11.3 9.7 0.46 10.3 9.7 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain AAA_lid_9 PF17871.1 OWF52298.1 - 0.41 10.6 10.5 0.72 9.8 0.8 2.4 2 0 0 2 2 2 0 AAA lid domain Muted PF14942.6 OWF52298.1 - 0.47 10.8 17.5 2.9 8.2 4.8 2.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein FliD_C PF07195.12 OWF52298.1 - 0.67 9.3 10.9 0.34 10.3 0.8 3.1 2 1 2 4 4 4 0 Flagellar hook-associated protein 2 C-terminus SKA2 PF16740.5 OWF52298.1 - 0.74 9.6 12.0 2.2 8.1 4.6 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 OWF52298.1 - 0.92 10.0 14.3 0.46 11.0 4.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Spectrin PF00435.21 OWF52298.1 - 1.1 9.8 9.3 2.6 8.6 1.4 2.5 2 0 0 2 2 2 0 Spectrin repeat DUF5327 PF17261.2 OWF52298.1 - 2.7 8.8 6.8 0.54 11.0 2.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF724 PF05266.14 OWF52298.1 - 4.8 7.0 15.8 0.17 11.7 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CorA PF01544.18 OWF52298.1 - 5.4 6.3 6.7 10 5.3 6.5 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Ax_dynein_light PF10211.9 OWF52298.1 - 7.2 6.5 19.3 9.7 6.1 10.8 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain Syntaxin-6_N PF09177.11 OWF52298.1 - 8.3 7.0 13.4 2.9 8.5 4.9 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ING PF12998.7 OWF52298.1 - 9.1 6.9 10.3 12 6.5 7.3 2.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ELL PF10390.9 OWF52299.1 - 3.3e-75 253.2 0.0 8.2e-75 251.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 OWF52299.1 - 4.8e-28 97.8 12.5 1.6e-27 96.2 12.5 2.0 1 0 0 1 1 1 1 Occludin homology domain Y_phosphatase PF00102.27 OWF52300.1 - 1.3e-67 227.8 0.1 1.3e-67 227.8 0.1 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 OWF52300.1 - 0.022 14.6 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF52300.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family YTH PF04146.15 OWF52301.1 - 3.7e-38 131.1 6.0 1.2e-35 122.9 6.0 3.2 1 1 0 1 1 1 1 YT521-B-like domain HA2 PF04408.23 OWF52301.1 - 6.2e-21 74.7 0.0 2.2e-20 72.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OWF52301.1 - 9.3e-15 54.9 0.0 2.3e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OWF52301.1 - 1.4e-12 47.8 0.2 3.4e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold R3H PF01424.22 OWF52301.1 - 1.6e-10 40.8 0.1 5.7e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 R3H domain DEAD PF00270.29 OWF52301.1 - 7.3e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.7 OWF52301.1 - 0.00021 21.8 0.0 0.00062 20.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF913 PF06025.12 OWF52301.1 - 0.00026 20.1 0.4 0.0006 18.9 0.4 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) T2SSE PF00437.20 OWF52301.1 - 0.0055 15.8 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 OWF52301.1 - 0.012 15.7 0.0 0.14 12.2 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OWF52301.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OWF52301.1 - 0.017 14.5 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 OWF52301.1 - 0.028 14.9 1.6 0.29 11.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 OWF52301.1 - 0.087 13.1 0.2 0.42 10.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain PHD PF00628.29 OWF52302.1 - 6.1e-08 32.4 7.5 8.4e-08 32.0 7.5 1.2 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 OWF52302.1 - 0.012 15.3 3.8 0.016 14.8 3.8 1.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain RAG2_PHD PF13341.6 OWF52302.1 - 0.018 15.1 0.9 0.033 14.2 0.9 1.5 1 1 0 1 1 1 0 RAG2 PHD domain PHD_2 PF13831.6 OWF52302.1 - 0.022 14.3 3.1 0.022 14.3 3.1 2.8 1 1 1 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 OWF52302.1 - 0.075 13.3 3.3 0.094 13.0 3.3 1.1 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 OWF52302.1 - 1.8 8.6 9.1 0.13 12.2 3.6 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 TTL PF03133.15 OWF52303.1 - 5.4e-85 285.1 0.6 1.2e-84 284.0 0.6 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF52303.1 - 1.4e-05 24.4 0.5 0.023 13.9 0.0 3.1 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF52303.1 - 0.00015 21.1 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OWF52303.1 - 0.017 15.1 0.0 0.072 13.1 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain SHIPPO-rpt PF07004.12 OWF52306.1 - 2.7e-06 28.0 6.4 1.8 9.6 0.5 4.6 4 0 0 4 4 4 4 Sperm-tail PG-rich repeat Paf1 PF03985.13 OWF52307.1 - 1.4e-142 475.6 24.7 4.9e-142 473.9 24.7 1.7 1 1 0 1 1 1 1 Paf1 RSRP PF17069.5 OWF52307.1 - 0.0038 16.8 34.7 0.0097 15.5 34.7 1.7 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 PKD_3 PF16820.5 OWF52307.1 - 0.057 13.2 1.3 0.74 9.6 0.4 2.4 2 0 0 2 2 2 0 PKD-like domain Profilin PF00235.19 OWF52308.1 - 1.1e-06 28.9 0.0 1.3e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Profilin SAM_4 PF18017.1 OWF52309.1 - 4.8e-28 96.9 0.0 8.8e-28 96.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5577 PF17740.1 OWF52309.1 - 6.2e-23 81.9 14.1 1.6e-21 77.3 11.6 2.5 1 1 1 2 2 2 2 Family of unknown function (DUF5577) SAM_2 PF07647.17 OWF52309.1 - 0.0043 17.1 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF52309.1 - 0.029 14.8 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PDZ PF00595.24 OWF52310.1 - 1.6e-18 66.8 0.6 2.3e-18 66.3 0.6 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF52310.1 - 1.5e-07 31.6 0.2 1.9e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF52310.1 - 9.9e-06 25.3 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain ATP-synt_Z PF16594.5 OWF52310.1 - 0.043 13.3 0.1 0.059 12.9 0.1 1.2 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated DUF4448 PF14610.6 OWF52310.1 - 0.18 11.6 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DCX PF03607.17 OWF52311.1 - 1.1e-15 57.4 0.2 3.3e-12 46.3 0.1 2.5 2 0 0 2 2 2 2 Doublecortin GRIP PF01465.20 OWF52312.1 - 6.8e-16 57.9 0.1 2.2e-15 56.3 0.1 2.0 1 0 0 1 1 1 1 GRIP domain BLOC1_2 PF10046.9 OWF52312.1 - 0.0047 17.2 2.5 0.0047 17.2 2.5 7.7 5 3 3 8 8 8 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 OWF52312.1 - 0.0054 17.0 25.9 0.0054 17.0 25.9 6.1 2 1 4 6 6 6 3 Autophagy protein 16 (ATG16) SHE3 PF17078.5 OWF52312.1 - 0.011 15.5 10.4 0.011 15.5 10.4 5.8 4 1 1 5 5 5 0 SWI5-dependent HO expression protein 3 Thioredoxin_8 PF13905.6 OWF52312.1 - 0.62 10.4 3.5 0.88 9.9 0.6 2.9 2 0 0 2 2 2 0 Thioredoxin-like BRX_N PF13713.6 OWF52312.1 - 3.2 7.6 6.4 11 5.9 0.4 2.8 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain NUC153 PF08159.12 OWF52313.1 - 5.5e-14 51.7 1.3 1.6e-10 40.6 0.0 3.1 2 0 0 2 2 2 2 NUC153 domain tRNA-synt_2b PF00587.25 OWF52314.1 - 6.4e-29 101.2 0.0 1.5e-28 100.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BTB PF00651.31 OWF52315.1 - 3.6e-20 72.2 0.3 8.5e-20 71.0 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF52315.1 - 3.3e-14 52.8 3.4 1.6e-12 47.4 1.5 2.5 1 1 1 2 2 2 2 BTB And C-terminal Kelch BTB PF00651.31 OWF52316.1 - 1.2e-24 86.6 0.4 6.6e-23 81.1 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 OWF52316.1 - 9.7e-20 70.6 0.1 2.6e-19 69.2 0.1 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 OWF52316.1 - 3.3e-19 69.3 0.0 1.7e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 F5/8 type C domain CBFD_NFYB_HMF PF00808.23 OWF52317.1 - 5.7e-19 68.2 1.1 9.9e-19 67.4 1.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OWF52317.1 - 4.3e-06 27.1 0.3 4.3e-06 27.1 0.3 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF4407 PF14362.6 OWF52317.1 - 0.024 14.0 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_Ag35 PF03286.14 OWF52317.1 - 0.067 13.0 13.5 0.13 12.0 13.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.22 OWF52317.1 - 0.07 12.3 2.4 0.089 12.0 2.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.6 OWF52317.1 - 0.33 11.5 15.8 0.49 10.9 15.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein FAM176 PF14851.6 OWF52317.1 - 0.66 9.6 7.2 1.4 8.6 7.2 1.6 1 0 0 1 1 1 0 FAM176 family PGA2 PF07543.12 OWF52317.1 - 0.7 9.9 10.8 1.2 9.1 10.8 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Tim54 PF11711.8 OWF52317.1 - 0.81 8.4 8.2 1.3 7.7 8.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FancD2 PF14631.6 OWF52317.1 - 1.9 5.8 6.3 2.3 5.5 6.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MCM_bind PF09739.9 OWF52317.1 - 4 5.8 9.3 5.1 5.4 9.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Hid1 PF12722.7 OWF52317.1 - 6.9 4.7 7.1 7.4 4.6 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5427 PF10310.9 OWF52317.1 - 7.3 5.4 15.2 9.7 5.0 15.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CobT PF06213.12 OWF52317.1 - 9.1 5.6 15.0 19 4.6 14.9 1.5 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT CBF PF03914.17 OWF52318.1 - 4.4e-49 166.8 0.1 4.4e-49 166.8 0.1 4.0 4 0 0 4 4 4 1 CBF/Mak21 family Cnd1 PF12717.7 OWF52318.1 - 0.0018 18.4 2.8 0.0072 16.4 0.7 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 PAS_11 PF14598.6 OWF52319.1 - 6.7e-23 81.0 0.2 1.2e-17 64.1 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 OWF52319.1 - 3.9e-20 71.9 0.0 3.1e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OWF52319.1 - 5.6e-07 29.6 0.0 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OWF52319.1 - 0.0002 21.5 0.1 0.095 13.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 OWF52319.1 - 0.00032 21.3 0.0 0.0015 19.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold HLH PF00010.26 OWF52319.1 - 0.0044 16.9 0.6 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 OWF52319.1 - 0.0062 16.8 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold CARD PF00619.21 OWF52319.1 - 0.037 14.1 0.1 0.097 12.7 0.1 1.7 1 0 0 1 1 1 0 Caspase recruitment domain Pkinase PF00069.25 OWF52320.1 - 3.2e-76 256.2 3.1 8e-36 123.8 0.1 4.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OWF52320.1 - 2.2e-42 145.1 1.2 8.1e-16 58.1 0.0 4.5 3 1 1 4 4 4 4 Protein tyrosine kinase RWD PF05773.22 OWF52320.1 - 1.2e-18 67.5 0.1 4.5e-18 65.6 0.1 2.2 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 OWF52320.1 - 1.6e-16 60.5 0.0 3.5e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 OWF52320.1 - 8e-15 55.1 3.3 9.6e-15 54.8 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Kinase-like PF14531.6 OWF52320.1 - 0.0002 20.8 0.1 0.3 10.4 0.1 3.3 3 0 0 3 3 3 2 Kinase-like DUF1744 PF08490.12 OWF52320.1 - 0.039 12.5 0.0 2.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1744) HGTP_anticodon PF03129.20 OWF52320.1 - 0.04 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Anticodon binding domain APH PF01636.23 OWF52320.1 - 0.077 12.9 0.0 0.077 12.9 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 OWF52320.1 - 0.53 9.6 5.8 0.34 10.2 0.3 3.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1068 PF06364.12 OWF52322.1 - 0.011 15.6 3.6 0.022 14.6 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Miff PF05644.11 OWF52322.1 - 0.52 9.9 10.0 0.061 13.0 4.1 2.1 1 1 1 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff zf-met PF12874.7 OWF52323.1 - 5.8e-06 26.5 0.3 1.5e-05 25.2 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SH3_9 PF14604.6 OWF52323.1 - 0.0027 17.5 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain zf-C2H2_jaz PF12171.8 OWF52323.1 - 0.003 17.8 0.4 0.0063 16.8 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OWF52323.1 - 0.0049 17.6 0.2 0.021 15.6 0.2 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger hSH3 PF14603.6 OWF52323.1 - 0.025 15.0 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_3 PF08239.11 OWF52323.1 - 0.055 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_1 PF00018.28 OWF52323.1 - 0.081 12.5 0.1 0.28 10.8 0.1 2.0 1 1 0 1 1 1 0 SH3 domain Na_H_Exchanger PF00999.21 OWF52324.1 - 1.3e-79 267.8 38.5 7.8e-79 265.2 38.5 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2830 PF11125.8 OWF52324.1 - 0.035 14.1 1.0 0.96 9.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2830) DUF4293 PF14126.6 OWF52324.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF3948 PF13134.6 OWF52324.1 - 4.2 7.1 6.1 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) RRM_1 PF00076.22 OWF52325.1 - 0.00018 21.3 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OWF52325.1 - 0.003 17.6 0.6 0.012 15.6 0.1 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 OWF52325.1 - 0.0064 16.3 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif OstA PF03968.14 OWF52326.1 - 0.00028 21.1 4.1 0.34 11.1 2.1 3.1 1 1 1 2 2 2 2 OstA-like protein DUF4097 PF13349.6 OWF52326.1 - 0.0034 16.8 9.0 0.006 16.0 9.0 1.4 1 1 0 1 1 1 1 Putative adhesin DUF4397 PF14344.6 OWF52326.1 - 0.0061 17.3 1.8 0.014 16.2 1.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4397) DUF3739 PF12545.8 OWF52326.1 - 0.013 16.0 12.1 0.092 13.2 5.7 2.2 1 1 1 2 2 2 0 Filamentous haemagglutinin family outer membrane protein DUF3540 PF12059.8 OWF52326.1 - 0.03 14.2 0.3 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) STN PF07660.14 OWF52326.1 - 0.038 13.8 3.7 19 5.1 0.1 4.1 1 1 1 2 2 2 0 Secretin and TonB N terminus short domain Metallophos PF00149.28 OWF52327.1 - 2e-13 51.3 1.6 2.7e-13 50.9 1.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OWF52327.1 - 6.3e-11 42.7 0.2 2.7e-09 37.4 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Fibrinogen_C PF00147.18 OWF52328.1 - 7.5e-55 186.1 5.5 8.7e-55 185.9 5.5 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF5348 PF17295.2 OWF52328.1 - 0.017 15.0 0.3 5.7 6.9 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5348) Fibrinogen_C PF00147.18 OWF52329.1 - 3.4e-50 170.9 5.0 4.2e-50 170.6 5.0 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 OWF52330.1 - 8.2e-56 189.3 2.8 1e-55 188.9 2.8 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_1 PF00024.26 OWF52330.1 - 0.00014 21.8 0.7 0.00025 20.9 0.7 1.4 1 0 0 1 1 1 1 PAN domain Sulfatase PF00884.23 OWF52331.1 - 1.2e-62 212.1 0.9 1.5e-62 211.8 0.9 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF52331.1 - 1.9e-06 27.7 0.1 3e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF52332.1 - 4.7e-68 229.8 0.6 6.4e-68 229.4 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF52332.1 - 9.3e-05 22.2 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OWF52332.1 - 0.0044 17.8 0.2 0.018 15.8 0.2 2.0 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase NHL PF01436.21 OWF52333.1 - 0.0007 19.5 0.1 3 8.0 0.2 3.7 3 1 0 3 3 3 2 NHL repeat Sulfatase PF00884.23 OWF52334.1 - 5.5e-49 167.2 0.1 8.3e-49 166.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OWF52334.1 - 0.013 16.2 0.2 0.059 14.1 0.2 2.0 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OWF52334.1 - 0.045 13.3 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase SLBP_RNA_bind PF15247.6 OWF52335.1 - 1.7 8.8 10.1 7.5 6.7 0.3 3.5 2 2 2 5 5 5 0 Histone RNA hairpin-binding protein RNA-binding domain Plant_tran PF04827.14 OWF52335.1 - 4.3 6.9 7.6 9.3 5.8 0.7 2.1 1 1 1 2 2 2 0 Plant transposon protein SSF PF00474.17 OWF52336.1 - 6.6e-46 157.0 23.2 8.6e-46 156.6 23.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Imm17 PF15562.6 OWF52337.1 - 0.031 14.1 0.3 0.066 13.1 0.3 1.5 1 0 0 1 1 1 0 Immunity protein 17 DUF2681 PF10883.8 OWF52337.1 - 0.033 14.6 0.1 0.059 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) I-set PF07679.16 OWF52338.1 - 0.00098 19.1 0.4 3 8.0 0.1 3.2 2 1 0 2 2 2 2 Immunoglobulin I-set domain Lep_receptor_Ig PF06328.11 OWF52338.1 - 0.038 14.0 0.2 0.17 11.9 0.0 2.3 2 1 0 2 2 2 0 Ig-like C2-type domain EF-hand_6 PF13405.6 OWF52339.1 - 2.2e-21 73.9 4.0 1.4e-06 27.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OWF52339.1 - 1.6e-20 71.0 7.0 5.9e-07 28.6 0.0 4.6 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF52339.1 - 2.4e-16 60.0 6.4 8.9e-10 38.9 0.8 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF52339.1 - 3.2e-15 54.9 3.5 8e-05 22.0 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF52339.1 - 1e-12 47.7 7.5 6.6e-10 38.7 0.8 3.5 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF52339.1 - 0.0035 17.7 1.1 4.4 7.7 0.2 3.0 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PMBR PF09373.10 OWF52339.1 - 0.089 13.0 0.3 5.3 7.4 0.0 2.8 3 0 0 3 3 3 0 Pseudomurein-binding repeat SSF PF00474.17 OWF52340.1 - 1.3e-05 24.3 1.4 1.5e-05 24.0 1.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4022 PF13214.6 OWF52340.1 - 0.024 14.9 0.8 0.1 12.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) CCB1 PF12046.8 OWF52340.1 - 0.083 12.2 0.1 0.13 11.6 0.1 1.4 1 1 0 1 1 1 0 Cofactor assembly of complex C subunit B IFT81_CH PF18383.1 OWF52341.1 - 1e-49 167.9 1.3 1e-49 167.9 1.3 3.2 4 0 0 4 4 4 1 Intraflagellar transport 81 calponin homology domain LPP PF04728.13 OWF52341.1 - 0.029 14.8 9.7 3.7 8.0 1.0 4.9 5 0 0 5 5 5 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 OWF52341.1 - 0.033 14.3 1.0 0.033 14.3 1.0 6.4 5 1 1 6 6 6 0 TolA binding protein trimerisation Spc7 PF08317.11 OWF52341.1 - 0.041 12.8 60.1 0.021 13.8 10.3 4.8 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF3800 PF12686.7 OWF52341.1 - 0.26 11.9 5.2 75 4.0 5.2 3.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF948 PF06103.11 OWF52341.1 - 0.89 9.9 10.5 0.77 10.1 0.2 4.6 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) SPC25 PF06703.11 OWF52342.1 - 1.6e-41 141.8 0.1 2.2e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) TssN PF17555.2 OWF52342.1 - 0.014 14.8 1.4 0.023 14.1 1.4 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN ThiS-like PF14453.6 OWF52342.1 - 0.076 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 ThiS-like ubiquitin Choline_transpo PF04515.12 OWF52342.1 - 0.63 9.2 4.2 0.33 10.1 1.0 1.8 2 0 0 2 2 2 0 Plasma-membrane choline transporter BRAP2 PF07576.12 OWF52343.1 - 1.3e-07 31.7 13.6 14 6.0 0.0 10.1 1 1 9 12 12 12 4 BRCA1-associated protein 2 VID27_N PF17748.1 OWF52343.1 - 0.00043 20.2 17.4 12 5.7 0.0 9.1 7 3 0 10 10 10 3 VID27 N-terminal region DUF3877 PF12993.7 OWF52343.1 - 0.042 13.7 48.0 6 6.7 0.2 13.9 2 2 13 17 17 17 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4590 PF15257.6 OWF52343.1 - 2.2 8.2 27.0 99 2.9 0.2 10.0 1 1 10 15 15 15 0 Domain of unknown function (DUF4590) 7tm_1 PF00001.21 OWF52345.1 - 4.7e-09 35.9 6.5 6e-09 35.6 6.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF52345.1 - 8.7e-07 28.8 6.7 1.4e-06 28.2 6.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF52345.1 - 0.00066 19.1 3.7 0.0011 18.5 3.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PhaG_MnhG_YufB PF03334.14 OWF52345.1 - 0.023 14.9 2.9 0.057 13.7 2.9 1.7 1 1 0 1 1 1 0 Na+/H+ antiporter subunit 7TM_GPCR_Srbc PF10316.9 OWF52345.1 - 0.069 12.6 4.2 0.092 12.2 4.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc RB_A PF01858.17 OWF52346.1 - 7.8e-68 228.2 0.7 7.8e-68 228.2 0.7 2.8 2 1 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 OWF52346.1 - 1e-36 125.9 8.7 3.2e-35 121.0 2.9 3.2 3 0 0 3 3 3 2 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 OWF52346.1 - 8.5e-19 67.5 0.8 1.9e-17 63.1 0.4 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) Rb_C PF08934.10 OWF52346.1 - 1e-11 44.9 1.4 1e-11 44.9 1.4 2.3 2 0 0 2 2 2 1 Rb C-terminal domain MFS_1 PF07690.16 OWF52347.1 - 8.3e-30 103.9 30.6 8.3e-30 103.9 30.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF52347.1 - 0.023 13.6 27.1 0.29 9.9 4.6 3.3 2 1 1 3 3 3 0 Sugar (and other) transporter BIR PF00653.21 OWF52348.1 - 5.7e-36 123.0 5.8 3.2e-17 63.0 0.2 3.0 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF52348.1 - 3.4e-09 36.4 15.8 3.4e-09 36.4 15.8 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF52348.1 - 0.12 12.2 14.5 0.31 11.0 14.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF52348.1 - 0.13 12.6 16.2 0.53 10.7 16.2 2.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OWF52348.1 - 1.1 9.3 19.2 0.31 11.0 15.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain ATP-grasp_2 PF08442.10 OWF52349.1 - 9.9e-59 198.3 0.0 1.9e-58 197.4 0.0 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 OWF52349.1 - 1.6e-26 92.9 1.5 3.6e-26 91.8 1.5 1.6 1 0 0 1 1 1 1 CoA-ligase GARS_A PF01071.19 OWF52349.1 - 0.0041 16.9 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 OWF52349.1 - 0.036 14.3 0.2 0.068 13.4 0.2 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Succ_CoA_lig PF13607.6 OWF52349.1 - 0.046 13.5 0.4 1 9.1 0.1 2.5 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 OWF52349.1 - 0.084 12.3 0.2 0.21 11.0 0.0 1.9 2 1 0 2 2 2 0 ATP-grasp domain DUF3943 PF13084.6 OWF52350.1 - 0.0027 17.5 29.8 1.2 9.1 5.0 3.7 1 1 3 4 4 4 4 Domain of unknown function (DUF3943) adh_short PF00106.25 OWF52352.1 - 7.8e-44 149.5 0.0 1.1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF52352.1 - 4.1e-28 98.5 0.0 5.9e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OWF52352.1 - 6.2e-10 38.9 0.0 8.8e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OWF52352.1 - 1.3e-07 31.7 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF52352.1 - 0.16 11.4 0.1 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Caprin-1_dimer PF18293.1 OWF52354.1 - 1.4e-38 132.0 1.0 1.4e-38 132.0 1.0 2.4 2 0 0 2 2 2 1 Caprin-1 dimerization domain IBV_3B PF03622.13 OWF52354.1 - 0.14 12.3 0.1 0.38 10.9 0.1 1.7 1 0 0 1 1 1 0 IBV 3B protein Mob1_phocein PF03637.17 OWF52355.1 - 1.9e-56 190.7 2.8 2.4e-56 190.4 2.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family SIR2 PF02146.17 OWF52356.1 - 1.6e-50 171.4 0.0 2.7e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Trypsin_2 PF13365.6 OWF52357.1 - 2.7e-24 86.8 0.8 6.3e-21 75.8 1.1 2.9 3 0 0 3 3 3 2 Trypsin-like peptidase domain GLTSCR1 PF15249.6 OWF52358.1 - 1.4e-26 92.9 2.5 8.4e-26 90.4 2.5 2.5 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Plasmodium_HRP PF05403.11 OWF52359.1 - 1.1e-12 48.3 67.1 0.00034 20.5 5.3 7.0 1 1 6 7 7 7 6 Plasmodium histidine-rich protein (HRPII/III) CUT PF02376.15 OWF52360.1 - 3.9e-32 110.2 0.9 7.3e-32 109.4 0.5 1.7 2 0 0 2 2 2 1 CUT domain Homeodomain PF00046.29 OWF52360.1 - 1.6e-11 43.9 0.5 3.7e-11 42.7 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF52360.1 - 5.5e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Questin_oxidase PF14027.6 OWF52361.1 - 2.3e-34 119.5 0.0 2.8e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Questin_oxidase PF14027.6 OWF52362.1 - 4.3e-38 131.7 0.0 5.1e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like p450 PF00067.22 OWF52363.1 - 1.1e-87 294.7 0.0 1.5e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tropomyosin_1 PF12718.7 OWF52364.1 - 0.00014 22.0 7.9 7.1 6.8 0.1 6.1 2 2 7 9 9 9 2 Tropomyosin like Tropomyosin PF00261.20 OWF52364.1 - 0.0017 17.8 0.0 0.4 10.0 0.0 4.0 2 2 3 5 5 5 1 Tropomyosin zinc_ribbon_4 PF13717.6 OWF52364.1 - 0.033 14.1 2.6 2.5e+02 1.7 0.1 7.6 3 0 0 3 3 3 0 zinc-ribbon domain DUF745 PF05335.13 OWF52364.1 - 0.066 12.9 0.7 54 3.4 0.0 4.9 2 2 4 7 7 7 0 Protein of unknown function (DUF745) ATP-synt_B PF00430.18 OWF52364.1 - 1.6 8.9 5.2 1.7 8.7 0.1 3.7 4 1 0 4 4 4 0 ATP synthase B/B' CF(0) Homeodomain PF00046.29 OWF52365.1 - 3e-24 84.6 6.8 5.3e-24 83.8 6.8 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 OWF52365.1 - 6.7e-09 35.3 2.4 1.7e-08 34.0 2.4 1.8 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF52365.1 - 0.00086 19.2 0.2 0.002 18.0 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain FAM176 PF14851.6 OWF52365.1 - 3.3 7.4 6.0 5.6 6.6 6.0 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 OWF52365.1 - 5.3 5.2 8.2 6.7 4.9 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Frag1 PF10277.9 OWF52366.1 - 4.2e-47 160.5 5.4 4.8e-47 160.3 5.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family F-box PF00646.33 OWF52368.1 - 0.002 18.0 0.0 0.0061 16.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 OWF52368.1 - 0.014 15.8 2.5 0.068 13.5 0.0 3.2 5 0 0 5 5 5 0 PRANC domain F-box-like PF12937.7 OWF52368.1 - 0.021 14.7 0.2 0.22 11.4 0.0 2.9 3 0 0 3 3 3 0 F-box-like PAXNEB PF05625.11 OWF52369.1 - 1.2e-108 363.6 0.0 1.5e-108 363.3 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Y_phosphatase PF00102.27 OWF52370.1 - 3.3e-73 246.1 0.0 8.2e-73 244.8 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Orthoreo_P10 PF07204.11 OWF52370.1 - 0.00098 19.0 0.5 0.0024 17.8 0.5 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 DSPc PF00782.20 OWF52370.1 - 0.0016 18.3 0.2 0.0037 17.1 0.2 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF52370.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Thyroglobulin_1 PF00086.18 OWF52371.1 - 8.3e-12 44.6 14.2 1.5e-07 31.0 4.1 3.1 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat Fascin PF06268.13 OWF52371.1 - 9e-05 22.7 0.2 0.56 10.4 0.1 3.2 1 1 2 3 3 3 2 Fascin domain IGFBP PF00219.18 OWF52371.1 - 0.00012 22.6 10.2 0.00012 22.6 10.2 3.1 3 1 0 3 3 3 1 Insulin-like growth factor binding protein CheW PF01584.19 OWF52371.1 - 0.13 11.9 0.0 6.4 6.4 0.0 2.2 2 0 0 2 2 2 0 CheW-like domain Herpes_UL92 PF03048.14 OWF52371.1 - 0.68 9.7 5.8 1.2 8.9 1.1 2.2 2 0 0 2 2 2 0 UL92 family Thyroglobulin_1 PF00086.18 OWF52372.1 - 7e-12 44.9 22.9 1.4e-07 31.0 4.3 3.3 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat IGFBP PF00219.18 OWF52372.1 - 0.00019 22.0 9.0 0.00019 22.0 9.0 3.1 3 1 0 3 3 3 1 Insulin-like growth factor binding protein Fascin PF06268.13 OWF52372.1 - 0.00035 20.8 0.2 3.4 7.9 0.1 3.3 1 1 2 3 3 3 2 Fascin domain Herpes_UL92 PF03048.14 OWF52372.1 - 2.4 7.9 6.6 4.4 7.0 0.7 2.4 2 0 0 2 2 2 0 UL92 family Thyroglobulin_1 PF00086.18 OWF52373.1 - 6.8e-21 73.7 23.0 1.9e-07 30.6 1.7 3.7 3 1 0 3 3 3 3 Thyroglobulin type-1 repeat IGFBP PF00219.18 OWF52373.1 - 9.6e-05 23.0 10.3 9.6e-05 23.0 10.3 4.2 5 0 0 5 5 5 1 Insulin-like growth factor binding protein Nbl1_Borealin_N PF10444.9 OWF52373.1 - 0.051 13.2 1.8 9.2 6.0 0.1 2.6 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal TetR_C_17 PF17922.1 OWF52373.1 - 0.059 13.5 0.0 8.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain C5HCH PF17982.1 OWF52373.1 - 0.086 13.0 15.4 5.1 7.3 1.1 4.1 3 0 0 3 3 3 0 NSD Cys-His rich domain Bac_chlorC PF02043.17 OWF52373.1 - 0.17 11.9 0.0 36 4.5 0.0 2.6 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Glyco_transf_11 PF01531.16 OWF52374.1 - 2.6e-29 102.4 0.5 3.3e-29 102.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 Glyco_transf_11 PF01531.16 OWF52375.1 - 3.7e-27 95.3 0.5 4.2e-27 95.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Glyco_hydro_20 PF00728.22 OWF52376.1 - 2.3e-81 273.9 0.8 4.7e-81 272.9 0.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OWF52376.1 - 8.2e-17 62.1 0.0 2.5e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OWF52376.1 - 4e-08 34.1 0.0 8.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Say1_Mug180 PF10340.9 OWF52376.1 - 0.038 12.9 0.2 0.06 12.2 0.2 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_transf_54 PF04666.13 OWF52377.1 - 5.9e-74 248.5 0.9 1e-73 247.8 0.9 1.3 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region OB_NTP_bind PF07717.16 OWF52378.1 - 2.4e-16 59.8 0.0 7.5e-16 58.3 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OWF52378.1 - 2.3e-15 56.8 1.6 4.4e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OWF52378.1 - 2.4e-15 56.8 0.0 6.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF52378.1 - 8.4e-13 48.5 0.0 2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF52378.1 - 1.3e-05 25.5 0.1 4.5e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain dsRBD2 PF17842.1 OWF52378.1 - 0.0027 17.9 0.2 0.0027 17.9 0.2 2.2 2 0 0 2 2 1 1 Double-stranded RNA binding domain 2 AAA_19 PF13245.6 OWF52378.1 - 0.0055 17.1 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain dsrm PF00035.26 OWF52378.1 - 0.006 17.3 0.0 0.031 15.0 0.0 2.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif ATPase PF06745.13 OWF52378.1 - 0.01 15.2 2.3 0.021 14.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 OWF52378.1 - 0.036 13.8 0.3 0.34 10.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain OmdA PF13376.6 OWF52378.1 - 0.11 12.5 0.0 0.56 10.3 0.0 2.2 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated ABC_tran PF00005.27 OWF52378.1 - 0.44 11.0 0.0 0.44 11.0 0.0 2.9 3 0 0 3 3 3 0 ABC transporter JAKMIP_CC3 PF16034.5 OWF52379.1 - 0.1 12.5 2.8 0.066 13.1 0.8 1.7 1 1 1 2 2 2 0 JAKMIP CC3 domain Mnd1 PF03962.15 OWF52379.1 - 0.19 12.1 0.1 0.41 11.0 0.1 1.5 1 0 0 1 1 1 0 Mnd1 HTH domain NAP PF00956.18 OWF52380.1 - 2.3e-107 358.2 10.7 3.4e-107 357.6 10.7 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Raf1_N PF18578.1 OWF52381.1 - 0.00023 21.6 1.2 31 5.1 0.0 4.9 1 1 6 7 7 7 1 Rubisco accumulation factor 1 alpha helical domain FA PF08736.11 OWF52381.1 - 0.11 12.6 2.2 8.6 6.5 0.0 4.1 3 1 1 4 4 4 0 FERM adjacent (FA) ART-PolyVal PF18760.1 OWF52381.1 - 0.42 11.6 2.8 70 4.5 2.8 3.5 1 1 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins TAD2 PF18521.1 OWF52381.1 - 0.53 10.3 26.6 38 4.5 0.1 8.1 6 3 2 8 8 8 0 Transactivation domain 2 Fz PF01392.22 OWF52382.1 - 2.6e-31 108.5 7.6 2.6e-31 108.5 7.6 2.1 2 0 0 2 2 2 1 Fz domain NTR PF01759.21 OWF52382.1 - 2e-13 50.1 0.5 5.8e-13 48.6 0.1 2.0 1 1 1 2 2 2 1 UNC-6/NTR/C345C module SYS1 PF09801.9 OWF52383.1 - 0.0083 16.3 0.1 0.013 15.6 0.1 1.4 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network MoCF_biosynth PF00994.24 OWF52384.1 - 2.3e-28 98.7 0.0 3.8e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 OWF52384.1 - 3.6e-26 92.3 0.0 7.4e-19 68.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family LMWPc PF01451.21 OWF52385.1 - 4.2e-41 140.6 0.0 4.8e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Methyltransf_FA PF12248.8 OWF52386.1 - 4.9e-39 132.8 0.2 6.5e-19 68.1 0.0 2.3 2 0 0 2 2 2 2 Farnesoic acid 0-methyl transferase zf-C4 PF00105.18 OWF52387.1 - 7.8e-26 90.3 10.6 7.8e-26 90.3 10.6 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF52387.1 - 3e-14 53.1 1.0 1.5e-13 50.8 1.0 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF52388.1 - 7.2e-27 93.6 11.0 7.2e-27 93.6 11.0 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF52388.1 - 6.2e-14 52.1 1.2 3.6e-13 49.6 1.2 2.0 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Neur_chan_LBD PF02931.23 OWF52389.1 - 8.1e-19 67.9 0.5 1.4e-18 67.1 0.5 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52389.1 - 8.4e-09 35.8 0.4 8.4e-09 35.8 0.4 2.0 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.16 OWF52390.1 - 2.7e-09 37.4 1.2 2.7e-09 37.4 1.2 2.1 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF52390.1 - 0.024 14.1 0.2 0.05 13.0 0.0 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel ligand binding domain DUF1704 PF08014.11 OWF52391.1 - 7.3e-12 45.0 0.1 4.6e-11 42.4 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1704) Robl_LC7 PF03259.17 OWF52392.1 - 2.3e-24 85.0 0.0 2.5e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 OWF52392.1 - 0.00027 20.8 0.0 0.00037 20.3 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 OWF52392.1 - 0.14 12.6 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain C1q PF00386.21 OWF52394.1 - 4.1e-20 72.3 0.4 7.9e-20 71.4 0.4 1.5 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF52394.1 - 0.0017 18.3 2.3 0.002 18.0 0.8 1.8 2 0 0 2 2 2 1 BclA C-terminal domain ZapB PF06005.12 OWF52394.1 - 0.0026 18.2 2.1 0.004 17.6 2.1 1.3 1 0 0 1 1 1 1 Cell division protein ZapB Laminin_G_1 PF00054.23 OWF52394.1 - 0.0037 17.5 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain CASP_C PF08172.12 OWF52394.1 - 0.0037 16.6 1.1 0.0049 16.3 1.1 1.2 1 0 0 1 1 1 1 CASP C terminal TNF PF00229.18 OWF52394.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family CtIP_N PF10482.9 OWF52394.1 - 0.14 12.2 3.2 0.25 11.4 3.2 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain GIT_CC PF16559.5 OWF52394.1 - 0.23 11.4 2.4 0.45 10.4 2.4 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor RICH PF05062.12 OWF52394.1 - 1.1 9.7 5.6 0.28 11.6 1.6 1.9 2 0 0 2 2 2 0 RICH domain C1q PF00386.21 OWF52395.1 - 3.2e-13 50.0 0.0 4.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF52395.1 - 0.0044 16.9 0.9 0.0063 16.4 0.9 1.2 1 0 0 1 1 1 1 BclA C-terminal domain Peptidase_M30 PF10460.9 OWF52395.1 - 0.042 12.8 0.1 0.08 11.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase M30 PapD-like PF14874.6 OWF52395.1 - 0.066 13.4 0.2 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Flagellar-associated PapD-like Neur_chan_LBD PF02931.23 OWF52396.1 - 2.4e-17 63.1 0.2 3.9e-17 62.4 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52396.1 - 7.6e-15 55.6 0.0 1.3e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF52397.1 - 2.3e-28 99.2 0.9 4.3e-28 98.2 0.9 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52397.1 - 3.4e-16 60.0 2.1 2.2e-14 54.1 2.1 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CS PF04969.16 OWF52399.1 - 0.012 16.6 6.8 0.035 15.1 6.8 1.9 1 1 0 1 1 1 0 CS domain Ntox17 PF15524.6 OWF52399.1 - 0.12 12.6 0.1 0.29 11.5 0.0 1.6 1 1 0 1 1 1 0 Novel toxin 17 ETX_MTX2 PF03318.13 OWF52400.1 - 1.3e-06 28.4 6.1 1.6e-06 28.0 6.1 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Kinesin PF00225.23 OWF52401.1 - 6.7e-117 390.1 0.4 6.7e-117 390.1 0.4 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF52401.1 - 5.4e-28 97.8 0.1 5.4e-28 97.8 0.1 2.1 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 OWF52401.1 - 0.0094 16.4 0.7 0.04 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OWF52401.1 - 0.072 13.4 1.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ribosomal_L27e PF01777.18 OWF52401.1 - 0.18 12.2 5.0 0.27 11.6 1.5 3.1 2 1 0 2 2 2 0 Ribosomal L27e protein family Kinesin_assoc PF16183.5 OWF52401.1 - 2.4 8.3 20.1 39 4.3 17.5 2.8 2 1 0 2 2 2 0 Kinesin-associated DUF4407 PF14362.6 OWF52401.1 - 9.8 5.4 30.7 1.7 7.9 11.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_C14 PF00656.22 OWF52402.1 - 5e-33 115.1 0.0 6.1e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Mab-21 PF03281.14 OWF52403.1 - 1.3e-13 50.9 3.6 3e-13 49.7 3.6 1.5 1 0 0 1 1 1 1 Mab-21 protein Pkinase PF00069.25 OWF52404.1 - 1.5e-46 159.0 0.0 2.2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF52404.1 - 8.4e-45 153.1 0.0 1.2e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S76 PF13611.6 OWF52404.1 - 2.5e-06 27.8 0.0 25 5.2 0.0 7.2 2 2 6 9 9 9 2 Serine peptidase of plant viral polyprotein, P1 Kinase-like PF14531.6 OWF52404.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NTR2 PF15458.6 OWF52404.1 - 0.0031 17.1 0.4 0.44 10.0 0.0 3.3 3 1 1 4 4 4 1 Nineteen complex-related protein 2 VASt PF16016.5 OWF52405.1 - 6e-34 117.7 0.3 6e-34 117.7 0.3 2.1 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OWF52405.1 - 2e-24 85.6 0.1 4.1e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 GRAM domain Podoplanin PF05808.11 OWF52405.1 - 0.15 12.1 0.0 0.15 12.1 0.0 3.4 4 0 0 4 4 4 0 Podoplanin IFT46_B_C PF12317.8 OWF52406.1 - 1e-98 329.3 0.8 1.3e-98 328.9 0.8 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal CENP-B_dimeris PF09026.10 OWF52406.1 - 0.0037 17.6 23.6 0.011 16.1 11.8 2.5 2 0 0 2 2 2 2 Centromere protein B dimerisation domain RXT2_N PF08595.11 OWF52406.1 - 0.088 12.8 10.9 0.11 12.5 4.4 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 OWF52406.1 - 0.1 12.4 10.3 1.3 8.8 0.4 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Treacle PF03546.14 OWF52406.1 - 0.26 10.1 5.3 0.35 9.7 5.3 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle FAM176 PF14851.6 OWF52406.1 - 0.36 10.5 12.1 3.8 7.2 6.3 2.4 2 0 0 2 2 2 0 FAM176 family Cnd2 PF05786.14 OWF52406.1 - 0.44 9.2 9.2 0.56 8.8 9.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 PBP1_TM PF14812.6 OWF52406.1 - 0.96 9.9 17.4 2.7 8.4 10.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYDLN_acid PF09538.10 OWF52406.1 - 1 10.0 16.2 1 10.1 9.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Collagen PF01391.18 OWF52406.1 - 1.6 8.6 15.7 3.4 7.5 15.7 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_60s PF00428.19 OWF52406.1 - 1.9 9.2 10.7 2.8 8.6 3.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 OWF52406.1 - 2.8 8.1 23.9 2.2 8.5 10.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Med15 PF09606.10 OWF52406.1 - 2.8 6.5 23.0 3.8 6.1 23.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NOA36 PF06524.12 OWF52406.1 - 2.9 7.1 21.9 1.2 8.4 12.7 2.1 2 0 0 2 2 2 0 NOA36 protein GEMIN8 PF15348.6 OWF52406.1 - 2.9 8.1 7.9 13 6.0 0.6 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Tim54 PF11711.8 OWF52406.1 - 3 6.5 9.0 0.17 10.6 2.7 1.8 1 1 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 OWF52406.1 - 3.1 7.1 15.8 5.6 6.2 15.8 1.4 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 OWF52406.1 - 5.2 6.7 24.5 0.095 12.4 11.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-B_box PF00643.24 OWF52407.1 - 1.2e-06 28.6 8.0 1.2e-06 28.6 8.0 2.4 2 0 0 2 2 2 1 B-box zinc finger zf-UBR PF02207.20 OWF52407.1 - 0.002 18.3 6.0 0.002 18.3 6.0 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) OTU PF02338.19 OWF52407.1 - 0.0021 18.5 0.4 0.39 11.2 0.0 2.8 2 0 0 2 2 2 1 OTU-like cysteine protease NHL PF01436.21 OWF52407.1 - 0.026 14.6 1.4 2.4 8.3 0.0 3.3 2 1 1 3 3 3 0 NHL repeat ANAPC4_WD40 PF12894.7 OWF52407.1 - 0.074 13.4 2.4 8.9 6.7 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ZZ PF00569.17 OWF52407.1 - 1.2 9.0 6.1 6.7 6.6 6.1 2.3 1 0 0 1 1 1 0 Zinc finger, ZZ type WD40 PF00400.32 OWF52407.1 - 1.4 9.9 5.6 0.27 12.2 0.5 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Ldl_recept_a PF00057.18 OWF52408.1 - 1.2e-50 169.4 105.1 6.5e-13 48.7 11.8 9.2 8 0 0 8 8 8 5 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 OWF52408.1 - 5.6e-11 43.1 0.0 2.4e-10 41.1 0.0 2.2 1 0 0 1 1 1 1 Lectin C-type domain 7tm_1 PF00001.21 OWF52409.1 - 2.6e-70 236.8 6.7 2.9e-70 236.6 6.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF52409.1 - 2.2e-06 27.3 10.4 0.0011 18.4 6.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF52409.1 - 7.4e-05 22.6 0.4 0.00029 20.7 0.6 1.9 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF52409.1 - 0.00019 21.1 10.0 0.00019 21.1 10.0 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HlyD_2 PF12700.7 OWF52409.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF4918 PF16265.5 OWF52410.1 - 3.3e-07 30.1 0.0 7.3e-06 25.7 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4918) UDG PF03167.19 OWF52410.1 - 4.9e-07 29.9 0.0 1.7e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Defensin_beta PF00711.19 OWF52412.1 - 0.28 11.2 0.2 0.28 11.2 0.2 4.2 6 1 0 6 6 6 0 Beta defensin SYF2 PF08231.12 OWF52412.1 - 2.8 8.3 7.6 12 6.2 2.4 2.9 1 1 1 2 2 2 0 SYF2 splicing factor DUF4634 PF15465.6 OWF52413.1 - 0.047 14.0 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) Tis11B_N PF04553.12 OWF52414.1 - 0.1 13.2 12.1 1.3 9.6 1.1 3.6 1 1 2 3 3 3 0 Tis11B like protein, N terminus DUF5029 PF16432.5 OWF52414.1 - 1 8.9 4.0 3.5 7.1 0.2 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5029) DUF4609 PF15382.6 OWF52414.1 - 1.2 9.1 11.9 5.1 7.1 0.5 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF4609) Adipokin_hormo PF06377.11 OWF52415.1 - 0.00055 20.2 3.3 0.73 10.2 0.1 2.6 3 0 0 3 3 3 2 Adipokinetic hormone FAD_binding_7 PF03441.14 OWF52415.1 - 0.078 12.4 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase DUF2841 PF11001.8 OWF52416.1 - 0.037 14.1 0.1 0.094 12.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2841) TFIIA PF03153.13 OWF52416.1 - 4.4 7.2 15.4 5.9 6.8 15.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APH PF01636.23 OWF52417.1 - 6.9e-16 58.9 0.0 1e-15 58.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OWF52417.1 - 0.047 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Roc PF08477.13 OWF52418.1 - 3.8e-11 43.3 0.0 6e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF52418.1 - 6.1e-11 42.5 0.0 1.6e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 OWF52418.1 - 9.1e-10 39.0 0.0 3e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF52418.1 - 6.4e-08 33.0 0.0 2.5e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF52418.1 - 1.2e-05 25.5 0.1 0.0003 21.0 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ras PF00071.22 OWF52418.1 - 1.6e-05 24.6 0.3 0.016 14.8 0.1 2.3 2 0 0 2 2 2 2 Ras family Ank_3 PF13606.6 OWF52418.1 - 1.9e-05 24.7 0.0 0.0067 16.9 0.0 3.9 4 0 0 4 4 3 1 Ankyrin repeat Death PF00531.22 OWF52418.1 - 0.00011 22.3 0.4 0.00046 20.3 0.0 2.3 2 0 0 2 2 2 1 Death domain Ank PF00023.30 OWF52418.1 - 0.0002 21.6 0.1 0.16 12.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Dynamin_N PF00350.23 OWF52418.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 OWF52418.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OWF52418.1 - 0.089 13.1 0.2 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF52418.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 OWF52418.1 - 0.2 12.2 0.1 0.43 11.1 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Tetraspanin PF00335.20 OWF52420.1 - 1.4e-28 100.1 16.7 1.7e-28 99.9 16.7 1.1 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 OWF52420.1 - 0.0051 16.5 7.7 0.0051 16.5 7.7 2.7 2 1 1 3 3 3 1 SUR7/PalI family Coa1 PF08695.10 OWF52420.1 - 0.022 14.5 0.3 0.061 13.1 0.3 1.8 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Transposase_1 PF01359.18 OWF52420.1 - 0.16 11.8 0.5 0.28 11.0 0.5 1.4 1 0 0 1 1 1 0 Transposase (partial DDE domain) Fzo_mitofusin PF04799.13 OWF52420.1 - 0.3 10.6 3.8 0.9 9.1 3.8 1.7 1 1 0 1 1 1 0 fzo-like conserved region DUF3482 PF11981.8 OWF52420.1 - 1.4 8.3 2.8 2.2 7.6 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF5337 PF17272.2 OWF52420.1 - 4.2 7.3 7.0 21 5.0 7.0 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5337) Tetraspanin PF00335.20 OWF52421.1 - 2e-31 109.5 14.9 2.4e-31 109.3 14.9 1.0 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 OWF52422.1 - 2.4e-07 30.7 0.6 2.6e-07 30.6 0.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF5589 PF17672.1 OWF52422.1 - 0.029 14.3 0.2 0.039 13.9 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5589) PDR_assoc PF08370.11 OWF52422.1 - 0.15 11.8 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Tetraspanin PF00335.20 OWF52423.1 - 4.1e-29 101.9 11.3 4.7e-29 101.7 11.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Orf78 PF06024.12 OWF52423.1 - 0.24 11.7 2.7 0.46 10.8 0.6 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Tetraspanin PF00335.20 OWF52424.1 - 5.3e-33 114.7 25.4 3.7e-32 111.9 12.1 2.9 1 1 1 2 2 2 2 Tetraspanin family Leuk-A4-hydro_C PF09127.11 OWF52424.1 - 0.09 12.9 0.6 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal Vps26 PF03643.15 OWF52426.1 - 6.3e-61 205.8 0.8 8.2e-61 205.4 0.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OWF52426.1 - 3.8e-08 33.5 0.0 8.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TRAM_LAG1_CLN8 PF03798.16 OWF52429.1 - 8.4e-14 51.8 16.2 1.9e-13 50.6 15.4 2.0 1 1 1 2 2 2 1 TLC domain Ribosomal_S19e PF01090.19 OWF52430.1 - 8.1e-56 187.5 0.1 9.6e-56 187.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 OWF52430.1 - 0.00067 19.5 0.0 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain SPATIAL PF15256.6 OWF52432.1 - 0.00011 22.7 0.4 0.00013 22.4 0.4 1.3 1 0 0 1 1 1 1 SPATIAL APOBEC_N PF08210.11 OWF52433.1 - 1.4e-09 38.1 0.2 2e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 OWF52433.1 - 3.3e-08 33.8 0.0 4.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 OWF52433.1 - 1e-07 32.0 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 OWF52433.1 - 3.6e-06 27.1 0.0 5.7e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 APOBEC3 APOBEC2 PF18772.1 OWF52433.1 - 4e-06 27.0 0.0 6.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 APOBEC2 APOBEC4 PF18775.1 OWF52433.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 APOBEC4 APOBEC4_like PF18774.1 OWF52433.1 - 0.00027 20.9 0.0 0.00059 19.8 0.0 1.6 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase Trypan_PARP PF05887.11 OWF52433.1 - 0.00051 20.0 15.0 0.00051 20.0 15.0 1.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) APOBEC1 PF18769.1 OWF52433.1 - 0.00056 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 APOBEC1 NAD2 PF18782.1 OWF52433.1 - 0.0023 18.1 0.0 0.0038 17.4 0.0 1.5 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 NESP55 PF06390.12 OWF52433.1 - 0.75 9.3 10.6 1.4 8.5 10.6 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Lectin_C PF00059.21 OWF52434.1 - 2.7e-20 73.1 1.7 6.1e-11 43.0 0.4 2.1 2 0 0 2 2 2 2 Lectin C-type domain AMP-binding PF00501.28 OWF52435.1 - 1.1e-108 363.6 0.0 1.3e-108 363.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF52435.1 - 1e-17 64.8 0.3 2.3e-17 63.7 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_33 PF13592.6 OWF52435.1 - 0.049 13.3 0.6 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix AMP-binding_C_2 PF14535.6 OWF52435.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain bZIP_1 PF00170.21 OWF52436.1 - 4e-08 33.2 12.5 6.2e-08 32.6 12.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF52436.1 - 6.1e-07 29.4 15.7 9.7e-07 28.8 15.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OWF52436.1 - 0.00057 20.3 13.9 0.00092 19.7 13.9 1.4 1 1 0 1 1 1 1 bZIP Maf transcription factor FapA PF03961.13 OWF52436.1 - 0.18 10.3 1.6 0.22 10.1 1.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 OWF52436.1 - 0.35 11.4 8.0 0.52 10.8 8.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1515 PF07439.11 OWF52436.1 - 1.4 9.0 4.5 3.1 7.9 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) OrfB_IS605 PF01385.19 OWF52436.1 - 1.9 8.7 7.0 0.25 11.6 0.9 2.0 1 1 1 2 2 2 0 Probable transposase DUF2407 PF10302.9 OWF52437.1 - 0.035 14.7 0.5 0.045 14.3 0.5 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PPR_long PF17177.4 OWF52438.1 - 0.012 14.9 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP CARD_2 PF16739.5 OWF52438.1 - 0.038 14.0 0.1 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Caspase recruitment domain CARD PF00619.21 OWF52438.1 - 0.054 13.5 0.3 0.21 11.6 0.1 2.1 2 1 0 2 2 2 0 Caspase recruitment domain Med9 PF07544.13 OWF52438.1 - 0.1 12.7 0.1 0.34 11.0 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CARD PF00619.21 OWF52439.1 - 0.077 13.0 0.1 0.26 11.4 0.1 2.0 1 0 0 1 1 1 0 Caspase recruitment domain PPR_long PF17177.4 OWF52439.1 - 0.079 12.3 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP SapA PF02199.15 OWF52441.1 - 0.082 13.2 0.2 0.082 13.2 0.2 6.7 4 3 2 6 6 6 0 Saposin A-type domain UNC-50 PF05216.13 OWF52441.1 - 9.1 5.8 13.4 13 5.3 0.1 3.6 1 1 1 3 3 3 0 UNC-50 family Metallothi_Euk2 PF12809.7 OWF52442.1 - 0.11 12.7 13.4 10 6.5 0.4 4.8 1 1 3 5 5 5 0 Eukaryotic metallothionein UCH PF00443.29 OWF52443.1 - 1.5e-62 211.4 3.6 1.7e-62 211.3 3.6 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF52443.1 - 1.7e-34 119.9 6.2 2.1e-34 119.6 6.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OWF52443.1 - 1.1e-07 31.7 10.6 1.8e-07 30.9 7.1 2.3 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_L21e PF01157.18 OWF52444.1 - 1.3e-48 162.9 7.5 1.3e-48 162.9 7.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e TNFR_c6 PF00020.18 OWF52445.1 - 1.7e-20 73.1 81.9 3.8e-08 33.6 7.4 7.6 8 0 0 8 8 8 5 TNFR/NGFR cysteine-rich region 7tm_1 PF00001.21 OWF52446.1 - 2.2e-17 63.3 6.5 2.9e-17 62.9 6.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.9 OWF52446.1 - 0.0032 16.5 6.3 0.0071 15.4 6.3 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt Git3 PF11710.8 OWF52446.1 - 0.009 15.8 8.3 0.009 15.8 8.3 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 DASH_Dad4 PF08650.10 OWF52446.1 - 0.07 13.1 1.9 0.16 12.0 0.6 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad4 S_4TM PF18159.1 OWF52446.1 - 0.4 9.9 5.4 2.7 7.2 0.1 3.2 4 0 0 4 4 4 0 SMODS-associating 4TM effector domain Srg PF02118.21 OWF52446.1 - 2.3 7.8 20.5 3.4 7.2 15.3 2.8 2 1 0 2 2 2 0 Srg family chemoreceptor SpoIIM PF01944.17 OWF52446.1 - 2.6 8.1 9.0 1.6 8.8 4.1 2.5 3 0 0 3 3 3 0 Stage II sporulation protein M 7tm_1 PF00001.21 OWF52447.1 - 3.3e-20 72.5 0.1 5.6e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.9 OWF52447.1 - 0.11 11.4 20.0 0.06 12.3 7.4 2.7 2 2 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srt HSP70 PF00012.20 OWF52448.1 - 2.2e-10 39.4 0.0 8.2e-09 34.2 0.0 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF52448.1 - 0.22 10.3 1.9 1.9 7.3 0.3 2.4 2 1 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 OWF52449.1 - 7.3e-09 34.4 0.0 1.9e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF52449.1 - 0.024 13.5 0.6 0.72 8.6 0.2 2.5 2 1 0 2 2 2 0 MreB/Mbl protein DDR PF08841.10 OWF52449.1 - 0.083 11.9 0.1 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 OWF52450.1 - 4.9e-10 38.2 0.0 0.00016 20.0 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OWF52450.1 - 0.00036 19.5 1.4 0.43 9.4 0.3 2.5 2 1 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 OWF52450.1 - 0.0027 16.7 0.1 0.021 13.8 0.1 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 OWF52451.1 - 1.1e-11 43.7 0.1 1.7e-10 39.7 0.1 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF52451.1 - 0.015 14.1 0.1 2.2 7.0 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein DDR PF08841.10 OWF52451.1 - 0.067 12.2 0.1 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 OWF52452.1 - 8.7e-11 40.7 0.1 6.4e-10 37.8 0.1 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF52452.1 - 0.0057 15.5 0.3 0.051 12.4 0.1 2.4 2 1 0 2 2 2 1 MreB/Mbl protein 7tm_1 PF00001.21 OWF52453.1 - 2.6e-19 69.6 8.7 3e-19 69.4 8.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2839 PF10999.8 OWF52453.1 - 0.9 9.9 5.1 16 5.9 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Cerato-platanin PF07249.12 OWF52454.1 - 2.3e-05 24.5 19.7 3.9 7.6 0.1 8.5 1 1 10 12 12 12 7 Cerato-platanin FAD_oxidored PF12831.7 OWF52454.1 - 1.1 8.6 2.0 1e+02 2.1 0.1 3.9 1 1 1 4 4 4 0 FAD dependent oxidoreductase Ank_2 PF12796.7 OWF52455.1 - 1.3e-29 102.6 2.9 1.9e-10 41.2 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 OWF52455.1 - 3.9e-21 75.5 14.2 3.9e-21 75.5 14.2 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 OWF52455.1 - 7e-19 67.9 9.9 2e-07 31.4 0.1 7.0 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF52455.1 - 1.8e-18 64.7 4.6 0.00021 21.4 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OWF52455.1 - 2.4e-18 65.7 1.2 0.00017 21.9 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF52455.1 - 2.8e-18 65.7 1.2 3.5e-06 27.2 0.3 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Adeno_100 PF02438.16 OWF52455.1 - 0.045 11.9 0.4 1.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Late 100kD protein EzrA PF06160.12 OWF52456.1 - 0.0045 15.2 0.3 0.0066 14.7 0.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SPK PF04435.18 OWF52456.1 - 0.018 15.5 0.8 0.05 14.0 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF545) CIMR PF00878.18 OWF52457.1 - 0 1009.9 93.6 4e-34 117.7 0.5 16.3 16 0 0 16 16 16 16 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 OWF52457.1 - 1.8e-78 264.1 82.0 2.8e-09 37.2 5.2 16.5 2 1 12 14 14 14 13 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF52457.1 - 3.2e-55 187.0 30.5 5.5e-09 35.5 0.0 13.3 6 3 7 14 14 14 11 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 OWF52457.1 - 5.7e-07 29.3 42.8 0.34 10.6 0.1 10.9 11 1 1 12 12 12 6 Glucosidase II beta subunit-like protein DUF402 PF04167.13 OWF52457.1 - 0.14 12.3 0.7 35 4.7 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF402) GTP_EFTU PF00009.27 OWF52458.1 - 1.4e-57 194.4 0.0 2.2e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OWF52458.1 - 3.7e-27 94.5 0.0 8e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OWF52458.1 - 4.4e-22 77.9 0.0 8.9e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OWF52458.1 - 2.4e-12 47.0 0.9 6.9e-11 42.4 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OWF52458.1 - 6.6e-11 42.1 0.0 1.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Malic_M PF03949.15 OWF52459.1 - 6.3e-97 323.9 0.2 8.2e-97 323.5 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OWF52459.1 - 4.4e-81 271.0 0.0 7e-81 270.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2680 PF10925.8 OWF52460.1 - 2.6 8.1 14.8 1.1 9.3 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2680) PDZ PF00595.24 OWF52461.1 - 1.6e-14 54.0 0.7 3.1e-14 53.1 0.7 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF52461.1 - 6.4e-05 22.7 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Shugoshin_N PF07558.11 OWF52461.1 - 0.0057 16.5 1.5 0.015 15.2 1.5 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region MazG PF03819.17 OWF52461.1 - 0.014 15.6 1.6 0.027 14.6 0.3 2.2 1 1 1 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain PDZ_2 PF13180.6 OWF52461.1 - 0.026 14.8 0.1 0.069 13.5 0.0 1.8 2 0 0 2 2 2 0 PDZ domain DUF4763 PF15960.5 OWF52461.1 - 0.25 10.6 8.5 0.4 9.9 7.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) bZIP_2 PF07716.15 OWF52461.1 - 0.27 11.4 5.9 0.44 10.7 3.6 2.7 1 1 1 2 2 2 0 Basic region leucine zipper HLH PF00010.26 OWF52462.1 - 5.2e-14 51.9 0.8 2e-13 50.1 0.3 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain CDH PF02611.15 OWF52462.1 - 0.029 14.0 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Ribosom_S30AE_C PF16321.5 OWF52462.1 - 0.14 11.9 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma 54 modulation/S30EA ribosomal protein C terminus zn-ribbon_14 PF16503.5 OWF52463.1 - 4.6e-18 64.4 3.0 4.6e-18 64.4 3.0 2.8 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 OWF52463.1 - 1.3e-16 60.9 0.0 1.8e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 PP-loop family TF_Zn_Ribbon PF08271.12 OWF52463.1 - 0.016 14.7 0.2 0.016 14.7 0.2 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding tRNA_Me_trans PF03054.16 OWF52463.1 - 0.061 12.1 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TERB2 PF15101.6 OWF52464.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.2 2 1 1 3 3 3 0 Telomere-associated protein TERB2 B2-adapt-app_C PF09066.10 OWF52464.1 - 0.14 12.2 3.1 0.69 10.0 0.1 2.7 2 1 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain K1377 PF15352.6 OWF52465.1 - 2.7e-14 52.5 3.2 2.7e-14 52.5 3.2 6.3 4 3 2 7 7 7 3 Susceptibility to monomelic amyotrophy Atg14 PF10186.9 OWF52466.1 - 0.0014 17.7 14.7 0.0014 17.7 14.7 6.4 4 1 3 7 7 7 3 Vacuolar sorting 38 and autophagy-related subunit 14 PTR PF12789.7 OWF52466.1 - 2.8 8.1 5.9 16 5.6 0.0 3.8 4 0 0 4 4 4 0 Phage tail repeat like DUF1843 PF08898.10 OWF52466.1 - 7.1 7.2 7.7 0.46 11.0 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DnaJ PF00226.31 OWF52467.1 - 1.2e-14 54.2 0.2 2.7e-14 53.0 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Syncollin PF15138.6 OWF52467.1 - 0.066 13.4 0.2 0.21 11.8 0.2 1.8 2 0 0 2 2 2 0 Syncollin Carn_acyltransf PF00755.20 OWF52468.1 - 5.2e-196 652.8 0.0 6e-196 652.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 OWF52468.1 - 3.8e-25 87.6 0.6 7.7e-25 86.6 0.6 1.6 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus Phosphorylase PF00343.20 OWF52469.1 - 0 1124.2 0.0 0 1124.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3265 PF11665.8 OWF52469.1 - 0.067 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) DUF4732 PF15876.5 OWF52470.1 - 0.00019 21.6 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4732) EGF_MSP1_1 PF12946.7 OWF52470.1 - 0.091 12.8 0.4 6.6 6.9 0.0 2.8 2 0 0 2 2 2 0 MSP1 EGF domain 1 TPR_12 PF13424.6 OWF52471.1 - 1.1e-25 89.7 2.0 2.1e-06 27.9 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat Rapsyn_N PF10579.9 OWF52471.1 - 2.4e-15 56.4 0.6 2.3e-14 53.3 0.1 2.6 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_1 PF00515.28 OWF52471.1 - 1.4e-14 53.2 9.2 0.034 14.0 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OWF52471.1 - 1.4e-13 49.8 8.3 0.33 11.2 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF52471.1 - 1.5e-09 37.7 0.0 3.4e-08 33.3 0.0 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 OWF52471.1 - 7.2e-08 31.9 11.0 0.04 13.9 0.1 7.0 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF52471.1 - 2e-07 30.7 0.2 4.2 7.4 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF52471.1 - 1.2e-06 28.3 3.9 1.5 9.3 0.0 6.8 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF52471.1 - 1.5e-06 28.6 2.8 1 9.9 0.2 4.4 3 2 1 4 4 4 3 Tetratricopeptide repeat RPN7 PF10602.9 OWF52471.1 - 2.2e-06 27.5 0.3 0.039 13.7 0.0 3.7 2 1 1 3 3 3 1 26S proteasome subunit RPN7 SNAP PF14938.6 OWF52471.1 - 1.2e-05 24.9 4.5 5.4e-05 22.8 0.7 2.9 2 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 OWF52471.1 - 1.7e-05 25.3 1.3 8.2 7.5 0.0 5.2 4 1 2 6 6 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF52471.1 - 0.0001 22.9 0.2 4.3 8.1 0.0 5.6 7 0 0 7 7 6 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 OWF52471.1 - 0.00014 22.1 2.9 0.00014 22.1 2.9 2.4 3 0 0 3 3 1 1 Ring finger domain ANAPC3 PF12895.7 OWF52471.1 - 0.00018 21.6 10.0 0.41 10.9 0.9 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_5 PF14634.6 OWF52471.1 - 0.00028 20.8 1.5 0.00028 20.8 1.5 2.1 2 0 0 2 2 1 1 zinc-RING finger domain Sel1 PF08238.12 OWF52471.1 - 0.0019 18.8 0.0 4.4 8.1 0.0 2.9 2 0 0 2 2 2 1 Sel1 repeat zf-C3HC4_3 PF13920.6 OWF52471.1 - 0.0023 17.7 1.1 0.0023 17.7 1.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF52471.1 - 0.0062 16.3 0.6 0.02 14.6 0.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OWF52471.1 - 0.0076 16.1 1.2 0.0076 16.1 1.2 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF52471.1 - 0.0083 16.1 3.0 0.0083 16.1 3.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger TPR_11 PF13414.6 OWF52471.1 - 0.011 15.4 8.6 0.43 10.3 0.0 5.7 7 0 0 7 7 6 0 TPR repeat TPR_15 PF13429.6 OWF52471.1 - 0.045 13.0 0.5 6.6 5.8 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 OWF52471.1 - 0.11 11.9 0.1 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 OWF52471.1 - 0.12 12.4 2.8 72 3.6 0.1 4.2 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 OWF52471.1 - 0.13 12.3 3.8 3.7 7.7 0.0 3.6 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 OWF52471.1 - 0.17 12.0 5.9 0.21 11.7 0.3 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 OWF52471.1 - 0.2 12.4 8.5 3 8.7 0.9 4.9 5 1 1 6 6 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 OWF52473.1 - 1.8e-30 104.5 1.2 7.4e-15 54.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF52473.1 - 7.3e-11 41.7 0.0 1.1e-05 25.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF52473.1 - 2.7e-07 30.4 0.1 0.0057 16.5 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 OWF52473.1 - 0.00032 20.5 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) LURAP PF14854.6 OWF52474.1 - 3.5e-06 26.9 0.4 3.5e-06 26.9 0.4 2.3 1 1 0 2 2 2 1 Leucine rich adaptor protein CENP-F_leu_zip PF10473.9 OWF52474.1 - 0.085 12.9 0.7 0.13 12.3 0.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3490 PF11995.8 OWF52474.1 - 0.085 12.7 0.7 0.1 12.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) LURAP PF14854.6 OWF52475.1 - 3.7e-07 30.1 2.9 6e-07 29.4 2.9 1.6 1 1 0 1 1 1 1 Leucine rich adaptor protein CENP-H PF05837.12 OWF52475.1 - 0.015 15.7 1.4 0.017 15.5 1.4 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4530 PF15039.6 OWF52475.1 - 0.015 15.4 0.3 0.025 14.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) Vac_Fusion PF02346.16 OWF52475.1 - 0.044 13.4 1.2 0.072 12.7 0.1 1.9 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Macoilin PF09726.9 OWF52475.1 - 0.12 10.9 2.1 0.14 10.7 2.1 1.0 1 0 0 1 1 1 0 Macoilin family Herpes_glycop PF01528.16 OWF52475.1 - 0.42 9.4 0.6 0.48 9.2 0.6 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M LURAP PF14854.6 OWF52476.1 - 3.7e-06 26.9 0.3 5.6e-06 26.3 0.0 1.4 2 0 0 2 2 2 1 Leucine rich adaptor protein DUF4530 PF15039.6 OWF52476.1 - 0.21 11.8 0.6 0.32 11.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) LURAP PF14854.6 OWF52477.1 - 5.6e-06 26.3 0.3 5.6e-06 26.3 0.3 2.1 1 1 1 2 2 2 1 Leucine rich adaptor protein ATG16 PF08614.11 OWF52477.1 - 0.03 14.6 2.2 0.03 14.6 2.2 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 OWF52477.1 - 0.11 13.0 1.9 0.26 11.7 0.4 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 OWF52477.1 - 0.46 10.9 3.9 1 9.8 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 OWF52477.1 - 0.72 9.9 6.2 1 9.4 1.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LURAP PF14854.6 OWF52478.1 - 1.3e-07 31.6 4.7 4.4e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 Leucine rich adaptor protein CENP-F_leu_zip PF10473.9 OWF52478.1 - 0.075 13.1 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LURAP PF14854.6 OWF52479.1 - 3.2e-06 27.1 0.4 3.2e-06 27.1 0.4 1.8 2 1 0 2 2 2 1 Leucine rich adaptor protein Peptidase_M54 PF07998.11 OWF52479.1 - 0.016 15.2 1.3 0.023 14.7 1.3 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF4530 PF15039.6 OWF52479.1 - 0.019 15.1 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF4611 PF15387.6 OWF52479.1 - 0.035 14.3 0.2 0.079 13.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF327 PF03885.13 OWF52479.1 - 0.038 14.0 1.0 0.073 13.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF327) HD_2 PF12917.7 OWF52479.1 - 0.085 12.6 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Death PF00531.22 OWF52480.1 - 4.8e-20 71.5 0.4 2e-09 37.5 0.0 2.9 2 0 0 2 2 2 2 Death domain ZU5 PF00791.20 OWF52480.1 - 7.1e-06 26.3 0.2 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 2 ZU5 domain DUF4732 PF15876.5 OWF52481.1 - 0.095 12.8 0.3 0.37 10.9 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4732) His_Phos_1 PF00300.22 OWF52482.1 - 1.7e-41 142.0 0.2 2.9e-36 125.0 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SDA1 PF05285.12 OWF52482.1 - 0.11 11.9 10.5 0.17 11.3 10.5 1.2 1 0 0 1 1 1 0 SDA1 SieB PF14163.6 OWF52484.1 - 0.0092 15.5 1.1 1.3 8.6 0.3 2.1 2 0 0 2 2 2 2 Super-infection exclusion protein B Lig_chan PF00060.26 OWF52486.1 - 7.9e-25 87.4 0.4 1e-24 87.1 0.4 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF52486.1 - 9.4e-12 45.1 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF52486.1 - 1.4e-10 41.0 0.0 4.6e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 E1_DerP2_DerF2 PF02221.15 OWF52487.1 - 5.6e-11 43.0 0.0 8.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ML domain Bombesin PF02044.17 OWF52487.1 - 1.9 8.7 3.8 12 6.3 0.3 2.6 2 0 0 2 2 2 0 Bombesin-like peptide E1_DerP2_DerF2 PF02221.15 OWF52488.1 - 1.7e-13 51.2 0.0 2.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 OWF52489.1 - 1.7e-14 54.4 0.3 2e-14 54.2 0.3 1.1 1 0 0 1 1 1 1 ML domain Mo-nitro_C PF06967.11 OWF52489.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Mo-dependent nitrogenase C-terminus Pkinase PF00069.25 OWF52490.1 - 6e-78 261.8 0.2 9.2e-78 261.2 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF52490.1 - 9.1e-44 149.7 0.1 1.3e-43 149.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF52490.1 - 6.6e-08 32.2 0.1 9.9e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OWF52490.1 - 1.7e-05 24.5 0.5 3e-05 23.7 0.5 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OWF52490.1 - 1.9e-05 24.1 0.0 0.0004 19.8 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF52490.1 - 0.00024 20.0 0.5 0.00048 19.0 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OWF52490.1 - 0.00064 19.3 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 OWF52490.1 - 0.034 13.1 0.0 0.063 12.2 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OWF52490.1 - 0.17 11.8 0.0 6.4 6.6 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OWF52490.1 - 0.17 11.4 0.4 0.72 9.4 0.1 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Mito_carr PF00153.27 OWF52493.1 - 4.5e-17 61.8 0.1 2e-07 30.8 0.0 2.5 3 0 0 3 3 3 2 Mitochondrial carrier protein TM_helix PF05552.12 OWF52493.1 - 0.034 14.1 0.4 2.5 8.1 0.1 2.7 2 0 0 2 2 2 0 Conserved TM helix TPD PF14811.6 OWF52494.1 - 9.7e-58 193.9 0.2 1.6e-57 193.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif SASA PF03629.18 OWF52495.1 - 7.7e-15 55.1 0.0 1.5e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase SASA PF03629.18 OWF52497.1 - 4.2e-12 46.2 0.0 4.4e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DED PF01335.21 OWF52498.1 - 1.4e-08 34.9 0.0 0.0001 22.6 0.1 2.6 2 0 0 2 2 2 2 Death effector domain Peptidase_C14 PF00656.22 OWF52498.1 - 9.9e-06 25.7 0.0 1.8e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Caspase domain SASA PF03629.18 OWF52499.1 - 2.9e-10 40.2 0.0 0.00017 21.3 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase DUF656 PF04920.12 OWF52499.1 - 0.0048 16.8 0.4 0.011 15.6 0.4 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF656) GFO_IDH_MocA PF01408.22 OWF52500.1 - 1.1e-16 61.7 0.5 5.1e-16 59.6 0.3 2.1 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OWF52500.1 - 0.00021 21.9 0.0 0.00033 21.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Biliv-reduc_cat PF09166.10 OWF52500.1 - 0.016 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Biliverdin reductase, catalytic NAD_binding_7 PF13241.6 OWF52500.1 - 0.055 13.9 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-C3HC4_3 PF13920.6 OWF52501.1 - 8e-12 44.8 13.4 8e-12 44.8 13.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 OWF52501.1 - 1.6e-08 34.3 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-RanBP PF00641.18 OWF52501.1 - 2.7e-05 23.4 7.2 8.3e-05 21.8 7.2 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zinc_ribbon_15 PF17032.5 OWF52501.1 - 0.011 16.4 1.5 0.011 16.4 1.5 2.8 2 0 0 2 2 2 0 zinc-ribbon family DZR PF12773.7 OWF52501.1 - 0.15 12.1 19.2 0.081 13.0 1.5 3.5 2 1 1 3 3 3 0 Double zinc ribbon zf-FPG_IleRS PF06827.14 OWF52501.1 - 0.19 11.6 8.2 0.064 13.1 1.0 2.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_2 PF13240.6 OWF52501.1 - 2 8.3 17.3 0.96 9.3 5.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DIOX_N PF14226.6 OWF52502.1 - 3.9e-23 82.4 0.0 1.3e-22 80.7 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OWF52502.1 - 3.3e-18 66.0 0.0 6.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OWF52503.1 - 1.4e-21 77.5 0.0 1.8e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OWF52503.1 - 6.2e-05 23.4 0.0 0.00018 22.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sulfotransfer_1 PF00685.27 OWF52504.1 - 5.5e-46 157.2 0.5 1.5e-44 152.5 0.5 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF52504.1 - 1.3e-05 25.7 0.0 0.00013 22.4 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family Methyltransf_11 PF08241.12 OWF52505.1 - 2.4e-12 47.3 0.0 3.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF52505.1 - 2.6e-12 47.3 0.0 4.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF52505.1 - 8.3e-09 35.5 0.0 1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF52505.1 - 1.9e-08 34.2 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF52505.1 - 6.6e-08 32.2 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OWF52505.1 - 1.5e-07 32.1 0.0 2.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 OWF52505.1 - 3.2e-05 23.6 0.0 4.1e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 OWF52505.1 - 0.0035 16.9 0.0 0.0044 16.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 OWF52505.1 - 0.005 15.5 0.0 0.005 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 OWF52505.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 OWF52505.1 - 0.051 13.4 0.0 0.057 13.3 0.0 1.3 1 1 0 1 1 1 0 Hypothetical methyltransferase Inhibitor_I78 PF11720.8 OWF52505.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I78 family zf-DNL PF05180.12 OWF52505.1 - 0.095 12.6 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 DNL zinc finger E3_UFM1_ligase PF09743.9 OWF52506.1 - 4.3e-110 367.6 1.9 7e-110 366.9 1.9 1.3 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 LRR_8 PF13855.6 OWF52507.1 - 7.6e-16 57.6 11.6 1.1e-08 34.7 0.4 4.7 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OWF52507.1 - 1.8e-05 25.0 20.6 0.0016 18.8 3.8 4.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) DUF4446 PF14584.6 OWF52507.1 - 0.17 11.9 0.5 0.39 10.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) LRR_1 PF00560.33 OWF52507.1 - 0.26 12.0 9.1 6.9 7.6 0.4 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat zf-H2C2_5 PF13909.6 OWF52508.1 - 9.3e-15 54.1 70.5 0.0013 18.4 0.6 10.9 10 0 0 10 10 10 8 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 OWF52508.1 - 1.2e-14 53.9 79.4 7.3e-06 26.2 0.5 11.4 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF52508.1 - 8.3e-11 41.8 80.1 0.14 13.1 0.1 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF52508.1 - 3.1e-10 39.9 84.0 0.072 13.6 0.7 10.7 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 OWF52508.1 - 0.0038 17.9 4.2 0.0038 17.9 4.2 7.4 4 2 1 6 6 6 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OWF52508.1 - 8.6 6.8 56.0 0.33 11.3 0.4 7.9 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) SHR-BD PF06650.12 OWF52509.1 - 1.2e-76 257.7 0.0 4.5e-75 252.5 0.0 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 OWF52509.1 - 3.5e-62 210.3 4.4 1.7e-61 208.1 0.6 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 OWF52509.1 - 3.3e-49 167.4 20.4 2.2e-41 141.8 0.9 7.5 8 0 0 8 8 8 4 Repeating coiled region of VPS13 Chorein_N PF12624.7 OWF52509.1 - 3.4e-36 123.9 1.6 6.1e-36 123.1 0.4 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OWF52509.1 - 4.3e-21 75.5 9.1 7.6e-19 68.2 1.5 3.6 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal UBA PF00627.31 OWF52509.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Syja_N PF02383.18 OWF52510.1 - 3e-78 263.4 1.2 8.3e-78 261.9 0.1 2.1 2 0 0 2 2 2 1 SacI homology domain DUF4972 PF16342.5 OWF52511.1 - 0.28 10.9 0.1 0.28 10.9 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) APG17 PF04108.12 OWF52512.1 - 0.0041 16.3 7.3 0.071 12.2 0.3 2.5 2 0 0 2 2 2 2 Autophagy protein Apg17 BORCS8 PF10167.9 OWF52512.1 - 0.12 12.3 1.8 0.35 10.8 0.5 2.6 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 Laminin_II PF06009.12 OWF52512.1 - 0.28 11.2 3.5 2.5 8.1 0.1 3.6 4 0 0 4 4 4 0 Laminin Domain II LOH1CR12 PF10158.9 OWF52512.1 - 0.74 9.8 4.0 9.8 6.2 0.4 3.3 3 0 0 3 3 3 0 Tumour suppressor protein TMPIT PF07851.13 OWF52512.1 - 1 8.6 7.5 1.8 7.7 1.6 3.0 2 1 1 3 3 3 0 TMPIT-like protein zf-C4H2 PF10146.9 OWF52512.1 - 1.3 9.2 4.1 0.67 10.2 0.6 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein FixS PF03597.15 OWF52513.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type RCC1 PF00415.18 OWF52514.1 - 3.2e-77 255.0 14.0 9e-13 48.6 0.1 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF52514.1 - 1.3e-36 123.6 21.7 1.2e-07 31.4 0.0 7.5 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Mcl1_mid PF12341.8 OWF52514.1 - 0.025 14.0 0.0 1.1 8.5 0.0 2.5 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region NDC10_II PF16787.5 OWF52515.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 MscS_TM PF12794.7 OWF52515.1 - 0.13 11.1 0.4 0.2 10.5 0.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1647 PF07801.11 OWF52516.1 - 1.4e-12 47.6 0.1 2.9e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) OapA_N PF08525.11 OWF52516.1 - 0.24 11.4 0.9 0.58 10.2 0.9 1.7 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Popeye PF04831.13 OWF52517.1 - 2.2e-44 151.0 2.6 2.9e-44 150.7 2.6 1.1 1 0 0 1 1 1 1 Popeye protein conserved region Phage_TTP_12 PF16461.5 OWF52517.1 - 0.029 14.1 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP cNMP_binding PF00027.29 OWF52517.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF2838 PF10998.8 OWF52517.1 - 0.41 10.9 6.9 4.2 7.6 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Popeye PF04831.13 OWF52518.1 - 5.4e-45 153.0 1.3 8.8e-45 152.3 1.3 1.3 1 0 0 1 1 1 1 Popeye protein conserved region Sulfotransfer_1 PF00685.27 OWF52520.1 - 3.3e-39 135.0 0.3 5.2e-38 131.1 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Cyclophil_like2 PF18050.1 OWF52520.1 - 0.0062 16.5 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin-like family Sulfotransfer_3 PF13469.6 OWF52520.1 - 0.016 15.6 0.0 0.16 12.3 0.0 2.1 1 1 1 2 2 2 0 Sulfotransferase family SIR2 PF02146.17 OWF52522.1 - 4.9e-27 95.0 0.9 8.4e-21 74.7 0.2 2.6 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 OWF52522.1 - 3.9e-05 23.4 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain CutA1 PF03091.15 OWF52522.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein FAD_binding_6 PF00970.24 OWF52523.1 - 0.0015 18.8 3.5 21 5.5 0.0 4.9 3 2 0 4 4 4 2 Oxidoreductase FAD-binding domain Smoa_sbd PF17885.1 OWF52523.1 - 0.022 14.8 26.7 9.5 6.4 0.1 8.3 1 1 7 8 8 8 0 Styrene monooxygenase A putative substrate binding domain Orthopox_B11R PF07033.11 OWF52523.1 - 1.4 8.7 30.6 2.5 8.0 0.1 6.6 2 1 6 8 8 8 0 Orthopoxvirus B11R protein Rhodanese PF00581.20 OWF52524.1 - 2.2e-22 79.6 0.0 3.8e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Crystall_3 PF08964.10 OWF52524.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin Protocadherin PF08374.11 OWF52525.1 - 0.0055 16.7 0.0 0.0055 16.7 0.0 2.7 2 1 1 3 3 3 1 Protocadherin Adeno_E3_CR2 PF02439.15 OWF52525.1 - 0.027 14.2 1.1 0.056 13.2 1.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIC3 PF15361.6 OWF52525.1 - 0.061 13.7 1.1 3 8.2 0.0 3.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 EphA2_TM PF14575.6 OWF52525.1 - 0.095 13.6 0.0 0.36 11.7 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 OWF52525.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FAM163 PF15069.6 OWF52525.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 FAM163 family FAM176 PF14851.6 OWF52525.1 - 1 9.0 0.0 1 9.0 0.0 2.8 4 0 0 4 4 4 0 FAM176 family Plexin_cytopl PF08337.12 OWF52526.1 - 1.3e-138 463.2 10.4 1.6e-138 462.8 10.4 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 OWF52526.1 - 4.5e-29 100.3 26.8 4e-10 39.6 4.5 5.4 5 0 0 5 5 5 5 IPT/TIG domain Lectin_N PF03954.14 OWF52526.1 - 0.0037 17.0 0.8 0.0084 15.8 0.0 1.9 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain PSI PF01437.25 OWF52526.1 - 0.008 16.7 5.5 0.021 15.4 5.5 1.7 1 0 0 1 1 1 1 Plexin repeat Caveolin PF01146.17 OWF52529.1 - 8.3e-39 132.6 0.0 1.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Caveolin Lectin_C PF00059.21 OWF52530.1 - 9.9e-21 74.5 1.2 1.2e-20 74.3 0.6 1.4 1 1 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF52530.1 - 0.013 15.2 0.2 0.019 14.6 0.2 1.3 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like MBOAT PF03062.19 OWF52531.1 - 5.8e-16 58.8 14.9 5.8e-16 58.8 14.9 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family FUSC_2 PF13515.6 OWF52531.1 - 0.00014 22.0 12.2 0.0022 18.1 0.9 2.8 2 0 0 2 2 2 2 Fusaric acid resistance protein-like TMEM132D_C PF15706.5 OWF52531.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.4 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term VWA_N2 PF16164.5 OWF52532.1 - 0.032 14.4 2.5 0.032 14.4 2.5 2.4 2 1 0 2 2 2 0 VWA N-terminal Sushi PF00084.20 OWF52533.1 - 9.8e-57 189.4 24.7 2.9e-13 50.2 0.5 7.4 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) Trypsin PF00089.26 OWF52533.1 - 5.9e-56 189.8 0.2 1.4e-55 188.5 0.4 1.5 2 0 0 2 2 2 1 Trypsin HRM PF02793.22 OWF52533.1 - 1.1e-05 25.6 25.0 0.15 12.4 0.7 6.2 6 0 0 6 6 6 4 Hormone receptor domain Trypsin_2 PF13365.6 OWF52533.1 - 0.0015 19.5 0.1 0.0034 18.3 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF52533.1 - 0.041 14.3 0.2 0.085 13.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Pentapeptide_4 PF13599.6 OWF52536.1 - 0.043 14.0 25.8 1.5 9.1 3.9 4.9 1 1 5 6 6 6 0 Pentapeptide repeats (9 copies) DUF2012 PF09430.10 OWF52536.1 - 8.4 6.5 39.3 7.4 6.7 1.2 8.2 2 1 3 6 6 6 0 Protein of unknown function (DUF2012) cNMP_binding PF00027.29 OWF52537.1 - 5.8e-16 58.4 0.0 1.7e-12 47.2 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 OWF52537.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Rhodanese PF00581.20 OWF52538.1 - 2.2e-10 41.0 0.0 4.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Abhydrolase_1 PF00561.20 OWF52539.1 - 9.9e-14 51.6 0.1 1.4e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF52539.1 - 6e-09 36.8 0.0 9.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 OWF52539.1 - 0.0002 20.5 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 OWF52539.1 - 0.00055 19.3 0.0 0.00083 18.7 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Carb_anhydrase PF00194.21 OWF52544.1 - 8.4e-90 300.7 0.0 9.6e-90 300.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HSP70 PF00012.20 OWF52545.1 - 6.9e-14 51.0 0.3 4.5e-13 48.3 0.3 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF52545.1 - 0.071 11.9 0.4 0.26 10.1 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein PE_PPE_C PF12484.8 OWF52545.1 - 0.15 13.0 0.0 0.29 12.1 0.0 1.4 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal COG7 PF10191.9 OWF52546.1 - 3e-205 683.9 21.6 4.1e-205 683.4 21.6 1.2 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) COG5 PF10392.9 OWF52546.1 - 3e-05 24.2 5.1 3e-05 24.2 5.1 3.6 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF717 PF05338.12 OWF52546.1 - 0.002 18.2 0.1 0.019 15.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF717) DUF2019 PF09450.10 OWF52546.1 - 0.06 13.3 1.3 0.16 12.0 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) Poxvirus_B22R_N PF13169.6 OWF52546.1 - 0.16 12.4 1.3 0.61 10.6 0.3 2.5 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal Baculo_PEP_C PF04513.12 OWF52546.1 - 0.25 11.4 0.1 0.25 11.4 0.1 5.0 6 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 OWF52546.1 - 0.29 10.7 13.1 0.044 13.3 6.8 2.7 3 0 0 3 3 3 0 fzo-like conserved region ING PF12998.7 OWF52546.1 - 0.33 11.6 0.0 0.33 11.6 0.0 4.0 4 1 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding DUF812 PF05667.11 OWF52546.1 - 0.33 9.8 10.4 0.26 10.1 8.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ZapB PF06005.12 OWF52546.1 - 0.76 10.3 6.9 5.4 7.5 6.9 2.6 1 0 0 1 1 1 0 Cell division protein ZapB zf-C4H2 PF10146.9 OWF52546.1 - 2.5 8.3 10.1 0.33 11.2 2.7 2.9 4 0 0 4 4 4 0 Zinc finger-containing protein DUF1664 PF07889.12 OWF52546.1 - 4.1 7.5 17.3 0.93 9.5 6.5 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) MatE PF01554.18 OWF52547.1 - 2.1e-53 180.3 39.2 1.3e-28 99.7 12.9 2.9 3 0 0 3 3 3 2 MatE DUF4856 PF16148.5 OWF52547.1 - 0.56 9.1 1.5 0.86 8.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4856) Ribosomal_S17 PF00366.20 OWF52548.1 - 0.00032 20.8 0.2 0.00043 20.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Snf7 PF03357.21 OWF52549.1 - 2.5e-11 43.5 18.5 2.5e-11 43.5 18.5 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 OWF52549.1 - 0.015 15.3 6.1 0.023 14.6 6.1 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway ANAPC4 PF12896.7 OWF52549.1 - 0.032 13.7 0.3 0.061 12.8 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Collagen_mid PF15984.5 OWF52549.1 - 0.054 13.2 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region Flagellin_N PF00669.20 OWF52549.1 - 0.43 10.7 8.2 0.1 12.7 2.4 2.3 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region GrpE PF01025.19 OWF52549.1 - 0.64 9.7 13.7 0.11 12.1 8.5 2.1 1 1 1 2 2 2 0 GrpE YusW PF14039.6 OWF52549.1 - 1.8 9.1 10.3 4 8.0 2.1 2.9 1 1 1 3 3 3 0 YusW-like protein Adaptin_binding PF10199.9 OWF52549.1 - 3.6 8.2 10.0 5.2e+02 1.2 10.0 2.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Ank_2 PF12796.7 OWF52550.1 - 9.9e-33 112.6 0.3 2.9e-16 59.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF52550.1 - 1.4e-27 94.9 5.4 1e-06 28.9 0.1 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OWF52550.1 - 9.9e-26 89.8 13.6 4.8e-10 39.8 0.2 6.4 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF52550.1 - 4.8e-23 78.8 2.9 1.9e-06 27.8 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OWF52550.1 - 1.1e-17 63.9 5.1 7.2e-09 35.7 0.2 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF52550.1 - 3.8e-08 33.5 0.0 8.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 SOCS box Transglut_N PF00868.20 OWF52551.1 - 0.17 12.2 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase family LPMO_10 PF03067.15 OWF52552.1 - 0.0021 18.7 0.0 0.0037 17.9 0.0 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GPI-anchored PF10342.9 OWF52552.1 - 0.042 14.6 0.1 0.061 14.1 0.1 1.1 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2282 PF10048.9 OWF52552.1 - 0.1 12.6 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) HSF_DNA-bind PF00447.17 OWF52553.1 - 2.8e-21 75.9 0.2 6.2e-21 74.8 0.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding SpoU_methylas_C PF12105.8 OWF52553.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal DAO PF01266.24 OWF52554.1 - 1.7e-20 73.9 0.0 3e-20 73.1 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF52554.1 - 0.007 15.6 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OWF52554.1 - 0.013 14.6 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain hSac2 PF12456.8 OWF52554.1 - 0.035 13.8 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Inositol phosphatase AlaDh_PNT_C PF01262.21 OWF52554.1 - 0.038 13.3 1.1 0.11 11.7 1.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 OWF52554.1 - 0.056 13.0 0.3 0.086 12.4 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 OWF52554.1 - 0.066 12.7 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 OWF52554.1 - 0.1 11.8 0.3 0.16 11.2 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF52555.1 - 1.7e-33 116.7 0.0 2.5e-33 116.1 0.0 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OWF52555.1 - 0.0018 17.4 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OWF52555.1 - 0.0089 15.3 0.3 0.014 14.6 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OWF52555.1 - 0.011 14.9 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF52555.1 - 0.062 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OWF52555.1 - 0.099 13.2 0.2 0.34 11.5 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_pol_E_B PF04042.16 OWF52555.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DAO PF01266.24 OWF52556.1 - 9.4e-32 110.9 0.0 1.1e-31 110.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OWF52556.1 - 0.0058 15.8 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OWF52556.1 - 0.0068 15.7 0.5 0.013 14.7 0.5 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OWF52556.1 - 0.012 14.9 0.3 0.22 10.7 0.4 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF52556.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OWF52556.1 - 0.17 12.1 0.5 22 5.3 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 OWF52557.1 - 4.4e-38 131.8 0.0 5.1e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OWF52557.1 - 0.016 15.8 0.2 0.068 13.7 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF52557.1 - 0.017 14.3 0.1 0.037 13.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RuvA_N PF01330.21 OWF52558.1 - 0.0027 17.8 16.3 16 5.7 0.3 7.3 1 1 4 5 5 5 1 RuvA N terminal domain DUF4573 PF15140.6 OWF52558.1 - 0.014 15.2 10.2 0.03 14.1 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4573) DUF4464 PF14713.6 OWF52558.1 - 0.041 13.4 1.2 15 5.1 0.1 3.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4464) DUF3664 PF12406.8 OWF52558.1 - 0.21 12.2 14.5 17 6.1 1.5 4.5 1 1 3 4 4 4 0 Surface protein THEG PF14912.6 OWF52558.1 - 0.69 10.4 11.8 5.1 7.6 0.5 5.5 1 1 2 3 3 3 0 Testicular haploid expressed repeat AAT PF03417.16 OWF52558.1 - 0.74 9.5 7.7 40 3.8 5.1 3.9 1 1 1 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Tricorn_PDZ PF14685.6 OWF52558.1 - 1.7 8.7 10.0 55 3.8 0.1 4.4 1 1 5 6 6 6 0 Tricorn protease PDZ domain Zap1_zf2 PF18217.1 OWF52558.1 - 8.3 6.5 5.7 2e+02 2.1 0.1 4.1 3 0 0 3 3 3 0 Zap1 zinc finger 2 CARMIL_C PF16000.5 OWF52559.1 - 1.4e-37 130.0 23.1 1.4e-37 130.0 23.1 3.2 2 2 2 4 4 4 1 CARMIL C-terminus LRR_6 PF13516.6 OWF52559.1 - 7.1e-09 35.0 26.6 0.17 12.0 0.1 10.5 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 OWF52559.1 - 0.0048 17.2 19.0 4.3 8.3 0.7 8.4 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_4 PF12799.7 OWF52559.1 - 0.084 13.3 31.2 0.13 12.7 2.2 7.0 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) Thioredoxin PF00085.20 OWF52560.1 - 1.1e-24 86.4 0.0 8.8e-24 83.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 OWF52560.1 - 9e-20 71.4 2.0 2.6e-15 56.8 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OWF52560.1 - 1.3e-05 25.6 0.2 0.00024 21.5 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OWF52560.1 - 0.013 15.6 0.0 0.044 14.0 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 OWF52560.1 - 0.13 12.6 0.0 2.4 8.6 0.0 2.8 2 1 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 OWF52560.1 - 0.21 10.9 1.8 0.3 10.4 0.0 2.1 4 0 0 4 4 4 0 OST3 / OST6 family, transporter family Prefoldin_2 PF01920.20 OWF52562.1 - 1.6e-15 57.0 9.0 3.9e-15 55.7 9.0 1.6 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 OWF52562.1 - 0.17 11.8 7.7 0.63 10.0 7.7 1.8 1 1 0 1 1 1 0 Prefoldin subunit APG6_N PF17675.1 OWF52562.1 - 0.29 11.7 11.7 0.31 11.6 3.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region FAM167 PF11652.8 OWF52562.1 - 2.5 8.6 6.6 0.58 10.7 1.1 2.3 2 1 0 2 2 2 0 FAM167 KxDL PF10241.9 OWF52562.1 - 3 8.2 9.4 0.45 10.8 0.4 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein zf-C2H2 PF00096.26 OWF52563.1 - 2.9e-15 55.8 75.4 5e-05 23.5 1.5 9.7 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF52563.1 - 2.4e-12 46.6 72.3 0.016 16.0 0.5 9.6 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF52563.1 - 4e-06 27.0 60.5 0.00079 19.7 0.6 8.8 10 0 0 10 10 10 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF52563.1 - 0.00038 20.1 36.7 0.0027 17.4 3.7 6.4 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OWF52563.1 - 0.004 17.1 6.2 0.021 14.8 1.4 6.1 6 0 0 6 6 6 2 C2H2-type zinc finger ADK_lid PF05191.14 OWF52563.1 - 0.011 15.7 0.8 0.011 15.7 0.8 3.4 4 0 0 4 4 4 0 Adenylate kinase, active site lid GAGA PF09237.11 OWF52563.1 - 0.026 14.3 3.5 2.9 7.8 0.1 3.1 2 0 0 2 2 2 0 GAGA factor Elf1 PF05129.13 OWF52563.1 - 0.03 14.4 38.9 1.7 8.8 5.2 6.7 4 1 2 6 6 6 0 Transcription elongation factor Elf1 like Rubredoxin PF00301.20 OWF52563.1 - 0.7 10.0 0.0 0.7 10.0 0.0 5.2 7 0 0 7 7 7 0 Rubredoxin YlbD_coat PF14071.6 OWF52563.1 - 4.4 7.6 6.9 0.95 9.7 2.3 2.2 2 0 0 2 2 2 0 Putative coat protein Prokineticin PF06607.11 OWF52564.1 - 0.05 13.9 0.4 0.069 13.5 0.2 1.4 1 1 0 1 1 1 0 Prokineticin Attacin_C PF03769.15 OWF52567.1 - 1.2e-05 25.6 4.1 5.7 7.2 0.1 6.3 3 2 3 7 7 7 3 Attacin, C-terminal region RNA_pol_Rpb8 PF03870.15 OWF52568.1 - 0.082 13.1 3.8 43 4.3 0.1 4.6 2 2 3 6 6 6 0 RNA polymerase Rpb8 RPN5_C PF18098.1 OWF52568.1 - 0.16 12.1 0.2 2.1e+02 2.2 0.0 4.7 5 1 1 6 6 6 0 26S proteasome regulatory subunit RPN5 C-terminal domain zf-C2H2 PF00096.26 OWF52569.1 - 5.4e-28 95.9 68.7 0.00032 21.0 1.0 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF52569.1 - 4.8e-23 80.5 54.9 3e-05 24.2 1.5 9.6 8 1 1 9 9 9 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF52569.1 - 1.1e-15 56.9 66.2 0.0018 18.9 0.9 10.6 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF52569.1 - 0.00033 20.9 28.6 0.0062 16.8 2.9 5.7 2 1 5 7 7 7 4 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 OWF52569.1 - 0.016 15.2 0.0 0.016 15.2 0.0 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger Phage_head_fibr PF11133.8 OWF52569.1 - 0.016 14.6 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Head fiber protein Mannosidase_ig PF17786.1 OWF52569.1 - 0.094 13.3 0.1 0.3 11.7 0.1 1.9 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain zf-C2H2_aberr PF17017.5 OWF52569.1 - 1.1 9.3 38.5 3 8.0 0.8 7.5 1 1 3 7 7 7 0 Aberrant zinc-finger zf-C2H2_9 PF16293.5 OWF52569.1 - 3.7 7.5 5.0 50 3.9 0.1 4.3 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 OWF52569.1 - 5.3 7.6 18.6 18 5.9 0.0 6.2 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DUF5565 PF17720.1 OWF52570.1 - 1.6e-133 444.6 0.2 2e-133 444.2 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5565) Kelch_4 PF13418.6 OWF52572.1 - 1.6e-34 117.7 15.3 9.4e-09 35.2 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF52572.1 - 6.4e-20 70.7 7.9 0.0081 16.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 OWF52572.1 - 1.5e-15 56.5 10.7 0.0007 19.1 0.0 6.4 6 2 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OWF52572.1 - 1e-13 51.2 15.0 0.055 13.8 0.0 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF52572.1 - 1.1e-13 50.9 8.5 0.093 13.1 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OWF52572.1 - 3e-11 42.8 10.2 3.6e-05 23.6 0.0 6.8 7 0 0 7 7 7 2 Kelch motif CutA1 PF03091.15 OWF52573.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Palm_thioest PF02089.15 OWF52574.1 - 1.1e-60 205.5 0.0 1.2e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 OWF52574.1 - 0.0049 16.4 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OWF52574.1 - 0.01 15.5 0.1 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein 7tm_1 PF00001.21 OWF52575.1 - 2.2e-48 164.9 16.4 3.1e-48 164.4 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF52575.1 - 2.1e-13 50.5 20.0 2.1e-13 50.5 20.0 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF52575.1 - 3.4e-09 36.5 12.3 4.5e-09 36.1 12.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 OWF52575.1 - 4.2e-07 29.6 18.0 9.5e-07 28.5 17.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PGA2 PF07543.12 OWF52575.1 - 0.018 15.0 0.9 0.031 14.3 0.9 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Peptidase_S49_N PF08496.10 OWF52575.1 - 0.07 13.2 3.6 0.17 11.9 3.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SARAF PF06682.12 OWF52575.1 - 0.13 11.9 1.6 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF485 PF04341.12 OWF52575.1 - 0.31 11.0 5.1 1.9 8.5 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function, DUF485 DUF4519 PF15012.6 OWF52575.1 - 2.5 8.3 13.0 0.51 10.5 1.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) TMEMspv1-c74-12 PF11044.8 OWF52575.1 - 3.9 7.5 10.7 0.17 11.9 3.4 2.6 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein EphA2_TM PF14575.6 OWF52575.1 - 7 7.6 7.6 0.74 10.7 0.1 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RRP14 PF15459.6 OWF52575.1 - 9.2 7.0 11.0 23 5.7 11.0 1.7 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Prefoldin_2 PF01920.20 OWF52576.1 - 1.2e-23 83.0 14.9 1.6e-23 82.6 14.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit DHHW PF14286.6 OWF52576.1 - 0.0018 17.6 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 DHHW protein YfiO PF13525.6 OWF52576.1 - 0.016 15.0 1.9 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Outer membrane lipoprotein Rx_N PF18052.1 OWF52576.1 - 0.016 15.5 4.7 0.017 15.4 0.2 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Fib_alpha PF08702.10 OWF52576.1 - 0.035 14.3 2.2 0.035 14.3 2.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Bcr-Abl_Oligo PF09036.10 OWF52576.1 - 0.048 13.7 0.3 0.048 13.7 0.3 2.3 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Vac_Fusion PF02346.16 OWF52576.1 - 0.07 12.8 3.3 0.57 9.8 0.2 2.8 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 XhlA PF10779.9 OWF52576.1 - 0.082 13.1 1.0 0.082 13.1 1.0 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Spc7 PF08317.11 OWF52576.1 - 0.082 11.8 12.8 0.1 11.4 12.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 OWF52576.1 - 0.11 12.3 12.2 0.8 9.5 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4201 PF13870.6 OWF52576.1 - 0.11 12.2 12.1 0.54 10.0 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DHR10 PF18595.1 OWF52576.1 - 0.13 12.3 16.1 1 9.4 3.9 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 OWF52576.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.5 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 OWF52576.1 - 0.18 11.9 13.6 0.18 11.9 3.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin PF02996.17 OWF52576.1 - 0.24 11.3 14.3 0.49 10.3 2.8 3.0 1 1 1 2 2 2 0 Prefoldin subunit DUF4298 PF14131.6 OWF52576.1 - 0.35 10.8 9.3 0.41 10.6 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF1664 PF07889.12 OWF52576.1 - 0.39 10.8 9.0 0.33 11.0 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 OWF52576.1 - 0.39 10.1 15.0 1 8.7 3.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SOGA PF11365.8 OWF52576.1 - 0.56 11.4 9.4 1.3 10.2 1.8 2.2 2 0 0 2 2 2 0 Protein SOGA DivIVA PF05103.13 OWF52576.1 - 0.56 10.3 13.7 0.63 10.1 3.8 2.2 1 1 1 2 2 2 0 DivIVA protein YscO PF07321.12 OWF52576.1 - 0.61 10.0 14.8 0.22 11.5 4.1 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO Laminin_II PF06009.12 OWF52576.1 - 0.71 9.9 7.9 0.88 9.6 1.3 2.1 2 0 0 2 2 2 0 Laminin Domain II Med4 PF10018.9 OWF52576.1 - 0.76 9.4 12.4 0.12 12.1 2.6 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF5344 PF17279.2 OWF52576.1 - 3 8.5 11.2 0.67 10.6 2.9 2.6 1 1 0 2 2 2 0 Family of unknown function (DUF5344) BLOC1_2 PF10046.9 OWF52576.1 - 3.2 8.1 10.6 7.7 6.9 1.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AP1AR PF15745.5 OWF52576.1 - 3.8 7.1 9.0 4.5 6.8 9.0 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein RasGAP_C PF03836.15 OWF52576.1 - 4.4 7.5 13.7 0.13 12.4 4.2 2.1 1 1 1 2 2 2 0 RasGAP C-terminus DUF3450 PF11932.8 OWF52576.1 - 5.9 6.1 16.5 1.4 8.1 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 OWF52576.1 - 6.3 7.3 14.8 86 3.7 14.8 2.1 1 1 0 1 1 1 0 Cell division protein ZapB SURF1 PF02104.15 OWF52577.1 - 1.5e-21 77.4 0.0 2.1e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family I-set PF07679.16 OWF52578.1 - 0 1333.4 0.0 1.3e-17 63.7 0.1 28.4 27 1 1 28 28 28 28 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF52578.1 - 0 1197.3 47.2 2.4e-16 60.1 0.1 28.8 27 1 1 28 28 28 28 Immunoglobulin domain Ig_2 PF13895.6 OWF52578.1 - 1.7e-258 835.8 26.6 4.2e-12 46.2 0.0 29.1 27 2 2 29 29 29 27 Immunoglobulin domain ig PF00047.25 OWF52578.1 - 3.3e-220 713.0 0.5 7.9e-10 38.8 0.1 28.7 28 0 0 28 28 28 26 Immunoglobulin domain V-set PF07686.17 OWF52578.1 - 8.4e-80 264.1 63.0 0.0032 17.6 0.1 46.5 30 22 1 32 32 32 15 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF52578.1 - 5.9e-74 244.2 24.5 0.057 13.5 0.0 26.4 26 1 1 27 27 26 22 CD80-like C2-set immunoglobulin domain EGF_CA PF07645.15 OWF52578.1 - 1.6e-63 210.7 152.2 8.2e-10 38.7 9.5 11.9 11 0 0 11 11 9 9 Calcium-binding EGF domain TSP_1 PF00090.19 OWF52578.1 - 7.6e-59 195.7 111.9 1.8e-13 50.5 9.6 8.0 7 0 0 7 7 6 6 Thrombospondin type 1 domain cEGF PF12662.7 OWF52578.1 - 2.1e-42 142.6 80.7 1.1e-08 34.8 0.5 12.1 11 0 0 11 11 10 8 Complement Clr-like EGF-like Ig_6 PF18452.1 OWF52578.1 - 5e-32 109.2 8.9 0.36 10.4 0.0 22.0 26 0 0 26 26 23 5 Immunoglobulin domain Receptor_2B4 PF11465.8 OWF52578.1 - 1.6e-21 76.5 0.0 0.029 14.6 0.0 14.8 18 0 0 18 18 17 3 Natural killer cell receptor 2B4 Ig_C17orf99 PF17736.1 OWF52578.1 - 1.1e-19 70.3 0.2 0.03 14.4 0.0 14.5 17 0 0 17 17 15 3 C17orf99 Ig domain Izumo-Ig PF16706.5 OWF52578.1 - 2.9e-18 65.7 7.3 0.59 10.2 0.0 17.7 21 0 0 21 21 20 1 Izumo-like Immunoglobulin domain FXa_inhibition PF14670.6 OWF52578.1 - 3.1e-18 65.8 159.6 5.3e-07 29.8 9.7 12.5 12 1 1 13 13 10 7 Coagulation Factor Xa inhibitory site V-set_CD47 PF08204.11 OWF52578.1 - 1.6e-09 37.8 10.7 0.097 12.7 0.0 12.3 13 2 2 15 15 12 1 CD47 immunoglobulin-like domain BiPBP_C PF06832.12 OWF52578.1 - 7.2e-07 29.2 0.0 18 5.5 0.0 9.3 13 0 0 13 13 12 0 Penicillin-Binding Protein C-terminus Family EGF PF00008.27 OWF52578.1 - 7.3e-05 23.0 118.9 0.0058 16.9 6.7 11.0 9 0 0 9 9 9 6 EGF-like domain EGF_3 PF12947.7 OWF52578.1 - 0.00011 22.3 125.2 0.0011 19.1 10.5 10.6 9 1 0 9 9 9 3 EGF domain G2F PF07474.12 OWF52578.1 - 0.0018 18.0 0.0 0.22 11.3 0.0 2.5 1 1 1 2 2 2 1 G2F domain DUF3954 PF13128.6 OWF52578.1 - 0.98 9.3 13.6 13 5.7 0.1 6.7 6 0 0 6 6 6 0 Protein of unknown function (DUF3954) Pentapeptide_2 PF01469.18 OWF52579.1 - 0.01 15.7 1.3 0.01 15.7 1.3 1.9 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) SPX PF03105.19 OWF52579.1 - 3.2 7.6 15.8 0.42 10.5 5.8 2.3 2 0 0 2 2 2 0 SPX domain Pro_isomerase PF00160.21 OWF52581.1 - 2.4e-42 144.9 0.2 3.6e-42 144.3 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ROQ_II PF18386.1 OWF52583.1 - 1.1e-31 108.3 0.2 2.3e-31 107.4 0.2 1.5 1 0 0 1 1 1 1 Roquin II domain zf-RING_UBOX PF13445.6 OWF52583.1 - 1.4e-06 28.2 7.6 3.4e-06 27.0 7.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF52583.1 - 1.7e-06 27.9 5.4 3.7e-06 26.8 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH PF00642.24 OWF52583.1 - 1.4e-05 24.9 0.8 3.3e-05 23.7 0.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 OWF52583.1 - 3.2e-05 24.2 5.3 7.8e-05 22.9 5.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 OWF52583.1 - 3.9e-05 23.6 0.9 8.6e-05 22.5 0.9 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_3 PF13920.6 OWF52583.1 - 7.5e-05 22.5 3.2 0.00015 21.6 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF52583.1 - 0.00041 20.2 6.4 0.0009 19.1 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF52583.1 - 0.0042 16.9 5.9 0.011 15.5 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF52583.1 - 0.0057 16.8 6.5 0.0057 16.8 6.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF52583.1 - 0.012 15.4 11.9 0.028 14.3 7.3 2.6 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 PaaA_PaaC PF05138.12 OWF52583.1 - 0.044 12.9 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein zf-RING_4 PF14570.6 OWF52583.1 - 1.2 9.0 4.7 2.7 7.9 4.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OWF52583.1 - 6.8 6.9 10.2 0.47 10.6 4.0 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Collagen_mid PF15984.5 OWF52584.1 - 8.2e-05 22.4 0.0 0.76 9.5 0.0 3.9 2 2 2 4 4 4 1 Bacterial collagen, middle region Phage_NinH PF06322.11 OWF52584.1 - 0.00012 21.9 11.8 5 7.1 0.0 8.7 2 2 9 11 11 11 1 Phage NinH protein Dicty_spore_N PF04562.12 OWF52584.1 - 0.0032 18.2 39.7 0.98 10.1 11.3 3.6 1 1 3 4 4 4 3 Dictyostelium spore coat protein, N terminus DUF5046 PF16465.5 OWF52584.1 - 0.0052 16.3 7.4 0.51 9.7 0.1 3.5 1 1 2 4 4 4 2 Domain of unknown function (DUF5046) D_CNTX PF17492.2 OWF52584.1 - 0.052 13.7 55.5 1.3 9.3 1.5 10.3 1 1 9 10 10 10 0 Delta Ctenitoxins zf-C3HC4_3 PF13920.6 OWF52585.1 - 1.5e-12 47.2 12.1 3e-12 46.2 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.6 OWF52585.1 - 1.1e-10 41.1 18.9 2.6e-05 23.9 2.6 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OWF52585.1 - 7.4e-10 38.9 19.1 6.1e-06 26.5 3.4 4.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) SAM_1 PF00536.30 OWF52585.1 - 9e-10 38.9 0.9 2.1e-09 37.7 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF52585.1 - 1.8e-08 34.4 0.8 5.3e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Prok-RING_4 PF14447.6 OWF52585.1 - 0.0003 20.6 12.4 0.00067 19.5 12.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 IGR PF09597.10 OWF52585.1 - 0.011 15.9 0.0 0.043 13.9 0.0 2.1 1 0 0 1 1 1 0 IGR protein motif LRR_1 PF00560.33 OWF52585.1 - 0.011 16.2 15.4 0.38 11.5 0.5 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 OWF52585.1 - 0.9 9.8 10.8 6.8 7.0 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat zf-RING_5 PF14634.6 OWF52585.1 - 1.4 9.0 12.0 3 7.9 12.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Lectin_C PF00059.21 OWF52586.1 - 4.3e-12 46.7 0.2 8.9e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain WW PF00397.26 OWF52587.1 - 1.3e-10 41.2 1.3 3.3e-10 39.8 1.3 1.8 1 0 0 1 1 1 1 WW domain XylR_N PF06505.11 OWF52587.1 - 0.044 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Activator of aromatic catabolism 7tm_1 PF00001.21 OWF52588.1 - 5.6e-23 81.6 14.9 7e-23 81.3 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HSP70 PF00012.20 OWF52589.1 - 1.8e-252 838.9 8.3 2e-252 838.7 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF52589.1 - 3.3e-16 59.0 1.2 7.1e-15 54.6 1.2 2.1 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 OWF52589.1 - 0.00011 22.6 4.9 0.081 13.3 0.1 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OWF52589.1 - 0.033 13.4 2.1 0.09 12.0 0.1 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 OWF52589.1 - 0.034 13.4 0.9 2.1 7.5 0.1 2.7 1 1 1 2 2 2 0 StbA protein DDR PF08841.10 OWF52589.1 - 0.061 12.3 2.0 0.25 10.3 2.0 2.0 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Spt46 PF17734.1 OWF52589.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 FGGY_C PF02782.16 OWF52589.1 - 0.18 11.5 0.0 0.53 10.0 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 OWF52590.1 - 4.2e-264 877.3 12.3 4.8e-264 877.1 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OWF52590.1 - 7.9e-17 61.1 1.3 3.4e-15 55.7 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OWF52590.1 - 0.00051 20.4 5.1 0.24 11.8 0.1 3.4 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OWF52590.1 - 0.0029 16.9 2.1 0.028 13.7 0.1 3.0 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DUF4624 PF15417.6 OWF52590.1 - 0.032 14.1 0.2 0.22 11.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4624) CENP-Q PF13094.6 OWF52590.1 - 0.24 11.6 7.4 2.8 8.1 1.6 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Glyco_hydro_47 PF01532.20 OWF52591.1 - 6.2e-135 450.6 0.0 8.3e-135 450.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PIN_4 PF13638.6 OWF52592.1 - 2.5e-30 105.5 1.0 9.3e-30 103.6 0.1 2.5 2 0 0 2 2 2 1 PIN domain WW PF00397.26 OWF52592.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 OWF52592.1 - 0.025 14.9 0.0 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain PIN_9 PF18477.1 OWF52592.1 - 0.032 14.5 0.1 0.13 12.6 0.1 2.0 1 0 0 1 1 1 0 PIN like domain PIN_8 PF18476.1 OWF52592.1 - 0.092 12.6 0.1 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 PIN like domain FAM219A PF15260.6 OWF52592.1 - 0.25 11.7 3.0 6.1 7.2 0.1 2.9 1 1 1 2 2 2 0 Protein family FAM219A Golgin_A5 PF09787.9 OWF52593.1 - 0.021 14.3 4.4 0.025 14.1 4.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 OWF52593.1 - 0.032 13.6 1.1 0.039 13.3 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 OWF52593.1 - 0.53 10.7 4.0 1.9 8.9 0.2 2.3 2 1 0 2 2 2 0 Csm1 N-terminal domain Pyridoxal_deC PF00282.19 OWF52594.1 - 3.4e-155 516.4 0.0 4e-155 516.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OWF52594.1 - 0.00058 19.2 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Bromodomain PF00439.25 OWF52595.1 - 8.6e-41 137.9 2.3 1.1e-19 70.3 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 OWF52595.1 - 2.3e-27 94.9 0.1 2.3e-27 94.9 0.1 2.7 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.5 OWF52595.1 - 9e-15 54.0 12.7 9e-15 54.0 12.7 2.9 3 0 0 3 3 3 1 C-terminal domain of bromodomain protein 4 TTRAP PF14203.6 OWF52595.1 - 0.14 12.1 5.1 0.46 10.5 5.1 1.9 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein WD40 PF00400.32 OWF52596.1 - 3.9e-64 211.0 17.6 8.9e-10 39.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF52596.1 - 1.3e-26 92.8 1.1 0.00029 21.1 0.0 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF52596.1 - 1.3e-14 53.8 4.2 0.0042 15.8 0.1 4.8 1 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 OWF52596.1 - 8.2e-13 48.7 0.0 1.9e-06 27.9 0.0 3.7 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OWF52596.1 - 2.3e-06 27.1 0.1 0.0026 17.1 0.0 2.9 1 1 3 4 4 4 3 WD40-like domain PALB2_WD40 PF16756.5 OWF52596.1 - 2.7e-06 26.5 1.6 2.3 7.1 0.0 4.2 1 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 OWF52596.1 - 2.9e-05 22.6 0.0 0.019 13.3 0.0 2.8 1 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 OWF52596.1 - 6.3e-05 22.1 6.1 0.25 10.3 1.2 4.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 OWF52596.1 - 0.011 14.2 0.0 0.34 9.4 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.10 OWF52596.1 - 0.013 14.6 0.0 0.27 10.3 0.0 2.5 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Hira PF07569.11 OWF52596.1 - 0.035 13.8 1.1 30 4.3 0.0 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split Kelch_6 PF13964.6 OWF52596.1 - 0.12 12.8 0.8 2.7 8.4 0.1 3.0 2 1 0 2 2 2 0 Kelch motif SURF4 PF02077.15 OWF52597.1 - 2.5e-121 404.4 4.6 2.8e-121 404.2 4.6 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 OWF52597.1 - 1.2e-17 64.4 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF4808 PF16066.5 OWF52597.1 - 0.17 12.5 0.6 0.29 11.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) SAGA-Tad1 PF12767.7 OWF52598.1 - 3.4e-18 66.3 3.1 1.1e-12 48.2 1.1 3.6 2 2 0 3 3 3 2 Transcriptional regulator of RNA polII, SAGA, subunit EF-hand_1 PF00036.32 OWF52599.1 - 5e-13 47.6 12.6 0.0032 16.9 0.2 4.2 2 2 2 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF52599.1 - 2.9e-10 39.2 14.4 0.00043 19.7 0.8 4.2 3 1 1 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF52599.1 - 3.9e-10 40.0 10.9 0.052 14.0 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF52599.1 - 7.4e-10 38.0 13.8 0.019 14.9 0.5 4.2 2 2 2 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF52599.1 - 6.2e-09 35.6 6.2 0.035 14.0 0.1 3.6 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF52599.1 - 0.0033 17.7 2.5 6.8 7.1 0.2 3.2 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OWF52599.1 - 0.014 15.4 0.4 3.7 7.4 0.1 2.3 2 1 0 2 2 2 0 Caleosin related protein EF-hand_10 PF14788.6 OWF52599.1 - 0.15 12.0 0.2 21 5.0 0.0 2.4 2 0 0 2 2 2 0 EF hand Myosin-VI_CBD PF16521.5 OWF52599.1 - 0.18 11.8 0.0 4.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Myosin VI cargo binding domain Dockerin_1 PF00404.18 OWF52599.1 - 0.53 10.5 9.6 1.4 9.2 2.3 3.6 1 1 3 4 4 4 0 Dockerin type I domain EF-hand_8 PF13833.6 OWF52600.1 - 8.3e-13 48.0 1.8 5.8e-05 22.9 0.6 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF52600.1 - 1.2e-12 46.4 7.0 0.00021 20.6 2.0 4.3 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF52600.1 - 8.3e-10 37.8 8.3 0.02 14.8 0.8 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OWF52600.1 - 1.4e-08 35.0 6.4 0.0013 19.1 6.4 3.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF52600.1 - 1.1e-07 31.1 4.2 0.02 14.3 1.7 4.2 3 1 1 4 4 4 2 EF hand Prenyltrans PF00432.21 OWF52601.1 - 8.9e-68 223.7 6.5 8.8e-16 57.4 0.0 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OWF52601.1 - 4.5e-05 22.7 0.0 0.00013 21.2 0.0 1.7 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OWF52601.1 - 0.064 12.4 0.0 5.6 6.0 0.0 2.8 2 1 1 3 3 3 0 Squalene-hopene cyclase N-terminal domain MFS_1 PF07690.16 OWF52602.1 - 9.3e-33 113.6 42.3 6.4e-27 94.4 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 OWF52602.1 - 0.24 11.2 5.5 0.66 9.8 0.3 3.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 OWF52603.1 - 8.5e-34 117.0 16.6 2.7e-28 98.9 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 OWF52606.1 - 1.8e-07 31.2 0.3 3.5e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 OWF52606.1 - 5.1e-05 23.0 8.6 9.5e-05 22.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OWF52606.1 - 0.00013 22.2 0.4 0.00031 20.9 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cript PF10235.9 OWF52606.1 - 0.042 14.4 0.5 0.088 13.4 0.5 1.6 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT HLH PF00010.26 OWF52607.1 - 5.2e-09 35.9 0.1 1.1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Auxin_repressed PF05564.12 OWF52607.1 - 0.03 15.0 0.5 0.03 15.0 0.5 2.1 2 0 0 2 2 2 0 Dormancy/auxin associated protein Ank_4 PF13637.6 OWF52608.1 - 5e-17 62.0 0.8 2e-11 44.2 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF52608.1 - 1.5e-16 60.7 0.1 1.8e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF52608.1 - 8.5e-14 51.4 2.5 7.2e-11 42.1 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF52608.1 - 6.9e-13 47.5 0.0 7.3e-05 22.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OWF52608.1 - 1.7e-09 37.7 0.5 0.0029 18.0 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat DUF1030 PF06270.11 OWF52609.1 - 2.2 8.1 6.0 3.6 7.4 0.2 3.8 2 1 3 5 5 5 0 Protein of unknown function (DUF1030) TOH_N PF12549.8 OWF52610.1 - 0.0018 18.1 4.5 4.8e+02 0.8 0.0 7.7 9 0 0 9 9 9 0 Tyrosine hydroxylase N terminal DUF4741 PF15897.5 OWF52610.1 - 0.002 17.9 1.9 11 5.8 0.1 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4741) BTB PF00651.31 OWF52611.1 - 5.5e-27 94.2 1.4 1.1e-26 93.3 0.5 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF52611.1 - 7.5e-13 48.5 0.1 1.6e-10 41.0 0.1 3.0 2 1 0 2 2 2 2 BTB And C-terminal Kelch Longin PF13774.6 OWF52612.1 - 1.9e-24 85.5 0.1 3.2e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OWF52612.1 - 1.8e-18 66.1 0.1 3e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Mt_ATP-synt_B PF05405.14 OWF52612.1 - 0.0055 16.4 0.1 0.019 14.6 0.1 1.8 1 1 1 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sec16_C PF12931.7 OWF52613.1 - 1.5e-47 162.7 0.0 2.8e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OWF52613.1 - 1.3e-10 41.9 0.0 7.1e-10 39.5 0.0 2.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region 7tm_1 PF00001.21 OWF52614.1 - 2.7e-17 63.0 24.3 3.7e-17 62.5 24.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF52614.1 - 5e-12 45.7 28.9 7e-12 45.2 28.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw NAP PF00956.18 OWF52615.1 - 2.5e-35 122.0 14.9 4.9e-30 104.6 3.8 3.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 OWF52615.1 - 0.0015 18.4 2.7 0.0031 17.5 2.7 1.5 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF4407 PF14362.6 OWF52615.1 - 0.025 13.9 2.6 0.037 13.4 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dynamin_N PF00350.23 OWF52615.1 - 0.076 13.1 0.6 0.11 12.6 0.6 1.3 1 0 0 1 1 1 0 Dynamin family Uds1 PF15456.6 OWF52615.1 - 0.1 12.8 2.5 0.22 11.7 2.5 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Pro-NT_NN PF07421.11 OWF52615.1 - 0.15 12.3 1.7 0.39 11.0 1.7 1.7 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor ATP-synt_B PF00430.18 OWF52615.1 - 0.22 11.6 6.8 0.37 10.9 6.8 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1492 PF07374.11 OWF52615.1 - 0.27 11.4 2.1 0.52 10.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) IFT20 PF14931.6 OWF52615.1 - 3.8 7.7 12.1 1.5 9.0 8.6 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Cu2_monooxygen PF01082.20 OWF52616.1 - 1.5e-25 89.9 0.3 4e-25 88.6 0.3 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF52616.1 - 7.3e-22 77.6 0.1 1.4e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monoox_C PF03712.15 OWF52617.1 - 1.8e-27 95.8 0.3 6.7e-27 93.9 0.2 2.1 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF52617.1 - 1.7e-17 63.9 0.2 3.3e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain TSP_3 PF02412.18 OWF52617.1 - 0.17 11.6 1.5 3.4 7.4 0.3 2.6 2 0 0 2 2 2 0 Thrombospondin type 3 repeat LRR_4 PF12799.7 OWF52619.1 - 1.2e-05 25.5 2.6 1.2e-05 25.5 2.6 1.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF52619.1 - 0.0001 22.0 0.8 0.0002 21.0 0.8 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 OWF52619.1 - 0.11 13.2 1.7 7.3 7.6 1.7 2.9 1 1 0 1 1 1 0 Leucine Rich Repeat Neur_chan_LBD PF02931.23 OWF52620.1 - 8.1e-40 136.6 0.6 1.2e-39 136.0 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52620.1 - 5.3e-15 56.1 12.1 2.1e-14 54.2 6.2 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ank_2 PF12796.7 OWF52622.1 - 7.6e-21 74.5 0.0 3e-12 46.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF52622.1 - 3.5e-19 66.9 0.0 0.007 16.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OWF52622.1 - 1.2e-12 47.8 0.0 0.059 13.7 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF52622.1 - 3.8e-12 46.1 0.0 0.28 11.7 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OWF52622.1 - 1.2e-09 38.5 0.0 0.067 13.8 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) GIT_SHD PF08518.11 OWF52622.1 - 9.4e-08 31.6 0.1 4.9 6.9 0.0 4.2 4 0 0 4 4 4 4 Spa2 homology domain (SHD) of GIT Transglut_N PF00868.20 OWF52622.1 - 4.8e-05 23.7 0.7 1.8 8.9 0.0 3.9 1 1 3 4 4 4 1 Transglutaminase family PRODH PF18327.1 OWF52622.1 - 0.01 16.0 0.2 55 4.1 0.0 3.3 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain AP_endonuc_2 PF01261.24 OWF52622.1 - 0.016 14.7 0.0 12 5.2 0.0 3.1 1 1 3 4 4 4 0 Xylose isomerase-like TIM barrel DUF1366 PF07104.11 OWF52622.1 - 0.018 14.7 0.0 4.5 7.0 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1366) Roc PF08477.13 OWF52622.1 - 0.024 14.9 0.0 0.19 12.0 0.0 2.2 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ephrin_rec_like PF07699.13 OWF52623.1 - 2.6e-123 401.7 352.7 1.6e-10 40.6 11.2 25.9 24 2 2 26 26 26 22 Putative ephrin-receptor like EGF PF00008.27 OWF52623.1 - 8e-27 93.2 241.1 6.6e-06 26.3 9.9 18.8 17 0 0 17 17 17 13 EGF-like domain Laminin_G_3 PF13385.6 OWF52623.1 - 1.1e-05 25.6 0.1 2.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 OWF52623.1 - 1.7e-05 25.2 19.5 0.00022 21.7 6.2 19.7 18 0 0 18 18 18 6 Human growth factor-like EGF EphA2_TM PF14575.6 OWF52623.1 - 0.012 16.5 0.0 0.035 15.0 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Laminin_G_2 PF02210.24 OWF52623.1 - 0.085 13.4 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Cluap1 PF10234.9 OWF52624.1 - 2.3e-119 397.7 10.5 3.4e-119 397.2 10.5 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.12 OWF52624.1 - 0.0028 17.3 0.1 0.0028 17.3 0.1 1.8 1 1 1 2 2 2 1 Secretion system effector C (SseC) like family Lebercilin PF15619.6 OWF52624.1 - 0.006 16.3 18.7 0.01 15.5 18.6 1.4 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HWE_HK PF07536.14 OWF52624.1 - 0.0099 16.6 1.6 0.31 11.8 0.1 2.7 2 1 0 2 2 2 1 HWE histidine kinase Ndc80_HEC PF03801.13 OWF52624.1 - 0.085 12.5 1.2 0.28 10.8 0.0 2.3 2 1 1 3 3 3 0 HEC/Ndc80p family DUF4320 PF14208.6 OWF52624.1 - 0.13 12.3 0.6 3.4 7.8 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) Bac_luciferase PF00296.20 OWF52624.1 - 0.27 10.6 0.4 0.44 9.9 0.4 1.3 1 0 0 1 1 1 0 Luciferase-like monooxygenase Fez1 PF06818.15 OWF52624.1 - 0.3 11.5 18.1 0.77 10.2 17.2 2.0 1 1 1 2 2 2 0 Fez1 YtxH PF12732.7 OWF52624.1 - 0.32 11.5 3.8 1.1 9.9 0.6 2.6 2 1 0 2 2 2 0 YtxH-like protein FadA PF09403.10 OWF52624.1 - 0.37 11.3 18.6 0.38 11.3 7.3 3.0 1 1 1 2 2 2 0 Adhesion protein FadA UPF0149 PF03695.13 OWF52624.1 - 0.6 10.4 2.7 1.5 9.1 1.5 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0149) DUF4407 PF14362.6 OWF52624.1 - 0.95 8.8 10.4 1.6 8.0 10.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 OWF52624.1 - 1.7 8.2 15.4 2.1 7.8 13.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FYVE_2 PF02318.16 OWF52624.1 - 2 8.7 7.8 0.12 12.6 1.5 2.2 2 1 2 4 4 3 0 FYVE-type zinc finger Exonuc_VII_L PF02601.15 OWF52624.1 - 2.8 7.4 13.4 6.1 6.3 13.4 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 OWF52624.1 - 3.3 6.9 13.4 0.27 10.4 2.2 2.3 1 1 1 2 2 2 0 TMPIT-like protein DUF1043 PF06295.12 OWF52624.1 - 3.6 7.6 11.4 4.3 7.4 1.3 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1043) ADIP PF11559.8 OWF52624.1 - 6.3 6.9 17.6 0.15 12.2 5.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SHMT PF00464.19 OWF52625.1 - 3.2e-200 664.8 0.0 3.8e-200 664.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 OWF52625.1 - 9.6e-08 31.6 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Neur PF00064.18 OWF52625.1 - 0.056 12.2 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Neuraminidase Ribosomal_L12 PF00542.19 OWF52626.1 - 1.5e-20 73.3 3.6 1.5e-20 73.3 3.6 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OWF52626.1 - 5.5e-13 48.4 1.9 5.5e-13 48.4 1.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Tma16 PF11176.8 OWF52627.1 - 6.8e-37 126.6 5.4 8.3e-37 126.3 5.4 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 PCNA_C PF02747.15 OWF52628.1 - 2e-61 205.8 0.0 3.5e-61 205.0 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 OWF52628.1 - 7.9e-57 190.4 1.2 7.9e-57 190.4 1.2 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 OWF52628.1 - 0.00026 20.6 0.2 0.00039 20.0 0.2 1.3 1 1 0 1 1 1 1 Rad9 EF-hand_6 PF13405.6 OWF52629.1 - 8.7e-16 56.4 4.3 3.4e-05 23.4 0.3 4.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OWF52629.1 - 1e-15 57.3 3.5 1.5e-07 31.1 0.0 5.0 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 OWF52629.1 - 8.7e-14 51.7 4.2 0.00036 20.9 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF52629.1 - 1.4e-13 49.4 11.2 1.2e-05 24.5 1.1 5.3 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 OWF52629.1 - 8.2e-11 40.9 6.3 1.7e-06 27.2 0.5 3.8 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 OWF52629.1 - 0.0004 20.3 0.2 0.54 10.2 0.1 2.8 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand TRM13 PF05206.14 OWF52629.1 - 0.064 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 Dockerin_1 PF00404.18 OWF52629.1 - 0.18 12.0 0.1 5.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Dockerin type I domain RRM_1 PF00076.22 OWF52630.1 - 2.6e-23 81.6 0.1 1.7e-09 37.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mob1_phocein PF03637.17 OWF52631.1 - 2.4e-82 275.0 0.2 3e-82 274.7 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Abhydro_lipase PF04083.16 OWF52632.1 - 1.3e-20 72.8 0.0 2.8e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OWF52632.1 - 3.4e-20 72.8 0.6 5.3e-14 52.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF52632.1 - 1.5e-06 27.7 0.0 0.001 18.4 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 OWF52632.1 - 0.1 11.1 0.1 0.57 8.6 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 OWF52633.1 - 1.2e-23 84.1 0.1 5.7e-23 81.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OWF52633.1 - 1.2e-19 69.6 0.0 2.3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 OWF52633.1 - 1e-07 31.5 0.0 7.5e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Histone PF00125.24 OWF52634.1 - 2.6e-19 69.9 0.0 3.1e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OWF52634.1 - 0.0056 16.9 0.0 0.0096 16.2 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 OWF52634.1 - 0.0075 16.0 0.2 0.018 14.8 0.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A RTP801_C PF07809.11 OWF52635.1 - 1.1e-32 112.4 0.0 2.2e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 RTP801 C-terminal region Collagen PF01391.18 OWF52636.1 - 5.7e-46 154.1 206.5 6.5e-07 29.0 28.4 8.6 2 2 4 6 6 6 5 Collagen triple helix repeat (20 copies) MFS_2 PF13347.6 OWF52637.1 - 4.9e-27 94.6 27.4 1.2e-26 93.3 27.4 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein COX6B PF02297.17 OWF52638.1 - 9.4e-14 51.4 1.3 1.4e-13 50.9 1.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Toxin_17 PF08086.11 OWF52638.1 - 0.078 13.3 4.6 0.16 12.3 4.6 1.5 1 0 0 1 1 1 0 Ergtoxin family CX9C PF16860.5 OWF52638.1 - 0.14 12.2 1.9 0.31 11.1 1.9 1.6 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF4457 PF14652.6 OWF52639.1 - 3.2e-204 677.3 1.0 3.1e-141 470.3 0.0 4.3 3 1 1 4 4 4 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OWF52639.1 - 3.9e-06 26.9 0.1 1.2 9.1 0.0 4.3 4 0 0 4 4 4 3 Sad1 / UNC-like C-terminal VWA_3_C PF18571.1 OWF52639.1 - 0.094 12.6 0.6 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain tRNA_int_end_N2 PF12928.7 OWF52640.1 - 6.4e-15 55.1 0.4 1.9e-14 53.6 0.4 1.9 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OWF52640.1 - 0.0093 15.6 0.1 0.061 13.0 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Gelsolin PF00626.22 OWF52641.1 - 2.9e-57 190.5 1.0 3.5e-14 52.4 0.0 6.7 6 0 0 6 6 6 6 Gelsolin repeat LRR_8 PF13855.6 OWF52641.1 - 4.2e-32 109.7 51.5 1.4e-08 34.3 4.4 6.4 4 1 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OWF52641.1 - 9.1e-24 83.2 66.5 2.5e-05 24.6 3.7 9.5 2 1 11 13 13 13 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF52641.1 - 0.054 14.0 49.8 17 6.4 0.2 13.0 13 1 0 13 13 13 0 Leucine Rich Repeat NTF2 PF02136.20 OWF52643.1 - 2.3e-33 115.3 0.1 4.2e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OWF52643.1 - 1.5e-13 50.4 0.1 2.5e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF52643.1 - 6.1e-05 23.1 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif PDEase_I PF00233.19 OWF52644.1 - 6.8e-79 264.9 1.3 6.8e-79 264.9 1.3 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OWF52644.1 - 8.7e-35 120.2 0.0 2.7e-17 63.6 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 OWF52644.1 - 5.9e-13 49.3 0.0 4.2e-06 27.1 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 OWF52644.1 - 2.4e-06 27.9 0.0 0.13 12.6 0.0 3.1 3 0 0 3 3 3 2 GAF domain HD PF01966.22 OWF52644.1 - 0.023 14.9 0.0 0.079 13.2 0.0 2.1 1 0 0 1 1 1 0 HD domain SPARC_Ca_bdg PF10591.9 OWF52645.1 - 1.7e-27 96.0 0.1 3.8e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 OWF52645.1 - 1.3e-06 28.4 12.2 7.2e-06 26.0 9.3 2.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF52645.1 - 0.0048 16.9 10.6 0.018 15.1 7.3 2.8 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.32 OWF52645.1 - 0.037 13.6 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 EF hand MMR_HSR1_C PF08438.10 OWF52646.1 - 6.2e-21 75.1 0.0 1.4e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal RWD PF05773.22 OWF52646.1 - 2.5e-17 63.2 0.1 4.5e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 RWD domain MMR_HSR1 PF01926.23 OWF52646.1 - 1.4e-16 60.6 0.0 3.8e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF52646.1 - 0.00014 21.4 1.1 0.0035 16.9 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OWF52646.1 - 0.033 14.3 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Dynamin family MeaB PF03308.16 OWF52646.1 - 0.082 11.9 0.1 0.42 9.5 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Tropomyosin PF00261.20 OWF52647.1 - 0.0012 18.3 19.6 0.0012 18.3 19.6 2.1 2 0 0 2 2 2 1 Tropomyosin Syntaxin PF00804.25 OWF52647.1 - 0.034 13.8 17.9 0.62 9.7 12.1 2.4 2 0 0 2 2 2 0 Syntaxin Taxilin PF09728.9 OWF52647.1 - 0.1 11.7 25.9 0.27 10.4 19.9 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Cys_rich_FGFR PF00839.17 OWF52647.1 - 0.24 11.6 3.9 29 4.9 0.4 3.5 3 0 0 3 3 3 0 Cysteine rich repeat DUF3584 PF12128.8 OWF52647.1 - 0.33 8.4 24.8 0.33 8.4 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) LacI PF00356.21 OWF52647.1 - 0.39 10.5 1.6 19 5.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Baculo_PEP_C PF04513.12 OWF52647.1 - 0.79 9.8 17.1 0.17 11.9 1.5 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 OWF52647.1 - 0.92 9.0 26.4 0.39 10.3 0.6 2.4 2 1 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 OWF52647.1 - 1.2 9.2 30.9 4.3 7.4 22.3 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OWF52647.1 - 1.2 8.4 28.4 0.87 8.9 20.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) SHE3 PF17078.5 OWF52647.1 - 1.2 8.7 18.5 4.6 6.9 0.2 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 OWF52647.1 - 1.3 9.1 26.1 0.91 9.6 18.7 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.11 OWF52647.1 - 1.3 8.8 12.5 0.84 9.4 5.6 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Leu_zip PF15294.6 OWF52647.1 - 2 7.9 21.2 0.22 11.0 12.5 2.4 2 1 0 2 2 2 0 Leucine zipper Fmp27_WPPW PF10359.9 OWF52647.1 - 2.2 7.0 12.5 0.23 10.3 6.7 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF724 PF05266.14 OWF52647.1 - 2.5 7.9 19.7 1.1 9.1 11.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 OWF52647.1 - 2.6 8.5 21.3 2.1 8.8 14.8 2.2 2 0 0 2 2 2 0 Fez1 MPS2 PF17060.5 OWF52647.1 - 2.8 7.1 16.0 0.67 9.2 11.5 1.9 2 0 0 2 2 2 0 Monopolar spindle protein 2 ING PF12998.7 OWF52647.1 - 3.8 8.1 18.5 3.6 8.2 0.2 3.4 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding HAUS6_N PF14661.6 OWF52647.1 - 4.3 6.8 20.8 10 5.6 0.1 2.7 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF2780 PF11075.8 OWF52647.1 - 6.1 7.0 7.1 1.3 9.2 3.0 1.9 2 1 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) OmpH PF03938.14 OWF52647.1 - 7 7.0 34.1 2.4 8.5 1.0 3.2 2 2 0 2 2 2 0 Outer membrane protein (OmpH-like) SKA1 PF07160.12 OWF52647.1 - 7.3 6.4 21.5 15 5.3 14.8 3.1 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF3450 PF11932.8 OWF52647.1 - 8 5.7 26.5 26 4.0 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 OWF52647.1 - 8 6.6 24.2 2.3 8.4 1.0 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 OWF52647.1 - 8.1 6.4 13.1 5.6 6.9 0.9 3.4 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 OWF52647.1 - 8.8 6.4 30.2 1.7 8.7 10.2 4.0 2 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Tmem26 PF09772.9 OWF52648.1 - 3.9e-26 92.0 2.1 5.5e-26 91.6 2.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 Rhv PF00073.20 OWF52648.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 picornavirus capsid protein Mab-21 PF03281.14 OWF52649.1 - 1.8e-28 99.7 0.8 4.6e-28 98.4 0.1 1.8 2 0 0 2 2 2 1 Mab-21 protein ANAPC3 PF12895.7 OWF52649.1 - 1.3 9.3 4.1 8.5 6.7 0.1 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TMEM173 PF15009.6 OWF52650.1 - 1.4e-57 195.1 0.2 2e-28 99.4 0.1 2.6 2 1 0 2 2 2 2 Transmembrane protein 173 TIR_2 PF13676.6 OWF52650.1 - 4.2e-13 49.9 0.1 2.6e-08 34.5 0.1 3.2 3 0 0 3 3 3 2 TIR domain TIR PF01582.20 OWF52650.1 - 0.00063 19.6 0.2 0.045 13.6 0.0 2.5 2 0 0 2 2 2 1 TIR domain Dynamin_M PF01031.20 OWF52650.1 - 0.027 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Dynamin central region Mab-21 PF03281.14 OWF52651.1 - 1.8e-24 86.6 0.2 2.9e-24 85.9 0.2 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_12 PF13424.6 OWF52651.1 - 0.03 14.6 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Muraidase PF11860.8 OWF52651.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 N-acetylmuramidase HIGH_NTase1 PF05636.11 OWF52653.1 - 0.0064 15.8 1.2 1.9 7.6 0.2 3.1 1 1 2 3 3 3 3 HIGH Nucleotidyl Transferase DUF3860 PF12976.7 OWF52653.1 - 0.0078 16.2 23.5 6.6 6.8 0.7 6.6 1 1 7 8 8 8 8 Domain of Unknown Function with PDB structure (DUF3860) Mucin-like PF16058.5 OWF52654.1 - 0.00063 19.8 0.0 0.00084 19.4 0.0 1.2 1 0 0 1 1 1 1 Mucin-like Fibrinogen_aC PF12160.8 OWF52654.1 - 0.46 10.4 5.1 33 4.4 0.2 3.7 1 1 4 5 5 5 0 Fibrinogen alpha C domain DMA PF03474.14 OWF52654.1 - 1.6 8.4 5.1 1.2e+02 2.4 0.1 5.0 7 0 0 7 7 7 0 DMRTA motif Phenol_monoox PF04663.12 OWF52655.1 - 8.4 6.6 25.3 2.1 8.5 2.1 4.7 1 1 4 5 5 5 0 Phenol hydroxylase conserved region Fucosidase_C PF16757.5 OWF52656.1 - 0.0014 19.1 0.9 13 6.5 0.0 4.3 1 1 3 4 4 4 2 Alpha-L-fucosidase C-terminal domain DUF3581 PF12119.8 OWF52656.1 - 0.21 11.0 0.7 3.3 7.1 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3581) HMG_box PF00505.19 OWF52658.1 - 9.9e-26 90.0 1.5 1.6e-25 89.3 1.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.8 OWF52658.1 - 4.7e-15 56.5 0.0 4.7e-15 56.5 0.0 3.3 3 1 1 4 4 4 1 Sox developmental protein N terminal HMG_box_2 PF09011.10 OWF52658.1 - 3.1e-10 40.5 1.1 5.6e-10 39.7 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain AAA_21 PF13304.6 OWF52659.1 - 0.028 14.3 0.1 0.034 14.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1681 PF07933.14 OWF52659.1 - 0.092 12.4 6.0 46 3.7 0.1 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1681) IMCp PF12314.8 OWF52659.1 - 0.14 12.5 0.1 7.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Inner membrane complex protein TDRP PF15683.5 OWF52659.1 - 3.5 7.6 20.9 8.1 6.4 1.2 5.4 1 1 4 5 5 5 0 Testis development-related protein Pentapeptide_4 PF13599.6 OWF52662.1 - 0.013 15.6 0.0 1.8 8.7 0.0 3.6 1 1 2 4 4 4 0 Pentapeptide repeats (9 copies) DUF846 PF05832.12 OWF52663.1 - 2e-53 180.2 16.7 2.3e-53 180.0 16.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5480 PF17576.2 OWF52663.1 - 5.4 7.1 5.7 47 4.0 0.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5480) Halogen_Hydrol PF10112.9 OWF52663.1 - 7.4 6.5 5.9 3 7.8 0.7 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PPR_2 PF13041.6 OWF52664.1 - 1e-24 86.4 2.7 4.8e-09 36.3 0.0 6.3 5 2 2 7 7 7 4 PPR repeat family PPR_3 PF13812.6 OWF52664.1 - 9.4e-23 80.1 4.5 1.4e-06 28.3 0.0 6.7 5 1 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.4 OWF52664.1 - 4.6e-15 55.6 0.1 6.3e-09 35.5 0.0 3.3 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OWF52664.1 - 2e-09 37.0 6.8 0.0018 18.0 0.0 7.0 6 1 0 6 6 6 1 PPR repeat PPR PF01535.20 OWF52664.1 - 1.4e-07 31.2 4.2 0.32 11.3 0.0 5.8 5 0 0 5 5 5 2 PPR repeat ECSIT PF06239.11 OWF52664.1 - 8.9e-06 25.0 0.1 0.024 13.8 0.0 3.8 3 1 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway DUF2315 PF10231.9 OWF52664.1 - 0.38 10.9 6.0 0.054 13.6 1.2 2.0 2 0 0 2 2 2 0 Apoptogenic protein 1 CbiG_mid PF11761.8 OWF52664.1 - 5.4 7.2 8.1 2.6e+03 -1.4 8.1 4.0 1 1 0 1 1 1 0 Cobalamin biosynthesis central region DUF4064 PF13273.6 OWF52665.1 - 0.034 14.4 0.4 0.5 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Phage_holin_3_6 PF07332.11 OWF52665.1 - 0.099 12.7 3.8 0.18 11.8 3.8 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4199 PF13858.6 OWF52665.1 - 0.1 13.0 0.8 0.18 12.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PIRT PF15099.6 OWF52665.1 - 0.11 12.1 0.7 0.21 11.2 0.7 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family WD40 PF00400.32 OWF52666.1 - 1.4e-37 127.0 58.4 0.017 15.9 0.1 20.2 21 1 0 21 21 21 12 WD domain, G-beta repeat DUF667 PF05018.13 OWF52666.1 - 2.7e-33 115.3 0.1 1.4e-24 86.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF667) ANAPC4_WD40 PF12894.7 OWF52666.1 - 1.2e-19 70.4 1.7 0.0014 18.9 0.0 11.3 8 5 5 13 13 13 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF52666.1 - 8.1e-10 38.9 0.6 1.8 8.4 0.0 6.7 6 1 1 7 7 7 3 Eukaryotic translation initiation factor eIF2A HELP PF03451.14 OWF52666.1 - 2.5e-08 33.6 0.0 0.00013 21.7 0.0 2.7 2 0 0 2 2 2 2 HELP motif WD40_like PF17005.5 OWF52666.1 - 2e-05 24.1 0.5 4 6.7 0.0 5.4 6 0 0 6 6 6 2 WD40-like domain Nup160 PF11715.8 OWF52666.1 - 0.00036 19.3 3.1 2.8 6.5 0.0 4.4 4 1 0 4 4 4 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OWF52666.1 - 0.0005 20.5 0.4 0.64 10.6 0.1 5.6 6 0 0 6 6 6 1 PQQ-like domain Nucleoporin_N PF08801.11 OWF52666.1 - 0.05 12.4 0.4 6.4 5.4 0.0 4.2 4 1 1 5 5 5 0 Nup133 N terminal like PD40 PF07676.12 OWF52666.1 - 0.053 13.5 1.9 26 4.9 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PRELI PF04707.14 OWF52667.1 - 8.2e-50 168.7 0.5 1.2e-49 168.1 0.5 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 OWF52667.1 - 5.7e-41 139.9 0.0 9e-41 139.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OWF52667.1 - 1.9e-05 24.7 0.2 4e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain MitMem_reg PF13012.6 OWF52667.1 - 0.14 12.6 0.0 0.5 10.8 0.0 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function zf-3CxxC_2 PF17180.4 OWF52668.1 - 1.2e-26 93.3 9.5 1.2e-26 93.3 9.5 1.7 2 0 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 OWF52668.1 - 2.1e-11 43.4 2.9 2.1e-11 43.4 2.9 3.0 4 0 0 4 4 4 1 Zinc knuckle UPF0515 PF15135.6 OWF52668.1 - 0.00072 19.0 7.2 0.0013 18.1 7.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 OWF52668.1 - 0.003 18.0 14.3 0.15 12.6 14.1 2.9 2 1 0 2 2 2 1 Zinc-binding domain zf-CHY PF05495.12 OWF52668.1 - 0.13 12.8 10.9 2.2 8.8 2.5 2.3 2 0 0 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 OWF52668.1 - 4.5 7.8 9.7 0.71 10.4 5.6 1.7 2 0 0 2 2 2 0 Cytochrome c3 Vitellogenin_N PF01347.22 OWF52669.1 - 1.4e-38 132.8 0.1 2e-38 132.2 0.1 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region HEAT_2 PF13646.6 OWF52669.1 - 0.017 15.5 0.0 5.9 7.4 0.0 3.4 1 1 2 3 3 3 0 HEAT repeats tRNA_m1G_MT PF01746.21 OWF52670.1 - 3.5e-32 111.7 0.1 3.5e-32 111.7 0.1 2.3 3 1 0 3 3 3 1 tRNA (Guanine-1)-methyltransferase ARA70 PF12489.8 OWF52670.1 - 1.7 8.9 8.8 0.38 10.9 0.7 2.3 2 0 0 2 2 2 0 Nuclear coactivator DEAD PF00270.29 OWF52672.1 - 9.4e-47 159.0 0.0 1.9e-46 158.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF52672.1 - 2.9e-31 108.1 0.0 1.6e-30 105.7 0.0 2.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF52672.1 - 0.0012 18.9 0.0 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OWF52672.1 - 0.0021 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UvrD_C PF13361.6 OWF52672.1 - 0.11 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ferritin PF00210.24 OWF52672.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Ferritin-like domain CMS1 PF14617.6 OWF52672.1 - 0.16 11.3 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit RNase_PH PF01138.21 OWF52673.1 - 9.2e-19 68.3 0.0 1.7e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OWF52673.1 - 1.2e-05 25.2 0.6 3.5e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 sCache_3_3 PF17202.4 OWF52673.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 RhoGAP PF00620.27 OWF52674.1 - 8.2e-42 142.6 0.0 1.9e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 OWF52674.1 - 1.8e-36 126.0 8.1 2.4e-36 125.6 8.1 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 OWF52674.1 - 0.016 14.4 5.2 0.028 13.6 5.2 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking RRS1 PF04939.12 OWF52675.1 - 2.1e-23 83.0 8.3 2.1e-23 83.0 8.3 3.0 1 1 1 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) DUF4573 PF15140.6 OWF52676.1 - 1e-06 28.7 4.5 0.016 15.1 0.4 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) DUF4573 PF15140.6 OWF52677.1 - 8e-12 45.3 9.3 4.5e-11 42.9 9.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) Laminin_EGF PF00053.24 OWF52677.1 - 1 9.6 8.4 5.3 7.3 0.6 2.6 2 0 0 2 2 2 0 Laminin EGF domain DUF3664 PF12406.8 OWF52677.1 - 1.8 9.2 6.7 9.7 6.9 1.5 2.4 1 1 1 2 2 2 0 Surface protein DUF3060 PF11259.8 OWF52678.1 - 2.1e-18 65.7 25.8 0.00084 19.0 0.8 6.8 2 2 3 6 6 6 6 Protein of unknown function (DUF3060) PY_rept_46 PF09689.10 OWF52678.1 - 2.2e-07 31.3 1.3 26 5.5 0.0 7.7 1 1 11 12 12 12 1 Plasmodium yoelii repeat (PY_rept_46) Tcp10_C PF07202.13 OWF52678.1 - 0.011 15.7 3.7 1.9 8.4 0.2 3.2 1 1 2 4 4 4 0 T-complex protein 10 C-terminus PTCRA PF15028.6 OWF52678.1 - 0.43 10.3 10.9 19 4.9 0.0 7.3 2 2 5 9 9 9 0 Pre-T-cell antigen receptor DUF3060 PF11259.8 OWF52679.1 - 5.6e-07 29.2 12.0 0.085 12.6 0.0 4.5 2 1 0 4 4 4 3 Protein of unknown function (DUF3060) PY_rept_46 PF09689.10 OWF52679.1 - 0.0006 20.3 0.5 81 3.9 0.0 5.2 3 1 3 6 6 6 0 Plasmodium yoelii repeat (PY_rept_46) Tcp10_C PF07202.13 OWF52679.1 - 0.041 13.8 0.5 0.41 10.6 0.3 2.3 1 1 2 3 3 3 0 T-complex protein 10 C-terminus RL11D PF11088.8 OWF52679.1 - 0.067 13.5 1.1 8.1 6.8 0.0 3.0 1 1 2 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 Yop-YscD_cpl PF16697.5 OWF52679.1 - 0.57 10.5 11.8 21 5.5 0.2 4.4 1 1 3 4 4 4 0 Inner membrane component of T3SS, cytoplasmic domain RabGGT_insert PF07711.11 OWF52679.1 - 1.4 9.5 4.2 13 6.3 0.1 3.1 1 1 3 4 4 4 0 Rab geranylgeranyl transferase alpha-subunit, insert domain Gp5_C PF06715.12 OWF52679.1 - 2.3 8.5 11.3 18 5.8 0.0 6.1 5 1 2 7 7 7 0 Gp5 C-terminal repeat (3 copies) UPF0158 PF03682.13 OWF52680.1 - 0.044 13.8 0.8 0.18 11.7 0.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0158) Leu_Phe_trans PF03588.14 OWF52680.1 - 1.4 8.4 7.4 2 7.9 0.3 3.3 2 1 0 3 3 3 0 Leucyl/phenylalanyl-tRNA protein transferase Apolipoprotein PF01442.18 OWF52681.1 - 7.2e-06 26.0 0.0 0.12 12.2 0.0 2.0 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Collagen_mid PF15984.5 OWF52681.1 - 0.0011 18.8 29.1 0.13 12.0 23.9 2.7 1 1 1 2 2 2 2 Bacterial collagen, middle region BORCS6 PF10157.9 OWF52681.1 - 0.0026 18.0 14.6 0.068 13.4 2.9 2.9 1 1 2 3 3 3 2 BLOC-1-related complex sub-unit 6 Baculo_PEP_C PF04513.12 OWF52681.1 - 0.0044 17.1 2.7 0.3 11.1 0.3 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Chlorosome_CsmC PF11098.8 OWF52681.1 - 0.0055 16.7 34.1 0.039 13.9 16.4 3.3 1 1 1 2 2 2 2 Chlorosome envelope protein C Phasin PF05597.11 OWF52681.1 - 0.006 16.6 5.5 0.26 11.3 0.3 2.8 1 1 1 2 2 2 2 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2884 PF11101.8 OWF52681.1 - 0.023 14.2 3.2 0.072 12.6 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Rep_4 PF05797.11 OWF52681.1 - 0.088 11.9 2.3 0.61 9.2 0.4 2.0 1 1 1 2 2 2 0 Yeast trans-acting factor (REP1/REP2) MalM PF07148.12 OWF52682.1 - 0.064 13.0 0.1 0.53 10.1 0.1 2.2 1 1 1 2 2 2 0 Maltose operon periplasmic protein precursor (MalM) Zfx_Zfy_act PF04704.13 OWF52682.1 - 0.21 10.7 1.0 0.61 9.1 0.4 1.7 1 1 1 2 2 2 0 Zfx / Zfy transcription activation region Hep_core_N PF08290.11 OWF52682.1 - 2 8.5 15.5 17 5.5 1.1 5.3 4 1 1 5 5 5 0 Hepatitis core protein, putative zinc finger Collagen_mid PF15984.5 OWF52683.1 - 2.6e-05 24.1 33.6 0.007 16.1 12.2 2.3 1 1 1 2 2 2 2 Bacterial collagen, middle region Apolipoprotein PF01442.18 OWF52683.1 - 0.00017 21.5 0.0 0.0016 18.3 0.0 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lipid_bd PF12888.7 OWF52683.1 - 0.0038 17.6 13.1 0.85 10.1 0.4 3.6 1 1 3 4 4 4 3 Lipid-binding putative hydrolase BORCS6 PF10157.9 OWF52683.1 - 0.013 15.7 18.5 0.36 11.0 3.5 2.5 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 6 HTH_15 PF12324.8 OWF52683.1 - 0.023 14.7 8.8 6.5 6.8 0.6 5.7 1 1 4 6 6 6 0 Helix-turn-helix domain of alkylmercury lyase CLASP_N PF12348.8 OWF52683.1 - 0.035 13.7 0.0 3.3 7.2 0.0 2.8 1 1 3 4 4 4 0 CLASP N terminal DUF4197 PF13852.6 OWF52683.1 - 0.039 13.6 0.9 1.5 8.5 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4197) Prominin PF05478.11 OWF52683.1 - 0.056 11.4 0.5 0.07 11.1 0.5 1.2 1 0 0 1 1 1 0 Prominin NMT1 PF09084.11 OWF52683.1 - 0.17 11.8 6.8 0.24 11.3 5.9 1.8 1 1 1 2 2 2 0 NMT1/THI5 like Tape_meas_lam_C PF09718.10 OWF52683.1 - 0.53 10.5 11.3 0.36 11.0 0.4 3.5 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Gene66 PF02053.15 OWF52683.1 - 0.8 9.3 2.7 1.1 8.8 1.8 1.8 1 1 0 1 1 1 0 Gene 66 (IR5) protein Coiled PF05710.12 OWF52683.1 - 3.9 8.4 27.9 8.1 7.3 7.7 4.1 1 1 2 3 3 3 0 Coiled coil Axin_b-cat_bind PF08833.10 OWF52684.1 - 0.0018 18.4 12.6 0.54 10.4 2.1 3.6 1 1 1 2 2 2 2 Axin beta-catenin binding domain CTD PF12815.7 OWF52684.1 - 0.025 15.1 11.7 0.04 14.5 11.7 1.4 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3504 PF12012.8 OWF52684.1 - 0.06 13.3 11.3 0.31 10.9 3.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3504) DUF1820 PF08850.11 OWF52684.1 - 0.15 12.6 0.7 0.55 10.8 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1820) Abhydrolase_1 PF00561.20 OWF52686.1 - 1.9e-25 90.0 0.1 2.9e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OWF52686.1 - 2.8e-23 81.3 0.1 1.1e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 OWF52686.1 - 8.8e-09 35.0 0.0 7e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 I-set PF07679.16 OWF52687.1 - 0.0014 18.7 0.2 1 9.5 0.0 3.3 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF52687.1 - 0.002 18.7 0.2 0.043 14.4 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 OWF52687.1 - 0.0026 18.1 2.3 0.016 15.5 0.2 3.1 3 1 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 OWF52687.1 - 0.0029 17.8 0.0 0.027 14.7 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin V-set domain Invasin_D3 PF09134.10 OWF52687.1 - 0.089 13.1 0.0 0.27 11.6 0.0 1.8 1 1 0 1 1 1 0 Invasin, domain 3 PGM_PMM_II PF02879.16 OWF52688.1 - 0.0037 17.9 9.6 4.3 8.0 1.2 4.2 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Grg1 PF11034.8 OWF52688.1 - 0.0097 16.1 64.2 1.1 9.5 3.7 7.2 1 1 4 5 5 4 2 Glucose-repressible protein Grg1 MgtE_N PF03448.17 OWF52688.1 - 0.024 15.2 6.2 0.59 10.8 1.4 3.0 1 1 1 3 3 3 0 MgtE intracellular N domain ATC_hydrolase PF14196.6 OWF52688.1 - 0.055 14.3 35.1 2.9 8.7 6.1 4.8 1 1 3 4 4 4 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase ADSL_C PF10397.9 OWF52688.1 - 0.095 13.3 23.3 4.8e+02 1.4 2.1 6.3 1 1 1 2 2 1 0 Adenylosuccinate lyase C-terminus BLM10_mid PF16507.5 OWF52688.1 - 0.15 10.7 7.0 0.22 10.1 0.2 2.4 1 1 1 2 2 2 0 Proteasome-substrate-size regulator, mid region DUF4371 PF14291.6 OWF52688.1 - 0.22 11.1 10.3 3.8 7.1 0.6 3.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4371) HNOB PF07700.15 OWF52688.1 - 0.71 9.8 8.5 2.1 8.3 1.0 3.2 1 1 1 3 3 3 0 Haem-NO-binding Pro_dh-DNA_bdg PF14850.6 OWF52688.1 - 0.79 10.3 19.8 24 5.5 1.9 5.9 2 1 4 6 6 6 0 DNA-binding domain of Proline dehydrogenase CelTOS PF18659.1 OWF52688.1 - 0.86 10.1 26.9 5 7.6 4.4 4.2 1 1 2 3 3 2 0 Cell-traversal protein for ookinetes and sporozoites WPP PF13943.6 OWF52688.1 - 4 7.9 30.8 1.5 9.2 5.9 3.6 1 1 3 4 4 4 0 WPP domain MIEAP PF16026.5 OWF52688.1 - 4.1 7.6 9.7 7.2e+02 0.2 9.7 2.9 1 1 0 1 1 1 0 Mitochondria-eating protein SseC PF04888.12 OWF52688.1 - 5.1 6.6 59.6 1.8e+04 -18.8 59.6 4.0 1 1 0 1 1 0 0 Secretion system effector C (SseC) like family TTL PF03133.15 OWF52688.1 - 5.8 5.9 9.7 74 2.3 0.2 3.2 1 1 1 2 2 2 0 Tubulin-tyrosine ligase family Hypoth_Ymh PF09509.10 OWF52688.1 - 7.1 6.6 17.0 7.5 6.5 1.6 3.6 1 1 2 3 3 3 0 Protein of unknown function (Hypoth_ymh) SRI PF08236.11 OWF52688.1 - 8.9 6.6 30.2 8.5 6.6 3.7 4.7 1 1 1 2 2 1 0 SRI (Set2 Rpb1 interacting) domain SRCR PF00530.18 OWF52689.1 - 1e-20 74.0 0.1 1.3e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF52689.1 - 0.015 15.8 0.4 0.03 14.9 0.4 1.6 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain DUF3114 PF11311.8 OWF52689.1 - 0.066 12.7 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) SRCR PF00530.18 OWF52690.1 - 1.9e-08 34.7 0.0 1.9e-08 34.7 0.0 2.7 2 1 0 2 2 2 1 Scavenger receptor cysteine-rich domain MAM PF00629.23 OWF52691.1 - 2.1e-129 427.6 0.0 3.1e-29 102.0 0.0 5.4 5 0 0 5 5 5 5 MAM domain, meprin/A5/mu EGF PF00008.27 OWF52691.1 - 5.8e-22 77.6 51.9 6.8e-07 29.5 2.7 4.8 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 OWF52691.1 - 1.3e-12 47.9 43.0 5.4e-05 23.7 1.6 5.6 4 0 0 4 4 4 4 Human growth factor-like EGF EGF_2 PF07974.13 OWF52691.1 - 0.01 16.2 55.3 0.18 12.2 13.3 4.7 4 0 0 4 4 4 0 EGF-like domain RhoGEF PF00621.20 OWF52693.1 - 2.2e-40 138.8 0.4 2.2e-40 138.8 0.4 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 OWF52693.1 - 1.4e-05 25.6 0.0 8.3e-05 23.0 0.0 2.5 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 OWF52693.1 - 0.00071 19.8 0.5 0.17 12.1 0.1 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain HOOK PF05622.12 OWF52694.1 - 3.5e-31 108.1 75.4 3.5e-31 108.1 75.4 7.1 1 1 4 5 5 5 1 HOOK protein KASH_CCD PF14662.6 OWF52694.1 - 4.5e-06 26.6 44.2 2.6e-05 24.1 25.3 12.9 1 1 12 13 13 13 6 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 OWF52694.1 - 0.0021 18.3 25.3 0.0021 18.3 25.3 13.0 3 1 10 13 13 13 2 Autophagy protein 16 (ATG16) TSC22 PF01166.18 OWF52694.1 - 0.031 14.6 0.4 0.031 14.6 0.4 18.5 9 4 8 19 19 19 0 TSC-22/dip/bun family HALZ PF02183.18 OWF52694.1 - 0.084 13.1 0.1 0.042 14.1 0.4 22.6 19 6 6 25 25 25 0 Homeobox associated leucine zipper SprT-like PF10263.9 OWF52695.1 - 2.5e-27 95.0 0.0 7e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 OWF52695.1 - 0.032 14.5 0.7 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 Effector protein zf_UBZ PF18439.1 OWF52695.1 - 0.15 11.7 0.4 0.32 10.6 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 OWF52695.1 - 0.82 9.5 6.8 0.095 12.6 0.7 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Pkinase PF00069.25 OWF52696.1 - 3.8e-35 121.5 0.0 8.3e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF52696.1 - 1.2e-21 77.2 0.0 2.1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF52696.1 - 0.087 12.7 0.0 9.8 6.0 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family TMEM174 PF15029.6 OWF52696.1 - 6.7 6.4 6.1 12 5.5 2.2 2.6 2 0 0 2 2 2 0 Transmembrane protein 174 B56 PF01603.20 OWF52697.1 - 2.5e-193 642.7 9.9 3.1e-193 642.4 9.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 OWF52697.1 - 0.12 12.3 4.4 0.56 10.1 0.2 2.9 3 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal MAS20 PF02064.15 OWF52698.1 - 8.2e-42 142.4 0.6 1.7e-41 141.4 0.6 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor bZIP_Maf PF03131.17 OWF52699.1 - 3.3e-18 66.0 3.8 3.3e-18 66.0 3.8 2.6 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 OWF52699.1 - 9.1e-08 32.1 4.4 3.4e-07 30.3 4.4 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF52699.1 - 0.0072 16.4 3.0 0.0072 16.4 3.0 2.9 2 0 0 2 2 2 1 Basic region leucine zipper Ras PF00071.22 OWF52700.1 - 4e-44 150.1 0.1 4.8e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF52700.1 - 8.2e-17 61.5 0.1 1.1e-16 61.2 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF52700.1 - 7e-12 45.1 0.0 8.6e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF52700.1 - 1.4e-05 24.8 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF52700.1 - 8.3e-05 22.6 0.1 0.00011 22.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF52700.1 - 0.0059 16.5 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OWF52700.1 - 0.0092 15.4 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 OWF52700.1 - 0.058 13.4 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-RING_UBOX PF13445.6 OWF52701.1 - 1.8e-09 37.5 6.3 6e-09 35.8 6.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF52701.1 - 7.9e-08 32.0 4.4 2.8e-07 30.3 4.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF52701.1 - 1.5e-07 31.2 2.6 5.9e-07 29.3 2.6 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF52701.1 - 7e-07 29.3 3.6 7e-07 29.3 3.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF52701.1 - 8.3e-06 26.0 4.0 8.3e-06 26.0 4.0 2.4 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF52701.1 - 5.7e-05 22.9 1.2 5.7e-05 22.9 1.2 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF52701.1 - 6.8e-05 22.7 2.5 6.8e-05 22.7 2.5 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.6 OWF52701.1 - 0.00018 21.3 1.6 0.00053 19.8 1.6 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 OWF52701.1 - 0.0014 18.4 1.4 0.004 16.9 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Erp_C PF06780.11 OWF52701.1 - 0.0081 16.2 0.4 0.019 15.0 0.3 1.6 1 1 0 1 1 1 1 Erp protein C-terminus PQQ_2 PF13360.6 OWF52701.1 - 0.015 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain Prok-RING_4 PF14447.6 OWF52701.1 - 0.044 13.6 3.3 0.58 10.1 3.9 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF52701.1 - 0.17 11.6 3.2 0.45 10.3 3.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger MIB_HERC2 PF06701.13 OWF52702.1 - 5.3e-23 81.0 12.6 7.2e-15 55.0 0.7 2.8 2 0 0 2 2 2 2 Mib_herc2 VWA_2 PF13519.6 OWF52702.1 - 2.3e-09 37.8 0.0 6.9e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF52702.1 - 2.2e-06 28.0 0.0 5.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4685 PF15737.5 OWF52702.1 - 0.057 13.9 3.4 0.15 12.5 3.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) IMS PF00817.20 OWF52703.1 - 1.3e-43 148.5 0.0 4.3e-43 146.9 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 OWF52703.1 - 1e-17 64.9 0.5 2.3e-17 63.7 0.5 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-C2H2_12 PF18658.1 OWF52703.1 - 0.017 14.7 1.8 2.7 7.6 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger C2H2-type IMS_HHH PF11798.8 OWF52703.1 - 0.066 13.6 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 IMS family HHH motif Zn-C2H2_12 PF18112.1 OWF52703.1 - 6.9 7.2 13.3 0.57 10.7 0.6 3.9 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain ADAM_spacer1 PF05986.14 OWF52704.1 - 4.2e-31 107.3 0.1 7.7e-31 106.5 0.1 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 OWF52704.1 - 3.8e-30 105.0 0.2 8.2e-30 103.9 0.2 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.19 OWF52704.1 - 9.7e-24 83.3 117.0 1.3e-07 31.7 7.8 10.5 10 0 0 10 10 10 7 Thrombospondin type 1 domain Reprolysin PF01421.19 OWF52704.1 - 1e-23 84.3 0.2 1.7e-23 83.6 0.2 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 OWF52704.1 - 1e-20 74.0 8.7 1e-20 74.0 8.7 6.8 6 3 1 7 7 2 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF52704.1 - 3.1e-12 47.0 0.1 1e-11 45.4 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF52704.1 - 1.2e-09 38.8 0.0 3.3e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF52704.1 - 3.8e-07 30.2 0.1 9.3e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF52704.1 - 8.3e-06 25.6 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF52704.1 - 0.072 12.9 0.2 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 Matrixin Zincin_1 PF06262.11 OWF52704.1 - 0.075 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase RhoGEF PF00621.20 OWF52705.1 - 1.2e-29 103.9 4.0 1.2e-29 103.9 4.0 2.6 2 1 0 2 2 2 1 RhoGEF domain PH_16 PF17838.1 OWF52705.1 - 1.6e-26 92.6 0.0 3.4e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Baculo_PEP_C PF04513.12 OWF52705.1 - 0.053 13.6 3.6 0.29 11.2 0.4 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YodL PF14191.6 OWF52705.1 - 3.2 8.7 7.3 1.2 10.1 0.0 3.6 3 1 1 4 4 4 0 YodL-like C1_1 PF00130.22 OWF52706.1 - 7e-07 29.0 7.3 1.2e-06 28.3 7.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 OWF52706.1 - 1.5 8.8 7.3 3.3 7.7 7.3 1.6 1 0 0 1 1 1 0 PHD-finger Spo0M PF07070.11 OWF52707.1 - 3.5e-05 23.4 0.1 0.054 13.0 0.1 2.7 2 1 0 2 2 2 2 SpoOM protein DUF2715 PF10895.8 OWF52707.1 - 0.00014 21.5 0.8 0.047 13.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2715) MspA PF09203.11 OWF52707.1 - 0.062 13.2 9.7 0.15 11.9 1.2 2.2 2 0 0 2 2 2 0 MspA MatE PF01554.18 OWF52707.1 - 0.17 11.5 3.0 26 4.4 0.6 3.0 2 1 1 3 3 3 0 MatE LRR_1 PF00560.33 OWF52707.1 - 0.69 10.7 22.3 2.2e+02 3.1 0.1 9.0 8 2 0 8 8 8 0 Leucine Rich Repeat Chlam_vir PF05475.11 OWF52707.1 - 1.1 9.0 3.6 10 5.8 0.7 2.1 2 0 0 2 2 2 0 Pgp3 C-terminal domain ThiF PF00899.21 OWF52708.1 - 1.6e-96 322.4 0.0 5.9e-65 219.0 0.0 2.1 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OWF52708.1 - 3.1e-74 250.1 1.5 5.2e-74 249.3 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OWF52708.1 - 5.8e-27 93.7 0.1 1.5e-26 92.4 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 OWF52708.1 - 4.7e-21 74.8 0.6 1.1e-20 73.6 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 OWF52708.1 - 6.5e-16 58.8 0.0 4.9e-14 52.8 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin fold domain 2-Hacid_dh_C PF02826.19 OWF52708.1 - 0.062 12.7 0.3 2.1 7.6 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_4 PF13637.6 OWF52710.1 - 3.6e-23 81.6 0.7 4e-15 56.0 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF52710.1 - 1.3e-22 79.5 0.8 4e-09 36.5 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF52710.1 - 1.1e-17 64.4 0.1 2.1e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF52710.1 - 8.3e-17 60.8 0.1 1.7e-06 28.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat SH3_1 PF00018.28 OWF52710.1 - 5.9e-12 45.0 0.0 1.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.6 OWF52710.1 - 4.5e-11 42.0 0.0 0.00064 20.0 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat SH3_9 PF14604.6 OWF52710.1 - 1.1e-08 34.8 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF52710.1 - 1e-07 31.5 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PX PF00787.24 OWF52711.1 - 2.3e-18 66.2 0.1 5.8e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 PX domain RA PF00788.23 OWF52711.1 - 4.4e-10 40.1 0.2 8.6e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SNX17_FERM_C PF18116.1 OWF52711.1 - 0.00019 21.5 1.0 0.00048 20.2 0.0 2.1 2 0 0 2 2 2 1 Sorting Nexin 17 FERM C-terminal domain PDZ_6 PF17820.1 OWF52711.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain 7tm_1 PF00001.21 OWF52712.1 - 1e-52 179.1 27.7 1.3e-52 178.8 27.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF52712.1 - 1.3e-06 28.3 34.4 1.8e-06 27.8 31.2 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF52712.1 - 5.1e-06 26.1 30.0 7.6e-06 25.5 30.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 OWF52712.1 - 0.0034 16.7 26.5 0.018 14.3 26.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 OWF52712.1 - 0.026 14.3 25.1 0.11 12.2 25.1 2.0 1 1 0 1 1 1 0 Olfactory receptor DUF2116 PF09889.9 OWF52712.1 - 5.9 6.9 8.5 16 5.6 0.4 3.2 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YmgB PF10798.8 OWF52713.1 - 0.28 11.0 5.1 9.4 6.1 0.3 3.0 2 1 1 3 3 3 0 Biofilm development protein YmgB/AriR DUF4116 PF13475.6 OWF52713.1 - 0.28 10.9 1.3 35 4.2 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4116) Nas2_N PF18265.1 OWF52713.1 - 0.42 10.6 5.5 12 5.9 0.8 3.4 1 1 0 3 3 3 0 Nas2 N_terminal domain DUF1154 PF06631.11 OWF52713.1 - 0.92 9.6 2.6 33 4.6 0.0 4.1 3 2 2 6 6 6 0 Protein of unknown function (DUF1154) Cobalamin_bind PF01122.19 OWF52714.1 - 2.3e-19 69.5 0.2 1.6e-18 66.7 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.6 OWF52714.1 - 3.8e-09 37.0 0.0 9.1e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4430) DIOX_N PF14226.6 OWF52715.1 - 3.9e-14 53.4 0.2 5.9e-14 52.8 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OWF52715.1 - 1.5e-13 51.1 0.0 3.6e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cobalamin_bind PF01122.19 OWF52716.1 - 3e-17 62.5 1.2 7.7e-17 61.2 1.2 1.6 1 1 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.6 OWF52716.1 - 2.2e-09 37.8 0.0 4.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Cobalamin_bind PF01122.19 OWF52718.1 - 0.0021 17.0 1.1 0.0067 15.4 1.1 1.7 1 1 0 1 1 1 1 Eukaryotic cobalamin-binding protein Aminotran_3 PF00202.21 OWF52719.1 - 5.1e-82 275.7 0.0 6.2e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.25 OWF52720.1 - 6.6e-46 156.2 0.1 8e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF52720.1 - 1.5e-35 122.9 0.1 1.7e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF52720.1 - 1.5e-14 54.3 0.3 2.3e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OWF52720.1 - 2.3e-07 30.9 0.0 2.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OWF52720.1 - 1.6e-05 24.5 0.3 0.00011 21.7 0.1 2.2 2 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF52720.1 - 0.00091 18.7 0.0 0.0054 16.2 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 OWF52720.1 - 0.0011 19.5 0.8 0.0019 18.8 0.2 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 OWF52720.1 - 0.042 12.9 0.1 0.064 12.4 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4795 PF16043.5 OWF52721.1 - 5.4e-60 202.5 13.0 5.3e-59 199.3 2.5 5.2 5 1 1 6 6 6 3 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 OWF52721.1 - 0.00046 20.2 25.3 0.085 12.9 0.4 5.9 5 1 0 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4279 PF14106.6 OWF52721.1 - 0.0043 17.2 5.0 1.2 9.3 0.2 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4279) DUF948 PF06103.11 OWF52721.1 - 0.011 16.0 22.8 1.3 9.3 0.0 6.1 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) HSBP1 PF06825.12 OWF52721.1 - 0.062 13.2 17.9 0.15 12.0 2.0 5.3 3 1 1 4 4 4 0 Heat shock factor binding protein 1 Peptidase_S41_N PF11918.8 OWF52721.1 - 0.063 13.5 10.1 0.19 12.0 2.2 3.2 3 0 0 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP OrsD PF12013.8 OWF52721.1 - 0.22 12.0 1.4 12 6.4 0.0 3.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D EspB_PE PF18625.1 OWF52721.1 - 0.49 10.9 4.2 0.4 11.2 0.1 3.0 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain FUSC PF04632.12 OWF52721.1 - 0.5 8.8 3.6 4.8 5.6 0.4 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family HsbA PF12296.8 OWF52721.1 - 0.95 9.9 9.3 1.6 9.2 0.6 4.5 4 1 0 4 4 4 0 Hydrophobic surface binding protein A MtrB PF05440.12 OWF52721.1 - 1.9 9.0 5.9 2.6 8.5 0.3 3.7 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Spc7 PF08317.11 OWF52721.1 - 5.7 5.7 44.9 0.14 11.1 10.1 5.2 4 2 1 5 5 5 0 Spc7 kinetochore protein DUF1664 PF07889.12 OWF52721.1 - 6 6.9 31.0 1.7 8.7 0.9 6.8 6 1 2 8 8 8 0 Protein of unknown function (DUF1664) CdvA PF18822.1 OWF52721.1 - 7.4 6.4 35.9 0.93 9.3 0.3 7.2 7 0 0 7 7 7 0 CdvA-like coiled-coil domain WD40 PF00400.32 OWF52722.1 - 2e-16 60.1 9.3 0.011 16.6 0.0 8.3 9 0 0 9 9 9 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OWF52722.1 - 8.9e-07 28.0 3.4 0.0055 15.5 0.0 4.1 4 0 0 4 4 4 3 Nup133 N terminal like EF-hand_7 PF13499.6 OWF52722.1 - 2.5e-06 27.8 0.1 1e-05 25.9 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain pair ANAPC4_WD40 PF12894.7 OWF52722.1 - 3.3e-06 27.3 0.7 0.068 13.5 0.2 5.7 5 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 OWF52722.1 - 1e-05 25.2 0.4 3.2e-05 23.7 0.4 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OWF52722.1 - 0.00014 21.2 0.0 0.00058 19.2 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OWF52722.1 - 0.0021 17.9 0.0 0.01 15.7 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain Cbl_N2 PF02761.14 OWF52722.1 - 0.035 14.8 0.0 0.12 13.1 0.0 2.0 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain EF-hand_5 PF13202.6 OWF52722.1 - 0.041 13.4 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 EF hand TMEM220 PF15071.6 OWF52723.1 - 7.5e-21 74.8 1.3 7.5e-21 74.8 1.3 1.9 2 0 0 2 2 2 1 Transmembrane family 220, helix PRIMA1 PF16101.5 OWF52723.1 - 0.043 13.8 0.3 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UCH PF00443.29 OWF52724.1 - 1.7e-54 185.1 0.4 2.1e-54 184.7 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF52724.1 - 2.7e-21 76.5 6.8 1.6e-20 73.9 6.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OWF52724.1 - 2.7e-13 50.0 11.6 2.7e-13 50.0 11.6 3.1 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 OWF52724.1 - 0.25 10.8 0.1 0.25 10.8 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase adh_short PF00106.25 OWF52725.1 - 6.5e-36 123.6 0.3 8.2e-36 123.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF52725.1 - 2.3e-27 96.1 0.1 2.9e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF52725.1 - 0.00015 21.8 0.1 0.00021 21.3 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF52725.1 - 0.0021 17.5 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Mito_morph_reg PF14972.6 OWF52726.1 - 7.5e-54 181.7 0.0 8.6e-54 181.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator Viral_env_E26 PF11050.8 OWF52726.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 LRR_6 PF13516.6 OWF52727.1 - 3.2e-17 61.1 8.6 0.0028 17.6 0.0 8.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 OWF52727.1 - 2.6e-14 53.1 6.9 0.009 16.4 0.4 6.2 3 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF52727.1 - 9.9e-08 31.6 9.4 0.00041 20.0 0.0 5.6 3 2 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 OWF52727.1 - 1.7e-06 27.8 12.2 0.19 12.4 0.0 7.7 7 1 0 7 7 7 2 Leucine Rich Repeat F-box PF00646.33 OWF52727.1 - 0.0043 16.9 1.5 0.68 9.9 0.0 3.7 3 1 0 3 3 3 1 F-box domain LRR_9 PF14580.6 OWF52727.1 - 0.11 12.0 1.1 7.2 6.1 0.1 2.7 1 1 1 3 3 3 0 Leucine-rich repeat RNA_pol_Rbc25 PF08292.12 OWF52728.1 - 2.2e-32 112.0 0.4 3.3e-32 111.4 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OWF52728.1 - 3.5e-17 62.5 0.1 6.7e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cupin_8 PF13621.6 OWF52729.1 - 1.1e-09 38.4 1.1 2.9e-08 33.7 0.3 2.3 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 OWF52729.1 - 6.9e-07 29.0 0.7 0.00078 19.0 0.1 2.1 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 OWF52729.1 - 0.0035 17.7 0.1 0.018 15.5 0.0 2.2 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OWF52729.1 - 0.055 13.2 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Cupin domain PGAP1 PF07819.13 OWF52730.1 - 8.1e-77 258.0 0.0 1.1e-76 257.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 OWF52730.1 - 2.8e-05 24.1 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OWF52730.1 - 0.00027 20.7 0.0 0.00077 19.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF52730.1 - 0.00039 21.1 0.1 0.0013 19.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PHB_acc PF05233.13 OWF52730.1 - 0.0012 18.8 1.2 0.0067 16.4 0.2 2.4 2 0 0 2 2 2 1 PHB accumulation regulatory domain Hydrolase_4 PF12146.8 OWF52730.1 - 0.017 14.4 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 OWF52730.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Nudc_N PF14050.6 OWF52731.1 - 3.2e-23 81.5 0.0 6.9e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 OWF52731.1 - 7.5e-12 46.1 3.3 1.3e-11 45.4 3.3 1.4 1 0 0 1 1 1 1 CS domain Ribosomal_L16 PF00252.18 OWF52732.1 - 3e-42 143.7 0.0 3.7e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Malate_DH PF12434.8 OWF52732.1 - 0.12 12.4 0.3 0.25 11.4 0.3 1.4 1 0 0 1 1 1 0 Malate dehydrogenase enzyme RUN PF02759.19 OWF52733.1 - 1.4e-22 80.1 1.1 4.8e-22 78.4 0.5 2.3 2 0 0 2 2 2 1 RUN domain PX PF00787.24 OWF52733.1 - 5.4e-16 58.6 3.0 2.2e-15 56.6 3.0 2.0 1 0 0 1 1 1 1 PX domain DUF4140 PF13600.6 OWF52733.1 - 0.17 12.3 6.3 0.18 12.2 3.7 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Josephin PF02099.17 OWF52734.1 - 5.5e-26 91.6 1.4 2.3e-24 86.4 0.1 2.5 2 1 0 2 2 2 1 Josephin NPR3 PF03666.13 OWF52734.1 - 2.5 6.8 7.7 4.1 6.1 7.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GTP_EFTU PF00009.27 OWF52735.1 - 6.9e-25 87.7 0.1 1.2e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OWF52735.1 - 8.6e-09 35.7 0.6 3.5e-08 33.7 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 OWF52735.1 - 0.001 19.3 0.1 0.0032 17.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OWF52735.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OWF52735.1 - 0.0017 18.1 0.1 2 8.2 0.0 3.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OWF52735.1 - 0.052 13.6 0.1 0.39 10.8 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 OWF52735.1 - 0.057 12.9 0.2 7.7 5.9 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Aminotran_3 PF00202.21 OWF52736.1 - 4.6e-105 351.6 0.0 5.4e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.21 OWF52737.1 - 1e-108 363.6 0.0 1.2e-108 363.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III LIM PF00412.22 OWF52738.1 - 7.1e-32 109.4 28.4 3.5e-13 49.5 2.1 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 OWF52738.1 - 2e-14 53.7 0.0 3.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF52738.1 - 5e-09 35.9 0.1 1.2e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 OWF52738.1 - 3.2e-07 31.4 12.8 4.6e-05 24.4 0.4 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4749) PDZ_2 PF13180.6 OWF52738.1 - 0.0024 18.2 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain AAA PF00004.29 OWF52739.1 - 2.1e-11 44.4 0.3 0.0031 17.9 0.0 5.4 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OWF52739.1 - 6.8e-08 32.6 0.0 4.7e-06 26.6 0.0 3.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OWF52739.1 - 6.6e-05 22.5 0.1 0.079 12.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 OWF52739.1 - 0.00056 20.0 3.4 0.18 11.9 0.0 4.5 5 0 0 5 5 4 1 Sigma-54 interaction domain AAA_14 PF13173.6 OWF52739.1 - 0.00083 19.4 0.5 0.015 15.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 OWF52739.1 - 0.0012 19.4 0.1 0.059 13.9 0.1 3.7 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 OWF52739.1 - 0.008 16.5 3.1 4.5 7.6 0.3 5.1 4 1 0 4 4 4 1 AAA domain AAA_16 PF13191.6 OWF52739.1 - 0.03 14.7 0.6 1.3 9.3 0.1 3.5 3 0 0 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 OWF52739.1 - 0.037 13.9 0.0 0.037 13.9 0.0 4.7 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OWF52739.1 - 0.045 13.5 0.1 6.4 6.4 0.4 3.6 4 0 0 4 4 4 0 AAA domain MCM PF00493.23 OWF52739.1 - 0.15 11.1 3.9 4.3 6.4 0.1 3.7 4 0 0 4 4 4 0 MCM P-loop domain Phage_CI_repr PF07022.13 OWF52739.1 - 0.16 12.1 0.0 0.63 10.2 0.0 2.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain NACHT PF05729.12 OWF52739.1 - 0.17 11.8 4.5 3.6 7.5 0.1 3.9 4 0 0 4 4 4 0 NACHT domain RNA_helicase PF00910.22 OWF52739.1 - 0.21 12.0 5.6 3 8.3 0.0 4.5 5 0 0 5 5 4 0 RNA helicase ubiquitin PF00240.23 OWF52740.1 - 3.6e-08 33.0 0.1 1.2e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin family TerD PF02342.18 OWF52740.1 - 7.8e-05 22.2 0.0 0.00061 19.3 0.0 2.0 1 1 1 2 2 2 1 TerD domain DUF2407 PF10302.9 OWF52740.1 - 0.041 14.4 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain G-patch PF01585.23 OWF52741.1 - 1.2e-11 44.3 0.7 2.3e-11 43.4 0.7 1.5 1 0 0 1 1 1 1 G-patch domain Ank_2 PF12796.7 OWF52741.1 - 3.4e-09 37.2 0.0 6.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF52741.1 - 2.1e-05 24.8 0.1 0.00029 21.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OWF52741.1 - 5.7e-05 23.2 0.0 0.015 15.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OWF52741.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF52741.1 - 0.0034 17.7 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2197 PF09963.9 OWF52741.1 - 0.18 12.1 1.0 0.5 10.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) BLUF PF04940.12 OWF52742.1 - 0.057 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Sensors of blue-light using FAD Alpha_L_fucos PF01120.17 OWF52743.1 - 6.8e-36 124.4 2.4 8.7e-36 124.1 2.4 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Alpha_L_fucos PF01120.17 OWF52744.1 - 2.8e-58 198.1 0.6 3.4e-58 197.8 0.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF52744.1 - 7e-25 87.4 0.0 1.3e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 OWF52744.1 - 0.002 18.2 0.2 0.0092 16.1 0.2 2.0 1 1 1 2 2 2 1 Lactococcus bacteriophage putative transcription regulator Kazal_2 PF07648.15 OWF52745.1 - 5.7e-33 112.8 36.8 2.4e-11 43.6 4.5 4.4 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF52745.1 - 1.3e-25 89.1 40.4 4.3e-10 39.4 5.2 4.7 4 1 1 5 5 5 4 Kazal-type serine protease inhibitor domain Arf PF00025.21 OWF52746.1 - 1.2e-62 210.5 0.0 1.3e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OWF52746.1 - 7e-09 35.3 0.1 1.6e-06 27.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OWF52746.1 - 2.8e-08 33.4 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OWF52746.1 - 3e-08 33.9 0.0 6.9e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF52746.1 - 7e-08 32.2 0.0 7.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OWF52746.1 - 8.1e-07 29.1 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF52746.1 - 1.5e-05 24.4 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 OWF52746.1 - 0.00064 19.4 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CtaG_Cox11 PF04442.14 OWF52747.1 - 1.3e-51 174.6 0.2 1.8e-51 174.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Fascin PF06268.13 OWF52748.1 - 3.8e-61 204.2 1.0 3.4e-17 62.7 0.0 5.1 3 1 2 5 5 5 5 Fascin domain FRG1 PF06229.12 OWF52748.1 - 2.4e-14 53.5 3.6 0.00024 20.9 0.0 5.9 2 1 4 6 6 6 4 FRG1-like domain FGF PF00167.18 OWF52748.1 - 0.003 17.7 0.2 1.5 8.9 0.0 3.6 4 1 0 4 4 4 1 Fibroblast growth factor Adeno_E3_CR1 PF02440.15 OWF52748.1 - 0.047 13.5 0.3 6.4 6.6 0.0 3.3 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 RicinB_lectin_2 PF14200.6 OWF52748.1 - 0.32 11.8 4.8 31 5.4 0.0 4.5 3 2 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like zf-UDP PF14569.6 OWF52751.1 - 0.075 13.2 22.2 3.4 7.8 0.7 5.2 1 1 5 6 6 6 0 Zinc-binding RING-finger Death PF00531.22 OWF52752.1 - 7.2e-15 54.9 0.0 5.5e-06 26.4 0.0 2.8 2 0 0 2 2 2 2 Death domain COR PF16095.5 OWF52752.1 - 3.4e-14 53.1 0.1 9.5e-14 51.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF52752.1 - 9.8e-10 38.7 0.0 2.6e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF52752.1 - 3.2e-06 26.8 0.1 0.0037 16.9 0.0 2.4 2 0 0 2 2 2 2 Ras family Ank_2 PF12796.7 OWF52752.1 - 2.9e-05 24.5 0.0 0.00023 21.7 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Arf PF00025.21 OWF52752.1 - 0.0035 16.8 0.0 0.027 13.9 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OWF52752.1 - 0.017 14.9 0.3 0.081 12.7 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OWF52752.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OWF52752.1 - 0.046 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.6 OWF52752.1 - 0.14 12.8 0.0 2.7 8.7 0.0 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) WD40 PF00400.32 OWF52753.1 - 5.4e-38 128.3 7.4 1.9e-07 31.7 0.4 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF52753.1 - 9.6e-15 54.7 0.1 0.00019 21.6 0.0 5.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF52753.1 - 7.6e-13 48.1 3.9 0.0015 17.5 0.1 3.8 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 OWF52753.1 - 1.9e-12 46.6 0.2 3.7e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 OWF52753.1 - 1.7e-07 30.3 0.2 0.02 13.5 0.1 3.4 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.12 OWF52753.1 - 0.00057 19.7 0.0 0.14 12.2 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat LisH_2 PF16045.5 OWF52753.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 LisH Nucleoporin_N PF08801.11 OWF52753.1 - 0.024 13.4 0.1 7.6 5.1 0.0 3.8 2 2 2 4 4 4 0 Nup133 N terminal like Hira PF07569.11 OWF52753.1 - 0.031 14.0 0.8 1.7 8.3 0.0 3.6 5 0 0 5 5 5 0 TUP1-like enhancer of split PALB2_WD40 PF16756.5 OWF52753.1 - 0.06 12.3 0.7 1.8 7.4 0.0 3.2 2 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain FUSC PF04632.12 OWF52754.1 - 2.5 6.5 6.8 0.21 10.1 2.0 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family APC_r PF05923.12 OWF52755.1 - 2.8e-74 243.5 40.5 1e-10 41.1 0.2 12.1 11 0 0 11 11 11 10 APC repeat APC_rep PF18797.1 OWF52755.1 - 1.7e-28 99.3 0.2 2.5e-27 95.6 0.2 3.3 1 0 0 1 1 1 1 Adenomatous polyposis coli (APC) repeat Arm PF00514.23 OWF52755.1 - 3.4e-19 68.2 11.0 3.3e-05 23.8 0.2 7.5 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Suppressor_APC PF11414.8 OWF52755.1 - 3.5e-11 43.0 1.8 3.5e-11 43.0 1.8 4.2 3 1 1 4 4 4 1 Adenomatous polyposis coli tumour suppressor protein APC_15aa PF05972.11 OWF52755.1 - 2.2e-09 37.0 21.1 0.00091 19.3 0.7 6.1 6 0 0 6 6 6 2 APC 15 residue motif SAMP PF05924.11 OWF52755.1 - 8.7e-09 34.4 5.2 0.00017 20.8 0.5 3.1 2 0 0 2 2 2 2 SAMP Motif DUF4170 PF13773.6 OWF52756.1 - 0.19 11.9 0.0 23 5.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4170) Med15 PF09606.10 OWF52757.1 - 6.4e-19 68.2 0.3 7.1e-19 68.0 0.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal KIX PF02172.16 OWF52757.1 - 0.0017 18.6 0.2 0.0029 17.8 0.1 1.4 1 1 0 1 1 1 1 KIX domain KIX_2 PF16987.5 OWF52757.1 - 0.077 13.0 0.3 0.13 12.3 0.3 1.5 1 1 0 1 1 1 0 KIX domain Macoilin PF09726.9 OWF52758.1 - 5 5.6 21.7 6.3 5.2 21.7 1.0 1 0 0 1 1 1 0 Macoilin family zf-C3HC4_3 PF13920.6 OWF52759.1 - 1.8e-13 50.1 13.3 2.8e-13 49.5 13.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF52759.1 - 5.4e-08 32.6 10.4 9.1e-08 31.9 10.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF52759.1 - 4.2e-05 23.8 11.3 8.3e-05 22.8 11.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF52759.1 - 0.022 14.7 11.0 0.052 13.5 10.9 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_14 PF17978.1 OWF52759.1 - 0.68 10.4 10.4 0.059 13.8 4.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GST_C_6 PF17171.4 OWF52760.1 - 7e-19 67.4 0.0 9.6e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF52760.1 - 5.5e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF52760.1 - 0.0073 16.5 0.0 0.0099 16.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF52760.1 - 0.0078 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PCP_red PF08369.10 OWF52760.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit PhyH PF05721.13 OWF52761.1 - 3.2e-30 106.0 0.0 6e-30 105.1 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OWF52761.1 - 0.0027 18.1 0.6 0.0064 16.9 0.0 1.9 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase VWD PF00094.25 OWF52762.1 - 5.1e-81 270.6 17.1 2.3e-29 102.7 1.2 4.2 3 0 0 3 3 3 3 von Willebrand factor type D domain Gal_Lectin PF02140.18 OWF52762.1 - 2.9e-61 203.9 27.4 1.7e-23 82.8 3.5 7.8 7 0 0 7 7 7 3 Galactose binding lectin domain C8 PF08742.11 OWF52762.1 - 9.6e-32 109.2 26.1 2.9e-15 56.4 3.9 7.7 9 0 0 9 9 9 3 C8 domain Methyltransf_FA PF12248.8 OWF52762.1 - 4.3e-19 68.7 1.5 7.6e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 Farnesoic acid 0-methyl transferase TIL PF01826.17 OWF52762.1 - 2.5e-18 66.1 36.9 1.1e-08 35.2 9.7 13.0 11 2 2 13 13 13 3 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 OWF52762.1 - 1.3e-12 47.7 119.3 2.2e-05 24.6 2.4 11.7 10 1 1 11 11 11 7 EGF domain EGF_CA PF07645.15 OWF52762.1 - 0.00032 20.8 6.8 0.00032 20.8 6.8 11.9 10 1 1 11 11 11 3 Calcium-binding EGF domain CzcE PF16986.5 OWF52762.1 - 0.00064 20.0 0.0 24 5.4 0.0 3.8 3 0 0 3 3 3 0 Heavy-metal resistance protein CzcE EGF PF00008.27 OWF52762.1 - 0.0014 18.9 1.5 0.0014 18.9 1.5 10.0 9 0 0 9 9 9 2 EGF-like domain SH3_10 PF17902.1 OWF52762.1 - 0.0028 17.7 1.0 26 5.0 0.0 3.7 3 0 0 3 3 3 0 SH3 domain zf-H2C2_2 PF13465.6 OWF52763.1 - 2e-14 53.2 22.8 2.8e-07 30.6 1.4 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 OWF52763.1 - 9.8e-14 51.0 19.1 1.4e-05 25.3 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF52763.1 - 4e-08 33.4 23.5 0.012 16.3 0.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OWF52763.1 - 0.026 14.4 9.7 1.2 9.1 0.4 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 OWF52763.1 - 0.033 14.5 3.8 30 5.1 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 OWF52763.1 - 0.074 13.1 7.1 0.19 11.8 3.3 2.6 1 1 1 2 2 2 0 BED zinc finger Zf_RING PF16744.5 OWF52763.1 - 0.083 13.0 2.3 2.4 8.3 0.1 2.5 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C2H2_6 PF13912.6 OWF52763.1 - 0.17 11.9 8.3 4 7.5 1.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 OWF52763.1 - 3.8 8.0 7.2 26 5.4 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Laminin_G_1 PF00054.23 OWF52764.1 - 2.3e-19 69.9 3.0 6e-13 49.2 0.1 3.7 3 0 0 3 3 3 2 Laminin G domain Laminin_G_2 PF02210.24 OWF52764.1 - 2.4e-18 66.9 4.5 7e-14 52.5 0.1 3.4 3 0 0 3 3 3 2 Laminin G domain Med9 PF07544.13 OWF52764.1 - 0.013 15.5 1.7 0.28 11.3 0.1 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2310 PF10071.9 OWF52764.1 - 0.083 12.2 1.6 0.25 10.6 0.1 2.4 2 0 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) DASH_Dam1 PF08653.10 OWF52764.1 - 0.25 11.2 2.5 37 4.2 0.1 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 LUC7 PF03194.15 OWF52764.1 - 0.63 9.7 6.9 0.25 11.0 2.5 2.4 2 0 0 2 2 2 0 LUC7 N_terminus Baculo_PEP_C PF04513.12 OWF52764.1 - 4 7.5 12.3 59 3.7 0.4 4.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ASC PF00858.24 OWF52765.1 - 4.2e-89 299.5 10.1 4.8e-89 299.3 10.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Rhodanese PF00581.20 OWF52766.1 - 1.5e-08 35.1 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain BRCA-2_OB3 PF09104.10 OWF52766.1 - 0.051 13.2 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 SPATA48 PF15073.6 OWF52767.1 - 5.9e-09 36.3 4.4 0.012 16.0 0.1 4.2 1 1 3 4 4 4 3 Spermatogenesis-associated protein 48 DUF5433 PF17498.2 OWF52767.1 - 5.6e-06 26.5 11.3 0.93 9.8 0.2 4.5 1 1 3 4 4 4 4 Family of unknown function (DUF5433) DUF1891 PF09004.10 OWF52767.1 - 9.8e-06 25.1 6.5 11 5.7 0.1 6.6 3 2 2 7 7 7 2 Domain of unknown function (DUF1891) RibD_C PF01872.17 OWF52767.1 - 0.0024 17.8 0.0 13 5.5 0.0 3.4 2 2 1 3 3 3 2 RibD C-terminal domain HET-S PF17108.5 OWF52767.1 - 0.0038 16.9 16.0 2.1e+02 1.8 0.0 10.6 13 0 0 13 13 13 0 N-terminal small S protein of HET, non-prionic APOC4 PF15119.6 OWF52767.1 - 0.16 12.3 0.0 9 6.6 0.0 2.8 1 1 2 3 3 3 0 Apolipoprotein C4 Shugoshin_N PF07558.11 OWF52767.1 - 5.4 7.0 21.3 42 4.1 0.1 6.1 3 2 3 8 8 8 0 Shugoshin N-terminal coiled-coil region SPATA48 PF15073.6 OWF52768.1 - 4.6e-10 39.9 15.0 0.0024 18.2 1.9 6.2 1 1 3 5 5 5 4 Spermatogenesis-associated protein 48 DUF1891 PF09004.10 OWF52768.1 - 1.2e-07 31.3 10.7 7.5 6.3 0.0 8.3 6 2 4 11 11 11 3 Domain of unknown function (DUF1891) DUF5433 PF17498.2 OWF52768.1 - 6.5e-05 23.1 15.2 0.85 9.9 0.3 5.9 1 1 3 5 5 5 3 Family of unknown function (DUF5433) Vitellogenin_N PF01347.22 OWF52768.1 - 0.098 11.0 2.7 9.5 4.5 0.1 3.5 1 1 1 3 3 3 0 Lipoprotein amino terminal region Syncollin PF15138.6 OWF52768.1 - 0.099 12.8 0.3 1.4e+02 2.7 0.0 3.8 2 2 2 5 5 5 0 Syncollin Shugoshin_N PF07558.11 OWF52768.1 - 0.74 9.7 22.6 41 4.2 0.2 7.4 5 2 3 9 9 9 0 Shugoshin N-terminal coiled-coil region HET-S PF17108.5 OWF52768.1 - 2 8.2 19.2 2e+02 1.9 0.0 9.5 12 0 0 12 12 12 0 N-terminal small S protein of HET, non-prionic DUF1891 PF09004.10 OWF52769.1 - 0.0072 15.9 0.3 7.5 6.2 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF1891) HET-S PF17108.5 OWF52769.1 - 0.014 15.1 1.6 79 3.1 0.0 4.9 6 0 0 6 6 6 0 N-terminal small S protein of HET, non-prionic SPATA48 PF15073.6 OWF52769.1 - 0.022 15.1 1.5 0.28 11.5 0.3 2.7 1 1 1 2 2 2 0 Spermatogenesis-associated protein 48 DUF5433 PF17498.2 OWF52769.1 - 0.17 12.1 1.8 7.2 6.9 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5433) Shugoshin_N PF07558.11 OWF52769.1 - 1.1 9.1 3.4 4.9 7.1 0.3 2.8 2 1 2 4 4 4 0 Shugoshin N-terminal coiled-coil region Ribosomal_S18 PF01084.20 OWF52770.1 - 2.1e-17 63.0 0.0 4.5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 ELMO_CED12 PF04727.13 OWF52771.1 - 9.5e-33 113.8 0.0 2.4e-32 112.4 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DUF4603 PF15376.6 OWF52772.1 - 1.6e-28 98.8 9.8 1.6e-28 98.8 9.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4603) zf_CCCH_4 PF18345.1 OWF52772.1 - 0.00037 20.4 6.3 0.015 15.3 0.8 3.3 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 OWF52772.1 - 0.012 15.5 1.0 0.012 15.5 1.0 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 OWF52772.1 - 0.03 14.5 3.9 0.13 12.5 3.9 2.1 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 OWF52772.1 - 0.12 12.8 10.0 1.7 9.2 1.5 3.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TACC_C PF05010.14 OWF52774.1 - 8.6e-53 179.1 33.2 1.4e-52 178.5 33.2 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 OWF52774.1 - 0.0031 16.9 26.5 0.0031 16.9 26.5 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 OWF52774.1 - 0.0039 16.7 23.7 0.0039 16.7 23.7 2.9 2 1 2 4 4 4 2 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 OWF52774.1 - 0.015 15.8 14.3 0.015 15.8 14.3 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region EspB PF05802.11 OWF52774.1 - 0.055 13.5 8.4 0.081 12.9 7.2 2.0 1 1 0 1 1 1 0 Enterobacterial EspB protein EzrA PF06160.12 OWF52774.1 - 0.077 11.2 22.9 0.12 10.5 22.9 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 OWF52774.1 - 2.4 8.8 37.6 3.1 8.5 8.0 3.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 OWF52774.1 - 4.7 5.0 17.8 6.7 4.5 17.8 1.1 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 OWF52774.1 - 5.2 7.6 12.0 7 7.1 0.1 4.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) GDI PF00996.18 OWF52775.1 - 1.7e-174 580.4 0.2 2e-174 580.2 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 OWF52775.1 - 0.046 13.0 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase ADP_ribosyl_GH PF03747.14 OWF52776.1 - 1.3e-61 208.9 0.0 1.6e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Flavodoxin_3 PF12641.7 OWF52776.1 - 0.09 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Flavodoxin domain UPF0262 PF06793.12 OWF52776.1 - 0.12 12.5 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) ADP_ribosyl_GH PF03747.14 OWF52777.1 - 3.5e-56 191.1 0.1 4.5e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Glyco_transf_10 PF00852.19 OWF52777.1 - 0.13 11.9 0.1 0.33 10.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term WBP-1 PF11669.8 OWF52778.1 - 6e-07 30.1 1.9 6.7e-07 29.9 0.3 1.8 1 1 1 2 2 2 1 WW domain-binding protein 1 EphA2_TM PF14575.6 OWF52778.1 - 1.1e-05 26.2 0.0 0.00011 23.0 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OWF52778.1 - 1.6e-05 25.3 1.6 2.2e-05 24.8 1.6 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CYYR1 PF10873.8 OWF52778.1 - 0.00014 22.3 11.9 0.00026 21.5 11.9 1.4 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Cadherin_C_2 PF16492.5 OWF52778.1 - 0.00072 20.3 1.0 0.0021 18.7 0.3 2.1 2 1 0 2 2 2 1 Cadherin cytoplasmic C-terminal RCR PF12273.8 OWF52778.1 - 0.0017 19.0 0.0 0.0034 18.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Protocadherin PF08374.11 OWF52778.1 - 0.002 18.1 1.8 0.0025 17.9 1.4 1.4 1 1 0 1 1 1 1 Protocadherin SARAF PF06682.12 OWF52778.1 - 0.0027 17.4 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Comm PF15957.5 OWF52778.1 - 0.003 17.9 1.7 0.0085 16.4 0.1 2.0 1 1 1 2 2 2 1 Commissureless Vpu PF00558.19 OWF52778.1 - 0.0035 17.1 2.4 0.0075 16.0 2.4 1.5 1 0 0 1 1 1 1 Vpu protein Podoplanin PF05808.11 OWF52778.1 - 0.0071 16.5 0.3 0.0099 16.0 0.3 1.3 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 OWF52778.1 - 0.011 15.6 6.4 0.061 13.2 3.5 2.1 1 1 0 2 2 2 0 TMEM154 protein family FAM176 PF14851.6 OWF52778.1 - 0.017 14.8 4.9 0.099 12.3 0.8 2.1 1 1 0 2 2 2 0 FAM176 family SP_C-Propep PF08999.10 OWF52778.1 - 0.028 14.2 2.9 0.028 14.2 2.9 2.0 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide SIT PF15330.6 OWF52778.1 - 0.031 14.7 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMIE PF16038.5 OWF52778.1 - 0.032 14.1 2.3 0.032 14.1 2.3 2.0 2 0 0 2 2 2 0 TMIE protein DUF5385 PF17359.2 OWF52778.1 - 0.052 13.1 0.2 0.077 12.5 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Renin_r PF07850.14 OWF52778.1 - 0.093 13.3 0.0 0.24 12.0 0.0 1.6 1 1 1 2 2 2 0 Renin receptor-like protein TMEM132D_C PF15706.5 OWF52778.1 - 0.11 12.3 1.1 0.8 9.5 0.2 2.1 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ASFV_J13L PF05568.11 OWF52778.1 - 0.12 12.2 0.7 0.18 11.6 0.1 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein Sigma_reg_N PF13800.6 OWF52778.1 - 0.14 12.5 0.1 0.27 11.5 0.0 1.5 2 0 0 2 2 1 0 Sigma factor regulator N-terminal DUF3357 PF11837.8 OWF52778.1 - 0.16 12.4 0.1 0.7 10.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) TRP PF06011.12 OWF52778.1 - 0.17 10.6 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF2371 PF10177.9 OWF52778.1 - 0.19 11.9 3.0 0.15 12.2 0.4 1.9 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) Baculo_11_kDa PF06143.11 OWF52778.1 - 0.32 10.6 3.1 0.33 10.5 2.0 1.5 2 0 0 2 2 1 0 Baculovirus 11 kDa family LRR19-TM PF15176.6 OWF52778.1 - 0.46 10.5 1.8 0.51 10.4 0.9 1.5 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Mid2 PF04478.12 OWF52778.1 - 0.48 10.3 5.6 0.7 9.7 3.8 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor ECSCR PF15820.5 OWF52778.1 - 0.66 9.8 10.7 0.092 12.6 5.2 2.0 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF3827 PF12877.7 OWF52778.1 - 0.68 8.2 4.4 0.88 7.9 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Syndecan PF01034.20 OWF52778.1 - 4.6 7.2 7.9 0.42 10.6 2.8 1.9 2 0 0 2 2 2 0 Syndecan domain Cadherin_C_2 PF16492.5 OWF52779.1 - 0.00066 20.4 0.0 0.0017 19.1 0.0 1.8 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal WBP-1 PF11669.8 OWF52779.1 - 0.00082 20.0 0.2 0.0016 19.0 0.2 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 SecG PF03840.14 OWF52779.1 - 0.0062 16.6 1.9 0.022 14.8 1.9 1.8 1 1 0 1 1 1 1 Preprotein translocase SecG subunit MLANA PF14991.6 OWF52779.1 - 0.016 15.5 0.1 0.03 14.6 0.1 1.5 1 1 0 1 1 1 0 Protein melan-A Shisa PF13908.6 OWF52779.1 - 0.096 12.9 0.3 0.096 12.9 0.3 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator TMEM51 PF15345.6 OWF52779.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3043 PF11241.8 OWF52779.1 - 3 7.8 6.4 2.7 8.0 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) 7tm_1 PF00001.21 OWF52781.1 - 3.8e-20 72.3 21.6 5.6e-20 71.8 21.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF52781.1 - 0.00011 21.9 22.0 0.00011 21.9 22.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Presenilin PF01080.17 OWF52781.1 - 0.0014 17.5 2.8 0.0014 17.5 2.8 2.8 2 1 0 2 2 2 1 Presenilin Baculo_11_kDa PF06143.11 OWF52781.1 - 0.16 11.6 1.9 0.32 10.6 0.6 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family TBPIP PF07106.13 OWF52782.1 - 0.029 14.3 10.9 1.6e+02 2.3 0.0 9.1 7 0 0 7 7 7 0 TBPIP/Hop2 winged helix domain RAG2_PHD PF13341.6 OWF52782.1 - 0.55 10.3 91.2 33 4.6 0.1 25.8 5 1 29 36 36 36 0 RAG2 PHD domain Xan_ur_permease PF00860.20 OWF52785.1 - 5.4e-63 213.0 13.1 9.4e-63 212.2 13.1 1.3 1 0 0 1 1 1 1 Permease family PH PF00169.29 OWF52786.1 - 1e-09 38.8 0.4 2.2e-09 37.8 0.4 1.5 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 OWF52786.1 - 3.1e-08 33.6 0.8 5.7e-08 32.8 0.2 1.8 2 0 0 2 2 2 1 SH2 domain COX15-CtaA PF02628.15 OWF52787.1 - 4.8e-110 367.6 5.3 6e-110 367.3 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein p450 PF00067.22 OWF52789.1 - 9.3e-96 321.4 0.5 1.1e-95 321.2 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIM PF00412.22 OWF52791.1 - 9.3e-11 41.8 9.5 1.1e-10 41.6 9.5 1.1 1 0 0 1 1 1 1 LIM domain FlgN PF05130.12 OWF52793.1 - 0.042 14.4 0.1 0.069 13.7 0.1 1.3 1 0 0 1 1 1 0 FlgN protein CDH-cyt PF16010.5 OWF52793.1 - 0.3 10.7 7.2 0.72 9.5 7.2 1.6 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase ABC2_membrane_3 PF12698.7 OWF52793.1 - 0.62 9.1 3.1 2.2 7.3 3.0 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Exo_endo_phos PF03372.23 OWF52794.1 - 3.2e-05 23.6 0.1 6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PWI PF01480.17 OWF52794.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 PWI domain TFIIS_C PF01096.18 OWF52795.1 - 5.5e-15 54.9 4.6 5.5e-15 54.9 4.6 3.3 4 0 0 4 4 3 1 Transcription factor S-II (TFIIS) MqsA_antitoxin PF15731.5 OWF52795.1 - 0.0033 17.5 0.4 0.44 10.7 0.0 2.1 2 0 0 2 2 2 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA RNA_POL_M_15KD PF02150.16 OWF52795.1 - 0.006 16.4 1.4 0.006 16.4 1.4 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf_Rg PF17915.1 OWF52795.1 - 0.0062 15.9 2.4 2.1 7.8 0.1 3.1 3 0 0 3 3 3 1 Reverse gyrase zinc finger Zn_Tnp_IS1595 PF12760.7 OWF52795.1 - 0.01 15.8 13.5 0.6 10.1 1.4 2.8 2 1 0 2 2 2 2 Transposase zinc-ribbon domain zf-CSL PF05207.13 OWF52795.1 - 0.014 15.1 6.0 0.24 11.2 0.5 2.4 2 1 0 2 2 2 0 CSL zinc finger RPA_interact_C PF14768.6 OWF52795.1 - 0.026 15.1 4.2 0.11 13.1 4.2 2.1 1 1 0 1 1 1 0 Replication protein A interacting C-terminal DUF3716 PF12511.8 OWF52795.1 - 0.034 14.2 0.6 0.034 14.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) zf-IS66 PF13005.7 OWF52795.1 - 0.035 14.5 5.1 9.9 6.7 0.0 3.8 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DZR PF12773.7 OWF52795.1 - 0.042 13.9 0.9 0.042 13.9 0.9 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_7 PF02591.15 OWF52795.1 - 0.044 14.0 4.1 18 5.6 0.1 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain XAF1_C PF18608.1 OWF52795.1 - 0.044 13.3 0.9 0.044 13.3 0.9 2.5 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain zf-TFIIB PF13453.6 OWF52795.1 - 0.052 12.9 1.6 0.052 12.9 1.6 2.7 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF2318 PF10080.9 OWF52795.1 - 0.087 13.0 0.3 0.087 13.0 0.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 OWF52795.1 - 0.099 12.7 6.3 8.4 6.5 6.3 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C4_Topoisom PF01396.19 OWF52795.1 - 0.11 12.3 13.0 0.4 10.5 3.7 3.2 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF1610 PF07754.11 OWF52795.1 - 0.17 11.9 0.3 0.17 11.9 0.3 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF1610) zinc_ribbon_4 PF13717.6 OWF52795.1 - 0.17 11.8 9.1 21 5.1 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 OWF52795.1 - 0.18 11.8 8.2 2.8 8.0 1.4 2.7 2 1 1 3 3 3 0 zinc-ribbons NRDD PF13597.6 OWF52795.1 - 0.21 10.3 3.5 1.2 7.8 0.0 2.2 1 1 2 3 3 3 0 Anaerobic ribonucleoside-triphosphate reductase zf-ribbon_3 PF13248.6 OWF52795.1 - 0.22 11.0 14.2 1 8.8 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Baculo_LEF5_C PF11792.8 OWF52795.1 - 0.22 11.2 1.6 0.75 9.5 1.7 1.9 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain A2L_zn_ribbon PF08792.10 OWF52795.1 - 0.25 11.1 13.4 0.63 9.8 0.1 3.7 4 0 0 4 4 4 0 A2L zinc ribbon domain IBR PF01485.21 OWF52795.1 - 0.41 10.9 9.6 3.5 7.9 1.2 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Ribosomal_S27e PF01667.17 OWF52795.1 - 0.44 10.3 0.1 0.44 10.3 0.1 3.8 3 1 0 3 3 3 0 Ribosomal protein S27 zf_C2H2_10 PF18414.1 OWF52795.1 - 0.52 9.9 11.3 9.9 5.8 0.6 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger OrfB_Zn_ribbon PF07282.11 OWF52795.1 - 0.52 10.3 8.2 1.3 9.0 0.1 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.6 OWF52795.1 - 0.61 10.5 10.7 0.17 12.3 1.3 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar Ogr_Delta PF04606.12 OWF52795.1 - 0.61 10.1 10.0 0.42 10.6 3.1 2.9 2 2 1 3 3 3 0 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.6 OWF52795.1 - 1.5 8.6 16.1 10 6.0 3.2 4.0 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 OWF52795.1 - 1.9 9.3 11.2 1.2 9.9 0.7 3.3 2 1 1 3 3 3 0 zinc-ribbon family Nop10p PF04135.12 OWF52795.1 - 2.2 8.4 6.1 21 5.3 0.1 2.7 2 1 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Zn_Tnp_IS1 PF03811.13 OWF52795.1 - 2.3 8.0 9.3 8.1 6.3 0.1 3.6 4 0 0 4 4 4 0 InsA N-terminal domain DnaJ_CXXCXGXG PF00684.19 OWF52795.1 - 2.7 8.4 10.3 0.18 12.2 1.8 2.5 2 1 0 2 2 2 0 DnaJ central domain zinc_ribbon_10 PF10058.9 OWF52795.1 - 3.1 7.6 8.2 3.1 7.6 2.2 3.3 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 OWF52795.1 - 3.5 7.7 10.7 24 5.0 0.8 3.5 3 1 0 3 3 3 0 PhnA Zinc-Ribbon UPF0547 PF10571.9 OWF52795.1 - 4.8 7.4 17.6 5.6 7.1 0.1 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-ZPR1 PF03367.13 OWF52795.1 - 9.3 6.1 8.1 0.66 9.8 1.1 2.2 3 0 0 3 3 2 0 ZPR1 zinc-finger domain TF_Zn_Ribbon PF08271.12 OWF52795.1 - 9.9 5.8 17.7 1.8 8.1 0.3 3.9 2 2 1 3 3 3 0 TFIIB zinc-binding Trm112p PF03966.16 OWF52796.1 - 3e-17 62.9 0.0 3.6e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Med5 PF08689.10 OWF52796.1 - 0.19 9.5 0.0 0.28 9.0 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 Filament PF00038.21 OWF52797.1 - 3.1e-60 204.4 61.9 2.8e-58 198.0 61.9 2.3 1 1 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 OWF52797.1 - 0.00016 20.6 52.5 0.021 13.8 15.3 3.7 1 1 3 4 4 4 4 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 OWF52797.1 - 0.00027 18.9 59.4 0.0015 16.4 37.4 2.2 1 1 1 2 2 2 2 Myosin tail EzrA PF06160.12 OWF52797.1 - 0.00031 19.1 49.4 0.0056 14.9 9.7 3.5 1 1 2 3 3 3 2 Septation ring formation regulator, EzrA DUF4349 PF14257.6 OWF52797.1 - 0.0012 18.3 10.6 0.0012 18.3 10.6 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4349) TPR_MLP1_2 PF07926.12 OWF52797.1 - 0.0013 18.7 4.8 0.0013 18.7 4.8 5.3 1 1 5 6 6 6 1 TPR/MLP1/MLP2-like protein MAD PF05557.13 OWF52797.1 - 0.0026 16.2 62.4 0.0069 14.8 24.0 3.2 1 1 2 3 3 3 2 Mitotic checkpoint protein CENP-F_leu_zip PF10473.9 OWF52797.1 - 0.0027 17.7 62.2 0.0075 16.3 6.7 4.5 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 OWF52797.1 - 0.0037 17.6 17.0 0.0037 17.6 17.0 4.2 1 1 3 4 4 3 1 Domain of unknown function (DUF4200) DUF5082 PF16888.5 OWF52797.1 - 0.011 16.0 38.3 0.045 14.0 3.4 4.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 OWF52797.1 - 0.015 15.3 29.9 0.079 13.0 3.8 4.7 3 2 2 5 5 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 OWF52797.1 - 0.018 14.1 38.6 0.084 11.9 8.1 2.9 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 OWF52797.1 - 0.024 14.5 57.4 0.039 13.8 18.5 3.7 1 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH HIP1_clath_bdg PF16515.5 OWF52797.1 - 0.025 15.2 11.8 0.025 15.2 11.8 4.8 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 OWF52797.1 - 0.034 14.7 65.6 0.61 10.6 7.8 5.2 1 1 3 4 4 4 0 Apg6 coiled-coil region ATG16 PF08614.11 OWF52797.1 - 0.082 13.1 55.6 0.026 14.7 24.4 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) bMG3 PF11974.8 OWF52797.1 - 0.089 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain GAS PF13851.6 OWF52797.1 - 0.14 11.5 60.2 3.4 7.0 6.1 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 OWF52797.1 - 0.26 8.7 50.0 0.14 9.7 20.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) DASH_Hsk3 PF08227.11 OWF52797.1 - 0.26 11.7 14.5 1.7 9.1 1.3 4.9 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Laminin_II PF06009.12 OWF52797.1 - 0.3 11.1 29.6 1.6 8.7 1.3 5.2 2 2 3 5 5 5 0 Laminin Domain II DUF4407 PF14362.6 OWF52797.1 - 0.97 8.7 36.7 1.3 8.3 12.6 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 OWF52797.1 - 0.99 8.7 56.4 0.083 12.2 17.7 3.7 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) CENP-H PF05837.12 OWF52797.1 - 1.4 9.4 45.9 0.67 10.4 9.5 4.4 3 1 1 4 4 4 0 Centromere protein H (CENP-H) HMMR_N PF15905.5 OWF52797.1 - 1.6 8.1 51.8 1.7 8.1 19.7 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FIVAR PF07554.13 OWF52797.1 - 2.3 9.0 9.5 7 7.5 0.3 4.3 4 1 1 5 5 4 0 FIVAR domain YabA PF06156.13 OWF52797.1 - 2.8 8.6 51.5 3.6 8.3 3.5 5.7 1 1 4 5 5 5 0 Initiation control protein YabA FPP PF05911.11 OWF52797.1 - 2.9 6.0 50.5 0.39 8.8 24.9 2.7 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Baculo_PEP_C PF04513.12 OWF52797.1 - 3.8 7.5 16.7 0.6 10.1 1.9 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 OWF52797.1 - 4 6.2 49.3 0.092 11.6 18.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) SlyX PF04102.12 OWF52797.1 - 6.6 7.4 41.5 2.8 8.6 3.8 6.7 2 2 5 7 7 7 0 SlyX TMPIT PF07851.13 OWF52797.1 - 7.6 5.7 38.2 0.84 8.8 3.4 3.8 1 1 1 3 3 3 0 TMPIT-like protein Leu_zip PF15294.6 OWF52797.1 - 8 5.9 49.5 0.088 12.3 14.1 3.2 1 1 2 3 3 3 0 Leucine zipper OATP PF03137.20 OWF52798.1 - 2.2e-109 366.3 22.3 5.4e-108 361.6 22.3 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF52798.1 - 5e-17 61.8 19.5 3.3e-15 55.9 15.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF52798.1 - 4.3e-06 26.7 12.0 1.1e-05 25.4 12.0 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF52798.1 - 0.0048 16.9 6.2 0.014 15.4 6.2 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain ATP-grasp_5 PF13549.6 OWF52798.1 - 0.26 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Glyco_transf_11 PF01531.16 OWF52799.1 - 1.6e-32 112.9 0.6 1.8e-32 112.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Glyco_transf_11 PF01531.16 OWF52800.1 - 6e-38 130.7 4.7 7.4e-38 130.4 4.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 Phage_Gp17 PF17549.2 OWF52800.1 - 0.03 14.3 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Gene Product 17 PC4 PF02229.16 OWF52801.1 - 1.9e-19 69.0 0.1 1.9e-10 40.2 0.3 2.4 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) zf-PARP PF00645.18 OWF52801.1 - 1.9e-07 31.8 0.2 5.3e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ADAM_CR_2 PF17771.1 OWF52802.1 - 7.7e-07 29.5 2.8 6.7e-06 26.5 2.7 2.6 2 0 0 2 2 2 1 ADAM cysteine-rich domain ARS2 PF04959.13 OWF52803.1 - 4.1e-61 206.8 4.8 4.1e-61 206.8 4.8 3.5 4 0 0 4 4 4 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 OWF52803.1 - 6.4e-39 132.5 5.7 2.6e-38 130.6 5.7 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) RRM_1 PF00076.22 OWF52803.1 - 0.00066 19.4 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sharpin_PH PF16764.5 OWF52804.1 - 0.0025 17.5 0.0 6.1 6.6 0.0 2.9 1 1 2 3 3 3 3 Sharpin PH domain Inhibitor_I29 PF08246.12 OWF52804.1 - 0.13 12.7 0.6 1.2e+02 3.2 0.0 3.8 1 1 3 4 4 4 0 Cathepsin propeptide inhibitor domain (I29) IL2RB_N1 PF18707.1 OWF52804.1 - 0.74 10.4 12.9 7.8e+02 0.7 12.9 2.9 1 1 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 7tm_1 PF00001.21 OWF52805.1 - 2.9e-17 62.9 19.3 3.8e-17 62.5 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF52805.1 - 1.3e-09 37.8 23.6 2.2e-08 33.7 23.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF52805.1 - 1.1e-05 25.2 13.1 1.1e-05 25.2 13.1 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 OWF52805.1 - 0.42 10.2 24.7 0.16 11.6 20.7 2.2 1 1 0 1 1 1 0 Srg family chemoreceptor HATPase_c_3 PF13589.6 OWF52806.1 - 0.0079 16.0 0.3 0.12 12.2 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Roc PF08477.13 OWF52807.1 - 2.6e-08 34.1 0.0 6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF52807.1 - 1.3e-07 31.6 0.1 3e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Death PF00531.22 OWF52807.1 - 7.8e-06 26.0 0.0 2.1e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Death domain Ras PF00071.22 OWF52807.1 - 0.00018 21.2 0.3 0.0013 18.3 0.0 2.4 3 0 0 3 3 3 1 Ras family Glyco_hydro_18 PF00704.28 OWF52808.1 - 6.9e-118 393.9 13.8 1.7e-76 257.9 1.8 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_14 PF01607.24 OWF52808.1 - 1.9e-09 37.5 7.3 4.1e-09 36.5 7.3 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain GvpH PF05455.11 OWF52808.1 - 0.88 9.6 3.2 0.83 9.7 0.2 2.4 3 0 0 3 3 3 0 GvpH Glyco_hydro_18 PF00704.28 OWF52809.1 - 1.2e-82 278.1 0.1 1.4e-82 277.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HMG_CoA_synt_N PF01154.17 OWF52811.1 - 0.079 12.8 0.2 0.2 11.5 0.1 1.6 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal AAA_12 PF13087.6 OWF52812.1 - 3.2e-40 137.9 1.6 5.1e-40 137.2 0.7 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OWF52812.1 - 3.1e-19 69.8 2.4 3.6e-18 66.3 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OWF52812.1 - 1.6e-07 31.7 0.1 3e-05 24.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF52812.1 - 5.4e-06 26.3 0.0 0.0034 17.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 OWF52812.1 - 0.00088 18.6 0.1 0.0069 15.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 OWF52812.1 - 0.0013 18.7 0.2 0.085 12.9 0.0 3.2 4 1 1 5 5 5 1 AAA domain (dynein-related subfamily) AAA PF00004.29 OWF52812.1 - 0.0055 17.1 0.3 0.069 13.6 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.6 OWF52812.1 - 0.019 14.3 0.1 0.32 10.3 0.2 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 OWF52812.1 - 0.077 13.0 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OWF52812.1 - 0.12 12.6 0.0 0.74 10.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 OWF52812.1 - 0.14 11.9 0.0 5.8 6.7 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 OWF52812.1 - 0.16 12.5 0.8 1.1 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Lectin_C PF00059.21 OWF52813.1 - 5.9e-11 43.1 2.6 5.9e-11 43.1 2.6 2.8 2 1 1 3 3 3 1 Lectin C-type domain PsbM PF05151.12 OWF52813.1 - 1.3 8.9 4.1 3 7.7 3.6 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) Dicty_REP PF05086.12 OWF52813.1 - 2.4 6.0 4.5 3.7 5.4 4.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ATG16 PF08614.11 OWF52813.1 - 3.9 7.6 6.8 6.2 7.0 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM184 PF15665.5 OWF52814.1 - 9.2e-09 35.4 45.4 1.8e-07 31.2 34.6 2.3 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B HMMR_N PF15905.5 OWF52814.1 - 0.00014 21.5 48.1 0.0065 16.0 8.0 3.3 1 1 2 3 3 3 3 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 OWF52814.1 - 0.0017 18.0 40.4 0.0017 18.0 40.4 2.0 1 1 1 2 2 2 2 Intermediate filament protein Fez1 PF06818.15 OWF52814.1 - 0.32 11.4 44.8 0.1 13.0 25.5 2.6 1 1 2 3 3 3 0 Fez1 IFT57 PF10498.9 OWF52814.1 - 0.65 8.9 39.0 3 6.7 0.1 2.9 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 OWF52814.1 - 0.71 9.9 25.3 1.3 9.0 7.6 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 OWF52814.1 - 1.1 9.3 49.0 5.6 7.0 22.5 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 OWF52814.1 - 1.2 8.6 47.7 0.39 10.1 25.7 3.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4472 PF14739.6 OWF52814.1 - 2.7 8.8 38.5 0.26 12.0 11.5 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) Hydantoinase_B PF02538.14 OWF52814.1 - 3.3 6.0 5.1 1.5 7.2 2.6 1.6 1 1 1 2 2 2 0 Hydantoinase B/oxoprolinase DivIVA PF05103.13 OWF52814.1 - 4.7 7.3 34.9 2 8.5 14.2 3.0 1 1 1 2 2 2 0 DivIVA protein DUF2746 PF10874.8 OWF52814.1 - 7.9 7.0 7.0 1.8 9.0 1.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2746) zf-H2C2_2 PF13465.6 OWF52815.1 - 9.2e-17 60.6 20.7 2.1e-09 37.4 1.2 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 OWF52815.1 - 1.2e-15 57.0 19.3 6.8e-05 23.1 3.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF52815.1 - 4.1e-11 42.7 17.6 0.00026 21.6 2.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 OWF52815.1 - 8.7e-05 23.1 5.7 0.011 16.3 0.2 3.4 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 OWF52815.1 - 0.0013 19.0 4.0 7 7.1 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF52815.1 - 0.002 18.4 4.6 0.15 12.5 0.4 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF52815.1 - 0.0028 17.9 5.1 0.006 16.9 4.5 1.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-Di19 PF05605.12 OWF52815.1 - 0.011 15.9 1.7 0.011 15.9 1.7 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 OWF52815.1 - 0.017 15.6 0.6 1.1 9.8 0.1 2.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 OWF52815.1 - 0.045 13.6 0.3 10 6.0 0.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 OWF52815.1 - 0.074 13.1 0.7 0.074 13.1 0.7 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OWF52815.1 - 0.22 11.6 3.3 9.2 6.4 0.3 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-WRNIP1_ubi PF18279.1 OWF52815.1 - 0.68 10.7 0.0 0.68 10.7 0.0 2.3 3 0 0 3 3 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-BED PF02892.15 OWF52815.1 - 1.2 9.2 9.7 7.5 6.7 1.2 2.9 2 1 1 3 3 3 0 BED zinc finger PAW PF04721.17 OWF52816.1 - 1.6e-69 233.7 0.9 2.1e-69 233.3 0.0 1.6 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 OWF52816.1 - 9.4e-21 73.6 0.0 2.2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.19 OWF52816.1 - 7.9e-15 55.3 1.0 4.1e-14 53.0 0.3 2.5 3 0 0 3 3 3 1 Transglutaminase-like superfamily Rad4 PF03835.15 OWF52816.1 - 4.5e-12 45.9 4.1 9.4e-12 44.8 4.1 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain NUDIX PF00293.28 OWF52817.1 - 7.5e-31 106.9 0.0 4.6e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain DDE_Tnp_4 PF13359.6 OWF52818.1 - 2.6e-27 95.4 0.0 3e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OWF52818.1 - 4.3e-05 23.2 0.0 7.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein FA_hydroxylase PF04116.13 OWF52820.1 - 3.9e-20 72.5 24.5 3.9e-20 72.5 24.5 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Glycos_transf_2 PF00535.26 OWF52821.1 - 2.3e-29 102.4 0.0 4.6e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF52821.1 - 1.1e-13 51.6 1.1 1.9e-13 50.8 1.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 OWF52821.1 - 0.0029 17.2 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 OWF52822.1 - 2.6e-26 92.4 0.1 4.7e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF52822.1 - 6.3e-09 36.2 0.1 1.3e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 OWF52822.1 - 9.9e-06 25.6 0.1 1.7e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 OWF52822.1 - 0.0012 18.4 0.1 0.0029 17.2 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Metallothi_Euk2 PF12809.7 OWF52823.1 - 0.38 11.1 10.2 1.9 8.8 1.1 2.3 2 1 0 2 2 2 0 Eukaryotic metallothionein LicD PF04991.13 OWF52824.1 - 6.4e-10 39.6 0.1 7e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 LicD family DUF5565 PF17720.1 OWF52824.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) Neur_chan_LBD PF02931.23 OWF52825.1 - 3.7e-68 229.2 1.1 5.4e-68 228.7 1.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52825.1 - 2.2e-51 175.2 0.4 6.4e-51 173.7 0.0 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region SLC3A2_N PF16028.5 OWF52825.1 - 0.99 9.0 4.5 0.64 9.6 1.2 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Neur_chan_LBD PF02931.23 OWF52826.1 - 3.1e-62 209.9 4.3 4.6e-62 209.3 4.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52826.1 - 1.3e-41 143.2 0.4 1.7e-41 142.8 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Peptidase_U4 PF03419.13 OWF52826.1 - 1.1 8.5 7.7 0.07 12.4 2.4 1.7 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DZF PF07528.14 OWF52827.1 - 1.2e-77 260.9 0.0 1.8e-77 260.3 0.0 1.3 1 0 0 1 1 1 1 DZF domain zf-met PF12874.7 OWF52827.1 - 5.2e-21 74.3 15.2 2.1e-06 27.9 1.4 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF52827.1 - 1.1e-16 60.6 12.1 2.6e-05 24.4 2.1 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF52827.1 - 0.0024 18.2 17.3 0.21 11.9 0.5 3.7 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OWF52827.1 - 0.32 12.0 9.3 8.9 7.5 0.8 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-U1 PF06220.12 OWF52827.1 - 0.92 9.3 15.3 2.3 8.1 1.6 3.5 3 0 0 3 3 3 0 U1 zinc finger zf-C2H2 PF00096.26 OWF52827.1 - 3.3 8.4 15.2 8.9 7.0 0.1 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-DBF PF07535.12 OWF52827.1 - 9.9 6.4 15.9 11 6.3 1.3 3.6 3 0 0 3 3 3 0 DBF zinc finger Ras PF00071.22 OWF52828.1 - 6.1e-36 123.5 0.1 7.4e-36 123.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF52828.1 - 2.8e-11 43.7 0.0 5.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF52828.1 - 0.006 16.1 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF52828.1 - 0.0077 16.1 0.0 3.8 7.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 OWF52828.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OWF52828.1 - 0.19 12.0 0.0 0.56 10.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain SSF PF00474.17 OWF52829.1 - 1.1e-138 462.5 21.1 1.6e-138 462.0 21.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Babuvirus_MP PF07234.11 OWF52829.1 - 0.097 12.8 5.8 5.8 7.1 0.1 3.3 3 0 0 3 3 3 0 Movement and RNA silencing protein Gemini_mov PF01708.16 OWF52829.1 - 0.57 10.0 2.3 11 5.9 0.1 3.4 3 0 0 3 3 3 0 Geminivirus putative movement protein C1q PF00386.21 OWF52830.1 - 4e-16 59.4 0.0 7.4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 C1q domain FemAB PF02388.16 OWF52830.1 - 0.0078 15.1 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 FemAB family Sugarporin_N PF11471.8 OWF52830.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension C1q PF00386.21 OWF52831.1 - 6.3e-20 71.7 0.2 1.2e-19 70.8 0.0 1.5 2 0 0 2 2 2 1 C1q domain SusD-like PF12741.7 OWF52831.1 - 0.13 11.1 1.0 1.7 7.4 0.1 2.0 1 1 0 2 2 2 0 Susd and RagB outer membrane lipoprotein C1q PF00386.21 OWF52832.1 - 4.4e-18 65.7 0.1 7.2e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 C1q domain SHS2_Rpb7-N PF03876.17 OWF52832.1 - 0.084 13.3 0.2 0.23 11.8 0.1 1.7 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 C1q PF00386.21 OWF52833.1 - 9.6e-16 58.1 0.0 1.1e-15 58.0 0.0 1.0 1 0 0 1 1 1 1 C1q domain DNA_gyraseB PF00204.25 OWF52833.1 - 0.09 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA gyrase B C1q PF00386.21 OWF52834.1 - 4.7e-18 65.6 0.3 8e-18 64.9 0.3 1.4 1 0 0 1 1 1 1 C1q domain DUF2913 PF11140.8 OWF52834.1 - 0.049 13.4 0.2 0.071 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Nse5 PF08691.10 OWF52834.1 - 0.055 12.1 0.3 0.072 11.7 0.3 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 C1q PF00386.21 OWF52835.1 - 1.8e-15 57.3 0.3 2.6e-15 56.7 0.3 1.2 1 0 0 1 1 1 1 C1q domain JAKMIP_CC3 PF16034.5 OWF52835.1 - 0.082 12.8 1.0 0.18 11.7 0.5 1.7 2 0 0 2 2 2 0 JAKMIP CC3 domain Barwin PF00967.17 OWF52835.1 - 0.097 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Barwin family Shufflon_N PF04917.12 OWF52836.1 - 0.013 15.0 1.9 0.017 14.6 1.9 1.3 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region DUF1082 PF06449.11 OWF52836.1 - 2 8.3 8.5 25 4.8 1.2 3.5 1 1 2 3 3 3 0 Mitochondrial domain of unknown function (DUF1082) Forkhead PF00250.18 OWF52837.1 - 6.1e-36 122.6 0.5 1.1e-35 121.8 0.5 1.4 1 0 0 1 1 1 1 Forkhead domain Beta-lactamase PF00144.24 OWF52839.1 - 2.5e-45 155.2 0.0 3.6e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 OWF52839.1 - 0.0074 16.7 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Pollen_allerg_1 PF01357.21 OWF52840.1 - 0.066 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Pollen allergen DPBB_1 PF03330.18 OWF52842.1 - 0.021 15.1 0.2 0.1 12.9 0.2 2.1 1 1 0 1 1 1 0 Lytic transglycolase DUF4988 PF16378.5 OWF52842.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function CBM64 PF18666.1 OWF52842.1 - 0.18 11.9 1.2 15 5.7 0.0 3.6 3 1 0 3 3 3 0 Carbohydrate-binding module 64 ASC PF00858.24 OWF52843.1 - 2.1e-101 340.1 7.4 2.6e-101 339.8 7.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Peptidase_M3_N PF08439.10 OWF52843.1 - 1 9.7 3.8 14 6.0 0.0 3.1 3 0 0 3 3 3 0 Oligopeptidase F PC4 PF02229.16 OWF52844.1 - 7.5e-25 86.3 0.1 1.2e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Kisspeptin PF15152.6 OWF52844.1 - 0.077 13.8 0.3 2.9 8.8 0.0 2.3 2 0 0 2 2 2 0 Kisspeptin 4F5 PF04419.14 OWF52845.1 - 5.3e-09 36.8 12.9 6.3e-09 36.6 12.9 1.1 1 0 0 1 1 1 1 4F5 protein family Proteasome PF00227.26 OWF52846.1 - 1.6e-57 194.1 0.1 2e-57 193.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OWF52846.1 - 8.5e-14 50.9 0.1 1.4e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TRP_N PF14558.6 OWF52846.1 - 0.018 15.4 0.2 0.037 14.4 0.1 1.6 2 0 0 2 2 2 0 ML-like domain Collagen PF01391.18 OWF52847.1 - 4.9e-164 532.3 513.2 3e-08 33.3 16.9 23.2 1 1 24 25 25 25 23 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.6 OWF52847.1 - 9.7e-14 51.4 28.4 1.5e-07 31.6 6.0 3.5 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 OWF52847.1 - 2e-12 47.1 30.1 1.3e-05 25.3 7.0 3.3 3 0 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.7 OWF52847.1 - 7e-11 41.8 18.5 1.8e-07 30.9 1.3 3.6 4 0 0 4 4 4 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 OWF52847.1 - 0.24 11.7 11.2 0.015 15.6 4.5 2.3 2 0 0 2 2 2 0 Pvs28 EGF domain Collagen PF01391.18 OWF52848.1 - 0 1152.5 1211.6 7.2e-08 32.1 17.7 52.3 1 1 12 13 13 13 5 Collagen triple helix repeat (20 copies) cEGF PF12662.7 OWF52848.1 - 2.3e-37 126.5 54.2 5.8e-09 35.7 2.0 7.4 7 0 0 7 7 7 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF52848.1 - 2.1e-35 120.7 110.0 9.1e-09 35.4 13.0 7.8 8 0 0 8 8 8 6 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 OWF52848.1 - 3.9e-30 103.8 114.1 1.2e-07 31.8 6.0 8.4 7 1 1 8 8 8 7 Calcium-binding EGF domain EGF_3 PF12947.7 OWF52848.1 - 2e-05 24.7 92.4 0.0097 16.1 9.1 8.1 6 1 1 7 7 7 6 EGF domain hEGF PF12661.7 OWF52848.1 - 0.0054 17.3 1.7 0.0054 17.3 1.7 9.8 9 0 0 9 9 9 3 Human growth factor-like EGF EGF PF00008.27 OWF52848.1 - 6.7 7.1 111.0 0.65 10.3 6.5 9.4 8 0 0 8 8 8 0 EGF-like domain Methyltransf_32 PF13679.6 OWF52849.1 - 3.4e-25 88.9 6.6 7.8e-23 81.2 6.8 2.8 2 1 0 2 2 2 1 Methyltransferase domain Peptidase_S8 PF00082.22 OWF52850.1 - 2.7e-51 174.6 4.8 4.2e-51 174.0 4.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OWF52850.1 - 7.5e-27 93.2 0.0 1.8e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OWF52850.1 - 3.4e-23 82.2 2.7 8.4e-23 80.9 2.7 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like_2 PF15913.5 OWF52850.1 - 0.0048 17.0 7.9 0.0066 16.6 0.2 2.6 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich Ank_2 PF12796.7 OWF52851.1 - 1.2e-55 186.0 9.1 5.5e-16 58.9 0.6 3.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF52851.1 - 5e-28 97.1 0.4 2.9e-09 37.3 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF52851.1 - 2e-26 91.3 0.6 1.2e-06 28.7 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OWF52851.1 - 1.3e-25 89.1 0.2 8.5e-08 32.3 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF52851.1 - 4.4e-23 78.9 0.1 0.0016 18.7 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat BRE1 PF08647.11 OWF52851.1 - 0.0034 17.4 6.7 0.0034 17.4 6.7 8.2 3 1 4 8 8 8 2 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 OWF52851.1 - 0.017 14.0 103.0 0.1 11.4 23.9 5.4 3 1 2 5 5 5 0 Spc7 kinetochore protein Transglut_core PF01841.19 OWF52854.1 - 3.9e-06 27.3 0.0 1.1e-05 25.8 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily ApeC PF16977.5 OWF52856.1 - 1.4e-40 139.4 0.3 5.7e-39 134.2 0.1 2.6 1 1 1 2 2 2 2 C-terminal domain of apextrin Astacin PF01400.24 OWF52856.1 - 3.5e-36 124.6 0.3 6.5e-36 123.7 0.3 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Lectin_C PF00059.21 OWF52856.1 - 4.3e-16 59.6 0.3 1.5e-15 57.8 0.3 2.1 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 OWF52856.1 - 7.7e-13 48.7 0.0 1.6e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 CUB domain Kringle PF00051.18 OWF52856.1 - 3.8e-12 46.3 7.0 1.2e-11 44.7 7.0 1.9 1 0 0 1 1 1 1 Kringle domain UL45 PF05473.12 OWF52856.1 - 1.7e-05 24.6 1.4 0.00014 21.6 1.4 2.2 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Sushi PF00084.20 OWF52856.1 - 0.0021 18.6 0.7 0.029 15.0 0.2 3.0 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) Metallopep PF12044.8 OWF52856.1 - 0.0049 15.5 0.1 0.0079 14.8 0.1 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.6 OWF52856.1 - 0.045 13.7 2.1 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF52856.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 OWF52856.1 - 0.32 11.5 4.8 2.4 8.7 3.9 2.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Usp PF00582.26 OWF52857.1 - 8.3e-27 94.4 0.0 1.4e-26 93.7 0.0 1.3 1 1 0 1 1 1 1 Universal stress protein family NdhM PF10664.9 OWF52857.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M ParD PF09386.10 OWF52858.1 - 0.009 16.4 25.6 21 5.6 0.1 9.7 4 2 8 12 12 12 1 Antitoxin ParD HTH_26 PF13443.6 OWF52858.1 - 1.8 9.1 36.4 84 3.7 0.1 13.6 7 4 6 14 14 14 0 Cro/C1-type HTH DNA-binding domain LuxT_C PF18285.1 OWF52858.1 - 4.2 8.0 15.2 5 7.7 0.1 6.0 3 1 5 8 8 8 0 Tetracycline repressor LuxT C-terminal domain LuxT_C PF18285.1 OWF52859.1 - 0.2 12.2 2.5 11 6.7 0.1 3.0 1 1 2 3 3 3 0 Tetracycline repressor LuxT C-terminal domain HTH_26 PF13443.6 OWF52859.1 - 0.56 10.7 5.0 59 4.2 0.2 3.8 2 2 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain GDNF PF02351.16 OWF52860.1 - 3.4e-07 31.1 25.0 4.6e-05 24.3 10.0 2.4 2 0 0 2 2 2 2 GDNF/GAS1 domain Neur_chan_LBD PF02931.23 OWF52861.1 - 4.5e-45 153.7 0.6 5.8e-45 153.4 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52861.1 - 1.1e-25 91.1 2.2 1.6e-25 90.6 2.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF52862.1 - 7.2e-43 146.5 0.1 9.5e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF52862.1 - 1.2e-32 113.9 3.0 8.9e-29 101.2 2.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region SNF PF00209.18 OWF52864.1 - 2.1e-219 729.6 34.0 4.8e-219 728.4 34.0 1.5 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family zf-H2C2_2 PF13465.6 OWF52865.1 - 1.3e-28 98.1 66.6 8e-08 32.4 1.7 10.1 11 0 0 11 11 10 7 Zinc-finger double domain zf-C2H2 PF00096.26 OWF52865.1 - 9.5e-24 82.5 68.9 3e-05 24.2 0.6 9.7 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF52865.1 - 6.1e-23 79.5 67.7 0.0024 18.6 0.7 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 OWF52865.1 - 1.2e-14 54.1 57.5 0.062 13.7 0.2 9.7 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF52865.1 - 7.9e-13 48.1 64.1 0.00074 19.5 1.2 9.0 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF52865.1 - 6.4e-09 35.9 53.5 0.038 14.3 0.9 9.4 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OWF52865.1 - 0.00016 21.9 5.4 0.00016 21.9 5.4 5.8 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OWF52865.1 - 0.0015 18.3 49.5 0.01 15.6 3.6 7.8 8 0 0 8 8 8 4 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OWF52865.1 - 0.015 15.2 27.2 4.7 7.2 0.1 7.2 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 OWF52865.1 - 0.31 10.9 0.0 0.31 10.9 0.0 4.7 5 0 0 5 5 4 0 Rad50 zinc hook motif BolA PF01722.18 OWF52865.1 - 1.1 9.6 9.6 15 6.0 1.3 4.2 3 2 1 4 4 4 0 BolA-like protein ADK_lid PF05191.14 OWF52865.1 - 1.5 8.9 17.6 19 5.3 0.6 6.2 3 1 3 6 6 6 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 OWF52865.1 - 1.7 8.8 40.2 0.94 9.7 1.9 6.5 4 1 2 6 6 6 0 Zinc ribbon domain zf-C2H2 PF00096.26 OWF52866.1 - 5.3e-29 99.0 60.9 0.00016 21.9 1.3 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF52866.1 - 3.7e-24 83.3 57.8 0.0077 17.0 0.2 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF52866.1 - 6.1e-22 77.0 48.4 3.3e-07 30.4 0.1 9.1 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF52866.1 - 1e-12 47.7 55.0 8.7e-05 22.4 1.2 9.0 9 0 0 9 9 8 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF52866.1 - 2.7e-07 30.2 41.9 0.0026 17.5 0.6 7.1 7 0 0 7 7 7 5 zinc-finger C2H2-type zf-met PF12874.7 OWF52866.1 - 5.9e-05 23.3 44.3 0.012 16.0 1.8 8.8 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF52866.1 - 0.0014 18.9 42.9 0.013 15.8 3.7 8.2 9 0 0 9 9 8 2 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 OWF52866.1 - 0.011 15.3 1.0 0.011 15.3 1.0 5.7 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn-ribbon_8 PF09723.10 OWF52866.1 - 0.033 14.3 0.7 0.033 14.3 0.7 6.9 3 2 4 7 7 7 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 OWF52866.1 - 0.04 13.8 32.0 0.098 12.6 4.6 4.8 4 0 0 4 4 4 0 SprT-like zinc ribbon domain FYVE PF01363.21 OWF52866.1 - 0.77 9.9 35.7 0.53 10.5 8.1 5.1 2 2 2 4 4 4 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 OWF52866.1 - 1.4 9.7 25.7 4.2 8.2 0.3 5.0 2 1 2 4 4 4 0 zinc-ribbon family BolA PF01722.18 OWF52866.1 - 1.8 8.9 8.3 18 5.7 0.2 3.6 2 1 1 3 3 3 0 BolA-like protein zf-C2H2_8 PF15909.5 OWF52866.1 - 7.6 6.9 29.3 1.3 9.3 7.6 4.2 2 2 2 4 4 4 0 C2H2-type zinc ribbon Peptidase_C2 PF00648.21 OWF52867.1 - 2.4e-81 273.0 0.0 3.9e-81 272.3 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.18 OWF52867.1 - 5.9e-23 79.9 80.4 5.2e-06 25.7 3.2 7.5 7 0 0 7 7 7 7 Zn-finger in Ran binding protein and others DZR PF12773.7 OWF52867.1 - 0.11 12.5 56.4 0.022 14.8 10.9 6.2 5 1 0 5 5 5 0 Double zinc ribbon PH PF00169.29 OWF52868.1 - 7.3e-18 65.0 0.3 1.9e-17 63.7 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF52868.1 - 0.0012 19.2 0.3 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 OWF52868.1 - 0.18 12.1 0.0 0.43 10.9 0.0 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Myotub-related PF06602.14 OWF52869.1 - 3.7e-142 473.4 0.0 4.8e-142 473.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 OWF52869.1 - 2.5e-10 40.4 11.3 6e-10 39.1 11.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger DSPc PF00782.20 OWF52869.1 - 0.0064 16.3 0.1 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Vps36_ESCRT-II PF11605.8 OWF52869.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase PF00102.27 OWF52869.1 - 0.039 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF52869.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family SKA1 PF07160.12 OWF52869.1 - 0.072 12.9 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 KASH_CCD PF14662.6 OWF52870.1 - 6.8e-06 26.0 6.7 6.8e-06 26.0 6.7 8.6 3 2 4 8 8 8 2 Coiled-coil region of CCDC155 or KASH Takusan PF04822.13 OWF52870.1 - 0.00019 21.2 1.7 0.00019 21.2 1.7 9.5 8 3 2 10 10 10 1 Takusan CEP63 PF17045.5 OWF52870.1 - 0.00096 19.1 16.5 0.00096 19.1 16.5 7.5 3 2 5 8 8 8 2 Centrosomal protein of 63 kDa DUF3450 PF11932.8 OWF52870.1 - 0.0024 17.2 12.7 0.0024 17.2 12.7 12.5 3 2 8 12 12 12 4 Protein of unknown function (DUF3450) DUF3663 PF12404.8 OWF52870.1 - 0.15 12.1 0.1 0.58 10.2 0.1 2.0 1 0 0 1 1 1 0 Peptidase TP2 PF01254.18 OWF52870.1 - 8.1 7.1 15.7 12 6.5 6.2 3.3 2 0 0 2 2 2 0 Nuclear transition protein 2 FAST_2 PF08368.12 OWF52871.1 - 2.9e-09 37.6 0.1 3e-08 34.3 0.0 2.8 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 OWF52871.1 - 0.00086 19.2 1.9 0.081 12.9 0.1 3.4 2 1 0 2 2 2 2 FAST kinase-like protein, subdomain 1 FragX_IP PF05994.11 OWF52872.1 - 0 1340.4 2.6 0 1339.8 2.6 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 OWF52872.1 - 2e-10 40.4 5.2 4.8e-10 39.2 5.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) BP28CT PF08146.12 OWF52872.1 - 0.035 14.0 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 BP28CT (NUC211) domain TbpB_A PF17484.2 OWF52872.1 - 0.04 14.7 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B SSF PF00474.17 OWF52874.1 - 5.5e-44 150.7 23.6 6.8e-44 150.3 23.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family HALZ PF02183.18 OWF52875.1 - 7.4e-05 22.9 5.7 1.1 9.5 0.3 4.1 3 0 0 3 3 3 3 Homeobox associated leucine zipper HTH_19 PF12844.7 OWF52875.1 - 0.097 12.7 1.4 0.26 11.3 0.5 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_C_13 PF16925.5 OWF52875.1 - 2.4 8.1 4.8 2.9 7.9 0.2 3.0 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain ADIP PF11559.8 OWF52875.1 - 2.5 8.2 38.6 0.05 13.7 5.1 4.2 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 OWF52875.1 - 7.6 6.3 40.0 0.12 12.2 6.5 3.6 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF3591 PF12157.8 OWF52876.1 - 1.8e-158 527.9 2.9 5.7e-158 526.2 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 OWF52876.1 - 4.3e-36 122.8 2.2 1.2e-17 63.7 0.2 2.8 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.11 OWF52876.1 - 2e-20 72.8 2.5 6.5e-20 71.1 2.5 1.9 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 OWF52876.1 - 2.3e-12 46.5 0.9 6.5e-12 45.1 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle Pet127 PF08634.10 OWF52876.1 - 7.7 5.9 8.6 0.71 9.3 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial protein Pet127 WD40 PF00400.32 OWF52877.1 - 5.1e-31 106.2 31.2 1.3e-05 25.8 0.3 11.0 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF52877.1 - 3.8e-19 68.8 3.2 0.0044 17.3 0.1 7.0 4 3 3 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF52877.1 - 3.1e-07 29.4 9.6 0.065 11.9 0.0 5.7 6 0 0 6 6 6 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 OWF52877.1 - 0.017 15.2 0.0 8.7 6.4 0.0 4.8 6 1 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 OWF52877.1 - 0.03 13.3 0.3 2 7.3 0.0 3.6 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GEMIN8 PF15348.6 OWF52878.1 - 4.5e-46 158.0 0.5 4.5e-46 158.0 0.5 1.9 2 0 0 2 2 2 1 Gemini of Cajal bodies-associated protein 8 FXMRP1_C_core PF12235.8 OWF52878.1 - 0.19 12.4 14.0 0.77 10.4 14.0 2.1 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal PDZ PF00595.24 OWF52879.1 - 5.3e-16 58.8 0.5 1.7e-15 57.1 0.2 2.1 2 0 0 2 2 2 1 PDZ domain WW PF00397.26 OWF52879.1 - 6.6e-12 45.3 1.1 1.1e-11 44.6 1.1 1.4 1 0 0 1 1 1 1 WW domain PDZ_6 PF17820.1 OWF52879.1 - 2.1e-08 33.9 0.6 5.7e-08 32.5 0.1 2.1 3 0 0 3 3 3 1 PDZ domain zf-C4H2 PF10146.9 OWF52879.1 - 0.87 9.9 7.6 0.33 11.2 4.5 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein HALZ PF02183.18 OWF52879.1 - 1.7 8.9 5.6 0.41 10.9 1.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 OWF52879.1 - 2.7 8.1 18.7 0.44 10.6 4.1 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF883 PF05957.13 OWF52879.1 - 3.4 8.3 6.8 2.6 8.7 4.4 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HisKA_3 PF07730.13 OWF52879.1 - 9 6.9 7.6 5.1 7.7 0.3 3.6 3 1 1 4 4 4 0 Histidine kinase Rad60-SLD_2 PF13881.6 OWF52880.1 - 9.5e-29 99.7 0.0 1.1e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OWF52880.1 - 0.00048 19.8 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 OWF52880.1 - 0.16 12.5 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF4606 PF15379.6 OWF52881.1 - 4.4e-20 71.9 0.2 4.4e-20 71.9 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4606) HECT PF00632.25 OWF52883.1 - 4.2e-91 305.6 0.3 4.2e-91 305.6 0.3 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OWF52883.1 - 5.1e-16 58.7 2.7 1e-15 57.7 2.7 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-NF-X1 PF01422.17 OWF52884.1 - 7e-10 38.8 263.5 4.5e-05 23.4 18.6 16.2 17 0 0 17 17 17 10 NF-X1 type zinc finger cNMP_binding PF00027.29 OWF52885.1 - 2.7e-16 59.4 0.0 2.2e-10 40.4 0.0 3.3 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain AdHead_fibreRBD PF16812.5 OWF52885.1 - 0.083 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 C-terminal head domain of the fowl adenovirus type 1 long fibre DUF5528 PF17666.1 OWF52885.1 - 8 6.4 10.1 0.97 9.4 0.2 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5528) OxoDH_E1alpha_N PF12573.8 OWF52886.1 - 0.088 12.6 11.2 51 3.7 0.0 6.5 4 2 4 9 9 9 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal GreA_GreB PF01272.19 OWF52886.1 - 0.11 12.4 4.3 1.1e+02 2.8 0.0 6.1 8 0 0 8 8 8 0 Transcription elongation factor, GreA/GreB, C-term MOZART1 PF12554.8 OWF52887.1 - 0.00039 20.2 7.6 9.7 6.1 0.0 6.2 9 0 0 9 9 9 3 Mitotic-spindle organizing gamma-tubulin ring associated TetM_leader PF08076.11 OWF52887.1 - 0.0099 15.6 23.1 0.55 10.1 0.1 6.6 8 0 0 8 8 8 3 Tetracycline resistance determinant leader peptide OxoDH_E1alpha_N PF12573.8 OWF52887.1 - 0.024 14.4 7.2 3.1 7.6 0.1 4.2 2 1 2 5 5 5 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal FLgD_tudor PF13861.6 OWF52887.1 - 0.95 9.8 6.7 2e+02 2.3 0.0 5.9 8 1 1 9 9 9 0 FlgD Tudor-like domain WD40 PF00400.32 OWF52888.1 - 1.5e-36 123.7 19.7 5.5e-09 36.5 0.2 12.3 13 0 0 13 13 12 5 WD domain, G-beta repeat Utp12 PF04003.12 OWF52888.1 - 4.1e-24 84.9 0.1 7.3e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OWF52888.1 - 8e-23 80.6 0.0 0.064 13.6 0.0 9.2 4 3 5 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF52888.1 - 1.8e-08 33.7 0.5 0.7 8.8 0.0 6.2 5 3 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OWF52888.1 - 1.8e-07 30.9 0.0 0.91 9.5 0.0 4.9 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OWF52888.1 - 6.5e-07 29.4 0.6 0.025 14.5 0.1 4.6 3 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.6 OWF52888.1 - 0.0066 16.7 0.0 1.7 9.0 0.0 3.1 2 0 0 2 2 2 1 Kelch motif WD40_like PF17005.5 OWF52888.1 - 0.016 14.5 0.1 0.33 10.2 0.0 2.9 3 1 0 3 3 3 0 WD40-like domain Sigma70_r3 PF04539.16 OWF52888.1 - 0.047 13.8 0.1 0.047 13.8 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 Nbas_N PF15492.6 OWF52888.1 - 0.064 12.6 0.0 5.9 6.1 0.0 3.6 3 3 3 6 6 6 0 Neuroblastoma-amplified sequence, N terminal PBP1_TM PF14812.6 OWF52888.1 - 2.1 8.8 8.7 6.3 7.3 0.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_C PF00137.21 OWF52889.1 - 1.3e-36 124.7 37.4 1.9e-22 79.4 14.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PIRT PF15099.6 OWF52889.1 - 0.24 11.0 0.7 0.43 10.2 0.7 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family HSP90 PF00183.18 OWF52890.1 - 6.2e-105 352.0 6.9 8.2e-102 341.7 3.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 OWF52890.1 - 4.7e-11 42.7 0.1 1.1e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OWF52890.1 - 7.1e-08 33.0 0.1 1.4e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBM46 PF18448.1 OWF52891.1 - 8.2e-08 32.5 75.6 1.4e+02 2.9 0.3 23.7 1 1 35 38 38 38 6 Carbohydrate binding domain Ins_beta PF03488.14 OWF52892.1 - 6e-09 35.8 27.3 2.1 8.4 0.2 11.1 5 4 4 9 9 9 3 Nematode insulin-related peptide beta type DUF2963 PF11178.8 OWF52892.1 - 1.2e-05 24.9 18.3 4.1 7.2 0.1 8.2 4 3 4 8 8 8 3 Protein of unknown function (DUF2963) TM140 PF14985.6 OWF52892.1 - 0.00092 18.8 6.6 1.6 8.3 0.0 5.3 2 2 5 7 7 7 1 TM140 protein family Insulin PF00049.18 OWF52892.1 - 0.0013 19.7 29.7 21 6.2 0.4 8.9 3 3 5 8 8 8 0 Insulin/IGF/Relaxin family Ribosomal_L12_N PF16320.5 OWF52892.1 - 0.012 15.3 0.6 42 4.0 0.0 5.4 3 1 2 5 5 5 0 Ribosomal protein L7/L12 dimerisation domain YqgC PF17430.2 OWF52892.1 - 0.036 14.1 18.4 89 3.3 0.0 11.1 5 5 11 16 16 16 0 Uncharacterized YqgC-like P22_Cro PF14549.6 OWF52892.1 - 0.036 13.9 3.4 16 5.5 0.1 6.3 4 2 2 7 7 7 0 DNA-binding transcriptional regulator Cro PorA PF11271.8 OWF52892.1 - 0.15 11.3 0.9 25 4.0 0.0 3.6 3 1 0 3 3 3 0 Porin PorA DUF211 PF02680.14 OWF52892.1 - 0.4 10.9 15.6 7.3 6.8 0.1 5.7 1 1 4 6 6 6 0 Uncharacterized ArCR, COG1888 MamL-1 PF09596.10 OWF52893.1 - 9e-21 73.9 5.8 9e-21 73.9 5.8 4.8 4 0 0 4 4 4 1 MamL-1 domain AMOP PF03782.17 OWF52894.1 - 1.3e-47 161.6 6.1 2.3e-47 160.7 6.1 1.4 1 0 0 1 1 1 1 AMOP domain VWD PF00094.25 OWF52894.1 - 5.5e-12 46.2 0.3 1.4e-11 44.9 0.3 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain NIDO PF06119.14 OWF52894.1 - 0.00011 23.1 0.4 0.00011 23.1 0.4 3.4 4 0 0 4 4 3 1 Nidogen-like EphA2_TM PF14575.6 OWF52894.1 - 0.0025 18.7 0.0 0.005 17.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OWF52894.1 - 0.0042 16.9 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 OWF52894.1 - 0.026 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 OWF52894.1 - 0.044 13.7 0.1 0.096 12.6 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 OWF52894.1 - 0.046 13.6 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 OWF52894.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless DAG1 PF05454.11 OWF52894.1 - 0.19 11.0 0.1 0.36 10.2 0.1 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF3827 PF12877.7 OWF52894.1 - 0.27 9.5 1.2 0.41 9.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SLAIN PF15301.6 OWF52895.1 - 1.4e-21 77.2 36.7 2.9e-14 53.2 21.8 3.7 1 1 2 3 3 3 2 SLAIN motif-containing family MAP70 PF07058.11 OWF52895.1 - 0.11 11.2 2.5 0.22 10.2 2.5 1.4 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF1720 PF08226.11 OWF52895.1 - 1.4 9.4 6.9 0.46 10.9 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) AC_N PF16214.5 OWF52895.1 - 9.3 5.3 6.1 14 4.6 6.1 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TPR_1 PF00515.28 OWF52896.1 - 3.8e-18 64.5 0.9 1.5e-07 30.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat HipN PF18253.1 OWF52896.1 - 3.1e-15 55.6 0.1 1.1e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain TPR_2 PF07719.17 OWF52896.1 - 7.6e-15 53.8 4.2 9.1e-05 22.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF52896.1 - 2.4e-10 39.9 0.2 0.0012 18.5 0.0 3.1 2 1 1 3 3 3 3 TPR repeat STI1 PF17830.1 OWF52896.1 - 5.3e-10 39.1 3.6 6.5e-10 38.8 0.3 2.6 2 1 1 3 3 3 1 STI1 domain TPR_8 PF13181.6 OWF52896.1 - 6.9e-09 35.2 10.2 4e-05 23.5 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF52896.1 - 1.5e-08 34.4 0.2 0.00029 21.0 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF52896.1 - 1.3e-05 25.7 0.0 0.18 12.5 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF52896.1 - 0.00013 22.4 0.0 0.0071 16.8 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF52896.1 - 0.002 18.3 0.0 0.025 14.7 0.0 2.4 2 1 1 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF52896.1 - 0.0036 17.5 0.4 0.021 15.0 0.1 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OWF52896.1 - 0.0055 17.4 0.1 5.2 8.2 0.0 3.7 2 1 2 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.8 OWF52896.1 - 0.0088 15.0 0.7 0.0088 15.0 0.7 2.4 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 OWF52896.1 - 0.017 15.4 0.0 1.1 9.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF52896.1 - 0.062 14.0 2.2 28 5.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 OWF52896.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 OWF52896.1 - 0.12 11.7 0.0 1 8.7 0.0 2.0 1 1 0 1 1 1 0 MalT-like TPR region Sporozoite_P67 PF05642.11 OWF52896.1 - 0.63 8.1 10.5 0.97 7.4 10.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CD99L2 PF12301.8 OWF52896.1 - 3.3 8.0 11.1 0.39 11.0 6.1 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 RhoGEF67_u2 PF16614.5 OWF52896.1 - 5.8 7.0 6.4 2.6 8.2 2.6 2.3 3 0 0 3 3 3 0 Unstructured region two on RhoGEF 6 and 7 Peptidase_M24 PF00557.24 OWF52897.1 - 9.4e-53 179.0 0.0 1.3e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OWF52897.1 - 1.5e-31 108.6 0.0 2.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GATase_6 PF13522.6 OWF52898.1 - 2.4e-16 60.2 0.0 4.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OWF52898.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OWF52898.1 - 2.8e-08 33.4 0.1 5.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 OWF52898.1 - 9e-05 21.5 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 OWF52898.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase SAICAR_synt PF01259.18 OWF52899.1 - 2.3e-52 178.1 0.0 3.1e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 OWF52899.1 - 5.6e-38 129.8 0.0 8.7e-38 129.2 0.0 1.3 1 0 0 1 1 1 1 AIR carboxylase Pkinase PF00069.25 OWF52900.1 - 2e-76 256.9 0.0 3e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.17 OWF52900.1 - 4.6e-40 135.5 0.3 2.7e-19 69.0 0.1 2.6 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.17 OWF52900.1 - 1.3e-36 126.2 0.0 1.9e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF52900.1 - 0.00081 18.8 0.0 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OWF52900.1 - 0.011 14.5 0.0 0.024 13.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OWF52900.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family P33MONOX PF15302.6 OWF52900.1 - 0.098 12.4 2.2 0.16 11.6 2.2 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase RIO1 PF01163.22 OWF52900.1 - 0.098 12.2 1.2 0.54 9.8 1.0 2.1 1 1 1 2 2 2 0 RIO1 family TMCCDC2 PF15844.5 OWF52900.1 - 0.16 11.9 0.1 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 DUF4801 PF16059.5 OWF52901.1 - 5.3e-09 35.9 10.8 5.3e-09 35.9 10.8 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4801) HLH PF00010.26 OWF52901.1 - 1.5e-05 24.8 0.2 8.1e-05 22.5 0.2 2.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MIEAP PF16026.5 OWF52902.1 - 6.1e-40 137.6 1.5 6.1e-40 137.6 1.5 2.4 3 0 0 3 3 3 1 Mitochondria-eating protein Leu_zip PF15294.6 OWF52902.1 - 0.00083 19.0 14.7 0.0031 17.1 14.8 1.9 1 1 0 1 1 1 1 Leucine zipper TSC22 PF01166.18 OWF52902.1 - 0.0073 16.6 10.5 8.4 6.8 0.2 4.7 4 0 0 4 4 4 2 TSC-22/dip/bun family NepR PF18557.1 OWF52902.1 - 0.075 12.7 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 Anti-sigma factor NepR GAS PF13851.6 OWF52902.1 - 0.26 10.6 21.4 0.32 10.3 3.5 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 OWF52902.1 - 0.98 9.5 15.9 0.39 10.8 5.8 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 OWF52902.1 - 1 9.1 10.8 0.16 11.7 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Cluap1 PF10234.9 OWF52902.1 - 1.1 8.6 14.1 3.7 6.9 14.1 2.0 1 1 0 1 1 1 0 Clusterin-associated protein-1 Herpes_BLRF2 PF05812.12 OWF52902.1 - 2 8.6 10.9 2.7 8.2 0.2 3.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Cnn_1N PF07989.11 OWF52902.1 - 6.8 6.9 11.7 6.8 6.9 3.1 3.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 THOC7 PF05615.13 OWF52902.1 - 8.6 6.7 12.5 0.52 10.6 6.5 2.2 2 0 0 2 2 1 0 Tho complex subunit 7 HSP70 PF00012.20 OWF52903.1 - 0.17 10.0 0.0 1 7.5 0.0 2.1 1 1 0 1 1 1 0 Hsp70 protein Thymosin PF01290.20 OWF52904.1 - 1.8e-53 178.0 51.2 2.4e-10 40.0 2.9 8.1 8 0 0 8 8 8 8 Thymosin beta-4 family Kdo PF06293.14 OWF52904.1 - 0.0069 15.8 0.2 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family IRF-3 PF10401.9 OWF52904.1 - 2.1 8.1 6.7 11 5.7 0.1 4.1 1 1 2 4 4 4 0 Interferon-regulatory factor 3 Glyco_transf_41 PF13844.6 OWF52906.1 - 4.8e-227 754.0 0.0 6.7e-227 753.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 OWF52906.1 - 2.8e-94 305.4 32.5 6.2e-09 35.3 0.1 13.0 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 OWF52906.1 - 2.9e-89 292.5 41.4 8.9e-12 44.5 1.3 12.9 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 OWF52906.1 - 2.7e-72 233.2 28.4 8.7e-07 28.6 0.4 13.1 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 OWF52906.1 - 4.6e-68 220.8 32.5 2.5e-07 30.6 0.1 13.3 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_8 PF13181.6 OWF52906.1 - 1.7e-63 205.6 20.6 1.5e-05 24.8 0.1 13.6 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_12 PF13424.6 OWF52906.1 - 7.2e-48 160.8 29.1 2.9e-11 43.5 1.5 9.6 5 2 6 11 11 11 9 Tetratricopeptide repeat TPR_14 PF13428.6 OWF52906.1 - 2.7e-42 139.8 11.5 0.0003 21.4 0.0 12.4 5 3 7 12 12 12 9 Tetratricopeptide repeat TPR_7 PF13176.6 OWF52906.1 - 4.4e-40 132.8 18.8 0.00034 20.4 0.0 12.6 13 1 1 14 14 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 OWF52906.1 - 8.7e-39 131.9 16.4 3e-07 31.0 0.0 8.0 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.6 OWF52906.1 - 9.9e-39 131.7 22.0 4.8e-06 27.0 0.1 9.0 2 2 7 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 OWF52906.1 - 1.7e-36 123.1 44.8 5.6e-06 26.0 0.8 12.3 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_9 PF13371.6 OWF52906.1 - 4.4e-18 65.2 6.1 0.0044 17.1 0.1 6.6 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 OWF52906.1 - 3.5e-15 55.5 16.0 0.53 11.0 0.0 10.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 OWF52906.1 - 1.2e-14 53.3 1.4 0.12 13.0 0.0 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat NARP1 PF12569.8 OWF52906.1 - 3.9e-14 52.5 6.8 0.001 18.1 0.1 5.6 1 1 5 6 6 6 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 OWF52906.1 - 1.9e-12 47.2 11.2 0.00016 21.2 0.2 4.5 2 2 1 4 4 4 4 MalT-like TPR region TPR_15 PF13429.6 OWF52906.1 - 6.5e-09 35.4 8.7 0.00026 20.3 0.2 4.7 1 1 2 3 3 3 2 Tetratricopeptide repeat FAT PF02259.23 OWF52906.1 - 8.7e-09 35.0 0.7 0.37 9.9 0.0 5.9 2 2 3 5 5 5 1 FAT domain TPR_21 PF09976.9 OWF52906.1 - 6.3e-07 29.3 12.4 0.11 12.2 0.4 5.2 3 2 1 4 4 4 3 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 OWF52906.1 - 3.7e-06 27.0 5.9 0.074 13.0 0.1 4.1 4 0 0 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal EST1_DNA_bind PF10373.9 OWF52906.1 - 4.2e-05 23.2 11.6 0.48 9.9 0.1 4.7 3 1 2 5 5 5 3 Est1 DNA/RNA binding domain MIT PF04212.18 OWF52906.1 - 4.6e-05 23.4 27.2 4.6 7.4 0.1 8.7 9 0 0 9 9 8 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 OWF52906.1 - 0.00038 20.9 12.1 1.3 9.5 0.5 5.2 2 2 4 6 6 6 1 Bacterial transcriptional activator domain SNAP PF14938.6 OWF52906.1 - 0.00047 19.7 17.1 0.11 11.9 3.7 5.1 1 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 OWF52906.1 - 0.00096 19.1 7.0 0.65 10.1 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF52906.1 - 0.0037 17.5 19.2 0.019 15.2 1.4 5.0 3 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 OWF52906.1 - 0.0063 16.7 2.4 59 4.2 0.0 6.7 8 0 0 8 8 7 0 PPR repeat Fis1_TPR_C PF14853.6 OWF52906.1 - 0.017 15.2 0.2 0.16 12.1 0.0 2.8 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 OWF52906.1 - 0.021 14.3 9.6 3.3 7.2 0.0 6.5 9 1 1 10 10 8 0 SHNi-TPR RPN7 PF10602.9 OWF52906.1 - 0.033 13.9 8.5 10 5.8 0.4 5.7 2 2 5 7 7 7 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 OWF52906.1 - 0.052 13.9 16.3 0.38 11.1 0.4 6.6 4 2 3 8 8 8 0 Tetratricopeptide repeat Tcf25 PF04910.14 OWF52906.1 - 0.098 11.7 0.4 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 Transcriptional repressor TCF25 TOM20_plant PF06552.12 OWF52906.1 - 0.14 11.9 0.8 31 4.2 0.0 4.0 1 1 2 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Coatomer_E PF04733.14 OWF52906.1 - 0.15 11.5 1.3 4.8 6.5 0.5 3.4 2 1 1 4 4 4 0 Coatomer epsilon subunit Mad3_BUB1_I PF08311.12 OWF52906.1 - 0.17 11.9 10.5 68 3.5 0.0 6.5 6 1 1 7 7 7 0 Mad3/BUB1 homology region 1 Alkyl_sulf_dimr PF14863.6 OWF52906.1 - 0.32 11.5 2.5 13 6.3 0.1 3.4 2 1 1 3 3 2 0 Alkyl sulfatase dimerisation DUF627 PF04781.12 OWF52906.1 - 0.73 9.9 5.4 16 5.6 0.0 4.8 2 1 2 4 4 4 0 Protein of unknown function (DUF627) Glyco_transf_41 PF13844.6 OWF52907.1 - 5e-228 757.2 0.0 6.9e-228 756.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 OWF52907.1 - 6.4e-94 304.3 35.3 5e-09 35.6 0.3 13.0 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 OWF52907.1 - 1.4e-87 287.1 40.6 7.2e-12 44.8 1.3 12.9 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 OWF52907.1 - 5.8e-72 232.1 30.9 2.9e-07 30.1 0.2 12.9 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 OWF52907.1 - 3.1e-66 215.1 36.5 2e-07 30.9 0.3 13.5 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 OWF52907.1 - 3.3e-64 207.8 24.2 1.1e-06 28.3 0.1 13.5 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 OWF52907.1 - 7.8e-46 154.3 33.0 1.3e-10 41.4 1.4 9.3 5 3 5 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 OWF52907.1 - 1.6e-41 137.4 14.6 0.0003 21.4 0.0 12.4 5 3 7 12 12 12 9 Tetratricopeptide repeat TPR_16 PF13432.6 OWF52907.1 - 1.1e-38 131.6 17.1 6.5e-08 33.1 0.0 7.5 5 2 1 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 OWF52907.1 - 1.6e-38 131.0 26.4 1.2e-07 32.1 1.1 9.0 5 2 5 10 10 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 OWF52907.1 - 7.9e-38 125.7 19.0 0.00012 21.8 0.1 12.5 13 1 1 14 14 11 9 Tetratricopeptide repeat TPR_10 PF13374.6 OWF52907.1 - 1.9e-34 116.6 47.7 3.6e-06 26.7 1.1 12.4 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_9 PF13371.6 OWF52907.1 - 1e-18 67.3 7.1 0.0063 16.6 0.1 6.4 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 OWF52907.1 - 1.9e-15 56.4 18.9 0.38 11.5 0.0 10.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF52907.1 - 1.8e-12 47.3 11.4 0.00012 21.6 0.2 3.9 1 1 1 3 3 3 3 MalT-like TPR region TPR_4 PF07721.14 OWF52907.1 - 2.4e-11 43.1 6.1 1.5 9.7 0.1 8.3 9 0 0 9 9 7 3 Tetratricopeptide repeat NARP1 PF12569.8 OWF52907.1 - 4e-11 42.5 9.4 0.012 14.6 0.0 5.6 1 1 4 6 6 6 3 NMDA receptor-regulated protein 1 FAT PF02259.23 OWF52907.1 - 4.7e-08 32.6 2.1 0.13 11.5 0.7 5.7 2 2 1 3 3 3 2 FAT domain TPR_15 PF13429.6 OWF52907.1 - 1.4e-07 31.0 13.3 0.00055 19.2 0.3 4.9 1 1 4 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 OWF52907.1 - 5.4e-06 26.2 14.1 0.14 11.8 0.5 5.3 2 1 1 4 4 4 3 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 OWF52907.1 - 1.5e-05 25.0 8.6 0.12 12.3 0.4 4.3 3 1 0 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal EST1_DNA_bind PF10373.9 OWF52907.1 - 2e-05 24.2 14.5 0.1 12.1 0.2 5.1 5 1 1 6 6 6 2 Est1 DNA/RNA binding domain BTAD PF03704.17 OWF52907.1 - 0.00039 20.9 11.0 1.4 9.4 0.1 4.6 2 1 2 4 4 4 2 Bacterial transcriptional activator domain MIT PF04212.18 OWF52907.1 - 0.0038 17.2 28.1 8.1 6.6 0.1 8.6 9 0 0 9 9 8 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 OWF52907.1 - 0.0053 16.2 20.0 0.43 10.0 0.7 4.8 1 1 2 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 OWF52907.1 - 0.0055 16.7 8.1 0.37 10.8 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF52907.1 - 0.015 15.3 0.2 0.16 12.1 0.0 2.9 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat Tcf25 PF04910.14 OWF52907.1 - 0.025 13.6 0.2 0.35 9.9 0.0 2.2 1 1 0 2 2 2 0 Transcriptional repressor TCF25 DUF627 PF04781.12 OWF52907.1 - 0.058 13.4 7.5 29 4.7 0.0 5.1 2 1 2 4 4 4 0 Protein of unknown function (DUF627) ANAPC3 PF12895.7 OWF52907.1 - 0.083 13.1 23.6 0.074 13.3 2.8 5.1 3 2 2 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 OWF52907.1 - 0.088 12.5 7.6 4 7.1 0.1 5.2 2 2 2 5 5 5 0 26S proteasome subunit RPN7 CUE PF02845.16 OWF52907.1 - 0.1 12.3 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 1 0 CUE domain SHNi-TPR PF10516.9 OWF52907.1 - 0.11 11.9 7.4 22 4.6 0.0 5.9 8 0 0 8 8 7 0 SHNi-TPR TPR_20 PF14561.6 OWF52907.1 - 0.17 12.3 16.1 0.38 11.1 0.3 6.0 4 1 3 7 7 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OWF52907.1 - 0.26 11.7 5.4 2.2 8.7 0.0 3.4 3 1 0 3 3 2 0 Alkyl sulfatase dimerisation Mad3_BUB1_I PF08311.12 OWF52907.1 - 0.29 11.1 12.8 34 4.4 0.0 6.6 6 1 1 7 7 7 0 Mad3/BUB1 homology region 1 TOM20_plant PF06552.12 OWF52907.1 - 0.35 10.6 1.6 42 3.8 0.0 4.1 2 1 3 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Aa_trans PF01490.18 OWF52908.1 - 7.1e-79 265.4 18.3 9.8e-79 264.9 18.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ASD2 PF08687.11 OWF52909.1 - 2.5e-55 188.1 14.9 2.5e-55 188.1 14.9 2.6 3 0 0 3 3 3 1 Apx/Shroom domain ASD2 Lipoprotein_16 PF03923.13 OWF52909.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized lipoprotein p450 PF00067.22 OWF52910.1 - 5.5e-116 388.0 0.0 6.3e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF52911.1 - 8.7e-43 146.7 0.0 9.5e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF52912.1 - 1.7e-120 402.9 0.0 1.9e-120 402.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mrpl_C PF18502.1 OWF52912.1 - 0.12 12.7 1.0 5.3 7.4 0.0 2.3 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain p450 PF00067.22 OWF52913.1 - 1.1e-117 393.6 0.0 1.3e-117 393.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1180 PF06679.12 OWF52914.1 - 0.44 10.9 1.3 0.72 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4131 PF13567.6 OWF52914.1 - 0.72 9.5 21.9 1.4 8.6 0.0 4.8 3 1 2 6 6 6 0 Domain of unknown function (DUF4131) LRR_8 PF13855.6 OWF52915.1 - 3.2e-63 209.4 122.2 1e-14 54.0 7.1 9.5 2 1 9 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 OWF52915.1 - 2.4e-31 107.3 80.5 4.6e-06 26.9 1.3 11.4 8 2 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF52915.1 - 2e-26 92.4 10.8 2.9e-11 43.4 0.1 5.4 2 2 3 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF52915.1 - 6.5e-14 51.8 34.7 0.00034 20.2 3.2 6.1 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 OWF52915.1 - 1.3e-05 25.1 54.1 0.12 12.9 0.2 14.2 13 3 0 13 13 12 3 Leucine Rich Repeat LRRNT PF01462.18 OWF52915.1 - 0.00012 21.7 5.6 0.0004 19.9 2.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TMEM154 PF15102.6 OWF52915.1 - 0.0016 18.4 0.9 0.0033 17.4 0.9 1.5 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 OWF52915.1 - 0.043 13.2 0.3 0.071 12.5 0.3 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Glyco_hydro_72 PF03198.14 OWF52915.1 - 0.046 13.0 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Glucanosyltransferase Myticin-prepro PF10690.9 OWF52915.1 - 0.061 13.6 0.9 1.9 8.8 0.6 2.4 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel EphA2_TM PF14575.6 OWF52915.1 - 0.16 12.9 0.0 0.42 11.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 OWF52915.1 - 0.85 9.5 2.3 1.3 8.8 2.3 1.2 1 0 0 1 1 1 0 Rifin HTH_12 PF08461.10 OWF52916.1 - 0.00029 20.7 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain RhoGAP PF00620.27 OWF52917.1 - 9.4e-45 152.1 0.1 1.7e-44 151.3 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain SOAR PF16533.5 OWF52918.1 - 2.6e-32 110.8 0.5 1.2e-31 108.6 0.5 2.2 1 0 0 1 1 1 1 STIM1 Orai1-activating region SAM_2 PF07647.17 OWF52918.1 - 1.2e-08 34.9 0.0 3.1e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF52918.1 - 1.8e-06 28.3 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Stathmin PF00836.19 OWF52918.1 - 0.98 9.4 13.9 0.31 11.0 5.6 2.6 1 1 1 2 2 2 0 Stathmin family SRA1 PF07304.11 OWF52919.1 - 1.4e-24 86.6 7.3 2.4e-24 85.8 7.3 1.5 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 OWF52919.1 - 2.9e-05 24.1 2.4 7.9e-05 22.7 2.4 1.7 1 1 0 1 1 1 1 Prp18 domain AA_permease_2 PF13520.6 OWF52920.1 - 4.1e-64 217.0 50.5 5e-64 216.7 50.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF52920.1 - 3.3e-28 98.5 52.0 1.9e-27 96.0 52.0 1.8 1 1 0 1 1 1 1 Amino acid permease CW_binding_2 PF04122.12 OWF52921.1 - 0.069 13.8 0.1 4.1 8.1 0.1 3.0 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 Septin PF00735.18 OWF52922.1 - 7.2e-99 330.6 1.7 7.2e-99 330.6 1.7 1.9 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OWF52922.1 - 5.6e-05 23.2 1.4 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF52922.1 - 0.0013 18.7 1.1 0.47 10.3 0.0 2.9 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OWF52922.1 - 0.0069 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 OWF52922.1 - 0.0089 16.2 1.6 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OWF52922.1 - 0.01 16.1 2.9 0.034 14.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OWF52922.1 - 0.039 13.7 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OWF52922.1 - 0.44 11.1 0.0 0.44 11.1 0.0 2.9 2 2 1 3 3 3 0 ABC transporter GTP_EFTU PF00009.27 OWF52922.1 - 1.5 8.3 13.3 10 5.6 0.1 3.3 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.17 OWF52922.1 - 2 8.4 11.2 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Beach PF02138.18 OWF52923.1 - 1.6e-122 408.2 0.8 2.8e-122 407.4 0.8 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 OWF52923.1 - 3e-111 371.2 5.0 3e-111 371.2 5.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 OWF52923.1 - 3.7e-73 244.7 7.4 3.7e-73 244.7 7.4 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 OWF52923.1 - 1.9e-27 95.3 0.0 1.9e-27 95.3 0.0 2.5 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OWF52923.1 - 3.5e-12 46.7 0.0 7.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 OWF52923.1 - 1.9e-09 38.0 6.1 0.0046 17.8 0.2 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF4800 PF16057.5 OWF52923.1 - 3e-05 23.4 0.2 9.4e-05 21.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) UMP1 PF05348.11 OWF52924.1 - 2.8e-31 108.2 0.5 3.7e-31 107.8 0.5 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase_Tyr PF07714.17 OWF52925.1 - 5e-90 301.3 0.0 8.4e-90 300.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF52925.1 - 2.6e-39 135.2 0.2 2.8e-26 92.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 OWF52925.1 - 2.3e-32 111.4 15.1 5.8e-10 39.6 0.0 7.3 6 2 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 OWF52925.1 - 2.6e-31 107.5 8.4 2.8e-10 40.1 0.0 7.0 6 1 0 6 6 6 4 Immunoglobulin I-set domain ig PF00047.25 OWF52925.1 - 3.3e-21 75.2 5.2 1.5e-05 25.0 0.1 6.5 5 1 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 OWF52925.1 - 2.7e-18 66.1 15.4 0.00026 21.2 0.0 8.0 7 1 0 7 7 7 3 Immunoglobulin domain V-set PF07686.17 OWF52925.1 - 4.8e-10 39.6 11.5 0.0043 17.2 0.2 6.0 5 1 0 5 5 5 4 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 OWF52925.1 - 0.00017 21.8 0.5 0.44 10.8 0.0 3.1 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 OWF52925.1 - 0.00099 19.1 1.8 3.7 7.7 0.0 4.8 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 OWF52925.1 - 0.0012 18.4 0.1 1 9.0 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin domain Syndecan PF01034.20 OWF52925.1 - 0.016 15.1 4.2 5.8 6.9 4.2 3.5 3 0 0 3 3 3 0 Syndecan domain EphA2_TM PF14575.6 OWF52925.1 - 0.059 14.3 0.0 0.21 12.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ASFV_J13L PF05568.11 OWF52925.1 - 0.2 11.4 0.7 0.57 9.9 0.2 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein RIFIN PF02009.16 OWF52925.1 - 0.21 11.5 3.1 0.46 10.3 1.7 2.1 2 0 0 2 2 2 0 Rifin Myotub-related PF06602.14 OWF52926.1 - 4.2e-152 506.1 0.1 5.8e-152 505.7 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 OWF52926.1 - 1.3e-17 63.7 0.0 3.2e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 OWF52926.1 - 7e-05 22.5 0.7 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 OWF52926.1 - 0.00085 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain 3-PAP PF12578.8 OWF52926.1 - 0.0073 16.1 1.4 0.03 14.1 1.4 2.1 1 1 0 1 1 1 1 Myotubularin-associated protein Y_phosphatase3 PF13350.6 OWF52926.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3844 PF12955.7 OWF52926.1 - 0.12 12.5 0.3 0.27 11.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) PGK PF00162.19 OWF52928.1 - 1.9e-127 425.3 1.6 2.2e-127 425.1 1.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Cadherin PF00028.17 OWF52930.1 - 0 1634.7 106.5 1.9e-24 85.9 0.0 34.4 34 0 0 34 34 34 34 Cadherin domain Cadherin_2 PF08266.12 OWF52930.1 - 1.1e-36 124.5 6.9 0.24 11.2 0.0 21.1 23 0 0 23 23 23 8 Cadherin-like Laminin_G_2 PF02210.24 OWF52930.1 - 2.7e-20 73.2 0.6 2.2e-18 67.1 0.0 3.5 2 0 0 2 2 2 1 Laminin G domain RET_CLD1 PF17756.1 OWF52930.1 - 9.7e-19 67.9 0.0 0.25 11.7 0.0 16.0 21 0 0 21 21 19 2 RET Cadherin like domain 1 Cadherin_3 PF16184.5 OWF52930.1 - 2.3e-18 66.2 64.6 0.00034 20.6 0.3 20.5 24 0 0 24 24 24 7 Cadherin-like Laminin_G_1 PF00054.23 OWF52930.1 - 6.4e-17 62.0 1.5 1.5e-16 60.8 0.0 2.5 3 0 0 3 3 1 1 Laminin G domain EGF PF00008.27 OWF52930.1 - 2.3e-15 56.6 59.8 4.1e-07 30.2 8.3 5.2 5 0 0 5 5 5 4 EGF-like domain Adeno_E3_CR2 PF02439.15 OWF52930.1 - 0.051 13.3 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3313 PF11769.8 OWF52930.1 - 0.092 12.6 1.4 20 4.9 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3313) PepSY PF03413.19 OWF52930.1 - 0.098 13.2 9.0 0.37 11.4 0.3 6.2 6 0 0 6 6 6 0 Peptidase propeptide and YPEB domain Phage_holin_2_4 PF16082.5 OWF52930.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3642 PF12182.8 OWF52930.1 - 0.45 10.8 3.2 11 6.4 0.1 4.4 4 0 0 4 4 4 0 Bacterial lipoprotein hEGF PF12661.7 OWF52930.1 - 2.8 8.7 55.1 0.014 16.0 7.5 5.8 6 0 0 6 6 5 0 Human growth factor-like EGF FSA_C PF10479.9 OWF52931.1 - 7.8e-189 629.2 15.5 1.9e-157 525.4 0.2 3.3 2 1 1 3 3 3 2 Fragile site-associated protein C-terminus Pet191_N PF10203.9 OWF52932.1 - 2e-22 79.3 8.0 2.3e-22 79.1 8.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Kinesin PF00225.23 OWF52933.1 - 5e-122 407.0 0.0 1e-121 406.0 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF52933.1 - 3e-26 92.1 0.1 1e-25 90.4 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Glyco_hydro_30 PF02055.16 OWF52934.1 - 3.8e-54 184.0 2.7 4.9e-54 183.6 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OWF52934.1 - 5.6e-16 58.5 2.4 1.4e-15 57.2 2.4 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 OWF52934.1 - 1.1e-15 57.7 1.4 1.6e-15 57.2 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OWF52934.1 - 2.9e-08 33.7 1.0 1.1e-07 31.9 1.0 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF2193 PF09959.9 OWF52935.1 - 0.023 13.2 0.6 0.031 12.7 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) DUF5390 PF17365.2 OWF52935.1 - 0.039 14.2 0.2 0.077 13.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5390) TraF PF13728.6 OWF52935.1 - 0.068 13.0 0.4 0.13 12.0 0.3 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein HSP70 PF00012.20 OWF52936.1 - 0.022 12.9 0.3 0.057 11.6 0.1 1.6 1 1 0 1 1 1 0 Hsp70 protein MetOD2 PF18548.1 OWF52936.1 - 0.044 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Metanogen output domain 2 TA_inhibitor PF17574.2 OWF52936.1 - 0.14 12.2 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of toxin/antitoxin system (Gp4.5) BBS2_C PF14782.6 OWF52937.1 - 1.4e-05 24.1 0.2 5.2e-05 22.2 0.1 2.0 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 OWF52937.1 - 0.00096 19.2 0.0 0.0032 17.5 0.0 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region SprA-related PF12118.8 OWF52937.1 - 0.16 11.1 0.5 0.24 10.5 0.5 1.2 1 0 0 1 1 1 0 SprA-related family DUF3368 PF11848.8 OWF52937.1 - 1.4 8.8 3.2 13 5.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) bZIP_2 PF07716.15 OWF52939.1 - 7.4e-06 26.0 18.1 7.4e-06 26.0 18.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF52939.1 - 0.00012 22.1 19.5 0.00012 22.1 19.5 1.9 2 0 0 2 2 2 1 bZIP transcription factor Pep_M12B_propep PF01562.19 OWF52939.1 - 0.044 14.0 1.9 0.077 13.2 1.9 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide RR_TM4-6 PF06459.12 OWF52939.1 - 0.085 12.7 6.8 0.096 12.5 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tho2 PF11262.8 OWF52939.1 - 0.15 11.3 6.0 0.21 10.8 6.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Blt1 PF12754.7 OWF52941.1 - 0.49 10.7 24.1 7.1 6.9 0.0 6.4 5 1 1 6 6 6 0 Blt1 N-terminal domain bZIP_2 PF07716.15 OWF52942.1 - 3.7e-05 23.7 5.2 6.3e-05 23.0 4.0 2.1 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OWF52942.1 - 0.0022 18.1 7.9 0.0068 16.5 7.9 1.9 1 0 0 1 1 1 1 bZIP transcription factor JIP_LZII PF16471.5 OWF52943.1 - 0.0016 18.5 3.0 0.0016 18.5 3.0 1.8 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II HLH PF00010.26 OWF52944.1 - 2.3e-17 62.7 0.1 3.8e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2353 PF09789.9 OWF52944.1 - 0.0055 16.1 0.7 0.0082 15.5 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Anthrax_toxA PF03497.16 OWF52944.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Anthrax toxin LF subunit TPR_MLP1_2 PF07926.12 OWF52944.1 - 0.042 13.9 1.6 0.092 12.8 1.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ComGG PF14173.6 OWF52944.1 - 0.052 14.0 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 ComG operon protein 7 Rootletin PF15035.6 OWF52944.1 - 0.097 12.7 2.5 0.17 11.9 2.5 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Med13_C PF06333.12 OWF52944.1 - 0.67 9.2 3.9 0.96 8.6 3.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SRP-alpha_N PF04086.13 OWF52945.1 - 1.6e-60 205.5 10.4 1.6e-60 205.5 10.4 1.4 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 OWF52945.1 - 5.8e-50 169.7 0.6 2.8e-49 167.4 0.6 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OWF52945.1 - 4.6e-09 36.4 0.1 2.1e-08 34.3 0.1 2.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OWF52945.1 - 2.7e-05 23.3 0.0 5.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 OWF52945.1 - 7.2e-05 22.9 0.0 0.0003 20.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 OWF52945.1 - 0.00076 19.4 0.0 0.0028 17.6 0.0 2.0 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 OWF52945.1 - 0.0017 18.7 0.0 0.0062 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 OWF52945.1 - 0.0054 16.8 0.0 0.024 14.7 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUIM_assoc PF16619.5 OWF52945.1 - 0.006 16.6 0.1 0.018 15.1 0.1 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Fer4_NifH PF00142.18 OWF52945.1 - 0.008 15.6 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 OWF52945.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_trans_A_1 PF09318.10 OWF52945.1 - 0.023 14.4 0.6 0.058 13.1 0.6 1.6 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A SRX PF09201.10 OWF52945.1 - 0.023 14.5 0.7 0.076 12.8 0.5 2.1 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit VirC1 PF07015.11 OWF52945.1 - 0.065 12.5 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 VirC1 protein AAA_22 PF13401.6 OWF52945.1 - 0.12 12.7 0.7 1.3 9.3 0.0 2.9 2 1 2 4 4 4 0 AAA domain Cdh1_DBD_1 PF18196.1 OWF52946.1 - 0.075 13.4 0.0 0.075 13.4 0.0 3.3 1 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 DUF1664 PF07889.12 OWF52946.1 - 0.15 12.1 16.9 2.9 7.9 4.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ERM PF00769.19 OWF52946.1 - 0.38 10.5 29.5 1.7 8.4 29.4 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1241 PF06840.11 OWF52946.1 - 0.88 9.2 8.3 0.072 12.7 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1241) BST2 PF16716.5 OWF52946.1 - 1.3 9.7 19.7 0.86 10.2 7.7 3.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Tropomyosin PF00261.20 OWF52946.1 - 1.7 7.9 29.5 5.2 6.4 29.5 1.7 1 1 0 1 1 1 0 Tropomyosin DUF3450 PF11932.8 OWF52946.1 - 2.6 7.3 12.6 3.7 6.8 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 OWF52946.1 - 2.7 7.8 25.5 1.5 8.6 5.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Fez1 PF06818.15 OWF52946.1 - 3.5 8.0 28.7 1.8 9.0 23.1 2.8 2 1 1 3 3 3 0 Fez1 CENP-F_leu_zip PF10473.9 OWF52946.1 - 3.7 7.6 33.9 0.85 9.6 13.4 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 OWF52946.1 - 3.7 5.6 26.6 0.21 9.7 8.6 3.0 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA UPF0242 PF06785.11 OWF52946.1 - 6.6 6.8 20.9 6.9 6.7 17.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PRO8NT PF08082.11 OWF52947.1 - 0.02 14.8 1.0 0.69 9.8 0.3 2.2 1 1 1 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain Anticodon_1 PF08264.13 OWF52947.1 - 0.13 12.2 7.3 2.6 8.0 1.0 2.9 1 1 2 3 3 3 0 Anticodon-binding domain of tRNA Zea_mays_MuDR PF05928.11 OWF52947.1 - 1.6 8.3 7.2 19 4.8 0.2 3.1 1 1 2 3 3 3 0 Zea mays MURB-like protein (MuDR) Tup_N PF08581.10 OWF52950.1 - 0.08 13.2 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Tup N-terminal DBB PF14545.6 OWF52951.1 - 2.1e-07 30.9 0.0 1.4e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 Dof, BCAP, and BANK (DBB) motif, Ank_2 PF12796.7 OWF52951.1 - 0.00044 20.8 0.0 0.00099 19.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIR_3 PF18567.1 OWF52951.1 - 0.015 15.3 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain Ank_3 PF13606.6 OWF52951.1 - 0.14 12.8 0.1 0.56 10.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Dsh_C PF12316.8 OWF52951.1 - 4.2 7.7 16.9 0.077 13.4 8.2 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal RasGEF PF00617.19 OWF52952.1 - 4.9e-51 173.4 2.3 1.9e-50 171.5 0.8 2.6 3 0 0 3 3 3 1 RasGEF domain PDZ PF00595.24 OWF52952.1 - 5.3e-11 42.7 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RasGEF_N PF00618.20 OWF52952.1 - 6e-10 39.3 0.3 3.7e-08 33.6 0.3 2.9 1 1 0 1 1 1 1 RasGEF N-terminal motif cNMP_binding PF00027.29 OWF52952.1 - 7e-09 35.7 0.0 3.5e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RA PF00788.23 OWF52952.1 - 1.7e-08 35.0 0.1 5.1e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_6 PF17820.1 OWF52952.1 - 1.1e-06 28.3 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF52952.1 - 0.0044 17.3 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain MutL_C PF08676.11 OWF52953.1 - 6.2e-32 110.4 0.0 1.3e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OWF52953.1 - 1.1e-23 83.1 0.4 4.7e-23 81.1 0.1 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OWF52953.1 - 8.8e-14 51.5 0.9 4.9e-12 45.8 0.2 3.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OWF52953.1 - 1.4e-05 25.5 1.5 7.5e-05 23.2 0.5 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRM_1 PF00076.22 OWF52954.1 - 7.2e-35 118.6 0.4 1e-16 60.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF52954.1 - 1.2e-06 28.3 0.0 0.31 10.9 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 OWF52954.1 - 1.4e-05 25.2 0.0 0.007 16.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_9 PF18444.1 OWF52954.1 - 0.055 13.3 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif Spo7_2_N PF15407.6 OWF52954.1 - 0.2 11.3 0.0 9.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein family 7 HgmA PF04209.13 OWF52955.1 - 6.5e-215 713.7 0.2 7.3e-215 713.5 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF4071 PF13281.6 OWF52956.1 - 2.7e-140 467.6 0.5 1.6e-130 435.5 0.2 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4071) Pkinase PF00069.25 OWF52956.1 - 1.1e-63 215.1 0.0 4.5e-63 213.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF52956.1 - 1.5e-41 142.4 0.0 3.5e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF52956.1 - 0.014 14.2 0.0 0.039 12.7 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OWF52956.1 - 0.018 14.4 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like TetR_C_8 PF14278.6 OWF52956.1 - 0.28 11.3 1.7 7.2 6.8 1.1 2.6 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Sec63 PF02889.16 OWF52958.1 - 7.1e-21 74.5 9.8 1.2e-10 41.0 0.5 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 OWF52958.1 - 1.7e-16 60.1 1.6 2.9e-16 59.3 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain FliG_N PF14842.6 OWF52958.1 - 0.041 14.4 1.8 0.053 14.1 0.1 2.1 2 0 0 2 2 2 0 FliG N-terminal domain FixQ PF05545.11 OWF52958.1 - 0.91 9.5 4.5 18 5.4 0.2 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ INCENP_ARK-bind PF03941.15 OWF52959.1 - 8e-17 60.9 0.8 8e-17 60.9 0.8 3.2 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Ras PF00071.22 OWF52960.1 - 5.9e-57 191.8 0.3 6.8e-57 191.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF52960.1 - 5.6e-20 71.7 0.0 8.4e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF52960.1 - 3.5e-10 39.6 0.0 4.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF52960.1 - 3.3e-06 26.8 0.0 6.2e-06 25.9 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF52960.1 - 2.4e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF52960.1 - 0.00039 20.3 1.6 0.0054 16.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OWF52960.1 - 0.0029 17.5 2.9 0.37 10.7 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OWF52960.1 - 0.062 12.8 0.3 0.15 11.6 0.3 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B NPHI_C PF08469.10 OWF52960.1 - 0.093 12.7 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Adaptin_N PF01602.20 OWF52961.1 - 9.5e-114 380.8 8.5 1.3e-113 380.3 8.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 OWF52961.1 - 4e-59 198.5 0.3 9.5e-59 197.3 0.3 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 OWF52961.1 - 1.4e-58 196.4 0.1 3.8e-58 195.0 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 OWF52961.1 - 7e-11 42.4 0.2 0.0041 17.5 0.0 6.2 4 3 2 7 7 7 3 HEAT repeats HEAT PF02985.22 OWF52961.1 - 9.4e-11 41.0 0.4 0.021 15.0 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 OWF52961.1 - 1.1e-10 41.8 7.1 3.5e-07 30.4 0.1 4.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OWF52961.1 - 5.6e-08 33.1 0.6 0.6 10.7 0.0 5.6 6 0 0 6 6 6 2 HEAT-like repeat Coatomer_g_Cpla PF16381.5 OWF52961.1 - 0.00039 20.5 0.1 0.0011 19.0 0.0 1.9 2 0 0 2 2 1 1 Coatomer subunit gamma-1 C-terminal appendage platform Arm PF00514.23 OWF52961.1 - 0.00042 20.3 0.2 6 7.1 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 OWF52961.1 - 0.0055 16.3 0.3 0.18 11.4 0.0 3.2 2 1 2 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF5578 PF17741.1 OWF52961.1 - 0.24 10.8 2.9 0.45 9.9 0.3 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 OWF52961.1 - 0.3 11.2 2.1 54 3.9 0.3 4.3 4 0 0 4 4 4 0 V-ATPase subunit H Glyco_transf_10 PF00852.19 OWF52962.1 - 1.9e-45 154.8 1.7 2.5e-45 154.4 1.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF52962.1 - 8.6e-14 51.9 1.6 1e-13 51.7 0.3 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal CH PF00307.31 OWF52963.1 - 3e-11 43.4 0.1 4.3e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 OWF52963.1 - 3.3e-11 42.6 3.5 8.4e-11 41.3 3.5 1.8 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 OWF52964.1 - 1e-09 38.6 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 OWF52964.1 - 5.1e-09 35.6 2.0 8.7e-09 34.9 2.0 1.4 1 0 0 1 1 1 1 Calponin family repeat Fucose_iso_N2 PF07882.12 OWF52964.1 - 0.049 13.2 0.1 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain DUF951 PF06107.11 OWF52964.1 - 0.11 12.4 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) HMGL-like PF00682.19 OWF52964.1 - 0.16 11.5 0.0 3.5 7.1 0.0 2.0 2 0 0 2 2 2 0 HMGL-like CH PF00307.31 OWF52965.1 - 2.8e-18 66.1 0.0 4.7e-18 65.4 0.0 1.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Calponin PF00402.18 OWF52965.1 - 1.7e-09 37.1 0.3 2.8e-09 36.4 0.3 1.4 1 0 0 1 1 1 1 Calponin family repeat Galactosyl_T PF01762.21 OWF52966.1 - 8.6e-33 113.8 0.1 1.5e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase WD40 PF00400.32 OWF52967.1 - 1.2e-18 67.1 23.2 0.0011 19.7 0.0 10.3 12 0 0 12 12 12 5 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OWF52967.1 - 6.4e-06 25.2 1.3 0.6 8.8 0.0 4.9 5 1 0 5 5 5 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 OWF52967.1 - 3.7e-05 23.9 0.1 0.15 12.4 0.0 5.2 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF52967.1 - 0.0015 17.3 0.2 0.88 8.1 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 TFIIA PF03153.13 OWF52967.1 - 0.059 13.4 18.5 0.097 12.7 18.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 OWF52967.1 - 3.3 5.8 31.7 4.9 5.2 31.7 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 OWF52967.1 - 4.3 6.9 34.9 8.6 5.9 34.9 1.4 1 0 0 1 1 1 0 PPP4R2 Ras PF00071.22 OWF52968.1 - 2.1e-48 164.0 0.0 2.4e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF52968.1 - 2.6e-26 92.2 0.0 3.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF52968.1 - 8.9e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF52968.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF52968.1 - 7.2e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF52968.1 - 0.0096 15.8 0.0 0.26 11.2 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OWF52968.1 - 0.055 13.0 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PI3K_C2 PF00792.24 OWF52968.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 GTP_EFTU PF00009.27 OWF52968.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OWF52968.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OWF52968.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Mcl1_mid PF12341.8 OWF52969.1 - 2.3e-95 319.4 0.0 4.9e-95 318.3 0.0 1.6 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 OWF52969.1 - 1.4e-16 60.6 5.8 1.5e-05 25.6 0.0 6.8 6 0 0 6 6 6 2 WD domain, G-beta repeat HMG_box PF00505.19 OWF52969.1 - 2.1e-10 40.8 0.3 6.9e-10 39.2 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box ANAPC4_WD40 PF12894.7 OWF52969.1 - 2.9e-09 37.1 1.3 6.3e-06 26.4 0.0 4.0 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF52969.1 - 8.8e-06 24.9 0.6 0.15 11.0 0.0 3.4 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein HMG_box_2 PF09011.10 OWF52969.1 - 0.0019 18.8 0.5 0.0054 17.3 0.5 1.8 1 0 0 1 1 1 1 HMG-box domain SOCS_box PF07525.16 OWF52970.1 - 8.9e-11 42.0 0.2 1.7e-10 41.1 0.2 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.24 OWF52970.1 - 1.3e-10 41.2 0.1 3.2e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 SH2 domain Translin PF01997.16 OWF52971.1 - 1.6e-60 204.6 0.4 2e-60 204.3 0.4 1.1 1 0 0 1 1 1 1 Translin family SpoIIID PF12116.8 OWF52971.1 - 0.13 12.4 0.3 8.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Stage III sporulation protein D DUF2816 PF10992.8 OWF52972.1 - 0.0015 18.3 14.6 0.28 11.1 0.3 4.5 1 1 1 4 4 4 2 Protein of unknown function (DUF2816) DUF2110 PF09883.9 OWF52972.1 - 0.024 14.2 9.3 1.7 8.2 0.7 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) UvrD_C_2 PF13538.6 OWF52972.1 - 0.028 14.2 26.5 4.1 7.3 0.2 6.9 1 1 5 6 6 6 0 UvrD-like helicase C-terminal domain DNA_ligase_ZBD PF03119.16 OWF52972.1 - 0.13 12.3 9.2 57 3.9 0.1 6.1 5 2 0 5 5 5 0 NAD-dependent DNA ligase C4 zinc finger domain zf-met PF12874.7 OWF52972.1 - 0.36 11.3 3.9 99 3.5 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SIT PF15330.6 OWF52972.1 - 0.63 10.5 12.4 3.4 8.1 5.6 2.5 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT RPA_C PF08784.11 OWF52972.1 - 0.88 10.3 3.8 80 4.0 3.8 3.1 1 1 0 1 1 1 0 Replication protein A C terminal BEN PF10523.9 OWF52973.1 - 1.9e-11 44.1 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 BEN domain PMP22_Claudin PF00822.20 OWF52974.1 - 5.9e-13 49.0 10.2 7.2e-13 48.7 10.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF52974.1 - 7.2e-09 35.7 22.2 1e-08 35.2 10.7 2.7 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF52974.1 - 0.00034 20.6 8.6 0.00052 20.0 8.6 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DuoxA PF10204.9 OWF52974.1 - 0.0047 16.0 4.1 0.0047 16.0 4.1 1.8 2 0 0 2 2 2 1 Dual oxidase maturation factor L_HMGIC_fpl PF10242.9 OWF52974.1 - 0.018 15.3 8.9 0.03 14.5 8.8 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Sdh_cyt PF01127.22 OWF52974.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.4 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C3HC4_2 PF13923.6 OWF52975.1 - 2.5e-07 30.4 10.8 2.5e-07 30.4 10.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF52975.1 - 2.5e-07 30.9 12.4 2.5e-07 30.9 12.4 2.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF52975.1 - 3.5e-06 26.8 9.5 3.5e-06 26.8 9.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF52975.1 - 3.6e-06 26.7 11.3 3.6e-06 26.7 11.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF52975.1 - 3e-05 23.9 10.8 3e-05 23.9 10.8 2.7 2 1 0 2 2 1 1 zinc-RING finger domain NHL PF01436.21 OWF52975.1 - 0.00019 21.3 0.1 0.014 15.4 0.0 3.4 3 0 0 3 3 3 1 NHL repeat zf-C3HC4_4 PF15227.6 OWF52975.1 - 0.00038 20.6 10.3 0.00038 20.6 10.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF52975.1 - 0.0015 18.3 10.5 0.0015 18.3 10.5 3.1 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OWF52975.1 - 0.0016 18.4 13.5 0.0058 16.6 13.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 OWF52975.1 - 0.0036 17.4 4.9 0.0036 17.4 4.9 2.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 Apolipoprotein PF01442.18 OWF52975.1 - 0.0046 16.8 9.1 0.0085 16.0 9.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain zf-rbx1 PF12678.7 OWF52975.1 - 0.013 15.8 9.0 0.013 15.8 9.0 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain DUF885 PF05960.11 OWF52975.1 - 0.079 12.6 0.8 0.12 12.0 0.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) HSP70 PF00012.20 OWF52975.1 - 0.35 9.0 11.1 0.55 8.3 11.1 1.2 1 0 0 1 1 1 0 Hsp70 protein FTCD_C PF04961.12 OWF52975.1 - 0.95 9.2 3.2 0.71 9.6 1.5 1.6 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DUF1043 PF06295.12 OWF52975.1 - 1 9.3 11.6 1.9 8.5 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 OWF52975.1 - 1.4 8.4 7.6 2.3 7.7 7.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 OWF52975.1 - 4.5 6.5 10.9 9 5.5 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SYCP2_SLD PF18584.1 OWF52976.1 - 0.039 14.2 1.0 0.32 11.2 0.1 2.5 2 0 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain Ribosomal_L32p PF01783.23 OWF52977.1 - 0.0066 16.7 0.4 1.7 9.0 0.2 2.4 2 0 0 2 2 2 2 Ribosomal L32p protein family Death PF00531.22 OWF52977.1 - 0.0091 16.1 0.4 0.033 14.3 0.3 2.0 2 0 0 2 2 2 1 Death domain DUF3884 PF13024.6 OWF52978.1 - 0.094 12.3 0.3 1.3 8.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3884) FMO-like PF00743.19 OWF52979.1 - 3.5e-183 609.9 0.0 4.3e-183 609.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF52979.1 - 9e-16 58.0 0.0 1e-11 44.6 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF52979.1 - 7.9e-11 41.7 0.0 1.5e-08 34.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OWF52979.1 - 2.5e-09 36.8 0.0 4.2e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF52979.1 - 8e-05 22.8 0.1 0.00039 20.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF52979.1 - 0.045 13.0 0.3 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 OWF52979.1 - 0.061 12.0 0.5 7.9 5.1 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 OWF52979.1 - 0.1 13.2 0.6 2.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OWF52979.1 - 0.14 11.5 0.2 0.68 9.3 0.1 2.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lactococcin_972 PF09683.10 OWF52980.1 - 2.2 8.9 19.8 30 5.3 0.3 4.8 1 1 3 4 4 4 0 Bacteriocin (Lactococcin_972) DHFR_1 PF00186.19 OWF52981.1 - 1.9e-22 79.7 0.0 2.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Septin PF00735.18 OWF52982.1 - 2.2e-124 414.3 0.4 2.2e-124 414.3 0.4 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OWF52982.1 - 1e-09 38.5 0.3 2.9e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF52982.1 - 1e-06 28.8 1.8 1.7e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 OWF52982.1 - 0.00021 20.7 0.0 0.00048 19.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 OWF52982.1 - 0.00025 20.7 0.4 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 Ras family Dynamin_N PF00350.23 OWF52982.1 - 0.00044 20.3 5.2 0.35 10.9 0.0 3.3 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 OWF52982.1 - 0.00097 18.7 1.7 0.02 14.4 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OWF52982.1 - 0.0015 19.1 1.2 0.0069 16.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 OWF52982.1 - 0.0026 17.9 0.0 0.0096 16.1 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OWF52982.1 - 0.003 18.1 2.4 0.003 18.1 2.4 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF52982.1 - 0.01 16.1 0.2 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF52982.1 - 0.017 14.6 0.1 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 OWF52982.1 - 0.05 12.6 0.8 0.076 12.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 OWF52982.1 - 0.053 13.9 0.2 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OWF52982.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 OWF52983.1 - 2.4e-129 430.6 0.0 3.7e-129 430.0 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OWF52983.1 - 1.5e-07 31.5 0.1 4.5e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF52983.1 - 2e-07 31.1 0.1 1.9e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OWF52983.1 - 1.1e-05 25.1 0.2 0.024 14.2 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 OWF52983.1 - 2e-05 24.0 1.6 8.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 OWF52983.1 - 0.00024 20.8 0.0 0.0008 19.0 0.0 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OWF52983.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 OWF52983.1 - 0.0025 18.3 0.1 0.0096 16.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OWF52983.1 - 0.006 17.0 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF52983.1 - 0.0061 16.8 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OWF52983.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OWF52983.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 OWF52983.1 - 0.071 13.2 5.4 0.6 10.2 0.1 3.0 3 1 1 4 4 4 0 Dynamin family Pox_A32 PF04665.12 OWF52983.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein GCIP PF13324.6 OWF52983.1 - 0.15 11.6 4.7 2.6 7.6 1.2 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting PDZ_6 PF17820.1 OWF52984.1 - 0.00012 21.8 8.0 9.8 6.1 0.3 6.2 2 2 4 6 6 6 3 PDZ domain P2_N PF18628.1 OWF52984.1 - 0.0099 15.6 3.9 2.4 7.9 0.4 3.4 1 1 3 4 4 4 3 Viral coat protein P2 N-terminal domain YokU PF14122.6 OWF52984.1 - 0.063 13.3 0.0 11 6.1 0.0 2.2 1 1 0 2 2 2 0 YokU-like protein, putative antitoxin LRR_8 PF13855.6 OWF52984.1 - 0.12 12.1 10.8 0.12 12.1 2.3 2.2 1 1 1 2 2 2 0 Leucine rich repeat SH2 PF00017.24 OWF52985.1 - 7.6e-14 51.6 0.2 1.4e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 SH2 domain Phe_ZIP PF08916.11 OWF52985.1 - 7.1e-11 42.6 0.0 1.3e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Phenylalanine zipper PH PF00169.29 OWF52985.1 - 2.9e-08 34.2 0.0 5.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Y2_Tnp PF04986.13 OWF52985.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative transposase zf-His_Me_endon PF05551.11 OWF52986.1 - 1.3e-10 41.5 1.3 1.7e-10 41.2 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease SVWC PF15430.6 OWF52986.1 - 0.031 14.5 0.2 0.056 13.7 0.2 1.4 1 0 0 1 1 1 0 Single domain von Willebrand factor type C MFS_1 PF07690.16 OWF52987.1 - 7.2e-37 127.1 39.6 1.2e-35 123.0 31.2 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.13 OWF52987.1 - 0.3 9.4 9.3 1.3 7.3 4.3 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector EPL1 PF10513.9 OWF52988.1 - 0.21 12.0 13.1 2.1 8.7 1.1 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like PDZ PF00595.24 OWF52989.1 - 6.8e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF52989.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF52989.1 - 0.0019 18.5 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain TPR_19 PF14559.6 OWF52990.1 - 2.9e-18 66.1 10.8 8.3e-06 26.2 2.5 6.6 6 2 2 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF52990.1 - 2.5e-13 50.0 25.3 2.1e-06 27.9 0.1 5.5 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OWF52990.1 - 1.2e-09 38.2 3.7 0.045 14.6 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF52990.1 - 1e-08 35.2 2.1 0.0029 17.7 1.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF52990.1 - 3.4e-08 33.0 35.3 0.03 14.4 0.1 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 OWF52990.1 - 3.1e-07 30.9 1.8 0.65 10.7 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF52990.1 - 8.7e-06 25.3 18.2 0.098 12.5 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 OWF52990.1 - 7e-05 23.2 15.9 0.44 11.3 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF52990.1 - 0.00025 20.9 10.2 0.22 11.6 0.4 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF52990.1 - 0.0021 18.1 19.4 0.41 11.0 0.0 6.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF52990.1 - 0.007 16.7 10.5 0.32 11.5 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR_2 PF13041.6 OWF52990.1 - 0.01 16.0 3.5 4.9 7.4 0.0 4.2 3 1 1 4 4 4 0 PPR repeat family TPR_4 PF07721.14 OWF52990.1 - 0.011 16.2 0.0 22 6.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 OWF52990.1 - 0.051 13.7 0.1 27 5.0 0.1 3.1 2 1 1 3 3 3 0 Pentatricopeptide repeat domain PPR PF01535.20 OWF52990.1 - 0.45 10.9 6.3 12 6.5 0.1 4.7 6 0 0 6 6 5 0 PPR repeat Fis1_TPR_C PF14853.6 OWF52990.1 - 0.54 10.4 7.6 9.5 6.4 0.8 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OWF52990.1 - 1.6 9.1 20.4 1.5 9.2 0.0 6.1 7 3 0 7 7 6 0 Tetratricopeptide repeat PDZ PF00595.24 OWF52991.1 - 2.9e-12 46.8 0.0 3.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF52991.1 - 1.3e-05 24.9 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF52991.1 - 0.00049 20.4 0.0 0.0032 17.8 0.0 2.0 1 1 1 2 2 2 1 PDZ domain DUF4749 PF15936.5 OWF52991.1 - 0.032 15.3 0.0 0.042 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4749) SSF PF00474.17 OWF52992.1 - 4.1e-35 121.4 24.0 6.2e-35 120.8 24.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SpoVAB PF13782.6 OWF52992.1 - 0.86 9.9 10.2 0.13 12.6 2.6 3.0 3 0 0 3 3 3 0 Stage V sporulation protein AB FixQ PF05545.11 OWF52992.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.3 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ PMM PF03332.13 OWF52993.1 - 4.4e-102 340.5 1.3 5.1e-102 340.3 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OWF52993.1 - 2.4e-06 27.5 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OWF52993.1 - 0.41 10.7 2.7 6.8 6.7 0.0 2.7 1 1 2 3 3 3 0 Haloacid dehalogenase-like hydrolase Ependymin PF00811.18 OWF52994.1 - 1.8e-10 41.2 0.3 4.6e-10 39.8 0.1 1.7 2 0 0 2 2 2 1 Ependymin Exo_endo_phos PF03372.23 OWF52995.1 - 0.00061 19.4 0.0 0.0014 18.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 OWF52996.1 - 2.1e-05 24.2 0.0 5.2e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OWF52996.1 - 0.13 12.1 0.0 2 8.3 0.0 2.4 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase Ephrin_rec_like PF07699.13 OWF52998.1 - 2.3e-31 107.3 47.1 1.3e-12 47.2 5.7 6.1 3 2 2 5 5 5 4 Putative ephrin-receptor like TSP_1 PF00090.19 OWF52998.1 - 6.9e-12 45.4 9.5 6.9e-12 45.4 9.5 4.7 4 0 0 4 4 4 1 Thrombospondin type 1 domain EGF PF00008.27 OWF52998.1 - 2.1e-11 43.9 31.9 5.6e-07 29.7 6.5 5.2 4 0 0 4 4 4 2 EGF-like domain HYR PF02494.16 OWF52998.1 - 4.3e-08 33.4 0.1 1.4e-07 31.8 0.1 2.0 1 0 0 1 1 1 1 HYR domain hEGF PF12661.7 OWF52998.1 - 0.0009 19.8 8.1 0.0009 19.8 8.1 6.0 5 0 0 5 5 5 2 Human growth factor-like EGF DUF5011 PF16403.5 OWF52998.1 - 0.16 12.1 0.2 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) EGF PF00008.27 OWF52999.1 - 2.6e-09 37.2 7.3 2.6e-09 37.2 7.3 3.7 4 0 0 4 4 4 2 EGF-like domain Sushi PF00084.20 OWF52999.1 - 2.9e-08 34.2 1.0 2.9e-08 34.2 1.0 4.1 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) HYR PF02494.16 OWF52999.1 - 3.2e-07 30.6 0.7 9.7e-07 29.0 0.2 2.0 2 0 0 2 2 2 1 HYR domain hEGF PF12661.7 OWF52999.1 - 1.3e-06 28.8 7.9 1.3e-06 28.8 7.9 4.6 3 1 0 3 3 3 1 Human growth factor-like EGF TSP_1 PF00090.19 OWF52999.1 - 0.00041 20.5 9.4 0.00041 20.5 9.4 3.3 1 1 1 2 2 2 1 Thrombospondin type 1 domain EGF_2 PF07974.13 OWF52999.1 - 0.0009 19.6 11.5 0.0009 19.6 11.5 4.3 4 1 0 4 4 4 1 EGF-like domain HYR PF02494.16 OWF53000.1 - 7.7e-29 99.8 4.1 7.9e-16 58.2 0.3 3.0 2 0 0 2 2 2 2 HYR domain Ephrin_rec_like PF07699.13 OWF53000.1 - 3.9e-26 90.6 45.7 1.9e-11 43.5 4.0 6.6 4 2 2 6 6 6 3 Putative ephrin-receptor like TSP_1 PF00090.19 OWF53000.1 - 1e-12 48.0 9.6 1e-12 48.0 9.6 5.6 4 0 0 4 4 3 1 Thrombospondin type 1 domain Laminin_G_3 PF13385.6 OWF53000.1 - 5e-11 43.0 1.2 9.6e-11 42.1 1.2 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 OWF53000.1 - 8.6e-11 41.9 28.4 7.2e-05 23.0 7.8 5.3 3 0 0 3 3 3 2 EGF-like domain Sushi PF00084.20 OWF53000.1 - 1.8e-06 28.5 14.8 0.00017 22.1 3.3 8.6 9 1 0 9 9 8 4 Sushi repeat (SCR repeat) hEGF PF12661.7 OWF53000.1 - 5.1e-06 26.9 23.3 0.00089 19.8 2.6 5.1 3 0 0 3 3 2 2 Human growth factor-like EGF DUF2318 PF10080.9 OWF53000.1 - 0.0045 17.1 17.7 0.51 10.5 1.6 4.1 2 1 1 3 3 3 2 Predicted membrane protein (DUF2318) Pentaxin PF00354.17 OWF53000.1 - 0.0074 16.0 0.5 0.015 15.0 0.5 1.4 1 0 0 1 1 1 1 Pentaxin family Gly-zipper_OmpA PF13436.6 OWF53000.1 - 0.68 9.8 6.6 1.7 8.5 6.6 1.6 1 0 0 1 1 1 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 OWF53000.1 - 0.76 9.6 6.7 2 8.2 6.7 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 OWF53000.1 - 2.8 8.0 8.8 9.2 6.4 8.8 1.9 1 0 0 1 1 1 0 Glycine zipper P4Ha_N PF08336.11 OWF53001.1 - 3.4e-20 72.5 0.4 3.4e-20 72.5 0.4 1.9 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 OWF53001.1 - 3.3e-14 53.5 0.0 6.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OWF53001.1 - 0.00011 22.7 0.0 0.0002 21.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1664 PF07889.12 OWF53001.1 - 0.087 12.9 0.4 0.21 11.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BLI1 PF17324.2 OWF53001.1 - 0.14 12.9 2.7 0.15 12.7 0.1 2.4 2 0 0 2 2 2 0 BLOC-1 interactor 1 RRM_1 PF00076.22 OWF53002.1 - 8e-33 112.1 0.9 9.7e-16 57.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 OWF53002.1 - 0.016 13.4 55.3 0.027 12.7 55.3 1.4 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 OWF53002.1 - 0.025 14.3 42.9 0.047 13.4 42.9 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Merozoite_SPAM PF07133.11 OWF53003.1 - 0.025 14.6 47.0 0.072 13.1 47.0 1.8 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 OWF53003.1 - 1.7 6.9 34.7 3.5 5.8 34.7 1.5 1 0 0 1 1 1 0 CDC45-like protein UPF0193 PF05250.11 OWF53004.1 - 2.3e-63 213.9 4.7 2.7e-63 213.7 4.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) MFS_1 PF07690.16 OWF53005.1 - 6.9e-20 71.3 8.9 8.6e-20 71.0 8.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TBCC PF07986.12 OWF53006.1 - 1e-46 157.5 2.8 1.8e-46 156.8 2.8 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OWF53006.1 - 6.1e-05 22.7 1.2 0.00012 21.7 1.2 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Coat_X PF07552.11 OWF53006.1 - 4 7.3 5.3 5.4 6.9 0.1 3.0 2 1 1 3 3 3 0 Spore Coat Protein X and V domain Ank_2 PF12796.7 OWF53007.1 - 4.1e-23 81.8 1.6 9.7e-05 22.9 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53007.1 - 1.3e-14 54.4 0.4 0.0013 19.3 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF53007.1 - 1.4e-13 50.7 4.5 0.0006 20.1 0.0 5.5 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF53007.1 - 1.6e-13 49.5 3.5 0.0034 17.7 0.0 7.6 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 OWF53007.1 - 1.1e-11 44.6 1.2 0.011 16.1 0.0 6.7 6 0 0 6 6 6 2 Ankyrin repeat DUF1843 PF08898.10 OWF53007.1 - 0.067 13.7 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Kinesin PF00225.23 OWF53008.1 - 5.9e-106 354.1 0.1 5.9e-106 354.1 0.1 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OWF53008.1 - 8e-24 84.3 0.2 8e-24 84.3 0.2 2.7 3 0 0 3 3 3 1 Microtubule binding WD40 PF00400.32 OWF53008.1 - 2.4e-21 75.6 10.9 0.00086 20.1 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat UDPGP PF01704.18 OWF53009.1 - 1.1e-67 228.5 0.0 1.5e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 OWF53009.1 - 0.039 14.3 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain NAD_binding_10 PF13460.6 OWF53010.1 - 4.3e-06 26.7 0.0 5.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OWF53010.1 - 0.015 15.7 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DIRP PF06584.13 OWF53011.1 - 1.4e-41 141.0 0.3 4e-41 139.5 0.3 1.8 1 0 0 1 1 1 1 DIRP DUF4795 PF16043.5 OWF53011.1 - 0.079 12.5 4.4 0.28 10.8 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4168 PF13767.6 OWF53011.1 - 0.16 13.1 0.4 0.44 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) DUF5567 PF17722.1 OWF53012.1 - 1.2e-21 77.7 13.9 5.3e-13 49.4 2.0 2.5 2 1 0 2 2 2 2 Family of unknown function (DUF5567) LIM PF00412.22 OWF53013.1 - 4.5e-27 94.1 26.5 1.8e-13 50.5 11.9 2.1 2 0 0 2 2 2 2 LIM domain RhoGEF PF00621.20 OWF53014.1 - 1.5e-42 145.9 2.7 3.3e-42 144.8 2.7 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 OWF53014.1 - 2.9e-10 40.6 0.0 1e-09 38.8 0.0 2.0 1 0 0 1 1 1 1 PH domain PhaP_Bmeg PF09602.10 OWF53015.1 - 0.048 13.6 0.2 4.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SNF PF00209.18 OWF53016.1 - 1.7e-204 680.4 32.9 1.9e-204 680.2 32.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF53017.1 - 2.6e-208 693.0 29.7 3e-208 692.7 29.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNARE_assoc PF09335.11 OWF53018.1 - 1.6e-21 77.0 7.0 2.4e-21 76.4 5.9 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Gemini_mov PF01708.16 OWF53018.1 - 0.011 15.5 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF4407 PF14362.6 OWF53018.1 - 0.07 12.5 0.1 0.19 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TTL PF03133.15 OWF53019.1 - 5.2e-108 360.6 0.8 6.4e-108 360.3 0.8 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OWF53019.1 - 2e-05 24.0 0.0 0.003 16.8 0.0 2.4 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OWF53019.1 - 0.014 14.7 0.0 0.063 12.5 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 OWF53019.1 - 0.18 11.3 0.0 0.82 9.2 0.0 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Pkinase PF00069.25 OWF53020.1 - 5.3e-57 193.2 0.0 4.2e-35 121.4 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF53020.1 - 5.2e-31 107.9 0.0 1e-22 80.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OWF53020.1 - 0.0007 19.0 0.5 0.0031 16.9 0.1 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OWF53020.1 - 0.0052 16.2 0.2 0.071 12.4 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF53020.1 - 0.029 14.3 0.1 0.075 12.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 OWF53021.1 - 6.2e-47 156.6 14.2 5.7e-10 39.6 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OWF53021.1 - 2.9e-29 101.9 3.9 5.1e-29 101.1 3.9 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 OWF53021.1 - 1.2e-13 51.2 0.0 1.5e-05 25.2 0.0 4.5 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF53021.1 - 5.1e-05 22.1 2.5 0.079 11.6 0.0 4.1 2 2 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF53021.1 - 0.00031 20.2 0.0 1.7 7.9 0.0 3.8 3 1 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 OWF53021.1 - 0.00097 18.2 0.1 5.6 5.8 0.0 3.9 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 OWF53022.1 - 1.6e-43 146.4 0.8 8.5e-18 63.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 OWF53022.1 - 1.8e-22 79.4 0.0 3.2e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_7 PF16367.5 OWF53022.1 - 3.1e-05 24.0 0.5 0.037 14.1 0.1 3.6 3 1 0 3 3 3 1 RNA recognition motif dsrm PF00035.26 OWF53022.1 - 0.00031 21.4 0.0 0.00082 20.0 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif RRM_5 PF13893.6 OWF53022.1 - 0.00034 20.2 0.0 0.9 9.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF53022.1 - 0.0044 16.8 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OWF53022.1 - 0.0062 16.5 0.8 13 5.9 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif ERp29 PF07749.12 OWF53022.1 - 0.024 15.5 0.2 0.085 13.8 0.0 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain SET_assoc PF11767.8 OWF53022.1 - 0.034 13.8 0.1 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 OWF53022.1 - 0.1 12.8 0.0 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 RRM-like domain HEAT PF02985.22 OWF53023.1 - 9.2e-07 28.6 1.0 0.1 12.9 0.2 3.4 3 0 0 3 3 3 2 HEAT repeat Atx10homo_assoc PF09759.9 OWF53023.1 - 8e-06 25.8 0.5 0.00013 21.9 0.2 2.7 1 1 2 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 OWF53023.1 - 3.3e-05 24.2 0.1 0.0018 18.6 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats Fes1 PF08609.10 OWF53023.1 - 0.00053 20.8 5.5 0.00064 20.5 1.2 2.8 3 0 0 3 3 2 1 Nucleotide exchange factor Fes1 V-ATPase_H_C PF11698.8 OWF53023.1 - 0.00085 19.4 1.8 0.85 9.7 0.2 2.9 2 1 0 2 2 2 2 V-ATPase subunit H Rcd1 PF04078.13 OWF53023.1 - 0.0009 18.6 0.1 0.0035 16.7 0.0 1.8 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like HEAT_EZ PF13513.6 OWF53023.1 - 0.0011 19.4 0.4 0.11 13.0 0.1 3.5 2 1 1 3 3 3 2 HEAT-like repeat VHS PF00790.19 OWF53023.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 VHS domain Mog1 PF04603.12 OWF53023.1 - 0.021 15.2 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Ran-interacting Mog1 protein DUF4704 PF15787.5 OWF53023.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Cnd1 PF12717.7 OWF53023.1 - 0.39 10.7 2.3 1.1 9.3 0.1 2.7 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OWF53023.1 - 0.88 9.7 4.0 2.2 8.4 0.2 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Glyco_transf_10 PF00852.19 OWF53024.1 - 2.7e-39 134.7 0.0 4.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF53024.1 - 2.2e-13 50.6 1.9 3.3e-13 50.1 0.6 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal zf-RING-like PF08746.11 OWF53024.1 - 4.1 7.8 6.3 0.53 10.6 1.8 1.8 2 0 0 2 2 2 0 RING-like domain Glyco_transf_10 PF00852.19 OWF53025.1 - 2.8e-52 177.0 4.1 3.7e-52 176.6 4.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF53025.1 - 1.2e-06 28.9 0.3 3.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal zf-RING-like PF08746.11 OWF53025.1 - 0.083 13.2 0.6 0.083 13.2 0.6 2.1 2 0 0 2 2 2 0 RING-like domain TIG PF01833.24 OWF53026.1 - 2.6e-150 488.9 157.1 3.1e-16 59.2 1.5 16.0 15 0 0 15 15 15 14 IPT/TIG domain G8 PF10162.9 OWF53026.1 - 2.3e-65 218.2 2.8 3.3e-36 124.1 0.4 3.3 2 0 0 2 2 2 2 G8 domain PA14 PF07691.12 OWF53026.1 - 8.7e-07 28.8 1.9 3.9e-06 26.7 1.2 2.5 2 0 0 2 2 2 1 PA14 domain GLEYA PF10528.9 OWF53026.1 - 0.00023 21.5 0.4 0.0035 17.7 0.5 3.1 2 0 0 2 2 2 1 GLEYA domain Cadherin_C_2 PF16492.5 OWF53026.1 - 0.12 13.1 2.5 0.13 13.0 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal CBM_14 PF01607.24 OWF53027.1 - 1.5e-24 85.9 17.7 4.6e-14 52.3 5.0 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Sulfotransfer_3 PF13469.6 OWF53028.1 - 1.1e-15 58.6 0.0 2.6e-15 57.4 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF53028.1 - 1.4e-14 54.2 0.4 4.3e-14 52.6 0.4 1.9 1 1 0 1 1 1 1 Sulfotransferase domain p450 PF00067.22 OWF53029.1 - 9.3e-85 285.1 0.1 1.1e-84 284.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF53030.1 - 4.8e-74 249.8 1.0 5.8e-74 249.5 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CamS PF07537.11 OWF53030.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor EGF_CA PF07645.15 OWF53031.1 - 4.6e-12 45.9 20.5 1.4e-07 31.6 7.8 9.4 11 0 0 11 11 11 2 Calcium-binding EGF domain cEGF PF12662.7 OWF53031.1 - 1.7e-10 40.7 59.6 0.00016 21.5 2.1 11.0 11 0 0 11 11 11 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF53031.1 - 1.4e-06 28.5 23.5 5.6e-05 23.3 8.3 8.5 9 0 0 9 9 9 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 OWF53031.1 - 0.0084 16.4 6.0 0.0084 16.4 6.0 9.7 11 0 0 11 11 11 3 EGF-like domain MAGUK_N_PEST PF10608.9 OWF53031.1 - 3.5 8.1 8.2 19 5.8 8.2 2.2 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Sel1 PF08238.12 OWF53033.1 - 3.3e-22 78.4 20.3 0.0037 17.9 0.0 9.8 9 0 0 9 9 9 6 Sel1 repeat Laminin_G_3 PF13385.6 OWF53033.1 - 0.002 18.3 0.1 0.0035 17.5 0.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF687 PF05095.12 OWF53033.1 - 0.15 10.5 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) TPR_17 PF13431.6 OWF53033.1 - 0.4 11.2 8.2 44 4.8 0.7 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-B_box PF00643.24 OWF53034.1 - 7.9e-06 25.9 5.7 1.8e-05 24.8 5.7 1.6 1 0 0 1 1 1 1 B-box zinc finger Rab5-bind PF09311.11 OWF53034.1 - 0.012 15.0 2.0 0.035 13.5 2.0 1.8 1 1 0 1 1 1 0 Rabaptin-like protein zf-UBR PF02207.20 OWF53034.1 - 0.014 15.5 4.3 0.043 14.0 4.3 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) SGL PF08450.12 OWF53034.1 - 0.015 14.9 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region RMMBL PF07521.12 OWF53034.1 - 0.015 15.2 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Not3 PF04065.15 OWF53034.1 - 0.017 14.5 3.6 0.022 14.2 2.1 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component LMBR1 PF04791.16 OWF53034.1 - 0.027 13.4 1.0 0.036 13.0 1.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CPDase PF07823.11 OWF53034.1 - 0.035 13.8 0.3 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein NHL PF01436.21 OWF53034.1 - 0.058 13.4 0.9 6.2 7.1 0.0 4.1 4 0 0 4 4 4 0 NHL repeat DUF2959 PF11172.8 OWF53034.1 - 0.063 13.4 1.3 0.13 12.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF4745 PF15923.5 OWF53034.1 - 0.068 13.2 0.3 8.1 6.4 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4745) Laminin_II PF06009.12 OWF53034.1 - 0.071 13.1 1.9 1.2 9.2 1.2 2.3 1 1 1 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 OWF53034.1 - 0.11 12.7 2.7 0.3 11.3 2.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OWF53034.1 - 0.15 12.1 0.4 1.4 8.9 0.2 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 OWF53034.1 - 0.18 11.8 3.3 0.41 10.7 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Prefoldin PF02996.17 OWF53034.1 - 0.29 11.1 6.7 11 5.9 2.4 3.7 2 1 2 4 4 4 0 Prefoldin subunit DUF1664 PF07889.12 OWF53034.1 - 0.37 10.8 3.3 4.3 7.4 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 OWF53034.1 - 2 8.3 5.5 3.2 7.6 2.7 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein EF-hand_6 PF13405.6 OWF53036.1 - 0.0038 17.0 1.0 1.5 8.9 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF53036.1 - 0.0086 16.5 0.5 3.2 8.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 OWF53036.1 - 0.021 14.7 0.1 0.045 13.6 0.0 1.5 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 OWF53036.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 OWF53036.1 - 0.19 11.4 2.0 2.4 7.9 0.4 2.3 2 0 0 2 2 2 0 EF hand I-set PF07679.16 OWF53039.1 - 3.2e-11 43.1 2.3 0.00027 20.9 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF53039.1 - 1e-06 29.3 0.7 0.051 14.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF53039.1 - 1.2e-05 25.4 0.4 0.018 15.2 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF53039.1 - 0.0017 18.7 1.7 1.2 9.5 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain CBM49 PF09478.10 OWF53039.1 - 0.042 14.2 0.1 0.84 10.0 0.0 2.6 2 1 0 2 2 2 0 Carbohydrate binding domain CBM49 ig PF00047.25 OWF53039.1 - 0.067 13.4 0.3 0.75 10.0 0.0 2.2 2 1 0 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 OWF53039.1 - 0.092 13.0 0.3 20 5.4 0.0 2.6 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 I-set PF07679.16 OWF53040.1 - 1e-21 76.8 0.0 0.0029 17.6 0.0 6.7 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF53040.1 - 1.3e-18 67.3 4.4 0.014 16.0 0.3 6.0 5 1 0 5 5 5 5 Immunoglobulin domain CUB PF00431.20 OWF53040.1 - 2.5e-14 53.6 0.0 7.2e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 CUB domain ig PF00047.25 OWF53040.1 - 1.6e-07 31.4 3.4 0.0033 17.6 0.5 4.2 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 OWF53040.1 - 9.8e-05 22.5 0.6 4.1 7.6 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF53040.1 - 0.00092 19.5 4.1 2.5 8.5 0.2 5.1 5 0 0 5 5 5 1 Immunoglobulin domain Ig_mannosidase PF17753.1 OWF53040.1 - 0.023 14.4 0.0 0.084 12.6 0.0 1.9 1 0 0 1 1 1 0 Ig-fold domain VirC2 PF07181.11 OWF53041.1 - 0.22 11.0 3.8 2 7.8 1.5 2.2 1 1 1 2 2 2 0 VirC2 protein Brix PF04427.18 OWF53042.1 - 2.6e-28 99.4 0.9 4.4e-28 98.7 0.9 1.4 1 0 0 1 1 1 1 Brix domain HEAT_PBS PF03130.16 OWF53043.1 - 5.7e-27 91.6 0.0 0.00029 21.2 0.0 6.7 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 OWF53043.1 - 2.8e-25 88.5 0.3 6.1e-11 42.6 0.0 4.0 2 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 OWF53043.1 - 1.4e-09 37.3 0.6 0.19 12.1 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat TAF6_C PF07571.13 OWF53043.1 - 0.032 14.6 0.0 1.4 9.3 0.0 3.3 3 1 1 4 4 4 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 OWF53043.1 - 0.14 12.2 0.0 11 6.3 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat F5_F8_type_C PF00754.25 OWF53044.1 - 4.1e-06 26.9 0.0 6.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain TMEM51 PF15345.6 OWF53044.1 - 0.0086 15.9 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 OAD_gamma PF04277.13 OWF53044.1 - 0.017 15.7 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF1179 PF06678.11 OWF53044.1 - 0.036 14.1 0.2 0.056 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Sarcoglycan_2 PF05510.13 OWF53044.1 - 0.061 12.1 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon SIT PF15330.6 OWF53044.1 - 0.064 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT ISK_Channel PF02060.15 OWF53044.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel EphA2_TM PF14575.6 OWF53044.1 - 0.15 12.9 0.0 0.33 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OWF53044.1 - 0.25 11.7 0.0 0.41 11.0 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 OWF53044.1 - 0.27 11.1 0.0 0.43 10.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 OWF53044.1 - 5.9 7.7 5.3 2.1e+02 2.7 5.3 2.8 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal FHA PF00498.26 OWF53045.1 - 2.9e-14 53.2 0.1 5.9e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain MCR_beta_N PF02783.15 OWF53046.1 - 0.092 12.4 0.0 19 4.8 0.0 2.9 1 1 1 3 3 3 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain NADHdh-2_N PF12155.8 OWF53046.1 - 0.43 11.0 15.5 2.6 8.5 0.1 3.8 1 1 2 3 3 3 0 NADH dehydrogenase subunit 2 N-terminal Ion_trans PF00520.31 OWF53047.1 - 4.4e-37 127.6 18.8 5.6e-37 127.3 18.8 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF53047.1 - 4.7e-25 87.8 0.0 8.9e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF53047.1 - 1.2e-09 38.0 6.3 1.2e-09 38.0 6.3 2.3 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 OWF53047.1 - 0.018 15.2 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF4293 PF14126.6 OWF53047.1 - 5.7 7.2 13.2 19 5.4 5.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Ion_trans PF00520.31 OWF53048.1 - 1.7e-37 129.0 18.5 2.6e-37 128.4 18.5 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF53048.1 - 1.7e-09 37.5 5.8 1.7e-09 37.5 5.8 2.3 3 0 0 3 3 3 1 Ion channel BTB_2 PF02214.22 OWF53048.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain LRR19-TM PF15176.6 OWF53048.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TIR_2 PF13676.6 OWF53049.1 - 6.4e-07 30.0 0.1 1.4e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 TIR domain DUF2417 PF10329.9 OWF53051.1 - 0.0074 15.7 0.4 0.016 14.7 0.4 1.5 1 0 0 1 1 1 1 Region of unknown function (DUF2417) WW PF00397.26 OWF53054.1 - 1.4e-09 37.8 21.0 1.6 8.9 0.6 8.1 1 1 11 12 12 12 9 WW domain DUF5132 PF17195.4 OWF53054.1 - 0.00029 20.9 10.4 39 4.5 0.1 7.1 4 2 4 9 9 9 0 Protein of unknown function (DUF5132) DUF150 PF02576.17 OWF53054.1 - 0.0025 18.2 3.9 55 4.3 0.1 5.3 1 1 6 7 7 7 0 RimP N-terminal domain DUF1943 PF09172.11 OWF53054.1 - 0.0031 16.8 5.9 0.075 12.3 1.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1943) DUF2971 PF11185.8 OWF53054.1 - 0.0042 18.2 5.0 9 7.5 0.4 5.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2971) EMG1 PF03587.14 OWF53054.1 - 0.0087 15.7 3.4 22 4.6 0.1 4.1 1 1 3 4 4 4 0 EMG1/NEP1 methyltransferase DUF5522 PF17653.1 OWF53054.1 - 0.022 14.7 7.4 27 4.8 0.1 5.9 1 1 7 8 8 8 0 Family of unknown function (DUF5522) Lactococcin PF04369.13 OWF53054.1 - 0.057 13.6 7.3 14 5.9 0.3 4.1 1 1 3 4 4 4 0 Lactococcin-like family Flagellin_IN PF07196.13 OWF53054.1 - 1.1 9.5 17.4 40 4.5 0.5 6.6 2 1 4 6 6 6 0 Flagellin hook IN motif WD40_3 PF15911.5 OWF53054.1 - 3.4 7.8 12.9 39 4.4 0.2 4.6 1 1 4 5 5 5 0 WD domain, G-beta repeat Corona_NS4 PF03905.13 OWF53054.1 - 7.5 6.6 33.7 18 5.4 1.2 7.9 1 1 5 6 6 6 0 Coronavirus non-structural protein NS4 Lectin_C PF00059.21 OWF53055.1 - 6.2e-17 62.3 8.6 7.8e-17 62.0 8.6 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF53055.1 - 0.0046 16.6 1.2 0.0059 16.3 1.2 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF53055.1 - 0.17 11.2 0.2 0.17 11.2 0.2 2.0 2 1 1 3 3 3 0 Chordopoxvirus A33R protein Ets PF00178.22 OWF53056.1 - 1.3e-31 108.9 0.3 4.3e-31 107.2 0.4 1.9 2 0 0 2 2 2 1 Ets-domain Ets PF00178.22 OWF53058.1 - 2.3e-24 85.7 0.1 4.5e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 OWF53058.1 - 2.4e-12 46.7 1.4 8.3e-12 44.9 0.6 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain CBM53 PF16760.5 OWF53058.1 - 0.083 13.5 1.5 0.97 10.1 1.1 2.4 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) Methyltransf_21 PF05050.12 OWF53059.1 - 0.00029 20.9 1.3 0.0034 17.4 1.3 2.1 1 1 0 1 1 1 1 Methyltransferase FkbM domain TMEM18 PF14770.6 OWF53060.1 - 1.4e-41 141.1 6.9 1.7e-41 140.9 6.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 IQ PF00612.27 OWF53061.1 - 0.001 18.6 0.1 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Archease PF01951.16 OWF53062.1 - 1.3e-40 138.8 0.4 1.5e-40 138.6 0.4 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) VWC PF00093.18 OWF53063.1 - 0.00048 20.4 5.8 0.00083 19.6 5.8 1.6 1 1 0 1 1 1 1 von Willebrand factor type C domain PSP94 PF05825.11 OWF53063.1 - 0.068 13.7 4.9 0.083 13.5 4.9 1.3 1 1 0 1 1 1 0 Beta-microseminoprotein (PSP-94) DUF1496 PF07383.12 OWF53063.1 - 0.13 11.8 0.4 0.13 11.8 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1496) COPIIcoated_ERV PF07970.12 OWF53065.1 - 1.1e-94 316.5 4.7 1.4e-94 316.0 4.7 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OWF53065.1 - 1.5e-30 105.4 0.0 3.3e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) OATP PF03137.20 OWF53066.1 - 6.1e-153 510.0 20.7 6.1e-153 510.0 20.7 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF53066.1 - 6.6e-25 87.8 39.6 4.8e-21 75.1 38.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF53066.1 - 7.6e-08 32.4 12.3 1.8e-07 31.2 12.3 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF53066.1 - 0.014 15.4 11.7 0.033 14.2 11.7 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain OATP PF03137.20 OWF53067.1 - 1.9e-161 538.0 11.3 2.4e-161 537.7 11.3 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF53067.1 - 1.6e-19 70.1 29.0 1.6e-18 66.8 20.4 3.1 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF53067.1 - 1.6e-08 34.5 15.6 1.6e-08 34.5 15.6 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain MFS_1_like PF12832.7 OWF53067.1 - 0.44 9.4 10.2 0.11 11.3 0.6 3.4 4 0 0 4 4 4 0 MFS_1 like family UCR_14kD PF02271.16 OWF53068.1 - 8.7e-13 48.1 0.1 1.2e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit IGPD PF00475.18 OWF53068.1 - 0.05 13.9 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Aldose_epim PF01263.20 OWF53069.1 - 0.61 9.3 16.6 0.35 10.1 2.0 4.4 1 1 2 4 4 4 0 Aldose 1-epimerase SSrecog PF03531.14 OWF53069.1 - 2.3 8.2 35.3 6.9 6.7 3.0 7.0 2 2 5 7 7 7 0 Structure-specific recognition protein (SSRP1) Kringle PF00051.18 OWF53070.1 - 5.7e-15 55.4 10.7 7.2e-15 55.1 10.7 1.2 1 0 0 1 1 1 1 Kringle domain Toxin_18 PF08087.11 OWF53070.1 - 0.0072 16.3 1.6 0.017 15.1 0.9 1.9 2 0 0 2 2 2 1 Conotoxin O-superfamily Glyco_hydro_1 PF00232.18 OWF53071.1 - 0 1113.6 19.6 1.7e-171 570.6 7.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 OWF53071.1 - 0.00011 22.6 0.1 0.18 12.2 0.0 3.7 4 0 0 4 4 4 1 GDSL-like Lipase/Acylhydrolase family Cellulase PF00150.18 OWF53071.1 - 0.00018 21.0 2.9 0.2 11.0 0.1 3.2 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) DUF3258 PF11646.8 OWF53071.1 - 0.001 19.2 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function DUF3258 Glyco_hydro_1 PF00232.18 OWF53073.1 - 1.2e-112 376.6 6.5 1.4e-64 218.2 1.3 3.9 2 1 1 3 3 3 3 Glycosyl hydrolase family 1 GshA PF08886.11 OWF53073.1 - 0.17 10.4 0.0 9.5 4.7 0.0 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase INTS5_C PF14838.6 OWF53074.1 - 3.9 6.0 53.3 0.31 9.6 3.5 6.0 1 1 5 6 6 6 0 Integrator complex subunit 5 C-terminus cNMP_binding PF00027.29 OWF53075.1 - 6.5e-19 67.8 0.0 1.2e-09 38.1 0.0 4.3 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain OMPdecase PF00215.24 OWF53076.1 - 2.1e-79 266.2 0.0 3.3e-79 265.6 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 OWF53076.1 - 1.4e-10 40.9 0.1 4.2e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RNA_pol_Rpb4 PF03874.16 OWF53077.1 - 7e-26 91.0 7.7 8.8e-26 90.6 7.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rop PF01815.16 OWF53077.1 - 0.021 14.7 0.4 0.049 13.5 0.1 1.8 2 0 0 2 2 2 0 Rop protein VWA PF00092.28 OWF53078.1 - 2.2e-07 31.3 0.0 3.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OWF53079.1 - 1.2e-08 35.4 0.0 1.3e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Myb_DNA-bind_4 PF13837.6 OWF53079.1 - 0.038 14.4 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain YTH PF04146.15 OWF53080.1 - 8.4e-21 74.6 0.1 1.3e-20 74.0 0.1 1.3 1 0 0 1 1 1 1 YT521-B-like domain RlaP PF10127.9 OWF53080.1 - 4.4e-15 55.9 0.0 7.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 OWF53080.1 - 9.8e-05 22.6 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OWF53080.1 - 0.012 15.7 0.0 0.044 13.9 0.0 2.1 1 1 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Prok-RING_2 PF14445.6 OWF53080.1 - 0.068 13.3 0.3 0.23 11.6 0.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 DUF2045 PF09741.9 OWF53081.1 - 2.4e-96 321.6 0.7 3.7e-96 321.0 0.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) PDDEXK_10 PF07788.11 OWF53081.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF1179 PF06678.11 OWF53081.1 - 0.11 12.5 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) AMP-binding_C PF13193.6 OWF53082.1 - 1.9e-18 67.2 2.5 3.4e-18 66.4 2.5 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF53082.1 - 4.7e-14 51.8 0.1 5.9e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 OWF53083.1 - 1.4e-48 165.6 0.0 1.7e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OWF53083.1 - 1.5e-22 79.3 1.9 2.8e-22 78.4 1.9 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus LRR_12 PF18837.1 OWF53084.1 - 2.5 7.8 11.4 56 3.5 0.1 5.4 3 3 3 6 6 6 0 Leucine-rich repeat Isochorismatase PF00857.20 OWF53085.1 - 5.6e-29 101.6 0.1 9.2e-29 100.8 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family G6PD_C PF02781.16 OWF53086.1 - 9.1e-57 192.4 0.0 1.4e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Glucosamine_iso PF01182.20 OWF53086.1 - 1.5e-51 175.5 0.0 2.3e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_N PF00479.22 OWF53086.1 - 1.2e-33 117.2 0.0 2.4e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain HNOBA PF07701.14 OWF53088.1 - 4.3e-72 242.1 1.8 4.3e-72 242.1 1.8 2.1 2 0 0 2 2 2 1 Heme NO binding associated Guanylate_cyc PF00211.20 OWF53088.1 - 1.3e-62 210.7 1.7 5.8e-62 208.6 1.7 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 OWF53088.1 - 1.6e-53 181.0 0.1 2.7e-53 180.3 0.1 1.4 1 0 0 1 1 1 1 Haem-NO-binding MCLC PF05934.11 OWF53088.1 - 7.9 5.1 8.8 14 4.3 8.8 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) GAD PF02938.14 OWF53089.1 - 7.7e-06 26.1 0.4 65 3.9 0.0 6.4 1 1 4 7 7 7 0 GAD domain Reo_sigmaC PF04582.12 OWF53089.1 - 0.00013 22.3 17.4 0.22 11.8 1.0 4.5 1 1 5 6 6 6 5 Reovirus sigma C capsid protein C-terminal domain OB_RNB PF08206.11 OWF53089.1 - 0.0013 18.4 2.6 26 4.6 0.0 5.2 1 1 6 7 7 7 0 Ribonuclease B OB domain DUF4261 PF14080.6 OWF53089.1 - 0.0014 18.7 3.8 15 5.8 0.0 5.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4261) DUF2000 PF09391.10 OWF53089.1 - 0.011 15.6 1.1 6.6 6.7 0.1 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) AvrM_N PF18247.1 OWF53089.1 - 0.012 15.5 6.9 1.5 8.8 0.2 4.0 3 2 2 5 5 5 0 Flax-rust effector AvrM N-terminal domain DUF4537 PF15057.6 OWF53089.1 - 0.017 15.1 9.0 2.7 8.1 0.7 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4537) Ribosomal_S18 PF01084.20 OWF53089.1 - 0.021 15.0 5.1 39 4.6 0.1 5.4 5 1 0 6 6 6 0 Ribosomal protein S18 DUF452 PF04301.13 OWF53089.1 - 0.025 14.1 1.9 3.6 7.1 0.2 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF452) DUF2345 PF10106.9 OWF53089.1 - 0.052 13.4 15.3 0.11 12.3 5.3 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF2190 PF09956.9 OWF53089.1 - 0.17 12.4 4.7 10 6.7 2.7 4.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2190) DUF370 PF04025.12 OWF53089.1 - 0.22 11.6 18.7 3.1 8.0 0.4 6.4 1 1 6 7 7 7 0 Domain of unknown function (DUF370) AAA_lid_6 PF17866.1 OWF53089.1 - 8.6 6.6 7.8 62 3.9 0.1 4.4 6 0 0 6 6 6 0 AAA lid domain Reo_sigmaC PF04582.12 OWF53090.1 - 0.003 17.8 10.9 0.12 12.6 0.4 4.0 1 1 4 5 5 5 2 Reovirus sigma C capsid protein C-terminal domain CG-1 PF03859.16 OWF53090.1 - 0.024 14.4 1.6 1 9.2 0.1 2.3 1 1 1 2 2 2 0 CG-1 domain OB_RNB PF08206.11 OWF53090.1 - 0.033 13.9 1.3 25 4.6 0.0 4.1 2 1 2 4 4 4 0 Ribonuclease B OB domain DUF4261 PF14080.6 OWF53090.1 - 0.068 13.3 1.7 53 4.0 0.0 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4261) DUF2345 PF10106.9 OWF53090.1 - 0.14 12.0 10.4 1.7 8.5 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF4537 PF15057.6 OWF53090.1 - 0.21 11.6 4.0 14 5.7 0.1 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4537) DUF4479 PF14794.6 OWF53090.1 - 0.23 11.4 4.6 0.94 9.4 0.1 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4479) Hexapep_loop PF18776.1 OWF53090.1 - 0.36 10.5 1.6 68 3.2 0.0 3.3 3 0 0 3 3 3 0 Hexapeptide repeat including loop AvrM_N PF18247.1 OWF53090.1 - 0.37 10.8 1.4 6 6.9 0.2 2.9 1 1 3 4 4 4 0 Flax-rust effector AvrM N-terminal domain Ribosomal_S18 PF01084.20 OWF53090.1 - 8.9 6.6 6.5 41 4.5 0.2 4.0 4 1 2 6 6 6 0 Ribosomal protein S18 SIT PF15330.6 OWF53091.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Laminin_EGF PF00053.24 OWF53091.1 - 0.011 15.8 62.7 0.044 13.9 19.5 5.1 1 1 3 4 4 4 0 Laminin EGF domain EphA2_TM PF14575.6 OWF53091.1 - 0.034 15.0 0.1 0.14 13.1 0.1 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5367 PF17329.2 OWF53092.1 - 0.053 13.6 0.1 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5367) MaoC_dehydrat_N PF13452.6 OWF53092.1 - 0.063 13.4 0.2 0.17 12.1 0.2 1.7 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase Adeno_E3_CR2 PF02439.15 OWF53092.1 - 0.091 12.5 7.8 0.2 11.5 7.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 2OG-FeII_Oxy PF03171.20 OWF53093.1 - 2.8e-14 53.4 0.0 4.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OWF53093.1 - 9.8e-10 39.2 0.0 1.5e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Rdx PF10262.9 OWF53094.1 - 0.15 12.3 1.3 0.3 11.3 1.3 1.4 1 0 0 1 1 1 0 Rdx family ODV-E18 PF10717.9 OWF53094.1 - 0.2 11.6 1.5 0.25 11.3 0.2 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ferritin PF00210.24 OWF53095.1 - 6.9e-39 133.0 0.1 7.9e-39 132.8 0.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 OWF53095.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Rubrerythrin Kinesin PF00225.23 OWF53096.1 - 4.3e-85 285.6 0.1 4.3e-85 285.6 0.1 2.4 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OWF53096.1 - 7.5e-21 74.6 0.0 7.5e-21 74.6 0.0 2.3 2 1 0 2 2 2 1 Microtubule binding Peptidase_M54 PF07998.11 OWF53097.1 - 2.3e-08 34.2 0.5 6.4e-08 32.8 0.5 1.8 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M57 PF12388.8 OWF53097.1 - 0.054 13.1 0.1 0.087 12.4 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_C1 PF00112.23 OWF53098.1 - 1.9e-55 188.3 0.4 2.7e-55 187.8 0.1 1.3 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF53098.1 - 1e-05 25.9 0.3 1.7e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF53098.1 - 0.0013 17.6 0.3 0.002 17.0 0.3 1.2 1 0 0 1 1 1 1 Peptidase C1-like family Mlo PF03094.15 OWF53098.1 - 0.16 10.3 0.3 0.21 9.9 0.3 1.1 1 0 0 1 1 1 0 Mlo family 7tm_1 PF00001.21 OWF53099.1 - 1.2e-25 90.3 12.5 1.6e-25 89.9 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF53099.1 - 2.6e-05 24.0 8.7 5.5e-05 22.9 8.7 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF53099.1 - 8.1e-05 22.1 8.1 0.00017 21.1 8.1 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.15 OWF53099.1 - 8.3e-05 22.6 2.5 8.3e-05 22.6 2.5 2.0 2 0 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa Pkinase_Tyr PF07714.17 OWF53099.1 - 0.00048 19.5 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FA_desaturase PF00487.24 OWF53099.1 - 0.01 15.7 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Pkinase PF00069.25 OWF53099.1 - 0.035 13.5 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain 7TM_GPCR_Srbc PF10316.9 OWF53099.1 - 0.11 12.0 8.7 0.025 14.1 4.3 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc Vma12 PF11712.8 OWF53099.1 - 2.3 8.3 4.7 1.3 9.1 1.7 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ASC PF00858.24 OWF53100.1 - 8.7e-68 229.3 8.0 1e-67 229.1 8.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel HTH_23 PF13384.6 OWF53103.1 - 5.2e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.26 OWF53103.1 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_7 PF02796.15 OWF53103.1 - 0.0015 18.5 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 OWF53103.1 - 0.0059 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 OWF53103.1 - 0.011 15.8 0.7 0.042 14.0 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 OWF53103.1 - 0.02 14.9 1.0 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix HTH_11 PF08279.12 OWF53103.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 OWF53103.1 - 0.049 13.4 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain SAM_1 PF00536.30 OWF53103.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HTH_30 PF13556.6 OWF53103.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Peptidase_M14 PF00246.24 OWF53104.1 - 3.1e-231 765.7 0.7 1.3e-80 271.3 0.2 5.1 4 1 1 5 5 5 5 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 OWF53104.1 - 8.6e-48 160.5 5.8 3.7e-12 46.3 0.6 4.5 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OWF53104.1 - 6.2e-35 119.1 4.4 6e-09 35.8 0.1 4.5 4 0 0 4 4 4 4 CarboxypepD_reg-like domain AstE_AspA PF04952.14 OWF53104.1 - 3.5e-14 52.6 8.6 0.0015 17.6 0.5 4.5 4 0 0 4 4 4 4 Succinylglutamate desuccinylase / Aspartoacylase family PEGA PF08308.11 OWF53104.1 - 5.1e-13 48.7 3.6 0.0049 16.7 0.0 5.3 5 0 0 5 5 5 3 PEGA domain CooC_C PF15976.5 OWF53104.1 - 0.0039 17.2 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 CS1-pili formation C-terminal DUF2119 PF09892.9 OWF53104.1 - 0.0044 16.4 1.9 1.9 7.8 0.0 3.7 4 0 0 4 4 4 2 Uncharacterized protein conserved in archaea (DUF2119) Wzt_C PF14524.6 OWF53104.1 - 0.019 15.0 0.3 2 8.5 0.0 3.6 4 0 0 4 4 4 0 Wzt C-terminal domain DUF2817 PF10994.8 OWF53104.1 - 0.071 12.5 5.5 0.15 11.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2817) DUF1533 PF07550.11 OWF53104.1 - 0.078 12.9 0.0 4.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1533) HLH PF00010.26 OWF53105.1 - 3.6e-14 52.4 0.6 2.6e-13 49.7 0.1 2.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain JIP_LZII PF16471.5 OWF53105.1 - 2.2 8.5 14.7 0.22 11.7 0.6 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Thioredoxin_13 PF18401.1 OWF53106.1 - 0.025 14.5 0.0 0.07 13.1 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain WD40 PF00400.32 OWF53107.1 - 1.3e-22 79.7 11.7 7.8e-05 23.4 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat MAP17 PF15807.5 OWF53107.1 - 0.024 14.8 0.7 0.048 13.9 0.7 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM51 PF15345.6 OWF53107.1 - 0.044 13.6 0.3 0.069 13.0 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 PD40 PF07676.12 OWF53107.1 - 0.05 13.6 1.5 42 4.2 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Shisa PF13908.6 OWF53107.1 - 0.084 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF53107.1 - 0.11 13.3 0.1 0.23 12.3 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DNA_pol_delta_4 PF04081.13 OWF53108.1 - 3.2e-20 72.8 0.0 3.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF913 PF06025.12 OWF53109.1 - 0.24 10.3 2.7 0.19 10.6 1.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DSPc PF00782.20 OWF53110.1 - 5.3e-28 97.5 0.0 8.8e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 OWF53110.1 - 8.6e-08 32.7 0.0 3.2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Init_tRNA_PT PF04179.12 OWF53110.1 - 0.0026 18.0 0.0 0.0079 16.5 0.0 1.7 1 1 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 OWF53110.1 - 0.0036 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ldh_1_C PF02866.18 OWF53111.1 - 1.6e-48 164.8 0.2 4.1e-48 163.5 0.3 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OWF53111.1 - 1.2e-43 148.6 0.0 2e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OWF53111.1 - 0.0018 17.3 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OWF53111.1 - 0.0055 17.1 0.0 0.016 15.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OWF53111.1 - 0.015 14.7 0.3 0.15 11.3 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 OWF53111.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus EST1_DNA_bind PF10373.9 OWF53112.1 - 1.1e-62 212.0 1.2 4.4e-62 210.1 0.0 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 OWF53112.1 - 1e-24 87.3 0.7 1e-24 87.3 0.7 3.1 4 0 0 4 4 4 1 PIN domain EST1 PF10374.9 OWF53112.1 - 1.4e-18 67.9 0.8 1.4e-18 67.9 0.8 2.8 2 0 0 2 2 2 1 Telomerase activating protein Est1 PIN_9 PF18477.1 OWF53112.1 - 1.6 9.1 7.0 1.2 9.5 0.0 3.7 2 1 1 3 3 3 0 PIN like domain GIDA PF01134.22 OWF53113.1 - 7.5e-147 489.5 0.0 1.1e-146 489.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 OWF53113.1 - 5.5e-66 222.7 0.4 8.2e-66 222.2 0.4 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 OWF53113.1 - 2.8e-06 27.0 1.2 9.9e-06 25.2 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF53113.1 - 0.00091 18.5 0.7 0.0021 17.3 0.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF53113.1 - 0.0029 18.1 0.1 0.0081 16.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF53113.1 - 0.003 16.7 1.8 0.0033 16.6 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OWF53113.1 - 0.021 13.5 3.3 0.081 11.6 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 OWF53113.1 - 0.023 14.0 0.0 0.095 12.0 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain bZIP_1 PF00170.21 OWF53114.1 - 0.019 15.0 3.4 0.019 15.0 3.4 3.7 4 0 0 4 4 4 0 bZIP transcription factor CheZ PF04344.13 OWF53114.1 - 0.022 14.7 9.6 0.07 13.0 6.2 2.7 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ Laminin_I PF06008.14 OWF53114.1 - 0.13 12.0 16.4 0.16 11.7 10.8 2.8 2 1 0 2 2 2 0 Laminin Domain I JIP_LZII PF16471.5 OWF53114.1 - 2.8 8.2 12.1 0.053 13.7 3.7 2.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Laminin_II PF06009.12 OWF53114.1 - 4.8 7.2 16.6 0.057 13.4 6.5 2.8 3 1 1 4 4 4 0 Laminin Domain II YabA PF06156.13 OWF53114.1 - 9 7.0 12.9 0.92 10.2 5.8 3.0 3 0 0 3 3 3 0 Initiation control protein YabA Vps4_C PF09336.10 OWF53115.1 - 0.02 14.9 1.1 17 5.5 0.0 3.7 2 2 3 5 5 5 0 Vps4 C terminal oligomerisation domain CYYR1 PF10873.8 OWF53115.1 - 2.1 8.8 9.9 2.4 8.6 2.6 2.1 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 7tm_1 PF00001.21 OWF53116.1 - 6.7e-14 51.8 16.0 6.7e-14 51.8 16.0 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) FAM176 PF14851.6 OWF53116.1 - 3.8 7.2 5.9 5.1 6.8 0.1 2.6 2 0 0 2 2 2 0 FAM176 family DEP PF00610.21 OWF53117.1 - 3.3e-22 78.3 0.6 8.9e-22 76.9 0.6 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) cNMP_binding PF00027.29 OWF53117.1 - 2.7e-13 49.8 0.0 4.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Globin PF00042.22 OWF53118.1 - 8.2e-12 45.7 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Globin DUF3492 PF11997.8 OWF53118.1 - 0.0026 17.5 0.1 0.0043 16.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) DSPc PF00782.20 OWF53119.1 - 5.4e-43 146.0 0.1 1.1e-42 145.0 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 OWF53119.1 - 3.5e-14 53.2 0.0 7.7e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 OWF53119.1 - 1.4e-08 35.0 0.0 2.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OWF53119.1 - 0.00015 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 OWF53119.1 - 0.0027 18.0 0.0 0.007 16.6 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain CDKN3 PF05706.12 OWF53119.1 - 0.022 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Myotub-related PF06602.14 OWF53119.1 - 0.036 13.0 0.0 0.075 12.0 0.0 1.5 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Cys_Met_Meta_PP PF01053.20 OWF53119.1 - 0.045 12.3 0.0 0.076 11.5 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Kelch_1 PF01344.25 OWF53120.1 - 5.5e-38 128.3 10.9 7.3e-09 35.1 0.4 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 OWF53120.1 - 8.6e-23 79.8 6.6 0.00016 21.9 0.1 5.3 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 OWF53120.1 - 2.5e-18 65.8 7.7 3.7e-06 26.8 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF53120.1 - 5.9e-18 64.4 2.2 0.00035 20.5 0.1 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 OWF53120.1 - 5e-15 55.4 4.8 0.00095 19.4 0.2 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF53120.1 - 8.8e-15 54.0 10.2 2.7e-06 27.1 0.1 5.4 5 1 0 5 5 5 4 Kelch motif Frtz PF11768.8 OWF53121.1 - 2.2e-188 627.0 0.0 2.6e-188 626.7 0.0 1.0 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz TFIIA PF03153.13 OWF53124.1 - 6.6e-65 220.7 31.6 1.6e-38 133.8 18.9 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 OWF53124.1 - 0.0036 15.5 11.7 0.0048 15.1 11.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 OWF53124.1 - 0.011 14.1 1.8 0.013 13.9 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OWF53124.1 - 0.12 10.5 10.3 0.15 10.2 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.12 OWF53124.1 - 0.28 9.0 4.8 0.35 8.7 4.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF2574 PF10836.8 OWF53124.1 - 0.41 10.6 2.1 0.84 9.6 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) SURF2 PF05477.11 OWF53124.1 - 0.78 9.4 6.1 1.2 8.8 6.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Pox_Ag35 PF03286.14 OWF53124.1 - 0.86 9.4 8.2 1.3 8.7 8.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 OWF53124.1 - 1 9.0 4.3 2 8.1 4.3 1.5 1 0 0 1 1 1 0 FAM176 family Roughex PF06020.11 OWF53124.1 - 1.7 7.6 6.9 2.4 7.2 6.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Cu_amine_oxidN1 PF07833.11 OWF53125.1 - 2.5e-05 24.7 7.6 5.6e+02 1.1 7.6 6.2 1 1 0 1 1 1 0 Copper amine oxidase N-terminal domain TFIIIC_delta PF12657.7 OWF53126.1 - 0.03 14.3 0.4 0.24 11.3 0.4 2.1 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term HAD PF12710.7 OWF53126.1 - 0.3 11.5 1.5 2.8 8.3 0.2 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase 7tm_1 PF00001.21 OWF53127.1 - 4.1e-76 255.8 0.7 8.1e-76 254.8 0.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF53127.1 - 3.2e-13 49.7 13.0 3.1e-09 36.6 4.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF53127.1 - 6.5e-08 32.6 8.6 8.1e-06 25.8 2.7 2.5 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF53127.1 - 9e-07 28.8 9.7 9e-07 28.8 9.7 2.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GWT1 PF06423.12 OWF53127.1 - 0.33 11.1 6.7 0.096 12.8 0.7 2.6 2 0 0 2 2 2 0 GWT1 S1 PF00575.23 OWF53128.1 - 7.6e-19 67.8 0.1 1.4e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 OWF53128.1 - 3.5e-15 56.1 0.1 6.1e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 OWF53128.1 - 2.2e-05 24.7 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SRP14 PF02290.15 OWF53129.1 - 3.4e-28 97.8 0.0 5.3e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF3509 PF12021.8 OWF53129.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Mre11_DNA_bind PF04152.14 OWF53129.1 - 0.057 13.7 0.2 0.066 13.5 0.2 1.1 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain Kinesin PF00225.23 OWF53130.1 - 5.7e-110 367.4 0.2 5.7e-110 367.4 0.2 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF53130.1 - 3.7e-24 85.4 0.0 3.7e-24 85.4 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding PX PF00787.24 OWF53130.1 - 1.6e-13 50.7 3.1 3.7e-13 49.4 0.7 2.9 3 0 0 3 3 3 1 PX domain Kinesin_assoc PF16183.5 OWF53130.1 - 2.8e-07 30.9 3.9 4.6e-05 23.7 0.7 6.2 3 2 3 6 6 6 2 Kinesin-associated FHA PF00498.26 OWF53130.1 - 0.00023 21.4 0.0 0.002 18.4 0.0 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OWF53130.1 - 0.008 16.5 0.0 0.051 13.9 0.0 2.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C4pol PF14260.6 OWF53131.1 - 0.003 18.0 1.2 0.31 11.6 0.1 3.1 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta 14-3-3 PF00244.20 OWF53131.1 - 0.016 14.7 0.7 0.034 13.7 0.3 1.5 1 1 0 1 1 1 0 14-3-3 protein RNase_T PF00929.24 OWF53131.1 - 0.048 14.2 0.4 0.064 13.8 0.4 1.3 1 0 0 1 1 1 0 Exonuclease TrbC_Ftype PF09673.10 OWF53131.1 - 0.11 12.6 0.0 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein PfkB PF00294.24 OWF53132.1 - 9.1e-66 222.2 3.4 1e-65 222.0 3.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OWF53132.1 - 3.6e-06 26.5 0.3 9.4e-06 25.2 0.0 1.7 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase Aldolase PF01081.19 OWF53132.1 - 0.024 14.1 2.4 0.14 11.6 0.2 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase IgGFc_binding PF17517.2 OWF53133.1 - 6.8e-40 137.2 2.8 1.2e-39 136.4 2.8 1.4 1 0 0 1 1 1 1 IgGFc binding protein DUF5528 PF17666.1 OWF53133.1 - 0.025 14.5 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5528) TMEM154 PF15102.6 OWF53134.1 - 0.019 14.9 7.0 0.072 13.0 7.0 2.0 1 1 0 1 1 1 0 TMEM154 protein family EssA PF10661.9 OWF53134.1 - 0.079 12.8 0.4 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Imm7 PF15585.6 OWF53134.1 - 0.14 12.5 0.3 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 7 Lectin_C PF00059.21 OWF53134.1 - 0.22 12.3 9.4 7.4 7.4 4.1 3.0 2 1 0 2 2 2 0 Lectin C-type domain TMEM154 PF15102.6 OWF53135.1 - 1.7e-05 24.8 1.4 3e-05 23.9 1.4 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4064 PF13273.6 OWF53135.1 - 0.025 14.8 1.2 0.37 11.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1180 PF06679.12 OWF53135.1 - 0.063 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Stevor PF17410.2 OWF53135.1 - 0.087 12.4 0.4 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Mid2 PF04478.12 OWF53135.1 - 0.095 12.5 4.3 0.22 11.4 4.3 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2207 PF09972.9 OWF53135.1 - 0.3 9.8 1.3 0.27 10.0 0.0 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 OWF53135.1 - 0.98 9.5 6.5 0.088 12.9 1.6 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 OWF53135.1 - 1.7 9.0 5.8 0.14 12.5 0.4 1.9 2 0 0 2 2 2 0 Orf78 (ac78) Pro_isomerase PF00160.21 OWF53136.1 - 5e-46 156.9 0.2 5e-46 156.9 0.2 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 OWF53136.1 - 7.8e-05 22.4 28.3 7.8e-05 22.4 28.3 8.6 5 3 3 8 8 8 1 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 OWF53137.1 - 3.8e-16 59.4 0.2 2.9e-08 34.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF53137.1 - 2.6e-12 46.6 0.3 4.6e-05 23.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OWF53137.1 - 6.6e-12 45.7 0.1 2.4e-05 24.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF53137.1 - 2.7e-11 42.6 0.0 0.00018 21.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.18 OWF53137.1 - 4.4e-09 36.3 14.2 8.1e-09 35.4 14.2 1.4 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 OWF53137.1 - 1.2e-08 35.1 0.1 0.029 14.7 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF615 PF04751.14 OWF53137.1 - 0.011 15.7 0.1 0.011 15.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF615) Pkinase PF00069.25 OWF53138.1 - 3e-75 253.0 0.0 3.4e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF53138.1 - 1.1e-34 119.9 0.0 1.5e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF53138.1 - 9.4e-05 21.5 0.0 0.00086 18.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF53138.1 - 0.00036 20.5 0.2 0.026 14.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF53138.1 - 0.00036 19.9 0.1 0.0072 15.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OWF53138.1 - 0.0049 16.3 0.1 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OWF53138.1 - 0.042 12.9 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Collagen PF01391.18 OWF53139.1 - 9.1e-25 86.2 70.4 2e-09 37.0 19.9 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) YabA PF06156.13 OWF53139.1 - 0.063 13.9 0.3 0.089 13.4 0.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA LidA_Long_CC PF18641.1 OWF53139.1 - 0.097 12.7 0.5 0.15 12.1 0.5 1.2 1 0 0 1 1 1 0 LidA long coiled-coil domain zf-C2H2 PF00096.26 OWF53140.1 - 3.3e-19 68.2 27.6 0.00043 20.6 0.6 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF53140.1 - 5.7e-12 45.5 26.5 9.7e-06 25.8 0.9 5.4 5 0 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 OWF53140.1 - 9.7e-06 26.1 17.0 0.17 12.6 0.3 5.4 1 1 2 4 4 4 3 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OWF53140.1 - 6.2e-05 23.5 26.1 0.044 14.6 0.5 5.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OWF53140.1 - 0.14 12.3 17.6 0.13 12.4 3.3 3.2 2 1 2 4 4 4 0 Aberrant zinc-finger zf_ZIC PF18366.1 OWF53140.1 - 0.9 9.7 8.7 5.9 7.1 0.9 3.8 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 OWF53140.1 - 1.6 8.8 4.6 2 8.5 1.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PcF PF09461.10 OWF53140.1 - 1.8 9.0 6.2 58 4.2 0.1 3.9 2 1 1 3 3 3 0 Phytotoxin PcF protein zf-C2H2_3rep PF18868.1 OWF53140.1 - 3.6 8.3 9.8 0.65 10.7 0.9 3.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 OWF53140.1 - 4.6 7.6 14.6 0.46 10.8 1.5 3.6 2 1 0 3 3 3 0 C2H2-type zinc ribbon BHD_1 PF10403.9 OWF53141.1 - 0.064 13.1 7.6 2.5 8.0 0.1 4.6 3 2 1 4 4 4 0 Rad4 beta-hairpin domain 1 zf-C2H2_6 PF13912.6 OWF53141.1 - 2 8.5 22.7 17 5.6 0.2 9.2 7 3 5 12 12 12 0 C2H2-type zinc finger PHD_2 PF13831.6 OWF53142.1 - 0.076 12.6 6.6 1.6 8.4 0.1 3.2 2 1 2 4 4 4 0 PHD-finger Homeodomain PF00046.29 OWF53143.1 - 6.9e-22 77.0 6.3 6.9e-22 77.0 6.3 1.8 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 OWF53144.1 - 3.5e-22 78.0 6.9 5.3e-22 77.4 6.9 1.3 1 0 0 1 1 1 1 Homeodomain Ammonium_transp PF00909.21 OWF53145.1 - 6.3e-77 258.9 17.6 8.1e-77 258.6 17.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Sulfotransfer_1 PF00685.27 OWF53146.1 - 2.9e-16 59.8 0.0 5.6e-16 58.8 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF53146.1 - 8.6e-13 49.2 0.7 1.5e-11 45.2 0.7 2.6 1 1 0 1 1 1 1 Sulfotransferase family GCD14_N PF14801.6 OWF53148.1 - 2.4e-05 24.0 21.8 2.5 8.0 0.5 7.6 2 2 6 8 8 8 4 tRNA methyltransferase complex GCD14 subunit N-term Rieske_3 PF18465.1 OWF53148.1 - 0.0042 17.3 12.4 4.7 7.5 0.5 4.6 1 1 4 5 5 5 2 Rieske 3Fe-4S GPI-anchored PF10342.9 OWF53148.1 - 0.017 15.8 2.3 2.6 8.9 1.5 3.8 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FtsK_SpoIIIE_N PF12538.8 OWF53148.1 - 0.034 14.4 16.0 2.5 8.3 11.3 3.3 1 1 1 2 2 2 0 DNA transporter Minor_capsid_1 PF10665.9 OWF53148.1 - 0.039 14.1 7.7 8.9 6.6 0.1 5.2 1 1 4 5 5 5 0 Minor capsid protein Oxidored_q6 PF01058.22 OWF53148.1 - 0.088 12.6 7.4 3.6e+02 0.9 7.4 4.4 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit CHB_HEX PF03173.13 OWF53148.1 - 0.2 11.3 21.2 3 7.5 1.4 5.2 1 1 3 4 4 4 0 Putative carbohydrate binding domain DUF5544 PF17698.1 OWF53148.1 - 0.24 11.5 6.4 30 4.7 0.3 4.5 1 1 3 4 4 4 0 Family of unknown function (DUF5544) Foamy_virus_ENV PF03408.14 OWF53148.1 - 7.7 4.2 12.9 9.4 3.9 2.1 3.5 1 1 2 3 3 3 0 Foamy virus envelope protein PIN_5 PF08745.11 OWF53149.1 - 0.59 9.5 7.2 11 5.4 0.2 2.8 1 1 3 4 4 4 0 PINc domain ribonuclease RIF5_SNase_1 PF18187.1 OWF53149.1 - 0.89 9.3 12.2 0.13 12.0 1.7 3.9 1 1 3 4 4 4 0 TbRIF5 SNase domain 1 MreB_Mbl PF06723.13 OWF53149.1 - 1.4 7.7 5.1 23 3.7 0.1 2.9 1 1 2 3 3 3 0 MreB/Mbl protein CDI PF02234.19 OWF53150.1 - 1.1e-09 38.4 0.0 2.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 7tm_2 PF00002.24 OWF53151.1 - 3.8e-48 163.9 28.8 6.5e-48 163.2 28.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cadherin PF00028.17 OWF53151.1 - 4.8e-45 151.9 19.0 5.5e-11 42.8 0.2 10.9 9 2 1 10 10 10 7 Cadherin domain GPS PF01825.21 OWF53151.1 - 4.3e-15 55.9 6.5 1.7e-14 54.1 6.5 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 OWF53151.1 - 2.2e-11 43.6 0.2 4.1e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain I-set PF07679.16 OWF53151.1 - 5.8e-11 42.3 0.1 0.00042 20.3 0.1 4.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF53151.1 - 7.7e-11 42.2 1.2 0.00032 21.0 0.0 3.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 OWF53151.1 - 7.6e-10 39.3 4.9 5.3e-05 23.7 0.0 4.4 5 0 0 5 5 2 2 Immunoglobulin domain SEA PF01390.20 OWF53151.1 - 2.6e-08 33.9 0.3 5.5e-07 29.7 0.1 3.0 2 0 0 2 2 2 1 SEA domain HRM PF02793.22 OWF53151.1 - 7.4e-07 29.4 1.2 2e-06 28.0 1.2 1.8 1 0 0 1 1 1 1 Hormone receptor domain fn3 PF00041.21 OWF53151.1 - 0.00021 21.6 0.9 0.0013 19.0 0.9 2.5 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.17 OWF53151.1 - 0.0019 18.4 0.3 3.6 7.8 0.0 3.7 3 0 0 3 3 3 1 Immunoglobulin V-set domain EGF PF00008.27 OWF53151.1 - 0.002 18.4 4.7 0.002 18.4 4.7 3.8 3 0 0 3 3 3 1 EGF-like domain Cadherin_pro PF08758.11 OWF53151.1 - 0.029 14.5 0.2 11 6.3 0.0 4.0 5 0 0 5 5 4 0 Cadherin prodomain like DUF4492 PF14899.6 OWF53151.1 - 0.11 12.5 0.3 0.28 11.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Frizzled PF01534.17 OWF53151.1 - 0.3 10.1 23.3 71 2.3 23.1 2.3 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region UCH PF00443.29 OWF53152.1 - 1.4e-41 142.7 0.0 1.1e-37 129.9 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Nexin_C PF08628.12 OWF53152.1 - 0.19 12.3 1.4 1.2 9.8 1.4 2.4 1 0 0 1 1 1 0 Sorting nexin C terminal UCH PF00443.29 OWF53153.1 - 9.4e-42 143.3 0.0 6.9e-41 140.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF53153.1 - 5.7e-12 45.9 0.5 3.3e-10 40.1 0.5 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UME PF08064.13 OWF53153.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain EphA2_TM PF14575.6 OWF53153.1 - 0.065 14.1 0.0 0.17 12.8 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.15 OWF53153.1 - 0.12 12.3 0.5 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit DUF4500 PF14937.6 OWF53153.1 - 0.13 12.3 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Orthoreo_P10 PF07204.11 OWF53153.1 - 0.2 11.6 0.7 0.49 10.4 0.7 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF3644 PF12358.8 OWF53153.1 - 2.1 8.9 4.0 1.3 9.6 0.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3644) HEPN_DZIP3 PF18738.1 OWF53154.1 - 6e-28 97.4 0.0 4.9e-27 94.4 0.0 2.3 2 0 0 2 2 2 1 DZIP3/ hRUL138-like HEPN HEPN_MAE_28990 PF18737.1 OWF53154.1 - 0.021 14.8 0.4 0.25 11.2 0.0 2.5 3 0 0 3 3 3 0 MAE_28990/MAE_18760-like HEPN HEPN_Cthe2314 PF18730.1 OWF53154.1 - 0.23 11.5 0.0 0.23 11.5 0.0 3.0 3 1 1 4 4 4 0 Cthe_2314-like HEPN HEPN_DZIP3 PF18738.1 OWF53155.1 - 1.5e-18 66.9 1.4 2.7e-18 66.1 0.0 2.2 3 0 0 3 3 3 1 DZIP3/ hRUL138-like HEPN PyocinActivator PF11112.8 OWF53157.1 - 0.071 13.2 0.2 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Pyocin activator protein PrtN zf-C2H2_jaz PF12171.8 OWF53159.1 - 1.4e-09 38.0 4.7 1.4e-09 38.0 4.7 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF53159.1 - 0.0019 18.5 0.4 0.0031 17.8 0.2 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 OWF53159.1 - 0.02 14.7 1.9 0.038 13.7 1.9 1.5 1 0 0 1 1 1 0 U1 zinc finger zf-RRN7 PF11781.8 OWF53159.1 - 0.04 13.6 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DnaG_DnaB_bind PF08278.11 OWF53159.1 - 0.049 14.2 0.0 0.068 13.8 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding UPF0167 PF03691.14 OWF53159.1 - 0.083 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-met PF12874.7 OWF53159.1 - 0.12 12.8 1.4 0.2 12.1 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Herpes_teg_N PF04843.12 OWF53161.1 - 6.7e-09 35.6 0.0 4.4e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Herpesvirus tegument protein, N-terminal conserved region Gemini_AL1_M PF08283.11 OWF53162.1 - 0.019 15.1 0.9 0.045 13.8 0.4 2.0 2 0 0 2 2 2 0 Geminivirus rep protein central domain LprI PF07007.12 OWF53162.1 - 0.1 13.3 2.4 0.3 11.7 2.4 1.8 1 0 0 1 1 1 0 Lysozyme inhibitor LprI zf-C2H2 PF00096.26 OWF53163.1 - 1.1e-57 189.3 155.5 1.8e-06 28.0 0.2 18.5 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF53163.1 - 2.3e-56 183.5 139.9 9.8e-05 22.9 0.4 18.6 18 0 0 18 18 18 18 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF53163.1 - 2.4e-53 176.3 141.9 6.6e-08 32.6 1.3 19.8 19 1 0 19 19 19 12 Zinc-finger double domain zf-C2H2_6 PF13912.6 OWF53163.1 - 4.1e-23 80.9 129.6 0.038 14.0 0.1 18.1 18 0 0 18 18 18 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF53163.1 - 6.2e-18 64.6 100.0 0.0019 18.4 0.4 17.8 18 0 0 18 18 18 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF53163.1 - 2.4e-12 46.8 97.1 0.018 15.4 0.1 18.1 18 0 0 18 18 18 7 Zinc-finger of C2H2 type GAGA PF09237.11 OWF53163.1 - 5.2e-07 29.4 14.0 0.33 10.8 0.1 7.8 5 2 3 8 8 8 3 GAGA factor zinc_ribbon_15 PF17032.5 OWF53163.1 - 0.00023 21.9 69.6 0.39 11.5 1.0 9.6 5 2 4 9 9 9 5 zinc-ribbon family zf-C2H2_2 PF12756.7 OWF53163.1 - 0.0021 18.4 0.4 0.0021 18.4 0.4 13.6 4 3 8 13 13 13 2 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 OWF53163.1 - 0.0044 17.0 1.6 0.0044 17.0 1.6 10.1 8 3 3 11 11 11 2 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 OWF53163.1 - 0.031 14.0 0.1 0.031 14.0 0.1 14.4 17 0 0 17 17 16 0 zinc-finger C2H2-type BolA PF01722.18 OWF53163.1 - 0.05 13.9 18.8 0.55 10.6 0.1 6.4 5 3 0 5 5 5 0 BolA-like protein zf-C2H2_9 PF16293.5 OWF53163.1 - 0.14 12.0 0.1 0.14 12.0 0.1 9.9 8 3 4 12 12 12 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 OWF53163.1 - 0.36 10.8 0.1 0.36 10.8 0.1 14.6 17 0 0 17 17 16 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 OWF53163.1 - 1.2 9.3 81.9 0.046 13.8 2.5 11.9 6 4 9 15 15 15 0 Zinc ribbon domain Prokineticin PF06607.11 OWF53164.1 - 0.54 10.6 8.9 0.87 9.9 8.9 1.4 1 1 0 1 1 1 0 Prokineticin Bcl-2 PF00452.19 OWF53166.1 - 1.5e-05 25.6 0.0 5.4e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Ribosomal_L23 PF00276.20 OWF53167.1 - 1.6e-10 41.2 0.2 3.1e-10 40.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF5081 PF16887.5 OWF53167.1 - 0.0099 15.0 0.3 0.017 14.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5081) Peptidase_M48_N PF16491.5 OWF53168.1 - 1.7e-66 223.6 8.2 1.7e-66 223.6 8.2 2.2 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OWF53168.1 - 5.8e-58 195.9 0.0 8e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 CDC45 PF02724.14 OWF53168.1 - 0.033 12.5 1.0 0.047 12.0 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2798 PF11391.8 OWF53168.1 - 0.32 11.0 4.7 0.51 10.4 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) BIR PF00653.21 OWF53169.1 - 5.6e-11 42.9 0.3 1.1e-10 42.0 0.3 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain BIR PF00653.21 OWF53170.1 - 2.2e-06 28.2 0.4 4.8e-06 27.1 0.4 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain BIR PF00653.21 OWF53171.1 - 6.8e-19 68.3 0.2 6.8e-19 68.3 0.2 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF53171.1 - 5.2e-16 58.2 6.0 1.9e-14 53.3 6.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF53171.1 - 6.3e-07 29.1 8.1 2e-06 27.5 8.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF53171.1 - 0.00062 20.1 8.0 0.00062 20.1 8.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF53171.1 - 0.0077 16.2 7.5 0.0077 16.2 7.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF53171.1 - 0.0094 15.8 8.7 0.0094 15.8 8.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF53171.1 - 0.051 13.6 3.2 0.19 11.8 3.2 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DUF4139 PF13598.6 OWF53171.1 - 0.059 13.1 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) zf-C3HC4_4 PF15227.6 OWF53171.1 - 0.15 12.2 5.5 0.12 12.6 0.9 2.8 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DUF1421 PF07223.11 OWF53171.1 - 0.2 11.5 0.0 0.44 10.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) TMEM154 PF15102.6 OWF53172.1 - 0.016 15.1 1.8 0.029 14.3 1.8 1.4 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 OWF53172.1 - 0.7 10.0 3.4 1.3 9.1 3.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SAP PF02037.27 OWF53173.1 - 0.01 15.6 0.1 5 7.0 0.0 2.5 2 0 0 2 2 2 0 SAP domain GD_N PF16030.5 OWF53173.1 - 0.15 12.4 0.0 0.95 9.8 0.0 2.1 2 0 0 2 2 2 0 Serine protease gd N-terminus MGC-24 PF05283.11 OWF53174.1 - 1.6e-22 80.4 6.3 1.6e-22 80.4 6.3 3.1 1 1 2 3 3 3 2 Multi-glycosylated core protein 24 (MGC-24), sialomucin DEC-1_N PF04625.13 OWF53174.1 - 0.47 9.4 16.3 0.48 9.4 15.4 1.4 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region MGC-24 PF05283.11 OWF53175.1 - 6.9e-05 23.3 7.6 0.00084 19.8 7.6 2.0 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pro_isomerase PF00160.21 OWF53176.1 - 1.2e-42 145.9 0.0 1.6e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tctex-1 PF03645.13 OWF53177.1 - 1.7e-19 69.9 0.8 4.1e-19 68.7 0.1 1.8 2 0 0 2 2 2 1 Tctex-1 family zf-C4 PF00105.18 OWF53179.1 - 1.5e-21 76.6 13.4 1.5e-21 76.6 13.4 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF53179.1 - 1.4e-17 64.0 1.4 1.4e-17 64.0 1.4 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor PIN_6 PF17146.4 OWF53179.1 - 0.044 14.3 1.6 0.57 10.7 0.1 2.3 1 1 1 2 2 2 0 PIN domain of ribonuclease zf-RRPl_C4 PF17026.5 OWF53179.1 - 0.42 10.7 11.6 1.3 9.2 11.6 1.9 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Homeodomain PF00046.29 OWF53180.1 - 2.4e-19 68.9 5.2 4.7e-19 68.0 5.2 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF53180.1 - 0.00035 20.0 0.2 0.00086 18.7 0.2 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF53180.1 - 0.0076 16.1 0.2 0.029 14.2 0.2 2.0 1 0 0 1 1 1 1 Homeobox KN domain Phage_Mu_Gam PF07352.12 OWF53180.1 - 0.046 13.6 0.9 0.32 10.9 0.2 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein zf-RRN7 PF11781.8 OWF53181.1 - 0.00045 19.8 1.1 0.001 18.7 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 A2L_zn_ribbon PF08792.10 OWF53181.1 - 0.0013 18.4 2.9 0.0037 17.0 2.9 1.8 1 0 0 1 1 1 1 A2L zinc ribbon domain TFIIB PF00382.19 OWF53181.1 - 0.021 14.8 0.0 0.078 13.0 0.0 1.9 1 1 0 1 1 1 0 Transcription factor TFIIB repeat zf-RING_13 PF17977.1 OWF53181.1 - 0.033 14.3 0.7 0.17 12.1 0.5 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LAT PF15234.6 OWF53181.1 - 4 7.1 12.0 6.8 6.3 12.0 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells YHYH PF14240.6 OWF53182.1 - 5.2e-23 82.0 0.1 6e-15 55.7 0.0 2.6 1 1 1 2 2 2 2 YHYH protein MAGI_u5 PF16666.5 OWF53182.1 - 4.8 7.3 12.2 5.7 7.1 0.7 3.8 3 0 0 3 3 3 0 Unstructured region on MAGI SRCR PF00530.18 OWF53183.1 - 1.3e-13 51.3 21.8 9.8e-10 38.8 8.4 5.4 5 0 0 5 5 5 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF53183.1 - 0.0028 18.1 23.5 0.016 15.8 6.1 3.7 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain RCR PF12273.8 OWF53183.1 - 0.041 14.5 0.4 15 6.3 0.0 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 OWF53183.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family DBP PF12361.8 OWF53183.1 - 0.25 11.2 16.4 2.5 7.9 4.0 2.5 1 1 1 2 2 2 0 Duffy-antigen binding protein MLANA PF14991.6 OWF53183.1 - 0.34 11.2 1.3 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein melan-A PKI PF02827.16 OWF53184.1 - 0.039 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Endonuc-MspI PF09208.10 OWF53184.1 - 0.06 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease MspI RGS12_us1 PF16613.5 OWF53184.1 - 0.56 10.5 11.6 70 3.8 0.0 3.3 2 1 0 2 2 2 0 Unstructured region of RGS12 Kelch_1 PF01344.25 OWF53185.1 - 2.3e-62 206.3 20.9 2.6e-12 46.1 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 OWF53185.1 - 1.5e-31 107.2 8.6 9.1e-07 28.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OWF53185.1 - 2.2e-25 88.4 5.7 0.0001 22.2 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF53185.1 - 2.7e-25 87.8 12.3 5.4e-06 26.5 0.1 6.5 2 1 4 6 6 6 5 Kelch motif BACK PF07707.15 OWF53185.1 - 9.3e-25 86.7 0.2 1.8e-24 85.8 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 OWF53185.1 - 6.2e-22 77.9 0.0 3.1e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 OWF53185.1 - 1e-18 67.1 7.3 0.012 15.9 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF53185.1 - 2.8e-11 43.1 18.8 0.0014 18.5 0.2 6.2 5 1 1 6 6 6 3 Kelch motif PQQ_3 PF13570.6 OWF53185.1 - 0.059 13.9 0.1 0.059 13.9 0.1 4.5 5 0 0 5 5 5 0 PQQ-like domain Pkinase PF00069.25 OWF53186.1 - 9.3e-64 215.3 0.0 9.3e-64 215.3 0.0 2.9 3 1 0 3 3 3 1 Protein kinase domain PKK PF12474.8 OWF53186.1 - 6e-58 194.9 95.3 2e-33 115.4 40.3 6.2 5 1 1 6 6 6 2 Polo kinase kinase Pkinase_Tyr PF07714.17 OWF53186.1 - 1.3e-48 165.5 0.0 1.3e-48 165.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase DUF883 PF05957.13 OWF53186.1 - 0.21 12.2 0.0 0.21 12.2 0.0 6.3 4 2 3 8 8 8 0 Bacterial protein of unknown function (DUF883) CENP-S PF15630.6 OWF53187.1 - 2.1e-25 88.9 0.7 2.1e-25 88.9 0.7 1.5 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 OWF53187.1 - 4.5e-13 49.3 0.6 6.4e-13 48.8 0.5 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OWF53187.1 - 7.1e-06 26.4 0.3 7.1e-06 26.4 0.3 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OWF53187.1 - 3.6e-05 23.8 0.2 5.7e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DegS PF05384.11 OWF53187.1 - 0.00032 20.2 0.6 0.00047 19.7 0.6 1.3 1 0 0 1 1 1 1 Sensor protein DegS Bromo_TP PF07524.13 OWF53187.1 - 0.00065 19.7 0.0 0.00097 19.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 OWF53187.1 - 0.00084 19.8 0.2 0.0016 18.9 0.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAF PF02969.17 OWF53187.1 - 0.0021 18.2 0.1 0.0049 17.0 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OWF53187.1 - 0.0024 18.1 0.2 0.0024 18.1 0.2 1.7 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 OWF53187.1 - 0.0027 17.7 0.4 0.0043 17.1 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit COMMD1_N PF17221.3 OWF53187.1 - 0.028 14.7 0.3 0.028 14.7 0.3 1.6 2 0 0 2 2 2 0 COMMD1 N-terminal domain ERAP1_C PF11838.8 OWF53188.1 - 4.7e-85 285.9 0.1 6e-85 285.5 0.1 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF1138 PF06592.13 OWF53188.1 - 0.17 11.9 0.8 0.68 10.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1138) Collagen PF01391.18 OWF53189.1 - 4.1e-22 77.7 76.3 3.5e-09 36.3 30.5 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) CCSMST1 PF15013.6 OWF53189.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 CCSMST1 family MAM PF00629.23 OWF53190.1 - 1.8e-110 366.0 0.1 4.3e-39 134.0 0.0 3.7 4 0 0 4 4 4 3 MAM domain, meprin/A5/mu Ig_3 PF13927.6 OWF53190.1 - 1.7e-23 83.0 21.3 1.1e-12 48.3 0.4 4.5 5 0 0 5 5 5 2 Immunoglobulin domain I-set PF07679.16 OWF53190.1 - 3.3e-21 75.2 0.0 1.9e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain Collagen PF01391.18 OWF53190.1 - 7.4e-20 70.5 60.7 2.7e-08 33.5 17.5 3.7 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Ig_2 PF13895.6 OWF53190.1 - 1.5e-19 70.1 14.5 7.1e-10 39.1 0.3 3.7 3 1 1 4 4 4 2 Immunoglobulin domain ig PF00047.25 OWF53190.1 - 5.8e-16 58.4 7.4 1.6e-07 31.4 0.1 4.0 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 OWF53190.1 - 4.1e-06 26.9 3.0 0.11 12.6 0.0 5.2 3 2 2 5 5 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF53190.1 - 0.00029 20.8 1.5 0.26 11.4 0.2 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF53190.1 - 0.0016 18.8 0.0 1 9.8 0.0 3.1 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF53190.1 - 0.11 12.1 0.0 5.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain CBM_6 PF03422.15 OWF53190.1 - 0.8 10.0 7.4 2.1 8.7 0.2 3.9 4 1 0 4 4 4 0 Carbohydrate binding module (family 6) Ykof PF07615.11 OWF53191.1 - 0.00048 20.5 1.7 4.8 7.7 0.0 4.2 1 1 4 5 5 5 2 YKOF-related Family DUF4219 PF13961.6 OWF53191.1 - 0.0037 16.9 8.5 68 3.3 0.0 6.6 7 0 0 7 7 7 0 Domain of unknown function (DUF4219) Binary_toxB_2 PF17475.2 OWF53191.1 - 0.011 15.5 1.6 1.1 9.0 0.1 3.2 1 1 3 4 4 4 0 Clostridial binary toxin B/anthrax toxin PA domain 2 Mo-co_dimer PF03404.16 OWF53191.1 - 0.025 14.6 0.7 5.7 7.0 0.1 2.7 1 1 3 4 4 4 0 Mo-co oxidoreductase dimerisation domain ABC_trans_aux PF03886.13 OWF53191.1 - 0.096 12.3 5.6 4.2 6.9 0.2 2.9 1 1 2 3 3 3 0 ABC-type transport auxiliary lipoprotein component Thymopoietin PF08198.11 OWF53191.1 - 0.13 11.8 3.1 6.8 6.4 0.1 3.1 2 1 2 4 4 4 0 Thymopoietin protein DUF2559 PF10832.8 OWF53191.1 - 0.44 10.7 18.5 17 5.6 0.5 5.8 1 1 3 5 5 5 0 Protein of unknown function (DUF2559) Paz_1 PF18349.1 OWF53191.1 - 0.49 10.4 2.0 2.8 7.9 0.2 2.4 1 1 1 2 2 2 0 PAZ domain MFS_1 PF07690.16 OWF53192.1 - 2.6e-17 62.8 29.4 2.6e-17 62.8 29.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF53192.1 - 0.62 8.8 39.3 0.13 11.1 8.4 3.2 3 1 0 3 3 3 0 Sugar (and other) transporter Pentapeptide PF00805.22 OWF53193.1 - 0.0041 16.7 6.9 6.7 6.5 0.1 4.4 4 0 0 4 4 4 2 Pentapeptide repeats (8 copies) LPP20 PF02169.16 OWF53193.1 - 0.95 9.9 26.7 6.1 7.3 1.4 4.9 4 0 0 4 4 4 0 LPP20 lipoprotein TOC159_MAD PF11886.8 OWF53193.1 - 5.6 5.8 6.3 2.1 7.2 0.2 3.2 2 2 2 5 5 5 0 Translocase of chloroplast 159/132, membrane anchor domain AT_hook PF02178.19 OWF53194.1 - 0.0021 17.7 44.3 0.07 13.0 2.0 5.9 5 0 0 5 5 5 5 AT hook motif CUB PF00431.20 OWF53195.1 - 5.3e-67 223.1 0.0 3.6e-23 82.0 0.0 3.5 3 0 0 3 3 3 3 CUB domain Trypsin PF00089.26 OWF53195.1 - 8.4e-51 172.9 0.0 1.3e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin Ig_3 PF13927.6 OWF53195.1 - 4.1e-15 56.2 0.0 1.4e-10 41.6 0.2 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 OWF53195.1 - 1e-12 47.9 0.0 5.5e-10 39.2 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.25 OWF53195.1 - 1.4e-12 47.6 0.7 7.1e-10 38.9 0.5 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 OWF53195.1 - 5.2e-07 29.9 0.2 7.5e-06 26.2 0.1 2.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 OWF53195.1 - 2.7e-06 27.5 3.5 0.14 12.3 0.4 5.3 4 1 0 4 4 4 1 Immunoglobulin V-set domain DUF1986 PF09342.11 OWF53195.1 - 0.023 15.1 0.0 0.12 12.8 0.0 2.2 2 1 0 2 2 1 0 Domain of unknown function (DUF1986) Adeno_E3_CR1 PF02440.15 OWF53195.1 - 0.27 11.1 2.6 0.53 10.1 0.1 2.7 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 Antimicrobial25 PF16839.5 OWF53195.1 - 1.6 8.8 7.7 5.1 7.3 7.7 1.9 1 0 0 1 1 1 0 Nematode antimicrobial peptide EGF_2 PF07974.13 OWF53195.1 - 3.8 8.0 14.3 0.54 10.7 8.2 2.9 2 0 0 2 2 2 0 EGF-like domain AAA_12 PF13087.6 OWF53196.1 - 5.2e-47 160.1 0.0 9.6e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OWF53196.1 - 5.8e-29 101.7 0.0 3.2e-14 53.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 OWF53196.1 - 1.6e-08 34.5 0.0 7.3e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF53196.1 - 3.3e-06 27.5 0.0 1.4e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OWF53196.1 - 1.6e-05 25.0 0.0 3.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-met PF12874.7 OWF53196.1 - 0.00038 20.7 0.1 0.0015 18.8 0.1 2.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type UvrD-helicase PF00580.21 OWF53196.1 - 0.004 16.7 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 OWF53196.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OWF53196.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 OWF53196.1 - 0.031 13.5 0.0 0.45 9.6 0.0 2.5 3 0 0 3 3 3 0 PIF1-like helicase AAA PF00004.29 OWF53196.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OWF53196.1 - 0.056 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OWF53196.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OWF53196.1 - 0.088 11.9 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein LIM PF00412.22 OWF53197.1 - 1.1e-08 35.1 8.6 2.4e-08 34.1 8.6 1.5 1 0 0 1 1 1 1 LIM domain C1q PF00386.21 OWF53198.1 - 9.6e-21 74.3 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF53198.1 - 0.011 15.6 0.2 0.022 14.7 0.2 1.5 1 0 0 1 1 1 0 BclA C-terminal domain Sugarporin_N PF11471.8 OWF53198.1 - 0.037 14.0 2.1 0.079 12.9 2.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension C1q PF00386.21 OWF53199.1 - 2.7e-26 92.3 0.2 5.8e-26 91.2 0.0 1.6 2 0 0 2 2 2 1 C1q domain PDGLE PF13190.6 OWF53199.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 PDGLE domain Sugarporin_N PF11471.8 OWF53199.1 - 0.0018 18.2 1.0 0.0028 17.6 0.4 1.6 1 1 1 2 2 2 1 Maltoporin periplasmic N-terminal extension HrpB7 PF09486.10 OWF53199.1 - 0.0025 18.2 1.5 0.0037 17.7 1.5 1.2 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) KxDL PF10241.9 OWF53199.1 - 0.0036 17.5 1.2 0.0059 16.9 1.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein Cep57_MT_bd PF06657.13 OWF53199.1 - 0.0039 17.6 1.5 0.0068 16.8 1.5 1.4 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 MscS_porin PF12795.7 OWF53199.1 - 0.0074 15.9 4.3 0.0096 15.5 4.3 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain FPP PF05911.11 OWF53199.1 - 0.0099 14.1 0.9 0.012 13.8 0.9 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil COG2 PF06148.11 OWF53199.1 - 0.013 15.6 1.0 0.02 15.0 1.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.7 OWF53199.1 - 0.015 15.5 1.1 0.02 15.0 1.1 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF4349 PF14257.6 OWF53199.1 - 0.018 14.5 0.7 0.03 13.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) BclA_C PF18573.1 OWF53199.1 - 0.022 14.7 0.2 0.033 14.1 0.2 1.2 1 0 0 1 1 1 0 BclA C-terminal domain DUF2353 PF09789.9 OWF53199.1 - 0.024 14.0 1.0 0.032 13.6 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) OmpH PF03938.14 OWF53199.1 - 0.024 14.9 2.5 0.042 14.2 1.5 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 OWF53199.1 - 0.029 13.3 1.2 0.036 13.0 1.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 OWF53199.1 - 0.055 13.6 0.7 0.084 13.0 0.7 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 EzrA PF06160.12 OWF53199.1 - 0.07 11.3 2.6 0.091 10.9 2.6 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GrpE PF01025.19 OWF53199.1 - 0.073 12.7 1.6 0.11 12.2 1.6 1.1 1 0 0 1 1 1 0 GrpE BRCT PF00533.26 OWF53199.1 - 0.081 13.3 0.0 2.7 8.4 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain TolA_bind_tri PF16331.5 OWF53199.1 - 0.091 12.8 4.5 0.13 12.3 4.5 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation DLP_helical PF18709.1 OWF53199.1 - 0.14 11.3 1.5 0.21 10.8 1.5 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain GyrI-like PF06445.15 OWF53200.1 - 0.00058 20.2 0.2 0.0025 18.1 0.1 2.0 1 1 1 2 2 2 1 GyrI-like small molecule binding domain BLOC1S3 PF15753.5 OWF53200.1 - 2.5 8.2 7.4 4 7.5 7.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Pkinase_Tyr PF07714.17 OWF53201.1 - 1.4e-76 257.3 0.0 2.8e-76 256.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Sema PF01403.19 OWF53201.1 - 1.7e-36 126.0 0.0 2.7e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.25 OWF53201.1 - 3.2e-33 115.2 0.0 1.1e-32 113.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain TIG PF01833.24 OWF53201.1 - 2.2e-27 94.9 14.9 3.5e-12 46.2 0.0 6.3 6 0 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 OWF53201.1 - 6.9e-19 68.3 0.2 8.1e-17 61.6 0.1 3.3 3 0 0 3 3 3 1 TIG domain found in plexin PSI PF01437.25 OWF53201.1 - 1.3e-12 48.0 48.8 7.6e-06 26.4 12.3 3.7 3 0 0 3 3 3 3 Plexin repeat TIG_plexin PF17960.1 OWF53201.1 - 2.2e-07 30.8 1.8 0.0023 17.9 0.0 4.5 4 0 0 4 4 4 2 TIG domain Mid2 PF04478.12 OWF53201.1 - 0.1 12.4 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Glycophorin_A PF01102.18 OWF53201.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A RIO1 PF01163.22 OWF53201.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Apolipoprotein PF01442.18 OWF53202.1 - 2.5e-06 27.5 0.0 1.4e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4417 PF14386.6 OWF53202.1 - 3e-05 23.7 12.7 3.1 7.3 0.0 6.4 1 1 5 6 6 6 1 Domain of unknown function (DUF4417) Baculo_PEP_C PF04513.12 OWF53202.1 - 0.00019 21.5 0.5 0.16 12.0 0.5 3.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_42M PF08532.10 OWF53202.1 - 0.00027 20.5 0.2 11 5.4 0.0 4.0 1 1 4 6 6 6 2 Beta-galactosidase trimerisation domain YqcI_YcgG PF08892.11 OWF53202.1 - 0.0011 18.9 0.1 6.6 6.5 0.0 3.6 1 1 5 6 6 6 1 YqcI/YcgG family Phage_portal PF04860.12 OWF53202.1 - 0.0011 18.3 0.2 2.7 7.1 0.0 3.0 1 1 2 3 3 3 1 Phage portal protein Prominin PF05478.11 OWF53202.1 - 0.0011 17.0 1.3 0.0016 16.5 1.3 1.2 1 0 0 1 1 1 1 Prominin Amdo_NSP PF12475.8 OWF53202.1 - 0.012 15.7 15.1 12 6.1 0.1 6.7 1 1 6 7 7 7 0 Amdovirus non-structural protein Vel1p PF10339.9 OWF53202.1 - 0.1 12.0 5.5 2.1 7.7 0.3 3.4 1 1 3 4 4 4 0 Yeast-specific zinc responsive Fib_alpha PF08702.10 OWF53202.1 - 0.1 12.8 2.4 2.9 8.1 2.4 2.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SPICE PF15678.5 OWF53202.1 - 0.2 11.0 3.4 0.35 10.1 1.2 2.0 1 1 1 2 2 2 0 Centriole duplication and mitotic chromosome congression BORCS6 PF10157.9 OWF53202.1 - 1.1 9.5 5.2 8.9 6.5 0.9 2.2 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 DUF2990 PF11693.8 OWF53202.1 - 4.4 7.5 10.4 17 5.6 0.3 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2990) DUF1057 PF06342.12 OWF53204.1 - 0.027 13.5 0.0 1.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Ferric_reduct PF01794.19 OWF53204.1 - 0.89 9.7 13.8 2.5 8.2 2.2 3.0 1 1 2 3 3 3 0 Ferric reductase like transmembrane component Sema PF01403.19 OWF53205.1 - 2.7e-45 155.0 0.1 3.4e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 OWF53205.1 - 2e-07 31.4 7.4 4.6e-07 30.3 7.4 1.7 1 0 0 1 1 1 1 Plexin repeat Pep3_Vps18 PF05131.14 OWF53205.1 - 0.0042 16.9 1.9 0.027 14.3 0.2 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family PSI_integrin PF17205.3 OWF53205.1 - 0.0056 16.4 6.3 0.018 14.8 6.3 2.0 1 0 0 1 1 1 1 Integrin plexin domain DUF765 PF05570.11 OWF53206.1 - 1.1e-06 28.7 15.9 1.6e+02 2.6 0.0 12.4 14 0 0 14 14 14 0 Circovirus protein of unknown function (DUF765) HIM1 PF08732.10 OWF53206.1 - 0.0011 18.5 6.4 17 4.9 0.1 5.6 1 1 5 6 6 6 1 HIM1 TORC_C PF12886.7 OWF53206.1 - 0.002 18.6 6.9 35 5.1 0.1 5.2 1 1 7 8 8 8 0 Transducer of regulated CREB activity, C terminus AdoMet_dc PF02675.15 OWF53206.1 - 0.012 15.9 0.1 99 3.3 0.0 5.0 1 1 4 5 5 5 0 S-adenosylmethionine decarboxylase NPL4 PF05021.15 OWF53206.1 - 0.019 14.3 8.2 2.1 7.6 0.7 4.6 1 1 4 5 5 5 0 NPL4 family Pneumo_M2 PF07380.11 OWF53206.1 - 0.056 13.7 1.9 37 4.7 0.1 4.2 1 1 3 5 5 5 0 Pneumovirus M2 protein P3A PF08727.11 OWF53206.1 - 0.17 11.3 7.3 2.8e+02 1.0 0.0 7.5 6 3 5 11 11 11 0 Poliovirus 3A protein like Planc_extracel PF07595.12 OWF53206.1 - 0.45 10.4 10.4 41 4.2 0.0 7.1 10 0 0 10 10 10 0 Planctomycete extracellular CYYR1 PF10873.8 OWF53207.1 - 4.7e-06 27.1 8.0 6.9e-06 26.6 8.0 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Shisa PF13908.6 OWF53207.1 - 0.00014 22.2 0.3 0.00022 21.5 0.3 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.8 OWF53207.1 - 0.00087 19.9 0.5 0.013 16.1 0.0 2.1 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 OWF53207.1 - 0.021 15.7 0.1 0.13 13.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Prominin PF05478.11 OWF53207.1 - 3.4 5.5 8.5 4.7 5.0 8.5 1.1 1 0 0 1 1 1 0 Prominin DUF4550 PF15084.6 OWF53208.1 - 3.4e-27 94.7 0.8 9.5e-27 93.3 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4550) DrrA_P4M PF14860.6 OWF53208.1 - 0.016 15.0 0.4 0.1 12.5 0.4 2.4 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Chitin_synth_1 PF01644.17 OWF53208.1 - 0.2 11.7 10.9 1 9.4 0.4 3.7 4 0 0 4 4 4 0 Chitin synthase Caveolin PF01146.17 OWF53209.1 - 1.9e-43 147.6 0.6 2.1e-43 147.5 0.6 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53210.1 - 2.5e-37 127.8 0.9 2.7e-37 127.7 0.9 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53211.1 - 2.1e-36 124.8 0.3 2.3e-36 124.7 0.3 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53212.1 - 2.4e-37 127.9 0.6 2.8e-37 127.7 0.6 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53213.1 - 8.1e-47 158.5 1.4 1e-46 158.2 1.4 1.1 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53214.1 - 2.1e-39 134.6 0.1 2.2e-39 134.5 0.1 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53215.1 - 3.6e-39 133.8 0.1 3.8e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53216.1 - 2.4e-24 85.8 0.0 3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 OWF53217.1 - 1.3e-39 135.2 0.0 1.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Caveolin VGCC_alpha2 PF08473.11 OWF53218.1 - 6.4e-76 255.9 3.3 1.2e-75 254.9 3.3 1.4 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 OWF53218.1 - 6.9e-29 100.8 0.1 4.1e-28 98.3 0.0 2.5 2 0 0 2 2 2 1 VWA N-terminal VWA PF00092.28 OWF53218.1 - 1.2e-14 54.9 0.2 2.7e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF53218.1 - 1.6e-13 50.9 0.0 2.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 OWF53218.1 - 1.6e-08 34.6 2.2 1.1e-07 31.9 0.1 2.8 3 0 0 3 3 3 1 Cache domain VWA_2 PF13519.6 OWF53218.1 - 4.7e-08 33.6 0.1 1.2e-07 32.3 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ank_4 PF13637.6 OWF53219.1 - 2e-32 111.2 4.7 1.4e-08 35.1 0.1 7.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF53219.1 - 4.8e-29 100.8 9.9 2.6e-13 50.3 0.5 5.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF53219.1 - 3.6e-25 85.3 7.4 8.8e-05 22.6 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 OWF53219.1 - 3e-22 78.0 13.3 4.9e-06 26.7 0.2 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OWF53219.1 - 3.9e-19 68.5 5.8 4.9e-07 29.9 0.0 7.4 5 1 3 8 8 8 4 Ankyrin repeats (many copies) 7tm_1 PF00001.21 OWF53220.1 - 2.9e-60 203.8 9.4 3.9e-60 203.4 9.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF53220.1 - 3.6e-12 46.2 15.7 3.9e-06 26.4 8.5 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF53220.1 - 3.4e-09 36.7 18.7 3.4e-09 36.7 18.7 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF53220.1 - 0.0087 15.8 5.1 0.0087 15.8 5.1 1.8 2 0 0 2 2 2 1 Olfactory receptor Ank_2 PF12796.7 OWF53221.1 - 2.8e-35 120.8 3.3 1.3e-10 41.7 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53221.1 - 3.7e-23 81.6 0.1 1e-06 29.1 0.1 5.1 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF53221.1 - 1e-20 73.2 0.7 9.1e-05 22.7 0.0 6.9 5 1 1 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 OWF53221.1 - 1.5e-20 71.0 0.3 0.0021 18.4 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OWF53221.1 - 1.1e-18 67.1 1.3 1.6e-07 31.4 0.0 6.1 3 2 4 7 7 7 4 Ankyrin repeats (many copies) F5_F8_type_C PF00754.25 OWF53221.1 - 2.7e-09 37.2 0.0 5.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain SAM_1 PF00536.30 OWF53221.1 - 0.0074 16.7 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FdhE PF04216.12 OWF53221.1 - 0.063 13.2 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF4905 PF16248.5 OWF53222.1 - 8.9e-09 35.1 0.1 19 5.2 0.0 6.8 1 1 6 8 8 8 3 Domain of unknown function (DUF4905) SRR PF07709.11 OWF53222.1 - 2.5e-07 29.9 2.5 2.1e+02 3.0 0.0 9.6 11 0 0 11 11 11 0 Seven Residue Repeat TcfC PF16967.5 OWF53222.1 - 3.9e-07 29.4 2.8 1.9 8.0 0.1 4.6 1 1 7 8 8 8 7 E-set like domain DUF2555 PF10742.9 OWF53222.1 - 0.00012 21.8 0.0 7.5 6.5 0.0 6.0 4 3 5 9 9 9 1 Protein of unknown function (DUF2555) DUF3562 PF12085.8 OWF53222.1 - 0.00033 20.2 0.0 1.2e+02 2.4 0.0 5.6 5 1 0 6 6 6 0 Protein of unknown function (DUF3562) AvrPto PF11592.8 OWF53222.1 - 0.0024 17.9 0.0 12 6.0 0.0 4.0 1 1 2 4 4 4 1 Central core of the bacterial effector protein AvrPto Phosducin PF02114.16 OWF53223.1 - 9.3e-72 241.1 6.6 7.1e-71 238.2 6.6 2.0 1 1 0 1 1 1 1 Phosducin SseB_C PF14581.6 OWF53223.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 SseB protein C-terminal domain DUF3445 PF11927.8 OWF53223.1 - 0.04 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) PAP_central PF04928.17 OWF53223.1 - 0.12 11.3 0.3 0.14 11.1 0.3 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain CDH1_2_SANT_HL1 PF18375.1 OWF53223.1 - 0.27 12.0 8.8 0.63 10.7 0.0 3.4 3 1 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Pro_isomerase PF00160.21 OWF53224.1 - 4.3e-55 186.3 0.0 4.8e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MtrF PF09472.10 OWF53225.1 - 0.097 12.1 1.0 0.4 10.1 0.3 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syndecan PF01034.20 OWF53225.1 - 0.1 12.6 0.7 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 Syndecan domain DUF4260 PF14079.6 OWF53226.1 - 0.0071 16.3 2.0 0.023 14.6 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Syndecan PF01034.20 OWF53226.1 - 0.078 12.9 0.3 0.078 12.9 0.3 2.8 4 0 0 4 4 4 0 Syndecan domain zf-RING_UBOX PF13445.6 OWF53227.1 - 3.9e-10 39.6 6.2 3.9e-10 39.6 6.2 2.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF53227.1 - 9.5e-10 38.2 8.7 3.4e-09 36.4 8.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF53227.1 - 9.5e-08 32.3 9.7 2.3e-07 31.0 9.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF53227.1 - 1.9e-07 31.1 9.2 7.5e-07 29.2 9.2 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF53227.1 - 2.1e-07 30.7 7.3 2.1e-07 30.7 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF53227.1 - 9.6e-06 25.4 14.6 5.8e-05 22.9 14.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF53227.1 - 0.0012 18.8 13.1 0.0029 17.5 13.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 OWF53227.1 - 0.0031 17.4 2.1 0.0078 16.1 2.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OWF53227.1 - 0.04 13.7 7.6 0.11 12.2 7.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 OWF53227.1 - 0.35 10.8 11.9 0.69 9.8 10.3 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Pox_F11 PF04943.12 OWF53228.1 - 0.0053 15.9 0.0 0.0068 15.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus F11 protein APG6_N PF17675.1 OWF53228.1 - 0.024 15.2 7.6 0.032 14.8 7.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 OWF53228.1 - 0.039 14.0 0.6 0.039 14.0 0.6 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.21 OWF53228.1 - 0.11 12.6 2.9 5.3 7.2 0.1 2.5 1 1 1 2 2 2 0 bZIP transcription factor zf-C3HC4_4 PF15227.6 OWF53229.1 - 1.6e-10 40.9 5.4 7.4e-10 38.8 5.4 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF53229.1 - 8.9e-09 35.2 5.3 1.1e-08 35.0 3.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF53229.1 - 1.2e-07 31.5 8.8 1.2e-07 31.5 8.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF53229.1 - 5.4e-07 29.4 3.3 5.4e-07 29.4 3.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF53229.1 - 9.3e-07 28.6 7.6 2.7e-06 27.1 7.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF53229.1 - 1.2e-06 28.3 7.0 3.4e-06 26.9 7.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF53229.1 - 2.7e-06 27.6 7.8 2.7e-06 27.6 7.8 1.9 2 0 0 2 2 1 1 Ring finger domain Claudin_2 PF13903.6 OWF53229.1 - 0.011 15.5 0.2 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-RING_4 PF14570.6 OWF53229.1 - 0.047 13.5 6.4 0.66 9.8 6.4 2.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 OWF53229.1 - 0.11 12.4 2.8 0.16 11.9 1.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OWF53229.1 - 0.54 10.2 11.2 0.39 10.6 7.6 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OWF53229.1 - 7.3 6.4 9.7 2.4 8.0 5.8 2.3 2 0 0 2 2 2 0 RING-like zinc finger Lectin_C PF00059.21 OWF53230.1 - 1.8e-15 57.6 0.0 2.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF53230.1 - 0.029 14.0 0.2 0.064 12.9 0.0 1.5 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 OWF53231.1 - 2.4e-16 60.4 0.0 3.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF53231.1 - 0.00011 21.9 0.1 0.0029 17.3 0.0 2.0 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like GAS PF13851.6 OWF53232.1 - 0.0012 18.3 17.2 0.0012 18.3 17.2 7.1 2 1 5 7 7 7 2 Growth-arrest specific micro-tubule binding Bap31_Bap29_C PF18035.1 OWF53232.1 - 0.0067 16.4 0.6 0.0067 16.4 0.6 6.8 7 1 1 8 8 8 2 Bap31/Bap29 cytoplasmic coiled-coil domain Vezatin PF12632.7 OWF53233.1 - 1.6e-14 54.0 0.0 2.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes YbhQ PF11076.8 OWF53233.1 - 0.16 11.9 0.3 0.39 10.7 0.3 1.5 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF2040 PF09745.9 OWF53233.1 - 0.9 9.6 7.7 0.045 13.8 1.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Lipase_GDSL_2 PF13472.6 OWF53234.1 - 7.3e-22 78.6 0.0 9.2e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF53234.1 - 9.9e-22 77.9 0.0 6.3e-21 75.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhnJ PF06007.11 OWF53234.1 - 0.097 11.7 0.1 0.25 10.3 0.0 1.5 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnJ AAA_12 PF13087.6 OWF53235.1 - 1.9e-73 246.4 0.0 1.3e-39 135.9 0.0 4.0 3 0 0 3 3 3 2 AAA domain RNB PF00773.19 OWF53235.1 - 1.3e-53 182.5 0.0 4e-53 180.8 0.0 2.0 1 0 0 1 1 1 1 RNB domain AAA_11 PF13086.6 OWF53235.1 - 7.9e-49 166.8 23.0 4.1e-25 89.1 1.0 5.2 5 1 0 5 5 3 3 AAA domain AAA_30 PF13604.6 OWF53235.1 - 2.4e-10 40.4 0.0 1.2e-05 25.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OWF53235.1 - 7.5e-08 32.4 2.1 0.00073 19.3 0.0 4.1 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 OWF53235.1 - 2e-07 31.5 0.0 0.0036 17.6 0.0 3.6 2 1 0 2 2 2 2 AAA domain zf-C2H2_jaz PF12171.8 OWF53235.1 - 2.9e-05 24.2 4.1 9.6e-05 22.6 4.1 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding TPR_1 PF00515.28 OWF53235.1 - 6.2e-05 22.6 0.0 6.2e-05 22.6 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat UvrD_C PF13361.6 OWF53235.1 - 0.00097 18.6 2.4 0.17 11.2 0.0 3.5 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 OWF53235.1 - 0.0013 18.2 0.0 3 7.3 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein Helicase_RecD PF05127.14 OWF53235.1 - 0.0035 17.2 0.2 0.73 9.7 0.0 3.5 3 0 0 3 3 3 1 Helicase TPR_2 PF07719.17 OWF53235.1 - 0.0047 16.9 0.3 0.053 13.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.6 OWF53235.1 - 0.009 16.3 0.0 5.3 7.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OWF53235.1 - 0.013 15.5 0.0 0.072 13.1 0.0 2.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit p450 PF00067.22 OWF53235.1 - 0.02 13.7 0.0 0.044 12.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome P450 zf-C2H2_2 PF12756.7 OWF53235.1 - 0.041 14.2 2.9 0.37 11.2 2.9 2.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TPR_19 PF14559.6 OWF53235.1 - 0.049 14.1 0.7 0.16 12.5 0.5 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF53235.1 - 0.05 13.9 0.2 0.14 12.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-met PF12874.7 OWF53235.1 - 0.051 14.0 5.6 0.2 12.1 5.6 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SRP68 PF16969.5 OWF53236.1 - 8.3e-151 503.8 1.0 9.4e-151 503.6 1.0 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 OWF53236.1 - 0.0046 17.0 4.5 0.7 10.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF53236.1 - 0.0085 16.7 2.2 0.57 10.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF53236.1 - 0.07 13.4 2.8 8.2 6.8 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF53236.1 - 0.11 12.5 1.0 33 4.8 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF53236.1 - 0.83 9.9 3.9 4 7.7 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1374 PF07118.11 OWF53237.1 - 0.011 16.3 1.4 33 5.1 0.0 4.6 1 1 2 5 5 5 0 Protein of unknown function (DUF1374) CPW_WPC PF09717.10 OWF53237.1 - 0.43 11.6 11.4 75 4.4 0.0 5.4 3 1 2 5 5 5 0 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF5516 PF17637.2 OWF53237.1 - 0.56 10.0 10.7 28 4.6 0.1 7.2 4 3 2 6 6 6 0 Family of unknown function (DUF5516) Mu-transpos_C PF09299.11 OWF53237.1 - 3.6 7.6 8.5 1.3e+02 2.7 0.0 5.7 3 2 4 7 7 7 0 Mu transposase, C-terminal Tricorn_C1 PF14684.6 OWF53238.1 - 0.00038 20.5 0.6 12 6.0 0.0 4.0 1 1 3 4 4 4 3 Tricorn protease C1 domain PHB_acc PF05233.13 OWF53238.1 - 0.048 13.7 6.1 12 6.0 0.2 4.2 3 2 1 4 4 4 0 PHB accumulation regulatory domain DUF5645 PF18713.1 OWF53238.1 - 0.077 13.3 5.6 39 4.6 0.1 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF5645) Lipl32 PF12103.8 OWF53238.1 - 0.57 9.8 7.0 9.9 5.8 0.3 3.3 1 1 2 3 3 3 0 Surface lipoprotein of Spirochaetales order p25-alpha PF05517.12 OWF53239.1 - 2.2e-20 73.4 7.1 2.6e-20 73.1 7.1 1.1 1 0 0 1 1 1 1 p25-alpha p25-alpha PF05517.12 OWF53240.1 - 1.1e-27 97.1 2.6 1.3e-27 96.8 2.6 1.1 1 0 0 1 1 1 1 p25-alpha PKD_channel PF08016.12 OWF53241.1 - 2.8e-99 332.7 19.8 5.1e-99 331.8 19.8 1.4 1 0 0 1 1 1 1 Polycystin cation channel REJ PF02010.15 OWF53241.1 - 1e-19 70.7 0.2 2.8e-19 69.2 0.2 1.6 1 0 0 1 1 1 1 REJ domain PLAT PF01477.23 OWF53241.1 - 2.1e-11 44.4 0.0 7e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 OWF53241.1 - 1.5e-10 40.7 28.1 1.5e-10 40.7 28.1 3.4 4 0 0 4 4 4 1 Ion transport protein GPS PF01825.21 OWF53241.1 - 5e-05 23.7 7.2 5e-05 23.7 7.2 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DUF2367 PF10164.9 OWF53241.1 - 0.05 14.1 1.7 2.1 8.9 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) PKD PF00801.20 OWF53243.1 - 1.1e-16 60.5 38.6 0.0019 18.0 4.3 10.2 10 1 0 10 10 10 5 PKD domain WSC PF01822.19 OWF53243.1 - 3.5e-13 49.5 7.5 3.5e-13 49.5 7.5 2.6 2 0 0 2 2 2 1 WSC domain Y_Y_Y PF07495.13 OWF53243.1 - 0.15 12.0 0.8 50 4.0 0.0 4.1 3 0 0 3 3 3 0 Y_Y_Y domain GSHPx PF00255.19 OWF53245.1 - 3.6e-15 55.4 0.2 5e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.6 OWF53245.1 - 0.048 14.1 0.0 0.054 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) GSHPx PF00255.19 OWF53246.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase TYW3 PF02676.14 OWF53247.1 - 1.6e-55 187.8 0.1 2.5e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF3741 PF12552.8 OWF53247.1 - 0.049 13.6 3.3 0.51 10.3 0.3 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3741) MalF_P2 PF14785.6 OWF53249.1 - 0.00019 21.5 7.6 2 8.4 0.7 3.9 1 1 4 5 5 5 5 Maltose transport system permease protein MalF P2 domain zf-C2H2 PF00096.26 OWF53250.1 - 7e-14 51.4 24.3 5.1e-06 26.7 2.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF53250.1 - 2.1e-11 43.7 27.7 9e-09 35.4 1.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF53250.1 - 2.1e-06 28.1 21.6 0.0014 19.3 1.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF53250.1 - 0.0028 17.6 1.0 0.0028 17.6 1.0 2.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF53250.1 - 0.0064 16.8 2.8 0.15 12.4 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF53250.1 - 0.021 15.2 5.7 0.11 13.0 0.3 3.0 2 1 1 3 3 3 0 Zinc-finger of C2H2 type DUF3850 PF12961.7 OWF53250.1 - 0.12 12.5 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3850) zf-H2C2_5 PF13909.6 OWF53250.1 - 0.42 10.4 15.2 0.092 12.5 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-TAZ PF02135.16 OWF53250.1 - 2.2 8.8 8.2 7.3 7.1 8.1 1.8 1 1 1 2 2 2 0 TAZ zinc finger zf-C2H2_aberr PF17017.5 OWF53250.1 - 3 8.0 7.0 4.2 7.5 2.3 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger GATase_5 PF13507.6 OWF53251.1 - 2e-94 315.5 0.0 3.2e-94 314.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OWF53251.1 - 2.6e-34 118.6 0.1 7.1e-18 65.2 0.2 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OWF53251.1 - 2e-15 56.8 0.0 3.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OWF53251.1 - 1.8e-11 44.3 0.1 5.1e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 OWF53251.1 - 0.0012 19.5 0.2 0.02 15.6 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Ank_2 PF12796.7 OWF53252.1 - 2.3e-33 114.6 11.0 3.2e-17 62.9 0.9 4.5 2 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53252.1 - 8e-33 112.4 4.3 7.6e-12 45.5 0.1 5.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF53252.1 - 4.1e-23 78.9 5.4 0.00058 20.1 0.0 9.2 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 OWF53252.1 - 5e-19 67.8 4.3 6.9e-05 23.1 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OWF53252.1 - 3e-16 59.3 8.1 1.1e-06 28.7 0.1 5.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) AAA_22 PF13401.6 OWF53252.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain XPB_DRD PF18458.1 OWF53253.1 - 0.0014 18.5 0.3 27 4.7 0.0 5.6 5 2 1 6 6 6 1 Xeroderma pigmentosum group B helicase damage recognition domain PBCV_basic_adap PF08789.10 OWF53253.1 - 0.0091 16.1 0.0 17 5.6 0.0 5.1 5 0 0 5 5 5 1 PBCV-specific basic adaptor domain DUF4984 PF16372.5 OWF53253.1 - 0.38 10.7 5.1 13 5.7 0.0 4.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4984) DUF3756 PF12581.8 OWF53253.1 - 0.8 9.6 43.3 10 6.1 0.0 10.4 11 0 0 11 11 11 0 Protein of unknown function (DUF3756) IFT57 PF10498.9 OWF53254.1 - 8.1e-151 502.1 18.1 1e-150 501.8 18.1 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 OWF53254.1 - 0.0008 18.4 15.4 0.0008 18.4 15.4 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein DASH_Dad1 PF08649.10 OWF53254.1 - 0.078 13.2 3.1 7.2 6.9 0.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad1 LOH1CR12 PF10158.9 OWF53254.1 - 0.32 11.0 5.6 0.2 11.7 3.3 1.9 1 1 1 2 2 2 0 Tumour suppressor protein SpecificRecomb PF10136.9 OWF53254.1 - 0.64 8.3 5.8 0.83 7.9 5.8 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF1664 PF07889.12 OWF53254.1 - 0.76 9.8 11.8 17 5.5 11.3 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) THF_DHG_CYH PF00763.23 OWF53254.1 - 0.89 9.8 5.0 9 6.6 0.1 3.6 3 1 1 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF4600 PF15372.6 OWF53254.1 - 1 9.8 15.0 0.81 10.1 4.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Exonuc_VII_L PF02601.15 OWF53254.1 - 1.8 8.1 14.2 2.8 7.4 13.6 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 OWF53254.1 - 2.4 8.2 21.7 2.7 8.1 15.2 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 OWF53254.1 - 2.4 7.2 15.7 5.1 6.1 15.7 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 OWF53254.1 - 2.9 7.6 12.5 0.14 11.9 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.11 OWF53254.1 - 3 8.2 5.3 36 4.7 3.1 3.3 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 OWF53254.1 - 4 7.5 10.6 97 3.0 8.9 2.8 2 1 0 2 2 2 0 Laminin Domain II DUF1660 PF07874.11 OWF53255.1 - 0.18 12.3 2.5 0.2 12.2 0.6 2.0 2 1 0 2 2 2 0 Prophage protein (DUF1660) Lipase_GDSL_2 PF13472.6 OWF53256.1 - 0.0086 16.5 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF53256.1 - 0.091 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase GGA_N-GAT PF18308.1 OWF53256.1 - 0.22 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 GGA N-GAT domain Retrotrans_gag PF03732.17 OWF53258.1 - 5.4e-05 23.4 0.9 0.00012 22.3 0.9 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein SCAN PF02023.17 OWF53258.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 SCAN domain Lipoprotein_18 PF06804.11 OWF53258.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Adeno_E4_ORF3 PF06931.11 OWF53260.1 - 0.00027 21.1 8.2 0.47 10.7 0.9 3.7 1 1 3 4 4 4 4 Mastadenovirus E4 ORF3 protein DUF3517 PF12030.8 OWF53260.1 - 0.14 11.0 0.1 0.98 8.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3517) Adeno_E4_ORF3 PF06931.11 OWF53261.1 - 0.00089 19.5 21.9 15 5.8 0.2 6.6 1 1 6 7 7 7 1 Mastadenovirus E4 ORF3 protein Phage_holin_4_2 PF04020.13 OWF53261.1 - 0.017 15.8 9.8 1.4 9.7 1.6 3.8 1 1 2 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV DUF3517 PF12030.8 OWF53261.1 - 0.047 12.6 0.1 4.9 6.0 0.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF3517) TOM13 PF08219.11 OWF53261.1 - 0.1 12.6 10.2 41 4.2 0.1 5.7 3 2 4 7 7 7 0 Outer membrane protein TOM13 LBP_BPI_CETP PF01273.25 OWF53261.1 - 2 8.0 9.4 1.4e+02 2.0 0.1 5.5 1 1 2 3 3 3 0 LBP / BPI / CETP family, N-terminal domain MID_MedPIWI PF18296.1 OWF53261.1 - 2.7 7.7 11.0 74 3.0 0.0 5.8 3 2 4 9 9 9 0 MID domain of medPIWI Hydrophob_seed PF14547.6 OWF53261.1 - 6.4 7.1 18.7 26 5.1 0.5 5.0 2 1 4 6 6 6 0 Hydrophobic seed protein zf-RING_UBOX PF13445.6 OWF53262.1 - 9.8e-09 35.1 2.6 9.8e-09 35.1 2.6 3.6 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF53262.1 - 8.2e-08 32.0 2.1 8.2e-08 32.0 2.1 3.8 4 1 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF53262.1 - 4.7e-06 26.3 2.0 4.7e-06 26.3 2.0 4.0 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF53262.1 - 3.5e-05 23.9 5.0 3.5e-05 23.9 5.0 3.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF53262.1 - 3.8e-05 23.6 2.4 3.8e-05 23.6 2.4 3.6 3 1 0 3 3 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF53262.1 - 4e-05 23.8 2.8 4e-05 23.8 2.8 3.9 3 0 0 3 3 1 1 Ring finger domain NHL PF01436.21 OWF53262.1 - 6.2e-05 22.8 1.8 0.33 11.1 0.0 5.0 5 0 0 5 5 4 1 NHL repeat zf-C3HC4_3 PF13920.6 OWF53262.1 - 0.00014 21.7 3.4 0.00014 21.7 3.4 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF53262.1 - 0.00063 19.4 0.5 0.035 13.7 0.1 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OWF53262.1 - 0.15 12.1 0.8 0.29 11.1 0.8 1.5 1 0 0 1 1 1 0 Beta-propeller repeat Glyco_H_20C_C PF18088.1 OWF53262.1 - 0.16 11.8 4.2 0.26 11.1 4.2 1.3 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain MscS_porin PF12795.7 OWF53262.1 - 0.29 10.7 6.9 0.45 10.0 6.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ANAPC5 PF12862.7 OWF53262.1 - 0.48 10.5 2.1 4.8 7.3 0.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Exonuc_VII_L PF02601.15 OWF53262.1 - 4.6 6.7 8.9 5.5 6.5 7.8 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit zf-B_box PF00643.24 OWF53262.1 - 7 6.9 39.8 1 9.6 13.7 4.3 3 0 0 3 3 3 0 B-box zinc finger zf-RING_UBOX PF13445.6 OWF53263.1 - 4.6e-08 32.9 9.2 4.6e-08 32.9 9.2 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF53263.1 - 1.1e-07 31.6 7.6 1.1e-07 31.6 7.6 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF53263.1 - 3.9e-07 29.9 5.4 3.9e-07 29.9 5.4 3.6 3 1 0 3 3 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF53263.1 - 8e-07 29.3 7.2 8e-07 29.3 7.2 3.8 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF53263.1 - 3.3e-06 27.1 9.3 3.3e-06 27.1 9.3 3.3 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING NHL PF01436.21 OWF53263.1 - 3.4e-06 26.8 7.6 0.011 15.7 0.1 5.2 5 0 0 5 5 5 2 NHL repeat zf-C3HC4_3 PF13920.6 OWF53263.1 - 8.4e-06 25.6 6.0 8.4e-06 25.6 6.0 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF53263.1 - 0.00065 19.5 8.6 0.00065 19.5 8.6 4.4 4 2 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF53263.1 - 0.0022 17.8 5.4 0.0022 17.8 5.4 2.9 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 SBBP PF06739.11 OWF53263.1 - 0.026 14.5 0.1 0.068 13.2 0.1 1.7 1 0 0 1 1 1 0 Beta-propeller repeat SGL PF08450.12 OWF53263.1 - 0.049 13.2 2.0 0.39 10.3 0.6 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region zf-CHC2 PF01807.20 OWF53263.1 - 0.32 10.8 5.4 0.22 11.4 1.7 2.4 1 1 1 2 2 2 0 CHC2 zinc finger DUF3450 PF11932.8 OWF53263.1 - 0.43 9.8 4.5 0.84 8.9 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4587 PF15248.6 OWF53266.1 - 3.4e-08 34.2 23.1 3.4e-08 34.2 23.1 4.3 2 2 2 4 4 4 1 Domain of unknown function (DUF4587) CaM_binding PF07839.11 OWF53266.1 - 0.099 13.4 2.6 0.2 12.4 2.6 1.5 1 0 0 1 1 1 0 Plant calmodulin-binding domain PRIMA1 PF16101.5 OWF53266.1 - 1.6 8.8 7.8 3.4 7.7 3.1 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF2870 PF11069.8 OWF53266.1 - 3.9 7.9 5.7 0.4 11.1 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Caskin-Pro-rich PF16907.5 OWF53266.1 - 6.6 7.3 8.6 3.1 8.4 1.2 2.4 2 0 0 2 2 2 0 Proline rich region of Caskin proteins WD40 PF00400.32 OWF53267.1 - 1.8e-56 186.8 26.5 2.6e-09 37.5 0.8 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.15 OWF53267.1 - 5e-21 74.7 0.0 8.8e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.17 OWF53267.1 - 1.7e-16 60.1 0.0 3.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF53267.1 - 1.1e-15 57.9 0.0 2.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 OWF53267.1 - 1.1e-15 57.7 0.1 0.00019 21.7 0.0 5.6 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF53267.1 - 1.4e-12 47.2 4.3 0.056 12.4 0.1 5.2 1 1 2 5 5 5 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF53267.1 - 5.6e-07 29.6 0.3 0.11 12.3 0.0 3.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OWF53267.1 - 1.1e-05 24.3 3.1 0.056 12.1 0.0 4.5 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Frtz PF11768.8 OWF53267.1 - 9.6e-05 20.9 0.7 0.13 10.5 0.0 3.7 2 2 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz zf-NOSIP PF15906.5 OWF53267.1 - 0.00022 21.3 0.0 0.00081 19.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein WD40_like PF17005.5 OWF53267.1 - 0.00034 20.0 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain zf-RING_UBOX PF13445.6 OWF53267.1 - 0.0032 17.5 0.9 1.2 9.3 0.0 3.0 3 0 0 3 3 3 1 RING-type zinc-finger SAM_PNT PF02198.16 OWF53267.1 - 0.0062 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-Nse PF11789.8 OWF53267.1 - 0.023 14.5 0.0 0.077 12.8 0.0 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit IKI3 PF04762.12 OWF53267.1 - 0.077 11.0 0.0 0.26 9.2 0.0 1.8 2 0 0 2 2 2 0 IKI3 family Bromodomain PF00439.25 OWF53268.1 - 1.8e-20 72.8 0.1 5.1e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 OWF53268.1 - 1.2e-17 63.5 31.7 3.3e-12 46.1 7.5 3.6 3 0 0 3 3 3 2 PHD-finger MBD PF01429.19 OWF53268.1 - 8.9e-12 44.6 0.0 2.3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain WSD PF15613.6 OWF53268.1 - 1.8e-06 28.3 8.1 0.00027 21.3 0.2 6.8 5 2 0 5 5 5 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OWF53268.1 - 0.00019 21.7 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 DDT domain AT_hook PF02178.19 OWF53268.1 - 0.095 12.6 3.8 0.41 10.7 3.8 2.2 1 0 0 1 1 1 0 AT hook motif PHD_2 PF13831.6 OWF53268.1 - 0.23 11.0 9.6 1.3 8.6 1.6 2.7 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 OWF53268.1 - 0.78 10.0 18.4 13 6.2 3.9 3.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain ubiquitin PF00240.23 OWF53269.1 - 8.7e-08 31.8 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family SUIM_assoc PF16619.5 OWF53269.1 - 0.002 18.2 0.0 0.018 15.1 0.0 2.7 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ATP-synt_F PF01990.17 OWF53270.1 - 1.1e-31 108.9 0.1 1.3e-31 108.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit bZIP_1 PF00170.21 OWF53271.1 - 4.8e-13 49.0 3.3 9.1e-13 48.1 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OWF53271.1 - 6.2e-06 26.2 6.3 6.3e-06 26.2 4.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper zf-C2H2 PF00096.26 OWF53271.1 - 7.4e-05 23.0 0.6 0.00015 22.0 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF53271.1 - 0.01 16.6 0.4 0.025 15.4 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger bZIP_Maf PF03131.17 OWF53271.1 - 0.015 15.8 2.9 0.015 15.8 2.9 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF1614 PF07758.11 OWF53271.1 - 1.1 9.2 5.4 2.4 8.1 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) ATP-synt_C PF00137.21 OWF53272.1 - 7e-11 42.3 13.0 1.1e-10 41.7 13.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit C DuoxA PF10204.9 OWF53272.1 - 0.34 9.9 1.8 7.5 5.5 0.0 2.1 2 0 0 2 2 2 0 Dual oxidase maturation factor zf-C2H2_aberr PF17017.5 OWF53273.1 - 2.4e-08 34.3 1.3 3.7e-05 23.9 0.0 3.2 2 1 0 3 3 3 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 OWF53273.1 - 3.6e-08 33.6 13.7 0.0001 22.8 0.9 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF53273.1 - 1.4e-05 25.3 16.5 0.0034 17.8 2.4 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 OWF53273.1 - 6.3e-05 23.5 3.9 0.3 11.8 0.0 3.8 2 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 OWF53273.1 - 0.00078 19.4 6.2 0.016 15.2 0.4 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-BED PF02892.15 OWF53273.1 - 0.0061 16.6 3.0 0.0061 16.6 3.0 2.9 3 0 0 3 3 3 1 BED zinc finger zf-C2H2_3rep PF18868.1 OWF53273.1 - 0.0066 17.1 4.7 1.2 9.8 1.1 2.6 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 OWF53273.1 - 0.019 15.3 5.0 0.57 10.5 0.1 3.4 4 0 0 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding Zf_RING PF16744.5 OWF53273.1 - 0.084 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C2H2_jaz PF12171.8 OWF53273.1 - 0.093 13.0 0.5 0.093 13.0 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OWF53273.1 - 0.15 12.6 10.6 3.1 8.4 1.4 3.7 3 0 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 OWF53273.1 - 0.25 9.8 3.5 1.3 7.5 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 OWF53273.1 - 0.59 10.5 7.3 0.78 10.1 3.5 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 OWF53273.1 - 2.9 7.8 4.9 29 4.6 0.0 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 OWF53273.1 - 6.7 6.6 10.1 1.1 9.0 3.3 2.9 3 0 0 3 3 2 0 C2H2-type zinc-finger domain DUF5633 PF18656.1 OWF53274.1 - 0.33 10.9 1.0 20 5.2 0.1 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5633) Phage_Orf51 PF06194.11 OWF53274.1 - 0.36 10.9 2.3 0.6 10.2 0.9 1.8 1 1 1 2 2 2 0 Phage Conserved Open Reading Frame 51 Acyl-ACP_TE PF01643.17 OWF53275.1 - 2e-09 37.1 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 OWF53275.1 - 0.00011 22.7 0.3 0.31 11.5 0.1 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily ERM PF00769.19 OWF53276.1 - 0.0023 17.8 6.0 0.0028 17.5 6.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YabA PF06156.13 OWF53276.1 - 0.0031 18.1 3.2 0.0051 17.4 3.2 1.5 1 1 0 1 1 1 1 Initiation control protein YabA TPR_MLP1_2 PF07926.12 OWF53276.1 - 0.038 14.1 4.8 1 9.5 0.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 OWF53276.1 - 0.056 13.5 2.3 0.11 12.6 2.3 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Metal_resist PF13801.6 OWF53276.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Allexi_40kDa PF05549.11 OWF53276.1 - 0.26 10.8 4.5 0.34 10.4 4.2 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein PIEZO PF15917.5 OWF53276.1 - 0.29 10.6 4.1 0.36 10.3 4.1 1.2 1 0 0 1 1 1 0 Piezo C1q PF00386.21 OWF53277.1 - 9.3e-22 77.6 0.8 1.7e-21 76.7 0.8 1.5 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF53277.1 - 6.5e-05 22.8 0.7 0.00011 22.2 0.7 1.3 1 0 0 1 1 1 1 BclA C-terminal domain ERM PF00769.19 OWF53277.1 - 0.0023 17.8 3.7 0.003 17.4 3.7 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YabA PF06156.13 OWF53277.1 - 0.0023 18.5 1.3 0.0055 17.3 1.3 1.6 1 0 0 1 1 1 1 Initiation control protein YabA Spc7 PF08317.11 OWF53277.1 - 0.034 13.0 1.6 0.055 12.3 1.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 OWF53277.1 - 0.066 13.3 3.3 0.13 12.4 3.3 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Atg14 PF10186.9 OWF53277.1 - 0.07 12.2 1.0 0.1 11.7 1.0 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNase PF00565.17 OWF53277.1 - 0.092 13.2 0.2 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Staphylococcal nuclease homologue TPR_MLP1_2 PF07926.12 OWF53277.1 - 0.12 12.4 4.7 1.7 8.7 0.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Allexi_40kDa PF05549.11 OWF53277.1 - 1.6 8.2 4.9 1.2 8.6 3.2 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein C1q PF00386.21 OWF53278.1 - 2.5e-20 73.0 0.7 4.6e-20 72.1 0.7 1.4 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF53278.1 - 9.7e-05 22.3 1.3 0.00016 21.6 0.6 1.7 1 1 0 1 1 1 1 BclA C-terminal domain YabA PF06156.13 OWF53278.1 - 0.0027 18.3 0.9 0.005 17.5 0.9 1.4 1 0 0 1 1 1 1 Initiation control protein YabA ERM PF00769.19 OWF53278.1 - 0.0047 16.8 2.8 0.0064 16.3 2.8 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CtIP_N PF10482.9 OWF53278.1 - 0.013 15.5 0.9 0.025 14.6 0.9 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Metal_resist PF13801.6 OWF53278.1 - 0.041 14.1 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance TPR_MLP1_2 PF07926.12 OWF53278.1 - 0.067 13.3 2.2 1.5 8.9 0.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IL2 PF00715.17 OWF53278.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Interleukin 2 C1q PF00386.21 OWF53279.1 - 1.5e-21 76.9 0.1 2.3e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 C1q domain YabA PF06156.13 OWF53279.1 - 0.0016 19.1 0.1 0.0028 18.3 0.1 1.4 1 0 0 1 1 1 1 Initiation control protein YabA BclA_C PF18573.1 OWF53279.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 BclA C-terminal domain Use1 PF09753.9 OWF53279.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Taxilin PF09728.9 OWF53279.1 - 0.037 13.2 0.5 0.052 12.7 0.5 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Herpes_UL6 PF01763.16 OWF53279.1 - 0.042 12.4 0.3 0.06 11.9 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like TPR_MLP1_2 PF07926.12 OWF53279.1 - 0.06 13.4 0.6 8.8 6.4 0.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OWF53279.1 - 0.062 12.2 0.6 0.099 11.5 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 OWF53279.1 - 0.1 12.7 0.5 0.77 9.9 0.2 2.1 1 1 1 2 2 2 0 bZIP transcription factor ATG16 PF08614.11 OWF53279.1 - 0.12 12.6 1.4 0.2 11.9 1.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 OWF53279.1 - 0.17 11.9 0.8 0.27 11.3 0.8 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 OWF53279.1 - 0.18 11.6 0.8 0.73 9.6 0.3 2.1 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 OWF53279.1 - 0.18 12.3 0.6 0.32 11.5 0.2 1.6 1 1 1 2 2 2 0 Cell division protein ZapB CASP_C PF08172.12 OWF53279.1 - 0.19 11.0 0.6 0.3 10.4 0.4 1.3 1 1 0 1 1 1 0 CASP C terminal 7tm_1 PF00001.21 OWF53280.1 - 3.8e-65 219.8 5.9 3.2e-64 216.8 5.9 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF53280.1 - 1.3e-16 60.8 13.8 7.5e-13 48.5 8.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF53280.1 - 7.4e-11 42.2 10.5 7.4e-11 42.2 10.5 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF53280.1 - 1.4e-05 25.0 4.3 1.4e-05 25.0 4.3 2.1 2 1 0 2 2 2 1 Olfactory receptor CitMHS PF03600.16 OWF53280.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Citrate transporter GPDPase_memb PF10110.9 OWF53280.1 - 0.11 11.2 11.1 0.075 11.8 0.5 2.7 3 0 0 3 3 3 0 Membrane domain of glycerophosphoryl diester phosphodiesterase STAG PF08514.11 OWF53280.1 - 1.1 9.2 8.0 12 5.9 2.9 2.4 2 0 0 2 2 2 0 STAG domain Peptidase_S49_N PF08496.10 OWF53280.1 - 1.6 8.7 5.8 5 7.2 0.0 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Syntaxin-18_N PF10496.9 OWF53280.1 - 2.6 8.4 5.9 0.3 11.3 0.5 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Lectin_C PF00059.21 OWF53281.1 - 0.00055 20.6 0.5 0.00092 19.9 0.5 1.4 1 1 0 1 1 1 1 Lectin C-type domain WSC PF01822.19 OWF53281.1 - 0.041 14.1 0.2 0.041 14.1 0.2 1.7 2 0 0 2 2 2 0 WSC domain SKG6 PF08693.10 OWF53283.1 - 0.028 13.8 0.9 0.05 13.0 0.9 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PGF-CTERM PF18204.1 OWF53283.1 - 0.31 11.1 0.2 0.31 11.1 0.2 1.5 2 0 0 2 2 2 0 PGF-CTERM motif YEATS PF03366.16 OWF53284.1 - 2.7e-24 84.9 0.6 5.9e-24 83.8 0.6 1.6 1 0 0 1 1 1 1 YEATS family ABC_membrane PF00664.23 OWF53286.1 - 2.8e-72 243.7 26.2 2.2e-42 145.6 9.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF53286.1 - 3.7e-54 183.0 0.0 5.4e-30 104.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF53286.1 - 7.1e-10 38.7 3.5 0.19 11.1 0.1 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OWF53286.1 - 4e-07 30.2 1.9 0.071 12.9 0.2 4.3 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OWF53286.1 - 4.2e-06 26.4 0.2 0.026 14.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OWF53286.1 - 8.2e-06 25.9 0.1 0.19 11.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 OWF53286.1 - 0.00011 22.4 0.2 0.51 10.4 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 OWF53286.1 - 0.00019 21.4 0.5 0.02 14.8 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OWF53286.1 - 0.00025 21.5 0.8 0.036 14.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OWF53286.1 - 0.00081 20.0 0.2 1.7 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OWF53286.1 - 0.0021 18.3 0.1 0.43 10.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OWF53286.1 - 0.0093 16.3 0.2 7.3 7.0 0.0 3.8 3 0 0 3 3 3 1 RNA helicase MeaB PF03308.16 OWF53286.1 - 0.0096 14.9 0.0 0.51 9.3 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OWF53286.1 - 0.019 15.0 1.6 0.25 11.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 OWF53286.1 - 0.02 14.2 0.2 2.6 7.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 OWF53286.1 - 0.022 14.5 0.1 0.39 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 OWF53286.1 - 0.027 15.0 0.0 0.37 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OWF53286.1 - 0.032 13.2 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 OWF53286.1 - 0.042 14.1 0.3 10 6.4 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 OWF53286.1 - 0.057 12.6 0.1 3.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OWF53286.1 - 0.086 12.6 0.0 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 OWF53286.1 - 0.39 10.6 1.7 2.1 8.2 0.0 2.5 3 0 0 3 3 2 0 NACHT domain Glyco_transf_25 PF01755.17 OWF53287.1 - 0.01 15.7 0.9 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Astacin PF01400.24 OWF53288.1 - 2.3e-59 200.2 0.0 3.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 OWF53288.1 - 4.6e-26 91.3 0.0 9.2e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 CUB domain Peptidase_M10 PF00413.24 OWF53288.1 - 0.017 15.0 1.9 1.8 8.4 0.5 2.6 3 0 0 3 3 3 0 Matrixin LRR_6 PF13516.6 OWF53289.1 - 3.6e-30 101.4 11.8 4.1e-05 23.3 0.0 8.6 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 OWF53289.1 - 0.0001 22.4 0.6 8.2 7.4 0.0 6.9 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 OWF53289.1 - 0.0011 19.3 7.4 1.8 9.1 0.1 5.2 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF53289.1 - 0.0045 16.7 8.2 0.15 11.8 0.2 4.8 5 2 1 6 6 6 3 Leucine rich repeat Pro_isomerase PF00160.21 OWF53291.1 - 9.7e-45 152.7 0.1 1.2e-44 152.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Wza_C PF18412.1 OWF53292.1 - 7.8e-10 38.3 2.6 16 5.3 0.0 6.6 6 0 0 6 6 6 6 Outer-membrane lipoprotein Wza C-terminal domain NfI_DNAbd_pre-N PF10524.9 OWF53292.1 - 7.1e-09 35.4 26.5 0.45 10.4 0.1 8.4 1 1 4 7 7 7 5 Nuclear factor I protein pre-N-terminus Cuticle_3 PF11018.8 OWF53292.1 - 4.7e-05 23.7 0.0 0.31 11.3 0.0 2.8 1 1 1 3 3 3 2 Pupal cuticle protein C1 Cyclin_C_2 PF16899.5 OWF53292.1 - 8.3e-05 22.9 0.0 3.2 8.2 0.0 4.7 1 1 3 4 4 4 2 Cyclin C-terminal domain DUF2164 PF09932.9 OWF53292.1 - 0.024 14.7 0.0 12 6.0 0.0 3.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2164) DUF668 PF05003.12 OWF53292.1 - 0.15 12.5 0.0 6.8 7.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF668) Drf_FH1 PF06346.12 OWF53292.1 - 2.2 8.0 8.0 3.6 7.3 8.0 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 GD_N PF16030.5 OWF53292.1 - 4.8 7.5 7.3 1.4e+02 2.8 0.1 4.1 3 2 2 5 5 5 0 Serine protease gd N-terminus Ig_3 PF13927.6 OWF53293.1 - 2.6e-25 88.8 10.8 9.5e-07 29.3 0.2 4.3 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 OWF53293.1 - 1e-20 73.6 9.0 2.4e-05 24.3 0.1 6.2 4 3 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF53293.1 - 1.1e-19 70.5 14.1 6.6e-05 23.2 0.5 4.1 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 OWF53293.1 - 2e-08 34.3 9.2 0.049 13.8 0.1 4.7 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 OWF53293.1 - 1.8e-07 31.3 14.5 0.3 11.3 0.1 5.5 4 2 2 6 6 6 3 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF53293.1 - 2.9e-07 30.6 4.6 0.11 12.7 0.1 3.3 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 OWF53293.1 - 7.4e-05 22.2 0.1 4.1 7.0 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Receptor_2B4 PF11465.8 OWF53293.1 - 0.001 19.2 0.1 0.34 11.1 0.0 2.7 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 OWF53293.1 - 0.0014 18.6 1.0 3.4 7.7 0.0 3.1 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain Peptidase_S9_N PF02897.15 OWF53293.1 - 0.0026 16.6 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Invasin_D3 PF09134.10 OWF53293.1 - 0.012 15.9 1.9 0.17 12.2 0.1 3.0 3 0 0 3 3 3 0 Invasin, domain 3 SH2 PF00017.24 OWF53293.1 - 0.087 12.9 0.3 21 5.3 0.0 3.5 3 0 0 3 3 3 0 SH2 domain DUF4333 PF14230.6 OWF53293.1 - 0.12 12.7 1.2 0.31 11.3 0.5 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4333) Ig_C17orf99 PF17736.1 OWF53293.1 - 0.53 10.4 2.9 5.7 7.0 0.0 3.4 5 0 0 5 5 5 0 C17orf99 Ig domain Adeno_E3_CR1 PF02440.15 OWF53293.1 - 1 9.2 10.6 11 5.8 0.1 4.2 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Enterotoxin_ST PF02048.16 OWF53293.1 - 2.1 8.9 9.9 27 5.3 1.0 3.7 3 0 0 3 3 3 0 Heat-stable enterotoxin ST MBG_2 PF18676.1 OWF53293.1 - 6.1 7.6 9.0 4.1 8.1 0.2 3.2 4 0 0 4 4 3 0 MBG domain (YGX type) 7tm_1 PF00001.21 OWF53294.1 - 1.6e-45 155.5 19.9 2.1e-45 155.1 19.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF53294.1 - 9.5e-11 41.6 22.7 1.4e-10 41.0 22.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF53294.1 - 0.37 10.4 26.2 0.28 10.8 22.3 2.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx GPP34 PF05719.11 OWF53295.1 - 2e-59 201.1 0.7 2.3e-59 200.9 0.7 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Ig_2 PF13895.6 OWF53297.1 - 2.5e-06 27.7 0.2 7.5e-06 26.2 0.0 1.8 1 1 1 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 OWF53297.1 - 2.3e-05 24.4 0.3 6e-05 23.0 0.1 1.8 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 OWF53297.1 - 7.2e-05 23.3 0.7 0.00023 21.7 0.2 2.0 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.25 OWF53297.1 - 0.0077 16.4 0.1 0.025 14.7 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain tRNA_edit PF04073.15 OWF53298.1 - 0.099 12.7 10.5 4.3 7.4 0.1 4.6 1 1 2 4 4 4 0 Aminoacyl-tRNA editing domain Colipase-like PF15083.6 OWF53298.1 - 0.12 12.6 23.2 0.53 10.4 8.7 2.6 1 1 2 3 3 3 0 Colipase-like RRM_occluded PF16842.5 OWF53298.1 - 0.13 12.2 16.7 21 5.0 1.2 5.7 1 1 5 6 6 6 0 Occluded RNA-recognition motif YbfN PF13982.6 OWF53298.1 - 0.46 10.8 20.6 17 5.8 0.4 5.6 1 1 5 6 6 6 0 YbfN-like lipoprotein PV-1 PF06637.11 OWF53298.1 - 0.63 8.8 29.4 0.72 8.6 13.9 2.8 1 1 1 2 2 2 0 PV-1 protein (PLVAP) DUF370 PF04025.12 OWF53298.1 - 0.69 10.1 30.2 1.6 8.9 3.1 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF370) DUF5103 PF17116.5 OWF53298.1 - 2.2 7.5 5.7 3.5 6.8 1.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5103) DUF5301 PF17225.3 OWF53298.1 - 6.4 7.3 20.9 3.3 8.2 0.8 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5300) ACP53EA PF06313.11 OWF53298.1 - 8.9 6.6 32.5 13 6.1 4.8 4.3 1 1 3 4 4 4 0 Drosophila ACP53EA protein fn3 PF00041.21 OWF53299.1 - 2.6e-116 380.2 55.0 1.3e-12 47.8 0.3 12.4 12 0 0 12 12 12 12 Fibronectin type III domain Interfer-bind PF09294.10 OWF53299.1 - 2.5e-19 69.5 16.7 0.015 15.6 0.2 11.5 12 1 0 12 12 12 5 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 OWF53299.1 - 8e-19 68.0 52.1 0.02 15.5 0.8 13.2 11 3 0 11 11 11 8 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 OWF53299.1 - 1.1e-09 38.7 4.4 1.2e-09 38.7 0.1 3.5 4 0 0 4 4 3 1 Immunoglobulin domain I-set PF07679.16 OWF53299.1 - 8.3e-09 35.4 0.0 2.2e-07 30.8 0.0 3.5 3 0 0 3 3 2 1 Immunoglobulin I-set domain TSP_1 PF00090.19 OWF53299.1 - 2e-07 31.1 5.9 4e-07 30.1 5.9 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain ig PF00047.25 OWF53299.1 - 1.7e-06 28.1 0.0 1.3e-05 25.2 0.0 2.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF53299.1 - 2.1e-06 28.0 0.1 2.2e-05 24.7 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain DUF2369 PF10179.9 OWF53299.1 - 5.4e-06 26.7 22.3 4 7.9 0.0 9.7 12 0 0 12 12 12 1 Uncharacterised conserved protein (DUF2369) V-set PF07686.17 OWF53299.1 - 0.0025 17.9 0.0 0.019 15.2 0.0 2.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Glyco_hydro_36C PF16874.5 OWF53299.1 - 0.0033 17.9 0.0 54 4.4 0.0 6.0 8 0 0 8 8 7 0 Glycosyl hydrolase family 36 C-terminal domain DUF1002 PF06207.11 OWF53299.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) WIF PF02019.18 OWF53299.1 - 0.044 13.5 0.2 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 WIF domain Arylsulfotran_N PF17425.2 OWF53299.1 - 0.085 12.9 10.2 1.4 9.0 0.3 4.8 4 0 0 4 4 4 0 Arylsulfotransferase Ig-like domain DUF5001 PF16392.5 OWF53299.1 - 0.26 11.2 1.9 4.5 7.2 0.0 3.8 3 1 1 4 4 4 0 Ig-like domain SRP19 PF01922.17 OWF53300.1 - 5.4e-24 85.0 0.0 9.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein CCDC24 PF15669.5 OWF53300.1 - 0.096 12.5 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Retrotrans_gag PF03732.17 OWF53301.1 - 0.0053 17.0 0.1 0.0083 16.4 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein GNT-I PF03071.15 OWF53302.1 - 4.1e-153 510.2 2.4 4.7e-153 510.0 2.4 1.0 1 0 0 1 1 1 1 GNT-I family GNT-I PF03071.15 OWF53303.1 - 9.2e-138 459.6 1.6 1.6e-137 458.8 1.6 1.3 1 1 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 OWF53303.1 - 0.004 17.1 0.2 0.058 13.3 0.2 2.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF53303.1 - 0.028 14.2 0.1 6.8 6.5 0.1 3.0 3 0 0 3 3 3 0 Glycosyl transferase family 2 KIAA1328 PF15369.6 OWF53304.1 - 7.3e-26 91.8 21.9 1.6e-22 80.8 9.9 2.5 2 0 0 2 2 2 2 Uncharacterised protein KIAA1328 Sulf_transp PF04143.14 OWF53305.1 - 8.8e-41 140.5 22.2 1.2e-40 140.0 22.2 1.2 1 0 0 1 1 1 1 Sulphur transport ROQ_II PF18386.1 OWF53306.1 - 0.55 10.1 21.5 2.1e+02 1.9 0.0 13.6 13 7 7 20 20 20 0 Roquin II domain Fascin PF06268.13 OWF53307.1 - 9e-06 25.9 3.2 0.53 10.5 0.3 3.9 1 1 4 5 5 5 5 Fascin domain DUF5622 PF18533.1 OWF53307.1 - 0.095 12.9 1.6 41 4.4 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5622) TraA PF05513.11 OWF53307.1 - 0.11 12.9 10.1 14 6.1 0.2 4.6 1 1 2 4 4 4 0 TraA Herpes_UL42 PF02282.16 OWF53307.1 - 4.2 7.2 28.1 7.2 6.5 8.0 4.1 1 1 3 4 4 4 0 DNA polymerase processivity factor (UL42) DUF1071 PF06378.11 OWF53307.1 - 5.6 6.5 16.8 5.7 6.5 0.9 3.3 1 1 0 3 3 3 0 Protein of unknown function (DUF1071) CbtA PF09490.10 OWF53308.1 - 0.023 14.5 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) TMEM154 PF15102.6 OWF53309.1 - 0.012 15.5 1.4 0.028 14.3 1.4 1.5 1 0 0 1 1 1 0 TMEM154 protein family MGC-24 PF05283.11 OWF53309.1 - 0.036 14.5 1.7 0.081 13.4 1.7 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MgtE PF01769.16 OWF53309.1 - 0.056 13.8 0.9 0.1 12.9 0.9 1.4 1 0 0 1 1 1 0 Divalent cation transporter TMEM89 PF15098.6 OWF53309.1 - 0.11 12.7 4.4 0.29 11.3 0.2 2.2 2 0 0 2 2 2 0 TMEM89 protein family Syndecan PF01034.20 OWF53309.1 - 1.3 9.0 3.6 2.8 7.9 3.6 1.6 1 0 0 1 1 1 0 Syndecan domain C1q PF00386.21 OWF53310.1 - 1.6e-23 83.3 0.2 2.9e-23 82.5 0.0 1.5 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF53310.1 - 4.3e-05 23.4 0.1 7.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 BclA C-terminal domain Serine_rich PF08824.10 OWF53310.1 - 0.0012 18.9 0.7 0.0017 18.4 0.7 1.2 1 0 0 1 1 1 1 Serine rich protein interaction domain YabA PF06156.13 OWF53310.1 - 0.05 14.2 4.7 0.084 13.5 4.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA COMP PF11598.8 OWF53310.1 - 0.51 10.8 4.7 0.36 11.3 0.5 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein FAM76 PF16046.5 OWF53310.1 - 0.69 9.2 3.0 0.92 8.8 3.0 1.1 1 0 0 1 1 1 0 FAM76 protein VWA PF00092.28 OWF53311.1 - 4.5e-114 378.7 6.5 7.2e-38 130.6 0.1 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 OWF53311.1 - 4.8e-46 155.8 0.3 8.3e-14 52.1 0.1 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 OWF53311.1 - 1.3e-14 54.4 0.0 3.5e-05 23.8 0.0 3.5 3 0 0 3 3 3 3 von Willebrand factor type A domain Copine PF07002.16 OWF53311.1 - 0.071 12.6 0.2 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Copine DUF4754 PF15946.5 OWF53311.1 - 0.12 12.7 0.1 6.7 7.1 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4754) ClpB_D2-small PF10431.9 OWF53311.1 - 0.16 12.0 0.0 17 5.6 0.0 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Rabaptin PF03528.15 OWF53312.1 - 1e-81 275.1 51.1 2.1e-44 152.1 18.1 3.2 3 0 0 3 3 3 3 Rabaptin OmpH PF03938.14 OWF53312.1 - 0.02 15.2 6.5 0.02 15.2 6.5 4.6 1 1 4 5 5 5 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 OWF53312.1 - 6 6.9 13.5 12 5.9 3.1 4.1 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L11 PF00298.19 OWF53312.1 - 9.8 6.8 7.6 24 5.5 0.3 3.8 2 1 1 3 3 3 0 Ribosomal protein L11, RNA binding domain Sec1 PF00995.23 OWF53313.1 - 1.5e-85 288.6 2.7 1.8e-85 288.3 2.7 1.0 1 0 0 1 1 1 1 Sec1 family Dynactin_p22 PF07426.11 OWF53314.1 - 1.9e-45 154.8 6.1 2.1e-45 154.6 6.1 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 Sec34 PF04136.15 OWF53314.1 - 0.001 19.0 7.0 0.011 15.6 2.3 2.4 1 1 1 2 2 2 2 Sec34-like family MethyltransfD12 PF02086.15 OWF53314.1 - 0.031 14.0 1.4 0.052 13.2 1.4 1.5 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF2408 PF10303.9 OWF53314.1 - 0.066 13.8 2.4 0.32 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) TraG_N PF07916.11 OWF53314.1 - 0.083 11.7 3.9 0.1 11.4 3.9 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region LXG PF04740.12 OWF53314.1 - 0.097 12.4 12.2 0.31 10.7 3.9 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Occludin_ELL PF07303.13 OWF53314.1 - 0.42 11.4 4.3 1.9 9.3 0.6 2.5 1 1 2 3 3 3 0 Occludin homology domain DUF948 PF06103.11 OWF53314.1 - 0.45 10.8 4.0 0.46 10.8 0.7 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) La PF05383.17 OWF53315.1 - 3.2e-23 81.5 0.8 5.9e-23 80.7 0.8 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OWF53315.1 - 0.0032 17.3 0.1 0.71 9.7 0.1 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 OWF53315.1 - 0.0063 16.5 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 SUZ-C motif TFIIF_alpha PF05793.12 OWF53315.1 - 0.7 8.4 24.1 0.02 13.5 17.9 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 OWF53315.1 - 2.4 6.4 7.5 3.8 5.7 7.5 1.4 1 0 0 1 1 1 0 CDC45-like protein SOG2 PF10428.9 OWF53315.1 - 5.1 6.2 16.9 7.7 5.6 16.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short_C2 PF13561.6 OWF53316.1 - 1.1e-55 188.8 0.1 1.2e-55 188.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF53316.1 - 7.8e-43 146.2 0.3 9.2e-43 146.0 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OWF53316.1 - 1e-05 25.1 0.0 2.6e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OWF53316.1 - 1.5e-05 25.0 0.1 2.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OWF53316.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OWF53316.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain PapC_N PF13954.6 OWF53316.1 - 0.023 14.7 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 PapC N-terminal domain Fe-ADH_2 PF13685.6 OWF53316.1 - 0.03 14.0 0.5 0.041 13.6 0.5 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Oxidored_nitro PF00148.19 OWF53316.1 - 0.036 12.8 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase YqaJ PF09588.10 OWF53317.1 - 4e-15 56.3 0.0 5.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain RNA_GG_bind PF10258.9 OWF53318.1 - 1.3e-27 95.7 0.0 2.9e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain OCC1 PF15506.6 OWF53318.1 - 0.068 13.3 0.6 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 OCC1 family B9-C2 PF07162.11 OWF53319.1 - 1.8e-53 181.2 0.0 2.1e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein 7tm_1 PF00001.21 OWF53320.1 - 1.8e-32 112.7 6.9 2.9e-32 112.1 6.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF53320.1 - 4.5e-11 42.6 7.6 6.7e-11 42.1 7.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF53320.1 - 2.4e-07 30.6 10.2 4.8e-07 29.7 10.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF53320.1 - 6.3e-07 29.4 4.1 6.3e-07 29.4 4.1 1.7 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 OWF53320.1 - 0.00037 20.1 7.0 0.00074 19.1 7.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2614 PF11023.8 OWF53320.1 - 5.1 7.2 6.6 0.86 9.7 0.2 2.6 2 1 1 3 3 3 0 Zinc-ribbon containing domain Ribosomal_L18 PF17135.4 OWF53321.1 - 4.8e-94 313.0 5.7 5.3e-94 312.9 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OWF53321.1 - 0.05 14.3 0.2 0.14 12.8 0.2 1.9 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ATR13 PF16829.5 OWF53321.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector DAGK_cat PF00781.24 OWF53322.1 - 2.6e-25 88.5 0.0 4.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 OWF53322.1 - 0.031 13.1 0.0 0.089 11.6 0.0 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 NDK PF00334.19 OWF53324.1 - 1.4e-39 135.2 0.0 1.9e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 OWF53324.1 - 1.3e-18 66.4 0.3 2e-18 65.8 0.3 1.3 1 0 0 1 1 1 1 Dpy-30 motif V-SNARE PF05008.15 OWF53325.1 - 1.1e-21 77.0 2.9 1.1e-21 77.0 2.9 2.3 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OWF53325.1 - 5.5e-20 71.4 3.7 1.4e-18 66.9 4.3 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OWF53325.1 - 0.002 18.0 0.2 0.002 18.0 0.2 2.4 2 1 0 2 2 2 1 Sec20 Lipoprotein_2 PF00921.17 OWF53325.1 - 0.0044 16.6 0.1 0.0053 16.4 0.1 1.1 1 0 0 1 1 1 1 Borrelia lipoprotein DUF4064 PF13273.6 OWF53325.1 - 0.0085 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Insulin_TMD PF17870.1 OWF53325.1 - 0.017 15.2 3.5 0.03 14.4 3.5 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SbsC_C PF18058.1 OWF53325.1 - 0.034 14.4 1.6 0.085 13.1 0.5 2.0 1 1 1 2 2 2 0 SbsC C-terminal domain Focal_AT PF03623.13 OWF53325.1 - 0.038 14.0 0.7 0.074 13.0 0.7 1.6 1 1 0 1 1 1 0 Focal adhesion targeting region DUF241 PF03087.14 OWF53325.1 - 0.039 13.8 3.9 0.074 12.9 0.5 2.2 2 0 0 2 2 2 0 Arabidopsis protein of unknown function 7TMR-HDED PF07697.11 OWF53325.1 - 0.055 13.6 3.1 0.069 13.3 3.1 1.1 1 0 0 1 1 1 0 7TM-HD extracellular DUF2730 PF10805.8 OWF53325.1 - 0.089 12.9 1.5 0.43 10.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Sec8_exocyst PF04048.14 OWF53325.1 - 0.13 12.1 3.4 4.2 7.3 0.1 2.7 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF4407 PF14362.6 OWF53325.1 - 0.14 11.5 5.4 0.23 10.8 5.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OWF53325.1 - 0.17 11.4 9.8 0.69 9.4 9.8 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit FTCD_C PF04961.12 OWF53325.1 - 0.23 11.2 0.6 0.69 9.6 0.3 1.8 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Mt_ATP-synt_D PF05873.12 OWF53325.1 - 0.27 11.1 3.9 0.5 10.2 2.4 2.2 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) BLOC1_2 PF10046.9 OWF53325.1 - 0.38 11.1 6.1 0.68 10.3 0.6 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.16 OWF53325.1 - 0.61 10.3 7.9 0.37 11.0 0.6 2.5 1 1 2 3 3 3 0 Flagellar FliJ protein Wzz PF02706.15 OWF53325.1 - 1.1 9.6 4.2 0.74 10.2 1.5 2.1 2 1 0 2 2 2 0 Chain length determinant protein YqjK PF13997.6 OWF53325.1 - 1.5 9.1 3.9 2.9 8.2 0.3 2.6 2 1 0 2 2 2 0 YqjK-like protein PilJ PF13675.6 OWF53325.1 - 1.9 8.5 7.1 22 5.1 0.2 2.9 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term L31 PF09784.9 OWF53325.1 - 2.1 8.8 5.5 0.36 11.3 0.5 2.2 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 Syntaxin-6_N PF09177.11 OWF53325.1 - 5.5 7.6 8.1 92 3.7 8.1 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Ribosomal_L34e PF01199.18 OWF53326.1 - 5.1e-44 148.5 4.4 6.3e-44 148.2 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e HlyIII PF03006.20 OWF53327.1 - 3.3e-20 72.8 21.6 4.3e-20 72.4 21.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2842 PF11003.8 OWF53327.1 - 7.3 6.9 14.4 0.5 10.7 2.7 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2842) DIL PF01843.19 OWF53328.1 - 2e-19 69.8 0.1 4.2e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 DIL domain RA PF00788.23 OWF53328.1 - 4e-12 46.6 0.0 1e-11 45.3 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 OWF53328.1 - 7.8e-12 45.4 0.1 2.7e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 OWF53328.1 - 9.2e-10 38.2 0.0 2.6e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain 2OG-FeII_Oxy_3 PF13640.6 OWF53329.1 - 9.4e-09 36.1 0.2 1.7e-07 32.0 0.1 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OWF53329.1 - 0.00094 19.8 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 OWF53329.1 - 0.18 11.3 0.1 0.43 10.1 0.1 1.7 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA FAM195 PF14799.6 OWF53330.1 - 2.7e-12 46.9 0.8 3.9e-12 46.4 0.8 1.2 1 0 0 1 1 1 1 FAM195 family DUF938 PF06080.12 OWF53331.1 - 7.2e-72 241.4 0.0 8.6e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 OWF53331.1 - 0.016 15.9 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 OWF53331.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 OWF53331.1 - 0.16 12.7 0.0 0.28 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Thioredoxin PF00085.20 OWF53332.1 - 1.8e-25 88.9 0.2 3.9e-15 55.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OWF53332.1 - 1e-07 32.1 3.4 0.00054 19.9 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OWF53332.1 - 6.2e-05 23.1 0.1 0.018 15.2 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 OWF53332.1 - 9.6e-05 22.6 0.1 1.1 9.7 0.0 3.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OWF53332.1 - 0.39 11.2 5.1 1.8 9.1 0.1 3.9 4 1 0 4 4 4 0 Thioredoxin-like domain YkuD_2 PF13645.6 OWF53333.1 - 0.067 12.6 0.1 19 4.7 0.0 3.2 1 1 1 3 3 3 0 L,D-transpeptidase catalytic domain Synapsin_N PF10581.9 OWF53333.1 - 0.22 11.5 10.8 1.2e+02 2.7 0.1 6.4 7 0 0 7 7 7 0 Synapsin N-terminal DUF4948 PF16306.5 OWF53333.1 - 1.4 8.7 3.5 9 6.1 0.2 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4948) Meis_PKNOX_N PF16493.5 OWF53334.1 - 2.4e-43 146.4 0.4 4.6e-43 145.5 0.4 1.5 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 OWF53334.1 - 1.6e-20 72.7 1.0 2.8e-20 71.9 1.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF53334.1 - 2.3e-08 33.7 0.4 5.6e-08 32.5 0.4 1.6 1 0 0 1 1 1 1 Homeodomain SSF PF00474.17 OWF53335.1 - 7.8e-37 127.1 20.5 7.8e-37 127.1 20.5 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family TM2 PF05154.16 OWF53336.1 - 2e-48 162.5 53.8 1.4e-13 50.9 3.6 4.2 4 0 0 4 4 4 4 TM2 domain EloA-BP1 PF15870.5 OWF53339.1 - 0.13 12.5 0.3 29 4.9 0.0 3.7 2 2 1 4 4 4 0 ElonginA binding-protein 1 DUF3425 PF11905.8 OWF53339.1 - 8.8 6.3 6.3 53 3.8 2.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3425) FANCI_HD1 PF14679.6 OWF53340.1 - 0.001 19.0 3.0 6.1 6.9 0.0 5.3 5 2 0 5 5 5 2 FANCI helical domain 1 EpCAM_N PF18635.1 OWF53340.1 - 4.6 7.5 23.2 37 4.6 0.1 10.4 9 0 0 9 9 9 0 Epithelial cell adhesion molecule N-terminal domain BTB PF00651.31 OWF53341.1 - 1.9e-29 102.1 0.2 4.4e-28 97.7 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain PHR PF08005.12 OWF53341.1 - 4.9e-13 50.0 0.3 2e-11 44.8 0.2 2.5 2 0 0 2 2 2 1 PHR domain BACK PF07707.15 OWF53341.1 - 2.3e-11 43.7 0.1 2.2e-10 40.5 0.0 2.6 2 1 0 2 2 2 1 BTB And C-terminal Kelch zf-FLZ PF04570.14 OWF53341.1 - 0.025 14.1 0.2 5.7 6.5 0.0 2.6 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 zf-P11 PF03854.14 OWF53341.1 - 6.9 6.4 6.0 0.74 9.5 0.2 2.4 3 0 0 3 3 3 0 P-11 zinc finger DUF4164 PF13747.6 OWF53342.1 - 0.071 13.4 0.4 0.098 12.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Reo_P9 PF06043.11 OWF53342.1 - 0.092 12.1 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Reovirus P9-like family bZIP_1 PF00170.21 OWF53342.1 - 0.092 12.9 0.5 0.14 12.3 0.5 1.2 1 0 0 1 1 1 0 bZIP transcription factor RhoGEF67_u2 PF16614.5 OWF53343.1 - 0.0017 18.4 0.0 70 3.5 0.0 5.6 4 1 1 6 6 6 1 Unstructured region two on RhoGEF 6 and 7 DDE_Tnp_IS1595 PF12762.7 OWF53343.1 - 0.083 12.9 1.1 51 3.9 0.0 4.9 5 2 4 9 9 9 0 ISXO2-like transposase domain EF-hand_6 PF13405.6 OWF53344.1 - 6.4e-07 28.8 7.3 0.00029 20.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OWF53344.1 - 2.6e-06 27.8 1.8 2.6e-06 27.8 1.8 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF53344.1 - 0.026 14.4 0.1 0.026 14.4 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 OWF53344.1 - 0.13 11.8 0.1 0.13 11.8 0.1 4.4 5 1 0 5 5 5 0 EF hand Tctex-1 PF03645.13 OWF53345.1 - 2.8e-24 85.3 0.2 3.3e-24 85.1 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family RhoGEF PF00621.20 OWF53346.1 - 4.8e-38 131.2 2.6 4.8e-38 131.2 2.6 3.2 3 0 0 3 3 3 1 RhoGEF domain SH3_1 PF00018.28 OWF53346.1 - 5e-11 42.0 0.4 4.1e-10 39.1 0.0 2.6 3 0 0 3 3 3 1 SH3 domain CRAL_TRIO_2 PF13716.6 OWF53346.1 - 9.8e-11 42.0 0.0 4.6e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain SH3_9 PF14604.6 OWF53346.1 - 2.2e-06 27.4 0.2 1.5e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain CRAL_TRIO PF00650.20 OWF53346.1 - 3.2e-06 27.0 0.0 9.5e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO domain Spectrin PF00435.21 OWF53346.1 - 4e-06 27.3 12.4 0.0011 19.4 2.6 4.2 3 0 0 3 3 3 2 Spectrin repeat SH3_2 PF07653.17 OWF53346.1 - 6e-06 25.8 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 OWF53346.1 - 1.2e-05 25.8 0.3 4.5e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 PH domain PH_10 PF15411.6 OWF53346.1 - 0.0016 18.7 0.6 0.0043 17.3 0.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Fib_alpha PF08702.10 OWF53346.1 - 1 9.6 9.3 3.7 7.7 0.2 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family PLU-1 PF08429.11 OWF53346.1 - 7.4 5.6 15.0 0.94 8.6 5.6 2.7 2 1 1 3 3 3 0 PLU-1-like protein Med3 PF11593.8 OWF53348.1 - 0.01 15.0 3.1 0.01 15.0 3.1 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Bestrophin PF01062.21 OWF53348.1 - 1.3 8.3 9.1 0.091 12.1 2.9 1.9 1 1 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Peptidase_C65 PF10275.9 OWF53351.1 - 1.1e-81 274.0 0.4 1.3e-81 273.7 0.4 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 OWF53351.1 - 6.6e-05 23.4 0.0 0.0048 17.4 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease Guanylate_cyc PF00211.20 OWF53352.1 - 1.3e-24 86.8 1.5 5.5e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 OWF53352.1 - 0.002 18.5 0.0 0.014 15.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF1934 PF09148.10 OWF53352.1 - 0.0054 16.8 0.2 3.1 7.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1934) MA3 PF02847.17 OWF53352.1 - 0.01 15.8 1.2 2.5 8.1 0.0 3.9 3 0 0 3 3 3 0 MA3 domain TrwB_AAD_bind PF10412.9 OWF53352.1 - 0.021 13.8 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 OWF53352.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.19 OWF53353.1 - 2e-09 37.6 1.2 4.7e-09 36.4 0.9 1.6 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Spectrin PF00435.21 OWF53354.1 - 0 1052.7 941.6 5.6e-10 39.7 2.3 93.4 87 6 7 94 94 94 76 Spectrin repeat CH PF00307.31 OWF53354.1 - 5.6e-45 152.0 1.6 1.2e-20 73.7 0.3 5.4 3 0 0 3 3 3 2 Calponin homology (CH) domain KASH PF10541.9 OWF53354.1 - 8.5e-22 77.2 0.5 2e-21 76.0 0.5 1.7 1 0 0 1 1 1 1 Nuclear envelope localisation domain CAMSAP_CH PF11971.8 OWF53354.1 - 9.7e-08 31.7 0.0 0.0051 16.6 0.0 3.5 2 0 0 2 2 2 2 CAMSAP CH domain TPR_MLP1_2 PF07926.12 OWF53354.1 - 0.00089 19.3 2.6 0.00089 19.3 2.6 63.5 48 20 20 75 75 75 4 TPR/MLP1/MLP2-like protein DUF4806 PF16064.5 OWF53354.1 - 0.15 12.4 1.1 6.1 7.2 0.2 4.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) TIR-like PF10137.9 OWF53354.1 - 0.99 9.4 8.7 0.2 11.7 0.1 4.4 3 1 2 5 5 5 0 Predicted nucleotide-binding protein containing TIR-like domain NPBW PF15180.6 OWF53354.1 - 1.3 8.9 7.8 1.5 8.7 0.3 5.1 4 0 0 4 4 4 0 Neuropeptides B and W Ribonuclease_3 PF00636.26 OWF53355.1 - 2.5e-62 208.0 0.0 1.5e-36 125.2 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.22 OWF53355.1 - 1.2e-37 128.8 1.1 3.5e-37 127.3 1.1 1.8 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.14 OWF53355.1 - 3.1e-25 88.1 0.0 1.4e-24 86.1 0.0 2.3 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 OWF53355.1 - 2e-23 83.0 0.0 2.3e-15 56.9 0.0 4.4 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 OWF53355.1 - 2.2e-16 60.2 0.0 7.8e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_L27 PF01016.19 OWF53355.1 - 2.2e-05 24.4 0.2 13 5.9 0.1 5.9 1 1 6 7 7 7 1 Ribosomal L27 protein dsrm PF00035.26 OWF53355.1 - 0.00058 20.5 0.1 0.031 15.0 0.0 2.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif DEAD PF00270.29 OWF53355.1 - 0.0032 17.3 0.3 0.009 15.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase 2OG-FeII_Oxy_2 PF13532.6 OWF53356.1 - 1.5e-10 41.6 0.0 2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fibrinogen_C PF00147.18 OWF53357.1 - 3.2e-67 226.6 11.6 3.2e-67 226.6 11.6 2.0 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain HSBP1 PF06825.12 OWF53357.1 - 0.63 9.9 7.5 0.053 13.4 0.7 2.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Sds3 PF08598.11 OWF53358.1 - 1.2e-17 64.7 12.9 1.5e-16 61.1 14.4 1.8 1 1 1 2 2 2 2 Sds3-like Acetyltransf_1 PF00583.25 OWF53360.1 - 8.8e-17 61.4 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF53360.1 - 6.9e-11 42.4 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF53360.1 - 1.9e-10 40.7 0.0 3.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF53360.1 - 3e-07 30.3 0.0 5.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 OWF53360.1 - 2.3e-06 27.3 0.0 4.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OWF53360.1 - 0.0013 19.4 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OWF53360.1 - 0.0019 18.3 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RHD_DNA_bind PF00554.22 OWF53362.1 - 1.3e-69 233.4 0.2 3e-69 232.3 0.2 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 OWF53362.1 - 2.4e-38 130.3 0.1 5.2e-38 129.2 0.1 1.6 1 0 0 1 1 1 1 Rel homology dimerisation domain WYL_2 PF10902.8 OWF53363.1 - 2.6 8.5 4.7 16 5.9 0.6 2.5 1 1 1 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold SRI PF08236.11 OWF53363.1 - 3.9 7.7 14.2 0.16 12.1 0.3 3.3 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain Rap_GAP PF02145.15 OWF53364.1 - 1e-05 25.2 0.0 0.063 12.8 0.0 2.7 3 0 0 3 3 3 2 Rap/ran-GAP GASA PF02704.14 OWF53364.1 - 1.5 9.1 4.7 2.5 8.3 2.5 2.4 2 0 0 2 2 2 0 Gibberellin regulated protein PAP2 PF01569.21 OWF53365.1 - 1.2e-14 54.3 2.7 2.9e-14 53.0 2.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily PHO4 PF01384.20 OWF53365.1 - 0.2 10.7 3.3 0.48 9.4 3.3 1.7 1 1 0 1 1 1 0 Phosphate transporter family PAP2_3 PF14378.6 OWF53365.1 - 3 7.5 13.6 0.43 10.2 8.3 2.4 2 1 0 2 2 2 0 PAP2 superfamily UPF0016 PF01169.19 OWF53365.1 - 9.9 6.6 7.2 2.3 8.6 2.2 2.4 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 AAA PF00004.29 OWF53367.1 - 5.1e-43 146.7 0.0 9.9e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF53367.1 - 9.9e-10 38.1 0.9 1.8e-09 37.2 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OWF53367.1 - 2.4e-08 33.8 0.8 4.2e-08 33.0 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 OWF53367.1 - 7e-08 33.0 0.1 6.2e-05 23.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OWF53367.1 - 5.1e-07 29.8 0.2 6.1e-05 23.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OWF53367.1 - 9.3e-06 25.9 0.0 0.00018 21.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OWF53367.1 - 1.5e-05 24.8 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OWF53367.1 - 3e-05 24.3 0.4 0.0014 19.0 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.6 OWF53367.1 - 0.0033 17.6 0.0 0.011 15.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 OWF53367.1 - 0.0035 17.0 0.2 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_7 PF12775.7 OWF53367.1 - 0.0046 16.5 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 OWF53367.1 - 0.0048 16.1 0.0 0.0096 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OWF53367.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OWF53367.1 - 0.0054 17.3 0.1 0.022 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OWF53367.1 - 0.0089 15.9 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OWF53367.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 OWF53367.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OWF53367.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OWF53367.1 - 0.013 15.3 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OWF53367.1 - 0.016 15.6 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 OWF53367.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Thymidylate_kin PF02223.17 OWF53367.1 - 0.03 14.0 0.3 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 OWF53367.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OWF53367.1 - 0.051 13.3 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OWF53367.1 - 0.078 12.5 0.2 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OWF53367.1 - 0.08 12.6 0.0 0.26 11.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OWF53367.1 - 0.081 12.8 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 OWF53367.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OWF53367.1 - 0.11 11.8 0.1 0.66 9.3 0.0 2.2 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 OWF53367.1 - 0.12 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DASH_Dad2 PF08654.10 OWF53367.1 - 0.24 11.8 1.7 0.52 10.8 1.7 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 M PF02370.16 OWF53367.1 - 6.6 7.6 11.1 17 6.4 2.1 3.6 2 1 1 3 3 3 0 M protein repeat Myb_DNA-binding PF00249.31 OWF53368.1 - 1.1e-16 60.7 0.0 6e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain ELM2 PF01448.24 OWF53368.1 - 2.3e-09 37.8 0.0 2.3e-09 37.8 0.0 2.8 4 0 0 4 4 4 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 OWF53368.1 - 3.5e-07 30.0 4.7 0.0011 18.8 0.6 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OWF53368.1 - 9.6e-06 25.8 0.3 0.0032 17.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DRY_EERY PF09750.9 OWF53369.1 - 1.5e-40 138.6 0.0 1.5e-40 138.6 0.0 5.0 4 1 0 4 4 4 1 Alternative splicing regulator tRNA_bind_4 PF18490.1 OWF53370.1 - 0.15 11.8 0.0 54 3.5 0.0 3.2 1 1 3 4 4 4 0 tRNA-binding domain Njmu-R1 PF15053.6 OWF53370.1 - 0.25 10.4 1.6 16 4.4 0.1 3.3 1 1 3 4 4 4 0 Mjmu-R1-like protein family DUF1198 PF06711.11 OWF53370.1 - 0.41 10.7 4.2 31 4.6 0.1 4.1 1 1 5 6 6 6 0 Protein of unknown function (DUF1198) SNF PF00209.18 OWF53371.1 - 9.5e-192 638.3 33.5 1.1e-191 638.1 33.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AAA_17 PF13207.6 OWF53372.1 - 0.032 14.7 1.1 6.9 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Acyl_transf_3 PF01757.22 OWF53373.1 - 3.7e-25 88.7 36.6 5.9e-25 88.0 36.6 1.3 1 0 0 1 1 1 1 Acyltransferase family TB2_DP1_HVA22 PF03134.19 OWF53373.1 - 0.15 12.0 7.1 0.038 13.9 1.6 2.8 2 0 0 2 2 2 0 TB2/DP1, HVA22 family DUF2109 PF09882.9 OWF53373.1 - 7.8 6.6 9.3 0.24 11.5 0.3 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) Acyl_transf_3 PF01757.22 OWF53374.1 - 3.5e-06 26.3 8.5 4.4e-06 26.0 8.5 1.0 1 0 0 1 1 1 1 Acyltransferase family TB2_DP1_HVA22 PF03134.19 OWF53374.1 - 0.0015 18.4 1.7 0.0015 18.4 1.7 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF948 PF06103.11 OWF53376.1 - 0.013 15.7 0.9 0.015 15.6 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 OWF53376.1 - 0.045 13.9 1.9 0.049 13.8 1.9 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin-18_N PF10496.9 OWF53376.1 - 0.051 13.8 3.5 0.094 13.0 3.4 1.5 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Ribosomal_S15 PF00312.22 OWF53376.1 - 0.15 12.3 9.0 4.1 7.7 0.7 2.8 1 1 2 3 3 3 0 Ribosomal protein S15 SNCAIP_SNCA_bd PF16700.5 OWF53376.1 - 0.4 10.4 4.8 1.5 8.6 1.0 2.7 1 1 1 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain DUF724 PF05266.14 OWF53377.1 - 1.3e-05 25.2 7.8 1.5e-05 24.9 7.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF724) FlxA PF14282.6 OWF53377.1 - 4.2e-05 23.5 4.8 0.21 11.6 0.2 4.6 1 1 4 5 5 5 1 FlxA-like protein DUF948 PF06103.11 OWF53377.1 - 9.6e-05 22.6 10.1 0.61 10.4 10.0 3.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 OWF53377.1 - 0.0002 20.2 4.4 0.00024 19.9 4.4 1.1 1 0 0 1 1 1 1 AAA domain SlyX PF04102.12 OWF53377.1 - 0.0004 20.9 0.0 1.4 9.6 0.0 3.5 1 1 3 4 4 4 1 SlyX Fib_alpha PF08702.10 OWF53377.1 - 0.0032 17.7 14.9 0.018 15.2 6.1 2.3 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 OWF53377.1 - 0.0032 17.7 2.9 0.65 10.3 0.4 2.8 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 OWF53377.1 - 0.0032 17.8 5.4 0.018 15.4 5.4 2.2 1 1 0 1 1 1 1 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 OWF53377.1 - 0.0038 17.2 5.6 0.12 12.4 0.8 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding RBD PF02196.15 OWF53377.1 - 0.0042 17.1 7.5 2.3 8.4 0.7 3.9 1 1 1 2 2 2 1 Raf-like Ras-binding domain EzrA PF06160.12 OWF53377.1 - 0.0048 15.1 3.9 0.0048 15.1 3.9 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Bacillus_HBL PF05791.11 OWF53377.1 - 0.0061 16.4 2.1 0.019 14.8 2.2 1.8 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) MAD PF05557.13 OWF53377.1 - 0.0093 14.4 1.5 0.01 14.2 1.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4988 PF16378.5 OWF53377.1 - 0.013 15.2 5.7 3.3 7.4 2.4 3.2 1 1 1 2 2 2 0 Domain of unknown function DUF16 PF01519.16 OWF53377.1 - 0.014 15.9 2.6 0.63 10.6 2.6 2.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 Dynactin_p22 PF07426.11 OWF53377.1 - 0.014 15.2 11.0 0.013 15.3 6.1 2.1 1 1 1 2 2 2 0 Dynactin subunit p22 Sigma70_ner PF04546.13 OWF53377.1 - 0.018 14.9 2.5 0.85 9.5 0.2 2.3 1 1 1 2 2 2 0 Sigma-70, non-essential region Collagen_mid PF15984.5 OWF53377.1 - 0.024 14.4 0.9 0.05 13.3 0.6 1.6 1 1 1 2 2 2 0 Bacterial collagen, middle region Mod_r PF07200.13 OWF53377.1 - 0.03 14.4 3.0 0.16 12.1 3.0 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HAUS5 PF14817.6 OWF53377.1 - 0.033 13.0 3.0 0.054 12.3 3.0 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 Laminin_I PF06008.14 OWF53377.1 - 0.036 13.8 8.4 0.044 13.5 6.3 1.8 1 1 1 2 2 2 0 Laminin Domain I FAM76 PF16046.5 OWF53377.1 - 0.038 13.3 14.7 0.059 12.7 9.5 2.1 1 1 1 2 2 2 0 FAM76 protein Nsp1_C PF05064.13 OWF53377.1 - 0.053 13.3 0.1 0.15 11.9 0.1 1.8 1 1 0 1 1 1 0 Nsp1-like C-terminal region ATG16 PF08614.11 OWF53377.1 - 0.061 13.5 0.1 0.11 12.8 0.1 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FmiP_Thoc5 PF09766.9 OWF53377.1 - 0.088 12.1 7.7 0.14 11.4 6.6 1.8 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 CREPT PF16566.5 OWF53377.1 - 0.097 12.8 7.6 0.48 10.6 6.1 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour bZIP_1 PF00170.21 OWF53377.1 - 0.11 12.6 3.5 11 6.2 0.0 4.1 3 2 1 4 4 4 0 bZIP transcription factor KASH_CCD PF14662.6 OWF53377.1 - 0.12 12.2 5.0 0.12 12.2 3.1 1.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 OWF53377.1 - 0.12 11.5 4.0 0.37 10.0 1.9 2.0 1 1 2 3 3 3 0 HAP1 N-terminal conserved region DUF4200 PF13863.6 OWF53377.1 - 0.13 12.7 1.7 9.6 6.6 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.12 OWF53377.1 - 0.13 12.3 4.3 0.47 10.5 3.3 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF4472 PF14739.6 OWF53377.1 - 0.19 12.5 1.8 1.5 9.6 1.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) BST2 PF16716.5 OWF53377.1 - 0.24 12.0 1.7 2.6 8.7 0.3 2.5 1 1 2 3 3 2 0 Bone marrow stromal antigen 2 Filament PF00038.21 OWF53377.1 - 0.25 10.9 1.4 0.38 10.3 1.1 1.5 1 1 0 1 1 1 0 Intermediate filament protein ATP-synt_G PF04718.15 OWF53377.1 - 0.25 12.2 1.9 2.3 9.1 0.5 2.7 1 1 2 3 3 3 0 Mitochondrial ATP synthase g subunit KLRAQ PF10205.9 OWF53377.1 - 0.28 11.4 1.1 4.4 7.6 0.2 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.9 OWF53377.1 - 0.32 11.0 3.5 0.77 9.8 0.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 OWF53377.1 - 0.32 10.4 5.4 0.5 9.8 5.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal RPW8 PF05659.11 OWF53377.1 - 0.46 10.2 14.0 2.1 8.0 4.0 2.6 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Serine_rich PF08824.10 OWF53377.1 - 0.49 10.4 6.1 1.1 9.2 1.6 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain IFT57 PF10498.9 OWF53377.1 - 0.5 9.3 8.3 0.71 8.8 8.3 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Noelin-1 PF12308.8 OWF53377.1 - 0.52 10.3 11.9 0.24 11.4 2.8 2.6 1 1 2 3 3 3 0 Neurogenesis glycoprotein YabA PF06156.13 OWF53377.1 - 0.57 10.8 11.7 5.8e+02 1.2 11.7 3.5 1 1 0 1 1 1 0 Initiation control protein YabA Sec34 PF04136.15 OWF53377.1 - 0.58 10.0 10.7 0.7 9.8 5.1 2.1 1 1 1 2 2 2 0 Sec34-like family DUF1664 PF07889.12 OWF53377.1 - 0.65 10.0 14.0 2.1 8.4 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PI3K_P85_iSH2 PF16454.5 OWF53377.1 - 0.7 9.5 14.2 0.63 9.6 4.4 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain COG5 PF10392.9 OWF53377.1 - 1.2 9.3 23.6 1.3 9.2 9.9 2.8 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Med4 PF10018.9 OWF53377.1 - 1.4 8.6 14.1 1.4 8.6 5.2 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2935 PF11155.8 OWF53377.1 - 1.8 8.9 13.9 0.53 10.6 8.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Phage_int_SAM_6 PF18644.1 OWF53377.1 - 1.9 8.5 11.5 1.7 8.7 2.2 2.7 1 1 1 2 2 2 0 Phage integrase SAM-like domain BRE1 PF08647.11 OWF53377.1 - 2.1 8.5 6.0 3.9 7.6 2.6 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase MCPsignal PF00015.21 OWF53377.1 - 2.9 7.7 5.7 4.6 7.0 1.7 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DASH_Dam1 PF08653.10 OWF53377.1 - 5 7.0 10.9 44 4.0 0.2 4.1 3 1 0 4 4 4 0 DASH complex subunit Dam1 YvrJ PF12841.7 OWF53377.1 - 6.5 6.4 20.2 20 4.8 0.2 6.8 5 2 3 8 8 8 0 YvrJ protein family Toprim PF01751.22 OWF53377.1 - 8.6 6.7 14.1 37 4.6 1.4 2.8 1 1 1 2 2 2 0 Toprim domain Nup54 PF13874.6 OWF53377.1 - 9.1 6.4 8.0 16 5.6 7.8 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FlxA PF14282.6 OWF53378.1 - 0.0011 18.9 0.7 0.075 13.0 0.7 2.4 1 1 0 1 1 1 1 FlxA-like protein TMF_DNA_bd PF12329.8 OWF53378.1 - 0.003 17.5 0.4 0.014 15.4 0.3 1.7 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 OWF53378.1 - 0.0032 17.7 1.5 0.0051 17.0 1.5 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) COG5 PF10392.9 OWF53378.1 - 0.0045 17.2 5.5 0.0051 17.0 5.5 1.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 SlyX PF04102.12 OWF53378.1 - 0.0069 17.0 0.0 0.013 16.1 0.0 1.5 1 1 0 1 1 1 1 SlyX AAA_13 PF13166.6 OWF53378.1 - 0.0082 14.8 0.1 0.0083 14.8 0.1 1.0 1 0 0 1 1 1 1 AAA domain DUF4988 PF16378.5 OWF53378.1 - 0.0085 15.8 0.3 0.02 14.6 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function bZIP_1 PF00170.21 OWF53378.1 - 0.013 15.5 0.4 1.6 8.9 0.1 2.1 1 1 1 2 2 2 0 bZIP transcription factor Ribosomal_S15 PF00312.22 OWF53378.1 - 0.014 15.5 9.2 0.23 11.7 0.9 2.8 1 1 1 2 2 2 0 Ribosomal protein S15 PI3K_P85_iSH2 PF16454.5 OWF53378.1 - 0.018 14.7 1.1 0.02 14.5 1.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2680 PF10925.8 OWF53378.1 - 0.022 14.8 0.3 2.5 8.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2680) CENP-H PF05837.12 OWF53378.1 - 0.022 15.2 0.4 0.023 15.1 0.4 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 OWF53378.1 - 0.024 14.8 0.1 0.032 14.4 0.1 1.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 SNCAIP_SNCA_bd PF16700.5 OWF53378.1 - 0.028 14.2 1.2 0.028 14.2 1.2 2.1 1 1 1 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Baculo_PEP_C PF04513.12 OWF53378.1 - 0.028 14.4 0.9 0.031 14.3 0.9 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 OWF53378.1 - 0.035 13.9 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 Septum formation initiator RPW8 PF05659.11 OWF53378.1 - 0.038 13.7 1.1 0.13 11.9 1.1 1.7 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Syntaxin-18_N PF10496.9 OWF53378.1 - 0.058 13.6 4.9 0.36 11.1 4.9 2.2 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus YabA PF06156.13 OWF53378.1 - 0.068 13.8 0.9 0.15 12.7 0.9 1.6 1 1 0 1 1 1 0 Initiation control protein YabA FmiP_Thoc5 PF09766.9 OWF53378.1 - 0.075 12.3 1.1 0.074 12.3 1.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 MbeD_MobD PF04899.12 OWF53378.1 - 0.084 13.0 0.1 0.73 10.0 0.0 2.1 1 1 0 1 1 1 0 MbeD/MobD like Fib_alpha PF08702.10 OWF53378.1 - 0.084 13.1 1.5 0.13 12.4 1.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LPP PF04728.13 OWF53378.1 - 0.099 13.0 0.1 0.99 9.8 0.1 2.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper FAM76 PF16046.5 OWF53378.1 - 0.13 11.6 1.7 0.32 10.3 1.7 1.6 1 1 0 1 1 1 0 FAM76 protein YvrJ PF12841.7 OWF53378.1 - 0.19 11.3 6.1 5.1 6.7 0.2 3.5 3 1 1 4 4 4 0 YvrJ protein family Vac_Fusion PF02346.16 OWF53378.1 - 0.34 10.5 5.5 0.3 10.7 4.5 1.4 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 YliH PF10799.8 OWF53378.1 - 0.76 9.7 4.1 3 7.8 0.4 2.4 1 1 2 3 3 3 0 Biofilm formation protein (YliH/bssR) IATP PF04568.12 OWF53378.1 - 0.96 9.9 3.4 3.8 8.0 0.4 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF948 PF06103.11 OWF53379.1 - 7.7e-07 29.3 10.6 0.00095 19.4 2.8 2.5 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 OWF53379.1 - 3.6e-06 27.3 7.4 0.027 14.9 0.1 2.8 1 1 1 2 2 2 2 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 OWF53379.1 - 3.7e-06 26.8 3.1 0.39 10.7 0.1 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding FlxA PF14282.6 OWF53379.1 - 4.5e-06 26.6 4.5 0.55 10.2 0.7 4.5 1 1 1 2 2 2 2 FlxA-like protein AAA_13 PF13166.6 OWF53379.1 - 1.1e-05 24.4 1.3 3.4e-05 22.7 1.3 1.7 1 1 0 1 1 1 1 AAA domain Fib_alpha PF08702.10 OWF53379.1 - 4.2e-05 23.8 14.5 0.23 11.7 0.6 2.9 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family SlyX PF04102.12 OWF53379.1 - 6.3e-05 23.5 0.2 3.3 8.4 0.0 3.1 1 1 2 3 3 3 0 SlyX DUF16 PF01519.16 OWF53379.1 - 0.00012 22.6 1.0 0.31 11.5 0.4 2.9 1 1 1 2 2 2 2 Protein of unknown function DUF16 Cnn_1N PF07989.11 OWF53379.1 - 0.00021 21.4 0.6 2.1 8.6 0.1 3.5 1 1 2 3 3 3 1 Centrosomin N-terminal motif 1 ATG16 PF08614.11 OWF53379.1 - 0.00043 20.6 0.1 0.07 13.4 0.1 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 OWF53379.1 - 0.00045 20.3 0.7 2.4 8.3 0.0 3.4 2 2 1 3 3 3 0 bZIP transcription factor DUF4472 PF14739.6 OWF53379.1 - 0.0005 20.8 0.6 2 9.2 0.2 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4472) CENP-F_leu_zip PF10473.9 OWF53379.1 - 0.00053 20.0 3.8 0.11 12.5 0.5 2.2 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 OWF53379.1 - 0.00087 19.5 22.3 0.012 15.8 5.6 3.0 1 1 2 3 3 3 3 Golgi transport complex subunit 5 Spc24 PF08286.11 OWF53379.1 - 0.0011 19.2 1.7 1.4 9.2 1.7 2.9 1 1 0 1 1 1 1 Spc24 subunit of Ndc80 BLOC1_2 PF10046.9 OWF53379.1 - 0.0013 19.0 2.3 0.2 11.9 0.9 2.7 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sigma70_ner PF04546.13 OWF53379.1 - 0.0013 18.6 2.9 0.79 9.6 0.2 2.9 1 1 2 3 3 3 1 Sigma-70, non-essential region BRE1 PF08647.11 OWF53379.1 - 0.0014 18.7 5.4 0.055 13.5 1.8 2.1 1 1 1 2 2 2 1 BRE1 E3 ubiquitin ligase DUF4618 PF15397.6 OWF53379.1 - 0.0017 17.8 10.8 0.14 11.5 4.5 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.12 OWF53379.1 - 0.0017 18.4 6.1 0.22 11.5 6.1 2.1 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4988 PF16378.5 OWF53379.1 - 0.0025 17.5 3.1 0.62 9.7 0.3 2.6 1 1 2 3 3 3 1 Domain of unknown function GAS PF13851.6 OWF53379.1 - 0.0025 17.2 1.0 0.27 10.5 0.4 2.0 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 OWF53379.1 - 0.0031 17.6 2.5 0.13 12.4 0.3 2.1 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.15 OWF53379.1 - 0.0032 17.2 0.0 6 6.7 0.0 2.9 1 1 2 3 3 3 0 Septum formation initiator PI3K_P85_iSH2 PF16454.5 OWF53379.1 - 0.0045 16.6 12.3 0.18 11.4 4.6 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Snf7 PF03357.21 OWF53379.1 - 0.0052 16.4 0.9 0.8 9.3 0.3 2.5 1 1 2 3 3 3 1 Snf7 Prefoldin PF02996.17 OWF53379.1 - 0.0057 16.6 1.7 3.8 7.4 0.1 2.9 1 1 2 3 3 3 0 Prefoldin subunit YabA PF06156.13 OWF53379.1 - 0.0065 17.1 10.3 0.62 10.7 0.6 3.2 1 1 0 2 2 2 1 Initiation control protein YabA Bacillus_HBL PF05791.11 OWF53379.1 - 0.0068 16.2 3.4 0.36 10.6 0.5 2.2 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF4200 PF13863.6 OWF53379.1 - 0.0071 16.7 2.3 6 7.3 0.5 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) MIP-T3_C PF17749.1 OWF53379.1 - 0.008 16.2 4.1 12 5.9 0.1 3.2 1 1 2 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region MAD PF05557.13 OWF53379.1 - 0.0082 14.6 1.4 0.0098 14.3 1.4 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF724 PF05266.14 OWF53379.1 - 0.0087 15.9 6.8 0.016 15.0 6.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF724) Gene66 PF02053.15 OWF53379.1 - 0.0089 15.7 9.7 0.93 9.1 0.6 3.2 1 1 2 3 3 3 2 Gene 66 (IR5) protein Prefoldin_2 PF01920.20 OWF53379.1 - 0.0094 15.9 0.7 5.1 7.1 0.1 2.7 2 1 1 3 3 3 0 Prefoldin subunit Nsp1_C PF05064.13 OWF53379.1 - 0.011 15.6 0.1 0.1 12.4 0.1 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region Plk4_PB2 PF18409.1 OWF53379.1 - 0.012 16.3 11.4 2.2 9.0 0.8 3.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 KLRAQ PF10205.9 OWF53379.1 - 0.013 15.7 0.3 4 7.7 0.1 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Arteri_Gl PF00951.18 OWF53379.1 - 0.017 14.9 7.9 0.42 10.4 0.8 3.2 1 1 3 4 4 4 0 Arterivirus GL envelope glycoprotein KASH_CCD PF14662.6 OWF53379.1 - 0.019 14.8 7.4 0.21 11.4 2.6 2.0 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH FANCI_S4 PF14678.6 OWF53379.1 - 0.02 14.0 16.8 0.085 12.0 15.8 2.3 1 1 0 1 1 1 0 FANCI solenoid 4 EzrA PF06160.12 OWF53379.1 - 0.028 12.6 5.4 0.072 11.2 4.3 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Cob_adeno_trans PF01923.18 OWF53379.1 - 0.035 14.2 3.0 0.43 10.7 0.7 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Tektin PF03148.14 OWF53379.1 - 0.036 12.8 8.6 0.44 9.3 2.4 2.4 1 1 1 2 2 2 0 Tektin family DUF730 PF05325.11 OWF53379.1 - 0.043 13.8 1.3 21 5.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF730) DUF1664 PF07889.12 OWF53379.1 - 0.051 13.6 15.0 0.23 11.5 5.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BORCS6 PF10157.9 OWF53379.1 - 0.062 13.5 13.0 0.64 10.2 1.8 2.9 1 1 0 2 2 2 0 BLOC-1-related complex sub-unit 6 COG2 PF06148.11 OWF53379.1 - 0.062 13.4 1.9 2.9 8.0 0.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Taxilin PF09728.9 OWF53379.1 - 0.064 12.4 6.3 2 7.5 0.4 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein FmiP_Thoc5 PF09766.9 OWF53379.1 - 0.069 12.4 9.6 2.3 7.4 0.7 2.9 1 1 2 3 3 3 0 Fms-interacting protein/Thoc5 Dynactin_p22 PF07426.11 OWF53379.1 - 0.078 12.8 5.8 0.35 10.7 5.8 2.0 1 1 0 1 1 1 0 Dynactin subunit p22 Imm7 PF15585.6 OWF53379.1 - 0.086 13.1 6.3 3.9 7.8 0.3 3.1 1 1 1 2 2 2 0 Immunity protein 7 Laminin_II PF06009.12 OWF53379.1 - 0.091 12.8 3.2 1.1 9.3 0.3 2.1 1 1 1 2 2 2 0 Laminin Domain II IFT57 PF10498.9 OWF53379.1 - 0.12 11.4 13.9 0.16 10.9 13.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HAP1_N PF04849.13 OWF53379.1 - 0.13 11.4 3.0 2.7 7.1 0.5 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region CdvA PF18822.1 OWF53379.1 - 0.14 11.9 7.6 4.8 7.0 0.4 3.4 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Lebercilin PF15619.6 OWF53379.1 - 0.15 11.7 4.7 2.4 7.8 1.4 2.5 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_I PF06008.14 OWF53379.1 - 0.16 11.7 7.3 0.85 9.3 5.6 2.1 1 1 1 2 2 2 0 Laminin Domain I ATP-synt_G PF04718.15 OWF53379.1 - 0.17 12.7 1.4 6.7 7.6 1.4 2.6 1 1 0 1 1 1 0 Mitochondrial ATP synthase g subunit FAM76 PF16046.5 OWF53379.1 - 0.19 11.1 13.7 0.5 9.7 5.5 2.0 1 1 0 2 2 2 0 FAM76 protein DUF677 PF05055.12 OWF53379.1 - 0.2 10.5 6.7 0.78 8.6 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF677) RPW8 PF05659.11 OWF53379.1 - 0.25 11.0 14.2 2.3 7.9 2.5 3.1 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Filament PF00038.21 OWF53379.1 - 0.26 10.8 3.6 6.3 6.3 0.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein Med4 PF10018.9 OWF53379.1 - 0.34 10.6 9.5 1.3 8.7 3.3 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 BAR_3 PF16746.5 OWF53379.1 - 0.37 10.5 10.5 0.91 9.2 0.5 2.2 1 1 0 2 2 2 0 BAR domain of APPL family HMMR_N PF15905.5 OWF53379.1 - 0.49 9.8 8.0 0.64 9.4 8.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 OWF53379.1 - 0.52 10.6 6.5 2.2 8.6 6.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) zf-C4H2 PF10146.9 OWF53379.1 - 0.6 10.4 11.6 0.77 10.0 11.6 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Syntaxin-18_N PF10496.9 OWF53379.1 - 0.66 10.3 24.2 1.1 9.6 3.3 4.6 1 1 3 4 4 3 0 SNARE-complex protein Syntaxin-18 N-terminus Jnk-SapK_ap_N PF09744.9 OWF53379.1 - 0.95 9.7 5.0 6 7.1 1.2 2.1 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4665 PF15679.5 OWF53379.1 - 1 10.0 10.6 10 6.8 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) CREPT PF16566.5 OWF53379.1 - 1.2 9.3 5.8 14 5.8 5.7 2.2 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Noelin-1 PF12308.8 OWF53379.1 - 1.3 9.0 11.8 2.6 8.1 2.3 2.9 1 1 2 3 3 3 0 Neurogenesis glycoprotein NACHT_N PF17100.5 OWF53379.1 - 1.5 8.6 5.1 11 5.8 0.2 2.7 1 1 1 3 3 3 0 N-terminal domain of NWD NACHT-NTPase Syntaxin_2 PF14523.6 OWF53379.1 - 1.6 9.1 16.3 7.7e+03 -2.7 16.3 2.9 1 1 0 1 1 0 0 Syntaxin-like protein DUF4795 PF16043.5 OWF53379.1 - 1.9 8.0 9.6 6.2 6.4 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) FAP206 PF12018.8 OWF53379.1 - 3.9 6.9 7.8 3.8 6.9 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF2935 PF11155.8 OWF53379.1 - 3.9 7.8 17.9 54 4.1 7.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Ribosomal_S15 PF00312.22 OWF53379.1 - 5 7.4 37.9 7.9 6.8 1.2 6.8 1 1 4 5 5 4 0 Ribosomal protein S15 MCPsignal PF00015.21 OWF53379.1 - 5.2 6.9 6.0 11 5.8 2.5 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RE_Bpu10I PF09549.10 OWF53380.1 - 0.13 11.8 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Bpu10I restriction endonuclease YhhN PF07947.14 OWF53381.1 - 1.1e-32 113.2 17.2 1.5e-32 112.7 17.2 1.2 1 0 0 1 1 1 1 YhhN family Arf PF00025.21 OWF53382.1 - 3.5e-32 111.2 0.0 4.6e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OWF53382.1 - 3.2e-11 43.0 0.0 4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OWF53382.1 - 1.1e-08 34.8 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF53382.1 - 2.2e-08 34.3 0.0 3.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OWF53382.1 - 0.00016 21.8 0.1 0.00057 20.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 OWF53382.1 - 0.0005 19.3 0.1 0.0097 15.1 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 OWF53382.1 - 0.00064 19.1 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Zeta_toxin PF06414.12 OWF53382.1 - 0.0039 16.5 0.0 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 OWF53382.1 - 0.012 15.3 0.1 0.024 14.3 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OWF53382.1 - 0.02 15.1 0.1 0.064 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OWF53382.1 - 0.036 14.3 0.0 0.063 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF53382.1 - 0.045 14.3 0.0 0.074 13.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OWF53382.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OWF53382.1 - 0.14 11.7 0.5 7 6.2 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cyclin_N PF00134.23 OWF53383.1 - 4.2e-13 49.2 0.0 7.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF53383.1 - 0.0095 16.0 0.0 0.036 14.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Rubis-subs-bind PF09273.11 OWF53384.1 - 5.4e-23 82.1 0.3 9.7e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OWF53384.1 - 4e-14 53.4 0.0 4.7e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 SET domain HypA PF01155.19 OWF53384.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 OWF53384.1 - 0.17 12.0 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zw10 PF06248.13 OWF53385.1 - 2.2e-128 429.2 18.2 2.6e-128 429.0 18.2 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 NPV_P10 PF05531.12 OWF53385.1 - 0.021 15.3 11.2 3 8.4 2.2 4.0 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DNA_repr_REX1B PF14966.6 OWF53385.1 - 0.049 14.3 2.5 0.83 10.4 0.6 3.4 3 0 0 3 3 3 0 DNA repair REX1-B DUF948 PF06103.11 OWF53385.1 - 0.4 11.0 2.9 3.3 8.0 2.9 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 OWF53385.1 - 0.68 10.6 6.7 1 10.0 4.5 2.4 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HR1 PF02185.16 OWF53385.1 - 6.9 6.9 6.6 82 3.4 1.5 3.7 3 0 0 3 3 3 0 Hr1 repeat Ank_2 PF12796.7 OWF53386.1 - 6.7e-21 74.7 1.1 2.6e-08 34.3 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53386.1 - 6.9e-14 52.0 0.3 0.00038 21.0 0.1 4.3 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF53386.1 - 1.1e-12 47.9 0.3 5.6e-06 26.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF53386.1 - 6.7e-05 23.2 0.1 1.1 9.8 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 OWF53386.1 - 0.00029 21.1 0.0 4.3 8.2 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat TIR_2 PF13676.6 OWF53387.1 - 5.5e-31 107.6 0.0 9.4e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 OWF53387.1 - 2.7e-24 85.9 0.0 5.9e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 OWF53387.1 - 0.11 12.8 0.2 1.3 9.4 0.0 2.4 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) DUF1382 PF07131.11 OWF53387.1 - 0.12 12.4 0.6 3.3 7.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) CiPC PF15800.5 OWF53388.1 - 1.1e-14 55.0 0.5 1.1e-14 55.0 0.5 3.3 2 1 1 3 3 3 1 Clock interacting protein circadian GCN5L1 PF06320.13 OWF53388.1 - 4.6 7.4 9.3 0.14 12.4 0.8 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FSIP1 PF15554.6 OWF53389.1 - 4.8e-67 226.8 18.8 4.8e-67 226.8 18.8 2.2 2 1 0 2 2 2 1 FSIP1 family SH3_2 PF07653.17 OWF53390.1 - 4.8e-11 42.2 0.0 9.9e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF53390.1 - 0.00093 18.8 0.1 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OWF53390.1 - 0.0048 16.7 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF5521 PF17659.1 OWF53391.1 - 7.2e-68 229.3 3.8 7.2e-68 229.3 3.8 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5521) tRNA_anti-codon PF01336.25 OWF53391.1 - 0.00018 21.4 0.1 0.024 14.6 0.0 2.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 OWF53391.1 - 0.00053 19.8 0.5 0.023 14.4 0.0 3.2 3 1 1 4 4 4 1 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 OWF53391.1 - 0.0045 17.0 0.0 0.11 12.5 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4539) Macoilin PF09726.9 OWF53391.1 - 0.28 9.7 14.3 0.42 9.1 14.3 1.2 1 0 0 1 1 1 0 Macoilin family Homeodomain PF00046.29 OWF53392.1 - 4.4e-14 52.1 4.5 8.3e-14 51.2 4.5 1.5 1 0 0 1 1 1 1 Homeodomain RhoGAP PF00620.27 OWF53393.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain DUF4570 PF15134.6 OWF53393.1 - 0.38 10.8 13.2 0.02 14.9 6.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) DUF5526 PF17664.1 OWF53393.1 - 0.96 9.0 8.6 2.6 7.6 8.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5526) Rrp15p PF07890.12 OWF53394.1 - 3.5e-25 88.9 10.2 5.8e-25 88.2 10.2 1.4 1 0 0 1 1 1 1 Rrp15p PRTP PF01366.18 OWF53394.1 - 0.12 10.4 2.0 0.17 9.9 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein CpXC PF14353.6 OWF53395.1 - 0.042 13.9 0.3 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 CpXC protein TolA PF06519.11 OWF53396.1 - 0.12 12.6 0.0 27 5.0 0.0 2.6 2 0 0 2 2 2 0 TolA C-terminal TFIID-31kDa PF02291.15 OWF53396.1 - 0.13 12.3 0.2 12 6.0 0.0 2.7 3 0 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit fn3 PF00041.21 OWF53397.1 - 3.4e-199 645.8 94.9 2e-11 44.1 0.3 36.1 35 0 0 35 35 35 29 Fibronectin type III domain Laminin_EGF PF00053.24 OWF53397.1 - 4.1e-68 225.3 192.1 3e-10 40.1 12.8 10.8 10 0 0 10 10 10 10 Laminin EGF domain Laminin_G_2 PF02210.24 OWF53397.1 - 1.1e-30 106.9 0.1 7.1e-14 52.5 0.0 4.4 4 0 0 4 4 4 2 Laminin G domain Laminin_N PF00055.17 OWF53397.1 - 1.6e-25 90.1 0.2 1.6e-25 90.1 0.2 4.7 6 0 0 6 6 2 2 Laminin N-terminal (Domain VI) Pur_ac_phosph_N PF16656.5 OWF53397.1 - 1.1e-24 86.9 95.0 0.02 15.4 0.3 26.2 26 4 0 27 27 25 7 Purple acid Phosphatase, N-terminal domain Laminin_G_1 PF00054.23 OWF53397.1 - 3.7e-24 85.4 0.0 3e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 OWF53397.1 - 8e-16 58.5 0.9 1.4e-12 48.0 0.1 3.9 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily ChitinaseA_N PF08329.10 OWF53397.1 - 5.3e-15 55.2 25.3 1.2 8.8 0.0 17.7 18 2 1 19 19 19 2 Chitinase A, N-terminal domain fn3_2 PF16893.5 OWF53397.1 - 9.1e-07 29.0 7.4 58 3.9 0.0 11.6 13 0 0 13 13 13 0 Fibronectin type III domain fn3_4 PF16794.5 OWF53397.1 - 0.0022 17.9 0.0 0.55 10.2 0.0 4.5 4 0 0 4 4 4 1 Fibronectin-III type domain SusE PF14292.6 OWF53397.1 - 0.0081 16.4 18.0 31 4.8 0.0 10.5 13 1 1 14 14 12 0 SusE outer membrane protein PhoD_N PF16655.5 OWF53397.1 - 0.0086 16.6 7.3 4.2 8.0 0.0 7.9 10 0 0 10 10 7 1 PhoD-like phosphatase, N-terminal domain PTP_tm PF18861.1 OWF53397.1 - 0.094 12.7 7.3 1.2e+02 2.6 0.0 7.6 9 0 0 9 9 9 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EGF PF00008.27 OWF53399.1 - 4.9e-27 93.9 130.3 1.5e-06 28.4 5.0 10.1 8 1 0 8 8 8 7 EGF-like domain hEGF PF12661.7 OWF53399.1 - 2.3e-11 43.9 101.4 0.0025 18.4 3.9 10.2 8 0 0 8 8 8 6 Human growth factor-like EGF EGF_2 PF07974.13 OWF53399.1 - 2.6e-09 37.3 142.3 0.0033 17.8 12.9 9.1 8 0 0 8 8 8 7 EGF-like domain zf-B_box PF00643.24 OWF53400.1 - 0.0017 18.5 11.7 0.003 17.7 11.7 1.4 1 0 0 1 1 1 1 B-box zinc finger Herpes_UL92 PF03048.14 OWF53400.1 - 0.3 10.8 13.3 1.6 8.4 12.4 2.3 1 1 0 1 1 1 0 UL92 family LMBR1 PF04791.16 OWF53400.1 - 0.35 9.7 0.9 0.42 9.5 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 OWF53400.1 - 0.39 9.3 7.6 0.51 8.9 7.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A EGF_2 PF07974.13 OWF53401.1 - 1.7e-16 60.2 141.8 5.6e-05 23.4 8.7 10.8 9 0 0 9 9 9 8 EGF-like domain EGF PF00008.27 OWF53401.1 - 2.7e-16 59.5 146.6 4.3e-05 23.7 5.6 12.3 13 0 0 13 13 13 8 EGF-like domain hEGF PF12661.7 OWF53401.1 - 2.4e-12 47.0 124.2 0.00079 20.0 6.9 12.8 12 0 0 12 12 12 8 Human growth factor-like EGF EGF_CA PF07645.15 OWF53401.1 - 0.0017 18.6 4.3 0.0017 18.6 4.3 11.6 8 2 2 10 10 10 2 Calcium-binding EGF domain adh_short PF00106.25 OWF53402.1 - 1.6e-43 148.5 0.0 2.2e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF53402.1 - 7.6e-32 110.7 0.0 1.1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF53402.1 - 1.9e-09 37.7 0.0 2.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF53402.1 - 4e-06 26.4 0.0 7.3e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OWF53402.1 - 2e-05 24.2 0.1 8.4e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF53402.1 - 0.013 14.9 0.1 0.029 13.8 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OWF53402.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 OWF53402.1 - 0.048 12.7 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 OWF53402.1 - 0.096 12.2 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 OWF53402.1 - 0.18 10.8 0.6 0.87 8.5 0.6 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dak1 PF02733.17 OWF53403.1 - 7.3e-86 287.9 0.1 1.2e-85 287.2 0.1 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OWF53403.1 - 3.1e-45 154.2 4.7 3.4e-45 154.1 0.8 2.1 2 0 0 2 2 2 1 DAK2 domain DUF4213 PF13938.6 OWF53403.1 - 0.013 15.7 1.2 0.29 11.4 0.2 3.1 3 0 0 3 3 3 0 Putative heavy-metal chelation Homeodomain PF00046.29 OWF53405.1 - 1.1e-21 76.4 1.7 2.3e-21 75.4 1.7 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 OWF53405.1 - 1.2e-05 25.0 1.9 2.2e-05 24.1 1.9 1.5 1 0 0 1 1 1 1 OAR domain Alpha-2-MRAP_N PF06400.11 OWF53405.1 - 0.024 14.6 1.8 0.024 14.6 1.8 1.9 3 0 0 3 3 3 0 Alpha-2-macroglobulin RAP, N-terminal domain PI3K_1B_p101 PF10486.9 OWF53405.1 - 1.6 6.5 6.7 2.1 6.0 6.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Homeodomain PF00046.29 OWF53406.1 - 3.8e-23 81.1 2.8 3.8e-23 81.1 2.8 1.8 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 OWF53406.1 - 1.7e-05 24.4 3.3 3.7e-05 23.4 3.3 1.6 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF53406.1 - 0.012 15.5 0.1 0.044 13.7 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain TCP PF03634.13 OWF53406.1 - 0.11 13.0 8.1 0.21 12.2 3.0 2.3 2 0 0 2 2 2 0 TCP family transcription factor TPR_12 PF13424.6 OWF53407.1 - 1.9e-05 24.9 0.7 0.0013 19.0 0.1 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Consortin_C PF15281.6 OWF53407.1 - 0.00016 21.6 0.0 0.00064 19.7 0.0 2.0 1 0 0 1 1 1 1 Consortin C-terminus TPR_2 PF07719.17 OWF53407.1 - 0.00048 20.0 4.4 2.6 8.4 0.8 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF53407.1 - 0.013 15.6 5.2 3.5 8.1 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OWF53407.1 - 0.016 15.1 3.4 0.017 15.0 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF53407.1 - 0.021 14.6 7.9 3.4 7.7 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Orf78 PF06024.12 OWF53407.1 - 0.27 11.6 0.0 0.27 11.6 0.0 3.0 2 1 0 2 2 2 0 Orf78 (ac78) Zip PF02535.22 OWF53407.1 - 5.8 6.0 8.5 15 4.6 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter PLDc_3 PF13918.6 OWF53408.1 - 1.6e-34 119.1 0.1 2.4e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 OWF53408.1 - 4.7e-24 84.8 0.1 4.1e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OWF53408.1 - 2.1e-13 49.8 4.2 1.8e-07 31.0 0.4 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif EF-hand_1 PF00036.32 OWF53410.1 - 4.1e-34 113.6 19.3 2.2e-09 36.2 1.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF53410.1 - 3.4e-29 98.3 9.4 2e-08 33.5 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OWF53410.1 - 8.4e-28 96.6 10.5 1.1e-15 57.8 4.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF53410.1 - 1.2e-24 84.6 11.7 4.4e-07 29.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF53410.1 - 3e-23 81.4 13.8 3.4e-14 52.4 1.0 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 OWF53410.1 - 2.6e-14 53.3 0.4 1.6e-07 31.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF53410.1 - 6.5e-10 38.9 3.5 0.00022 21.1 0.8 2.3 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF53410.1 - 1.5e-09 38.2 0.5 0.00015 22.0 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF53410.1 - 5.6e-05 23.2 4.3 0.029 14.6 0.1 3.3 1 1 2 3 3 3 3 Dockerin type I domain Caleosin PF05042.13 OWF53410.1 - 0.00019 21.4 0.3 1.7 8.6 0.0 3.2 2 2 1 3 3 3 2 Caleosin related protein EF-hand_14 PF17959.1 OWF53410.1 - 0.0002 21.6 0.4 0.026 14.9 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 OWF53410.1 - 0.00034 21.4 0.2 0.0026 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 OWF53410.1 - 0.00079 19.4 0.0 0.48 10.5 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 OWF53410.1 - 0.0082 16.1 3.1 2.5 8.1 0.2 2.6 1 1 1 3 3 3 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 OWF53410.1 - 0.01 16.2 2.0 0.013 15.8 0.3 2.0 3 0 0 3 3 3 0 RNA polymerase Rpb4 DUF5580 PF17743.1 OWF53410.1 - 0.013 14.1 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF2666 PF10869.8 OWF53410.1 - 0.03 14.5 2.5 1.7 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF1151 PF06625.11 OWF53410.1 - 0.055 13.4 0.2 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) EF-hand_10 PF14788.6 OWF53410.1 - 0.12 12.3 3.8 4.2 7.3 0.8 2.6 2 1 0 2 2 2 0 EF hand DUF3349 PF11829.8 OWF53410.1 - 0.17 12.7 1.1 14 6.5 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) DUF1007 PF06226.13 OWF53410.1 - 0.19 11.7 0.8 19 5.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1007) FGAR-AT_linker PF18072.1 OWF53410.1 - 0.19 12.3 0.4 30 5.2 0.0 2.9 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_1 PF00036.32 OWF53411.1 - 1e-39 131.1 7.4 2.7e-09 35.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF53411.1 - 1.6e-34 118.1 1.3 6.1e-17 61.8 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF53411.1 - 1.2e-30 102.8 2.0 3.1e-08 32.9 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF53411.1 - 4.8e-28 96.8 10.8 1.8e-13 50.1 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF53411.1 - 9.3e-28 94.5 6.4 5.2e-07 28.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF53411.1 - 5.4e-14 52.3 0.1 8.7e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF53411.1 - 5.6e-08 32.7 0.2 0.0096 15.9 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF53411.1 - 2e-07 31.3 0.1 0.0083 16.4 0.0 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF53411.1 - 2.8e-05 24.9 0.0 0.013 16.4 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 OWF53411.1 - 0.00018 21.5 0.2 0.083 12.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 OWF53411.1 - 0.00039 20.4 0.0 1.1 9.2 0.0 3.5 2 2 2 4 4 4 2 Caleosin related protein Dockerin_1 PF00404.18 OWF53411.1 - 0.024 14.8 1.9 11 6.2 0.0 3.4 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_14 PF17959.1 OWF53411.1 - 0.035 14.4 0.2 5.3 7.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain RNA_pol_Rpb4 PF03874.16 OWF53411.1 - 0.053 13.8 1.4 7.2 7.0 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 DUF2267 PF10025.9 OWF53411.1 - 0.054 13.8 0.0 0.19 12.0 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Tetraspanin PF00335.20 OWF53413.1 - 3.2e-34 118.6 14.9 3.9e-34 118.4 14.9 1.1 1 0 0 1 1 1 1 Tetraspanin family Flp1_like PF16982.5 OWF53413.1 - 0.0065 15.9 1.7 0.0065 15.9 1.7 3.2 3 1 0 3 3 3 1 Putative Flagellin, Flp1-like, domain Spectrin PF00435.21 OWF53414.1 - 0 1650.3 313.8 3.8e-24 85.2 2.4 31.4 31 0 0 31 31 31 31 Spectrin repeat CH PF00307.31 OWF53414.1 - 6.1e-48 161.5 0.3 2.3e-24 85.6 0.0 4.5 4 0 0 4 4 4 2 Calponin homology (CH) domain PH_9 PF15410.6 OWF53414.1 - 5.9e-17 62.1 0.0 3.5e-16 59.6 0.0 2.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OWF53414.1 - 1.8e-09 38.1 1.4 9e-09 35.8 0.0 3.1 3 0 0 3 3 3 1 PH domain SH3_9 PF14604.6 OWF53414.1 - 1.4e-06 28.0 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF53414.1 - 2.2e-06 27.2 0.1 5.5e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 OWF53414.1 - 0.00023 21.4 0.0 0.0007 19.8 0.0 1.9 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 OWF53414.1 - 0.0032 17.5 0.0 0.014 15.5 0.0 2.1 1 0 0 1 1 1 1 SH3 domain CAMSAP_CH PF11971.8 OWF53414.1 - 0.0078 16.0 0.0 0.41 10.5 0.0 3.1 2 0 0 2 2 2 1 CAMSAP CH domain SH3_2 PF07653.17 OWF53414.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain FAD_binding_3 PF01494.19 OWF53415.1 - 6.9e-27 94.6 0.0 8.4e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OWF53415.1 - 4.7e-06 26.7 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OWF53415.1 - 9e-06 24.9 0.0 8e-05 21.8 0.0 2.2 2 1 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 OWF53415.1 - 0.00098 18.8 0.1 0.002 17.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OWF53415.1 - 0.0014 19.2 1.2 0.0025 18.3 0.5 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OWF53415.1 - 0.0032 17.4 0.1 0.0054 16.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 OWF53415.1 - 0.0048 16.2 0.3 0.016 14.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF53415.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 OWF53415.1 - 0.021 13.5 0.2 0.063 12.0 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 OWF53415.1 - 0.082 13.4 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OWF53415.1 - 0.14 11.2 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 OWF53415.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 OWF53415.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain OATP PF03137.20 OWF53416.1 - 2.8e-137 458.3 21.8 8.2e-137 456.8 21.8 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF53416.1 - 9.1e-16 57.7 43.8 1.5e-15 57.0 17.7 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily ATG22 PF11700.8 OWF53416.1 - 9.6e-05 21.2 2.1 0.00019 20.2 2.1 1.5 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Kazal_2 PF07648.15 OWF53416.1 - 0.00079 19.5 11.4 0.0018 18.4 11.4 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF53416.1 - 0.034 14.1 5.1 0.11 12.6 5.1 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain C1q PF00386.21 OWF53417.1 - 2.4e-20 73.0 0.6 3.1e-20 72.7 0.6 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF53417.1 - 0.00066 19.6 1.3 0.001 19.0 1.3 1.4 1 0 0 1 1 1 1 BclA C-terminal domain A_deaminase_N PF08451.11 OWF53417.1 - 0.0051 17.1 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal ELL PF10390.9 OWF53417.1 - 0.12 11.9 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Pkinase_Tyr PF07714.17 OWF53418.1 - 7.3e-180 595.7 4.7 4.5e-71 239.2 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OWF53418.1 - 1.6e-107 358.8 0.4 2.5e-44 151.6 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain RIO1 PF01163.22 OWF53418.1 - 1.4e-08 34.6 3.1 0.00099 18.7 0.5 2.8 3 0 0 3 3 3 2 RIO1 family FERM_F2 PF18377.1 OWF53418.1 - 3e-07 30.4 0.4 7.2e-07 29.2 0.4 1.6 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain Pkinase_fungal PF17667.1 OWF53418.1 - 0.0017 17.2 2.6 0.46 9.2 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase ABC1 PF03109.16 OWF53418.1 - 0.0022 18.2 0.1 0.6 10.3 0.0 3.4 3 0 0 3 3 3 1 ABC1 family PIP49_C PF12260.8 OWF53418.1 - 0.011 15.4 0.1 0.031 13.9 0.1 1.8 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kinase-like PF14531.6 OWF53418.1 - 0.011 15.1 0.0 2.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OWF53418.1 - 0.064 12.2 0.7 20 4.0 0.0 3.6 3 1 0 3 3 3 0 Haspin like kinase domain Jak1_Phl PF17887.1 OWF53418.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Kdo PF06293.14 OWF53418.1 - 0.24 10.7 3.0 10 5.4 0.2 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 OWF53419.1 - 1.4e-24 86.1 0.3 3.1e-07 30.8 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF53419.1 - 5.7e-23 81.3 0.3 6.6e-12 45.9 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF53419.1 - 6.2e-20 71.0 0.2 2.6e-08 34.0 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF53419.1 - 3.6e-17 60.7 0.0 0.0013 19.1 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OWF53419.1 - 9.6e-17 60.6 0.0 0.00025 21.4 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat MCR_D PF02505.14 OWF53419.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D DUF4250 PF14056.6 OWF53419.1 - 0.13 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) HMGL-like PF00682.19 OWF53420.1 - 6e-10 39.1 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like YHYH PF14240.6 OWF53420.1 - 0.00025 21.0 0.2 0.00042 20.3 0.2 1.4 1 0 0 1 1 1 1 YHYH protein 5-FTHF_cyc-lig PF01812.20 OWF53421.1 - 5e-34 117.8 0.0 7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 OWF53421.1 - 4.4e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bee_toxin PF17454.2 OWF53421.1 - 0.029 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Honey bee toxin SWIB PF02201.18 OWF53421.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain Ax_dynein_light PF10211.9 OWF53422.1 - 6.5e-94 313.1 12.3 8.7e-94 312.7 12.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain RIB43A PF05914.12 OWF53422.1 - 7.6e-05 21.6 9.0 7.6e-05 21.6 9.0 1.5 2 0 0 2 2 2 1 RIB43A Mei5 PF10376.9 OWF53422.1 - 0.0019 18.1 4.7 0.0028 17.5 4.7 1.4 1 0 0 1 1 1 1 Double-strand recombination repair protein Syntaxin-6_N PF09177.11 OWF53422.1 - 0.0023 18.5 6.6 0.0023 18.5 6.6 1.7 2 0 0 2 2 1 1 Syntaxin 6, N-terminal ADIP PF11559.8 OWF53422.1 - 0.015 15.4 9.0 0.035 14.2 9.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 OWF53422.1 - 0.021 15.0 5.4 0.021 15.0 5.4 1.7 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 CENP-Q PF13094.6 OWF53422.1 - 0.064 13.5 8.6 0.027 14.7 6.2 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3450 PF11932.8 OWF53422.1 - 0.097 12.0 6.8 0.18 11.0 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 OWF53422.1 - 0.12 12.5 15.5 0.12 12.5 11.3 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Striatin PF08232.12 OWF53422.1 - 0.24 12.0 11.7 0.035 14.7 7.5 1.7 2 1 0 2 2 2 0 Striatin family APG6_N PF17675.1 OWF53422.1 - 0.26 11.8 19.3 0.99 9.9 19.6 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Remorin_C PF03763.13 OWF53422.1 - 0.39 10.6 12.2 0.88 9.5 12.2 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region DUF724 PF05266.14 OWF53422.1 - 0.51 10.1 9.4 1.1 9.1 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TSNAXIP1_N PF15739.5 OWF53422.1 - 1.4 9.3 14.0 0.12 12.8 3.1 2.4 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus TMPIT PF07851.13 OWF53422.1 - 1.7 7.8 6.5 2.7 7.2 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein RecG_N PF17190.4 OWF53422.1 - 2.5 8.9 8.5 16 6.3 5.8 2.8 3 0 0 3 3 3 0 RecG N-terminal helical domain DivIC PF04977.15 OWF53422.1 - 3.1 7.6 16.5 0.049 13.4 7.2 2.6 2 1 1 3 3 3 0 Septum formation initiator GrpE PF01025.19 OWF53422.1 - 6.4 6.4 12.2 14 5.3 12.2 1.5 1 0 0 1 1 1 0 GrpE TPR_2 PF07719.17 OWF53423.1 - 4.8e-16 57.5 2.4 2e-07 30.6 0.9 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF53423.1 - 4.2e-12 45.3 1.7 1.5e-05 24.6 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF53423.1 - 4.6e-12 46.3 0.1 0.0013 19.2 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF53423.1 - 3e-11 43.1 0.1 9.2e-05 22.9 0.0 5.1 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF53423.1 - 5.9e-10 38.6 1.6 0.00011 22.1 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF53423.1 - 1.6e-06 27.7 0.2 0.082 13.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF53423.1 - 3.8e-06 27.0 0.4 2.6e-05 24.3 0.1 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF53423.1 - 3.8e-06 27.4 0.1 0.00016 22.3 0.0 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF53423.1 - 5.1e-06 26.6 4.6 7.7e-06 26.0 3.2 2.2 3 0 0 3 3 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OWF53423.1 - 1.4e-05 24.7 3.2 0.00024 20.7 0.3 3.2 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 OWF53423.1 - 0.00017 21.8 3.3 0.0061 16.8 0.2 3.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF53423.1 - 0.00073 20.0 9.0 0.19 12.5 0.2 5.4 7 0 0 7 7 5 1 Tetratricopeptide repeat NARP1 PF12569.8 OWF53423.1 - 0.0014 17.7 3.2 0.011 14.6 2.2 2.5 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 OWF53423.1 - 0.0021 17.5 0.1 1.3 8.3 0.0 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_3 PF07720.12 OWF53423.1 - 0.0029 17.6 1.8 0.0029 17.6 1.8 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF53423.1 - 0.003 17.8 0.8 9.3 6.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF53423.1 - 0.0049 16.9 0.9 0.12 12.4 0.1 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat YfiO PF13525.6 OWF53423.1 - 0.067 12.9 2.5 1.4 8.6 1.5 2.6 1 1 0 1 1 1 0 Outer membrane lipoprotein Alkyl_sulf_dimr PF14863.6 OWF53423.1 - 0.14 12.6 2.6 1.2 9.6 0.0 2.9 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation Mad3_BUB1_I PF08311.12 OWF53423.1 - 0.39 10.7 4.1 6.4 6.8 1.1 3.5 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_10 PF13374.6 OWF53423.1 - 3.9 7.5 6.2 2.7 8.0 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat UPF0020 PF01170.18 OWF53424.1 - 9e-10 38.6 0.0 6.1e-09 35.8 0.0 2.2 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OWF53424.1 - 2.9e-05 23.9 0.0 0.0034 17.1 0.0 2.4 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 OWF53424.1 - 8.2e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 OWF53424.1 - 0.00033 20.4 0.2 0.0017 18.1 0.0 2.2 3 0 0 3 3 3 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_11 PF08241.12 OWF53424.1 - 0.018 15.7 0.0 0.047 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF53424.1 - 0.025 14.2 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PI31_Prot_N PF11566.8 OWF53425.1 - 3.6e-23 82.1 0.0 7e-23 81.2 0.0 1.5 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OWF53425.1 - 0.0016 19.6 17.4 0.0016 19.6 17.4 2.4 2 1 1 3 3 3 1 PI31 proteasome regulator TRAPPC9-Trs120 PF08626.11 OWF53426.1 - 1.1e-41 142.4 4.6 1.2e-18 66.1 0.0 5.3 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_1 PF00515.28 OWF53426.1 - 0.11 12.3 0.1 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF53426.1 - 0.22 11.8 0.1 4.5 7.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Macoilin PF09726.9 OWF53426.1 - 1.2 7.6 10.8 1.8 7.0 10.8 1.2 1 0 0 1 1 1 0 Macoilin family Tai4 PF16695.5 OWF53427.1 - 5.2e-24 84.6 42.9 4.2e+02 1.6 0.0 33.6 39 0 0 39 39 39 0 Type VI secretion system (T6SS), amidase immunity protein Otopetrin PF03189.13 OWF53428.1 - 5.2e-107 358.4 26.5 2.1e-106 356.5 26.5 1.8 1 1 0 1 1 1 1 Otopetrin PDZ PF00595.24 OWF53429.1 - 1.1e-66 221.1 17.0 2.9e-18 66.0 0.5 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 OWF53429.1 - 3e-35 119.9 6.9 9.3e-09 35.0 0.1 4.7 4 0 0 4 4 4 4 PDZ domain LRR_8 PF13855.6 OWF53429.1 - 4e-33 113.0 41.6 1.1e-07 31.4 0.5 6.7 3 2 3 7 7 7 7 Leucine rich repeat PDZ_2 PF13180.6 OWF53429.1 - 5e-21 74.8 8.2 4.5e-05 23.7 0.0 4.9 4 0 0 4 4 4 4 PDZ domain LRR_4 PF12799.7 OWF53429.1 - 3e-20 72.0 52.9 0.00066 20.0 2.6 8.1 6 2 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF53429.1 - 0.00056 19.4 25.2 0.06 12.9 1.1 4.8 1 1 4 5 5 5 4 Leucine-rich repeat PDZ_4 PF17816.1 OWF53429.1 - 0.0043 17.4 0.5 3 8.3 0.0 4.2 4 0 0 4 4 4 1 PDZ domain PSS PF03034.15 OWF53430.1 - 1.2e-107 359.7 22.8 1.2e-107 359.7 22.8 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase DUF5518 PF17647.1 OWF53430.1 - 0.13 12.4 4.9 0.24 11.5 1.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5518) Ubiq_cyt_C_chap PF03981.12 OWF53431.1 - 2.9e-27 95.5 0.5 4.2e-27 94.9 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone CobS_N PF12556.8 OWF53431.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal TIR_2 PF13676.6 OWF53432.1 - 5.2e-07 30.3 0.1 1.7e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OWF53432.1 - 3.7e-06 26.9 0.5 3.7e-06 26.9 0.5 2.0 2 0 0 2 2 2 1 TIR domain TPR_7 PF13176.6 OWF53432.1 - 0.062 13.3 0.0 3 8.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF53432.1 - 0.27 11.1 11.7 1.1 9.2 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat s48_45 PF07422.13 OWF53432.1 - 0.38 11.3 11.6 0.074 13.6 0.8 3.5 3 1 0 3 3 3 0 Sexual stage antigen s48/45 domain HTH_26 PF13443.6 OWF53433.1 - 0.0004 20.7 13.6 3.7 8.0 0.5 5.4 1 1 3 4 4 4 3 Cro/C1-type HTH DNA-binding domain CcdA PF07362.12 OWF53433.1 - 0.0032 17.9 4.4 3.5 8.1 0.2 3.9 1 1 1 3 3 3 1 Post-segregation antitoxin CcdA Omptin PF01278.20 OWF53433.1 - 0.02 13.9 2.1 1.9 7.4 0.1 2.1 1 1 1 2 2 2 0 Omptin family DUF2148 PF09918.9 OWF53433.1 - 0.05 13.6 4.0 9.1 6.4 0.1 3.5 1 1 2 4 4 4 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) HTH_10 PF04967.12 OWF53433.1 - 0.31 10.9 18.9 35 4.3 0.1 7.5 1 1 8 9 9 9 0 HTH DNA binding domain DUF4675 PF15720.5 OWF53433.1 - 0.37 10.5 13.9 2.4 7.9 1.8 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4675) Big_3_2 PF12245.8 OWF53433.1 - 0.59 10.4 10.1 13 6.1 9.7 2.4 1 1 0 1 1 1 0 Bacterial Ig-like domain SinI PF08671.10 OWF53433.1 - 2.4 8.0 10.4 28 4.6 0.0 5.3 8 0 0 8 8 8 0 Anti-repressor SinI Toxin_10 PF05431.11 OWF53433.1 - 8.5 5.8 15.8 2.9 7.3 9.2 2.4 1 1 2 3 3 3 0 Insecticidal Crystal Toxin, P42 OATP PF03137.20 OWF53434.1 - 3e-151 504.4 24.7 3.7e-151 504.1 24.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OWF53434.1 - 9.2e-25 87.3 23.9 9.2e-25 87.3 23.9 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 OWF53434.1 - 2.4e-06 27.6 10.5 6e-06 26.3 10.5 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF53434.1 - 0.001 19.0 4.3 0.0038 17.2 4.3 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain SLC3A2_N PF16028.5 OWF53434.1 - 6.2 6.5 6.1 6.2 6.4 0.6 2.7 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus P4Ha_N PF08336.11 OWF53435.1 - 5.8e-18 65.2 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 OWF53435.1 - 3e-14 53.7 0.0 6.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 OWF53436.1 - 5e-19 68.7 0.0 9.7e-19 67.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF53436.1 - 3.6e-11 42.8 0.0 5.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF53436.1 - 0.0015 18.5 0.0 0.0074 16.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF53436.1 - 0.0053 15.6 0.1 0.006 15.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF53436.1 - 0.065 12.6 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 OWF53436.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family PKK PF12474.8 OWF53437.1 - 0.0029 17.8 1.4 0.55 10.4 0.6 2.0 1 1 1 2 2 2 2 Polo kinase kinase DUF2443 PF10398.9 OWF53437.1 - 0.087 12.9 9.7 30 4.7 0.1 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF2443) DUF1199 PF06712.11 OWF53437.1 - 0.71 9.9 7.8 23 5.1 0.1 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1199) Aft1_HRR PF11787.8 OWF53437.1 - 3.8 8.8 10.6 12 7.2 4.4 3.0 1 1 1 2 2 2 0 Aft1 HRR domain Ogr_Delta PF04606.12 OWF53437.1 - 4.1 7.5 12.3 14 5.7 0.1 4.0 4 1 0 4 4 4 0 Ogr/Delta-like zinc finger ETS_PEA3_N PF04621.13 OWF53437.1 - 4.1 7.2 9.7 4.9 6.9 9.7 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain PKK PF12474.8 OWF53438.1 - 0.0094 16.1 3.3 0.12 12.5 0.4 2.0 1 1 1 2 2 2 2 Polo kinase kinase Tis11B_N PF04553.12 OWF53438.1 - 0.034 14.7 4.7 0.045 14.3 4.7 1.3 1 0 0 1 1 1 0 Tis11B like protein, N terminus CysA_C_terminal PF17850.1 OWF53439.1 - 4.3e-07 30.4 8.2 21 5.8 0.0 7.1 3 2 4 7 7 7 0 CysA C-terminal regulatory domain BON PF04972.17 OWF53439.1 - 1.6e-05 25.1 13.0 1.6 9.1 0.2 5.9 1 1 3 4 4 4 2 BON domain Bactofilin PF04519.13 OWF53439.1 - 9.7e-05 22.6 19.4 0.035 14.4 7.7 3.0 1 1 2 3 3 3 3 Polymer-forming cytoskeletal TA_inhibitor PF17574.2 OWF53439.1 - 0.013 15.5 18.5 23 5.1 0.2 6.5 1 1 5 6 6 6 0 Inhibitor of toxin/antitoxin system (Gp4.5) Flg_hook PF02120.16 OWF53439.1 - 0.029 14.2 0.5 11 6.0 0.0 3.5 2 1 0 3 3 3 0 Flagellar hook-length control protein FliK Malectin PF11721.8 OWF53439.1 - 0.051 13.7 3.7 12 6.0 0.1 3.2 1 1 1 3 3 3 0 Malectin domain CAF1-p150_C2 PF15539.6 OWF53439.1 - 0.09 12.2 3.6 0.098 12.1 0.1 2.5 1 1 2 3 3 3 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Colicin_E5 PF12106.8 OWF53439.1 - 0.88 9.9 4.5 7.1 7.0 0.1 3.1 1 1 2 3 3 3 0 Colicin E5 ribonuclease domain DUF3421 PF11901.8 OWF53439.1 - 1.4 8.9 8.7 12 5.9 2.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3421) NB-ARC PF00931.22 OWF53439.1 - 3 6.9 11.2 38 3.3 0.1 4.1 1 1 1 2 2 2 0 NB-ARC domain TbpB_B_D PF01298.18 OWF53439.1 - 3.1 8.2 15.8 2.2e+03 -1.0 15.7 2.9 1 1 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Myco_19_kDa PF05481.12 OWF53439.1 - 3.9 7.8 11.6 2.4 8.5 3.8 2.7 1 1 2 3 3 3 0 Mycobacterium 19 kDa lipoprotein antigen DUF1658 PF07871.11 OWF53439.1 - 5.7 7.0 17.1 2.5e+02 1.9 0.0 8.3 10 0 0 10 10 10 0 Protein of unknown function (DUF1658) Trypsin PF00089.26 OWF53440.1 - 5.8e-66 222.5 6.4 7.9e-66 222.0 6.4 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 OWF53440.1 - 5.7e-09 36.4 0.5 1.1e-08 35.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 OWF53440.1 - 5.3e-05 24.1 0.8 0.00022 22.1 0.8 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF53441.1 - 3.3e-63 213.5 6.6 4.5e-63 213.0 6.6 1.2 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 OWF53441.1 - 5.2e-06 26.2 0.3 0.1 12.1 0.0 2.4 1 1 0 2 2 2 2 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 OWF53441.1 - 9.6e-06 26.0 0.2 1.7e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Death PF00531.22 OWF53442.1 - 1.4e-11 44.4 0.5 3.4e-05 23.9 0.1 2.9 2 0 0 2 2 2 2 Death domain COR PF16095.5 OWF53442.1 - 2e-11 44.1 0.0 5.9e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF53442.1 - 4.1e-11 43.2 0.1 4.7e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF53442.1 - 0.00055 19.6 0.1 0.19 11.3 0.0 2.7 2 0 0 2 2 2 2 Ras family AAA PF00004.29 OWF53442.1 - 0.0024 18.3 0.0 0.19 12.1 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 OWF53442.1 - 0.0041 16.6 0.1 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OWF53442.1 - 0.021 14.5 0.0 0.074 12.8 0.0 1.9 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OWF53442.1 - 0.034 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 OWF53442.1 - 0.041 14.4 0.1 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Ank_2 PF12796.7 OWF53442.1 - 0.043 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) MMR_HSR1 PF01926.23 OWF53442.1 - 0.053 13.6 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DAP3 PF10236.9 OWF53442.1 - 0.13 11.4 0.1 0.44 9.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Roc PF08477.13 OWF53443.1 - 6e-11 42.6 0.0 1.9e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF53443.1 - 8.1e-10 38.8 0.5 1.7e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Ras PF00071.22 OWF53443.1 - 2.8e-06 27.0 0.1 0.0031 17.1 0.0 2.7 2 0 0 2 2 2 2 Ras family Ank_2 PF12796.7 OWF53443.1 - 4.2e-06 27.3 0.1 4.3e-05 24.0 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF53443.1 - 6.9e-05 23.1 0.2 0.77 10.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Death PF00531.22 OWF53443.1 - 0.00034 20.7 0.0 0.003 17.7 0.0 2.6 2 1 0 2 2 2 1 Death domain AAA_16 PF13191.6 OWF53443.1 - 0.0031 17.9 0.0 0.0084 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OWF53443.1 - 0.0075 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase 14-3-3 PF00244.20 OWF53443.1 - 0.011 15.3 0.3 0.021 14.4 0.3 1.4 1 0 0 1 1 1 0 14-3-3 protein Ank_4 PF13637.6 OWF53443.1 - 0.02 15.5 0.1 0.064 13.9 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) HEPN_DZIP3 PF18738.1 OWF53443.1 - 0.025 14.3 0.2 6.3 6.5 0.0 2.6 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN DUF2951 PF11166.8 OWF53443.1 - 0.043 14.0 0.1 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) VirE PF05272.11 OWF53443.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E ABC_tran PF00005.27 OWF53443.1 - 0.45 11.0 3.4 0.53 10.8 0.1 2.6 1 1 1 2 2 2 0 ABC transporter COR PF16095.5 OWF53444.1 - 7.4e-12 45.5 0.1 1.5e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF53444.1 - 5e-09 36.4 0.0 2e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 OWF53444.1 - 1.8e-06 28.4 0.0 5.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53444.1 - 2.1e-06 28.1 0.1 0.0013 19.2 0.0 3.1 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ras PF00071.22 OWF53444.1 - 5.4e-05 22.8 0.2 0.15 11.7 0.1 3.3 3 0 0 3 3 3 2 Ras family Death PF00531.22 OWF53444.1 - 0.0025 17.9 0.0 0.012 15.8 0.0 2.1 1 0 0 1 1 1 1 Death domain AAA_22 PF13401.6 OWF53444.1 - 0.0085 16.4 0.2 0.84 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF53444.1 - 0.011 16.1 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OWF53444.1 - 0.021 15.4 0.6 3.6 8.1 0.0 4.0 4 0 0 4 4 4 0 AAA domain Ank_3 PF13606.6 OWF53444.1 - 0.06 13.9 0.1 8.5 7.3 0.0 4.1 4 0 0 4 4 3 0 Ankyrin repeat ABC_tran PF00005.27 OWF53444.1 - 0.085 13.4 1.4 0.45 11.0 0.3 2.8 3 1 0 3 3 3 0 ABC transporter ATP_bind_1 PF03029.17 OWF53444.1 - 0.09 12.5 0.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ank_5 PF13857.6 OWF53444.1 - 0.092 13.1 0.0 0.47 10.8 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Dynamin_N PF00350.23 OWF53444.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.9 1 1 0 1 1 1 0 Dynamin family RsgA_GTPase PF03193.16 OWF53444.1 - 0.15 12.0 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase RVT_1 PF00078.27 OWF53445.1 - 2.6e-34 118.7 0.6 4.1e-34 118.0 0.6 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Scm3 PF10384.9 OWF53445.1 - 0.14 11.9 0.6 16 5.3 0.1 2.9 2 0 0 2 2 2 0 Centromere protein Scm3 Roc PF08477.13 OWF53446.1 - 8.3e-12 45.4 0.0 6.5e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 OWF53446.1 - 3.9e-10 39.8 0.1 9e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_5 PF13857.6 OWF53446.1 - 5.9e-06 26.5 0.0 0.00078 19.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ras PF00071.22 OWF53446.1 - 9.6e-06 25.3 0.3 0.0081 15.8 0.0 2.8 2 0 0 2 2 2 2 Ras family Ank_2 PF12796.7 OWF53446.1 - 7.3e-05 23.3 0.0 0.00027 21.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53446.1 - 0.0002 21.8 0.0 0.0046 17.5 0.0 3.1 2 1 1 3 3 2 1 Ankyrin repeats (many copies) Death PF00531.22 OWF53446.1 - 0.00021 21.4 0.0 0.00063 19.9 0.0 1.9 1 0 0 1 1 1 1 Death domain Ank PF00023.30 OWF53446.1 - 0.0024 18.2 0.5 3.2 8.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OWF53446.1 - 0.028 15.0 0.5 13 6.7 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat AAA_16 PF13191.6 OWF53446.1 - 0.062 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OWF53446.1 - 0.096 13.0 0.0 0.37 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain SopA PF13981.6 OWF53446.1 - 0.29 11.6 1.5 0.69 10.4 0.1 2.4 2 0 0 2 2 2 0 SopA-like central domain COR PF16095.5 OWF53447.1 - 1.2e-09 38.3 0.1 2.4e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 OWF53447.1 - 1.5e-08 34.9 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Death PF00531.22 OWF53447.1 - 3.4e-05 23.9 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Death domain Ras PF00071.22 OWF53447.1 - 7e-05 22.5 0.2 0.00026 20.6 0.0 1.9 2 0 0 2 2 2 1 Ras family ABC_membrane PF00664.23 OWF53448.1 - 4.4e-65 220.1 40.9 2.4e-36 125.8 15.1 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF53448.1 - 4.8e-50 169.6 0.1 7.4e-25 88.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF53448.1 - 4.4e-09 36.1 6.2 0.0077 15.7 0.2 4.5 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OWF53448.1 - 1e-05 25.6 1.4 0.089 12.9 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF53448.1 - 0.001 19.0 2.3 0.61 10.0 0.2 3.0 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OWF53448.1 - 0.0012 19.3 0.1 0.46 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OWF53448.1 - 0.0019 17.9 2.2 0.96 9.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OWF53448.1 - 0.021 15.1 1.0 6.1 7.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OWF53448.1 - 0.057 13.1 0.8 12 5.5 0.2 3.0 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OWF53448.1 - 0.085 12.6 1.1 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 OWF53448.1 - 0.14 12.7 0.2 16 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OWF53448.1 - 0.24 11.4 5.1 0.95 9.5 1.3 2.6 2 0 0 2 2 2 0 Dynamin family MCM2_N PF12619.8 OWF53448.1 - 0.28 11.5 4.0 0.15 12.3 0.9 2.1 3 0 0 3 3 2 0 Mini-chromosome maintenance protein 2 NB-ARC PF00931.22 OWF53448.1 - 0.28 10.3 2.4 5.6 6.1 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 OWF53448.1 - 0.37 10.0 1.1 7 5.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 OWF53448.1 - 0.68 10.0 6.4 0.83 9.7 0.2 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 OWF53448.1 - 0.76 10.2 5.2 15 6.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain zf-H2C2_2 PF13465.6 OWF53449.1 - 4.2e-49 162.9 33.9 1.1e-08 35.1 0.1 10.1 9 1 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 OWF53449.1 - 1.9e-41 138.2 66.5 7e-07 29.4 2.1 10.1 10 0 0 10 10 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF53449.1 - 4.7e-30 101.7 58.8 0.00047 20.8 1.7 9.9 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 OWF53449.1 - 1.1e-10 41.5 48.9 0.12 12.8 0.7 10.6 10 0 0 10 10 10 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF53449.1 - 2.9e-07 30.6 44.5 0.43 10.9 0.9 10.0 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF53449.1 - 0.00026 20.9 0.1 0.00026 20.9 0.1 10.7 10 1 0 10 10 10 2 C2H2-type zinc finger C1_1 PF00130.22 OWF53449.1 - 0.00034 20.4 34.0 0.31 11.0 2.4 5.4 4 1 0 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.12 OWF53449.1 - 0.0006 20.0 36.6 0.09 13.1 3.9 5.6 4 1 2 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 OWF53449.1 - 0.0062 16.3 5.9 1.7 8.5 0.1 4.8 5 0 0 5 5 5 1 GAGA factor Zn-ribbon_8 PF09723.10 OWF53449.1 - 0.007 16.5 34.1 0.23 11.6 1.9 6.4 4 2 2 6 6 6 3 Zinc ribbon domain zinc_ribbon_15 PF17032.5 OWF53449.1 - 0.012 16.3 31.8 1.1 10.1 0.7 6.2 2 1 6 8 8 8 0 zinc-ribbon family zf-C2H2_2 PF12756.7 OWF53449.1 - 0.28 11.5 43.3 3.7 7.9 4.2 8.1 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 OWF53449.1 - 0.34 11.1 34.1 27 5.0 1.2 5.0 3 1 0 3 3 3 0 FYVE zinc finger zf-C2H2_9 PF16293.5 OWF53449.1 - 0.42 10.5 7.3 35 4.4 0.1 5.9 4 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) DUF3268 PF11672.8 OWF53449.1 - 0.52 10.6 22.9 5.1 7.5 1.0 4.5 4 0 0 4 4 4 0 zinc-finger-containing domain zf-BED PF02892.15 OWF53449.1 - 0.68 10.0 40.7 0.47 10.5 0.6 7.0 3 3 4 7 7 7 0 BED zinc finger DZR PF12773.7 OWF53449.1 - 0.92 9.6 27.5 18 5.5 1.4 4.9 2 1 0 2 2 1 0 Double zinc ribbon zf-C2H2_8 PF15909.5 OWF53449.1 - 1 9.7 25.7 0.25 11.7 0.7 5.3 1 1 4 5 5 5 0 C2H2-type zinc ribbon ADK_lid PF05191.14 OWF53449.1 - 1.3 9.1 24.4 3.2 7.8 3.5 6.3 5 2 0 5 5 5 0 Adenylate kinase, active site lid zf-MYST PF17772.1 OWF53449.1 - 9.1 6.0 10.3 22 4.8 0.4 4.4 4 0 0 4 4 4 0 MYST family zinc finger domain DUF4621 PF15414.6 OWF53450.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) DUF5599 PF18141.1 OWF53451.1 - 0.00022 21.4 0.0 4.7 7.5 0.0 4.4 1 1 2 3 3 3 1 Domain of unknown function (DUF5599) NADH_dehy_S2_C PF06444.11 OWF53451.1 - 0.0048 17.4 28.9 0.73 10.4 0.3 8.7 2 1 9 11 11 11 3 NADH dehydrogenase subunit 2 C-terminus MCC-bdg_PDZ PF10506.9 OWF53451.1 - 0.044 13.8 4.1 75 3.5 0.1 4.8 5 2 1 6 6 6 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Requiem_N PF14051.6 OWF53451.1 - 1.3 9.2 22.2 6.2 7.1 0.4 5.0 1 1 6 7 7 7 0 N-terminal domain of DPF2/REQ. SIM_C PF06621.12 OWF53451.1 - 5.2 7.0 11.3 1.5e+04 -4.4 11.3 4.5 1 1 0 1 1 1 0 Single-minded protein C-terminus DUF5599 PF18141.1 OWF53452.1 - 3e-05 24.2 0.0 4 7.7 0.0 4.1 1 1 2 3 3 3 3 Domain of unknown function (DUF5599) NADH_dehy_S2_C PF06444.11 OWF53452.1 - 3.2e-05 24.3 23.3 0.57 10.7 0.2 7.4 2 1 7 9 9 9 3 NADH dehydrogenase subunit 2 C-terminus DUF2625 PF10946.8 OWF53452.1 - 0.036 13.1 0.8 12 4.9 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF2625 Requiem_N PF14051.6 OWF53452.1 - 0.19 12.0 17.8 1.3 9.2 1.4 3.6 1 1 3 4 4 4 0 N-terminal domain of DPF2/REQ. RAG2_PHD PF13341.6 OWF53452.1 - 6.8 6.8 10.0 12 6.0 1.0 2.6 1 1 1 2 2 2 0 RAG2 PHD domain SIM_C PF06621.12 OWF53452.1 - 8.4 6.3 9.9 46 3.9 1.8 3.9 1 1 1 2 2 2 0 Single-minded protein C-terminus Tctex-1 PF03645.13 OWF53454.1 - 5.7e-25 87.5 0.2 8.3e-25 87.0 0.2 1.3 1 0 0 1 1 1 1 Tctex-1 family Ribonuc_red_lgN PF00317.21 OWF53454.1 - 0.061 13.3 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Ion_trans PF00520.31 OWF53455.1 - 2e-29 102.5 8.4 3e-29 102.0 8.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF53455.1 - 6e-12 45.4 3.5 6e-12 45.4 3.5 2.4 2 1 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 OWF53455.1 - 5.3e-08 32.8 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NPV_P10 PF05531.12 OWF53455.1 - 0.081 13.4 0.1 0.79 10.2 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_C1 PF00112.23 OWF53456.1 - 2.5e-87 292.6 2.2 3.3e-87 292.2 2.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF53456.1 - 2.4e-13 50.3 0.4 4.3e-13 49.5 0.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF53456.1 - 3.7e-06 26.0 3.4 0.00094 18.1 0.2 2.5 3 0 0 3 3 3 2 Peptidase C1-like family Meiosis_expr PF15163.6 OWF53456.1 - 0.13 12.9 0.5 0.54 10.9 0.1 2.2 2 0 0 2 2 2 0 Meiosis-expressed Peptidase_M4_C PF02868.15 OWF53457.1 - 6.9e-30 104.1 0.1 1.1e-29 103.5 0.1 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 OWF53457.1 - 6.9e-25 88.2 0.0 3e-24 86.2 0.0 2.1 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain PepSY PF03413.19 OWF53457.1 - 7.3e-06 26.4 2.0 3.1e-05 24.4 0.1 2.8 3 0 0 3 3 3 1 Peptidase propeptide and YPEB domain FTP PF07504.13 OWF53457.1 - 4.2e-05 23.3 0.9 0.00013 21.8 0.9 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_C1 PF00112.23 OWF53458.1 - 7.6e-87 291.0 4.7 9.8e-87 290.6 4.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF53458.1 - 3.2e-12 46.7 0.2 5.7e-12 45.9 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF53458.1 - 5.1e-06 25.5 1.6 0.0079 15.0 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Self-incomp_S1 PF05938.11 OWF53458.1 - 0.026 15.1 0.0 0.061 13.9 0.0 1.6 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 Peptidase_C1 PF00112.23 OWF53459.1 - 3.2e-84 282.4 7.9 4.3e-84 282.0 7.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF53459.1 - 8.4e-13 48.5 0.9 1.6e-12 47.6 0.9 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF53459.1 - 5.3e-06 25.5 1.8 0.011 14.5 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 OWF53460.1 - 1.7e-75 253.8 6.0 2.3e-75 253.4 6.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF53460.1 - 4.8e-16 58.9 0.7 1.1e-15 57.8 0.7 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF53460.1 - 7.8e-05 21.6 2.5 0.01 14.7 0.6 2.2 2 0 0 2 2 2 2 Peptidase C1-like family SGS PF05002.15 OWF53460.1 - 0.08 13.1 1.4 0.55 10.4 1.4 2.1 1 1 1 2 2 2 0 SGS domain SPARC_Ca_bdg PF10591.9 OWF53461.1 - 0.22 11.9 3.0 0.68 10.3 3.0 1.9 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Penaeidin PF05927.11 OWF53462.1 - 0.14 12.9 1.0 11 6.9 0.1 2.2 2 0 0 2 2 2 0 Penaeidin Sec1 PF00995.23 OWF53463.1 - 0.032 13.5 0.5 0.044 13.0 0.5 1.2 1 0 0 1 1 1 0 Sec1 family C1q PF00386.21 OWF53464.1 - 4.6e-22 78.6 0.1 9e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF53464.1 - 0.0012 18.8 0.8 0.0023 17.8 0.8 1.4 1 0 0 1 1 1 1 BclA C-terminal domain ARGLU PF15346.6 OWF53464.1 - 0.018 14.9 4.3 0.024 14.5 4.3 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 PI3K_P85_iSH2 PF16454.5 OWF53464.1 - 0.041 13.5 4.2 0.061 12.9 4.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HAUS-augmin3 PF14932.6 OWF53464.1 - 0.15 11.6 4.7 0.21 11.1 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF16 PF01519.16 OWF53464.1 - 1.4 9.4 4.8 5.7 7.5 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 OWF53464.1 - 5.6 7.7 9.2 7.1 7.3 4.5 2.3 1 1 1 2 2 2 0 SlyX C1q PF00386.21 OWF53465.1 - 1.3e-12 48.0 0.1 2.8e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 OWF53466.1 - 1.5e-13 51.1 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 C1q domain RGI_lyase PF18370.1 OWF53466.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain Zona_pellucida PF00100.23 OWF53467.1 - 1.5e-07 31.5 1.8 2.3e-07 30.9 1.8 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain ECSCR PF15820.5 OWF53467.1 - 0.011 15.5 0.3 0.024 14.5 0.3 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator OAD_gamma PF04277.13 OWF53467.1 - 0.082 13.5 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain I-set PF07679.16 OWF53468.1 - 4.8e-18 65.0 0.2 0.0098 15.9 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF53468.1 - 4.2e-17 62.5 5.8 0.01 16.4 0.0 6.6 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 OWF53468.1 - 0.00029 21.1 0.2 3 8.2 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain DUF3710 PF12502.8 OWF53468.1 - 0.0072 16.0 0.1 47 3.6 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3710) FAM176 PF14851.6 OWF53468.1 - 0.018 14.7 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 FAM176 family TMEM154 PF15102.6 OWF53468.1 - 0.033 14.1 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Receptor_2B4 PF11465.8 OWF53468.1 - 0.14 12.4 0.2 20 5.5 0.0 3.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 YebF PF13995.6 OWF53469.1 - 0.063 13.3 0.3 0.17 11.9 0.3 1.7 1 0 0 1 1 1 0 YebF-like protein VWA_2 PF13519.6 OWF53470.1 - 1.9e-06 28.5 0.1 3.3e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OWF53470.1 - 7.2e-06 26.4 0.1 2.9e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF444 PF04285.12 OWF53470.1 - 0.18 10.8 0.2 0.33 10.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Trypsin_2 PF13365.6 OWF53471.1 - 0.083 13.8 0.0 0.24 12.3 0.0 1.7 2 0 0 2 2 2 0 Trypsin-like peptidase domain Glyco_transf_11 PF01531.16 OWF53472.1 - 4.5e-43 147.6 2.5 9.6e-43 146.5 2.5 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 11 VWD PF00094.25 OWF53474.1 - 2.2e-06 28.0 0.5 1.3e-05 25.5 0.5 2.4 1 1 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 OWF53474.1 - 0.0054 17.1 11.2 0.0054 17.1 11.2 3.0 3 0 0 3 3 3 1 EGF-like domain Mid2 PF04478.12 OWF53474.1 - 0.0073 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EGF_Tenascin PF18720.1 OWF53474.1 - 0.0089 16.1 5.3 0.0089 16.1 5.3 2.5 2 0 0 2 2 2 1 Tenascin EGF domain DUF3827 PF12877.7 OWF53474.1 - 0.058 11.8 0.0 0.089 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EGF_alliinase PF04863.13 OWF53474.1 - 0.078 13.4 2.4 0.33 11.4 2.4 2.1 1 0 0 1 1 1 0 Alliinase EGF-like domain Lectin_C PF00059.21 OWF53475.1 - 2.1e-06 28.4 0.3 8.3e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 Lectin C-type domain Flot PF15975.5 OWF53475.1 - 0.041 14.1 0.4 0.094 12.9 0.4 1.6 1 0 0 1 1 1 0 Flotillin UL45 PF05473.12 OWF53475.1 - 0.11 12.1 0.7 0.24 11.0 0.2 1.8 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Glyco_transf_11 PF01531.16 OWF53476.1 - 1.8e-38 132.5 0.5 3.5e-38 131.5 0.5 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 11 Forkhead PF00250.18 OWF53477.1 - 0.07 13.4 0.5 0.32 11.3 0.3 2.2 1 1 1 2 2 2 0 Forkhead domain Glyco_transf_11 PF01531.16 OWF53478.1 - 2.5e-16 59.8 1.1 5.7e-16 58.6 1.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 11 RP-C_C PF11800.8 OWF53478.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Late_protein_L2 PF00513.18 OWF53478.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Late Protein L2 ABC_membrane PF00664.23 OWF53482.1 - 4.1e-67 226.7 33.8 1e-37 130.3 8.4 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF53482.1 - 7.6e-52 175.5 5.8 5.7e-30 104.6 0.0 3.4 4 1 0 4 4 2 2 ABC transporter SMC_N PF02463.19 OWF53482.1 - 3.3e-09 36.5 7.3 0.028 13.9 1.5 4.5 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OWF53482.1 - 2.4e-08 34.1 0.8 0.24 11.2 0.2 4.8 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OWF53482.1 - 3.1e-08 33.7 1.3 0.0052 16.9 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF53482.1 - 6.2e-06 26.2 3.8 0.0021 18.0 0.9 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OWF53482.1 - 1.3e-05 24.8 2.4 0.07 12.9 0.2 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OWF53482.1 - 0.00013 21.4 1.5 0.14 11.5 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MeaB PF03308.16 OWF53482.1 - 0.00014 20.9 1.1 0.084 11.8 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OWF53482.1 - 0.001 19.5 0.1 1.8 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain KAP_NTPase PF07693.14 OWF53482.1 - 0.0011 18.3 0.0 0.042 13.1 0.0 2.8 2 0 0 2 2 2 1 KAP family P-loop domain DUF87 PF01935.17 OWF53482.1 - 0.0019 18.4 6.2 0.41 10.7 0.4 3.0 2 1 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 OWF53482.1 - 0.0034 17.3 0.9 0.88 9.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 OWF53482.1 - 0.0034 16.9 0.2 2.6 7.5 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 OWF53482.1 - 0.0037 17.5 0.1 2.9 8.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 OWF53482.1 - 0.0041 17.2 0.0 0.0041 17.2 0.0 3.6 5 0 0 5 5 3 1 Dynamin family Septin PF00735.18 OWF53482.1 - 0.0064 15.8 0.3 3 7.1 0.0 2.9 3 0 0 3 3 3 1 Septin ATP_bind_1 PF03029.17 OWF53482.1 - 0.0072 16.1 0.8 0.52 10.1 0.0 3.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 OWF53482.1 - 0.01 16.2 0.1 10 6.5 0.0 3.2 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OWF53482.1 - 0.012 14.8 1.5 1.5 7.9 0.1 2.9 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 OWF53482.1 - 0.018 15.3 0.4 4.7 7.5 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 OWF53482.1 - 0.021 15.4 0.0 5 7.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 OWF53482.1 - 0.022 13.9 0.1 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 OWF53482.1 - 0.026 13.4 1.1 3.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 OWF53482.1 - 0.029 14.0 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OWF53482.1 - 0.05 12.6 1.6 0.56 9.2 0.2 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 OWF53482.1 - 0.058 13.1 0.3 8.1 6.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 OWF53482.1 - 0.07 12.6 1.3 13 5.2 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein TsaE PF02367.17 OWF53482.1 - 0.092 12.7 0.3 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 OWF53482.1 - 0.11 12.1 6.1 0.35 10.5 0.1 3.7 4 0 0 4 4 4 0 AAA ATPase domain Zeta_toxin PF06414.12 OWF53482.1 - 0.13 11.5 0.3 3.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 OWF53482.1 - 3 8.3 16.4 0.81 10.2 0.3 3.6 3 1 1 4 4 2 0 AAA domain Vasohibin PF14822.6 OWF53483.1 - 2.1e-105 351.4 0.0 2.6e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 Vasohibin RSD-2 PF07547.13 OWF53483.1 - 0.084 13.4 0.4 2.1 8.9 0.0 3.0 4 0 0 4 4 4 0 RSD-2 N-terminal domain DUF1653 PF07866.11 OWF53483.1 - 0.13 12.6 0.4 0.26 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) DUF2236 PF09995.9 OWF53485.1 - 7.1e-10 39.5 0.0 9.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DnaJ PF00226.31 OWF53486.1 - 6.4e-17 61.4 2.5 6.4e-17 61.4 2.5 2.6 2 0 0 2 2 2 1 DnaJ domain DUF4743 PF15916.5 OWF53486.1 - 0.16 12.0 3.3 1.9 8.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) ATG16 PF08614.11 OWF53487.1 - 0.00026 21.3 20.6 0.00026 21.3 20.6 4.1 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 OWF53487.1 - 0.077 12.6 45.7 0.095 12.3 9.2 4.4 3 1 1 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PhaC_N PF07167.13 OWF53487.1 - 0.12 12.1 0.9 0.46 10.1 0.1 2.4 2 1 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus YflT PF11181.8 OWF53487.1 - 0.16 12.5 0.2 0.16 12.5 0.2 3.6 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF3452 PF11934.8 OWF53487.1 - 0.36 10.4 3.2 1.3 8.6 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF1664 PF07889.12 OWF53487.1 - 0.42 10.7 32.8 0.71 9.9 0.3 4.5 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 OWF53487.1 - 0.43 10.6 58.9 0.12 12.4 3.3 4.2 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Tropomyosin PF00261.20 OWF53487.1 - 0.92 8.8 57.1 2.3 7.5 9.0 3.8 2 1 1 3 3 3 0 Tropomyosin TACC_C PF05010.14 OWF53487.1 - 1.1 9.0 48.9 0.076 12.8 19.3 3.3 2 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PspA_IM30 PF04012.12 OWF53487.1 - 1.8 8.1 37.2 0.14 11.7 18.3 3.4 3 0 0 3 3 3 0 PspA/IM30 family EzrA PF06160.12 OWF53487.1 - 2.1 6.4 45.7 0.081 11.1 19.2 3.2 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA DUF5634_N PF18672.1 OWF53488.1 - 1.3 8.8 8.3 1.7 8.4 0.2 3.6 1 1 3 4 4 4 0 Family of unknown function (DUF5634) Glyco_transf_7N PF13733.6 OWF53490.1 - 6.4e-42 142.4 0.0 1e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF53490.1 - 4.8e-23 80.6 0.1 8.7e-23 79.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Thioredoxin PF00085.20 OWF53491.1 - 3e-15 56.1 0.0 4.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin FAM176 PF14851.6 OWF53491.1 - 0.0011 18.7 0.9 0.0026 17.4 0.9 1.6 1 1 0 1 1 1 1 FAM176 family Thioredoxin_2 PF13098.6 OWF53491.1 - 0.11 13.0 0.2 0.49 10.9 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Zip PF02535.22 OWF53491.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ZU5 PF00791.20 OWF53492.1 - 2.3e-15 56.7 0.1 5.2e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 ZU5 domain UPA PF17217.3 OWF53492.1 - 1.5e-10 41.1 0.0 2.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 UPA domain Death PF00531.22 OWF53492.1 - 5.4e-07 29.7 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Death domain TssO PF17561.2 OWF53492.1 - 1.1 9.3 4.0 0.35 11.0 0.7 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO HECT PF00632.25 OWF53493.1 - 4.5e-17 62.5 0.0 4e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SAM_1 PF00536.30 OWF53494.1 - 9.3e-16 58.0 0.2 3.2e-08 33.9 0.0 2.8 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF53494.1 - 6.9e-10 38.9 0.0 3.8e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Asp_protease_2 PF13650.6 OWF53494.1 - 0.00018 22.1 0.0 0.00051 20.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease NCD1 PF04904.13 OWF53494.1 - 0.00083 19.3 0.1 0.59 10.2 0.0 2.6 2 1 0 2 2 2 2 NAB conserved region 1 (NCD1) gag-asp_proteas PF13975.6 OWF53494.1 - 0.0034 17.9 0.0 0.0072 16.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Spuma_A9PTase PF03539.14 OWF53494.1 - 0.007 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Spumavirus aspartic protease (A9) IGR PF09597.10 OWF53494.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 IGR protein motif GDP_Man_Dehyd PF16363.5 OWF53495.1 - 1.8e-157 524.0 0.1 2e-157 523.8 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OWF53495.1 - 4.7e-73 245.6 0.0 6.5e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OWF53495.1 - 7e-06 25.3 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OWF53495.1 - 0.012 14.8 0.0 0.042 13.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 OWF53495.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Forkhead PF00250.18 OWF53496.1 - 5.1e-40 135.6 0.0 8.5e-40 134.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain YbgS PF13985.6 OWF53496.1 - 0.1 12.9 3.8 0.096 13.0 2.7 1.5 1 1 0 1 1 1 0 YbgS-like protein Forkhead PF00250.18 OWF53497.1 - 1.3e-38 131.1 0.1 2.9e-38 130.0 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Methyltransf_22 PF13383.6 OWF53498.1 - 4.3e-20 72.4 0.5 4.7e-20 72.2 0.5 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF53498.1 - 1.7e-05 24.9 0.4 0.0011 19.1 0.3 2.1 1 1 1 2 2 2 2 Methyltransferase FkbM domain Kelch_1 PF01344.25 OWF53498.1 - 0.1 12.2 0.0 0.63 9.7 0.0 2.3 2 0 0 2 2 2 0 Kelch motif DnaJ_C PF01556.18 OWF53499.1 - 3.2e-42 144.1 0.1 4.6e-42 143.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OWF53499.1 - 2.7e-25 88.2 0.7 4.5e-25 87.5 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OWF53499.1 - 2.3e-17 63.1 20.1 3.9e-17 62.4 20.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OWF53499.1 - 3.2e-05 23.8 11.5 0.02 14.8 2.3 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OWF53499.1 - 0.016 15.2 8.3 1.1 9.3 2.0 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 OWF53499.1 - 0.034 14.1 5.2 0.57 10.2 0.4 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 OWF53499.1 - 0.63 10.1 9.8 8.1 6.5 9.8 2.3 1 1 0 1 1 1 0 zinc-ribbons TackOD1 PF18551.1 OWF53499.1 - 2.4 7.8 9.3 1.8 8.2 1.6 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Peptidase_M24 PF00557.24 OWF53500.1 - 2.8e-44 151.3 0.3 7e-44 150.0 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 OWF53500.1 - 5e-26 90.9 0.0 1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NUDIX PF00293.28 OWF53501.1 - 0.00074 19.6 0.0 0.75 9.8 0.0 3.1 2 1 1 3 3 3 2 NUDIX domain zf-C3HC4 PF00097.25 OWF53502.1 - 6.3e-08 32.4 14.8 6.3e-08 32.4 14.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF53502.1 - 6.5e-08 32.3 15.2 6.5e-08 32.3 15.2 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF53502.1 - 8.6e-08 32.4 15.1 8.6e-08 32.4 15.1 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF53502.1 - 2.8e-06 27.1 17.1 2.8e-06 27.1 17.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF53502.1 - 3e-06 27.2 11.8 3e-06 27.2 11.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF53502.1 - 5.1e-05 23.4 13.0 5.1e-05 23.4 13.0 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF53502.1 - 0.0035 17.3 18.1 0.0035 17.3 18.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF53502.1 - 0.021 14.7 15.6 0.062 13.2 15.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-3CxxC_2 PF17180.4 OWF53502.1 - 0.024 15.4 2.2 0.024 15.4 2.2 3.0 2 1 1 3 3 3 0 Zinc-binding domain zf-RING_6 PF14835.6 OWF53502.1 - 0.049 13.5 11.4 0.043 13.7 9.0 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OWF53502.1 - 0.07 12.9 12.7 0.35 10.7 12.7 2.3 1 0 0 1 1 1 0 RING-like zinc finger GAS PF13851.6 OWF53503.1 - 5.2e-81 270.8 25.5 5.2e-81 270.8 25.5 3.3 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 OWF53503.1 - 0.0011 19.3 1.0 0.0011 19.3 1.0 7.3 6 4 4 10 10 10 1 Csm1 N-terminal domain Baculo_PEP_C PF04513.12 OWF53503.1 - 0.17 11.9 12.9 0.73 9.9 0.7 3.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Metal_resist PF13801.6 OWF53503.1 - 0.32 11.2 0.0 0.32 11.2 0.0 4.9 3 2 2 5 5 5 0 Heavy-metal resistance DUF3584 PF12128.8 OWF53503.1 - 0.79 7.2 51.4 1.1 6.7 51.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MLTR_LBD PF17765.1 OWF53503.1 - 1.1 9.4 4.9 0.69 10.0 0.4 2.6 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain Spc7 PF08317.11 OWF53503.1 - 3.8 6.3 62.7 0.05 12.5 20.7 3.9 1 1 2 4 4 4 0 Spc7 kinetochore protein DUF948 PF06103.11 OWF53503.1 - 7.5 6.9 12.8 5.9 7.2 0.1 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 OWF53503.1 - 8.4 5.8 64.6 0.3 10.5 20.3 4.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 FERM_N PF09379.10 OWF53504.1 - 3.6e-15 55.6 0.0 8.3e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain zf-C3HC4_3 PF13920.6 OWF53504.1 - 3e-13 49.4 14.2 8.3e-13 48.0 14.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.10 OWF53504.1 - 1e-06 29.0 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 OWF53504.1 - 1.2e-06 29.0 2.2 1.5e-06 28.6 0.2 2.1 2 0 0 2 2 2 1 FERM central domain Prok-RING_4 PF14447.6 OWF53504.1 - 3e-06 27.0 15.0 9.3e-06 25.4 15.0 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TerY_C PF15616.6 OWF53504.1 - 0.0054 16.8 7.7 0.021 14.9 7.5 2.0 2 0 0 2 2 2 1 TerY-C metal binding domain TUG-UBL1 PF11470.8 OWF53504.1 - 0.059 13.6 0.0 0.82 9.9 0.0 2.4 2 0 0 2 2 2 0 TUG ubiquitin-like domain zf-RING_2 PF13639.6 OWF53504.1 - 0.18 12.2 21.6 0.087 13.2 16.2 2.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 OWF53504.1 - 0.93 9.5 18.0 0.42 10.6 15.1 2.0 2 0 0 2 2 2 0 zinc-RING finger domain DAO PF01266.24 OWF53505.1 - 5.7e-56 190.6 0.4 8.2e-56 190.1 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.21 OWF53505.1 - 1.8e-42 145.5 0.0 2.6e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain FAO_M PF16350.5 OWF53505.1 - 1.8e-09 37.8 0.0 3.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 OWF53505.1 - 2.6e-07 30.5 0.0 7.6e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Trp_halogenase PF04820.14 OWF53505.1 - 4.8e-06 25.7 1.8 0.00016 20.7 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 OWF53505.1 - 0.00021 21.8 1.5 0.63 10.6 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF53505.1 - 0.0012 19.0 0.7 0.0034 17.6 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OWF53505.1 - 0.0014 17.9 0.1 0.59 9.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 OWF53505.1 - 0.0018 17.7 0.3 1.6 8.0 0.1 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 OWF53505.1 - 0.0034 16.5 3.5 0.015 14.4 3.5 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OWF53505.1 - 0.0047 16.2 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF53505.1 - 0.064 12.5 1.3 0.44 9.7 0.5 2.4 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 OWF53505.1 - 0.19 11.0 2.1 6.1 6.0 0.2 2.8 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 OWF53506.1 - 5.2e-54 184.2 0.2 8.1e-54 183.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.21 OWF53506.1 - 2.8e-52 177.6 0.0 4.3e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain FAO_M PF16350.5 OWF53506.1 - 4.8e-09 36.4 0.0 9.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 OWF53506.1 - 3.4e-06 26.5 0.1 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OWF53506.1 - 4.3e-06 25.8 0.4 0.0002 20.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GCV_T_C PF08669.11 OWF53506.1 - 6.8e-06 25.9 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.24 OWF53506.1 - 2.9e-05 23.3 0.9 0.0028 16.8 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OWF53506.1 - 3.4e-05 23.3 0.1 0.044 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 OWF53506.1 - 0.0006 19.3 0.2 0.24 10.7 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase Thi4 PF01946.17 OWF53506.1 - 0.0011 18.3 0.9 0.22 10.7 0.2 2.5 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 OWF53506.1 - 0.0056 16.9 0.5 0.015 15.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OWF53506.1 - 0.0092 16.5 2.1 1 10.0 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OWF53506.1 - 0.013 14.8 0.4 3.4 6.8 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 OWF53506.1 - 0.024 14.0 0.7 0.15 11.4 0.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 OWF53506.1 - 0.16 12.2 0.1 0.41 10.9 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain DUF3325 PF11804.8 OWF53506.1 - 0.17 12.0 0.6 0.34 11.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) GCV_T PF01571.21 OWF53507.1 - 5.7e-69 232.3 0.0 8.1e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 OWF53507.1 - 6.4e-61 206.9 0.1 1e-60 206.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 OWF53507.1 - 9.5e-17 61.1 0.1 2e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 OWF53507.1 - 1.3e-10 41.1 0.0 3.7e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.24 OWF53507.1 - 2.3e-06 27.0 0.2 3.4e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OWF53507.1 - 1.2e-05 24.7 0.1 0.025 13.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OWF53507.1 - 0.00039 20.9 0.8 0.62 10.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF53507.1 - 0.0034 16.7 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 OWF53507.1 - 0.0034 17.5 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family GMC_oxred_N PF00732.19 OWF53507.1 - 0.0043 16.5 0.1 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OWF53507.1 - 0.01 16.0 0.3 0.028 14.7 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OWF53507.1 - 0.025 13.5 1.1 0.13 11.1 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 OWF53507.1 - 0.056 13.7 0.5 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 OWF53507.1 - 0.13 11.4 1.0 0.48 9.6 0.4 1.9 2 0 0 2 2 2 0 Thi4 family BOP1NT PF08145.12 OWF53508.1 - 7.6e-108 360.4 15.8 1.2e-107 359.7 15.8 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OWF53508.1 - 1.1e-27 95.7 7.7 1.3e-10 41.7 0.2 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF53508.1 - 1.4e-07 31.7 0.2 0.00035 20.8 0.1 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Rieske PF00355.26 OWF53508.1 - 0.15 12.0 0.0 0.59 10.1 0.0 2.0 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain SDA1 PF05285.12 OWF53508.1 - 0.55 9.6 17.3 1.1 8.6 17.3 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OWF53508.1 - 6.8 4.9 14.9 11 4.1 14.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Inositol_P PF00459.25 OWF53509.1 - 1.1e-75 254.7 1.1 1.3e-75 254.5 1.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF2102 PF09875.9 OWF53509.1 - 0.034 13.9 0.2 0.069 12.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Adhesin_P1_N PF18652.1 OWF53509.1 - 0.047 13.7 0.4 0.092 12.8 0.4 1.5 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain Phage_Cox PF10743.9 OWF53509.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Regulatory phage protein cox IMPDH PF00478.25 OWF53510.1 - 1.7e-80 270.6 3.6 2.2e-80 270.2 3.6 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OWF53510.1 - 0.00015 21.0 1.8 0.00029 20.0 1.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase QRPTase_C PF01729.19 OWF53510.1 - 0.069 12.9 0.0 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Aldolase PF01081.19 OWF53510.1 - 0.071 12.5 0.3 0.52 9.7 0.0 2.1 1 1 0 2 2 2 0 KDPG and KHG aldolase NBD_C PF17042.5 OWF53510.1 - 0.088 13.3 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 Nucleotide-binding C-terminal domain Aminotran_5 PF00266.19 OWF53511.1 - 2.7e-90 303.0 0.0 3.2e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OWF53511.1 - 7.7e-09 35.2 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OWF53511.1 - 2.9e-05 23.6 0.2 4.5e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 OWF53511.1 - 0.00042 19.1 0.0 0.00069 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF724 PF05266.14 OWF53511.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PP2C PF00481.21 OWF53512.1 - 9.3e-39 133.6 0.0 1.3e-35 123.3 0.0 2.4 1 1 0 2 2 2 2 Protein phosphatase 2C Ank_2 PF12796.7 OWF53512.1 - 5.6e-34 116.6 6.8 1.9e-13 50.8 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53512.1 - 4.7e-24 84.4 4.0 1.4e-06 28.7 0.0 5.2 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF53512.1 - 5.8e-20 69.3 8.7 0.0034 17.7 0.1 8.4 8 0 0 8 8 7 5 Ankyrin repeat Ank_5 PF13857.6 OWF53512.1 - 2.2e-18 66.1 8.0 0.00017 21.8 0.0 8.6 2 1 7 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF53512.1 - 1.2e-13 50.9 2.3 0.099 13.1 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat SOCS_box PF07525.16 OWF53512.1 - 2.8e-09 37.2 0.7 6.7e-09 36.0 0.7 1.7 1 0 0 1 1 1 1 SOCS box Shigella_OspC PF06128.11 OWF53512.1 - 0.0007 19.4 1.9 0.048 13.4 1.4 3.0 2 1 1 3 3 3 1 Shigella flexneri OspC protein DUF3447 PF11929.8 OWF53512.1 - 0.012 15.5 1.2 1.2 9.1 0.3 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Nudix_hydro PF18290.1 OWF53512.1 - 0.12 12.4 0.0 38 4.4 0.0 3.2 2 1 1 3 3 3 0 Nudix hydrolase domain UPF0180 PF03698.13 OWF53512.1 - 0.15 12.2 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Guanylate_cyc PF00211.20 OWF53513.1 - 2.8e-70 235.7 0.1 7.2e-70 234.3 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OWF53513.1 - 5.1e-36 124.2 2.4 6.8e-34 117.2 2.4 2.4 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 OWF53513.1 - 1.5e-35 122.5 0.1 2.9e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 Haem-NO-binding adh_short PF00106.25 OWF53514.1 - 1e-33 116.5 0.4 1.4e-33 116.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF53514.1 - 7.7e-28 97.6 0.2 1.2e-27 97.0 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 OWF53514.1 - 0.09 12.1 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 OWF53514.1 - 0.11 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 KR domain Cys_Met_Meta_PP PF01053.20 OWF53515.1 - 2.5e-130 434.4 0.0 2.8e-130 434.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OWF53515.1 - 0.00073 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 OWF53515.1 - 0.0044 15.6 0.0 0.0079 14.8 0.0 1.3 1 1 0 1 1 1 1 Methionine gamma-lyase Ndr PF03096.14 OWF53516.1 - 7.6e-95 316.8 0.0 2.4e-94 315.2 0.0 1.7 1 1 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 OWF53516.1 - 1.5e-06 28.1 0.1 3.4e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF53516.1 - 3.1e-05 23.3 0.0 4.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF53516.1 - 3.2e-05 24.7 0.0 4.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pept_S41_N PF18294.1 OWF53516.1 - 0.3 11.1 3.4 0.73 9.9 3.4 1.6 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain TTC5_OB PF16669.5 OWF53517.1 - 9.3e-37 125.2 0.0 1.7e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_2 PF07719.17 OWF53517.1 - 1.9e-11 43.2 2.2 0.0041 17.1 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF53517.1 - 1.8e-08 33.9 10.0 0.00038 20.2 0.2 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF53517.1 - 5.8e-08 32.3 1.9 0.00098 18.8 0.0 4.5 3 1 1 4 4 4 1 TPR repeat TPR_17 PF13431.6 OWF53517.1 - 1.2e-05 25.3 0.2 0.25 11.8 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF53517.1 - 1.6e-05 25.3 0.1 0.0076 16.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF53517.1 - 0.00032 21.3 0.0 0.35 11.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF53517.1 - 0.0067 16.6 13.2 0.07 13.4 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat EF-G-binding_N PF07299.11 OWF53517.1 - 0.013 16.0 1.5 0.04 14.5 0.1 2.3 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal TPR_12 PF13424.6 OWF53517.1 - 0.031 14.6 1.0 6.6 7.1 0.0 3.3 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF53517.1 - 0.062 13.5 0.0 19 5.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2813 PF11398.8 OWF53517.1 - 0.09 12.0 1.2 0.16 11.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) TPR_14 PF13428.6 OWF53517.1 - 0.091 13.6 0.0 4.9 8.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RecG_N PF17190.4 OWF53517.1 - 0.2 12.4 7.0 2.7 8.8 0.0 3.3 3 1 0 3 3 3 0 RecG N-terminal helical domain SieB PF14163.6 OWF53517.1 - 3.8 7.0 6.3 2.1e+02 1.3 4.6 3.0 2 1 0 2 2 2 0 Super-infection exclusion protein B MatE PF01554.18 OWF53518.1 - 3.5e-50 169.8 31.7 1.2e-25 90.0 13.9 2.3 2 0 0 2 2 2 2 MatE Hormone_recep PF00104.30 OWF53519.1 - 2.2e-39 135.2 0.1 1e-38 133.0 0.0 1.9 1 1 1 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 OWF53519.1 - 1.3e-29 102.4 18.9 2.1e-29 101.7 18.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF1110 PF06533.12 OWF53519.1 - 0.0078 16.2 0.4 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1110) WD40 PF00400.32 OWF53520.1 - 2.4e-25 88.3 18.2 3.3e-05 24.6 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 OWF53520.1 - 4.4e-08 32.1 0.1 0.0018 16.9 0.0 3.2 3 0 0 3 3 3 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 OWF53520.1 - 8.2e-08 32.4 0.1 2 8.8 0.0 5.4 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OWF53520.1 - 0.00027 20.1 0.1 0.1 11.7 0.1 2.4 2 0 0 2 2 2 2 Coatomer WD associated region Ge1_WD40 PF16529.5 OWF53520.1 - 0.00035 19.6 0.2 0.17 10.8 0.2 3.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 OWF53520.1 - 0.0022 17.8 6.3 0.67 10.0 0.2 4.1 4 0 0 4 4 4 1 PQQ enzyme repeat PD40 PF07676.12 OWF53520.1 - 0.011 15.6 0.4 0.056 13.4 0.2 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 OWF53520.1 - 0.042 12.2 0.1 5 5.3 0.0 3.1 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz NAGPA PF09992.9 OWF53521.1 - 3e-36 125.2 0.4 4.4e-36 124.6 0.4 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase Vinculin PF01044.19 OWF53522.1 - 2.1e-115 387.1 42.5 9.2e-40 136.7 0.6 5.2 5 0 0 5 5 5 5 Vinculin family Goodbye PF17109.5 OWF53522.1 - 0.087 13.3 0.1 7.1 7.1 0.0 3.5 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain EH_Signature PF15611.6 OWF53522.1 - 0.15 11.4 9.9 0.31 10.4 0.6 3.5 3 1 0 3 3 3 0 EH_Signature domain SNARE PF05739.19 OWF53523.1 - 7.9e-21 73.8 3.4 7.9e-21 73.8 3.4 2.2 3 0 0 3 3 2 1 SNARE domain Syntaxin PF00804.25 OWF53523.1 - 1.3e-07 31.5 15.4 1.3e-07 31.5 15.4 1.9 2 0 0 2 2 2 1 Syntaxin DUF5345 PF17280.2 OWF53523.1 - 0.0032 17.4 0.2 0.012 15.6 0.2 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5345) Abi_C PF14355.6 OWF53523.1 - 0.012 15.7 0.9 2.5 8.3 0.2 2.7 2 0 0 2 2 2 0 Abortive infection C-terminus MCPsignal PF00015.21 OWF53523.1 - 0.013 15.3 0.5 0.013 15.3 0.5 2.9 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.11 OWF53523.1 - 0.015 13.3 15.4 0.027 12.4 15.4 1.4 1 1 0 1 1 1 0 Prominin TRP PF06011.12 OWF53523.1 - 0.019 13.7 0.1 0.022 13.5 0.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel T3SS_needle_E PF08988.10 OWF53523.1 - 0.053 13.7 0.1 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF2207 PF09972.9 OWF53523.1 - 0.087 11.6 2.1 0.11 11.3 0.7 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2116 PF09889.9 OWF53523.1 - 0.1 12.6 3.5 0.25 11.3 3.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ETRAMP PF09716.10 OWF53523.1 - 0.33 11.0 3.4 0.92 9.6 3.4 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3087 PF11286.8 OWF53523.1 - 0.77 9.2 7.2 0.59 9.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) FlaC_arch PF05377.11 OWF53523.1 - 0.82 10.1 8.4 0.87 10.0 1.3 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 OWF53523.1 - 2.4 8.2 8.3 1.8 8.6 0.8 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 OWF53523.1 - 2.7 7.2 15.8 3.9 6.6 1.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein HMG_box PF00505.19 OWF53524.1 - 7e-18 64.8 0.9 1.6e-17 63.7 0.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF53524.1 - 3.1e-06 27.7 0.5 3.1e-06 27.7 0.5 1.9 2 0 0 2 2 2 1 HMG-box domain DUF4604 PF15377.6 OWF53525.1 - 2.8 8.3 29.3 3.5 8.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Tmemb_170 PF10190.9 OWF53526.1 - 4.4e-39 133.1 10.5 5.2e-39 132.9 10.5 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 LptF_LptG PF03739.14 OWF53526.1 - 0.0012 17.8 0.3 0.0012 17.8 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Gal_Lectin PF02140.18 OWF53527.1 - 1.8e-16 60.3 1.1 1.8e-16 60.3 1.1 1.9 1 1 0 2 2 2 1 Galactose binding lectin domain Methyltransf_FA PF12248.8 OWF53528.1 - 9.8e-23 80.4 0.3 1.4e-22 80.0 0.3 1.2 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase SH3_16 PF18348.1 OWF53528.1 - 0.031 14.1 1.0 0.46 10.3 0.0 2.5 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain Collagen PF01391.18 OWF53529.1 - 1.2e-26 92.3 80.0 2.8e-10 39.8 18.8 3.5 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) C1q PF00386.21 OWF53529.1 - 5.5e-15 55.7 0.2 8.4e-15 55.1 0.2 1.3 1 0 0 1 1 1 1 C1q domain HOOK PF05622.12 OWF53529.1 - 0.0036 15.5 0.3 0.0046 15.2 0.3 1.0 1 0 0 1 1 1 1 HOOK protein DUF3450 PF11932.8 OWF53529.1 - 0.0083 15.5 0.3 0.012 14.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF713 PF05218.14 OWF53529.1 - 0.033 13.9 0.2 0.049 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) BclA_C PF18573.1 OWF53529.1 - 0.093 12.6 1.6 0.15 12.0 1.6 1.2 1 0 0 1 1 1 0 BclA C-terminal domain HALZ PF02183.18 OWF53529.1 - 1.3 9.3 3.0 0.9 9.8 0.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper CD225 PF04505.12 OWF53530.1 - 1e-18 67.2 0.6 1.5e-18 66.7 0.6 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein NADH-u_ox-rdase PF10785.9 OWF53530.1 - 0.0089 16.7 0.0 0.016 15.9 0.0 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Fibrinogen_BP PF08017.11 OWF53531.1 - 3.1e-13 49.0 29.7 1.4e-08 33.6 15.5 2.1 2 0 0 2 2 2 2 Fibrinogen binding protein Cornifin PF02389.15 OWF53531.1 - 0.014 15.6 14.1 0.096 12.9 5.9 2.2 1 1 1 2 2 2 0 Cornifin (SPRR) family MotCF PF09158.10 OWF53531.1 - 0.37 10.9 11.9 0.92 9.6 1.3 3.3 2 1 1 3 3 3 0 Bacteriophage T4 MotA, C-terminal Cue1_U7BR PF18499.1 OWF53531.1 - 0.65 10.1 9.5 14 5.8 0.1 5.2 2 2 2 5 5 5 0 Ubc7p-binding region of Cue1 AA_permease_2 PF13520.6 OWF53532.1 - 3.7e-63 213.8 52.9 4.6e-63 213.5 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OWF53532.1 - 1.4e-32 112.9 45.9 2e-32 112.4 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease WSN PF02206.18 OWF53534.1 - 0.12 12.3 0.1 3.3 7.7 0.0 2.9 2 2 2 4 4 4 0 Domain of unknown function Cyt_b-c1_8 PF10890.8 OWF53534.1 - 0.34 11.3 8.3 1.6e+02 2.8 0.1 6.5 1 1 7 8 8 8 0 Cytochrome b-c1 complex subunit 8 Armet PF10208.9 OWF53534.1 - 0.61 10.0 5.5 7.8 6.4 0.3 3.2 1 1 2 3 3 3 0 Degradation arginine-rich protein for mis-folding Kv2channel PF03521.14 OWF53535.1 - 0.015 14.7 1.1 1.2e+02 1.9 0.0 5.3 2 2 3 6 6 6 0 Kv2 voltage-gated K+ channel SAM_2 PF07647.17 OWF53537.1 - 6e-07 29.5 0.1 1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.6 OWF53537.1 - 3.7e-06 27.0 9.7 1.1e-05 25.5 9.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OWF53537.1 - 3.8e-06 26.7 10.8 1e-05 25.3 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF53537.1 - 3.9e-06 27.1 12.1 8.7e-06 26.0 12.1 1.6 1 0 0 1 1 1 1 Ring finger domain SAM_1 PF00536.30 OWF53537.1 - 5.1e-06 26.8 0.2 1e-05 25.9 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-RING_UBOX PF13445.6 OWF53537.1 - 8.4e-06 25.7 12.0 1.9e-05 24.6 12.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF53537.1 - 7.6e-05 22.5 11.9 0.00017 21.4 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_Ste50p PF09235.10 OWF53537.1 - 0.00011 22.4 0.1 0.00053 20.2 0.1 2.1 2 0 0 2 2 2 1 Ste50p, sterile alpha motif zf-C3HC4_3 PF13920.6 OWF53537.1 - 0.0003 20.6 7.7 0.0003 20.6 7.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF53537.1 - 0.0046 16.9 13.0 0.0091 15.9 13.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain SAM_PNT PF02198.16 OWF53537.1 - 0.01 15.7 0.2 0.14 12.1 0.1 2.6 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain zf-rbx1 PF12678.7 OWF53537.1 - 0.025 14.9 8.1 0.064 13.6 8.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF53537.1 - 0.04 14.1 6.6 0.09 12.9 6.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 OWF53537.1 - 0.17 11.8 3.9 0.37 10.7 3.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OWF53537.1 - 0.26 11.4 7.3 0.1 12.7 4.3 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1244 PF06844.11 OWF53537.1 - 1.2 9.4 4.1 3.8 7.7 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) Prok-RING_4 PF14447.6 OWF53537.1 - 2 8.3 8.6 4.6 7.2 8.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ComP_DUS PF16732.5 OWF53540.1 - 0.0082 17.0 5.1 1.2e+02 3.6 4.6 6.1 3 1 2 5 5 5 0 Type IV minor pilin ComP, DNA uptake sequence receptor Gln_amidase PF15644.6 OWF53540.1 - 0.079 14.0 1.8 1.9e+02 3.1 0.0 5.9 2 1 2 4 4 4 0 Papain fold toxin 1, glutamine deamidase SCO1-SenC PF02630.14 OWF53540.1 - 0.16 11.9 2.7 4.6 7.2 0.1 3.9 3 0 0 3 3 3 0 SCO1/SenC DUF2070 PF09843.9 OWF53540.1 - 0.22 9.8 2.1 0.3 9.3 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) zf-H2C2_2 PF13465.6 OWF53541.1 - 8e-23 79.8 55.9 1.8e-06 28.1 0.3 10.1 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF53541.1 - 3.4e-16 58.5 69.5 0.04 14.8 0.7 11.5 11 0 0 11 11 11 9 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF53541.1 - 3e-13 49.4 74.6 0.00082 19.7 0.9 11.0 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF53541.1 - 3.5e-10 39.4 43.5 0.00074 19.2 0.1 8.3 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 OWF53541.1 - 0.00011 22.4 43.4 0.002 18.4 0.7 6.8 5 2 1 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 OWF53541.1 - 0.015 15.6 1.0 0.015 15.6 1.0 3.9 4 0 0 4 4 4 0 zinc-finger-containing domain zf-C2H2_8 PF15909.5 OWF53541.1 - 0.018 15.3 1.3 0.018 15.3 1.3 4.7 2 1 3 5 5 5 0 C2H2-type zinc ribbon GAGA PF09237.11 OWF53541.1 - 0.49 10.2 5.5 3.9 7.4 0.2 3.3 2 1 0 3 3 3 0 GAGA factor Zn-ribbon_8 PF09723.10 OWF53541.1 - 2.2 8.5 29.0 0.92 9.7 0.2 6.2 5 1 1 6 6 6 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 OWF53541.1 - 2.3 8.1 12.2 10 6.0 0.2 5.1 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) BLOC1_2 PF10046.9 OWF53542.1 - 0.0061 16.8 2.7 0.016 15.5 0.1 2.5 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CREPT PF16566.5 OWF53542.1 - 0.0079 16.4 3.2 0.014 15.6 0.1 2.2 1 1 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour TMF_TATA_bd PF12325.8 OWF53542.1 - 0.026 14.7 6.9 2.3 8.5 2.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cob_adeno_trans PF01923.18 OWF53542.1 - 0.031 14.4 0.3 0.061 13.5 0.1 1.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase ALIX_LYPXL_bnd PF13949.6 OWF53542.1 - 0.071 12.4 4.6 0.15 11.3 0.9 2.1 1 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV HSBP1 PF06825.12 OWF53542.1 - 0.13 12.1 2.4 8.1 6.4 0.0 2.8 2 1 0 2 2 2 0 Heat shock factor binding protein 1 CENP-F_leu_zip PF10473.9 OWF53542.1 - 0.64 10.0 10.4 8.7 6.4 5.4 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PCRF PF03462.18 OWF53542.1 - 5.5 6.8 7.2 0.96 9.3 0.2 2.1 1 1 1 2 2 2 0 PCRF domain Pyr_redox_3 PF13738.6 OWF53543.1 - 1.5e-12 47.4 0.0 1.4e-11 44.2 0.0 2.4 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF53543.1 - 9.5e-08 31.6 0.0 2.1e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF53543.1 - 1.1e-05 24.8 0.0 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_GDSL_2 PF13472.6 OWF53544.1 - 3.2e-09 37.5 0.0 3.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF53544.1 - 1.1e-08 35.3 0.0 1.3e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipocalin_2 PF08212.12 OWF53545.1 - 5.4e-09 36.1 0.0 7.2e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF53545.1 - 0.00024 21.3 0.0 0.00037 20.7 0.0 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Abhydrolase_1 PF00561.20 OWF53546.1 - 1.5e-18 67.4 0.0 1.1e-12 48.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF53546.1 - 1.1e-11 45.7 0.0 1.5e-11 45.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OWF53546.1 - 9.8e-11 41.4 0.0 2.7e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 OWF53546.1 - 0.0061 16.5 0.0 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OWF53546.1 - 0.0078 15.9 0.1 0.029 14.0 0.1 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 OWF53546.1 - 0.032 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF1057 PF06342.12 OWF53546.1 - 0.084 11.9 0.0 2.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) NMD3 PF04981.13 OWF53546.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 NMD3 family Hydantoinase_B PF02538.14 OWF53547.1 - 1.5e-218 726.4 1.8 2.1e-218 726.0 1.8 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OWF53547.1 - 8.9e-108 360.0 0.4 1.8e-107 358.9 0.4 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OWF53547.1 - 2e-61 206.8 0.1 1.8e-59 200.4 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region CUB PF00431.20 OWF53548.1 - 1.3e-38 131.7 0.6 4.8e-27 94.5 0.1 2.8 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 OWF53548.1 - 7.8e-05 22.8 10.9 0.00017 21.7 10.9 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Glycophorin_A PF01102.18 OWF53548.1 - 0.0044 17.3 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A Shisa PF13908.6 OWF53548.1 - 0.029 14.6 1.6 0.049 13.9 0.7 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 OWF53548.1 - 0.076 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LRR19-TM PF15176.6 OWF53548.1 - 0.094 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF1179 PF06678.11 OWF53548.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) OSTbeta PF15048.6 OWF53548.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein TM231 PF10149.9 OWF53549.1 - 2.8e-109 365.1 4.4 3.1e-109 364.9 4.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 CBM_21 PF03370.13 OWF53550.1 - 1.1e-26 93.2 0.2 2.5e-26 92.1 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OWF53550.1 - 5.6e-12 46.1 0.1 1.5e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF2452 PF10504.9 OWF53550.1 - 0.0085 15.6 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2452) tRNA-synt_2d PF01409.20 OWF53551.1 - 2.2e-47 161.6 0.3 5.5e-29 101.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OWF53551.1 - 1e-18 67.5 0.0 2.4e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Glyco_transf_43 PF03360.16 OWF53552.1 - 5.4e-67 225.6 0.0 6.5e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 ResB PF05140.14 OWF53552.1 - 0.33 9.6 1.1 0.49 9.1 1.1 1.2 1 0 0 1 1 1 0 ResB-like family SNF PF00209.18 OWF53554.1 - 2.4e-131 439.0 29.8 3.1e-131 438.6 29.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF53555.1 - 9.5e-183 608.6 35.1 5.1e-182 606.2 35.1 1.8 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF5054 PF16477.5 OWF53556.1 - 8.2e-33 114.4 0.0 2.4e-32 112.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5054) Pneumo_M2 PF07380.11 OWF53556.1 - 0.0099 16.1 0.4 1.5 9.1 0.1 2.7 2 0 0 2 2 2 2 Pneumovirus M2 protein DUF2877 PF11392.8 OWF53557.1 - 0.19 12.4 0.5 2.8 8.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2877) TNFR_c6 PF00020.18 OWF53559.1 - 3.6e-13 49.7 36.4 0.00013 22.3 4.6 4.5 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region RAP-1 PF03085.15 OWF53559.1 - 3.2 7.4 7.9 6.5 6.4 7.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_20 PF00728.22 OWF53560.1 - 7.5e-79 265.7 0.2 1.1e-78 265.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OWF53560.1 - 4.9e-17 62.9 0.0 9.8e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OWF53560.1 - 2.2e-05 25.2 0.0 4.1e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sigma70_r2 PF04542.14 OWF53560.1 - 0.065 13.0 0.0 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-70 region 2 LRR_6 PF13516.6 OWF53562.1 - 6.9e-16 56.9 47.3 0.1 12.7 0.1 14.7 15 0 0 15 15 15 6 Leucine Rich repeat LRR_4 PF12799.7 OWF53562.1 - 3.1e-14 52.8 37.1 0.011 16.1 0.0 10.3 5 3 4 11 11 11 6 Leucine Rich repeats (2 copies) F-box PF00646.33 OWF53562.1 - 0.00014 21.6 0.3 0.022 14.6 0.1 3.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OWF53562.1 - 0.00024 20.9 0.1 0.0016 18.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 OWF53562.1 - 0.15 11.7 0.3 0.77 9.4 0.2 2.3 2 0 0 2 2 2 0 F-box LRR_1 PF00560.33 OWF53562.1 - 0.19 12.4 40.2 24 6.0 0.1 12.2 12 2 0 12 12 12 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 OWF53562.1 - 2.1 8.6 24.1 2.3 8.5 0.0 6.9 5 2 2 7 7 7 0 Ste50p, sterile alpha motif dNK PF01712.19 OWF53563.1 - 5.6e-38 130.8 0.2 8.1e-38 130.3 0.2 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 OWF53563.1 - 4.4e-08 33.7 0.1 8.9e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF53563.1 - 0.00042 20.5 0.1 0.011 15.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 OWF53563.1 - 0.01 15.9 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE E1_DerP2_DerF2 PF02221.15 OWF53564.1 - 2.4e-05 24.7 0.4 3.6e-05 24.2 0.4 1.2 1 0 0 1 1 1 1 ML domain Homeodomain PF00046.29 OWF53565.1 - 3.5e-21 74.8 1.9 3.5e-21 74.8 1.9 1.8 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 OWF53566.1 - 6.2e-22 77.2 2.0 1.1e-21 76.4 2.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF53566.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain LRR_8 PF13855.6 OWF53567.1 - 3.7e-23 81.1 35.7 9.6e-10 38.1 10.9 4.1 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OWF53567.1 - 5.6e-22 77.5 31.9 7.9e-06 26.1 2.7 6.2 2 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF53567.1 - 5.5e-06 26.0 10.4 7.3e-05 22.3 6.3 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OWF53567.1 - 6.7e-05 22.9 29.6 4.1 8.3 0.3 9.1 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 OWF53567.1 - 0.86 9.8 25.2 16 5.9 0.4 6.9 7 0 0 7 7 7 0 Leucine Rich repeat HA2 PF04408.23 OWF53568.1 - 6.1e-21 74.7 0.0 6.1e-21 74.7 0.0 4.5 5 0 0 5 5 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OWF53568.1 - 8.2e-15 54.9 0.0 1.8e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OWF53568.1 - 9.4e-12 45.3 0.0 2.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF53568.1 - 8.3e-07 28.9 0.6 2.2e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF53568.1 - 7.4e-06 26.3 0.1 3e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF53568.1 - 0.0007 20.0 0.1 0.0021 18.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 OWF53568.1 - 0.0021 17.2 0.0 0.0048 16.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 OWF53568.1 - 0.0097 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OWF53568.1 - 0.015 15.4 1.1 1.2 9.2 0.2 3.1 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 OWF53568.1 - 0.016 15.2 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 OWF53568.1 - 0.049 13.6 2.5 7.2 6.6 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 OWF53568.1 - 0.057 13.2 0.1 3 7.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 OWF53568.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 OWF53568.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OWF53568.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain MIB_HERC2 PF06701.13 OWF53569.1 - 8.5e-07 29.1 81.0 70 3.8 0.1 21.2 1 1 20 21 21 21 0 Mib_herc2 GP40 PF11025.8 OWF53569.1 - 3.2e-05 23.7 31.8 20 4.9 0.1 10.3 2 1 14 18 18 18 1 Glycoprotein GP40 of Cryptosporidium GlcNAc_2-epim PF07221.11 OWF53569.1 - 0.043 13.1 36.0 29 3.8 0.6 9.1 1 1 13 14 14 14 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) VWA PF00092.28 OWF53570.1 - 9e-77 257.3 8.9 9.6e-46 156.2 1.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OWF53570.1 - 3.9e-28 98.2 0.0 1.1e-16 61.4 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain ShK PF01549.24 OWF53570.1 - 0.0012 19.4 9.1 0.0012 19.4 9.1 8.4 10 0 0 10 10 10 3 ShK domain-like VWC PF00093.18 OWF53570.1 - 0.0049 17.2 291.8 0.022 15.1 15.2 13.8 14 0 0 14 14 14 11 von Willebrand factor type C domain VWC PF00093.18 OWF53571.1 - 1.4e-36 124.6 416.1 0.00029 21.1 7.8 19.6 19 0 0 19 19 19 19 von Willebrand factor type C domain SNF PF00209.18 OWF53572.1 - 8.4e-191 635.2 39.4 1.1e-190 634.8 39.4 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TIR PF01582.20 OWF53574.1 - 1.9e-21 76.6 0.2 4.2e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 TIR domain LRR_8 PF13855.6 OWF53574.1 - 2.4e-19 68.8 39.1 3.2e-06 26.8 0.4 7.7 3 3 7 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 OWF53574.1 - 7.8e-13 48.4 39.1 0.0019 18.6 5.8 9.0 6 2 4 10 10 10 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 OWF53574.1 - 2.6e-12 47.4 0.0 5.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 TIR domain Glycophorin_A PF01102.18 OWF53574.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A LRR_9 PF14580.6 OWF53574.1 - 0.071 12.6 19.9 0.5 9.9 0.6 4.3 2 2 1 4 4 4 0 Leucine-rich repeat TPKR_C2 PF16920.5 OWF53574.1 - 0.13 12.4 0.3 0.59 10.3 0.3 2.2 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.33 OWF53574.1 - 1.5 9.7 0.0 1.5 9.7 0.0 8.3 10 2 0 10 10 10 0 Leucine Rich Repeat LRRNT PF01462.18 OWF53574.1 - 2.4 7.9 6.2 1.7 8.3 2.8 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain TIR PF01582.20 OWF53575.1 - 2.4e-23 82.8 0.2 3e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 TIR domain LRR_8 PF13855.6 OWF53575.1 - 1.9e-18 66.0 35.5 8e-06 25.5 6.2 6.4 5 1 1 6 6 6 5 Leucine rich repeat TIR_2 PF13676.6 OWF53575.1 - 3.8e-12 46.8 0.0 8.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF53575.1 - 2.2e-09 37.5 40.1 0.035 14.6 2.2 9.0 5 1 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF53575.1 - 0.00024 20.7 16.7 0.051 13.1 0.5 4.3 1 1 5 6 6 6 2 Leucine-rich repeat LRR_1 PF00560.33 OWF53575.1 - 0.0099 16.3 22.9 5.4 8.0 0.1 8.9 10 1 0 10 10 10 1 Leucine Rich Repeat Glycophorin_A PF01102.18 OWF53575.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A LRRNT PF01462.18 OWF53575.1 - 0.29 10.8 3.2 1.4 8.6 1.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 OWF53575.1 - 1 9.5 3.1 1.1 9.4 0.8 2.3 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 OWF53575.1 - 5.9 7.2 28.0 20 5.5 0.0 8.5 9 0 0 9 9 9 0 Leucine Rich repeat DUF2345 PF10106.9 OWF53576.1 - 4.9e-06 26.5 8.6 0.00064 19.6 2.1 3.0 2 1 1 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2345) Tetradecapep PF08187.11 OWF53576.1 - 0.0048 16.8 66.9 12 6.2 0.0 15.5 8 6 8 16 16 16 9 Myoactive tetradecapeptides family DUF4165 PF13752.6 OWF53576.1 - 0.61 10.1 5.2 14 5.7 0.1 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4165) Mtf2_C PF14061.6 OWF53576.1 - 1.3 9.3 9.8 99 3.2 0.0 6.4 4 3 3 7 7 7 0 Polycomb-like MTF2 factor 2 DUF4661 PF15576.6 OWF53576.1 - 9.8 6.0 6.6 5.6 6.8 0.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4661) Tetradecapep PF08187.11 OWF53577.1 - 7.7e-06 25.6 57.3 3.7 7.8 0.1 12.1 4 4 8 12 12 12 7 Myoactive tetradecapeptides family YebF PF13995.6 OWF53577.1 - 0.031 14.3 0.5 29 4.7 0.1 3.4 1 1 3 4 4 4 0 YebF-like protein BLIP PF07467.11 OWF53577.1 - 0.052 14.1 1.0 0.15 12.7 0.6 1.8 1 1 1 2 2 2 0 Beta-lactamase inhibitor (BLIP) Mtf2_C PF14061.6 OWF53577.1 - 0.15 12.3 9.7 87 3.4 0.2 6.1 3 2 2 5 5 5 0 Polycomb-like MTF2 factor 2 DUF4165 PF13752.6 OWF53577.1 - 0.23 11.5 5.5 15 5.6 0.2 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4165) zf-C3HC4_3 PF13920.6 OWF53578.1 - 1.9e-08 34.0 8.7 3.4e-08 33.2 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF53578.1 - 4.7e-05 23.2 6.7 0.0001 22.1 6.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OWF53578.1 - 0.0061 16.4 5.6 0.0061 16.4 5.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 OWF53578.1 - 0.028 14.8 5.5 0.057 13.8 5.5 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-TFIIIC PF12660.7 OWF53578.1 - 0.15 12.1 4.6 0.21 11.6 4.6 1.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex FSH1 PF03959.13 OWF53579.1 - 2.3e-57 194.1 0.0 2.9e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OWF53579.1 - 0.015 15.1 0.0 0.053 13.3 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase zf-B_box PF00643.24 OWF53580.1 - 1.6e-05 24.9 1.2 3.6e-05 23.8 1.2 1.6 1 0 0 1 1 1 1 B-box zinc finger RPW8 PF05659.11 OWF53580.1 - 0.0045 16.7 1.2 0.0045 16.7 1.2 2.4 2 1 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tropomyosin PF00261.20 OWF53580.1 - 0.16 11.3 26.5 0.023 14.1 17.7 2.3 2 1 0 2 2 2 0 Tropomyosin zf-UBR PF02207.20 OWF53580.1 - 0.21 11.8 2.5 0.5 10.6 2.5 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Shugoshin_N PF07558.11 OWF53580.1 - 0.21 11.5 4.8 6.2 6.8 0.0 3.4 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region MerR-DNA-bind PF09278.11 OWF53580.1 - 0.5 10.9 11.5 1.1 9.9 0.6 4.0 4 0 0 4 4 4 0 MerR, DNA binding ZYG-11_interact PF05884.12 OWF53580.1 - 0.83 9.0 3.3 0.51 9.7 0.1 1.9 2 0 0 2 2 2 0 Interactor of ZYG-11 APG6_N PF17675.1 OWF53580.1 - 0.95 10.0 26.7 0.37 11.3 9.9 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region PTR PF12789.7 OWF53580.1 - 1.2 9.2 4.7 2 8.5 0.1 3.3 3 1 1 4 4 4 0 Phage tail repeat like LPP PF04728.13 OWF53580.1 - 2.2 8.7 11.9 8.9 6.8 1.4 3.9 3 1 0 4 4 4 0 Lipoprotein leucine-zipper DUF572 PF04502.13 OWF53580.1 - 3.3 7.2 17.1 0.42 10.2 13.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Fib_alpha PF08702.10 OWF53580.1 - 3.5 7.8 24.9 4.8 7.4 5.5 3.3 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 OWF53580.1 - 4 6.8 23.5 0.23 10.9 1.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 OWF53580.1 - 4.5 6.1 29.7 0.9 8.4 3.5 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein Lectin_N PF03954.14 OWF53580.1 - 5.9 6.6 12.3 1.3 8.8 0.4 3.3 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.12 OWF53580.1 - 7.6 6.6 25.6 16 5.5 17.2 3.1 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Retrotrans_gag PF03732.17 OWF53581.1 - 0.00053 20.2 0.2 0.00082 19.6 0.1 1.4 1 1 0 1 1 1 1 Retrotransposon gag protein DUF2258 PF10015.9 OWF53581.1 - 0.079 13.1 0.2 0.17 12.0 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) zf-MYND PF01753.18 OWF53582.1 - 3.4e-20 71.8 38.4 6.3e-11 42.2 12.1 2.5 2 0 0 2 2 2 2 MYND finger MCM_bind PF09739.9 OWF53582.1 - 3.9 5.8 10.6 5.3 5.4 10.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor zf-C6H2 PF15801.5 OWF53582.1 - 3.9 7.9 32.2 3.8 7.9 15.1 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 OWF53583.1 - 3.4e-10 39.4 4.0 4.9e-10 38.9 4.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF53583.1 - 0.00054 18.9 0.9 0.013 14.4 0.5 2.6 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 OWF53583.1 - 0.00097 18.1 5.7 0.0014 17.6 5.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 OWF53583.1 - 0.033 12.7 4.2 0.051 12.1 3.9 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein REPA_OB_2 PF16900.5 OWF53583.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Replication protein A OB domain COPI_assoc PF08507.10 OWF53583.1 - 4 7.5 8.8 0.66 10.0 2.5 2.7 2 1 0 3 3 3 0 COPI associated protein MFS_1 PF07690.16 OWF53585.1 - 3.8e-34 118.2 11.6 1.1e-17 64.1 1.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF53585.1 - 0.0044 15.9 21.4 0.11 11.3 3.0 3.7 2 1 0 2 2 2 2 MFS_1 like family SpoVAB PF13782.6 OWF53585.1 - 0.63 10.4 14.3 0.75 10.1 2.0 3.2 3 1 1 4 4 4 0 Stage V sporulation protein AB ATG22 PF11700.8 OWF53585.1 - 6.6 5.2 21.0 1 7.9 5.7 3.4 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OWF53586.1 - 4.6e-24 85.0 18.0 1.2e-13 50.7 2.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 OWF53587.1 - 9e-40 137.3 4.8 1.1e-39 137.0 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OWF53587.1 - 1.3e-06 27.8 2.5 0.0014 17.7 0.0 3.1 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 OWF53587.1 - 0.0026 17.1 0.0 0.57 9.4 0.0 2.1 2 0 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 OWF53587.1 - 0.018 13.6 0.1 0.11 10.9 0.0 1.9 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Phage_holin_3_6 PF07332.11 OWF53588.1 - 0.081 13.0 3.4 0.33 11.0 0.3 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SLATT_5 PF18160.1 OWF53588.1 - 0.49 9.7 6.5 0.85 8.9 6.5 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Sulfatase PF00884.23 OWF53589.1 - 2.1e-66 224.5 0.2 3.4e-66 223.8 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 OWF53589.1 - 6.7e-07 30.1 0.0 1.5e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 OWF53589.1 - 1.3e-05 25.0 0.0 0.053 13.1 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 OWF53589.1 - 0.037 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Sulfatase PF00884.23 OWF53590.1 - 3.9e-64 217.0 0.4 4.9e-64 216.7 0.4 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF53590.1 - 8e-09 35.5 0.3 5.8e-08 32.7 0.1 2.3 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OWF53590.1 - 2.1e-06 28.5 0.0 4.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 OWF53590.1 - 0.024 13.2 0.0 0.044 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF229) DUF4994 PF16385.5 OWF53590.1 - 0.028 14.4 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF1501 PF07394.12 OWF53590.1 - 0.057 12.5 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RCC1 PF00415.18 OWF53591.1 - 3e-60 200.6 24.3 1.9e-13 50.8 1.9 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF53591.1 - 3.2e-37 125.6 29.6 1.4e-11 43.8 1.2 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OWF53591.1 - 1.5e-20 73.5 1.9 1.4e-19 70.3 0.4 2.4 1 1 1 2 2 2 1 BTB/POZ domain DcpS_C PF11969.8 OWF53592.1 - 1.3e-32 112.7 3.6 1.3e-32 112.7 3.6 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OWF53592.1 - 6.5e-16 58.9 1.5 1.5e-15 57.7 1.5 1.6 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 OWF53592.1 - 6.3e-14 52.2 1.2 1.8e-13 50.7 1.2 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 OWF53592.1 - 0.0021 18.4 1.7 0.0021 18.4 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF53592.1 - 0.0021 18.7 1.4 0.0021 18.7 1.4 2.5 2 1 1 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OWF53592.1 - 0.0047 17.2 5.5 0.0049 17.2 1.7 2.3 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OWF53592.1 - 0.042 14.2 0.1 0.042 14.2 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding 4HBT PF03061.22 OWF53593.1 - 6.6e-07 29.6 0.1 0.0029 17.9 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily T3SS_LEE_assoc PF13327.6 OWF53593.1 - 0.057 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Type III secretion system subunit zf-C2H2 PF00096.26 OWF53594.1 - 6.5e-13 48.4 41.0 0.00012 22.4 2.7 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF53594.1 - 4.9e-11 42.2 16.5 6.7e-07 28.9 2.9 5.3 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OWF53594.1 - 9.5e-11 41.6 37.0 0.0018 18.9 2.2 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF53594.1 - 4e-05 23.8 33.9 0.00028 21.2 2.4 6.4 6 0 0 6 6 6 2 Zinc-finger double domain zf-BED PF02892.15 OWF53594.1 - 0.0029 17.6 2.1 0.0029 17.6 2.1 4.7 4 1 1 5 5 5 1 BED zinc finger zf-C2HE PF16278.5 OWF53594.1 - 0.25 11.8 0.2 0.25 11.8 0.2 4.5 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger OrsD PF12013.8 OWF53594.1 - 0.31 11.5 0.1 0.31 11.5 0.1 4.9 3 1 3 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 OWF53594.1 - 0.94 9.8 13.5 27 5.2 0.1 5.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding TF_Zn_Ribbon PF08271.12 OWF53594.1 - 1.7 8.3 8.4 4.5 6.9 0.0 3.7 3 1 1 4 4 4 0 TFIIB zinc-binding zf-met PF12874.7 OWF53594.1 - 2.9 8.4 22.3 0.85 10.1 0.2 5.0 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Mdv1 PF11542.8 OWF53595.1 - 6.2e-05 22.9 4.6 13 5.8 0.0 6.4 2 2 7 9 9 9 3 Mitochondrial division protein 1 PMG PF05287.12 OWF53595.1 - 0.00097 19.2 3.9 0.17 11.9 0.8 2.2 1 1 1 2 2 2 2 PMG protein CTD PF12815.7 OWF53595.1 - 0.0015 19.0 15.8 0.075 13.6 7.7 2.3 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF2892 PF11127.8 OWF53595.1 - 0.007 16.4 5.9 2.1 8.4 0.3 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF2892) GCS PF03074.16 OWF53595.1 - 0.52 9.6 1.8 58 2.9 0.0 3.2 1 1 0 3 3 3 0 Glutamate-cysteine ligase PMG PF05287.12 OWF53596.1 - 2.2e-07 31.1 26.6 0.11 12.6 0.9 4.9 1 1 3 4 4 4 4 PMG protein Mdv1 PF11542.8 OWF53596.1 - 0.00067 19.6 21.9 59 3.7 0.1 11.8 3 3 13 17 17 17 1 Mitochondrial division protein 1 DUF2892 PF11127.8 OWF53596.1 - 0.011 15.8 26.0 7.8 6.6 0.5 7.2 1 1 5 6 6 6 0 Protein of unknown function (DUF2892) Mdv1 PF11542.8 OWF53597.1 - 2e-05 24.4 11.8 27 4.8 0.1 8.6 2 2 8 10 10 10 1 Mitochondrial division protein 1 CTD PF12815.7 OWF53597.1 - 0.00025 21.5 37.6 0.034 14.7 12.4 3.5 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF2892 PF11127.8 OWF53597.1 - 0.019 15.0 12.0 1.2 9.3 0.2 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF2892) PMG PF05287.12 OWF53597.1 - 0.035 14.1 11.0 0.079 13.0 1.5 2.9 1 1 2 3 3 3 0 PMG protein NCE101 PF11654.8 OWF53597.1 - 0.076 12.7 29.9 1e+02 2.7 0.0 12.2 12 1 2 14 14 14 0 Non-classical export protein 1 COPI_C PF06957.11 OWF53597.1 - 0.36 9.5 3.1 5.9 5.5 0.1 3.0 1 1 3 4 4 4 0 Coatomer (COPI) alpha subunit C-terminus TNF PF00229.18 OWF53598.1 - 6.4e-22 77.8 0.4 1e-21 77.2 0.4 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF53598.1 - 0.037 14.2 0.1 0.098 12.9 0.1 1.7 1 0 0 1 1 1 0 C1q domain BclA_C PF18573.1 OWF53598.1 - 0.29 11.1 2.8 3.1 7.7 2.8 2.2 1 1 0 1 1 1 0 BclA C-terminal domain TNF PF00229.18 OWF53599.1 - 1.1e-20 73.9 0.0 2.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 OWF53599.1 - 0.018 15.2 0.1 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 C1q domain Rab_bind PF16704.5 OWF53599.1 - 0.17 11.9 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Rab binding domain TNF PF00229.18 OWF53600.1 - 1.8e-26 92.6 0.0 3.4e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TMEM154 PF15102.6 OWF53600.1 - 0.0064 16.4 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family YpzG PF14139.6 OWF53601.1 - 0.05 13.8 0.9 11 6.2 0.1 2.9 2 0 0 2 2 2 0 YpzG-like protein LRR_8 PF13855.6 OWF53602.1 - 3.5e-30 103.5 34.8 1.1e-11 44.3 6.1 7.5 5 1 2 7 7 7 5 Leucine rich repeat TIR PF01582.20 OWF53602.1 - 8.2e-20 71.3 3.3 6.1e-10 39.2 0.0 2.8 3 0 0 3 3 3 2 TIR domain TIR_2 PF13676.6 OWF53602.1 - 6e-18 65.6 0.1 2.9e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 TIR domain LRR_5 PF13306.6 OWF53602.1 - 3.5e-10 39.9 13.3 4.7e-10 39.5 0.0 5.3 5 2 1 6 6 6 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OWF53602.1 - 5.4e-10 39.4 40.5 0.00082 19.7 0.3 8.9 8 2 1 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF53602.1 - 2.3e-05 24.3 23.0 2.3 9.1 0.1 10.1 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_9 PF14580.6 OWF53602.1 - 0.04 13.4 15.4 0.048 13.1 1.3 4.1 3 1 1 4 4 4 0 Leucine-rich repeat PglD_N PF17836.1 OWF53602.1 - 0.23 12.1 0.9 0.65 10.7 0.1 2.1 2 0 0 2 2 2 0 PglD N-terminal domain LRRNT PF01462.18 OWF53602.1 - 2.9 7.6 14.4 0.044 13.4 4.7 3.2 3 1 0 3 3 3 0 Leucine rich repeat N-terminal domain Surp PF01805.20 OWF53603.1 - 1e-45 153.5 7.2 1.6e-23 82.4 0.4 2.7 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 OWF53603.1 - 2.3e-43 148.6 9.4 2.3e-43 148.6 9.4 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 OWF53603.1 - 2.1e-13 49.8 0.0 6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OWF53603.1 - 0.051 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Fibrinogen_C PF00147.18 OWF53604.1 - 2.3e-55 187.8 4.1 2.7e-55 187.6 4.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain fn3 PF00041.21 OWF53605.1 - 0.012 15.9 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Fibronectin type III domain Cadherin_C_2 PF16492.5 OWF53605.1 - 0.086 13.6 0.0 0.7 10.7 0.0 2.7 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal fn3 PF00041.21 OWF53606.1 - 8.6e-05 22.8 0.0 0.00059 20.1 0.0 2.5 1 1 1 2 2 2 1 Fibronectin type III domain Phage_antitermQ PF06530.12 OWF53607.1 - 0.065 13.1 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q Y_phosphatase PF00102.27 OWF53608.1 - 1.3e-129 430.7 4.0 2e-76 256.7 0.9 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF53608.1 - 6e-13 48.8 0.1 1e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF53608.1 - 2e-05 24.8 0.0 0.077 13.1 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF53608.1 - 0.00092 19.2 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family EF-hand_1 PF00036.32 OWF53609.1 - 1.2e-11 43.3 7.6 0.0097 15.4 0.1 5.2 4 1 1 5 5 5 3 EF hand EF-hand_6 PF13405.6 OWF53609.1 - 9.9e-11 40.7 3.0 0.0091 15.9 0.0 5.2 3 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OWF53609.1 - 9.4e-10 38.8 3.5 1.9e-05 25.0 0.0 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF53609.1 - 2.4e-07 29.9 1.4 0.018 14.5 0.0 4.5 5 0 0 5 5 5 2 EF hand Dockerin_1 PF00404.18 OWF53609.1 - 0.0003 20.9 1.0 0.0021 18.2 0.1 2.4 2 1 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OWF53609.1 - 0.00075 19.8 2.5 0.039 14.3 0.2 2.9 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 OWF53609.1 - 1.7 8.6 7.5 39 4.2 0.0 4.2 4 1 0 4 4 4 0 EF-hand domain pair EF-hand_7 PF13499.6 OWF53611.1 - 1.3e-12 47.9 8.6 1.9e-06 28.3 0.3 2.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 OWF53611.1 - 1.8e-12 45.9 7.7 6.6e-05 22.2 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF53611.1 - 3.7e-12 45.1 9.4 4.8e-06 26.1 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF53611.1 - 1.5e-10 40.1 4.7 0.0002 20.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OWF53611.1 - 0.0065 16.3 4.7 2 8.3 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair Dockerin_1 PF00404.18 OWF53611.1 - 0.0075 16.4 0.0 38 4.6 0.0 3.1 3 0 0 3 3 3 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OWF53611.1 - 0.057 13.7 2.3 6.8 7.0 0.0 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region MRG PF05712.13 OWF53611.1 - 0.062 12.6 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 MRG NIF PF03031.18 OWF53612.1 - 1.7e-54 183.8 0.0 2.2e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sulfotransfer_3 PF13469.6 OWF53613.1 - 5.9e-14 53.0 0.1 9.4e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF53613.1 - 3.4e-13 49.7 0.0 7.5e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Peptidase_C14 PF00656.22 OWF53614.1 - 1.4e-21 77.6 0.0 2.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 OWF53614.1 - 6.2e-17 61.4 0.1 1.1e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF53614.1 - 4.9e-07 29.7 0.0 7.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Caspase recruitment domain Peptidase_C14 PF00656.22 OWF53615.1 - 2.3e-21 76.9 0.1 2.3e-21 76.9 0.1 1.7 2 0 0 2 2 2 1 Caspase domain CARD PF00619.21 OWF53615.1 - 3.3e-17 62.3 0.1 6.8e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF53615.1 - 1.7e-06 27.9 0.1 2.8e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Caspase recruitment domain Amidoligase_2 PF12224.8 OWF53615.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme SOG2 PF10428.9 OWF53615.1 - 1.1 8.4 10.8 1.4 8.0 10.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 OWF53615.1 - 2.3 6.8 8.1 2.8 6.5 8.1 1.2 1 0 0 1 1 1 0 Hamartin protein CARD PF00619.21 OWF53617.1 - 6.9e-14 51.6 0.0 1.1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF53617.1 - 4e-08 33.2 0.0 5.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Caspase recruitment domain Ly49 PF08391.10 OWF53618.1 - 0.00025 21.4 2.3 0.00025 21.4 2.3 2.1 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region RIFIN PF02009.16 OWF53618.1 - 0.00094 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 OWF53618.1 - 0.023 15.0 1.9 0.037 14.3 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF3969 PF13108.6 OWF53618.1 - 0.19 11.8 0.0 0.53 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) MAGE_N PF12440.8 OWF53618.1 - 0.23 12.1 4.9 0.49 11.1 4.9 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Sid-5 PF17204.3 OWF53618.1 - 3 8.1 5.7 0.39 10.9 0.7 2.1 2 0 0 2 2 2 0 Sid-5 family Acyl_transf_3 PF01757.22 OWF53619.1 - 4.5e-21 75.3 33.7 8.2e-21 74.4 33.7 1.4 1 0 0 1 1 1 1 Acyltransferase family TB2_DP1_HVA22 PF03134.19 OWF53619.1 - 0.013 15.4 2.4 0.013 15.4 2.4 2.8 2 0 0 2 2 2 0 TB2/DP1, HVA22 family DUF4370 PF14290.6 OWF53619.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) Acyl_transf_3 PF01757.22 OWF53620.1 - 1.2e-24 87.0 34.7 1.9e-24 86.4 34.7 1.2 1 0 0 1 1 1 1 Acyltransferase family Clathrin_bdg PF15045.6 OWF53620.1 - 2 8.4 8.3 46 4.1 0.1 4.2 4 0 0 4 4 4 0 Clathrin-binding box of Aftiphilin, vesicle trafficking TB2_DP1_HVA22 PF03134.19 OWF53620.1 - 5.4 7.0 13.4 0.041 13.8 3.0 2.8 3 0 0 3 3 3 0 TB2/DP1, HVA22 family MotB_plug PF13677.6 OWF53620.1 - 7.5 6.2 10.0 6.5 6.4 0.1 4.6 4 0 0 4 4 4 0 Membrane MotB of proton-channel complex MotA/MotB Peptidase_M13_N PF05649.13 OWF53621.1 - 6.3e-122 407.9 0.1 8.4e-122 407.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF53621.1 - 4.9e-75 251.6 0.0 8.2e-75 250.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M4 PF01447.18 OWF53621.1 - 0.12 12.9 0.9 0.41 11.1 0.9 2.0 1 1 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Atrophin-1 PF03154.15 OWF53622.1 - 2.1e-37 129.0 48.6 1.8e-30 106.1 40.6 5.7 1 1 2 4 4 4 2 Atrophin-1 family BAH PF01426.18 OWF53622.1 - 2.9e-16 59.4 0.0 8.1e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 BAH domain ELM2 PF01448.24 OWF53622.1 - 9.7e-10 39.1 0.1 4.2e-09 37.0 0.1 2.2 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 OWF53622.1 - 0.00016 21.7 0.5 0.00016 21.7 0.5 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OWF53622.1 - 0.0013 18.6 0.6 0.006 16.4 0.6 2.1 1 0 0 1 1 1 1 Myb DNA-binding like GATA PF00320.27 OWF53622.1 - 0.0055 16.3 6.8 0.0055 16.3 6.8 2.0 2 0 0 2 2 2 1 GATA zinc finger Myb_DNA-bind_6 PF13921.6 OWF53622.1 - 0.046 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain 7TM_GPCR_Srw PF10324.9 OWF53623.1 - 2.1e-34 119.3 12.7 2.9e-34 118.8 12.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF53623.1 - 1.8e-17 63.6 7.8 2.9e-17 62.9 7.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 OWF53624.1 - 2.4e-46 158.0 25.2 3.2e-46 157.6 25.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 OWF53624.1 - 2.4e-14 53.6 3.3 6.2e-14 52.2 3.3 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 OWF53624.1 - 5.5e-13 48.8 1.2 9.3e-13 48.1 1.2 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain HRM PF02793.22 OWF53624.1 - 3.4e-05 24.0 0.5 8.1e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 Hormone receptor domain EXOSC1 PF10447.9 OWF53624.1 - 0.15 12.7 2.5 0.28 11.8 0.2 2.2 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Ig_3 PF13927.6 OWF53625.1 - 5.9e-58 193.4 43.0 4.8e-13 49.5 4.6 5.2 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 OWF53625.1 - 7.4e-52 173.4 17.6 1.3e-11 44.4 0.3 5.2 5 0 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 OWF53625.1 - 1.2e-46 156.7 40.5 1.5e-09 37.9 0.9 5.2 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 OWF53625.1 - 1.1e-36 125.1 37.8 5.9e-08 33.0 1.4 5.3 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 OWF53625.1 - 2.2e-31 108.3 36.1 5e-07 29.9 2.9 9.0 5 5 0 5 5 5 5 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 OWF53625.1 - 7.2e-07 29.2 11.2 5.9 7.0 0.0 6.4 5 2 0 5 5 5 3 C17orf99 Ig domain Ig_5 PF16681.5 OWF53625.1 - 1.2e-06 28.8 6.8 0.94 9.9 0.0 6.3 5 4 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF53625.1 - 1.7e-06 27.5 2.2 1.6 8.3 0.0 5.0 5 0 0 5 5 5 2 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 OWF53625.1 - 3.3e-06 26.8 19.8 0.067 13.0 0.3 5.4 5 0 0 5 5 5 3 Adenovirus E3 region protein CR1 Lep_receptor_Ig PF06328.11 OWF53625.1 - 0.0038 17.1 26.2 2 8.4 0.1 6.1 5 2 0 5 5 5 2 Ig-like C2-type domain C1-set PF07654.15 OWF53625.1 - 0.017 15.5 14.8 0.018 15.4 1.1 4.9 5 0 0 5 5 5 0 Immunoglobulin C1-set domain Reprolysin_4 PF13583.6 OWF53625.1 - 0.1 12.2 25.1 0.16 11.6 2.8 3.7 3 1 0 4 4 4 0 Metallo-peptidase family M12B Reprolysin-like DUF5044 PF16447.5 OWF53625.1 - 0.14 12.0 2.3 4.8 7.0 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5044) MucB_RseB_C PF17188.4 OWF53625.1 - 0.81 9.9 3.7 10 6.4 0.3 3.4 3 0 0 3 3 3 0 MucB/RseB C-terminal domain Laminin_II PF06009.12 OWF53626.1 - 4.5e-05 23.5 2.1 6.9e-05 22.9 2.1 1.3 1 0 0 1 1 1 1 Laminin Domain II Apolipoprotein PF01442.18 OWF53626.1 - 0.00029 20.7 0.9 0.00047 20.1 0.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain fn3 PF00041.21 OWF53626.1 - 0.00093 19.5 0.5 0.0024 18.2 0.1 1.9 2 0 0 2 2 1 1 Fibronectin type III domain IDEAL PF08858.10 OWF53626.1 - 0.042 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 IDEAL domain Translin PF01997.16 OWF53626.1 - 0.047 13.7 0.4 0.076 13.0 0.4 1.3 1 0 0 1 1 1 0 Translin family Pur_ac_phosph_N PF16656.5 OWF53626.1 - 0.054 14.1 0.1 0.16 12.6 0.1 1.8 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Baculo_PEP_C PF04513.12 OWF53626.1 - 0.073 13.1 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.9 OWF53626.1 - 0.12 12.6 2.5 0.22 11.7 2.5 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FlgN PF05130.12 OWF53626.1 - 0.15 12.6 4.1 0.12 12.9 2.8 1.4 2 0 0 2 2 1 0 FlgN protein DUF745 PF05335.13 OWF53626.1 - 0.17 11.6 2.8 0.24 11.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FUSC PF04632.12 OWF53626.1 - 0.2 10.2 0.2 0.26 9.8 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phasin PF05597.11 OWF53626.1 - 0.21 11.6 2.8 0.52 10.3 2.1 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3584 PF12128.8 OWF53626.1 - 0.27 8.7 3.9 0.35 8.3 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 OWF53626.1 - 0.28 11.3 2.0 0.57 10.4 2.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pex19 PF04614.12 OWF53626.1 - 0.3 10.8 3.7 0.38 10.5 3.7 1.1 1 0 0 1 1 1 0 Pex19 protein family CHDCT2 PF08074.11 OWF53626.1 - 0.48 10.6 2.0 0.71 10.0 2.0 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain LBP_BPI_CETP PF01273.25 OWF53627.1 - 0.02 14.5 0.0 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain HAMP_N3 PF18575.1 OWF53627.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Arg_decarbox_C PF17944.1 OWF53627.1 - 0.096 13.3 0.0 0.68 10.5 0.0 2.4 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension RMI1_N PF08585.12 OWF53628.1 - 2.7e-50 171.2 0.6 2.7e-50 171.2 0.6 2.0 2 0 0 2 2 2 1 RecQ mediated genome instability protein RMI1_C PF16099.5 OWF53628.1 - 1.2e-38 132.1 0.0 2.2e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold tRNA_anti-codon PF01336.25 OWF53628.1 - 0.11 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain YjhX_toxin PF09857.9 OWF53629.1 - 0.0085 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative toxin of bacterial toxin-antitoxin pair Fringe PF02434.16 OWF53630.1 - 8.2e-19 68.0 1.3 2.5e-18 66.5 1.3 1.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF53630.1 - 1e-10 41.8 0.0 2.9e-06 27.2 0.1 2.3 1 1 1 2 2 2 2 Galactosyltransferase Ank_2 PF12796.7 OWF53631.1 - 9.8e-33 112.6 9.4 3e-09 37.4 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OWF53631.1 - 9.4e-23 79.6 0.4 8.3e-06 26.0 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OWF53631.1 - 5.4e-21 74.4 3.4 5.1e-08 33.0 0.4 6.3 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF53631.1 - 3.7e-19 68.8 6.8 3.5e-06 27.5 0.0 7.0 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Patatin PF01734.22 OWF53631.1 - 1e-17 65.0 0.0 3.1e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase Ank_3 PF13606.6 OWF53631.1 - 3.9e-11 42.2 0.3 0.00032 20.9 0.0 6.0 7 1 0 7 7 7 2 Ankyrin repeat Glycos_transf_N PF04413.16 OWF53633.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) EPTP PF03736.17 OWF53635.1 - 0.063 13.3 6.6 26 4.9 0.1 4.9 5 0 0 5 5 5 0 EPTP domain DUF1830 PF08865.11 OWF53635.1 - 0.088 12.8 0.9 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1830) Phg_2220_C PF09524.10 OWF53635.1 - 0.49 10.5 7.7 6.1 7.0 0.4 3.1 1 1 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) DUF1617 PF07761.12 OWF53635.1 - 3 7.9 6.5 6.3 6.9 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1617) MMR_HSR1_Xtn PF16897.5 OWF53635.1 - 3.2 7.8 12.9 6.6 6.8 1.1 2.7 1 1 2 3 3 3 0 C-terminal region of MMR_HSR1 domain GFRP PF06399.13 OWF53636.1 - 0.00048 19.9 2.4 4.6 7.2 0.1 3.2 1 1 2 3 3 3 3 GTP cyclohydrolase I feedback regulatory protein (GFRP) Spore_YhaL PF14147.6 OWF53636.1 - 0.038 13.7 0.0 18 5.1 0.0 2.9 3 0 0 3 3 3 0 Sporulation protein YhaL ZT_dimer PF16916.5 OWF53636.1 - 0.21 11.7 15.4 2.4 8.4 1.3 3.1 1 1 2 3 3 3 0 Dimerisation domain of Zinc Transporter ATP-grasp_4 PF13535.6 OWF53636.1 - 0.33 10.5 16.2 2.8 7.5 1.2 3.0 1 1 2 3 3 3 0 ATP-grasp domain pP_pnuc_2 PF18166.1 OWF53636.1 - 0.52 10.4 14.0 11 6.2 0.5 3.4 1 1 2 3 3 3 0 Predicted pPIWI-associating nuclease Bee_toxin PF17454.2 OWF53636.1 - 2.1 8.5 9.0 8.1 6.6 0.3 3.2 2 1 1 3 3 3 0 Honey bee toxin DUF1617 PF07761.12 OWF53636.1 - 4.9 7.2 13.0 10 6.2 2.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1617) DUF1830 PF08865.11 OWF53637.1 - 1.3 9.0 9.0 20 5.3 0.1 4.6 3 2 2 6 6 6 0 Domain of unknown function (DUF1830) Phg_2220_C PF09524.10 OWF53637.1 - 5.5 7.1 16.6 4.9 7.3 0.2 5.1 1 1 5 7 7 7 0 Conserved phage C-terminus (Phg_2220_C) TSP_1 PF00090.19 OWF53638.1 - 1.6e-07 31.4 5.5 1.6e-07 31.4 5.5 5.2 6 0 0 6 6 6 2 Thrombospondin type 1 domain VWD PF00094.25 OWF53639.1 - 0.021 15.1 1.0 2.9 8.1 0.2 2.1 1 1 1 2 2 2 0 von Willebrand factor type D domain Tcp10_C PF07202.13 OWF53639.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.4 1 1 0 1 1 1 0 T-complex protein 10 C-terminus WD40 PF00400.32 OWF53640.1 - 1.4e-28 98.5 19.8 1.2e-07 32.3 0.9 7.7 8 0 0 8 8 7 6 WD domain, G-beta repeat zf-TRAF PF02176.18 OWF53640.1 - 3.9e-08 33.9 6.4 3.9e-08 33.9 6.4 2.9 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 OWF53640.1 - 3.2e-06 27.2 6.7 1e-05 25.6 6.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF53640.1 - 5.7e-06 26.3 8.6 2.4e-05 24.2 8.6 2.2 1 0 0 1 1 1 1 RING-type zinc-finger WD40_like PF17005.5 OWF53640.1 - 1.3e-05 24.6 1.6 0.00013 21.4 0.4 2.5 1 1 1 2 2 2 2 WD40-like domain zf-C3HC4_3 PF13920.6 OWF53640.1 - 3.1e-05 23.8 4.9 3.1e-05 23.8 4.9 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Nup160 PF11715.8 OWF53640.1 - 3.6e-05 22.6 4.3 0.14 10.8 0.0 3.6 2 1 1 4 4 4 2 Nucleoporin Nup120/160 zf-RING_5 PF14634.6 OWF53640.1 - 6.2e-05 22.9 6.4 6.2e-05 22.9 6.4 3.3 3 1 0 3 3 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OWF53640.1 - 7e-05 22.6 7.4 0.00041 20.2 7.4 2.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF53640.1 - 8.2e-05 22.4 7.3 8.2e-05 22.4 7.3 2.9 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF53640.1 - 0.00019 21.2 5.8 0.00019 21.2 5.8 2.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ACC PF17848.1 OWF53640.1 - 0.0033 17.5 0.9 0.44 10.7 0.1 3.2 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf-RING_6 PF14835.6 OWF53640.1 - 0.0036 17.1 1.7 0.0036 17.1 1.7 2.1 2 0 0 2 2 1 1 zf-RING of BARD1-type protein EzrA PF06160.12 OWF53640.1 - 0.0086 14.3 1.9 0.013 13.7 1.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA zf-TRAF_2 PF15965.5 OWF53640.1 - 0.013 15.9 6.0 0.013 15.9 6.0 3.4 2 1 1 3 3 2 0 TRAF-like zinc-finger Sina PF03145.16 OWF53640.1 - 0.016 15.2 10.8 0.037 14.0 1.9 2.5 1 1 1 2 2 2 0 Seven in absentia protein family CPSF_A PF03178.15 OWF53640.1 - 0.023 14.0 0.8 0.96 8.7 0.0 2.8 2 1 1 3 3 2 0 CPSF A subunit region HMMR_N PF15905.5 OWF53640.1 - 0.041 13.4 4.2 0.063 12.8 4.2 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CEP63 PF17045.5 OWF53640.1 - 0.043 13.7 9.8 0.019 14.9 5.2 2.0 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF1664 PF07889.12 OWF53640.1 - 0.043 13.8 5.0 0.11 12.5 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 OWF53640.1 - 0.046 13.6 0.7 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RmuC PF02646.16 OWF53640.1 - 0.071 12.2 1.9 0.13 11.4 1.9 1.4 1 0 0 1 1 1 0 RmuC family W_rich_C PF07483.11 OWF53640.1 - 0.089 13.0 1.8 6.8 6.9 0.0 3.6 3 1 1 4 4 4 0 Tryptophan-rich Synechocystis species C-terminal domain Cob_adeno_trans PF01923.18 OWF53640.1 - 0.091 12.9 0.2 0.46 10.6 0.2 2.0 1 1 0 1 1 1 0 Cobalamin adenosyltransferase CorA PF01544.18 OWF53640.1 - 0.23 10.7 2.1 0.42 9.9 2.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TolA_bind_tri PF16331.5 OWF53640.1 - 0.24 11.5 5.6 0.24 11.5 3.7 1.9 1 1 1 2 2 2 0 TolA binding protein trimerisation GAS PF13851.6 OWF53640.1 - 0.28 10.5 7.3 0.54 9.6 7.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 OWF53640.1 - 0.32 10.3 6.9 0.58 9.5 6.9 1.3 1 0 0 1 1 1 0 Tropomyosin Tup_N PF08581.10 OWF53640.1 - 0.33 11.3 4.9 1.1 9.7 4.9 1.8 1 0 0 1 1 1 0 Tup N-terminal Laminin_II PF06009.12 OWF53640.1 - 0.63 10.0 3.3 1.3 9.1 3.3 1.4 1 0 0 1 1 1 0 Laminin Domain II Tropomyosin_1 PF12718.7 OWF53640.1 - 0.72 10.0 6.9 1.3 9.2 6.9 1.4 1 0 0 1 1 1 0 Tropomyosin like FlaC_arch PF05377.11 OWF53640.1 - 1.5 9.3 8.3 1.2 9.6 1.2 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 OWF53640.1 - 2.9 8.0 7.2 0.84 9.7 4.0 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-U11-48K PF05253.12 OWF53640.1 - 3 7.9 7.7 2.5 8.1 0.0 3.6 4 0 0 4 4 3 0 U11-48K-like CHHC zinc finger 7tm_1 PF00001.21 OWF53641.1 - 6.2e-07 29.0 3.1 8.4e-07 28.6 3.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF53641.1 - 5e-05 22.7 4.8 6.2e-05 22.4 4.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw bZIP_1 PF00170.21 OWF53641.1 - 0.0058 16.7 1.8 0.0058 16.7 1.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor XhlA PF10779.9 OWF53641.1 - 0.0091 16.2 1.5 0.024 14.8 1.5 1.8 1 0 0 1 1 1 1 Haemolysin XhlA DUF737 PF05300.11 OWF53641.1 - 0.05 14.0 1.4 0.071 13.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF3552 PF12072.8 OWF53641.1 - 0.082 12.3 4.1 0.12 11.8 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SelK_SelG PF10961.8 OWF53641.1 - 1.1 10.0 3.9 0.66 10.6 1.1 2.0 2 0 0 2 2 2 0 Selenoprotein SelK_SelG 7tm_1 PF00001.21 OWF53642.1 - 8e-42 143.4 32.1 1.3e-41 142.7 32.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF53642.1 - 3.5e-08 33.1 30.8 6.7e-08 32.2 30.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF53642.1 - 3e-05 23.8 31.3 3e-05 23.8 31.3 2.5 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx HLH PF00010.26 OWF53644.1 - 3.1e-16 59.1 2.3 5.7e-16 58.2 2.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2935 PF11155.8 OWF53646.1 - 0.038 14.3 0.2 11 6.4 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Speriolin_N PF15058.6 OWF53646.1 - 0.28 11.2 5.0 1.7 8.7 5.0 1.9 1 1 0 1 1 1 0 Speriolin N terminus Speriolin_N PF15058.6 OWF53647.1 - 0.041 14.0 10.0 0.13 12.4 7.4 2.3 1 1 1 2 2 2 0 Speriolin N terminus DUF4376 PF14301.6 OWF53647.1 - 0.28 11.6 1.3 6 7.3 0.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4376) DUF2935 PF11155.8 OWF53648.1 - 0.0021 18.4 4.7 11 6.4 0.0 4.4 1 1 1 4 4 4 1 Domain of unknown function (DUF2935) bMG5 PF17972.1 OWF53648.1 - 0.0033 17.8 0.1 28 5.1 0.0 3.8 1 1 3 4 4 4 0 Bacterial Alpha-2-macroglobulin MG5 domain Importin_rep_6 PF18829.1 OWF53648.1 - 0.036 14.2 0.0 30 4.8 0.0 4.2 2 2 3 6 6 6 0 Importin repeat 6 U3snoRNP10 PF12397.8 OWF53648.1 - 0.042 14.2 0.2 4.5 7.6 0.0 3.3 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Speriolin_N PF15058.6 OWF53648.1 - 0.092 12.8 12.9 14 5.7 7.2 3.1 1 1 1 2 2 2 0 Speriolin N terminus DUF1684 PF07920.11 OWF53648.1 - 0.1 12.8 0.5 0.1 12.8 0.5 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1684) Dynamin_M PF01031.20 OWF53648.1 - 2.7 7.2 9.8 13 4.8 0.2 4.2 1 1 4 5 5 5 0 Dynamin central region DUF4376 PF14301.6 OWF53649.1 - 0.27 11.6 1.8 5.4 7.4 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4376) Speriolin_N PF15058.6 OWF53649.1 - 0.32 11.1 5.8 0.29 11.2 1.6 1.9 1 1 1 2 2 2 0 Speriolin N terminus DUF1684 PF07920.11 OWF53649.1 - 3.5 7.9 12.4 7.1 6.9 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1684) Acyl_transf_3 PF01757.22 OWF53651.1 - 1.3e-22 80.3 39.9 2.1e-22 79.7 39.9 1.3 1 0 0 1 1 1 1 Acyltransferase family Coatomer_WDAD PF04053.14 OWF53652.1 - 3.8e-171 570.0 0.1 6.3e-171 569.3 0.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 OWF53652.1 - 4.7e-43 144.3 8.4 4.4e-08 33.6 0.0 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF53652.1 - 8.6e-09 35.6 0.2 2.4 8.5 0.0 6.6 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OWF53652.1 - 0.00042 20.3 0.1 4.1 7.5 0.0 3.8 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region UPF0167 PF03691.14 OWF53652.1 - 0.0077 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0167) Frtz PF11768.8 OWF53652.1 - 0.092 11.0 0.0 3 6.1 0.0 2.5 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz UAE_UbL PF14732.6 OWF53652.1 - 0.47 11.1 4.0 1.8 9.2 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain TMEM107 PF14995.6 OWF53653.1 - 1.1e-44 151.8 8.0 1.2e-44 151.6 8.0 1.0 1 0 0 1 1 1 1 Transmembrane protein ODV-E18 PF10717.9 OWF53653.1 - 0.032 14.1 0.4 0.032 14.1 0.4 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 MRP-L51 PF10244.9 OWF53654.1 - 7e-25 87.1 0.4 1.1e-24 86.4 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit MULE PF10551.9 OWF53655.1 - 0.048 14.1 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 MULE transposase domain Pneumovirus_M2 PF06436.11 OWF53655.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) DUF5572 PF17733.1 OWF53656.1 - 3.2e-07 30.1 0.8 5.9e-07 29.2 0.8 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Ank_2 PF12796.7 OWF53657.1 - 3.1e-20 72.5 0.3 2.8e-15 56.7 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53657.1 - 1.8e-14 53.9 0.5 1.7e-08 34.8 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF53657.1 - 2.2e-14 53.3 0.4 1.7e-06 28.2 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF53657.1 - 1.3e-12 47.5 0.2 1.5e-05 25.2 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OWF53657.1 - 5.7e-12 44.7 0.1 1.7e-05 24.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Beta-Casp PF10996.8 OWF53658.1 - 1.7e-09 37.9 0.7 3.2 8.1 0.0 6.5 2 2 5 7 7 7 3 Beta-Casp domain DUF5511 PF17630.2 OWF53658.1 - 2.4e-06 27.6 0.8 1.4 9.2 0.1 5.0 4 1 1 5 5 5 1 Family of unknown function (DUF5511) zf-TAZ PF02135.16 OWF53658.1 - 0.00013 22.4 15.1 0.26 11.8 0.8 3.7 1 1 3 4 4 4 4 TAZ zinc finger cpYpsA PF12694.7 OWF53658.1 - 0.0015 18.3 6.5 0.24 11.2 0.5 3.2 1 1 2 3 3 3 2 Circularly permutated YpsA SLOG family DUF4854 PF16146.5 OWF53658.1 - 0.047 14.0 5.4 33 4.9 0.1 4.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4854) EVI2A PF05399.11 OWF53658.1 - 0.43 10.1 8.1 2.1 7.9 1.3 2.5 1 1 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) AAT PF03417.16 OWF53658.1 - 0.52 10.0 18.8 4.7 6.8 0.6 4.4 1 1 4 5 5 5 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SH2 PF00017.24 OWF53658.1 - 0.89 9.7 7.9 14 5.9 0.2 3.8 1 1 3 4 4 4 0 SH2 domain zinc-ribbons_6 PF07191.12 OWF53658.1 - 0.95 9.5 18.9 13 5.8 0.6 4.9 1 1 3 4 4 4 0 zinc-ribbons NFACT-R_2 PF18297.1 OWF53658.1 - 1.3 9.3 9.0 9.4 6.5 0.1 4.7 2 2 3 5 5 5 0 NFACT protein RNA binding domain FANCAA PF15146.6 OWF53659.1 - 1e-07 31.4 2.8 1.1e-06 28.1 0.2 2.4 2 0 0 2 2 2 2 Fanconi anemia-associated CD225 PF04505.12 OWF53660.1 - 1.3e-07 31.6 4.8 2e-07 31.0 4.8 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Glutaredoxin PF00462.24 OWF53661.1 - 1.6e-10 41.0 0.4 4.6e-10 39.6 0.2 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 OWF53661.1 - 2.9e-08 34.0 0.1 5.7e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF53661.1 - 0.00037 20.8 0.0 0.00085 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF53661.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF53661.1 - 0.0015 18.8 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF53661.1 - 0.0016 19.2 0.1 0.022 15.5 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase N-terminal domain DUF836 PF05768.14 OWF53661.1 - 0.017 15.5 0.3 0.037 14.4 0.3 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_C_3 PF14497.6 OWF53661.1 - 0.019 15.1 0.1 0.076 13.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF53661.1 - 0.023 14.9 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OWF53661.1 - 0.097 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PB1 PF00564.24 OWF53662.1 - 1.6e-11 43.9 0.4 2.7e-11 43.3 0.4 1.3 1 0 0 1 1 1 1 PB1 domain GREB1 PF15782.5 OWF53662.1 - 6.6 3.7 15.7 8.6 3.3 15.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3533 PF12051.8 OWF53662.1 - 6.8 5.5 5.3 9.5 5.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MFS_1 PF07690.16 OWF53663.1 - 1.2e-35 123.1 40.2 9.1e-34 116.9 29.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arm PF00514.23 OWF53664.1 - 0.00092 19.2 2.9 5.4 7.2 0.3 5.7 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat VWD PF00094.25 OWF53665.1 - 3.1e-18 66.5 2.8 3.2e-18 66.5 0.8 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain Innexin PF00876.18 OWF53666.1 - 1.9e-126 422.1 12.1 2.2e-126 421.9 12.1 1.0 1 0 0 1 1 1 1 Innexin Clusterin PF01093.17 OWF53668.1 - 0.00017 20.8 5.0 0.0082 15.2 0.0 2.2 2 0 0 2 2 2 2 Clusterin Ldl_recept_a PF00057.18 OWF53669.1 - 6.7e-05 23.0 5.7 0.0001 22.4 5.7 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A SelP_N PF04592.14 OWF53669.1 - 1.9 7.8 13.1 2.7 7.3 13.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CENP-B_dimeris PF09026.10 OWF53669.1 - 5.1 7.5 8.4 8.5 6.8 8.4 1.4 1 1 0 1 1 1 0 Centromere protein B dimerisation domain SRCR PF00530.18 OWF53670.1 - 5.4e-117 383.0 29.0 6.1e-24 84.4 1.0 6.1 6 0 0 6 6 6 6 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF53670.1 - 1e-28 99.8 26.8 3.4e-05 24.3 0.6 6.5 6 0 0 6 6 6 6 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF53670.1 - 1.5e-12 48.0 6.7 0.33 11.5 0.2 6.2 6 0 0 6 6 6 4 Hepsin, SRCR domain DUF3552 PF12072.8 OWF53671.1 - 0.00087 18.8 9.5 0.63 9.4 0.5 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) Myosin_tail_1 PF01576.19 OWF53671.1 - 0.0046 14.9 18.1 0.035 11.9 18.0 1.8 1 1 0 1 1 1 1 Myosin tail KELK PF15796.5 OWF53671.1 - 0.0091 16.4 12.3 2.2 8.8 1.0 3.7 1 1 4 5 5 5 3 KELK-motif containing domain of MRCK Ser/Thr protein kinase APG6_N PF17675.1 OWF53671.1 - 0.018 15.5 14.2 0.26 11.8 0.6 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region Cytadhesin_P30 PF07271.11 OWF53671.1 - 0.024 14.2 13.9 0.68 9.4 1.9 3.3 1 1 2 3 3 3 0 Cytadhesin P30/P32 Sec34 PF04136.15 OWF53671.1 - 0.082 12.8 32.7 2.6 7.9 4.7 4.7 1 1 4 5 5 5 0 Sec34-like family Phage_sheath_1N PF17481.2 OWF53671.1 - 0.22 12.0 2.4 45 4.6 2.4 4.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain CALCOCO1 PF07888.11 OWF53671.1 - 0.22 10.3 20.0 2.2 7.1 8.8 2.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Jnk-SapK_ap_N PF09744.9 OWF53671.1 - 0.32 11.2 39.0 0.13 12.5 3.2 4.1 1 1 2 3 3 2 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 OWF53671.1 - 0.81 9.7 19.8 5.6 7.0 7.9 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.6 OWF53671.1 - 1.2 9.3 21.1 4.2 7.5 4.7 3.0 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF5344 PF17279.2 OWF53671.1 - 2.2 8.9 27.7 3.9 8.1 2.1 4.7 1 1 4 5 5 5 0 Family of unknown function (DUF5344) SHE3 PF17078.5 OWF53671.1 - 2.9 7.6 52.0 2.2 8.0 8.0 4.4 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Spc24 PF08286.11 OWF53671.1 - 4.8 7.5 34.2 12 6.2 3.5 5.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Fez1 PF06818.15 OWF53671.1 - 5.6 7.4 25.1 5.3 7.4 6.5 2.4 1 1 1 2 2 2 0 Fez1 DUF3450 PF11932.8 OWF53671.1 - 8.9 5.5 26.8 8.4 5.6 8.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 OWF53671.1 - 9.3 5.1 41.7 1.8 7.4 17.5 2.3 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Neur_chan_LBD PF02931.23 OWF53672.1 - 2.5e-42 144.8 0.0 3.9e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF53672.1 - 1.8e-14 54.4 1.4 2.8e-14 53.8 1.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region EVC2_like PF12297.8 OWF53672.1 - 0.042 12.5 0.1 0.063 11.9 0.1 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Saf_2TM PF18303.1 OWF53672.1 - 0.062 12.9 0.1 0.062 12.9 0.1 2.7 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain DUF2417 PF10329.9 OWF53672.1 - 0.2 11.0 8.1 0.95 8.8 5.0 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) MYCBPAP PF14646.6 OWF53673.1 - 2.7e-138 461.6 0.1 3.9e-138 461.1 0.1 1.2 1 0 0 1 1 1 1 MYCBP-associated protein family CSTF_C PF14304.6 OWF53673.1 - 0.00085 18.9 1.4 0.0038 16.8 0.2 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Rotamase_3 PF13616.6 OWF53674.1 - 2.1e-19 70.2 0.1 5.6e-19 68.8 0.1 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OWF53674.1 - 1.6e-14 54.6 0.0 3e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OWF53674.1 - 0.01 16.7 0.0 0.013 16.3 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF3752 PF12572.8 OWF53675.1 - 3.6e-27 95.8 13.4 3.6e-27 95.8 13.4 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF3752) Amidohydro_1 PF01979.20 OWF53676.1 - 1.8e-74 251.1 0.0 2.1e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OWF53676.1 - 9.4e-07 28.6 0.0 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family S-methyl_trans PF02574.16 OWF53677.1 - 7.2e-75 252.3 0.0 8.1e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DeoC PF01791.9 OWF53677.1 - 0.0055 16.4 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 2 DeoC/LacD family aldolase Rad60-SLD PF11976.8 OWF53677.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NAR2 PF16974.5 OWF53677.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory DUF3798 PF12683.7 OWF53677.1 - 0.049 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) FAM194 PF14977.6 OWF53678.1 - 3e-69 232.4 0.0 6.4e-69 231.3 0.0 1.6 1 0 0 1 1 1 1 FAM194 protein MFS_1 PF07690.16 OWF53679.1 - 2e-23 82.9 23.8 2e-23 82.9 23.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OWF53679.1 - 0.0042 15.7 8.2 0.0042 15.7 8.2 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein Collagen PF01391.18 OWF53680.1 - 4.1e-214 692.7 737.3 1.6e-09 37.4 20.9 29.9 5 5 21 26 26 26 25 Collagen triple helix repeat (20 copies) C4 PF01413.19 OWF53680.1 - 1.2e-81 270.4 2.5 5.2e-44 149.2 0.2 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 OWF53681.1 - 4.9e-196 634.7 607.0 1.9e-09 37.1 16.5 27.6 5 5 20 26 26 26 26 Collagen triple helix repeat (20 copies) C4 PF01413.19 OWF53681.1 - 2.4e-74 246.8 2.2 1.2e-36 125.4 0.1 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Tetraspanin PF00335.20 OWF53682.1 - 7.7e-54 182.8 12.4 8.7e-54 182.6 12.4 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF5540 PF17694.1 OWF53682.1 - 1.5 9.4 4.1 4.9 7.7 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5540) GRIP PF01465.20 OWF53683.1 - 1.8e-16 59.7 0.3 7.2e-16 57.8 0.3 2.2 1 0 0 1 1 1 1 GRIP domain Rab_bind PF16704.5 OWF53683.1 - 1.3e-12 47.5 7.4 1.3e-12 47.5 7.4 9.2 9 0 0 9 9 9 1 Rab binding domain CENP-F_leu_zip PF10473.9 OWF53683.1 - 1e-11 45.1 75.1 3.3e-09 36.9 14.3 21.3 6 4 13 20 20 20 10 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 OWF53683.1 - 0.0053 17.3 8.0 0.0053 17.3 8.0 25.5 4 3 23 28 28 28 2 Clathrin-binding domain of Huntingtin-interacting protein 1 RVT_3 PF13456.6 OWF53683.1 - 0.012 15.4 2.4 0.099 12.5 0.4 3.9 2 0 0 2 2 2 0 Reverse transcriptase-like HALZ PF02183.18 OWF53683.1 - 0.049 13.9 0.1 0.049 13.9 0.1 26.0 27 3 3 30 30 30 0 Homeobox associated leucine zipper Sec63 PF02889.16 OWF53684.1 - 8.1e-47 159.5 1.8 1.6e-46 158.6 1.8 1.6 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OWF53684.1 - 4.2e-24 85.3 0.0 1e-23 84.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OWF53684.1 - 3.7e-10 40.1 0.0 1.2e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OWF53684.1 - 1.7e-09 38.0 0.0 2.2e-08 34.4 0.0 3.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OWF53684.1 - 0.027 14.7 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.6 OWF53684.1 - 0.05 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain GTP_EFTU PF00009.27 OWF53685.1 - 2e-28 99.2 0.3 3.4e-28 98.5 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF53685.1 - 2.8e-07 30.6 0.1 5.4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OWF53685.1 - 8.5e-05 22.1 1.4 0.0013 18.2 1.4 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 OWF53685.1 - 0.0027 18.1 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.19 OWF53685.1 - 0.0052 16.4 1.4 0.0072 15.9 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OWF53685.1 - 0.0071 16.1 1.5 3.3 7.4 0.0 2.7 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OWF53685.1 - 0.011 15.1 0.3 0.05 12.9 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RIBIOP_C PF04950.12 OWF53685.1 - 0.046 13.1 0.1 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Arf PF00025.21 OWF53685.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF53685.1 - 1.2 9.0 6.0 0.31 10.9 0.2 2.6 3 0 0 3 3 3 0 RsgA GTPase SNF PF00209.18 OWF53686.1 - 2.1e-29 102.6 11.4 2.4e-29 102.4 11.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4792 PF16040.5 OWF53687.1 - 5.2e-05 23.1 6.1 0.16 11.9 0.1 5.0 1 1 3 4 4 4 1 Domain of unknown function (DUF4792) Rep_fac-A_3 PF08661.11 OWF53687.1 - 0.00011 22.5 4.1 5.1 7.5 0.1 4.0 1 1 4 5 5 5 2 Replication factor A protein 3 Pentapeptide_4 PF13599.6 OWF53687.1 - 0.003 17.7 1.0 1.6 8.9 0.2 2.6 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) VEG PF06257.11 OWF53687.1 - 0.006 16.6 3.0 6.6 6.9 0.2 4.4 2 2 4 6 6 6 1 Biofilm formation stimulator VEG DUF4314 PF14192.6 OWF53687.1 - 0.015 15.2 2.0 0.048 13.6 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4314) DUF3947 PF13135.6 OWF53687.1 - 0.016 15.4 1.9 18 5.6 0.1 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3947) DUF2807 PF10988.8 OWF53687.1 - 0.031 14.1 5.6 0.11 12.3 0.4 2.0 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Apocytochr_F_C PF01333.19 OWF53687.1 - 0.037 14.1 2.4 2.4 8.2 0.2 2.8 1 1 1 2 2 2 0 Apocytochrome F, C-terminal CathepsinC_exc PF08773.11 OWF53687.1 - 0.074 13.3 2.0 6.1 7.1 0.8 2.6 1 1 1 2 2 2 0 Cathepsin C exclusion domain DUF4853 PF16145.5 OWF53687.1 - 0.26 11.4 4.7 0.24 11.5 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4853) Glyco_tran_10_N PF17039.5 OWF53687.1 - 0.82 10.1 11.2 8.1 6.9 0.8 3.4 2 2 1 3 3 3 0 Fucosyltransferase, N-terminal DUF4902 PF16245.5 OWF53687.1 - 1 9.3 5.0 1.3 8.9 0.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4902) PrgU PF09627.10 OWF53687.1 - 1.6 8.7 7.7 2.7 8.0 1.2 3.3 1 1 2 3 3 3 0 PrgU-like protein HCV_NS5a_C PF12941.7 OWF53688.1 - 0.97 9.2 6.7 20 4.9 0.1 4.5 1 1 2 5 5 5 0 HCV NS5a protein C-terminal region HLH PF00010.26 OWF53689.1 - 4e-14 52.3 0.1 7.1e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3246 PF11596.8 OWF53689.1 - 0.24 10.8 2.4 0.38 10.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CCDC106 PF15794.5 OWF53689.1 - 1.9 8.1 8.2 3.8 7.2 8.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 OWF53689.1 - 8.3 4.6 8.3 11 4.1 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-H2C2_2 PF13465.6 OWF53690.1 - 8.6e-33 111.3 94.5 1.1e-08 35.2 1.4 11.4 11 1 0 11 11 11 7 Zinc-finger double domain zf-C2H2 PF00096.26 OWF53690.1 - 1.4e-23 81.9 105.7 7.1e-05 23.1 1.3 11.3 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OWF53690.1 - 5.7e-18 64.4 85.7 5.9e-05 22.7 1.5 10.3 10 0 0 10 10 10 8 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OWF53690.1 - 4.3e-12 45.8 98.8 0.0025 18.5 0.7 11.7 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF53690.1 - 3.9e-05 23.8 36.1 0.71 10.2 1.4 8.9 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding Fibrinogen_BP PF08017.11 OWF53690.1 - 0.011 14.2 0.3 0.025 13.0 0.3 1.5 1 0 0 1 1 1 0 Fibrinogen binding protein zf_C2H2_ZHX PF18387.1 OWF53690.1 - 0.02 14.5 0.2 0.02 14.5 0.2 8.4 4 1 4 9 9 9 0 Zinc-fingers and homeoboxes C2H2 finger domain RRM_1 PF00076.22 OWF53691.1 - 5e-10 39.1 0.0 7.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 OWF53691.1 - 0.031 14.6 1.7 7.9 6.9 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2303 PF10065.9 OWF53691.1 - 0.033 13.4 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) RRM_5 PF13893.6 OWF53691.1 - 0.062 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.8 OWF53691.1 - 0.1 12.9 3.0 3.7 7.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OWF53691.1 - 0.11 13.0 3.8 8.8 7.0 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type PhnA_Zn_Ribbon PF08274.12 OWF53691.1 - 0.12 12.3 0.2 6.3 6.8 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-met PF12874.7 OWF53691.1 - 0.23 11.9 2.1 1.4 9.5 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF53691.1 - 1.5 8.9 5.6 0.31 11.1 1.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Beta-TrCP_D PF12125.8 OWF53692.1 - 1.1 9.2 6.3 1.1e+02 2.8 0.2 5.2 4 2 2 6 6 6 0 D domain of beta-TrCP zf-RING_UBOX PF13445.6 OWF53693.1 - 9.9e-11 41.5 5.5 9.9e-11 41.5 5.5 4.1 4 1 1 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF53693.1 - 3.1e-08 33.3 8.0 3.1e-08 33.3 8.0 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF53693.1 - 4.9e-08 33.0 7.2 4.9e-08 33.0 7.2 3.7 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF53693.1 - 6.3e-08 32.8 6.8 6.3e-08 32.8 6.8 3.8 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OWF53693.1 - 2.4e-06 27.4 5.8 2.4e-06 27.4 5.8 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF53693.1 - 1.1e-05 25.2 11.1 1.1e-05 25.2 11.1 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF53693.1 - 1.9e-05 24.4 5.3 1.9e-05 24.4 5.3 4.2 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF53693.1 - 0.00031 20.8 11.4 0.00031 20.8 11.4 4.6 5 1 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF53694.1 - 1.9e-09 37.4 10.0 1.9e-09 37.4 10.0 2.5 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF53694.1 - 1.5e-07 31.1 10.9 1.5e-07 31.1 10.9 3.5 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF53694.1 - 7.4e-07 29.2 11.8 7.4e-07 29.2 11.8 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF53694.1 - 2.1e-06 27.9 10.0 2.1e-06 27.9 10.0 3.4 3 0 0 3 3 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF53694.1 - 4.1e-06 26.7 9.6 4.1e-06 26.7 9.6 3.3 3 1 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF53694.1 - 2.6e-05 24.0 13.1 2.6e-05 24.0 13.1 3.7 3 2 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF53694.1 - 5.1e-05 23.0 9.1 5.1e-05 23.0 9.1 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 OWF53694.1 - 0.00068 19.3 0.4 0.0028 17.3 0.4 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 OWF53694.1 - 0.001 19.1 9.3 0.001 19.1 9.3 4.5 4 1 0 4 4 4 2 B-box zinc finger NHL PF01436.21 OWF53694.1 - 0.0011 18.8 5.5 2.2 8.5 0.0 4.6 4 0 0 4 4 4 1 NHL repeat FAM184 PF15665.5 OWF53694.1 - 0.028 14.2 5.5 0.056 13.2 5.5 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B SBBP PF06739.11 OWF53694.1 - 0.081 12.9 0.1 0.28 11.2 0.1 1.9 1 0 0 1 1 1 0 Beta-propeller repeat Apolipoprotein PF01442.18 OWF53694.1 - 0.085 12.7 5.1 0.27 11.1 5.1 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain SbsC_C PF18058.1 OWF53694.1 - 0.1 12.8 1.8 1.5 9.1 0.1 2.5 1 1 1 2 2 2 0 SbsC C-terminal domain Baculo_PEP_C PF04513.12 OWF53694.1 - 0.1 12.6 4.7 0.31 11.1 3.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1722 PF08349.11 OWF53694.1 - 0.14 12.5 0.8 0.4 11.0 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) CspB_prodomain PF18425.1 OWF53694.1 - 0.18 11.8 1.6 0.99 9.5 0.1 2.4 1 1 1 2 2 2 0 Csp protease B prodomain zf-RING_6 PF14835.6 OWF53694.1 - 0.99 9.3 14.8 6.9 6.6 1.1 3.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DUF1664 PF07889.12 OWF53694.1 - 3.5 7.7 8.3 19 5.3 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 OWF53694.1 - 3.7 6.8 9.8 2.2 7.5 7.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PC4 PF02229.16 OWF53695.1 - 4.7e-12 45.4 0.0 3.3e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) DUF4894 PF16235.5 OWF53695.1 - 0.18 12.1 0.1 0.99 9.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4894) T3SchapCesA PF11439.8 OWF53696.1 - 0.32 11.2 8.3 2.1e+02 2.1 0.0 5.8 3 2 6 9 9 9 0 Type III secretion system filament chaperone CesA JTB PF05439.12 OWF53696.1 - 2.3 8.3 24.0 74 3.4 12.5 3.3 1 1 1 2 2 2 0 Jumping translocation breakpoint protein (JTB) IL17 PF06083.11 OWF53697.1 - 1.5e-18 67.0 3.8 2.3e-18 66.5 3.8 1.3 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 OWF53700.1 - 3e-14 53.2 5.2 5.4e-14 52.4 5.2 1.4 1 0 0 1 1 1 1 Interleukin-17 DUF4735 PF15882.5 OWF53700.1 - 0.2 11.1 1.6 0.54 9.7 0.7 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4735) Fibrinogen_BP PF08017.11 OWF53701.1 - 4.4e-46 157.1 27.9 5.1e-26 91.0 11.2 2.1 1 1 1 2 2 2 2 Fibrinogen binding protein TT_ORF2a PF08197.11 OWF53701.1 - 8.7e-08 32.1 37.5 9.3 6.3 0.0 13.2 1 1 9 12 12 12 7 pORF2a truncated protein SPECT1 PF18680.1 OWF53701.1 - 1.5 8.5 3.2 27 4.4 0.1 3.6 2 2 3 5 5 5 0 Plasmodium host cell traversal SPECT1 Ion_trans PF00520.31 OWF53702.1 - 9.3e-29 100.4 21.9 9.3e-29 100.4 21.9 1.4 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.22 OWF53702.1 - 2.4e-20 72.6 0.3 5.1e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF53702.1 - 1.1e-09 38.1 7.7 1.1e-09 38.1 7.7 2.6 2 0 0 2 2 2 1 Ion channel DUF3185 PF11381.8 OWF53702.1 - 0.095 12.7 1.5 0.15 12.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Polysacc_synt PF01943.17 OWF53703.1 - 0.00099 18.6 1.5 0.002 17.6 1.5 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GtrA PF04138.14 OWF53703.1 - 0.04 14.2 0.6 0.14 12.4 0.6 1.9 1 0 0 1 1 1 0 GtrA-like protein Ion_trans PF00520.31 OWF53704.1 - 1.3e-34 119.5 17.4 2.2e-34 118.8 17.4 1.4 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF53704.1 - 1.1e-23 83.3 0.0 2.7e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF53704.1 - 2.6e-09 36.9 9.9 2.6e-09 36.9 9.9 2.2 3 0 0 3 3 3 1 Ion channel DUF2650 PF10853.8 OWF53704.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2650) WD40 PF00400.32 OWF53705.1 - 6.1e-12 45.9 1.3 6.6e-05 23.6 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat LRR_4 PF12799.7 OWF53705.1 - 6.8e-12 45.4 19.9 5.7e-07 29.8 3.9 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF53705.1 - 2e-11 43.5 4.7 1e-08 34.8 4.3 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 OWF53705.1 - 0.016 14.7 1.3 0.11 12.0 1.2 2.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 OWF53705.1 - 0.03 14.4 9.0 1.4 9.1 0.7 4.7 5 0 0 5 5 5 0 Leucine Rich repeat DUF2501 PF10696.9 OWF53705.1 - 0.04 14.2 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) DUF1007 PF06226.13 OWF53705.1 - 0.078 12.9 0.7 4.3 7.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1007) LRR_1 PF00560.33 OWF53705.1 - 0.13 12.9 6.1 5.2 8.0 2.6 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat Nucleos_tra2_C PF07662.13 OWF53706.1 - 7e-70 235.1 4.3 7e-70 235.1 4.3 2.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF53706.1 - 6.5e-23 81.1 1.3 6.5e-23 81.1 1.3 3.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OWF53706.1 - 5.7e-05 23.4 7.8 5.7e-05 23.4 7.8 3.4 4 1 1 5 5 5 1 Nucleoside recognition Nucleos_tra2_C PF07662.13 OWF53707.1 - 1.5e-68 230.7 4.9 1.5e-68 230.7 4.9 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OWF53707.1 - 5.5e-21 74.9 1.1 5.5e-21 74.9 1.1 3.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OWF53707.1 - 2.5e-05 24.5 7.0 2.5e-05 24.5 7.0 3.2 5 0 0 5 5 5 1 Nucleoside recognition Rota_NSP4 PF01452.16 OWF53707.1 - 0.1 12.3 0.4 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Rotavirus non structural protein Hira PF07569.11 OWF53709.1 - 7.8e-46 156.6 0.2 2.3e-45 155.1 0.2 1.9 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 OWF53709.1 - 1.7e-33 114.1 29.1 1.7e-07 31.8 2.3 9.9 9 1 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF53709.1 - 1.2e-12 48.0 5.4 0.42 10.9 0.0 6.7 3 1 3 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OWF53709.1 - 0.0001 22.0 0.3 0.00026 20.8 0.3 1.7 1 0 0 1 1 1 1 HIRA B motif RAB3GAP2_N PF14655.6 OWF53709.1 - 0.0059 15.9 0.1 0.0059 15.9 0.1 2.1 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus 7TM_GPCR_Srw PF10324.9 OWF53710.1 - 1.1e-14 54.4 27.6 2e-14 53.6 27.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF53710.1 - 1.1e-07 31.4 26.5 1.7e-07 30.9 26.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC_membrane PF00664.23 OWF53711.1 - 1.7e-61 208.3 36.2 2.3e-37 129.2 13.1 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF53711.1 - 1.6e-50 171.2 0.0 2.5e-27 96.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF53711.1 - 2.1e-10 40.4 6.3 0.015 14.8 0.1 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OWF53711.1 - 5e-08 33.1 3.3 0.014 15.2 0.1 4.3 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF53711.1 - 1.5e-06 28.8 0.3 0.0023 18.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OWF53711.1 - 0.00021 21.6 1.3 0.97 9.7 0.1 3.1 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OWF53711.1 - 0.00024 21.2 0.3 1.2 9.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF53711.1 - 0.00037 20.5 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OWF53711.1 - 0.00079 19.5 1.0 0.1 12.6 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 OWF53711.1 - 0.00096 19.6 0.1 0.2 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 OWF53711.1 - 0.0012 17.9 0.1 0.26 10.3 0.1 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 OWF53711.1 - 0.0017 18.0 0.0 0.24 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OWF53711.1 - 0.0032 17.2 3.5 22 4.7 0.1 4.5 5 0 0 5 5 4 0 IstB-like ATP binding protein AAA_29 PF13555.6 OWF53711.1 - 0.0037 17.0 8.9 0.039 13.7 0.3 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain cobW PF02492.19 OWF53711.1 - 0.008 15.8 3.2 0.077 12.6 0.9 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 OWF53711.1 - 0.0085 15.8 3.3 0.073 12.8 0.7 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_13 PF13166.6 OWF53711.1 - 0.016 13.9 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 OWF53711.1 - 0.018 13.9 3.6 5.1 5.8 0.1 3.5 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 OWF53711.1 - 0.025 13.8 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 OWF53711.1 - 0.037 14.4 0.0 1.9 8.9 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbtB PF09489.10 OWF53711.1 - 0.077 13.1 0.4 0.38 10.9 0.4 2.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) AAA_18 PF13238.6 OWF53711.1 - 0.077 13.5 0.1 31 5.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF53711.1 - 0.1 12.1 0.5 6.5 6.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OWF53711.1 - 0.15 11.8 0.3 1.3 8.7 0.1 2.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 OWF53711.1 - 0.17 11.6 0.0 24 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OWF53711.1 - 0.19 12.0 1.6 25 5.1 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 OWF53711.1 - 0.2 10.8 0.6 9.5 5.3 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 OWF53711.1 - 0.21 10.8 0.4 9.1 5.4 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.12 OWF53711.1 - 0.37 10.2 3.2 2.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.12 OWF53711.1 - 0.42 10.5 1.8 5.8 6.8 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 OWF53711.1 - 1.8 8.3 4.2 1.1 8.9 0.0 2.7 4 0 0 4 4 4 0 AAA domain Spt4 PF06093.13 OWF53712.1 - 5e-33 113.0 1.0 6e-33 112.8 1.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Pkinase PF00069.25 OWF53713.1 - 1.3e-66 224.7 0.4 2.1e-66 224.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF53713.1 - 1.4e-30 106.5 0.0 2.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF53713.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF53713.1 - 0.042 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Ribosomal_L18p PF00861.22 OWF53714.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast WD40 PF00400.32 OWF53715.1 - 8.6e-64 210.0 34.2 1e-08 35.7 0.1 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF53715.1 - 2e-25 88.9 2.9 5e-05 23.5 0.0 6.1 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 OWF53715.1 - 5.1e-13 49.3 0.2 9e-13 48.6 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 OWF53715.1 - 2.7e-09 36.4 0.5 0.0011 18.1 0.0 4.6 3 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF53715.1 - 1.2e-07 31.8 0.0 0.0028 17.5 0.0 3.4 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OWF53715.1 - 2.4e-05 23.2 2.6 5.5 5.5 0.1 4.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OWF53715.1 - 3.3e-05 23.4 0.0 0.39 10.0 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain PD40 PF07676.12 OWF53715.1 - 0.00038 20.3 2.2 1.9 8.5 0.0 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 OWF53715.1 - 0.0018 18.2 0.2 1.8 8.5 0.0 3.7 4 0 0 4 4 4 1 Nitrous oxide reductase propeller repeat Frtz PF11768.8 OWF53715.1 - 0.0025 16.2 0.0 0.45 8.8 0.0 2.9 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 OWF53715.1 - 0.14 11.0 4.5 1.3 7.8 0.2 3.1 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain HC2 PF07382.11 OWF53717.1 - 0.00028 21.0 0.0 0.00035 20.7 0.0 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF1930 PF09122.10 OWF53717.1 - 0.012 15.6 10.3 4.3 7.4 0.5 4.2 1 1 4 5 5 5 0 Domain of unknown function (DUF1930) TPR_4 PF07721.14 OWF53717.1 - 2.7 8.9 16.0 48 5.0 0.2 6.2 3 2 4 8 8 8 0 Tetratricopeptide repeat Herpes_UL20 PF04544.12 OWF53719.1 - 0.13 12.6 33.0 60 3.9 0.7 9.9 1 1 10 11 11 11 0 Herpesvirus egress protein UL20 ZNRF_3_ecto PF18212.1 OWF53720.1 - 3.2e-28 97.8 0.0 7.4e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 OWF53720.1 - 5.7e-13 49.0 5.7 5.7e-13 49.0 5.7 4.7 5 1 1 6 6 6 1 Ring finger domain zf-RING_11 PF17123.5 OWF53720.1 - 5.6e-11 42.0 1.1 5.6e-11 42.0 1.1 3.5 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF53720.1 - 9.4e-09 35.0 5.4 9.4e-09 35.0 5.4 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF53720.1 - 1.4e-07 31.2 4.5 1.4e-07 31.2 4.5 4.5 7 0 0 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF53720.1 - 1.8e-06 28.1 6.8 1.8e-06 28.1 6.8 4.0 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF53720.1 - 2.3e-05 24.3 4.1 2.3e-05 24.3 4.1 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF53720.1 - 0.001 19.0 2.8 0.001 19.0 2.8 4.5 5 0 0 5 5 5 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF53720.1 - 6.1 7.0 10.1 0.56 10.3 2.6 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glyco_hydro_63 PF03200.16 OWF53721.1 - 0.022 13.5 2.2 1.8 7.3 0.3 2.6 2 1 0 2 2 2 0 Glycosyl hydrolase family 63 C-terminal domain Mab-21 PF03281.14 OWF53722.1 - 2.6e-12 46.6 0.3 4.8e-12 45.8 0.3 1.4 1 0 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.14 OWF53723.1 - 2.5e-19 69.7 0.0 3.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Mab-21 protein PRO8NT PF08082.11 OWF53723.1 - 0.042 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain PNISR PF15996.5 OWF53723.1 - 0.74 10.1 3.3 0.26 11.6 0.3 1.7 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Tmem26 PF09772.9 OWF53724.1 - 1.1e-69 235.0 13.0 5.9e-47 160.4 2.2 2.1 1 1 1 2 2 2 2 Transmembrane protein 26 Na_Ca_ex PF01699.24 OWF53725.1 - 3.1e-42 144.1 31.3 7.8e-24 84.4 10.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 OWF53725.1 - 6e-36 122.6 1.2 2.3e-17 63.0 0.0 2.8 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex_C PF16494.5 OWF53725.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Death PF00531.22 OWF53726.1 - 1.6e-06 28.2 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Death domain Tuberin PF03542.16 OWF53727.1 - 2.9e-130 434.5 7.0 2.9e-130 434.5 7.0 1.7 2 0 0 2 2 2 1 Tuberin DUF3384 PF11864.8 OWF53727.1 - 6.5e-89 299.0 3.4 1.4e-88 297.9 3.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 OWF53727.1 - 1.9e-45 154.7 0.0 3.4e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP HEAT PF02985.22 OWF53727.1 - 0.024 14.9 0.7 0.44 10.9 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat zf_CCCH_5 PF18384.1 OWF53728.1 - 1.3e-20 73.2 13.9 1.3e-20 73.2 13.9 2.8 2 0 0 2 2 2 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 OWF53728.1 - 1.9e-06 27.7 6.4 2.1e-05 24.3 1.0 6.4 8 0 0 8 8 8 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OWF53728.1 - 3.3e-05 23.8 24.4 0.037 14.1 0.3 5.9 5 0 0 5 5 5 3 Zinc finger domain Histone PF00125.24 OWF53729.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OWF53729.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OWF53729.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 OWF53729.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OWF53729.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CCSMST1 PF15013.6 OWF53730.1 - 2e-12 47.1 0.1 3.8e-12 46.2 0.0 1.5 2 0 0 2 2 2 1 CCSMST1 family Macin PF14865.6 OWF53730.1 - 0.15 12.6 3.0 0.28 11.7 3.0 1.4 1 0 0 1 1 1 0 Macin DUF4573 PF15140.6 OWF53731.1 - 5.4e-08 32.8 1.7 3.7e-07 30.1 1.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) Stn1_C PF12659.7 OWF53731.1 - 0.017 15.0 2.6 0.046 13.7 2.6 1.7 1 1 0 1 1 1 0 Telomere capping C-terminal wHTH DUF2345 PF10106.9 OWF53731.1 - 0.038 13.8 2.6 0.057 13.3 2.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) VapB_antitoxin PF09957.9 OWF53731.1 - 0.064 13.2 4.0 30 4.6 0.1 3.9 1 1 4 5 5 5 0 Bacterial antitoxin of type II TA system, VapB GMP_PDE_delta PF05351.11 OWF53731.1 - 0.08 13.0 0.5 0.2 11.7 0.5 1.7 1 1 0 1 1 1 0 GMP-PDE, delta subunit cNMP_binding PF00027.29 OWF53732.1 - 2.7e-41 139.5 0.3 1.1e-19 70.3 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OWF53732.1 - 1.8e-12 46.7 0.3 3.7e-12 45.7 0.3 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Radial_spoke PF04712.12 OWF53732.1 - 0.031 13.2 1.5 0.043 12.8 1.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF5586 PF17824.1 OWF53732.1 - 0.035 13.2 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) Dpy-30 PF05186.13 OWF53732.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Dpy-30 motif SAC3_GANP PF03399.16 OWF53733.1 - 8e-26 91.1 2.9 3.2e-24 85.9 2.9 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OWF53733.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Ribosomal_S2 PF00318.20 OWF53735.1 - 1e-25 90.2 0.0 3.5e-14 52.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OWF53735.1 - 5.2e-14 53.4 23.1 1.4e-13 52.0 23.1 1.8 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus LRR_3 PF07725.12 OWF53736.1 - 0.065 13.1 0.0 2.9e+02 1.5 0.0 6.3 14 0 0 14 14 14 0 Leucine Rich Repeat DUF402 PF04167.13 OWF53736.1 - 0.15 12.3 0.2 1.3e+02 2.8 0.1 5.6 1 1 2 3 3 3 0 Protein of unknown function (DUF402) DGF-1_C PF11040.8 OWF53736.1 - 0.15 12.1 28.9 1.9e+02 2.1 0.0 11.6 1 1 13 14 14 14 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SapB_1 PF05184.15 OWF53737.1 - 2.1e-43 145.9 47.1 2.1e-09 37.2 1.7 8.7 8 0 0 8 8 8 7 Saposin-like type B, region 1 SapB_2 PF03489.17 OWF53737.1 - 4.9e-35 119.3 33.7 7.5e-13 48.3 0.1 7.7 7 0 0 7 7 7 5 Saposin-like type B, region 2 Requiem_N PF14051.6 OWF53737.1 - 1.8e-27 95.3 0.4 4e-27 94.2 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. SapA PF02199.15 OWF53737.1 - 2.7e-20 72.4 28.1 6.5e-14 51.9 7.7 4.4 4 0 0 4 4 4 2 Saposin A-type domain PHD PF00628.29 OWF53737.1 - 4e-16 58.6 15.1 4.6e-10 39.2 1.2 6.1 6 1 1 7 7 7 2 PHD-finger PHD_4 PF16866.5 OWF53737.1 - 0.003 17.6 6.7 0.003 17.6 6.7 6.5 8 1 1 9 9 9 1 PHD-finger HCV_capsid PF01543.17 OWF53737.1 - 0.15 12.3 0.0 0.54 10.5 0.0 1.9 1 0 0 1 1 1 0 Hepatitis C virus capsid protein TPR_2 PF07719.17 OWF53738.1 - 2e-15 55.6 15.5 0.091 12.9 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 OWF53738.1 - 1.6e-13 49.8 13.4 0.015 15.1 0.1 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF53738.1 - 7.5e-12 45.4 9.7 0.042 14.2 0.0 8.2 6 3 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 OWF53738.1 - 5.9e-10 39.5 11.4 0.0096 16.4 0.5 6.8 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF53738.1 - 5e-08 32.4 9.0 0.12 12.5 0.0 8.0 10 0 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF53738.1 - 6e-07 29.6 20.8 0.0065 16.7 7.2 6.4 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OWF53738.1 - 7.9e-07 28.8 16.4 0.16 12.2 0.0 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF53738.1 - 0.0012 18.7 1.6 37 4.4 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF285 PF03382.14 OWF53738.1 - 0.0035 17.1 0.4 0.0081 15.9 0.4 1.6 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 HrpB1_HrpK PF09613.10 OWF53738.1 - 0.0054 16.4 3.0 0.12 12.1 0.1 3.9 4 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 OWF53738.1 - 0.012 16.3 1.6 39 5.0 0.1 5.2 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF53738.1 - 0.015 15.9 13.2 1.7 9.4 0.0 6.8 8 1 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF53738.1 - 0.024 14.7 8.8 0.77 9.9 0.1 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat BEX PF04538.12 OWF53738.1 - 0.04 14.5 0.1 0.04 14.5 0.1 2.1 2 0 0 2 2 1 0 Brain expressed X-linked like family SMBP PF16785.5 OWF53738.1 - 0.2 11.9 0.9 3.3 8.0 0.1 3.0 3 0 0 3 3 3 0 Small metal-binding protein LMBR1 PF04791.16 OWF53738.1 - 0.27 10.1 2.3 0.44 9.4 2.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein YqzH PF14164.6 OWF53738.1 - 0.32 11.1 4.1 3.2 7.9 0.5 3.1 3 0 0 3 3 3 0 YqzH-like protein TPR_11 PF13414.6 OWF53738.1 - 0.74 9.5 9.9 23 4.8 0.0 5.5 6 0 0 6 6 6 0 TPR repeat zf-CCHC PF00098.23 OWF53739.1 - 6.6e-08 32.3 44.0 5e-05 23.2 2.8 5.5 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 OWF53739.1 - 0.0041 16.9 2.5 0.0041 16.9 2.5 4.9 5 0 0 5 5 5 3 Zinc knuckle zf-WRNIP1_ubi PF18279.1 OWF53740.1 - 0.0011 19.5 21.2 33 5.4 0.1 7.4 7 0 0 7 7 7 5 Werner helicase-interacting protein 1 ubiquitin-binding domain ATE_N PF04376.13 OWF53740.1 - 0.025 15.0 7.0 95 3.5 0.0 5.7 6 0 0 6 6 6 0 Arginine-tRNA-protein transferase, N terminus Gemini_AC4_5 PF04807.12 OWF53740.1 - 3.2 7.5 28.0 9 6.1 0.2 7.2 7 0 0 7 7 7 0 Geminivirus AC4/5 conserved region Peptidase_A2E PF12382.8 OWF53741.1 - 0.00021 21.3 3.6 0.56 10.2 0.2 3.0 1 1 2 3 3 3 3 Retrotransposon peptidase DUF2118 PF09891.9 OWF53741.1 - 0.00082 19.4 0.0 1.1 9.3 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2118) WAK PF08488.11 OWF53741.1 - 0.0011 19.4 8.0 5.1 7.7 1.9 4.5 1 1 2 3 3 3 2 Wall-associated kinase DUF3261 PF11659.8 OWF53741.1 - 0.0025 17.7 0.0 2.4 8.0 0.0 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF3261) DUF1495 PF07381.11 OWF53741.1 - 0.0037 17.1 0.0 20 5.1 0.0 3.8 3 2 1 4 4 4 0 Winged helix DNA-binding domain (DUF1495) Keratin_B2 PF01500.17 OWF53741.1 - 0.083 12.9 13.1 1.3 9.0 3.2 2.0 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein BAT PF15915.5 OWF53741.1 - 0.12 12.2 7.6 1.4 8.8 1.2 2.1 1 1 1 2 2 2 0 GAF and HTH_10 associated domain Root_cap PF06830.11 OWF53741.1 - 0.56 10.4 2.1 13 6.0 0.0 3.5 2 1 1 5 5 5 0 Root cap DUF1505 PF07403.11 OWF53741.1 - 0.67 10.2 9.8 4.7 7.4 3.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1505) DUF1826 PF08856.11 OWF53741.1 - 0.69 9.8 5.0 11 5.9 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1826) Methyltransf_29 PF03141.16 OWF53741.1 - 4.9 5.6 5.9 27 3.1 0.3 3.0 1 1 2 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhomboid PF01694.22 OWF53742.1 - 8.6e-32 110.2 12.1 8.6e-32 110.2 12.1 1.9 2 0 0 2 2 2 1 Rhomboid family Rhomboid_SP PF12595.8 OWF53742.1 - 0.00034 20.1 0.4 0.00034 20.1 0.4 1.7 2 0 0 2 2 2 1 Rhomboid serine protease Fringe PF02434.16 OWF53743.1 - 1.1e-11 44.7 0.3 6.4e-11 42.2 0.3 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF53743.1 - 2.3e-07 30.8 0.3 0.00081 19.3 0.0 2.9 2 1 1 3 3 3 2 Galactosyltransferase zf-C2H2 PF00096.26 OWF53744.1 - 4.7e-08 33.1 24.8 0.015 15.7 7.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF53744.1 - 5e-08 33.1 21.1 0.034 15.0 1.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OWF53744.1 - 0.00026 21.3 15.9 0.42 11.0 0.1 3.9 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OWF53744.1 - 0.00095 19.1 22.6 0.029 14.4 2.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OWF53744.1 - 0.029 15.1 6.5 1.5 9.5 0.2 3.2 2 2 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 OWF53744.1 - 0.029 14.8 3.2 0.029 14.8 3.2 4.4 5 0 0 5 5 5 0 Zinc-finger double domain CpXC PF14353.6 OWF53744.1 - 0.03 14.4 5.6 1.5 8.9 1.4 3.3 3 1 0 3 3 3 0 CpXC protein zf-BED PF02892.15 OWF53744.1 - 0.053 13.5 14.7 0.16 12.0 2.0 3.7 3 0 0 3 3 3 0 BED zinc finger OS-D PF03392.13 OWF53744.1 - 0.056 13.6 0.4 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Zn-ribbon_8 PF09723.10 OWF53744.1 - 0.11 12.6 7.7 9.3 6.5 0.9 3.5 2 1 0 2 2 2 0 Zinc ribbon domain PyrI_C PF02748.15 OWF53744.1 - 1.2 9.1 8.4 3.8 7.5 0.2 2.8 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SAM35 PF10806.8 OWF53745.1 - 1 9.6 31.5 14 6.0 0.4 6.9 1 1 5 7 7 7 0 SAM35, subunit of SAM coomplex DUF2963 PF11178.8 OWF53745.1 - 1.6 8.5 9.8 24 4.7 0.1 6.5 6 1 1 7 7 7 0 Protein of unknown function (DUF2963) Leader_Trp PF08255.11 OWF53745.1 - 3.6 7.8 17.1 2.1e+02 2.4 0.0 10.3 10 0 0 10 10 10 0 Trp-operon Leader Peptide Ca_chan_IQ PF08763.11 OWF53746.1 - 0.0005 20.2 4.1 6.4 7.1 0.1 4.1 1 1 2 3 3 3 3 Voltage gated calcium channel IQ domain PBS_linker_poly PF00427.21 OWF53746.1 - 0.0079 16.2 2.9 4 7.5 0.6 3.2 1 1 1 2 2 2 2 Phycobilisome Linker polypeptide Ca_chan_IQ PF08763.11 OWF53747.1 - 0.00015 21.9 3.8 5.4 7.3 0.3 4.5 1 1 3 4 4 4 4 Voltage gated calcium channel IQ domain PSD1 PF07587.11 OWF53747.1 - 0.099 12.1 4.1 24 4.3 0.1 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1553) CCAP PF11105.8 OWF53747.1 - 0.18 11.8 2.7 2.6 8.0 0.4 2.6 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a MATH PF00917.26 OWF53748.1 - 2.5e-05 24.4 17.2 2.8 8.1 0.1 7.1 1 1 5 7 7 7 6 MATH domain DUF4369 PF14289.6 OWF53748.1 - 0.00016 22.1 20.6 8.5 7.0 0.2 7.5 1 1 4 5 5 5 5 Domain of unknown function (DUF4369) MATH PF00917.26 OWF53749.1 - 0.00019 21.6 24.0 6.7 6.9 0.1 9.5 1 1 10 11 11 11 7 MATH domain Pkinase PF00069.25 OWF53750.1 - 1.3e-63 214.9 0.0 2.1e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 OWF53750.1 - 2.3e-57 191.4 17.7 6.7e-11 42.6 0.0 7.7 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 OWF53750.1 - 5e-39 134.1 0.0 1.1e-38 133.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 OWF53750.1 - 1.2e-31 107.8 22.8 1.3e-06 28.0 0.6 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 OWF53750.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF53750.1 - 0.0064 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_GP20 PF06810.11 OWF53750.1 - 0.01 15.7 4.9 0.023 14.5 4.9 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 Pkinase_fungal PF17667.1 OWF53750.1 - 0.015 14.1 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FAM76 PF16046.5 OWF53750.1 - 1.3 8.3 10.2 2.5 7.4 10.2 1.3 1 0 0 1 1 1 0 FAM76 protein DUF3450 PF11932.8 OWF53750.1 - 2.1 7.6 9.5 4.3 6.6 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Hydrolase_4 PF12146.8 OWF53751.1 - 4e-18 65.6 0.0 2.2e-12 46.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OWF53751.1 - 5.4e-13 49.2 0.2 8.8e-11 41.9 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OWF53751.1 - 1.7e-10 41.9 0.0 4.5e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OWF53751.1 - 1.9e-07 31.1 0.0 2.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OWF53751.1 - 0.00019 21.3 0.0 0.051 13.4 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Thioesterase PF00975.20 OWF53751.1 - 0.00092 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 OWF53751.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 OWF53751.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1223 PF06764.11 OWF53751.1 - 0.21 11.6 0.1 0.39 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) BAH PF01426.18 OWF53752.1 - 3.4e-09 36.6 0.2 1.3e-08 34.8 0.2 2.0 1 1 0 1 1 1 1 BAH domain Sec10 PF07393.11 OWF53753.1 - 5.9e-133 444.8 10.0 7.3e-130 434.6 10.0 2.9 1 1 0 1 1 1 1 Exocyst complex component Sec10 TMF_DNA_bd PF12329.8 OWF53753.1 - 0.078 13.0 5.3 0.39 10.7 5.4 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding VGPC1_C PF16799.5 OWF53753.1 - 0.11 12.4 2.0 0.39 10.7 2.0 1.9 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Ax_dynein_light PF10211.9 OWF53753.1 - 0.14 12.1 7.6 0.049 13.6 4.2 1.9 2 0 0 2 2 2 0 Axonemal dynein light chain DUF1664 PF07889.12 OWF53753.1 - 0.21 11.6 5.1 1.7 8.7 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 OWF53753.1 - 0.25 11.5 8.6 0.026 14.8 2.2 2.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 OWF53753.1 - 0.28 11.3 7.1 1.5 9.0 7.0 2.1 1 1 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.20 OWF53753.1 - 4.2 7.4 15.2 0.31 11.0 3.8 4.2 4 2 1 5 5 5 0 Prefoldin subunit HAT_KAT11 PF08214.11 OWF53754.1 - 0.013 14.8 0.7 0.013 14.8 0.7 2.1 2 0 0 2 2 2 0 Histone acetylation protein SR-25 PF10500.9 OWF53754.1 - 0.45 10.1 27.4 0.02 14.5 14.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpc4 PF05132.14 OWF53754.1 - 0.59 10.6 17.8 0.082 13.3 5.4 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 FERM_M PF00373.18 OWF53755.1 - 2.7e-21 76.1 1.1 5.2e-21 75.3 0.4 1.8 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 OWF53755.1 - 7.8e-17 61.5 0.1 1.8e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 OWF53755.1 - 1.7e-11 43.9 0.3 3.3e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 FERM N-terminal domain DUF2428 PF10350.9 OWF53756.1 - 1.5e-50 172.0 1.4 4e-50 170.6 1.4 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) BPL_LplA_LipB_2 PF16917.5 OWF53756.1 - 0.017 14.7 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family HEAT PF02985.22 OWF53756.1 - 0.056 13.7 4.5 40 4.8 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat Rx_N PF18052.1 OWF53756.1 - 0.062 13.6 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 Rx N-terminal domain HAP1_N PF04849.13 OWF53756.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AMP-binding PF00501.28 OWF53758.1 - 1.4e-85 287.5 0.0 1.7e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF53758.1 - 1.9e-21 76.8 0.0 3.6e-20 72.7 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OWF53758.1 - 6.5e-17 61.2 0.5 1.5e-16 60.0 0.5 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ABC_membrane_2 PF06472.15 OWF53759.1 - 2.8e-61 207.3 4.8 3.9e-61 206.8 4.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OWF53759.1 - 4.4e-20 72.6 0.0 7.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OWF53759.1 - 0.0057 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OWF53759.1 - 0.045 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 OWF53759.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OWF53759.1 - 0.092 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 OWF53759.1 - 0.13 12.0 0.2 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 OWF53759.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Str_synth PF03088.16 OWF53760.1 - 8.8e-23 80.2 0.0 4.9e-22 77.9 0.0 2.3 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 OWF53760.1 - 5.2e-14 52.4 0.0 1.7e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 OWF53760.1 - 0.00016 22.0 0.3 0.064 13.8 0.1 3.5 3 0 0 3 3 3 1 PQQ-like domain NHL PF01436.21 OWF53760.1 - 0.0012 18.8 0.0 4.7 7.4 0.0 3.9 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.20 OWF53760.1 - 0.019 15.2 0.0 0.072 13.3 0.0 2.1 2 0 0 2 2 2 0 Arylesterase Reg_prop PF07494.11 OWF53760.1 - 0.038 14.2 0.2 2.4 8.7 0.0 3.8 5 0 0 5 5 5 0 Two component regulator propeller CH_2 PF06294.11 OWF53761.1 - 3.8e-29 100.7 0.3 3.8e-29 100.7 0.3 1.8 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OWF53761.1 - 1.8e-14 53.3 0.1 4.6e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 CAMSAP CH domain tRNA-synt_His PF13393.6 OWF53762.1 - 6e-41 140.7 0.0 1.1e-40 139.9 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OWF53762.1 - 7.4e-14 51.7 0.1 1.7e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 OWF53762.1 - 6.5e-08 32.4 0.1 2.6e-07 30.4 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 OWF53762.1 - 0.0016 17.6 0.1 0.004 16.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 OWF53762.1 - 0.0017 18.5 0.3 0.0072 16.5 0.3 2.0 1 0 0 1 1 1 1 WHEP-TRS domain TPR_2 PF07719.17 OWF53763.1 - 1.1e-20 72.0 3.0 0.00037 20.4 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat LON_substr_bdg PF02190.16 OWF53763.1 - 1.5e-19 70.7 0.0 2.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OWF53763.1 - 1.2e-16 60.3 31.2 4.7e-10 39.2 14.4 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 OWF53763.1 - 1.7e-16 59.2 1.6 4.7e-05 23.0 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF53763.1 - 1.4e-14 53.0 0.1 0.005 17.0 0.0 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 OWF53763.1 - 2.1e-12 46.7 25.9 7.8e-08 32.1 9.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF53763.1 - 2.7e-12 46.5 28.4 2.5e-06 27.4 7.7 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF53763.1 - 1e-11 44.5 28.4 1.7e-06 27.8 13.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF53763.1 - 2.7e-11 43.4 28.9 1.3e-06 28.5 7.2 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING TPR_11 PF13414.6 OWF53763.1 - 5.6e-11 41.9 0.1 1.8e-05 24.3 0.1 4.7 3 1 2 5 5 5 2 TPR repeat TPR_16 PF13432.6 OWF53763.1 - 1.1e-10 42.0 1.3 3.7e-05 24.3 0.0 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat zf-RING_2 PF13639.6 OWF53763.1 - 4.1e-10 39.8 30.2 3.6e-07 30.4 13.9 2.7 2 0 0 2 2 2 2 Ring finger domain U-box PF04564.15 OWF53763.1 - 4.4e-10 39.6 0.0 0.0016 18.6 0.0 3.0 2 0 0 2 2 2 2 U-box domain zf-RING_5 PF14634.6 OWF53763.1 - 1.4e-09 37.7 29.4 2.1e-05 24.4 13.1 2.6 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF53763.1 - 1.7e-09 37.4 28.1 1.6e-05 24.6 11.4 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 TPR_17 PF13431.6 OWF53763.1 - 1.4e-08 34.5 0.4 0.28 11.7 0.9 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-RING_10 PF16685.5 OWF53763.1 - 2.1e-08 34.2 21.7 0.00023 21.2 5.1 2.5 2 0 0 2 2 2 2 zinc RING finger of MSL2 TPR_9 PF13371.6 OWF53763.1 - 5.7e-08 32.8 0.3 0.00036 20.6 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF53763.1 - 7.8e-08 32.5 0.7 0.088 13.1 0.4 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF53763.1 - 1.9e-07 31.3 0.8 0.61 11.1 0.0 5.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF53763.1 - 3e-06 26.9 3.3 0.31 11.2 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 OWF53763.1 - 0.00023 21.4 8.2 0.00023 21.4 8.2 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OWF53763.1 - 0.0012 18.7 17.8 0.0038 17.1 5.2 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein TPR_19 PF14559.6 OWF53763.1 - 0.0014 19.1 0.2 2.2 8.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF53763.1 - 0.002 18.0 3.4 4.4 7.3 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF53763.1 - 0.0084 16.3 6.4 0.61 10.3 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_4 PF14570.6 OWF53763.1 - 0.01 15.6 16.5 0.015 15.1 5.4 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TPR_6 PF13174.6 OWF53763.1 - 0.024 15.3 0.8 1.2e+02 3.6 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 OWF53763.1 - 0.16 12.1 0.8 50 4.1 0.0 3.9 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain COMM_domain PF07258.14 OWF53764.1 - 8.4e-16 57.9 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 COMM domain Y_phosphatase PF00102.27 OWF53765.1 - 4.5e-112 373.3 9.6 2.8e-72 243.1 0.1 2.6 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Laminin_EGF PF00053.24 OWF53765.1 - 2.2e-05 24.5 101.5 0.24 11.5 12.3 7.6 1 1 6 7 7 7 3 Laminin EGF domain DSPc PF00782.20 OWF53765.1 - 0.00042 20.1 3.1 0.012 15.4 0.0 3.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain FAM176 PF14851.6 OWF53765.1 - 0.0025 17.5 0.1 0.0065 16.1 0.1 1.6 1 0 0 1 1 1 1 FAM176 family Y_phosphatase3 PF13350.6 OWF53765.1 - 0.0055 16.7 0.9 0.21 11.5 0.1 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OWF53765.1 - 0.039 14.1 0.1 0.039 14.1 0.1 3.4 4 0 0 4 4 4 0 Inositol hexakisphosphate EphA2_TM PF14575.6 OWF53765.1 - 0.066 14.1 0.0 0.19 12.6 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Neurexophilin PF06312.12 OWF53766.1 - 1.2e-06 28.1 1.1 2.4e-06 27.2 1.1 1.4 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF53766.1 - 0.00061 20.6 1.2 0.0029 18.4 0.0 2.4 2 1 1 3 3 3 1 Filamin/ABP280 repeat Invasin_D3 PF09134.10 OWF53766.1 - 0.0016 18.7 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Invasin, domain 3 PC-Esterase PF13839.6 OWF53766.1 - 0.0067 16.2 0.1 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF29 PF01724.16 OWF53766.1 - 0.069 13.4 0.4 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF29 COOH-NH2_lig PF14395.6 OWF53767.1 - 0.0082 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Phage phiEco32-like COOH.NH2 ligase-type 2 Sulfotransfer_2 PF03567.14 OWF53770.1 - 1.3e-29 103.9 2.2 4.6e-26 92.3 0.2 2.4 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OWF53771.1 - 3.7e-30 105.7 2.1 4.1e-26 92.4 0.2 2.4 2 1 0 2 2 2 2 Sulfotransferase family SRCR PF00530.18 OWF53772.1 - 1.8e-09 38.0 0.1 2.4e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF53772.1 - 0.0049 17.4 0.0 0.0088 16.5 0.0 1.5 1 1 0 1 1 1 1 Hepsin, SRCR domain MAM PF00629.23 OWF53773.1 - 7.4e-23 81.2 0.2 1.2e-22 80.5 0.2 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DAG1 PF05454.11 OWF53773.1 - 0.0015 18.0 0.2 0.003 17.0 0.2 1.5 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DAO PF01266.24 OWF53774.1 - 8.1e-42 144.1 0.0 9.1e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF53774.1 - 0.046 13.0 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OWF53774.1 - 0.047 13.2 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Peptidase_C1 PF00112.23 OWF53775.1 - 1.1e-69 234.9 3.0 1.6e-69 234.3 3.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OWF53775.1 - 2e-09 37.8 0.7 2e-09 37.8 0.7 2.4 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OWF53775.1 - 0.051 12.4 1.4 0.42 9.3 0.6 2.1 2 0 0 2 2 2 0 Peptidase C1-like family DIT1_PvcA PF05141.12 OWF53775.1 - 0.078 12.4 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein SPRY PF00622.28 OWF53775.1 - 0.09 12.9 0.1 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 SPRY domain TPR_1 PF00515.28 OWF53776.1 - 7.1e-07 28.8 1.5 0.058 13.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF53776.1 - 0.00067 19.8 2.0 0.0027 17.9 2.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OWF53776.1 - 0.0091 15.7 1.6 0.038 13.7 1.6 2.0 1 1 0 1 1 1 1 TPR repeat TPR_12 PF13424.6 OWF53776.1 - 0.069 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OWF53776.1 - 0.14 12.3 9.6 2.6 8.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PV-1 PF06637.11 OWF53776.1 - 5.3 5.8 12.9 0.12 11.2 5.3 1.8 1 1 1 2 2 2 0 PV-1 protein (PLVAP) RrnaAD PF00398.20 OWF53777.1 - 4.3e-55 186.6 0.0 5.3e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OWF53777.1 - 1.2e-08 35.5 0.0 1.9e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF53777.1 - 7.5e-06 26.5 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF53777.1 - 1.4e-05 25.8 0.0 2.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OWF53777.1 - 0.00042 20.1 0.0 0.00055 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OWF53777.1 - 0.00066 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 OWF53777.1 - 0.0026 17.5 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 OWF53777.1 - 0.0029 17.5 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF53777.1 - 0.0051 16.7 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OWF53777.1 - 0.0075 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 OWF53777.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 OWF53777.1 - 0.021 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 OWF53777.1 - 0.036 13.6 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 OWF53777.1 - 0.041 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 OWF53777.1 - 0.048 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 OWF53777.1 - 0.055 13.3 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 OWF53777.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DREV PF05219.12 OWF53777.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PRMT5 PF05185.16 OWF53777.1 - 0.11 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 OWF53777.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Y_phosphatase PF00102.27 OWF53778.1 - 3.7e-116 386.7 1.4 2.3e-69 233.5 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF53778.1 - 4.2e-05 23.4 1.0 0.0069 16.2 0.0 3.1 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF53778.1 - 0.0019 18.3 1.2 0.024 14.7 0.0 2.8 3 1 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF53778.1 - 0.0035 17.3 0.5 0.079 12.9 0.3 2.8 2 1 0 2 2 2 1 Tyrosine phosphatase family Methyltransf_PK PF05891.12 OWF53778.1 - 0.0095 15.5 0.3 0.65 9.5 0.1 2.4 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase DUF1844 PF08899.11 OWF53778.1 - 0.1 12.9 0.1 5.5 7.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) Laminin_EGF PF00053.24 OWF53779.1 - 0.00012 22.1 113.0 4 7.6 13.8 8.0 1 1 7 8 8 8 5 Laminin EGF domain NUC153 PF08159.12 OWF53780.1 - 1e-09 38.0 0.2 2.7e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 OWF53780.1 - 0.0013 19.0 0.0 0.19 12.0 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF53780.1 - 0.0084 16.9 0.0 8 7.5 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat 5_3_exonuc PF01367.20 OWF53780.1 - 0.82 10.3 3.1 1.3 9.7 0.3 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold F5_F8_type_C PF00754.25 OWF53781.1 - 0.00039 20.5 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain LAX PF15681.5 OWF53782.1 - 0.018 13.8 1.8 0.021 13.6 1.8 1.4 1 1 0 1 1 1 0 Lymphocyte activation family X FGFR3_TM PF18123.1 OWF53782.1 - 0.099 12.2 4.8 0.13 11.8 4.8 1.1 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain MAPEG PF01124.18 OWF53782.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 MAPEG family TMEM154 PF15102.6 OWF53782.1 - 0.12 12.3 0.3 0.15 11.9 0.2 1.3 1 1 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 OWF53782.1 - 0.73 9.8 2.4 1.1 9.3 2.4 1.4 1 1 0 1 1 1 0 Syndecan domain Peptidase_C14 PF00656.22 OWF53783.1 - 7.7e-43 147.2 0.8 9.9e-43 146.9 0.8 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 OWF53784.1 - 1.8e-29 103.4 0.0 2.3e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Mito_fiss_reg PF05308.11 OWF53785.1 - 7e-33 114.7 11.5 2e-32 113.3 11.5 1.7 1 1 0 1 1 1 1 Mitochondrial fission regulator RCDG1 PF15725.5 OWF53785.1 - 0.03 14.8 1.8 0.03 14.8 1.8 3.3 3 1 1 4 4 4 0 Renal cancer differentiation gene 1 protein CAGE1 PF15066.6 OWF53785.1 - 0.042 12.5 1.1 0.063 12.0 1.1 1.2 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family PAC4 PF16093.5 OWF53785.1 - 1.2 9.3 6.3 0.43 10.8 0.6 2.7 2 1 0 2 2 2 0 Proteasome assembly chaperone 4 HMA PF00403.26 OWF53786.1 - 0.00013 22.4 1.5 0.00016 22.0 0.2 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain SH2 PF00017.24 OWF53787.1 - 3.5e-27 94.3 0.1 1.9e-17 63.1 0.0 2.7 3 0 0 3 3 3 2 SH2 domain PI3K_P85_iSH2 PF16454.5 OWF53787.1 - 2.7e-13 49.8 7.7 4e-13 49.3 7.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Med4 PF10018.9 OWF53787.1 - 0.011 15.5 1.6 0.017 14.8 1.6 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 ZapB PF06005.12 OWF53787.1 - 0.031 14.7 5.5 0.23 11.9 5.5 2.3 1 1 0 1 1 1 0 Cell division protein ZapB DASH_Hsk3 PF08227.11 OWF53787.1 - 0.045 14.1 0.2 0.2 12.1 0.0 2.2 2 0 0 2 2 1 0 DASH complex subunit Hsk3 like Hemagglutinin PF00509.18 OWF53787.1 - 0.087 11.2 0.3 0.12 10.8 0.3 1.2 1 0 0 1 1 1 0 Haemagglutinin MFS_3 PF05977.13 OWF53787.1 - 0.092 11.1 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Spc7 PF08317.11 OWF53787.1 - 0.11 11.4 6.7 0.16 10.8 6.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 OWF53787.1 - 0.11 12.5 2.7 0.38 10.8 2.5 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 OWF53787.1 - 0.11 12.3 2.9 0.57 10.0 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator Med9 PF07544.13 OWF53787.1 - 0.18 11.9 2.3 0.27 11.3 0.2 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.6 OWF53787.1 - 0.24 10.7 1.5 0.35 10.2 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 OWF53787.1 - 0.54 10.6 3.7 1.3 9.4 3.7 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FapA PF03961.13 OWF53787.1 - 0.59 8.7 3.3 1.3 7.6 3.1 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 OWF53787.1 - 1.5 9.1 5.3 4.3 7.6 5.3 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein SlyX PF04102.12 OWF53787.1 - 1.8 9.2 4.9 1.1 9.9 0.7 2.7 1 1 2 3 3 3 0 SlyX Sec2p PF06428.11 OWF53787.1 - 2 8.4 5.3 2 8.4 0.2 2.6 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p NAC PF01849.18 OWF53788.1 - 9.4e-25 86.4 0.2 1.8e-24 85.5 0.2 1.5 1 0 0 1 1 1 1 NAC domain SHNi-TPR PF10516.9 OWF53789.1 - 9.3e-14 50.6 1.1 1.8e-13 49.7 0.2 2.1 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 OWF53789.1 - 1e-11 45.0 0.2 2.2e-09 37.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF53789.1 - 1.5e-08 34.2 1.9 0.0004 20.4 0.2 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF53789.1 - 1.3e-07 31.1 0.5 0.00089 19.2 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF53789.1 - 1.9e-07 30.6 0.0 4.7e-05 23.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF53789.1 - 8.5e-06 25.4 2.2 3.4 7.4 0.0 4.9 5 0 0 5 5 5 2 TPR repeat TPR_16 PF13432.6 OWF53789.1 - 0.0045 17.6 0.5 14 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF53789.1 - 0.0051 17.1 0.7 2.1 8.9 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF53789.1 - 0.014 16.0 1.2 3.9 8.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OWF53789.1 - 0.021 14.7 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF53789.1 - 0.072 14.0 2.2 2.1 9.4 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF53789.1 - 0.29 11.4 2.2 5.7 7.2 0.1 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OWF53789.1 - 0.34 11.5 3.4 16 6.1 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_M14 PF00246.24 OWF53790.1 - 1.6e-12 47.8 0.0 4.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OWF53790.1 - 4.7e-07 30.1 0.0 1.5e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Luciferase_3H PF10284.9 OWF53791.1 - 8.3e-13 48.3 2.6 0.39 10.9 0.0 6.3 1 1 5 6 6 6 6 Luciferase helical bundle domain Tautomerase PF01361.21 OWF53791.1 - 0.00043 20.2 1.1 3.1 7.8 0.0 3.8 3 1 1 4 4 4 2 Tautomerase enzyme NADHdh-2_N PF12155.8 OWF53791.1 - 0.016 15.6 0.0 3.2 8.2 0.0 3.1 2 2 2 4 4 4 0 NADH dehydrogenase subunit 2 N-terminal Levi_coat PF01819.17 OWF53791.1 - 0.11 12.5 0.8 0.73 9.9 0.0 2.4 1 1 1 2 2 2 0 Levivirus coat protein DUF2846 PF11008.8 OWF53791.1 - 0.11 12.5 0.0 7.2 6.7 0.0 3.0 1 1 2 4 4 4 0 Protein of unknown function (DUF2846) Luciferase_3H PF10284.9 OWF53792.1 - 8.5e-13 48.3 6.3 0.023 14.8 0.2 6.7 1 1 5 6 6 6 5 Luciferase helical bundle domain LRR_11 PF18831.1 OWF53792.1 - 1e-05 25.0 0.2 52 3.5 0.0 8.9 11 1 0 11 11 11 0 Leucine-rich repeat APP_amyloid PF10515.9 OWF53792.1 - 0.00038 20.9 6.9 1.6 9.3 0.0 5.0 3 2 2 5 5 5 2 Beta-amyloid precursor protein C-terminus Pilosulin PF17499.2 OWF53792.1 - 0.088 13.0 0.5 15 5.9 0.1 3.1 2 1 0 3 3 3 0 Ant venom peptides Invasin_D3 PF09134.10 OWF53792.1 - 2.3 8.6 8.7 9.6 6.6 3.4 2.8 2 1 1 3 3 3 0 Invasin, domain 3 DUF211 PF02680.14 OWF53794.1 - 0.0096 16.1 2.7 26 5.1 0.3 4.3 2 1 3 5 5 5 3 Uncharacterized ArCR, COG1888 Stap_Strp_tox_C PF02876.17 OWF53795.1 - 3.8e-06 27.2 0.2 18 5.7 0.0 4.7 2 2 3 5 5 5 4 Staphylococcal/Streptococcal toxin, beta-grasp domain CobU PF02283.16 OWF53795.1 - 0.62 9.6 5.0 9.2 5.8 0.3 3.5 1 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF2847 PF11009.8 OWF53795.1 - 1.6 8.7 25.9 8.3 6.4 0.3 5.9 1 1 4 6 6 6 0 Protein of unknown function (DUF2847) TMEM144 PF07857.12 OWF53795.1 - 6.1 5.7 7.9 16 4.3 0.6 2.9 2 1 2 4 4 4 0 Transmembrane family, TMEM144 of transporters DUF2482 PF10655.9 OWF53796.1 - 2.1e-10 41.0 139.1 87 3.7 0.5 33.5 1 1 43 47 47 47 36 Hypothetical protein of unknown function (DUF2482) ribosomal_L24 PF17136.4 OWF53797.1 - 0.049 14.0 14.6 41 4.7 1.0 6.6 1 1 3 4 4 4 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 fn3_3 PF14686.6 OWF53797.1 - 0.068 13.0 0.2 0.19 11.5 0.2 1.7 1 1 1 2 2 2 0 Polysaccharide lyase family 4, domain II DUF2685 PF10886.8 OWF53797.1 - 0.36 11.1 12.7 18 5.6 0.3 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF2685) CHZ PF09649.10 OWF53797.1 - 5.4 6.6 36.8 64 3.1 0.1 10.5 12 1 0 12 12 12 0 Histone chaperone domain CHZ DUF3221 PF11518.8 OWF53798.1 - 0.037 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) LIM_bind PF01803.16 OWF53798.1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.0 1 0 0 1 1 1 0 LIM-domain binding protein GTP_EFTU_D2 PF03144.25 OWF53798.1 - 0.18 12.2 0.2 0.32 11.4 0.2 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DZR PF12773.7 OWF53800.1 - 2.6e-102 334.7 377.9 0.00037 20.4 7.1 27.7 1 1 69 70 70 70 70 Double zinc ribbon zinc-ribbon_6 PF10005.9 OWF53800.1 - 1.4e-37 128.2 335.0 3.5 8.4 0.9 47.5 1 1 84 85 85 85 84 zinc-ribbon domain Hyaluronidase_1 PF07212.11 OWF53800.1 - 2.7e-16 59.7 89.1 4.8 6.4 0.1 25.7 1 1 36 39 39 39 15 Hyaluronidase protein (HylP) DUF35_N PF12172.8 OWF53800.1 - 0.0002 21.2 359.9 18 5.3 0.9 51.9 1 1 94 95 95 95 14 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_15 PF17032.5 OWF53800.1 - 0.00056 20.6 437.6 61 4.5 10.8 37.6 1 1 4 5 5 5 0 zinc-ribbon family zf-C3HC4_3 PF13920.6 OWF53800.1 - 0.011 15.6 336.9 16 5.5 0.4 46.4 1 1 81 84 84 84 0 Zinc finger, C3HC4 type (RING finger) BfiI_DBD PF18243.1 OWF53801.1 - 0.0032 17.1 148.6 3.4 7.2 1.0 18.7 1 1 28 29 29 29 28 Metal-independent restriction enzyme BfiI DNA binding domain Tmem26 PF09772.9 OWF53802.1 - 8.3e-97 324.0 8.2 1e-96 323.7 8.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 TMEM154 PF15102.6 OWF53802.1 - 0.089 12.7 0.2 0.52 10.2 0.1 2.3 3 0 0 3 3 3 0 TMEM154 protein family UPF0093 PF03653.13 OWF53802.1 - 0.18 12.1 6.4 0.23 11.7 0.3 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0093) DUF368 PF04018.13 OWF53802.1 - 0.46 10.0 5.3 1.7 8.1 5.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF368) PDZ PF00595.24 OWF53803.1 - 4.1e-43 145.6 6.3 4.1e-10 39.9 0.0 5.8 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 OWF53803.1 - 1.1e-25 89.2 2.2 5e-05 23.1 0.1 5.8 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 OWF53803.1 - 2.3e-13 50.3 9.0 0.024 14.9 0.6 7.1 7 0 0 7 7 7 5 PDZ domain DUF5530 PF17670.1 OWF53803.1 - 0.079 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5530) SOUL PF04832.12 OWF53804.1 - 9.4e-40 136.5 0.2 1.1e-39 136.3 0.2 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Baculo_F PF12259.8 OWF53805.1 - 4.6e-16 58.5 9.1 4.6e-16 58.5 9.1 2.0 2 1 0 2 2 2 1 Baculovirus F protein GARS_A PF01071.19 OWF53805.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ag332 PF04671.12 OWF53806.1 - 3.4 7.7 9.9 34 4.5 0.2 4.4 4 1 1 5 5 5 0 Erythrocyte membrane-associated giant protein antigen 332 GATA PF00320.27 OWF53807.1 - 7.2e-30 102.3 18.6 8.1e-15 54.1 5.5 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 OWF53807.1 - 1.4e-05 24.5 8.6 0.022 14.3 1.8 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 OWF53807.1 - 0.0045 17.1 1.6 1.1 9.5 0.1 2.8 2 1 0 2 2 2 1 Zinc ribbon domain Prim_Zn_Ribbon PF08273.12 OWF53807.1 - 0.013 15.8 9.4 0.39 11.0 2.1 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase ArfGap PF01412.18 OWF53807.1 - 0.018 15.1 6.2 0.22 11.6 0.4 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf DUF2387 PF09526.10 OWF53807.1 - 0.027 14.6 3.0 12 6.1 0.2 3.1 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Auto_anti-p27 PF06677.12 OWF53807.1 - 0.071 13.3 4.9 1.4 9.2 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Elf1 PF05129.13 OWF53807.1 - 0.11 12.6 1.6 14 5.8 0.1 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like TDP43_N PF18694.1 OWF53807.1 - 0.17 11.8 0.2 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 OWF53807.1 - 0.18 11.9 7.9 7.4 6.7 0.7 2.7 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 OWF53807.1 - 0.31 10.9 3.6 9.2 6.2 0.1 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Rubredoxin_2 PF18073.1 OWF53807.1 - 5.4 6.8 12.9 29 4.5 0.1 4.3 4 0 0 4 4 4 0 Rubredoxin metal binding domain C2 PF00168.30 OWF53808.1 - 2.5e-34 117.6 0.0 2.8e-17 62.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain NT-C2 PF10358.9 OWF53808.1 - 5.7e-05 22.9 0.1 0.00057 19.6 0.0 2.5 3 0 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins SecY PF00344.20 OWF53809.1 - 1.8e-76 257.3 9.5 2.1e-76 257.1 9.5 1.0 1 0 0 1 1 1 1 SecY translocase DUF5336 PF17270.2 OWF53809.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.5 3 1 0 3 3 3 0 Family of unknown function (DUF5336) DUF2975 PF11188.8 OWF53809.1 - 7.9 6.4 13.7 0.091 12.6 2.1 3.4 3 1 2 5 5 5 0 Protein of unknown function (DUF2975) Abhydrolase_1 PF00561.20 OWF53810.1 - 2.8e-22 79.6 0.0 4.6e-15 55.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF53810.1 - 8.8e-20 71.0 0.0 1.8e-18 66.7 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OWF53810.1 - 3.3e-18 67.1 0.0 5.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OWF53810.1 - 0.0037 17.0 0.2 0.87 9.2 0.0 3.1 2 2 1 3 3 3 1 Serine hydrolase (FSH1) Esterase PF00756.20 OWF53810.1 - 0.025 14.2 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 OWF53810.1 - 0.033 13.7 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 OWF53810.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 OWF53810.1 - 0.093 12.5 0.0 1.1 9.0 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 OWF53810.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase G-patch PF01585.23 OWF53811.1 - 2.6e-13 49.6 3.4 6.1e-13 48.4 3.4 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 OWF53811.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG PF10961.8 OWF53812.1 - 1.8e-19 70.1 0.3 4.4e-19 68.9 0.3 1.7 1 0 0 1 1 1 1 Selenoprotein SelK_SelG ELK PF03789.13 OWF53812.1 - 0.0012 18.9 0.0 1.2e+02 2.9 0.0 5.7 6 0 0 6 6 6 0 ELK domain DUF4404 PF14357.6 OWF53812.1 - 0.047 14.3 3.7 1.9 9.2 0.4 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) Tox-ODYAM1 PF15642.6 OWF53812.1 - 0.053 12.5 1.0 0.46 9.4 0.3 2.2 1 1 1 2 2 2 0 Toxin in Odyssella and Amoebophilus RR_TM4-6 PF06459.12 OWF53812.1 - 0.1 12.4 1.3 9 6.0 1.8 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NiFe-hyd_HybE PF11939.8 OWF53812.1 - 0.14 12.1 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE UPF0242 PF06785.11 OWF53813.1 - 0.0052 16.9 2.6 0.0052 16.9 2.6 3.2 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 OWF53813.1 - 2.7 8.1 40.8 1 9.4 7.8 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CEL_III_C PF18054.1 OWF53813.1 - 3 7.9 7.5 8.2 6.5 7.5 1.7 1 0 0 1 1 1 0 CEL-III C-terminal PNMA PF14893.6 OWF53814.1 - 5.2e-05 22.8 1.4 7.2e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 PNMA TBK1_CCD1 PF18394.1 OWF53814.1 - 0.0053 16.3 2.0 0.0085 15.7 2.0 1.4 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 zf-CCHC PF00098.23 OWF53814.1 - 0.018 15.1 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OWF53814.1 - 0.026 14.2 1.4 0.055 13.2 1.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4200 PF13863.6 OWF53814.1 - 0.063 13.7 5.7 0.14 12.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 OWF53814.1 - 0.12 10.3 4.4 0.16 9.9 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 OWF53814.1 - 1.1 9.3 5.3 6.5 6.8 5.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) YabA PF06156.13 OWF53814.1 - 1.4 9.6 4.4 7.8 7.2 0.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Vps51 PF08700.11 OWF53814.1 - 1.8 8.7 5.2 0.69 10.0 1.0 2.2 2 0 0 2 2 2 0 Vps51/Vps67 DUF4665 PF15679.5 OWF53814.1 - 1.8 9.2 9.5 1.6 9.4 1.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) ATG16 PF08614.11 OWF53814.1 - 5.4 7.2 11.7 0.14 12.4 3.4 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Presenilin PF01080.17 OWF53814.1 - 5.7 5.6 5.3 8.1 5.1 5.3 1.1 1 0 0 1 1 1 0 Presenilin zf-B_box PF00643.24 OWF53816.1 - 0.0034 17.5 1.8 0.0034 17.5 1.8 1.9 2 0 0 2 2 2 1 B-box zinc finger DUF4600 PF15372.6 OWF53816.1 - 0.037 14.5 1.3 0.084 13.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) zf-UBR PF02207.20 OWF53816.1 - 0.063 13.5 1.4 0.23 11.7 1.4 1.9 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) SGL PF08450.12 OWF53816.1 - 0.064 12.8 0.1 1.7 8.2 0.2 2.5 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Phage_base_V PF04717.12 OWF53817.1 - 5.6e-07 29.5 3.2 18 5.3 0.0 7.7 1 1 7 11 11 11 4 Type VI secretion system, phage-baseplate injector CTD PF12815.7 OWF53817.1 - 2.3 8.8 122.1 3.4 8.3 9.9 11.0 1 1 6 7 7 7 0 Spt5 C-terminal nonapeptide repeat binding Spt4 I-set PF07679.16 OWF53818.1 - 1.3e-83 275.2 0.0 3.5e-18 65.5 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF53818.1 - 1.6e-75 249.7 10.0 5.3e-15 55.8 0.0 6.5 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 OWF53818.1 - 6e-54 180.3 4.7 2.3e-09 37.4 0.1 6.0 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 OWF53818.1 - 3e-45 152.3 1.7 3.4e-09 36.7 0.0 5.9 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 OWF53818.1 - 1.4e-36 124.7 2.4 3.7e-15 56.0 0.0 3.9 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 OWF53818.1 - 8.9e-33 112.7 6.9 4e-10 39.8 0.0 8.3 6 3 1 7 7 7 4 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF53818.1 - 8.7e-16 57.2 0.0 0.011 15.2 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF53818.1 - 4.8e-07 29.7 0.2 4.5 7.4 0.0 5.7 5 1 0 5 5 5 2 C17orf99 Ig domain Pur_ac_phosph_N PF16656.5 OWF53818.1 - 1.3e-06 28.9 7.1 0.015 15.8 0.1 4.7 5 0 0 5 5 4 2 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.5 OWF53818.1 - 1.9e-06 28.1 0.2 0.48 10.7 0.0 5.6 5 1 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 OWF53818.1 - 3e-06 27.2 10.4 0.17 12.0 0.2 5.5 6 0 0 6 6 5 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF53818.1 - 1.7e-05 24.8 0.4 1.8 8.7 0.0 4.8 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 OWF53818.1 - 0.00025 21.2 0.3 4.5 7.5 0.0 4.6 4 0 0 4 4 4 2 Immunoglobulin C2-set domain DUF2369 PF10179.9 OWF53818.1 - 0.096 13.1 0.1 17 5.9 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) GpcrRhopsn4 PF10192.9 OWF53819.1 - 3.3e-60 203.7 19.9 4.3e-60 203.3 19.9 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain CcmH PF03918.14 OWF53819.1 - 1.4 8.2 3.5 1.1 8.6 1.0 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Ammonium_transp PF00909.21 OWF53820.1 - 6.6e-72 242.4 14.0 8.1e-72 242.1 14.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family MAPEG PF01124.18 OWF53821.1 - 4.4e-07 29.9 0.4 4.4e-07 29.9 0.4 1.5 2 0 0 2 2 2 1 MAPEG family MFS_1 PF07690.16 OWF53822.1 - 2.4e-39 135.3 38.5 3e-32 111.9 18.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Galactosyl_T PF01762.21 OWF53823.1 - 2.6e-39 135.1 0.2 3.7e-39 134.6 0.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF53823.1 - 0.023 14.1 0.7 0.09 12.2 0.6 2.0 1 1 0 1 1 1 0 Fringe-like UbiD PF01977.16 OWF53823.1 - 0.029 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Galactosyl_T PF01762.21 OWF53824.1 - 7.4e-44 149.9 0.6 2.3e-43 148.3 0.4 1.8 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 OWF53824.1 - 0.01 15.3 0.2 0.088 12.2 0.1 2.4 1 1 1 2 2 2 0 Fringe-like UbiD PF01977.16 OWF53824.1 - 0.098 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase COX14 PF14880.6 OWF53824.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly G10 PF01125.17 OWF53824.1 - 0.33 10.7 1.8 0.58 9.9 0.3 1.9 2 0 0 2 2 2 0 G10 protein FLgD_tudor PF13861.6 OWF53825.1 - 0.00051 20.2 1.0 11 6.3 0.0 4.1 4 1 1 5 5 5 2 FlgD Tudor-like domain Ser_hydrolase PF06821.13 OWF53825.1 - 0.086 12.7 15.0 0.87 9.4 0.5 3.9 2 2 1 4 4 4 0 Serine hydrolase DIM1 PF02966.16 OWF53825.1 - 0.12 12.2 3.2 15 5.4 0.2 3.3 1 1 1 3 3 3 0 Mitosis protein DIM1 FLgD_tudor PF13861.6 OWF53826.1 - 0.0088 16.3 1.1 8.5 6.7 0.0 3.7 1 1 3 4 4 4 2 FlgD Tudor-like domain LEA_5 PF00477.17 OWF53826.1 - 6.4 7.3 19.0 11 6.5 5.9 3.0 1 1 3 4 4 4 0 Small hydrophilic plant seed protein FLgD_tudor PF13861.6 OWF53827.1 - 0.00032 20.9 0.4 18 5.6 0.0 4.4 3 1 1 5 5 5 2 FlgD Tudor-like domain HTH_ParB PF17762.1 OWF53827.1 - 3.2 7.6 3.6 6.5 6.6 0.0 3.2 3 1 1 4 4 4 0 HTH domain found in ParB protein DIM1 PF02966.16 OWF53827.1 - 4 7.2 6.9 56 3.5 0.1 3.9 1 1 4 5 5 5 0 Mitosis protein DIM1 FLgD_tudor PF13861.6 OWF53828.1 - 0.0023 18.1 16.3 52 4.2 0.2 8.4 3 1 9 12 12 12 5 FlgD Tudor-like domain HTH_ParB PF17762.1 OWF53829.1 - 1.1e-06 28.3 4.3 7.9 6.4 0.0 5.7 2 1 4 6 6 6 4 HTH domain found in ParB protein FLgD_tudor PF13861.6 OWF53829.1 - 0.044 14.0 0.1 24 5.3 0.0 3.2 1 1 4 5 5 5 0 FlgD Tudor-like domain DUF5622 PF18533.1 OWF53829.1 - 0.055 13.6 3.7 13 6.0 0.1 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5622) SF3A3 PF16837.5 OWF53829.1 - 0.058 13.9 2.7 6.2 7.4 2.7 2.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Actin PF00022.19 OWF53830.1 - 1.8e-144 481.4 0.0 6.3e-144 479.5 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 OWF53830.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain DUF2053 PF09767.9 OWF53832.1 - 5.4e-70 234.7 2.3 8.7e-70 234.0 2.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) WD40 PF00400.32 OWF53833.1 - 1.5e-15 57.3 4.9 0.01 16.7 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF5074 PF16819.5 OWF53833.1 - 0.031 14.3 0.1 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) HSL_N PF06350.12 OWF53834.1 - 3.6e-108 361.1 0.7 4.7e-108 360.8 0.7 1.1 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 OWF53834.1 - 2.7e-40 138.5 0.0 2.2e-28 99.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OWF53834.1 - 3.3e-07 29.5 0.0 6.5e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Mab-21 PF03281.14 OWF53835.1 - 1.5e-32 113.1 0.1 2.2e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Mab-21 protein DUF3504 PF12012.8 OWF53837.1 - 0.00053 19.9 0.4 0.00062 19.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Ank_2 PF12796.7 OWF53838.1 - 0.0067 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53838.1 - 0.026 15.1 0.0 0.064 13.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF53838.1 - 0.033 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 OWF53838.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 OWF53839.1 - 0.00071 19.9 0.2 0.081 13.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OWF53839.1 - 0.0017 18.9 0.0 0.012 16.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF53839.1 - 0.0021 18.4 0.0 0.026 15.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OWF53839.1 - 0.0023 18.5 0.0 0.058 14.0 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) FMO-like PF00743.19 OWF53840.1 - 1.6e-71 241.4 0.3 2.1e-51 175.0 0.2 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF53840.1 - 2.8e-16 59.7 0.0 2.7e-14 53.1 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF53840.1 - 6.6e-11 42.0 0.0 7.8e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OWF53840.1 - 3.5e-08 33.4 0.0 0.019 14.6 0.0 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OWF53840.1 - 3.6e-08 33.6 0.0 0.00058 19.9 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 OWF53840.1 - 5.4e-07 29.1 0.1 0.00053 19.2 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OWF53840.1 - 1e-05 25.7 0.0 6.7e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OWF53840.1 - 0.0019 17.5 0.0 0.024 13.9 0.0 2.4 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 OWF53840.1 - 0.022 15.3 0.1 0.54 10.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_7 PF03492.15 OWF53841.1 - 4e-28 98.6 0.0 5.7e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase DUF1573 PF07610.11 OWF53841.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Methyltransf_31 PF13847.6 OWF53842.1 - 1.5e-26 93.0 0.0 1.8e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF53842.1 - 5.6e-20 71.8 0.0 8.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF53842.1 - 1.9e-19 70.1 0.0 2.8e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF53842.1 - 1.5e-18 67.3 0.0 2.9e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF53842.1 - 2e-15 57.0 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF53842.1 - 4.1e-12 45.9 0.0 5.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OWF53842.1 - 1e-08 35.0 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OWF53842.1 - 6.4e-08 32.3 0.0 8.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 OWF53842.1 - 2.5e-07 30.2 0.0 3.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 OWF53842.1 - 4.8e-06 26.2 0.1 6.1e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 OWF53842.1 - 1.6e-05 24.6 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.12 OWF53842.1 - 3.3e-05 23.1 0.0 4.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase GCD14 PF08704.10 OWF53842.1 - 4.7e-05 23.2 0.0 6.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.6 OWF53842.1 - 0.0001 22.3 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OWF53842.1 - 0.00038 20.2 0.0 0.00051 19.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 OWF53842.1 - 0.0018 18.4 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.12 OWF53842.1 - 0.002 17.9 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) CheR PF01739.18 OWF53842.1 - 0.022 14.3 0.0 0.18 11.3 0.0 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 OWF53842.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 OWF53842.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 OWF53842.1 - 0.078 14.0 0.0 0.13 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 OWF53842.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DC_STAMP PF07782.13 OWF53843.1 - 9.9e-36 123.4 1.4 1.6e-35 122.7 1.4 1.3 1 0 0 1 1 1 1 DC-STAMP-like protein GST_N_3 PF13417.6 OWF53844.1 - 4.8e-22 78.2 0.2 8.1e-22 77.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF53844.1 - 2.6e-16 59.7 0.3 6.1e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF53844.1 - 6.7e-13 48.8 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OWF53844.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OWF53844.1 - 0.00017 21.7 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 OWF53844.1 - 0.00041 20.5 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF53844.1 - 0.0025 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4573 PF15140.6 OWF53845.1 - 1.3e-15 57.6 0.0 2e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Plasmodium_HRP PF05403.11 OWF53845.1 - 0.00097 19.0 1.1 0.017 14.9 0.1 2.5 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) Fascin PF06268.13 OWF53845.1 - 0.0071 16.6 9.9 2.5 8.4 0.1 4.1 1 1 3 4 4 4 2 Fascin domain DUF4783 PF16022.5 OWF53845.1 - 0.042 14.0 7.5 4 7.6 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4783) Maf PF02545.14 OWF53845.1 - 0.16 11.8 9.2 14 5.5 0.2 5.2 1 1 5 6 6 6 0 Maf-like protein DUF1831 PF08866.10 OWF53845.1 - 0.19 12.2 21.7 17 5.9 0.2 6.7 1 1 6 8 8 8 0 Putative amino acid metabolism Ribosomal_S11 PF00411.19 OWF53845.1 - 0.32 11.4 2.5 20 5.7 0.1 3.9 1 1 2 4 4 4 0 Ribosomal protein S11 zf-CCCH_4 PF18044.1 OWF53845.1 - 1.2 9.1 13.8 5.6 6.9 0.3 5.9 7 0 0 7 7 7 0 CCCH-type zinc finger DUF4468 PF14730.6 OWF53845.1 - 1.5 9.2 24.2 30 5.0 0.4 7.3 1 1 1 4 4 4 0 Domain of unknown function (DUF4468) with TBP-like fold JHBP PF06585.11 OWF53845.1 - 3.7 6.6 12.4 2.7 7.1 3.1 3.3 1 1 2 3 3 3 0 Haemolymph juvenile hormone binding protein (JHBP) DUF3617 PF12276.8 OWF53845.1 - 8 6.8 11.3 18 5.6 1.7 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3617) Methyltransf_25 PF13649.6 OWF53846.1 - 2.6e-09 37.7 0.0 7.5e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 OWF53846.1 - 3.8e-09 36.4 0.0 7.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OWF53846.1 - 8.2e-09 36.0 0.0 9.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OWF53846.1 - 1.5e-05 24.6 0.1 3.7e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5_C PF17286.2 OWF53846.1 - 4.2e-05 23.5 0.1 6.1e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_23 PF13489.6 OWF53846.1 - 4.6e-05 23.3 0.0 0.00021 21.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF53846.1 - 0.00039 20.2 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF53846.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 OWF53846.1 - 0.003 16.6 0.0 0.0057 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.16 OWF53846.1 - 0.004 17.0 0.0 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.9 OWF53846.1 - 0.0049 16.6 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 OWF53846.1 - 0.024 14.0 0.1 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB CMAS PF02353.20 OWF53846.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 OWF53846.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase CRIM PF16978.5 OWF53846.1 - 0.17 12.0 1.2 1.3 9.2 0.6 2.2 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain p450 PF00067.22 OWF53847.1 - 1.5e-85 287.7 0.1 1.7e-85 287.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 PNTB PF02233.16 OWF53848.1 - 8e-184 611.8 23.7 4.2e-183 609.5 17.2 2.1 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 OWF53848.1 - 2.1e-75 252.7 0.4 5.8e-75 251.3 0.4 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OWF53848.1 - 4.4e-44 150.1 0.1 1.1e-43 148.8 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 OWF53848.1 - 3.3e-31 107.6 3.4 3.3e-31 107.6 3.4 4.5 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 OWF53848.1 - 0.024 14.0 0.5 0.66 9.3 0.1 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 OWF53848.1 - 0.024 13.9 0.2 0.059 12.6 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Iso_dh PF00180.20 OWF53849.1 - 6.4e-78 262.3 0.0 7.4e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IQ PF00612.27 OWF53850.1 - 3.4e-32 107.2 3.7 2.6e-05 23.6 0.1 5.6 5 0 0 5 5 5 5 IQ calmodulin-binding motif DCX PF03607.17 OWF53850.1 - 4.8e-13 49.0 0.0 6.1e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Doublecortin YEATS PF03366.16 OWF53851.1 - 4.3 7.4 15.0 1.2e+02 2.8 0.2 7.0 2 2 7 9 9 9 0 YEATS family YEATS PF03366.16 OWF53852.1 - 0.01 15.8 3.2 4.4 7.4 0.2 3.9 1 1 2 3 3 3 0 YEATS family HATPase_c_2 PF13581.6 OWF53852.1 - 4.4 7.3 7.0 17 5.4 0.7 3.7 1 1 3 4 4 4 0 Histidine kinase-like ATPase domain Euplotes_phero PF05842.11 OWF53852.1 - 5.1 7.7 7.6 15 6.2 1.9 2.5 1 1 1 2 2 2 0 Euplotes octocarinatus mating pheromone protein DCX PF03607.17 OWF53853.1 - 4e-11 42.8 0.0 6.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Doublecortin DUF4090 PF13319.6 OWF53854.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) TPR_14 PF13428.6 OWF53854.1 - 0.19 12.7 0.5 1.2e+02 3.9 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 OWF53855.1 - 2.6e-85 280.2 2.2 1.4e-20 72.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OWF53855.1 - 3.7e-32 110.3 0.5 1.1e-30 105.6 0.5 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 OWF53855.1 - 1.1e-06 28.5 0.2 3.8 7.6 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OWF53855.1 - 2.5e-06 27.5 0.2 3.2 7.9 0.0 5.3 4 3 0 4 4 4 2 RNA recognition motif Limkain-b1 PF11608.8 OWF53855.1 - 6e-06 26.2 1.4 0.65 10.1 0.0 4.5 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 OWF53855.1 - 4.7e-05 23.2 0.0 1 9.3 0.0 4.6 4 1 0 4 4 4 1 Occluded RNA-recognition motif DUF4523 PF15023.6 OWF53855.1 - 0.0037 17.1 0.0 11 5.8 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) OB_RNB PF08206.11 OWF53855.1 - 0.015 15.0 0.2 13 5.5 0.0 3.7 3 0 0 3 3 3 0 Ribonuclease B OB domain SET_assoc PF11767.8 OWF53855.1 - 0.016 14.8 0.0 25 4.6 0.0 4.1 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated DUF4078 PF13300.6 OWF53855.1 - 0.022 15.1 7.5 3 8.2 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4078) Ig_3 PF13927.6 OWF53856.1 - 2.8e-26 91.9 0.4 1.8e-08 34.9 0.1 4.7 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 OWF53856.1 - 3.7e-26 91.0 0.8 1.4e-08 34.7 0.0 4.3 5 0 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 OWF53856.1 - 1.2e-16 60.6 2.1 2.5e-05 24.4 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Bravo_FIGEY PF13882.6 OWF53856.1 - 2.4e-16 60.8 7.9 2.4e-16 60.8 7.9 2.5 3 0 0 3 3 3 1 Bravo-like intracellular region Ig_2 PF13895.6 OWF53856.1 - 2.5e-13 50.1 3.6 3.7e-05 24.0 0.2 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Syndecan PF01034.20 OWF53856.1 - 2.9e-06 27.1 0.2 0.00029 20.7 0.1 2.5 2 0 0 2 2 2 1 Syndecan domain V-set PF07686.17 OWF53856.1 - 0.0043 17.2 7.7 0.69 10.1 0.1 5.5 4 2 0 4 4 4 1 Immunoglobulin V-set domain 7tm_1 PF00001.21 OWF53857.1 - 2e-14 53.6 21.8 3e-14 53.0 21.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF53857.1 - 0.075 12.7 29.4 0.091 12.4 28.7 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Ribosomal_60s PF00428.19 OWF53858.1 - 2e-27 95.6 6.0 2.4e-27 95.3 6.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 OWF53858.1 - 0.0031 18.2 1.9 0.0056 17.4 1.9 1.4 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) Cytomega_UL84 PF06284.11 OWF53858.1 - 0.063 11.7 1.4 0.079 11.4 1.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Thioredoxin PF00085.20 OWF53859.1 - 3.6e-76 251.8 0.3 4.8e-29 100.4 0.2 3.2 3 0 0 3 3 3 3 Thioredoxin OST3_OST6 PF04756.13 OWF53859.1 - 6.3e-10 38.9 0.1 0.0083 15.5 0.0 3.1 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OWF53859.1 - 1.8e-09 38.0 1.9 0.0074 16.7 0.0 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OWF53859.1 - 2.6e-06 27.6 0.7 0.45 10.9 0.0 4.3 3 3 2 5 5 5 2 Thioredoxin-like Thioredoxin_6 PF13848.6 OWF53859.1 - 1.4e-05 25.1 1.0 0.96 9.3 0.1 4.3 3 1 1 4 4 4 2 Thioredoxin-like domain HyaE PF07449.11 OWF53859.1 - 5.6e-05 23.1 0.0 0.43 10.6 0.0 3.3 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 OWF53859.1 - 0.0022 17.8 0.4 0.61 9.9 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 OWF53859.1 - 0.0038 17.4 3.7 3.4 7.9 0.1 3.8 4 1 0 4 4 4 2 Thioredoxin-like TraF PF13728.6 OWF53859.1 - 0.0049 16.7 0.1 0.9 9.3 0.0 2.9 3 0 0 3 3 3 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 OWF53859.1 - 0.0074 16.2 0.7 0.77 9.7 0.1 2.7 2 1 0 2 2 2 1 AhpC/TSA family Mu-like_Com PF10122.9 OWF53859.1 - 0.037 13.5 1.7 11 5.6 0.1 3.3 3 0 0 3 3 3 0 Mu-like prophage protein Com UCH_1 PF13423.6 OWF53859.1 - 0.054 13.1 0.3 11 5.4 0.0 2.8 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Retrotran_gag_2 PF14223.6 OWF53859.1 - 0.056 13.1 0.0 13 5.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type AF0941-like PF14591.6 OWF53859.1 - 0.073 13.6 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 AF0941-like Glutaredoxin PF00462.24 OWF53859.1 - 4.6 7.5 7.7 46 4.3 0.6 4.1 3 1 1 4 4 4 0 Glutaredoxin ANAPC4_WD40 PF12894.7 OWF53860.1 - 5.5e-13 49.0 4.7 3.6e-05 24.0 0.0 5.7 5 1 1 7 7 6 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OWF53860.1 - 6.6e-06 26.0 8.4 8.6e-06 25.7 2.1 3.2 1 1 2 3 3 3 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 OWF53860.1 - 1.5e-05 24.2 6.9 0.00066 18.8 0.1 3.5 3 1 1 4 4 4 2 Coatomer WD associated region eIF2A PF08662.11 OWF53860.1 - 2.3e-05 24.3 2.5 3.8e-05 23.7 1.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OWF53860.1 - 3.9e-05 24.3 1.2 2.9 8.9 0.0 5.3 5 1 0 5 5 4 1 WD domain, G-beta repeat TPR_7 PF13176.6 OWF53860.1 - 0.00073 19.4 6.6 0.058 13.4 0.6 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OWF53860.1 - 0.11 12.3 8.0 2.6 8.0 0.4 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 OWF53860.1 - 0.5 10.7 3.5 0.7 10.2 1.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DZR PF12773.7 OWF53860.1 - 1.2 9.3 11.8 1.8 8.6 1.4 2.6 1 1 1 2 2 2 0 Double zinc ribbon TPR_16 PF13432.6 OWF53860.1 - 1.2 9.8 12.8 1.7 9.3 0.1 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat Zn_Tnp_IS1595 PF12760.7 OWF53860.1 - 1.3 9.0 9.6 0.35 10.9 2.5 3.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PPR PF01535.20 OWF53860.1 - 1.7 9.1 3.5 35 5.0 0.0 4.1 3 1 1 4 4 4 0 PPR repeat Ribosomal_L7Ae PF01248.26 OWF53861.1 - 6.6e-26 89.9 0.0 7.6e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 OWF53861.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MAM PF00629.23 OWF53862.1 - 1.3e-55 187.7 0.0 9e-28 97.2 0.1 3.5 3 0 0 3 3 3 3 MAM domain, meprin/A5/mu Trypsin PF00089.26 OWF53862.1 - 2.4e-54 184.5 1.8 2.6e-54 184.4 0.5 1.8 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.18 OWF53862.1 - 2.8e-54 181.0 156.4 3.4e-10 40.0 9.0 10.8 11 0 0 11 11 11 9 Low-density lipoprotein receptor domain class A Fz PF01392.22 OWF53862.1 - 1.2e-37 128.9 35.0 7.8e-18 65.1 6.1 5.9 7 1 0 7 7 7 3 Fz domain SEA PF01390.20 OWF53862.1 - 9.7e-13 48.1 0.2 3.4e-12 46.4 0.2 2.0 1 0 0 1 1 1 1 SEA domain SRCR_2 PF15494.6 OWF53862.1 - 2.5e-08 34.3 0.8 1.9e-07 31.5 0.8 2.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 OWF53862.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) BsuPI PF12690.7 OWF53862.1 - 0.023 14.7 0.6 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 Intracellular proteinase inhibitor Trypsin_2 PF13365.6 OWF53862.1 - 0.043 14.7 0.5 0.28 12.1 0.0 2.6 3 0 0 3 3 3 0 Trypsin-like peptidase domain GST_N_4 PF17172.4 OWF53863.1 - 1.4e-30 105.9 0.0 2.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF53863.1 - 6.9e-23 80.2 0.1 1.7e-22 79.0 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF53863.1 - 6.1e-14 51.8 0.0 1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF53863.1 - 3.6e-08 33.8 0.0 3e-07 30.8 0.0 2.3 2 1 1 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 OWF53863.1 - 1.2e-06 28.6 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF53863.1 - 3.9e-06 27.0 0.0 9.6e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EphA2_TM PF14575.6 OWF53863.1 - 0.18 12.7 0.1 1 10.3 0.1 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pyridoxal_deC PF00282.19 OWF53864.1 - 1.5e-19 69.9 0.0 9.8e-10 37.7 0.0 3.3 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Crystall PF00030.19 OWF53864.1 - 2.5e-17 62.8 0.0 4.8e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Beta/Gamma crystallin 7tm_1 PF00001.21 OWF53865.1 - 6e-26 91.3 16.7 7.8e-26 91.0 16.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF53865.1 - 7.3e-20 71.5 17.8 7.3e-20 71.5 17.8 1.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF898 PF05987.13 OWF53865.1 - 0.0021 17.2 2.9 0.0021 17.2 2.9 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) Phage_tail_U PF06141.11 OWF53866.1 - 6.1e-07 29.9 0.2 42 4.5 0.0 7.5 1 1 4 8 8 8 0 Phage minor tail protein U TPP1 PF10341.9 OWF53866.1 - 0.012 15.5 3.7 37 4.3 0.1 5.4 5 1 1 6 6 6 0 Shelterin complex subunit, TPP1/ACD PilO PF04350.13 OWF53866.1 - 0.016 15.3 2.7 15 5.7 0.0 4.6 2 1 3 5 5 5 0 Pilus assembly protein, PilO DNase-RNase PF02577.14 OWF53866.1 - 0.044 13.4 1.0 25 4.5 0.0 4.2 3 2 2 5 5 5 0 Bifunctional nuclease REV PF00424.18 OWF53866.1 - 0.17 11.9 2.4 1.1e+02 2.9 0.0 4.7 4 1 2 6 6 6 0 REV protein (anti-repression trans-activator protein) ISP3_C PF18045.1 OWF53866.1 - 0.19 11.6 0.0 18 5.3 0.0 3.6 3 1 0 3 3 3 0 ISP3 C-terminal LIME1 PF15332.6 OWF53866.1 - 0.27 10.8 1.4 20 4.7 0.0 3.0 2 1 1 3 3 3 0 Lck-interacting transmembrane adapter 1 LysR_substrate PF03466.20 OWF53866.1 - 0.64 9.3 2.9 25 4.2 0.1 3.4 4 0 0 4 4 4 0 LysR substrate binding domain Pes-10 PF07149.11 OWF53866.1 - 0.7 8.9 6.3 2.3 7.2 0.0 4.1 4 1 0 5 5 5 0 Pes-10 Ac76 PF05814.11 OWF53867.1 - 0.02 14.9 1.8 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Flavi_NS4A PF01350.17 OWF53867.1 - 0.11 12.5 1.9 0.11 12.5 0.1 1.8 2 1 0 2 2 2 0 Flavivirus non-structural protein NS4A PC4 PF02229.16 OWF53868.1 - 3.9e-18 64.8 0.0 2.5e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) RNA_pol PF00940.19 OWF53869.1 - 1.3e-149 498.6 1.7 2.3e-149 497.7 1.7 1.5 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OWF53869.1 - 3.1e-24 86.0 0.2 3.1e-24 86.0 0.2 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_3 PF13812.6 OWF53869.1 - 0.00012 22.0 0.0 0.00059 19.9 0.0 2.2 1 0 0 1 1 1 1 Pentatricopeptide repeat domain FANCM-MHF_bd PF16783.5 OWF53869.1 - 0.078 13.1 1.5 0.17 12.0 0.1 2.4 2 0 0 2 2 2 0 FANCM to MHF binding domain PPR_2 PF13041.6 OWF53869.1 - 0.1 12.8 0.0 0.36 11.1 0.0 2.1 1 0 0 1 1 1 0 PPR repeat family EHN PF06441.12 OWF53869.1 - 0.14 12.5 1.9 26 5.2 0.4 4.0 3 1 0 3 3 3 0 Epoxide hydrolase N terminus TIR PF01582.20 OWF53870.1 - 2.8e-17 63.1 0.1 6.2e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF53870.1 - 3.8e-15 56.5 0.0 8.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF53870.1 - 0.024 15.1 4.1 0.47 11.0 0.0 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF1863 PF08937.11 OWF53870.1 - 0.12 12.7 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) LRR_1 PF00560.33 OWF53870.1 - 8.8 7.3 9.2 72 4.5 0.2 5.3 5 2 0 5 5 5 0 Leucine Rich Repeat TIM PF00121.18 OWF53871.1 - 3.2e-89 298.5 0.0 3.7e-89 298.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 OWF53871.1 - 0.08 12.4 0.0 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 CutC family Smg8_Smg9 PF10220.9 OWF53872.1 - 1.1e-257 857.9 5.8 1.4e-255 850.9 5.8 2.0 1 1 0 1 1 1 1 Smg8_Smg9 Homeobox_KN PF05920.11 OWF53873.1 - 1.8e-15 56.6 0.1 3.1e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OWF53873.1 - 2.8e-06 27.1 0.2 5.2e-06 26.2 0.2 1.5 1 1 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF53873.1 - 0.014 14.9 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez RecQ_Zn_bind PF16124.5 OWF53875.1 - 2.1e-06 28.4 0.3 4.3e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 OWF53875.1 - 0.00015 22.1 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_71 PF03659.14 OWF53877.1 - 0.072 11.9 0.1 0.094 11.5 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Pneumo_matrix PF03393.16 OWF53880.1 - 0.0032 16.7 12.7 0.77 8.9 1.3 3.6 1 1 3 4 4 4 4 Pneumovirus matrix protein PAXX PF15384.6 OWF53880.1 - 0.023 14.4 0.7 3.5 7.3 0.1 3.3 2 1 2 4 4 4 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 FSH1 PF03959.13 OWF53880.1 - 0.18 11.4 2.5 11 5.6 0.1 4.0 2 2 1 4 4 4 0 Serine hydrolase (FSH1) DUF3868 PF12984.7 OWF53880.1 - 1.9 8.4 8.0 1.5 8.6 0.9 3.3 1 1 1 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3868) RUN PF02759.19 OWF53881.1 - 1.4e-09 38.0 0.1 2.8e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 RUN domain DUF3837 PF12939.7 OWF53881.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3837) Sec1 PF00995.23 OWF53882.1 - 1e-125 421.2 0.1 1.2e-125 421.0 0.1 1.0 1 0 0 1 1 1 1 Sec1 family NCBP3 PF10309.9 OWF53883.1 - 1.3e-17 63.4 0.0 2.6e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 SR-25 PF10500.9 OWF53883.1 - 5.6e-06 26.1 40.3 5.6e-06 26.1 40.3 5.6 5 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein mit_SMPDase PF14724.6 OWF53884.1 - 2.7e-142 475.4 1.3 6.6e-142 474.1 1.3 1.5 1 1 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase Mpv17_PMP22 PF04117.12 OWF53885.1 - 6.1e-22 77.6 1.5 1.2e-21 76.7 1.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2946 PF11162.8 OWF53886.1 - 0.21 12.3 5.9 0.11 13.2 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Glyoxalase_6 PF18029.1 OWF53887.1 - 3e-05 24.7 0.0 0.0016 19.2 0.0 3.0 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.25 OWF53887.1 - 0.014 15.6 0.0 0.084 13.1 0.0 2.3 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SpoU_methylase PF00588.19 OWF53888.1 - 2.4e-16 60.2 0.0 2.1e-13 50.7 0.0 3.1 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OWF53888.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding EMP24_GP25L PF01105.24 OWF53889.1 - 1.6e-48 165.1 0.2 1.8e-48 164.9 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 OWF53889.1 - 0.0014 18.8 0.1 0.0024 18.1 0.1 1.4 1 1 0 1 1 1 1 SdrD B-like domain Jnk-SapK_ap_N PF09744.9 OWF53890.1 - 1e-34 120.0 22.3 1e-34 120.0 22.3 3.0 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.8 OWF53890.1 - 5.4e-13 49.0 0.2 5.4e-13 49.0 0.2 3.1 3 2 0 3 3 3 1 Rab interacting lysosomal protein ADIP PF11559.8 OWF53890.1 - 0.006 16.7 17.5 0.006 16.7 17.5 3.2 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding Arch_fla_DE PF04659.13 OWF53890.1 - 0.062 13.2 1.7 0.25 11.2 1.7 2.1 1 0 0 1 1 1 0 Archaeal flagella protein DUF3584 PF12128.8 OWF53890.1 - 0.61 7.5 39.2 0.9 7.0 39.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_34 PF13872.6 OWF53892.1 - 1.3e-140 467.6 0.0 2e-140 466.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 OWF53892.1 - 2.2e-117 391.6 0.2 4.9e-117 390.4 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 OWF53892.1 - 3.8e-07 30.3 0.4 2.6e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OWF53892.1 - 0.0055 17.0 0.0 0.022 15.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SR-25 PF10500.9 OWF53892.1 - 0.054 13.1 23.5 0.13 11.8 23.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SET PF00856.28 OWF53893.1 - 6.4e-17 62.5 2.8 1.4e-16 61.3 0.2 2.6 2 1 0 2 2 2 1 SET domain Secretin_N_2 PF07655.13 OWF53893.1 - 0.015 15.8 6.6 0.015 15.8 6.6 2.1 1 1 1 2 2 2 0 Secretin N-terminal domain MAM33 PF02330.16 OWF53894.1 - 1e-21 77.9 0.2 1.5e-21 77.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein Lipocalin_4 PF13648.6 OWF53894.1 - 0.06 14.3 0.2 0.12 13.3 0.2 1.5 1 1 0 1 1 1 0 Lipocalin-like domain Amidase PF01425.21 OWF53895.1 - 1.1e-99 334.5 0.0 1.3e-99 334.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 OWF53896.1 - 6e-99 332.0 0.0 7.5e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Amidase NHL PF01436.21 OWF53897.1 - 6.3e-07 29.1 0.1 0.036 14.1 0.0 3.9 4 0 0 4 4 4 2 NHL repeat DUF3659 PF12396.8 OWF53897.1 - 0.0086 16.0 0.0 4.7 7.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF719 PF05334.13 OWF53898.1 - 1.3e-53 182.1 15.8 2.2e-41 142.2 4.3 5.4 3 2 1 5 5 5 2 Protein of unknown function (DUF719) zf-C2H2_jaz PF12171.8 OWF53899.1 - 4.9e-07 29.9 1.5 8.6e-07 29.1 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF53899.1 - 1.7e-06 28.2 1.4 2.7e-06 27.6 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 OWF53899.1 - 0.00026 20.7 1.1 0.00048 19.9 1.1 1.4 1 0 0 1 1 1 1 U1 zinc finger SNRNP27 PF08648.12 OWF53899.1 - 0.0042 17.1 0.0 0.0042 17.1 0.0 2.6 3 1 0 3 3 3 1 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2 PF00096.26 OWF53899.1 - 0.14 12.7 1.0 0.28 11.7 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Cgr1 PF03879.14 OWF53899.1 - 0.28 11.6 28.6 0.14 12.5 18.2 2.2 2 0 0 2 2 2 0 Cgr1 family Vma12 PF11712.8 OWF53899.1 - 0.93 9.6 7.0 7.9 6.5 3.5 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TFIIF_beta_N PF17683.1 OWF53899.1 - 0.99 10.1 8.2 1.3 9.7 5.1 2.0 2 0 0 2 2 2 0 TFIIF, beta subunit N-terminus DUF2589 PF11655.8 OWF53899.1 - 4 7.8 8.3 7.9 6.8 8.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2589) Vfa1 PF08432.10 OWF53899.1 - 8.3 6.7 23.1 0.25 11.7 15.4 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HMG_box PF00505.19 OWF53900.1 - 0.00078 19.8 0.4 0.0021 18.5 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box KIAA1430 PF13879.6 OWF53901.1 - 7.7e-09 36.2 8.7 7.7e-09 36.2 8.7 3.9 3 1 1 4 4 4 1 KIAA1430 homologue ING PF12998.7 OWF53902.1 - 8.3e-24 84.1 3.1 8.3e-24 84.1 3.1 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding TraG-D_C PF12696.7 OWF53902.1 - 0.0049 16.8 0.8 0.23 11.5 0.0 2.3 2 0 0 2 2 2 1 TraM recognition site of TraD and TraG Interferon PF00143.19 OWF53902.1 - 0.053 13.7 0.8 0.095 12.9 0.8 1.5 1 0 0 1 1 1 0 Interferon alpha/beta domain RP-C_C PF11800.8 OWF53902.1 - 1.6 8.8 6.4 5.2 7.1 4.2 2.0 1 1 0 2 2 2 0 Replication protein C C-terminal region AMP-binding PF00501.28 OWF53903.1 - 5.7e-79 265.7 0.0 8.8e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme adh_short PF00106.25 OWF53903.1 - 2.9e-57 193.3 1.3 6.5e-57 192.1 1.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 OWF53903.1 - 4.5e-54 183.3 0.0 1.7e-53 181.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 OWF53903.1 - 2.8e-41 141.6 0.5 2.8e-41 141.6 0.5 1.9 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OWF53903.1 - 1.1e-19 70.9 0.3 3.9e-12 46.2 0.0 3.7 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OWF53903.1 - 5.5e-17 62.2 0.6 4.9e-14 52.7 0.4 2.5 2 0 0 2 2 2 2 KR domain PP-binding PF00550.25 OWF53903.1 - 2.3e-15 56.7 0.0 5.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OWF53903.1 - 3.3e-13 49.3 4.8 5.8e-10 38.6 0.0 3.5 4 1 0 4 4 4 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OWF53903.1 - 2e-08 33.7 1.0 0.00016 20.9 0.0 3.2 3 0 0 3 3 3 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OWF53903.1 - 1.6e-07 31.1 0.1 0.00027 20.4 0.0 3.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OWF53903.1 - 2.7e-06 26.8 3.5 0.0078 15.4 0.2 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 OWF53903.1 - 4.7e-06 27.5 0.2 1.4e-05 26.0 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain THF_DHG_CYH_C PF02882.19 OWF53903.1 - 0.036 13.4 0.1 0.094 12.0 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 OWF53903.1 - 0.094 12.3 2.7 3.4 7.2 1.1 3.0 3 0 0 3 3 3 0 NmrA-like family Pkinase PF00069.25 OWF53904.1 - 2.1e-70 237.1 0.1 3.1e-70 236.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF53904.1 - 8.3e-44 149.8 0.0 1.5e-43 149.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB1 PF18190.1 OWF53904.1 - 3.3e-41 139.8 0.1 1.7e-40 137.6 0.1 2.3 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 OWF53904.1 - 1.9e-36 125.0 3.5 1.7e-34 118.8 0.2 3.5 3 0 0 3 3 3 1 Polo-like Kinase 4 Polo Box 2 POLO_box PF00659.18 OWF53904.1 - 4.9e-07 29.8 0.0 2.7e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 POLO box duplicated region Pkinase_fungal PF17667.1 OWF53904.1 - 1.8e-05 23.7 0.1 4.2e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OWF53904.1 - 0.0015 18.0 0.0 0.0099 15.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OWF53904.1 - 0.014 14.4 0.3 0.014 14.4 0.3 2.3 2 1 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 OWF53904.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Helo_like_N PF17111.5 OWF53904.1 - 0.73 9.2 3.2 7.7 5.8 0.4 3.1 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins DUF2281 PF10047.9 OWF53904.1 - 0.76 10.5 2.7 1 10.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) HSP70 PF00012.20 OWF53905.1 - 6.2e-177 589.4 23.1 1.6e-171 571.5 6.4 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OWF53905.1 - 8.5e-11 41.2 0.0 1.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein DUF2205 PF10224.9 OWF53906.1 - 3e-28 97.6 2.1 4.2e-28 97.1 2.1 1.2 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 OWF53906.1 - 0.00012 22.2 5.7 0.075 13.3 2.2 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper FlaC_arch PF05377.11 OWF53906.1 - 0.00085 19.7 1.9 0.0014 19.0 1.9 1.4 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 OWF53906.1 - 0.0014 18.5 4.7 0.0018 18.1 4.7 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 OWF53906.1 - 0.0042 17.7 4.3 0.0056 17.3 4.3 1.2 1 0 0 1 1 1 1 Initiation control protein YabA ZapB PF06005.12 OWF53906.1 - 0.0047 17.3 2.7 0.0072 16.7 2.7 1.3 1 0 0 1 1 1 1 Cell division protein ZapB CENP-H PF05837.12 OWF53906.1 - 0.014 15.8 5.6 0.018 15.5 5.6 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DASH_Dad4 PF08650.10 OWF53906.1 - 0.023 14.7 1.0 0.034 14.1 1.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 V_ATPase_I PF01496.19 OWF53906.1 - 0.034 12.1 1.7 0.035 12.0 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 OWF53906.1 - 0.036 14.2 1.9 0.036 14.2 1.9 1.8 1 1 1 2 2 2 0 bZIP transcription factor Sas10_Utp3 PF04000.15 OWF53906.1 - 0.037 14.7 1.3 0.074 13.7 1.3 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family DASH_Hsk3 PF08227.11 OWF53906.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like WW PF00397.26 OWF53907.1 - 1.4e-17 63.4 1.9 8.7e-09 35.3 0.1 2.5 2 0 0 2 2 2 2 WW domain FERM_M PF00373.18 OWF53907.1 - 1.6e-15 57.6 0.6 3.6e-15 56.4 0.6 1.6 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.24 OWF53907.1 - 7.2e-09 35.9 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain FERM_N PF09379.10 OWF53907.1 - 0.00011 22.1 0.1 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain PDZ_6 PF17820.1 OWF53907.1 - 0.00018 21.3 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF53907.1 - 0.00047 20.4 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain FERM_f0 PF16511.5 OWF53907.1 - 0.016 15.5 0.1 0.055 13.8 0.1 1.9 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM YqgC PF17430.2 OWF53907.1 - 0.023 14.8 0.3 0.07 13.2 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized YqgC-like CwfJ_C_1 PF04677.15 OWF53907.1 - 0.068 13.0 0.3 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 zf-B_box PF00643.24 OWF53908.1 - 2.6e-08 33.9 3.3 7.2e-08 32.5 3.3 1.8 1 0 0 1 1 1 1 B-box zinc finger Vps16_N PF04841.13 OWF53908.1 - 0.0094 14.7 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region NHL PF01436.21 OWF53908.1 - 0.065 13.3 2.7 81 3.5 0.0 4.6 5 0 0 5 5 5 0 NHL repeat FAM181 PF15238.6 OWF53909.1 - 2.1e-33 116.4 8.0 1.4e-31 110.4 6.1 2.4 1 1 0 1 1 1 1 FAM181 Thioesterase PF00975.20 OWF53910.1 - 4.2e-47 161.2 0.0 4.7e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 OWF53910.1 - 0.0024 18.5 0.0 0.0032 18.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 OWF53910.1 - 0.0099 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 OWF53910.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OWF53910.1 - 0.096 12.2 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Sel1 PF08238.12 OWF53911.1 - 1.3e-25 89.2 17.3 4.6e-07 30.3 0.0 6.2 6 0 0 6 6 6 4 Sel1 repeat TPR_16 PF13432.6 OWF53911.1 - 0.0014 19.2 10.9 0.0065 17.1 0.1 3.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF53911.1 - 0.024 15.2 11.4 0.059 14.0 0.0 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OWF53911.1 - 1.3 9.0 0.0 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_delta2 PF13177.6 OWF53912.1 - 4.2e-13 49.4 0.3 1.3e-12 47.8 0.2 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OWF53912.1 - 4.3e-07 30.0 0.2 9e-07 29.0 0.2 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 OWF53912.1 - 1e-06 29.2 0.0 2.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OWF53912.1 - 0.00011 22.6 0.1 0.00035 20.9 0.1 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 OWF53912.1 - 0.00028 20.7 0.1 0.0008 19.2 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OWF53912.1 - 0.00077 19.9 0.1 0.0033 17.8 0.0 2.1 2 2 0 2 2 2 1 AAA ATPase domain ATPgrasp_ST PF14397.6 OWF53912.1 - 0.0021 17.3 0.2 0.0038 16.5 0.2 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp AAA_22 PF13401.6 OWF53912.1 - 0.0049 17.2 0.2 0.018 15.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OWF53912.1 - 0.0053 16.8 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OWF53912.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Entericidin PF08085.11 OWF53913.1 - 0.0055 16.7 0.0 1.9e+02 2.2 0.0 6.4 8 0 0 8 8 8 0 Entericidin EcnA/B family DUF1451 PF07295.11 OWF53913.1 - 0.55 10.3 9.9 3.9 7.5 9.8 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain Ion_trans PF00520.31 OWF53915.1 - 2.2e-31 109.0 6.8 3.4e-31 108.4 6.8 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 OWF53915.1 - 6.7e-27 93.5 1.2 6.7e-27 93.5 1.2 1.8 2 0 0 2 2 2 1 Transient receptor ion channel II Ank_2 PF12796.7 OWF53915.1 - 1.2e-10 41.8 0.3 2.7e-06 27.9 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF53915.1 - 5.2e-10 39.7 0.1 0.00096 19.7 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 OWF53915.1 - 3.9e-09 35.7 8.7 2.9e-08 32.8 8.7 1.9 1 1 0 1 1 1 1 Polycystin cation channel Ank_3 PF13606.6 OWF53915.1 - 9.7e-08 31.7 2.2 0.0074 16.7 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeat Ank PF00023.30 OWF53915.1 - 8.2e-06 26.0 0.3 0.33 11.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OWF53915.1 - 0.00011 22.4 0.3 0.59 10.5 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TMEM52 PF14979.6 OWF53916.1 - 2.9 7.8 11.8 0.092 12.7 5.2 1.8 2 0 0 2 2 2 0 Transmembrane 52 GatB_N PF02934.15 OWF53917.1 - 3.7e-98 328.3 0.0 4.9e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OWF53917.1 - 1.8e-09 37.6 0.9 3.5e-09 36.7 0.1 1.8 2 0 0 2 2 2 1 GatB domain ANF_receptor PF01094.28 OWF53918.1 - 7.6e-56 189.7 0.0 1.1e-55 189.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF53918.1 - 4.2e-21 76.0 0.0 7.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 OWF53919.1 - 6.9e-45 153.6 7.2 1e-44 153.1 7.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR MIEAP PF16026.5 OWF53920.1 - 2.6e-41 142.1 2.5 2.6e-41 142.1 2.5 4.4 4 2 1 5 5 5 1 Mitochondria-eating protein GAS PF13851.6 OWF53920.1 - 0.0052 16.2 14.2 0.0052 16.2 14.2 7.5 5 2 3 8 8 8 1 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 OWF53920.1 - 0.022 14.1 50.1 0.076 12.4 2.9 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4407) HSBP1 PF06825.12 OWF53920.1 - 0.03 14.2 2.2 0.4 10.6 0.2 3.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FUSC PF04632.12 OWF53920.1 - 6.5 5.2 12.3 3.4 6.1 0.8 3.0 2 1 0 2 2 2 0 Fusaric acid resistance protein family Reprolysin_5 PF13688.6 OWF53920.1 - 7.1 6.7 6.4 2 8.5 0.6 2.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 7tm_1 PF00001.21 OWF53921.1 - 2e-13 50.3 24.7 1.1e-12 47.9 24.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) VWD PF00094.25 OWF53922.1 - 0.002 18.4 0.1 0.0086 16.4 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type D domain TMEM154 PF15102.6 OWF53923.1 - 8.7e-05 22.5 0.2 0.00021 21.2 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family Mucin PF01456.17 OWF53923.1 - 0.0025 17.8 10.7 0.0025 17.8 10.7 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein SID-1_RNA_chan PF13965.6 OWF53923.1 - 0.036 12.5 0.5 0.059 11.8 0.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RIFIN PF02009.16 OWF53923.1 - 0.1 12.5 3.7 0.27 11.1 0.1 2.1 1 1 0 2 2 2 0 Rifin Orf78 PF06024.12 OWF53923.1 - 0.16 12.3 0.0 0.71 10.2 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) RIFIN PF02009.16 OWF53924.1 - 3.8e-05 23.7 2.1 5.1e-05 23.3 2.1 1.1 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 OWF53924.1 - 0.0034 17.3 7.1 0.0075 16.2 7.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 OWF53924.1 - 0.0083 16.4 2.0 0.015 15.5 2.0 1.3 1 0 0 1 1 1 1 Glycophorin A CD34_antigen PF06365.12 OWF53924.1 - 0.048 13.2 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4245 PF14030.6 OWF53924.1 - 0.085 12.9 0.1 0.085 12.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4245) FSA_C PF10479.9 OWF53924.1 - 1.2 7.2 12.0 1.5 6.8 12.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AJAP1_PANP_C PF15298.6 OWF53924.1 - 2.8 8.1 25.1 0.35 11.1 20.3 1.8 1 1 1 2 2 2 0 AJAP1/PANP C-terminus CUB PF00431.20 OWF53925.1 - 2.3e-14 53.7 0.2 3.5e-14 53.1 0.2 1.2 1 0 0 1 1 1 1 CUB domain DUF3922 PF13059.6 OWF53925.1 - 0.011 16.1 0.7 0.02 15.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) DUF3149 PF11346.8 OWF53925.1 - 0.61 9.8 4.7 1.2 8.8 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) LRR_6 PF13516.6 OWF53927.1 - 1.4e-22 77.7 19.9 0.011 15.7 0.1 8.6 9 0 0 9 9 9 6 Leucine Rich repeat EF-hand_7 PF13499.6 OWF53927.1 - 7.1e-09 36.0 0.3 2.5e-08 34.2 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain pair LRR_1 PF00560.33 OWF53927.1 - 2e-06 27.6 4.5 11 7.1 0.2 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat EF-hand_1 PF00036.32 OWF53927.1 - 0.00046 19.6 10.3 0.003 17.0 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OWF53927.1 - 0.00073 19.3 7.7 0.033 14.1 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain LRR_8 PF13855.6 OWF53927.1 - 0.00083 19.1 15.6 0.0019 18.0 0.3 4.8 4 2 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OWF53927.1 - 0.0037 17.7 14.3 0.069 13.6 0.0 4.1 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) EF-hand_5 PF13202.6 OWF53927.1 - 0.008 15.6 2.8 0.23 11.0 0.3 2.9 2 0 0 2 2 2 1 EF hand ASXH PF13919.6 OWF53927.1 - 0.033 14.2 0.2 0.08 13.0 0.2 1.6 1 0 0 1 1 1 0 Asx homology domain 7tm_1 PF00001.21 OWF53930.1 - 3.2e-50 170.9 5.5 4e-50 170.6 5.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 OWF53930.1 - 0.0019 17.6 7.5 0.0059 16.0 7.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 OWF53930.1 - 0.0025 17.6 0.1 0.0025 17.6 0.1 3.1 2 1 1 3 3 3 2 Olfactory receptor DUF5021 PF16424.5 OWF53931.1 - 7.2e-06 25.9 3.5 14 5.5 0.3 5.8 1 1 4 5 5 5 2 Domain of unknown function (DUF5021) DUF3908 PF13048.6 OWF53931.1 - 0.0014 18.9 48.0 1.3 9.3 2.7 5.2 1 1 4 5 5 5 5 Protein of unknown function (DUF3908) CedA PF10729.9 OWF53931.1 - 0.0086 15.9 36.3 4.2 7.3 1.9 7.9 1 1 6 7 7 7 5 Cell division activator CedA MTA_R1 PF17226.2 OWF53931.1 - 0.037 14.2 7.0 42 4.4 0.0 6.2 1 1 6 7 7 7 0 MTA R1 domain Cu-oxidase_3 PF07732.15 OWF53933.1 - 4.8e-37 126.6 10.3 6.7e-37 126.1 1.5 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF53933.1 - 2.9e-30 104.8 14.1 1.9e-27 95.7 3.2 4.1 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF53933.1 - 1.1e-25 90.6 0.6 4.5e-25 88.6 0.0 2.5 3 1 0 3 3 3 1 Multicopper oxidase C1q PF00386.21 OWF53933.1 - 0.037 14.2 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 C1q domain HSP70 PF00012.20 OWF53934.1 - 5.9e-10 38.0 0.0 1.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein DDR PF08841.10 OWF53934.1 - 0.00051 19.1 0.3 0.034 13.1 0.1 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Peptidase_M22 PF00814.25 OWF53934.1 - 0.15 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family HSP70 PF00012.20 OWF53935.1 - 3.6e-09 35.4 0.0 0.00016 20.0 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein DDR PF08841.10 OWF53935.1 - 0.00013 21.1 0.1 0.055 12.5 0.0 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Ribonuc_2-5A PF06479.12 OWF53935.1 - 0.082 13.1 0.4 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease 2-5A HSP70 PF00012.20 OWF53936.1 - 5.4e-07 28.2 0.0 0.0005 18.4 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein DDR PF08841.10 OWF53936.1 - 0.0016 17.5 0.2 0.044 12.8 0.0 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain p450 PF00067.22 OWF53937.1 - 9.3e-60 202.7 0.0 1.1e-59 202.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Snf7 PF03357.21 OWF53937.1 - 0.29 10.7 0.6 9 5.9 0.0 2.1 1 1 1 2 2 2 0 Snf7 HSP70 PF00012.20 OWF53938.1 - 0.011 14.0 0.1 1.9 6.6 0.1 2.2 2 0 0 2 2 2 0 Hsp70 protein Tho2 PF11262.8 OWF53939.1 - 1.9e-101 339.2 6.4 1.9e-101 339.2 6.4 4.7 4 2 1 5 5 5 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 OWF53939.1 - 4.5e-81 273.4 0.1 1.1e-56 192.8 0.8 6.5 3 2 2 5 5 5 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 OWF53939.1 - 1.1e-35 121.5 0.0 3.1e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit TPR_19 PF14559.6 OWF53939.1 - 0.012 16.1 0.1 0.063 13.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.6 OWF53940.1 - 2.5e-22 80.0 0.0 4.8e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 OWF53940.1 - 5.8e-11 42.9 0.0 1.5e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 OWF53940.1 - 1.4e-08 34.4 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.6 OWF53940.1 - 4.7e-08 33.6 0.0 1.7e-07 31.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OWF53940.1 - 2.1e-06 27.7 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 OWF53940.1 - 0.0018 18.1 0.0 0.0074 16.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF53940.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OWF53940.1 - 0.022 15.5 0.7 0.12 13.1 0.2 2.5 2 1 0 2 2 1 0 Methyltransferase domain RRM_5 PF13893.6 OWF53940.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy PF03171.20 OWF53940.1 - 0.063 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RRM_occluded PF16842.5 OWF53940.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf-C2H2 PF00096.26 OWF53941.1 - 3e-26 90.4 67.2 0.00033 20.9 0.2 9.8 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF53941.1 - 2.3e-24 84.7 65.8 2.4e-05 24.5 0.2 10.5 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF53941.1 - 1.4e-23 81.5 62.7 0.0016 19.1 0.5 9.9 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF53941.1 - 4.7e-13 48.8 52.8 1.1e-06 28.5 2.3 8.0 8 1 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF53941.1 - 5.8e-11 42.4 45.3 0.099 13.0 0.8 9.4 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF53941.1 - 4.7e-06 26.8 48.4 0.019 15.3 2.4 9.4 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF53941.1 - 6e-05 23.3 44.5 0.00072 19.8 1.7 5.7 3 1 3 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OWF53941.1 - 0.011 15.5 1.0 0.011 15.5 1.0 6.6 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 OWF53941.1 - 0.019 14.7 0.9 0.019 14.7 0.9 7.0 7 1 0 7 7 7 0 C2H2-type zinc-finger domain PHF5 PF03660.14 OWF53941.1 - 0.044 14.0 0.5 0.044 14.0 0.5 4.0 1 1 2 4 4 4 0 PHF5-like protein zf-C2H2_2 PF12756.7 OWF53941.1 - 0.16 12.3 39.5 12 6.3 10.7 6.5 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) SOCS_box PF07525.16 OWF53942.1 - 4.3e-12 46.2 1.1 9.2e-12 45.1 1.1 1.5 1 0 0 1 1 1 1 SOCS box Ank PF00023.30 OWF53942.1 - 0.0088 16.5 0.0 0.033 14.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OWF53942.1 - 0.091 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ACR_tran PF00873.19 OWF53942.1 - 0.15 9.6 0.0 0.22 9.1 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TOBE_2 PF08402.10 OWF53943.1 - 0.11 12.6 20.7 1.6 8.9 0.1 6.7 1 1 6 7 7 7 0 TOBE domain DUF1656 PF07869.12 OWF53944.1 - 1.2 9.2 77.2 6.7 6.8 1.6 14.9 1 1 13 15 15 15 0 Protein of unknown function (DUF1656) LRR_4 PF12799.7 OWF53944.1 - 2.2 8.8 50.8 14 6.2 0.5 9.9 1 1 7 8 8 8 0 Leucine Rich repeats (2 copies) adh_short_C2 PF13561.6 OWF53945.1 - 4.3e-60 203.2 0.8 5.5e-60 202.8 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF53945.1 - 2.3e-50 170.8 0.9 3.2e-50 170.3 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF53945.1 - 1e-07 32.1 0.2 1.5e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OWF53945.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 OWF53945.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OWF53945.1 - 0.054 12.6 0.3 0.094 11.8 0.3 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 OWF53946.1 - 1.6e-60 204.6 0.4 1.8e-60 204.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF53946.1 - 6.8e-50 169.2 1.6 9.7e-50 168.7 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF53946.1 - 1.9e-08 34.4 0.5 3e-08 33.8 0.5 1.3 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 OWF53947.1 - 7.6e-59 199.4 0.0 9.6e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF53947.1 - 2.2e-05 25.4 0.0 7.5e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fez1 PF06818.15 OWF53949.1 - 0.0032 17.9 12.8 0.0032 17.9 12.8 2.5 2 1 0 2 2 2 1 Fez1 WD40_alt PF14077.6 OWF53949.1 - 0.34 10.8 4.8 0.14 12.0 0.6 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif Bcr-Abl_Oligo PF09036.10 OWF53949.1 - 0.8 9.8 4.7 1.9 8.6 0.4 2.6 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF641 PF04859.12 OWF53949.1 - 1.8 8.9 18.1 0.1 13.0 4.1 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) GAS PF13851.6 OWF53950.1 - 0.00033 20.1 17.2 0.00033 20.1 17.2 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 OWF53950.1 - 0.00063 18.7 12.2 0.0014 17.6 12.2 1.5 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 OWF53950.1 - 0.0011 17.9 14.6 0.0011 17.9 14.6 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein HAP1_N PF04849.13 OWF53950.1 - 0.0012 18.1 14.6 0.0024 17.1 14.6 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ING PF12998.7 OWF53950.1 - 0.0033 18.0 9.3 0.37 11.4 4.8 3.2 2 1 1 3 3 2 2 Inhibitor of growth proteins N-terminal histone-binding HemX PF04375.14 OWF53950.1 - 0.0057 16.0 2.3 0.0057 16.0 2.3 3.2 2 1 1 3 3 3 1 HemX, putative uroporphyrinogen-III C-methyltransferase UPF0242 PF06785.11 OWF53950.1 - 0.006 16.7 8.9 0.006 16.7 8.9 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 OWF53950.1 - 0.0078 16.5 13.1 0.0078 16.5 13.1 3.8 4 0 0 4 4 3 1 Autophagy protein 16 (ATG16) Filament PF00038.21 OWF53950.1 - 0.035 13.7 15.9 0.18 11.4 15.5 2.3 1 1 1 2 2 2 0 Intermediate filament protein Cep57_MT_bd PF06657.13 OWF53950.1 - 0.14 12.6 9.6 2.6 8.6 2.2 2.7 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Prominin PF05478.11 OWF53950.1 - 0.2 9.6 11.1 0.19 9.6 9.7 1.5 1 1 0 1 1 1 0 Prominin Atg14 PF10186.9 OWF53950.1 - 0.21 10.6 15.6 0.35 9.9 14.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 OWF53950.1 - 0.24 10.3 4.3 0.34 9.8 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4509 PF14970.6 OWF53950.1 - 0.33 10.9 6.6 0.7 9.8 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) EzrA PF06160.12 OWF53950.1 - 0.52 8.4 19.0 0.096 10.8 15.1 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 OWF53950.1 - 0.61 9.6 16.7 0.045 13.3 10.9 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit SKA2 PF16740.5 OWF53950.1 - 1.7 8.4 15.9 8 6.3 7.6 2.8 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Laminin_II PF06009.12 OWF53950.1 - 2 8.4 20.0 0.47 10.5 5.8 2.9 2 1 1 3 3 3 0 Laminin Domain II APG6_N PF17675.1 OWF53950.1 - 2.5 8.6 27.6 0.8 10.2 18.5 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF2203 PF09969.9 OWF53950.1 - 3.1 8.5 12.4 2.4 8.9 2.9 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.8 OWF53950.1 - 4.9 6.4 17.1 1.6 7.9 7.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Laminin_I PF06008.14 OWF53950.1 - 5.2 6.7 21.9 2.5 7.8 17.3 2.5 2 1 0 2 2 1 0 Laminin Domain I IFT57 PF10498.9 OWF53950.1 - 7.1 5.5 25.9 0.0078 15.2 13.1 2.3 2 0 0 2 2 1 0 Intra-flagellar transport protein 57 TMPIT PF07851.13 OWF53950.1 - 7.2 5.8 19.1 4.9 6.3 6.9 2.4 1 1 2 3 3 3 0 TMPIT-like protein MnmE_helical PF12631.7 OWF53951.1 - 3.2e-52 177.7 2.4 4.9e-52 177.1 2.4 1.3 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 OWF53951.1 - 2.1e-34 118.3 0.0 1.8e-33 115.3 0.0 2.4 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 OWF53951.1 - 1.5e-21 76.6 0.1 3.5e-21 75.4 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF53951.1 - 3.1e-09 36.5 0.3 2.9e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OWF53951.1 - 3.2e-09 36.9 1.8 0.00022 21.2 0.1 3.1 2 1 1 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 OWF53951.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1_Xtn PF16897.5 OWF53951.1 - 0.0011 19.0 0.9 0.0074 16.3 0.2 2.5 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MCM PF00493.23 OWF53951.1 - 0.0044 16.1 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 OWF53951.1 - 0.014 15.8 0.1 0.044 14.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OWF53951.1 - 0.045 13.5 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 OWF53951.1 - 0.052 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GBP PF02263.19 OWF53951.1 - 0.095 11.9 0.3 0.47 9.7 0.2 2.2 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain LRR_8 PF13855.6 OWF53952.1 - 4.9e-34 115.9 30.7 1.1e-13 50.7 1.2 6.2 2 2 6 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OWF53952.1 - 6.5e-14 51.8 26.6 2.6e-05 24.5 0.8 6.2 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF53952.1 - 3.9e-11 43.1 0.1 1e-10 41.7 0.1 1.8 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF53952.1 - 1.4e-09 38.6 0.2 3.4e-09 37.3 0.2 1.7 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 OWF53952.1 - 8.7e-07 28.7 10.5 19 6.3 0.0 8.3 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_5 PF13306.6 OWF53952.1 - 0.00025 21.0 7.7 0.00062 19.7 2.4 2.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 OWF53952.1 - 0.0072 16.0 3.1 0.0072 16.0 3.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 OWF53952.1 - 0.0072 15.8 5.6 0.066 12.7 0.7 3.2 2 1 1 3 3 3 2 Leucine-rich repeat TPKR_C2 PF16920.5 OWF53952.1 - 0.032 14.4 0.6 0.032 14.4 0.6 2.6 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Fn_bind PF02986.14 OWF53953.1 - 2.9e-06 26.9 25.2 31 4.4 0.0 12.3 13 1 1 14 14 14 4 Fibronectin binding repeat Bap31 PF05529.12 OWF53953.1 - 0.23 11.3 11.7 8.8 6.2 0.3 4.3 1 1 3 6 6 6 0 Bap31/Bap29 transmembrane region Peptidase_C14 PF00656.22 OWF53954.1 - 1e-10 42.0 0.5 1.4e-10 41.6 0.5 1.1 1 0 0 1 1 1 1 Caspase domain Mpp10 PF04006.12 OWF53955.1 - 9.1e-177 589.2 108.3 9.3e-155 516.5 89.0 2.0 1 1 1 2 2 2 2 Mpp10 protein Perilipin PF03036.16 OWF53956.1 - 6.1e-66 223.1 4.6 8e-66 222.7 4.6 1.0 1 0 0 1 1 1 1 Perilipin family Opi1 PF08618.10 OWF53956.1 - 8.7e-05 21.9 0.1 0.00031 20.1 0.0 1.8 2 0 0 2 2 2 1 Transcription factor Opi1 Ima1_N PF09779.9 OWF53956.1 - 0.18 12.7 5.5 9 7.2 0.1 3.0 3 0 0 3 3 3 0 Ima1 N-terminal domain Syntaxin_2 PF14523.6 OWF53956.1 - 0.34 11.3 3.5 2.1 8.8 0.4 3.5 2 2 1 3 3 3 0 Syntaxin-like protein CLZ PF16526.5 OWF53956.1 - 1.2 9.5 5.8 0.41 11.1 0.5 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoO PF09769.9 OWF53956.1 - 1.6 8.7 4.4 25 4.8 0.1 3.7 2 2 2 4 4 4 0 Apolipoprotein O ApoLp-III PF07464.11 OWF53956.1 - 6.8 6.8 8.2 15 5.7 0.6 3.0 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FKBP_C PF00254.28 OWF53957.1 - 5.8e-30 103.5 0.0 1.9e-29 101.8 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 OWF53957.1 - 1.1e-23 83.8 0.1 1.1e-23 83.8 0.1 3.4 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 OWF53957.1 - 0.0042 17.6 1.0 0.29 11.6 0.0 2.7 2 0 0 2 2 2 1 Nucleoplasmin/nucleophosmin domain YL1 PF05764.13 OWF53957.1 - 0.92 9.6 53.7 0.082 13.0 30.6 2.2 1 1 1 2 2 2 0 YL1 nuclear protein Hamartin PF04388.12 OWF53957.1 - 3.5 6.2 15.1 4.6 5.8 15.1 1.1 1 0 0 1 1 1 0 Hamartin protein Endosulfine PF04667.17 OWF53958.1 - 9.7e-11 41.7 5.3 2.2e-10 40.5 5.3 1.7 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Neur_chan_LBD PF02931.23 OWF53959.1 - 5.2e-46 156.8 0.7 7.9e-46 156.2 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF53959.1 - 4.8e-22 79.2 5.5 1.4e-20 74.4 0.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.22 OWF53960.1 - 5.2e-31 107.4 0.0 6.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF53960.1 - 2.6e-11 43.8 0.0 3.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF53960.1 - 0.00076 19.0 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF53960.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF53960.1 - 0.023 15.0 0.0 0.1 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OWF53960.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OWF53960.1 - 0.15 11.2 0.1 2.9 6.9 0.0 2.0 1 1 0 2 2 2 0 G-protein alpha subunit 7tm_1 PF00001.21 OWF53961.1 - 1.7e-49 168.5 16.3 2.1e-49 168.2 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF53961.1 - 1.7e-13 50.5 20.3 2.4e-13 50.1 20.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF53961.1 - 2.6e-09 37.1 23.9 1.1e-08 35.1 23.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF53961.1 - 2.7e-07 30.2 22.1 8.1e-07 28.6 22.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srab PF10292.9 OWF53961.1 - 9e-05 21.5 4.1 9e-05 21.5 4.1 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor IPTL-CTERM PF18203.1 OWF53962.1 - 0.44 10.5 0.1 0.44 10.5 0.1 2.0 3 0 0 3 3 3 0 IPTL-CTERM motif DUF4446 PF14584.6 OWF53966.1 - 0.0054 16.7 9.4 2.7 8.0 0.1 4.6 4 0 0 4 4 4 3 Protein of unknown function (DUF4446) YtxH PF12732.7 OWF53966.1 - 0.71 10.4 9.5 1.2 9.7 4.2 3.5 2 1 1 3 3 3 0 YtxH-like protein Laminin_II PF06009.12 OWF53966.1 - 2.4 8.1 11.7 11 6.0 0.5 3.5 3 1 0 3 3 3 0 Laminin Domain II RRM_1 PF00076.22 OWF53967.1 - 1.7e-23 82.2 0.5 6.6e-09 35.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TUDOR PF00567.24 OWF53967.1 - 1.3e-13 51.0 0.0 3.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Tudor domain OST-HTH PF12872.7 OWF53967.1 - 8.9e-12 44.7 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain RRM_5 PF13893.6 OWF53967.1 - 0.061 12.9 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF53967.1 - 0.11 12.4 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif UCH PF00443.29 OWF53968.1 - 8.5e-62 209.0 0.1 1.5e-61 208.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF53968.1 - 4.4e-26 92.2 0.0 9.1e-25 87.9 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OWF53968.1 - 2.6e-18 66.1 15.3 2.6e-18 66.1 15.3 3.3 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Vps54 PF07928.12 OWF53968.1 - 0.15 12.5 0.1 6.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Vps54-like protein FKBP_C PF00254.28 OWF53969.1 - 1.3e-13 51.1 0.1 5.8e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 OWF53969.1 - 2.9e-13 49.0 0.0 0.006 16.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF53969.1 - 6.2e-09 35.3 0.0 0.0062 16.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF53969.1 - 1.8e-06 27.5 0.0 0.12 12.0 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 OWF53969.1 - 1.3e-05 25.0 1.8 0.005 16.9 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF53969.1 - 0.00013 22.3 0.0 0.0021 18.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF53969.1 - 0.00025 21.6 0.2 0.076 13.9 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF53969.1 - 0.00029 21.4 0.7 0.015 15.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF53969.1 - 0.00053 20.2 0.0 0.077 13.3 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF53969.1 - 0.0011 18.8 0.0 0.13 12.3 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat Macoilin PF09726.9 OWF53969.1 - 0.0074 14.9 11.8 0.014 14.0 11.8 1.4 1 1 0 1 1 1 1 Macoilin family ANAPC3 PF12895.7 OWF53969.1 - 0.033 14.4 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 OWF53969.1 - 0.06 13.4 0.4 0.89 9.7 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 OWF53969.1 - 0.074 13.5 0.0 0.074 13.5 0.0 1.8 2 0 0 2 2 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 OWF53969.1 - 0.095 13.4 0.5 4.3 8.2 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 OWF53969.1 - 2.8 8.0 6.6 19 5.3 4.0 2.3 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RRM_1 PF00076.22 OWF53970.1 - 4.3e-17 61.7 0.0 7.7e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prenyltrans PF00432.21 OWF53971.1 - 3e-39 132.4 15.9 2.1e-10 40.2 0.0 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Ski_Sno PF02437.17 OWF53972.1 - 4.1e-36 123.0 0.4 1.1e-35 121.7 0.4 1.7 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 OWF53972.1 - 7.6e-31 106.2 6.0 7.6e-31 106.2 6.0 2.2 2 0 0 2 2 2 1 c-SKI Smad4 binding domain PSP PF04046.16 OWF53973.1 - 0.025 14.4 0.2 63 3.6 0.0 5.1 1 1 2 5 5 5 0 PSP DUF2990 PF11693.8 OWF53973.1 - 0.28 11.4 4.4 89 3.4 0.1 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2990) EF-hand_1 PF00036.32 OWF53974.1 - 1.2e-09 37.0 8.0 0.0023 17.4 1.6 4.1 2 2 2 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF53974.1 - 2.1e-08 33.4 6.6 0.087 12.8 0.2 4.0 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF53974.1 - 7e-07 28.5 4.5 0.0025 17.3 0.1 3.7 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OWF53974.1 - 4.3e-06 27.1 8.6 0.29 11.6 0.1 3.6 1 1 2 4 4 4 3 EF-hand domain pair WIYLD PF10440.9 OWF53974.1 - 0.003 17.3 0.1 0.008 16.0 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain EF-hand_8 PF13833.6 OWF53974.1 - 0.034 14.0 1.4 3.4 7.6 0.2 3.2 2 1 1 3 3 3 0 EF-hand domain pair Dockerin_1 PF00404.18 OWF53974.1 - 0.075 13.2 1.1 5.2 7.3 0.4 2.9 3 0 0 3 3 3 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 OWF53974.1 - 0.15 12.3 1.7 8.4 6.8 0.2 2.4 1 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Gal-bind_lectin PF00337.22 OWF53975.1 - 8.6e-79 261.6 1.6 2.3e-38 130.7 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin WIF PF02019.18 OWF53975.1 - 0.22 11.2 0.2 12 5.5 0.0 2.4 2 0 0 2 2 2 0 WIF domain Gal-bind_lectin PF00337.22 OWF53976.1 - 2.4e-38 130.7 0.2 2.6e-38 130.6 0.2 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin AAA_2 PF07724.14 OWF53977.1 - 2.7e-39 135.0 0.1 4.9e-39 134.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OWF53977.1 - 4.9e-14 52.9 0.1 1.1e-13 51.8 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OWF53977.1 - 9.5e-11 41.6 0.0 2.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OWF53977.1 - 3.6e-05 23.8 0.0 9.5e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OWF53977.1 - 0.00025 20.8 0.0 0.0011 18.7 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 OWF53977.1 - 0.0015 18.8 0.2 0.014 15.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OWF53977.1 - 0.0022 17.8 0.0 0.007 16.1 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OWF53977.1 - 0.006 16.0 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OWF53977.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OWF53977.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OWF53977.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF53977.1 - 0.093 13.1 0.3 0.27 11.6 0.2 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 OWF53977.1 - 0.094 13.3 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 OWF53977.1 - 0.11 11.9 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Isopentenyl transferase PhnA_Zn_Ribbon PF08274.12 OWF53977.1 - 0.14 12.1 2.5 0.9 9.6 0.5 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DNA_ligase_ZBD PF03119.16 OWF53977.1 - 0.21 11.6 0.6 0.49 10.5 0.6 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Arm PF00514.23 OWF53978.1 - 9.3e-08 31.9 7.3 0.24 11.5 0.0 6.1 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 OWF53978.1 - 0.00046 20.2 6.2 0.022 14.8 1.2 4.4 3 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 OWF53978.1 - 0.00072 19.5 4.7 0.0043 17.0 0.7 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) TFCD_C PF12612.8 OWF53978.1 - 0.042 13.7 1.1 0.49 10.2 0.3 2.7 1 1 0 2 2 2 0 Tubulin folding cofactor D C terminal HTH_47 PF16221.5 OWF53978.1 - 0.11 12.0 0.1 0.39 10.3 0.1 1.9 1 0 0 1 1 1 0 winged helix-turn-helix V-ATPase_H_C PF11698.8 OWF53978.1 - 5.1 7.3 6.0 18 5.5 0.6 3.4 2 1 2 4 4 4 0 V-ATPase subunit H DUF4239 PF14023.6 OWF53979.1 - 4.6e-09 36.3 1.7 7.4e-09 35.6 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Trypan_PARP PF05887.11 OWF53980.1 - 0.0021 18.0 3.0 0.0034 17.3 3.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4239 PF14023.6 OWF53980.1 - 0.083 12.6 1.2 0.36 10.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) TonB_N PF16031.5 OWF53980.1 - 0.98 9.9 6.5 1.5 9.4 6.5 1.2 1 0 0 1 1 1 0 TonB polyproline region MccV PF17508.2 OWF53982.1 - 0.025 15.1 0.3 0.031 14.8 0.3 1.2 1 0 0 1 1 1 0 Microcin V bacteriocin TraT PF05818.12 OWF53982.1 - 0.033 13.9 0.6 0.038 13.7 0.6 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Wzz PF02706.15 OWF53982.1 - 0.06 13.7 0.2 0.23 11.8 0.1 1.8 2 0 0 2 2 2 0 Chain length determinant protein TAFH PF07531.14 OWF53982.1 - 0.062 13.4 1.2 0.24 11.6 0.3 2.0 2 0 0 2 2 2 0 NHR1 homology to TAF YtzH PF14165.6 OWF53982.1 - 0.067 13.6 0.6 0.49 10.8 0.0 2.2 2 1 0 2 2 2 0 YtzH-like protein PAH PF02671.21 OWF53982.1 - 0.32 11.2 3.2 1.6 8.9 0.3 2.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat Gly-zipper_Omp PF13488.6 OWF53982.1 - 0.67 10.0 15.8 1.4 9.0 15.8 1.5 1 1 0 1 1 1 0 Glycine zipper DUF3482 PF11981.8 OWF53982.1 - 1.2 8.5 5.7 2 7.7 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) Ldl_recept_a PF00057.18 OWF53983.1 - 4e-69 228.5 199.2 1.4e-11 44.4 5.0 13.2 12 1 1 13 13 13 12 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 OWF53983.1 - 1.7e-33 114.1 23.5 2.2e-16 59.4 0.9 3.3 1 1 2 3 3 3 3 Leucine rich repeat 7tm_1 PF00001.21 OWF53983.1 - 5.6e-28 98.0 14.5 9.4e-28 97.3 14.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 OWF53983.1 - 7.5e-10 38.9 16.4 0.00013 22.2 0.2 4.4 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF53983.1 - 5.3e-06 26.0 3.3 0.017 14.6 0.9 2.3 1 1 1 2 2 2 2 Leucine-rich repeat 7TM_GPCR_Srsx PF10320.9 OWF53983.1 - 5.6e-05 22.7 11.9 9.4e-05 21.9 11.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_1 PF00560.33 OWF53983.1 - 0.037 14.5 13.8 20 6.2 0.0 6.6 6 0 0 6 6 6 0 Leucine Rich Repeat OAD_gamma PF04277.13 OWF53983.1 - 0.16 12.6 0.2 0.37 11.4 0.2 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain 7tm_4 PF13853.6 OWF53983.1 - 0.54 9.9 11.4 1.7 8.3 11.4 1.7 1 1 0 1 1 1 0 Olfactory receptor ETC_C1_NDUFA4 PF04800.12 OWF53985.1 - 5.4e-37 125.9 1.4 7.5e-37 125.5 1.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF4573 PF15140.6 OWF53986.1 - 9.8e-05 22.2 0.0 0.48 10.2 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) ATP_Ca_trans_C PF12424.8 OWF53986.1 - 1.3 9.5 2.9 3.2e+02 1.9 2.9 5.4 1 1 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal Sema PF01403.19 OWF53987.1 - 2.4e-128 428.6 0.1 2.4e-128 428.6 0.1 1.7 2 0 0 2 2 2 1 Sema domain PSI PF01437.25 OWF53987.1 - 0.038 14.5 3.5 0.13 12.9 3.5 1.9 1 0 0 1 1 1 0 Plexin repeat zf-primase PF09329.11 OWF53987.1 - 0.047 13.5 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 Primase zinc finger COMM_domain PF07258.14 OWF53988.1 - 7.8e-19 67.6 2.0 7.8e-19 67.6 2.0 1.9 2 0 0 2 2 2 1 COMM domain Nup188_C PF18378.1 OWF53988.1 - 0.0024 16.8 1.7 0.003 16.4 1.7 1.1 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain ATP_bind_1 PF03029.17 OWF53989.1 - 2.9e-87 292.4 0.2 3.9e-87 292.0 0.2 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 OWF53989.1 - 0.00036 20.5 0.1 0.01 15.8 0.0 2.4 1 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OWF53989.1 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 OWF53989.1 - 0.0029 16.6 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 OWF53989.1 - 0.0067 15.8 0.0 0.33 10.3 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.6 OWF53989.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 OWF53989.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_17 PF13207.6 OWF53989.1 - 0.028 14.9 1.0 0.63 10.5 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OWF53989.1 - 0.034 14.7 1.7 0.34 11.5 0.6 2.9 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OWF53989.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF53989.1 - 0.057 13.8 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OWF53989.1 - 0.098 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OWF53989.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OWF53989.1 - 0.17 12.0 0.1 3.8 7.6 0.0 2.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OWF53989.1 - 0.21 11.7 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4490 PF14892.6 OWF53990.1 - 0.054 13.5 6.4 3.4 7.8 0.8 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4490) CRF PF00473.17 OWF53990.1 - 0.32 11.1 3.4 69 3.6 0.0 3.7 1 1 3 4 4 4 0 Corticotropin-releasing factor family DUF4490 PF14892.6 OWF53991.1 - 0.00091 19.2 11.2 1.5 8.9 1.0 4.6 1 1 3 4 4 4 4 Domain of unknown function (DUF4490) UTP15_C PF09384.10 OWF53993.1 - 1e-42 145.3 1.0 1.7e-42 144.6 1.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OWF53993.1 - 2.4e-23 82.0 9.2 0.00067 20.4 0.0 7.5 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF53993.1 - 5.3e-12 45.9 0.1 0.026 14.8 0.0 5.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF53993.1 - 1.5e-05 24.5 0.0 0.00023 20.6 0.0 2.1 1 1 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 OWF53993.1 - 0.014 14.0 0.9 1.1 7.7 0.0 2.9 1 1 1 3 3 3 0 Cytochrome D1 heme domain Formyl_trans_C PF02911.18 OWF53993.1 - 0.015 15.5 0.0 2.1 8.7 0.0 3.1 3 0 0 3 3 3 0 Formyl transferase, C-terminal domain ARID PF01388.21 OWF53994.1 - 7.3e-22 77.8 0.3 2.7e-21 76.0 0.1 2.1 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain Spatacsin_C PF14649.6 OWF53996.1 - 5.9e-96 321.2 6.1 1e-95 320.4 2.6 2.7 3 0 0 3 3 3 1 Spatacsin C-terminus FliT PF05400.13 OWF53996.1 - 3.6 8.5 4.9 43 5.0 0.6 3.5 2 1 1 3 3 3 0 Flagellar protein FliT FHA PF00498.26 OWF53997.1 - 1e-16 61.0 0.0 2.4e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain OCRE PF17780.1 OWF53997.1 - 1.1e-15 57.3 22.2 1.1e-15 57.3 22.2 2.6 2 0 0 2 2 2 1 OCRE domain G-patch PF01585.23 OWF53997.1 - 1.3e-13 50.6 0.6 3e-13 49.4 0.6 1.6 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 OWF53997.1 - 6.7e-08 32.7 0.0 2.1e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain G-patch_2 PF12656.7 OWF53997.1 - 2.3e-06 27.6 0.2 1.1e-05 25.4 0.2 2.3 1 0 0 1 1 1 1 G-patch domain WW PF00397.26 OWF53997.1 - 0.01 15.9 3.7 0.01 15.9 3.7 3.1 2 1 0 2 2 2 0 WW domain DMPK_coil PF08826.10 OWF53997.1 - 0.013 15.6 3.5 0.013 15.6 3.5 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like Pentapeptide_4 PF13599.6 OWF53998.1 - 5.4e-43 145.0 48.6 2.5e-08 34.0 2.1 7.9 1 1 8 9 9 9 9 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 OWF53998.1 - 4.7e-19 67.7 32.8 0.0043 16.7 0.5 10.5 5 3 3 10 10 10 9 Pentapeptide repeats (8 copies) Pertus-S4-tox PF09275.10 OWF53998.1 - 1e-07 32.2 8.9 36 4.7 0.0 10.0 1 1 11 13 13 13 2 Pertussis toxin S4 subunit Pentapeptide_4 PF13599.6 OWF53999.1 - 6.9e-07 29.3 4.5 5.4e-05 23.3 1.3 2.7 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 OWF53999.1 - 0.033 13.8 0.6 15 5.4 0.1 3.2 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OWF54000.1 - 4.4e-22 78.0 14.4 9.5e-08 32.1 1.9 3.3 1 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 OWF54000.1 - 9.9e-11 41.1 11.6 0.061 13.0 0.5 5.6 3 2 3 6 6 6 5 Pentapeptide repeats (8 copies) Pertus-S4-tox PF09275.10 OWF54000.1 - 1.3e-06 28.6 0.2 2.5 8.4 0.0 5.1 1 1 4 5 5 5 2 Pertussis toxin S4 subunit Pentapeptide_3 PF13576.6 OWF54000.1 - 0.00043 20.4 5.1 0.93 9.7 0.2 4.1 2 2 1 3 3 3 2 Pentapeptide repeats (9 copies) DUF713 PF05218.14 OWF54000.1 - 0.18 11.5 10.9 15 5.3 0.2 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF713) RhgB_N PF09284.10 OWF54000.1 - 0.22 11.0 9.1 2.4 7.6 0.6 3.6 1 1 1 3 3 3 0 Rhamnogalacturonan lyase B, N-terminal SLM4 PF16818.5 OWF54000.1 - 6.6 6.7 8.9 47 3.9 1.1 3.6 1 1 2 3 3 3 0 Protein SLM4 Kazal_2 PF07648.15 OWF54001.1 - 5.8e-20 71.2 27.8 4.2e-10 39.6 4.3 4.7 5 0 0 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF54001.1 - 1.9e-13 50.2 43.2 1.8e-06 27.9 7.4 4.4 4 1 0 4 4 4 3 Kazal-type serine protease inhibitor domain Adeno_E4 PF05385.11 OWF54001.1 - 0.028 14.5 1.5 0.028 14.5 1.5 2.9 3 0 0 3 3 3 0 Mastadenovirus early E4 13 kDa protein FOLN PF09289.10 OWF54001.1 - 1.1 9.5 22.1 0.12 12.5 5.2 4.1 3 0 0 3 3 3 0 Follistatin/Osteonectin-like EGF domain Linker_histone PF00538.19 OWF54002.1 - 7.8e-23 80.6 0.7 7.8e-23 80.6 0.7 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family RE_AlwI PF09491.10 OWF54002.1 - 0.027 13.3 3.1 0.031 13.1 3.1 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease Hid1 PF12722.7 OWF54002.1 - 6.9 4.7 6.5 7.1 4.6 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_2 PF12796.7 OWF54003.1 - 1.6e-14 54.2 0.1 1.4e-07 32.0 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF54003.1 - 6e-14 51.9 1.0 8.6e-06 25.9 0.1 5.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF54003.1 - 3.3e-10 40.3 3.3 1.9e-05 25.1 0.1 6.8 7 2 2 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF54003.1 - 4.4e-08 33.2 0.1 0.0059 17.0 0.1 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 OWF54003.1 - 3.3e-06 27.0 2.8 0.029 14.9 0.1 6.3 7 0 0 7 7 7 1 Ankyrin repeat LPMO_10 PF03067.15 OWF54004.1 - 1e-32 114.4 0.2 2.2e-32 113.3 0.2 1.6 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ammonium_transp PF00909.21 OWF54005.1 - 1.6e-95 320.2 28.4 1.9e-95 319.9 28.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Collagen PF01391.18 OWF54006.1 - 1.5e-26 91.9 61.1 6.4e-09 35.4 17.9 3.8 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.6 OWF54007.1 - 4.9e-69 228.3 197.8 3.4e-08 33.6 11.4 12.4 12 0 0 12 12 12 10 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF54007.1 - 3.7e-54 180.2 106.9 5.5e-08 32.6 2.1 11.9 11 0 0 11 11 11 10 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF54007.1 - 2.3e-50 168.5 184.6 1.1e-07 31.9 10.3 12.3 12 0 0 12 12 12 12 Calcium-binding EGF domain EGF PF00008.27 OWF54007.1 - 1.8e-17 63.3 183.2 0.0077 16.5 9.1 13.2 12 1 0 12 12 12 10 EGF-like domain hEGF PF12661.7 OWF54007.1 - 0.0037 17.9 11.2 0.012 16.3 0.7 15.7 14 6 0 14 14 14 5 Human growth factor-like EGF EGF_3 PF12947.7 OWF54007.1 - 0.0056 16.8 4.0 0.0056 16.8 4.0 15.2 8 6 3 13 13 13 5 EGF domain Plasmod_Pvs28 PF06247.11 OWF54007.1 - 0.021 15.1 6.6 0.021 15.1 6.6 12.2 6 5 5 12 12 12 0 Pvs28 EGF domain Calx-beta PF03160.14 OWF54008.1 - 7.3e-77 253.9 39.0 4.7e-10 39.5 0.6 13.6 14 0 0 14 14 14 12 Calx-beta domain Laminin_G_3 PF13385.6 OWF54008.1 - 5e-19 68.9 0.3 2e-18 67.0 0.3 2.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OWF54008.1 - 2.9e-07 31.1 0.0 6.9e-06 26.7 0.0 3.2 3 0 0 3 3 3 1 Laminin G domain SCP2_2 PF13530.6 OWF54008.1 - 0.0072 16.7 0.2 11 6.4 0.0 3.5 4 0 0 4 4 4 2 Sterol carrier protein domain Lectin_C PF00059.21 OWF54009.1 - 1.1e-14 55.0 3.0 2.1e-14 54.1 3.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain Calx-beta PF03160.14 OWF54010.1 - 2.3e-61 204.2 39.2 1.3e-10 41.4 0.1 12.7 12 2 0 12 12 12 10 Calx-beta domain DUF4843 PF16132.5 OWF54010.1 - 0.0014 18.3 0.0 26 4.4 0.0 4.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4843) VRR_NUC PF08774.11 OWF54011.1 - 1e-20 73.8 0.0 3.8e-20 72.0 0.0 2.0 1 0 0 1 1 1 1 VRR-NUC domain TPR_6 PF13174.6 OWF54011.1 - 1.8 9.3 4.2 9 7.2 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Death PF00531.22 OWF54012.1 - 0.0015 18.6 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 Death domain DUF4639 PF15479.6 OWF54012.1 - 1.9 7.4 12.9 2.5 7.0 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) adh_short PF00106.25 OWF54013.1 - 1.6e-32 112.5 3.9 1.5e-28 99.6 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF54013.1 - 1e-16 61.2 0.0 1.6e-16 60.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 7tm_1 PF00001.21 OWF54014.1 - 1.7e-19 70.2 20.7 2.2e-19 69.8 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-C4 PF00105.18 OWF54015.1 - 0.0037 17.7 34.4 6 7.4 0.3 7.2 6 1 0 7 7 7 5 Zinc finger, C4 type (two domains) zf-C4_ClpX PF06689.13 OWF54015.1 - 0.023 14.6 18.8 7.2 6.6 0.1 6.4 6 1 0 6 6 6 0 ClpX C4-type zinc finger DUF3510 PF12022.8 OWF54015.1 - 0.026 14.9 15.3 2.8 8.3 0.3 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF3510) zf-A20 PF01754.16 OWF54015.1 - 0.038 13.9 27.3 0.64 10.0 0.2 7.4 7 0 0 7 7 7 0 A20-like zinc finger C1_2 PF03107.16 OWF54015.1 - 0.049 14.0 46.1 1.7 9.0 0.1 6.9 4 3 3 7 7 7 0 C1 domain CxC7 PF18866.1 OWF54015.1 - 0.16 12.1 16.5 22 5.3 0.1 6.1 6 0 0 6 6 6 0 CxC7 like cysteine cluster associated with KDZ transposases zf-HIT PF04438.16 OWF54015.1 - 1.2 9.1 19.5 18 5.3 0.1 6.9 7 0 0 7 7 7 0 HIT zinc finger ProRS-C_1 PF09180.11 OWF54015.1 - 1.4 9.2 9.0 97 3.3 0.0 5.0 5 1 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Apolipoprotein PF01442.18 OWF54017.1 - 0.00011 22.2 23.3 0.022 14.6 7.2 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Laminin_G_2 PF02210.24 OWF54018.1 - 0.013 16.1 1.3 0.45 11.1 1.3 2.2 1 1 0 1 1 1 0 Laminin G domain DUF3379 PF11859.8 OWF54018.1 - 0.041 13.2 9.7 0.13 11.6 5.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3379) Phage_TTP_13 PF16463.5 OWF54018.1 - 0.065 12.8 0.3 7.3 6.1 0.1 2.4 1 1 1 2 2 2 0 Phage tail tube protein family Csm1_B PF18211.1 OWF54018.1 - 0.1 12.4 1.1 0.5 10.2 0.3 2.3 1 1 2 3 3 3 0 Csm1 subunit domain B DUF150_C PF17384.2 OWF54018.1 - 0.17 12.0 3.2 4 7.7 0.2 3.2 1 1 3 4 4 4 0 RimP C-terminal SH3 domain Laminin_G_1 PF00054.23 OWF54018.1 - 0.24 11.6 2.4 2 8.6 2.3 2.3 1 1 0 1 1 1 0 Laminin G domain CppA_N PF14506.6 OWF54018.1 - 0.46 10.6 4.7 1.1 9.3 0.6 2.2 1 1 1 2 2 2 0 CppA N-terminal ELL PF10390.9 OWF54018.1 - 1.3 8.4 7.5 1.7e+02 1.5 7.5 2.6 1 1 0 1 1 1 0 RNA polymerase II elongation factor ELL DAP_B PF07930.12 OWF54018.1 - 2.1 8.3 4.6 2.7 7.9 2.7 1.9 1 1 1 2 2 2 0 D-aminopeptidase, domain B DUF4412 PF14371.6 OWF54018.1 - 3.7 7.3 13.6 3.4 7.4 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4412) NADH_dehy_S2_C PF06444.11 OWF54018.1 - 4.5 7.9 15.3 3.9 8.0 3.6 3.1 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus zf_C2H2_ZHX PF18387.1 OWF54018.1 - 8.3 6.1 10.6 24 4.7 0.7 3.5 2 1 3 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain Ependymin PF00811.18 OWF54019.1 - 4.5e-16 59.3 0.6 1.2e-15 57.9 0.3 1.7 2 0 0 2 2 2 1 Ependymin Transglut_core PF01841.19 OWF54020.1 - 0.00058 20.3 0.0 0.0039 17.6 0.0 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF1891 PF09004.10 OWF54020.1 - 0.052 13.1 0.3 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) Transglut_core PF01841.19 OWF54021.1 - 0.019 15.4 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF4211 PF13926.6 OWF54021.1 - 0.16 12.0 0.8 7.7 6.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4211) Transglut_core PF01841.19 OWF54022.1 - 0.0024 18.3 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Big_3_4 PF13754.6 OWF54022.1 - 0.046 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Transglut_core PF01841.19 OWF54023.1 - 0.00055 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Swi5 PF07061.11 OWF54023.1 - 6.3 7.0 11.0 0.27 11.3 1.0 2.5 2 0 0 2 2 2 0 Swi5 Transglut_core PF01841.19 OWF54024.1 - 0.00093 19.6 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2141 PF09912.9 OWF54025.1 - 0.002 18.0 0.1 0.006 16.5 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) BBS2_C PF14782.6 OWF54025.1 - 0.0054 15.6 0.2 0.0089 14.8 0.2 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Transglut_core PF01841.19 OWF54025.1 - 0.015 15.8 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily GPI-anchored PF10342.9 OWF54025.1 - 0.19 12.5 2.1 0.41 11.4 0.8 2.2 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Lsm_C PF14894.6 OWF54026.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Lsm C-terminal adh_short PF00106.25 OWF54027.1 - 2.7e-47 160.7 1.0 2.7e-47 160.7 1.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF54027.1 - 4.9e-36 124.4 0.1 6.3e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF54027.1 - 4.6e-06 26.7 0.1 8.9e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OWF54027.1 - 0.0031 17.0 0.1 0.0063 15.9 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OWF54027.1 - 0.024 14.1 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 OWF54027.1 - 0.053 12.8 0.2 0.27 10.5 0.1 1.8 2 0 0 2 2 2 0 P-loop ATPase protein family VHP PF02209.19 OWF54027.1 - 0.17 12.0 0.9 0.83 9.8 0.2 2.2 2 0 0 2 2 2 0 Villin headpiece domain adh_short PF00106.25 OWF54028.1 - 3.8e-47 160.3 1.3 5.1e-47 159.9 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF54028.1 - 1.1e-35 123.3 0.1 1.4e-35 123.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF54028.1 - 4e-06 26.9 0.1 1.2e-05 25.4 0.1 1.6 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 OWF54028.1 - 0.003 17.0 0.1 0.0066 15.9 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ATP_bind_2 PF03668.15 OWF54028.1 - 0.0048 16.2 0.2 0.067 12.5 0.1 2.0 2 0 0 2 2 2 1 P-loop ATPase protein family Epimerase PF01370.21 OWF54028.1 - 0.031 13.7 0.2 0.048 13.1 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF853 PF05872.12 OWF54028.1 - 0.04 12.5 0.2 1.6 7.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) VHP PF02209.19 OWF54028.1 - 0.12 12.5 1.1 0.48 10.5 0.3 2.1 2 0 0 2 2 2 0 Villin headpiece domain PTS_2-RNA PF01885.16 OWF54029.1 - 2.6e-15 56.9 0.0 2.9e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Tti2 PF10521.9 OWF54031.1 - 1.1e-11 44.8 2.4 1.5e-11 44.3 0.1 2.3 2 1 0 2 2 2 1 Tti2 family MRG PF05712.13 OWF54032.1 - 1.5e-51 174.6 0.2 1.5e-51 174.6 0.2 3.4 2 1 0 2 2 2 1 MRG Tudor-knot PF11717.8 OWF54032.1 - 7.6e-16 57.7 1.2 7.6e-16 57.7 1.2 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain TFIIF_alpha PF05793.12 OWF54032.1 - 0.00036 19.3 84.1 0.00051 18.8 84.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VWA PF00092.28 OWF54033.1 - 2.3e-15 57.3 0.0 5.5e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF54033.1 - 1.7e-13 51.1 0.0 4.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain WWE PF02825.20 OWF54033.1 - 7.2e-09 36.1 0.2 2.1e-08 34.6 0.2 1.9 1 0 0 1 1 1 1 WWE domain MIB_HERC2 PF06701.13 OWF54033.1 - 2.8e-06 27.5 0.2 0.002 18.3 0.0 3.3 4 0 0 4 4 4 2 Mib_herc2 Transglut_core PF01841.19 OWF54034.1 - 0.0036 17.7 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1024 PF06260.12 OWF54034.1 - 0.15 12.3 0.0 3.1 8.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1024) LRR_8 PF13855.6 OWF54035.1 - 1.6e-11 43.8 8.3 4.4e-07 29.6 3.7 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF54035.1 - 1.2e-07 31.9 10.5 0.0013 19.1 2.7 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF54035.1 - 9.4e-05 22.3 0.1 0.00016 21.5 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 OWF54035.1 - 0.00033 20.2 2.8 0.062 12.8 0.4 2.3 2 0 0 2 2 2 2 Leucine-rich repeat LRRNT PF01462.18 OWF54035.1 - 0.014 15.0 3.1 0.014 15.0 3.1 2.8 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain TIR_2 PF13676.6 OWF54035.1 - 0.021 15.4 0.0 0.043 14.4 0.0 1.5 1 0 0 1 1 1 0 TIR domain LRR_5 PF13306.6 OWF54035.1 - 0.065 13.2 2.1 0.3 11.0 1.3 2.3 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 OWF54035.1 - 0.38 10.9 13.0 3.1 8.1 0.4 6.2 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 OWF54035.1 - 3.7 8.5 11.2 32 5.6 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat DUF2859 PF11072.8 OWF54036.1 - 0.19 11.5 1.0 2.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) DUF4512 PF14975.6 OWF54037.1 - 2.9e-10 40.8 5.7 4.7e-10 40.1 5.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) RIO1 PF01163.22 OWF54038.1 - 9e-49 165.6 0.1 1.8e-48 164.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OWF54038.1 - 1.3e-30 105.5 0.1 2.6e-30 104.5 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 OWF54038.1 - 4.1e-07 29.6 0.2 2.6e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF54038.1 - 1.2e-06 28.7 1.8 0.011 15.7 0.5 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OWF54038.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Menin PF05053.13 OWF54038.1 - 4.6 5.5 16.5 6.9 4.9 16.5 1.2 1 0 0 1 1 1 0 Menin Serinc PF03348.15 OWF54039.1 - 2.9e-125 418.6 22.2 4.5e-125 418.0 22.2 1.2 1 1 0 1 1 1 1 Serine incorporator (Serinc) TPMT PF05724.11 OWF54040.1 - 1.6e-28 99.9 0.1 2e-28 99.6 0.1 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 OWF54040.1 - 0.091 13.4 0.0 0.73 10.5 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain TPMT PF05724.11 OWF54041.1 - 1.2e-27 97.0 0.0 1.5e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 OWF54041.1 - 0.13 12.9 0.0 1.1 10.0 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain An_peroxidase PF03098.15 OWF54042.1 - 1.6e-138 462.6 0.0 2.4e-138 462.0 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 OWF54042.1 - 1.4e-29 103.2 0.0 3.6e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OWF54042.1 - 5.7e-18 65.0 0.0 1.5e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OWF54042.1 - 9.9e-14 51.5 17.4 2.5e-13 50.2 17.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 OWF54042.1 - 1.3e-07 30.6 3.8 0.0002 20.7 0.9 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OWF54042.1 - 1.3e-06 28.8 6.6 1.4e-05 25.4 1.1 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF54042.1 - 9.9e-05 22.0 3.0 0.16 11.9 0.6 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OWF54042.1 - 0.0003 20.6 7.5 0.017 15.0 0.7 3.8 4 0 0 4 4 4 2 EF-hand domain pair NAD_binding_1 PF00175.21 OWF54042.1 - 0.00074 20.1 0.0 0.0052 17.4 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain GrpE PF01025.19 OWF54042.1 - 1.7 8.3 6.8 0.068 12.8 0.2 1.9 2 0 0 2 2 2 0 GrpE CENP-H PF05837.12 OWF54044.1 - 1.1e-19 70.9 3.2 1.1e-19 70.9 3.2 2.2 2 1 0 2 2 2 1 Centromere protein H (CENP-H) SL4P PF17618.2 OWF54044.1 - 0.016 15.2 0.6 0.055 13.5 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized Strongylid L4 protein FliJ PF02050.16 OWF54044.1 - 2.9 8.1 13.6 8 6.7 4.3 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein zf-C2H2 PF00096.26 OWF54045.1 - 2.2e-12 46.7 39.9 0.0088 16.5 2.7 6.8 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF54045.1 - 2.1e-10 40.5 36.5 0.051 14.4 1.7 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OWF54045.1 - 7.2e-08 32.7 20.6 1 9.7 0.1 7.4 3 2 4 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OWF54045.1 - 0.00071 19.9 14.6 11 6.6 0.1 6.1 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 OWF54045.1 - 0.0028 17.2 1.7 3.3 7.4 0.0 3.6 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 OWF54045.1 - 0.007 16.2 13.1 0.41 10.5 0.1 4.7 3 1 1 4 4 4 1 GAGA factor Actin_micro PF17003.5 OWF54045.1 - 0.014 14.6 5.2 0.36 9.9 0.0 3.5 3 1 0 3 3 3 0 Putative actin-like family zf-Di19 PF05605.12 OWF54045.1 - 0.015 15.6 25.6 0.017 15.4 0.4 4.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OWF54045.1 - 0.025 14.9 7.3 8.1 6.9 0.3 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF54045.1 - 0.22 11.6 16.9 0.85 9.7 0.5 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OWF54045.1 - 0.93 9.2 20.3 0.15 11.8 0.4 5.8 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain Mif2_N PF15624.6 OWF54045.1 - 1.5 9.5 8.0 3.8 8.2 6.5 2.7 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF629 PF04780.12 OWF54045.1 - 3.6 6.0 9.2 2 6.9 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF629) TBCA PF02970.16 OWF54046.1 - 1.3e-32 111.9 9.9 1.6e-32 111.6 9.9 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Helo_like_N PF17111.5 OWF54046.1 - 0.0069 15.8 0.6 0.0069 15.8 0.6 1.5 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 OWF54046.1 - 0.033 14.2 0.4 0.033 14.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 OWF54046.1 - 0.044 12.4 5.7 0.051 12.2 5.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 OWF54046.1 - 0.099 12.9 7.2 0.16 12.2 7.2 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4355 PF14265.6 OWF54046.1 - 0.22 11.8 13.3 3.5 7.9 13.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) EGF_CA PF07645.15 OWF54047.1 - 1.3e-08 34.9 10.9 1.3e-08 34.9 10.9 3.1 3 0 0 3 3 3 1 Calcium-binding EGF domain EGF_3 PF12947.7 OWF54047.1 - 6.9e-06 26.2 2.9 6.9e-06 26.2 2.9 3.1 2 1 1 3 3 3 1 EGF domain FXa_inhibition PF14670.6 OWF54047.1 - 0.0017 18.6 10.7 0.0088 16.3 8.6 2.5 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF54047.1 - 0.022 14.7 2.6 0.022 14.7 2.6 2.8 2 1 0 2 2 2 0 Complement Clr-like EGF-like Ig_3 PF13927.6 OWF54048.1 - 2e-21 76.3 0.0 1.4e-10 41.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF54048.1 - 3.1e-18 65.6 0.0 9.6e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 OWF54048.1 - 3.4e-18 65.6 0.0 3.5e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF54048.1 - 5.2e-14 52.3 0.1 9.2e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF54048.1 - 1.4e-11 44.5 0.3 6.5e-05 23.1 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF54048.1 - 4.6e-05 23.4 0.0 0.031 14.3 0.0 2.4 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 OWF54048.1 - 4.8e-05 23.7 0.9 0.25 11.8 0.2 3.4 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Herpes_gE PF02480.16 OWF54048.1 - 0.00067 18.5 0.0 0.047 12.5 0.0 2.0 1 1 0 2 2 2 2 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 OWF54048.1 - 0.0007 19.1 0.4 0.36 10.4 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 OWF54048.1 - 0.0014 18.8 0.7 1.6 9.0 0.0 3.4 2 1 1 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_3 PF13927.6 OWF54049.1 - 6.7e-22 77.9 0.4 1.9e-09 38.0 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF54049.1 - 1.7e-20 72.9 0.3 1.1e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 OWF54049.1 - 3.5e-18 65.5 1.0 2.1e-08 34.2 0.3 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF54049.1 - 6.4e-14 52.0 1.0 1.1e-07 31.9 0.3 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF54049.1 - 5.7e-12 45.8 0.2 2.6e-06 27.7 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 OWF54049.1 - 0.00033 20.2 0.0 0.8 9.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 OWF54049.1 - 0.00056 20.1 0.6 3.7 7.9 0.0 3.6 2 2 1 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 OWF54049.1 - 0.00081 19.4 0.4 1.5 8.9 0.2 2.6 2 1 0 2 2 2 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 OWF54049.1 - 0.0019 18.5 0.6 0.13 12.7 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin C1-set domain TIR_2 PF13676.6 OWF54050.1 - 1.2e-23 84.0 0.1 3.1e-23 82.6 0.1 1.8 1 1 0 1 1 1 1 TIR domain V-ATPase_H_N PF03224.14 OWF54050.1 - 0.00036 19.9 0.3 0.00099 18.5 0.1 1.8 2 0 0 2 2 2 1 V-ATPase subunit H TIR PF01582.20 OWF54050.1 - 0.0025 17.6 0.1 0.0096 15.7 0.1 2.0 1 0 0 1 1 1 1 TIR domain XisI PF08869.11 OWF54050.1 - 0.022 15.1 1.0 0.054 13.8 0.6 1.8 2 0 0 2 2 2 0 XisI protein Glyco_hydro_80 PF13647.6 OWF54050.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 80 of chitosanase A Methyltransf_21 PF05050.12 OWF54050.1 - 0.22 11.5 0.7 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase FkbM domain DUF1282 PF06930.12 OWF54051.1 - 0.00022 21.1 1.0 0.00022 21.1 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1282) 7tm_2 PF00002.24 OWF54052.1 - 3.9e-10 39.4 14.4 5.3e-10 39.0 14.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 OWF54052.1 - 6.7e-10 38.6 14.6 9.3e-10 38.1 14.6 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Amidase02_C PF12123.8 OWF54052.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Otopetrin PF03189.13 OWF54052.1 - 0.17 10.7 9.1 0.64 8.8 7.5 2.0 2 0 0 2 2 2 0 Otopetrin MSP1a PF11670.8 OWF54053.1 - 0.14 11.5 1.1 0.2 10.9 1.1 1.1 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) 7tm_1 PF00001.21 OWF54054.1 - 7.7e-53 179.5 11.0 1e-52 179.1 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF54054.1 - 2.8e-13 49.8 10.4 4.2e-13 49.3 10.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF54054.1 - 7.4e-05 22.6 8.9 0.0014 18.4 9.2 2.1 2 0 0 2 2 2 1 Olfactory receptor DUF4031 PF13223.6 OWF54055.1 - 0.0021 18.3 2.0 10 6.4 0.2 3.7 1 1 2 3 3 3 2 Protein of unknown function (DUF4031) Antimicrobial18 PF08130.11 OWF54055.1 - 0.0024 17.9 2.9 2.1 8.5 0.3 3.7 1 1 2 3 3 3 1 Type A lantibiotic family ASFV_J13L PF05568.11 OWF54055.1 - 0.088 12.6 0.7 6.5 6.5 0.1 2.3 1 1 1 2 2 2 0 African swine fever virus J13L protein zf-CCCH_6 PF18585.1 OWF54055.1 - 0.09 12.7 15.7 14 5.7 0.1 5.7 1 1 4 5 5 5 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 zf-ACC PF17848.1 OWF54055.1 - 4 7.6 16.7 1.1e+02 3.0 0.1 6.1 6 1 0 6 6 6 0 Acetyl-coA carboxylase zinc finger domain Helicase_C PF00271.31 OWF54056.1 - 3.9e-07 30.4 0.0 4.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OWF54057.1 - 3.7e-15 56.1 0.3 3.7e-15 56.1 0.3 4.5 4 2 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OWF54057.1 - 2.6e-12 47.1 0.0 7.6e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OWF54057.1 - 6.1e-11 42.5 0.1 2.4e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OWF54057.1 - 5.4e-06 26.3 0.8 0.00011 22.0 0.8 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OWF54057.1 - 0.0021 18.3 3.3 0.0026 18.1 0.2 2.5 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 OWF54057.1 - 0.034 14.1 0.3 0.19 11.7 0.2 2.3 1 1 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 OWF54057.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OWF54057.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF86 PF01934.17 OWF54058.1 - 0.017 15.0 0.6 0.043 13.7 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF86 ADIP PF11559.8 OWF54058.1 - 0.049 13.7 22.5 1.4 9.0 11.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TUDOR PF00567.24 OWF54058.1 - 0.071 13.1 1.2 1 9.4 0.0 3.2 4 0 0 4 4 4 0 Tudor domain MCC-bdg_PDZ PF10506.9 OWF54058.1 - 0.074 13.1 0.2 0.074 13.1 0.2 2.4 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APOBEC_C PF05240.14 OWF54058.1 - 0.16 11.9 1.9 8.7 6.4 0.2 3.4 2 1 1 3 3 3 0 APOBEC-like C-terminal domain BLOC1_2 PF10046.9 OWF54058.1 - 0.55 10.6 9.3 0.49 10.7 1.7 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_15 PF13175.6 OWF54058.1 - 6.7 6.3 18.9 9.9 5.7 18.7 1.4 1 1 0 1 1 1 0 AAA ATPase domain ZapB PF06005.12 OWF54058.1 - 8.3 6.9 22.6 1.9 9.0 6.5 3.1 2 1 0 2 2 2 0 Cell division protein ZapB Death PF00531.22 OWF54059.1 - 4.4e-05 23.5 0.0 9.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Death domain DED PF01335.21 OWF54059.1 - 0.0078 16.5 0.2 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 Death effector domain eIF3_subunit PF08597.10 OWF54060.1 - 2.5e-52 178.2 30.2 2.8e-52 178.0 30.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ARL2_Bind_BART PF11527.8 OWF54060.1 - 1.5 9.0 9.4 0.23 11.6 5.4 1.7 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART FAM221 PF14753.6 OWF54061.1 - 1.6e-24 86.6 10.9 7.8e-17 61.5 1.8 2.1 2 0 0 2 2 2 2 Protein FAM221A/B Aldedh PF00171.22 OWF54062.1 - 1.2e-180 601.0 0.0 1.4e-180 600.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PorP_SprF PF11751.8 OWF54063.1 - 0.013 15.0 15.9 0.015 14.9 15.9 1.1 1 0 0 1 1 1 0 Type IX secretion system membrane protein PorP/SprF LRR_8 PF13855.6 OWF54065.1 - 9.4e-18 63.7 36.2 1.5e-08 34.2 6.7 5.7 4 2 1 5 5 5 3 Leucine rich repeat TIR PF01582.20 OWF54065.1 - 1.7e-13 50.7 2.8 7.7e-12 45.4 2.8 2.4 1 1 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF54065.1 - 4.7e-10 39.5 39.3 0.00086 19.6 5.1 7.1 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 OWF54065.1 - 1.2e-06 29.2 0.2 2.4e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 TIR domain LRRNT PF01462.18 OWF54065.1 - 0.0033 17.0 1.6 0.012 15.3 1.6 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 OWF54065.1 - 0.029 13.9 10.0 0.16 11.5 1.9 3.0 2 1 1 3 3 3 0 Leucine-rich repeat Phenol_MetA_deg PF13557.6 OWF54065.1 - 0.28 11.1 2.5 0.44 10.4 2.5 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation Cadherin_3 PF16184.5 OWF54066.1 - 8.2e-208 676.2 52.8 3.1e-28 98.0 0.1 15.4 15 0 0 15 15 15 15 Cadherin-like Laminin_G_2 PF02210.24 OWF54066.1 - 9.3e-47 158.7 10.8 3.2e-25 89.1 0.1 5.1 5 0 0 5 5 5 2 Laminin G domain Laminin_G_1 PF00054.23 OWF54066.1 - 6.8e-40 136.3 1.1 2.9e-21 76.1 0.0 3.0 2 0 0 2 2 2 2 Laminin G domain Cadherin_4 PF17803.1 OWF54066.1 - 0.0013 19.3 21.8 1.9 9.2 1.9 7.8 8 0 0 8 8 8 1 Bacterial cadherin-like domain Cadherin_5 PF17892.1 OWF54066.1 - 0.0089 16.0 3.0 10 6.2 0.4 4.6 4 0 0 4 4 4 2 Cadherin-like domain DUF3827 PF12877.7 OWF54066.1 - 0.014 13.8 0.5 0.06 11.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) TMEM154 PF15102.6 OWF54066.1 - 0.028 14.3 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 OWF54066.1 - 0.055 13.4 0.5 0.22 11.5 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Plasmod_Pvs28 PF06247.11 OWF54066.1 - 0.074 13.4 1.3 0.15 12.4 1.3 1.5 1 0 0 1 1 1 0 Pvs28 EGF domain DUF4448 PF14610.6 OWF54066.1 - 0.11 12.3 0.1 0.35 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 OWF54066.1 - 0.21 11.0 6.3 0.41 10.1 6.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF PF00008.27 OWF54066.1 - 0.32 11.3 4.4 0.61 10.5 4.4 1.4 1 0 0 1 1 1 0 EGF-like domain Band_7_C PF16200.5 OWF54067.1 - 1.3e-29 102.0 2.3 3.8e-29 100.5 2.3 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7 PF01145.25 OWF54067.1 - 2.2e-28 99.4 0.2 2.2e-28 99.4 0.2 2.1 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OWF54067.1 - 0.017 14.9 0.5 0.034 13.9 0.1 1.7 2 0 0 2 2 2 0 SPFH domain-Band 7 family Ion_trans PF00520.31 OWF54068.1 - 0.0068 15.7 2.5 0.01 15.1 2.5 1.1 1 0 0 1 1 1 1 Ion transport protein UPF0225 PF17775.1 OWF54068.1 - 0.025 15.4 2.5 0.86 10.5 0.1 2.2 2 0 0 2 2 2 0 UPF0225 domain G-gamma PF00631.22 OWF54068.1 - 0.035 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 GGL domain Fib_alpha PF08702.10 OWF54068.1 - 0.05 13.8 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CDK2AP PF09806.9 OWF54068.1 - 1.1 9.3 4.6 2 8.4 0.4 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SlyX PF04102.12 OWF54068.1 - 1.2 9.9 2.9 0.6 10.8 0.2 1.9 2 0 0 2 2 2 0 SlyX ADP_PFK_GK PF04587.15 OWF54069.1 - 1.8e-117 392.5 0.0 2e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region peroxidase PF00141.23 OWF54069.1 - 0.049 13.3 0.1 1.2 8.7 0.0 2.4 1 1 0 2 2 2 0 Peroxidase Tom37 PF10568.9 OWF54070.1 - 6.6e-28 97.5 0.0 1.1e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 OWF54070.1 - 2.3e-19 68.9 1.8 2.6e-19 68.8 0.1 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF54070.1 - 9.6e-15 55.1 0.0 2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 OWF54070.1 - 0.0096 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NS3_envE PF02723.14 OWF54070.1 - 0.081 13.0 0.4 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Peptidase_C14 PF00656.22 OWF54071.1 - 2.4e-19 70.3 0.0 4.4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Ig_3 PF13927.6 OWF54071.1 - 3e-16 59.8 0.3 2.1e-09 37.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 OWF54071.1 - 4.2e-14 52.6 1.8 4.3e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF54071.1 - 4e-13 49.2 0.1 3.2e-08 33.5 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain MALT1_Ig PF18703.1 OWF54071.1 - 8.6e-11 42.0 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 MALT1 Ig-like domain Ig_5 PF16681.5 OWF54071.1 - 2.1e-05 24.9 0.3 0.19 12.2 0.0 2.5 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.25 OWF54071.1 - 2.8e-05 24.2 1.7 0.00011 22.3 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 OWF54071.1 - 8.3e-05 22.8 2.6 0.43 10.9 0.0 2.6 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 OWF54071.1 - 0.0005 19.6 0.7 0.029 13.9 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 OWF54071.1 - 0.0024 18.0 5.5 0.02 15.0 0.1 3.5 2 2 2 4 4 4 1 Immunoglobulin V-set domain ICAM_N PF03921.14 OWF54071.1 - 0.14 11.8 1.0 0.3 10.8 1.0 1.5 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain EGF_CA PF07645.15 OWF54071.1 - 3.3 8.0 4.9 2.5 8.4 0.2 2.7 3 0 0 3 3 2 0 Calcium-binding EGF domain Arrestin_N PF00339.29 OWF54072.1 - 1e-37 129.4 0.2 1.3e-35 122.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF54072.1 - 1.1e-23 84.1 0.0 1.3e-18 67.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 OWF54072.1 - 0.00078 18.5 0.0 0.0018 17.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Pro_isomerase PF00160.21 OWF54073.1 - 5.4e-40 137.2 0.3 6.9e-40 136.9 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myosin_head PF00063.21 OWF54074.1 - 2e-53 181.7 0.0 3.4e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Chitin_synth_2 PF03142.15 OWF54074.1 - 2.5e-30 105.6 0.0 2.5e-30 105.6 0.0 2.6 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF54074.1 - 2.6e-10 40.5 1.8 2.6e-10 40.5 1.8 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF54074.1 - 1.2e-08 35.1 0.1 3.7e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF54074.1 - 0.00026 20.8 0.0 0.00094 19.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OWF54074.1 - 0.0011 18.4 0.0 0.0054 16.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Myosin_head PF00063.21 OWF54075.1 - 6.1e-169 563.4 0.3 8.6e-169 562.9 0.3 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Chitin_synth_2 PF03142.15 OWF54075.1 - 1e-32 113.5 1.8 1e-28 100.3 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF54075.1 - 7.1e-12 45.6 1.4 7.1e-12 45.6 1.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF54075.1 - 9.3e-10 38.8 0.0 2.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF54075.1 - 0.00014 21.7 1.6 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OWF54075.1 - 0.0012 18.4 0.2 0.036 13.5 0.2 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.6 OWF54075.1 - 0.029 14.6 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OWF54075.1 - 0.034 14.5 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 OWF54075.1 - 0.06 13.1 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OWF54075.1 - 0.14 12.6 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Alk_phosphatase PF00245.20 OWF54076.1 - 3.5e-132 441.3 0.0 4e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF54076.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily 7tm_1 PF00001.21 OWF54077.1 - 8.2e-17 61.4 12.7 1.1e-16 60.9 12.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF54077.1 - 4.6e-08 32.7 12.6 8e-06 25.4 12.6 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF54077.1 - 5.7e-06 26.2 8.8 1.2e-05 25.1 8.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.13 OWF54077.1 - 0.00021 20.5 10.5 0.00049 19.3 10.5 1.6 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) DUF2157 PF09925.9 OWF54077.1 - 0.38 10.5 6.5 0.97 9.2 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) PAP2 PF01569.21 OWF54078.1 - 2.6e-18 66.1 0.7 2.6e-18 66.1 0.7 2.5 2 1 1 3 3 3 1 PAP2 superfamily MFS_MOT1 PF16983.5 OWF54078.1 - 0.12 12.8 3.9 0.1 13.0 1.1 2.3 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Rgp1 PF08737.10 OWF54079.1 - 2.2e-44 152.3 2.4 3.9e-22 79.0 0.2 2.7 2 1 1 3 3 3 2 Rgp1 Arrestin_N PF00339.29 OWF54079.1 - 0.032 14.3 0.5 0.067 13.2 0.0 1.9 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Linker_histone PF00538.19 OWF54080.1 - 8.3e-22 77.4 0.2 8.3e-22 77.4 0.2 3.0 3 1 0 3 3 3 1 linker histone H1 and H5 family Kelch_6 PF13964.6 OWF54081.1 - 4.3e-41 137.9 1.4 1.2e-07 31.8 0.0 7.3 6 1 1 7 7 7 6 Kelch motif Kelch_2 PF07646.15 OWF54081.1 - 7.4e-38 127.1 3.4 8.9e-07 28.6 0.0 7.3 7 0 0 7 7 7 7 Kelch motif Kelch_1 PF01344.25 OWF54081.1 - 2.8e-32 110.0 10.3 1.6e-06 27.6 0.0 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_4 PF13418.6 OWF54081.1 - 2.8e-30 104.1 13.9 1.6e-06 28.0 0.0 7.1 5 1 2 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OWF54081.1 - 6.4e-29 99.4 0.4 0.00078 19.4 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 OWF54081.1 - 1.4e-27 95.4 9.0 2.5e-07 30.8 0.0 6.8 6 2 0 6 6 6 5 Galactose oxidase, central domain F-box PF00646.33 OWF54082.1 - 5.2e-06 26.2 0.0 2.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OWF54082.1 - 1.5e-05 24.8 0.0 4.1e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like IBN_N PF03810.19 OWF54083.1 - 5.6e-16 58.2 0.7 2.5e-14 52.9 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OWF54083.1 - 0.0083 16.2 2.0 0.031 14.3 0.3 3.1 3 0 0 3 3 3 1 Exportin 1-like protein Cation_efflux PF01545.21 OWF54084.1 - 4.2e-50 170.2 10.4 4.2e-50 170.2 10.4 2.8 2 1 0 2 2 2 1 Cation efflux family DUF3097 PF11296.8 OWF54086.1 - 0.18 11.0 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) F-box-like PF12937.7 OWF54087.1 - 1e-07 31.7 5.4 2.5e-07 30.5 5.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF54087.1 - 1.7e-07 30.9 4.8 3.8e-07 29.8 4.8 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 OWF54087.1 - 0.00024 21.8 1.9 0.001 19.9 0.3 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat PRANC PF09372.10 OWF54087.1 - 0.083 13.2 1.7 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Pkinase_Tyr PF07714.17 OWF54088.1 - 4.5e-87 291.6 0.0 5.9e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 OWF54088.1 - 2.5e-45 152.4 1.0 1.4e-24 86.0 0.1 2.8 3 0 0 3 3 3 2 SH2 domain Pkinase PF00069.25 OWF54088.1 - 4.6e-43 147.5 0.0 7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 OWF54088.1 - 9.3e-14 50.8 0.0 2.4e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF54088.1 - 1.3e-09 37.7 0.0 4.1e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF54088.1 - 3.1e-09 36.4 0.0 9.2e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 OWF54088.1 - 0.00027 20.9 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family hSH3 PF14603.6 OWF54088.1 - 0.0025 18.2 0.0 0.0067 16.8 0.0 1.7 1 0 0 1 1 1 1 Helically-extended SH3 domain Kinase-like PF14531.6 OWF54088.1 - 0.0044 16.4 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SH2_2 PF14633.6 OWF54088.1 - 0.016 14.6 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 SH2 domain Pkinase_fungal PF17667.1 OWF54088.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Drf_FH1 PF06346.12 OWF54089.1 - 2.3e-06 27.4 74.3 0.042 13.6 11.7 5.1 1 1 4 5 5 5 4 Formin Homology Region 1 Abhydrolase_2 PF02230.16 OWF54089.1 - 0.046 13.5 0.0 1.1e+02 2.4 0.0 4.5 2 1 1 5 5 5 0 Phospholipase/Carboxylesterase Lipocalin_2 PF08212.12 OWF54090.1 - 3.5e-14 53.0 0.0 4.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF54090.1 - 0.0011 19.2 0.1 0.002 18.4 0.1 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family 7tm_1 PF00001.21 OWF54091.1 - 1.8e-17 63.5 22.4 2.3e-17 63.2 22.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF54091.1 - 1.1e-10 41.3 21.1 7.1e-10 38.7 21.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 OWF54091.1 - 0.046 13.1 22.8 0.19 11.1 22.8 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx FAST_2 PF08368.12 OWF54092.1 - 9.4e-05 23.1 0.1 0.00026 21.7 0.1 1.7 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 Nterm_IS4 PF13006.7 OWF54092.1 - 0.057 13.6 0.0 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal HNF-1A_C PF04813.12 OWF54093.1 - 0.013 16.3 0.0 56 4.6 0.0 4.3 1 1 3 5 5 5 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF5460 PF17544.2 OWF54093.1 - 3.8 6.4 6.8 55 2.6 0.1 3.9 2 1 0 4 4 4 0 Family of unknown function (DUF5460) HNF-1A_C PF04813.12 OWF54094.1 - 2.4e-05 25.0 0.0 13 6.6 0.0 4.5 3 2 1 5 5 5 3 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Ank_2 PF12796.7 OWF54095.1 - 4.6e-27 94.4 6.5 4.6e-12 46.4 0.3 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF54095.1 - 6.3e-20 71.3 1.8 4.5e-06 27.1 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF54095.1 - 6.7e-20 70.9 2.7 6.3e-11 42.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF54095.1 - 3.2e-12 45.5 0.3 0.0046 17.4 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OWF54095.1 - 7.5e-12 45.1 1.2 0.00042 20.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat SKI PF01202.22 OWF54096.1 - 5e-14 52.7 0.0 1.6e-13 51.1 0.0 1.7 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OWF54096.1 - 2.9e-09 37.6 0.0 4.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 OWF54096.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.6 OWF54096.1 - 0.00025 21.3 0.0 0.0004 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF54096.1 - 0.00042 20.5 0.0 0.001 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OWF54096.1 - 0.00051 20.5 1.0 0.0025 18.2 1.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 OWF54096.1 - 0.00072 20.0 0.1 0.0027 18.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OWF54096.1 - 0.0037 17.0 0.2 0.0084 15.9 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase CPT PF07931.12 OWF54096.1 - 0.0064 16.3 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 OWF54096.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 OWF54096.1 - 0.017 15.2 0.0 0.045 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OWF54096.1 - 0.02 15.1 0.1 0.066 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 OWF54096.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain PRK PF00485.18 OWF54096.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.9 OWF54096.1 - 0.023 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 OWF54096.1 - 0.024 15.0 0.2 0.097 13.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 OWF54096.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OWF54096.1 - 0.047 13.5 0.0 0.097 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system tRNA_lig_kinase PF08303.11 OWF54096.1 - 0.052 13.6 0.0 0.57 10.3 0.0 2.3 2 1 0 2 2 2 0 tRNA ligase kinase domain dNK PF01712.19 OWF54096.1 - 0.068 13.0 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 OWF54096.1 - 0.071 13.0 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 OWF54096.1 - 0.098 13.2 0.4 0.13 12.7 0.4 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OWF54096.1 - 0.099 12.4 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF54096.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 OWF54096.1 - 0.11 12.1 0.0 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase FERM_M PF00373.18 OWF54097.1 - 4.7e-19 68.9 0.0 2.2e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 OWF54097.1 - 3.4e-18 65.8 0.1 6.3e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 OWF54097.1 - 2.8e-15 56.0 0.1 9.3e-15 54.3 0.1 1.9 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 OWF54097.1 - 1.4e-10 41.0 1.2 4.5e-10 39.4 1.2 2.0 1 0 0 1 1 1 1 FERM adjacent (FA) DUF1518 PF07469.12 OWF54097.1 - 1.5 9.3 6.7 12 6.4 3.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) SRCR PF00530.18 OWF54098.1 - 4.9e-170 553.2 53.1 1.3e-27 96.3 0.4 9.1 9 0 0 9 9 9 9 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF54098.1 - 2.8e-33 114.3 30.9 0.00013 22.4 0.4 9.5 9 0 0 9 9 9 8 Scavenger receptor cysteine-rich domain CUB PF00431.20 OWF54098.1 - 1.3e-11 44.8 0.0 3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 CUB domain Hepsin-SRCR PF09272.10 OWF54098.1 - 9.3e-07 29.4 9.2 16 6.0 0.1 8.2 8 0 0 8 8 8 1 Hepsin, SRCR domain Defensin_1 PF00323.19 OWF54098.1 - 0.7 10.5 3.2 55 4.4 0.2 3.9 3 0 0 3 3 3 0 Mammalian defensin Prok-RING_1 PF14446.6 OWF54098.1 - 2.6 8.1 10.2 10 6.1 0.0 6.0 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 SRCR PF00530.18 OWF54099.1 - 4e-125 409.1 41.0 2.3e-25 89.0 2.6 8.1 8 0 0 8 8 8 8 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF54099.1 - 1.2e-22 80.3 28.7 0.0001 22.8 0.4 7.6 7 1 0 7 7 7 6 Scavenger receptor cysteine-rich domain CUB PF00431.20 OWF54099.1 - 5.7e-12 45.9 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 CUB domain Hepsin-SRCR PF09272.10 OWF54099.1 - 0.0023 18.4 8.8 38 4.9 0.0 6.5 6 0 0 6 6 6 0 Hepsin, SRCR domain Ribosomal_S27e PF01667.17 OWF54099.1 - 0.037 13.7 0.2 0.21 11.3 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Jiraiya PF15038.6 OWF54100.1 - 2.4e-44 150.8 10.4 3.3e-44 150.3 10.4 1.2 1 0 0 1 1 1 1 Jiraiya DUF2207 PF09972.9 OWF54100.1 - 0.0039 16.0 1.9 0.041 12.7 0.0 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) DUF3147 PF11345.8 OWF54100.1 - 0.063 13.6 0.5 0.063 13.6 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) 2TM PF13239.6 OWF54100.1 - 0.16 12.3 0.1 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 2TM domain DHHC PF01529.20 OWF54100.1 - 2.5 8.2 11.0 51 4.0 10.7 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase Phage_Gp23 PF10669.9 OWF54100.1 - 9.1 6.6 6.2 25 5.2 0.2 2.7 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) FliJ PF02050.16 OWF54101.1 - 0.0003 21.0 2.1 0.0003 21.0 2.1 4.9 2 2 2 5 5 5 2 Flagellar FliJ protein Nitroreductase PF00881.24 OWF54101.1 - 0.0052 16.9 0.8 0.013 15.6 0.8 1.7 1 0 0 1 1 1 1 Nitroreductase family DUF5082 PF16888.5 OWF54101.1 - 0.0078 16.5 38.6 0.038 14.3 7.9 4.7 3 2 1 4 4 4 2 Domain of unknown function (DUF5082) XhlA PF10779.9 OWF54101.1 - 0.052 13.8 0.1 0.052 13.8 0.1 5.4 4 2 0 5 5 5 0 Haemolysin XhlA Noelin-1 PF12308.8 OWF54101.1 - 0.086 12.8 0.4 0.086 12.8 0.4 6.0 3 1 3 6 6 6 0 Neurogenesis glycoprotein DUF4618 PF15397.6 OWF54101.1 - 0.27 10.6 46.4 0.69 9.3 4.4 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4618) ADIP PF11559.8 OWF54101.1 - 0.86 9.7 46.6 0.076 13.1 0.8 5.0 4 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 OWF54101.1 - 2.2 8.4 22.7 4.3 7.5 0.0 6.1 5 1 1 6 6 6 0 Basic region leucine zipper Baculo_PEP_C PF04513.12 OWF54101.1 - 3.2 7.8 60.5 0.12 12.5 11.7 5.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2408 PF10303.9 OWF54101.1 - 3.8 8.1 25.1 0.051 14.1 5.3 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2408) COG2 PF06148.11 OWF54102.1 - 0.011 15.9 1.0 0.011 15.9 1.0 4.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1284 PF06935.11 OWF54102.1 - 0.032 14.7 2.3 0.12 12.8 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) NPV_P10 PF05531.12 OWF54102.1 - 0.047 14.2 1.8 0.047 14.2 1.8 4.9 3 3 1 4 4 4 0 Nucleopolyhedrovirus P10 protein PaO PF08417.12 OWF54102.1 - 0.082 13.1 0.0 5.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Pheophorbide a oxygenase MetOD2 PF18548.1 OWF54102.1 - 0.087 12.9 0.2 0.087 12.9 0.2 4.2 4 1 1 5 5 5 0 Metanogen output domain 2 DUF948 PF06103.11 OWF54102.1 - 0.84 9.9 22.9 0.43 10.9 6.5 4.4 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Sec3_C_2 PF15278.6 OWF54102.1 - 1.8 8.9 11.6 0.11 12.8 0.6 3.2 2 1 1 3 3 3 0 Sec3 exocyst complex subunit DUF2203 PF09969.9 OWF54102.1 - 3.4 8.4 16.7 2 9.1 1.2 3.9 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) Cluap1 PF10234.9 OWF54102.1 - 3.5 7.0 27.2 2.2 7.6 10.7 3.0 2 1 1 4 4 4 0 Clusterin-associated protein-1 BLOC1_2 PF10046.9 OWF54102.1 - 3.6 8.0 27.8 11 6.3 3.2 5.7 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LXG PF04740.12 OWF54102.1 - 7.6 6.2 22.7 0.087 12.5 8.2 3.4 3 1 0 3 3 3 0 LXG domain of WXG superfamily Exonuc_VII_L PF02601.15 OWF54102.1 - 8.1 5.9 26.9 1.8e+04 -9.5 26.9 2.3 1 1 0 1 1 0 0 Exonuclease VII, large subunit Linker_histone PF00538.19 OWF54103.1 - 3.6e-22 78.5 0.3 3.6e-22 78.5 0.3 3.0 3 1 0 3 3 3 1 linker histone H1 and H5 family PTPLA PF04387.14 OWF54104.1 - 1.1e-54 184.7 6.1 1.1e-54 184.7 6.1 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.16 OWF54104.1 - 7e-10 39.8 0.0 1.1e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Pkinase PF00069.25 OWF54105.1 - 8.2e-70 235.2 0.1 1.2e-69 234.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 OWF54105.1 - 1.2e-49 166.8 9.1 7e-12 45.8 0.0 5.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF54105.1 - 4.1e-44 148.4 4.8 7.6e-10 39.1 0.1 8.2 1 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF54105.1 - 1.1e-36 124.4 8.4 3.7e-10 39.8 0.1 7.5 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OWF54105.1 - 4.2e-35 121.3 0.0 6.7e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 OWF54105.1 - 3.4e-34 115.8 10.4 3.7e-05 24.0 0.0 10.4 11 0 0 11 11 10 6 Ankyrin repeat Ank_3 PF13606.6 OWF54105.1 - 1.2e-28 95.9 3.9 0.00019 21.6 0.0 9.3 9 0 0 9 9 9 4 Ankyrin repeat Kdo PF06293.14 OWF54105.1 - 2.9e-05 23.5 0.1 7.3e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF54105.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RsgA_GTPase PF03193.16 OWF54105.1 - 0.024 14.5 0.8 0.062 13.2 0.2 2.0 2 0 0 2 2 2 0 RsgA GTPase EcKinase PF02958.20 OWF54105.1 - 0.035 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 OWF54105.1 - 0.036 13.6 0.1 0.036 13.6 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 OWF54105.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF87 PF01935.17 OWF54105.1 - 0.073 13.2 1.5 0.44 10.6 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 OWF54105.1 - 0.4 11.2 3.1 0.71 10.4 0.5 2.3 2 0 0 2 2 2 0 ABC transporter CDT1_C PF16679.5 OWF54106.1 - 0.03 14.8 0.2 0.16 12.4 0.3 2.2 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Ku_PK_bind PF08785.11 OWF54106.1 - 0.1 12.8 0.5 3.2 7.9 0.1 2.7 2 0 0 2 2 2 0 Ku C terminal domain like SRF-TF PF00319.18 OWF54107.1 - 8.9e-25 85.9 0.4 1.3e-24 85.4 0.4 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 OWF54107.1 - 8.5e-06 25.7 0.1 8.5e-06 25.7 0.1 2.5 3 0 0 3 3 3 1 Holliday junction regulator protein family C-terminal repeat DUF4116 PF13475.6 OWF54107.1 - 0.069 12.9 0.4 0.15 11.8 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) GHD PF17834.1 OWF54107.1 - 0.13 12.4 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase DUF3810 PF12725.7 OWF54107.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3668 PF12416.8 OWF54108.1 - 2e-80 269.9 0.0 2e-80 269.9 0.0 2.3 3 0 0 3 3 3 1 Cep120 protein C2 PF00168.30 OWF54108.1 - 4.2e-08 33.4 0.0 0.0019 18.4 0.0 3.3 3 0 0 3 3 3 2 C2 domain DUF4497 PF14924.6 OWF54108.1 - 0.002 18.6 0.0 0.11 12.9 0.0 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) NT-C2 PF10358.9 OWF54108.1 - 0.0052 16.5 0.2 0.025 14.3 0.2 2.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Pkinase PF00069.25 OWF54109.1 - 2.3e-26 92.8 0.0 2.8e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.8 OWF54109.1 - 1.5e-19 70.9 5.5 1.5e-19 70.9 5.5 2.3 2 0 0 2 2 2 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.17 OWF54109.1 - 8.5e-16 58.0 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF54109.1 - 2.7e-08 33.0 0.4 4.1e-08 32.4 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase IMS PF00817.20 OWF54110.1 - 2.3e-39 134.8 0.0 4.3e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OWF54110.1 - 4.1e-16 59.7 0.0 9.9e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 OWF54110.1 - 2.2e-11 44.0 0.0 4.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain REV1_C PF16727.5 OWF54110.1 - 1.5e-10 41.4 0.7 3.2e-10 40.3 0.7 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 OWF54110.1 - 6.1e-10 38.2 18.0 8.6e-05 21.9 0.2 4.4 4 0 0 4 4 4 3 Ubiquitin binding region BRCT PF00533.26 OWF54110.1 - 1e-08 35.4 0.0 2.3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OWF54110.1 - 5.3e-07 29.8 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 OWF54110.1 - 4e-06 26.7 0.1 1.1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 OWF54110.1 - 2.9e-05 24.2 0.0 0.0002 21.5 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif DotD PF16816.5 OWF54110.1 - 0.0067 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 DotD protein DUF1388 PF07142.12 OWF54110.1 - 0.17 11.9 8.5 0.39 10.7 8.5 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) F-box-like PF12937.7 OWF54111.1 - 8.6e-12 44.8 0.1 2e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 OWF54111.1 - 7.5e-09 36.1 0.3 0.00014 22.6 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 OWF54111.1 - 2.6e-06 27.1 0.1 5.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nuc_recep-AF1 PF11825.8 OWF54111.1 - 0.017 15.2 0.2 0.033 14.2 0.2 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 WD40_like PF17005.5 OWF54111.1 - 0.022 14.1 0.0 0.22 10.8 0.1 2.1 2 0 0 2 2 2 0 WD40-like domain Cep57_MT_bd PF06657.13 OWF54111.1 - 0.17 12.4 3.3 1.4 9.5 0.6 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ParA PF10609.9 OWF54112.1 - 6e-87 291.2 0.0 7e-87 290.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OWF54112.1 - 1.3e-13 51.1 0.0 4.5e-12 46.1 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OWF54112.1 - 3.8e-10 40.0 0.3 5.7e-09 36.1 0.3 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 OWF54112.1 - 7.5e-07 28.7 0.1 2e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 OWF54112.1 - 4.7e-06 26.6 0.5 0.081 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 OWF54112.1 - 5.3e-06 25.8 0.3 2.6e-05 23.6 0.4 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 OWF54112.1 - 5.4e-06 26.1 0.2 0.0065 16.0 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 OWF54112.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 OWF54112.1 - 0.0019 17.2 0.2 0.0029 16.6 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 OWF54112.1 - 0.0028 17.6 0.1 0.0059 16.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OWF54112.1 - 0.0037 17.7 0.1 0.0075 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain CBP_BcsQ PF06564.12 OWF54112.1 - 0.0045 16.5 0.1 0.0094 15.5 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 OWF54112.1 - 0.011 15.4 0.1 0.078 12.6 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 OWF54112.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OWF54112.1 - 0.015 15.2 0.8 0.23 11.4 0.2 2.1 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 OWF54112.1 - 0.021 14.7 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 OWF54112.1 - 0.022 14.0 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 OWF54112.1 - 0.023 15.3 0.1 0.041 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 OWF54112.1 - 0.03 13.8 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 OWF54112.1 - 0.04 14.3 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 OWF54112.1 - 0.044 14.1 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 OWF54112.1 - 0.046 13.0 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 OWF54112.1 - 0.052 12.7 0.2 0.099 11.8 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 OWF54112.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 OWF54112.1 - 0.067 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OWF54112.1 - 0.091 13.3 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 OWF54112.1 - 0.1 12.3 0.1 0.27 10.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OWF54112.1 - 0.14 12.2 0.3 0.23 11.5 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 OWF54112.1 - 0.16 12.0 0.1 1.6 8.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OWF54112.1 - 0.19 11.6 0.2 0.32 10.9 0.2 1.3 1 0 0 1 1 1 0 NACHT domain P-mevalo_kinase PF04275.14 OWF54113.1 - 5.4e-46 155.2 0.1 7.7e-46 154.7 0.1 1.2 1 0 0 1 1 1 1 Phosphomevalonate kinase Peptidase_S74 PF13884.6 OWF54113.1 - 0.042 14.2 0.1 0.83 10.0 0.0 2.6 3 0 0 3 3 3 0 Chaperone of endosialidase Neurexophilin PF06312.12 OWF54114.1 - 3e-07 30.1 0.2 5e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 OWF54114.1 - 0.04 14.7 0.0 0.1 13.5 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat P-mevalo_kinase PF04275.14 OWF54115.1 - 1.3e-26 92.8 0.6 1.4e-26 92.7 0.6 1.0 1 0 0 1 1 1 1 Phosphomevalonate kinase Peptidase_S74 PF13884.6 OWF54115.1 - 0.057 13.7 0.2 3.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Chaperone of endosialidase Glyco_hydro_31 PF01055.26 OWF54116.1 - 2.4e-23 83.1 0.0 4e-22 79.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Ank_2 PF12796.7 OWF54118.1 - 9.4e-52 173.5 7.3 3.7e-18 65.9 0.7 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF54118.1 - 4.4e-38 124.9 6.5 0.00028 21.1 0.0 10.6 10 1 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 OWF54118.1 - 7.1e-38 127.4 4.4 2.9e-05 24.3 0.0 8.9 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 OWF54118.1 - 3.5e-36 123.1 2.7 6e-10 39.5 0.2 7.9 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF54118.1 - 6.5e-31 106.0 2.6 2.2e-07 31.0 0.2 7.9 4 1 4 8 8 8 7 Ankyrin repeats (many copies) TPR_12 PF13424.6 OWF54118.1 - 0.0011 19.2 0.0 0.21 11.9 0.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OWF54118.1 - 0.063 13.2 0.2 0.82 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat LapA_dom PF06305.11 OWF54119.1 - 3.9e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain FAM176 PF14851.6 OWF54119.1 - 0.0002 21.0 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 FAM176 family DUF2956 PF11169.8 OWF54119.1 - 0.13 12.5 2.7 0.15 12.3 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) EI24 PF07264.11 OWF54119.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PsbJ PF01788.17 OWF54119.1 - 0.16 11.8 2.8 0.22 11.4 2.8 1.2 1 0 0 1 1 1 0 PsbJ HemY_N PF07219.13 OWF54119.1 - 0.19 12.0 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus PBP1_TM PF14812.6 OWF54119.1 - 0.23 11.9 13.6 0.31 11.4 13.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3169 PF11368.8 OWF54119.1 - 1 8.8 4.7 2.7 7.4 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) EphA2_TM PF14575.6 OWF54119.1 - 9.6 7.2 6.8 55 4.7 6.8 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F5_F8_type_C PF00754.25 OWF54120.1 - 7.3e-06 26.1 0.0 7.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 OWF54120.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) MHC_II_beta PF00969.19 OWF54120.1 - 0.037 14.1 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain DUF167 PF02594.16 OWF54121.1 - 5.5e-25 87.3 0.3 8.6e-25 86.7 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Ig_3 PF13927.6 OWF54122.1 - 4.1e-37 126.6 1.0 6.6e-14 52.3 1.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF54122.1 - 3.2e-36 123.3 0.0 1.6e-12 47.3 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 OWF54122.1 - 2e-28 98.4 0.3 7.9e-10 38.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF54122.1 - 4.7e-27 94.1 0.5 5.7e-12 45.8 0.3 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF54122.1 - 2.5e-21 75.9 2.2 2.3e-08 34.2 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin V-set domain Ig_4 PF16680.5 OWF54122.1 - 5.6e-07 29.7 1.5 0.25 11.6 0.0 4.1 3 2 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 OWF54122.1 - 3.7e-05 23.7 0.0 0.16 12.0 0.1 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 OWF54122.1 - 5.5e-05 23.1 0.1 0.0033 17.4 0.0 2.9 2 1 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 OWF54122.1 - 0.00053 20.3 2.3 0.42 11.0 0.0 4.1 3 2 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 OWF54122.1 - 0.0058 16.2 0.0 0.93 9.1 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF54122.1 - 0.0069 16.4 0.0 4.9 7.3 0.0 2.6 2 0 0 2 2 2 2 C17orf99 Ig domain V-set_CD47 PF08204.11 OWF54122.1 - 0.012 15.6 0.6 1.4 8.9 0.0 3.3 2 1 1 3 3 3 0 CD47 immunoglobulin-like domain I-set PF07679.16 OWF54123.1 - 8.1e-38 128.4 0.0 2.7e-15 56.2 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF54123.1 - 6.5e-36 122.8 1.4 3e-15 56.6 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 OWF54123.1 - 7.5e-25 86.9 0.1 4.9e-09 36.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF54123.1 - 1.2e-20 73.6 0.1 3.4e-12 46.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF54123.1 - 1.5e-18 66.9 0.4 5.6e-06 26.5 0.0 4.7 3 3 1 4 4 4 4 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF54123.1 - 1.9e-05 24.1 0.0 0.15 11.6 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 OWF54123.1 - 2.6e-05 24.2 0.0 0.6 10.2 0.0 3.2 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 OWF54123.1 - 7.2e-05 23.0 0.1 0.043 14.1 0.0 3.3 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 OWF54123.1 - 0.014 15.1 0.0 0.077 12.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 C2-set_2 PF08205.12 OWF54123.1 - 0.016 15.3 2.0 2 8.6 0.0 3.0 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain UL141 PF16758.5 OWF54123.1 - 0.17 11.6 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Herpes-like virus membrane glycoprotein UL141 Ig_3 PF13927.6 OWF54124.1 - 1.6e-34 118.4 0.1 2e-13 50.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF54124.1 - 1.8e-30 104.8 0.1 8.5e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 OWF54124.1 - 6.5e-27 93.5 0.3 9.5e-09 35.3 0.0 3.5 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 OWF54124.1 - 2e-18 66.5 0.1 1.8e-08 34.6 0.0 3.5 2 1 1 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF54124.1 - 1.8e-16 60.3 0.1 4.5e-07 30.0 0.0 4.3 3 1 1 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF54124.1 - 4.2e-07 29.4 0.0 0.1 12.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 OWF54124.1 - 0.0006 19.8 0.1 1.3 9.2 0.0 3.2 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 OWF54124.1 - 0.00081 19.4 0.0 2.9 7.9 0.0 3.1 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain Ig_Tie2_1 PF10430.9 OWF54124.1 - 0.008 16.6 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 Tie-2 Ig-like domain 1 C2-set_2 PF08205.12 OWF54124.1 - 0.028 14.5 0.0 1.4 9.0 0.0 2.9 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain DUF5525 PF17663.1 OWF54124.1 - 0.052 11.6 0.0 0.069 11.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Receptor_2B4 PF11465.8 OWF54124.1 - 0.059 13.6 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Beta-lactamase PF00144.24 OWF54125.1 - 7.5e-85 285.1 3.2 1.9e-43 149.0 0.2 2.2 2 0 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.8 OWF54125.1 - 1.3e-08 35.2 0.3 0.0032 17.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3471) Ig_3 PF13927.6 OWF54126.1 - 1.4e-16 60.8 0.4 8.3e-07 29.5 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 OWF54126.1 - 3.7e-13 49.3 0.0 0.0031 17.6 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF54126.1 - 1.6e-09 38.0 0.4 0.0014 19.0 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 OWF54126.1 - 2.6e-06 27.5 1.4 3.7 7.8 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain Ccdc124 PF06244.12 OWF54127.1 - 3.5e-34 118.2 26.0 1.9e-31 109.3 26.0 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 OWF54127.1 - 0.0025 18.2 0.4 0.0025 18.2 0.4 2.7 2 1 2 4 4 4 1 HMG (high mobility group) box HTH_WhiA PF02650.14 OWF54127.1 - 0.039 14.3 3.4 3.2 8.1 0.1 2.6 2 0 0 2 2 2 0 WhiA C-terminal HTH domain AAA_18 PF13238.6 OWF54130.1 - 8.5e-30 104.0 0.1 1.8e-29 102.9 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 OWF54130.1 - 4.4e-06 27.2 0.0 2e-05 25.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OWF54130.1 - 1.4e-05 25.4 0.1 3.5e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OWF54130.1 - 8.2e-05 23.0 0.0 0.00048 20.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF54130.1 - 0.00013 22.4 0.0 0.00023 21.6 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 OWF54130.1 - 0.0002 21.5 0.1 0.0018 18.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OWF54130.1 - 0.0015 18.9 0.4 0.0069 16.7 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OWF54130.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OWF54130.1 - 0.002 17.5 0.3 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_5 PF07728.14 OWF54130.1 - 0.0046 16.9 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 OWF54130.1 - 0.005 16.8 0.2 0.011 15.6 0.1 1.6 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 OWF54130.1 - 0.0052 16.5 0.1 0.0086 15.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OWF54130.1 - 0.0068 16.8 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Hpr_kinase_C PF07475.12 OWF54130.1 - 0.0086 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain KTI12 PF08433.10 OWF54130.1 - 0.0097 15.4 0.0 0.021 14.3 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 OWF54130.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ADK PF00406.22 OWF54130.1 - 0.019 15.1 0.1 0.3 11.2 0.1 2.2 1 1 0 1 1 1 0 Adenylate kinase IstB_IS21 PF01695.17 OWF54130.1 - 0.02 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 OWF54130.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 OWF54130.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 OWF54130.1 - 0.024 13.9 0.1 0.086 12.1 0.0 1.9 3 0 0 3 3 2 0 Zeta toxin ABC_tran PF00005.27 OWF54130.1 - 0.027 15.0 0.3 0.043 14.3 0.3 1.7 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 OWF54130.1 - 0.027 14.6 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 OWF54130.1 - 0.029 14.3 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 OWF54130.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OWF54130.1 - 0.036 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 OWF54130.1 - 0.037 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 OWF54130.1 - 0.037 12.8 0.1 0.51 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OWF54130.1 - 0.038 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 OWF54130.1 - 0.043 14.2 0.9 0.089 13.1 0.3 1.7 1 1 1 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 OWF54130.1 - 0.053 13.2 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 OWF54130.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain MeaB PF03308.16 OWF54130.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 OWF54130.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 OWF54130.1 - 0.089 12.8 0.0 0.22 11.6 0.0 1.6 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF54130.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 OWF54130.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 OWF54130.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MCM PF00493.23 OWF54130.1 - 0.13 11.3 0.3 0.43 9.6 0.0 1.9 3 0 0 3 3 3 0 MCM P-loop domain AAA_11 PF13086.6 OWF54130.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 OWF54130.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 OWF54130.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 OWF54130.1 - 0.18 11.7 0.0 0.49 10.3 0.0 1.8 2 0 0 2 2 1 0 Adenylylsulphate kinase DUF87 PF01935.17 OWF54130.1 - 0.2 11.7 0.7 2.3 8.3 0.1 2.2 1 1 1 2 2 2 0 Helicase HerA, central domain SKI PF01202.22 OWF54130.1 - 0.21 11.7 1.1 14 5.7 0.0 2.7 2 1 1 3 3 3 0 Shikimate kinase AAA_30 PF13604.6 OWF54130.1 - 0.24 11.1 0.1 0.37 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain PARP PF00644.20 OWF54131.1 - 2.2e-25 89.4 0.2 3.6e-25 88.7 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 OWF54131.1 - 4.1e-21 75.0 0.0 8.1e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 ARTD15 N-terminal domain Exotox-A_cataly PF09009.10 OWF54131.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 1 1 2 2 2 0 Exotoxin A catalytic C1q PF00386.21 OWF54132.1 - 3.9e-20 72.3 0.0 5.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF54132.1 - 0.0025 17.7 0.3 0.0048 16.8 0.3 1.4 1 0 0 1 1 1 1 BclA C-terminal domain HMMR_N PF15905.5 OWF54132.1 - 0.015 14.8 0.3 0.02 14.4 0.3 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 OWF54132.1 - 0.17 12.1 1.2 0.32 11.2 1.2 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Arrestin_N PF00339.29 OWF54133.1 - 1.7e-28 99.6 0.1 2.9e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OWF54133.1 - 5.2e-14 52.9 0.0 2.1e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 OWF54133.1 - 0.098 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like Nuc_sug_transp PF04142.15 OWF54134.1 - 2.5e-37 128.8 22.7 6e-37 127.5 22.6 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OWF54134.1 - 6.9 6.9 26.0 2.9 8.1 3.9 2.4 2 0 0 2 2 2 0 EamA-like transporter family Ribosomal_S17e PF00833.18 OWF54135.1 - 2.9e-65 217.7 0.2 3.3e-65 217.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Translat_reg PF01818.17 OWF54135.1 - 0.033 14.2 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage translational regulator Neur_chan_LBD PF02931.23 OWF54136.1 - 3e-60 203.4 3.8 4.1e-60 202.9 3.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF54136.1 - 4.8e-40 138.1 5.2 1.2e-39 136.9 5.2 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF54137.1 - 9.5e-57 191.9 0.4 1.3e-56 191.4 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF54137.1 - 4.3e-41 141.5 0.2 6e-41 141.1 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4365 PF14280.6 OWF54137.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) NapE PF06796.11 OWF54137.1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.1 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Surfac_D-trimer PF09006.11 OWF54138.1 - 3.2e-07 30.1 10.3 18 5.3 0.0 8.7 6 1 5 12 12 12 1 Lung surfactant protein D coiled-coil trimerisation PAD PF03068.15 OWF54138.1 - 0.00065 18.8 3.8 0.99 8.3 0.2 4.2 1 1 2 4 4 4 2 Protein-arginine deiminase (PAD) Pab87_oct PF13969.6 OWF54138.1 - 0.011 15.8 5.1 39 4.4 0.1 5.6 1 1 7 8 8 8 0 Pab87 octamerisation domain Herpes_TK_C PF08465.10 OWF54138.1 - 0.18 11.5 3.9 30 4.5 0.1 3.4 3 1 0 3 3 3 0 Thymidine kinase from Herpesvirus C-terminal NLPC_P60 PF00877.19 OWF54138.1 - 0.22 11.6 2.3 7.1 6.7 2.3 3.2 1 1 0 1 1 1 0 NlpC/P60 family Syd PF07348.12 OWF54138.1 - 1.7 8.3 9.2 2.3 7.8 0.1 4.3 1 1 3 5 5 5 0 Syd protein (SUKH-2) CX PF01705.19 OWF54138.1 - 2.2 8.9 9.5 58 4.3 0.0 5.6 5 3 3 8 8 8 0 CX module Neur_chan_LBD PF02931.23 OWF54139.1 - 3.5e-59 199.9 0.1 5.4e-59 199.3 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF54139.1 - 6.1e-45 154.1 1.6 7.6e-45 153.8 1.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TIR PF01582.20 OWF54140.1 - 7.5e-15 55.2 0.0 8.2e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF54140.1 - 1.1e-14 55.0 0.0 1.3e-14 54.8 0.0 1.0 1 0 0 1 1 1 1 TIR domain TIR-like PF10137.9 OWF54140.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain ANAPC4_WD40 PF12894.7 OWF54141.1 - 0.00018 21.7 0.0 4.5 7.6 0.0 4.5 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF54141.1 - 0.0002 22.1 2.5 0.16 12.9 0.4 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 OWF54141.1 - 0.00036 20.0 0.0 0.031 13.6 0.0 2.8 3 1 0 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 OWF54141.1 - 0.048 14.2 0.0 1.8 9.2 0.1 3.2 3 0 0 3 3 3 0 PQQ-like domain ubiquitin PF00240.23 OWF54142.1 - 1.7e-16 59.8 0.4 2.9e-16 59.0 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 OWF54142.1 - 6.1e-06 26.1 72.3 0.0019 18.1 8.5 6.5 3 2 4 7 7 7 6 STI1 domain Ubiquitin_5 PF18037.1 OWF54142.1 - 8.2e-06 26.1 0.2 2e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OWF54142.1 - 3.5e-05 23.5 0.3 6.2e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 OWF54142.1 - 4.3e-05 23.3 2.2 7.3e-05 22.6 0.6 2.4 2 0 0 2 2 2 1 UBA/TS-N domain YukD PF08817.10 OWF54142.1 - 0.0062 17.2 0.0 0.028 15.1 0.0 2.2 2 1 0 2 2 1 1 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.9 OWF54142.1 - 0.011 16.3 0.0 0.052 14.1 0.0 2.1 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OWF54142.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like E3_UbLigase_EDD PF11547.8 OWF54142.1 - 0.014 15.1 0.1 0.037 13.7 0.1 1.7 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Ubiquitin_4 PF18036.1 OWF54142.1 - 0.15 12.1 0.6 15 5.7 0.0 2.7 1 1 1 2 2 2 0 Ubiquitin-like domain dCache_1 PF02743.18 OWF54142.1 - 2.3 7.9 6.1 1.7 8.4 1.0 2.5 2 1 0 2 2 2 0 Cache domain Mod_r PF07200.13 OWF54142.1 - 2.8 8.1 10.9 6.1 6.9 0.1 3.2 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3417 PF11897.8 OWF54142.1 - 7.3 7.1 8.7 20 5.7 0.5 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3417) Lustrin_cystein PF14625.6 OWF54143.1 - 8.2e-15 54.9 35.6 3.3e-08 33.7 7.7 3.7 3 2 1 4 4 4 2 Lustrin, cysteine-rich repeated domain Arm PF00514.23 OWF54144.1 - 6.7e-29 99.0 0.2 2.3e-08 33.8 0.0 7.5 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF54144.1 - 1.5e-08 34.9 0.1 6.7e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 OWF54144.1 - 1.3e-06 28.8 0.1 0.072 13.6 0.0 4.9 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 OWF54144.1 - 7.4e-06 25.8 0.5 0.16 12.3 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 OWF54144.1 - 0.0061 15.2 0.0 0.1 11.2 0.0 2.3 2 1 0 2 2 2 1 Adaptin N terminal region Atx10homo_assoc PF09759.9 OWF54144.1 - 0.047 13.7 0.1 2.2 8.4 0.0 3.2 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain A_deamin PF02137.18 OWF54145.1 - 1.6e-102 343.3 0.0 2.5e-102 342.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain z-alpha PF02295.17 OWF54145.1 - 2.8e-10 40.1 0.0 0.0002 21.3 0.1 2.6 2 0 0 2 2 2 2 Adenosine deaminase z-alpha domain dsrm PF00035.26 OWF54145.1 - 2.8e-08 34.3 0.0 1.4e-07 32.1 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif Tim17 PF02466.19 OWF54146.1 - 8.9e-10 38.9 0.1 1.8e-09 38.0 0.1 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Rh5 PF18515.1 OWF54146.1 - 0.19 11.0 0.2 0.23 10.7 0.2 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain DUF4674 PF15719.5 OWF54147.1 - 1.2e-10 41.7 12.8 1.2e-10 41.7 12.8 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4674) zf-ribbon_3 PF13248.6 OWF54147.1 - 0.016 14.6 1.8 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 OWF54147.1 - 0.036 14.1 0.4 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.6 OWF54147.1 - 0.069 13.1 1.5 9.7 6.2 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OWF54147.1 - 0.14 12.3 1.1 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_S27 PF01599.19 OWF54147.1 - 6.5 7.0 6.9 1.4 9.2 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein S27a RRM_1 PF00076.22 OWF54148.1 - 3.2e-17 62.1 0.0 4.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 OWF54148.1 - 6.1e-06 26.1 5.1 1.4e-05 25.0 5.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OWF54148.1 - 0.0023 17.9 1.6 0.0023 17.9 1.6 2.5 2 0 0 2 2 2 1 Zinc knuckle RRM_5 PF13893.6 OWF54148.1 - 0.0042 16.7 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF54148.1 - 0.0075 16.4 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 OWF54149.1 - 7.8e-12 44.9 0.0 1.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 OWF54149.1 - 2.4e-07 30.5 2.5 5.5e-07 29.4 2.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Lig_chan PF00060.26 OWF54150.1 - 4.3e-33 114.3 0.4 7.2e-33 113.5 0.4 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF54150.1 - 1.3e-16 60.8 0.0 2.5e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF54150.1 - 1.4e-15 57.3 0.0 3.3e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 OWF54150.1 - 4.4e-07 29.3 0.0 1.1e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF54150.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF4381 PF14316.6 OWF54150.1 - 0.12 12.7 0.1 0.5 10.6 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4381) SpoIISA_toxin PF14171.6 OWF54150.1 - 3.2 7.4 7.8 0.7 9.5 3.3 2.3 3 0 0 3 3 3 0 Toxin SpoIISA, type II toxin-antitoxin system Colipase-like PF15083.6 OWF54151.1 - 2.7e-07 30.6 29.3 0.0016 18.5 9.3 2.7 1 1 0 2 2 2 2 Colipase-like DUF5496 PF17600.2 OWF54151.1 - 1e-05 25.5 47.2 2.8 8.1 0.4 8.8 1 1 9 10 10 10 9 Family of unknown function (DUF5496) RNase_Zc3h12a PF11977.8 OWF54151.1 - 0.0018 18.1 19.5 1.8e+03 -1.4 19.5 4.2 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Cache_3-Cache_2 PF17201.4 OWF54151.1 - 0.4 9.9 10.5 5.2 6.3 2.3 2.8 1 1 2 3 3 3 0 Cache 3/Cache 2 fusion domain HC2 PF07382.11 OWF54152.1 - 4.1e-21 75.9 187.5 0.41 10.7 18.9 9.8 1 1 4 5 5 5 2 Histone H1-like nucleoprotein HC2 ALIX_LYPXL_bnd PF13949.6 OWF54152.1 - 4.2e-13 49.2 48.5 7.6 5.7 0.1 21.6 1 1 18 19 19 19 11 ALIX V-shaped domain binding to HIV Lig_chan-Glu_bd PF10613.9 OWF54153.1 - 9.4e-33 112.8 0.0 2.5e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 OWF54153.1 - 4.1e-31 107.8 0.3 9.4e-31 106.7 0.3 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OWF54153.1 - 5e-18 65.3 0.0 1.1e-17 64.3 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 OWF54153.1 - 2.9e-16 59.5 0.3 5.6e-16 58.6 0.3 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Aminotran_4 PF01063.19 OWF54154.1 - 9.4e-28 97.6 0.0 1.3e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV DUF2152 PF10222.9 OWF54156.1 - 2.4e-186 620.7 0.5 3e-186 620.4 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Ac76 PF05814.11 OWF54156.1 - 0.3 11.1 2.3 0.8 9.7 0.1 2.5 3 0 0 3 3 3 0 Orf76 (Ac76) OppC_N PF12911.7 OWF54156.1 - 2.4 8.2 4.2 2.1 8.4 1.8 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C BBS2_C PF14782.6 OWF54157.1 - 3.9e-188 625.6 0.6 2.3e-152 507.8 0.0 3.2 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 OWF54157.1 - 2.2e-46 156.3 0.5 3.1e-44 149.4 0.0 3.5 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 OWF54157.1 - 7.9e-40 135.0 0.3 4e-38 129.5 0.2 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 OWF54157.1 - 0.011 14.9 0.6 0.82 8.7 0.1 2.7 1 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 OWF54157.1 - 0.42 11.3 5.6 28 5.4 0.0 4.0 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SH3_1 PF00018.28 OWF54158.1 - 1.4e-11 43.8 0.3 2.7e-11 42.9 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF54158.1 - 1.6e-09 37.5 0.1 4.1e-09 36.2 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OWF54158.1 - 2.3e-06 27.2 0.1 6.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain TMEM247 PF15444.6 OWF54158.1 - 0.11 12.5 3.6 0.26 11.3 3.6 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Glycos_transf_2 PF00535.26 OWF54159.1 - 6.7e-29 100.9 0.0 1.4e-28 99.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 OWF54159.1 - 4.2e-10 39.1 0.0 8.5e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 OWF54159.1 - 4.6e-08 33.2 0.0 7.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OWF54159.1 - 9e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OWF54159.1 - 0.001 18.6 0.0 0.0041 16.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 OWF54159.1 - 0.0018 18.2 0.2 0.0018 18.2 0.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Ricin_B_lectin PF00652.22 OWF54159.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF1359 PF07097.11 OWF54159.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) 7tm_1 PF00001.21 OWF54160.1 - 2.9e-27 95.6 9.2 5.4e-27 94.8 9.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Afaf PF15339.6 OWF54160.1 - 0.076 12.7 0.2 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Acrosome formation-associated factor HOOK PF05622.12 OWF54161.1 - 0.099 10.8 10.9 0.9 7.6 2.9 2.2 1 1 1 2 2 2 0 HOOK protein Ribosomal_L37e PF01907.19 OWF54161.1 - 0.16 12.2 7.3 63 3.8 0.1 4.5 1 1 3 5 5 5 0 Ribosomal protein L37e COX4 PF02936.14 OWF54161.1 - 0.46 10.5 2.5 18 5.4 0.1 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase subunit IV ISAV_HA PF06215.11 OWF54161.1 - 1.3 8.1 3.5 9.4 5.2 0.2 2.7 1 1 2 3 3 3 0 Infectious salmon anaemia virus haemagglutinin Orexin_rec2 PF03827.13 OWF54161.1 - 3.1 7.9 9.2 9.4 6.3 0.2 3.9 2 2 4 6 6 6 0 Orexin receptor type 2 Lectin_C PF00059.21 OWF54162.1 - 5.6e-12 46.4 0.4 2.7e-11 44.2 0.4 2.4 1 0 0 1 1 1 1 Lectin C-type domain PAN_4 PF14295.6 OWF54162.1 - 0.046 13.6 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 PAN domain DUF3599 PF12206.8 OWF54162.1 - 0.082 13.3 2.7 25 5.3 0.0 4.9 3 1 2 5 5 5 0 Domain of unknown function (DUF3599) ComJ PF11033.8 OWF54162.1 - 1.7 8.3 25.6 7.7 6.3 0.3 9.8 10 0 0 10 10 10 0 Competence protein J (ComJ) NP1-WLL PF11733.8 OWF54163.1 - 0.084 12.6 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Tetraspanin PF00335.20 OWF54164.1 - 2.3e-40 138.7 11.0 2.6e-40 138.5 11.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 OWF54165.1 - 8.1e-46 156.6 19.0 9.2e-46 156.4 19.0 1.0 1 0 0 1 1 1 1 Tetraspanin family OTU PF02338.19 OWF54166.1 - 7.1e-10 39.5 0.0 2.2e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 OWF54166.1 - 0.02 14.6 0.0 0.1 12.4 0.0 2.3 1 0 0 1 1 1 0 Ubiquitin family Mut7-C PF01927.16 OWF54166.1 - 0.044 13.9 2.9 3.8 7.6 0.0 3.6 4 0 0 4 4 4 0 Mut7-C RNAse domain IPP-2 PF04979.14 OWF54167.1 - 1.8e-34 119.3 12.7 1.8e-34 119.3 12.7 1.8 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SET PF00856.28 OWF54168.1 - 7e-14 52.6 3.4 1.2e-13 51.8 0.7 2.6 2 1 0 2 2 2 1 SET domain TPR_1 PF00515.28 OWF54168.1 - 6.5e-05 22.6 1.1 0.0023 17.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF54168.1 - 0.00026 20.8 6.6 0.042 14.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF54168.1 - 0.0081 16.3 3.3 3.6 8.0 0.4 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-MYND PF01753.18 OWF54168.1 - 0.011 15.8 18.2 0.011 15.8 18.2 3.4 2 1 0 2 2 2 0 MYND finger TPR_12 PF13424.6 OWF54168.1 - 0.034 14.4 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 OWF54168.1 - 0.034 14.1 0.7 0.097 12.7 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Nif11 PF07862.11 OWF54168.1 - 0.038 14.3 0.0 0.23 11.8 0.0 2.4 3 0 0 3 3 3 0 Nif11 domain RPN1_RPN2_N PF17781.1 OWF54170.1 - 7e-127 423.1 5.2 1.6e-126 421.9 5.2 1.6 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 OWF54170.1 - 2.7e-30 103.3 23.2 1.9e-06 28.0 0.1 9.4 9 0 0 9 9 9 5 Proteasome/cyclosome repeat RPN1_C PF18051.1 OWF54170.1 - 5.6e-20 71.1 0.1 1.1e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 OWF54170.1 - 0.00021 21.6 0.3 0.084 13.3 0.0 3.8 4 0 0 4 4 4 1 HEAT repeats DUF4711 PF15829.5 OWF54170.1 - 0.0082 16.1 0.1 0.0082 16.1 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4711) Zip PF02535.22 OWF54170.1 - 0.064 12.5 0.8 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3438 PF11920.8 OWF54170.1 - 1.4 8.1 7.1 0.55 9.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) SLD3 PF08639.10 OWF54170.1 - 1.5 7.5 12.5 3.6 6.2 0.1 2.2 2 0 0 2 2 2 0 DNA replication regulator SLD3 FAM176 PF14851.6 OWF54170.1 - 7.9 6.1 12.1 0.43 10.2 0.3 2.5 2 0 0 2 2 2 0 FAM176 family Kinesin PF00225.23 OWF54171.1 - 3.8e-116 387.7 0.0 9.2e-116 386.4 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF54171.1 - 1.3e-22 80.4 3.3 1.4e-21 77.0 0.0 2.9 3 0 0 3 3 3 1 Microtubule binding Kinesin_assoc PF16183.5 OWF54171.1 - 0.00067 19.9 6.0 0.022 14.9 0.1 3.4 3 1 0 4 4 4 2 Kinesin-associated DUF745 PF05335.13 OWF54171.1 - 0.0066 16.2 9.3 0.0066 16.2 9.3 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF745) HSP70 PF00012.20 OWF54173.1 - 2e-13 49.4 0.1 5.9e-11 41.3 0.0 2.5 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OWF54173.1 - 1.2e-06 27.7 0.0 0.0004 19.3 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 OWF54173.1 - 0.0062 15.8 0.1 0.48 9.6 0.0 2.3 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 OWF54173.1 - 0.023 14.2 0.0 0.1 12.0 0.0 1.9 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF999 PF06198.11 OWF54173.1 - 0.033 14.2 1.0 0.089 12.8 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF999) BTB_2 PF02214.22 OWF54174.1 - 1.3e-18 67.1 0.0 2.2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF54174.1 - 0.0027 17.9 0.0 0.0045 17.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HCV_NS1 PF01560.17 OWF54174.1 - 0.049 12.3 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 BTB_3 PF16017.5 OWF54174.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Mitofilin PF09731.9 OWF54175.1 - 0.43 9.4 14.9 0.54 9.0 14.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ALMT PF11744.8 OWF54175.1 - 2.1 7.1 9.0 3.5 6.4 9.0 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter RRM_1 PF00076.22 OWF54176.1 - 4.8e-13 48.7 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OWF54177.1 - 1.6e-17 63.0 0.0 2.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF54177.1 - 6e-06 25.9 0.0 9.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF54177.1 - 0.0078 16.3 0.0 0.017 15.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif SET_assoc PF11767.8 OWF54177.1 - 0.16 11.6 0.2 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Arf PF00025.21 OWF54178.1 - 7.8e-75 250.1 0.0 8.6e-75 250.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OWF54178.1 - 1.6e-14 53.8 0.0 1.9e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF54178.1 - 1.9e-14 53.9 0.1 2.5e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OWF54178.1 - 1.3e-11 44.3 0.6 2.8e-07 30.0 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OWF54178.1 - 1.9e-11 43.7 0.0 2.3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF54178.1 - 6.4e-10 38.8 0.0 8.3e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF54178.1 - 0.00013 22.0 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OWF54178.1 - 0.0072 15.6 0.4 0.014 14.7 0.1 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase DUF2754 PF10953.8 OWF54178.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) G-gamma PF00631.22 OWF54179.1 - 2.4e-15 56.3 0.0 2.6e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain LPP PF04728.13 OWF54179.1 - 0.037 14.4 0.6 0.051 14.0 0.6 1.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Met_10 PF02475.16 OWF54180.1 - 2.9e-28 99.0 0.0 5.9e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 OWF54180.1 - 2.5e-05 23.9 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Trm5_N PF18093.1 OWF54180.1 - 0.00019 21.3 0.4 0.00048 20.0 0.4 1.7 1 0 0 1 1 1 1 tRNA methyltransferase 5 N-terminal domain Methyltransf_25 PF13649.6 OWF54180.1 - 0.017 15.8 0.0 0.061 14.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF54180.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Peptidase_C10 PF01640.17 OWF54180.1 - 0.032 14.5 0.5 0.063 13.6 0.4 1.5 1 1 0 1 1 1 0 Peptidase C10 family Methyltransf_18 PF12847.7 OWF54180.1 - 0.037 14.0 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain IFT57 PF10498.9 OWF54180.1 - 0.042 12.8 4.3 0.062 12.3 4.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Kelch_1 PF01344.25 OWF54181.1 - 1.2e-07 31.1 0.5 2.7e-05 23.6 0.4 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 OWF54181.1 - 1.3e-06 28.3 0.0 0.0022 17.9 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 OWF54181.1 - 0.00013 21.9 0.3 0.075 13.1 0.0 3.1 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF54181.1 - 0.0048 17.1 2.7 0.036 14.3 0.2 3.1 2 1 1 3 3 3 1 Kelch motif Kelch_2 PF07646.15 OWF54181.1 - 0.014 15.3 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 0 Kelch motif BTB PF00651.31 OWF54182.1 - 5.2e-26 91.1 0.3 1.2e-25 89.9 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OWF54182.1 - 1.9e-19 69.7 3.2 1.9e-19 69.7 3.2 2.2 3 0 0 3 3 3 1 BTB And C-terminal Kelch CUB PF00431.20 OWF54183.1 - 5.4e-23 81.4 0.3 5e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 CUB domain PRCC PF10253.9 OWF54183.1 - 1.3 9.8 7.2 0.11 13.2 2.4 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Rep_fac-A_C PF08646.10 OWF54184.1 - 6.4e-08 32.5 2.6 2.3e-07 30.6 2.6 2.0 1 0 0 1 1 1 1 Replication factor-A C terminal domain ABC2_membrane PF01061.24 OWF54185.1 - 1.8e-37 128.8 20.7 1.8e-37 128.8 20.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OWF54185.1 - 2.6e-28 99.3 0.0 5e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OWF54185.1 - 6.8e-06 26.1 0.2 1.4e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OWF54185.1 - 0.00036 20.8 0.1 0.00096 19.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OWF54185.1 - 0.0014 18.5 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OWF54185.1 - 0.0047 17.1 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OWF54185.1 - 0.0066 16.8 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OWF54185.1 - 0.0085 15.7 0.6 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OWF54185.1 - 0.015 15.0 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain BTP PF05232.12 OWF54185.1 - 0.017 15.2 0.8 0.05 13.7 0.8 1.8 1 0 0 1 1 1 0 Chlorhexidine efflux transporter Dynamin_N PF00350.23 OWF54185.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 OWF54185.1 - 0.027 14.6 0.5 0.061 13.4 0.5 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 OWF54185.1 - 0.042 14.1 0.2 0.072 13.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OWF54185.1 - 0.045 13.7 0.2 0.12 12.2 0.2 1.8 1 1 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 OWF54185.1 - 0.049 13.2 0.2 0.097 12.3 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 OWF54185.1 - 0.051 13.3 0.3 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 OWF54185.1 - 0.062 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin SMC_N PF02463.19 OWF54185.1 - 0.063 12.7 0.0 1.7 8.0 0.0 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OWF54185.1 - 0.12 13.0 0.4 0.24 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 OWF54185.1 - 0.15 11.8 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OWF54185.1 - 0.28 11.7 3.8 0.18 12.3 0.4 2.2 2 0 0 2 2 2 0 AAA domain NAD_binding_8 PF13450.6 OWF54186.1 - 2.5e-14 53.2 0.3 2.5e-14 53.2 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OWF54186.1 - 1.3e-05 25.0 1.9 1.8e-05 24.5 1.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF54186.1 - 5.6e-05 22.5 0.1 9.2e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OWF54186.1 - 0.00017 21.0 0.0 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OWF54186.1 - 0.00087 18.5 2.8 0.0012 18.0 2.8 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OWF54186.1 - 0.0011 17.8 0.4 0.0017 17.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 OWF54186.1 - 0.003 18.1 1.1 0.0058 17.2 1.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OWF54186.1 - 0.003 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OWF54186.1 - 0.0084 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OWF54186.1 - 0.016 14.6 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OWF54186.1 - 0.016 14.4 0.9 0.025 13.8 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OWF54186.1 - 0.027 13.5 1.6 0.039 13.1 1.6 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF54186.1 - 0.2 10.9 0.8 0.33 10.2 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 OWF54186.1 - 0.34 10.5 0.9 0.54 9.8 0.9 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELO PF01151.18 OWF54187.1 - 9.5e-61 205.5 25.0 1.2e-60 205.2 25.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family HXXEE PF13787.6 OWF54187.1 - 0.19 12.5 0.2 0.19 12.5 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif ELO PF01151.18 OWF54188.1 - 1.2e-63 215.0 25.3 1.5e-63 214.7 25.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Amidase_2 PF01510.25 OWF54189.1 - 6.5e-14 52.5 0.0 1.2e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase 3Beta_HSD PF01073.19 OWF54190.1 - 6.5e-13 48.3 0.0 6.1e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OWF54190.1 - 4.8e-12 45.8 0.0 8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OWF54190.1 - 1.2e-08 35.1 0.0 2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OWF54190.1 - 1.4e-08 34.6 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OWF54190.1 - 7.2e-07 28.6 0.0 3.7e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OWF54190.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OWF54190.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OWF54190.1 - 0.0015 17.8 0.1 0.73 8.9 0.0 3.0 1 1 2 3 3 3 1 Male sterility protein adh_short PF00106.25 OWF54190.1 - 0.0021 17.5 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 OWF54190.1 - 0.0047 17.2 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 OWF54190.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DIM1 PF02966.16 OWF54191.1 - 7.8e-67 223.1 0.4 8.7e-67 222.9 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OWF54191.1 - 1.6e-06 28.1 0.1 2e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OWF54191.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 OWF54191.1 - 0.072 13.4 0.4 0.12 12.7 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredox_DsbH PF03190.15 OWF54191.1 - 0.085 12.8 0.5 0.15 12.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF255 LIX1 PF14954.6 OWF54192.1 - 3.7e-136 452.2 0.1 4.5e-136 452.0 0.1 1.1 1 0 0 1 1 1 1 Limb expression 1 TF_AP-2 PF03299.14 OWF54192.1 - 0.015 15.3 0.1 0.057 13.4 0.0 1.8 2 1 0 2 2 2 0 Transcription factor AP-2 Dicer_dimer PF03368.14 OWF54192.1 - 0.094 12.9 0.2 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Dicer dimerisation domain Sec1 PF00995.23 OWF54193.1 - 8.7e-119 398.3 0.2 1e-118 398.1 0.2 1.0 1 0 0 1 1 1 1 Sec1 family GlutR_dimer PF00745.20 OWF54193.1 - 0.11 13.0 0.0 34 5.0 0.0 2.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF3417 PF11897.8 OWF54193.1 - 0.23 11.9 2.6 16 6.0 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3417) Fibrinogen_C PF00147.18 OWF54194.1 - 2.9e-50 171.1 6.3 3.5e-50 170.9 6.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Pepdidase_M14_N PF18027.1 OWF54194.1 - 0.033 14.5 0.4 0.071 13.5 0.4 1.5 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain tRNA_synt_1c_R2 PF04557.15 OWF54195.1 - 0.083 13.8 1.2 0.18 12.7 0.7 1.8 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 HLH PF00010.26 OWF54196.1 - 0.00017 21.5 0.6 0.00045 20.1 0.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HMG_box PF00505.19 OWF54196.1 - 0.0036 17.7 0.0 0.0093 16.4 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF54196.1 - 0.057 14.0 0.1 0.23 12.1 0.1 2.0 1 0 0 1 1 1 0 HMG-box domain Methyltransf_25 PF13649.6 OWF54197.1 - 4.2e-12 46.6 0.0 8.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF54197.1 - 2.9e-10 40.1 0.2 6.2e-10 39.1 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OWF54197.1 - 8.9e-10 38.4 0.1 1.4e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OWF54197.1 - 1.3e-09 38.6 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF54197.1 - 1.1e-07 31.9 0.0 4.3e-07 29.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 OWF54197.1 - 4.5e-07 29.1 0.0 6.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 OWF54197.1 - 2.8e-05 24.8 0.0 5.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF54197.1 - 3.1e-05 23.4 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OWF54197.1 - 0.00077 19.2 0.1 0.0012 18.7 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OWF54197.1 - 0.0013 18.3 0.2 0.0022 17.6 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OWF54197.1 - 0.0057 16.8 0.0 0.0095 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 OWF54197.1 - 0.014 15.3 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 OWF54197.1 - 0.018 14.4 0.4 0.05 13.0 0.4 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.16 OWF54197.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 OWF54197.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OWF54197.1 - 0.041 13.6 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OWF54197.1 - 0.07 12.7 0.5 0.24 11.0 0.3 1.7 1 1 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Tetraspanin PF00335.20 OWF54198.1 - 8.7e-47 159.8 16.1 9.8e-47 159.6 16.1 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF3867 PF12983.7 OWF54198.1 - 0.051 13.6 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) C1_1 PF00130.22 OWF54199.1 - 0.011 15.6 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 OWF54199.1 - 0.039 14.0 0.8 0.069 13.2 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 OWF54199.1 - 0.14 12.5 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 C1 domain Ras PF00071.22 OWF54200.1 - 7.3e-57 191.5 0.4 8.6e-57 191.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF54200.1 - 3.7e-21 75.5 0.0 5.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF54200.1 - 6.5e-11 42.0 0.1 7.7e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF54200.1 - 1.9e-07 30.8 0.9 8.1e-07 28.8 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF54200.1 - 1.7e-05 24.8 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF54200.1 - 7.1e-05 22.8 1.7 0.14 12.1 0.1 2.5 1 1 1 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OWF54200.1 - 0.00047 19.7 0.7 0.0056 16.2 0.7 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 OWF54200.1 - 0.0011 18.8 1.9 0.012 15.4 0.3 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 OWF54200.1 - 0.0012 18.2 0.2 0.17 11.1 0.2 2.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 OWF54200.1 - 0.0038 16.3 0.2 0.066 12.2 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 OWF54200.1 - 0.015 14.6 0.1 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 Septin CbiA PF01656.23 OWF54200.1 - 0.11 12.5 1.1 0.61 10.1 1.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ldh_1_N PF00056.23 OWF54200.1 - 0.12 12.5 0.1 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain AAA_25 PF13481.6 OWF54200.1 - 0.21 11.1 0.5 0.53 9.8 0.1 1.8 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 OWF54202.1 - 8.2e-43 146.7 27.4 4.4e-39 134.4 11.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF54202.1 - 0.044 12.6 0.1 0.044 12.6 0.1 3.2 2 1 0 3 3 3 0 MFS_1 like family HLH PF00010.26 OWF54205.1 - 7.3e-08 32.2 0.0 1.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1805 PF08827.11 OWF54205.1 - 0.18 12.1 0.1 0.28 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) 7tm_1 PF00001.21 OWF54206.1 - 3.5e-17 62.6 16.3 4.7e-17 62.2 16.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PAC4 PF16093.5 OWF54208.1 - 1.6e-17 63.5 0.0 2.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 CbiG_N PF11760.8 OWF54208.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Polysacc_deac_1 PF01522.21 OWF54209.1 - 1.8e-07 31.1 0.0 7e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 Polysaccharide deacetylase CN_hydrolase PF00795.22 OWF54210.1 - 1.6e-08 34.2 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PPR_2 PF13041.6 OWF54211.1 - 2.7e-08 33.9 0.2 0.00068 19.8 0.1 4.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 OWF54211.1 - 0.00013 21.9 0.7 0.48 10.5 0.1 3.4 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 OWF54211.1 - 0.00053 19.4 0.5 0.026 13.9 0.1 3.3 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OWF54211.1 - 0.01 16.0 17.8 2.2 8.7 0.1 7.2 8 1 0 8 8 8 0 PPR repeat PPR_1 PF12854.7 OWF54211.1 - 1.3 8.8 5.8 3 7.6 0.0 3.8 5 0 0 5 5 5 0 PPR repeat Ig_3 PF13927.6 OWF54213.1 - 2.4e-16 60.1 1.0 8e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 OWF54213.1 - 5.7e-16 58.4 0.0 4.1e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 OWF54213.1 - 1.7e-12 47.3 1.0 7.8e-05 22.8 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF54213.1 - 3.2e-10 40.1 0.9 2e-07 31.1 0.1 3.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF54213.1 - 1.7e-08 34.6 1.5 0.0094 16.3 0.0 3.1 3 1 0 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 OWF54213.1 - 4.2e-05 23.0 1.7 1.9 8.1 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 OWF54213.1 - 0.00016 22.0 0.7 0.36 11.2 0.1 3.7 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 OWF54213.1 - 0.0016 18.6 0.0 11 6.3 0.0 3.6 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 OWF54213.1 - 0.01 15.9 0.4 1.7 8.7 0.0 2.9 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain CH_2 PF06294.11 OWF54214.1 - 1.7e-09 37.7 34.1 5.8 7.1 0.1 12.4 2 1 11 13 13 13 8 CH-like domain in sperm protein UPF0228 PF05727.11 OWF54214.1 - 2.4e-09 37.1 27.2 4.5 7.1 0.2 11.0 1 1 8 9 9 9 6 Uncharacterised protein family (UPF0228) Ofd1_CTDD PF10637.9 OWF54214.1 - 4.5e-08 32.7 8.3 2.5 7.4 0.1 10.1 1 1 3 4 4 4 3 Oxoglutarate and iron-dependent oxygenase degradation C-term SH3_1 PF00018.28 OWF54214.1 - 5.9e-07 29.0 15.4 1.9e+02 1.7 0.0 16.9 5 4 18 23 23 23 0 SH3 domain DUF3642 PF12182.8 OWF54214.1 - 0.00022 21.4 11.2 57 4.1 0.1 7.8 5 3 3 8 8 8 0 Bacterial lipoprotein YqbF PF14553.6 OWF54214.1 - 0.00036 20.3 52.2 16 5.5 0.1 15.9 1 1 21 23 23 23 3 YqbF, hypothetical protein domain Med18 PF09637.10 OWF54214.1 - 0.0074 16.2 56.2 1.5 8.6 0.7 11.1 1 1 10 11 11 11 4 Med18 protein Aldo_ket_red PF00248.21 OWF54214.1 - 0.041 13.1 22.4 2.5 7.2 0.3 6.0 1 1 2 3 3 3 0 Aldo/keto reductase family Ig_3 PF13927.6 OWF54215.1 - 4.8e-16 59.1 0.0 1.4e-06 28.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 OWF54215.1 - 1.2e-14 54.1 0.0 8.2e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 OWF54215.1 - 2.5e-13 50.0 0.5 3.1e-06 27.2 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 OWF54215.1 - 2.4e-11 43.8 0.0 0.00034 20.9 0.0 3.0 2 2 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF54215.1 - 3.6e-05 23.9 2.7 0.00065 19.8 0.0 3.4 3 2 0 3 3 3 1 Immunoglobulin V-set domain C1-set PF07654.15 OWF54215.1 - 0.0015 18.9 0.0 0.56 10.6 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 OWF54215.1 - 0.058 13.5 1.6 11 6.1 0.1 3.5 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain TNFR_c6 PF00020.18 OWF54216.1 - 0.0035 17.7 6.1 0.0035 17.7 6.1 3.3 3 0 0 3 3 3 1 TNFR/NGFR cysteine-rich region OstA PF03968.14 OWF54217.1 - 2.3e-17 63.2 0.0 4.1 7.6 0.0 16.7 1 1 2 3 3 3 3 OstA-like protein DUF4573 PF15140.6 OWF54218.1 - 0.078 12.8 3.1 0.097 12.5 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) ChW PF07538.11 OWF54219.1 - 0.24 11.4 1.2 16 5.5 0.1 2.4 2 0 0 2 2 2 0 Clostridial hydrophobic W Mucin PF01456.17 OWF54219.1 - 0.83 9.6 16.3 0.84 9.6 16.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.22 OWF54221.1 - 7.6e-90 301.9 1.3 9.4e-90 301.6 1.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Speriolin_C PF15059.6 OWF54221.1 - 0.037 14.2 0.1 0.09 12.9 0.1 1.6 1 0 0 1 1 1 0 Speriolin C-terminus DUF899 PF05988.12 OWF54223.1 - 0.029 13.9 4.2 14 5.1 0.1 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF899) zf-C2H2_9 PF16293.5 OWF54223.1 - 0.059 13.2 5.4 22 5.0 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-NADH-PPase PF09297.11 OWF54223.1 - 2.4 7.9 15.8 12 5.6 1.0 3.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain LSM PF01423.22 OWF54224.1 - 6.4e-20 70.6 0.0 8.3e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sushi PF00084.20 OWF54225.1 - 0.00033 21.2 0.1 0.00077 20.0 0.1 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) TMEM154 PF15102.6 OWF54225.1 - 0.00071 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family SIT PF15330.6 OWF54225.1 - 0.0054 17.2 0.1 0.016 15.6 0.0 1.8 1 1 1 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 OWF54225.1 - 0.0086 16.9 0.1 0.026 15.4 0.1 2.1 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OWF54225.1 - 0.021 14.7 0.3 0.05 13.5 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain Chordopox_A13L PF05961.11 OWF54225.1 - 0.027 14.7 0.1 0.096 12.9 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Consortin_C PF15281.6 OWF54225.1 - 0.08 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Consortin C-terminus GRP PF07172.11 OWF54225.1 - 0.094 13.4 0.4 0.69 10.6 0.0 2.1 1 1 1 2 2 2 0 Glycine rich protein family Herpes_gE PF02480.16 OWF54225.1 - 0.1 11.4 0.2 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E ECSCR PF15820.5 OWF54225.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 OWF54225.1 - 0.13 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF2615 PF11027.8 OWF54225.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF2207 PF09972.9 OWF54225.1 - 0.15 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RCR PF12273.8 OWF54225.1 - 2.9 8.6 7.6 6.6 7.4 7.6 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Zona_pellucida PF00100.23 OWF54227.1 - 2.1e-33 116.2 11.8 2.1e-33 116.2 11.8 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain CUB PF00431.20 OWF54227.1 - 6.9e-16 58.6 0.6 2.6e-15 56.7 0.0 2.3 3 0 0 3 3 3 1 CUB domain CUB_2 PF02408.20 OWF54227.1 - 0.031 14.0 0.1 0.15 11.9 0.1 2.3 1 0 0 1 1 1 0 CUB-like domain CMAS PF02353.20 OWF54228.1 - 9.7e-39 133.3 0.3 1.3e-38 132.9 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OWF54228.1 - 2.8e-11 43.5 0.0 4.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF54228.1 - 7e-11 42.7 0.0 1.6e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF54228.1 - 8.3e-10 39.2 0.0 1.7e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF54228.1 - 2e-09 38.1 0.0 3.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF54228.1 - 1e-07 31.7 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OWF54228.1 - 2.7e-07 30.5 0.0 5.2e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OWF54228.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 OWF54228.1 - 0.02 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OWF54228.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_16 PF10294.9 OWF54228.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 OWF54228.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 OWF54228.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Zona_pellucida PF00100.23 OWF54229.1 - 1.1e-30 107.4 10.0 1.1e-30 107.4 10.0 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain SRCR PF00530.18 OWF54229.1 - 3e-15 56.5 0.2 8.8e-15 55.0 0.2 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF54229.1 - 0.0095 16.5 1.0 0.0095 16.5 1.0 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Peptidase_M14 PF00246.24 OWF54230.1 - 2.3e-81 273.8 0.0 2.8e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OWF54230.1 - 2.3e-18 66.3 0.0 4.2e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide B12D PF06522.11 OWF54231.1 - 0.00093 18.9 0.1 0.0021 17.8 0.0 1.6 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MPP6 PF10175.9 OWF54231.1 - 0.0095 16.4 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 7tm_1 PF00001.21 OWF54233.1 - 7.1e-17 61.6 26.3 9.2e-17 61.2 26.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF54233.1 - 1.8e-10 40.7 34.3 7.9e-10 38.5 34.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF54233.1 - 0.022 14.4 32.8 0.014 15.1 29.9 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PMP22_Claudin PF00822.20 OWF54234.1 - 3.6e-22 79.0 3.0 5.9e-22 78.3 3.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF54234.1 - 8.2e-20 71.4 0.7 1.3e-19 70.8 0.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 OWF54234.1 - 0.0013 19.0 2.3 0.0021 18.3 2.3 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein NCE101 PF11654.8 OWF54234.1 - 0.022 14.5 0.9 0.053 13.2 0.0 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 DUF973 PF06157.11 OWF54234.1 - 0.11 11.5 1.6 0.15 11.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4199 PF13858.6 OWF54234.1 - 0.17 12.3 2.9 0.39 11.1 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3899 PF13038.6 OWF54234.1 - 0.34 11.4 11.0 1 9.9 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) Amastin PF07344.11 OWF54234.1 - 0.59 10.0 8.1 0.1 12.4 1.1 2.4 1 1 1 2 2 2 0 Amastin surface glycoprotein CD20 PF04103.15 OWF54234.1 - 0.97 9.5 10.1 12 5.9 0.0 3.3 3 0 0 3 3 3 0 CD20-like family Phage_holin_3_6 PF07332.11 OWF54234.1 - 1.7 8.7 3.3 15 5.6 1.4 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III 7tm_1 PF00001.21 OWF54235.1 - 4.7e-22 78.6 11.8 6e-22 78.2 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 OWF54235.1 - 0.03 13.3 0.0 0.03 13.3 0.0 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin RAP1 PF07218.11 OWF54235.1 - 0.12 10.6 2.0 0.19 10.0 0.9 1.7 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) 7tm_1 PF00001.21 OWF54236.1 - 9.6e-17 61.2 13.6 1.3e-16 60.8 13.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 OWF54236.1 - 0.021 13.8 0.1 0.021 13.8 0.1 2.3 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin OAD_gamma PF04277.13 OWF54236.1 - 0.34 11.5 3.8 19 5.9 1.4 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Arch_flagellin PF01917.16 OWF54236.1 - 0.61 10.3 2.0 1 9.5 2.0 1.3 1 0 0 1 1 1 0 Archaebacterial flagellin 7tm_1 PF00001.21 OWF54237.1 - 3.4e-17 62.7 10.3 4.2e-17 62.3 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 OWF54237.1 - 0.018 14.0 0.0 0.018 14.0 0.0 2.2 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Gemini_mov PF01708.16 OWF54237.1 - 0.16 11.8 0.8 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein TMEM154 PF15102.6 OWF54237.1 - 0.4 10.6 2.8 1.2 9.1 0.0 2.6 3 0 0 3 3 3 0 TMEM154 protein family EphA2_TM PF14575.6 OWF54237.1 - 1.1 10.2 0.1 1.1 10.2 0.1 3.4 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain 7tm_1 PF00001.21 OWF54238.1 - 3.4e-21 75.8 9.9 4.4e-21 75.4 9.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 OWF54238.1 - 0.0073 15.3 0.0 0.0073 15.3 0.0 2.2 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin Frag1 PF10277.9 OWF54238.1 - 0.025 14.1 12.1 0.41 10.1 8.4 2.9 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family MFS_1 PF07690.16 OWF54239.1 - 0.00019 20.5 2.2 0.00019 20.5 2.2 2.6 1 1 1 3 3 3 3 Major Facilitator Superfamily WD40 PF00400.32 OWF54240.1 - 9.8e-15 54.7 16.4 0.00083 20.1 0.1 8.1 7 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF54240.1 - 3.1e-11 43.4 0.1 0.039 14.2 0.0 4.5 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF54240.1 - 0.02 14.2 0.5 2.1 7.6 0.0 2.2 1 1 0 2 2 2 0 WD40-like domain DAO_C PF16901.5 OWF54240.1 - 0.048 13.5 0.1 1 9.3 0.2 2.3 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase DUF4315 PF14193.6 OWF54240.1 - 0.56 10.3 2.5 1.2 9.2 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Mst1_SARAH PF11629.8 OWF54241.1 - 0.51 10.5 4.4 3.2 7.9 2.6 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 MBD PF01429.19 OWF54242.1 - 5.5e-17 61.2 0.0 1.6e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain HhH-GPD PF00730.25 OWF54242.1 - 0.00014 22.2 0.0 0.00035 21.0 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Clr2_transil PF16761.5 OWF54242.1 - 0.15 12.9 0.0 0.48 11.3 0.0 1.8 1 0 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 LSM PF01423.22 OWF54244.1 - 2.7e-19 68.6 0.3 3.5e-19 68.3 0.3 1.2 1 0 0 1 1 1 1 LSM domain vATP-synt_E PF01991.18 OWF54244.1 - 0.035 13.5 0.1 0.035 13.5 0.1 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF150_C PF17384.2 OWF54244.1 - 0.039 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain CytochromB561_N PF09786.9 OWF54245.1 - 6.7e-57 193.8 6.7 1.6e-55 189.2 3.7 2.8 1 1 1 2 2 2 2 Cytochrome B561, N terminal zf-RING_UBOX PF13445.6 OWF54246.1 - 1.3e-10 41.1 5.4 1.3e-10 41.1 5.4 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF54246.1 - 4e-08 33.0 3.8 4e-08 33.0 3.8 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF54246.1 - 6.4e-08 32.6 5.9 6.4e-08 32.6 5.9 3.4 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF54246.1 - 7.2e-07 28.9 2.6 7.2e-07 28.9 2.6 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF54246.1 - 6.4e-06 26.4 3.4 6.4e-06 26.4 3.4 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OWF54246.1 - 2.1e-05 24.4 2.3 2.1e-05 24.4 2.3 3.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF54246.1 - 6.9e-05 22.6 2.0 6.9e-05 22.6 2.0 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 OWF54246.1 - 0.00011 22.3 5.5 0.00011 22.3 5.5 3.6 3 1 0 3 3 3 2 B-box zinc finger C1_4 PF07975.12 OWF54246.1 - 0.0039 17.4 5.9 0.0039 17.4 5.9 4.1 4 0 0 4 4 4 1 TFIIH C1-like domain zf-Nse PF11789.8 OWF54246.1 - 0.005 16.6 0.5 0.016 15.0 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit AAA_15 PF13175.6 OWF54246.1 - 0.012 15.4 4.3 0.015 15.0 4.3 1.1 1 0 0 1 1 1 0 AAA ATPase domain PhaC_N PF07167.13 OWF54246.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Pro_CA PF00484.19 OWF54246.1 - 0.022 15.1 0.5 0.045 14.0 0.5 1.7 1 0 0 1 1 1 0 Carbonic anhydrase zf-RING_11 PF17123.5 OWF54246.1 - 0.16 11.8 4.8 0.83 9.4 4.8 2.4 1 0 0 1 1 1 0 RING-like zinc finger BORCS7 PF16088.5 OWF54246.1 - 0.24 11.7 3.8 0.42 10.9 0.6 2.5 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Syntaxin_2 PF14523.6 OWF54246.1 - 1.4 9.3 7.5 2.1 8.8 5.3 2.3 2 0 0 2 2 2 0 Syntaxin-like protein zf-RING_UBOX PF13445.6 OWF54247.1 - 1.1e-09 38.2 7.1 1.1e-09 38.2 7.1 3.3 4 0 0 4 4 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF54247.1 - 2.8e-08 33.5 6.7 2.8e-08 33.5 6.7 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF54247.1 - 5.7e-08 32.8 9.1 5.7e-08 32.8 9.1 3.1 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF54247.1 - 3.4e-07 30.5 6.0 3.4e-07 30.5 6.0 3.7 4 0 0 4 4 2 1 Ring finger domain zf-RING_5 PF14634.6 OWF54247.1 - 1.1e-06 28.5 5.5 1.1e-06 28.5 5.5 3.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF54247.1 - 3.9e-06 26.6 4.9 3.9e-06 26.6 4.9 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) SBBP PF06739.11 OWF54247.1 - 2.7e-05 24.1 0.3 2.7e-05 24.1 0.3 2.0 2 0 0 2 2 2 1 Beta-propeller repeat NHL PF01436.21 OWF54247.1 - 8.2e-05 22.5 0.6 0.11 12.6 0.0 3.8 4 0 0 4 4 3 1 NHL repeat zf-B_box PF00643.24 OWF54247.1 - 8.9e-05 22.6 5.4 8.9e-05 22.6 5.4 3.8 4 0 0 4 4 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 OWF54247.1 - 0.00011 22.0 9.1 0.00011 22.0 9.1 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) C1_4 PF07975.12 OWF54247.1 - 0.0049 17.1 4.2 0.0049 17.1 4.2 4.2 4 1 1 5 5 5 1 TFIIH C1-like domain Prok-RING_4 PF14447.6 OWF54247.1 - 0.014 15.3 6.7 0.014 15.3 6.7 3.3 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OWF54247.1 - 0.025 14.4 2.9 0.072 12.9 2.9 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PhaC_N PF07167.13 OWF54247.1 - 0.026 14.2 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Pro_CA PF00484.19 OWF54247.1 - 0.044 14.1 0.2 0.094 13.0 0.2 1.6 1 0 0 1 1 1 0 Carbonic anhydrase BORCS7 PF16088.5 OWF54247.1 - 0.071 13.4 4.2 0.13 12.6 0.6 2.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 zf-RING_11 PF17123.5 OWF54247.1 - 0.15 11.8 4.4 0.85 9.4 4.4 2.5 1 0 0 1 1 1 0 RING-like zinc finger PBECR5 PF18814.1 OWF54247.1 - 0.57 10.1 5.1 0.29 11.0 2.8 1.7 2 0 0 2 2 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 zf-HC2 PF13490.6 OWF54247.1 - 0.99 9.7 4.8 2.9 8.2 0.1 3.0 3 0 0 3 3 2 0 Putative zinc-finger Syntaxin_2 PF14523.6 OWF54247.1 - 1 9.8 10.0 1.9 8.9 5.3 2.6 1 1 1 2 2 2 0 Syntaxin-like protein zf-RING_UBOX PF13445.6 OWF54248.1 - 1.3e-09 37.9 7.8 1.3e-09 37.9 7.8 3.1 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF54248.1 - 2.9e-08 33.4 6.7 2.9e-08 33.4 6.7 3.6 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF54248.1 - 5.4e-08 32.9 9.3 5.4e-08 32.9 9.3 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF54248.1 - 2.6e-07 30.8 6.2 2.6e-07 30.8 6.2 3.9 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF54248.1 - 1.1e-06 28.4 4.9 1.1e-06 28.4 4.9 3.1 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54248.1 - 1.8e-06 27.8 5.5 1.8e-06 27.8 5.5 3.3 3 1 0 3 3 2 1 zinc-RING finger domain zf-B_box PF00643.24 OWF54248.1 - 9.2e-05 22.5 5.4 9.2e-05 22.5 5.4 3.8 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.6 OWF54248.1 - 0.00011 21.9 9.5 0.00011 21.9 9.5 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Focal_AT PF03623.13 OWF54248.1 - 0.00072 19.5 1.0 0.0019 18.2 1.0 1.7 1 0 0 1 1 1 1 Focal adhesion targeting region Pro_CA PF00484.19 OWF54248.1 - 0.023 15.0 0.3 0.066 13.5 0.1 2.0 2 0 0 2 2 2 0 Carbonic anhydrase zf-Nse PF11789.8 OWF54248.1 - 0.08 12.8 7.7 0.034 14.0 3.1 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OWF54248.1 - 0.11 12.4 14.8 0.036 13.9 8.4 3.4 3 1 0 3 3 2 0 Prokaryotic RING finger family 4 Syntaxin_2 PF14523.6 OWF54248.1 - 0.13 12.7 9.1 0.13 12.7 6.1 2.3 1 1 1 2 2 2 0 Syntaxin-like protein NHL PF01436.21 OWF54248.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 NHL repeat PBECR5 PF18814.1 OWF54248.1 - 0.38 10.7 5.7 0.34 10.8 3.9 1.7 2 1 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 DUF3450 PF11932.8 OWF54248.1 - 0.7 9.2 5.6 1.4 8.1 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 OWF54248.1 - 5.4 7.0 10.8 3.6 7.6 7.2 2.6 2 1 1 3 3 3 0 Prefoldin subunit Podoplanin PF05808.11 OWF54249.1 - 0.0014 18.7 2.2 0.0023 18.0 2.2 1.3 1 0 0 1 1 1 1 Podoplanin CIMR PF00878.18 OWF54250.1 - 2e-07 31.2 3.6 0.0073 16.4 0.4 3.7 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Ephrin_rec_like PF07699.13 OWF54250.1 - 1.7e-06 27.6 55.2 0.0014 18.3 4.9 7.6 4 3 3 7 7 7 6 Putative ephrin-receptor like DUF3695 PF12494.8 OWF54251.1 - 2.3e-32 110.8 0.2 3.2e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) ANF_receptor PF01094.28 OWF54252.1 - 1.3e-93 314.0 0.2 1.3e-93 314.0 0.2 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region 7tm_3 PF00003.22 OWF54252.1 - 2.3e-66 223.9 25.6 2.3e-66 223.9 25.6 1.7 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 OWF54252.1 - 1.7e-11 43.9 12.8 4.1e-11 42.7 12.8 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 OWF54252.1 - 0.049 14.0 0.1 0.16 12.3 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5438) M-factor PF03855.13 OWF54253.1 - 0.00058 20.0 6.6 0.0085 16.2 1.1 2.9 1 1 2 3 3 3 3 M-factor SCAB-Ig PF16709.5 OWF54253.1 - 0.017 15.2 0.3 38 4.4 0.0 3.6 1 1 3 4 4 4 0 Ig domain of plant-specific actin-binding protein DUF746 PF05344.11 OWF54254.1 - 0.0071 16.2 0.2 25 4.8 0.0 4.1 1 1 4 6 6 6 1 Domain of Unknown Function (DUF746) UCR_hinge PF02320.16 OWF54254.1 - 0.053 13.7 0.2 29 5.0 0.0 3.3 3 2 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein Vault PF01505.18 OWF54254.1 - 0.3 11.3 2.9 1.2e+02 3.0 0.0 3.8 4 0 0 4 4 4 0 Major Vault Protein repeat domain Prok-E2_E PF14462.6 OWF54254.1 - 4.7 7.1 5.0 43 3.9 0.0 4.0 2 1 3 5 5 5 0 Prokaryotic E2 family E M-factor PF03855.13 OWF54255.1 - 0.0017 18.5 22.7 0.13 12.4 0.5 4.7 2 2 3 5 5 5 3 M-factor Reo_sigmaC PF04582.12 OWF54255.1 - 0.04 14.2 1.1 19 5.5 0.1 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein C-terminal domain S_4TM PF18159.1 OWF54255.1 - 0.078 12.3 0.0 2.9 7.1 0.0 2.2 1 1 0 2 2 2 0 SMODS-associating 4TM effector domain XendoU PF09412.10 OWF54255.1 - 0.36 10.0 1.6 17 4.5 0.3 3.3 1 1 3 4 4 4 0 Endoribonuclease XendoU MAM PF00629.23 OWF54256.1 - 1e-166 548.8 46.1 2.6e-27 95.7 0.0 16.3 16 1 0 16 16 15 13 MAM domain, meprin/A5/mu Ig_3 PF13927.6 OWF54256.1 - 3.5e-65 216.6 43.9 4.6e-10 40.0 0.3 8.7 8 0 0 8 8 7 7 Immunoglobulin domain I-set PF07679.16 OWF54256.1 - 1.2e-62 208.0 3.7 4.3e-07 29.9 0.0 7.8 7 0 0 7 7 7 7 Immunoglobulin I-set domain CUB PF00431.20 OWF54256.1 - 2.8e-59 198.2 0.2 1.8e-19 70.1 0.0 4.3 4 0 0 4 4 3 3 CUB domain Trypsin PF00089.26 OWF54256.1 - 7.2e-40 137.1 0.0 7.2e-40 137.1 0.0 2.4 2 0 0 2 2 1 1 Trypsin SRCR PF00530.18 OWF54256.1 - 1.3e-37 128.3 17.7 2.7e-19 69.5 1.1 5.3 4 0 0 4 4 4 2 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 OWF54256.1 - 3.3e-36 123.2 141.1 7.6e-08 32.4 6.7 11.1 11 1 0 11 11 10 8 Low-density lipoprotein receptor domain class A ig PF00047.25 OWF54256.1 - 2.5e-34 117.3 25.9 0.00023 21.2 0.0 8.6 8 1 0 8 8 7 7 Immunoglobulin domain V-set PF07686.17 OWF54256.1 - 2.5e-33 114.5 19.5 0.00089 19.4 0.0 12.8 7 7 0 7 7 7 7 Immunoglobulin V-set domain Ig_2 PF13895.6 OWF54256.1 - 9.4e-28 96.4 24.7 7e-05 23.1 0.1 8.7 8 0 0 8 8 7 7 Immunoglobulin domain SEA PF01390.20 OWF54256.1 - 1.7e-08 34.5 6.6 2.6e-07 30.7 2.2 3.3 3 0 0 3 3 2 1 SEA domain SRCR_2 PF15494.6 OWF54256.1 - 5.4e-06 26.9 9.0 0.0028 18.2 0.6 4.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain EGF PF00008.27 OWF54256.1 - 2.5e-05 24.5 6.1 2.5e-05 24.5 6.1 6.4 6 0 0 6 6 5 1 EGF-like domain Ig_C17orf99 PF17736.1 OWF54256.1 - 7.2e-05 22.7 3.7 12 6.0 0.0 7.3 8 0 0 8 8 8 0 C17orf99 Ig domain CBM64 PF18666.1 OWF54256.1 - 0.23 11.6 9.1 16 5.7 0.0 6.4 7 0 0 7 7 6 0 Carbohydrate-binding module 64 CXCR4_N PF12109.8 OWF54256.1 - 4.3 7.6 22.8 30 4.9 0.1 6.4 6 0 0 6 6 5 0 CXCR4 Chemokine receptor N terminal BAMBI PF06211.12 OWF54257.1 - 0.0088 16.3 0.4 0.0088 16.3 0.4 2.2 1 1 1 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain IATP PF04568.12 OWF54258.1 - 3.3e-25 88.4 5.1 4e-25 88.1 5.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP ABC_tran_Xtn PF12848.7 OWF54258.1 - 0.15 12.1 5.8 0.23 11.5 5.7 1.4 1 1 0 1 1 1 0 ABC transporter MFS_1 PF07690.16 OWF54259.1 - 1e-50 172.6 46.5 3.7e-33 114.9 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF54259.1 - 8.2e-10 38.1 1.6 8.2e-10 38.1 1.6 3.6 2 2 0 2 2 2 1 MFS_1 like family zf-H2C2_2 PF13465.6 OWF54260.1 - 2.1e-12 46.9 24.2 2.2e-06 27.8 4.5 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 OWF54260.1 - 5.6e-11 42.3 21.3 0.00029 21.1 6.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF54260.1 - 5.4e-08 33.0 25.2 0.0011 19.6 5.0 4.1 5 0 0 5 5 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF54260.1 - 1.5e-05 25.1 10.1 0.027 14.8 0.2 4.0 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF54260.1 - 0.0014 18.6 18.6 0.83 9.7 3.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF54260.1 - 0.02 14.7 2.3 0.02 14.7 2.3 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF2256 PF10013.9 OWF54260.1 - 0.033 14.3 8.3 4 7.6 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 OWF54260.1 - 0.037 13.8 1.9 0.037 13.8 1.9 2.9 2 1 0 3 3 3 0 GAGA factor zf-met PF12874.7 OWF54260.1 - 0.062 13.7 16.1 0.57 10.6 2.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type C1_4 PF07975.12 OWF54260.1 - 0.11 12.7 0.6 0.11 12.7 0.6 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3268 PF11672.8 OWF54260.1 - 0.13 12.6 2.5 0.25 11.7 1.6 2.0 2 1 0 2 2 1 0 zinc-finger-containing domain zf-C2HC_2 PF13913.6 OWF54260.1 - 0.21 11.5 12.3 0.25 11.3 0.5 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-trcl PF13451.6 OWF54260.1 - 0.48 10.4 10.2 0.26 11.2 4.1 2.9 2 1 0 2 2 2 0 Probable zinc-ribbon domain FYVE PF01363.21 OWF54260.1 - 1.6 8.9 12.3 4.9 7.4 12.1 1.9 1 1 0 1 1 1 0 FYVE zinc finger BolA PF01722.18 OWF54260.1 - 1.8 8.9 5.0 5.6 7.3 0.3 2.7 3 0 0 3 3 2 0 BolA-like protein Prok-RING_1 PF14446.6 OWF54260.1 - 2.8 7.9 8.2 19 5.3 0.3 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_3rep PF18868.1 OWF54260.1 - 3 8.6 9.9 8.7 7.0 6.5 2.9 2 1 0 2 2 1 0 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 OWF54260.1 - 7.3 6.8 10.7 4.7 7.4 1.9 2.5 1 1 1 2 2 2 0 KIAA1045 RING finger LRR_8 PF13855.6 OWF54261.1 - 2e-69 229.2 54.2 1.4e-08 34.3 1.4 12.7 6 4 6 14 14 14 13 Leucine rich repeat LRR_4 PF12799.7 OWF54261.1 - 2.8e-61 202.4 65.8 5.4e-06 26.7 0.1 16.5 10 5 7 18 18 18 16 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF54261.1 - 3.1e-17 60.5 55.5 11 7.0 0.1 21.6 22 2 1 23 23 23 5 Leucine Rich Repeat LRR_6 PF13516.6 OWF54261.1 - 1.2e-13 49.9 58.8 0.85 9.8 0.0 19.2 21 0 0 21 21 21 5 Leucine Rich repeat LRR_9 PF14580.6 OWF54261.1 - 2.5e-10 40.1 37.5 0.058 12.9 0.8 7.3 1 1 8 9 9 9 9 Leucine-rich repeat RsmF_methylt_CI PF17126.5 OWF54261.1 - 0.0042 17.1 5.8 67 3.6 0.0 8.0 9 3 2 11 11 11 0 RsmF rRNA methyltransferase first C-terminal domain DUF2322 PF10084.9 OWF54261.1 - 0.017 15.2 0.4 20 5.3 0.0 3.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) SAM_2 PF07647.17 OWF54262.1 - 1.6e-06 28.1 16.7 12 6.1 0.2 8.2 1 1 9 10 10 10 3 SAM domain (Sterile alpha motif) DnaA_N PF11638.8 OWF54262.1 - 0.00011 21.8 20.1 5.9 6.7 0.3 6.4 1 1 4 5 5 5 4 DnaA N-terminal domain CoiA PF06054.11 OWF54262.1 - 0.0003 20.1 26.4 0.069 12.3 5.9 3.1 1 1 3 4 4 4 4 Competence protein CoiA-like family Lip_prot_lig_C PF10437.9 OWF54262.1 - 0.00087 19.2 16.4 7.6 6.6 0.3 6.3 1 1 4 5 5 5 2 Bacterial lipoate protein ligase C-terminus DUF3181 PF11378.8 OWF54262.1 - 0.012 15.9 34.4 1.8e+04 -19.0 34.4 5.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3181) DUF4093 PF13331.6 OWF54262.1 - 0.013 16.0 31.2 43 4.6 0.9 8.4 1 1 8 9 9 9 0 Domain of unknown function (DUF4093) Med31 PF05669.12 OWF54262.1 - 0.13 12.3 48.6 3.5 7.7 13.0 4.3 1 1 3 4 4 4 0 SOH1 PhoPQ_related PF10142.9 OWF54262.1 - 0.38 9.4 30.1 0.83 8.2 9.7 2.9 1 1 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein MannoseP_isomer PF01050.18 OWF54262.1 - 0.48 10.3 29.0 3.2 7.6 1.5 4.9 1 1 4 5 5 5 0 Mannose-6-phosphate isomerase Transket_pyr PF02779.24 OWF54262.1 - 4.9 6.8 7.4 0.92 9.2 1.9 2.3 1 1 1 2 2 2 0 Transketolase, pyrimidine binding domain DAGK_acc PF00609.19 OWF54263.1 - 7.7e-54 182.3 0.0 1.7e-53 181.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain RA PF00788.23 OWF54263.1 - 1.4e-30 105.8 0.0 7.8e-17 61.7 0.0 2.8 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 OWF54263.1 - 1.2e-26 92.3 46.3 2.6e-11 43.2 8.0 3.4 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.24 OWF54263.1 - 1.3e-23 83.0 0.0 2.6e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ufm1 PF03671.14 OWF54263.1 - 2.7e-06 27.4 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin fold modifier 1 protein TUG-UBL1 PF11470.8 OWF54263.1 - 0.00017 21.8 0.0 0.92 9.8 0.0 3.3 3 1 1 4 4 4 2 TUG ubiquitin-like domain Ras_bdg_2 PF14847.6 OWF54263.1 - 0.016 15.5 0.0 10 6.5 0.0 2.8 2 0 0 2 2 2 0 Ras-binding domain of Byr2 C1_2 PF03107.16 OWF54263.1 - 0.78 10.1 35.4 0.061 13.7 4.4 4.1 3 1 1 4 4 4 0 C1 domain PHD PF00628.29 OWF54263.1 - 1.4 8.9 38.1 0.23 11.4 8.0 4.1 4 0 0 4 4 4 0 PHD-finger Ribosomal_L5_C PF00673.21 OWF54264.1 - 7.8e-22 77.3 0.0 1.4e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OWF54264.1 - 9.3e-22 77.1 0.1 4e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 NYD-SP28 PF14772.6 OWF54265.1 - 1.1e-32 112.1 17.0 1.1e-32 112.1 17.0 6.3 4 1 1 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 OWF54265.1 - 2e-22 79.1 2.7 2e-22 79.1 2.7 4.1 2 1 2 4 4 4 1 Sperm tail C-terminal domain Mga PF05043.13 OWF54265.1 - 0.14 12.7 10.5 0.11 13.1 5.8 3.0 2 0 0 2 2 2 0 Mga helix-turn-helix domain 4HB_MCP_1 PF12729.7 OWF54266.1 - 0.11 12.1 0.3 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction WD40 PF00400.32 OWF54267.1 - 1e-52 174.9 6.2 2e-07 31.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF54267.1 - 1.6e-12 47.6 0.0 0.024 14.9 0.0 5.6 1 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF54267.1 - 1.5e-10 40.5 0.0 0.094 11.7 0.0 4.3 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OWF54267.1 - 9.1e-10 38.7 0.1 0.00087 19.2 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OWF54267.1 - 0.00073 18.2 0.3 0.31 9.5 0.1 3.0 1 1 1 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 OWF54267.1 - 0.0045 16.9 0.3 1.3 9.1 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 OWF54267.1 - 0.014 14.7 0.0 0.49 9.7 0.0 2.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 OWF54267.1 - 0.038 12.6 1.5 12 4.4 0.1 3.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OWF54267.1 - 0.13 12.8 0.9 31 5.2 0.1 3.3 2 1 1 3 3 3 0 PQQ-like domain SMN PF06003.12 OWF54268.1 - 1.6e-13 50.6 4.2 2e-13 50.2 4.2 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 OWF54268.1 - 2.6e-08 33.9 0.2 7.8e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Tudor domain Tudor_3 PF18115.1 OWF54268.1 - 3.9e-05 23.4 0.1 7.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF1325 PF07039.11 OWF54268.1 - 7.8e-05 22.8 0.2 7.8e-05 22.8 0.2 2.2 2 1 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 OWF54268.1 - 0.0002 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 OWF54268.1 - 0.0015 18.2 0.4 0.0031 17.2 0.4 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain EF-hand_7 PF13499.6 OWF54269.1 - 1.9e-29 101.9 4.7 1e-14 54.7 3.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF54269.1 - 1.2e-28 96.4 10.1 2.1e-07 30.0 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF54269.1 - 1.6e-24 83.7 6.0 2.1e-07 30.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF54269.1 - 8.5e-21 73.6 11.4 2.4e-11 43.3 1.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF54269.1 - 2.7e-19 67.7 11.9 2.8e-07 29.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 OWF54269.1 - 1e-05 25.4 2.9 0.12 12.4 0.7 2.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF54269.1 - 1.2e-05 25.6 0.0 0.028 14.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 OWF54269.1 - 0.00023 21.0 4.8 0.47 10.4 0.2 4.0 2 1 2 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 OWF54269.1 - 0.00035 20.9 0.3 0.0026 18.0 0.4 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF54269.1 - 0.018 15.9 0.1 0.18 12.7 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain DUF1456 PF07308.13 OWF54269.1 - 0.063 13.6 1.1 1.4 9.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) DUF3060 PF11259.8 OWF54270.1 - 0.18 11.5 45.6 0.99 9.2 3.4 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF3060) DUF3060 PF11259.8 OWF54271.1 - 1.6 8.5 57.2 1.6 8.5 2.6 7.6 2 2 6 9 9 9 0 Protein of unknown function (DUF3060) DUF302 PF03625.14 OWF54273.1 - 4.2e-05 23.3 2.3 19 5.2 0.1 5.7 1 1 7 8 8 8 5 Domain of unknown function DUF302 DUF4228 PF14009.6 OWF54273.1 - 5.2 7.4 5.9 3.8e+02 1.4 5.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) PH PF00169.29 OWF54274.1 - 2.9e-31 108.1 4.1 2.6e-17 63.2 0.2 2.9 3 0 0 3 3 3 2 PH domain PDZ_6 PF17820.1 OWF54274.1 - 2.3e-13 49.8 1.5 2.9e-13 49.4 0.4 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 OWF54274.1 - 5.5e-12 45.9 0.4 1.1e-11 44.9 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 OWF54274.1 - 2.5e-11 43.9 8.4 7.8e-06 26.3 3.5 3.7 2 1 0 2 2 2 2 Pleckstrin homology domain PDZ_2 PF13180.6 OWF54274.1 - 8.5e-08 32.4 0.2 2.2e-07 31.1 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PH_8 PF15409.6 OWF54274.1 - 3.4e-06 27.3 2.6 0.065 13.5 0.1 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 OWF54274.1 - 3e-05 24.4 2.6 0.31 11.4 0.8 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 OWF54274.1 - 0.0052 16.9 0.1 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 PH domain BCL_N PF04714.13 OWF54274.1 - 0.071 13.2 0.3 17 5.6 0.1 3.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region AC_N PF16214.5 OWF54274.1 - 0.26 10.4 2.6 0.6 9.2 2.6 1.6 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Tricorn_PDZ PF14685.6 OWF54274.1 - 0.44 10.5 1.8 0.49 10.4 0.2 1.8 2 0 0 2 2 2 0 Tricorn protease PDZ domain MRNIP PF15749.5 OWF54275.1 - 3.4e-23 82.4 21.3 3.4e-23 82.4 21.3 4.5 2 2 1 3 3 3 2 MRN-interacting protein zf-Sec23_Sec24 PF04810.15 OWF54275.1 - 0.37 10.9 4.6 4.2 7.5 3.7 2.8 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger FMP23 PF17315.2 OWF54275.1 - 5.5 7.1 5.9 6.7 6.9 2.1 2.2 2 0 0 2 2 2 0 Found in mitochondrial proteome EF-hand_7 PF13499.6 OWF54276.1 - 1.1e-12 48.3 8.8 4.2e-11 43.1 1.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF54276.1 - 4.2e-11 41.6 17.8 3.7e-07 29.2 0.4 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF54276.1 - 2.8e-10 39.9 7.0 0.00012 21.8 0.2 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OWF54276.1 - 4.6e-10 38.6 10.6 8.2e-05 22.2 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OWF54276.1 - 6.6e-07 28.5 0.1 6.6e-07 28.5 0.1 3.7 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 OWF54276.1 - 9.1e-07 29.2 0.2 1.9e-06 28.2 0.2 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF643 PF04867.12 OWF54276.1 - 0.015 15.9 0.7 0.024 15.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF643) Dockerin_1 PF00404.18 OWF54276.1 - 0.016 15.4 0.5 1.3 9.3 0.0 2.9 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_1 PF00036.32 OWF54277.1 - 8.7e-27 90.6 13.7 2.6e-06 26.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF54277.1 - 1e-25 88.0 6.8 3.2e-06 26.4 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF54277.1 - 2.2e-25 88.9 7.4 1.8e-12 47.5 1.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF54277.1 - 1.1e-21 74.8 8.3 5e-06 26.0 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF54277.1 - 8.4e-18 64.0 12.7 1.1e-08 34.7 0.7 3.6 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF54277.1 - 1.4e-07 31.8 1.5 0.0003 21.1 0.2 2.6 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OWF54277.1 - 0.0006 19.8 0.4 2.6 7.9 0.0 3.4 1 1 3 4 4 4 2 Caleosin related protein EF-hand_4 PF12763.7 OWF54277.1 - 0.0039 17.1 1.9 0.081 12.9 0.3 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 OWF54278.1 - 8.4e-29 96.9 14.4 2.9e-07 29.6 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF54278.1 - 2.2e-28 96.5 8.9 3.2e-06 26.4 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF54278.1 - 6.5e-27 93.8 7.1 3.1e-13 50.0 1.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF54278.1 - 1.7e-23 80.5 8.4 1.3e-06 27.8 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF54278.1 - 5.9e-18 64.5 14.6 1.9e-09 37.2 0.7 3.6 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF54278.1 - 2.6e-07 31.0 1.1 0.00053 20.3 0.2 2.6 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OWF54278.1 - 0.0026 17.7 0.4 14 5.6 0.0 3.4 1 1 2 4 4 4 1 Caleosin related protein EF-hand_9 PF14658.6 OWF54278.1 - 0.0066 16.8 0.7 0.7 10.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OWF54278.1 - 0.0073 16.2 2.3 0.089 12.8 0.4 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand PMBR PF09373.10 OWF54278.1 - 0.052 13.7 0.0 61 4.0 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat Dockerin_1 PF00404.18 OWF54278.1 - 0.082 13.1 3.1 18 5.6 0.0 3.4 4 0 0 4 4 4 0 Dockerin type I domain SBD PF17882.1 OWF54279.1 - 0.0099 15.7 0.2 10 5.9 0.0 3.7 1 1 1 2 2 2 2 OAA-family lectin sugar binding domain zf-CCCH_3 PF15663.5 OWF54279.1 - 5.8 7.2 43.5 1.6 9.0 0.6 7.4 1 1 6 7 7 7 0 Zinc-finger containing family SBD PF17882.1 OWF54280.1 - 0.01 15.7 0.1 3.7 7.4 0.1 2.7 1 1 2 3 3 3 3 OAA-family lectin sugar binding domain SF3A3 PF16837.5 OWF54280.1 - 0.24 12.0 0.2 34 5.1 0.0 3.6 2 2 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-CCCH_3 PF15663.5 OWF54280.1 - 0.5 10.6 24.0 1.7 8.9 3.3 5.2 2 2 1 4 4 4 0 Zinc-finger containing family PorP_SprF PF11751.8 OWF54282.1 - 0.044 13.3 1.5 0.63 9.5 0.3 1.9 1 1 1 2 2 2 0 Type IX secretion system membrane protein PorP/SprF Daxx PF03344.15 OWF54282.1 - 0.067 13.3 0.0 36 4.5 0.0 3.0 1 1 1 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain OMP_b-brl PF13505.6 OWF54282.1 - 0.11 12.6 0.4 9.6 6.3 0.1 2.1 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain 7tm_1 PF00001.21 OWF54283.1 - 1e-25 90.5 16.1 1.9e-25 89.7 16.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 OWF54283.1 - 0.00051 19.9 8.0 0.00051 19.9 8.0 2.9 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 DUF4834 PF16118.5 OWF54283.1 - 0.015 16.2 1.0 0.015 16.2 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) CCB1 PF12046.8 OWF54283.1 - 0.068 12.5 0.3 0.068 12.5 0.3 2.5 3 0 0 3 3 3 0 Cofactor assembly of complex C subunit B IPK PF03770.16 OWF54284.1 - 7e-41 140.3 0.1 1.1e-40 139.6 0.1 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase MFS_1 PF07690.16 OWF54285.1 - 9.8e-21 74.1 36.7 7.3e-12 44.9 9.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2798 PF11391.8 OWF54285.1 - 0.025 14.6 4.5 0.025 14.6 4.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2798) Chordopox_A13L PF05961.11 OWF54285.1 - 0.12 12.6 7.8 0.21 11.8 0.1 3.4 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Stevor PF17410.2 OWF54285.1 - 0.57 9.7 0.0 0.57 9.7 0.0 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Sigma_reg_N PF13800.6 OWF54285.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.0 4 1 0 4 4 4 0 Sigma factor regulator N-terminal DUF948 PF06103.11 OWF54285.1 - 4.5 7.6 4.9 64 3.9 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Bac_globin PF01152.21 OWF54286.1 - 5.8e-09 36.1 3.6 16 5.6 0.0 7.5 7 0 0 7 7 7 0 Bacterial-like globin Arm-DNA-bind_1 PF09003.10 OWF54286.1 - 1.5e-08 34.6 0.0 34 4.7 0.0 6.9 7 0 0 7 7 7 0 Bacteriophage lambda integrase, Arm DNA-binding domain Birna_VP3 PF01767.16 OWF54286.1 - 2.6e-08 34.3 0.0 12 5.9 0.0 6.7 7 0 0 7 7 7 1 Birnavirus VP3 protein WcbI PF18588.1 OWF54286.1 - 2.6e-07 30.5 0.4 6.2 6.4 0.0 5.8 6 0 0 6 6 6 2 Polysaccharide biosynthesis enzyme WcbI vATP-synt_AC39 PF01992.16 OWF54286.1 - 8.9e-07 28.7 0.3 1.2 8.6 0.0 6.4 7 0 0 7 7 7 1 ATP synthase (C/AC39) subunit PRKCSH-like PF12999.7 OWF54286.1 - 2.8e-05 24.0 6.3 11 5.7 0.0 6.8 7 0 0 7 7 7 1 Glucosidase II beta subunit-like DUF5497 PF17601.2 OWF54286.1 - 0.00012 22.4 9.4 40 4.6 0.0 6.9 7 0 0 7 7 7 0 Family of unknown function (DUF5497) HTH_DeoR PF08220.12 OWF54286.1 - 0.00071 19.3 0.0 26 4.7 0.0 5.4 6 0 0 6 6 6 0 DeoR-like helix-turn-helix domain YtxC PF08812.11 OWF54286.1 - 0.007 16.0 0.2 27 4.3 0.0 5.5 7 0 0 7 7 7 0 YtxC-like family DUF1836 PF08876.11 OWF54286.1 - 0.011 15.8 0.3 2e+02 2.1 0.0 5.6 7 0 0 7 7 7 0 Domain of unknown function (DUF1836) PerC PF06069.11 OWF54286.1 - 0.012 15.9 0.0 1.6e+02 2.6 0.0 5.5 7 0 0 7 7 7 0 PerC transcriptional activator Sec3_C PF09763.9 OWF54286.1 - 0.17 10.2 0.0 18 3.5 0.0 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec3 PolyG_pol PF01518.16 OWF54286.1 - 0.32 9.7 3.3 80 1.8 0.0 5.0 5 2 2 7 7 7 0 Sigma NS protein ANF_receptor PF01094.28 OWF54287.1 - 0.072 12.2 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Lipase_GDSL_2 PF13472.6 OWF54288.1 - 6.2e-06 26.7 0.0 9.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Nipped-B_C PF12830.7 OWF54289.1 - 0.062 13.2 2.1 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus ERM PF00769.19 OWF54289.1 - 0.58 9.9 26.5 0.22 11.3 22.0 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 OWF54289.1 - 6.7 7.0 26.4 0.32 11.2 8.0 4.1 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF1295 PF06966.12 OWF54290.1 - 3.7e-55 187.0 3.1 4.8e-55 186.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OWF54290.1 - 1.7e-07 31.3 0.8 3.5e-07 30.3 0.8 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OWF54290.1 - 0.04 14.3 0.3 0.12 12.8 0.3 1.8 1 0 0 1 1 1 0 Phospholipid methyltransferase Man-6-P_recep PF02157.15 OWF54291.1 - 3.3e-13 49.3 0.0 4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OWF54291.1 - 2.8e-12 47.1 0.0 3.7e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OWF54291.1 - 0.00017 21.7 0.0 0.016 15.2 0.1 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF2232 PF09991.9 OWF54291.1 - 0.023 13.9 0.6 0.031 13.5 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) HSP70 PF00012.20 OWF54292.1 - 5.2e-08 31.6 0.2 0.0014 16.9 0.2 2.3 1 1 1 2 2 2 2 Hsp70 protein DUF1413 PF07205.11 OWF54292.1 - 0.035 14.1 0.7 0.098 12.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) UPF0054 PF02130.17 OWF54293.1 - 1e-27 96.4 0.0 1.2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Pinin_SDK_N PF04697.13 OWF54294.1 - 0.45 11.2 3.3 0.6 10.7 3.3 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region DnaJ PF00226.31 OWF54295.1 - 4.6e-22 77.9 1.0 1.2e-21 76.6 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 OWF54295.1 - 2.3e-08 34.1 1.8 0.0093 16.1 0.0 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF54295.1 - 1.1e-06 28.8 6.4 0.01 16.1 2.5 4.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain PAS_8 PF13188.7 OWF54295.1 - 0.05 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain Anoct_dimer PF16178.5 OWF54295.1 - 0.088 12.5 6.7 0.12 12.1 5.8 1.7 1 1 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RAWUL PF16207.5 OWF54296.1 - 1.7e-16 60.6 0.3 3.6e-16 59.6 0.3 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 OWF54296.1 - 0.016 15.1 4.3 0.042 13.7 4.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF54296.1 - 0.052 13.9 4.4 0.11 12.8 4.4 1.6 1 0 0 1 1 1 0 Ring finger domain NUDE_C PF04880.13 OWF54296.1 - 0.18 12.2 11.2 0.51 10.8 11.2 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region zf-C3HC4_3 PF13920.6 OWF54296.1 - 0.33 10.8 7.9 0.058 13.3 4.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF54296.1 - 0.96 9.4 6.1 2.5 8.0 6.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF54296.1 - 3.1 7.7 6.9 1 9.3 3.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RAWUL PF16207.5 OWF54297.1 - 2e-18 66.8 0.1 5.2e-18 65.5 0.1 1.8 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 OWF54297.1 - 3.3e-10 39.6 5.4 6.3e-10 38.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF54297.1 - 3.1e-09 36.5 6.8 6.2e-09 35.6 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF54297.1 - 1.8e-06 28.1 6.3 3.7e-06 27.2 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OWF54297.1 - 9.5e-06 25.5 6.5 2.3e-05 24.2 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF54297.1 - 1.3e-05 25.0 7.3 2.5e-05 24.0 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF54297.1 - 0.00017 21.8 3.1 0.00045 20.4 3.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OWF54297.1 - 0.00059 19.6 5.4 0.0012 18.7 5.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OWF54297.1 - 0.022 14.8 8.9 0.023 14.7 6.4 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.6 OWF54297.1 - 0.031 14.4 0.6 0.08 13.1 0.6 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 OWF54297.1 - 0.055 13.6 10.8 0.11 12.7 9.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OWF54297.1 - 0.23 11.6 4.3 0.55 10.4 4.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 OWF54297.1 - 0.28 11.0 3.8 0.98 9.3 3.8 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 OWF54297.1 - 0.71 9.6 6.6 1.4 8.6 6.6 1.4 1 0 0 1 1 1 0 P-11 zinc finger Fer2 PF00111.27 OWF54297.1 - 1.1 9.2 3.9 14 5.7 2.4 2.9 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RAWUL PF16207.5 OWF54298.1 - 9.1e-13 48.7 0.2 2.1e-12 47.6 0.2 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 OWF54298.1 - 4.4e-08 32.8 9.8 1.4e-07 31.3 9.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF54298.1 - 1.8e-07 30.9 9.6 7.5e-07 28.9 9.6 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF54298.1 - 1.9e-05 24.9 9.2 9.1e-05 22.7 9.2 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF54298.1 - 4.9e-05 23.1 8.7 0.00015 21.5 8.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF54298.1 - 0.002 18.0 7.4 0.0075 16.1 7.4 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF54298.1 - 0.0078 16.2 10.9 0.0078 16.2 10.9 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 OWF54298.1 - 0.0088 16.2 5.1 0.032 14.4 5.1 2.0 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 OWF54298.1 - 0.013 15.8 6.7 0.013 15.8 6.7 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OWF54298.1 - 0.04 13.9 7.9 0.071 13.1 6.1 2.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF54298.1 - 0.046 13.9 10.4 0.26 11.5 10.4 2.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OWF54298.1 - 0.24 11.3 5.1 1.1 9.1 5.1 2.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ATG27 PF09451.10 OWF54299.1 - 3.9e-17 63.0 0.0 5.5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 OWF54299.1 - 2.5e-16 59.6 0.1 4.7e-16 58.7 0.0 1.4 2 0 0 2 2 2 1 Mannose-6-phosphate receptor EzrA PF06160.12 OWF54301.1 - 0.075 11.2 0.6 0.1 10.8 0.6 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RNA_pol_Rpb2_6 PF00562.28 OWF54302.1 - 2.4e-114 382.4 0.0 5.1e-114 381.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OWF54302.1 - 7.4e-37 126.8 0.1 1.1e-36 126.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OWF54302.1 - 6.2e-29 100.0 0.1 1.2e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 OWF54302.1 - 3.2e-22 78.7 0.1 8.7e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 OWF54302.1 - 3.9e-20 71.6 0.0 1.5e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 OWF54302.1 - 6.3e-14 52.0 0.0 1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 zf-Sec23_Sec24 PF04810.15 OWF54302.1 - 0.092 12.8 1.8 0.32 11.1 0.2 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Fringe PF02434.16 OWF54303.1 - 1e-11 44.8 0.3 7.1e-11 42.0 0.3 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF54303.1 - 9.8e-06 25.5 0.5 0.0075 16.1 0.2 2.5 1 1 1 2 2 2 2 Galactosyltransferase Glyco_trans_2_3 PF13632.6 OWF54303.1 - 0.031 14.2 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_25 PF01755.17 OWF54303.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Fringe PF02434.16 OWF54304.1 - 4.6e-11 42.6 0.7 3.3e-10 39.8 0.7 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF54304.1 - 8.7e-06 25.7 0.4 0.01 15.7 0.1 2.6 1 1 1 2 2 2 2 Galactosyltransferase Glyco_trans_2_3 PF13632.6 OWF54304.1 - 0.023 14.6 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_25 PF01755.17 OWF54304.1 - 0.066 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) MIP PF00230.20 OWF54305.1 - 0.0022 17.8 0.2 0.0036 17.0 0.2 1.5 1 0 0 1 1 1 1 Major intrinsic protein DUF4646 PF15496.6 OWF54306.1 - 0.016 15.8 0.0 0.031 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Plasmodium_HRP PF05403.11 OWF54307.1 - 6.8 6.4 62.2 2.8 7.7 26.5 2.0 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) RhoGEF PF00621.20 OWF54308.1 - 9.9e-22 78.0 1.3 2e-21 77.1 1.1 1.7 1 1 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 OWF54308.1 - 1.5e-13 50.8 0.3 4.7e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_5 PF15405.6 OWF54308.1 - 9.8e-07 28.9 0.9 1.6e-05 25.0 0.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 OWF54308.1 - 0.00056 19.7 1.1 0.0017 18.2 1.1 1.7 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 OWF54308.1 - 0.0061 16.8 0.2 0.013 15.8 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OWF54308.1 - 0.012 16.1 0.1 0.028 14.9 0.1 1.6 1 0 0 1 1 1 0 PH domain IQ_SEC7_PH PF16453.5 OWF54308.1 - 0.016 15.1 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 PH domain RhoGEF PF00621.20 OWF54309.1 - 5.1e-27 95.3 0.8 1.5e-26 93.8 0.5 2.0 1 1 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 OWF54309.1 - 1.4e-15 57.5 1.3 2.4e-14 53.4 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 OWF54309.1 - 1.6e-06 28.0 0.6 7.1e-06 25.9 0.6 2.2 1 1 0 1 1 1 1 PH domain PH_5 PF15405.6 OWF54309.1 - 3.1e-05 24.1 1.6 0.00059 19.9 0.4 3.0 2 1 1 3 3 3 1 Pleckstrin homology domain PH_10 PF15411.6 OWF54309.1 - 0.0041 17.4 0.1 0.012 15.9 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OWF54309.1 - 0.018 15.5 0.1 0.14 12.6 0.0 2.6 2 1 0 2 2 2 0 PH domain COG5 PF10392.9 OWF54309.1 - 0.022 14.9 0.1 0.078 13.1 0.1 1.9 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CCDC53 PF10152.9 OWF54309.1 - 0.08 13.4 3.1 0.16 12.3 3.1 1.7 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DivIC PF04977.15 OWF54309.1 - 0.32 10.8 6.4 0.13 12.1 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator SKICH PF17751.1 OWF54310.1 - 8.4e-07 29.5 16.2 3.1 8.4 0.0 9.4 4 2 7 12 12 12 1 SKICH domain DUF3082 PF11282.8 OWF54310.1 - 0.00041 20.5 20.7 1.3e+02 3.0 0.1 12.2 3 2 5 15 15 15 0 Protein of unknown function (DUF3082) PRE_C2HC PF07530.11 OWF54310.1 - 0.0031 17.6 1.1 12 6.1 0.1 5.9 7 0 0 7 7 7 1 Associated with zinc fingers Bmt2 PF11968.8 OWF54310.1 - 0.18 11.6 7.8 59 3.4 0.1 6.7 2 2 7 10 10 10 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Sulfotransfer_2 PF03567.14 OWF54311.1 - 7e-32 111.3 1.2 1.9e-30 106.6 0.2 2.2 2 0 0 2 2 2 2 Sulfotransferase family PI3K_C2 PF00792.24 OWF54311.1 - 0.0045 16.9 0.1 0.0089 16.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Glyco_hydro_20 PF00728.22 OWF54313.1 - 1.2e-49 169.7 0.0 1.5e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 OWF54313.1 - 3.5e-13 50.4 0.0 5.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 CHB_HEX PF03173.13 OWF54313.1 - 3.9e-12 46.1 0.0 7.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 OWF54313.1 - 0.0041 17.1 0.0 0.031 14.3 0.0 2.2 1 1 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain GHL10 PF02638.15 OWF54313.1 - 0.0045 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glycohydro_20b2 PF14845.6 OWF54313.1 - 0.031 14.9 0.0 0.06 14.0 0.0 1.5 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like Glyco_hydro_20 PF00728.22 OWF54314.1 - 2.9e-26 92.7 0.0 4e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 OWF54314.1 - 8.9e-17 61.2 0.0 2.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Putative carbohydrate binding domain Glyco_hydro_20b PF02838.15 OWF54314.1 - 8e-07 29.9 0.0 1.9e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 OWF54314.1 - 0.021 15.5 0.0 0.091 13.4 0.0 2.1 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like CHB_HEX_C PF03174.13 OWF54315.1 - 2e-05 24.5 0.1 9.4e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20 PF00728.22 OWF54315.1 - 0.016 14.6 0.2 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, catalytic domain PI3_PI4_kinase PF00454.27 OWF54317.1 - 0.002 18.0 19.3 15 5.3 0.1 7.3 1 1 6 7 7 7 4 Phosphatidylinositol 3- and 4-kinase Paramecium_SA PF01508.16 OWF54317.1 - 0.86 10.1 37.6 11 6.5 7.1 5.1 1 1 1 2 2 2 0 Paramecium surface antigen domain Crisp PF08562.10 OWF54317.1 - 5.7 7.6 37.3 37 5.0 1.4 6.3 1 1 7 8 8 8 0 Crisp Ig_3 PF13927.6 OWF54318.1 - 1.2e-184 599.4 159.4 4.8e-13 49.5 2.8 17.2 17 0 0 17 17 17 17 Immunoglobulin domain I-set PF07679.16 OWF54318.1 - 1.9e-166 540.7 73.8 6.7e-12 45.3 0.4 18.0 17 2 0 17 17 17 17 Immunoglobulin I-set domain ig PF00047.25 OWF54318.1 - 3e-128 418.3 133.7 9.4e-12 44.9 3.3 17.7 17 2 0 17 17 17 16 Immunoglobulin domain Ig_2 PF13895.6 OWF54318.1 - 1.3e-101 333.0 143.8 1.9e-08 34.5 3.4 17.3 17 0 0 17 17 17 17 Immunoglobulin domain V-set PF07686.17 OWF54318.1 - 1.2e-80 266.8 126.5 1.9e-06 28.0 0.7 24.5 17 14 1 18 18 17 15 Immunoglobulin V-set domain Ig_6 PF18452.1 OWF54318.1 - 1.2e-19 69.6 16.8 7.7 6.2 0.0 14.1 14 0 0 14 14 14 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF54318.1 - 1e-18 67.2 48.2 0.069 13.2 0.1 16.6 17 0 0 17 17 17 4 C17orf99 Ig domain Izumo-Ig PF16706.5 OWF54318.1 - 4e-16 58.8 7.0 0.23 11.5 0.0 13.9 16 0 0 16 16 16 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 OWF54318.1 - 3.3e-12 46.6 49.5 0.99 9.6 0.4 14.0 9 5 6 15 15 14 5 Natural killer cell receptor 2B4 Ig_4 PF16680.5 OWF54318.1 - 4e-11 43.0 26.0 2.6 8.4 0.0 16.2 17 3 0 17 17 17 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 OWF54318.1 - 1.3e-09 38.1 17.3 14 6.0 0.0 13.1 16 0 0 16 16 14 0 Immunoglobulin C2-set domain PKD_3 PF16820.5 OWF54318.1 - 5.1e-07 29.3 9.3 0.56 10.0 0.1 9.9 12 0 0 12 12 12 1 PKD-like domain Adeno_E3_CR1 PF02440.15 OWF54318.1 - 7.7e-06 25.6 86.1 0.0011 18.7 1.7 14.8 15 0 0 15 15 15 4 Adenovirus E3 region protein CR1 Herpes_gE PF02480.16 OWF54318.1 - 2.8e-05 23.1 48.0 0.07 11.9 0.1 12.5 6 5 6 14 14 14 3 Alphaherpesvirus glycoprotein E C1-set PF07654.15 OWF54318.1 - 3.7e-05 24.0 58.2 5.7 7.4 0.2 14.1 15 0 0 15 15 14 2 Immunoglobulin C1-set domain MucB_RseB_C PF17188.4 OWF54318.1 - 0.14 12.4 22.0 2.1 8.6 0.0 9.2 11 0 0 11 11 10 0 MucB/RseB C-terminal domain DUF4154 PF13689.6 OWF54318.1 - 0.15 12.3 1.0 38 4.5 0.0 4.1 4 0 0 4 4 4 0 YfiR/HmsC-like DUF5125 PF17163.4 OWF54318.1 - 0.16 12.1 19.0 2.4 8.3 0.7 4.7 2 1 1 4 4 4 0 Domain of unknown function (DUF5125) TMIE PF16038.5 OWF54318.1 - 0.5 10.2 3.7 0.96 9.3 3.7 1.4 1 0 0 1 1 1 0 TMIE protein Adeno_shaft PF00608.17 OWF54318.1 - 1.2 9.0 15.6 9.1 6.2 0.8 5.2 4 0 0 4 4 4 0 Adenoviral fibre protein (repeat/shaft region) V-set_2 PF15910.5 OWF54318.1 - 1.3 9.1 27.2 2.5 8.2 0.2 8.4 10 0 0 10 10 8 0 ICOS V-set domain Syndecan PF01034.20 OWF54318.1 - 5.4 7.0 6.4 1.4e+02 2.5 0.0 2.8 2 0 0 2 2 2 0 Syndecan domain DUF3727 PF12527.8 OWF54318.1 - 8.8 6.6 8.8 70 3.8 0.0 5.0 6 0 0 6 6 5 0 Protein of unknown function (DUF3727) SNF PF00209.18 OWF54320.1 - 2.5e-123 412.5 16.5 2.8e-123 412.4 16.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Myosin_tail_1 PF01576.19 OWF54321.1 - 1.5e-73 248.2 150.1 1.9e-73 247.9 150.1 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 OWF54321.1 - 2.9e-12 46.8 137.0 9e-06 25.5 10.2 7.8 1 1 4 6 6 6 4 Intermediate filament protein HALZ PF02183.18 OWF54321.1 - 2.1e-05 24.6 7.0 0.00012 22.2 1.1 12.7 12 1 2 14 14 13 2 Homeobox associated leucine zipper ADIP PF11559.8 OWF54321.1 - 9.3e-05 22.6 31.8 0.00033 20.8 12.8 10.7 1 1 10 12 12 12 4 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 OWF54321.1 - 0.00015 20.7 15.9 0.00015 20.7 15.9 7.6 2 2 5 7 7 7 3 Spc7 kinetochore protein HOOK PF05622.12 OWF54321.1 - 0.00021 19.6 31.6 0.00021 19.6 31.6 4.5 1 1 3 4 4 4 2 HOOK protein APG6_N PF17675.1 OWF54321.1 - 0.00029 21.4 10.1 0.00029 21.4 10.1 10.4 2 2 8 10 10 8 3 Apg6 coiled-coil region FAM184 PF15665.5 OWF54321.1 - 0.00064 19.6 33.7 0.002 17.9 15.3 7.1 2 1 5 7 7 7 4 Family with sequence similarity 184, A and B DUF1664 PF07889.12 OWF54321.1 - 0.00083 19.4 86.0 0.009 16.1 1.2 10.4 2 1 8 11 11 11 5 Protein of unknown function (DUF1664) ATG16 PF08614.11 OWF54321.1 - 0.0016 18.7 159.6 0.0044 17.3 23.0 8.7 1 1 8 9 9 8 5 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 OWF54321.1 - 0.0018 18.1 15.9 0.0018 18.1 15.9 8.6 1 1 7 8 8 8 4 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 OWF54321.1 - 0.002 18.0 1.5 0.002 18.0 1.5 11.9 7 5 6 14 14 14 1 GIT coiled-coil Rho guanine nucleotide exchange factor Phage_Mu_Gam PF07352.12 OWF54321.1 - 0.0038 17.2 3.3 0.0038 17.2 3.3 10.0 1 1 8 12 12 11 1 Bacteriophage Mu Gam like protein bZIP_1 PF00170.21 OWF54321.1 - 0.0048 17.0 1.5 0.0048 17.0 1.5 14.7 9 3 4 15 15 15 3 bZIP transcription factor Tropomyosin PF00261.20 OWF54321.1 - 0.0063 15.9 27.4 0.0063 15.9 27.4 8.4 1 1 6 7 7 3 1 Tropomyosin TPR_MLP1_2 PF07926.12 OWF54321.1 - 0.01 15.9 13.2 0.01 15.9 13.2 11.6 1 1 11 12 12 11 0 TPR/MLP1/MLP2-like protein Troponin PF00992.20 OWF54321.1 - 0.01 16.1 5.2 0.01 16.1 5.2 9.2 1 1 7 9 9 5 0 Troponin TolA_bind_tri PF16331.5 OWF54321.1 - 0.026 14.6 1.1 0.026 14.6 1.1 12.8 5 3 4 10 10 7 0 TolA binding protein trimerisation MbeD_MobD PF04899.12 OWF54321.1 - 0.064 13.4 0.1 0.064 13.4 0.1 11.1 7 5 3 10 10 10 0 MbeD/MobD like Shugoshin_N PF07558.11 OWF54321.1 - 0.087 12.7 0.1 0.087 12.7 0.1 10.9 9 1 3 12 12 12 0 Shugoshin N-terminal coiled-coil region AvrLm4-7 PF18661.1 OWF54321.1 - 0.11 13.5 5.5 15 6.7 0.1 4.8 3 1 1 4 4 4 0 Avirulence Effector AvrLm4-7 WCOR413 PF05562.11 OWF54322.1 - 0.28 11.1 4.2 11 5.9 0.7 3.1 1 1 1 3 3 3 0 Cold acclimation protein WCOR413 LSDAT_prok PF18171.1 OWF54322.1 - 0.53 9.5 2.9 7.2 5.8 0.6 2.8 1 1 2 3 3 3 0 SLOG in TRPM, prokaryote DUF746 PF05344.11 OWF54323.1 - 0.16 11.8 1.4 14 5.6 0.0 4.1 3 2 2 5 5 5 0 Domain of Unknown Function (DUF746) DUF1720 PF08226.11 OWF54323.1 - 4.7 7.7 41.3 1.8e+04 -4.6 41.3 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) DUF746 PF05344.11 OWF54324.1 - 0.016 15.0 0.0 8.7 6.3 0.0 2.7 1 1 2 3 3 3 0 Domain of Unknown Function (DUF746) Pex14_N PF04695.13 OWF54324.1 - 1.6 9.4 8.4 1.7 9.3 8.4 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2574 PF10836.8 OWF54324.1 - 4.1 7.4 5.9 8.7 6.3 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) LPD14 PF18827.1 OWF54326.1 - 0.002 18.4 2.1 2.5 8.4 0.0 4.1 1 1 1 3 3 3 2 Large polyvalent protein-associated domain 14 Lambda_CIII PF02061.16 OWF54326.1 - 0.065 13.3 23.8 27 4.9 0.0 10.2 6 4 3 9 9 9 0 Lambda Phage CIII Colicin_Pyocin PF01320.18 OWF54326.1 - 0.15 12.2 0.0 6.9 6.9 0.0 3.6 2 1 4 6 6 6 0 Colicin immunity protein / pyocin immunity protein Atg14 PF10186.9 OWF54326.1 - 0.16 11.0 2.3 6.7 5.7 0.4 3.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cu-oxidase_3 PF07732.15 OWF54327.1 - 1.4e-37 128.4 4.9 8.8e-37 125.7 1.6 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF54327.1 - 7.8e-29 100.2 15.4 9e-27 93.5 3.3 4.2 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF54327.1 - 2.6e-20 73.1 0.3 1.3e-19 70.8 0.1 2.3 2 1 0 2 2 2 1 Multicopper oxidase Complex1_49kDa PF00346.19 OWF54329.1 - 0.029 13.5 0.4 0.051 12.7 0.1 1.5 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF4407 PF14362.6 OWF54329.1 - 0.57 9.5 5.9 0.84 8.9 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UQ_con PF00179.26 OWF54330.1 - 5e-43 146.1 0.0 6.7e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 OWF54330.1 - 3.7e-11 42.7 0.0 7.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 OWF54330.1 - 7.5e-06 25.7 0.0 9.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OWF54330.1 - 0.0015 18.8 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 RWD domain UBA_4 PF14555.6 OWF54330.1 - 0.0087 15.9 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 OWF54330.1 - 0.12 12.1 0.5 0.46 10.3 0.5 1.9 1 1 0 1 1 1 0 CUE domain Pribosyltran_N PF13793.6 OWF54331.1 - 1.2e-47 160.6 0.9 3.7e-47 159.1 0.0 2.0 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OWF54331.1 - 1.3e-30 106.9 0.8 2.6e-23 83.0 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OWF54331.1 - 7.9e-15 54.7 0.7 1.6e-14 53.7 0.2 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OWF54331.1 - 8.8e-05 22.0 0.1 0.00015 21.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AtuA PF07287.11 OWF54332.1 - 5.8e-121 403.5 0.1 7.6e-121 403.1 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ARL2_Bind_BART PF11527.8 OWF54333.1 - 5.8e-14 52.2 1.5 8.3e-07 29.1 0.7 2.5 2 0 0 2 2 2 2 The ARF-like 2 binding protein BART P-mevalo_kinase PF04275.14 OWF54333.1 - 1.6 8.7 5.1 0.53 10.2 1.3 2.2 3 0 0 3 3 3 0 Phosphomevalonate kinase Sas10_Utp3 PF04000.15 OWF54334.1 - 5.6e-15 55.7 0.6 9.8e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family PDZ PF00595.24 OWF54335.1 - 3.5e-05 24.0 0.1 0.00013 22.2 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 OWF54335.1 - 0.028 14.7 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 PDZ domain Phage_holin_3_6 PF07332.11 OWF54335.1 - 0.13 12.3 0.3 0.21 11.6 0.3 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Tetraspanin PF00335.20 OWF54335.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family SKG6 PF08693.10 OWF54335.1 - 0.35 10.3 5.0 0.84 9.1 5.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 3HCDH_N PF02737.18 OWF54336.1 - 1.5e-37 129.3 0.0 2.2e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_3 PF13920.6 OWF54336.1 - 5e-13 48.7 15.7 5e-13 48.7 15.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NAD_binding_2 PF03446.15 OWF54336.1 - 2.9e-07 30.8 0.0 2.8e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 OWF54336.1 - 3.8e-05 23.7 0.0 5.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Prok-RING_4 PF14447.6 OWF54336.1 - 8.7e-05 22.3 14.2 0.00018 21.3 14.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UDPG_MGDP_dh_N PF03721.14 OWF54336.1 - 0.00024 20.8 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 OWF54336.1 - 0.00026 21.5 0.2 0.00059 20.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf-RING_2 PF13639.6 OWF54336.1 - 0.00038 20.7 18.2 0.00038 20.7 18.2 1.8 2 0 0 2 2 2 1 Ring finger domain F420_oxidored PF03807.17 OWF54336.1 - 0.0014 19.2 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 OWF54336.1 - 0.0033 16.7 0.1 0.005 16.2 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OWF54336.1 - 0.016 14.5 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_5 PF14634.6 OWF54336.1 - 0.038 14.0 16.3 0.085 12.8 16.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain UDPG_MGDP_dh_C PF03720.15 OWF54336.1 - 0.058 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 OWF54336.1 - 0.06 13.0 0.1 0.097 12.3 0.1 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OWF54336.1 - 0.12 12.4 1.2 1.3 9.1 0.7 2.5 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-C3HC4_2 PF13923.6 OWF54336.1 - 0.28 11.1 23.8 0.037 13.9 18.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OWF54336.1 - 1.6 8.6 15.5 4.2 7.2 15.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Methyltransf_16 PF10294.9 OWF54337.1 - 7.2e-18 64.9 0.0 9.5e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 OWF54337.1 - 0.0098 16.5 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF54337.1 - 0.01 16.6 0.0 0.018 15.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OWF54337.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OWF54337.1 - 0.043 14.5 0.0 0.082 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OWF54337.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Steroid_dh PF02544.16 OWF54338.1 - 3.3e-55 186.2 0.4 3.3e-55 186.2 0.4 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OWF54338.1 - 1.3e-06 28.1 0.1 1.3e-06 28.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) TPR_11 PF13414.6 OWF54339.1 - 7e-05 22.4 0.5 0.086 12.5 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 OWF54339.1 - 0.00011 21.9 1.2 0.63 10.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF54339.1 - 0.00027 20.8 2.2 0.98 9.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat NUDE_C PF04880.13 OWF54339.1 - 0.0039 17.7 0.3 0.0073 16.8 0.3 1.4 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region TPR_8 PF13181.6 OWF54339.1 - 0.0055 16.8 1.1 1 9.7 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF54339.1 - 0.021 15.3 0.0 0.25 11.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DivIC PF04977.15 OWF54339.1 - 0.024 14.4 3.4 0.049 13.4 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator gpW PF02831.15 OWF54339.1 - 0.025 14.5 0.1 0.056 13.3 0.1 1.6 1 0 0 1 1 1 0 gpW Syntaxin PF00804.25 OWF54339.1 - 0.028 14.1 0.5 0.14 11.8 0.1 2.2 3 0 0 3 3 3 0 Syntaxin DUF4618 PF15397.6 OWF54339.1 - 0.057 12.8 0.5 0.12 11.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) T2SSM PF04612.12 OWF54339.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CENP-H PF05837.12 OWF54339.1 - 0.081 13.3 1.9 0.083 13.3 0.1 1.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) ABC_tran_CTD PF16326.5 OWF54339.1 - 0.1 12.8 0.6 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spc24 PF08286.11 OWF54339.1 - 0.19 12.0 2.5 1.5 9.1 0.1 2.9 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 DUF5082 PF16888.5 OWF54339.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.0 3 0 0 3 3 2 0 Domain of unknown function (DUF5082) SlyX PF04102.12 OWF54339.1 - 0.49 11.1 2.7 0.59 10.8 0.1 2.2 2 0 0 2 2 2 0 SlyX ADIP PF11559.8 OWF54339.1 - 0.52 10.4 3.4 0.87 9.7 0.5 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 OWF54339.1 - 0.74 10.3 3.6 0.68 10.4 0.7 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ZapB PF06005.12 OWF54339.1 - 0.88 10.1 5.3 3.7 8.1 5.3 2.0 1 1 0 1 1 1 0 Cell division protein ZapB FHA PF00498.26 OWF54340.1 - 1.2e-18 67.2 0.0 4.4e-18 65.4 0.0 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OWF54340.1 - 4.1e-06 27.0 0.0 1.8e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dicer_dimer PF03368.14 OWF54340.1 - 2.2e-05 24.5 0.0 0.00013 22.1 0.0 2.3 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 OWF54340.1 - 0.12 13.0 0.0 0.12 13.0 0.0 2.9 3 0 0 3 3 3 0 Double-stranded RNA binding motif Transglut_core PF01841.19 OWF54341.1 - 0.00047 20.6 0.0 0.0016 18.9 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 OWF54341.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like domain C2 PF00168.30 OWF54342.1 - 2.9e-29 101.4 0.1 2.8e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain zf-C2H2_jaz PF12171.8 OWF54343.1 - 0.03 14.6 5.1 22 5.5 0.0 4.5 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding SRCR PF00530.18 OWF54343.1 - 0.15 12.6 4.6 1 9.9 2.7 2.4 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain Phage_tail_U PF06141.11 OWF54343.1 - 0.38 11.1 1.5 41 4.5 0.1 3.2 1 1 2 3 3 3 0 Phage minor tail protein U DUF1187 PF06688.11 OWF54343.1 - 0.63 10.4 5.2 7.2 7.0 0.2 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1187) UPF0506 PF11703.8 OWF54343.1 - 2.4 8.6 8.8 5.5 7.5 2.4 3.0 2 1 1 3 3 3 0 UPF0506 CBX7_C PF17218.3 OWF54343.1 - 3.8 7.3 13.0 1.6 8.5 0.5 4.4 4 2 2 6 6 6 0 CBX family C-terminal motif ClpS PF02617.17 OWF54344.1 - 1.6e-22 79.0 0.6 5.9e-22 77.2 0.3 2.2 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 OWF54344.1 - 3.2e-22 78.5 11.6 3.2e-22 78.5 11.6 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-C3HC4_2 PF13923.6 OWF54344.1 - 0.028 14.2 0.2 0.028 14.2 0.2 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OWF54344.1 - 0.038 13.6 0.2 0.038 13.6 0.2 3.7 5 0 0 5 5 5 0 Zinc-ribbon, C4HC2 type DUF4239 PF14023.6 OWF54344.1 - 0.08 12.7 0.2 14 5.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) SIX1_SD PF16878.5 OWF54346.1 - 1.1e-47 161.2 0.1 1.1e-47 161.2 0.1 2.7 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 OWF54346.1 - 6.9e-15 54.6 1.8 6.9e-15 54.6 1.8 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF54346.1 - 7e-10 38.7 1.5 1.7e-09 37.4 1.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OWF54346.1 - 0.0063 16.0 0.2 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez DUF2796 PF10986.8 OWF54346.1 - 0.049 13.6 12.7 0.09 12.7 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) YdaS_antitoxin PF15943.5 OWF54346.1 - 0.072 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SelP_N PF04592.14 OWF54346.1 - 0.074 12.5 15.8 0.14 11.6 15.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region 5_3_exonuc_N PF02739.16 OWF54346.1 - 0.18 11.7 0.1 0.42 10.5 0.1 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Hydin_ADK PF17213.3 OWF54346.1 - 1.7 8.9 4.1 0.53 10.5 0.4 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain MGC-24 PF05283.11 OWF54346.1 - 7.5 7.0 6.4 16 6.0 6.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin COMMD1_N PF17221.3 OWF54347.1 - 2e-18 66.6 2.4 5.8e-18 65.1 0.6 2.1 2 0 0 2 2 2 1 COMMD1 N-terminal domain COMM_domain PF07258.14 OWF54347.1 - 1.6e-16 60.1 3.8 2.5e-16 59.5 3.8 1.3 1 0 0 1 1 1 1 COMM domain COMMD1_N PF17221.3 OWF54348.1 - 1.1e-16 60.9 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 COMMD1 N-terminal domain SPOB_ab PF14682.6 OWF54348.1 - 0.048 13.7 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal SPG48 PF14764.6 OWF54349.1 - 0.18 12.3 7.7 0.62 10.5 1.8 3.6 3 0 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking MTA_R1 PF17226.2 OWF54350.1 - 2e-29 101.5 3.7 2.6e-29 101.2 1.7 2.3 2 0 0 2 2 2 1 MTA R1 domain BAH PF01426.18 OWF54350.1 - 3.4e-28 98.0 0.5 1e-26 93.2 0.5 2.7 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 OWF54350.1 - 1.4e-15 57.8 0.0 4.4e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.27 OWF54350.1 - 4.4e-08 32.6 7.2 1.1e-07 31.3 7.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 OWF54350.1 - 5.5e-06 26.5 0.1 1.4e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2 PF00096.26 OWF54350.1 - 0.0075 16.7 0.7 0.0075 16.7 0.7 2.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type Myb_DNA-bind_7 PF15963.5 OWF54350.1 - 0.014 15.3 0.2 0.038 13.9 0.2 1.7 1 0 0 1 1 1 0 Myb DNA-binding like SNF2_N PF00176.23 OWF54351.1 - 7.4e-31 107.1 0.0 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF54351.1 - 3e-12 46.8 0.0 2.6e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HNH PF01844.23 OWF54351.1 - 3.5e-07 30.3 0.1 3.5e-07 30.3 0.1 4.1 5 0 0 5 5 5 1 HNH endonuclease ResIII PF04851.15 OWF54351.1 - 9.9e-07 28.9 0.0 4.9e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HNH_5 PF14279.6 OWF54351.1 - 0.0039 17.0 3.0 0.03 14.2 0.1 3.1 2 0 0 2 2 2 1 HNH endonuclease zf-RanBP PF00641.18 OWF54351.1 - 0.0087 15.4 4.5 0.032 13.5 2.3 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others AAA_22 PF13401.6 OWF54351.1 - 0.028 14.7 0.1 0.31 11.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain PI-PLC-X PF00388.19 OWF54352.1 - 4.7e-63 211.1 0.0 4.7e-63 211.1 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PH_14 PF17787.1 OWF54352.1 - 6e-42 142.6 0.0 1.6e-41 141.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PI-PLC-Y PF00387.19 OWF54352.1 - 6.2e-35 120.0 0.0 6.2e-35 120.0 0.0 3.5 4 0 0 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 OWF54352.1 - 6.9e-14 52.1 0.2 6.9e-14 52.1 0.2 2.8 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like PLC-beta_C PF08703.10 OWF54352.1 - 2.7e-13 50.3 33.2 2.7e-13 50.3 33.2 2.8 2 1 1 3 3 3 1 PLC-beta C terminal DUF1154 PF06631.11 OWF54352.1 - 2.7e-08 33.7 6.2 2.7e-08 33.7 6.2 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1154) DUF4813 PF16072.5 OWF54352.1 - 3.5 7.2 4.6 5.6 6.5 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Metallophos PF00149.28 OWF54353.1 - 7.9e-40 137.5 0.1 1e-39 137.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OWF54353.1 - 1.4e-21 76.6 0.4 3.5e-21 75.4 0.4 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Beta_helix PF13229.6 OWF54354.1 - 3.6e-96 319.4 88.1 5e-27 94.7 16.3 4.7 1 1 5 6 6 6 5 Right handed beta helix region NosD PF05048.13 OWF54354.1 - 9.6e-39 133.1 32.8 1.5e-14 53.9 8.7 4.3 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) zf-UBR PF02207.20 OWF54354.1 - 1e-09 38.4 13.1 2.5e-09 37.2 13.1 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Peptidase_C31 PF05410.13 OWF54354.1 - 0.084 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha EF-hand_7 PF13499.6 OWF54355.1 - 1.3e-15 57.5 0.2 5.8e-11 42.7 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF54355.1 - 7e-15 53.6 0.5 0.00015 21.5 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 OWF54355.1 - 2.9e-13 48.3 0.9 5.7e-06 25.5 0.2 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF54355.1 - 1.8e-11 43.7 0.8 2.4e-06 27.3 0.0 3.7 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF54355.1 - 7.4e-08 31.5 4.8 0.00019 20.8 0.1 4.1 4 1 1 5 5 5 2 EF hand CCD48 PF15799.5 OWF54355.1 - 0.022 13.1 0.1 0.13 10.6 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 EF-hand_9 PF14658.6 OWF54355.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain PTPA PF03095.15 OWF54357.1 - 5.5e-68 229.6 0.1 2.3e-50 171.8 0.0 2.1 1 1 0 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein Abhydrolase_6 PF12697.7 OWF54358.1 - 6.9e-07 30.1 0.0 8.9e-05 23.2 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OWF54358.1 - 5.9e-06 26.1 0.0 0.03 13.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OWF54358.1 - 0.0019 17.5 0.0 0.61 9.3 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 IN_DBD_C PF00552.21 OWF54358.1 - 0.055 12.8 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Integrase DNA binding domain CASP_C PF08172.12 OWF54359.1 - 6.3e-07 29.0 1.2 8.8e-07 28.5 1.2 1.2 1 0 0 1 1 1 1 CASP C terminal Nodulin_late PF07127.11 OWF54359.1 - 0.0026 18.1 2.4 0.0026 18.1 2.4 3.0 1 1 3 4 4 4 1 Late nodulin protein DNA_pol_A_exo1 PF01612.20 OWF54359.1 - 0.14 11.9 4.3 9 6.0 0.9 2.8 1 1 1 2 2 2 0 3'-5' exonuclease Fer4_20 PF14691.6 OWF54359.1 - 0.26 11.1 7.4 5.4 6.8 0.6 3.0 1 1 2 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Calcyon PF06387.11 OWF54359.1 - 0.33 10.9 2.2 0.32 11.0 0.7 1.6 1 1 1 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) Ephrin_rec_like PF07699.13 OWF54359.1 - 0.41 10.4 0.1 0.41 10.4 0.1 3.4 3 1 0 3 3 3 0 Putative ephrin-receptor like Glycolytic PF00274.19 OWF54360.1 - 3.7e-180 598.2 0.0 4.2e-180 598.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.19 OWF54361.1 - 1e-167 557.3 0.0 1.3e-167 556.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I FYVE_2 PF02318.16 OWF54362.1 - 2.2e-34 118.2 4.3 3.5e-34 117.6 4.3 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 OWF54362.1 - 0.0055 16.8 11.5 0.013 15.6 11.5 1.7 1 1 0 1 1 1 1 Piccolo Zn-finger FYVE PF01363.21 OWF54362.1 - 0.2 11.8 7.2 0.56 10.4 7.2 1.8 1 1 0 1 1 1 0 FYVE zinc finger Macoilin PF09726.9 OWF54362.1 - 8.4 4.8 7.4 12 4.4 7.4 1.1 1 0 0 1 1 1 0 Macoilin family Plasmod_MYXSPDY PF07981.11 OWF54363.1 - 7 6.8 7.5 1.4e+02 2.7 0.1 4.1 4 0 0 4 4 4 0 Plasmodium repeat_MYXSPDY C2 PF00168.30 OWF54364.1 - 1.4e-36 124.9 0.0 3.7e-22 78.6 0.0 2.7 2 1 0 2 2 2 2 C2 domain Lipocalin_7 PF14651.6 OWF54365.1 - 1.2e-07 31.7 2.7 1.9e-07 31.1 2.7 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.6 OWF54365.1 - 0.3 12.1 6.3 0.92 10.5 6.3 1.8 1 1 0 1 1 1 0 Lipocalin-like domain CH PF00307.31 OWF54366.1 - 7.5e-21 74.4 0.4 6.1e-20 71.4 0.0 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OWF54366.1 - 2.3e-06 27.4 0.0 9.7e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain DUF2937 PF11157.8 OWF54366.1 - 0.18 11.5 3.1 2.2 7.9 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) ERM PF00769.19 OWF54366.1 - 2.1 8.1 80.9 1.9 8.2 36.1 5.0 3 1 2 5 5 5 0 Ezrin/radixin/moesin family GIT_CC PF16559.5 OWF54366.1 - 4.2 7.3 31.5 0.076 12.9 3.0 5.6 5 0 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 OWF54366.1 - 4.8 7.2 90.1 0.034 14.2 5.0 5.9 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Metallopep PF12044.8 OWF54367.1 - 5.4e-83 279.0 0.4 7.6e-83 278.5 0.4 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 OWF54367.1 - 0.0098 16.1 0.1 0.025 14.7 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF54367.1 - 0.07 13.6 0.2 0.2 12.2 0.2 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Pns11_12 PF17464.2 OWF54367.1 - 0.073 12.8 2.4 0.16 11.7 2.4 1.5 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Pex14_N PF04695.13 OWF54367.1 - 0.67 10.6 4.3 12 6.6 4.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Noggin PF05806.12 OWF54368.1 - 0.057 13.3 11.2 0.57 10.1 4.8 2.3 1 1 0 2 2 2 0 Noggin REV PF00424.18 OWF54368.1 - 2.5 8.2 7.1 5 7.2 0.3 2.7 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) 7tm_1 PF00001.21 OWF54370.1 - 5.1e-60 203.0 23.6 8e-60 202.4 23.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF54370.1 - 0.0024 17.7 24.8 0.012 15.4 24.8 2.0 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 OWF54370.1 - 0.14 11.4 18.8 0.68 9.1 18.8 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw PLAC8 PF04749.17 OWF54370.1 - 0.56 11.2 0.1 0.56 11.2 0.1 3.2 3 1 0 3 3 3 0 PLAC8 family 2C_adapt PF08793.10 OWF54371.1 - 0.047 13.9 0.3 0.18 12.0 0.3 2.0 1 0 0 1 1 1 0 2-cysteine adaptor domain Urb2 PF10441.9 OWF54372.1 - 7.1e-20 71.8 0.7 7.1e-20 71.8 0.7 3.8 4 1 0 4 4 4 1 Urb2/Npa2 family RB_B PF01857.20 OWF54372.1 - 0.42 10.7 2.3 13 5.8 0.3 3.9 3 0 0 3 3 3 0 Retinoblastoma-associated protein B domain ComR_TPR PF18710.1 OWF54375.1 - 0.092 12.3 0.9 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 ComR tetratricopeptide Ig_Tie2_1 PF10430.9 OWF54375.1 - 0.1 13.0 0.0 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Kelch_3 PF13415.6 OWF54376.1 - 0.68 10.3 13.3 43 4.5 0.9 6.2 1 1 2 3 3 3 0 Galactose oxidase, central domain Sigma70_r2 PF04542.14 OWF54376.1 - 1 9.2 4.2 2.6 7.9 0.1 3.0 2 2 1 3 3 3 0 Sigma-70 region 2 Maf1 PF09174.10 OWF54376.1 - 3.1 7.9 17.3 9.3 6.4 0.4 4.5 1 1 3 4 4 4 0 Maf1 regulator AHJR-like PF18743.1 OWF54376.1 - 4.9 6.7 11.8 23 4.6 0.1 5.5 1 1 5 6 6 6 0 REase_AHJR-like ComR_TPR PF18710.1 OWF54378.1 - 0.0063 16.1 0.6 1.4 8.4 0.1 2.4 2 0 0 2 2 2 2 ComR tetratricopeptide Ig_Tie2_1 PF10430.9 OWF54378.1 - 0.081 13.4 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 DUF5448 PF17526.2 OWF54378.1 - 0.35 11.1 2.8 6.4 7.0 0.1 3.1 2 1 0 3 3 3 0 Family of unknown function (DUF5448) HLH PF00010.26 OWF54379.1 - 2.4e-15 56.2 0.2 3.5e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tubulin PF00091.25 OWF54380.1 - 3.8e-69 232.9 0.0 6.5e-69 232.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF54380.1 - 3.9e-43 146.6 0.1 6.3e-43 145.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OWF54380.1 - 1.2e-05 25.6 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OWF54380.1 - 0.0081 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OWF54380.1 - 0.02 14.1 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Oxysterol_BP PF01237.18 OWF54381.1 - 8.4e-82 275.0 4.4 2.8e-79 266.6 4.4 2.4 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 OWF54381.1 - 2.1e-14 53.9 0.0 4.9e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OWF54381.1 - 8.5e-08 32.4 0.2 1.7e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OWF54381.1 - 1.6e-06 28.4 2.1 2.9e-05 24.5 2.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 OWF54381.1 - 0.0019 18.5 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 OWF54381.1 - 0.0034 17.2 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_4 PF12763.7 OWF54382.1 - 5.2e-37 126.0 0.0 4e-24 84.6 0.0 4.1 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 OWF54382.1 - 1.3e-12 46.3 0.5 0.00051 19.4 0.1 4.9 5 0 0 5 5 5 3 EF hand DEP PF00610.21 OWF54382.1 - 2.8e-09 36.9 0.0 8.7e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_6 PF13405.6 OWF54382.1 - 4.8e-08 32.3 1.3 0.24 11.4 0.0 5.0 5 0 0 5 5 4 2 EF-hand domain EF-hand_7 PF13499.6 OWF54382.1 - 5.1e-07 30.1 0.0 0.058 13.8 0.0 4.6 3 1 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF54382.1 - 1e-05 24.8 2.3 0.22 11.1 0.4 3.6 4 0 0 4 4 4 2 EF hand RhoGAP PF00620.27 OWF54382.1 - 0.00031 20.6 4.7 0.27 11.0 0.2 3.1 3 0 0 3 3 3 2 RhoGAP domain EF-hand_8 PF13833.6 OWF54382.1 - 0.00056 19.7 1.5 0.24 11.3 0.2 3.3 3 0 0 3 3 3 1 EF-hand domain pair CENP-F_leu_zip PF10473.9 OWF54382.1 - 0.076 13.0 40.1 0.47 10.5 28.9 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 OWF54382.1 - 0.11 12.3 29.5 0.025 14.4 25.4 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 OWF54382.1 - 0.37 9.4 16.9 0.78 8.3 16.9 1.5 1 0 0 1 1 1 0 AAA domain DUF2730 PF10805.8 OWF54382.1 - 0.47 10.6 17.3 0.077 13.1 9.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 OWF54382.1 - 0.7 10.2 21.7 0.077 13.3 14.5 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 OWF54382.1 - 1.6 8.0 30.1 0.016 14.5 16.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TRAF_BIRC3_bd PF16673.5 OWF54382.1 - 5 7.0 10.7 0.49 10.2 2.3 2.6 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF4164 PF13747.6 OWF54382.1 - 5 7.5 25.4 0.49 10.7 7.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) UPF0242 PF06785.11 OWF54382.1 - 9.4 6.3 45.5 1.3 9.1 22.5 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 OWF54383.1 - 6e-11 42.7 1.1 0.011 16.5 0.1 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF54383.1 - 2.7e-10 40.4 0.0 0.23 11.8 0.0 5.6 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OWF54383.1 - 5.2e-07 28.5 0.0 1.6e-06 26.9 0.0 1.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 OWF54383.1 - 0.0051 16.7 0.0 3 7.9 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OWF54383.1 - 0.072 12.0 0.1 0.22 10.5 0.0 1.8 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CpeT PF06206.11 OWF54383.1 - 0.12 12.3 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) Hira PF07569.11 OWF54383.1 - 0.13 11.9 0.2 15 5.2 0.0 2.9 2 1 0 3 3 3 0 TUP1-like enhancer of split DUF5563 PF17718.1 OWF54384.1 - 0.014 15.0 0.0 8.3 5.9 0.0 3.1 1 1 3 4 4 4 0 Family of unknown function (DUF5563) Nmad3 PF18754.1 OWF54384.1 - 0.087 12.4 0.0 6 6.4 0.0 3.2 1 1 0 1 1 1 0 Nucleotide modification associated domain 3 MHYT PF03707.16 OWF54384.1 - 1.4 9.1 7.8 51 4.1 0.0 4.5 5 0 0 5 5 5 0 Bacterial signalling protein N terminal repeat Branch PF02485.21 OWF54385.1 - 9e-36 123.6 0.1 1.2e-35 123.2 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Rhabdo_M1 PF03342.13 OWF54386.1 - 9.7 5.5 11.3 2.8e+02 0.7 0.0 6.2 1 1 6 9 9 9 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) PKHD_C PF18331.1 OWF54387.1 - 0.14 12.2 0.2 0.72 10.0 0.2 2.2 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain F5_F8_type_C PF00754.25 OWF54388.1 - 4.4e-57 191.7 9.8 4.6e-28 97.9 0.5 3.3 3 0 0 3 3 3 3 F5/8 type C domain DUF3947 PF13135.6 OWF54388.1 - 0.074 13.2 0.6 0.33 11.2 0.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3947) SLATT_fungal PF18142.1 OWF54388.1 - 0.29 11.1 4.1 0.82 9.7 4.1 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain F5_F8_type_C PF00754.25 OWF54389.1 - 3.4e-09 36.9 0.0 3.7e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Crisp PF08562.10 OWF54391.1 - 0.02 15.5 4.0 2.6 8.7 0.3 2.2 2 0 0 2 2 2 0 Crisp PIF1 PF05970.14 OWF54393.1 - 1.8e-70 238.0 1.3 6.7e-51 173.6 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 OWF54393.1 - 2.8e-19 69.6 0.0 4.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF54393.1 - 7.3e-07 29.6 0.0 2.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OWF54393.1 - 9.3e-05 22.2 0.0 0.00026 20.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 OWF54393.1 - 0.00098 19.4 0.1 0.0042 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 OWF54393.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 OWF54393.1 - 0.0027 17.5 0.1 3.5 7.3 0.0 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 OWF54393.1 - 0.0034 16.8 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Herpes_Helicase PF02689.14 OWF54393.1 - 0.0047 14.9 0.1 0.014 13.4 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA_5 PF07728.14 OWF54393.1 - 0.0049 16.9 0.0 0.015 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OWF54393.1 - 0.008 15.7 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OWF54393.1 - 0.01 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OWF54393.1 - 0.041 12.9 0.0 0.088 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 OWF54393.1 - 0.042 13.8 0.0 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA PF00004.29 OWF54393.1 - 0.09 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flu_C_NS2 PF03555.14 OWF54393.1 - 0.092 12.9 0.4 0.4 10.9 0.1 2.3 3 0 0 3 3 1 0 Influenza C non-structural protein (NS2) ABC_tran PF00005.27 OWF54393.1 - 0.093 13.2 0.0 0.33 11.5 0.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OWF54393.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OWF54393.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OWF54393.1 - 0.19 11.5 0.1 0.45 10.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 OWF54393.1 - 4.6 6.9 7.7 13 5.5 0.0 3.0 4 0 0 4 4 4 0 AAA domain TPR_2 PF07719.17 OWF54394.1 - 6.6e-06 25.9 0.0 0.022 14.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF54394.1 - 9.7e-05 22.0 0.0 0.03 14.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF54394.1 - 0.00012 21.7 0.0 0.038 13.7 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 OWF54394.1 - 0.019 15.1 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OWF54394.1 - 0.033 14.8 0.0 1.8 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OWF54394.1 - 0.17 12.8 0.7 3.9 8.6 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TRIC PF05197.13 OWF54395.1 - 5.7e-82 274.0 2.5 8e-82 273.5 2.5 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 OWF54395.1 - 0.11 12.4 2.2 5.3 7.0 0.0 2.8 3 1 0 3 3 3 0 UPF0126 domain MCD_N PF17408.2 OWF54396.1 - 0.0067 16.5 2.0 1.1 9.4 0.2 2.2 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase N-terminal domain AAA_lid_4 PF17864.1 OWF54396.1 - 0.14 11.9 3.4 5.3 6.9 0.2 2.4 2 1 1 3 3 3 0 RuvB AAA lid domain GNT-I PF03071.15 OWF54397.1 - 1.3e-48 165.8 3.5 1.3e-47 162.6 3.5 2.1 1 1 0 1 1 1 1 GNT-I family ILEI PF15711.5 OWF54397.1 - 3.5e-27 94.7 0.2 1.5e-26 92.7 0.1 2.2 2 0 0 2 2 2 1 Interleukin-like EMT inducer Tetraspanin PF00335.20 OWF54397.1 - 0.071 12.8 0.1 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Tetraspanin family CABIT PF12736.7 OWF54398.1 - 3e-36 125.2 0.0 4.6e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, DNA_pol3_delta PF06144.13 OWF54398.1 - 0.17 11.7 1.5 0.27 11.0 1.5 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PDEase_I PF00233.19 OWF54399.1 - 7.5e-75 251.7 4.4 8.2e-75 251.6 3.1 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OWF54399.1 - 7.3e-22 78.4 0.0 1.8e-15 57.7 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 OWF54399.1 - 9.1e-17 61.6 0.0 7.4e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 OWF54399.1 - 3.5e-09 37.1 0.0 1.2e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 OWF54399.1 - 0.011 15.8 0.0 0.072 13.1 0.0 2.3 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor Stathmin PF00836.19 OWF54400.1 - 1.7e-07 31.3 33.8 1.7e-07 31.3 33.8 2.6 2 1 0 2 2 2 1 Stathmin family IPK PF03770.16 OWF54400.1 - 0.59 10.0 10.6 0.052 13.4 5.1 1.9 2 0 0 2 2 2 0 Inositol polyphosphate kinase Exonuc_VII_L PF02601.15 OWF54400.1 - 1.9 8.0 13.0 0.35 10.4 9.4 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phasin PF05597.11 OWF54400.1 - 2.6 8.1 16.3 2.8 8.0 14.6 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MAT1 PF06391.13 OWF54400.1 - 2.8 7.7 30.3 3.7 7.3 22.5 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Ribosomal_S30AE PF02482.19 OWF54400.1 - 2.9 8.8 15.9 4.3 8.2 14.9 1.9 1 1 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Syntaxin_2 PF14523.6 OWF54401.1 - 3.6e-30 104.3 13.2 4.3e-29 100.9 8.3 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 OWF54401.1 - 1.1e-20 73.3 0.6 1.1e-20 73.3 0.6 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 OWF54401.1 - 2.1e-11 43.9 16.4 8.4e-11 41.9 16.4 1.9 1 1 0 1 1 1 1 Syntaxin DNA_repr_REX1B PF14966.6 OWF54401.1 - 0.0029 18.2 0.1 0.0029 18.2 0.1 2.8 2 2 2 4 4 4 1 DNA repair REX1-B AAA_13 PF13166.6 OWF54401.1 - 0.021 13.5 11.2 0.032 12.9 11.2 1.3 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 OWF54401.1 - 0.051 13.8 19.1 0.038 14.2 7.2 3.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2207 PF09972.9 OWF54401.1 - 0.059 12.1 0.4 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DASH_Dad4 PF08650.10 OWF54401.1 - 0.069 13.1 3.8 0.14 12.1 0.9 2.7 2 1 1 3 3 3 0 DASH complex subunit Dad4 MCPsignal PF00015.21 OWF54401.1 - 0.12 12.2 9.6 3 7.6 1.2 2.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4988 PF16378.5 OWF54401.1 - 0.12 12.0 2.6 0.51 10.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function Prominin PF05478.11 OWF54401.1 - 0.14 10.1 15.1 0.0067 14.5 1.4 2.1 1 1 0 2 2 2 0 Prominin DUF3040 PF11239.8 OWF54401.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Herpes_US9 PF06072.11 OWF54401.1 - 0.19 11.6 0.3 0.38 10.7 0.3 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ETRAMP PF09716.10 OWF54401.1 - 0.29 11.2 1.1 0.44 10.6 1.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GAS PF13851.6 OWF54401.1 - 0.31 10.3 16.9 0.044 13.1 6.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2730 PF10805.8 OWF54401.1 - 0.49 10.5 4.4 0.2 11.8 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Phage_GP20 PF06810.11 OWF54401.1 - 0.78 9.5 9.7 0.67 9.7 1.4 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 HTH_WhiA PF02650.14 OWF54401.1 - 1.5 9.2 7.0 0.24 11.8 1.8 2.3 2 2 0 2 2 2 0 WhiA C-terminal HTH domain FUSC PF04632.12 OWF54401.1 - 1.5 7.2 6.7 0.78 8.2 4.7 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 OWF54401.1 - 2.8 7.1 12.9 3.8 6.7 1.7 2.9 1 1 2 3 3 3 0 TMPIT-like protein Synaptobrevin PF00957.21 OWF54401.1 - 4 7.3 9.7 0.35 10.7 3.4 2.4 2 1 0 2 2 2 0 Synaptobrevin NPV_P10 PF05531.12 OWF54401.1 - 4.8 7.7 12.4 0.28 11.7 1.6 2.7 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OWF54401.1 - 8.4 6.4 13.1 5 7.2 1.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.32 OWF54402.1 - 6.1e-12 45.9 1.8 0.0021 18.9 0.3 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF54402.1 - 0.0093 16.2 0.0 5.5 7.4 0.0 3.5 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain FRG2 PF15315.6 OWF54402.1 - 0.18 12.0 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 LRR_4 PF12799.7 OWF54404.1 - 2.3e-18 66.0 10.2 4.3e-06 27.0 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF54404.1 - 1.3e-14 54.1 3.3 3.7e-07 29.8 0.0 3.7 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 OWF54404.1 - 1.3e-13 50.4 13.1 1.2e-07 31.4 1.7 4.0 3 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 OWF54404.1 - 0.00042 20.5 13.4 16 6.6 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 OWF54404.1 - 1.5 9.1 14.0 21 5.5 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich repeat Nkap_C PF06047.11 OWF54406.1 - 0.17 12.0 0.1 0.42 10.8 0.1 1.6 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain Cwf_Cwc_15 PF04889.12 OWF54407.1 - 3 7.5 8.2 0.084 12.6 1.5 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peroxin-13_N PF04088.13 OWF54408.1 - 7.9e-47 159.2 0.5 1.1e-46 158.7 0.5 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 OWF54408.1 - 4.1e-08 33.0 0.0 8.4e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF54408.1 - 6.7e-07 28.9 0.1 1.7e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OWF54408.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain BC10 PF06726.12 OWF54409.1 - 1.1e-24 86.4 8.5 1.5e-24 86.0 8.5 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Radical_SAM_C PF16199.5 OWF54410.1 - 1.9e-33 114.3 0.0 4.5e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OWF54410.1 - 8.5e-22 78.3 0.5 3.7e-20 73.0 0.0 3.3 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OWF54410.1 - 3.8e-10 40.0 0.1 6.5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF54410.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF54410.1 - 0.025 15.0 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SWIM PF04434.17 OWF54411.1 - 0.0067 16.1 1.1 0.015 15.0 1.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger RNA_pol_Rpb5_N PF03871.14 OWF54412.1 - 4.7e-35 120.0 0.1 7.5e-35 119.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 OWF54412.1 - 5.3e-33 112.7 0.2 1e-32 111.8 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain GSHPx PF00255.19 OWF54413.1 - 6.5e-13 48.2 0.0 1.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_8 PF13905.6 OWF54414.1 - 5.1e-30 103.7 0.0 1.2e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OWF54414.1 - 8.3e-10 38.6 0.1 1.3e-06 28.3 0.0 2.6 1 1 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 OWF54414.1 - 1.6e-07 31.3 0.0 3.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OWF54414.1 - 1.4e-06 28.1 0.2 2.8e-05 23.9 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin TraF PF13728.6 OWF54414.1 - 4.3e-06 26.7 0.8 4.2e-05 23.5 0.0 2.5 1 1 1 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 OWF54414.1 - 1.1e-05 25.1 0.2 2.8e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Redoxin Thioredoxin_2 PF13098.6 OWF54414.1 - 6.6e-05 23.3 0.4 0.00016 22.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain GIT_SHD PF08518.11 OWF54414.1 - 0.036 13.7 0.3 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT Glutaredoxin PF00462.24 OWF54414.1 - 0.12 12.7 1.3 3 8.1 0.1 2.8 2 1 0 2 2 2 0 Glutaredoxin DNA_ligase_A_M PF01068.21 OWF54416.1 - 4.1e-47 160.5 0.1 9.4e-47 159.3 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OWF54416.1 - 1.9e-42 145.5 0.3 1.9e-42 145.5 0.3 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OWF54416.1 - 1.9e-19 70.1 0.0 5.9e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 OWF54416.1 - 3.1e-14 53.1 0.0 1.4e-06 28.6 0.0 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OWF54416.1 - 2.9e-11 43.6 0.0 5.7e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 OWF54416.1 - 1e-09 38.4 0.2 2.1e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.19 OWF54416.1 - 6e-06 26.2 0.4 8.5e-05 22.5 0.4 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Peptidase_M48 PF01435.18 OWF54417.1 - 4.3e-29 101.7 0.2 5.5e-29 101.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_U49 PF10463.9 OWF54417.1 - 0.004 16.9 0.2 0.83 9.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase U49 SprT-like PF10263.9 OWF54417.1 - 0.049 13.5 0.7 0.097 12.5 0.7 1.4 1 0 0 1 1 1 0 SprT-like family DUF2268 PF10026.9 OWF54417.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Phage_holin_2_1 PF04971.12 OWF54418.1 - 5.9e-05 23.0 13.6 70 3.5 0.0 10.3 3 2 10 13 13 13 3 Bacteriophage P21 holin S Ank_2 PF12796.7 OWF54419.1 - 6.3e-25 87.6 2.8 7.6e-12 45.7 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF54419.1 - 8.2e-20 68.8 0.3 0.0013 19.1 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF54419.1 - 1.6e-19 69.7 1.0 1.8e-06 28.1 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF54419.1 - 2.2e-17 63.2 0.2 0.00022 21.7 0.0 4.7 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF54419.1 - 6.3e-15 54.9 0.4 0.0018 18.6 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ion_trans PF00520.31 OWF54419.1 - 2.7e-12 46.4 17.6 6.5e-12 45.2 17.6 1.6 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OWF54419.1 - 5e-06 25.5 7.5 5e-06 25.5 7.5 3.1 2 1 1 3 3 3 2 Polycystin cation channel SKA2 PF16740.5 OWF54419.1 - 0.093 12.5 0.6 0.4 10.5 0.6 2.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Arf PF00025.21 OWF54421.1 - 1.5e-46 158.0 0.3 2e-46 157.6 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF54421.1 - 1.9e-13 50.7 0.1 2.6e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF54421.1 - 7.6e-13 48.4 0.0 9.2e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OWF54421.1 - 5.7e-11 42.2 0.6 1.5e-07 30.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF54421.1 - 6e-08 32.8 0.1 8.2e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF54421.1 - 6.5e-07 28.9 0.1 7.9e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OWF54421.1 - 3.7e-05 23.2 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF2689 PF10894.8 OWF54421.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) NUDIX PF00293.28 OWF54423.1 - 1.2e-16 61.0 0.3 1.4e-16 60.8 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain Tcp10_C PF07202.13 OWF54424.1 - 2.4 8.1 11.4 6.7 6.6 0.7 4.3 1 1 0 2 2 2 0 T-complex protein 10 C-terminus Peptidase_A22B PF04258.13 OWF54425.1 - 1.2e-99 333.4 10.3 1.6e-99 333.0 10.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OWF54425.1 - 0.0003 20.4 10.6 0.0003 20.4 10.6 2.0 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 OWF54425.1 - 0.0017 17.2 4.1 0.0017 17.2 4.1 2.0 1 1 0 2 2 2 1 Presenilin DUF4345 PF14248.6 OWF54425.1 - 0.057 13.3 0.3 0.057 13.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4345) DUF5058 PF16481.5 OWF54425.1 - 0.065 12.9 4.5 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5058) MASE5 PF17178.4 OWF54425.1 - 0.2 11.5 0.1 0.2 11.5 0.1 2.8 2 1 1 3 3 3 0 Membrane-associated sensor Tetraspanin PF00335.20 OWF54425.1 - 1.6 8.4 5.9 1.4 8.5 0.5 2.6 2 1 0 2 2 2 0 Tetraspanin family Forkhead PF00250.18 OWF54426.1 - 9.5e-37 125.1 0.0 1.7e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain CDC45 PF02724.14 OWF54426.1 - 0.19 10.0 1.4 0.22 9.8 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OWF54426.1 - 6.3 6.1 10.7 9.1 5.6 10.7 1.2 1 0 0 1 1 1 0 SDA1 DUF668 PF05003.12 OWF54428.1 - 0.034 14.6 0.1 16 6.0 0.0 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF668) DUF3910 PF13049.6 OWF54428.1 - 0.12 12.7 1.7 11 6.4 0.2 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3910) CH PF00307.31 OWF54428.1 - 0.15 12.3 0.1 40 4.4 0.0 3.3 1 1 2 3 3 3 0 Calponin homology (CH) domain FUSC PF04632.12 OWF54428.1 - 0.78 8.2 3.4 1 7.8 3.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF417 PF04224.12 OWF54429.1 - 7 6.2 7.5 1.1e+03 -1.0 7.5 3.3 1 1 0 1 1 1 0 Protein of unknown function, DUF417 DUF3552 PF12072.8 OWF54430.1 - 0.039 13.4 21.0 0.016 14.6 13.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) OEP PF02321.18 OWF54430.1 - 0.13 12.1 18.2 0.14 11.9 6.6 2.0 1 1 1 2 2 2 0 Outer membrane efflux protein PIF1 PF05970.14 OWF54431.1 - 0.1 11.7 0.3 0.19 10.8 0.3 1.4 1 0 0 1 1 1 0 PIF1-like helicase FliD_C PF07195.12 OWF54431.1 - 0.84 9.0 5.7 0.43 10.0 0.7 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Ank_2 PF12796.7 OWF54432.1 - 7.9e-44 148.1 2.6 1.4e-13 51.2 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF54432.1 - 2.9e-26 91.5 4.4 6.2e-10 39.4 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF54432.1 - 6.8e-24 81.3 0.9 4.7e-05 23.5 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 OWF54432.1 - 1.7e-22 78.8 1.3 0.0027 18.1 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OWF54432.1 - 2.3e-16 59.6 13.0 1.7e-06 28.2 0.2 5.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) DUF249 PF03158.13 OWF54432.1 - 0.00066 19.4 0.0 0.0015 18.3 0.0 1.5 2 0 0 2 2 2 1 Multigene family 530 protein Neur_chan_LBD PF02931.23 OWF54433.1 - 5.1e-24 84.9 0.5 5.6e-24 84.8 0.5 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF54434.1 - 8.6e-18 65.3 8.2 3.3e-15 56.8 3.5 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ni_hydr_CYTB PF01292.20 OWF54434.1 - 0.071 12.7 0.0 0.82 9.2 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF2663 PF10864.8 OWF54434.1 - 0.1 13.0 0.8 0.2 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) DUF3397 PF11877.8 OWF54434.1 - 0.19 12.0 11.0 0.02 15.1 5.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) Sid-5 PF17204.3 OWF54434.1 - 0.63 10.3 2.5 0.52 10.5 0.2 2.1 2 0 0 2 2 2 0 Sid-5 family Filamin PF00630.19 OWF54435.1 - 0.008 17.0 0.0 0.018 15.9 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Neurexophilin PF06312.12 OWF54435.1 - 0.008 15.7 0.2 0.037 13.5 0.2 2.0 1 1 0 1 1 1 1 Neurexophilin Invasin_D3 PF09134.10 OWF54435.1 - 0.019 15.3 0.1 0.046 14.0 0.1 1.5 1 0 0 1 1 1 0 Invasin, domain 3 ACT PF01842.25 OWF54435.1 - 0.17 11.7 0.0 0.6 9.9 0.1 2.0 2 0 0 2 2 2 0 ACT domain Pkinase PF00069.25 OWF54436.1 - 2.9e-23 82.6 0.0 1.4e-22 80.3 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF54436.1 - 2.6e-15 56.4 0.0 4.7e-14 52.3 0.0 2.3 1 1 1 2 2 2 1 Protein tyrosine kinase Taq-exonuc PF09281.10 OWF54436.1 - 0.047 13.7 0.1 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 Taq polymerase, exonuclease Cation_efflux PF01545.21 OWF54437.1 - 3.8e-50 170.4 8.5 4.6e-50 170.1 8.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3040 PF11239.8 OWF54437.1 - 0.29 11.4 2.0 0.6 10.4 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) NAD_kinase PF01513.21 OWF54438.1 - 2.1e-12 46.9 0.0 3.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 ATP-NAD kinase Peptidase_S51 PF03575.17 OWF54438.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 DAGK_cat PF00781.24 OWF54438.1 - 0.066 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Vasculin PF15337.6 OWF54439.1 - 8.9e-12 45.7 4.9 8.9e-12 45.7 4.9 1.8 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 Band_3_cyto PF07565.13 OWF54439.1 - 2.1 8.1 6.0 0.41 10.4 0.3 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain zf-B_box PF00643.24 OWF54441.1 - 4.2e-10 39.6 30.8 2.6e-08 33.9 10.2 3.7 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF54441.1 - 7.6e-07 28.9 8.9 7.6e-07 28.9 8.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF54441.1 - 6.5e-06 25.9 6.2 6.5e-06 25.9 6.2 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF54441.1 - 6.9e-06 26.0 9.1 6.9e-06 26.0 9.1 3.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF54441.1 - 0.00015 21.9 11.4 0.00015 21.9 11.4 4.2 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF54441.1 - 0.00082 19.2 8.9 0.00082 19.2 8.9 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54441.1 - 0.00087 19.2 6.8 0.00087 19.2 6.8 4.1 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF54441.1 - 0.001 19.4 9.0 0.001 19.4 9.0 3.8 3 0 0 3 3 3 2 Ring finger domain NHL PF01436.21 OWF54441.1 - 0.11 12.6 4.0 28 5.0 0.1 4.5 4 0 0 4 4 4 0 NHL repeat zf-B_box PF00643.24 OWF54442.1 - 3.5e-10 39.8 4.3 3.5e-10 39.8 4.3 3.8 3 1 0 3 3 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 OWF54442.1 - 2.4e-06 27.5 9.4 2.4e-06 27.5 9.4 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF54442.1 - 1.2e-05 25.0 12.4 1.2e-05 25.0 12.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF54442.1 - 2.6e-05 24.3 11.1 2.6e-05 24.3 11.1 3.3 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF54442.1 - 0.00022 21.0 10.1 0.00022 21.0 10.1 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF54442.1 - 0.0019 18.0 11.6 0.0019 18.0 11.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54442.1 - 0.0029 17.5 11.8 0.0029 17.5 11.8 4.0 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF54442.1 - 0.015 15.6 10.9 0.015 15.6 10.9 3.5 3 0 0 3 3 3 0 Ring finger domain PGM_PMM_I PF02878.16 OWF54443.1 - 1.7e-33 115.3 0.1 2.7e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OWF54443.1 - 4.2e-31 107.5 0.0 7.7e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OWF54443.1 - 4.9e-12 46.4 0.0 1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OWF54443.1 - 3.8e-07 30.2 0.0 8.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.25 OWF54444.1 - 1.9e-68 230.7 0.0 2.4e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF54444.1 - 1.7e-30 106.1 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF54444.1 - 2.1e-05 24.5 0.1 0.042 13.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF54444.1 - 3e-05 23.1 0.0 4.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OWF54444.1 - 4.3e-05 22.5 0.0 6.8e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OWF54444.1 - 0.00014 21.3 0.5 0.00035 20.0 0.2 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3245 PF11595.8 OWF54444.1 - 0.063 13.8 0.3 0.49 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Kinase-like PF14531.6 OWF54444.1 - 0.13 11.6 0.0 0.57 9.5 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Surp PF01805.20 OWF54445.1 - 1.1e-18 67.0 4.7 1.1e-16 60.6 0.9 2.7 2 0 0 2 2 2 2 Surp module CTD_bind PF04818.13 OWF54445.1 - 6.5e-17 62.1 1.1 6.5e-17 62.1 1.1 2.9 3 1 0 3 3 3 1 RNA polymerase II-binding domain. G-patch PF01585.23 OWF54445.1 - 4.1e-12 45.8 3.3 9.2e-12 44.7 3.3 1.6 1 0 0 1 1 1 1 G-patch domain Spt20 PF12090.8 OWF54445.1 - 0.0061 16.2 10.4 0.0061 16.2 10.4 4.1 4 1 0 4 4 4 1 Spt20 family ATP-synt_D PF01813.17 OWF54445.1 - 0.2 11.4 6.7 0.45 10.3 2.3 2.3 2 0 0 2 2 2 0 ATP synthase subunit D FliD_C PF07195.12 OWF54445.1 - 0.22 10.9 14.4 0.14 11.5 0.6 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spore_III_AB PF09548.10 OWF54445.1 - 1.5 8.9 11.0 4.2 7.4 1.2 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) ENTH PF01417.20 OWF54445.1 - 2.8 8.0 7.1 12 5.9 0.8 2.7 2 0 0 2 2 2 0 ENTH domain MCU PF04678.13 OWF54445.1 - 3.5 7.7 21.6 0.41 10.7 4.5 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter ABC2_membrane_3 PF12698.7 OWF54445.1 - 5.6 6.0 12.3 2 7.4 0.8 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Tctex-1 PF03645.13 OWF54446.1 - 1.9e-19 69.8 0.4 2.7e-19 69.3 0.4 1.2 1 0 0 1 1 1 1 Tctex-1 family Cobalamin_bind PF01122.19 OWF54447.1 - 5.4e-17 61.7 3.0 8.1e-17 61.1 3.0 1.2 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein Phage_holin_5_2 PF16079.5 OWF54447.1 - 0.024 15.0 2.5 0.84 10.0 0.2 2.9 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF4430 PF14478.6 OWF54447.1 - 0.028 15.0 0.0 0.061 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) mIF3 PF14877.6 OWF54447.1 - 0.27 10.9 1.8 0.42 10.3 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial translation initiation factor Cyclase PF04199.13 OWF54448.1 - 2.8e-32 111.8 0.1 5.5e-32 110.9 0.2 1.4 2 0 0 2 2 2 1 Putative cyclase Cyclase PF04199.13 OWF54449.1 - 6.8e-05 23.1 0.0 8.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Ank_2 PF12796.7 OWF54450.1 - 1.2e-39 134.8 21.2 4.2e-14 52.9 1.1 5.6 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 OWF54450.1 - 1.3e-36 123.4 4.8 9.8e-08 32.1 0.2 7.8 7 0 0 7 7 7 5 Ankyrin repeat MIB_HERC2 PF06701.13 OWF54450.1 - 2.2e-36 123.9 13.3 1.6e-19 69.9 1.4 3.4 3 0 0 3 3 3 2 Mib_herc2 Ank_5 PF13857.6 OWF54450.1 - 2.8e-32 110.4 6.4 7.1e-09 35.8 0.0 6.2 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF54450.1 - 7e-31 106.2 5.3 2.3e-07 31.2 0.1 7.2 3 1 4 7 7 7 6 Ankyrin repeats (many copies) PARP PF00644.20 OWF54450.1 - 1e-24 87.2 0.1 2.2e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SH3_15 PF18346.1 OWF54450.1 - 2e-23 82.5 9.2 3.8e-16 59.2 1.5 3.2 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain Ank_3 PF13606.6 OWF54450.1 - 4.3e-22 75.8 2.5 0.0051 17.2 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat ZZ PF00569.17 OWF54450.1 - 2.9e-10 39.8 4.4 6.1e-10 38.7 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Ank_2 PF12796.7 OWF54451.1 - 2.2e-37 127.5 14.1 6.2e-13 49.2 0.4 5.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF54451.1 - 2.8e-37 126.3 7.2 9.9e-10 38.5 0.3 6.7 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF54451.1 - 4.7e-37 124.8 9.3 6.9e-08 32.6 0.4 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 OWF54451.1 - 5.6e-34 116.1 5.7 4.4e-07 30.3 0.5 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) MIB_HERC2 PF06701.13 OWF54451.1 - 1.8e-32 111.3 28.3 3.5e-17 62.4 5.2 4.1 4 0 0 4 4 4 2 Mib_herc2 PARP PF00644.20 OWF54451.1 - 1.9e-26 92.9 0.0 4.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank_3 PF13606.6 OWF54451.1 - 3.5e-25 85.3 2.1 0.00013 22.1 0.1 8.5 8 0 0 8 8 8 5 Ankyrin repeat SH3_15 PF18346.1 OWF54451.1 - 7.8e-25 87.0 3.6 2.6e-14 53.3 0.3 2.9 2 0 0 2 2 2 2 Mind bomb SH3 repeat domain ZZ PF00569.17 OWF54451.1 - 1.1e-07 31.5 5.0 2.6e-07 30.3 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type ATP-synt_DE_N PF02823.16 OWF54451.1 - 0.028 14.3 0.1 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain TPR_20 PF14561.6 OWF54451.1 - 0.51 10.7 2.6 2 8.8 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1702 PF08012.11 OWF54452.1 - 1e-09 37.8 0.0 12 4.7 0.0 8.3 2 1 12 14 14 14 12 Protein of unknown function (DUF1702) EMP24_GP25L PF01105.24 OWF54453.1 - 0.034 14.1 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Gp138_N PF18352.1 OWF54454.1 - 7.6e-09 35.5 2.7 18 5.5 0.0 7.6 2 1 12 14 14 14 12 Phage protein Gp138 N-terminal domain DUF2407_C PF13373.6 OWF54455.1 - 0.12 12.6 0.2 0.17 12.1 0.2 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain Asp_protease PF09668.10 OWF54456.1 - 8.4e-59 196.8 0.6 1.3e-58 196.2 0.6 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OWF54456.1 - 4.5e-25 88.0 0.0 2.2e-24 85.8 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 OWF54456.1 - 2.9e-10 39.8 0.0 6.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 OWF54456.1 - 7e-09 36.2 0.0 4.1e-08 33.8 0.0 2.4 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.20 OWF54456.1 - 2.5e-05 24.5 0.1 0.00013 22.2 0.1 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease UBA PF00627.31 OWF54456.1 - 3.2e-05 23.7 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 OWF54456.1 - 0.00029 20.6 0.1 0.0006 19.6 0.1 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease MAJIN PF15077.6 OWF54457.1 - 3.8e-05 23.6 4.4 3.8e-05 23.6 4.4 4.0 2 2 1 4 4 4 1 Membrane-anchored junction protein CCDC50_N PF15295.6 OWF54459.1 - 1.2e-28 99.8 50.0 1.3e-27 96.4 16.2 3.2 3 1 0 3 3 3 2 Coiled-coil domain-containing protein 50 N-terminus PhnA_Zn_Ribbon PF08274.12 OWF54460.1 - 0.075 13.0 1.5 0.09 12.7 0.0 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon OrfB_Zn_ribbon PF07282.11 OWF54460.1 - 0.23 11.4 3.1 0.21 11.6 1.8 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.12 OWF54460.1 - 0.5 10.7 5.4 0.92 9.8 5.4 1.4 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Amino_oxidase PF01593.24 OWF54461.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Ald_Xan_dh_C2 PF02738.18 OWF54462.1 - 3.5e-177 590.2 0.0 4.9e-177 589.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OWF54462.1 - 1.1e-37 129.4 0.0 1.9e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 OWF54462.1 - 1.7e-28 99.2 0.0 3.2e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OWF54462.1 - 7.3e-27 93.2 0.3 2.3e-26 91.6 0.3 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OWF54462.1 - 9.2e-16 57.9 0.0 3.8e-15 55.9 0.0 2.2 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OWF54462.1 - 2e-08 34.1 0.3 7.1e-08 32.3 0.3 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Galactosyl_T PF01762.21 OWF54463.1 - 1.4e-46 158.8 0.0 1.8e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF54463.1 - 0.00053 19.5 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 Fringe-like C1q PF00386.21 OWF54464.1 - 1.5e-15 57.5 0.1 2.6e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 C1q domain SlyX PF04102.12 OWF54464.1 - 0.0022 18.6 2.0 0.0046 17.6 2.0 1.6 1 0 0 1 1 1 1 SlyX Spc29 PF17082.5 OWF54464.1 - 0.0024 17.7 1.8 0.0035 17.2 1.8 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 BclA_C PF18573.1 OWF54464.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 BclA C-terminal domain CBM_35 PF16990.5 OWF54464.1 - 0.021 15.1 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) PreAtp-grasp PF18604.1 OWF54464.1 - 0.022 14.4 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Pre ATP-grasp domain FliD_N PF02465.18 OWF54464.1 - 0.023 15.4 2.1 0.045 14.5 2.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF848 PF05852.11 OWF54464.1 - 0.023 14.8 1.4 0.035 14.2 1.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PKcGMP_CC PF16808.5 OWF54464.1 - 0.031 14.1 1.7 0.05 13.5 1.7 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 OWF54464.1 - 0.082 13.2 0.6 0.14 12.5 0.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Prefoldin PF02996.17 OWF54465.1 - 0.13 12.2 2.1 5.8 6.9 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit MAM PF00629.23 OWF54467.1 - 9.1e-28 97.2 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Sushi PF00084.20 OWF54467.1 - 0.0006 20.3 0.1 0.0018 18.8 0.1 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) HRM PF02793.22 OWF54467.1 - 0.051 13.9 0.3 0.051 13.9 0.3 2.3 2 0 0 2 2 2 0 Hormone receptor domain Glypican PF01153.19 OWF54468.1 - 4.3e-88 296.5 0.5 6.4e-88 296.0 0.5 1.2 1 0 0 1 1 1 1 Glypican Fz PF01392.22 OWF54468.1 - 0.0069 17.0 1.0 0.02 15.5 1.0 1.8 1 0 0 1 1 1 1 Fz domain RecR PF02132.15 OWF54468.1 - 0.15 11.7 0.8 0.49 10.0 0.8 1.9 1 0 0 1 1 1 0 RecR protein Hrs_helical PF12210.8 OWF54468.1 - 0.16 12.5 0.6 0.42 11.2 0.1 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MCM PF00493.23 OWF54469.1 - 4.6e-102 339.9 0.0 8.5e-102 339.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OWF54469.1 - 4.5e-35 120.3 0.5 9.4e-35 119.2 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 OWF54469.1 - 8.3e-24 84.2 0.5 2.4e-23 82.7 0.5 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 OWF54469.1 - 3.5e-23 81.8 1.0 8.5e-23 80.6 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OWF54469.1 - 3.9e-08 32.9 0.5 1.1e-05 24.9 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF54469.1 - 1.4e-06 28.3 0.0 4.3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_bind PF09739.9 OWF54469.1 - 0.0085 14.6 0.1 0.015 13.8 0.1 1.3 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor AAA_lid_2 PF17863.1 OWF54469.1 - 0.011 15.6 2.0 0.032 14.1 0.7 2.4 2 0 0 2 2 2 0 AAA lid domain Sigma54_activat PF00158.26 OWF54469.1 - 0.044 13.5 0.0 0.17 11.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 OWF54469.1 - 0.14 12.9 0.9 0.52 11.0 0.9 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Cullin_binding PF03556.15 OWF54470.1 - 1.4e-38 132.0 3.4 1.8e-38 131.7 0.9 2.1 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 OWF54470.1 - 2.9e-10 39.8 0.2 1.9e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 UBA-like domain Thymidylat_synt PF00303.19 OWF54470.1 - 0.07 12.2 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase LRR_6 PF13516.6 OWF54471.1 - 7.6e-08 31.8 5.2 0.08 13.0 0.1 4.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 OWF54471.1 - 0.041 14.3 0.3 1.4 9.4 0.1 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) PIEZO PF15917.5 OWF54471.1 - 0.075 12.5 1.0 0.24 10.8 1.0 1.8 1 0 0 1 1 1 0 Piezo TPR_2 PF07719.17 OWF54472.1 - 2.2e-17 61.7 7.0 0.0038 17.2 0.1 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OWF54472.1 - 2.6e-17 61.8 8.3 0.0016 18.2 0.1 6.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF54472.1 - 3.6e-12 46.0 0.2 0.0032 18.1 0.1 5.0 2 2 3 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OWF54472.1 - 1.1e-10 40.8 2.7 0.036 14.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF54472.1 - 9e-10 39.0 0.1 0.0018 18.9 0.0 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF54472.1 - 5.6e-09 36.0 0.9 0.0004 20.5 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF54472.1 - 1.5e-08 35.0 3.1 0.03 14.8 0.1 4.8 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF54472.1 - 2.8e-06 27.5 3.1 0.47 10.8 0.0 4.9 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF54472.1 - 2.9e-06 27.3 1.8 0.28 11.6 0.0 5.8 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF54472.1 - 7.5e-06 25.5 1.0 0.01 15.5 0.1 3.8 3 1 1 4 4 4 2 TPR repeat TPR_21 PF09976.9 OWF54472.1 - 0.0007 19.4 0.0 0.089 12.5 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 OWF54472.1 - 0.00095 19.7 9.3 5.2 7.9 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF54472.1 - 0.0016 18.4 0.1 6.9 6.8 0.1 4.7 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 OWF54472.1 - 0.0081 15.4 0.1 17 4.5 0.0 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF54472.1 - 0.37 11.0 9.6 4.5 7.6 0.0 4.2 2 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-B_box PF00643.24 OWF54473.1 - 0.0095 16.1 11.7 0.019 15.1 11.7 1.5 1 0 0 1 1 1 1 B-box zinc finger LMBR1 PF04791.16 OWF54473.1 - 0.3 10.0 0.9 0.37 9.7 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PhoLip_ATPase_C PF16212.5 OWF54474.1 - 4.2e-66 223.3 31.8 4.2e-66 223.3 31.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OWF54474.1 - 5.8e-22 77.2 1.1 5.8e-22 77.2 1.1 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OWF54474.1 - 1.8e-13 51.3 0.4 9.4e-08 32.6 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OWF54474.1 - 2.7e-10 40.2 0.0 1.5e-08 34.6 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OWF54474.1 - 6.7e-10 38.8 1.1 5.9e-09 35.7 1.1 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OWF54474.1 - 0.0017 18.2 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3052 PF11253.8 OWF54474.1 - 0.0032 17.4 0.1 0.0088 16.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) Ldl_recept_b PF00058.17 OWF54475.1 - 0.042 14.3 0.5 18 5.9 0.0 3.3 2 2 1 3 3 3 0 Low-density lipoprotein receptor repeat class B Lip_prot_lig_C PF10437.9 OWF54475.1 - 0.14 12.2 0.0 4.2 7.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus DUF1412 PF07203.11 OWF54475.1 - 0.36 11.1 7.0 9.1 6.6 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1412) FYVE PF01363.21 OWF54476.1 - 0.0099 16.0 1.1 0.029 14.5 0.0 2.0 2 0 0 2 2 2 1 FYVE zinc finger zf-C2HC_2 PF13913.6 OWF54476.1 - 3.8 7.5 7.5 0.18 11.8 1.5 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PID_2 PF14719.6 OWF54478.1 - 3.1e-22 79.3 0.5 4.1e-22 78.9 0.5 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 OWF54478.1 - 4.4e-09 36.5 0.8 7.1e-08 32.6 0.8 2.4 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF4718 PF15842.5 OWF54478.1 - 0.079 12.7 2.2 0.12 12.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF2681 PF10883.8 OWF54478.1 - 0.13 12.6 2.0 0.24 11.8 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) AWS PF17907.1 OWF54478.1 - 1.8 8.6 8.0 11 6.1 0.0 3.1 2 1 1 3 3 3 0 AWS domain PID_2 PF14719.6 OWF54479.1 - 8.6e-22 77.9 0.4 1.1e-21 77.5 0.4 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 OWF54479.1 - 7.4e-09 35.8 0.8 1.1e-07 32.0 0.8 2.4 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF4718 PF15842.5 OWF54479.1 - 0.065 13.0 2.4 0.096 12.5 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF2681 PF10883.8 OWF54479.1 - 0.16 12.4 2.2 0.27 11.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) AWS PF17907.1 OWF54479.1 - 5.9 7.0 7.8 11 6.1 0.0 3.1 2 1 1 3 3 3 0 AWS domain Ras PF00071.22 OWF54480.1 - 2.3e-53 180.1 0.0 2.6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF54480.1 - 3e-21 75.9 0.0 4.5e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF54480.1 - 8.1e-09 35.2 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family adh_short_C2 PF13561.6 OWF54481.1 - 8.1e-50 169.6 0.3 1.1e-49 169.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF54481.1 - 6.9e-48 162.7 0.1 8.6e-48 162.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF54481.1 - 1.7e-09 37.9 0.1 2.7e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 KR domain PQ-loop PF04193.14 OWF54482.1 - 1.1e-20 73.2 10.6 8.1e-15 54.3 1.3 3.0 2 1 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 OWF54482.1 - 0.00042 20.3 4.9 0.00068 19.6 2.2 2.4 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange SSF PF00474.17 OWF54483.1 - 9.9e-45 153.1 22.5 1.7e-44 152.4 22.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF997 PF06196.12 OWF54483.1 - 4.5 7.3 12.7 2.5 8.2 4.5 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF997) PALP PF00291.25 OWF54484.1 - 2.2e-33 116.0 0.0 2.5e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 OWF54485.1 - 4.1e-47 160.8 0.1 4.8e-47 160.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF54485.1 - 2.7e-32 112.1 0.0 3.1e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF54485.1 - 0.0069 15.2 0.0 0.06 12.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OWF54485.1 - 0.014 14.4 1.9 0.055 12.4 1.9 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OWF54485.1 - 0.045 13.1 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OWF54485.1 - 0.081 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF54485.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mid2 PF04478.12 OWF54486.1 - 0.002 17.9 0.4 0.0042 16.9 0.4 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.20 OWF54486.1 - 0.0056 16.6 0.6 0.014 15.3 0.6 1.6 1 0 0 1 1 1 1 Syndecan domain DUF485 PF04341.12 OWF54486.1 - 0.091 12.7 0.3 0.36 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 EphA2_TM PF14575.6 OWF54486.1 - 0.094 13.6 1.1 0.14 13.0 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OWF54486.1 - 0.15 12.8 1.6 1.7 9.4 0.1 2.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 OWF54486.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Baculo_11_kDa PF06143.11 OWF54486.1 - 0.19 11.3 0.3 0.42 10.2 0.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family SKG6 PF08693.10 OWF54486.1 - 7.1 6.1 7.6 14 5.2 7.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FH2 PF02181.23 OWF54487.1 - 1.6e-79 267.7 5.9 3.3e-79 266.7 5.9 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OWF54487.1 - 1.9e-26 92.9 1.1 1.9e-26 92.9 1.1 2.5 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OWF54487.1 - 2.7e-15 56.4 0.8 8.3e-15 54.8 0.8 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Laminin_II PF06009.12 OWF54487.1 - 0.0026 17.8 0.2 0.011 15.8 0.2 2.1 1 0 0 1 1 1 1 Laminin Domain II DUF3361 PF11841.8 OWF54487.1 - 0.055 13.4 0.3 0.28 11.1 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) PRP9_N PF16958.5 OWF54487.1 - 2.6 8.1 20.1 7 6.7 0.5 4.5 3 1 1 4 4 4 0 Pre-mRNA-splicing factor PRP9 N-terminus Peroxin-13_N PF04088.13 OWF54487.1 - 3.2 8.0 5.0 6.9 6.9 0.5 2.6 2 0 0 2 2 2 0 Peroxin 13, N-terminal region YabA PF06156.13 OWF54488.1 - 0.014 16.0 1.7 0.34 11.6 2.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Chibby PF14645.6 OWF54488.1 - 0.017 15.5 1.2 0.05 14.0 1.2 1.7 1 0 0 1 1 1 0 Chibby family Nmad5 PF18757.1 OWF54488.1 - 0.023 14.9 0.4 0.037 14.2 0.4 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 Ribosomal_L22 PF00237.19 OWF54488.1 - 0.026 14.7 0.1 0.089 13.0 0.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e FOXP-CC PF16159.5 OWF54488.1 - 0.089 13.4 0.6 0.089 13.4 0.6 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain Mod_r PF07200.13 OWF54488.1 - 0.86 9.7 10.3 0.21 11.7 4.1 2.6 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.15 OWF54488.1 - 3.2 7.6 7.2 8.2 6.3 7.2 1.7 1 0 0 1 1 1 0 Septum formation initiator NHL PF01436.21 OWF54489.1 - 6.2e-47 155.3 22.4 2.2e-09 36.9 0.1 6.6 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 OWF54489.1 - 1.6e-14 53.8 7.3 2.8e-06 26.7 0.1 5.1 2 1 3 5 5 5 4 6-bladed beta-propeller Filamin PF00630.19 OWF54489.1 - 2.2e-14 54.1 0.1 8.7e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Filamin/ABP280 repeat SGL PF08450.12 OWF54489.1 - 7.8e-12 45.3 1.7 0.0002 21.0 0.0 4.4 1 1 2 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 OWF54489.1 - 2e-09 37.3 5.7 2e-09 37.3 5.7 3.6 1 1 1 2 2 1 1 RING-type zinc-finger zf-B_box PF00643.24 OWF54489.1 - 1.1e-08 35.1 6.8 1.1e-08 35.1 6.8 3.8 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF54489.1 - 1.2e-07 31.5 9.3 1.2e-07 31.5 9.3 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54489.1 - 1.9e-07 30.9 7.1 1.9e-07 30.9 7.1 3.7 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF54489.1 - 3.2e-07 30.6 8.7 3.2e-07 30.6 8.7 4.1 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 OWF54489.1 - 4.6e-07 29.6 6.5 4.6e-07 29.6 6.5 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF54489.1 - 8e-07 28.8 9.3 8e-07 28.8 9.3 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF54489.1 - 5e-06 26.3 7.9 5e-06 26.3 7.9 3.8 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 DUF4934 PF16288.5 OWF54489.1 - 8.5e-05 22.4 3.1 0.08 12.9 0.1 3.7 1 1 2 3 3 3 2 Domain of unknown function (DUF4934) SBBP PF06739.11 OWF54489.1 - 0.00017 21.5 1.7 0.054 13.5 0.1 3.0 3 0 0 3 3 2 1 Beta-propeller repeat DUF3583 PF12126.8 OWF54489.1 - 0.00042 19.9 0.2 0.0006 19.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-C3HC4_4 PF15227.6 OWF54489.1 - 0.00095 19.3 11.6 0.00095 19.3 11.6 3.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Phytase-like PF13449.6 OWF54489.1 - 0.13 12.2 0.0 27 4.6 0.0 3.3 2 1 0 2 2 2 0 Esterase-like activity of phytase zf-ANAPC11 PF12861.7 OWF54489.1 - 0.17 11.9 5.4 0.16 12.0 1.9 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBP PF02148.19 OWF54489.1 - 2.8 8.3 13.3 0.48 10.8 8.5 2.3 2 1 0 2 2 1 0 Zn-finger in ubiquitin-hydrolases and other protein FH2 PF02181.23 OWF54490.1 - 1.8e-57 195.2 5.2 4.7e-57 193.8 5.2 1.7 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OWF54490.1 - 2.6e-25 89.2 3.9 2.6e-25 89.2 3.9 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OWF54490.1 - 3.7e-14 52.7 0.2 1.2e-13 51.1 0.2 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain CheZ PF04344.13 OWF54490.1 - 0.022 14.7 0.3 0.067 13.1 0.3 1.9 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Bacillus_HBL PF05791.11 OWF54490.1 - 0.034 14.0 0.7 0.12 12.2 0.7 1.9 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF5409 PF17421.2 OWF54490.1 - 0.046 14.4 0.1 0.15 12.8 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5409) zf-C3HC4 PF00097.25 OWF54490.1 - 0.29 11.1 3.5 1.8 8.5 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FPP PF05911.11 OWF54491.1 - 1.2 7.3 48.8 1 7.4 10.0 3.1 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil MbeD_MobD PF04899.12 OWF54491.1 - 2 8.6 7.4 2.5 8.3 0.5 3.7 4 0 0 4 4 4 0 MbeD/MobD like Snurportin1 PF11538.8 OWF54491.1 - 3.2 8.0 7.5 5.8 7.2 2.9 3.4 2 0 0 2 2 2 0 Snurportin1 DUF3287 PF11690.8 OWF54491.1 - 7.7 6.2 14.7 0.21 11.3 2.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) 7tm_1 PF00001.21 OWF54492.1 - 3.5e-58 197.0 11.4 4.4e-58 196.7 11.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF54492.1 - 8.6e-12 45.0 18.9 2.2e-08 33.8 9.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF54492.1 - 1.2e-10 41.5 11.9 1.2e-10 41.5 11.9 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF54492.1 - 1.5e-06 28.2 9.1 1.5e-06 28.2 9.1 1.8 2 0 0 2 2 2 1 Olfactory receptor HemolysinCabind PF00353.19 OWF54493.1 - 1.2e-13 50.8 43.7 0.0018 18.2 5.6 5.8 2 1 3 6 6 6 6 RTX calcium-binding nonapeptide repeat (4 copies) Tcp10_C PF07202.13 OWF54493.1 - 1.6e-13 51.0 30.0 0.0008 19.4 11.4 4.9 1 1 4 5 5 5 5 T-complex protein 10 C-terminus DUF4573 PF15140.6 OWF54493.1 - 2e-12 47.3 0.0 2.1e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) PQQ_3 PF13570.6 OWF54493.1 - 8.5e-09 35.6 11.0 3.2 8.4 0.0 7.2 4 2 1 5 5 5 3 PQQ-like domain DUF2119 PF09892.9 OWF54493.1 - 1.1e-05 24.8 1.4 2.2 7.6 0.7 3.5 1 1 2 3 3 3 3 Uncharacterized protein conserved in archaea (DUF2119) DUF2016 PF09436.10 OWF54493.1 - 0.0003 20.5 0.0 9.5 6.1 0.0 4.8 1 1 4 5 5 5 1 Domain of unknown function (DUF2016) NusG_II PF07009.11 OWF54493.1 - 0.066 13.4 13.7 1.5e+04 -3.8 13.6 4.4 1 1 0 1 1 1 0 NusG domain II ETC_C1_NDUFA5 PF04716.14 OWF54493.1 - 0.18 11.6 4.3 0.78 9.6 0.4 2.9 2 1 1 3 3 3 0 ETC complex I subunit conserved region Dec-1 PF04624.14 OWF54493.1 - 2.6 8.0 10.6 15 5.5 0.0 4.4 4 1 0 4 4 4 0 Dec-1 repeat Tcp10_C PF07202.13 OWF54494.1 - 3.5e-13 49.9 26.3 1.2e-05 25.3 11.4 3.5 1 1 2 3 3 3 3 T-complex protein 10 C-terminus DUF4573 PF15140.6 OWF54494.1 - 8.7e-09 35.4 0.0 0.0034 17.2 0.0 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) NusG_II PF07009.11 OWF54494.1 - 0.00019 21.6 16.9 3.1 8.0 1.6 5.5 1 1 2 3 3 3 3 NusG domain II HemolysinCabind PF00353.19 OWF54494.1 - 0.0035 17.3 26.0 0.027 14.5 3.3 7.1 2 1 4 8 8 8 3 RTX calcium-binding nonapeptide repeat (4 copies) Plasmodium_HRP PF05403.11 OWF54494.1 - 0.0056 16.5 17.7 0.039 13.7 6.7 2.0 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) Glyco_hydro2_C5 PF18565.1 OWF54494.1 - 0.33 10.8 14.6 4 7.4 0.7 4.3 1 1 2 4 4 4 0 Glycoside hydrolase family 2 C-terminal domain 5 RibD_C PF01872.17 OWF54494.1 - 1.3 8.9 5.2 2.4e+02 1.4 4.3 4.3 1 1 1 2 2 2 0 RibD C-terminal domain DUF1854 PF08909.11 OWF54494.1 - 2.6 7.9 22.0 12 5.8 0.4 5.4 1 1 7 8 8 8 0 Domain of unknown function (DUF1854) MetallophosN PF16371.5 OWF54494.1 - 4.1 7.7 20.5 12 6.3 0.3 6.1 1 1 7 8 8 8 0 N terminal of Calcineurin-like phosphoesterase RabGAP-TBC PF00566.18 OWF54495.1 - 4.5e-14 52.6 6.2 7e-13 48.7 3.8 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain 7tm_1 PF00001.21 OWF54496.1 - 5.4e-52 176.7 16.6 6.7e-52 176.4 16.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF54496.1 - 1.1e-05 25.3 15.7 0.00015 21.6 15.7 2.2 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF54496.1 - 5.7e-05 22.6 22.1 0.00026 20.5 22.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF54496.1 - 0.00017 21.3 13.9 0.00017 21.3 13.9 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SH3_9 PF14604.6 OWF54497.1 - 1.4e-55 184.9 4.1 5.6e-17 61.3 0.2 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 OWF54497.1 - 9.7e-49 162.8 5.7 4.2e-13 48.7 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 OWF54497.1 - 5.1e-34 115.8 5.4 2.7e-08 33.3 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4_2 PF13923.6 OWF54497.1 - 1.1e-08 34.7 9.1 3.2e-08 33.3 9.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF54497.1 - 6.2e-08 32.4 8.9 1.3e-07 31.4 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF54497.1 - 6.3e-08 32.8 11.0 8.9e-08 32.3 9.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF54497.1 - 7.5e-08 32.3 7.4 2.1e-07 30.9 7.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF54497.1 - 1.1e-06 28.3 6.8 2.4e-06 27.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54497.1 - 1.6e-06 27.9 9.0 3.1e-06 27.1 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF54497.1 - 0.00015 21.5 7.6 0.00033 20.4 7.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF54497.1 - 0.00016 21.4 6.5 0.00037 20.2 6.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OWF54497.1 - 0.00094 19.3 8.0 0.002 18.3 8.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OWF54497.1 - 0.0043 16.8 1.7 0.0043 16.8 1.7 2.7 2 1 1 3 3 2 1 RING-like zinc finger zf-RING_6 PF14835.6 OWF54497.1 - 0.014 15.3 3.3 0.032 14.1 3.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OWF54497.1 - 0.053 13.7 5.5 0.11 12.6 5.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 OWF54497.1 - 0.44 10.7 4.9 1.2 9.3 4.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 OWF54497.1 - 0.59 10.2 4.5 1.7 8.8 4.5 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-rbx1 PF12678.7 OWF54497.1 - 1.4 9.3 6.5 1.4 9.3 4.7 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger domain zinc-ribbons_6 PF07191.12 OWF54497.1 - 2.1 8.4 5.4 4.3 7.4 5.4 1.5 1 0 0 1 1 1 0 zinc-ribbons RAI16-like PF10257.9 OWF54498.1 - 1.7e-78 264.0 9.0 3.9e-78 262.8 9.0 1.6 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Pex19 PF04614.12 OWF54498.1 - 0.031 14.1 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 Pex19 protein family Aa_trans PF01490.18 OWF54499.1 - 1.1e-55 189.0 27.4 1.3e-55 188.8 27.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3885 PF13021.6 OWF54499.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Aa_trans PF01490.18 OWF54500.1 - 2.9e-27 95.4 21.2 3.5e-27 95.2 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SGL PF08450.12 OWF54501.1 - 0.00029 20.5 0.3 2.1 7.9 0.1 3.1 1 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OWF54501.1 - 0.005 16.8 2.3 0.72 10.0 0.5 3.8 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.11 OWF54501.1 - 0.015 15.4 1.1 0.085 13.1 0.2 2.8 3 0 0 3 3 3 0 Two component regulator propeller ProRS-C_1 PF09180.11 OWF54501.1 - 0.22 11.8 1.5 0.49 10.7 0.5 2.2 1 1 1 2 2 2 0 Prolyl-tRNA synthetase, C-terminal zf-B_box PF00643.24 OWF54502.1 - 2.1e-10 40.6 33.5 4.1e-06 26.8 2.9 3.0 3 0 0 3 3 3 2 B-box zinc finger RhoGAP PF00620.27 OWF54503.1 - 3.7e-35 121.0 0.3 1e-34 119.6 0.3 1.8 1 0 0 1 1 1 1 RhoGAP domain RhoGAP-FF1 PF16512.5 OWF54503.1 - 1.1e-26 93.3 7.1 2.7e-24 85.7 0.5 5.2 4 1 1 5 5 5 1 p190-A and -B Rho GAPs FF domain Ras PF00071.22 OWF54503.1 - 2.9e-14 53.0 0.8 1.1e-07 31.6 0.2 4.2 4 0 0 4 4 4 2 Ras family FF PF01846.19 OWF54503.1 - 4e-10 39.7 5.1 0.012 15.8 0.5 4.2 3 0 0 3 3 3 3 FF domain AAA_11 PF13086.6 OWF54503.1 - 1.3 8.8 12.1 3.3 7.4 0.7 2.5 2 0 0 2 2 2 0 AAA domain Presenilin PF01080.17 OWF54503.1 - 1.9 7.2 4.1 3.8 6.2 4.1 1.4 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 OWF54503.1 - 6.1 5.6 16.7 14 4.4 16.7 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Skp1 PF01466.19 OWF54504.1 - 2.3e-29 101.2 0.6 5.5e-29 100.0 0.6 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OWF54504.1 - 1.7e-28 98.6 0.4 4.4e-28 97.2 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Pkinase PF00069.25 OWF54505.1 - 5.1e-32 111.3 0.0 1.6e-24 86.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OWF54505.1 - 5.2e-30 104.6 0.1 2.8e-19 69.4 0.0 3.5 2 1 1 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 OWF54505.1 - 0.01 15.2 0.0 0.036 13.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF54505.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OWF54506.1 - 4.6e-40 137.7 0.0 8.8e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF54506.1 - 7.1e-33 114.0 0.0 6.7e-32 110.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OWF54506.1 - 0.0021 17.4 0.1 0.0048 16.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OWF54506.1 - 0.0034 16.4 0.3 0.0055 15.7 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Phage_portal PF04860.12 OWF54506.1 - 0.054 12.7 0.1 1.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Phage portal protein APH PF01636.23 OWF54506.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Alpha-amylase_C PF02806.18 OWF54507.1 - 2.6e-21 75.9 0.1 6.2e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 OWF54507.1 - 7.4e-14 51.9 0.0 2.3e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 OWF54507.1 - 3.7e-12 46.5 1.8 6.3e-11 42.4 0.0 2.6 2 1 1 3 3 3 1 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 OWF54507.1 - 0.083 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Bromo_TP PF07524.13 OWF54508.1 - 2.4e-23 81.9 0.4 4.7e-22 77.8 0.2 2.1 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 OWF54508.1 - 7.1e-20 71.3 1.2 7.1e-20 71.3 1.2 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 OWF54508.1 - 0.0023 18.0 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone-fold protein CENP-S PF15630.6 OWF54508.1 - 0.025 15.0 0.1 0.29 11.5 0.0 2.2 1 1 1 2 2 2 0 CENP-S protein RNA_pol PF00940.19 OWF54508.1 - 0.07 12.0 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase TFIID-31kDa PF02291.15 OWF54508.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1658 PF07871.11 OWF54508.1 - 0.13 12.2 1.7 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) ACT PF01842.25 OWF54508.1 - 0.19 11.5 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 ACT domain DEAD PF00270.29 OWF54509.1 - 9.3e-39 133.0 0.7 3.4e-38 131.2 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF54509.1 - 2.2e-23 82.7 1.3 1.2e-22 80.3 0.6 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF54509.1 - 4.6e-07 30.0 6.2 1.9e-06 28.0 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DDHD PF02862.17 OWF54509.1 - 0.038 14.1 3.3 0.074 13.2 3.3 1.5 1 0 0 1 1 1 0 DDHD domain SOBP PF15279.6 OWF54509.1 - 1 9.9 5.7 2.1 8.9 5.7 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.13 OWF54509.1 - 1.4 8.8 25.0 2.5 7.9 25.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF5523 PF17661.1 OWF54509.1 - 5.8 6.5 25.4 13 5.3 25.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Mating_C PF12737.7 OWF54509.1 - 7.7 5.6 14.4 15 4.7 14.4 1.4 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Fic PF02661.18 OWF54510.1 - 7.7e-25 87.6 0.4 3.6e-24 85.5 0.0 2.2 2 1 0 2 2 2 1 Fic/DOC family TPR_1 PF00515.28 OWF54510.1 - 8.9e-08 31.6 0.3 0.0047 16.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF54510.1 - 1.1e-07 31.4 0.3 0.00011 22.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF54510.1 - 5.9e-06 26.5 1.1 1.6e-05 25.1 0.6 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF54510.1 - 2.7e-05 24.6 0.1 0.017 15.9 0.0 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF54510.1 - 0.00031 20.3 0.0 0.0021 17.7 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 OWF54510.1 - 0.00039 20.6 0.1 0.0026 18.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF54510.1 - 0.00071 19.4 1.0 0.068 13.1 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 OWF54510.1 - 0.0014 18.6 1.2 0.0085 16.1 0.3 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 OWF54510.1 - 0.0014 19.2 0.0 0.003 18.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OWF54510.1 - 0.0085 16.2 0.3 0.26 11.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF54510.1 - 0.014 15.8 0.0 0.034 14.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF54510.1 - 0.059 13.4 0.2 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RmuC PF02646.16 OWF54510.1 - 0.1 11.7 0.5 1.4 8.0 0.1 2.1 2 0 0 2 2 2 0 RmuC family FAT PF02259.23 OWF54510.1 - 0.15 11.3 0.3 0.32 10.2 0.3 1.4 1 1 0 1 1 1 0 FAT domain Med28 PF11594.8 OWF54510.1 - 0.17 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 PKD_channel PF08016.12 OWF54511.1 - 2.8e-68 230.5 16.0 2.8e-68 230.5 16.0 2.0 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 OWF54511.1 - 1.9e-15 57.5 0.0 2.2e-14 54.0 0.0 2.9 2 0 0 2 2 2 1 PLAT/LH2 domain I-set PF07679.16 OWF54511.1 - 5.4e-12 45.6 0.1 8.7e-09 35.3 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF54511.1 - 1e-10 41.8 0.9 1e-07 32.2 0.3 2.9 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 OWF54511.1 - 5.3e-10 39.8 0.3 5.3e-10 39.8 0.3 4.4 4 0 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 OWF54511.1 - 2.7e-05 24.2 0.0 2.7e-05 24.2 0.0 4.2 3 1 0 3 3 3 2 Immunoglobulin domain Receptor_2B4 PF11465.8 OWF54511.1 - 0.0087 16.2 1.2 8.7 6.6 0.0 4.1 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 TFIIA PF03153.13 OWF54511.1 - 0.22 11.5 22.3 0.41 10.6 22.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Endostatin PF06482.11 OWF54511.1 - 0.39 10.1 13.6 0.94 8.9 13.6 1.6 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Lin-8 PF03353.15 OWF54511.1 - 3.8 7.0 13.3 7.7 6.0 13.3 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3531 PF12049.8 OWF54512.1 - 0.0046 16.9 18.6 3 7.8 0.1 6.7 2 1 4 7 7 7 3 Protein of unknown function (DUF3531) Toxin_19 PF08088.12 OWF54512.1 - 0.045 13.9 13.0 79 3.5 1.0 7.6 8 1 0 8 8 8 0 Conotoxin I-superfamily DUF4520 PF15016.6 OWF54512.1 - 0.068 13.3 0.3 4.4 7.5 0.3 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4520) Thy1 PF02511.15 OWF54512.1 - 0.22 11.3 0.0 36 4.1 0.0 3.0 2 1 0 2 2 2 0 Thymidylate synthase complementing protein 7tm_1 PF00001.21 OWF54513.1 - 0.00062 19.2 15.2 0.00075 18.9 14.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GlutR_dimer PF00745.20 OWF54514.1 - 0.0016 18.8 0.3 0.011 16.1 0.1 2.3 1 1 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain IPK PF03770.16 OWF54515.1 - 3.5e-24 85.8 0.5 6.1e-24 85.0 0.5 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase EGF PF00008.27 OWF54516.1 - 1.2e-69 230.1 276.4 3e-08 33.8 7.2 20.7 20 0 0 20 20 19 17 EGF-like domain CUB PF00431.20 OWF54516.1 - 1.3e-57 192.8 0.1 3.9e-24 85.1 0.0 4.9 4 0 0 4 4 4 3 CUB domain Ephrin_rec_like PF07699.13 OWF54516.1 - 1.1e-53 178.8 112.2 8.3e-11 41.5 5.3 11.1 9 1 1 10 10 9 7 Putative ephrin-receptor like hEGF PF12661.7 OWF54516.1 - 2.1e-31 107.5 230.8 0.00026 21.5 7.8 21.7 20 0 0 20 20 20 16 Human growth factor-like EGF Sushi PF00084.20 OWF54516.1 - 2.9e-22 79.0 60.2 2.5e-06 28.0 0.1 10.8 10 0 0 10 10 8 5 Sushi repeat (SCR repeat) HYR PF02494.16 OWF54516.1 - 8.2e-22 77.3 15.1 4.7e-11 42.9 0.6 4.3 3 0 0 3 3 3 3 HYR domain Ldl_recept_a PF00057.18 OWF54516.1 - 3.2e-08 33.6 17.7 3.2e-08 33.6 17.7 8.4 6 1 0 6 6 3 1 Low-density lipoprotein receptor domain class A EGF_CA PF07645.15 OWF54516.1 - 5.5e-08 32.9 28.1 6.9e-07 29.4 8.1 22.8 14 5 9 23 23 18 10 Calcium-binding EGF domain Pentaxin PF00354.17 OWF54516.1 - 5.3e-05 23.0 1.6 0.0001 22.0 1.6 1.5 1 0 0 1 1 1 1 Pentaxin family EGF_3 PF12947.7 OWF54516.1 - 0.00026 21.1 5.7 0.00026 21.1 5.7 20.0 17 2 2 19 19 18 5 EGF domain EGF_2 PF07974.13 OWF54516.1 - 0.0028 18.0 309.8 0.012 15.9 18.8 20.2 19 0 0 19 19 18 13 EGF-like domain Lipase_GDSL_2 PF13472.6 OWF54519.1 - 0.00045 20.6 0.0 0.001 19.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OWF54519.1 - 0.14 12.2 0.0 0.67 9.9 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ras PF00071.22 OWF54520.1 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Ras family zf-B_box PF00643.24 OWF54521.1 - 7.6e-08 32.4 3.2 7.6e-08 32.4 3.2 1.8 2 0 0 2 2 2 1 B-box zinc finger Homeobox_KN PF05920.11 OWF54522.1 - 4e-16 58.6 0.9 1.7e-15 56.6 0.2 2.4 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OWF54522.1 - 2.2e-07 30.6 1.7 2.2e-07 30.6 1.7 2.0 2 0 0 2 2 2 1 Homeodomain Glyco_hydro_63N PF16923.5 OWF54522.1 - 0.022 14.8 0.3 0.022 14.8 0.3 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 N-terminal domain MRP-S32 PF10210.9 OWF54522.1 - 0.15 12.6 1.0 0.46 11.1 0.9 1.9 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Kazal_2 PF07648.15 OWF54523.1 - 1.2e-08 35.0 0.5 2.6e-08 33.8 0.5 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF54523.1 - 3.6e-08 33.3 1.9 7.2e-08 32.3 1.9 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Cucumo_2B PF03263.13 OWF54523.1 - 1.6 9.3 8.0 0.43 11.1 0.7 2.4 2 0 0 2 2 2 0 Cucumovirus protein 2B C1q PF00386.21 OWF54524.1 - 1.3e-21 77.2 0.0 2.6e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF54524.1 - 8.1e-07 29.0 0.6 1.6e-06 28.1 0.6 1.4 1 0 0 1 1 1 1 BclA C-terminal domain bZIP_2 PF07716.15 OWF54524.1 - 0.01 15.9 1.1 0.49 10.5 0.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 OWF54524.1 - 0.041 14.2 1.0 0.36 11.2 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Lipoprotein_6 PF01441.19 OWF54524.1 - 0.049 13.6 0.3 0.088 12.8 0.3 1.4 1 0 0 1 1 1 0 Lipoprotein DUF3972 PF13118.6 OWF54524.1 - 0.081 13.4 0.5 0.15 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) PRKG1_interact PF15898.5 OWF54524.1 - 0.086 13.7 1.3 0.15 12.9 1.3 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TNF PF00229.18 OWF54524.1 - 0.092 12.7 0.4 0.45 10.5 0.2 2.2 2 1 0 2 2 2 0 TNF(Tumour Necrosis Factor) family Baculo_F PF12259.8 OWF54524.1 - 0.32 9.5 1.8 0.41 9.1 1.8 1.1 1 0 0 1 1 1 0 Baculovirus F protein bZIP_1 PF00170.21 OWF54524.1 - 0.96 9.6 2.5 2.9 8.1 0.3 2.3 3 0 0 3 3 3 0 bZIP transcription factor C1q PF00386.21 OWF54525.1 - 3.3e-19 69.3 0.1 3.3e-19 69.3 0.1 1.6 2 0 0 2 2 2 1 C1q domain BclA_C PF18573.1 OWF54525.1 - 0.0028 17.6 1.4 0.0049 16.8 1.4 1.4 1 0 0 1 1 1 1 BclA C-terminal domain CtIP_N PF10482.9 OWF54525.1 - 0.054 13.5 1.4 1.8 8.6 0.2 2.1 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain CTNNBL PF08216.11 OWF54525.1 - 0.061 13.5 0.9 0.11 12.6 0.9 1.5 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Rhabdo_NV PF02484.15 OWF54525.1 - 0.13 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein bZIP_1 PF00170.21 OWF54525.1 - 0.3 11.2 1.2 0.43 10.7 0.4 1.6 2 0 0 2 2 2 0 bZIP transcription factor DUF4744 PF15918.5 OWF54526.1 - 0.00096 19.9 1.4 0.0014 19.4 1.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4744) PI3K_P85_iSH2 PF16454.5 OWF54526.1 - 0.017 14.7 0.1 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain UBA_2 PF08587.11 OWF54526.1 - 0.037 14.1 15.9 1.7e+04 -4.0 15.9 4.9 1 1 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF1110 PF06533.12 OWF54526.1 - 0.08 12.9 0.1 0.17 11.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1110) DUF713 PF05218.14 OWF54526.1 - 0.14 11.8 0.4 1 9.1 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF713) NYN_YacP PF05991.11 OWF54526.1 - 9.8 6.1 12.0 78 3.1 0.4 4.1 1 1 1 2 2 2 0 YacP-like NYN domain TIR PF01582.20 OWF54527.1 - 1.1e-23 84.0 0.0 1.8e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF54527.1 - 3.1e-17 63.3 0.1 2.7e-16 60.3 0.1 2.2 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 OWF54527.1 - 1.9e-14 53.5 27.3 0.00011 22.5 0.5 7.0 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF54527.1 - 4.5e-12 45.5 35.7 0.00057 19.6 4.7 6.0 3 3 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 OWF54527.1 - 0.0013 18.2 9.5 0.22 11.0 0.1 3.4 1 1 2 4 4 4 2 Leucine-rich repeat DUF1863 PF08937.11 OWF54527.1 - 0.0054 17.0 0.3 0.038 14.3 0.3 2.2 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) FNIP PF05725.12 OWF54527.1 - 0.0066 16.6 0.2 0.0066 16.6 0.2 4.4 4 0 0 4 4 4 1 FNIP Repeat TIR PF01582.20 OWF54528.1 - 1.7e-23 83.3 0.0 2.8e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF54528.1 - 2e-19 69.1 29.6 0.0004 20.1 3.4 7.4 3 2 3 7 7 7 6 Leucine rich repeat TIR_2 PF13676.6 OWF54528.1 - 5.4e-15 56.0 0.0 1.1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 OWF54528.1 - 5.5e-13 48.9 40.1 0.00095 19.5 0.7 8.2 8 1 1 9 9 9 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF54528.1 - 6.4e-07 29.4 16.2 0.0057 16.6 0.2 4.5 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OWF54528.1 - 0.00019 21.5 18.7 4.9 8.1 0.1 8.3 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 OWF54528.1 - 0.0098 15.9 25.6 0.8 9.9 0.4 7.1 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.6 OWF54530.1 - 2.7e-27 94.3 54.6 7.3e-09 35.3 0.2 8.5 3 3 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 OWF54530.1 - 2.4e-23 81.8 57.4 0.00061 20.1 2.2 9.0 8 1 0 8 8 8 7 Leucine Rich repeats (2 copies) TIR PF01582.20 OWF54530.1 - 2.1e-19 70.0 0.1 3.5e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF54530.1 - 6.3e-17 62.3 0.1 7.8e-16 58.8 0.1 2.3 2 0 0 2 2 2 1 TIR domain LRR_9 PF14580.6 OWF54530.1 - 6e-09 35.6 21.1 0.0045 16.5 0.9 4.6 2 2 1 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 OWF54530.1 - 4.6e-07 29.8 20.4 0.0022 18.0 0.7 4.5 2 1 3 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 OWF54530.1 - 3.2e-05 23.4 4.7 3.2e-05 23.4 4.7 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 OWF54530.1 - 0.0095 16.0 0.4 0.032 14.4 0.4 2.0 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_1 PF00560.33 OWF54530.1 - 0.012 16.0 44.8 20 6.2 0.1 12.6 12 1 0 12 12 12 0 Leucine Rich Repeat DUF1863 PF08937.11 OWF54530.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.6 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) cEGF PF12662.7 OWF54531.1 - 0.00028 20.7 10.8 0.062 13.3 3.9 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 OWF54531.1 - 0.00058 20.0 7.6 0.14 12.4 1.2 3.0 2 0 0 2 2 2 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 OWF54531.1 - 0.0018 18.5 7.6 0.04 14.2 0.9 2.6 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 OWF54531.1 - 0.0052 17.0 7.2 0.51 10.6 0.7 2.8 2 0 0 2 2 2 2 EGF domain Plasmod_Pvs28 PF06247.11 OWF54531.1 - 0.011 16.0 0.6 3 8.2 0.1 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain EGF PF00008.27 OWF54531.1 - 0.037 14.3 10.8 1.6 9.1 1.9 2.8 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 OWF54531.1 - 0.66 10.7 11.1 3.4 8.4 0.3 3.2 3 0 0 3 3 3 0 Human growth factor-like EGF fn3 PF00041.21 OWF54532.1 - 0.00012 22.3 0.1 0.0003 21.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Tissue_fac PF01108.17 OWF54532.1 - 0.081 12.8 0.1 0.28 11.0 0.1 1.9 1 1 0 1 1 1 0 Tissue factor SusE PF14292.6 OWF54532.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 SusE outer membrane protein Ldl_recept_b PF00058.17 OWF54533.1 - 1.1e-08 35.4 3.6 0.0033 17.9 0.0 5.3 6 0 0 6 6 6 2 Low-density lipoprotein receptor repeat class B Arylesterase PF01731.20 OWF54533.1 - 6e-05 23.2 0.0 0.0017 18.5 0.0 3.2 3 1 0 3 3 3 1 Arylesterase FXa_inhibition PF14670.6 OWF54533.1 - 6.5e-05 23.1 9.2 0.00012 22.2 9.2 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 OWF54533.1 - 0.049 13.2 0.6 3.4 7.2 0.0 3.2 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region HYR PF02494.16 OWF54534.1 - 2.2e-10 40.7 0.2 8.5e-10 38.8 0.2 2.1 1 0 0 1 1 1 1 HYR domain Ephrin_rec_like PF07699.13 OWF54534.1 - 8e-07 28.7 3.7 8e-07 28.7 3.7 5.7 5 1 1 6 6 6 1 Putative ephrin-receptor like Adeno_E3_CR2 PF02439.15 OWF54534.1 - 0.027 14.2 1.9 0.051 13.3 1.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PQQ_3 PF13570.6 OWF54534.1 - 0.03 14.8 0.3 2.8 8.6 0.1 3.4 2 0 0 2 2 2 0 PQQ-like domain SKG6 PF08693.10 OWF54534.1 - 0.058 12.8 0.8 0.12 11.9 0.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3261 PF11659.8 OWF54534.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) TPR_12 PF13424.6 OWF54535.1 - 6.9e-23 80.7 11.8 9.3e-08 32.3 3.1 5.6 4 1 1 5 5 5 5 Tetratricopeptide repeat Ank_2 PF12796.7 OWF54535.1 - 9.4e-19 67.8 0.4 5.6e-13 49.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF54535.1 - 4.8e-16 58.6 1.5 6.1e-07 29.6 0.1 4.0 2 1 2 4 4 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF54535.1 - 5.8e-15 55.4 0.1 1.4e-09 38.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TPR_2 PF07719.17 OWF54535.1 - 1.3e-12 46.8 11.8 0.27 11.4 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat Ank_3 PF13606.6 OWF54535.1 - 1.4e-12 46.6 0.3 0.0016 18.8 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OWF54535.1 - 1.8e-10 40.8 1.8 0.0012 19.2 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat TPR_1 PF00515.28 OWF54535.1 - 4.6e-10 38.9 14.2 0.15 11.9 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF54535.1 - 6.2e-10 39.0 6.1 0.00013 21.5 4.8 3.2 1 1 2 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 OWF54535.1 - 1.5e-09 37.3 15.5 0.00096 19.2 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF54535.1 - 8.3e-09 34.9 14.2 0.13 12.3 0.2 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat LRR_6 PF13516.6 OWF54535.1 - 1e-08 34.5 28.8 0.019 15.0 0.9 8.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 OWF54535.1 - 1.1e-05 25.7 19.6 0.0011 19.4 1.7 5.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) TPR_10 PF13374.6 OWF54535.1 - 0.0001 22.0 10.4 2.5 8.1 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF54535.1 - 0.0063 17.2 1.2 32 5.7 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF573 PF04504.14 OWF54535.1 - 0.0073 16.9 1.2 0.036 14.7 1.2 2.2 1 0 0 1 1 1 1 Protein of unknown function, DUF573 LRR_8 PF13855.6 OWF54535.1 - 0.013 15.2 14.9 0.048 13.4 2.7 4.5 2 2 1 3 3 3 0 Leucine rich repeat TPR_19 PF14559.6 OWF54535.1 - 0.13 12.8 6.1 2.6 8.6 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1843 PF08898.10 OWF54535.1 - 0.67 10.5 5.3 3.2 8.3 0.0 3.7 4 0 0 4 4 2 0 Domain of unknown function (DUF1843) ANAPC3 PF12895.7 OWF54535.1 - 1.8 8.9 14.1 1.3 9.3 0.3 4.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Gastrin PF00918.17 OWF54535.1 - 4.5 8.2 7.8 1.4 9.9 0.1 3.8 3 1 0 3 3 2 0 Gastrin/cholecystokinin family SHNi-TPR PF10516.9 OWF54535.1 - 5 6.7 11.1 1.9 8.0 0.0 4.0 5 0 0 5 5 5 0 SHNi-TPR TPR_6 PF13174.6 OWF54535.1 - 6.4 7.6 10.8 61 4.6 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 OWF54535.1 - 7.7 6.6 10.1 4.5 7.4 0.9 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 OWF54536.1 - 1.5e-39 136.0 6.5 1.9e-38 132.3 6.5 2.2 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family SDA1 PF05285.12 OWF54537.1 - 6 6.2 18.5 3.7 6.9 2.5 2.1 1 1 1 2 2 2 0 SDA1 zf-C2H2 PF00096.26 OWF54538.1 - 2.8e-22 77.9 20.2 3.4e-06 27.2 0.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF54538.1 - 1.9e-15 56.2 18.4 0.00032 21.3 1.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF54538.1 - 2.8e-14 52.8 17.0 1.1e-06 28.8 0.2 4.6 4 0 0 4 4 4 3 Zinc-finger double domain XPA_N PF01286.18 OWF54538.1 - 2.6e-07 30.6 5.9 0.013 15.5 0.1 4.3 4 0 0 4 4 4 2 XPA protein N-terminal zf-met PF12874.7 OWF54538.1 - 4.6e-06 26.8 11.3 0.016 15.5 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF54538.1 - 4.1e-05 23.5 13.4 0.00074 19.5 0.8 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF54538.1 - 8.4e-05 22.7 13.2 0.0035 17.6 0.2 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 OWF54538.1 - 0.0005 20.0 2.7 0.0025 17.8 0.4 2.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid zf_UBZ PF18439.1 OWF54538.1 - 0.0033 17.0 1.8 6.3 6.5 0.1 3.8 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 OWF54538.1 - 0.0034 17.7 4.8 0.0034 17.7 4.8 2.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon Actin_micro PF17003.5 OWF54538.1 - 0.0085 15.3 1.6 0.0085 15.3 1.6 2.9 2 1 1 3 3 3 1 Putative actin-like family TRAF6_Z2 PF18048.1 OWF54538.1 - 0.015 15.4 2.5 0.75 9.9 0.9 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HE PF16278.5 OWF54538.1 - 0.15 12.5 0.2 0.15 12.5 0.2 3.5 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 OWF54538.1 - 0.32 10.8 15.6 0.58 10.0 0.7 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 OWF54538.1 - 0.54 11.1 7.1 0.65 10.8 0.4 2.8 2 0 0 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 OWF54538.1 - 0.63 10.2 8.9 1.2 9.3 0.7 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 OWF54538.1 - 0.7 9.9 14.7 0.39 10.7 0.6 3.9 4 0 0 4 4 3 0 zinc-finger of a C2HC-type IBR PF01485.21 OWF54538.1 - 1.3 9.3 12.7 0.5 10.6 2.9 2.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_2 PF12756.7 OWF54538.1 - 1.4 9.3 14.0 6.5 7.2 1.2 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 OWF54538.1 - 4.3 7.3 7.0 20 5.2 0.1 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger MORN PF02493.20 OWF54539.1 - 1.1e-27 94.2 73.4 0.00021 21.0 0.2 8.9 9 0 0 9 9 9 8 MORN repeat DAGK_cat PF00781.24 OWF54540.1 - 1.6e-25 89.2 0.1 2.5e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DsbD_2 PF13386.6 OWF54540.1 - 0.00071 19.6 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF3786 PF12654.7 OWF54540.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) DAGK_cat PF00781.24 OWF54541.1 - 2.6e-24 85.2 0.0 5.3e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ras PF00071.22 OWF54542.1 - 1e-24 87.0 0.0 1.2e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF54542.1 - 1.2e-10 41.6 0.2 2.3e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF54542.1 - 1.9e-08 33.9 0.1 2.3e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF54542.1 - 1.1e-05 25.5 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF54542.1 - 0.0073 16.6 0.2 0.015 15.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 OWF54542.1 - 0.011 15.0 1.1 0.091 12.0 0.0 2.1 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 OWF54542.1 - 0.037 14.1 0.2 4.8 7.2 0.0 2.8 1 1 2 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 OWF54542.1 - 0.05 13.1 0.6 0.11 12.0 0.1 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 OWF54542.1 - 0.05 13.8 0.3 0.074 13.2 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OWF54542.1 - 0.083 12.6 0.8 0.28 10.9 0.8 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OWF54542.1 - 0.096 12.6 0.3 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OWF54542.1 - 0.1 13.0 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OWF54542.1 - 0.1 12.3 0.6 4.4 7.1 0.1 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OWF54542.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region TPR_2 PF07719.17 OWF54543.1 - 6.1e-38 125.9 12.1 2.5e-05 24.0 0.5 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 OWF54543.1 - 1.9e-33 112.9 15.9 7.7e-05 22.4 0.7 8.8 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 OWF54543.1 - 7e-33 110.1 16.3 1.7e-05 24.7 0.1 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 OWF54543.1 - 4e-26 90.4 9.3 4e-09 36.0 0.0 9.1 4 3 5 9 9 9 4 TPR repeat TPR_12 PF13424.6 OWF54543.1 - 4.8e-21 74.8 16.7 7.7e-06 26.1 0.3 7.1 5 3 1 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 OWF54543.1 - 5.1e-21 75.0 0.4 0.0003 21.4 0.6 6.4 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 OWF54543.1 - 9.5e-20 70.9 14.6 8.9e-07 29.3 0.1 5.7 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF54543.1 - 5.6e-18 63.6 3.0 0.011 15.7 0.2 7.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OWF54543.1 - 4.6e-17 61.9 0.0 0.00034 20.7 0.0 6.1 2 2 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OWF54543.1 - 3.5e-16 58.5 4.1 0.014 16.2 0.7 8.4 4 3 5 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF54543.1 - 8.4e-16 58.0 20.0 0.00011 22.3 0.3 6.0 2 2 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OWF54543.1 - 3.3e-14 52.1 13.6 0.00017 21.8 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 OWF54543.1 - 5.3e-10 39.3 16.8 0.45 11.3 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat NARP1 PF12569.8 OWF54543.1 - 1.3e-09 37.6 10.6 2.5e-07 30.0 0.2 3.9 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 OWF54543.1 - 3.2e-09 36.4 4.8 0.00013 21.3 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 OWF54543.1 - 1.3e-07 31.8 1.0 0.0041 17.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 OWF54543.1 - 1.5e-06 27.9 7.6 0.099 12.0 0.3 3.7 3 2 0 3 3 3 2 Coatomer epsilon subunit TPR_10 PF13374.6 OWF54543.1 - 1.6e-06 27.8 11.7 0.48 10.4 0.1 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OWF54543.1 - 0.00012 22.1 1.2 0.27 11.2 0.2 2.9 3 0 0 3 3 3 2 Virulence factor membrane-bound polymerase, C-terminal DUF4810 PF16068.5 OWF54543.1 - 0.00017 22.0 1.3 4.9 7.8 0.1 4.3 4 1 1 5 5 4 2 Domain of unknown function (DUF4810) PknG_TPR PF16918.5 OWF54543.1 - 0.00024 19.9 0.7 0.33 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_MalT PF17874.1 OWF54543.1 - 0.00068 19.1 5.2 0.0083 15.5 0.1 3.3 2 1 0 3 3 3 1 MalT-like TPR region DUF2989 PF11207.8 OWF54543.1 - 0.0035 17.1 6.5 0.44 10.3 1.3 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2989) HrpB1_HrpK PF09613.10 OWF54543.1 - 0.011 15.4 2.5 0.34 10.5 0.1 3.4 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 OWF54543.1 - 0.018 14.8 4.5 4.8 6.8 0.0 3.6 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain ChAPs PF09295.10 OWF54543.1 - 0.021 13.8 2.1 0.42 9.6 0.3 2.8 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 OWF54543.1 - 0.027 14.2 6.9 1.5 8.5 0.0 4.0 2 2 2 4 4 4 0 26S proteasome subunit RPN7 Paf67 PF10255.9 OWF54543.1 - 0.1 11.6 2.9 0.37 9.7 0.2 2.6 2 1 1 3 3 3 0 RNA polymerase I-associated factor PAF67 Fis1_TPR_C PF14853.6 OWF54543.1 - 0.6 10.2 5.6 12 6.1 0.1 3.8 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 OWF54543.1 - 0.98 9.8 5.0 5.2 7.5 0.1 3.4 3 2 0 3 3 3 0 Bacterial transcriptional activator domain ANAPC5 PF12862.7 OWF54543.1 - 1.8 8.7 5.0 31 4.7 1.3 4.0 1 1 3 4 4 3 0 Anaphase-promoting complex subunit 5 Transglut_N PF00868.20 OWF54544.1 - 7.1e-29 100.6 0.0 1.3e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 OWF54544.1 - 2.9e-18 66.0 0.0 4.2e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 OWF54544.1 - 2.8e-17 63.2 0.3 6e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF3994 PF13159.6 OWF54544.1 - 0.019 15.5 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) CLCA PF08434.11 OWF54545.1 - 8.4e-65 218.7 0.3 1.4e-64 218.0 0.3 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal RTTN_N PF14726.6 OWF54546.1 - 1.4e-30 105.9 6.4 2.1e-30 105.4 1.5 3.7 2 0 0 2 2 2 1 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.22 OWF54546.1 - 2e-05 24.4 6.3 0.18 12.1 0.2 6.4 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 OWF54546.1 - 0.0011 18.9 0.5 0.0011 18.9 0.5 6.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF383 PF04063.14 OWF54546.1 - 0.0013 18.5 3.1 0.0013 18.5 3.1 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF383) DUF3361 PF11841.8 OWF54546.1 - 0.0015 18.5 0.7 0.023 14.6 0.3 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) RICTOR_M PF14666.6 OWF54546.1 - 0.0034 17.1 2.6 0.93 9.3 0.3 4.1 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain HEAT_2 PF13646.6 OWF54546.1 - 0.0058 17.0 0.4 0.39 11.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats DUF2019 PF09450.10 OWF54546.1 - 0.076 13.0 0.0 0.67 9.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) Cnd1 PF12717.7 OWF54546.1 - 0.1 12.6 5.2 5.2 7.1 0.7 3.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OWF54546.1 - 0.14 12.3 0.1 0.57 10.3 0.1 2.1 1 0 0 1 1 1 0 Parkin co-regulated protein SUIM_assoc PF16619.5 OWF54546.1 - 9.4 6.4 8.0 45 4.2 8.0 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 OWF54547.1 - 1.9e-63 211.0 7.4 4.8e-16 59.1 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF54547.1 - 3.8e-41 134.4 9.7 9.9e-05 22.5 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 OWF54547.1 - 1.2e-37 126.7 10.5 4.5e-06 26.9 0.2 10.1 10 1 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 OWF54547.1 - 4e-35 119.8 3.1 9.5e-08 32.4 0.0 6.7 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF54547.1 - 2.9e-29 100.7 9.7 5.5e-09 36.1 0.1 8.7 3 2 6 9 9 9 8 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF54547.1 - 8.9e-07 29.2 4.0 2e-06 28.1 4.0 1.6 1 0 0 1 1 1 1 SOCS box DLIC PF05783.11 OWF54548.1 - 1.2e-184 614.6 0.0 1.5e-184 614.2 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 OWF54548.1 - 0.00064 20.2 0.0 0.0023 18.4 0.0 1.9 1 1 0 1 1 1 1 ABC transporter Roc PF08477.13 OWF54548.1 - 0.0018 18.5 0.1 0.0049 17.1 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OWF54548.1 - 0.0026 17.0 0.2 0.0056 15.9 0.2 1.6 1 1 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 OWF54548.1 - 0.0098 15.8 0.2 0.9 9.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OWF54548.1 - 0.01 15.4 0.1 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OWF54548.1 - 0.014 15.2 0.2 0.08 12.7 0.0 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 OWF54548.1 - 0.033 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Antimicrobial14 PF08109.11 OWF54549.1 - 0.00059 19.8 9.6 5.9 7.0 0.1 4.1 1 1 5 6 6 6 6 Lactocin 705 family Hairy_orange PF07527.13 OWF54549.1 - 0.032 14.5 9.2 2.2e+02 2.2 0.0 6.7 8 0 0 8 8 8 0 Hairy Orange FERM_M PF00373.18 OWF54549.1 - 0.55 10.6 3.5 37 4.8 0.1 2.7 1 1 3 4 4 4 0 FERM central domain IL12p40_C PF10420.9 OWF54549.1 - 0.69 10.5 7.1 6 7.4 7.1 2.1 1 1 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus KRTAP7 PF15034.6 OWF54549.1 - 1.1 10.2 12.2 28 5.8 0.4 3.6 1 1 4 5 5 5 0 KRTAP type 7 family zf-SAP30 PF13866.6 OWF54549.1 - 2.5 8.3 16.1 84 3.4 1.2 5.5 1 1 3 4 4 4 0 SAP30 zinc-finger Ras PF00071.22 OWF54550.1 - 3.2e-33 114.6 0.1 3.8e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF54550.1 - 1.2e-22 80.3 0.0 1.7e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OWF54550.1 - 2.9e-06 27.3 0.0 3.7e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OWF54550.1 - 5.2e-06 26.0 0.0 7.6e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF54550.1 - 0.00061 19.2 1.3 0.0013 18.2 0.3 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OWF54550.1 - 0.0051 16.7 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OWF54550.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 OWF54550.1 - 0.087 13.1 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OWF54550.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OWF54550.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 OWF54550.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DC_STAMP PF07782.13 OWF54551.1 - 9.2e-49 165.9 1.8 9.2e-49 165.9 1.8 1.7 2 0 0 2 2 2 1 DC-STAMP-like protein DUF3658 PF12395.8 OWF54551.1 - 0.12 12.3 0.5 6.7 6.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function zf-C3HC4_3 PF13920.6 OWF54551.1 - 5.1 7.0 11.6 14 5.7 11.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 OWF54552.1 - 7.9e-18 64.5 20.8 2.7e-05 24.8 0.4 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF54552.1 - 8e-08 32.5 7.1 0.0096 16.2 0.1 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF54552.1 - 1.1e-05 24.5 1.3 0.52 9.2 0.4 3.5 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5334 PF17268.2 OWF54552.1 - 0.1 12.9 0.0 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5334) PFU PF09070.11 OWF54552.1 - 0.18 12.1 0.8 7 6.9 0.1 2.9 2 1 1 3 3 3 0 PFU (PLAA family ubiquitin binding) Neuralized PF07177.12 OWF54553.1 - 3.9e-37 127.5 0.0 9.9e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 Neuralized CTU2 PF10288.9 OWF54553.1 - 1.6e-21 76.7 1.0 4.6e-21 75.2 1.0 1.8 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 OWF54553.1 - 1.6e-05 24.7 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 PP-loop family S4_2 PF13275.6 OWF54553.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 S4 domain PAPS_reduct PF01507.19 OWF54553.1 - 0.14 12.2 0.0 5.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Seadorna_Vp10 PF07322.11 OWF54554.1 - 1.3e-05 24.7 4.2 0.73 9.2 0.3 5.0 1 1 4 5 5 5 3 Seadornavirus Vp10 CopK PF11525.8 OWF54554.1 - 0.015 14.9 15.0 4.1 7.1 0.4 4.2 1 1 2 4 4 4 0 Copper resistance protein K T5orf172 PF10544.9 OWF54554.1 - 0.078 13.5 6.9 33 5.1 2.5 4.4 1 1 1 2 2 2 0 T5orf172 domain DUF4829 PF16111.5 OWF54554.1 - 6.5 7.6 13.3 5.6 7.8 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4829) Seadorna_Vp10 PF07322.11 OWF54555.1 - 1.3e-05 24.8 6.2 3 7.2 0.3 5.1 1 1 4 5 5 5 5 Seadornavirus Vp10 TnpW PF14202.6 OWF54555.1 - 0.042 13.7 8.9 1.2e+02 2.6 0.0 6.0 6 0 0 6 6 6 0 Transposon-encoded protein TnpW CopK PF11525.8 OWF54555.1 - 1.3 8.7 11.6 7.1 6.3 0.4 3.5 1 1 4 5 5 5 0 Copper resistance protein K DUF4829 PF16111.5 OWF54555.1 - 1.3 9.8 12.3 4.7 8.0 6.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4829) AXH PF08517.12 OWF54556.1 - 4.1e-44 149.8 0.1 9.7e-44 148.6 0.1 1.7 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Aminotran_MocR PF12897.7 OWF54557.1 - 0.00074 18.4 3.9 1.4 7.6 0.0 4.2 1 1 4 5 5 5 5 Alanine-glyoxylate amino-transferase DUF656 PF04920.12 OWF54558.1 - 0.0078 16.1 5.3 0.48 10.3 1.0 2.6 1 1 1 2 2 2 2 Family of unknown function (DUF656) TRAP_alpha PF03896.16 OWF54559.1 - 1.8e-107 358.8 0.9 2.1e-107 358.5 0.9 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF11 PF01345.18 OWF54559.1 - 0.071 13.4 0.6 0.18 12.1 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF11 Nop14 PF04147.12 OWF54559.1 - 0.46 8.6 5.0 0.54 8.4 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family Sina PF03145.16 OWF54560.1 - 4.9e-06 26.6 5.2 4.9e-06 26.6 5.2 2.2 1 1 1 2 2 2 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 OWF54560.1 - 7.2e-05 22.6 14.6 7.2e-05 22.6 14.6 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 OWF54560.1 - 0.00017 22.2 5.0 0.00017 22.2 5.0 3.1 2 1 1 3 3 3 1 TRAF-type zinc finger DUF1945 PF09178.10 OWF54560.1 - 0.15 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) NEMP PF10225.9 OWF54561.1 - 0.061 13.0 2.5 0.14 11.8 2.5 1.6 1 1 1 2 2 2 0 NEMP family Peptidase_A24 PF01478.18 OWF54561.1 - 0.17 12.3 6.1 0.11 13.0 2.0 2.2 1 1 1 2 2 2 0 Type IV leader peptidase family Prefoldin PF02996.17 OWF54563.1 - 5.1e-18 65.1 0.4 1.7e-17 63.5 0.0 2.1 2 1 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 OWF54563.1 - 8.3e-09 35.4 0.0 8.3e-09 35.4 0.0 2.7 3 1 0 3 3 3 1 Prefoldin subunit Occludin_ELL PF07303.13 OWF54563.1 - 1 10.1 11.8 1.2 9.9 3.9 2.5 2 0 0 2 2 2 0 Occludin homology domain TPR_MLP1_2 PF07926.12 OWF54563.1 - 2.2 8.3 11.3 3.8 7.6 0.0 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cyclin_N PF00134.23 OWF54564.1 - 7.2e-42 142.1 0.2 1.2e-41 141.4 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OWF54564.1 - 1e-14 54.7 0.0 2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain BtpA PF03437.15 OWF54565.1 - 5.6e-61 206.2 1.7 6.5e-61 206.0 1.7 1.0 1 0 0 1 1 1 1 BtpA family Gln-synt_N PF03951.19 OWF54565.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Ost4 PF10215.9 OWF54566.1 - 3.4 7.6 6.0 0.63 9.9 1.0 2.0 2 0 0 2 2 2 0 Oligosaccaryltransferase Spo0A_C PF08769.11 OWF54567.1 - 0.0082 16.2 2.9 9 6.5 0.0 5.3 4 1 3 7 7 7 1 Sporulation initiation factor Spo0A C terminal Pur_ac_phosph_N PF16656.5 OWF54567.1 - 0.051 14.1 2.9 1.2 9.7 0.0 3.6 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF1011 PF06237.12 OWF54569.1 - 3.2e-35 120.4 8.0 3.2e-35 120.4 8.0 3.8 4 1 1 5 5 5 1 Protein of unknown function (DUF1011) Prion_bPrPp PF11587.8 OWF54569.1 - 5.7 6.9 6.4 12 5.8 1.1 3.1 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal RNA_pol_A_bac PF01000.26 OWF54570.1 - 8.7e-36 122.7 0.2 1.4e-35 122.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OWF54570.1 - 1.1e-15 56.8 0.0 1.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CREPT PF16566.5 OWF54571.1 - 8.3e-56 188.3 1.8 8.3e-56 188.3 1.8 2.5 3 0 0 3 3 3 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 OWF54571.1 - 1e-18 67.9 0.0 1e-18 67.9 0.0 3.4 4 1 0 4 4 4 1 RNA polymerase II-binding domain. CTK3 PF12243.8 OWF54571.1 - 0.022 14.8 0.2 0.042 13.9 0.2 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF29 PF01724.16 OWF54571.1 - 0.15 12.3 6.0 1.1 9.5 0.9 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF29 HHH_3 PF12836.7 OWF54572.1 - 9.9e-39 131.4 0.4 4.6e-18 65.2 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 OWF54572.1 - 1.2e-15 56.4 0.1 0.003 17.4 0.0 4.9 5 0 0 5 5 5 4 Helix-hairpin-helix motif HHH_6 PF14579.6 OWF54572.1 - 3.4e-08 33.6 0.0 7.2e-05 23.0 0.0 2.8 2 1 1 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 OWF54572.1 - 3e-07 30.9 0.9 0.81 10.3 0.0 4.8 5 0 0 5 5 5 2 Helix-hairpin-helix domain HHH_2 PF12826.7 OWF54572.1 - 2e-06 27.8 0.2 1.2 9.3 0.0 3.9 4 0 0 4 4 4 3 Helix-hairpin-helix motif PsbU PF06514.11 OWF54572.1 - 2e-05 24.5 0.1 0.0018 18.2 0.0 3.4 3 0 0 3 3 3 1 Photosystem II 12 kDa extrinsic protein (PsbU) T2SSK PF03934.13 OWF54572.1 - 0.0015 18.0 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K Exo_endo_phos PF03372.23 OWF54572.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3725 PF12523.8 OWF54573.1 - 3.7e-05 23.9 0.0 12 6.3 0.0 6.9 7 3 2 9 9 9 1 Protein of unknown function (DUF3725) F-box-like_2 PF13013.6 OWF54573.1 - 0.00016 21.6 0.3 17 5.4 0.1 6.2 3 3 0 3 3 3 1 F-box-like domain DUF2888 PF11135.8 OWF54573.1 - 0.00033 20.6 8.6 2.7 7.9 0.0 6.5 4 3 4 8 8 8 2 Protein of unknown function (DUF2888) DUF643 PF04867.12 OWF54573.1 - 0.0059 17.2 0.0 23 5.7 0.0 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF643) Herpes_ICP4_C PF03585.14 OWF54573.1 - 0.028 13.1 0.1 21 3.7 0.0 4.7 2 2 4 7 7 7 0 Herpesvirus ICP4-like protein C-terminal region Peptidase_M36 PF02128.15 OWF54573.1 - 0.061 12.5 0.0 7.5 5.6 0.0 2.5 2 0 0 2 2 2 0 Fungalysin metallopeptidase (M36) DUF3645 PF12359.8 OWF54573.1 - 0.8 9.1 7.3 44 3.6 0.0 6.2 5 2 2 7 7 7 0 Protein of unknown function (DUF3645) ANAPC4_WD40 PF12894.7 OWF54574.1 - 6.1e-12 45.7 21.3 0.17 12.2 0.7 7.3 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Jacalin PF01419.17 OWF54574.1 - 0.00013 21.9 7.4 3.1 7.7 0.1 5.6 1 1 6 7 7 7 2 Jacalin-like lectin domain GvpO PF05800.11 OWF54574.1 - 0.00014 21.7 5.0 7 6.7 0.0 6.8 2 1 3 7 7 7 1 Gas vesicle synthesis protein GvpO SchA_CurD PF04486.12 OWF54574.1 - 0.00015 21.8 3.5 1e+02 3.0 0.0 6.6 2 1 5 8 8 8 0 SchA/CurD like domain Reg_prop PF07494.11 OWF54574.1 - 0.00035 20.4 4.2 4.7e+02 1.6 0.0 10.1 9 6 5 15 15 15 0 Two component regulator propeller Sid-5 PF17204.3 OWF54574.1 - 0.0011 19.1 23.7 75 3.6 0.1 11.5 5 4 8 15 15 15 0 Sid-5 family SH3_9 PF14604.6 OWF54574.1 - 0.016 15.0 0.2 33 4.4 0.0 5.1 4 2 1 6 6 6 0 Variant SH3 domain ANAPC4_WD40 PF12894.7 OWF54575.1 - 1.3e-07 31.8 11.4 0.029 14.7 1.2 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Jacalin PF01419.17 OWF54575.1 - 0.00022 21.1 4.8 0.094 12.7 0.6 3.3 1 1 3 4 4 4 2 Jacalin-like lectin domain SchA_CurD PF04486.12 OWF54575.1 - 0.00041 20.4 1.2 3 8.0 0.1 3.9 1 1 3 4 4 4 1 SchA/CurD like domain Reg_prop PF07494.11 OWF54575.1 - 0.0023 18.0 2.6 4.9e+02 1.6 0.0 7.1 5 3 5 11 11 11 0 Two component regulator propeller P30 PF07390.11 OWF54575.1 - 0.021 14.9 2.7 1.6 8.8 0.1 3.2 1 1 2 3 3 3 0 Mycoplasma P30 protein HTH_39 PF14090.6 OWF54575.1 - 0.083 12.6 2.6 2.4e+02 1.6 0.0 5.5 1 1 6 8 8 8 0 Helix-turn-helix domain DUF4949 PF16307.5 OWF54575.1 - 0.088 12.9 2.6 16 5.6 0.1 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4949) Acetyltransf_10 PF13673.7 OWF54575.1 - 0.2 11.6 3.3 42 4.1 0.0 3.6 1 1 5 6 6 6 0 Acetyltransferase (GNAT) domain GUCT PF08152.12 OWF54575.1 - 0.3 11.4 14.9 3.4 8.0 5.7 3.6 1 1 3 4 4 4 0 GUCT (NUC152) domain Sid-5 PF17204.3 OWF54575.1 - 0.61 10.3 12.4 17 5.7 0.1 6.1 3 1 4 8 8 8 0 Sid-5 family Integrin_B_tail PF07965.12 OWF54575.1 - 0.77 10.3 16.5 0.86 10.1 3.4 3.8 1 1 3 4 4 4 0 Integrin beta tail domain Fer4_21 PF14697.6 OWF54575.1 - 3.3 7.9 15.1 5.5 7.2 1.0 4.0 1 1 4 5 5 5 0 4Fe-4S dicluster domain FLYWCH_N PF15423.6 OWF54575.1 - 4.6 7.4 15.4 8.3 6.6 1.5 4.7 1 1 5 6 6 6 0 FLYWCH-type zinc finger-containing protein AIF-MLS PF14962.6 OWF54575.1 - 7.3 6.5 7.1 9.6 6.1 0.2 3.0 1 1 2 3 3 3 0 Mitochondria Localisation Sequence ANAPC4_WD40 PF12894.7 OWF54576.1 - 1.5e-08 34.8 16.6 0.062 13.6 0.9 4.7 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain SchA_CurD PF04486.12 OWF54576.1 - 1.2e-05 25.4 2.5 2.3 8.4 0.1 4.3 1 1 2 4 4 4 2 SchA/CurD like domain ISP1_C PF18161.1 OWF54576.1 - 1.3e-05 25.2 4.6 0.095 12.7 0.4 4.3 1 1 4 5 5 5 2 ISP1 C-terminal ISP3_C PF18045.1 OWF54576.1 - 6e-05 22.9 10.2 0.21 11.5 1.5 5.2 1 1 4 5 5 5 4 ISP3 C-terminal Jacalin PF01419.17 OWF54576.1 - 0.0017 18.3 7.6 0.3 11.0 0.3 3.9 1 1 2 3 3 3 2 Jacalin-like lectin domain PAXX PF15384.6 OWF54576.1 - 0.06 13.0 13.6 0.58 9.8 2.5 3.0 1 1 1 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 NosD PF05048.13 OWF54576.1 - 0.31 10.3 19.6 1.2 8.3 9.5 2.3 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) PBP_GOBP PF01395.22 OWF54576.1 - 0.68 10.1 11.7 13 6.0 0.3 4.2 2 2 2 4 4 4 0 PBP/GOBP family P30 PF07390.11 OWF54576.1 - 0.87 9.7 10.0 18 5.4 0.9 4.3 1 1 1 4 4 4 0 Mycoplasma P30 protein Integrin_B_tail PF07965.12 OWF54576.1 - 0.88 10.1 10.1 5.7 7.5 1.3 3.4 2 1 2 4 4 4 0 Integrin beta tail domain GUCT PF08152.12 OWF54576.1 - 1.9 8.8 21.9 16 5.9 3.8 4.6 1 1 3 4 4 4 0 GUCT (NUC152) domain Na_H_Exchanger PF00999.21 OWF54577.1 - 9.2e-61 205.7 51.4 1.2e-60 205.3 51.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PHO4 PF01384.20 OWF54577.1 - 0.0021 17.1 1.8 0.0021 17.1 1.8 2.8 1 1 1 2 2 2 1 Phosphate transporter family TMEM154 PF15102.6 OWF54577.1 - 0.089 12.7 1.8 0.23 11.4 0.6 2.1 2 0 0 2 2 2 0 TMEM154 protein family PepSY_TM PF03929.16 OWF54577.1 - 0.21 11.2 2.5 0.21 11.2 0.8 2.0 2 1 0 2 2 2 0 PepSY-associated TM region Saf_2TM PF18303.1 OWF54577.1 - 0.26 10.9 0.0 0.26 10.9 0.0 4.6 5 1 0 5 5 5 0 SAVED-fused 2TM effector domain SPC25 PF06703.11 OWF54577.1 - 6.7 6.5 6.4 0.48 10.2 0.1 2.3 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Mpv17_PMP22 PF04117.12 OWF54578.1 - 1.1e-21 76.8 3.5 1.4e-21 76.5 2.5 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF4573 PF15140.6 OWF54579.1 - 1.8e-11 44.2 35.4 0.0073 16.1 2.5 3.7 2 1 0 3 3 3 3 Domain of unknown function (DUF4573) ThrE PF06738.12 OWF54579.1 - 0.13 11.6 3.7 11 5.2 0.0 4.3 1 1 4 6 6 6 0 Putative threonine/serine exporter CP2 PF04516.15 OWF54580.1 - 5.9e-54 182.8 0.3 1.1e-53 181.9 0.3 1.4 1 0 0 1 1 1 1 CP2 transcription factor Pkinase_Tyr PF07714.17 OWF54581.1 - 1.2e-91 306.6 0.0 2e-91 305.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.13 OWF54581.1 - 1e-48 164.7 3.7 2.2e-48 163.6 3.7 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.25 OWF54581.1 - 1.9e-48 165.1 0.0 3.9e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain FERM_N_2 PF18038.1 OWF54581.1 - 1.7e-23 83.3 1.2 6e-23 81.5 0.1 2.6 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 OWF54581.1 - 1e-10 42.0 1.3 4e-10 40.1 1.3 2.1 1 0 0 1 1 1 1 FERM central domain FERM_F2 PF18377.1 OWF54581.1 - 8.1e-05 22.6 1.0 0.00022 21.2 1.0 1.7 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain Haspin_kinase PF12330.8 OWF54581.1 - 0.0001 21.4 0.3 0.00027 20.0 0.3 1.6 1 0 0 1 1 1 1 Haspin like kinase domain FERM_f0 PF16511.5 OWF54581.1 - 0.0025 18.1 0.0 0.0084 16.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Kinase-like PF14531.6 OWF54581.1 - 0.003 16.9 0.1 0.0083 15.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF4726 PF15855.5 OWF54581.1 - 0.055 13.7 0.2 0.055 13.7 0.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4726) DUF3306 PF11748.8 OWF54581.1 - 0.17 12.8 0.1 0.17 12.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF4663 PF15668.5 OWF54581.1 - 0.58 9.2 5.3 1.1 8.2 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) COX5B PF01215.19 OWF54582.1 - 3.1e-12 46.3 0.1 5.2e-12 45.6 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Vb Terpene_synth_C PF03936.16 OWF54583.1 - 0.035 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain U5_2-snRNA_bdg PF10597.9 OWF54583.1 - 0.1 12.7 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 Trypsin PF00089.26 OWF54584.1 - 4e-54 183.7 3.9 7.4e-28 97.9 0.0 2.6 3 0 0 3 3 3 2 Trypsin Mucin PF01456.17 OWF54584.1 - 4.9e-07 29.8 28.4 9.4e-07 28.9 28.4 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Trypsin_2 PF13365.6 OWF54584.1 - 7e-06 27.0 0.1 0.0058 17.5 0.0 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain DUF1986 PF09342.11 OWF54584.1 - 3.9e-05 24.0 0.1 6.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Sa_NUDIX PF18167.1 OWF54584.1 - 0.048 13.5 1.1 0.085 12.7 1.1 1.3 1 0 0 1 1 1 0 SMODS-associated NUDIX domain Patatin PF01734.22 OWF54584.1 - 3.4 7.8 6.0 6.5 6.9 6.0 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase TPR_8 PF13181.6 OWF54585.1 - 8.1e-08 31.9 0.2 0.015 15.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF54585.1 - 3.5e-06 26.7 0.3 0.53 10.5 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OWF54585.1 - 4.5e-05 23.1 0.1 0.14 12.1 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF54585.1 - 0.057 13.8 0.1 11 6.7 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OWF54585.1 - 0.086 13.0 0.0 8.7 6.6 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF54585.1 - 0.11 12.9 0.2 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OWF54585.1 - 0.13 12.3 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OWF54585.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF2678 PF10856.8 OWF54586.1 - 1.7e-33 115.1 1.1 2e-33 114.8 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF3096 PF11295.8 OWF54586.1 - 0.028 14.1 0.2 0.053 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) Acetyltransf_1 PF00583.25 OWF54587.1 - 3.3e-16 59.6 0.0 5.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF54587.1 - 1.2e-11 44.6 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF54587.1 - 1.7e-09 38.0 0.0 2.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF54587.1 - 1.3e-07 31.5 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OWF54587.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OWF54587.1 - 0.0066 15.9 1.4 0.014 14.9 1.4 1.7 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 OWF54587.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 OWF54587.1 - 0.036 14.7 0.0 0.053 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 OWF54587.1 - 0.036 13.8 0.0 0.092 12.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ BicD PF09730.9 OWF54588.1 - 1.1e-186 622.5 79.3 1.1e-186 622.5 79.3 3.0 1 1 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF3618 PF12277.8 OWF54588.1 - 0.079 13.2 1.0 0.56 10.5 1.0 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) ZapB PF06005.12 OWF54588.1 - 0.084 13.3 0.4 0.084 13.3 0.4 10.7 6 3 1 7 7 7 0 Cell division protein ZapB RACo_linker PF17650.1 OWF54588.1 - 0.086 12.7 4.7 1.5 8.7 0.2 3.4 2 1 1 3 3 3 0 RACo linker region DUF1796 PF08795.10 OWF54588.1 - 0.45 10.5 6.4 1.1 9.1 0.3 3.2 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) SelK_SelG PF10961.8 OWF54588.1 - 0.81 10.3 4.9 2.7 8.7 4.9 1.9 1 0 0 1 1 1 0 Selenoprotein SelK_SelG TSGA13 PF14994.6 OWF54589.1 - 5e-29 101.5 0.2 1.1e-27 97.1 0.2 2.2 1 1 0 1 1 1 1 Testis-specific gene 13 protein G6PD_C PF02781.16 OWF54590.1 - 1.9e-116 388.3 0.0 2.9e-116 387.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OWF54590.1 - 8.3e-61 205.7 0.0 1.3e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain SET PF00856.28 OWF54591.1 - 1.1e-05 25.9 0.3 2.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 SET domain zf_PR_Knuckle PF18445.1 OWF54591.1 - 4.8e-05 23.1 0.3 0.0001 22.0 0.3 1.5 1 0 0 1 1 1 1 PR zinc knuckle motif PIG-X PF08320.12 OWF54591.1 - 0.091 12.7 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 PIG-X / PBN1 ARPC4 PF05856.12 OWF54592.1 - 6.9e-81 269.8 6.9 8e-81 269.6 6.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 OWF54592.1 - 0.0072 16.5 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Sm_like domain Mito_carr PF00153.27 OWF54593.1 - 1.6e-50 168.9 0.1 9.6e-24 83.1 0.1 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein UCH PF00443.29 OWF54594.1 - 1.4e-76 257.4 2.3 2.4e-76 256.6 2.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 OWF54594.1 - 4.7e-32 109.8 1.5 1e-31 108.7 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain DUSP PF06337.12 OWF54594.1 - 9.3e-21 74.3 0.4 9.3e-21 74.3 0.4 2.5 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OWF54594.1 - 4.8e-12 46.1 8.5 9.7e-08 32.0 0.1 3.8 3 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OWF54594.1 - 5.8e-11 42.5 5.0 6.4e-10 39.1 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 OWF54594.1 - 5.9e-07 29.1 1.2 0.0003 20.2 0.2 2.5 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 zf-ribbon_3 PF13248.6 OWF54594.1 - 0.38 10.2 4.6 3.3 7.3 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Aldo_ket_red PF00248.21 OWF54596.1 - 1.9e-47 161.9 0.0 2.3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 OWF54598.1 - 4.2e-62 206.1 0.3 2.3e-20 72.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 OWF54598.1 - 0.89 9.7 2.9 2.9 8.0 0.1 2.8 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Patatin PF01734.22 OWF54599.1 - 2.8e-14 53.8 0.0 5.8e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase dTDP_sugar_isom PF00908.17 OWF54599.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase C2 PF00168.30 OWF54600.1 - 5.9e-30 103.6 0.0 7.2e-15 55.2 0.0 2.9 2 1 0 2 2 2 2 C2 domain RasGAP PF00616.19 OWF54600.1 - 7.6e-27 94.4 0.0 1.3e-15 57.7 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 OWF54600.1 - 5.5e-14 52.5 0.2 1.9e-13 50.8 0.2 2.0 1 0 0 1 1 1 1 PH domain BTK PF00779.19 OWF54600.1 - 1.1e-12 47.5 0.8 2.1e-12 46.6 0.8 1.5 1 0 0 1 1 1 1 BTK motif eIF2A PF08662.11 OWF54601.1 - 1.4e-33 116.4 0.4 1.5e-31 109.8 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OWF54601.1 - 0.0032 17.7 0.2 0.24 11.7 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF54602.1 - 1.7e-28 99.9 0.0 2.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A SR-25 PF10500.9 OWF54602.1 - 0.0076 15.9 10.0 0.011 15.4 10.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Mcm10 PF09332.11 OWF54602.1 - 0.07 12.5 10.5 0.096 12.1 10.5 1.1 1 0 0 1 1 1 0 Mcm10 replication factor SIR4_SID PF16991.5 OWF54602.1 - 0.59 10.2 3.8 0.89 9.6 3.8 1.2 1 0 0 1 1 1 0 Sir4 SID domain DUF4551 PF15087.6 OWF54602.1 - 2.1 7.1 5.8 2.6 6.8 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Paramyxo_ncap PF00973.19 OWF54602.1 - 6.2 5.6 6.1 8.4 5.2 6.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DnaJ PF00226.31 OWF54603.1 - 7e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 OWF54603.1 - 0.00043 20.3 0.0 0.00043 20.3 0.0 1.1 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.6 OWF54603.1 - 7.7 6.2 8.5 1.5 8.5 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) tRNA-synt_1c PF00749.21 OWF54604.1 - 1.4e-95 319.9 0.0 1.9e-95 319.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DSBA PF01323.20 OWF54605.1 - 3.2e-19 69.5 0.0 3.7e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 OWF54605.1 - 7.9e-06 26.1 0.0 1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 OWF54605.1 - 0.053 13.6 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain DUF2310 PF10071.9 OWF54605.1 - 0.18 11.0 0.1 0.45 9.8 0.1 1.6 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) EGF PF00008.27 OWF54606.1 - 0 1389.1 1009.7 2.4e-09 37.3 8.1 66.6 66 0 0 66 66 66 66 EGF-like domain EGF_CA PF07645.15 OWF54606.1 - 0 1310.8 1056.2 5.9e-09 36.0 7.8 66.7 57 10 10 67 67 67 65 Calcium-binding EGF domain hEGF PF12661.7 OWF54606.1 - 1.1e-281 901.3 954.3 2.1e-06 28.1 10.1 68.2 66 0 0 66 66 66 66 Human growth factor-like EGF EGF_2 PF07974.13 OWF54606.1 - 1.9e-112 367.2 1188.1 7.1e-05 23.1 11.7 66.5 66 0 0 66 66 66 57 EGF-like domain EGF_3 PF12947.7 OWF54606.1 - 2e-69 229.5 892.7 9.9e-05 22.5 6.3 67.7 60 8 7 67 67 67 56 EGF domain FXa_inhibition PF14670.6 OWF54606.1 - 2.4e-50 168.5 888.6 0.0014 18.9 5.8 66.8 11 10 55 66 66 66 37 Coagulation Factor Xa inhibitory site SEA PF01390.20 OWF54606.1 - 4.9e-50 168.0 16.4 2.2e-07 30.9 0.0 8.3 8 0 0 8 8 8 8 SEA domain cEGF PF12662.7 OWF54606.1 - 0.00026 20.9 0.5 0.00026 20.9 0.5 66.4 67 2 0 67 67 67 30 Complement Clr-like EGF-like LRR_8 PF13855.6 OWF54607.1 - 2.1e-71 235.6 68.5 5e-09 35.8 0.9 13.2 6 3 11 17 17 17 15 Leucine rich repeat LRR_4 PF12799.7 OWF54607.1 - 6.8e-55 182.1 85.6 1.2e-07 31.9 0.1 16.3 8 5 10 19 19 19 17 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF54607.1 - 1.5e-16 60.4 43.5 0.00013 21.5 1.0 8.9 1 1 8 10 10 10 10 Leucine-rich repeat LRR_1 PF00560.33 OWF54607.1 - 3.6e-16 57.2 64.9 4.9 8.1 0.0 23.4 24 3 1 25 25 25 5 Leucine Rich Repeat LRR_6 PF13516.6 OWF54607.1 - 3e-05 23.7 87.4 3.5 7.9 0.0 21.6 26 0 0 26 26 26 4 Leucine Rich repeat NosD PF05048.13 OWF54607.1 - 0.00056 19.2 5.3 0.015 14.6 0.3 3.1 2 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) Kelch_6 PF13964.6 OWF54607.1 - 0.14 12.5 0.0 17 5.9 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Beta_helix PF13229.6 OWF54607.1 - 6.7 6.5 8.1 25 4.7 0.1 4.1 4 1 1 5 5 5 0 Right handed beta helix region INT_SG_DDX_CT_C PF15300.6 OWF54609.1 - 5.4e-26 90.2 0.3 1.4e-25 88.9 0.3 1.7 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 OWF54609.1 - 1.9e-16 60.6 0.0 6.7e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain PHR PF08005.12 OWF54610.1 - 5.2e-14 53.2 2.4 7.6e-13 49.4 1.0 2.2 2 0 0 2 2 2 1 PHR domain BACK PF07707.15 OWF54610.1 - 3.2e-11 43.2 0.2 1.2e-10 41.3 0.2 2.0 1 1 0 1 1 1 1 BTB And C-terminal Kelch DUF4082 PF13313.6 OWF54610.1 - 9e-05 22.6 0.1 0.0002 21.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4082) BTB PF00651.31 OWF54611.1 - 3.6e-15 56.1 0.0 4.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain zf-P11 PF03854.14 OWF54611.1 - 0.065 12.9 1.0 0.097 12.3 0.9 1.5 1 1 0 1 1 1 0 P-11 zinc finger PHR PF08005.12 OWF54612.1 - 5.1e-13 49.9 0.2 6.3e-13 49.7 0.2 1.0 1 0 0 1 1 1 1 PHR domain DUF4082 PF13313.6 OWF54612.1 - 0.00046 20.3 0.0 0.00062 19.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4082) DUF2334 PF10096.9 OWF54612.1 - 0.083 12.5 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) BTB PF00651.31 OWF54613.1 - 2.2e-14 53.6 1.8 3e-13 50.0 0.1 2.6 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 OWF54613.1 - 4.7e-12 45.9 1.0 1.6e-10 41.0 0.3 3.1 2 2 1 3 3 3 1 BTB And C-terminal Kelch AAA_22 PF13401.6 OWF54614.1 - 5.9e-07 29.8 0.0 3e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OWF54614.1 - 2.3e-06 27.0 0.1 0.076 12.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 OWF54614.1 - 4.9e-06 27.0 0.0 1.6e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_35 PF14516.6 OWF54614.1 - 5.5e-06 25.4 0.1 2.3e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 AAA-like domain ATPase_2 PF01637.18 OWF54614.1 - 0.00021 21.3 0.1 0.00042 20.3 0.1 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OWF54614.1 - 0.0059 17.0 0.2 0.28 11.6 0.0 3.5 3 1 0 3 3 2 1 RNA helicase NACHT PF05729.12 OWF54614.1 - 0.008 16.1 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 OWF54614.1 - 0.0097 15.9 1.6 0.12 12.4 1.6 2.5 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 OWF54614.1 - 0.017 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Torsin PF06309.11 OWF54614.1 - 0.053 13.6 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 Torsin ATPase PF06745.13 OWF54614.1 - 0.08 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 KaiC Ras PF00071.22 OWF54614.1 - 0.081 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Ras family PRK PF00485.18 OWF54614.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 OWF54614.1 - 0.094 12.2 0.1 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Tn7_Tnp_TnsA_C PF08721.11 OWF54614.1 - 0.22 12.2 1.0 26 5.5 0.1 3.0 2 0 0 2 2 2 0 TnsA endonuclease C terminal ABC_tran PF00005.27 OWF54614.1 - 0.59 10.6 0.0 0.59 10.6 0.0 3.6 4 1 0 4 4 4 0 ABC transporter Prefoldin PF02996.17 OWF54616.1 - 9.5e-35 119.1 0.4 1.5e-34 118.5 0.1 1.4 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 OWF54616.1 - 0.0011 18.9 1.1 0.038 13.9 0.0 2.5 2 1 0 2 2 2 1 Prefoldin subunit DUF3627 PF12299.8 OWF54616.1 - 0.018 15.1 1.9 0.023 14.8 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) End3 PF12761.7 OWF54616.1 - 0.022 15.0 6.0 0.25 11.5 6.0 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF1664 PF07889.12 OWF54616.1 - 0.089 12.8 1.5 3.8 7.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cullin PF00888.22 OWF54617.1 - 1.6e-193 644.8 10.2 2.1e-193 644.4 10.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OWF54617.1 - 3.7e-18 65.3 4.4 9.4e-18 64.0 4.4 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Stork_head PF10264.9 OWF54617.1 - 0.04 14.1 0.4 0.13 12.5 0.4 1.9 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain RNA_pol_Rpb6 PF01192.22 OWF54618.1 - 9.8e-16 57.4 0.1 1.6e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 SAPS PF04499.15 OWF54619.1 - 1.1e-84 284.9 10.4 7.1e-52 176.8 1.3 4.3 2 2 1 4 4 4 2 SIT4 phosphatase-associated protein HEAT PF02985.22 OWF54619.1 - 0.0044 17.2 0.6 1.6 9.2 0.1 2.8 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 OWF54619.1 - 0.0051 17.2 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 HEAT repeats FAM60A PF15396.6 OWF54620.1 - 4.3e-82 275.2 6.8 4.3e-82 275.2 6.8 1.7 1 1 1 2 2 2 1 Protein Family FAM60A TPR_12 PF13424.6 OWF54624.1 - 1.2e-48 163.2 17.1 1.5e-09 38.0 1.0 9.8 6 1 5 11 11 11 8 Tetratricopeptide repeat TPR_10 PF13374.6 OWF54624.1 - 1.6e-25 88.2 9.6 0.0016 18.3 0.0 11.1 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 OWF54624.1 - 2.7e-23 80.8 24.8 0.00021 21.0 0.1 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 OWF54624.1 - 4.7e-21 73.2 23.5 0.13 12.4 0.1 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 OWF54624.1 - 6.3e-17 60.3 21.0 0.051 13.8 0.0 10.2 10 0 0 10 10 9 6 Tetratricopeptide repeat NB-ARC PF00931.22 OWF54624.1 - 2.1e-13 50.1 0.2 2.4e-07 30.2 0.0 3.0 2 1 1 3 3 3 2 NB-ARC domain TPR_7 PF13176.6 OWF54624.1 - 2.4e-10 39.7 12.0 0.65 10.2 0.1 10.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF54624.1 - 3.7e-06 27.0 1.7 0.2 12.1 0.0 5.7 6 0 0 6 6 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 OWF54624.1 - 3.7e-06 27.2 0.1 0.00011 22.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain TPR_19 PF14559.6 OWF54624.1 - 6.9e-06 26.5 5.1 3.1 8.4 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat DUF3856 PF12968.7 OWF54624.1 - 0.00028 21.0 2.0 0.64 10.1 0.0 5.1 2 2 5 7 7 7 1 Domain of Unknown Function (DUF3856) AAA_16 PF13191.6 OWF54624.1 - 0.00045 20.7 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_14 PF13428.6 OWF54624.1 - 0.00094 19.8 2.0 28 5.9 0.1 7.2 8 1 0 8 8 6 0 Tetratricopeptide repeat AAA_14 PF13173.6 OWF54624.1 - 0.0011 19.0 1.6 0.0063 16.5 0.2 2.8 2 1 0 2 2 2 1 AAA domain RPN7 PF10602.9 OWF54624.1 - 0.0013 18.4 0.3 0.0013 18.4 0.3 3.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 DUF5113 PF17140.4 OWF54624.1 - 0.0061 16.4 12.1 2.6 7.8 0.0 5.9 4 3 1 5 5 5 2 Domain of unknown function (DUF5113) TPR_6 PF13174.6 OWF54624.1 - 0.012 16.2 14.2 8.1 7.3 0.0 8.2 10 0 0 10 10 7 0 Tetratricopeptide repeat DUF627 PF04781.12 OWF54624.1 - 0.042 13.9 0.8 65 3.6 0.0 5.2 5 1 0 5 5 5 0 Protein of unknown function (DUF627) SPO22 PF08631.10 OWF54624.1 - 0.43 10.0 16.8 0.42 10.1 0.4 6.2 5 1 2 7 7 7 0 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 OWF54624.1 - 1.3 9.8 8.7 26 5.5 1.1 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF54625.1 - 2.4e-20 72.6 2.6 2.5e-09 37.3 0.1 4.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 OWF54625.1 - 1.2e-13 50.4 0.5 9.4e-06 25.3 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OWF54625.1 - 4.8e-11 42.0 5.1 2e-06 27.3 0.3 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF54625.1 - 4.5e-09 35.7 0.9 0.0044 17.0 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 OWF54625.1 - 5.2e-09 35.7 0.3 1.1e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 OWF54625.1 - 8.1e-08 31.9 0.5 0.022 14.9 0.1 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OWF54625.1 - 2.4e-07 30.4 11.2 3.1e-05 23.7 0.2 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat ATPase_2 PF01637.18 OWF54625.1 - 4.9e-07 29.9 0.5 2e-06 27.9 0.1 2.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OWF54625.1 - 8.9e-05 22.9 0.0 0.00041 20.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF54625.1 - 0.00017 21.8 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.6 OWF54625.1 - 0.00021 21.9 0.1 22 6.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF54625.1 - 0.00047 19.6 0.4 0.02 14.3 0.0 2.7 1 1 1 2 2 2 1 MalT-like TPR region AAA_14 PF13173.6 OWF54625.1 - 0.0021 18.1 0.0 0.0065 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_15 PF13429.6 OWF54625.1 - 0.0021 17.3 0.0 2.3 7.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OWF54625.1 - 0.0059 16.3 3.9 1.4 8.6 0.1 3.6 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 OWF54625.1 - 0.018 15.7 3.3 1.4 9.7 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 OWF54625.1 - 0.029 14.4 0.1 6 6.9 0.0 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 OWF54625.1 - 0.03 14.9 0.0 3.7 8.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF54625.1 - 0.042 14.3 0.2 8.5 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OWF54625.1 - 0.092 13.2 0.4 2.2 8.9 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 OWF54625.1 - 0.1 12.4 3.6 0.64 9.8 0.2 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) p450 PF00067.22 OWF54626.1 - 2.3e-86 290.4 0.1 2.8e-86 290.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Anoctamin PF04547.12 OWF54627.1 - 1.5e-155 518.5 12.3 1.8e-155 518.2 12.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OWF54627.1 - 3.2e-66 223.3 0.6 5.1e-66 222.6 0.6 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Gtr1_RagA PF04670.12 OWF54629.1 - 4.1e-68 229.2 2.4 5.3e-68 228.8 2.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OWF54629.1 - 6.3e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF54629.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OWF54629.1 - 3.5e-05 23.3 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF54629.1 - 0.0001 22.3 0.1 0.00026 21.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 OWF54629.1 - 0.0009 18.9 0.2 0.0017 18.0 0.1 1.5 2 0 0 2 2 2 1 Ras family AAA_14 PF13173.6 OWF54629.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OWF54629.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CUB PF00431.20 OWF54631.1 - 0.00041 20.7 0.0 0.0015 18.8 0.0 2.1 2 0 0 2 2 2 1 CUB domain FXa_inhibition PF14670.6 OWF54632.1 - 6.8e-21 74.3 46.9 9.7e-10 38.6 6.3 4.1 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 OWF54632.1 - 1.3e-14 54.4 5.8 0.0029 18.0 0.0 8.2 9 0 0 9 9 8 4 Low-density lipoprotein receptor repeat class B SGL PF08450.12 OWF54632.1 - 0.0027 17.3 3.3 12 5.4 0.0 5.1 3 3 0 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 OWF54632.1 - 0.0037 17.2 1.2 0.0037 17.2 1.2 4.6 4 0 0 4 4 4 2 Complement Clr-like EGF-like RCR PF12273.8 OWF54632.1 - 0.011 16.4 0.3 0.022 15.4 0.3 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 OWF54632.1 - 0.011 16.6 0.1 0.023 15.6 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 OWF54632.1 - 0.028 15.2 0.3 0.075 13.8 0.3 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DAP10 PF07213.11 OWF54632.1 - 0.061 13.3 0.2 0.21 11.6 0.2 1.9 1 0 0 1 1 1 0 DAP10 membrane protein She9_MDM33 PF05546.11 OWF54632.1 - 0.066 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family EGF PF00008.27 OWF54632.1 - 0.25 11.7 31.0 0.1 12.9 5.4 3.9 3 0 0 3 3 3 0 EGF-like domain MAP17 PF15807.5 OWF54632.1 - 0.41 10.9 1.5 0.52 10.5 0.1 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LIM PF00412.22 OWF54635.1 - 4.2e-35 119.7 15.3 9.8e-19 67.3 1.5 2.2 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 OWF54635.1 - 2.6e-21 75.2 1.6 4.4e-21 74.5 1.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF54635.1 - 0.00023 21.0 0.0 0.0006 19.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain C1_1 PF00130.22 OWF54635.1 - 0.11 12.4 12.9 0.2 11.6 4.9 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Furin-like_2 PF15913.5 OWF54635.1 - 2.9 8.1 12.5 0.35 11.0 7.8 1.8 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich FMO-like PF00743.19 OWF54636.1 - 6.1e-204 678.3 0.2 6.7e-204 678.2 0.2 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF54636.1 - 1.5e-19 70.4 0.1 1.1e-14 54.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF54636.1 - 4.1e-15 55.8 0.0 6e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF54636.1 - 1.7e-09 37.3 2.0 3.6e-08 32.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OWF54636.1 - 0.0001 22.8 0.4 0.091 13.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF54636.1 - 0.00025 21.2 0.7 0.00051 20.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain IlvN PF07991.12 OWF54636.1 - 0.015 14.9 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 OWF54636.1 - 0.019 14.9 0.6 20 5.1 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.17 OWF54636.1 - 0.02 14.1 0.7 4.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OWF54636.1 - 0.044 12.9 0.4 1.6 7.7 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF54636.1 - 0.12 11.6 0.4 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OWF54636.1 - 0.17 11.5 0.3 5.8 6.4 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Carn_acyltransf PF00755.20 OWF54638.1 - 3.7e-198 659.9 0.0 4.2e-198 659.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Guanylate_cyc PF00211.20 OWF54640.1 - 3.7e-61 205.9 0.5 1.7e-33 115.8 0.1 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF54640.1 - 1.2e-40 139.4 0.0 1.8e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 OWF54640.1 - 3e-39 135.1 0.1 4e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.25 OWF54640.1 - 8e-34 117.2 0.0 1.2e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF54640.1 - 0.00018 21.0 0.2 0.00028 20.4 0.2 1.3 1 0 0 1 1 1 1 Heme NO binding associated Kinase-like PF14531.6 OWF54640.1 - 0.15 11.4 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Sec1 PF00995.23 OWF54641.1 - 1e-12 48.1 1.3 8e-08 32.0 0.2 2.2 2 0 0 2 2 2 2 Sec1 family Beta-lactamase PF00144.24 OWF54642.1 - 2.2e-14 53.5 0.0 3.6e-14 52.7 0.0 1.2 1 1 0 1 1 1 1 Beta-lactamase GST_N_4 PF17172.4 OWF54643.1 - 3.4e-25 88.7 0.0 4.8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF54643.1 - 7e-19 67.4 0.1 1.1e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF54643.1 - 7e-08 32.8 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 OWF54643.1 - 1.4e-05 25.0 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF54643.1 - 0.00023 21.3 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF54643.1 - 0.001 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF54643.1 - 0.0078 16.6 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF54643.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF54644.1 - 1.6e-25 89.7 0.0 3.8e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF54644.1 - 2.2e-17 62.6 0.0 3.4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF54644.1 - 3.2e-07 30.7 0.0 1.1e-06 29.0 0.0 1.8 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 OWF54644.1 - 0.00018 21.4 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF54644.1 - 0.00033 20.8 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF54644.1 - 0.0094 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF54644.1 - 0.023 15.1 0.0 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF54645.1 - 5.2e-25 88.1 0.0 7.8e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF54645.1 - 1.7e-18 66.1 0.0 2.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF54645.1 - 2.5e-06 27.8 0.0 5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 OWF54645.1 - 4.3e-05 23.4 0.0 7.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF54645.1 - 0.00032 20.9 0.0 0.00071 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF54645.1 - 0.0035 17.5 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF54645.1 - 0.027 14.9 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF54645.1 - 0.16 12.3 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain p450 PF00067.22 OWF54646.1 - 1.3e-77 261.6 0.1 1.5e-77 261.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Uricase PF01014.18 OWF54647.1 - 1.9e-61 206.1 0.4 3.1e-34 118.1 0.1 2.1 2 0 0 2 2 2 2 Uricase Snapin_Pallidin PF14712.6 OWF54648.1 - 6.2e-27 93.9 2.0 7.7e-27 93.5 2.0 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Laminin_II PF06009.12 OWF54648.1 - 0.0029 17.6 3.2 0.0056 16.7 3.2 1.5 1 1 0 1 1 1 1 Laminin Domain II Flagellar_rod PF05149.12 OWF54648.1 - 0.0047 16.4 2.3 0.0063 16.0 2.3 1.2 1 0 0 1 1 1 1 Paraflagellar rod protein FlaC_arch PF05377.11 OWF54648.1 - 0.0066 16.8 3.3 0.62 10.5 0.2 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Fmp27_WPPW PF10359.9 OWF54648.1 - 0.014 14.2 1.2 0.018 13.9 1.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-H PF05837.12 OWF54648.1 - 0.017 15.5 1.1 0.034 14.5 1.1 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) XhlA PF10779.9 OWF54648.1 - 0.026 14.7 4.0 0.13 12.5 0.5 2.3 2 0 0 2 2 2 0 Haemolysin XhlA TRPM_tetra PF16519.5 OWF54648.1 - 0.028 14.5 2.8 1.9 8.6 0.5 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Eisosome1 PF12757.7 OWF54648.1 - 0.03 14.6 1.9 0.097 12.9 0.2 2.1 2 0 0 2 2 2 0 Eisosome protein 1 Apolipoprotein PF01442.18 OWF54648.1 - 0.039 13.8 2.3 0.053 13.4 2.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OWF54648.1 - 0.043 13.9 1.1 0.071 13.2 1.1 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF445 PF04286.12 OWF54648.1 - 0.072 12.9 0.6 0.085 12.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF16 PF01519.16 OWF54648.1 - 0.082 13.4 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 BsuBI_PstI_RE_N PF17728.1 OWF54648.1 - 0.087 12.7 0.1 0.13 12.2 0.1 1.3 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain DUF4665 PF15679.5 OWF54648.1 - 0.088 13.4 3.6 0.15 12.7 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Prefoldin PF02996.17 OWF54648.1 - 0.14 12.1 2.2 0.61 10.0 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 OWF54648.1 - 0.16 12.0 2.2 0.28 11.2 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Latarcin PF10279.9 OWF54648.1 - 0.26 11.7 3.8 2.4 8.6 1.5 2.2 1 1 1 2 2 2 0 Latarcin precursor Tweety PF04906.13 OWF54648.1 - 0.26 9.9 0.6 0.32 9.6 0.6 1.1 1 0 0 1 1 1 0 Tweety Spc7 PF08317.11 OWF54648.1 - 0.34 9.8 4.3 4.2 6.2 0.6 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 OWF54648.1 - 1.1 9.7 6.6 39 4.8 6.6 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GPI2 PF06432.11 OWF54649.1 - 1.3e-65 221.7 6.7 1.4e-65 221.5 6.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PaaX_C PF08223.11 OWF54649.1 - 0.034 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain CcmD PF04995.14 OWF54649.1 - 5.9 7.1 7.3 6.3 7.0 0.1 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) PAP2_C PF14360.6 OWF54649.1 - 9.6 6.8 10.8 3 8.4 3.9 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Shugoshin_N PF07558.11 OWF54650.1 - 1.7 8.6 8.0 1.1 9.1 1.1 3.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Rootletin PF15035.6 OWF54650.1 - 5.3 7.0 56.0 0.019 15.0 12.6 3.2 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion RepL PF05732.11 OWF54651.1 - 0.19 11.1 1.3 1.2e+02 2.1 0.0 4.0 3 0 0 3 3 3 0 Firmicute plasmid replication protein (RepL) Propeptide_C25 PF08126.11 OWF54651.1 - 1.3 8.1 10.1 3 6.9 1.2 2.9 1 1 2 3 3 3 0 Propeptide_C25 F-box-like PF12937.7 OWF54653.1 - 2.1e-14 53.1 3.9 4.1e-14 52.2 3.9 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 OWF54653.1 - 1.1e-13 51.4 7.4 1.2e-05 25.9 0.2 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box PF00646.33 OWF54653.1 - 1.2e-10 41.0 0.9 3e-10 39.7 0.9 1.8 1 0 0 1 1 1 1 F-box domain Ge1_WD40 PF16529.5 OWF54653.1 - 0.0038 16.2 0.0 0.2 10.6 0.0 2.4 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box_4 PF15966.5 OWF54653.1 - 0.027 14.4 0.4 0.061 13.2 0.4 1.6 1 0 0 1 1 1 0 F-box PPI_Ypi1 PF07491.11 OWF54654.1 - 8.2e-22 76.8 7.9 1.8e-21 75.7 7.9 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor Kelch_1 PF01344.25 OWF54655.1 - 1.4e-25 88.6 0.9 4.2e-15 55.0 0.0 3.1 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 OWF54655.1 - 1.5e-20 73.5 0.0 2.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 OWF54655.1 - 1e-13 51.0 0.1 1.8e-06 27.8 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF54655.1 - 1.3e-13 50.7 0.2 8.5e-08 32.2 0.0 3.4 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 OWF54655.1 - 5.6e-11 42.0 2.2 9.9e-06 25.3 0.1 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OWF54655.1 - 5.3e-09 36.1 0.1 4.8e-05 23.5 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain BACK PF07707.15 OWF54655.1 - 4.1e-07 30.0 0.0 8.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF1668 PF07893.13 OWF54655.1 - 0.023 14.1 0.0 0.059 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) Hormone_recep PF00104.30 OWF54657.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Glyco_hydro_18 PF00704.28 OWF54658.1 - 3.3e-27 96.0 0.6 4.4e-27 95.6 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HA2 PF04408.23 OWF54659.1 - 1.3e-20 73.7 0.0 1.3e-20 73.7 0.0 4.3 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OWF54659.1 - 2.3e-19 69.5 0.0 5.9e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OWF54659.1 - 1.3e-14 54.4 0.0 3.6e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OWF54659.1 - 1.1e-06 28.5 0.1 6.2e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OWF54659.1 - 6.2e-05 22.8 0.1 0.00017 21.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OWF54659.1 - 0.00018 20.7 0.0 0.00074 18.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 OWF54659.1 - 0.0012 19.1 0.7 0.0047 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain PWI PF01480.17 OWF54659.1 - 0.0019 18.5 0.0 0.01 16.2 0.1 2.3 2 0 0 2 2 2 1 PWI domain AAA_19 PF13245.6 OWF54659.1 - 0.0076 16.6 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 OWF54659.1 - 0.029 14.3 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 OWF54659.1 - 8.2 6.9 0.0 8.2 6.9 0.0 3.4 2 1 0 2 2 1 0 ABC transporter GDPD PF03009.17 OWF54660.1 - 1.3e-58 198.8 0.0 2.4e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 OWF54660.1 - 0.0091 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Coq4 PF05019.13 OWF54661.1 - 9.6e-93 309.6 0.0 1.1e-92 309.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MFS_1 PF07690.16 OWF54662.1 - 1.5e-31 109.6 38.3 1.9e-24 86.3 11.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF54662.1 - 8.1e-06 25.4 20.4 9.9e-05 21.8 5.4 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4477 PF14780.6 OWF54662.1 - 0.22 11.1 0.1 0.41 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) SRCR PF00530.18 OWF54663.1 - 0 1502.7 137.9 2.7e-31 108.0 0.5 17.7 18 0 0 18 18 18 17 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF54663.1 - 1.2e-79 263.1 48.1 8.5e-05 23.0 0.3 17.7 17 0 0 17 17 17 17 Scavenger receptor cysteine-rich domain Ldl_recept_b PF00058.17 OWF54663.1 - 1.8e-31 108.4 6.0 2.7e-09 37.3 0.2 6.0 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B Hepsin-SRCR PF09272.10 OWF54663.1 - 4.3e-28 98.0 27.6 0.075 13.6 0.0 17.0 18 0 0 18 18 17 8 Hepsin, SRCR domain HYR PF02494.16 OWF54663.1 - 1e-19 70.6 1.4 1.1e-18 67.3 1.8 2.5 2 0 0 2 2 2 1 HYR domain Sushi PF00084.20 OWF54663.1 - 8.6e-14 51.9 23.2 0.00019 21.9 4.4 5.0 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 OWF54663.1 - 3.7e-08 33.5 8.1 3.7e-08 33.5 8.1 4.7 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 OWF54663.1 - 3.8e-05 23.4 2.1 0.048 13.2 0.1 2.8 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF1937 PF09152.10 OWF54663.1 - 0.086 13.7 0.0 35 5.2 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1937) Mid2 PF04478.12 OWF54663.1 - 0.1 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Insulin_TMD PF17870.1 OWF54663.1 - 0.2 11.7 0.1 0.49 10.5 0.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4879 PF16219.5 OWF54663.1 - 3.8 7.7 7.0 0.36 11.0 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4879) Prok-RING_1 PF14446.6 OWF54663.1 - 5.6 7.0 9.3 28 4.7 0.0 6.4 7 0 0 7 7 7 0 Prokaryotic RING finger family 1 Cu2_monoox_C PF03712.15 OWF54665.1 - 1.2e-61 206.8 0.2 1.8e-61 206.2 0.2 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 OWF54665.1 - 4.7e-42 143.3 0.0 8.1e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 OWF54665.1 - 1.9e-21 76.6 0.3 3.4e-21 75.7 0.3 1.4 1 0 0 1 1 1 1 DOMON domain zf-C4 PF00105.18 OWF54666.1 - 3.1e-27 94.8 11.3 6.2e-27 93.9 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF54666.1 - 5.5e-24 84.9 0.4 5.5e-24 84.9 0.4 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Init_tRNA_PT PF04179.12 OWF54666.1 - 0.00063 20.0 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 1 Rit1 DUSP-like domain Tissue_fac PF01108.17 OWF54666.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Tissue factor zf_CopZ PF18423.1 OWF54666.1 - 0.68 9.9 3.6 0.94 9.5 0.0 3.0 3 0 0 3 3 3 0 Zinc binding domain Kelch_1 PF01344.25 OWF54667.1 - 6.4e-29 99.3 1.1 1.3e-11 43.9 0.1 5.9 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 OWF54667.1 - 4.8e-25 87.9 0.1 9e-25 87.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 OWF54667.1 - 1.2e-24 85.7 0.8 8e-09 35.5 0.0 5.6 3 1 2 5 5 5 5 Kelch motif BACK PF07707.15 OWF54667.1 - 7.7e-23 80.6 2.4 1.1e-22 80.0 0.3 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 OWF54667.1 - 4.6e-20 71.4 0.3 8e-08 32.2 0.0 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF54667.1 - 8.1e-15 54.1 0.5 0.00018 21.3 0.1 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OWF54667.1 - 1.1e-14 54.0 1.1 0.00012 22.0 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OWF54667.1 - 3.6e-12 46.3 0.1 0.0011 19.2 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF3342 PF11822.8 OWF54667.1 - 0.005 17.0 0.3 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) FliO PF04347.13 OWF54667.1 - 0.15 12.3 0.0 24 5.3 0.0 2.8 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO Tetraspanin PF00335.20 OWF54668.1 - 8.7e-19 68.1 68.1 7.7e-09 35.6 7.4 5.1 4 1 0 4 4 4 3 Tetraspanin family Prominin PF05478.11 OWF54668.1 - 0.16 9.9 9.2 0.43 8.5 9.2 1.7 1 0 0 1 1 1 0 Prominin CAP PF00188.26 OWF54669.1 - 1.5e-15 58.2 0.0 2.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TRH PF05438.12 OWF54670.1 - 8.5e-34 117.2 0.0 3.3e-07 30.3 0.0 10.3 1 1 0 1 1 1 1 Thyrotropin-releasing hormone (TRH) EcoRII-N PF09217.10 OWF54670.1 - 5.5e-31 107.4 0.0 1.1 9.0 0.0 13.8 1 1 26 27 27 27 26 Restriction endonuclease EcoRII, N-terminal RDD PF06271.12 OWF54670.1 - 2.7e-17 63.3 1.1 1.2e+02 2.9 0.0 17.9 1 1 29 30 30 30 0 RDD family G10 PF01125.17 OWF54670.1 - 5.8 6.7 9.2 11 5.7 0.2 4.2 1 1 1 3 3 3 0 G10 protein Sulfotransfer_1 PF00685.27 OWF54671.1 - 1.6e-17 63.9 0.3 4.4e-17 62.5 0.3 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF54671.1 - 1.7e-14 54.8 0.3 7.7e-14 52.6 0.3 1.9 1 1 0 1 1 1 1 Sulfotransferase family zf-RING_UBOX PF13445.6 OWF54673.1 - 7.7e-09 35.4 13.5 2.7e-08 33.7 13.5 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF54673.1 - 5.7e-07 29.3 14.0 5.7e-07 29.3 14.0 3.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF54673.1 - 7.7e-07 29.2 15.0 7.7e-07 29.2 15.0 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OWF54673.1 - 4.5e-06 26.9 12.6 4.5e-06 26.9 12.6 3.4 3 0 0 3 3 2 1 Ring finger domain zf-B_box PF00643.24 OWF54673.1 - 4.5e-05 23.5 8.0 4.5e-05 23.5 8.0 3.5 3 0 0 3 3 2 2 B-box zinc finger zf-RING_5 PF14634.6 OWF54673.1 - 0.00017 21.4 10.8 0.00017 21.4 10.8 3.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF54673.1 - 0.00037 20.3 10.7 0.00037 20.3 10.7 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF54673.1 - 0.0015 18.3 13.8 0.0015 18.3 13.8 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SBBP PF06739.11 OWF54673.1 - 0.0071 16.3 0.1 0.026 14.5 0.0 2.0 2 0 0 2 2 2 1 Beta-propeller repeat zf-RING_11 PF17123.5 OWF54673.1 - 0.035 13.9 4.3 0.16 11.8 4.3 2.3 1 0 0 1 1 1 0 RING-like zinc finger Exonuc_VII_L PF02601.15 OWF54673.1 - 0.07 12.7 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPH PF13868.6 OWF54673.1 - 0.14 10.6 2.0 0.21 10.1 2.0 1.1 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain Tup_N PF08581.10 OWF54673.1 - 0.73 10.2 4.4 1.8 8.9 4.4 1.6 1 0 0 1 1 1 0 Tup N-terminal NHL PF01436.21 OWF54673.1 - 1.4 9.1 3.6 37 4.6 0.1 4.0 4 0 0 4 4 4 0 NHL repeat SSF PF00474.17 OWF54674.1 - 1.1e-129 432.9 17.4 1.6e-129 432.3 17.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Tetraspanin PF00335.20 OWF54675.1 - 5.6e-32 111.3 13.1 6.5e-32 111.1 13.1 1.0 1 0 0 1 1 1 1 Tetraspanin family C2 PF00168.30 OWF54676.1 - 3.6e-43 146.1 0.2 2.7e-21 75.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 OWF54676.1 - 0.00033 20.6 0.2 0.051 13.5 0.0 3.2 3 1 0 3 3 3 1 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 OWF54676.1 - 0.011 15.3 0.2 0.75 9.4 0.1 2.4 1 1 1 2 2 2 0 CEP76 C2 domain DOCK-C2 PF14429.6 OWF54676.1 - 0.064 13.1 0.1 0.83 9.4 0.0 2.4 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins zf-RING_2 PF13639.6 OWF54677.1 - 1.8e-12 47.4 7.4 3e-12 46.7 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OWF54677.1 - 1.9e-07 31.3 6.9 3.5e-07 30.4 6.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OWF54677.1 - 7.1e-07 29.0 7.6 1.1e-06 28.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OWF54677.1 - 7.2e-07 28.8 3.0 7.2e-07 28.8 3.0 2.1 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OWF54677.1 - 5.3e-05 23.2 1.9 8.9e-05 22.5 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OWF54677.1 - 5.4e-05 23.0 8.1 9.5e-05 22.2 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54677.1 - 0.00014 21.8 8.0 0.00023 21.1 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OWF54677.1 - 0.00015 21.5 6.3 0.00025 20.8 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OWF54677.1 - 0.0045 17.1 8.6 0.0082 16.3 8.6 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 OWF54677.1 - 0.04 14.1 5.7 0.09 13.0 5.7 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OWF54677.1 - 0.059 13.4 6.8 0.12 12.4 6.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.11 OWF54677.1 - 0.091 12.8 0.9 0.18 11.8 0.9 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain CCDC50_N PF15295.6 OWF54677.1 - 0.11 12.7 2.6 0.81 9.9 2.8 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Zn_ribbon_17 PF17120.5 OWF54677.1 - 0.5 10.0 6.2 0.88 9.2 6.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OWF54677.1 - 1 9.3 7.7 3.6 7.5 7.7 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF54677.1 - 2.1 8.2 6.8 4.6 7.1 6.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain baeRF_family12 PF18856.1 OWF54677.1 - 4 8.0 9.7 0.95 10.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 zf-RING_2 PF13639.6 OWF54678.1 - 2.9e-14 53.1 7.1 5.3e-14 52.3 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF54678.1 - 7.1e-12 44.8 8.1 7.6e-11 41.6 3.5 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OWF54678.1 - 1.7e-09 37.3 5.7 3.4e-09 36.4 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF54678.1 - 4.1e-09 36.6 4.7 9.9e-09 35.4 4.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OWF54678.1 - 8.5e-09 35.1 4.6 1.3e-08 34.6 4.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF54678.1 - 6.3e-08 32.4 6.1 1.1e-07 31.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54678.1 - 1.3e-07 31.4 4.3 2.1e-07 30.8 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF54678.1 - 4.1e-07 29.9 3.0 5.4e-07 29.5 0.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OWF54678.1 - 3.7e-06 26.7 4.9 5.9e-06 26.0 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OWF54678.1 - 1.7e-05 24.8 0.4 3.7e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OWF54678.1 - 0.0022 17.5 4.8 0.0039 16.8 4.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OWF54678.1 - 0.015 15.4 5.6 0.032 14.3 5.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 OWF54678.1 - 0.022 14.6 2.8 0.04 13.7 2.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 OWF54678.1 - 0.024 14.6 5.8 0.07 13.1 1.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 OWF54678.1 - 0.028 14.6 6.9 0.37 11.0 6.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OWF54678.1 - 0.07 12.9 4.1 0.13 12.1 4.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OWF54678.1 - 0.18 12.0 3.5 0.77 10.0 3.8 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 OWF54678.1 - 0.45 10.7 3.2 0.92 9.7 3.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_10 PF16685.5 OWF54678.1 - 0.74 10.0 4.3 1.6 9.0 4.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 CCDC50_N PF15295.6 OWF54678.1 - 1.4 9.1 13.5 2 8.6 4.9 3.2 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus zf-RING-like PF08746.11 OWF54678.1 - 1.7 9.0 5.0 3.4 8.0 5.0 1.6 1 0 0 1 1 1 0 RING-like domain AMP-binding PF00501.28 OWF54679.1 - 9.3e-68 228.7 0.0 1.1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF54679.1 - 0.0036 18.3 0.1 0.0077 17.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyltransferase PF01553.21 OWF54680.1 - 1.5e-33 115.3 0.0 2.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Nuc_deoxyri_tr2 PF15891.5 OWF54682.1 - 1.5e-40 137.8 0.0 1.9e-21 76.4 0.0 2.3 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like EF-hand_6 PF13405.6 OWF54682.1 - 0.034 14.1 0.0 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 OWF54682.1 - 0.079 12.5 0.0 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 EF hand GHL10 PF02638.15 OWF54682.1 - 0.096 11.8 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Proteasom_PSMB PF10508.9 OWF54683.1 - 3.5e-123 411.8 3.2 3.9e-123 411.6 3.2 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RTTN_N PF14726.6 OWF54683.1 - 0.2 12.4 6.6 2 9.3 0.3 3.7 2 1 2 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning DUF908 PF06012.12 OWF54683.1 - 6.8 6.0 10.8 0.32 10.4 1.4 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF908) DUF4455 PF14643.6 OWF54684.1 - 2.9e-161 537.3 31.3 2.9e-161 537.3 31.3 4.5 3 2 1 4 4 4 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 OWF54684.1 - 2.1e-58 197.5 11.4 2.1e-58 197.5 11.4 6.4 5 1 2 7 7 7 1 Domain of unknown function (DUF4456) DUF4428 PF14471.6 OWF54684.1 - 0.05 13.5 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DED PF01335.21 OWF54684.1 - 3.8 7.9 7.1 6.8 7.1 1.0 4.3 3 0 0 3 3 3 0 Death effector domain AhpC-TSA PF00578.21 OWF54687.1 - 5.1e-28 97.5 0.0 7.2e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OWF54687.1 - 5.1e-15 55.5 0.0 6.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OWF54687.1 - 6e-12 45.2 0.2 1.1e-11 44.4 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 OWF54687.1 - 0.0027 17.8 0.0 0.018 15.2 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme adh_short PF00106.25 OWF54688.1 - 8.5e-52 175.4 2.2 1.1e-51 175.1 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF54688.1 - 7.7e-50 169.6 0.4 9.7e-50 169.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF54688.1 - 1.2e-15 57.9 1.6 2.3e-15 57.0 1.6 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF54688.1 - 0.001 18.6 0.5 0.0021 17.6 0.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OWF54688.1 - 0.0083 16.0 0.1 0.026 14.4 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OWF54688.1 - 0.031 13.4 0.7 0.044 12.9 0.7 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CbiA PF01656.23 OWF54688.1 - 0.033 14.2 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 3Beta_HSD PF01073.19 OWF54688.1 - 0.05 12.6 0.7 0.11 11.5 0.7 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 OWF54688.1 - 0.052 12.9 0.8 0.16 11.3 0.1 2.1 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pept_tRNA_hydro PF01195.19 OWF54689.1 - 1.9e-38 132.1 0.2 3.2e-38 131.4 0.2 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Methyltransf_7 PF03492.15 OWF54690.1 - 1.6e-30 106.5 0.1 1.9e-30 106.2 0.1 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase CD225 PF04505.12 OWF54690.1 - 0.095 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein MORN_2 PF07661.13 OWF54690.1 - 0.13 12.6 0.5 0.7 10.3 0.3 2.2 2 0 0 2 2 2 0 MORN repeat variant GSDH PF07995.11 OWF54691.1 - 7.4e-39 134.0 0.0 1.2e-38 133.3 0.0 1.3 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SRCR PF00530.18 OWF54692.1 - 9.5e-56 186.5 2.7 1.1e-29 102.9 0.5 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 OWF54692.1 - 3.2e-15 56.5 0.1 7.7e-07 29.6 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 OWF54692.1 - 2.3e-13 50.1 0.1 4.9e-06 26.6 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF54692.1 - 3.5e-13 49.7 8.0 0.00048 20.3 0.3 4.8 3 2 2 5 5 5 4 Immunoglobulin V-set domain I-set PF07679.16 OWF54692.1 - 5.1e-11 42.5 0.5 0.00053 20.0 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF54692.1 - 8.1e-09 35.7 0.0 0.0069 16.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain SRCR_2 PF15494.6 OWF54692.1 - 1.2e-08 35.4 3.0 0.0022 18.5 0.1 2.9 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Ig_6 PF18452.1 OWF54692.1 - 0.0047 16.5 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Hepsin-SRCR PF09272.10 OWF54692.1 - 0.014 15.9 0.0 6.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Hepsin, SRCR domain Izumo-Ig PF16706.5 OWF54692.1 - 0.024 14.7 0.1 3.3 7.8 0.0 2.9 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 OWF54692.1 - 0.074 13.4 0.1 1.9 8.9 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin C1-set domain TBPIP_N PF15517.6 OWF54693.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 TBP-interacting protein N-terminus ECR1_N PF14382.6 OWF54694.1 - 1.7e-17 62.9 0.3 3.1e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OWF54694.1 - 7.3e-14 51.9 0.1 1.6e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 OWF54694.1 - 0.0045 17.6 0.9 2.4 8.8 0.0 3.3 2 1 0 3 3 3 2 Exosome component EXOSC1/CSL4 Pkinase_Tyr PF07714.17 OWF54695.1 - 9.6e-97 323.3 0.0 1.6e-96 322.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF54695.1 - 3.5e-47 161.0 0.0 6.8e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 OWF54695.1 - 1.2e-24 86.1 0.5 3.3e-24 84.8 0.5 1.8 1 0 0 1 1 1 1 SH2 domain F_actin_bind PF08919.10 OWF54695.1 - 3.3e-24 85.1 0.0 8.8e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 F-actin binding SH3_1 PF00018.28 OWF54695.1 - 5.5e-11 41.9 0.1 1.2e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OWF54695.1 - 7.8e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 OWF54695.1 - 4.9e-06 26.7 0.8 1.3e-05 25.3 0.8 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.17 OWF54695.1 - 2.7e-05 23.8 0.1 6.7e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 OWF54695.1 - 0.0054 15.7 1.3 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain ecTbetaR2 PF08917.10 OWF54695.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain Ion_trans PF00520.31 OWF54696.1 - 7.8e-07 28.6 25.4 2.9e-06 26.7 24.9 2.0 1 1 1 2 2 2 1 Ion transport protein Ank PF00023.30 OWF54696.1 - 0.00088 19.6 1.2 0.25 11.9 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OWF54696.1 - 0.028 15.0 1.2 0.32 11.6 0.1 2.9 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) TetR_C_9 PF14514.6 OWF54697.1 - 0.0032 17.6 2.7 0.9 9.7 0.2 2.7 1 1 2 3 3 3 2 Tetracyclin repressor-like, C-terminal domain DUF3880 PF12996.7 OWF54697.1 - 0.0097 16.0 4.8 0.038 14.1 0.4 2.4 1 1 1 2 2 2 2 DUF based on E. rectale Gene description (DUF3880) CoA_trans PF01144.23 OWF54698.1 - 0.11 11.9 3.1 12 5.3 0.2 4.6 2 2 1 4 4 4 0 Coenzyme A transferase TetR_C_9 PF14514.6 OWF54698.1 - 0.6 10.3 10.7 3.7 7.7 0.1 3.9 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain LRR_9 PF14580.6 OWF54699.1 - 1.7e-09 37.4 0.1 3.5e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OWF54699.1 - 6.4e-08 32.8 7.7 0.00011 22.5 1.4 2.9 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF54699.1 - 3.7e-07 29.8 2.5 7e-07 28.9 1.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat IQ PF00612.27 OWF54699.1 - 0.00014 21.3 0.9 0.00039 20.0 0.9 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif CheW PF01584.19 OWF54700.1 - 0.00023 20.8 22.5 1.8 8.2 0.6 6.8 1 1 6 8 8 8 7 CheW-like domain OGG_N PF07934.12 OWF54701.1 - 2.6e-30 105.0 0.1 1.1e-29 103.0 0.1 2.0 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OWF54701.1 - 7.5e-16 58.5 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_L15e PF00827.17 OWF54701.1 - 0.0056 16.4 0.2 7.5 6.2 0.0 3.2 3 0 0 3 3 3 1 Ribosomal L15 HHH PF00633.23 OWF54701.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Kinesin PF00225.23 OWF54702.1 - 2.8e-107 358.5 0.2 2.8e-107 358.5 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF54702.1 - 1.6e-20 73.6 0.0 8e-20 71.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 OWF54702.1 - 5.3e-12 46.3 24.0 1.2e-09 38.6 0.9 4.5 2 2 2 4 4 4 2 Kinesin-associated FHA PF00498.26 OWF54702.1 - 5.5e-07 29.8 0.2 1.3e-06 28.7 0.2 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OWF54702.1 - 0.0089 16.3 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 OWF54702.1 - 0.02 15.3 0.3 0.085 13.3 0.3 2.2 1 0 0 1 1 1 0 Kinesin protein 1B Ta0938 PF11494.8 OWF54702.1 - 0.056 13.7 0.0 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Ta0938 YbjQ_1 PF01906.17 OWF54702.1 - 0.37 11.5 2.5 16 6.2 0.3 2.8 2 0 0 2 2 2 0 Putative heavy-metal-binding DUF948 PF06103.11 OWF54702.1 - 3.3 8.0 6.2 3.2 8.1 2.6 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF465 PF04325.13 OWF54702.1 - 3.4 7.8 10.6 4.3 7.4 3.3 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF465) Aldo_ket_red PF00248.21 OWF54703.1 - 6.2e-06 25.6 0.1 9e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family CBFD_NFYB_HMF PF00808.23 OWF54704.1 - 1.7e-20 73.0 0.4 1.7e-20 73.0 0.4 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 OWF54704.1 - 0.0001 22.4 0.2 0.0001 22.4 0.2 1.5 2 0 0 2 2 2 1 CENP-W protein Histone PF00125.24 OWF54704.1 - 0.00018 21.9 0.1 0.00018 21.9 0.1 2.0 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Med25_VWA PF11265.8 OWF54704.1 - 0.036 13.9 0.2 0.063 13.1 0.0 1.4 2 0 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A DUF688 PF05097.12 OWF54704.1 - 0.088 12.0 5.5 0.12 11.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Jnk-SapK_ap_N PF09744.9 OWF54704.1 - 0.89 9.8 14.2 1.7 8.8 14.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.11 OWF54705.1 - 1.3 9.7 6.1 4.2 8.0 2.1 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Goodbye PF17109.5 OWF54705.1 - 4.9 7.6 5.2 3.3 8.2 0.7 2.9 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain EMC3_TMCO1 PF01956.16 OWF54705.1 - 6.8 6.4 8.6 1.1 9.0 4.4 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PNMA PF14893.6 OWF54706.1 - 0.034 13.5 0.6 0.051 13.0 0.6 1.2 1 0 0 1 1 1 0 PNMA Retrotrans_gag PF03732.17 OWF54706.1 - 0.038 14.3 0.9 0.073 13.4 0.3 1.8 1 1 1 2 2 2 0 Retrotransposon gag protein CbiG_mid PF11761.8 OWF54707.1 - 2.7e-17 62.7 11.4 25 5.1 0.0 20.3 1 1 6 7 7 7 1 Cobalamin biosynthesis central region ELYS PF13934.6 OWF54707.1 - 1e-09 38.8 38.2 1.8e+04 -23.3 38.2 8.4 1 1 0 1 1 1 0 Nuclear pore complex assembly DUF3958 PF13125.6 OWF54707.1 - 0.074 13.3 49.6 62 3.9 0.3 11.0 1 1 16 18 18 18 0 Protein of unknown function (DUF3958) Cnd1 PF12717.7 OWF54707.1 - 3.7 7.6 36.9 43 4.1 1.6 6.8 1 1 5 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DHH PF01368.20 OWF54707.1 - 4.1 7.7 61.0 1.8e+04 -51.5 61.0 13.8 1 1 0 1 1 1 0 DHH family SNF2_N PF00176.23 OWF54708.1 - 7.1e-63 212.4 0.7 1.8e-62 211.1 0.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 OWF54708.1 - 5.4e-35 119.9 0.2 5.4e-35 119.9 0.2 4.6 4 0 0 4 4 4 1 CDH1/2 SANT-Helical linker 1 DUF4208 PF13907.6 OWF54708.1 - 1e-26 93.2 0.2 6.7e-26 90.6 0.2 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 OWF54708.1 - 1.6e-24 85.6 7.9 2.6e-15 56.0 0.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 OWF54708.1 - 7.1e-19 68.2 0.0 1.7e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF54708.1 - 2.5e-06 27.6 4.0 2.6e-06 27.5 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 OWF54708.1 - 0.0034 17.6 0.0 0.035 14.3 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.25 OWF54710.1 - 1.3e-72 244.3 0.0 1.6e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF54710.1 - 6.9e-30 104.2 0.0 9.7e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF54710.1 - 1.8e-05 24.3 0.1 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OWF54710.1 - 0.014 14.4 0.1 0.038 12.9 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OWF54710.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 OWF54710.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase IMS PF00817.20 OWF54711.1 - 3.8e-44 150.3 0.0 6.4e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OWF54711.1 - 2.4e-13 50.8 0.2 5.1e-13 49.7 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 OWF54711.1 - 0.00038 19.8 0.7 0.013 15.0 0.8 2.5 2 0 0 2 2 2 1 Ubiquitin binding region Cdd1 PF11731.8 OWF54711.1 - 0.00078 19.6 0.0 0.0066 16.7 0.0 2.5 2 0 0 2 2 2 1 Pathogenicity locus DNA_pol_lambd_f PF10391.9 OWF54711.1 - 0.0054 16.5 0.1 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda IMS_HHH PF11798.8 OWF54711.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif MgtE_N PF03448.17 OWF54711.1 - 0.071 13.7 0.6 15 6.3 0.1 3.2 3 0 0 3 3 3 0 MgtE intracellular N domain Colipase_C PF02740.14 OWF54713.1 - 4.5 7.5 13.6 0.2 11.9 1.1 2.8 3 1 0 3 3 3 0 Colipase, C-terminal domain WSC PF01822.19 OWF54714.1 - 2.5e-07 30.8 10.0 5.5e-07 29.7 5.2 3.7 3 0 0 3 3 3 1 WSC domain Lectin_C PF00059.21 OWF54714.1 - 2.6e-07 31.3 18.2 0.0073 17.0 1.2 4.6 3 2 1 4 4 4 3 Lectin C-type domain Xlink PF00193.17 OWF54714.1 - 0.0029 17.9 1.3 0.52 10.7 0.0 3.2 3 0 0 3 3 3 1 Extracellular link domain Orthoreo_P10 PF07204.11 OWF54714.1 - 0.0058 16.6 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 stn_TNFRSF12A PF12191.8 OWF54714.1 - 0.053 13.7 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Kazal_2 PF07648.15 OWF54714.1 - 0.13 12.4 2.3 27 5.0 1.3 3.1 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DUF4542 PF15075.6 OWF54715.1 - 7e-20 71.8 2.1 1e-11 45.4 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4542) TauD PF02668.16 OWF54716.1 - 5.6e-21 75.5 0.0 9.8e-21 74.7 0.0 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Lectin_C PF00059.21 OWF54716.1 - 0.00071 20.3 0.1 0.0014 19.3 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain DUF2250 PF10007.9 OWF54717.1 - 0.0037 17.3 0.5 1.8 8.7 0.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2250) zf-CCHC PF00098.23 OWF54717.1 - 0.41 10.8 2.1 0.71 10.1 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4542 PF15075.6 OWF54718.1 - 2.1e-50 170.6 0.0 2.6e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) Phosphodiest PF01663.22 OWF54719.1 - 1.3e-75 255.2 0.3 1.6e-75 255.0 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OWF54719.1 - 0.00098 18.6 0.0 0.015 14.7 0.0 2.2 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OWF54719.1 - 0.18 10.3 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) RBD-FIP PF09457.10 OWF54722.1 - 0.0017 18.2 9.5 17 5.4 0.0 8.8 5 4 6 11 11 11 2 FIP domain NAD_binding_8 PF13450.6 OWF54722.1 - 0.25 11.6 10.7 42 4.5 0.5 5.4 1 1 5 6 6 6 0 NAD(P)-binding Rossmann-like domain Transp_inhibit PF18791.1 OWF54723.1 - 0.0012 18.3 16.5 9.7 5.8 0.1 6.2 1 1 6 7 7 7 6 Transport inhibitor response 1 protein domain Crr6 PF08847.11 OWF54723.1 - 8 6.1 22.7 11 5.6 0.1 5.9 1 1 7 8 8 8 0 Chlororespiratory reduction 6 Transp_inhibit PF18791.1 OWF54724.1 - 0.074 12.6 37.6 13 5.3 0.1 10.2 4 4 11 15 15 15 0 Transport inhibitor response 1 protein domain Transp_inhibit PF18791.1 OWF54725.1 - 0.00012 21.5 48.8 7.1 6.2 0.1 12.5 4 4 8 15 15 15 13 Transport inhibitor response 1 protein domain Transp_inhibit PF18791.1 OWF54726.1 - 0.004 16.6 18.5 2.2 7.8 0.1 5.8 3 1 5 8 8 8 8 Transport inhibitor response 1 protein domain IstB_IS21_ATP PF08483.11 OWF54727.1 - 8.7e-09 35.1 87.2 2e+02 2.0 0.0 33.5 37 0 0 37 37 37 0 IstB-like ATP binding N-terminal Fibrinogen_BP PF08017.11 OWF54727.1 - 1.1e-06 27.4 0.0 0.049 12.1 0.0 3.0 1 1 2 3 3 3 3 Fibrinogen binding protein MAM33 PF02330.16 OWF54727.1 - 3.7e-06 27.0 21.1 19 5.1 0.0 9.2 1 1 12 13 13 13 2 Mitochondrial glycoprotein MoaE PF02391.17 OWF54727.1 - 0.00024 21.3 27.6 36 4.7 0.6 11.3 1 1 3 6 6 6 0 MoaE protein OKR_DC_1_C PF03711.15 OWF54727.1 - 0.00053 20.3 22.1 1.3e+02 2.8 0.1 10.5 2 1 11 15 15 15 0 Orn/Lys/Arg decarboxylase, C-terminal domain Cation_efflux PF01545.21 OWF54731.1 - 8.8e-25 87.6 9.1 1.2e-24 87.2 9.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OWF54731.1 - 6.9e-11 42.1 0.7 5e-10 39.4 0.3 2.4 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Arch_flagellin PF01917.16 OWF54732.1 - 0.72 10.0 6.3 1.1 9.4 6.3 1.4 1 1 0 1 1 1 0 Archaebacterial flagellin BNR PF02012.20 OWF54732.1 - 0.89 9.8 7.5 84 3.8 0.0 5.0 6 0 0 6 6 6 0 BNR/Asp-box repeat PNMA PF14893.6 OWF54733.1 - 4.8e-11 42.6 0.2 9.7e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 PNMA zf-CCHC PF00098.23 OWF54733.1 - 4.7e-06 26.4 1.5 9.3e-06 25.5 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Leu_zip PF15294.6 OWF54733.1 - 0.0019 17.8 4.7 0.39 10.2 4.2 2.1 1 1 1 2 2 2 2 Leucine zipper TPR_MLP1_2 PF07926.12 OWF54733.1 - 0.0096 16.0 1.5 0.022 14.8 1.5 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF21 PF01595.20 OWF54733.1 - 0.023 14.4 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain CENP-F_leu_zip PF10473.9 OWF54733.1 - 0.097 12.7 2.2 0.13 12.3 0.6 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 OWF54733.1 - 0.35 11.2 7.2 0.95 9.8 7.2 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PDGF PF00341.17 OWF54734.1 - 5.4e-10 39.4 3.8 5.4e-10 39.4 3.8 2.6 2 1 0 2 2 2 1 PDGF/VEGF domain Mucin PF01456.17 OWF54734.1 - 3.7e-05 23.7 29.2 3.7e-05 23.7 29.2 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein Pex14_N PF04695.13 OWF54734.1 - 0.011 16.4 8.3 0.018 15.7 8.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region INO80_Ies4 PF08193.11 OWF54734.1 - 0.58 10.1 9.1 0.86 9.5 9.1 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Med16 PF11635.8 OWF54735.1 - 4.2e-71 239.9 1.4 7.6e-71 239.1 1.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 OWF54735.1 - 0.00041 20.6 0.1 2 8.7 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OWF54735.1 - 0.13 13.1 0.3 2.3 9.2 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat AAA_33 PF13671.6 OWF54736.1 - 8.4e-15 55.2 0.0 2.7e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain CUE PF02845.16 OWF54736.1 - 1.6e-08 34.1 1.8 0.00093 18.9 0.1 2.8 2 0 0 2 2 2 2 CUE domain AAA_18 PF13238.6 OWF54736.1 - 0.00032 21.3 0.0 0.0022 18.5 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OWF54736.1 - 0.00057 20.3 0.0 0.003 18.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain DUF1296 PF06972.11 OWF54736.1 - 0.0033 17.5 0.1 0.025 14.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) CPT PF07931.12 OWF54736.1 - 0.0035 17.2 0.0 0.036 13.9 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 OWF54736.1 - 0.0087 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin UBA PF00627.31 OWF54736.1 - 0.012 15.4 0.3 0.21 11.5 0.2 2.5 2 0 0 2 2 2 0 UBA/TS-N domain UBA_4 PF14555.6 OWF54736.1 - 0.032 14.0 0.1 0.032 14.0 0.1 2.5 3 0 0 3 3 3 0 UBA-like domain APS_kinase PF01583.20 OWF54736.1 - 0.065 13.1 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_22 PF13401.6 OWF54736.1 - 0.098 12.9 0.0 0.42 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain PAM2 PF07145.15 OWF54736.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Tubulin PF00091.25 OWF54737.1 - 4.1e-67 226.2 0.0 5.4e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OWF54737.1 - 1.1e-51 174.2 0.0 1.7e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OWF54737.1 - 0.00018 21.3 0.2 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 Tubulin domain Ribosomal_S14 PF00253.21 OWF54738.1 - 4.2e-13 48.8 2.2 8.6e-13 47.8 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DZR PF12773.7 OWF54738.1 - 0.022 14.7 1.8 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf-dskA_traR PF01258.17 OWF54738.1 - 0.23 11.4 5.9 9.4 6.3 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger p450 PF00067.22 OWF54739.1 - 1.1e-99 334.3 0.0 2.7e-99 333.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF4041 PF13250.6 OWF54739.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) p450 PF00067.22 OWF54740.1 - 4.4e-102 342.2 0.2 2.8e-101 339.6 0.2 1.8 1 1 0 1 1 1 1 Cytochrome P450 ANAPC4_WD40 PF12894.7 OWF54741.1 - 0.00063 20.0 0.2 0.0046 17.2 0.1 2.4 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C3H2C3 PF17122.5 OWF54741.1 - 0.13 12.3 7.8 0.4 10.8 7.8 1.9 1 0 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 OWF54741.1 - 1.2 9.5 8.4 4.9 7.6 8.4 2.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 OWF54741.1 - 4.9 7.3 7.5 20 5.3 7.5 2.2 1 0 0 1 1 1 0 RING-type zinc-finger Sulfatase PF00884.23 OWF54742.1 - 2.8e-60 204.3 0.9 3.7e-60 203.9 0.9 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF54742.1 - 0.017 14.7 1.0 0.089 12.4 0.0 2.1 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase CnrY PF17524.2 OWF54742.1 - 0.22 11.8 0.4 0.5 10.6 0.4 1.5 1 0 0 1 1 1 0 Anti-sigma factor CnrY Myb_DNA-binding PF00249.31 OWF54743.1 - 4.4e-14 52.4 1.7 1.2e-06 28.6 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF54743.1 - 2.2e-12 47.0 3.3 7.5e-06 26.1 0.3 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Atx10homo_assoc PF09759.9 OWF54743.1 - 3.8e-05 23.7 0.6 3.7 7.6 0.0 4.2 2 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain IBN_N PF03810.19 OWF54743.1 - 0.031 14.2 0.2 1.7 8.6 0.0 3.4 2 1 1 3 3 3 0 Importin-beta N-terminal domain RICTOR_V PF14668.6 OWF54743.1 - 0.038 14.2 0.1 0.39 11.0 0.0 2.4 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Myb_DNA-bind_5 PF13873.6 OWF54743.1 - 0.061 13.4 1.3 16 5.6 0.0 3.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NopRA1 PF16201.5 OWF54743.1 - 0.087 12.4 0.4 4.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 FA_FANCE PF11510.8 OWF54744.1 - 5.8e-26 91.4 5.0 8.4e-26 90.9 5.0 1.2 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE Sulfate_transp PF00916.20 OWF54745.1 - 8.3e-96 321.0 23.7 1.2e-95 320.6 23.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OWF54745.1 - 4.5e-26 90.8 0.0 1.3e-25 89.3 0.0 1.8 1 1 0 1 1 1 1 STAS domain Holin_BlyA PF05102.12 OWF54745.1 - 0.2 11.6 3.6 1.1 9.2 3.6 2.3 1 0 0 1 1 1 0 holin, BlyA family Patched PF02460.18 OWF54746.1 - 2.5e-142 475.7 20.6 3.1e-142 475.4 20.6 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OWF54746.1 - 2.3e-36 124.9 3.3 2.3e-36 124.9 3.3 3.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OWF54746.1 - 0.32 9.9 14.2 1.1 8.2 3.3 2.4 2 0 0 2 2 2 0 MMPL family ACR_tran PF00873.19 OWF54746.1 - 3.9 5.0 15.9 6 4.4 15.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family KR PF08659.10 OWF54747.1 - 2.8e-50 170.7 0.0 5.8e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 OWF54747.1 - 1.3e-46 159.5 0.0 2.2e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 OWF54747.1 - 2e-31 109.4 0.0 3.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 OWF54747.1 - 4.5e-22 78.3 0.1 1e-21 77.1 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 OWF54747.1 - 1.6e-14 54.3 0.1 6.5e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 OWF54747.1 - 8.5e-09 35.6 0.3 2.6e-08 34.1 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 OWF54747.1 - 4.7e-06 26.2 0.0 1.5e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF54747.1 - 1.4e-05 24.7 0.0 4.5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PALP PF00291.25 OWF54747.1 - 0.022 14.2 0.1 2.2 7.6 0.2 2.4 1 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ketoacyl-synt PF00109.26 OWF54748.1 - 9e-83 277.7 0.0 1.5e-82 277.0 0.0 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 OWF54748.1 - 3.4e-08 33.2 0.1 7.2e-08 32.1 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.22 OWF54748.1 - 1.2e-07 31.7 0.1 3.7e-07 30.2 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Aldo_ket_red PF00248.21 OWF54749.1 - 7.5e-48 163.2 0.0 1e-47 162.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Gal-3-0_sulfotr PF06990.11 OWF54750.1 - 4.1e-48 164.2 2.0 5.4e-48 163.8 2.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 OWF54750.1 - 6.6e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Thionin PF00321.17 OWF54751.1 - 0.00053 20.4 22.8 0.68 10.5 0.8 5.2 1 1 4 5 5 5 4 Plant thionin zf-nanos PF05741.13 OWF54751.1 - 0.017 15.3 15.7 16 5.8 0.9 5.0 1 1 2 3 3 3 0 Nanos RNA binding domain Frag1 PF10277.9 OWF54752.1 - 1.6e-41 142.2 15.8 2.1e-41 141.9 15.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1461 PF07314.11 OWF54752.1 - 2.1 8.2 10.5 1.2 9.0 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Glyco_transf_49 PF13896.6 OWF54754.1 - 3.5e-60 204.1 4.6 1.9e-46 159.0 0.5 3.1 2 2 1 3 3 3 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 OWF54754.1 - 2e-19 70.2 3.8 2e-19 70.2 3.8 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 OWF54754.1 - 8.6e-05 22.1 6.5 0.00015 21.2 6.5 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Dynamitin PF04912.14 OWF54754.1 - 0.0051 16.2 1.8 0.0085 15.5 1.8 1.2 1 0 0 1 1 1 1 Dynamitin Nucleotid_trans PF03407.16 OWF54754.1 - 0.016 15.2 3.2 0.063 13.2 0.3 2.8 3 0 0 3 3 3 0 Nucleotide-diphospho-sugar transferase AATF-Che1 PF13339.6 OWF54754.1 - 0.021 15.5 0.9 0.049 14.3 0.9 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor APG6_N PF17675.1 OWF54754.1 - 0.11 13.1 1.5 0.2 12.2 0.2 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region UQ_con PF00179.26 OWF54755.1 - 2.3e-38 131.0 0.0 2.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BSD PF03909.17 OWF54756.1 - 1.2e-23 82.8 1.3 6.4e-18 64.5 0.0 2.9 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 OWF54756.1 - 1.6e-20 73.2 0.0 3.6e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain SHOCT PF09851.9 OWF54756.1 - 0.039 13.7 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Short C-terminal domain SHIPPO-rpt PF07004.12 OWF54757.1 - 7.1e-05 23.5 0.8 0.21 12.5 0.2 3.4 2 1 0 2 2 2 2 Sperm-tail PG-rich repeat ECR1_N PF14382.6 OWF54757.1 - 0.16 11.8 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region PHD PF00628.29 OWF54758.1 - 4e-10 39.4 11.8 4e-10 39.4 11.8 3.2 4 0 0 4 4 4 1 PHD-finger zf-RING_2 PF13639.6 OWF54758.1 - 1.6e-08 34.7 25.5 4.7e-08 33.2 5.4 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 OWF54758.1 - 2.8e-06 27.1 5.1 2.8e-06 27.1 5.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF54758.1 - 3.4e-06 26.8 4.5 3.4e-06 26.8 4.5 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF54758.1 - 1e-05 25.4 5.8 3.6e-05 23.7 5.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF54758.1 - 5.4e-05 23.0 2.1 5.4e-05 23.0 2.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OWF54758.1 - 5.8e-05 23.3 2.7 5.8e-05 23.3 2.7 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OWF54758.1 - 0.00036 20.4 4.1 0.00036 20.4 4.1 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OWF54758.1 - 0.015 15.3 0.6 0.015 15.3 0.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OWF54758.1 - 0.87 9.8 17.1 0.011 15.8 5.0 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OWF54758.1 - 9.9 6.1 17.9 0.32 10.9 8.0 2.9 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 Peptidase_M20 PF01546.28 OWF54759.1 - 1.4e-35 122.9 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OWF54759.1 - 1.4e-15 57.2 0.0 3.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 OWF54759.1 - 0.0041 16.2 0.0 0.011 14.8 0.0 1.6 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 OWF54759.1 - 0.014 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Glyco_transf_54 PF04666.13 OWF54760.1 - 1.3e-72 244.2 3.6 1.3e-72 244.2 3.6 1.9 2 0 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region NUMOD1 PF07453.13 OWF54760.1 - 0.007 16.6 1.1 8.6 6.7 0.1 3.8 3 0 0 3 3 3 2 NUMOD1 domain Arm_vescicular PF18770.1 OWF54760.1 - 0.14 12.1 0.3 44 4.1 0.0 3.3 3 0 0 3 3 3 0 Armadillo tether-repeat of vescicular transport factor Pro_sub2 PF18513.1 OWF54760.1 - 0.61 10.3 7.9 12 6.2 0.0 4.8 5 0 0 5 5 5 0 Prodomain subtilisin 2 RRM_1 PF00076.22 OWF54761.1 - 3.5e-09 36.3 0.0 7.1e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RA PF00788.23 OWF54762.1 - 0.0032 18.1 0.0 0.0076 16.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF489 PF04356.12 OWF54762.1 - 0.4 10.7 9.3 0.52 10.3 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF489) Terminase_4 PF05119.12 OWF54762.1 - 0.84 10.1 5.4 0.55 10.7 0.2 3.1 3 2 0 3 3 3 0 Phage terminase, small subunit DUF4515 PF14988.6 OWF54762.1 - 2 8.2 16.1 0.031 14.1 4.5 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) YlqD PF11068.8 OWF54762.1 - 2 8.8 11.6 0.062 13.7 2.9 2.6 2 1 1 3 3 3 0 YlqD protein SlyX PF04102.12 OWF54762.1 - 5.8 7.6 10.0 27 5.5 0.8 3.8 3 0 0 3 3 3 0 SlyX SGL PF08450.12 OWF54764.1 - 5.3e-73 245.6 0.4 6.2e-73 245.4 0.4 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OWF54764.1 - 0.00076 19.6 0.0 0.013 15.7 0.0 2.6 3 0 0 3 3 3 1 Arylesterase Reg_prop PF07494.11 OWF54764.1 - 0.0013 18.7 0.3 3.2 8.3 0.0 2.8 2 0 0 2 2 2 2 Two component regulator propeller PQQ_2 PF13360.6 OWF54764.1 - 0.0051 16.4 0.1 4.8 6.7 0.0 3.1 1 1 2 3 3 3 2 PQQ-like domain Lactonase PF10282.9 OWF54764.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Peptidase_C4 PF00863.19 OWF54765.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C4 Nucleoporin_FG PF13634.6 OWF54766.1 - 2.8e-08 34.5 9.2 0.0044 17.8 1.1 3.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF3876 PF12992.7 OWF54766.1 - 9.9e-06 25.6 2.0 3.3 7.8 0.0 4.0 1 1 2 4 4 4 3 Domain of unknown function, B. Theta Gene description (DUF3876) Atracotoxin PF05353.11 OWF54766.1 - 0.0047 16.9 0.0 61 3.8 0.0 5.4 5 1 2 8 8 8 0 Delta Atracotoxin S-antigen PF05756.11 OWF54766.1 - 9.7 6.6 15.9 78 3.7 0.2 5.3 1 1 6 7 7 7 0 S-antigen protein Homeodomain PF00046.29 OWF54767.1 - 2.8e-13 49.5 0.9 5.6e-13 48.5 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Trypsin_2 PF13365.6 OWF54770.1 - 1.5e-10 42.2 0.0 2.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OWF54770.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.5 1 1 0 1 1 1 0 Trypsin DED PF01335.21 OWF54770.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Death effector domain Arc_PepC_II PF06847.11 OWF54770.1 - 0.23 12.0 1.5 50 4.5 0.1 3.4 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II HEPN_DZIP3 PF18738.1 OWF54772.1 - 1.4e-05 24.9 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN TIR_2 PF13676.6 OWF54772.1 - 0.064 13.9 0.0 0.16 12.6 0.0 1.6 1 1 0 1 1 1 0 TIR domain Sulfotransfer_2 PF03567.14 OWF54773.1 - 6.1e-29 101.7 0.8 1.7e-25 90.4 0.0 2.1 1 1 0 2 2 2 2 Sulfotransferase family Ribosomal_L27e PF01777.18 OWF54773.1 - 0.0057 17.0 0.1 2.2 8.7 0.1 2.9 3 0 0 3 3 3 2 Ribosomal L27e protein family DNA_PPF PF02916.15 OWF54774.1 - 0.02 15.3 0.1 0.041 14.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor Kinesin PF00225.23 OWF54775.1 - 3.9e-46 157.5 1.7 5.2e-46 157.1 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain DUF4472 PF14739.6 OWF54775.1 - 9e-28 97.1 14.0 9e-28 97.1 14.0 6.0 6 0 0 6 6 6 1 Domain of unknown function (DUF4472) Microtub_bd PF16796.5 OWF54775.1 - 1.3e-11 44.6 0.1 8.2e-10 38.8 0.0 2.8 2 0 0 2 2 2 1 Microtubule binding DUF724 PF05266.14 OWF54775.1 - 0.00051 19.9 3.9 0.00051 19.9 3.9 5.8 5 1 1 6 6 6 3 Protein of unknown function (DUF724) Scaffolding_pro PF11418.8 OWF54775.1 - 0.0096 16.5 0.1 0.0096 16.5 0.1 3.4 3 0 0 3 3 3 1 Phi29 scaffolding protein baeRF_family2 PF18844.1 OWF54775.1 - 0.03 14.4 1.4 0.18 11.9 0.1 2.9 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 KIP1 PF07765.12 OWF54775.1 - 5.9 7.1 8.0 5.8 7.1 3.9 3.2 2 0 0 2 2 2 0 KIP1-like protein 4HBT PF03061.22 OWF54776.1 - 5.3e-14 52.3 0.4 1.5e-13 50.9 0.2 1.7 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 OWF54776.1 - 8.1e-05 22.8 0.1 0.00011 22.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 OWF54776.1 - 9.8e-05 22.7 0.0 0.00014 22.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily ERCC4 PF02732.15 OWF54777.1 - 4.4e-25 88.7 0.0 9e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Ins134_P3_kin_N PF17927.1 OWF54777.1 - 0.088 13.2 0.0 12 6.3 0.0 3.2 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain HTH_53 PF18606.1 OWF54777.1 - 0.16 11.7 0.1 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain Macro PF01661.21 OWF54778.1 - 2.5e-17 63.0 0.0 8.8e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 Macro domain FKBP_C PF00254.28 OWF54779.1 - 2.3e-34 117.6 0.0 3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HECT PF00632.25 OWF54780.1 - 2.1e-95 319.8 0.4 8.7e-95 317.7 0.2 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 OWF54780.1 - 0.0004 19.9 0.3 0.0016 18.1 0.3 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Inp1 PF12634.7 OWF54780.1 - 0.053 13.5 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 TP_methylase PF00590.20 OWF54781.1 - 2.6e-23 83.1 0.0 7.7e-23 81.5 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DOT1 PF08123.13 OWF54782.1 - 5e-62 209.1 0.2 9.8e-62 208.1 0.2 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF3613 PF12266.8 OWF54782.1 - 0.11 12.3 1.1 0.49 10.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Spectrin PF00435.21 OWF54782.1 - 0.72 10.4 4.8 0.65 10.5 0.5 2.6 1 1 1 2 2 2 0 Spectrin repeat CLZ PF16526.5 OWF54782.1 - 1.4 9.3 9.3 1.4 9.3 1.2 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SNF2_N PF00176.23 OWF54783.1 - 3e-56 190.6 0.0 6.3e-56 189.6 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF54783.1 - 2.9e-16 59.8 0.0 8.8e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF54783.1 - 2.6e-09 37.3 0.0 4.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rad54_N PF08658.10 OWF54783.1 - 5.6e-07 29.9 0.0 2.8e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Rad54 N terminal HDA2-3 PF11496.8 OWF54783.1 - 2.7e-06 26.8 0.0 1.1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 OWF54783.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 OWF54783.1 - 0.12 12.7 0.1 1.7 8.9 0.0 2.8 2 2 0 2 2 2 0 AAA domain Rab5ip PF07019.12 OWF54784.1 - 1.9e-20 73.2 12.2 2.4e-20 72.9 12.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Sec7 PF01369.20 OWF54785.1 - 6.4e-35 120.5 0.2 9.3e-35 120.0 0.2 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 OWF54785.1 - 1.1e-05 25.2 0.7 2.4e-05 24.1 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF54785.1 - 2.2e-05 24.2 0.4 4.3e-05 23.3 0.4 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 OWF54785.1 - 0.069 13.5 0.1 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 PRANC domain MAGE_N PF12440.8 OWF54787.1 - 0.77 10.5 9.6 33 5.3 0.3 4.6 1 1 3 4 4 4 0 Melanoma associated antigen family N terminal CEP44 PF15007.6 OWF54788.1 - 6.5e-43 145.9 0.4 1.2e-42 145.1 0.4 1.4 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Alkyl_sulf_C PF14864.6 OWF54788.1 - 0.077 13.3 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal MgtE_N PF03448.17 OWF54789.1 - 0.071 13.7 0.0 11 6.7 0.0 2.6 1 1 2 3 3 3 0 MgtE intracellular N domain Tyrosinase PF00264.20 OWF54790.1 - 8.7e-35 121.0 1.6 1.2e-31 110.8 1.6 2.3 1 1 0 1 1 1 1 Common central domain of tyrosinase Fibrinogen_BP PF08017.11 OWF54791.1 - 8.4e-12 44.2 9.8 1.4e-11 43.5 9.8 1.3 1 0 0 1 1 1 1 Fibrinogen binding protein AdoHcyase_NAD PF00670.21 OWF54791.1 - 0.0004 20.5 49.1 3.6 7.7 2.3 7.6 1 1 8 9 9 9 9 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Flavi_NS1 PF00948.21 OWF54791.1 - 0.1 11.4 12.6 7.4 5.3 0.4 3.9 1 1 3 4 4 4 0 Flavivirus non-structural Protein NS1 DNA_pol_A PF00476.20 OWF54792.1 - 2.8e-111 372.2 0.0 2.8e-111 372.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family A UCH PF00443.29 OWF54792.1 - 7e-33 114.2 35.6 2.7e-32 112.3 35.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 OWF54792.1 - 4e-15 56.0 2.3 9.1e-15 54.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF54792.1 - 6.1e-11 42.7 0.1 5.6e-09 36.3 0.1 3.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4549 PF15082.6 OWF54793.1 - 4.6e-05 23.2 5.3 11 5.8 0.1 5.7 2 2 4 7 7 7 3 Domain of unknown function (DUF4549) DUF2654 PF10849.8 OWF54793.1 - 0.27 11.5 8.8 96 3.3 0.1 6.3 2 2 7 10 10 10 0 Protein of unknown function (DUF2654) UCH PF00443.29 OWF54794.1 - 2.9e-12 46.6 6.8 2.9e-12 46.6 6.8 2.7 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF54794.1 - 0.0015 18.2 7.3 0.0015 18.2 7.3 2.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OWF54795.1 - 1.9e-19 70.2 1.1 2e-19 70.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ish1 PF10281.9 OWF54795.1 - 0.0062 16.8 0.0 6.4 7.2 0.0 3.8 3 0 0 3 3 3 1 Putative stress-responsive nuclear envelope protein PI3K_P85_iSH2 PF16454.5 OWF54796.1 - 1e-50 171.4 125.7 0.9 9.1 1.0 31.2 1 1 31 32 32 32 31 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MCPsignal PF00015.21 OWF54796.1 - 1.3e-50 171.6 137.1 0.063 13.1 1.6 25.1 1 1 20 21 21 21 20 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 OWF54796.1 - 4.4e-47 159.7 84.1 0.11 12.4 0.5 19.7 1 1 23 25 25 25 25 Sec34-like family IFT57 PF10498.9 OWF54796.1 - 5.2e-46 157.3 86.3 0.0077 15.2 0.8 14.5 1 1 5 6 6 6 6 Intra-flagellar transport protein 57 EzrA PF06160.12 OWF54796.1 - 5.4e-42 143.7 108.2 0.0002 19.7 4.2 11.0 1 1 8 10 10 10 10 Septation ring formation regulator, EzrA WXG100 PF06013.12 OWF54796.1 - 4.1e-36 123.1 0.0 5.4 7.3 0.0 21.7 1 1 24 25 25 25 20 Proteins of 100 residues with WXG Laminin_II PF06009.12 OWF54796.1 - 8.6e-31 106.8 31.0 0.88 9.6 0.4 16.5 1 1 14 15 15 15 15 Laminin Domain II DUF948 PF06103.11 OWF54796.1 - 5.2e-29 100.3 24.0 5.2 7.4 0.1 16.6 1 1 20 21 21 21 17 Bacterial protein of unknown function (DUF948) PI_PP_I PF18363.1 OWF54796.1 - 6.2e-21 74.4 55.4 8.4 6.7 0.4 18.6 1 1 7 8 8 8 3 Phosphoinositide phosphatase insertion domain NleF_casp_inhib PF16809.5 OWF54796.1 - 2.2e-18 66.6 182.6 2.8 7.9 2.3 21.1 1 1 20 21 21 19 13 NleF caspase inhibitor FPP PF05911.11 OWF54796.1 - 1.1e-14 53.7 52.3 0.00053 18.3 9.8 4.3 1 1 2 3 3 3 3 Filament-like plant protein, long coiled-coil AIP3 PF03915.13 OWF54796.1 - 2.6e-09 36.7 44.7 1.8e+04 -28.8 44.7 7.8 1 1 0 1 1 0 0 Actin interacting protein 3 SHE3 PF17078.5 OWF54796.1 - 0.49 10.1 177.2 2.1e+02 1.5 18.7 12.8 1 1 3 4 4 1 0 SWI5-dependent HO expression protein 3 Mucin-like PF16058.5 OWF54797.1 - 1.5e-19 69.9 0.1 1.1e-06 28.6 0.1 4.4 2 1 2 4 4 4 4 Mucin-like Apolipoprotein PF01442.18 OWF54797.1 - 0.00029 20.8 0.1 0.18 11.6 0.4 3.7 1 1 1 3 3 3 1 Apolipoprotein A1/A4/E domain Mt_ATP-synt_D PF05873.12 OWF54797.1 - 1.6 8.6 15.8 24 4.7 0.2 6.3 3 2 4 7 7 7 0 ATP synthase D chain, mitochondrial (ATP5H) UCH PF00443.29 OWF54798.1 - 3e-25 89.2 0.1 8.9e-25 87.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF54798.1 - 3.9e-08 33.3 4.5 1.2e-07 31.7 4.5 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3511 PF12023.8 OWF54798.1 - 0.35 10.7 1.9 0.9 9.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) GASA PF02704.14 OWF54799.1 - 0.0024 18.0 23.3 2.6 8.2 1.5 5.8 1 1 3 5 5 5 4 Gibberellin regulated protein Mustang PF15682.5 OWF54799.1 - 0.0036 17.4 7.2 2.3 8.4 0.6 3.7 1 1 3 4 4 4 2 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Imm1 PF14430.6 OWF54799.1 - 0.021 15.5 3.1 0.86 10.3 0.4 2.8 1 1 1 2 2 2 0 Immunity protein Imm1 SPC25 PF06703.11 OWF54799.1 - 0.19 11.5 4.3 33 4.2 4.3 2.9 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ldh_2 PF02615.14 OWF54799.1 - 8.6 5.4 14.1 3.6 6.7 0.9 2.9 1 1 2 3 3 3 0 Malate/L-lactate dehydrogenase CD34_antigen PF06365.12 OWF54800.1 - 0.037 13.6 0.0 0.094 12.3 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF4519 PF15012.6 OWF54800.1 - 0.13 12.4 0.4 0.24 11.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) EphA2_TM PF14575.6 OWF54801.1 - 0.032 15.1 0.4 0.098 13.5 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 OWF54801.1 - 0.21 11.5 7.2 0.27 11.2 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Insulin_TMD PF17870.1 OWF54802.1 - 0.0036 17.3 0.2 0.0083 16.2 0.2 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF3377 PF11857.8 OWF54802.1 - 0.067 13.1 0.2 0.067 13.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TFIIA PF03153.13 OWF54802.1 - 0.28 11.1 5.5 0.36 10.8 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4980 PF16352.5 OWF54803.1 - 7.4e-09 35.5 31.6 1.1 9.2 0.2 8.8 2 2 7 9 9 9 6 Domain of unknown function (DUF4980) Haem_degrading PF03928.14 OWF54803.1 - 9.3e-06 25.7 20.0 15 5.7 0.1 9.0 2 2 6 9 9 9 1 Haem-degrading Csm1_B PF18211.1 OWF54803.1 - 0.0021 17.9 4.9 51 3.8 0.1 5.4 1 1 2 5 5 5 0 Csm1 subunit domain B SHR-BD PF06650.12 OWF54803.1 - 0.0079 15.6 8.5 0.0098 15.3 1.0 3.1 1 1 2 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 DUF1205 PF06722.12 OWF54803.1 - 0.012 15.7 29.6 2.5 8.3 0.3 7.4 1 1 8 9 9 9 0 Protein of unknown function (DUF1205) FlgD_ig PF13860.6 OWF54803.1 - 0.051 13.4 20.1 25 4.8 0.2 8.2 2 2 7 9 9 9 0 FlgD Ig-like domain DUF5462 PF17547.2 OWF54803.1 - 0.12 11.7 34.0 4.5 6.6 0.7 6.6 1 1 4 6 6 6 0 Family of unknown function (DUF5462) Cas_Cas2CT1978 PF09707.10 OWF54803.1 - 0.42 10.7 12.8 27 4.9 0.1 5.7 2 1 4 7 7 7 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF1743 PF08489.11 OWF54803.1 - 1.4 9.0 7.7 3.1 7.9 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1743) DUF1043 PF06295.12 OWF54803.1 - 1.5 8.9 13.5 8.8 6.3 0.3 4.9 2 1 3 5 5 5 0 Protein of unknown function (DUF1043) YfhO PF09586.10 OWF54803.1 - 2.6 6.2 8.6 6.1 4.9 2.9 2.1 1 1 1 2 2 2 0 Bacterial membrane protein YfhO HATPase_c_5 PF14501.6 OWF54803.1 - 4.3 7.3 14.6 25 4.8 2.7 5.5 2 2 2 4 4 4 0 GHKL domain FGFR3_TM PF18123.1 OWF54804.1 - 0.8 9.3 12.1 22 4.7 0.6 5.6 6 1 1 7 7 7 0 Fibroblast growth factor receptor 3 transmembrane domain Phage_holin_2_3 PF16080.5 OWF54805.1 - 0.22 11.3 0.4 0.43 10.4 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Pkinase_Tyr PF07714.17 OWF54806.1 - 1.5e-85 286.6 0.0 2.2e-85 286.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF54806.1 - 1.3e-39 136.2 0.0 1.9e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ldl_recept_a PF00057.18 OWF54806.1 - 0.0012 19.0 1.6 0.0012 19.0 1.6 2.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A Kinase-like PF14531.6 OWF54806.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Orthoreo_P17 PF07272.11 OWF54807.1 - 0.35 10.9 27.6 33 4.5 0.3 8.6 3 2 8 11 11 11 0 Orthoreovirus P17 protein Fer4_11 PF13247.6 OWF54808.1 - 0.086 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain CRF PF00473.17 OWF54809.1 - 0.13 12.3 0.2 26 5.0 0.0 2.6 2 0 0 2 2 2 0 Corticotropin-releasing factor family EphA2_TM PF14575.6 OWF54809.1 - 0.17 12.8 0.8 0.39 11.6 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRRC37AB_C PF14914.6 OWF54810.1 - 0.15 12.0 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SOBP PF15279.6 OWF54810.1 - 2.9 8.4 29.5 4.6 7.8 29.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein TMEM154 PF15102.6 OWF54811.1 - 0.012 15.5 1.7 0.012 15.5 1.7 2.7 1 1 1 2 2 2 0 TMEM154 protein family Syndecan PF01034.20 OWF54811.1 - 0.038 13.9 0.3 0.079 12.9 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Glycophorin_A PF01102.18 OWF54811.1 - 0.094 13.0 0.2 0.094 13.0 0.2 2.8 3 1 0 3 3 3 0 Glycophorin A EphA2_TM PF14575.6 OWF54811.1 - 0.51 11.3 2.5 1.8 9.5 2.5 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TFIID_20kDa PF03847.13 OWF54813.1 - 7.1e-33 112.9 4.1 9.6e-33 112.5 4.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OWF54813.1 - 2.2e-05 24.7 0.1 4.1e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OWF54813.1 - 0.00018 21.5 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 OWF54813.1 - 0.0002 21.7 0.1 0.00034 21.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Tic110 PF16940.5 OWF54813.1 - 0.018 13.6 0.1 0.023 13.2 0.1 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter TAF PF02969.17 OWF54813.1 - 0.073 13.3 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TAF4 PF05236.14 OWF54813.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4078 PF13300.6 OWF54814.1 - 1.5e-24 86.1 8.0 1.5e-24 86.1 8.0 4.5 5 1 0 5 5 5 1 Domain of unknown function (DUF4078) Peptidase_S76 PF13611.6 OWF54814.1 - 0.074 13.4 0.8 0.35 11.2 0.8 2.2 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Tctex-1 PF03645.13 OWF54815.1 - 8.3e-35 119.1 0.7 9.4e-35 119.0 0.7 1.0 1 0 0 1 1 1 1 Tctex-1 family PTP2 PF17022.5 OWF54815.1 - 0.015 15.0 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia Caveolin PF01146.17 OWF54816.1 - 5.7e-25 87.8 0.1 7.9e-25 87.3 0.1 1.1 1 0 0 1 1 1 1 Caveolin BTB_3 PF16017.5 OWF54817.1 - 4.9e-50 168.0 0.0 9.1e-50 167.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 OWF54817.1 - 9e-05 22.8 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain 7tm_1 PF00001.21 OWF54818.1 - 9.1e-27 94.0 20.9 9.1e-27 94.0 20.9 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF54818.1 - 2.7e-05 24.0 6.8 2.7e-05 24.0 6.8 2.5 2 1 1 3 3 3 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF54818.1 - 0.0011 18.4 17.5 0.0021 17.5 17.5 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Aminopep PF10023.9 OWF54818.1 - 0.12 11.7 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative aminopeptidase DUF4695 PF15766.5 OWF54819.1 - 4.1e-10 39.8 1.2 7.3e-10 39.0 0.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4695) Sulfotransfer_2 PF03567.14 OWF54820.1 - 5e-30 105.2 0.3 1.8e-26 93.6 0.1 2.4 2 0 0 2 2 2 2 Sulfotransferase family GpcrRhopsn4 PF10192.9 OWF54822.1 - 1e-57 195.5 11.0 1.3e-57 195.1 11.0 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF1146 PF06612.11 OWF54822.1 - 0.04 14.0 1.5 4.4 7.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) LIM PF00412.22 OWF54822.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 LIM domain zf-C2H2_4 PF13894.6 OWF54823.1 - 7.5e-18 63.7 88.0 0.00034 21.2 0.6 10.7 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF54823.1 - 2.4e-11 43.4 92.4 6.8e-05 23.1 0.8 10.9 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF54823.1 - 6.3e-11 42.2 64.6 0.00025 21.3 0.8 10.9 11 0 0 11 11 11 6 Zinc-finger double domain zf-Di19 PF05605.12 OWF54823.1 - 2.6e-06 27.6 61.6 0.026 14.8 1.8 8.5 6 1 3 9 9 9 7 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OWF54823.1 - 2.1e-05 24.7 48.0 0.01 16.2 0.3 7.7 8 0 0 8 8 8 4 Zinc-finger of C2H2 type RFX5_DNA_bdg PF14621.6 OWF54823.1 - 2.6e-05 24.1 5.3 0.0041 16.9 1.1 2.3 2 0 0 2 2 2 2 RFX5 DNA-binding domain zf-C2H2_jaz PF12171.8 OWF54823.1 - 9.6e-05 22.6 6.1 0.00089 19.5 0.7 10.2 10 0 0 10 10 10 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 OWF54823.1 - 0.36 10.8 0.0 0.36 10.8 0.0 7.6 8 0 0 8 8 8 0 zinc-finger of a C2HC-type AT_hook PF02178.19 OWF54823.1 - 6.5 7.0 19.6 0.11 12.4 3.9 2.9 2 0 0 2 2 2 0 AT hook motif W_rich_C PF07483.11 OWF54824.1 - 0.018 15.2 8.1 20 5.4 0.1 5.0 1 1 6 7 7 7 0 Tryptophan-rich Synechocystis species C-terminal domain DUF4865 PF16157.5 OWF54824.1 - 0.37 10.8 16.2 33 4.4 0.4 5.5 1 1 7 8 8 8 0 Domain of unknown function (DUF4865) MatP_C PF17414.2 OWF54824.1 - 8.4 6.7 27.2 33 4.8 0.5 6.1 1 1 4 6 6 6 0 MatP C-terminal ribbon-helix-helix domain LCM PF04072.14 OWF54825.1 - 2.4e-31 109.2 0.0 7.3e-31 107.6 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase CDC27 PF09507.10 OWF54826.1 - 2.8e-68 231.3 63.9 7.5e-68 229.9 63.9 1.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 RhoGEF PF00621.20 OWF54827.1 - 6.1e-32 111.3 0.2 6.1e-32 111.3 0.2 1.7 2 0 0 2 2 2 1 RhoGEF domain betaPIX_CC PF16523.5 OWF54827.1 - 4.6e-25 87.3 8.4 1.4e-24 85.7 8.4 1.8 1 0 0 1 1 1 1 betaPIX coiled coil SH3_9 PF14604.6 OWF54827.1 - 2.6e-15 56.0 0.0 5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OWF54827.1 - 5.1e-14 51.7 0.2 1.9e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OWF54827.1 - 1.8e-13 49.9 0.1 3.9e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain RhoGEF67_u2 PF16614.5 OWF54827.1 - 8.1e-13 48.4 2.8 8.1e-13 48.4 2.8 2.7 2 1 0 2 2 2 1 Unstructured region two on RhoGEF 6 and 7 PH PF00169.29 OWF54827.1 - 2.3e-06 28.1 0.0 1.6e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 PH domain APG6_N PF17675.1 OWF54827.1 - 0.093 13.3 5.2 0.56 10.7 1.8 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region Tup_N PF08581.10 OWF54827.1 - 0.18 12.1 4.6 0.14 12.5 1.5 2.4 2 0 0 2 2 2 0 Tup N-terminal CENP-Q PF13094.6 OWF54827.1 - 0.21 11.8 5.4 0.7 10.1 5.4 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YscO PF07321.12 OWF54827.1 - 0.39 10.7 9.1 0.15 12.0 5.1 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO DUF724 PF05266.14 OWF54827.1 - 0.43 10.4 5.4 0.95 9.3 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Rho_N PF07498.12 OWF54829.1 - 0.024 14.5 0.6 0.041 13.8 0.6 1.3 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain THAP PF05485.12 OWF54830.1 - 1.8e-13 51.2 2.3 2.7e-13 50.7 2.1 1.5 1 1 0 1 1 1 1 THAP domain Terpene_synth_C PF03936.16 OWF54831.1 - 0.035 13.4 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain TNF PF00229.18 OWF54833.1 - 7.6e-12 45.3 0.0 1.7e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 OWF54834.1 - 0.0011 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family GRIP PF01465.20 OWF54835.1 - 0.0022 17.8 0.0 96 3.0 0.0 6.2 6 1 0 6 6 6 0 GRIP domain Plasmodium_HRP PF05403.11 OWF54835.1 - 0.0047 16.8 153.5 0.024 14.4 43.0 4.8 1 1 4 5 5 5 2 Plasmodium histidine-rich protein (HRPII/III) Ecotin PF03974.13 OWF54835.1 - 0.097 12.7 0.2 37 4.3 0.0 3.6 3 1 0 4 4 4 0 Ecotin ASD2 PF08687.11 OWF54835.1 - 5.7 6.4 13.0 8.8 5.8 0.8 3.7 2 1 2 4 4 4 0 Apx/Shroom domain ASD2 TNF PF00229.18 OWF54836.1 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 OWF54837.1 - 1.3e-08 34.8 0.1 2.3e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 OWF54838.1 - 0.00083 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 OWF54839.1 - 4.6e-10 39.5 1.3 8.2e-10 38.7 1.3 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 OWF54840.1 - 2.7e-06 27.3 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Myc_target_1 PF15179.6 OWF54840.1 - 0.01 15.7 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Myc target protein 1 TNF PF00229.18 OWF54841.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family 7TM_GPCR_Srt PF10321.9 OWF54842.1 - 0.099 11.6 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt TNF PF00229.18 OWF54843.1 - 0.00021 21.2 0.1 0.00069 19.6 0.1 1.9 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.18 OWF54844.1 - 4.9e-05 23.3 0.2 8.2e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family GlcV_C_terminal PF17847.1 OWF54847.1 - 0.73 10.3 15.6 54 4.4 0.4 6.3 2 1 4 6 6 6 0 Glucose ABC transporter C-terminal domain ULD PF16534.5 OWF54848.1 - 7.8 6.6 5.5 35 4.5 0.1 2.9 1 1 2 3 3 3 0 Ubiquitin-like oligomerisation domain of SATB DUF4573 PF15140.6 OWF54850.1 - 0.0018 18.1 5.1 0.003 17.4 3.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) XisI PF08869.11 OWF54850.1 - 0.017 15.4 3.1 24 5.3 0.1 3.5 1 1 3 4 4 4 0 XisI protein DNAPolymera_Pol PF11590.8 OWF54850.1 - 1.6 8.7 43.4 31 4.5 0.1 12.1 5 4 7 12 12 12 0 DNA polymerase catalytic subunit Pol Glutenin_hmw PF03157.13 OWF54850.1 - 5 5.4 30.2 14 4.0 30.0 1.5 1 1 1 2 2 2 0 High molecular weight glutenin subunit Colicin_D PF11429.8 OWF54851.1 - 0.00039 20.8 6.9 7.1 7.1 0.0 5.3 1 1 4 5 5 5 2 Colicin D DNA_repr_REX1B PF14966.6 OWF54851.1 - 0.016 15.9 3.3 4 8.2 0.1 3.5 2 2 2 4 4 4 0 DNA repair REX1-B DND1_DSRM PF14709.7 OWF54851.1 - 0.15 12.3 11.6 14 6.0 0.3 4.9 1 1 5 6 6 6 0 double strand RNA binding domain from DEAD END PROTEIN 1 Phage_int_SAM_3 PF14659.6 OWF54851.1 - 0.21 11.9 24.7 6.7 7.1 0.4 5.9 6 0 0 6 6 6 0 Phage integrase, N-terminal SAM-like domain TNF PF00229.18 OWF54852.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family TMIE PF16038.5 OWF54853.1 - 0.044 13.6 2.5 0.064 13.1 2.5 1.3 1 0 0 1 1 1 0 TMIE protein LodA_N PF17990.1 OWF54853.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal CHASE5 PF17149.4 OWF54854.1 - 0.0023 17.9 0.1 0.0052 16.7 0.1 1.7 1 0 0 1 1 1 1 Periplasmic sensor domain found in signal transduction proteins HTH_40 PF14493.6 OWF54854.1 - 0.019 15.4 0.3 8.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain CK2S PF15011.6 OWF54854.1 - 0.026 14.4 0.0 0.63 9.9 0.0 2.3 1 1 0 1 1 1 0 Casein Kinase 2 substrate ASH PF15780.5 OWF54855.1 - 5.3e-18 65.0 1.4 0.00041 20.5 0.0 8.2 7 2 0 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 OWF54855.1 - 1.2e-14 54.4 0.8 0.026 14.8 0.0 7.7 7 1 0 7 7 7 3 Transmembrane protein 131-like DUF1573 PF07610.11 OWF54855.1 - 0.00041 20.3 0.0 27 4.9 0.0 5.7 6 0 0 6 6 6 1 Protein of unknown function (DUF1573) PapD-like PF14874.6 OWF54855.1 - 0.038 14.2 0.1 2.5 8.3 0.0 3.8 5 0 0 5 5 5 0 Flagellar-associated PapD-like Septin PF00735.18 OWF54856.1 - 1.1e-122 408.8 0.0 1.1e-122 408.8 0.0 1.8 2 0 0 2 2 1 1 Septin MMR_HSR1 PF01926.23 OWF54856.1 - 1.7e-07 31.3 1.5 2.6e-07 30.7 0.0 2.1 2 1 1 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF54856.1 - 9.9e-06 25.6 4.8 2.7e-05 24.1 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 OWF54856.1 - 0.00018 20.9 0.0 0.00018 20.9 0.0 2.1 2 0 0 2 2 1 1 AIG1 family FeoB_N PF02421.18 OWF54856.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Fez1 PF06818.15 OWF54856.1 - 0.0053 17.2 13.1 0.0096 16.4 13.1 1.4 1 0 0 1 1 1 1 Fez1 Ras PF00071.22 OWF54856.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 OWF54856.1 - 0.012 15.9 0.2 0.04 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OWF54856.1 - 0.017 15.6 2.5 0.066 13.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 OWF54856.1 - 0.027 14.7 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OWF54856.1 - 0.031 14.5 1.2 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OWF54856.1 - 0.047 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 OWF54856.1 - 0.057 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Exonuc_VII_L PF02601.15 OWF54856.1 - 0.093 12.3 6.7 0.14 11.7 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FtsK_SpoIIIE PF01580.18 OWF54856.1 - 0.14 11.5 2.6 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family LMBR1 PF04791.16 OWF54856.1 - 0.34 9.8 0.3 0.36 9.7 0.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4633 PF15464.6 OWF54856.1 - 0.47 10.6 4.8 0.98 9.6 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Hid1 PF12722.7 OWF54856.1 - 0.82 7.7 8.1 1.1 7.3 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Prominin PF05478.11 OWF54856.1 - 2.3 6.1 5.9 3.1 5.6 5.9 1.1 1 0 0 1 1 1 0 Prominin DUF883 PF05957.13 OWF54856.1 - 2.3 8.9 7.6 5 7.8 7.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 OWF54856.1 - 4.3 7.7 18.0 10 6.4 18.0 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 OWF54856.1 - 4.6 7.3 8.6 29 4.7 4.7 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_lig_T4_1 PF09511.10 OWF54857.1 - 0.00017 21.5 6.0 3.8 7.3 0.0 5.1 1 1 5 6 6 6 4 RNA ligase FAF PF11250.8 OWF54857.1 - 0.096 12.9 8.0 3.5 7.9 0.1 4.3 4 1 0 5 5 5 0 Fantastic Four meristem regulator UPF0176_N PF17773.1 OWF54857.1 - 0.16 12.3 7.7 16 5.9 0.1 4.7 1 1 5 6 6 6 0 UPF0176 acylphosphatase like domain eIF3m_C_helix PF18005.1 OWF54857.1 - 1.8 8.3 31.8 1.7 8.4 0.4 6.2 6 0 0 6 6 6 0 eIF3 subunit M, C-terminal helix EAL PF00563.20 OWF54858.1 - 0.05 13.1 0.7 6.4 6.2 0.0 2.9 1 1 0 2 2 2 0 EAL domain Dpoe2NT PF12213.8 OWF54858.1 - 0.053 13.8 5.5 10 6.5 0.0 5.4 3 1 4 7 7 7 0 DNA polymerases epsilon N terminal DASH_Dam1 PF08653.10 OWF54858.1 - 0.27 11.1 34.2 17 5.3 1.0 8.6 2 2 7 9 9 9 0 DASH complex subunit Dam1 N_formyltrans_C PF18216.1 OWF54858.1 - 0.42 10.3 0.0 0.42 10.3 0.0 3.0 4 0 0 4 4 4 0 N-formyltransferase dimerization C-terminal domain Sfi1 PF08457.10 OWF54858.1 - 0.54 8.7 14.9 0.27 9.7 7.4 2.3 2 0 0 2 2 2 0 Sfi1 spindle body protein PLU-1 PF08429.11 OWF54858.1 - 3.2 6.8 13.7 9.3 5.3 1.1 2.9 1 1 1 2 2 2 0 PLU-1-like protein Dpoe2NT PF12213.8 OWF54860.1 - 0.22 11.8 6.0 99 3.3 0.1 4.8 2 1 4 6 6 6 0 DNA polymerases epsilon N terminal DASH_Dam1 PF08653.10 OWF54860.1 - 0.36 10.7 23.7 15 5.5 0.2 6.0 1 1 3 6 6 6 0 DASH complex subunit Dam1 Sfi1 PF08457.10 OWF54860.1 - 0.63 8.5 12.5 0.31 9.5 7.3 1.7 1 1 1 2 2 2 0 Sfi1 spindle body protein Snf7 PF03357.21 OWF54860.1 - 7.2 6.2 19.6 1.8 8.1 8.6 2.7 1 1 2 3 3 3 0 Snf7 Desmo_N PF06771.11 OWF54860.1 - 9.9 6.6 12.4 11 6.4 0.8 2.8 1 1 2 3 3 3 0 Viral Desmoplakin N-terminus DASH_Dam1 PF08653.10 OWF54861.1 - 0.00068 19.4 30.6 3 7.7 0.6 7.6 2 2 6 8 8 8 4 DASH complex subunit Dam1 Mx_ML PF17536.2 OWF54861.1 - 0.0024 17.6 0.4 2.2 8.0 0.1 3.1 1 1 2 3 3 3 3 Matrix and Matrix long proteins N-terminal HisG_C PF08029.11 OWF54861.1 - 0.035 14.3 8.7 8.5 6.6 0.0 6.1 2 2 4 7 7 7 0 HisG, C-terminal domain Dpoe2NT PF12213.8 OWF54861.1 - 0.053 13.8 6.2 17 5.8 0.1 5.0 2 2 3 5 5 5 0 DNA polymerases epsilon N terminal DNA_ligase_aden PF01653.18 OWF54861.1 - 2 7.4 7.6 2.5 7.1 1.6 2.3 1 1 1 2 2 2 0 NAD-dependent DNA ligase adenylation domain Desmo_N PF06771.11 OWF54861.1 - 2 8.8 22.1 9.1 6.7 2.7 4.1 1 1 4 5 5 5 0 Viral Desmoplakin N-terminus zf-B_box PF00643.24 OWF54863.1 - 1.1e-12 47.9 19.7 9.1e-10 38.5 3.7 3.9 4 0 0 4 4 4 2 B-box zinc finger NHL PF01436.21 OWF54863.1 - 7.2e-07 28.9 16.1 0.0097 15.9 0.5 6.8 7 1 1 8 8 8 3 NHL repeat zf-C3HC4 PF00097.25 OWF54863.1 - 4.1e-06 26.6 6.6 4.1e-06 26.6 6.6 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF54863.1 - 5.7e-06 26.1 5.0 5.7e-06 26.1 5.0 4.1 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF54863.1 - 4.5e-05 23.3 6.1 4.5e-05 23.3 6.1 4.4 3 1 1 4 4 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF54863.1 - 7.2e-05 23.0 7.1 7.2e-05 23.0 7.1 4.1 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 OWF54863.1 - 0.00045 20.0 5.5 0.00045 20.0 5.5 4.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OWF54863.1 - 0.0016 18.6 6.1 0.0016 18.6 6.1 4.0 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF54863.1 - 0.0041 17.1 7.4 0.0041 17.1 7.4 3.9 4 0 0 4 4 4 1 RING-type zinc-finger Reg_prop PF07494.11 OWF54863.1 - 0.015 15.4 0.0 1 9.8 0.0 3.7 3 0 0 3 3 2 0 Two component regulator propeller SGL PF08450.12 OWF54863.1 - 0.026 14.1 0.2 2.7 7.5 0.1 3.2 1 1 2 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Not3 PF04065.15 OWF54863.1 - 0.036 13.5 2.0 0.057 12.9 2.0 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF5449 PF17528.2 OWF54863.1 - 0.19 11.5 1.2 10 5.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5449) Vac_Fusion PF02346.16 OWF54863.1 - 0.73 9.5 3.7 18 5.0 0.3 3.4 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Synaptobrevin PF00957.21 OWF54864.1 - 1.3e-32 111.4 2.4 2.5e-32 110.5 2.4 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OWF54864.1 - 1.1e-25 89.4 0.4 1.8e-25 88.8 0.4 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain MSC PF09402.10 OWF54864.1 - 0.011 15.2 0.8 0.014 14.9 0.8 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain RIFIN PF02009.16 OWF54864.1 - 0.015 15.2 0.8 0.018 15.0 0.8 1.2 1 0 0 1 1 1 0 Rifin ANAPC16 PF17256.2 OWF54864.1 - 0.079 13.3 0.9 0.24 11.8 0.4 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, subunit 16 Sigma_reg_N PF13800.6 OWF54864.1 - 0.18 12.1 2.7 0.41 11.0 2.7 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Orf78 PF06024.12 OWF54864.1 - 0.26 11.6 4.0 0.49 10.7 4.0 1.6 1 1 0 1 1 1 0 Orf78 (ac78) DUF229 PF02995.17 OWF54865.1 - 3.4e-112 375.6 2.0 3.4e-112 375.6 2.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF54865.1 - 4.2e-06 26.4 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OWF54865.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase SH3_9 PF14604.6 OWF54866.1 - 2.8e-47 158.4 7.1 1.1e-14 54.1 0.1 4.6 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 OWF54866.1 - 7.3e-46 153.6 12.6 1.1e-15 56.9 0.3 4.8 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 OWF54866.1 - 3.2e-37 126.0 3.3 3.9e-13 48.9 0.1 4.6 5 0 0 5 5 5 4 Variant SH3 domain DUF5336 PF17270.2 OWF54866.1 - 0.0036 17.0 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5336) Neprosin PF03080.15 OWF54866.1 - 0.078 12.3 0.4 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Neprosin SH3_3 PF08239.11 OWF54866.1 - 0.13 12.6 3.6 0.078 13.3 0.3 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain DUF5534 PF17686.1 OWF54866.1 - 0.19 11.9 0.1 0.64 10.3 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5534) SH3_16 PF18348.1 OWF54866.1 - 1.5 8.7 5.5 29 4.6 0.0 3.4 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain GLTT PF01744.20 OWF54867.1 - 0.00016 21.3 16.3 23 4.9 0.3 9.7 6 4 1 7 7 7 1 GLTT repeat (6 copies) DUF1717 PF05414.11 OWF54867.1 - 0.00024 21.5 5.7 2.4 8.6 0.1 4.5 1 1 3 4 4 4 4 Viral domain of unknown function (DUF1717) DUF4385 PF14328.6 OWF54867.1 - 0.0057 16.7 10.4 6.4 6.8 0.3 4.2 1 1 4 5 5 5 4 Domain of unknown function (DUF4385) DUF3069 PF11269.8 OWF54867.1 - 0.048 13.9 0.7 52 4.1 0.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3069) Orthopox_F8 PF05886.11 OWF54867.1 - 0.33 11.1 4.1 49 4.1 0.1 5.2 1 1 2 3 3 3 0 Orthopoxvirus F8 protein AIRS_C PF02769.22 OWF54867.1 - 0.39 10.8 5.5 26 4.9 0.0 4.2 2 2 2 5 5 5 0 AIR synthase related protein, C-terminal domain VWD PF00094.25 OWF54868.1 - 8.1e-24 84.7 0.7 1.4e-23 83.9 0.7 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain TIL PF01826.17 OWF54868.1 - 4.1e-07 30.1 10.6 4.1e-07 30.1 10.6 17.4 4 1 13 17 17 17 3 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 OWF54868.1 - 0.0049 17.0 5.7 0.0049 17.0 5.7 18.4 15 3 3 18 18 18 9 EGF domain cEGF PF12662.7 OWF54868.1 - 0.019 14.9 0.6 0.019 14.9 0.6 15.2 15 0 0 15 15 15 0 Complement Clr-like EGF-like VWD PF00094.25 OWF54870.1 - 4.9e-30 104.9 1.2 8.6e-30 104.1 1.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 OWF54870.1 - 3.3e-11 43.5 1.9 3.3e-11 43.5 1.9 4.7 5 1 0 5 5 5 1 C8 domain TIL PF01826.17 OWF54870.1 - 3.7e-08 33.5 11.6 3.7e-08 33.5 11.6 6.7 6 1 2 8 8 8 2 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 OWF54870.1 - 0.00016 21.8 6.3 0.00016 21.8 6.3 7.8 6 2 0 6 6 6 4 EGF domain Baculo_PEP_C PF04513.12 OWF54871.1 - 3.3e-05 23.9 0.0 0.0072 16.4 0.0 2.3 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TAF6_C PF07571.13 OWF54871.1 - 0.0034 17.7 0.2 30 5.0 0.0 3.3 1 1 4 5 5 5 4 TAF6 C-terminal HEAT repeat domain AI-2E_transport PF01594.16 OWF54871.1 - 0.11 11.7 4.4 1.8 7.7 4.4 2.2 1 1 0 1 1 1 0 AI-2E family transporter MIEAP PF16026.5 OWF54872.1 - 2.2e-23 83.5 0.0 2.2e-23 83.5 0.0 2.8 3 0 0 3 3 3 1 Mitochondria-eating protein kleA_kleC PF17383.2 OWF54872.1 - 0.091 13.1 3.9 0.1 12.9 0.7 2.6 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 OWF54872.1 - 0.1 11.4 21.9 0.045 12.6 5.7 3.4 3 0 0 3 3 3 0 Spc7 kinetochore protein Hrs_helical PF12210.8 OWF54872.1 - 1.9 9.1 11.9 13 6.4 2.7 3.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate SlyX PF04102.12 OWF54872.1 - 2.1 9.0 17.8 5.1 7.8 0.1 4.5 4 0 0 4 4 4 0 SlyX Laminin_II PF06009.12 OWF54872.1 - 2.6 8.0 16.5 0.32 11.0 4.6 2.9 2 0 0 2 2 2 0 Laminin Domain II DUF5082 PF16888.5 OWF54872.1 - 2.8 8.2 18.5 3.5 7.9 2.5 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Tom7 PF08038.12 OWF54873.1 - 0.0019 17.8 1.6 0.85 9.3 0.1 4.0 2 1 3 5 5 5 1 TOM7 family DASH_Ask1 PF08655.10 OWF54873.1 - 0.022 14.6 1.8 14 5.7 0.1 3.8 1 1 3 4 4 4 0 DASH complex subunit Ask1 DER1 PF04511.15 OWF54873.1 - 0.17 11.8 4.1 1.5 8.7 0.3 2.1 1 1 1 2 2 2 0 Der1-like family DUF3982 PF13138.6 OWF54873.1 - 0.17 11.7 9.4 27 4.7 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3982) UPF0239 PF06783.11 OWF54873.1 - 0.33 11.2 2.1 52 4.1 0.0 3.8 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0239) GnRH PF00446.17 OWF54873.1 - 8.2 7.1 8.8 1.7e+02 3.0 0.1 4.2 4 0 0 4 4 4 0 Gonadotropin-releasing hormone PH_4 PF15404.6 OWF54874.1 - 0.0036 17.1 3.4 0.82 9.4 0.2 2.5 1 1 1 2 2 2 2 Pleckstrin homology domain DCP1 PF06058.13 OWF54874.1 - 0.052 13.5 0.6 3.5 7.6 0.1 2.2 1 1 1 2 2 2 0 Dcp1-like decapping family Papo_T_antigen PF02380.15 OWF54874.1 - 0.089 12.9 12.5 14 5.9 0.2 3.9 1 1 3 4 4 4 0 T-antigen specific domain Zn_ribbon_17 PF17120.5 OWF54874.1 - 0.097 12.3 14.4 1.1 8.9 1.3 3.8 1 1 3 4 4 4 0 Zinc-ribbon, C4HC2 type His_binding PF02098.16 OWF54874.1 - 0.11 12.6 3.9 0.27 11.3 3.9 1.6 1 1 0 1 1 1 0 Tick histamine binding protein PPTA PF01239.22 OWF54874.1 - 0.14 12.0 8.4 19 5.2 0.1 3.9 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat TRI9 PF08195.11 OWF54874.1 - 0.23 11.4 6.4 4.3 7.3 0.0 3.7 3 1 1 4 4 4 0 TRI9 protein PglZ PF08665.12 OWF54874.1 - 0.43 10.6 2.7 5.2 7.1 0.2 2.8 1 1 2 3 3 3 0 PglZ domain RINGv PF12906.7 OWF54874.1 - 1.1 9.4 9.4 6.3 7.0 0.8 3.3 1 1 3 4 4 4 0 RING-variant domain MIEAP PF16026.5 OWF54875.1 - 3.6e-31 108.9 0.1 3.6e-31 108.9 0.1 3.2 2 1 0 3 3 3 1 Mitochondria-eating protein STI1 PF17830.1 OWF54876.1 - 9.1e-07 28.7 0.7 3.6e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 STI1 domain WD40 PF00400.32 OWF54877.1 - 2.7e-46 154.6 19.3 4.6e-08 33.6 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF54877.1 - 4.5e-07 30.1 0.5 0.32 11.3 0.1 5.4 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OWF54877.1 - 3.4e-05 22.8 0.3 0.88 8.2 0.0 3.9 1 1 2 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 OWF54877.1 - 9.7e-05 21.2 1.0 0.14 10.8 0.8 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 OWF54877.1 - 0.021 14.8 0.0 13 5.9 0.0 3.7 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 OWF54877.1 - 0.082 12.2 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain MCM_lid PF17855.1 OWF54878.1 - 1.3e-10 41.5 0.5 2.6e-10 40.6 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM PF00493.23 OWF54878.1 - 1.9e-05 23.9 0.0 3.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain EF-hand_like PF09279.11 OWF54878.1 - 0.024 15.1 0.2 0.081 13.4 0.1 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like PBECR4 PF18813.1 OWF54878.1 - 0.07 13.3 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 DUF2228 PF10228.9 OWF54879.1 - 2.5e-97 325.5 0.7 3.2e-97 325.2 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2228) zf-CCHH PF10283.9 OWF54879.1 - 1.2e-11 44.3 5.5 1.2e-11 44.3 5.5 2.2 3 0 0 3 3 3 1 PBZ domain MADF_DNA_bdg PF10545.9 OWF54880.1 - 0.036 14.4 1.3 0.036 14.4 1.3 1.4 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Strep_SA_rep PF06696.11 OWF54880.1 - 0.17 11.9 7.6 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat CDK5_activator PF03261.15 OWF54881.1 - 4e-106 355.6 12.3 2.7e-100 336.4 3.3 2.0 1 1 1 2 2 2 2 Cyclin-dependent kinase 5 activator protein Myosin_head PF00063.21 OWF54882.1 - 9.9e-243 807.3 3.1 1.3e-242 806.9 3.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OWF54882.1 - 9.4e-43 146.1 0.1 1.7e-42 145.2 0.1 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding DUF5031 PF16434.5 OWF54882.1 - 0.021 14.0 0.1 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5031) AAA_16 PF13191.6 OWF54882.1 - 0.046 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 OWF54882.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 OWF54882.1 - 0.15 12.4 0.1 0.41 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 OWF54882.1 - 3.8 7.6 10.4 0.067 13.0 0.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif HECT PF00632.25 OWF54883.1 - 8.6e-05 22.2 0.1 9.4e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NmrA PF05368.13 OWF54885.1 - 9.4e-46 156.2 0.0 1.2e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OWF54885.1 - 2.3e-17 63.5 0.0 3.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OWF54885.1 - 4.2e-08 33.0 0.2 3.1e-07 30.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OWF54885.1 - 9.5e-07 28.1 0.1 1.4e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OWF54885.1 - 0.0021 18.5 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OWF54885.1 - 0.0039 17.1 0.0 0.0092 15.9 0.0 1.6 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.18 OWF54885.1 - 0.0092 16.2 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain DXP_reductoisom PF02670.16 OWF54885.1 - 0.011 16.4 0.1 0.022 15.4 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glu_dehyd_C PF16912.5 OWF54885.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus adh_short PF00106.25 OWF54885.1 - 0.035 13.5 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 OWF54885.1 - 0.046 13.9 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OWF54885.1 - 0.05 12.8 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 OWF54885.1 - 0.1 12.7 0.1 0.23 11.5 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PALP PF00291.25 OWF54885.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme RFC1 PF08519.12 OWF54886.1 - 6e-61 205.2 0.1 1.2e-60 204.2 0.1 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 OWF54886.1 - 5.7e-16 59.2 0.0 1.3e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 OWF54886.1 - 1.1e-15 57.8 0.0 2.7e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.6 OWF54886.1 - 9.5e-07 29.2 0.0 2.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain PTCB-BRCT PF12738.7 OWF54886.1 - 1e-05 25.4 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain AAA_16 PF13191.6 OWF54886.1 - 2.9e-05 24.5 0.0 9.6e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 OWF54886.1 - 0.00072 19.5 0.2 0.0056 16.6 0.2 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 OWF54886.1 - 0.0032 17.5 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OWF54886.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OWF54886.1 - 0.017 15.3 0.8 0.055 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OWF54886.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 OWF54886.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Pkinase PF00069.25 OWF54887.1 - 2.3e-56 191.1 0.0 3.5e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF54887.1 - 1.3e-24 86.8 0.0 2.1e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 OWF54887.1 - 1.4e-16 60.7 0.0 8e-06 26.1 0.0 4.5 4 0 0 4 4 4 3 PAS domain PAS PF00989.25 OWF54887.1 - 1.3e-06 28.4 0.0 0.004 17.2 0.0 3.2 3 0 0 3 3 3 2 PAS fold Kinase-like PF14531.6 OWF54887.1 - 1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PAS_4 PF08448.10 OWF54887.1 - 0.00085 19.5 0.0 0.26 11.6 0.0 2.9 3 0 0 3 3 3 1 PAS fold Pkinase_fungal PF17667.1 OWF54887.1 - 0.0012 17.7 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PAS_8 PF13188.7 OWF54887.1 - 0.0082 16.1 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 1 PAS domain Haspin_kinase PF12330.8 OWF54887.1 - 0.022 13.7 0.2 0.037 13.0 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OWF54887.1 - 0.031 13.6 0.2 0.06 12.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.12 OWF54887.1 - 0.08 13.2 0.0 0.93 9.8 0.0 2.6 2 0 0 2 2 2 0 PAS fold APH PF01636.23 OWF54887.1 - 0.14 12.1 0.2 0.81 9.6 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3410 PF11890.8 OWF54887.1 - 0.59 10.0 1.9 1.1 9.1 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) DUF4611 PF15387.6 OWF54887.1 - 5.1 7.4 11.7 2.8 8.2 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Exo_endo_phos PF03372.23 OWF54889.1 - 0.00018 21.1 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-bind_4 PF13837.6 OWF54890.1 - 1.6e-06 28.4 3.0 1.6e-06 28.4 3.0 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OWF54890.1 - 2.7e-05 25.0 0.6 2.7e-05 25.0 0.6 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OWF54890.1 - 0.01 15.9 3.6 0.01 15.9 3.6 2.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 OWF54890.1 - 0.042 14.5 4.0 0.2 12.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF573 MADF_DNA_bdg PF10545.9 OWF54890.1 - 0.74 10.2 5.6 0.26 11.6 1.5 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like YHYH PF14240.6 OWF54891.1 - 1.7e-20 73.9 6.7 5.4e-16 59.1 0.1 2.6 2 1 1 3 3 3 2 YHYH protein tify PF06200.14 OWF54892.1 - 0.00095 18.4 0.0 18 4.8 0.0 4.6 5 0 0 5 5 5 2 tify domain DUF5332 PF17266.2 OWF54892.1 - 0.0061 16.3 0.0 12 5.6 0.0 3.2 1 1 3 4 4 4 3 Family of unknown function (DUF5332) DUF4253 PF14062.6 OWF54892.1 - 0.02 15.1 0.1 14 5.9 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4253) DIT1_PvcA PF05141.12 OWF54892.1 - 0.13 11.7 0.0 1.6e+02 1.5 0.0 4.3 2 1 4 6 6 6 0 Pyoverdine/dityrosine biosynthesis protein BTB PF00651.31 OWF54893.1 - 2.4e-12 47.1 0.0 3.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Gar1 PF04410.14 OWF54893.1 - 0.038 13.8 0.4 0.12 12.1 0.4 1.8 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region BTB PF00651.31 OWF54894.1 - 2.7e-17 63.0 0.1 7.1e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 OWF54894.1 - 3e-06 27.4 50.9 0.002 18.5 4.6 6.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF54894.1 - 4.6e-06 26.8 47.1 4.7e-06 26.8 2.4 7.1 7 0 0 7 7 7 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF54894.1 - 2.1e-05 24.1 3.4 2.1e-05 24.1 3.4 3.7 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OWF54894.1 - 0.002 18.8 47.4 0.34 11.9 2.2 6.7 6 0 0 6 6 6 3 C2H2-type zinc finger BAAT_C PF08840.11 OWF54896.1 - 3.7e-32 112.0 0.0 1.9e-31 109.7 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 OWF54896.1 - 9.5e-28 96.8 0.0 2.4e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 OWF54896.1 - 1.5e-07 31.2 0.2 0.0028 17.2 0.0 2.8 3 1 0 3 3 3 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OWF54896.1 - 0.0047 16.4 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ald_Xan_dh_C2 PF02738.18 OWF54897.1 - 2.4e-142 475.2 0.0 3.4e-142 474.7 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 OWF54897.1 - 1.8e-27 95.9 0.0 3.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 OWF54897.1 - 4.1e-23 81.5 0.1 1.2e-22 80.0 0.1 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_5 PF00941.21 OWF54897.1 - 2.4e-21 76.2 0.0 4.5e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OWF54897.1 - 4.8e-21 74.6 0.2 1.3e-20 73.2 0.2 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 OWF54897.1 - 3e-05 23.9 0.0 0.00012 22.0 0.0 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PCYCGC PF13798.6 OWF54897.1 - 0.00061 19.7 0.3 0.0014 18.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function with PCYCGC motif Fer2_4 PF13510.6 OWF54897.1 - 0.01 15.8 0.1 0.032 14.3 0.1 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-HC3 PF16827.5 OWF54897.1 - 0.021 15.0 1.3 0.12 12.6 0.3 2.7 2 0 0 2 2 2 0 zinc-finger DUF1223 PF06764.11 OWF54897.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) PXA PF02194.15 OWF54898.1 - 2.2e-37 128.8 0.2 8e-37 127.0 0.0 2.1 2 0 0 2 2 2 1 PXA domain PX PF00787.24 OWF54898.1 - 4e-17 62.2 0.9 1.5e-16 60.4 0.0 2.5 3 0 0 3 3 3 1 PX domain Nexin_C PF08628.12 OWF54898.1 - 4.9e-16 59.3 0.1 1.1e-15 58.1 0.1 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal RGS PF00615.19 OWF54898.1 - 5.8e-13 49.2 0.2 1.5e-12 47.8 0.2 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Syncollin PF15138.6 OWF54898.1 - 0.072 13.3 0.2 4.7 7.5 0.1 2.5 2 0 0 2 2 2 0 Syncollin BCL9 PF11502.8 OWF54900.1 - 9.3e-09 34.9 6.3 1.3e-07 31.3 6.3 3.2 1 0 0 1 1 1 1 B-cell lymphoma 9 protein Bac_globin PF01152.21 OWF54900.1 - 5.8 7.1 10.3 14 5.9 0.3 4.2 3 1 1 4 4 4 0 Bacterial-like globin MCM PF00493.23 OWF54901.1 - 7.5e-90 299.9 0.0 1e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 OWF54901.1 - 7.8e-28 96.7 1.4 1.6e-27 95.7 1.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OWF54901.1 - 4.5e-26 91.2 0.9 7.9e-26 90.4 0.9 1.3 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 OWF54901.1 - 1.1e-09 38.0 0.1 3.6e-06 26.5 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF54901.1 - 1.3e-09 38.2 0.0 2.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OWF54901.1 - 0.0001 22.1 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF54901.1 - 0.0065 16.9 0.0 0.052 13.9 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 OWF54901.1 - 0.0069 16.1 0.0 0.038 13.7 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF1834 PF08873.11 OWF54901.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) FtsK_SpoIIIE PF01580.18 OWF54901.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SEP PF08059.13 OWF54902.1 - 4e-26 91.4 1.0 1.6e-25 89.5 0.2 2.2 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 OWF54902.1 - 9.9e-14 51.3 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OWF54902.1 - 1.7e-13 50.2 0.2 2.8e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 OWF54902.1 - 0.00085 18.9 0.2 0.0028 17.3 0.0 1.9 2 0 0 2 2 2 1 TAP C-terminal domain Glyco_transf_11 PF01531.16 OWF54905.1 - 0.0031 16.8 0.3 0.0066 15.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 11 O-FucT PF10250.9 OWF54905.1 - 0.0038 17.0 0.3 0.0068 16.2 0.1 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Myb_DNA-bind_5 PF13873.6 OWF54905.1 - 0.047 13.8 0.1 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Sulfotransfer_1 PF00685.27 OWF54906.1 - 1e-46 159.6 1.5 6.5e-46 157.0 1.5 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF54906.1 - 1.2e-06 29.1 0.2 1.4e-05 25.6 0.3 2.2 1 1 0 2 2 2 1 Sulfotransferase family GH43_C PF16369.5 OWF54906.1 - 0.063 13.9 0.2 0.14 12.8 0.2 1.5 1 0 0 1 1 1 0 C-terminal lipocalin-like domain FARP PF01581.16 OWF54907.1 - 2.3e-42 135.1 216.1 0.19 12.3 1.0 27.6 26 2 1 27 27 27 26 FMRFamide related peptide family Laminin_N PF00055.17 OWF54908.1 - 7.7e-83 277.7 1.7 7.7e-83 277.7 1.7 3.5 4 0 0 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 OWF54908.1 - 8.7e-76 249.9 232.8 2.9e-11 43.3 13.9 12.3 13 0 0 13 13 13 11 Laminin EGF domain Laminin_B PF00052.18 OWF54908.1 - 2.2e-29 102.0 0.0 4.7e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) Staph_haemo PF05480.11 OWF54909.1 - 1.3 8.8 4.4 60 3.5 0.1 3.8 3 1 0 4 4 4 0 Staphylococcus haemolytic protein Cytochrom_B561 PF03188.16 OWF54909.1 - 2.1 8.5 12.4 8.8e+02 -0.0 12.4 3.3 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 COX8 PF02285.15 OWF54910.1 - 0.035 14.0 4.8 14 5.6 0.1 4.4 1 1 4 5 5 5 0 Cytochrome oxidase c subunit VIII Cytochrom_B561 PF03188.16 OWF54910.1 - 2.2 8.4 13.6 2e+02 2.1 13.6 3.0 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 COX8 PF02285.15 OWF54912.1 - 0.0066 16.3 32.0 2.3 8.2 0.1 11.4 4 3 9 15 15 15 6 Cytochrome oxidase c subunit VIII 7tm_1 PF00001.21 OWF54913.1 - 4.9e-19 68.7 25.7 6.2e-19 68.3 25.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2600 PF10776.9 OWF54913.1 - 0.11 11.4 0.1 0.57 9.0 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2600) RNase_J_C PF17770.1 OWF54914.1 - 1.6e-18 67.5 0.0 4.6e+02 1.9 0.0 23.8 24 6 5 29 29 29 0 Ribonuclease J C-terminal domain BIR PF00653.21 OWF54914.1 - 2.6e-17 63.2 44.4 64 4.3 0.1 28.0 7 6 10 17 17 17 0 Inhibitor of Apoptosis domain Mucin-like PF16058.5 OWF54914.1 - 1e-09 38.3 0.0 13 6.0 0.0 7.8 4 4 4 8 8 8 3 Mucin-like Hema_stalk PF08720.10 OWF54914.1 - 0.00033 20.4 0.0 1e+02 2.5 0.0 8.2 8 1 0 8 8 8 0 Influenza C hemagglutinin stalk DUF3368 PF11848.8 OWF54914.1 - 0.0013 18.5 32.5 2.4e+02 1.6 0.0 20.1 21 8 5 33 33 33 0 Domain of unknown function (DUF3368) 7tm_1 PF00001.21 OWF54915.1 - 3.5e-25 88.8 29.8 3.5e-25 88.8 29.8 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Baculo_11_kDa PF06143.11 OWF54915.1 - 0.04 13.5 0.3 0.04 13.5 0.3 3.5 3 1 1 4 4 4 0 Baculovirus 11 kDa family TMEM154 PF15102.6 OWF54915.1 - 0.37 10.7 4.4 12 5.8 0.6 2.7 2 0 0 2 2 2 0 TMEM154 protein family MnhB PF04039.13 OWF54915.1 - 4.3 7.7 11.2 1.9 8.8 1.6 2.7 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter TSP_1 PF00090.19 OWF54916.1 - 2.7e-09 37.1 1.6 2.7e-09 37.1 1.6 3.0 3 1 0 3 3 3 1 Thrombospondin type 1 domain Coilin_N PF15862.5 OWF54917.1 - 0.013 15.3 0.6 1.4 8.7 0.6 3.0 1 1 0 1 1 1 0 Coilin N-terminus DUF5000 PF16391.5 OWF54917.1 - 0.071 13.2 0.3 18 5.5 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function DUF5514 PF17633.2 OWF54917.1 - 2.5 8.3 13.8 2.9 8.1 0.7 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5514) RhoGEF PF00621.20 OWF54918.1 - 2.3e-40 138.8 1.0 4.7e-40 137.8 1.0 1.6 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.31 OWF54918.1 - 9.2e-21 74.1 0.1 2e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain SH3_1 PF00018.28 OWF54918.1 - 3.7e-17 61.7 0.2 2.1e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 OWF54918.1 - 5.5e-17 61.6 0.0 1.7e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 OWF54918.1 - 5.4e-16 58.0 0.1 1.5e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain CAMSAP_CH PF11971.8 OWF54918.1 - 3.2e-15 55.7 0.1 6.9e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain SH3_9 PF14604.6 OWF54918.1 - 1.1e-13 50.8 0.0 2.2e-09 37.0 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PH PF00169.29 OWF54918.1 - 4e-10 40.1 3.1 5.6e-10 39.7 0.3 2.6 3 0 0 3 3 3 1 PH domain PH_10 PF15411.6 OWF54918.1 - 2.1e-05 24.8 0.1 6.7e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 OWF54918.1 - 0.00036 20.7 0.2 0.0011 19.2 0.0 1.9 2 0 0 2 2 1 1 CDC24 Calponin C1_1 PF00130.22 OWF54918.1 - 0.0015 18.3 0.5 0.0039 17.0 0.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) IQ_SEC7_PH PF16453.5 OWF54918.1 - 0.0085 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 OWF54918.1 - 0.062 13.1 0.2 0.4 10.5 0.2 2.2 1 1 0 1 1 1 0 PH domain TDRP PF15683.5 OWF54918.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Testis development-related protein DUF2451 PF10474.9 OWF54918.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) PH_13 PF16652.5 OWF54918.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain CH_2 PF06294.11 OWF54918.1 - 0.13 12.4 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 CH-like domain in sperm protein Abhydrolase_5 PF12695.7 OWF54919.1 - 0.017 14.9 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kelch_4 PF13418.6 OWF54920.1 - 2.1e-31 107.7 6.8 5.9e-07 29.4 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF54920.1 - 9.6e-30 101.4 7.0 6.1e-08 32.3 0.2 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 OWF54920.1 - 1.1e-28 98.6 2.0 2.8e-05 23.6 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 OWF54920.1 - 2.9e-28 97.3 10.7 2.1e-06 27.6 0.0 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 OWF54920.1 - 3.8e-26 90.8 7.6 1.7e-08 34.5 0.1 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OWF54920.1 - 9.1e-24 82.9 6.7 7e-05 23.0 0.0 5.6 4 1 1 5 5 5 5 Kelch motif Rad51 PF08423.11 OWF54921.1 - 6.4e-08 32.2 0.0 3.6e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OWF54921.1 - 2.1e-05 24.2 0.0 5.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OWF54921.1 - 0.0061 17.0 0.0 0.057 13.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OWF54921.1 - 0.03 14.2 0.2 0.062 13.2 0.2 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea WD40 PF00400.32 OWF54922.1 - 2.5e-23 81.9 3.1 0.01 16.7 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 OWF54922.1 - 4.2e-14 52.1 11.6 8.5e-14 51.1 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF54922.1 - 3.3e-10 39.7 12.9 8.8e-10 38.3 12.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF54922.1 - 5.4e-09 35.8 8.0 5.4e-09 35.8 8.0 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF54922.1 - 6.4e-09 35.7 8.5 1.6e-08 34.4 8.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF54922.1 - 1.2e-08 35.2 10.4 3.5e-08 33.6 10.4 1.9 1 0 0 1 1 1 1 Ring finger domain ANAPC4_WD40 PF12894.7 OWF54922.1 - 4.4e-08 33.3 0.4 0.54 10.6 0.0 4.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 OWF54922.1 - 1.7e-07 31.1 11.6 1.7e-07 31.1 11.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain WD40_like PF17005.5 OWF54922.1 - 5.4e-07 29.2 0.0 3.3e-06 26.7 0.1 2.1 1 1 1 2 2 2 1 WD40-like domain zf-C3HC4_4 PF15227.6 OWF54922.1 - 1.1e-06 28.7 10.7 2.9e-06 27.4 10.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OWF54922.1 - 0.0052 17.1 10.1 0.0052 17.1 10.1 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OWF54922.1 - 0.0057 16.8 4.2 0.017 15.2 4.2 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OWF54922.1 - 0.0096 15.8 10.1 0.092 12.6 10.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OWF54922.1 - 0.063 13.1 9.4 0.21 11.4 9.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain bZIP_1 PF00170.21 OWF54922.1 - 0.14 12.3 0.7 0.47 10.6 0.7 1.9 1 0 0 1 1 1 0 bZIP transcription factor zf-RING_6 PF14835.6 OWF54922.1 - 0.43 10.5 2.8 0.97 9.4 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 OWF54922.1 - 0.92 9.2 7.5 4 7.2 7.5 2.1 1 1 0 1 1 1 0 P-11 zinc finger DUF1272 PF06906.11 OWF54922.1 - 1 9.5 6.8 3 8.0 6.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 OWF54922.1 - 1.1 9.3 7.8 3.1 7.9 7.8 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_11 PF17123.5 OWF54922.1 - 1.4 8.7 9.0 4.8 7.0 9.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 OWF54922.1 - 4.5 7.2 9.9 1.6 8.6 6.3 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OWF54922.1 - 6.8 6.8 7.9 6.3 6.9 3.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4024 PF13216.6 OWF54923.1 - 5.1e-18 64.5 24.2 2.1 8.4 0.1 17.4 2 2 19 21 21 21 6 Protein of unknown function (DUF4024) GLF PF03275.13 OWF54923.1 - 1.3e-06 28.2 5.8 1.4 8.6 0.1 5.2 1 1 3 5 5 5 4 UDP-galactopyranose mutase Ribosomal_S4 PF00163.19 OWF54923.1 - 0.00038 21.3 8.2 26 5.8 0.1 7.4 3 2 4 8 8 8 0 Ribosomal protein S4/S9 N-terminal domain DUF4132 PF13569.6 OWF54923.1 - 0.00075 19.3 7.1 9.3 6.0 0.2 7.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4132) SCAB-PH PF17684.1 OWF54923.1 - 0.0016 18.7 0.0 50 4.2 0.0 5.3 3 2 2 6 6 6 0 PH domain of plant-specific actin-binding protein Top6b_C PF18000.1 OWF54923.1 - 0.0059 16.8 7.5 61 3.8 0.1 6.3 1 1 8 9 9 9 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Cas_VVA1548 PF09652.10 OWF54923.1 - 0.047 13.9 20.7 22 5.4 0.2 7.0 1 1 8 9 9 9 0 Putative CRISPR-associated protein (Cas_VVA1548) DUF4384 PF14326.6 OWF54923.1 - 0.058 13.5 15.2 78 3.5 0.1 7.8 1 1 7 8 8 8 0 Domain of unknown function (DUF4384) CTP-dep_RFKase PF01982.16 OWF54923.1 - 1.7 8.8 28.3 4.7 7.3 0.6 6.2 1 1 7 8 8 8 0 Domain of unknown function DUF120 HEV_ORF1 PF02444.16 OWF54925.1 - 0.016 15.8 7.3 57 4.3 0.0 5.9 2 1 8 10 10 10 0 Hepatitis E virus ORF-2 (Putative capsid protein) Molydop_binding PF01568.21 OWF54925.1 - 1.7 8.7 5.2 1.1e+02 2.9 0.0 4.2 4 0 0 4 4 4 0 Molydopterin dinucleotide binding domain ATS3 PF06232.11 OWF54926.1 - 0.0066 16.4 15.5 11 6.0 0.1 5.5 1 1 2 4 4 4 4 Embryo-specific protein 3, (ATS3) PNP_UDP_1 PF01048.20 OWF54927.1 - 1.7e-25 89.7 0.0 2.1e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily CH_2 PF06294.11 OWF54928.1 - 9.8e-05 22.4 1.2 1.1 9.4 0.1 3.2 1 1 2 3 3 3 2 CH-like domain in sperm protein UPF0228 PF05727.11 OWF54928.1 - 0.0014 18.4 0.6 0.87 9.4 0.6 3.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0228) SH3_1 PF00018.28 OWF54928.1 - 0.0037 16.9 0.2 62 3.3 0.0 4.7 2 2 4 6 6 6 0 SH3 domain Branch PF02485.21 OWF54928.1 - 0.01 15.3 0.0 2.7 7.4 0.0 3.5 1 1 1 2 2 2 0 Core-2/I-Branching enzyme YqbF PF14553.6 OWF54928.1 - 0.013 15.4 7.5 8.4 6.3 0.4 4.2 1 1 3 4 4 4 0 YqbF, hypothetical protein domain Aldo_ket_red PF00248.21 OWF54928.1 - 0.035 13.3 1.3 0.3 10.3 0.8 1.9 1 1 0 1 1 1 0 Aldo/keto reductase family DUF3642 PF12182.8 OWF54928.1 - 0.06 13.6 0.1 13 6.1 0.0 2.3 1 1 2 3 3 3 0 Bacterial lipoprotein Nuc_N PF14448.6 OWF54928.1 - 0.12 12.2 5.2 95 3.0 0.0 5.4 2 2 5 7 7 7 0 Nuclease N terminal Thg1C PF14413.6 OWF54928.1 - 0.13 12.4 5.9 12 6.1 1.3 3.6 1 1 2 3 3 3 0 Thg1 C terminal domain Med18 PF09637.10 OWF54928.1 - 0.2 11.4 5.5 3.3 7.5 0.5 2.5 1 1 1 2 2 2 0 Med18 protein PNMA PF14893.6 OWF54928.1 - 0.84 9.0 2.4 37 3.6 0.2 3.1 1 1 2 3 3 3 0 PNMA zf-C2H2 PF00096.26 OWF54930.1 - 0.0017 18.7 0.1 0.0017 18.7 0.1 2.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF54930.1 - 0.014 16.2 0.1 0.014 16.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF54930.1 - 0.21 11.9 0.4 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF54930.1 - 1.6 8.8 4.0 5 7.2 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Ephrin_rec_like PF07699.13 OWF54931.1 - 1.9e-130 424.5 242.3 2.5e-11 43.1 6.3 19.9 19 1 0 19 19 19 16 Putative ephrin-receptor like EGF PF00008.27 OWF54931.1 - 8.1e-47 157.1 229.7 4.7e-06 26.8 4.7 19.7 18 0 0 18 18 18 13 EGF-like domain hEGF PF12661.7 OWF54931.1 - 2.2e-29 101.0 196.7 1.9e-05 25.1 5.6 19.1 17 0 0 17 17 17 12 Human growth factor-like EGF Laminin_G_3 PF13385.6 OWF54931.1 - 1.8e-07 31.5 1.6 3.7e-07 30.4 1.6 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily HYR PF02494.16 OWF54931.1 - 4.4e-05 23.7 0.0 0.00027 21.2 0.0 2.5 1 0 0 1 1 1 1 HYR domain EGF_CA PF07645.15 OWF54931.1 - 0.0002 21.5 10.7 0.0002 21.5 10.7 26.5 22 8 7 29 29 29 7 Calcium-binding EGF domain Laminin_G_2 PF02210.24 OWF54931.1 - 0.00063 20.3 0.2 0.0012 19.4 0.2 1.5 1 0 0 1 1 1 1 Laminin G domain DUF1120 PF06551.12 OWF54931.1 - 0.0021 18.2 0.0 0.0068 16.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1120) NCD3G PF07562.14 OWF54931.1 - 5.5 7.0 214.2 0.029 14.3 1.3 21.9 13 6 5 20 20 20 0 Nine Cysteines Domain of family 3 GPCR DUF913 PF06025.12 OWF54932.1 - 0.095 11.7 1.3 0.11 11.5 1.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 OWF54932.1 - 0.5 8.6 8.9 0.53 8.5 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 OWF54932.1 - 2 8.2 13.8 2.6 7.9 4.5 2.1 2 0 0 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 OWF54932.1 - 2.3 6.9 5.9 2.6 6.7 5.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 OWF54932.1 - 4.2 8.4 8.0 11 7.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rxt3 PF08642.10 OWF54932.1 - 5.4 7.8 9.3 0.38 11.5 0.5 2.0 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 SRP72 PF08492.12 OWF54932.1 - 6.2 7.3 16.2 2.6 8.6 4.2 2.3 2 0 0 2 2 2 0 SRP72 RNA-binding domain MFS_1_like PF12832.7 OWF54933.1 - 1.8e-83 280.5 13.9 2.3e-83 280.2 13.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OWF54933.1 - 1.9e-17 63.2 34.3 2.1e-08 33.5 24.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 OWF54933.1 - 1.3e-07 30.8 22.6 8.2e-06 24.8 1.4 3.9 2 1 1 3 3 3 2 LacY proton/sugar symporter Nuc_H_symport PF03825.16 OWF54933.1 - 1e-06 28.0 20.9 0.0004 19.5 17.3 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter MFS_2 PF13347.6 OWF54933.1 - 7.3e-06 24.8 25.2 0.0048 15.5 1.3 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein PROCT PF08084.11 OWF54933.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 PROCT (NUC072) domain ATG22 PF11700.8 OWF54933.1 - 0.066 11.8 0.1 0.066 11.8 0.1 3.3 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like MtrG PF04210.13 OWF54933.1 - 1.2 9.1 3.2 13 5.7 0.4 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4027 PF13219.6 OWF54934.1 - 0.66 9.9 19.4 7.6 6.5 0.0 7.5 9 0 0 9 9 9 0 Protein of unknown function (DUF4027) zf-CXXC PF02008.20 OWF54936.1 - 9.2e-07 28.8 20.9 9.2e-07 28.8 20.9 1.8 2 0 0 2 2 2 1 CXXC zinc finger domain GST_N_3 PF13417.6 OWF54937.1 - 4.8e-18 65.3 0.0 1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF54937.1 - 6.4e-18 64.8 0.1 5.1e-17 61.9 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF54937.1 - 6.5e-10 39.2 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OWF54937.1 - 1.4e-05 25.6 0.0 2.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF54937.1 - 2.5e-05 24.2 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF54937.1 - 0.016 15.4 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OWF54937.1 - 0.059 13.6 0.0 0.48 10.7 0.0 2.4 2 1 0 2 2 2 0 Glutaredoxin Fer4_5 PF12801.7 OWF54937.1 - 0.32 11.0 2.5 1 9.3 2.5 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain Asp PF00026.23 OWF54938.1 - 4.8e-104 348.2 0.8 9.9e-103 343.9 0.8 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OWF54938.1 - 8.4e-14 52.2 1.4 6e-12 46.2 1.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OWF54938.1 - 8.4e-05 22.4 0.0 0.00021 21.1 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OWF54938.1 - 0.00035 21.2 0.2 0.033 14.8 0.1 3.1 2 1 0 2 2 2 1 Aspartyl protease A1_Propeptide PF07966.12 OWF54938.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 A1 Propeptide Sdh5 PF03937.16 OWF54939.1 - 4.3e-25 87.5 0.1 6.1e-25 87.0 0.1 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase EF-hand_1 PF00036.32 OWF54940.1 - 1.1e-23 81.0 12.1 8.2e-05 21.9 0.1 6.3 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 OWF54940.1 - 3.2e-19 67.1 10.9 0.00029 20.5 0.1 5.9 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 OWF54940.1 - 5.6e-17 61.9 30.0 7.6e-10 39.1 4.3 3.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF54940.1 - 5.3e-16 57.3 20.9 0.00057 19.3 0.7 5.5 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 OWF54940.1 - 1.6e-09 37.5 10.9 0.39 10.6 0.1 5.4 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_10 PF14788.6 OWF54940.1 - 0.0034 17.2 2.2 6.4 6.7 0.1 4.0 4 0 0 4 4 4 2 EF hand Spa1_C PF18218.1 OWF54940.1 - 0.0078 16.6 1.0 0.021 15.2 0.1 2.3 2 0 0 2 2 2 1 Lantibiotic immunity protein Spa1 C-terminal domain SPARC_Ca_bdg PF10591.9 OWF54940.1 - 0.39 11.1 20.7 0.89 9.9 3.9 3.5 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Ank_4 PF13637.6 OWF54941.1 - 2.9e-17 62.8 0.0 8.1e-08 32.7 0.0 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF54941.1 - 2.6e-14 53.6 0.0 1.7e-06 28.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF54941.1 - 5.8e-12 45.5 0.0 3.4e-06 27.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OWF54941.1 - 1.4e-11 44.3 0.1 1.2e-06 28.7 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF54941.1 - 5.3e-11 41.7 0.1 7e-06 26.0 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeat RIFIN PF02009.16 OWF54941.1 - 0.32 10.9 0.1 0.47 10.3 0.1 1.2 1 0 0 1 1 1 0 Rifin IBN_N PF03810.19 OWF54942.1 - 8.1e-18 64.1 0.2 2.5e-16 59.4 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OWF54942.1 - 1.6e-07 31.5 0.1 1.6e-07 31.5 0.1 4.2 5 1 0 5 5 5 1 Exportin 1-like protein Cse1 PF08506.10 OWF54942.1 - 1.8e-05 23.7 1.6 1.8e-05 23.7 1.6 3.2 3 0 0 3 3 3 1 Cse1 RIX1 PF08167.12 OWF54942.1 - 0.024 14.4 7.1 2.6 7.7 0.2 4.4 3 2 1 4 4 4 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 OWF54942.1 - 0.064 13.4 0.3 2.2 8.5 0.3 3.6 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 FliS PF02561.14 OWF54942.1 - 0.077 13.3 0.5 5.7 7.3 0.3 3.1 2 0 0 2 2 2 0 Flagellar protein FliS DUF1765 PF08578.10 OWF54942.1 - 0.55 10.7 4.3 2.7 8.5 0.1 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1765) SDA1 PF05285.12 OWF54942.1 - 2.7 7.3 16.5 4.3 6.7 16.5 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OWF54942.1 - 5.1 5.3 11.6 8.3 4.6 11.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Synaptobrevin PF00957.21 OWF54943.1 - 5.1e-31 106.3 2.4 5.6e-31 106.2 2.4 1.0 1 0 0 1 1 1 1 Synaptobrevin BLOC1_2 PF10046.9 OWF54943.1 - 0.0037 17.5 1.3 0.0042 17.3 1.3 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_teg_N PF04843.12 OWF54943.1 - 0.039 13.7 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region MCU PF04678.13 OWF54943.1 - 0.047 13.8 0.1 0.049 13.7 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter COG5 PF10392.9 OWF54943.1 - 0.053 13.7 0.4 0.066 13.4 0.4 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 LMBR1 PF04791.16 OWF54943.1 - 0.056 12.4 0.3 0.058 12.3 0.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 OWF54943.1 - 0.93 9.3 4.9 7.4 6.4 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator UPF0258 PF06789.12 OWF54943.1 - 4.3 7.5 6.7 4.2 7.5 6.4 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) zf-NOSIP PF15906.5 OWF54944.1 - 2.8e-18 65.8 1.1 6.7e-18 64.6 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 OWF54944.1 - 1.6e-10 40.8 13.5 2.1e-06 27.3 0.1 2.9 1 1 2 3 3 3 2 Rtf2 RING-finger U-box PF04564.15 OWF54944.1 - 8.5e-07 29.1 0.0 0.017 15.3 0.0 2.4 2 0 0 2 2 2 2 U-box domain zf-Nse PF11789.8 OWF54944.1 - 0.012 15.4 1.3 0.13 12.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF45 PF01863.17 OWF54944.1 - 0.016 15.3 0.4 0.026 14.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF3138 PF11336.8 OWF54944.1 - 2.2 6.8 4.0 3.2 6.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF775 PF05603.12 OWF54945.1 - 4.3e-58 196.1 1.9 6.7e-58 195.5 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) PP1 PF07430.11 OWF54946.1 - 0.011 15.8 1.0 75 3.5 0.0 4.2 1 1 4 5 5 5 0 Phloem filament protein PP1 cystatin-like domain Bac_small_YrzI PF09501.10 OWF54946.1 - 0.04 14.0 0.3 7.1 6.8 0.0 2.7 1 1 1 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DUF3568 PF12092.8 OWF54946.1 - 0.055 13.5 1.4 2.1 8.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3568) DUF1192 PF06698.11 OWF54946.1 - 0.097 12.7 0.1 7.3 6.7 0.0 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1192) VWA PF00092.28 OWF54947.1 - 7.4e-18 65.4 0.0 7.4e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF54947.1 - 2.1e-09 37.4 28.1 3e-07 30.5 6.7 3.7 3 1 1 4 4 4 2 Chitin binding Peritrophin-A domain SIKE PF05769.11 OWF54948.1 - 2.7e-68 229.5 20.3 3.7e-68 229.0 20.3 1.2 1 0 0 1 1 1 1 SIKE family TolA_bind_tri PF16331.5 OWF54948.1 - 0.006 16.6 11.1 0.006 16.6 11.1 3.7 2 1 2 4 4 4 1 TolA binding protein trimerisation DUF1479 PF07350.12 OWF54948.1 - 0.022 13.5 2.9 0.031 13.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) HpaP PF09483.10 OWF54948.1 - 0.11 12.8 0.4 0.11 12.8 0.4 2.6 4 0 0 4 4 4 0 Type III secretion protein (HpaP) FTA4 PF13093.6 OWF54948.1 - 0.65 9.8 11.8 1.7 8.5 11.5 1.6 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DHHA1 PF02272.19 OWF54948.1 - 1.2 9.5 5.8 0.67 10.4 2.5 2.2 2 1 0 2 2 2 0 DHHA1 domain DUF4600 PF15372.6 OWF54948.1 - 1.2 9.5 15.2 1.1 9.6 8.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) RecG_N PF17190.4 OWF54948.1 - 1.3 9.8 9.0 2.8 8.7 0.1 3.4 1 1 2 4 4 4 0 RecG N-terminal helical domain LON_substr_bdg PF02190.16 OWF54948.1 - 2.6 7.9 7.1 0.92 9.3 3.6 1.9 1 1 1 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain CotJB PF12652.7 OWF54948.1 - 2.9 8.2 6.1 5.4 7.3 0.1 3.0 3 0 0 3 3 3 0 CotJB protein NYD-SP28_assoc PF14775.6 OWF54948.1 - 3 8.0 15.1 6.8 6.9 0.1 4.0 3 1 0 4 4 4 0 Sperm tail C-terminal domain Trypsin_2 PF13365.6 OWF54949.1 - 0.0065 17.4 0.0 0.015 16.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain EMG1 PF03587.14 OWF54949.1 - 0.04 13.6 2.2 0.06 13.0 0.1 2.3 2 0 0 2 2 2 0 EMG1/NEP1 methyltransferase MobL PF18555.1 OWF54949.1 - 0.062 12.5 4.4 0.048 12.9 2.2 1.8 1 1 0 1 1 1 0 MobL relaxases DUF1289 PF06945.13 OWF54949.1 - 0.062 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) RNase_PH_C PF03725.15 OWF54949.1 - 0.063 13.3 0.1 0.26 11.3 0.1 2.1 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF4745 PF15923.5 OWF54949.1 - 0.078 13.0 0.3 0.19 11.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) DUF2508 PF10704.9 OWF54949.1 - 4.8 7.4 7.3 6.2 7.1 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) VSP PF03302.13 OWF54950.1 - 0.046 12.6 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Mab-21 PF03281.14 OWF54951.1 - 1.1e-26 93.9 1.7 1.8e-26 93.1 1.7 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_1 PF00515.28 OWF54951.1 - 0.0024 17.6 0.0 0.0074 16.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OWF54951.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF54951.1 - 0.026 14.8 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat IFT46_B_C PF12317.8 OWF54951.1 - 0.085 12.6 0.3 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal TPR_2 PF07719.17 OWF54951.1 - 0.091 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 OWF54951.1 - 0.1 12.9 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RVP_2 PF08284.11 OWF54952.1 - 0.0018 18.1 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OWF54952.1 - 0.013 16.1 0.1 0.62 10.7 0.1 2.4 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Lar_N PF09861.9 OWF54952.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Astacin PF01400.24 OWF54953.1 - 3.8e-54 183.2 0.1 5.4e-54 182.7 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Lectin_C PF00059.21 OWF54953.1 - 2.4e-06 28.3 0.0 4.3e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Lectin C-type domain CUB PF00431.20 OWF54953.1 - 3.4e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 CUB domain Peptidase_M66 PF10462.9 OWF54953.1 - 0.0041 16.1 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 UL45 PF05473.12 OWF54953.1 - 0.027 14.1 0.1 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Reprolysin_4 PF13583.6 OWF54953.1 - 0.03 14.0 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OWF54953.1 - 0.035 14.0 0.3 0.19 11.5 0.1 2.0 1 1 0 2 2 2 0 Matrixin Reprolysin_3 PF13582.6 OWF54953.1 - 0.077 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF54953.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Frag1 PF10277.9 OWF54954.1 - 1.2e-20 74.0 6.4 1.6e-20 73.6 6.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4190 PF13828.6 OWF54954.1 - 0.017 14.8 0.3 0.017 14.8 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) PH_3 PF14593.6 OWF54955.1 - 0.00013 22.0 0.0 1.1 9.4 0.0 4.2 2 2 1 4 4 4 1 PH domain Big_3_2 PF12245.8 OWF54955.1 - 0.00024 21.4 0.3 16 5.8 0.0 4.1 1 1 4 5 5 5 2 Bacterial Ig-like domain Mur_ligase_C PF02875.21 OWF54955.1 - 0.018 15.3 2.9 84 3.5 0.0 5.1 1 1 5 6 6 6 0 Mur ligase family, glutamate ligase domain Cu_bind_like PF02298.17 OWF54955.1 - 0.049 13.6 0.2 2.9 8.0 0.0 3.4 1 1 4 5 5 5 0 Plastocyanin-like domain Arteri_nucleo PF01481.16 OWF54955.1 - 0.82 10.0 2.8 47 4.3 0.0 4.1 1 1 1 5 5 5 0 Arterivirus nucleocapsid protein UBA_6 PF18039.1 OWF54955.1 - 1.2 9.1 6.9 16 5.5 0.1 4.5 5 1 0 5 5 5 0 UBA-like domain Frag1 PF10277.9 OWF54956.1 - 5.1e-18 65.4 9.4 6.1e-18 65.2 9.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Phage_holin_3_3 PF16083.5 OWF54956.1 - 0.012 15.7 1.8 0.034 14.3 1.4 2.0 1 1 0 1 1 1 0 LydA holin phage, holin superfamily III TssN PF17555.2 OWF54956.1 - 0.018 14.4 2.9 0.029 13.8 2.9 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF998 PF06197.13 OWF54956.1 - 0.026 14.1 6.7 0.042 13.4 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF3671 PF12420.8 OWF54956.1 - 0.075 13.1 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function ECF_trnsprt PF12822.7 OWF54956.1 - 0.25 11.4 6.6 0.47 10.5 6.7 1.4 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF4199 PF13858.6 OWF54956.1 - 2.2 8.7 9.4 0.93 9.9 6.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) MNHE PF01899.16 OWF54956.1 - 2.3 8.0 6.7 1.1e+02 2.6 6.7 2.7 1 1 0 1 1 1 0 Na+/H+ ion antiporter subunit Fibrinogen_BP PF08017.11 OWF54957.1 - 2.5e-12 46.0 8.4 3.1e-12 45.6 8.4 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein MIB_HERC2 PF06701.13 OWF54957.1 - 0.63 10.3 2.9 1.6e+02 2.7 2.9 3.5 1 1 0 1 1 1 0 Mib_herc2 DGF-1_4 PF11024.8 OWF54957.1 - 3.6 8.5 11.9 98 3.9 0.3 5.0 1 1 7 8 8 8 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 TRI5 PF06330.11 OWF54958.1 - 0.08 11.8 0.3 0.15 10.9 0.2 1.4 1 1 0 1 1 1 0 Trichodiene synthase (TRI5) KAP_NTPase PF07693.14 OWF54958.1 - 1.1 8.4 4.1 1.5 8.0 4.1 1.3 1 1 0 1 1 1 0 KAP family P-loop domain KaiB PF07689.12 OWF54959.1 - 2.7e-24 84.7 53.5 1.7 8.4 0.2 17.9 1 1 33 34 34 34 34 KaiB domain Acetyltransf_2 PF00797.17 OWF54959.1 - 1.5e-07 31.5 24.7 3 7.6 0.8 7.7 1 1 8 9 9 9 9 N-acetyltransferase Sulfotransfer_1 PF00685.27 OWF54960.1 - 6.7e-52 176.6 1.4 3.5e-50 170.9 1.4 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF54960.1 - 5.2e-05 23.7 0.0 0.00015 22.2 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Orf78 PF06024.12 OWF54961.1 - 0.0065 16.7 38.1 63 3.9 0.3 15.2 6 3 16 22 22 22 2 Orf78 (ac78) PhoQ_Sensor PF08918.10 OWF54961.1 - 5 6.9 34.9 58 3.5 0.2 11.5 3 3 9 14 14 14 0 PhoQ Sensor AMP-binding PF00501.28 OWF54962.1 - 8e-97 324.5 0.0 1e-96 324.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF54962.1 - 5.6e-15 56.1 0.4 1.1e-14 55.1 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3767 PF12597.8 OWF54962.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) GTP-bdg_N PF13167.6 OWF54963.1 - 7e-13 49.1 0.0 1.8e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 OWF54963.1 - 1.3e-05 25.7 0.1 5.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 GTP-binding GTPase Middle Region LIM PF00412.22 OWF54964.1 - 1.4e-08 34.9 4.7 2.6e-08 34.0 4.7 1.5 1 0 0 1 1 1 1 LIM domain Paramyxo_ncap PF00973.19 OWF54965.1 - 6.3 5.6 9.4 9.9 5.0 9.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein L27 PF02828.16 OWF54966.1 - 4.9e-22 77.4 0.5 1.6e-21 75.8 0.1 1.9 2 0 0 2 2 2 1 L27 domain PDZ PF00595.24 OWF54966.1 - 4.5e-18 65.4 0.2 7e-18 64.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF54966.1 - 2.2e-11 43.4 0.3 6.7e-11 41.9 0.1 1.9 2 0 0 2 2 2 1 PDZ domain DUF2057 PF09829.9 OWF54966.1 - 0.0033 17.6 0.3 0.027 14.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) PDZ_2 PF13180.6 OWF54966.1 - 0.0085 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DED PF01335.21 OWF54966.1 - 0.042 14.2 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 Death effector domain HLH PF00010.26 OWF54968.1 - 5.3e-09 35.9 0.1 1.2e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nup160 PF11715.8 OWF54969.1 - 9.3e-74 249.0 0.2 1.3e-73 248.5 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MGC-24 PF05283.11 OWF54971.1 - 0.03 14.8 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Chordopox_L2 PF05803.12 OWF54971.1 - 0.17 11.7 2.1 0.28 11.1 2.1 1.4 1 1 0 1 1 1 0 Chordopoxvirus L2 protein Sina PF03145.16 OWF54972.1 - 7.7e-85 283.9 0.5 7.7e-85 283.9 0.5 1.4 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 OWF54972.1 - 0.56 10.1 16.3 0.23 11.3 12.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C101 PF16218.5 OWF54973.1 - 4.7e-59 199.8 0.0 7.3e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C101 Tetraspanin PF00335.20 OWF54974.1 - 3e-52 177.6 20.7 3.5e-52 177.4 20.7 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 OWF54974.1 - 0.039 13.7 0.1 0.039 13.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DUF1218 PF06749.12 OWF54974.1 - 0.19 12.3 19.0 0.3 11.6 6.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF872 PF05915.12 OWF54974.1 - 3.1 8.0 9.4 1 9.5 4.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) FKBP_C PF00254.28 OWF54975.1 - 1.9e-52 175.5 0.1 6.9e-29 100.0 0.0 2.6 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 OWF54975.1 - 5.9e-17 60.7 5.2 8.6e-08 31.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF54975.1 - 9.1e-15 53.5 4.2 1.1e-06 28.2 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF54975.1 - 4.6e-13 48.2 3.6 1.7e-06 27.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 OWF54975.1 - 3.2e-08 33.7 1.9 0.0034 17.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OWF54975.1 - 1.9e-07 31.3 1.3 3.6e-05 24.0 0.5 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF54975.1 - 4.7e-07 29.7 3.3 6.5e-05 23.0 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF54975.1 - 1.7e-06 28.4 2.9 0.072 13.6 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat FKBP_N_2 PF18023.1 OWF54975.1 - 6.7e-05 23.0 0.0 0.082 13.0 0.0 3.2 2 1 0 2 2 2 1 BDBT FKBP like N-terminal TPR_11 PF13414.6 OWF54975.1 - 0.00019 21.0 0.1 0.19 11.5 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 OWF54975.1 - 0.00033 21.2 0.4 0.18 12.7 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF54975.1 - 0.00068 19.5 0.5 3.4 7.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF54975.1 - 0.0011 19.1 6.6 0.045 14.0 0.2 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OWF54975.1 - 0.0017 18.9 0.4 0.0091 16.6 0.1 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF54975.1 - 0.0029 17.7 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OWF54975.1 - 0.01 16.3 3.6 0.16 12.4 0.8 2.6 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation PknG_TPR PF16918.5 OWF54975.1 - 0.046 12.5 0.2 0.068 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 OWF54975.1 - 0.62 10.2 3.2 7.3 6.7 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Tfb4 PF03850.14 OWF54975.1 - 0.72 9.3 2.9 1.5 8.3 2.9 1.5 1 1 0 1 1 1 0 Transcription factor Tfb4 MIF4G_like_2 PF09090.11 OWF54975.1 - 4.5 6.7 9.0 0.54 9.7 4.1 1.7 2 0 0 2 2 2 0 MIF4G like SH3_1 PF00018.28 OWF54976.1 - 5.6e-53 176.3 6.8 1.7e-10 40.4 0.0 6.6 6 0 0 6 6 6 6 SH3 domain SH3_9 PF14604.6 OWF54976.1 - 5e-49 163.9 5.0 5.4e-14 51.8 0.1 7.8 8 0 0 8 8 8 6 Variant SH3 domain SH3_2 PF07653.17 OWF54976.1 - 6.1e-42 141.1 2.4 4.6e-07 29.4 0.0 7.5 7 0 0 7 7 7 6 Variant SH3 domain RhoGEF PF00621.20 OWF54976.1 - 1.5e-36 126.3 1.6 1.5e-36 126.3 1.6 2.5 3 0 0 3 3 3 1 RhoGEF domain BAR PF03114.18 OWF54976.1 - 5.5e-24 85.1 1.8 5.5e-24 85.1 1.8 2.8 2 1 1 3 3 1 1 BAR domain hSH3 PF14603.6 OWF54976.1 - 0.012 16.1 0.8 3.3 8.2 0.0 3.4 3 0 0 3 3 3 0 Helically-extended SH3 domain YlqD PF11068.8 OWF54976.1 - 0.67 10.3 19.3 0.25 11.7 15.5 2.3 2 0 0 2 2 2 0 YlqD protein U1snRNP70_N PF12220.8 OWF54976.1 - 0.72 10.5 11.4 20 5.9 8.4 3.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pinin_SDK_memA PF04696.13 OWF54976.1 - 0.72 9.9 16.8 3.1 7.8 16.8 2.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF3993 PF13158.6 OWF54976.1 - 1.9 8.7 7.5 43 4.4 2.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3993) HSP70 PF00012.20 OWF54976.1 - 4.6 5.3 11.2 7.9 4.5 11.2 1.3 1 0 0 1 1 1 0 Hsp70 protein FKBP_N PF01346.18 OWF54976.1 - 5.2 8.1 8.9 20 6.3 8.9 2.0 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase V_ATPase_I PF01496.19 OWF54976.1 - 9.8 3.9 11.1 21 2.9 11.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ROS_MUCR PF05443.11 OWF54977.1 - 0.089 12.8 0.1 0.089 12.8 0.1 2.3 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein zf-C2H2_4 PF13894.6 OWF54978.1 - 3.7e-10 39.8 42.2 0.046 14.6 4.7 7.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF54978.1 - 7e-06 26.2 41.2 0.011 16.2 1.6 6.0 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OWF54978.1 - 0.0048 16.9 31.7 0.042 13.9 0.2 5.5 6 0 0 6 6 6 4 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 OWF54978.1 - 0.031 15.0 2.1 0.031 15.0 2.1 5.5 3 1 2 5 5 5 0 zinc-ribbon family zf-H2C2_2 PF13465.6 OWF54979.1 - 1.8e-38 129.2 61.1 7.1e-07 29.4 1.9 8.6 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 OWF54979.1 - 1.1e-32 110.6 80.6 5.2e-07 29.8 1.2 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF54979.1 - 5.3e-28 95.3 69.4 2.5e-05 24.7 0.8 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 OWF54979.1 - 6.9e-17 61.2 54.3 0.0018 18.6 1.0 8.9 8 1 0 8 8 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF54979.1 - 3.5e-11 43.1 56.4 0.17 12.2 0.4 9.0 8 1 0 8 8 8 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 OWF54979.1 - 2.8e-05 24.3 13.4 1.6 9.0 0.0 5.6 3 1 3 6 6 6 3 BolA-like protein zf-Di19 PF05605.12 OWF54979.1 - 5.1e-05 23.5 41.5 0.26 11.6 8.6 5.5 3 2 2 5 5 5 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OWF54979.1 - 0.0018 18.2 0.5 0.0018 18.2 0.5 9.4 10 1 0 10 10 9 5 C2H2-type zinc finger Baculo_IE-1 PF05290.11 OWF54979.1 - 0.043 13.8 25.2 0.7 9.8 1.7 6.3 2 2 3 5 5 5 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_2 PF12756.7 OWF54979.1 - 0.084 13.2 53.4 0.049 14.0 10.8 6.8 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OWF54979.1 - 0.14 12.0 0.2 0.14 12.0 0.2 7.5 7 0 0 7 7 7 0 zinc-finger C2H2-type GAGA PF09237.11 OWF54979.1 - 0.16 11.8 0.1 0.16 11.8 0.1 6.0 4 2 2 7 7 7 0 GAGA factor zf-C2H2_8 PF15909.5 OWF54979.1 - 1.4 9.2 35.9 1.9 8.9 7.8 4.1 1 1 3 4 4 4 0 C2H2-type zinc ribbon DUF2892 PF11127.8 OWF54982.1 - 0.1 12.6 0.6 0.22 11.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) CD225 PF04505.12 OWF54983.1 - 1.6e-06 28.2 0.2 2.7e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein C2 PF00168.30 OWF54984.1 - 1.8e-21 76.3 0.0 4.1e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 OWF54984.1 - 0.0092 16.6 1.4 0.28 11.9 0.0 3.2 3 0 0 3 3 3 1 Putative heavy-metal-binding RHINO PF15319.6 OWF54985.1 - 2.1e-16 60.7 11.9 3.6e-15 56.7 11.9 2.1 1 1 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein Forkhead PF00250.18 OWF54986.1 - 3.1e-27 94.7 0.5 7.2e-27 93.5 0.5 1.7 1 0 0 1 1 1 1 Forkhead domain UreD PF01774.17 OWF54987.1 - 6.8e-50 169.9 0.0 1.1e-49 169.3 0.0 1.3 1 0 0 1 1 1 1 UreD urease accessory protein PLAT PF01477.23 OWF54988.1 - 0 1113.5 76.5 2.8e-24 85.9 0.1 17.7 18 0 0 18 18 18 17 PLAT/LH2 domain ATS3 PF06232.11 OWF54988.1 - 1.4e-25 89.6 2.4 0.075 12.9 0.0 13.2 15 0 0 15 15 15 7 Embryo-specific protein 3, (ATS3) Lactamase_B_5 PF14597.6 OWF54988.1 - 0.0065 16.0 0.9 14 5.1 0.0 5.3 6 0 0 6 6 6 1 Metallo-beta-lactamase superfamily PAS_10 PF13596.6 OWF54988.1 - 0.29 11.7 2.3 1.4e+02 3.1 0.0 4.4 4 0 0 4 4 4 0 PAS domain Coa1 PF08695.10 OWF54988.1 - 0.34 10.7 2.0 5.5 6.8 0.0 3.5 3 0 0 3 3 3 0 Cytochrome oxidase complex assembly protein 1 DUF4239 PF14023.6 OWF54989.1 - 2.3e-05 24.2 1.5 2.3e-05 24.2 1.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4239) Ribosomal_S17_N PF16205.5 OWF54990.1 - 6.9e-31 106.4 0.3 6.9e-31 106.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OWF54990.1 - 3.6e-26 91.1 2.5 5.2e-26 90.5 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.11 OWF54990.1 - 0.1 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF DUF5487 PF17589.2 OWF54990.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5487) PAS_11 PF14598.6 OWF54991.1 - 2.6e-26 92.0 0.2 2e-22 79.4 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 OWF54991.1 - 1.6e-20 73.2 0.1 1.3e-13 51.0 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OWF54991.1 - 9.3e-19 67.5 0.1 6.7e-10 39.0 0.0 2.9 3 0 0 3 3 3 2 PAS fold HLH PF00010.26 OWF54991.1 - 1.7e-15 56.7 2.1 4.6e-15 55.3 2.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 OWF54991.1 - 8e-08 32.5 0.0 0.00059 20.1 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OWF54991.1 - 8.9e-05 22.7 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 OWF54991.1 - 0.01 16.5 0.0 0.043 14.5 0.0 2.0 2 0 0 2 2 2 0 PAS fold TSP_3 PF02412.18 OWF54992.1 - 0.092 12.4 2.6 0.21 11.3 2.6 1.6 1 0 0 1 1 1 0 Thrombospondin type 3 repeat DUF4663 PF15668.5 OWF54993.1 - 6.8e-26 91.1 0.0 7.8e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4663) CAP_C PF08603.11 OWF54993.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DUF4663 PF15668.5 OWF54994.1 - 7.8e-15 54.8 0.0 9.9e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4663) Ion_trans PF00520.31 OWF54995.1 - 2.5e-33 115.3 11.4 4.1e-33 114.6 11.4 1.3 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 OWF54995.1 - 1.7e-27 95.4 0.2 4.2e-27 94.1 0.2 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 OWF54995.1 - 9.3e-12 44.3 3.7 1.5e-11 43.6 3.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 OWF54995.1 - 2.4e-10 40.9 0.0 2.9e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF54995.1 - 8.9e-09 34.9 0.3 1.5 9.6 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OWF54995.1 - 9.3e-05 22.9 0.2 0.46 11.1 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF54995.1 - 0.013 15.9 0.3 4.4 7.9 0.1 3.7 3 1 1 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 OWF54995.1 - 0.016 15.5 0.1 6 7.3 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) zf-C2H2 PF00096.26 OWF54996.1 - 1.9e-32 109.9 55.8 0.00013 22.2 1.7 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF54996.1 - 2.9e-23 80.5 53.9 0.00026 21.6 1.7 9.7 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF54996.1 - 1.3e-17 63.4 58.2 0.00021 21.6 0.3 10.2 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_8 PF15909.5 OWF54996.1 - 0.0001 22.5 23.4 0.35 11.2 1.7 5.6 1 1 4 5 5 5 4 C2H2-type zinc ribbon FOXP-CC PF16159.5 OWF54996.1 - 0.00011 22.8 29.0 0.25 12.0 0.3 7.8 2 2 6 8 8 8 3 FOXP coiled-coil domain zf_Hakai PF18408.1 OWF54996.1 - 0.00014 21.5 0.3 0.00014 21.5 0.3 6.9 8 0 0 8 8 8 1 C2H2 Hakai zinc finger domain zf-Di19 PF05605.12 OWF54996.1 - 0.0019 18.5 24.5 0.012 15.9 0.4 5.8 2 2 4 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 OWF54996.1 - 0.0099 16.0 28.5 0.88 9.7 0.4 6.8 1 1 3 6 6 6 3 Aberrant zinc-finger zf-TRAF PF02176.18 OWF54996.1 - 0.016 15.9 14.3 0.025 15.2 3.4 6.2 4 1 3 8 8 7 0 TRAF-type zinc finger zf-C2H2_6 PF13912.6 OWF54996.1 - 0.059 13.4 0.7 0.059 13.4 0.7 6.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF54996.1 - 0.095 13.0 28.6 0.17 12.2 0.1 7.2 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 OWF54996.1 - 0.85 9.6 12.2 31 4.6 0.0 5.8 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 OWF54996.1 - 0.94 9.3 22.1 3.2 7.6 0.5 6.0 7 0 0 7 7 6 0 zinc-finger C2H2-type zf-met PF12874.7 OWF54996.1 - 1.4 9.4 17.5 28 5.3 0.3 6.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 OWF54996.1 - 1.6 9.2 8.0 0.96 10.0 0.3 4.0 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HC_2 PF13913.6 OWF54996.1 - 5.4 7.0 29.8 1.7 8.7 0.5 8.0 8 0 0 8 8 8 0 zinc-finger of a C2HC-type CitMHS PF03600.16 OWF54997.1 - 3e-36 125.2 6.5 3e-36 125.2 6.5 1.5 2 0 0 2 2 2 1 Citrate transporter ArsB PF02040.15 OWF54997.1 - 2.7e-05 23.7 11.8 4.5e-05 23.0 11.8 1.3 1 0 0 1 1 1 1 Arsenical pump membrane protein DUF2207 PF09972.9 OWF54997.1 - 0.016 14.0 11.1 0.1 11.3 0.3 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) zf-U1 PF06220.12 OWF54998.1 - 1.8e-14 53.2 1.5 3.2e-14 52.4 1.5 1.4 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 OWF54998.1 - 7.3e-06 26.0 2.4 1.4e-05 25.0 2.4 1.5 1 0 0 1 1 1 1 WW domain UCR_TM PF02921.14 OWF54998.1 - 0.18 12.3 1.3 0.49 10.9 0.6 2.1 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Glutaredoxin2_C PF04399.13 OWF54998.1 - 0.47 10.3 3.2 0.9 9.4 3.2 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ALMT PF11744.8 OWF54998.1 - 1.9 7.2 10.5 2.4 6.9 10.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 OWF54998.1 - 10 4.8 10.3 14 4.3 10.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MBT PF02820.18 OWF54999.1 - 2.5e-91 300.1 4.8 8.1e-25 87.0 0.0 4.3 4 0 0 4 4 4 4 mbt repeat SAM_1 PF00536.30 OWF54999.1 - 4.4e-10 39.8 0.1 8.7e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF54999.1 - 7.6e-06 25.8 0.1 2.3e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 OWF54999.1 - 0.0065 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 OWF54999.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Rad60-SLD PF11976.8 OWF55000.1 - 4.3e-22 77.7 0.0 5.8e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OWF55000.1 - 1.3e-08 34.4 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family CUB PF00431.20 OWF55001.1 - 4.5e-19 68.8 0.1 1.8e-05 25.0 0.0 6.4 7 0 0 7 7 7 5 CUB domain Ldl_recept_a PF00057.18 OWF55001.1 - 5.6e-09 36.1 8.4 1.1e-08 35.2 8.4 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A 7tm_1 PF00001.21 OWF55002.1 - 2e-21 76.5 20.0 2.7e-21 76.1 20.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 OWF55002.1 - 1.6e-14 53.9 18.6 2.5e-14 53.3 18.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF55002.1 - 0.00011 21.9 16.9 0.00021 21.0 16.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx zinc-ribbons_6 PF07191.12 OWF55003.1 - 0.001 19.0 24.8 0.49 10.4 4.7 3.2 1 1 3 4 4 4 4 zinc-ribbons DUF326 PF03860.16 OWF55003.1 - 0.0025 17.7 24.1 52 4.0 0.1 7.8 8 0 0 8 8 8 0 Domain of Unknown Function (DUF326) Fer4_3 PF12798.7 OWF55003.1 - 1.8 9.7 30.6 1.3e+02 3.8 0.2 7.9 8 0 0 8 8 8 0 4Fe-4S binding domain DUF35_N PF12172.8 OWF55003.1 - 3.4 7.6 21.3 1.4e+02 2.5 0.0 7.3 7 1 0 7 7 7 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ubiquitin PF00240.23 OWF55004.1 - 0.00017 21.2 0.5 0.00065 19.4 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family HMG_box PF00505.19 OWF55005.1 - 1.6e-10 41.2 1.0 3.6e-10 40.1 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF55005.1 - 0.0022 18.6 2.2 0.0022 18.6 2.2 2.4 2 0 0 2 2 2 1 HMG-box domain RPA_C PF08784.11 OWF55005.1 - 0.056 14.1 0.5 0.67 10.6 0.0 2.8 2 0 0 2 2 2 0 Replication protein A C terminal Y_phosphatase PF00102.27 OWF55006.1 - 6.4e-108 359.7 3.7 1.2e-61 208.3 0.2 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OWF55006.1 - 0.11 12.2 0.2 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DOMON PF03351.17 OWF55007.1 - 9.5e-98 323.1 30.3 1e-23 83.9 0.0 6.5 6 0 0 6 6 6 6 DOMON domain SEA PF01390.20 OWF55007.1 - 2.8e-08 33.8 0.2 6.6e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 SEA domain EGF_2 PF07974.13 OWF55007.1 - 0.0016 18.8 9.6 0.0016 18.8 9.6 3.3 3 0 0 3 3 2 2 EGF-like domain LRR_adjacent PF08191.11 OWF55007.1 - 0.0027 17.9 3.3 1.8 8.8 0.0 4.0 3 0 0 3 3 3 1 LRR adjacent CDH-cyt PF16010.5 OWF55007.1 - 0.0063 16.2 15.3 0.039 13.6 0.3 4.2 4 0 0 4 4 4 2 Cytochrome domain of cellobiose dehydrogenase Trypan_PARP PF05887.11 OWF55007.1 - 0.0081 16.1 22.4 0.0081 16.1 22.4 6.1 5 1 1 6 6 6 4 Procyclic acidic repetitive protein (PARP) YokU PF14122.6 OWF55007.1 - 0.017 15.1 3.7 5.8 7.0 0.1 3.5 3 0 0 3 3 3 0 YokU-like protein, putative antitoxin EphA2_TM PF14575.6 OWF55007.1 - 0.08 13.8 0.1 0.58 11.1 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PHAT PF09246.10 OWF55007.1 - 0.15 11.9 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 PHAT LapA_dom PF06305.11 OWF55007.1 - 0.17 11.7 0.0 0.5 10.2 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EGF PF00008.27 OWF55007.1 - 0.21 11.9 16.7 1.3 9.4 6.7 2.9 2 0 0 2 2 2 0 EGF-like domain p450 PF00067.22 OWF55008.1 - 1.4e-103 347.1 0.5 1.6e-103 346.9 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Orai-1 PF07856.12 OWF55009.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity Adeno_E3_CR2 PF02439.15 OWF55009.1 - 8.8 6.2 11.0 25 4.7 11.0 1.7 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 PUL PF08324.11 OWF55010.1 - 3.4e-57 193.8 1.8 4.6e-57 193.4 1.8 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OWF55010.1 - 3.1e-44 149.8 0.8 5.6e-44 149.0 0.8 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OWF55010.1 - 3.7e-41 138.3 13.1 2.8e-07 31.1 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 OWF55010.1 - 0.0039 17.2 0.0 7.5 6.6 0.0 3.4 2 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF2150 PF09920.9 OWF55010.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) IMP2_C PF18591.1 OWF55012.1 - 9.9e-08 31.7 0.3 15 5.6 0.0 7.2 3 3 6 9 9 9 2 Immune Mapped Protein 2 (IMP2) C-terminal domain LRR_8 PF13855.6 OWF55012.1 - 5.4e-05 22.9 14.0 0.095 12.5 0.7 4.6 1 1 2 4 4 4 4 Leucine rich repeat TrmE_N PF10396.9 OWF55012.1 - 0.00018 21.8 16.2 39 4.6 2.1 7.8 1 1 2 3 3 3 0 GTP-binding protein TrmE N-terminus DUF4057 PF13266.6 OWF55012.1 - 0.00026 20.8 1.6 0.00071 19.4 1.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4057) PIRT PF15099.6 OWF55012.1 - 0.19 11.3 11.5 6.3 6.4 0.1 4.1 1 1 2 4 4 4 0 Phosphoinositide-interacting protein family IMP2_C PF18591.1 OWF55013.1 - 1.2e-12 47.5 6.4 49 3.9 0.0 15.2 6 5 12 19 19 19 0 Immune Mapped Protein 2 (IMP2) C-terminal domain LRR_8 PF13855.6 OWF55013.1 - 2.2e-08 33.7 43.8 0.26 11.1 0.4 11.6 5 2 11 17 17 17 7 Leucine rich repeat TrmE_N PF10396.9 OWF55013.1 - 7.8e-06 26.2 63.9 50 4.3 0.5 19.7 1 1 9 10 10 10 0 GTP-binding protein TrmE N-terminus zf-CCHC_3 PF13917.6 OWF55013.1 - 0.66 10.0 4.8 70 3.5 0.0 6.2 6 0 0 6 6 6 0 Zinc knuckle PilW PF16074.5 OWF55013.1 - 6 6.9 6.5 23 5.0 0.0 4.6 5 1 1 6 6 6 0 Type IV Pilus-assembly protein W Paramyxo_NS_C PF02725.14 OWF55013.1 - 7.6 6.6 25.2 38 4.3 0.0 7.9 3 2 4 8 8 8 0 Non-structural protein C IMP2_C PF18591.1 OWF55014.1 - 2.4e-07 30.5 0.4 2.6 8.0 0.0 6.4 1 1 7 8 8 8 3 Immune Mapped Protein 2 (IMP2) C-terminal domain TrmE_N PF10396.9 OWF55014.1 - 0.0002 21.7 16.8 11 6.3 0.8 7.4 1 1 4 5 5 5 2 GTP-binding protein TrmE N-terminus LRR_8 PF13855.6 OWF55014.1 - 0.0065 16.2 13.1 1 9.2 0.5 4.1 1 1 5 6 6 6 5 Leucine rich repeat DUF3954 PF13128.6 OWF55014.1 - 0.21 11.4 7.8 79 3.2 0.0 5.5 4 2 2 6 6 6 0 Protein of unknown function (DUF3954) DUF229 PF02995.17 OWF55015.1 - 5.2e-109 365.1 5.7 6.9e-109 364.7 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF55015.1 - 3.4e-05 23.4 0.1 0.00045 19.7 0.0 2.2 1 1 1 2 2 2 1 Sulfatase DUF1501 PF07394.12 OWF55015.1 - 0.071 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Ribosomal_L31 PF01197.18 OWF55016.1 - 3.9e-08 33.4 74.8 1.8e+04 -61.7 74.4 17.3 1 1 0 1 1 1 0 Ribosomal protein L31 Paramyxo_PNT PF14320.6 OWF55016.1 - 0.0059 15.8 33.0 4.4 6.4 1.2 5.9 1 1 3 5 5 5 5 Phosphoprotein P region PNT disordered Ion_trans PF00520.31 OWF55017.1 - 1.3e-25 90.1 16.4 1.7e-25 89.7 16.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF55017.1 - 4.9e-07 29.6 1.3 1.9e-06 27.8 1.3 2.0 1 0 0 1 1 1 1 Ion channel Bac_rhamnosid_C PF17390.2 OWF55018.1 - 1.2e-43 146.7 73.9 2.3 8.1 0.1 28.6 1 1 45 46 46 46 46 Bacterial alpha-L-rhamnosidase C-terminal domain DUF4268 PF14088.6 OWF55018.1 - 1e-38 132.3 8.6 15 5.5 0.0 26.2 1 1 32 33 33 33 15 Domain of unknown function (DUF4268) DUF4794 PF16042.5 OWF55018.1 - 0.00011 23.1 0.0 82 4.3 0.0 11.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4794) NUC173 PF08161.12 OWF55020.1 - 0.086 12.5 0.1 7.5 6.1 0.0 2.3 2 1 0 2 2 2 0 NUC173 domain OCRE PF17780.1 OWF55020.1 - 3.2 7.9 24.1 5.4 7.1 1.5 3.2 3 0 0 3 3 3 0 OCRE domain cNMP_binding PF00027.29 OWF55021.1 - 2.8e-21 75.4 0.0 4.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain BBP1_C PF15272.6 OWF55022.1 - 0.079 12.8 0.5 0.12 12.1 0.5 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Lyase_1 PF00206.20 OWF55023.1 - 7.1e-19 68.3 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OWF55023.1 - 2.2e-11 44.1 0.0 4.8e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Tnp_22_trimer PF17489.2 OWF55023.1 - 0.034 14.1 0.9 0.081 12.9 0.9 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain EIAV_Rev PF11129.8 OWF55023.1 - 0.041 14.1 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus DUF1331 PF07048.11 OWF55023.1 - 0.067 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Methyltransf_31 PF13847.6 OWF55023.1 - 0.071 12.9 0.0 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Integrin_alpha2 PF08441.12 OWF55024.1 - 1.2e-85 288.2 0.1 1.4e-85 287.9 0.1 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 OWF55024.1 - 9.5e-18 64.0 29.0 2.8e-08 33.7 2.3 5.6 7 0 0 7 7 7 3 FG-GAP repeat VCBS PF13517.6 OWF55024.1 - 4.5e-09 36.8 11.8 0.0022 18.6 0.2 5.3 4 2 2 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 OWF55024.1 - 4.4e-08 33.2 14.8 0.037 14.3 2.1 5.5 5 0 0 5 5 5 3 FG-GAP repeat LYRIC PF15686.5 OWF55024.1 - 0.0023 17.6 0.2 0.004 16.8 0.2 1.3 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Integrin_alpha PF00357.20 OWF55024.1 - 0.012 15.5 1.3 0.038 14.0 1.3 1.9 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region TMEM192 PF14802.6 OWF55024.1 - 0.11 11.6 0.0 0.85 8.7 0.0 2.1 2 0 0 2 2 2 0 TMEM192 family DUF4381 PF14316.6 OWF55024.1 - 0.21 11.9 0.4 0.4 10.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Flagellin_N PF00669.20 OWF55025.1 - 0.024 14.7 2.9 4.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4618 PF15397.6 OWF55025.1 - 0.037 13.5 2.8 0.21 11.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.12 OWF55025.1 - 0.037 14.1 4.4 0.15 12.1 3.4 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CHDCT2 PF08074.11 OWF55025.1 - 0.07 13.3 2.8 4.2 7.5 0.1 2.4 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain ApoLp-III PF07464.11 OWF55025.1 - 0.15 12.1 3.1 0.4 10.8 3.1 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 OWF55025.1 - 0.87 9.4 3.8 1.3 8.8 0.7 2.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 OWF55025.1 - 2.1 8.4 5.3 13 5.9 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) dNK PF01712.19 OWF55026.1 - 1.4e-22 80.6 0.2 2.1e-22 80.0 0.2 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 OWF55026.1 - 0.00044 20.0 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 Thymidylate kinase UQ_con PF00179.26 OWF55027.1 - 2.4e-14 53.1 0.0 5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme INSIG PF07281.12 OWF55027.1 - 0.21 11.2 0.0 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) 7tm_2 PF00002.24 OWF55028.1 - 3.8e-62 209.8 22.5 5.3e-62 209.3 22.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 OWF55028.1 - 9.5e-12 45.0 1.6 2.3e-11 43.8 1.6 1.7 1 0 0 1 1 1 1 Hormone receptor domain BDV_P10 PF06515.11 OWF55028.1 - 0.14 12.2 0.2 14 5.8 0.0 2.8 3 0 0 3 3 3 0 Borna disease virus P10 protein DUF1980 PF09323.10 OWF55028.1 - 1.4 8.8 8.3 6 6.7 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) OAM_dimer PF16554.5 OWF55029.1 - 0.038 14.4 8.3 26 5.4 0.3 4.5 1 1 4 5 5 5 0 Dimerisation domain of d-ornithine 4,5-aminomutase ETM PF17577.2 OWF55029.1 - 0.22 12.1 1.0 30 5.2 0.1 2.9 1 1 2 3 3 3 0 ECORI-T site Grp7_allergen PF16984.5 OWF55029.1 - 0.32 11.0 4.8 2.7 8.0 0.7 2.0 1 1 1 2 2 2 0 Group 7 allergen sCache_3_2 PF17203.4 OWF55029.1 - 0.65 10.1 10.4 41 4.3 0.1 4.4 1 1 4 5 5 5 0 Single cache domain 3 Ribosomal_L7Ae PF01248.26 OWF55030.1 - 0.041 13.6 3.2 60 3.5 0.1 5.4 1 1 7 10 10 10 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rib PF08428.10 OWF55030.1 - 0.33 11.0 8.6 2.3 8.3 1.6 2.9 1 1 2 3 3 3 0 Rib/alpha-like repeat DUF3953 PF13129.6 OWF55030.1 - 1 9.2 17.9 2.9 7.7 1.0 5.5 4 1 2 7 7 7 0 Protein of unknown function (DUF3953) Pyrid_ox_like PF16242.5 OWF55030.1 - 6.9 6.3 11.2 9.4 5.8 1.1 3.4 2 2 2 4 4 4 0 Pyridoxamine 5'-phosphate oxidase like DUF3953 PF13129.6 OWF55031.1 - 1.2 8.9 8.3 3.7 7.4 0.2 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF3953) Dehydratase_MU PF02288.15 OWF55032.1 - 0.1 12.5 11.6 18 5.3 4.7 4.0 1 1 2 3 3 3 0 Dehydratase medium subunit Ribosomal_L7Ae PF01248.26 OWF55032.1 - 0.11 12.2 0.2 21 4.9 0.0 3.5 1 1 4 5 5 5 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SNF5 PF04855.12 OWF55032.1 - 0.13 12.1 2.7 0.15 11.8 2.7 1.0 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 NT5C PF06941.12 OWF55033.1 - 1.9e-12 47.5 0.2 2.2e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) XPG_I PF00867.18 OWF55034.1 - 0.0033 17.7 8.4 27 5.2 0.6 5.7 1 1 2 3 3 3 3 XPG I-region PLDc_2 PF13091.6 OWF55034.1 - 1.5 8.7 20.6 1.8e+04 -9.8 20.6 4.4 1 1 0 1 1 1 0 PLD-like domain DUF3828 PF12883.7 OWF55034.1 - 2 8.8 10.4 23 5.4 1.3 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3828) ComX PF05952.12 OWF55034.1 - 4.8 7.2 7.2 13 5.8 0.0 4.7 5 2 0 5 5 5 0 Bacillus competence pheromone ComX 2OG-FeII_Oxy_3 PF13640.6 OWF55035.1 - 7.7e-15 55.6 0.1 1.5e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OWF55035.1 - 1.2e-07 32.1 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 OWF55035.1 - 0.043 13.9 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Transglut_core PF01841.19 OWF55037.1 - 1.4e-18 67.4 0.0 3.8e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase-like superfamily Y_Y_Y PF07495.13 OWF55037.1 - 0.0017 18.2 0.0 1.5 8.9 0.0 3.5 3 0 0 3 3 3 2 Y_Y_Y domain SNF PF00209.18 OWF55038.1 - 1.6e-16 60.1 41.1 6.5e-08 31.7 8.8 3.1 2 1 1 3 3 3 3 Sodium:neurotransmitter symporter family GST_N_4 PF17172.4 OWF55039.1 - 9.2e-27 93.7 0.0 1.8e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OWF55039.1 - 1.1e-18 66.7 0.0 1.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF55039.1 - 3.6e-06 26.9 0.0 6.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OWF55039.1 - 4.8e-06 26.9 0.0 1.5e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 OWF55039.1 - 0.1 12.8 0.0 0.81 9.9 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DOCK_N PF16172.5 OWF55042.1 - 4.3e-96 322.1 0.3 1.6e-95 320.3 0.1 2.1 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 OWF55042.1 - 1.6e-87 294.3 4.7 1.6e-87 294.3 4.7 2.6 2 1 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 OWF55042.1 - 8.2e-53 179.1 1.2 5.7e-51 173.1 0.9 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.17 OWF55042.1 - 0.0001 21.9 0.1 0.00025 20.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OWF55042.1 - 0.00026 20.8 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF55042.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_16 PF18348.1 OWF55042.1 - 0.21 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain FAP206 PF12018.8 OWF55043.1 - 2.3e-100 335.6 3.1 4.4e-100 334.7 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function YHS PF04945.13 OWF55043.1 - 0.013 15.5 0.2 0.032 14.3 0.2 1.5 1 0 0 1 1 1 0 YHS domain GCP_N_terminal PF17681.1 OWF55043.1 - 0.02 14.6 1.1 0.051 13.2 0.6 1.8 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal DUF4238 PF14022.6 OWF55043.1 - 0.16 11.5 0.9 0.58 9.6 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4238) End3 PF12761.7 OWF55043.1 - 0.19 11.9 3.5 0.59 10.3 0.7 2.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 BID PF06393.11 OWF55043.1 - 0.24 10.9 4.0 0.27 10.8 0.4 2.7 3 1 1 4 4 4 0 BH3 interacting domain (BID) APG6_N PF17675.1 OWF55043.1 - 2 8.9 8.5 0.095 13.2 1.4 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Mtc PF03820.17 OWF55044.1 - 2.7e-130 434.0 2.2 3.1e-130 433.8 2.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier UCR_TM PF02921.14 OWF55044.1 - 0.097 13.2 0.1 0.27 11.8 0.0 1.7 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region C1q PF00386.21 OWF55045.1 - 5.4e-21 75.1 1.0 8.5e-21 74.5 1.0 1.3 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 OWF55045.1 - 1.1e-09 37.9 18.9 1.1e-09 37.9 18.9 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) GAS PF13851.6 OWF55045.1 - 0.0018 17.6 2.0 0.0028 17.0 2.0 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding EzrA PF06160.12 OWF55045.1 - 0.002 16.4 0.6 0.0028 15.9 0.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 OWF55045.1 - 0.0044 16.0 0.4 0.0076 15.2 0.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein HOOK PF05622.12 OWF55045.1 - 0.026 12.7 2.7 0.035 12.3 2.7 1.1 1 0 0 1 1 1 0 HOOK protein AHD PF17793.1 OWF55045.1 - 0.044 13.6 1.1 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Jnk-SapK_ap_N PF09744.9 OWF55045.1 - 0.12 12.6 5.5 0.2 11.9 5.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 BclA_C PF18573.1 OWF55045.1 - 0.29 11.1 7.1 0.042 13.8 2.0 2.0 2 0 0 2 2 2 0 BclA C-terminal domain Mtc PF03820.17 OWF55046.1 - 2.8e-142 473.4 0.2 3.1e-142 473.2 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier UCR_TM PF02921.14 OWF55046.1 - 0.025 15.1 0.0 0.071 13.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region DNA_pol_A PF00476.20 OWF55047.1 - 6.3e-114 380.9 0.0 1.1e-113 380.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 OWF55047.1 - 8.9e-12 44.9 0.8 2.3e-11 43.5 0.8 1.7 1 0 0 1 1 1 1 DNA polymerase nu pseudo-exo Tmpp129 PF10272.9 OWF55048.1 - 7.5e-136 453.1 2.7 8.5e-136 452.9 2.7 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-RING_2 PF13639.6 OWF55048.1 - 0.24 11.8 13.2 1.7 9.0 13.2 2.3 1 1 0 1 1 1 0 Ring finger domain SET PF00856.28 OWF55049.1 - 8.1e-15 55.6 0.6 2e-14 54.3 0.6 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OWF55049.1 - 0.00077 19.5 14.2 0.00077 19.5 14.2 3.1 3 0 0 3 3 3 1 MYND finger Nop14 PF04147.12 OWF55050.1 - 1.2e-246 821.2 62.4 1.4e-246 821.0 62.4 1.0 1 0 0 1 1 1 1 Nop14-like family NPH3 PF03000.14 OWF55051.1 - 8.2e-16 58.4 0.0 7.7e-14 52.0 0.0 2.2 1 1 0 1 1 1 1 NPH3 family BTB PF00651.31 OWF55051.1 - 6.6e-12 45.6 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 OWF55051.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Mito_carr PF00153.27 OWF55052.1 - 2e-65 216.8 1.7 9.3e-21 73.6 0.2 3.1 1 1 2 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 OWF55053.1 - 1.1e-40 138.9 0.1 1.5e-40 138.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF55053.1 - 1.3e-26 93.2 0.1 2.2e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF55053.1 - 3.2e-11 43.0 0.0 4.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF55053.1 - 6.5e-05 22.4 0.2 9.5e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OWF55053.1 - 0.015 15.0 0.5 0.055 13.2 0.0 2.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OWF55053.1 - 0.045 12.9 0.3 0.64 9.1 0.1 2.5 1 1 2 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 OWF55053.1 - 0.051 13.3 0.6 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-nanos PF05741.13 OWF55054.1 - 6.2e-23 80.8 5.7 1.5e-22 79.5 5.7 1.7 1 0 0 1 1 1 1 Nanos RNA binding domain zf-HIT PF04438.16 OWF55054.1 - 0.037 13.9 3.7 0.11 12.4 0.8 2.8 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_2 PF12756.7 OWF55054.1 - 0.071 13.5 2.9 0.066 13.5 1.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RVT PF13966.6 OWF55054.1 - 0.088 13.5 2.9 2.7 8.7 0.3 2.5 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase DZR PF12773.7 OWF55054.1 - 0.25 11.4 3.0 0.68 10.0 3.0 1.8 1 0 0 1 1 1 0 Double zinc ribbon DUF842 PF05811.13 OWF55055.1 - 1.6e-36 124.9 14.1 1.8e-36 124.8 14.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-Tim10_DDP PF02953.15 OWF55055.1 - 0.012 15.2 14.4 0.021 14.5 5.5 2.8 1 1 1 2 2 2 0 Tim10/DDP family zinc finger RasGAP_C PF03836.15 OWF55055.1 - 0.013 15.6 1.0 0.028 14.5 0.8 1.8 1 1 0 1 1 1 0 RasGAP C-terminus Phage_TAC_8 PF10666.9 OWF55055.1 - 0.044 14.1 0.8 0.061 13.6 0.8 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 THDPS_N_2 PF14805.6 OWF55055.1 - 0.08 13.2 0.1 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Vicilin_N PF04702.12 OWF55055.1 - 0.37 10.6 13.9 0.28 11.0 12.7 1.4 1 1 0 1 1 1 0 Vicilin N terminal region Vanabin-2 PF11437.8 OWF55055.1 - 0.73 10.0 12.0 2.8 8.2 7.8 2.4 1 1 1 2 2 2 0 Vanadium-binding protein 2 Bcr-Abl_Oligo PF09036.10 OWF55055.1 - 1.9 8.5 8.8 4.6 7.3 0.9 3.4 1 1 3 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain CoA_transf_3 PF02515.17 OWF55056.1 - 1.6e-105 353.3 0.0 1.9e-105 353.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 OWF55056.1 - 0.075 13.0 0.0 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) U-box PF04564.15 OWF55058.1 - 2.7e-17 62.7 0.0 6.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.6 OWF55058.1 - 0.0014 18.4 11.4 0.0037 17.1 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF55058.1 - 0.011 15.6 8.5 0.011 15.6 8.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OWF55058.1 - 0.027 14.4 13.3 0.11 12.5 13.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 OWF55058.1 - 0.077 13.3 12.7 0.89 9.9 13.1 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 OWF55058.1 - 1.4 9.0 10.9 36 4.5 0.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger WD40 PF00400.32 OWF55059.1 - 3.9e-15 56.0 3.1 0.0085 16.9 0.0 6.4 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55059.1 - 0.00023 21.4 0.0 12 6.3 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF55059.1 - 0.065 12.5 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Zip PF02535.22 OWF55060.1 - 7.6e-69 232.5 0.4 1.1e-68 231.9 0.4 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter F-box-like PF12937.7 OWF55061.1 - 6.7e-13 48.3 0.6 1.7e-12 47.0 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF55061.1 - 2.2e-07 30.6 0.3 8.8e-07 28.7 0.3 2.2 1 0 0 1 1 1 1 F-box domain p450 PF00067.22 OWF55062.1 - 5.2e-59 200.2 0.0 6.4e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5318 PF17249.2 OWF55062.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5318) DNA_pol_B_thumb PF14791.6 OWF55063.1 - 2.3e-17 62.9 0.0 4.9e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 OWF55063.1 - 4.9e-11 42.8 0.0 1.7e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 OWF55063.1 - 1.3e-09 37.7 0.0 2.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OWF55063.1 - 8.3e-08 32.5 0.0 3.9e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 OWF55063.1 - 0.013 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain BRCT_2 PF16589.5 OWF55063.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BBIP10 PF14777.6 OWF55064.1 - 1.9e-29 101.0 9.4 5.9e-29 99.4 9.4 1.9 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 Arm PF00514.23 OWF55064.1 - 0.055 13.5 0.9 0.3 11.2 0.1 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OWF55064.1 - 0.13 12.8 0.3 0.59 10.7 0.3 2.3 1 0 0 1 1 1 0 HEAT-like repeat Fes1 PF08609.10 OWF55064.1 - 3 8.8 10.0 0.26 12.2 2.9 2.8 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 PCO_ADO PF07847.12 OWF55065.1 - 1.4e-46 158.5 0.1 1.7e-46 158.2 0.1 1.1 1 0 0 1 1 1 1 PCO_ADO Sugar_tr PF00083.24 OWF55066.1 - 2.8e-100 336.3 30.6 3.5e-100 336.0 30.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF55066.1 - 1.3e-32 113.1 39.4 1.4e-31 109.7 36.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OWF55066.1 - 0.00033 19.1 16.4 0.43 8.8 9.3 3.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_23 PF13489.6 OWF55068.1 - 0.00061 19.7 0.0 0.25 11.1 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OWF55068.1 - 0.14 11.3 0.0 11 5.1 0.0 2.1 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.6 OWF55069.1 - 5.2e-11 43.1 0.0 7.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF55069.1 - 3e-10 40.2 0.0 3.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF55069.1 - 4.5e-10 40.0 0.0 6.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF55069.1 - 1.1e-06 28.5 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF55069.1 - 3.9e-06 27.5 0.0 5.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF55069.1 - 8e-06 25.4 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OWF55069.1 - 6.6e-05 22.5 0.0 0.00014 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 OWF55069.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 OWF55069.1 - 0.0024 17.3 0.1 0.0043 16.5 0.0 1.4 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 OWF55070.1 - 1.5e-11 44.8 0.0 2.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF55070.1 - 6.6e-10 39.5 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF55070.1 - 9.9e-09 35.2 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF55070.1 - 1.1e-08 34.7 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OWF55070.1 - 2.2e-07 30.8 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF55070.1 - 6.5e-06 26.8 0.0 9.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF55070.1 - 0.0017 17.9 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 OWF55070.1 - 0.0022 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DUF4136 PF13590.6 OWF55070.1 - 0.035 14.7 0.0 0.051 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) NodS PF05401.11 OWF55070.1 - 0.08 12.6 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 OWF55070.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MMS19_N PF14500.6 OWF55073.1 - 2.4e-85 286.3 5.2 2.6e-81 273.1 0.0 4.9 3 1 2 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 OWF55073.1 - 3.1e-82 276.9 9.2 3.1e-82 276.9 9.2 2.8 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 OWF55073.1 - 2.3e-09 37.5 3.3 0.067 13.6 0.1 5.3 5 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 OWF55073.1 - 5.3e-08 32.5 8.8 0.036 14.3 0.3 6.6 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 OWF55073.1 - 1.3e-05 25.5 20.7 0.011 16.2 0.1 7.8 7 2 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OWF55073.1 - 0.011 16.4 5.3 7.7 7.2 0.0 5.3 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 OWF55073.1 - 0.015 15.1 7.0 0.72 9.6 0.1 4.1 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) UBD PF16455.5 OWF55074.1 - 2.9e-38 130.3 0.0 7.1e-38 129.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-binding domain ubiquitin PF00240.23 OWF55074.1 - 2.4e-13 49.6 0.0 3.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 OWF55074.1 - 2.9e-05 23.9 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 OWF55074.1 - 4.5e-05 23.2 0.1 7.5e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OWF55074.1 - 0.0044 17.6 0.1 0.0071 16.9 0.1 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HupH_C PF04809.13 OWF55075.1 - 0.0071 16.1 0.2 18 5.0 0.0 4.5 1 1 6 7 7 7 1 HupH hydrogenase expression protein, C-terminal conserved region DUF2249 PF10006.9 OWF55075.1 - 1.8 8.5 13.3 2.2e+02 1.8 0.1 6.8 1 1 5 8 8 8 0 Uncharacterized conserved protein (DUF2249) MA3 PF02847.17 OWF55076.1 - 3.4e-48 162.3 0.1 1e-22 80.2 0.0 2.2 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.15 OWF55076.1 - 0.34 11.8 2.7 1.2 10.0 2.7 1.9 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Xan_ur_permease PF00860.20 OWF55077.1 - 3e-79 266.5 29.1 4.1e-79 266.1 29.1 1.1 1 0 0 1 1 1 1 Permease family zf-C3HC4 PF00097.25 OWF55078.1 - 6.2e-09 35.6 5.9 6.2e-09 35.6 5.9 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF55078.1 - 8.6e-08 32.1 2.4 8.6e-08 32.1 2.4 3.5 3 2 1 4 4 3 1 RING-type zinc-finger zf-B_box PF00643.24 OWF55078.1 - 1.2e-07 31.8 27.2 1.3e-06 28.4 11.2 3.9 4 1 0 4 4 3 2 B-box zinc finger zf-C3HC4_2 PF13923.6 OWF55078.1 - 1.8e-07 30.9 6.7 1.8e-07 30.9 6.7 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF55078.1 - 6.6e-07 29.1 5.7 6.6e-07 29.1 5.7 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF55078.1 - 8.6e-07 29.2 6.6 8.6e-07 29.2 6.6 3.3 3 0 0 3 3 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 OWF55078.1 - 2e-06 27.9 7.9 2e-06 27.9 7.9 3.6 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OWF55078.1 - 2.6e-06 27.3 6.1 2.6e-06 27.3 6.1 3.5 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF55078.1 - 0.00088 19.1 4.3 0.00088 19.1 4.3 3.8 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 OWF55078.1 - 0.0019 17.9 4.3 0.0019 17.9 4.3 3.2 3 0 0 3 3 3 1 MIZ/SP-RING zinc finger Siva PF05458.12 OWF55078.1 - 0.018 14.7 5.7 0.018 14.7 5.7 2.8 2 2 1 3 3 3 0 Cd27 binding protein (Siva) RICH PF05062.12 OWF55079.1 - 1.4e-11 44.6 20.1 18 5.7 0.3 13.5 1 1 7 8 8 8 5 RICH domain UBM PF14377.6 OWF55079.1 - 1.2e-05 24.6 4.6 8.3e+02 -0.3 0.0 12.5 18 0 0 18 18 18 0 Ubiquitin binding region LydB PF16084.5 OWF55079.1 - 0.0016 18.2 9.4 11 5.8 0.2 4.2 1 1 4 5 5 5 5 LydA-holin antagonist zf-H2C2_2 PF13465.6 OWF55080.1 - 2e-38 129.1 61.3 1.2e-08 35.0 3.4 9.8 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 OWF55080.1 - 1.5e-29 100.7 69.8 9.7e-05 22.6 2.9 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF55080.1 - 2.6e-23 80.7 64.8 0.00046 20.8 1.9 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF55080.1 - 1.5e-13 50.6 34.8 0.031 14.6 0.1 7.9 8 0 0 8 8 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF55080.1 - 1.5e-08 34.8 52.3 0.0022 18.3 0.6 8.2 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF55080.1 - 8.8e-07 28.8 59.7 0.011 15.7 2.1 8.4 8 0 0 8 8 8 5 C2H2-type zinc finger zf_UBZ PF18439.1 OWF55080.1 - 0.012 15.2 19.6 2.1 8.0 0.2 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 OWF55080.1 - 0.012 15.9 41.9 0.76 10.1 2.9 6.7 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OWF55080.1 - 0.016 15.0 4.0 0.016 15.0 4.0 7.3 8 0 0 8 8 8 0 zinc-finger C2H2-type BolA PF01722.18 OWF55080.1 - 0.4 11.0 10.8 1.3 9.3 0.2 4.6 4 1 1 5 5 4 0 BolA-like protein zf-C2HE PF16278.5 OWF55080.1 - 1.2 9.7 37.2 1.2 9.6 0.5 7.3 2 1 4 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 OWF55080.1 - 1.6 8.9 27.3 2 8.6 3.0 5.4 3 1 3 6 6 6 0 Zinc ribbon domain GAGA PF09237.11 OWF55080.1 - 5 7.0 21.5 1.8 8.4 0.2 5.3 3 2 2 5 5 5 0 GAGA factor Methyltransf_25 PF13649.6 OWF55082.1 - 2.6e-13 50.5 0.0 4.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF55082.1 - 1.2e-11 45.1 0.0 2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF55082.1 - 7.6e-11 42.0 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF55082.1 - 1.5e-10 41.2 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF55082.1 - 4.1e-06 26.3 0.0 6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OWF55082.1 - 7.3e-05 23.4 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF55082.1 - 0.00057 19.5 0.0 0.00087 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 OWF55082.1 - 0.02 13.5 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 OWF55082.1 - 0.024 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OWF55082.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OWF55083.1 - 3.4e-11 43.6 0.0 5.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF55083.1 - 4e-11 43.0 0.0 5.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF55083.1 - 5.5e-11 43.0 0.0 9.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF55083.1 - 1.1e-07 31.4 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OWF55083.1 - 1.9e-07 31.0 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF55083.1 - 0.001 19.7 0.0 0.0018 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OWF55083.1 - 0.0045 16.1 0.0 0.0059 15.7 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 OWF55083.1 - 0.0091 15.6 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OWF55083.1 - 0.054 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase RabGAP-TBC PF00566.18 OWF55088.1 - 2.5e-48 164.6 2.0 4.6e-48 163.7 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Calreticulin PF00262.18 OWF55089.1 - 0.028 13.3 5.4 0.044 12.7 1.4 2.1 1 1 1 2 2 2 0 Calreticulin family PUB PF09409.10 OWF55089.1 - 0.05 13.5 0.3 6.4 6.8 0.2 3.2 2 1 0 2 2 2 0 PUB domain Transposase_31 PF04754.12 OWF55089.1 - 0.098 12.3 4.4 24 4.5 0.8 3.8 1 1 2 3 3 3 0 Putative transposase, YhgA-like Sad1_UNC PF07738.13 OWF55089.1 - 0.85 9.6 10.3 5.3 7.1 1.1 3.6 1 1 3 4 4 4 0 Sad1 / UNC-like C-terminal FAM53 PF15242.6 OWF55091.1 - 1.2e-18 68.1 30.3 4.9e-18 66.0 30.3 2.3 1 1 0 1 1 1 1 Family of FAM53 SelP_N PF04592.14 OWF55091.1 - 0.15 11.4 13.0 0.24 10.8 13.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ING PF12998.7 OWF55092.1 - 0.043 14.4 0.3 0.98 10.0 0.0 3.1 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Sec15 PF04091.12 OWF55093.1 - 5.4e-96 321.7 2.3 8.5e-96 321.1 1.3 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 OWF55093.1 - 0.14 12.3 0.9 1.5 9.0 0.2 2.9 2 0 0 2 2 2 0 Vps51/Vps67 DUF883 PF05957.13 OWF55093.1 - 0.22 12.2 2.4 38 5.0 0.1 4.4 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) His_Phos_1 PF00300.22 OWF55094.1 - 2.8e-35 121.8 0.0 1.7e-28 99.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) MAM PF00629.23 OWF55095.1 - 1.6e-44 151.7 0.0 2.8e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF3240 PF11582.8 OWF55095.1 - 0.0091 16.1 0.1 0.029 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3240) NADH-UOR_E PF16514.5 OWF55095.1 - 0.21 11.9 0.8 1.4 9.3 0.1 2.5 1 1 1 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E Fez1 PF06818.15 OWF55095.1 - 2.5 8.5 16.6 0.64 10.4 6.4 2.6 1 1 1 2 2 2 0 Fez1 Amidase_2 PF01510.25 OWF55096.1 - 5.1e-17 62.5 0.1 9.1e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase 7tm_1 PF00001.21 OWF55097.1 - 1.1e-33 116.8 15.7 1.4e-33 116.4 15.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF55097.1 - 0.0014 18.4 17.9 0.0014 18.4 17.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Phage_holin_3_6 PF07332.11 OWF55097.1 - 0.16 12.0 6.2 0.54 10.3 1.4 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1980 PF09323.10 OWF55097.1 - 2.1 8.2 13.2 0.89 9.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) 7tm_1 PF00001.21 OWF55098.1 - 3.1e-11 43.1 0.5 3.1e-11 43.1 0.5 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF55098.1 - 0.00069 19.1 0.5 0.00069 19.1 0.5 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Not1 PF04054.15 OWF55098.1 - 0.0029 16.6 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 Neur_chan_LBD PF02931.23 OWF55099.1 - 6.1e-13 48.7 2.0 9.7e-13 48.1 2.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF55099.1 - 7.2e-07 29.5 3.2 7.2e-07 29.5 3.2 2.4 2 1 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region DEP PF00610.21 OWF55100.1 - 7.1e-07 29.2 0.2 5.7e-06 26.3 0.1 2.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pribosyltran_N PF13793.6 OWF55100.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase c-SKI_SMAD_bind PF08782.10 OWF55101.1 - 2.7e-06 27.5 0.1 6.7e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 c-SKI Smad4 binding domain YABBY PF04690.13 OWF55101.1 - 0.028 15.0 1.2 0.25 11.9 1.2 2.7 1 0 0 1 1 1 0 YABBY protein Cnd3 PF12719.7 OWF55102.1 - 3.3e-77 259.6 10.4 3.1e-76 256.4 5.3 2.8 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OWF55102.1 - 3.8e-13 49.6 1.3 0.00042 20.6 0.2 5.2 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 OWF55102.1 - 3.3e-08 33.1 11.7 3.8 8.0 0.0 8.7 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 OWF55102.1 - 7.5e-06 26.1 14.8 0.025 14.6 0.2 5.2 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 UVR PF02151.19 OWF55102.1 - 0.0065 16.2 3.7 0.0065 16.2 3.7 2.0 2 0 0 2 2 2 1 UvrB/uvrC motif Coilin_N PF15862.5 OWF55102.1 - 0.02 14.7 0.0 2.8 7.8 0.1 3.4 3 1 0 3 3 3 0 Coilin N-terminus HEAT_EZ PF13513.6 OWF55102.1 - 0.049 14.1 2.6 1.8 9.1 0.1 4.6 4 1 0 4 4 4 0 HEAT-like repeat Tam41_Mmp37 PF09139.11 OWF55102.1 - 0.5 9.7 3.3 0.22 10.9 0.3 1.9 2 0 0 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial HlyD_2 PF12700.7 OWF55102.1 - 2.6 6.7 8.4 0.51 9.0 1.7 2.1 2 0 0 2 2 2 0 HlyD family secretion protein CBM_14 PF01607.24 OWF55103.1 - 7.3e-12 45.3 32.6 7.6e-07 29.2 8.2 4.2 3 1 1 4 4 4 3 Chitin binding Peritrophin-A domain Laminin_G_2 PF02210.24 OWF55103.1 - 0.047 14.3 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Lig_chan PF00060.26 OWF55104.1 - 4.2e-37 127.3 0.1 6.5e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 OWF55104.1 - 9.9e-34 116.0 0.0 2.2e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 OWF55104.1 - 2.3e-23 82.8 0.0 8.4e-23 81.0 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 OWF55104.1 - 6.4e-11 41.9 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Receptor family ligand binding region S1FA PF04689.13 OWF55104.1 - 0.16 12.2 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 DNA binding protein S1FA Ion_trans_2 PF07885.16 OWF55104.1 - 7.3 6.6 9.7 0.14 12.1 1.6 2.5 2 1 1 3 3 3 0 Ion channel zf-C2H2 PF00096.26 OWF55105.1 - 9.3e-22 76.2 52.0 8.9e-05 22.7 1.4 7.9 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF55105.1 - 2.4e-20 72.0 45.8 1.6e-07 31.4 1.1 8.8 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF55105.1 - 1.9e-13 50.0 53.1 0.039 14.8 2.7 7.8 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_7 PF15269.6 OWF55105.1 - 0.00054 20.0 16.0 0.013 15.5 2.2 3.4 3 0 0 3 3 3 2 Zinc-finger zf-H2C2_5 PF13909.6 OWF55105.1 - 0.0011 18.7 3.4 0.0011 18.7 3.4 5.1 4 1 0 4 4 4 2 C2H2-type zinc-finger domain DUF3268 PF11672.8 OWF55105.1 - 0.0027 18.0 9.1 0.15 12.4 0.2 2.8 2 0 0 2 2 2 2 zinc-finger-containing domain zf-FCS PF06467.14 OWF55105.1 - 0.089 12.7 3.3 10 6.2 0.8 3.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.8 OWF55105.1 - 2.9 8.3 31.6 2.2 8.7 2.1 6.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 OWF55105.1 - 9.6 5.9 18.3 0.035 13.7 0.8 4.7 5 1 0 5 5 5 0 MYST family zinc finger domain BTB PF00651.31 OWF55106.1 - 5.6e-14 52.3 0.1 1.1e-11 44.9 0.1 2.3 1 1 0 1 1 1 1 BTB/POZ domain Pyr_redox_2 PF07992.14 OWF55107.1 - 5.3e-50 170.3 0.0 6.4e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OWF55107.1 - 1.2e-19 70.6 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OWF55107.1 - 5e-19 68.6 0.5 7.9e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OWF55107.1 - 4.2e-07 29.4 2.3 9.1e-07 28.3 2.3 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OWF55107.1 - 1.1e-05 24.8 0.0 0.12 11.6 0.3 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OWF55107.1 - 3.7e-05 23.1 0.1 0.016 14.5 0.0 2.7 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OWF55107.1 - 9.1e-05 21.3 0.4 0.00024 19.9 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 OWF55107.1 - 0.00016 21.0 0.0 0.002 17.3 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OWF55107.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OWF55107.1 - 0.0016 17.9 0.5 0.0029 17.0 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OWF55107.1 - 0.0027 17.4 2.1 0.015 14.9 2.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF55107.1 - 0.0047 17.1 0.2 0.016 15.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OWF55107.1 - 0.0051 16.0 0.6 0.0085 15.2 0.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OWF55107.1 - 0.051 14.0 0.0 0.74 10.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding KH_4 PF13083.6 OWF55107.1 - 0.2 11.6 0.4 5.3 7.0 0.1 2.4 2 0 0 2 2 2 0 KH domain Pyr_redox_dim PF02852.22 OWF55108.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain ABC2_membrane_3 PF12698.7 OWF55109.1 - 3.7 6.6 6.4 23 4.0 3.0 2.4 1 1 1 2 2 2 0 ABC-2 family transporter protein DGOK PF05035.12 OWF55111.1 - 0.19 10.6 0.4 1.8 7.4 0.1 2.2 1 1 1 2 2 2 0 2-keto-3-deoxy-galactonokinase PEX-1N PF09262.11 OWF55111.1 - 2.3 8.7 17.7 54 4.3 0.0 6.7 1 1 3 4 4 4 0 Peroxisome biogenesis factor 1, N-terminal Usp PF00582.26 OWF55114.1 - 6.2e-20 72.1 1.1 2.3e-19 70.3 1.1 1.7 1 1 0 1 1 1 1 Universal stress protein family Ala_racemase_N PF01168.20 OWF55114.1 - 0.029 14.0 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain SpmSyn_N PF17950.1 OWF55114.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal DUF3618 PF12277.8 OWF55114.1 - 0.11 12.7 0.6 0.49 10.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Usp PF00582.26 OWF55115.1 - 2.4e-23 83.2 0.3 8.6e-23 81.4 0.3 1.7 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 OWF55116.1 - 2.1e-23 83.4 0.0 3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family BTB PF00651.31 OWF55117.1 - 2e-23 82.7 2.9 2.6e-23 82.4 1.7 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF55117.1 - 3.3e-15 56.0 0.2 7.4e-15 54.9 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 OWF55117.1 - 3.8e-09 36.0 0.6 1e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 OWF55117.1 - 5.1e-09 36.1 0.7 7.8e-05 22.8 0.0 4.5 2 1 3 5 5 5 1 Kelch motif Kelch_5 PF13854.6 OWF55117.1 - 8.2e-09 35.3 0.0 0.0062 16.5 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OWF55117.1 - 4.1e-06 26.5 0.9 0.0046 16.9 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 OWF55117.1 - 0.00073 19.5 1.1 0.06 13.4 0.3 2.9 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 OWF55117.1 - 0.0012 19.1 2.7 0.13 12.6 0.0 3.8 3 1 0 3 3 3 1 Galactose oxidase, central domain DUF3342 PF11822.8 OWF55117.1 - 0.0055 16.9 0.4 0.013 15.6 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) RAP-1 PF03085.15 OWF55117.1 - 0.027 14.2 0.2 0.06 13.0 0.2 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) V-SNARE_C PF12352.8 OWF55118.1 - 7.7e-13 48.5 0.6 7.7e-13 48.5 0.6 3.5 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus FapA PF03961.13 OWF55118.1 - 0.0021 16.8 2.9 0.0025 16.5 2.9 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 OWF55118.1 - 0.056 13.5 7.3 0.027 14.5 3.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 OWF55118.1 - 0.062 13.7 1.3 0.11 12.9 1.3 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) OmpH PF03938.14 OWF55118.1 - 0.092 13.1 3.8 0.79 10.1 0.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FliJ PF02050.16 OWF55118.1 - 0.12 12.6 7.1 0.039 14.2 2.1 2.5 2 1 1 3 3 3 0 Flagellar FliJ protein DUF2730 PF10805.8 OWF55118.1 - 0.32 11.1 4.5 0.18 11.9 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) LMBR1 PF04791.16 OWF55118.1 - 0.46 9.3 6.5 0.62 8.9 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Synaptonemal_3 PF15191.6 OWF55118.1 - 0.48 10.2 4.3 0.21 11.4 0.5 2.3 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 Occludin_ELL PF07303.13 OWF55118.1 - 0.76 10.5 4.9 4.8 8.0 0.2 2.8 1 1 1 3 3 3 0 Occludin homology domain Rho_Binding PF08912.11 OWF55118.1 - 0.84 10.5 4.5 8.3 7.3 0.1 3.4 2 1 3 5 5 5 0 Rho Binding ABC_tran_CTD PF16326.5 OWF55118.1 - 1.8 8.8 7.2 0.34 11.2 1.3 2.8 3 1 0 3 3 3 0 ABC transporter C-terminal domain GFA PF04828.14 OWF55119.1 - 5e-09 36.4 2.7 5e-09 36.4 2.7 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme AIG1 PF04548.16 OWF55120.1 - 1.1e-25 90.2 0.3 2.3e-25 89.2 0.1 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 OWF55120.1 - 1.4e-08 34.8 0.0 5.6e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OWF55120.1 - 2.5e-06 27.7 0.8 0.0072 16.4 0.1 3.1 1 1 2 3 3 3 2 Dynamin family Gtr1_RagA PF04670.12 OWF55120.1 - 9.4e-06 25.1 0.0 3.5e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OWF55120.1 - 0.0002 20.9 0.0 0.00049 19.6 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF2795 PF11387.8 OWF55120.1 - 0.0092 16.2 0.0 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2795) DEAD_assoc PF08494.11 OWF55120.1 - 0.025 14.4 0.2 0.054 13.3 0.2 1.5 1 0 0 1 1 1 0 DEAD/H associated VPS28 PF03997.12 OWF55120.1 - 0.21 11.2 3.3 0.29 10.8 3.3 1.3 1 0 0 1 1 1 0 VPS28 protein F-box-like PF12937.7 OWF55121.1 - 1.2e-06 28.3 4.1 1.2e-06 28.3 4.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OWF55121.1 - 2.6e-05 23.9 5.1 7e-05 22.6 0.6 3.2 3 0 0 3 3 3 1 F-box domain Vma12 PF11712.8 OWF55122.1 - 3.7e-23 82.1 0.0 4.7e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase M PF02370.16 OWF55122.1 - 0.27 11.9 1.2 0.67 10.7 1.2 1.6 1 0 0 1 1 1 0 M protein repeat DUF4407 PF14362.6 OWF55122.1 - 0.59 9.4 7.1 4.5 6.5 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DRY_EERY PF09750.9 OWF55123.1 - 2.1e-28 99.3 1.9 2.1e-28 99.3 1.9 4.2 3 0 0 3 3 3 1 Alternative splicing regulator Surp PF01805.20 OWF55123.1 - 3.5e-26 90.9 4.5 3.6e-13 49.3 0.3 2.5 2 0 0 2 2 2 2 Surp module PSP PF04046.16 OWF55123.1 - 7e-15 54.6 0.2 2e-14 53.2 0.2 1.9 1 0 0 1 1 1 1 PSP Amidase PF01425.21 OWF55125.1 - 1.3e-67 228.7 0.0 1.9e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Amidase OTU PF02338.19 OWF55126.1 - 1e-14 55.1 0.0 2.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease zf-A20 PF01754.16 OWF55126.1 - 3.9e-10 39.5 74.7 4.3e-06 26.6 8.4 7.5 7 0 0 7 7 7 4 A20-like zinc finger MOLO1 PF17175.4 OWF55127.1 - 6.3e-25 87.6 0.0 9.5e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 OWF55127.1 - 5.1e-09 36.4 0.0 1.3e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 TPM domain COX6C PF02937.15 OWF55127.1 - 0.63 10.2 0.0 0.63 10.2 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Y_phosphatase PF00102.27 OWF55128.1 - 7.8e-75 251.5 0.5 1.6e-74 250.4 0.5 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 OWF55128.1 - 1.3e-27 96.0 14.3 1.9e-08 34.5 0.1 5.6 5 1 0 5 5 4 4 Fibronectin type III domain DUF2369 PF10179.9 OWF55128.1 - 0.00014 22.2 3.5 2.5 8.5 0.0 4.0 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) Protocadherin PF08374.11 OWF55128.1 - 0.0026 17.8 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Protocadherin DSPc PF00782.20 OWF55128.1 - 0.0048 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OWF55128.1 - 0.0053 16.9 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF5305 PF17231.2 OWF55128.1 - 0.0075 15.7 0.1 0.15 11.5 0.1 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Y_phosphatase3 PF13350.6 OWF55128.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family EphA2_TM PF14575.6 OWF55128.1 - 0.062 14.2 0.0 0.24 12.3 0.0 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 OWF55128.1 - 0.12 12.5 1.5 0.23 11.5 1.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pur_ac_phosph_N PF16656.5 OWF55128.1 - 1.1 9.8 13.3 1.4 9.5 0.1 4.9 4 2 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain GPI-anchored PF10342.9 OWF55128.1 - 1.6 9.5 11.6 1.4 9.8 0.6 4.8 6 0 0 6 6 6 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA PF00004.29 OWF55129.1 - 3.8e-41 140.6 0.0 6.3e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OWF55129.1 - 2.8e-28 97.7 0.1 1.1e-27 95.8 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OWF55129.1 - 4.4e-24 84.3 8.2 1.1e-23 83.1 8.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OWF55129.1 - 3.9e-07 29.8 0.0 1.2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OWF55129.1 - 4.2e-06 27.1 0.0 0.0067 16.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OWF55129.1 - 1.7e-05 24.7 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 OWF55129.1 - 6.1e-05 23.5 0.1 0.0071 16.8 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OWF55129.1 - 6.8e-05 22.9 0.0 0.00023 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OWF55129.1 - 0.00012 22.1 0.0 0.00038 20.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 OWF55129.1 - 0.00023 21.0 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OWF55129.1 - 0.0004 19.7 0.0 0.00081 18.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OWF55129.1 - 0.00071 19.7 0.0 0.0021 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 OWF55129.1 - 0.0011 19.5 0.0 0.0046 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OWF55129.1 - 0.0025 17.0 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 OWF55129.1 - 0.0065 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OWF55129.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OWF55129.1 - 0.014 15.8 0.0 0.051 14.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 OWF55129.1 - 0.02 14.6 0.0 0.12 12.1 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 OWF55129.1 - 0.021 15.3 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OWF55129.1 - 0.031 13.8 0.0 0.075 12.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OWF55129.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 OWF55129.1 - 0.036 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OWF55129.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 OWF55129.1 - 0.053 13.4 0.0 0.43 10.5 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 OWF55129.1 - 0.07 12.4 0.0 2.1 7.6 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin AAA_25 PF13481.6 OWF55129.1 - 0.077 12.6 0.1 1.4 8.4 0.1 2.3 1 1 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 OWF55129.1 - 0.12 12.0 0.3 1.5 8.4 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase YhdB PF14148.6 OWF55129.1 - 0.12 12.5 0.6 0.25 11.5 0.6 1.5 1 0 0 1 1 1 0 YhdB-like protein TPR_2 PF07719.17 OWF55129.1 - 0.15 12.3 0.3 0.93 9.8 0.2 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat Cupin_8 PF13621.6 OWF55130.1 - 2.8e-42 145.2 0.1 4.5e-42 144.5 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OWF55130.1 - 7.3e-10 38.8 0.1 1.9e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OWF55130.1 - 0.0012 19.2 0.0 0.004 17.6 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OWF55130.1 - 0.059 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Tyrosinase PF00264.20 OWF55131.1 - 3.3e-27 96.2 3.8 1.6e-14 54.7 0.9 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase APG6_N PF17675.1 OWF55132.1 - 0.045 14.3 0.4 0.045 14.3 0.4 4.1 4 1 0 4 4 4 0 Apg6 coiled-coil region DUF1484 PF07363.11 OWF55132.1 - 0.072 14.1 1.1 0.21 12.6 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) ECH_1 PF00378.20 OWF55133.1 - 1.5e-30 106.4 0.0 1.7e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF55133.1 - 8.6e-09 35.3 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AOX PF01786.17 OWF55133.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Alternative oxidase ECH_1 PF00378.20 OWF55134.1 - 1.8e-29 102.8 0.0 2.2e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF55134.1 - 5.3e-13 49.2 0.0 6e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OWF55134.1 - 0.034 14.1 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Lipocalin_2 PF08212.12 OWF55135.1 - 1.6e-23 83.3 0.0 2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF55135.1 - 8.5e-13 48.7 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 OWF55135.1 - 0.07 12.6 0.1 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 VDE lipocalin domain DUF5521 PF17659.1 OWF55135.1 - 0.11 10.3 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Lipocalin_2 PF08212.12 OWF55136.1 - 4.9e-20 72.0 0.0 5.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 OWF55136.1 - 1.9e-14 54.1 0.0 2.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 OWF55136.1 - 0.0057 16.2 0.1 0.011 15.3 0.1 1.4 1 1 0 1 1 1 1 VDE lipocalin domain Triabin PF03973.13 OWF55136.1 - 0.034 14.0 1.2 0.16 11.8 1.2 2.2 1 1 0 1 1 1 0 Triabin DUF5521 PF17659.1 OWF55136.1 - 0.041 11.7 0.0 0.057 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) PAP_assoc PF03828.19 OWF55137.1 - 7.2e-18 64.6 0.0 1.9e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OWF55137.1 - 2e-15 56.9 0.1 3.7e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OWF55137.1 - 0.0021 18.1 0.0 0.0051 16.9 0.0 1.7 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF3439 PF11921.8 OWF55137.1 - 9 6.3 8.7 22 5.0 8.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 OWF55138.1 - 5.5e-22 78.4 0.0 8.3e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55138.1 - 3.3e-21 75.8 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 OWF55138.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ank_2 PF12796.7 OWF55140.1 - 4.7e-64 213.0 33.8 5.2e-15 55.8 2.9 5.9 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55140.1 - 3.6e-44 148.6 14.7 3.6e-08 33.8 0.1 9.3 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 OWF55140.1 - 3.7e-44 147.3 19.5 3e-05 24.3 0.1 9.0 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 OWF55140.1 - 1.8e-41 139.7 12.9 9.1e-12 45.0 0.2 7.5 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55140.1 - 1.4e-33 111.1 11.3 0.0014 19.0 0.0 9.1 8 0 0 8 8 8 8 Ankyrin repeat VPS9 PF02204.18 OWF55140.1 - 1.5e-21 76.5 0.0 4.7e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain UvrB PF12344.8 OWF55140.1 - 0.02 14.7 1.2 0.09 12.6 0.2 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B 7tm_3 PF00003.22 OWF55141.1 - 2.9e-42 145.0 20.7 3.9e-42 144.6 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DHHC PF01529.20 OWF55142.1 - 3.3e-37 127.6 15.6 3.3e-37 127.6 15.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase RNase_PH PF01138.21 OWF55143.1 - 1.3e-21 77.5 0.0 2.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OWF55143.1 - 5.6e-11 42.3 0.3 2e-09 37.4 0.2 3.0 3 1 1 4 4 4 1 3' exoribonuclease family, domain 2 ZapB PF06005.12 OWF55144.1 - 5.2e-06 26.8 19.3 0.00081 19.8 3.3 3.5 3 1 0 3 3 3 3 Cell division protein ZapB bZIP_1 PF00170.21 OWF55144.1 - 0.0013 18.8 15.1 0.53 10.4 0.3 3.8 4 0 0 4 4 3 2 bZIP transcription factor DivIC PF04977.15 OWF55144.1 - 0.047 13.5 22.3 0.36 10.6 2.2 4.0 3 1 1 4 4 4 0 Septum formation initiator GAS PF13851.6 OWF55144.1 - 0.068 12.5 25.2 0.72 9.2 8.4 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.13 OWF55144.1 - 0.069 12.3 19.4 0.22 10.7 0.1 2.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region PRKG1_interact PF15898.5 OWF55144.1 - 0.071 14.0 23.8 0.34 11.8 13.0 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4391 PF14335.6 OWF55144.1 - 0.086 12.5 16.9 0.22 11.2 3.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4391) CCDC144C PF14915.6 OWF55144.1 - 0.13 11.3 21.3 1 8.4 0.4 3.0 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region DUF724 PF05266.14 OWF55144.1 - 0.13 12.1 19.8 0.058 13.2 6.7 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF724) YabA PF06156.13 OWF55144.1 - 0.25 12.0 17.4 5.5 7.7 0.2 3.5 2 1 1 3 3 3 0 Initiation control protein YabA Dynactin_p22 PF07426.11 OWF55144.1 - 0.32 10.8 12.0 0.43 10.4 2.1 3.2 3 0 0 3 3 3 0 Dynactin subunit p22 FAM76 PF16046.5 OWF55144.1 - 0.33 10.3 21.2 0.58 9.5 21.2 1.4 1 0 0 1 1 1 0 FAM76 protein Cnn_1N PF07989.11 OWF55144.1 - 0.42 10.8 21.6 0.19 11.9 4.0 3.8 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 OWF55144.1 - 0.7 10.3 12.6 2.2 8.8 4.0 4.0 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) USP8_interact PF08941.10 OWF55144.1 - 0.71 9.7 6.3 0.58 9.9 2.0 2.2 2 0 0 2 2 2 0 USP8 interacting DUF4140 PF13600.6 OWF55144.1 - 0.74 10.3 12.1 4.2 7.9 0.5 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 OWF55144.1 - 0.77 9.8 24.0 0.45 10.6 6.6 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 OWF55144.1 - 0.83 10.3 10.8 0.52 11.0 0.7 3.6 3 1 0 3 3 3 0 SlyX Mst1_SARAH PF11629.8 OWF55144.1 - 0.87 9.7 7.0 63 3.8 3.9 3.8 2 2 1 3 3 3 0 C terminal SARAH domain of Mst1 Spc24 PF08286.11 OWF55144.1 - 1.1 9.5 16.3 5 7.4 0.3 3.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 HTH_Tnp_1 PF01527.20 OWF55144.1 - 3 8.2 7.4 32 4.9 0.0 3.8 4 1 0 4 4 3 0 Transposase DUF1664 PF07889.12 OWF55144.1 - 3.2 7.8 12.3 0.9 9.6 4.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Mto2_bdg PF12808.7 OWF55144.1 - 4 7.8 9.8 7 7.0 0.5 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Macoilin PF09726.9 OWF55144.1 - 4.9 5.6 22.3 0.3 9.6 15.5 1.8 1 1 1 2 2 2 0 Macoilin family APG6_N PF17675.1 OWF55144.1 - 5.1 7.6 26.5 13 6.3 4.7 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region CSN5_C PF18323.1 OWF55144.1 - 5.3 8.0 11.7 9.1 7.3 5.8 2.5 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain TMF_DNA_bd PF12329.8 OWF55144.1 - 5.5 7.1 29.7 0.62 10.1 7.0 4.5 4 2 0 4 4 4 0 TATA element modulatory factor 1 DNA binding CtIP_N PF10482.9 OWF55144.1 - 9.2 6.3 18.4 6.4 6.9 13.4 2.7 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain CN_hydrolase PF00795.22 OWF55145.1 - 2.8e-12 46.6 0.0 3.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Actin PF00022.19 OWF55146.1 - 5.9e-107 357.8 0.0 2.9e-106 355.5 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OWF55146.1 - 0.00034 19.5 0.0 0.0017 17.3 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 OWF55146.1 - 0.02 15.3 0.0 0.36 11.3 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA DSPc PF00782.20 OWF55147.1 - 7.4e-58 194.1 1.7 4.2e-28 97.8 0.1 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF55147.1 - 3.7e-10 39.8 0.1 4.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CDKN3 PF05706.12 OWF55147.1 - 1e-06 28.6 0.9 0.014 15.1 0.1 2.2 2 0 0 2 2 2 2 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 OWF55147.1 - 0.00069 19.9 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 2 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 OWF55147.1 - 0.015 15.5 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Pro-kuma_activ PF09286.11 OWF55147.1 - 0.049 13.9 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain PIG-U PF06728.13 OWF55148.1 - 6.4e-108 361.2 39.4 7.7e-108 360.9 39.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U F-box PF00646.33 OWF55148.1 - 0.079 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box domain TIR PF01582.20 OWF55149.1 - 5.8e-16 58.8 0.5 1.4e-15 57.6 0.5 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF55149.1 - 1.5e-14 54.6 0.1 3.5e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 OWF55149.1 - 4.4e-05 23.2 0.7 0.34 10.7 0.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat DUF1863 PF08937.11 OWF55149.1 - 0.00068 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.7 OWF55149.1 - 0.0022 18.3 1.0 3.2 8.3 0.4 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF55149.1 - 0.0026 18.1 0.4 30 5.7 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat NOG1_N PF17835.1 OWF55149.1 - 0.031 14.2 0.2 0.058 13.4 0.2 1.4 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Meis_PKNOX_N PF16493.5 OWF55149.1 - 0.066 13.6 0.0 0.26 11.6 0.0 2.0 1 1 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 LRR_6 PF13516.6 OWF55149.1 - 0.28 11.3 0.9 21 5.5 0.3 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Tyrosinase PF00264.20 OWF55150.1 - 6.6e-25 88.7 0.7 2.3e-11 44.4 0.0 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase FancD2 PF14631.6 OWF55150.1 - 0.15 9.5 0.1 0.19 9.1 0.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease VWD PF00094.25 OWF55152.1 - 2.9e-18 66.7 0.5 4.2e-18 66.1 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain YabP PF07873.11 OWF55152.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 YabP family Cthe_2159 PF14262.6 OWF55152.1 - 0.075 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 DUF1943 PF09172.11 OWF55153.1 - 4.4e-69 233.1 0.7 1.5e-68 231.3 0.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Vitellogenin_N PF01347.22 OWF55153.1 - 1.8e-26 92.7 0.0 2.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1081 PF06448.11 OWF55153.1 - 3.5e-14 53.2 0.2 1.3e-12 48.1 0.0 3.9 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1081) Ank_2 PF12796.7 OWF55154.1 - 1.3e-18 67.4 0.2 1.8e-09 38.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF55154.1 - 1.2e-17 63.4 0.6 0.00034 20.9 0.3 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OWF55154.1 - 4e-17 62.1 0.2 8.1e-08 32.4 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55154.1 - 8.2e-15 53.5 0.1 0.00025 21.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OWF55154.1 - 3.5e-13 49.8 0.1 6.3e-07 29.8 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (many copies) dNK PF01712.19 OWF55155.1 - 1.2e-60 204.9 4.8 1.4e-60 204.6 4.8 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 OWF55155.1 - 0.00017 22.1 0.2 0.0013 19.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OWF55155.1 - 0.00068 19.8 0.1 0.023 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 OWF55155.1 - 0.00083 18.6 0.6 0.0014 17.8 0.6 1.6 1 1 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.6 OWF55155.1 - 0.0057 17.1 1.3 0.039 14.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain GTP_EFTU PF00009.27 OWF55155.1 - 0.0075 15.8 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Thymidylate_kin PF02223.17 OWF55155.1 - 0.0093 15.7 0.6 0.029 14.0 0.6 1.9 1 1 0 1 1 1 1 Thymidylate kinase TsaE PF02367.17 OWF55155.1 - 0.028 14.4 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Herpes_TK PF00693.18 OWF55155.1 - 0.068 12.4 0.1 0.16 11.1 0.0 1.7 1 1 1 2 2 2 0 Thymidine kinase from herpesvirus CoaE PF01121.20 OWF55155.1 - 0.075 12.7 0.0 0.45 10.2 0.0 2.2 3 0 0 3 3 3 0 Dephospho-CoA kinase ECH_1 PF00378.20 OWF55156.1 - 1.2e-29 103.4 0.0 1.4e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OWF55156.1 - 1.9e-12 47.3 0.3 4.2e-12 46.2 0.1 1.6 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Tyrosinase PF00264.20 OWF55157.1 - 7.1e-24 85.3 0.3 3.4e-11 43.9 0.6 2.6 1 1 1 2 2 2 2 Common central domain of tyrosinase LBP_BPI_CETP_C PF02886.17 OWF55158.1 - 1.6e-28 99.8 0.3 3.6e-28 98.6 0.1 1.6 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain Tyrosinase PF00264.20 OWF55158.1 - 1.6e-26 94.0 6.1 9e-25 88.3 6.1 2.5 1 1 0 1 1 1 1 Common central domain of tyrosinase LBP_BPI_CETP PF01273.25 OWF55158.1 - 1.4e-20 73.5 0.1 2.6e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Tyrosinase PF00264.20 OWF55159.1 - 4e-08 33.8 2.0 2.9e-05 24.5 0.0 2.7 1 1 1 2 2 2 2 Common central domain of tyrosinase ADPrib_exo_Tox PF03496.14 OWF55159.1 - 0.087 12.2 0.3 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Tyrosinase PF00264.20 OWF55160.1 - 9.3e-20 71.9 4.1 1.2e-16 61.7 4.1 2.6 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF2258 PF10015.9 OWF55160.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Ubiq_cyt_C_chap PF03981.12 OWF55160.1 - 0.21 11.6 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Tyrosinase PF00264.20 OWF55161.1 - 1.2e-22 81.3 3.7 7.7e-20 72.1 1.3 2.7 2 1 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OWF55162.1 - 1.8e-24 87.2 5.2 9.8e-22 78.3 2.4 2.8 2 1 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OWF55163.1 - 3.9e-24 86.2 8.5 4.9e-13 49.9 3.8 2.8 2 1 1 3 3 3 2 Common central domain of tyrosinase zf-IS66 PF13005.7 OWF55163.1 - 0.046 14.1 1.0 0.15 12.5 1.0 1.9 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 Tyrosinase PF00264.20 OWF55164.1 - 3.8e-31 109.1 4.2 3.8e-31 109.1 4.2 3.2 2 1 0 2 2 2 1 Common central domain of tyrosinase Prok-RING_1 PF14446.6 OWF55164.1 - 0.16 12.0 0.4 0.3 11.0 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SNF PF00209.18 OWF55165.1 - 1.1e-153 512.7 26.1 1.5e-153 512.3 26.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family HECT PF00632.25 OWF55167.1 - 0.12 11.9 0.0 2.4 7.6 0.0 2.3 2 1 1 3 3 3 0 HECT-domain (ubiquitin-transferase) IFN-gamma PF00714.17 OWF55168.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Interferon gamma Ank_2 PF12796.7 OWF55170.1 - 3.4e-42 142.9 0.0 2.5e-15 56.8 0.0 5.1 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55170.1 - 3.1e-24 85.0 0.6 3.9e-09 36.9 0.0 7.5 4 1 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF55170.1 - 4.7e-20 71.1 3.8 1.5e-06 28.3 0.0 8.2 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 OWF55170.1 - 2.1e-19 67.6 4.6 2e-05 24.6 0.0 9.3 9 1 1 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 OWF55170.1 - 2.3e-17 62.8 0.2 1.8e-06 28.1 0.0 6.2 4 2 3 7 7 7 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 OWF55170.1 - 0.012 15.9 0.3 0.026 14.9 0.3 1.5 1 0 0 1 1 1 0 SOCS box Ank_2 PF12796.7 OWF55171.1 - 4.2e-42 142.6 2.2 6.5e-13 49.1 0.0 4.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55171.1 - 7.8e-27 93.3 5.1 0.00039 20.9 0.0 7.3 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 OWF55171.1 - 2.5e-25 87.8 5.9 0.0057 17.0 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 OWF55171.1 - 1.3e-22 79.5 5.2 0.00035 20.8 0.1 7.3 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55171.1 - 5.3e-20 69.4 9.7 0.18 12.5 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat SOCS_box PF07525.16 OWF55171.1 - 0.00049 20.4 0.4 0.00049 20.4 0.4 3.0 4 0 0 4 4 4 1 SOCS box GILT PF03227.16 OWF55171.1 - 0.094 13.0 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Ank_2 PF12796.7 OWF55172.1 - 1.8e-30 105.4 0.6 6.8e-10 39.4 0.0 5.0 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 OWF55172.1 - 1.6e-21 75.7 9.9 0.0031 17.9 0.0 8.8 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 OWF55172.1 - 1.5e-20 73.0 7.7 0.0004 20.6 0.1 6.5 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF55172.1 - 1.9e-18 66.5 5.1 3.1e-05 24.4 0.0 6.5 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55172.1 - 7.7e-17 59.7 11.3 0.15 12.7 0.0 9.8 11 0 0 11 11 11 4 Ankyrin repeat SOCS_box PF07525.16 OWF55172.1 - 0.00083 19.7 1.7 0.0031 17.8 0.0 2.7 3 0 0 3 3 3 1 SOCS box VWD PF00094.25 OWF55174.1 - 5.1e-10 39.8 1.2 5.1e-10 39.8 1.2 2.9 2 1 0 2 2 2 1 von Willebrand factor type D domain EGF_2 PF07974.13 OWF55174.1 - 0.014 15.7 13.3 0.014 15.7 13.3 4.7 5 0 0 5 5 5 0 EGF-like domain NDUF_B6 PF09782.9 OWF55174.1 - 0.063 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit EGF_Tenascin PF18720.1 OWF55174.1 - 1.2 9.3 20.3 0.25 11.4 15.4 2.7 2 0 0 2 2 2 0 Tenascin EGF domain HtrL_YibB PF09612.10 OWF55175.1 - 1.9e-19 70.2 5.4 3.1e-19 69.5 5.4 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) EFP PF01132.20 OWF55175.1 - 0.0064 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF3972 PF13118.6 OWF55176.1 - 0.014 15.8 0.1 8 6.9 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3972) UPF0184 PF03670.13 OWF55176.1 - 0.016 15.6 5.2 33 4.9 0.2 4.2 1 1 4 5 5 5 0 Uncharacterised protein family (UPF0184) Hrs_helical PF12210.8 OWF55176.1 - 0.21 12.2 1.0 20 5.8 0.1 3.1 1 1 3 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate YfiO PF13525.6 OWF55176.1 - 0.43 10.3 2.9 5.1 6.8 0.2 2.3 1 1 1 2 2 2 0 Outer membrane lipoprotein DUF4744 PF15918.5 OWF55176.1 - 0.8 10.6 4.7 92 4.0 4.7 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) EF-hand_11 PF08976.11 OWF55176.1 - 0.93 10.4 6.4 30 5.6 1.7 3.5 1 1 1 2 2 2 0 EF-hand domain KorB PF08535.10 OWF55176.1 - 6.6 6.8 7.9 35 4.5 0.6 3.5 1 1 2 3 3 3 0 KorB domain YfiO PF13525.6 OWF55177.1 - 0.00096 18.9 4.0 0.21 11.3 0.8 2.1 1 1 1 2 2 2 2 Outer membrane lipoprotein FadA PF09403.10 OWF55177.1 - 0.0025 18.3 0.0 1.5 9.4 0.0 2.4 1 1 1 2 2 2 2 Adhesion protein FadA UPF0184 PF03670.13 OWF55177.1 - 0.0046 17.3 0.0 2.3 8.7 0.0 2.3 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0184) Phage_DsbA PF11126.8 OWF55177.1 - 0.011 15.9 5.1 12 6.2 0.3 4.5 2 2 1 3 3 3 0 Transcriptional regulator DsbA POX PF07526.11 OWF55177.1 - 0.015 15.9 7.7 0.095 13.3 1.2 2.4 1 1 1 2 2 2 0 Associated with HOX UPF0223 PF05256.12 OWF55177.1 - 0.019 15.3 7.5 8.9 6.7 1.3 3.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0223) EF-hand_11 PF08976.11 OWF55177.1 - 0.036 14.9 2.9 8.5 7.3 0.4 2.8 1 1 1 2 2 2 0 EF-hand domain DUF1796 PF08795.10 OWF55177.1 - 0.042 13.8 0.0 0.32 11.0 0.0 2.0 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) VP9 PF09625.10 OWF55177.1 - 0.44 10.7 12.9 4 7.7 0.5 4.1 1 1 3 4 4 4 0 VP9 protein KorB PF08535.10 OWF55177.1 - 1.1 9.3 3.1 16 5.7 0.8 2.5 1 1 1 2 2 2 0 KorB domain DUF3989 PF13150.6 OWF55177.1 - 3.3 7.5 13.4 19 5.1 0.1 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3989) FliE PF02049.18 OWF55177.1 - 9 6.5 8.1 4.9 7.4 2.5 2.2 1 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF1445 PF07286.12 OWF55177.1 - 9.7 6.1 12.9 25 4.8 1.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1445) EF-hand_11 PF08976.11 OWF55178.1 - 0.0022 18.8 3.9 0.72 10.8 0.1 3.2 1 1 2 3 3 3 1 EF-hand domain UPF0184 PF03670.13 OWF55178.1 - 0.003 17.9 0.3 10 6.6 0.1 3.5 1 1 3 4 4 4 2 Uncharacterised protein family (UPF0184) Adeno_IVa2 PF02456.15 OWF55178.1 - 0.021 13.6 0.9 3 6.5 0.1 2.8 1 1 1 2 2 2 0 Adenovirus IVa2 protein DHR-2 PF06920.13 OWF55178.1 - 0.046 12.4 0.3 1.9 7.0 0.1 2.0 1 1 1 2 2 2 0 Dock homology region 2 Phage_DsbA PF11126.8 OWF55178.1 - 0.061 13.5 7.4 7.2e+02 0.5 7.4 4.9 1 1 0 1 1 1 0 Transcriptional regulator DsbA DUF4744 PF15918.5 OWF55178.1 - 0.15 12.9 2.3 5.1 8.0 2.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) HAUS4 PF14735.6 OWF55178.1 - 0.23 11.2 0.5 11 5.6 0.0 2.8 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 4 YfiO PF13525.6 OWF55178.1 - 0.35 10.6 4.9 3.4 7.3 0.4 2.2 1 1 1 2 2 2 0 Outer membrane lipoprotein VP9 PF09625.10 OWF55178.1 - 7.5 6.8 14.0 19 5.5 0.4 4.6 1 1 2 3 3 3 0 VP9 protein HtrL_YibB PF09612.10 OWF55179.1 - 1.2e-18 67.7 3.9 2.5e-18 66.6 3.9 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) TRH PF05438.12 OWF55180.1 - 0.19 11.5 22.8 0.83 9.4 6.5 2.8 1 1 2 3 3 3 0 Thyrotropin-releasing hormone (TRH) CshA_NR2 PF18651.1 OWF55180.1 - 0.65 9.1 8.8 0.055 12.7 2.5 1.8 1 1 0 2 2 2 0 Surface adhesin CshA non-repetitive domain 2 BDM PF10684.9 OWF55180.1 - 1.2 9.5 2.8 41 4.6 0.1 3.6 2 1 2 4 4 4 0 Putative biofilm-dependent modulation protein Tombus_P33 PF08500.10 OWF55180.1 - 2.8 7.9 12.9 3.9 7.4 1.4 3.3 1 1 1 3 3 3 0 Tombusvirus p33 Adeno_E1B_55K_N PF04623.12 OWF55181.1 - 0.0047 17.6 2.2 12 6.7 0.0 3.2 2 1 1 3 3 3 3 Adenovirus E1B protein N-terminus Flavi_M PF01004.19 OWF55181.1 - 0.5 10.2 2.7 9 6.1 0.2 2.5 1 1 1 2 2 2 0 Flavivirus envelope glycoprotein M Angiomotin_C PF12240.8 OWF55182.1 - 5.3e-31 107.8 33.8 2.7e-22 79.4 14.2 3.7 3 1 1 4 4 4 3 Angiomotin C terminal Lzipper-MIP1 PF14389.6 OWF55182.1 - 0.56 10.5 29.7 0.77 10.1 0.1 4.6 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 KIP1 PF07765.12 OWF55182.1 - 7.4 6.8 9.1 3.9 7.7 1.5 3.5 3 1 0 3 3 3 0 KIP1-like protein bZIP_Maf PF03131.17 OWF55183.1 - 0.12 12.9 11.2 0.24 11.9 11.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2231 PF09990.9 OWF55184.1 - 0.021 15.3 3.0 0.043 14.3 3.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) BacA PF02673.18 OWF55184.1 - 0.027 14.2 1.7 0.033 13.9 0.7 1.6 1 1 1 2 2 2 0 Bacitracin resistance protein BacA FixQ PF05545.11 OWF55184.1 - 0.044 13.8 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF1616 PF07760.11 OWF55184.1 - 0.049 13.0 0.8 0.21 10.9 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) DUF4131 PF13567.6 OWF55184.1 - 0.43 10.2 3.3 0.28 10.8 1.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2178 PF09946.9 OWF55184.1 - 0.59 10.3 6.5 2.7 8.2 4.5 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) Yippee-Mis18 PF03226.14 OWF55185.1 - 1.1e-12 48.1 0.1 1.3e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 OWF55185.1 - 0.0003 20.9 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 OWF55185.1 - 0.0059 16.8 0.0 0.0087 16.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I HNH_5 PF14279.6 OWF55185.1 - 0.085 12.7 0.1 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease PriA_CRR PF18319.1 OWF55185.1 - 1.4 9.0 3.9 11 6.1 0.1 2.3 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain DUF5600 PF18150.1 OWF55186.1 - 8.2e-45 151.8 1.2 1.7e-44 150.8 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 OWF55186.1 - 2e-20 72.7 0.3 5.2e-20 71.3 0.3 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 OWF55186.1 - 1e-16 60.5 3.6 1e-16 60.5 3.6 3.0 4 0 0 4 4 4 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 OWF55186.1 - 1.1e-12 48.3 0.0 3.2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OWF55186.1 - 1.6e-06 28.2 0.0 3.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 OWF55186.1 - 0.011 15.2 0.1 0.074 12.6 0.1 2.5 1 0 0 1 1 1 0 EF hand AAA_28 PF13521.6 OWF55186.1 - 0.023 14.9 0.0 0.065 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OWF55186.1 - 0.045 14.0 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OWF55186.1 - 0.049 13.0 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OWF55186.1 - 0.086 12.7 0.0 4.2 7.2 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase RNA_pol_A_bac PF01000.26 OWF55187.1 - 6.8e-33 113.4 0.0 1.1e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OWF55187.1 - 2.2e-23 81.4 0.0 3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Clat_adaptor_s PF01217.20 OWF55188.1 - 1.7e-62 209.5 8.2 1.9e-62 209.4 8.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RhoGAP PF00620.27 OWF55189.1 - 1e-32 113.1 0.6 2.5e-32 111.8 0.6 1.7 1 0 0 1 1 1 1 RhoGAP domain DUF3046 PF11248.8 OWF55190.1 - 0.0017 18.7 0.1 5.9 7.3 0.0 3.5 1 1 1 3 3 3 3 Protein of unknown function (DUF3046) Cuticle_3 PF11018.8 OWF55191.1 - 1.3e-06 28.8 30.4 15 5.7 1.2 8.4 1 1 13 14 14 14 14 Pupal cuticle protein C1 UPF0051 PF01458.17 OWF55192.1 - 0.0078 15.9 0.4 0.0097 15.6 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Nodulin_late PF07127.11 OWF55192.1 - 4 7.9 10.7 4 7.9 0.2 2.4 2 1 0 2 2 2 0 Late nodulin protein RasGEF PF00617.19 OWF55193.1 - 1e-46 159.4 1.6 2.1e-46 158.4 1.6 1.6 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.22 OWF55193.1 - 1.2e-12 47.5 9.1 3.2e-12 46.2 9.1 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_5 PF13202.6 OWF55193.1 - 3.7e-10 38.8 3.8 4e-05 22.9 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 OWF55193.1 - 1e-09 37.3 4.2 5.8e-05 22.4 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OWF55193.1 - 6.9e-09 34.9 0.9 0.00015 21.4 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF55193.1 - 1.4e-07 31.8 0.4 0.0029 18.0 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair RasGEF_N PF00618.20 OWF55193.1 - 1.5e-07 31.6 0.0 5.4e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_U57 PF05582.12 OWF55193.1 - 0.0027 17.0 2.7 0.0046 16.3 2.7 1.2 1 0 0 1 1 1 1 YabG peptidase U57 EF-hand_8 PF13833.6 OWF55193.1 - 0.028 14.2 2.7 4.9 7.1 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair Cofac_haem_bdg PF04187.13 OWF55193.1 - 0.042 13.8 1.0 2.6 8.0 1.3 2.2 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN SPARC_Ca_bdg PF10591.9 OWF55193.1 - 0.13 12.6 5.7 0.56 10.5 0.2 3.5 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Smoa_sbd PF17885.1 OWF55194.1 - 0.021 14.9 6.0 19 5.4 0.1 4.5 2 2 2 5 5 5 0 Styrene monooxygenase A putative substrate binding domain Smoa_sbd PF17885.1 OWF55195.1 - 0.036 14.2 5.5 7.9 6.6 0.2 4.1 1 1 2 3 3 3 0 Styrene monooxygenase A putative substrate binding domain MrpF_PhaF PF04066.13 OWF55195.1 - 0.039 14.4 31.4 14 6.1 0.2 8.5 2 2 6 9 9 9 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF3432 PF11914.8 OWF55196.1 - 0.11 12.8 10.0 0.42 10.9 7.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) DUF3432 PF11914.8 OWF55197.1 - 0.31 11.3 6.7 0.37 11.1 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) DIM PF08194.12 OWF55197.1 - 5.1 7.4 10.3 47 4.3 0.2 4.5 2 1 4 6 6 6 0 DIM protein Linker_histone PF00538.19 OWF55199.1 - 2.6e-25 88.6 1.7 2.6e-25 88.6 1.7 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family Pkinase PF00069.25 OWF55200.1 - 3.8e-51 174.0 0.0 5.3e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55200.1 - 4.9e-23 81.7 0.0 7.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF55200.1 - 0.037 13.9 0.3 0.86 9.5 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OWF55200.1 - 0.11 12.1 1.6 0.27 10.8 0.0 2.2 2 1 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.16 OWF55200.1 - 0.11 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC1 family DUF1744 PF08490.12 OWF55201.1 - 6.1e-147 489.4 0.0 9.6e-147 488.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OWF55201.1 - 9.2e-80 268.3 0.1 1.7e-79 267.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OWF55201.1 - 4.2e-15 55.4 0.9 3.8e-14 52.3 0.9 2.5 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OWF55201.1 - 4.3e-08 33.1 0.1 1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OWF55201.1 - 4e-06 26.9 0.2 2.4e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 RNase_H superfamily MRP-L28 PF09812.9 OWF55202.1 - 7e-22 78.3 7.7 8.4e-22 78.0 7.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 UPF0231 PF06062.11 OWF55202.1 - 0.082 13.2 0.8 0.16 12.2 0.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0231) TPR_10 PF13374.6 OWF55202.1 - 0.096 12.6 0.1 7.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4253 PF14062.6 OWF55202.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4253) YkyA PF10368.9 OWF55202.1 - 0.64 9.7 11.0 0.28 10.8 0.5 2.6 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein CCDC-167 PF15188.6 OWF55202.1 - 2.6 8.5 10.7 22 5.5 9.9 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Fzo_mitofusin PF04799.13 OWF55202.1 - 4.1 6.9 7.5 0.91 9.1 0.8 2.2 1 1 0 2 2 2 0 fzo-like conserved region CC2-LZ PF16516.5 OWF55202.1 - 7.9 6.9 11.5 3.1 8.2 0.6 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Ribosomal_S18 PF01084.20 OWF55203.1 - 1.7e-12 47.4 0.0 3.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 LRR_8 PF13855.6 OWF55204.1 - 6.7e-208 672.7 163.4 8.2e-17 60.7 6.0 21.0 2 2 19 22 22 22 22 Leucine rich repeat LRR_4 PF12799.7 OWF55204.1 - 9.6e-107 346.9 199.2 7.7e-08 32.5 0.7 26.8 14 6 15 30 30 30 30 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF55204.1 - 7.4e-75 249.0 2.3 9.4e-10 38.5 0.0 9.6 2 1 9 11 11 11 11 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF55204.1 - 5.7e-44 149.7 85.0 1.6e-06 27.7 0.4 13.5 1 1 13 14 14 14 14 Leucine-rich repeat LRR_1 PF00560.33 OWF55204.1 - 9.4e-30 98.6 151.4 0.61 10.8 0.3 35.9 31 7 2 33 33 33 14 Leucine Rich Repeat Kelch_6 PF13964.6 OWF55204.1 - 1.3e-06 28.5 0.0 90 3.6 0.0 10.6 9 2 3 12 12 12 0 Kelch motif Kelch_4 PF13418.6 OWF55204.1 - 2e-06 27.7 21.2 42 4.3 0.0 15.8 16 2 2 18 18 18 0 Galactose oxidase, central domain Ycf15 PF10705.9 OWF55204.1 - 0.00017 21.7 15.2 22 5.3 0.0 10.1 7 6 6 14 14 14 0 Chloroplast protein precursor Ycf15 putative TM2 PF05154.16 OWF55204.1 - 0.019 15.3 0.0 19 5.6 0.0 3.8 4 0 0 4 4 4 0 TM2 domain OapA_N PF08525.11 OWF55204.1 - 0.024 14.6 24.9 27 4.8 0.0 8.6 8 0 0 8 8 8 0 Opacity-associated protein A N-terminal motif Kelch_3 PF13415.6 OWF55204.1 - 0.072 13.4 0.0 1e+02 3.4 0.0 6.3 5 1 1 6 6 4 0 Galactose oxidase, central domain HP0268 PF18618.1 OWF55204.1 - 0.2 12.1 0.8 71 3.9 0.1 4.1 4 1 0 4 4 3 0 HP0268 TNFR_c6 PF00020.18 OWF55204.1 - 0.38 11.2 4.2 0.7 10.3 4.2 1.4 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region LRR_8 PF13855.6 OWF55205.1 - 2.2e-82 270.8 80.1 4.4e-14 52.0 6.6 10.1 1 1 8 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 OWF55205.1 - 7.4e-41 137.5 91.9 7.9e-06 26.1 4.8 12.5 4 3 13 17 17 17 16 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF55205.1 - 1.1e-28 99.8 7.8 1.7e-07 31.2 0.7 4.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) 7tm_1 PF00001.21 OWF55205.1 - 2.8e-23 82.6 19.8 4.3e-23 82.0 19.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_9 PF14580.6 OWF55205.1 - 4.9e-20 71.8 49.1 0.00037 20.0 5.1 6.1 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 OWF55205.1 - 2e-12 45.8 68.4 1.7 9.5 0.2 18.0 18 1 0 18 18 18 5 Leucine Rich Repeat 7TM_GPCR_Srw PF10324.9 OWF55205.1 - 0.046 13.0 17.8 1.2 8.3 17.8 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Kelch_4 PF13418.6 OWF55205.1 - 3 7.9 25.3 46 4.1 0.0 10.9 9 5 5 14 14 14 0 Galactose oxidase, central domain SAM_DrpA PF18255.1 OWF55205.1 - 5.4 7.3 6.5 53 4.2 0.1 4.5 4 0 0 4 4 4 0 DNA processing protein A sterile alpha motif domain SERTA PF06031.13 OWF55205.1 - 7.5 6.3 18.8 9 6.1 0.3 5.6 5 0 0 5 5 5 0 SERTA motif Actin PF00022.19 OWF55206.1 - 1.6e-132 442.0 0.0 5.8e-132 440.1 0.0 1.7 1 1 0 1 1 1 1 Actin Pkinase_Tyr PF07714.17 OWF55207.1 - 1.9e-43 148.6 0.2 4.5e-26 91.7 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OWF55207.1 - 1.2e-24 87.1 1.4 2.1e-11 43.7 0.0 3.2 4 0 0 4 4 4 2 Protein kinase domain NAPRTase_N PF17767.1 OWF55207.1 - 0.078 13.4 1.0 42 4.6 0.0 3.4 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Sulfotransfer_1 PF00685.27 OWF55208.1 - 1.6e-13 50.8 0.0 1.6e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Ig_3 PF13927.6 OWF55209.1 - 2.8e-28 98.3 29.7 2.1e-12 47.5 1.5 5.8 5 1 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 OWF55209.1 - 1e-23 83.4 25.2 1.9e-07 31.3 0.5 5.4 5 0 0 5 5 5 5 Immunoglobulin domain C2-set_2 PF08205.12 OWF55209.1 - 4.6e-18 65.1 18.0 1.1e-06 28.6 0.1 4.9 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain ig PF00047.25 OWF55209.1 - 8.9e-18 64.3 28.7 1.9e-06 28.0 0.3 6.3 5 2 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 OWF55209.1 - 1.4e-17 63.5 4.1 3.7e-06 26.9 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin I-set domain V-set PF07686.17 OWF55209.1 - 9.6e-06 25.7 14.8 0.067 13.4 0.2 6.1 5 2 0 5 5 5 2 Immunoglobulin V-set domain C2-set PF05790.15 OWF55209.1 - 0.0073 16.5 4.8 0.31 11.3 0.0 4.5 5 0 0 5 5 5 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 OWF55209.1 - 0.013 15.5 0.1 0.084 12.9 0.0 2.3 2 1 1 3 3 3 0 Izumo-like Immunoglobulin domain PH_RBD PF12068.8 OWF55209.1 - 0.039 13.4 0.1 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Rab-binding domain (RBD) Ig_4 PF16680.5 OWF55209.1 - 0.077 13.3 1.1 6.4 7.1 0.0 4.3 5 0 0 5 5 5 0 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 OWF55209.1 - 0.15 12.5 0.0 0.15 12.5 0.0 4.5 5 2 0 5 5 5 0 Immunoglobulin C1-set domain fn3 PF00041.21 OWF55210.1 - 2.8e-07 30.8 0.1 9.4e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain I-set PF07679.16 OWF55210.1 - 1.6e-05 24.9 0.4 0.0014 18.6 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF55210.1 - 0.00057 20.4 0.2 0.86 10.3 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF55210.1 - 0.022 14.9 0.9 7.9 6.7 0.1 2.7 2 1 0 2 2 2 0 Immunoglobulin V-set domain ig PF00047.25 OWF55210.1 - 0.058 13.6 0.5 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain ITAM PF02189.15 OWF55211.1 - 1.5 9.4 9.8 17 6.1 0.2 4.3 5 0 0 5 5 5 0 Immunoreceptor tyrosine-based activation motif HECT PF00632.25 OWF55213.1 - 6e-09 35.8 0.2 6.8e-08 32.3 0.2 2.2 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) V-set PF07686.17 OWF55213.1 - 0.00024 21.3 0.4 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 OWF55213.1 - 0.022 15.4 5.8 0.21 12.2 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain ig PF00047.25 OWF55213.1 - 0.31 11.2 2.8 0.56 10.4 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin domain Ig_3 PF13927.6 OWF55214.1 - 2.6e-44 149.7 43.5 2.4e-11 44.0 0.4 9.7 9 0 0 9 9 9 6 Immunoglobulin domain Ig_2 PF13895.6 OWF55214.1 - 7.9e-32 109.4 41.1 4e-09 36.7 0.3 9.9 10 1 0 10 10 10 6 Immunoglobulin domain I-set PF07679.16 OWF55214.1 - 7.1e-27 93.3 15.3 6.3e-06 26.2 0.1 9.5 9 3 0 9 9 9 5 Immunoglobulin I-set domain ig PF00047.25 OWF55214.1 - 1e-18 67.3 40.0 8.8e-05 22.6 0.7 9.7 8 3 0 8 8 8 5 Immunoglobulin domain fn3 PF00041.21 OWF55214.1 - 1.2e-15 57.6 1.7 6e-15 55.4 0.6 2.9 3 0 0 3 3 2 1 Fibronectin type III domain C2-set_2 PF08205.12 OWF55214.1 - 6.8e-13 48.5 27.6 1.4e-05 25.1 3.1 6.8 6 1 1 7 7 7 4 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.9 OWF55214.1 - 5.9e-05 23.4 0.0 0.00019 21.8 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2369) Ig_6 PF18452.1 OWF55214.1 - 7.3e-05 22.3 0.0 0.0065 16.0 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 OWF55214.1 - 0.00039 20.5 31.4 0.017 15.3 0.3 8.5 8 2 2 10 10 10 2 Immunoglobulin V-set domain C2-set PF05790.15 OWF55214.1 - 0.00084 19.5 0.4 9.9 6.4 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin C2-set domain Ig_4 PF16680.5 OWF55214.1 - 0.0027 17.9 0.5 2.5 8.4 0.0 4.3 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 OWF55214.1 - 0.012 16.0 19.4 1.7 9.1 0.3 7.7 7 2 1 8 8 8 0 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 OWF55214.1 - 0.024 14.7 0.1 0.5 10.4 0.0 2.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 OWF55214.1 - 0.048 13.7 0.5 1.7 8.6 0.0 3.4 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Sulfotransfer_2 PF03567.14 OWF55215.1 - 8.4e-39 134.0 1.8 2.4e-17 63.7 0.1 3.4 2 1 0 3 3 3 3 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF55215.1 - 0.00015 21.3 3.3 14 5.1 0.0 4.6 3 2 2 5 5 5 2 Sulfotransferase domain YycH PF07435.11 OWF55215.1 - 0.0088 15.1 0.9 1.4 7.8 0.1 2.2 2 0 0 2 2 2 2 YycH protein CSN8_PSD8_EIF3K PF10075.9 OWF55215.1 - 0.013 15.5 0.7 0.53 10.3 0.2 2.5 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Unstab_antitox PF09720.10 OWF55215.1 - 0.019 15.0 1.0 7.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Putative addiction module component GATA PF00320.27 OWF55215.1 - 0.04 13.5 0.7 11 5.7 0.1 2.5 2 0 0 2 2 2 0 GATA zinc finger DUF3512 PF12024.8 OWF55215.1 - 0.088 12.3 0.0 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) Glyco_hydro_65N PF03636.15 OWF55215.1 - 0.13 11.9 0.2 7.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain ATP-synt_ab PF00006.25 OWF55216.1 - 7.2e-109 362.4 0.0 1.1e-108 361.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OWF55216.1 - 2.6e-44 150.0 0.1 5.8e-44 148.8 0.1 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OWF55216.1 - 3.1e-15 56.4 2.5 8.6e-15 55.0 2.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Acetyltransf_1 PF00583.25 OWF55217.1 - 8.7e-14 51.8 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OWF55217.1 - 4.1e-09 36.7 0.1 5.9e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OWF55217.1 - 9.5e-08 32.0 0.1 1.4e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OWF55217.1 - 3.8e-05 23.6 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OWF55217.1 - 7.8e-05 22.9 0.5 0.00012 22.3 0.5 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OWF55217.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OWF55217.1 - 0.0025 17.5 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OWF55217.1 - 0.024 15.3 0.0 0.033 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sulfotransfer_1 PF00685.27 OWF55218.1 - 1.2e-09 38.1 0.6 3e-07 30.2 0.1 2.8 2 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF55218.1 - 7.2e-06 26.5 3.3 1.2e-05 25.9 0.7 2.6 2 1 0 2 2 2 1 Sulfotransferase family YIF1 PF03878.15 OWF55218.1 - 0.21 11.1 1.8 0.34 10.4 1.8 1.3 1 0 0 1 1 1 0 YIF1 MRP-L27 PF09809.9 OWF55219.1 - 2.3e-21 75.7 0.1 3.5e-21 75.2 0.1 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF1108 PF06531.11 OWF55220.1 - 0.017 15.4 10.8 8.9 6.7 0.4 5.0 1 1 3 5 5 5 0 Protein of unknown function (DUF1108) tRNA_synt_2f PF02092.17 OWF55220.1 - 0.032 13.2 7.7 0.39 9.6 0.2 2.2 1 1 0 2 2 2 0 Glycyl-tRNA synthetase beta subunit TUTF7_u4 PF16631.5 OWF55220.1 - 0.09 13.4 25.0 0.045 14.4 7.3 3.0 1 1 2 3 3 3 0 Unstructured region 4 on terminal uridylyltransferase 7 DUF1081 PF06448.11 OWF55220.1 - 0.21 12.0 5.0 2.7 8.4 0.8 2.5 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1081) Membralin PF09746.9 OWF55220.1 - 1.5 7.8 12.3 1.9 7.4 12.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein KH_8 PF17903.1 OWF55220.1 - 8.1 6.6 10.0 3.6 7.8 1.5 3.3 1 1 3 4 4 4 0 Krr1 KH1 domain Phage_sheath_1 PF04984.14 OWF55221.1 - 0.00029 20.7 1.8 0.16 11.8 0.1 2.6 1 1 1 3 3 3 2 Phage tail sheath protein subtilisin-like domain DHNA PF04038.12 OWF55221.1 - 0.23 12.0 2.9 0.64 10.5 0.3 2.1 1 1 0 2 2 2 0 Dihydroneopterin aldolase Spo12 PF05032.12 OWF55221.1 - 1.3 9.0 31.2 10 6.1 0.1 7.3 2 2 5 8 8 8 0 Spo12 family TraI_2B PF18340.1 OWF55221.1 - 5.8 7.1 11.1 5.7 7.1 1.3 3.0 1 1 1 2 2 2 0 DNA relaxase TraI 2B/2B-like domain Phage_sheath_1 PF04984.14 OWF55222.1 - 0.0012 18.7 0.5 2.5 7.9 0.0 3.7 2 2 2 4 4 4 3 Phage tail sheath protein subtilisin-like domain DUF1081 PF06448.11 OWF55222.1 - 0.0038 17.6 7.3 0.071 13.5 0.5 3.0 2 1 1 3 3 3 2 Domain of Unknown Function (DUF1081) Flavi_glycop_C PF02832.16 OWF55222.1 - 0.091 12.9 7.0 19 5.5 0.1 4.5 1 1 4 5 5 5 0 Flavivirus glycoprotein, immunoglobulin-like domain Spo12 PF05032.12 OWF55222.1 - 1.8 8.6 60.8 19 5.2 0.5 12.6 3 3 10 13 13 13 0 Spo12 family Ank_2 PF12796.7 OWF55223.1 - 1.5e-14 54.4 0.0 2.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OWF55223.1 - 1.5e-13 50.5 0.0 8.2e-09 35.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OWF55223.1 - 2.2e-10 40.9 0.0 4.7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55223.1 - 2.8e-10 39.5 0.0 2.5e-05 24.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OWF55223.1 - 1.1e-09 38.4 0.0 1.4e-05 25.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Myb_DNA-bind_7 PF15963.5 OWF55224.1 - 0.012 15.5 5.3 26 4.8 0.1 4.3 1 1 4 5 5 5 0 Myb DNA-binding like CW_7 PF08230.11 OWF55224.1 - 0.26 11.0 1.6 1e+02 2.8 0.1 3.1 3 0 0 3 3 3 0 CW_7 repeat DUF3504 PF12012.8 OWF55225.1 - 4.1 7.3 21.1 12 5.8 0.5 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF3504) CAP PF00188.26 OWF55226.1 - 1.5e-22 80.8 3.5 1.9e-22 80.4 3.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family VCBS PF13517.6 OWF55227.1 - 3.5e-09 37.1 10.7 0.009 16.6 0.4 4.5 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OWF55227.1 - 0.027 14.6 13.6 0.078 13.1 0.1 4.6 5 0 0 5 5 5 0 FG-GAP repeat Bac_rhamnosid_N PF08531.10 OWF55227.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain OB_aCoA_assoc PF01796.17 OWF55227.1 - 0.18 11.8 0.0 2.6 8.1 0.0 2.7 3 0 0 3 3 3 0 DUF35 OB-fold domain, acyl-CoA-associated Glyco_hydro_15 PF00723.21 OWF55228.1 - 9.4e-107 357.6 0.0 1.2e-106 357.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DOR PF14839.6 OWF55229.1 - 7.7e-17 62.1 9.2 2.1e-16 60.7 9.2 1.7 1 1 0 1 1 1 1 DOR family zf-C2H2_3rep PF18868.1 OWF55230.1 - 0.0079 16.9 2.3 0.0079 16.9 2.3 8.0 5 4 2 7 7 7 1 Zinc finger C2H2-type, 3 repeats DUF4187 PF13821.6 OWF55230.1 - 0.012 15.4 3.0 0.11 12.3 1.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) DUF4541 PF15074.6 OWF55231.1 - 1.2e-35 122.0 2.9 1.6e-35 121.6 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Ntox5 PF15543.6 OWF55231.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 5 SPRY PF00622.28 OWF55232.1 - 9.3e-22 77.4 0.2 3.4e-21 75.6 0.1 2.1 2 0 0 2 2 2 1 SPRY domain zf-C3HC4_3 PF13920.6 OWF55232.1 - 5.1e-09 35.9 15.5 1.2e-08 34.6 15.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF55232.1 - 0.021 14.7 15.6 0.054 13.4 15.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HEAT PF02985.22 OWF55233.1 - 1.9e-22 77.4 18.7 0.0071 16.5 0.0 10.7 11 1 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 OWF55233.1 - 6.5e-13 48.9 3.4 0.44 11.0 0.0 7.6 5 3 2 7 7 7 3 HEAT repeats WRNPLPNID PF15017.6 OWF55233.1 - 3.3e-07 31.1 0.1 3.3e-07 31.1 0.1 3.0 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box Cnd1 PF12717.7 OWF55233.1 - 5.6e-05 23.2 9.3 0.2 11.7 0.2 5.5 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OWF55233.1 - 0.0019 18.7 0.9 4.4 8.0 0.1 4.5 2 2 0 2 2 2 1 Vacuolar 14 Fab1-binding region Peptidase_M14 PF00246.24 OWF55234.1 - 1.4e-70 238.4 0.0 1.7e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OWF55234.1 - 1.9e-14 53.8 0.1 3.5e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide PAD_N PF08526.10 OWF55234.1 - 0.12 12.8 0.2 0.97 9.8 0.2 2.2 1 1 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain Peptidase_M14 PF00246.24 OWF55235.1 - 1.3e-73 248.4 0.1 1.5e-73 248.1 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OWF55235.1 - 1.6e-12 47.7 0.2 3.3e-12 46.6 0.2 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF445 PF04286.12 OWF55236.1 - 2e-06 27.9 92.1 0.16 11.7 33.8 3.8 1 1 2 3 3 3 2 Protein of unknown function (DUF445) Spo0A_C PF08769.11 OWF55236.1 - 3.8e-06 26.9 38.7 0.48 10.5 0.6 9.9 1 1 8 10 10 10 5 Sporulation initiation factor Spo0A C terminal RNase_J_C PF17770.1 OWF55236.1 - 0.013 16.5 85.6 8.9 7.4 1.1 16.0 1 1 28 29 29 29 0 Ribonuclease J C-terminal domain Asp-B-Hydro_N PF05279.11 OWF55236.1 - 0.035 14.2 61.1 6.2 6.8 11.9 6.3 1 1 5 6 6 6 0 Aspartyl beta-hydroxylase N-terminal region EcsC PF12787.7 OWF55236.1 - 0.072 12.7 22.4 31 4.1 0.2 8.1 1 1 3 5 5 5 0 EcsC protein family TINF2_N PF14973.6 OWF55236.1 - 1.7 9.0 48.5 1.6 9.1 1.3 10.0 1 1 6 7 7 7 0 TERF1-interacting nuclear factor 2 N-terminus TetR_C_8 PF14278.6 OWF55236.1 - 2.2 8.4 44.1 4.8 7.3 0.4 11.0 2 2 8 13 13 13 0 Transcriptional regulator C-terminal region Condensin2nSMC PF12422.8 OWF55236.1 - 2.2 8.4 15.7 97 3.1 0.0 7.9 1 1 8 10 10 10 0 Condensin II non structural maintenance of chromosomes subunit Sushi PF00084.20 OWF55237.1 - 0.00023 21.7 5.8 7.3 7.3 0.2 5.5 2 2 2 4 4 4 3 Sushi repeat (SCR repeat) DUF948 PF06103.11 OWF55238.1 - 0.81 10.0 4.1 9.7 6.5 0.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DEAD PF00270.29 OWF55239.1 - 9.5e-16 58.1 0.0 2.3e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF55239.1 - 6.5e-15 55.4 0.0 5.7e-12 46.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Drc1-Sld2 PF11719.8 OWF55239.1 - 8.5e-11 42.1 4.2 8.5e-11 42.1 4.2 3.4 3 0 0 3 3 3 1 DNA replication and checkpoint protein zf-CCHC PF00098.23 OWF55239.1 - 3e-06 27.0 3.2 8.1e-06 25.7 3.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OWF55239.1 - 0.041 13.8 0.6 0.12 12.4 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OWF55239.1 - 0.39 10.5 3.9 1.4 8.7 3.9 2.0 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 OWF55239.1 - 0.52 10.2 5.0 1.3 8.9 5.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Na_H_Exchanger PF00999.21 OWF55240.1 - 2.5e-79 266.8 46.7 3.1e-79 266.5 46.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PP2C_C PF07830.13 OWF55240.1 - 0.015 15.8 0.1 2.4 8.7 0.0 2.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Colicin_K PF17500.2 OWF55240.1 - 0.29 11.7 3.8 1.9 9.1 1.9 3.0 2 0 0 2 2 2 0 Colicin-K SNF2_N PF00176.23 OWF55241.1 - 8.1e-62 208.9 0.1 8.1e-62 208.9 0.1 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain BRK PF07533.16 OWF55241.1 - 1.6e-34 117.2 0.1 3.1e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 BRK domain Helicase_C PF00271.31 OWF55241.1 - 1.1e-19 70.8 0.0 3.3e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OWF55241.1 - 6.1e-17 61.3 6.5 2.8e-09 36.8 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain RB_A PF01858.17 OWF55242.1 - 1.2e-76 256.9 1.4 1.4e-74 250.2 0.2 2.5 2 0 0 2 2 2 2 Retinoblastoma-associated protein A domain RB_B PF01857.20 OWF55242.1 - 1.2e-56 190.3 0.4 2e-54 183.2 0.0 3.7 4 0 0 4 4 4 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 OWF55242.1 - 1.8e-47 160.3 1.1 1e-46 157.9 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) Rb_C PF08934.10 OWF55242.1 - 0.023 14.5 0.8 0.061 13.1 0.8 1.7 1 0 0 1 1 1 0 Rb C-terminal domain SNF PF00209.18 OWF55243.1 - 8.2e-183 608.8 40.0 9.7e-183 608.6 40.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Band_7 PF01145.25 OWF55244.1 - 6.5e-22 78.4 0.3 7.9e-22 78.1 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family ITI_HC_C PF06668.12 OWF55245.1 - 0.0047 16.6 55.4 0.28 10.8 7.1 5.7 1 1 5 6 6 6 6 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF365 PF04033.12 OWF55245.1 - 0.02 15.2 17.7 3.1 8.1 1.3 5.4 1 1 6 7 7 7 0 Domain of unknown function (DUF365) Pre-PUA PF17832.1 OWF55245.1 - 0.047 14.4 29.1 1.3e+02 3.3 2.3 8.4 1 1 2 3 3 3 0 Pre-PUA-like domain DUF4318 PF14201.6 OWF55245.1 - 0.16 12.5 16.5 15 6.2 0.2 6.6 1 1 5 6 6 6 0 Domain of unknown function (DUF4318) HutD PF05962.11 OWF55245.1 - 0.22 11.5 2.7 54 3.7 0.1 3.6 1 1 1 4 4 4 0 HutD NTP_transf_9 PF04248.12 OWF55245.1 - 1.5 8.7 31.0 4.4 7.3 2.2 6.3 1 1 6 7 7 7 0 Domain of unknown function (DUF427) DUF4573 PF15140.6 OWF55246.1 - 0.0032 17.3 2.2 0.0063 16.3 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) DUF743 PF05332.11 OWF55246.1 - 1.1 9.3 8.2 19 5.4 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF743) Tcp10_C PF07202.13 OWF55246.1 - 1.5 8.8 15.2 4.9 7.1 1.1 2.2 1 1 1 2 2 2 0 T-complex protein 10 C-terminus TT_ORF1 PF02956.14 OWF55246.1 - 7.9 5.0 12.0 11 4.5 12.0 1.2 1 0 0 1 1 1 0 TT viral orf 1 WAPL PF07814.13 OWF55247.1 - 1.3e-105 353.3 7.1 1.9e-105 352.7 7.1 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 OWF55247.1 - 0.0022 17.3 0.5 0.0052 16.0 0.5 1.6 1 0 0 1 1 1 1 Wap1 domain 7tm_1 PF00001.21 OWF55248.1 - 6.8e-29 101.0 22.1 1e-28 100.4 22.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) bPH_4 PF06713.11 OWF55249.1 - 0.18 11.9 5.6 16 5.7 0.1 4.1 4 2 0 4 4 4 0 Bacterial PH domain Keratin_B2_2 PF13885.6 OWF55250.1 - 9.3e-05 22.3 10.6 0.21 11.6 0.2 4.2 3 1 1 4 4 4 3 Keratin, high sulfur B2 protein ASL_C2 PF14698.6 OWF55250.1 - 0.0013 19.5 12.6 99 3.8 0.0 9.2 3 3 7 10 10 10 0 Argininosuccinate lyase C-terminal PMG PF05287.12 OWF55250.1 - 0.0031 17.6 27.7 0.027 14.5 18.5 2.2 1 1 1 2 2 2 2 PMG protein XPG_N PF00752.17 OWF55250.1 - 0.015 15.8 2.6 8.5 6.9 0.1 3.8 1 1 3 4 4 4 0 XPG N-terminal domain Fox-1_C PF12414.8 OWF55250.1 - 0.29 11.6 11.5 8 6.9 0.5 4.9 1 1 2 4 4 4 0 Calcitonin gene-related peptide regulator C terminal CTD PF12815.7 OWF55250.1 - 0.76 10.4 2.6 44 4.7 2.6 3.1 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Toxin_31 PF08119.11 OWF55250.1 - 4.3 7.1 35.5 6.9 6.5 0.5 7.9 3 3 6 9 9 9 0 Scorpion acidic alpha-KTx toxin family Keratin_B2_2 PF13885.6 OWF55251.1 - 2e-05 24.4 8.8 0.012 15.5 2.1 3.2 1 1 3 4 4 4 4 Keratin, high sulfur B2 protein DUF5419 PF17441.2 OWF55251.1 - 0.0007 19.6 1.4 8.9 6.5 0.4 4.4 1 1 3 4 4 4 1 Family of unknown function (DUF5419) CTD PF12815.7 OWF55251.1 - 0.0014 19.1 2.0 0.69 10.5 0.3 2.4 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 ASL_C2 PF14698.6 OWF55251.1 - 0.0065 17.2 11.4 1.3e+02 3.4 0.1 8.3 1 1 9 10 10 10 0 Argininosuccinate lyase C-terminal PMG PF05287.12 OWF55251.1 - 0.042 13.9 17.7 0.058 13.4 7.3 2.1 1 1 1 2 2 2 0 PMG protein Toxin_31 PF08119.11 OWF55251.1 - 0.13 12.0 26.8 10 6.0 0.1 6.6 1 1 3 5 5 5 0 Scorpion acidic alpha-KTx toxin family Fox-1_C PF12414.8 OWF55251.1 - 0.29 11.6 10.2 15 6.0 0.5 4.2 1 1 3 4 4 4 0 Calcitonin gene-related peptide regulator C terminal MetOD1 PF18546.1 OWF55251.1 - 3.3 7.7 8.5 2.6 8.0 0.1 2.8 1 1 1 3 3 3 0 Metanogen output domain 1 TSP_1 PF00090.19 OWF55251.1 - 4 7.7 21.0 17 5.7 0.4 3.7 1 1 2 3 3 3 0 Thrombospondin type 1 domain HC2 PF07382.11 OWF55251.1 - 4.1 7.4 11.8 8.1 6.5 11.8 1.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 AA_permease_2 PF13520.6 OWF55252.1 - 1.5e-45 155.8 41.8 1.5e-45 155.8 41.8 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 OWF55252.1 - 1.2e-39 136.2 35.8 1.2e-39 136.2 35.8 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 OWF55252.1 - 3.8e-20 71.7 10.1 3.8e-20 71.7 10.1 5.5 8 0 0 8 8 8 1 C-terminus of AA_permease Mad3_BUB1_I PF08311.12 OWF55253.1 - 5.8e-44 149.1 1.5 1.3e-43 147.9 1.5 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 OWF55253.1 - 0.00055 20.1 1.9 0.00089 19.4 0.0 2.0 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Exonuc_VII_L PF02601.15 OWF55253.1 - 0.59 9.6 12.0 1.3 8.5 12.0 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit CTD PF12815.7 OWF55254.1 - 1.3e-11 44.9 4.5 0.2 12.3 0.0 7.2 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Chordopox_A15 PF05846.12 OWF55254.1 - 0.00022 21.4 8.0 16 5.8 0.0 6.6 4 3 2 6 6 6 2 Chordopoxvirus A15 protein HIT PF01230.23 OWF55254.1 - 0.011 16.4 19.1 7.3 7.4 0.1 7.3 4 3 5 9 9 9 0 HIT domain DUF2953 PF11167.8 OWF55254.1 - 2.6 8.2 6.3 1.1e+02 3.0 0.1 6.1 5 2 3 8 8 8 0 Protein of unknown function (DUF2953) Herpes_HEPA PF03324.14 OWF55254.1 - 9 6.8 14.8 15 6.1 0.3 4.6 1 1 2 5 5 5 0 Herpesvirus DNA helicase/primase complex associated protein CTD PF12815.7 OWF55255.1 - 3.2e-18 66.0 7.8 0.0026 18.3 5.6 6.4 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 HIT PF01230.23 OWF55255.1 - 1.9 9.3 19.5 30 5.5 0.3 5.9 4 2 3 7 7 7 0 HIT domain 7tm_1 PF00001.21 OWF55257.1 - 4.3e-78 262.3 2.2 5.6e-78 261.9 2.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF55257.1 - 5.3e-11 42.4 4.3 2.3e-08 33.8 3.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF55257.1 - 4.2e-05 23.3 7.9 9.9e-05 22.1 7.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF55257.1 - 0.016 15.0 3.3 0.23 11.2 3.0 2.3 2 1 0 2 2 2 0 Olfactory receptor Myb_DNA-binding PF00249.31 OWF55258.1 - 1.3e-07 31.6 0.3 3.6e-07 30.3 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OWF55258.1 - 0.0047 16.8 0.6 0.016 15.1 0.6 1.9 1 0 0 1 1 1 1 Myb DNA-binding like VirJ PF06057.11 OWF55258.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) CbeA_antitoxin PF06154.11 OWF55259.1 - 0.0008 20.0 1.2 1.6 9.4 0.0 5.5 1 1 4 7 7 7 1 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Importin_rep_2 PF18786.1 OWF55259.1 - 0.0069 16.2 53.8 1.4 8.9 2.8 8.3 2 2 4 9 9 9 7 Importin 13 repeat CfAFP PF05264.11 OWF55259.1 - 0.026 14.5 0.0 6.7 6.7 0.0 2.8 1 1 3 4 4 4 0 Choristoneura fumiferana antifreeze protein (CfAFP) YlqD PF11068.8 OWF55259.1 - 0.15 12.4 0.0 50 4.3 0.0 3.9 1 1 4 5 5 5 0 YlqD protein PRiA4_ORF3 PF07929.11 OWF55259.1 - 2 8.1 18.6 69 3.1 0.1 5.3 1 1 1 2 2 2 0 Plasmid pRiA4b ORF-3-like protein Sgf11_N PF18519.1 OWF55259.1 - 7.3 6.2 5.9 96 2.7 0.2 4.4 3 1 0 4 4 4 0 SAGA-associated factor 11 N-terminal domain Nse4_C PF08743.10 OWF55260.1 - 1.1e-29 102.5 0.0 3.1e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OWF55260.1 - 6.8e-09 35.7 1.0 2.3e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE DND1_DSRM PF14709.7 OWF55260.1 - 0.042 14.1 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Importin_rep_2 PF18786.1 OWF55260.1 - 0.092 12.6 0.4 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Importin 13 repeat WD40 PF00400.32 OWF55261.1 - 2.3e-11 44.1 4.1 0.23 12.4 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55261.1 - 2.2e-07 31.0 0.1 0.26 11.6 0.0 4.7 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 OWF55261.1 - 0.084 12.4 0.4 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Tyrosine phosphatase family ARL17 PF15840.5 OWF55262.1 - 0.00017 21.9 6.3 31 5.0 0.1 8.6 2 2 9 12 12 12 2 ADP-ribosylation factor-like protein 17 ODAPH PF15848.5 OWF55262.1 - 0.0032 17.9 17.9 16 6.0 0.1 6.3 1 1 5 6 6 6 4 Odontogenesis associated phosphoprotein zf-CHCC PF10276.9 OWF55262.1 - 0.054 13.6 0.1 1e+02 3.1 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger domain RRM_1 PF00076.22 OWF55263.1 - 4.7e-39 132.0 0.1 8e-21 73.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF55263.1 - 3.9e-06 26.9 0.1 0.057 13.5 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OWF55263.1 - 4.6e-05 23.4 0.0 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 OWF55263.1 - 0.00015 21.5 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OWF55263.1 - 0.0033 17.4 0.2 0.4 10.7 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 OWF55263.1 - 0.014 15.7 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF3432 PF11914.8 OWF55264.1 - 5.9e-05 23.2 0.5 4.4 7.6 0.0 4.4 1 1 2 3 3 3 2 Domain of unknown function (DUF3432) DUF4539 PF15072.6 OWF55264.1 - 0.00042 20.3 0.2 2 8.5 0.1 3.9 1 1 3 4 4 4 2 Domain of unknown function (DUF4539) Reo_sigmaC PF04582.12 OWF55264.1 - 0.09 13.0 0.6 67 3.7 0.0 4.0 1 1 2 4 4 4 0 Reovirus sigma C capsid protein C-terminal domain Atthog PF18800.1 OWF55264.1 - 0.13 12.2 4.1 18 5.2 0.1 3.3 2 1 0 3 3 3 0 Attenuator of Hedgehog SPOB_a PF14689.6 OWF55264.1 - 1.4 8.7 9.5 3.2e+02 1.1 0.0 6.1 7 0 0 7 7 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain Tetraspanin PF00335.20 OWF55267.1 - 3.8e-50 170.8 3.9 4.5e-50 170.5 3.9 1.1 1 0 0 1 1 1 1 Tetraspanin family Kinesin PF00225.23 OWF55268.1 - 9e-115 383.1 0.1 9e-115 383.1 0.1 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF55268.1 - 4.4e-26 91.6 0.1 4.4e-26 91.6 0.1 2.6 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 OWF55268.1 - 8.7e-18 65.0 6.5 8.7e-18 65.0 6.5 5.3 2 1 2 5 5 5 1 Kinesin-associated microtubule-binding Scramblase PF03803.15 OWF55269.1 - 0.01 15.1 12.5 1.5 8.0 2.1 4.4 1 1 4 5 5 5 0 Scramblase Ribosomal_L37e PF01907.19 OWF55269.1 - 0.017 15.3 30.4 20 5.5 0.0 13.0 4 4 12 16 16 16 0 Ribosomal protein L37e CsoS2_M PF12288.8 OWF55271.1 - 3.7e-05 23.3 6.2 0.00012 21.7 6.2 1.7 1 1 0 1 1 1 1 Carboxysome shell peptide mid-region Ribosomal_L4 PF00573.22 OWF55271.1 - 4.3 7.0 13.5 4.4e+03 -2.8 13.1 3.1 1 1 0 1 1 1 0 Ribosomal protein L4/L1 family E1-E2_ATPase PF00122.20 OWF55272.1 - 1.7e-54 184.1 1.6 8.7e-53 178.5 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OWF55272.1 - 2.8e-21 76.8 0.2 2.6e-20 73.6 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OWF55272.1 - 5e-21 74.6 0.0 9.5e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OWF55272.1 - 6.7e-20 70.6 0.1 3.1e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 OWF55272.1 - 8.6e-08 32.8 0.0 2.4e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OWF55272.1 - 1.1e-05 25.3 0.2 0.00022 21.1 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Skp1 PF01466.19 OWF55272.1 - 0.13 12.4 0.1 0.42 10.8 0.1 1.9 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DKNYY PF13644.6 OWF55272.1 - 0.18 12.6 0.0 0.51 11.1 0.0 1.7 2 0 0 2 2 2 0 DKNYY family Cation_ATPase_C PF00689.21 OWF55273.1 - 5.5e-45 153.3 3.1 7.1e-45 153.0 3.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus EF-hand_1 PF00036.32 OWF55274.1 - 1e-27 93.5 7.4 6.6e-08 31.6 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OWF55274.1 - 2.1e-24 83.9 4.8 5.3e-05 22.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF55274.1 - 2.3e-24 85.6 1.5 6.6e-11 42.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF55274.1 - 5.4e-20 69.6 7.1 1.9e-06 27.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF55274.1 - 7.3e-20 70.6 2.2 1.3e-12 47.4 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF55274.1 - 6.4e-10 39.3 0.0 0.00025 21.3 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF55274.1 - 1.5e-05 24.9 4.5 0.12 12.4 0.1 3.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF55274.1 - 2.7e-05 24.4 0.1 0.009 16.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 OWF55274.1 - 3.8e-05 23.8 1.5 0.24 11.6 0.1 3.2 2 1 0 2 2 2 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 OWF55274.1 - 0.0087 16.1 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand FG-GAP PF01839.23 OWF55274.1 - 0.069 13.3 6.3 2.1 8.6 0.7 3.2 3 0 0 3 3 3 0 FG-GAP repeat VCBS PF13517.6 OWF55274.1 - 0.099 13.3 4.5 22 5.7 0.0 3.5 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella wnt PF00110.19 OWF55275.1 - 4.4e-117 391.1 23.8 5e-117 390.9 23.8 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 OWF55276.1 - 1.1e-128 429.2 17.5 1.3e-128 429.0 17.5 1.0 1 0 0 1 1 1 1 wnt family DUF963 PF06131.11 OWF55277.1 - 0.00017 21.0 1.7 0.35 10.3 1.6 2.9 2 1 0 2 2 2 2 Schizosaccharomyces pombe repeat of unknown function (DUF963) Bacteriocin_II PF01721.18 OWF55277.1 - 0.031 14.4 7.7 9.3 6.5 0.2 3.7 1 1 2 3 3 3 0 Class II bacteriocin wnt PF00110.19 OWF55278.1 - 1.7e-92 310.3 30.5 2e-92 310.1 30.5 1.0 1 0 0 1 1 1 1 wnt family Ycf15 PF10705.9 OWF55278.1 - 0.054 13.7 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative Laminin_II PF06009.12 OWF55279.1 - 5.7e-06 26.4 20.5 0.00075 19.5 12.8 2.1 1 1 1 2 2 2 2 Laminin Domain II DUF745 PF05335.13 OWF55279.1 - 3.9e-05 23.5 14.5 0.0015 18.3 6.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF745) MCPsignal PF00015.21 OWF55279.1 - 0.00014 21.7 16.7 0.0029 17.4 5.0 2.0 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.11 OWF55279.1 - 0.00063 18.7 30.0 0.00081 18.4 30.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin PF00261.20 OWF55279.1 - 0.00068 19.1 35.8 0.00076 18.9 35.8 1.1 1 0 0 1 1 1 1 Tropomyosin DUF3552 PF12072.8 OWF55279.1 - 0.00099 18.6 34.2 0.14 11.6 11.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) Fib_alpha PF08702.10 OWF55279.1 - 0.0017 18.5 22.5 0.17 12.1 10.9 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family DASH_Duo1 PF08651.10 OWF55279.1 - 0.0022 17.7 17.7 0.19 11.5 1.9 4.0 1 1 4 5 5 5 2 DASH complex subunit Duo1 Cauli_AT PF03233.13 OWF55279.1 - 0.0031 17.4 19.0 0.18 11.7 4.9 2.6 1 1 1 2 2 2 2 Aphid transmission protein TMP_2 PF06791.13 OWF55279.1 - 0.004 16.9 2.5 0.071 12.8 0.3 2.0 1 1 1 2 2 2 1 Prophage tail length tape measure protein COG2 PF06148.11 OWF55279.1 - 0.005 16.9 17.4 0.38 10.8 3.4 3.0 1 1 2 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 E2R135 PF11570.8 OWF55279.1 - 0.0079 16.5 17.4 0.42 10.9 17.4 2.9 1 1 0 1 1 1 1 Coiled-coil receptor-binding R-domain of colicin E2 Laminin_I PF06008.14 OWF55279.1 - 0.0098 15.6 9.1 0.0098 15.6 9.1 2.0 1 1 1 2 2 2 2 Laminin Domain I ApoO PF09769.9 OWF55279.1 - 0.01 15.8 10.3 0.53 10.3 0.6 3.1 1 1 2 3 3 3 0 Apolipoprotein O Exonuc_VII_L PF02601.15 OWF55279.1 - 0.015 14.9 12.4 0.019 14.6 12.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MscS_porin PF12795.7 OWF55279.1 - 0.015 14.9 22.7 0.016 14.8 22.7 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF948 PF06103.11 OWF55279.1 - 0.016 15.5 19.8 1.2e+02 3.1 19.8 3.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 OWF55279.1 - 0.017 13.3 24.4 0.029 12.5 24.3 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Sec8_exocyst PF04048.14 OWF55279.1 - 0.02 14.8 18.1 1 9.2 1.9 3.0 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain BORCS7 PF16088.5 OWF55279.1 - 0.022 15.0 17.3 0.59 10.4 4.4 3.0 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 Glutaredoxin2_C PF04399.13 OWF55279.1 - 0.023 14.5 12.6 2.7 7.8 2.4 3.1 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain DUF1664 PF07889.12 OWF55279.1 - 0.024 14.7 15.5 0.65 10.1 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) L27_N PF09060.10 OWF55279.1 - 0.025 14.6 2.7 12 6.0 0.1 4.4 2 1 2 5 5 5 0 L27_N V-SNARE_C PF12352.8 OWF55279.1 - 0.029 14.7 8.3 0.095 13.0 1.2 3.1 1 1 2 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus WXG100 PF06013.12 OWF55279.1 - 0.036 14.3 11.3 1.5 9.1 0.8 3.5 1 1 4 5 5 5 0 Proteins of 100 residues with WXG IFT57 PF10498.9 OWF55279.1 - 0.042 12.8 24.4 0.099 11.6 24.3 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Dynamitin PF04912.14 OWF55279.1 - 0.044 13.1 25.9 0.32 10.3 6.6 3.0 1 1 2 3 3 3 0 Dynamitin DUF16 PF01519.16 OWF55279.1 - 0.063 13.8 21.4 0.7 10.4 10.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lebercilin PF15619.6 OWF55279.1 - 0.066 12.9 29.3 0.96 9.1 16.5 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CheZ PF04344.13 OWF55279.1 - 0.1 12.5 15.7 0.4 10.6 6.0 2.1 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ DUF4200 PF13863.6 OWF55279.1 - 0.16 12.4 27.3 0.73 10.2 11.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 OWF55279.1 - 0.17 11.1 22.5 0.025 13.8 11.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein Snapin_Pallidin PF14712.6 OWF55279.1 - 0.18 12.2 19.3 7.1 7.1 4.1 3.1 1 1 2 3 3 3 0 Snapin/Pallidin DUF2802 PF10975.8 OWF55279.1 - 0.26 11.4 15.1 17 5.6 0.8 4.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) ATG16 PF08614.11 OWF55279.1 - 0.33 11.2 32.1 21 5.3 16.2 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HemX PF04375.14 OWF55279.1 - 0.34 10.2 18.7 1.7 7.9 9.7 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Uds1 PF15456.6 OWF55279.1 - 0.41 10.8 24.6 2e+02 2.1 24.6 2.5 1 1 0 1 1 1 0 Up-regulated During Septation XhlA PF10779.9 OWF55279.1 - 0.41 10.9 32.0 0.92 9.8 6.9 3.2 1 1 2 3 3 3 0 Haemolysin XhlA FH2 PF02181.23 OWF55279.1 - 0.41 9.7 20.0 0.12 11.5 8.4 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain Tropomyosin_1 PF12718.7 OWF55279.1 - 0.55 10.4 46.0 3.8 7.7 16.6 3.6 1 1 1 2 2 2 0 Tropomyosin like OEP PF02321.18 OWF55279.1 - 0.63 9.8 6.9 0.83 9.4 4.2 1.9 1 1 1 2 2 2 0 Outer membrane efflux protein DLP_helical PF18709.1 OWF55279.1 - 0.68 9.1 18.1 6.4 5.9 9.2 2.4 1 1 1 2 2 2 0 Dynamin-like helical domain RmuC PF02646.16 OWF55279.1 - 0.69 9.0 24.1 1.2 8.2 4.4 2.7 1 1 2 3 3 3 0 RmuC family KELK PF15796.5 OWF55279.1 - 0.72 10.4 26.6 8.7 6.9 13.3 2.8 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase YkyA PF10368.9 OWF55279.1 - 0.86 9.3 34.1 20 4.8 15.4 2.2 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein PIN_8 PF18476.1 OWF55279.1 - 1.4 8.8 18.2 2.1 8.2 18.2 1.4 1 0 0 1 1 1 0 PIN like domain Med9 PF07544.13 OWF55279.1 - 1.5 9.0 16.4 30 4.8 0.7 3.4 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fez1 PF06818.15 OWF55279.1 - 1.7 9.1 31.1 2.9 8.3 12.3 2.0 1 1 1 2 2 2 0 Fez1 Vps53_N PF04100.12 OWF55279.1 - 1.8 7.4 24.4 1.1 8.1 10.1 2.0 1 1 1 2 2 2 0 Vps53-like, N-terminal V_ATPase_I PF01496.19 OWF55279.1 - 2.1 6.1 21.2 2.6 5.9 21.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 OWF55279.1 - 2.4 7.4 17.9 0.66 9.2 13.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 OWF55279.1 - 2.4 6.9 32.2 29 3.3 32.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Prominin PF05478.11 OWF55279.1 - 2.5 5.9 11.3 3.3 5.6 11.3 1.2 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 OWF55279.1 - 3 5.2 24.3 3.3 5.1 24.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tweety PF04906.13 OWF55279.1 - 3.6 6.2 8.3 18 3.8 8.2 1.9 1 1 0 1 1 1 0 Tweety LMBR1 PF04791.16 OWF55279.1 - 4.9 5.9 19.1 7.3 5.4 19.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.11 OWF55279.1 - 5.4 7.1 28.6 24 5.0 28.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 OWF55279.1 - 5.6 7.4 23.3 6.5e+03 -2.4 23.3 2.9 1 1 0 1 1 0 0 Syntaxin-like protein Sulfatase_C PF14707.6 OWF55279.1 - 5.7 7.7 11.7 3.2e+03 -1.2 11.6 2.6 1 1 0 1 1 0 0 C-terminal region of aryl-sulfatase AAA_13 PF13166.6 OWF55279.1 - 9.9 4.7 23.1 3.3 6.3 8.9 1.8 1 1 1 2 2 2 0 AAA domain TMF_DNA_bd PF12329.8 OWF55279.1 - 10 6.2 39.4 12 6.0 10.6 3.5 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding Dynamitin PF04912.14 OWF55280.1 - 0.003 17.0 10.7 0.003 17.0 10.7 1.0 1 0 0 1 1 1 1 Dynamitin Laminin_II PF06009.12 OWF55280.1 - 0.067 13.2 6.6 0.072 13.1 6.6 1.0 1 0 0 1 1 1 0 Laminin Domain II Syntaxin_2 PF14523.6 OWF55280.1 - 0.074 13.4 5.8 0.087 13.2 5.8 1.2 1 0 0 1 1 1 0 Syntaxin-like protein DUF948 PF06103.11 OWF55280.1 - 0.075 13.3 3.3 0.094 13.0 3.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3886 PF13025.6 OWF55280.1 - 0.12 12.6 19.5 0.52 10.5 6.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) Cauli_AT PF03233.13 OWF55280.1 - 0.14 12.1 5.4 0.15 11.9 5.4 1.1 1 0 0 1 1 1 0 Aphid transmission protein Fib_alpha PF08702.10 OWF55280.1 - 0.16 12.1 8.0 0.17 12.1 8.0 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 OWF55280.1 - 0.19 11.4 6.5 0.21 11.3 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF883 PF05957.13 OWF55280.1 - 0.19 12.3 7.5 0.2 12.3 7.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RmuC PF02646.16 OWF55280.1 - 0.51 9.4 12.3 0.55 9.3 12.3 1.0 1 0 0 1 1 1 0 RmuC family DUF812 PF05667.11 OWF55280.1 - 0.59 8.9 15.7 0.67 8.8 15.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ApoO PF09769.9 OWF55280.1 - 0.6 10.1 3.5 0.65 10.0 3.5 1.2 1 0 0 1 1 1 0 Apolipoprotein O XhlA PF10779.9 OWF55280.1 - 0.62 10.3 9.1 0.72 10.1 9.1 1.2 1 0 0 1 1 1 0 Haemolysin XhlA UPF0242 PF06785.11 OWF55280.1 - 0.7 10.0 13.5 0.72 9.9 13.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3552 PF12072.8 OWF55280.1 - 0.88 9.0 15.4 0.91 8.9 15.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 OWF55280.1 - 0.91 8.3 14.3 0.92 8.3 14.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DLP_helical PF18709.1 OWF55280.1 - 1.3 8.1 8.7 1.3 8.2 8.7 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain PikAIV_N PF18605.1 OWF55280.1 - 1.8 8.2 19.4 27 4.5 0.2 5.4 2 2 3 5 5 5 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HSP70 PF00012.20 OWF55280.1 - 2 6.5 12.5 1.9 6.5 12.5 1.0 1 0 0 1 1 1 0 Hsp70 protein TMPIT PF07851.13 OWF55280.1 - 2.4 7.3 10.1 2.4 7.3 10.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein Halogen_Hydrol PF10112.9 OWF55280.1 - 2.5 8.1 9.8 15 5.6 9.8 1.9 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein eIF3_N PF09440.10 OWF55280.1 - 3.2 8.2 9.6 3.3 8.1 9.6 1.0 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF4199 PF13858.6 OWF55280.1 - 8 6.8 6.2 8.9 6.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) zf-C3HC4_3 PF13920.6 OWF55281.1 - 1.6e-11 43.8 5.9 2.7e-11 43.1 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OWF55281.1 - 8.3e-11 41.6 9.7 1.5e-10 40.8 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF55281.1 - 8.4e-11 42.0 8.1 1.5e-10 41.2 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OWF55281.1 - 6.8e-10 38.7 8.0 1.1e-09 38.0 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF55281.1 - 2.6e-09 36.9 5.8 5.2e-09 36.0 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OWF55281.1 - 2.1e-08 34.0 5.5 3.7e-08 33.2 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OWF55281.1 - 1.5e-07 31.2 7.6 5.5e-07 29.3 8.0 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF55281.1 - 3.9e-07 30.3 4.8 8e-07 29.3 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OWF55281.1 - 1.2e-06 28.5 8.8 2.6e-06 27.5 8.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OWF55281.1 - 0.00018 21.5 2.9 0.00038 20.4 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OWF55281.1 - 0.00079 19.3 3.9 0.0017 18.2 3.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TerY_C PF15616.6 OWF55281.1 - 0.0013 18.8 1.5 0.0023 18.0 1.5 1.3 1 0 0 1 1 1 1 TerY-C metal binding domain Protocadherin PF08374.11 OWF55281.1 - 0.0037 17.3 0.3 0.0061 16.6 0.3 1.2 1 0 0 1 1 1 1 Protocadherin zf-RING_4 PF14570.6 OWF55281.1 - 0.073 12.9 7.4 0.52 10.1 3.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OWF55281.1 - 0.089 12.4 5.4 0.21 11.2 5.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OWF55281.1 - 0.13 12.1 2.7 0.24 11.3 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.12 OWF55281.1 - 0.18 11.8 5.5 0.29 11.1 5.5 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 OWF55281.1 - 0.45 10.7 3.2 1 9.5 3.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 OWF55281.1 - 0.92 9.6 4.6 1.8 8.6 4.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn-C2H2_12 PF18112.1 OWF55281.1 - 8.2 7.0 9.0 12 6.5 0.2 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain GIT1_C PF12205.8 OWF55282.1 - 1.2e-39 135.0 0.1 1.2e-39 135.0 0.1 2.9 3 1 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term ArfGap PF01412.18 OWF55282.1 - 1.1e-30 106.1 0.5 3.9e-30 104.3 0.5 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.11 OWF55282.1 - 2.3e-26 91.1 1.1 4.3e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Ank_2 PF12796.7 OWF55282.1 - 1.3e-08 35.3 0.0 3.9e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) GIT_CC PF16559.5 OWF55282.1 - 1.2e-07 31.5 0.2 3.9e-07 29.8 0.2 1.9 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Ank_4 PF13637.6 OWF55282.1 - 1.1e-06 29.0 0.1 0.0004 20.9 0.0 3.3 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55282.1 - 5e-05 23.4 0.0 3.2 8.6 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OWF55282.1 - 0.0029 17.9 0.0 0.0082 16.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OWF55282.1 - 0.014 15.8 0.1 14 6.4 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat TTRAP PF14203.6 OWF55282.1 - 0.03 14.3 0.0 0.099 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Scaffolding_pro PF11418.8 OWF55282.1 - 0.052 14.1 0.6 0.99 10.0 0.1 2.8 3 0 0 3 3 3 0 Phi29 scaffolding protein DivIC PF04977.15 OWF55282.1 - 0.21 11.4 1.8 0.45 10.3 0.4 2.4 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 OWF55282.1 - 0.23 11.6 1.6 0.79 9.9 1.6 2.0 1 0 0 1 1 1 0 bZIP transcription factor DUF2052 PF09747.9 OWF55282.1 - 1.9 8.6 6.6 0.65 10.1 2.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Seryl_tRNA_N PF02403.22 OWF55282.1 - 3.6 7.9 6.5 1.2 9.4 0.3 2.8 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain GPCR_chapero_1 PF11904.8 OWF55283.1 - 6.1e-103 344.5 0.8 7e-103 344.3 0.1 1.4 2 0 0 2 2 2 1 GPCR-chaperone Ank_2 PF12796.7 OWF55283.1 - 1.1e-08 35.5 0.0 3.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF55283.1 - 2.2e-06 27.8 0.0 9.2e-05 22.7 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF55283.1 - 6.9e-06 26.3 0.2 0.001 19.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 OWF55283.1 - 1.5e-05 25.0 0.0 0.28 11.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OWF55283.1 - 7.4e-05 23.2 0.0 0.00019 22.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RAP80_UIM PF18282.1 OWF55283.1 - 0.24 11.2 6.7 1.2 9.0 0.0 3.4 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif EIF4E-T PF10477.9 OWF55284.1 - 3.4e-49 168.3 87.1 3.4e-49 168.3 87.1 5.5 1 1 2 3 3 3 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E MMR_HSR1_Xtn PF16897.5 OWF55285.1 - 1.2e-40 137.8 1.0 2.1e-40 137.0 1.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OWF55285.1 - 9.7e-23 80.0 0.0 1.8e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OWF55285.1 - 3e-19 69.2 0.1 1.4e-18 67.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OWF55285.1 - 1.2e-10 41.1 0.2 1.8e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OWF55285.1 - 0.0048 16.5 0.0 2.1 7.8 0.0 3.4 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OWF55285.1 - 0.0068 15.4 0.1 0.024 13.6 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OWF55285.1 - 0.013 15.5 1.2 3 7.9 0.2 2.7 2 1 1 3 3 3 0 Dynamin family DUF5388 PF17363.2 OWF55286.1 - 0.035 14.3 0.0 0.25 11.6 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5388) Ribosomal_S13_N PF08069.12 OWF55286.1 - 0.093 12.8 0.4 0.42 10.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain VPS9 PF02204.18 OWF55289.1 - 5.5e-31 106.9 0.1 1.8e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OWF55289.1 - 1.9e-21 76.1 0.1 1e-20 73.8 0.1 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 OWF55289.1 - 2.7e-13 49.6 9.1 5.5e-13 48.6 9.1 1.6 1 0 0 1 1 1 1 A20-like zinc finger DUF1439 PF07273.12 OWF55289.1 - 0.017 14.9 0.4 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1439) Ndc1_Nup PF09531.10 OWF55289.1 - 0.017 13.8 0.8 0.031 13.0 0.8 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FANCI_S2 PF14676.6 OWF55289.1 - 0.052 13.9 0.1 5.7 7.2 0.0 2.5 2 0 0 2 2 2 0 FANCI solenoid 2 DUF2935 PF11155.8 OWF55289.1 - 0.072 13.4 3.1 5 7.5 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) FpoO PF10621.9 OWF55289.1 - 0.072 13.4 0.6 0.3 11.4 0.2 2.3 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF4047 PF13256.6 OWF55289.1 - 0.13 12.5 6.7 1.3 9.2 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) COG6 PF06419.11 OWF55289.1 - 0.28 9.4 5.7 0.045 12.0 1.1 1.8 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 AcylCoA_dehyd_C PF12186.8 OWF55289.1 - 0.59 10.3 2.7 31 4.7 0.0 3.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal TCTP PF00838.17 OWF55289.1 - 0.7 10.2 5.5 0.21 11.9 1.8 1.9 2 0 0 2 2 2 0 Translationally controlled tumour protein DUF148 PF02520.17 OWF55289.1 - 3.7 7.7 12.8 10 6.3 0.3 4.0 3 1 1 4 4 4 0 Domain of unknown function DUF148 Ribonucleas_3_3 PF14622.6 OWF55290.1 - 0.00097 19.3 0.0 0.0027 17.8 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OWF55290.1 - 0.075 13.7 0.0 0.33 11.6 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease III domain MRP-63 PF14978.6 OWF55291.1 - 1.2e-16 61.1 4.0 1.7e-16 60.6 4.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 Guanylate_cyc_2 PF09778.9 OWF55292.1 - 3.5e-46 157.2 4.0 4.6e-46 156.9 4.0 1.1 1 0 0 1 1 1 1 Guanylylate cyclase DUF3335 PF11814.8 OWF55292.1 - 0.0058 16.1 0.1 2.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.15 OWF55292.1 - 0.048 13.5 0.5 0.13 12.1 0.5 1.8 1 1 0 1 1 1 0 Peptidase C39 family Peptidase_C70 PF12385.8 OWF55292.1 - 0.08 12.9 0.6 0.16 12.0 0.6 1.7 1 1 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 eRF1_1 PF03463.15 OWF55293.1 - 8.4e-49 164.9 0.2 1.7e-48 163.9 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 OWF55293.1 - 2.7e-33 115.1 0.1 4.9e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OWF55293.1 - 1.7e-25 89.7 0.1 3.5e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 ATPase_2 PF01637.18 OWF55293.1 - 0.064 13.2 0.5 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea LRR_6 PF13516.6 OWF55294.1 - 0.0018 18.2 6.8 6.2 7.1 0.3 4.2 3 0 0 3 3 3 3 Leucine Rich repeat LRR_8 PF13855.6 OWF55294.1 - 0.0095 15.7 15.5 0.27 11.0 0.6 4.9 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 OWF55294.1 - 0.36 11.3 18.7 2.8 8.5 4.1 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF55294.1 - 7.6 7.5 14.8 48 5.1 0.3 5.1 3 1 0 3 3 3 0 Leucine Rich Repeat KH_1 PF00013.29 OWF55295.1 - 1.1e-10 41.2 0.0 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 OWF55295.1 - 0.003 17.4 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 KH domain TUDOR PF00567.24 OWF55295.1 - 0.0082 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Pkinase PF00069.25 OWF55296.1 - 2.2e-65 220.6 0.0 3.5e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55296.1 - 3e-48 164.4 0.0 4.8e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 OWF55296.1 - 2.3e-22 79.6 2.3 4.2e-22 78.8 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 OWF55296.1 - 2.8e-07 30.1 0.0 6.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF55296.1 - 1.8e-05 24.8 0.1 0.12 12.3 0.0 3.2 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF55296.1 - 0.00011 21.7 0.0 0.00036 19.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OWF55296.1 - 0.00012 21.7 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OWF55296.1 - 0.00021 20.2 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase MIT PF04212.18 OWF55296.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Spore_III_AB PF09548.10 OWF55296.1 - 3.9 7.6 5.3 6 6.9 3.2 2.2 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Fringe PF02434.16 OWF55297.1 - 6.1e-64 215.9 0.0 1.4e-50 172.1 0.0 2.9 3 0 0 3 3 3 2 Fringe-like DUF3055 PF11256.8 OWF55300.1 - 0.26 11.6 40.7 16 5.8 0.1 12.1 1 1 11 14 14 14 0 Protein of unknown function (DUF3055) Exo5 PF09810.9 OWF55301.1 - 1.7e-58 198.9 4.8 2.7e-24 86.3 0.0 3.4 1 1 2 3 3 3 3 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 OWF55301.1 - 6.5e-08 32.8 0.2 1.2e-07 31.9 0.0 1.5 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Galactosyl_T PF01762.21 OWF55303.1 - 3.2e-18 66.2 0.6 4e-18 65.9 0.6 1.0 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF55303.1 - 0.018 14.4 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Glycos_transf_2 PF00535.26 OWF55303.1 - 0.029 14.2 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Galactosyl_T PF01762.21 OWF55304.1 - 1.2e-42 146.0 1.5 2.6e-42 144.9 1.5 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF55304.1 - 0.0013 18.2 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Fringe-like Glycos_transf_2 PF00535.26 OWF55304.1 - 0.0028 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Neur_chan_LBD PF02931.23 OWF55305.1 - 1.2e-66 224.2 2.3 1.7e-66 223.8 2.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF55305.1 - 3.6e-38 132.0 0.1 5.1e-38 131.5 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF55306.1 - 1.7e-67 227.0 1.6 2.6e-67 226.4 1.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF55306.1 - 1.5e-40 139.8 0.0 2.2e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3681 PF12442.8 OWF55306.1 - 0.049 14.1 0.7 0.12 12.9 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) Ig_3 PF13927.6 OWF55307.1 - 1e-06 29.2 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF55307.1 - 6e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF55307.1 - 0.00049 20.4 0.0 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 OWF55307.1 - 0.002 18.5 0.0 0.0052 17.2 0.0 1.6 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain CEND1 PF15677.5 OWF55307.1 - 0.0026 18.3 0.0 0.0036 17.9 0.0 1.1 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 V-set PF07686.17 OWF55307.1 - 0.0055 16.9 0.5 0.048 13.8 0.1 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 OWF55307.1 - 0.015 15.4 0.0 0.054 13.7 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Ig_6 PF18452.1 OWF55307.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 OWF55308.1 - 2.7e-107 351.0 0.4 1.7e-14 53.6 0.0 10.2 9 2 0 9 9 9 9 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF55308.1 - 1.2e-101 333.4 12.2 4.8e-14 52.7 0.1 9.5 9 0 0 9 9 9 9 Immunoglobulin domain ig PF00047.25 OWF55308.1 - 9.8e-73 240.4 13.8 1.7e-10 41.0 0.1 9.7 9 1 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.6 OWF55308.1 - 8.1e-62 205.5 5.6 1.5e-09 38.0 0.0 9.5 9 1 0 9 9 9 8 Immunoglobulin domain V-set PF07686.17 OWF55308.1 - 3.1e-43 146.4 12.7 1.5e-07 31.5 0.0 13.1 8 5 1 10 10 10 8 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF55308.1 - 1.9e-17 63.1 7.9 0.046 13.8 0.0 7.0 6 1 1 7 7 7 5 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 OWF55308.1 - 3.8e-12 45.6 0.1 0.24 11.0 0.0 6.4 6 0 0 6 6 6 3 Immunoglobulin domain Ig_5 PF16681.5 OWF55308.1 - 1.9e-11 44.2 0.0 0.27 11.6 0.0 8.2 9 2 0 9 9 8 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 OWF55308.1 - 1.9e-10 40.6 0.0 3.9 7.6 0.0 6.8 7 0 0 7 7 7 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 OWF55308.1 - 3.9e-09 36.7 0.0 0.23 11.8 0.0 6.9 8 1 0 8 8 8 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 OWF55308.1 - 0.00099 19.1 0.1 9.6 6.3 0.0 5.0 5 0 0 5 5 5 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 OWF55308.1 - 0.0075 16.5 0.1 4.9 7.4 0.0 4.1 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 OWF55308.1 - 0.12 12.3 0.5 23 5.0 0.0 4.0 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain COesterase PF00135.28 OWF55309.1 - 4.1e-115 385.6 0.0 5.9e-115 385.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF55309.1 - 8.3e-05 22.5 0.4 0.00077 19.4 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold CDC48_2 PF02933.17 OWF55309.1 - 0.17 11.7 0.0 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 XPA_C PF05181.12 OWF55310.1 - 1.3e-22 79.5 0.1 3e-22 78.3 0.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 OWF55310.1 - 1.4e-11 44.2 5.8 1.4e-11 44.2 5.8 1.7 2 0 0 2 2 2 1 XPA protein N-terminal zf-CpG_bind_C PF12269.8 OWF55310.1 - 9.1e-05 22.4 1.6 9.1e-05 22.4 1.6 1.5 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain TipAS PF07739.13 OWF55310.1 - 0.0028 18.2 1.3 0.0028 18.2 1.3 1.6 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain SRCR PF00530.18 OWF55311.1 - 6.9e-100 328.1 30.0 3.9e-26 91.5 2.9 6.1 6 0 0 6 6 6 6 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 OWF55311.1 - 2.9e-24 85.5 20.8 0.0001 22.7 0.5 6.7 6 1 0 6 6 6 6 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 OWF55311.1 - 7.2e-14 52.2 2.3 0.31 11.6 0.0 6.7 5 1 2 7 7 7 5 Hepsin, SRCR domain Arena_nucleocap PF00843.17 OWF55311.1 - 0.23 10.3 0.0 0.47 9.3 0.0 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain Ribosomal_S16 PF00886.19 OWF55315.1 - 1.5e-16 60.2 0.0 2.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 DUF829 PF05705.14 OWF55316.1 - 6.5e-32 111.3 0.2 8.5e-32 111.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Kdo PF06293.14 OWF55316.1 - 0.06 12.7 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 7tm_1 PF00001.21 OWF55317.1 - 2.1e-44 151.9 18.6 2.9e-44 151.4 18.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF55317.1 - 4.7e-09 36.0 19.4 6.3e-09 35.6 19.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF55317.1 - 7.1e-06 25.8 15.1 7.1e-06 25.8 15.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 OWF55317.1 - 0.045 13.0 24.6 0.83 8.9 24.6 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw TMEM40 PF15817.5 OWF55317.1 - 0.38 10.5 2.5 1.3 8.8 0.1 2.8 1 1 2 3 3 3 0 Transmembrane protein 40 family Ank_2 PF12796.7 OWF55318.1 - 1.5e-50 169.7 4.8 3.9e-17 62.6 0.1 5.8 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF55318.1 - 5.1e-33 112.7 6.0 1.7e-07 31.3 0.1 8.4 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55318.1 - 2.1e-32 107.5 8.4 0.0002 21.6 0.0 10.1 8 1 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 OWF55318.1 - 9.1e-32 108.1 10.9 0.00048 20.4 0.0 8.9 7 1 1 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 OWF55318.1 - 1.7e-30 105.0 1.2 1.6e-10 41.3 0.0 7.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) TPR_10 PF13374.6 OWF55318.1 - 0.065 13.1 0.6 0.56 10.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 OWF55319.1 - 4.4e-142 462.6 54.7 3.4e-14 53.2 0.7 14.6 14 0 0 14 14 14 14 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF55319.1 - 1.8e-61 202.9 94.7 3.5e-10 39.4 1.4 15.8 16 0 0 16 16 16 10 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 OWF55319.1 - 1.2e-59 202.3 0.0 2.5e-59 201.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 OWF55319.1 - 7.3e-17 61.6 0.1 2e-16 60.2 0.1 1.7 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.32 OWF55319.1 - 5e-16 58.8 18.8 0.00035 21.3 0.2 8.1 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55319.1 - 2.5e-07 30.9 2.7 0.57 10.5 0.0 5.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DTW PF03942.15 OWF55321.1 - 7e-29 101.0 0.0 9.6e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 DTW domain NUDIX-like PF09296.11 OWF55322.1 - 1.6e-14 54.4 0.0 4.2e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 OWF55322.1 - 3.8e-14 52.8 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain Ank_4 PF13637.6 OWF55322.1 - 1.6e-12 47.7 0.2 1.5e-07 31.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF55322.1 - 3.3e-11 43.6 0.3 1e-10 42.0 0.3 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF55322.1 - 1.3e-08 34.9 0.2 4.9e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.11 OWF55322.1 - 4.3e-08 32.7 1.6 1.1e-07 31.4 1.6 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_3 PF13606.6 OWF55322.1 - 4.5e-08 32.7 0.1 1.1e-06 28.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OWF55322.1 - 7.9e-08 32.4 0.1 3.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat SH3_17 PF18350.1 OWF55323.1 - 7.1e-06 25.8 11.6 0.88 9.5 0.3 4.8 1 1 4 6 6 6 5 Restriction endonuclease SH3 domain HEAT_UF PF18817.1 OWF55323.1 - 0.00035 20.8 1.4 16 5.8 0.0 5.7 2 1 4 6 6 6 1 Repeat of uncharacterized protein PH0542 Cas9_C PF18525.1 OWF55323.1 - 0.045 14.0 6.5 28 4.9 2.1 4.1 1 1 2 3 3 3 0 Cas9 C-terminal domain Colicin_M PF14859.6 OWF55323.1 - 0.081 12.0 0.8 2 7.5 0.1 2.4 1 1 1 2 2 2 0 Colicin M DUF2737 PF10930.8 OWF55323.1 - 0.086 12.4 12.2 33 4.2 0.1 5.9 1 1 5 6 6 6 0 Protein of unknown function (DUF2737) Ribosomal_L28e PF01778.17 OWF55323.1 - 0.25 12.1 1.6 10 6.9 0.1 2.8 1 1 1 2 2 2 0 Ribosomal L28e protein family LAM_C PF12544.8 OWF55323.1 - 0.92 9.7 2.7 37 4.5 0.1 3.3 1 1 2 4 4 4 0 Lysine-2,3-aminomutase AMP-binding PF00501.28 OWF55324.1 - 8.5e-56 189.3 0.0 1.1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF55324.1 - 0.00018 22.4 0.0 0.00042 21.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YwiC PF14256.6 OWF55324.1 - 0.13 12.6 0.2 0.26 11.6 0.2 1.4 1 0 0 1 1 1 0 YwiC-like protein HSP70 PF00012.20 OWF55325.1 - 9.5e-10 37.3 0.0 1.6e-08 33.2 0.0 2.5 1 1 0 1 1 1 1 Hsp70 protein DDR PF08841.10 OWF55325.1 - 0.063 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain GalKase_gal_bdg PF10509.9 OWF55326.1 - 1.7e-22 78.7 0.2 3.2e-22 77.8 0.2 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 OWF55326.1 - 3.4e-12 46.6 0.1 1.4e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OWF55326.1 - 4.8e-09 36.3 0.3 1e-08 35.3 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain BPS PF08947.10 OWF55326.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 BPS (Between PH and SH2) AAA PF00004.29 OWF55328.1 - 1.1e-37 129.4 0.0 2.5e-37 128.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OWF55328.1 - 4.2e-14 52.3 0.1 1.1e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 OWF55328.1 - 3.6e-07 30.4 0.0 9.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OWF55328.1 - 6.2e-07 30.0 0.5 5e-05 23.8 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OWF55328.1 - 2.9e-06 27.1 0.0 7.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OWF55328.1 - 3.1e-06 27.2 0.0 9.7e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OWF55328.1 - 2.4e-05 23.7 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 OWF55328.1 - 3.1e-05 24.3 1.0 0.014 15.7 0.3 2.9 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OWF55328.1 - 3.3e-05 24.2 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 RNA helicase AAA_lid_3 PF17862.1 OWF55328.1 - 4e-05 23.3 0.0 0.00018 21.3 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain NACHT PF05729.12 OWF55328.1 - 6.9e-05 22.8 0.0 0.099 12.6 0.0 2.4 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 OWF55328.1 - 0.00025 21.6 0.0 0.00078 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OWF55328.1 - 0.0014 18.6 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OWF55328.1 - 0.0016 18.2 0.0 0.0047 16.7 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 OWF55328.1 - 0.002 17.8 0.0 0.0061 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 OWF55328.1 - 0.0045 16.1 0.0 0.046 12.8 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OWF55328.1 - 0.0077 15.4 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OWF55328.1 - 0.0079 15.5 0.1 1.8 7.7 0.0 2.5 2 1 1 3 3 3 1 KAP family P-loop domain AAA_25 PF13481.6 OWF55328.1 - 0.0081 15.8 0.0 0.28 10.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 OWF55328.1 - 0.012 16.0 0.0 0.039 14.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 OWF55328.1 - 0.013 14.9 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 KaiC MCM PF00493.23 OWF55328.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 OWF55328.1 - 0.014 14.8 0.1 0.056 12.8 0.0 2.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OWF55328.1 - 0.015 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OWF55328.1 - 0.019 14.5 0.0 0.059 12.9 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OWF55328.1 - 0.02 15.0 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OWF55328.1 - 0.029 14.9 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 OWF55328.1 - 0.045 13.5 0.0 0.39 10.4 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 OWF55328.1 - 0.05 13.5 0.2 1.3 8.8 0.2 2.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 OWF55328.1 - 0.098 12.7 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 OWF55328.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 OWF55328.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain SPK PF04435.18 OWF55328.1 - 0.16 12.4 1.1 0.49 10.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF545) DUF2963 PF11178.8 OWF55329.1 - 5.2e-05 22.9 7.6 4.6 7.0 0.7 5.8 1 1 2 3 3 3 3 Protein of unknown function (DUF2963) MgtE_N PF03448.17 OWF55329.1 - 7.6e-05 23.3 0.0 0.00024 21.6 0.0 1.5 1 1 0 1 1 1 1 MgtE intracellular N domain TSP9 PF11493.8 OWF55329.1 - 0.037 14.7 3.6 16 6.3 0.1 3.7 1 1 1 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 HEV_ORF1 PF02444.16 OWF55329.1 - 1.9 9.1 3.8 14 6.3 0.5 2.6 1 1 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) MgtE_N PF03448.17 OWF55330.1 - 4.2e-15 56.2 0.0 3.3e-05 24.4 0.0 3.9 1 1 2 4 4 4 4 MgtE intracellular N domain Speriolin_N PF15058.6 OWF55330.1 - 3.7e-06 27.2 1.6 0.061 13.4 0.4 3.2 1 1 2 3 3 3 3 Speriolin N terminus DUF2963 PF11178.8 OWF55330.1 - 0.002 17.8 26.7 4.1 7.2 0.3 9.9 1 1 7 9 9 9 5 Protein of unknown function (DUF2963) HEV_ORF1 PF02444.16 OWF55330.1 - 8.3 7.0 12.6 12 6.5 0.8 4.7 1 1 3 5 5 5 0 Hepatitis E virus ORF-2 (Putative capsid protein) A_deamin PF02137.18 OWF55331.1 - 3.7e-78 263.3 0.0 6.1e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 OWF55331.1 - 2.4e-22 79.4 0.5 2.5e-11 44.1 0.1 3.2 3 0 0 3 3 3 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 OWF55331.1 - 0.052 13.8 1.3 3.9 7.8 0.2 3.7 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF2518 PF10726.9 OWF55331.1 - 0.22 11.2 0.0 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) ubiquitin PF00240.23 OWF55332.1 - 1.2e-07 31.4 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OWF55332.1 - 3.2e-05 23.7 0.3 5.1e-05 23.0 0.3 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OWF55332.1 - 0.14 12.6 0.4 0.67 10.5 0.4 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain TPR_12 PF13424.6 OWF55333.1 - 5.6e-115 375.8 93.2 5.1e-13 49.1 0.8 16.6 14 3 3 17 17 17 14 Tetratricopeptide repeat TPR_7 PF13176.6 OWF55333.1 - 1.2e-93 300.4 64.1 0.00026 20.8 0.0 24.8 25 0 0 25 25 25 22 Tetratricopeptide repeat TPR_1 PF00515.28 OWF55333.1 - 4.2e-85 276.4 79.8 5.8e-05 22.7 0.5 26.0 26 0 0 26 26 26 21 Tetratricopeptide repeat CHAT PF12770.7 OWF55333.1 - 8.2e-64 215.8 0.2 1.4e-63 215.0 0.2 1.4 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 OWF55333.1 - 1.2e-61 199.8 74.1 0.00036 20.5 0.2 26.9 27 0 0 27 27 27 14 Tetratricopeptide repeat TPR_2 PF07719.17 OWF55333.1 - 2.6e-54 177.0 83.1 0.0013 18.7 0.8 26.6 28 0 0 28 28 28 15 Tetratricopeptide repeat TPR_10 PF13374.6 OWF55333.1 - 2.2e-43 144.9 68.6 0.00034 20.4 0.2 24.3 27 1 1 28 28 27 11 Tetratricopeptide repeat TPR_MalT PF17874.1 OWF55333.1 - 1.3e-18 67.5 50.6 6.7e-06 25.7 3.9 8.3 3 2 4 7 7 7 6 MalT-like TPR region Rapsyn_N PF10579.9 OWF55333.1 - 4e-18 65.3 22.4 0.015 15.4 0.0 12.4 8 4 4 13 13 13 5 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 OWF55333.1 - 2.9e-17 61.9 36.8 0.4 11.6 0.3 19.5 20 4 4 24 24 20 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF55333.1 - 9.8e-14 50.8 35.1 0.00041 20.0 0.1 17.6 18 3 3 21 21 20 2 TPR repeat TPR_16 PF13432.6 OWF55333.1 - 3e-11 43.8 42.0 0.005 17.4 0.1 16.0 11 6 4 16 16 16 2 Tetratricopeptide repeat RPN7 PF10602.9 OWF55333.1 - 5.4e-06 26.2 25.7 0.048 13.4 1.2 8.4 3 3 3 8 8 8 3 26S proteasome subunit RPN7 TPR_17 PF13431.6 OWF55333.1 - 1.2e-05 25.3 30.5 0.091 13.2 0.1 12.8 15 0 0 15 15 12 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF55333.1 - 0.0082 16.6 50.7 0.057 13.9 0.1 13.0 11 5 6 17 17 16 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OWF55333.1 - 0.099 13.1 6.4 10 6.5 0.2 5.0 4 2 1 5 5 5 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 OWF55333.1 - 0.12 13.1 40.7 24 5.9 0.0 13.9 15 0 0 15 15 13 0 Tetratricopeptide repeat PUB PF09409.10 OWF55333.1 - 0.15 12.0 0.0 0.9 9.5 0.0 2.1 2 0 0 2 2 2 0 PUB domain TPR_9 PF13371.6 OWF55333.1 - 0.21 11.7 27.3 6.7 6.9 0.0 10.9 12 3 1 14 14 12 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OWF55333.1 - 1.2 9.2 37.9 4.4 7.4 0.3 10.0 7 3 2 9 9 9 0 Anaphase-promoting complex subunit 5 HEAT_PBS PF03130.16 OWF55333.1 - 4.7 8.2 5.6 91 4.2 0.0 5.2 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat BTB_2 PF02214.22 OWF55334.1 - 4.3e-19 68.6 0.0 8e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OWF55334.1 - 0.0032 17.7 0.1 0.019 15.2 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain BTB_3 PF16017.5 OWF55334.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain IFT20 PF14931.6 OWF55335.1 - 8.6e-48 161.4 13.9 9.7e-48 161.3 13.9 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 MethyTransf_Reg PF10119.9 OWF55335.1 - 0.058 14.1 0.4 0.33 11.7 0.1 2.1 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain Rho_Binding PF08912.11 OWF55335.1 - 7.7 7.4 17.6 3.9 8.3 13.0 2.4 1 1 0 2 2 2 0 Rho Binding Clathrin_propel PF01394.20 OWF55336.1 - 0.00095 19.4 0.1 74 3.9 0.1 5.3 6 0 0 6 6 6 1 Clathrin propeller repeat Hira PF07569.11 OWF55336.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split SBDS_C PF09377.10 OWF55337.1 - 2.7e-37 127.3 1.3 4.6e-37 126.6 1.3 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 OWF55337.1 - 2.5e-33 114.0 0.7 6e-33 112.8 0.7 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TRF PF08558.10 OWF55337.1 - 0.077 12.6 1.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) LRR_6 PF13516.6 OWF55338.1 - 4.7e-26 88.6 13.6 0.00097 19.0 0.0 9.4 10 0 0 10 10 10 7 Leucine Rich repeat EF-hand_1 PF00036.32 OWF55338.1 - 4.3e-10 38.4 1.6 0.00017 20.9 0.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OWF55338.1 - 3.3e-09 35.9 0.9 4.2e-05 23.1 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF55338.1 - 3.4e-09 37.0 0.8 1.1e-08 35.4 0.8 1.9 1 0 0 1 1 1 1 EF-hand domain pair LRR_1 PF00560.33 OWF55338.1 - 1.2e-08 34.3 0.8 0.72 10.6 0.0 6.8 6 1 1 7 7 7 1 Leucine Rich Repeat EF-hand_5 PF13202.6 OWF55338.1 - 9.2e-06 24.9 1.7 0.08 12.5 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OWF55338.1 - 5e-05 23.1 1.1 0.00014 21.7 0.2 2.2 1 1 1 2 2 2 1 EF-hand domain pair LRR_8 PF13855.6 OWF55338.1 - 0.00041 20.0 7.4 0.34 10.7 1.1 4.9 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OWF55338.1 - 0.011 16.1 13.6 0.9 10.1 0.3 5.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Guanylate_kin PF00625.21 OWF55338.1 - 0.096 12.4 0.2 0.71 9.5 0.1 2.3 2 1 1 3 3 3 0 Guanylate kinase CHCH PF06747.13 OWF55340.1 - 9.6e-05 22.4 4.7 0.00016 21.7 4.7 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 OWF55340.1 - 0.11 12.5 1.4 0.16 12.0 1.4 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Kinesin PF00225.23 OWF55341.1 - 1.6e-96 323.1 0.0 2.2e-96 322.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OWF55341.1 - 1.4e-28 99.8 0.3 2.5e-28 98.9 0.3 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 OWF55341.1 - 5.9e-10 39.3 0.0 2e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SlyX PF04102.12 OWF55341.1 - 0.044 14.4 0.5 0.12 13.0 0.5 1.8 1 0 0 1 1 1 0 SlyX HHH PF00633.23 OWF55341.1 - 0.1 12.5 0.0 7.9 6.6 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif AAA_24 PF13479.6 OWF55341.1 - 0.1 12.3 1.1 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran_CTD PF16326.5 OWF55341.1 - 0.34 11.2 2.1 0.89 9.9 2.1 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain PAXIP1_C PF15364.6 OWF55342.1 - 3e-36 124.7 7.6 4.6e-36 124.1 7.6 1.3 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein Pkinase PF00069.25 OWF55343.1 - 5.9e-64 216.0 0.0 7.2e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55343.1 - 2e-34 119.1 0.0 2.9e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF55343.1 - 0.00039 20.4 0.4 0.00071 19.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF55343.1 - 0.0046 15.9 1.0 0.0072 15.3 1.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OWF55343.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OWF55343.1 - 0.053 12.9 0.2 0.1 12.0 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSR PF03172.13 OWF55343.1 - 0.055 13.6 2.6 0.061 13.5 0.4 2.1 2 0 0 2 2 2 0 HSR domain Pkinase PF00069.25 OWF55344.1 - 2.8e-25 89.2 0.0 4.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55344.1 - 2.8e-17 62.8 0.0 1e-16 61.1 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OWF55344.1 - 0.007 16.3 0.0 3 7.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OWF55344.1 - 0.17 11.5 0.1 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LIM PF00412.22 OWF55345.1 - 6.8e-56 186.4 42.6 9.4e-16 57.8 4.0 4.5 4 0 0 4 4 4 4 LIM domain Paxillin PF03535.13 OWF55345.1 - 7.3e-05 22.8 21.7 7.3e-05 22.8 21.7 4.6 2 1 1 3 3 3 1 Paxillin family Tfb4 PF03850.14 OWF55346.1 - 2.1e-85 286.6 0.0 2.6e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 GST_N PF02798.20 OWF55347.1 - 1.4e-12 47.8 0.0 4.8e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF55347.1 - 2.1e-11 44.1 0.0 5.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF55347.1 - 3.8e-08 33.5 0.0 8.8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF55347.1 - 0.0084 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OWF55347.1 - 0.014 15.6 0.0 0.041 14.1 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glyco_transf_10 PF00852.19 OWF55348.1 - 3.4e-48 163.7 0.6 6.2e-48 162.8 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF55348.1 - 5.8e-19 68.6 0.5 1.8e-18 67.0 0.1 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 OWF55349.1 - 7.8e-27 94.1 0.1 7.8e-27 94.1 0.1 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF55349.1 - 2.7e-18 66.4 1.0 3.8e-18 65.9 0.2 1.6 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal GST_N_3 PF13417.6 OWF55350.1 - 9.6e-09 35.5 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OWF55350.1 - 1.1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OWF55350.1 - 1.9e-05 24.8 0.0 4.5e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OWF55350.1 - 7.7e-05 22.8 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OWF55350.1 - 8.4e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OWF55350.1 - 0.0046 17.2 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF55350.1 - 0.0051 17.5 0.0 0.031 15.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Otopetrin PF03189.13 OWF55351.1 - 5.9e-21 74.8 30.6 3.9e-20 72.1 10.5 3.0 1 1 2 3 3 3 3 Otopetrin DUF4267 PF14087.6 OWF55351.1 - 0.2 11.7 3.5 0.14 12.2 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) Otopetrin PF03189.13 OWF55352.1 - 7.1e-19 68.0 31.7 8.9e-19 67.6 9.5 3.0 1 1 2 3 3 3 3 Otopetrin HC2 PF07382.11 OWF55353.1 - 2.6 8.1 42.0 3.5 7.7 42.0 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Defensin_1 PF00323.19 OWF55354.1 - 0.011 16.2 3.4 0.011 16.2 3.4 1.6 2 0 0 2 2 2 0 Mammalian defensin GATase PF00117.28 OWF55357.1 - 2.6e-41 141.5 0.0 5.7e-41 140.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 OWF55357.1 - 7.8e-19 67.5 0.5 1.9e-11 43.8 0.0 3.4 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 OWF55357.1 - 1.5e-13 51.1 0.0 2.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 OWF55357.1 - 7.2e-10 38.4 0.1 2.1e-06 27.0 0.1 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 OWF55357.1 - 6.3e-07 29.1 0.0 9.1e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OWF55357.1 - 4.3e-05 22.5 0.2 0.00034 19.5 0.2 2.1 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 OWF55357.1 - 0.00027 20.7 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.19 OWF55357.1 - 0.0011 19.1 0.1 0.0027 17.7 0.0 1.7 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 OWF55357.1 - 0.0016 18.1 0.1 0.004 16.8 0.1 1.8 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 OWF55357.1 - 0.0023 17.7 0.2 0.0053 16.5 0.2 1.7 1 1 0 1 1 1 1 PP-loop family Arginosuc_synth PF00764.19 OWF55357.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase GATase_3 PF07685.14 OWF55357.1 - 0.043 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain LRR_4 PF12799.7 OWF55358.1 - 3e-35 119.7 59.0 2.2e-07 31.1 5.0 6.9 2 1 7 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF55358.1 - 4.7e-25 88.1 17.6 7e-09 35.4 0.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 OWF55358.1 - 5.7e-18 64.4 33.8 2.7e-06 27.1 5.8 6.4 1 1 5 7 7 7 7 Leucine rich repeat LRR_6 PF13516.6 OWF55358.1 - 0.019 15.0 24.5 5.1 7.4 0.1 7.4 7 1 1 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 OWF55358.1 - 0.024 15.1 26.6 5.7 7.9 0.7 8.2 8 1 0 8 8 8 0 Leucine Rich Repeat DUF2322 PF10084.9 OWF55358.1 - 0.23 11.5 2.2 29 4.8 0.1 3.8 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) DUF1647 PF07801.11 OWF55359.1 - 5.7e-06 26.1 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) LIME1 PF15332.6 OWF55359.1 - 0.034 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 adh_short PF00106.25 OWF55360.1 - 1.3e-21 77.0 1.0 6.3e-21 74.7 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF55360.1 - 4.5e-11 42.7 0.1 1.2e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF55360.1 - 0.032 14.1 0.0 0.36 10.7 0.0 2.4 1 1 1 2 2 2 0 KR domain MLD PF11647.8 OWF55362.1 - 0.038 14.3 4.7 1.3 9.3 0.4 4.5 2 0 0 2 2 2 0 Membrane Localization Domain DUF2188 PF09954.9 OWF55362.1 - 5.8 7.1 9.8 0.1 12.8 1.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) TPT PF03151.16 OWF55363.1 - 8.3e-73 245.3 20.0 1e-72 245.0 20.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OWF55363.1 - 1.1e-10 41.9 30.1 1.2e-06 28.8 12.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OWF55363.1 - 1.3e-07 31.2 22.7 2e-07 30.5 22.7 1.3 1 0 0 1 1 1 1 UAA transporter family Ufd2P_core PF10408.9 OWF55364.1 - 3e-199 663.7 16.2 3.6e-199 663.4 16.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OWF55364.1 - 8.3e-29 99.6 0.7 5e-28 97.1 0.5 2.6 2 0 0 2 2 2 1 U-box domain PIN_4 PF13638.6 OWF55364.1 - 0.14 12.5 1.0 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 PIN domain DUF4489 PF14879.6 OWF55365.1 - 1.2e-07 31.9 41.9 0.42 10.7 1.9 6.7 1 1 6 7 7 7 7 Domain of unknown function (DUF4489) RE_LlaMI PF09562.10 OWF55365.1 - 0.7 9.4 19.8 22 4.5 0.1 6.2 1 1 5 7 7 7 0 LlaMI restriction endonuclease DUF5114 PF17141.4 OWF55365.1 - 1.1 9.8 38.9 13 6.4 5.2 7.1 1 1 4 5 5 5 0 Domain of unknown function (DUF5114) PsaF PF17550.2 OWF55366.1 - 0.09 12.3 1.6 2.7 7.5 0.2 3.2 1 1 2 3 3 3 0 Family of unknown function Anthrax_toxA PF03497.16 OWF55366.1 - 0.12 12.5 2.8 13 5.9 0.2 2.8 1 1 2 3 3 3 0 Anthrax toxin LF subunit GMP_PDE_delta PF05351.11 OWF55366.1 - 0.14 12.2 1.8 17 5.4 0.1 2.8 1 1 2 3 3 3 0 GMP-PDE, delta subunit DUF4845 PF16137.5 OWF55366.1 - 0.27 12.1 5.6 19 6.2 0.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4845) ShlB PF03865.13 OWF55366.1 - 0.32 10.4 8.7 0.98 8.8 2.7 2.3 1 1 1 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB VWA_3_C PF18571.1 OWF55366.1 - 1.1 9.1 11.2 9 6.3 0.7 3.8 3 1 1 4 4 4 0 von Willebrand factor type A C-terminal domain DUF2589 PF11655.8 OWF55366.1 - 2.1 8.7 5.4 45 4.4 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2589) 7tm_1 PF00001.21 OWF55367.1 - 1e-23 84.0 22.4 2e-17 63.4 12.0 2.4 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF5474 PF17568.2 OWF55367.1 - 3.2 7.9 6.6 0.43 10.7 2.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5474) Git3 PF11710.8 OWF55367.1 - 7.4 6.3 28.8 1.1 8.9 20.5 2.8 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 zf-C2H2_4 PF13894.6 OWF55369.1 - 1.3e-32 109.6 140.7 0.0012 19.5 0.5 19.0 19 0 0 19 19 19 16 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF55369.1 - 1.5e-25 88.2 127.2 0.00014 22.2 3.8 18.1 18 0 0 18 18 18 11 Zinc finger, C2H2 type zf-Di19 PF05605.12 OWF55369.1 - 8.5e-15 54.8 99.9 6.4e-05 23.2 0.5 12.8 10 2 0 12 12 12 6 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 OWF55369.1 - 6.8e-13 48.4 124.8 0.0045 17.4 0.3 17.5 18 0 0 18 18 18 12 Zinc-finger double domain zf-met PF12874.7 OWF55369.1 - 0.0078 16.6 93.9 0.04 14.3 1.1 16.2 17 0 0 17 17 17 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF55369.1 - 0.037 14.3 93.2 0.05 13.9 0.1 16.0 18 0 0 18 18 18 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 OWF55369.1 - 0.055 13.3 14.5 5.2 6.9 0.0 6.5 5 1 1 6 6 6 0 GAGA factor zf-C2H2_6 PF13912.6 OWF55369.1 - 0.07 13.2 0.1 0.07 13.2 0.1 14.6 16 0 0 16 16 16 0 C2H2-type zinc finger Peptidase_M13_N PF05649.13 OWF55370.1 - 1.2e-107 361.0 0.2 1.7e-107 360.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OWF55370.1 - 3.3e-70 235.9 0.0 1.9e-69 233.4 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M13 TMEM169 PF15052.6 OWF55370.1 - 0.11 12.6 0.3 0.26 11.4 0.3 1.6 1 0 0 1 1 1 0 TMEM169 protein family Sugar_tr PF00083.24 OWF55371.1 - 1.9e-110 369.9 22.5 2.4e-110 369.5 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OWF55371.1 - 1.1e-25 90.4 26.6 3.3e-19 69.0 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec62 PF03839.16 OWF55372.1 - 2.6e-66 223.3 16.0 2.6e-66 223.3 16.0 3.8 2 2 1 3 3 3 1 Translocation protein Sec62 DEP PF00610.21 OWF55372.1 - 8.1e-05 22.6 0.1 0.00028 20.9 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2207 PF09972.9 OWF55372.1 - 0.00025 20.0 0.5 0.00025 20.0 0.5 2.9 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) OPT PF03169.15 OWF55372.1 - 0.0025 16.6 0.0 0.0038 15.9 0.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2052 PF09747.9 OWF55372.1 - 0.006 16.7 18.4 0.006 16.7 18.4 4.0 3 2 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) DUF1403 PF07183.11 OWF55372.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) DUF3413 PF11893.8 OWF55372.1 - 2.7 7.1 5.2 5.1 6.2 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) 7tm_2 PF00002.24 OWF55373.1 - 0.00011 21.5 12.4 0.00014 21.3 12.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 OWF55373.1 - 0.0052 16.1 12.5 0.0072 15.7 11.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 OWF55374.1 - 8.1e-57 192.7 19.7 9.9e-55 185.9 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF55374.1 - 5.7e-15 55.1 5.1 5.7e-15 55.1 5.1 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter BT1 PF03092.16 OWF55374.1 - 8.9e-06 24.2 4.2 0.00027 19.3 0.0 2.9 2 1 1 3 3 3 2 BT1 family SpoVAE PF14097.6 OWF55375.1 - 0.0013 18.5 2.7 1.4 8.5 0.2 3.4 1 1 2 3 3 3 2 Stage V sporulation protein AE1 NPHI_C PF08469.10 OWF55375.1 - 0.032 14.2 7.6 5.3 7.0 0.2 3.9 1 1 2 4 4 4 0 Nucleoside triphosphatase I C-terminal TMEM107 PF14995.6 OWF55375.1 - 0.16 12.4 7.0 1.1 9.7 1.5 2.1 1 1 1 2 2 2 0 Transmembrane protein DUF2284 PF10050.9 OWF55375.1 - 1.6 8.4 3.8 17 5.1 0.3 2.4 1 1 0 2 2 2 0 Predicted metal-binding protein (DUF2284) 7tm_1 PF00001.21 OWF55376.1 - 2.5e-59 200.8 17.4 3.4e-59 200.3 17.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF55376.1 - 1.1e-11 44.6 15.7 2.3e-11 43.6 15.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF55376.1 - 2e-07 30.9 15.7 2e-07 30.9 15.7 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF55376.1 - 9.4e-05 22.3 14.5 0.0025 17.6 14.5 2.3 1 1 0 1 1 1 1 Olfactory receptor ALG3 PF05208.13 OWF55377.1 - 2.2e-140 468.1 28.4 2.8e-140 467.8 28.4 1.0 1 0 0 1 1 1 1 ALG3 protein Folate_rec PF03024.14 OWF55378.1 - 1.1e-16 61.2 11.2 1.5e-16 60.8 11.2 1.2 1 0 0 1 1 1 1 Folate receptor family DUF5030 PF16433.5 OWF55378.1 - 0.039 13.3 0.6 0.05 12.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) DUF4298 PF14131.6 OWF55379.1 - 0.54 10.3 6.5 82 3.3 0.1 4.9 1 1 5 6 6 6 0 Domain of unknown function (DUF4298) PetN PF03742.14 OWF55379.1 - 0.58 10.1 18.3 7.8 6.5 0.1 5.8 7 0 0 7 7 7 0 PetN DltD PF04914.12 OWF55379.1 - 6.3 6.1 8.8 42 3.4 0.1 3.9 2 1 2 4 4 4 0 DltD protein RCC1 PF00415.18 OWF55381.1 - 6.6e-55 183.5 15.1 6e-12 46.0 0.0 7.0 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF55381.1 - 1.1e-28 98.4 12.3 3.7e-08 33.0 0.1 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat CSN7a_helixI PF18392.1 OWF55382.1 - 2.2e-21 75.5 4.7 4.1e-21 74.6 4.7 1.5 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 OWF55382.1 - 2.3e-07 31.3 0.0 5.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain Raptor_N PF14538.6 OWF55382.1 - 0.073 13.0 0.4 0.14 12.1 0.3 1.5 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Arm-DNA-bind_5 PF17293.2 OWF55382.1 - 2.2 8.8 6.7 4 7.9 6.7 1.5 1 1 0 1 1 1 0 Arm DNA-binding domain Pkinase PF00069.25 OWF55383.1 - 5.2e-19 68.6 0.0 1.8e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55383.1 - 1.4e-10 40.9 0.0 2.9e-09 36.6 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OWF55383.1 - 0.0012 18.8 0.4 0.0024 17.9 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF55383.1 - 0.0021 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF3432 PF11914.8 OWF55384.1 - 0.00034 20.8 65.8 0.046 14.0 7.9 5.6 3 2 2 5 5 5 3 Domain of unknown function (DUF3432) Lectin_C PF00059.21 OWF55385.1 - 6.2e-10 39.8 0.5 6.2e-10 39.8 0.5 1.4 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 OWF55385.1 - 6.9e-06 25.8 0.0 7.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF5075 PF16825.5 OWF55385.1 - 0.016 15.0 0.1 0.12 12.0 0.0 2.3 2 1 1 3 3 3 0 IGP family C-type lectin domain Lectin_C PF00059.21 OWF55386.1 - 3.6e-09 37.3 0.2 3.6e-09 37.3 0.2 1.5 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 OWF55386.1 - 0.01 15.5 0.1 0.011 15.4 0.1 1.2 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF55386.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DnaJ PF00226.31 OWF55387.1 - 2e-15 56.6 0.0 3.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain EamA PF00892.20 OWF55387.1 - 0.2 11.8 8.9 2.2 8.4 1.5 2.3 2 0 0 2 2 2 0 EamA-like transporter family DUF3681 PF12442.8 OWF55387.1 - 1.8 9.1 6.8 4.6 7.8 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) Lectin_C PF00059.21 OWF55388.1 - 1.5e-09 38.6 0.4 2.3e-09 37.9 0.0 1.5 2 0 0 2 2 2 1 Lectin C-type domain DUF5075 PF16825.5 OWF55388.1 - 0.0024 17.6 0.1 0.013 15.2 0.0 1.9 1 1 1 2 2 2 1 IGP family C-type lectin domain UL45 PF05473.12 OWF55388.1 - 0.0034 17.0 0.1 0.0058 16.3 0.0 1.4 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF2673 PF10880.8 OWF55389.1 - 0.11 12.6 17.7 0.92 9.7 5.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2673) SF3b10 PF07189.11 OWF55389.1 - 0.62 10.2 8.1 15 5.8 0.3 4.1 1 1 3 4 4 4 0 Splicing factor 3B subunit 10 (SF3b10) YdfZ PF14001.6 OWF55389.1 - 1.2 9.6 11.4 21 5.6 0.2 4.5 1 1 4 5 5 5 0 YdfZ protein YajC PF02699.15 OWF55389.1 - 1.3 8.9 5.0 4.5 7.2 0.6 3.2 1 1 1 2 2 2 0 Preprotein translocase subunit OapA PF04225.12 OWF55390.1 - 0.0092 16.1 9.2 6.9 6.8 0.3 5.1 1 1 5 6 6 6 1 Opacity-associated protein A LysM-like domain DUF4548 PF15081.6 OWF55390.1 - 0.013 15.4 6.7 2.6 7.8 0.3 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4548) DUF2870 PF11069.8 OWF55390.1 - 0.059 13.8 5.2 21 5.6 0.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2870) SpoVIF PF14069.6 OWF55390.1 - 0.19 11.5 32.6 6.3 6.6 0.5 7.1 1 1 5 7 7 7 0 Stage VI sporulation protein F SF3b10 PF07189.11 OWF55390.1 - 0.63 10.2 19.7 29 4.8 0.1 7.1 1 1 5 6 6 6 0 Splicing factor 3B subunit 10 (SF3b10) YdfZ PF14001.6 OWF55390.1 - 1 9.8 20.5 26 5.3 0.3 5.8 1 1 5 6 6 6 0 YdfZ protein BB_PF PF18063.1 OWF55391.1 - 0.0019 17.8 9.3 0.58 9.7 0.4 4.3 1 1 3 4 4 4 2 Beta barrel Pore-forming domain DUF4548 PF15081.6 OWF55391.1 - 0.035 13.9 7.6 4.4 7.1 0.3 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4548) Sec2p PF06428.11 OWF55391.1 - 0.035 14.1 0.8 14 5.7 0.0 3.4 1 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p DUF2673 PF10880.8 OWF55391.1 - 9.3 6.4 24.1 6.1 7.0 0.6 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2673) Orf78 PF06024.12 OWF55392.1 - 0.0021 18.3 0.1 0.0067 16.7 0.0 1.8 2 0 0 2 2 2 1 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 OWF55392.1 - 0.0053 16.5 1.8 0.0095 15.7 1.8 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OWF55392.1 - 0.0065 17.3 0.1 0.027 15.3 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain EGF_CA PF07645.15 OWF55392.1 - 0.022 15.0 5.9 0.022 15.0 5.9 5.0 3 3 1 4 4 4 0 Calcium-binding EGF domain Podoplanin PF05808.11 OWF55392.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Podoplanin DUF4446 PF14584.6 OWF55392.1 - 0.033 14.2 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4695 PF15766.5 OWF55392.1 - 0.06 13.6 2.2 0.099 12.9 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) TMEM154 PF15102.6 OWF55392.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Baculo_VP91_N PF08475.10 OWF55392.1 - 0.27 10.9 2.6 0.41 10.3 1.1 2.1 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal Beta-APP PF03494.13 OWF55392.1 - 0.42 10.5 2.3 0.95 9.4 2.3 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) SKG6 PF08693.10 OWF55392.1 - 2 7.9 8.7 3.5 7.1 8.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4085 PF13315.6 OWF55393.1 - 0.17 11.5 0.2 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Neugrin PF06413.11 OWF55394.1 - 0.11 12.5 1.6 0.16 11.9 1.6 1.2 1 0 0 1 1 1 0 Neugrin NOP5NT PF08156.13 OWF55395.1 - 0.058 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 NOP5NT (NUC127) domain SNF PF00209.18 OWF55396.1 - 5.1e-203 675.5 40.7 5.9e-203 675.3 40.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF55397.1 - 2.1e-204 680.0 38.9 2.8e-204 679.6 38.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 14-3-3 PF00244.20 OWF55398.1 - 1.5e-92 309.1 9.7 1.8e-92 308.9 9.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1572 PF07609.11 OWF55398.1 - 0.051 13.4 1.0 0.074 12.8 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) Salp15 PF12115.8 OWF55398.1 - 0.43 11.0 3.0 5.7 7.4 0.2 2.4 1 1 1 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation HMG_box_2 PF09011.10 OWF55398.1 - 0.58 10.8 6.2 1.2 9.7 1.1 2.9 1 1 1 2 2 2 0 HMG-box domain TPT PF03151.16 OWF55399.1 - 7.5e-19 68.2 24.9 8.6e-19 68.0 24.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OWF55399.1 - 1.8e-09 37.9 35.6 1e-05 25.7 9.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OWF55399.1 - 1.9e-09 37.2 24.7 2.3e-09 36.9 24.7 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 OWF55399.1 - 0.0071 15.6 16.9 0.013 14.7 16.9 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter Phage_holin_2_3 PF16080.5 OWF55399.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Peptidase_C14 PF00656.22 OWF55400.1 - 1.2e-47 163.0 0.1 2.3e-47 162.1 0.1 1.5 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 OWF55400.1 - 5.5e-09 35.9 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 OWF55400.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain WD40 PF00400.32 OWF55401.1 - 1.9e-36 123.4 20.0 7.2e-06 26.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55401.1 - 1.2e-10 41.5 0.1 0.058 13.7 0.1 4.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF55401.1 - 0.00063 19.2 0.0 0.022 14.1 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain Myc-LZ PF02344.15 OWF55401.1 - 0.046 13.8 2.1 0.076 13.1 2.1 1.3 1 0 0 1 1 1 0 Myc leucine zipper domain Lectin_C PF00059.21 OWF55402.1 - 3.8e-10 40.4 0.1 6.4e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain TEP1_N PF05386.11 OWF55403.1 - 0.052 13.1 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 TEP1 N-terminal domain DBP10CT PF08147.12 OWF55403.1 - 0.072 13.3 25.2 8.3 6.7 0.3 6.6 1 1 5 6 6 6 0 DBP10CT (NUC160) domain PLAT PF01477.23 OWF55403.1 - 0.073 13.6 1.5 19 5.8 1.5 3.5 1 1 0 1 1 1 0 PLAT/LH2 domain TPR_22 PF18833.1 OWF55403.1 - 0.64 10.2 40.7 1.3 9.2 1.6 7.6 1 1 8 10 10 10 0 Tetratricopeptide repeat Bud13 PF09736.9 OWF55403.1 - 1.5 9.2 15.0 51 4.2 5.9 3.5 1 1 2 3 3 3 0 Pre-mRNA-splicing factor of RES complex 7TM_GPCR_Srw PF10324.9 OWF55404.1 - 9.9e-28 97.3 19.4 1.5e-27 96.7 19.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 OWF55404.1 - 1.5e-20 73.6 14.3 2e-20 73.2 14.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF55404.1 - 3.4e-05 23.4 19.2 0.0014 18.1 19.2 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF55404.1 - 0.028 14.1 21.5 0.27 10.8 20.9 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx MFS_1 PF07690.16 OWF55405.1 - 7.8e-21 74.4 11.9 1.2e-20 73.8 11.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF55405.1 - 2.2 7.0 17.5 2.9 6.6 15.5 1.8 1 1 1 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 OWF55406.1 - 1.2e-17 63.9 6.1 1.3e-17 63.7 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF55406.1 - 7.3e-07 28.4 4.4 9.9e-07 27.9 4.4 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 OWF55406.1 - 8.8e-07 28.5 4.3 1.1e-06 28.3 4.3 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Nuc_H_symport PF03825.16 OWF55406.1 - 0.0044 16.1 4.2 0.0051 15.9 4.2 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter Sugar_tr PF00083.24 OWF55406.1 - 0.015 14.2 6.4 0.023 13.6 6.4 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter Gpi1 PF05024.15 OWF55406.1 - 0.1 12.7 5.4 0.16 12.0 3.5 2.0 1 1 1 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) DUF3784 PF12650.7 OWF55406.1 - 1.4 9.2 0.0 1.4 9.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) ATG22 PF11700.8 OWF55406.1 - 1.5 7.3 9.3 3.6 6.1 9.3 1.5 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like zf-C4 PF00105.18 OWF55407.1 - 9.6e-20 70.8 15.5 2.2e-19 69.7 15.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF55407.1 - 2.3e-11 43.6 4.6 6.8e-06 25.8 0.0 3.0 3 1 0 3 3 3 2 Ligand-binding domain of nuclear hormone receptor Tetraspanin PF00335.20 OWF55408.1 - 7.7e-31 107.6 16.4 9.6e-31 107.3 16.4 1.1 1 0 0 1 1 1 1 Tetraspanin family KRTAP7 PF15034.6 OWF55408.1 - 0.021 15.7 0.9 0.061 14.3 0.9 1.8 1 0 0 1 1 1 0 KRTAP type 7 family Ldl_recept_b PF00058.17 OWF55409.1 - 6.5e-11 42.5 9.0 0.017 15.6 0.0 7.4 7 0 0 7 7 7 3 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 OWF55409.1 - 2.4e-06 27.7 12.1 7.5e-06 26.1 12.1 1.9 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SGL PF08450.12 OWF55409.1 - 0.00026 20.6 0.2 0.49 9.9 0.0 3.6 4 0 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 OWF55409.1 - 0.041 13.1 2.1 0.29 10.3 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5050) TIG PF01833.24 OWF55410.1 - 8.4e-143 464.8 148.6 3.9e-15 55.7 2.7 16.5 16 0 0 16 16 16 14 IPT/TIG domain G8 PF10162.9 OWF55410.1 - 4.6e-61 204.3 2.6 4.5e-34 117.2 0.4 3.9 3 0 0 3 3 3 2 G8 domain PA14 PF07691.12 OWF55410.1 - 0.00037 20.3 0.1 0.0014 18.5 0.1 2.0 1 0 0 1 1 1 1 PA14 domain Beta_helix PF13229.6 OWF55410.1 - 0.0098 15.8 38.9 0.017 15.0 13.0 6.7 4 2 0 5 5 5 2 Right handed beta helix region DUF2163 PF09931.9 OWF55410.1 - 3.8 7.7 5.5 26 5.0 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2163) Cadherin_C_2 PF16492.5 OWF55410.1 - 4.6 8.1 9.9 0.11 13.3 1.2 2.8 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal zf-TRAF PF02176.18 OWF55411.1 - 3e-12 47.1 15.6 3e-09 37.4 9.1 2.9 1 1 1 2 2 2 2 TRAF-type zinc finger Sina PF03145.16 OWF55411.1 - 0.0016 18.4 12.3 0.0079 16.2 3.0 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-RING_UBOX PF13445.6 OWF55411.1 - 0.012 15.7 5.9 0.033 14.2 5.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF55411.1 - 0.84 9.8 10.8 0.19 11.9 6.6 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF334 PF03904.13 OWF55411.1 - 1 8.8 6.0 1.6 8.2 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Sas6_CC PF18594.1 OWF55411.1 - 5.4 6.9 6.3 0.61 9.9 0.8 2.3 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Ig_3 PF13927.6 OWF55412.1 - 0.00088 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 OWF55412.1 - 0.002 18.2 0.0 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 OWF55412.1 - 0.055 13.6 0.1 0.17 12.0 0.1 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain zf-UBR PF02207.20 OWF55413.1 - 3.7e-12 46.2 12.7 3.7e-12 46.2 12.7 3.4 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 OWF55413.1 - 0.0013 18.5 4.3 0.0013 18.5 4.3 3.5 3 0 0 3 3 3 1 PHD-finger DUF296 PF03479.15 OWF55414.1 - 3.2e-29 101.4 1.4 3.8e-29 101.2 1.4 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain TPD52 PF04201.15 OWF55414.1 - 0.19 11.3 0.8 0.44 10.2 0.8 1.6 1 1 0 1 1 1 0 Tumour protein D52 family Cofilin_ADF PF00241.20 OWF55415.1 - 9e-35 119.1 0.4 1.1e-34 118.9 0.4 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein T3SSipB PF16535.5 OWF55415.1 - 0.058 13.9 0.2 0.28 11.7 0.1 1.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB Arm-DNA-bind_2 PF12167.8 OWF55415.1 - 0.065 13.2 0.1 0.4 10.6 0.0 2.3 2 1 1 3 3 3 0 Arm DNA-binding domain Patched PF02460.18 OWF55417.1 - 3.1e-33 114.9 15.9 1.1e-26 93.3 0.0 2.7 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.8 OWF55417.1 - 1.6e-13 50.8 9.8 1.6e-13 50.8 9.8 3.2 3 1 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OWF55417.1 - 5.2e-09 35.5 17.2 3.5e-06 26.2 4.5 2.4 2 0 0 2 2 2 2 MMPL family Pox_I5 PF04713.12 OWF55417.1 - 0.076 13.1 1.1 0.37 10.9 1.1 2.2 1 0 0 1 1 1 0 Poxvirus protein I5 ACR_tran PF00873.19 OWF55417.1 - 0.13 9.8 2.7 0.22 9.2 2.7 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Arf PF00025.21 OWF55418.1 - 8.1e-60 201.2 0.0 1e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF55418.1 - 1.5e-15 57.4 0.0 2.1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF55418.1 - 5.7e-13 48.8 0.0 6.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF55418.1 - 1.4e-12 47.4 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OWF55418.1 - 1.2e-09 37.8 0.0 3.8e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OWF55418.1 - 1.1e-08 34.7 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OWF55418.1 - 1.5e-05 25.0 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF55418.1 - 0.0031 17.3 0.0 0.0067 16.2 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 OWF55418.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.18 OWF55418.1 - 0.16 11.5 0.2 0.99 8.9 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B PMP22_Claudin PF00822.20 OWF55419.1 - 3.4e-06 27.0 18.5 4.6e-05 23.3 18.5 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF55419.1 - 3.3e-05 23.7 29.0 0.048 13.4 28.0 3.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 OWF55419.1 - 4.1e-05 23.8 4.7 4.1e-05 23.8 4.7 2.2 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.11 OWF55419.1 - 0.00012 22.0 21.8 0.00029 20.8 21.8 1.6 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF973 PF06157.11 OWF55419.1 - 0.002 17.2 9.1 0.003 16.7 9.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Phage_holin_3_2 PF04550.12 OWF55419.1 - 0.0075 16.8 4.0 0.016 15.7 4.0 1.6 1 0 0 1 1 1 1 Phage holin family 2 DUF2070 PF09843.9 OWF55419.1 - 0.015 13.6 11.1 0.015 13.6 11.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MARVEL PF01284.23 OWF55419.1 - 0.12 12.4 21.4 0.84 9.7 21.4 2.2 1 1 0 1 1 1 0 Membrane-associating domain Otopetrin PF03189.13 OWF55419.1 - 1.1 8.0 9.5 1.3 7.8 9.5 1.1 1 0 0 1 1 1 0 Otopetrin Wzy_C PF04932.15 OWF55419.1 - 7 6.3 15.6 1.3 8.7 1.4 2.3 1 1 1 2 2 2 0 O-Antigen ligase DUF5592 PF17332.2 OWF55419.1 - 9.3 6.9 9.9 31 5.2 9.8 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5592) ThiF PF00899.21 OWF55420.1 - 2.1e-39 135.4 0.0 2.8e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family HHH_5 PF14520.6 OWF55420.1 - 0.1 13.2 0.1 2.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain Ribosomal_L4 PF00573.22 OWF55421.1 - 1.1e-41 142.6 0.0 1.7e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family HYLS1_C PF15311.6 OWF55422.1 - 1.8e-33 115.1 7.8 1.8e-33 115.1 7.8 2.0 2 0 0 2 2 2 1 Hydrolethalus syndrome protein 1 C-terminus Pkinase PF00069.25 OWF55423.1 - 8.6e-65 218.7 0.1 1.2e-64 218.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55423.1 - 3.2e-42 144.6 0.1 4.6e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF55423.1 - 0.00021 20.7 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF55423.1 - 0.0084 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF55423.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family FYVE PF01363.21 OWF55424.1 - 3.9e-14 52.5 15.0 3.9e-14 52.5 15.0 3.0 3 0 0 3 3 3 1 FYVE zinc finger DUF547 PF04784.14 OWF55424.1 - 1.3e-13 51.1 0.0 4.6e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF547 TPR_2 PF07719.17 OWF55424.1 - 0.04 14.0 0.1 2.8 8.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat FYVE_2 PF02318.16 OWF55424.1 - 0.34 11.1 9.8 3.1 8.0 9.7 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger Linker_histone PF00538.19 OWF55425.1 - 2.4e-22 79.1 1.0 2.4e-22 79.1 1.0 2.7 3 1 0 3 3 3 1 linker histone H1 and H5 family Vps51 PF08700.11 OWF55425.1 - 0.19 11.8 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Vps51/Vps67 DNA_pol_delta_4 PF04081.13 OWF55425.1 - 3.8 7.8 14.3 0.95 9.8 11.1 1.6 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 Aldose_epim PF01263.20 OWF55426.1 - 3.7e-94 315.4 0.1 4.2e-94 315.2 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Paz_1 PF18349.1 OWF55427.1 - 0.024 14.6 0.2 0.074 13.0 0.2 1.9 1 0 0 1 1 1 0 PAZ domain Utp12 PF04003.12 OWF55429.1 - 1.4e-08 35.0 7.2 3.4 8.0 0.1 5.2 1 1 6 7 7 7 7 Dip2/Utp12 Family YrvL PF14184.6 OWF55429.1 - 0.012 15.7 34.3 4.5 7.4 3.7 5.1 1 1 5 6 6 6 0 Regulatory protein YrvL HD PF01966.22 OWF55430.1 - 1.3e-08 35.1 0.2 2.8e-08 34.0 0.2 1.6 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 OWF55430.1 - 0.00058 19.4 0.0 0.0062 16.0 0.0 2.1 1 1 0 1 1 1 1 HDOD domain DUF3921 PF13060.6 OWF55430.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) HD PF01966.22 OWF55431.1 - 5.8e-08 33.0 0.0 1.5e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 OWF55431.1 - 0.018 14.6 0.0 0.93 8.9 0.0 2.1 1 1 0 1 1 1 0 HDOD domain zf-FCS PF06467.14 OWF55432.1 - 0.024 14.6 10.0 2.6 8.1 0.4 3.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.6 OWF55432.1 - 0.025 15.4 2.2 0.025 15.4 2.2 7.7 8 0 0 8 8 8 0 C2H2-type zinc finger zf-Di19 PF05605.12 OWF55432.1 - 0.2 12.0 35.3 0.19 12.1 3.7 5.4 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 OWF55432.1 - 1.3 9.5 0.0 1.3 9.5 0.0 5.0 4 1 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger adh_short PF00106.25 OWF55433.1 - 1.6e-24 86.5 1.0 1.9e-23 82.9 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF55433.1 - 5.5e-17 62.1 0.0 5.7e-16 58.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF55433.1 - 4.4e-08 33.2 0.1 6.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF55433.1 - 2.8e-06 27.0 0.1 5.4e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OWF55433.1 - 8.5e-05 22.1 0.1 0.00016 21.2 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Clat_adaptor_s PF01217.20 OWF55434.1 - 8.1e-58 194.4 1.1 9.6e-58 194.1 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 OWF55434.1 - 0.0051 15.4 0.2 0.0062 15.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) CNOT1_HEAT PF16418.5 OWF55434.1 - 0.075 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat YmaF PF12788.7 OWF55435.1 - 2.4e-09 37.6 89.3 0.019 15.5 19.9 6.3 1 1 6 7 7 7 7 YmaF family PemK_toxin PF02452.17 OWF55436.1 - 0.35 11.3 12.0 9.9 6.6 0.4 4.9 1 1 2 3 3 3 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system YmaF PF12788.7 OWF55436.1 - 2.5 8.7 56.0 0.82 10.2 16.1 3.9 1 1 3 4 4 4 0 YmaF family DUF4573 PF15140.6 OWF55437.1 - 3.4e-10 40.0 16.3 5.6e-07 29.5 8.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) YhdB PF14148.6 OWF55437.1 - 0.081 13.0 1.2 82 3.4 0.1 4.4 2 2 4 6 6 6 0 YhdB-like protein Cas9_Topo PF17894.1 OWF55437.1 - 0.1 12.7 11.9 4.1 7.5 0.4 4.9 1 1 4 5 5 5 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 ITAM PF02189.15 OWF55437.1 - 0.25 11.9 15.3 46 4.7 0.1 8.2 4 4 8 12 12 12 0 Immunoreceptor tyrosine-based activation motif TMEM108 PF15759.5 OWF55437.1 - 3.8 6.4 23.3 5 6.0 3.6 3.2 1 1 2 3 3 3 0 TMEM108 family Glyco_transf_10 PF00852.19 OWF55438.1 - 6.5e-58 195.3 0.8 6.5e-58 195.3 0.8 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF55438.1 - 8.9e-17 61.5 0.2 8.9e-17 61.5 0.2 2.2 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal Euplotes_phero PF05842.11 OWF55438.1 - 0.0031 18.1 1.0 0.0055 17.3 1.0 1.3 1 0 0 1 1 1 1 Euplotes octocarinatus mating pheromone protein Hormone_3 PF00159.18 OWF55438.1 - 0.009 16.1 1.5 0.2 11.7 0.2 2.7 2 0 0 2 2 2 1 Pancreatic hormone peptide Glyco_transf_11 PF01531.16 OWF55439.1 - 9.8e-41 139.9 0.0 1.1e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 OWF55439.1 - 1.1e-06 28.7 0.1 1.2e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3158 PF11358.8 OWF55439.1 - 0.049 13.4 0.5 0.077 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) GTP_EFTU PF00009.27 OWF55440.1 - 7.6e-61 205.0 0.1 1.3e-60 204.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OWF55440.1 - 9.6e-34 115.8 0.1 2e-33 114.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 OWF55440.1 - 8.8e-26 89.8 0.0 2.2e-25 88.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OWF55440.1 - 7.7e-22 77.1 0.1 1.8e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OWF55440.1 - 2.1e-11 44.1 0.0 4.7e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OWF55440.1 - 3.3e-06 26.9 0.0 1.4e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 OWF55440.1 - 0.00031 20.8 0.2 0.0009 19.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 OWF55440.1 - 0.0017 17.7 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AvrPtoB_bdg PF16847.5 OWF55440.1 - 0.048 14.1 0.0 2.1 8.9 0.0 2.9 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain Ada3 PF10198.9 OWF55440.1 - 0.13 12.4 1.4 13 5.9 0.7 2.4 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Ank_2 PF12796.7 OWF55441.1 - 1.8e-38 131.0 5.7 6.6e-15 55.5 0.1 4.7 2 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55441.1 - 5.5e-31 106.5 2.7 1.4e-10 41.4 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OWF55441.1 - 2.5e-26 90.9 6.2 2.5e-05 24.5 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OWF55441.1 - 1.2e-24 86.0 1.7 1.4e-12 47.6 0.1 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55441.1 - 2.1e-21 73.7 1.7 0.00055 20.2 0.1 6.8 7 0 0 7 7 7 4 Ankyrin repeat TAN PF11640.8 OWF55441.1 - 0.056 13.6 0.1 0.091 12.9 0.1 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF229 PF02995.17 OWF55442.1 - 1.3e-108 363.8 0.5 2.5e-108 362.9 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 OWF55442.1 - 2.1e-12 47.1 0.3 3e-12 46.6 0.3 1.3 1 0 0 1 1 1 1 Sulfatase DUF885 PF05960.11 OWF55443.1 - 7.5e-136 454.9 0.0 8.7e-136 454.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF1856 PF08983.10 OWF55443.1 - 0.42 10.9 1.0 0.74 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) zf-H2C2_2 PF13465.6 OWF55444.1 - 7.3e-30 102.1 45.7 5.3e-07 29.8 2.0 7.0 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 OWF55444.1 - 1.9e-27 94.1 43.6 4.9e-05 23.6 0.8 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF55444.1 - 3.8e-22 77.1 41.5 0.00048 20.7 0.8 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF55444.1 - 1.2e-11 44.3 39.4 0.092 12.8 1.1 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF55444.1 - 8.4e-11 41.9 17.6 0.024 14.9 0.0 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 OWF55444.1 - 2.5e-07 30.2 18.1 0.92 9.2 0.1 6.3 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 OWF55444.1 - 7.1e-06 26.0 17.2 0.015 15.4 0.8 4.8 3 3 2 5 5 5 3 Zinc ribbon domain zf-Di19 PF05605.12 OWF55444.1 - 0.0001 22.5 24.0 0.028 14.7 4.6 4.2 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 OWF55444.1 - 0.0012 18.8 25.9 0.24 11.4 2.4 5.4 4 1 2 6 6 5 2 BED zinc finger XPA_N PF01286.18 OWF55444.1 - 0.0053 16.8 20.8 1.5 8.9 0.1 6.3 6 0 0 6 6 6 1 XPA protein N-terminal zf-C2HC_2 PF13913.6 OWF55444.1 - 0.012 15.5 26.4 0.44 10.5 1.4 6.1 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 OWF55444.1 - 0.013 15.2 26.9 0.83 9.5 0.1 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-met PF12874.7 OWF55444.1 - 0.016 15.6 0.5 0.016 15.6 0.5 5.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type HypA PF01155.19 OWF55444.1 - 0.028 14.5 14.1 0.18 11.8 1.1 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 OWF55444.1 - 0.03 15.1 18.0 0.87 10.4 0.9 3.7 1 1 4 5 5 5 0 zinc-ribbon family zf-AN1 PF01428.16 OWF55444.1 - 0.048 13.8 25.5 4.6 7.5 0.2 6.2 6 0 0 6 6 6 0 AN1-like Zinc finger HNH_5 PF14279.6 OWF55444.1 - 0.05 13.5 16.8 6.4 6.7 0.0 5.7 5 1 0 5 5 5 0 HNH endonuclease zf-C2H2_3rep PF18868.1 OWF55444.1 - 0.15 12.7 18.7 0.39 11.4 2.5 4.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 OWF55444.1 - 0.18 11.9 18.1 20 5.2 0.3 5.4 2 1 1 4 4 4 0 CpXC protein zf_C2H2_ZHX PF18387.1 OWF55444.1 - 0.18 11.4 15.5 0.21 11.3 2.5 4.4 3 2 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-CHCC PF10276.9 OWF55444.1 - 0.18 11.9 0.3 0.18 11.9 0.3 4.1 5 0 0 5 5 5 0 Zinc-finger domain zf-C2H2_8 PF15909.5 OWF55444.1 - 0.3 11.4 18.2 2.9 8.3 3.4 3.1 1 1 3 4 4 4 0 C2H2-type zinc ribbon TRAF6_Z2 PF18048.1 OWF55444.1 - 0.56 10.4 14.6 10 6.3 0.2 4.7 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 zf_ZIC PF18366.1 OWF55444.1 - 0.57 10.3 18.2 2.9 8.1 0.3 5.5 3 1 3 6 6 6 0 Zic proteins zinc finger domain GAGA PF09237.11 OWF55444.1 - 0.89 9.4 7.7 6.8 6.6 0.5 3.8 2 1 2 4 4 4 0 GAGA factor zf-C2H2_2 PF12756.7 OWF55444.1 - 0.91 9.9 25.7 19 5.7 0.5 5.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 OWF55444.1 - 0.92 9.6 26.1 1.8e+04 -4.9 26.1 4.1 1 1 0 1 1 0 0 Double zinc ribbon zf-LYAR PF08790.11 OWF55444.1 - 1 9.3 22.7 3.1 7.8 0.1 5.9 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger ADK_lid PF05191.14 OWF55444.1 - 1.6 8.7 17.2 22 5.2 0.2 4.7 2 2 2 4 4 4 0 Adenylate kinase, active site lid FYDLN_acid PF09538.10 OWF55444.1 - 2 9.1 8.1 13 6.6 0.8 4.0 2 2 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Cys_rich_CPXG PF14255.6 OWF55444.1 - 2.6 8.0 9.6 0.92 9.5 0.2 3.7 3 1 1 4 4 3 0 Cysteine-rich CPXCG Endonuclease_7 PF02945.15 OWF55444.1 - 8.4 6.4 17.0 0.66 9.9 2.2 3.1 1 1 2 3 3 3 0 Recombination endonuclease VII bZIP_1 PF00170.21 OWF55445.1 - 0.00025 21.1 1.0 0.0086 16.2 1.1 2.7 2 0 0 2 2 2 1 bZIP transcription factor HALZ PF02183.18 OWF55445.1 - 0.0058 16.8 2.8 0.22 11.7 1.6 2.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper CC2-LZ PF16516.5 OWF55445.1 - 0.017 15.5 0.6 0.017 15.5 0.6 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator XRCC4 PF06632.12 OWF55445.1 - 0.018 13.9 2.1 0.036 12.9 2.1 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cnn_1N PF07989.11 OWF55445.1 - 0.025 14.7 0.1 0.025 14.7 0.1 2.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 OWF55445.1 - 0.044 14.2 9.0 0.21 12.1 4.2 3.1 3 0 0 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 OWF55445.1 - 0.051 13.9 2.4 0.091 13.1 0.5 2.5 3 0 0 3 3 2 0 TSC-22/dip/bun family DivIC PF04977.15 OWF55445.1 - 0.084 12.7 8.5 0.17 11.6 5.7 2.6 1 1 1 2 2 2 0 Septum formation initiator DASH_Hsk3 PF08227.11 OWF55445.1 - 0.14 12.5 3.3 15 6.0 0.0 3.0 3 0 0 3 3 2 0 DASH complex subunit Hsk3 like GOLGA2L5 PF15070.6 OWF55445.1 - 0.16 10.6 12.4 0.59 8.7 1.4 2.1 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF2935 PF11155.8 OWF55445.1 - 0.2 12.0 3.6 0.21 11.9 0.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) KASH_CCD PF14662.6 OWF55445.1 - 0.2 11.4 13.2 1 9.1 4.9 2.3 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cep57_CLD_2 PF14197.6 OWF55445.1 - 0.23 11.6 9.2 0.053 13.6 2.5 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Lzipper-MIP1 PF14389.6 OWF55445.1 - 0.44 10.9 5.8 0.13 12.6 1.1 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 JIP_LZII PF16471.5 OWF55445.1 - 0.51 10.5 10.1 1.7 8.9 0.2 3.6 2 2 1 3 3 3 0 JNK-interacting protein leucine zipper II DUF4618 PF15397.6 OWF55445.1 - 0.96 8.8 12.1 2 7.8 11.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) GrpE PF01025.19 OWF55445.1 - 1.4 8.6 6.0 0.77 9.4 3.4 1.9 2 1 0 2 2 2 0 GrpE Seryl_tRNA_N PF02403.22 OWF55445.1 - 1.6 9.0 7.3 3.5 7.9 0.0 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 OWF55445.1 - 2.3 9.1 10.9 10 7.1 0.4 3.3 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 OWF55445.1 - 2.4 8.2 7.7 14 5.7 2.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 OWF55445.1 - 4.5 8.0 10.6 3e+02 2.1 10.5 2.6 1 1 0 1 1 1 0 Initiation control protein YabA Fungal_TACC PF12709.7 OWF55445.1 - 6.2 7.3 8.7 1.9 9.0 3.9 2.5 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins NDK PF00334.19 OWF55446.1 - 6.6e-77 256.0 0.0 2.3e-40 137.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 OWF55446.1 - 0.00029 20.6 2.2 0.00067 19.5 2.2 1.6 1 0 0 1 1 1 1 DUF1126 PH-like domain DNase_NucA_NucB PF14040.6 OWF55446.1 - 0.085 13.2 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB Ets PF00178.22 OWF55447.1 - 1.1e-34 118.8 3.5 1.7e-34 118.1 2.8 1.7 2 0 0 2 2 2 1 Ets-domain HSF_DNA-bind PF00447.17 OWF55447.1 - 0.047 14.3 0.7 0.083 13.5 0.7 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding DUF3338 PF11819.8 OWF55448.1 - 7.4e-35 119.9 2.1 7.4e-35 119.9 2.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_C PF09380.10 OWF55448.1 - 8.2e-22 77.4 0.1 2.2e-21 76.0 0.1 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 OWF55448.1 - 1.2e-20 74.1 0.0 1.2e-20 74.1 0.0 3.0 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.10 OWF55448.1 - 4.1e-14 52.3 0.3 3.1e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 FERM N-terminal domain RhlB PF12300.8 OWF55448.1 - 0.079 13.1 0.8 0.34 11.0 0.8 2.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Cytochrom_B561 PF03188.16 OWF55449.1 - 2.7e-27 95.6 13.1 2.7e-27 95.6 13.1 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Methyltr_RsmB-F PF01189.17 OWF55450.1 - 0.0039 16.8 0.7 0.89 9.2 0.1 2.4 1 1 2 3 3 3 2 16S rRNA methyltransferase RsmB/F MCD_N PF17408.2 OWF55450.1 - 1.4 9.1 9.9 13 6.0 1.1 3.2 1 1 3 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain Methyltr_RsmB-F PF01189.17 OWF55451.1 - 0.0089 15.7 0.1 1.8 8.2 0.0 2.0 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F QRPTase_N PF02749.16 OWF55451.1 - 0.074 13.1 3.7 34 4.6 0.1 3.8 1 1 3 4 4 4 0 Quinolinate phosphoribosyl transferase, N-terminal domain MCD_N PF17408.2 OWF55451.1 - 0.5 10.5 7.2 23 5.2 0.3 3.2 1 1 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Sulfotransfer_2 PF03567.14 OWF55452.1 - 2.2e-27 96.6 2.5 6.5e-27 95.0 1.2 2.1 1 1 0 2 2 2 1 Sulfotransferase family RNA_lig_T4_1 PF09511.10 OWF55452.1 - 0.075 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 RNA ligase Fibrinogen_C PF00147.18 OWF55453.1 - 2.7e-27 96.0 6.0 3.6e-27 95.6 6.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Sushi PF00084.20 OWF55453.1 - 0.0039 17.7 1.6 0.027 15.1 0.0 2.8 2 1 1 3 3 3 1 Sushi repeat (SCR repeat) DUF1935 PF09149.10 OWF55453.1 - 0.016 15.5 0.3 0.028 14.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) FAM194 PF14977.6 OWF55454.1 - 2.3e-33 115.3 0.0 4e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 FAM194 protein DUF4158 PF13700.6 OWF55454.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) p450 PF00067.22 OWF55455.1 - 1.5e-94 317.4 0.0 2e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AIG1 PF04548.16 OWF55456.1 - 1.7e-57 194.2 2.2 2.5e-57 193.6 2.2 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF55456.1 - 5.6e-10 39.3 0.1 1.6e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF55456.1 - 0.00011 22.2 1.6 0.0002 21.3 0.7 2.0 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OWF55456.1 - 0.0003 20.9 9.3 0.11 12.6 0.3 3.3 2 1 1 3 3 3 2 Dynamin family Septin PF00735.18 OWF55456.1 - 0.00039 19.8 0.4 0.00039 19.8 0.4 1.8 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 OWF55456.1 - 0.0012 18.4 0.7 0.002 17.7 0.1 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 OWF55456.1 - 0.0048 17.4 0.9 0.064 13.8 0.9 2.3 1 1 0 1 1 1 1 ABC transporter DLP_helical PF18709.1 OWF55456.1 - 0.045 12.9 4.2 0.075 12.2 4.2 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain SRPRB PF09439.10 OWF55456.1 - 0.049 13.1 0.7 0.22 10.9 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF4615 PF15393.6 OWF55456.1 - 0.083 13.5 1.1 0.2 12.2 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) AAA_22 PF13401.6 OWF55456.1 - 0.1 12.9 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain HAS-barrel PF09378.10 OWF55456.1 - 0.1 12.8 0.3 0.25 11.5 0.3 1.7 1 0 0 1 1 1 0 HAS barrel domain Bep_C_terminal PF17841.1 OWF55456.1 - 0.11 12.7 0.6 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) APG6_N PF17675.1 OWF55456.1 - 0.11 13.0 1.9 0.2 12.2 1.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region ResIII PF04851.15 OWF55456.1 - 0.22 11.5 2.9 1.9 8.5 0.1 2.7 1 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 OWF55456.1 - 0.26 11.0 2.8 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 OWF55456.1 - 0.38 10.8 4.9 0.63 10.1 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TQ PF18202.1 OWF55456.1 - 0.42 11.2 0.1 0.42 11.2 0.1 2.6 4 1 0 4 4 3 0 T-Q ester bond containing domain Aa_trans PF01490.18 OWF55457.1 - 5.5e-63 213.1 35.3 6.8e-63 212.8 35.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OWF55457.1 - 0.23 10.4 31.0 0.0057 15.7 20.1 2.3 1 1 0 2 2 2 0 Tryptophan/tyrosine permease family Tubulin-binding PF00418.19 OWF55458.1 - 5.3e-78 256.7 33.4 5.5e-08 32.7 0.2 12.9 13 0 0 13 13 13 12 Tau and MAP protein, tubulin-binding repeat ABC_membrane PF00664.23 OWF55459.1 - 4.2e-130 433.3 35.2 4.6e-75 252.8 11.5 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF55459.1 - 1.5e-60 203.7 2.7 5.8e-36 124.0 0.1 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OWF55459.1 - 3e-10 39.9 0.0 2e-07 30.6 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OWF55459.1 - 1.4e-08 35.3 0.2 0.0055 17.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OWF55459.1 - 3.6e-07 30.3 0.0 0.0093 15.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 OWF55459.1 - 1e-06 28.2 0.1 0.011 15.0 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.6 OWF55459.1 - 1.2e-06 28.9 0.1 0.018 15.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OWF55459.1 - 2.1e-06 27.4 0.1 0.036 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 OWF55459.1 - 2.3e-06 27.7 0.1 0.12 12.3 0.0 2.8 2 1 0 2 2 2 2 Rad17 P-loop domain G-alpha PF00503.20 OWF55459.1 - 3.2e-06 26.5 0.0 0.053 12.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 OWF55459.1 - 5.3e-06 26.3 1.9 0.13 12.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 OWF55459.1 - 1.3e-05 24.2 0.0 0.0001 21.2 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.14 OWF55459.1 - 1.6e-05 24.9 0.1 0.47 10.4 0.0 3.4 3 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 OWF55459.1 - 4.9e-05 23.2 2.9 0.099 12.3 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 OWF55459.1 - 0.00013 22.4 0.4 1.7 9.1 0.2 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OWF55459.1 - 0.00014 21.4 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP-synt_ab PF00006.25 OWF55459.1 - 0.0011 18.7 0.1 0.45 10.1 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 OWF55459.1 - 0.0018 17.9 0.1 2.8 7.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain DUF815 PF05673.13 OWF55459.1 - 0.0019 17.4 0.0 0.56 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OWF55459.1 - 0.0019 18.5 0.1 2.4 8.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.6 OWF55459.1 - 0.0021 18.3 0.0 5.1 7.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 OWF55459.1 - 0.0028 17.4 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 OWF55459.1 - 0.0033 17.6 2.5 1.2 9.2 0.0 3.0 4 0 0 4 4 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 OWF55459.1 - 0.0054 16.5 0.2 4.1 7.1 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 OWF55459.1 - 0.0081 16.1 0.3 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 OWF55459.1 - 0.011 14.9 0.1 1.7 7.8 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 OWF55459.1 - 0.014 15.9 0.0 8.6 6.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 OWF55459.1 - 0.018 14.1 0.0 0.64 9.0 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 OWF55459.1 - 0.022 14.9 0.3 16 5.7 0.4 3.1 2 1 1 3 3 2 0 AAA domain AAA_24 PF13479.6 OWF55459.1 - 0.026 14.2 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 OWF55459.1 - 0.043 13.6 0.0 13 5.5 0.0 3.2 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OWF55459.1 - 0.044 14.3 0.1 21 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 OWF55459.1 - 0.058 13.3 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activat PF00158.26 OWF55459.1 - 0.07 12.8 0.0 5.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain tRNA_lig_kinase PF08303.11 OWF55459.1 - 0.086 12.9 0.0 23 5.0 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain MMR_HSR1 PF01926.23 OWF55459.1 - 0.13 12.3 0.2 16 5.6 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase TsaE PF02367.17 OWF55459.1 - 0.15 12.1 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 OWF55459.1 - 3 8.2 6.4 0.49 10.7 0.5 2.6 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.23 OWF55460.1 - 4e-148 492.4 20.1 3e-77 259.9 4.7 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF55460.1 - 2.2e-57 193.4 0.1 2.2e-37 128.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF55460.1 - 4.9e-17 62.1 0.5 2.8e-07 30.2 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OWF55460.1 - 2.7e-08 33.0 0.7 0.00016 20.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 OWF55460.1 - 2.7e-05 24.6 0.0 0.032 14.7 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OWF55460.1 - 5.3e-05 23.7 0.8 0.00028 21.3 0.2 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 OWF55460.1 - 6.4e-05 23.1 6.5 0.32 11.3 0.6 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 OWF55460.1 - 0.0001 22.2 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OWF55460.1 - 0.00051 20.3 0.2 0.012 15.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OWF55460.1 - 0.011 15.4 0.2 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OWF55460.1 - 0.015 14.6 1.1 0.22 10.8 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin G-alpha PF00503.20 OWF55460.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit IstB_IS21 PF01695.17 OWF55460.1 - 0.017 14.8 0.5 3.4 7.4 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 OWF55460.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 OWF55460.1 - 0.019 14.9 0.1 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 OWF55460.1 - 0.019 14.9 0.3 0.23 11.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OWF55460.1 - 0.028 14.1 1.3 0.23 11.2 0.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OWF55460.1 - 0.054 13.7 0.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OWF55460.1 - 0.09 12.3 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OWF55460.1 - 0.11 12.6 0.0 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 OWF55460.1 - 0.12 12.1 0.4 0.23 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain DUF4710 PF15828.5 OWF55460.1 - 0.12 12.6 0.9 34 4.6 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF87 PF01935.17 OWF55460.1 - 0.16 12.0 0.4 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain DUF2852 PF11014.8 OWF55460.1 - 0.84 9.8 2.6 10 6.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DnaJ PF00226.31 OWF55461.1 - 5.7e-29 100.0 2.8 8.2e-29 99.5 2.8 1.2 1 0 0 1 1 1 1 DnaJ domain CLP1_P PF16575.5 OWF55462.1 - 5.4e-70 235.0 0.0 1e-69 234.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 OWF55462.1 - 4.3e-27 94.9 0.1 6.7e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 OWF55462.1 - 9.7e-27 93.0 0.1 1.5e-26 92.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 OWF55462.1 - 0.00047 20.2 0.0 0.0013 18.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OWF55462.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TniB PF05621.11 OWF55462.1 - 0.0095 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 OWF55462.1 - 0.016 15.0 0.0 0.063 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 OWF55462.1 - 0.039 14.0 0.0 0.054 13.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 OWF55462.1 - 0.071 12.8 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 OWF55462.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 OWF55462.1 - 0.081 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 OWF55462.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OWF55462.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tubulin_C PF03953.17 OWF55464.1 - 0.017 15.3 0.4 0.04 14.1 0.4 1.6 1 0 0 1 1 1 0 Tubulin C-terminal domain NHL PF01436.21 OWF55464.1 - 0.017 15.1 1.2 6.9 6.9 0.0 3.6 3 0 0 3 3 3 0 NHL repeat BUD22 PF09073.10 OWF55464.1 - 0.097 12.0 12.9 0.17 11.2 12.9 1.4 1 0 0 1 1 1 0 BUD22 Noelin-1 PF12308.8 OWF55464.1 - 0.21 11.6 3.0 0.27 11.3 0.5 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein THP2 PF09432.10 OWF55464.1 - 0.25 11.4 4.9 0.25 11.4 1.1 2.4 1 1 1 2 2 2 0 Tho complex subunit THP2 Presenilin PF01080.17 OWF55464.1 - 4.2 6.0 5.5 10 4.7 5.5 1.6 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 OWF55465.1 - 4.1e-20 72.0 29.4 4.1e-20 72.0 29.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2615 PF11027.8 OWF55465.1 - 0.18 12.0 0.0 32 4.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Phage_holin_1 PF04531.13 OWF55465.1 - 0.32 11.6 1.7 1.8 9.2 1.7 2.3 1 0 0 1 1 1 0 Bacteriophage holin Pox_A14 PF05767.12 OWF55465.1 - 9.3 6.5 15.5 16 5.7 0.0 4.7 4 1 1 5 5 5 0 Poxvirus virion envelope protein A14 MFS_1 PF07690.16 OWF55467.1 - 5.2e-06 25.6 9.7 6.7e-06 25.3 9.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OWF55468.1 - 1.2e-11 44.2 5.8 1.3e-11 44.0 5.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF55468.1 - 0.00049 19.1 1.0 0.0013 17.7 0.5 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OWF55468.1 - 0.0022 17.4 0.7 0.0025 17.2 0.1 1.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 OWF55469.1 - 1.9e-10 40.6 0.0 5e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55469.1 - 1.1e-07 31.4 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF55470.1 - 2e-35 122.5 0.0 3e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55470.1 - 3.8e-18 65.7 0.1 6.5e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.9 OWF55472.1 - 0.086 13.4 0.1 0.31 11.7 0.1 2.0 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF4061 PF13270.6 OWF55472.1 - 9.9 6.6 8.5 2.3 8.6 2.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF4174 PF13778.6 OWF55473.1 - 1.3e-16 61.1 104.3 8.4 6.9 0.4 23.6 1 1 26 27 27 27 27 Domain of unknown function (DUF4174) SIP1 PF04938.12 OWF55474.1 - 5.2e-64 215.9 0.0 6.3e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) VirE_N PF08800.10 OWF55474.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 1 0 1 1 1 0 VirE N-terminal domain Polyketide_cyc PF03364.20 OWF55475.1 - 2.5e-23 82.7 0.0 3.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.11 OWF55475.1 - 0.029 14.2 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1857) SF3b1 PF08920.10 OWF55476.1 - 7.9e-43 145.7 51.8 1.3e-41 141.8 19.1 5.7 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 OWF55476.1 - 4.8e-09 36.5 2.1 0.032 14.6 0.0 6.7 5 2 2 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 OWF55476.1 - 8e-09 35.8 1.5 0.56 10.8 0.0 7.0 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 OWF55476.1 - 1.6e-08 34.1 6.2 0.71 10.3 0.1 8.0 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 OWF55476.1 - 1.1e-05 26.0 0.6 0.68 10.6 0.0 4.5 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OWF55476.1 - 0.00018 21.6 7.5 1.5 8.8 0.0 5.4 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 OWF55476.1 - 0.00073 19.5 3.4 1.7 8.5 0.1 4.9 3 1 2 5 5 5 2 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 OWF55476.1 - 0.0011 17.6 0.0 0.0053 15.4 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region CLASP_N PF12348.8 OWF55476.1 - 0.0012 18.5 1.1 4.2 6.9 0.1 3.3 3 0 0 3 3 3 2 CLASP N terminal TAF6_C PF07571.13 OWF55476.1 - 0.0067 16.7 0.1 0.26 11.7 0.0 3.1 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain NUC173 PF08161.12 OWF55476.1 - 0.038 13.6 0.3 2.8 7.5 0.0 3.8 4 1 1 5 5 5 0 NUC173 domain UNC45-central PF11701.8 OWF55476.1 - 0.049 13.6 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DRIM PF07539.12 OWF55476.1 - 0.063 11.6 0.1 9.1 4.4 0.0 3.1 2 1 0 3 3 3 0 Down-regulated in metastasis Dor1 PF04124.12 OWF55476.1 - 0.092 11.4 0.1 6.3 5.4 0.0 2.4 2 0 0 2 2 2 0 Dor1-like family DNA_pol_phi PF04931.13 OWF55476.1 - 0.098 10.7 0.0 5.9 4.9 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase phi DUF4047 PF13256.6 OWF55476.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) UME PF08064.13 OWF55476.1 - 0.16 11.9 4.0 7.1 6.6 0.0 4.8 6 1 0 6 6 6 0 UME (NUC010) domain Cir_N PF10197.9 OWF55477.1 - 2.8e-13 49.8 0.8 2.8e-13 49.8 0.8 3.5 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 OWF55477.1 - 0.01 15.6 0.2 0.032 14.1 0.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Death PF00531.22 OWF55479.1 - 2.2e-07 30.9 0.5 3.9e-05 23.7 0.2 2.2 2 0 0 2 2 2 2 Death domain Glyco_transf_10 PF00852.19 OWF55480.1 - 2.5e-46 157.6 0.7 2.5e-46 157.6 0.7 1.7 2 1 1 3 3 3 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF55480.1 - 2.8e-18 66.4 0.3 6.5e-18 65.2 0.3 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal UPF0565 PF10561.9 OWF55481.1 - 3.5e-79 266.1 1.4 1.1e-47 162.7 0.2 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 DUF2235 PF09994.9 OWF55481.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) ERCC3_RAD25_C PF16203.5 OWF55482.1 - 4.7e-122 405.9 1.0 7.5e-122 405.3 1.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OWF55482.1 - 6.1e-37 126.6 0.0 1.2e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF55482.1 - 1.6e-14 54.3 0.0 3.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OWF55482.1 - 1e-10 41.9 0.2 2.2e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OWF55482.1 - 0.00096 18.0 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 OWF55482.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3776 PF12618.8 OWF55482.1 - 1.1 9.9 6.7 2.9 8.5 6.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) Glycos_transf_2 PF00535.26 OWF55483.1 - 5e-29 101.3 0.0 9.7e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 OWF55483.1 - 2.7e-18 66.5 0.4 5.7e-18 65.4 0.4 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 OWF55483.1 - 3.9e-06 26.4 0.0 9.2e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 OWF55483.1 - 0.015 14.7 0.0 0.037 13.5 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 GlcNAc PF11397.8 OWF55483.1 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) RicinB_lectin_2 PF14200.6 OWF55483.1 - 0.032 15.0 0.2 0.22 12.3 0.3 2.3 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Proteasome PF00227.26 OWF55484.1 - 1e-42 145.8 0.0 1.2e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Arf PF00025.21 OWF55485.1 - 3.1e-63 212.4 0.7 3.5e-63 212.2 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OWF55485.1 - 1.2e-16 61.0 0.4 1.6e-16 60.6 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF55485.1 - 9.1e-15 54.6 0.2 1.1e-14 54.4 0.2 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OWF55485.1 - 8.3e-13 48.2 0.1 1e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OWF55485.1 - 7.6e-09 35.3 0.2 9.1e-09 35.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OWF55485.1 - 9.1e-09 34.9 1.0 2.5e-05 23.6 0.6 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OWF55485.1 - 7.3e-08 32.5 0.1 1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF55485.1 - 0.002 17.7 0.2 0.026 14.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 OWF55485.1 - 0.02 14.9 0.1 0.048 13.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 OWF55485.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATPase PF06745.13 OWF55485.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 KaiC ABC_tran PF00005.27 OWF55485.1 - 0.14 12.7 0.3 0.23 12.0 0.3 1.3 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 OWF55485.1 - 0.14 11.7 1.1 1.6 8.3 1.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B cNMP_binding PF00027.29 OWF55486.1 - 1.5e-15 57.0 0.1 0.052 13.6 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain His_Phos_2 PF00328.22 OWF55488.1 - 4.7e-29 101.9 0.0 3.9e-23 82.4 0.0 3.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-CDGSH PF09360.10 OWF55489.1 - 1.7e-21 76.2 3.7 5.9e-10 39.2 0.2 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Arm PF00514.23 OWF55490.1 - 7.9e-39 130.5 26.5 2.5e-09 36.9 0.0 9.1 10 0 0 10 10 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OWF55490.1 - 2.4e-15 56.7 13.2 0.0016 18.8 0.9 6.0 1 1 6 7 7 7 6 HEAT repeats Cnd1 PF12717.7 OWF55490.1 - 4.1e-13 49.7 0.5 0.013 15.6 0.2 4.5 1 1 4 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OWF55490.1 - 2.7e-12 45.8 12.2 0.0057 16.8 0.0 7.9 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.6 OWF55490.1 - 6.1e-09 36.2 23.5 0.002 18.6 1.8 6.9 5 3 4 9 9 8 4 HEAT-like repeat DNA_alkylation PF08713.11 OWF55490.1 - 8.9e-09 35.4 0.1 0.37 10.5 0.0 4.2 2 1 0 4 4 4 3 DNA alkylation repair enzyme Adaptin_N PF01602.20 OWF55490.1 - 4.7e-08 32.1 2.1 1.6e-05 23.7 0.4 3.0 1 1 0 2 2 2 2 Adaptin N terminal region CHASE6_C PF17150.4 OWF55490.1 - 2e-07 31.6 0.4 7 7.4 0.0 6.3 6 1 0 6 6 6 1 C-terminal domain of two-partite extracellular sensor domain Proteasom_PSMB PF10508.9 OWF55490.1 - 4.9e-07 28.6 4.1 0.00037 19.1 0.2 3.2 1 1 3 4 4 4 2 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 OWF55490.1 - 0.00074 19.7 0.1 1.6 9.0 0.0 4.0 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_N PF14664.6 OWF55490.1 - 0.00085 18.4 2.6 0.37 9.7 0.3 3.7 1 1 2 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term CLASP_N PF12348.8 OWF55490.1 - 0.001 18.7 0.5 2.7 7.5 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal API5 PF05918.11 OWF55490.1 - 0.0072 15.2 5.0 0.18 10.6 0.6 3.1 2 1 1 3 3 3 2 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 OWF55490.1 - 0.0073 16.5 0.2 0.17 12.1 0.1 3.0 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 OWF55490.1 - 0.0074 16.9 11.1 1.7 9.5 0.1 5.4 5 0 0 5 5 4 2 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 OWF55490.1 - 0.0085 16.2 0.2 3.7 7.7 0.1 3.8 4 0 0 4 4 4 1 V-ATPase subunit H Mo25 PF08569.11 OWF55490.1 - 0.013 14.9 0.2 2 7.7 0.1 2.5 1 1 1 2 2 2 0 Mo25-like Arm_2 PF04826.13 OWF55490.1 - 0.021 14.3 0.4 43 3.4 0.0 3.9 1 1 3 4 4 4 0 Armadillo-like Tim17 PF02466.19 OWF55490.1 - 0.14 12.5 0.0 7.7 6.9 0.0 3.2 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF3731 PF12531.8 OWF55490.1 - 0.35 10.7 5.0 6.6 6.5 0.1 3.4 2 1 0 3 3 3 0 DNA-K related protein XPC-binding PF09280.11 OWF55490.1 - 0.74 9.6 3.8 11 5.8 0.0 4.6 6 0 0 6 6 6 0 XPC-binding domain Chitin_synth_2 PF03142.15 OWF55491.1 - 4.5e-22 78.4 19.7 1.8e-18 66.5 8.0 2.8 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF55491.1 - 1.5e-16 60.9 1.5 1.5e-16 60.9 1.5 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF55491.1 - 2.9e-06 27.3 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OWF55491.1 - 8.2e-06 25.7 0.0 3.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 PPDK_N PF01326.19 OWF55492.1 - 1.3e-79 267.9 0.2 2.1e-79 267.2 0.2 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 OWF55492.1 - 2e-19 69.1 0.0 1.1e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain DUF3326 PF11805.8 OWF55493.1 - 0.092 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) FERM_C PF09380.10 OWF55494.1 - 5.7e-20 71.5 0.0 1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 OWF55494.1 - 3.3e-17 62.2 0.7 1.1e-16 60.4 0.6 1.9 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 OWF55494.1 - 8.4e-17 61.7 0.1 2e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 OWF55494.1 - 1.3e-11 44.3 16.4 6.4e-11 42.2 16.4 2.3 1 0 0 1 1 1 1 FERM adjacent (FA) DUF2796 PF10986.8 OWF55494.1 - 8 6.4 7.1 0.72 9.8 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) LLC1 PF14945.6 OWF55494.1 - 9.7 6.8 11.6 7 7.3 1.9 3.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Peptidase_C2 PF00648.21 OWF55495.1 - 2.6e-87 292.6 0.0 3.7e-87 292.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF55495.1 - 9.9e-27 93.9 0.0 7.3e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 Calpain large subunit, domain III DUF2673 PF10880.8 OWF55496.1 - 0.0023 18.0 20.4 4.1 7.6 0.5 6.5 1 1 6 8 8 8 4 Protein of unknown function (DUF2673) Rap1-DNA-bind PF09197.10 OWF55496.1 - 0.0097 16.5 30.2 5.8 7.6 0.5 9.5 3 2 3 10 10 10 2 Rap1, DNA-binding RicinB_lectin_2 PF14200.6 OWF55496.1 - 0.018 15.8 26.1 5.3 7.8 3.1 5.3 1 1 3 4 4 4 0 Ricin-type beta-trefoil lectin domain-like Methyltransf_9 PF08003.11 OWF55496.1 - 0.092 11.6 0.2 8.3 5.2 0.0 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1698) Peptidase_C2 PF00648.21 OWF55497.1 - 1.7e-79 266.9 0.0 2.3e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF55497.1 - 2.8e-21 76.3 0.0 2.1e-14 53.9 0.0 2.7 2 1 0 2 2 2 2 Calpain large subunit, domain III CYSTM PF12734.7 OWF55498.1 - 0.0002 21.6 4.4 0.0002 21.6 4.4 2.8 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Diphtheria_R PF01324.19 OWF55498.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, R domain Aldo_ket_red PF00248.21 OWF55500.1 - 1.4e-45 155.8 0.0 1.7e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Adipogenin PF15202.6 OWF55501.1 - 3.7e-05 23.7 0.5 13 5.9 0.0 4.9 1 1 4 5 5 5 1 Adipogenin DUF1769 PF08588.10 OWF55501.1 - 0.001 19.2 4.2 36 4.7 0.0 5.2 5 0 0 5 5 5 0 Protein of unknown function (DUF1769) DUF1883 PF08980.10 OWF55501.1 - 0.018 15.0 1.6 58 3.7 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1883) Polo_box_2 PF18531.1 OWF55501.1 - 0.033 14.3 0.0 26 5.0 0.0 3.5 1 1 2 3 3 3 0 Polo box domain Peptidase_M4_C PF02868.15 OWF55501.1 - 0.034 14.0 7.3 0.36 10.7 0.3 2.9 1 1 3 4 4 4 0 Thermolysin metallopeptidase, alpha-helical domain EHN PF06441.12 OWF55501.1 - 0.29 11.5 4.9 4.5 7.7 0.2 3.3 1 1 2 3 3 3 0 Epoxide hydrolase N terminus BAMBI PF06211.12 OWF55502.1 - 2.7e-18 66.2 5.7 6.1e-18 65.0 5.7 1.6 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain CRF-BP PF05428.11 OWF55503.1 - 3.3e-60 203.5 0.2 4e-60 203.2 0.2 1.0 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) CUB PF00431.20 OWF55503.1 - 0.056 13.8 0.3 3.1 8.2 0.0 3.0 2 2 0 2 2 2 0 CUB domain Phage_holin_4_1 PF05105.12 OWF55504.1 - 0.026 14.7 0.2 8.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage holin family betaPIX_CC PF16523.5 OWF55504.1 - 0.47 10.3 4.6 1.2 9.0 2.1 2.6 2 0 0 2 2 2 0 betaPIX coiled coil ABC_membrane PF00664.23 OWF55505.1 - 1e-53 182.8 34.8 1.8e-34 119.7 12.3 3.0 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OWF55505.1 - 7.5e-52 175.5 0.2 6.1e-28 98.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OWF55505.1 - 1.1e-09 38.1 3.4 0.00059 19.3 1.1 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OWF55505.1 - 2.8e-08 33.8 0.2 0.0046 17.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OWF55505.1 - 3.9e-06 27.4 0.1 0.023 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OWF55505.1 - 1.1e-05 25.4 0.5 0.022 14.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OWF55505.1 - 0.00018 21.6 0.1 0.028 14.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 OWF55505.1 - 0.00025 20.7 0.5 0.38 10.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Peptidase_M56 PF05569.11 OWF55505.1 - 0.00086 18.6 3.8 0.00086 18.6 3.8 2.8 3 0 0 3 3 3 1 BlaR1 peptidase M56 AAA_22 PF13401.6 OWF55505.1 - 0.0039 17.5 0.3 5.3 7.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 OWF55505.1 - 0.005 16.2 0.2 0.35 10.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 OWF55505.1 - 0.0062 15.7 0.2 0.74 8.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 OWF55505.1 - 0.0079 16.7 0.1 4.3 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OWF55505.1 - 0.0081 15.9 2.3 1.7 8.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OWF55505.1 - 0.014 15.1 1.5 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_21 PF13304.6 OWF55505.1 - 0.015 15.1 1.5 2 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OWF55505.1 - 0.046 13.8 4.7 1.1 9.2 0.8 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 OWF55505.1 - 0.058 13.0 0.6 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OWF55505.1 - 0.062 13.5 0.1 8.4 6.6 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 OWF55505.1 - 0.073 12.0 0.6 5.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OWF55505.1 - 0.24 11.0 2.2 2.5 7.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LPMO_10 PF03067.15 OWF55507.1 - 1.9e-26 94.0 1.2 1.9e-26 94.0 1.2 2.3 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading RICTOR_phospho PF14665.6 OWF55507.1 - 0.051 13.9 3.1 0.19 12.0 0.4 2.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Pyridoxal_deC PF00282.19 OWF55509.1 - 1.2e-163 544.2 0.0 1.5e-163 543.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OWF55509.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Laminin_EGF PF00053.24 OWF55511.1 - 1e-21 76.8 170.4 0.00062 19.9 16.6 10.7 4 3 5 9 9 9 7 Laminin EGF domain hEGF PF12661.7 OWF55511.1 - 8.9e-09 35.7 51.6 8.3e-05 23.1 6.3 12.7 14 1 1 15 15 15 8 Human growth factor-like EGF EGF_2 PF07974.13 OWF55511.1 - 6.9e-08 32.7 197.8 0.0021 18.4 15.3 13.7 9 5 2 11 11 11 6 EGF-like domain EGF PF00008.27 OWF55511.1 - 0.0062 16.8 13.5 0.0062 16.8 13.5 11.6 12 0 0 12 12 12 5 EGF-like domain DSL PF01414.19 OWF55511.1 - 0.025 14.9 13.1 0.025 14.9 13.1 8.7 7 1 1 8 8 8 0 Delta serrate ligand BTB PF00651.31 OWF55514.1 - 1.4e-28 99.4 0.6 1.5e-26 92.8 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 OWF55514.1 - 1.5e-12 47.5 0.6 2.4e-11 43.7 0.5 2.7 2 1 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF55515.1 - 4.4e-26 91.3 0.0 8.3e-25 87.2 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF55515.1 - 1e-08 35.2 0.8 5.4e-08 32.9 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 OWF55516.1 - 2e-28 98.8 0.8 8.7e-27 93.6 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OWF55516.1 - 7.4e-10 38.9 0.9 7e-09 35.7 0.4 2.7 1 1 1 2 2 2 2 BTB And C-terminal Kelch PHR PF08005.12 OWF55516.1 - 2.1e-06 28.5 0.2 4.8e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 OWF55517.1 - 4.8e-26 91.2 0.2 2.7e-24 85.6 0.0 3.0 2 1 1 3 3 3 1 BTB/POZ domain PHR PF08005.12 OWF55517.1 - 9.3e-16 58.8 0.0 1.9e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 PHR domain BACK PF07707.15 OWF55517.1 - 1.3e-08 34.8 0.9 4.5e-08 33.1 0.5 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch S_layer_N PF05123.12 OWF55517.1 - 0.043 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 S-layer like family, N-terminal region Skp1_POZ PF03931.15 OWF55517.1 - 0.079 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain NAD_binding_6 PF08030.12 OWF55518.1 - 1.7e-29 102.9 0.0 8.3e-29 100.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OWF55518.1 - 1.5e-20 73.3 0.0 4.4e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.32 OWF55518.1 - 1.3e-18 65.0 7.0 1.5e-06 27.3 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF55518.1 - 1.2e-17 62.3 3.9 1.3e-05 24.7 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain Ferric_reduct PF01794.19 OWF55518.1 - 8.8e-17 61.4 12.3 1.7e-16 60.4 12.3 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 OWF55518.1 - 4.1e-12 46.4 6.0 9.2e-09 35.6 0.9 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF55518.1 - 9.1e-12 43.9 9.5 1.2e-05 24.6 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF55518.1 - 2.7e-10 39.9 2.9 0.00091 19.0 0.0 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 OWF55518.1 - 2.1e-05 24.7 0.0 0.00031 21.0 0.0 2.8 1 1 2 3 3 3 2 EF-hand domain FAD_binding_6 PF00970.24 OWF55518.1 - 0.00037 20.8 0.1 0.0028 18.0 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OWF55518.1 - 0.047 14.3 0.0 0.43 11.3 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OWF55519.1 - 5.7e-27 94.8 0.0 1.2e-26 93.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OWF55519.1 - 2.6e-19 69.3 0.0 7.3e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.32 OWF55519.1 - 3.3e-19 66.9 5.8 1.5e-05 24.2 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OWF55519.1 - 1.7e-18 64.9 5.6 3.4e-06 26.6 0.0 5.3 5 0 0 5 5 5 3 EF-hand domain Ferric_reduct PF01794.19 OWF55519.1 - 5.6e-18 65.2 13.7 1.1e-17 64.4 13.7 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 OWF55519.1 - 8.9e-14 51.7 8.0 1.8e-10 41.1 1.3 3.9 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF55519.1 - 9.2e-14 50.2 6.9 0.0012 18.2 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF55519.1 - 1.7e-09 37.3 1.8 0.0011 18.8 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain pair FAD_binding_6 PF00970.24 OWF55519.1 - 0.0023 18.2 0.0 0.006 16.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OWF55519.1 - 0.013 16.2 0.0 0.36 11.5 0.0 3.0 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain EF-hand_9 PF14658.6 OWF55519.1 - 0.017 15.5 0.0 0.68 10.3 0.0 3.1 3 1 0 3 3 3 0 EF-hand domain DIX PF00778.17 OWF55519.1 - 0.018 14.9 0.2 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 DIX domain zf-NADH-PPase PF09297.11 OWF55519.1 - 0.027 14.1 0.9 0.071 12.8 0.9 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Tom5 PF10642.9 OWF55520.1 - 0.00016 21.6 0.3 0.087 12.9 0.1 4.0 3 1 2 5 5 5 2 Mitochondrial import receptor subunit or translocase Toxin_21 PF08091.11 OWF55521.1 - 0.035 14.0 17.8 3.6 7.6 0.4 4.1 2 1 2 4 4 4 0 Spider insecticidal peptide Tom5 PF10642.9 OWF55522.1 - 0.11 12.6 0.1 9 6.4 0.0 3.3 4 1 1 5 5 5 0 Mitochondrial import receptor subunit or translocase Neur_chan_LBD PF02931.23 OWF55523.1 - 2.5e-34 118.6 0.2 3.2e-34 118.3 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain EphA2_TM PF14575.6 OWF55523.1 - 0.038 14.9 0.2 0.17 12.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SmpA_OmlA PF04355.13 OWF55523.1 - 0.04 13.7 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 SmpA / OmlA family Ac76 PF05814.11 OWF55523.1 - 0.23 11.5 3.6 0.31 11.1 0.8 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) PL48 PF15903.5 OWF55524.1 - 1.1e-76 258.1 0.0 4.3e-76 256.1 0.0 1.9 2 0 0 2 2 2 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.6 OWF55524.1 - 0.00067 20.0 0.1 0.014 15.8 0.0 3.1 2 1 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 OWF55524.1 - 0.15 12.6 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 HEAT-like repeat Phage_GP20 PF06810.11 OWF55524.1 - 0.3 10.9 1.0 2.8 7.7 0.0 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 Not3 PF04065.15 OWF55524.1 - 0.7 9.3 2.5 0.99 8.8 0.0 2.3 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Death PF00531.22 OWF55525.1 - 3.7e-09 36.6 0.3 3e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Death domain DDE_Tnp_1_assoc PF13808.6 OWF55525.1 - 0.051 13.6 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-associated Roc PF08477.13 OWF55526.1 - 1.5e-07 31.7 0.0 3.1e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OWF55526.1 - 0.00047 19.8 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Ras family NAPRTase_N PF17767.1 OWF55526.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain CfAFP PF05264.11 OWF55527.1 - 4.4e-06 26.7 0.1 6.7 6.7 0.0 5.6 1 1 6 7 7 7 3 Choristoneura fumiferana antifreeze protein (CfAFP) V-set_2 PF15910.5 OWF55527.1 - 4.4e-05 23.5 0.0 16 5.6 0.0 5.1 1 1 4 6 6 6 2 ICOS V-set domain DUF1853 PF08907.11 OWF55527.1 - 0.86 9.2 4.2 17 5.0 0.6 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF1853) PI-PLC-Y PF00387.19 OWF55528.1 - 0.051 13.9 31.1 10 6.5 0.4 8.7 1 1 7 8 8 8 0 Phosphatidylinositol-specific phospholipase C, Y domain CLU_N PF15044.6 OWF55528.1 - 0.17 12.3 16.5 47 4.4 0.1 8.4 2 2 7 9 9 9 0 Mitochondrial function, CLU-N-term FMO-like PF00743.19 OWF55529.1 - 6.5e-70 236.0 0.1 5.4e-49 167.0 0.1 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF55529.1 - 1.7e-17 63.6 0.1 7.1e-13 48.5 0.2 3.0 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF55529.1 - 1.5e-11 44.1 0.0 1.7e-09 37.4 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF55529.1 - 6.6e-09 35.4 0.0 6.3e-05 22.3 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OWF55529.1 - 5.7e-08 32.7 0.0 0.019 14.6 0.0 3.8 3 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OWF55529.1 - 2.4e-07 30.9 0.1 3.4e-05 24.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OWF55529.1 - 2.1e-06 27.8 0.0 0.0019 18.2 0.0 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OWF55529.1 - 0.0013 19.3 0.0 0.17 12.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OWF55529.1 - 0.0021 17.3 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 OWF55529.1 - 0.04 14.0 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1188 PF06690.11 OWF55529.1 - 0.12 11.8 0.0 0.68 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) CBM_14 PF01607.24 OWF55530.1 - 8e-08 32.3 15.2 0.00043 20.4 4.9 3.6 3 1 0 3 3 3 2 Chitin binding Peritrophin-A domain Mucin PF01456.17 OWF55530.1 - 0.00018 21.5 18.8 0.00039 20.4 18.8 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.11 OWF55530.1 - 0.86 7.7 13.6 1.2 7.2 13.6 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3106 PF11304.8 OWF55533.1 - 0.015 15.8 81.1 14 6.2 1.9 9.9 1 1 13 14 14 14 0 Protein of unknown function (DUF3106) DUF1804 PF08822.11 OWF55533.1 - 1.7 8.6 64.1 15 5.6 0.2 10.7 1 1 16 17 17 17 0 Protein of unknown function (DUF1804) Pkinase PF00069.25 OWF55534.1 - 1.9e-70 237.3 0.0 2.7e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55534.1 - 3.5e-33 115.0 0.0 4.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF55534.1 - 6.9e-08 32.1 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF1127 PF06568.11 OWF55535.1 - 0.034 13.9 15.3 56 3.6 0.0 8.4 10 0 0 10 10 10 0 Domain of unknown function (DUF1127) DUF3663 PF12404.8 OWF55535.1 - 0.28 11.3 4.6 9.5 6.3 0.1 4.2 1 1 4 5 5 5 0 Peptidase Phage_tail_APC PF16778.5 OWF55535.1 - 0.75 9.7 4.6 8.7 6.3 0.5 3.2 2 1 1 3 3 3 0 Phage tail assembly chaperone protein Glycos_transf_1 PF00534.20 OWF55536.1 - 2.4e-39 134.6 0.0 3.7e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OWF55536.1 - 3.2e-17 63.2 0.0 5.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OWF55536.1 - 2.1e-13 50.6 0.0 3.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OWF55536.1 - 2.8e-06 27.9 0.0 4.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OWF55536.1 - 0.00022 21.6 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 WD40 PF00400.32 OWF55537.1 - 1.2e-21 76.6 9.4 0.0004 21.1 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55537.1 - 9e-09 35.5 0.2 0.15 12.4 0.0 5.4 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OWF55537.1 - 0.00031 19.8 0.0 0.067 12.1 0.1 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AF-4 PF05110.13 OWF55537.1 - 0.063 11.4 28.1 0.1 10.7 28.1 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 OWF55537.1 - 0.33 9.4 10.0 0.47 9.0 10.0 1.1 1 0 0 1 1 1 0 Macoilin family DHHW PF14286.6 OWF55537.1 - 1.7 7.9 8.2 2.9 7.1 8.2 1.3 1 0 0 1 1 1 0 DHHW protein CusF_Ec PF11604.8 OWF55538.1 - 0.074 13.0 0.0 41 4.2 0.0 5.0 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF HLH PF00010.26 OWF55539.1 - 3.4e-17 62.1 0.3 5.8e-17 61.4 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 OWF55539.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain WD40 PF00400.32 OWF55540.1 - 6.1e-29 99.7 12.4 1.2e-07 32.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55540.1 - 3.1e-17 62.7 4.7 3.5e-07 30.4 0.5 4.3 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF55540.1 - 2.8e-09 37.2 1.7 0.0071 16.2 0.1 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OWF55540.1 - 0.0018 17.3 0.0 0.13 11.2 0.0 2.7 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 OWF55540.1 - 0.014 14.0 0.7 0.077 11.6 0.0 2.4 3 0 0 3 3 3 0 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 OWF55540.1 - 0.13 10.9 4.7 0.16 10.6 0.2 3.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 FAM183 PF14886.6 OWF55541.1 - 1.5e-33 115.8 2.3 1.8e-33 115.5 2.3 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related Ebp2 PF05890.12 OWF55542.1 - 5.7e-82 275.3 29.1 6.6e-82 275.1 29.1 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PXA PF02194.15 OWF55542.1 - 0.26 11.3 0.7 0.56 10.2 0.7 1.5 1 0 0 1 1 1 0 PXA domain GIY-YIG PF01541.24 OWF55543.1 - 0.045 14.0 0.0 0.064 13.5 0.0 1.4 1 1 0 1 1 1 0 GIY-YIG catalytic domain F5_F8_type_C PF00754.25 OWF55544.1 - 2.3e-09 37.5 2.4 3.7e-09 36.8 2.4 1.3 1 0 0 1 1 1 1 F5/8 type C domain DUF4514 PF14986.6 OWF55544.1 - 0.0051 16.8 0.4 0.011 15.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4514) EphA2_TM PF14575.6 OWF55544.1 - 0.12 13.3 0.0 0.58 11.1 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OWF55544.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protocadherin F5_F8_type_C PF00754.25 OWF55545.1 - 1.5e-08 34.8 0.4 2.6e-08 34.0 0.4 1.3 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 OWF55546.1 - 4e-10 39.9 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Baculo_11_kDa PF06143.11 OWF55546.1 - 0.078 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Aminotran_1_2 PF00155.21 OWF55547.1 - 9.1e-16 58.0 0.0 1.1e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OWF55547.1 - 4.4e-06 25.7 0.0 5.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase CDT1_C PF16679.5 OWF55547.1 - 0.012 16.0 0.1 8.8 6.8 0.0 3.2 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain NUDIX_4 PF14815.6 OWF55548.1 - 1.8e-21 76.2 0.0 4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 OWF55548.1 - 2.9e-21 76.0 0.0 6.2e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OWF55548.1 - 8.7e-09 34.8 0.1 2.1e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 OWF55548.1 - 0.00066 19.9 6.0 0.00066 19.9 6.0 2.1 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III C9orf72-like PF15019.6 OWF55549.1 - 3.2e-27 95.6 0.1 1.1e-13 51.3 0.0 2.4 1 1 1 2 2 2 2 C9orf72-like protein family C9orf72-like PF15019.6 OWF55550.1 - 4e-27 95.3 0.0 7.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 C9orf72-like protein family DSPn PF14671.6 OWF55551.1 - 9.6e-59 197.9 2.6 5e-57 192.3 1.1 3.2 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OWF55551.1 - 2.1e-13 50.3 0.0 6.8e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF55551.1 - 4.6e-05 23.1 0.0 8.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OWF55551.1 - 0.0029 17.7 0.0 0.0084 16.2 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OWF55551.1 - 0.028 14.4 0.1 0.086 12.8 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Pkinase_Tyr PF07714.17 OWF55552.1 - 5.6e-22 78.3 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF55552.1 - 4.3e-20 72.2 0.0 1.2e-19 70.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain OSR1_C PF12202.8 OWF55552.1 - 0.018 15.2 0.3 0.093 13.0 0.0 2.3 2 1 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain PP2C PF00481.21 OWF55553.1 - 2e-70 237.4 13.7 3.4e-57 194.0 0.9 3.3 2 1 0 3 3 3 2 Protein phosphatase 2C SAP130_C PF16014.5 OWF55553.1 - 1.8 7.6 9.9 3.3 6.7 9.9 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Nucleo_P87 PF07267.11 OWF55553.1 - 9 5.0 18.0 15 4.2 18.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 EF-hand_11 PF08976.11 OWF55554.1 - 0.031 15.1 0.1 3.9 8.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Zeta_toxin PF06414.12 OWF55554.1 - 0.04 13.2 0.3 0.11 11.7 0.3 1.7 1 1 0 1 1 1 0 Zeta toxin DUF1953 PF09196.10 OWF55554.1 - 3.3 7.6 6.1 24 4.8 3.0 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1953) Zeta_toxin PF06414.12 OWF55555.1 - 0.0019 17.5 1.7 0.53 9.5 0.2 2.0 1 1 1 2 2 2 2 Zeta toxin MTTB PF06253.11 OWF55555.1 - 0.026 12.5 0.8 0.046 11.7 0.8 1.4 1 1 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) ApbA_C PF08546.11 OWF55555.1 - 0.049 13.8 0.9 0.64 10.2 0.9 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF1889 PF08986.10 OWF55555.1 - 0.22 11.9 2.4 4.2 7.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1889) NPFF PF15085.6 OWF55555.1 - 1.4 9.3 5.7 8.5 6.8 0.5 2.2 1 1 1 2 2 2 0 Neuropeptide FF IF2_N PF04760.15 OWF55555.1 - 4 7.3 8.1 5.8 6.8 0.3 3.2 1 1 2 3 3 3 0 Translation initiation factor IF-2, N-terminal region BAR PF03114.18 OWF55556.1 - 0.068 12.8 0.8 6.1 6.4 0.1 2.0 1 1 1 2 2 2 0 BAR domain Neur_chan_LBD PF02931.23 OWF55557.1 - 2.5e-19 69.6 0.0 3e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain EAGR_box PF16713.5 OWF55557.1 - 0.11 12.2 2.0 0.21 11.3 0.2 2.3 2 0 0 2 2 2 0 Enriched in aromatic and glycine Residues box Pkinase_Tyr PF07714.17 OWF55558.1 - 2.1e-51 174.7 0.0 2.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF55558.1 - 7.4e-22 78.0 0.0 9.2e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OWF55558.1 - 0.0029 16.4 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Death PF00531.22 OWF55559.1 - 3.6e-08 33.5 0.1 1.5e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Death domain COR PF16095.5 OWF55559.1 - 6.1e-08 32.7 0.1 1.3e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain SAND PF01342.21 OWF55561.1 - 1.1e-20 73.1 0.1 2.7e-20 71.9 0.1 1.7 1 0 0 1 1 1 1 SAND domain SAM_1 PF00536.30 OWF55561.1 - 7.5e-08 32.7 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF55561.1 - 1.3e-05 25.2 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_S5 PF00333.20 OWF55562.1 - 1.2e-27 95.6 0.6 1.8e-27 95.1 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OWF55562.1 - 7.9e-10 38.1 0.1 1.4e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Y_phosphatase PF00102.27 OWF55563.1 - 1.6e-34 119.5 0.0 2e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TatD_DNase PF01026.21 OWF55564.1 - 1.2e-09 37.9 0.0 1.4e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase TatD_DNase PF01026.21 OWF55565.1 - 2.8e-19 69.5 0.0 3e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Defensin_3 PF08131.11 OWF55566.1 - 5.2 7.4 7.4 1.2e+02 3.0 0.1 4.0 1 1 0 3 3 3 0 Defensin-like peptide family PGA2 PF07543.12 OWF55567.1 - 0.046 13.7 2.0 0.072 13.1 2.0 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 SNF PF00209.18 OWF55568.1 - 5e-200 665.6 40.5 2.9e-140 468.4 21.2 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family DUF4381 PF14316.6 OWF55568.1 - 0.33 11.2 1.7 7.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TED_complement PF07678.14 OWF55569.1 - 9e-91 304.1 0.0 1.3e-90 303.6 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 OWF55569.1 - 9.4e-30 103.8 0.5 9.9e-28 97.2 0.3 2.9 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 OWF55569.1 - 9.2e-25 86.3 2.1 1.3e-24 85.9 0.5 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 OWF55569.1 - 1.1e-20 74.1 0.1 3.9e-20 72.4 0.1 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 OWF55569.1 - 1.6e-18 66.7 0.1 6.6e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG2 PF01835.19 OWF55569.1 - 3.7e-14 52.9 0.0 3.3e-13 49.9 0.0 2.6 2 0 0 2 2 2 1 MG2 domain MG4 PF17789.1 OWF55569.1 - 1.4e-07 31.5 0.1 0.00038 20.6 0.1 3.3 2 0 0 2 2 2 2 Macroglobulin domain MG4 SQHop_cyclase_C PF13243.6 OWF55569.1 - 1e-05 24.8 0.2 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain MG1 PF17790.1 OWF55569.1 - 0.0013 19.1 0.2 0.0077 16.6 0.0 2.4 2 0 0 2 2 2 1 Macroglobulin domain MG1 Prenyltrans PF00432.21 OWF55569.1 - 0.061 13.1 0.8 13 5.7 0.0 3.4 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat AAA PF00004.29 OWF55570.1 - 5.8e-87 288.8 0.0 2.7e-44 150.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OWF55570.1 - 4e-21 74.5 0.7 1.1e-10 41.1 0.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 OWF55570.1 - 3.7e-09 36.5 0.0 0.0012 18.6 0.0 3.7 5 0 0 5 5 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OWF55570.1 - 2.1e-08 34.5 0.0 0.0018 18.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OWF55570.1 - 1.4e-07 31.6 0.0 0.012 15.6 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OWF55570.1 - 2.9e-07 30.0 0.1 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 OWF55570.1 - 3.4e-07 30.8 2.0 0.0075 16.7 0.6 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 OWF55570.1 - 3.9e-07 30.3 0.0 0.0059 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OWF55570.1 - 1.6e-06 28.4 2.7 0.0018 18.5 1.0 4.0 2 2 1 3 3 3 1 AAA domain Rad17 PF03215.15 OWF55570.1 - 2.6e-06 27.5 0.0 0.036 14.0 0.0 3.2 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_28 PF13521.6 OWF55570.1 - 1.3e-05 25.6 0.0 0.008 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OWF55570.1 - 1.5e-05 24.8 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 OWF55570.1 - 2.1e-05 24.0 1.1 0.043 13.2 0.1 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OWF55570.1 - 6.1e-05 23.1 0.0 0.048 13.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OWF55570.1 - 0.00011 22.2 1.1 0.47 10.4 0.2 3.5 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 OWF55570.1 - 0.00015 22.1 0.0 0.86 10.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 OWF55570.1 - 0.00016 21.2 0.1 0.31 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Bac_DnaA PF00308.18 OWF55570.1 - 0.00033 20.6 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial dnaA protein ABC_tran PF00005.27 OWF55570.1 - 0.00069 20.1 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 OWF55570.1 - 0.00075 20.1 0.0 0.076 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OWF55570.1 - 0.00085 18.6 0.0 0.033 13.3 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 OWF55570.1 - 0.00087 19.3 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OWF55570.1 - 0.0015 18.1 2.1 7.9 6.0 0.1 3.8 3 1 1 4 4 4 0 AAA domain ATPase_2 PF01637.18 OWF55570.1 - 0.0016 18.4 0.1 0.72 9.7 0.0 3.4 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea ATPase PF06745.13 OWF55570.1 - 0.0027 17.1 0.1 0.46 9.8 0.0 2.6 2 1 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 OWF55570.1 - 0.0045 16.7 0.0 1.7 8.3 0.0 3.3 3 1 0 3 3 3 1 Sigma-54 interaction domain ATP-synt_ab PF00006.25 OWF55570.1 - 0.009 15.7 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.11 OWF55570.1 - 0.0095 15.8 0.0 2.4 8.0 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OWF55570.1 - 0.015 15.3 0.0 4.7 7.3 0.1 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 OWF55570.1 - 0.015 15.7 0.0 2.8 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 OWF55570.1 - 0.015 15.0 0.0 0.47 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OWF55570.1 - 0.029 14.3 1.0 0.32 10.9 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase IPT PF01745.16 OWF55570.1 - 0.03 13.7 0.1 0.54 9.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 OWF55570.1 - 0.056 12.7 1.1 5.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin PhoH PF02562.16 OWF55570.1 - 0.076 12.5 0.1 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 OWF55570.1 - 0.082 12.6 0.1 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 OWF55570.1 - 0.09 12.9 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 OWF55570.1 - 0.14 11.6 0.0 3.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein Nup35_RRM_2 PF14605.6 OWF55571.1 - 8.7e-13 48.1 0.1 3e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 OWF55571.1 - 2.1e-05 24.7 0.2 5.8e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 OWF55571.1 - 3.3e-05 23.6 2.0 0.084 12.7 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 OWF55571.1 - 4e-05 23.4 1.5 9.5e-05 22.2 1.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RGS-like PF09128.11 OWF55571.1 - 0.025 14.3 0.0 0.025 14.3 0.0 2.7 3 0 0 3 3 3 0 Regulator of G protein signalling-like domain zf_CCCH_4 PF18345.1 OWF55571.1 - 0.057 13.5 3.0 0.045 13.8 1.2 1.8 2 0 0 2 2 2 0 Zinc finger domain RRM_occluded PF16842.5 OWF55571.1 - 0.059 13.2 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 OWF55571.1 - 0.075 13.1 0.1 0.075 13.1 0.1 2.5 2 0 0 2 2 2 0 RNA binding motif SBF_like PF13593.6 OWF55572.1 - 7.1e-71 239.1 20.5 8.4e-71 238.8 20.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 OWF55572.1 - 6.2e-15 55.4 11.6 6.2e-15 55.4 11.6 2.2 2 1 1 3 3 3 1 Sodium Bile acid symporter family zf-C3HC4_2 PF13923.6 OWF55573.1 - 1.7e-07 30.9 10.8 3e-07 30.2 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF55573.1 - 7e-07 29.0 8.5 1.2e-06 28.2 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF55573.1 - 4.8e-06 26.3 9.1 8.2e-06 25.6 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF55573.1 - 6e-06 26.5 9.5 9.8e-06 25.8 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OWF55573.1 - 0.00019 21.2 8.6 0.00031 20.5 8.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OWF55573.1 - 0.0012 19.1 6.7 0.0024 18.1 6.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain ZapB PF06005.12 OWF55573.1 - 0.0015 18.9 5.0 0.0015 18.9 5.0 3.4 3 0 0 3 3 3 1 Cell division protein ZapB ATG16 PF08614.11 OWF55573.1 - 0.0028 17.9 12.7 0.0099 16.1 12.7 2.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) MIP-T3_C PF17749.1 OWF55573.1 - 0.0056 16.7 3.6 0.018 15.0 3.6 1.9 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region zf-RING_5 PF14634.6 OWF55573.1 - 0.0057 16.6 8.0 0.0096 15.9 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF55573.1 - 0.007 16.4 7.0 0.014 15.4 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger TMF_DNA_bd PF12329.8 OWF55573.1 - 0.01 15.8 0.5 0.01 15.8 0.5 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 OWF55573.1 - 0.029 15.0 0.0 0.029 15.0 0.0 2.4 3 0 0 3 3 1 0 SlyX zf-P11 PF03854.14 OWF55573.1 - 0.043 13.5 6.4 0.087 12.5 6.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger TRAF_BIRC3_bd PF16673.5 OWF55573.1 - 0.053 13.3 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain HALZ PF02183.18 OWF55573.1 - 0.086 13.1 7.4 0.81 10.0 1.0 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper RecC_C PF17946.1 OWF55573.1 - 0.21 11.3 0.2 0.41 10.4 0.2 1.4 1 0 0 1 1 1 0 RecC C-terminal domain YabA PF06156.13 OWF55573.1 - 0.25 12.0 19.9 1.1 10.0 4.0 3.6 1 1 2 3 3 3 0 Initiation control protein YabA DUF4686 PF15742.5 OWF55573.1 - 0.73 8.9 15.7 0.014 14.5 8.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) CENP-H PF05837.12 OWF55573.1 - 0.74 10.2 11.3 1.7 9.1 8.4 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 OWF55573.1 - 0.8 9.8 18.3 3.3 7.8 17.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 OWF55573.1 - 1.2 8.7 4.0 2.5 7.6 4.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1272 PF06906.11 OWF55573.1 - 1.3 9.2 4.1 2.8 8.1 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 OWF55573.1 - 1.4 9.2 9.4 2.9 8.1 9.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OWF55573.1 - 1.4 8.8 7.2 3 7.7 7.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OWF55573.1 - 1.5 8.5 5.3 2.6 7.7 5.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Fez1 PF06818.15 OWF55573.1 - 2 8.8 20.3 0.024 15.1 10.4 2.6 2 1 1 3 3 2 0 Fez1 ABC_tran_CTD PF16326.5 OWF55573.1 - 3.1 8.1 11.3 0.061 13.6 0.7 2.8 3 0 0 3 3 2 0 ABC transporter C-terminal domain DivIC PF04977.15 OWF55573.1 - 4.9 7.0 19.1 4.4 7.1 3.7 3.4 3 0 0 3 3 3 0 Septum formation initiator TMF_TATA_bd PF12325.8 OWF55573.1 - 5.1 7.4 17.3 1.6 9.0 9.2 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.12 OWF55573.1 - 5.5 6.5 11.4 1.1e+02 2.3 11.4 2.4 1 1 0 1 1 1 0 PspA/IM30 family bZIP_1 PF00170.21 OWF55573.1 - 6.4 7.0 19.5 12 6.0 0.5 3.5 3 0 0 3 3 3 0 bZIP transcription factor Sulfotransfer_1 PF00685.27 OWF55574.1 - 3.1e-66 223.6 0.4 4.8e-66 223.0 0.4 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF55574.1 - 7.9e-11 42.7 0.0 2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Nup192 PF11894.8 OWF55575.1 - 0 1169.3 2.6 0 1169.0 2.6 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 OWF55575.1 - 1.8e-06 26.2 0.2 0.0014 16.7 0.0 3.2 3 0 0 3 3 3 3 Nucleoporin subcomplex protein binding to Pom34 Ank_2 PF12796.7 OWF55576.1 - 1.7e-97 320.1 24.6 1e-18 67.7 1.8 8.9 2 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55576.1 - 2.5e-87 286.2 21.5 1e-11 45.1 0.3 11.3 6 4 6 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 OWF55576.1 - 4.2e-81 264.1 20.2 1.2e-07 31.8 0.1 16.9 16 1 0 16 16 16 13 Ankyrin repeat Ank_5 PF13857.6 OWF55576.1 - 7.7e-77 252.4 34.6 5.1e-11 42.6 0.2 13.8 6 3 9 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55576.1 - 2.5e-75 239.4 25.2 1.2e-05 25.3 0.1 18.4 19 0 0 19 19 19 13 Ankyrin repeat Ion_trans PF00520.31 OWF55576.1 - 8.4e-17 61.2 25.4 1.3e-16 60.5 25.4 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OWF55576.1 - 3.2e-05 22.8 14.7 5e-05 22.2 14.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel Vsr PF03852.15 OWF55576.1 - 0.13 12.1 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr TMF_DNA_bd PF12329.8 OWF55576.1 - 0.24 11.4 4.6 0.64 10.1 4.6 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sacchrp_dh_NADP PF03435.18 OWF55576.1 - 0.4 10.9 4.9 1.3 9.3 0.1 3.7 3 1 1 4 4 4 0 Saccharopine dehydrogenase NADP binding domain TMEM190 PF15431.6 OWF55577.1 - 7.7e-14 52.0 197.8 0.4 10.8 3.0 31.0 4 4 44 50 50 50 45 Transmembrane protein 190 Cu-oxidase_3 PF07732.15 OWF55578.1 - 4.3e-26 91.3 0.6 3.4e-25 88.4 0.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OWF55578.1 - 3.3e-22 79.3 0.3 9.7e-22 77.8 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF55578.1 - 9.4e-19 67.5 0.3 8.8e-15 54.6 0.0 4.1 4 1 0 4 4 4 2 Multicopper oxidase PDZ PF00595.24 OWF55580.1 - 2.9e-86 283.9 5.5 2.6e-13 50.1 0.1 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 OWF55580.1 - 2.2e-71 235.6 5.0 5.1e-11 42.2 0.0 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 OWF55580.1 - 3.7e-32 110.5 4.7 0.00015 22.1 0.1 7.3 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.6 OWF55580.1 - 8.1e-10 38.5 3.2 0.5 10.4 0.0 6.5 7 0 0 7 7 7 3 Tricorn protease PDZ domain SAM_Ste50p PF09235.10 OWF55581.1 - 7.1e-11 42.2 0.1 7.9 6.8 0.0 6.2 1 1 8 9 9 9 6 Ste50p, sterile alpha motif RLAN PF14401.6 OWF55581.1 - 5.3e-05 22.9 0.2 58 3.3 0.0 5.9 1 1 4 7 7 7 0 RimK-like ATPgrasp N-terminal domain HHH_3 PF12836.7 OWF55581.1 - 0.00013 22.1 0.1 83 3.6 0.0 6.2 1 1 7 8 8 8 0 Helix-hairpin-helix motif Indigoidine_A PF04227.12 OWF55581.1 - 0.00044 19.7 0.0 38 3.5 0.0 4.8 1 1 4 5 5 5 0 Indigoidine synthase A like protein BACK PF07707.15 OWF55581.1 - 0.0072 16.4 6.0 23 5.2 0.1 4.9 1 1 5 6 6 6 0 BTB And C-terminal Kelch DUF1062 PF06353.12 OWF55581.1 - 0.0084 16.9 0.5 1.2e+02 3.5 0.0 4.2 1 1 5 6 6 6 0 Protein of unknown function (DUF1062) SMG1_N PF17229.2 OWF55581.1 - 0.022 15.4 3.0 1.1e+02 3.6 0.0 4.6 1 1 5 6 6 6 0 Serine/threonine-protein kinase SMG1 N-terminal Tr-sialidase_C PF11052.8 OWF55581.1 - 0.13 12.4 5.4 4e+02 1.3 0.0 7.2 9 0 0 9 9 9 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal DUF4704 PF15787.5 OWF55581.1 - 0.14 11.3 0.6 28 3.8 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4704) RTP1_C1 PF10363.9 OWF55581.1 - 0.15 12.2 0.0 35 4.6 0.0 3.2 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Neugrin PF06413.11 OWF55581.1 - 0.22 11.5 8.1 5.6 6.9 1.8 3.3 1 1 1 2 2 2 0 Neugrin DAGK_cat PF00781.24 OWF55582.1 - 1.2e-26 92.8 0.0 2.2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TPP1 PF10341.9 OWF55583.1 - 1.4e-08 34.7 3.9 0.19 11.7 0.0 5.3 1 1 5 6 6 6 5 Shelterin complex subunit, TPP1/ACD DUF3927 PF13064.6 OWF55583.1 - 0.00055 19.8 24.0 8.7 6.4 0.3 7.7 1 1 8 9 9 9 5 Protein of unknown function (DUF3927) Nrap_D2 PF17403.2 OWF55583.1 - 0.0014 18.4 1.9 3.8 7.3 0.0 4.8 1 1 5 7 7 7 1 Nrap protein PAP/OAS-like domain DUF4975 PF16346.5 OWF55583.1 - 0.036 14.2 0.5 16 5.5 0.0 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4975) RPA_C PF08784.11 OWF55583.1 - 0.074 13.7 0.9 16 6.2 0.0 2.7 1 1 1 2 2 2 0 Replication protein A C terminal NTF-like PF14540.6 OWF55583.1 - 0.1 12.4 0.7 1.4 8.7 0.0 2.7 1 1 0 3 3 3 0 Nucleotidyltransferase-like DUF1844 PF08899.11 OWF55583.1 - 0.34 11.2 3.3 16 5.9 0.1 3.3 1 1 4 5 5 5 0 Domain of unknown function (DUF1844) TPP1 PF10341.9 OWF55584.1 - 4.6e-13 49.1 7.6 0.52 10.3 0.0 8.4 1 1 3 5 5 5 4 Shelterin complex subunit, TPP1/ACD Nrap_D2 PF17403.2 OWF55584.1 - 0.00071 19.4 2.2 8.4 6.1 0.0 5.0 3 2 0 5 5 5 2 Nrap protein PAP/OAS-like domain DUF3927 PF13064.6 OWF55584.1 - 0.011 15.7 40.0 9.1 6.4 0.2 12.1 3 3 11 14 14 14 0 Protein of unknown function (DUF3927) Sec61_beta PF03911.16 OWF55584.1 - 0.018 15.1 3.0 3.6 7.7 0.0 4.4 4 0 0 4 4 4 0 Sec61beta family RPA_C PF08784.11 OWF55584.1 - 0.14 12.8 2.1 1.1e+02 3.6 0.0 4.0 1 1 2 4 4 4 0 Replication protein A C terminal ComX PF05952.12 OWF55584.1 - 0.23 11.4 8.1 19 5.3 0.1 6.0 4 2 2 7 7 7 0 Bacillus competence pheromone ComX Herpes_UL37_2 PF07413.11 OWF55584.1 - 0.47 9.6 12.4 1.6 7.9 1.1 4.5 1 1 3 4 4 4 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF1844 PF08899.11 OWF55584.1 - 0.56 10.6 6.4 14 6.0 0.2 4.7 1 1 3 5 5 5 0 Domain of unknown function (DUF1844) uDENN PF03456.18 OWF55584.1 - 0.78 10.5 1.6 3.7e+02 2.0 0.0 5.7 5 1 1 6 6 6 0 uDENN domain TPP1 PF10341.9 OWF55585.1 - 1.7e-05 24.8 0.7 0.13 12.2 0.7 3.3 1 1 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF3927 PF13064.6 OWF55585.1 - 0.00097 19.1 13.5 2.7 8.0 0.3 5.2 1 1 6 7 7 7 5 Protein of unknown function (DUF3927) Nrap_D2 PF17403.2 OWF55585.1 - 0.0017 18.1 1.0 5.6 6.7 0.1 4.1 1 1 2 4 4 4 1 Nrap protein PAP/OAS-like domain Dexa_ind PF15198.6 OWF55585.1 - 0.14 12.2 3.3 43 4.3 0.1 4.2 1 1 4 5 5 5 0 Dexamethasone-induced Coagulase PF08764.10 OWF55586.1 - 0.02 15.1 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Staphylococcus aureus coagulase RhoGEF PF00621.20 OWF55587.1 - 1.3e-28 100.5 0.0 2.1e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 OWF55587.1 - 7e-09 35.9 4.4 1.4e-08 34.9 0.3 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 OWF55587.1 - 1e-05 26.0 0.2 3.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 OWF55587.1 - 0.00013 21.8 0.9 0.00084 19.2 0.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 OWF55587.1 - 0.0034 17.3 0.1 0.01 15.8 0.1 1.8 1 0 0 1 1 1 1 PH domain DUF1320 PF07030.12 OWF55587.1 - 0.046 13.8 0.2 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) PH_10 PF15411.6 OWF55587.1 - 5.4 7.3 6.3 0.58 10.4 0.3 2.5 3 1 0 3 3 3 0 Pleckstrin homology domain Glyco_hydro_35 PF01301.19 OWF55588.1 - 2.7e-107 359.1 0.0 3.7e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OWF55588.1 - 5.8e-13 48.9 0.0 1.5e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 OWF55588.1 - 6.5e-07 29.9 0.0 0.0055 17.3 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Cellulase PF00150.18 OWF55588.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SGP PF17228.2 OWF55588.1 - 3.8 8.4 6.9 3.9 8.4 2.1 2.4 2 0 0 2 2 2 0 Sulphur globule protein AXH PF08517.12 OWF55589.1 - 5.2e-25 88.3 0.0 1.3e-24 87.0 0.0 1.7 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) zf-C2H2_aberr PF17017.5 OWF55589.1 - 0.0015 18.7 5.9 0.013 15.6 0.1 2.3 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 OWF55589.1 - 0.0033 17.8 12.5 0.06 13.8 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type TDP43_N PF18694.1 OWF55589.1 - 0.22 11.4 0.5 14 5.6 0.0 3.1 2 1 0 3 3 3 0 Transactive response DNA-binding protein N-terminal domain zf-C2H2_4 PF13894.6 OWF55589.1 - 7.1 7.8 19.0 1.4 10.0 3.5 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger WAP PF00095.21 OWF55591.1 - 1.1e-06 28.9 2.5 1.1e-06 28.9 2.5 2.4 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pneumo_att_G PF05539.11 OWF55591.1 - 7.2 6.1 8.7 7.3 6.1 8.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Peptidase_S24 PF00717.23 OWF55592.1 - 0.0018 18.2 12.3 3.8e+02 1.1 12.3 4.2 1 1 0 1 1 1 0 Peptidase S24-like PGDYG PF14083.6 OWF55592.1 - 0.0032 17.7 5.0 0.75 10.1 1.0 3.3 1 1 2 3 3 3 3 PGDYG protein DUF4224 PF13986.6 OWF55592.1 - 0.015 15.2 10.5 31 4.6 0.1 5.7 3 3 4 7 7 7 0 Domain of unknown function (DUF4224) Profilin PF00235.19 OWF55592.1 - 0.018 15.3 2.5 3.6 7.9 0.2 2.3 1 1 1 2 2 2 0 Profilin Lipoprotein_15 PF03640.15 OWF55592.1 - 0.047 13.2 11.0 2.8 7.6 0.2 5.7 4 2 1 7 7 7 0 Secreted repeat of unknown function Adeno_E3A PF05248.12 OWF55592.1 - 0.078 13.0 2.1 12 6.0 0.2 3.2 1 1 2 3 3 3 0 Adenovirus E3A SANTA PF09133.10 OWF55592.1 - 0.19 12.2 4.2 3 8.4 0.4 2.5 1 1 0 2 2 2 0 SANTA (SANT Associated) PixA PF12306.8 OWF55592.1 - 0.22 11.7 2.5 14 5.8 0.1 2.9 1 1 1 3 3 3 0 Inclusion body protein DUF2757 PF10955.8 OWF55592.1 - 0.23 11.7 3.8 49 4.3 0.1 3.8 2 2 1 4 4 4 0 Protein of unknown function (DUF2757) FixG_C PF11614.8 OWF55592.1 - 0.57 10.4 6.5 24 5.1 0.2 3.2 3 0 0 3 3 3 0 IG-like fold at C-terminal of FixG, putative oxidoreductase WAP PF00095.21 OWF55593.1 - 0.00017 21.9 5.8 0.00017 21.9 5.8 1.9 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' LRR_6 PF13516.6 OWF55594.1 - 4.3e-18 63.8 36.9 0.0017 18.2 0.8 14.5 15 0 0 15 15 15 5 Leucine Rich repeat LRR_4 PF12799.7 OWF55594.1 - 2.4e-14 53.2 34.5 0.041 14.3 0.6 9.8 6 1 5 11 11 11 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OWF55594.1 - 8.6e-10 38.4 1.8 3.1e-09 36.6 1.8 2.0 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 OWF55594.1 - 7.1e-07 28.9 26.9 1.2 10.0 0.0 12.7 14 0 0 14 14 14 1 Leucine Rich Repeat F-box PF00646.33 OWF55594.1 - 9.4e-06 25.4 0.6 9.4e-06 25.4 0.6 3.1 4 0 0 4 4 4 1 F-box domain LRR_8 PF13855.6 OWF55594.1 - 0.00032 20.4 15.3 9.6 6.1 0.4 8.0 6 2 3 9 9 9 2 Leucine rich repeat Lsm_C PF14894.6 OWF55594.1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Lsm C-terminal RNA_pol_A_CTD PF03118.15 OWF55594.1 - 0.37 10.6 1.8 5.5 6.8 0.1 3.6 4 0 0 4 4 4 0 Bacterial RNA polymerase, alpha chain C terminal domain SAM_Ste50p PF09235.10 OWF55594.1 - 9.2 6.6 12.6 16 5.9 0.5 4.7 3 2 1 4 4 4 0 Ste50p, sterile alpha motif PQ-loop PF04193.14 OWF55595.1 - 7.2e-25 86.5 7.5 8.6e-16 57.5 2.8 2.8 2 0 0 2 2 2 2 PQ loop repeat Pentapeptide_4 PF13599.6 OWF55596.1 - 7.5e-17 61.3 27.0 1.5 9.0 0.3 11.5 1 1 13 14 14 14 14 Pentapeptide repeats (9 copies) Gal_Lectin PF02140.18 OWF55597.1 - 5.2e-21 74.9 0.3 5.2e-21 74.9 0.3 2.2 2 0 0 2 2 2 1 Galactose binding lectin domain TUSC2 PF15000.6 OWF55599.1 - 2.9e-30 104.8 0.1 3.9e-30 104.4 0.1 1.3 1 1 0 1 1 1 1 Tumour suppressor candidate 2 LRR_8 PF13855.6 OWF55600.1 - 3.4e-53 177.2 56.3 2.3e-16 59.3 4.7 7.1 3 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 OWF55600.1 - 1.1e-23 82.8 38.9 3.4e-06 27.3 2.6 7.2 7 1 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF55600.1 - 1e-19 70.7 0.1 1.5e-09 37.9 0.0 3.6 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF55600.1 - 2e-13 50.2 15.8 0.0003 20.3 0.6 4.0 1 1 3 4 4 4 4 Leucine-rich repeat I-set PF07679.16 OWF55600.1 - 1.4e-12 47.5 0.0 3.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF55600.1 - 1.3e-11 44.9 0.0 3.6e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 OWF55600.1 - 3.5e-10 39.0 38.3 1.1 10.0 0.2 11.8 11 1 0 11 11 11 2 Leucine Rich Repeat ig PF00047.25 OWF55600.1 - 3.7e-10 39.8 0.0 7.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OWF55600.1 - 2.1e-08 34.4 0.0 6.7e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 OWF55600.1 - 1e-06 29.0 0.4 2.7e-06 27.6 0.4 1.7 1 0 0 1 1 1 1 Fibronectin type III domain V-set PF07686.17 OWF55600.1 - 2.1e-05 24.7 0.3 0.00016 21.8 0.1 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRRNT PF01462.18 OWF55600.1 - 0.00013 21.5 1.4 0.0005 19.6 1.4 2.1 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Herpes_gE PF02480.16 OWF55600.1 - 0.026 13.3 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 OWF55600.1 - 0.058 13.6 0.0 1.9 8.7 0.0 2.5 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 tRNA-synt_2b PF00587.25 OWF55601.1 - 1.9e-37 128.9 0.0 3.4e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OWF55601.1 - 6.8e-20 71.3 3.0 6.8e-20 71.3 3.0 3.5 3 1 1 4 4 4 1 Seryl-tRNA synthetase N-terminal domain DDE_5 PF13546.6 OWF55601.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-C2H2 PF00096.26 OWF55602.1 - 1.3e-15 56.9 22.3 7.1e-05 23.0 4.1 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF55602.1 - 1.7e-11 44.0 27.8 2.8e-07 30.7 1.3 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF55602.1 - 5.1e-09 36.2 28.5 0.00052 20.6 3.8 4.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 OWF55602.1 - 7.7e-05 22.9 6.5 0.015 15.7 1.7 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OWF55602.1 - 0.0019 18.4 6.8 0.02 15.2 6.5 2.6 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-BED PF02892.15 OWF55602.1 - 0.0093 16.0 12.6 0.58 10.2 2.2 2.9 2 1 1 3 3 3 2 BED zinc finger zf-C2H2_jaz PF12171.8 OWF55602.1 - 0.011 16.0 8.4 0.28 11.5 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OWF55602.1 - 0.025 15.2 6.7 5.3 7.8 3.6 3.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 OWF55602.1 - 1.2 9.2 25.9 0.051 13.6 5.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf_Hakai PF18408.1 OWF55602.1 - 3.3 7.5 7.9 12 5.8 3.1 2.9 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain UCH PF00443.29 OWF55603.1 - 3.1e-42 144.8 1.1 3.1e-42 144.8 1.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF55603.1 - 1.7e-19 70.6 5.8 2.8e-19 69.9 2.1 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OWF55603.1 - 2.7e-07 30.2 0.0 7.6e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OWF55603.1 - 0.022 15.2 0.0 0.069 13.6 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain DALR_1 PF05746.15 OWF55604.1 - 9.3e-18 64.5 0.0 2.3e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 DALR anticodon binding domain PTN_MK_C PF01091.18 OWF55604.1 - 0.091 13.2 1.8 0.27 11.6 1.8 1.8 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, C-terminal domain Pkinase PF00069.25 OWF55606.1 - 4.1e-68 229.6 0.0 4.7e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55606.1 - 1.4e-27 96.6 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF55606.1 - 0.00045 19.3 0.0 0.0013 17.7 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OWF55606.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF55606.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 OWF55606.1 - 0.1 11.7 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.22 OWF55606.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CBM_14 PF01607.24 OWF55607.1 - 1e-13 51.2 25.9 1.8e-06 28.0 5.6 4.9 4 1 1 5 5 5 3 Chitin binding Peritrophin-A domain EGF PF00008.27 OWF55607.1 - 0.016 15.5 13.1 0.016 15.5 13.1 3.3 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 OWF55607.1 - 0.066 13.9 6.3 0.066 13.9 6.3 3.7 4 0 0 4 4 4 0 Human growth factor-like EGF OmpA_like PF16961.5 OWF55608.1 - 0.0067 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative OmpA-OmpF-like porin family OmpA_like PF16961.5 OWF55609.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family BTB PF00651.31 OWF55610.1 - 1.2e-10 41.6 0.0 3.4e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain MYO10_CC PF16735.5 OWF55610.1 - 0.17 12.0 0.8 0.47 10.6 0.8 1.7 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Ank_2 PF12796.7 OWF55612.1 - 2.4e-20 72.9 12.0 0.0043 17.6 0.1 7.5 4 3 2 7 7 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55612.1 - 6.5e-13 48.9 9.8 0.0034 17.9 0.1 9.0 9 2 1 10 10 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55612.1 - 2.2e-10 39.8 13.8 0.031 14.8 0.1 10.2 12 0 0 12 12 11 2 Ankyrin repeat Ank PF00023.30 OWF55612.1 - 1.5e-05 25.2 3.2 4.5 7.9 0.0 6.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OWF55612.1 - 0.0028 17.9 6.2 21 5.6 0.1 6.8 8 0 0 8 8 7 0 Ankyrin repeats (many copies) Type2_restr_D3 PF16902.5 OWF55612.1 - 0.015 15.2 0.1 2.9 7.9 0.0 2.7 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain AAA_22 PF13401.6 OWF55612.1 - 0.056 13.7 0.2 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OWF55612.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 OWF55612.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C7 PF01830.18 OWF55612.1 - 0.12 11.7 0.5 0.41 10.0 0.5 1.8 1 1 0 1 1 1 0 Peptidase C7 family AAA_5 PF07728.14 OWF55612.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LRR_8 PF13855.6 OWF55613.1 - 8e-81 265.7 84.5 7.4e-16 57.7 9.3 10.6 4 2 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 OWF55613.1 - 3.4e-36 122.7 70.9 6.2e-07 29.7 2.7 10.2 8 1 3 11 11 11 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF55613.1 - 5.4e-33 113.7 16.8 9.8e-08 32.0 0.8 5.5 1 1 5 6 6 6 6 BspA type Leucine rich repeat region (6 copies) 7tm_1 PF00001.21 OWF55613.1 - 2.5e-25 89.3 21.2 4.5e-25 88.5 21.2 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_1 PF00560.33 OWF55613.1 - 5.1e-10 38.5 65.1 1.9 9.4 0.2 16.6 17 0 0 17 17 16 6 Leucine Rich Repeat LRR_6 PF13516.6 OWF55613.1 - 9.4e-08 31.5 80.5 0.49 10.6 0.1 16.4 18 0 0 18 18 17 6 Leucine Rich repeat 7TM_GPCR_Srsx PF10320.9 OWF55613.1 - 9.2e-05 21.9 20.4 0.00011 21.6 19.3 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_9 PF14580.6 OWF55613.1 - 0.00016 21.2 22.6 0.058 12.9 0.8 5.8 2 2 4 7 7 7 4 Leucine-rich repeat 7TM_GPCR_Srw PF10324.9 OWF55613.1 - 0.00022 20.6 11.7 0.0016 17.8 11.7 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Ldl_recept_a PF00057.18 OWF55613.1 - 0.014 15.6 7.9 0.039 14.2 7.9 1.8 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A DUF4064 PF13273.6 OWF55613.1 - 0.029 14.6 10.0 0.051 13.9 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Galactosyl_T PF01762.21 OWF55614.1 - 7.5e-39 133.6 0.1 1.1e-38 133.1 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF55614.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Fringe-like SSF PF00474.17 OWF55615.1 - 2e-118 395.8 20.9 2e-118 395.8 20.9 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family IBV_3C PF03620.13 OWF55615.1 - 0.027 15.0 1.8 0.077 13.5 1.8 1.8 1 0 0 1 1 1 0 IBV 3C protein Nop53 PF07767.11 OWF55615.1 - 0.13 11.6 6.0 0.18 11.2 6.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SSF PF00474.17 OWF55616.1 - 5.8e-56 190.1 5.2 5.8e-56 190.1 5.2 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family FAM176 PF14851.6 OWF55616.1 - 0.01 15.5 0.1 0.028 14.1 0.1 1.7 1 0 0 1 1 1 1 FAM176 family Connexin PF00029.19 OWF55616.1 - 0.015 15.0 0.2 0.057 13.2 0.1 2.1 2 0 0 2 2 2 0 Connexin Smim3 PF17307.2 OWF55616.1 - 0.034 13.7 0.1 0.034 13.7 0.1 2.8 3 0 0 3 3 3 0 Small integral membrane protein 3 LptF_LptG PF03739.14 OWF55616.1 - 0.33 9.8 5.0 0.47 9.2 0.2 3.1 2 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DTHCT PF08070.11 OWF55616.1 - 2.1 9.1 6.5 5 7.9 6.5 1.6 1 1 0 1 1 1 0 DTHCT (NUC029) region RcbX PF02341.15 OWF55617.1 - 1.5e-05 25.3 10.5 51 4.2 0.0 8.2 2 2 8 11 11 11 0 RbcX protein Tachystatin_A PF11406.8 OWF55617.1 - 0.00074 19.5 1.8 87 3.3 0.0 7.0 6 2 2 9 9 9 0 Antimicrobial peptide tachystatin A Herpes_UL3 PF03369.13 OWF55617.1 - 0.29 11.7 6.4 17 5.9 0.2 3.7 1 1 3 4 4 4 0 Herpesvirus UL3 protein CCDC74_C PF14917.6 OWF55617.1 - 1.5 9.4 12.4 27 5.3 1.0 4.7 1 1 3 4 4 4 0 Coiled coil protein 74, C terminal DCP1 PF06058.13 OWF55617.1 - 2.7 7.9 12.7 30 4.6 0.3 5.2 1 1 5 7 7 7 0 Dcp1-like decapping family SSF PF00474.17 OWF55618.1 - 1.4e-122 409.5 21.3 2.5e-122 408.7 21.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family RsgI_N PF12791.7 OWF55618.1 - 1.8e-06 27.8 0.0 20 5.2 0.0 6.8 5 3 2 7 7 7 3 Anti-sigma factor N-terminus Drf_FH1 PF06346.12 OWF55618.1 - 5.3e-05 23.0 12.8 0.024 14.4 3.0 2.9 1 1 0 2 2 2 2 Formin Homology Region 1 IBV_3C PF03620.13 OWF55618.1 - 0.071 13.6 1.1 0.19 12.2 1.1 1.7 1 0 0 1 1 1 0 IBV 3C protein CUB PF00431.20 OWF55619.1 - 5.6e-05 23.5 0.5 7.9e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 CUB domain EphA2_TM PF14575.6 OWF55619.1 - 0.025 15.5 1.7 1.7 9.6 0.6 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 OWF55619.1 - 0.047 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A CYYR1 PF10873.8 OWF55619.1 - 0.07 13.6 0.3 0.48 10.9 0.1 2.0 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 ERGIC_N PF13850.6 OWF55619.1 - 0.17 12.3 1.4 8.1 6.9 0.1 2.6 2 1 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Shisa PF13908.6 OWF55619.1 - 0.26 11.5 6.9 0.098 12.9 1.2 2.2 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 OWF55619.1 - 0.93 10.2 3.8 21 5.8 0.2 2.5 2 1 0 2 2 2 0 WW domain-binding protein 1 CUB PF00431.20 OWF55620.1 - 4.8e-67 223.2 6.1 4.5e-21 75.2 0.0 4.2 4 0 0 4 4 4 4 CUB domain FeoB_associated PF12669.7 OWF55620.1 - 0.15 12.5 5.8 0.44 11.0 5.8 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CUB PF00431.20 OWF55621.1 - 6.6e-73 242.1 4.9 2.4e-22 79.3 0.0 4.1 4 0 0 4 4 4 4 CUB domain DUF5337 PF17272.2 OWF55621.1 - 0.046 13.6 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) CUB PF00431.20 OWF55622.1 - 5e-26 91.2 1.2 8.2e-19 68.0 0.0 2.6 2 0 0 2 2 2 2 CUB domain DUF3377 PF11857.8 OWF55623.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PRCH PF03967.13 OWF55623.1 - 4.4 7.6 8.3 11 6.2 8.3 1.7 1 1 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region SNAP-25 PF00835.19 OWF55625.1 - 0.17 12.2 0.2 12 6.3 0.0 2.4 2 0 0 2 2 2 0 SNAP-25 family TMEM154 PF15102.6 OWF55626.1 - 0.003 17.5 0.1 0.0071 16.3 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF2178 PF09946.9 OWF55626.1 - 0.0099 16.0 0.2 0.025 14.8 0.2 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) Orthoreo_P10 PF07204.11 OWF55626.1 - 0.04 13.9 2.0 0.046 13.7 0.2 2.1 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 OWF55626.1 - 0.075 13.9 0.0 0.18 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF55627.1 - 0.00014 21.8 0.1 0.00014 21.8 0.1 4.9 4 1 2 6 6 4 1 TMEM154 protein family FAM176 PF14851.6 OWF55627.1 - 0.0008 19.1 0.2 0.0008 19.1 0.2 7.4 3 2 4 8 8 7 1 FAM176 family DUF3169 PF11368.8 OWF55627.1 - 0.002 17.7 0.0 0.0051 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Shisa PF13908.6 OWF55627.1 - 0.0087 16.3 0.1 0.0087 16.3 0.1 2.9 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator ASFV_J13L PF05568.11 OWF55627.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 OWF55627.1 - 0.046 14.6 2.2 0.71 10.8 2.1 3.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 OWF55627.1 - 0.099 12.9 0.1 0.099 12.9 0.1 3.1 3 0 0 3 3 3 0 Glycophorin A Hum_adeno_E3A PF05393.11 OWF55627.1 - 0.16 12.0 0.1 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4514 PF14986.6 OWF55627.1 - 0.23 11.4 0.3 0.51 10.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) TMIE PF16038.5 OWF55627.1 - 0.24 11.3 3.7 1.2 9.1 3.7 2.2 1 0 0 1 1 1 0 TMIE protein Baculo_11_kDa PF06143.11 OWF55627.1 - 0.26 10.9 2.6 1.1 8.9 2.6 2.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family GP41 PF00517.17 OWF55627.1 - 2.3 8.1 3.6 0.71 9.7 0.1 1.8 2 0 0 2 2 2 0 Retroviral envelope protein SHP PF03579.13 OWF55627.1 - 3.2 7.8 6.1 6.4 6.8 6.1 1.4 1 0 0 1 1 1 0 Small hydrophobic protein OAD_gamma PF04277.13 OWF55627.1 - 4.3 8.0 0.0 4.3 8.0 0.0 3.9 3 1 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain SID-1_RNA_chan PF13965.6 OWF55627.1 - 8.1 4.7 13.1 74 1.5 13.1 2.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 cNMP_binding PF00027.29 OWF55628.1 - 9.4e-16 57.7 0.8 2.9e-14 52.9 0.0 3.0 4 0 0 4 4 4 1 Cyclic nucleotide-binding domain DUF5589 PF17672.1 OWF55628.1 - 0.0092 15.9 0.0 5.9 6.8 0.0 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5589) DUF5331 PF17265.2 OWF55628.1 - 0.095 12.4 0.3 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5331) CBAH PF02275.18 OWF55629.1 - 1.8e-25 90.3 0.0 8.8e-24 84.7 0.0 2.1 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 OWF55629.1 - 9.7e-14 51.4 0.1 1.8e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HMA PF00403.26 OWF55630.1 - 1.2e-09 38.5 1.4 2.1e-09 37.7 1.4 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain UBA_5 PF16577.5 OWF55631.1 - 1.1e-15 57.5 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 UBA domain ZZ PF00569.17 OWF55631.1 - 1.1e-12 47.6 3.2 2.1e-12 46.7 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 OWF55631.1 - 5.4e-11 42.3 0.0 1.4e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 PB1 domain C1_2 PF03107.16 OWF55631.1 - 0.0053 17.0 3.8 0.011 16.1 3.8 1.5 1 0 0 1 1 1 1 C1 domain zf-UBR PF02207.20 OWF55631.1 - 0.051 13.7 1.4 0.13 12.4 1.4 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) HLH PF00010.26 OWF55632.1 - 8.1e-17 60.9 2.2 8.1e-17 60.9 2.2 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 OWF55632.1 - 0.013 15.9 0.1 0.013 15.9 0.1 2.7 2 0 0 2 2 2 0 Cell division protein ZapB DUF1656 PF07869.12 OWF55632.1 - 3.4 7.7 4.3 23 5.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) ATPase_2 PF01637.18 OWF55633.1 - 0.0068 16.3 0.1 0.0098 15.8 0.1 1.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DED PF01335.21 OWF55633.1 - 0.02 15.2 0.0 0.029 14.7 0.0 1.4 1 1 0 1 1 1 0 Death effector domain Aldo_ket_red PF00248.21 OWF55634.1 - 3.9e-30 105.1 0.0 5.4e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family TPR_10 PF13374.6 OWF55636.1 - 1e-05 25.2 3.5 0.18 11.8 0.1 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 OWF55636.1 - 0.0011 18.8 2.3 6.3 7.1 0.3 4.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OWF55636.1 - 0.0064 16.7 0.9 0.024 14.9 0.9 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF4097 PF13349.6 OWF55637.1 - 6.8e-05 22.3 3.4 0.0004 19.8 3.4 1.8 1 1 0 1 1 1 1 Putative adhesin TPR_10 PF13374.6 OWF55638.1 - 0.00081 19.2 2.9 0.097 12.6 0.8 2.2 1 1 2 3 3 3 3 Tetratricopeptide repeat HEPN_AbiV PF18728.1 OWF55638.1 - 0.01 16.0 0.2 0.039 14.1 0.1 1.9 1 1 1 2 2 2 0 AbiV TPR_7 PF13176.6 OWF55638.1 - 0.026 14.6 1.5 2.8 8.2 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OWF55638.1 - 0.19 12.1 1.4 1.6 9.1 1.4 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Laminin_G_1 PF00054.23 OWF55642.1 - 7e-68 226.9 0.1 4.9e-24 85.0 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 OWF55642.1 - 7e-66 220.5 1.4 1.9e-22 80.1 0.1 3.2 3 0 0 3 3 3 3 Laminin G domain Kazal_2 PF07648.15 OWF55642.1 - 3.3e-40 136.0 73.5 3.9e-11 42.9 5.8 7.9 7 0 0 7 7 7 5 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF55642.1 - 2.5e-29 101.0 64.5 2e-09 37.3 5.5 7.0 5 1 0 5 5 5 5 Kazal-type serine protease inhibitor domain Laminin_EGF PF00053.24 OWF55642.1 - 5.4e-15 55.3 31.1 2.2e-10 40.5 11.3 12.6 11 2 2 13 13 13 2 Laminin EGF domain Laminin_G_3 PF13385.6 OWF55642.1 - 6.6e-14 52.3 0.0 1.1e-05 25.6 0.0 3.5 3 1 1 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 OWF55642.1 - 6.2e-10 39.2 47.4 1.5e-05 25.2 5.0 13.3 12 1 0 12 12 12 5 EGF-like domain Stirrup PF09061.6 OWF55642.1 - 0.07 13.3 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 Stirrup Reg_prop PF07494.11 OWF55642.1 - 0.079 13.2 0.2 1.7 9.1 0.1 3.3 2 0 0 2 2 2 0 Two component regulator propeller SoxZ PF08770.11 OWF55643.1 - 0.00024 20.8 0.0 1.9 8.3 0.0 3.0 1 1 2 3 3 3 3 Sulphur oxidation protein SoxZ ScdA_N PF04405.14 OWF55643.1 - 0.00073 19.1 4.1 2.5 7.8 0.2 4.5 5 0 0 5 5 5 2 Domain of Unknown function (DUF542) Sipho_tail PF05709.11 OWF55643.1 - 0.00098 18.6 0.0 0.61 9.5 0.0 3.0 1 1 0 1 1 1 1 Phage tail protein DpnI_C PF17726.1 OWF55643.1 - 0.023 14.8 5.0 48 4.2 0.1 5.3 1 1 6 7 7 7 0 Dam-replacing HTH domain Sushi PF00084.20 OWF55643.1 - 0.039 14.6 11.4 1.5 9.5 4.3 3.1 1 1 2 3 3 3 0 Sushi repeat (SCR repeat) DUF2527 PF10736.9 OWF55643.1 - 0.74 9.7 15.6 38 4.2 0.1 5.7 2 2 4 6 6 6 0 Protein of unknown function (DUF2627) BNIP3 PF06553.12 OWF55644.1 - 4.3e-29 101.6 5.8 1.8e-28 99.5 5.8 1.8 1 1 0 1 1 1 1 BNIP3 DUF4689 PF15755.5 OWF55644.1 - 0.032 13.9 1.1 0.045 13.4 1.1 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4689) RabGAP-TBC PF00566.18 OWF55645.1 - 0.00015 21.5 0.6 0.0038 16.9 0.1 2.4 1 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF1179 PF06678.11 OWF55645.1 - 4.3 7.4 7.3 2.3 8.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) DUF2054 PF10218.9 OWF55646.1 - 7.7e-43 145.8 20.3 1e-42 145.4 20.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) LydB PF16084.5 OWF55646.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 LydA-holin antagonist BORCS6 PF10157.9 OWF55646.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 p450 PF00067.22 OWF55647.1 - 1.8e-107 360.0 0.0 2e-107 359.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Galactosyl_T PF01762.21 OWF55648.1 - 9.8e-39 133.2 0.0 2e-38 132.2 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase Toxin-JAB1 PF15659.6 OWF55649.1 - 0.018 15.4 0.1 8.9 6.7 0.0 3.3 1 1 3 4 4 4 0 JAB-like toxin 1 MLANA PF14991.6 OWF55650.1 - 1.9 8.8 5.6 1.3 9.4 2.3 2.3 1 1 1 2 2 2 0 Protein melan-A DUF4573 PF15140.6 OWF55651.1 - 5.9e-08 32.7 0.0 0.17 11.7 0.0 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) Amelogenin PF02948.15 OWF55651.1 - 2.9 8.5 13.3 14 6.3 0.6 3.8 1 1 3 4 4 4 0 Amelogenin VWA PF00092.28 OWF55652.1 - 3.4e-29 102.3 0.8 5.1e-29 101.8 0.8 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF55652.1 - 1.7e-12 47.9 2.2 9.2e-12 45.6 0.1 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain CBM_14 PF01607.24 OWF55652.1 - 3.3e-11 43.2 27.8 1.6e-07 31.4 4.7 3.5 2 1 1 3 3 3 3 Chitin binding Peritrophin-A domain Mucin PF01456.17 OWF55652.1 - 0.019 15.0 60.0 0.039 13.9 60.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein PRCC PF10253.9 OWF55652.1 - 0.096 13.5 0.8 0.65 10.8 0.6 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting RIFIN PF02009.16 OWF55652.1 - 0.1 12.5 2.4 0.17 11.8 2.4 1.2 1 0 0 1 1 1 0 Rifin Nucleo_P87 PF07267.11 OWF55652.1 - 0.17 10.7 6.8 0.24 10.2 6.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOG2 PF10428.9 OWF55652.1 - 4.1 6.5 15.7 5.7 6.0 15.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short PF00106.25 OWF55653.1 - 1.7e-20 73.3 0.0 2.2e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OWF55653.1 - 1.6e-14 54.1 0.0 7.8e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF55653.1 - 4.6e-07 29.9 0.0 6.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OWF55653.1 - 0.0011 18.4 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SET PF00856.28 OWF55654.1 - 5.7e-13 49.6 0.4 4.2e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 SET domain HPIH PF13323.6 OWF55654.1 - 0.028 14.3 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain with HPIH motif CYTH PF01928.21 OWF55655.1 - 1.5e-15 57.6 0.1 1.8e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 CYTH domain MBD PF01429.19 OWF55655.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyl-CpG binding domain Na_H_Exchanger PF00999.21 OWF55657.1 - 1.9e-60 204.7 41.4 1.9e-60 204.7 41.4 2.1 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 OWF55657.1 - 2.3e-15 56.4 0.0 2.3e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TF_Zn_Ribbon PF08271.12 OWF55657.1 - 0.065 12.8 1.5 3.4 7.3 0.3 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 OWF55657.1 - 1.4 8.4 3.3 4.5 6.8 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain IgGFc_binding PF17517.2 OWF55658.1 - 1.5e-52 178.7 3.9 3e-52 177.7 3.9 1.5 1 0 0 1 1 1 1 IgGFc binding protein TSP_1 PF00090.19 OWF55658.1 - 3.3e-11 43.2 26.0 1.2e-06 28.6 10.1 2.9 2 1 0 2 2 2 2 Thrombospondin type 1 domain Cu-binding_MopE PF11617.8 OWF55658.1 - 0.00087 19.4 6.0 0.0022 18.1 6.0 1.7 1 0 0 1 1 1 1 Putative metal-binding motif zf-primase PF09329.11 OWF55659.1 - 0.00044 20.0 10.7 9 6.2 0.4 6.3 2 1 6 8 8 8 5 Primase zinc finger Germane PF10646.9 OWF55659.1 - 0.024 15.4 8.1 1.4 9.8 1.8 2.7 1 1 1 2 2 2 0 Sporulation and spore germination Propeptide_C25 PF08126.11 OWF55659.1 - 0.075 12.1 1.2 2.3 7.3 0.2 2.3 1 1 1 2 2 2 0 Propeptide_C25 Plk4_PB1 PF18190.1 OWF55659.1 - 0.15 12.3 1.6 15 5.8 0.1 2.7 1 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 DUF2577 PF10844.8 OWF55661.1 - 1.1 9.5 34.5 25 5.2 8.9 5.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2577) GST_C_6 PF17171.4 OWF55662.1 - 0.044 13.6 4.0 30 4.5 0.0 4.5 3 2 2 5 5 5 0 Glutathione S-transferase, C-terminal domain DUF3649 PF12365.8 OWF55662.1 - 0.41 10.4 4.5 11 5.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) GST_C_6 PF17171.4 OWF55663.1 - 0.0029 17.4 4.2 7.2 6.5 0.1 4.7 1 1 4 5 5 5 1 Glutathione S-transferase, C-terminal domain Pox_D2 PF04701.13 OWF55663.1 - 0.021 15.0 0.8 9.6 6.4 0.2 3.0 1 1 1 2 2 2 0 Pox virus D2 protein Gar1 PF04410.14 OWF55663.1 - 0.074 12.8 0.2 7.1 6.4 0.1 2.6 1 1 2 3 3 3 0 Gar1/Naf1 RNA binding region DUF3764 PF12594.8 OWF55663.1 - 0.17 12.0 3.7 10 6.3 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3764) EF-hand_1 PF00036.32 OWF55664.1 - 1.4e-22 77.5 11.5 1.3e-07 30.7 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OWF55664.1 - 9.5e-21 74.0 5.5 1.2e-13 51.3 5.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF55664.1 - 1.1e-17 63.5 8.2 7.5e-08 32.1 4.4 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF55664.1 - 1.1e-17 62.6 9.5 6e-07 28.7 0.3 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF55664.1 - 2.5e-17 61.3 7.8 1.1e-07 31.2 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF55664.1 - 1.7e-08 34.8 0.4 3.6e-07 30.5 0.3 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF55664.1 - 2.5e-05 24.2 1.9 0.0011 18.9 1.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Excalibur PF05901.11 OWF55664.1 - 0.036 14.7 7.7 0.24 12.0 0.0 3.2 3 0 0 3 3 3 0 Excalibur calcium-binding domain FlaF PF07309.11 OWF55664.1 - 0.038 14.0 0.2 0.054 13.5 0.2 1.2 1 0 0 1 1 1 0 Flagellar protein FlaF Gly_rich_SFCGS PF14272.6 OWF55664.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycine-rich SFCGS TcdB_toxin_midN PF12256.8 OWF55664.1 - 0.17 11.2 2.3 0.73 9.2 0.1 2.3 1 1 2 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Ets PF00178.22 OWF55665.1 - 2.5e-24 85.5 1.3 5.2e-24 84.5 1.3 1.6 1 0 0 1 1 1 1 Ets-domain DUF4960 PF16324.5 OWF55666.1 - 0.004 16.8 1.7 1.2 8.6 0.1 2.7 1 1 2 3 3 3 3 Domain of unknown function (DUF4960) Pentapeptide PF00805.22 OWF55666.1 - 0.025 14.2 3.3 7.3 6.4 0.0 3.2 1 1 3 4 4 4 0 Pentapeptide repeats (8 copies) HigB_toxin PF09907.9 OWF55666.1 - 0.05 13.8 0.9 18 5.6 0.1 3.0 1 1 2 3 3 3 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system GLTSCR1 PF15249.6 OWF55666.1 - 0.11 13.0 3.8 59 4.2 0.2 3.8 1 1 5 6 6 6 0 Conserved region of unknown function on GLTSCR protein Pentapeptide_4 PF13599.6 OWF55666.1 - 0.61 10.3 7.9 0.63 10.2 4.6 2.0 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Cupin_1 PF00190.22 OWF55667.1 - 0.012 15.2 1.5 3 7.5 0.1 3.3 1 1 2 4 4 4 0 Cupin MFS_1 PF07690.16 OWF55668.1 - 1.3e-32 113.1 44.1 5.5e-25 88.0 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF55668.1 - 1.6e-31 109.6 15.6 2.5e-31 109.1 15.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Neurexophilin PF06312.12 OWF55669.1 - 2.2e-09 37.1 0.3 4.2e-09 36.2 0.3 1.4 1 0 0 1 1 1 1 Neurexophilin PC-Esterase PF13839.6 OWF55669.1 - 0.0015 18.4 0.2 0.0038 17.0 0.1 1.7 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Filamin PF00630.19 OWF55669.1 - 0.058 14.2 0.0 0.16 12.8 0.0 1.7 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF3270 PF11674.8 OWF55669.1 - 0.13 12.5 1.0 0.38 11.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Pkinase_Tyr PF07714.17 OWF55670.1 - 1e-69 234.7 0.1 1.5e-69 234.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF55670.1 - 6e-31 107.8 0.1 9.6e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 OWF55670.1 - 0.0019 18.5 2.1 0.0077 16.5 0.1 2.6 2 0 0 2 2 2 1 Fibronectin type III domain Kinase-like PF14531.6 OWF55670.1 - 0.044 13.1 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NAGLU PF05089.12 OWF55671.1 - 1.1e-138 461.7 4.3 1.4e-138 461.4 4.3 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_N PF12971.7 OWF55671.1 - 4.3e-23 80.9 0.0 1.1e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain GBP PF02263.19 OWF55672.1 - 3e-06 26.7 0.0 8.2e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 OWF55672.1 - 5.5e-05 23.2 0.1 0.00081 19.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OWF55672.1 - 8.7e-05 22.6 0.3 8.7e-05 22.6 0.3 3.6 4 1 0 4 4 4 1 Dynamin family AAA_16 PF13191.6 OWF55672.1 - 0.011 16.1 0.0 2.9 8.3 0.0 3.6 3 0 0 3 3 3 0 AAA ATPase domain GRAM PF02893.20 OWF55672.1 - 0.066 13.1 0.0 0.38 10.6 0.0 2.3 1 0 0 1 1 1 0 GRAM domain Phi-29_GP16_7 PF06720.11 OWF55672.1 - 0.45 10.4 3.1 0.34 10.8 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 KELK PF15796.5 OWF55672.1 - 1.7 9.2 12.2 4.2 7.9 1.2 3.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FeoB_N PF02421.18 OWF55672.1 - 2.5 7.6 4.5 5 6.6 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B NAGLU PF05089.12 OWF55673.1 - 5.3e-138 459.5 4.0 8.2e-138 458.9 4.0 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OWF55673.1 - 1.1e-81 274.3 0.1 1.5e-81 273.8 0.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OWF55673.1 - 4.5e-23 80.8 0.0 9.3e-23 79.8 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain zf-B_box PF00643.24 OWF55674.1 - 9.9e-09 35.2 6.2 9.9e-09 35.2 6.2 3.7 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 OWF55674.1 - 1.9e-08 34.0 11.1 1.9e-08 34.0 11.1 4.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF55674.1 - 1.2e-07 31.7 8.3 1.2e-07 31.7 8.3 4.1 2 2 1 3 3 3 1 RING-type zinc-finger NHL PF01436.21 OWF55674.1 - 6.9e-06 25.8 0.2 0.019 15.0 0.0 4.4 4 0 0 4 4 4 1 NHL repeat zf-RING_2 PF13639.6 OWF55674.1 - 4.8e-05 23.6 14.9 4.8e-05 23.6 14.9 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 OWF55674.1 - 0.00024 21.2 13.6 0.00024 21.2 13.6 4.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OWF55674.1 - 0.00033 20.4 13.9 0.00033 20.4 13.9 4.4 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OWF55674.1 - 0.0011 18.7 13.1 0.0011 18.7 13.1 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF55674.1 - 0.0027 17.6 15.4 0.0027 17.6 15.4 3.8 3 0 0 3 3 3 1 zinc-RING finger domain DUF4890 PF16231.5 OWF55674.1 - 8.8 6.9 9.2 6.6 7.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) Pkinase_Tyr PF07714.17 OWF55675.1 - 6.6e-59 199.3 0.1 1e-58 198.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF55675.1 - 2.6e-22 79.5 0.0 4.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 OWF55675.1 - 0.0002 21.7 0.1 0.0006 20.1 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Kinase-like PF14531.6 OWF55675.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YadA_stalk PF05662.14 OWF55676.1 - 0.023 15.0 2.7 1.6 9.2 0.5 2.2 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin DUF3892 PF13031.6 OWF55676.1 - 0.12 13.1 2.6 11 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3892) Pkinase_Tyr PF07714.17 OWF55677.1 - 1.2e-71 241.1 0.2 1.8e-71 240.5 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF55677.1 - 5.8e-31 107.8 0.0 9.3e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 OWF55677.1 - 0.002 18.5 0.2 0.0044 17.3 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Kinase-like PF14531.6 OWF55677.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pur_ac_phosph_N PF16656.5 OWF55677.1 - 0.12 12.9 0.6 0.47 11.1 0.6 2.1 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Pkinase_Tyr PF07714.17 OWF55678.1 - 6.9e-73 245.1 0.1 8.9e-73 244.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF55678.1 - 2.8e-32 112.2 0.0 3.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OWF55678.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like VSP PF03302.13 OWF55678.1 - 0.023 13.6 1.6 0.039 12.8 1.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein MLANA PF14991.6 OWF55678.1 - 0.056 13.7 0.2 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein melan-A Podoplanin PF05808.11 OWF55678.1 - 0.14 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Podoplanin Big_3_2 PF12245.8 OWF55679.1 - 0.08 13.2 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain EutN_CcmL PF03319.13 OWF55680.1 - 0.00019 21.9 10.7 8.1 7.1 0.8 5.2 1 1 4 5 5 5 5 Ethanolamine utilisation protein EutN/carboxysome He_PIG_assoc PF10632.9 OWF55680.1 - 0.00062 19.4 6.2 5.6e+02 0.3 0.0 9.3 12 0 0 12 12 12 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase FG-GAP PF01839.23 OWF55681.1 - 2e-29 101.4 32.8 5.7e-11 42.3 6.6 5.3 5 0 0 5 5 5 4 FG-GAP repeat Zn_dep_PLPC PF00882.18 OWF55681.1 - 5.4e-23 81.9 2.5 1e-22 81.0 2.5 1.5 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 OWF55681.1 - 4.6e-09 36.7 21.1 1.6e-05 25.4 1.5 4.9 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 OWF55681.1 - 0.0019 18.4 8.0 0.11 12.7 0.7 3.9 4 0 0 4 4 4 2 FG-GAP repeat Pkinase PF00069.25 OWF55682.1 - 1.9e-74 250.3 0.0 3.7e-74 249.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55682.1 - 1.4e-37 129.4 0.2 5.8e-37 127.4 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OWF55682.1 - 0.0032 16.5 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF55682.1 - 0.16 11.3 0.2 0.46 9.8 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAO PF01266.24 OWF55683.1 - 1.3e-36 126.9 0.1 5.8e-24 85.3 0.1 2.0 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OWF55683.1 - 0.0016 17.7 0.0 0.004 16.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OWF55683.1 - 0.01 16.1 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF55683.1 - 0.024 13.8 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 OWF55683.1 - 0.054 12.7 0.1 0.092 12.0 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OWF55683.1 - 0.11 11.7 0.3 0.25 10.6 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PAS_11 PF14598.6 OWF55684.1 - 8.5e-17 61.3 2.5 1.4e-16 60.6 0.8 2.1 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 OWF55684.1 - 6.5e-11 42.4 0.2 6.1e-08 32.8 0.1 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 OWF55684.1 - 0.0002 21.2 0.1 0.00068 19.6 0.1 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 OWF55684.1 - 0.00079 19.4 0.2 1.4 8.9 0.1 3.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 OWF55684.1 - 0.004 17.4 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OWF55684.1 - 0.0084 16.4 0.0 4.5 7.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain Lectin_C PF00059.21 OWF55685.1 - 4e-18 66.1 3.7 5.3e-18 65.7 3.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF55685.1 - 9.8e-07 28.6 0.1 1.6e-06 27.9 0.1 1.3 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like DNA_ligase_OB PF03120.16 OWF55686.1 - 0.0056 16.5 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain Transposase_22 PF02994.14 OWF55688.1 - 0.0017 18.5 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 L1 transposable element RBD-like domain DotU PF09850.9 OWF55688.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system protein DotU DSS1_SEM1 PF05160.13 OWF55688.1 - 0.22 11.6 3.7 2.1 8.4 1.7 2.3 2 0 0 2 2 2 0 DSS1/SEM1 family 7tm_1 PF00001.21 OWF55689.1 - 3.4e-27 95.4 7.4 5e-27 94.9 7.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 OWF55689.1 - 7.4e-07 28.8 6.6 9.5e-07 28.4 6.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 OWF55689.1 - 7.9e-05 22.1 8.6 0.00015 21.2 8.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 OWF55689.1 - 0.0011 18.6 8.7 0.0011 18.6 8.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx C_Hendra PF16821.5 OWF55689.1 - 0.14 12.0 0.0 1.4e+02 2.3 0.0 5.6 6 3 0 8 8 8 0 C protein from hendra and measles viruses C4bp_oligo PF18453.1 OWF55690.1 - 1.4e-06 28.4 2.8 29 5.0 0.0 9.1 7 2 3 10 10 10 1 Oligomerization domain of C4b-binding protein alpha ZYG-11_interact PF05884.12 OWF55690.1 - 6.9e-06 25.7 3.0 1.6 8.1 0.1 4.8 1 1 2 5 5 5 3 Interactor of ZYG-11 DUF2671 PF10877.8 OWF55690.1 - 0.0016 18.2 0.0 9.6 6.1 0.0 4.8 3 2 4 7 7 7 1 Protein of unknown function (DUF2671) Saf-Nte_pilin PF09460.10 OWF55690.1 - 0.034 14.2 0.2 14 5.7 0.0 3.3 1 1 2 3 3 3 0 Saf-pilin pilus formation protein Candida_ALS PF05792.13 OWF55690.1 - 0.35 11.5 2.1 1.6e+02 2.9 0.0 3.7 3 0 0 3 3 3 0 Candida agglutinin-like (ALS) Popeye PF04831.13 OWF55690.1 - 0.66 10.1 10.4 2.9 8.1 0.3 3.7 1 1 2 4 4 4 0 Popeye protein conserved region KH_1 PF00013.29 OWF55691.1 - 2.5e-39 132.9 12.9 1.2e-15 57.1 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OWF55691.1 - 1.3e-12 47.4 7.6 1.7e-05 24.5 0.3 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OWF55691.1 - 0.00013 21.8 2.0 0.36 10.7 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 OWF55691.1 - 0.0033 17.5 6.3 0.52 10.4 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain ATPgrasp_YheCD PF14398.6 OWF55691.1 - 7.1 5.8 6.7 0.77 9.0 1.3 2.0 3 0 0 3 3 3 0 YheC/D like ATP-grasp p450 PF00067.22 OWF55692.1 - 1.4e-116 390.0 0.0 1.6e-116 389.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 OWF55693.1 - 1.5e-165 551.6 0.0 1.8e-165 551.4 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OWF55693.1 - 2.3e-23 82.9 0.0 1.4e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF55693.1 - 5.1e-12 45.6 0.0 7e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF55693.1 - 3.5e-11 42.9 0.0 8e-10 38.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OWF55693.1 - 0.00065 19.9 0.1 0.0085 16.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OWF55693.1 - 0.0012 18.9 0.2 0.52 10.4 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OWF55693.1 - 0.0017 18.9 1.1 0.014 15.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OWF55693.1 - 0.021 14.2 0.2 0.046 13.0 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OWF55693.1 - 0.037 14.0 2.9 10 6.1 0.3 3.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OWF55693.1 - 0.045 13.0 0.3 8.2 5.6 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.15 OWF55693.1 - 0.054 12.0 0.0 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.6 OWF55693.1 - 0.078 13.4 0.0 5.8 7.4 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 OWF55693.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Peptidase_M17_N PF02789.17 OWF55693.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain 2-Hacid_dh_C PF02826.19 OWF55693.1 - 0.2 11.0 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 OWF55693.1 - 0.44 10.1 2.4 30 4.1 0.5 3.2 2 1 1 3 3 3 0 FAD dependent oxidoreductase Methyltransf_25 PF13649.6 OWF55694.1 - 8e-05 23.3 0.0 0.00036 21.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF55694.1 - 0.036 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OWF55694.1 - 0.17 12.7 0.0 0.42 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OWF55694.1 - 0.19 11.3 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain p450 PF00067.22 OWF55695.1 - 9.7e-51 172.9 0.0 1.5e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mem_trans PF03547.18 OWF55695.1 - 0.19 10.1 0.0 2.2 6.6 0.0 2.0 2 0 0 2 2 2 0 Membrane transport protein DNA_pol3_tau_5 PF12170.8 OWF55696.1 - 0.00025 21.1 4.5 0.39 10.8 0.2 3.4 1 1 2 3 3 3 2 DNA polymerase III tau subunit V interacting with alpha Channel_Tsx PF03502.13 OWF55696.1 - 0.0092 15.7 0.7 0.31 10.7 0.8 2.5 1 1 0 1 1 1 1 Nucleoside-specific channel-forming protein, Tsx MAPKK1_Int PF08923.10 OWF55696.1 - 3.8 7.3 17.6 0.66 9.8 3.6 3.2 1 1 2 3 3 3 0 Mitogen-activated protein kinase kinase 1 interacting DNA_pol3_tau_5 PF12170.8 OWF55697.1 - 0.0015 18.6 8.8 4.9 7.2 0.1 5.1 1 1 5 6 6 6 2 DNA polymerase III tau subunit V interacting with alpha TyrRSs_C PF16714.5 OWF55697.1 - 0.0021 17.9 2.3 2.7 7.8 0.0 4.0 1 1 2 4 4 4 2 Tyrosyl-tRNA synthetase C-terminal domain Channel_Tsx PF03502.13 OWF55697.1 - 0.006 16.3 0.1 1.3 8.7 0.0 3.0 1 1 0 2 2 2 2 Nucleoside-specific channel-forming protein, Tsx Endonuclease_5 PF04493.14 OWF55697.1 - 1.5 8.5 7.4 8.1 6.1 0.4 3.2 1 1 2 3 3 3 0 Endonuclease V Homeodomain PF00046.29 OWF55698.1 - 3e-22 78.2 7.4 6.1e-22 77.2 6.4 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OWF55698.1 - 0.039 13.9 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF4150 PF13665.6 OWF55699.1 - 9.2e-06 25.8 7.9 1.3 9.2 0.0 4.9 1 1 4 5 5 5 3 Domain of unknown function (DUF4150) ADK_lid PF05191.14 OWF55699.1 - 0.00032 20.6 7.9 13 5.8 0.1 5.4 5 0 0 5 5 5 3 Adenylate kinase, active site lid Inhibitor_I42 PF09394.10 OWF55699.1 - 0.00076 19.9 3.4 12 6.4 0.0 4.0 1 1 3 4 4 4 3 Chagasin family peptidase inhibitor I42 OprB PF04966.12 OWF55699.1 - 9.5 5.5 10.5 18 4.6 0.1 3.7 1 1 3 4 4 4 0 Carbohydrate-selective porin, OprB family Homeodomain PF00046.29 OWF55700.1 - 4.2e-22 77.7 5.3 6.3e-22 77.2 5.3 1.3 1 0 0 1 1 1 1 Homeodomain NHL PF01436.21 OWF55701.1 - 1e-08 34.8 1.4 0.27 11.3 0.0 4.7 4 0 0 4 4 4 2 NHL repeat zf-C3HC4 PF00097.25 OWF55701.1 - 3.4e-08 33.2 15.4 3.4e-08 33.2 15.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF55701.1 - 5.8e-08 32.9 15.5 5.8e-08 32.9 15.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OWF55701.1 - 3.3e-07 30.2 13.3 3.3e-07 30.2 13.3 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OWF55701.1 - 8.4e-07 29.1 13.9 8.4e-07 29.1 13.9 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OWF55701.1 - 2.5e-05 24.0 12.6 2.5e-05 24.0 12.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF55701.1 - 5.8e-05 23.0 14.9 5.8e-05 23.0 14.9 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF55701.1 - 8.8e-05 22.3 14.8 8.8e-05 22.3 14.8 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OWF55701.1 - 0.0043 17.1 0.0 0.44 10.9 0.0 3.3 3 0 0 3 3 3 1 Two component regulator propeller DUF4573 PF15140.6 OWF55702.1 - 2.3e-05 24.3 2.2 0.004 17.0 0.2 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Glyco_trans_4_3 PF12000.8 OWF55702.1 - 0.0046 16.7 2.6 13 5.4 0.1 3.9 1 1 1 3 3 3 3 Glycosyl transferase family 4 group FAST_2 PF08368.12 OWF55702.1 - 0.016 15.9 6.6 13 6.6 0.2 4.6 1 1 3 4 4 4 0 FAST kinase-like protein, subdomain 2 P2_Phage_GpR PF06891.11 OWF55702.1 - 0.13 12.3 0.3 4.6 7.3 0.3 2.4 1 1 0 1 1 1 0 P2 phage tail completion protein R (GpR) LIM PF00412.22 OWF55704.1 - 1e-06 28.9 8.4 2e-06 27.9 8.4 1.5 1 0 0 1 1 1 1 LIM domain Alpha_TIF PF02232.15 OWF55704.1 - 0.013 14.6 0.0 0.38 9.8 0.0 2.1 1 1 1 2 2 2 0 Alpha trans-inducing protein (Alpha-TIF) DUF442 PF04273.13 OWF55705.1 - 2e-14 53.6 0.0 0.00025 21.1 0.0 3.4 3 0 0 3 3 3 3 Putative phosphatase (DUF442) DSPc PF00782.20 OWF55705.1 - 0.078 12.8 0.3 8.4 6.2 0.0 2.9 3 1 1 4 4 4 0 Dual specificity phosphatase, catalytic domain Spec3 PF15795.5 OWF55706.1 - 3.6e-25 88.3 9.3 5.1e-25 87.8 9.3 1.2 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein DUF442 PF04273.13 OWF55707.1 - 2.9e-14 53.1 0.0 0.00018 21.5 0.0 3.8 3 1 0 3 3 3 3 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 OWF55707.1 - 0.072 13.1 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Spec3 PF15795.5 OWF55708.1 - 1.1e-24 86.7 13.7 1.5e-24 86.4 13.7 1.1 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein DUF3040 PF11239.8 OWF55708.1 - 2.2 8.6 3.9 12 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Spec3 PF15795.5 OWF55709.1 - 6.8e-24 84.2 7.7 1.1e-23 83.5 7.7 1.3 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein FYVE PF01363.21 OWF55709.1 - 3.2e-05 24.0 8.9 3.2e-05 24.0 8.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger DUF1218 PF06749.12 OWF55709.1 - 0.12 12.9 1.5 0.3 11.6 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Siva PF05458.12 OWF55709.1 - 0.14 11.8 4.7 0.1 12.2 2.0 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DUF4551 PF15087.6 OWF55709.1 - 0.4 9.5 1.4 0.61 8.9 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sulfotransfer_1 PF00685.27 OWF55710.1 - 4.5e-12 46.0 5.3 1.2e-11 44.6 5.3 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF55710.1 - 3.3e-10 40.7 0.0 1.3e-09 38.8 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF55711.1 - 4.2e-20 72.3 0.1 7e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF55711.1 - 2.3e-15 57.6 0.0 4.7e-15 56.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 OWF55712.1 - 2.5e-08 34.6 0.0 6e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OWF55712.1 - 9.4e-08 31.9 0.1 6.8e-07 29.0 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 OWF55713.1 - 1.2e-09 38.0 1.1 1.7e-09 37.5 1.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF55713.1 - 4.9e-07 30.3 0.1 7.9e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family Nab6_mRNP_bdg PF10567.9 OWF55713.1 - 0.012 15.1 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 RNA-recognition motif zf-C4pol PF14260.6 OWF55713.1 - 0.64 10.5 3.6 0.59 10.6 0.5 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Sulfotransfer_1 PF00685.27 OWF55714.1 - 1.5e-15 57.4 0.7 3.8e-15 56.1 0.7 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF55714.1 - 8.4e-15 55.7 0.1 1.2e-14 55.2 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF4537 PF15057.6 OWF55714.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) PhoR PF11808.8 OWF55715.1 - 0.2 12.1 0.0 0.34 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR CARD PF00619.21 OWF55716.1 - 1.1e-07 31.7 0.3 1.1e-07 31.7 0.3 2.8 3 0 0 3 3 3 1 Caspase recruitment domain TPR_MLP1_2 PF07926.12 OWF55716.1 - 0.00015 21.8 6.4 0.00015 21.8 6.4 3.6 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein HALZ PF02183.18 OWF55716.1 - 0.0014 18.8 2.3 0.0014 18.8 2.3 4.7 5 0 0 5 5 4 2 Homeobox associated leucine zipper CARD_2 PF16739.5 OWF55716.1 - 0.0026 17.7 0.2 0.011 15.7 0.2 2.1 1 0 0 1 1 1 1 Caspase recruitment domain CALCOCO1 PF07888.11 OWF55716.1 - 0.004 16.1 30.1 0.0074 15.2 30.1 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_II PF06009.12 OWF55716.1 - 0.0055 16.7 2.8 0.0055 16.7 2.8 2.4 1 1 1 2 2 2 1 Laminin Domain II Bap31_Bap29_C PF18035.1 OWF55716.1 - 0.018 15.0 6.4 0.018 15.0 6.4 3.4 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain ArsR PF09824.9 OWF55716.1 - 0.023 14.3 0.6 0.023 14.3 0.6 2.1 2 0 0 2 2 2 0 ArsR transcriptional regulator LPD5 PF18799.1 OWF55716.1 - 0.092 13.2 20.4 0.1 13.0 11.0 2.8 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 5 GAS PF13851.6 OWF55716.1 - 0.12 11.7 40.7 0.18 11.1 20.8 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 OWF55716.1 - 0.23 11.5 34.4 0.041 14.0 11.7 3.4 2 2 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.8 OWF55716.1 - 0.38 10.0 28.3 1.1 8.6 7.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) UvrA_DNA-bind PF17755.1 OWF55716.1 - 0.57 10.6 6.5 0.08 13.3 1.5 2.1 2 0 0 2 2 1 0 UvrA DNA-binding domain DUF1664 PF07889.12 OWF55716.1 - 0.88 9.6 15.5 1.3 9.1 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 OWF55716.1 - 2.5 8.6 45.8 0.17 12.3 3.0 4.8 1 1 3 4 4 3 0 Cell division protein ZapB SPATA24 PF15175.6 OWF55716.1 - 2.8 7.8 31.8 0.97 9.3 11.3 2.4 1 1 0 2 2 2 0 Spermatogenesis-associated protein 24 Macoilin PF09726.9 OWF55716.1 - 3.4 6.1 32.5 15 4.0 32.4 2.2 1 1 0 1 1 1 0 Macoilin family DHR10 PF18595.1 OWF55716.1 - 3.7 7.6 37.9 7 6.7 12.9 2.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4686 PF15742.5 OWF55716.1 - 4.4 6.3 48.2 1.6 7.8 19.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4686) HemX PF04375.14 OWF55716.1 - 4.9 6.4 26.7 1.4 8.1 10.1 2.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 OWF55717.1 - 0.00067 19.0 13.2 0.019 14.2 5.4 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) CARD PF00619.21 OWF55717.1 - 0.00079 19.4 0.1 0.0021 18.0 0.1 1.8 1 0 0 1 1 1 1 Caspase recruitment domain HALZ PF02183.18 OWF55717.1 - 0.002 18.3 20.5 0.013 15.7 3.0 3.8 3 1 1 4 4 3 2 Homeobox associated leucine zipper CARD_2 PF16739.5 OWF55717.1 - 0.0027 17.6 0.0 0.0068 16.4 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain ApoO PF09769.9 OWF55717.1 - 0.014 15.4 0.6 0.52 10.3 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein O ZapB PF06005.12 OWF55717.1 - 0.017 15.6 6.4 0.017 15.6 6.4 3.4 2 1 1 3 3 2 0 Cell division protein ZapB DUF4407 PF14362.6 OWF55717.1 - 0.027 13.8 7.9 0.073 12.4 7.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1877 PF08974.10 OWF55717.1 - 0.051 13.7 1.1 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) FapA PF03961.13 OWF55717.1 - 0.11 11.1 14.2 0.33 9.5 9.9 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A LPP PF04728.13 OWF55717.1 - 0.11 12.9 3.8 10 6.6 1.8 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Jnk-SapK_ap_N PF09744.9 OWF55717.1 - 0.11 12.7 25.6 0.22 11.8 9.8 3.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 OWF55717.1 - 0.12 12.5 14.4 0.69 10.1 5.1 3.5 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Exonuc_VII_L PF02601.15 OWF55717.1 - 0.17 11.4 8.5 0.033 13.8 4.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4600 PF15372.6 OWF55717.1 - 0.18 12.3 10.5 3.6 8.0 10.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.22 OWF55717.1 - 0.18 12.1 12.0 1.5 9.0 0.2 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.8 OWF55717.1 - 0.22 9.0 15.9 0.019 12.5 11.5 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Nup88 PF10168.9 OWF55717.1 - 0.48 8.2 13.5 0.71 7.6 13.5 1.1 1 0 0 1 1 1 0 Nuclear pore component HAUS-augmin3 PF14932.6 OWF55717.1 - 0.54 9.8 12.9 1 8.9 11.8 1.9 2 1 0 2 2 1 0 HAUS augmin-like complex subunit 3 bZIP_1 PF00170.21 OWF55717.1 - 0.7 10.0 21.8 0.15 12.2 2.9 3.1 4 0 0 4 4 3 0 bZIP transcription factor AKNA PF12443.8 OWF55717.1 - 0.79 10.4 15.3 0.78 10.4 0.6 3.8 2 1 1 3 3 3 0 AT-hook-containing transcription factor CALCOCO1 PF07888.11 OWF55717.1 - 1.2 7.9 17.1 8.5 5.1 17.6 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_Maf PF03131.17 OWF55717.1 - 1.3 9.6 12.3 1.5 9.4 1.6 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Ax_dynein_light PF10211.9 OWF55717.1 - 1.3 8.9 20.3 0.47 10.4 4.4 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain Bap31_Bap29_C PF18035.1 OWF55717.1 - 1.7 8.7 8.2 0.59 10.2 3.0 2.8 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Golgin_A5 PF09787.9 OWF55717.1 - 1.8 7.9 16.3 0.33 10.4 12.7 1.5 2 0 0 2 2 1 0 Golgin subfamily A member 5 DASH_Spc19 PF08287.11 OWF55717.1 - 2.4 8.0 14.8 1 9.2 8.1 2.6 2 1 1 3 3 2 0 Spc19 CorA PF01544.18 OWF55717.1 - 2.4 7.4 8.6 0.98 8.7 5.1 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 OWF55717.1 - 2.4 8.2 11.7 1.9 8.5 1.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.12 OWF55717.1 - 2.4 8.3 9.0 9.7 6.4 0.7 3.0 1 1 2 3 3 3 0 MbeD/MobD like GAS PF13851.6 OWF55717.1 - 2.5 7.4 24.9 7.4 5.9 0.4 3.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 OWF55717.1 - 3 8.1 15.3 0.89 9.8 4.2 2.7 2 1 0 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF4337 PF14235.6 OWF55717.1 - 3.4 7.8 9.1 6.8 6.8 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) TolA_bind_tri PF16331.5 OWF55717.1 - 3.7 7.7 11.3 0.44 10.7 3.5 3.0 2 1 0 3 3 3 0 TolA binding protein trimerisation Bacillus_HBL PF05791.11 OWF55717.1 - 4.4 7.1 9.9 52 3.6 8.0 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 OWF55717.1 - 4.6 7.3 22.1 0.4 10.8 8.2 2.8 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 OWF55717.1 - 4.8 7.3 20.0 0.63 10.1 6.4 3.2 2 1 2 4 4 3 0 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 OWF55717.1 - 5.5 7.1 21.3 0.45 10.6 2.0 3.0 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 OWF55717.1 - 5.7 5.7 15.9 13 4.5 15.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 OWF55717.1 - 5.8 7.2 13.6 7.2 6.9 4.4 3.3 2 1 2 4 4 4 0 Spc24 subunit of Ndc80 DUF4472 PF14739.6 OWF55717.1 - 6.6 7.5 18.2 2.3 9.0 2.3 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4472) DUF4618 PF15397.6 OWF55717.1 - 7.2 5.9 19.4 0.18 11.2 2.7 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 OWF55717.1 - 9 6.7 11.1 1.4 9.3 1.5 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 OWF55718.1 - 0.0018 18.9 8.3 0.0018 18.9 8.3 5.2 3 2 3 6 6 6 1 SlyX PolyA_pol_RNAbd PF12627.7 OWF55718.1 - 0.071 12.9 0.2 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Lipoprotein_6 PF01441.19 OWF55718.1 - 3.9 7.4 12.1 0.55 10.2 4.6 2.5 1 1 1 2 2 2 0 Lipoprotein Nrf1_DNA-bind PF10491.9 OWF55719.1 - 1.4e-109 364.8 0.2 2.5e-109 363.9 0.2 1.4 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 UK PF02512.14 OWF55719.1 - 0.019 15.4 0.0 0.047 14.2 0.0 1.8 1 0 0 1 1 1 0 Virulence determinant AdoHcyase PF05221.17 OWF55720.1 - 2.1e-120 401.4 0.0 4.5e-66 223.0 0.2 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OWF55720.1 - 8.1e-78 260.1 1.8 1.2e-77 259.5 1.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OWF55720.1 - 1.9e-09 37.1 0.0 4.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OWF55720.1 - 6.3e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 OWF55720.1 - 1.3e-05 24.6 0.5 5e-05 22.7 0.5 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 OWF55720.1 - 0.003 17.8 0.1 0.0068 16.7 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 OWF55720.1 - 0.018 15.5 0.4 0.052 14.0 0.2 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding UPF0180 PF03698.13 OWF55720.1 - 0.031 14.4 0.0 0.96 9.7 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Shikimate_DH PF01488.20 OWF55720.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Oxidored_nitro PF00148.19 OWF55720.1 - 0.049 12.3 0.0 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.21 OWF55720.1 - 0.051 12.9 0.6 0.18 11.1 0.6 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OWF55720.1 - 0.054 12.7 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fusion_gly PF00523.18 OWF55721.1 - 0.034 12.4 0.1 0.043 12.1 0.1 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Sulfotransfer_1 PF00685.27 OWF55722.1 - 5.2e-09 36.0 0.0 5.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain PLU-1 PF08429.11 OWF55723.1 - 3e-101 339.0 18.7 6.9e-99 331.2 6.1 3.4 3 0 0 3 3 3 2 PLU-1-like protein JmjC PF02373.22 OWF55723.1 - 1.9e-42 144.3 1.3 4.7e-42 143.0 1.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 OWF55723.1 - 5.1e-28 96.7 42.7 8.6e-13 48.0 5.1 4.4 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.16 OWF55723.1 - 1.7e-17 63.5 13.1 1.7e-17 63.5 13.1 3.2 2 0 0 2 2 2 1 C5HC2 zinc finger ARID PF01388.21 OWF55723.1 - 1.8e-16 60.6 0.0 4.5e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 OWF55723.1 - 1.3e-15 57.0 0.7 4.7e-15 55.2 0.7 2.0 1 0 0 1 1 1 1 jmjN domain RACo_linker PF17650.1 OWF55723.1 - 0.11 12.4 0.6 4.2 7.3 0.4 3.0 2 0 0 2 2 2 0 RACo linker region GRP PF07172.11 OWF55723.1 - 2.7 8.7 15.0 2.6 8.8 10.0 2.6 2 0 0 2 2 2 0 Glycine rich protein family TPD52 PF04201.15 OWF55724.1 - 0.024 14.2 1.8 0.024 14.2 1.8 3.6 2 1 0 3 3 3 0 Tumour protein D52 family CCDC-167 PF15188.6 OWF55724.1 - 0.035 14.4 0.1 0.035 14.4 0.1 5.5 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Fez1 PF06818.15 OWF55724.1 - 0.18 12.2 44.3 0.93 9.9 19.0 3.4 1 1 2 3 3 3 0 Fez1 Ndc1_Nup PF09531.10 OWF55724.1 - 3.7 6.1 7.1 5.3 5.6 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1664 PF07889.12 OWF55724.1 - 4.3 7.4 21.9 0.54 10.3 0.9 4.5 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Synaptonemal_3 PF15191.6 OWF55725.1 - 0.057 13.2 0.1 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 SCA7 PF08313.12 OWF55726.1 - 1.3e-25 89.1 0.9 2.6e-25 88.1 0.9 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain OrsD PF12013.8 OWF55726.1 - 0.00016 22.1 0.7 0.00045 20.6 0.0 2.1 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D THOC7 PF05615.13 OWF55727.1 - 3.6e-32 111.4 11.9 3.6e-32 111.4 11.9 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 DUF4407 PF14362.6 OWF55727.1 - 0.066 12.6 15.1 0.084 12.2 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S10 PF00450.22 OWF55727.1 - 0.11 11.9 5.7 0.11 11.8 5.7 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase Exonuc_VII_L PF02601.15 OWF55727.1 - 0.36 10.3 11.9 0.42 10.1 11.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_22 PF13401.6 OWF55727.1 - 0.46 10.8 3.1 0.63 10.3 3.1 1.3 1 0 0 1 1 1 0 AAA domain SLATT_fungal PF18142.1 OWF55727.1 - 0.57 10.2 4.2 1.5 8.8 4.0 2.0 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DUF4239 PF14023.6 OWF55727.1 - 0.61 9.8 9.1 0.15 11.7 4.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) DUF3347 PF11827.8 OWF55727.1 - 0.72 10.0 14.6 0.23 11.7 9.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Tmp39 PF10271.9 OWF55727.1 - 0.98 8.3 2.9 1.2 8.1 2.9 1.2 1 0 0 1 1 1 0 Putative transmembrane protein HAUS6_N PF14661.6 OWF55727.1 - 1.2 8.6 21.2 0.39 10.3 11.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Spc7 PF08317.11 OWF55727.1 - 1.5 7.6 21.9 0.29 10.0 10.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 OWF55727.1 - 1.5 9.3 8.9 2.6e+02 2.2 8.5 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 OWF55727.1 - 6.1 7.4 25.5 1.2 9.6 11.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 OWF55727.1 - 6.4 6.8 9.2 12 5.9 8.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 OWF55727.1 - 8 7.0 18.3 15 6.2 10.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Mod_r PF07200.13 OWF55727.1 - 8.2 6.5 23.4 13 5.9 7.4 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.25 OWF55728.1 - 1.6e-32 112.9 0.0 6.3e-32 111.0 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55728.1 - 2.8e-30 105.5 0.0 7e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF55728.1 - 1.9e-06 27.0 0.0 4.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OWF55728.1 - 0.004 16.5 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OWF55728.1 - 0.0041 17.1 1.2 0.035 14.0 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OWF55728.1 - 0.0065 15.5 0.0 0.02 13.8 0.0 1.8 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OWF55728.1 - 0.048 13.0 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-bind_3 PF12776.7 OWF55728.1 - 0.22 12.5 0.6 8.2 7.5 0.2 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF5398 PF17376.2 OWF55728.1 - 0.81 10.3 2.8 11 6.7 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5398) NDUFA12 PF05071.16 OWF55729.1 - 1.8e-31 108.8 3.1 2.2e-31 108.6 3.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ank_2 PF12796.7 OWF55730.1 - 2.9e-31 107.9 1.5 9.6e-13 48.5 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OWF55730.1 - 1.2e-22 79.2 0.7 7.8e-07 29.3 0.1 5.6 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OWF55730.1 - 1.5e-20 73.3 0.2 1.1e-06 29.1 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55730.1 - 1.2e-18 65.2 0.1 1.2e-05 25.3 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF55730.1 - 4.4e-15 55.5 1.2 1.9e-05 24.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 OWF55730.1 - 1.6e-09 38.0 0.1 3.4e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF55730.1 - 5e-08 32.9 0.0 9.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CENP-B_N PF04218.13 OWF55730.1 - 0.15 11.7 0.0 0.48 10.1 0.0 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain wnt PF00110.19 OWF55731.1 - 8e-124 413.2 25.7 9.1e-124 413.0 25.7 1.0 1 0 0 1 1 1 1 wnt family ST7 PF04184.12 OWF55732.1 - 0 1031.2 2.0 0 1031.0 2.0 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 OWF55732.1 - 0.00045 20.7 0.0 0.0024 18.4 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 OWF55732.1 - 0.014 16.1 5.3 2 9.5 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OWF55732.1 - 0.016 15.7 3.7 0.58 10.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 OWF55732.1 - 0.016 15.0 0.1 0.044 13.7 0.1 1.7 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_2 PF07719.17 OWF55732.1 - 0.062 13.4 1.9 0.68 10.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MCM3AP_GANP PF16769.5 OWF55733.1 - 1.8e-119 400.1 1.0 1.8e-119 400.1 1.0 1.4 2 0 0 2 2 2 1 MCM3AP domain of GANP SAC3_GANP PF03399.16 OWF55733.1 - 1.1e-105 353.2 4.8 2e-105 352.4 4.8 1.4 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OWF55733.1 - 8.8e-07 29.0 0.1 1.9e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RRM_1 PF00076.22 OWF55733.1 - 0.023 14.5 0.0 0.075 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CID_GANP PF16766.5 OWF55733.1 - 5.2 7.4 7.6 5.2 7.3 2.2 2.9 1 1 1 2 2 2 0 Binding region of GANP to ENY2 DUF1102 PF06510.11 OWF55734.1 - 0.0025 18.0 23.5 22 5.2 0.1 9.3 8 2 1 11 11 11 5 Protein of unknown function (DUF1102) FLYWCH_u PF16662.5 OWF55735.1 - 0.00043 20.3 13.5 38 4.4 0.3 8.1 1 1 10 11 11 11 3 FLYWCH-type zinc finger-containing protein 1 F-box_4 PF15966.5 OWF55735.1 - 7.1 6.5 13.0 10 6.0 0.4 4.3 1 1 3 4 4 4 0 F-box DAG1 PF05454.11 OWF55736.1 - 5.4e-66 222.9 10.0 4.5e-64 216.6 10.0 2.5 1 1 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) a_DG1_N2 PF18424.1 OWF55736.1 - 1.4e-34 118.8 0.1 8.7e-34 116.3 0.1 2.1 2 0 0 2 2 2 1 Alpha-Dystroglycan N-terminal domain 2 RCR PF12273.8 OWF55736.1 - 9.8e-05 23.0 0.2 9.8e-05 23.0 0.2 3.0 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red He_PIG PF05345.12 OWF55736.1 - 0.00035 20.7 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 Putative Ig domain MLANA PF14991.6 OWF55736.1 - 0.00048 20.4 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 Protein melan-A Sarcoglycan_2 PF05510.13 OWF55736.1 - 0.006 15.4 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 2 Sarcoglycan alpha/epsilon TMEM154 PF15102.6 OWF55736.1 - 0.01 15.7 0.0 0.034 14.0 0.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 OWF55736.1 - 0.041 13.8 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain TPR_1 PF00515.28 OWF55737.1 - 2.6e-18 65.0 0.1 1e-06 28.3 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OWF55737.1 - 1.3e-15 56.2 0.0 0.00041 20.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF55737.1 - 1.8e-12 46.7 0.2 1.8e-05 24.3 0.3 3.2 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 OWF55737.1 - 8.3e-12 45.6 0.2 2.4e-06 28.1 0.0 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OWF55737.1 - 5.9e-11 41.7 0.0 0.023 14.9 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF55737.1 - 8.2e-11 41.8 0.1 8e-05 23.1 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat Cupin_8 PF13621.6 OWF55737.1 - 7.6e-10 38.9 0.6 9.1e-09 35.4 0.0 3.0 2 1 0 2 2 2 1 Cupin-like domain TPR_17 PF13431.6 OWF55737.1 - 1.9e-09 37.3 0.2 0.00061 20.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OWF55737.1 - 1.9e-06 28.3 0.4 0.0022 18.4 0.1 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat SpoIIIAH PF12685.7 OWF55737.1 - 0.00042 20.2 7.7 0.00042 20.2 7.7 1.9 2 0 0 2 2 2 1 SpoIIIAH-like protein Cupin_4 PF08007.12 OWF55737.1 - 0.00044 19.8 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein TPR_12 PF13424.6 OWF55737.1 - 0.00062 20.0 0.0 0.68 10.3 0.1 3.1 1 1 0 2 2 2 1 Tetratricopeptide repeat JmjC PF02373.22 OWF55737.1 - 0.0011 19.4 0.0 0.0045 17.4 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase TPR_7 PF13176.6 OWF55737.1 - 0.012 15.6 0.0 0.96 9.6 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat NARP1 PF12569.8 OWF55737.1 - 0.016 14.1 0.8 0.82 8.5 0.1 2.5 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF410 PF04190.13 OWF55737.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF410) Cupin_2 PF07883.11 OWF55737.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Cupin domain TPR_9 PF13371.6 OWF55737.1 - 0.073 13.2 0.0 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SID-1_RNA_chan PF13965.6 OWF55737.1 - 0.12 10.8 2.9 0.18 10.2 2.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ANAPC3 PF12895.7 OWF55737.1 - 0.14 12.4 0.1 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Zip PF02535.22 OWF55737.1 - 0.27 10.4 1.0 0.38 9.9 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 OWF55737.1 - 0.42 9.4 16.8 1.1 8.0 16.8 1.7 1 0 0 1 1 1 0 Golgi-body localisation protein domain Shisa PF13908.6 OWF55737.1 - 0.61 10.3 8.7 1.3 9.3 8.7 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RAP1 PF07218.11 OWF55737.1 - 0.65 8.2 24.2 1.1 7.5 24.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pox_F17 PF04767.12 OWF55737.1 - 2.9 8.4 7.4 0.4 11.2 2.9 1.9 2 0 0 2 2 1 0 DNA-binding 11 kDa phosphoprotein DUF572 PF04502.13 OWF55737.1 - 3.1 7.3 18.1 2.6 7.6 8.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2448 PF10476.9 OWF55737.1 - 7.7 6.3 8.9 19 5.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function C-terminus (DUF2448) DUF4743 PF15916.5 OWF55738.1 - 6.1e-39 132.7 0.0 8.3e-39 132.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OWF55738.1 - 3e-05 24.1 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-C2H2 PF00096.26 OWF55739.1 - 4.5e-15 55.2 29.2 3.9e-05 23.9 0.6 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF55739.1 - 7.9e-10 38.7 12.8 1e-05 25.7 5.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF55739.1 - 2.8e-08 33.9 24.0 0.019 15.8 5.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger RLL PF10036.9 OWF55739.1 - 0.0045 16.9 2.6 0.0071 16.2 2.6 1.2 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein RNA_pol_3_Rpc31 PF11705.8 OWF55739.1 - 0.027 14.7 10.3 0.05 13.8 10.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OWF55739.1 - 0.084 11.1 7.2 0.1 10.8 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_8 PF15909.5 OWF55739.1 - 0.16 12.3 6.4 0.39 11.1 5.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 OWF55739.1 - 0.2 11.8 9.6 1.8 8.7 0.7 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger SGT1 PF07093.11 OWF55739.1 - 0.2 10.0 4.0 0.26 9.7 4.0 1.1 1 0 0 1 1 1 0 SGT1 protein YL1 PF05764.13 OWF55739.1 - 0.29 11.2 6.3 0.4 10.8 6.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Roughex PF06020.11 OWF55739.1 - 0.32 10.0 5.0 0.45 9.6 5.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PI3K_1B_p101 PF10486.9 OWF55739.1 - 0.33 8.7 3.5 0.45 8.2 3.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FOXP-CC PF16159.5 OWF55739.1 - 0.63 10.7 10.8 3.8 8.2 0.5 3.5 2 1 2 4 4 4 0 FOXP coiled-coil domain Sporozoite_P67 PF05642.11 OWF55739.1 - 0.71 7.9 4.0 0.86 7.6 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 OWF55739.1 - 0.82 9.3 16.5 1.2 8.8 16.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 OWF55739.1 - 2 8.4 9.6 3.5 7.6 9.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal zf-met PF12874.7 OWF55739.1 - 2.5 8.6 14.1 1.9 9.0 0.6 3.0 3 0 0 3 3 2 0 Zinc-finger of C2H2 type DUF2457 PF10446.9 OWF55739.1 - 3.2 6.8 19.4 5.5 6.0 19.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 OWF55739.1 - 3.5 6.9 9.9 4.7 6.4 9.9 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 OWF55739.1 - 7 4.6 18.6 9.5 4.2 18.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 OWF55739.1 - 7 6.3 9.1 3.9 7.1 7.0 1.7 2 0 0 2 2 2 0 FAM176 family Astro_capsid_p PF12226.8 OWF55739.1 - 7.3 5.6 8.8 11 5.1 8.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BRX_assoc PF16627.5 OWF55743.1 - 0.037 14.2 0.5 13 6.0 0.2 2.5 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain Pacifastin_I PF05375.13 OWF55744.1 - 0.02 14.6 7.5 0.02 14.6 7.5 1.8 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) PSP94 PF05825.11 OWF55745.1 - 0.03 14.9 3.1 0.03 14.9 3.1 1.5 1 1 0 1 1 1 0 Beta-microseminoprotein (PSP-94) VWC PF00093.18 OWF55745.1 - 0.086 13.2 7.2 0.37 11.1 7.2 2.0 1 1 0 1 1 1 0 von Willebrand factor type C domain APC_r PF05923.12 OWF55747.1 - 0.52 10.1 11.0 1.6e+02 2.2 0.0 8.4 12 0 0 12 12 12 0 APC repeat Yip1 PF04893.17 OWF55747.1 - 3.2 7.4 34.7 2.9 7.6 1.3 4.7 1 1 1 2 2 2 0 Yip1 domain Band_7 PF01145.25 OWF55749.1 - 1.3e-31 110.0 0.8 1.7e-31 109.6 0.8 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OWF55749.1 - 0.00099 18.9 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 OWF55749.1 - 0.058 13.8 1.2 0.16 12.4 0.5 2.0 1 1 1 2 2 2 0 Phage protein Gp68 RGM_C PF06534.13 OWF55751.1 - 2e-55 187.0 0.0 2.8e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 OWF55751.1 - 5e-43 147.2 1.6 8e-43 146.5 1.6 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus YTV PF07639.11 OWF55753.1 - 1e-09 38.3 138.4 0.98 9.6 5.5 15.5 3 2 16 19 19 19 18 YTV Spp-24 PF07448.11 OWF55753.1 - 0.15 12.3 41.2 52 4.1 0.2 12.7 2 2 16 19 19 19 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Toast_rack_N PF17115.5 OWF55753.1 - 3 8.2 52.5 14 6.0 1.7 8.7 1 1 14 15 15 15 0 N-terminal domain of toast_rack, DUF2154 Paramecium_SA PF01508.16 OWF55755.1 - 2 8.9 8.0 28 5.2 1.4 3.4 2 1 0 3 3 3 0 Paramecium surface antigen domain PG_isomerase_N PF18353.1 OWF55756.1 - 0.11 12.9 1.6 22 5.5 0.1 3.2 1 1 3 4 4 4 0 Phosphoglucose isomerase N-terminal domain Tmemb_cc2 PF10267.9 OWF55756.1 - 0.21 10.7 9.1 2.6 7.1 4.0 2.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Tubulin-binding PF00418.19 OWF55756.1 - 0.38 10.8 19.1 17 5.6 0.0 7.3 9 1 0 9 9 9 0 Tau and MAP protein, tubulin-binding repeat Tetradecapep PF08187.11 OWF55756.1 - 2 8.6 9.9 74 3.7 0.0 6.0 6 2 2 8 8 8 0 Myoactive tetradecapeptides family DUF4573 PF15140.6 OWF55758.1 - 0.041 13.7 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) Sirohm_synth_C PF14823.6 OWF55758.1 - 3.1 7.5 17.0 5.3e+02 0.3 4.2 7.4 1 1 1 2 2 2 0 Sirohaem biosynthesis protein C-terminal Cdc6_C PF09079.11 OWF55759.1 - 0.056 13.4 11.5 3.6 7.6 0.3 4.4 2 1 2 4 4 4 0 CDC6, C terminal winged helix domain Sulfotransfer_1 PF00685.27 OWF55760.1 - 8.3e-62 209.1 2.0 2e-61 207.8 2.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF55760.1 - 3.6e-10 40.6 0.0 3.7e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family DUF5514 PF17633.2 OWF55760.1 - 0.0062 16.8 2.2 0.011 16.0 0.3 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5514) DSPc PF00782.20 OWF55763.1 - 1.4e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OWF55763.1 - 6.8e-06 25.8 0.0 9.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OWF55763.1 - 0.059 13.3 0.7 0.27 11.2 0.2 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family MIR PF02815.19 OWF55765.1 - 1.2e-10 41.6 1.8 1.9e-09 37.6 0.5 2.0 1 1 1 2 2 2 2 MIR domain DUF4530 PF15039.6 OWF55766.1 - 0.0015 18.7 4.2 0.0026 17.9 4.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) LURAP PF14854.6 OWF55766.1 - 0.025 14.5 0.2 0.025 14.5 0.2 3.4 3 1 0 3 3 3 0 Leucine rich adaptor protein Macoilin PF09726.9 OWF55766.1 - 0.039 12.5 13.5 0.062 11.9 13.5 1.2 1 0 0 1 1 1 0 Macoilin family Fringe PF02434.16 OWF55768.1 - 1.2e-12 47.9 2.7 1.1e-11 44.7 2.7 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OWF55768.1 - 4.5e-06 26.6 0.5 0.0019 18.0 0.4 2.3 1 1 1 2 2 2 2 Galactosyltransferase Glyco_transf_21 PF13506.6 OWF55768.1 - 0.057 12.9 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF2950 PF11453.8 OWF55768.1 - 0.15 11.3 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Fringe PF02434.16 OWF55769.1 - 2e-12 47.1 1.8 8.7e-12 45.0 1.1 2.3 1 1 1 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OWF55769.1 - 0.0027 17.5 0.2 0.076 12.8 0.1 2.3 1 1 1 2 2 2 1 Galactosyltransferase DUF3431 PF11913.8 OWF55769.1 - 0.012 15.4 0.3 0.042 13.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3431) DUF4149 PF13664.6 OWF55770.1 - 2.7e-23 82.2 8.5 5.7e-23 81.2 3.6 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4149) Ribosomal_S8e PF01201.22 OWF55771.1 - 2e-53 180.3 1.2 2.5e-53 179.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e LRAT PF04970.13 OWF55771.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF3337 PF11816.8 OWF55772.1 - 7e-45 153.0 0.0 1.1e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OWF55772.1 - 6.3e-29 99.6 12.1 1.8e-05 25.4 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55772.1 - 3.7e-07 30.3 1.3 0.056 13.7 0.0 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAWUL PF16207.5 OWF55772.1 - 0.0005 20.7 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Nucleoporin_N PF08801.11 OWF55772.1 - 0.0017 17.2 1.1 0.54 8.9 0.1 4.0 2 1 2 5 5 5 1 Nup133 N terminal like Nup160 PF11715.8 OWF55772.1 - 0.0018 17.0 5.4 0.95 8.0 0.3 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OWF55772.1 - 0.005 15.9 0.1 1.2 8.1 0.0 2.9 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OWF55772.1 - 0.068 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain Vpu PF00558.19 OWF55773.1 - 5.4 6.9 10.3 4.4 7.1 0.0 2.9 2 1 1 3 3 3 0 Vpu protein Ribosomal_L50 PF10501.9 OWF55774.1 - 1.3e-08 35.0 1.0 2e-08 34.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal subunit 39S Tubulin PF00091.25 OWF55775.1 - 4.6e-53 180.4 0.1 6.8e-53 179.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 OWF55775.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Raco_middle PF17651.1 OWF55775.1 - 0.13 12.0 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 RACo middle region SNF PF00209.18 OWF55776.1 - 7.3e-46 156.9 6.1 8.4e-46 156.7 6.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF55777.1 - 2.9e-79 267.2 22.3 3.4e-79 266.9 22.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF55778.1 - 1.6e-14 53.6 1.3 1.7e-14 53.4 1.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Metallophos PF00149.28 OWF55779.1 - 1.8e-15 58.0 6.8 2.5e-15 57.5 6.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 OWF55780.1 - 3.7e-22 78.7 5.6 5.9e-10 39.6 0.4 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55780.1 - 6.1e-19 68.1 0.1 5.5e-07 30.0 0.0 4.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55780.1 - 2e-15 55.3 0.5 0.0011 19.3 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OWF55780.1 - 2.8e-15 56.2 2.3 5.2e-05 23.5 0.2 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF55780.1 - 6.8e-13 48.4 0.6 0.019 15.4 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Kringle PF00051.18 OWF55781.1 - 2.4e-10 40.6 6.5 2.4e-10 40.6 6.5 1.8 2 1 0 2 2 2 1 Kringle domain NHL PF01436.21 OWF55782.1 - 0.00014 21.7 2.0 1.3 9.2 0.1 4.1 6 0 0 6 6 6 2 NHL repeat SGL PF08450.12 OWF55782.1 - 0.00017 21.3 0.0 0.00095 18.8 0.0 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 OWF55782.1 - 0.0081 16.3 0.4 0.61 10.5 0.0 4.0 5 0 0 5 5 5 1 Two component regulator propeller SdiA-regulated PF06977.11 OWF55782.1 - 0.051 12.8 0.0 2.4 7.3 0.0 2.4 1 1 1 2 2 2 0 SdiA-regulated DUF4655 PF15548.6 OWF55783.1 - 3.8e-07 29.5 0.3 0.043 12.8 0.1 2.9 1 1 2 3 3 3 3 Domain of unknown function (DUF4655) Big_6 PF17936.1 OWF55783.1 - 0.00055 20.2 8.1 6.9 7.0 0.1 4.3 1 1 3 4 4 4 2 Bacterial Ig domain ComP_DUS PF16732.5 OWF55783.1 - 0.0013 19.6 26.4 1.2 10.1 4.6 4.8 1 1 3 4 4 4 3 Type IV minor pilin ComP, DNA uptake sequence receptor NtCtMGAM_N PF16863.5 OWF55783.1 - 0.0033 17.6 15.3 0.077 13.2 3.3 3.6 1 1 2 3 3 3 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF1257 PF06868.11 OWF55783.1 - 0.14 12.4 6.7 0.34 11.2 1.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1257) Methyltrans_RNA PF04452.14 OWF55783.1 - 1.6 8.0 5.2 14 5.0 0.5 3.2 1 1 2 3 3 3 0 RNA methyltransferase Ribosomal_L31 PF01197.18 OWF55783.1 - 7.9 6.8 14.5 1.8e+04 -6.7 14.5 4.8 1 1 0 1 1 1 0 Ribosomal protein L31 STAT_bind PF02864.15 OWF55783.1 - 9.5 6.8 13.2 3.7 8.1 2.0 2.7 1 1 2 3 3 3 0 STAT protein, DNA binding domain Tetraspanin PF00335.20 OWF55784.1 - 3.1e-35 121.9 12.4 3.9e-35 121.6 12.4 1.1 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 OWF55784.1 - 0.0064 16.1 1.4 0.0064 16.1 1.4 2.1 2 0 0 2 2 2 1 SUR7/PalI family ASFV_J13L PF05568.11 OWF55784.1 - 0.013 15.2 0.9 0.37 10.5 0.1 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF2207 PF09972.9 OWF55784.1 - 0.047 12.4 5.6 0.019 13.7 1.4 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YfhO PF09586.10 OWF55784.1 - 0.055 11.7 0.0 0.081 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PspB PF06667.12 OWF55784.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Phage shock protein B WBP-1 PF11669.8 OWF55784.1 - 0.51 11.0 6.3 1.1 9.9 0.7 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 Sigma_reg_N PF13800.6 OWF55784.1 - 3.8 7.9 11.5 0.7 10.2 0.1 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TPR_22 PF18833.1 OWF55791.1 - 0.068 13.3 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Caudal_act PF04731.12 OWF55793.1 - 0.031 14.6 0.5 0.031 14.6 0.5 2.1 1 1 1 2 2 2 0 Caudal like protein activation region ITI_HC_C PF06668.12 OWF55794.1 - 2.1e-13 50.3 0.1 2.5e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.10 OWF55795.1 - 4.1e-25 88.2 0.3 4.1e-25 88.2 0.3 1.9 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain ITI_HC_C PF06668.12 OWF55795.1 - 8.6e-24 84.2 2.2 1.5e-23 83.5 2.2 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VWA PF00092.28 OWF55795.1 - 1.9e-17 64.1 2.0 8.4e-17 62.0 0.6 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 OWF55795.1 - 5e-15 55.8 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OWF55795.1 - 2.5e-09 37.7 0.5 1.2e-08 35.5 0.1 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF3659 PF12396.8 OWF55795.1 - 7.6 6.5 5.9 3.2 7.7 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3659) PX PF00787.24 OWF55796.1 - 2.9e-15 56.2 0.3 7.3e-15 54.9 0.3 1.7 1 0 0 1 1 1 1 PX domain LRR_4 PF12799.7 OWF55796.1 - 3.4e-14 52.7 20.2 3.5e-05 24.1 0.1 5.5 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF55796.1 - 3.5e-10 39.5 12.6 1.9e-06 27.6 1.1 3.3 2 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 OWF55796.1 - 1.5e-08 34.4 4.3 6.4e-06 25.8 0.6 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LZ_Tnp_IS66 PF13007.7 OWF55796.1 - 0.00066 20.4 2.5 2.8 8.8 0.0 4.4 4 0 0 4 4 4 1 Transposase C of IS166 homeodomain LRR_6 PF13516.6 OWF55796.1 - 0.035 14.1 12.1 16 5.8 0.1 6.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 OWF55796.1 - 5.9 7.9 11.0 3.6e+02 2.4 0.2 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat Sulfotransfer_2 PF03567.14 OWF55797.1 - 2.7e-29 102.8 1.8 2.7e-29 102.8 1.8 2.0 2 0 0 2 2 2 1 Sulfotransferase family PRANC PF09372.10 OWF55797.1 - 0.05 13.9 1.1 0.05 13.9 1.1 2.0 2 0 0 2 2 2 0 PRANC domain MMS22L_N PF14910.6 OWF55798.1 - 0.23 9.9 0.0 0.23 9.9 0.0 1.6 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, N-terminal Homeodomain PF00046.29 OWF55799.1 - 1.4e-18 66.4 0.1 2.5e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF55799.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF563 PF04577.14 OWF55801.1 - 9.9e-27 94.4 0.1 1.7e-26 93.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Sulfotransfer_4 PF17784.1 OWF55801.1 - 0.0039 17.1 0.1 0.021 14.6 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain DC_STAMP PF07782.13 OWF55803.1 - 4.3e-49 166.9 2.0 4.3e-49 166.9 2.0 2.2 2 0 0 2 2 2 1 DC-STAMP-like protein SH3_9 PF14604.6 OWF55803.1 - 4.1e-09 36.1 0.0 6.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF55803.1 - 1.1e-07 31.3 0.0 2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF55803.1 - 2.4e-05 23.9 0.1 6.4e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PHF5 PF03660.14 OWF55803.1 - 0.065 13.4 6.1 0.2 11.9 6.1 1.8 1 0 0 1 1 1 0 PHF5-like protein Baculo_PEP_C PF04513.12 OWF55803.1 - 0.22 11.5 2.7 0.65 10.0 0.8 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Astro_capsid_p PF12226.8 OWF55803.1 - 0.46 9.6 7.9 0.79 8.8 7.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SGT1 PF07093.11 OWF55803.1 - 2 6.8 7.1 3.2 6.1 7.1 1.3 1 0 0 1 1 1 0 SGT1 protein Amnionless PF14828.6 OWF55803.1 - 4.5 6.0 9.0 0.75 8.6 3.7 2.4 3 1 0 3 3 3 0 Amnionless Orf78 PF06024.12 OWF55803.1 - 5.6 7.3 8.4 4.5 7.6 1.2 3.5 2 1 0 3 3 3 0 Orf78 (ac78) ABC2_membrane_2 PF12679.7 OWF55803.1 - 8.1 5.6 12.5 0.074 12.3 1.1 2.7 2 1 0 3 3 3 0 ABC-2 family transporter protein Cu-oxidase_3 PF07732.15 OWF55804.1 - 1.6e-39 134.6 2.1 8.9e-38 129.0 0.2 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OWF55804.1 - 1.4e-34 118.7 4.1 7.3e-31 106.7 0.3 4.2 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OWF55804.1 - 9.9e-31 107.0 0.3 1.9e-27 96.3 0.2 3.3 3 1 0 3 3 3 2 Multicopper oxidase DUF4051 PF13260.6 OWF55804.1 - 0.057 13.2 0.7 0.096 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) ORC5_C PF14630.6 OWF55805.1 - 1.5e-64 218.3 0.1 1.9e-64 217.9 0.1 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OWF55805.1 - 4.1e-11 43.6 0.0 1.4e-10 41.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OWF55805.1 - 7.3e-08 32.8 0.0 1.7e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OWF55805.1 - 0.00079 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OWF55805.1 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 OWF55805.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OWF55805.1 - 0.018 15.0 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PIF1 PF05970.14 OWF55805.1 - 0.053 12.7 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 OWF55805.1 - 0.058 13.8 0.7 0.54 10.7 0.1 2.7 3 1 0 3 3 3 0 RNA helicase TniB PF05621.11 OWF55805.1 - 0.073 12.5 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein Viral_helicase1 PF01443.18 OWF55805.1 - 0.11 12.3 0.0 5 6.8 0.0 2.3 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OWF55805.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) L_HMGIC_fpl PF10242.9 OWF55806.1 - 1.5e-49 168.7 10.9 1.8e-49 168.4 10.9 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 OWF55806.1 - 1.4e-07 31.5 6.1 2.7e-07 30.6 6.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family CobS PF02654.15 OWF55806.1 - 0.009 16.2 3.8 0.009 16.2 3.8 1.4 2 0 0 2 2 2 1 Cobalamin-5-phosphate synthase Claudin_2 PF13903.6 OWF55806.1 - 0.38 10.5 12.3 1.6 8.5 12.2 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.23 OWF55806.1 - 0.62 10.1 19.7 7.4 6.6 19.7 2.4 1 1 0 1 1 1 0 Membrane-associating domain DUF2545 PF10810.8 OWF55806.1 - 2.9 8.1 11.1 0.11 12.7 2.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2545) S_4TM PF18159.1 OWF55806.1 - 4.8 6.4 6.1 1.1 8.4 0.5 2.4 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain DUF667 PF05018.13 OWF55807.1 - 2.4e-39 135.0 0.0 3.9e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) OCRE PF17780.1 OWF55807.1 - 0.065 13.3 0.6 0.16 12.0 0.6 1.7 1 0 0 1 1 1 0 OCRE domain TMA7 PF09072.10 OWF55808.1 - 1.2e-23 83.7 24.1 1.3e-23 83.6 24.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 CD225 PF04505.12 OWF55810.1 - 2.9e-09 36.9 0.0 5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF1664 PF07889.12 OWF55812.1 - 0.0089 16.1 0.3 0.022 14.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) STAC2_u1 PF16664.5 OWF55812.1 - 0.01 16.3 0.4 0.017 15.5 0.1 1.6 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Retrotrans_gag PF03732.17 OWF55812.1 - 0.14 12.4 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Eno-Rase_NADH_b PF12242.8 OWF55812.1 - 0.16 11.8 0.3 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gal_Lectin PF02140.18 OWF55813.1 - 2.1e-38 130.6 6.7 1.2e-19 70.5 1.7 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain DUF3395 PF11875.8 OWF55813.1 - 0.065 13.1 0.3 21 5.0 0.0 3.0 3 1 0 4 4 4 0 Domain of unknown function (DUF3395) NCD2 PF04905.13 OWF55813.1 - 0.11 12.5 0.0 10 6.1 0.0 2.1 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Copine PF07002.16 OWF55814.1 - 1.1e-68 230.9 0.0 1.8e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 OWF55814.1 - 3.9e-28 97.7 0.0 4.5e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain Mab-21 PF03281.14 OWF55815.1 - 3e-24 85.8 3.2 4.8e-24 85.2 3.2 1.2 1 0 0 1 1 1 1 Mab-21 protein TPR_7 PF13176.6 OWF55815.1 - 0.0077 16.2 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OWF55815.1 - 0.014 15.6 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OWF55815.1 - 0.018 14.9 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF55815.1 - 0.07 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OWF55815.1 - 0.071 13.3 0.0 21 5.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat S-methyl_trans PF02574.16 OWF55816.1 - 2.7e-28 99.5 0.0 3.5e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase S-methyl_trans PF02574.16 OWF55817.1 - 2.2e-34 119.5 0.1 2.8e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Integrin_B_tail PF07965.12 OWF55818.1 - 5.3e-15 55.7 5.5 5.3e-15 55.7 5.5 3.0 2 1 0 3 3 3 1 Integrin beta tail domain EGF_2 PF07974.13 OWF55818.1 - 5.3e-15 55.5 69.3 4.9e-05 23.6 15.8 5.5 4 1 1 5 5 5 4 EGF-like domain I-EGF_1 PF18372.1 OWF55818.1 - 3.5e-05 23.8 1.4 3.5e-05 23.8 1.4 5.6 5 0 0 5 5 5 4 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 OWF55818.1 - 0.13 12.3 50.8 0.54 10.4 7.8 5.1 4 0 0 4 4 4 0 Tenascin EGF domain p450 PF00067.22 OWF55819.1 - 2.8e-106 356.0 0.0 3.4e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_1 PF00001.21 OWF55820.1 - 3.2e-63 213.5 7.0 5.4e-63 212.8 7.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF55820.1 - 5.9e-13 48.8 15.3 2.8e-06 26.9 10.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF55820.1 - 9.5e-10 38.5 16.6 9.5e-10 38.5 16.6 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF55820.1 - 0.084 12.6 10.7 0.03 14.1 6.5 2.1 2 0 0 2 2 2 0 Olfactory receptor ALMS_repeat PF18727.1 OWF55820.1 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Alstrom syndrome repeat DUF4504 PF14953.6 OWF55821.1 - 3.2e-30 105.4 1.5 6.6e-30 104.4 1.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) Ninjurin PF04923.12 OWF55822.1 - 7.2e-30 103.0 0.5 8.6e-30 102.7 0.5 1.0 1 0 0 1 1 1 1 Ninjurin SLATT_fungal PF18142.1 OWF55822.1 - 0.024 14.6 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DUF2207 PF09972.9 OWF55822.1 - 0.056 12.2 0.2 0.068 11.9 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 OWF55822.1 - 0.097 12.8 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Mab-21 PF03281.14 OWF55824.1 - 1.9e-21 76.6 1.5 6.2e-21 75.0 0.1 2.3 3 0 0 3 3 3 1 Mab-21 protein Baculo_PEP_C PF04513.12 OWF55825.1 - 0.026 14.6 4.6 0.05 13.7 4.6 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5118 PF17162.4 OWF55825.1 - 0.028 14.2 9.5 19 5.1 2.1 4.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5118) FKBP_C PF00254.28 OWF55825.1 - 0.067 13.5 6.7 22 5.5 0.7 3.9 1 1 2 3 3 3 0 FKBP-type peptidyl-prolyl cis-trans isomerase Spidroin_MaSp PF11260.8 OWF55825.1 - 0.36 11.2 5.0 1.2 9.4 4.2 1.9 1 1 0 1 1 1 0 Major ampullate spidroin 1 and 2 DUF3382 PF11862.8 OWF55825.1 - 2.1 8.7 13.6 2.2e+03 -1.0 13.6 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) SLATT_fungal PF18142.1 OWF55825.1 - 4.8 7.2 38.8 32 4.5 12.7 3.7 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Prenylcys_lyase PF07156.14 OWF55825.1 - 9.6 5.2 12.0 55 2.7 12.0 1.9 1 1 0 1 1 1 0 Prenylcysteine lyase TSP_1 PF00090.19 OWF55826.1 - 3.3e-38 129.7 180.5 2.3e-06 27.7 9.4 11.5 9 2 1 11 11 11 10 Thrombospondin type 1 domain DND1_DSRM PF14709.7 OWF55829.1 - 8.6e-15 54.8 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 OWF55829.1 - 6.1e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif G-patch PF01585.23 OWF55829.1 - 8.5e-14 51.2 1.0 1.9e-13 50.1 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OWF55829.1 - 5.8e-05 23.1 2.0 0.00011 22.2 2.0 1.6 1 0 0 1 1 1 1 G-patch domain Ins_P5_2-kin PF06090.12 OWF55830.1 - 0.22 10.9 1.1 11 5.3 1.1 3.3 1 1 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase adh_short_C2 PF13561.6 OWF55831.1 - 8.9e-66 221.8 0.6 1e-65 221.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OWF55831.1 - 2.8e-54 183.6 1.0 3.5e-54 183.2 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OWF55831.1 - 1.6e-12 47.7 0.2 2.3e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OWF55831.1 - 0.071 13.0 1.0 0.35 10.7 0.1 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Snf7 PF03357.21 OWF55832.1 - 1e-41 142.4 20.4 1e-41 142.4 20.4 1.4 2 0 0 2 2 2 1 Snf7 Nuc_deoxyri_tr3 PF11071.8 OWF55832.1 - 0.072 13.1 2.2 0.1 12.6 1.0 1.7 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Apis_Csd PF11671.8 OWF55832.1 - 2.6 8.1 4.5 5.3 7.0 4.5 1.6 1 1 0 1 1 1 0 Complementary sex determiner protein CCDC84 PF14968.6 OWF55832.1 - 2.7 7.5 8.8 3.2 7.3 8.8 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 DUF16 PF01519.16 OWF55832.1 - 2.9 8.4 14.8 33 5.0 11.4 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 LMP PF04778.12 OWF55833.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 LMP repeated region Pkinase_Tyr PF07714.17 OWF55834.1 - 2.1e-93 312.4 0.0 8.6e-92 307.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase fn3 PF00041.21 OWF55834.1 - 9.3e-44 147.7 14.9 6.3e-09 36.1 0.0 7.7 7 0 0 7 7 7 6 Fibronectin type III domain Pkinase PF00069.25 OWF55834.1 - 3.7e-38 131.4 0.0 6.1e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pur_ac_phosph_N PF16656.5 OWF55834.1 - 1.3e-09 38.5 8.2 0.0068 17.0 0.0 5.8 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain PQQ_2 PF13360.6 OWF55834.1 - 0.01 15.4 1.2 0.17 11.4 0.1 2.7 3 0 0 3 3 3 0 PQQ-like domain UvrC_HhH_N PF08459.11 OWF55834.1 - 0.099 12.6 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Tissue_fac PF01108.17 OWF55834.1 - 0.39 10.6 12.4 0.41 10.5 0.2 4.5 4 0 0 4 4 4 0 Tissue factor SPRR2 PF14820.6 OWF55835.1 - 0.0014 18.6 61.0 10 6.3 2.3 8.2 1 1 6 7 7 7 3 Small proline-rich 2 PmbA_TldD PF01523.16 OWF55835.1 - 4.2 7.1 8.7 1.5e+04 -4.5 8.7 7.3 1 1 0 1 1 1 0 Putative modulator of DNA gyrase DUF1736 PF08409.11 OWF55836.1 - 7.3e-31 106.0 0.6 2e-30 104.6 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 OWF55836.1 - 3.9e-20 70.3 0.4 0.0023 17.9 0.1 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 OWF55836.1 - 6.1e-20 70.1 2.6 1.8e-05 24.4 0.1 7.6 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OWF55836.1 - 6.3e-19 66.6 0.0 0.0046 17.1 0.1 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 OWF55836.1 - 3.6e-17 61.8 2.7 0.00014 21.4 0.1 6.5 5 1 2 7 7 7 4 TPR repeat TPR_19 PF14559.6 OWF55836.1 - 3.3e-15 56.3 0.9 0.0018 18.7 0.0 5.8 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF55836.1 - 7.7e-15 54.9 0.7 1.5e-06 28.4 0.0 6.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OWF55836.1 - 3.4e-12 45.8 8.9 0.42 11.1 0.1 8.9 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 OWF55836.1 - 7.9e-09 36.0 0.0 0.029 15.0 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OWF55836.1 - 4.5e-08 33.3 0.2 2.2 9.3 0.0 7.2 4 4 4 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 OWF55836.1 - 3.8e-06 26.6 1.2 0.45 10.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF55836.1 - 6e-06 25.9 0.0 0.47 10.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OWF55836.1 - 8.5e-06 26.1 0.1 0.096 13.4 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OWF55836.1 - 0.00019 21.5 0.0 0.81 9.9 0.0 4.3 4 1 0 5 5 5 1 Tetratricopeptide repeat PMT_2 PF13231.6 OWF55836.1 - 0.0021 18.3 10.2 0.0021 18.3 10.2 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIT PF04212.18 OWF55836.1 - 0.16 12.1 0.1 30 4.8 0.0 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 OWF55836.1 - 0.17 11.3 0.9 0.5 9.7 0.1 2.0 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 OWF55836.1 - 0.27 10.9 0.4 10 5.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 OWF55836.1 - 0.44 10.8 6.7 1.9 8.7 0.3 3.5 4 0 0 4 4 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_12 PF13087.6 OWF55838.1 - 7.5e-58 195.4 0.6 9.4e-57 191.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 OWF55838.1 - 6.4e-55 186.7 0.4 8.7e-55 186.3 0.4 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OWF55838.1 - 2.3e-10 41.0 0.0 1.8e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OWF55838.1 - 1.4e-08 34.7 0.0 7e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 OWF55838.1 - 2.8e-07 30.4 0.6 6.7e-06 25.8 0.3 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 OWF55838.1 - 2.4e-05 24.2 0.1 3.8 7.2 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OWF55838.1 - 0.00099 18.4 1.7 0.023 13.9 0.1 3.1 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OWF55838.1 - 0.0036 17.7 0.1 0.015 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 OWF55838.1 - 0.0052 16.7 0.0 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 Helicase NACHT PF05729.12 OWF55838.1 - 0.059 13.3 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Ank_2 PF12796.7 OWF55841.1 - 6.2e-19 68.4 8.0 1.9e-13 50.8 0.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OWF55841.1 - 4.8e-11 42.6 1.6 0.005 17.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OWF55841.1 - 3.4e-09 36.8 1.8 0.00093 19.5 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF55841.1 - 1.8e-08 34.8 0.9 4.2e-05 24.0 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF55841.1 - 4.3e-08 32.8 0.6 0.82 10.4 0.1 4.3 5 0 0 5 5 5 3 Ankyrin repeat Death PF00531.22 OWF55841.1 - 0.064 13.4 0.3 0.99 9.6 0.1 2.8 3 0 0 3 3 3 0 Death domain PI-PLC-X PF00388.19 OWF55842.1 - 0.0023 17.5 0.1 0.0043 16.7 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain APOBEC4 PF18775.1 OWF55842.1 - 0.012 15.8 0.1 0.039 14.1 0.0 1.9 2 0 0 2 2 2 0 APOBEC4 PRA1 PF03208.19 OWF55843.1 - 1.1e-36 125.5 7.7 1.3e-36 125.3 7.7 1.0 1 0 0 1 1 1 1 PRA1 family protein NnrS PF05940.12 OWF55843.1 - 0.0011 18.5 5.3 0.0013 18.2 5.3 1.1 1 0 0 1 1 1 1 NnrS protein YqjK PF13997.6 OWF55843.1 - 0.17 12.2 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 YqjK-like protein DUF2244 PF10003.9 OWF55843.1 - 0.43 10.2 6.6 0.22 11.2 0.4 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) SPC25 PF06703.11 OWF55843.1 - 3.7 7.3 6.0 2.6 7.8 4.1 1.7 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ThiF PF00899.21 OWF55844.1 - 7.2e-64 215.5 0.0 1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OWF55844.1 - 3.5e-24 84.7 1.6 5.6e-24 84.1 1.6 1.3 1 0 0 1 1 1 1 E2 binding domain Pyr_redox PF00070.27 OWF55844.1 - 0.021 15.4 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OWF55844.1 - 0.024 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 OWF55844.1 - 0.067 13.8 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain TrkA_N PF02254.18 OWF55844.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OWF55844.1 - 0.15 12.3 0.1 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_L18A PF01775.17 OWF55845.1 - 8.1e-53 177.7 0.6 1.1e-52 177.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A US30 PF17624.2 OWF55845.1 - 0.019 14.1 0.2 0.024 13.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function DUF2887 PF11103.8 OWF55845.1 - 0.02 14.9 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) RhodobacterPufX PF11511.8 OWF55845.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Xpo1 PF08389.12 OWF55846.1 - 3e-40 137.7 4.3 3.8e-40 137.4 0.5 3.2 3 1 0 3 3 3 1 Exportin 1-like protein FGase PF05013.12 OWF55846.1 - 0.098 12.9 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase PDZ PF00595.24 OWF55847.1 - 1.2e-72 240.3 16.3 1.3e-15 57.5 0.4 6.5 6 0 0 6 6 6 6 PDZ domain PDZ_6 PF17820.1 OWF55847.1 - 3.7e-40 135.6 13.2 7.3e-11 41.8 0.1 6.9 7 0 0 7 7 7 5 PDZ domain PDZ_2 PF13180.6 OWF55847.1 - 5e-25 87.6 1.3 7.9e-06 26.1 0.0 5.8 6 0 0 6 6 6 5 PDZ domain WW PF00397.26 OWF55847.1 - 5.3e-14 52.0 6.5 4.5e-08 33.0 1.3 2.6 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.21 OWF55847.1 - 5.2e-10 39.3 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 OWF55847.1 - 0.00027 20.8 1.7 4.6 7.3 0.0 4.8 5 0 0 5 5 5 2 Tricorn protease PDZ domain YIEGIA PF14045.6 OWF55847.1 - 0.015 14.2 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 YIEGIA protein AKAP7_NLS PF10469.9 OWF55848.1 - 2.6e-39 135.2 0.3 1.4e-38 132.8 0.0 2.1 2 1 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain MJ1316 PF04457.12 OWF55848.1 - 3.6e-26 91.7 1.2 1e-25 90.2 1.2 1.9 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain RWD PF05773.22 OWF55848.1 - 8.7e-10 38.9 0.0 3.7e-09 36.9 0.0 2.1 1 0 0 1 1 1 1 RWD domain 2_5_RNA_ligase2 PF13563.6 OWF55848.1 - 0.00068 19.6 0.0 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily SLX9 PF15341.6 OWF55848.1 - 0.0029 18.0 3.3 0.0029 18.0 3.3 1.9 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 TFIIA PF03153.13 OWF55848.1 - 0.0048 17.0 8.6 0.0065 16.5 8.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LigT_PEase PF02834.16 OWF55848.1 - 0.0049 17.0 0.1 0.41 10.9 0.0 2.8 3 0 0 3 3 3 1 LigT like Phosphoesterase D123 PF07065.14 OWF55848.1 - 0.0073 15.5 7.7 0.13 11.4 1.9 2.5 2 0 0 2 2 2 2 D123 Peptidase_M24_C PF16188.5 OWF55848.1 - 0.02 15.0 0.2 0.73 9.9 0.0 2.6 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 GAGA_bind PF06217.12 OWF55848.1 - 0.11 12.8 4.2 0.19 12.0 4.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2796 PF10986.8 OWF55848.1 - 2.3 8.1 8.8 10 6.1 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) CDC45 PF02724.14 OWF55848.1 - 2.7 6.2 16.5 0.33 9.2 3.8 2.1 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.6 OWF55848.1 - 3.7 7.2 12.5 5 6.8 4.6 2.3 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 OWF55848.1 - 4.5 7.3 13.9 0.35 10.9 1.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal V_ATPase_I PF01496.19 OWF55848.1 - 5.5 4.8 9.3 0.38 8.6 4.1 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PTPRCAP PF15713.5 OWF55848.1 - 6.9 7.0 17.9 5.6 7.2 6.5 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 OWF55848.1 - 8.9 6.5 10.5 10 6.3 5.7 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2457 PF10446.9 OWF55848.1 - 9.6 5.2 23.3 0.4 9.8 12.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CD20 PF04103.15 OWF55849.1 - 5.5e-12 46.0 11.5 1.2e-11 45.0 11.5 1.5 1 0 0 1 1 1 1 CD20-like family PHO4 PF01384.20 OWF55849.1 - 0.67 8.9 2.4 1.1 8.2 2.5 1.3 1 1 0 1 1 1 0 Phosphate transporter family DUF2070 PF09843.9 OWF55849.1 - 0.79 7.9 5.2 1 7.6 5.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) OTU PF02338.19 OWF55850.1 - 1.4e-05 25.6 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-met PF12874.7 OWF55850.1 - 0.024 15.0 0.1 0.062 13.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Kindlin_2_N PF18124.1 OWF55850.1 - 0.12 12.6 0.1 4.8 7.4 0.0 2.5 2 1 0 2 2 2 0 Kindlin-2 N-terminal domain 6PF2K PF01591.18 OWF55851.1 - 1.1e-89 299.6 0.2 2.3e-89 298.5 0.1 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OWF55851.1 - 3.3e-42 144.4 0.0 7.3e-42 143.3 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OWF55851.1 - 4.6e-08 33.3 0.0 8.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OWF55851.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 OWF55851.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sushi PF00084.20 OWF55853.1 - 1.3e-05 25.7 0.7 2.9e-05 24.6 0.7 1.7 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Ebola_NP PF05505.12 OWF55853.1 - 7.5 4.7 13.8 9.1 4.4 13.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein U83 PF17465.2 OWF55854.1 - 0.35 11.0 3.0 0.6 10.3 0.2 2.3 2 0 0 2 2 2 0 Chemokine-like protein, HHV-6 U83 gene product Sushi PF00084.20 OWF55855.1 - 0.0077 16.8 0.9 0.0077 16.8 0.9 2.0 2 1 0 2 2 2 1 Sushi repeat (SCR repeat) DUF2878 PF11086.8 OWF55855.1 - 0.011 16.0 2.3 0.016 15.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) Sushi PF00084.20 OWF55856.1 - 3.5e-06 27.5 0.6 7.1e-06 26.5 0.6 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Ion_trans PF00520.31 OWF55857.1 - 1e-39 136.3 12.3 1.4e-39 135.8 12.3 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 OWF55857.1 - 1.5e-25 89.3 0.2 2.8e-25 88.5 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 OWF55857.1 - 2e-11 43.7 11.0 3.8e-11 42.8 8.9 2.4 2 0 0 2 2 2 1 Ion channel DUF202 PF02656.15 OWF55857.1 - 0.046 14.2 3.1 4.7 7.7 0.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ca_hom_mod PF14798.6 OWF55858.1 - 0.014 14.5 0.1 0.018 14.2 0.1 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator NNMT_PNMT_TEMT PF01234.17 OWF55860.1 - 1.3e-22 80.2 0.0 1.5e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family TMEM43 PF07787.12 OWF55861.1 - 2.1e-79 266.5 0.0 2.7e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 43 Plasmodium_HRP PF05403.11 OWF55863.1 - 0.012 15.5 1.1 0.015 15.1 1.1 1.3 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) 7tm_1 PF00001.21 OWF55864.1 - 3.8e-07 29.7 0.1 4.2e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Nmad5 PF18757.1 OWF55865.1 - 0.12 12.6 0.3 0.23 11.6 0.3 1.5 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 DAAD PF18752.1 OWF55866.1 - 0.44 10.3 3.6 0.61 9.9 3.6 1.3 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Herpes_gE PF02480.16 OWF55867.1 - 0.0002 20.3 0.0 0.00025 19.9 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 OWF55867.1 - 0.00027 21.7 0.0 0.00059 20.7 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OWF55867.1 - 0.00059 19.2 2.8 0.0011 18.4 2.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Protocadherin PF08374.11 OWF55867.1 - 0.00063 19.8 0.0 0.00071 19.6 0.0 1.2 1 0 0 1 1 1 1 Protocadherin Mid2 PF04478.12 OWF55867.1 - 0.0021 17.9 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor RCR PF12273.8 OWF55867.1 - 0.016 15.8 6.4 0.021 15.5 2.3 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF2615 PF11027.8 OWF55867.1 - 0.019 15.1 0.2 1.2 9.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) PTP_tm PF18861.1 OWF55867.1 - 0.021 14.8 0.3 0.04 13.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Chordopox_A13L PF05961.11 OWF55867.1 - 0.032 14.5 0.0 0.64 10.3 0.0 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein TMEM154 PF15102.6 OWF55867.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Cytomega_TRL10 PF06084.11 OWF55867.1 - 0.04 13.9 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Orf78 PF06024.12 OWF55867.1 - 0.044 14.1 0.4 0.25 11.7 0.0 2.4 1 1 2 3 3 3 0 Orf78 (ac78) DUF5385 PF17359.2 OWF55867.1 - 0.05 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Syndecan PF01034.20 OWF55867.1 - 0.068 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.6 OWF55867.1 - 0.1 12.9 1.8 0.11 12.8 0.7 1.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Pkinase PF00069.25 OWF55868.1 - 2.3e-64 217.3 1.1 3.8e-64 216.6 1.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55868.1 - 2.8e-53 180.9 0.2 4.1e-53 180.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF55868.1 - 4.1e-07 29.1 0.2 1.4e-06 27.3 0.0 1.8 1 1 1 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OWF55868.1 - 0.00068 19.3 0.3 0.0017 18.0 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 OWF55868.1 - 0.00078 18.9 0.1 0.0025 17.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OWF55868.1 - 0.023 14.0 0.0 0.087 12.1 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 OWF55869.1 - 7.3e-62 209.1 2.0 1.4e-61 208.2 0.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55869.1 - 1.1e-46 159.2 0.7 1.5e-46 158.8 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF55869.1 - 2.2e-08 33.3 3.0 8.8e-07 28.0 0.0 3.0 2 2 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 OWF55869.1 - 3.2e-05 23.4 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OWF55869.1 - 0.0021 17.7 1.8 0.0033 17.1 0.2 2.0 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 OWF55869.1 - 0.0041 16.5 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF55869.1 - 0.068 13.1 0.0 7.3 6.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OWF55869.1 - 0.45 10.1 4.3 0.95 9.0 1.2 2.6 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OWF55870.1 - 1.4e-63 214.8 0.0 2.7e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55870.1 - 6.4e-49 166.6 0.0 1.2e-48 165.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OWF55870.1 - 0.00036 19.4 2.6 0.00043 19.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OWF55870.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MHC_I_3 PF16497.5 OWF55870.1 - 0.023 14.2 0.1 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 MHC-I family domain APH PF01636.23 OWF55870.1 - 0.11 12.3 0.0 2.6 7.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 OWF55871.1 - 2.3e-41 141.9 24.0 2.8e-37 128.5 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OWF55871.1 - 4.7e-09 35.6 26.3 0.0011 17.9 2.3 4.1 3 1 0 4 4 4 4 Sugar (and other) transporter MFS_2 PF13347.6 OWF55871.1 - 9.7e-05 21.1 2.0 9.7e-05 21.1 2.0 3.4 3 1 0 4 4 4 3 MFS/sugar transport protein GvpK PF05121.12 OWF55872.1 - 7.1e-05 22.8 0.2 1.3 9.1 0.0 3.1 3 0 0 3 3 3 2 Gas vesicle protein K DUF1979 PF09322.10 OWF55872.1 - 0.021 14.7 0.9 9.3 6.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1979) SAP PF02037.27 OWF55872.1 - 0.076 12.8 0.7 0.12 12.1 0.7 1.4 1 0 0 1 1 1 0 SAP domain DUF4251 PF14059.6 OWF55872.1 - 0.11 12.4 0.3 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) DUF4502 PF14950.6 OWF55872.1 - 1.3 8.3 3.4 11 5.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) SNF2_N PF00176.23 OWF55874.1 - 2.9e-50 171.0 0.0 5.1e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OWF55874.1 - 6.2e-14 52.3 0.0 1.5e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF55874.1 - 7e-06 26.1 0.9 3.9e-05 23.7 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OWF55874.1 - 0.18 11.0 0.0 0.18 11.0 0.0 2.8 2 1 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 OWF55875.1 - 1.3e-13 51.2 11.4 1.1e-05 26.1 0.1 7.2 7 1 1 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55875.1 - 8.1e-13 48.5 0.3 0.0087 16.3 0.0 6.2 2 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF55875.1 - 0.00027 20.9 0.3 0.18 11.7 0.0 3.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OWF55875.1 - 0.0073 15.4 5.6 1.2 8.1 0.0 5.1 4 1 2 6 6 6 1 Coatomer WD associated region Clathrin PF00637.20 OWF55875.1 - 0.008 16.1 12.8 0.05 13.5 0.3 4.9 3 1 2 5 5 5 1 Region in Clathrin and VPS Ge1_WD40 PF16529.5 OWF55875.1 - 0.011 14.7 0.2 0.24 10.3 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S51 PF03575.17 OWF55875.1 - 0.028 14.1 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S51 zinc_ribbon_9 PF14369.6 OWF55875.1 - 2.1 8.7 11.6 10 6.5 0.9 2.7 2 0 0 2 2 2 0 zinc-ribbon TPR_2 PF07719.17 OWF55875.1 - 2.2 8.6 17.4 21 5.6 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 OWF55875.1 - 2.3 8.2 9.7 3.7 7.5 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_22 PF03901.17 OWF55876.1 - 1.2e-43 150.0 24.9 1.5e-43 149.6 24.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ADP_ribosyl_GH PF03747.14 OWF55877.1 - 9.4e-40 137.2 0.0 1.4e-39 136.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_8 PF13855.6 OWF55877.1 - 1.3e-18 66.4 26.5 1.8e-09 37.2 2.5 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OWF55877.1 - 9.6e-11 41.8 16.1 2.5e-05 24.6 3.7 4.4 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OWF55877.1 - 0.0053 16.3 0.9 0.018 14.6 0.7 1.9 1 1 0 1 1 1 1 Leucine-rich repeat DUF3775 PF12616.8 OWF55877.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) LRR_1 PF00560.33 OWF55877.1 - 0.82 10.5 16.8 28 5.8 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat EGF_CA PF07645.15 OWF55878.1 - 2.3e-100 328.6 297.2 3.5e-09 36.7 11.3 20.3 18 1 1 19 19 19 16 Calcium-binding EGF domain cEGF PF12662.7 OWF55878.1 - 1.2e-71 236.1 191.1 2.3e-07 30.6 3.3 22.3 21 1 0 21 21 21 18 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF55878.1 - 4.1e-37 126.2 295.8 4.5e-08 33.2 11.0 21.5 16 3 4 20 20 20 16 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 OWF55878.1 - 4.8e-09 36.3 323.6 5.7e-05 23.2 12.7 22.2 21 3 0 21 21 21 13 EGF domain TSP_1 PF00090.19 OWF55878.1 - 9.2e-06 25.8 10.4 9.2e-06 25.8 10.4 4.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain NIDO PF06119.14 OWF55878.1 - 0.00091 20.1 0.1 0.0038 18.1 0.1 2.2 1 0 0 1 1 1 1 Nidogen-like EGF PF00008.27 OWF55878.1 - 0.0045 17.3 270.9 0.0088 16.3 6.5 22.5 22 3 1 23 23 23 12 EGF-like domain EGF_MSP1_1 PF12946.7 OWF55878.1 - 0.0072 16.4 4.9 0.0072 16.4 4.9 17.9 18 1 1 19 19 19 6 MSP1 EGF domain 1 RIFIN PF02009.16 OWF55878.1 - 3 7.7 5.0 6.5 6.6 5.0 1.6 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 OWF55879.1 - 0.00068 18.6 0.0 0.00095 18.1 0.0 1.2 1 0 0 1 1 1 1 Amnionless Insulin_TMD PF17870.1 OWF55879.1 - 0.26 11.4 1.8 0.6 10.2 1.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Baculo_11_kDa PF06143.11 OWF55879.1 - 0.7 9.5 2.2 1.6 8.4 2.2 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3011 PF11218.8 OWF55880.1 - 5.8e-13 49.3 1.2 5.8e-13 49.3 1.2 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3011) DUF3707 PF12499.8 OWF55880.1 - 0.0046 17.5 3.4 0.0064 17.1 3.4 1.2 1 0 0 1 1 1 1 Pherophorin Ly49 PF08391.10 OWF55880.1 - 3.2 8.1 5.1 53 4.2 2.8 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region SLAC1 PF03595.17 OWF55882.1 - 0.0006 19.2 0.4 0.0006 19.2 0.4 2.0 2 0 0 2 2 2 2 Voltage-dependent anion channel Podoplanin PF05808.11 OWF55883.1 - 0.00082 19.5 0.1 0.0012 19.0 0.1 1.2 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 OWF55883.1 - 0.0011 18.8 0.6 0.0017 18.2 0.6 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Shisa PF13908.6 OWF55883.1 - 0.0017 18.6 0.2 0.0024 18.2 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RHINO PF15319.6 OWF55883.1 - 0.026 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Hanta_G2 PF01561.16 OWF55883.1 - 0.065 11.9 0.1 0.096 11.3 0.1 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 DAP10 PF07213.11 OWF55883.1 - 0.071 13.1 1.1 0.14 12.1 0.9 1.6 1 1 0 1 1 1 0 DAP10 membrane protein MtrG PF04210.13 OWF55883.1 - 0.074 12.9 0.4 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3827 PF12877.7 OWF55883.1 - 0.18 10.1 0.9 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Shisa PF13908.6 OWF55884.1 - 9.1e-07 29.3 7.1 9.1e-07 29.3 7.1 2.3 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OWF55884.1 - 0.0068 17.3 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Myc_target_1 PF15179.6 OWF55884.1 - 0.024 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 Comm PF15957.5 OWF55884.1 - 0.026 14.9 0.1 0.061 13.7 0.1 1.6 1 0 0 1 1 1 0 Commissureless Tir_receptor_C PF07489.11 OWF55884.1 - 0.032 14.2 0.8 0.047 13.6 0.8 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus EstA_Ig_like PF18435.1 OWF55884.1 - 0.035 14.3 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain Adeno_E3_CR2 PF02439.15 OWF55884.1 - 0.31 10.9 12.9 0.55 10.0 12.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1218 PF06749.12 OWF55884.1 - 0.37 11.3 5.6 0.27 11.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) SUR7 PF06687.12 OWF55884.1 - 6.7 6.3 8.9 10 5.7 8.9 1.4 1 1 0 1 1 1 0 SUR7/PalI family TMIE PF16038.5 OWF55884.1 - 7.1 6.5 7.1 13 5.7 7.1 1.4 1 0 0 1 1 1 0 TMIE protein MTS PF05175.14 OWF55885.1 - 2.9e-08 33.4 0.0 6.6e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OWF55885.1 - 1.1e-07 32.4 0.0 7.5e-07 29.8 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF55885.1 - 1.4e-06 28.2 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OWF55885.1 - 1.7e-06 27.8 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmC_N PF17827.1 OWF55885.1 - 1.8e-06 28.4 0.0 3.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_16 PF10294.9 OWF55885.1 - 1.1e-05 25.2 0.0 3.1e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 OWF55885.1 - 7e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OWF55885.1 - 0.00017 22.2 0.0 0.00045 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OWF55885.1 - 0.00017 21.2 0.0 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 OWF55885.1 - 0.0072 16.9 0.0 0.026 15.1 0.0 2.0 2 1 1 3 3 1 1 Methyltransferase domain DUF938 PF06080.12 OWF55885.1 - 0.017 14.9 0.0 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) RrnaAD PF00398.20 OWF55885.1 - 0.04 13.0 0.0 0.086 11.9 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 OWF55885.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 OWF55885.1 - 0.06 13.3 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 OWF55885.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_24 PF13578.6 OWF55885.1 - 0.18 12.9 0.0 0.48 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.26 OWF55886.1 - 1.6e-58 197.4 0.1 2.1e-58 197.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OWF55886.1 - 1.1e-13 50.5 0.0 2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SOCS_box PF07525.16 OWF55887.1 - 0.00021 21.5 0.2 0.00021 21.5 0.2 1.9 2 0 0 2 2 2 1 SOCS box Ank_3 PF13606.6 OWF55887.1 - 0.024 15.1 0.0 0.14 12.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Herpes_BLLF1 PF05109.13 OWF55888.1 - 0.56 8.1 22.6 0.83 7.6 22.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Ank_4 PF13637.6 OWF55889.1 - 3.3e-09 37.1 3.8 0.011 16.4 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF55889.1 - 1.3e-07 32.1 7.4 0.0021 18.6 0.2 3.9 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF55889.1 - 6.5e-07 29.5 7.5 2.1 8.7 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF55889.1 - 8.9e-05 22.8 6.0 0.19 12.2 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_3 PF13606.6 OWF55889.1 - 0.0029 18.0 3.4 12 6.9 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Na_trans_assoc PF06512.13 OWF55889.1 - 1.6 9.0 4.2 0.78 10.0 1.8 1.7 2 0 0 2 2 2 0 Sodium ion transport-associated Pkinase PF00069.25 OWF55890.1 - 8.5e-46 156.4 0.0 1.4e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55890.1 - 5.7e-29 101.2 0.0 1.4e-28 99.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OWF55890.1 - 0.005 16.8 0.0 2.2 8.2 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OWF55890.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TBK1_ULD PF18396.1 OWF55890.1 - 0.028 14.4 0.2 0.086 12.8 0.2 1.8 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Qua1 PF16274.5 OWF55890.1 - 0.041 13.7 0.3 0.49 10.3 0.0 2.5 2 0 0 2 2 2 0 Qua1 domain TSNAXIP1_N PF15739.5 OWF55890.1 - 0.096 13.1 0.5 0.25 11.7 0.5 1.8 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus ABC1 PF03109.16 OWF55890.1 - 0.12 12.5 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 ABC1 family Alpha_L_fucos PF01120.17 OWF55891.1 - 4.4e-68 230.3 1.1 5.1e-68 230.1 1.1 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF55891.1 - 0.00067 20.2 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 OWF55891.1 - 0.009 16.1 0.1 0.074 13.2 0.0 2.2 1 1 1 2 2 2 1 Lactococcus bacteriophage putative transcription regulator Pkinase PF00069.25 OWF55892.1 - 1.3e-44 152.5 0.0 2.2e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF55892.1 - 2.5e-25 89.2 0.0 4.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_CCD1 PF18394.1 OWF55892.1 - 1.9e-08 34.2 9.7 1.2e-07 31.6 8.0 2.5 2 1 0 2 2 2 1 TANK-binding kinase 1 coiled-coil domain 1 TBK1_ULD PF18396.1 OWF55892.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Syntaxin-6_N PF09177.11 OWF55892.1 - 0.028 15.0 0.0 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Med9 PF07544.13 OWF55892.1 - 0.13 12.4 0.3 2.1 8.5 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 EzrA PF06160.12 OWF55892.1 - 0.16 10.1 0.5 1.1 7.4 0.1 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Aldedh PF00171.22 OWF55893.1 - 5.2e-167 556.0 0.4 6.6e-167 555.7 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fasciclin PF02469.22 OWF55893.1 - 1.8e-47 160.8 0.1 9.3e-23 80.9 0.0 2.5 2 0 0 2 2 2 2 Fasciclin domain Nrf1_DNA-bind PF10491.9 OWF55894.1 - 3.7e-17 62.7 0.0 8.4e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF2841 PF11001.8 OWF55894.1 - 0.0095 16.0 1.4 0.014 15.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) zf-C2H2_jaz PF12171.8 OWF55894.1 - 0.017 15.4 0.3 0.04 14.2 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OWF55894.1 - 0.024 15.1 0.1 0.078 13.5 0.1 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-MYST PF17772.1 OWF55894.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain zf-C2H2 PF00096.26 OWF55895.1 - 1.2e-20 72.7 32.5 8.4e-06 26.0 2.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF55895.1 - 2.9e-16 59.1 28.9 2e-07 31.1 0.2 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF55895.1 - 3.6e-15 55.3 27.1 0.00022 21.8 0.2 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF55895.1 - 6.1e-09 35.7 2.4 6.7e-06 26.0 0.0 4.5 5 0 0 5 5 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF55895.1 - 4.8e-05 23.0 1.5 4.8e-05 23.0 1.5 4.4 5 0 0 5 5 5 2 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 OWF55895.1 - 0.018 14.9 12.4 0.3 11.0 4.2 3.5 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_9 PF16293.5 OWF55895.1 - 0.054 13.3 6.5 0.11 12.4 1.4 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 OWF55895.1 - 0.12 12.1 12.0 0.05 13.4 3.4 3.3 4 0 0 4 4 3 0 zinc-finger C2H2-type MyTH4 PF00784.17 OWF55895.1 - 0.28 11.7 2.0 0.26 11.8 0.3 1.8 2 0 0 2 2 1 0 MyTH4 domain Zn-ribbon_8 PF09723.10 OWF55895.1 - 0.86 9.8 12.9 0.11 12.6 4.4 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 OWF55895.1 - 1.6 9.0 11.2 1.2 9.5 5.5 3.1 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 OWF55895.1 - 2.1 8.0 14.6 0.47 10.1 0.1 3.7 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 OWF55895.1 - 2.2 8.7 9.2 0.31 11.4 1.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OWF55895.1 - 2.8 8.3 14.6 3.9 7.9 0.1 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2225 PF09986.9 OWF55895.1 - 3.5 7.3 8.7 11 5.6 5.7 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 OWF55895.1 - 3.9 8.3 10.1 6.1 7.7 1.3 2.4 1 1 1 2 2 2 0 zinc-ribbon family zf-met PF12874.7 OWF55895.1 - 6.2 7.4 13.2 1.8 9.0 2.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OWF55895.1 - 7.8 6.9 16.6 14 6.1 5.0 3.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF829 PF05705.14 OWF55896.1 - 0.0094 15.9 0.0 37 4.1 0.0 4.7 2 2 2 6 6 6 1 Eukaryotic protein of unknown function (DUF829) DUF364 PF04016.12 OWF55896.1 - 0.16 11.5 0.7 1.7e+02 1.7 0.0 4.5 5 0 0 5 5 5 0 Putative heavy-metal chelation T4-Gluco-transf PF09198.10 OWF55896.1 - 0.23 11.1 47.2 6.8 6.4 0.1 13.7 13 5 5 18 18 18 0 Bacteriophage T4 beta-glucosyltransferase Wza_C PF18412.1 OWF55896.1 - 4.1 7.2 9.2 1.8e+02 2.0 0.2 5.3 5 0 0 5 5 5 0 Outer-membrane lipoprotein Wza C-terminal domain zf-B_box PF00643.24 OWF55898.1 - 8.2e-06 25.9 8.3 1.3e-05 25.2 8.3 1.3 1 0 0 1 1 1 1 B-box zinc finger Peptidase_C2 PF00648.21 OWF55899.1 - 5.1e-107 357.3 2.4 6.7e-107 356.9 2.4 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF55899.1 - 2.9e-22 79.5 0.0 5.6e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 OWF55899.1 - 5.4e-09 36.3 0.6 1.2e-07 31.9 0.1 2.9 3 0 0 3 3 3 1 C2 domain Glyco_transf_25 PF01755.17 OWF55900.1 - 0.0014 18.5 0.1 0.0041 17.0 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) MTHFR PF02219.17 OWF55900.1 - 0.21 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Glyco_transf_25 PF01755.17 OWF55901.1 - 0.0076 16.1 0.2 0.014 15.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glycos_transf_2 PF00535.26 OWF55901.1 - 0.03 14.1 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DZF PF07528.14 OWF55902.1 - 5.7e-96 320.9 0.0 7.6e-96 320.5 0.0 1.1 1 0 0 1 1 1 1 DZF domain SMODS PF18144.1 OWF55902.1 - 0.031 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Neur_chan_LBD PF02931.23 OWF55903.1 - 2.6e-37 128.4 0.2 3.8e-37 127.8 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF55903.1 - 2.5e-13 50.7 4.2 2.5e-13 50.7 4.2 1.9 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF55904.1 - 3.8e-40 137.6 0.3 6.8e-40 136.8 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF55904.1 - 6.1e-14 52.7 0.4 1.1e-13 51.8 0.4 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Peptidase_U4 PF03419.13 OWF55904.1 - 4.7 6.4 10.0 0.93 8.7 2.9 2.4 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Na_Ca_ex PF01699.24 OWF55905.1 - 7.1e-47 159.2 37.2 1e-24 87.2 13.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 OWF55905.1 - 1.5e-44 150.3 2.4 8e-22 77.3 0.2 2.5 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex_C PF16494.5 OWF55905.1 - 0.0012 19.3 0.1 0.0031 18.0 0.0 1.6 2 0 0 2 2 2 1 C-terminal extension of sodium/calcium exchanger domain Ribosomal_L7Ae PF01248.26 OWF55906.1 - 6e-21 74.0 0.0 9.1e-21 73.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OWF55906.1 - 0.026 14.6 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 NMT_C PF02799.15 OWF55906.1 - 0.079 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Rad51 PF08423.11 OWF55907.1 - 1.2e-108 362.2 0.0 1.5e-108 361.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OWF55907.1 - 8.1e-12 45.1 0.0 1.2e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OWF55907.1 - 8.5e-08 32.0 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 OWF55907.1 - 5.5e-07 30.1 0.4 4.9e-06 27.0 0.3 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NRD1_2 PF01995.16 OWF55907.1 - 4.1e-05 23.0 0.1 7.1e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 ATPase PF06745.13 OWF55907.1 - 0.00021 20.7 0.4 0.00073 19.0 0.4 2.0 1 1 0 1 1 1 1 KaiC NeuB PF03102.14 OWF55907.1 - 0.012 15.1 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 NeuB family DnaB_C PF03796.15 OWF55907.1 - 0.016 14.5 0.5 0.33 10.3 0.0 2.5 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 OWF55907.1 - 0.021 14.6 0.1 0.063 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Tsc35 PF15079.6 OWF55907.1 - 0.062 12.9 0.3 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Testis-specific protein 35 AMP-binding PF00501.28 OWF55908.1 - 6e-105 351.3 0.0 8.2e-105 350.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF55908.1 - 0.014 16.3 0.0 0.04 14.9 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Spc24 PF08286.11 OWF55909.1 - 3.7e-11 43.2 3.6 3.7e-11 43.2 3.6 1.7 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 OWF55909.1 - 0.0053 16.8 13.0 0.0089 16.1 13.0 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OWF55909.1 - 0.011 14.6 8.2 0.014 14.3 8.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec34 PF04136.15 OWF55909.1 - 0.027 14.4 4.0 0.064 13.1 1.6 2.1 2 0 0 2 2 2 0 Sec34-like family FPP PF05911.11 OWF55909.1 - 0.043 12.0 8.0 0.052 11.7 8.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 OWF55909.1 - 0.069 13.2 13.6 0.18 11.9 13.6 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain GAS PF13851.6 OWF55909.1 - 0.077 12.3 11.7 0.99 8.7 7.9 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding U3_assoc_6 PF08640.11 OWF55909.1 - 0.11 12.6 2.4 5.5 7.1 0.0 2.4 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Death PF00531.22 OWF55909.1 - 0.12 12.6 3.3 0.2 11.8 0.5 2.2 2 0 0 2 2 2 0 Death domain Tup_N PF08581.10 OWF55909.1 - 0.13 12.6 8.4 1.4 9.3 4.8 2.5 2 1 0 2 2 2 0 Tup N-terminal DUF4407 PF14362.6 OWF55909.1 - 0.22 10.8 10.2 0.29 10.5 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) She9_MDM33 PF05546.11 OWF55909.1 - 0.3 10.9 10.0 0.077 12.8 4.1 2.0 1 1 1 2 2 2 0 She9 / Mdm33 family Mod_r PF07200.13 OWF55909.1 - 0.3 11.2 13.2 0.72 9.9 11.7 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Sec8_exocyst PF04048.14 OWF55909.1 - 0.39 10.6 7.1 0.059 13.3 2.6 1.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain PSP1 PF04468.12 OWF55909.1 - 0.44 10.9 3.1 0.45 10.8 1.5 1.9 2 1 0 2 2 1 0 PSP1 C-terminal conserved region ATP-synt_D PF01813.17 OWF55909.1 - 0.44 10.4 6.7 0.31 10.8 3.1 2.0 1 1 1 2 2 2 0 ATP synthase subunit D COG2 PF06148.11 OWF55909.1 - 0.47 10.6 8.1 2.7 8.1 7.9 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ZYG-11_interact PF05884.12 OWF55909.1 - 0.51 9.7 1.6 0.65 9.4 1.2 1.3 1 1 0 1 1 1 0 Interactor of ZYG-11 Complex1_LYR_2 PF13233.6 OWF55909.1 - 1.5 9.6 5.6 59 4.5 5.6 3.0 1 1 0 1 1 1 0 Complex1_LYR-like APG6_N PF17675.1 OWF55909.1 - 2 8.9 14.3 4.7 7.7 14.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 OWF55909.1 - 3.5 6.8 8.8 6.4 5.9 8.8 1.5 1 1 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 OWF55909.1 - 4.4 7.1 10.1 1.5 8.6 7.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 OWF55909.1 - 5.9 7.2 10.9 12 6.2 5.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 OWF55909.1 - 9.5 5.2 12.7 35 3.4 12.7 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliD_N PF02465.18 OWF55909.1 - 9.9 6.9 10.5 2.7 8.7 5.4 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Aa_trans PF01490.18 OWF55910.1 - 5.7e-57 193.3 26.5 1.7e-38 132.4 10.2 3.1 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein Polysacc_synt_C PF14667.6 OWF55910.1 - 0.0095 16.0 7.0 0.0095 16.0 7.0 3.9 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain zf-H2C2_2 PF13465.6 OWF55911.1 - 1.1e-21 76.2 41.6 1.6e-06 28.2 1.5 6.9 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 OWF55911.1 - 2e-19 68.8 41.8 0.0015 18.9 1.3 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF55911.1 - 3.1e-18 64.9 37.9 0.0023 18.6 1.3 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 OWF55911.1 - 1.2e-12 47.8 27.1 0.0033 17.8 0.3 6.6 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF55911.1 - 3.3e-08 33.6 29.7 0.0051 17.1 0.7 6.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF55911.1 - 1.2e-05 25.1 36.3 0.16 12.0 1.1 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OWF55911.1 - 0.0086 15.8 26.6 0.024 14.4 0.3 4.9 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-Di19 PF05605.12 OWF55911.1 - 0.0086 16.4 19.1 0.44 10.9 2.4 3.8 1 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 OWF55911.1 - 0.02 15.2 23.1 0.054 13.8 12.1 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 OWF55911.1 - 0.032 14.9 17.5 0.89 10.2 1.3 4.6 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 OWF55911.1 - 0.068 13.1 16.8 0.49 10.3 0.5 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf_C2H2_13 PF18508.1 OWF55911.1 - 0.087 12.4 2.1 13 5.5 0.1 2.8 2 0 0 2 2 2 0 Zinc finger domain zf-MYST PF17772.1 OWF55911.1 - 0.24 11.1 8.6 0.34 10.6 0.1 3.9 4 1 1 5 5 5 0 MYST family zinc finger domain Zn-ribbon_8 PF09723.10 OWF55911.1 - 0.45 10.7 14.0 6.9 6.9 0.0 4.5 4 1 2 6 6 4 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 OWF55911.1 - 0.54 11.0 18.1 5.2 7.9 0.3 4.1 1 1 2 3 3 3 0 zinc-ribbon family zf-DBF PF07535.12 OWF55911.1 - 1.8 8.8 6.0 0.55 10.4 0.2 2.9 3 0 0 3 3 3 0 DBF zinc finger Spt46 PF17734.1 OWF55911.1 - 4.3 7.1 13.5 2.5 7.9 0.8 3.5 2 1 1 3 3 3 0 Spermatogenesis-associated protein 46 C1_4 PF07975.12 OWF55911.1 - 7.4 6.9 15.3 6.5 7.1 0.4 3.8 3 1 0 3 3 3 0 TFIIH C1-like domain DUF2256 PF10013.9 OWF55911.1 - 9.9 6.4 13.7 31 4.8 0.2 5.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Integrase_H2C2 PF17921.1 OWF55912.1 - 8.7e-27 93.0 2.2 1.9e-11 43.9 0.0 3.6 3 0 0 3 3 3 3 Integrase zinc binding domain zf-H2C2 PF09337.10 OWF55912.1 - 5e-06 26.6 4.0 1.1e-05 25.5 0.3 2.7 2 0 0 2 2 2 1 H2C2 zinc finger rve PF00665.26 OWF55912.1 - 0.067 13.4 0.1 0.7 10.1 0.0 2.7 3 0 0 3 3 3 0 Integrase core domain DUF3128 PF11326.8 OWF55912.1 - 0.42 11.0 4.9 1.8 9.0 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Actin PF00022.19 OWF55913.1 - 3.1e-70 236.9 0.5 7.1e-35 120.4 0.3 3.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 OWF55913.1 - 2.1e-05 23.5 0.0 8e-05 21.6 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 OWF55913.1 - 0.041 13.4 0.1 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family EphA2_TM PF14575.6 OWF55916.1 - 0.00056 20.7 0.0 0.0038 18.1 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF55916.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family DUF4381 PF14316.6 OWF55916.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) AP_endonuc_2 PF01261.24 OWF55917.1 - 4.8e-30 104.6 0.0 8.1e-30 103.8 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Robl_LC7 PF03259.17 OWF55918.1 - 4.4e-14 52.0 0.1 6e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain SGT1 PF07093.11 OWF55919.1 - 1.6e-212 707.1 0.0 1.9e-212 706.8 0.0 1.0 1 0 0 1 1 1 1 SGT1 protein RRN3 PF05327.11 OWF55919.1 - 0.89 8.0 4.2 1.6 7.2 4.2 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 APH PF01636.23 OWF55920.1 - 1.7e-08 34.7 0.0 5e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OWF55920.1 - 0.00011 21.9 0.2 0.00017 21.2 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OWF55920.1 - 0.011 14.6 0.1 0.016 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Lactamase_B_2 PF12706.7 OWF55921.1 - 3.7e-15 56.0 0.3 1.1e-14 54.5 0.3 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OWF55921.1 - 1.1e-07 32.0 0.1 3.2e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 OWF55921.1 - 1.9e-07 30.7 1.1 2.6e-05 23.8 0.0 3.9 4 0 0 4 4 4 1 tRNase Z endonuclease Lactamase_B_6 PF16661.5 OWF55921.1 - 0.0023 17.4 0.0 0.0065 15.9 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain IQ PF00612.27 OWF55921.1 - 0.0026 17.4 4.2 0.0092 15.7 4.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Not3 PF04065.15 OWF55922.1 - 1.6e-89 299.3 24.6 1.6e-89 299.3 24.6 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OWF55922.1 - 1.1e-42 145.2 10.0 6e-42 142.8 10.0 2.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CK2S PF15011.6 OWF55922.1 - 0.022 14.6 2.7 0.56 10.1 0.1 3.0 2 1 0 2 2 2 0 Casein Kinase 2 substrate DUF402 PF04167.13 OWF55922.1 - 0.04 14.1 1.2 0.12 12.6 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF402) Baculo_PEP_C PF04513.12 OWF55922.1 - 0.34 11.0 3.2 4.3 7.4 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus P4Ha_N PF08336.11 OWF55922.1 - 0.87 9.6 8.3 0.7 9.9 1.1 2.9 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.15 OWF55922.1 - 1.7 8.5 8.6 1.5 8.6 1.6 3.0 2 0 0 2 2 2 0 Septum formation initiator Syntaxin_2 PF14523.6 OWF55922.1 - 1.8 9.0 14.3 1.4 9.4 0.4 3.7 3 0 0 3 3 3 0 Syntaxin-like protein DUF3847 PF12958.7 OWF55922.1 - 2 8.6 13.5 4 7.6 4.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF4407 PF14362.6 OWF55922.1 - 2.4 7.5 11.5 0.58 9.4 8.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YlqD PF11068.8 OWF55922.1 - 2.7 8.4 12.9 0.53 10.7 2.9 2.8 2 0 0 2 2 2 0 YlqD protein FlaC_arch PF05377.11 OWF55922.1 - 2.8 8.4 5.6 1.8 9.0 0.4 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MYO10_CC PF16735.5 OWF55922.1 - 4.5 7.5 9.5 5.5 7.2 0.5 2.8 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain Pyrophosphatase PF00719.19 OWF55923.1 - 3.3e-57 192.8 1.0 4.4e-57 192.3 1.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase HMG_box PF00505.19 OWF55924.1 - 1.7e-21 76.4 0.8 3.5e-21 75.4 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OWF55924.1 - 1.6e-07 31.8 1.8 1.6e-07 31.8 1.8 1.8 2 0 0 2 2 2 1 HMG-box domain CTNNB1_binding PF08347.11 OWF55924.1 - 0.0026 18.0 4.2 0.0033 17.6 0.1 2.9 3 1 0 3 3 3 1 N-terminal CTNNB1 binding DUF4062 PF13271.6 OWF55925.1 - 1.5e-12 47.7 0.0 6.3e-12 45.7 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) NACHT PF05729.12 OWF55925.1 - 1.4e-09 38.1 0.0 5e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OWF55925.1 - 9.9e-08 32.3 0.0 5.7e-06 26.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain WD40 PF00400.32 OWF55925.1 - 2.4e-07 31.3 3.1 0.0024 18.7 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF55925.1 - 1.2e-06 28.7 3.3 0.0042 17.4 0.0 4.4 4 3 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 OWF55925.1 - 3.7e-06 27.4 0.0 2.7e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Torsin PF06309.11 OWF55925.1 - 0.0022 18.1 0.4 0.0072 16.4 0.0 2.0 2 0 0 2 2 2 1 Torsin Nup160 PF11715.8 OWF55925.1 - 0.0076 14.9 9.4 0.02 13.6 0.5 3.1 3 1 0 4 4 4 2 Nucleoporin Nup120/160 AAA PF00004.29 OWF55925.1 - 0.0077 16.7 0.0 0.027 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OWF55925.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OWF55925.1 - 0.083 13.2 0.1 2.1 8.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain PQQ_2 PF13360.6 OWF55925.1 - 0.19 11.3 0.4 2.4 7.7 0.0 2.7 2 1 0 3 3 3 0 PQQ-like domain Mito_carr PF00153.27 OWF55926.1 - 5.8e-57 189.6 2.0 2.6e-19 68.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.8 OWF55926.1 - 0.24 11.8 3.2 9.1 6.7 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3147) Mito_carr PF00153.27 OWF55927.1 - 1.2e-56 188.6 4.0 4.3e-20 71.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OWF55927.1 - 0.084 12.0 3.7 1.5 7.9 3.7 2.8 1 1 0 1 1 1 0 Gammaproteobacterial serine protease PKD_channel PF08016.12 OWF55928.1 - 3.2e-75 253.4 24.0 3.2e-75 253.4 24.0 2.2 3 0 0 3 3 2 1 Polycystin cation channel REJ PF02010.15 OWF55928.1 - 1.1e-62 212.4 23.2 1.1e-62 212.4 23.2 5.3 4 1 0 5 5 4 1 REJ domain PKD PF00801.20 OWF55928.1 - 9.5e-44 147.1 174.7 9.6e-09 35.0 2.5 19.2 19 1 0 19 19 18 13 PKD domain PLAT PF01477.23 OWF55928.1 - 1.6e-18 67.3 1.5 1.3e-17 64.4 0.7 3.1 2 0 0 2 2 2 1 PLAT/LH2 domain Lectin_C PF00059.21 OWF55928.1 - 1.6e-16 60.9 16.8 3.9e-13 50.1 1.3 4.4 4 0 0 4 4 3 2 Lectin C-type domain LRR_8 PF13855.6 OWF55928.1 - 1.3e-15 56.9 12.3 9.7e-09 34.9 1.0 3.3 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OWF55928.1 - 8.5e-11 41.9 13.0 0.00016 21.9 0.9 4.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) GPS PF01825.21 OWF55928.1 - 1.8e-08 34.7 1.1 1.8e-08 34.7 1.1 3.5 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif Gly-zipper_Omp PF13488.6 OWF55928.1 - 0.00016 21.6 13.0 0.014 15.3 4.4 2.8 1 1 1 2 2 2 2 Glycine zipper Rick_17kDa_Anti PF05433.15 OWF55928.1 - 0.012 15.4 11.9 0.16 11.8 6.5 2.9 1 1 1 2 2 2 0 Glycine zipper 2TM domain LRR_1 PF00560.33 OWF55928.1 - 0.1 13.2 1.2 1.9e+02 3.3 0.0 5.0 3 1 0 3 3 3 0 Leucine Rich Repeat Gly-zipper_YMGG PF13441.6 OWF55928.1 - 0.11 12.3 8.7 0.049 13.4 1.1 3.1 2 1 1 3 3 3 0 YMGG-like Gly-zipper DUF5427 PF10310.9 OWF55928.1 - 0.24 10.3 10.1 0.44 9.5 10.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Y_Y_Y PF07495.13 OWF55928.1 - 0.62 10.1 20.9 0.31 11.0 0.6 6.3 7 0 0 7 7 7 0 Y_Y_Y domain DUF5008 PF16400.5 OWF55928.1 - 0.97 9.6 8.6 0.22 11.7 0.4 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF5008) PKD_3 PF16820.5 OWF55928.1 - 2 8.2 23.6 0.72 9.6 0.3 6.2 5 0 0 5 5 5 0 PKD-like domain Gly-zipper_OmpA PF13436.6 OWF55928.1 - 4.5 7.2 6.2 12 5.8 1.6 2.7 1 1 1 2 2 2 0 Glycine-zipper domain Hid1 PF12722.7 OWF55929.1 - 2.4e-46 158.3 0.0 2.7e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OWF55929.1 - 3.1e-34 118.4 0.0 3.1e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 OWF55930.1 - 4.7e-100 336.0 0.0 6e-100 335.6 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OWF55930.1 - 1.7e-78 264.6 0.1 2e-78 264.4 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ank_2 PF12796.7 OWF55931.1 - 7.5e-74 244.4 26.5 7.7e-15 55.3 0.1 8.9 2 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF55931.1 - 1.2e-58 194.7 12.0 3.2e-07 30.8 0.0 11.5 5 3 7 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF55931.1 - 1.4e-54 181.4 9.8 3.5e-07 30.4 0.0 12.1 6 3 6 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 OWF55931.1 - 2.5e-51 170.0 25.4 0.0025 18.2 0.0 15.4 15 0 0 15 15 15 12 Ankyrin repeat Ank_3 PF13606.6 OWF55931.1 - 4.1e-42 137.3 19.9 0.0075 16.7 0.0 15.8 17 0 0 17 17 17 10 Ankyrin repeat SOCS_box PF07525.16 OWF55931.1 - 0.015 15.6 0.1 0.015 15.6 0.1 1.8 2 0 0 2 2 2 0 SOCS box RPN7 PF10602.9 OWF55931.1 - 0.083 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 SLT PF01464.20 OWF55932.1 - 1.2e-11 44.3 33.0 37 4.0 0.1 17.4 1 1 21 22 22 22 20 Transglycosylase SLT domain Pyr_redox_3 PF13738.6 OWF55933.1 - 3.3e-37 128.4 0.0 4.4e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF55933.1 - 8.6e-15 54.7 0.0 1.7e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OWF55933.1 - 5.1e-09 35.1 0.0 6.9e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OWF55933.1 - 1.9e-08 33.8 0.0 4.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OWF55933.1 - 4.5e-05 22.3 0.0 0.026 13.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OWF55933.1 - 0.0013 19.2 0.0 7.5 7.2 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OWF55933.1 - 0.0018 18.5 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OWF55933.1 - 0.0026 17.8 0.0 0.0056 16.7 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 OWF55933.1 - 0.003 17.2 0.0 0.28 10.7 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase YaiA PF16362.5 OWF55933.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 YaiA protein GH3 PF03321.13 OWF55933.1 - 0.052 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Peptidase_M24 PF00557.24 OWF55934.1 - 1.2e-46 159.1 0.1 1.4e-46 158.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OWF55934.1 - 9e-20 70.7 8.2 9e-20 70.7 8.2 1.9 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OWF55934.1 - 0.0087 16.1 2.6 0.022 14.8 2.6 1.7 1 0 0 1 1 1 1 MYND finger V-SNARE_C PF12352.8 OWF55935.1 - 8.2e-05 22.8 0.8 56 4.1 0.1 5.9 5 2 2 7 7 7 1 Snare region anchored in the vesicle membrane C-terminus MACPF PF01823.19 OWF55935.1 - 2.4 8.2 6.1 15 5.6 0.1 4.6 2 2 2 5 5 5 0 MAC/Perforin domain cNMP_binding PF00027.29 OWF55936.1 - 2.4e-46 155.7 0.0 5.9e-22 77.5 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OWF55936.1 - 1.3e-09 37.5 0.0 3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ASCH PF04266.14 OWF55937.1 - 1.9e-17 63.7 0.0 1.4e-16 61.0 0.0 2.3 2 0 0 2 2 2 1 ASCH domain zf-C2HC5 PF06221.13 OWF55937.1 - 1.6e-09 37.6 13.3 3.2e-09 36.6 13.3 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SRF-TF PF00319.18 OWF55938.1 - 1.3e-23 82.2 0.3 1.9e-23 81.6 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GHD PF17834.1 OWF55938.1 - 0.062 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase C2-C2_1 PF11618.8 OWF55939.1 - 0.17 12.0 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 Granulin PF00396.18 OWF55940.1 - 2.2 8.7 11.2 4.9 7.6 3.1 2.7 2 0 0 2 2 2 0 Granulin JHY PF15261.6 OWF55942.1 - 3.3e-25 89.3 15.5 3.3e-25 89.3 15.5 5.2 5 1 1 6 6 6 2 Jhy protein AIG1 PF04548.16 OWF55943.1 - 5.7e-51 172.9 0.9 7.3e-51 172.5 0.9 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OWF55943.1 - 1.8e-07 31.2 0.4 6.6e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OWF55943.1 - 0.0027 18.2 0.0 0.0081 16.7 0.0 1.9 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OWF55943.1 - 0.0048 16.8 0.8 0.014 15.3 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OWF55943.1 - 0.023 15.0 0.1 0.056 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OWF55943.1 - 0.063 12.6 1.1 0.31 10.3 0.2 2.2 2 1 0 2 2 2 0 Septin SRPRB PF09439.10 OWF55943.1 - 0.07 12.6 0.1 0.15 11.5 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OWF55943.1 - 0.21 11.6 2.1 3.1 7.8 0.0 2.8 1 1 2 3 3 3 0 Dynamin family AIG1 PF04548.16 OWF55944.1 - 5.9e-23 81.3 0.8 6.8e-23 81.1 0.8 1.0 1 0 0 1 1 1 1 AIG1 family DUF1330 PF07045.11 OWF55944.1 - 0.016 15.5 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Lectin_C PF00059.21 OWF55945.1 - 5.2e-06 27.1 0.1 1.5e-05 25.7 0.1 1.9 1 0 0 1 1 1 1 Lectin C-type domain YscW PF09619.10 OWF55945.1 - 0.0081 16.5 0.4 4.8 7.6 0.1 2.4 1 1 1 2 2 2 2 Type III secretion system lipoprotein chaperone (YscW) Methyltransf_11 PF08241.12 OWF55946.1 - 3.9e-20 72.3 0.0 8.7e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF55946.1 - 9.9e-18 64.6 0.0 1.7e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF55946.1 - 3.4e-13 49.6 0.0 4.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF55946.1 - 4.1e-11 43.5 0.0 6.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF55946.1 - 2e-09 37.1 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF55946.1 - 2.5e-08 34.0 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OWF55946.1 - 0.0031 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 OWF55946.1 - 0.006 15.9 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OWF55946.1 - 0.0075 16.3 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OWF55946.1 - 0.0088 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 OWF55946.1 - 0.0094 15.4 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 OWF55946.1 - 0.014 13.9 0.0 0.039 12.5 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 OWF55946.1 - 0.041 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TPMT PF05724.11 OWF55946.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 OWF55947.1 - 7.2e-13 49.0 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF55947.1 - 7.2e-11 42.6 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF55947.1 - 9e-07 28.5 0.0 1.7e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OWF55947.1 - 7.5e-06 25.8 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF55947.1 - 1.7e-05 25.5 0.0 2.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF55947.1 - 0.069 13.0 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3419 PF11899.8 OWF55947.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_11 PF08241.12 OWF55948.1 - 6.6e-20 71.6 0.0 1.1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF55948.1 - 3.9e-18 65.9 0.0 6.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF55948.1 - 4.3e-13 49.3 0.0 6.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF55948.1 - 1.3e-10 41.9 0.0 2.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OWF55948.1 - 1.7e-08 34.1 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OWF55948.1 - 4.1e-07 30.0 0.0 5.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OWF55948.1 - 7.5e-06 25.4 0.0 9.3e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 OWF55948.1 - 0.0007 19.3 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 OWF55948.1 - 0.0022 17.9 0.0 0.0049 16.7 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 OWF55948.1 - 0.0071 15.8 0.3 0.15 11.5 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_15 PF09445.10 OWF55948.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.16 OWF55948.1 - 0.059 11.9 0.0 0.1 11.1 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 OWF55948.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DsrH PF04077.12 OWF55949.1 - 0.07 13.3 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 DsrH like protein RRM_1 PF00076.22 OWF55950.1 - 4.4e-18 64.9 0.0 8.6e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRCT PF00533.26 OWF55951.1 - 0.06 13.7 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.22 OWF55952.1 - 6.5e-14 51.5 0.0 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF55952.1 - 0.00024 20.7 0.0 0.00053 19.6 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OWF55952.1 - 0.0029 17.4 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF2877 PF11392.8 OWF55953.1 - 2.2e-05 25.1 21.9 3.6 8.3 0.2 6.6 2 2 5 7 7 7 6 Protein of unknown function (DUF2877) An_peroxidase PF03098.15 OWF55956.1 - 7.6e-176 585.8 0.1 9.9e-176 585.4 0.1 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Galactosyl_T PF01762.21 OWF55957.1 - 5.5e-47 160.1 0.1 7.3e-47 159.7 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF55957.1 - 0.0028 17.2 1.6 0.018 14.5 1.6 2.0 1 1 0 1 1 1 1 Fringe-like 7tm_1 PF00001.21 OWF55958.1 - 0.0013 18.1 5.8 0.0013 18.1 5.8 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 OWF55958.1 - 0.13 12.0 6.6 0.17 11.7 6.6 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DEAD PF00270.29 OWF55959.1 - 4.9e-43 146.9 0.0 7.1e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF55959.1 - 3e-28 98.4 1.1 1.2e-27 96.5 0.5 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OWF55959.1 - 9.8e-06 25.7 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OWF55959.1 - 0.0097 15.1 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Atg14 PF10186.9 OWF55960.1 - 0.00012 21.3 1.6 0.00012 21.3 1.6 2.3 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 OWF55960.1 - 0.00051 20.1 13.7 0.081 13.0 0.1 3.9 3 1 1 4 4 4 2 bZIP transcription factor Rootletin PF15035.6 OWF55960.1 - 0.00065 19.8 6.6 0.00065 19.8 6.6 1.9 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 OWF55960.1 - 0.0016 18.5 19.7 0.26 11.3 2.2 3.6 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 OWF55960.1 - 0.002 18.2 11.2 0.057 13.5 1.1 4.1 3 1 0 4 4 4 1 Basic region leucine zipper SKA2 PF16740.5 OWF55960.1 - 0.003 17.3 3.9 0.01 15.6 0.6 2.6 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 2 GIT_CC PF16559.5 OWF55960.1 - 0.0047 16.8 4.9 1.9 8.4 0.0 3.6 3 1 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 OWF55960.1 - 0.0054 17.3 10.1 0.045 14.4 3.2 2.9 1 1 1 2 2 2 1 Initiation control protein YabA THP2 PF09432.10 OWF55960.1 - 0.0093 16.0 9.0 0.17 11.9 2.9 2.4 2 1 0 2 2 2 2 Tho complex subunit THP2 TSC22 PF01166.18 OWF55960.1 - 0.011 16.0 14.7 0.37 11.1 0.1 4.2 4 1 1 5 5 4 0 TSC-22/dip/bun family WD40_alt PF14077.6 OWF55960.1 - 0.011 15.5 1.1 0.011 15.5 1.1 2.5 3 0 0 3 3 2 0 Alternative WD40 repeat motif Cep57_MT_bd PF06657.13 OWF55960.1 - 0.011 16.1 1.4 0.011 16.1 1.4 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Shugoshin_N PF07558.11 OWF55960.1 - 0.015 15.1 6.7 0.94 9.4 0.9 3.8 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region FAM76 PF16046.5 OWF55960.1 - 0.02 14.2 13.1 0.57 9.5 4.8 2.2 1 1 1 2 2 2 0 FAM76 protein SlyX PF04102.12 OWF55960.1 - 0.025 15.2 4.9 13 6.5 0.4 3.6 3 1 1 4 4 4 0 SlyX T2SSM_b PF10741.9 OWF55960.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b KLRAQ PF10205.9 OWF55960.1 - 0.029 14.6 1.0 0.029 14.6 1.0 2.5 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Exonuc_VII_L PF02601.15 OWF55960.1 - 0.046 13.3 5.7 0.092 12.3 5.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dam1 PF08653.10 OWF55960.1 - 0.069 13.0 0.1 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 DivIC PF04977.15 OWF55960.1 - 0.09 12.6 13.7 0.42 10.4 0.2 3.7 3 1 1 4 4 4 0 Septum formation initiator COG5 PF10392.9 OWF55960.1 - 0.11 12.6 8.2 0.43 10.7 1.5 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Spc29 PF17082.5 OWF55960.1 - 0.22 11.4 4.8 0.47 10.2 0.3 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 Csm1_N PF18504.1 OWF55960.1 - 0.22 11.9 17.2 3 8.3 3.8 4.1 3 1 2 5 5 5 0 Csm1 N-terminal domain FAM184 PF15665.5 OWF55960.1 - 0.29 10.9 15.0 0.28 10.9 10.7 2.5 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B APG17 PF04108.12 OWF55960.1 - 0.36 9.9 10.7 0.13 11.3 7.3 1.8 1 1 1 2 2 2 0 Autophagy protein Apg17 Cnn_1N PF07989.11 OWF55960.1 - 0.58 10.3 17.4 0.72 10.1 0.3 3.9 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 OWF55960.1 - 0.64 10.4 7.1 6.9 7.1 0.3 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 OWF55960.1 - 0.87 8.9 7.7 0.49 9.7 4.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 OWF55960.1 - 4.6 7.8 16.8 40 4.8 5.3 3.7 1 1 1 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 OWF55960.1 - 6.4 7.1 10.3 1.4 9.2 0.3 3.3 3 1 0 3 3 3 0 Homeobox associated leucine zipper Med9 PF07544.13 OWF55960.1 - 6.7 6.9 10.4 0.87 9.7 0.5 3.2 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HalX PF08663.10 OWF55960.1 - 7.4 7.0 9.6 0.27 11.6 2.0 2.5 3 1 0 3 3 2 0 HalX domain Zona_pellucida PF00100.23 OWF55961.1 - 3.2e-10 40.2 5.7 4.9e-10 39.6 5.3 1.5 1 1 0 1 1 1 1 Zona pellucida-like domain DUF1540 PF07561.11 OWF55961.1 - 1 9.7 6.8 4.1 7.8 4.8 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) Zona_pellucida PF00100.23 OWF55962.1 - 0.0003 20.7 0.3 0.00042 20.2 0.3 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain SOG2 PF10428.9 OWF55962.1 - 0.042 13.1 22.5 0.064 12.5 22.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 OWF55962.1 - 0.19 10.4 16.5 0.26 9.9 16.5 1.2 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 OWF55962.1 - 1.5 7.4 10.3 1.9 7.1 10.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zona_pellucida PF00100.23 OWF55964.1 - 7e-13 49.0 7.7 1.1e-12 48.4 7.7 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain PEX11 PF05648.14 OWF55965.1 - 2.4e-33 115.5 0.6 2.7e-33 115.3 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CotH PF08757.11 OWF55965.1 - 0.11 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 CotH kinase protein Gag_p19 PF02228.16 OWF55967.1 - 0.0017 18.8 14.3 0.12 12.9 1.6 4.1 2 2 1 4 4 4 3 Major core protein p19 TMEM126 PF07114.11 OWF55967.1 - 1.8 7.9 21.2 6.3 6.1 0.1 5.8 2 1 4 6 6 6 0 Transmembrane protein 126 Spaetzle PF16077.5 OWF55969.1 - 9.5e-05 22.9 2.9 0.00017 22.0 2.9 1.5 1 0 0 1 1 1 1 Spaetzle Sclerostin PF05463.11 OWF55969.1 - 0.0049 16.6 1.7 0.0085 15.8 1.7 1.3 1 0 0 1 1 1 1 Sclerostin (SOST) Reticulon PF02453.17 OWF55970.1 - 0.21 11.5 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Reticulon Curlin_rpt PF07012.12 OWF55972.1 - 0.0006 19.8 5.3 0.11 12.5 0.1 12.2 12 2 1 14 14 14 7 Curlin associated repeat Pou PF00157.17 OWF55973.1 - 9e-38 128.1 0.1 1.7e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 OWF55973.1 - 2.3e-19 69.0 1.0 5.8e-19 67.7 1.0 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 OWF55973.1 - 0.029 14.7 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.11 OWF55973.1 - 0.035 14.0 0.1 0.089 12.7 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain TACC_C PF05010.14 OWF55974.1 - 0.028 14.2 4.1 0.026 14.3 3.0 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 OWF55974.1 - 0.041 13.2 0.3 0.051 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 OWF55974.1 - 0.053 12.9 0.2 0.068 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PDDEXK_6 PF04720.12 OWF55974.1 - 0.13 12.2 1.8 0.18 11.7 1.8 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Nup88 PF10168.9 OWF55974.1 - 0.46 8.2 3.3 0.57 7.9 3.3 1.1 1 0 0 1 1 1 0 Nuclear pore component Myb_DNA-binding PF00249.31 OWF55975.1 - 9.4e-06 25.7 1.2 4.2e-05 23.6 0.8 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF55975.1 - 0.00081 19.6 0.1 0.0025 18.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 OWF55975.1 - 0.0088 16.4 0.4 0.66 10.4 0.0 2.9 2 1 0 2 2 2 1 SWIRM domain DUF3363 PF11843.8 OWF55975.1 - 0.1 11.5 0.4 0.2 10.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3363) DUF3612 PF12268.8 OWF55975.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) DUF3060 PF11259.8 OWF55976.1 - 1.5e-07 31.0 2.2 0.03 14.0 0.1 3.7 1 1 4 5 5 5 5 Protein of unknown function (DUF3060) DUF1236 PF06823.12 OWF55976.1 - 0.003 17.4 1.5 98 2.9 0.0 5.6 4 2 1 5 5 5 0 Protein of unknown function (DUF1236) TLP1_add_C PF18313.1 OWF55976.1 - 0.63 10.0 7.2 33 4.5 0.1 4.0 2 1 2 5 5 5 0 Thiolase-like protein type 1 additional C-terminal domain 7tm_1 PF00001.21 OWF55977.1 - 2.1e-50 171.5 20.7 3e-50 171.0 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF55977.1 - 3.6e-14 52.8 21.7 5.1e-14 52.3 21.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 OWF55977.1 - 4.4e-05 23.0 14.9 4.4e-05 23.0 14.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 OWF55977.1 - 0.0018 17.9 23.9 0.0021 17.7 22.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx ETRAMP PF09716.10 OWF55977.1 - 4.5 7.4 6.1 2.2 8.4 2.0 2.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PDZ PF00595.24 OWF55978.1 - 5.5e-79 260.6 4.6 3.6e-19 68.9 0.6 5.7 5 0 0 5 5 5 5 PDZ domain Y_phosphatase PF00102.27 OWF55978.1 - 1.8e-74 250.3 2.3 3.6e-74 249.3 2.3 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ_6 PF17820.1 OWF55978.1 - 1.5e-41 140.0 1.5 6.6e-10 38.7 0.1 5.6 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 OWF55978.1 - 1.8e-29 101.8 1.6 1.5e-05 25.2 0.0 6.1 6 0 0 6 6 6 5 PDZ domain FERM_M PF00373.18 OWF55978.1 - 9.8e-25 87.3 0.1 3.8e-24 85.4 0.1 2.1 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 OWF55978.1 - 1.4e-14 54.2 0.6 2.9e-14 53.2 0.6 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 OWF55978.1 - 3.3e-14 52.6 0.0 7.2e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain Tricorn_PDZ PF14685.6 OWF55978.1 - 0.0022 17.9 0.4 18 5.4 0.0 5.0 5 0 0 5 5 5 0 Tricorn protease PDZ domain KIND PF16474.5 OWF55978.1 - 0.0071 16.3 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain Y_phosphatase3 PF13350.6 OWF55978.1 - 0.03 14.3 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 OWF55978.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ADIP PF11559.8 OWF55979.1 - 0.016 15.3 5.2 0.016 15.3 5.2 3.8 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Vps39_2 PF10367.9 OWF55979.1 - 0.023 15.1 2.2 0.023 15.1 2.2 3.0 2 2 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Lebercilin PF15619.6 OWF55979.1 - 0.032 13.9 45.1 0.017 14.8 20.7 3.9 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease FUSC PF04632.12 OWF55979.1 - 0.72 8.3 4.6 1.1 7.7 4.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family T3SSipB PF16535.5 OWF55979.1 - 0.84 10.1 13.5 0.22 12.0 7.3 2.6 2 0 0 2 2 2 0 Type III cell invasion protein SipB TipAS PF07739.13 OWF55979.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.5 3 1 1 4 4 4 0 TipAS antibiotic-recognition domain Jnk-SapK_ap_N PF09744.9 OWF55979.1 - 1.9 8.7 52.9 0.13 12.5 10.1 4.1 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 Taxilin PF09728.9 OWF55979.1 - 2.3 7.3 47.6 0.019 14.1 7.1 4.3 3 1 1 4 4 4 0 Myosin-like coiled-coil protein DUF99 PF01949.16 OWF55979.1 - 4.2 6.8 4.7 2.4 7.5 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF99 BRI3BP PF14965.6 OWF55979.1 - 5.4 6.5 5.0 14 5.2 0.2 2.9 3 0 0 3 3 3 0 Negative regulator of p53/TP53 HSBP1 PF06825.12 OWF55979.1 - 5.7 6.9 10.7 0.12 12.3 0.9 3.3 4 0 0 4 4 4 0 Heat shock factor binding protein 1 YvrJ PF12841.7 OWF55979.1 - 9.1 5.9 8.2 2.2 7.9 0.3 3.2 3 1 0 3 3 3 0 YvrJ protein family Voltage_CLC PF00654.20 OWF55980.1 - 1.3e-94 317.4 15.0 1.3e-94 317.4 15.0 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OWF55980.1 - 1.9e-10 41.0 0.1 0.0013 19.2 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF1564 PF07600.11 OWF55980.1 - 0.13 12.0 0.5 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) DUF2651 PF10852.8 OWF55980.1 - 0.15 12.7 3.8 0.73 10.5 3.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) Sin_N PF04801.13 OWF55981.1 - 3.7e-144 481.1 0.1 9.4e-141 469.9 0.0 2.3 2 1 0 2 2 2 2 Sin-like protein conserved region PBP1_TM PF14812.6 OWF55981.1 - 6.2 7.3 7.6 9.6 6.7 4.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PP28 PF10252.9 OWF55982.1 - 8.5e-25 87.0 22.3 8.5e-25 87.0 22.3 2.2 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 G10 PF01125.17 OWF55983.1 - 5.5e-66 220.8 4.6 6.1e-66 220.7 4.6 1.0 1 0 0 1 1 1 1 G10 protein Exo_endo_phos PF03372.23 OWF55984.1 - 4.9e-09 36.1 0.0 7.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EGF_CA PF07645.15 OWF55985.1 - 4.1e-80 263.7 165.4 1.8e-09 37.6 8.0 13.6 11 2 2 13 13 13 10 Calcium-binding EGF domain cEGF PF12662.7 OWF55985.1 - 2.5e-55 184.0 99.3 3.7e-10 39.5 1.9 14.0 11 2 1 12 12 12 11 Complement Clr-like EGF-like FXa_inhibition PF14670.6 OWF55985.1 - 4.3e-19 68.5 164.8 6.2e-07 29.6 8.8 13.0 13 0 0 13 13 13 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 OWF55985.1 - 6.1e-10 39.1 132.9 6.2e-05 23.1 2.9 14.1 11 3 2 13 13 13 10 EGF domain EGF PF00008.27 OWF55985.1 - 1.4e-08 34.9 143.7 0.00022 21.5 5.2 13.8 13 0 0 13 13 13 6 EGF-like domain hEGF PF12661.7 OWF55985.1 - 0.015 15.9 22.4 0.021 15.4 5.2 15.4 13 2 0 13 13 13 0 Human growth factor-like EGF Actino_peptide PF14408.6 OWF55985.1 - 0.17 12.0 0.5 5.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes PAX PF00292.18 OWF55986.1 - 8.6e-66 219.5 0.2 1.3e-65 219.0 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 OWF55986.1 - 5.9e-06 26.8 0.0 0.0041 17.7 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain MHC2-interact PF09307.10 OWF55986.1 - 0.11 12.5 0.3 0.29 11.1 0.3 1.7 2 0 0 2 2 2 0 CLIP, MHC2 interacting HTH_23 PF13384.6 OWF55986.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain QSregVF PF13652.6 OWF55987.1 - 1.8e-05 24.7 6.0 7.1 6.7 0.0 5.4 1 1 5 6 6 6 2 Putative quorum-sensing-regulated virulence factor DUF4179 PF13786.6 OWF55987.1 - 6e-05 23.4 1.1 1.8 9.1 1.1 4.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4179) HVSL PF09749.9 OWF55987.1 - 0.00065 19.2 0.5 6.9 6.1 0.0 3.7 1 1 3 5 5 5 3 Uncharacterised conserved protein ELK PF03789.13 OWF55987.1 - 0.0012 18.8 6.2 29 4.9 0.0 7.5 9 0 0 9 9 9 0 ELK domain DUF3048 PF11258.8 OWF55987.1 - 0.0021 18.2 6.6 0.22 11.6 1.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3048) N-terminal domain DUF4070 PF13282.6 OWF55987.1 - 0.0024 18.0 1.6 34 4.6 0.0 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4070) POTRA_2 PF08479.11 OWF55987.1 - 0.0045 16.8 18.6 7.6 6.4 0.2 7.2 1 1 4 6 6 6 1 POTRA domain, ShlB-type ToxB_N PF18224.1 OWF55987.1 - 0.013 15.4 11.1 3 7.9 0.2 5.1 2 2 4 6 6 6 0 ToxB N-terminal domain HMW1C_N PF18071.1 OWF55987.1 - 0.014 15.2 0.0 3.6 7.4 0.0 2.6 1 1 0 2 2 2 0 HMW1C N-terminal DUF4113 PF13438.6 OWF55987.1 - 0.027 14.6 9.1 17 5.6 0.1 7.5 5 2 3 8 8 8 0 Domain of unknown function (DUF4113) Phage_hub_GP28 PF11110.8 OWF55987.1 - 0.034 14.1 8.1 19 5.2 0.1 5.2 1 1 3 4 4 4 0 Baseplate hub distal subunit Marek_A PF02124.15 OWF55987.1 - 0.5 10.2 13.8 1.2 9.0 1.8 3.1 1 1 2 3 3 3 0 Marek's disease glycoprotein A ANAPC5 PF12862.7 OWF55987.1 - 2.6 8.2 15.9 43 4.3 0.3 4.7 1 1 5 6 6 6 0 Anaphase-promoting complex subunit 5 SWIM PF04434.17 OWF55989.1 - 2.1e-05 24.1 0.7 3.5e-05 23.4 0.7 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF1024 PF06260.12 OWF55989.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) PP2C PF00481.21 OWF55990.1 - 1.9e-54 185.0 0.0 3.2e-54 184.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OWF55990.1 - 0.029 14.0 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein phosphatase 2C Pentapeptide_4 PF13599.6 OWF55991.1 - 0.29 11.3 13.7 11 6.2 0.9 4.2 1 1 3 4 4 4 0 Pentapeptide repeats (9 copies) HC2 PF07382.11 OWF55991.1 - 2.6 8.1 8.0 13 5.8 0.7 2.4 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 dsrm PF00035.26 OWF55992.1 - 9.7e-16 58.2 1.7 2.2e-09 37.9 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif RRM_1 PF00076.22 OWF55994.1 - 5.1e-52 173.6 0.2 3.6e-17 61.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OWF55994.1 - 2.2e-12 46.6 0.6 2.2e-07 30.5 0.1 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OWF55994.1 - 0.0056 16.9 0.0 9.5 6.4 0.0 3.7 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L18A PF01775.17 OWF55994.1 - 0.033 14.3 0.1 22 5.2 0.1 2.9 3 0 0 3 3 3 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Nup35_RRM PF05172.13 OWF55994.1 - 0.057 13.4 0.1 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OWF55994.1 - 0.082 13.0 0.0 11 6.1 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif fn3 PF00041.21 OWF55995.1 - 3.1e-05 24.2 26.5 0.79 10.1 0.0 11.2 15 0 0 15 15 15 3 Fibronectin type III domain Y_Y_Y PF07495.13 OWF55995.1 - 0.013 15.4 0.0 2.1 8.4 0.0 3.2 2 0 0 2 2 2 0 Y_Y_Y domain PPC PF04151.15 OWF55995.1 - 0.35 12.0 7.0 0.31 12.2 0.2 4.7 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain Pyridoxal_deC PF00282.19 OWF55996.1 - 2.9e-156 519.9 0.0 3.5e-156 519.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OWF55996.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase F-box-like PF12937.7 OWF55997.1 - 5.6e-13 48.6 0.9 1.2e-12 47.5 0.9 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OWF55997.1 - 1.4e-11 43.5 23.3 0.0059 16.6 0.0 9.9 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.7 OWF55997.1 - 6.5e-09 35.9 17.5 0.093 13.2 0.2 7.6 3 2 2 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 OWF55997.1 - 0.00026 20.8 0.4 0.00026 20.8 0.4 2.9 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 OWF55997.1 - 0.00068 19.8 22.2 1.1 10.1 0.1 8.4 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 OWF55997.1 - 0.0018 18.0 9.6 0.33 10.7 0.0 5.8 5 3 1 6 6 6 1 Leucine rich repeat Fibrillarin PF01269.17 OWF55997.1 - 0.16 11.1 0.0 3.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Fibrillarin Thioredoxin PF00085.20 OWF55998.1 - 6.6e-07 29.3 0.2 1.1e-06 28.6 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 OWF55998.1 - 0.053 13.3 0.6 0.076 12.8 0.6 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Oxysterol_BP PF01237.18 OWF55999.1 - 8.7e-92 307.8 1.6 2.1e-89 300.0 1.6 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 OWF55999.1 - 5.9e-07 29.9 0.1 1.9e-06 28.4 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF55999.1 - 0.028 14.8 1.7 0.066 13.6 0.2 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain zf-C4 PF00105.18 OWF56000.1 - 8.5e-25 87.0 9.6 8.5e-25 87.0 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF56000.1 - 2.5e-12 46.8 2.7 7.6e-12 45.2 2.7 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Vps26 PF03643.15 OWF56001.1 - 1.6e-133 443.9 7.2 1.9e-133 443.7 7.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 OWF56001.1 - 3.7e-05 24.2 2.3 0.0017 18.8 0.2 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OWF56001.1 - 0.00047 20.2 4.8 0.026 14.6 0.1 3.4 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain LIM PF00412.22 OWF56002.1 - 1e-39 134.5 45.6 1.5e-13 50.7 12.6 3.1 3 0 0 3 3 3 3 LIM domain zf_UBZ PF18439.1 OWF56002.1 - 0.0096 15.5 32.6 0.67 9.6 0.7 6.7 7 0 0 7 7 7 5 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 OWF56002.1 - 0.3 11.2 24.0 0.4 10.8 0.4 6.4 6 0 0 6 6 6 0 Acetyl-coA carboxylase zinc finger domain DUF4428 PF14471.6 OWF56002.1 - 2.5 8.1 22.9 0.25 11.3 0.9 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4428) DUF2616 PF11077.8 OWF56002.1 - 4.6 6.9 17.5 2 8.1 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) Nsp1_C PF05064.13 OWF56003.1 - 2e-33 114.6 11.9 2e-33 114.6 11.9 2.1 1 1 0 1 1 1 1 Nsp1-like C-terminal region Tetraspanin PF00335.20 OWF56003.1 - 1.8e-29 103.1 5.9 3.5e-29 102.2 5.9 1.5 1 0 0 1 1 1 1 Tetraspanin family DUF4834 PF16118.5 OWF56003.1 - 0.13 13.3 5.7 0.15 13.1 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) VirB3 PF05101.13 OWF56003.1 - 2.4 8.4 5.6 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF3487 PF11990.8 OWF56003.1 - 3.8 7.4 5.3 2.9 7.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF1430 PF07242.11 OWF56003.1 - 5.8 7.2 11.8 0.29 11.4 6.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF4282 PF14110.6 OWF56003.1 - 6.5 7.6 12.3 2.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Guanylate_cyc PF00211.20 OWF56004.1 - 4e-58 196.0 0.1 7.3e-58 195.2 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OWF56004.1 - 1.9e-53 181.2 1.7 6.1e-53 179.5 1.7 1.8 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 OWF56004.1 - 8.1e-53 178.7 0.5 1.3e-52 178.1 0.5 1.3 1 0 0 1 1 1 1 Haem-NO-binding Zip PF02535.22 OWF56005.1 - 1.4e-69 234.9 1.3 2.2e-69 234.2 1.3 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter ZIP4_domain PF18292.1 OWF56005.1 - 0.025 14.5 1.3 0.025 14.5 1.3 1.6 2 0 0 2 2 2 0 Zinc transporter ZIP4 domain Leptin PF02024.15 OWF56005.1 - 0.083 12.7 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Leptin C1q PF00386.21 OWF56006.1 - 4.8e-19 68.8 0.1 5.5e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 C1q domain C1q PF00386.21 OWF56007.1 - 2.2e-06 27.9 0.0 2.2e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 C1q domain Cleaved_Adhesin PF07675.11 OWF56007.1 - 0.0027 17.7 0.4 0.003 17.5 0.4 1.0 1 0 0 1 1 1 1 Cleaved Adhesin Domain FIT1_2 PF17357.2 OWF56007.1 - 0.11 12.6 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 MitMem_reg PF13012.6 OWF56008.1 - 0.042 14.3 0.0 0.052 14.0 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function SurA_N_2 PF13623.6 OWF56008.1 - 0.096 12.6 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 SurA N-terminal domain Tom6 PF17112.5 OWF56010.1 - 1.7 8.2 7.2 15 5.2 0.5 3.2 1 1 3 4 4 4 0 Mitochondrial import receptor subunit Tom6, fungal DUF1656 PF07869.12 OWF56012.1 - 0.029 14.4 2.7 9.9 6.3 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1656) MSP1b PF03429.13 OWF56012.1 - 0.33 9.0 8.3 2.6 6.0 0.1 4.0 2 2 3 6 6 6 0 Major surface protein 1B DUF5638 PF18688.1 OWF56014.1 - 4.7e-06 26.9 23.9 0.3 11.4 0.1 6.3 1 1 3 5 5 5 4 Family of unknown function (DUF5638) DNA_ligase_OB PF03120.16 OWF56014.1 - 1.1e-05 25.3 0.3 26 4.8 0.0 7.7 2 2 8 11 11 11 0 NAD-dependent DNA ligase OB-fold domain DASH_Ask1 PF08655.10 OWF56014.1 - 1.2e-05 25.0 23.8 4.4 7.3 0.1 10.6 1 1 11 13 13 13 1 DASH complex subunit Ask1 DUF3148 PF11347.8 OWF56014.1 - 0.00031 20.4 6.7 32 4.4 0.0 8.7 5 3 6 11 11 11 0 Protein of unknown function (DUF3148) G-gamma PF00631.22 OWF56014.1 - 0.0012 18.9 1.4 15 5.6 0.0 6.0 1 1 4 7 7 7 1 GGL domain DUF2524 PF10732.9 OWF56014.1 - 0.0046 17.2 12.1 21 5.5 0.1 7.3 1 1 7 8 8 8 0 Protein of unknown function (DUF2524) Cuticle_3 PF11018.8 OWF56014.1 - 0.014 15.7 44.2 4.6 7.4 14.9 4.3 1 1 2 3 3 3 0 Pupal cuticle protein C1 ArAE_1_C PF11728.8 OWF56014.1 - 0.017 15.1 13.0 1.2 9.2 0.2 4.7 3 1 1 5 5 5 0 Putative aromatic acid exporter C-terminal domain HycI PF01750.18 OWF56014.1 - 1.8 8.4 12.6 17 5.2 0.1 5.2 1 1 3 6 6 6 0 Hydrogenase maturation protease Med28 PF11594.8 OWF56014.1 - 2.5 8.2 11.2 9.4 6.3 1.0 4.2 1 1 5 6 6 6 0 Mediator complex subunit 28 DUF1752 PF08550.10 OWF56014.1 - 5.5 6.9 12.2 3.6e+02 1.1 0.0 8.3 12 0 0 12 12 12 0 Fungal protein of unknown function (DUF1752) 7tm_1 PF00001.21 OWF56015.1 - 2.6e-16 59.8 5.3 3.4e-16 59.3 5.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF56015.1 - 0.00019 20.9 3.6 0.00026 20.5 3.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx AP3D1 PF06375.11 OWF56016.1 - 2.6 8.2 10.5 5 7.4 10.5 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Dimer_Tnp_Tn5 PF02281.16 OWF56017.1 - 0.015 15.0 0.0 20 4.9 0.0 3.0 1 1 3 4 4 4 0 Transposase Tn5 dimerisation domain PAG PF15347.6 OWF56017.1 - 0.088 11.8 2.3 1.9 7.4 0.1 2.3 1 1 1 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched Ribosomal_L36 PF00444.18 OWF56017.1 - 0.3 11.3 28.0 3.5 7.9 0.8 7.6 5 1 1 6 6 6 0 Ribosomal protein L36 ChapFlgA_N PF17656.1 OWF56017.1 - 1.9 8.7 6.8 3.7 7.8 0.1 3.6 3 1 0 3 3 3 0 FlgA N-terminal domain Cornifin PF02389.15 OWF56018.1 - 0.0037 17.5 38.2 0.026 14.7 20.5 2.3 1 1 1 2 2 2 2 Cornifin (SPRR) family DUF3715 PF12509.8 OWF56019.1 - 0.011 15.7 6.7 0.61 10.1 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3715) Plasmodium_HRP PF05403.11 OWF56019.1 - 0.028 14.2 3.2 0.032 14.0 3.2 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Cytochrom_C552 PF02335.15 OWF56019.1 - 5.3 5.9 9.5 6.4 5.6 9.5 1.1 1 0 0 1 1 1 0 Cytochrome c552 Gal_Lectin PF02140.18 OWF56022.1 - 5e-39 132.6 17.4 1.9e-21 76.3 3.3 3.4 3 1 0 3 3 3 2 Galactose binding lectin domain DUF3011 PF11218.8 OWF56022.1 - 3.9e-10 40.1 2.7 3.9e-10 40.1 2.7 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3011) DUF3395 PF11875.8 OWF56022.1 - 0.19 11.6 0.4 21 5.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3395) Na_Ca_ex PF01699.24 OWF56023.1 - 5.5e-55 185.5 44.1 1.3e-30 106.3 20.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TUDOR PF00567.24 OWF56024.1 - 2.5e-118 389.1 1.7 2.7e-28 98.4 0.0 5.4 5 0 0 5 5 5 5 Tudor domain Agenet PF05641.12 OWF56024.1 - 1.2e-14 54.5 2.1 0.019 15.4 0.0 5.9 5 0 0 5 5 5 4 Agenet domain RRM_1 PF00076.22 OWF56024.1 - 4.1e-09 36.1 0.0 1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4537 PF15057.6 OWF56024.1 - 2.5e-05 24.3 0.1 2.9 7.9 0.0 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF4537) zf-MYND PF01753.18 OWF56024.1 - 0.00014 21.8 20.1 0.00014 21.8 20.1 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 OWF56024.1 - 0.0021 17.9 13.2 0.0048 16.8 13.2 1.6 1 0 0 1 1 1 1 HIT zinc finger Tudor-knot PF11717.8 OWF56024.1 - 0.0032 17.3 0.1 7.1 6.6 0.0 4.8 5 0 0 5 5 5 1 RNA binding activity-knot of a chromodomain SH3_1 PF00018.28 OWF56024.1 - 0.054 13.1 0.1 34 4.2 0.0 3.6 3 0 0 3 3 3 0 SH3 domain 53-BP1_Tudor PF09038.10 OWF56024.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor NEMO PF11577.8 OWF56024.1 - 0.2 11.7 5.5 4.9 7.3 0.2 2.6 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO PPR_2 PF13041.6 OWF56025.1 - 1.3e-09 38.1 0.8 0.00068 19.8 0.1 3.5 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 OWF56025.1 - 2.6e-05 24.2 3.9 0.00051 20.1 0.5 3.7 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 OWF56025.1 - 0.0035 17.4 0.0 1.6 8.9 0.0 3.1 2 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 OWF56025.1 - 0.019 14.3 0.0 1.6 8.0 0.0 2.9 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP Prominin PF05478.11 OWF56026.1 - 9.3e-16 57.0 1.8 2.3 6.1 0.0 9.6 1 1 17 18 18 18 18 Prominin SH2 PF00017.24 OWF56027.1 - 6.7e-11 42.1 0.3 1.6e-10 40.9 0.2 1.7 2 0 0 2 2 2 1 SH2 domain FtsK_SpoIIIE_N PF12538.8 OWF56027.1 - 0.1 12.8 2.3 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 DNA transporter DUF4248 PF14053.6 OWF56028.1 - 2e-12 46.9 29.6 3.9 7.6 0.1 10.9 1 1 14 17 17 17 13 Domain of unknown function (DUF4248) EnY2 PF10163.9 OWF56028.1 - 2.3e-11 43.9 5.9 4 7.9 0.1 9.0 1 1 10 11 11 11 5 Transcription factor e(y)2 TIP39 PF14980.6 OWF56028.1 - 3.8e-09 36.3 21.0 2.8e+02 1.5 0.0 17.0 20 0 0 20 20 20 0 TIP39 peptide Peptidase_M16_M PF16187.5 OWF56028.1 - 0.011 15.1 0.0 43 3.3 0.0 5.8 1 1 2 4 4 4 0 Middle or third domain of peptidase_M16 HIPIP PF01355.17 OWF56028.1 - 1.2 9.5 8.6 3.3 8.1 0.3 5.3 2 1 6 9 9 9 0 High potential iron-sulfur protein Siva PF05458.12 OWF56029.1 - 0.28 10.9 6.9 0.64 9.7 6.9 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-B_box PF00643.24 OWF56029.1 - 1.4 9.1 14.7 0.069 13.3 8.0 2.3 3 0 0 3 3 3 0 B-box zinc finger Vps51 PF08700.11 OWF56030.1 - 4e-07 30.0 13.2 18 5.5 0.1 8.8 2 1 11 13 13 13 1 Vps51/Vps67 ATC_hydrolase PF14196.6 OWF56030.1 - 2.1e-06 28.6 0.0 4.1 8.2 0.0 4.6 1 1 3 4 4 4 2 L-2-amino-thiazoline-4-carboxylic acid hydrolase CNOT11 PF10155.9 OWF56030.1 - 4.7e-05 23.5 17.1 1.8e+04 -4.7 17.0 5.5 1 1 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 DUF2408 PF10303.9 OWF56030.1 - 0.14 12.7 9.8 29 5.2 1.6 4.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) HhH-GPD PF00730.25 OWF56030.1 - 0.59 10.6 16.3 1.2e+02 3.2 0.1 7.1 1 1 5 6 6 6 0 HhH-GPD superfamily base excision DNA repair protein TPR_7 PF13176.6 OWF56030.1 - 0.79 9.9 20.9 69 3.8 0.0 11.5 5 1 13 18 18 18 0 Tetratricopeptide repeat BCMA-Tall_bind PF09257.10 OWF56030.1 - 0.81 9.8 78.5 1.2e+02 2.8 0.0 20.4 2 2 20 22 22 22 0 BCMA, TALL-1 binding Coat_F PF07875.12 OWF56030.1 - 7.9 6.8 46.8 21 5.4 0.8 10.2 1 1 13 15 15 15 0 Coat F domain Hormone_recep PF00104.30 OWF56031.1 - 2.2e-18 66.6 0.8 4.8e-18 65.5 0.8 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor 7tm_1 PF00001.21 OWF56032.1 - 4.7e-35 121.2 21.7 6.3e-35 120.8 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF56032.1 - 0.00045 20.1 4.0 0.00045 20.1 4.0 2.7 2 1 0 2 2 2 1 Olfactory receptor Cyclin_N PF00134.23 OWF56034.1 - 7.5e-11 41.9 1.3 2.3e-09 37.1 0.3 2.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain Copine PF07002.16 OWF56035.1 - 4.4e-58 196.3 0.0 5.9e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 OWF56035.1 - 5e-12 46.4 0.1 9.7e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF749 PF05370.11 OWF56035.1 - 0.055 13.6 0.1 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF749) CotJA PF11007.8 OWF56035.1 - 0.17 11.7 0.2 0.4 10.5 0.2 1.6 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) Fez1 PF06818.15 OWF56036.1 - 0.0064 17.0 8.7 0.0064 17.0 8.7 5.6 1 1 4 5 5 5 2 Fez1 DHR10 PF18595.1 OWF56036.1 - 0.0071 16.4 17.7 0.0071 16.4 17.7 7.2 3 2 2 6 6 6 1 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 OWF56036.1 - 0.019 15.4 4.9 0.019 15.4 4.9 6.8 3 3 3 6 6 6 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 OWF56036.1 - 0.44 11.0 0.1 0.15 12.4 1.2 9.6 6 2 3 10 10 10 0 Flagella accessory protein C (FlaC) Mce4_CUP1 PF11887.8 OWF56036.1 - 0.54 9.7 8.4 1.4 8.4 3.3 2.5 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Uteroglobin PF01099.17 OWF56036.1 - 2.6 8.5 6.6 1.4 9.3 1.5 3.4 2 1 0 2 2 2 0 Uteroglobin family FUSC PF04632.12 OWF56036.1 - 4.2 5.8 24.2 2.2 6.7 9.0 2.7 1 1 2 3 3 3 0 Fusaric acid resistance protein family Lectin_C PF00059.21 OWF56037.1 - 0.13 13.0 0.8 0.13 13.0 0.8 1.9 2 0 0 2 2 2 0 Lectin C-type domain LPMO_10 PF03067.15 OWF56039.1 - 2.1e-12 48.1 0.3 2.1e-12 48.1 0.3 2.9 3 0 0 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Pentapeptide_2 PF01469.18 OWF56039.1 - 0.0035 17.2 20.3 0.28 11.1 9.2 3.3 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) CN_hydrolase PF00795.22 OWF56040.1 - 2.9e-14 53.0 0.0 7.4e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase AsnA PF03590.15 OWF56040.1 - 0.21 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase 7tm_2 PF00002.24 OWF56042.1 - 4.4e-20 72.0 17.2 3.6e-19 69.0 17.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) HTH_21 PF13276.6 OWF56043.1 - 0.16 12.1 2.9 0.19 11.9 0.2 2.1 2 0 0 2 2 2 0 HTH-like domain COesterase PF00135.28 OWF56045.1 - 2e-137 459.2 0.0 2.3e-137 459.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF56045.1 - 4.6e-07 29.9 0.7 1.6e-06 28.1 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3211 PF11485.8 OWF56045.1 - 0.0078 16.4 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3211) zf-C2H2 PF00096.26 OWF56046.1 - 7.5e-43 142.6 69.9 1.1e-06 28.7 1.4 9.9 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF56046.1 - 2.4e-31 106.7 58.1 5.7e-08 32.8 1.8 10.8 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF56046.1 - 7.5e-30 101.0 64.4 0.00054 20.6 1.0 9.9 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF56046.1 - 1.8e-09 37.6 41.8 0.0041 17.4 0.2 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OWF56046.1 - 2.6e-07 30.5 61.3 0.007 16.3 0.5 9.1 9 0 0 9 9 9 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OWF56046.1 - 8.3e-07 28.7 57.4 0.00052 19.7 2.4 8.2 8 2 0 8 8 8 5 C2H2-type zinc-finger domain GAGA PF09237.11 OWF56046.1 - 0.0004 20.1 17.9 0.052 13.4 0.2 5.4 3 1 2 5 5 5 2 GAGA factor zf-C2H2_11 PF16622.5 OWF56046.1 - 0.00047 19.8 56.2 0.07 12.9 0.2 9.4 10 0 0 10 10 10 3 zinc-finger C2H2-type zf-Di19 PF05605.12 OWF56046.1 - 0.00072 19.8 3.8 0.00072 19.8 3.8 4.9 3 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 OWF56046.1 - 0.011 16.0 34.2 0.62 10.4 9.9 5.5 2 1 4 6 6 6 0 C2H2-type zinc ribbon zf-BED PF02892.15 OWF56046.1 - 0.02 14.9 0.3 0.02 14.9 0.3 7.2 5 3 3 8 8 8 0 BED zinc finger Zn-ribbon_8 PF09723.10 OWF56046.1 - 0.038 14.1 45.5 0.24 11.5 0.2 8.1 5 1 4 9 9 9 0 Zinc ribbon domain zf-met PF12874.7 OWF56046.1 - 0.18 12.3 0.1 0.18 12.3 0.1 8.8 9 0 0 9 9 9 0 Zinc-finger of C2H2 type Trm112p PF03966.16 OWF56046.1 - 0.27 11.8 0.1 0.27 11.8 0.1 4.3 3 1 0 3 3 3 0 Trm112p-like protein PyrI_C PF02748.15 OWF56046.1 - 0.58 10.1 28.6 0.22 11.5 0.9 6.4 5 2 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HalOD2 PF18547.1 OWF56046.1 - 1.3 9.0 4.6 3.9 7.4 0.6 3.7 3 0 0 3 3 3 0 Halobacterial output domain 2 zf-LYAR PF08790.11 OWF56046.1 - 1.9 8.5 22.4 0.66 9.9 0.7 5.8 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger ERG2_Sigma1R PF04622.12 OWF56047.1 - 3.5e-41 140.9 0.7 4.8e-41 140.4 0.7 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ERG2_Sigma1R PF04622.12 OWF56048.1 - 4e-67 225.6 2.4 5.1e-67 225.3 2.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein YqcI_YcgG PF08892.11 OWF56049.1 - 9.5e-08 32.1 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 YqcI/YcgG family Alk_phosphatase PF00245.20 OWF56050.1 - 7e-134 446.9 1.3 8.2e-134 446.7 1.3 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OWF56050.1 - 9.5e-06 25.1 0.1 1.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OWF56050.1 - 0.0062 16.0 1.2 0.048 13.0 1.2 2.5 1 1 0 1 1 1 1 Sulfatase EMP24_GP25L PF01105.24 OWF56051.1 - 2.7e-28 99.1 3.3 3.2e-28 98.9 3.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CRT-like PF08627.10 OWF56053.1 - 1.3e-16 60.5 10.7 1.6e-15 56.9 10.7 2.0 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OWF56053.1 - 4.1 7.6 26.5 0.19 11.9 8.3 3.3 2 1 0 2 2 2 0 EamA-like transporter family Ycf4 PF02392.16 OWF56054.1 - 0.17 11.5 24.2 20 4.7 0.6 6.2 1 1 4 5 5 5 0 Ycf4 Mu-like_gpT PF10124.9 OWF56054.1 - 2.6 7.3 7.7 50 3.1 0.2 3.6 1 1 5 6 6 6 0 Mu-like prophage major head subunit gpT Benyvirus_P25 PF05744.11 OWF56054.1 - 4.4 6.5 12.9 44 3.3 0.4 4.8 1 1 5 6 6 6 0 Benyvirus P25/P26 protein Lectin_C PF00059.21 OWF56055.1 - 0.00061 20.5 0.1 0.0019 18.9 0.0 1.8 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 OWF56055.1 - 0.00078 19.4 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 PAN domain Sushi PF00084.20 OWF56055.1 - 0.001 19.6 1.2 0.0029 18.2 1.2 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) PAN_2 PF08276.11 OWF56055.1 - 0.057 13.5 0.4 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 PAN-like domain PRF PF06875.11 OWF56055.1 - 0.062 12.7 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Plethodontid receptivity factor PRF DHC_N1 PF08385.12 OWF56056.1 - 1.7e-179 598.1 16.9 1.7e-179 598.1 16.9 4.6 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 OWF56056.1 - 3.1e-175 582.2 9.2 6.8e-175 581.1 9.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 OWF56056.1 - 1.1e-152 507.8 0.0 1.5e-151 504.0 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OWF56056.1 - 7.3e-128 427.1 20.9 7.3e-128 427.1 20.9 5.5 5 2 2 7 7 7 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OWF56056.1 - 3.3e-98 328.7 0.1 1e-97 327.1 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OWF56056.1 - 4.7e-93 311.3 0.0 4.7e-93 311.3 0.0 2.2 3 0 0 3 3 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OWF56056.1 - 1.3e-84 282.7 0.3 5.1e-84 280.8 0.3 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 OWF56056.1 - 1.5e-74 249.4 0.7 1.2e-68 230.2 0.1 4.0 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OWF56056.1 - 3e-54 183.3 0.1 5.2e-53 179.2 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OWF56056.1 - 3.3e-44 149.2 2.0 5e-43 145.4 0.1 3.5 2 0 0 2 2 2 1 AAA+ lid domain Dynein_heavy PF03028.15 OWF56056.1 - 2.5e-38 130.8 0.0 6.3e-36 123.1 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OWF56056.1 - 4.1e-24 85.1 3.7 1.2e-23 83.6 1.8 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OWF56056.1 - 1.9e-21 76.5 0.0 1.4e-09 38.0 0.0 5.3 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF56056.1 - 1.8e-06 28.5 0.2 0.74 10.2 0.0 5.4 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 OWF56056.1 - 2.2e-05 24.7 0.1 4.3 7.6 0.0 4.8 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 OWF56056.1 - 0.00034 20.4 0.7 0.79 9.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain TrwB_AAD_bind PF10412.9 OWF56056.1 - 0.00058 18.9 0.4 0.087 11.7 0.0 3.2 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 OWF56056.1 - 0.00062 20.2 0.1 0.83 10.1 0.0 3.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OWF56056.1 - 0.004 17.5 0.5 0.61 10.4 0.0 3.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 OWF56056.1 - 0.0077 16.0 0.0 8.5 6.1 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain CbiA PF01656.23 OWF56056.1 - 0.012 15.6 0.1 0.25 11.4 0.0 3.2 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Roc PF08477.13 OWF56056.1 - 0.029 14.6 0.0 12 6.2 0.0 3.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OWF56056.1 - 0.044 14.2 0.5 93 3.5 0.0 4.6 4 0 0 4 4 3 0 RNA helicase Sigma54_activ_2 PF14532.6 OWF56056.1 - 0.07 13.2 0.1 0.93 9.6 0.0 3.1 3 0 0 3 3 1 0 Sigma-54 interaction domain T2SSE PF00437.20 OWF56056.1 - 0.07 12.2 0.0 0.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2451 PF10474.9 OWF56056.1 - 0.078 12.8 4.3 3.1 7.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2451) AAA_18 PF13238.6 OWF56056.1 - 0.14 12.7 1.6 3.9 8.0 0.0 4.3 4 0 0 4 4 2 0 AAA domain ATP_bind_1 PF03029.17 OWF56056.1 - 1.2 8.9 5.9 0.57 9.9 0.0 3.7 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Plk4_PB2 PF18409.1 OWF56056.1 - 6.7 7.4 11.4 0.5 11.1 0.1 4.8 5 0 0 5 5 2 0 Polo-like Kinase 4 Polo Box 2 DUF4208 PF13907.6 OWF56056.1 - 9.5 6.7 9.4 13 6.3 0.9 5.6 5 0 0 5 5 3 0 Domain of unknown function (DUF4208) PLDc_2 PF13091.6 OWF56057.1 - 1.5e-14 54.0 0.1 8e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OWF56057.1 - 0.0002 21.4 3.1 0.0016 18.5 0.1 2.7 2 1 0 2 2 2 1 Phospholipase D Active site motif RE_NgoFVII PF09565.10 OWF56057.1 - 0.02 14.2 0.5 0.41 9.9 0.1 2.7 3 0 0 3 3 3 0 NgoFVII restriction endonuclease PI-PLC-X PF00388.19 OWF56058.1 - 0.24 11.0 3.8 17 5.0 0.1 4.0 3 2 2 5 5 5 0 Phosphatidylinositol-specific phospholipase C, X domain Fz PF01392.22 OWF56058.1 - 0.63 10.7 15.8 2.4 8.8 1.4 4.4 1 1 0 2 2 2 0 Fz domain DUF1353 PF07087.11 OWF56059.1 - 0.0085 15.8 5.6 8.4 6.2 0.1 4.0 1 1 3 4 4 4 3 Protein of unknown function (DUF1353) Trypsin_2 PF13365.6 OWF56059.1 - 0.25 12.2 6.0 1.6e+02 3.2 5.5 3.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain EGF_3 PF12947.7 OWF56059.1 - 3.2 8.0 16.7 19 5.6 1.5 5.0 2 1 3 5 5 5 0 EGF domain Cornifin PF02389.15 OWF56060.1 - 0.084 13.1 0.7 1.7 8.9 0.0 2.3 2 1 0 2 2 2 0 Cornifin (SPRR) family DUF5305 PF17231.2 OWF56061.1 - 0.011 15.2 2.7 0.02 14.3 2.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Glycophorin_A PF01102.18 OWF56061.1 - 0.018 15.3 1.9 0.052 13.8 0.4 2.5 2 0 0 2 2 2 0 Glycophorin A Podoplanin PF05808.11 OWF56061.1 - 0.035 14.2 10.6 0.07 13.2 10.6 1.5 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 OWF56061.1 - 0.097 13.6 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 OWF56061.1 - 0.14 12.0 3.8 0.22 11.3 3.0 1.8 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor RIFIN PF02009.16 OWF56061.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Rifin Lectin_C PF00059.21 OWF56061.1 - 0.35 11.6 5.6 1.4 9.7 0.2 3.4 2 2 1 3 3 3 0 Lectin C-type domain Adeno_E3_CR2 PF02439.15 OWF56061.1 - 0.7 9.7 4.0 1.2 9.0 4.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 OWF56061.1 - 0.81 9.2 5.7 2 7.9 5.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 OWF56061.1 - 1.1 9.2 3.1 2.4 8.1 3.1 1.5 1 0 0 1 1 1 0 Syndecan domain Pex14_N PF04695.13 OWF56061.1 - 5.4 7.6 17.3 0.044 14.4 1.7 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Endonuclease_7 PF02945.15 OWF56062.1 - 0.00018 21.4 1.2 0.00018 21.4 1.2 2.0 2 0 0 2 2 2 1 Recombination endonuclease VII FYVE PF01363.21 OWF56062.1 - 0.093 12.9 4.5 0.37 10.9 1.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger zf-C2H2_8 PF15909.5 OWF56062.1 - 0.11 12.8 0.9 0.39 11.1 0.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon Pkinase PF00069.25 OWF56063.1 - 2.3e-64 217.3 0.0 2.7e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56063.1 - 3.2e-33 115.1 0.0 3.7e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF56063.1 - 1e-05 25.6 0.1 0.00049 20.1 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OWF56063.1 - 0.00035 20.0 0.1 0.00091 18.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OWF56063.1 - 0.00054 19.0 0.0 0.00096 18.2 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OWF56063.1 - 0.0012 18.5 0.0 0.0063 16.1 0.0 2.0 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 OWF56063.1 - 0.0028 17.0 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OWF56063.1 - 0.14 11.8 0.1 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ACBP PF00887.19 OWF56064.1 - 1.3e-25 89.4 0.7 2.4e-25 88.6 0.7 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2489 PF10675.9 OWF56064.1 - 0.2 11.6 1.8 0.19 11.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) EGF PF00008.27 OWF56065.1 - 1.9e-09 37.6 18.7 8e-06 26.1 6.2 3.8 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 OWF56065.1 - 0.0044 17.6 18.2 0.029 15.0 1.2 3.4 3 0 0 3 3 3 2 Human growth factor-like EGF AKNA PF12443.8 OWF56065.1 - 0.0068 17.0 0.6 0.96 10.1 0.0 2.8 2 0 0 2 2 2 1 AT-hook-containing transcription factor EGF_CA PF07645.15 OWF56065.1 - 0.0095 16.1 4.1 0.0095 16.1 4.1 3.1 3 1 1 4 4 4 2 Calcium-binding EGF domain FDX-ACB PF03147.14 OWF56065.1 - 0.019 15.4 0.6 0.058 13.8 0.7 1.7 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain EGF_3 PF12947.7 OWF56065.1 - 0.019 15.1 12.1 0.24 11.6 4.0 2.8 1 1 1 2 2 2 0 EGF domain DUF1018 PF06252.12 OWF56065.1 - 0.03 15.3 2.9 0.51 11.3 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Laminin_EGF PF00053.24 OWF56065.1 - 0.11 12.7 16.8 1 9.5 4.2 2.9 1 1 1 2 2 2 0 Laminin EGF domain DUF2407_C PF13373.6 OWF56065.1 - 1.6 8.9 3.3 23 5.2 0.0 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain Homeodomain PF00046.29 OWF56066.1 - 2.1e-22 78.7 2.6 3.5e-22 78.0 2.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF56066.1 - 0.088 12.7 0.7 0.6 10.1 0.0 2.7 3 0 0 3 3 3 0 Homeobox KN domain HTH_50 PF18024.1 OWF56066.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Homeodomain PF00046.29 OWF56067.1 - 1.7e-20 72.6 6.0 2.6e-20 72.0 6.0 1.3 1 0 0 1 1 1 1 Homeodomain C1q PF00386.21 OWF56068.1 - 1.2e-23 83.7 0.5 1.5e-23 83.4 0.5 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 OWF56068.1 - 0.0001 21.9 9.2 0.00018 21.2 9.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Aminotran_1_2 PF00155.21 OWF56069.1 - 1e-49 169.6 0.0 1.3e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OWF56069.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 OWF56069.1 - 0.095 11.3 0.0 0.36 9.4 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-III RNA_pol_N PF01194.17 OWF56069.1 - 0.11 12.9 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Aminotran_1_2 PF00155.21 OWF56070.1 - 2.4e-49 168.5 0.0 2.9e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Blt1_C PF17183.4 OWF56070.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Get5 carboxyl domain Beta_elim_lyase PF01212.21 OWF56070.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 OWF56070.1 - 0.081 11.6 0.0 0.16 10.6 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-III AMP-binding PF00501.28 OWF56071.1 - 4.4e-69 233.1 0.0 5.4e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF56071.1 - 0.017 16.1 0.0 0.049 14.6 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Lectin_C PF00059.21 OWF56072.1 - 2.2e-15 57.3 0.8 3e-15 56.9 0.8 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF56072.1 - 0.0065 16.1 1.2 0.011 15.4 1.2 1.6 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Antimicrobial14 PF08109.11 OWF56072.1 - 0.032 14.2 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Lactocin 705 family Lectin_C PF00059.21 OWF56073.1 - 3e-16 60.1 2.4 4e-16 59.7 2.4 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF56073.1 - 0.00042 20.0 3.7 0.0029 17.3 3.7 2.0 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF56073.1 - 0.057 12.7 0.2 0.1 11.9 0.1 1.5 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Xlink PF00193.17 OWF56073.1 - 0.21 12.0 6.4 0.27 11.6 0.3 2.6 2 1 1 3 3 3 0 Extracellular link domain Lectin_C PF00059.21 OWF56074.1 - 1.2e-16 61.4 3.7 1.5e-16 61.0 3.7 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 OWF56074.1 - 0.00033 20.4 1.2 0.00036 20.2 1.2 1.2 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 OWF56074.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein NlpE PF04170.12 OWF56074.1 - 0.1 13.6 0.0 0.16 13.0 0.0 1.3 1 0 0 1 1 1 0 NlpE N-terminal domain DUF3432 PF11914.8 OWF56075.1 - 0.16 12.3 7.7 0.27 11.5 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Methyltransf_22 PF13383.6 OWF56076.1 - 8e-11 42.0 0.0 9.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 OWF56076.1 - 0.0017 18.4 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF4950 PF16308.5 OWF56077.1 - 0.016 15.2 9.3 3.4 7.6 2.6 4.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4950) Tim17 PF02466.19 OWF56078.1 - 0.0039 17.5 0.0 1.1 9.6 0.0 2.8 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family HSP70 PF00012.20 OWF56079.1 - 2.8e-15 55.5 0.2 3.8e-13 48.5 0.2 2.2 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 OWF56079.1 - 0.0023 17.5 0.0 0.0063 16.0 0.0 1.7 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Sulfotransfer_2 PF03567.14 OWF56080.1 - 3.3e-23 82.9 1.6 8.4e-18 65.2 0.0 2.8 3 0 0 3 3 3 2 Sulfotransferase family DAGK_acc PF00609.19 OWF56082.1 - 9.9e-46 156.0 0.0 2.3e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OWF56082.1 - 1.5e-26 92.5 0.0 2.7e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 OWF56082.1 - 2.3e-11 43.4 24.2 2.7e-11 43.2 13.2 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 OWF56082.1 - 1.6 8.7 6.2 0.65 10.0 2.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 OWF56082.1 - 7.4 6.6 10.8 7.1 6.6 0.4 2.9 2 0 0 2 2 2 0 PHD-finger ADK_lid PF05191.14 OWF56082.1 - 8.6 6.4 8.3 2.6 8.1 0.1 3.3 4 0 0 4 4 4 0 Adenylate kinase, active site lid MerT PF02411.15 OWF56083.1 - 7.5 6.6 14.1 52 3.9 0.3 4.0 1 1 3 5 5 5 0 MerT mercuric transport protein CobU PF02283.16 OWF56083.1 - 8.9 5.8 17.2 22 4.6 1.2 5.1 1 1 3 5 5 5 0 Cobinamide kinase / cobinamide phosphate guanyltransferase EGF_CA PF07645.15 OWF56084.1 - 8.1e-07 29.1 9.0 8.1e-07 29.1 9.0 5.3 4 3 1 5 5 5 1 Calcium-binding EGF domain EGF_3 PF12947.7 OWF56084.1 - 0.0052 17.0 1.1 0.0052 17.0 1.1 4.8 4 0 0 4 4 4 2 EGF domain SEA PF01390.20 OWF56084.1 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 SEA domain TarS_C1 PF18674.1 OWF56084.1 - 0.016 15.1 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 Chordopox_A13L PF05961.11 OWF56084.1 - 0.074 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein MAP17 PF15807.5 OWF56084.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RNA_pol_I_TF PF04090.12 OWF56085.1 - 6.6e-07 29.0 2.3 5.5 6.4 0.0 5.1 1 1 2 5 5 5 4 RNA polymerase I specific initiation factor BssC_TutF PF08201.11 OWF56085.1 - 3.7 7.6 6.8 1.1e+02 2.9 0.1 4.3 1 1 3 5 5 5 0 BssC/TutF protein GKAP PF03359.13 OWF56086.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Cytokin-bind PF09265.10 OWF56087.1 - 0.0014 18.1 3.6 2.7 7.3 0.6 3.8 1 1 2 3 3 3 2 Cytokinin dehydrogenase 1, FAD and cytokinin binding Dockerin_1 PF00404.18 OWF56087.1 - 0.0035 17.5 0.3 3 8.1 0.0 3.7 2 1 1 3 3 3 1 Dockerin type I domain Med31 PF05669.12 OWF56087.1 - 0.0097 15.9 3.5 0.23 11.5 3.5 2.2 1 1 0 1 1 1 1 SOH1 MitoNEET_N PF10660.9 OWF56087.1 - 0.024 14.7 3.6 4.1 7.5 0.3 3.7 1 1 1 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Cro PF09048.10 OWF56087.1 - 3.6 7.7 7.5 1.1e+02 2.9 0.0 4.5 4 1 1 5 5 5 0 Cro DUF1706 PF08020.11 OWF56087.1 - 4.3 7.2 7.3 25 4.8 1.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1706) MitoNEET_N PF10660.9 OWF56088.1 - 0.0011 18.9 3.0 2 8.5 0.0 3.2 1 1 1 3 3 3 2 Iron-containing outer mitochondrial membrane protein N-terminus FAD_syn PF06574.12 OWF56088.1 - 0.065 13.1 0.2 9.6 6.1 0.0 2.3 1 1 2 3 3 3 0 FAD synthetase Med31 PF05669.12 OWF56088.1 - 0.14 12.2 9.9 22 5.1 9.9 2.3 1 1 0 1 1 1 0 SOH1 Protoglobin PF11563.8 OWF56088.1 - 0.24 11.3 5.6 0.3 10.9 1.8 2.2 1 1 1 2 2 2 0 Protoglobin MotB_plug PF13677.6 OWF56088.1 - 0.65 9.6 6.9 1.8 8.2 0.2 3.4 3 0 0 3 3 3 0 Membrane MotB of proton-channel complex MotA/MotB Cro PF09048.10 OWF56088.1 - 1.1 9.4 5.3 1.1e+02 2.9 0.0 4.6 4 2 3 7 7 7 0 Cro Neur_chan_LBD PF02931.23 OWF56089.1 - 4.3e-34 117.9 1.6 6.5e-34 117.3 1.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF56089.1 - 2.3e-16 60.6 0.1 3.7e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF56090.1 - 2.1e-30 105.8 0.8 2.1e-30 105.8 0.8 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF56090.1 - 2.1e-17 64.0 0.2 3.8e-17 63.1 0.2 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 OWF56091.1 - 2.1e-34 118.9 0.5 3.4e-34 118.2 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF56091.1 - 8e-16 58.8 0.1 1.4e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Abi_HHR PF07815.14 OWF56092.1 - 1.6e-29 101.9 0.5 3.8e-29 100.7 0.5 1.7 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.6 OWF56092.1 - 7.3e-16 57.8 0.5 1.4e-15 56.9 0.5 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF56092.1 - 3e-15 55.5 0.4 5.1e-15 54.8 0.4 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OWF56092.1 - 1.4e-11 43.9 0.0 2.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SRP68 PF16969.5 OWF56092.1 - 0.0068 15.5 1.7 0.009 15.1 1.7 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF4922 PF16269.5 OWF56092.1 - 0.28 10.9 3.7 0.73 9.6 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) DUF3450 PF11932.8 OWF56092.1 - 2.5 7.3 6.2 3.9 6.7 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-RING_UBOX PF13445.6 OWF56093.1 - 2.1e-06 27.7 5.7 2.1e-06 27.7 5.7 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OWF56093.1 - 9.6e-06 25.4 13.2 9.6e-06 25.4 13.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF56093.1 - 2.6e-05 24.3 12.1 2.6e-05 24.3 12.1 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 OWF56093.1 - 0.00015 21.8 8.0 0.00015 21.8 8.0 3.4 2 1 0 2 2 2 1 B-box zinc finger zf-RING_2 PF13639.6 OWF56093.1 - 0.0011 19.3 11.6 0.0011 19.3 11.6 3.0 3 0 0 3 3 3 1 Ring finger domain NHL PF01436.21 OWF56093.1 - 0.0014 18.5 0.1 1.4 9.1 0.0 3.6 3 0 0 3 3 3 1 NHL repeat zf-RING_5 PF14634.6 OWF56093.1 - 0.0058 16.6 14.8 0.0058 16.6 14.8 3.5 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF56093.1 - 0.0069 16.2 11.8 0.0069 16.2 11.8 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DASH_Dad1 PF08649.10 OWF56093.1 - 0.36 11.1 2.1 0.93 9.7 2.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad1 MLD PF11647.8 OWF56093.1 - 2.1 8.7 4.8 3.1 8.1 0.9 2.5 2 0 0 2 2 2 0 Membrane Localization Domain TRM PF02005.16 OWF56094.1 - 2.2e-33 115.9 0.1 9.5e-29 100.7 0.2 2.2 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase RRM_1 PF00076.22 OWF56095.1 - 3.8e-12 45.9 0.0 1.5e-11 43.9 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GalP_UDP_tr_C PF02744.17 OWF56095.1 - 0.062 13.0 0.1 0.088 12.5 0.1 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain RRF PF01765.19 OWF56096.1 - 2.8e-28 98.9 11.2 2.8e-28 98.9 11.2 1.8 1 1 1 2 2 2 1 Ribosome recycling factor COBRA1 PF06209.13 OWF56096.1 - 0.049 12.5 5.3 0.063 12.1 5.3 1.1 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) DcrB PF08786.11 OWF56096.1 - 5 7.2 10.5 0.58 10.2 2.4 2.2 1 1 1 2 2 2 0 DcrB Urm1 PF09138.11 OWF56097.1 - 5.4e-38 129.2 0.0 6e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 OWF56097.1 - 0.00065 20.3 0.0 0.00071 20.2 0.0 1.2 1 0 0 1 1 1 1 ThiS family KAP PF05804.12 OWF56098.1 - 0 1236.1 26.8 0 1235.9 26.8 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 OWF56098.1 - 3.2e-08 33.3 4.1 0.21 11.7 0.2 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 OWF56098.1 - 0.0028 17.4 1.7 0.0098 15.6 0.0 2.7 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain NopRA1 PF16201.5 OWF56098.1 - 0.11 12.1 3.3 12 5.4 0.1 3.5 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 FPL PF09758.9 OWF56098.1 - 0.21 11.6 13.5 0.56 10.2 6.1 3.8 3 1 0 3 3 3 0 Uncharacterised conserved protein FoP_duplication PF13865.6 OWF56098.1 - 0.61 10.7 4.4 1.3 9.7 4.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 V-ATPase_H_C PF11698.8 OWF56098.1 - 8 6.6 10.6 0.5 10.5 0.7 3.6 4 1 1 5 5 5 0 V-ATPase subunit H Methyltransf_PK PF05891.12 OWF56099.1 - 2.5e-79 265.9 0.0 3.1e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OWF56099.1 - 1.1e-06 29.3 0.0 2.7e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF56099.1 - 0.00024 21.7 0.0 0.00041 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OWF56099.1 - 0.0034 16.7 0.1 0.0055 16.0 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OWF56099.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ANAPC_CDC26 PF10471.9 OWF56102.1 - 2.1e-10 41.3 3.9 2.3e-10 41.1 3.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Ter PF05472.11 OWF56102.1 - 0.037 13.1 0.1 0.039 13.0 0.1 1.0 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) WD40 PF00400.32 OWF56103.1 - 5.8e-46 153.5 12.1 8.8e-09 35.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 OWF56103.1 - 2e-14 52.8 0.3 3.9e-14 51.9 0.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 OWF56103.1 - 2.7e-13 50.0 0.0 0.0024 18.1 0.0 5.3 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OWF56103.1 - 1.2e-05 24.2 0.0 0.16 10.6 0.0 4.2 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OWF56103.1 - 1.9e-05 23.8 0.6 0.42 9.5 0.2 3.9 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OWF56103.1 - 0.00073 19.0 0.0 0.048 13.0 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain MMS1_N PF10433.9 OWF56103.1 - 0.013 14.2 0.0 3.7 6.1 0.0 2.3 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2475 PF10629.9 OWF56104.1 - 6.1e-29 100.0 11.4 4.7e-10 39.5 0.5 4.4 4 0 0 4 4 4 4 Protein of unknown function (DUF2475) Ank_2 PF12796.7 OWF56105.1 - 1.2e-20 73.9 3.3 6.7e-08 33.0 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF56105.1 - 3.6e-16 59.3 0.5 2.8e-05 24.6 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OWF56105.1 - 1.9e-14 53.3 1.6 0.0001 22.6 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 OWF56105.1 - 9.3e-14 50.2 2.6 0.00012 22.2 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ion_trans PF00520.31 OWF56105.1 - 5.1e-11 42.3 27.5 8.6e-11 41.5 27.3 1.5 1 1 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 OWF56105.1 - 5.3e-11 42.5 0.9 1.1e-05 25.7 0.2 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PKD_channel PF08016.12 OWF56105.1 - 3.9e-06 25.8 11.6 3.9e-06 25.8 11.6 1.8 1 1 0 1 1 1 1 Polycystin cation channel OmpH PF03938.14 OWF56105.1 - 6.7 7.1 12.4 6.8 7.0 8.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Innexin PF00876.18 OWF56106.1 - 3.9e-55 187.5 7.1 4.7e-55 187.3 7.1 1.1 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 OWF56107.1 - 1.2e-61 209.0 2.3 1.4e-61 208.7 2.3 1.0 1 0 0 1 1 1 1 Innexin PhyH PF05721.13 OWF56108.1 - 4.8e-31 108.7 0.0 9.3e-31 107.7 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 OWF56109.1 - 6.9e-07 29.7 0.0 1.4e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3456 PF11938.8 OWF56109.1 - 0.076 13.5 0.0 0.091 13.3 0.0 1.2 1 1 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP PhyH PF05721.13 OWF56110.1 - 1.8e-31 110.1 0.0 2.3e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OWF56110.1 - 0.025 15.0 0.2 0.055 13.9 0.0 1.7 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.12 OWF56110.1 - 0.039 12.7 0.3 0.98 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 OWF56110.1 - 0.049 14.5 0.0 0.093 13.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 OWF56111.1 - 1.2e-31 110.7 0.0 1.8e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 OWF56111.1 - 0.011 16.6 0.0 0.027 15.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ATAD4 PF15321.6 OWF56112.1 - 0.00063 21.0 15.8 0.0008 20.7 10.3 2.8 2 1 0 2 2 2 1 ATPase family AAA domain containing 4 TSP_1 PF00090.19 OWF56113.1 - 1.3e-15 57.3 221.1 2.1e-08 34.3 5.7 22.2 22 1 0 22 22 22 15 Thrombospondin type 1 domain DNA_methylase PF00145.17 OWF56116.1 - 2.9e-51 174.8 0.0 2.9e-51 174.8 0.0 2.4 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 OWF56116.1 - 6.9e-39 133.2 0.0 2.4e-38 131.4 0.0 2.0 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 OWF56116.1 - 6.7e-32 109.9 0.6 1.6e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 BAH domain DMAP_binding PF06464.11 OWF56116.1 - 2.2e-11 44.5 6.3 3.9e-09 37.3 0.7 4.6 4 1 1 5 5 5 2 DMAP1-binding Domain zf-CXXC PF02008.20 OWF56116.1 - 1e-08 35.1 10.6 1e-08 35.1 10.6 2.8 3 0 0 3 3 3 1 CXXC zinc finger domain GvpG PF05120.12 OWF56116.1 - 0.036 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Gas vesicle protein G SecE PF00584.20 OWF56117.1 - 4e-17 61.9 0.1 5e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Cupin_8 PF13621.6 OWF56118.1 - 1.2e-34 120.2 0.1 2.9e-34 118.9 0.1 1.7 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OWF56118.1 - 4e-11 43.0 0.2 1.5e-10 41.0 0.2 1.8 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OWF56118.1 - 2.5e-07 31.1 0.3 1.2e-06 29.0 0.3 2.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OWF56118.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Rcd1 PF04078.13 OWF56119.1 - 1.7e-132 440.5 0.5 2e-132 440.3 0.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Macro PF01661.21 OWF56119.1 - 0.091 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Macro domain TIR_2 PF13676.6 OWF56120.1 - 2.1e-09 38.0 0.0 7.5e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 OWF56120.1 - 2.7e-07 30.6 0.0 1.7e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF56121.1 - 5e-10 40.0 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain Death PF00531.22 OWF56121.1 - 2.7e-07 30.7 0.0 7.1e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Death domain TIR PF01582.20 OWF56121.1 - 1.1e-06 28.6 0.0 1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 TIR domain HsdM_N PF12161.8 OWF56123.1 - 0.037 14.7 4.0 0.043 14.4 4.0 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain TMPIT PF07851.13 OWF56123.1 - 0.23 10.7 3.8 0.25 10.5 3.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF3552 PF12072.8 OWF56123.1 - 0.37 10.2 11.6 0.43 10.0 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Nup153 PF08604.10 OWF56123.1 - 0.64 8.7 2.5 0.71 8.6 2.5 1.0 1 0 0 1 1 1 0 Nucleoporin Nup153-like Pkinase PF00069.25 OWF56124.1 - 5e-39 134.3 0.0 8.7e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56124.1 - 4.4e-37 127.8 0.0 6.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.22 OWF56124.1 - 0.00074 19.6 0.2 0.02 15.0 0.0 3.2 2 1 1 3 3 3 1 Death domain Death_2 PF14786.6 OWF56124.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Tube Death domain Kinase-like PF14531.6 OWF56124.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pou PF00157.17 OWF56125.1 - 4.3e-29 100.3 0.1 1.1e-28 99.0 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 OWF56125.1 - 2.1e-16 59.5 1.3 2.1e-16 59.5 1.3 1.9 2 0 0 2 2 2 1 Homeodomain HOCHOB PF17943.1 OWF56125.1 - 0.013 16.2 0.0 0.024 15.4 0.0 1.4 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox HTH_31 PF13560.6 OWF56125.1 - 0.038 14.3 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Homeobox_KN PF05920.11 OWF56125.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain YscW PF09619.10 OWF56126.1 - 8.5e-08 32.5 3.6 63 4.0 0.0 10.6 3 3 12 15 15 15 1 Type III secretion system lipoprotein chaperone (YscW) Tnp_22_dsRBD PF17490.2 OWF56126.1 - 0.0031 17.5 38.5 35 4.5 0.0 14.7 7 7 10 18 18 18 3 L1 transposable element dsRBD-like domain Cytokin_check_N PF10407.9 OWF56127.1 - 5.6e-05 23.0 21.1 9.9 6.2 0.4 16.3 11 7 11 24 24 24 1 Cdc14 phosphatase binding protein N-terminus Toxin_19 PF08088.12 OWF56128.1 - 0.00013 22.0 0.8 1e+02 3.2 0.0 5.3 5 0 0 5 5 5 0 Conotoxin I-superfamily Pentapeptide_2 PF01469.18 OWF56128.1 - 0.51 10.3 7.8 17 5.4 0.9 4.2 3 1 0 3 3 3 0 Pentapeptide repeats (8 copies) Pentapeptide_2 PF01469.18 OWF56129.1 - 3.1e-07 30.2 16.6 0.61 10.0 0.3 6.6 3 1 4 8 8 8 5 Pentapeptide repeats (8 copies) HHH_8 PF14716.6 OWF56129.1 - 0.59 10.5 6.3 1.1e+02 3.2 0.2 5.2 1 1 2 3 3 3 0 Helix-hairpin-helix domain SpoIISB_antitox PF14185.6 OWF56129.1 - 2.3 8.1 10.8 9.3 6.2 0.0 5.3 3 2 5 8 8 8 0 Antitoxin SpoIISB, type II toxin-antitoxin system zf-C4 PF00105.18 OWF56130.1 - 5.6e-19 68.4 12.0 1.2e-16 60.9 12.0 2.4 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 OWF56130.1 - 1.3e-11 44.5 0.6 1.3e-11 44.5 0.6 2.0 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor ENTH PF01417.20 OWF56130.1 - 0.13 12.3 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 ENTH domain DUF3045 PF11243.8 OWF56131.1 - 4.2e-05 23.6 0.1 2.6 8.2 0.0 4.4 1 1 2 3 3 3 2 Protein of unknown function (DUF3045) Luciferase_3H PF10284.9 OWF56131.1 - 0.00044 20.4 1.9 6.8 6.9 0.0 4.4 2 1 4 6 6 6 3 Luciferase helical bundle domain MIP-T3 PF10243.9 OWF56131.1 - 0.082 12.9 14.7 9.2 6.3 1.1 5.6 1 1 3 5 5 5 0 Microtubule-binding protein MIP-T3 CH-like domain SAND PF01342.21 OWF56131.1 - 0.092 12.5 0.2 36 4.2 0.0 3.7 5 1 0 5 5 5 0 SAND domain Phostensin_N PF13916.6 OWF56132.1 - 2.9e-15 56.4 0.0 6.4 7.2 0.0 7.8 1 1 13 15 15 15 11 PP1-regulatory protein, Phostensin N-terminal Ndufs5 PF10200.9 OWF56132.1 - 8.8e-14 51.5 0.1 49 4.3 0.0 11.5 1 1 15 16 16 16 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Gp_UL130 PF11668.8 OWF56132.1 - 1.5e-06 28.3 1.4 9.9 6.1 0.0 8.3 1 1 11 14 14 14 1 HCMV glycoprotein pUL130 DUF4824 PF16106.5 OWF56132.1 - 7.9e-06 25.3 0.0 5.3 6.2 0.0 5.3 1 1 7 8 8 8 2 Domain of unknown function (DUF4824) OKR_DC_1 PF01276.20 OWF56132.1 - 0.0026 16.6 22.5 2 7.0 0.4 8.1 1 1 10 11 11 11 1 Orn/Lys/Arg decarboxylase, major domain fn3_PAP PF17808.1 OWF56132.1 - 0.02 15.0 13.5 27 4.9 0.9 7.9 2 2 2 4 4 4 0 Fn3-like domain from Purple Acid Phosphatase Cthe_2159 PF14262.6 OWF56132.1 - 0.086 12.2 0.1 11 5.2 0.0 3.2 2 1 1 3 3 3 0 Carbohydrate-binding domain-containing protein Cthe_2159 ATAD4 PF15321.6 OWF56132.1 - 1.2 10.5 15.2 40 5.7 0.2 7.0 1 1 2 4 4 4 0 ATPase family AAA domain containing 4 DUF2358 PF10184.9 OWF56133.1 - 0.051 13.9 0.0 15 5.9 0.0 3.2 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2358) Amido_AtzD_TrzD PF09663.10 OWF56133.1 - 0.14 11.1 0.0 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) HBM PF16591.5 OWF56134.1 - 0.076 12.4 0.0 52 3.1 0.0 3.8 1 1 4 5 5 5 0 Helical bimodular sensor domain Keratin_2_tail PF16210.5 OWF56134.1 - 0.91 9.8 41.8 3.9 7.8 13.1 3.0 1 1 1 2 2 2 0 Keratin type II cytoskeletal 1 tail MarB PF13999.6 OWF56137.1 - 0.099 12.5 6.3 0.81 9.6 0.5 3.3 1 1 2 3 3 3 0 MarB protein DUF1249 PF06853.12 OWF56137.1 - 0.14 12.1 5.1 2.5 8.1 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1249) Mucin15 PF15672.5 OWF56137.1 - 0.56 9.6 8.9 0.67 9.4 8.9 1.0 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 CTD PF12815.7 OWF56138.1 - 7.1e-06 26.5 79.6 0.048 14.2 9.0 8.5 1 1 3 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 API5 PF05918.11 OWF56138.1 - 0.28 10.0 0.0 3.5 6.3 0.0 2.6 1 1 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) PGBA_N PF15436.6 OWF56138.1 - 0.52 9.9 8.6 7.5 6.1 0.1 4.1 3 1 0 4 4 4 0 Plasminogen-binding protein pgbA N-terminal LAS2 PF15792.5 OWF56139.1 - 0.024 15.1 20.1 1.3e+02 3.2 0.1 10.0 1 1 14 15 15 15 0 Lung adenoma susceptibility protein 2 ETF PF01012.21 OWF56140.1 - 2.8e-44 151.2 2.0 3.9e-44 150.7 2.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OWF56140.1 - 3.8e-36 123.0 1.3 5.3e-36 122.5 0.2 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain RINGv PF12906.7 OWF56141.1 - 6e-05 23.1 0.9 0.00017 21.7 0.9 1.8 1 0 0 1 1 1 1 RING-variant domain Galactosyl_T PF01762.21 OWF56142.1 - 8.8e-28 97.5 0.7 1e-27 97.2 0.7 1.0 1 0 0 1 1 1 1 Galactosyltransferase Glycos_transf_2 PF00535.26 OWF56142.1 - 0.036 13.9 0.5 0.06 13.2 0.5 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 2 Cas_Cmr5 PF09701.10 OWF56142.1 - 0.059 13.7 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) DUF836 PF05768.14 OWF56143.1 - 4e-14 52.8 0.1 5.2e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 OWF56143.1 - 8.4e-05 22.7 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin MFS_1 PF07690.16 OWF56144.1 - 1.9e-06 27.1 27.3 8.5e-06 24.9 27.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2964 PF11177.8 OWF56144.1 - 0.026 14.7 5.8 0.58 10.4 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) Radial_spoke PF04712.12 OWF56144.1 - 0.039 12.9 0.0 0.039 12.9 0.0 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein Trp_oprn_chp PF09534.10 OWF56144.1 - 0.28 11.0 1.5 2.5 7.9 0.0 2.5 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM51 PF15345.6 OWF56144.1 - 0.75 9.6 2.7 0.87 9.4 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 TRAP_alpha PF03896.16 OWF56144.1 - 3 7.0 5.3 1.2 8.3 1.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit MFS_1 PF07690.16 OWF56145.1 - 8.8e-07 28.2 37.6 0.0055 15.7 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-met PF12874.7 OWF56146.1 - 3.7e-05 24.0 23.5 0.0046 17.3 0.7 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OWF56146.1 - 0.0011 19.3 39.0 0.19 12.2 0.8 7.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF56146.1 - 0.009 16.8 42.9 0.089 13.7 0.6 7.3 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OWF56146.1 - 0.17 12.6 12.6 8.6 7.0 0.6 4.0 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_aberr PF17017.5 OWF56146.1 - 0.38 10.9 9.2 0.75 9.9 0.2 3.5 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C3HC4_3 PF13920.6 OWF56147.1 - 2.5e-11 43.3 12.1 4.1e-11 42.6 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF56147.1 - 1.5e-05 24.7 12.0 1.5e-05 24.7 12.0 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OWF56147.1 - 0.00041 20.2 11.9 0.00086 19.1 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF56147.1 - 0.011 15.7 14.2 0.011 15.7 14.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OWF56147.1 - 0.013 15.3 13.8 0.038 13.8 13.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF56147.1 - 0.029 14.4 12.3 0.061 13.4 7.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 OWF56147.1 - 0.15 12.4 16.6 0.074 13.4 14.5 1.6 2 0 0 2 2 2 0 Ring finger domain Baculo_IE-1 PF05290.11 OWF56147.1 - 0.21 11.5 3.9 0.32 10.9 3.9 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 OWF56147.1 - 3.8 7.7 11.4 10 6.4 11.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING rve PF00665.26 OWF56148.1 - 0.00063 19.9 0.0 0.0022 18.2 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain DUF2222 PF09984.9 OWF56150.1 - 0.00093 19.1 36.3 2.5 8.0 0.6 9.0 1 1 7 8 8 8 7 Uncharacterised signal transduction histidine kinase domain (DUF2222) DUF4744 PF15918.5 OWF56150.1 - 0.16 12.9 11.9 1.3e+02 3.5 0.1 7.2 3 2 7 10 10 10 0 Domain of unknown function (DUF4744) ECSIT_C PF14784.6 OWF56150.1 - 1.7 9.0 25.8 54 4.1 0.5 8.2 1 1 6 7 7 7 0 C-terminal domain of the ECSIT protein Sigma_1s PF02454.16 OWF56150.1 - 2.2 8.3 36.5 37 4.3 0.5 9.7 1 1 10 13 13 13 0 Sigma 1s protein Fer2_2 PF01799.20 OWF56151.1 - 2.7e-06 27.3 0.0 49 4.0 0.0 5.9 6 1 0 6 6 6 4 [2Fe-2S] binding domain SCP_3 PF17844.1 OWF56151.1 - 0.03 14.1 4.4 11 5.9 0.0 4.9 6 0 0 6 6 6 0 Bacterial SCP ortholog PaRep2a PF07903.11 OWF56152.1 - 0.0041 16.9 0.0 50 3.8 0.0 4.0 1 1 4 6 6 6 5 PaRep2a protein 7tm_1 PF00001.21 OWF56153.1 - 1.3e-43 149.2 19.9 1.7e-43 148.9 19.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF56153.1 - 2.1e-11 43.7 22.8 3.2e-11 43.1 22.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF56153.1 - 6.9e-07 29.2 21.4 6.9e-07 29.2 21.4 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF56153.1 - 0.00029 20.7 18.7 0.011 15.5 18.7 2.3 1 1 0 1 1 1 1 Olfactory receptor COX7C PF02935.16 OWF56153.1 - 0.85 9.9 3.3 4.9 7.5 1.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Complex1_30kDa PF00329.19 OWF56154.1 - 0.0028 18.3 1.2 18 5.9 0.0 3.8 1 1 2 3 3 3 3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_10 PF16685.5 OWF56154.1 - 1.4 9.1 8.5 2 8.6 3.6 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 Pentapeptide_4 PF13599.6 OWF56155.1 - 8.5e-12 45.1 0.1 0.00026 21.1 0.1 4.0 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 OWF56155.1 - 3.2e-07 29.8 5.5 1.7 8.4 0.1 6.3 2 2 7 9 9 9 5 Pentapeptide repeats (8 copies) SDP_N PF12278.8 OWF56155.1 - 0.00081 19.5 1.2 79 3.4 0.0 5.3 1 1 5 7 7 7 0 Sex determination protein N terminal Sulf_coat_C PF12193.8 OWF56155.1 - 0.0014 18.6 7.1 7.6 6.7 0.1 5.7 1 1 4 6 6 6 2 Sulfolobus virus coat protein C terminal CfAFP PF05264.11 OWF56155.1 - 0.019 15.0 10.8 0.47 10.4 2.7 2.6 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Lipid_bd PF12888.7 OWF56155.1 - 0.083 13.3 6.1 8.4 6.9 0.3 4.1 1 1 3 4 4 4 0 Lipid-binding putative hydrolase IL22 PF14565.6 OWF56155.1 - 0.12 12.6 0.4 10 6.4 0.1 2.7 1 1 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Pigment_DH PF06324.11 OWF56155.1 - 5.4 7.3 13.5 33 4.9 0.0 6.9 6 1 2 8 8 8 0 Pigment-dispersing hormone (PDH) Y_phosphatase PF00102.27 OWF56156.1 - 1.5e-163 541.8 0.2 9.7e-82 274.1 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 OWF56156.1 - 1.4e-105 345.8 26.5 8.6e-15 54.9 0.1 9.3 9 0 0 9 9 9 8 Fibronectin type III domain Ig_3 PF13927.6 OWF56156.1 - 1.3e-36 125.1 7.9 4e-14 53.0 0.0 6.0 6 0 0 6 6 6 3 Immunoglobulin domain I-set PF07679.16 OWF56156.1 - 9.2e-35 118.6 0.1 1.2e-12 47.8 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF56156.1 - 2.7e-19 69.3 1.3 1.3e-07 31.9 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 OWF56156.1 - 2.2e-16 60.2 19.9 0.0019 18.7 0.1 9.3 8 2 0 8 8 8 4 Purple acid Phosphatase, N-terminal domain ig PF00047.25 OWF56156.1 - 1.4e-14 54.0 0.0 0.00045 20.3 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin domain fn3_4 PF16794.5 OWF56156.1 - 3.1e-10 39.9 0.5 3.5 7.6 0.0 8.4 9 0 0 9 9 9 2 Fibronectin-III type domain Interfer-bind PF09294.10 OWF56156.1 - 5.5e-10 39.5 0.2 0.72 10.2 0.0 7.2 7 0 0 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 OWF56156.1 - 1e-07 31.8 0.0 0.0036 17.1 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OWF56156.1 - 3.5e-06 27.2 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OWF56156.1 - 6.3e-05 23.1 0.0 0.027 14.6 0.0 2.9 2 0 0 2 2 2 1 Inositol hexakisphosphate V-set PF07686.17 OWF56156.1 - 0.00026 21.1 0.1 0.71 10.1 0.0 4.5 3 1 0 3 3 3 1 Immunoglobulin V-set domain DUF2369 PF10179.9 OWF56156.1 - 0.00047 20.5 0.9 19 5.7 0.0 4.8 3 1 1 4 4 4 0 Uncharacterised conserved protein (DUF2369) C2-set_2 PF08205.12 OWF56156.1 - 0.0011 18.9 0.5 0.47 10.6 0.0 3.6 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 OWF56156.1 - 0.0067 16.6 0.7 0.58 10.3 0.0 4.0 5 0 0 5 5 4 1 Fibronectin type III domain TMEM154 PF15102.6 OWF56156.1 - 0.0074 16.2 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF2584 PF10763.9 OWF56156.1 - 0.079 13.1 0.6 3.2 8.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2584) Adeno_E3_CR2 PF02439.15 OWF56156.1 - 1.7 8.5 9.1 3.7 7.4 3.5 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 RIO1 PF01163.22 OWF56157.1 - 1.8e-62 210.3 0.0 1.8e-62 210.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OWF56157.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF56157.1 - 0.055 12.2 0.1 0.055 12.2 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase DUF4724 PF15852.5 OWF56157.1 - 0.55 10.8 5.6 1.7 9.2 5.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4724) CCDC106 PF15794.5 OWF56157.1 - 2.1 8.0 13.8 3.6 7.2 13.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 HTH_WhiA PF02650.14 OWF56158.1 - 0.015 15.6 0.1 9 6.7 0.0 3.6 1 1 3 4 4 4 0 WhiA C-terminal HTH domain Synthase_beta PF11421.8 OWF56158.1 - 3.5 8.4 19.1 10 6.9 0.5 4.3 1 1 1 3 3 3 0 ATP synthase F1 beta subunit zf-CCHC PF00098.23 OWF56159.1 - 0.047 13.8 5.5 0.12 12.5 5.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Phage-tail_2 PF09096.10 OWF56160.1 - 0.38 10.7 3.5 5.4 6.9 0.0 3.7 1 1 1 3 3 3 0 Baseplate structural protein, domain 2 DUF1447 PF07288.11 OWF56161.1 - 0.21 11.6 19.7 60 3.8 0.1 11.0 8 7 5 14 14 14 0 Protein of unknown function (DUF1447) P53 PF00870.18 OWF56161.1 - 1.5 8.6 22.6 23 4.7 0.1 8.8 5 4 6 11 11 11 0 P53 DNA-binding domain Synaptobrevin PF00957.21 OWF56162.1 - 1e-34 118.2 3.0 1.2e-34 118.0 3.0 1.0 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.9 OWF56162.1 - 0.015 15.1 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Sigma_reg_N PF13800.6 OWF56162.1 - 0.028 14.7 1.3 0.046 14.0 1.3 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4307 PF14155.6 OWF56162.1 - 0.04 13.7 0.2 0.067 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF3619 PF12279.8 OWF56162.1 - 0.11 12.8 0.3 0.17 12.3 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) SHP PF03579.13 OWF56162.1 - 0.13 12.2 2.4 0.21 11.6 2.4 1.2 1 0 0 1 1 1 0 Small hydrophobic protein DUF4736 PF15883.5 OWF56162.1 - 0.41 10.4 5.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) FixS PF03597.15 OWF56162.1 - 0.89 9.3 6.7 1.6 8.5 6.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Galactosyl_T PF01762.21 OWF56163.1 - 2.7e-33 115.4 0.0 3.8e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase UreF PF01730.16 OWF56164.1 - 5.1e-26 91.8 0.1 6.4e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 UreF Rab5ip PF07019.12 OWF56164.1 - 0.033 14.8 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) LIM PF00412.22 OWF56165.1 - 2.6e-31 107.6 30.1 2.6e-13 50.0 7.7 3.5 3 1 0 3 3 3 3 LIM domain Pyridoxal_deC PF00282.19 OWF56166.1 - 9.9e-149 495.1 0.0 1.2e-148 494.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OWF56166.1 - 6.5e-07 28.9 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TLP-20 PF06088.11 OWF56166.1 - 0.09 12.7 0.4 0.15 12.0 0.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SepSecS PF05889.13 OWF56166.1 - 0.12 11.0 0.0 0.33 9.6 0.0 1.6 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Patched PF02460.18 OWF56167.1 - 1.5e-23 82.8 25.1 4.7e-18 64.7 3.3 3.6 3 1 1 4 4 4 2 Patched family Sterol-sensing PF12349.8 OWF56167.1 - 1.8e-12 47.4 12.8 1.8e-12 47.4 12.8 2.9 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OWF56167.1 - 1.9e-06 27.0 9.1 1.9e-06 27.0 9.1 2.3 2 0 0 2 2 2 1 MMPL family Pro_3_hydrox_C PF05373.11 OWF56168.1 - 0.016 15.3 0.0 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal PH PF00169.29 OWF56169.1 - 1.6e-22 80.0 10.7 5.8e-10 39.6 0.5 4.3 4 0 0 4 4 4 3 PH domain PH_9 PF15410.6 OWF56169.1 - 0.0076 16.6 1.0 0.15 12.5 0.1 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain REV PF00424.18 OWF56169.1 - 0.016 15.2 0.1 0.079 13.0 0.1 2.2 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) PSP94 PF05825.11 OWF56171.1 - 2.3 8.8 11.1 15 6.2 10.3 2.0 1 1 1 2 2 2 0 Beta-microseminoprotein (PSP-94) Glyco_hydro_56 PF01630.18 OWF56172.1 - 2.2e-50 171.5 0.1 3e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Hyaluronidase CCDC92 PF14916.6 OWF56173.1 - 0.039 13.7 4.5 0.095 12.5 4.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function MCU PF04678.13 OWF56173.1 - 3.3 7.8 7.1 0.57 10.3 0.6 2.7 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Glyco_hydro_56 PF01630.18 OWF56174.1 - 2.4e-46 158.3 0.1 3.9e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 OWF56174.1 - 0.035 14.4 10.8 0.046 14.0 0.3 3.2 3 0 0 3 3 3 0 EGF-like domain EGF_2 PF07974.13 OWF56174.1 - 3.7 8.0 14.3 0.83 10.1 0.8 3.2 3 0 0 3 3 3 0 EGF-like domain FtsJ PF01728.19 OWF56175.1 - 3.1e-70 235.9 0.0 4.2e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Phospholip_A2_1 PF00068.19 OWF56176.1 - 5.7e-27 94.4 12.4 8.7e-27 93.8 12.4 1.2 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 OWF56176.1 - 0.12 12.6 16.3 10 6.4 16.3 2.5 1 1 0 1 1 1 0 Phospholipase A2 fn3 PF00041.21 OWF56177.1 - 5e-14 52.4 17.1 0.0032 17.8 0.0 9.1 9 0 0 9 9 9 4 Fibronectin type III domain SAP PF02037.27 OWF56177.1 - 4.1e-10 39.2 1.4 0.00056 19.6 0.1 2.6 2 0 0 2 2 2 2 SAP domain HEAT_2 PF13646.6 OWF56177.1 - 0.00016 22.0 0.0 0.00094 19.5 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats PAN_1 PF00024.26 OWF56177.1 - 0.0015 18.5 0.0 0.0055 16.6 0.0 2.0 1 0 0 1 1 1 1 PAN domain Big_3_3 PF13750.6 OWF56177.1 - 0.033 13.8 3.7 1.5 8.5 0.1 3.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Peptidase_M23 PF01551.22 OWF56177.1 - 0.064 13.5 0.0 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 Pex14_N PF04695.13 OWF56179.1 - 3e-21 76.7 1.5 3e-21 76.7 1.5 3.5 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Cluap1 PF10234.9 OWF56179.1 - 0.017 14.5 0.8 0.017 14.5 0.8 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 LOH1CR12 PF10158.9 OWF56179.1 - 0.07 13.2 0.7 0.14 12.2 0.7 1.4 1 0 0 1 1 1 0 Tumour suppressor protein Prominin PF05478.11 OWF56179.1 - 0.17 9.8 1.8 0.26 9.2 1.8 1.2 1 0 0 1 1 1 0 Prominin DUF1522 PF07482.11 OWF56179.1 - 0.55 10.6 6.9 3.9 7.8 0.0 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1522) DUF16 PF01519.16 OWF56179.1 - 7.3 7.1 10.0 1.7 9.2 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Forkhead PF00250.18 OWF56180.1 - 3.8e-38 129.6 0.0 8.9e-38 128.4 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain 7TM_GPCR_Srsx PF10320.9 OWF56181.1 - 2.2 7.6 31.5 2.9 7.2 31.5 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 OWF56181.1 - 4.4 6.6 27.6 14 4.9 27.4 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) WD40 PF00400.32 OWF56182.1 - 4.8e-19 68.3 10.5 0.018 15.9 0.1 9.5 9 1 0 9 9 9 4 WD domain, G-beta repeat HELP PF03451.14 OWF56182.1 - 3.3e-11 42.9 0.1 7e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 HELP motif DCX PF03607.17 OWF56182.1 - 1.3e-10 41.2 0.0 9.1e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Nup160 PF11715.8 OWF56182.1 - 0.0057 15.4 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rpp20 PF12328.8 OWF56182.1 - 0.022 14.7 0.7 0.022 14.7 0.7 2.4 2 1 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Ge1_WD40 PF16529.5 OWF56182.1 - 0.028 13.4 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4680 PF15730.5 OWF56182.1 - 0.063 13.6 0.5 0.39 11.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) PDZ PF00595.24 OWF56183.1 - 9e-11 42.0 0.1 1.5e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF56183.1 - 6.8e-07 29.0 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF56183.1 - 3.4e-05 24.1 0.5 0.00012 22.3 0.1 2.1 2 1 0 2 2 2 1 PDZ domain Mucin-like PF16058.5 OWF56184.1 - 7.9e-28 96.5 18.2 0.001 19.1 0.7 6.4 1 1 5 6 6 6 6 Mucin-like Colipase-like PF15083.6 OWF56184.1 - 1.1e-25 89.5 49.4 0.0028 17.8 1.5 8.0 1 1 8 9 9 9 9 Colipase-like Mito_carr PF00153.27 OWF56185.1 - 4.6e-62 206.0 9.0 2e-21 75.7 1.4 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OWF56186.1 - 2.9e-13 48.3 11.6 1.4e-07 30.6 0.5 3.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OWF56186.1 - 1.2e-10 40.4 3.2 9.4e-05 22.1 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OWF56186.1 - 2.2e-09 37.6 1.2 2.2e-09 37.6 1.2 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OWF56186.1 - 4.3e-08 32.9 1.5 1.3e-07 31.3 1.4 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OWF56186.1 - 1.3e-06 27.6 6.4 0.00062 19.1 0.6 3.1 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 OWF56186.1 - 0.00014 22.2 0.0 0.00014 22.2 0.0 2.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF56186.1 - 0.7 9.9 3.9 5.5 7.0 1.0 2.6 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OWF56186.1 - 2.4 8.1 5.6 0.47 10.4 0.3 2.2 2 1 1 3 3 3 0 Caleosin related protein DCAF17 PF15802.5 OWF56187.1 - 5.9e-131 437.5 0.0 7.5e-131 437.1 0.0 1.1 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 Ras PF00071.22 OWF56187.1 - 2.8e-15 56.3 0.1 4.5e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56187.1 - 2.5e-12 47.1 0.1 4.7e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OWF56187.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Methyltr_RsmB-F PF01189.17 OWF56188.1 - 6.4e-30 104.3 0.2 6.9e-29 100.9 0.0 2.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OWF56188.1 - 0.0047 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 OWF56188.1 - 0.06 14.0 0.6 9.8 7.0 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Glyco_transf_8 PF01501.20 OWF56189.1 - 1.9e-51 175.1 0.2 2.6e-51 174.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 OWF56189.1 - 3.9e-06 26.5 0.3 6.3e-06 25.8 0.3 1.4 1 1 0 1 1 1 1 Glucosyltransferase 24 CPSase_L_D2 PF02786.17 OWF56190.1 - 3.1e-112 373.2 0.5 3e-82 275.2 0.1 2.6 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 OWF56190.1 - 2e-44 151.2 0.2 3.9e-44 150.3 0.2 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 OWF56190.1 - 8.4e-38 129.5 1.2 2.6e-37 127.9 1.2 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OWF56190.1 - 2e-32 112.5 0.0 5.1e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 OWF56190.1 - 5.7e-19 68.5 0.4 1.7e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus GATase PF00117.28 OWF56190.1 - 3.6e-17 62.8 0.0 1.3e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I MGS PF02142.22 OWF56190.1 - 3.8e-17 62.3 0.0 1.5e-16 60.4 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 OWF56190.1 - 5.1e-17 62.0 0.4 2.4e-10 40.3 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OWF56190.1 - 1.2e-10 41.2 0.1 0.00019 21.2 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_1 PF01979.20 OWF56190.1 - 4.6e-10 39.3 0.0 1.1e-07 31.5 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family ATP-grasp_3 PF02655.14 OWF56190.1 - 1.1e-08 35.3 0.3 0.00022 21.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain DHOase PF12890.7 OWF56190.1 - 0.0017 18.2 0.0 0.0065 16.4 0.0 2.0 2 0 0 2 2 2 1 Dihydro-orotase-like GARS_A PF01071.19 OWF56190.1 - 0.0076 16.0 0.2 0.033 13.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_sm_chain PF00988.22 OWF56191.1 - 2.5e-50 169.6 0.0 3.7e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OWF56191.1 - 3.2e-22 79.2 0.1 4.4e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OWF56191.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 DJ-1_PfpI PF01965.24 OWF56191.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Pox_A3L PF05288.11 OWF56191.1 - 0.16 12.0 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A3L Protein Tmem26 PF09772.9 OWF56192.1 - 2.2e-95 319.3 8.1 2.6e-95 319.1 8.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 DALR_2 PF09190.11 OWF56192.1 - 0.046 14.2 0.1 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 DALR domain DUF2818 PF10993.8 OWF56192.1 - 0.35 11.5 5.2 2.1 9.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) Pex14_N PF04695.13 OWF56193.1 - 0.074 13.7 2.1 1.4 9.6 0.3 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gp_dh_C PF02800.20 OWF56194.1 - 6.2e-70 233.8 0.0 9.8e-70 233.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OWF56194.1 - 9.1e-36 122.2 0.0 1.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OWF56194.1 - 0.027 13.8 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 OWF56195.1 - 1.5e-37 126.9 3.9 8.3e-07 29.6 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat CSTF1_dimer PF16699.5 OWF56195.1 - 1.2e-27 95.4 0.1 2e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 OWF56195.1 - 5.9e-16 58.5 0.0 0.015 15.6 0.0 4.9 2 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF56195.1 - 9e-05 22.4 0.1 0.0004 20.3 0.1 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OWF56195.1 - 0.011 14.1 0.1 0.071 11.4 0.0 2.2 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz BBS2_Mid PF14783.6 OWF56195.1 - 0.012 15.6 0.0 11 6.0 0.0 3.7 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 OWF56195.1 - 0.014 14.0 0.0 0.035 12.6 0.0 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 OWF56195.1 - 0.09 12.1 0.1 20 4.4 0.0 3.0 4 0 0 4 4 4 0 WD40-like domain Cornifin PF02389.15 OWF56196.1 - 0.13 12.4 12.9 0.21 11.8 12.7 1.5 1 1 0 1 1 1 0 Cornifin (SPRR) family Fzo_mitofusin PF04799.13 OWF56197.1 - 4e-66 221.5 1.5 4e-66 221.5 1.5 3.2 2 1 1 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.23 OWF56197.1 - 1.5e-22 80.5 0.1 6.3e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OWF56197.1 - 1.8e-06 28.0 0.0 1.4e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase eIF-4B PF06273.11 OWF56197.1 - 0.0086 15.2 1.5 0.014 14.5 1.5 1.2 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B AIG1 PF04548.16 OWF56197.1 - 0.02 14.2 0.7 0.18 11.1 0.2 2.5 1 1 1 2 2 2 0 AIG1 family GrpE PF01025.19 OWF56197.1 - 0.14 11.8 9.5 1.2 8.8 0.1 3.4 3 1 0 3 3 3 0 GrpE DUF1664 PF07889.12 OWF56197.1 - 0.23 11.5 8.1 2.3 8.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 OWF56197.1 - 0.33 10.5 5.4 0.22 11.1 0.3 2.5 2 0 0 2 2 2 0 PspA/IM30 family Apolipoprotein PF01442.18 OWF56197.1 - 0.41 10.5 8.7 2.7 7.8 2.7 2.9 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain BLYB PF05289.11 OWF56197.1 - 2.3 8.4 5.8 1 9.6 1.2 2.7 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein PhaP_Bmeg PF09602.10 OWF56197.1 - 2.7 7.9 9.6 0.55 10.1 0.8 3.5 3 1 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phage_HK97_TLTM PF06120.11 OWF56197.1 - 4.9 6.3 7.2 10 5.2 0.5 3.4 4 0 0 4 4 4 0 Tail length tape measure protein Ank_2 PF12796.7 OWF56198.1 - 2.5e-30 104.9 5.0 1.2e-10 41.8 0.0 4.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF56198.1 - 1.5e-21 76.4 1.0 0.001 19.6 0.0 6.6 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OWF56198.1 - 2.6e-19 68.7 5.4 0.00031 21.1 0.0 7.9 9 0 0 9 9 8 4 Ankyrin repeat Ank_5 PF13857.6 OWF56198.1 - 2.8e-19 68.9 1.3 5.6e-06 26.5 0.0 6.4 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56198.1 - 1.2e-17 62.1 2.1 0.9 10.3 0.0 8.9 9 0 0 9 9 8 3 Ankyrin repeat AAA_23 PF13476.6 OWF56198.1 - 0.0017 18.9 0.1 0.005 17.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OWF56198.1 - 0.0047 17.2 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OWF56198.1 - 0.0073 16.9 0.0 0.052 14.1 0.0 2.5 2 1 1 3 3 3 1 AAA domain DAP3 PF10236.9 OWF56198.1 - 0.009 15.2 0.0 0.025 13.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.15 OWF56198.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 OWF56198.1 - 0.015 15.7 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OWF56198.1 - 0.029 14.1 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OWF56198.1 - 0.034 13.9 0.0 0.098 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OWF56198.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OWF56198.1 - 0.084 13.3 0.0 1 9.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NTPase_1 PF03266.15 OWF56198.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 OWF56198.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 OWF56198.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OWF56198.1 - 0.14 11.5 0.4 0.82 9.0 0.0 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family TMEM154 PF15102.6 OWF56199.1 - 7.5e-05 22.7 0.3 7.5e-05 22.7 0.3 1.9 2 0 0 2 2 2 1 TMEM154 protein family Prominin PF05478.11 OWF56199.1 - 0.00074 17.6 0.6 0.0011 17.1 0.6 1.1 1 0 0 1 1 1 1 Prominin EphA2_TM PF14575.6 OWF56199.1 - 0.086 13.7 0.0 0.28 12.1 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ABC2_membrane_3 PF12698.7 OWF56199.1 - 0.13 11.4 0.8 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4448 PF14610.6 OWF56199.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Podoplanin PF05808.11 OWF56199.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Podoplanin EVI2A PF05399.11 OWF56199.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.5 2 1 1 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) MLANA PF14991.6 OWF56199.1 - 0.22 11.8 4.4 0.92 9.8 4.4 2.0 1 1 0 1 1 1 0 Protein melan-A zf-B_box PF00643.24 OWF56200.1 - 1.6e-10 40.9 19.3 1.7e-07 31.2 4.4 3.3 2 0 0 2 2 2 2 B-box zinc finger zf-C3HC4_3 PF13920.6 OWF56200.1 - 2.4e-07 30.5 9.4 2.4e-07 30.5 9.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) fn3 PF00041.21 OWF56200.1 - 1e-06 29.0 0.1 0.00018 21.8 0.0 2.7 2 0 0 2 2 2 1 Fibronectin type III domain zf-RING_UBOX PF13445.6 OWF56200.1 - 1.3e-06 28.3 7.0 1.3e-06 28.3 7.0 3.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OWF56200.1 - 4.1e-05 23.8 10.4 4.1e-05 23.8 10.4 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 OWF56200.1 - 0.0015 18.4 9.3 0.0015 18.4 9.3 3.5 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF56200.1 - 0.0018 18.1 10.1 0.0018 18.1 10.1 3.7 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OWF56200.1 - 0.0025 17.9 10.8 0.0025 17.9 10.8 5.4 5 1 1 6 6 6 1 zinc finger of C3HC4-type, RING CEBP_ZZ PF16366.5 OWF56200.1 - 0.0031 17.7 1.9 0.0031 17.7 1.9 2.9 3 0 0 3 3 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain U-box PF04564.15 OWF56200.1 - 0.0068 16.6 0.0 0.026 14.7 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 OWF56200.1 - 0.0081 16.1 7.6 0.0081 16.1 7.6 3.6 3 0 0 3 3 3 1 zinc-RING finger domain Fibin PF15819.5 OWF56200.1 - 0.064 13.0 3.8 4.8 6.9 0.5 2.3 1 1 1 2 2 2 0 Fin bud initiation factor homologue KH_10 PF17905.1 OWF56200.1 - 0.085 13.3 0.2 0.26 11.7 0.2 1.8 1 0 0 1 1 1 0 GLD-3 KH domain 5 Uso1_p115_C PF04871.13 OWF56200.1 - 0.1 13.0 5.4 0.24 11.8 5.4 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-Nse PF11789.8 OWF56200.1 - 0.25 11.2 7.1 0.63 9.9 7.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3450 PF11932.8 OWF56200.1 - 0.26 10.6 6.3 0.4 10.0 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 OWF56200.1 - 0.37 10.0 2.3 0.57 9.4 2.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein 7TMR-HDED PF07697.11 OWF56200.1 - 0.37 10.9 3.6 0.72 9.9 3.6 1.4 1 0 0 1 1 1 0 7TM-HD extracellular Cu2_monooxygen PF01082.20 OWF56201.1 - 4.2e-29 101.4 0.3 9.5e-29 100.3 0.3 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 OWF56201.1 - 2.4e-17 62.9 0.1 3.9e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Myb_DNA-binding PF00249.31 OWF56202.1 - 1.3e-22 79.7 2.0 2.3e-10 40.5 0.1 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OWF56202.1 - 5.5e-14 52.2 8.8 1.9e-09 37.6 0.1 4.5 2 1 3 5 5 5 3 Myb-like DNA-binding domain Macoilin PF09726.9 OWF56202.1 - 0.12 10.9 20.4 0.18 10.3 20.4 1.3 1 0 0 1 1 1 0 Macoilin family MULE PF10551.9 OWF56203.1 - 2.9e-06 27.6 0.0 7.7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain ASH PF15780.5 OWF56204.1 - 9.9e-19 67.4 10.5 9.5e-05 22.5 0.0 9.2 9 0 0 9 9 9 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OWF56204.1 - 3.3e-09 36.8 1.4 0.007 16.5 0.0 5.7 5 1 0 5 5 5 2 Flagellar-associated PapD-like DUF1573 PF07610.11 OWF56204.1 - 8.9e-09 35.3 1.1 4.4 7.4 0.0 6.5 6 0 0 6 6 6 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OWF56204.1 - 2e-06 27.9 2.1 0.074 13.3 0.0 6.6 8 0 0 8 8 8 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 OWF56204.1 - 1.4e-05 24.9 6.0 0.48 10.3 0.1 6.5 7 1 0 7 7 7 2 MSP (Major sperm protein) domain fn3_5 PF06280.12 OWF56204.1 - 0.0011 19.6 12.5 0.65 10.7 0.0 6.0 6 0 0 6 6 6 2 Fn3-like domain zf-C2H2_4 PF13894.6 OWF56205.1 - 3.3e-19 67.9 138.4 0.00088 19.9 1.0 16.8 16 0 0 16 16 16 11 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF56205.1 - 9.1e-15 54.2 140.8 0.0015 18.9 2.3 16.7 16 0 0 16 16 15 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF56205.1 - 8.5e-08 32.3 119.5 1.4e-06 28.4 1.1 16.0 17 0 0 17 17 17 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 OWF56205.1 - 9.2e-05 22.1 0.5 9.2e-05 22.1 0.5 10.1 13 1 0 13 13 11 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OWF56205.1 - 0.0019 18.2 0.2 0.0019 18.2 0.2 11.8 12 0 0 12 12 12 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF56205.1 - 0.015 15.6 75.1 0.07 13.4 0.0 12.7 13 1 0 13 13 12 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF56205.1 - 0.033 14.6 0.3 0.033 14.6 0.3 13.4 16 0 0 16 16 16 0 Zinc-finger of C2H2 type DUF3222 PF11519.8 OWF56205.1 - 0.079 13.2 0.0 0.44 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) BolA PF01722.18 OWF56205.1 - 0.12 12.6 4.8 17 5.8 0.0 4.0 3 1 1 4 4 4 0 BolA-like protein zf_C2H2_13 PF18508.1 OWF56205.1 - 3.5 7.3 22.0 0.14 11.8 2.6 5.7 3 2 2 5 5 5 0 Zinc finger domain AT_hook PF02178.19 OWF56205.1 - 4.1 7.6 9.4 14 5.9 9.4 2.0 1 0 0 1 1 1 0 AT hook motif PAN_1 PF00024.26 OWF56206.1 - 0.00017 21.5 0.3 0.00021 21.2 0.3 1.2 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF56206.1 - 0.0087 15.9 0.9 0.017 15.0 0.9 1.6 1 1 0 1 1 1 1 PAN domain DUF4097 PF13349.6 OWF56207.1 - 8.9e-05 21.9 2.9 0.00029 20.2 2.9 1.8 1 1 0 1 1 1 1 Putative adhesin AsmA_2 PF13502.6 OWF56207.1 - 0.00023 20.8 11.3 0.0043 16.6 7.5 2.6 1 1 1 2 2 2 2 AsmA-like C-terminal region MORN PF02493.20 OWF56207.1 - 0.00027 20.6 11.5 13 5.9 0.4 5.9 6 0 0 6 6 6 2 MORN repeat T2SSN PF01203.19 OWF56207.1 - 0.0017 18.6 8.1 0.027 14.7 2.5 2.1 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein N DUF3971 PF13116.6 OWF56207.1 - 0.015 14.8 20.0 0.45 10.0 8.8 2.4 1 1 1 2 2 2 0 Protein of unknown function HemN_C PF06969.16 OWF56207.1 - 0.18 11.9 5.1 5.8 7.0 0.1 2.9 3 0 0 3 3 3 0 HemN C-terminal domain DUF2982 PF11201.8 OWF56207.1 - 0.25 10.9 4.9 3.7 7.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2982) Scm3 PF10384.9 OWF56207.1 - 4.1 7.2 9.3 27 4.6 0.0 4.8 4 1 2 6 6 6 0 Centromere protein Scm3 DUF2724 PF10893.8 OWF56207.1 - 6.1 6.8 16.1 40 4.1 0.2 5.6 1 1 6 7 7 7 0 Protein of unknown function (DUF2724) DUF4097 PF13349.6 OWF56208.1 - 7.7e-23 81.1 28.0 4.5e-11 42.6 4.5 3.9 1 1 3 4 4 4 4 Putative adhesin AsmA_2 PF13502.6 OWF56208.1 - 4.7e-11 42.6 30.3 0.0016 18.1 20.4 4.2 1 1 1 2 2 2 2 AsmA-like C-terminal region DctA-YdbH PF11739.8 OWF56208.1 - 2.6e-08 33.8 30.3 0.044 13.5 2.8 5.1 1 1 4 5 5 5 5 Dicarboxylate transport T2SSN PF01203.19 OWF56208.1 - 4.1e-08 33.7 24.6 0.0027 18.0 5.8 3.3 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein N DUF3971 PF13116.6 OWF56208.1 - 7.9e-07 28.9 50.8 0.029 13.9 6.9 5.1 1 1 4 5 5 5 3 Protein of unknown function SmpB PF01668.18 OWF56208.1 - 2.5e-06 27.4 8.2 0.34 10.7 0.2 5.7 1 1 6 7 7 7 2 SmpB protein DUF1958 PF09211.10 OWF56208.1 - 9.8e-05 22.6 7.1 36 4.8 0.1 7.2 1 1 6 7 7 7 0 Domain of unknown function (DUF1958) DUF1794 PF08768.11 OWF56208.1 - 0.00071 19.5 2.1 4.2 7.3 0.2 4.3 1 1 1 2 2 2 1 Domain of unknown function (DUF1794) DUF3540 PF12059.8 OWF56208.1 - 0.0011 18.8 5.3 3 7.6 0.7 3.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3540) Toast_rack_N PF17115.5 OWF56208.1 - 0.0017 18.6 21.6 3.4 8.0 3.6 6.5 1 1 6 7 7 7 2 N-terminal domain of toast_rack, DUF2154 Cu_amine_oxidN1 PF07833.11 OWF56208.1 - 0.041 14.4 0.8 51 4.5 0.0 4.3 1 1 1 2 2 2 0 Copper amine oxidase N-terminal domain Scm3 PF10384.9 OWF56208.1 - 0.058 13.1 23.6 51 3.7 0.1 10.1 3 3 6 11 11 11 0 Centromere protein Scm3 DUF5012 PF16404.5 OWF56208.1 - 0.1 12.7 6.2 22 5.2 0.0 4.0 1 1 2 4 4 4 0 Domain of unknown function (DUF5012) MORN PF02493.20 OWF56208.1 - 0.14 12.1 13.4 35 4.6 0.4 7.5 8 1 0 8 8 6 0 MORN repeat Spc7 PF08317.11 OWF56208.1 - 2.1 7.1 4.3 5.3 5.8 2.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein IL1_propep PF02394.16 OWF56208.1 - 3.1 8.8 8.9 40 5.2 0.2 4.3 1 1 3 4 4 4 0 Interleukin-1 propeptide AsmA PF05170.14 OWF56208.1 - 3.3 6.4 52.6 7.9 5.1 16.7 4.3 1 1 3 4 4 4 0 AsmA family DUF3872 PF12988.7 OWF56208.1 - 4 7.3 20.3 18 5.1 1.0 5.7 1 1 5 6 6 6 0 Domain of unknown function, B. Theta Gene description (DUF3872) Pox_G9-A16 PF03003.16 OWF56208.1 - 6.6 6.5 17.9 48 3.7 1.2 5.5 1 1 3 4 4 4 0 Pox virus entry-fusion-complex G9/A16 FAD-oxidase_C PF02913.19 OWF56209.1 - 1e-54 185.8 0.0 1.3e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OWF56209.1 - 8.5e-35 119.5 0.4 1.4e-34 118.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain SRCR PF00530.18 OWF56210.1 - 1.4e-32 112.2 1.1 3.2e-32 111.0 1.1 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 OWF56210.1 - 9.4e-18 64.2 24.9 4.9e-10 39.5 6.9 3.6 5 0 0 5 5 5 2 Low-density lipoprotein receptor domain class A SRCR_2 PF15494.6 OWF56210.1 - 2.4e-06 28.0 1.1 4.7e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Ig_3 PF13927.6 OWF56211.1 - 0 1181.9 304.3 8.3e-13 48.7 3.0 34.2 34 0 0 34 34 34 34 Immunoglobulin domain I-set PF07679.16 OWF56211.1 - 0 991.6 148.7 6.8e-11 42.1 0.4 34.4 33 1 1 34 34 34 34 Immunoglobulin I-set domain ig PF00047.25 OWF56211.1 - 1.6e-219 710.8 250.1 1.9e-09 37.6 1.2 34.4 34 0 0 34 34 34 33 Immunoglobulin domain Ig_2 PF13895.6 OWF56211.1 - 1.9e-186 604.9 275.8 3.1e-08 33.8 1.0 34.3 33 1 1 34 34 34 34 Immunoglobulin domain V-set PF07686.17 OWF56211.1 - 1.9e-167 546.1 232.0 6.6e-08 32.7 1.1 47.3 34 27 0 34 34 34 32 Immunoglobulin V-set domain Ig_5 PF16681.5 OWF56211.1 - 1.4e-24 86.3 37.4 1.3 9.5 0.1 27.6 31 0 0 31 31 30 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 OWF56211.1 - 1.9e-20 72.7 21.3 5.5 7.1 0.0 24.7 32 0 0 32 32 32 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 OWF56211.1 - 1.7e-19 69.1 26.1 0.38 10.4 0.0 22.5 27 0 0 27 27 27 3 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF56211.1 - 2.7e-15 56.2 98.6 0.32 11.0 0.1 30.1 33 0 0 33 33 33 6 C17orf99 Ig domain Receptor_2B4 PF11465.8 OWF56211.1 - 1.1e-13 51.3 86.5 1.4 9.2 0.6 25.4 19 7 10 30 30 29 7 Natural killer cell receptor 2B4 Ig_4 PF16680.5 OWF56211.1 - 1.3e-13 51.0 39.1 0.11 12.8 0.1 23.6 32 1 0 32 32 27 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 OWF56211.1 - 5.3e-09 36.1 23.0 2 8.7 0.1 17.5 17 0 0 17 17 17 1 Immunoglobulin C2-set domain DUF3931 PF13082.6 OWF56211.1 - 2.6e-05 24.3 18.8 32 4.8 0.1 11.1 12 0 0 12 12 12 0 Protein of unknown function (DUF3931) C1-set PF07654.15 OWF56211.1 - 0.005 17.2 121.7 2.3 8.7 0.6 25.0 30 0 0 30 30 29 7 Immunoglobulin C1-set domain TMIE PF16038.5 OWF56211.1 - 0.29 11.0 4.9 0.58 10.0 4.9 1.4 1 0 0 1 1 1 0 TMIE protein DED PF01335.21 OWF56212.1 - 3.1e-14 53.0 1.7 3.8e-14 52.8 0.6 1.7 2 0 0 2 2 2 1 Death effector domain Death PF00531.22 OWF56212.1 - 4.1e-09 36.5 0.1 7.9e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Death domain Alpha-2-MRAP_C PF06401.11 OWF56213.1 - 1.8e-44 152.3 38.9 3.4e-44 151.3 32.8 2.2 2 0 0 2 2 2 2 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 OWF56213.1 - 1.1e-33 115.7 33.6 3.4e-31 107.6 1.7 3.3 1 1 2 3 3 3 2 Alpha-2-macroglobulin RAP, N-terminal domain T3SS_needle_E PF08988.10 OWF56213.1 - 0.41 10.8 2.2 2.4 8.3 0.1 3.1 3 1 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Peptidase_C37 PF05416.12 OWF56213.1 - 0.58 8.6 13.2 0.58 8.6 7.0 2.2 2 1 0 2 2 2 0 Southampton virus-type processing peptidase Phe_tRNA-synt_N PF02912.18 OWF56213.1 - 1.5 8.8 7.5 3.1 7.8 0.5 3.2 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1664 PF07889.12 OWF56213.1 - 1.8 8.6 5.0 1.2 9.2 0.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3194 PF11419.8 OWF56214.1 - 0.49 10.8 8.1 16 5.9 0.3 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF3194) HCR PF07111.12 OWF56215.1 - 0.0038 15.4 13.3 0.44 8.6 0.2 5.0 1 1 6 7 7 7 5 Alpha helical coiled-coil rod protein (HCR) MCM_lid PF17855.1 OWF56215.1 - 2.9 8.4 21.1 1.1e+02 3.3 0.1 8.8 1 1 4 8 8 8 0 MCM AAA-lid domain PKD_channel PF08016.12 OWF56216.1 - 3e-93 312.8 11.6 3e-93 312.8 11.6 2.1 1 1 1 2 2 2 1 Polycystin cation channel REJ PF02010.15 OWF56216.1 - 3.1e-49 168.0 10.4 1.3e-34 119.9 0.1 2.8 2 1 1 3 3 3 2 REJ domain PLAT PF01477.23 OWF56216.1 - 3.6e-18 66.2 0.4 1.6e-17 64.1 0.3 2.3 1 1 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 OWF56216.1 - 2.3e-11 43.4 30.4 2.3e-11 43.4 30.4 3.0 3 0 0 3 3 3 2 Ion transport protein GPS PF01825.21 OWF56216.1 - 5.2e-08 33.3 1.7 5.2e-08 33.3 1.7 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif EGF_CA PF07645.15 OWF56218.1 - 4e-143 465.4 420.0 4.3e-10 39.6 11.1 23.9 23 1 1 24 24 24 22 Calcium-binding EGF domain EGF PF00008.27 OWF56218.1 - 2.3e-100 328.3 409.0 9.3e-09 35.4 12.2 25.5 25 1 0 25 25 25 22 EGF-like domain hEGF PF12661.7 OWF56218.1 - 1.2e-58 193.8 367.5 7.1e-06 26.5 3.7 25.9 25 0 0 25 25 25 20 Human growth factor-like EGF EGF_3 PF12947.7 OWF56218.1 - 5.2e-25 87.3 404.7 0.00093 19.3 7.4 24.8 19 4 4 23 23 23 16 EGF domain EGF_2 PF07974.13 OWF56218.1 - 1.9e-18 66.5 492.6 0.002 18.4 15.7 25.3 24 2 1 25 25 25 17 EGF-like domain FXa_inhibition PF14670.6 OWF56218.1 - 8.1e-11 42.0 358.3 0.35 11.2 12.6 23.5 2 2 20 22 22 22 10 Coagulation Factor Xa inhibitory site DSL PF01414.19 OWF56218.1 - 1.6e-06 28.3 2.0 1.6e-06 28.3 2.0 19.9 13 5 7 20 20 20 2 Delta serrate ligand cEGF PF12662.7 OWF56218.1 - 0.00032 20.6 228.5 0.024 14.6 2.3 25.6 23 2 0 23 23 23 14 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 OWF56218.1 - 0.0013 18.7 9.5 0.0013 18.7 9.5 21.7 20 1 1 21 21 21 6 MSP1 EGF domain 1 NPCBM_assoc PF10633.9 OWF56218.1 - 0.048 13.9 0.0 14 6.0 0.0 3.9 3 1 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase EGF_CA PF07645.15 OWF56220.1 - 2.3e-19 69.3 28.7 6.4e-09 35.9 8.2 3.3 3 0 0 3 3 3 3 Calcium-binding EGF domain hEGF PF12661.7 OWF56220.1 - 1.1e-10 41.7 23.2 3.5e-06 27.4 3.2 4.1 4 0 0 4 4 4 2 Human growth factor-like EGF EGF PF00008.27 OWF56220.1 - 2.2e-10 40.6 30.3 6.2e-06 26.4 2.7 4.1 6 0 0 6 6 6 3 EGF-like domain EGF_3 PF12947.7 OWF56220.1 - 3.3e-08 33.6 27.0 0.00039 20.6 5.2 4.2 3 2 0 3 3 3 2 EGF domain FXa_inhibition PF14670.6 OWF56220.1 - 1.1e-07 32.0 20.4 0.0023 18.2 7.3 2.9 1 1 1 2 2 2 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 OWF56220.1 - 6.5e-06 26.0 18.0 0.0017 18.3 2.4 4.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 OWF56220.1 - 0.0004 20.4 17.1 0.052 13.6 3.9 3.1 2 0 0 2 2 2 2 MSP1 EGF domain 1 EGF_2 PF07974.13 OWF56220.1 - 0.029 14.7 6.7 0.029 14.7 6.7 3.7 4 1 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 OWF56220.1 - 0.047 13.8 26.7 0.18 11.9 10.4 2.8 2 1 0 2 2 2 0 Laminin EGF domain Plasmod_Pvs28 PF06247.11 OWF56220.1 - 0.32 11.3 21.7 1.6 9.1 9.6 2.6 2 1 0 2 2 2 0 Pvs28 EGF domain DUF4906 PF16249.5 OWF56222.1 - 1.2 8.9 5.2 0.68 9.8 3.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4906) DUF4906 PF16249.5 OWF56223.1 - 1.2 8.9 5.2 0.68 9.8 3.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4906) DUF4906 PF16249.5 OWF56224.1 - 3.4 7.5 7.5 0.48 10.2 2.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4906) EGF_CA PF07645.15 OWF56225.1 - 2.1e-34 117.4 62.2 1e-09 38.5 9.7 4.4 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.27 OWF56225.1 - 7e-22 77.4 51.6 1.2e-06 28.7 7.0 4.3 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 OWF56225.1 - 1.5e-18 66.7 53.3 3.9e-05 24.1 4.4 5.3 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_3 PF12947.7 OWF56225.1 - 1.2e-14 54.1 54.2 5.1e-05 23.4 5.4 4.9 3 2 1 4 4 4 4 EGF domain FXa_inhibition PF14670.6 OWF56225.1 - 2.8e-09 37.1 46.4 0.013 15.8 5.4 4.9 1 1 3 4 4 4 4 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 OWF56225.1 - 1.5e-06 28.4 69.0 0.034 14.5 10.8 4.3 4 0 0 4 4 4 4 EGF-like domain cEGF PF12662.7 OWF56225.1 - 1.4e-05 24.9 27.4 0.024 14.6 2.1 4.9 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 OWF56225.1 - 0.00011 22.1 55.2 0.092 12.8 9.8 4.5 4 0 0 4 4 4 3 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 OWF56225.1 - 0.00044 20.5 48.1 0.082 13.2 11.2 5.1 5 0 0 5 5 5 4 Pvs28 EGF domain Orthoreo_P10 PF07204.11 OWF56225.1 - 0.0016 18.4 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Trp_oprn_chp PF09534.10 OWF56225.1 - 0.0022 17.8 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LRR19-TM PF15176.6 OWF56225.1 - 0.072 13.1 1.6 0.085 12.9 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain EGF_CA PF07645.15 OWF56226.1 - 8.8e-244 787.6 620.1 7.2e-09 35.7 8.2 37.1 33 4 4 37 37 37 35 Calcium-binding EGF domain EGF PF00008.27 OWF56226.1 - 9.5e-165 534.1 591.9 2.9e-07 30.7 10.1 37.8 37 0 0 37 37 37 36 EGF-like domain hEGF PF12661.7 OWF56226.1 - 9.9e-108 349.6 573.5 8.9e-07 29.3 9.8 39.3 38 0 0 38 38 38 36 Human growth factor-like EGF EGF_2 PF07974.13 OWF56226.1 - 7.9e-94 307.6 715.0 0.00022 21.5 13.0 37.8 37 0 0 37 37 37 36 EGF-like domain EGF_3 PF12947.7 OWF56226.1 - 1.9e-12 47.2 559.1 0.033 14.4 8.9 38.1 33 5 3 36 36 36 29 EGF domain FXa_inhibition PF14670.6 OWF56226.1 - 4.1e-10 39.8 544.7 0.066 13.5 5.4 37.9 10 8 27 37 37 37 15 Coagulation Factor Xa inhibitory site DSL PF01414.19 OWF56226.1 - 9.8e-07 29.0 1.2 9.8e-07 29.0 1.2 26.8 14 7 14 28 28 28 1 Delta serrate ligand zf-RING_2 PF13639.6 OWF56227.1 - 7.4e-05 23.0 9.2 0.00014 22.2 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OWF56227.1 - 0.00014 21.6 8.2 0.0003 20.6 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF56227.1 - 0.00029 20.6 9.9 0.00055 19.8 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OWF56227.1 - 0.00066 19.6 7.1 0.0015 18.5 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OWF56227.1 - 0.0025 17.7 6.3 0.0049 16.7 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OWF56227.1 - 0.1 12.7 10.2 0.2 11.8 10.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF148 PF02520.17 OWF56227.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 zf-WRNIP1_ubi PF18279.1 OWF56227.1 - 0.73 10.6 2.8 2.5 8.9 0.2 2.4 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain SOG2 PF10428.9 OWF56227.1 - 3.6 6.7 17.2 5.4 6.1 17.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Uds1 PF15456.6 OWF56227.1 - 3.7 7.7 7.8 0.79 9.9 3.7 1.9 1 1 1 2 2 2 0 Up-regulated During Septation Hamartin PF04388.12 OWF56227.1 - 4 6.0 9.0 5 5.7 9.0 1.1 1 0 0 1 1 1 0 Hamartin protein Rax2 PF12768.7 OWF56228.1 - 0.0044 16.5 0.4 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Mustang PF15682.5 OWF56228.1 - 0.0058 16.7 0.4 0.35 11.0 0.0 3.3 3 0 0 3 3 3 1 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Shisa PF13908.6 OWF56228.1 - 0.021 15.1 1.3 0.039 14.2 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Pilin_N PF07790.11 OWF56228.1 - 0.032 15.2 0.1 0.22 12.4 0.1 2.3 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal EphA2_TM PF14575.6 OWF56228.1 - 0.049 14.5 0.0 0.049 14.5 0.0 3.9 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 OWF56228.1 - 0.053 14.0 0.9 0.15 12.5 0.0 2.3 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT ECSCR PF15820.5 OWF56228.1 - 0.13 12.1 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator FAM176 PF14851.6 OWF56228.1 - 0.13 11.9 0.0 0.13 11.9 0.0 4.2 2 1 1 3 3 3 0 FAM176 family Lig_chan-Glu_bd PF10613.9 OWF56229.1 - 2e-27 95.7 0.0 3.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 OWF56229.1 - 3.3e-27 95.2 0.1 4.9e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OWF56229.1 - 1.8e-20 73.4 0.0 3.6e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 OWF56229.1 - 0.0091 15.9 0.9 0.0091 15.9 0.9 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 OWF56229.1 - 0.058 12.6 0.7 0.28 10.4 0.9 2.0 2 0 0 2 2 2 0 Ion transport protein GRAM PF02893.20 OWF56230.1 - 6.9e-13 48.5 0.0 1.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Pex24p PF06398.11 OWF56230.1 - 1.1e-05 24.6 4.5 2.7e-05 23.4 4.4 1.6 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin DUF639 PF04842.12 OWF56230.1 - 1.2e-05 24.8 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) PRT_C PF08372.10 OWF56230.1 - 1.5e-05 24.8 3.9 0.00051 19.8 0.0 2.3 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.8 OWF56230.1 - 0.00018 20.1 0.1 0.037 12.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) Vps36_ESCRT-II PF11605.8 OWF56230.1 - 0.025 14.8 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 GAS PF13851.6 OWF56230.1 - 0.04 13.3 5.1 0.022 14.1 2.3 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tn7_TnsC_Int PF11426.8 OWF56233.1 - 5.8e-08 32.8 16.9 7.1 6.9 0.2 11.3 12 0 0 12 12 12 2 Tn7 transposition regulator TnsC PapD_N PF00345.20 OWF56233.1 - 1.8e-06 27.9 37.7 0.67 9.9 0.0 11.1 7 3 2 10 10 10 4 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF3410 PF11890.8 OWF56233.1 - 0.00059 19.6 12.5 1.6 8.5 0.0 6.2 7 3 2 9 9 9 2 Domain of unknown function (DUF3410) CBM60 PF16841.5 OWF56233.1 - 0.0029 18.0 25.2 35 4.9 0.2 9.8 6 2 4 10 10 10 0 Ca-dependent carbohydrate-binding module xylan-binding DUF3718 PF12514.8 OWF56233.1 - 0.11 12.6 19.4 14 6.0 0.0 10.4 10 5 4 15 15 15 0 Protein of unknown function (DUF3718) Pox_A28 PF04584.14 OWF56233.1 - 0.61 10.3 19.7 49 4.1 0.2 7.2 5 1 3 9 9 9 0 Poxvirus A28 family DUF4466 PF14725.6 OWF56233.1 - 6.8 6.1 26.4 20 4.6 0.9 6.9 2 2 4 8 8 8 0 Domain of unknown function (DUF4466) DAN PF03045.15 OWF56234.1 - 3.8e-05 23.7 10.4 6.1e-05 23.0 10.4 1.3 1 0 0 1 1 1 1 DAN domain CAP PF00188.26 OWF56235.1 - 3.4e-09 37.6 0.3 7.1e-09 36.6 0.3 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Exo_endo_phos_2 PF14529.6 OWF56236.1 - 1.8e-10 40.7 2.1 3.3e-10 39.8 2.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OWF56236.1 - 0.00024 20.7 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ras PF00071.22 OWF56237.1 - 1.4e-58 197.1 2.1 1.6e-58 196.9 2.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56237.1 - 3.3e-34 117.7 1.0 5.1e-34 117.1 1.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56237.1 - 2.1e-13 50.1 0.2 2.6e-13 49.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF56237.1 - 3.7e-06 26.5 0.2 4.7e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OWF56237.1 - 0.0015 18.2 1.6 0.07 12.9 1.6 2.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OWF56237.1 - 0.0034 17.4 0.1 0.0064 16.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OWF56237.1 - 0.011 16.1 0.3 0.028 14.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 OWF56237.1 - 0.019 14.4 0.1 0.029 13.8 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OWF56237.1 - 0.028 13.9 0.1 0.063 12.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 OWF56237.1 - 0.043 13.3 0.9 0.25 10.9 0.9 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OWF56237.1 - 0.048 13.4 0.6 2.9 7.6 0.1 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OWF56237.1 - 0.057 13.8 0.1 0.07 13.5 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OWF56237.1 - 0.079 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 OWF56237.1 - 0.084 12.9 0.1 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 OWF56237.1 - 0.093 12.7 0.2 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OWF56237.1 - 0.13 12.2 0.8 2.2 8.2 0.1 2.4 1 1 2 3 3 3 0 RsgA GTPase TniB PF05621.11 OWF56237.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 OWF56238.1 - 4.9e-55 185.5 0.1 5.8e-55 185.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56238.1 - 2.4e-34 118.1 0.0 3.6e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56238.1 - 2.2e-15 56.6 0.1 2.7e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OWF56238.1 - 3.1e-07 30.0 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OWF56238.1 - 3.8e-07 29.7 0.0 6.9e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF56238.1 - 5.3e-06 26.5 0.1 1e-05 25.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF56238.1 - 0.00034 20.2 0.3 0.01 15.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OWF56238.1 - 0.0006 19.6 0.1 0.015 15.1 0.0 2.6 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OWF56238.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 OWF56238.1 - 0.015 15.2 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF2275 PF10039.9 OWF56239.1 - 0.025 14.7 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) EphA2_TM PF14575.6 OWF56239.1 - 1 10.3 4.3 0.99 10.3 2.9 1.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2275 PF10039.9 OWF56240.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) EphA2_TM PF14575.6 OWF56240.1 - 2.1 9.3 5.3 0.87 10.5 2.6 1.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Dimer_Tnp_hAT PF05699.14 OWF56242.1 - 1.8e-11 43.7 0.9 2.3e-11 43.3 0.8 1.3 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region RIX1 PF08167.12 OWF56242.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis NDK PF00334.19 OWF56243.1 - 1.3e-52 177.4 0.0 1.8e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 OWF56243.1 - 0.082 13.5 0.0 0.082 13.5 0.0 1.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ GDI PF00996.18 OWF56244.1 - 5.4e-59 199.8 0.0 1.6e-43 148.9 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OWF56244.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RabGAP-TBC PF00566.18 OWF56245.1 - 1.1e-39 136.4 0.0 2.5e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 OWF56245.1 - 6.3e-33 114.3 0.0 1.8e-32 112.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56245.1 - 3e-19 69.3 0.0 1.1e-18 67.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF56245.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OWF56245.1 - 0.0019 17.2 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF4458 PF14660.6 OWF56246.1 - 0.019 15.2 0.7 0.019 15.2 0.7 4.4 4 2 0 4 4 4 0 Domain of unknown function (DUF4458) DUF2605 PF10792.9 OWF56246.1 - 0.068 13.1 0.3 0.068 13.1 0.3 4.4 5 1 0 5 5 5 0 Protein of unknown function (DUF2605) Nucleoporin_FG2 PF15967.5 OWF56247.1 - 1.2e-105 354.3 92.9 7.6e-102 341.8 92.9 3.1 1 1 0 1 1 1 1 Nucleoporin FG repeated region CEP63 PF17045.5 OWF56247.1 - 0.022 14.7 4.3 0.022 14.7 3.5 1.4 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa DUF1664 PF07889.12 OWF56247.1 - 0.058 13.4 0.7 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 OWF56247.1 - 0.09 12.6 3.6 0.084 12.7 1.1 1.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TBCA PF02970.16 OWF56247.1 - 0.52 10.7 3.7 1.2 9.5 3.7 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A TatD_DNase PF01026.21 OWF56248.1 - 8.6e-05 22.0 0.0 9.6e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 OWF56248.1 - 0.042 13.6 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase LicD PF04991.13 OWF56249.1 - 5.1e-08 33.3 0.1 1.4e-05 25.4 0.0 2.9 4 0 0 4 4 4 2 LicD family I-set PF07679.16 OWF56250.1 - 2.8e-06 27.3 0.0 8.8e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF56250.1 - 6.7e-06 26.6 0.0 3.5e-05 24.3 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain Pox_A14 PF05767.12 OWF56250.1 - 0.0027 17.8 0.0 0.0079 16.3 0.0 1.8 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Death PF00531.22 OWF56250.1 - 0.0048 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Death domain DUF2207 PF09972.9 OWF56250.1 - 0.0071 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) V-set PF07686.17 OWF56250.1 - 0.0073 16.5 0.2 0.031 14.5 0.2 2.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 OWF56250.1 - 0.0089 16.2 0.0 0.043 14.0 0.0 2.2 1 0 0 1 1 1 1 Immunoglobulin domain Podoplanin PF05808.11 OWF56250.1 - 0.17 12.0 4.8 0.048 13.8 0.8 2.2 2 0 0 2 2 2 0 Podoplanin AA_permease_C PF13906.6 OWF56250.1 - 0.24 11.5 1.4 0.49 10.5 1.4 1.5 1 0 0 1 1 1 0 C-terminus of AA_permease Mucin15 PF15672.5 OWF56251.1 - 0.019 14.4 0.1 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 NCD3G PF07562.14 OWF56251.1 - 0.1 12.6 18.3 2.2 8.3 5.7 3.6 1 1 2 3 3 3 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 OWF56251.1 - 0.64 10.5 25.8 0.06 13.7 2.9 4.4 2 1 2 4 4 4 0 TNFR/NGFR cysteine-rich region TMEM154 PF15102.6 OWF56251.1 - 0.73 9.7 0.0 0.73 9.7 0.0 2.7 2 1 1 3 3 3 0 TMEM154 protein family DUF5082 PF16888.5 OWF56252.1 - 9.5e-05 22.7 3.3 0.00037 20.7 0.2 2.5 3 0 0 3 3 2 1 Domain of unknown function (DUF5082) Transposase_22 PF02994.14 OWF56252.1 - 0.0015 18.7 2.1 0.0031 17.6 2.1 1.5 1 0 0 1 1 1 1 L1 transposable element RBD-like domain DUF724 PF05266.14 OWF56252.1 - 0.0064 16.3 0.7 0.0064 16.3 0.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF724) bZIP_1 PF00170.21 OWF56252.1 - 0.0073 16.4 0.1 0.0073 16.4 0.1 2.6 3 0 0 3 3 3 1 bZIP transcription factor GAS PF13851.6 OWF56252.1 - 0.011 15.0 2.8 0.011 15.0 2.8 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 OWF56252.1 - 0.012 15.5 5.7 0.087 12.6 3.8 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF294_C PF10335.9 OWF56252.1 - 0.02 14.7 0.3 0.048 13.4 0.1 1.8 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain DUF1192 PF06698.11 OWF56252.1 - 0.021 14.9 5.4 0.11 12.5 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) BRE1 PF08647.11 OWF56252.1 - 0.027 14.5 1.6 0.048 13.7 0.1 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4795 PF16043.5 OWF56252.1 - 0.061 12.9 3.0 0.11 12.1 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Syntaxin-6_N PF09177.11 OWF56252.1 - 0.075 13.6 2.9 0.16 12.5 1.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FAM76 PF16046.5 OWF56252.1 - 0.13 11.6 1.4 0.15 11.4 0.3 1.7 1 1 0 1 1 1 0 FAM76 protein bZIP_2 PF07716.15 OWF56252.1 - 0.16 12.1 0.1 0.16 12.1 0.1 3.6 2 2 2 4 4 4 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 OWF56252.1 - 0.2 12.0 2.2 5.1 7.4 1.8 2.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 OWF56252.1 - 0.24 11.2 1.9 0.91 9.3 0.0 2.6 2 1 1 3 3 2 0 Septum formation initiator HIP1_clath_bdg PF16515.5 OWF56252.1 - 0.24 12.0 3.9 0.67 10.6 1.1 2.5 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 OWF56252.1 - 0.26 11.7 5.2 0.48 10.9 0.2 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OWF56252.1 - 0.39 10.8 3.3 0.35 10.9 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rabaptin PF03528.15 OWF56252.1 - 0.71 8.5 9.4 0.065 11.9 4.3 1.7 2 0 0 2 2 2 0 Rabaptin DUF1640 PF07798.11 OWF56252.1 - 0.71 9.9 6.5 1.7 8.6 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4200 PF13863.6 OWF56252.1 - 1.3 9.5 6.8 0.15 12.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CdvA PF18822.1 OWF56252.1 - 3.1 7.7 9.0 0.22 11.4 1.4 2.6 3 1 0 3 3 3 0 CdvA-like coiled-coil domain KELK PF15796.5 OWF56253.1 - 0.0013 19.2 64.6 0.95 10.0 3.6 8.4 1 1 11 12 12 12 9 KELK-motif containing domain of MRCK Ser/Thr protein kinase Phage_sheath_1N PF17481.2 OWF56253.1 - 0.0095 16.4 31.7 1.8e+04 -23.2 31.5 11.6 1 1 0 1 1 0 0 Phage tail sheath protein beta-sandwich domain Sec34 PF04136.15 OWF56253.1 - 0.033 14.1 121.8 8 6.3 8.9 10.4 1 1 12 13 13 13 0 Sec34-like family CALCOCO1 PF07888.11 OWF56253.1 - 0.12 11.2 85.8 10 4.9 19.1 5.7 1 1 4 5 5 5 0 Calcium binding and coiled-coil domain (CALCOCO1) like Syntaxin PF00804.25 OWF56253.1 - 0.19 11.4 119.1 0.8 9.3 17.6 6.1 1 1 5 6 6 6 0 Syntaxin APG6_N PF17675.1 OWF56253.1 - 0.31 11.6 79.6 38 4.8 1.1 6.7 1 1 5 6 6 6 0 Apg6 coiled-coil region DUF4201 PF13870.6 OWF56253.1 - 0.31 10.8 98.7 4.2 7.1 6.4 11.1 1 1 12 13 13 13 0 Domain of unknown function (DUF4201) Myosin_tail_1 PF01576.19 OWF56253.1 - 0.41 8.4 89.9 1.5 6.5 36.2 2.9 1 1 0 2 2 2 0 Myosin tail IFT57 PF10498.9 OWF56253.1 - 0.59 9.1 136.4 11 4.9 24.9 6.0 1 1 5 6 6 6 0 Intra-flagellar transport protein 57 DUF3552 PF12072.8 OWF56253.1 - 5.7 6.3 60.6 5.6 6.3 3.5 7.9 1 1 9 10 10 10 0 Domain of unknown function (DUF3552) Jnk-SapK_ap_N PF09744.9 OWF56253.1 - 7.3 6.8 135.2 3.8 7.7 9.4 9.1 1 1 7 9 9 9 0 JNK_SAPK-associated protein-1 Mago_nashi PF02792.14 OWF56254.1 - 4.9e-78 260.1 0.2 5.5e-78 260.0 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein WD40 PF00400.32 OWF56255.1 - 2.4e-39 132.6 3.2 4e-09 37.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF56255.1 - 3.2e-12 46.6 0.1 0.1 12.9 0.0 5.1 1 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OWF56255.1 - 4.1e-08 32.9 2.5 1.7e-05 24.3 0.1 2.2 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.11 OWF56255.1 - 5.3e-08 33.0 0.1 3.5e-05 23.8 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF5046 PF16465.5 OWF56255.1 - 0.0022 17.5 0.5 2.9 7.2 0.2 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) Nup160 PF11715.8 OWF56255.1 - 0.019 13.6 0.2 0.6 8.7 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Emaravirus_P4 PF16505.5 OWF56255.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily FAM101 PF15068.6 OWF56256.1 - 1.7e-06 28.1 27.6 0.15 12.0 3.2 4.8 1 1 5 6 6 6 6 FAM101 family DUF4288 PF14119.6 OWF56256.1 - 4.9e-05 23.7 11.2 29 5.2 0.1 7.3 3 3 6 9 9 9 1 Domain of unknown function (DUF4288) Acetyltransf_4 PF13420.7 OWF56256.1 - 0.00026 21.1 10.0 4.5 7.4 0.1 6.8 1 1 6 7 7 7 2 Acetyltransferase (GNAT) domain LolA_like PF17131.4 OWF56256.1 - 0.00075 19.3 17.3 2.7 7.7 0.3 6.1 1 1 6 7 7 7 5 Outer membrane lipoprotein-sorting protein Cadherin-like PF12733.7 OWF56256.1 - 0.002 18.6 10.2 1.5 9.4 0.3 5.4 1 1 4 5 5 5 2 Cadherin-like beta sandwich domain CDC27 PF09507.10 OWF56256.1 - 2.9 7.2 8.9 1.6e+02 1.4 0.0 5.9 4 2 0 6 6 6 0 DNA polymerase subunit Cdc27 CM2 PF03021.14 OWF56257.1 - 9.6e-05 22.2 2.8 8.1 6.3 0.0 4.9 1 1 4 5 5 5 1 Influenza C virus M2 protein LolA_like PF17131.4 OWF56257.1 - 0.00024 20.9 6.8 0.0028 17.4 1.8 2.1 1 1 2 3 3 3 3 Outer membrane lipoprotein-sorting protein Big_3_4 PF13754.6 OWF56257.1 - 0.038 13.7 0.6 1.6 8.5 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function Adeno_knob PF00541.17 OWF56257.1 - 0.044 13.5 4.5 1 9.0 1.4 2.7 1 1 2 3 3 3 0 Adenoviral fibre protein (knob domain) Cadherin-like PF12733.7 OWF56257.1 - 0.064 13.8 5.7 1.8 9.2 1.1 2.8 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain FAM101 PF15068.6 OWF56257.1 - 0.066 13.2 3.9 0.063 13.2 1.2 1.9 1 1 0 2 2 2 0 FAM101 family Mrr_cat_2 PF13156.6 OWF56257.1 - 0.072 13.0 2.9 14 5.6 0.1 3.4 1 1 2 3 3 3 0 Restriction endonuclease CDC27 PF09507.10 OWF56257.1 - 1 8.7 4.5 18 4.6 0.0 3.9 1 1 2 5 5 5 0 DNA polymerase subunit Cdc27 DUF3947 PF13135.6 OWF56257.1 - 1.5 9.1 14.6 8.4 6.7 1.6 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3947) Toluene_X PF03349.16 OWF56258.1 - 0.00018 20.2 0.0 0.086 11.4 0.0 3.3 3 1 1 4 4 4 3 Outer membrane protein transport protein (OMPP1/FadL/TodX) YadA_anchor PF03895.15 OWF56258.1 - 0.0021 18.1 0.2 11 6.2 0.1 3.8 2 1 0 3 3 3 2 YadA-like membrane anchor domain Surface_Ag_2 PF01617.17 OWF56258.1 - 0.012 15.0 0.2 31 3.9 0.0 3.8 5 0 0 5 5 5 0 Surface antigen Albumin_I PF08027.11 OWF56258.1 - 0.15 11.7 11.9 8.5 6.1 0.3 6.0 5 2 1 6 6 6 0 Albumin I chain b Phage_TAC_10 PF10963.8 OWF56259.1 - 5.5e-07 29.7 0.0 5.9 7.1 0.0 4.8 1 1 4 5 5 5 3 Phage tail assembly chaperone BRCT_2 PF16589.5 OWF56259.1 - 0.0093 16.4 4.9 37 4.8 0.1 4.8 1 1 3 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain MTCP1 PF08991.10 OWF56259.1 - 0.012 15.8 15.8 46 4.3 0.0 7.2 1 1 7 8 8 8 0 Mature-T-Cell Proliferation I type zf-PHD-like PF15446.6 OWF56259.1 - 2.8 7.5 11.0 38 3.8 0.1 3.9 1 1 3 4 4 4 0 PHD/FYVE-zinc-finger like domain SNF PF00209.18 OWF56260.1 - 3.9e-24 85.3 4.8 4.5e-24 85.0 4.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF56261.1 - 2e-64 218.2 18.8 2.3e-64 218.0 18.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 OWF56262.1 - 1e-130 436.9 36.9 1e-130 436.9 36.9 2.3 3 0 0 3 3 3 1 Sodium:neurotransmitter symporter family Na_Ca_ex PF01699.24 OWF56262.1 - 4.2e-51 172.9 46.7 9.9e-28 97.0 21.0 4.8 4 1 0 4 4 4 2 Sodium/calcium exchanger protein Pkinase PF00069.25 OWF56263.1 - 3.9e-70 236.2 0.0 6.3e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56263.1 - 1e-35 123.3 0.0 1.4e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 OWF56263.1 - 8.1e-25 86.5 22.7 3e-12 46.2 4.7 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 OWF56263.1 - 1.2e-08 34.7 0.0 2.9e-08 33.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like C1_2 PF03107.16 OWF56263.1 - 2.8e-08 33.9 16.5 0.00065 20.0 5.6 2.5 2 0 0 2 2 2 2 C1 domain PH PF00169.29 OWF56263.1 - 6.4e-07 29.8 0.1 1.5e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 OWF56263.1 - 2.6e-05 23.7 0.0 5.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 OWF56263.1 - 0.053 13.4 18.4 0.81 9.6 7.1 2.5 2 0 0 2 2 2 0 PHD-finger RIO1 PF01163.22 OWF56263.1 - 0.12 11.9 0.3 0.26 10.8 0.3 1.5 1 0 0 1 1 1 0 RIO1 family PHD_2 PF13831.6 OWF56263.1 - 0.17 11.5 6.7 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 PHD-finger APH PF01636.23 OWF56263.1 - 0.17 11.8 0.0 0.54 10.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-RING-like PF08746.11 OWF56263.1 - 1.4 9.3 19.4 1.4 9.3 3.2 2.6 2 0 0 2 2 2 0 RING-like domain FYVE_2 PF02318.16 OWF56263.1 - 2.1 8.6 14.4 0.65 10.2 3.6 2.9 3 0 0 3 3 3 0 FYVE-type zinc finger TMEM173 PF15009.6 OWF56264.1 - 1.4e-36 126.2 0.1 1.9e-21 76.5 0.1 2.2 2 0 0 2 2 2 2 Transmembrane protein 173 TIR_2 PF13676.6 OWF56264.1 - 5e-17 62.6 0.0 6.5e-11 42.9 0.0 2.9 3 0 0 3 3 3 2 TIR domain TIR PF01582.20 OWF56264.1 - 5.3e-09 36.1 0.1 3.2e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 TIR domain TIR-like PF10137.9 OWF56264.1 - 0.00097 19.1 0.0 0.16 11.9 0.0 3.0 2 0 0 2 2 2 1 Predicted nucleotide-binding protein containing TIR-like domain TMEM173 PF15009.6 OWF56265.1 - 8e-98 327.2 0.0 2.4e-28 99.2 0.1 4.2 4 0 0 4 4 4 4 Transmembrane protein 173 TIR_2 PF13676.6 OWF56265.1 - 3.8e-45 153.3 1.3 4.7e-15 56.2 0.1 4.6 4 0 0 4 4 4 4 TIR domain TIR PF01582.20 OWF56265.1 - 2.8e-15 56.6 3.4 2.3e-06 27.5 0.0 3.4 3 0 0 3 3 3 2 TIR domain TIR-like PF10137.9 OWF56265.1 - 2.7e-09 37.0 1.6 0.0052 16.7 0.0 3.9 3 0 0 3 3 3 3 Predicted nucleotide-binding protein containing TIR-like domain IKKbetaNEMObind PF12179.8 OWF56265.1 - 0.11 12.6 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DUF2007 PF09413.10 OWF56265.1 - 0.17 12.1 0.0 40 4.5 0.0 3.4 3 0 0 3 3 3 0 Putative prokaryotic signal transducing protein Caudal_act PF04731.12 OWF56265.1 - 0.25 11.7 0.4 3.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Caudal like protein activation region DUF4062 PF13271.6 OWF56265.1 - 0.26 11.7 2.5 4 7.9 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4062) TRAM_LAG1_CLN8 PF03798.16 OWF56266.1 - 4.8e-39 134.2 31.8 5.6e-39 133.9 28.5 2.0 2 0 0 2 2 2 1 TLC domain Homeodomain PF00046.29 OWF56266.1 - 1.1e-09 38.0 0.6 2.4e-09 36.9 0.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF56266.1 - 0.0019 18.0 0.5 0.0046 16.8 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OWF56266.1 - 0.0021 17.5 1.7 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Caveolin PF01146.17 OWF56266.1 - 1.4 8.9 7.5 0.41 10.6 3.4 2.1 3 0 0 3 3 3 0 Caveolin TRAM_LAG1_CLN8 PF03798.16 OWF56267.1 - 3.9e-32 111.6 20.9 6.2e-32 110.9 20.9 1.3 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 OWF56267.1 - 2e-11 43.5 0.7 3.6e-11 42.7 0.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OWF56267.1 - 3.5e-05 23.6 0.7 9.3e-05 22.3 0.7 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OWF56267.1 - 0.0028 17.1 0.1 0.0028 17.1 0.1 2.0 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez TRAM_LAG1_CLN8 PF03798.16 OWF56268.1 - 1.3e-34 119.7 30.6 1.9e-34 119.1 30.6 1.3 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 OWF56268.1 - 1.9e-07 30.8 0.4 4.5e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 OWF56268.1 - 0.0061 16.0 0.7 0.096 12.2 0.0 2.4 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 OWF56268.1 - 0.085 12.8 0.5 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain EGF_2 PF07974.13 OWF56269.1 - 0.0084 16.5 1.6 0.019 15.3 1.6 1.7 1 1 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 OWF56269.1 - 0.016 15.3 3.2 0.02 15.0 3.2 1.3 1 0 0 1 1 1 0 Laminin EGF domain Lig_chan-Glu_bd PF10613.9 OWF56270.1 - 2.5e-30 105.0 0.0 1.3e-28 99.4 0.0 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 OWF56270.1 - 1.2e-28 99.9 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 OWF56270.1 - 1.8e-24 86.4 0.0 3.9e-24 85.3 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 OWF56270.1 - 3.7e-07 29.6 0.1 1.2e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region zf-TRAF PF02176.18 OWF56271.1 - 1.6e-17 63.9 25.7 4.8e-09 36.8 4.1 3.4 3 1 0 3 3 3 2 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 OWF56271.1 - 1.1e-07 31.9 4.2 1.1e-07 31.9 4.2 3.4 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OWF56271.1 - 1.2e-07 31.6 8.5 1.2e-07 31.6 8.5 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF56271.1 - 2.4e-07 30.5 7.0 2.4e-07 30.5 7.0 4.6 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF56271.1 - 5.9e-07 29.3 5.6 5.9e-07 29.3 5.6 3.7 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OWF56271.1 - 5.3e-05 23.5 5.5 5.3e-05 23.5 5.5 4.4 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OWF56271.1 - 0.00013 21.9 5.9 0.00013 21.9 5.9 3.8 3 1 1 4 4 4 1 zinc-RING finger domain Sina PF03145.16 OWF56271.1 - 0.00025 21.0 22.2 0.049 13.6 1.2 3.6 1 1 3 4 4 4 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 OWF56271.1 - 0.00037 20.9 32.6 0.0012 19.3 6.9 4.5 2 1 4 6 6 6 4 TRAF-like zinc-finger Porin_3 PF01459.22 OWF56272.1 - 1.5e-77 260.7 9.4 1.7e-77 260.5 9.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin PAP2_C PF14360.6 OWF56273.1 - 2.1e-22 79.5 13.6 2.1e-22 79.5 13.6 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 OWF56273.1 - 3.9e-14 52.8 0.2 7e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF56273.1 - 3e-06 27.2 0.2 5.4e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 OWF56273.1 - 0.00014 21.6 0.2 0.00034 20.4 0.1 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF56273.1 - 0.00023 21.0 0.1 0.0005 20.0 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF4017 PF13209.6 OWF56273.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4017) PAP2 PF01569.21 OWF56273.1 - 4.9 6.9 16.2 0.16 11.7 9.4 2.0 2 1 0 2 2 2 0 PAP2 superfamily Tmem26 PF09772.9 OWF56274.1 - 2e-84 283.4 18.7 2.4e-84 283.1 18.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 DUF4636 PF15468.6 OWF56274.1 - 0.03 14.1 0.2 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) ECSCR PF15820.5 OWF56274.1 - 0.05 13.4 0.0 0.05 13.4 0.0 3.0 4 0 0 4 4 4 0 Endothelial cell-specific chemotaxis regulator FAM163 PF15069.6 OWF56274.1 - 0.064 13.7 0.3 0.23 11.9 0.1 1.9 2 0 0 2 2 2 0 FAM163 family VirB3 PF05101.13 OWF56274.1 - 6.2 7.1 9.3 2.6 8.4 0.1 3.4 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Tmemb_170 PF10190.9 OWF56274.1 - 8.2 6.9 11.7 0.22 11.9 2.4 2.9 2 0 0 2 2 2 0 Putative transmembrane protein 170 Pkinase_Tyr PF07714.17 OWF56275.1 - 2.2e-44 151.7 0.0 3.7e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF56275.1 - 2.8e-40 138.3 0.0 5.6e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Dynamin_N PF00350.23 OWF56275.1 - 1.7e-19 70.5 0.0 4.8e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OWF56275.1 - 5.8e-08 32.8 0.0 2e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC1 PF03109.16 OWF56275.1 - 0.00053 20.2 1.4 0.027 14.6 0.0 3.2 3 0 0 3 3 3 1 ABC1 family IIGP PF05049.13 OWF56275.1 - 0.005 15.9 0.0 0.023 13.8 0.0 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 OWF56275.1 - 0.009 15.4 1.2 0.4 10.0 0.0 3.2 3 0 0 3 3 3 1 AIG1 family Mt_ATP_synt PF15704.5 OWF56275.1 - 0.0098 15.8 3.0 3.1 7.7 0.2 2.7 2 0 0 2 2 2 2 Mitochondrial ATP synthase subunit Septin PF00735.18 OWF56275.1 - 0.012 14.9 0.0 0.31 10.3 0.0 2.6 3 0 0 3 3 3 0 Septin Kinase-like PF14531.6 OWF56275.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1640 PF07798.11 OWF56275.1 - 0.018 15.1 0.5 0.045 13.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) RsgA_GTPase PF03193.16 OWF56275.1 - 0.027 14.4 0.3 0.66 9.9 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase Gp-FAR-1 PF05823.12 OWF56275.1 - 0.039 14.3 2.5 0.42 10.9 0.0 3.1 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) 7tm_1 PF00001.21 OWF56276.1 - 4.5e-12 45.8 1.3 5.3e-12 45.6 1.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TctB PF07331.11 OWF56276.1 - 0.026 14.8 0.8 0.034 14.4 0.8 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family TMEM138 PF14935.6 OWF56276.1 - 1.6 9.4 9.2 3.5 8.3 0.9 2.1 1 1 1 2 2 2 0 Transmembrane protein 138 7tm_1 PF00001.21 OWF56277.1 - 1.5e-45 155.6 20.3 2e-45 155.2 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SGTA_dimer PF16546.5 OWF56278.1 - 1.6e-05 24.5 0.0 39 4.1 0.0 6.8 6 3 3 9 9 9 0 Homodimerisation domain of SGTA RPS31 PF17067.5 OWF56278.1 - 0.014 15.5 3.9 4.3 7.6 0.0 4.4 1 1 3 5 5 5 0 Ribosomal protein S31e DUF723 PF05265.13 OWF56278.1 - 0.057 13.4 24.9 25 4.9 0.1 7.5 2 2 5 8 8 8 0 Protein of unknown function (DUF723) zf-C3HC4_4 PF15227.6 OWF56278.1 - 0.21 11.8 9.8 1.2e+02 3.0 0.0 6.6 7 0 0 7 7 7 0 zinc finger of C3HC4-type, RING HHH PF00633.23 OWF56278.1 - 4.1 7.5 9.7 99 3.1 0.0 5.3 5 0 0 5 5 5 0 Helix-hairpin-helix motif C1q PF00386.21 OWF56279.1 - 1.1e-20 74.1 0.4 1.6e-20 73.6 0.4 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF56279.1 - 8.2e-06 25.8 0.1 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 BclA C-terminal domain DUF3585 PF12130.8 OWF56279.1 - 0.0011 19.1 0.4 0.0015 18.6 0.4 1.1 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain K-cyclin_vir_C PF09080.10 OWF56281.1 - 0.0012 19.3 0.4 47 4.5 0.0 5.1 2 1 1 5 5 5 2 K cyclin, C terminal Fasciclin PF02469.22 OWF56282.1 - 4.1e-111 366.5 1.4 8.6e-20 71.3 0.0 7.1 7 0 0 7 7 7 7 Fasciclin domain RTT107_BRCT_6 PF16771.5 OWF56282.1 - 1.3 9.2 4.3 5.9 7.1 0.1 3.6 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain DEAD PF00270.29 OWF56283.1 - 0.018 14.8 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 OWF56283.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ResIII PF04851.15 OWF56284.1 - 8.3e-21 74.7 0.1 3.6e-20 72.7 0.1 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.8 OWF56284.1 - 2e-18 66.7 1.1 4.5e-18 65.6 1.1 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I DEAD PF00270.29 OWF56284.1 - 2.1e-18 66.7 0.2 9.5e-18 64.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF56284.1 - 1.5e-13 51.0 0.6 1.2e-12 48.2 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RIG-I_C PF18119.1 OWF56284.1 - 6.5e-12 45.7 3.7 7.6e-12 45.4 0.6 2.9 2 1 0 2 2 2 1 RIG-I receptor C-terminal domain SWI2_SNF2 PF18766.1 OWF56284.1 - 9.1e-05 22.2 0.1 0.00021 21.0 0.1 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Death PF00531.22 OWF56284.1 - 0.0033 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Death domain DUF3638 PF12340.8 OWF56284.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) AAA_22 PF13401.6 OWF56284.1 - 0.063 13.6 0.0 0.25 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OWF56284.1 - 0.087 13.2 0.2 0.24 11.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain Pentapeptide_2 PF01469.18 OWF56284.1 - 0.37 10.7 7.4 0.69 9.9 7.4 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) ResIII PF04851.15 OWF56285.1 - 4.9e-19 69.0 1.2 1.7e-18 67.2 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OWF56285.1 - 2.8e-18 66.3 0.2 2e-17 63.5 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase RIG-I_C-RD PF11648.8 OWF56285.1 - 2.2e-16 60.2 8.8 5.5e-16 58.8 8.8 1.7 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.31 OWF56285.1 - 2.6e-14 53.5 0.2 8.1e-14 51.9 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RIG-I_C PF18119.1 OWF56285.1 - 1.2e-11 44.8 1.3 1.2e-11 44.8 1.3 2.7 3 1 0 3 3 3 1 RIG-I receptor C-terminal domain SWI2_SNF2 PF18766.1 OWF56285.1 - 0.00079 19.2 0.0 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 OWF56285.1 - 0.00083 19.7 0.0 0.0028 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Death PF00531.22 OWF56285.1 - 0.0024 18.0 0.1 0.0076 16.4 0.1 1.8 1 0 0 1 1 1 1 Death domain ParBc_2 PF08857.11 OWF56285.1 - 0.064 13.3 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Putative ParB-like nuclease Glyco_tran_WbsX PF14307.6 OWF56285.1 - 0.23 10.9 1.6 8.2 5.8 0.0 2.5 1 1 0 2 2 2 0 Glycosyltransferase WbsX LRR_8 PF13855.6 OWF56286.1 - 2.8e-93 305.6 64.9 1.1e-15 57.1 2.1 11.5 4 2 7 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 OWF56286.1 - 5.1e-47 157.1 62.1 2.6e-06 27.7 0.2 12.0 8 4 3 12 12 12 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OWF56286.1 - 6.1e-47 158.8 20.6 1.6e-10 41.1 1.1 5.2 1 1 6 7 7 7 7 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 OWF56286.1 - 1e-22 80.5 33.0 1.7e-06 27.6 2.4 6.7 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 OWF56286.1 - 1.1e-07 31.4 68.8 4.1 8.3 0.0 19.0 19 3 0 19 19 19 5 Leucine Rich Repeat Trypsin PF00089.26 OWF56286.1 - 0.00029 20.7 0.1 0.00074 19.4 0.1 1.6 1 1 0 1 1 1 1 Trypsin eIF-6 PF01912.18 OWF56286.1 - 0.054 12.9 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 eIF-6 family ATXN-1_C PF12547.8 OWF56287.1 - 4.8 7.6 6.8 14 6.1 0.3 2.7 2 1 1 3 3 3 0 Capicua transcriptional repressor modulator Pkinase_Tyr PF07714.17 OWF56288.1 - 2.8e-34 118.6 0.2 7.2e-34 117.2 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF56288.1 - 6e-26 91.4 0.1 1.3e-25 90.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain PBP_like_2 PF12849.7 OWF56288.1 - 5.2e-22 78.8 1.8 7.2e-22 78.4 1.8 1.2 1 0 0 1 1 1 1 PBP superfamily domain Guanylate_cyc PF00211.20 OWF56288.1 - 1.8e-14 53.8 0.0 3.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PBP_like_2 PF12849.7 OWF56289.1 - 6e-08 32.7 0.0 6.5e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 PBP superfamily domain Glyco_transf_10 PF00852.19 OWF56290.1 - 5e-45 153.4 2.2 8.7e-45 152.6 2.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 OWF56290.1 - 2.6e-19 69.7 0.1 6.2e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal DUF1570 PF07607.11 OWF56290.1 - 0.14 12.4 0.2 0.27 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) ADD_ATRX PF17981.1 OWF56291.1 - 0.0032 17.3 17.7 2.4 8.1 0.0 8.0 10 0 0 10 10 10 3 Cysteine Rich ADD domain Vps36-NZF-N PF16988.5 OWF56291.1 - 0.15 11.5 2.9 15 5.1 0.4 4.5 5 1 0 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Tn7_Tnp_TnsA_C PF08721.11 OWF56292.1 - 0.093 13.4 1.6 22 5.8 0.1 2.9 2 1 1 3 3 3 0 TnsA endonuclease C terminal DUF5001 PF16392.5 OWF56293.1 - 6.4e-05 22.8 67.1 15 5.5 1.6 17.4 1 1 16 17 17 17 17 Ig-like domain Transglut_C PF00927.22 OWF56293.1 - 0.00027 21.1 73.1 4.6 7.4 0.3 16.3 1 1 16 18 18 18 15 Transglutaminase family, C-terminal ig like domain AID PF18767.1 OWF56294.1 - 0.00033 20.6 2.8 4.5 7.3 0.1 5.1 1 1 2 5 5 5 2 Activation induced deaminase Colicin_E5 PF12106.8 OWF56294.1 - 0.017 15.4 4.1 5.5 7.4 0.1 4.6 2 2 2 5 5 5 0 Colicin E5 ribonuclease domain BRX_assoc PF16627.5 OWF56294.1 - 1 9.5 14.3 5.4 7.2 0.0 5.8 5 2 1 7 7 7 0 Unstructured region between BRX_N and BRX domain EF-hand_7 PF13499.6 OWF56296.1 - 3.9e-22 78.5 4.2 2.3e-14 53.6 0.2 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF56296.1 - 1.6e-20 71.1 10.9 4.1e-07 29.1 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF56296.1 - 4.5e-18 63.6 5.2 5.4e-06 25.9 0.2 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF56296.1 - 4.7e-15 54.3 6.5 3.3e-05 23.2 0.4 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OWF56296.1 - 5.2e-12 45.4 10.1 2.1e-05 24.3 0.4 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 OWF56296.1 - 5.1e-05 23.2 4.7 0.48 10.4 0.1 3.5 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56296.1 - 0.0002 21.6 3.7 0.026 14.9 0.3 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DAG_kinase_N PF14513.6 OWF56296.1 - 0.02 15.1 0.1 0.03 14.5 0.1 1.6 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Homez PF11569.8 OWF56296.1 - 0.098 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EF-hand_10 PF14788.6 OWF56296.1 - 0.24 11.3 4.5 13 5.7 0.3 3.3 4 1 0 4 4 4 0 EF hand EF-hand_7 PF13499.6 OWF56297.1 - 8.6e-28 96.6 4.3 3e-17 62.8 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF56297.1 - 1.7e-25 86.6 6.7 6.4e-08 31.6 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF56297.1 - 3.5e-23 79.5 2.7 5.4e-07 29.0 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF56297.1 - 5.7e-20 69.8 7.1 4.3e-06 26.0 0.1 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OWF56297.1 - 3.3e-19 68.5 7.9 8.5e-08 31.9 0.2 3.9 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF56297.1 - 3.3e-06 27.4 0.5 0.018 15.3 0.1 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF56297.1 - 9.7e-05 22.3 1.2 1.2 9.1 0.0 3.5 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF56297.1 - 0.00033 20.9 0.1 0.024 15.0 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain DUF1679 PF07914.11 OWF56297.1 - 0.0056 15.6 0.2 0.45 9.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 OWF56297.1 - 0.027 14.3 2.0 5.5 6.9 0.0 3.2 4 0 0 4 4 4 0 EF hand Dockerin_1 PF00404.18 OWF56297.1 - 0.068 13.4 0.2 18 5.6 0.0 2.7 2 1 1 3 3 3 0 Dockerin type I domain Urease_alpha PF00449.20 OWF56298.1 - 0.00077 19.8 0.8 70 3.8 0.0 5.1 1 1 5 6 6 6 0 Urease alpha-subunit, N-terminal domain Ubiquitin_2 PF14560.6 OWF56298.1 - 0.072 13.6 5.1 82 3.8 0.1 4.3 1 1 4 5 5 5 0 Ubiquitin-like domain LAX PF15681.5 OWF56298.1 - 7 5.4 19.2 12 4.6 7.8 2.5 1 1 1 2 2 2 0 Lymphocyte activation family X Thioredoxin PF00085.20 OWF56299.1 - 1.6e-29 101.9 1.2 1.8e-29 101.7 1.2 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OWF56299.1 - 5.9e-09 35.7 0.1 6.7e-09 35.5 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OWF56299.1 - 3.1e-07 30.8 0.4 5.7e-07 30.0 0.4 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OWF56299.1 - 5.3e-07 29.9 0.1 6.7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.16 OWF56299.1 - 1.6e-06 27.9 0.5 1.7e-06 27.8 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 OWF56299.1 - 1e-05 25.6 0.1 1.3e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OWF56299.1 - 0.00012 22.0 0.2 0.00016 21.6 0.2 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OWF56299.1 - 0.00013 21.8 0.2 0.00014 21.7 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 OWF56299.1 - 0.0024 17.6 0.3 0.0035 17.1 0.3 1.3 1 1 0 1 1 1 1 Redoxin TraF PF13728.6 OWF56299.1 - 0.008 16.0 0.0 0.0094 15.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 OWF56299.1 - 0.014 15.3 0.3 0.7 9.8 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain DUF2847 PF11009.8 OWF56299.1 - 0.034 14.1 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HyaE PF07449.11 OWF56299.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 OWF56299.1 - 0.13 12.5 1.9 0.46 10.7 1.7 2.2 1 1 0 1 1 1 0 Glutaredoxin KaiB PF07689.12 OWF56299.1 - 0.18 11.6 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiB domain ATG11 PF10377.9 OWF56300.1 - 1.2e-12 48.0 0.0 1.2e-12 48.0 0.0 5.6 7 0 0 7 7 7 1 Autophagy-related protein 11 Golgin_A5 PF09787.9 OWF56300.1 - 0.00023 20.7 24.7 0.00023 20.7 24.7 7.3 3 1 3 7 7 7 1 Golgin subfamily A member 5 TBK1_ULD PF18396.1 OWF56300.1 - 0.00039 20.3 0.0 0.0023 17.8 0.0 2.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain PKcGMP_CC PF16808.5 OWF56300.1 - 0.0026 17.6 3.1 0.0026 17.6 3.1 7.6 7 1 0 7 7 7 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bMG3 PF11974.8 OWF56300.1 - 1.2 9.2 6.1 0.27 11.3 0.2 2.9 3 0 0 3 3 3 0 Bacterial alpha-2-macroglobulin MG3 domain PNPase_C PF12111.8 OWF56300.1 - 3.4 7.2 8.7 1.1 8.7 2.3 2.4 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal GCM PF03615.15 OWF56301.1 - 1.9e-71 238.4 3.3 1.9e-71 238.4 3.3 2.4 3 0 0 3 3 3 1 GCM motif protein SYCP2_SLD PF18584.1 OWF56302.1 - 5e-21 75.0 0.0 4e-20 72.1 0.0 2.7 2 0 0 2 2 2 1 Synaptonemal complex 2 Spt16M-like domain Cor1 PF04803.12 OWF56302.1 - 1.5e-13 51.1 17.9 1.5e-13 51.1 17.9 5.3 4 1 0 5 5 5 1 Cor1/Xlr/Xmr conserved region Guanylate_cyc PF00211.20 OWF56303.1 - 3.4e-64 215.8 0.0 6.6e-64 214.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF56303.1 - 6.9e-37 127.1 0.0 1.2e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF56303.1 - 7.5e-35 120.6 0.0 1.3e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF56303.1 - 4.1e-05 23.1 0.6 6.3e-05 22.5 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated AP_endonuc_2 PF01261.24 OWF56304.1 - 2.5e-05 23.8 0.0 0.0027 17.2 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel UPRTase PF14681.6 OWF56305.1 - 4.7e-67 225.4 0.1 7.7e-67 224.7 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 OWF56305.1 - 2.8e-61 206.7 0.0 4.3e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OWF56305.1 - 1.9e-07 31.7 0.0 4.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 OWF56305.1 - 9.5e-06 25.6 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CoaE PF01121.20 OWF56305.1 - 0.00098 18.8 0.2 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_33 PF13671.6 OWF56305.1 - 0.0023 18.1 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OWF56305.1 - 0.0035 17.8 0.5 0.13 12.7 0.5 2.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OWF56305.1 - 0.08 12.7 0.8 4.1 7.1 0.0 2.8 2 1 1 3 3 3 0 Cytidylate kinase AAA PF00004.29 OWF56305.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNX17_FERM_C PF18116.1 OWF56305.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain PMG PF05287.12 OWF56306.1 - 1.5e-12 47.9 153.9 0.013 15.6 14.3 10.2 1 1 8 9 9 9 8 PMG protein Keratin_B2 PF01500.17 OWF56306.1 - 8.1e-07 29.2 22.2 1.9 8.5 0.6 7.8 1 1 4 5 5 5 5 Keratin, high sulfur B2 protein 6PF2K PF01591.18 OWF56307.1 - 0.11 11.8 0.3 0.25 10.6 0.3 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Peptidase_M28 PF04389.17 OWF56308.1 - 4.5e-42 144.0 0.0 6.1e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OWF56308.1 - 2.2e-05 24.2 0.0 5.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 zf-RanBP PF00641.18 OWF56309.1 - 1.7e-16 59.2 19.6 1.1e-08 34.2 4.3 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 OWF56309.1 - 0.021 14.7 6.0 0.57 10.1 1.5 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) SAPS PF04499.15 OWF56309.1 - 0.089 11.6 6.1 0.12 11.2 6.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DZR PF12773.7 OWF56309.1 - 0.23 11.5 8.9 0.94 9.5 1.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OWF56309.1 - 0.32 10.8 8.1 1.3 8.8 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Nop14 PF04147.12 OWF56309.1 - 0.8 7.8 10.0 0.96 7.6 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family RecR PF02132.15 OWF56309.1 - 5.2 6.7 8.8 0.69 9.5 1.5 2.3 2 0 0 2 2 2 0 RecR protein Metallothi_Euk2 PF12809.7 OWF56309.1 - 6.3 7.1 12.0 14 6.1 3.1 2.3 1 1 1 2 2 2 0 Eukaryotic metallothionein LRR_6 PF13516.6 OWF56310.1 - 8.7e-10 37.9 3.1 0.0033 17.3 0.1 3.7 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 OWF56310.1 - 0.011 16.1 1.5 0.48 10.9 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF56310.1 - 0.034 13.9 2.4 1.5 8.7 2.4 2.9 1 1 1 2 2 2 0 Leucine rich repeat DUF1410 PF07198.11 OWF56311.1 - 3.9e-06 27.3 10.2 42 4.7 0.0 7.9 9 0 0 9 9 9 0 Protein of unknown function (DUF1410) Luteo_PO PF04662.13 OWF56311.1 - 9.1e-06 25.5 0.0 2.2 7.9 0.0 3.8 1 1 5 6 6 6 4 Luteovirus P0 protein HflK_N PF12221.8 OWF56311.1 - 0.00039 20.4 0.0 35 4.5 0.0 6.4 9 0 0 9 9 9 0 Bacterial membrane protein N terminal Flavodoxin_3 PF12641.7 OWF56311.1 - 0.00049 19.8 0.3 1.7 8.4 0.0 2.7 1 1 2 3 3 3 3 Flavodoxin domain Med2 PF11214.8 OWF56311.1 - 0.011 15.8 0.1 5.3 7.3 0.0 2.8 1 1 1 2 2 2 0 Mediator complex subunit 2 IGR PF09597.10 OWF56311.1 - 1.5 9.0 22.5 12 6.1 0.8 5.4 1 1 4 6 6 6 0 IGR protein motif zf-C2H2 PF00096.26 OWF56312.1 - 2.3e-19 68.7 26.3 0.00052 20.3 0.7 6.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OWF56312.1 - 4.8e-12 45.7 21.3 3.6e-05 24.0 0.5 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF56312.1 - 2.8e-07 30.8 27.3 0.017 15.9 0.2 6.5 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OWF56312.1 - 0.00038 20.7 6.1 0.12 12.6 0.9 3.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 OWF56312.1 - 0.003 18.1 0.2 0.003 18.1 0.2 5.7 2 1 4 6 6 5 1 FOXP coiled-coil domain zf-met PF12874.7 OWF56312.1 - 0.015 15.7 3.7 4.1 7.9 0.1 3.3 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 OWF56312.1 - 0.051 13.7 12.8 3.9 7.6 0.8 4.6 2 1 1 4 4 4 0 Aberrant zinc-finger EpoR_lig-bind PF09067.10 OWF56312.1 - 0.097 12.9 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding zf-C2H2_6 PF13912.6 OWF56312.1 - 0.38 10.8 5.0 1.9 8.6 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OWF56312.1 - 1.4 9.3 13.7 18 5.8 0.2 4.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 OWF56312.1 - 3.8 8.3 18.5 9.8 7.0 0.7 4.6 3 1 1 4 4 4 0 CHORD PDZ PF00595.24 OWF56313.1 - 4.3e-16 59.0 0.0 6.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OWF56313.1 - 2.7e-09 36.7 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OWF56313.1 - 7e-07 29.5 0.0 9.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Ndc1_Nup PF09531.10 OWF56314.1 - 9.6e-80 269.0 17.9 2.1e-79 267.9 17.9 1.5 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RFX_DNA_binding PF02257.15 OWF56315.1 - 1.1e-33 115.7 0.0 3.5e-33 114.0 0.0 2.0 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 OWF56315.1 - 0.007 16.8 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Poxvirus D5 protein-like IL10 PF00726.17 OWF56315.1 - 0.065 12.7 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Interleukin 10 PQ-loop PF04193.14 OWF56316.1 - 2.2e-35 120.2 22.7 1.7e-19 69.3 1.0 3.0 3 0 0 3 3 3 2 PQ loop repeat Ank_2 PF12796.7 OWF56317.1 - 4.5e-24 84.8 3.5 3.9e-15 56.2 0.4 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF56317.1 - 6.7e-18 64.5 2.2 2.1e-08 34.2 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF56317.1 - 1.7e-15 57.2 0.7 3.7e-10 40.1 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56317.1 - 8e-15 53.5 0.3 0.0023 18.3 0.0 4.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OWF56317.1 - 1.3e-14 53.9 0.5 0.0015 18.9 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat RTT107_BRCT_5 PF16770.5 OWF56317.1 - 1.2e-06 28.4 0.0 4.8e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 OWF56317.1 - 9.2e-05 22.8 0.0 0.00058 20.2 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OWF56317.1 - 0.00064 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 OWF56317.1 - 0.001 19.4 0.0 0.012 16.0 0.0 2.8 4 0 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain FAST_1 PF06743.15 OWF56317.1 - 1.6 8.7 5.6 14 5.7 0.4 3.8 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 RINGv PF12906.7 OWF56318.1 - 6e-15 55.1 4.2 1.1e-14 54.3 4.2 1.4 1 0 0 1 1 1 1 RING-variant domain PHO4 PF01384.20 OWF56318.1 - 0.039 13.0 0.1 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphate transporter family zf-RING_4 PF14570.6 OWF56318.1 - 0.078 12.8 3.3 0.28 11.0 3.3 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1240 PF06836.12 OWF56318.1 - 0.12 12.9 1.8 0.23 12.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) zf-RING_2 PF13639.6 OWF56318.1 - 0.85 10.0 11.5 0.11 12.9 6.1 2.3 2 1 1 3 3 3 0 Ring finger domain zf-ANAPC11 PF12861.7 OWF56318.1 - 1.1 9.3 7.8 1.4 9.0 6.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sushi PF00084.20 OWF56319.1 - 4.9e-292 942.9 248.9 6.6e-12 45.9 1.9 37.7 37 0 0 37 37 37 35 Sushi repeat (SCR repeat) Ephrin_rec_like PF07699.13 OWF56319.1 - 1.3e-38 130.5 56.3 6.6e-12 45.0 5.7 6.7 5 1 1 6 6 6 4 Putative ephrin-receptor like VWA PF00092.28 OWF56319.1 - 1.2e-30 107.0 0.0 2.1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 OWF56319.1 - 1.8e-30 104.9 104.2 1.2e-07 31.8 6.1 12.4 8 0 0 8 8 7 6 EGF-like domain HYR PF02494.16 OWF56319.1 - 3.8e-28 97.6 7.6 4.3e-14 52.6 0.0 3.9 4 0 0 4 4 3 2 HYR domain Pentaxin PF00354.17 OWF56319.1 - 8.4e-20 71.3 0.4 1.3e-19 70.6 0.4 1.3 1 0 0 1 1 1 1 Pentaxin family hEGF PF12661.7 OWF56319.1 - 1.1e-16 60.8 97.6 5.6e-05 23.6 5.2 13.6 11 1 0 11 11 9 6 Human growth factor-like EGF VWA_2 PF13519.6 OWF56319.1 - 2.3e-11 44.3 0.0 4.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_3 PF13385.6 OWF56319.1 - 3.1e-11 43.7 9.5 6.5e-11 42.6 9.5 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily HRM PF02793.22 OWF56319.1 - 2.6e-07 30.8 179.5 0.079 13.3 0.3 29.8 29 3 3 32 32 30 10 Hormone receptor domain EGF_CA PF07645.15 OWF56319.1 - 0.0012 18.9 6.4 0.0012 18.9 6.4 17.6 15 2 2 17 17 15 5 Calcium-binding EGF domain cEGF PF12662.7 OWF56319.1 - 0.0076 16.2 1.3 0.0076 16.2 1.3 26.9 32 0 0 32 32 32 3 Complement Clr-like EGF-like VWA_3 PF13768.6 OWF56319.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain EGF_2 PF07974.13 OWF56319.1 - 0.12 12.8 123.3 0.016 15.5 11.1 11.3 8 0 0 8 8 7 0 EGF-like domain Arm PF00514.23 OWF56321.1 - 6.4e-06 26.0 0.0 0.2 11.7 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 OWF56322.1 - 1.5e-74 250.7 0.0 2.7e-74 249.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56322.1 - 5.3e-43 147.2 0.0 7.6e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 OWF56322.1 - 2.4e-14 53.8 0.3 1.6e-13 51.1 0.1 2.5 2 1 1 3 3 3 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 OWF56322.1 - 2.3e-06 27.2 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OWF56322.1 - 0.0016 18.1 0.7 0.0029 17.2 0.7 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OWF56322.1 - 0.011 14.7 0.4 0.021 13.7 0.4 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OWF56322.1 - 0.059 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OWF56322.1 - 0.092 12.6 0.6 0.27 11.1 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family ABC_membrane_2 PF06472.15 OWF56323.1 - 4.6e-96 321.4 3.8 6.1e-96 321.0 3.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OWF56323.1 - 9.1e-17 61.9 0.0 2.1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF56323.1 - 0.00026 20.5 0.7 0.3 10.5 0.1 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OWF56323.1 - 0.0052 17.3 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OWF56323.1 - 0.031 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OWF56323.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OWF56323.1 - 0.07 12.7 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OWF56323.1 - 0.079 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OWF56323.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 OWF56323.1 - 0.12 11.7 0.4 0.34 10.3 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OWF56323.1 - 0.13 12.3 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OWF56323.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain UPF0139 PF03669.13 OWF56324.1 - 3.2e-44 148.7 0.8 4e-44 148.4 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) ShK PF01549.24 OWF56325.1 - 6.4e-05 23.4 7.0 8.2e-05 23.1 7.0 1.2 1 0 0 1 1 1 1 ShK domain-like EMI PF07546.13 OWF56327.1 - 0.067 14.0 12.1 0.12 13.2 11.5 1.8 1 1 1 2 2 2 0 EMI domain ArfGap PF01412.18 OWF56328.1 - 4e-40 136.5 0.3 5e-40 136.2 0.3 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NDC10_II PF16787.5 OWF56328.1 - 0.043 12.9 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 partial_CstF PF15861.5 OWF56328.1 - 0.051 13.4 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain DUF2797 PF10977.8 OWF56328.1 - 0.086 12.7 0.1 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) Rubredoxin_2 PF18073.1 OWF56328.1 - 0.16 11.7 1.5 1.2 8.9 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain CLP_protease PF00574.23 OWF56329.1 - 6.5e-66 221.7 0.0 7.9e-66 221.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease SAS-6_N PF16531.5 OWF56330.1 - 1.3e-27 96.2 1.4 1.3e-27 96.2 1.4 2.5 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal Sas6_CC PF18594.1 OWF56330.1 - 3.4e-13 49.1 1.9 3.4e-13 49.1 1.9 3.8 4 0 0 4 4 4 1 Sas6/XLF/XRCC4 coiled-coil domain VGPC1_C PF16799.5 OWF56330.1 - 0.019 15.0 5.1 0.45 10.5 0.2 4.2 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Spc7 PF08317.11 OWF56330.1 - 1.7 7.5 64.8 0.13 11.1 16.5 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 OWF56330.1 - 1.8 9.0 58.2 0.2 12.1 16.7 3.4 1 1 2 3 3 3 0 Fez1 DUF4407 PF14362.6 OWF56330.1 - 2.6 7.3 40.9 1.8e+04 -9.5 40.9 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 OWF56330.1 - 8.4 6.6 66.2 9.7 6.4 18.6 4.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) LPP PF04728.13 OWF56330.1 - 8.7 6.8 9.9 21 5.6 0.0 4.8 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF812 PF05667.11 OWF56330.1 - 9.1 5.0 60.6 2.4 6.9 40.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Profilin PF00235.19 OWF56331.1 - 7.8e-13 48.8 0.1 8.7e-13 48.7 0.1 1.0 1 0 0 1 1 1 1 Profilin Ank_4 PF13637.6 OWF56332.1 - 9.3e-20 70.7 2.3 3.5e-09 37.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OWF56332.1 - 1.5e-19 70.3 0.1 1.8e-12 47.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OWF56332.1 - 4.6e-17 61.9 1.0 2.2e-07 31.0 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56332.1 - 2.5e-10 39.7 1.1 0.0026 18.1 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OWF56332.1 - 1.2e-08 35.0 2.2 0.0038 17.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Pro_isomerase PF00160.21 OWF56333.1 - 5e-44 150.3 0.3 2.5e-43 148.1 0.0 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SRP-alpha_N PF04086.13 OWF56334.1 - 2.3 8.1 48.6 2.7 7.8 48.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal 7tm_1 PF00001.21 OWF56335.1 - 2.7e-54 184.3 23.8 3.3e-54 184.0 23.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF56335.1 - 1.1e-09 38.1 23.2 6.5e-09 35.5 23.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF56335.1 - 4.3e-08 33.1 20.2 4.3e-08 33.1 20.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 OWF56335.1 - 7.2e-06 25.6 21.6 0.00015 21.2 21.5 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 OWF56335.1 - 0.0014 18.0 27.8 0.0054 16.1 0.1 3.0 1 1 2 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 OWF56335.1 - 0.0056 16.4 19.7 0.0087 15.8 15.7 2.1 2 0 0 2 2 2 1 Olfactory receptor TMEM154 PF15102.6 OWF56335.1 - 0.033 14.1 2.5 0.21 11.5 0.1 2.6 1 1 1 2 2 2 0 TMEM154 protein family DUF2116 PF09889.9 OWF56335.1 - 4.6 7.3 7.0 9.6 6.3 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) MFS_1 PF07690.16 OWF56336.1 - 5.3e-12 45.3 9.7 1.1e-11 44.3 9.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily SLATT_fungal PF18142.1 OWF56336.1 - 0.2 11.6 1.7 6.4 6.8 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain RNA_pol_Rpb1_5 PF04998.17 OWF56337.1 - 4.9e-98 327.8 0.1 3.2e-97 325.1 0.1 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OWF56337.1 - 1e-69 234.0 1.0 1.8e-69 233.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OWF56337.1 - 4.6e-31 107.9 0.0 1.4e-30 106.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OWF56337.1 - 4.1e-26 92.0 4.0 2.7e-25 89.4 0.2 3.7 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OWF56337.1 - 1.4e-21 76.5 0.0 7.2e-21 74.2 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF4820 PF16091.5 OWF56337.1 - 6 6.2 12.9 6.3 6.1 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) JAB PF01398.21 OWF56338.1 - 5.9e-18 65.0 0.1 1.1e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ocular_alb PF02101.15 OWF56339.1 - 1.2e-17 63.9 9.6 1.6e-17 63.5 9.6 1.1 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_1 PF00001.21 OWF56339.1 - 0.0052 16.1 5.9 0.0052 16.1 5.9 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Reo_sigmaC PF04582.12 OWF56339.1 - 0.028 14.7 0.3 0.066 13.5 0.1 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain Galactosyl_T PF01762.21 OWF56340.1 - 6.5e-40 137.0 0.0 9.4e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 OWF56340.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Fringe-like TGF_beta PF00019.20 OWF56341.1 - 6.6e-22 78.5 5.0 6.6e-22 78.5 5.0 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 OWF56341.1 - 1.9e-10 40.9 1.5 1.5e-09 37.9 1.5 2.0 1 1 0 1 1 1 1 TGF-beta propeptide Cys_knot PF00007.22 OWF56341.1 - 0.75 10.1 6.9 0.067 13.5 1.9 1.9 2 0 0 2 2 2 0 Cystine-knot domain FAM91_C PF14648.6 OWF56343.1 - 2.9e-163 543.7 0.2 5.1e-163 542.9 0.2 1.3 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 OWF56343.1 - 1.9e-143 477.4 2.4 2.5e-143 477.0 2.4 1.2 1 0 0 1 1 1 1 FAM91 N-terminus EF-hand_7 PF13499.6 OWF56344.1 - 2.7e-20 72.6 5.3 2.1e-13 50.5 1.8 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF56344.1 - 1.1e-19 68.4 14.7 7.6e-08 31.4 1.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OWF56344.1 - 6.6e-17 59.9 9.4 3.2e-05 23.5 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF56344.1 - 1.3e-15 56.1 10.2 1.4e-05 24.3 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OWF56344.1 - 4.7e-15 55.2 8.2 8.1e-06 25.6 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OWF56344.1 - 2.3e-06 27.9 1.0 0.00028 21.2 1.0 3.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF56344.1 - 0.026 14.5 0.9 0.66 10.0 0.0 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF56344.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 OWF56344.1 - 0.055 13.7 0.6 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_2 PF09068.11 OWF56344.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 EF hand Acetyltransf_10 PF13673.7 OWF56345.1 - 9.2e-11 41.8 0.1 2.3e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OWF56345.1 - 5.4e-10 39.5 0.0 1.2e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PARP PF00644.20 OWF56345.1 - 6.9e-10 38.8 0.0 6.9e-10 38.8 0.0 2.5 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain Acetyltransf_7 PF13508.7 OWF56345.1 - 4.8e-06 26.9 0.1 1e-05 25.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 OWF56345.1 - 0.0093 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ PH_2 PF08458.10 OWF56345.1 - 0.014 15.7 1.1 0.044 14.1 1.1 1.8 1 0 0 1 1 1 0 Plant pleckstrin homology-like region FR47 PF08445.10 OWF56345.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF4820 PF16091.5 OWF56345.1 - 0.3 10.4 8.4 0.73 9.2 8.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FlgT_M PF16539.5 OWF56346.1 - 0.48 10.5 5.1 0.58 10.3 1.7 2.2 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain WD40 PF00400.32 OWF56347.1 - 1.7e-16 60.3 21.2 1.1e-07 32.4 1.5 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF56347.1 - 1.7e-07 31.4 0.2 0.0035 17.6 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_alt PF14077.6 OWF56347.1 - 0.016 15.1 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif PQQ_3 PF13570.6 OWF56347.1 - 0.027 15.0 0.9 0.41 11.2 0.1 3.2 3 0 0 3 3 3 0 PQQ-like domain Ge1_WD40 PF16529.5 OWF56347.1 - 0.064 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein 7tm_1 PF00001.21 OWF56348.1 - 3.1e-35 121.8 20.2 3.8e-35 121.5 20.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF56348.1 - 5.1e-11 42.7 22.0 7.8e-11 42.1 22.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF56348.1 - 0.00025 20.9 14.9 0.00055 19.8 14.9 1.6 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF56348.1 - 0.00038 19.9 17.9 0.0007 19.1 17.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 OWF56348.1 - 1.3 8.5 19.6 16 4.9 19.6 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc DUF4407 PF14362.6 OWF56348.1 - 1.5 8.1 3.5 0.82 9.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) 7tm_1 PF00001.21 OWF56349.1 - 2e-33 115.8 15.1 2.6e-33 115.5 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF56349.1 - 1.1e-09 38.3 16.7 2.9e-09 37.0 16.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF56349.1 - 3.1e-08 33.3 15.3 4.4e-08 32.8 15.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 OWF56349.1 - 8.6e-05 22.2 12.6 0.00014 21.5 12.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Sru PF10322.9 OWF56349.1 - 0.0012 18.3 8.9 0.0021 17.4 8.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru COesterase PF00135.28 OWF56350.1 - 3.6e-134 448.4 0.0 4.2e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OWF56350.1 - 2.9e-05 24.0 0.6 8.7e-05 22.5 0.6 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OWF56350.1 - 0.00015 21.3 0.1 0.0003 20.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OWF56350.1 - 0.0076 16.9 0.7 0.012 16.2 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family S4 PF01479.25 OWF56350.1 - 0.037 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 S4 domain HTH_27 PF13463.6 OWF56351.1 - 7.3e-18 64.8 24.1 13 6.4 0.0 22.2 19 5 9 30 30 30 8 Winged helix DNA-binding domain Endonuclease_NS PF01223.23 OWF56352.1 - 2.7e-55 187.7 0.0 3.9e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Exog_C PF18026.1 OWF56352.1 - 6.9e-09 35.6 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain PARP PF00644.20 OWF56353.1 - 3.7e-19 69.1 0.2 1.5e-18 67.1 0.2 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UBA_4 PF14555.6 OWF56353.1 - 0.0063 16.3 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ART-PolyVal PF18760.1 OWF56353.1 - 0.092 13.8 0.0 0.31 12.1 0.0 1.9 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins zf-C2H2_3rep PF18868.1 OWF56355.1 - 0.025 15.3 0.1 0.026 15.2 0.1 1.1 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF2651 PF10852.8 OWF56357.1 - 0.0005 20.6 14.8 4 8.1 7.0 4.9 1 1 3 4 4 4 2 Protein of unknown function (DUF2651) PAH PF02671.21 OWF56357.1 - 0.014 15.5 0.0 11 6.2 0.2 4.5 4 1 1 5 5 5 0 Paired amphipathic helix repeat DUF1731 PF08338.11 OWF56357.1 - 0.046 13.5 0.9 57 3.7 0.0 4.4 5 1 1 6 6 6 0 Domain of unknown function (DUF1731) MHC2-interact PF09307.10 OWF56357.1 - 0.34 10.9 3.7 14 5.8 0.2 3.1 1 1 1 3 3 3 0 CLIP, MHC2 interacting Pestivirus_E2 PF16329.5 OWF56357.1 - 2.5 6.8 11.3 3.1 6.6 5.8 2.5 1 1 1 2 2 2 0 Pestivirus envelope glycoprotein E2 NTP_transferase PF00483.23 OWF56358.1 - 2e-12 47.3 0.0 2.9e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OWF56358.1 - 8.4e-11 42.5 0.0 1.5e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 OWF56358.1 - 2.9e-06 26.8 5.5 0.0021 17.7 0.9 3.8 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 OWF56358.1 - 0.00063 18.0 1.0 0.00063 18.0 1.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 OWF56358.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 OWF56358.1 - 0.11 11.5 5.0 0.38 9.7 4.9 1.8 1 1 0 1 1 1 0 L-fucokinase SAM_1 PF00536.30 OWF56359.1 - 8.9e-14 51.7 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OWF56359.1 - 5e-10 39.3 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 OWF56359.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ribosomal_L29 PF00831.23 OWF56360.1 - 1.7 8.6 5.0 0.74 9.8 0.6 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein 7tm_1 PF00001.21 OWF56361.1 - 5.2e-50 170.2 11.6 9.9e-50 169.3 11.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 OWF56361.1 - 1.6e-07 31.4 10.8 1.6e-07 31.4 10.8 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 OWF56361.1 - 0.00071 19.0 21.0 0.0041 16.5 14.3 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF56361.1 - 0.0021 17.8 22.1 0.0021 17.8 22.1 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2046 PF09755.9 OWF56362.1 - 0.00054 19.3 0.2 0.00065 19.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF677 PF05055.12 OWF56362.1 - 0.0053 15.7 0.1 0.0055 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) TMF_TATA_bd PF12325.8 OWF56362.1 - 0.036 14.3 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 OWF56362.1 - 0.064 13.4 1.3 0.1 12.8 0.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LPP PF04728.13 OWF56362.1 - 0.088 13.2 0.5 0.18 12.2 0.5 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Vps51 PF08700.11 OWF56362.1 - 0.1 12.7 2.0 0.13 12.4 1.1 1.6 2 0 0 2 2 2 0 Vps51/Vps67 TatD_DNase PF01026.21 OWF56363.1 - 1.4e-15 57.4 0.0 1.7e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase UPF0259 PF06790.11 OWF56364.1 - 0.065 13.0 1.0 0.074 12.8 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0259) Lectin_C PF00059.21 OWF56365.1 - 8.6e-180 586.2 89.5 1.9e-20 73.6 0.4 13.6 13 1 0 13 13 13 12 Lectin C-type domain ShK PF01549.24 OWF56365.1 - 3.5e-12 46.7 25.6 3.5e-08 33.8 5.6 4.1 3 0 0 3 3 3 2 ShK domain-like UL45 PF05473.12 OWF56365.1 - 9.9e-11 41.6 21.6 0.19 11.4 0.1 11.2 9 2 2 11 11 11 3 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 OWF56365.1 - 3.2e-05 24.2 9.6 3.3 8.2 0.1 9.1 10 1 1 11 11 11 1 Extracellular link domain Chordopox_A33R PF05966.12 OWF56365.1 - 0.0002 20.7 10.2 1.8 7.8 0.1 6.2 6 0 0 6 6 6 2 Chordopoxvirus A33R protein Sporozoite_P67 PF05642.11 OWF56365.1 - 6.3 4.7 5.9 11 3.9 5.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2 PF00096.26 OWF56366.1 - 4.6e-25 86.6 34.5 1.9e-06 28.0 1.0 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OWF56366.1 - 5.8e-20 70.3 32.4 8.5e-05 23.1 0.9 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OWF56366.1 - 6e-19 67.5 36.3 2e-07 31.1 0.4 5.7 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OWF56366.1 - 3.8e-12 46.2 15.5 0.0039 17.4 0.0 5.4 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OWF56366.1 - 1.1e-08 35.1 19.0 0.025 15.0 0.2 5.6 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OWF56366.1 - 5e-08 32.7 30.4 0.011 15.8 1.5 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OWF56366.1 - 0.0021 18.2 21.8 0.072 13.2 3.4 4.9 4 2 1 5 5 5 3 Zinc ribbon domain zf-C2HC_2 PF13913.6 OWF56366.1 - 0.0045 16.9 15.1 1.4 8.9 1.3 5.0 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 OWF56366.1 - 0.0075 16.0 29.3 0.18 11.6 0.3 5.4 5 0 0 5 5 5 3 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 OWF56366.1 - 0.011 16.5 0.8 0.011 16.5 0.8 3.3 2 1 0 2 2 2 0 zinc-ribbon family zf-BED PF02892.15 OWF56366.1 - 0.026 14.5 0.3 0.026 14.5 0.3 5.0 2 2 3 5 5 5 0 BED zinc finger zf-C2HE PF16278.5 OWF56366.1 - 0.054 14.0 0.3 0.054 14.0 0.3 4.5 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 OWF56366.1 - 0.17 11.8 16.1 14 5.7 2.6 5.0 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HypA PF01155.19 OWF56366.1 - 0.21 11.6 14.8 1.3 9.0 0.5 3.6 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 OWF56366.1 - 0.34 11.3 18.1 2.9 8.3 0.6 4.5 1 1 4 5 5 4 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 OWF56366.1 - 1.1 9.4 16.2 0.92 9.6 0.6 3.2 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 OWF56366.1 - 2.4 8.4 30.3 8.7 6.6 0.1 5.8 6 0 0 6 6 5 0 AN1-like Zinc finger XPA_N PF01286.18 OWF56366.1 - 3.2 7.9 19.2 5 7.3 0.3 4.9 5 0 0 5 5 4 0 XPA protein N-terminal Sprouty PF05210.13 OWF56366.1 - 4.8 7.6 16.1 0.28 11.6 1.8 3.0 2 1 0 2 2 2 0 Sprouty protein (Spry) ADK_lid PF05191.14 OWF56366.1 - 6.4 6.8 19.1 26 4.9 2.2 4.5 2 1 2 4 4 4 0 Adenylate kinase, active site lid DUF4585 PF15232.6 OWF56368.1 - 3.3 7.8 23.6 4.6 7.4 0.0 8.6 9 5 2 11 11 11 0 Domain of unknown function (DUF4585) L_HMGIC_fpl PF10242.9 OWF56369.1 - 1e-05 25.9 3.6 1.6e-05 25.2 3.6 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Peptidase_U4 PF03419.13 OWF56369.1 - 0.0079 15.5 3.6 0.013 14.8 3.6 1.3 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Claudin_2 PF13903.6 OWF56369.1 - 0.017 14.9 20.2 12 5.6 20.2 3.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3377 PF11857.8 OWF56369.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Amastin PF07344.11 OWF56369.1 - 0.029 14.2 3.9 0.046 13.6 3.7 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein Sm_multidrug_ex PF06695.11 OWF56369.1 - 0.036 14.7 2.0 4.9 7.8 0.7 2.3 2 1 0 2 2 2 0 Putative small multi-drug export protein DUF4064 PF13273.6 OWF56369.1 - 0.24 11.7 16.1 0.27 11.5 0.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Neur_chan_memb PF02932.16 OWF56370.1 - 7.5 6.5 5.1 10 6.1 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PEPCK_GTP PF00821.18 OWF56371.1 - 2.6e-169 562.7 0.5 3.2e-169 562.4 0.5 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 OWF56371.1 - 4.9e-93 310.7 0.0 6.9e-93 310.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Methyltransf_33 PF10017.9 OWF56372.1 - 3.4e-62 210.4 0.0 4.1e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_31 PF13847.6 OWF56372.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 OWF56373.1 - 2.1e-63 214.3 0.0 2.5e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF2013 PF09431.10 OWF56373.1 - 0.0025 18.0 0.2 0.0043 17.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) AMP-binding PF00501.28 OWF56375.1 - 5.7e-28 97.7 0.2 1.2e-18 67.0 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OWF56375.1 - 5e-07 30.6 0.1 8.9e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OWF56376.1 - 1.1e-41 142.9 0.0 1.4e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OWF56376.1 - 1.5e-07 32.3 0.1 2.8e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_21 PF05050.12 OWF56377.1 - 2.6e-12 47.1 0.2 3.6e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain RrnaAD PF00398.20 OWF56377.1 - 0.012 14.7 0.2 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OWF56377.1 - 0.05 13.2 0.4 0.091 12.3 0.4 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_21 PF05050.12 OWF56378.1 - 5.2e-12 46.1 0.1 7.1e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain RrnaAD PF00398.20 OWF56378.1 - 0.011 14.8 0.2 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OWF56378.1 - 0.051 13.1 0.4 0.091 12.3 0.4 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Kringle PF00051.18 OWF56379.1 - 1.9e-22 79.4 17.6 7.1e-13 48.7 9.5 2.8 2 0 0 2 2 2 2 Kringle domain ApoL PF05461.11 OWF56380.1 - 9e-11 41.6 7.1 8.4e-06 25.3 3.7 2.3 2 0 0 2 2 2 2 Apolipoprotein L OTU PF02338.19 OWF56380.1 - 6.6e-06 26.6 0.0 0.58 10.7 0.0 4.0 4 0 0 4 4 4 3 OTU-like cysteine protease CD225 PF04505.12 OWF56381.1 - 8.5e-14 51.4 0.1 1.2e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4064 PF13273.6 OWF56381.1 - 0.013 15.7 1.4 0.019 15.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) ATP1G1_PLM_MAT8 PF02038.16 OWF56381.1 - 9 5.8 6.2 3.2 7.3 0.5 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Aa_trans PF01490.18 OWF56382.1 - 1.1e-57 195.6 32.8 1.3e-57 195.4 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OWF56382.1 - 3.5e-08 32.9 29.5 1.1e-07 31.3 29.5 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Phage_Gp23 PF10669.9 OWF56382.1 - 0.16 12.3 1.1 6.1 7.2 0.0 3.2 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) LHC PF00556.20 OWF56382.1 - 0.32 11.2 0.0 0.32 11.2 0.0 4.2 4 0 0 4 4 4 0 Antenna complex alpha/beta subunit IRS PF02174.17 OWF56383.1 - 2.4e-18 65.9 0.0 4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 OWF56383.1 - 1.7e-05 25.3 0.2 3.2e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF56383.1 - 0.01 16.3 4.1 1.5 9.3 3.5 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain PDDEXK_2 PF12784.7 OWF56383.1 - 0.058 12.9 0.0 0.15 11.6 0.0 1.6 1 1 1 2 2 2 0 PD-(D/E)XK nuclease family transposase Peptidase_U32_C PF16325.5 OWF56384.1 - 0.01 16.1 13.7 59 4.0 0.1 6.1 1 1 4 6 6 6 0 Peptidase family U32 C-terminal domain LolB PF03550.14 OWF56384.1 - 0.015 15.4 0.7 16 5.5 0.0 3.3 1 1 3 4 4 4 0 Outer membrane lipoprotein LolB P_proprotein PF01483.20 OWF56384.1 - 0.42 10.7 5.7 21 5.2 0.2 4.6 1 1 2 3 3 3 0 Proprotein convertase P-domain Myosin_tail_1 PF01576.19 OWF56385.1 - 2.2e-14 52.3 70.9 1.1e-13 50.0 38.5 2.1 1 1 1 2 2 2 2 Myosin tail Tho2 PF11262.8 OWF56385.1 - 0.0023 17.2 6.6 0.0023 17.2 6.6 5.0 1 1 4 5 5 4 1 Transcription factor/nuclear export subunit protein 2 CALCOCO1 PF07888.11 OWF56385.1 - 0.0029 16.6 19.4 0.0029 16.6 19.4 4.0 1 1 3 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 OWF56385.1 - 0.0036 17.9 5.6 0.0036 17.9 5.6 6.1 3 1 3 6 6 6 1 SlyX DUF5082 PF16888.5 OWF56385.1 - 0.011 16.0 12.0 0.011 16.0 12.0 5.1 1 1 3 5 5 5 0 Domain of unknown function (DUF5082) TMEM192 PF14802.6 OWF56385.1 - 0.081 12.0 1.0 0.14 11.3 1.0 1.4 1 0 0 1 1 1 0 TMEM192 family FTHFS PF01268.19 OWF56385.1 - 0.1 10.8 2.0 0.15 10.3 0.1 1.9 2 0 0 2 2 2 0 Formate--tetrahydrofolate ligase DNA_Packaging_2 PF11123.8 OWF56385.1 - 0.43 10.8 5.4 1 9.6 0.3 3.4 3 1 1 4 4 4 0 DNA packaging protein Filament PF00038.21 OWF56385.1 - 0.9 9.1 65.6 0.011 15.3 49.3 3.5 1 1 2 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 OWF56385.1 - 0.95 8.3 66.6 0.027 13.4 21.4 3.9 1 1 2 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 OWF56385.1 - 2.4 8.6 66.5 3.8 7.9 22.6 3.7 1 1 2 3 3 3 0 Fez1 APG6_N PF17675.1 OWF56385.1 - 2.8 8.5 72.1 0.66 10.5 19.4 5.2 1 1 3 5 5 5 0 Apg6 coiled-coil region Img2 PF05046.14 OWF56385.1 - 3.9 7.9 11.2 0.45 10.8 1.1 3.4 1 1 2 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) DUF1640 PF07798.11 OWF56385.1 - 6.9 6.7 64.6 0.46 10.5 14.1 4.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1640) Pribosyltran PF00156.27 OWF56386.1 - 1.2e-18 67.1 0.1 1.5e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OWF56386.1 - 0.0055 16.2 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 OWF56386.1 - 0.032 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase ubiquitin PF00240.23 OWF56387.1 - 9.4e-28 95.8 0.1 1e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OWF56387.1 - 2.2e-16 59.4 0.2 2.4e-16 59.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OWF56387.1 - 6.6e-05 23.3 0.0 0.00019 21.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OWF56387.1 - 0.00015 21.6 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OWF56387.1 - 0.091 12.9 0.1 0.24 11.5 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Collagen PF01391.18 OWF56388.1 - 9.9e-39 130.9 133.3 6.3e-09 35.5 26.4 6.1 1 1 4 5 5 5 5 Collagen triple helix repeat (20 copies) C1q PF00386.21 OWF56388.1 - 1.1e-19 70.9 0.4 1.5e-19 70.5 0.4 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF56388.1 - 7.8e-06 25.8 1.9 1.2e-05 25.2 1.9 1.2 1 0 0 1 1 1 1 BclA C-terminal domain ZapB PF06005.12 OWF56388.1 - 0.094 13.2 0.1 0.14 12.6 0.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapB C1q PF00386.21 OWF56389.1 - 3.9e-15 56.2 0.0 4.4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF56389.1 - 0.042 13.8 1.1 0.05 13.5 1.1 1.1 1 0 0 1 1 1 0 BclA C-terminal domain C1q PF00386.21 OWF56390.1 - 5.4e-20 71.9 0.0 8.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 OWF56390.1 - 3.3e-13 49.2 47.6 2.9e-08 33.3 27.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 OWF56390.1 - 2.5e-06 27.4 1.0 3.8e-06 26.8 1.0 1.3 1 0 0 1 1 1 1 BclA C-terminal domain Crystall_2 PF09076.10 OWF56390.1 - 0.089 12.7 2.9 2.8 7.9 2.9 2.5 1 1 0 1 1 1 0 Beta/Gamma crystallin C1q PF00386.21 OWF56391.1 - 4e-21 75.6 0.1 4.3e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 OWF56391.1 - 1.3e-07 31.6 0.1 1.5e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 BclA C-terminal domain Mab-21 PF03281.14 OWF56392.1 - 2.4e-32 112.4 0.2 4.1e-32 111.7 0.2 1.3 1 0 0 1 1 1 1 Mab-21 protein TPR_2 PF07719.17 OWF56392.1 - 0.0086 16.1 0.1 6.8 7.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Reprolysin PF01421.19 OWF56393.1 - 1.6e-32 113.0 0.2 3.3e-32 112.0 0.2 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_spacer1 PF05986.14 OWF56393.1 - 3.8e-29 101.0 0.0 7.2e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 OWF56393.1 - 1.7e-25 89.8 3.7 1.7e-25 89.8 3.7 2.4 2 1 0 2 2 1 1 Reprolysin family propeptide TSP_1 PF00090.19 OWF56393.1 - 1e-24 86.5 115.6 4.6e-13 49.1 10.1 9.3 10 0 0 10 10 10 5 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 OWF56393.1 - 4.2e-19 68.8 18.4 5.3e-19 68.5 8.8 6.4 5 1 0 5 5 2 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF56393.1 - 1.6e-17 64.3 0.4 3.9e-17 63.0 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OWF56393.1 - 1.4e-11 45.0 0.0 3.4e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF56393.1 - 1.3e-10 41.6 0.1 2.8e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 OWF56393.1 - 6.3e-09 36.4 8.6 6.3e-09 36.4 8.6 2.8 2 0 0 2 2 1 1 PLAC (protease and lacunin) domain Reprolysin_4 PF13583.6 OWF56393.1 - 7.3e-06 25.8 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DNA_primase_S PF01896.19 OWF56393.1 - 0.04 14.0 0.1 0.095 12.7 0.1 1.6 1 0 0 1 1 1 0 DNA primase small subunit Trypan_PARP PF05887.11 OWF56394.1 - 0.0028 17.6 1.6 0.0043 17.0 1.6 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF1971 PF09313.11 OWF56394.1 - 0.5 10.4 2.4 8.3 6.5 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1971) Guanylate_cyc PF00211.20 OWF56395.1 - 7e-60 201.8 0.2 2e-58 197.1 0.0 2.6 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 OWF56395.1 - 4.5e-25 89.5 0.0 6.1e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 OWF56395.1 - 0.00027 20.4 0.1 0.00043 19.8 0.1 1.2 1 0 0 1 1 1 1 Heme NO binding associated TRF PF08558.10 OWF56395.1 - 0.027 14.1 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Peptidase_M14 PF00246.24 OWF56396.1 - 3.4e-84 283.1 1.0 4.4e-84 282.7 1.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OWF56396.1 - 3.9e-13 49.6 0.2 7.4e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide WD40 PF00400.32 OWF56397.1 - 1.6e-17 63.5 1.6 0.00093 20.0 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat SNF PF00209.18 OWF56398.1 - 3.5e-196 653.0 36.8 4.3e-196 652.6 36.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Laminin_EGF PF00053.24 OWF56400.1 - 0.048 13.8 161.0 1.4 9.1 6.5 10.2 1 1 9 10 10 10 0 Laminin EGF domain SKG6 PF08693.10 OWF56400.1 - 0.072 12.5 0.8 0.12 11.8 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F5_F8_type_C PF00754.25 OWF56401.1 - 3.7e-07 30.3 1.2 6.7e-07 29.5 1.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain SKG6 PF08693.10 OWF56401.1 - 0.15 11.5 3.5 0.28 10.6 3.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2607 PF10795.9 OWF56404.1 - 0.98 9.6 8.3 2.5 8.3 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2607) DUF1192 PF06698.11 OWF56405.1 - 0.00011 22.2 0.4 11 6.1 0.0 4.6 2 1 2 4 4 4 3 Protein of unknown function (DUF1192) Dynein_IC2 PF11540.8 OWF56405.1 - 0.00087 19.2 0.1 83 3.3 0.0 5.3 3 1 3 6 6 6 0 Cytoplasmic dynein 1 intermediate chain 2 SSL_OB PF09199.10 OWF56405.1 - 0.017 15.5 0.2 21 5.6 0.0 3.2 1 1 3 4 4 4 0 Staphylococcal superantigen-like OB-fold domain SAB PF04382.13 OWF56405.1 - 0.033 14.3 16.5 23 5.2 1.6 6.6 1 1 5 6 6 6 0 SAB domain NIF3 PF01784.18 OWF56405.1 - 0.23 11.0 2.3 6.2 6.4 0.1 2.6 2 1 0 2 2 2 0 NIF3 (NGG1p interacting factor 3) DUF572 PF04502.13 OWF56406.1 - 1.5e-88 297.6 7.5 2e-88 297.2 7.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) LRR_6 PF13516.6 OWF56407.1 - 7.2e-17 59.9 19.6 0.00023 21.0 0.0 6.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 OWF56407.1 - 0.012 16.0 1.3 11 7.0 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 OWF56407.1 - 0.037 14.5 9.7 0.05 14.0 0.1 4.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OWF56407.1 - 1.5 8.6 14.1 6.7 6.6 1.4 4.8 3 1 1 4 4 4 0 Leucine rich repeat MFS_1 PF07690.16 OWF56408.1 - 1.1e-26 93.6 35.6 5.3e-23 81.5 6.2 2.4 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 OWF56408.1 - 0.00011 21.7 18.5 0.0011 18.3 1.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB CbtA PF09490.10 OWF56408.1 - 0.0096 15.7 0.5 0.03 14.1 0.5 1.8 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) NRDE-2 PF08424.10 OWF56409.1 - 6.6e-87 291.6 3.4 6.6e-87 291.6 3.4 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference DUF4372 PF14294.6 OWF56409.1 - 0.096 12.8 0.1 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) TPR_14 PF13428.6 OWF56409.1 - 0.13 13.1 0.8 31 5.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat RasGEF PF00617.19 OWF56410.1 - 2e-51 174.7 0.2 4.7e-51 173.5 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OWF56410.1 - 1.8e-28 98.8 0.5 5e-28 97.4 0.5 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.20 OWF56410.1 - 8.6e-16 58.7 1.3 8.6e-16 58.7 1.3 2.3 2 1 0 2 2 2 1 RhoGEF domain Histone PF00125.24 OWF56410.1 - 3.2e-12 46.9 0.0 7.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH PF00169.29 OWF56410.1 - 1.1e-11 45.2 0.1 2.5e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 OWF56410.1 - 0.00023 21.4 0.2 0.00057 20.1 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 OWF56410.1 - 0.092 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 PH domain Aida_C2 PF14186.6 OWF56411.1 - 2.9e-55 185.9 0.1 4.3e-55 185.4 0.1 1.3 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 OWF56411.1 - 5.2e-33 113.5 0.0 1.7e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 Aida N-terminus Tecti-min-caps PF09300.10 OWF56411.1 - 0.046 13.8 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Tectiviridae, minor capsid Ras PF00071.22 OWF56412.1 - 8e-15 54.8 0.0 9.4e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56412.1 - 6.8e-10 39.2 0.0 7.7e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 OWF56412.1 - 0.008 16.0 0.0 0.0097 15.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OWF56412.1 - 0.0099 16.3 0.0 0.01 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OWF56412.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OWF56412.1 - 0.027 14.2 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OWF56412.1 - 0.032 14.1 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 OWF56412.1 - 0.045 12.9 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 OWF56412.1 - 0.045 13.7 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OWF56412.1 - 0.067 12.6 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 OWF56412.1 - 0.076 12.5 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OWF56412.1 - 0.096 12.6 0.0 0.096 12.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 OWF56412.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 OWF56413.1 - 8.3e-69 230.3 0.9 2e-60 203.1 0.5 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OWF56413.1 - 4.4e-34 117.3 2.4 1.2e-33 115.8 0.1 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56413.1 - 7e-13 48.4 0.1 1.1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF56413.1 - 2.6e-05 24.2 0.3 0.079 12.9 0.1 3.2 2 1 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OWF56413.1 - 2.7e-05 23.7 0.0 0.013 15.0 0.0 3.1 2 1 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OWF56413.1 - 8.2e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OWF56413.1 - 0.00012 21.7 0.3 0.00026 20.6 0.3 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OWF56413.1 - 0.0057 16.0 0.1 0.009 15.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 OWF56413.1 - 0.0061 17.0 0.0 0.041 14.3 0.0 2.2 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 OWF56413.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain WYL_3 PF18488.1 OWF56413.1 - 0.031 14.6 0.2 12 6.4 0.1 2.4 2 0 0 2 2 2 0 WYL domain AAA_5 PF07728.14 OWF56413.1 - 0.044 13.8 0.0 0.26 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Glyoxalase_5 PF14696.6 OWF56413.1 - 0.077 13.2 0.0 16 5.7 0.0 2.5 1 1 1 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal AAA_16 PF13191.6 OWF56413.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 OWF56413.1 - 0.12 12.5 0.1 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 OWF56413.1 - 0.12 12.6 0.0 0.74 10.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain CmlA_N PF18456.1 OWF56413.1 - 0.16 11.2 0.1 27 4.0 0.0 2.9 2 1 0 3 3 3 0 Diiron non-heme beta-hydroxylase N-terminal domain Ras PF00071.22 OWF56414.1 - 4.5e-59 198.7 0.7 5.4e-59 198.4 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56414.1 - 6.5e-34 116.7 0.2 1.1e-33 115.9 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56414.1 - 2.7e-12 46.5 0.7 3.3e-12 46.2 0.6 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF56414.1 - 4.5e-06 26.7 0.1 8.1e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OWF56414.1 - 0.0002 21.3 0.4 0.16 11.9 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OWF56414.1 - 0.00038 19.9 0.2 0.00043 19.7 0.2 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF56414.1 - 0.0034 17.0 0.3 0.0052 16.4 0.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OWF56414.1 - 0.054 13.8 0.0 0.74 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OWF56414.1 - 0.067 13.6 0.0 0.13 12.6 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OWF56414.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 OWF56414.1 - 0.13 12.3 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ras PF00071.22 OWF56415.1 - 1e-59 200.8 0.8 1.3e-59 200.5 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56415.1 - 2.6e-34 118.0 0.6 4.7e-34 117.2 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56415.1 - 1.2e-09 37.9 0.2 1.8e-09 37.3 0.2 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OWF56415.1 - 7.5e-06 25.9 0.2 0.041 13.8 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OWF56415.1 - 2.3e-05 24.5 0.0 4.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF56415.1 - 0.00046 19.6 0.1 0.00056 19.3 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OWF56415.1 - 0.001 18.7 0.2 0.0029 17.2 0.2 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OWF56415.1 - 0.007 15.9 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.6 OWF56415.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OWF56415.1 - 0.015 15.6 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OWF56415.1 - 0.023 14.4 0.1 0.044 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 OWF56415.1 - 0.032 13.7 0.1 0.059 12.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OWF56415.1 - 0.041 13.4 0.2 0.53 9.8 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 OWF56415.1 - 0.049 13.9 0.0 0.27 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OWF56415.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 OWF56415.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OWF56415.1 - 0.15 11.5 0.0 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein TAF1_subA PF14929.6 OWF56416.1 - 1.8e-47 162.5 1.2 2.3e-47 162.2 1.2 1.1 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A Clathrin PF00637.20 OWF56416.1 - 0.013 15.3 0.4 0.049 13.5 0.1 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Pfg27 PF09216.10 OWF56416.1 - 0.57 10.0 5.5 0.087 12.6 0.6 2.1 3 0 0 3 3 3 0 Pfg27 EF-hand_7 PF13499.6 OWF56417.1 - 6.1e-11 42.6 3.2 8.7e-11 42.1 2.8 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OWF56417.1 - 6.6e-09 35.0 0.7 0.0019 18.0 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OWF56417.1 - 7.7e-06 25.1 0.2 0.0013 18.1 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OWF56417.1 - 0.00073 19.3 1.2 0.0052 16.6 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair MCR_C PF04609.12 OWF56417.1 - 0.028 13.5 0.1 0.052 12.6 0.0 1.5 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C EF-hand_5 PF13202.6 OWF56417.1 - 0.064 12.8 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 EF hand TFIIA PF03153.13 OWF56417.1 - 0.11 12.4 24.8 0.15 12.0 24.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit POTRA_TamA_1 PF17243.2 OWF56417.1 - 0.2 11.7 3.0 0.56 10.3 3.0 1.7 1 0 0 1 1 1 0 POTRA domain TamA domain 1 DUF2057 PF09829.9 OWF56420.1 - 0.18 12.0 2.2 36 4.4 0.3 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SAYSvFN PF10260.9 OWF56423.1 - 4.7e-28 96.9 0.2 6.2e-28 96.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) Orn_DAP_Arg_deC PF00278.22 OWF56423.1 - 0.087 13.1 0.0 0.097 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SUIM_assoc PF16619.5 OWF56423.1 - 0.26 11.4 3.4 0.6 10.2 3.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 UPF0239 PF06783.11 OWF56423.1 - 2.9 8.1 5.9 17 5.7 0.2 2.9 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0239) SAYSvFN PF10260.9 OWF56424.1 - 8.3e-28 96.1 0.3 1.1e-27 95.7 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) Thyroglobulin_1 PF00086.18 OWF56424.1 - 0.022 14.4 0.8 0.031 13.9 0.1 1.6 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat Orn_DAP_Arg_deC PF00278.22 OWF56424.1 - 0.075 13.3 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SUIM_assoc PF16619.5 OWF56424.1 - 0.29 11.2 3.4 0.62 10.2 3.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 COG2 PF06148.11 OWF56425.1 - 8e-40 136.0 2.6 8e-40 136.0 2.6 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 OWF56425.1 - 8e-37 126.4 0.9 2.4e-36 124.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 OWF56425.1 - 0.027 14.6 1.3 0.15 12.2 0.0 2.9 2 1 1 3 3 3 0 Vps51/Vps67 Mis12 PF05859.12 OWF56425.1 - 0.092 12.8 0.4 0.27 11.3 0.4 1.7 1 0 0 1 1 1 0 Mis12 protein CSN8_PSD8_EIF3K PF10075.9 OWF56426.1 - 4.5e-33 114.2 0.1 7e-33 113.6 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Kunitz_BPTI PF00014.23 OWF56427.1 - 1.9e-13 50.4 2.5 2.7e-13 49.9 2.5 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Cornifin PF02389.15 OWF56428.1 - 2.6e-06 27.7 4.8 0.0011 19.2 0.3 2.6 1 1 1 2 2 2 2 Cornifin (SPRR) family Death PF00531.22 OWF56428.1 - 0.0052 16.9 0.9 0.062 13.5 1.0 2.3 2 0 0 2 2 2 1 Death domain Big_2 PF02368.18 OWF56428.1 - 1.1 9.2 7.2 42 4.1 0.0 4.9 4 2 0 4 4 4 0 Bacterial Ig-like domain (group 2) PMT PF02366.18 OWF56429.1 - 1.2e-72 244.5 18.5 1.2e-72 244.5 18.5 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OWF56429.1 - 1.4e-52 178.2 16.1 1.4e-52 178.2 16.1 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OWF56429.1 - 6.7e-23 81.5 0.1 1.3e-22 80.6 0.1 1.4 1 0 0 1 1 1 1 MIR domain EF-hand_1 PF00036.32 OWF56430.1 - 3.3e-38 126.4 9.0 1e-09 37.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56430.1 - 6.6e-33 113.0 1.6 2.8e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF56430.1 - 7.5e-30 102.6 8.6 7.1e-13 48.2 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF56430.1 - 4.8e-27 91.5 5.6 1.7e-09 36.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF56430.1 - 2e-24 84.0 7.3 9.9e-07 28.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56430.1 - 6.2e-14 52.1 0.1 3.5e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56430.1 - 1.9e-07 30.9 0.2 0.017 15.1 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56430.1 - 2.8e-06 27.6 0.0 0.048 14.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF56430.1 - 3.3e-05 23.8 0.0 0.058 13.4 0.0 2.9 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OWF56430.1 - 7.4e-05 23.6 0.0 0.027 15.3 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 OWF56430.1 - 0.00023 21.2 0.7 0.0011 19.0 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OWF56430.1 - 0.0016 18.6 5.0 2.5 8.4 5.0 3.0 1 1 0 1 1 1 1 Dockerin type I domain Caleosin PF05042.13 OWF56430.1 - 0.0028 17.6 0.6 0.99 9.3 0.0 3.3 1 1 2 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 OWF56430.1 - 0.0038 18.0 0.3 1.8 9.4 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 OWF56430.1 - 0.0054 17.1 0.6 2.1 8.7 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF1103 PF06513.11 OWF56430.1 - 0.0055 16.3 1.1 0.0068 16.0 1.1 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.6 OWF56430.1 - 0.0056 17.1 0.0 2.4 8.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) dCache_2 PF08269.11 OWF56430.1 - 0.0062 15.8 0.1 0.38 9.9 0.1 2.2 1 1 1 2 2 2 1 Cache domain TerB PF05099.13 OWF56430.1 - 0.013 15.5 0.2 0.77 9.7 0.1 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB SurA_N_2 PF13623.6 OWF56430.1 - 0.028 14.3 0.4 1.3 8.9 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Poly_export PF02563.16 OWF56430.1 - 0.028 14.6 0.0 1.3 9.3 0.0 2.9 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 OWF56430.1 - 0.041 14.0 0.3 0.58 10.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.14 OWF56430.1 - 0.075 12.7 0.3 0.24 11.0 0.3 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF2267 PF10025.9 OWF56430.1 - 0.089 13.1 0.0 0.28 11.5 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) TetR_C_7 PF14246.6 OWF56430.1 - 0.18 11.8 0.0 11 6.0 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 OWF56430.1 - 0.21 11.7 0.2 0.4 10.8 0.2 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) EF-hand_7 PF13499.6 OWF56431.1 - 5.2e-25 87.7 6.1 1.2e-13 51.3 1.5 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF56431.1 - 4.5e-21 72.8 15.7 2.4e-07 29.8 0.2 5.8 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 OWF56431.1 - 5.9e-20 69.4 9.0 1.7e-06 27.5 0.1 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OWF56431.1 - 1.7e-15 55.7 13.2 2.4e-07 29.9 0.3 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OWF56431.1 - 7.9e-13 48.0 9.8 3.5e-05 23.6 1.3 4.6 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 OWF56431.1 - 1.2e-05 25.1 1.1 0.024 14.6 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56431.1 - 0.00034 20.9 0.3 0.0052 17.1 0.2 2.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OWF56431.1 - 0.035 14.4 0.1 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 OWF56431.1 - 0.19 11.7 3.1 23 4.9 0.2 3.5 2 1 2 4 4 4 0 Caleosin related protein EF-hand_1 PF00036.32 OWF56432.1 - 2.5e-34 114.2 12.0 1e-07 31.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56432.1 - 5.8e-30 103.6 2.2 9.2e-16 58.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56432.1 - 1.2e-28 96.5 5.5 4.5e-08 32.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF56432.1 - 2.7e-28 96.2 6.7 4.2e-08 32.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OWF56432.1 - 4.3e-26 90.5 11.8 3.8e-12 45.9 1.4 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OWF56432.1 - 3.3e-14 53.0 0.2 2.2e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56432.1 - 6.3e-10 38.9 0.8 3.4e-05 23.8 0.3 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56432.1 - 2.6e-08 34.1 0.0 0.00034 20.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OWF56432.1 - 4.4e-08 33.2 7.5 1.3e-05 25.3 2.8 3.1 1 1 3 4 4 4 4 Dockerin type I domain UPF0154 PF03672.13 OWF56432.1 - 0.00016 21.7 0.0 0.049 13.7 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 OWF56432.1 - 0.00026 21.3 0.1 0.37 11.1 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 OWF56432.1 - 0.04 13.8 0.2 11 5.9 0.0 3.1 1 1 2 4 4 4 0 Caleosin related protein Utp21 PF04192.12 OWF56432.1 - 0.098 12.1 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Utp21 specific WD40 associated putative domain Fe_hyd_lg_C PF02906.14 OWF56432.1 - 0.099 12.3 0.2 9 5.9 0.1 2.1 1 1 1 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain DUF1296 PF06972.11 OWF56432.1 - 0.12 12.5 0.2 1 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) OST-HTH PF12872.7 OWF56432.1 - 0.14 12.0 0.0 28 4.6 0.0 2.9 3 0 0 3 3 3 0 OST-HTH/LOTUS domain Excalibur PF05901.11 OWF56432.1 - 5.5 7.7 9.2 3.9 8.2 0.1 3.8 4 0 0 4 4 4 0 Excalibur calcium-binding domain EF-hand_1 PF00036.32 OWF56433.1 - 4.4e-23 79.0 20.4 1.8e-08 33.3 2.4 3.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OWF56433.1 - 1.3e-22 80.0 9.3 3.7e-16 59.3 2.5 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56433.1 - 1e-16 59.4 10.9 3e-07 29.8 0.4 3.8 2 2 2 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF56433.1 - 2.4e-15 56.1 15.4 1.5e-11 43.9 2.0 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF56433.1 - 4.6e-13 48.0 14.0 0.00016 21.0 0.4 3.6 3 1 1 4 4 4 3 EF hand EF-hand_4 PF12763.7 OWF56433.1 - 6.5e-08 32.5 5.0 0.00085 19.2 0.4 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OWF56433.1 - 1.9e-06 28.1 1.4 0.00044 20.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain LXG PF04740.12 OWF56433.1 - 0.00064 19.5 0.2 0.0029 17.3 0.0 2.1 2 1 0 2 2 2 1 LXG domain of WXG superfamily DUF5580 PF17743.1 OWF56433.1 - 0.0014 17.3 0.1 0.0017 17.0 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 OWF56433.1 - 0.0079 16.5 1.3 0.057 13.7 0.2 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Staphylokinase PF02821.16 OWF56433.1 - 0.039 14.4 0.1 0.1 13.0 0.1 1.6 1 1 0 1 1 1 0 Staphylokinase/Streptokinase family Vps23_core PF09454.10 OWF56433.1 - 0.082 12.9 0.1 2.5 8.1 0.0 2.4 2 1 0 2 2 2 0 Vps23 core domain EF-hand_1 PF00036.32 OWF56434.1 - 1e-39 131.1 14.1 9.5e-10 37.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56434.1 - 2.9e-34 117.4 3.8 6.8e-18 64.9 1.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF56434.1 - 1.9e-30 104.5 11.5 3.6e-14 52.4 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF56434.1 - 2.6e-28 95.5 9.5 1.3e-09 37.2 0.1 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OWF56434.1 - 3.6e-22 76.8 9.7 1e-06 27.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56434.1 - 1.4e-16 60.5 0.2 1.2e-08 35.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF56434.1 - 3.7e-09 36.9 0.1 0.00045 20.5 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF56434.1 - 4.9e-09 36.1 1.1 0.0026 17.7 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OWF56434.1 - 1e-06 28.7 0.1 0.0039 17.2 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.11 OWF56434.1 - 0.00023 20.8 4.8 0.00026 20.7 4.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EFhand_Ca_insen PF08726.10 OWF56434.1 - 0.00033 20.7 1.1 0.0016 18.5 0.4 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 OWF56434.1 - 0.00035 20.5 2.6 0.36 10.7 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein EF-hand_11 PF08976.11 OWF56434.1 - 0.00058 20.7 0.0 1.2 10.1 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain RNA_pol_Rpb4 PF03874.16 OWF56434.1 - 0.0011 19.3 0.8 0.79 10.1 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 OWF56434.1 - 0.0013 18.7 1.3 0.39 10.7 0.3 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF5580 PF17743.1 OWF56434.1 - 0.0023 16.6 0.0 0.0023 16.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF4497 PF14924.6 OWF56434.1 - 0.0033 17.9 0.0 1.3 9.5 0.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF4497) DUF3349 PF11829.8 OWF56434.1 - 0.0051 17.5 0.4 6.5 7.6 0.1 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) p25-alpha PF05517.12 OWF56434.1 - 0.014 15.6 1.8 1.6 8.8 0.1 2.6 1 1 1 2 2 2 0 p25-alpha Dockerin_1 PF00404.18 OWF56434.1 - 0.02 15.1 5.1 3.9 7.8 0.9 3.1 1 1 2 3 3 3 0 Dockerin type I domain Poly_export PF02563.16 OWF56434.1 - 0.032 14.5 0.1 1.1 9.5 0.0 2.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein TetR_C_7 PF14246.6 OWF56434.1 - 0.035 14.1 0.1 5.4 7.1 0.0 2.6 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Peptidase_M24 PF00557.24 OWF56434.1 - 0.065 12.9 0.1 0.8 9.3 0.1 2.1 2 1 0 2 2 2 0 Metallopeptidase family M24 EF-hand_14 PF17959.1 OWF56434.1 - 0.082 13.3 0.6 3.8 7.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SapB_1 PF05184.15 OWF56434.1 - 0.083 12.9 1.6 45 4.2 0.0 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 Spore_III_AB PF09548.10 OWF56434.1 - 0.084 13.0 0.5 0.16 12.1 0.4 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF327 PF03885.13 OWF56434.1 - 0.12 12.4 5.5 16 5.5 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF327) Phage_tail_S PF05069.13 OWF56434.1 - 0.15 11.9 0.2 13 5.7 0.0 2.1 1 1 1 2 2 2 0 Phage virion morphogenesis family RuvA_C PF07499.13 OWF56434.1 - 0.16 12.4 0.1 14 6.2 0.1 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain DUF1456 PF07308.13 OWF56434.1 - 0.38 11.1 2.1 4.4 7.7 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) EF-hand_1 PF00036.32 OWF56435.1 - 9.4e-43 140.6 11.9 4.7e-10 38.3 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56435.1 - 1.3e-36 124.9 2.9 6.8e-19 68.1 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF56435.1 - 2e-33 114.0 11.3 1.9e-16 59.7 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF56435.1 - 8.7e-32 106.3 7.4 1.4e-09 37.1 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF56435.1 - 1.2e-27 94.1 8.6 1.2e-06 27.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56435.1 - 2.9e-16 59.5 0.2 2.8e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56435.1 - 7.6e-09 35.5 0.7 0.0013 18.7 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56435.1 - 1.4e-08 35.1 0.1 0.003 17.9 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF56435.1 - 4.5e-06 27.5 0.0 0.004 18.0 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 OWF56435.1 - 8.1e-06 25.8 0.1 0.045 13.8 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.11 OWF56435.1 - 0.00038 20.1 3.9 0.00048 19.8 3.8 1.3 1 1 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 OWF56435.1 - 0.00041 20.3 1.4 0.56 10.1 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.10 OWF56435.1 - 0.0007 19.6 0.9 0.0031 17.6 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 OWF56435.1 - 0.0011 19.6 0.3 1.4 9.7 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 OWF56435.1 - 0.0015 18.9 0.0 1.4 9.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 OWF56435.1 - 0.0018 18.6 0.4 1.3 9.4 0.1 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb4 TerB PF05099.13 OWF56435.1 - 0.0019 18.2 1.0 0.72 9.8 0.1 2.5 1 1 1 2 2 2 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 OWF56435.1 - 0.0033 17.6 5.5 0.28 11.4 0.7 3.0 1 1 1 2 2 2 2 Dockerin type I domain DUF5580 PF17743.1 OWF56435.1 - 0.0034 16.0 0.0 0.0034 16.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) dCache_2 PF08269.11 OWF56435.1 - 0.005 16.1 0.2 0.3 10.2 0.2 2.3 1 1 0 1 1 1 1 Cache domain MotA_activ PF09114.10 OWF56435.1 - 0.0072 16.4 0.4 0.11 12.6 0.1 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain Poly_export PF02563.16 OWF56435.1 - 0.016 15.4 0.1 0.57 10.4 0.0 3.1 2 1 0 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 OWF56435.1 - 0.017 15.0 2.3 0.49 10.2 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 OWF56435.1 - 0.032 14.6 0.2 9.7 6.6 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain Spore_III_AB PF09548.10 OWF56435.1 - 0.046 13.8 1.1 0.15 12.2 0.7 1.8 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Fe_hyd_lg_C PF02906.14 OWF56435.1 - 0.087 12.5 1.0 0.26 10.9 1.0 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 OWF56435.1 - 0.11 12.5 0.0 7.7 6.6 0.0 2.5 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain SapB_1 PF05184.15 OWF56435.1 - 0.3 11.2 5.1 11 6.2 0.1 3.6 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF1641 PF07849.11 OWF56436.1 - 6.7e-08 32.3 0.0 6.3 6.8 0.0 7.4 3 1 7 10 10 10 2 Protein of unknown function (DUF1641) PTP_N PF12453.8 OWF56436.1 - 0.00071 19.2 0.1 4.6e+02 0.7 0.0 7.5 10 0 0 10 10 10 0 Protein tyrosine phosphatase N terminal DUF4833 PF16117.5 OWF56436.1 - 0.0013 18.8 6.9 6 6.9 2.3 4.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4833) CO_deh_flav_C PF03450.17 OWF56436.1 - 0.012 15.8 0.0 34 4.7 0.0 3.7 1 1 5 6 6 6 0 CO dehydrogenase flavoprotein C-terminal domain Nuc_deoxyri_tr2 PF15891.5 OWF56436.1 - 0.012 15.9 0.7 94 3.4 0.1 4.8 1 1 6 7 7 7 0 Nucleoside 2-deoxyribosyltransferase like Slx4 PF09494.10 OWF56436.1 - 0.02 14.9 3.0 66 3.6 1.3 5.2 1 1 1 2 2 2 0 Slx4 endonuclease Dimerisation PF08100.11 OWF56436.1 - 0.038 14.0 6.8 21 5.2 0.1 5.0 2 1 5 7 7 7 0 Dimerisation domain KRE9 PF05390.11 OWF56436.1 - 0.13 13.0 0.0 61 4.4 0.0 3.6 1 1 4 5 5 5 0 Yeast cell wall synthesis protein KRE9/KNH1 Peptidase_M30 PF10460.9 OWF56436.1 - 0.77 8.6 4.4 4.1 6.3 0.5 2.5 1 1 1 2 2 2 0 Peptidase M30 RNA_pol_Rpb4 PF03874.16 OWF56436.1 - 2 8.7 5.7 2e+02 2.3 5.6 2.8 1 1 0 1 1 1 0 RNA polymerase Rpb4 DUF1641 PF07849.11 OWF56437.1 - 1.6e-06 27.8 0.0 4.3 7.3 0.0 5.8 3 1 4 7 7 7 2 Protein of unknown function (DUF1641) SE PF08491.10 OWF56437.1 - 0.003 16.6 4.8 5 6.1 0.1 3.7 1 1 3 4 4 4 2 Squalene epoxidase DUF4833 PF16117.5 OWF56437.1 - 0.0081 16.2 3.9 2.3 8.2 1.5 3.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4833) PTP_N PF12453.8 OWF56437.1 - 0.023 14.4 0.0 3.3e+02 1.1 0.0 5.4 7 0 0 7 7 7 0 Protein tyrosine phosphatase N terminal Nuc_deoxyri_tr2 PF15891.5 OWF56437.1 - 0.027 14.8 0.3 79 3.6 0.0 3.9 1 1 3 4 4 4 0 Nucleoside 2-deoxyribosyltransferase like MrpF_PhaF PF04066.13 OWF56437.1 - 0.04 14.3 2.7 32 5.0 0.1 4.2 1 1 4 5 5 5 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) CO_deh_flav_C PF03450.17 OWF56437.1 - 0.043 14.0 0.0 21 5.4 0.0 3.0 1 1 3 4 4 4 0 CO dehydrogenase flavoprotein C-terminal domain Slx4 PF09494.10 OWF56437.1 - 0.049 13.6 0.9 26 4.9 0.5 4.1 1 1 1 2 2 2 0 Slx4 endonuclease Dimerisation PF08100.11 OWF56437.1 - 0.065 13.3 2.8 15 5.7 0.1 3.8 2 1 2 4 4 4 0 Dimerisation domain KRE9 PF05390.11 OWF56437.1 - 0.17 12.7 0.0 48 4.8 0.0 3.2 1 1 1 3 3 3 0 Yeast cell wall synthesis protein KRE9/KNH1 EF-hand_1 PF00036.32 OWF56438.1 - 2.2e-39 130.1 16.2 4.6e-10 38.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56438.1 - 2e-32 111.4 6.1 1.3e-16 60.8 1.5 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF56438.1 - 7.5e-32 109.0 14.6 3.7e-15 55.5 1.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF56438.1 - 2.9e-28 95.3 10.5 1.1e-09 37.5 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF56438.1 - 2.5e-25 86.8 14.7 9.2e-08 31.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56438.1 - 5.6e-13 49.0 0.1 7.2e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56438.1 - 2e-12 47.0 3.6 2.7e-05 24.1 0.3 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56438.1 - 2.4e-10 40.7 0.4 0.00025 21.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF56438.1 - 2.8e-06 27.2 0.0 0.14 12.2 0.0 2.8 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF56438.1 - 7.3e-06 26.1 4.9 0.01 16.0 0.3 2.9 1 1 2 3 3 3 2 Dockerin type I domain EF-hand_11 PF08976.11 OWF56438.1 - 1.2e-05 26.1 0.1 0.0017 19.2 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain DUF4497 PF14924.6 OWF56438.1 - 0.0014 19.1 0.1 0.73 10.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) DUF3349 PF11829.8 OWF56438.1 - 0.0016 19.1 0.8 4.3 8.2 0.0 2.9 1 1 3 4 4 4 1 Protein of unknown function (DUF3349) EFhand_Ca_insen PF08726.10 OWF56438.1 - 0.0062 16.6 0.4 0.066 13.3 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 OWF56438.1 - 0.0089 16.0 0.6 1.2 9.1 0.0 3.1 1 1 1 3 3 3 1 Caleosin related protein dCache_2 PF08269.11 OWF56438.1 - 0.023 13.9 0.8 4.1 6.5 0.0 2.3 1 1 1 2 2 2 0 Cache domain RNA_pol_Rpb4 PF03874.16 OWF56438.1 - 0.034 14.5 3.2 4.1 7.7 0.4 2.9 2 1 0 2 2 2 0 RNA polymerase Rpb4 SurA_N_3 PF13624.6 OWF56438.1 - 0.051 13.4 1.2 0.17 11.6 0.3 2.0 1 1 1 2 2 2 0 SurA N-terminal domain YqeY PF09424.10 OWF56438.1 - 0.068 13.2 1.1 0.23 11.5 0.5 1.9 1 1 1 2 2 2 0 Yqey-like protein DUF2543 PF10820.8 OWF56438.1 - 0.074 13.2 0.6 7.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) Syntaxin PF00804.25 OWF56438.1 - 0.085 12.5 3.7 0.29 10.8 0.4 2.2 1 1 1 2 2 2 0 Syntaxin DUF1217 PF06748.12 OWF56438.1 - 0.088 12.8 0.4 0.17 11.9 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) Phage_tail_S PF05069.13 OWF56438.1 - 0.11 12.3 0.3 11 5.8 0.0 2.9 1 1 2 3 3 3 0 Phage virion morphogenesis family VCBS PF13517.6 OWF56438.1 - 0.12 13.0 4.0 4.4 8.0 0.1 2.6 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DED PF01335.21 OWF56438.1 - 0.2 12.0 2.5 3.1 8.2 0.1 2.7 3 0 0 3 3 3 0 Death effector domain RloB PF13707.6 OWF56438.1 - 0.25 11.5 3.0 1.7 8.8 0.7 2.1 1 1 1 2 2 2 0 RloB-like protein RAC_head PF16717.5 OWF56438.1 - 0.33 12.0 4.1 17 6.4 0.1 3.3 2 2 2 4 4 4 0 Ribosome-associated complex head domain EF-hand_1 PF00036.32 OWF56439.1 - 5.8e-26 88.1 10.4 1.4e-08 33.7 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56439.1 - 6.7e-26 90.5 3.0 2.6e-13 50.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56439.1 - 1.3e-20 71.5 8.0 1.4e-07 30.9 0.3 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF56439.1 - 5.1e-13 48.6 9.2 4.5e-05 23.2 0.3 3.8 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF56439.1 - 2.3e-12 45.8 5.0 1.1e-05 24.7 0.8 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OWF56439.1 - 2.2e-09 37.5 0.4 0.00024 21.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF56439.1 - 0.00013 22.2 0.3 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 OWF56439.1 - 0.00022 19.9 0.0 0.00022 19.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) UPF0154 PF03672.13 OWF56439.1 - 0.0023 17.9 0.0 0.0091 16.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 OWF56439.1 - 0.0051 16.7 1.6 0.59 10.1 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 OWF56439.1 - 0.016 15.3 0.2 0.04 14.0 0.2 1.7 1 1 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_14 PF17959.1 OWF56439.1 - 0.054 13.8 0.2 1.1 9.6 0.0 2.7 1 1 2 3 3 3 0 EF-hand domain DUF1217 PF06748.12 OWF56439.1 - 0.098 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) EF-hand_1 PF00036.32 OWF56440.1 - 2.9e-34 114.1 8.4 4.4e-08 32.1 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56440.1 - 1.6e-28 98.9 2.2 1.5e-13 50.9 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56440.1 - 3.7e-27 91.9 4.6 3.3e-08 32.8 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF56440.1 - 3.1e-26 91.0 9.6 2.1e-09 37.1 0.6 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF56440.1 - 2.8e-20 70.8 7.1 0.00023 20.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56440.1 - 7e-14 51.9 0.1 6.8e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56440.1 - 1.9e-09 37.4 0.1 0.0022 17.9 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56440.1 - 7.2e-06 26.3 0.0 0.056 13.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OWF56440.1 - 0.00012 22.0 0.1 0.77 9.7 0.0 3.0 2 1 1 3 3 3 2 Caleosin related protein DUF1103 PF06513.11 OWF56440.1 - 0.00091 18.9 1.0 0.0012 18.5 1.0 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) UPF0154 PF03672.13 OWF56440.1 - 0.0018 18.2 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 OWF56440.1 - 0.0028 18.4 0.0 8.1 7.3 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_11 PF08976.11 OWF56440.1 - 0.0041 18.0 0.0 0.033 15.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 OWF56440.1 - 0.0096 16.1 3.2 1.5 9.0 0.6 3.0 1 1 1 2 2 2 1 Dockerin type I domain FGAR-AT_linker PF18072.1 OWF56440.1 - 0.013 16.0 0.4 0.58 10.7 0.0 2.6 2 1 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain MotA_activ PF09114.10 OWF56440.1 - 0.016 15.3 0.1 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Glycos_trans_3N PF02885.17 OWF56440.1 - 0.03 14.2 0.4 36 4.3 0.1 3.8 2 2 1 4 4 4 0 Glycosyl transferase family, helical bundle domain ERAP1_C PF11838.8 OWF56440.1 - 0.031 13.8 0.0 1.3 8.5 0.0 2.0 1 1 1 2 2 2 0 ERAP1-like C-terminal domain TerB PF05099.13 OWF56440.1 - 0.048 13.6 0.2 3.1 7.8 0.1 2.5 1 1 2 3 3 3 0 Tellurite resistance protein TerB EF-hand_14 PF17959.1 OWF56440.1 - 0.063 13.6 0.0 16 5.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain cwf21 PF08312.12 OWF56440.1 - 0.13 12.4 0.5 8.2 6.7 0.1 2.3 2 0 0 2 2 2 0 cwf21 domain DUF1296 PF06972.11 OWF56440.1 - 0.14 12.3 0.3 5.7 7.2 0.2 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1296) TauD PF02668.16 OWF56440.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Excalibur PF05901.11 OWF56440.1 - 0.26 11.9 3.7 1.2e+02 3.4 0.0 4.0 4 0 0 4 4 4 0 Excalibur calcium-binding domain EF-hand_1 PF00036.32 OWF56441.1 - 5.5e-39 128.8 12.7 2.7e-09 35.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56441.1 - 6e-32 109.9 5.1 3.4e-15 56.2 1.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56441.1 - 3.9e-29 98.1 4.5 2.4e-08 33.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF56441.1 - 2.9e-27 94.3 13.2 1.6e-12 47.0 1.7 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF56441.1 - 6.1e-25 85.6 12.4 1.5e-06 27.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56441.1 - 1.7e-14 53.9 0.5 7.2e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56441.1 - 8.9e-09 35.2 2.1 0.004 17.1 0.1 3.0 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56441.1 - 1.3e-07 31.9 0.4 0.0043 17.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF56441.1 - 1.9e-05 25.5 0.0 0.038 14.9 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 OWF56441.1 - 0.00017 21.6 0.0 0.035 14.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF56441.1 - 0.00017 21.7 3.7 0.18 12.1 1.2 2.7 2 1 1 3 3 3 2 Dockerin type I domain TerB PF05099.13 OWF56441.1 - 0.0015 18.5 0.6 0.033 14.2 0.0 2.5 1 1 2 3 3 3 1 Tellurite resistance protein TerB Caleosin PF05042.13 OWF56441.1 - 0.0032 17.4 0.1 0.61 10.0 0.0 2.8 1 1 2 3 3 3 1 Caleosin related protein EF-hand_14 PF17959.1 OWF56441.1 - 0.006 16.9 0.1 0.089 13.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 OWF56441.1 - 0.014 15.7 0.2 2.2 8.6 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 dCache_2 PF08269.11 OWF56441.1 - 0.13 11.4 0.0 6.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Cache domain MotA_activ PF09114.10 OWF56441.1 - 0.16 12.1 0.2 3.8 7.7 0.0 2.3 2 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF5580 PF17743.1 OWF56441.1 - 0.22 10.0 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_1 PF00036.32 OWF56442.1 - 4.5e-34 113.4 17.4 8.3e-10 37.5 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 OWF56442.1 - 1.3e-28 99.2 8.7 1.9e-15 57.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56442.1 - 1.9e-27 92.8 11.2 1.7e-09 36.9 0.2 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OWF56442.1 - 6e-26 90.1 20.0 1.6e-13 50.3 0.8 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF56442.1 - 2.4e-23 80.5 12.0 6.3e-07 28.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56442.1 - 2.2e-08 34.3 0.1 6.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56442.1 - 1.5e-06 28.1 3.6 0.0021 18.0 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OWF56442.1 - 4.8e-06 27.4 0.0 0.015 16.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF56442.1 - 5.2e-06 26.7 0.2 0.066 13.5 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OWF56442.1 - 0.00019 21.4 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 OWF56442.1 - 0.00032 20.8 6.4 0.041 14.1 0.3 3.4 1 1 1 2 2 2 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 OWF56442.1 - 0.00041 20.4 0.2 0.0022 18.0 0.0 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 OWF56442.1 - 0.0059 16.5 0.8 9.9 6.1 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 OWF56442.1 - 0.019 14.9 0.2 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF5580 PF17743.1 OWF56442.1 - 0.02 13.4 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF3349 PF11829.8 OWF56442.1 - 0.025 15.3 0.1 8.2 7.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) DUF3008 PF11450.8 OWF56442.1 - 0.21 11.7 4.0 1.4 9.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) DED PF01335.21 OWF56442.1 - 0.36 11.2 1.6 27 5.2 0.2 2.5 2 1 0 2 2 2 0 Death effector domain EF-hand_1 PF00036.32 OWF56443.1 - 6.2e-41 134.9 12.9 4.8e-10 38.3 0.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56443.1 - 5e-34 116.6 5.5 7.3e-17 61.6 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF56443.1 - 8.8e-31 105.5 12.9 6e-15 54.8 0.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF56443.1 - 6.1e-30 100.6 8.1 1.4e-09 37.1 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF56443.1 - 3.3e-24 83.2 13.4 2.5e-06 26.7 0.2 4.6 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 OWF56443.1 - 4.8e-16 58.8 0.3 1.8e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56443.1 - 6e-09 35.8 1.9 0.00068 19.5 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56443.1 - 7.4e-08 32.7 0.1 0.013 15.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF56443.1 - 7.4e-07 30.0 0.0 0.00025 21.9 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 OWF56443.1 - 3.7e-05 23.7 0.0 0.047 13.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 OWF56443.1 - 0.00017 21.6 1.5 0.65 9.9 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 OWF56443.1 - 0.00049 20.2 3.5 0.083 13.1 1.4 3.0 1 1 2 3 3 3 1 Dockerin type I domain SurA_N_2 PF13623.6 OWF56443.1 - 0.0018 18.1 0.8 0.1 12.5 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain DUF3349 PF11829.8 OWF56443.1 - 0.0022 18.7 0.2 2.5 8.9 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 OWF56443.1 - 0.0028 18.0 0.6 1.9 8.8 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 TerB PF05099.13 OWF56443.1 - 0.0029 17.6 0.5 0.84 9.6 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF5580 PF17743.1 OWF56443.1 - 0.0065 15.1 0.0 0.0068 15.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_3 PF13624.6 OWF56443.1 - 0.013 15.3 0.4 0.22 11.3 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 OWF56443.1 - 0.014 15.7 0.1 4.4 7.7 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain DUF4497 PF14924.6 OWF56443.1 - 0.015 15.7 0.1 5.5 7.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) EFhand_Ca_insen PF08726.10 OWF56443.1 - 0.036 14.1 0.4 0.62 10.2 0.0 2.4 2 2 0 2 2 2 0 Ca2+ insensitive EF hand YqeY PF09424.10 OWF56443.1 - 0.044 13.9 0.5 0.31 11.1 0.3 2.0 1 1 1 2 2 2 0 Yqey-like protein Fe_hyd_lg_C PF02906.14 OWF56443.1 - 0.052 13.2 1.1 0.18 11.5 1.1 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain FGAR-AT_linker PF18072.1 OWF56443.1 - 0.059 13.9 0.0 1.8 9.1 0.0 2.5 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain MotA_activ PF09114.10 OWF56443.1 - 0.084 13.0 0.1 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Phage_TAC_12 PF12363.8 OWF56443.1 - 0.094 13.1 1.1 14 6.2 0.1 2.5 2 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Acetyltransf_11 PF13720.6 OWF56443.1 - 0.14 12.7 0.0 13 6.3 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Spore_III_AB PF09548.10 OWF56443.1 - 0.19 11.8 0.5 0.35 11.0 0.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) EF-hand_1 PF00036.32 OWF56444.1 - 2.7e-34 114.2 26.6 1.6e-10 39.8 0.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56444.1 - 1.4e-27 96.0 15.8 5.7e-14 52.3 6.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56444.1 - 4.7e-25 85.3 18.0 6.1e-09 35.1 0.2 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF56444.1 - 4.8e-25 87.2 23.7 1.7e-15 56.6 4.1 3.8 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF56444.1 - 1.5e-20 71.7 23.5 2.1e-07 30.1 0.7 4.4 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56444.1 - 5.3e-11 42.7 2.6 6.2e-06 26.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56444.1 - 6.6e-08 32.4 11.1 0.00079 19.3 1.2 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56444.1 - 1.9e-06 28.2 3.6 0.0059 16.9 0.7 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OWF56444.1 - 0.00046 21.0 0.3 0.0022 18.8 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 OWF56444.1 - 0.0013 18.5 2.6 0.02 14.7 0.4 2.1 1 1 1 2 2 2 1 SurA N-terminal domain Caleosin PF05042.13 OWF56444.1 - 0.0046 16.9 4.2 2.8 7.9 0.1 3.6 1 1 3 4 4 4 2 Caleosin related protein UPF0154 PF03672.13 OWF56444.1 - 0.0048 16.9 0.1 3.9 7.6 0.0 2.7 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) p25-alpha PF05517.12 OWF56444.1 - 0.0098 16.1 3.9 0.75 10.0 0.2 2.8 1 1 0 2 2 2 1 p25-alpha SurA_N_2 PF13623.6 OWF56444.1 - 0.019 14.8 1.2 0.044 13.7 0.5 2.0 1 1 1 2 2 2 0 SurA N-terminal domain RNA_pol_Rpb4 PF03874.16 OWF56444.1 - 0.036 14.4 1.0 5.6 7.3 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 Na_Ca_ex_C PF16494.5 OWF56444.1 - 0.071 13.6 0.9 0.11 12.9 0.9 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Phage_TAC_12 PF12363.8 OWF56444.1 - 0.36 11.3 4.3 5.6 7.4 0.1 2.6 2 1 1 3 3 3 0 Phage tail assembly chaperone protein, TAC EF-hand_14 PF17959.1 OWF56444.1 - 0.48 10.8 3.6 12 6.3 0.2 2.4 1 1 1 2 2 2 0 EF-hand domain DUF1296 PF06972.11 OWF56444.1 - 0.97 9.6 7.2 0.72 10.0 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1296) Big_3 PF07523.12 OWF56444.1 - 1.2 9.5 3.9 36 4.8 0.1 3.0 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) EF-hand_7 PF13499.6 OWF56445.1 - 8.6e-15 55.0 0.1 3.9e-06 27.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56445.1 - 9.3e-13 47.0 0.1 0.00029 20.5 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OWF56445.1 - 7.6e-10 37.6 0.5 0.0042 16.5 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OWF56445.1 - 5.5e-05 23.4 0.0 0.0088 16.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OWF56445.1 - 0.0016 18.2 4.5 0.9 9.4 0.2 3.9 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OWF56445.1 - 0.077 12.5 1.3 10 5.8 0.0 3.6 3 1 0 3 3 3 0 EF hand EF-hand_1 PF00036.32 OWF56446.1 - 4.9e-21 72.6 0.8 9.8e-07 27.9 0.1 3.8 3 1 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OWF56446.1 - 2.1e-19 69.7 4.8 4.5e-12 46.2 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56446.1 - 1.6e-18 65.0 1.1 4.4e-06 26.2 0.0 3.8 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OWF56446.1 - 5e-11 42.3 5.6 2.9e-05 23.8 0.0 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OWF56446.1 - 5.5e-11 41.4 0.0 0.011 15.2 0.0 3.4 3 0 0 3 3 3 3 EF hand UPF0154 PF03672.13 OWF56446.1 - 8e-05 22.6 0.5 0.27 11.3 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 OWF56446.1 - 0.00025 21.3 0.3 0.21 11.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF56446.1 - 0.013 15.8 0.1 5.5 7.3 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 OWF56446.1 - 0.015 15.6 0.2 2.3 8.6 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain EFhand_Ca_insen PF08726.10 OWF56446.1 - 0.018 15.1 0.4 0.038 14.1 0.1 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand YebG PF07130.12 OWF56446.1 - 0.021 14.6 0.7 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 YebG protein Caleosin PF05042.13 OWF56446.1 - 0.047 13.6 0.0 2.1 8.3 0.0 2.4 2 1 0 2 2 2 0 Caleosin related protein EF-hand_1 PF00036.32 OWF56447.1 - 3.3e-39 129.5 10.1 7.9e-10 37.6 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56447.1 - 1.2e-33 115.3 6.9 1.1e-17 64.2 2.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OWF56447.1 - 8.6e-30 102.4 19.5 1.6e-14 53.4 1.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OWF56447.1 - 9.7e-28 93.7 5.9 4.1e-08 32.5 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OWF56447.1 - 5.4e-24 82.6 8.0 7.8e-05 22.0 0.6 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OWF56447.1 - 2.3e-16 59.9 1.2 9.7e-10 38.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OWF56447.1 - 5.5e-10 39.5 1.6 0.00054 20.2 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OWF56447.1 - 6e-10 39.0 5.7 0.00012 22.0 0.5 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OWF56447.1 - 3.8e-06 27.7 0.1 0.0024 18.7 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 OWF56447.1 - 4.6e-05 23.4 0.8 0.28 11.1 0.0 3.4 1 1 3 4 4 4 2 Caleosin related protein RNA_pol_Rpb4 PF03874.16 OWF56447.1 - 0.00017 21.9 4.5 0.17 12.2 0.2 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 OWF56447.1 - 0.00022 21.3 6.1 0.075 13.2 1.7 2.7 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 OWF56447.1 - 0.00083 18.0 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5580) UPF0154 PF03672.13 OWF56447.1 - 0.0016 18.4 0.4 6.7 6.8 0.0 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) SurA_N_3 PF13624.6 OWF56447.1 - 0.0042 16.9 1.2 0.53 10.1 0.5 2.1 1 1 1 2 2 2 2 SurA N-terminal domain UBA_6 PF18039.1 OWF56447.1 - 0.0044 16.9 0.2 0.47 10.4 0.0 2.4 2 0 0 2 2 2 1 UBA-like domain TerB PF05099.13 OWF56447.1 - 0.0097 15.9 0.9 0.41 10.6 0.2 2.2 1 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 OWF56447.1 - 0.011 16.0 0.6 4.2 7.8 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain Sigma54_CBD PF04963.13 OWF56447.1 - 0.012 15.5 1.2 0.076 12.9 1.1 1.9 1 1 1 2 2 2 0 Sigma-54 factor, core binding domain YqeY PF09424.10 OWF56447.1 - 0.013 15.6 2.5 0.038 14.1 2.4 1.7 1 1 1 2 2 2 0 Yqey-like protein SurA_N_2 PF13623.6 OWF56447.1 - 0.019 14.9 2.8 1.4 8.8 0.5 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF3349 PF11829.8 OWF56447.1 - 0.073 13.8 2.9 4.2 8.2 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF4497 PF14924.6 OWF56447.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) RNase_PH_C PF03725.15 OWF56447.1 - 0.33 11.0 5.6 2.6 8.1 0.3 2.8 2 2 0 2 2 2 0 3' exoribonuclease family, domain 2 PB1 PF00564.24 OWF56447.1 - 1.1 9.3 7.6 17 5.5 0.2 3.5 2 1 1 3 3 3 0 PB1 domain DUF3008 PF11450.8 OWF56447.1 - 4.1 7.6 11.1 3.3 7.9 0.4 3.2 1 1 2 3 3 3 0 Protein of unknwon function (DUF3008) DUF533 PF04391.12 OWF56447.1 - 5.7 6.5 7.8 11 5.6 2.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF533) EF-hand_1 PF00036.32 OWF56448.1 - 4e-34 113.6 16.2 2.8e-08 32.7 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OWF56448.1 - 5.2e-30 103.7 4.5 2.8e-15 56.5 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OWF56448.1 - 1.7e-28 96.1 10.3 1.2e-08 34.2 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OWF56448.1 - 8.1e-21 73.6 11.5 2.1e-08 33.9 0.4 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OWF56448.1 - 2.4e-19 67.9 16.2 2.3e-05 23.7 0.4 4.8 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 OWF56448.1 - 7.4e-13 48.6 0.1 1.7e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OWF56448.1 - 1.1e-05 25.4 3.2 0.48 10.4 0.1 3.0 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OWF56448.1 - 0.00017 21.8 0.2 0.45 10.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 OWF56448.1 - 0.0033 17.5 0.2 0.012 15.6 0.0 2.1 3 0 0 3 3 3 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 OWF56448.1 - 0.0038 18.0 0.8 0.45 11.3 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 OWF56448.1 - 0.0079 16.1 0.4 0.81 9.6 0.0 2.8 1 1 1 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 OWF56448.1 - 0.015 15.5 7.4 0.58 10.4 0.4 2.8 2 2 1 3 3 3 0 Dockerin type I domain DUF2606 PF10794.9 OWF56448.1 - 0.045 13.5 0.1 0.083 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2606) CYYR1 PF10873.8 OWF56449.1 - 0.024 15.1 1.2 0.027 14.9 1.2 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 OWF56449.1 - 1.1 9.3 5.2 1.8 8.7 5.2 1.3 1 0 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 OWF56449.1 - 1.1 9.9 6.0 1.8 9.2 6.0 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage TfoX_N PF04993.13 OWF56450.1 - 0.00044 20.4 3.3 2.7 8.3 1.5 4.0 1 1 1 2 2 2 2 TfoX N-terminal domain DUF1667 PF07892.11 OWF56452.1 - 0.03 14.4 1.0 0.2 11.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1667) UPF0121 PF03661.13 OWF56453.1 - 4.5e-93 311.1 13.2 5.1e-93 310.9 13.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF2101 PF09874.9 OWF56453.1 - 8 6.1 10.0 0.44 10.2 3.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) TatD_DNase PF01026.21 OWF56455.1 - 1.9e-19 70.0 0.0 2.3e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase HLH PF00010.26 OWF56457.1 - 9.4e-18 63.9 0.3 1.4e-17 63.4 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 OWF56457.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Birna_VP4 PF01768.16 OWF56458.1 - 0.049 13.4 3.8 3.1 7.5 0.2 4.2 1 1 5 6 6 6 0 Birnavirus VP4 protein Ribosomal_L28e PF01778.17 OWF56458.1 - 0.51 11.1 15.9 16 6.3 0.1 4.4 1 1 2 4 4 4 0 Ribosomal L28e protein family Sec16_C PF12931.7 OWF56458.1 - 6.2 6.4 11.5 12 5.5 0.5 4.4 1 1 4 6 6 6 0 Sec23-binding domain of Sec16 Mitofilin PF09731.9 OWF56458.1 - 9.1 5.0 10.6 0.47 9.2 4.4 1.7 1 1 0 2 2 2 0 Mitochondrial inner membrane protein BIR PF00653.21 OWF56460.1 - 1e-32 112.6 15.6 1.6e-18 67.1 1.9 3.4 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF56460.1 - 3.2e-13 49.3 7.3 3.2e-13 49.3 7.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF56460.1 - 1.9e-05 24.4 7.7 1.9e-05 24.4 7.7 2.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF56460.1 - 0.016 15.5 9.2 0.016 15.5 9.2 2.9 3 0 0 3 3 3 0 Ring finger domain CNDH2_C PF16858.5 OWF56460.1 - 2.9 7.7 7.3 0.3 10.9 2.8 1.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BIR PF00653.21 OWF56461.1 - 8e-31 106.5 2.8 1e-17 64.6 0.1 3.4 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF56461.1 - 8.9e-11 41.5 14.1 8.9e-11 41.5 14.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF56461.1 - 0.00019 21.2 13.9 0.00019 21.2 13.9 3.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 DUF3725 PF12523.8 OWF56461.1 - 0.079 13.3 0.2 0.079 13.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) zf-RING_2 PF13639.6 OWF56461.1 - 1.5 9.2 18.3 0.7 10.3 14.4 2.6 2 0 0 2 2 2 0 Ring finger domain BIR PF00653.21 OWF56462.1 - 2.7e-31 108.0 9.0 2.3e-19 69.8 2.8 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 OWF56462.1 - 0.017 15.2 0.4 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like BIR PF00653.21 OWF56463.1 - 5.2e-31 107.1 9.5 2.4e-19 69.7 2.8 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 OWF56463.1 - 0.017 15.1 0.6 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like BIR PF00653.21 OWF56464.1 - 6.1e-36 122.9 10.8 1.6e-19 70.3 0.7 3.5 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF56464.1 - 9.2e-14 51.0 6.9 9.2e-14 51.0 6.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF56464.1 - 5.6e-06 26.1 7.7 1.5e-05 24.7 7.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF56464.1 - 0.009 16.3 9.4 0.009 16.3 9.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC PF07967.13 OWF56464.1 - 0.012 15.6 0.1 0.24 11.4 0.0 2.7 2 0 0 2 2 2 0 C3HC zinc finger-like zf-RING_5 PF14634.6 OWF56464.1 - 0.086 12.8 12.3 0.067 13.2 8.0 2.5 2 0 0 2 2 2 0 zinc-RING finger domain BIR PF00653.21 OWF56466.1 - 9e-34 116.0 14.7 1.9e-19 70.1 0.9 3.6 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 OWF56466.1 - 9.7e-14 51.0 7.7 9.7e-14 51.0 7.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OWF56466.1 - 1.1e-05 25.1 6.9 1.1e-05 25.1 6.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OWF56466.1 - 0.016 15.5 9.3 0.016 15.5 9.3 2.6 3 1 0 3 3 3 0 Ring finger domain DNA_RNApol_7kD PF03604.13 OWF56466.1 - 0.062 13.0 2.9 0.98 9.2 0.1 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit EPL1 PF10513.9 OWF56466.1 - 1.4 9.3 10.3 2.1 8.7 3.7 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like BIR PF00653.21 OWF56467.1 - 7.4e-30 103.4 3.9 1e-16 61.4 1.1 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain PyrI_C PF02748.15 OWF56467.1 - 0.023 14.6 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C3HC PF07967.13 OWF56467.1 - 0.16 12.0 0.4 13 5.8 0.2 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like Ank_2 PF12796.7 OWF56468.1 - 8.8e-72 237.7 13.9 3.3e-14 53.2 0.1 6.7 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 OWF56468.1 - 3.8e-46 153.6 8.1 0.0037 17.6 0.0 11.6 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 OWF56468.1 - 6.7e-45 150.6 15.1 1.6e-06 28.2 0.1 10.5 2 1 9 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF56468.1 - 3.7e-40 135.8 11.6 1.1e-05 25.8 0.1 9.4 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56468.1 - 2e-39 129.1 11.1 0.0082 16.6 0.0 11.8 11 0 0 11 11 11 8 Ankyrin repeat HEPN_DZIP3 PF18738.1 OWF56468.1 - 2.9e-28 98.4 0.0 5.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN Prok_Ub PF14454.6 OWF56468.1 - 1.4e-08 34.2 2.9 95 2.8 0.0 9.8 9 1 1 10 10 10 0 Prokaryotic Ubiquitin AAA_24 PF13479.6 OWF56468.1 - 0.00022 21.0 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF4744 PF15918.5 OWF56468.1 - 0.00067 20.5 11.6 91 4.0 0.0 7.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4744) NACHT PF05729.12 OWF56468.1 - 0.0081 16.1 0.2 2.7 7.9 0.0 4.9 3 3 3 7 7 7 1 NACHT domain ABC_tran_CTD PF16326.5 OWF56468.1 - 0.28 11.4 0.8 32 4.8 0.1 2.8 1 1 0 2 2 2 0 ABC transporter C-terminal domain Vinculin PF01044.19 OWF56469.1 - 8.3e-79 266.0 11.3 1.8e-42 145.7 5.0 3.1 3 0 0 3 3 3 3 Vinculin family Reovirus_cap PF00979.17 OWF56469.1 - 0.066 12.4 0.5 0.12 11.5 0.5 1.4 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 I_LWEQ PF01608.17 OWF56469.1 - 0.21 11.8 12.3 5.2 7.3 2.7 4.4 4 2 1 5 5 5 0 I/LWEQ domain CppA_N PF14506.6 OWF56470.1 - 3.6e-11 43.2 3.5 0.67 10.0 0.0 6.0 1 1 4 6 6 6 4 CppA N-terminal DUF480 PF04337.12 OWF56470.1 - 3.4e-06 27.2 85.1 4.3 7.4 4.3 15.4 1 1 16 17 17 17 10 Protein of unknown function, DUF480 Acetyltransf_10 PF13673.7 OWF56470.1 - 0.0016 18.4 6.4 22 5.0 0.0 6.5 1 1 3 7 7 7 1 Acetyltransferase (GNAT) domain DUF3725 PF12523.8 OWF56470.1 - 0.017 15.4 7.5 40 4.6 0.0 7.0 1 1 7 10 10 10 0 Protein of unknown function (DUF3725) HutD PF05962.11 OWF56470.1 - 1.8 8.5 24.0 8.9 6.2 1.5 5.1 1 1 2 3 3 3 0 HutD HOIP-UBA PF16678.5 OWF56472.1 - 8.4e-39 133.0 1.0 2.3e-38 131.6 1.0 1.7 1 0 0 1 1 1 1 HOIP UBA domain pair E3_UbLigase_RBR PF18091.1 OWF56472.1 - 1.6e-27 95.4 0.5 6.6e-27 93.5 0.5 2.2 1 0 0 1 1 1 1 E3 Ubiquitin Ligase RBR C-terminal domain IBR PF01485.21 OWF56472.1 - 1.7e-08 34.5 25.7 2.6e-07 30.7 9.3 5.1 5 0 0 5 5 5 3 IBR domain, a half RING-finger domain PUB PF09409.10 OWF56472.1 - 3.3e-08 33.4 0.2 1.8e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 OWF56472.1 - 0.044 13.7 2.3 26 4.9 0.0 4.2 5 0 0 5 5 5 0 UBA/TS-N domain Focal_AT PF03623.13 OWF56472.1 - 2.1 8.4 6.4 0.79 9.7 0.1 3.2 3 1 0 3 3 3 0 Focal adhesion targeting region Pkinase PF00069.25 OWF56473.1 - 9.1e-66 221.9 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56473.1 - 2.6e-41 141.6 0.0 3.2e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF56473.1 - 1.7e-05 24.3 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OWF56473.1 - 0.1 12.2 0.1 2.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OWF56474.1 - 2.2e-65 220.7 0.0 2.7e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56474.1 - 1.4e-39 135.9 0.0 1.8e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF56474.1 - 0.00048 19.5 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OWF56474.1 - 0.017 14.8 0.2 0.39 10.3 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OWF56475.1 - 7.8e-74 248.4 0.0 9e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56475.1 - 1.9e-43 148.6 0.0 2.3e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OWF56475.1 - 0.0002 20.8 0.0 0.0058 16.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OWF56475.1 - 0.026 14.1 0.2 0.49 10.0 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SPT16 PF08644.11 OWF56476.1 - 7.2e-60 201.5 8.2 2.3e-59 199.9 0.1 3.3 3 1 0 3 3 3 2 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OWF56476.1 - 1.1e-49 168.4 0.5 1.1e-49 168.4 0.5 3.1 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OWF56476.1 - 7.7e-27 94.3 0.0 1.2e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OWF56476.1 - 9e-18 64.5 0.0 3.7e-17 62.5 0.0 2.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Sedlin_N PF04628.13 OWF56477.1 - 1.2e-32 112.8 0.5 1.5e-32 112.5 0.5 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OWF56477.1 - 3.1e-11 43.4 0.3 3.5e-11 43.2 0.3 1.1 1 0 0 1 1 1 1 Sybindin-like family DUF4258 PF14076.6 OWF56478.1 - 0.036 14.4 15.6 1.7e+02 2.6 0.1 9.2 4 4 2 8 8 8 0 Domain of unknown function (DUF4258) MLTD_N PF06474.12 OWF56478.1 - 0.26 11.5 12.5 1.9e+02 2.3 0.0 9.0 12 1 3 15 15 15 0 MltD lipid attachment motif UCH PF00443.29 OWF56479.1 - 0.00013 21.6 4.1 0.0083 15.7 0.5 2.6 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OWF56479.1 - 0.00016 21.4 14.2 0.00025 20.8 3.9 2.5 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Thioredoxin_2 PF13098.6 OWF56479.1 - 0.11 13.0 0.4 0.28 11.6 0.4 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain SDF PF00375.18 OWF56480.1 - 5.3e-85 285.8 30.8 5.9e-85 285.6 30.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Copine PF07002.16 OWF56481.1 - 3.4e-81 271.9 0.0 4.7e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 OWF56481.1 - 3.9e-30 104.2 0.3 1.8e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 OWF56481.1 - 0.0071 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Kelch_1 PF01344.25 OWF56482.1 - 1.2e-41 140.1 9.6 4.6e-09 35.7 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OWF56482.1 - 4.1e-27 93.5 4.8 3.9e-06 26.9 0.0 5.4 3 2 2 5 5 5 5 Kelch motif BTB PF00651.31 OWF56482.1 - 3.9e-25 88.2 0.8 1.7e-23 82.9 0.1 2.8 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 OWF56482.1 - 2.3e-24 85.5 1.1 5.1e-24 84.4 1.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 OWF56482.1 - 6.7e-24 83.6 0.4 7.3e-06 25.9 0.0 5.9 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OWF56482.1 - 4.5e-15 54.9 1.1 0.0022 17.9 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OWF56482.1 - 2.6e-12 46.5 8.5 0.00014 21.8 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OWF56482.1 - 1.1e-09 38.3 0.4 0.92 9.9 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain AAA_lid_9 PF17871.1 OWF56482.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain PIP49_N PF14875.6 OWF56483.1 - 0.0078 16.1 4.8 4.1 7.3 0.1 4.1 1 1 1 4 4 4 4 N-term cysteine-rich ER, FAM69 UPF0179 PF03684.13 OWF56484.1 - 0.06 13.2 10.1 0.19 11.6 0.7 3.7 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0179) PIP49_N PF14875.6 OWF56485.1 - 0.0016 18.4 0.9 1.2 9.0 0.1 2.1 1 1 1 2 2 2 2 N-term cysteine-rich ER, FAM69 zf-RING_14 PF17978.1 OWF56485.1 - 0.21 12.0 8.8 16 6.0 0.1 3.8 1 1 3 4 4 4 0 RING/Ubox like zinc-binding domain CDRN PF05174.12 OWF56485.1 - 0.45 10.3 2.8 7 6.4 0.2 2.3 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus zf-CCHC_6 PF15288.6 OWF56485.1 - 1.2 9.0 14.4 6.5 6.7 0.2 4.0 1 1 3 4 4 4 0 Zinc knuckle zf-C2H2 PF00096.26 OWF56485.1 - 3.5 8.3 12.6 49 4.7 0.2 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type Antistasin PF02822.14 OWF56485.1 - 4.3 8.1 15.4 41 4.9 0.4 4.0 4 0 0 4 4 4 0 Antistasin family PIP49_C PF12260.8 OWF56486.1 - 1.9e-46 158.1 2.6 4.6e-46 156.9 0.0 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 OWF56486.1 - 7.5e-09 35.6 3.5 7.5e-09 35.6 3.5 1.8 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 Myticin-prepro PF10690.9 OWF56486.1 - 0.017 15.4 1.0 0.045 14.0 1.0 1.7 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Carb_anhydrase PF00194.21 OWF56487.1 - 9.4e-47 159.7 0.0 1.1e-46 159.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Methyltr_RsmB-F PF01189.17 OWF56488.1 - 8.5e-38 130.0 0.0 3.4e-37 128.0 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OWF56488.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 OWF56488.1 - 0.022 14.5 0.0 0.065 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain IgGFc_binding PF17517.2 OWF56489.1 - 9.8e-46 156.3 7.7 9.8e-46 156.3 7.7 1.6 2 0 0 2 2 2 1 IgGFc binding protein DUF3284 PF11687.8 OWF56489.1 - 0.023 14.6 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) Big_8 PF17961.1 OWF56489.1 - 0.54 10.4 3.2 0.4 10.8 0.5 2.3 2 1 0 2 2 2 0 Bacterial Ig domain Ank_2 PF12796.7 OWF56490.1 - 3.7e-13 49.9 7.0 0.003 18.1 0.8 5.6 4 2 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OWF56490.1 - 4.4e-08 32.8 3.0 7.6 7.5 0.0 8.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 OWF56490.1 - 5.5e-07 30.0 3.8 0.31 11.7 0.0 6.1 4 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OWF56490.1 - 1.4e-06 28.5 0.1 0.03 14.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OWF56490.1 - 0.00018 21.8 5.9 1.3 9.6 0.0 7.2 7 2 0 7 7 7 1 Ankyrin repeat FH2 PF02181.23 OWF56491.1 - 2.8e-55 188.0 3.2 2.8e-55 188.0 3.2 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Topoisom_I PF01028.20 OWF56492.1 - 2.7e-97 324.6 10.4 6.9e-97 323.2 10.4 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 OWF56492.1 - 8.3e-97 322.8 5.0 8.3e-97 322.8 5.0 3.6 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 OWF56492.1 - 4.3e-34 116.3 1.0 1.7e-33 114.3 1.0 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4407 PF14362.6 OWF56492.1 - 2.4 7.4 6.5 7.8 5.8 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_MCEL PF03291.16 OWF56493.1 - 1.2e-102 343.4 0.0 1.5e-102 343.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OWF56493.1 - 8.5e-13 48.8 0.2 8.4e-12 45.6 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF56493.1 - 3.1e-08 34.1 0.1 1.7e-07 31.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF56493.1 - 2.7e-07 30.5 0.5 4.1e-06 26.7 0.3 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF56493.1 - 5.1e-05 23.2 0.0 9.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF56493.1 - 0.00031 21.4 0.0 0.0012 19.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OWF56493.1 - 0.0077 16.2 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF1279 PF06916.13 OWF56494.1 - 1.9e-24 86.0 0.7 5.2e-24 84.6 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Sedlin_N PF04628.13 OWF56494.1 - 0.077 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Methyltransf_33 PF10017.9 OWF56495.1 - 2.9e-59 200.7 0.0 3.5e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Phospholip_A2_1 PF00068.19 OWF56497.1 - 2.4e-18 66.7 2.3 2.5e-18 66.6 2.3 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 OWF56497.1 - 0.44 10.8 5.7 0.66 10.2 5.7 1.6 1 1 0 1 1 1 0 Phospholipase A2 Glyco_hydro_20 PF00728.22 OWF56498.1 - 2.2e-84 283.9 0.1 2.2e-84 283.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OWF56498.1 - 4.6e-17 63.0 0.0 4.6e-17 63.0 0.0 3.0 3 0 0 3 3 3 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OWF56498.1 - 0.0039 17.9 3.7 0.0057 17.4 0.0 2.8 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 TMEM237 PF15383.6 OWF56498.1 - 9.8 5.2 6.6 21 4.1 6.6 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 Neur_chan_LBD PF02931.23 OWF56501.1 - 4.9e-48 163.4 0.1 6.4e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 OWF56501.1 - 3.5e-15 56.7 6.1 4.8e-15 56.3 6.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 8TM_micro PF17028.5 OWF56501.1 - 0.018 14.8 2.7 0.028 14.1 2.7 1.3 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain HTH_23 PF13384.6 OWF56503.1 - 5.2e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.26 OWF56503.1 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_7 PF02796.15 OWF56503.1 - 0.0015 18.5 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 OWF56503.1 - 0.0059 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 OWF56503.1 - 0.011 15.8 0.7 0.042 14.0 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 OWF56503.1 - 0.02 14.9 1.0 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix HTH_11 PF08279.12 OWF56503.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 OWF56503.1 - 0.049 13.4 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain SAM_1 PF00536.30 OWF56503.1 - 0.089 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GerE PF00196.19 OWF56503.1 - 0.11 12.0 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_30 PF13556.6 OWF56503.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DFRP_C PF16543.5 OWF56504.1 - 5.3e-22 78.1 5.2 5.3e-22 78.1 5.2 3.4 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 OWF56504.1 - 3.1e-06 26.9 1.0 3.1e-06 26.9 1.0 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OWF56504.1 - 8.3e-06 26.5 1.4 8.3e-06 26.5 1.4 3.5 2 1 1 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 OWF56504.1 - 1.4e-05 25.0 6.4 1.4e-05 25.0 6.4 2.8 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 OWF56504.1 - 3.1e-05 23.6 0.7 3.1e-05 23.6 0.7 2.4 3 0 0 3 3 3 1 CCCH-type zinc finger MIP-T3_C PF17749.1 OWF56504.1 - 0.0043 17.0 0.7 0.02 14.9 0.7 2.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Thrombin_light PF09396.10 OWF56504.1 - 0.019 14.7 0.5 0.019 14.7 0.5 2.7 3 0 0 3 3 3 0 Thrombin light chain zf-CCCH_2 PF14608.6 OWF56504.1 - 0.036 14.6 2.4 0.036 14.6 2.4 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OWF56504.1 - 0.15 12.3 5.5 0.72 10.1 0.7 2.8 2 1 0 2 2 2 0 Zinc-finger containing family C1q PF00386.21 OWF56505.1 - 5.1e-19 68.7 0.5 8.8e-19 68.0 0.5 1.4 1 0 0 1 1 1 1 C1q domain FPP PF05911.11 OWF56505.1 - 0.01 14.1 0.2 0.014 13.6 0.2 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4577 PF15145.6 OWF56505.1 - 0.014 15.4 0.8 0.026 14.6 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Guanylate_cyc PF00211.20 OWF56507.1 - 3.8e-65 219.0 0.8 1.3e-64 217.2 0.2 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF56507.1 - 6.5e-36 123.9 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF56507.1 - 4.6e-26 91.7 0.0 8.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 OWF56507.1 - 2e-13 50.2 0.0 6.2e-11 42.0 0.0 2.6 1 1 1 2 2 2 2 Receptor family ligand binding region HNOBA PF07701.14 OWF56507.1 - 0.015 14.8 0.9 0.023 14.1 0.9 1.2 1 0 0 1 1 1 0 Heme NO binding associated Guanylate_cyc PF00211.20 OWF56508.1 - 6.8e-65 218.1 0.4 5.2e-64 215.2 0.1 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 OWF56508.1 - 1.3e-43 149.4 0.0 1.9e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 OWF56508.1 - 1.8e-36 125.8 0.1 3e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF56508.1 - 2.5e-24 86.1 0.0 4.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 OWF56508.1 - 0.0063 16.0 0.3 0.0098 15.3 0.3 1.2 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 OWF56508.1 - 0.15 11.7 0.0 0.36 10.4 0.0 1.6 1 1 0 1 1 1 0 Periplasmic binding protein FA_hydroxylase PF04116.13 OWF56509.1 - 5.4e-24 85.0 12.5 5.4e-24 85.0 12.5 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily 7tm_1 PF00001.21 OWF56510.1 - 3.8e-21 75.6 20.9 4.5e-21 75.4 20.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 OWF56510.1 - 1.3 8.7 23.1 0.18 11.4 9.2 2.3 1 1 0 2 2 2 0 Srg family chemoreceptor SNF PF00209.18 OWF56512.1 - 9.2e-176 585.6 29.0 2.5e-175 584.1 29.0 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family RT_RNaseH_2 PF17919.1 OWF56513.1 - 2.2e-34 117.5 0.1 5.1e-34 116.3 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OWF56513.1 - 2.6e-30 104.8 0.0 5e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OWF56513.1 - 3.2e-18 66.0 0.0 1.2e-17 64.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OWF56513.1 - 5.4e-15 55.3 0.2 5.4e-15 55.3 0.2 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain rve_3 PF13683.6 OWF56513.1 - 0.084 12.7 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Aldo_ket_red PF00248.21 OWF56515.1 - 7.9e-39 133.6 0.0 2.1e-38 132.2 0.0 1.6 1 1 1 2 2 2 1 Aldo/keto reductase family HRDC PF00570.23 OWF56515.1 - 0.16 12.0 0.0 0.57 10.2 0.0 2.0 3 0 0 3 3 3 0 HRDC domain Rad21_Rec8_N PF04825.13 OWF56516.1 - 0.087 13.0 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Pyr_redox_3 PF13738.6 OWF56517.1 - 1.4e-35 123.1 0.0 1.9e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OWF56517.1 - 1.2e-09 37.9 0.0 4.8e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OWF56517.1 - 1.5e-08 34.2 0.0 4.4e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 OWF56517.1 - 2.8e-06 26.0 0.0 5.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 OWF56517.1 - 0.00059 19.5 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OWF56517.1 - 0.0008 18.2 0.1 0.034 12.9 0.0 2.6 2 1 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OWF56517.1 - 0.0013 18.9 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OWF56517.1 - 0.0014 17.9 0.0 0.0029 16.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OWF56517.1 - 0.041 13.1 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OWF56517.1 - 0.15 12.6 0.0 11 6.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 OWF56518.1 - 7.6e-62 207.3 2.9 1.2e-61 206.8 2.9 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OWF56518.1 - 7.2e-37 126.2 0.3 1e-36 125.7 0.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain UPF0444 PF15475.6 OWF56518.1 - 0.65 10.3 5.1 1.6 9.1 0.3 2.7 1 1 1 2 2 2 0 Transmembrane protein C12orf23, UPF0444 RUN PF02759.19 OWF56519.1 - 8.9e-27 93.7 0.3 3.9e-26 91.6 0.0 2.1 2 1 0 2 2 2 1 RUN domain Filament PF00038.21 OWF56519.1 - 0.00093 18.9 23.1 0.00093 18.9 23.1 2.3 1 1 1 2 2 2 1 Intermediate filament protein Trimer_CC PF08954.11 OWF56519.1 - 0.26 10.9 3.9 2.1 8.0 0.1 3.0 2 0 0 2 2 2 0 Trimerisation motif SlyX PF04102.12 OWF56519.1 - 0.35 11.5 23.9 0.57 10.8 3.1 4.0 2 2 1 3 3 3 0 SlyX ATG16 PF08614.11 OWF56519.1 - 0.65 10.2 35.7 0.031 14.5 23.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 OWF56519.1 - 0.69 9.6 25.4 2.3 7.9 6.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) KASH_CCD PF14662.6 OWF56519.1 - 1 9.2 38.6 0.09 12.6 26.0 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ApoO PF09769.9 OWF56519.1 - 3.9 7.4 6.4 0.76 9.8 0.5 2.5 3 0 0 3 3 3 0 Apolipoprotein O 7tm_1 PF00001.21 OWF56520.1 - 2.5e-58 197.5 22.0 3.2e-58 197.1 22.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF56520.1 - 9.6e-12 44.8 19.5 1.3e-11 44.3 19.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 OWF56520.1 - 4.7e-06 26.4 18.8 4.7e-06 26.4 18.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 OWF56520.1 - 0.003 17.3 17.6 0.0077 16.0 17.6 1.6 1 1 0 1 1 1 1 Olfactory receptor Alpha_L_fucos PF01120.17 OWF56521.1 - 9.2e-115 383.8 1.5 1.2e-114 383.4 1.5 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 OWF56521.1 - 1.2e-19 70.7 0.2 2e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 OWF56521.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Claudin_2 PF13903.6 OWF56522.1 - 3e-20 72.8 7.6 4.8e-20 72.1 7.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF56522.1 - 8.2e-06 25.8 12.0 0.0016 18.3 12.0 3.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 OWF56522.1 - 0.0018 17.9 9.0 0.0018 17.9 9.0 2.1 1 1 0 2 2 2 1 SUR7/PalI family Amastin PF07344.11 OWF56522.1 - 0.0036 17.2 4.8 0.0036 17.2 4.8 1.8 2 0 0 2 2 2 1 Amastin surface glycoprotein DUF4064 PF13273.6 OWF56522.1 - 0.66 10.3 10.7 20 5.5 6.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.6 OWF56523.1 - 2e-21 76.6 0.8 2.4e-21 76.4 0.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF56523.1 - 3.9e-13 49.6 1.3 3.1e-11 43.4 1.3 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 OWF56523.1 - 3.1e-05 23.6 4.1 6.6e-05 22.5 4.1 1.6 1 1 0 1 1 1 1 Clc-like Amastin PF07344.11 OWF56523.1 - 4.5e-05 23.3 0.4 8.2e-05 22.5 0.4 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein DuoxA PF10204.9 OWF56523.1 - 0.016 14.3 0.4 0.023 13.7 0.4 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF202 PF02656.15 OWF56523.1 - 0.056 13.9 2.2 0.11 12.9 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ESSS PF10183.9 OWF56523.1 - 0.16 12.2 0.1 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3671 PF12420.8 OWF56523.1 - 0.37 10.9 1.4 6.5 6.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function Ferric_reduct PF01794.19 OWF56523.1 - 0.41 10.8 6.8 0.26 11.4 2.4 2.6 1 1 2 3 3 3 0 Ferric reductase like transmembrane component DUF2569 PF10754.9 OWF56523.1 - 0.48 10.9 6.6 2.9 8.3 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Sugar_transport PF06800.12 OWF56523.1 - 1.3 8.3 4.4 1.9 7.8 0.1 2.5 2 1 0 3 3 3 0 Sugar transport protein DUF4064 PF13273.6 OWF56523.1 - 6.8 7.0 11.7 1.2 9.5 0.5 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF4064) Atthog PF18800.1 OWF56524.1 - 1.6e-67 225.8 8.9 2e-67 225.4 8.9 1.1 1 0 0 1 1 1 1 Attenuator of Hedgehog L_HMGIC_fpl PF10242.9 OWF56524.1 - 7.4e-06 26.3 9.9 1.1e-05 25.7 9.9 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF2975 PF11188.8 OWF56524.1 - 0.0041 17.0 8.0 0.0041 17.0 8.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2975) Claudin_3 PF06653.11 OWF56524.1 - 0.0088 16.0 11.9 0.011 15.7 11.9 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF202 PF02656.15 OWF56524.1 - 0.14 12.6 6.4 0.53 10.8 0.9 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF202) Ank_2 PF12796.7 OWF56525.1 - 2.4e-143 467.1 35.4 6.6e-17 61.9 0.2 12.2 1 1 13 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.30 OWF56525.1 - 1.2e-129 417.6 51.4 1.6e-06 28.3 0.1 23.1 22 1 1 23 23 23 21 Ankyrin repeat Ank_4 PF13637.6 OWF56525.1 - 3.1e-116 378.4 28.0 3.8e-12 46.5 0.0 16.2 5 4 13 19 19 19 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56525.1 - 1.6e-107 338.3 24.0 2.8e-05 24.1 0.0 23.5 23 0 0 23 23 23 21 Ankyrin repeat Ank_5 PF13857.6 OWF56525.1 - 1.9e-105 343.5 31.0 4e-12 46.1 0.0 16.6 3 3 14 19 19 19 17 Ankyrin repeats (many copies) UPA_2 PF17809.1 OWF56525.1 - 2.9e-52 176.0 0.1 1e-51 174.2 0.1 2.1 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 OWF56525.1 - 1.5e-30 105.4 2.1 1.7e-23 82.8 0.0 3.1 3 0 0 3 3 3 2 ZU5 domain Death PF00531.22 OWF56525.1 - 2.9e-16 59.4 1.3 9.7e-16 57.7 0.3 2.5 2 0 0 2 2 2 1 Death domain pPIWI_RE_REase PF18154.1 OWF56525.1 - 0.063 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 REase associating with pPIWI_RE SH2 PF00017.24 OWF56526.1 - 7.4e-16 58.0 0.1 2.2e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 SH2 domain PH PF00169.29 OWF56526.1 - 8.3e-10 39.1 1.4 1.5e-09 38.3 1.4 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OWF56526.1 - 1.3e-05 25.6 1.2 2.5e-05 24.6 1.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Death PF00531.22 OWF56527.1 - 5.9e-13 48.8 0.9 3.9e-12 46.2 0.6 2.2 2 0 0 2 2 2 1 Death domain MAP PF03642.13 OWF56527.1 - 0.08 13.3 0.5 11 6.4 0.1 2.5 2 0 0 2 2 2 0 MAP domain Peptidase_C14 PF00656.22 OWF56528.1 - 9.5e-49 166.6 0.0 1.1e-48 166.3 0.0 1.0 1 0 0 1 1 1 1 Caspase domain NPV_P10 PF05531.12 OWF56529.1 - 0.7 10.4 4.2 6.3 7.3 0.9 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.12 OWF56529.1 - 3.4 7.7 5.2 3.7 7.6 0.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat UBX PF00789.20 OWF56530.1 - 1.2e-10 41.4 0.0 1.4e-05 25.2 0.1 2.6 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.8 OWF56530.1 - 1.5e-08 34.7 0.0 9e-08 32.2 0.1 2.4 3 0 0 3 3 3 1 TUG ubiquitin-like domain 7tm_3 PF00003.22 OWF56531.1 - 6.2e-50 170.1 20.6 1e-49 169.4 20.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OWF56531.1 - 2.9e-25 89.1 0.1 4.5e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region TrbC PF04956.13 OWF56531.1 - 0.062 13.5 3.1 0.15 12.3 1.9 2.2 1 1 1 2 2 2 0 TrbC/VIRB2 family DUF1601 PF07671.11 OWF56533.1 - 0.0017 18.2 1.0 1.5e+02 2.3 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF1601) SHMT PF00464.19 OWF56533.1 - 0.002 16.8 6.3 1.6 7.2 0.1 4.6 1 1 5 6 6 6 2 Serine hydroxymethyltransferase Pox_F15 PF04596.12 OWF56533.1 - 0.014 15.2 0.0 8.1 6.2 0.0 2.9 1 1 2 3 3 3 0 Poxvirus protein F15 Fil_haemagg PF05594.14 OWF56533.1 - 0.026 15.0 0.4 23 5.6 0.0 4.3 2 1 1 3 3 3 0 Haemagluttinin repeat DUF604 PF04646.12 OWF56533.1 - 0.073 12.5 1.7 20 4.5 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function, DUF604 HTH_23 PF13384.6 OWF56533.1 - 0.32 10.8 2.4 1.4e+02 2.4 0.0 4.6 6 0 0 6 6 6 0 Homeodomain-like domain DUF4500 PF14937.6 OWF56533.1 - 0.4 10.7 15.8 46 4.1 0.1 7.0 2 2 5 8 8 8 0 Domain of unknown function (DUF4500) zf-C3HC4_3 PF13920.6 OWF56534.1 - 2.9e-06 27.0 10.4 2.9e-06 27.0 10.4 4.9 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF56534.1 - 0.0016 18.3 11.5 0.0016 18.3 11.5 4.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF56534.1 - 0.0032 17.4 11.4 0.0032 17.4 11.4 5.4 5 1 1 6 6 6 1 zinc-RING finger domain zf-C2H2_4 PF13894.6 OWF56534.1 - 0.058 14.3 1.0 0.058 14.3 1.0 7.9 9 1 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OWF56534.1 - 0.2 11.7 9.5 0.041 13.9 2.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 OWF56534.1 - 0.36 10.7 7.8 20 5.1 0.3 4.5 4 0 0 4 4 4 0 Rad50 zinc hook motif DZR PF12773.7 OWF56534.1 - 1.5 8.9 16.0 0.41 10.7 1.9 4.5 2 1 1 3 3 3 0 Double zinc ribbon MARVEL PF01284.23 OWF56535.1 - 4.5e-24 85.1 5.0 5.4e-24 84.9 5.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ceramidase_alk PF04734.13 OWF56536.1 - 4e-183 609.7 3.8 6.8e-169 562.7 2.0 2.0 1 1 1 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OWF56536.1 - 3.2e-46 157.3 0.1 5.7e-46 156.4 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal 7tm_1 PF00001.21 OWF56537.1 - 5.1e-44 150.6 17.0 6.4e-44 150.3 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OWF56537.1 - 1e-05 25.1 18.0 1.5e-05 24.5 18.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF56537.1 - 0.0015 18.3 17.0 0.0029 17.4 17.0 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 OWF56537.1 - 1.7 8.2 22.4 3.9 7.0 22.4 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx G_glu_transpept PF01019.21 OWF56538.1 - 1.5e-148 495.8 0.0 1.7e-148 495.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Xan_ur_permease PF00860.20 OWF56540.1 - 5.1e-89 298.7 23.0 6.7e-89 298.3 23.0 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 OWF56540.1 - 5.3 7.5 17.3 0.49 10.8 1.7 4.1 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily TGF_beta PF00019.20 OWF56541.1 - 7.2e-15 55.8 2.0 1.8e-14 54.5 0.5 2.5 2 1 0 2 2 2 1 Transforming growth factor beta like domain Cpn60_TCP1 PF00118.24 OWF56542.1 - 1.7e-24 86.3 0.7 1.6e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 TCP-1/cpn60 chaperonin family Glyco_hydro_18 PF00704.28 OWF56543.1 - 2.8e-56 191.5 0.0 3.4e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MBOAT PF03062.19 OWF56544.1 - 2e-45 155.7 27.6 3.6e-45 154.8 27.6 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OWF56544.1 - 0.0016 18.7 3.9 0.0063 16.8 3.9 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family 7kD_DNA_binding PF02294.18 OWF56545.1 - 0.13 12.3 0.3 0.28 11.2 0.3 1.6 1 0 0 1 1 1 0 7kD DNA-binding domain ANF_receptor PF01094.28 OWF56546.1 - 5.2e-84 282.4 0.0 1e-44 153.1 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF56546.1 - 1.5e-19 70.8 0.0 2.6e-10 40.5 0.0 2.5 3 0 0 3 3 3 2 Periplasmic binding protein TMEM154 PF15102.6 OWF56546.1 - 0.0052 16.7 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family PRIMA1 PF16101.5 OWF56546.1 - 0.069 13.2 0.1 0.069 13.2 0.1 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF5527 PF17665.1 OWF56546.1 - 0.29 10.7 1.2 0.75 9.3 1.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Glyco_hydro_31 PF01055.26 OWF56547.1 - 2.9e-39 135.5 0.5 6.7e-27 94.8 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Prothymosin PF03247.14 OWF56547.1 - 0.074 13.5 26.0 0.2 12.1 26.0 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family SDA1 PF05285.12 OWF56547.1 - 0.088 12.2 19.2 0.15 11.5 19.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OWF56547.1 - 0.48 8.6 20.2 0.77 7.9 20.2 1.2 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 OWF56547.1 - 2.3 8.2 30.4 5.9 6.8 30.4 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 OWF56547.1 - 3.1 6.0 14.2 5.3 5.2 14.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OWF56547.1 - 3.8 5.5 21.1 5.6 4.9 21.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Phage_holin_2_3 PF16080.5 OWF56548.1 - 0.064 13.0 10.6 26 4.7 0.0 7.2 2 2 7 9 9 9 0 Bacteriophage holin family HP1 RNase_HII PF01351.18 OWF56548.1 - 0.71 9.7 10.4 0.66 9.8 2.8 2.1 1 1 1 2 2 2 0 Ribonuclease HII 7tm_7 PF08395.12 OWF56549.1 - 0.026 13.8 2.7 0.034 13.4 2.7 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF2207 PF09972.9 OWF56549.1 - 0.19 10.4 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OSTbeta PF15048.6 OWF56549.1 - 0.22 11.6 0.4 0.37 10.9 0.1 1.5 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein NdhL PF10716.9 OWF56549.1 - 1.2 9.1 3.9 0.48 10.4 0.7 1.8 1 1 1 2 2 2 0 NADH dehydrogenase transmembrane subunit LRR_8 PF13855.6 OWF56550.1 - 1.5e-24 85.5 33.5 2.1e-10 40.2 5.0 7.4 5 3 2 7 7 7 5 Leucine rich repeat TIR PF01582.20 OWF56550.1 - 4.6e-19 68.9 0.0 7.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 OWF56550.1 - 1.2e-13 51.7 0.0 3.4e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_4 PF12799.7 OWF56550.1 - 3.9e-12 46.2 43.4 0.0075 16.7 2.9 10.2 6 3 2 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OWF56550.1 - 0.00069 19.8 32.2 3.5 8.5 0.8 10.3 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_9 PF14580.6 OWF56550.1 - 0.0026 17.3 11.2 1.8 8.0 1.6 3.8 3 1 1 4 4 4 3 Leucine-rich repeat HOK_GEF PF01848.16 OWF56550.1 - 0.19 11.2 0.6 0.43 10.0 0.6 1.6 1 0 0 1 1 1 0 Hok/gef family LRR_6 PF13516.6 OWF56550.1 - 1.6 8.9 46.6 0.13 12.4 0.5 10.3 11 0 0 11 11 11 0 Leucine Rich repeat OAD_gamma PF04277.13 OWF56551.1 - 0.00094 19.7 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Tmemb_9 PF05434.11 OWF56551.1 - 0.0075 16.2 0.4 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 TMEM9 Shisa PF13908.6 OWF56551.1 - 0.012 15.9 2.5 0.019 15.2 2.5 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OWF56551.1 - 0.033 14.1 1.6 0.054 13.4 1.6 1.3 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 OWF56551.1 - 0.04 13.5 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 OWF56551.1 - 0.079 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TCR_zetazeta PF11628.8 OWF56551.1 - 0.2 11.4 0.3 0.2 11.4 0.3 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain RRM_1 PF00076.22 OWF56553.1 - 1.1e-08 34.8 0.6 3.1e-08 33.3 0.6 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OWF56553.1 - 1.3e-05 25.3 0.1 0.00034 20.7 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif CENP-P PF13096.6 OWF56554.1 - 3.8e-23 82.1 0.4 5.8e-23 81.5 0.4 1.3 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DMAP1 PF05499.12 OWF56554.1 - 0.0052 16.7 0.8 0.013 15.3 0.8 1.7 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Fib_alpha PF08702.10 OWF56554.1 - 0.029 14.6 0.3 0.075 13.2 0.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OWF56554.1 - 0.14 12.1 0.7 0.71 9.9 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Q_salvage PF10343.9 OWF56555.1 - 6e-116 387.0 2.6 7.2e-116 386.7 2.6 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 OWF56555.1 - 0.028 13.1 0.0 1 8.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1688) Peptidase_M4_C PF02868.15 OWF56555.1 - 0.084 12.7 0.2 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Ank_2 PF12796.7 OWF56556.1 - 3.6e-31 107.6 2.9 6.7e-12 45.8 0.3 3.2 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF56556.1 - 1.3e-17 63.9 0.7 1.6e-07 31.7 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56556.1 - 5.7e-17 60.1 0.3 0.0062 17.0 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OWF56556.1 - 1.3e-14 54.1 0.4 4.6e-05 23.6 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OWF56556.1 - 5.7e-12 45.5 0.4 0.047 14.2 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat SOCS_box PF07525.16 OWF56556.1 - 1.1e-06 28.8 1.6 2.1e-06 28.0 1.6 1.5 1 0 0 1 1 1 1 SOCS box HicA_toxin PF07927.12 OWF56556.1 - 0.039 14.0 0.0 4.8 7.3 0.0 3.3 3 0 0 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, EphA2_TM PF14575.6 OWF56557.1 - 0.0028 18.5 0.0 0.0091 16.9 0.0 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OWF56557.1 - 0.014 15.3 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF5385 PF17359.2 OWF56557.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Orthoreo_P10 PF07204.11 OWF56557.1 - 0.065 13.2 0.5 0.36 10.8 0.0 2.3 2 1 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Syndecan PF01034.20 OWF56557.1 - 0.088 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM51 PF15345.6 OWF56557.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Methyltransf_31 PF13847.6 OWF56559.1 - 1.2e-23 83.6 0.0 1.4e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF56559.1 - 1.5e-18 67.4 0.0 2.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF56559.1 - 1.6e-18 67.1 0.0 2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF56559.1 - 1.7e-15 57.5 0.0 3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF56559.1 - 2.3e-15 57.1 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OWF56559.1 - 2.5e-09 36.9 0.1 4.1e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OWF56559.1 - 6e-09 35.8 0.0 7.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 OWF56559.1 - 7.9e-09 35.2 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OWF56559.1 - 5.3e-06 25.9 0.0 7.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 OWF56559.1 - 2.4e-05 23.6 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 OWF56559.1 - 2.5e-05 23.9 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 OWF56559.1 - 3.4e-05 23.4 0.1 4.4e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 OWF56559.1 - 0.00031 19.8 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 OWF56559.1 - 0.0018 18.0 0.3 0.0046 16.7 0.3 1.6 1 1 0 1 1 1 1 Lysine methyltransferase CheR PF01739.18 OWF56559.1 - 0.0021 17.6 0.1 0.013 15.0 0.0 2.2 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 OWF56559.1 - 0.0025 17.6 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 OWF56559.1 - 0.0039 16.7 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 OWF56559.1 - 0.0048 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OWF56559.1 - 0.006 16.7 0.0 0.0099 16.0 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OWF56559.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DAHP_synth_1 PF00793.20 OWF56559.1 - 0.024 13.5 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 DAHP synthetase I family Methyltransf_24 PF13578.6 OWF56559.1 - 0.044 14.8 0.0 0.085 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 OWF56559.1 - 0.07 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_PK PF05891.12 OWF56559.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 OWF56559.1 - 0.09 12.1 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 OWF56559.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 OWF56559.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) G2BR PF18442.1 OWF56560.1 - 0.16 11.6 32.9 5.6 6.7 0.5 8.8 9 0 0 9 9 9 0 E3 gp78 Ube2g2-binding region (G2BR) IES5 PF17335.2 OWF56561.1 - 2.2 8.6 44.1 2.4 8.5 2.1 7.0 1 1 5 7 7 7 0 Ino80 complex subunit 5 Dicistro_VP4 PF11492.8 OWF56561.1 - 6 6.9 9.6 12 5.9 0.3 4.3 3 2 2 5 5 5 0 Cricket paralysis virus, VP4 VCX_VCY PF15231.6 OWF56563.1 - 5.3e-12 46.6 0.0 1.5 9.5 0.0 6.1 1 1 6 7 7 7 6 Variable charge X/Y family 7tm_1 PF00001.21 OWF56564.1 - 2.4e-20 73.0 23.6 3.2e-20 72.6 23.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF56564.1 - 2.7 7.6 30.0 0.65 9.6 25.0 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx OTT_1508_deam PF14441.6 OWF56565.1 - 3.3e-07 30.2 28.3 7.4 6.7 0.1 16.0 6 4 2 8 8 8 2 OTT_1508-like deaminase BAMBI PF06211.12 OWF56565.1 - 0.0032 17.7 5.6 0.73 10.1 0.1 6.0 4 3 2 6 6 6 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain DUF1651 PF07864.11 OWF56565.1 - 0.011 16.1 22.2 42 4.6 0.1 11.4 5 4 9 16 16 16 0 Protein of unknown function (DUF1651) Glypican PF01153.19 OWF56565.1 - 0.4 9.4 1.8 8.6 5.1 0.1 2.2 2 0 0 2 2 2 0 Glypican EF-hand_7 PF13499.6 OWF56566.1 - 2.3e-18 66.4 3.0 1.1e-09 38.6 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OWF56566.1 - 8.3e-17 59.4 5.6 1.3e-05 24.4 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OWF56566.1 - 2e-16 58.4 1.3 4.8e-06 26.1 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OWF56566.1 - 1.2e-11 43.5 4.1 0.00014 21.2 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OWF56566.1 - 4.5e-08 32.8 7.2 0.0015 18.4 0.3 4.1 2 1 2 4 4 4 3 EF-hand domain pair PMBR PF09373.10 OWF56566.1 - 0.00016 21.7 0.7 5.9 7.2 0.1 4.1 4 0 0 4 4 4 1 Pseudomurein-binding repeat DUF5580 PF17743.1 OWF56566.1 - 0.022 13.3 0.0 3.4 6.1 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 OWF56566.1 - 0.022 14.6 0.5 3 7.8 0.0 2.8 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 OWF56566.1 - 0.027 14.8 0.1 3.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_2 PF13623.6 OWF56566.1 - 0.029 14.2 0.1 3 7.7 0.0 2.8 2 1 1 3 3 3 0 SurA N-terminal domain Arylesterase PF01731.20 OWF56567.1 - 1.1e-12 48.0 0.5 3e-12 46.6 0.2 2.0 2 0 0 2 2 2 1 Arylesterase SGL PF08450.12 OWF56567.1 - 2.8e-08 33.7 0.0 1.3e-07 31.4 0.0 1.9 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 OWF56567.1 - 0.0072 15.6 0.0 0.02 14.1 0.0 1.7 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller TNFR_c6 PF00020.18 OWF56568.1 - 3.2e-16 59.4 33.0 1.9e-05 25.0 7.7 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region TMEM154 PF15102.6 OWF56568.1 - 0.056 13.3 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 OWF56568.1 - 0.73 9.8 3.3 1 9.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) tRNA_anti-codon PF01336.25 OWF56569.1 - 0.00064 19.7 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 OWF56569.1 - 0.0007 19.4 0.0 0.00083 19.1 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 DUF4082 PF13313.6 OWF56569.1 - 0.073 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Lectin_C PF00059.21 OWF56570.1 - 4.6e-08 33.8 0.3 9.4e-05 23.1 0.2 3.0 2 1 0 2 2 2 2 Lectin C-type domain Chordopox_A33R PF05966.12 OWF56570.1 - 0.17 11.1 0.0 0.67 9.2 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A33R protein DUF4113 PF13438.6 OWF56571.1 - 0.021 14.9 0.0 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) CinA PF02464.17 OWF56571.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Competence-damaged protein DUF4203 PF13886.6 OWF56571.1 - 0.64 9.7 8.3 0.4 10.3 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) 7tm_2 PF00002.24 OWF56572.1 - 1.7e-39 135.6 22.8 2.2e-39 135.2 22.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 OWF56572.1 - 1.3e-15 57.6 1.8 2.5e-15 56.7 1.8 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Baculo_11_kDa PF06143.11 OWF56572.1 - 0.0057 16.2 0.2 0.0057 16.2 0.2 3.4 4 0 0 4 4 4 1 Baculovirus 11 kDa family POPLD PF08170.12 OWF56573.1 - 0.0063 16.8 10.4 12 6.4 0.1 5.1 1 1 3 4 4 4 3 POPLD (NUC188) domain DUF4744 PF15918.5 OWF56574.1 - 1.3e-53 179.8 189.0 0.0011 19.7 7.5 15.5 1 1 30 31 31 31 31 Domain of unknown function (DUF4744) Laminin_II PF06009.12 OWF56574.1 - 9.4e-49 165.0 23.9 0.0002 21.4 0.1 11.4 1 1 11 13 13 13 13 Laminin Domain II DUF16 PF01519.16 OWF56574.1 - 4.3e-39 133.2 0.0 0.016 15.7 0.0 14.4 1 1 6 7 7 7 7 Protein of unknown function DUF16 IFT57 PF10498.9 OWF56574.1 - 2.7e-34 118.7 94.5 0.0013 17.8 6.6 10.6 1 1 9 10 10 10 10 Intra-flagellar transport protein 57 DUF948 PF06103.11 OWF56574.1 - 1.9e-33 114.6 25.5 0.11 12.8 0.2 13.2 1 1 1 2 2 1 1 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 OWF56574.1 - 2.9e-29 101.9 72.8 0.025 14.5 1.0 11.7 1 1 11 12 12 12 11 Sec34-like family DUF5344 PF17279.2 OWF56574.1 - 1.1e-22 80.4 81.8 13 6.4 1.2 23.9 1 1 15 16 16 16 0 Family of unknown function (DUF5344) LXG PF04740.12 OWF56574.1 - 2.1e-21 76.6 97.6 0.026 14.3 3.0 12.1 1 1 14 15 15 15 15 LXG domain of WXG superfamily COG6 PF06419.11 OWF56574.1 - 1.2e-18 66.7 24.5 0.56 8.4 0.1 10.6 1 1 6 8 8 8 7 Conserved oligomeric complex COG6 EzrA PF06160.12 OWF56574.1 - 2e-18 65.9 115.1 0.0051 15.1 17.1 7.3 1 1 7 8 8 8 8 Septation ring formation regulator, EzrA Arfaptin PF06456.13 OWF56574.1 - 2.5e-18 66.5 48.1 0.35 10.4 1.0 12.0 1 1 13 14 14 14 13 Arfaptin-like domain PMC2NT PF08066.12 OWF56574.1 - 3.1e-18 66.2 31.7 22 5.8 0.1 13.0 1 1 1 2 2 1 0 PMC2NT (NUC016) domain DUF3450 PF11932.8 OWF56574.1 - 3.5e-18 65.8 11.4 0.49 9.6 0.1 7.7 1 1 5 8 8 8 8 Protein of unknown function (DUF3450) MCPsignal PF00015.21 OWF56574.1 - 5.1e-18 65.5 54.8 1.8e+04 -35.3 54.8 9.5 1 1 0 1 1 0 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 OWF56574.1 - 5.2e-18 65.3 25.9 0.45 10.6 0.4 9.1 1 1 10 11 11 11 11 Protein of unknown function (DUF1664) FH2 PF02181.23 OWF56574.1 - 4.9e-17 62.1 46.1 0.0082 15.3 1.4 9.2 1 1 7 8 8 8 8 Formin Homology 2 Domain BLOC1_2 PF10046.9 OWF56574.1 - 1.6e-15 57.1 80.9 0.29 11.4 2.3 11.6 1 1 9 12 12 12 12 Biogenesis of lysosome-related organelles complex-1 subunit 2 YkyA PF10368.9 OWF56574.1 - 5.5e-14 52.3 124.1 0.025 14.2 16.9 7.8 1 1 3 4 4 2 2 Putative cell-wall binding lipoprotein DUF745 PF05335.13 OWF56574.1 - 6.3e-14 52.1 3.9 1.2 8.9 0.2 7.7 1 1 7 8 8 8 3 Protein of unknown function (DUF745) TMPIT PF07851.13 OWF56574.1 - 1.5e-11 44.2 62.7 0.34 10.1 2.1 8.9 1 1 8 9 9 9 8 TMPIT-like protein LOH1CR12 PF10158.9 OWF56574.1 - 4.4e-11 42.9 44.3 5.5 7.0 0.6 11.4 1 1 10 12 12 12 0 Tumour suppressor protein Lge1 PF11488.8 OWF56574.1 - 1.8e-10 40.8 45.8 53 4.1 0.1 16.0 1 1 3 4 4 3 0 Transcriptional regulatory protein LGE1 HAUS4 PF14735.6 OWF56574.1 - 6.7e-10 39.1 78.0 12 5.5 0.8 19.1 1 1 26 27 27 27 0 HAUS augmin-like complex subunit 4 zf-H2C2 PF09337.10 OWF56574.1 - 7.4e-10 38.9 105.0 85 3.5 0.0 33.9 1 1 49 50 50 50 0 H2C2 zinc finger DUF730 PF05325.11 OWF56574.1 - 2.7e-09 37.1 32.1 27 4.8 0.4 13.7 1 1 8 10 10 10 0 Protein of unknown function (DUF730) Transcrip_act PF04949.13 OWF56574.1 - 3.1e-08 33.6 12.5 39 4.1 0.0 10.7 1 1 9 10 10 10 0 Transcriptional activator Jnk-SapK_ap_N PF09744.9 OWF56574.1 - 3.9e-07 30.4 21.2 2.7 8.2 0.2 7.2 1 1 1 2 2 1 1 JNK_SAPK-associated protein-1 DUF812 PF05667.11 OWF56574.1 - 7.6e-07 28.4 25.7 3e+02 0.0 25.7 4.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Syntaxin PF00804.25 OWF56574.1 - 1.2e-06 28.3 31.4 2.4 7.8 0.8 7.1 1 1 4 5 5 5 3 Syntaxin THOC7 PF05615.13 OWF56574.1 - 5.4e-05 23.5 22.3 1.8e+02 2.4 0.2 6.5 1 1 1 2 2 1 0 Tho complex subunit 7 ATG16 PF08614.11 OWF56574.1 - 0.00018 21.8 13.1 3.7e+03 -2.1 13.1 5.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 OWF56574.1 - 0.00096 18.8 79.0 33 4.0 1.1 15.2 1 1 7 8 8 8 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TelA PF05816.11 OWF56574.1 - 0.0053 15.9 48.5 0.43 9.6 1.4 8.0 1 1 8 9 9 9 1 Toxic anion resistance protein (TelA) V_ATPase_I PF01496.19 OWF56574.1 - 0.012 13.5 62.9 1.8e+04 -27.2 62.8 6.4 1 1 0 1 1 0 0 V-type ATPase 116kDa subunit family Myosin_tail_1 PF01576.19 OWF56574.1 - 0.013 13.4 0.1 8.7 4.0 0.0 2.9 1 1 2 3 3 3 0 Myosin tail DASH_Duo1 PF08651.10 OWF56574.1 - 0.023 14.5 55.6 66 3.4 0.5 15.3 1 1 10 11 11 10 0 DASH complex subunit Duo1 APG17 PF04108.12 OWF56574.1 - 0.14 11.3 104.8 4.3 6.3 8.6 7.8 1 1 4 5 5 3 0 Autophagy protein Apg17 Phage_Gp23 PF10669.9 OWF56574.1 - 0.77 10.1 19.7 2.9e+02 1.8 0.1 8.9 1 1 11 13 13 13 0 Protein gp23 (Bacteriophage A118) Sec8_exocyst PF04048.14 OWF56574.1 - 2.6 7.9 120.1 8.9 6.2 4.8 11.1 1 1 8 10 10 10 0 Sec8 exocyst complex component specific domain DUF4795 PF16043.5 OWF56574.1 - 3.2 7.3 30.5 97 2.5 1.0 9.5 1 1 1 2 2 1 0 Domain of unknown function (DUF4795) TryThrA_C PF12319.8 OWF56578.1 - 0.0051 16.3 8.3 94 2.4 0.0 7.1 2 1 5 9 9 9 3 Tryptophan-Threonine-rich plasmodium antigen C terminal Homeodomain PF00046.29 OWF56579.1 - 4.6e-24 84.0 5.8 4.6e-24 84.0 5.8 2.1 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 OWF56579.1 - 1.7e-06 27.6 0.1 3.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 OWF56579.1 - 0.025 14.5 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain QVR PF17064.5 OWF56580.1 - 4.8e-07 29.9 5.3 8.3e-07 29.2 5.3 1.4 1 1 0 1 1 1 1 Sleepless protein Activin_recp PF01064.23 OWF56580.1 - 0.055 14.6 5.1 0.12 13.4 5.1 1.6 1 1 0 1 1 1 0 Activin types I and II receptor domain WAC_Acf1_DNA_bd PF10537.9 OWF56581.1 - 4.2e-22 78.6 0.5 4.2e-22 78.6 0.5 3.0 3 0 0 3 3 2 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 OWF56581.1 - 2.5e-21 75.3 19.8 4.7e-12 45.6 6.2 2.8 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 OWF56581.1 - 3.6e-21 75.0 0.1 1.1e-20 73.5 0.1 1.9 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 OWF56581.1 - 1.4e-20 73.6 0.1 1.4e-20 73.6 0.1 6.0 7 1 0 7 7 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 OWF56581.1 - 7.9e-05 22.1 6.9 0.066 12.8 1.0 2.9 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 OWF56581.1 - 0.00027 21.1 7.2 0.0087 16.3 1.8 3.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain WHIM1 PF15612.6 OWF56581.1 - 0.0017 17.8 0.2 0.0041 16.6 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Prok-RING_1 PF14446.6 OWF56581.1 - 0.0028 17.5 16.5 0.01 15.8 1.5 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 OWF56581.1 - 0.023 14.9 7.9 1.7 8.9 1.7 3.3 2 0 0 2 2 2 0 PHD-zinc-finger like domain DDT PF02791.17 OWF56581.1 - 0.032 14.6 0.1 0.088 13.1 0.1 1.8 1 0 0 1 1 1 0 DDT domain C1_2 PF03107.16 OWF56581.1 - 0.5 10.7 10.9 0.028 14.7 1.2 3.0 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 OWF56581.1 - 3.2 7.7 16.5 0.24 11.3 1.8 2.9 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ANAPC11 PF12861.7 OWF56581.1 - 4.8 7.3 8.2 0.62 10.2 0.4 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger XPG_I PF00867.18 OWF56582.1 - 1.6e-23 82.9 0.0 6.7e-23 80.9 0.0 2.2 1 0 0 1 1 1 1 XPG I-region Chromo_2 PF18704.1 OWF56582.1 - 9.2e-20 70.7 0.4 2.8e-19 69.1 0.4 1.9 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 XPG_N PF00752.17 OWF56582.1 - 8.1e-13 48.7 0.0 2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain I-set PF07679.16 OWF56584.1 - 0 1065.9 31.1 1.5e-19 69.8 0.0 25.6 26 0 0 26 26 25 23 Immunoglobulin I-set domain fn3 PF00041.21 OWF56584.1 - 6.7e-229 741.0 19.1 5e-17 62.0 0.0 16.9 16 0 0 16 16 15 15 Fibronectin type III domain Ig_3 PF13927.6 OWF56584.1 - 2.4e-204 662.5 22.5 2.9e-12 47.0 0.0 25.1 26 0 0 26 26 23 22 Immunoglobulin domain ig PF00047.25 OWF56584.1 - 2.8e-109 357.5 22.6 7.4e-08 32.5 0.0 22.3 22 0 0 22 22 22 17 Immunoglobulin domain Ig_2 PF13895.6 OWF56584.1 - 1.2e-104 342.8 17.0 2e-09 37.7 0.0 22.0 22 0 0 22 22 22 17 Immunoglobulin domain Pkinase PF00069.25 OWF56584.1 - 1.8e-67 227.5 0.0 3.3e-67 226.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 OWF56584.1 - 1e-34 119.0 36.5 0.063 13.5 0.2 24.7 22 8 0 22 22 21 7 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 OWF56584.1 - 3.8e-33 114.9 0.0 6.7e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 OWF56584.1 - 2e-26 91.9 8.7 0.098 12.7 0.0 15.3 15 0 0 15 15 14 6 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 OWF56584.1 - 9.2e-19 67.8 25.2 0.29 11.7 0.0 15.8 17 1 0 17 17 13 3 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 OWF56584.1 - 9.3e-18 64.0 0.1 0.23 11.3 0.0 12.3 13 0 0 13 13 13 1 Tissue factor Izumo-Ig PF16706.5 OWF56584.1 - 7.4e-14 51.6 11.1 3.8 7.6 0.1 14.0 15 0 0 15 15 14 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 OWF56584.1 - 2.3e-13 50.3 8.6 0.32 11.2 0.0 12.5 13 0 0 13 13 12 2 Natural killer cell receptor 2B4 BiPBP_C PF06832.12 OWF56584.1 - 6.3e-11 42.2 0.0 0.98 9.5 0.0 9.1 9 0 0 9 9 7 1 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 OWF56584.1 - 2.4e-08 34.3 18.1 0.67 10.4 0.1 12.2 14 0 0 14 14 13 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 OWF56584.1 - 1.6e-07 30.7 0.1 4.5 6.9 0.0 7.2 9 0 0 9 9 6 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 OWF56584.1 - 8.2e-06 25.8 0.0 0.1 12.6 0.0 6.7 9 0 0 9 9 6 1 C17orf99 Ig domain DUF11 PF01345.18 OWF56584.1 - 0.00015 22.0 11.1 0.22 11.8 0.0 7.9 9 1 0 9 9 7 1 Domain of unknown function DUF11 DUF2369 PF10179.9 OWF56584.1 - 0.00099 19.4 0.0 2.3e+02 2.2 0.0 7.8 9 0 0 9 9 9 0 Uncharacterised conserved protein (DUF2369) Kdo PF06293.14 OWF56584.1 - 0.0036 16.7 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ig_4 PF16680.5 OWF56584.1 - 0.008 16.4 28.2 7.1 7.0 0.0 11.8 11 2 0 11 11 11 0 T-cell surface glycoprotein CD3 delta chain Ig_GlcNase PF18368.1 OWF56584.1 - 0.032 14.4 0.3 1.4e+02 2.6 0.0 5.2 5 0 0 5 5 5 0 Exo-beta-D-glucosaminidase Ig-fold domain CBM_48 PF02922.18 OWF56584.1 - 0.045 14.1 1.7 44 4.5 0.0 6.9 9 0 0 9 9 4 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) APH PF01636.23 OWF56584.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CDC48_2 PF02933.17 OWF56584.1 - 0.076 12.8 1.0 5.4 6.9 0.0 4.4 5 0 0 5 5 4 0 Cell division protein 48 (CDC48), domain 2 V-set_CD47 PF08204.11 OWF56584.1 - 0.81 9.7 10.9 13 5.7 0.0 6.1 6 0 0 6 6 6 0 CD47 immunoglobulin-like domain ADAM_CR_2 PF17771.1 OWF56585.1 - 2.6e-18 66.3 5.9 2.6e-18 66.3 5.9 3.7 2 1 2 4 4 4 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 OWF56585.1 - 1.4e-12 48.2 0.0 3.7e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin PF01421.19 OWF56585.1 - 2.1e-12 47.4 0.0 1.4e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 OWF56585.1 - 5.5e-08 33.4 0.2 1.7e-07 31.8 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OWF56585.1 - 4.3e-07 30.0 0.3 9.6e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF56585.1 - 6.8e-07 29.1 0.1 1.3e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Zn-C2H2_12 PF18112.1 OWF56588.1 - 0.01 16.3 1.0 0.023 15.2 1.0 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 OWF56588.1 - 5.4 8.1 5.3 1.1 10.2 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Patatin PF01734.22 OWF56590.1 - 4.5e-14 53.1 0.2 6.9e-13 49.2 0.3 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase RNase_H2_suC PF08615.11 OWF56591.1 - 1.7e-09 38.0 5.6 1.9 8.7 0.1 6.6 4 3 3 7 7 7 4 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Herpes_U34 PF04541.13 OWF56591.1 - 0.056 12.7 0.9 22 4.2 0.1 3.1 2 1 1 3 3 3 0 Herpesvirus virion protein U34 UPF0715 PF17094.5 OWF56591.1 - 0.13 12.9 1.8 63 4.2 0.0 4.0 3 3 1 4 4 4 0 Uncharacterised protein family (UPF0715) SPASM PF13186.6 OWF56591.1 - 1.6 9.3 7.7 23 5.6 0.3 3.9 2 1 1 3 3 3 0 Iron-sulfur cluster-binding domain Toxin_7 PF05980.12 OWF56591.1 - 2 8.7 14.2 34 4.8 0.0 5.7 6 0 0 6 6 6 0 Toxin 7 HSP20 PF00011.21 OWF56592.1 - 5e-18 65.1 0.0 7.3e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OWF56592.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF3546 PF12066.8 OWF56594.1 - 0.065 13.4 1.6 0.16 12.2 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) Complex1_LYR_1 PF13232.6 OWF56595.1 - 0.015 15.9 26.5 5.2 7.7 0.3 6.9 1 1 7 8 8 8 0 Complex1_LYR-like Fungal_trans PF04082.18 OWF56595.1 - 3.3 6.7 27.0 1.1 8.2 2.5 4.5 1 1 2 3 3 3 0 Fungal specific transcription factor domain Pox_L3_FP4 PF03339.14 OWF56595.1 - 7.9 5.4 16.6 12 4.7 0.2 5.5 1 1 5 7 7 7 0 Poxvirus L3/FP4 protein RTP1_C1 PF10363.9 OWF56596.1 - 3.4e-05 24.0 24.5 1.6 8.9 0.1 7.5 1 1 7 8 8 8 6 Required for nuclear transport of RNA pol II C-terminus 1 Pentapeptide_4 PF13599.6 OWF56596.1 - 0.2 11.8 0.0 9.8 6.4 0.0 3.3 2 2 0 2 2 2 0 Pentapeptide repeats (9 copies) Syntaxin-6_N PF09177.11 OWF56597.1 - 0.065 13.8 2.4 0.27 11.8 0.1 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Nse4_C PF08743.10 OWF56598.1 - 8.1e-26 90.1 0.1 2e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OWF56598.1 - 0.00072 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE GMC_oxred_C PF05199.13 OWF56598.1 - 0.096 13.2 0.3 0.75 10.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Xan_ur_permease PF00860.20 OWF56599.1 - 4e-59 200.3 21.6 5.4e-59 199.8 21.6 1.1 1 0 0 1 1 1 1 Permease family DUF2613 PF11021.8 OWF56599.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) Ribosomal_L29 PF00831.23 OWF56600.1 - 0.82 9.7 4.8 0.51 10.3 0.5 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein APH PF01636.23 OWF56601.1 - 1e-11 45.3 0.0 1.6e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OWF56601.1 - 0.004 16.8 0.0 0.17 11.5 0.0 2.5 2 1 1 3 3 3 1 RIO1 family VWA_2 PF13519.6 OWF56602.1 - 2.2e-22 79.7 0.1 2e-21 76.6 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 OWF56602.1 - 1.9e-08 34.4 0.1 4e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OWF56602.1 - 8.7e-08 31.6 15.0 0.0015 18.3 1.5 4.0 3 0 0 3 3 3 2 Ubiquitin interaction motif TerB_N PF13208.6 OWF56602.1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 TerB N-terminal domain RAP80_UIM PF18282.1 OWF56602.1 - 1.2 9.0 8.1 0.28 11.0 0.3 3.1 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif RCC1 PF00415.18 OWF56603.1 - 5.7e-31 106.9 14.3 1.4e-10 41.6 0.6 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OWF56603.1 - 6.4e-20 70.4 20.6 3.3e-08 33.1 0.4 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat FAM153 PF15722.5 OWF56604.1 - 0.021 15.2 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 FAM153 family Ank_2 PF12796.7 OWF56605.1 - 3.8e-27 94.7 6.8 3.7e-08 33.9 0.1 5.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OWF56605.1 - 2.5e-23 82.2 7.0 5.5e-07 30.0 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56605.1 - 1e-19 68.5 1.3 0.04 14.5 0.0 8.2 7 1 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OWF56605.1 - 3.6e-18 65.1 4.2 0.01 16.2 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OWF56605.1 - 8.6e-16 57.8 3.3 0.0054 17.0 0.0 6.5 5 1 1 7 7 7 4 Ankyrin repeats (many copies) TAL_FSA PF00923.19 OWF56605.1 - 0.013 14.9 0.2 0.61 9.4 0.0 2.6 2 1 0 3 3 3 0 Transaldolase/Fructose-6-phosphate aldolase OpuAC PF04069.12 OWF56605.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system BPL_LplA_LipB PF03099.19 OWF56606.1 - 2.3e-17 63.1 0.0 6.2e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 OWF56606.1 - 1.4e-10 40.8 0.0 0.00015 21.0 0.0 2.3 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_C PF02237.17 OWF56606.1 - 1.7e-09 37.5 0.0 4.6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Glyco_hydro_9 PF00759.19 OWF56607.1 - 1.8e-132 442.7 11.3 1.8e-132 442.7 11.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 Med13_C PF06333.12 OWF56607.1 - 5.2 6.2 25.4 4.4 6.5 12.8 3.0 3 0 0 3 3 3 0 Mediator complex subunit 13 C-terminal domain SWIB PF02201.18 OWF56608.1 - 2.7e-20 72.0 0.0 6.3e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OWF56608.1 - 1.6e-16 60.0 1.6 1.6e-16 60.0 1.6 1.9 2 0 0 2 2 2 1 DEK C terminal domain TFIIF_alpha PF05793.12 OWF56608.1 - 0.0031 16.2 29.4 0.0041 15.8 29.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 OWF56608.1 - 0.015 14.9 21.5 0.021 14.4 21.5 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 OWF56608.1 - 0.13 10.5 24.5 0.17 10.1 24.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 OWF56608.1 - 0.48 8.9 13.2 0.62 8.6 13.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator LAP1C PF05609.12 OWF56608.1 - 0.68 8.9 20.1 0.9 8.6 20.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 OWF56608.1 - 0.74 6.9 3.1 0.83 6.7 3.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BUD22 PF09073.10 OWF56608.1 - 1.2 8.4 33.2 1.6 8.0 33.2 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OWF56608.1 - 2.7 7.3 35.9 3.5 6.9 35.9 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 OWF56608.1 - 2.9 6.8 10.0 3.8 6.4 10.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCSAP PF15748.5 OWF56608.1 - 8.7 6.4 22.4 13 5.9 22.4 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Ferritin PF00210.24 OWF56609.1 - 7.6e-15 55.1 0.7 1e-14 54.6 0.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain Ferritin PF00210.24 OWF56610.1 - 5e-24 84.8 2.8 4.4e-23 81.8 2.8 1.9 1 1 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 OWF56610.1 - 0.0038 17.6 0.1 0.0064 16.9 0.1 1.4 1 0 0 1 1 1 1 Rubrerythrin YHYH PF14240.6 OWF56611.1 - 6.6e-38 130.6 2.7 9.4e-11 42.0 0.0 4.7 2 2 2 4 4 4 4 YHYH protein PRTase_2 PF15609.6 OWF56612.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase Fz PF01392.22 OWF56613.1 - 1.8e-28 99.4 3.0 3e-28 98.6 3.0 1.3 1 0 0 1 1 1 1 Fz domain Ldl_recept_b PF00058.17 OWF56613.1 - 0.0012 19.3 0.7 0.0055 17.2 0.1 2.5 2 1 1 3 3 3 1 Low-density lipoprotein receptor repeat class B 4HB_MCP_1 PF12729.7 OWF56614.1 - 0.0017 17.9 1.3 0.0032 17.0 1.2 1.5 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction Apolipoprotein PF01442.18 OWF56614.1 - 0.0023 17.8 0.9 0.003 17.4 0.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 OWF56614.1 - 0.0055 16.3 2.0 0.0062 16.2 2.0 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF1640 PF07798.11 OWF56614.1 - 0.15 12.1 5.2 0.28 11.2 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF883 PF05957.13 OWF56614.1 - 0.36 11.5 8.7 3.9 8.1 2.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Imm64 PF15600.6 OWF56614.1 - 2.3 7.8 13.1 0.74 9.5 1.0 3.0 1 1 2 3 3 3 0 Immunity protein 64 Apolipoprotein PF01442.18 OWF56615.1 - 8.3e-07 29.1 1.1 1.1e-06 28.7 1.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain RRN3 PF05327.11 OWF56615.1 - 0.027 13.1 1.3 0.03 12.9 1.0 1.3 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF883 PF05957.13 OWF56615.1 - 0.043 14.4 10.8 2.6 8.7 5.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 OWF56615.1 - 0.15 9.9 2.2 0.21 9.5 2.1 1.3 1 1 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 OWF56615.1 - 0.37 10.3 4.2 0.42 10.1 4.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ExoD PF06055.12 OWF56615.1 - 2.5 7.4 14.4 2.6 7.4 0.9 2.8 1 1 3 4 4 4 0 Exopolysaccharide synthesis, ExoD Apolipoprotein PF01442.18 OWF56616.1 - 0.00073 19.5 1.1 0.00088 19.2 1.1 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 OWF56616.1 - 0.022 14.8 3.7 0.1 12.6 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) VirionAssem_T7 PF11653.8 OWF56616.1 - 0.13 12.8 6.8 9.6 6.8 0.1 3.0 1 1 2 3 3 3 0 Bacteriophage T7 virion assembly protein DUF883 PF05957.13 OWF56616.1 - 0.13 12.9 7.9 0.31 11.7 4.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) COG5 PF10392.9 OWF56616.1 - 0.17 12.0 1.3 1.6 8.9 1.2 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 ExoD PF06055.12 OWF56616.1 - 0.83 9.0 13.5 0.44 9.9 1.9 2.9 1 1 2 3 3 3 0 Exopolysaccharide synthesis, ExoD Ribosomal_S20p PF01649.18 OWF56616.1 - 5.4 7.7 16.3 3.3 8.4 1.7 3.2 1 1 1 2 2 2 0 Ribosomal protein S20 Ntox17 PF15524.6 OWF56616.1 - 8.7 6.7 6.7 23 5.3 0.5 3.1 1 1 2 3 3 3 0 Novel toxin 17 4HB_MCP_1 PF12729.7 OWF56617.1 - 0.0031 17.1 0.1 5.1 6.6 0.0 2.9 1 1 1 3 3 3 2 Four helix bundle sensory module for signal transduction DBINO PF13892.6 OWF56617.1 - 0.036 14.4 15.1 0.56 10.6 7.2 2.6 1 1 1 2 2 2 0 DNA-binding domain Endonuc-FokI_C PF09254.11 OWF56617.1 - 0.12 11.6 0.8 0.19 11.0 0.6 1.4 1 1 0 1 1 1 0 Restriction endonuclease FokI, C terminal Histidinol_dh PF00815.20 OWF56617.1 - 0.15 11.0 0.6 4.5 6.2 0.1 2.3 1 1 0 2 2 2 0 Histidinol dehydrogenase PI3K_P85_iSH2 PF16454.5 OWF56617.1 - 0.6 9.7 6.3 0.23 11.1 2.1 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SAM_2 PF07647.17 OWF56620.1 - 1.7e-13 50.4 0.4 3.9e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OWF56620.1 - 1.1e-09 38.6 0.5 0.00018 21.9 0.0 3.2 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) Chitin_synth_2 PF03142.15 OWF56620.1 - 3.4e-09 35.9 18.9 1.1e-08 34.2 0.3 4.4 4 1 1 5 5 5 3 Chitin synthase Glyco_trans_2_3 PF13632.6 OWF56620.1 - 0.0016 18.4 1.9 0.0016 18.4 1.9 3.5 3 1 1 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OWF56620.1 - 0.0043 17.0 0.3 0.0083 16.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Sulfotransfer_1 PF00685.27 OWF56621.1 - 2.2e-11 43.7 0.1 4.4e-11 42.8 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OWF56621.1 - 8.5e-10 39.4 0.1 1.2e-09 38.9 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 OWF56621.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain DnaJ PF00226.31 OWF56622.1 - 5.1e-19 68.2 2.5 8.3e-19 67.5 0.9 2.2 2 0 0 2 2 2 1 DnaJ domain ECM11 PF15463.6 OWF56622.1 - 0.049 14.2 0.7 0.049 14.2 0.7 2.0 2 0 0 2 2 2 0 Extracellular mutant protein 11 RRM_8 PF11835.8 OWF56622.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain WBS_methylT PF12589.8 OWF56623.1 - 3.4e-21 75.8 7.8 5.8e-21 75.1 7.8 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 OWF56623.1 - 2.2e-12 47.4 0.0 3.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OWF56623.1 - 3.2e-12 47.0 0.0 6.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OWF56623.1 - 1.4e-05 25.0 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF56623.1 - 5.4e-05 23.9 0.0 0.00024 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OWF56623.1 - 5.8e-05 23.0 0.0 9.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OWF56623.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 OWF56623.1 - 0.025 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) YfkD PF14167.6 OWF56623.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 YfkD-like protein Ras PF00071.22 OWF56624.1 - 5e-50 169.3 0.0 5.9e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56624.1 - 7.1e-33 113.4 0.0 1.3e-32 112.5 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56624.1 - 4.3e-11 42.6 0.0 7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OWF56624.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OWF56624.1 - 0.0011 19.3 0.2 0.012 16.0 0.2 2.2 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 OWF56624.1 - 0.0053 16.3 0.2 0.031 13.8 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OWF56624.1 - 0.0058 16.4 1.1 2 8.1 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OWF56624.1 - 0.0089 15.4 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 OWF56624.1 - 0.014 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 OWF56624.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OWF56624.1 - 0.021 14.8 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FixO PF02433.15 OWF56624.1 - 0.052 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO AAA_24 PF13479.6 OWF56624.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OWF56624.1 - 0.09 12.3 0.3 0.24 10.9 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 OWF56624.1 - 0.15 11.5 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 OWF56624.1 - 0.16 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 OWF56624.1 - 0.18 11.9 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OWF56624.1 - 0.21 10.7 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Ras PF00071.22 OWF56625.1 - 4.3e-37 127.2 0.0 5.2e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56625.1 - 6.4e-19 68.3 0.0 1.4e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56625.1 - 1e-05 25.1 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF56625.1 - 0.0099 15.4 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 OWF56625.1 - 0.03 14.6 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Mid domain of argonaute RNA_helicase PF00910.22 OWF56625.1 - 0.079 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Syntaxin PF00804.25 OWF56626.1 - 3.8e-63 212.8 16.3 3.8e-63 212.8 16.3 1.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 OWF56626.1 - 3.4e-19 68.6 9.8 8.6e-19 67.3 4.0 3.0 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.6 OWF56626.1 - 7.2e-11 42.4 6.8 7.2e-11 42.4 6.8 2.2 1 1 1 2 2 2 1 Syntaxin-like protein Lzipper-MIP1 PF14389.6 OWF56626.1 - 0.0048 17.2 1.3 0.07 13.4 0.2 2.4 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Baculo_11_kDa PF06143.11 OWF56626.1 - 0.0066 16.0 1.1 0.016 14.8 1.1 1.8 1 0 0 1 1 1 1 Baculovirus 11 kDa family T2SSF PF00482.23 OWF56626.1 - 0.044 13.7 5.2 0.041 13.8 2.3 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F WXG100 PF06013.12 OWF56626.1 - 0.047 13.9 1.7 1.9 8.8 0.1 3.6 2 2 1 3 3 3 0 Proteins of 100 residues with WXG COG5 PF10392.9 OWF56626.1 - 0.067 13.4 4.7 1.3 9.2 0.9 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Sec34 PF04136.15 OWF56626.1 - 0.084 12.8 6.4 0.84 9.5 1.7 2.8 2 1 0 2 2 2 0 Sec34-like family DUF4658 PF15555.6 OWF56626.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Nup54 PF13874.6 OWF56626.1 - 0.11 12.6 12.3 0.7 10.0 6.2 3.1 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 MCPsignal PF00015.21 OWF56626.1 - 0.12 12.1 11.0 0.39 10.5 0.6 3.1 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.11 OWF56626.1 - 0.29 11.7 8.5 0.069 13.7 2.1 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal YtxH PF12732.7 OWF56626.1 - 0.32 11.6 9.2 0.17 12.4 0.4 3.5 2 2 1 3 3 3 0 YtxH-like protein LMBR1 PF04791.16 OWF56626.1 - 0.55 9.1 11.2 0.96 8.3 11.2 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein TraF_2 PF13729.6 OWF56626.1 - 0.71 9.2 5.5 0.31 10.4 0.9 2.3 2 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF848 PF05852.11 OWF56626.1 - 0.88 9.7 11.1 0.17 12.0 3.1 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Laminin_II PF06009.12 OWF56626.1 - 1.2 9.2 11.8 2.3 8.2 3.6 2.6 2 1 1 3 3 3 0 Laminin Domain II DUF2703 PF10865.8 OWF56626.1 - 1.5 9.0 5.6 0.98 9.6 1.7 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2703) PEP-utilisers_N PF05524.13 OWF56626.1 - 1.8 8.7 7.7 0.8 9.9 0.6 2.8 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal LOH1CR12 PF10158.9 OWF56626.1 - 2 8.5 9.3 4.6 7.3 2.4 2.4 2 0 0 2 2 2 0 Tumour suppressor protein DUF2203 PF09969.9 OWF56626.1 - 3.4 8.4 13.4 7.8 7.2 2.0 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fez1 PF06818.15 OWF56626.1 - 3.6 8.0 16.3 1 9.8 0.8 2.4 2 1 0 2 2 2 0 Fez1 ISG65-75 PF11727.8 OWF56626.1 - 5.1 6.2 10.6 0.22 10.7 2.2 2.2 2 1 0 2 2 2 0 Invariant surface glycoprotein Orf78 PF06024.12 OWF56626.1 - 5.6 7.3 8.8 0.29 11.4 2.0 2.4 2 1 0 2 2 2 0 Orf78 (ac78) DUF4404 PF14357.6 OWF56626.1 - 6.7 7.4 11.1 3.6 8.3 3.2 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4404) DUF4600 PF15372.6 OWF56626.1 - 7.5 7.0 13.8 0.6 10.6 6.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) Tcp10_C PF07202.13 OWF56627.1 - 5e-84 280.6 5.2 5e-84 280.6 5.2 2.6 3 0 0 3 3 3 1 T-complex protein 10 C-terminus Shugoshin_N PF07558.11 OWF56627.1 - 1.2 9.1 10.6 0.99 9.3 2.3 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 OWF56627.1 - 4.6 7.6 23.0 12 6.3 3.0 4.4 2 2 1 3 3 3 0 TSC-22/dip/bun family DUF4807 PF16065.5 OWF56628.1 - 3.4e-40 136.6 0.7 4.8e-40 136.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) 7tm_2 PF00002.24 OWF56629.1 - 9.9e-10 38.1 20.8 1.7e-09 37.4 20.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 OWF56629.1 - 8.8e-05 22.8 17.9 0.0033 17.8 7.2 3.1 2 0 0 2 2 2 2 Somatomedin B domain DUF1720 PF08226.11 OWF56629.1 - 0.0012 19.2 8.9 9.3 6.7 8.9 3.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1720) Desulfoferrodox PF01880.18 OWF56629.1 - 0.049 14.2 0.9 9.4 6.9 0.0 3.8 4 0 0 4 4 4 0 Desulfoferrodoxin LisH PF08513.11 OWF56629.1 - 0.53 10.3 3.0 5.4 7.1 0.9 2.6 2 0 0 2 2 2 0 LisH Spt4 PF06093.13 OWF56629.1 - 5.7 7.1 6.9 14 5.9 0.1 3.5 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger Somatomedin_B PF01033.17 OWF56630.1 - 0.00038 20.8 16.7 0.0014 19.0 6.8 3.3 2 0 0 2 2 2 2 Somatomedin B domain HRM PF02793.22 OWF56630.1 - 3.7 7.9 13.4 9.9 6.5 0.1 4.5 4 0 0 4 4 4 0 Hormone receptor domain Kazal_2 PF07648.15 OWF56631.1 - 1.1e-14 54.2 9.9 8.2e-08 32.3 2.6 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OWF56631.1 - 1.3e-08 34.7 14.1 2.2e-05 24.3 2.2 2.5 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain LVIVD PF08309.11 OWF56632.1 - 0.0067 15.7 0.2 0.079 12.3 0.0 2.8 3 0 0 3 3 3 1 LVIVD repeat Adeno_PVIII PF01310.18 OWF56632.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Carb_anhydrase PF00194.21 OWF56633.1 - 3.3e-95 318.4 0.0 3.9e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HTH_34 PF13601.6 OWF56634.1 - 0.1 12.8 15.2 12 6.1 0.4 5.7 2 2 6 8 8 8 0 Winged helix DNA-binding domain NYN_YacP PF05991.11 OWF56634.1 - 0.24 11.3 1.3 2.2 8.2 0.0 3.5 3 0 0 3 3 3 0 YacP-like NYN domain DCP2 PF05026.13 OWF56634.1 - 2.4 8.6 15.9 84 3.6 0.0 8.0 11 2 2 13 13 13 0 Dcp2, box A domain Phage_GPL PF05926.11 OWF56634.1 - 3 7.9 22.9 1.1e+02 2.7 0.1 10.4 2 2 7 13 13 13 0 Phage head completion protein (GPL) SoDot-IcmSS PF16848.5 OWF56634.1 - 5.1 7.0 12.5 34 4.4 0.1 4.9 2 1 4 6 6 6 0 Substrate of the Dot/Icm secretion system, putative HTH_18 PF12833.7 OWF56634.1 - 7.6 6.9 9.8 62 4.0 0.2 5.1 2 1 3 5 5 5 0 Helix-turn-helix domain Enterotoxin_b PF01376.18 OWF56635.1 - 0.0018 18.4 7.5 74 3.6 0.1 7.4 1 1 9 10 10 10 2 Heat-labile enterotoxin beta chain Yippee-Mis18 PF03226.14 OWF56636.1 - 5.6e-13 49.0 0.5 7.1e-13 48.7 0.5 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 OWF56636.1 - 0.034 14.3 0.3 0.034 14.3 0.3 1.7 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling CBM_14 PF01607.24 OWF56637.1 - 5.9e-19 68.0 19.7 1.3e-11 44.4 4.0 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 OWF56638.1 - 1.4e-18 66.7 17.4 1.8e-12 47.2 6.8 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain CPW_WPC PF09717.10 OWF56638.1 - 0.52 11.3 8.4 0.4 11.7 2.5 2.3 2 1 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Fibrinogen_C PF00147.18 OWF56640.1 - 1.1e-31 110.3 6.7 1.1e-31 110.3 6.7 1.5 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain SIR2 PF02146.17 OWF56641.1 - 4.3e-53 179.8 0.0 7.8e-53 179.0 0.0 1.4 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OWF56641.1 - 0.026 14.2 0.0 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-TFIIB PF13453.6 OWF56641.1 - 0.033 13.5 0.1 0.033 13.5 0.1 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger A_deamin PF02137.18 OWF56641.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain NIF3 PF01784.18 OWF56642.1 - 4.6e-73 245.8 0.0 6.3e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Pkinase PF00069.25 OWF56643.1 - 9.6e-72 241.5 0.0 1.3e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56643.1 - 1.3e-31 109.8 0.0 2.9e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OWF56643.1 - 5.8e-12 45.8 0.0 1.2e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 OWF56643.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OWF56643.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 OWF56643.1 - 0.0037 17.6 0.0 0.12 12.7 0.0 2.8 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 OWF56643.1 - 0.0087 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OWF56643.1 - 0.036 13.0 0.1 0.054 12.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OWF56643.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DED PF01335.21 OWF56644.1 - 2.6e-11 43.7 5.1 4.2e-10 39.8 0.2 4.1 4 1 0 4 4 3 1 Death effector domain AAA_22 PF13401.6 OWF56644.1 - 7.3e-05 23.1 0.6 0.00071 19.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain TPR_19 PF14559.6 OWF56644.1 - 0.00043 20.7 0.0 0.16 12.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat PhoH PF02562.16 OWF56644.1 - 0.0006 19.3 0.1 0.0065 15.9 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 OWF56644.1 - 0.011 16.2 0.1 0.055 13.9 0.1 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OWF56644.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 OWF56644.1 - 0.012 14.8 1.2 0.026 13.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OWF56644.1 - 0.038 13.5 0.1 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OWF56644.1 - 0.046 12.8 0.1 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein HBS1_N PF08938.10 OWF56644.1 - 0.085 13.2 0.6 12 6.3 0.1 3.6 3 0 0 3 3 3 0 HBS1 N-terminus NACHT PF05729.12 OWF56644.1 - 0.089 12.7 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 NACHT domain TPR_12 PF13424.6 OWF56644.1 - 0.16 12.3 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RSS_P20 PF11757.8 OWF56644.1 - 1.1 9.8 6.7 0.24 11.8 0.2 3.4 4 0 0 4 4 4 0 Suppressor of RNA silencing P21-like N-terminal domain FHA PF00498.26 OWF56645.1 - 1.5e-08 34.8 0.2 2.7e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 FHA domain DED PF01335.21 OWF56646.1 - 3.4e-12 46.5 6.5 4.7e-12 46.0 1.7 3.5 3 1 1 4 4 4 1 Death effector domain PhoH PF02562.16 OWF56646.1 - 2.8e-05 23.7 0.7 0.00032 20.2 0.2 2.7 2 1 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 OWF56646.1 - 0.00024 21.4 0.2 0.0016 18.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 OWF56646.1 - 0.002 17.5 2.2 0.068 12.5 0.0 2.7 2 1 0 2 2 2 1 KaiC TsaE PF02367.17 OWF56646.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OWF56646.1 - 0.019 14.0 0.7 0.062 12.3 0.1 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein HBS1_N PF08938.10 OWF56646.1 - 0.07 13.4 0.3 3.2 8.1 0.0 3.4 3 0 0 3 3 3 0 HBS1 N-terminus NACHT PF05729.12 OWF56646.1 - 0.09 12.7 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 NACHT domain DUF3072 PF11272.8 OWF56646.1 - 0.15 12.0 0.3 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) TPR_2 PF07719.17 OWF56647.1 - 7.8e-25 85.0 17.9 0.0018 18.3 0.1 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 OWF56647.1 - 1.4e-23 81.7 18.1 0.00052 19.7 0.2 9.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 OWF56647.1 - 2.5e-19 69.6 15.6 3.1e-05 24.4 0.1 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OWF56647.1 - 1.6e-17 62.7 17.7 0.0044 17.7 0.1 9.0 6 3 3 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 OWF56647.1 - 2.9e-14 53.1 18.2 0.045 14.1 0.0 7.5 6 2 0 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 OWF56647.1 - 1.3e-12 48.1 7.9 0.00023 21.7 1.0 6.6 6 2 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OWF56647.1 - 4.7e-12 46.0 22.3 0.0037 17.5 0.2 6.7 5 2 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OWF56647.1 - 7.1e-11 41.4 14.9 0.26 11.6 0.2 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 OWF56647.1 - 1.4e-10 40.7 15.9 0.5 10.1 0.0 7.9 7 2 1 8 8 8 3 TPR repeat TPR_21 PF09976.9 OWF56647.1 - 0.00018 21.3 6.5 0.14 11.9 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 OWF56647.1 - 0.00038 19.3 0.0 0.0075 15.0 0.0 2.7 2 1 1 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 OWF56647.1 - 0.0016 18.3 12.4 0.55 10.4 0.0 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF56647.1 - 0.002 18.4 23.0 12 6.5 0.0 8.9 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OWF56647.1 - 0.0057 17.2 19.8 5.1 8.0 0.1 8.2 8 1 1 9 9 9 1 Tetratricopeptide repeat BTAD PF03704.17 OWF56647.1 - 0.014 15.8 7.6 0.52 10.7 0.3 4.0 4 0 0 4 4 4 0 Bacterial transcriptional activator domain ChAPs PF09295.10 OWF56647.1 - 0.015 14.4 1.5 0.22 10.5 0.3 2.7 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 OWF56647.1 - 0.026 14.2 0.8 7.5 6.2 0.0 3.6 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 OWF56647.1 - 0.037 14.4 2.4 41 4.6 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Lambda_Kil PF06301.11 OWF56647.1 - 0.13 11.8 0.1 18 5.0 0.1 3.5 4 0 0 4 4 4 0 Bacteriophage lambda Kil protein TPR_10 PF13374.6 OWF56647.1 - 0.3 11.0 9.4 1.8 8.5 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 OWF56647.1 - 3.5 7.7 9.0 6.8 6.8 1.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M10 PF00413.24 OWF56648.1 - 1.8e-49 167.6 0.4 2.7e-49 167.0 0.4 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 OWF56648.1 - 1.5e-08 34.4 0.3 8.9e-08 32.0 0.1 2.5 2 0 0 2 2 2 1 Hemopexin PG_binding_1 PF01471.18 OWF56648.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 OWF56648.1 - 0.0014 19.1 0.1 0.0024 18.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OWF56648.1 - 0.0095 15.6 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OWF56648.1 - 0.015 15.5 0.2 0.025 14.7 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 OWF56648.1 - 0.031 13.2 0.5 0.048 12.6 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 OWF56648.1 - 0.038 13.6 0.1 0.32 10.6 0.1 2.1 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DUF4953 PF16313.5 OWF56648.1 - 0.041 13.1 0.3 0.066 12.4 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M43 PF05572.13 OWF56648.1 - 0.059 13.3 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 OWF56649.1 - 4.2e-48 163.2 0.0 6.4e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Astacin PF01400.24 OWF56649.1 - 0.00097 18.8 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 OWF56649.1 - 0.0069 16.0 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OWF56649.1 - 0.017 15.6 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 OWF56649.1 - 0.062 12.5 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 OWF56649.1 - 0.09 12.9 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Pro_dh PF01619.18 OWF56650.1 - 2.1e-62 211.4 0.2 2.7e-62 211.0 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh PF01619.18 OWF56651.1 - 9.5e-62 209.2 0.8 1.1e-61 208.9 0.8 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DUF3447 PF11929.8 OWF56651.1 - 0.077 13.0 1.3 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) p450 PF00067.22 OWF56652.1 - 2.6e-94 316.6 0.0 3e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF56653.1 - 1.1e-99 334.3 0.0 1.3e-99 334.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF56654.1 - 8.2e-110 367.7 0.0 9.9e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF56656.1 - 7.2e-103 344.8 0.0 8e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBM_14 PF01607.24 OWF56657.1 - 5.3e-19 68.1 14.7 1.8e-11 44.1 2.4 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain VWA PF00092.28 OWF56657.1 - 6e-05 23.4 0.3 8e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4262 PF14081.6 OWF56657.1 - 0.19 11.9 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) SSF PF00474.17 OWF56658.1 - 1.8e-133 445.3 24.6 2.7e-133 444.8 24.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ca_hom_mod PF14798.6 OWF56658.1 - 0.051 12.7 0.0 0.051 12.7 0.0 2.2 3 0 0 3 3 3 0 Calcium homeostasis modulator Ion_trans_2 PF07885.16 OWF56659.1 - 5.4e-34 116.0 18.1 1e-17 63.9 0.3 2.6 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OWF56659.1 - 2.2e-05 23.8 9.9 0.00071 18.9 0.2 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 OWF56659.1 - 0.16 11.8 0.3 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Ependymin PF00811.18 OWF56662.1 - 8.5e-32 110.1 2.2 4.1e-15 56.2 0.2 2.3 2 0 0 2 2 2 2 Ependymin adh_short PF00106.25 OWF56663.1 - 8.2e-29 100.4 0.0 1.2e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OWF56663.1 - 1.7e-23 83.4 0.0 2.2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OWF56663.1 - 2.6e-08 34.0 0.0 5.1e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 KR domain TRAM_LAG1_CLN8 PF03798.16 OWF56664.1 - 1.5e-23 83.6 22.2 2.4e-23 82.9 22.2 1.3 1 0 0 1 1 1 1 TLC domain DUF3943 PF13084.6 OWF56664.1 - 0.043 13.7 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) zf-C2H2_4 PF13894.6 OWF56665.1 - 8.8e-05 23.0 13.6 0.0016 19.1 1.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF56665.1 - 0.011 16.1 1.5 0.011 16.1 1.5 3.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 OWF56665.1 - 0.035 14.4 2.8 0.067 13.5 2.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PsaD PF02531.16 OWF56665.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 PsaD zf-C2H2_11 PF16622.5 OWF56665.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type ADD_ATRX PF17981.1 OWF56665.1 - 0.26 11.2 4.3 0.73 9.7 0.8 2.8 2 1 1 3 3 3 0 Cysteine Rich ADD domain ABC_membrane PF00664.23 OWF56666.1 - 1.3e-55 188.9 15.3 2.4e-55 188.1 15.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OWF56666.1 - 8.4e-32 110.5 0.0 2.2e-31 109.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OWF56666.1 - 1.3e-09 37.8 0.9 4e-08 33.0 0.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane_3 PF13748.6 OWF56666.1 - 0.00048 19.4 3.4 0.0012 18.1 3.4 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 OWF56666.1 - 0.0047 17.3 0.1 0.013 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OWF56666.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OWF56666.1 - 0.031 14.5 1.8 0.17 12.1 0.3 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 OWF56666.1 - 0.054 13.9 2.1 6 7.3 0.2 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OWF56666.1 - 0.063 13.0 0.1 0.22 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 OWF56666.1 - 0.071 13.3 0.3 0.94 9.8 0.3 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 OWF56666.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRF-TF PF00319.18 OWF56666.1 - 0.14 11.7 0.0 0.42 10.1 0.0 1.8 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) ATG16 PF08614.11 OWF56667.1 - 0.85 9.8 40.8 0.11 12.7 11.5 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 OWF56667.1 - 2.6 8.4 7.4 15 5.9 0.0 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UNC-93 PF05978.16 OWF56668.1 - 3.7e-09 36.5 9.9 1.9e-08 34.2 9.8 2.4 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OWF56668.1 - 0.025 13.5 48.4 0.2 10.5 26.1 3.2 1 1 1 2 2 2 0 Major Facilitator Superfamily Phage_holin_4_2 PF04020.13 OWF56668.1 - 0.026 15.2 3.9 0.026 15.2 3.9 3.9 3 1 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV UNC-93 PF05978.16 OWF56669.1 - 5.7e-12 45.6 7.5 1.3e-11 44.4 7.5 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Glyco_trans_1_2 PF13524.6 OWF56670.1 - 0.073 13.5 0.0 0.084 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_21 PF05050.12 OWF56671.1 - 1.1e-09 38.5 0.2 2.9e-09 37.2 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 OWF56671.1 - 0.0021 17.4 0.1 0.014 14.7 0.1 2.0 1 1 0 1 1 1 1 Vibrio cholerae RfbT protein Ribosomal_S13 PF00416.22 OWF56672.1 - 3.2e-56 189.2 4.4 3.7e-56 189.0 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 OWF56672.1 - 0.018 13.8 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 OWF56672.1 - 0.053 13.8 0.1 0.2 11.9 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif Synapsin PF02078.16 OWF56673.1 - 3.4e-48 162.1 0.0 9.4e-48 160.7 0.0 1.7 2 0 0 2 2 2 1 Synapsin, N-terminal domain Synapsin_C PF02750.14 OWF56673.1 - 7.7e-19 68.0 0.1 1.2e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain TIMP PF00965.17 OWF56674.1 - 5e-30 104.7 12.5 5.9e-30 104.4 12.5 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase TIMP PF00965.17 OWF56675.1 - 1.1e-30 106.7 13.2 2.4e-30 105.7 13.2 1.5 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase Synapsin_C PF02750.14 OWF56676.1 - 1.8e-79 266.0 1.2 3e-79 265.3 1.2 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain DUF779 PF05610.11 OWF56676.1 - 0.08 13.2 5.6 17 5.7 1.0 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF779) TFIIA PF03153.13 OWF56676.1 - 0.085 12.8 12.5 0.14 12.2 12.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.22 OWF56677.1 - 5.6e-106 354.8 0.0 9.1e-106 354.1 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.19 OWF56677.1 - 4.2e-40 137.4 0.0 7.1e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 OWF56677.1 - 2.6e-12 46.8 0.1 1.2e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain PP-binding PF00550.25 OWF56677.1 - 7e-06 26.3 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.11 OWF56677.1 - 0.065 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) TIL PF01826.17 OWF56677.1 - 0.096 13.0 2.8 0.2 11.9 2.8 1.5 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Innate_immun PF12782.7 OWF56679.1 - 4.1 6.8 15.2 9.6 5.6 0.9 4.0 1 1 3 4 4 4 0 Invertebrate innate immunity transcript family ASFV_J13L PF05568.11 OWF56679.1 - 6.7 6.4 27.2 11 5.7 2.8 4.2 1 1 2 3 3 3 0 African swine fever virus J13L protein Innate_immun PF12782.7 OWF56681.1 - 0.037 13.5 8.7 0.52 9.8 0.6 2.5 1 1 1 2 2 2 0 Invertebrate innate immunity transcript family ASFV_J13L PF05568.11 OWF56681.1 - 0.054 13.3 12.5 0.63 9.8 1.7 3.0 1 1 2 3 3 3 0 African swine fever virus J13L protein Keratin_B2 PF01500.17 OWF56681.1 - 0.18 11.8 1.2 1.7 8.6 1.2 2.2 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein TNF PF00229.18 OWF56682.1 - 0.00021 21.2 0.0 0.00065 19.6 0.0 1.7 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family MFS_1 PF07690.16 OWF56683.1 - 4.4e-41 141.0 33.3 2.6e-23 82.5 7.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OWF56683.1 - 5.2e-12 45.8 13.5 5.6e-10 39.1 7.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB SpoVAB PF13782.6 OWF56683.1 - 5 7.5 9.4 0.33 11.2 0.9 2.6 2 0 0 2 2 2 0 Stage V sporulation protein AB zf-B_box PF00643.24 OWF56684.1 - 1.2e-08 34.9 19.8 7.8e-06 25.9 8.6 4.7 3 1 0 3 3 3 2 B-box zinc finger zf-RING_5 PF14634.6 OWF56684.1 - 4.8e-06 26.4 9.9 4.8e-06 26.4 9.9 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 OWF56684.1 - 4.8e-05 23.6 11.1 4.8e-05 23.6 11.1 3.7 3 1 0 3 3 3 1 Ring finger domain CEBP_ZZ PF16366.5 OWF56684.1 - 0.00067 19.8 23.2 0.12 12.6 1.9 3.6 3 0 0 3 3 3 3 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_2 PF13923.6 OWF56684.1 - 0.0026 17.5 9.7 0.0026 17.5 9.7 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF4359 PF14271.6 OWF56684.1 - 0.2 12.5 0.3 0.2 12.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) G2BR PF18442.1 OWF56684.1 - 0.48 10.1 2.8 0.41 10.3 1.1 1.7 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) Spectrin PF00435.21 OWF56685.1 - 0.0054 17.2 0.4 0.0073 16.8 0.4 1.2 1 0 0 1 1 1 1 Spectrin repeat MFS_1 PF07690.16 OWF56686.1 - 1.4e-25 89.9 21.4 6.9e-13 48.2 4.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF56686.1 - 0.049 12.5 16.3 0.048 12.5 0.9 2.6 2 1 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.16 OWF56687.1 - 8.2e-21 74.3 18.1 3.2e-14 52.6 0.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OWF56687.1 - 0.023 13.6 10.9 0.17 10.7 0.5 3.1 2 1 1 3 3 3 0 MFS_1 like family DUF4498 PF14926.6 OWF56688.1 - 7.7e-103 343.1 4.3 8.7e-103 342.9 4.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Lig_chan PF00060.26 OWF56689.1 - 2.1e-14 53.6 0.0 2.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel DUF3546 PF12066.8 OWF56690.1 - 0.066 13.4 1.6 0.16 12.2 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) Ras PF00071.22 OWF56691.1 - 2e-59 199.8 0.3 2.6e-59 199.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OWF56691.1 - 1.3e-36 125.4 0.1 2.2e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56691.1 - 1.2e-15 57.4 0.1 1.6e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF56691.1 - 3.1e-06 26.9 0.1 2e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OWF56691.1 - 3.4e-06 26.6 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OWF56691.1 - 2e-05 24.7 0.0 4.2e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OWF56691.1 - 0.00014 21.3 0.2 0.00017 21.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OWF56691.1 - 0.00039 20.4 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OWF56691.1 - 0.0065 16.0 0.1 0.076 12.5 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 OWF56691.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TetR_C_16 PF17920.1 OWF56691.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EGF_3 PF12947.7 OWF56693.1 - 0.0013 18.9 7.5 0.0013 18.9 7.5 2.4 2 0 0 2 2 2 1 EGF domain TNFR_c6 PF00020.18 OWF56693.1 - 0.0037 17.6 1.9 0.0037 17.6 1.9 4.5 4 0 0 4 4 4 2 TNFR/NGFR cysteine-rich region Myelin_PLP PF01275.19 OWF56693.1 - 0.022 14.6 4.2 0.079 12.8 0.0 3.4 3 0 0 3 3 3 0 Myelin proteolipid protein (PLP or lipophilin) TctB PF07331.11 OWF56693.1 - 0.045 14.0 2.0 0.17 12.1 0.4 2.7 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family MFMR_assoc PF16596.5 OWF56693.1 - 0.15 12.5 0.1 0.36 11.3 0.1 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR EphA2_TM PF14575.6 OWF56693.1 - 0.17 12.8 0.8 50 4.9 0.0 3.9 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain UL41A PF17591.2 OWF56693.1 - 7 6.8 6.9 59 3.9 0.1 4.2 4 0 0 4 4 4 0 Herpesvirus UL41A Zn-C2H2_12 PF18112.1 OWF56694.1 - 1.6 9.2 5.5 1.8e+02 2.7 0.1 4.3 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain EGF_CA PF07645.15 OWF56695.1 - 1.5e-06 28.3 10.4 1.5e-06 28.3 10.4 3.9 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF_3 PF12947.7 OWF56695.1 - 2.8e-05 24.2 7.0 2.8e-05 24.2 7.0 3.4 2 0 0 2 2 2 1 EGF domain TNFR_c6 PF00020.18 OWF56695.1 - 0.00017 21.9 11.2 0.00017 21.9 11.2 5.5 3 1 2 5 5 5 3 TNFR/NGFR cysteine-rich region cEGF PF12662.7 OWF56695.1 - 0.00057 19.7 1.5 0.00057 19.7 1.5 2.7 3 0 0 3 3 3 1 Complement Clr-like EGF-like DUF2585 PF10755.9 OWF56696.1 - 0.25 11.0 15.5 23 4.6 0.2 5.0 1 1 5 7 7 7 0 Protein of unknown function (DUF2585) UPF0449 PF15136.6 OWF56697.1 - 0.003 18.0 2.2 0.0038 17.7 2.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 Tropomyosin_1 PF12718.7 OWF56697.1 - 0.01 16.0 6.5 0.014 15.6 6.5 1.1 1 0 0 1 1 1 0 Tropomyosin like BRI3BP PF14965.6 OWF56697.1 - 0.038 13.5 0.2 0.038 13.5 0.2 1.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Comm PF15957.5 OWF56697.1 - 0.1 13.0 4.0 0.35 11.2 1.6 2.1 1 1 0 2 2 2 0 Commissureless Calc_CGRP_IAPP PF00214.19 OWF56697.1 - 0.14 12.6 1.9 0.18 12.2 1.9 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family XhlA PF10779.9 OWF56697.1 - 0.38 11.0 4.7 0.73 10.1 4.7 1.4 1 0 0 1 1 1 0 Haemolysin XhlA An_peroxidase PF03098.15 OWF56698.1 - 5.6e-157 523.5 0.0 7.6e-157 523.1 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase CooC_C PF15976.5 OWF56699.1 - 0.0028 17.6 1.7 0.99 9.5 0.1 2.8 1 1 2 3 3 3 2 CS1-pili formation C-terminal Sipho_tail PF05709.11 OWF56699.1 - 0.038 13.4 0.5 3.3 7.1 0.1 2.6 1 1 1 2 2 2 0 Phage tail protein DUF413 PF04219.12 OWF56699.1 - 0.12 12.4 5.8 8.6 6.5 0.3 3.7 1 1 3 4 4 4 0 Protein of unknown function, DUF PB1-F2 PF11986.8 OWF56699.1 - 1.5 9.1 10.1 16 5.8 0.2 3.4 1 1 2 3 3 3 0 Influenza A Proapoptotic protein IFT57 PF10498.9 OWF56700.1 - 0.0071 15.4 23.9 0.011 14.7 12.4 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 KELK PF15796.5 OWF56700.1 - 0.0095 16.4 10.0 0.49 10.9 1.5 2.2 1 1 1 2 2 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec34 PF04136.15 OWF56700.1 - 0.16 11.8 24.0 1.4 8.8 7.9 2.8 1 1 1 2 2 2 0 Sec34-like family CALCOCO1 PF07888.11 OWF56700.1 - 0.21 10.4 14.5 1 8.1 14.5 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc24 PF08286.11 OWF56700.1 - 0.26 11.6 23.5 1.8e+04 -6.2 23.5 3.2 1 1 0 1 1 0 0 Spc24 subunit of Ndc80 Myosin_tail_1 PF01576.19 OWF56700.1 - 0.31 8.8 14.2 0.35 8.6 14.2 1.0 1 0 0 1 1 1 0 Myosin tail Jnk-SapK_ap_N PF09744.9 OWF56700.1 - 0.36 11.1 26.9 2 8.7 9.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.8 OWF56700.1 - 0.4 10.1 7.4 1.6 8.1 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 OWF56700.1 - 0.47 11.0 13.6 3.3 8.2 13.5 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Cytadhesin_P30 PF07271.11 OWF56700.1 - 0.62 9.6 4.6 5.4 6.5 4.6 2.0 1 1 0 1 1 1 0 Cytadhesin P30/P32 DUF3450 PF11932.8 OWF56700.1 - 0.68 9.2 20.0 0.72 9.1 11.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 OWF56700.1 - 3.9 7.7 7.5 20 5.5 1.7 2.5 1 1 0 2 2 2 0 JNK-interacting protein leucine zipper II SHE3 PF17078.5 OWF56700.1 - 8.8 6.0 34.6 5.2 6.7 11.0 3.0 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 IgGFc_binding PF17517.2 OWF56701.1 - 6.4e-57 193.1 0.7 6.4e-57 193.1 0.7 2.0 2 0 0 2 2 2 2 IgGFc binding protein Cu-binding_MopE PF11617.8 OWF56702.1 - 0.025 14.7 5.8 0.025 14.7 5.8 2.6 2 0 0 2 2 2 0 Putative metal-binding motif FUN14 PF04930.15 OWF56702.1 - 0.19 12.2 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 FUN14 family SUR7 PF06687.12 OWF56702.1 - 2 8.0 5.8 26 4.3 6.6 2.2 1 1 1 2 2 2 0 SUR7/PalI family TMEM164 PF14808.6 OWF56703.1 - 5.7e-101 337.1 10.9 6.9e-101 336.9 10.9 1.1 1 0 0 1 1 1 1 TMEM164 family Voldacs PF03517.13 OWF56704.1 - 8.7e-32 110.1 1.4 1.2e-31 109.6 1.4 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Citrate_synt PF00285.21 OWF56704.1 - 0.013 14.6 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain PH_TFIIH PF08567.11 OWF56704.1 - 0.089 13.1 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain DUF1741 PF08427.10 OWF56704.1 - 0.23 11.1 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) JmjC PF02373.22 OWF56705.1 - 2.2e-28 99.0 1.5 2.2e-28 99.0 1.5 2.3 2 0 0 2 2 1 1 JmjC domain, hydroxylase TPR_1 PF00515.28 OWF56705.1 - 2.7e-22 77.6 11.6 1.3e-05 24.8 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 OWF56705.1 - 1.1e-11 43.9 11.4 0.23 11.7 0.9 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OWF56705.1 - 5.4e-10 39.4 9.5 0.028 14.7 0.0 5.7 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OWF56705.1 - 5.3e-09 35.6 11.5 0.053 13.7 0.8 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OWF56705.1 - 2e-08 34.8 5.2 0.0027 18.3 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OWF56705.1 - 4e-08 33.1 4.2 0.051 14.0 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OWF56705.1 - 2e-05 24.6 0.6 0.53 10.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OWF56705.1 - 0.00043 20.1 8.8 1.6 8.9 0.2 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF56705.1 - 0.00068 20.1 9.9 5.5 7.6 2.4 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OWF56705.1 - 0.0021 17.7 10.3 1.1 9.0 0.0 5.3 5 2 1 6 6 6 2 TPR repeat SNAP PF14938.6 OWF56705.1 - 0.0021 17.5 4.3 0.007 15.8 0.7 2.7 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 OWF56705.1 - 0.017 15.9 4.2 59 4.9 0.3 5.4 2 2 6 8 8 7 0 Tetratricopeptide repeat DUF1824 PF08854.10 OWF56705.1 - 0.077 12.9 0.2 4.1 7.3 0.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1824) TPR_6 PF13174.6 OWF56705.1 - 0.11 13.2 9.1 21 6.0 0.6 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Ku_C PF03730.14 OWF56705.1 - 0.52 11.1 3.7 33 5.3 1.4 2.8 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm ANAPC3 PF12895.7 OWF56705.1 - 2.6 8.3 8.6 1.5 9.1 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FUN14 PF04930.15 OWF56706.1 - 6.5e-23 81.0 8.4 1.2e-17 64.1 3.4 2.2 1 1 1 2 2 2 2 FUN14 family ApoLp-III PF07464.11 OWF56706.1 - 0.00069 19.7 0.4 0.001 19.2 0.4 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Myb_DNA-bind_6 PF13921.6 OWF56706.1 - 3.9 7.8 7.4 5.3 7.4 1.7 2.4 1 1 1 2 2 2 0 Myb-like DNA-binding domain Peptidase_M3 PF01432.20 OWF56707.1 - 9.8e-129 430.6 1.2 1.3e-128 430.2 1.2 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 OWF56707.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Effector protein SPRY PF00622.28 OWF56708.1 - 4.3e-20 72.0 0.0 6e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 OWF56708.1 - 5.4e-10 39.0 0.3 8.3e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OWF56708.1 - 3.1e-09 36.5 0.1 7.4e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 OWF56708.1 - 0.0018 17.8 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 F-box Ank_2 PF12796.7 OWF56709.1 - 2.9e-39 133.5 6.8 2.8e-11 43.9 0.1 5.1 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OWF56709.1 - 3.4e-30 103.1 9.5 8.5e-07 29.2 0.1 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OWF56709.1 - 1.9e-29 101.3 3.5 8.1e-06 26.0 0.0 7.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OWF56709.1 - 3.7e-29 100.7 1.4 1.6e-07 31.7 0.0 6.8 4 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OWF56709.1 - 4.5e-24 81.9 1.6 0.00073 19.8 0.0 8.6 9 0 0 9 9 8 4 Ankyrin repeat DUF3447 PF11929.8 OWF56709.1 - 0.0048 16.8 0.1 0.28 11.1 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) NACHT PF05729.12 OWF56709.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Flavi_NS1 PF00948.21 OWF56709.1 - 0.021 13.7 0.1 0.047 12.6 0.0 1.5 2 0 0 2 2 2 0 Flavivirus non-structural Protein NS1 RNA_helicase PF00910.22 OWF56709.1 - 0.023 15.1 0.0 0.073 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 OWF56709.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OWF56709.1 - 0.088 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OWF56709.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 KaiC VWA_3_C PF18571.1 OWF56709.1 - 0.21 11.5 1.0 1.7 8.6 0.0 3.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Peptidase_C14 PF00656.22 OWF56710.1 - 2.2e-32 113.0 0.1 3.3e-32 112.4 0.1 1.3 1 0 0 1 1 1 1 Caspase domain DED PF01335.21 OWF56710.1 - 0.065 13.6 0.4 0.065 13.6 0.4 2.2 2 0 0 2 2 2 0 Death effector domain Surfac_D-trimer PF09006.11 OWF56710.1 - 0.093 12.6 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation TSP_1 PF00090.19 OWF56712.1 - 5.1e-52 173.9 81.3 2.4e-11 43.7 9.9 5.8 6 0 0 6 6 6 5 Thrombospondin type 1 domain Amino_oxidase PF01593.24 OWF56713.1 - 4.3e-77 260.3 0.0 5.2e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF56713.1 - 3.1e-15 56.2 0.1 6.4e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF56713.1 - 2e-06 27.2 0.5 3.5e-06 26.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OWF56713.1 - 2.1e-06 27.6 0.0 3.3e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OWF56713.1 - 1.5e-05 24.4 0.2 2.4e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OWF56713.1 - 2e-05 24.0 0.7 3.4e-05 23.2 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OWF56713.1 - 2.1e-05 24.1 0.1 4.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF56713.1 - 3.5e-05 23.2 0.1 0.0015 17.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF56713.1 - 7.8e-05 21.6 0.4 0.0005 18.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OWF56713.1 - 0.00018 22.0 0.8 0.0018 18.8 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OWF56713.1 - 0.00033 20.0 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF56713.1 - 0.00085 18.5 0.0 0.0063 15.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 OWF56713.1 - 0.0012 18.0 0.5 0.006 15.7 0.0 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF56713.1 - 0.0071 15.7 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OWF56713.1 - 0.04 13.9 0.1 2 8.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding XdhC_C PF13478.6 OWF56713.1 - 0.081 13.4 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain Amino_oxidase PF01593.24 OWF56714.1 - 1.8e-77 261.6 0.0 2.2e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OWF56714.1 - 5.1e-14 52.3 0.2 1.1e-13 51.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OWF56714.1 - 1.5e-07 30.9 1.6 1.6e-07 30.8 0.7 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 OWF56714.1 - 1.6e-06 27.6 0.1 3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OWF56714.1 - 2.5e-06 26.9 0.6 8.6e-06 25.2 0.4 1.8 1 1 1 2 2 2 1 Thi4 family DAO PF01266.24 OWF56714.1 - 2.6e-06 27.3 0.3 1.2e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OWF56714.1 - 1.6e-05 24.5 0.5 1.6e-05 24.5 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OWF56714.1 - 2.4e-05 23.7 0.1 0.00019 20.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OWF56714.1 - 0.00011 21.0 0.9 0.00021 20.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OWF56714.1 - 0.0002 21.8 0.5 0.00058 20.4 0.2 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OWF56714.1 - 0.00031 19.9 0.1 0.002 17.2 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OWF56714.1 - 0.0018 17.6 0.4 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OWF56714.1 - 0.0026 16.9 0.1 0.0048 16.0 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OWF56714.1 - 0.0068 15.7 0.2 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 OWF56714.1 - 0.019 13.4 0.0 0.034 12.6 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 OWF56714.1 - 0.022 14.7 0.2 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding IlvN PF07991.12 OWF56714.1 - 0.052 13.1 0.2 0.12 12.0 0.1 1.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MCRA PF06100.11 OWF56714.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 OWF56714.1 - 0.13 12.1 0.3 0.25 11.2 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OWF56714.1 - 0.26 11.6 0.7 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 TrkA-N domain COX16 PF14138.6 OWF56717.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Shisa PF13908.6 OWF56717.1 - 0.021 15.0 1.8 0.097 12.9 0.0 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator SCIMP PF15050.6 OWF56717.1 - 0.068 13.6 0.2 0.18 12.3 0.0 1.8 1 1 1 2 2 2 0 SCIMP protein Glucos_trans_II PF14264.6 OWF56717.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII FAM176 PF14851.6 OWF56717.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Pet100 PF09803.9 OWF56717.1 - 0.71 10.4 2.7 0.86 10.2 1.0 2.1 2 1 0 2 2 2 0 Pet100 Abhydrolase_3 PF07859.13 OWF56718.1 - 4.9e-52 176.8 0.0 1.4e-39 136.2 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OWF56718.1 - 1e-09 37.9 0.1 3.3e-09 36.2 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OWF56718.1 - 1.7e-07 30.9 0.0 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OWF56718.1 - 0.0024 16.8 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase PhoPQ_related PF10142.9 OWF56718.1 - 0.064 11.9 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_2 PF02230.16 OWF56718.1 - 0.14 11.9 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2951 PF11166.8 OWF56719.1 - 0.039 14.1 0.0 0.084 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) P68HR PF08061.11 OWF56719.1 - 0.4 10.9 2.1 20 5.4 0.0 3.4 3 1 1 4 4 4 0 P68HR (NUC004) repeat Pox_E8 PF03394.13 OWF56720.1 - 0.12 12.0 2.4 1.6 8.3 0.8 2.1 1 1 1 2 2 2 0 Poxvirus E8 protein DUF2951 PF11166.8 OWF56722.1 - 0.024 14.8 0.1 5.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF4976 PF16347.5 OWF56722.1 - 0.09 13.0 0.2 8.7 6.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4976) PUD1_2 PF18457.1 OWF56722.1 - 0.2 11.6 1.0 13 5.8 0.1 2.1 1 1 1 2 2 2 0 Up-Regulated in long-lived daf-2 Pentapeptide_2 PF01469.18 OWF56722.1 - 0.36 10.8 9.3 0.32 10.9 0.4 3.3 4 0 0 4 4 4 0 Pentapeptide repeats (8 copies) Kinesin PF00225.23 OWF56723.1 - 2.6e-101 338.9 0.3 2.6e-101 338.9 0.3 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OWF56723.1 - 2.8e-17 63.0 0.8 9.4e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 OWF56723.1 - 5.9e-08 32.9 0.1 1.6e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OWF56723.1 - 2.4e-05 24.6 0.0 0.0001 22.6 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 OWF56723.1 - 0.00026 21.4 4.3 0.00034 21.0 0.3 3.0 2 0 0 2 2 2 1 Kinesin protein 1B C2-C2_1 PF11618.8 OWF56723.1 - 0.0043 17.1 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 Kinesin_assoc PF16183.5 OWF56723.1 - 0.012 15.8 9.5 0.012 15.8 9.5 4.8 3 1 1 4 4 4 0 Kinesin-associated EFP_N PF08207.12 OWF56723.1 - 0.029 14.4 0.1 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain UPF0242 PF06785.11 OWF56723.1 - 0.39 10.8 32.3 0.37 10.9 11.5 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 OWF56723.1 - 3.5 7.1 18.3 5.5 6.5 1.9 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit TNF PF00229.18 OWF56724.1 - 1.4e-12 47.6 1.0 2.2e-12 47.0 1.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF370 PF04025.12 OWF56725.1 - 0.00082 19.4 5.8 14 5.9 0.3 4.4 1 1 5 6 6 6 3 Domain of unknown function (DUF370) F-box-like PF12937.7 OWF56725.1 - 0.006 16.4 13.7 24 4.9 0.1 5.2 1 1 9 10 10 10 8 F-box-like HC2 PF07382.11 OWF56725.1 - 0.009 16.1 2.4 0.012 15.7 2.4 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 EpuA PF11772.8 OWF56725.1 - 0.043 13.5 12.0 94 2.8 0.1 7.9 1 1 9 10 10 10 0 DNA-directed RNA polymerase subunit beta DUF4632 PF15451.6 OWF56725.1 - 0.45 10.6 20.9 14 5.8 0.7 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4632) DUF4929 PF16283.5 OWF56726.1 - 0.078 12.0 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) TNF PF00229.18 OWF56727.1 - 1.3e-13 51.0 0.7 1.4e-13 50.9 0.7 1.1 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family SID-1_RNA_chan PF13965.6 OWF56728.1 - 0.0038 15.7 1.3 0.0046 15.4 1.3 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF2231 PF09990.9 OWF56728.1 - 0.04 14.3 1.3 0.07 13.6 1.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF4199 PF13858.6 OWF56728.1 - 0.066 13.6 2.9 0.13 12.6 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Terpene_synth_C PF03936.16 OWF56729.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain I-set PF07679.16 OWF56730.1 - 4.2e-37 126.1 0.0 5.1e-12 45.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 OWF56730.1 - 2e-36 124.4 0.1 2.4e-13 50.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 OWF56730.1 - 1.9e-20 73.0 0.1 1.6e-06 28.3 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 OWF56730.1 - 1.3e-18 66.9 1.0 5e-05 23.4 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 OWF56730.1 - 3e-17 62.8 2.8 2.1e-07 31.1 0.0 4.0 3 1 1 4 4 4 3 Immunoglobulin V-set domain V-set_CD47 PF08204.11 OWF56730.1 - 0.0045 17.0 4.9 0.12 12.4 0.1 3.9 4 1 0 4 4 4 1 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 OWF56730.1 - 0.012 15.7 0.1 0.084 12.9 0.0 2.3 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 OWF56730.1 - 0.012 15.2 0.4 8.9 6.0 0.0 3.2 3 0 0 3 3 3 0 Immunoglobulin domain TEBP_beta PF07404.11 OWF56731.1 - 1.4e-06 27.9 30.6 0.49 9.7 1.9 7.1 1 1 7 8 8 8 6 Telomere-binding protein beta subunit (TEBP beta) MBD_C PF14048.6 OWF56731.1 - 1.9e-05 25.3 14.7 24 5.7 0.1 8.2 1 1 6 8 8 8 0 C-terminal domain of methyl-CpG binding protein 2 and 3 PT-HINT PF07591.11 OWF56731.1 - 0.00042 20.6 53.5 2.7 8.2 0.5 10.7 1 1 9 10 10 10 7 Pretoxin HINT domain DNase_NucA_NucB PF14040.6 OWF56731.1 - 0.0048 17.3 11.1 1.3e+02 3.0 0.0 7.3 7 0 0 7 7 7 0 Deoxyribonuclease NucA/NucB NosD PF05048.13 OWF56731.1 - 0.04 13.2 61.7 0.92 8.7 6.1 4.1 1 1 5 6 6 6 0 Periplasmic copper-binding protein (NosD) ACI44 PF15270.6 OWF56731.1 - 0.24 11.6 29.0 26 5.1 0.1 8.4 8 0 0 8 8 8 0 Metallo-carboxypeptidase inhibitor zf_CopZ PF18423.1 OWF56731.1 - 3.9 7.5 38.1 1.7e+02 2.3 0.1 13.9 9 5 6 15 15 15 0 Zinc binding domain Hc1 PF07432.13 OWF56731.1 - 6.3 7.2 28.7 14 6.1 0.1 7.7 1 1 7 10 10 10 0 Histone H1-like protein Hc1 MIP PF00230.20 OWF56732.1 - 6.4e-39 134.0 1.4 8.1e-39 133.7 1.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein PilM PF07419.12 OWF56732.1 - 0.099 12.8 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 PilM SLC12 PF03522.15 OWF56733.1 - 1.7e-143 478.7 0.0 2.2e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 OWF56733.1 - 3.9e-116 388.5 34.2 4.7e-116 388.2 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.10 OWF56733.1 - 0.0064 16.0 0.2 0.017 14.6 0.2 1.6 1 0 0 1 1 1 1 Amino acid permease N-terminal Usp PF00582.26 OWF56734.1 - 5e-27 95.1 0.2 6.3e-27 94.8 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family Ntox15 PF15604.6 OWF56734.1 - 0.14 12.3 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Novel toxin 15 Usp PF00582.26 OWF56735.1 - 1.9e-22 80.3 0.1 2.4e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family YejG PF13989.6 OWF56735.1 - 0.012 16.1 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 YejG-like protein Usp PF00582.26 OWF56736.1 - 0.00015 22.3 0.0 0.00017 22.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family NCU-G1 PF15065.6 OWF56738.1 - 2.7e-97 326.0 0.3 3.2e-97 325.8 0.3 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 Insulin_TMD PF17870.1 OWF56738.1 - 0.28 11.3 1.4 0.69 10.0 1.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ion_trans_N PF08412.10 OWF56739.1 - 2.4e-23 81.5 0.4 9.5e-23 79.5 0.4 2.1 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans PF00520.31 OWF56739.1 - 6.2e-23 81.3 14.9 8.8e-23 80.8 14.9 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OWF56739.1 - 7.3e-15 54.8 0.0 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Osw5 PF17062.5 OWF56739.1 - 0.0036 17.4 3.0 0.0087 16.1 3.0 1.6 1 0 0 1 1 1 1 Outer spore wall 5 Ion_trans_2 PF07885.16 OWF56739.1 - 0.009 16.0 0.1 0.023 14.6 0.1 1.7 1 0 0 1 1 1 1 Ion channel Leader_CPA1 PF08252.11 OWF56740.1 - 0.0076 15.6 31.7 33 4.0 0.0 14.2 17 0 0 17 17 17 0 arg-2/CPA1 leader peptide APC_N_CC PF16689.5 OWF56740.1 - 0.012 15.6 5.5 63 3.7 0.3 5.3 3 2 4 7 7 7 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1661 PF07877.11 OWF56740.1 - 0.017 14.8 10.7 2.4e+02 1.5 0.0 9.8 7 2 2 11 11 11 0 Protein of unknown function (DUF1661) EBA-175_VI PF11556.8 OWF56740.1 - 1.1 9.6 15.0 28 5.1 1.6 5.0 3 2 2 5 5 5 0 Erythrocyte binding antigen 175 CTXphi_pIII-N1 PF16710.5 OWF56740.1 - 2 8.5 25.8 82 3.4 0.9 8.8 1 1 6 7 7 7 0 N-terminal N1 domain of Vibrio phage CTXphi pIII ATP-synt_S1 PF05827.12 OWF56740.1 - 3.1 7.6 6.6 50 3.7 0.2 3.3 3 0 0 3 3 3 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Peptidase_S8 PF00082.22 OWF56741.1 - 4.1e-48 164.2 4.8 8.3e-48 163.2 4.8 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OWF56741.1 - 2e-25 88.6 0.4 4.8e-25 87.4 0.4 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OWF56741.1 - 1.3e-20 74.0 1.6 2.5e-20 73.0 1.6 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain DUF3456 PF11938.8 OWF56742.1 - 9.8e-34 117.1 4.1 9.8e-34 117.1 4.1 1.9 2 0 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP DOG1 PF14144.6 OWF56742.1 - 0.027 14.7 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Seed dormancy control SAPS PF04499.15 OWF56742.1 - 0.63 8.7 10.1 0.68 8.6 10.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 OWF56742.1 - 0.9 8.8 17.7 1 8.6 17.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 OWF56742.1 - 2.9 6.1 12.9 4.1 5.6 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M24 PF00557.24 OWF56743.1 - 5.2e-48 163.5 0.0 6.4e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF402 PF04167.13 OWF56744.1 - 0.32 11.2 7.6 6.4 7.1 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF402) Ig_3 PF13927.6 OWF56745.1 - 2.9e-63 210.4 16.6 7.4e-14 52.1 0.3 6.8 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 OWF56745.1 - 3.9e-61 203.1 4.1 2.8e-13 49.7 0.0 7.7 8 0 0 8 8 8 6 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF56745.1 - 2e-43 146.6 12.3 1.3e-11 44.7 0.3 6.9 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 OWF56745.1 - 1.6e-35 121.3 7.1 7.3e-11 42.3 0.0 6.0 5 0 0 5 5 5 5 Fibronectin type III domain ig PF00047.25 OWF56745.1 - 1.8e-34 117.7 9.3 4.7e-10 39.5 0.4 6.5 6 0 0 6 6 6 5 Immunoglobulin domain Bravo_FIGEY PF13882.6 OWF56745.1 - 9.9e-20 71.7 3.0 1.9e-19 70.8 3.0 1.5 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 OWF56745.1 - 1.4e-15 57.4 17.9 0.0072 16.5 1.8 8.9 7 4 3 10 10 9 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 OWF56745.1 - 1.5e-12 47.4 3.0 0.0012 18.9 0.1 5.7 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 OWF56745.1 - 1.2e-08 35.3 0.0 0.72 10.3 0.0 5.4 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 OWF56745.1 - 4.9e-06 26.5 0.5 3.5 7.7 0.0 5.0 4 1 0 4 4 4 2 C17orf99 Ig domain Cadherin_3 PF16184.5 OWF56745.1 - 0.019 15.0 0.0 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Cadherin-like V-set_CD47 PF08204.11 OWF56745.1 - 0.046 13.7 0.6 37 4.3 0.0 4.3 5 0 0 5 5 5 0 CD47 immunoglobulin-like domain Tissue_fac PF01108.17 OWF56745.1 - 0.21 11.4 2.2 12 5.8 0.0 3.9 5 0 0 5 5 5 0 Tissue factor Amidase PF01425.21 OWF56746.1 - 9.6e-112 374.2 0.0 1.3e-111 373.8 0.0 1.1 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.26 OWF56747.1 - 9e-25 87.2 0.0 1.8e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OWF56747.1 - 4.1e-20 73.2 0.0 2.6e-19 70.6 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OWF56747.1 - 4e-13 49.2 0.4 9.5e-13 48.0 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RhoGEF PF00621.20 OWF56748.1 - 1.6e-48 165.3 5.3 2.8e-48 164.6 4.3 2.0 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 OWF56748.1 - 7.9e-19 67.6 13.3 2.3e-18 66.1 13.3 1.9 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 OWF56748.1 - 1.4e-13 51.2 1.6 4.6e-10 40.0 0.1 3.9 4 0 0 4 4 4 2 PH domain AbiJ_NTD4 PF18863.1 OWF56748.1 - 0.064 13.7 1.8 0.11 13.0 0.2 2.2 2 0 0 2 2 2 0 AbiJ N-terminal domain 4 BNR PF02012.20 OWF56748.1 - 0.099 12.7 0.2 0.33 11.1 0.2 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Stress-antifung PF01657.17 OWF56749.1 - 0.13 13.0 2.7 1.1e+02 3.5 2.7 4.4 1 1 0 1 1 1 0 Salt stress response/antifungal GSG-1 PF07803.11 OWF56749.1 - 0.47 10.4 9.2 49 3.9 2.0 4.5 1 1 1 2 2 2 0 GSG1-like protein YccJ PF13993.6 OWF56749.1 - 0.58 10.5 14.5 20 5.6 1.2 4.8 1 1 4 5 5 5 0 YccJ-like protein DUF2654 PF10849.8 OWF56749.1 - 0.63 10.3 6.4 68 3.8 0.4 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF2654) Sec7 PF01369.20 OWF56750.1 - 2.3e-65 219.7 0.3 5.7e-65 218.4 0.3 1.7 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 OWF56750.1 - 2.9e-58 195.7 1.4 2.9e-58 195.7 1.4 2.0 2 0 0 2 2 2 1 PH domain Ig_3 PF13927.6 OWF56751.1 - 8.7e-16 58.3 7.4 2e-11 44.3 0.4 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 OWF56751.1 - 6.6e-11 42.1 1.1 1.7e-08 34.4 0.1 3.3 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.6 OWF56751.1 - 3.7e-09 36.8 10.8 5.6e-07 29.8 0.1 3.7 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 OWF56751.1 - 2.5e-08 34.0 5.7 7.8e-05 22.8 1.0 3.1 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.17 OWF56751.1 - 4.9e-08 33.1 7.2 0.01 16.0 0.6 3.7 2 1 1 3 3 3 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 OWF56751.1 - 0.0038 17.2 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 OWF56751.1 - 0.15 12.3 0.1 2.1 8.6 0.0 2.5 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DUF2802 PF10975.8 OWF56752.1 - 6.3e-13 48.7 2.5 6.8 6.9 0.0 11.3 2 2 8 14 14 14 2 Protein of unknown function (DUF2802) DUF4968 PF16338.5 OWF56752.1 - 6.5e-08 32.8 25.0 57 4.1 0.0 16.6 16 6 7 23 23 23 0 Domain of unknown function (DUF4968) PLCC PF14466.6 OWF56752.1 - 5.4e-07 29.8 37.8 14 5.8 0.1 15.3 3 2 17 21 21 21 1 PLAT/LH2 and C2-like Ca2+-binding lipoprotein DUF573 PF04504.14 OWF56752.1 - 9.7e-06 26.2 58.8 7.2 7.3 0.2 14.1 1 1 13 14 14 14 3 Protein of unknown function, DUF573 ETC_C1_NDUFA5 PF04716.14 OWF56752.1 - 2.2e-05 24.2 4.8 41 4.1 0.0 8.7 8 3 2 10 10 10 0 ETC complex I subunit conserved region DUF4457 PF14652.6 OWF56752.1 - 2.8e-05 23.5 27.3 4.5 6.4 0.1 9.2 2 2 4 9 9 9 4 Domain of unknown function (DUF4457) DUF2973 PF11189.8 OWF56752.1 - 3.7e-05 23.7 20.6 67 3.7 0.3 14.9 16 7 0 17 17 17 0 Protein of unknown function (DUF2973) RHS_repeat PF05593.14 OWF56752.1 - 5.9e-05 23.5 64.5 26 5.5 0.5 21.3 8 5 19 27 27 27 0 RHS Repeat Cecropin PF00272.19 OWF56752.1 - 9.7e-05 22.0 16.5 6.7 6.5 0.0 6.2 6 0 0 6 6 6 5 Cecropin family MADF_DNA_bdg PF10545.9 OWF56752.1 - 0.04 14.2 35.7 3.3 8.1 0.9 9.8 5 3 6 11 11 11 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ig_3 PF13927.6 OWF56753.1 - 4e-14 53.0 13.4 1.4e-11 44.8 0.7 4.4 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 OWF56753.1 - 1.1e-10 41.4 3.5 2.6e-09 37.0 0.1 3.7 4 0 0 4 4 4 1 Immunoglobulin I-set domain fn3 PF00041.21 OWF56753.1 - 1.9e-10 41.0 0.5 1.9e-10 41.0 0.5 3.2 3 0 0 3 3 3 1 Fibronectin type III domain ig PF00047.25 OWF56753.1 - 7.6e-08 32.4 10.4 6.1e-06 26.3 1.1 3.7 3 1 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 OWF56753.1 - 3e-07 30.7 9.7 4.7e-06 26.8 0.2 4.0 3 1 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 OWF56753.1 - 6.2e-07 29.6 8.2 0.0015 18.6 0.7 4.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain Big_10 PF17964.1 OWF56753.1 - 0.0043 17.1 0.2 0.013 15.5 0.2 1.8 1 0 0 1 1 1 1 Bacterial Ig domain Izumo-Ig PF16706.5 OWF56753.1 - 0.0061 16.6 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain DUF2369 PF10179.9 OWF56753.1 - 0.015 15.7 0.8 0.04 14.3 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Protocadherin PF08374.11 OWF56753.1 - 0.061 13.3 2.7 0.098 12.6 0.0 2.2 2 0 0 2 2 2 0 Protocadherin DUF4596 PF15363.6 OWF56754.1 - 9.4e-06 25.8 6.8 22 5.4 0.0 7.0 5 1 3 8 8 8 4 Domain of unknown function (DUF4596) HSP20 PF00011.21 OWF56756.1 - 2.5e-30 104.6 0.3 2.9e-14 53.1 0.1 2.6 2 1 1 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OWF56756.1 - 1e-07 31.4 0.2 0.0012 18.3 0.1 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA PSS PF03034.15 OWF56757.1 - 3.5e-114 381.2 12.8 3.5e-114 381.2 12.8 1.7 2 0 0 2 2 2 1 Phosphatidyl serine synthase 7TMR-DISM_7TM PF07695.11 OWF56757.1 - 0.0022 17.9 0.2 0.0022 17.9 0.2 3.0 3 0 0 3 3 3 2 7TM diverse intracellular signalling DUF998 PF06197.13 OWF56757.1 - 0.025 14.2 1.8 0.058 13.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF998) DUF3382 PF11862.8 OWF56757.1 - 0.057 13.7 0.0 0.057 13.7 0.0 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) TctB PF07331.11 OWF56757.1 - 0.071 13.4 0.1 0.071 13.4 0.1 3.2 3 1 1 4 4 4 0 Tripartite tricarboxylate transporter TctB family C2 PF00168.30 OWF56758.1 - 3.8e-17 62.5 0.0 1.3e-16 60.7 0.0 2.0 1 0 0 1 1 1 1 C2 domain RBD-FIP PF09457.10 OWF56758.1 - 7e-10 38.7 1.4 1.2e-09 37.9 1.4 1.4 1 0 0 1 1 1 1 FIP domain PMP22_Claudin PF00822.20 OWF56759.1 - 4.5e-07 29.9 8.6 5.5e-07 29.6 8.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 OWF56759.1 - 5.1e-06 26.8 2.6 5.1e-06 26.8 2.6 1.5 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 OWF56759.1 - 0.002 17.9 18.8 0.11 12.2 0.0 2.6 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 OWF56759.1 - 0.0048 16.9 10.1 0.0089 16.0 10.1 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 OWF56759.1 - 0.036 13.9 9.0 0.03 14.2 8.0 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_3 PF06653.11 OWF56760.1 - 1e-05 25.6 11.4 0.00011 22.2 11.4 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 OWF56760.1 - 0.00026 20.9 3.8 0.00032 20.6 3.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 OWF56760.1 - 0.00041 20.2 19.3 0.1 12.4 14.9 2.6 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 OWF56761.1 - 2.4e-09 37.3 10.0 3e-09 37.0 10.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 OWF56761.1 - 8.8e-06 25.6 19.0 0.0042 16.9 0.2 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 OWF56761.1 - 0.00013 21.8 7.3 0.00017 21.4 7.3 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_3 PF06653.11 OWF56761.1 - 0.0022 18.0 11.1 0.01 15.8 11.1 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like TMEM252 PF15664.5 OWF56761.1 - 0.092 12.5 0.4 0.23 11.2 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 252 family DEAD PF00270.29 OWF56762.1 - 4.1e-14 52.7 0.0 5.9e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OWF56762.1 - 1.6e-05 25.2 0.0 0.00043 20.6 0.1 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Lipoprotein_17 PF04200.12 OWF56764.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.6 2 1 1 3 3 3 0 Lipoprotein associated domain TSP_1 PF00090.19 OWF56765.1 - 4.5e-57 190.1 92.0 2e-09 37.5 6.3 9.4 8 0 0 8 8 8 8 Thrombospondin type 1 domain Gal_Lectin PF02140.18 OWF56765.1 - 5.5e-18 65.2 44.9 0.0015 18.9 1.4 9.3 8 1 0 8 8 8 6 Galactose binding lectin domain EGF PF00008.27 OWF56765.1 - 2.5e-06 27.7 75.4 0.002 18.4 4.3 7.6 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.7 OWF56765.1 - 0.18 12.5 67.6 0.59 10.8 2.9 9.3 7 0 0 7 7 7 0 Human growth factor-like EGF RRM_3 PF08777.11 OWF56765.1 - 0.29 11.2 4.5 34 4.5 0.0 4.9 5 0 0 5 5 5 0 RNA binding motif Gp58 PF07902.11 OWF56766.1 - 0.013 13.9 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 0 gp58-like protein MDM31_MDM32 PF08118.11 OWF56766.1 - 2.4 6.7 9.5 7.6 5.1 0.2 4.0 1 1 2 4 4 4 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF3231 PF11553.8 OWF56766.1 - 7.2 6.2 8.2 45 3.6 0.1 4.2 2 2 3 5 5 5 0 Protein of unknown function (DUF3231) HLH PF00010.26 OWF56768.1 - 1.2e-15 57.2 4.5 2.3e-15 56.3 4.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF56768.1 - 1.6e-12 47.4 0.0 2.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Hairy Orange MRP-L28 PF09812.9 OWF56768.1 - 0.0085 16.2 0.1 0.0085 16.2 0.1 2.2 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L28 HLH PF00010.26 OWF56769.1 - 2.4e-16 59.4 3.6 4.7e-16 58.5 3.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 OWF56769.1 - 1e-12 48.0 0.0 2.5e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Hairy Orange Methyltransf_FA PF12248.8 OWF56770.1 - 5e-16 58.9 0.0 9.2e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase PAN_1 PF00024.26 OWF56770.1 - 2.3e-06 27.4 0.6 5.2e-06 26.3 0.6 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OWF56770.1 - 2.9e-05 23.9 1.0 9.2e-05 22.3 1.0 1.9 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 OWF56770.1 - 0.00096 19.2 0.5 0.0021 18.1 0.5 1.6 1 0 0 1 1 1 1 PAN-like domain PAN_3 PF08277.12 OWF56770.1 - 0.047 13.5 0.5 0.09 12.6 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain UDPG_MGDP_dh PF00984.19 OWF56770.1 - 0.16 12.2 0.0 2.3 8.5 0.0 2.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Transglut_core PF01841.19 OWF56771.1 - 8.1e-05 23.1 0.1 0.00019 21.8 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily MT PF12777.7 OWF56771.1 - 0.018 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor SCO1-SenC PF02630.14 OWF56773.1 - 1.8e-43 147.7 0.0 2.7e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OWF56773.1 - 0.00015 21.7 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OWF56773.1 - 0.0056 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Cupin_8 PF13621.6 OWF56774.1 - 1.1e-25 90.8 0.1 2.7e-25 89.5 0.1 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OWF56774.1 - 1.8e-09 38.0 0.3 6.4e-09 36.2 0.0 2.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase 7tm_1 PF00001.21 OWF56775.1 - 7.4e-31 107.4 24.8 9.7e-31 107.0 24.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 OWF56775.1 - 8.6e-14 51.8 24.5 1.1e-13 51.4 24.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 OWF56775.1 - 1.5e-07 31.1 23.4 1.9e-07 30.7 23.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 OWF56775.1 - 0.0057 16.4 20.5 0.015 15.1 20.5 1.7 1 1 0 1 1 1 1 Olfactory receptor Spo7 PF03907.13 OWF56775.1 - 0.62 9.5 3.1 7.2 6.0 0.1 2.4 2 0 0 2 2 2 0 Spo7-like protein Acyl_transf_3 PF01757.22 OWF56776.1 - 2.7e-24 85.9 32.1 4.9e-24 85.0 32.1 1.3 1 0 0 1 1 1 1 Acyltransferase family TB2_DP1_HVA22 PF03134.19 OWF56776.1 - 0.013 15.4 2.4 0.013 15.4 2.4 2.7 2 0 0 2 2 2 0 TB2/DP1, HVA22 family DUF4370 PF14290.6 OWF56776.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) Mucin-like PF16058.5 OWF56777.1 - 4.4e-26 90.9 128.6 0.0035 17.4 8.8 11.0 3 2 3 8 8 8 7 Mucin-like 2-oxogl_dehyd_N PF16078.5 OWF56779.1 - 0.0023 17.5 2.6 24 4.6 0.0 5.3 6 2 0 6 6 6 3 2-oxoglutarate dehydrogenase N-terminus RTC4 PF14474.6 OWF56780.1 - 0.074 13.2 1.9 5.1 7.3 1.9 2.8 1 1 0 1 1 1 0 RTC4-like domain Macoilin PF09726.9 OWF56780.1 - 0.16 10.5 7.3 0.15 10.6 7.3 1.2 1 0 0 1 1 1 0 Macoilin family Sec3_C PF09763.9 OWF56780.1 - 1 7.7 6.8 1.1 7.6 6.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Ring_hydroxyl_A PF00848.19 OWF56780.1 - 4.6 7.1 10.8 1.2e+02 2.5 3.7 3.3 1 1 1 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) HC2 PF07382.11 OWF56781.1 - 8.5e-07 29.2 28.3 0.00092 19.3 12.6 2.1 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 HC2 PF07382.11 OWF56782.1 - 0.0045 17.1 8.0 0.0053 16.9 8.0 1.0 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Desmo_N PF06771.11 OWF56783.1 - 0.042 14.2 5.1 22 5.5 1.6 4.4 1 1 1 3 3 3 0 Viral Desmoplakin N-terminus DUF3791 PF12668.7 OWF56783.1 - 0.53 10.4 18.6 26 5.0 0.1 7.4 1 1 6 9 9 9 0 Protein of unknown function (DUF3791) Cmc1 PF08583.10 OWF56783.1 - 5 7.2 18.9 3 7.9 1.0 5.4 2 2 4 6 6 6 0 Cytochrome c oxidase biogenesis protein Cmc1 like NNMT_PNMT_TEMT PF01234.17 OWF56784.1 - 4.8e-56 189.8 0.7 5.6e-55 186.3 0.7 1.9 1 1 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 OWF56784.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OWF56784.1 - 0.0053 17.4 0.0 0.13 12.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OWF56784.1 - 0.018 15.8 0.0 0.048 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OWF56784.1 - 0.024 14.0 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OWF56784.1 - 0.054 13.3 0.1 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 OWF56784.1 - 0.065 14.0 0.0 4.6 8.0 0.0 2.4 1 1 0 2 2 2 0 Methyltransferase domain SLATT_5 PF18160.1 OWF56785.1 - 4.3 6.6 12.4 3.4 7.0 8.7 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Glyco_transf_7N PF13733.6 OWF56786.1 - 2.9e-51 172.6 0.1 4.2e-51 172.1 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 OWF56786.1 - 6.1e-25 86.7 0.1 1.4e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Bcr-Abl_Oligo PF09036.10 OWF56786.1 - 0.15 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Mucin-like PF16058.5 OWF56788.1 - 2.6e-06 27.4 0.0 0.024 14.7 0.0 3.2 1 1 1 3 3 3 3 Mucin-like Ints3 PF10189.9 OWF56788.1 - 0.0012 18.1 7.3 17 4.6 0.1 5.3 1 1 5 6 6 6 3 Integrator complex subunit 3 SSXT PF05030.12 OWF56788.1 - 0.21 11.2 4.9 42 3.9 0.0 5.0 5 2 0 6 6 6 0 SSXT protein (N-terminal region) Soyouz_module PF14313.6 OWF56788.1 - 0.27 11.0 15.7 16 5.4 0.3 6.6 3 2 4 8 8 8 0 N-terminal region of Paramyxovirinae phosphoprotein (P) TC1 PF15063.6 OWF56789.1 - 1.3e-05 25.0 0.0 0.062 13.2 0.0 2.2 2 0 0 2 2 2 2 Thyroid cancer protein 1 GST_C_3 PF14497.6 OWF56790.1 - 4.3e-18 65.3 0.1 6.3e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF56790.1 - 7.7e-10 39.0 0.0 2.4e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF56790.1 - 4e-06 27.0 0.1 6.5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OWF56790.1 - 0.0038 17.0 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OWF56790.1 - 0.15 12.8 0.0 0.35 11.6 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 OWF56791.1 - 3.4e-20 72.1 0.0 4.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OWF56791.1 - 2.9e-08 34.0 0.0 5.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OWF56791.1 - 2.5e-06 27.6 0.1 2.7e-05 24.3 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OWF56791.1 - 9.9e-05 22.7 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 OWF56791.1 - 0.036 14.4 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N PF02798.20 OWF56792.1 - 9.2e-11 41.9 0.0 1.9e-10 40.9 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OWF56792.1 - 2.3e-08 34.3 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OWF56792.1 - 8.2e-08 32.4 0.1 2.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OWF56792.1 - 0.00071 20.3 0.0 0.001 19.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OWF56792.1 - 0.0074 16.6 0.0 0.0092 16.3 0.0 1.4 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF4351 PF14261.6 OWF56792.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Lectin_C PF00059.21 OWF56793.1 - 2e-08 34.9 0.1 2e-08 34.9 0.1 1.7 2 0 0 2 2 2 1 Lectin C-type domain PAN_4 PF14295.6 OWF56793.1 - 2.2 8.3 8.8 9.6 6.2 6.3 2.8 2 1 0 2 2 2 0 PAN domain LPMO_10 PF03067.15 OWF56794.1 - 3.6e-35 122.4 2.0 3.6e-35 122.4 2.0 2.3 3 0 0 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Rnf-Nqr PF02508.14 OWF56795.1 - 0.92 9.5 42.0 0.25 11.3 4.0 4.8 1 1 3 4 4 4 0 Rnf-Nqr subunit, membrane protein HlyD PF00529.20 OWF56795.1 - 3.2 7.7 14.3 12 5.8 0.8 4.4 3 1 1 4 4 4 0 HlyD membrane-fusion protein of T1SS MspA PF09203.11 OWF56795.1 - 4.9 7.0 33.7 1.5 8.7 5.1 3.6 1 1 2 3 3 3 0 MspA PBP PF01161.20 OWF56796.1 - 4.7e-18 65.8 3.8 5.8e-11 42.8 0.2 3.3 2 1 1 3 3 3 2 Phosphatidylethanolamine-binding protein Ion_trans PF00520.31 OWF56797.1 - 3.7e-20 72.2 16.4 5.6e-20 71.6 16.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OWF56797.1 - 2.5e-10 40.2 7.1 2.5e-10 40.2 7.1 2.6 2 0 0 2 2 2 1 Ion channel BTB_2 PF02214.22 OWF56797.1 - 4.3e-10 39.8 0.0 9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Trp_oprn_chp PF09534.10 OWF56797.1 - 0.28 11.0 3.7 3.4 7.4 3.7 2.2 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) zf-LITAF-like PF10601.9 OWF56797.1 - 0.59 10.4 2.8 4.1 7.8 0.4 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain RWD PF05773.22 OWF56798.1 - 8.7e-20 71.1 0.2 2.4e-19 69.7 0.2 1.8 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 OWF56798.1 - 1.2e-06 28.7 7.4 5.2e-06 26.7 7.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF56798.1 - 1.5e-05 24.6 6.6 3.9e-05 23.3 6.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OWF56798.1 - 0.00023 21.1 7.2 0.00056 19.8 7.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OWF56798.1 - 0.00073 19.5 6.5 0.0037 17.3 3.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF56798.1 - 0.001 18.9 3.3 0.001 18.9 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OWF56798.1 - 0.016 15.0 4.4 0.085 12.7 4.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OWF56798.1 - 0.58 10.2 5.4 2 8.5 2.7 2.5 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2175 PF09943.9 OWF56798.1 - 0.61 10.4 2.8 1.8 8.9 2.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RING-like PF08746.11 OWF56798.1 - 4.1 7.8 7.9 1 9.7 3.9 2.1 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.6 OWF56799.1 - 9.4e-07 29.1 6.2 1.6e-06 28.3 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OWF56799.1 - 1.9e-06 27.5 6.1 3.9e-06 26.5 6.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OWF56799.1 - 6e-05 23.0 2.9 0.00011 22.2 2.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OWF56799.1 - 8.3e-05 22.4 2.4 8.3e-05 22.4 2.4 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OWF56799.1 - 0.001 19.0 7.3 0.0015 18.5 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain RWD PF05773.22 OWF56799.1 - 0.0021 18.4 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 OWF56799.1 - 0.0026 17.6 2.8 0.0026 17.6 2.8 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OWF56799.1 - 0.035 14.4 3.5 0.059 13.7 3.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 OWF56799.1 - 0.15 12.3 6.6 0.88 9.9 6.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OWF56799.1 - 0.21 11.7 3.8 0.41 10.7 3.8 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2175 PF09943.9 OWF56799.1 - 0.26 11.6 4.1 0.19 12.1 2.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) IL17 PF06083.11 OWF56800.1 - 7.5e-16 58.4 6.4 1.6e-15 57.4 6.4 1.6 1 0 0 1 1 1 1 Interleukin-17 LRV PF01816.17 OWF56802.1 - 4.3e-07 29.9 14.1 4.6e+02 1.6 0.0 19.2 30 0 0 30 30 30 0 Leucine rich repeat variant Glyco_transf_21 PF13506.6 OWF56802.1 - 0.00017 21.1 15.1 32 3.9 0.1 11.7 4 3 8 16 16 16 0 Glycosyl transferase family 21 Longin PF13774.6 OWF56802.1 - 0.0021 18.0 4.1 2.1e+02 2.0 0.0 8.8 8 2 1 9 9 9 0 Regulated-SNARE-like domain PORR PF11955.8 OWF56802.1 - 0.0076 15.2 1.0 58 2.5 0.0 5.7 5 1 1 7 7 7 0 Plant organelle RNA recognition domain RNA_pol_Rbc25 PF08292.12 OWF56802.1 - 0.011 15.9 30.7 35 4.6 0.4 13.7 10 7 5 17 17 17 0 RNA polymerase III subunit Rpc25 SCAN PF02023.17 OWF56802.1 - 0.12 12.1 1.2 20 5.1 0.0 4.7 4 1 1 6 6 6 0 SCAN domain DnaJ PF00226.31 OWF56803.1 - 5.6e-20 71.2 0.6 1e-19 70.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain NatB_MDM20 PF09797.9 OWF56804.1 - 4.6e-97 325.4 4.2 9.7e-97 324.3 4.2 1.6 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit NARP1 PF12569.8 OWF56804.1 - 5.1e-06 25.7 2.6 0.00092 18.2 0.0 2.6 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 OWF56804.1 - 9.6e-06 26.0 2.4 0.0045 17.7 0.2 4.9 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OWF56804.1 - 1.6e-05 25.3 6.2 0.15 12.6 1.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 OWF56804.1 - 0.00086 19.8 0.3 0.56 10.6 0.2 3.6 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 OWF56804.1 - 0.0047 17.6 0.4 0.023 15.3 0.0 2.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OWF56804.1 - 0.13 12.4 9.3 17 5.8 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3106 PF11304.8 OWF56804.1 - 0.13 12.7 2.0 45 4.6 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) ANAPC3 PF12895.7 OWF56804.1 - 1.1 9.6 6.0 1.3 9.3 0.4 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4291 PF14124.6 OWF56805.1 - 1.8e-62 210.4 1.5 2.4e-62 210.0 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) zf-Tim10_DDP PF02953.15 OWF56806.1 - 4.8e-18 64.6 0.9 4.8e-18 64.6 0.9 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF842 PF05811.13 OWF56806.1 - 0.0015 18.2 5.0 0.0018 17.9 5.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-C2HC_2 PF13913.6 OWF56807.1 - 0.0021 17.9 10.1 0.46 10.5 0.6 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type XAF1_C PF18608.1 OWF56807.1 - 0.0036 16.8 5.1 0.0081 15.7 0.1 2.9 3 0 0 3 3 3 1 XIAP-associated factor 1 C-terminal domain zf-FCS PF06467.14 OWF56807.1 - 0.42 10.6 2.4 18 5.4 0.6 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF1178 PF06676.11 OWF56807.1 - 1.6 9.2 6.3 0.94 9.9 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf_UBZ PF18439.1 OWF56807.1 - 2.1 8.0 9.5 2.9 7.5 0.6 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger MAPEG PF01124.18 OWF56808.1 - 2.3e-06 27.6 0.1 2.6e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 MAPEG family DUF2711 PF10924.8 OWF56808.1 - 0.04 13.5 0.0 0.041 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) zf-H2C2_2 PF13465.6 OWF56809.1 - 3.8e-60 197.8 72.6 3.8e-07 30.2 1.1 13.7 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 OWF56809.1 - 3.6e-42 139.4 84.4 0.0015 19.2 1.1 13.6 13 0 0 13 13 13 13 C2H2-type zinc finger zf-C2H2 PF00096.26 OWF56809.1 - 1.5e-41 138.6 91.2 8.7e-06 25.9 3.0 13.6 13 0 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OWF56809.1 - 3.3e-17 62.0 75.7 0.00017 21.5 0.6 12.9 13 0 0 13 13 13 8 C2H2-type zinc finger zf-met PF12874.7 OWF56809.1 - 9.4e-11 41.7 65.5 0.008 16.5 0.0 13.3 14 1 0 14 14 14 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OWF56809.1 - 4.3e-10 39.6 58.5 0.53 10.6 0.0 13.4 14 0 0 14 14 14 5 Zinc-finger double-stranded RNA-binding BolA PF01722.18 OWF56809.1 - 9.7e-05 22.6 15.7 0.21 11.9 0.4 6.1 5 2 1 6 6 6 2 BolA-like protein Zn-ribbon_8 PF09723.10 OWF56809.1 - 0.0015 18.6 51.4 0.33 11.1 2.1 9.2 7 4 2 9 9 9 3 Zinc ribbon domain ADK_lid PF05191.14 OWF56809.1 - 0.0024 17.8 45.1 0.013 15.5 0.8 8.7 6 2 1 7 7 7 3 Adenylate kinase, active site lid zf_UBZ PF18439.1 OWF56809.1 - 0.0043 16.6 46.3 7.6 6.2 0.6 11.8 12 0 0 12 12 12 2 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 OWF56809.1 - 0.015 15.6 2.1 0.015 15.6 2.1 6.6 2 1 6 8 8 8 0 C2H2-type zinc ribbon zf-C4_Topoisom PF01396.19 OWF56809.1 - 0.031 14.1 17.0 2.7 7.8 0.1 6.9 6 0 0 6 6 6 0 Topoisomerase DNA binding C4 zinc finger MIP-T3_C PF17749.1 OWF56809.1 - 0.049 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF5318 PF17249.2 OWF56809.1 - 0.62 9.8 6.4 0.28 11.0 0.2 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5318) zinc_ribbon_15 PF17032.5 OWF56809.1 - 7 7.5 53.1 0.15 12.8 2.5 7.1 6 1 2 8 8 7 0 zinc-ribbon family Ras PF00071.22 OWF56810.1 - 5.7e-41 139.8 0.1 1.1e-40 138.8 0.1 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OWF56810.1 - 4e-25 88.4 0.0 7.7e-25 87.4 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OWF56810.1 - 1.1e-06 28.2 0.0 4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OWF56810.1 - 6.1e-06 25.9 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OWF56810.1 - 0.05 13.7 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 OWF56810.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 OWF56810.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OWF56810.1 - 0.15 12.0 0.1 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DJ-1_PfpI PF01965.24 OWF56811.1 - 7.4e-16 58.4 0.0 7.8e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family PALP PF00291.25 OWF56812.1 - 4.6e-65 219.9 0.3 5.4e-65 219.7 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AIRC PF00731.20 OWF56812.1 - 0.084 12.4 2.8 4 7.0 0.6 2.3 2 0 0 2 2 2 0 AIR carboxylase DUF4041 PF13250.6 OWF56813.1 - 4.6e-15 55.2 50.6 42 4.1 0.0 19.0 2 1 35 37 37 37 0 Domain of unknown function (DUF4041) DUF5492 PF17596.2 OWF56813.1 - 2.4e-10 40.6 123.3 5.8 7.3 0.7 19.3 1 1 24 25 25 25 21 Family of unknown function (DUF5492) RPT PF13446.6 OWF56813.1 - 3.1e-08 33.4 57.0 76 3.3 0.0 24.3 3 2 15 18 18 18 0 A repeated domain in UCH-protein PCC_BT PF18140.1 OWF56813.1 - 4.9e-08 33.4 38.0 2.7 8.4 2.5 7.7 1 1 6 7 7 7 6 Propionyl-coenzyme A carboxylase BT domain DUF5470 PF17564.2 OWF56813.1 - 2.5e-06 27.6 99.8 1.8 8.8 0.7 13.7 1 1 25 26 26 26 25 Family of unknown function (DUF5470) DbpA PF03880.15 OWF56813.1 - 3e-06 27.1 63.1 20 5.3 0.1 18.5 1 1 33 34 34 34 1 DbpA RNA binding domain DUF1542 PF07564.11 OWF56813.1 - 5.7e-05 23.1 70.1 13 6.0 1.0 13.2 1 1 21 22 22 22 20 Domain of Unknown Function (DUF1542) DnaJ_C PF01556.18 OWF56813.1 - 0.32 11.1 10.1 1.3e+04 -3.9 10.1 6.3 1 1 0 1 1 1 0 DnaJ C terminal domain MFS_1 PF07690.16 OWF56814.1 - 1.5e-09 37.3 27.9 8.8e-06 24.9 7.5 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 OWF56814.1 - 3e-07 30.3 14.1 3e-07 30.3 14.1 3.5 3 2 0 3 3 3 1 Ion channel regulatory protein UNC-93 Ilm1 PF10311.9 OWF56814.1 - 0.029 14.0 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF3335 PF11814.8 OWF56814.1 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase_C39 like family NUDIX PF00293.28 OWF56815.1 - 1.2e-08 35.0 0.2 3.7e-08 33.5 0.2 1.7 1 1 0 1 1 1 1 NUDIX domain DUF4062 PF13271.6 OWF56816.1 - 2.5e-05 24.5 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) CAP_N PF01213.19 OWF56816.1 - 0.0047 16.5 7.8 0.0066 16.0 7.8 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 OWF56816.1 - 1.5 8.8 11.8 2.8 8.0 11.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 OWF56816.1 - 6.8 6.7 16.0 15 5.6 14.6 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator NACHT PF05729.12 OWF56817.1 - 8.2e-14 51.9 0.1 3.2e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OWF56817.1 - 6.8e-11 42.9 0.0 2.5e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain WD40 PF00400.32 OWF56817.1 - 3.1e-09 37.3 10.3 0.0056 17.5 0.0 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat AAA_22 PF13401.6 OWF56817.1 - 1.1e-07 32.1 0.0 3.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OWF56817.1 - 1.8e-06 28.1 0.0 1.8e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea APAF1_C PF17908.1 OWF56817.1 - 1.4e-05 25.2 0.6 4.7e-05 23.4 0.6 1.9 1 0 0 1 1 1 1 APAF-1 helical domain TniB PF05621.11 OWF56817.1 - 0.0017 17.8 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA PF00004.29 OWF56817.1 - 0.013 15.9 0.0 0.038 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nup160 PF11715.8 OWF56817.1 - 0.04 12.5 2.9 2.9 6.4 0.1 3.6 4 0 0 4 4 4 0 Nucleoporin Nup120/160 NB-ARC PF00931.22 OWF56817.1 - 0.068 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain p450 PF00067.22 OWF56818.1 - 1.3e-104 350.6 0.0 1.4e-104 350.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OWF56819.1 - 6.5e-108 361.4 0.0 8.2e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRAM_LAG1_CLN8 PF03798.16 OWF56819.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 TLC domain Peptidase_M76 PF09768.9 OWF56819.1 - 0.16 11.7 0.4 0.28 10.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase M76 family Methyltransf_33 PF10017.9 OWF56820.1 - 2.5e-56 191.1 0.1 2.8e-56 190.9 0.1 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 OWF56820.1 - 0.0053 17.4 0.0 0.017 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MitMem_reg PF13012.6 OWF56821.1 - 4.1e-32 110.9 0.0 6.9e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OWF56821.1 - 1.1e-23 83.4 0.5 3e-23 82.0 0.2 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SSF PF00474.17 OWF56822.1 - 3.6e-44 151.2 26.4 4.8e-44 150.8 26.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family RAMP4 PF06624.12 OWF56822.1 - 5.3 7.2 6.8 0.42 10.7 0.7 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Galactosyl_T PF01762.21 OWF56823.1 - 3.7e-43 147.6 0.5 6.6e-43 146.8 0.5 1.4 1 0 0 1 1 1 1 Galactosyltransferase BLYB PF05289.11 OWF56824.1 - 0.0044 17.2 4.2 0.64 10.2 0.9 2.7 1 1 1 2 2 2 2 Borrelia hemolysin accessory protein TrbL PF04610.14 OWF56824.1 - 0.013 15.3 12.8 0.22 11.2 5.3 2.0 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein TMEM239 PF15841.5 OWF56824.1 - 0.013 15.4 1.0 2.5 8.0 0.1 2.0 1 1 1 2 2 2 0 Transmembrane protein 239 family Phage_rep_O PF04492.13 OWF56824.1 - 0.029 15.0 1.1 6.1 7.5 0.4 2.7 1 1 1 2 2 2 0 Bacteriophage replication protein O MMS19_C PF12460.8 OWF56824.1 - 0.11 11.6 0.7 0.14 11.3 0.7 1.3 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal BLM10_mid PF16507.5 OWF56824.1 - 0.17 10.5 5.7 0.24 10.0 5.7 1.3 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region GED PF02212.18 OWF56824.1 - 0.32 11.2 6.1 0.65 10.2 1.3 2.1 1 1 1 2 2 2 0 Dynamin GTPase effector domain ATC_hydrolase PF14196.6 OWF56824.1 - 0.37 11.6 9.1 1.6 9.5 3.0 2.1 1 1 1 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase MBOAT_2 PF13813.6 OWF56824.1 - 0.4 11.0 6.4 4.7 7.5 6.4 2.2 1 1 0 1 1 1 0 Membrane bound O-acyl transferase family Fas_alpha_ACP PF18325.1 OWF56824.1 - 1.9 8.8 4.8 14 6.0 1.1 2.2 1 1 1 2 2 2 0 Fatty acid synthase subunit alpha Acyl carrier domain Myosin_head PF00063.21 OWF56826.1 - 1.7e-243 809.8 5.5 2.3e-243 809.4 5.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 OWF56826.1 - 7.8e-63 209.7 0.6 7.6e-31 106.8 0.0 3.2 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 OWF56826.1 - 6e-22 78.3 0.0 3.3e-14 53.3 0.0 3.9 3 0 0 3 3 3 2 FERM central domain IQ PF00612.27 OWF56826.1 - 2.4e-09 36.2 28.8 0.0033 17.1 1.9 5.4 5 0 0 5 5 5 4 IQ calmodulin-binding motif FERM_N PF09379.10 OWF56826.1 - 6.3e-09 35.7 1.9 0.012 15.6 0.0 3.9 3 0 0 3 3 3 2 FERM N-terminal domain SH3_9 PF14604.6 OWF56826.1 - 1.9e-05 24.4 0.4 0.00014 21.6 0.0 2.7 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 OWF56826.1 - 6.4e-05 22.6 0.0 0.00016 21.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 OWF56826.1 - 0.00018 21.6 2.5 0.036 14.1 0.0 3.1 3 0 0 3 3 3 2 Phosphotyrosine interaction domain (PTB/PID) SH3_1 PF00018.28 OWF56826.1 - 0.00029 20.4 0.2 0.0047 16.5 0.0 2.7 2 0 0 2 2 2 1 SH3 domain AAA_22 PF13401.6 OWF56826.1 - 0.0025 18.1 0.0 0.099 12.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain RA PF00788.23 OWF56826.1 - 0.0056 17.3 0.0 6.9 7.4 0.0 3.5 3 0 0 3 3 2 1 Ras association (RalGDS/AF-6) domain AAA_16 PF13191.6 OWF56826.1 - 0.088 13.2 0.1 0.43 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF720 PF05302.11 OWF56826.1 - 0.15 11.9 0.2 0.39 10.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF720) ABC_tran PF00005.27 OWF56826.1 - 0.79 10.2 5.8 0.13 12.7 0.4 2.6 2 1 0 2 2 2 0 ABC transporter DUF885 PF05960.11 OWF56827.1 - 5.5e-98 329.9 0.0 6.7e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Propep_M14 PF02244.16 OWF56827.1 - 0.092 13.1 0.0 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase activation peptide VraX PF17412.2 OWF56827.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function Galactosyl_T PF01762.21 OWF56829.1 - 2e-39 135.4 0.1 3.9e-39 134.5 0.0 1.4 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 OWF56829.1 - 0.072 12.5 0.1 0.15 11.5 0.1 1.6 1 1 0 1 1 1 0 Fringe-like HtrL_YibB PF09612.10 OWF56830.1 - 5.2e-18 65.5 2.7 7.4e-18 65.0 2.7 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) DUF3410 PF11890.8 OWF56831.1 - 0.18 11.6 12.5 0.74 9.6 1.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3410) LRR_adjacent PF08191.11 OWF56831.1 - 0.28 11.4 2.9 13 6.1 0.0 3.0 1 1 2 3 3 3 0 LRR adjacent KKLCAg1 PF15204.6 OWF56832.1 - 0.0075 16.3 3.5 23 5.2 1.1 4.8 1 1 2 3 3 3 2 Kita-kyushu lung cancer antigen 1 Peptidase_C2 PF00648.21 OWF56833.1 - 4.7e-111 370.5 0.0 7.6e-111 369.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OWF56833.1 - 7.8e-44 149.4 0.3 1.6e-43 148.4 0.3 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_8 PF13833.6 OWF56833.1 - 5.2e-09 35.8 0.1 0.00014 21.6 0.0 4.1 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 OWF56833.1 - 3.6e-08 32.4 0.1 0.016 14.7 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OWF56833.1 - 1.1e-07 31.2 1.2 0.0074 16.1 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OWF56833.1 - 4.2e-06 26.0 0.7 0.00075 18.9 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 OWF56833.1 - 7.2e-05 23.2 0.9 0.32 11.5 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EMP24_GP25L PF01105.24 OWF56834.1 - 4.1e-33 114.9 0.3 4.7e-33 114.6 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rad4 PF03835.15 OWF56834.1 - 0.13 11.9 0.2 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain NAD_binding_2 PF03446.15 OWF56834.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 7tm_1 PF00001.21 OWF56836.1 - 2.6e-27 95.8 17.4 3.5e-27 95.4 17.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3328 PF11807.8 OWF56836.1 - 0.084 12.6 0.2 0.31 10.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) VMA21 PF09446.10 OWF56836.1 - 8.1 6.6 9.4 0.53 10.4 0.4 3.1 3 1 0 3 3 3 0 VMA21-like domain zf-AN1 PF01428.16 OWF56837.1 - 3.2e-07 30.4 8.5 3.2e-07 30.4 8.5 2.3 3 0 0 3 3 3 1 AN1-like Zinc finger zf-A20 PF01754.16 OWF56837.1 - 4.4e-06 26.5 4.9 1.6e-05 24.7 4.9 2.1 1 0 0 1 1 1 1 A20-like zinc finger ISPD_C PF18706.1 OWF56837.1 - 0.1 12.2 0.9 0.16 11.6 0.9 1.2 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain SKA1 PF07160.12 OWF56837.1 - 7.6 6.3 16.3 7.6 6.3 6.9 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 FKBP_C PF00254.28 OWF56838.1 - 9.9e-35 118.8 0.0 1.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LSM PF01423.22 OWF56839.1 - 4.7e-18 64.6 0.4 6.5e-18 64.2 0.4 1.2 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.8 OWF56839.1 - 1.6 9.3 7.1 0.38 11.3 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Acetyltransf_1 PF00583.25 OWF56841.1 - 4.8e-07 30.0 0.0 8.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OWF56841.1 - 0.00094 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OWF56841.1 - 0.0041 17.5 0.0 0.0075 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.32 OWF56842.1 - 1.2e-33 114.6 24.5 4.3e-05 24.2 0.1 12.3 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OWF56842.1 - 5e-15 55.6 0.8 2.2e-05 24.6 0.0 6.1 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OWF56842.1 - 0.00047 20.1 0.4 0.014 15.3 0.4 3.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A HSBP1 PF06825.12 OWF56842.1 - 3.3 7.7 6.4 0.31 10.9 0.1 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Eapp_C PF10238.9 OWF56843.1 - 1.1e-48 165.1 4.1 1.1e-48 165.1 4.1 2.4 2 2 0 2 2 2 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.14 OWF56843.1 - 3 8.1 7.9 6.5 7.0 4.9 2.7 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAM163 PF15069.6 OWF56844.1 - 0.039 14.4 1.4 0.064 13.7 1.4 1.4 1 1 0 1 1 1 0 FAM163 family EphA2_TM PF14575.6 OWF56844.1 - 0.18 12.7 0.3 0.29 12.0 0.3 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ank_2 PF12796.7 OWF56845.1 - 2.6e-07 31.1 1.1 6 7.5 0.0 6.2 4 2 2 6 6 6 2 Ankyrin repeats (3 copies) NACHT PF05729.12 OWF56845.1 - 0.0019 18.1 0.2 0.0062 16.5 0.1 2.0 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 OWF56845.1 - 0.0036 16.4 0.1 0.0069 15.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 OWF56845.1 - 0.015 15.7 0.1 0.064 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OWF56845.1 - 0.018 15.3 0.2 0.74 10.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OWF56845.1 - 0.019 14.9 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OWF56845.1 - 0.024 14.6 0.0 0.088 12.7 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase CbiA PF01656.23 OWF56845.1 - 0.024 14.7 0.8 0.12 12.5 0.4 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rtf2 PF04641.12 OWF56845.1 - 0.61 9.4 9.8 1.6 8.1 9.8 1.7 1 0 0 1 1 1 0 Rtf2 RING-finger RP-C_C PF11800.8 OWF56845.1 - 1.5 8.9 9.9 0.19 11.8 5.3 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region Pentapeptide_2 PF01469.18 OWF56846.1 - 1.8e-40 136.6 79.0 3.8e-07 29.9 4.3 10.2 2 1 7 11 11 11 10 Pentapeptide repeats (8 copies) RIG-I_C-RD PF11648.8 OWF56846.1 - 1.1e-16 61.1 8.3 1.8e-16 60.4 8.3 1.4 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.31 OWF56846.1 - 4.8e-15 55.9 0.1 1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LMSTEN PF07988.12 OWF56846.1 - 0.11 12.0 0.4 0.24 10.9 0.4 1.5 1 0 0 1 1 1 0 LMSTEN motif DUF2034 PF10356.9 OWF56846.1 - 7.3 6.0 10.0 23 4.4 0.1 4.3 1 1 1 3 3 3 0 Protein of unknown function (DUF2034) Homeodomain PF00046.29 OWF56848.1 - 0.71 9.8 10.3 9.2 6.2 1.8 3.6 2 0 0 2 2 2 0 Homeodomain VWA_CoxE PF05762.14 OWF56849.1 - 1.8e-05 24.2 0.0 7.5e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein FoP_duplication PF13865.6 OWF56849.1 - 0.13 12.9 4.5 0.32 11.6 4.5 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Sulfate_transp PF00916.20 OWF56850.1 - 1e-120 403.0 18.1 1.5e-120 402.5 18.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OWF56850.1 - 1.6e-28 98.7 0.3 2.7e-28 98.0 0.3 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OWF56850.1 - 4.9 7.6 13.0 0.031 14.7 2.0 2.9 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily Pkinase PF00069.25 OWF56851.1 - 1e-62 211.9 0.5 2.1e-62 210.9 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OWF56851.1 - 1.1e-50 172.4 0.2 1.9e-50 171.6 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OWF56851.1 - 1.9e-05 24.7 0.0 0.015 15.2 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OWF56851.1 - 9.9e-05 21.3 0.0 9.9e-05 21.3 0.0 3.6 3 1 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 OWF56851.1 - 0.00018 21.0 0.6 0.00038 19.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OWF56851.1 - 0.0042 16.5 0.0 0.0092 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TERF2_RBM PF16772.5 OWF56851.1 - 0.015 14.7 0.0 0.051 13.0 0.0 1.9 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif RIO1 PF01163.22 OWF56851.1 - 0.018 14.7 0.1 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 RIO1 family UQ_con PF00179.26 OWF56853.1 - 7.8e-62 207.1 0.1 3.5e-52 175.8 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin-conjugating enzyme RWD PF05773.22 OWF56853.1 - 0.016 15.5 0.7 0.076 13.3 0.0 2.2 2 1 0 2 2 2 0 RWD domain Prok-E2_B PF14461.6 OWF56853.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 OWF56853.1 - 0.11 12.4 0.1 0.42 10.5 0.0 2.0 3 0 0 3 3 3 0 UEV domain GalP_UDP_transf PF01087.22 OWF56853.1 - 0.39 11.1 1.6 5.6 7.4 0.4 2.1 1 1 1 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Ceramidase PF05875.12 OWF56854.1 - 3.3e-66 223.4 23.6 3.7e-66 223.3 23.6 1.0 1 0 0 1 1 1 1 Ceramidase DUF2583 PF10762.9 OWF56854.1 - 0.017 15.5 1.4 0.043 14.2 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) DUF5380 PF17351.2 OWF56857.1 - 0.089 12.7 0.4 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5380) Guanylate_cyc PF00211.20 OWF56858.1 - 1.9e-63 213.4 0.1 4.8e-63 212.1 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 OWF56858.1 - 2.2e-26 92.7 0.0 4.1e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OWF56858.1 - 1.2e-24 87.1 0.0 2.2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 OWF56858.1 - 2.8e-13 49.7 1.7 4.5e-13 49.0 1.7 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OWF56858.1 - 5e-06 26.4 0.0 8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein HNOBA PF07701.14 OWF56858.1 - 1.3e-05 24.7 0.3 2.3e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Heme NO binding associated Dynein_AAA_lid PF17852.1 OWF56858.1 - 0.05 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Secretin_N_2 PF07655.13 OWF56860.1 - 1.1e-09 38.7 2.2 1.2e+02 3.3 0.0 9.8 10 0 0 10 10 10 0 Secretin N-terminal domain EutK_C PF16365.5 OWF56860.1 - 2.3e-07 30.7 8.8 39 4.4 0.0 9.3 10 0 0 10 10 10 0 Ethanolamine utilization protein EutK C-terminus Herpes_gI PF01688.17 OWF56860.1 - 2.5e-06 27.5 12.6 8.8 6.2 0.0 7.7 1 1 8 9 9 9 5 Alphaherpesvirus glycoprotein I Ldr_toxin PF13940.6 OWF56860.1 - 0.00017 21.5 37.7 19 5.4 0.0 10.2 10 0 0 10 10 10 1 Toxin Ldr, type I toxin-antitoxin system CTD PF12815.7 OWF56860.1 - 0.00089 19.8 0.0 38 4.9 0.0 6.5 5 3 3 8 8 8 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4248 PF14053.6 OWF56860.1 - 3 7.9 5.1 33 4.6 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4248) DUF4208 PF13907.6 OWF56861.1 - 9.5e-07 29.2 0.0 2.9 8.4 0.0 4.8 1 1 4 5 5 5 1 Domain of unknown function (DUF4208) Spore_III_AB PF09548.10 OWF56861.1 - 0.0086 16.2 0.3 0.83 9.7 0.1 2.5 1 1 2 3 3 3 2 Stage III sporulation protein AB (spore_III_AB) DUF2267 PF10025.9 OWF56861.1 - 0.0099 16.1 12.1 0.33 11.2 3.8 3.3 1 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2267) Nsp1_C PF05064.13 OWF56861.1 - 0.011 15.6 6.6 22 4.9 0.1 4.6 2 2 3 5 5 5 0 Nsp1-like C-terminal region PRA-PH PF01503.17 OWF56861.1 - 0.014 15.8 1.6 16 6.0 0.1 3.3 1 1 2 3 3 3 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4375 PF14300.6 OWF56861.1 - 0.021 15.1 1.3 18 5.6 0.1 3.3 1 1 4 5 5 5 0 Domain of unknown function (DUF4375) DUF4400 PF14348.6 OWF56861.1 - 0.023 14.2 7.0 7.9 5.9 0.0 4.1 1 1 4 5 5 5 0 Domain of unknown function (DUF4400) DUF2357 PF09823.9 OWF56861.1 - 0.025 13.8 0.8 3.8 6.7 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF2357) SLED PF12140.8 OWF56861.1 - 0.029 14.9 0.5 2.1 8.9 0.1 2.6 1 1 1 2 2 2 0 SLED domain Bromo_TP PF07524.13 OWF56861.1 - 0.057 13.4 0.2 70 3.5 0.0 3.5 3 0 0 3 3 3 0 Bromodomain associated HTH_9 PF08221.11 OWF56861.1 - 0.059 13.5 0.0 51 4.1 0.0 3.3 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain CTD_bind PF04818.13 OWF56861.1 - 0.059 14.2 4.6 81 4.1 0.2 4.6 1 1 2 3 3 3 0 RNA polymerase II-binding domain. HAUS2 PF15003.6 OWF56861.1 - 0.081 12.6 1.9 0.23 11.2 0.2 2.4 1 1 1 3 3 3 0 HAUS augmin-like complex subunit 2 T4_Gp59_N PF08993.10 OWF56861.1 - 0.22 11.9 0.4 1.5e+02 2.9 0.0 3.8 2 2 2 4 4 4 0 T4 gene Gp59 loader of gp41 DNA helicase Prismane PF03063.20 OWF56861.1 - 0.27 9.9 4.1 2.8 6.5 0.5 2.1 1 1 1 2 2 2 0 Prismane/CO dehydrogenase family Gastrin PF00918.17 OWF56861.1 - 0.33 11.9 1.5 0.65 11.0 0.1 2.0 1 1 1 2 2 2 0 Gastrin/cholecystokinin family GAF PF01590.26 OWF56861.1 - 0.83 10.3 6.7 49 4.5 0.1 3.9 4 1 0 4 4 4 0 GAF domain DUF3040 PF11239.8 OWF56861.1 - 1 9.7 4.9 5.3 7.4 0.1 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3040) DASH_Hsk3 PF08227.11 OWF56861.1 - 7.8 7.0 37.5 13 6.3 3.0 5.1 5 0 0 5 5 5 0 DASH complex subunit Hsk3 like Apolipoprotein PF01442.18 OWF56862.1 - 0.0013 18.6 1.8 0.0042 17.0 1.8 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OWF56862.1 - 0.015 15.3 5.9 0.015 15.3 5.9 3.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2064 PF09837.9 OWF56862.1 - 0.035 13.9 0.4 9.2 6.1 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) TrwB_AAD_bind PF10412.9 OWF56862.1 - 0.036 13.0 1.9 0.62 8.9 0.1 2.3 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Alkyl_sulf_dimr PF14863.6 OWF56862.1 - 0.051 14.0 0.0 0.14 12.7 0.0 1.8 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation CheX PF13690.6 OWF56862.1 - 0.064 13.4 0.4 0.92 9.7 0.1 2.4 2 1 0 2 2 2 0 Chemotaxis phosphatase CheX DUF4777 PF16007.5 OWF56862.1 - 0.066 13.5 0.6 55 4.1 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4777) FANCI_S2 PF14676.6 OWF56862.1 - 0.73 10.1 8.1 1.7 9.0 2.6 2.7 1 1 1 2 2 2 0 FANCI solenoid 2 TrbL PF04610.14 OWF56862.1 - 1 9.0 4.6 0.63 9.8 0.4 2.4 2 1 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF3150 PF11348.8 OWF56863.1 - 0.002 17.4 0.1 0.0062 15.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3150) Baculo_PEP_C PF04513.12 OWF56863.1 - 0.037 14.1 0.5 0.037 14.1 0.5 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 OWF56863.1 - 0.053 11.5 0.3 0.065 11.2 0.3 1.3 1 0 0 1 1 1 0 Prominin Chlorosome_CsmC PF11098.8 OWF56863.1 - 0.14 12.1 3.0 1 9.3 0.8 2.4 1 1 1 2 2 2 0 Chlorosome envelope protein C HU-HIG PF18291.1 OWF56863.1 - 0.18 11.9 3.4 23 5.1 0.0 3.6 3 1 1 4 4 4 0 HU domain fused to wHTH, Ig, or Glycine-rich motif RhoGEF PF00621.20 OWF56864.1 - 3.6e-46 157.7 0.7 7.7e-46 156.6 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 OWF56864.1 - 3.1e-10 40.5 1.1 1.9e-09 38.0 1.1 2.4 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 OWF56864.1 - 2.4e-09 36.8 0.0 6.1e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OWF56864.1 - 4.5e-08 32.8 0.2 1.3e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OWF56864.1 - 1.3e-07 31.1 2.6 2.9e-07 30.0 2.6 1.6 1 0 0 1 1 1 1 SH3 domain Lamp PF01299.17 OWF56865.1 - 2e-21 76.4 2.5 1.4e-13 50.9 0.6 3.4 3 0 0 3 3 3 3 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 OWF56865.1 - 7.9e-11 42.0 0.9 0.00093 19.0 0.2 3.4 3 0 0 3 3 3 3 Vacuolar ATP synthase subunit S1 (ATP6S1) SKG6 PF08693.10 OWF56865.1 - 3.1 7.3 6.1 0.98 8.9 0.5 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain AMPKBI PF04739.15 OWF56866.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain zf-Di19 PF05605.12 OWF56867.1 - 0.0097 16.2 3.7 0.012 15.9 2.2 1.5 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 OWF56867.1 - 0.37 10.6 2.1 0.87 9.4 2.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-CCCH PF00642.24 OWF56868.1 - 4.1e-07 29.7 13.1 4.6e-06 26.4 3.0 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OWF56868.1 - 6.7e-06 25.8 0.1 2.5e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 OWF56868.1 - 0.0013 18.4 2.1 0.0013 18.4 2.1 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OWF56868.1 - 1.9 8.7 14.8 2.9 8.1 1.6 2.7 2 0 0 2 2 2 0 Zinc finger domain SNF PF00209.18 OWF56869.1 - 7.3e-144 480.3 34.9 1.9e-143 478.9 34.9 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Tugs PF17840.1 OWF56869.1 - 0.18 12.0 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Shisa PF13908.6 OWF56870.1 - 0.0055 17.0 0.8 0.0059 16.9 0.8 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Insulin_TMD PF17870.1 OWF56870.1 - 0.046 13.8 1.5 0.078 13.1 1.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PRIMA1 PF16101.5 OWF56870.1 - 0.074 13.1 0.6 0.082 12.9 0.6 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CYYR1 PF10873.8 OWF56870.1 - 0.092 13.2 2.6 0.11 13.0 2.6 1.1 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF4690 PF15756.5 OWF56870.1 - 0.1 13.2 0.2 0.12 13.0 0.2 1.2 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Syndecan PF01034.20 OWF56870.1 - 1.6 8.7 4.0 1.7 8.6 3.4 1.4 1 1 0 1 1 1 0 Syndecan domain BrkDBD PF09607.10 OWF56871.1 - 0.049 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain DUF2064 PF09837.9 OWF56872.1 - 2.1e-26 92.1 0.0 1e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2064) Glycos_transf_2 PF00535.26 OWF56872.1 - 2.5e-15 56.7 0.0 4.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OWF56872.1 - 9.2e-07 29.0 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CofC PF01983.16 OWF56872.1 - 0.0013 18.0 0.0 0.0065 15.7 0.0 2.1 2 0 0 2 2 2 1 Guanylyl transferase CofC like Glyco_tranf_2_2 PF10111.9 OWF56872.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 FGE-sulfatase PF03781.16 OWF56873.1 - 5.8e-82 275.2 8.8 7e-82 274.9 8.8 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 cNMP_binding PF00027.29 OWF56875.1 - 1.2e-39 134.2 0.0 6.4e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OWF56875.1 - 5.5e-14 51.5 0.1 1.2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit aGPT-Pplase1 PF18723.1 OWF56875.1 - 0.039 13.4 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Glyco_transf_92 PF01697.27 OWF56877.1 - 1.5e-48 165.7 6.9 2.7e-48 164.9 6.9 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Ldl_recept_a PF00057.18 OWF56878.1 - 5.9e-05 23.2 10.5 0.00017 21.7 10.5 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Shisa PF13908.6 OWF56878.1 - 0.00015 22.0 6.5 0.00015 22.0 6.5 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator CUB PF00431.20 OWF56878.1 - 0.0024 18.2 0.0 0.0058 17.0 0.0 1.7 1 0 0 1 1 1 1 CUB domain Orthoreo_P10 PF07204.11 OWF56878.1 - 0.019 14.9 0.9 0.26 11.3 0.3 2.5 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Glycophorin_A PF01102.18 OWF56878.1 - 0.094 13.0 0.0 0.094 13.0 0.0 1.7 2 0 0 2 2 2 0 Glycophorin A IlvN PF07991.12 OWF56879.1 - 0.00015 21.4 7.4 0.084 12.4 0.4 2.8 1 1 1 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain VirE1 PF12189.8 OWF56879.1 - 0.032 14.3 8.3 3.4 7.8 0.3 3.3 1 1 2 3 3 3 0 Single-strand DNA-binding protein Ribosomal_S3Ae PF01015.18 OWF56879.1 - 0.12 11.9 3.3 1.8 8.1 0.3 2.1 1 1 1 2 2 2 0 Ribosomal S3Ae family Sgf11_N PF18519.1 OWF56879.1 - 0.99 9.0 17.2 23 4.6 1.5 6.1 2 1 2 4 4 4 0 SAGA-associated factor 11 N-terminal domain IlvN PF07991.12 OWF56880.1 - 8.2e-05 22.2 8.6 0.043 13.4 0.8 3.1 1 1 2 3 3 3 3 Acetohydroxy acid isomeroreductase, NADPH-binding domain MRP-L27 PF09809.9 OWF56880.1 - 0.009 15.8 1.0 2.7 7.9 0.3 2.5 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L27 UMP1 PF05348.11 OWF56880.1 - 0.026 14.7 4.3 7.9 6.7 0.1 3.6 1 1 1 2 2 2 0 Proteasome maturation factor UMP1 VirE1 PF12189.8 OWF56880.1 - 0.19 11.9 9.0 5.6 7.1 0.5 4.0 1 1 4 5 5 5 0 Single-strand DNA-binding protein COMPASS-Shg1 PF05205.12 OWF56880.1 - 0.53 11.0 9.9 5.4 7.8 3.2 2.4 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 L_protein_N PF15518.6 OWF56880.1 - 3.9 7.4 14.6 41 4.1 6.0 4.1 1 1 2 3 3 3 0 L protein N-terminus # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Mizuhopecten_yessoensis-ASM211388v2/GCA_002113885.2_ASM211388v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Mizuhopecten_yessoensis-ASM211388v2/GCA_002113885.2_ASM211388v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Mizuhopecten_yessoensis-ASM211388v2/GCA_002113885.2_ASM211388v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Mizuhopecten_yessoensis-ASM211388v2/GCA_002113885.2_ASM211388v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 19:03:58 2019 # [ok]